Queries 4001 to 5000

GO:0004692

tr|T1EPF7|T1EPF7_HELRO
Uncharacterized protein
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tr|T1EPF8|T1EPF8_HELRO
Uncharacterized protein
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tr|T1EPF9|T1EPF9_HELRO
Uncharacterized protein
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0.72	GO:0007093	mitotic cell cycle checkpoint
0.40	GO:0019226	transmission of nerve impulse
0.40	GO:0017182	peptidyl-diphthamide metabolic process
0.40	GO:0042552	myelination
0.40	GO:1900247	regulation of cytoplasmic translational elongation
0.40	GO:0007422	peripheral nervous system development
0.40	GO:0050808	synapse organization
0.40	GO:0007411	axon guidance
0.39	GO:0000398	mRNA splicing, via spliceosome
0.39	GO:0002175	protein localization to paranode region of axon

0.40	GO:0005515	protein binding
0.40	GO:0030248	cellulose binding
0.38	GO:0098631	cell adhesion mediator activity
0.36	GO:0004252	serine-type endopeptidase activity
0.34	GO:0016740	transferase activity

0.71	GO:0016607	nuclear speck
0.41	GO:0070701	mucus layer
0.39	GO:0097454	Schwann cell microvillus
0.39	GO:0101003	ficolin-1-rich granule membrane
0.39	GO:0033010	paranodal junction
0.38	GO:0043194	axon initial segment
0.38	GO:0033268	node of Ranvier
0.38	GO:0033270	paranode region of axon
0.37	GO:0043209	myelin sheath
0.37	GO:0005925	focal adhesion

0.36

GO:0004252

tr|T1EPG0|T1EPG0_HELRO
Uncharacterized protein
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tr|T1EPG1|T1EPG1_HELRO
Uncharacterized protein
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0.44	GO:0007017	microtubule-based process
0.42	GO:0007010	cytoskeleton organization
0.41	GO:0007049	cell cycle
0.41	GO:0006508	proteolysis
0.37	GO:0034968	histone lysine methylation
0.37	GO:0099139	cheating during chimeric sorocarp development
0.36	GO:0051258	protein polymerization
0.36	GO:0043632	modification-dependent macromolecule catabolic process
0.36	GO:0006928	movement of cell or subcellular component
0.36	GO:0044257	cellular protein catabolic process

0.41	GO:0140096	catalytic activity, acting on a protein
0.38	GO:0046872	metal ion binding
0.38	GO:0016787	hydrolase activity
0.37	GO:0016278	lysine N-methyltransferase activity
0.37	GO:0043015	gamma-tubulin binding
0.35	GO:0001104	RNA polymerase II transcription cofactor activity
0.35	GO:0019904	protein domain specific binding
0.35	GO:0008061	chitin binding
0.34	GO:0016491	oxidoreductase activity
0.33	GO:0016301	kinase activity

0.42	GO:0005634	nucleus
0.38	GO:0000775	chromosome, centromeric region
0.37	GO:0000922	spindle pole
0.36	GO:0005815	microtubule organizing center
0.35	GO:0005615	extracellular space
0.34	GO:0043233	organelle lumen
0.33	GO:0043234	protein complex
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.38

GO:0016787

tr|T1EPG2|T1EPG2_HELRO
Uncharacterized protein
Search

0.51	GO:0010951	negative regulation of endopeptidase activity
0.42	GO:1902284	neuron projection extension involved in neuron projection guidance
0.41	GO:0048675	axon extension
0.40	GO:0007411	axon guidance
0.39	GO:0035107	appendage morphogenesis
0.39	GO:0007412	axon target recognition
0.38	GO:0035310	notum cell fate specification
0.38	GO:0071711	basement membrane organization
0.38	GO:0033336	caudal fin development
0.38	GO:0007477	notum development

0.58	GO:0005201	extracellular matrix structural constituent
0.52	GO:0004867	serine-type endopeptidase inhibitor activity
0.43	GO:0030246	carbohydrate binding
0.38	GO:0005154	epidermal growth factor receptor binding
0.37	GO:0008201	heparin binding
0.37	GO:0035091	phosphatidylinositol binding
0.37	GO:0005096	GTPase activator activity
0.37	GO:0042302	structural constituent of cuticle
0.37	GO:0008270	zinc ion binding
0.36	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding

0.70	GO:0005581	collagen trimer
0.52	GO:0005578	proteinaceous extracellular matrix
0.51	GO:0044420	extracellular matrix component
0.43	GO:0042383	sarcolemma
0.40	GO:0005615	extracellular space
0.34	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

tr|T1EPG3|T1EPG3_HELRO
Uncharacterized protein
Search

tr|T1EPG4|T1EPG4_HELRO
Uncharacterized protein
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tr|T1EPG5|T1EPG5_HELRO
Uncharacterized protein
Search

tr|T1EPG6|T1EPG6_HELRO
Uncharacterized protein
Search

tr|T1EPG7|T1EPG7_HELRO
Uncharacterized protein
Search

tr|T1EPG8|T1EPG8_HELRO
Uncharacterized protein
Search

tr|T1EPG9|T1EPG9_HELRO
Uncharacterized protein
Search

0.62	GO:0032259	methylation
0.36	GO:0000154	rRNA modification
0.34	GO:0006898	receptor-mediated endocytosis
0.33	GO:0006768	biotin metabolic process
0.33	GO:0072330	monocarboxylic acid biosynthetic process
0.33	GO:0044260	cellular macromolecule metabolic process
0.33	GO:0044272	sulfur compound biosynthetic process
0.33	GO:0042364	water-soluble vitamin biosynthetic process
0.33	GO:0009108	coenzyme biosynthetic process
0.32	GO:0043604	amide biosynthetic process

0.62	GO:0008168	methyltransferase activity
0.36	GO:0140102	catalytic activity, acting on a rRNA
0.35	GO:0005044	scavenger receptor activity

0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.62

GO:0008168

tr|T1EPH0|T1EPH0_HELRO
Uncharacterized protein
Search

tr|T1EPH1|T1EPH1_HELRO
Uncharacterized protein
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0.41	Glutathione S-transferase 1

0.40	GO:0045087	innate immune response
0.30	GO:0008152	metabolic process

0.62	GO:0004364	glutathione transferase activity
0.44	GO:0005212	structural constituent of eye lens

0.30

GO:0044425

membrane part

0.62

EC:2.5.1.18

GO:0004364

tr|T1EPH2|T1EPH2_HELRO
Uncharacterized protein
Search

tr|T1EPH3|T1EPH3_HELRO
Uncharacterized protein
Search

0.77	GO:0006887	exocytosis
0.50	GO:2000535	regulation of entry of bacterium into host cell
0.34	GO:0015031	protein transport
0.34	GO:0016241	regulation of macroautophagy

0.33

GO:0005515

protein binding

0.79	GO:0000145	exocyst
0.50	GO:0032584	growth cone membrane
0.48	GO:0034451	centriolar satellite
0.37	GO:0090543	Flemming body
0.35	GO:0005829	cytosol
0.34	GO:0097546	ciliary base
0.34	GO:0097731	9+0 non-motile cilium

tr|T1EPH4|T1EPH4_HELRO
Uncharacterized protein
Search

tr|T1EPH5|T1EPH5_HELRO
Uncharacterized protein
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0.51	GO:0051568	histone H3-K4 methylation
0.48	GO:0006429	leucyl-tRNA aminoacylation
0.47	GO:0065007	biological regulation
0.45	GO:0043627	response to estrogen
0.39	GO:0070143	mitochondrial alanyl-tRNA aminoacylation
0.37	GO:0000727	double-strand break repair via break-induced replication
0.37	GO:0048468	cell development
0.37	GO:0006909	phagocytosis
0.37	GO:0006468	protein phosphorylation
0.37	GO:0006928	movement of cell or subcellular component

0.51	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.48	GO:0004823	leucine-tRNA ligase activity
0.46	GO:0140110	transcription regulator activity
0.46	GO:0002161	aminoacyl-tRNA editing activity
0.42	GO:0030554	adenyl nucleotide binding
0.42	GO:0044212	transcription regulatory region DNA binding
0.42	GO:0097367	carbohydrate derivative binding
0.42	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0008144	drug binding
0.41	GO:0046872	metal ion binding

0.49	GO:0035097	histone methyltransferase complex
0.39	GO:0005737	cytoplasm
0.37	GO:0030286	dynein complex
0.37	GO:0031429	box H/ACA snoRNP complex
0.37	GO:0030015	CCR4-NOT core complex
0.36	GO:0000124	SAGA complex
0.36	GO:0035770	ribonucleoprotein granule
0.36	GO:0030687	preribosome, large subunit precursor
0.35	GO:0016514	SWI/SNF complex
0.35	GO:0046695	SLIK (SAGA-like) complex

0.48	EC:6.1.1.4	GO:0004823
0.48	KEGG:R03657	GO:0004823

tr|T1EPH6|T1EPH6_HELRO
Uncharacterized protein
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tr|T1EPH7|T1EPH7_HELRO
Uncharacterized protein
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tr|T1EPH8|T1EPH8_HELRO
Uncharacterized protein
Search

0.44	GO:0007429	secondary branching, open tracheal system
0.43	GO:1903729	regulation of plasma membrane organization
0.43	GO:0007428	primary branching, open tracheal system
0.43	GO:0009997	negative regulation of cardioblast cell fate specification
0.43	GO:0035225	determination of genital disc primordium
0.43	GO:0061320	pericardial nephrocyte differentiation
0.43	GO:0007464	R3/R4 cell fate commitment
0.43	GO:0061331	epithelial cell proliferation involved in Malpighian tubule morphogenesis
0.42	GO:0007426	tracheal outgrowth, open tracheal system
0.42	GO:0048384	retinoic acid receptor signaling pathway

0.43	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.41	GO:0070491	repressing transcription factor binding
0.41	GO:0098531	transcription factor activity, direct ligand regulated sequence-specific DNA binding
0.41	GO:0005096	GTPase activator activity
0.41	GO:0003707	steroid hormone receptor activity
0.41	GO:0043130	ubiquitin binding
0.41	GO:0030674	protein binding, bridging
0.40	GO:0043565	sequence-specific DNA binding
0.39	GO:0044212	transcription regulatory region DNA binding
0.39	GO:0042802	identical protein binding

0.42	GO:0032154	cleavage furrow
0.41	GO:0030014	CCR4-NOT complex
0.41	GO:0005813	centrosome
0.39	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|T1EPH9|T1EPH9_HELRO
Uncharacterized protein
Search

tr|T1EPI0|T1EPI0_HELRO
Uncharacterized protein
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tr|T1EPI1|T1EPI1_HELRO
Uncharacterized protein
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tr|T1EPI2|T1EPI2_HELRO
Uncharacterized protein
Search

CUTC

0.50	Copper homeostasis protein cutC

0.80	GO:0055070	copper ion homeostasis
0.65	GO:0046916	cellular transition metal ion homeostasis
0.34	GO:0051262	protein tetramerization
0.34	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.34	GO:0000256	allantoin catabolic process
0.34	GO:0040025	vulval development
0.34	GO:0018991	oviposition
0.33	GO:0035264	multicellular organism growth
0.33	GO:0032870	cellular response to hormone stimulus
0.33	GO:0046688	response to copper ion

0.72	GO:0005507	copper ion binding
0.34	GO:0004037	allantoicase activity
0.34	GO:0004340	glucokinase activity
0.33	GO:0008514	organic anion transmembrane transporter activity
0.33	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.33	GO:0004497	monooxygenase activity
0.33	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0020037	heme binding
0.33	GO:0005506	iron ion binding

0.45	GO:0005737	cytoplasm
0.34	GO:0046581	intercellular canaliculus
0.34	GO:0016324	apical plasma membrane
0.34	GO:0005730	nucleolus
0.33	GO:0005654	nucleoplasm
0.33	GO:0009986	cell surface
0.33	GO:0005887	integral component of plasma membrane

0.34	EC:3.5.3.4	GO:0004037
0.34	KEGG:R02422	GO:0004037

tr|T1EPI3|T1EPI3_HELRO
Uncharacterized protein
Search

0.55	GO:0007186	G-protein coupled receptor signaling pathway
0.48	GO:0005975	carbohydrate metabolic process
0.41	GO:0009057	macromolecule catabolic process
0.40	GO:0050482	arachidonic acid secretion
0.37	GO:0006644	phospholipid metabolic process
0.36	GO:0019538	protein metabolic process
0.36	GO:0044248	cellular catabolic process
0.35	GO:0043412	macromolecule modification
0.35	GO:0016311	dephosphorylation
0.35	GO:0044260	cellular macromolecule metabolic process

0.55	GO:0030248	cellulose binding
0.55	GO:0004930	G-protein coupled receptor activity
0.44	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.39	GO:0004623	phospholipase A2 activity
0.37	GO:0140096	catalytic activity, acting on a protein
0.35	GO:0046872	metal ion binding
0.35	GO:0016791	phosphatase activity
0.35	GO:0017171	serine hydrolase activity
0.34	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.34	GO:0016301	kinase activity

0.48	GO:0005576	extracellular region
0.38	GO:0005581	collagen trimer
0.30	GO:0016020	membrane

0.44

EC:3.2.1

GO:0004553

tr|T1EPI4|T1EPI4_HELRO
Uncharacterized protein
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tr|T1EPI5|T1EPI5_HELRO
Uncharacterized protein
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tr|T1EPI6|T1EPI6_HELRO
Uncharacterized protein
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tr|T1EPI7|T1EPI7_HELRO
Uncharacterized protein
Search

0.56	GO:0006030	chitin metabolic process
0.45	GO:0016998	cell wall macromolecule catabolic process
0.44	GO:0009253	peptidoglycan catabolic process
0.41	GO:0006955	immune response
0.41	GO:0006898	receptor-mediated endocytosis
0.40	GO:0016569	covalent chromatin modification
0.40	GO:0019230	proprioception
0.40	GO:0007162	negative regulation of cell adhesion
0.39	GO:0009250	glucan biosynthetic process
0.38	GO:0050954	sensory perception of mechanical stimulus

0.57	GO:0008061	chitin binding
0.45	GO:0003796	lysozyme activity
0.43	GO:0005044	scavenger receptor activity
0.42	GO:0001871	pattern binding
0.40	GO:0030246	carbohydrate binding
0.40	GO:0046527	glucosyltransferase activity
0.40	GO:0019992	diacylglycerol binding
0.38	GO:0005515	protein binding
0.38	GO:0008270	zinc ion binding
0.36	GO:0008237	metallopeptidase activity

0.43	GO:0005576	extracellular region
0.40	GO:0071683	sensory dendrite
0.37	GO:0005634	nucleus
0.37	GO:0005856	cytoskeleton
0.35	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.45

EC:3.2.1.17

GO:0003796

tr|T1EPI8|T1EPI8_HELRO
Uncharacterized protein
Search

tr|T1EPI9|T1EPI9_HELRO
Uncharacterized protein
Search

tr|T1EPJ0|T1EPJ0_HELRO
Uncharacterized protein
Search

tr|T1EPJ1|T1EPJ1_HELRO
Uncharacterized protein
Search

tr|T1EPJ2|T1EPJ2_HELRO
Uncharacterized protein
Search

0.41	GO:0071897	DNA biosynthetic process
0.41	GO:0006413	translational initiation
0.40	GO:0006260	DNA replication
0.38	GO:0007018	microtubule-based movement
0.37	GO:0065007	biological regulation
0.37	GO:0036211	protein modification process
0.37	GO:0006796	phosphate-containing compound metabolic process
0.35	GO:0071840	cellular component organization or biogenesis
0.35	GO:0016072	rRNA metabolic process
0.35	GO:0032366	intracellular sterol transport

0.42	GO:0003924	GTPase activity
0.42	GO:0003887	DNA-directed DNA polymerase activity
0.41	GO:0005525	GTP binding
0.41	GO:0003743	translation initiation factor activity
0.40	GO:0004075	biotin carboxylase activity
0.38	GO:0003677	DNA binding
0.38	GO:0003700	DNA binding transcription factor activity
0.38	GO:0016301	kinase activity
0.38	GO:0046872	metal ion binding
0.38	GO:0003777	microtubule motor activity

0.37	GO:0032040	small-subunit processome
0.37	GO:0043231	intracellular membrane-bounded organelle
0.36	GO:0009343	biotin carboxylase complex
0.35	GO:0012505	endomembrane system
0.35	GO:0031410	cytoplasmic vesicle
0.35	GO:0046658	anchored component of plasma membrane
0.34	GO:0044448	cell cortex part
0.34	GO:0044446	intracellular organelle part
0.34	GO:0042575	DNA polymerase complex
0.34	GO:0012506	vesicle membrane

0.42	EC:2.7.7.7	GO:0003887
0.34	KEGG:R08715	GO:0052761

tr|T1EPJ3|T1EPJ3_HELRO
Uncharacterized protein
Search

0.44	GO:0070407	oxidation-dependent protein catabolic process
0.44	GO:0090296	regulation of mitochondrial DNA replication
0.43	GO:0051131	chaperone-mediated protein complex assembly
0.42	GO:0006515	protein quality control for misfolded or incompletely synthesized proteins
0.41	GO:0016567	protein ubiquitination
0.41	GO:0034599	cellular response to oxidative stress
0.40	GO:0023051	regulation of signaling
0.40	GO:1903474	anchoring of the mitotic actomyosin contractile ring to the plasma membrane
0.39	GO:0007218	neuropeptide signaling pathway
0.39	GO:0010951	negative regulation of endopeptidase activity

0.45	GO:0003682	chromatin binding
0.44	GO:0001784	phosphotyrosine residue binding
0.42	GO:0005509	calcium ion binding
0.41	GO:0004176	ATP-dependent peptidase activity
0.41	GO:0004842	ubiquitin-protein transferase activity
0.41	GO:0043565	sequence-specific DNA binding
0.40	GO:0004983	neuropeptide Y receptor activity
0.39	GO:0004252	serine-type endopeptidase activity
0.39	GO:0004867	serine-type endopeptidase inhibitor activity
0.37	GO:0030246	carbohydrate binding

0.41	GO:0005759	mitochondrial matrix
0.39	GO:0005581	collagen trimer
0.38	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.39	EC:3.4.21	GO:0004252
0.41	KEGG:R03876	GO:0004842

tr|T1EPJ4|T1EPJ4_HELRO
Uncharacterized protein
Search

tr|T1EPJ5|T1EPJ5_HELRO
Uncharacterized protein
Search

tr|T1EPJ6|T1EPJ6_HELRO
Uncharacterized protein
Search

tr|T1EPJ7|T1EPJ7_HELRO
Uncharacterized protein
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tr|T1EPJ8|T1EPJ8_HELRO
Uncharacterized protein
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tr|T1EPJ9|T1EPJ9_HELRO
Uncharacterized protein
Search

0.63	GO:0006468	protein phosphorylation
0.42	GO:0072577	endothelial cell apoptotic process
0.41	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway
0.41	GO:0060235	lens induction in camera-type eye
0.41	GO:0061072	iris morphogenesis
0.41	GO:0097191	extrinsic apoptotic signaling pathway
0.41	GO:0060059	embryonic retina morphogenesis in camera-type eye
0.41	GO:0010842	retina layer formation
0.40	GO:0048596	embryonic camera-type eye morphogenesis
0.40	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0003677	DNA binding
0.34	GO:0004527	exonuclease activity

0.42	GO:0016605	PML body
0.39	GO:0005813	centrosome
0.39	GO:0016607	nuclear speck
0.39	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|T1EPK0|T1EPK0_HELRO
Uncharacterized protein
Search

0.63

GO:0006468

protein phosphorylation

0.64	GO:0004672	protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

tr|T1EPK1|T1EPK1_HELRO
Uncharacterized protein
Search

tr|T1EPK2|T1EPK2_HELRO
Uncharacterized protein
Search

0.47	GO:0016567	protein ubiquitination
0.41	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.41	GO:0010468	regulation of gene expression
0.41	GO:0051171	regulation of nitrogen compound metabolic process
0.41	GO:0080090	regulation of primary metabolic process
0.39	GO:0006470	protein dephosphorylation
0.39	GO:0007275	multicellular organism development
0.38	GO:0006996	organelle organization
0.38	GO:0022402	cell cycle process
0.37	GO:0048518	positive regulation of biological process

0.47	GO:0004842	ubiquitin-protein transferase activity
0.41	GO:0140110	transcription regulator activity
0.40	GO:0004722	protein serine/threonine phosphatase activity
0.40	GO:0046872	metal ion binding
0.39	GO:0003676	nucleic acid binding
0.38	GO:0005515	protein binding
0.37	GO:0003987	acetate-CoA ligase activity
0.37	GO:0005096	GTPase activator activity
0.36	GO:0003682	chromatin binding
0.36	GO:0004674	protein serine/threonine kinase activity

0.43	GO:0005634	nucleus
0.39	GO:0031592	centrosomal corona
0.39	GO:0036464	cytoplasmic ribonucleoprotein granule
0.38	GO:0030015	CCR4-NOT core complex
0.36	GO:0070013	intracellular organelle lumen
0.36	GO:0005700	polytene chromosome
0.36	GO:0000796	condensin complex
0.35	GO:0005615	extracellular space
0.35	GO:1990234	transferase complex
0.34	GO:0005667	transcription factor complex

0.37	EC:6.2.1.1	GO:0003987
0.47	KEGG:R03876	GO:0004842

tr|T1EPK3|T1EPK3_HELRO
Uncharacterized protein
Search

tr|T1EPK4|T1EPK4_HELRO
Uncharacterized protein
Search

0.71	GO:0071805	potassium ion transmembrane transport
0.60	GO:0010469	regulation of receptor activity
0.49	GO:0030322	stabilization of membrane potential
0.47	GO:0060047	heart contraction
0.40	GO:0051481	negative regulation of cytosolic calcium ion concentration
0.40	GO:0071294	cellular response to zinc ion
0.39	GO:0090102	cochlea development
0.39	GO:0071456	cellular response to hypoxia
0.38	GO:0007420	brain development
0.36	GO:0042493	response to drug

0.74	GO:0005267	potassium channel activity
0.62	GO:0008083	growth factor activity
0.59	GO:0022843	voltage-gated cation channel activity
0.51	GO:0022842	narrow pore channel activity
0.47	GO:0044548	S100 protein binding
0.43	GO:0046982	protein heterodimerization activity
0.39	GO:0008022	protein C-terminus binding
0.37	GO:0042803	protein homodimerization activity
0.34	GO:0005200	structural constituent of cytoskeleton
0.33	GO:0003924	GTPase activity

0.59	GO:0005615	extracellular space
0.42	GO:0005887	integral component of plasma membrane
0.36	GO:0036195	muscle cell projection membrane
0.35	GO:0055120	striated muscle dense body
0.34	GO:0005874	microtubule
0.32	GO:0005634	nucleus

tr|T1EPK5|T1EPK5_HELRO
Uncharacterized protein
Search

0.69	GO:0006955	immune response
0.68	GO:0006898	receptor-mediated endocytosis
0.54	GO:0030505	inorganic diphosphate transport
0.54	GO:0009143	nucleoside triphosphate catabolic process
0.53	GO:0030730	sequestering of triglyceride
0.53	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process
0.53	GO:0045719	negative regulation of glycogen biosynthetic process
0.53	GO:0031953	negative regulation of protein autophosphorylation
0.52	GO:0046325	negative regulation of glucose import
0.51	GO:0046627	negative regulation of insulin receptor signaling pathway

0.76	GO:0005044	scavenger receptor activity
0.74	GO:0030247	polysaccharide binding
0.59	GO:0004528	phosphodiesterase I activity
0.54	GO:0004551	nucleotide diphosphatase activity
0.52	GO:0047429	nucleoside-triphosphate diphosphatase activity
0.52	GO:0005158	insulin receptor binding
0.51	GO:0046872	metal ion binding
0.49	GO:0003676	nucleic acid binding
0.47	GO:0042803	protein homodimerization activity
0.41	GO:0004622	lysophospholipase activity

0.47	GO:0009986	cell surface
0.46	GO:0005615	extracellular space
0.46	GO:0048471	perinuclear region of cytoplasm
0.40	GO:0005886	plasma membrane
0.37	GO:0005765	lysosomal membrane
0.35	GO:0097441	basal dendrite
0.35	GO:0097440	apical dendrite
0.34	GO:1903561	extracellular vesicle
0.34	GO:0043025	neuronal cell body
0.34	GO:0045202	synapse

0.59

EC:3.1.4.1

GO:0004528

tr|T1EPK6|T1EPK6_HELRO
Uncharacterized protein
Search

tr|T1EPK7|T1EPK7_HELRO
Uncharacterized protein
Search

tr|T1EPK8|T1EPK8_HELRO
Uncharacterized protein
Search

tr|T1EPK9|T1EPK9_HELRO
Uncharacterized protein
Search

tr|T1EPL0|T1EPL0_HELRO
Uncharacterized protein
Search

0.58	GO:0007018	microtubule-based movement
0.38	GO:0006338	chromatin remodeling
0.38	GO:0006888	ER to Golgi vesicle-mediated transport
0.37	GO:0006886	intracellular protein transport
0.36	GO:0006281	DNA repair
0.35	GO:0006351	transcription, DNA-templated

0.59	GO:0003777	microtubule motor activity
0.59	GO:0008017	microtubule binding
0.46	GO:0030554	adenyl nucleotide binding
0.45	GO:0032555	purine ribonucleotide binding
0.45	GO:0008144	drug binding
0.45	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0016887	ATPase activity
0.36	GO:0008270	zinc ion binding
0.35	GO:0003676	nucleic acid binding

0.43	GO:0015630	microtubule cytoskeleton
0.43	GO:0044430	cytoskeletal part
0.42	GO:0099512	supramolecular fiber
0.39	GO:0005634	nucleus
0.39	GO:0030127	COPII vesicle coat
0.38	GO:0033202	DNA helicase complex
0.37	GO:0000785	chromatin
0.37	GO:0031974	membrane-enclosed lumen
0.36	GO:1904949	ATPase complex
0.30	GO:0031224	intrinsic component of membrane

0.37

EC:3.6.1.3

GO:0016887

tr|T1EPL1|T1EPL1_HELRO
Uncharacterized protein
Search

0.39	GO:0036211	protein modification process
0.39	GO:0044267	cellular protein metabolic process
0.39	GO:0065007	biological regulation
0.38	GO:0051716	cellular response to stimulus
0.38	GO:0051641	cellular localization
0.37	GO:0023052	signaling
0.37	GO:0007154	cell communication
0.37	GO:0071702	organic substance transport
0.37	GO:0033036	macromolecule localization
0.37	GO:0099120	socially cooperative development

0.39	GO:0003676	nucleic acid binding
0.39	GO:0043168	anion binding
0.39	GO:0017076	purine nucleotide binding
0.39	GO:0032553	ribonucleotide binding
0.39	GO:0140096	catalytic activity, acting on a protein
0.39	GO:0003924	GTPase activity
0.38	GO:0032550	purine ribonucleoside binding
0.38	GO:0098772	molecular function regulator
0.37	GO:0140110	transcription regulator activity
0.37	GO:0008144	drug binding

0.40	GO:0044432	endoplasmic reticulum part
0.40	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.39	GO:0005634	nucleus
0.39	GO:0031984	organelle subcompartment
0.36	GO:0032991	macromolecular complex
0.35	GO:0043232	intracellular non-membrane-bounded organelle
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0020011	apicoplast
0.34	GO:0098805	whole membrane
0.34	GO:0098588	bounding membrane of organelle

0.37	EC:2.7.1	GO:0016773
0.35	KEGG:R01220	GO:0004488

tr|T1EPL2|T1EPL2_HELRO
Uncharacterized protein
Search

0.57	GO:0071460	cellular response to cell-matrix adhesion
0.56	GO:1901329	regulation of odontoblast differentiation
0.56	GO:0097187	dentinogenesis
0.56	GO:0071895	odontoblast differentiation
0.55	GO:0070175	positive regulation of enamel mineralization
0.55	GO:0048820	hair follicle maturation
0.54	GO:0071549	cellular response to dexamethasone stimulus
0.53	GO:0031214	biomineral tissue development
0.51	GO:0009612	response to mechanical stimulus
0.51	GO:0051216	cartilage development

0.51	GO:0005518	collagen binding
0.46	GO:0032555	purine ribonucleotide binding
0.46	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0030554	adenyl nucleotide binding
0.44	GO:0008144	drug binding
0.41	GO:0003924	GTPase activity
0.41	GO:0032550	purine ribonucleoside binding
0.41	GO:0019001	guanyl nucleotide binding
0.40	GO:0003723	RNA binding

0.48	GO:0005578	proteinaceous extracellular matrix
0.48	GO:0005634	nucleus
0.45	GO:0031974	membrane-enclosed lumen
0.42	GO:0043232	intracellular non-membrane-bounded organelle
0.41	GO:0044446	intracellular organelle part
0.40	GO:0005886	plasma membrane
0.38	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

tr|T1EPL3|T1EPL3_HELRO
Uncharacterized protein
Search

tr|T1EPL4|T1EPL4_HELRO
Uncharacterized protein
Search

tr|T1EPL5|T1EPL5_HELRO
Uncharacterized protein
Search

tr|T1EPL6|T1EPL6_HELRO
Uncharacterized protein
Search

tr|T1EPL7|T1EPL7_HELRO
Uncharacterized protein
Search

tr|T1EPL8|T1EPL8_HELRO
Uncharacterized protein
Search

tr|T1EPL9|T1EPL9_HELRO
Uncharacterized protein
Search

tr|T1EPM0|T1EPM0_HELRO
Uncharacterized protein
Search

tr|T1EPM1|T1EPM1_HELRO
Uncharacterized protein
Search

tr|T1EPM2|T1EPM2_HELRO
Uncharacterized protein
Search

tr|T1EPM3|T1EPM3_HELRO
Uncharacterized protein
Search

tr|T1EPM4|T1EPM4_HELRO
Uncharacterized protein
Search

0.43	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.42	GO:0016266	O-glycan processing

0.44

GO:0030197

extracellular matrix constituent, lubricant activity

0.42	GO:0005796	Golgi lumen
0.38	GO:0005576	extracellular region
0.35	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1EPM5|T1EPM5_HELRO
Uncharacterized protein
Search

tr|T1EPM6|T1EPM6_HELRO
Uncharacterized protein
Search

0.51	GO:0035556	intracellular signal transduction
0.36	GO:0055085	transmembrane transport

0.51	GO:0046872	metal ion binding
0.36	GO:0022857	transmembrane transporter activity

0.40	GO:0005622	intracellular
0.30	GO:0044425	membrane part

tr|T1EPM7|T1EPM7_HELRO
ATP-dependent DNA helicase
Search

0.10	ATP-dependent DNA helicase

tr|T1EPM8|T1EPM8_HELRO
Uncharacterized protein
Search

tr|T1EPM9|T1EPM9_HELRO
Uncharacterized protein
Search

tr|T1EPN0|T1EPN0_HELRO
Uncharacterized protein
Search

0.45	GO:2001141	regulation of RNA biosynthetic process
0.45	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.45	GO:0010468	regulation of gene expression
0.41	GO:0006904	vesicle docking involved in exocytosis
0.40	GO:0006413	translational initiation
0.39	GO:0006422	aspartyl-tRNA aminoacylation
0.38	GO:0034968	histone lysine methylation
0.36	GO:0032774	RNA biosynthetic process
0.36	GO:0060912	cardiac cell fate specification
0.36	GO:0016579	protein deubiquitination

0.52	GO:0046982	protein heterodimerization activity
0.47	GO:0003700	DNA binding transcription factor activity
0.43	GO:0003677	DNA binding
0.40	GO:0003743	translation initiation factor activity
0.39	GO:0004815	aspartate-tRNA ligase activity
0.38	GO:0018024	histone-lysine N-methyltransferase activity
0.37	GO:0000829	inositol heptakisphosphate kinase activity
0.37	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.37	GO:0030554	adenyl nucleotide binding
0.36	GO:0046872	metal ion binding

0.56	GO:0016602	CCAAT-binding factor complex
0.37	GO:0005694	chromosome
0.35	GO:0090568	nuclear transcriptional repressor complex
0.35	GO:0000118	histone deacetylase complex
0.35	GO:0005737	cytoplasm
0.35	GO:0005618	cell wall
0.34	GO:0005576	extracellular region
0.34	GO:1904949	ATPase complex
0.30	GO:0016020	membrane

0.39

EC:6.1.1.12

GO:0004815

tr|T1EPN1|T1EPN1_HELRO
Uncharacterized protein
Search

tr|T1EPN2|T1EPN2_HELRO
Uncharacterized protein
Search

tr|T1EPN3|T1EPN3_HELRO
Uncharacterized protein
Search

tr|T1EPN4|T1EPN4_HELRO
Uncharacterized protein
Search

0.54	GO:0006886	intracellular protein transport
0.49	GO:0006413	translational initiation
0.41	GO:0050790	regulation of catalytic activity

0.61	GO:0017137	Rab GTPase binding
0.49	GO:0003743	translation initiation factor activity
0.47	GO:0008201	heparin binding
0.47	GO:0003924	GTPase activity
0.46	GO:0032550	purine ribonucleoside binding
0.46	GO:0019001	guanyl nucleotide binding
0.44	GO:0030695	GTPase regulator activity
0.41	GO:0003677	DNA binding
0.41	GO:0046872	metal ion binding
0.41	GO:0032555	purine ribonucleotide binding

0.40	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|T1EPN5|T1EPN5_HELRO
Uncharacterized protein
Search

tr|T1EPN6|T1EPN6_HELRO
Uncharacterized protein
Search

tr|T1EPN7|T1EPN7_HELRO
Uncharacterized protein
Search

tr|T1EPN8|T1EPN8_HELRO
Uncharacterized protein
Search

0.42	GO:0016570	histone modification
0.41	GO:0032958	inositol phosphate biosynthetic process
0.40	GO:2001141	regulation of RNA biosynthetic process
0.40	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.40	GO:0010468	regulation of gene expression
0.40	GO:0006476	protein deacetylation
0.39	GO:0006351	transcription, DNA-templated
0.38	GO:0018393	internal peptidyl-lysine acetylation
0.38	GO:0099120	socially cooperative development
0.37	GO:0006629	lipid metabolic process

0.41	GO:0032041	NAD-dependent histone deacetylase activity (H3-K14 specific)
0.39	GO:0003700	DNA binding transcription factor activity
0.38	GO:0004402	histone acetyltransferase activity
0.38	GO:0003676	nucleic acid binding
0.38	GO:0046872	metal ion binding
0.37	GO:0016301	kinase activity
0.37	GO:0017111	nucleoside-triphosphatase activity
0.37	GO:0017076	purine nucleotide binding
0.37	GO:0097367	carbohydrate derivative binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding

0.42	GO:0005634	nucleus
0.38	GO:0070013	intracellular organelle lumen
0.38	GO:0031248	protein acetyltransferase complex
0.37	GO:0043234	protein complex
0.36	GO:0044446	intracellular organelle part
0.35	GO:0005844	polysome
0.34	GO:0020036	Maurer's cleft
0.33	GO:0000428	DNA-directed RNA polymerase complex
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.33	GO:0012505	endomembrane system

0.41

EC:3.5.1.98

GO:0032041

tr|T1EPN9|T1EPN9_HELRO
Uncharacterized protein
Search

tr|T1EPP0|T1EPP0_HELRO
Uncharacterized protein
Search

tr|T1EPP1|T1EPP1_HELRO
Uncharacterized protein
Search

tr|T1EPP2|T1EPP2_HELRO
Uncharacterized protein
Search

tr|T1EPP3|T1EPP3_HELRO
Uncharacterized protein
Search

tr|T1EPP4|T1EPP4_HELRO
Uncharacterized protein
Search

0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.52	GO:0008344	adult locomotory behavior
0.48	GO:0008345	larval locomotory behavior
0.47	GO:0002209	behavioral defense response
0.33	GO:0035556	intracellular signal transduction
0.33	GO:0006030	chitin metabolic process
0.32	GO:0005975	carbohydrate metabolic process

0.78	GO:0008528	G-protein coupled peptide receptor activity
0.33	GO:0008061	chitin binding
0.32	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.32	GO:0003723	RNA binding

0.45	GO:0005887	integral component of plasma membrane
0.32	GO:0005576	extracellular region
0.32	GO:0005622	intracellular

0.32

EC:3.2.1

GO:0004553

tr|T1EPP5|T1EPP5_HELRO
Uncharacterized protein
Search

tr|T1EPP6|T1EPP6_HELRO
Uncharacterized protein
Search

tr|T1EPP7|T1EPP7_HELRO
Uncharacterized protein
Search

0.45	GO:0006325	chromatin organization
0.42	GO:0044085	cellular component biogenesis
0.42	GO:0006396	RNA processing
0.41	GO:0016072	rRNA metabolic process
0.41	GO:0051641	cellular localization
0.40	GO:0031323	regulation of cellular metabolic process
0.40	GO:0051171	regulation of nitrogen compound metabolic process
0.40	GO:0060255	regulation of macromolecule metabolic process
0.40	GO:0080090	regulation of primary metabolic process
0.40	GO:0071824	protein-DNA complex subunit organization

0.42	GO:0003723	RNA binding
0.41	GO:0005515	protein binding
0.39	GO:0098772	molecular function regulator
0.39	GO:0003682	chromatin binding
0.38	GO:0046872	metal ion binding
0.38	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity
0.38	GO:0140096	catalytic activity, acting on a protein
0.37	GO:0097367	carbohydrate derivative binding
0.37	GO:0008144	drug binding
0.37	GO:0030554	adenyl nucleotide binding

0.48	GO:0005634	nucleus
0.44	GO:0070013	intracellular organelle lumen
0.42	GO:0043232	intracellular non-membrane-bounded organelle
0.42	GO:0044446	intracellular organelle part
0.40	GO:0032991	macromolecular complex
0.36	GO:0005737	cytoplasm
0.35	GO:0005578	proteinaceous extracellular matrix
0.35	GO:0012505	endomembrane system
0.35	GO:0031090	organelle membrane
0.34	GO:0005615	extracellular space

0.37	EC:6	GO:0016874
0.35	KEGG:R03269	GO:0004633

tr|T1EPP8|T1EPP8_HELRO
Uncharacterized protein
Search

0.46	GO:0001522	pseudouridine synthesis
0.41	GO:0060255	regulation of macromolecule metabolic process
0.41	GO:0031323	regulation of cellular metabolic process
0.41	GO:0051171	regulation of nitrogen compound metabolic process
0.41	GO:0080090	regulation of primary metabolic process
0.41	GO:0009889	regulation of biosynthetic process
0.40	GO:0014018	neuroblast fate specification
0.40	GO:0007350	blastoderm segmentation
0.38	GO:0048477	oogenesis
0.38	GO:0010467	gene expression

0.46	GO:0009982	pseudouridine synthase activity
0.45	GO:0003676	nucleic acid binding
0.43	GO:0008270	zinc ion binding
0.40	GO:0003700	DNA binding transcription factor activity
0.40	GO:0005515	protein binding
0.40	GO:0004491	methylmalonate-semialdehyde dehydrogenase (acylating) activity
0.38	GO:0030554	adenyl nucleotide binding
0.38	GO:0016817	hydrolase activity, acting on acid anhydrides
0.38	GO:0097367	carbohydrate derivative binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding

0.46	GO:0005634	nucleus
0.37	GO:0008076	voltage-gated potassium channel complex
0.36	GO:1990234	transferase complex
0.36	GO:0000938	GARP complex
0.35	GO:0005700	polytene chromosome
0.35	GO:0005829	cytosol
0.35	GO:0017053	transcriptional repressor complex
0.35	GO:0005813	centrosome
0.35	GO:0005667	transcription factor complex
0.34	GO:0070013	intracellular organelle lumen

0.46

EC:5.4.99.12

GO:0009982

tr|T1EPP9|T1EPP9_HELRO
Uncharacterized protein
Search

tr|T1EPQ0|T1EPQ0_HELRO
Uncharacterized protein
Search

tr|T1EPQ1|T1EPQ1_HELRO
Uncharacterized protein
Search

0.76	GO:0007339	binding of sperm to zona pellucida
0.51	GO:0007018	microtubule-based movement
0.51	GO:0048309	endoplasmic reticulum inheritance
0.50	GO:0007533	mating type switching
0.49	GO:0008298	intracellular mRNA localization

0.52	GO:0003777	microtubule motor activity
0.52	GO:0008017	microtubule binding
0.51	GO:0003779	actin binding
0.50	GO:0000146	microfilament motor activity
0.46	GO:0032403	protein complex binding
0.45	GO:0030554	adenyl nucleotide binding
0.44	GO:0032555	purine ribonucleotide binding
0.44	GO:0008144	drug binding
0.44	GO:0035639	purine ribonucleoside triphosphate binding

0.53	GO:0016459	myosin complex
0.50	GO:0031941	filamentous actin
0.49	GO:0005934	cellular bud tip
0.30	GO:0016020	membrane

tr|T1EPQ2|T1EPQ2_HELRO
Uncharacterized protein
Search

tr|T1EPQ3|T1EPQ3_HELRO
Uncharacterized protein
Search

tr|T1EPQ4|T1EPQ4_HELRO
Uncharacterized protein
Search

tr|T1EPQ5|T1EPQ5_HELRO
Uncharacterized protein
Search

tr|T1EPQ6|T1EPQ6_HELRO
Uncharacterized protein
Search

tr|T1EPQ7|T1EPQ7_HELRO
Uncharacterized protein
Search

tr|T1EPQ8|T1EPQ8_HELRO
ATP-dependent DNA helicase
Search

0.18	ATP-dependent DNA helicase

0.78	GO:0000723	telomere maintenance
0.78	GO:0000002	mitochondrial genome maintenance
0.70	GO:0032392	DNA geometric change
0.65	GO:0006281	DNA repair
0.64	GO:0006310	DNA recombination
0.56	GO:0032211	negative regulation of telomere maintenance via telomerase
0.55	GO:0051974	negative regulation of telomerase activity
0.44	GO:0071932	replication fork reversal
0.43	GO:1905465	regulation of G-quadruplex DNA unwinding
0.42	GO:1903469	removal of RNA primer involved in mitotic DNA replication

0.78	GO:0043141	ATP-dependent 5'-3' DNA helicase activity
0.58	GO:0051880	G-quadruplex DNA binding
0.56	GO:0010521	telomerase inhibitor activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0017116	single-stranded DNA-dependent ATP-dependent DNA helicase activity
0.38	GO:0008270	zinc ion binding
0.37	GO:0003697	single-stranded DNA binding
0.33	GO:0102499	SHG alpha-glucan phosphorylase activity

0.59	GO:0005634	nucleus
0.58	GO:0005739	mitochondrion
0.45	GO:0031933	telomeric heterochromatin
0.44	GO:0005657	replication fork
0.41	GO:0043233	organelle lumen
0.41	GO:0033553	rDNA heterochromatin
0.40	GO:0035861	site of double-strand break
0.35	GO:0031967	organelle envelope
0.35	GO:0031090	organelle membrane
0.33	GO:0032993	protein-DNA complex

0.78

EC:3.6.1

GO:0043141

tr|T1EPQ9|T1EPQ9_HELRO
Uncharacterized protein
Search

0.62	Actin depolymerizing factor

0.83	GO:0030042	actin filament depolymerization
0.41	GO:0030833	regulation of actin filament polymerization
0.41	GO:0071846	actin filament debranching
0.41	GO:1904617	negative regulation of actin binding
0.41	GO:1904529	regulation of actin filament binding
0.40	GO:1903475	mitotic actomyosin contractile ring assembly
0.39	GO:0032273	positive regulation of protein polymerization
0.39	GO:1902905	positive regulation of supramolecular fiber organization
0.39	GO:0051495	positive regulation of cytoskeleton organization
0.38	GO:0032272	negative regulation of protein polymerization

0.74	GO:0003779	actin binding
0.38	GO:0032403	protein complex binding
0.35	GO:0005509	calcium ion binding

0.73	GO:0015629	actin cytoskeleton
0.40	GO:0031097	medial cortex
0.40	GO:0070938	contractile ring
0.39	GO:0061645	endocytic patch
0.39	GO:0030863	cortical cytoskeleton
0.37	GO:0044430	cytoskeletal part
0.36	GO:0055044	symplast
0.35	GO:0005911	cell-cell junction
0.35	GO:0005829	cytosol
0.34	GO:0009507	chloroplast

tr|T1EPR0|T1EPR0_HELRO
Uncharacterized protein
Search

0.63	GO:0008270	zinc ion binding
0.51	GO:0003676	nucleic acid binding

tr|T1EPR1|T1EPR1_HELRO
Uncharacterized protein
Search

tr|T1EPR2|T1EPR2_HELRO
Uncharacterized protein
Search

tr|T1EPR3|T1EPR3_HELRO
Uncharacterized protein
Search

tr|T1EPR4|T1EPR4_HELRO
Uncharacterized protein
Search

tr|T1EPR5|T1EPR5_HELRO
Uncharacterized protein
Search

tr|T1EPR6|T1EPR6_HELRO
Uncharacterized protein
Search

0.67	GO:0090084	negative regulation of inclusion body assembly
0.65	GO:0045109	intermediate filament organization
0.63	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.61	GO:0032781	positive regulation of ATPase activity
0.60	GO:0060715	syncytiotrophoblast cell differentiation involved in labyrinthine layer development
0.58	GO:0060710	chorio-allantoic fusion
0.58	GO:0060717	chorion development
0.57	GO:0032880	regulation of protein localization
0.53	GO:0006457	protein folding
0.53	GO:0030198	extracellular matrix organization

0.61	GO:0001671	ATPase activator activity
0.59	GO:0031072	heat shock protein binding
0.58	GO:0051087	chaperone binding
0.55	GO:0051082	unfolded protein binding
0.51	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism
0.43	GO:0042802	identical protein binding
0.41	GO:0003677	DNA binding
0.40	GO:0044183	protein binding involved in protein folding
0.36	GO:0003735	structural constituent of ribosome

0.67	GO:0030018	Z disc
0.67	GO:0048471	perinuclear region of cytoplasm
0.56	GO:0005634	nucleus
0.53	GO:0031974	membrane-enclosed lumen
0.53	GO:0005829	cytosol
0.48	GO:0044446	intracellular organelle part
0.37	GO:0012505	endomembrane system
0.36	GO:0005840	ribosome
0.35	GO:0031975	envelope
0.30	GO:0016020	membrane

tr|T1EPR7|T1EPR7_HELRO
Uncharacterized protein
Search

tr|T1EPR8|T1EPR8_HELRO
Uncharacterized protein
Search

tr|T1EPR9|T1EPR9_HELRO
Uncharacterized protein
Search

0.33

GO:0007186

G-protein coupled receptor signaling pathway

0.33	GO:0004871	signal transducer activity
0.32	GO:0016740	transferase activity

0.34	GO:1905360	GTPase complex
0.34	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.33	GO:0012505	endomembrane system
0.33	GO:0098797	plasma membrane protein complex
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016740

tr|T1EPS0|T1EPS0_HELRO
Uncharacterized protein
Search

0.65	GO:0007018	microtubule-based movement
0.54	GO:0006278	RNA-dependent DNA biosynthetic process

0.66	GO:0003777	microtubule motor activity
0.66	GO:0008017	microtubule binding
0.54	GO:0003964	RNA-directed DNA polymerase activity
0.50	GO:0030554	adenyl nucleotide binding
0.49	GO:0097367	carbohydrate derivative binding
0.49	GO:0008144	drug binding
0.49	GO:0035639	purine ribonucleoside triphosphate binding

0.54

GO:0003964

tr|T1EPS1|T1EPS1_HELRO
Uncharacterized protein
Search

tr|T1EPS2|T1EPS2_HELRO
Uncharacterized protein
Search

tr|T1EPS3|T1EPS3_HELRO
Uncharacterized protein
Search

tr|T1EPS4|T1EPS4_HELRO
Uncharacterized protein
Search

tr|T1EPS5|T1EPS5_HELRO
Uncharacterized protein
Search

0.53

GO:0051568

histone H3-K4 methylation

0.54	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.49	GO:0003676	nucleic acid binding
0.41	GO:0046872	metal ion binding

0.52

GO:0035097

histone methyltransferase complex

tr|T1EPS6|T1EPS6_HELRO
Uncharacterized protein
Search

tr|T1EPS7|T1EPS7_HELRO
Uncharacterized protein
Search

0.44	GO:0051568	histone H3-K4 methylation
0.39	GO:0006508	proteolysis

0.50	GO:0003676	nucleic acid binding
0.45	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.41	GO:0070001	aspartic-type peptidase activity
0.40	GO:0004175	endopeptidase activity
0.37	GO:0046872	metal ion binding

0.43	GO:0035097	histone methyltransferase complex
0.30	GO:0031224	intrinsic component of membrane

tr|T1EPS8|T1EPS8_HELRO
Uncharacterized protein
Search

tr|T1EPS9|T1EPS9_HELRO
Uncharacterized protein
Search

tr|T1EPT0|T1EPT0_HELRO
Uncharacterized protein
Search

tr|T1EPT1|T1EPT1_HELRO
Uncharacterized protein
Search

tr|T1EPT2|T1EPT2_HELRO
Uncharacterized protein
Search

tr|T1EPT3|T1EPT3_HELRO
Uncharacterized protein
Search

tr|T1EPT4|T1EPT4_HELRO
Uncharacterized protein
Search

tr|T1EPT5|T1EPT5_HELRO
Uncharacterized protein
Search

tr|T1EPT6|T1EPT6_HELRO
Uncharacterized protein
Search

tr|T1EPT7|T1EPT7_HELRO
Uncharacterized protein
Search

tr|T1EPT8|T1EPT8_HELRO
Uncharacterized protein
Search

tr|T1EPT9|T1EPT9_HELRO
Uncharacterized protein
Search

tr|T1EPU0|T1EPU0_HELRO
Uncharacterized protein
Search

tr|T1EPU1|T1EPU1_HELRO
Uncharacterized protein
Search

tr|T1EPU2|T1EPU2_HELRO
Uncharacterized protein
Search

tr|T1EPU3|T1EPU3_HELRO
Uncharacterized protein
Search

tr|T1EPU4|T1EPU4_HELRO
Uncharacterized protein
Search

tr|T1EPU5|T1EPU5_HELRO
Uncharacterized protein
Search

tr|T1EPU6|T1EPU6_HELRO
Uncharacterized protein
Search

tr|T1EPU7|T1EPU7_HELRO
Uncharacterized protein
Search

0.49	GO:0040008	regulation of growth
0.47	GO:0016567	protein ubiquitination
0.46	GO:0016310	phosphorylation

0.47	GO:0016301	kinase activity
0.46	GO:0005509	calcium ion binding
0.46	GO:0046983	protein dimerization activity
0.45	GO:0000976	transcription regulatory region sequence-specific DNA binding

tr|T1EPU8|T1EPU8_HELRO
Uncharacterized protein
Search

tr|T1EPU9|T1EPU9_HELRO
Uncharacterized protein
Search

tr|T1EPV0|T1EPV0_HELRO
Uncharacterized protein
Search

tr|T1EPV1|T1EPV1_HELRO
Uncharacterized protein
Search

tr|T1EPV2|T1EPV2_HELRO
Uncharacterized protein
Search

tr|T1EPV3|T1EPV3_HELRO
Uncharacterized protein
Search

tr|T1EPV4|T1EPV4_HELRO
Uncharacterized protein
Search

0.55	GO:0000723	telomere maintenance
0.51	GO:0032392	DNA geometric change
0.48	GO:0006310	DNA recombination
0.48	GO:0006281	DNA repair

0.63	GO:0004386	helicase activity
0.52	GO:0030554	adenyl nucleotide binding
0.51	GO:0097367	carbohydrate derivative binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0003676	nucleic acid binding
0.47	GO:0140097	catalytic activity, acting on DNA

tr|T1EPV5|T1EPV5_HELRO
Uncharacterized protein
Search

tr|T1EPV6|T1EPV6_HELRO
Uncharacterized protein
Search

tr|T1EPV7|T1EPV7_HELRO
Uncharacterized protein
Search

tr|T1EPV8|T1EPV8_HELRO
Uncharacterized protein
Search

tr|T1EPV9|T1EPV9_HELRO
Uncharacterized protein
Search

tr|T1EPW0|T1EPW0_HELRO
Uncharacterized protein
Search

tr|T1EPW1|T1EPW1_HELRO
Uncharacterized protein
Search

tr|T1EPW2|T1EPW2_HELRO
Uncharacterized protein
Search

tr|T1EPW3|T1EPW3_HELRO
Uncharacterized protein
Search

0.48	GO:0016310	phosphorylation
0.45	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic

0.55	GO:0046983	protein dimerization activity
0.50	GO:0016301	kinase activity
0.46	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.38	GO:0003676	nucleic acid binding

0.46

EC:3.1.26.4

GO:0004523

tr|T1EPW4|T1EPW4_HELRO
Uncharacterized protein
Search

tr|T1EPW5|T1EPW5_HELRO
Uncharacterized protein
Search

tr|T1EPW6|T1EPW6_HELRO
Uncharacterized protein
Search

tr|T1EPW7|T1EPW7_HELRO
Uncharacterized protein
Search

tr|T1EPW8|T1EPW8_HELRO
Uncharacterized protein
Search

tr|T1EPW9|T1EPW9_HELRO
Uncharacterized protein
Search

tr|T1EPX0|T1EPX0_HELRO
Uncharacterized protein
Search

tr|T1EPX1|T1EPX1_HELRO
Uncharacterized protein
Search

tr|T1EPX2|T1EPX2_HELRO
Uncharacterized protein
Search

tr|T1EPX3|T1EPX3_HELRO
Uncharacterized protein
Search

tr|T1EPX4|T1EPX4_HELRO
Uncharacterized protein
Search

tr|T1EPX5|T1EPX5_HELRO
Uncharacterized protein
Search

tr|T1EPX6|T1EPX6_HELRO
Uncharacterized protein
Search

tr|T1EPX7|T1EPX7_HELRO
Uncharacterized protein
Search

tr|T1EPX8|T1EPX8_HELRO
Uncharacterized protein
Search

tr|T1EPX9|T1EPX9_HELRO
Uncharacterized protein
Search

tr|T1EPY0|T1EPY0_HELRO
Uncharacterized protein
Search

tr|T1EPY1|T1EPY1_HELRO
Uncharacterized protein
Search

tr|T1EPY2|T1EPY2_HELRO
Uncharacterized protein
Search

tr|T1EPY3|T1EPY3_HELRO
Uncharacterized protein
Search

tr|T1EPY4|T1EPY4_HELRO
Uncharacterized protein
Search

tr|T1EPY5|T1EPY5_HELRO
Uncharacterized protein
Search

tr|T1EPY6|T1EPY6_HELRO
Uncharacterized protein
Search

tr|T1EPY7|T1EPY7_HELRO
Uncharacterized protein
Search

tr|T1EPY8|T1EPY8_HELRO
Uncharacterized protein
Search

tr|T1EPY9|T1EPY9_HELRO
Uncharacterized protein
Search

tr|T1EPZ0|T1EPZ0_HELRO
Uncharacterized protein
Search

tr|T1EPZ1|T1EPZ1_HELRO
Uncharacterized protein
Search

tr|T1EPZ2|T1EPZ2_HELRO
Uncharacterized protein
Search

tr|T1EPZ3|T1EPZ3_HELRO
Uncharacterized protein
Search

tr|T1EPZ4|T1EPZ4_HELRO
Uncharacterized protein
Search

tr|T1EPZ5|T1EPZ5_HELRO
Uncharacterized protein
Search

tr|T1EPZ6|T1EPZ6_HELRO
Uncharacterized protein
Search

0.50	GO:0043087	regulation of GTPase activity
0.45	GO:0007165	signal transduction
0.42	GO:0034622	cellular macromolecular complex assembly
0.40	GO:0036211	protein modification process
0.39	GO:0071824	protein-DNA complex subunit organization
0.39	GO:0030953	astral microtubule organization
0.39	GO:0006357	regulation of transcription by RNA polymerase II
0.39	GO:0044267	cellular protein metabolic process
0.38	GO:0007377	germ-band extension
0.38	GO:0016310	phosphorylation

0.46	GO:0046982	protein heterodimerization activity
0.40	GO:0035091	phosphatidylinositol binding
0.40	GO:0019787	ubiquitin-like protein transferase activity
0.40	GO:0004674	protein serine/threonine kinase activity
0.40	GO:0140110	transcription regulator activity
0.39	GO:0003676	nucleic acid binding
0.39	GO:0030276	clathrin binding
0.39	GO:0001095	TFIIE-class transcription factor binding
0.38	GO:0001097	TFIIH-class transcription factor binding
0.38	GO:0030554	adenyl nucleotide binding

0.43	GO:0005581	collagen trimer
0.43	GO:0005634	nucleus
0.40	GO:0031592	centrosomal corona
0.39	GO:0030136	clathrin-coated vesicle
0.38	GO:0070013	intracellular organelle lumen
0.37	GO:1990234	transferase complex
0.36	GO:0000793	condensed chromosome
0.36	GO:0005667	transcription factor complex
0.35	GO:0044427	chromosomal part
0.34	GO:0030529	intracellular ribonucleoprotein complex

0.40	EC:2.7.11	GO:0004674
0.37	KEGG:R00847	GO:0004370

tr|T1EPZ7|T1EPZ7_HELRO
Uncharacterized protein
Search

tr|T1EPZ8|T1EPZ8_HELRO
Uncharacterized protein
Search

0.39	GO:0006508	proteolysis
0.38	GO:1903506	regulation of nucleic acid-templated transcription
0.38	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.38	GO:0010468	regulation of gene expression
0.37	GO:0006836	neurotransmitter transport
0.36	GO:0008285	negative regulation of cell proliferation
0.36	GO:0006741	NADP biosynthetic process
0.35	GO:0005975	carbohydrate metabolic process
0.35	GO:0006351	transcription, DNA-templated
0.35	GO:0019674	NAD metabolic process

0.41	GO:0070001	aspartic-type peptidase activity
0.40	GO:0004175	endopeptidase activity
0.38	GO:0003677	DNA binding
0.37	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.37	GO:0005328	neurotransmitter:sodium symporter activity
0.37	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.37	GO:0008270	zinc ion binding
0.36	GO:0004888	transmembrane signaling receptor activity
0.35	GO:0030246	carbohydrate binding
0.35	GO:0003951	NAD+ kinase activity

0.38	GO:0005634	nucleus
0.37	GO:0005576	extracellular region
0.35	GO:0005887	integral component of plasma membrane

0.37	EC:2.7.7.6	GO:0003899
0.35	KEGG:R00104	GO:0003951

tr|T1EPZ9|T1EPZ9_HELRO
Uncharacterized protein
Search

0.57	Splicing regulatory glutamine/lysine-rich protein 1

0.46	GO:0001178	regulation of transcriptional start site selection at RNA polymerase II promoter
0.46	GO:0031440	regulation of mRNA 3'-end processing
0.45	GO:0006396	RNA processing
0.45	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.45	GO:0016071	mRNA metabolic process
0.38	GO:0022618	ribonucleoprotein complex assembly
0.35	GO:0007018	microtubule-based movement
0.35	GO:0016310	phosphorylation
0.34	GO:0007219	Notch signaling pathway
0.33	GO:0051726	regulation of cell cycle

0.55	GO:0003723	RNA binding
0.35	GO:0016301	kinase activity
0.35	GO:0003777	microtubule motor activity
0.33	GO:0004252	serine-type endopeptidase activity
0.33	GO:0031176	endo-1,4-beta-xylanase activity
0.33	GO:0003682	chromatin binding
0.33	GO:0016758	transferase activity, transferring hexosyl groups
0.33	GO:0004540	ribonuclease activity
0.32	GO:0022857	transmembrane transporter activity
0.32	GO:0046872	metal ion binding

0.41	GO:0005634	nucleus
0.38	GO:0120114	Sm-like protein family complex
0.36	GO:0030529	intracellular ribonucleoprotein complex
0.36	GO:0044446	intracellular organelle part
0.35	GO:1902494	catalytic complex
0.34	GO:0005856	cytoskeleton
0.34	GO:0005615	extracellular space
0.33	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.33

GO:0004252

tr|T1EQ00|T1EQ00_HELRO
Uncharacterized protein
Search

0.75	GO:0035335	peptidyl-tyrosine dephosphorylation
0.37	GO:0007377	germ-band extension
0.37	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling
0.37	GO:0007176	regulation of epidermal growth factor-activated receptor activity
0.37	GO:0046627	negative regulation of insulin receptor signaling pathway
0.37	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation
0.37	GO:0008285	negative regulation of cell proliferation
0.37	GO:0046426	negative regulation of JAK-STAT cascade
0.37	GO:0071456	cellular response to hypoxia
0.36	GO:0046580	negative regulation of Ras protein signal transduction

0.75	GO:0004725	protein tyrosine phosphatase activity
0.58	GO:0019198	transmembrane receptor protein phosphatase activity
0.36	GO:0005515	protein binding
0.34	GO:0005509	calcium ion binding
0.34	GO:0005201	extracellular matrix structural constituent
0.34	GO:0004896	cytokine receptor activity
0.33	GO:0003712	transcription cofactor activity
0.33	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0003723	RNA binding

0.44	GO:0005902	microvillus
0.38	GO:0005856	cytoskeleton
0.36	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0031253	cell projection membrane
0.36	GO:0016324	apical plasma membrane
0.34	GO:0005634	nucleus
0.34	GO:0044429	mitochondrial part
0.34	GO:0031967	organelle envelope
0.34	GO:0005578	proteinaceous extracellular matrix
0.33	GO:0005887	integral component of plasma membrane

0.75

EC:3.1.3.48

GO:0004725

tr|T1EQ01|T1EQ01_HELRO
Uncharacterized protein
Search

0.42

GO:0035556

intracellular signal transduction

0.48

GO:0046872

metal ion binding

0.36	GO:0005622	intracellular
0.30	GO:0044425	membrane part

tr|T1EQ02|T1EQ02_HELRO
Uncharacterized protein
Search

tr|T1EQ03|T1EQ03_HELRO
Uncharacterized protein
Search

tr|T1EQ04|T1EQ04_HELRO
Uncharacterized protein
Search

tr|T1EQ05|T1EQ05_HELRO
Uncharacterized protein
Search

tr|T1EQ06|T1EQ06_HELRO
Uncharacterized protein
Search

tr|T1EQ07|T1EQ07_HELRO
Uncharacterized protein
Search

0.47	GO:0060963	positive regulation of ribosomal protein gene transcription by RNA polymerase II
0.45	GO:0008361	regulation of cell size
0.45	GO:0051726	regulation of cell cycle
0.44	GO:1901717	positive regulation of gamma-aminobutyric acid catabolic process
0.44	GO:1901714	positive regulation of urea catabolic process
0.43	GO:0001080	nitrogen catabolite activation of transcription from RNA polymerase II promoter
0.43	GO:0065004	protein-DNA complex assembly
0.43	GO:0051321	meiotic cell cycle
0.43	GO:0098653	centromere clustering
0.42	GO:0007059	chromosome segregation

0.43	GO:0001128	RNA polymerase II transcription coactivator activity involved in preinitiation complex assembly
0.42	GO:0003676	nucleic acid binding
0.42	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting
0.42	GO:0009982	pseudouridine synthase activity
0.41	GO:0035299	inositol pentakisphosphate 2-kinase activity
0.41	GO:0005509	calcium ion binding
0.40	GO:0016307	phosphatidylinositol phosphate kinase activity
0.40	GO:0019901	protein kinase binding
0.40	GO:0005044	scavenger receptor activity
0.40	GO:0030554	adenyl nucleotide binding

0.46	GO:0005634	nucleus
0.41	GO:0005856	cytoskeleton
0.41	GO:0005700	polytene chromosome
0.40	GO:0070013	intracellular organelle lumen
0.40	GO:0000777	condensed chromosome kinetochore
0.39	GO:0005764	lysosome
0.38	GO:0005615	extracellular space
0.35	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.42	EC:5.4.99.12	GO:0009982
0.41	KEGG:R05202	GO:0035299

tr|T1EQ08|T1EQ08_HELRO
Uncharacterized protein
Search

tr|T1EQ09|T1EQ09_HELRO
Uncharacterized protein
Search

tr|T1EQ10|T1EQ10_HELRO
Uncharacterized protein
Search

tr|T1EQ11|T1EQ11_HELRO
Uncharacterized protein
Search

tr|T1EQ12|T1EQ12_HELRO
Uncharacterized protein
Search

tr|T1EQ13|T1EQ13_HELRO
Uncharacterized protein
Search

tr|T1EQ14|T1EQ14_HELRO
Uncharacterized protein
Search

0.69	GO:0046907	intracellular transport
0.42	GO:0046604	positive regulation of mitotic centrosome separation
0.41	GO:0000082	G1/S transition of mitotic cell cycle
0.40	GO:0006606	protein import into nucleus
0.40	GO:0007051	spindle organization
0.39	GO:0043547	positive regulation of GTPase activity
0.39	GO:0006405	RNA export from nucleus
0.39	GO:0006511	ubiquitin-dependent protein catabolic process

0.50	GO:0046872	metal ion binding
0.40	GO:0008536	Ran GTPase binding
0.39	GO:0005096	GTPase activator activity
0.39	GO:0016874	ligase activity

0.45	GO:0005622	intracellular
0.36	GO:0043228	non-membrane-bounded organelle
0.36	GO:0044422	organelle part
0.35	GO:0043227	membrane-bounded organelle

0.39

EC:6

GO:0016874

tr|T1EQ15|T1EQ15_HELRO
Uncharacterized protein
Search

tr|T1EQ16|T1EQ16_HELRO
Uncharacterized protein
Search

tr|T1EQ17|T1EQ17_HELRO
Uncharacterized protein
Search

tr|T1EQ18|T1EQ18_HELRO
Uncharacterized protein
Search

tr|T1EQ19|T1EQ19_HELRO
Uncharacterized protein
Search

tr|T1EQ20|T1EQ20_HELRO
Uncharacterized protein
Search

0.77

GO:0035725

sodium ion transmembrane transport

0.81

GO:0005272

sodium channel activity

0.30

GO:0031224

intrinsic component of membrane

tr|T1EQ21|T1EQ21_HELRO
Uncharacterized protein
Search

0.77	GO:0035725	sodium ion transmembrane transport
0.35	GO:0007165	signal transduction

0.81	GO:0005272	sodium channel activity
0.38	GO:0005230	extracellular ligand-gated ion channel activity
0.37	GO:0099600	transmembrane receptor activity
0.36	GO:0038023	signaling receptor activity

0.30

GO:0031224

intrinsic component of membrane

tr|T1EQ22|T1EQ22_HELRO
Uncharacterized protein
Search

0.49	GO:0051568	histone H3-K4 methylation
0.41	GO:0006261	DNA-dependent DNA replication
0.40	GO:0006413	translational initiation
0.40	GO:0006355	regulation of transcription, DNA-templated
0.40	GO:0071897	DNA biosynthetic process
0.38	GO:0006468	protein phosphorylation
0.37	GO:0006508	proteolysis
0.37	GO:0006364	rRNA processing

0.49	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.44	GO:0050825	ice binding
0.41	GO:0046872	metal ion binding
0.41	GO:0003887	DNA-directed DNA polymerase activity
0.41	GO:0003743	translation initiation factor activity
0.39	GO:0003700	DNA binding transcription factor activity
0.38	GO:0004672	protein kinase activity
0.38	GO:0008374	O-acyltransferase activity
0.37	GO:0008233	peptidase activity
0.36	GO:0030554	adenyl nucleotide binding

0.47	GO:0035097	histone methyltransferase complex
0.39	GO:0032040	small-subunit processome
0.30	GO:0016020	membrane

0.41

EC:2.7.7.7

GO:0003887

tr|T1EQ23|T1EQ23_HELRO
Uncharacterized protein
Search

tr|T1EQ24|T1EQ24_HELRO
Uncharacterized protein
Search

tr|T1EQ25|T1EQ25_HELRO
Uncharacterized protein
Search

0.11	Homeobox protein Meis1 (Fragment)

0.55	GO:2001141	regulation of RNA biosynthetic process
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.45	GO:0035855	megakaryocyte development
0.45	GO:0002089	lens morphogenesis in camera-type eye
0.45	GO:0060216	definitive hemopoiesis
0.45	GO:0045638	negative regulation of myeloid cell differentiation
0.44	GO:0045665	negative regulation of neuron differentiation
0.43	GO:0007626	locomotory behavior
0.43	GO:0048646	anatomical structure formation involved in morphogenesis

0.55	GO:0003677	DNA binding
0.44	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.44	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.42	GO:0003682	chromatin binding
0.42	GO:0001067	regulatory region nucleic acid binding
0.42	GO:0046982	protein heterodimerization activity

0.60	GO:0005634	nucleus
0.43	GO:0005667	transcription factor complex
0.36	GO:0031974	membrane-enclosed lumen
0.34	GO:0044446	intracellular organelle part
0.33	GO:0005737	cytoplasm

tr|T1EQ26|T1EQ26_HELRO
Uncharacterized protein
Search

tr|T1EQ27|T1EQ27_HELRO
Uncharacterized protein
Search

tr|T1EQ28|T1EQ28_HELRO
Uncharacterized protein
Search

tr|T1EQ29|T1EQ29_HELRO
Uncharacterized protein
Search

tr|T1EQ30|T1EQ30_HELRO
Uncharacterized protein
Search

tr|T1EQ31|T1EQ31_HELRO
Uncharacterized protein
Search

tr|T1EQ32|T1EQ32_HELRO
Uncharacterized protein
Search

tr|T1EQ33|T1EQ33_HELRO
Uncharacterized protein
Search

tr|T1EQ34|T1EQ34_HELRO
Uncharacterized protein
Search

tr|T1EQ35|T1EQ35_HELRO
Uncharacterized protein
Search

tr|T1EQ36|T1EQ36_HELRO
Uncharacterized protein
Search

tr|T1EQ37|T1EQ37_HELRO
Uncharacterized protein
Search

tr|T1EQ38|T1EQ38_HELRO
Uncharacterized protein
Search

tr|T1EQ39|T1EQ39_HELRO
Uncharacterized protein
Search

tr|T1EQ40|T1EQ40_HELRO
Uncharacterized protein
Search

tr|T1EQ41|T1EQ41_HELRO
Uncharacterized protein
Search

COA7

0.62	cytochrome c oxidase assembly factor 7

0.45	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.44	GO:0006289	nucleotide-excision repair
0.37	GO:0009116	nucleoside metabolic process

0.43	GO:0003684	damaged DNA binding
0.37	GO:0070003	threonine-type peptidase activity
0.36	GO:0017061	S-methyl-5-thioadenosine phosphorylase activity
0.35	GO:0004175	endopeptidase activity

0.58	GO:0005634	nucleus
0.58	GO:0005739	mitochondrion
0.51	GO:0031970	organelle envelope lumen
0.38	GO:0019773	proteasome core complex, alpha-subunit complex
0.30	GO:0031224	intrinsic component of membrane

0.36

EC:2.4.2.28

GO:0017061

tr|T1EQ43|T1EQ43_HELRO
Uncharacterized protein
Search

tr|T1EQ44|T1EQ44_HELRO
Uncharacterized protein
Search

tr|T1EQ45|T1EQ45_HELRO
Uncharacterized protein
Search

tr|T1EQ46|T1EQ46_HELRO
Uncharacterized protein
Search

0.76	GO:0030010	establishment of cell polarity
0.71	GO:0000226	microtubule cytoskeleton organization
0.63	GO:0006468	protein phosphorylation
0.35	GO:0018209	peptidyl-serine modification
0.35	GO:0035556	intracellular signal transduction
0.35	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity
0.34	GO:0010976	positive regulation of neuron projection development
0.34	GO:0050770	regulation of axonogenesis
0.34	GO:0043066	negative regulation of apoptotic process
0.33	GO:0018210	peptidyl-threonine modification

0.67	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0005509	calcium ion binding
0.35	GO:0010857	calcium-dependent protein kinase activity
0.34	GO:0045296	cadherin binding
0.34	GO:0005516	calmodulin binding
0.33	GO:0008107	galactoside 2-alpha-L-fucosyltransferase activity
0.33	GO:0000287	magnesium ion binding

0.35	GO:0097427	microtubule bundle
0.35	GO:0016328	lateral plasma membrane
0.34	GO:0005884	actin filament
0.34	GO:0005634	nucleus
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0030131	clathrin adaptor complex
0.30	GO:0016021	integral component of membrane

0.67

GO:0004674

tr|T1EQ47|T1EQ47_HELRO
Uncharacterized protein
Search

MARK2

0.65	Serine/threonine-protein kinase MARK2 (Fragment)

0.82	GO:0030010	establishment of cell polarity
0.76	GO:0000226	microtubule cytoskeleton organization
0.63	GO:0006468	protein phosphorylation
0.50	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity
0.49	GO:0010976	positive regulation of neuron projection development
0.49	GO:0050770	regulation of axonogenesis
0.42	GO:0035556	intracellular signal transduction
0.37	GO:0001764	neuron migration
0.36	GO:0016055	Wnt signaling pathway
0.36	GO:0051493	regulation of cytoskeleton organization

0.70	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0045296	cadherin binding
0.42	GO:0000287	magnesium ion binding
0.38	GO:0050321	tau-protein kinase activity
0.35	GO:0008289	lipid binding
0.34	GO:0030295	protein kinase activator activity
0.33	GO:0003723	RNA binding

0.52	GO:0097427	microtubule bundle
0.50	GO:0016328	lateral plasma membrane
0.49	GO:0005884	actin filament
0.44	GO:0005654	nucleoplasm
0.36	GO:0045180	basal cortex
0.33	GO:0005739	mitochondrion

0.70

GO:0004674

tr|T1EQ48|T1EQ48_HELRO
Uncharacterized protein
Search

0.61	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.58	GO:0016266	O-glycan processing
0.56	GO:0048015	phosphatidylinositol-mediated signaling
0.47	GO:0005975	carbohydrate metabolic process

0.56	GO:0005201	extracellular matrix structural constituent
0.50	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.44	GO:0003723	RNA binding

0.60	GO:0005796	Golgi lumen
0.59	GO:0070701	mucus layer
0.56	GO:0070062	extracellular exosome
0.45	GO:0005634	nucleus
0.43	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.50

EC:3.2.1

GO:0004553

tr|T1EQ49|T1EQ49_HELRO
Uncharacterized protein
Search

tr|T1EQ50|T1EQ50_HELRO
Uncharacterized protein
Search

tr|T1EQ51|T1EQ51_HELRO
Uncharacterized protein
Search

tr|T1EQ52|T1EQ52_HELRO
Uncharacterized protein
Search

0.46	GO:0007165	signal transduction
0.41	GO:0034220	ion transmembrane transport
0.40	GO:0006468	protein phosphorylation

0.46	GO:0005230	extracellular ligand-gated ion channel activity
0.44	GO:0099600	transmembrane receptor activity
0.42	GO:0038023	signaling receptor activity
0.40	GO:0004672	protein kinase activity
0.40	GO:0046872	metal ion binding
0.37	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0044425

membrane part

tr|T1EQ53|T1EQ53_HELRO
Uncharacterized protein
Search

0.38	GO:0090304	nucleic acid metabolic process
0.38	GO:0031505	fungal-type cell wall organization
0.37	GO:0071450	cellular response to oxygen radical
0.37	GO:0000303	response to superoxide
0.37	GO:0006801	superoxide metabolic process
0.37	GO:0071805	potassium ion transmembrane transport
0.37	GO:0005975	carbohydrate metabolic process
0.37	GO:0006629	lipid metabolic process
0.36	GO:0045892	negative regulation of transcription, DNA-templated
0.36	GO:0098869	cellular oxidant detoxification

0.40	GO:0035438	cyclic-di-GMP binding
0.40	GO:0008889	glycerophosphodiester phosphodiesterase activity
0.39	GO:0016740	transferase activity
0.38	GO:0008061	chitin binding
0.38	GO:0005249	voltage-gated potassium channel activity
0.38	GO:0004784	superoxide dismutase activity
0.38	GO:0004518	nuclease activity
0.37	GO:0001882	nucleoside binding
0.37	GO:0003676	nucleic acid binding
0.37	GO:0140098	catalytic activity, acting on RNA

0.38	GO:0008076	voltage-gated potassium channel complex
0.33	GO:0005622	intracellular

0.40

EC:3.1.4.46

GO:0008889

tr|T1EQ54|T1EQ54_HELRO
Uncharacterized protein
Search

tr|T1EQ55|T1EQ55_HELRO
Uncharacterized protein
Search

tr|T1EQ56|T1EQ56_HELRO
Uncharacterized protein
Search

tr|T1EQ57|T1EQ57_HELRO
Uncharacterized protein
Search

tr|T1EQ58|T1EQ58_HELRO
Uncharacterized protein
Search

tr|T1EQ59|T1EQ59_HELRO
Uncharacterized protein
Search

0.44	GO:0071840	cellular component organization or biogenesis
0.43	GO:0006886	intracellular protein transport
0.43	GO:0016192	vesicle-mediated transport
0.42	GO:0016072	rRNA metabolic process
0.41	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.41	GO:0034470	ncRNA processing
0.40	GO:0048666	neuron development
0.39	GO:0036211	protein modification process
0.38	GO:0009653	anatomical structure morphogenesis
0.38	GO:0044267	cellular protein metabolic process

0.49	GO:0005509	calcium ion binding
0.41	GO:0004521	endoribonuclease activity
0.39	GO:0003712	transcription cofactor activity
0.38	GO:0017076	purine nucleotide binding
0.38	GO:0097367	carbohydrate derivative binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0005515	protein binding
0.37	GO:0008144	drug binding
0.37	GO:0140096	catalytic activity, acting on a protein
0.37	GO:0016772	transferase activity, transferring phosphorus-containing groups

0.44	GO:0030117	membrane coat
0.41	GO:0031012	extracellular matrix
0.40	GO:0005634	nucleus
0.39	GO:0030684	preribosome
0.38	GO:0070013	intracellular organelle lumen
0.37	GO:1990234	transferase complex
0.36	GO:0044446	intracellular organelle part
0.36	GO:1905368	peptidase complex
0.36	GO:0005732	small nucleolar ribonucleoprotein complex
0.35	GO:0043232	intracellular non-membrane-bounded organelle

0.37

EC:2.7

GO:0016772

tr|T1EQ60|T1EQ60_HELRO
Uncharacterized protein
Search

0.58	GO:0034968	histone lysine methylation
0.39	GO:0043044	ATP-dependent chromatin remodeling
0.38	GO:0045944	positive regulation of transcription by RNA polymerase II
0.38	GO:0051809	passive evasion of immune response of other organism involved in symbiotic interaction
0.38	GO:0007399	nervous system development
0.38	GO:0018023	peptidyl-lysine trimethylation
0.36	GO:0020012	evasion or tolerance of host immune response

0.58	GO:0018024	histone-lysine N-methyltransferase activity
0.42	GO:0046872	metal ion binding
0.38	GO:0008134	transcription factor binding
0.37	GO:0003677	DNA binding
0.37	GO:0003682	chromatin binding

0.50	GO:0005634	nucleus
0.40	GO:0005700	polytene chromosome
0.39	GO:0031974	membrane-enclosed lumen
0.38	GO:0000785	chromatin
0.37	GO:1904949	ATPase complex
0.30	GO:0016020	membrane

0.58

EC:2.1.1.43

GO:0018024

tr|T1EQ61|T1EQ61_HELRO
Uncharacterized protein
Search

tr|T1EQ62|T1EQ62_HELRO
Uncharacterized protein
Search

tr|T1EQ63|T1EQ63_HELRO
Uncharacterized protein
Search

tr|T1EQ64|T1EQ64_HELRO
Uncharacterized protein
Search

tr|T1EQ65|T1EQ65_HELRO
Uncharacterized protein
Search

tr|T1EQ66|T1EQ66_HELRO
Uncharacterized protein
Search

tr|T1EQ67|T1EQ67_HELRO
Uncharacterized protein
Search

tr|T1EQ68|T1EQ68_HELRO
Uncharacterized protein
Search

tr|T1EQ69|T1EQ69_HELRO
Uncharacterized protein
Search

tr|T1EQ70|T1EQ70_HELRO
Uncharacterized protein
Search

0.51	GO:0007165	signal transduction
0.50	GO:0044806	G-quadruplex DNA unwinding
0.50	GO:0032211	negative regulation of telomere maintenance via telomerase
0.50	GO:0051974	negative regulation of telomerase activity
0.48	GO:0000002	mitochondrial genome maintenance
0.44	GO:0032508	DNA duplex unwinding
0.43	GO:0036065	fucosylation
0.42	GO:0006260	DNA replication
0.42	GO:0006486	protein glycosylation
0.38	GO:0005975	carbohydrate metabolic process

0.50	GO:0010521	telomerase inhibitor activity
0.48	GO:0046872	metal ion binding
0.47	GO:0043141	ATP-dependent 5'-3' DNA helicase activity
0.44	GO:0008107	galactoside 2-alpha-L-fucosyltransferase activity
0.41	GO:0004930	G-protein coupled receptor activity

0.45	GO:0005657	replication fork
0.43	GO:0032580	Golgi cisterna membrane
0.41	GO:0005634	nucleus
0.40	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

0.47

EC:3.6.1

GO:0043141

tr|T1EQ71|T1EQ71_HELRO
Uncharacterized protein
Search

0.56	GO:0006396	RNA processing
0.40	GO:0006464	cellular protein modification process
0.39	GO:0007018	microtubule-based movement
0.38	GO:0016310	phosphorylation
0.36	GO:0005975	carbohydrate metabolic process

0.41	GO:0004674	protein serine/threonine kinase activity
0.40	GO:0008061	chitin binding
0.39	GO:0003777	microtubule motor activity
0.39	GO:0004842	ubiquitin-protein transferase activity
0.37	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
0.37	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0016874	ligase activity
0.35	GO:0003677	DNA binding
0.35	GO:0046872	metal ion binding

0.37	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.41	EC:2.7.11	GO:0004674
0.39	KEGG:R03876	GO:0004842

tr|T1EQ72|T1EQ72_HELRO
Uncharacterized protein
Search

0.62	GO:0030100	regulation of endocytosis
0.41	GO:0048711	positive regulation of astrocyte differentiation
0.41	GO:0060988	lipid tube assembly
0.40	GO:0051647	nucleus localization
0.40	GO:0071156	regulation of cell cycle arrest
0.39	GO:0006997	nucleus organization
0.39	GO:0042692	muscle cell differentiation
0.39	GO:0045664	regulation of neuron differentiation
0.39	GO:0043065	positive regulation of apoptotic process
0.34	GO:0048488	synaptic vesicle endocytosis

0.43	GO:0005543	phospholipid binding
0.41	GO:0048156	tau protein binding
0.39	GO:0032403	protein complex binding
0.39	GO:0070063	RNA polymerase binding
0.38	GO:0042802	identical protein binding
0.38	GO:0003779	actin binding
0.34	GO:0008022	protein C-terminus binding
0.34	GO:0004252	serine-type endopeptidase activity
0.34	GO:0046982	protein heterodimerization activity

0.49	GO:0005737	cytoplasm
0.45	GO:0031256	leading edge membrane
0.42	GO:0060987	lipid tube
0.41	GO:0043005	neuron projection
0.39	GO:0012505	endomembrane system
0.37	GO:0098793	presynapse
0.37	GO:0044428	nuclear part
0.37	GO:0120038	plasma membrane bounded cell projection part
0.36	GO:0097708	intracellular vesicle
0.36	GO:0031967	organelle envelope

0.34

GO:0004252

tr|T1EQ73|T1EQ73_HELRO
Uncharacterized protein
Search

tr|T1EQ74|T1EQ74_HELRO
Uncharacterized protein
Search

GRPEL1

0.75	GrpE like 1, mitochondrial

0.69	GO:0006457	protein folding
0.69	GO:0050790	regulation of catalytic activity
0.44	GO:0030150	protein import into mitochondrial matrix
0.33	GO:0044093	positive regulation of molecular function
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0010467	gene expression

0.79	GO:0000774	adenyl-nucleotide exchange factor activity
0.77	GO:0051087	chaperone binding
0.75	GO:0042803	protein homodimerization activity
0.44	GO:0051082	unfolded protein binding
0.34	GO:0051117	ATPase binding
0.34	GO:0001671	ATPase activator activity
0.33	GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors
0.33	GO:0043565	sequence-specific DNA binding
0.33	GO:0003735	structural constituent of ribosome
0.32	GO:0016787	hydrolase activity

0.71	GO:0005759	mitochondrial matrix
0.46	GO:0001405	presequence translocase-associated import motor
0.39	GO:0005634	nucleus
0.33	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.33

EC:1.7

GO:0016661

tr|T1EQ75|T1EQ75_HELRO
Uncharacterized protein
Search

tr|T1EQ76|T1EQ76_HELRO
Uncharacterized protein
Search

tr|T1EQ77|T1EQ77_HELRO
Uncharacterized protein
Search

0.42	GO:0045773	positive regulation of axon extension
0.42	GO:0090109	regulation of cell-substrate junction assembly
0.42	GO:1903391	regulation of adherens junction organization
0.42	GO:0043001	Golgi to plasma membrane protein transport
0.42	GO:0001952	regulation of cell-matrix adhesion
0.41	GO:0032886	regulation of microtubule-based process
0.41	GO:0030334	regulation of cell migration
0.35	GO:0009611	response to wounding
0.35	GO:0060832	oocyte animal/vegetal axis specification
0.34	GO:0008090	retrograde axonal transport

0.74	GO:0008017	microtubule binding
0.69	GO:0005509	calcium ion binding
0.60	GO:0003779	actin binding
0.44	GO:0002162	dystroglycan binding
0.41	GO:0050839	cell adhesion molecule binding
0.40	GO:0032403	protein complex binding
0.34	GO:0008022	protein C-terminus binding
0.34	GO:0008093	cytoskeletal adaptor activity
0.33	GO:0042803	protein homodimerization activity
0.33	GO:0005102	receptor binding

0.60	GO:0005856	cytoskeleton
0.42	GO:0032587	ruffle membrane
0.40	GO:0099512	supramolecular fiber
0.39	GO:0005794	Golgi apparatus
0.36	GO:0044446	intracellular organelle part
0.35	GO:0030056	hemidesmosome
0.34	GO:0014704	intercalated disc
0.34	GO:1904115	axon cytoplasm
0.34	GO:0042383	sarcolemma
0.34	GO:0014069	postsynaptic density

0.33

EC:3.6.1.3

GO:0016887

tr|T1EQ78|T1EQ78_HELRO
Uncharacterized protein
Search

tr|T1EQ79|T1EQ79_HELRO
Uncharacterized protein
Search

tr|T1EQ80|T1EQ80_HELRO
Phospholipid scramblase
Search

0.49	Phospholipid scramblase

tr|T1EQ81|T1EQ81_HELRO
Uncharacterized protein
Search

tr|T1EQ82|T1EQ82_HELRO
Uncharacterized protein
Search

tr|T1EQ83|T1EQ83_HELRO
Uncharacterized protein
Search

tr|T1EQ84|T1EQ84_HELRO
Uncharacterized protein
Search

tr|T1EQ85|T1EQ85_HELRO
Uncharacterized protein
Search

tr|T1EQ86|T1EQ86_HELRO
Uncharacterized protein
Search

tr|T1EQ87|T1EQ87_HELRO
Uncharacterized protein
Search

tr|T1EQ88|T1EQ88_HELRO
Uncharacterized protein
Search

tr|T1EQ89|T1EQ89_HELRO
Uncharacterized protein
Search

tr|T1EQ90|T1EQ90_HELRO
Uncharacterized protein
Search

tr|T1EQ91|T1EQ91_HELRO
Uncharacterized protein
Search

tr|T1EQ92|T1EQ92_HELRO
Uncharacterized protein
Search

0.45	GO:0048675	axon extension
0.44	GO:0060026	convergent extension
0.44	GO:0000412	histone peptidyl-prolyl isomerization
0.44	GO:0008593	regulation of Notch signaling pathway
0.43	GO:0001944	vasculature development
0.43	GO:0045664	regulation of neuron differentiation
0.42	GO:0007417	central nervous system development
0.41	GO:0016567	protein ubiquitination
0.41	GO:0016070	RNA metabolic process
0.41	GO:0031323	regulation of cellular metabolic process

0.46	GO:0005509	calcium ion binding
0.45	GO:0003696	satellite DNA binding
0.44	GO:0005528	FK506 binding
0.44	GO:0008201	heparin binding
0.43	GO:0140096	catalytic activity, acting on a protein
0.42	GO:0003682	chromatin binding
0.41	GO:0016859	cis-trans isomerase activity
0.40	GO:0046914	transition metal ion binding
0.39	GO:0005515	protein binding
0.39	GO:0003899	DNA-directed 5'-3' RNA polymerase activity

0.48	GO:0005634	nucleus
0.43	GO:0070013	intracellular organelle lumen
0.42	GO:0000775	chromosome, centromeric region
0.40	GO:0000792	heterochromatin
0.39	GO:0000793	condensed chromosome
0.38	GO:0032040	small-subunit processome
0.36	GO:0019005	SCF ubiquitin ligase complex
0.35	GO:0005874	microtubule
0.35	GO:0005576	extracellular region
0.34	GO:0005829	cytosol

0.41

EC:5.2

GO:0016859

tr|T1EQ93|T1EQ93_HELRO
Uncharacterized protein
Search

tr|T1EQ94|T1EQ94_HELRO
Uncharacterized protein
Search

0.61	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4

0.68	GO:0071805	potassium ion transmembrane transport
0.62	GO:0043269	regulation of ion transport
0.62	GO:0034762	regulation of transmembrane transport
0.52	GO:0016057	regulation of membrane potential in photoreceptor cell
0.52	GO:0007637	proboscis extension reflex
0.52	GO:0071632	optomotor response
0.52	GO:0050802	circadian sleep/wake cycle, sleep
0.51	GO:0071484	cellular response to light intensity
0.51	GO:0045938	positive regulation of circadian sleep/wake cycle, sleep
0.50	GO:0050433	regulation of catecholamine secretion

0.72	GO:0005249	voltage-gated potassium channel activity
0.34	GO:0004692	cGMP-dependent protein kinase activity
0.32	GO:0003677	DNA binding

0.37	GO:0005887	integral component of plasma membrane
0.33	GO:0005634	nucleus

0.34

GO:0004692

tr|T1EQ95|T1EQ95_HELRO
Uncharacterized protein
Search

0.70	GO:0071805	potassium ion transmembrane transport
0.64	GO:0043269	regulation of ion transport
0.64	GO:0034762	regulation of transmembrane transport
0.62	GO:0002027	regulation of heart rate
0.56	GO:0006814	sodium ion transport
0.53	GO:0042391	regulation of membrane potential
0.51	GO:0071321	cellular response to cGMP
0.51	GO:0086018	SA node cell to atrial cardiac muscle cell signaling
0.50	GO:0071320	cellular response to cAMP
0.49	GO:0086004	regulation of cardiac muscle cell contraction

0.74	GO:0005249	voltage-gated potassium channel activity
0.62	GO:0030552	cAMP binding
0.51	GO:0005222	intracellular cAMP activated cation channel activity
0.51	GO:0005248	voltage-gated sodium channel activity
0.45	GO:0042802	identical protein binding
0.34	GO:0004692	cGMP-dependent protein kinase activity
0.32	GO:0003677	DNA binding

0.51	GO:0098855	HCN channel complex
0.46	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0030424	axon
0.34	GO:0043679	axon terminus
0.34	GO:0016323	basolateral plasma membrane
0.34	GO:0043025	neuronal cell body
0.33	GO:0005634	nucleus

0.34

GO:0004692

tr|T1EQ96|T1EQ96_HELRO
Uncharacterized protein
Search

0.55	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2

0.65	GO:0071805	potassium ion transmembrane transport
0.59	GO:0043269	regulation of ion transport
0.58	GO:0034762	regulation of transmembrane transport
0.52	GO:0016057	regulation of membrane potential in photoreceptor cell
0.52	GO:0007637	proboscis extension reflex
0.52	GO:0071632	optomotor response
0.52	GO:0050802	circadian sleep/wake cycle, sleep
0.51	GO:0071484	cellular response to light intensity
0.51	GO:0045938	positive regulation of circadian sleep/wake cycle, sleep
0.50	GO:0050433	regulation of catecholamine secretion

0.70	GO:0005216	ion channel activity
0.67	GO:0022832	voltage-gated channel activity
0.65	GO:0015079	potassium ion transmembrane transporter activity
0.32	GO:0003677	DNA binding

0.35	GO:0005887	integral component of plasma membrane
0.33	GO:0005634	nucleus

tr|T1EQ97|T1EQ97_HELRO
Uncharacterized protein
Search

0.57	GO:0071805	potassium ion transmembrane transport
0.49	GO:0034765	regulation of ion transmembrane transport
0.37	GO:0042391	regulation of membrane potential
0.33	GO:0006265	DNA topological change
0.33	GO:0006468	protein phosphorylation
0.32	GO:0006508	proteolysis

0.63	GO:0005216	ion channel activity
0.58	GO:0022832	voltage-gated channel activity
0.57	GO:0015079	potassium ion transmembrane transporter activity
0.34	GO:0004692	cGMP-dependent protein kinase activity
0.33	GO:0061505	DNA topoisomerase II activity
0.33	GO:0008094	DNA-dependent ATPase activity
0.33	GO:0004222	metalloendopeptidase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0003677	DNA binding
0.32	GO:0008144	drug binding

0.35

GO:0005887

integral component of plasma membrane

0.34

GO:0004692

tr|T1EQ98|T1EQ98_HELRO
Uncharacterized protein
Search

0.44	GO:0001522	pseudouridine synthesis
0.40	GO:0006357	regulation of transcription by RNA polymerase II
0.38	GO:0006468	protein phosphorylation
0.38	GO:0032502	developmental process
0.38	GO:0003053	circadian regulation of heart rate
0.38	GO:0006351	transcription, DNA-templated
0.37	GO:0048523	negative regulation of cellular process
0.37	GO:0007346	regulation of mitotic cell cycle
0.37	GO:0045187	regulation of circadian sleep/wake cycle, sleep
0.37	GO:0045893	positive regulation of transcription, DNA-templated

0.49	GO:0003676	nucleic acid binding
0.43	GO:0009982	pseudouridine synthase activity
0.39	GO:0003700	DNA binding transcription factor activity
0.38	GO:0016301	kinase activity
0.38	GO:0030554	adenyl nucleotide binding
0.38	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.38	GO:0004386	helicase activity
0.38	GO:0008270	zinc ion binding
0.38	GO:0003682	chromatin binding
0.37	GO:0097367	carbohydrate derivative binding

0.42	GO:0005634	nucleus
0.36	GO:0005700	polytene chromosome
0.36	GO:0008540	proteasome regulatory particle, base subcomplex
0.36	GO:0017053	transcriptional repressor complex
0.35	GO:0005667	transcription factor complex
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.43

EC:5.4.99.12

GO:0009982

tr|T1EQ99|T1EQ99_HELRO
Uncharacterized protein
Search

tr|T1EQA0|T1EQA0_HELRO
Uncharacterized protein
Search

0.46	GO:0032958	inositol phosphate biosynthetic process
0.45	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.44	GO:0051171	regulation of nitrogen compound metabolic process
0.44	GO:0080090	regulation of primary metabolic process
0.44	GO:0010468	regulation of gene expression
0.41	GO:0042254	ribosome biogenesis
0.39	GO:0016310	phosphorylation
0.37	GO:0071824	protein-DNA complex subunit organization
0.37	GO:0097466	ubiquitin-dependent glycoprotein ERAD pathway
0.37	GO:0048522	positive regulation of cellular process

0.46	GO:0003700	DNA binding transcription factor activity
0.40	GO:0016301	kinase activity
0.38	GO:0034511	U3 snoRNA binding
0.37	GO:0001129	RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly
0.37	GO:0097367	carbohydrate derivative binding
0.37	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
0.36	GO:0017178	diphthine-ammonia ligase activity
0.36	GO:0017025	TBP-class protein binding
0.36	GO:0043168	anion binding
0.36	GO:0017076	purine nucleotide binding

0.42	GO:0005634	nucleus
0.38	GO:1990234	transferase complex
0.37	GO:0030686	90S preribosome
0.37	GO:0045335	phagocytic vesicle
0.36	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex
0.36	GO:0044446	intracellular organelle part
0.35	GO:0005667	transcription factor complex
0.35	GO:0005783	endoplasmic reticulum
0.35	GO:0005739	mitochondrion
0.35	GO:0070013	intracellular organelle lumen

0.37	EC:3.2.1.113	GO:0004571
0.37	KEGG:R05982 KEGG:R06722	GO:0004571

tr|T1EQA1|T1EQA1_HELRO
Uncharacterized protein
Search

tr|T1EQA2|T1EQA2_HELRO
Uncharacterized protein
Search

tr|T1EQA3|T1EQA3_HELRO
Uncharacterized protein
Search

tr|T1EQA4|T1EQA4_HELRO
Uncharacterized protein
Search

tr|T1EQA5|T1EQA5_HELRO
Uncharacterized protein
Search

0.72	GO:0006465	signal peptide processing
0.60	GO:0016577	histone demethylation
0.56	GO:0051321	meiotic cell cycle
0.56	GO:0006338	chromatin remodeling

0.60	GO:0032452	histone demethylase activity
0.56	GO:0008233	peptidase activity

0.74	GO:0005787	signal peptidase complex
0.55	GO:0000790	nuclear chromatin
0.30	GO:0016021	integral component of membrane

0.56

EC:3.4

GO:0008233

tr|T1EQA6|T1EQA6_HELRO
Uncharacterized protein
Search

tr|T1EQA7|T1EQA7_HELRO
Uncharacterized protein
Search

tr|T1EQA8|T1EQA8_HELRO
Uncharacterized protein
Search

0.38

GO:0022008

neurogenesis

0.33	GO:0005840	ribosome
0.30	GO:0044425	membrane part

tr|T1EQA9|T1EQA9_HELRO
Uncharacterized protein
Search

tr|T1EQB0|T1EQB0_HELRO
Uncharacterized protein
Search

tr|T1EQB1|T1EQB1_HELRO
Uncharacterized protein
Search

tr|T1EQB2|T1EQB2_HELRO
Uncharacterized protein
Search

tr|T1EQB3|T1EQB3_HELRO
Uncharacterized protein
Search

0.64	Integrator complex subunit 2

0.83	GO:0016180	snRNA processing
0.43	GO:0043628	ncRNA 3'-end processing
0.34	GO:0042795	snRNA transcription by RNA polymerase II
0.33	GO:0006357	regulation of transcription by RNA polymerase II

0.33	GO:0001104	RNA polymerase II transcription cofactor activity
0.32	GO:0005515	protein binding

0.84	GO:0032039	integrator complex
0.36	GO:0005737	cytoplasm
0.35	GO:0031965	nuclear membrane
0.33	GO:0016592	mediator complex
0.30	GO:0016021	integral component of membrane

tr|T1EQB4|T1EQB4_HELRO
Uncharacterized protein
Search

tr|T1EQB5|T1EQB5_HELRO
Uncharacterized protein
Search

tr|T1EQB6|T1EQB6_HELRO
Uncharacterized protein
Search

tr|T1EQB7|T1EQB7_HELRO
Uncharacterized protein
Search

tr|T1EQB8|T1EQB8_HELRO
Uncharacterized protein
Search

tr|T1EQB9|T1EQB9_HELRO
Uncharacterized protein
Search

0.48	GO:0010255	glucose mediated signaling pathway
0.47	GO:0033363	secretory granule organization
0.45	GO:0016255	attachment of GPI anchor to protein
0.45	GO:0007030	Golgi organization
0.45	GO:0051047	positive regulation of secretion
0.43	GO:0000902	cell morphogenesis
0.42	GO:0006897	endocytosis
0.42	GO:0009306	protein secretion
0.40	GO:0006281	DNA repair
0.40	GO:0006468	protein phosphorylation

0.43	GO:0070403	NAD+ binding
0.42	GO:0004674	protein serine/threonine kinase activity
0.41	GO:0003676	nucleic acid binding
0.41	GO:0008270	zinc ion binding
0.40	GO:0008168	methyltransferase activity
0.40	GO:0016853	isomerase activity
0.39	GO:0003700	DNA binding transcription factor activity
0.38	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding

0.47	GO:0044432	endoplasmic reticulum part
0.46	GO:0005634	nucleus
0.46	GO:0000137	Golgi cis cisterna
0.44	GO:0048476	Holliday junction resolvase complex
0.42	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.39	GO:1902494	catalytic complex
0.38	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.42

GO:0004674

tr|T1EQC0|T1EQC0_HELRO
Uncharacterized protein
Search

tr|T1EQC1|T1EQC1_HELRO
Uncharacterized protein
Search

tr|T1EQC2|T1EQC2_HELRO
Uncharacterized protein
Search

tr|T1EQC3|T1EQC3_HELRO
Uncharacterized protein
Search

tr|T1EQC4|T1EQC4_HELRO
Uncharacterized protein
Search

tr|T1EQC5|T1EQC5_HELRO
Uncharacterized protein
Search

tr|T1EQC6|T1EQC6_HELRO
Uncharacterized protein
Search

tr|T1EQC7|T1EQC7_HELRO
Uncharacterized protein
Search

tr|T1EQC8|T1EQC8_HELRO
Uncharacterized protein
Search

0.74	DnaJ like protein subfamily C member 8

0.85

GO:0030544

Hsp70 protein binding

0.82	GO:0045171	intercellular bridge
0.67	GO:0005654	nucleoplasm
0.66	GO:0005829	cytosol

tr|T1EQC9|T1EQC9_HELRO
Uncharacterized protein
Search

tr|T1EQD0|T1EQD0_HELRO
Uncharacterized protein
Search

tr|T1EQD1|T1EQD1_HELRO
Uncharacterized protein
Search

tr|T1EQD2|T1EQD2_HELRO
Uncharacterized protein
Search

tr|T1EQD3|T1EQD3_HELRO
Uncharacterized protein
Search

0.77	GO:0035725	sodium ion transmembrane transport
0.37	GO:0070207	protein homotrimerization
0.36	GO:0055078	sodium ion homeostasis
0.36	GO:0071467	cellular response to pH
0.36	GO:0050891	multicellular organismal water homeostasis
0.36	GO:0045944	positive regulation of transcription by RNA polymerase II
0.36	GO:0051726	regulation of cell cycle
0.35	GO:0071805	potassium ion transmembrane transport
0.34	GO:0006468	protein phosphorylation

0.81	GO:0005272	sodium channel activity
0.40	GO:0099094	ligand-gated cation channel activity
0.37	GO:0004693	cyclin-dependent protein serine/threonine kinase activity
0.37	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity
0.36	GO:0050699	WW domain binding
0.35	GO:0005267	potassium channel activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.37	GO:0070985	TFIIK complex
0.36	GO:0034706	sodium channel complex
0.36	GO:0005887	integral component of plasma membrane
0.36	GO:0009897	external side of plasma membrane
0.36	GO:0070062	extracellular exosome
0.33	GO:0005737	cytoplasm

0.37

EC:2.7.11.22

GO:0004693

tr|T1EQD4|T1EQD4_HELRO
Uncharacterized protein
Search

tr|T1EQD5|T1EQD5_HELRO
Uncharacterized protein
Search

tr|T1EQD6|T1EQD6_HELRO
Uncharacterized protein
Search

tr|T1EQD7|T1EQD7_HELRO
Uncharacterized protein
Search

tr|T1EQD8|T1EQD8_HELRO
Uncharacterized protein
Search

tr|T1EQD9|T1EQD9_HELRO
Uncharacterized protein
Search

tr|T1EQE0|T1EQE0_HELRO
Uncharacterized protein
Search

tr|T1EQE1|T1EQE1_HELRO
Uncharacterized protein
Search

tr|T1EQE2|T1EQE2_HELRO
Uncharacterized protein
Search

tr|T1EQE3|T1EQE3_HELRO
Uncharacterized protein
Search

tr|T1EQE4|T1EQE4_HELRO
Uncharacterized protein
Search

tr|T1EQE5|T1EQE5_HELRO
Uncharacterized protein
Search

tr|T1EQE6|T1EQE6_HELRO
Uncharacterized protein
Search

tr|T1EQE7|T1EQE7_HELRO
Uncharacterized protein
Search

tr|T1EQE8|T1EQE8_HELRO
Uncharacterized protein
Search

tr|T1EQE9|T1EQE9_HELRO
Uncharacterized protein
Search

tr|T1EQF0|T1EQF0_HELRO
Uncharacterized protein
Search

tr|T1EQF1|T1EQF1_HELRO
Uncharacterized protein
Search

SCN5A

0.92	Sodium voltage-gated channel alpha subunit 5

0.76	GO:0035725	sodium ion transmembrane transport
0.75	GO:0034765	regulation of ion transmembrane transport
0.45	GO:0019228	neuronal action potential
0.45	GO:0086010	membrane depolarization during action potential
0.44	GO:0019233	sensory perception of pain
0.36	GO:0007610	behavior
0.35	GO:0007267	cell-cell signaling
0.35	GO:0002082	regulation of oxidative phosphorylation
0.35	GO:0006110	regulation of glycolytic process
0.35	GO:0006936	muscle contraction

0.83	GO:0005248	voltage-gated sodium channel activity
0.73	GO:0022832	voltage-gated channel activity
0.70	GO:0022839	ion gated channel activity
0.70	GO:0008381	mechanosensitive ion channel activity
0.57	GO:0005509	calcium ion binding
0.34	GO:0044325	ion channel binding
0.34	GO:0050998	nitric-oxide synthase binding
0.34	GO:0030506	ankyrin binding
0.34	GO:0017134	fibroblast growth factor binding
0.34	GO:0097110	scaffold protein binding

0.82	GO:0001518	voltage-gated sodium channel complex
0.35	GO:0014704	intercalated disc
0.34	GO:0030315	T-tubule
0.34	GO:0016328	lateral plasma membrane
0.34	GO:0005901	caveola
0.34	GO:0030018	Z disc
0.33	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0044299	C-fiber
0.33	GO:0009986	cell surface
0.33	GO:0097386	glial cell projection

tr|T1EQF2|T1EQF2_HELRO
Uncharacterized protein
Search

tr|T1EQF3|T1EQF3_HELRO
Uncharacterized protein
Search

tr|T1EQF4|T1EQF4_HELRO
Uncharacterized protein
Search

tr|T1EQF5|T1EQF5_HELRO
Uncharacterized protein
Search

tr|T1EQF6|T1EQF6_HELRO
Uncharacterized protein
Search

tr|T1EQF7|T1EQF7_HELRO
Uncharacterized protein
Search

tr|T1EQF8|T1EQF8_HELRO
Uncharacterized protein
Search

tr|T1EQF9|T1EQF9_HELRO
Uncharacterized protein
Search

tr|T1EQG0|T1EQG0_HELRO
Uncharacterized protein
Search

tr|T1EQG1|T1EQG1_HELRO
Uncharacterized protein
Search

0.54	GO:0099120	socially cooperative development
0.46	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.46	GO:0001708	cell fate specification
0.45	GO:0000027	ribosomal large subunit assembly
0.43	GO:0019954	asexual reproduction
0.39	GO:0006468	protein phosphorylation
0.38	GO:0060255	regulation of macromolecule metabolic process

0.46	GO:0003924	GTPase activity
0.45	GO:0032550	purine ribonucleoside binding
0.45	GO:0019001	guanyl nucleotide binding
0.42	GO:0032555	purine ribonucleotide binding
0.42	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0019843	rRNA binding
0.40	GO:0005515	protein binding
0.39	GO:0004672	protein kinase activity
0.39	GO:0020037	heme binding
0.37	GO:0046872	metal ion binding

0.45	GO:0000792	heterochromatin
0.44	GO:0005730	nucleolus
0.40	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

tr|T1EQG2|T1EQG2_HELRO
Uncharacterized protein
Search

tr|T1EQG3|T1EQG3_HELRO
Uncharacterized protein
Search

tr|T1EQG4|T1EQG4_HELRO
Uncharacterized protein
Search

tr|T1EQG5|T1EQG5_HELRO
Uncharacterized protein
Search

tr|T1EQG6|T1EQG6_HELRO
Uncharacterized protein
Search

tr|T1EQG7|T1EQG7_HELRO
Uncharacterized protein
Search

0.72	GO:0006401	RNA catabolic process
0.62	GO:0006396	RNA processing
0.61	GO:0016071	mRNA metabolic process
0.60	GO:0010629	negative regulation of gene expression
0.41	GO:0016073	snRNA metabolic process
0.39	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic
0.39	GO:0043632	modification-dependent macromolecule catabolic process
0.38	GO:0016072	rRNA metabolic process
0.38	GO:0042254	ribosome biogenesis
0.37	GO:0006399	tRNA metabolic process

0.68	GO:0004654	polyribonucleotide nucleotidyltransferase activity
0.56	GO:0000287	magnesium ion binding
0.54	GO:0003723	RNA binding
0.42	GO:0042802	identical protein binding
0.34	GO:0016787	hydrolase activity

0.62	GO:0000178	exosome (RNase complex)
0.46	GO:0005737	cytoplasm
0.39	GO:0005634	nucleus
0.38	GO:0031974	membrane-enclosed lumen
0.36	GO:0044446	intracellular organelle part

0.68

EC:2.7.7.8

GO:0004654

tr|T1EQG8|T1EQG8_HELRO
Uncharacterized protein
Search

tr|T1EQG9|T1EQG9_HELRO
Uncharacterized protein
Search

tr|T1EQH0|T1EQH0_HELRO
Uncharacterized protein
Search

tr|T1EQH1|T1EQH1_HELRO
Uncharacterized protein
Search

tr|T1EQH2|T1EQH2_HELRO
Uncharacterized protein
Search

0.38	Voltage-dependent L-type calcium channel subunit alpha

0.76	GO:0070588	calcium ion transmembrane transport
0.76	GO:0034765	regulation of ion transmembrane transport
0.42	GO:0086010	membrane depolarization during action potential
0.41	GO:0003012	muscle system process
0.39	GO:0055017	cardiac muscle tissue growth
0.39	GO:0007368	determination of left/right symmetry
0.39	GO:0003143	embryonic heart tube morphogenesis
0.39	GO:0048701	embryonic cranial skeleton morphogenesis
0.39	GO:0070509	calcium ion import
0.38	GO:0008016	regulation of heart contraction

0.81	GO:0005245	voltage-gated calcium channel activity
0.48	GO:0005509	calcium ion binding
0.37	GO:0005249	voltage-gated potassium channel activity

0.80	GO:0005891	voltage-gated calcium channel complex
0.38	GO:0030315	T-tubule
0.37	GO:0031674	I band
0.37	GO:0008076	voltage-gated potassium channel complex
0.35	GO:0048787	presynaptic active zone membrane

tr|T1EQH3|T1EQH3_HELRO
Uncharacterized protein
Search

0.10	Putative voltage-dependent p/q type calcium channel

0.75	GO:0034765	regulation of ion transmembrane transport
0.74	GO:0070588	calcium ion transmembrane transport
0.39	GO:0086010	membrane depolarization during action potential
0.36	GO:0006936	muscle contraction
0.35	GO:0030252	growth hormone secretion
0.35	GO:0060073	micturition
0.35	GO:0086027	AV node cell to bundle of His cell signaling
0.35	GO:0086026	atrial cardiac muscle cell to AV node cell signaling
0.35	GO:0098911	regulation of ventricular cardiac muscle cell action potential
0.35	GO:0035115	embryonic forelimb morphogenesis

0.79	GO:0005245	voltage-gated calcium channel activity
0.38	GO:0005509	calcium ion binding
0.36	GO:1905030	voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential
0.35	GO:0051393	alpha-actinin binding
0.35	GO:0051721	protein phosphatase 2A binding
0.35	GO:0044325	ion channel binding
0.35	GO:0031369	translation initiation factor binding
0.34	GO:0005516	calmodulin binding
0.34	GO:0019904	protein domain specific binding

0.78	GO:0005891	voltage-gated calcium channel complex
0.36	GO:0002095	caveolar macromolecular signaling complex
0.35	GO:0030315	T-tubule
0.35	GO:0043198	dendritic shaft
0.35	GO:0042734	presynaptic membrane
0.35	GO:0030018	Z disc
0.35	GO:0014069	postsynaptic density
0.35	GO:0043025	neuronal cell body
0.34	GO:0045211	postsynaptic membrane
0.34	GO:0016323	basolateral plasma membrane

tr|T1EQH4|T1EQH4_HELRO
Uncharacterized protein
Search

0.73	GO:0070588	calcium ion transmembrane transport
0.70	GO:0034765	regulation of ion transmembrane transport
0.39	GO:0086010	membrane depolarization during action potential
0.39	GO:0035545	determination of left/right asymmetry in nervous system
0.39	GO:0043051	regulation of pharyngeal pumping
0.37	GO:0045989	positive regulation of striated muscle contraction
0.37	GO:0043029	T cell homeostasis
0.37	GO:0050856	regulation of T cell receptor signaling pathway
0.36	GO:0040017	positive regulation of locomotion
0.36	GO:0007601	visual perception

0.77	GO:0005245	voltage-gated calcium channel activity
0.37	GO:0005509	calcium ion binding
0.34	GO:0004672	protein kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.77

GO:0005891

voltage-gated calcium channel complex

tr|T1EQH5|T1EQH5_HELRO
Uncharacterized protein
Search

tr|T1EQH6|T1EQH6_HELRO
Uncharacterized protein
Search

tr|T1EQH7|T1EQH7_HELRO
Uncharacterized protein
Search

tr|T1EQH8|T1EQH8_HELRO
Uncharacterized protein
Search

tr|T1EQH9|T1EQH9_HELRO
Uncharacterized protein
Search

tr|T1EQI0|T1EQI0_HELRO
Uncharacterized protein
Search

tr|T1EQI1|T1EQI1_HELRO
Uncharacterized protein
Search

0.45	GO:0007165	signal transduction
0.40	GO:0034220	ion transmembrane transport
0.39	GO:1903506	regulation of nucleic acid-templated transcription
0.39	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.39	GO:0010468	regulation of gene expression
0.39	GO:0006468	protein phosphorylation

0.49	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.44	GO:0005230	extracellular ligand-gated ion channel activity
0.43	GO:0030246	carbohydrate binding
0.42	GO:0004888	transmembrane signaling receptor activity
0.39	GO:0004672	protein kinase activity
0.39	GO:0046872	metal ion binding
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding

0.41	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|T1EQI2|T1EQI2_HELRO
Uncharacterized protein
Search

tr|T1EQI3|T1EQI3_HELRO
Uncharacterized protein
Search

tr|T1EQI4|T1EQI4_HELRO
Uncharacterized protein
Search

tr|T1EQI5|T1EQI5_HELRO
Uncharacterized protein
Search

tr|T1EQI6|T1EQI6_HELRO
Uncharacterized protein
Search

tr|T1EQI7|T1EQI7_HELRO
Uncharacterized protein
Search

0.41	GO:0050795	regulation of behavior
0.40	GO:0007399	nervous system development
0.38	GO:0006171	cAMP biosynthetic process
0.36	GO:0060399	positive regulation of growth hormone receptor signaling pathway
0.36	GO:0007010	cytoskeleton organization
0.36	GO:0030029	actin filament-based process
0.36	GO:0007165	signal transduction
0.35	GO:0071805	potassium ion transmembrane transport
0.35	GO:0040014	regulation of multicellular organism growth
0.35	GO:0042593	glucose homeostasis

0.53	GO:0003677	DNA binding
0.42	GO:0003682	chromatin binding
0.38	GO:0004016	adenylate cyclase activity
0.37	GO:0016286	small conductance calcium-activated potassium channel activity
0.36	GO:0017048	Rho GTPase binding
0.36	GO:0003779	actin binding
0.36	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.35	GO:1901265	nucleoside phosphate binding
0.35	GO:0036094	small molecule binding
0.34	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

0.59	GO:0005634	nucleus
0.44	GO:0010369	chromocenter
0.41	GO:0030496	midbody
0.35	GO:0005886	plasma membrane
0.34	GO:0005911	cell-cell junction
0.33	GO:0000786	nucleosome
0.33	GO:0019028	viral capsid
0.32	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.38

EC:4.6.1.1

GO:0004016

tr|T1EQI8|T1EQI8_HELRO
Uncharacterized protein
Search

tr|T1EQI9|T1EQI9_HELRO
Uncharacterized protein
Search

tr|T1EQJ0|T1EQJ0_HELRO
Uncharacterized protein
Search

tr|T1EQJ1|T1EQJ1_HELRO
Uncharacterized protein
Search

0.54	mRNA-decapping enzyme 1A

0.84	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA
0.73	GO:0043085	positive regulation of catalytic activity
0.48	GO:0031087	deadenylation-independent decapping of nuclear-transcribed mRNA
0.47	GO:1903608	protein localization to cytoplasmic stress granule
0.37	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
0.32	GO:0055114	oxidation-reduction process

0.75	GO:0008047	enzyme activator activity
0.44	GO:0003729	mRNA binding
0.42	GO:0042802	identical protein binding
0.34	GO:0019894	kinesin binding
0.33	GO:0016787	hydrolase activity
0.32	GO:0016491	oxidoreductase activity

0.50	GO:0000932	P-body
0.44	GO:0005829	cytosol
0.40	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016020	membrane

0.33

GO:0016787

tr|T1EQJ2|T1EQJ2_HELRO
Uncharacterized protein
Search

0.54	GO:0016567	protein ubiquitination
0.52	GO:0023051	regulation of signaling
0.40	GO:0007155	cell adhesion
0.37	GO:0006468	protein phosphorylation
0.37	GO:0006508	proteolysis
0.37	GO:0007165	signal transduction

0.54	GO:0004842	ubiquitin-protein transferase activity
0.43	GO:0003677	DNA binding
0.41	GO:0017124	SH3 domain binding
0.40	GO:0061659	ubiquitin-like protein ligase activity
0.39	GO:0005509	calcium ion binding
0.37	GO:0004672	protein kinase activity
0.37	GO:0016787	hydrolase activity
0.36	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.47	GO:0005634	nucleus
0.44	GO:0070701	mucus layer
0.41	GO:0045121	membrane raft
0.36	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.37	EC:3	GO:0016787
0.54	KEGG:R03876	GO:0004842

tr|T1EQJ3|T1EQJ3_HELRO
Uncharacterized protein
Search

tr|T1EQJ4|T1EQJ4_HELRO
Uncharacterized protein
Search

tr|T1EQJ5|T1EQJ5_HELRO
Uncharacterized protein
Search

tr|T1EQJ6|T1EQJ6_HELRO
Uncharacterized protein
Search

tr|T1EQJ7|T1EQJ7_HELRO
Uncharacterized protein
Search

tr|T1EQJ8|T1EQJ8_HELRO
Uncharacterized protein
Search

0.63	GO:0045859	regulation of protein kinase activity
0.53	GO:0016310	phosphorylation
0.46	GO:0036211	protein modification process
0.43	GO:0044267	cellular protein metabolic process
0.37	GO:0006310	DNA recombination

0.65	GO:0019887	protein kinase regulator activity
0.55	GO:0016301	kinase activity
0.46	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.45	GO:0140096	catalytic activity, acting on a protein
0.44	GO:0032559	adenyl ribonucleotide binding
0.43	GO:0043168	anion binding
0.43	GO:0008144	drug binding
0.39	GO:0003779	actin binding
0.38	GO:0070035	purine NTP-dependent helicase activity
0.37	GO:0042623	ATPase activity, coupled

0.68	GO:0005956	protein kinase CK2 complex
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.46

GO:0016773

tr|T1EQJ9|T1EQJ9_HELRO
Uncharacterized protein
Search

tr|T1EQK0|T1EQK0_HELRO
Uncharacterized protein
Search

tr|T1EQK1|T1EQK1_HELRO
Uncharacterized protein
Search

tr|T1EQK2|T1EQK2_HELRO
Uncharacterized protein
Search

0.44	GO:0036211	protein modification process
0.42	GO:0044267	cellular protein metabolic process
0.40	GO:0016569	covalent chromatin modification
0.40	GO:0006352	DNA-templated transcription, initiation
0.39	GO:0016310	phosphorylation
0.37	GO:0006914	autophagy
0.37	GO:0006281	DNA repair
0.37	GO:0006508	proteolysis
0.37	GO:0046856	phosphatidylinositol dephosphorylation
0.37	GO:0090305	nucleic acid phosphodiester bond hydrolysis

0.43	GO:0140096	catalytic activity, acting on a protein
0.42	GO:0003676	nucleic acid binding
0.40	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.40	GO:0016301	kinase activity
0.39	GO:0032559	adenyl ribonucleotide binding
0.39	GO:0008144	drug binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0004402	histone acetyltransferase activity
0.39	GO:0016788	hydrolase activity, acting on ester bonds
0.38	GO:0046872	metal ion binding

0.38	GO:0048188	Set1C/COMPASS complex
0.36	GO:0005615	extracellular space
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.40

GO:0016773

tr|T1EQK3|T1EQK3_HELRO
Uncharacterized protein
Search

tr|T1EQK4|T1EQK4_HELRO
Uncharacterized protein
Search

0.46	GO:0051568	histone H3-K4 methylation
0.46	GO:0015914	phospholipid transport
0.42	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA
0.40	GO:0043085	positive regulation of catalytic activity
0.40	GO:0007018	microtubule-based movement
0.39	GO:0006351	transcription, DNA-templated
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.47	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.46	GO:0005548	phospholipid transporter activity
0.45	GO:0046872	metal ion binding
0.44	GO:0044212	transcription regulatory region DNA binding
0.41	GO:0008017	microtubule binding
0.40	GO:0008047	enzyme activator activity
0.40	GO:0003777	microtubule motor activity
0.39	GO:0003924	GTPase activity
0.38	GO:0032550	purine ribonucleoside binding
0.38	GO:0019001	guanyl nucleotide binding

0.46	GO:0048188	Set1C/COMPASS complex
0.37	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

tr|T1EQK5|T1EQK5_HELRO
Uncharacterized protein
Search

tr|T1EQK6|T1EQK6_HELRO
Uncharacterized protein
Search

tr|T1EQK7|T1EQK7_HELRO
Uncharacterized protein
Search

CCDC12

0.67	Coiled-coil domain-containing protein 12

0.41

GO:0005515

protein binding

0.30

GO:0044425

membrane part

tr|T1EQK8|T1EQK8_HELRO
Uncharacterized protein
Search

tr|T1EQK9|T1EQK9_HELRO
Uncharacterized protein
Search

0.40

GO:0005515

protein binding

0.30

GO:0044425

membrane part

tr|T1EQL0|T1EQL0_HELRO
Uncharacterized protein
Search

tr|T1EQL1|T1EQL1_HELRO
Uncharacterized protein
Search

tr|T1EQL2|T1EQL2_HELRO
Uncharacterized protein
Search

tr|T1EQL3|T1EQL3_HELRO
Uncharacterized protein
Search

tr|T1EQL4|T1EQL4_HELRO
Uncharacterized protein
Search

tr|T1EQL5|T1EQL5_HELRO
Uncharacterized protein
Search

tr|T1EQL6|T1EQL6_HELRO
Uncharacterized protein
Search

0.64	GO:0001745	compound eye morphogenesis
0.63	GO:0016202	regulation of striated muscle tissue development
0.60	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.50	GO:0006357	regulation of transcription by RNA polymerase II
0.50	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.46	GO:0006413	translational initiation
0.44	GO:0006351	transcription, DNA-templated

0.64	GO:0030165	PDZ domain binding
0.57	GO:0042802	identical protein binding
0.51	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.46	GO:0003743	translation initiation factor activity
0.46	GO:0008270	zinc ion binding
0.45	GO:0003677	DNA binding
0.45	GO:0003924	GTPase activity
0.44	GO:0032550	purine ribonucleoside binding
0.44	GO:0019001	guanyl nucleotide binding
0.39	GO:0032555	purine ribonucleotide binding

0.63	GO:0005913	cell-cell adherens junction
0.62	GO:0016324	apical plasma membrane
0.45	GO:0005634	nucleus
0.44	GO:0005856	cytoskeleton
0.37	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

tr|T1EQL7|T1EQL7_HELRO
Uncharacterized protein
Search

tr|T1EQL8|T1EQL8_HELRO
Uncharacterized protein
Search

tr|T1EQL9|T1EQL9_HELRO
Uncharacterized protein
Search

tr|T1EQM0|T1EQM0_HELRO
Uncharacterized protein
Search

tr|T1EQM1|T1EQM1_HELRO
Uncharacterized protein
Search

0.37

GO:0006313

transposition, DNA-mediated

0.51	GO:0003676	nucleic acid binding
0.42	GO:0046872	metal ion binding
0.37	GO:0004803	transposase activity

tr|T1EQM2|T1EQM2_HELRO
Uncharacterized protein
Search

tr|T1EQM3|T1EQM3_HELRO
Uncharacterized protein
Search

tr|T1EQM4|T1EQM4_HELRO
Uncharacterized protein
Search

tr|T1EQM5|T1EQM5_HELRO
Uncharacterized protein
Search

tr|T1EQM6|T1EQM6_HELRO
Uncharacterized protein
Search

tr|T1EQM7|T1EQM7_HELRO
Uncharacterized protein
Search

0.30

GO:0044425

membrane part

tr|T1EQM8|T1EQM8_HELRO
Uncharacterized protein
Search

tr|T1EQM9|T1EQM9_HELRO
Uncharacterized protein
Search

tr|T1EQN0|T1EQN0_HELRO
Uncharacterized protein
Search

0.41	GO:0007050	cell cycle arrest
0.40	GO:0000413	protein peptidyl-prolyl isomerization
0.40	GO:0000398	mRNA splicing, via spliceosome
0.40	GO:0006367	transcription initiation from RNA polymerase II promoter
0.39	GO:0006950	response to stress
0.39	GO:0002943	tRNA dihydrouridine synthesis
0.38	GO:0051716	cellular response to stimulus
0.38	GO:0006357	regulation of transcription by RNA polymerase II
0.37	GO:0006508	proteolysis
0.37	GO:0006310	DNA recombination

0.48	GO:0032559	adenyl ribonucleotide binding
0.47	GO:0008144	drug binding
0.47	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0045131	pre-mRNA branch point binding
0.41	GO:0140096	catalytic activity, acting on a protein
0.41	GO:0016859	cis-trans isomerase activity
0.40	GO:0008270	zinc ion binding
0.39	GO:0017150	tRNA dihydrouridine synthase activity
0.39	GO:0008289	lipid binding
0.38	GO:0003684	damaged DNA binding

0.40	GO:0005634	nucleus
0.39	GO:0000428	DNA-directed RNA polymerase complex
0.39	GO:0005667	transcription factor complex
0.37	GO:0031974	membrane-enclosed lumen
0.36	GO:0044446	intracellular organelle part
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.41

EC:5.2

GO:0016859

tr|T1EQN1|T1EQN1_HELRO
Uncharacterized protein
Search

0.56	SLIT-ROBO Rho GTPase-activating protein 1

0.75	GO:0043547	positive regulation of GTPase activity
0.61	GO:0007165	signal transduction
0.40	GO:0030336	negative regulation of cell migration
0.40	GO:0021816	extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration
0.39	GO:0046847	filopodium assembly
0.39	GO:0060996	dendritic spine development
0.38	GO:0048812	neuron projection morphogenesis
0.36	GO:0060101	negative regulation of phagocytosis, engulfment
0.36	GO:0070587	regulation of cell-cell adhesion involved in gastrulation
0.35	GO:0022409	positive regulation of cell-cell adhesion

0.76	GO:0005096	GTPase activator activity
0.43	GO:0048365	Rac GTPase binding
0.37	GO:0042803	protein homodimerization activity
0.35	GO:0043621	protein self-association

0.38	GO:0045335	phagocytic vesicle
0.38	GO:0014069	postsynaptic density
0.38	GO:0045211	postsynaptic membrane
0.36	GO:0005829	cytosol
0.36	GO:0016342	catenin complex
0.35	GO:0031966	mitochondrial membrane
0.35	GO:0019866	organelle inner membrane
0.35	GO:0005912	adherens junction
0.34	GO:0005938	cell cortex
0.30	GO:0016021	integral component of membrane

tr|T1EQN2|T1EQN2_HELRO
Uncharacterized protein
Search

tr|T1EQN3|T1EQN3_HELRO
Uncharacterized protein
Search

tr|T1EQN4|T1EQN4_HELRO
Uncharacterized protein
Search

tr|T1EQN5|T1EQN5_HELRO
Uncharacterized protein
Search

tr|T1EQN6|T1EQN6_HELRO
Uncharacterized protein
Search

tr|T1EQN7|T1EQN7_HELRO
Uncharacterized protein
Search

0.64	GO:0006334	nucleosome assembly
0.50	GO:0006468	protein phosphorylation
0.42	GO:0007399	nervous system development
0.39	GO:0120036	plasma membrane bounded cell projection organization
0.39	GO:0048468	cell development
0.37	GO:0045595	regulation of cell differentiation
0.36	GO:0006351	transcription, DNA-templated

0.50	GO:0004672	protein kinase activity
0.47	GO:0003677	DNA binding
0.45	GO:0030554	adenyl nucleotide binding
0.44	GO:0032555	purine ribonucleotide binding
0.44	GO:0008144	drug binding
0.44	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0000786	nucleosome
0.35	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

tr|T1EQN8|T1EQN8_HELRO
Uncharacterized protein
Search

tr|T1EQN9|T1EQN9_HELRO
Uncharacterized protein
Search

tr|T1EQP0|T1EQP0_HELRO
Uncharacterized protein
Search

tr|T1EQP1|T1EQP1_HELRO
Uncharacterized protein
Search

tr|T1EQP2|T1EQP2_HELRO
Uncharacterized protein
Search

tr|T1EQP3|T1EQP3_HELRO
Uncharacterized protein
Search

tr|T1EQP4|T1EQP4_HELRO
Uncharacterized protein
Search

tr|T1EQP5|T1EQP5_HELRO
Uncharacterized protein
Search

tr|T1EQP6|T1EQP6_HELRO
Uncharacterized protein
Search

tr|T1EQP7|T1EQP7_HELRO
Uncharacterized protein
Search

tr|T1EQP8|T1EQP8_HELRO
Uncharacterized protein
Search

tr|T1EQP9|T1EQP9_HELRO
Uncharacterized protein
Search

tr|T1EQQ0|T1EQQ0_HELRO
Uncharacterized protein
Search

tr|T1EQQ1|T1EQQ1_HELRO
Uncharacterized protein
Search

0.60	GO:1900245	positive regulation of MDA-5 signaling pathway
0.59	GO:1900246	positive regulation of RIG-I signaling pathway
0.59	GO:0051151	negative regulation of smooth muscle cell differentiation
0.58	GO:0001955	blood vessel maturation
0.57	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle
0.55	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.55	GO:0045087	innate immune response
0.52	GO:0042742	defense response to bacterium
0.52	GO:0006275	regulation of DNA replication
0.37	GO:0051205	protein insertion into membrane

0.56	GO:0003723	RNA binding
0.52	GO:0003682	chromatin binding
0.37	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.35	GO:0005272	sodium channel activity
0.35	GO:0005509	calcium ion binding
0.34	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.34	GO:0004003	ATP-dependent DNA helicase activity
0.33	GO:0005515	protein binding
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0004672	protein kinase activity

0.53	GO:0031965	nuclear membrane
0.50	GO:0000785	chromatin
0.40	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.37

EC:2.4.2.30

GO:0003950

tr|T1EQQ2|T1EQQ2_HELRO
Uncharacterized protein
Search

tr|T1EQQ3|T1EQQ3_HELRO
Kinase
Search

0.55

Kinase

0.83	GO:0032958	inositol phosphate biosynthetic process
0.57	GO:0016310	phosphorylation
0.44	GO:0048815	hermaphrodite genitalia morphogenesis

0.60	GO:0016301	kinase activity
0.33	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032553	ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0046872	metal ion binding
0.32	GO:0003676	nucleic acid binding

0.30

GO:0031224

intrinsic component of membrane

0.33

GO:0016773

tr|T1EQQ4|T1EQQ4_HELRO
Hexosyltransferase
Search

0.22	Hexosyltransferase

0.74

GO:0006486

protein glycosylation

0.81

GO:0008378

galactosyltransferase activity

0.74	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

0.81

EC:2.4.1

GO:0008378

tr|T1EQQ5|T1EQQ5_HELRO
Uncharacterized protein
Search

tr|T1EQQ6|T1EQQ6_HELRO
Uncharacterized protein
Search

tr|T1EQQ7|T1EQQ7_HELRO
Uncharacterized protein
Search

tr|T1EQQ8|T1EQQ8_HELRO
Uncharacterized protein
Search

tr|T1EQQ9|T1EQQ9_HELRO
Uncharacterized protein
Search

tr|T1EQR0|T1EQR0_HELRO
Uncharacterized protein
Search

tr|T1EQR1|T1EQR1_HELRO
Uncharacterized protein
Search

tr|T1EQR2|T1EQR2_HELRO
Uncharacterized protein
Search

tr|T1EQR3|T1EQR3_HELRO
Uncharacterized protein
Search

tr|T1EQR4|T1EQR4_HELRO
Uncharacterized protein
Search

tr|T1EQR5|T1EQR5_HELRO
Uncharacterized protein
Search

tr|T1EQR6|T1EQR6_HELRO
Uncharacterized protein
Search

tr|T1EQR7|T1EQR7_HELRO
Uncharacterized protein
Search

0.66

GO:0005576

extracellular region

tr|T1EQR8|T1EQR8_HELRO
Uncharacterized protein
Search

tr|T1EQR9|T1EQR9_HELRO
Uncharacterized protein
Search

tr|T1EQS0|T1EQS0_HELRO
Uncharacterized protein
Search

tr|T1EQS1|T1EQS1_HELRO
Uncharacterized protein
Search

0.44	GO:0000256	allantoin catabolic process
0.42	GO:0010468	regulation of gene expression
0.41	GO:1903506	regulation of nucleic acid-templated transcription
0.41	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.40	GO:0036211	protein modification process
0.39	GO:0044267	cellular protein metabolic process
0.39	GO:0016310	phosphorylation
0.39	GO:0051726	regulation of cell cycle
0.38	GO:0043085	positive regulation of catalytic activity
0.38	GO:0016192	vesicle-mediated transport

0.45	GO:0004037	allantoicase activity
0.43	GO:0046982	protein heterodimerization activity
0.41	GO:0003700	DNA binding transcription factor activity
0.41	GO:0004693	cyclin-dependent protein serine/threonine kinase activity
0.40	GO:0003676	nucleic acid binding
0.39	GO:0000829	inositol heptakisphosphate kinase activity
0.38	GO:0008047	enzyme activator activity
0.38	GO:0097367	carbohydrate derivative binding
0.38	GO:0030554	adenyl nucleotide binding
0.37	GO:0008144	drug binding

0.45	GO:0016602	CCAAT-binding factor complex
0.38	GO:0005829	cytosol
0.36	GO:0031463	Cul3-RING ubiquitin ligase complex
0.36	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex
0.36	GO:0017053	transcriptional repressor complex
0.36	GO:0032432	actin filament bundle
0.35	GO:0071564	npBAF complex
0.35	GO:0005884	actin filament
0.34	GO:0005840	ribosome
0.34	GO:0005739	mitochondrion

0.45	EC:3.5.3.4	GO:0004037
0.45	KEGG:R02422	GO:0004037

tr|T1EQS2|T1EQS2_HELRO
Uncharacterized protein
Search

tr|T1EQS3|T1EQS3_HELRO
Uncharacterized protein
Search

0.40	GO:0005975	carbohydrate metabolic process
0.38	GO:0031323	regulation of cellular metabolic process
0.38	GO:0080090	regulation of primary metabolic process
0.38	GO:0060255	regulation of macromolecule metabolic process
0.38	GO:0051171	regulation of nitrogen compound metabolic process
0.38	GO:0006508	proteolysis
0.38	GO:0071854	cell wall macromolecule catabolic process involved in fungal-type cell wall disassembly
0.38	GO:0009889	regulation of biosynthetic process
0.38	GO:0006351	transcription, DNA-templated
0.37	GO:0009057	macromolecule catabolic process

0.42	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.39	GO:0030246	carbohydrate binding
0.38	GO:0046872	metal ion binding
0.38	GO:0004175	endopeptidase activity
0.38	GO:0003677	DNA binding
0.38	GO:0070001	aspartic-type peptidase activity
0.37	GO:0004622	lysophospholipase activity
0.37	GO:0008144	drug binding
0.37	GO:0035064	methylated histone binding
0.36	GO:0001104	RNA polymerase II transcription cofactor activity

0.39	GO:0005576	extracellular region
0.39	GO:0005634	nucleus
0.36	GO:0009277	fungal-type cell wall
0.36	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0000324	fungal-type vacuole
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

0.42	EC:3.2.1	GO:0004553
0.36	KEGG:R03532	GO:0004601

tr|T1EQS4|T1EQS4_HELRO
Uncharacterized protein
Search

tr|T1EQS5|T1EQS5_HELRO
Uncharacterized protein
Search

tr|T1EQS6|T1EQS6_HELRO
Uncharacterized protein
Search

0.42	GO:0006661	phosphatidylinositol biosynthetic process
0.42	GO:1903506	regulation of nucleic acid-templated transcription
0.42	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.42	GO:0010468	regulation of gene expression
0.38	GO:0043412	macromolecule modification
0.37	GO:0044267	cellular protein metabolic process
0.36	GO:0016310	phosphorylation
0.36	GO:0006325	chromatin organization
0.36	GO:0016070	RNA metabolic process
0.35	GO:0065009	regulation of molecular function

0.43	GO:0003700	DNA binding transcription factor activity
0.38	GO:0003676	nucleic acid binding
0.38	GO:0004672	protein kinase activity
0.37	GO:0046872	metal ion binding
0.37	GO:0030554	adenyl nucleotide binding
0.37	GO:0097367	carbohydrate derivative binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0008144	drug binding
0.36	GO:0098772	molecular function regulator
0.35	GO:0005515	protein binding

0.44	GO:0070772	PAS complex
0.41	GO:0005634	nucleus
0.39	GO:0034708	methyltransferase complex
0.39	GO:0070013	intracellular organelle lumen
0.35	GO:0033202	DNA helicase complex
0.35	GO:0000785	chromatin
0.34	GO:0005856	cytoskeleton
0.34	GO:0034066	RIC1-RGP1 guanyl-nucleotide exchange factor complex
0.34	GO:1904949	ATPase complex
0.34	GO:0032541	cortical endoplasmic reticulum

0.35	EC:3	GO:0016787
0.33	KEGG:R03876	GO:0004842

tr|T1EQS7|T1EQS7_HELRO
Uncharacterized protein
Search

tr|T1EQS8|T1EQS8_HELRO
Uncharacterized protein
Search

tr|T1EQS9|T1EQS9_HELRO
Uncharacterized protein
Search

tr|T1EQT0|T1EQT0_HELRO
Uncharacterized protein
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tr|T1EQT1|T1EQT1_HELRO
Uncharacterized protein
Search

0.47	GO:0016567	protein ubiquitination
0.45	GO:1903506	regulation of nucleic acid-templated transcription
0.45	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.45	GO:0010468	regulation of gene expression
0.40	GO:0016070	RNA metabolic process
0.40	GO:0010467	gene expression
0.39	GO:0034654	nucleobase-containing compound biosynthetic process
0.38	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity
0.38	GO:0042147	retrograde transport, endosome to Golgi
0.38	GO:0016310	phosphorylation

0.47	GO:0004842	ubiquitin-protein transferase activity
0.46	GO:0003700	DNA binding transcription factor activity
0.42	GO:0000829	inositol heptakisphosphate kinase activity
0.39	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.39	GO:0008270	zinc ion binding
0.39	GO:0003676	nucleic acid binding
0.38	GO:0016874	ligase activity
0.38	GO:0004534	5'-3' exoribonuclease activity
0.38	GO:0004674	protein serine/threonine kinase activity
0.38	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity

0.44	GO:0005634	nucleus
0.39	GO:0030906	retromer, cargo-selective complex
0.38	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.37	GO:0033202	DNA helicase complex
0.36	GO:0000785	chromatin
0.36	GO:0005829	cytosol
0.36	GO:0043233	organelle lumen
0.36	GO:1904949	ATPase complex
0.30	GO:0016021	integral component of membrane

0.39	EC:2.7.7.6	GO:0003899
0.47	KEGG:R03876	GO:0004842

tr|T1EQT2|T1EQT2_HELRO
Uncharacterized protein
Search

0.77	GO:0035023	regulation of Rho protein signal transduction
0.66	GO:0065009	regulation of molecular function
0.54	GO:0035556	intracellular signal transduction
0.44	GO:0048332	mesoderm morphogenesis
0.43	GO:0009887	animal organ morphogenesis
0.36	GO:0010769	regulation of cell morphogenesis involved in differentiation
0.35	GO:0010977	negative regulation of neuron projection development
0.35	GO:0015074	DNA integration
0.35	GO:0043065	positive regulation of apoptotic process
0.34	GO:0060438	trachea development

0.77	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.33	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.33	GO:0046872	metal ion binding
0.33	GO:0003676	nucleic acid binding
0.33	GO:0003964	RNA-directed DNA polymerase activity
0.33	GO:0070001	aspartic-type peptidase activity
0.33	GO:0004519	endonuclease activity
0.33	GO:0004175	endopeptidase activity

0.41	GO:0005622	intracellular
0.35	GO:0070062	extracellular exosome
0.33	GO:0043228	non-membrane-bounded organelle
0.30	GO:0016020	membrane

0.33

GO:0003964

tr|T1EQT3|T1EQT3_HELRO
Uncharacterized protein
Search

tr|T1EQT4|T1EQT4_HELRO
Uncharacterized protein
Search

0.72	LPS-induced TNF-alpha factor

0.30

GO:0044425

membrane part

tr|T1EQT5|T1EQT5_HELRO
Uncharacterized protein
Search

tr|T1EQT6|T1EQT6_HELRO
Uncharacterized protein
Search

tr|T1EQT7|T1EQT7_HELRO
Uncharacterized protein
Search

tr|T1EQT8|T1EQT8_HELRO
Uncharacterized protein
Search

tr|T1EQT9|T1EQT9_HELRO
Uncharacterized protein
Search

0.76	GO:0000103	sulfate assimilation
0.58	GO:0050428	3'-phosphoadenosine 5'-phosphosulfate biosynthetic process
0.57	GO:0016310	phosphorylation
0.40	GO:0070814	hydrogen sulfide biosynthetic process
0.35	GO:0001501	skeletal system development
0.34	GO:0007596	blood coagulation
0.33	GO:0048513	animal organ development
0.32	GO:0055114	oxidation-reduction process

0.80	GO:0004020	adenylylsulfate kinase activity
0.76	GO:0004781	sulfate adenylyltransferase (ATP) activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0042803	protein homodimerization activity
0.33	GO:0051287	NAD binding
0.33	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

0.35	GO:0009336	sulfate adenylyltransferase complex (ATP)
0.33	GO:0005829	cytosol
0.32	GO:0005634	nucleus

0.80

EC:2.7.1.25

GO:0004020

tr|T1EQU0|T1EQU0_HELRO
Uncharacterized protein
Search

tr|T1EQU1|T1EQU1_HELRO
Uncharacterized protein
Search

tr|T1EQU3|T1EQU3_HELRO
Uncharacterized protein
Search

tr|T1EQU4|T1EQU4_HELRO
Uncharacterized protein
Search

tr|T1EQU5|T1EQU5_HELRO
Uncharacterized protein
Search

0.46	GO:0007020	microtubule nucleation
0.40	GO:0006325	chromatin organization
0.40	GO:0065007	biological regulation
0.39	GO:0036211	protein modification process
0.38	GO:0051641	cellular localization
0.38	GO:0044267	cellular protein metabolic process
0.38	GO:0016192	vesicle-mediated transport
0.37	GO:0033036	macromolecule localization
0.37	GO:0051716	cellular response to stimulus
0.37	GO:0015833	peptide transport

0.47	GO:0043015	gamma-tubulin binding
0.41	GO:0003676	nucleic acid binding
0.39	GO:0140096	catalytic activity, acting on a protein
0.38	GO:0097367	carbohydrate derivative binding
0.38	GO:0043168	anion binding
0.38	GO:0003700	DNA binding transcription factor activity
0.38	GO:0008144	drug binding
0.38	GO:0070052	collagen V binding
0.38	GO:0030554	adenyl nucleotide binding
0.37	GO:0016859	cis-trans isomerase activity

0.46	GO:0000922	spindle pole
0.45	GO:0005634	nucleus
0.45	GO:0005815	microtubule organizing center
0.40	GO:0070013	intracellular organelle lumen
0.37	GO:0000793	condensed chromosome
0.37	GO:0044427	chromosomal part
0.36	GO:0044444	cytoplasmic part
0.36	GO:1990234	transferase complex
0.36	GO:0044421	extracellular region part
0.35	GO:0032155	cell division site part

0.37

EC:5.2

GO:0016859

tr|T1EQU6|T1EQU6_HELRO
Uncharacterized protein
Search

tr|T1EQU7|T1EQU7_HELRO
Uncharacterized protein
Search

0.59	GO:0035023	regulation of Rho protein signal transduction
0.54	GO:0065009	regulation of molecular function
0.42	GO:0007018	microtubule-based movement
0.41	GO:0006357	regulation of transcription by RNA polymerase II
0.41	GO:0006351	transcription, DNA-templated
0.40	GO:1903474	anchoring of the mitotic actomyosin contractile ring to the plasma membrane
0.39	GO:0006379	mRNA cleavage
0.39	GO:0006378	mRNA polyadenylation
0.38	GO:0001522	pseudouridine synthesis
0.37	GO:0007165	signal transduction

0.59	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.44	GO:0003712	transcription cofactor activity
0.43	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.43	GO:0005096	GTPase activator activity
0.42	GO:0003777	microtubule motor activity
0.40	GO:0000993	RNA polymerase II core binding
0.39	GO:0046872	metal ion binding
0.39	GO:0003676	nucleic acid binding
0.39	GO:0035615	clathrin adaptor activity
0.38	GO:0008528	G-protein coupled peptide receptor activity

0.43	GO:0044451	nucleoplasm part
0.41	GO:0043234	protein complex
0.38	GO:0005905	clathrin-coated pit
0.37	GO:0048475	coated membrane
0.35	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.38

EC:5.4.99.12

GO:0009982

tr|T1EQU8|T1EQU8_HELRO
Uncharacterized protein
Search

tr|T1EQU9|T1EQU9_HELRO
Uncharacterized protein
Search

0.40

GO:0046872

metal ion binding

0.30

GO:0044425

membrane part

tr|T1EQV0|T1EQV0_HELRO
Uncharacterized protein
Search

tr|T1EQV1|T1EQV1_HELRO
Uncharacterized protein
Search

tr|T1EQV2|T1EQV2_HELRO
Uncharacterized protein
Search

tr|T1EQV3|T1EQV3_HELRO
Uncharacterized protein
Search

0.40	GO:0006352	DNA-templated transcription, initiation
0.36	GO:2001141	regulation of RNA biosynthetic process
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression
0.35	GO:0006886	intracellular protein transport
0.35	GO:0043044	ATP-dependent chromatin remodeling
0.34	GO:0035023	regulation of Rho protein signal transduction
0.34	GO:0006366	transcription by RNA polymerase II
0.33	GO:0065009	regulation of molecular function

0.75	GO:0045735	nutrient reservoir activity
0.40	GO:0046982	protein heterodimerization activity
0.38	GO:0003712	transcription cofactor activity
0.35	GO:0042393	histone binding
0.34	GO:0046872	metal ion binding
0.34	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.34	GO:0043565	sequence-specific DNA binding
0.34	GO:0004386	helicase activity
0.34	GO:0003700	DNA binding transcription factor activity
0.33	GO:0016887	ATPase activity

0.42	GO:0046695	SLIK (SAGA-like) complex
0.42	GO:0000124	SAGA complex
0.41	GO:0005669	transcription factor TFIID complex
0.36	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0005938	cell cortex
0.35	GO:0016514	SWI/SNF complex
0.34	GO:0005672	transcription factor TFIIA complex
0.30	GO:0016020	membrane

0.33

EC:3.6.1.3

GO:0016887

tr|T1EQV4|T1EQV4_HELRO
Uncharacterized protein
Search

tr|T1EQV5|T1EQV5_HELRO
Uncharacterized protein
Search

0.34	Cytochrome c oxidase subunit 3

0.75	GO:0019646	aerobic electron transport chain
0.63	GO:1902600	hydrogen ion transmembrane transport

0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity

0.61	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.65

EC:1.9.3

GO:0016676

tr|T1EQV6|T1EQV6_HELRO
Uncharacterized protein
Search

tr|T1EQV7|T1EQV7_HELRO
Uncharacterized protein
Search

0.36	GO:0006357	regulation of transcription by RNA polymerase II
0.35	GO:0030042	actin filament depolymerization

0.51	GO:0003676	nucleic acid binding
0.36	GO:0008134	transcription factor binding
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0003700	DNA binding transcription factor activity
0.34	GO:0003779	actin binding

0.54	GO:0005634	nucleus
0.36	GO:0005667	transcription factor complex
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:1902494	catalytic complex
0.34	GO:0015629	actin cytoskeleton
0.34	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

tr|T1EQV8|T1EQV8_HELRO
Uncharacterized protein
Search

0.48	GO:0036211	protein modification process
0.45	GO:0051276	chromosome organization
0.45	GO:0044267	cellular protein metabolic process
0.45	GO:0006914	autophagy
0.44	GO:0016310	phosphorylation
0.43	GO:0031152	aggregation involved in sorocarp development
0.42	GO:0043414	macromolecule methylation
0.41	GO:2001141	regulation of RNA biosynthetic process
0.41	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.41	GO:0010468	regulation of gene expression

0.47	GO:0004672	protein kinase activity
0.45	GO:0018024	histone-lysine N-methyltransferase activity
0.44	GO:0030554	adenyl nucleotide binding
0.44	GO:0032555	purine ribonucleotide binding
0.44	GO:0008144	drug binding
0.44	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0004003	ATP-dependent DNA helicase activity
0.41	GO:0044212	transcription regulatory region DNA binding
0.41	GO:0003700	DNA binding transcription factor activity
0.41	GO:0043138	3'-5' DNA helicase activity

0.47	GO:1990316	Atg1/ULK1 kinase complex
0.44	GO:0005634	nucleus
0.42	GO:0020011	apicoplast
0.41	GO:0034708	methyltransferase complex
0.39	GO:0031974	membrane-enclosed lumen
0.38	GO:0005829	cytosol
0.38	GO:0005694	chromosome
0.37	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.45

EC:2.1.1.43

GO:0018024

tr|T1EQV9|T1EQV9_HELRO
Uncharacterized protein
Search

tr|T1EQW0|T1EQW0_HELRO
Uncharacterized protein
Search

tr|T1EQW1|T1EQW1_HELRO
Uncharacterized protein
Search

0.44

GO:0035556

intracellular signal transduction

0.52

GO:0046872

metal ion binding

0.37

GO:0005622

intracellular

tr|T1EQW2|T1EQW2_HELRO
Uncharacterized protein
Search

tr|T1EQW3|T1EQW3_HELRO
Uncharacterized protein
Search

tr|T1EQW4|T1EQW4_HELRO
Uncharacterized protein
Search

tr|T1EQW5|T1EQW5_HELRO
Uncharacterized protein
Search

tr|T1EQW6|T1EQW6_HELRO
Uncharacterized protein
Search

tr|T1EQW7|T1EQW7_HELRO
Uncharacterized protein
Search

tr|T1EQW8|T1EQW8_HELRO
Uncharacterized protein
Search

tr|T1EQW9|T1EQW9_HELRO
Uncharacterized protein
Search

0.54

GO:0046872

metal ion binding

0.30

GO:0044425

membrane part

tr|T1EQX0|T1EQX0_HELRO
Uncharacterized protein
Search

tr|T1EQX1|T1EQX1_HELRO
Uncharacterized protein
Search

tr|T1EQX2|T1EQX2_HELRO
Uncharacterized protein
Search

tr|T1EQX3|T1EQX3_HELRO
Uncharacterized protein
Search

tr|T1EQX4|T1EQX4_HELRO
Uncharacterized protein
Search

tr|T1EQX5|T1EQX5_HELRO
Uncharacterized protein
Search

tr|T1EQX6|T1EQX6_HELRO
Uncharacterized protein
Search

tr|T1EQX7|T1EQX7_HELRO
Uncharacterized protein
Search

tr|T1EQX8|T1EQX8_HELRO
Uncharacterized protein
Search

tr|T1EQX9|T1EQX9_HELRO
Uncharacterized protein
Search

0.67	GO:0035725	sodium ion transmembrane transport
0.56	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic

0.70	GO:0005272	sodium channel activity
0.58	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.43	GO:0003676	nucleic acid binding

0.30

GO:0031224

intrinsic component of membrane

0.58

EC:3.1.26.4

GO:0004523

tr|T1EQY0|T1EQY0_HELRO
Uncharacterized protein
Search

tr|T1EQY1|T1EQY1_HELRO
Uncharacterized protein
Search

tr|T1EQY2|T1EQY2_HELRO
Uncharacterized protein
Search

tr|T1EQY3|T1EQY3_HELRO
Uncharacterized protein
Search

tr|T1EQY4|T1EQY4_HELRO
Uncharacterized protein
Search

tr|T1EQY5|T1EQY5_HELRO
Uncharacterized protein
Search

tr|T1EQY6|T1EQY6_HELRO
Uncharacterized protein
Search

tr|T1EQY7|T1EQY7_HELRO
Uncharacterized protein
Search

tr|T1EQY8|T1EQY8_HELRO
Uncharacterized protein
Search

tr|T1EQY9|T1EQY9_HELRO
Uncharacterized protein
Search

tr|T1EQZ0|T1EQZ0_HELRO
Uncharacterized protein
Search

tr|T1EQZ1|T1EQZ1_HELRO
Uncharacterized protein
Search

tr|T1EQZ2|T1EQZ2_HELRO
Uncharacterized protein
Search

tr|T1EQZ3|T1EQZ3_HELRO
Uncharacterized protein
Search

0.12	Transposase

0.38	GO:0051607	defense response to virus
0.37	GO:0015074	DNA integration
0.36	GO:0006310	DNA recombination
0.36	GO:0022900	electron transport chain
0.36	GO:0007165	signal transduction

0.50	GO:0003676	nucleic acid binding
0.37	GO:0046872	metal ion binding
0.37	GO:0020037	heme binding
0.36	GO:0009055	electron transfer activity
0.36	GO:0004871	signal transducer activity
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0019001	guanyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.36	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

tr|T1EQZ4|T1EQZ4_HELRO
Uncharacterized protein
Search

tr|T1EQZ5|T1EQZ5_HELRO
Uncharacterized protein
Search

PNPLA7B

0.73	Patatin-like phospholipase domain containing 7a

0.70	GO:0016042	lipid catabolic process
0.43	GO:0046470	phosphatidylcholine metabolic process
0.41	GO:0032502	developmental process

0.52	GO:0004622	lysophospholipase activity
0.33	GO:0008270	zinc ion binding
0.32	GO:0003677	DNA binding

0.44	GO:0005783	endoplasmic reticulum
0.40	GO:0005765	lysosomal membrane
0.40	GO:0031965	nuclear membrane
0.36	GO:0031966	mitochondrial membrane
0.36	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.52

EC:3.1.1.5

GO:0004622

tr|T1EQZ6|T1EQZ6_HELRO
Uncharacterized protein
Search

0.58	Endonuclease exonuclease phosphatase domain containing protein

0.64	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.49	GO:0006278	RNA-dependent DNA biosynthetic process

0.69	GO:0004527	exonuclease activity
0.66	GO:0004519	endonuclease activity
0.50	GO:0003964	RNA-directed DNA polymerase activity

0.50

GO:0003964

tr|T1EQZ7|T1EQZ7_HELRO
Uncharacterized protein
Search

0.68	Patatin-like phospholipase domain-containing protein 7

0.65	GO:0016042	lipid catabolic process
0.57	GO:0046470	phosphatidylcholine metabolic process
0.44	GO:0032502	developmental process
0.42	GO:0030514	negative regulation of BMP signaling pathway
0.40	GO:0120036	plasma membrane bounded cell projection organization
0.38	GO:0032501	multicellular organismal process

0.64

GO:0004622

lysophospholipase activity

0.47	GO:0005783	endoplasmic reticulum
0.37	GO:0005765	lysosomal membrane
0.36	GO:0031965	nuclear membrane
0.34	GO:0031966	mitochondrial membrane
0.30	GO:0016021	integral component of membrane

0.64

EC:3.1.1.5

GO:0004622

tr|T1EQZ8|T1EQZ8_HELRO
Uncharacterized protein
Search

tr|T1EQZ9|T1EQZ9_HELRO
Uncharacterized protein
Search

0.78	GO:0008203	cholesterol metabolic process
0.68	GO:0016042	lipid catabolic process
0.50	GO:0006641	triglyceride metabolic process
0.47	GO:0046339	diacylglycerol metabolic process
0.44	GO:0001676	long-chain fatty acid metabolic process
0.42	GO:0072329	monocarboxylic acid catabolic process
0.38	GO:0006363	termination of RNA polymerase I transcription
0.38	GO:0006361	transcription initiation from RNA polymerase I promoter
0.34	GO:0007565	female pregnancy
0.33	GO:0042493	response to drug

0.71	GO:0016298	lipase activity
0.44	GO:0052689	carboxylic ester hydrolase activity
0.44	GO:0019901	protein kinase binding
0.41	GO:0017171	serine hydrolase activity
0.38	GO:0042134	rRNA primary transcript binding
0.33	GO:0046983	protein dimerization activity
0.33	GO:0043565	sequence-specific DNA binding
0.32	GO:0003700	DNA binding transcription factor activity
0.32	GO:0046872	metal ion binding

0.50	GO:0005811	lipid droplet
0.45	GO:0005829	cytosol
0.38	GO:0005901	caveola
0.35	GO:0005634	nucleus
0.35	GO:0005739	mitochondrion
0.33	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane

0.71	EC:3.1.1	GO:0016298
0.44	KEGG:R00630	GO:0052689

tr|T1ER00|T1ER00_HELRO
Uncharacterized protein
Search

tr|T1ER01|T1ER01_HELRO
Uncharacterized protein
Search

0.63	GO:0006468	protein phosphorylation
0.41	GO:0070817	P-TEFb-cap methyltransferase complex localization
0.41	GO:0045860	positive regulation of protein kinase activity
0.40	GO:0036031	recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex
0.40	GO:1905864	regulation of Atg1/ULK1 kinase complex assembly
0.40	GO:0034402	recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex
0.40	GO:0051726	regulation of cell cycle
0.39	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter
0.39	GO:0006360	transcription by RNA polymerase I
0.38	GO:0031334	positive regulation of protein complex assembly

0.64	GO:0004672	protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0030295	protein kinase activator activity
0.37	GO:0030247	polysaccharide binding
0.37	GO:0060089	molecular transducer activity
0.36	GO:0003714	transcription corepressor activity
0.35	GO:0045296	cadherin binding

0.42	GO:0070985	TFIIK complex
0.40	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex
0.38	GO:0000790	nuclear chromatin
0.37	GO:0005829	cytosol
0.34	GO:0031252	cell leading edge
0.34	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0005886	plasma membrane
0.33	GO:0051286	cell tip
0.33	GO:0043332	mating projection tip
0.33	GO:0032153	cell division site

0.33

EC:1.3.1.74

GO:0032440

tr|T1ER02|T1ER02_HELRO
Uncharacterized protein
Search

tr|T1ER03|T1ER03_HELRO
Uncharacterized protein
Search

0.44	GO:0043412	macromolecule modification
0.43	GO:0090481	pyrimidine nucleotide-sugar transmembrane transport
0.41	GO:0000256	allantoin catabolic process
0.41	GO:0019538	protein metabolic process
0.40	GO:0006325	chromatin organization
0.40	GO:0006396	RNA processing
0.39	GO:0034219	carbohydrate transmembrane transport
0.39	GO:0051674	localization of cell
0.39	GO:0006928	movement of cell or subcellular component
0.38	GO:0016310	phosphorylation

0.43	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.43	GO:0009982	pseudouridine synthase activity
0.43	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity
0.42	GO:0004037	allantoicase activity
0.42	GO:0003723	RNA binding
0.41	GO:0044212	transcription regulatory region DNA binding
0.40	GO:0004672	protein kinase activity
0.40	GO:0004180	carboxypeptidase activity
0.39	GO:0030554	adenyl nucleotide binding
0.39	GO:0032555	purine ribonucleotide binding

0.42	GO:0048188	Set1C/COMPASS complex
0.39	GO:0005794	Golgi apparatus
0.30	GO:0031224	intrinsic component of membrane

0.43	EC:5.4.99.12	GO:0009982
0.42	KEGG:R02422	GO:0004037

tr|T1ER04|T1ER04_HELRO
Uncharacterized protein
Search

0.53

GO:0007186

G-protein coupled receptor signaling pathway

0.53

GO:0004930

G-protein coupled receptor activity

0.30

GO:0044425

membrane part

tr|T1ER05|T1ER05_HELRO
Uncharacterized protein
Search

tr|T1ER06|T1ER06_HELRO
Uncharacterized protein
Search

0.46	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.45	GO:2001141	regulation of RNA biosynthetic process
0.45	GO:0010468	regulation of gene expression
0.43	GO:0016570	histone modification
0.42	GO:0006334	nucleosome assembly
0.42	GO:0018205	peptidyl-lysine modification
0.42	GO:0006475	internal protein amino acid acetylation
0.40	GO:0030154	cell differentiation
0.40	GO:0010557	positive regulation of macromolecule biosynthetic process
0.40	GO:0031328	positive regulation of cellular biosynthetic process

0.45	GO:0046872	metal ion binding
0.44	GO:0003700	DNA binding transcription factor activity
0.44	GO:0003677	DNA binding
0.42	GO:0004402	histone acetyltransferase activity
0.39	GO:0001067	regulatory region nucleic acid binding
0.39	GO:0140096	catalytic activity, acting on a protein
0.39	GO:0005096	GTPase activator activity
0.39	GO:0016491	oxidoreductase activity
0.38	GO:0008061	chitin binding
0.38	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting

0.48	GO:0005634	nucleus
0.41	GO:0000786	nucleosome
0.37	GO:0043234	protein complex
0.36	GO:0070013	intracellular organelle lumen
0.36	GO:0005576	extracellular region
0.36	GO:0015629	actin cytoskeleton
0.36	GO:0045180	basal cortex
0.36	GO:0120114	Sm-like protein family complex
0.35	GO:0044430	cytoskeletal part
0.35	GO:0030018	Z disc

0.42

EC:2.3.1.48

GO:0004402

tr|T1ER07|T1ER07_HELRO
Uncharacterized protein
Search

tr|T1ER08|T1ER08_HELRO
Uncharacterized protein
Search

0.30

GO:0044425

membrane part

tr|T1ER09|T1ER09_HELRO
Uncharacterized protein
Search

tr|T1ER10|T1ER10_HELRO
Uncharacterized protein
Search

tr|T1ER11|T1ER11_HELRO
Uncharacterized protein
Search

tr|T1ER12|T1ER12_HELRO
Uncharacterized protein
Search

tr|T1ER13|T1ER13_HELRO
Uncharacterized protein
Search

tr|T1ER14|T1ER14_HELRO
Uncharacterized protein
Search

tr|T1ER15|T1ER15_HELRO
Uncharacterized protein
Search

tr|T1ER16|T1ER16_HELRO
Uncharacterized protein
Search

0.44	Xylosyltransferase oxt

0.51

GO:0016740

transferase activity

0.51

GO:0016740

tr|T1ER17|T1ER17_HELRO
Uncharacterized protein
Search

tr|T1ER18|T1ER18_HELRO
Uncharacterized protein
Search

tr|T1ER19|T1ER19_HELRO
Uncharacterized protein
Search

tr|T1ER20|T1ER20_HELRO
Uncharacterized protein
Search

tr|T1ER21|T1ER21_HELRO
Uncharacterized protein
Search

tr|T1ER22|T1ER22_HELRO
Uncharacterized protein
Search

tr|T1ER23|T1ER23_HELRO
Uncharacterized protein
Search

tr|T1ER24|T1ER24_HELRO
Uncharacterized protein
Search

tr|T1ER25|T1ER25_HELRO
Uncharacterized protein
Search

tr|T1ER26|T1ER26_HELRO
Uncharacterized protein
Search

tr|T1ER27|T1ER27_HELRO
Uncharacterized protein
Search

0.55	GO:0045944	positive regulation of transcription by RNA polymerase II
0.53	GO:1903861	positive regulation of dendrite extension
0.52	GO:0050775	positive regulation of dendrite morphogenesis
0.52	GO:0007026	negative regulation of microtubule depolymerization
0.49	GO:0035074	pupation
0.49	GO:0035626	juvenile hormone mediated signaling pathway
0.48	GO:0035073	pupariation
0.48	GO:0006366	transcription by RNA polymerase II
0.48	GO:0000122	negative regulation of transcription by RNA polymerase II
0.48	GO:0035023	regulation of Rho protein signal transduction

0.51	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.49	GO:0043565	sequence-specific DNA binding
0.48	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.45	GO:0003707	steroid hormone receptor activity
0.44	GO:0044212	transcription regulatory region DNA binding
0.43	GO:0008270	zinc ion binding
0.43	GO:0046982	protein heterodimerization activity
0.43	GO:0008134	transcription factor binding
0.43	GO:0003690	double-stranded DNA binding

0.53	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

tr|T1ER28|T1ER28_HELRO
Uncharacterized protein
Search

tr|T1ER29|T1ER29_HELRO
Uncharacterized protein
Search

tr|T1ER30|T1ER30_HELRO
Uncharacterized protein
Search

tr|T1ER31|T1ER31_HELRO
Uncharacterized protein
Search

tr|T1ER32|T1ER32_HELRO
Uncharacterized protein
Search

tr|T1ER33|T1ER33_HELRO
Uncharacterized protein
Search

tr|T1ER34|T1ER34_HELRO
Uncharacterized protein
Search

0.53	GO:0030200	heparan sulfate proteoglycan catabolic process
0.52	GO:0033690	positive regulation of osteoblast proliferation
0.51	GO:0060055	angiogenesis involved in wound healing
0.51	GO:0051797	regulation of hair follicle development
0.51	GO:0010575	positive regulation of vascular endothelial growth factor production
0.51	GO:0030194	positive regulation of blood coagulation
0.50	GO:0042635	positive regulation of hair cycle
0.50	GO:0051897	positive regulation of protein kinase B signaling
0.50	GO:0045684	positive regulation of epidermis development
0.49	GO:0007160	cell-matrix adhesion

0.65	GO:0016798	hydrolase activity, acting on glycosyl bonds
0.53	GO:0045545	syndecan binding
0.44	GO:0046983	protein dimerization activity
0.33	GO:0016740	transferase activity
0.33	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.48	GO:0005764	lysosome
0.47	GO:0045121	membrane raft
0.44	GO:0005654	nucleoplasm
0.41	GO:0005578	proteinaceous extracellular matrix
0.38	GO:0098852	lytic vacuole membrane
0.30	GO:0031224	intrinsic component of membrane

0.65

EC:3.2

GO:0016798

tr|T1ER35|T1ER35_HELRO
Uncharacterized protein
Search

tr|T1ER36|T1ER36_HELRO
Uncharacterized protein
Search

0.77	GO:0030133	transport vesicle
0.30	GO:0044425	membrane part

tr|T1ER37|T1ER37_HELRO
Uncharacterized protein
Search

0.70

GO:0005509

calcium ion binding

tr|T1ER38|T1ER38_HELRO
Uncharacterized protein
Search

tr|T1ER39|T1ER39_HELRO
Uncharacterized protein
Search

tr|T1ER40|T1ER40_HELRO
Uncharacterized protein
Search

tr|T1ER41|T1ER41_HELRO
Uncharacterized protein
Search

tr|T1ER42|T1ER42_HELRO
Uncharacterized protein
Search

tr|T1ER43|T1ER43_HELRO
Uncharacterized protein
Search

GLTP

0.45	Glycolipid transfer protein

0.84	GO:0120009	intermembrane lipid transfer
0.54	GO:0035621	ER to Golgi ceramide transport
0.54	GO:0046836	glycolipid transport
0.36	GO:0015031	protein transport
0.34	GO:0006661	phosphatidylinositol biosynthetic process
0.33	GO:0006508	proteolysis

0.85	GO:0120013	intermembrane lipid transfer activity
0.55	GO:0017089	glycolipid transporter activity
0.54	GO:0051861	glycolipid binding
0.53	GO:0097001	ceramide binding
0.50	GO:0070273	phosphatidylinositol-4-phosphate binding
0.37	GO:0042802	identical protein binding
0.33	GO:0008237	metallopeptidase activity
0.33	GO:0003779	actin binding
0.33	GO:0008270	zinc ion binding

0.49	GO:0005802	trans-Golgi network
0.46	GO:0005654	nucleoplasm
0.35	GO:0005829	cytosol
0.34	GO:0000139	Golgi membrane
0.30	GO:0016021	integral component of membrane

tr|T1ER44|T1ER44_HELRO
Uncharacterized protein
Search

tr|T1ER45|T1ER45_HELRO
Uncharacterized protein
Search

tr|T1ER46|T1ER46_HELRO
Uncharacterized protein
Search

0.30

GO:0044425

membrane part

tr|T1ER47|T1ER47_HELRO
Uncharacterized protein
Search

tr|T1ER48|T1ER48_HELRO
Uncharacterized protein
Search

tr|T1ER49|T1ER49_HELRO
Uncharacterized protein
Search

tr|T1ER50|T1ER50_HELRO
Uncharacterized protein
Search

tr|T1ER51|T1ER51_HELRO
Uncharacterized protein
Search

0.71	GO:0010951	negative regulation of endopeptidase activity
0.60	GO:0001558	regulation of cell growth
0.36	GO:0048009	insulin-like growth factor receptor signaling pathway
0.34	GO:0007399	nervous system development

0.74	GO:0004867	serine-type endopeptidase inhibitor activity
0.63	GO:0005520	insulin-like growth factor binding
0.53	GO:0030165	PDZ domain binding
0.36	GO:0005010	insulin-like growth factor-activated receptor activity

0.52	GO:0005576	extracellular region
0.36	GO:0031982	vesicle
0.34	GO:0005581	collagen trimer
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1ER52|T1ER52_HELRO
Uncharacterized protein
Search

tr|T1ER53|T1ER53_HELRO
Uncharacterized protein
Search

0.73	GO:0010951	negative regulation of endopeptidase activity
0.48	GO:0001558	regulation of cell growth
0.44	GO:0030513	positive regulation of BMP signaling pathway
0.44	GO:0002244	hematopoietic progenitor cell differentiation
0.37	GO:0048570	notochord morphogenesis
0.37	GO:0006952	defense response
0.37	GO:0001756	somitogenesis
0.36	GO:0001568	blood vessel development
0.33	GO:0055114	oxidation-reduction process

0.76	GO:0004867	serine-type endopeptidase inhibitor activity
0.50	GO:0005520	insulin-like growth factor binding
0.33	GO:0016491	oxidoreductase activity
0.33	GO:0046872	metal ion binding

0.47	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.33

EC:1

GO:0016491

tr|T1ER54|T1ER54_HELRO
Uncharacterized protein
Search

tr|T1ER55|T1ER55_HELRO
Uncharacterized protein
Search

tr|T1ER56|T1ER56_HELRO
Uncharacterized protein
Search

tr|T1ER57|T1ER57_HELRO
Uncharacterized protein
Search

0.63	GO:0006289	nucleotide-excision repair
0.56	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.53	GO:0016573	histone acetylation
0.50	GO:0016579	protein deubiquitination
0.49	GO:0006511	ubiquitin-dependent protein catabolic process

0.63	GO:0003697	single-stranded DNA binding
0.58	GO:0004519	endonuclease activity
0.54	GO:0004402	histone acetyltransferase activity
0.50	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity

0.54

GO:0005634

nucleus

0.54

EC:2.3.1.48

GO:0004402

tr|T1ER58|T1ER58_HELRO
Uncharacterized protein
Search

0.55	GO:0045332	phospholipid translocation
0.53	GO:0009190	cyclic nucleotide biosynthetic process
0.46	GO:0035556	intracellular signal transduction
0.43	GO:0060255	regulation of macromolecule metabolic process
0.42	GO:0080090	regulation of primary metabolic process
0.42	GO:0031326	regulation of cellular biosynthetic process
0.42	GO:0051171	regulation of nitrogen compound metabolic process
0.38	GO:0036211	protein modification process
0.37	GO:0044267	cellular protein metabolic process
0.37	GO:0016569	covalent chromatin modification

0.55	GO:0004012	phospholipid-translocating ATPase activity
0.52	GO:0016849	phosphorus-oxygen lyase activity
0.47	GO:0000287	magnesium ion binding
0.45	GO:0003723	RNA binding
0.43	GO:0003700	DNA binding transcription factor activity
0.43	GO:0032559	adenyl ribonucleotide binding
0.43	GO:0008144	drug binding
0.43	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0140096	catalytic activity, acting on a protein
0.37	GO:0016278	lysine N-methyltransferase activity

0.38	GO:0005622	intracellular
0.35	GO:0043227	membrane-bounded organelle
0.35	GO:0005887	integral component of plasma membrane
0.34	GO:0043234	protein complex

0.55

EC:3.6.3.1

GO:0004012

tr|T1ER59|T1ER59_HELRO
Uncharacterized protein
Search

0.65

GO:0007160

cell-matrix adhesion

0.30

GO:0031224

intrinsic component of membrane

tr|T1ER60|T1ER60_HELRO
Uncharacterized protein
Search

tr|T1ER61|T1ER61_HELRO
Uncharacterized protein
Search

tr|T1ER62|T1ER62_HELRO
Uncharacterized protein
Search

0.77	GO:0070588	calcium ion transmembrane transport
0.76	GO:0034765	regulation of ion transmembrane transport
0.35	GO:0086010	membrane depolarization during action potential

0.82	GO:0005245	voltage-gated calcium channel activity
0.66	GO:0005509	calcium ion binding

0.81

GO:0005891

voltage-gated calcium channel complex

tr|T1ER63|T1ER63_HELRO
Uncharacterized protein
Search

0.74	Voltage-dependent calcium channel alpha-1 subunit (Fragment)

0.77	GO:0070588	calcium ion transmembrane transport
0.74	GO:0034765	regulation of ion transmembrane transport
0.40	GO:0035545	determination of left/right asymmetry in nervous system
0.40	GO:0086010	membrane depolarization during action potential
0.39	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.39	GO:0007626	locomotory behavior
0.38	GO:0042594	response to starvation
0.38	GO:0009408	response to heat
0.37	GO:0001505	regulation of neurotransmitter levels

0.82	GO:0005245	voltage-gated calcium channel activity
0.66	GO:0005509	calcium ion binding

0.81	GO:0005891	voltage-gated calcium channel complex
0.41	GO:0048787	presynaptic active zone membrane

tr|T1ER64|T1ER64_HELRO
Uncharacterized protein
Search

tr|T1ER65|T1ER65_HELRO
Uncharacterized protein
Search

0.45	GO:0032958	inositol phosphate biosynthetic process
0.41	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.41	GO:0051171	regulation of nitrogen compound metabolic process
0.41	GO:0080090	regulation of primary metabolic process
0.41	GO:0010468	regulation of gene expression
0.38	GO:0016310	phosphorylation
0.36	GO:0097466	ubiquitin-dependent glycoprotein ERAD pathway
0.36	GO:0017182	peptidyl-diphthamide metabolic process
0.36	GO:0019934	cGMP-mediated signaling
0.36	GO:0031152	aggregation involved in sorocarp development

0.42	GO:0003700	DNA binding transcription factor activity
0.39	GO:0003723	RNA binding
0.39	GO:0016301	kinase activity
0.39	GO:0046872	metal ion binding
0.37	GO:0001646	cAMP receptor activity
0.36	GO:0004835	tubulin-tyrosine ligase activity
0.35	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
0.35	GO:0030552	cAMP binding
0.35	GO:0016534	cyclin-dependent protein kinase 5 activator activity
0.35	GO:0017178	diphthine-ammonia ligase activity

0.49	GO:0005680	anaphase-promoting complex
0.39	GO:0036464	cytoplasmic ribonucleoprotein granule
0.36	GO:0030015	CCR4-NOT core complex
0.35	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex
0.35	GO:0020011	apicoplast
0.34	GO:0005783	endoplasmic reticulum
0.34	GO:0005887	integral component of plasma membrane
0.34	GO:0005739	mitochondrion

0.36	EC:6.3.2.25	GO:0004835
0.35	KEGG:R05982 KEGG:R06722	GO:0004571

tr|T1ER66|T1ER66_HELRO
Uncharacterized protein
Search

tr|T1ER67|T1ER67_HELRO
Uncharacterized protein
Search

0.42	GO:1903506	regulation of nucleic acid-templated transcription
0.42	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.42	GO:0010468	regulation of gene expression
0.41	GO:0051276	chromosome organization
0.40	GO:0065009	regulation of molecular function
0.39	GO:0007043	cell-cell junction assembly
0.39	GO:0051716	cellular response to stimulus
0.39	GO:0045132	meiotic chromosome segregation
0.39	GO:0140014	mitotic nuclear division
0.39	GO:0007163	establishment or maintenance of cell polarity

0.44	GO:0003676	nucleic acid binding
0.42	GO:0003700	DNA binding transcription factor activity
0.41	GO:0005509	calcium ion binding
0.41	GO:0008270	zinc ion binding
0.41	GO:0005515	protein binding
0.39	GO:0016307	phosphatidylinositol phosphate kinase activity
0.39	GO:0098772	molecular function regulator
0.38	GO:0032559	adenyl ribonucleotide binding
0.38	GO:0009881	photoreceptor activity
0.38	GO:0008144	drug binding

0.41	GO:0005634	nucleus
0.39	GO:0005694	chromosome
0.36	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.39

GO:0016307

tr|T1ER68|T1ER68_HELRO
Uncharacterized protein
Search

tr|T1ER69|T1ER69_HELRO
Solute carrier organic anion transporter family member
Search

0.33	Solute carrier organic anion transporter family member

0.57	GO:0006811	ion transport
0.55	GO:0055085	transmembrane transport
0.47	GO:1901571	fatty acid derivative transport
0.45	GO:0006869	lipid transport
0.43	GO:0015849	organic acid transport
0.41	GO:1905431	microcystin transport
0.35	GO:0015850	organic hydroxy compound transport
0.34	GO:0070327	thyroid hormone transport
0.33	GO:0001889	liver development
0.33	GO:0006402	mRNA catabolic process

0.56	GO:0005215	transporter activity
0.34	GO:0004654	polyribonucleotide nucleotidyltransferase activity
0.33	GO:0030246	carbohydrate binding
0.32	GO:0003723	RNA binding
0.32	GO:0008233	peptidase activity

0.54	GO:0005886	plasma membrane
0.35	GO:0043229	intracellular organelle
0.33	GO:0045177	apical part of cell
0.30	GO:0016021	integral component of membrane

0.34

EC:2.7.7.8

GO:0004654

tr|T1ER70|T1ER70_HELRO
Uncharacterized protein
Search

tr|T1ER71|T1ER71_HELRO
Uncharacterized protein
Search

tr|T1ER72|T1ER72_HELRO
Uncharacterized protein
Search

tr|T1ER73|T1ER73_HELRO
Uncharacterized protein
Search

0.44	Tigger transposable element-derived protein 6-like protein (Fragment)

0.55

GO:0003677

DNA binding

tr|T1ER74|T1ER74_HELRO
Uncharacterized protein
Search

tr|T1ER75|T1ER75_HELRO
Uncharacterized protein
Search

tr|T1ER76|T1ER76_HELRO
Uncharacterized protein
Search

tr|T1ER77|T1ER77_HELRO
Uncharacterized protein
Search

tr|T1ER78|T1ER78_HELRO
Uncharacterized protein
Search

tr|T1ER79|T1ER79_HELRO
Uncharacterized protein
Search

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.47	GO:0007166	cell surface receptor signaling pathway
0.47	GO:0007186	G-protein coupled receptor signaling pathway
0.45	GO:0044331	cell-cell adhesion mediated by cadherin
0.45	GO:0045317	equator specification
0.45	GO:0090176	microtubule cytoskeleton organization involved in establishment of planar polarity
0.44	GO:0001737	establishment of imaginal disc-derived wing hair orientation
0.44	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.44	GO:0090175	regulation of establishment of planar polarity
0.44	GO:0035159	regulation of tube length, open tracheal system

0.70	GO:0005509	calcium ion binding
0.47	GO:0004930	G-protein coupled receptor activity
0.42	GO:0045296	cadherin binding
0.36	GO:0005044	scavenger receptor activity

0.56	GO:0005886	plasma membrane
0.36	GO:0032420	stereocilium
0.30	GO:0031224	intrinsic component of membrane

tr|T1ER80|T1ER80_HELRO
Uncharacterized protein
Search

tr|T1ER81|T1ER81_HELRO
Uncharacterized protein
Search

tr|T1ER82|T1ER82_HELRO
Uncharacterized protein
Search

tr|T1ER83|T1ER83_HELRO
Uncharacterized protein
Search

tr|T1ER84|T1ER84_HELRO
Uncharacterized protein
Search

tr|T1ER85|T1ER85_HELRO
Uncharacterized protein
Search

0.74

GO:0010469

regulation of receptor activity

0.76	GO:0008083	growth factor activity
0.36	GO:0003676	nucleic acid binding

tr|T1ER86|T1ER86_HELRO
Uncharacterized protein
Search

tr|T1ER87|T1ER87_HELRO
Uncharacterized protein
Search

0.68	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7

0.69

GO:0042773

ATP synthesis coupled electron transport

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane

0.69

EC:1.6.5.3

GO:0008137

tr|T1ER88|T1ER88_HELRO
Uncharacterized protein
Search

tr|T1ER89|T1ER89_HELRO
Uncharacterized protein
Search

tr|T1ER90|T1ER90_HELRO
Uncharacterized protein
Search

tr|T1ER91|T1ER91_HELRO
Uncharacterized protein
Search

tr|T1ER92|T1ER92_HELRO
Uncharacterized protein
Search

0.79	GO:0045010	actin nucleation
0.63	GO:0007316	pole plasm RNA localization
0.38	GO:0060811	intracellular mRNA localization involved in anterior/posterior axis specification
0.38	GO:0007304	chorion-containing eggshell formation
0.35	GO:0015031	protein transport

0.73	GO:0008017	microtubule binding
0.36	GO:0003779	actin binding

0.81	GO:0005884	actin filament
0.55	GO:0005938	cell cortex
0.36	GO:0030659	cytoplasmic vesicle membrane
0.35	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

tr|T1ER93|T1ER93_HELRO
Uncharacterized protein
Search

tr|T1ER94|T1ER94_HELRO
Uncharacterized protein
Search

0.41	Transcription elongation factor spt6

0.75	GO:0032784	regulation of DNA-templated transcription, elongation
0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.60	GO:0006414	translational elongation
0.54	GO:0006351	transcription, DNA-templated
0.47	GO:0061086	negative regulation of histone H3-K27 methylation
0.46	GO:0070827	chromatin maintenance
0.45	GO:0071599	otic vesicle development
0.45	GO:0001756	somitogenesis
0.44	GO:0035050	embryonic heart tube development
0.44	GO:0006342	chromatin silencing

0.85	GO:0000991	transcription factor activity, core RNA polymerase II binding
0.61	GO:0003746	translation elongation factor activity
0.51	GO:0003677	DNA binding
0.44	GO:0031491	nucleosome binding
0.44	GO:0042393	histone binding
0.38	GO:0003700	DNA binding transcription factor activity

0.57	GO:0005634	nucleus
0.45	GO:0035327	transcriptionally active chromatin
0.40	GO:0031974	membrane-enclosed lumen
0.38	GO:0043234	protein complex

tr|T1ER95|T1ER95_HELRO
Uncharacterized protein
Search

tr|T1ER96|T1ER96_HELRO
Uncharacterized protein
Search

0.76	GO:0007093	mitotic cell cycle checkpoint
0.75	GO:0051304	chromosome separation
0.63	GO:0006468	protein phosphorylation
0.56	GO:1903096	protein localization to meiotic spindle midzone
0.54	GO:0016321	female meiosis chromosome segregation
0.54	GO:0044779	meiotic spindle checkpoint
0.52	GO:0034501	protein localization to kinetochore
0.52	GO:0018210	peptidyl-threonine modification
0.51	GO:0071173	spindle assembly checkpoint
0.51	GO:0018209	peptidyl-serine modification

0.77	GO:0004712	protein serine/threonine/tyrosine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0042803	protein homodimerization activity
0.47	GO:0004674	protein serine/threonine kinase activity
0.37	GO:0043515	kinetochore binding
0.37	GO:0004713	protein tyrosine kinase activity
0.33	GO:0003735	structural constituent of ribosome
0.33	GO:0003677	DNA binding

0.49	GO:0000776	kinetochore
0.38	GO:0005737	cytoplasm
0.34	GO:0015630	microtubule cytoskeleton
0.34	GO:0044430	cytoskeletal part
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.77

EC:2.7.12.1

GO:0004712

tr|T1ER97|T1ER97_HELRO
Uncharacterized protein
Search

tr|T1ER98|T1ER98_HELRO
Uncharacterized protein
Search

tr|T1ER99|T1ER99_HELRO
Uncharacterized protein
Search

0.62	GO:0000226	microtubule cytoskeleton organization
0.43	GO:0006233	dTDP biosynthetic process
0.41	GO:0006235	dTTP biosynthetic process
0.40	GO:0046939	nucleotide phosphorylation
0.38	GO:0006413	translational initiation
0.37	GO:0040035	hermaphrodite genitalia development
0.37	GO:0040025	vulval development
0.37	GO:0006886	intracellular protein transport
0.37	GO:0071470	cellular response to osmotic stress
0.37	GO:0006487	protein N-linked glycosylation

0.43	GO:0004798	thymidylate kinase activity
0.42	GO:0003924	GTPase activity
0.41	GO:0005525	GTP binding
0.38	GO:0030554	adenyl nucleotide binding
0.38	GO:0008092	cytoskeletal protein binding
0.38	GO:0003743	translation initiation factor activity
0.38	GO:0008144	drug binding
0.38	GO:0003682	chromatin binding
0.37	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.37	GO:0032403	protein complex binding

0.58	GO:0015630	microtubule cytoskeleton
0.37	GO:0019867	outer membrane
0.36	GO:0005634	nucleus
0.35	GO:0043234	protein complex
0.35	GO:0016282	eukaryotic 43S preinitiation complex
0.35	GO:0044430	cytoskeletal part
0.35	GO:0033290	eukaryotic 48S preinitiation complex
0.34	GO:0031226	intrinsic component of plasma membrane
0.34	GO:0015629	actin cytoskeleton
0.34	GO:0012505	endomembrane system

0.43

EC:2.7.4.9

GO:0004798

tr|T1ERA0|T1ERA0_HELRO
Uncharacterized protein
Search

tr|T1ERA1|T1ERA1_HELRO
Uncharacterized protein
Search

0.50

GO:0006030

chitin metabolic process

0.49	GO:0008061	chitin binding
0.40	GO:0003723	RNA binding

0.58	GO:0070701	mucus layer
0.30	GO:0031224	intrinsic component of membrane

tr|T1ERA2|T1ERA2_HELRO
Uncharacterized protein
Search

tr|T1ERA3|T1ERA3_HELRO
Uncharacterized protein
Search

tr|T1ERA4|T1ERA4_HELRO
Uncharacterized protein
Search

0.78	GO:0080009	mRNA methylation
0.48	GO:0007539	primary sex determination, soma
0.45	GO:0007298	border follicle cell migration
0.45	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.42	GO:0010951	negative regulation of endopeptidase activity
0.42	GO:0000375	RNA splicing, via transesterification reactions

0.43

GO:0004866

endopeptidase inhibitor activity

0.85	GO:0036396	RNA N6-methyladenosine methyltransferase complex
0.77	GO:0016607	nuclear speck
0.66	GO:0005829	cytosol
0.42	GO:0005615	extracellular space

tr|T1ERA5|T1ERA5_HELRO
Uncharacterized protein
Search

tr|T1ERA6|T1ERA6_HELRO
Uncharacterized protein
Search

0.68

GO:0046983

protein dimerization activity

tr|T1ERA7|T1ERA7_HELRO
Uncharacterized protein
Search

tr|T1ERA8|T1ERA8_HELRO
Uncharacterized protein
Search

tr|T1ERA9|T1ERA9_HELRO
Uncharacterized protein
Search

0.57	zinc finger protein 395

0.40	GO:0008643	carbohydrate transport
0.37	GO:0006357	regulation of transcription by RNA polymerase II

0.51

GO:0003676

nucleic acid binding

0.36	GO:0005634	nucleus
0.30	GO:0044425	membrane part

tr|T1ERB0|T1ERB0_HELRO
Uncharacterized protein
Search

KDM8

0.88	Lysine-specific demethylase

0.57	GO:0032259	methylation
0.56	GO:0070544	histone H3-K36 demethylation
0.54	GO:0000086	G2/M transition of mitotic cell cycle
0.49	GO:0045893	positive regulation of transcription, DNA-templated
0.44	GO:0006357	regulation of transcription by RNA polymerase II
0.36	GO:0006367	transcription initiation from RNA polymerase II promoter
0.34	GO:0006508	proteolysis
0.34	GO:0055114	oxidation-reduction process
0.34	GO:0000413	protein peptidyl-prolyl isomerization

0.57	GO:0008168	methyltransferase activity
0.56	GO:0051864	histone demethylase activity (H3-K36 specific)
0.50	GO:0003682	chromatin binding
0.47	GO:0001104	RNA polymerase II transcription cofactor activity
0.36	GO:0004597	peptide-aspartate beta-dioxygenase activity
0.36	GO:0008080	N-acetyltransferase activity
0.35	GO:0008233	peptidase activity
0.34	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.34	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.58	GO:0048786	presynaptic active zone
0.53	GO:0005654	nucleoplasm
0.47	GO:0005829	cytosol
0.41	GO:0043234	protein complex
0.36	GO:0055029	nuclear DNA-directed RNA polymerase complex
0.35	GO:0005694	chromosome
0.30	GO:0031224	intrinsic component of membrane

0.57

GO:0008168

tr|T1ERB1|T1ERB1_HELRO
Uncharacterized protein
Search

tr|T1ERB2|T1ERB2_HELRO
Uncharacterized protein
Search

tr|T1ERB3|T1ERB3_HELRO
Uncharacterized protein
Search

tr|T1ERB4|T1ERB4_HELRO
Uncharacterized protein
Search

tr|T1ERB5|T1ERB5_HELRO
Uncharacterized protein
Search

tr|T1ERB6|T1ERB6_HELRO
Uncharacterized protein
Search

0.93	RLL motif containing protein 1

tr|T1ERB7|T1ERB7_HELRO
Uncharacterized protein
Search

tr|T1ERB8|T1ERB8_HELRO
Uncharacterized protein
Search

tr|T1ERB9|T1ERB9_HELRO
Uncharacterized protein
Search

0.55	GO:0006811	ion transport
0.54	GO:0055085	transmembrane transport
0.41	GO:0071702	organic substance transport
0.41	GO:0070327	thyroid hormone transport
0.36	GO:0007588	excretion
0.36	GO:0010876	lipid localization

0.56	GO:0005215	transporter activity
0.33	GO:0008270	zinc ion binding

0.52	GO:0005886	plasma membrane
0.33	GO:0043229	intracellular organelle
0.30	GO:0016021	integral component of membrane

tr|T1ERC0|T1ERC0_HELRO
Uncharacterized protein
Search

tr|T1ERC1|T1ERC1_HELRO
Uncharacterized protein
Search

tr|T1ERC2|T1ERC2_HELRO
Uncharacterized protein
Search

tr|T1ERC3|T1ERC3_HELRO
Uncharacterized protein
Search

tr|T1ERC4|T1ERC4_HELRO
Uncharacterized protein
Search

tr|T1ERC5|T1ERC5_HELRO
Uncharacterized protein
Search

0.55	GO:0055085	transmembrane transport
0.55	GO:0006811	ion transport
0.44	GO:0071702	organic substance transport
0.41	GO:0010876	lipid localization
0.40	GO:1901998	toxin transport
0.38	GO:0070327	thyroid hormone transport
0.37	GO:0042886	amide transport

0.56

GO:0005215

transporter activity

0.52	GO:0005886	plasma membrane
0.36	GO:0043229	intracellular organelle
0.30	GO:0016021	integral component of membrane

tr|T1ERC6|T1ERC6_HELRO
Uncharacterized protein
Search

0.50	Glycerol-3-phosphate dehydrogenase, mitochondrial

0.76	GO:0006072	glycerol-3-phosphate metabolic process
0.53	GO:0055114	oxidation-reduction process
0.42	GO:0035264	multicellular organism growth
0.41	GO:0043010	camera-type eye development
0.39	GO:0006094	gluconeogenesis
0.37	GO:0006734	NADH metabolic process
0.36	GO:0007629	flight behavior
0.35	GO:0019563	glycerol catabolic process
0.34	GO:0042180	cellular ketone metabolic process
0.33	GO:0006091	generation of precursor metabolites and energy

0.79	GO:0004368	glycerol-3-phosphate dehydrogenase activity
0.69	GO:0005509	calcium ion binding
0.34	GO:0008536	Ran GTPase binding
0.34	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity
0.33	GO:0043565	sequence-specific DNA binding
0.33	GO:0008270	zinc ion binding
0.33	GO:0003700	DNA binding transcription factor activity

0.76	GO:0009331	glycerol-3-phosphate dehydrogenase complex
0.38	GO:0031966	mitochondrial membrane
0.38	GO:0019866	organelle inner membrane
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.79	EC:1.1.5.3	GO:0004368
0.34	KEGG:R00842	GO:0004367

tr|T1ERC7|T1ERC7_HELRO
Glycerol-3-phosphate dehydrogenase
Search

0.29	Glycerol-3-phosphate dehydrogenase

0.76	GO:0006072	glycerol-3-phosphate metabolic process
0.53	GO:0055114	oxidation-reduction process
0.48	GO:0035264	multicellular organism growth
0.47	GO:0043010	camera-type eye development
0.44	GO:0019319	hexose biosynthetic process
0.44	GO:0006006	glucose metabolic process
0.39	GO:0019563	glycerol catabolic process
0.37	GO:0006734	NADH metabolic process
0.34	GO:0007629	flight behavior
0.34	GO:0042180	cellular ketone metabolic process

0.79	GO:0004368	glycerol-3-phosphate dehydrogenase activity
0.66	GO:0005509	calcium ion binding
0.34	GO:0008536	Ran GTPase binding
0.34	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity
0.33	GO:0043565	sequence-specific DNA binding
0.33	GO:0008270	zinc ion binding
0.33	GO:0003700	DNA binding transcription factor activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.76	GO:0009331	glycerol-3-phosphate dehydrogenase complex
0.41	GO:0031966	mitochondrial membrane
0.41	GO:0019866	organelle inner membrane
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.79	EC:1.1.5.3	GO:0004368
0.34	KEGG:R00842	GO:0004367

tr|T1ERC8|T1ERC8_HELRO
Uncharacterized protein
Search

tr|T1ERC9|T1ERC9_HELRO
Uncharacterized protein
Search

0.52	GO:0032259	methylation
0.44	GO:0070868	heterochromatin organization involved in chromatin silencing
0.43	GO:0035065	regulation of histone acetylation
0.34	GO:0016570	histone modification
0.34	GO:0018205	peptidyl-lysine modification
0.34	GO:0008213	protein alkylation
0.34	GO:0045010	actin nucleation
0.33	GO:0097190	apoptotic signaling pathway

0.53	GO:0046872	metal ion binding
0.53	GO:0008168	methyltransferase activity
0.43	GO:0035064	methylated histone binding
0.41	GO:0003682	chromatin binding
0.34	GO:0008017	microtubule binding
0.34	GO:0140096	catalytic activity, acting on a protein
0.32	GO:0046982	protein heterodimerization activity
0.32	GO:0003676	nucleic acid binding

0.43	GO:0035327	transcriptionally active chromatin
0.43	GO:0005700	polytene chromosome
0.38	GO:0005634	nucleus
0.34	GO:0005884	actin filament
0.30	GO:0031224	intrinsic component of membrane

0.53

GO:0008168

tr|T1ERD0|T1ERD0_HELRO
Uncharacterized protein
Search

0.86

GO:0043984

histone H4-K16 acetylation

0.85	GO:0072487	MSL complex
0.30	GO:0031224	intrinsic component of membrane

tr|T1ERD1|T1ERD1_HELRO
Uncharacterized protein
Search

RAB18

0.93	RAB18, member RAS oncogene family

0.61	GO:0034389	lipid particle organization
0.58	GO:0071786	endoplasmic reticulum tubular network organization
0.46	GO:0051170	nuclear import
0.39	GO:0001654	eye development
0.39	GO:0043009	chordate embryonic development
0.37	GO:0007420	brain development

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032553	ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.56	GO:0071782	endoplasmic reticulum tubular network
0.46	GO:0005794	Golgi apparatus

tr|T1ERD2|T1ERD2_HELRO
Uncharacterized protein
Search

POLL

0.43	DNA nucleotidylexotransferase

0.67	GO:0071897	DNA biosynthetic process
0.65	GO:0006281	DNA repair
0.40	GO:0006310	DNA recombination
0.35	GO:0006260	DNA replication
0.34	GO:0016446	somatic hypermutation of immunoglobulin genes
0.33	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.33	GO:1903047	mitotic cell cycle process
0.32	GO:0006508	proteolysis
0.32	GO:0032774	RNA biosynthetic process

0.71	GO:0003887	DNA-directed DNA polymerase activity
0.55	GO:0003677	DNA binding
0.49	GO:0051575	5'-deoxyribose-5-phosphate lyase activity
0.41	GO:0046872	metal ion binding
0.35	GO:0016787	hydrolase activity
0.34	GO:0003912	DNA nucleotidylexotransferase activity
0.33	GO:0003896	DNA primase activity
0.32	GO:0005515	protein binding
0.32	GO:0008080	N-acetyltransferase activity
0.32	GO:0140096	catalytic activity, acting on a protein

0.60	GO:0005634	nucleus
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0044446	intracellular organelle part
0.32	GO:0042025	host cell nucleus
0.30	GO:0031224	intrinsic component of membrane

0.71

EC:2.7.7.7

GO:0003887

tr|T1ERD3|T1ERD3_HELRO
Uncharacterized protein
Search

tr|T1ERD4|T1ERD4_HELRO
Uncharacterized protein
Search

0.12	Protein import into mitochondrial inner membrane

0.86

GO:0055120

striated muscle dense body

tr|T1ERD5|T1ERD5_HELRO
Uncharacterized protein
Search

tr|T1ERD6|T1ERD6_HELRO
Uncharacterized protein
Search

tr|T1ERD7|T1ERD7_HELRO
Uncharacterized protein
Search

tr|T1ERD8|T1ERD8_HELRO
Uncharacterized protein
Search

tr|T1ERD9|T1ERD9_HELRO
Uncharacterized protein
Search

DBNL

0.93	Drebrin-like protein-like

0.80	GO:0097178	ruffle assembly
0.77	GO:0007416	synapse assembly
0.72	GO:0048812	neuron projection morphogenesis
0.66	GO:0006898	receptor-mediated endocytosis
0.38	GO:0071800	podosome assembly
0.38	GO:0016601	Rac protein signal transduction
0.35	GO:0072553	terminal button organization
0.35	GO:0045887	positive regulation of synaptic growth at neuromuscular junction
0.35	GO:0022416	chaeta development

0.74	GO:0003779	actin binding
0.68	GO:0032403	protein complex binding
0.38	GO:0045296	cadherin binding
0.36	GO:0019904	protein domain specific binding
0.35	GO:0001786	phosphatidylserine binding
0.35	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.35	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding

0.45	GO:0005622	intracellular
0.39	GO:0001726	ruffle
0.39	GO:0030027	lamellipodium
0.36	GO:0045202	synapse
0.36	GO:0043228	non-membrane-bounded organelle
0.35	GO:0044422	organelle part
0.35	GO:0043234	protein complex
0.35	GO:0071944	cell periphery
0.35	GO:0030054	cell junction
0.35	GO:0030426	growth cone

tr|T1ERE0|T1ERE0_HELRO
Uncharacterized protein
Search

tr|T1ERE1|T1ERE1_HELRO
Uncharacterized protein
Search

0.86	Transcription factor SPT20 homolog (Fragment)

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.49	GO:0045722	positive regulation of gluconeogenesis
0.44	GO:1902680	positive regulation of RNA biosynthetic process
0.44	GO:0010628	positive regulation of gene expression
0.39	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.38	GO:0007369	gastrulation
0.34	GO:0006914	autophagy

0.76	GO:0003712	transcription cofactor activity
0.33	GO:0005515	protein binding
0.32	GO:0070403	NAD+ binding

0.80	GO:0000124	SAGA complex
0.51	GO:0001650	fibrillar center

tr|T1ERE2|T1ERE2_HELRO
Uncharacterized protein
Search

0.45	GO:2001141	regulation of RNA biosynthetic process
0.42	GO:0036211	protein modification process
0.42	GO:0044267	cellular protein metabolic process
0.40	GO:0008285	negative regulation of cell proliferation
0.40	GO:0016310	phosphorylation
0.39	GO:0043632	modification-dependent macromolecule catabolic process
0.39	GO:0006996	organelle organization
0.39	GO:0030163	protein catabolic process
0.38	GO:0051641	cellular localization
0.38	GO:0033036	macromolecule localization

0.54	GO:0003712	transcription cofactor activity
0.43	GO:0008270	zinc ion binding
0.42	GO:0140096	catalytic activity, acting on a protein
0.41	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.40	GO:0016301	kinase activity
0.40	GO:0003677	DNA binding
0.40	GO:0030554	adenyl nucleotide binding
0.39	GO:0097367	carbohydrate derivative binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0008144	drug binding

0.56	GO:0000124	SAGA complex
0.37	GO:0044444	cytoplasmic part
0.37	GO:0048475	coated membrane
0.36	GO:0034399	nuclear periphery
0.36	GO:0012506	vesicle membrane
0.35	GO:0017053	transcriptional repressor complex
0.35	GO:0097708	intracellular vesicle
0.35	GO:0098805	whole membrane
0.35	GO:0016459	myosin complex
0.35	GO:0098588	bounding membrane of organelle

0.41

GO:0016773

tr|T1ERE3|T1ERE3_HELRO
Uncharacterized protein
Search

0.44	GO:0007624	ultradian rhythm
0.44	GO:0043044	ATP-dependent chromatin remodeling
0.44	GO:0010512	negative regulation of phosphatidylinositol biosynthetic process
0.43	GO:0043547	positive regulation of GTPase activity
0.42	GO:0045893	positive regulation of transcription, DNA-templated
0.42	GO:0006897	endocytosis
0.41	GO:0048268	clathrin coat assembly
0.41	GO:0036211	protein modification process
0.41	GO:0006357	regulation of transcription by RNA polymerase II
0.40	GO:0044267	cellular protein metabolic process

0.43	GO:0005515	protein binding
0.43	GO:0005096	GTPase activator activity
0.42	GO:0140110	transcription regulator activity
0.42	GO:0050825	ice binding
0.41	GO:0005545	1-phosphatidylinositol binding
0.41	GO:0140096	catalytic activity, acting on a protein
0.40	GO:0030554	adenyl nucleotide binding
0.40	GO:0016301	kinase activity
0.40	GO:0097367	carbohydrate derivative binding
0.40	GO:0008144	drug binding

0.44	GO:0005634	nucleus
0.42	GO:0030479	actin cortical patch
0.40	GO:0030136	clathrin-coated vesicle
0.39	GO:0070013	intracellular organelle lumen
0.38	GO:0044427	chromosomal part
0.37	GO:0032040	small-subunit processome
0.36	GO:1904949	ATPase complex
0.36	GO:0000793	condensed chromosome
0.35	GO:0033202	DNA helicase complex
0.34	GO:0005886	plasma membrane

0.38

GO:0016773

tr|T1ERE4|T1ERE4_HELRO
Uncharacterized protein
Search

0.11	Pogo transposable element with KRAB (Fragment)

0.54

GO:0003677

DNA binding

tr|T1ERE5|T1ERE5_HELRO
Uncharacterized protein
Search

tr|T1ERE6|T1ERE6_HELRO
Uncharacterized protein
Search

0.45	GO:0065007	biological regulation
0.44	GO:0046854	phosphatidylinositol phosphorylation
0.42	GO:0006351	transcription, DNA-templated
0.42	GO:0051716	cellular response to stimulus
0.42	GO:0023052	signaling
0.42	GO:0007154	cell communication
0.41	GO:0006996	organelle organization
0.40	GO:0043412	macromolecule modification
0.40	GO:0007017	microtubule-based process
0.39	GO:0019538	protein metabolic process

0.44	GO:0140110	transcription regulator activity
0.43	GO:0003676	nucleic acid binding
0.41	GO:0016301	kinase activity
0.40	GO:0140096	catalytic activity, acting on a protein
0.40	GO:0008270	zinc ion binding
0.39	GO:0005200	structural constituent of cytoskeleton
0.38	GO:0032555	purine ribonucleotide binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0019899	enzyme binding
0.38	GO:0001099	basal RNA polymerase II transcription machinery binding

0.47	GO:0005634	nucleus
0.44	GO:0031974	membrane-enclosed lumen
0.42	GO:0044446	intracellular organelle part
0.41	GO:0005856	cytoskeleton
0.40	GO:0032991	macromolecular complex
0.38	GO:0099512	supramolecular fiber
0.37	GO:0005694	chromosome
0.36	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.38

EC:2.3.1

GO:0016407

tr|T1ERE7|T1ERE7_HELRO
Uncharacterized protein
Search

tr|T1ERE8|T1ERE8_HELRO
Uncharacterized protein
Search

0.63	GO:0007186	G-protein coupled receptor signaling pathway
0.38	GO:1903665	negative regulation of asexual reproduction
0.36	GO:2001141	regulation of RNA biosynthetic process
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:0010468	regulation of gene expression
0.35	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.35	GO:0055085	transmembrane transport
0.34	GO:0007602	phototransduction
0.34	GO:0007601	visual perception
0.34	GO:0018298	protein-chromophore linkage

0.64	GO:0004930	G-protein coupled receptor activity
0.40	GO:0046872	metal ion binding
0.37	GO:0003700	DNA binding transcription factor activity
0.35	GO:0003677	DNA binding
0.35	GO:0001653	peptide receptor activity
0.35	GO:0004518	nuclease activity
0.35	GO:0022857	transmembrane transporter activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0043492	ATPase activity, coupled to movement of substances
0.34	GO:0008144	drug binding

0.35	GO:0031410	cytoplasmic vesicle
0.35	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:3.1

GO:0004518

tr|T1ERE9|T1ERE9_HELRO
Uncharacterized protein
Search

0.43	GO:0008643	carbohydrate transport
0.40	GO:0006468	protein phosphorylation
0.39	GO:0007275	multicellular organism development
0.39	GO:0055085	transmembrane transport
0.38	GO:0006413	translational initiation
0.36	GO:0006351	transcription, DNA-templated
0.36	GO:0015031	protein transport
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:0010468	regulation of gene expression

0.40	GO:0004672	protein kinase activity
0.39	GO:0046872	metal ion binding
0.39	GO:0003676	nucleic acid binding
0.38	GO:0032555	purine ribonucleotide binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0003924	GTPase activity
0.37	GO:0030554	adenyl nucleotide binding
0.37	GO:0032550	purine ribonucleoside binding
0.37	GO:0019001	guanyl nucleotide binding
0.37	GO:0008144	drug binding

0.59	GO:0048188	Set1C/COMPASS complex
0.38	GO:0005615	extracellular space
0.37	GO:0005794	Golgi apparatus
0.30	GO:0016020	membrane

0.35

EC:1

GO:0016491

tr|T1ERF0|T1ERF0_HELRO
Uncharacterized protein
Search

tr|T1ERF1|T1ERF1_HELRO
Uncharacterized protein
Search

tr|T1ERF2|T1ERF2_HELRO
Uncharacterized protein
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tr|T1ERF3|T1ERF3_HELRO
Uncharacterized protein
Search

0.44	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.43	GO:0051028	mRNA transport
0.42	GO:0000398	mRNA splicing, via spliceosome
0.42	GO:0006405	RNA export from nucleus
0.37	GO:0009298	GDP-mannose biosynthetic process
0.36	GO:0015992	proton transport
0.36	GO:0046034	ATP metabolic process
0.35	GO:0005975	carbohydrate metabolic process

0.37	GO:0004476	mannose-6-phosphate isomerase activity
0.37	GO:0005515	protein binding
0.36	GO:0003723	RNA binding
0.35	GO:0008270	zinc ion binding
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005634	nucleus
0.45	GO:0044446	intracellular organelle part
0.45	GO:0030529	intracellular ribonucleoprotein complex
0.38	GO:0043234	protein complex

0.37

EC:5.3.1.8

GO:0004476

tr|T1ERF4|T1ERF4_HELRO
Uncharacterized protein
Search

tr|T1ERF5|T1ERF5_HELRO
Uncharacterized protein
Search

tr|T1ERF6|T1ERF6_HELRO
Uncharacterized protein
Search

tr|T1ERF7|T1ERF7_HELRO
Uncharacterized protein
Search

tr|T1ERF8|T1ERF8_HELRO
Uncharacterized protein
Search

0.40	Fumarate hydratase class II

0.78	GO:0006106	fumarate metabolic process
0.70	GO:0006099	tricarboxylic acid cycle
0.39	GO:0006108	malate metabolic process
0.35	GO:0048873	homeostasis of number of cells within a tissue
0.34	GO:0006525	arginine metabolic process
0.34	GO:0022900	electron transport chain
0.34	GO:0007034	vacuolar transport

0.79	GO:0004333	fumarate hydratase activity
0.36	GO:0008177	succinate dehydrogenase (ubiquinone) activity
0.36	GO:0004053	arginase activity
0.35	GO:0050660	flavin adenine dinucleotide binding
0.33	GO:0051087	chaperone binding
0.33	GO:0046872	metal ion binding
0.32	GO:0003677	DNA binding

0.77	GO:0045239	tricarboxylic acid cycle enzyme complex
0.41	GO:0005759	mitochondrial matrix
0.39	GO:0005829	cytosol
0.34	GO:0031966	mitochondrial membrane
0.34	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.79	EC:4.2.1.2	GO:0004333
0.79	KEGG:R01082	GO:0004333

tr|T1ERF9|T1ERF9_HELRO
Uncharacterized protein
Search

0.70	Etoposide-induced protein 2.4

0.41	GO:0016236	macroautophagy
0.40	GO:0006915	apoptotic process
0.39	GO:1901418	positive regulation of response to ethanol
0.36	GO:1902902	negative regulation of autophagosome assembly
0.33	GO:0006468	protein phosphorylation

0.34	GO:0004672	protein kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.39	GO:0005783	endoplasmic reticulum
0.30	GO:0016020	membrane

tr|T1ERG0|T1ERG0_HELRO
Uncharacterized protein
Search

0.77	GO:0045329	carnitine biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.37	GO:0043547	positive regulation of GTPase activity

0.71	GO:0008336	gamma-butyrobetaine dioxygenase activity
0.57	GO:0005506	iron ion binding
0.56	GO:0050353	trimethyllysine dioxygenase activity
0.48	GO:0042802	identical protein binding
0.44	GO:0008270	zinc ion binding
0.37	GO:0005096	GTPase activator activity
0.34	GO:0003677	DNA binding

0.43	GO:0005739	mitochondrion
0.36	GO:0070062	extracellular exosome
0.34	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.71	EC:1.14.11.1	GO:0008336
0.71	KEGG:R02397	GO:0008336

tr|T1ERG1|T1ERG1_HELRO
Uncharacterized protein
Search

0.61	GO:0032186	cellular bud neck septin ring organization
0.60	GO:0097271	protein localization to bud neck
0.60	GO:0031578	mitotic spindle orientation checkpoint
0.60	GO:0090337	regulation of formin-nucleated actin cable assembly
0.58	GO:0000132	establishment of mitotic spindle orientation
0.58	GO:0051865	protein autoubiquitination
0.58	GO:0000921	septin ring assembly
0.56	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process

0.52	GO:0004842	ubiquitin-protein transferase activity
0.41	GO:0016874	ligase activity
0.40	GO:0046872	metal ion binding

0.63	GO:0032176	split septin rings
0.59	GO:0000399	cellular bud neck septin structure
0.59	GO:0032161	cleavage apparatus septin structure
0.57	GO:0005934	cellular bud tip
0.30	GO:0016020	membrane

0.41	EC:6	GO:0016874
0.52	KEGG:R03876	GO:0004842

tr|T1ERG2|T1ERG2_HELRO
Uncharacterized protein
Search

tr|T1ERG3|T1ERG3_HELRO
Uncharacterized protein
Search

0.79	GO:0007411	axon guidance
0.38	GO:0048730	epidermis morphogenesis
0.38	GO:0002119	nematode larval development
0.38	GO:0016477	cell migration
0.37	GO:0042060	wound healing
0.37	GO:0009792	embryo development ending in birth or egg hatching
0.35	GO:0045887	positive regulation of synaptic growth at neuromuscular junction
0.35	GO:0097009	energy homeostasis
0.35	GO:0050908	detection of light stimulus involved in visual perception
0.35	GO:2000637	positive regulation of gene silencing by miRNA

0.34	GO:0005057	signal transducer activity, downstream of receptor
0.33	GO:0005515	protein binding
0.32	GO:0046872	metal ion binding
0.30	GO:0003824	catalytic activity

0.40	GO:0009986	cell surface
0.35	GO:0098595	perivitelline space
0.35	GO:0031594	neuromuscular junction
0.34	GO:0005925	focal adhesion
0.32	GO:0005886	plasma membrane
0.32	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

tr|T1ERG4|T1ERG4_HELRO
Uncharacterized protein
Search

0.59	GO:0048106	establishment of thoracic bristle planar orientation
0.58	GO:0035321	maintenance of imaginal disc-derived wing hair orientation
0.58	GO:0007403	glial cell fate determination
0.56	GO:0007400	neuroblast fate determination
0.56	GO:0008586	imaginal disc-derived wing vein morphogenesis
0.55	GO:0007379	segment specification
0.55	GO:0035222	wing disc pattern formation
0.54	GO:0007173	epidermal growth factor receptor signaling pathway
0.54	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.54	GO:0007422	peripheral nervous system development

0.53	GO:0003723	RNA binding
0.44	GO:0050825	ice binding
0.41	GO:0035800	deubiquitinase activator activity
0.38	GO:0003682	chromatin binding
0.38	GO:0004386	helicase activity
0.38	GO:0097367	carbohydrate derivative binding
0.38	GO:0008144	drug binding
0.37	GO:0030554	adenyl nucleotide binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0005249	voltage-gated potassium channel activity

0.49	GO:0005634	nucleus
0.45	GO:0000428	DNA-directed RNA polymerase complex
0.45	GO:0005667	transcription factor complex
0.42	GO:0070013	intracellular organelle lumen
0.41	GO:0044446	intracellular organelle part
0.37	GO:0008076	voltage-gated potassium channel complex
0.37	GO:0005694	chromosome
0.36	GO:0005794	Golgi apparatus
0.36	GO:0098588	bounding membrane of organelle
0.35	GO:0005576	extracellular region

tr|T1ERG5|T1ERG5_HELRO
Uncharacterized protein
Search

tr|T1ERG6|T1ERG6_HELRO
Uncharacterized protein
Search

tr|T1ERG7|T1ERG7_HELRO
Uncharacterized protein
Search

tr|T1ERG8|T1ERG8_HELRO
Uncharacterized protein
Search

tr|T1ERG9|T1ERG9_HELRO
Uncharacterized protein
Search

tr|T1ERH0|T1ERH0_HELRO
Uncharacterized protein
Search

tr|T1ERH1|T1ERH1_HELRO
Uncharacterized protein
Search

0.43	GO:0006413	translational initiation
0.41	GO:0048015	phosphatidylinositol-mediated signaling
0.41	GO:0006352	DNA-templated transcription, initiation
0.41	GO:0070647	protein modification by small protein conjugation or removal
0.40	GO:0007616	long-term memory
0.40	GO:0046854	phosphatidylinositol phosphorylation
0.39	GO:0001522	pseudouridine synthesis
0.38	GO:0006914	autophagy
0.38	GO:0006508	proteolysis
0.38	GO:0055085	transmembrane transport

0.44	GO:0046983	protein dimerization activity
0.43	GO:0003743	translation initiation factor activity
0.40	GO:0140135	mechanosensitive cation channel activity
0.40	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.39	GO:0004430	1-phosphatidylinositol 4-kinase activity
0.39	GO:0008017	microtubule binding
0.39	GO:0030570	pectate lyase activity
0.39	GO:0004652	polynucleotide adenylyltransferase activity
0.38	GO:0003712	transcription cofactor activity
0.38	GO:0046873	metal ion transmembrane transporter activity

0.46	GO:0000124	SAGA complex
0.44	GO:0046695	SLIK (SAGA-like) complex
0.44	GO:0005669	transcription factor TFIID complex
0.38	GO:0043005	neuron projection
0.36	GO:0005576	extracellular region
0.36	GO:0005737	cytoplasm
0.35	GO:0030529	intracellular ribonucleoprotein complex
0.35	GO:0043232	intracellular non-membrane-bounded organelle
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.40	EC:3.4.19.12	GO:0036459
0.39	KEGG:R03361	GO:0004430

tr|T1ERH2|T1ERH2_HELRO
Uncharacterized protein
Search

tr|T1ERH3|T1ERH3_HELRO
Uncharacterized protein
Search

tr|T1ERH4|T1ERH4_HELRO
Uncharacterized protein
Search

tr|T1ERH5|T1ERH5_HELRO
Uncharacterized protein
Search

tr|T1ERH6|T1ERH6_HELRO
Uncharacterized protein
Search

tr|T1ERH7|T1ERH7_HELRO
Uncharacterized protein
Search

LOC106155694

0.93	inactive dipeptidyl peptidase 10-like

0.61	GO:0006508	proteolysis
0.55	GO:0010716	negative regulation of extracellular matrix disassembly
0.55	GO:0036343	psychomotor behavior
0.54	GO:0033632	regulation of cell-cell adhesion mediated by integrin
0.53	GO:0035641	locomotory exploration behavior
0.53	GO:0031295	T cell costimulation
0.53	GO:0001662	behavioral fear response
0.52	GO:0043542	endothelial cell migration
0.51	GO:0042110	T cell activation
0.50	GO:0001666	response to hypoxia

0.67	GO:0017171	serine hydrolase activity
0.62	GO:0070011	peptidase activity, acting on L-amino acid peptides
0.53	GO:0104005	hijacked molecular function
0.51	GO:0002020	protease binding
0.48	GO:0042803	protein homodimerization activity
0.47	GO:0005102	receptor binding
0.34	GO:0005518	collagen binding
0.34	GO:0042277	peptide binding
0.33	GO:0030545	receptor regulator activity

0.54	GO:0071438	invadopodium membrane
0.54	GO:0046581	intercellular canaliculus
0.51	GO:0030027	lamellipodium
0.50	GO:0016324	apical plasma membrane
0.50	GO:0030139	endocytic vesicle
0.48	GO:0009986	cell surface
0.41	GO:0098805	whole membrane
0.41	GO:0044437	vacuolar part
0.40	GO:0031256	leading edge membrane
0.39	GO:0098588	bounding membrane of organelle

tr|T1ERH8|T1ERH8_HELRO
Uncharacterized protein
Search

tr|T1ERH9|T1ERH9_HELRO
Uncharacterized protein
Search

MIPEP

0.67	Mitochondrial intermediate peptidase

0.83	GO:0006627	protein processing involved in protein targeting to mitochondrion
0.40	GO:0006518	peptide metabolic process
0.34	GO:0006672	ceramide metabolic process
0.34	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.34	GO:0002098	tRNA wobble uridine modification

0.70	GO:0004222	metalloendopeptidase activity
0.54	GO:0046872	metal ion binding
0.33	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides

0.75	GO:0005759	mitochondrial matrix
0.34	GO:0033588	Elongator holoenzyme complex
0.30	GO:0016020	membrane

0.70

EC:3.4.24

GO:0004222

tr|T1ERI0|T1ERI0_HELRO
Uncharacterized protein
Search

tr|T1ERI1|T1ERI1_HELRO
Uncharacterized protein
Search

tr|T1ERI2|T1ERI2_HELRO
Uncharacterized protein
Search

0.59	GO:0043044	ATP-dependent chromatin remodeling
0.42	GO:0050794	regulation of cellular process
0.40	GO:0010556	regulation of macromolecule biosynthetic process
0.40	GO:0051171	regulation of nitrogen compound metabolic process
0.40	GO:0080090	regulation of primary metabolic process
0.40	GO:0010468	regulation of gene expression
0.40	GO:0050896	response to stimulus
0.39	GO:0023052	signaling
0.39	GO:0031156	regulation of sorocarp development
0.39	GO:0046136	positive regulation of vitamin metabolic process

0.46	GO:0030554	adenyl nucleotide binding
0.45	GO:0097367	carbohydrate derivative binding
0.45	GO:0008144	drug binding
0.45	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0003700	DNA binding transcription factor activity
0.40	GO:0004888	transmembrane signaling receptor activity
0.38	GO:0003676	nucleic acid binding
0.38	GO:0004386	helicase activity
0.38	GO:0004402	histone acetyltransferase activity
0.38	GO:0004674	protein serine/threonine kinase activity

0.39	GO:0005815	microtubule organizing center
0.38	GO:0005881	cytoplasmic microtubule
0.35	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.38

EC:2.3.1.48

GO:0004402

tr|T1ERI3|T1ERI3_HELRO
Uncharacterized protein
Search

tr|T1ERI4|T1ERI4_HELRO
Uncharacterized protein
Search

tr|T1ERI5|T1ERI5_HELRO
Uncharacterized protein
Search

tr|T1ERI6|T1ERI6_HELRO
Uncharacterized protein
Search

MPP5

0.87	Membrane palmitoylated protein 5

0.79	GO:0070830	bicellular tight junction assembly
0.78	GO:0090162	establishment of epithelial cell polarity
0.49	GO:0035750	protein localization to myelin sheath abaxonal region
0.48	GO:0032287	peripheral nervous system myelin maintenance
0.46	GO:0002011	morphogenesis of an epithelial sheet
0.38	GO:0032259	methylation
0.37	GO:0016310	phosphorylation
0.35	GO:0016332	establishment or maintenance of polarity of embryonic epithelium
0.34	GO:0045186	zonula adherens assembly
0.34	GO:0045176	apical protein localization

0.44	GO:0019904	protein domain specific binding
0.38	GO:0016301	kinase activity
0.38	GO:0008168	methyltransferase activity

0.48	GO:0043219	lateral loop
0.48	GO:0035749	myelin sheath adaxonal region
0.48	GO:0043220	Schmidt-Lanterman incisure
0.46	GO:0005913	cell-cell adherens junction
0.39	GO:0043234	protein complex
0.38	GO:0005886	plasma membrane
0.36	GO:0005737	cytoplasm
0.34	GO:0043296	apical junction complex
0.34	GO:0045177	apical part of cell
0.30	GO:0016021	integral component of membrane

0.38

GO:0008168

tr|T1ERI7|T1ERI7_HELRO
Uncharacterized protein
Search

tr|T1ERI8|T1ERI8_HELRO
Uncharacterized protein
Search

0.45	GO:0035646	endosome to melanosome transport
0.45	GO:0035544	negative regulation of SNARE complex assembly
0.44	GO:1990126	retrograde transport, endosome to plasma membrane
0.44	GO:0050775	positive regulation of dendrite morphogenesis
0.44	GO:0045022	early endosome to late endosome transport
0.44	GO:2000678	negative regulation of transcription regulatory region DNA binding
0.43	GO:0035914	skeletal muscle cell differentiation
0.42	GO:0048812	neuron projection morphogenesis
0.41	GO:0000122	negative regulation of transcription by RNA polymerase II
0.40	GO:0006468	protein phosphorylation

0.47	GO:0003723	RNA binding
0.42	GO:0000149	SNARE binding
0.42	GO:0017137	Rab GTPase binding
0.41	GO:0005085	guanyl-nucleotide exchange factor activity
0.40	GO:0004672	protein kinase activity
0.40	GO:0046914	transition metal ion binding
0.38	GO:0030554	adenyl nucleotide binding
0.37	GO:0032555	purine ribonucleotide binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding

0.51	GO:1905369	endopeptidase complex
0.45	GO:0097422	tubular endosome
0.45	GO:0043234	protein complex
0.44	GO:0005634	nucleus
0.43	GO:0042470	melanosome
0.43	GO:0005829	cytosol
0.42	GO:0005770	late endosome
0.42	GO:0005769	early endosome
0.42	GO:0005764	lysosome
0.41	GO:0043005	neuron projection

tr|T1ERI9|T1ERI9_HELRO
Uncharacterized protein
Search

tr|T1ERJ0|T1ERJ0_HELRO
Uncharacterized protein
Search

tr|T1ERJ1|T1ERJ1_HELRO
Uncharacterized protein
Search

tr|T1ERJ2|T1ERJ2_HELRO
Uncharacterized protein
Search

0.42	GO:0007018	microtubule-based movement
0.37	GO:0006907	pinocytosis
0.37	GO:0031929	TOR signaling
0.36	GO:0061512	protein localization to cilium
0.35	GO:0016310	phosphorylation
0.34	GO:0019538	protein metabolic process
0.34	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.33	GO:0032502	developmental process
0.33	GO:0006518	peptide metabolic process
0.33	GO:0043604	amide biosynthetic process

0.42	GO:0003777	microtubule motor activity
0.41	GO:0003676	nucleic acid binding
0.41	GO:0008270	zinc ion binding
0.35	GO:0016301	kinase activity
0.35	GO:0035091	phosphatidylinositol binding
0.35	GO:0004252	serine-type endopeptidase activity
0.34	GO:0004527	exonuclease activity
0.33	GO:0022803	passive transmembrane transporter activity
0.33	GO:0003735	structural constituent of ribosome
0.33	GO:0016773	phosphotransferase activity, alcohol group as acceptor

0.41	GO:0005634	nucleus
0.37	GO:0031931	TORC1 complex
0.36	GO:0019013	viral nucleocapsid
0.35	GO:0030529	intracellular ribonucleoprotein complex
0.35	GO:0005929	cilium
0.34	GO:0030286	dynein complex
0.33	GO:0005886	plasma membrane
0.32	GO:0044444	cytoplasmic part
0.30	GO:0016021	integral component of membrane

0.35

GO:0004252

tr|T1ERJ3|T1ERJ3_HELRO
Uncharacterized protein
Search

tr|T1ERJ4|T1ERJ4_HELRO
Uncharacterized protein
Search

0.45	GO:0016042	lipid catabolic process
0.44	GO:0006397	mRNA processing
0.43	GO:0060255	regulation of macromolecule metabolic process
0.43	GO:0031323	regulation of cellular metabolic process
0.43	GO:0051171	regulation of nitrogen compound metabolic process
0.43	GO:0080090	regulation of primary metabolic process
0.43	GO:0009889	regulation of biosynthetic process
0.40	GO:0016180	snRNA processing
0.40	GO:0099120	socially cooperative development
0.38	GO:1901261	regulation of sorocarp spore cell differentiation

0.46	GO:0003723	RNA binding
0.45	GO:0003700	DNA binding transcription factor activity
0.40	GO:0046872	metal ion binding
0.39	GO:0016787	hydrolase activity
0.37	GO:0017076	purine nucleotide binding
0.37	GO:0032553	ribonucleotide binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0004672	protein kinase activity
0.36	GO:0008144	drug binding
0.36	GO:0004871	signal transducer activity

0.41	GO:0005634	nucleus
0.39	GO:0070013	intracellular organelle lumen
0.39	GO:0000428	DNA-directed RNA polymerase complex
0.38	GO:0000785	chromatin
0.36	GO:0043234	protein complex
0.36	GO:1904949	ATPase complex
0.35	GO:0005811	lipid droplet
0.35	GO:0000159	protein phosphatase type 2A complex
0.35	GO:0033202	DNA helicase complex
0.35	GO:0000139	Golgi membrane

0.39

GO:0016787

tr|T1ERJ5|T1ERJ5_HELRO
Uncharacterized protein
Search

tr|T1ERJ6|T1ERJ6_HELRO
Uncharacterized protein
Search

tr|T1ERJ7|T1ERJ7_HELRO
Uncharacterized protein
Search

0.45	GO:0032259	methylation
0.44	GO:0042462	eye photoreceptor cell development
0.44	GO:0060041	retina development in camera-type eye
0.43	GO:0007601	visual perception
0.42	GO:0006400	tRNA modification
0.41	GO:0007155	cell adhesion
0.39	GO:0006468	protein phosphorylation
0.39	GO:0006629	lipid metabolic process
0.38	GO:0006508	proteolysis

0.53	GO:0008061	chitin binding
0.51	GO:0052905	tRNA (guanine(9)-N(1))-methyltransferase activity
0.41	GO:0140096	catalytic activity, acting on a protein
0.39	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.39	GO:0008270	zinc ion binding
0.38	GO:0016301	kinase activity
0.38	GO:0016787	hydrolase activity
0.37	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding

0.44	GO:0005576	extracellular region
0.41	GO:0005618	cell wall
0.30	GO:0016020	membrane

0.51

EC:2.1.1.221

GO:0052905

tr|T1ERJ8|T1ERJ8_HELRO
Uncharacterized protein
Search

tr|T1ERJ9|T1ERJ9_HELRO
Uncharacterized protein
Search

tr|T1ERK0|T1ERK0_HELRO
Uncharacterized protein
Search

tr|T1ERK1|T1ERK1_HELRO
Uncharacterized protein
Search

tr|T1ERK2|T1ERK2_HELRO
Uncharacterized protein
Search

0.52	GO:1902600	hydrogen ion transmembrane transport
0.39	GO:0046854	phosphatidylinositol phosphorylation
0.38	GO:0001189	RNA polymerase I transcriptional preinitiation complex assembly
0.38	GO:0060255	regulation of macromolecule metabolic process
0.38	GO:0007018	microtubule-based movement
0.37	GO:0070544	histone H3-K36 demethylation
0.37	GO:0080090	regulation of primary metabolic process
0.37	GO:0031326	regulation of cellular biosynthetic process
0.37	GO:0051171	regulation of nitrogen compound metabolic process
0.36	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process

0.70	GO:0030171	voltage-gated proton channel activity
0.41	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity
0.40	GO:0003676	nucleic acid binding
0.39	GO:0046872	metal ion binding
0.38	GO:0003777	microtubule motor activity
0.37	GO:0051864	histone demethylase activity (H3-K36 specific)
0.36	GO:0003700	DNA binding transcription factor activity
0.36	GO:0016887	ATPase activity
0.35	GO:0032555	purine ribonucleotide binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.55	GO:0005887	integral component of plasma membrane
0.40	GO:0005634	nucleus
0.38	GO:0020011	apicoplast
0.37	GO:0031974	membrane-enclosed lumen
0.37	GO:0000974	Prp19 complex
0.36	GO:0005667	transcription factor complex
0.36	GO:0044446	intracellular organelle part
0.34	GO:0043232	intracellular non-membrane-bounded organelle
0.34	GO:1902494	catalytic complex
0.34	GO:0030529	intracellular ribonucleoprotein complex

0.41	EC:2.7.1.68	GO:0016308
0.41	KEGG:R03469	GO:0016308

tr|T1ERK3|T1ERK3_HELRO
Uncharacterized protein
Search

tr|T1ERK4|T1ERK4_HELRO
Uncharacterized protein
Search

0.71	Tigger transposable element-derived protein (Fragment)

0.35	GO:0035556	intracellular signal transduction
0.34	GO:0006413	translational initiation
0.33	GO:0015074	DNA integration
0.33	GO:0006508	proteolysis

0.51	GO:0003676	nucleic acid binding
0.36	GO:0046872	metal ion binding
0.34	GO:0008234	cysteine-type peptidase activity

0.32	GO:0005622	intracellular
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:3.4

GO:0008234

tr|T1ERK5|T1ERK5_HELRO
Uncharacterized protein
Search

0.49	GO:0097659	nucleic acid-templated transcription
0.47	GO:0010467	gene expression
0.46	GO:0034645	cellular macromolecule biosynthetic process

0.47

GO:0016779

nucleotidyltransferase activity

0.30

GO:0031224

intrinsic component of membrane

0.47

EC:2.7.7

GO:0016779

tr|T1ERK6|T1ERK6_HELRO
Uncharacterized protein
Search

tr|T1ERK7|T1ERK7_HELRO
Uncharacterized protein
Search

0.50	tRNA-specific adenosine deaminase (Fragment)

0.63	GO:0006396	RNA processing
0.39	GO:0021618	hypoglossal nerve morphogenesis
0.39	GO:0097049	motor neuron apoptotic process
0.39	GO:0021965	spinal cord ventral commissure morphogenesis
0.39	GO:0061744	motor behavior
0.38	GO:0044387	negative regulation of protein kinase activity by regulation of protein phosphorylation
0.38	GO:0021610	facial nerve morphogenesis
0.38	GO:0050884	neuromuscular process controlling posture
0.38	GO:0060384	innervation
0.38	GO:0045070	positive regulation of viral genome replication

0.79	GO:0004000	adenosine deaminase activity
0.59	GO:0003723	RNA binding
0.35	GO:0004824	lysine-tRNA ligase activity
0.35	GO:0016491	oxidoreductase activity
0.34	GO:0008146	sulfotransferase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.36	GO:0005730	nucleolus
0.36	GO:0005654	nucleoplasm
0.35	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.79

EC:3.5.4.4

GO:0004000

tr|T1ERK8|T1ERK8_HELRO
Uncharacterized protein
Search

tr|T1ERK9|T1ERK9_HELRO
Uncharacterized protein
Search

tr|T1ERL0|T1ERL0_HELRO
Uncharacterized protein
Search

tr|T1ERL1|T1ERL1_HELRO
Uncharacterized protein
Search

tr|T1ERL2|T1ERL2_HELRO
Uncharacterized protein
Search

0.68	GO:0007399	nervous system development
0.66	GO:0120036	plasma membrane bounded cell projection organization
0.65	GO:0048468	cell development
0.59	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.57	GO:0071206	establishment of protein localization to juxtaparanode region of axon
0.56	GO:0060168	positive regulation of adenosine receptor signaling pathway
0.55	GO:0032536	regulation of cell projection size
0.54	GO:0050808	synapse organization
0.54	GO:0006935	chemotaxis
0.54	GO:0010954	positive regulation of protein processing

0.53	GO:0043621	protein self-association
0.50	GO:0005042	netrin receptor activity
0.46	GO:0030246	carbohydrate binding
0.38	GO:0005021	vascular endothelial growth factor-activated receptor activity
0.37	GO:0086080	protein binding involved in heterotypic cell-cell adhesion
0.37	GO:0005509	calcium ion binding
0.36	GO:0030554	adenyl nucleotide binding
0.36	GO:0097367	carbohydrate derivative binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0008144	drug binding

0.55	GO:0044224	juxtaparanode region of axon
0.55	GO:0033268	node of Ranvier
0.52	GO:0043209	myelin sheath
0.51	GO:0005887	integral component of plasma membrane
0.51	GO:0043025	neuronal cell body
0.49	GO:0034705	potassium channel complex
0.49	GO:0009986	cell surface
0.38	GO:0031225	anchored component of membrane
0.37	GO:0033010	paranodal junction
0.37	GO:0043194	axon initial segment

0.33

GO:0004674

tr|T1ERL3|T1ERL3_HELRO
Uncharacterized protein
Search

tr|T1ERL4|T1ERL4_HELRO
Uncharacterized protein
Search

tr|T1ERL5|T1ERL5_HELRO
Uncharacterized protein
Search

tr|T1ERL6|T1ERL6_HELRO
Uncharacterized protein
Search

tr|T1ERL7|T1ERL7_HELRO
Uncharacterized protein
Search

AADAT

0.50	Pyridoxal phosphate-dependent transferase

0.48	GO:0009058	biosynthetic process
0.42	GO:0097052	L-kynurenine metabolic process
0.42	GO:0006103	2-oxoglutarate metabolic process
0.40	GO:0006536	glutamate metabolic process
0.37	GO:0033512	L-lysine catabolic process to acetyl-CoA via saccharopine
0.37	GO:0019441	tryptophan catabolic process to kynurenine
0.34	GO:0006850	mitochondrial pyruvate transmembrane transport
0.33	GO:0097502	mannosylation
0.32	GO:0043413	macromolecule glycosylation
0.32	GO:0009100	glycoprotein metabolic process

0.66	GO:0030170	pyridoxal phosphate binding
0.49	GO:0008483	transaminase activity
0.41	GO:0042803	protein homodimerization activity
0.33	GO:0000030	mannosyltransferase activity
0.32	GO:0008168	methyltransferase activity
0.32	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.32	GO:0003676	nucleic acid binding

0.37	GO:0005739	mitochondrion
0.33	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.49

EC:2.6.1

GO:0008483

tr|T1ERL8|T1ERL8_HELRO
Uncharacterized protein
Search

tr|T1ERL9|T1ERL9_HELRO
Uncharacterized protein
Search

0.79	[Protein ADP-ribosylarginine] hydrolase-like protein 1 isoform 1 (Fragment)

0.79

GO:0051725

protein de-ADP-ribosylation

0.79	GO:0003875	ADP-ribosylarginine hydrolase activity
0.58	GO:0000287	magnesium ion binding

0.79

EC:3.2.2.19

GO:0003875

tr|T1ERM0|T1ERM0_HELRO
Uncharacterized protein
Search

tr|T1ERM1|T1ERM1_HELRO
Uncharacterized protein
Search

tr|T1ERM2|T1ERM2_HELRO
Uncharacterized protein
Search

tr|T1ERM3|T1ERM3_HELRO
Uncharacterized protein
Search

tr|T1ERM4|T1ERM4_HELRO
Uncharacterized protein
Search

tr|T1ERM5|T1ERM5_HELRO
Uncharacterized protein
Search

0.58	GO:0006508	proteolysis
0.35	GO:0051044	positive regulation of membrane protein ectodomain proteolysis
0.35	GO:0007528	neuromuscular junction development
0.35	GO:0071432	peptide mating pheromone maturation involved in conjugation with cellular fusion
0.35	GO:0008283	cell proliferation
0.34	GO:0016477	cell migration
0.34	GO:0052548	regulation of endopeptidase activity

0.66	GO:0004222	metalloendopeptidase activity
0.54	GO:0046872	metal ion binding
0.36	GO:0048408	epidermal growth factor binding
0.34	GO:0016757	transferase activity, transferring glycosyl groups

0.34	GO:0009986	cell surface
0.34	GO:0005829	cytosol
0.34	GO:0019898	extrinsic component of membrane
0.33	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.66

EC:3.4.24

GO:0004222

tr|T1ERM6|T1ERM6_HELRO
Uncharacterized protein
Search

0.44	Mitochondrial NADH:ubiquinone oxidoreductase ESSS subunit

0.37

GO:0043547

positive regulation of GTPase activity

0.38	GO:1902936	phosphatidylinositol bisphosphate binding
0.37	GO:0005096	GTPase activator activity
0.34	GO:0046872	metal ion binding

0.30

GO:0044425

membrane part

tr|T1ERM7|T1ERM7_HELRO
Uncharacterized protein
Search

0.68	GO:0071805	potassium ion transmembrane transport
0.42	GO:0030322	stabilization of membrane potential
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.70	GO:0005267	potassium channel activity
0.42	GO:0022842	narrow pore channel activity
0.34	GO:0022843	voltage-gated cation channel activity
0.33	GO:0099094	ligand-gated cation channel activity

0.37	GO:0005887	integral component of plasma membrane
0.33	GO:0005634	nucleus

tr|T1ERM8|T1ERM8_HELRO
Uncharacterized protein
Search

tr|T1ERM9|T1ERM9_HELRO
Uncharacterized protein
Search

tr|T1ERN0|T1ERN0_HELRO
Uncharacterized protein
Search

0.10	Thrombospondin type 3 repeat-containing protein

0.49	GO:0007155	cell adhesion
0.49	GO:0030198	extracellular matrix organization
0.41	GO:0006457	protein folding
0.39	GO:0006950	response to stress
0.34	GO:0046776	suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I
0.33	GO:0036211	protein modification process
0.33	GO:0044267	cellular protein metabolic process
0.33	GO:0035725	sodium ion transmembrane transport
0.33	GO:0006816	calcium ion transport
0.33	GO:0016310	phosphorylation

0.68	GO:0005509	calcium ion binding
0.42	GO:0051082	unfolded protein binding
0.38	GO:0032555	purine ribonucleotide binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0030554	adenyl nucleotide binding
0.37	GO:0008144	drug binding
0.35	GO:0042288	MHC class I protein binding
0.35	GO:0032550	purine ribonucleoside binding
0.35	GO:0019001	guanyl nucleotide binding
0.33	GO:0004674	protein serine/threonine kinase activity

0.46	GO:0031012	extracellular matrix
0.38	GO:0030312	external encapsulating structure
0.36	GO:0019867	outer membrane
0.36	GO:0030313	cell envelope
0.34	GO:0044165	host cell endoplasmic reticulum
0.31	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.33

GO:0004674

tr|T1ERN1|T1ERN1_HELRO
Uncharacterized protein
Search

tr|T1ERN2|T1ERN2_HELRO
Uncharacterized protein
Search

tr|T1ERN3|T1ERN3_HELRO
Uncharacterized protein
Search

tr|T1ERN4|T1ERN4_HELRO
Uncharacterized protein
Search

tr|T1ERN5|T1ERN5_HELRO
Uncharacterized protein
Search

0.44	GO:2001141	regulation of RNA biosynthetic process
0.44	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.43	GO:0010468	regulation of gene expression
0.42	GO:0016569	covalent chromatin modification
0.41	GO:0018393	internal peptidyl-lysine acetylation
0.38	GO:0006468	protein phosphorylation
0.38	GO:0006511	ubiquitin-dependent protein catabolic process
0.38	GO:0099120	socially cooperative development
0.38	GO:0007165	signal transduction
0.37	GO:0046578	regulation of Ras protein signal transduction

0.45	GO:0003700	DNA binding transcription factor activity
0.41	GO:0004402	histone acetyltransferase activity
0.39	GO:0017076	purine nucleotide binding
0.39	GO:0097367	carbohydrate derivative binding
0.39	GO:0005515	protein binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0004672	protein kinase activity
0.38	GO:0003676	nucleic acid binding
0.38	GO:0008144	drug binding
0.36	GO:0016787	hydrolase activity

0.40	GO:0008540	proteasome regulatory particle, base subcomplex
0.39	GO:0005634	nucleus
0.37	GO:0044446	intracellular organelle part
0.37	GO:0070013	intracellular organelle lumen
0.36	GO:0005856	cytoskeleton
0.35	GO:1990234	transferase complex
0.35	GO:0020011	apicoplast
0.35	GO:0044233	ER-mitochondrion membrane contact site
0.35	GO:0017053	transcriptional repressor complex
0.35	GO:0033202	DNA helicase complex

0.41	EC:2.3.1.48	GO:0004402
0.34	KEGG:R01776	GO:0004414

tr|T1ERN6|T1ERN6_HELRO
Uncharacterized protein
Search

0.41	GO:0071805	potassium ion transmembrane transport
0.41	GO:0031087	deadenylation-independent decapping of nuclear-transcribed mRNA
0.40	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.40	GO:0036211	protein modification process
0.39	GO:0006629	lipid metabolic process
0.38	GO:0044267	cellular protein metabolic process
0.38	GO:0043413	macromolecule glycosylation
0.38	GO:0009101	glycoprotein biosynthetic process
0.37	GO:0006364	rRNA processing
0.36	GO:0032259	methylation

0.46	GO:0008270	zinc ion binding
0.43	GO:0000166	nucleotide binding
0.42	GO:0008556	potassium-transporting ATPase activity
0.42	GO:0043168	anion binding
0.42	GO:0097367	carbohydrate derivative binding
0.41	GO:0008144	drug binding
0.40	GO:0003676	nucleic acid binding
0.39	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.39	GO:0016706	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
0.38	GO:0048029	monosaccharide binding

0.40	GO:0000932	P-body
0.30	GO:0016020	membrane

0.42	EC:3.6.3.12	GO:0008556
0.38	KEGG:R03876	GO:0004842

tr|T1ERN7|T1ERN7_HELRO
Uncharacterized protein
Search

tr|T1ERN8|T1ERN8_HELRO
Uncharacterized protein
Search

tr|T1ERN9|T1ERN9_HELRO
Uncharacterized protein
Search

tr|T1ERP0|T1ERP0_HELRO
Uncharacterized protein
Search

tr|T1ERP1|T1ERP1_HELRO
Uncharacterized protein
Search

tr|T1ERP2|T1ERP2_HELRO
Uncharacterized protein
Search

tr|T1ERP3|T1ERP3_HELRO
Uncharacterized protein
Search

0.56	GO:0016042	lipid catabolic process
0.51	GO:0035556	intracellular signal transduction
0.48	GO:0002376	immune system process
0.46	GO:1902633	1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolic process
0.45	GO:0006898	receptor-mediated endocytosis
0.45	GO:1902477	regulation of defense response to bacterium, incompatible interaction
0.43	GO:0007194	negative regulation of adenylate cyclase activity
0.43	GO:0042993	positive regulation of transcription factor import into nucleus
0.43	GO:0050830	defense response to Gram-positive bacterium
0.42	GO:0008340	determination of adult lifespan

0.62	GO:0004435	phosphatidylinositol phospholipase C activity
0.51	GO:0004871	signal transducer activity
0.49	GO:0005044	scavenger receptor activity
0.48	GO:0030247	polysaccharide binding
0.43	GO:0005085	guanyl-nucleotide exchange factor activity
0.40	GO:0017016	Ras GTPase binding
0.37	GO:0016301	kinase activity
0.37	GO:0003676	nucleic acid binding
0.37	GO:0001026	TFIIIB-type transcription factor activity
0.36	GO:0097367	carbohydrate derivative binding

0.41	GO:0005622	intracellular
0.37	GO:0043227	membrane-bounded organelle
0.36	GO:0032991	macromolecular complex
0.35	GO:0044422	organelle part
0.34	GO:0005576	extracellular region
0.34	GO:0099512	supramolecular fiber
0.34	GO:0012505	endomembrane system
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0031225	anchored component of membrane
0.33	GO:0005618	cell wall

0.62	EC:3.1.4.11	GO:0004435
0.62	KEGG:R03435	GO:0004435

tr|T1ERP4|T1ERP4_HELRO
Uncharacterized protein
Search

0.53	GO:0006413	translational initiation
0.48	GO:0006886	intracellular protein transport
0.41	GO:0007020	microtubule nucleation
0.38	GO:0006468	protein phosphorylation
0.37	GO:0007267	cell-cell signaling
0.37	GO:0018212	peptidyl-tyrosine modification
0.37	GO:0006368	transcription elongation from RNA polymerase II promoter
0.37	GO:0043044	ATP-dependent chromatin remodeling
0.37	GO:0007275	multicellular organism development
0.37	GO:0000122	negative regulation of transcription by RNA polymerase II

0.54	GO:0003743	translation initiation factor activity
0.51	GO:0035091	phosphatidylinositol binding
0.41	GO:0043015	gamma-tubulin binding
0.39	GO:0032559	adenyl ribonucleotide binding
0.39	GO:0003729	mRNA binding
0.39	GO:0008144	drug binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0004672	protein kinase activity
0.37	GO:0004075	biotin carboxylase activity
0.37	GO:0042626	ATPase activity, coupled to transmembrane movement of substances

0.41	GO:0000922	spindle pole
0.40	GO:0005815	microtubule organizing center
0.39	GO:0005874	microtubule
0.38	GO:0032044	DSIF complex
0.38	GO:0022627	cytosolic small ribosomal subunit
0.37	GO:0005615	extracellular space
0.36	GO:0019013	viral nucleocapsid
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.37

EC:6.3.4.14

GO:0004075

tr|T1ERP5|T1ERP5_HELRO
Uncharacterized protein
Search

0.46	GO:0016567	protein ubiquitination
0.43	GO:0060255	regulation of macromolecule metabolic process
0.43	GO:0031326	regulation of cellular biosynthetic process
0.43	GO:0051171	regulation of nitrogen compound metabolic process
0.43	GO:0080090	regulation of primary metabolic process
0.38	GO:0006468	protein phosphorylation
0.38	GO:0018193	peptidyl-amino acid modification
0.38	GO:0046700	heterocycle catabolic process
0.38	GO:0044270	cellular nitrogen compound catabolic process
0.38	GO:1901361	organic cyclic compound catabolic process

0.47	GO:0004842	ubiquitin-protein transferase activity
0.44	GO:0003700	DNA binding transcription factor activity
0.39	GO:0008270	zinc ion binding
0.38	GO:0004672	protein kinase activity
0.38	GO:0018024	histone-lysine N-methyltransferase activity
0.38	GO:0004037	allantoicase activity
0.36	GO:0017076	purine nucleotide binding
0.36	GO:0097367	carbohydrate derivative binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0016874	ligase activity

0.38	GO:0005634	nucleus
0.36	GO:0000932	P-body
0.36	GO:0070013	intracellular organelle lumen
0.35	GO:0000178	exosome (RNase complex)
0.35	GO:0030117	membrane coat
0.35	GO:0044446	intracellular organelle part
0.34	GO:0035068	micro-ribonucleoprotein complex
0.34	GO:0005667	transcription factor complex
0.34	GO:0031248	protein acetyltransferase complex
0.33	GO:0005794	Golgi apparatus

0.38	EC:2.1.1.43	GO:0018024
0.47	KEGG:R03876	GO:0004842

tr|T1ERP6|T1ERP6_HELRO
Uncharacterized protein
Search

tr|T1ERP7|T1ERP7_HELRO
Uncharacterized protein
Search

tr|T1ERP8|T1ERP8_HELRO
Uncharacterized protein
Search

tr|T1ERP9|T1ERP9_HELRO
Uncharacterized protein
Search

0.48	GO:0044265	cellular macromolecule catabolic process
0.46	GO:0016579	protein deubiquitination
0.44	GO:0030163	protein catabolic process
0.42	GO:0034655	nucleobase-containing compound catabolic process
0.38	GO:0016070	RNA metabolic process
0.38	GO:0010468	regulation of gene expression
0.38	GO:1903506	regulation of nucleic acid-templated transcription
0.38	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.37	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.36	GO:0016310	phosphorylation

0.49	GO:0046982	protein heterodimerization activity
0.46	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.44	GO:0003724	RNA helicase activity
0.43	GO:0003676	nucleic acid binding
0.42	GO:0008270	zinc ion binding
0.39	GO:0032559	adenyl ribonucleotide binding
0.39	GO:0008144	drug binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0140110	transcription regulator activity
0.37	GO:0016301	kinase activity

0.44	GO:0005634	nucleus
0.40	GO:0005667	transcription factor complex
0.37	GO:0044446	intracellular organelle part
0.35	GO:0055087	Ski complex
0.35	GO:0033202	DNA helicase complex
0.34	GO:0005694	chromosome
0.34	GO:0031974	membrane-enclosed lumen
0.34	GO:1904949	ATPase complex
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.46

EC:3.4.19.12

GO:0036459

tr|T1ERQ0|T1ERQ0_HELRO
Uncharacterized protein
Search

0.36

GO:0006468

protein phosphorylation

0.53	GO:0046872	metal ion binding
0.36	GO:0004672	protein kinase activity
0.35	GO:0030554	adenyl nucleotide binding
0.35	GO:0097367	carbohydrate derivative binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

tr|T1ERQ1|T1ERQ1_HELRO
Uncharacterized protein
Search

tr|T1ERQ2|T1ERQ2_HELRO
Uncharacterized protein
Search

TRAPPC1

0.65	Transport protein particle trapp complex subunit

0.69	GO:0016192	vesicle-mediated transport
0.49	GO:0046907	intracellular transport
0.48	GO:0065009	regulation of molecular function
0.34	GO:0050880	regulation of blood vessel size
0.33	GO:0009966	regulation of signal transduction
0.32	GO:0006468	protein phosphorylation

0.57	GO:0017112	Rab guanyl-nucleotide exchange factor activity
0.34	GO:0005179	hormone activity
0.32	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.82	GO:0030008	TRAPP complex
0.55	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.52	GO:0044440	endosomal part
0.50	GO:0044431	Golgi apparatus part
0.36	GO:0005829	cytosol
0.33	GO:0005576	extracellular region

tr|T1ERQ3|T1ERQ3_HELRO
Uncharacterized protein
Search

tr|T1ERQ4|T1ERQ4_HELRO
Uncharacterized protein
Search

DCTD

0.62	Deoxycytidylate deaminase

0.63	GO:0006220	pyrimidine nucleotide metabolic process
0.39	GO:0009176	pyrimidine deoxyribonucleoside monophosphate metabolic process
0.38	GO:0009157	deoxyribonucleoside monophosphate biosynthetic process
0.38	GO:0046385	deoxyribose phosphate biosynthetic process
0.38	GO:0009394	2'-deoxyribonucleotide metabolic process
0.38	GO:0009263	deoxyribonucleotide biosynthetic process
0.38	GO:0009130	pyrimidine nucleoside monophosphate biosynthetic process
0.37	GO:0072528	pyrimidine-containing compound biosynthetic process
0.36	GO:0015949	nucleobase-containing small molecule interconversion

0.73	GO:0004132	dCMP deaminase activity
0.63	GO:0008270	zinc ion binding
0.41	GO:0042802	identical protein binding

0.38	GO:0070062	extracellular exosome
0.34	GO:0005829	cytosol

0.73

EC:3.5.4.12

GO:0004132

tr|T1ERQ5|T1ERQ5_HELRO
Uncharacterized protein
Search

tr|T1ERQ6|T1ERQ6_HELRO
Uncharacterized protein
Search

tr|T1ERQ7|T1ERQ7_HELRO
Uncharacterized protein
Search

0.44	GO:0070647	protein modification by small protein conjugation or removal
0.41	GO:0006508	proteolysis
0.41	GO:0043632	modification-dependent macromolecule catabolic process
0.41	GO:0044257	cellular protein catabolic process
0.41	GO:1903506	regulation of nucleic acid-templated transcription
0.41	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.40	GO:0010468	regulation of gene expression
0.40	GO:0007018	microtubule-based movement
0.39	GO:0006468	protein phosphorylation
0.38	GO:0009584	detection of visible light

0.44	GO:0140096	catalytic activity, acting on a protein
0.40	GO:0003777	microtubule motor activity
0.40	GO:0032550	purine ribonucleoside binding
0.40	GO:0032561	guanyl ribonucleotide binding
0.40	GO:0003700	DNA binding transcription factor activity
0.38	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0016301	kinase activity
0.38	GO:0016874	ligase activity
0.36	GO:0016775	phosphotransferase activity, nitrogenous group as acceptor

0.36	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.38

GO:0016773

tr|T1ERQ8|T1ERQ8_HELRO
Uncharacterized protein
Search

0.43	GO:0016114	terpenoid biosynthetic process
0.41	GO:0060255	regulation of macromolecule metabolic process
0.41	GO:0031326	regulation of cellular biosynthetic process
0.41	GO:0051171	regulation of nitrogen compound metabolic process
0.41	GO:0080090	regulation of primary metabolic process
0.41	GO:0006351	transcription, DNA-templated
0.40	GO:0002009	morphogenesis of an epithelium
0.40	GO:0046847	filopodium assembly
0.40	GO:0007275	multicellular organism development
0.39	GO:0009893	positive regulation of metabolic process

0.45	GO:0003676	nucleic acid binding
0.44	GO:0008661	1-deoxy-D-xylulose-5-phosphate synthase activity
0.41	GO:0005515	protein binding
0.40	GO:0140110	transcription regulator activity
0.39	GO:0008270	zinc ion binding
0.38	GO:0004491	methylmalonate-semialdehyde dehydrogenase (acylating) activity
0.37	GO:0003777	microtubule motor activity
0.37	GO:0140096	catalytic activity, acting on a protein
0.36	GO:0050825	ice binding
0.36	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.46	GO:0005634	nucleus
0.39	GO:0030175	filopodium
0.38	GO:0043025	neuronal cell body
0.38	GO:0031248	protein acetyltransferase complex
0.38	GO:0000428	DNA-directed RNA polymerase complex
0.38	GO:0005667	transcription factor complex
0.38	GO:0044446	intracellular organelle part
0.38	GO:1905368	peptidase complex
0.38	GO:0070013	intracellular organelle lumen
0.37	GO:0005856	cytoskeleton

0.44	EC:2.2.1.7	GO:0008661
0.44	KEGG:R05636	GO:0008661

tr|T1ERQ9|T1ERQ9_HELRO
Uncharacterized protein
Search

tr|T1ERR0|T1ERR0_HELRO
Uncharacterized protein
Search

tr|T1ERR1|T1ERR1_HELRO
Uncharacterized protein
Search

tr|T1ERR2|T1ERR2_HELRO
Uncharacterized protein
Search

tr|T1ERR3|T1ERR3_HELRO
Uncharacterized protein
Search

tr|T1ERR4|T1ERR4_HELRO
Uncharacterized protein
Search

tr|T1ERR5|T1ERR5_HELRO
Uncharacterized protein
Search

0.59	COMM domain containing 7

0.84	GO:0033209	tumor necrosis factor-mediated signaling pathway
0.84	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.70	GO:0045892	negative regulation of transcription, DNA-templated
0.39	GO:0006351	transcription, DNA-templated

0.85

GO:0051059

NF-kappaB binding

0.55	GO:0043231	intracellular membrane-bounded organelle
0.46	GO:0031982	vesicle
0.44	GO:0043230	extracellular organelle
0.42	GO:0005615	extracellular space
0.38	GO:0044444	cytoplasmic part

tr|T1ERR6|T1ERR6_HELRO
Uncharacterized protein
Search

tr|T1ERR7|T1ERR7_HELRO
Uncharacterized protein
Search

0.35	GO:0006364	rRNA processing
0.34	GO:0051602	response to electrical stimulus
0.34	GO:0007614	short-term memory
0.34	GO:0016319	mushroom body development
0.34	GO:0048678	response to axon injury
0.34	GO:0007616	long-term memory
0.34	GO:0007422	peripheral nervous system development
0.34	GO:1901215	negative regulation of neuron death
0.34	GO:0050808	synapse organization
0.33	GO:0048812	neuron projection morphogenesis

0.72	GO:0008201	heparin binding
0.53	GO:0046914	transition metal ion binding
0.34	GO:0005515	protein binding
0.33	GO:0019887	protein kinase regulator activity
0.33	GO:0016874	ligase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.37	GO:0030688	preribosome, small subunit precursor
0.34	GO:0005956	protein kinase CK2 complex
0.33	GO:0005576	extracellular region
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.33

EC:6

GO:0016874

tr|T1ERR8|T1ERR8_HELRO
Uncharacterized protein
Search

0.50	GO:0000256	allantoin catabolic process
0.40	GO:0034655	nucleobase-containing compound catabolic process
0.40	GO:0099120	socially cooperative development
0.40	GO:0006468	protein phosphorylation
0.40	GO:0060176	regulation of aggregation involved in sorocarp development
0.39	GO:0048519	negative regulation of biological process
0.39	GO:0016071	mRNA metabolic process
0.39	GO:0044265	cellular macromolecule catabolic process
0.39	GO:0098630	aggregation of unicellular organisms
0.38	GO:0060255	regulation of macromolecule metabolic process

0.51	GO:0004037	allantoicase activity
0.42	GO:0008270	zinc ion binding
0.40	GO:0017076	purine nucleotide binding
0.40	GO:0097367	carbohydrate derivative binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0004672	protein kinase activity
0.39	GO:0008144	drug binding
0.38	GO:0003676	nucleic acid binding
0.37	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.37	GO:0008047	enzyme activator activity

0.37	GO:0005634	nucleus
0.36	GO:0030014	CCR4-NOT complex
0.36	GO:0000932	P-body
0.35	GO:0005829	cytosol
0.35	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

0.51	EC:3.5.3.4	GO:0004037
0.51	KEGG:R02422	GO:0004037

tr|T1ERR9|T1ERR9_HELRO
Uncharacterized protein
Search

0.56	GO:0007399	nervous system development
0.50	GO:0010951	negative regulation of endopeptidase activity
0.44	GO:0060026	convergent extension
0.43	GO:0001944	vasculature development
0.36	GO:0042395	ecdysis, collagen and cuticulin-based cuticle
0.35	GO:0002119	nematode larval development
0.35	GO:0010171	body morphogenesis
0.35	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.35	GO:0120036	plasma membrane bounded cell projection organization
0.35	GO:0048468	cell development

0.82	GO:0008201	heparin binding
0.58	GO:0046914	transition metal ion binding
0.51	GO:0004867	serine-type endopeptidase inhibitor activity
0.34	GO:0005515	protein binding
0.33	GO:0004499	N,N-dimethylaniline monooxygenase activity
0.32	GO:0050661	NADP binding
0.32	GO:0050660	flavin adenine dinucleotide binding

0.35	GO:0043025	neuronal cell body
0.35	GO:0043005	neuron projection
0.34	GO:0031410	cytoplasmic vesicle
0.33	GO:0005576	extracellular region
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.33

EC:1.14.13.8

GO:0004499

tr|T1ERS0|T1ERS0_HELRO
Uncharacterized protein
Search

0.49	GO:0001867	complement activation, lectin pathway
0.40	GO:0007155	cell adhesion
0.39	GO:0032501	multicellular organismal process
0.39	GO:0048856	anatomical structure development
0.38	GO:0030198	extracellular matrix organization
0.38	GO:0052547	regulation of peptidase activity
0.38	GO:0030154	cell differentiation
0.38	GO:0045861	negative regulation of proteolysis
0.38	GO:0051346	negative regulation of hydrolase activity
0.37	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway

0.64	GO:0005201	extracellular matrix structural constituent
0.48	GO:0005537	mannose binding
0.38	GO:0004867	serine-type endopeptidase inhibitor activity
0.36	GO:0005515	protein binding
0.35	GO:0001540	amyloid-beta binding
0.35	GO:0042302	structural constituent of cuticle
0.35	GO:0008201	heparin binding
0.34	GO:0005509	calcium ion binding
0.33	GO:0044877	macromolecular complex binding
0.33	GO:0004838	L-tyrosine:2-oxoglutarate aminotransferase activity

0.67	GO:0005581	collagen trimer
0.56	GO:0044420	extracellular matrix component
0.53	GO:0005578	proteinaceous extracellular matrix
0.37	GO:0005615	extracellular space
0.36	GO:0099081	supramolecular polymer
0.34	GO:0031594	neuromuscular junction
0.33	GO:0005618	cell wall
0.33	GO:0005887	integral component of plasma membrane
0.33	GO:0005783	endoplasmic reticulum
0.32	GO:0019867	outer membrane

0.33

EC:2.6.1.5

GO:0004838

tr|T1ERS1|T1ERS1_HELRO
Uncharacterized protein
Search

tr|T1ERS2|T1ERS2_HELRO
Uncharacterized protein
Search

tr|T1ERS3|T1ERS3_HELRO
Uncharacterized protein
Search

0.53	GO:0007219	Notch signaling pathway
0.49	GO:0030154	cell differentiation
0.48	GO:0007275	multicellular organism development
0.47	GO:0050793	regulation of developmental process
0.44	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.42	GO:0060255	regulation of macromolecule metabolic process
0.42	GO:0080090	regulation of primary metabolic process
0.42	GO:0031323	regulation of cellular metabolic process
0.42	GO:0051171	regulation of nitrogen compound metabolic process
0.41	GO:0009889	regulation of biosynthetic process

0.69	GO:0005509	calcium ion binding
0.45	GO:0004872	receptor activity
0.36	GO:0030414	peptidase inhibitor activity
0.35	GO:0008270	zinc ion binding
0.35	GO:0030246	carbohydrate binding
0.33	GO:0004871	signal transducer activity

0.38	GO:0098858	actin-based cell projection
0.38	GO:0005911	cell-cell junction
0.38	GO:0005886	plasma membrane
0.37	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0030027	lamellipodium
0.36	GO:0033166	hyaline layer
0.36	GO:0043234	protein complex
0.35	GO:0005912	adherens junction
0.35	GO:0005634	nucleus
0.35	GO:0044420	extracellular matrix component

tr|T1ERS4|T1ERS4_HELRO
Uncharacterized protein
Search

0.38	GO:0003333	amino acid transmembrane transport
0.35	GO:0005980	glycogen catabolic process
0.35	GO:0005978	glycogen biosynthetic process
0.34	GO:0006914	autophagy
0.33	GO:0007009	plasma membrane organization
0.33	GO:0006338	chromatin remodeling
0.33	GO:0006468	protein phosphorylation
0.33	GO:0051607	defense response to virus
0.32	GO:0035023	regulation of Rho protein signal transduction
0.32	GO:0065009	regulation of molecular function

0.38	GO:0015171	amino acid transmembrane transporter activity
0.36	GO:0004135	amylo-alpha-1,6-glucosidase activity
0.35	GO:0004134	4-alpha-glucanotransferase activity
0.33	GO:0008641	ubiquitin-like modifier activating enzyme activity
0.33	GO:0004674	protein serine/threonine kinase activity
0.33	GO:0003676	nucleic acid binding
0.33	GO:0003682	chromatin binding
0.33	GO:0003779	actin binding
0.32	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.32	GO:0046872	metal ion binding

0.33	GO:0016586	RSC-type complex
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.36

EC:3.2.1.33

GO:0004135

tr|T1ERS5|T1ERS5_HELRO
Uncharacterized protein
Search

tr|T1ERS6|T1ERS6_HELRO
Uncharacterized protein
Search

0.77	GO:0035725	sodium ion transmembrane transport
0.38	GO:0007624	ultradian rhythm
0.38	GO:0030421	defecation
0.37	GO:0010447	response to acidic pH

0.81

GO:0005272

sodium channel activity

0.36	GO:0031965	nuclear membrane
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1ERS7|T1ERS7_HELRO
Uncharacterized protein
Search

tr|T1ERS8|T1ERS8_HELRO
Uncharacterized protein
Search

0.68	Putative tRNA 2'-phosphotransferase

0.81	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation
0.33	GO:0006508	proteolysis

0.57	GO:0016772	transferase activity, transferring phosphorus-containing groups
0.37	GO:0140101	catalytic activity, acting on a tRNA
0.34	GO:0003723	RNA binding
0.34	GO:0008236	serine-type peptidase activity

0.36	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.57

EC:2.7

GO:0016772

tr|T1ERS9|T1ERS9_HELRO
Uncharacterized protein
Search

tr|T1ERT0|T1ERT0_HELRO
Uncharacterized protein
Search

tr|T1ERT1|T1ERT1_HELRO
Uncharacterized protein
Search

0.45	GO:0007059	chromosome segregation
0.45	GO:0016579	protein deubiquitination
0.44	GO:0006511	ubiquitin-dependent protein catabolic process
0.43	GO:0051301	cell division
0.37	GO:0006468	protein phosphorylation
0.37	GO:0006413	translational initiation
0.36	GO:0007234	osmosensory signaling via phosphorelay pathway
0.36	GO:0060255	regulation of macromolecule metabolic process
0.36	GO:0016567	protein ubiquitination
0.36	GO:0031150	sorocarp stalk development

0.46	GO:0008017	microtubule binding
0.46	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.43	GO:0003723	RNA binding
0.37	GO:0004672	protein kinase activity
0.37	GO:0004252	serine-type endopeptidase activity
0.36	GO:0004842	ubiquitin-protein transferase activity
0.36	GO:0140110	transcription regulator activity
0.36	GO:0009927	histidine phosphotransfer kinase activity
0.36	GO:0004721	phosphoprotein phosphatase activity
0.35	GO:0008270	zinc ion binding

0.49	GO:0005876	spindle microtubule
0.48	GO:0000940	condensed chromosome outer kinetochore
0.35	GO:0020011	apicoplast
0.35	GO:0005634	nucleus
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0005615	extracellular space
0.34	GO:0000785	chromatin
0.34	GO:0005829	cytosol
0.33	GO:1904949	ATPase complex
0.30	GO:0016020	membrane

0.37	EC:3.4.21	GO:0004252
0.36	KEGG:R03876	GO:0004842

tr|T1ERT2|T1ERT2_HELRO
Uncharacterized protein
Search

tr|T1ERT3|T1ERT3_HELRO
Uncharacterized protein
Search

tr|T1ERT4|T1ERT4_HELRO
Uncharacterized protein
Search

tr|T1ERT5|T1ERT5_HELRO
Uncharacterized protein
Search

tr|T1ERT6|T1ERT6_HELRO
Uncharacterized protein
Search

tr|T1ERT7|T1ERT7_HELRO
Uncharacterized protein
Search

tr|T1ERT8|T1ERT8_HELRO
Uncharacterized protein
Search

tr|T1ERT9|T1ERT9_HELRO
Uncharacterized protein
Search

0.45	GO:0007166	cell surface receptor signaling pathway
0.44	GO:0007186	G-protein coupled receptor signaling pathway
0.41	GO:0016567	protein ubiquitination
0.41	GO:0060255	regulation of macromolecule metabolic process
0.40	GO:0080090	regulation of primary metabolic process
0.40	GO:0031323	regulation of cellular metabolic process
0.40	GO:0051171	regulation of nitrogen compound metabolic process
0.39	GO:0009889	regulation of biosynthetic process
0.39	GO:0009057	macromolecule catabolic process
0.38	GO:0009896	positive regulation of catabolic process

0.45	GO:0004930	G-protein coupled receptor activity
0.41	GO:0046872	metal ion binding
0.41	GO:0004842	ubiquitin-protein transferase activity
0.39	GO:0008061	chitin binding
0.39	GO:0031624	ubiquitin conjugating enzyme binding
0.38	GO:0061659	ubiquitin-like protein ligase activity
0.37	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity
0.37	GO:0019992	diacylglycerol binding
0.37	GO:0003677	DNA binding
0.36	GO:0003682	chromatin binding

0.41	GO:0005634	nucleus
0.38	GO:0000151	ubiquitin ligase complex
0.36	GO:0005576	extracellular region
0.35	GO:0019028	viral capsid
0.33	GO:0005737	cytoplasm
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.37	EC:2.7.11	GO:0004694
0.41	KEGG:R03876	GO:0004842

tr|T1ERU0|T1ERU0_HELRO
Uncharacterized protein
Search

tr|T1ERU1|T1ERU1_HELRO
Uncharacterized protein
Search

tr|T1ERU2|T1ERU2_HELRO
Uncharacterized protein
Search

tr|T1ERU3|T1ERU3_HELRO
Uncharacterized protein
Search

tr|T1ERU4|T1ERU4_HELRO
Uncharacterized protein
Search

0.55	GO:0007165	signal transduction
0.55	GO:0034220	ion transmembrane transport
0.40	GO:0043412	macromolecule modification
0.39	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.38	GO:0080090	regulation of primary metabolic process
0.38	GO:0051171	regulation of nitrogen compound metabolic process
0.38	GO:0010468	regulation of gene expression
0.38	GO:0044267	cellular protein metabolic process
0.37	GO:0031158	negative regulation of aggregate size involved in sorocarp development
0.37	GO:0048856	anatomical structure development

0.67	GO:0005230	extracellular ligand-gated ion channel activity
0.63	GO:0004888	transmembrane signaling receptor activity
0.39	GO:0140096	catalytic activity, acting on a protein
0.38	GO:0140110	transcription regulator activity
0.37	GO:0016791	phosphatase activity
0.37	GO:0008270	zinc ion binding
0.37	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.37	GO:0043565	sequence-specific DNA binding
0.36	GO:0016301	kinase activity
0.36	GO:0045182	translation regulator activity

0.49	GO:0005886	plasma membrane
0.38	GO:0005634	nucleus
0.38	GO:1902711	GABA-A receptor complex
0.35	GO:0005667	transcription factor complex
0.33	GO:0005739	mitochondrion
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

0.37

EC:3.1.3 EC:3.1.3.41

GO:0016791

tr|T1ERU5|T1ERU5_HELRO
Uncharacterized protein
Search

tr|T1ERU6|T1ERU6_HELRO
Uncharacterized protein
Search

0.36	GO:0045167	asymmetric protein localization involved in cell fate determination
0.36	GO:0016360	sensory organ precursor cell fate determination
0.36	GO:0035152	regulation of tube architecture, open tracheal system
0.36	GO:0046716	muscle cell cellular homeostasis
0.36	GO:0045746	negative regulation of Notch signaling pathway
0.33	GO:0006508	proteolysis

0.50	GO:0005509	calcium ion binding
0.36	GO:0005112	Notch binding
0.34	GO:0004252	serine-type endopeptidase activity

0.36	GO:0031901	early endosome membrane
0.35	GO:0016324	apical plasma membrane
0.34	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0004252

tr|T1ERU7|T1ERU7_HELRO
Uncharacterized protein
Search

0.38	GO:0038084	vascular endothelial growth factor signaling pathway
0.38	GO:0071526	semaphorin-plexin signaling pathway
0.37	GO:0042953	lipoprotein transport
0.37	GO:0001525	angiogenesis
0.37	GO:0007411	axon guidance
0.36	GO:0006898	receptor-mediated endocytosis

0.41	GO:0005509	calcium ion binding
0.38	GO:0005021	vascular endothelial growth factor-activated receptor activity
0.38	GO:0017154	semaphorin receptor activity
0.37	GO:0042803	protein homodimerization activity

0.47	GO:0043196	varicosity
0.42	GO:0045202	synapse
0.38	GO:0005903	brush border
0.38	GO:0016324	apical plasma membrane
0.38	GO:0030139	endocytic vesicle
0.38	GO:0070062	extracellular exosome
0.38	GO:0005905	clathrin-coated pit
0.37	GO:0005768	endosome
0.36	GO:0005794	Golgi apparatus
0.36	GO:0005783	endoplasmic reticulum

tr|T1ERU8|T1ERU8_HELRO
Uncharacterized protein
Search

0.46	GO:0060255	regulation of macromolecule metabolic process
0.46	GO:0051568	histone H3-K4 methylation
0.45	GO:0051171	regulation of nitrogen compound metabolic process
0.45	GO:0080090	regulation of primary metabolic process
0.45	GO:0031326	regulation of cellular biosynthetic process
0.42	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway
0.41	GO:0048519	negative regulation of biological process
0.41	GO:0043627	response to estrogen
0.41	GO:0031325	positive regulation of cellular metabolic process
0.40	GO:0009891	positive regulation of biosynthetic process

0.50	GO:0003712	transcription cofactor activity
0.46	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.42	GO:0003676	nucleic acid binding
0.41	GO:0005515	protein binding
0.41	GO:0046872	metal ion binding
0.40	GO:0004672	protein kinase activity
0.38	GO:0030554	adenyl nucleotide binding
0.38	GO:0097367	carbohydrate derivative binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0008144	drug binding

0.51	GO:0005634	nucleus
0.45	GO:0070013	intracellular organelle lumen
0.44	GO:0034708	methyltransferase complex
0.44	GO:0044446	intracellular organelle part
0.40	GO:0005856	cytoskeleton
0.39	GO:0031410	cytoplasmic vesicle
0.39	GO:0043234	protein complex
0.39	GO:0099512	supramolecular fiber
0.38	GO:0012505	endomembrane system
0.37	GO:0031248	protein acetyltransferase complex

0.34	EC:2.7.7.7	GO:0003887
0.36	KEGG:R03876	GO:0004842

tr|T1ERU9|T1ERU9_HELRO
Uncharacterized protein
Search

tr|T1ERV0|T1ERV0_HELRO
Uncharacterized protein
Search

tr|T1ERV1|T1ERV1_HELRO
Uncharacterized protein
Search

tr|T1ERV2|T1ERV2_HELRO
Uncharacterized protein
Search

tr|T1ERV3|T1ERV3_HELRO
Uncharacterized protein
Search

0.53	GO:0006914	autophagy
0.49	GO:0032049	cardiolipin biosynthetic process
0.41	GO:0036211	protein modification process
0.40	GO:0016569	covalent chromatin modification
0.39	GO:0044267	cellular protein metabolic process
0.38	GO:0048102	autophagic cell death
0.38	GO:0071423	malate transmembrane transport
0.38	GO:0043414	macromolecule methylation
0.38	GO:0065007	biological regulation
0.37	GO:0006189	'de novo' IMP biosynthetic process

0.49	GO:0008444	CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity
0.41	GO:0140096	catalytic activity, acting on a protein
0.41	GO:0016278	lysine N-methyltransferase activity
0.39	GO:0008270	zinc ion binding
0.38	GO:0015140	malate transmembrane transporter activity
0.38	GO:0004642	phosphoribosylformylglycinamidine synthase activity
0.37	GO:0003721	telomerase RNA reverse transcriptase activity
0.37	GO:0003676	nucleic acid binding
0.37	GO:0005509	calcium ion binding
0.37	GO:0003700	DNA binding transcription factor activity

0.40	GO:0043231	intracellular membrane-bounded organelle
0.38	GO:0005694	chromosome
0.38	GO:0098805	whole membrane
0.38	GO:0098588	bounding membrane of organelle
0.36	GO:0044444	cytoplasmic part
0.36	GO:0044446	intracellular organelle part
0.36	GO:0031461	cullin-RING ubiquitin ligase complex
0.35	GO:0048475	coated membrane
0.34	GO:0098796	membrane protein complex
0.30	GO:0016021	integral component of membrane

0.49	EC:2.7.8.5	GO:0008444
0.49	KEGG:R01801	GO:0008444

tr|T1ERV4|T1ERV4_HELRO
Uncharacterized protein
Search

tr|T1ERV5|T1ERV5_HELRO
Uncharacterized protein
Search

tr|T1ERV6|T1ERV6_HELRO
Uncharacterized protein
Search

tr|T1ERV7|T1ERV7_HELRO
Uncharacterized protein
Search

tr|T1ERV8|T1ERV8_HELRO
Uncharacterized protein
Search

tr|T1ERV9|T1ERV9_HELRO
Uncharacterized protein
Search

tr|T1ERW0|T1ERW0_HELRO
Uncharacterized protein
Search

tr|T1ERW1|T1ERW1_HELRO
Uncharacterized protein
Search

tr|T1ERW2|T1ERW2_HELRO
Uncharacterized protein
Search

tr|T1ERW3|T1ERW3_HELRO
Uncharacterized protein
Search

tr|T1ERW4|T1ERW4_HELRO
Uncharacterized protein
Search

tr|T1ERW5|T1ERW5_HELRO
Uncharacterized protein
Search

tr|T1ERW6|T1ERW6_HELRO
Uncharacterized protein
Search

0.33

GO:0035335

peptidyl-tyrosine dephosphorylation

0.35	GO:0005509	calcium ion binding
0.33	GO:0004725	protein tyrosine phosphatase activity

0.30

GO:0031224

intrinsic component of membrane

0.33

EC:3.1.3.48

GO:0004725

tr|T1ERW7|T1ERW7_HELRO
Uncharacterized protein
Search

tr|T1ERW8|T1ERW8_HELRO
Uncharacterized protein
Search

tr|T1ERW9|T1ERW9_HELRO
Uncharacterized protein
Search

tr|T1ERX0|T1ERX0_HELRO
Uncharacterized protein
Search

tr|T1ERX1|T1ERX1_HELRO
Uncharacterized protein
Search

tr|T1ERX2|T1ERX2_HELRO
Uncharacterized protein
Search

0.77	GO:0035725	sodium ion transmembrane transport
0.39	GO:0055078	sodium ion homeostasis
0.39	GO:0007624	ultradian rhythm
0.38	GO:0050891	multicellular organismal water homeostasis
0.38	GO:0030421	defecation
0.36	GO:0010447	response to acidic pH

0.81	GO:0005272	sodium channel activity
0.51	GO:0099094	ligand-gated cation channel activity
0.36	GO:0050699	WW domain binding

0.39	GO:0016324	apical plasma membrane
0.38	GO:0034706	sodium channel complex
0.37	GO:0031965	nuclear membrane
0.36	GO:0060170	ciliary membrane
0.36	GO:0005887	integral component of plasma membrane
0.36	GO:0070062	extracellular exosome
0.35	GO:0031514	motile cilium
0.32	GO:0005737	cytoplasm

tr|T1ERX3|T1ERX3_HELRO
Uncharacterized protein
Search

tr|T1ERX4|T1ERX4_HELRO
Uncharacterized protein
Search

tr|T1ERX5|T1ERX5_HELRO
Uncharacterized protein
Search

tr|T1ERX6|T1ERX6_HELRO
Uncharacterized protein
Search

0.81	Endoribonuclease XendoU

0.70	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.57	GO:0006955	immune response
0.56	GO:0006898	receptor-mediated endocytosis
0.49	GO:0007565	female pregnancy
0.42	GO:0006508	proteolysis
0.34	GO:0007034	vacuolar transport
0.34	GO:0010469	regulation of receptor activity
0.33	GO:1902476	chloride transmembrane transport
0.33	GO:0030001	metal ion transport

0.71	GO:0004521	endoribonuclease activity
0.61	GO:0005044	scavenger receptor activity
0.59	GO:0001871	pattern binding
0.54	GO:0030246	carbohydrate binding
0.44	GO:0017171	serine hydrolase activity
0.42	GO:0070011	peptidase activity, acting on L-amino acid peptides
0.42	GO:0003723	RNA binding
0.35	GO:0046872	metal ion binding
0.34	GO:0008083	growth factor activity
0.34	GO:0005254	chloride channel activity

0.37	GO:0005737	cytoplasm
0.36	GO:0005576	extracellular region
0.34	GO:0034707	chloride channel complex
0.32	GO:0005886	plasma membrane

tr|T1ERX7|T1ERX7_HELRO
Uncharacterized protein
Search

0.55

GO:0016539

intein-mediated protein splicing

tr|T1ERX8|T1ERX8_HELRO
Uncharacterized protein
Search

tr|T1ERX9|T1ERX9_HELRO
Uncharacterized protein
Search

tr|T1ERY0|T1ERY0_HELRO
Uncharacterized protein
Search

tr|T1ERY1|T1ERY1_HELRO
Uncharacterized protein
Search

tr|T1ERY2|T1ERY2_HELRO
Uncharacterized protein
Search

tr|T1ERY3|T1ERY3_HELRO
Uncharacterized protein
Search

tr|T1ERY4|T1ERY4_HELRO
Uncharacterized protein
Search

0.54	Integrin linked protein kinase

0.70	GO:0006414	translational elongation
0.41	GO:0071479	cellular response to ionizing radiation
0.34	GO:0007229	integrin-mediated signaling pathway
0.34	GO:0006419	alanyl-tRNA aminoacylation
0.34	GO:0019358	nicotinate nucleotide salvage
0.33	GO:0009435	NAD biosynthetic process
0.32	GO:0016310	phosphorylation

0.71	GO:0003746	translation elongation factor activity
0.40	GO:0045296	cadherin binding
0.36	GO:0003924	GTPase activity
0.36	GO:0032550	purine ribonucleoside binding
0.36	GO:0019001	guanyl nucleotide binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0004813	alanine-tRNA ligase activity
0.33	GO:0004516	nicotinate phosphoribosyltransferase activity
0.33	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity

0.84	GO:0005853	eukaryotic translation elongation factor 1 complex
0.41	GO:0001650	fibrillar center
0.38	GO:0005783	endoplasmic reticulum
0.38	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.34	EC:6.1.1.7	GO:0004813
0.33	KEGG:R01724	GO:0004516

tr|T1ERY5|T1ERY5_HELRO
Uncharacterized protein
Search

tr|T1ERY6|T1ERY6_HELRO
Uncharacterized protein
Search

tr|T1ERY7|T1ERY7_HELRO
Uncharacterized protein
Search

PDAP1

0.86	PDGFA associated protein 1 [Latimeria chalumnae]

0.51	GO:0016310	phosphorylation
0.40	GO:0055085	transmembrane transport

0.53	GO:0016301	kinase activity
0.37	GO:0003723	RNA binding

0.45	GO:0005829	cytosol
0.42	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

tr|T1ERY8|T1ERY8_HELRO
Uncharacterized protein
Search

MRPL21

0.80	Mitochondrial ribosomal protein L21

0.46	GO:0043043	peptide biosynthetic process
0.44	GO:0044267	cellular protein metabolic process
0.43	GO:0010467	gene expression
0.42	GO:0009059	macromolecule biosynthetic process
0.33	GO:0007165	signal transduction
0.33	GO:0055114	oxidation-reduction process

0.49	GO:0003735	structural constituent of ribosome
0.46	GO:0003723	RNA binding
0.34	GO:0003924	GTPase activity
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0019001	guanyl nucleotide binding
0.33	GO:0046872	metal ion binding
0.33	GO:0016491	oxidoreductase activity
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005840	ribosome
0.42	GO:0005759	mitochondrial matrix
0.30	GO:0016020	membrane

0.33

EC:1

GO:0016491

tr|T1ERY9|T1ERY9_HELRO
Uncharacterized protein
Search

0.65	GO:0006281	DNA repair
0.45	GO:0071494	cellular response to UV-C
0.42	GO:0071897	DNA biosynthetic process
0.37	GO:0009650	UV protection
0.37	GO:0010224	response to UV-B
0.36	GO:1904290	negative regulation of mitotic DNA damage checkpoint
0.35	GO:0009792	embryo development ending in birth or egg hatching
0.34	GO:0016567	protein ubiquitination
0.34	GO:0000003	reproduction
0.34	GO:0006260	DNA replication

0.70	GO:0003684	damaged DNA binding
0.43	GO:0003887	DNA-directed DNA polymerase activity
0.34	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0004252	serine-type endopeptidase activity
0.33	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.39	GO:0005654	nucleoplasm
0.39	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.43	EC:2.7.7.7	GO:0003887
0.34	KEGG:R03876	GO:0004842

tr|T1ERZ0|T1ERZ0_HELRO
Uncharacterized protein
Search

tr|T1ERZ1|T1ERZ1_HELRO
Uncharacterized protein
Search

tr|T1ERZ2|T1ERZ2_HELRO
Uncharacterized protein
Search

tr|T1ERZ3|T1ERZ3_HELRO
Uncharacterized protein
Search

tr|T1ERZ4|T1ERZ4_HELRO
Uncharacterized protein
Search

tr|T1ERZ5|T1ERZ5_HELRO
Uncharacterized protein
Search

tr|T1ERZ6|T1ERZ6_HELRO
Uncharacterized protein
Search

tr|T1ERZ7|T1ERZ7_HELRO
Uncharacterized protein
Search

tr|T1ERZ8|T1ERZ8_HELRO
Uncharacterized protein
Search

0.49	GO:0006402	mRNA catabolic process
0.41	GO:0016114	terpenoid biosynthetic process
0.41	GO:0036211	protein modification process
0.40	GO:0044267	cellular protein metabolic process
0.39	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.39	GO:0051171	regulation of nitrogen compound metabolic process
0.39	GO:0080090	regulation of primary metabolic process
0.39	GO:0016569	covalent chromatin modification
0.38	GO:0043414	macromolecule methylation
0.37	GO:0006796	phosphate-containing compound metabolic process

0.43	GO:0008661	1-deoxy-D-xylulose-5-phosphate synthase activity
0.40	GO:0140096	catalytic activity, acting on a protein
0.40	GO:0003700	DNA binding transcription factor activity
0.40	GO:0016278	lysine N-methyltransferase activity
0.37	GO:0016874	ligase activity
0.37	GO:0003677	DNA binding
0.37	GO:0046872	metal ion binding
0.37	GO:0016791	phosphatase activity
0.36	GO:0016772	transferase activity, transferring phosphorus-containing groups
0.36	GO:0043015	gamma-tubulin binding

0.52	GO:0030014	CCR4-NOT complex
0.38	GO:0005634	nucleus
0.36	GO:0043232	intracellular non-membrane-bounded organelle
0.35	GO:0005667	transcription factor complex
0.35	GO:0031201	SNARE complex
0.35	GO:0044446	intracellular organelle part
0.35	GO:0012505	endomembrane system
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0099023	tethering complex
0.34	GO:0032300	mismatch repair complex

0.43	EC:2.2.1.7	GO:0008661
0.43	KEGG:R05636	GO:0008661

tr|T1ERZ9|T1ERZ9_HELRO
Uncharacterized protein
Search

tr|T1ES00|T1ES00_HELRO
Uncharacterized protein
Search

0.48	GO:0031591	wybutosine biosynthetic process
0.42	GO:0006468	protein phosphorylation
0.38	GO:0055114	oxidation-reduction process
0.37	GO:0050794	regulation of cellular process
0.37	GO:0051641	cellular localization
0.37	GO:0018212	peptidyl-tyrosine modification
0.36	GO:0007018	microtubule-based movement
0.36	GO:0023052	signaling
0.36	GO:0007154	cell communication
0.36	GO:0006413	translational initiation

0.46	GO:0016706	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
0.43	GO:0000049	tRNA binding
0.42	GO:0004672	protein kinase activity
0.40	GO:0097367	carbohydrate derivative binding
0.39	GO:0017076	purine nucleotide binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0008144	drug binding
0.37	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.37	GO:0008843	endochitinase activity
0.37	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed

0.37	GO:0005933	cellular bud
0.37	GO:0030427	site of polarized growth
0.36	GO:0015630	microtubule cytoskeleton
0.36	GO:0044430	cytoskeletal part
0.35	GO:0000131	incipient cellular bud site
0.35	GO:0031362	anchored component of external side of plasma membrane
0.35	GO:0009277	fungal-type cell wall
0.35	GO:0005937	mating projection
0.35	GO:1902773	GTPase activator complex
0.35	GO:0120038	plasma membrane bounded cell projection part

0.46	EC:1.14.11	GO:0016706
0.35	KEGG:R02282	GO:0004358

tr|T1ES01|T1ES01_HELRO
Uncharacterized protein
Search

tr|T1ES02|T1ES02_HELRO
Uncharacterized protein
Search

0.78

GO:0006825

copper ion transport

0.85

GO:0016531

copper chaperone activity

0.79

GO:0005758

mitochondrial intermembrane space

tr|T1ES03|T1ES03_HELRO
Uncharacterized protein
Search

tr|T1ES04|T1ES04_HELRO
Uncharacterized protein
Search

tr|T1ES05|T1ES05_HELRO
Uncharacterized protein
Search

tr|T1ES06|T1ES06_HELRO
Uncharacterized protein
Search

tr|T1ES07|T1ES07_HELRO
Uncharacterized protein
Search

tr|T1ES08|T1ES08_HELRO
Uncharacterized protein
Search

0.13	RING-type E3 ubiquitin transferase

0.73	GO:0016567	protein ubiquitination
0.41	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.39	GO:0006511	ubiquitin-dependent protein catabolic process

0.74	GO:0004842	ubiquitin-protein transferase activity
0.51	GO:0046872	metal ion binding
0.41	GO:0031624	ubiquitin conjugating enzyme binding
0.39	GO:0061659	ubiquitin-like protein ligase activity
0.39	GO:0016874	ligase activity

0.39	GO:0000151	ubiquitin ligase complex
0.34	GO:0005737	cytoplasm

0.39	EC:6	GO:0016874
0.74	KEGG:R03876	GO:0004842

tr|T1ES09|T1ES09_HELRO
Uncharacterized protein
Search

tr|T1ES10|T1ES10_HELRO
Uncharacterized protein
Search

0.38

GO:1902600

hydrogen ion transmembrane transport

0.41

GO:0015299

solute:proton antiporter activity

0.30

GO:0016021

integral component of membrane

tr|T1ES11|T1ES11_HELRO
Uncharacterized protein
Search

0.42	GO:0035190	syncytial nuclear migration
0.42	GO:0009047	dosage compensation by hyperactivation of X chromosome
0.42	GO:0007279	pole cell formation
0.42	GO:0010526	negative regulation of transposition, RNA-mediated
0.42	GO:0035087	siRNA loading onto RISC involved in RNA interference
0.42	GO:0030423	targeting of mRNA for destruction involved in RNA interference
0.42	GO:0007367	segment polarity determination
0.41	GO:0070868	heterochromatin organization involved in chromatin silencing
0.41	GO:0045071	negative regulation of viral genome replication
0.41	GO:0033227	dsRNA transport

0.65	GO:0030246	carbohydrate binding
0.42	GO:0035197	siRNA binding
0.41	GO:0005515	protein binding
0.38	GO:0004521	endoribonuclease activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0003677	DNA binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0046872	metal ion binding

0.42	GO:0070578	RISC-loading complex
0.41	GO:0035068	micro-ribonucleoprotein complex
0.41	GO:0016442	RISC complex
0.38	GO:0005829	cytosol
0.36	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|T1ES12|T1ES12_HELRO
Uncharacterized protein
Search

tr|T1ES13|T1ES13_HELRO
Uncharacterized protein
Search

0.48	Dual specificity protein phosphatase, putative

0.72

GO:0006470

protein dephosphorylation

0.79	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.70	GO:0004725	protein tyrosine phosphatase activity

0.79

EC:3.1.3

GO:0008138

tr|T1ES14|T1ES14_HELRO
Uncharacterized protein
Search

0.56	GO:0005975	carbohydrate metabolic process
0.38	GO:0006351	transcription, DNA-templated
0.38	GO:0034968	histone lysine methylation
0.35	GO:0007264	small GTPase mediated signal transduction
0.35	GO:0006281	DNA repair
0.34	GO:0007018	microtubule-based movement
0.34	GO:0065009	regulation of molecular function
0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.39	GO:0016787	hydrolase activity
0.36	GO:0018024	histone-lysine N-methyltransferase activity
0.36	GO:0008017	microtubule binding
0.35	GO:0046872	metal ion binding
0.35	GO:0005085	guanyl-nucleotide exchange factor activity
0.34	GO:0003697	single-stranded DNA binding
0.34	GO:0003700	DNA binding transcription factor activity
0.33	GO:0016301	kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding

0.46	GO:0005618	cell wall
0.35	GO:0005634	nucleus
0.35	GO:0034708	methyltransferase complex
0.34	GO:0043233	organelle lumen
0.33	GO:0005840	ribosome
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.39

GO:0016787

tr|T1ES15|T1ES15_HELRO
Uncharacterized protein
Search

0.45	GO:0006325	chromatin organization
0.42	GO:0048208	COPII vesicle coating
0.41	GO:1903506	regulation of nucleic acid-templated transcription
0.41	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.41	GO:0010468	regulation of gene expression
0.41	GO:0018022	peptidyl-lysine methylation
0.40	GO:0006914	autophagy
0.39	GO:0006368	transcription elongation from RNA polymerase II promoter
0.38	GO:0015031	protein transport
0.37	GO:0009734	auxin-activated signaling pathway

0.55	GO:0008270	zinc ion binding
0.47	GO:0003676	nucleic acid binding
0.42	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.40	GO:0140110	transcription regulator activity
0.39	GO:0050825	ice binding
0.36	GO:0004594	pantothenate kinase activity
0.35	GO:0046983	protein dimerization activity
0.35	GO:0004386	helicase activity
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0032555	purine ribonucleotide binding

0.43	GO:0005634	nucleus
0.41	GO:1990234	transferase complex
0.41	GO:0043233	organelle lumen
0.40	GO:0044446	intracellular organelle part
0.39	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.39	GO:0005794	Golgi apparatus
0.39	GO:0098588	bounding membrane of organelle
0.39	GO:0005783	endoplasmic reticulum
0.36	GO:0043234	protein complex
0.35	GO:0005578	proteinaceous extracellular matrix

0.36

EC:2.7.1.33

GO:0004594

tr|T1ES16|T1ES16_HELRO
Uncharacterized protein
Search

0.47	GO:0055002	striated muscle cell development
0.40	GO:0046716	muscle cell cellular homeostasis
0.39	GO:0007626	locomotory behavior
0.39	GO:0030029	actin filament-based process
0.38	GO:0007010	cytoskeleton organization
0.36	GO:0010927	cellular component assembly involved in morphogenesis
0.36	GO:0007507	heart development
0.36	GO:0060271	cilium assembly
0.35	GO:0097435	supramolecular fiber organization

0.73	GO:0003779	actin binding
0.56	GO:0032403	protein complex binding
0.48	GO:0030506	ankyrin binding
0.35	GO:0042802	identical protein binding
0.34	GO:0030246	carbohydrate binding

0.46	GO:0042383	sarcolemma
0.41	GO:0005829	cytosol
0.36	GO:0016528	sarcoplasm
0.36	GO:0030018	Z disc
0.35	GO:0043034	costamere
0.34	GO:0005856	cytoskeleton
0.34	GO:0005925	focal adhesion
0.30	GO:0031224	intrinsic component of membrane

tr|T1ES17|T1ES17_HELRO
Uncharacterized protein
Search

tr|T1ES18|T1ES18_HELRO
Uncharacterized protein
Search

tr|T1ES19|T1ES19_HELRO
Uncharacterized protein
Search

tr|T1ES20|T1ES20_HELRO
Uncharacterized protein
Search

0.42	Calcium-binding EF-hand

0.41	GO:1990954	establishment of protein localization to meiotic spindle pole body
0.41	GO:0006468	protein phosphorylation
0.40	GO:0048767	root hair elongation
0.39	GO:0090307	mitotic spindle assembly
0.39	GO:0009409	response to cold

0.70	GO:0005509	calcium ion binding
0.41	GO:0004672	protein kinase activity
0.38	GO:0032559	adenyl ribonucleotide binding
0.38	GO:0008144	drug binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding

0.41	GO:0035840	old growing cell tip
0.40	GO:0035841	new growing cell tip
0.40	GO:0005739	mitochondrion
0.40	GO:0035974	meiotic spindle pole body
0.40	GO:0000935	division septum
0.40	GO:0044732	mitotic spindle pole body
0.39	GO:0043332	mating projection tip
0.36	GO:0005634	nucleus

tr|T1ES21|T1ES21_HELRO
Uncharacterized protein
Search

tr|T1ES22|T1ES22_HELRO
Uncharacterized protein
Search

tr|T1ES23|T1ES23_HELRO
Uncharacterized protein
Search

0.46	GO:0006325	chromatin organization
0.45	GO:0065004	protein-DNA complex assembly
0.45	GO:0006323	DNA packaging
0.42	GO:1901838	positive regulation of transcription of nucleolar large rRNA by RNA polymerase I
0.42	GO:0071364	cellular response to epidermal growth factor stimulus
0.41	GO:0006417	regulation of translation
0.41	GO:1990830	cellular response to leukemia inhibitory factor
0.40	GO:0006013	mannose metabolic process
0.40	GO:0001525	angiogenesis
0.40	GO:0036211	protein modification process

0.43	GO:0003676	nucleic acid binding
0.42	GO:0044547	DNA topoisomerase binding
0.42	GO:0042802	identical protein binding
0.41	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity
0.41	GO:0008022	protein C-terminus binding
0.40	GO:0003756	protein disulfide isomerase activity
0.40	GO:0017137	Rab GTPase binding
0.40	GO:0004559	alpha-mannosidase activity
0.40	GO:0018024	histone-lysine N-methyltransferase activity
0.39	GO:0032559	adenyl ribonucleotide binding

0.47	GO:0005634	nucleus
0.44	GO:0031974	membrane-enclosed lumen
0.41	GO:0044446	intracellular organelle part
0.40	GO:0030687	preribosome, large subunit precursor
0.40	GO:0036464	cytoplasmic ribonucleoprotein granule
0.39	GO:0034708	methyltransferase complex
0.39	GO:0005938	cell cortex
0.38	GO:0005783	endoplasmic reticulum
0.37	GO:0042025	host cell nucleus
0.30	GO:0016020	membrane

0.41	EC:2.7.11	GO:0004694
0.39	KEGG:R03876	GO:0004842

tr|T1ES24|T1ES24_HELRO
Uncharacterized protein
Search

tr|T1ES25|T1ES25_HELRO
Uncharacterized protein
Search

tr|T1ES26|T1ES26_HELRO
Uncharacterized protein
Search

tr|T1ES27|T1ES27_HELRO
Uncharacterized protein
Search

tr|T1ES28|T1ES28_HELRO
Uncharacterized protein
Search

tr|T1ES29|T1ES29_HELRO
Uncharacterized protein
Search

tr|T1ES30|T1ES30_HELRO
Uncharacterized protein
Search

tr|T1ES31|T1ES31_HELRO
Uncharacterized protein
Search

tr|T1ES32|T1ES32_HELRO
Uncharacterized protein
Search

tr|T1ES33|T1ES33_HELRO
Uncharacterized protein
Search

tr|T1ES34|T1ES34_HELRO
Uncharacterized protein
Search

tr|T1ES35|T1ES35_HELRO
Uncharacterized protein
Search

0.22	Serine/threonine-protein kinase TOR

0.63	GO:0006468	protein phosphorylation
0.50	GO:0031643	positive regulation of myelination
0.48	GO:0043588	skin development
0.48	GO:0048565	digestive tract development
0.47	GO:0032006	regulation of TOR signaling

0.70	GO:0004674	protein serine/threonine kinase activity
0.70	GO:0044877	macromolecular complex binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.70

GO:0004674

tr|T1ES36|T1ES36_HELRO
Uncharacterized protein
Search

tr|T1ES37|T1ES37_HELRO
Uncharacterized protein
Search

tr|T1ES38|T1ES38_HELRO
Uncharacterized protein
Search

tr|T1ES39|T1ES39_HELRO
Uncharacterized protein
Search

0.49	GO:0000055	ribosomal large subunit export from nucleus
0.48	GO:0042273	ribosomal large subunit biogenesis
0.45	GO:0030036	actin cytoskeleton organization
0.42	GO:0006325	chromatin organization
0.41	GO:0007018	microtubule-based movement
0.41	GO:0036211	protein modification process
0.40	GO:0006396	RNA processing
0.39	GO:0016310	phosphorylation
0.39	GO:0044267	cellular protein metabolic process
0.39	GO:0016072	rRNA metabolic process

0.42	GO:0043168	anion binding
0.42	GO:1901265	nucleoside phosphate binding
0.41	GO:0003777	microtubule motor activity
0.41	GO:0008017	microtubule binding
0.41	GO:0097367	carbohydrate derivative binding
0.41	GO:0008144	drug binding
0.41	GO:0036094	small molecule binding
0.40	GO:0004672	protein kinase activity
0.39	GO:0046872	metal ion binding
0.39	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding

0.45	GO:0005634	nucleus
0.41	GO:0030684	preribosome
0.41	GO:0070013	intracellular organelle lumen
0.39	GO:0043232	intracellular non-membrane-bounded organelle
0.39	GO:0044446	intracellular organelle part
0.37	GO:0043234	protein complex
0.37	GO:0005732	small nucleolar ribonucleoprotein complex
0.35	GO:1902494	catalytic complex
0.34	GO:0019013	viral nucleocapsid
0.34	GO:0005829	cytosol

0.36	EC:3.5.1.98	GO:0032041
0.35	KEGG:R03361	GO:0004430

tr|T1ES40|T1ES40_HELRO
Uncharacterized protein
Search

CDK5RAP1

0.82	LOW QUALITY PROTEIN: CDK5 regulatory subunit-associated protein 1

0.68	GO:0006400	tRNA modification
0.46	GO:0045903	positive regulation of translational fidelity
0.46	GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity
0.46	GO:0090646	mitochondrial tRNA processing
0.46	GO:0070131	positive regulation of mitochondrial translation
0.46	GO:1900864	mitochondrial RNA modification
0.43	GO:0070525	tRNA threonylcarbamoyladenosine metabolic process
0.34	GO:0046901	tetrahydrofolylpolyglutamate biosynthetic process
0.33	GO:0006508	proteolysis
0.33	GO:0055114	oxidation-reduction process

0.67	GO:0051539	4 iron, 4 sulfur cluster binding
0.51	GO:0016740	transferase activity
0.36	GO:0046982	protein heterodimerization activity
0.36	GO:0004386	helicase activity
0.35	GO:1901265	nucleoside phosphate binding
0.35	GO:0043168	anion binding
0.35	GO:0008234	cysteine-type peptidase activity
0.34	GO:0036094	small molecule binding
0.34	GO:0008144	drug binding
0.34	GO:0097367	carbohydrate derivative binding

0.48	GO:0005737	cytoplasm
0.37	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016020	membrane

0.51

GO:0016740

tr|T1ES41|T1ES41_HELRO
Uncharacterized protein
Search

tr|T1ES42|T1ES42_HELRO
Uncharacterized protein
Search

0.46	GO:0035082	axoneme assembly
0.41	GO:0006629	lipid metabolic process
0.40	GO:0006468	protein phosphorylation
0.39	GO:0065007	biological regulation
0.37	GO:0044265	cellular macromolecule catabolic process
0.37	GO:0016070	RNA metabolic process
0.37	GO:0006907	pinocytosis
0.37	GO:0051716	cellular response to stimulus
0.36	GO:0042254	ribosome biogenesis
0.36	GO:0010467	gene expression

0.40	GO:0004672	protein kinase activity
0.39	GO:0003700	DNA binding transcription factor activity
0.38	GO:0030554	adenyl nucleotide binding
0.38	GO:0097367	carbohydrate derivative binding
0.38	GO:0008144	drug binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0005515	protein binding
0.37	GO:0016787	hydrolase activity
0.37	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.37	GO:0098772	molecular function regulator

0.39	GO:0005634	nucleus
0.37	GO:0030688	preribosome, small subunit precursor
0.37	GO:0020008	rhoptry
0.36	GO:0019005	SCF ubiquitin ligase complex
0.35	GO:0000932	P-body
0.35	GO:0000178	exosome (RNase complex)
0.35	GO:0032300	mismatch repair complex
0.35	GO:0030117	membrane coat
0.34	GO:0005667	transcription factor complex
0.34	GO:0070013	intracellular organelle lumen

0.37	EC:3	GO:0016787
0.35	KEGG:R01801	GO:0008444

tr|T1ES43|T1ES43_HELRO
Uncharacterized protein
Search

0.60	GO:0005975	carbohydrate metabolic process
0.43	GO:0060051	negative regulation of protein glycosylation
0.36	GO:0007283	spermatogenesis
0.35	GO:0006486	protein glycosylation
0.35	GO:0030154	cell differentiation
0.34	GO:0006457	protein folding

0.69	GO:0016758	transferase activity, transferring hexosyl groups
0.36	GO:0140103	catalytic activity, acting on a glycoprotein
0.35	GO:0008194	UDP-glycosyltransferase activity
0.34	GO:0051082	unfolded protein binding
0.34	GO:0005509	calcium ion binding

0.41	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.40	GO:0098791	Golgi subcompartment
0.39	GO:0005783	endoplasmic reticulum
0.37	GO:0098588	bounding membrane of organelle
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.30	GO:0031224	intrinsic component of membrane

0.69

EC:2.4.1

GO:0016758

tr|T1ES44|T1ES44_HELRO
Uncharacterized protein
Search

tr|T1ES45|T1ES45_HELRO
Uncharacterized protein
Search

tr|T1ES46|T1ES46_HELRO
Uncharacterized protein
Search

0.72	GO:0007017	microtubule-based process
0.69	GO:0007010	cytoskeleton organization
0.58	GO:0051258	protein polymerization
0.56	GO:0097435	supramolecular fiber organization
0.44	GO:2000767	positive regulation of cytoplasmic translation
0.42	GO:1903047	mitotic cell cycle process
0.37	GO:0051661	maintenance of centrosome location
0.37	GO:0009794	regulation of mitotic cell cycle, embryonic
0.37	GO:0016048	detection of temperature stimulus
0.36	GO:0000819	sister chromatid segregation

0.68	GO:0003924	GTPase activity
0.67	GO:0005200	structural constituent of cytoskeleton
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0005515	protein binding
0.35	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.33	GO:0003677	DNA binding
0.32	GO:0003723	RNA binding

0.73	GO:0005874	microtubule
0.62	GO:0000930	gamma-tubulin complex
0.44	GO:0005822	inner plaque of spindle pole body
0.44	GO:0005824	outer plaque of spindle pole body
0.38	GO:0005634	nucleus
0.36	GO:0005813	centrosome
0.35	GO:0036064	ciliary basal body
0.35	GO:0000922	spindle pole
0.34	GO:0031021	interphase microtubule organizing center
0.34	GO:0045298	tubulin complex

0.35

EC:2.7.7.6

GO:0003899

tr|T1ES47|T1ES47_HELRO
Uncharacterized protein
Search

MRPL52

0.62	Mitochondrial ribosomal protein L52

0.81	GO:0032543	mitochondrial translation
0.36	GO:0006415	translational termination
0.36	GO:0006414	translational elongation
0.34	GO:0006508	proteolysis

0.64	GO:0003735	structural constituent of ribosome
0.36	GO:0004222	metalloendopeptidase activity
0.35	GO:0008270	zinc ion binding

0.81	GO:0005762	mitochondrial large ribosomal subunit
0.36	GO:0031966	mitochondrial membrane
0.36	GO:0019866	organelle inner membrane
0.36	GO:0031012	extracellular matrix
0.30	GO:0016021	integral component of membrane

0.36

EC:3.4.24

GO:0004222

tr|T1ES48|T1ES48_HELRO
Uncharacterized protein
Search

0.59	GO:0007018	microtubule-based movement
0.58	GO:0007088	regulation of mitotic nuclear division
0.43	GO:0023014	signal transduction by protein phosphorylation
0.43	GO:0009903	chloroplast avoidance movement
0.42	GO:0009904	chloroplast accumulation movement
0.42	GO:0000160	phosphorelay signal transduction system
0.40	GO:0042981	regulation of apoptotic process
0.40	GO:0007062	sister chromatid cohesion
0.40	GO:0030261	chromosome condensation
0.38	GO:0006260	DNA replication

0.59	GO:0003777	microtubule motor activity
0.59	GO:0008017	microtubule binding
0.47	GO:0032559	adenyl ribonucleotide binding
0.47	GO:0008144	drug binding
0.47	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0000155	phosphorelay sensor kinase activity
0.41	GO:0051015	actin filament binding
0.41	GO:0003676	nucleic acid binding

0.41	GO:0016459	myosin complex
0.38	GO:0005794	Golgi apparatus
0.38	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.43

EC:2.7.3

GO:0000155

tr|T1ES49|T1ES49_HELRO
Uncharacterized protein
Search

0.44	GO:0007018	microtubule-based movement
0.37	GO:0016925	protein sumoylation
0.37	GO:0010501	RNA secondary structure unwinding
0.37	GO:0006367	transcription initiation from RNA polymerase II promoter
0.36	GO:0006508	proteolysis
0.36	GO:0071804	cellular potassium ion transport
0.36	GO:0006470	protein dephosphorylation
0.35	GO:0065007	biological regulation
0.35	GO:0098662	inorganic cation transmembrane transport
0.34	GO:0023052	signaling

0.49	GO:0004386	helicase activity
0.45	GO:0003723	RNA binding
0.44	GO:0003777	microtubule motor activity
0.43	GO:0032559	adenyl ribonucleotide binding
0.42	GO:0008144	drug binding
0.42	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0046872	metal ion binding
0.38	GO:0140096	catalytic activity, acting on a protein
0.37	GO:0046332	SMAD binding
0.37	GO:0005249	voltage-gated potassium channel activity

0.37	GO:0008076	voltage-gated potassium channel complex
0.36	GO:0005730	nucleolus
0.33	GO:0005737	cytoplasm

0.35

EC:3.1.3 EC:3.1.3.41

GO:0016791

tr|T1ES50|T1ES50_HELRO
Uncharacterized protein
Search

tr|T1ES51|T1ES51_HELRO
Uncharacterized protein
Search

tr|T1ES52|T1ES52_HELRO
Uncharacterized protein
Search

tr|T1ES53|T1ES53_HELRO
Uncharacterized protein
Search

0.46	GO:0060255	regulation of macromolecule metabolic process
0.42	GO:0031323	regulation of cellular metabolic process
0.42	GO:0051171	regulation of nitrogen compound metabolic process
0.42	GO:0080090	regulation of primary metabolic process
0.42	GO:0009889	regulation of biosynthetic process
0.41	GO:0097659	nucleic acid-templated transcription
0.40	GO:0048106	establishment of thoracic bristle planar orientation
0.40	GO:0010467	gene expression
0.40	GO:0035321	maintenance of imaginal disc-derived wing hair orientation
0.40	GO:1900455	regulation of flocculation via cell wall protein-carbohydrate interaction

0.49	GO:0003682	chromatin binding
0.43	GO:0003676	nucleic acid binding
0.43	GO:0140110	transcription regulator activity
0.39	GO:0005515	protein binding
0.38	GO:0046872	metal ion binding
0.36	GO:0004651	polynucleotide 5'-phosphatase activity
0.36	GO:0140096	catalytic activity, acting on a protein
0.35	GO:0004874	aryl hydrocarbon receptor activity
0.35	GO:0016772	transferase activity, transferring phosphorus-containing groups
0.35	GO:0005267	potassium channel activity

0.44	GO:0005634	nucleus
0.38	GO:0070013	intracellular organelle lumen
0.37	GO:0005667	transcription factor complex
0.36	GO:0000428	DNA-directed RNA polymerase complex
0.36	GO:0044446	intracellular organelle part
0.36	GO:0031931	TORC1 complex
0.35	GO:0034751	aryl hydrocarbon receptor complex
0.35	GO:0032153	cell division site
0.34	GO:0005887	integral component of plasma membrane
0.34	GO:0030688	preribosome, small subunit precursor

0.36

EC:3.1.3.33

GO:0004651

tr|T1ES54|T1ES54_HELRO
Uncharacterized protein
Search

tr|T1ES55|T1ES55_HELRO
Uncharacterized protein
Search

tr|T1ES56|T1ES56_HELRO
Uncharacterized protein
Search

tr|T1ES57|T1ES57_HELRO
Uncharacterized protein
Search

tr|T1ES58|T1ES58_HELRO
Uncharacterized protein
Search

tr|T1ES59|T1ES59_HELRO
Uncharacterized protein
Search

tr|T1ES60|T1ES60_HELRO
Uncharacterized protein
Search

tr|T1ES61|T1ES61_HELRO
Uncharacterized protein
Search

tr|T1ES62|T1ES62_HELRO
Uncharacterized protein
Search

tr|T1ES63|T1ES63_HELRO
Uncharacterized protein
Search

tr|T1ES64|T1ES64_HELRO
Uncharacterized protein
Search

0.40	GO:0007155	cell adhesion
0.39	GO:0000226	microtubule cytoskeleton organization
0.38	GO:0070647	protein modification by small protein conjugation or removal
0.38	GO:0022402	cell cycle process
0.37	GO:0044085	cellular component biogenesis
0.37	GO:0065007	biological regulation
0.37	GO:0090304	nucleic acid metabolic process
0.36	GO:0034654	nucleobase-containing compound biosynthetic process
0.36	GO:0010467	gene expression
0.36	GO:0009059	macromolecule biosynthetic process

0.45	GO:0003723	RNA binding
0.42	GO:0005518	collagen binding
0.38	GO:0004842	ubiquitin-protein transferase activity
0.37	GO:0003677	DNA binding
0.37	GO:0003887	DNA-directed DNA polymerase activity
0.36	GO:0003700	DNA binding transcription factor activity
0.35	GO:0030554	adenyl nucleotide binding
0.35	GO:0017016	Ras GTPase binding
0.35	GO:0008144	drug binding
0.35	GO:0032555	purine ribonucleotide binding

0.40	GO:0005618	cell wall
0.39	GO:0005576	extracellular region
0.39	GO:0005634	nucleus
0.37	GO:0070013	intracellular organelle lumen
0.37	GO:0044446	intracellular organelle part
0.36	GO:0043232	intracellular non-membrane-bounded organelle
0.36	GO:0032991	macromolecular complex
0.35	GO:0005773	vacuole
0.34	GO:0098805	whole membrane
0.34	GO:0098588	bounding membrane of organelle

0.37	EC:2.7.7.7	GO:0003887
0.38	KEGG:R03876	GO:0004842

tr|T1ES65|T1ES65_HELRO
Uncharacterized protein
Search

tr|T1ES66|T1ES66_HELRO
Uncharacterized protein
Search

0.61

GO:0006508

proteolysis

0.74	GO:0004181	metallocarboxypeptidase activity
0.61	GO:0008270	zinc ion binding

0.74

EC:3.4.17

GO:0004181

tr|T1ES67|T1ES67_HELRO
Uncharacterized protein
Search

tr|T1ES68|T1ES68_HELRO
Uncharacterized protein
Search

0.80	GO:0017158	regulation of calcium ion-dependent exocytosis
0.51	GO:0006887	exocytosis
0.47	GO:0050708	regulation of protein secretion
0.46	GO:0090276	regulation of peptide hormone secretion
0.44	GO:0051640	organelle localization
0.44	GO:0099504	synaptic vesicle cycle
0.44	GO:0099003	vesicle-mediated transport in synapse
0.43	GO:0006906	vesicle fusion
0.43	GO:0099643	signal release from synapse
0.43	GO:0099531	presynaptic process involved in chemical synaptic transmission

0.52	GO:0005544	calcium-dependent phospholipid binding
0.44	GO:0019905	syntaxin binding
0.43	GO:0030276	clathrin binding
0.40	GO:0005509	calcium ion binding
0.40	GO:0042802	identical protein binding
0.40	GO:0001786	phosphatidylserine binding
0.39	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.39	GO:0048487	beta-tubulin binding
0.39	GO:0031369	translation initiation factor binding
0.38	GO:0031625	ubiquitin protein ligase binding

0.43	GO:0098793	presynapse
0.40	GO:0031410	cytoplasmic vesicle
0.39	GO:0001891	phagocytic cup
0.39	GO:0012505	endomembrane system
0.38	GO:0005764	lysosome
0.38	GO:0043005	neuron projection
0.36	GO:0016324	apical plasma membrane
0.36	GO:0005887	integral component of plasma membrane

tr|T1ES69|T1ES69_HELRO
Uncharacterized protein
Search

0.51

GO:0003676

nucleic acid binding

tr|T1ES70|T1ES70_HELRO
Uncharacterized protein
Search

0.54	Carbonate dehydratase, eukaryotic-type (Fragment)

0.60

GO:0006730

one-carbon metabolic process

0.68	GO:0004089	carbonate dehydratase activity
0.53	GO:0008270	zinc ion binding

0.43	GO:0005576	extracellular region
0.41	GO:0042597	periplasmic space
0.30	GO:0031224	intrinsic component of membrane

0.68

EC:4.2.1.1

GO:0004089

tr|T1ES71|T1ES71_HELRO
Uncharacterized protein
Search

tr|T1ES72|T1ES72_HELRO
Uncharacterized protein
Search

tr|T1ES73|T1ES73_HELRO
Uncharacterized protein
Search

tr|T1ES74|T1ES74_HELRO
Uncharacterized protein
Search

tr|T1ES75|T1ES75_HELRO
Uncharacterized protein
Search

tr|T1ES76|T1ES76_HELRO
Uncharacterized protein
Search

tr|T1ES77|T1ES77_HELRO
Uncharacterized protein
Search

tr|T1ES78|T1ES78_HELRO
Uncharacterized protein
Search

tr|T1ES79|T1ES79_HELRO
Uncharacterized protein
Search

tr|T1ES80|T1ES80_HELRO
Uncharacterized protein
Search

tr|T1ES81|T1ES81_HELRO
Uncharacterized protein
Search

tr|T1ES82|T1ES82_HELRO
Uncharacterized protein
Search

0.65	GO:0007275	multicellular organism development
0.53	GO:1903506	regulation of nucleic acid-templated transcription
0.53	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.52	GO:0010468	regulation of gene expression
0.41	GO:2000648	positive regulation of stem cell proliferation
0.41	GO:2000179	positive regulation of neural precursor cell proliferation
0.39	GO:0010720	positive regulation of cell development
0.39	GO:0051962	positive regulation of nervous system development
0.39	GO:0060322	head development
0.38	GO:0030154	cell differentiation

0.59

GO:0043565

sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|T1ES83|T1ES83_HELRO
Uncharacterized protein
Search

tr|T1ES84|T1ES84_HELRO
Uncharacterized protein
Search

0.47	GO:0009405	pathogenesis
0.42	GO:0031103	axon regeneration
0.40	GO:0030900	forebrain development
0.40	GO:0009409	response to cold
0.39	GO:0006796	phosphate-containing compound metabolic process
0.39	GO:0036211	protein modification process
0.38	GO:0044267	cellular protein metabolic process
0.38	GO:0044085	cellular component biogenesis
0.38	GO:0016072	rRNA metabolic process
0.38	GO:0006333	chromatin assembly or disassembly

0.40	GO:0015299	solute:proton antiporter activity
0.39	GO:0008641	ubiquitin-like modifier activating enzyme activity
0.39	GO:0016301	kinase activity
0.39	GO:1901265	nucleoside phosphate binding
0.39	GO:0005509	calcium ion binding
0.39	GO:0140096	catalytic activity, acting on a protein
0.39	GO:0097367	carbohydrate derivative binding
0.39	GO:0008144	drug binding
0.38	GO:0036094	small molecule binding
0.38	GO:0043168	anion binding

0.40	GO:0005634	nucleus
0.38	GO:0005750	mitochondrial respiratory chain complex III
0.37	GO:0032040	small-subunit processome
0.36	GO:0043233	organelle lumen
0.35	GO:0005886	plasma membrane
0.35	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.37

EC:4.6

GO:0016849

tr|T1ES85|T1ES85_HELRO
Uncharacterized protein
Search

0.47	GO:0055074	calcium ion homeostasis
0.45	GO:0072027	connecting tubule development
0.44	GO:0072221	metanephric distal convoluted tubule development
0.44	GO:0035502	metanephric part of ureteric bud development
0.44	GO:0072205	metanephric collecting duct development
0.43	GO:1900271	regulation of long-term synaptic potentiation
0.43	GO:0007614	short-term memory
0.43	GO:0010842	retina layer formation
0.43	GO:0007616	long-term memory
0.42	GO:0007626	locomotory behavior

0.70	GO:0005509	calcium ion binding
0.40	GO:0043531	ADP binding
0.38	GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor
0.38	GO:0008270	zinc ion binding
0.36	GO:0004601	peroxidase activity

0.42	GO:0043025	neuronal cell body
0.42	GO:0030425	dendrite
0.41	GO:0030424	axon
0.40	GO:0045202	synapse
0.39	GO:0005829	cytosol
0.37	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.38	EC:1.6.3	GO:0050664
0.36	KEGG:R03532	GO:0004601

tr|T1ES86|T1ES86_HELRO
Uncharacterized protein
Search

tr|T1ES87|T1ES87_HELRO
Uncharacterized protein
Search

tr|T1ES88|T1ES88_HELRO
Uncharacterized protein
Search

tr|T1ES89|T1ES89_HELRO
Uncharacterized protein
Search

tr|T1ES90|T1ES90_HELRO
Uncharacterized protein
Search

tr|T1ES91|T1ES91_HELRO
Uncharacterized protein
Search

tr|T1ES92|T1ES92_HELRO
Uncharacterized protein
Search

tr|T1ES93|T1ES93_HELRO
Uncharacterized protein
Search

ALG14

0.47	UDP-N-acetylglucosamine transferase subunit ALG

0.83	GO:0006488	dolichol-linked oligosaccharide biosynthetic process
0.34	GO:0030150	protein import into mitochondrial matrix
0.34	GO:0006508	proteolysis
0.33	GO:0031032	actomyosin structure organization
0.33	GO:0009116	nucleoside metabolic process
0.33	GO:0043043	peptide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0016310	phosphorylation
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process

0.44	GO:0016740	transferase activity
0.36	GO:0008234	cysteine-type peptidase activity
0.33	GO:0005516	calmodulin binding
0.33	GO:0003735	structural constituent of ribosome
0.33	GO:0003779	actin binding

0.43	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0031965	nuclear membrane
0.34	GO:0005742	mitochondrial outer membrane translocase complex
0.33	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.44

GO:0016740

tr|T1ES94|T1ES94_HELRO
Uncharacterized protein
Search

0.63	GO:0098869	cellular oxidant detoxification
0.49	GO:0055114	oxidation-reduction process
0.37	GO:0009405	pathogenesis
0.36	GO:0000256	allantoin catabolic process
0.35	GO:0007018	microtubule-based movement
0.35	GO:0010501	RNA secondary structure unwinding
0.34	GO:0035023	regulation of Rho protein signal transduction
0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression

0.70	GO:0004096	catalase activity
0.58	GO:0020037	heme binding
0.39	GO:0032550	purine ribonucleoside binding
0.39	GO:0032561	guanyl ribonucleotide binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0030554	adenyl nucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0004037	allantoicase activity
0.36	GO:0004872	receptor activity
0.35	GO:0003777	microtubule motor activity

0.36	GO:0030286	dynein complex
0.34	GO:0005730	nucleolus
0.33	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.70	EC:1.11.1.6	GO:0004096
0.36	KEGG:R02422	GO:0004037

tr|T1ES95|T1ES95_HELRO
Uncharacterized protein
Search

tr|T1ES96|T1ES96_HELRO
Uncharacterized protein
Search

tr|T1ES97|T1ES97_HELRO
Uncharacterized protein
Search

tr|T1ES98|T1ES98_HELRO
Uncharacterized protein
Search

SMTNL2

0.74	Putative calponin similarity domain protein (Fragment)

0.58	GO:0045907	positive regulation of vasoconstriction
0.58	GO:0014823	response to activity
0.57	GO:0048644	muscle organ morphogenesis
0.57	GO:0097756	negative regulation of blood vessel diameter
0.55	GO:0018105	peptidyl-serine phosphorylation
0.50	GO:0045892	negative regulation of transcription, DNA-templated
0.49	GO:0042493	response to drug
0.43	GO:0035335	peptidyl-tyrosine dephosphorylation

0.62	GO:0051401	CH domain binding
0.58	GO:0008092	cytoskeletal protein binding
0.57	GO:0097718	disordered domain specific binding
0.57	GO:0008157	protein phosphatase 1 binding
0.57	GO:0043621	protein self-association
0.54	GO:0005516	calmodulin binding
0.49	GO:0005509	calcium ion binding
0.43	GO:0004725	protein tyrosine phosphatase activity
0.43	GO:0001883	purine nucleoside binding
0.43	GO:0019001	guanyl nucleotide binding

0.58	GO:0031430	M band
0.56	GO:0031674	I band
0.48	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

0.43

EC:3.1.3.48

GO:0004725

tr|T1ES99|T1ES99_HELRO
Uncharacterized protein
Search

0.41	GO:0006281	DNA repair
0.40	GO:0001522	pseudouridine synthesis
0.39	GO:1903506	regulation of nucleic acid-templated transcription
0.39	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.39	GO:0010468	regulation of gene expression
0.38	GO:0016567	protein ubiquitination

0.44	GO:0003684	damaged DNA binding
0.40	GO:0003700	DNA binding transcription factor activity
0.40	GO:0009982	pseudouridine synthase activity
0.38	GO:0004842	ubiquitin-protein transferase activity
0.37	GO:0043565	sequence-specific DNA binding
0.37	GO:0008270	zinc ion binding
0.37	GO:0003723	RNA binding
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0016020

membrane

0.40	EC:5.4.99.12	GO:0009982
0.38	KEGG:R03876	GO:0004842

tr|T1ESA0|T1ESA0_HELRO
Uncharacterized protein
Search

tr|T1ESA1|T1ESA1_HELRO
Uncharacterized protein
Search

tr|T1ESA2|T1ESA2_HELRO
Uncharacterized protein
Search

tr|T1ESA3|T1ESA3_HELRO
Uncharacterized protein
Search

0.70	INO80 complex subunit E (Fragment)

0.78	GO:0006338	chromatin remodeling
0.38	GO:0007420	brain development
0.37	GO:0006310	DNA recombination
0.37	GO:0006281	DNA repair
0.36	GO:0006351	transcription, DNA-templated
0.35	GO:0016579	protein deubiquitination
0.35	GO:1903506	regulation of nucleic acid-templated transcription
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression

0.34

GO:0005515

protein binding

0.80	GO:0031011	Ino80 complex
0.57	GO:0005730	nucleolus
0.35	GO:0005654	nucleoplasm

tr|T1ESA4|T1ESA4_HELRO
Derlin
Search

DERL2

0.64

Derlin

0.54	GO:1904153	negative regulation of retrograde protein transport, ER to cytosol
0.52	GO:0030970	retrograde protein transport, ER to cytosol
0.52	GO:0001967	suckling behavior
0.51	GO:0030968	endoplasmic reticulum unfolded protein response
0.51	GO:0030433	ubiquitin-dependent ERAD pathway
0.50	GO:0030307	positive regulation of cell growth
0.49	GO:0008284	positive regulation of cell proliferation
0.37	GO:0018279	protein N-linked glycosylation via asparagine
0.35	GO:1904380	endoplasmic reticulum mannose trimming

0.33

GO:0005515

protein binding

0.72	GO:0005789	endoplasmic reticulum membrane
0.51	GO:0005791	rough endoplasmic reticulum
0.49	GO:0048500	signal recognition particle
0.49	GO:0005770	late endosome
0.49	GO:0005769	early endosome
0.46	GO:0098588	bounding membrane of organelle
0.43	GO:0098796	membrane protein complex
0.35	GO:0044322	endoplasmic reticulum quality control compartment
0.30	GO:0016021	integral component of membrane

tr|T1ESA5|T1ESA5_HELRO
Uncharacterized protein
Search

tr|T1ESA6|T1ESA6_HELRO
Uncharacterized protein
Search

0.57	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.46	GO:0006278	RNA-dependent DNA biosynthetic process
0.44	GO:0044806	G-quadruplex DNA unwinding
0.43	GO:0032211	negative regulation of telomere maintenance via telomerase
0.43	GO:0051974	negative regulation of telomerase activity
0.42	GO:0000002	mitochondrial genome maintenance
0.39	GO:0032508	DNA duplex unwinding
0.38	GO:0006260	DNA replication
0.37	GO:0035725	sodium ion transmembrane transport
0.36	GO:0007229	integrin-mediated signaling pathway

0.60	GO:0004386	helicase activity
0.58	GO:0004519	endonuclease activity
0.46	GO:0003964	RNA-directed DNA polymerase activity
0.44	GO:0010521	telomerase inhibitor activity
0.39	GO:0008094	DNA-dependent ATPase activity
0.38	GO:0005272	sodium channel activity
0.35	GO:0046872	metal ion binding

0.40	GO:0005657	replication fork
0.37	GO:0005634	nucleus
0.37	GO:0005739	mitochondrion
0.37	GO:0048786	presynaptic active zone
0.30	GO:0031224	intrinsic component of membrane

0.46