Query header	GN	Description Estimated PPV, description	Biological process Estimated PPV, GO-id, description	Molecular function Estimated PPV, GO-id, description	Cellular component Estimated PPV, GO-id, description	Inverse ec2go, kegg2go
tr|F7GNE4|F7GNE4_MACMU Catenin beta-1 Search	CTNNB1	0.88 Catenin (Cadherin-associated protein) beta 1	0.84 GO:1904499 regulation of chromatin-mediated maintenance of transcription 0.84 GO:1904793 regulation of euchromatin binding 0.84 GO:1904501 positive regulation of chromatin-mediated maintenance of transcription 0.84 GO:0061324 canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation 0.84 GO:0072054 renal outer medulla development 0.83 GO:0072053 renal inner medulla development 0.83 GO:0061198 fungiform papilla formation 0.83 GO:0044334 canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition 0.83 GO:0003340 negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis 0.83 GO:0045976 negative regulation of mitotic cell cycle, embryonic	0.78 GO:0070411 I-SMAD binding 0.76 GO:0045294 alpha-catenin binding 0.75 GO:0030331 estrogen receptor binding 0.73 GO:0097718 disordered domain specific binding 0.72 GO:0001102 RNA polymerase II activating transcription factor binding 0.72 GO:0035258 steroid hormone receptor binding 0.72 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 0.72 GO:0070491 repressing transcription factor binding 0.71 GO:0033613 activating transcription factor binding 0.71 GO:0044325 ion channel binding	0.83 GO:0070369 beta-catenin-TCF7L2 complex 0.82 GO:0034750 Scrib-APC-beta-catenin complex 0.82 GO:0071664 catenin-TCF7L2 complex 0.81 GO:1990907 beta-catenin-TCF complex 0.80 GO:1990909 Wnt signalosome 0.78 GO:0005916 fascia adherens 0.78 GO:0016600 flotillin complex 0.77 GO:0031528 microvillus membrane 0.76 GO:0016342 catenin complex 0.76 GO:0030877 beta-catenin destruction complex
tr|F7HCV5|F7HCV5_MACMU Uncharacterized protein Search	TGFB1	0.93 Transforming growth factor beta	0.87 GO:1901664 regulation of NAD+ ADP-ribosyltransferase activity 0.87 GO:1901666 positive regulation of NAD+ ADP-ribosyltransferase activity 0.87 GO:1900126 negative regulation of hyaluronan biosynthetic process 0.86 GO:0043932 ossification involved in bone remodeling 0.85 GO:0048298 positive regulation of isotype switching to IgA isotypes 0.85 GO:1900125 regulation of hyaluronan biosynthetic process 0.85 GO:0007182 common-partner SMAD protein phosphorylation 0.85 GO:0048296 regulation of isotype switching to IgA isotypes 0.84 GO:0007183 SMAD protein complex assembly 0.84 GO:0010936 negative regulation of macrophage cytokine production	0.85 GO:0034714 type III transforming growth factor beta receptor binding 0.84 GO:0005114 type II transforming growth factor beta receptor binding 0.83 GO:0034713 type I transforming growth factor beta receptor binding 0.81 GO:0005160 transforming growth factor beta receptor binding 0.78 GO:0003823 antigen binding 0.74 GO:0001948 glycoprotein binding 0.72 GO:0005126 cytokine receptor binding 0.71 GO:0043539 protein serine/threonine kinase activator activity 0.71 GO:0008083 growth factor activity 0.68 GO:0030295 protein kinase activator activity	0.75 GO:0072562 blood microparticle 0.74 GO:0005902 microvillus 0.70 GO:0098858 actin-based cell projection 0.69 GO:0031093 platelet alpha granule lumen 0.66 GO:0009986 cell surface 0.65 GO:0005796 Golgi lumen 0.64 GO:0034774 secretory granule lumen 0.64 GO:0005615 extracellular space 0.63 GO:0060205 cytoplasmic vesicle lumen 0.63 GO:0031983 vesicle lumen
sp|P56424|P53_MACMU Cellular tumor antigen p53 Search	TP53	0.82 Cellular tumor antigen p53	0.86 GO:0097252 oligodendrocyte apoptotic process 0.84 GO:0034349 glial cell apoptotic process 0.83 GO:0072717 cellular response to actinomycin D 0.82 GO:0072716 response to actinomycin D 0.82 GO:0090403 oxidative stress-induced premature senescence 0.81 GO:0090400 stress-induced premature senescence 0.80 GO:0006983 ER overload response 0.80 GO:0090200 positive regulation of release of cytochrome c from mitochondria 0.80 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 0.80 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	0.77 GO:0035035 histone acetyltransferase binding 0.76 GO:0051721 protein phosphatase 2A binding 0.75 GO:0097718 disordered domain specific binding 0.74 GO:0002039 p53 binding 0.74 GO:0043621 protein self-association 0.73 GO:0047485 protein N-terminus binding 0.73 GO:0030971 receptor tyrosine kinase binding 0.73 GO:1990782 protein tyrosine kinase binding 0.73 GO:0042826 histone deacetylase binding 0.73 GO:0001046 core promoter sequence-specific DNA binding	0.73 GO:0016605 PML body 0.73 GO:0016363 nuclear matrix 0.69 GO:0034399 nuclear periphery 0.69 GO:0005669 transcription factor TFIID complex 0.65 GO:0016604 nuclear body 0.65 GO:0090575 RNA polymerase II transcription factor complex 0.64 GO:0000790 nuclear chromatin 0.64 GO:0044798 nuclear transcription factor complex 0.63 GO:0016591 DNA-directed RNA polymerase II, holoenzyme 0.63 GO:0055029 nuclear DNA-directed RNA polymerase complex
sp|F7EQ49|GPER1_MACMU G-protein coupled estrogen receptor 1 Search	GPER1	0.97 G protein-coupled estrogen receptor 0.49 G protein-coupled receptor 30	0.82 GO:2000724 positive regulation of cardiac vascular smooth muscle cell differentiation 0.82 GO:2000722 regulation of cardiac vascular smooth muscle cell differentiation 0.81 GO:0070474 positive regulation of uterine smooth muscle contraction 0.80 GO:0031959 mineralocorticoid receptor signaling pathway 0.80 GO:0032962 positive regulation of inositol trisphosphate biosynthetic process 0.79 GO:0070472 regulation of uterine smooth muscle contraction 0.79 GO:1905065 positive regulation of vascular smooth muscle cell differentiation 0.78 GO:0032960 regulation of inositol trisphosphate biosynthetic process 0.78 GO:0030264 nuclear fragmentation involved in apoptotic nuclear change 0.78 GO:0060732 positive regulation of inositol phosphate biosynthetic process	0.80 GO:0017082 mineralocorticoid receptor activity 0.78 GO:1990239 steroid hormone binding 0.74 GO:0030284 estrogen receptor activity 0.71 GO:0042562 hormone binding 0.67 GO:0004945 angiotensin type II receptor activity 0.67 GO:0005496 steroid binding 0.67 GO:0001595 angiotensin receptor activity 0.64 GO:0003707 steroid hormone receptor activity 0.63 GO:0004930 G-protein coupled receptor activity 0.62 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding	0.77 GO:0044327 dendritic spine head 0.76 GO:0032591 dendritic spine membrane 0.72 GO:0032590 dendrite membrane 0.68 GO:0043198 dendritic shaft 0.68 GO:0032589 neuron projection membrane 0.68 GO:0055037 recycling endosome 0.68 GO:0045095 keratin filament 0.67 GO:0043197 dendritic spine 0.67 GO:0044309 neuron spine 0.66 GO:0042734 presynaptic membrane
tr|F7ACJ7|F7ACJ7_MACMU Putative uncharacterized protein Search	BMP4	0.75 Bone morphogenetic protein 4	0.85 GO:0061149 BMP signaling pathway involved in ureter morphogenesis 0.85 GO:0061150 renal system segmentation 0.85 GO:0061151 BMP signaling pathway involved in renal system segmentation 0.85 GO:0072192 ureter epithelial cell differentiation 0.85 GO:0071893 BMP signaling pathway involved in nephric duct formation 0.85 GO:0061155 pulmonary artery endothelial tube morphogenesis 0.85 GO:2000005 negative regulation of metanephric S-shaped body morphogenesis 0.85 GO:2000007 negative regulation of metanephric comma-shaped body morphogenesis 0.85 GO:0055018 regulation of cardiac muscle fiber development 0.85 GO:2000004 regulation of metanephric S-shaped body morphogenesis	0.80 GO:0070700 BMP receptor binding 0.79 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 0.78 GO:0039706 co-receptor binding 0.77 GO:0033612 receptor serine/threonine kinase binding 0.76 GO:0042056 chemoattractant activity 0.71 GO:0008083 growth factor activity 0.70 GO:0005160 transforming growth factor beta receptor binding 0.68 GO:0008201 heparin binding 0.67 GO:0005125 cytokine activity 0.62 GO:0005126 cytokine receptor binding	0.58 GO:0005576 extracellular region 0.58 GO:0005615 extracellular space 0.58 GO:0005578 proteinaceous extracellular matrix 0.57 GO:0005788 endoplasmic reticulum lumen 0.56 GO:0031012 extracellular matrix 0.56 GO:0044421 extracellular region part 0.43 GO:0044432 endoplasmic reticulum part 0.40 GO:0031982 vesicle 0.40 GO:0005783 endoplasmic reticulum 0.35 GO:0070013 intracellular organelle lumen
sp|Q0PF16|TRIM5_MACMU Tripartite motif-containing protein 5 Search	TRIM5	0.97 Tripartite motif-containing 5 transcript variant alpha	0.80 GO:0031664 regulation of lipopolysaccharide-mediated signaling pathway 0.78 GO:0070534 protein K63-linked ubiquitination 0.74 GO:0046597 negative regulation of viral entry into host cell 0.74 GO:0051092 positive regulation of NF-kappaB transcription factor activity 0.73 GO:1902187 negative regulation of viral release from host cell 0.73 GO:0002831 regulation of response to biotic stimulus 0.73 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling 0.72 GO:0045087 innate immune response 0.72 GO:0002221 pattern recognition receptor signaling pathway 0.72 GO:0002758 innate immune response-activating signal transduction	0.78 GO:0008329 signaling pattern recognition receptor activity 0.78 GO:0038187 pattern recognition receptor activity 0.66 GO:0004842 ubiquitin-protein transferase activity 0.66 GO:0019787 ubiquitin-like protein transferase activity 0.63 GO:0030674 protein binding, bridging 0.62 GO:0060090 binding, bridging 0.59 GO:0019901 protein kinase binding 0.59 GO:0019900 kinase binding 0.56 GO:0042803 protein homodimerization activity 0.54 GO:0042802 identical protein binding	0.76 GO:1990462 omegasome 0.71 GO:0000932 P-body 0.69 GO:0036464 cytoplasmic ribonucleoprotein granule 0.68 GO:0035770 ribonucleoprotein granule 0.47 GO:0030529 intracellular ribonucleoprotein complex 0.47 GO:1990904 ribonucleoprotein complex 0.47 GO:0012505 endomembrane system 0.46 GO:0005634 nucleus 0.45 GO:0043232 intracellular non-membrane-bounded organelle 0.44 GO:0043228 non-membrane-bounded organelle	0.34 EC:2 GO:0016740 0.66 KEGG:R03876 GO:0004842
tr|F7H8I5|F7H8I5_MACMU Uncharacterized protein Search	NOTCH1B	0.96 Receptor protein Notch1	0.71 GO:0007219 Notch signaling pathway 0.59 GO:0030154 cell differentiation 0.59 GO:0007166 cell surface receptor signaling pathway 0.58 GO:0048869 cellular developmental process 0.57 GO:0003270 Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation 0.57 GO:0003169 coronary vein morphogenesis 0.57 GO:0007275 multicellular organism development 0.56 GO:0060843 venous endothelial cell differentiation 0.56 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis 0.56 GO:0003213 cardiac right atrium morphogenesis	0.57 GO:0005509 calcium ion binding 0.52 GO:0005112 Notch binding 0.51 GO:0001190 transcriptional activator activity, RNA polymerase II transcription factor binding 0.51 GO:0098811 transcriptional repressor activity, RNA polymerase II activating transcription factor binding 0.50 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding 0.50 GO:0031490 chromatin DNA binding 0.49 GO:0004872 receptor activity 0.49 GO:0060089 molecular transducer activity 0.49 GO:0001047 core promoter binding 0.46 GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding	0.56 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex 0.49 GO:0016324 apical plasma membrane 0.49 GO:0005796 Golgi lumen 0.49 GO:0045177 apical part of cell 0.48 GO:0001669 acrosomal vesicle 0.47 GO:0043235 receptor complex 0.47 GO:0005912 adherens junction 0.47 GO:0070161 anchoring junction 0.47 GO:0097223 sperm part 0.46 GO:0001726 ruffle
tr|F6ZJX4|F6ZJX4_MACMU Uncharacterized protein Search	TGFB2	0.81 Transforming growth factor beta-2	0.85 GO:0045726 positive regulation of integrin biosynthetic process 0.85 GO:0051795 positive regulation of timing of catagen 0.85 GO:0010693 negative regulation of alkaline phosphatase activity 0.84 GO:0051794 regulation of timing of catagen 0.84 GO:0045113 regulation of integrin biosynthetic process 0.84 GO:0051891 positive regulation of cardioblast differentiation 0.84 GO:0048818 positive regulation of hair follicle maturation 0.83 GO:0010936 negative regulation of macrophage cytokine production 0.83 GO:0010692 regulation of alkaline phosphatase activity 0.83 GO:0048819 regulation of hair follicle maturation	0.84 GO:0034714 type III transforming growth factor beta receptor binding 0.83 GO:0005114 type II transforming growth factor beta receptor binding 0.81 GO:0005160 transforming growth factor beta receptor binding 0.77 GO:0001540 amyloid-beta binding 0.72 GO:0005126 cytokine receptor binding 0.71 GO:0008083 growth factor activity 0.69 GO:0004702 signal transducer, downstream of receptor, with serine/threonine kinase activity 0.68 GO:0042277 peptide binding 0.68 GO:0005057 signal transducer activity, downstream of receptor 0.64 GO:0042803 protein homodimerization activity	0.68 GO:0031093 platelet alpha granule lumen 0.64 GO:0005615 extracellular space 0.63 GO:0031012 extracellular matrix 0.63 GO:0034774 secretory granule lumen 0.63 GO:0060205 cytoplasmic vesicle lumen 0.63 GO:0031983 vesicle lumen 0.62 GO:0031091 platelet alpha granule 0.62 GO:0043025 neuronal cell body 0.62 GO:0044421 extracellular region part 0.62 GO:0044297 cell body	0.69 EC:2.7.11 GO:0004702

Query header	GN	Description Estimated PPV, description	Biological process Estimated PPV, GO-id, description	Molecular function Estimated PPV, GO-id, description	Cellular component Estimated PPV, GO-id, description	Inverse ec2go, kegg2go
sp|P61143|SYUA_MACMU Alpha-synuclein Search	SNCA	0.97 Alpha-synuclein	0.86 GO:0051945 negative regulation of catecholamine uptake involved in synaptic transmission 0.86 GO:0051621 regulation of norepinephrine uptake 0.86 GO:0051622 negative regulation of norepinephrine uptake 0.86 GO:1903284 positive regulation of glutathione peroxidase activity 0.86 GO:1903285 positive regulation of hydrogen peroxide catabolic process 0.86 GO:1903282 regulation of glutathione peroxidase activity 0.86 GO:0051585 negative regulation of dopamine uptake involved in synaptic transmission 0.86 GO:1904715 negative regulation of chaperone-mediated autophagy 0.86 GO:2000295 regulation of hydrogen peroxide catabolic process 0.86 GO:0032227 negative regulation of synaptic transmission, dopaminergic	0.82 GO:0048156 tau protein binding 0.81 GO:0050544 arachidonic acid binding 0.81 GO:0050542 icosanoid binding 0.81 GO:0050543 icosatetraenoic acid binding 0.80 GO:1903136 cuprous ion binding 0.79 GO:0036041 long-chain fatty acid binding 0.78 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 0.77 GO:0030544 Hsp70 protein binding 0.77 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 0.77 GO:0043014 alpha-tubulin binding	0.83 GO:0031092 platelet alpha granule membrane 0.78 GO:0031091 platelet alpha granule 0.74 GO:0016234 inclusion body 0.74 GO:0030667 secretory granule membrane 0.74 GO:0030426 growth cone 0.69 GO:0030141 secretory granule 0.69 GO:0043025 neuronal cell body 0.68 GO:0044297 cell body 0.68 GO:0030427 site of polarized growth 0.68 GO:0030424 axon	0.30 EC:1 GO:0016491
tr|F7AGU8|F7AGU8_MACMU Presenilin Search	PSEN1	0.77 Presenilin	0.86 GO:1904797 negative regulation of core promoter binding 0.86 GO:0021870 Cajal-Retzius cell differentiation 0.85 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis 0.84 GO:0034205 amyloid-beta formation 0.84 GO:0042987 amyloid precursor protein catabolic process 0.84 GO:0002265 astrocyte activation involved in immune response 0.83 GO:0042982 amyloid precursor protein metabolic process 0.83 GO:0016080 synaptic vesicle targeting 0.83 GO:0060075 regulation of resting membrane potential 0.83 GO:0048143 astrocyte activation	0.83 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving 0.75 GO:0030165 PDZ domain binding 0.72 GO:0008013 beta-catenin binding 0.70 GO:0045296 cadherin binding 0.68 GO:0050839 cell adhesion molecule binding 0.67 GO:0005262 calcium channel activity 0.65 GO:0019904 protein domain specific binding 0.64 GO:0015085 calcium ion transmembrane transporter activity 0.61 GO:0004190 aspartic-type endopeptidase activity 0.61 GO:0070001 aspartic-type peptidase activity	0.81 GO:0070765 gamma-secretase complex 0.79 GO:0005790 smooth endoplasmic reticulum 0.79 GO:0005640 nuclear outer membrane 0.79 GO:0035253 ciliary rootlet 0.77 GO:0043198 dendritic shaft 0.77 GO:0016235 aggresome 0.75 GO:0016234 inclusion body 0.74 GO:0030426 growth cone 0.71 GO:0005791 rough endoplasmic reticulum 0.71 GO:0031594 neuromuscular junction	0.83 EC:3.4.23 GO:0042500