Query header	GN	Description Estimated PPV, description	Biological process Estimated PPV, GO-id, description	Molecular function Estimated PPV, GO-id, description	Cellular component Estimated PPV, GO-id, description	Inverse ec2go, kegg2go
tr|F7GNE4|F7GNE4_MACMU Catenin beta-1 Search	CTNNB1	0.90 Catenin beta 1 0.36 Beta-catenin	0.71 GO:0007155 cell adhesion 0.70 GO:0044334 canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition 0.70 GO:0070602 regulation of centromeric sister chromatid cohesion 0.69 GO:0072497 mesenchymal stem cell differentiation 0.69 GO:0010909 positive regulation of heparan sulfate proteoglycan biosynthetic process 0.69 GO:0030997 regulation of centriole-centriole cohesion 0.69 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation 0.69 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process 0.69 GO:0061324 canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation 0.69 GO:0071681 cellular response to indole-3-methanol	0.84 GO:0045296 cadherin binding 0.81 GO:0050839 cell adhesion molecule binding 0.68 GO:0045294 alpha-catenin binding 0.67 GO:0070411 I-SMAD binding 0.66 GO:0030331 nuclear estrogen receptor binding 0.65 GO:0001222 transcription corepressor binding 0.65 GO:1990226 histone methyltransferase binding 0.64 GO:0001221 transcription coregulator binding 0.64 GO:0097718 disordered domain specific binding 0.64 GO:0044325 transmembrane transporter binding	0.80 GO:0005912 adherens junction 0.75 GO:0005911 cell-cell junction 0.74 GO:0070161 anchoring junction 0.70 GO:0030054 cell junction 0.69 GO:0070369 beta-catenin-TCF7L2 complex 0.69 GO:0071664 catenin-TCF7L2 complex 0.68 GO:0030877 beta-catenin destruction complex 0.68 GO:0034750 Scrib-APC-beta-catenin complex 0.68 GO:1990711 beta-catenin-ICAT complex 0.67 GO:1990907 beta-catenin-TCF complex
tr|F7HCV5|F7HCV5_MACMU Uncharacterized protein Search	TGFB1	0.87 Transforming growth factor beta	0.82 GO:0051781 positive regulation of cell division 0.79 GO:0051302 regulation of cell division 0.69 GO:0014008 positive regulation of microglia differentiation 0.69 GO:0014006 regulation of microglia differentiation 0.69 GO:0010763 positive regulation of fibroblast migration 0.69 GO:0032967 positive regulation of collagen biosynthetic process 0.68 GO:0010714 positive regulation of collagen metabolic process 0.68 GO:0060389 pathway-restricted SMAD protein phosphorylation 0.68 GO:0032740 positive regulation of interleukin-17 production 0.68 GO:0048522 positive regulation of cellular process	0.85 GO:0005160 transforming growth factor beta receptor binding 0.78 GO:0005126 cytokine receptor binding 0.77 GO:0008083 growth factor activity 0.75 GO:0048018 receptor ligand activity 0.75 GO:0030546 signaling receptor activator activity 0.75 GO:0030545 signaling receptor regulator activity 0.72 GO:0005102 signaling receptor binding 0.67 GO:0098772 molecular function regulator activity 0.63 GO:0005515 protein binding 0.61 GO:0034714 type III transforming growth factor beta receptor binding	0.72 GO:0005615 extracellular space 0.65 GO:0005576 extracellular region 0.61 GO:0072562 blood microparticle 0.56 GO:0031012 extracellular matrix 0.52 GO:0009986 cell surface 0.51 GO:0030312 external encapsulating structure 0.45 GO:0005634 nucleus 0.44 GO:0005737 cytoplasm 0.43 GO:0005902 microvillus 0.43 GO:0071944 cell periphery
sp|P56424|P53_MACMU Cellular tumor antigen p53 Search	TP53	0.79 Cellular tumor antigen p53	0.76 GO:0048511 rhythmic process 0.76 GO:0006915 apoptotic process 0.75 GO:0012501 programmed cell death 0.75 GO:0008219 cell death 0.74 GO:0051262 protein tetramerization 0.70 GO:0045893 positive regulation of DNA-templated transcription 0.70 GO:1903508 positive regulation of nucleic acid-templated transcription 0.70 GO:1902680 positive regulation of RNA biosynthetic process 0.70 GO:0051254 positive regulation of RNA metabolic process 0.70 GO:0045935 positive regulation of nucleobase-containing compound metabolic process	0.75 GO:0000976 transcription cis-regulatory region binding 0.75 GO:0001067 transcription regulatory region nucleic acid binding 0.74 GO:1990837 sequence-specific double-stranded DNA binding 0.72 GO:0003690 double-stranded DNA binding 0.67 GO:0043565 sequence-specific DNA binding 0.62 GO:0003700 DNA-binding transcription factor activity 0.62 GO:0140110 transcription regulator activity 0.59 GO:0036310 ATP-dependent DNA/DNA annealing activity 0.58 GO:1990814 DNA/DNA annealing activity 0.56 GO:0035033 histone deacetylase regulator activity	0.80 GO:0016605 PML body 0.74 GO:0016604 nuclear body 0.73 GO:0005759 mitochondrial matrix 0.71 GO:0005815 microtubule organizing center 0.69 GO:0005654 nucleoplasm 0.67 GO:0015630 microtubule cytoskeleton 0.66 GO:0031981 nuclear lumen 0.66 GO:0005783 endoplasmic reticulum 0.65 GO:0070013 intracellular organelle lumen 0.65 GO:0043233 organelle lumen
sp|F7EQ49|GPER1_MACMU G-protein coupled estrogen receptor 1 Search	GPER1	0.97 G protein-coupled estrogen receptor 1 0.15 G-protein coupled receptors family 1 profile domain-containing protein	0.72 GO:2000724 positive regulation of cardiac vascular smooth muscle cell differentiation 0.72 GO:2000722 regulation of cardiac vascular smooth muscle cell differentiation 0.71 GO:0070474 positive regulation of uterine smooth muscle contraction 0.70 GO:0032962 positive regulation of inositol trisphosphate biosynthetic process 0.69 GO:0070472 regulation of uterine smooth muscle contraction 0.69 GO:1905065 positive regulation of vascular associated smooth muscle cell differentiation 0.69 GO:0032960 regulation of inositol trisphosphate biosynthetic process 0.69 GO:0007186 G protein-coupled receptor signaling pathway 0.69 GO:0060732 positive regulation of inositol phosphate biosynthetic process 0.69 GO:0051152 positive regulation of smooth muscle cell differentiation	0.71 GO:0004930 G protein-coupled receptor activity 0.69 GO:1990239 steroid hormone binding 0.69 GO:0004888 transmembrane signaling receptor activity 0.68 GO:0038023 signaling receptor activity 0.68 GO:0060089 molecular transducer activity 0.67 GO:0030284 nuclear estrogen receptor activity 0.64 GO:0003707 nuclear steroid receptor activity 0.63 GO:0042562 hormone binding 0.62 GO:0005496 steroid binding 0.60 GO:0003682 chromatin binding	0.67 GO:0098686 hippocampal mossy fiber to CA3 synapse 0.62 GO:0045095 keratin filament 0.62 GO:0098984 neuron to neuron synapse 0.61 GO:0005802 trans-Golgi network 0.60 GO:0055037 recycling endosome 0.60 GO:0048471 perinuclear region of cytoplasm 0.59 GO:0005882 intermediate filament 0.59 GO:0045111 intermediate filament cytoskeleton 0.59 GO:0098791 Golgi apparatus subcompartment 0.59 GO:0005769 early endosome
tr|F7ACJ7|F7ACJ7_MACMU Putative uncharacterized protein Search	BMP4	0.89 Bone morphogenetic protein 4 0.28 TGF-beta family profile domain-containing protein	0.71 GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis 0.71 GO:0060503 bud dilation involved in lung branching 0.71 GO:0072100 specification of ureteric bud anterior/posterior symmetry 0.71 GO:0072096 negative regulation of branch elongation involved in ureteric bud branching 0.71 GO:0072101 specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway 0.71 GO:0090194 negative regulation of glomerulus development 0.71 GO:0072097 negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway 0.71 GO:0072099 anterior/posterior pattern specification involved in ureteric bud development 0.71 GO:0071893 BMP signaling pathway involved in nephric duct formation 0.71 GO:0061155 pulmonary artery endothelial tube morphogenesis	0.77 GO:0008083 growth factor activity 0.75 GO:0048018 receptor ligand activity 0.75 GO:0030546 signaling receptor activator activity 0.75 GO:0030545 signaling receptor regulator activity 0.72 GO:0005102 signaling receptor binding 0.69 GO:0070700 BMP receptor binding 0.68 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 0.68 GO:0039706 co-receptor binding 0.67 GO:0098772 molecular function regulator activity 0.67 GO:0033612 receptor serine/threonine kinase binding	0.65 GO:0005576 extracellular region 0.57 GO:0005615 extracellular space 0.35 GO:0005788 endoplasmic reticulum lumen 0.34 GO:0005783 endoplasmic reticulum 0.34 GO:0070013 intracellular organelle lumen 0.34 GO:0043233 organelle lumen 0.34 GO:0031974 membrane-enclosed lumen 0.34 GO:0012505 endomembrane system 0.33 GO:0043231 intracellular membrane-bounded organelle 0.33 GO:0043227 membrane-bounded organelle
sp|Q0PF16|TRIM5_MACMU Tripartite motif-containing protein 5 Search	TRIM5	0.91 Tripartite motif-containing protein 5	0.76 GO:0045087 innate immune response 0.74 GO:0006914 autophagy 0.74 GO:0061919 process utilizing autophagic mechanism 0.74 GO:0051607 defense response to virus 0.74 GO:0140546 defense response to symbiont 0.73 GO:0009615 response to virus 0.72 GO:0006955 immune response 0.71 GO:0002376 immune system process 0.70 GO:0016567 protein ubiquitination 0.70 GO:0032446 protein modification by small protein conjugation	0.68 GO:0038187 pattern recognition receptor activity 0.63 GO:0008270 zinc ion binding 0.61 GO:0046914 transition metal ion binding 0.57 GO:0004842 ubiquitin-protein transferase activity 0.57 GO:0019787 ubiquitin-like protein transferase activity 0.56 GO:0016755 aminoacyltransferase activity 0.54 GO:0038023 signaling receptor activity 0.54 GO:0060089 molecular transducer activity 0.53 GO:0046872 metal ion binding 0.53 GO:0043169 cation binding	0.61 GO:0000932 P-body 0.60 GO:0036464 cytoplasmic ribonucleoprotein granule 0.60 GO:0035770 ribonucleoprotein granule 0.58 GO:0005634 nucleus 0.56 GO:1990462 omegasome 0.55 GO:0099080 supramolecular complex 0.54 GO:0043231 intracellular membrane-bounded organelle 0.54 GO:0043227 membrane-bounded organelle 0.50 GO:0043229 intracellular organelle 0.50 GO:0043226 organelle	0.56 EC:2.3.2.- GO:0016755 0.57 KEGG:R03876 GO:0004842
tr|F7H8I5|F7H8I5_MACMU Uncharacterized protein Search			0.81 GO:0001525 angiogenesis 0.80 GO:0048514 blood vessel morphogenesis 0.80 GO:0001568 blood vessel development 0.80 GO:0007219 Notch signaling pathway 0.80 GO:0001944 vasculature development 0.79 GO:0035239 tube morphogenesis 0.78 GO:0035295 tube development 0.78 GO:0072359 circulatory system development 0.75 GO:0048646 anatomical structure formation involved in morphogenesis 0.71 GO:0009653 anatomical structure morphogenesis	0.69 GO:0005509 calcium ion binding 0.68 GO:0038023 signaling receptor activity 0.68 GO:0060089 molecular transducer activity 0.63 GO:0140537 transcription regulator activator activity 0.61 GO:0005112 Notch binding 0.59 GO:0031490 chromatin DNA binding 0.57 GO:0003713 transcription coactivator activity 0.56 GO:0003682 chromatin binding 0.55 GO:0003712 transcription coregulator activity 0.55 GO:0042802 identical protein binding	0.66 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex 0.60 GO:0005634 nucleus 0.58 GO:0005912 adherens junction 0.57 GO:0043235 receptor complex 0.55 GO:0005911 cell-cell junction 0.55 GO:0043231 intracellular membrane-bounded organelle 0.55 GO:0009986 cell surface 0.55 GO:0043227 membrane-bounded organelle 0.54 GO:0070161 anchoring junction 0.54 GO:0016324 apical plasma membrane
tr|F6ZJX4|F6ZJX4_MACMU Uncharacterized protein Search	TGFB2	0.84 Transforming growth factor beta	0.82 GO:0051781 positive regulation of cell division 0.79 GO:0051302 regulation of cell division 0.77 GO:0009790 embryo development 0.75 GO:0009888 tissue development 0.73 GO:0051795 positive regulation of timing of catagen 0.73 GO:0051794 regulation of timing of catagen 0.73 GO:0045726 positive regulation of integrin biosynthetic process 0.73 GO:0010693 negative regulation of alkaline phosphatase activity 0.72 GO:0051891 positive regulation of cardioblast differentiation 0.72 GO:0048818 positive regulation of hair follicle maturation	0.85 GO:0005160 transforming growth factor beta receptor binding 0.78 GO:0005126 cytokine receptor binding 0.77 GO:0008083 growth factor activity 0.75 GO:0048018 receptor ligand activity 0.75 GO:0030546 signaling receptor activator activity 0.75 GO:0030545 signaling receptor regulator activity 0.73 GO:0034714 type III transforming growth factor beta receptor binding 0.72 GO:0005102 signaling receptor binding 0.72 GO:0005114 type II transforming growth factor beta receptor binding 0.67 GO:0098772 molecular function regulator activity	0.72 GO:0005615 extracellular space 0.65 GO:0005576 extracellular region 0.62 GO:0062023 collagen-containing extracellular matrix 0.61 GO:0031012 extracellular matrix 0.55 GO:0030312 external encapsulating structure 0.46 GO:0071944 cell periphery 0.35 GO:0043025 neuronal cell body 0.35 GO:0044297 cell body 0.35 GO:0030424 axon 0.35 GO:0036477 somatodendritic compartment

Query header	GN	Description Estimated PPV, description	Biological process Estimated PPV, GO-id, description	Molecular function Estimated PPV, GO-id, description	Cellular component Estimated PPV, GO-id, description	Inverse ec2go, kegg2go
sp|P61143|SYUA_MACMU Alpha-synuclein Search	SNCA	0.97 Alpha-synuclein	0.86 GO:0014059 regulation of dopamine secretion 0.85 GO:0050433 regulation of catecholamine secretion 0.85 GO:0051952 regulation of amine transport 0.80 GO:1903530 regulation of secretion by cell 0.80 GO:0051046 regulation of secretion 0.73 GO:0051049 regulation of transport 0.72 GO:0032879 regulation of localization 0.64 GO:0051945 negative regulation of catecholamine uptake involved in synaptic transmission 0.64 GO:0051622 negative regulation of norepinephrine uptake 0.64 GO:1903284 positive regulation of glutathione peroxidase activity	0.63 GO:1903136 cuprous ion binding 0.61 GO:0050544 arachidonic acid binding 0.61 GO:0050543 icosatetraenoic acid binding 0.61 GO:0050542 icosanoid binding 0.61 GO:0048156 tau protein binding 0.60 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 0.60 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 0.60 GO:0036041 long-chain fatty acid binding 0.58 GO:0070840 dynein complex binding 0.58 GO:0043014 alpha-tubulin binding	0.78 GO:0030424 axon 0.75 GO:0043005 neuron projection 0.72 GO:0045202 synapse 0.71 GO:0120025 plasma membrane bounded cell projection 0.71 GO:0030054 cell junction 0.68 GO:0042995 cell projection 0.65 GO:0005576 extracellular region 0.62 GO:0031092 platelet alpha granule membrane 0.60 GO:0031091 platelet alpha granule 0.59 GO:0005634 nucleus	0.43 EC:1.-.-.- GO:0016491
tr|F7AGU8|F7AGU8_MACMU Presenilin Search	PSEN1	0.74 Presenilin 0.49 Presenilin-1 isoform X1	0.85 GO:0042987 amyloid precursor protein catabolic process 0.85 GO:0042982 amyloid precursor protein metabolic process 0.79 GO:0007219 Notch signaling pathway 0.76 GO:0006915 apoptotic process 0.75 GO:0012501 programmed cell death 0.75 GO:0008219 cell death 0.72 GO:0016485 protein processing 0.71 GO:1904797 negative regulation of core promoter binding 0.70 GO:0051604 protein maturation 0.70 GO:0007155 cell adhesion	0.86 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving 0.71 GO:0004190 aspartic-type endopeptidase activity 0.71 GO:0070001 aspartic-type peptidase activity 0.65 GO:0004175 endopeptidase activity 0.65 GO:0030165 PDZ domain binding 0.64 GO:0051117 ATPase binding 0.63 GO:0008013 beta-catenin binding 0.62 GO:0070851 growth factor receptor binding 0.62 GO:0045296 cadherin binding 0.61 GO:0008233 peptidase activity	0.78 GO:0031901 early endosome membrane 0.78 GO:0030424 axon 0.76 GO:0005769 early endosome 0.75 GO:0043005 neuron projection 0.74 GO:0010008 endosome membrane 0.72 GO:0045202 synapse 0.72 GO:0005768 endosome 0.72 GO:0000139 Golgi membrane 0.71 GO:0030659 cytoplasmic vesicle membrane 0.71 GO:0120025 plasma membrane bounded cell projection	0.86 EC:3.4.23.- GO:0042500