Queries 3001 to 4000

GO:0004674

tr|T1ELK7|T1ELK7_HELRO
Uncharacterized protein
Search

ERCC3

0.40	General transcription and DNA repair factor IIH helicase subunit XPB

0.79	GO:0006367	transcription initiation from RNA polymerase II promoter
0.73	GO:0006289	nucleotide-excision repair
0.70	GO:0032392	DNA geometric change
0.48	GO:0009411	response to UV
0.44	GO:1903025	regulation of RNA polymerase II regulatory region sequence-specific DNA binding
0.44	GO:0035315	hair cell differentiation
0.42	GO:1901990	regulation of mitotic cell cycle phase transition
0.42	GO:0006915	apoptotic process
0.41	GO:0040008	regulation of growth
0.41	GO:0043065	positive regulation of apoptotic process

0.72	GO:0004003	ATP-dependent DNA helicase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.55	GO:0003677	DNA binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0047485	protein N-terminus binding
0.44	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity
0.43	GO:0008022	protein C-terminus binding
0.43	GO:0043138	3'-5' DNA helicase activity
0.40	GO:0008134	transcription factor binding

0.48	GO:0005675	holo TFIIH complex
0.42	GO:0005669	transcription factor TFIID complex
0.41	GO:0031390	Ctf18 RFC-like complex
0.35	GO:0000439	core TFIIH complex
0.34	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.44

EC:2.7.11.23

GO:0008353

tr|T1ELK8|T1ELK8_HELRO
Uncharacterized protein
Search

0.57	AP complex subunit sigma

0.69	GO:0006886	intracellular protein transport
0.68	GO:0016192	vesicle-mediated transport
0.41	GO:0042051	compound eye photoreceptor development
0.40	GO:0007411	axon guidance
0.34	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.33	GO:0006468	protein phosphorylation

0.70	GO:0008565	protein transporter activity
0.35	GO:0030276	clathrin binding
0.33	GO:0005509	calcium ion binding
0.33	GO:0004672	protein kinase activity

0.75	GO:0030117	membrane coat
0.40	GO:0012510	trans-Golgi network transport vesicle membrane
0.38	GO:0044431	Golgi apparatus part
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1ELK9|T1ELK9_HELRO
Uncharacterized protein
Search

0.24	Nucleoredoxin

0.68	GO:0045454	cell redox homeostasis
0.45	GO:0031397	negative regulation of protein ubiquitination
0.44	GO:0030178	negative regulation of Wnt signaling pathway
0.44	GO:0098869	cellular oxidant detoxification
0.43	GO:0072358	cardiovascular system development
0.37	GO:0080092	regulation of pollen tube growth
0.37	GO:0010183	pollen tube guidance
0.37	GO:0030154	cell differentiation
0.37	GO:0009932	cell tip growth
0.36	GO:0046686	response to cadmium ion

0.48	GO:0004791	thioredoxin-disulfide reductase activity
0.38	GO:0047134	protein-disulfide reductase activity
0.33	GO:0005515	protein binding
0.33	GO:0016853	isomerase activity

0.39	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.48	EC:1.8.1.9	GO:0004791
0.48	KEGG:R02016	GO:0004791

tr|T1ELL0|T1ELL0_HELRO
Uncharacterized protein
Search

PDHB

0.57	Mitochondrial pyruvate dehydrogenase e1 component subunit beta

0.53	GO:0006086	acetyl-CoA biosynthetic process from pyruvate
0.48	GO:0006099	tricarboxylic acid cycle
0.45	GO:0043473	pigmentation
0.38	GO:0006006	glucose metabolic process
0.36	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate
0.35	GO:0019362	pyridine nucleotide metabolic process
0.33	GO:0006508	proteolysis

0.58	GO:0034604	pyruvate dehydrogenase (NAD+) activity
0.42	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity
0.34	GO:0008234	cysteine-type peptidase activity
0.33	GO:0005515	protein binding

0.53	GO:0045254	pyruvate dehydrogenase complex
0.48	GO:0005654	nucleoplasm
0.44	GO:0005739	mitochondrion
0.37	GO:0070062	extracellular exosome

0.58	EC:1.2.1	GO:0034604
0.58	KEGG:R00209	GO:0034604

tr|T1ELL1|T1ELL1_HELRO
Uncharacterized protein
Search

0.10	Tubulin folding cofactor C

0.84	GO:0007023	post-chaperonin tubulin folding pathway
0.45	GO:0007021	tubulin complex assembly
0.35	GO:0043547	positive regulation of GTPase activity
0.34	GO:0043461	proton-transporting ATP synthase complex assembly
0.34	GO:0000226	microtubule cytoskeleton organization
0.33	GO:0046854	phosphatidylinositol phosphorylation

0.72	GO:0015631	tubulin binding
0.59	GO:0032550	purine ribonucleoside binding
0.59	GO:0019001	guanyl nucleotide binding
0.49	GO:0032555	purine ribonucleotide binding
0.49	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0003924	GTPase activity
0.35	GO:0005096	GTPase activator activity

0.43	GO:0032391	photoreceptor connecting cilium
0.39	GO:0005829	cytosol
0.30	GO:0016020	membrane

tr|T1ELL2|T1ELL2_HELRO
Uncharacterized protein
Search

SLC30A1

0.42	Cation efflux protein/ zinc transporter

0.61	GO:0098655	cation transmembrane transport
0.48	GO:0010043	response to zinc ion
0.46	GO:0097501	stress response to metal ion
0.46	GO:0006829	zinc II ion transport
0.46	GO:0006882	cellular zinc ion homeostasis
0.41	GO:0061088	regulation of sequestering of zinc ion
0.41	GO:0098754	detoxification
0.40	GO:0098660	inorganic ion transmembrane transport
0.37	GO:0006877	cellular cobalt ion homeostasis
0.36	GO:0071276	cellular response to cadmium ion

0.61	GO:0008324	cation transmembrane transporter activity
0.41	GO:0015562	efflux transmembrane transporter activity
0.40	GO:0015318	inorganic molecular entity transmembrane transporter activity
0.34	GO:0008083	growth factor activity
0.34	GO:0070035	purine NTP-dependent helicase activity
0.33	GO:0042623	ATPase activity, coupled
0.33	GO:0008270	zinc ion binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0019855	calcium channel inhibitor activity
0.32	GO:0008144	drug binding

0.44	GO:0016323	basolateral plasma membrane
0.43	GO:0016324	apical plasma membrane
0.36	GO:0000329	fungal-type vacuole membrane
0.35	GO:0005783	endoplasmic reticulum
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0031984	organelle subcompartment
0.33	GO:0005634	nucleus
0.32	GO:0005794	Golgi apparatus
0.30	GO:0016021	integral component of membrane

0.32

GO:0032440

tr|T1ELL3|T1ELL3_HELRO
Synaptotagmin 7f
Search

SYT7

0.84	Synaptotagmin VIIa

0.75	GO:0006887	exocytosis
0.55	GO:0099643	signal release from synapse
0.55	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.53	GO:0090119	vesicle-mediated cholesterol transport
0.52	GO:0017158	regulation of calcium ion-dependent exocytosis
0.52	GO:1990926	short-term synaptic potentiation
0.52	GO:0070092	regulation of glucagon secretion
0.52	GO:0006836	neurotransmitter transport
0.51	GO:0048489	synaptic vesicle transport
0.51	GO:0099504	synaptic vesicle cycle

0.81	GO:0005544	calcium-dependent phospholipid binding
0.51	GO:0000149	SNARE binding
0.50	GO:0001786	phosphatidylserine binding
0.49	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.47	GO:0005516	calmodulin binding
0.45	GO:0030276	clathrin binding
0.42	GO:0005509	calcium ion binding

0.53	GO:0098793	presynapse
0.51	GO:0032009	early phagosome
0.50	GO:0070382	exocytic vesicle
0.49	GO:0044306	neuron projection terminus
0.48	GO:0043025	neuronal cell body
0.48	GO:0030425	dendrite
0.47	GO:0097060	synaptic membrane
0.47	GO:0005764	lysosome
0.46	GO:0005777	peroxisome
0.43	GO:0005829	cytosol

tr|T1ELL4|T1ELL4_HELRO
Uncharacterized protein
Search

0.84

Complexin

0.76	GO:0006836	neurotransmitter transport
0.38	GO:0006887	exocytosis
0.35	GO:0046929	negative regulation of neurotransmitter secretion
0.35	GO:0051124	synaptic growth at neuromuscular junction
0.35	GO:0007274	neuromuscular synaptic transmission
0.34	GO:0097480	establishment of synaptic vesicle localization
0.34	GO:0099504	synaptic vesicle cycle
0.34	GO:0099003	vesicle-mediated transport in synapse
0.34	GO:0099643	signal release from synapse
0.34	GO:0099531	presynaptic process involved in chemical synaptic transmission

0.83	GO:0019905	syntaxin binding
0.34	GO:0005326	neurotransmitter transporter activity
0.33	GO:0043022	ribosome binding
0.32	GO:0046872	metal ion binding

0.35	GO:0005829	cytosol
0.35	GO:0043195	terminal bouton
0.34	GO:0031594	neuromuscular junction
0.34	GO:0048786	presynaptic active zone
0.32	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

tr|T1ELL5|T1ELL5_HELRO
Uncharacterized protein
Search

TECR

0.78	Very-long-chain enoyl-CoA reductase

0.63	GO:0006629	lipid metabolic process
0.52	GO:0055114	oxidation-reduction process
0.44	GO:0072330	monocarboxylic acid biosynthetic process
0.36	GO:0006357	regulation of transcription by RNA polymerase II
0.35	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process
0.34	GO:1901362	organic cyclic compound biosynthetic process
0.33	GO:0016070	RNA metabolic process
0.33	GO:0006098	pentose-phosphate shunt
0.33	GO:0018130	heterocycle biosynthetic process
0.33	GO:0019438	aromatic compound biosynthetic process

0.68	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors
0.37	GO:0001104	RNA polymerase II transcription cofactor activity
0.34	GO:0004345	glucose-6-phosphate dehydrogenase activity
0.34	GO:0016779	nucleotidyltransferase activity
0.33	GO:0050661	NADP binding
0.33	GO:0005515	protein binding
0.32	GO:0003677	DNA binding

0.49	GO:0005737	cytoplasm
0.42	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.41	GO:0031984	organelle subcompartment
0.39	GO:0043231	intracellular membrane-bounded organelle
0.36	GO:0031461	cullin-RING ubiquitin ligase complex
0.36	GO:0031974	membrane-enclosed lumen
0.35	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.68

EC:1.3

GO:0016627

tr|T1ELL6|T1ELL6_HELRO
Uncharacterized protein
Search

0.77	39S ribosomal protein L40, mitochondrial (inferred by orthology to a human protein)

0.42	GO:0032543	mitochondrial translation
0.36	GO:0006231	dTMP biosynthetic process
0.34	GO:0032259	methylation

0.38	GO:0003735	structural constituent of ribosome
0.36	GO:0004799	thymidylate synthase activity

0.61	GO:0005840	ribosome
0.51	GO:0005759	mitochondrial matrix

0.36	EC:2.1.1.45	GO:0004799
0.36	KEGG:R02101	GO:0004799

tr|T1ELL7|T1ELL7_HELRO
Uncharacterized protein
Search

tr|T1ELL8|T1ELL8_HELRO
Uncharacterized protein
Search

0.81	Tubulin polyglutamylase TTLL4

0.85	GO:0018095	protein polyglutamylation
0.40	GO:0042060	wound healing
0.33	GO:0031047	gene silencing by RNA
0.32	GO:0055114	oxidation-reduction process

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0070739	protein-glutamic acid ligase activity
0.37	GO:0015631	tubulin binding
0.33	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.33	GO:0020037	heme binding
0.33	GO:0005506	iron ion binding
0.32	GO:0003676	nucleic acid binding

0.30

GO:0031224

intrinsic component of membrane

0.40

EC:6.3.2

GO:0070739

tr|T1ELL9|T1ELL9_HELRO
Transcription elongation factor SPT4
Search

SUPT4H1

0.68	Transcription elongation factor SPT4-A

0.80	GO:0032786	positive regulation of DNA-templated transcription, elongation
0.56	GO:0006351	transcription, DNA-templated
0.55	GO:0032785	negative regulation of DNA-templated transcription, elongation
0.54	GO:0006414	translational elongation
0.54	GO:0034243	regulation of transcription elongation from RNA polymerase II promoter
0.50	GO:0000122	negative regulation of transcription by RNA polymerase II
0.47	GO:0045944	positive regulation of transcription by RNA polymerase II
0.46	GO:0006325	chromatin organization
0.45	GO:0006397	mRNA processing
0.39	GO:0090262	regulation of transcription-coupled nucleotide-excision repair

0.62	GO:0008270	zinc ion binding
0.54	GO:0003746	translation elongation factor activity
0.53	GO:0000993	RNA polymerase II core binding
0.49	GO:0003727	single-stranded RNA binding
0.46	GO:0046982	protein heterodimerization activity
0.41	GO:0003700	DNA binding transcription factor activity
0.39	GO:0000182	rDNA binding

0.61	GO:0005634	nucleus
0.49	GO:0043233	organelle lumen
0.45	GO:0043234	protein complex
0.44	GO:0044446	intracellular organelle part
0.40	GO:0005700	polytene chromosome

tr|T1ELM0|T1ELM0_HELRO
Uncharacterized protein
Search

0.77	GO:0070588	calcium ion transmembrane transport
0.70	GO:0034765	regulation of ion transmembrane transport
0.43	GO:0035545	determination of left/right asymmetry in nervous system
0.41	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.41	GO:0007626	locomotory behavior
0.40	GO:0042594	response to starvation
0.39	GO:0009408	response to heat
0.39	GO:0001505	regulation of neurotransmitter levels
0.38	GO:0086010	membrane depolarization during action potential

0.82	GO:0005245	voltage-gated calcium channel activity
0.65	GO:0005509	calcium ion binding

0.81	GO:0005891	voltage-gated calcium channel complex
0.43	GO:0048787	presynaptic active zone membrane

tr|T1ELM1|T1ELM1_HELRO
Uncharacterized protein
Search

CHMP4B

0.87	Charged multivesicular body protein 4Ba

0.79	GO:0007034	vacuolar transport
0.52	GO:0036438	maintenance of lens transparency
0.52	GO:0090611	ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway
0.52	GO:0090148	membrane fission
0.51	GO:0010458	exit from mitosis
0.51	GO:1902902	negative regulation of autophagosome assembly
0.51	GO:1902188	positive regulation of viral release from host cell
0.51	GO:0031468	nuclear envelope reassembly
0.50	GO:1901673	regulation of mitotic spindle assembly
0.50	GO:0000920	cell separation after cytokinesis

0.48	GO:0045296	cadherin binding
0.46	GO:0042803	protein homodimerization activity
0.33	GO:0005215	transporter activity
0.33	GO:0003700	DNA binding transcription factor activity

0.51	GO:0000815	ESCRT III complex
0.49	GO:0030496	midbody
0.47	GO:0005635	nuclear envelope
0.46	GO:0009898	cytoplasmic side of plasma membrane
0.46	GO:0048475	coated membrane
0.44	GO:0005829	cytosol
0.39	GO:0031902	late endosome membrane
0.34	GO:0070062	extracellular exosome
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0031224	intrinsic component of membrane

tr|T1ELM2|T1ELM2_HELRO
Uncharacterized protein
Search

0.42	Putative serine/threonine protein phosphatase

0.72	GO:0006470	protein dephosphorylation
0.37	GO:0030517	negative regulation of axon extension
0.37	GO:0051965	positive regulation of synapse assembly

0.77	GO:0004722	protein serine/threonine phosphatase activity
0.52	GO:0046872	metal ion binding
0.36	GO:0031625	ubiquitin protein ligase binding

0.37	GO:0048786	presynaptic active zone
0.33	GO:0005829	cytosol
0.32	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

tr|T1ELM3|T1ELM3_HELRO
Uncharacterized protein
Search

0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.64	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.45	GO:0006182	cGMP biosynthetic process
0.44	GO:0071469	cellular response to alkaline pH
0.43	GO:0045464	R8 cell fate specification
0.43	GO:0045678	positive regulation of R7 cell differentiation
0.43	GO:0007465	R7 cell fate commitment
0.42	GO:0042067	establishment of ommatidial planar polarity
0.39	GO:0046777	protein autophosphorylation
0.37	GO:0048680	positive regulation of axon regeneration

0.77	GO:0004713	protein tyrosine kinase activity
0.65	GO:0019199	transmembrane receptor protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.45	GO:0004383	guanylate cyclase activity
0.38	GO:0043560	insulin receptor substrate binding
0.37	GO:0043548	phosphatidylinositol 3-kinase binding
0.37	GO:0031435	mitogen-activated protein kinase kinase kinase binding

0.41	GO:0005887	integral component of plasma membrane
0.35	GO:0098533	ATPase dependent transmembrane transport complex
0.35	GO:0098797	plasma membrane protein complex
0.33	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane

0.77

EC:2.7.10

GO:0004713

tr|T1ELM4|T1ELM4_HELRO
Uncharacterized protein
Search

ACTL6B

0.58	BRG1/brm-associated factor 53A

0.75	GO:0006338	chromatin remodeling
0.56	GO:0007399	nervous system development
0.55	GO:1903146	regulation of autophagy of mitochondrion
0.55	GO:0043968	histone H2A acetylation
0.54	GO:0003407	neural retina development
0.54	GO:1903955	positive regulation of protein targeting to mitochondrion
0.54	GO:0043967	histone H4 acetylation
0.37	GO:0040008	regulation of growth
0.36	GO:0006351	transcription, DNA-templated
0.36	GO:1903506	regulation of nucleic acid-templated transcription

0.50	GO:0003682	chromatin binding
0.37	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.36	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.36	GO:0003713	transcription coactivator activity
0.35	GO:0033570	transferrin transmembrane transporter activity
0.35	GO:0044877	macromolecular complex binding
0.35	GO:0005515	protein binding
0.34	GO:0005200	structural constituent of cytoskeleton

0.76	GO:0071564	npBAF complex
0.61	GO:0016514	SWI/SNF complex
0.52	GO:0071565	nBAF complex
0.52	GO:0035267	NuA4 histone acetyltransferase complex
0.51	GO:0031011	Ino80 complex
0.48	GO:0005730	nucleolus
0.41	GO:0005886	plasma membrane

tr|T1ELM5|T1ELM5_HELRO
tRNA(His) guanylyltransferase
Search

THG1L

0.82	tRNA(His) guanylyltransferase

0.63	GO:0006400	tRNA modification
0.47	GO:0051289	protein homotetramerization
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0009059	macromolecule biosynthetic process

0.79	GO:0008193	tRNA guanylyltransferase activity
0.61	GO:0032550	purine ribonucleoside binding
0.61	GO:0019001	guanyl nucleotide binding
0.60	GO:0000287	magnesium ion binding
0.51	GO:0032555	purine ribonucleotide binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0042802	identical protein binding
0.38	GO:0030554	adenyl nucleotide binding
0.38	GO:0008144	drug binding
0.33	GO:0000049	tRNA binding

0.40	GO:0005739	mitochondrion
0.33	GO:0005829	cytosol
0.33	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.79

EC:2.7.7

GO:0008193

tr|T1ELM6|T1ELM6_HELRO
Uncharacterized protein
Search

MED22

0.90	Mediator of RNA polymerase II transcription subunit 22

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.39	GO:0007406	negative regulation of neuroblast proliferation
0.38	GO:0007283	spermatogenesis
0.36	GO:0006351	transcription, DNA-templated
0.34	GO:0000278	mitotic cell cycle
0.33	GO:0005975	carbohydrate metabolic process
0.32	GO:0036211	protein modification process
0.32	GO:0044267	cellular protein metabolic process

0.79	GO:0001104	RNA polymerase II transcription cofactor activity
0.36	GO:0016787	hydrolase activity
0.34	GO:0005515	protein binding
0.33	GO:0016758	transferase activity, transferring hexosyl groups

0.77	GO:0016592	mediator complex
0.37	GO:0005730	nucleolus
0.37	GO:0000785	chromatin
0.33	GO:0019013	viral nucleocapsid
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.36

GO:0016787

tr|T1ELM7|T1ELM7_HELRO
Uncharacterized protein
Search

MTFP1

0.63	Mitochondrial fission process protein 1 (inferred by orthology to a human protein)

0.69	GO:0000266	mitochondrial fission
0.44	GO:0014850	response to muscle activity
0.42	GO:0006915	apoptotic process
0.36	GO:0007006	mitochondrial membrane organization
0.34	GO:0006508	proteolysis
0.33	GO:0055085	transmembrane transport

0.35	GO:0008235	metalloexopeptidase activity
0.35	GO:0030145	manganese ion binding
0.35	GO:0004177	aminopeptidase activity

0.52	GO:0005739	mitochondrion
0.51	GO:0019866	organelle inner membrane
0.30	GO:0044425	membrane part

0.35

EC:3.4.11

GO:0004177

tr|T1ELM8|T1ELM8_HELRO
Uncharacterized protein
Search

FHL2

0.88	Four and a half LIM domains protein 5

0.62	GO:0055014	atrial cardiac muscle cell development
0.60	GO:0055015	ventricular cardiac muscle cell development
0.60	GO:0060347	heart trabecula formation
0.58	GO:0001649	osteoblast differentiation
0.54	GO:0043066	negative regulation of apoptotic process
0.54	GO:0000122	negative regulation of transcription by RNA polymerase II
0.52	GO:0009725	response to hormone
0.36	GO:0030522	intracellular receptor signaling pathway
0.36	GO:0019216	regulation of lipid metabolic process
0.36	GO:0006351	transcription, DNA-templated

0.54	GO:0046872	metal ion binding
0.52	GO:0042802	identical protein binding
0.51	GO:0008134	transcription factor binding
0.36	GO:0051427	hormone receptor binding
0.36	GO:0003713	transcription coactivator activity

0.46	GO:0005634	nucleus
0.43	GO:0031430	M band
0.42	GO:0030018	Z disc
0.38	GO:0005925	focal adhesion
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part

tr|T1ELM9|T1ELM9_HELRO
Uncharacterized protein
Search

GNAO1

0.75	Guanine nucleotide binding protein alpha O

0.81	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.49	GO:0007212	dopamine receptor signaling pathway
0.45	GO:0008016	regulation of heart contraction
0.45	GO:0007626	locomotory behavior
0.41	GO:1903554	G-protein coupled receptor signaling pathway involved in defense response to Gram-negative bacterium
0.39	GO:0071321	cellular response to cGMP
0.39	GO:0040024	dauer larval development
0.39	GO:0001306	age-dependent response to oxidative stress
0.39	GO:0050913	sensory perception of bitter taste
0.38	GO:0008340	determination of adult lifespan

0.81	GO:0031683	G-protein beta/gamma-subunit complex binding
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.64	GO:0004871	signal transducer activity
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0031821	G-protein coupled serotonin receptor binding
0.46	GO:0031852	mu-type opioid receptor binding
0.46	GO:0051430	corticotropin-releasing hormone receptor 1 binding

0.47	GO:0044297	cell body
0.46	GO:0036477	somatodendritic compartment
0.46	GO:0043005	neuron projection
0.45	GO:0043209	myelin sheath
0.45	GO:1905360	GTPase complex
0.45	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.43	GO:0120038	plasma membrane bounded cell projection part
0.41	GO:0098797	plasma membrane protein complex
0.39	GO:0097730	non-motile cilium
0.34	GO:0005615	extracellular space

tr|T1ELN0|T1ELN0_HELRO
Uncharacterized protein
Search

0.85	ADP-ribosylation factorB-A

0.42	GO:0032418	lysosome localization
0.41	GO:0007059	chromosome segregation
0.36	GO:0051301	cell division
0.36	GO:0007049	cell cycle
0.34	GO:1903963	arachidonate transport
0.34	GO:0032309	icosanoid secretion
0.33	GO:0016042	lipid catabolic process
0.33	GO:0006644	phospholipid metabolic process

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0043014	alpha-tubulin binding
0.42	GO:0048487	beta-tubulin binding
0.34	GO:0004623	phospholipase A2 activity
0.33	GO:0005509	calcium ion binding

0.45	GO:0005622	intracellular
0.44	GO:0030496	midbody
0.41	GO:0098805	whole membrane
0.41	GO:0098588	bounding membrane of organelle
0.38	GO:0043228	non-membrane-bounded organelle
0.37	GO:0031982	vesicle
0.36	GO:0012505	endomembrane system
0.34	GO:0005576	extracellular region

0.34

EC:3.1.1.4

GO:0004623

tr|T1ELN1|T1ELN1_HELRO
Uncharacterized protein
Search

HEATR5B

0.73	HEAT repeat-containing protein 5B

0.53

GO:0006751

glutathione catabolic process

0.54	GO:0003839	gamma-glutamylcyclotransferase activity
0.48	GO:0005515	protein binding

0.66	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.54

EC:2.3.2.4

GO:0003839

tr|T1ELN2|T1ELN2_HELRO
Uncharacterized protein
Search

NAA30

0.73	N-alpha-acetyltransferase 30, NatC catalytic subunit

0.52

GO:0017196

N-terminal peptidyl-methionine acetylation

0.68	GO:0008080	N-acetyltransferase activity
0.33	GO:0005515	protein binding

0.54	GO:0031417	NatC complex
0.50	GO:0005844	polysome
0.44	GO:0005829	cytosol
0.42	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0008080

tr|T1ELN3|T1ELN3_HELRO
Uncharacterized protein
Search

BCDIN3D

0.97	pre-miRNA 5'-monophosphate methyltransferase

0.63	GO:0032259	methylation
0.58	GO:2000632	negative regulation of pre-miRNA processing
0.56	GO:0010586	miRNA metabolic process
0.45	GO:0009451	RNA modification
0.38	GO:0044260	cellular macromolecule metabolic process

0.63	GO:0008168	methyltransferase activity
0.44	GO:0140098	catalytic activity, acting on RNA
0.34	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.46	GO:0005829	cytosol
0.43	GO:0005634	nucleus

0.63

GO:0008168

tr|T1ELN4|T1ELN4_HELRO
Uncharacterized protein
Search

0.82	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process
0.81	GO:0048015	phosphatidylinositol-mediated signaling
0.75	GO:0046854	phosphatidylinositol phosphorylation
0.48	GO:0044029	hypomethylation of CpG island
0.48	GO:0030168	platelet activation
0.48	GO:2000653	regulation of genetic imprinting
0.47	GO:2000811	negative regulation of anoikis
0.47	GO:2000270	negative regulation of fibroblast apoptotic process
0.47	GO:0002250	adaptive immune response
0.47	GO:0048638	regulation of developmental growth

0.84	GO:0016303	1-phosphatidylinositol-3-kinase activity
0.50	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.50	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity
0.47	GO:0043560	insulin receptor substrate binding
0.45	GO:0030295	protein kinase activator activity
0.36	GO:1902379	chemoattractant activity involved in axon guidance
0.34	GO:0004672	protein kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding

0.54	GO:0005943	phosphatidylinositol 3-kinase complex, class IA
0.45	GO:0005622	intracellular
0.45	GO:0030027	lamellipodium
0.38	GO:0005886	plasma membrane
0.35	GO:0090723	growth cone part
0.30	GO:0016021	integral component of membrane

0.84	EC:2.7.1.137	GO:0016303
0.84	KEGG:R03362	GO:0016303

tr|T1ELN5|T1ELN5_HELRO
Uncharacterized protein
Search

AMDHD1

0.48	Imidazolonepropionase

0.78	GO:0043606	formamide metabolic process
0.78	GO:0006548	histidine catabolic process
0.74	GO:0006536	glutamate metabolic process
0.40	GO:0015942	formate metabolic process
0.37	GO:0000387	spliceosomal snRNP assembly

0.75	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
0.35	GO:0046872	metal ion binding

0.49	GO:0005737	cytoplasm
0.36	GO:0005681	spliceosomal complex

0.75

EC:3.5.2

GO:0016812

tr|T1ELN6|T1ELN6_HELRO
Uncharacterized protein
Search

COPG2

0.69	Coatomer subunit gamma

0.69	GO:0006886	intracellular protein transport
0.68	GO:0016192	vesicle-mediated transport
0.35	GO:0035158	regulation of tube diameter, open tracheal system
0.35	GO:0007436	larval salivary gland morphogenesis
0.35	GO:0035147	branch fusion, open tracheal system
0.35	GO:0035149	lumen formation, open tracheal system
0.35	GO:0008362	chitin-based embryonic cuticle biosynthetic process
0.34	GO:0007112	male meiosis cytokinesis
0.34	GO:0010883	regulation of lipid storage
0.34	GO:0000281	mitotic cytokinesis

0.61	GO:0005198	structural molecule activity
0.33	GO:0005515	protein binding

0.80	GO:0030126	COPI vesicle coat
0.69	GO:0000139	Golgi membrane
0.36	GO:0005829	cytosol
0.35	GO:0030133	transport vesicle
0.35	GO:0005783	endoplasmic reticulum
0.35	GO:0036063	acroblast
0.34	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.34	GO:0099503	secretory vesicle
0.34	GO:0005801	cis-Golgi network
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network

tr|T1ELN7|T1ELN7_HELRO
Ubiquitinyl hydrolase 1
Search

0.38	Ubiquitin carboxyl-terminal hydrolase

0.76	GO:0016579	protein deubiquitination
0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.37	GO:0007399	nervous system development

0.78	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.58	GO:0008270	zinc ion binding

0.30

GO:0031224

intrinsic component of membrane

tr|T1ELN8|T1ELN8_HELRO
Uncharacterized protein
Search

RPS9

0.69	Ribosomal protein S9

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.46	GO:0045903	positive regulation of translational fidelity
0.46	GO:0008284	positive regulation of cell proliferation
0.34	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.34	GO:0034660	ncRNA metabolic process
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane

0.66	GO:0019843	rRNA binding
0.64	GO:0003735	structural constituent of ribosome
0.47	GO:0045182	translation regulator activity
0.36	GO:0000213	tRNA-intron endonuclease activity
0.33	GO:0005515	protein binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.70	GO:0015935	small ribosomal subunit
0.48	GO:0022626	cytosolic ribosome
0.47	GO:0005730	nucleolus
0.40	GO:0000228	nuclear chromosome
0.36	GO:0005925	focal adhesion
0.35	GO:0070062	extracellular exosome
0.33	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.36

EC:3.1.27.9

GO:0000213

tr|T1ELN9|T1ELN9_HELRO
Uncharacterized protein
Search

0.62	Regulator of G-protein signaling

0.82	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.69	GO:0007186	G-protein coupled receptor signaling pathway
0.62	GO:0035556	intracellular signal transduction
0.39	GO:0043547	positive regulation of GTPase activity
0.38	GO:0042407	cristae formation
0.34	GO:0046662	regulation of oviposition
0.34	GO:0007622	rhythmic behavior
0.34	GO:0007631	feeding behavior
0.33	GO:0040017	positive regulation of locomotion
0.33	GO:0046854	phosphatidylinositol phosphorylation

0.63	GO:0004871	signal transducer activity
0.39	GO:0005096	GTPase activator activity
0.32	GO:0003735	structural constituent of ribosome

0.79	GO:1905360	GTPase complex
0.78	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.64	GO:0098797	plasma membrane protein complex
0.38	GO:0061617	MICOS complex
0.33	GO:0043005	neuron projection
0.32	GO:0005840	ribosome

tr|T1ELP0|T1ELP0_HELRO
Uncharacterized protein
Search

0.50	coiled-coil domain-containing protein 130

0.72	GO:0009615	response to virus
0.38	GO:0043413	macromolecule glycosylation
0.38	GO:0009101	glycoprotein biosynthetic process
0.37	GO:0032259	methylation
0.35	GO:0006464	cellular protein modification process

0.40	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity
0.37	GO:0008168	methyltransferase activity
0.37	GO:0005515	protein binding
0.35	GO:0003676	nucleic acid binding
0.34	GO:0046872	metal ion binding

0.38	GO:0000139	Golgi membrane
0.30	GO:0044425	membrane part

0.40

EC:2.4.1.135

GO:0015018

tr|T1ELP1|T1ELP1_HELRO
Uncharacterized protein
Search

DYNLT1

0.90	Dynein molecular motor protein light chain

0.86	GO:0019060	intracellular transport of viral protein in host cell
0.51	GO:0000132	establishment of mitotic spindle orientation
0.50	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.50	GO:0050768	negative regulation of neurogenesis
0.47	GO:0010976	positive regulation of neuron projection development
0.47	GO:1905709	negative regulation of membrane permeability
0.47	GO:0035022	positive regulation of Rac protein signal transduction
0.45	GO:0046902	regulation of mitochondrial membrane permeability
0.44	GO:0016358	dendrite development
0.44	GO:0051301	cell division

0.73	GO:0042802	identical protein binding
0.46	GO:0003774	motor activity
0.44	GO:0008022	protein C-terminus binding
0.42	GO:0031681	G-protein beta-subunit binding
0.41	GO:0030742	GTP-dependent protein binding

0.83	GO:0005868	cytoplasmic dynein complex
0.83	GO:0005881	cytoplasmic microtubule
0.78	GO:0099503	secretory vesicle
0.62	GO:0044216	other organism cell
0.62	GO:0018995	host
0.48	GO:0030426	growth cone
0.48	GO:0005819	spindle
0.46	GO:0044297	cell body
0.46	GO:0005794	Golgi apparatus
0.44	GO:0030027	lamellipodium

tr|T1ELP2|T1ELP2_HELRO
Uncharacterized protein
Search

TRAPPC6B

0.90	Trafficking protein particle complex subunit 6B

0.76	GO:0048193	Golgi vesicle transport
0.75	GO:0043087	regulation of GTPase activity
0.44	GO:0046907	intracellular transport
0.39	GO:0048868	pollen tube development
0.38	GO:0009737	response to abscisic acid
0.35	GO:0006900	vesicle budding from membrane
0.34	GO:0006903	vesicle targeting
0.33	GO:0006461	protein complex assembly
0.33	GO:0034613	cellular protein localization
0.33	GO:0015031	protein transport

0.34

GO:0017112

Rab guanyl-nucleotide exchange factor activity

0.48	GO:0005801	cis-Golgi network
0.48	GO:0030008	TRAPP complex
0.47	GO:0005802	trans-Golgi network
0.36	GO:0005783	endoplasmic reticulum
0.35	GO:0000139	Golgi membrane
0.34	GO:0030127	COPII vesicle coat
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|T1ELP3|T1ELP3_HELRO
Uncharacterized protein
Search

DNAJB5

0.81	DnaJ like protein subfamily B member 4

0.69	GO:0006457	protein folding
0.49	GO:0006986	response to unfolded protein
0.47	GO:0000122	negative regulation of transcription by RNA polymerase II
0.41	GO:0032781	positive regulation of ATPase activity

0.71	GO:0051082	unfolded protein binding
0.49	GO:0051087	chaperone binding
0.41	GO:0001671	ATPase activator activity
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0032561	guanyl ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.46	GO:0005829	cytosol
0.43	GO:0005634	nucleus
0.38	GO:0031974	membrane-enclosed lumen
0.36	GO:0044446	intracellular organelle part
0.36	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1ELP4|T1ELP4_HELRO
Uncharacterized protein
Search

0.40	Glutaminase kidney isoform, mitochondrial

0.71	GO:0006541	glutamine metabolic process
0.34	GO:0006537	glutamate biosynthetic process
0.34	GO:0009065	glutamine family amino acid catabolic process
0.32	GO:0055114	oxidation-reduction process

0.79	GO:0004359	glutaminase activity
0.32	GO:0003676	nucleic acid binding

0.37	GO:0005739	mitochondrion
0.33	GO:0070013	intracellular organelle lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.79

EC:3.5.1.2

GO:0004359

tr|T1ELP5|T1ELP5_HELRO
Nicotinate-nucleotide pyrophosphorylase [carboxylating]
Search

QPRT

0.63	Nicotinate-nucleotide pyrophosphorylase [carboxylating]

0.72	GO:0009435	NAD biosynthetic process
0.44	GO:0034213	quinolinate catabolic process
0.36	GO:0006568	tryptophan metabolic process

0.76	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity
0.33	GO:0016874	ligase activity

0.34

GO:0005737

cytoplasm

0.76	EC:2.4.2.19	GO:0004514
0.76	KEGG:R03348	GO:0004514

tr|T1ELP6|T1ELP6_HELRO
Uncharacterized protein
Search

SLC25A35

0.81	Mitochondrial fatty acid anion carrier protein/uncoupling protein

0.46	GO:0006839	mitochondrial transport
0.38	GO:0055085	transmembrane transport
0.35	GO:0090226	regulation of microtubule nucleation by Ran protein signal transduction
0.35	GO:0098905	regulation of bundle of His cell action potential
0.35	GO:1900825	regulation of membrane depolarization during cardiac muscle cell action potential
0.35	GO:0098909	regulation of cardiac muscle cell action potential involved in regulation of contraction
0.35	GO:2000010	positive regulation of protein localization to cell surface
0.35	GO:0032527	protein exit from endoplasmic reticulum
0.35	GO:2000649	regulation of sodium ion transmembrane transporter activity
0.35	GO:1903078	positive regulation of protein localization to plasma membrane

0.39	GO:0022857	transmembrane transporter activity
0.35	GO:0005087	Ran guanyl-nucleotide exchange factor activity
0.35	GO:0017080	sodium channel regulator activity
0.34	GO:0044325	ion channel binding
0.33	GO:0019894	kinesin binding
0.33	GO:0008565	protein transporter activity

0.44	GO:0005739	mitochondrion
0.41	GO:0019866	organelle inner membrane
0.35	GO:0014704	intercalated disc
0.34	GO:0005901	caveola
0.34	GO:0005791	rough endoplasmic reticulum
0.33	GO:0005654	nucleoplasm
0.33	GO:0005829	cytosol
0.33	GO:0010008	endosome membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1ELP7|T1ELP7_HELRO
Uncharacterized protein
Search

0.45	Cell division cycle 5 like

0.55	GO:0072422	signal transduction involved in DNA damage checkpoint
0.55	GO:0051301	cell division
0.50	GO:0006366	transcription by RNA polymerase II
0.50	GO:0000398	mRNA splicing, via spliceosome
0.50	GO:0045944	positive regulation of transcription by RNA polymerase II
0.43	GO:0030154	cell differentiation
0.38	GO:1904567	response to wortmannin
0.37	GO:1990646	cellular response to prolactin
0.37	GO:0071352	cellular response to interleukin-2
0.37	GO:1990090	cellular response to nerve growth factor stimulus

0.58	GO:0071987	WD40-repeat domain binding
0.55	GO:0003677	DNA binding
0.53	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.52	GO:0001067	regulatory region nucleic acid binding
0.48	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting
0.37	GO:0043522	leucine zipper domain binding
0.37	GO:0001222	transcription corepressor binding
0.36	GO:0008157	protein phosphatase 1 binding
0.35	GO:0019901	protein kinase binding
0.35	GO:0003723	RNA binding

0.55	GO:0005662	DNA replication factor A complex
0.55	GO:0071007	U2-type catalytic step 2 spliceosome
0.54	GO:0000974	Prp19 complex
0.52	GO:0016607	nuclear speck
0.39	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.34

EC:1.11.1.15

GO:0051920

tr|T1ELP8|T1ELP8_HELRO
Uncharacterized protein
Search

KLHL3

0.78	Kelch like family member 3

0.79	GO:0072156	distal tubule morphogenesis
0.78	GO:0070294	renal sodium ion absorption
0.74	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.73	GO:0070936	protein K48-linked ubiquitination
0.62	GO:0050801	ion homeostasis

0.59	GO:0004842	ubiquitin-protein transferase activity
0.51	GO:0003779	actin binding
0.40	GO:0003723	RNA binding

0.78	GO:0031463	Cul3-RING ubiquitin ligase complex
0.59	GO:0005829	cytosol
0.49	GO:0005856	cytoskeleton
0.30	GO:0016020	membrane

0.59

KEGG:R03876

GO:0004842

tr|T1ELP9|T1ELP9_HELRO
Uncharacterized protein
Search

MRPL28

0.96	39S ribosomal protein L28, mitochondrial (inferred by orthology to a human protein)

0.44	GO:0006421	asparaginyl-tRNA aminoacylation
0.36	GO:0006487	protein N-linked glycosylation
0.35	GO:0070126	mitochondrial translational termination
0.35	GO:0070125	mitochondrial translational elongation
0.33	GO:0016567	protein ubiquitination

0.64	GO:0003735	structural constituent of ribosome
0.44	GO:0004816	asparagine-tRNA ligase activity
0.37	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0003676	nucleic acid binding
0.33	GO:0005515	protein binding

0.53	GO:0005840	ribosome
0.50	GO:0005759	mitochondrial matrix
0.45	GO:0005829	cytosol
0.37	GO:0008250	oligosaccharyltransferase complex
0.34	GO:0031966	mitochondrial membrane
0.34	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

0.44	EC:6.1.1.22	GO:0004816
0.44	KEGG:R03648	GO:0004816

tr|T1ELQ0|T1ELQ0_HELRO
Uncharacterized protein
Search

0.73	Glutathione S-transferase C-terminal domain containing

0.47	GO:0016740	transferase activity
0.34	GO:0005515	protein binding

0.48	GO:0005654	nucleoplasm
0.40	GO:0005737	cytoplasm
0.37	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.47

GO:0016740

tr|T1ELQ1|T1ELQ1_HELRO
Tubulin beta chain
Search

0.49	Tubulin beta chain

0.72	GO:0007017	microtubule-based process
0.71	GO:0007010	cytoskeleton organization
0.37	GO:0070925	organelle assembly
0.36	GO:0022402	cell cycle process

0.77	GO:0005200	structural constituent of cytoskeleton
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032553	ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.73	GO:0005874	microtubule
0.46	GO:0005737	cytoplasm

tr|T1ELQ2|T1ELQ2_HELRO
Uncharacterized protein
Search

ADAP1

0.85	Arf-GAP with dual PH domain-containing protein 1

0.76	GO:0043547	positive regulation of GTPase activity
0.38	GO:0007507	heart development
0.35	GO:0007368	determination of left/right symmetry
0.35	GO:0048562	embryonic organ morphogenesis
0.35	GO:0060562	epithelial tube morphogenesis
0.33	GO:0007186	G-protein coupled receptor signaling pathway
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.83	GO:1902936	phosphatidylinositol bisphosphate binding
0.76	GO:0005096	GTPase activator activity
0.50	GO:0046872	metal ion binding
0.38	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding
0.37	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.33	GO:0003924	GTPase activity
0.33	GO:0004930	G-protein coupled receptor activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.33	GO:0043565	sequence-specific DNA binding

0.39	GO:0005829	cytosol
0.37	GO:0005634	nucleus
0.37	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1ELQ3|T1ELQ3_HELRO
Uncharacterized protein
Search

0.10	Sodium leak channel, non-selective

0.61	GO:0098655	cation transmembrane transport
0.48	GO:0086010	membrane depolarization during action potential
0.46	GO:0006816	calcium ion transport
0.40	GO:0034765	regulation of ion transmembrane transport
0.39	GO:0060075	regulation of resting membrane potential
0.37	GO:0098660	inorganic ion transmembrane transport
0.36	GO:0071804	cellular potassium ion transport
0.36	GO:0006814	sodium ion transport

0.74	GO:0005261	cation channel activity
0.39	GO:0022832	voltage-gated channel activity
0.39	GO:0022839	ion gated channel activity
0.39	GO:0008381	mechanosensitive ion channel activity
0.38	GO:0022842	narrow pore channel activity
0.38	GO:0046873	metal ion transmembrane transporter activity
0.37	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0015077	monovalent inorganic cation transmembrane transporter activity
0.35	GO:0008144	drug binding

0.39	GO:0005886	plasma membrane
0.38	GO:0034704	calcium channel complex
0.34	GO:0005634	nucleus

tr|T1ELQ4|T1ELQ4_HELRO
Proteasome subunit beta type
Search

0.52	Proteasome subunit beta type

0.72	GO:0051603	proteolysis involved in cellular protein catabolic process
0.62	GO:0043632	modification-dependent macromolecule catabolic process
0.48	GO:0002376	immune system process
0.47	GO:2000116	regulation of cysteine-type endopeptidase activity
0.35	GO:1901423	response to benzene
0.34	GO:0071257	cellular response to electrical stimulus
0.34	GO:0014889	muscle atrophy
0.34	GO:0043279	response to alkaloid
0.34	GO:0071347	cellular response to interleukin-1
0.34	GO:0098586	cellular response to virus

0.77	GO:0070003	threonine-type peptidase activity
0.65	GO:0004175	endopeptidase activity
0.34	GO:0045296	cadherin binding
0.34	GO:0070628	proteasome binding

0.76	GO:0005839	proteasome core complex
0.56	GO:0005634	nucleus
0.45	GO:0005737	cytoplasm
0.36	GO:1990111	spermatoproteasome complex
0.34	GO:0070062	extracellular exosome
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

tr|T1ELQ5|T1ELQ5_HELRO
Non-specific serine/threonine protein kinase
Search

0.57	Non-specific serine/threonine protein kinase

0.63	GO:0006468	protein phosphorylation
0.42	GO:0032007	negative regulation of TOR signaling
0.41	GO:0042149	cellular response to glucose starvation
0.41	GO:0018209	peptidyl-serine modification
0.40	GO:0016570	histone modification
0.37	GO:0043066	negative regulation of apoptotic process
0.37	GO:0016241	regulation of macroautophagy
0.37	GO:0042752	regulation of circadian rhythm
0.37	GO:0042593	glucose homeostasis
0.37	GO:0007165	signal transduction

0.70	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0035173	histone kinase activity
0.38	GO:0060089	molecular transducer activity
0.36	GO:0003682	chromatin binding
0.36	GO:0004712	protein serine/threonine/tyrosine kinase activity
0.35	GO:0050405	[acetyl-CoA carboxylase] kinase activity

0.41	GO:0031588	nucleotide-activated protein kinase complex
0.37	GO:0005634	nucleus
0.36	GO:0005794	Golgi apparatus
0.34	GO:0098588	bounding membrane of organelle
0.34	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

0.70

GO:0004674

tr|T1ELQ6|T1ELQ6_HELRO
Uncharacterized protein
Search

0.24	Alpha-galactosidase A

0.60	GO:0005975	carbohydrate metabolic process
0.43	GO:0016139	glycoside catabolic process
0.42	GO:0046477	glycosylceramide catabolic process
0.35	GO:0051001	negative regulation of nitric-oxide synthase activity
0.35	GO:0045019	negative regulation of nitric oxide biosynthetic process
0.35	GO:0043312	neutrophil degranulation
0.33	GO:0009057	macromolecule catabolic process

0.66	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.38	GO:0042803	protein homodimerization activity
0.38	GO:0005102	receptor binding
0.37	GO:0016936	galactoside binding
0.35	GO:0030248	cellulose binding
0.33	GO:0016875	ligase activity, forming carbon-oxygen bonds
0.33	GO:0140101	catalytic activity, acting on a tRNA

0.40	GO:0005764	lysosome
0.40	GO:0005576	extracellular region
0.38	GO:0005794	Golgi apparatus
0.35	GO:0034774	secretory granule lumen
0.35	GO:0005775	vacuolar lumen
0.32	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.66

EC:3.2.1

GO:0004553

tr|T1ELQ7|T1ELQ7_HELRO
Uncharacterized protein
Search

RSPH9

0.94	Radial spoke head protein 9

0.84	GO:0035082	axoneme assembly
0.84	GO:0003341	cilium movement
0.68	GO:0060285	cilium-dependent cell motility
0.67	GO:0044458	motile cilium assembly

0.37

GO:0005515

protein binding

0.43	GO:0005929	cilium
0.41	GO:0005856	cytoskeleton
0.40	GO:0032838	plasma membrane bounded cell projection cytoplasm
0.36	GO:0044446	intracellular organelle part

tr|T1ELQ8|T1ELQ8_HELRO
Uncharacterized protein
Search

DNAI2

0.66	Dynein axonemal intermediate chain 2

0.83	GO:0036158	outer dynein arm assembly
0.78	GO:0003341	cilium movement
0.75	GO:0007368	determination of left/right symmetry
0.38	GO:0007186	G-protein coupled receptor signaling pathway
0.34	GO:1902476	chloride transmembrane transport

0.72	GO:0045504	dynein heavy chain binding
0.71	GO:0003777	microtubule motor activity
0.70	GO:0045503	dynein light chain binding
0.54	GO:0042623	ATPase activity, coupled
0.39	GO:0008017	microtubule binding
0.38	GO:0004930	G-protein coupled receptor activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0003723	RNA binding

0.84	GO:0036157	outer dynein arm
0.76	GO:0036126	sperm flagellum
0.75	GO:0009897	external side of plasma membrane
0.45	GO:0005874	microtubule
0.35	GO:0034707	chloride channel complex

tr|T1ELQ9|T1ELQ9_HELRO
Uncharacterized protein
Search

tr|T1ELR0|T1ELR0_HELRO
Uncharacterized protein
Search

CAPSL

0.96	Calcyphosine like

0.33	GO:0016310	phosphorylation
0.32	GO:0055114	oxidation-reduction process

0.70	GO:0005509	calcium ion binding
0.34	GO:0016174	NAD(P)H oxidase activity
0.33	GO:0016301	kinase activity

0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:1.6.3.1

GO:0016174

tr|T1ELR1|T1ELR1_HELRO
Uncharacterized protein
Search

RAC2

0.77	Rac small GTPase

0.77	GO:0007264	small GTPase mediated signal transduction
0.54	GO:0071593	lymphocyte aggregation
0.54	GO:0060753	regulation of mast cell chemotaxis
0.54	GO:0010592	positive regulation of lamellipodium assembly
0.54	GO:0060263	regulation of respiratory burst
0.53	GO:0090023	positive regulation of neutrophil chemotaxis
0.53	GO:0043304	regulation of mast cell degranulation
0.51	GO:1903955	positive regulation of protein targeting to mitochondrion
0.51	GO:0042129	regulation of T cell proliferation
0.51	GO:0010810	regulation of cell-substrate adhesion

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.49	GO:0019887	protein kinase regulator activity
0.36	GO:0004994	somatostatin receptor activity
0.35	GO:0019901	protein kinase binding
0.35	GO:0051022	Rho GDP-dissociation inhibitor binding
0.35	GO:0031996	thioesterase binding
0.34	GO:0051117	ATPase binding
0.34	GO:0042826	histone deacetylase binding
0.34	GO:0017137	Rab GTPase binding

0.51	GO:0005884	actin filament
0.51	GO:0030027	lamellipodium
0.48	GO:0005635	nuclear envelope
0.45	GO:0005829	cytosol
0.37	GO:0031982	vesicle
0.36	GO:0036477	somatodendritic compartment
0.36	GO:0044309	neuron spine
0.36	GO:0005925	focal adhesion
0.36	GO:0043230	extracellular organelle
0.35	GO:0098588	bounding membrane of organelle

tr|T1ELR2|T1ELR2_HELRO
NADPH:adrenodoxin oxidoreductase, mitochondrial
Search

FDXR

0.75	NADPH:adrenodoxin oxidoreductase, mitochondrial

0.52	GO:0055114	oxidation-reduction process
0.42	GO:0006744	ubiquinone biosynthetic process
0.36	GO:0006091	generation of precursor metabolites and energy
0.36	GO:0008203	cholesterol metabolic process
0.36	GO:0006879	cellular iron ion homeostasis
0.35	GO:0006694	steroid biosynthetic process
0.34	GO:0008207	C21-steroid hormone metabolic process
0.34	GO:0006739	NADP metabolic process
0.34	GO:0032259	methylation
0.33	GO:0042446	hormone biosynthetic process

0.82	GO:0015039	NADPH-adrenodoxin reductase activity
0.40	GO:0004324	ferredoxin-NADP+ reductase activity
0.39	GO:0050661	NADP binding
0.37	GO:0050660	flavin adenine dinucleotide binding
0.36	GO:0009055	electron transfer activity
0.34	GO:0008168	methyltransferase activity
0.33	GO:0003735	structural constituent of ribosome
0.32	GO:0005515	protein binding
0.32	GO:0003723	RNA binding

0.71	GO:0005759	mitochondrial matrix
0.38	GO:0031966	mitochondrial membrane
0.38	GO:0019866	organelle inner membrane
0.33	GO:0015935	small ribosomal subunit
0.30	GO:0016021	integral component of membrane

0.82

EC:1.18.1.6

GO:0015039

tr|T1ELR3|T1ELR3_HELRO
Ferritin
Search

0.56	Soma ferritin

0.76	GO:0006879	cellular iron ion homeostasis
0.75	GO:0006826	iron ion transport
0.52	GO:0055114	oxidation-reduction process
0.43	GO:0051238	sequestering of metal ion
0.41	GO:0051651	maintenance of location in cell
0.38	GO:0010106	cellular response to iron ion starvation
0.38	GO:0046427	positive regulation of JAK-STAT cascade

0.80	GO:0016724	oxidoreductase activity, oxidizing metal ions, oxygen as acceptor
0.76	GO:0008199	ferric iron binding

0.34

GO:0005737

cytoplasm

0.80

EC:1.16.3

GO:0016724

tr|T1ELR4|T1ELR4_HELRO
Uncharacterized protein
Search

RRAS2

0.74	Ras oncogene

0.61	GO:0007165	signal transduction
0.49	GO:1901214	regulation of neuron death
0.49	GO:0030335	positive regulation of cell migration
0.40	GO:0007567	parturition
0.40	GO:0040025	vulval development
0.37	GO:0001649	osteoblast differentiation
0.34	GO:0008284	positive regulation of cell proliferation

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005515	protein binding
0.34	GO:0004767	sphingomyelin phosphodiesterase activity

0.37	GO:0005925	focal adhesion
0.37	GO:0070062	extracellular exosome
0.36	GO:0005622	intracellular
0.34	GO:0005886	plasma membrane
0.33	GO:0012505	endomembrane system
0.30	GO:0016021	integral component of membrane

0.34	EC:3.1.4.12	GO:0004767
0.34	KEGG:R02541	GO:0004767

tr|T1ELR5|T1ELR5_HELRO
Uncharacterized protein
Search

XPA

0.90	DNA repair protein complementing XP-A cells

0.73	GO:0006289	nucleotide-excision repair
0.49	GO:0009411	response to UV
0.46	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage
0.46	GO:0035264	multicellular organism growth
0.45	GO:0071482	cellular response to light stimulus
0.45	GO:0036297	interstrand cross-link repair
0.44	GO:0034504	protein localization to nucleus
0.42	GO:0006979	response to oxidative stress
0.42	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.41	GO:0006284	base-excision repair

0.73	GO:0003684	damaged DNA binding
0.43	GO:0019904	protein domain specific binding
0.43	GO:0042803	protein homodimerization activity
0.35	GO:0003690	double-stranded DNA binding
0.34	GO:0046872	metal ion binding
0.34	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity
0.33	GO:0003779	actin binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005634	nucleus
0.46	GO:0045171	intercellular bridge
0.44	GO:0030894	replisome
0.42	GO:1990391	DNA repair complex
0.41	GO:0031974	membrane-enclosed lumen
0.41	GO:0043234	protein complex
0.33	GO:0015629	actin cytoskeleton
0.33	GO:0044430	cytoskeletal part
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.34

EC:2.3.1.51

GO:0003841

tr|T1ELR6|T1ELR6_HELRO
Uncharacterized protein
Search

PACSIN1

0.84	Protein kinase C and casein kinase substrate in neurons protein 2

0.66	GO:0097320	plasma membrane tubulation
0.57	GO:0048666	neuron development
0.57	GO:0007010	cytoskeleton organization
0.56	GO:0030029	actin filament-based process
0.56	GO:0030100	regulation of endocytosis
0.56	GO:0048488	synaptic vesicle endocytosis
0.56	GO:0097435	supramolecular fiber organization
0.52	GO:0051051	negative regulation of transport
0.51	GO:0016310	phosphorylation
0.51	GO:0051129	negative regulation of cellular component organization

0.53	GO:0016301	kinase activity
0.53	GO:0008289	lipid binding
0.49	GO:0042802	identical protein binding
0.48	GO:0008092	cytoskeletal protein binding
0.41	GO:0043168	anion binding
0.36	GO:0019855	calcium channel inhibitor activity
0.35	GO:0045296	cadherin binding

0.54	GO:0098590	plasma membrane region
0.53	GO:0120038	plasma membrane bounded cell projection part
0.53	GO:0045202	synapse
0.53	GO:0031256	leading edge membrane
0.53	GO:0001726	ruffle
0.52	GO:0043209	myelin sheath
0.52	GO:0030137	COPI-coated vesicle
0.47	GO:0043005	neuron projection
0.46	GO:0032154	cleavage furrow
0.46	GO:0005768	endosome

tr|T1ELR7|T1ELR7_HELRO
Uncharacterized protein
Search

ARFRP1

0.89	ADP-ribosylation factor-related protein 1

0.51	GO:0043001	Golgi to plasma membrane protein transport
0.51	GO:0034067	protein localization to Golgi apparatus
0.50	GO:0007369	gastrulation
0.49	GO:0042147	retrograde transport, endosome to Golgi
0.34	GO:0006886	intracellular protein transport
0.33	GO:0072583	clathrin-dependent endocytosis
0.33	GO:0009607	response to biotic stimulus
0.33	GO:0007165	signal transduction

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0035615	clathrin adaptor activity
0.34	GO:0003924	GTPase activity

0.49	GO:0005802	trans-Golgi network
0.45	GO:0005829	cytosol
0.35	GO:0030117	membrane coat
0.34	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1ELR8|T1ELR8_HELRO
Uncharacterized protein
Search

TTC8

0.94	Tetratricopeptide repeat protein 8

0.85	GO:1905515	non-motile cilium assembly
0.52	GO:1903251	multi-ciliated epithelial cell differentiation
0.52	GO:0060219	camera-type eye photoreceptor cell differentiation
0.52	GO:0034260	negative regulation of GTPase activity
0.52	GO:0021772	olfactory bulb development
0.52	GO:0060122	inner ear receptor cell stereocilium organization
0.51	GO:0001736	establishment of planar polarity
0.51	GO:0035264	multicellular organism growth
0.51	GO:0051492	regulation of stress fiber assembly
0.51	GO:0045444	fat cell differentiation

0.39	GO:0001103	RNA polymerase II repressing transcription factor binding
0.33	GO:0030246	carbohydrate binding

0.84	GO:0034464	BBSome
0.51	GO:0032391	photoreceptor connecting cilium
0.39	GO:0036064	ciliary basal body
0.38	GO:0005813	centrosome
0.35	GO:0060170	ciliary membrane
0.34	GO:0005814	centriole
0.30	GO:0031224	intrinsic component of membrane

tr|T1ELR9|T1ELR9_HELRO
Katanin p60 ATPase-containing subunit A1
Search

KATNA1

0.42	Katanin p60 ATPase-containing subunit A1

0.83	GO:0051013	microtubule severing
0.53	GO:0051301	cell division
0.53	GO:0007049	cell cycle
0.46	GO:0010091	trichome branching
0.46	GO:0009825	multidimensional cell growth
0.45	GO:0043622	cortical microtubule organization
0.44	GO:0009832	plant-type cell wall biogenesis
0.36	GO:0007283	spermatogenesis

0.84	GO:0008568	microtubule-severing ATPase activity
0.73	GO:0008017	microtubule binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0042802	identical protein binding

0.69	GO:0005874	microtubule
0.61	GO:0005815	microtubule organizing center
0.61	GO:0000922	spindle pole
0.47	GO:0005737	cytoplasm
0.42	GO:0005875	microtubule associated complex
0.38	GO:0005634	nucleus
0.36	GO:0030496	midbody
0.34	GO:0072686	mitotic spindle
0.30	GO:0031224	intrinsic component of membrane

0.84

EC:3.6.4.3

GO:0008568

tr|T1ELS0|T1ELS0_HELRO
Histone H2A
Search

tr|T1ELS1|T1ELS1_HELRO
Uncharacterized protein
Search

LSM2

0.80	U6 snRNA-associated Sm-like protein LSm2

0.71	GO:0000398	mRNA splicing, via spliceosome
0.38	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation
0.37	GO:0006438	valyl-tRNA aminoacylation
0.37	GO:0106074	aminoacyl-tRNA metabolism involved in translational fidelity
0.37	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.35	GO:0006402	mRNA catabolic process
0.34	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.34	GO:0046856	phosphatidylinositol dephosphorylation
0.34	GO:0022618	ribonucleoprotein complex assembly

0.56	GO:0003723	RNA binding
0.51	GO:0017160	Ral GTPase binding
0.39	GO:0000213	tRNA-intron endonuclease activity
0.37	GO:0004832	valine-tRNA ligase activity
0.37	GO:0002161	aminoacyl-tRNA editing activity
0.37	GO:0019901	protein kinase binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.78	GO:0005688	U6 snRNP
0.76	GO:0000932	P-body
0.75	GO:0046540	U4/U6 x U5 tri-snRNP complex
0.71	GO:0005681	spliceosomal complex
0.48	GO:1990726	Lsm1-7-Pat1 complex
0.44	GO:1902494	catalytic complex
0.33	GO:0019013	viral nucleocapsid
0.33	GO:0005654	nucleoplasm
0.33	GO:0005829	cytosol
0.33	GO:0031966	mitochondrial membrane

0.39	EC:3.1.27.9	GO:0000213
0.37	KEGG:R03665	GO:0004832

tr|T1ELS2|T1ELS2_HELRO
Uncharacterized protein
Search

TM2D3

0.95	TM2 domain-containing protein almondex

0.46	GO:0071897	DNA biosynthetic process
0.45	GO:0006281	DNA repair
0.34	GO:0006435	threonyl-tRNA aminoacylation
0.33	GO:0002098	tRNA wobble uridine modification
0.32	GO:0006468	protein phosphorylation

0.48	GO:0003684	damaged DNA binding
0.47	GO:0003887	DNA-directed DNA polymerase activity
0.34	GO:0004829	threonine-tRNA ligase activity
0.33	GO:0019239	deaminase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0004672	protein kinase activity

0.33	GO:0033588	Elongator holoenzyme complex
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.47

EC:2.7.7.7

GO:0003887

tr|T1ELS3|T1ELS3_HELRO
Uncharacterized protein
Search

PIP4K2A

0.83	Phosphatidylinositol-4-phosphate 5-kinase type II beta

0.75	GO:0046854	phosphatidylinositol phosphorylation
0.59	GO:2000786	positive regulation of autophagosome assembly
0.56	GO:0035855	megakaryocyte development
0.41	GO:0048634	regulation of muscle organ development
0.35	GO:0014066	regulation of phosphatidylinositol 3-kinase signaling
0.34	GO:0006661	phosphatidylinositol biosynthetic process

0.82	GO:0016307	phosphatidylinositol phosphate kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0042803	protein homodimerization activity

0.56	GO:0005776	autophagosome
0.39	GO:0005654	nucleoplasm
0.36	GO:0005886	plasma membrane
0.35	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0005829	cytosol

0.82

GO:0016307

tr|T1ELS4|T1ELS4_HELRO
Uncharacterized protein
Search

0.10	E3 ubiquitin-protein ligase CBL

0.73	GO:0016567	protein ubiquitination
0.71	GO:0007166	cell surface receptor signaling pathway
0.70	GO:0023051	regulation of signaling
0.48	GO:0061099	negative regulation of protein tyrosine kinase activity
0.46	GO:0007465	R7 cell fate commitment
0.46	GO:0008069	dorsal/ventral axis specification, ovarian follicular epithelium
0.46	GO:0048134	germ-line cyst formation
0.46	GO:0032353	negative regulation of hormone biosynthetic process
0.45	GO:0007298	border follicle cell migration
0.44	GO:0010648	negative regulation of cell communication

0.85	GO:0001784	phosphotyrosine residue binding
0.74	GO:0004842	ubiquitin-protein transferase activity
0.70	GO:0005509	calcium ion binding
0.64	GO:0004871	signal transducer activity
0.52	GO:0016874	ligase activity
0.47	GO:0030971	receptor tyrosine kinase binding
0.41	GO:0017124	SH3 domain binding
0.38	GO:0061659	ubiquitin-like protein ligase activity
0.38	GO:0046875	ephrin receptor binding
0.38	GO:0045296	cadherin binding

0.61	GO:0005634	nucleus
0.42	GO:0005938	cell cortex
0.41	GO:0045121	membrane raft
0.37	GO:0098590	plasma membrane region
0.36	GO:0005829	cytosol
0.35	GO:0098797	plasma membrane protein complex
0.33	GO:0042025	host cell nucleus

0.52	EC:6	GO:0016874
0.74	KEGG:R03876	GO:0004842

tr|T1ELS5|T1ELS5_HELRO
Uncharacterized protein
Search

0.41	GO:0006958	complement activation, classical pathway
0.40	GO:0009653	anatomical structure morphogenesis
0.39	GO:0007275	multicellular organism development
0.39	GO:0009888	tissue development
0.38	GO:0030154	cell differentiation
0.37	GO:0030198	extracellular matrix organization
0.37	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.36	GO:0048589	developmental growth
0.35	GO:0007528	neuromuscular junction development
0.35	GO:0071230	cellular response to amino acid stimulus

0.59	GO:0005201	extracellular matrix structural constituent
0.44	GO:0042302	structural constituent of cuticle
0.36	GO:0030246	carbohydrate binding
0.36	GO:0048407	platelet-derived growth factor binding
0.35	GO:0030414	peptidase inhibitor activity
0.34	GO:0046332	SMAD binding
0.34	GO:0005178	integrin binding
0.34	GO:0002020	protease binding
0.33	GO:0061135	endopeptidase regulator activity
0.32	GO:0008641	ubiquitin-like modifier activating enzyme activity

0.71	GO:0005581	collagen trimer
0.47	GO:0005576	extracellular region
0.36	GO:0099081	supramolecular polymer
0.35	GO:0005788	endoplasmic reticulum lumen
0.34	GO:0031594	neuromuscular junction
0.33	GO:0031982	vesicle
0.30	GO:0016020	membrane

tr|T1ELS6|T1ELS6_HELRO
Uncharacterized protein
Search

0.24	Putative: flagellar/basal body protein [Chlamydomonas reinhardtii]

0.38

GO:0006464

cellular protein modification process

0.76	GO:0031514	motile cilium
0.30	GO:0031224	intrinsic component of membrane

tr|T1ELS7|T1ELS7_HELRO
Uncharacterized protein
Search

UBE2C

0.75	Cyclin-selective ubiquitin carrier protein E2-C

0.53	GO:0031145	anaphase-promoting complex-dependent catabolic process
0.51	GO:0010458	exit from mitosis
0.50	GO:0007088	regulation of mitotic nuclear division
0.50	GO:0000209	protein polyubiquitination
0.50	GO:1901990	regulation of mitotic cell cycle phase transition
0.49	GO:0010994	free ubiquitin chain polymerization
0.48	GO:0051785	positive regulation of nuclear division
0.48	GO:1901989	positive regulation of cell cycle phase transition
0.48	GO:1902099	regulation of metaphase/anaphase transition of cell cycle
0.48	GO:1905818	regulation of chromosome separation

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.50	GO:0061631	ubiquitin conjugating enzyme activity
0.49	GO:0044389	ubiquitin-like protein ligase binding
0.44	GO:0061630	ubiquitin protein ligase activity
0.35	GO:0016874	ligase activity
0.33	GO:0005200	structural constituent of cytoskeleton
0.33	GO:0017111	nucleoside-triphosphatase activity
0.33	GO:0032550	purine ribonucleoside binding

0.46	GO:0000151	ubiquitin ligase complex
0.43	GO:0005634	nucleus
0.41	GO:0005829	cytosol
0.40	GO:0031616	spindle pole centrosome
0.38	GO:0005886	plasma membrane
0.33	GO:0005874	microtubule
0.33	GO:0031974	membrane-enclosed lumen
0.30	GO:0016021	integral component of membrane

0.35

EC:6

GO:0016874

tr|T1ELS8|T1ELS8_HELRO
Uncharacterized protein
Search

tr|T1ELS9|T1ELS9_HELRO
Uncharacterized protein
Search

GAD1

0.53	Glutamate decarboxylase

0.57	GO:0019752	carboxylic acid metabolic process
0.53	GO:0035641	locomotory exploration behavior
0.52	GO:0035176	social behavior
0.45	GO:0042136	neurotransmitter biosynthetic process
0.39	GO:0051932	synaptic transmission, GABAergic
0.38	GO:0016053	organic acid biosynthetic process
0.37	GO:0042493	response to drug
0.36	GO:1901566	organonitrogen compound biosynthetic process
0.35	GO:0018352	protein-pyridoxal-5-phosphate linkage
0.34	GO:0099643	signal release from synapse

0.68	GO:0016831	carboxy-lyase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.40	GO:0016595	glutamate binding
0.39	GO:0047485	protein N-terminus binding
0.37	GO:0046982	protein heterodimerization activity

0.54	GO:0060077	inhibitory synapse
0.51	GO:0043679	axon terminus
0.51	GO:0048786	presynaptic active zone
0.51	GO:0030424	axon
0.48	GO:0005938	cell cortex
0.42	GO:0005739	mitochondrion
0.37	GO:0008021	synaptic vesicle
0.37	GO:0043025	neuronal cell body
0.35	GO:0061200	clathrin-sculpted gamma-aminobutyric acid transport vesicle
0.34	GO:0030665	clathrin-coated vesicle membrane

0.68

EC:4.1.1

GO:0016831

tr|T1ELT0|T1ELT0_HELRO
Uncharacterized protein
Search

PSMB1

0.53	Proteasome subunit beta type

0.72	GO:0051603	proteolysis involved in cellular protein catabolic process
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.35	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation
0.35	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0070498	interleukin-1-mediated signaling pathway

0.77	GO:0070003	threonine-type peptidase activity
0.65	GO:0004175	endopeptidase activity
0.33	GO:0005515	protein binding

0.76	GO:0005839	proteasome core complex
0.59	GO:0005634	nucleus
0.47	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.35	GO:0031983	vesicle lumen
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0097708	intracellular vesicle
0.33	GO:0044446	intracellular organelle part
0.33	GO:0012505	endomembrane system

tr|T1ELT1|T1ELT1_HELRO
Uncharacterized protein
Search

BTBD2

0.93	BTB domain containing 2

0.68	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.64	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.63	GO:0022008	neurogenesis
0.62	GO:0030162	regulation of proteolysis

0.65

GO:0031625

ubiquitin protein ligase binding

0.76	GO:0000932	P-body
0.68	GO:0019005	SCF ubiquitin ligase complex
0.58	GO:0005829	cytosol

tr|T1ELT2|T1ELT2_HELRO
Uncharacterized protein
Search

0.62	Troponin C

0.70

GO:0005509

calcium ion binding

tr|T1ELT3|T1ELT3_HELRO
Uncharacterized protein
Search

DNAL4

0.94	Outer arm dynein light chain 4

0.72	GO:0007017	microtubule-based process
0.49	GO:2000580	regulation of ATP-dependent microtubule motor activity, plus-end-directed
0.49	GO:2000576	positive regulation of microtubule motor activity
0.47	GO:0032781	positive regulation of ATPase activity
0.35	GO:0006928	movement of cell or subcellular component
0.34	GO:0007009	plasma membrane organization

0.49	GO:0051959	dynein light intermediate chain binding
0.48	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed
0.48	GO:0045505	dynein intermediate chain binding
0.43	GO:0008092	cytoskeletal protein binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.79	GO:0030286	dynein complex
0.37	GO:0005929	cilium
0.36	GO:0005874	microtubule
0.34	GO:0106094	nuclear membrane microtubule tethering complex
0.34	GO:0034992	microtubule organizing center attachment site
0.34	GO:0031229	intrinsic component of nuclear inner membrane
0.33	GO:0031301	integral component of organelle membrane
0.33	GO:0005737	cytoplasm
0.32	GO:0005886	plasma membrane

0.48

EC:3.6.4.4

GO:0008574

tr|T1ELT4|T1ELT4_HELRO
Uncharacterized protein
Search

PARK7

0.95	Parkinsonism associated deglycase

0.80	GO:0036530	protein deglycation, methylglyoxal removal
0.79	GO:0140041	cellular detoxification of methylglyoxal
0.79	GO:0106044	guanine deglycation
0.79	GO:2000277	positive regulation of oxidative phosphorylation uncoupler activity
0.77	GO:0033864	positive regulation of NAD(P)H oxidase activity
0.77	GO:1903189	glyoxal metabolic process
0.77	GO:0036471	cellular response to glyoxal
0.76	GO:0010273	detoxification of copper ion
0.76	GO:0018323	enzyme active site formation via L-cysteine sulfinic acid
0.76	GO:1903178	positive regulation of tyrosine 3-monooxygenase activity

0.76	GO:0036470	tyrosine 3-monooxygenase activator activity
0.76	GO:0036478	L-dopa decarboxylase activator activity
0.73	GO:0044388	small protein activating enzyme binding
0.73	GO:1903135	cupric ion binding
0.72	GO:0016532	superoxide dismutase copper chaperone activity
0.72	GO:1903136	cuprous ion binding
0.72	GO:1990381	ubiquitin-specific protease binding
0.71	GO:0050681	androgen receptor binding
0.70	GO:0036524	protein deglycase activity
0.70	GO:0097110	scaffold protein binding

0.68	GO:0016605	PML body
0.67	GO:0005913	cell-cell adherens junction
0.66	GO:0005747	mitochondrial respiratory chain complex I
0.65	GO:0044297	cell body
0.65	GO:0098793	presynapse
0.64	GO:0005758	mitochondrial intermembrane space
0.64	GO:0048471	perinuclear region of cytoplasm
0.63	GO:0043005	neuron projection
0.62	GO:0005759	mitochondrial matrix
0.59	GO:0000785	chromatin

0.61

EC:1.11.1.15

GO:0051920

tr|T1ELT5|T1ELT5_HELRO
Uncharacterized protein
Search

0.78	Putative pattern-formation protein/guanine nucleotide exchange factor

0.81	GO:0032012	regulation of ARF protein signal transduction
0.66	GO:0065009	regulation of molecular function
0.42	GO:0008586	imaginal disc-derived wing vein morphogenesis
0.42	GO:0040018	positive regulation of multicellular organism growth
0.42	GO:0001700	embryonic development via the syncytial blastoderm
0.41	GO:0030100	regulation of endocytosis
0.41	GO:0110020	regulation of actomyosin structure organization
0.41	GO:0043410	positive regulation of MAPK cascade
0.41	GO:0016331	morphogenesis of embryonic epithelium
0.36	GO:0046579	positive regulation of Ras protein signal transduction

0.82	GO:0005086	ARF guanyl-nucleotide exchange factor activity
0.42	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.40	GO:0042803	protein homodimerization activity
0.35	GO:0003743	translation initiation factor activity
0.34	GO:0034450	ubiquitin-ubiquitin ligase activity
0.34	GO:0008061	chitin binding
0.33	GO:0016791	phosphatase activity
0.33	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds

0.43	GO:1904269	cell leading edge cell cortex
0.42	GO:0032154	cleavage furrow
0.41	GO:0070938	contractile ring
0.41	GO:0005913	cell-cell adherens junction
0.36	GO:0005886	plasma membrane
0.35	GO:0005852	eukaryotic translation initiation factor 3 complex
0.35	GO:0000139	Golgi membrane
0.34	GO:0005829	cytosol
0.34	GO:0000151	ubiquitin ligase complex
0.33	GO:0005576	extracellular region

0.33

EC:3.1.3 EC:3.1.3.41

GO:0016791

tr|T1ELT6|T1ELT6_HELRO
Uncharacterized protein
Search

TTLL1

0.89	Tubulin polyglutamylase TTLL1

0.85	GO:0018095	protein polyglutamylation
0.50	GO:0097724	sperm flagellum movement
0.48	GO:0060294	cilium movement involved in cell motility
0.48	GO:0007288	sperm axoneme assembly
0.48	GO:0003351	epithelial cilium movement

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0070740	tubulin-glutamic acid ligase activity
0.34	GO:0005515	protein binding
0.33	GO:0003677	DNA binding

0.40	GO:0005874	microtubule
0.35	GO:0005829	cytosol

0.43

EC:6.3.2

GO:0070740

tr|T1ELT7|T1ELT7_HELRO
Uncharacterized protein
Search

0.40	Collagen triple helix repeat-containing protein

0.48	GO:0032836	glomerular basement membrane development
0.41	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.39	GO:0052547	regulation of peptidase activity
0.39	GO:0032963	collagen metabolic process
0.38	GO:0032268	regulation of cellular protein metabolic process
0.38	GO:0051346	negative regulation of hydrolase activity
0.37	GO:2000026	regulation of multicellular organismal development
0.37	GO:0034505	tooth mineralization
0.37	GO:0051276	chromosome organization
0.37	GO:0048519	negative regulation of biological process

0.78	GO:0005201	extracellular matrix structural constituent
0.38	GO:0030414	peptidase inhibitor activity
0.37	GO:0048407	platelet-derived growth factor binding
0.36	GO:0002020	protease binding
0.36	GO:0005178	integrin binding
0.35	GO:0042802	identical protein binding
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0042302	structural constituent of cuticle
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.78	GO:0005581	collagen trimer
0.71	GO:0044420	extracellular matrix component
0.66	GO:0005578	proteinaceous extracellular matrix
0.45	GO:0099081	supramolecular polymer
0.37	GO:0005694	chromosome
0.36	GO:0031594	neuromuscular junction
0.36	GO:0005783	endoplasmic reticulum
0.35	GO:0005615	extracellular space
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part

tr|T1ELT8|T1ELT8_HELRO
Uncharacterized protein
Search

0.67	Ubiquitin modifier-activating enzyme

0.60	GO:0036211	protein modification process
0.56	GO:0044267	cellular protein metabolic process
0.40	GO:0035096	larval midgut cell programmed cell death
0.39	GO:0016322	neuron remodeling
0.39	GO:0016319	mushroom body development
0.39	GO:0030707	ovarian follicle cell development
0.39	GO:0019915	lipid storage
0.39	GO:0044248	cellular catabolic process
0.38	GO:0061919	process utilizing autophagic mechanism
0.38	GO:0042593	glucose homeostasis

0.76	GO:0008641	ubiquitin-like modifier activating enzyme activity
0.52	GO:0032559	adenyl ribonucleotide binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0000287	magnesium ion binding
0.34	GO:0003910	DNA ligase (ATP) activity
0.34	GO:0016881	acid-amino acid ligase activity
0.33	GO:0016407	acetyltransferase activity
0.33	GO:0015078	hydrogen ion transmembrane transporter activity
0.32	GO:0003677	DNA binding

0.50	GO:0005634	nucleus
0.42	GO:0005737	cytoplasm
0.38	GO:0030425	dendrite
0.34	GO:0033180	proton-transporting V-type ATPase, V1 domain
0.30	GO:0016021	integral component of membrane

0.34

EC:6.5.1.1

GO:0003910

tr|T1ELT9|T1ELT9_HELRO
Sodium/potassium-transporting ATPase subunit alpha
Search

0.64	Sodium/potassium-transporting ATPase subunit alpha

0.85	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient
0.76	GO:0090662	ATP hydrolysis coupled transmembrane transport
0.73	GO:0006814	sodium ion transport
0.71	GO:0006813	potassium ion transport
0.42	GO:0007630	jump response
0.42	GO:0035158	regulation of tube diameter, open tracheal system
0.42	GO:0060439	trachea morphogenesis
0.42	GO:0019991	septate junction assembly
0.42	GO:0051124	synaptic growth at neuromuscular junction
0.41	GO:0001700	embryonic development via the syncytial blastoderm

0.85	GO:0005391	sodium:potassium-exchanging ATPase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0046872	metal ion binding
0.33	GO:0016301	kinase activity

0.41	GO:0005918	septate junction
0.40	GO:0016323	basolateral plasma membrane
0.36	GO:0005634	nucleus
0.35	GO:0005890	sodium:potassium-exchanging ATPase complex
0.35	GO:0042383	sarcolemma
0.32	GO:0005737	cytoplasm

0.85

EC:3.6.3.9

GO:0005391

tr|T1ELU0|T1ELU0_HELRO
Uncharacterized protein
Search

0.11	39S ribosomal protein L27

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process

0.64

GO:0003735

structural constituent of ribosome

0.61

GO:0005840

ribosome

tr|T1ELU1|T1ELU1_HELRO
Uncharacterized protein
Search

RPL23

0.59	Large subunit ribosomal protein L23e

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.41	GO:0072717	cellular response to actinomycin D
0.40	GO:2000059	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.40	GO:1901798	positive regulation of signal transduction by p53 class mediator
0.40	GO:1904667	negative regulation of ubiquitin protein ligase activity
0.40	GO:0071157	negative regulation of cell cycle arrest
0.40	GO:0071158	positive regulation of cell cycle arrest

0.64	GO:0003735	structural constituent of ribosome
0.44	GO:0017022	myosin binding
0.41	GO:1990948	ubiquitin ligase inhibitor activity
0.40	GO:0001223	transcription coactivator binding
0.39	GO:0070180	large ribosomal subunit rRNA binding
0.38	GO:0031625	ubiquitin protein ligase binding

0.61	GO:0005840	ribosome
0.39	GO:0005730	nucleolus
0.38	GO:0044445	cytosolic part
0.37	GO:0005654	nucleoplasm
0.35	GO:0043234	protein complex
0.34	GO:0005925	focal adhesion
0.34	GO:0070062	extracellular exosome
0.34	GO:0031012	extracellular matrix
0.30	GO:0031224	intrinsic component of membrane

tr|T1ELU2|T1ELU2_HELRO
Uncharacterized protein
Search

0.54	Corepressor interacting with RBPJ

0.65	GO:0045892	negative regulation of transcription, DNA-templated
0.46	GO:0022900	electron transport chain
0.44	GO:0008380	RNA splicing
0.43	GO:0006397	mRNA processing
0.39	GO:0006357	regulation of transcription by RNA polymerase II
0.39	GO:0006351	transcription, DNA-templated
0.37	GO:0045893	positive regulation of transcription, DNA-templated

0.70	GO:0019901	protein kinase binding
0.47	GO:0020037	heme binding
0.46	GO:0009055	electron transfer activity
0.43	GO:0046872	metal ion binding
0.39	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.39	GO:0042826	histone deacetylase binding
0.38	GO:0003714	transcription corepressor activity
0.34	GO:0003676	nucleic acid binding

0.73	GO:0000118	histone deacetylase complex
0.72	GO:0016607	nuclear speck
0.70	GO:0005813	centrosome
0.55	GO:0043234	protein complex
0.35	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|T1ELU3|T1ELU3_HELRO
Uncharacterized protein
Search

0.61	Centromere protein B

0.34	GO:0070932	histone H3 deacetylation
0.32	GO:0006351	transcription, DNA-templated
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.34	GO:0032041	NAD-dependent histone deacetylase activity (H3-K14 specific)
0.33	GO:0005515	protein binding

0.37	GO:0030425	dendrite
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.34

EC:3.5.1.98

GO:0032041

tr|T1ELU4|T1ELU4_HELRO
Uncharacterized protein
Search

tr|T1ELU5|T1ELU5_HELRO
Uncharacterized protein
Search

0.66	Spectrin alpha chain, non-erythrocytic

0.70	GO:0005509	calcium ion binding
0.41	GO:0045296	cadherin binding

0.39	GO:0015630	microtubule cytoskeleton
0.36	GO:0043231	intracellular membrane-bounded organelle

tr|T1ELU6|T1ELU6_HELRO
Uncharacterized protein
Search

PA2G4

0.54	Metallopeptidase

0.42	GO:0045597	positive regulation of cell differentiation
0.42	GO:0043066	negative regulation of apoptotic process
0.40	GO:0045892	negative regulation of transcription, DNA-templated
0.39	GO:0006417	regulation of translation
0.38	GO:0006364	rRNA processing
0.37	GO:0043312	neutrophil degranulation
0.37	GO:0045116	protein neddylation
0.37	GO:0007050	cell cycle arrest
0.36	GO:0008283	cell proliferation
0.36	GO:0006351	transcription, DNA-templated

0.42	GO:0031625	ubiquitin protein ligase binding
0.38	GO:0003700	DNA binding transcription factor activity
0.37	GO:0004177	aminopeptidase activity
0.37	GO:0019781	NEDD8 activating enzyme activity
0.36	GO:0003723	RNA binding
0.36	GO:0003677	DNA binding
0.36	GO:0046872	metal ion binding
0.35	GO:0016881	acid-amino acid ligase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding

0.48	GO:0005737	cytoplasm
0.42	GO:0005730	nucleolus
0.39	GO:0070062	extracellular exosome
0.37	GO:0031983	vesicle lumen
0.37	GO:0030529	intracellular ribonucleoprotein complex
0.35	GO:0097708	intracellular vesicle
0.35	GO:0012505	endomembrane system
0.30	GO:0016020	membrane

0.37

EC:3.4.11

GO:0004177

tr|T1ELU7|T1ELU7_HELRO
Uncharacterized protein
Search

RAB18

0.84	Putative rab subfamily protein of small gtpase

0.53	GO:0034389	lipid particle organization
0.47	GO:0071786	endoplasmic reticulum tubular network organization
0.41	GO:0051170	nuclear import
0.41	GO:0001654	eye development
0.40	GO:0007420	brain development
0.38	GO:0015031	protein transport
0.36	GO:0043009	chordate embryonic development
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0007264	small GTPase mediated signal transduction
0.33	GO:0006397	mRNA processing

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0004767	sphingomyelin phosphodiesterase activity
0.33	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.46	GO:0071782	endoplasmic reticulum tubular network
0.44	GO:0005794	Golgi apparatus
0.35	GO:0070062	extracellular exosome
0.34	GO:0009925	basal plasma membrane
0.34	GO:0030667	secretory granule membrane
0.34	GO:0016324	apical plasma membrane
0.33	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0005829	cytosol
0.32	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.34	EC:3.1.4.12	GO:0004767
0.34	KEGG:R02541	GO:0004767

tr|T1ELU8|T1ELU8_HELRO
Uncharacterized protein
Search

VPS25

0.65	WNK lysine deficient protein kinase 4

0.81	GO:0071985	multivesicular body sorting pathway
0.51	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity
0.47	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
0.47	GO:0045324	late endosome to vacuole transport
0.47	GO:0072666	establishment of protein localization to vacuole
0.42	GO:0006886	intracellular protein transport
0.37	GO:0006468	protein phosphorylation
0.37	GO:0070294	renal sodium ion absorption
0.35	GO:0036258	multivesicular body assembly
0.35	GO:0006351	transcription, DNA-templated

0.50	GO:0047485	protein N-terminus binding
0.49	GO:0042803	protein homodimerization activity
0.40	GO:0005198	structural molecule activity
0.38	GO:0004674	protein serine/threonine kinase activity
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0035299	inositol pentakisphosphate 2-kinase activity
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding

0.83	GO:0000814	ESCRT II complex
0.44	GO:0005829	cytosol
0.41	GO:0005634	nucleus
0.36	GO:0070062	extracellular exosome
0.34	GO:0005739	mitochondrion
0.33	GO:0043233	organelle lumen

0.38	EC:2.7.11	GO:0004674
0.36	KEGG:R05202	GO:0035299

tr|T1ELU9|T1ELU9_HELRO
Uncharacterized protein
Search

HSPE1

0.85	Heat shock protein, mitochondrial

0.69	GO:0006457	protein folding
0.46	GO:0006986	response to unfolded protein
0.35	GO:0001649	osteoblast differentiation
0.34	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.32	GO:0016310	phosphorylation

0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0051087	chaperone binding
0.43	GO:0051082	unfolded protein binding
0.37	GO:0046872	metal ion binding
0.33	GO:0003723	RNA binding
0.32	GO:0016301	kinase activity

0.49	GO:0005737	cytoplasm
0.42	GO:0031974	membrane-enclosed lumen
0.40	GO:0043231	intracellular membrane-bounded organelle
0.39	GO:0044446	intracellular organelle part
0.35	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

tr|T1ELV0|T1ELV0_HELRO
Uncharacterized protein
Search

0.89	Barrier-to-autointegration factor A

0.50	GO:0045071	negative regulation of viral genome replication
0.42	GO:0030717	karyosome formation
0.39	GO:0030261	chromosome condensation
0.35	GO:0075713	establishment of integrated proviral latency
0.35	GO:0015074	DNA integration
0.35	GO:0007077	mitotic nuclear envelope disassembly
0.35	GO:0010951	negative regulation of endopeptidase activity
0.34	GO:0007084	mitotic nuclear envelope reassembly
0.34	GO:0051169	nuclear transport
0.34	GO:0009615	response to virus

0.55	GO:0003677	DNA binding
0.53	GO:0097726	LEM domain binding
0.49	GO:0047485	protein N-terminus binding
0.48	GO:0008022	protein C-terminus binding
0.46	GO:0042803	protein homodimerization activity
0.44	GO:0019899	enzyme binding
0.35	GO:0004869	cysteine-type endopeptidase inhibitor activity

0.46	GO:0005654	nucleoplasm
0.43	GO:0005829	cytosol
0.42	GO:0005635	nuclear envelope
0.38	GO:0005694	chromosome
0.35	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

tr|T1ELV1|T1ELV1_HELRO
Uncharacterized protein
Search

0.80	GO:0048574	long-day photoperiodism, flowering
0.80	GO:0048235	pollen sperm cell differentiation
0.53	GO:0043044	ATP-dependent chromatin remodeling
0.43	GO:0016569	covalent chromatin modification
0.38	GO:0007010	cytoskeleton organization
0.37	GO:0006508	proteolysis
0.35	GO:0005975	carbohydrate metabolic process

0.39	GO:0070001	aspartic-type peptidase activity
0.39	GO:0005200	structural constituent of cytoskeleton
0.38	GO:0004175	endopeptidase activity
0.36	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.36	GO:0005515	protein binding

0.66	GO:0005730	nucleolus
0.55	GO:0071564	npBAF complex
0.36	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.36

EC:3.2.1

GO:0004553

tr|T1ELV2|T1ELV2_HELRO
Uncharacterized protein
Search

BRK1

0.97	Syntaxin interacting protein 1

0.75	GO:0007015	actin filament organization
0.52	GO:0010592	positive regulation of lamellipodium assembly
0.48	GO:0008064	regulation of actin polymerization or depolymerization
0.47	GO:0016601	Rac protein signal transduction
0.47	GO:0070207	protein homotrimerization
0.46	GO:0048870	cell motility
0.45	GO:0001701	in utero embryonic development
0.45	GO:0021551	central nervous system morphogenesis
0.44	GO:0008284	positive regulation of cell proliferation
0.44	GO:0051491	positive regulation of filopodium assembly

0.75	GO:0032403	protein complex binding
0.46	GO:0048365	Rac GTPase binding
0.34	GO:0042802	identical protein binding
0.32	GO:0003723	RNA binding
0.32	GO:0046872	metal ion binding

0.85	GO:0031209	SCAR complex
0.45	GO:0030027	lamellipodium
0.37	GO:0005856	cytoskeleton
0.36	GO:0070062	extracellular exosome
0.34	GO:0071203	WASH complex
0.34	GO:0005681	spliceosomal complex
0.33	GO:0005829	cytosol
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1ELV3|T1ELV3_HELRO
Aspartate aminotransferase
Search

GOT2

0.49	Aspartate aminotransferase

0.59	GO:0006520	cellular amino acid metabolic process
0.48	GO:0009058	biosynthetic process
0.47	GO:0043649	dicarboxylic acid catabolic process
0.45	GO:0045471	response to ethanol
0.44	GO:0015908	fatty acid transport
0.43	GO:0006103	2-oxoglutarate metabolic process
0.42	GO:1901565	organonitrogen compound catabolic process
0.41	GO:0006107	oxaloacetate metabolic process
0.40	GO:0006106	fumarate metabolic process
0.37	GO:0042537	benzene-containing compound metabolic process

0.81	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity
0.77	GO:0070546	L-phenylalanine aminotransferase activity
0.66	GO:0030170	pyridoxal phosphate binding
0.40	GO:0016212	kynurenine-oxoglutarate transaminase activity
0.34	GO:0042803	protein homodimerization activity
0.34	GO:0090729	toxin activity
0.33	GO:0004252	serine-type endopeptidase activity

0.41	GO:0043209	myelin sheath
0.41	GO:0005739	mitochondrion
0.38	GO:0005886	plasma membrane
0.37	GO:0044446	intracellular organelle part
0.37	GO:0031090	organelle membrane
0.37	GO:0031975	envelope
0.36	GO:0070013	intracellular organelle lumen
0.33	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.81	EC:2.6.1.1	GO:0004069
0.81	KEGG:R00355	GO:0004069

tr|T1ELV4|T1ELV4_HELRO
Uncharacterized protein
Search

PPP5C

0.37	Serine/threonine-protein phosphatase PP-V

0.72	GO:0006470	protein dephosphorylation
0.42	GO:0000278	mitotic cell cycle
0.40	GO:0045920	negative regulation of exocytosis
0.38	GO:0033365	protein localization to organelle

0.72	GO:0004721	phosphoprotein phosphatase activity
0.40	GO:0051879	Hsp90 protein binding
0.32	GO:0046872	metal ion binding

0.39	GO:0005634	nucleus
0.39	GO:0072686	mitotic spindle
0.36	GO:0005737	cytoplasm
0.35	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

0.72

GO:0004721

tr|T1ELV5|T1ELV5_HELRO
Uncharacterized protein
Search

0.52	3-hydroxyisobutyrate dehydrogenase

0.78	GO:0006574	valine catabolic process
0.52	GO:0055114	oxidation-reduction process
0.34	GO:0006044	N-acetylglucosamine metabolic process
0.33	GO:0005975	carbohydrate metabolic process

0.82	GO:0008442	3-hydroxyisobutyrate dehydrogenase activity
0.75	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity
0.67	GO:0051287	NAD binding
0.34	GO:0004342	glucosamine-6-phosphate deaminase activity

0.35	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.82	EC:1.1.1.31	GO:0008442
0.34	KEGG:R00765	GO:0004342

tr|T1ELV6|T1ELV6_HELRO
Uncharacterized protein
Search

AP2M1

0.82	AP-2 complex subunit mu-A

0.69	GO:0006886	intracellular protein transport
0.69	GO:0016192	vesicle-mediated transport
0.43	GO:0098657	import into cell
0.42	GO:0033227	dsRNA transport
0.38	GO:0097494	regulation of vesicle size
0.38	GO:1900244	positive regulation of synaptic vesicle endocytosis
0.38	GO:1903077	negative regulation of protein localization to plasma membrane
0.38	GO:0002092	positive regulation of receptor internalization
0.37	GO:0016050	vesicle organization
0.37	GO:0036465	synaptic vesicle recycling

0.71	GO:0008289	lipid binding
0.49	GO:0097718	disordered domain specific binding
0.39	GO:0008565	protein transporter activity
0.39	GO:0050750	low-density lipoprotein particle receptor binding
0.38	GO:0005048	signal sequence binding
0.37	GO:0044325	ion channel binding
0.34	GO:0035615	clathrin adaptor activity
0.34	GO:0004222	metalloendopeptidase activity
0.34	GO:0008270	zinc ion binding

0.79	GO:0030131	clathrin adaptor complex
0.46	GO:0005905	clathrin-coated pit
0.44	GO:0030128	clathrin coat of endocytic vesicle
0.41	GO:0005886	plasma membrane
0.40	GO:0005739	mitochondrion
0.37	GO:0043195	terminal bouton
0.36	GO:0044421	extracellular region part
0.35	GO:0036020	endolysosome membrane
0.34	GO:0030141	secretory granule
0.33	GO:0005829	cytosol

0.34

GO:0004222

tr|T1ELV7|T1ELV7_HELRO
Uncharacterized protein
Search

BUB3

0.72	Budding uninhibited by benzimidazoles 3 homolog

0.76	GO:0008608	attachment of spindle microtubules to kinetochore
0.74	GO:0051983	regulation of chromosome segregation
0.70	GO:1903047	mitotic cell cycle process
0.67	GO:0000819	sister chromatid segregation
0.67	GO:0000280	nuclear division
0.65	GO:0071173	spindle assembly checkpoint
0.64	GO:0045839	negative regulation of mitotic nuclear division
0.63	GO:2001251	negative regulation of chromosome organization
0.63	GO:1901991	negative regulation of mitotic cell cycle phase transition
0.48	GO:0051321	meiotic cell cycle

0.64	GO:0043130	ubiquitin binding
0.38	GO:0043565	sequence-specific DNA binding

0.77	GO:0000776	kinetochore
0.71	GO:1990298	bub1-bub3 complex
0.69	GO:0033597	mitotic checkpoint complex
0.64	GO:0005654	nucleoplasm
0.48	GO:0000779	condensed chromosome, centromeric region
0.37	GO:0005829	cytosol

tr|T1ELV8|T1ELV8_HELRO
Uncharacterized protein
Search

RARA

0.34	Replication-associated recombination protein A

0.66	GO:0006260	DNA replication
0.52	GO:0032392	DNA geometric change
0.52	GO:0006281	DNA repair
0.49	GO:0006310	DNA recombination
0.37	GO:0022616	DNA strand elongation
0.37	GO:0006282	regulation of DNA repair
0.36	GO:0043085	positive regulation of catalytic activity
0.35	GO:0097428	protein maturation by iron-sulfur cluster transfer
0.34	GO:0016569	covalent chromatin modification
0.34	GO:0016070	RNA metabolic process

0.55	GO:0009378	four-way junction helicase activity
0.55	GO:0003677	DNA binding
0.51	GO:0032559	adenyl ribonucleotide binding
0.50	GO:0008144	drug binding
0.50	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0043142	single-stranded DNA-dependent ATPase activity
0.36	GO:0008047	enzyme activator activity
0.34	GO:0051536	iron-sulfur cluster binding
0.34	GO:0005198	structural molecule activity
0.33	GO:0004402	histone acetyltransferase activity

0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.33

GO:0004402

tr|T1ELV9|T1ELV9_HELRO
MICOS complex subunit
Search

0.39	MICOS complex subunit

0.85

GO:0042407

cristae formation

0.83

GO:0061617

MICOS complex

tr|T1ELW0|T1ELW0_HELRO
Uncharacterized protein
Search

0.33	O-sialoglycoprotein endopeptidase

0.63	GO:0006468	protein phosphorylation
0.46	GO:0070525	tRNA threonylcarbamoyladenosine metabolic process
0.44	GO:0000722	telomere maintenance via recombination
0.41	GO:0045944	positive regulation of transcription by RNA polymerase II
0.35	GO:0034660	ncRNA metabolic process
0.35	GO:0006396	RNA processing
0.34	GO:0032259	methylation
0.34	GO:0042254	ribosome biogenesis
0.33	GO:0009059	macromolecule biosynthetic process
0.33	GO:0044249	cellular biosynthetic process

0.70	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0008168	methyltransferase activity
0.33	GO:0008234	cysteine-type peptidase activity
0.33	GO:0046872	metal ion binding
0.33	GO:0004825	methionine-tRNA ligase activity
0.32	GO:0005515	protein binding
0.32	GO:0016887	ATPase activity

0.49	GO:0000408	EKC/KEOPS complex
0.40	GO:0005829	cytosol
0.38	GO:0005634	nucleus
0.35	GO:0000781	chromosome, telomeric region
0.34	GO:0005794	Golgi apparatus
0.34	GO:0005739	mitochondrion
0.33	GO:0043233	organelle lumen
0.30	GO:0016020	membrane

0.70

GO:0004674

tr|T1ELW1|T1ELW1_HELRO
Uncharacterized protein
Search

0.58	Tripartite motif-containing protein 2

0.33	GO:0006508	proteolysis
0.33	GO:0042908	xenobiotic transport
0.33	GO:0006855	drug transmembrane transport

0.62	GO:0008270	zinc ion binding
0.34	GO:0004252	serine-type endopeptidase activity
0.33	GO:0008559	xenobiotic transmembrane transporting ATPase activity
0.32	GO:0003676	nucleic acid binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.45	GO:0005622	intracellular
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0004252

tr|T1ELW2|T1ELW2_HELRO
Uncharacterized protein
Search

ARMC4

0.73	Armadillo repeat-containing protein 4

0.74	GO:0003356	regulation of cilium beat frequency
0.74	GO:0036158	outer dynein arm assembly
0.72	GO:0021591	ventricular system development
0.71	GO:0007368	determination of left/right symmetry
0.70	GO:0003341	cilium movement
0.67	GO:0007507	heart development
0.34	GO:0006351	transcription, DNA-templated
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:0010468	regulation of gene expression

0.35	GO:0003700	DNA binding transcription factor activity
0.34	GO:0003677	DNA binding

0.72	GO:0097546	ciliary base
0.68	GO:0005930	axoneme
0.47	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

tr|T1ELW3|T1ELW3_HELRO
Uncharacterized protein
Search

TMCO1

0.90	Calcium load-activated calcium channel

0.81	GO:0032469	endoplasmic reticulum calcium ion homeostasis
0.72	GO:0070588	calcium ion transmembrane transport
0.42	GO:0006983	ER overload response

0.74

GO:0005262

calcium channel activity

0.73	GO:0030176	integral component of endoplasmic reticulum membrane
0.39	GO:0000139	Golgi membrane

tr|T1ELW4|T1ELW4_HELRO
Uncharacterized protein
Search

tr|T1ELW5|T1ELW5_HELRO
Uncharacterized protein
Search

TMEM50A

0.94	Transmembrane protein 50A

0.46	GO:0005783	endoplasmic reticulum
0.30	GO:0044425	membrane part

tr|T1ELW6|T1ELW6_HELRO
V-type proton ATPase subunit C
Search

ATP6V1C1

0.67	V-type proton ATPase subunit C

0.75	GO:0015991	ATP hydrolysis coupled proton transport
0.38	GO:0030177	positive regulation of Wnt signaling pathway
0.35	GO:0090383	phagosome acidification
0.35	GO:0033572	transferrin transport
0.34	GO:0008286	insulin receptor signaling pathway
0.34	GO:0016241	regulation of macroautophagy
0.32	GO:0007186	G-protein coupled receptor signaling pathway

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.53	GO:0036442	proton-exporting ATPase activity
0.51	GO:0015662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
0.43	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
0.36	GO:0046983	protein dimerization activity
0.33	GO:0004930	G-protein coupled receptor activity

0.80	GO:0033180	proton-transporting V-type ATPase, V1 domain
0.46	GO:0016471	vacuolar proton-transporting V-type ATPase complex
0.46	GO:0005765	lysosomal membrane
0.40	GO:0005886	plasma membrane
0.37	GO:0045177	apical part of cell
0.36	GO:0031410	cytoplasmic vesicle
0.35	GO:0070062	extracellular exosome
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|T1ELW7|T1ELW7_HELRO
Peptidylprolyl isomerase
Search

FKBP3

0.57	Peptidyl-prolyl cis-trans isomerase FKBP3

0.72	GO:0061077	chaperone-mediated protein folding
0.72	GO:0000413	protein peptidyl-prolyl isomerization

0.78	GO:0005528	FK506 binding
0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.53	GO:0005515	protein binding
0.48	GO:0004872	receptor activity
0.45	GO:0003723	RNA binding

0.61	GO:0005634	nucleus
0.46	GO:0005737	cytoplasm

0.72

EC:5.2.1.8

GO:0003755

tr|T1ELW8|T1ELW8_HELRO
Uncharacterized protein
Search

0.31	Streptomycin biosynthesis protein StrI

0.53

GO:0055114

oxidation-reduction process

0.54

GO:0016491

oxidoreductase activity

0.30

GO:0044425

membrane part

0.54

GO:0016491

tr|T1ELW9|T1ELW9_HELRO
Serine/threonine-protein phosphatase
Search

PPP1CB

0.49	Serine/threonine-protein phosphatase

0.72	GO:0006470	protein dephosphorylation
0.50	GO:0042752	regulation of circadian rhythm
0.48	GO:0030155	regulation of cell adhesion
0.45	GO:0032922	circadian regulation of gene expression
0.45	GO:0009648	photoperiodism
0.44	GO:0060028	convergent extension involved in axis elongation
0.41	GO:0005977	glycogen metabolic process
0.41	GO:0001889	liver development
0.40	GO:0009605	response to external stimulus
0.39	GO:0051301	cell division

0.77	GO:0004722	protein serine/threonine phosphatase activity
0.57	GO:0050115	myosin-light-chain-phosphatase activity
0.54	GO:0046872	metal ion binding
0.48	GO:0019901	protein kinase binding
0.40	GO:0046982	protein heterodimerization activity

0.84	GO:0000164	protein phosphatase type 1 complex
0.83	GO:0072357	PTW/PP1 phosphatase complex
0.49	GO:0000784	nuclear chromosome, telomeric region
0.44	GO:0005829	cytosol
0.39	GO:0005886	plasma membrane
0.39	GO:0005730	nucleolus
0.38	GO:0005654	nucleoplasm
0.37	GO:0042587	glycogen granule
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome

0.57

EC:3.1.3.53

GO:0050115

tr|T1ELX0|T1ELX0_HELRO
UMP-CMP kinase
Search

CMPK1

0.77	UMP-CMP kinase

0.73	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process
0.69	GO:0006221	pyrimidine nucleotide biosynthetic process
0.69	GO:0046939	nucleotide phosphorylation
0.43	GO:0009132	nucleoside diphosphate metabolic process
0.39	GO:0006352	DNA-templated transcription, initiation
0.39	GO:0009142	nucleoside triphosphate biosynthetic process
0.37	GO:0046940	nucleoside monophosphate phosphorylation
0.35	GO:0018963	phthalate metabolic process
0.35	GO:0000956	nuclear-transcribed mRNA catabolic process
0.34	GO:0022602	ovulation cycle process

0.79	GO:0004127	cytidylate kinase activity
0.78	GO:0009041	uridylate kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0004550	nucleoside diphosphate kinase activity
0.40	GO:0046982	protein heterodimerization activity
0.37	GO:0050145	nucleoside phosphate kinase activity
0.35	GO:0004683	calmodulin-dependent protein kinase activity
0.35	GO:0005516	calmodulin binding

0.58	GO:0005634	nucleus
0.47	GO:0005737	cytoplasm
0.39	GO:0031974	membrane-enclosed lumen
0.37	GO:0043232	intracellular non-membrane-bounded organelle
0.37	GO:0044446	intracellular organelle part
0.34	GO:0019013	viral nucleocapsid
0.34	GO:0070062	extracellular exosome
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016020	membrane

0.79

EC:2.7.4.14

GO:0004127

tr|T1ELX1|T1ELX1_HELRO
Uncharacterized protein
Search

NEK7

0.91	Putative nima never in mitosis-related g2-specific serine/threonine protein kinase

0.64	GO:1904355	positive regulation of telomere capping
0.63	GO:0051973	positive regulation of telomerase activity
0.63	GO:0006468	protein phosphorylation
0.63	GO:0032212	positive regulation of telomere maintenance via telomerase
0.43	GO:0018209	peptidyl-serine modification
0.43	GO:0030071	regulation of mitotic metaphase/anaphase transition
0.41	GO:0007059	chromosome segregation
0.36	GO:0031098	stress-activated protein kinase signaling cascade
0.36	GO:0032147	activation of protein kinase activity
0.35	GO:0042981	regulation of apoptotic process

0.70	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0001222	transcription corepressor binding
0.45	GO:0019894	kinesin binding
0.44	GO:0033613	activating transcription factor binding
0.43	GO:0031625	ubiquitin protein ligase binding
0.43	GO:0019901	protein kinase binding
0.39	GO:0000287	magnesium ion binding

0.55	GO:0005654	nucleoplasm
0.43	GO:0005813	centrosome
0.40	GO:0005829	cytosol
0.38	GO:0043234	protein complex

0.70

GO:0004674

tr|T1ELX2|T1ELX2_HELRO
Uncharacterized protein
Search

RPL18

0.69	Eukaryotic ribosomal protein L18

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.32	GO:0036211	protein modification process
0.32	GO:0016310	phosphorylation

0.64	GO:0003735	structural constituent of ribosome
0.39	GO:0003723	RNA binding
0.34	GO:0001871	pattern binding
0.33	GO:0030246	carbohydrate binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005840	ribosome
0.44	GO:0044445	cytosolic part
0.39	GO:0044446	intracellular organelle part
0.39	GO:0005844	polysome
0.35	GO:0005783	endoplasmic reticulum
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

tr|T1ELX3|T1ELX3_HELRO
Uncharacterized protein
Search

PSMD13

0.90	26S proteasome non-ATPase regulatory subunit 13

0.50	GO:0007127	meiosis I
0.49	GO:0043248	proteasome assembly
0.46	GO:0006511	ubiquitin-dependent protein catabolic process
0.44	GO:0030097	hemopoiesis
0.36	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.35	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation

0.42	GO:0005198	structural molecule activity
0.33	GO:0004175	endopeptidase activity
0.32	GO:0016740	transferase activity

0.68	GO:1905369	endopeptidase complex
0.56	GO:0043234	protein complex
0.44	GO:0005829	cytosol
0.42	GO:0005634	nucleus
0.36	GO:0070062	extracellular exosome
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen
0.30	GO:0016020	membrane

0.32

GO:0016740

tr|T1ELX4|T1ELX4_HELRO
40S ribosomal protein S27
Search

0.71	40S ribosomal protein S27

0.60	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.47	GO:0000028	ribosomal small subunit assembly
0.44	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
0.44	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
0.43	GO:0031571	mitotic G1 DNA damage checkpoint
0.43	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.41	GO:0045727	positive regulation of translation

0.64	GO:0003735	structural constituent of ribosome
0.54	GO:0046872	metal ion binding
0.44	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process
0.44	GO:0008494	translation activator activity
0.34	GO:0003723	RNA binding
0.34	GO:0005515	protein binding
0.32	GO:0003677	DNA binding
0.32	GO:0016787	hydrolase activity

0.61	GO:0005840	ribosome
0.46	GO:0044445	cytosolic part
0.41	GO:0005634	nucleus
0.40	GO:0044446	intracellular organelle part
0.33	GO:0043233	organelle lumen
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016787

tr|T1ELX5|T1ELX5_HELRO
Uncharacterized protein
Search

0.77	GO:0034765	regulation of ion transmembrane transport
0.77	GO:0070588	calcium ion transmembrane transport
0.36	GO:0086010	membrane depolarization during action potential

0.82	GO:0005245	voltage-gated calcium channel activity
0.65	GO:0005509	calcium ion binding

0.81

GO:0005891

voltage-gated calcium channel complex

tr|T1ELX6|T1ELX6_HELRO
Uncharacterized protein
Search

0.35	ATP-dependent RNA helicase

0.54	GO:0006413	translational initiation
0.40	GO:0010501	RNA secondary structure unwinding
0.36	GO:0008380	RNA splicing
0.35	GO:0060255	regulation of macromolecule metabolic process
0.34	GO:0006364	rRNA processing
0.33	GO:0002181	cytoplasmic translation
0.33	GO:0042274	ribosomal small subunit biogenesis
0.33	GO:0000302	response to reactive oxygen species
0.33	GO:0032259	methylation

0.63	GO:0004386	helicase activity
0.55	GO:0003743	translation initiation factor activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0008186	RNA-dependent ATPase activity
0.44	GO:0140098	catalytic activity, acting on RNA
0.33	GO:0008168	methyltransferase activity

0.39	GO:0005730	nucleolus
0.37	GO:0071013	catalytic step 2 spliceosome
0.35	GO:0097078	FAL1-SGD1 complex
0.34	GO:0030688	preribosome, small subunit precursor
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0008168

tr|T1ELX7|T1ELX7_HELRO
Uncharacterized protein
Search

EMC6

0.66	ER membrane protein complex subunit 6

0.54	GO:0000045	autophagosome assembly
0.48	GO:0034975	protein folding in endoplasmic reticulum

0.33

GO:0005515

protein binding

0.83	GO:0072546	ER membrane protein complex
0.57	GO:0097630	intrinsic component of omegasome membrane
0.49	GO:0031301	integral component of organelle membrane
0.33	GO:0005794	Golgi apparatus

tr|T1ELX8|T1ELX8_HELRO
Uncharacterized protein
Search

0.36	Protoporphyrinogen oxidase

0.43	GO:0007275	multicellular organism development
0.43	GO:0009653	anatomical structure morphogenesis
0.42	GO:0070208	protein heterotrimerization
0.42	GO:0030198	extracellular matrix organization
0.42	GO:0010466	negative regulation of peptidase activity
0.41	GO:0052548	regulation of endopeptidase activity
0.41	GO:0007266	Rho protein signal transduction
0.41	GO:0071230	cellular response to amino acid stimulus
0.41	GO:0007179	transforming growth factor beta receptor signaling pathway
0.41	GO:0008217	regulation of blood pressure

0.76	GO:0005201	extracellular matrix structural constituent
0.42	GO:0048407	platelet-derived growth factor binding
0.42	GO:0042802	identical protein binding
0.42	GO:0004867	serine-type endopeptidase inhibitor activity
0.41	GO:0046332	SMAD binding
0.41	GO:0002020	protease binding
0.40	GO:0030674	protein binding, bridging
0.39	GO:0005509	calcium ion binding
0.36	GO:0004175	endopeptidase activity
0.36	GO:0008061	chitin binding

0.65	GO:0005581	collagen trimer
0.57	GO:0044420	extracellular matrix component
0.54	GO:0005578	proteinaceous extracellular matrix
0.41	GO:0099081	supramolecular polymer
0.39	GO:0005615	extracellular space
0.38	GO:0005783	endoplasmic reticulum
0.33	GO:0019012	virion
0.30	GO:0016020	membrane

tr|T1ELX9|T1ELX9_HELRO
Uncharacterized protein
Search

0.70	AP-2 complex subunit alpha

0.71	GO:0072583	clathrin-dependent endocytosis
0.69	GO:0006886	intracellular protein transport
0.43	GO:1900126	negative regulation of hyaluronan biosynthetic process
0.39	GO:0048856	anatomical structure development
0.39	GO:0032501	multicellular organismal process
0.38	GO:0030154	cell differentiation
0.37	GO:0048488	synaptic vesicle endocytosis
0.37	GO:0045807	positive regulation of endocytosis
0.36	GO:0002376	immune system process
0.36	GO:0048259	regulation of receptor-mediated endocytosis

0.84	GO:0035615	clathrin adaptor activity
0.68	GO:0008565	protein transporter activity
0.42	GO:0050750	low-density lipoprotein particle receptor binding
0.40	GO:0019901	protein kinase binding
0.39	GO:0008022	protein C-terminus binding
0.39	GO:0032794	GTPase activating protein binding
0.35	GO:0032403	protein complex binding
0.34	GO:0020037	heme binding
0.34	GO:0009055	electron transfer activity
0.33	GO:0046872	metal ion binding

0.78	GO:0030131	clathrin adaptor complex
0.77	GO:0005905	clathrin-coated pit
0.42	GO:0032433	filopodium tip
0.40	GO:0045334	clathrin-coated endocytic vesicle
0.39	GO:0005794	Golgi apparatus
0.39	GO:0036062	presynaptic periactive zone
0.36	GO:0030666	endocytic vesicle membrane
0.36	GO:0016323	basolateral plasma membrane
0.35	GO:0030125	clathrin vesicle coat
0.35	GO:0016324	apical plasma membrane

tr|T1ELY0|T1ELY0_HELRO
Uncharacterized protein
Search

RSL24D1

0.66	Ribosomal L24 domain-containing protein 1

0.60	GO:1902626	assembly of large subunit precursor of preribosome
0.55	GO:0042273	ribosomal large subunit biogenesis
0.54	GO:0043043	peptide biosynthetic process
0.52	GO:0042255	ribosome assembly
0.51	GO:0044267	cellular protein metabolic process
0.49	GO:0010467	gene expression
0.48	GO:0009059	macromolecule biosynthetic process
0.41	GO:0032781	positive regulation of ATPase activity

0.57	GO:0003735	structural constituent of ribosome
0.44	GO:0003723	RNA binding
0.41	GO:0001671	ATPase activator activity
0.34	GO:0005515	protein binding

0.60	GO:0030529	intracellular ribonucleoprotein complex
0.59	GO:0043232	intracellular non-membrane-bounded organelle
0.54	GO:0031981	nuclear lumen
0.54	GO:0044444	cytoplasmic part
0.30	GO:0031224	intrinsic component of membrane

tr|T1ELY1|T1ELY1_HELRO
Uncharacterized protein
Search

0.49	Polypeptide N-acetylgalactosaminyltransferase

0.69	GO:0006486	protein glycosylation
0.45	GO:0007286	spermatid development
0.38	GO:0018210	peptidyl-threonine modification
0.32	GO:0005975	carbohydrate metabolic process

0.64	GO:0030246	carbohydrate binding
0.61	GO:0016757	transferase activity, transferring glycosyl groups
0.35	GO:0140096	catalytic activity, acting on a protein
0.34	GO:0043169	cation binding

0.67	GO:0000139	Golgi membrane
0.41	GO:0031410	cytoplasmic vesicle
0.35	GO:0098805	whole membrane
0.30	GO:0031224	intrinsic component of membrane

0.61

GO:0016757

tr|T1ELY2|T1ELY2_HELRO
Uncharacterized protein
Search

DNAJC13

0.91	DnaJ like protein subfamily C member 13

0.86	GO:1902954	regulation of early endosome to recycling endosome transport
0.85	GO:2000641	regulation of early endosome to late endosome transport
0.81	GO:0007032	endosome organization
0.66	GO:0045022	early endosome to late endosome transport
0.57	GO:0006898	receptor-mediated endocytosis
0.44	GO:0001649	osteoblast differentiation
0.41	GO:0043312	neutrophil degranulation
0.37	GO:0015031	protein transport

0.36

GO:0005515

protein binding

0.81	GO:0031901	early endosome membrane
0.79	GO:0071203	WASH complex
0.68	GO:0005829	cytosol
0.54	GO:0043231	intracellular membrane-bounded organelle
0.43	GO:0070062	extracellular exosome
0.40	GO:0030667	secretory granule membrane
0.35	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1ELY3|T1ELY3_HELRO
Histone acetyltransferase
Search

KAT5

0.55	Histone acetyltransferase

0.78	GO:0016573	histone acetylation
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.49	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
0.48	GO:0032703	negative regulation of interleukin-2 production
0.48	GO:0071392	cellular response to estradiol stimulus
0.47	GO:1901985	positive regulation of protein acetylation
0.46	GO:0010212	response to ionizing radiation
0.44	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process

0.80	GO:0004402	histone acetyltransferase activity
0.47	GO:0070491	repressing transcription factor binding
0.45	GO:0003713	transcription coactivator activity
0.35	GO:0050681	androgen receptor binding
0.34	GO:0016428	tRNA (cytosine-5-)-methyltransferase activity
0.33	GO:0046872	metal ion binding
0.33	GO:0003676	nucleic acid binding

0.79	GO:0035267	NuA4 histone acetyltransferase complex
0.47	GO:0000812	Swr1 complex
0.44	GO:0005667	transcription factor complex
0.44	GO:0005730	nucleolus
0.39	GO:0005705	polytene chromosome interband
0.37	GO:0048471	perinuclear region of cytoplasm
0.30	GO:0016020	membrane

0.80

GO:0004402

tr|T1ELY4|T1ELY4_HELRO
Uncharacterized protein
Search

JPH3

0.67	Junctophilin-2

0.57	GO:0050885	neuromuscular process controlling balance
0.56	GO:0007612	learning
0.56	GO:0048167	regulation of synaptic plasticity
0.55	GO:0051924	regulation of calcium ion transport
0.52	GO:0035640	exploration behavior
0.51	GO:0050848	regulation of calcium-mediated signaling
0.51	GO:2001257	regulation of cation channel activity
0.51	GO:0060402	calcium ion transport into cytosol
0.51	GO:0051283	negative regulation of sequestering of calcium ion
0.51	GO:0007613	memory

0.51	GO:0015278	calcium-release channel activity
0.32	GO:0004252	serine-type endopeptidase activity

0.80	GO:0030314	junctional membrane complex
0.49	GO:0005783	endoplasmic reticulum
0.47	GO:0043198	dendritic shaft
0.47	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.45	GO:0031984	organelle subcompartment
0.40	GO:0005886	plasma membrane
0.34	GO:0098588	bounding membrane of organelle
0.34	GO:0030117	membrane coat
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0004252

tr|T1ELY5|T1ELY5_HELRO
Uncharacterized protein
Search

0.10	cAMP-dependent protein kinase catalytic subunit alpha

0.63	GO:0006468	protein phosphorylation
0.54	GO:0007165	signal transduction
0.43	GO:0007163	establishment or maintenance of cell polarity
0.42	GO:0018209	peptidyl-serine modification
0.40	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.40	GO:0006754	ATP biosynthetic process
0.38	GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
0.38	GO:0016477	cell migration
0.38	GO:0006915	apoptotic process
0.38	GO:0050670	regulation of lymphocyte proliferation

0.68	GO:0004674	protein serine/threonine kinase activity
0.56	GO:0017049	GTP-Rho binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.43	GO:0046872	metal ion binding
0.38	GO:0015078	hydrogen ion transmembrane transporter activity
0.38	GO:0050681	androgen receptor binding
0.37	GO:0035173	histone kinase activity

0.41	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
0.37	GO:0097610	cell surface furrow
0.37	GO:0030496	midbody
0.37	GO:0032155	cell division site part
0.37	GO:0016324	apical plasma membrane
0.37	GO:0005634	nucleus
0.37	GO:0030864	cortical actin cytoskeleton
0.36	GO:0005768	endosome
0.36	GO:0016235	aggresome
0.36	GO:0048471	perinuclear region of cytoplasm

0.68

GO:0004674

tr|T1ELY6|T1ELY6_HELRO
Uncharacterized protein
Search

LSM6

0.79	Small nuclear ribonucleoprotein f

0.75	GO:0000398	mRNA splicing, via spliceosome
0.46	GO:0030490	maturation of SSU-rRNA
0.35	GO:0007034	vacuolar transport
0.35	GO:0006402	mRNA catabolic process
0.34	GO:0008033	tRNA processing
0.32	GO:0055085	transmembrane transport

0.58	GO:0003723	RNA binding
0.34	GO:0005515	protein binding
0.32	GO:0005215	transporter activity

0.79	GO:0005732	small nucleolar ribonucleoprotein complex
0.73	GO:0005681	spliceosomal complex
0.48	GO:0005688	U6 snRNP
0.47	GO:0000932	P-body
0.47	GO:0046540	U4/U6 x U5 tri-snRNP complex
0.45	GO:0005730	nucleolus
0.43	GO:0019013	viral nucleocapsid
0.36	GO:0070062	extracellular exosome
0.33	GO:0005654	nucleoplasm
0.33	GO:0005829	cytosol

tr|T1ELY7|T1ELY7_HELRO
Uncharacterized protein
Search

PSMC2

0.80	26S proteasome regulatory subunit 7

0.78	GO:1901800	positive regulation of proteasomal protein catabolic process
0.68	GO:0030163	protein catabolic process
0.55	GO:0006508	proteolysis
0.51	GO:0043632	modification-dependent macromolecule catabolic process
0.47	GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly
0.45	GO:0034976	response to endoplasmic reticulum stress
0.45	GO:0010243	response to organonitrogen compound
0.43	GO:0044267	cellular protein metabolic process
0.37	GO:0001649	osteoblast differentiation
0.36	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition

0.79	GO:0036402	proteasome-activating ATPase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0008233	peptidase activity
0.46	GO:0017025	TBP-class protein binding
0.32	GO:0046872	metal ion binding

0.57	GO:1905369	endopeptidase complex
0.53	GO:0036464	cytoplasmic ribonucleoprotein granule
0.49	GO:0043234	protein complex
0.49	GO:0005829	cytosol
0.42	GO:0031981	nuclear lumen
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen
0.35	GO:0043197	dendritic spine
0.33	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.51

GO:0008233

tr|T1ELY8|T1ELY8_HELRO
Uncharacterized protein
Search

0.68	AMP deaminase

0.80

GO:0032264

IMP salvage

0.85	GO:0003876	AMP deaminase activity
0.51	GO:0046872	metal ion binding

0.38	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.85

EC:3.5.4.6

GO:0003876

tr|T1ELY9|T1ELY9_HELRO
Uncharacterized protein
Search

CDC42

0.77	Cell division control protein 42 homolog (inferred by orthology to a C. elegans protein)

0.77	GO:0007264	small GTPase mediated signal transduction
0.58	GO:0120032	regulation of plasma membrane bounded cell projection assembly
0.57	GO:0030010	establishment of cell polarity
0.57	GO:0030307	positive regulation of cell growth
0.56	GO:0007119	budding cell isotropic bud growth
0.55	GO:1905708	regulation of cell morphogenesis involved in conjugation with cellular fusion
0.55	GO:0060178	regulation of exocyst localization
0.55	GO:0007088	regulation of mitotic nuclear division
0.54	GO:0070786	positive regulation of growth of unicellular organism as a thread of attached cells
0.54	GO:2000220	regulation of pseudohyphal growth

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.49	GO:0051022	Rho GDP-dissociation inhibitor binding
0.49	GO:0032427	GBD domain binding
0.48	GO:0034191	apolipoprotein A-I receptor binding
0.48	GO:0031996	thioesterase binding
0.48	GO:0030742	GTP-dependent protein binding
0.45	GO:0019901	protein kinase binding
0.44	GO:0061630	ubiquitin protein ligase activity
0.43	GO:0042802	identical protein binding

0.55	GO:0000322	storage vacuole
0.53	GO:0120038	plasma membrane bounded cell projection part
0.53	GO:0000131	incipient cellular bud site
0.52	GO:0005934	cellular bud tip
0.52	GO:0005940	septin ring
0.52	GO:0005937	mating projection
0.52	GO:0005935	cellular bud neck
0.51	GO:0031965	nuclear membrane
0.50	GO:0098852	lytic vacuole membrane
0.46	GO:0031256	leading edge membrane

0.33

GO:0016773

tr|T1ELZ0|T1ELZ0_HELRO
Calcium-transporting ATPase
Search

0.58	Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type

0.77	GO:0070588	calcium ion transmembrane transport
0.69	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.38	GO:0044057	regulation of system process
0.38	GO:0001947	heart looping
0.34	GO:0051241	negative regulation of multicellular organismal process
0.34	GO:0051240	positive regulation of multicellular organismal process

0.80	GO:0005388	calcium-transporting ATPase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005509	calcium ion binding

0.36	GO:0033017	sarcoplasmic reticulum membrane
0.35	GO:0031673	H zone
0.34	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.34	GO:0031674	I band
0.34	GO:0048471	perinuclear region of cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.80

EC:3.6.3.8

GO:0005388

tr|T1ELZ1|T1ELZ1_HELRO
Uncharacterized protein
Search

EMC8

0.94	ER membrane protein complex subunit 8

0.37

GO:0005515

protein binding

0.81	GO:0072546	ER membrane protein complex
0.62	GO:0005829	cytosol
0.55	GO:0005739	mitochondrion
0.35	GO:0005634	nucleus

tr|T1ELZ2|T1ELZ2_HELRO
Uncharacterized protein
Search

HARS

0.64	Histidyl-tRNA synthetase

0.77	GO:0006427	histidyl-tRNA aminoacylation
0.46	GO:0032543	mitochondrial translation

0.77	GO:0004821	histidine-tRNA ligase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0042802	identical protein binding
0.32	GO:0003723	RNA binding

0.49	GO:0005737	cytoplasm
0.38	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016020	membrane

0.77

EC:6.1.1.21

GO:0004821

tr|T1ELZ3|T1ELZ3_HELRO
Carbonic anhydrase
Search

0.46	Carbonic anhydrase

0.41	GO:0006730	one-carbon metabolic process
0.37	GO:0043461	proton-transporting ATP synthase complex assembly
0.32	GO:0055085	transmembrane transport
0.32	GO:0022900	electron transport chain

0.78	GO:0004089	carbonate dehydratase activity
0.63	GO:0008270	zinc ion binding
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.32	GO:0009055	electron transfer activity

0.38	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.78

EC:4.2.1.1

GO:0004089

tr|T1ELZ4|T1ELZ4_HELRO
Uncharacterized protein
Search

0.74	Striatin, calmodulin binding protein 3

0.54	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.44	GO:0016192	vesicle-mediated transport

0.56	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.43	GO:0003676	nucleic acid binding

0.30

GO:0031224

intrinsic component of membrane

0.56

EC:3.1.26.4

GO:0004523

tr|T1ELZ5|T1ELZ5_HELRO
Uncharacterized protein
Search

DDO

0.40	FAD dependent oxidoreductase

0.76	GO:0046416	D-amino acid metabolic process
0.53	GO:0055114	oxidation-reduction process
0.49	GO:0007625	grooming behavior
0.49	GO:0007320	insemination
0.47	GO:0006531	aspartate metabolic process
0.45	GO:0042445	hormone metabolic process
0.43	GO:1901606	alpha-amino acid catabolic process
0.35	GO:0043649	dicarboxylic acid catabolic process
0.33	GO:0055085	transmembrane transport
0.32	GO:0034641	cellular nitrogen compound metabolic process

0.83	GO:0003884	D-amino-acid oxidase activity
0.73	GO:0071949	FAD binding
0.50	GO:0015922	aspartate oxidase activity
0.44	GO:0005102	receptor binding
0.33	GO:0022857	transmembrane transporter activity

0.43	GO:0005829	cytosol
0.35	GO:0031907	microbody lumen
0.35	GO:0044439	peroxisomal part
0.30	GO:0016020	membrane

0.83

EC:1.4.3.3

GO:0003884

tr|T1ELZ6|T1ELZ6_HELRO
Glutathione peroxidase
Search

GPX7

0.48	Glutathione peroxidase

0.70	GO:0006979	response to oxidative stress
0.68	GO:0098869	cellular oxidant detoxification
0.52	GO:0055114	oxidation-reduction process
0.34	GO:0048193	Golgi vesicle transport

0.79	GO:0004602	glutathione peroxidase activity
0.49	GO:0051920	peroxiredoxin activity
0.38	GO:0004096	catalase activity
0.33	GO:0046983	protein dimerization activity

0.37	GO:0005783	endoplasmic reticulum
0.34	GO:0030008	TRAPP complex
0.34	GO:0009536	plastid
0.30	GO:0031224	intrinsic component of membrane

0.79

EC:1.11.1.9

GO:0004602

tr|T1ELZ7|T1ELZ7_HELRO
Uncharacterized protein
Search

0.75	T-box transcription factor TBX1-A

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.49	GO:0060017	parathyroid gland development
0.48	GO:0060023	soft palate development
0.48	GO:0060037	pharyngeal system development
0.48	GO:0048538	thymus development
0.47	GO:0048703	embryonic viscerocranium morphogenesis
0.45	GO:0007507	heart development

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.44	GO:0042803	protein homodimerization activity
0.35	GO:0001067	regulatory region nucleic acid binding
0.33	GO:0005525	GTP binding

0.61	GO:0005634	nucleus
0.34	GO:0008021	synaptic vesicle
0.30	GO:0016020	membrane

tr|T1ELZ8|T1ELZ8_HELRO
Uncharacterized protein
Search

PCK2

0.51	Phosphoenolpyruvate carboxykinase

0.73	GO:0019319	hexose biosynthetic process
0.71	GO:0006006	glucose metabolic process
0.52	GO:0016310	phosphorylation
0.42	GO:0046327	glycerol biosynthetic process from pyruvate
0.42	GO:0061402	positive regulation of transcription from RNA polymerase II promoter in response to acidic pH
0.42	GO:0051365	cellular response to potassium ion starvation
0.41	GO:1901700	response to oxygen-containing compound
0.41	GO:0010033	response to organic substance
0.40	GO:0009719	response to endogenous stimulus
0.39	GO:1901698	response to nitrogen compound

0.82	GO:0004613	phosphoenolpyruvate carboxykinase (GTP) activity
0.66	GO:0005525	GTP binding
0.54	GO:0016301	kinase activity
0.41	GO:0030145	manganese ion binding
0.38	GO:0043177	organic acid binding
0.37	GO:0000287	magnesium ion binding
0.35	GO:0019157	malate oxidase activity
0.35	GO:0050692	DBD domain binding
0.35	GO:0051379	epinephrine binding
0.34	GO:0047134	protein-disulfide reductase activity

0.40	GO:0005739	mitochondrion
0.38	GO:0005829	cytosol
0.35	GO:0070062	extracellular exosome
0.33	GO:0043233	organelle lumen
0.32	GO:0044446	intracellular organelle part

0.82	EC:4.1.1.32	GO:0004613
0.35	KEGG:R00360	GO:0019157

tr|T1ELZ9|T1ELZ9_HELRO
Uncharacterized protein
Search

0.70	Guanine nucleotide-binding protein Gk subunit alpha

0.82	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.41	GO:0014045	establishment of endothelial blood-brain barrier
0.41	GO:0042595	behavioral response to starvation
0.41	GO:0060857	establishment of glial blood-brain barrier
0.41	GO:0061343	cell adhesion involved in heart morphogenesis
0.41	GO:0001737	establishment of imaginal disc-derived wing hair orientation
0.41	GO:0019991	septate junction assembly
0.41	GO:0007419	ventral cord development
0.41	GO:0032291	axon ensheathment in central nervous system
0.41	GO:0045886	negative regulation of synaptic growth at neuromuscular junction

0.81	GO:0031683	G-protein beta/gamma-subunit complex binding
0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.64	GO:0004871	signal transducer activity
0.41	GO:0001664	G-protein coupled receptor binding
0.37	GO:0019003	GDP binding
0.35	GO:0046872	metal ion binding
0.35	GO:0051428	peptide hormone receptor binding
0.33	GO:0032794	GTPase activating protein binding
0.33	GO:0019904	protein domain specific binding

0.44	GO:1905360	GTPase complex
0.44	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.40	GO:0098797	plasma membrane protein complex
0.36	GO:0030496	midbody
0.36	GO:0005813	centrosome
0.35	GO:0000139	Golgi membrane
0.35	GO:0005730	nucleolus
0.35	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0042588	zymogen granule
0.33	GO:0005765	lysosomal membrane

tr|T1EM00|T1EM00_HELRO
Uncharacterized protein
Search

0.20	Arylsulfatase

0.45	GO:0030111	regulation of Wnt signaling pathway
0.45	GO:0009888	tissue development
0.45	GO:0014846	esophagus smooth muscle contraction
0.45	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway
0.45	GO:0030201	heparan sulfate proteoglycan metabolic process
0.45	GO:0007399	nervous system development
0.45	GO:0048513	animal organ development
0.44	GO:0030154	cell differentiation
0.44	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway
0.44	GO:0009967	positive regulation of signal transduction

0.75	GO:0008484	sulfuric ester hydrolase activity
0.47	GO:0005509	calcium ion binding
0.38	GO:0017095	heparan sulfate 6-O-sulfotransferase activity
0.33	GO:0016791	phosphatase activity

0.50	GO:0009986	cell surface
0.48	GO:0005794	Golgi apparatus
0.48	GO:0005783	endoplasmic reticulum
0.41	GO:0005615	extracellular space
0.39	GO:0098857	membrane microdomain
0.36	GO:0005886	plasma membrane
0.35	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.75

EC:3.1.6

GO:0008484

tr|T1EM01|T1EM01_HELRO
Uncharacterized protein
Search

NUDCD2

0.97	NudC domain-containing protein 2

0.56	GO:0006457	protein folding
0.55	GO:0032502	developmental process

0.57

GO:0051082

unfolded protein binding

0.45	GO:0000777	condensed chromosome kinetochore
0.45	GO:0000922	spindle pole
0.44	GO:0005815	microtubule organizing center
0.43	GO:0070062	extracellular exosome
0.42	GO:0005737	cytoplasm

tr|T1EM02|T1EM02_HELRO
Uncharacterized protein
Search

0.30

GO:0044425

membrane part

tr|T1EM03|T1EM03_HELRO
Peptidyl-prolyl cis-trans isomerase
Search

0.49	Peptidyl-prolyl cis-trans isomerase

0.71	GO:0000413	protein peptidyl-prolyl isomerization
0.68	GO:0006457	protein folding
0.38	GO:0010759	positive regulation of macrophage chemotaxis
0.37	GO:0050918	positive chemotaxis
0.37	GO:0060326	cell chemotaxis
0.36	GO:0006915	apoptotic process
0.36	GO:0001666	response to hypoxia

0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.38	GO:0042056	chemoattractant activity
0.37	GO:0008009	chemokine activity
0.35	GO:0016018	cyclosporin A binding
0.32	GO:0003723	RNA binding

0.34	GO:0005829	cytosol
0.34	GO:0005739	mitochondrion
0.34	GO:0005929	cilium
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.72

EC:5.2.1.8

GO:0003755

tr|T1EM04|T1EM04_HELRO
Uncharacterized protein
Search

CRIPT

0.94	CXXC repeat containing interactor of PDZ3 domain

0.78	GO:1902897	regulation of postsynaptic density protein 95 clustering
0.75	GO:0035372	protein localization to microtubule
0.70	GO:0031122	cytoplasmic microtubule organization
0.56	GO:0045184	establishment of protein localization
0.36	GO:0032259	methylation

0.82	GO:0030165	PDZ domain binding
0.79	GO:0097110	scaffold protein binding
0.63	GO:0032403	protein complex binding
0.63	GO:0008017	microtubule binding
0.36	GO:0008168	methyltransferase activity
0.34	GO:0046872	metal ion binding
0.34	GO:0003676	nucleic acid binding

0.76	GO:0001650	fibrillar center
0.73	GO:0043198	dendritic shaft
0.71	GO:0043197	dendritic spine
0.70	GO:0014069	postsynaptic density
0.68	GO:0043025	neuronal cell body
0.45	GO:0030054	cell junction
0.39	GO:0005737	cytoplasm

0.36

GO:0008168

tr|T1EM05|T1EM05_HELRO
Uncharacterized protein
Search

0.38	Zinc finger domain containing protein

0.41	GO:0040025	vulval development
0.37	GO:0021684	cerebellar granular layer formation
0.37	GO:0021702	cerebellar Purkinje cell differentiation
0.36	GO:2001141	regulation of RNA biosynthetic process
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:0010468	regulation of gene expression
0.34	GO:0045087	innate immune response
0.33	GO:0006351	transcription, DNA-templated
0.33	GO:0051254	positive regulation of RNA metabolic process
0.33	GO:0010557	positive regulation of macromolecule biosynthetic process

0.51	GO:0003676	nucleic acid binding
0.36	GO:0046872	metal ion binding
0.34	GO:0003700	DNA binding transcription factor activity

0.36

GO:0005634

nucleus

tr|T1EM06|T1EM06_HELRO
Uncharacterized protein
Search

0.74	Guanylyl cyclase-activating protein 2

0.34	GO:0048841	regulation of axon extension involved in axon guidance
0.32	GO:0055114	oxidation-reduction process

0.70	GO:0005509	calcium ion binding
0.34	GO:0016174	NAD(P)H oxidase activity

0.30

GO:0016020

membrane

0.34

EC:1.6.3.1

GO:0016174

tr|T1EM07|T1EM07_HELRO
Uncharacterized protein
Search

0.78	Transcriptional enhancer factor TEF-1

0.84	GO:0035329	hippo signaling
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0006351	transcription, DNA-templated
0.55	GO:0051254	positive regulation of RNA metabolic process
0.55	GO:0010557	positive regulation of macromolecule biosynthetic process
0.54	GO:0031328	positive regulation of cellular biosynthetic process
0.45	GO:0048568	embryonic organ development
0.37	GO:1902459	positive regulation of stem cell population maintenance

0.61	GO:0003700	DNA binding transcription factor activity
0.53	GO:0003677	DNA binding
0.46	GO:0001085	RNA polymerase II transcription factor binding
0.45	GO:0001067	regulatory region nucleic acid binding
0.37	GO:0001223	transcription coactivator binding
0.36	GO:0001134	transcription factor activity, transcription factor recruiting
0.35	GO:0046982	protein heterodimerization activity

0.59	GO:0005634	nucleus
0.44	GO:0005667	transcription factor complex
0.37	GO:0043233	organelle lumen
0.36	GO:0044446	intracellular organelle part

tr|T1EM08|T1EM08_HELRO
Uncharacterized protein
Search

0.63	Voltage-dependent T-type calcium channel subunit alpha-1G

0.75	GO:0070588	calcium ion transmembrane transport
0.59	GO:0034765	regulation of ion transmembrane transport
0.48	GO:0070509	calcium ion import
0.38	GO:0019228	neuronal action potential
0.38	GO:0086010	membrane depolarization during action potential
0.37	GO:0035725	sodium ion transmembrane transport
0.33	GO:0006508	proteolysis

0.79	GO:0005245	voltage-gated calcium channel activity
0.38	GO:0005248	voltage-gated sodium channel activity
0.33	GO:0070001	aspartic-type peptidase activity
0.33	GO:0004175	endopeptidase activity
0.33	GO:0008270	zinc ion binding
0.32	GO:0003676	nucleic acid binding

0.78	GO:0005891	voltage-gated calcium channel complex
0.33	GO:0005887	integral component of plasma membrane

tr|T1EM09|T1EM09_HELRO
Uncharacterized protein
Search

DNAJB1

0.80	DnaJ like protein subfamily B member 1

0.66	GO:0006457	protein folding
0.52	GO:0097201	negative regulation of transcription from RNA polymerase II promoter in response to stress
0.52	GO:0090084	negative regulation of inclusion body assembly
0.51	GO:0032781	positive regulation of ATPase activity
0.42	GO:0009408	response to heat
0.37	GO:0006260	DNA replication
0.36	GO:0002088	lens development in camera-type eye
0.35	GO:0071586	CAAX-box protein processing
0.35	GO:0006986	response to unfolded protein
0.35	GO:1900034	regulation of cellular response to heat

0.69	GO:0051082	unfolded protein binding
0.51	GO:0031072	heat shock protein binding
0.51	GO:0001106	RNA polymerase II transcription corepressor activity
0.51	GO:0001671	ATPase activator activity
0.50	GO:0051117	ATPase binding
0.49	GO:0051087	chaperone binding
0.49	GO:0045296	cadherin binding
0.38	GO:0008270	zinc ion binding
0.37	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding

0.45	GO:0005829	cytosol
0.43	GO:0005634	nucleus
0.38	GO:0031974	membrane-enclosed lumen
0.37	GO:0070062	extracellular exosome
0.36	GO:0044446	intracellular organelle part
0.35	GO:0005886	plasma membrane
0.34	GO:0014069	postsynaptic density
0.34	GO:0043232	intracellular non-membrane-bounded organelle
0.32	GO:0044815	DNA packaging complex
0.32	GO:0032993	protein-DNA complex

0.34

GO:0004222

tr|T1EM10|T1EM10_HELRO
S-formylglutathione hydrolase
Search

ESD

0.59	S-formylglutathione hydrolase

0.81	GO:0046294	formaldehyde catabolic process
0.36	GO:0036159	inner dynein arm assembly
0.36	GO:0003341	cilium movement
0.35	GO:1901685	glutathione derivative metabolic process
0.34	GO:0007276	gamete generation
0.33	GO:0044272	sulfur compound biosynthetic process
0.32	GO:1901566	organonitrogen compound biosynthetic process

0.81	GO:0018738	S-formylglutathione hydrolase activity
0.69	GO:0052689	carboxylic ester hydrolase activity
0.45	GO:0042802	identical protein binding
0.34	GO:0019213	deacetylase activity

0.46	GO:0005737	cytoplasm
0.37	GO:0097708	intracellular vesicle
0.36	GO:0070062	extracellular exosome
0.35	GO:0044441	ciliary part
0.34	GO:0044430	cytoskeletal part
0.33	GO:0012505	endomembrane system
0.33	GO:0043233	organelle lumen
0.32	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

0.81	EC:3.1.2.12	GO:0018738
0.81	KEGG:R00527	GO:0018738

tr|T1EM11|T1EM11_HELRO
Uncharacterized protein
Search

0.85	Myocyte enhancer factor 2ca variant 5

0.74	GO:0045944	positive regulation of transcription by RNA polymerase II
0.58	GO:0006351	transcription, DNA-templated
0.49	GO:0060914	heart formation
0.48	GO:0055007	cardiac muscle cell differentiation
0.47	GO:0003143	embryonic heart tube morphogenesis
0.47	GO:0003185	sinoatrial valve morphogenesis
0.46	GO:2000987	positive regulation of behavioral fear response
0.46	GO:2000111	positive regulation of macrophage apoptotic process
0.46	GO:0010694	positive regulation of alkaline phosphatase activity
0.46	GO:0007521	muscle cell fate determination

0.77	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.68	GO:0046983	protein dimerization activity
0.44	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding
0.44	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding
0.44	GO:0071837	HMG box domain binding
0.43	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.43	GO:0003680	AT DNA binding
0.43	GO:0001158	enhancer sequence-specific DNA binding
0.43	GO:0033613	activating transcription factor binding
0.42	GO:0042826	histone deacetylase binding

0.61	GO:0005634	nucleus
0.41	GO:0098794	postsynapse
0.41	GO:0070013	intracellular organelle lumen
0.38	GO:0044446	intracellular organelle part
0.38	GO:0016528	sarcoplasm
0.38	GO:0043234	protein complex
0.34	GO:0030017	sarcomere
0.30	GO:0016020	membrane

0.33

GO:0004222

tr|T1EM12|T1EM12_HELRO
Uncharacterized protein
Search

FOXB1

0.80	Forkhead B

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0061381	cell migration in diencephalon
0.55	GO:0061374	mammillothalamic axonal tract development
0.54	GO:0061379	inferior colliculus development
0.53	GO:0021855	hypothalamus cell migration
0.53	GO:0007412	axon target recognition
0.53	GO:0033504	floor plate development
0.51	GO:0008542	visual learning

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|T1EM13|T1EM13_HELRO
Uncharacterized protein
Search

LSM3

0.88	LSM3 homolog, U6 small nuclear RNA and mRNA degradation-associated

0.78	GO:0000956	nuclear-transcribed mRNA catabolic process
0.75	GO:0000398	mRNA splicing, via spliceosome
0.51	GO:0033962	cytoplasmic mRNA processing body assembly

0.40	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.57	GO:0030529	intracellular ribonucleoprotein complex
0.50	GO:1990726	Lsm1-7-Pat1 complex
0.46	GO:0044428	nuclear part
0.44	GO:1902494	catalytic complex
0.40	GO:0043232	intracellular non-membrane-bounded organelle
0.40	GO:0019013	viral nucleocapsid
0.39	GO:0044444	cytoplasmic part
0.33	GO:0031974	membrane-enclosed lumen

tr|T1EM14|T1EM14_HELRO
Uncharacterized protein
Search

HMBS

0.44	Hydroxymethylbilane synthase a

0.79	GO:0018160	peptidyl-pyrromethane cofactor linkage
0.69	GO:0033014	tetrapyrrole biosynthetic process
0.42	GO:0042168	heme metabolic process
0.42	GO:0046148	pigment biosynthetic process
0.40	GO:0051188	cofactor biosynthetic process
0.37	GO:0046501	protoporphyrinogen IX metabolic process
0.35	GO:0006886	intracellular protein transport
0.35	GO:0016192	vesicle-mediated transport
0.35	GO:0071418	cellular response to amine stimulus
0.35	GO:0071284	cellular response to lead ion

0.80	GO:0004418	hydroxymethylbilane synthase activity
0.34	GO:0043176	amine binding
0.34	GO:0004852	uroporphyrinogen-III synthase activity
0.33	GO:0031406	carboxylic acid binding
0.33	GO:0005515	protein binding
0.33	GO:0004672	protein kinase activity
0.33	GO:0050662	coenzyme binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding

0.36	GO:0005737	cytoplasm
0.34	GO:0030424	axon
0.34	GO:0000793	condensed chromosome
0.33	GO:0005634	nucleus

0.80	EC:2.5.1.61	GO:0004418
0.80	KEGG:R00084	GO:0004418

tr|T1EM15|T1EM15_HELRO
Pyruvate kinase
Search

0.47	Pyruvate kinase PKM

0.70	GO:0006757	ATP generation from ADP
0.68	GO:0006090	pyruvate metabolic process
0.67	GO:0016052	carbohydrate catabolic process
0.67	GO:0019362	pyridine nucleotide metabolic process
0.35	GO:0012501	programmed cell death
0.34	GO:0006006	glucose metabolic process
0.33	GO:0072330	monocarboxylic acid biosynthetic process
0.33	GO:0044282	small molecule catabolic process
0.32	GO:0055114	oxidation-reduction process

0.78	GO:0004743	pyruvate kinase activity
0.77	GO:0030955	potassium ion binding
0.64	GO:0000287	magnesium ion binding
0.60	GO:0016301	kinase activity
0.35	GO:0045296	cadherin binding

0.35	GO:0043209	myelin sheath
0.35	GO:0005929	cilium
0.34	GO:0005829	cytosol
0.33	GO:0005634	nucleus
0.33	GO:0005739	mitochondrion

0.78

EC:2.7.1.40

GO:0004743

tr|T1EM16|T1EM16_HELRO
Uncharacterized protein
Search

RPS15A

0.63	Small subunit ribosomal protein S15Ae

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.45	GO:0045787	positive regulation of cell cycle
0.45	GO:0008284	positive regulation of cell proliferation
0.44	GO:0009615	response to virus
0.36	GO:0006613	cotranslational protein targeting to membrane
0.36	GO:0008340	determination of adult lifespan
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

0.64	GO:0003735	structural constituent of ribosome
0.33	GO:0003723	RNA binding
0.33	GO:0005515	protein binding
0.32	GO:0016787	hydrolase activity

0.61	GO:0005840	ribosome
0.45	GO:0044445	cytosolic part
0.41	GO:0044446	intracellular organelle part
0.40	GO:0005739	mitochondrion
0.36	GO:0031012	extracellular matrix
0.36	GO:0005791	rough endoplasmic reticulum
0.36	GO:0070062	extracellular exosome
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0098588	bounding membrane of organelle
0.34	GO:0098796	membrane protein complex

0.32

GO:0016787

tr|T1EM17|T1EM17_HELRO
Uncharacterized protein
Search

0.57	GO:0006869	lipid transport
0.56	GO:0007601	visual perception
0.55	GO:0055085	transmembrane transport
0.53	GO:0045494	photoreceptor cell maintenance
0.50	GO:0097035	regulation of membrane lipid distribution
0.49	GO:0015748	organophosphate ester transport
0.45	GO:0015711	organic anion transport
0.38	GO:0048730	epidermis morphogenesis
0.38	GO:0031032	actomyosin structure organization
0.35	GO:0007603	phototransduction, visible light

0.66	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.56	GO:0090555	phosphatidylethanolamine-translocating ATPase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0005516	calmodulin binding
0.36	GO:0003779	actin binding
0.34	GO:0005234	extracellularly glutamate-gated ion channel activity
0.34	GO:0004970	ionotropic glutamate receptor activity

0.53	GO:0001750	photoreceptor outer segment
0.49	GO:0005887	integral component of plasma membrane
0.40	GO:0043227	membrane-bounded organelle
0.38	GO:0043229	intracellular organelle
0.37	GO:0031253	cell projection membrane
0.34	GO:0098805	whole membrane
0.34	GO:0098794	postsynapse
0.34	GO:0012505	endomembrane system
0.33	GO:0044444	cytoplasmic part

tr|T1EM18|T1EM18_HELRO
Uncharacterized protein
Search

RNASEH1

0.41	Ribonuclease H

0.70	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.45	GO:0043137	DNA replication, removal of RNA primer
0.35	GO:0005975	carbohydrate metabolic process
0.35	GO:0006264	mitochondrial DNA replication
0.34	GO:0019509	L-methionine salvage from methylthioadenosine
0.33	GO:0016075	rRNA catabolic process
0.32	GO:0006396	RNA processing
0.32	GO:0055114	oxidation-reduction process

0.74	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.61	GO:0000287	magnesium ion binding
0.51	GO:0003676	nucleic acid binding
0.37	GO:0016868	intramolecular transferase activity, phosphotransferases
0.34	GO:0010309	acireductone dioxygenase [iron(II)-requiring] activity
0.34	GO:0042803	protein homodimerization activity
0.33	GO:0032296	double-stranded RNA-specific ribonuclease activity
0.33	GO:0005506	iron ion binding

0.40	GO:0005634	nucleus
0.36	GO:0000785	chromatin
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0005737	cytoplasm
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.74	EC:3.1.26.4	GO:0004523
0.34	KEGG:R07364	GO:0010309

tr|T1EM19|T1EM19_HELRO
Uncharacterized protein
Search

0.82	LOW QUALITY PROTEIN: protein kinase C and casein kinase substrate in neurons protein 1-like

0.72	GO:0097320	plasma membrane tubulation
0.62	GO:0030036	actin cytoskeleton organization
0.60	GO:0070836	caveola assembly
0.54	GO:0048666	neuron development
0.52	GO:0097435	supramolecular fiber organization
0.52	GO:0016310	phosphorylation
0.46	GO:0030100	regulation of endocytosis
0.45	GO:0007053	spindle assembly involved in male meiosis
0.45	GO:0036090	cleavage furrow ingression
0.44	GO:0045887	positive regulation of synaptic growth at neuromuscular junction

0.54	GO:0016301	kinase activity
0.45	GO:0008289	lipid binding
0.41	GO:0042802	identical protein binding
0.41	GO:0045296	cadherin binding
0.41	GO:0008092	cytoskeletal protein binding
0.37	GO:0043168	anion binding
0.34	GO:0005096	GTPase activator activity
0.32	GO:0046872	metal ion binding

0.46	GO:0098590	plasma membrane region
0.45	GO:0071212	subsynaptic reticulum
0.44	GO:0005768	endosome
0.43	GO:0032154	cleavage furrow
0.43	GO:0030496	midbody
0.41	GO:0098794	postsynapse
0.41	GO:0045121	membrane raft
0.41	GO:0016607	nuclear speck
0.40	GO:0044433	cytoplasmic vesicle part
0.40	GO:0030054	cell junction

tr|T1EM20|T1EM20_HELRO
Uncharacterized protein
Search

TBC1D22A

0.77	TBC1 domain family member 22B

0.63	GO:0031338	regulation of vesicle fusion
0.63	GO:0090630	activation of GTPase activity
0.54	GO:0006886	intracellular protein transport
0.44	GO:1902017	regulation of cilium assembly
0.38	GO:0033522	histone H2A ubiquitination
0.38	GO:0033523	histone H2B ubiquitination
0.38	GO:0045739	positive regulation of DNA repair
0.37	GO:0010212	response to ionizing radiation
0.37	GO:0080009	mRNA methylation
0.37	GO:0043401	steroid hormone mediated signaling pathway

0.85	GO:0071889	14-3-3 protein binding
0.61	GO:0017137	Rab GTPase binding
0.59	GO:0005096	GTPase activator activity
0.55	GO:0042803	protein homodimerization activity
0.37	GO:0004483	mRNA (nucleoside-2'-O-)-methyltransferase activity
0.37	GO:0043130	ubiquitin binding
0.37	GO:0042393	histone binding
0.36	GO:0003682	chromatin binding
0.36	GO:0004842	ubiquitin-protein transferase activity
0.35	GO:0004252	serine-type endopeptidase activity

0.53	GO:0012505	endomembrane system
0.39	GO:0005622	intracellular
0.37	GO:0030496	midbody
0.35	GO:1990234	transferase complex
0.35	GO:0043227	membrane-bounded organelle
0.34	GO:0043228	non-membrane-bounded organelle
0.34	GO:0044422	organelle part

0.37	EC:2.1.1.57	GO:0004483
0.36	KEGG:R03876	GO:0004842

tr|T1EM21|T1EM21_HELRO
Uncharacterized protein
Search

UBL5

0.78	Ubiquitin protein 5

0.65	GO:1903955	positive regulation of protein targeting to mitochondrion
0.62	GO:0034126	positive regulation of MyD88-dependent toll-like receptor signaling pathway
0.57	GO:0000398	mRNA splicing, via spliceosome
0.48	GO:0036211	protein modification process
0.45	GO:0044267	cellular protein metabolic process
0.43	GO:0034514	mitochondrial unfolded protein response
0.41	GO:0006013	mannose metabolic process
0.38	GO:0010628	positive regulation of gene expression
0.35	GO:0015992	proton transport
0.34	GO:0055085	transmembrane transport

0.63	GO:0031386	protein tag
0.40	GO:0004559	alpha-mannosidase activity
0.38	GO:0030246	carbohydrate binding
0.37	GO:0046872	metal ion binding
0.35	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.35	GO:0005515	protein binding

0.49	GO:0005634	nucleus
0.46	GO:0005737	cytoplasm
0.39	GO:0005667	transcription factor complex
0.37	GO:0033176	proton-transporting V-type ATPase complex
0.37	GO:0044446	intracellular organelle part
0.36	GO:0098805	whole membrane
0.36	GO:0098588	bounding membrane of organelle

0.40

EC:3.2.1.24

GO:0004559

tr|T1EM22|T1EM22_HELRO
Uncharacterized protein
Search

RAD1

0.86	DNA damage checkpoint control protein rad1

0.81	GO:0000077	DNA damage checkpoint
0.50	GO:0051598	meiotic recombination checkpoint
0.48	GO:0071479	cellular response to ionizing radiation
0.45	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.44	GO:0006281	DNA repair
0.38	GO:0021762	substantia nigra development
0.34	GO:0033314	mitotic DNA replication checkpoint
0.34	GO:0000723	telomere maintenance
0.33	GO:0006614	SRP-dependent cotranslational protein targeting to membrane

0.49	GO:0004527	exonuclease activity
0.47	GO:0003684	damaged DNA binding
0.39	GO:0004536	deoxyribonuclease activity
0.33	GO:0005047	signal recognition particle binding
0.32	GO:0003924	GTPase activity
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005634	nucleus
0.49	GO:0000793	condensed chromosome
0.47	GO:0031974	membrane-enclosed lumen
0.46	GO:0044427	chromosomal part
0.42	GO:0043234	protein complex
0.33	GO:0030867	rough endoplasmic reticulum membrane

tr|T1EM23|T1EM23_HELRO
Uncharacterized protein
Search

WLS

0.95	Wntless Wnt ligand secretion mediator

0.77	GO:0016055	Wnt signaling pathway
0.59	GO:0061357	positive regulation of Wnt protein secretion
0.59	GO:0061355	Wnt protein secretion
0.56	GO:0030177	positive regulation of Wnt signaling pathway
0.52	GO:0003002	regionalization
0.51	GO:0060828	regulation of canonical Wnt signaling pathway
0.50	GO:0031017	exocrine pancreas development
0.50	GO:0048729	tissue morphogenesis
0.50	GO:0009790	embryo development
0.49	GO:0030901	midbrain development

0.85	GO:0017147	Wnt-protein binding
0.39	GO:0031852	mu-type opioid receptor binding
0.33	GO:0004871	signal transducer activity

0.53	GO:0005769	early endosome
0.51	GO:0098791	Golgi subcompartment
0.46	GO:0031302	intrinsic component of endosome membrane
0.45	GO:0030285	integral component of synaptic vesicle membrane
0.44	GO:0042734	presynaptic membrane
0.43	GO:0031594	neuromuscular junction
0.43	GO:0005771	multivesicular body
0.42	GO:0045211	postsynaptic membrane
0.42	GO:0005789	endoplasmic reticulum membrane
0.42	GO:0070062	extracellular exosome

tr|T1EM24|T1EM24_HELRO
Uncharacterized protein
Search

UBLCP1

0.96	Ubiquitin like domain containing CTD phosphatase 1

0.72

GO:0006470

protein dephosphorylation

0.72	GO:0004721	phosphoprotein phosphatase activity
0.33	GO:0005515	protein binding
0.32	GO:0046872	metal ion binding

0.61	GO:0005634	nucleus
0.46	GO:0031974	membrane-enclosed lumen
0.43	GO:0043232	intracellular non-membrane-bounded organelle
0.42	GO:0044446	intracellular organelle part

0.72

GO:0004721

tr|T1EM25|T1EM25_HELRO
Uncharacterized protein
Search

LDHB

0.55	L-lactate dehydrogenase B chain

0.60	GO:0005975	carbohydrate metabolic process
0.57	GO:0019752	carboxylic acid metabolic process
0.53	GO:0055114	oxidation-reduction process
0.37	GO:0006757	ATP generation from ADP
0.37	GO:0009737	response to abscisic acid
0.36	GO:0009651	response to salt stress
0.36	GO:0019362	pyridine nucleotide metabolic process
0.35	GO:1901575	organic substance catabolic process
0.34	GO:0001666	response to hypoxia

0.81	GO:0004459	L-lactate dehydrogenase activity
0.35	GO:0042802	identical protein binding

0.48	GO:0005737	cytoplasm
0.36	GO:0043209	myelin sheath
0.36	GO:0045121	membrane raft
0.33	GO:0005886	plasma membrane
0.33	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.81

EC:1.1.1.27

GO:0004459

tr|T1EM26|T1EM26_HELRO
Uncharacterized protein
Search

RAP2C

0.96	RAP2C, member of RAS oncogene family

0.61	GO:0007165	signal transduction
0.52	GO:0031954	positive regulation of protein autophosphorylation
0.52	GO:0090557	establishment of endothelial intestinal barrier
0.50	GO:0030336	negative regulation of cell migration
0.49	GO:0061097	regulation of protein tyrosine kinase activity
0.41	GO:0030033	microvillus assembly
0.40	GO:2001141	regulation of RNA biosynthetic process
0.38	GO:0048814	regulation of dendrite morphogenesis
0.38	GO:0046328	regulation of JNK cascade
0.38	GO:0072659	protein localization to plasma membrane

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0003713	transcription coactivator activity
0.35	GO:0000287	magnesium ion binding
0.34	GO:0044548	S100 protein binding
0.34	GO:0031625	ubiquitin protein ligase binding
0.33	GO:0015631	tubulin binding

0.52	GO:0055038	recycling endosome membrane
0.49	GO:0044291	cell-cell contact zone
0.48	GO:0005923	bicellular tight junction
0.45	GO:0005829	cytosol
0.40	GO:0005886	plasma membrane
0.35	GO:0070062	extracellular exosome
0.35	GO:0030131	clathrin adaptor complex
0.34	GO:0070821	tertiary granule membrane

tr|T1EM27|T1EM27_HELRO
Uncharacterized protein
Search

HINT2

0.42	Histidine triad nucleotide-binding protein 1

0.41	GO:0016226	iron-sulfur cluster assembly
0.37	GO:0044240	multicellular organismal lipid catabolic process
0.36	GO:2000757	negative regulation of peptidyl-lysine acetylation
0.34	GO:0016310	phosphorylation

0.41	GO:0008199	ferric iron binding
0.35	GO:0047710	bis(5'-adenosyl)-triphosphatase activity
0.34	GO:0016301	kinase activity

0.42	GO:0009507	chloroplast
0.35	GO:0005730	nucleolus
0.34	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.35	EC:3.6.1.29	GO:0047710
0.35	KEGG:R00187	GO:0047710

tr|T1EM28|T1EM28_HELRO
Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase
Search

FTSJ1

0.68	Cell division protein (Fragment)

0.74	GO:0002128	tRNA nucleoside ribose methylation
0.71	GO:0002181	cytoplasmic translation
0.49	GO:0051301	cell division

0.74

GO:0008175

tRNA methyltransferase activity

0.46

GO:0005737

cytoplasm

0.74

GO:0008175

tr|T1EM29|T1EM29_HELRO
Uncharacterized protein
Search

0.65	T-box transcription factor TBX2

0.58	GO:0006351	transcription, DNA-templated
0.58	GO:0060596	mammary placode formation
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:0090398	cellular senescence
0.57	GO:0042693	muscle cell fate commitment
0.56	GO:0010468	regulation of gene expression
0.56	GO:0003205	cardiac chamber development
0.56	GO:0042733	embryonic digit morphogenesis
0.56	GO:0048568	embryonic organ development

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.51	GO:0001067	regulatory region nucleic acid binding
0.44	GO:0001102	RNA polymerase II activating transcription factor binding

0.61	GO:0005634	nucleus
0.47	GO:0005667	transcription factor complex
0.30	GO:0016021	integral component of membrane

tr|T1EM30|T1EM30_HELRO
Uncharacterized protein
Search

TMEM30B

0.77	Cell cycle control protein 50B

0.41	GO:0015914	phospholipid transport
0.40	GO:0051666	actin cortical patch localization
0.40	GO:0034204	lipid translocation
0.39	GO:0042147	retrograde transport, endosome to Golgi
0.37	GO:0006897	endocytosis
0.37	GO:0006886	intracellular protein transport
0.34	GO:0051301	cell division
0.34	GO:0010570	regulation of filamentous growth
0.33	GO:0017148	negative regulation of translation
0.30	GO:0008152	metabolic process

0.39	GO:0004012	phospholipid-translocating ATPase activity
0.34	GO:0030597	RNA glycosylase activity
0.33	GO:0070569	uridylyltransferase activity
0.33	GO:0140102	catalytic activity, acting on a rRNA
0.32	GO:0005515	protein binding

0.41	GO:1990530	Cdc50p-Drs2p complex
0.40	GO:0005802	trans-Golgi network
0.40	GO:0031902	late endosome membrane
0.37	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.39

EC:3.6.3.1

GO:0004012

tr|T1EM31|T1EM31_HELRO
Uncharacterized protein
Search

CTH

0.47	Cystathionine gamma-lyase (inferred by orthology to a human protein)

0.51	GO:0019346	transsulfuration
0.49	GO:0019343	cysteine biosynthetic process via cystathionine
0.48	GO:1904831	positive regulation of aortic smooth muscle cell differentiation
0.47	GO:0044524	protein sulfhydration
0.47	GO:0018272	protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine
0.45	GO:0051289	protein homotetramerization
0.43	GO:0071266	'de novo' L-methionine biosynthetic process
0.43	GO:1990823	response to leukemia inhibitory factor
0.43	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.43	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling

0.67	GO:0030170	pyridoxal phosphate binding
0.56	GO:0016829	lyase activity
0.45	GO:0003962	cystathionine gamma-synthase activity
0.42	GO:0042802	identical protein binding
0.35	GO:0005516	calmodulin binding

0.35	GO:0005737	cytoplasm
0.34	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.56

EC:4

GO:0016829

tr|T1EM32|T1EM32_HELRO
Uncharacterized protein
Search

PABPN1

0.82	Polyadenylate-binding protein nuclear 1

0.86	GO:1904247	positive regulation of polynucleotide adenylyltransferase activity
0.45	GO:0071222	cellular response to lipopolysaccharide
0.44	GO:0042981	regulation of apoptotic process
0.44	GO:0000165	MAPK cascade
0.43	GO:0006915	apoptotic process
0.43	GO:0016973	poly(A)+ mRNA export from nucleus
0.40	GO:0043069	negative regulation of programmed cell death
0.39	GO:0031124	mRNA 3'-end processing
0.38	GO:0043631	RNA polyadenylation
0.36	GO:0038034	signal transduction in absence of ligand

0.59	GO:0003723	RNA binding
0.43	GO:0070063	RNA polymerase binding
0.42	GO:0097718	disordered domain specific binding
0.40	GO:0046982	protein heterodimerization activity
0.40	GO:0042802	identical protein binding
0.36	GO:0043621	protein self-association

0.46	GO:0042405	nuclear inclusion body
0.42	GO:0097136	Bcl-2 family protein complex
0.39	GO:0030529	intracellular ribonucleoprotein complex
0.37	GO:0016607	nuclear speck
0.35	GO:0005741	mitochondrial outer membrane

tr|T1EM33|T1EM33_HELRO
Uncharacterized protein
Search

0.37	Single-stranded DNA-binding protein 3

0.48	GO:0021547	midbrain-hindbrain boundary initiation
0.47	GO:0021501	prechordal plate formation
0.47	GO:2000744	positive regulation of anterior head development
0.45	GO:0060323	head morphogenesis
0.45	GO:0045944	positive regulation of transcription by RNA polymerase II
0.45	GO:0002244	hematopoietic progenitor cell differentiation
0.43	GO:0008284	positive regulation of cell proliferation
0.42	GO:0006366	transcription by RNA polymerase II
0.41	GO:0006461	protein complex assembly

0.74	GO:0003697	single-stranded DNA binding
0.43	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.43	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.33	GO:0005515	protein binding

0.38	GO:0005634	nucleus
0.38	GO:0043234	protein complex
0.32	GO:0005739	mitochondrion

tr|T1EM34|T1EM34_HELRO
Signal transducer and activator of transcription
Search

0.70	Signal transducer and activator of transcription

0.86	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway
0.57	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.48	GO:0008284	positive regulation of cell proliferation
0.47	GO:0051240	positive regulation of multicellular organismal process
0.46	GO:0046544	development of secondary male sexual characteristics
0.46	GO:0046543	development of secondary female sexual characteristics
0.46	GO:0001553	luteinization

0.64	GO:0004871	signal transducer activity
0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.44	GO:0035259	glucocorticoid receptor binding
0.41	GO:0001067	regulatory region nucleic acid binding
0.39	GO:0046983	protein dimerization activity
0.36	GO:0003682	chromatin binding
0.35	GO:0004713	protein tyrosine kinase activity

0.61	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.40	GO:0070013	intracellular organelle lumen
0.38	GO:0044446	intracellular organelle part
0.30	GO:0044425	membrane part

0.35

EC:2.7.10

GO:0004713

tr|T1EM35|T1EM35_HELRO
Uncharacterized protein
Search

0.81	dynein heavy chain 1, axonemal-like

0.83	GO:0003341	cilium movement
0.54	GO:0036159	inner dynein arm assembly
0.52	GO:0007288	sperm axoneme assembly
0.43	GO:0060285	cilium-dependent cell motility

0.75	GO:0003777	microtubule motor activity
0.60	GO:0016887	ATPase activity
0.54	GO:0045503	dynein light chain binding
0.53	GO:0051959	dynein light intermediate chain binding
0.53	GO:0045505	dynein intermediate chain binding
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005509	calcium ion binding

0.84	GO:0005858	axonemal dynein complex
0.52	GO:0036126	sperm flagellum
0.38	GO:0005874	microtubule
0.30	GO:0031224	intrinsic component of membrane

0.60

EC:3.6.1.3

GO:0016887

tr|T1EM36|T1EM36_HELRO
Uncharacterized protein
Search

ZNF501

0.72	Zinc finger protein 501

0.42	GO:2001141	regulation of RNA biosynthetic process
0.42	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.41	GO:0010468	regulation of gene expression
0.40	GO:0001654	eye development
0.37	GO:0046665	amnioserosa maintenance
0.37	GO:0035160	maintenance of epithelial integrity, open tracheal system
0.37	GO:0072499	photoreceptor cell axon guidance
0.36	GO:0007390	germ-band shortening
0.36	GO:0007362	terminal region determination
0.36	GO:0008594	photoreceptor cell morphogenesis

0.51	GO:0003676	nucleic acid binding
0.41	GO:0046872	metal ion binding
0.37	GO:0140110	transcription regulator activity
0.33	GO:0008201	heparin binding
0.33	GO:0008061	chitin binding
0.33	GO:0005515	protein binding
0.32	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.32	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0004672	protein kinase activity

0.42	GO:0005634	nucleus
0.39	GO:0005829	cytosol
0.39	GO:0070013	intracellular organelle lumen
0.38	GO:0043232	intracellular non-membrane-bounded organelle
0.37	GO:0044446	intracellular organelle part
0.34	GO:0099512	supramolecular fiber
0.32	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.32

EC:3.2.1

GO:0004553

tr|T1EM37|T1EM37_HELRO
Uncharacterized protein
Search

0.39	GO:0036211	protein modification process
0.39	GO:0006817	phosphate ion transport
0.38	GO:0044267	cellular protein metabolic process
0.38	GO:0065007	biological regulation
0.37	GO:0006629	lipid metabolic process
0.37	GO:0050896	response to stimulus
0.37	GO:0006325	chromatin organization
0.36	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.36	GO:0023052	signaling
0.36	GO:0055085	transmembrane transport

0.39	GO:0005315	inorganic phosphate transmembrane transporter activity
0.38	GO:0016787	hydrolase activity
0.38	GO:0140096	catalytic activity, acting on a protein
0.37	GO:0003676	nucleic acid binding
0.36	GO:0046872	metal ion binding
0.36	GO:0043168	anion binding
0.36	GO:0017076	purine nucleotide binding
0.36	GO:0097367	carbohydrate derivative binding
0.36	GO:0008144	drug binding
0.36	GO:0005515	protein binding

0.38	GO:0005634	nucleus
0.35	GO:0005774	vacuolar membrane
0.34	GO:0044459	plasma membrane part
0.34	GO:0030688	preribosome, small subunit precursor
0.34	GO:0012505	endomembrane system
0.34	GO:1990225	rhoptry neck
0.34	GO:0031225	anchored component of membrane
0.34	GO:0005938	cell cortex
0.34	GO:0005694	chromosome
0.34	GO:0005764	lysosome

0.38	EC:3	GO:0016787
0.32	KEGG:R03165	GO:0004852

tr|T1EM38|T1EM38_HELRO
Uncharacterized protein
Search

SURF4

0.97	Surfeit gene 4, like

0.47	GO:0007030	Golgi organization
0.45	GO:0010638	positive regulation of organelle organization
0.37	GO:0034498	early endosome to Golgi transport
0.36	GO:0032527	protein exit from endoplasmic reticulum
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER

0.34

GO:0005515

protein binding

0.48	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.39	GO:0005789	endoplasmic reticulum membrane
0.38	GO:0000139	Golgi membrane
0.35	GO:0035577	azurophil granule membrane
0.34	GO:0030133	transport vesicle
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1EM39|T1EM39_HELRO
Uncharacterized protein
Search

0.67	C-terminal binding protein, isoform B

0.53	GO:0055114	oxidation-reduction process
0.36	GO:1903507	negative regulation of nucleic acid-templated transcription
0.35	GO:0016360	sensory organ precursor cell fate determination
0.35	GO:0022416	chaeta development
0.34	GO:0001700	embryonic development via the syncytial blastoderm
0.34	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.34	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.34	GO:0035220	wing disc development
0.34	GO:0043044	ATP-dependent chromatin remodeling
0.34	GO:0045944	positive regulation of transcription by RNA polymerase II

0.68	GO:0051287	NAD binding
0.66	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
0.38	GO:0003714	transcription corepressor activity
0.37	GO:0042803	protein homodimerization activity
0.34	GO:0070491	repressing transcription factor binding
0.34	GO:0003713	transcription coactivator activity

0.36	GO:0005829	cytosol
0.35	GO:0005634	nucleus
0.34	GO:0005700	polytene chromosome
0.33	GO:0000785	chromatin
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:1904949	ATPase complex

0.66

EC:1.1.1

GO:0016616

tr|T1EM40|T1EM40_HELRO
Uncharacterized protein
Search

0.65	ADP-ribosylation factorB-A

0.35	GO:0007059	chromosome segregation
0.35	GO:0032418	lysosome localization
0.33	GO:0005975	carbohydrate metabolic process
0.33	GO:0051301	cell division
0.33	GO:0007049	cell cycle

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0004415	hyalurononglucosaminidase activity
0.35	GO:0043014	alpha-tubulin binding
0.34	GO:0048487	beta-tubulin binding
0.32	GO:0017111	nucleoside-triphosphatase activity

0.45	GO:0005622	intracellular
0.35	GO:0098805	whole membrane
0.35	GO:0098588	bounding membrane of organelle
0.34	GO:0030496	midbody
0.33	GO:0031982	vesicle
0.33	GO:0043228	non-membrane-bounded organelle
0.33	GO:0012505	endomembrane system

0.36

EC:3.2.1.35

GO:0004415

tr|T1EM41|T1EM41_HELRO
Uncharacterized protein
Search

0.38	Transmembrane protein 26

0.33	GO:0008641	ubiquitin-like modifier activating enzyme activity
0.32	GO:0016779	nucleotidyltransferase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0031224

intrinsic component of membrane

0.32

EC:2.7.7

GO:0016779

tr|T1EM42|T1EM42_HELRO
Uncharacterized protein
Search

0.42	Transcriptional repressor scratch 1

0.52	GO:0000122	negative regulation of transcription by RNA polymerase II
0.50	GO:0048699	generation of neurons
0.49	GO:0036445	neuronal stem cell division
0.48	GO:0098722	asymmetric stem cell division
0.48	GO:0072089	stem cell proliferation
0.48	GO:0061351	neural precursor cell proliferation
0.47	GO:0045595	regulation of cell differentiation
0.46	GO:0045165	cell fate commitment
0.45	GO:0007417	central nervous system development
0.45	GO:0030334	regulation of cell migration

0.52	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.51	GO:0003676	nucleic acid binding
0.48	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.38	GO:0005507	copper ion binding
0.34	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.33	GO:0003682	chromatin binding
0.32	GO:0005515	protein binding

0.45	GO:0005634	nucleus
0.42	GO:0005667	transcription factor complex
0.39	GO:0070013	intracellular organelle lumen
0.36	GO:0044446	intracellular organelle part
0.33	GO:0005694	chromosome
0.32	GO:0005737	cytoplasm

tr|T1EM43|T1EM43_HELRO
Uncharacterized protein
Search

0.80	Actin-interacting protein 1

0.80	GO:0045214	sarcomere organization
0.78	GO:0030042	actin filament depolymerization
0.76	GO:0030834	regulation of actin filament depolymerization
0.74	GO:0001736	establishment of planar polarity
0.74	GO:0035317	imaginal disc-derived wing hair organization
0.72	GO:0007298	border follicle cell migration
0.72	GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation
0.61	GO:1901881	positive regulation of protein depolymerization
0.57	GO:1902905	positive regulation of supramolecular fiber organization
0.57	GO:0051495	positive regulation of cytoskeleton organization

0.53	GO:0051015	actin filament binding
0.40	GO:0003743	translation initiation factor activity
0.38	GO:0004402	histone acetyltransferase activity
0.37	GO:0003700	DNA binding transcription factor activity
0.36	GO:0030554	adenyl nucleotide binding
0.36	GO:0003677	DNA binding
0.35	GO:0097367	carbohydrate derivative binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0008144	drug binding

0.63	GO:0005856	cytoskeleton
0.52	GO:0044448	cell cortex part
0.50	GO:0099512	supramolecular fiber
0.46	GO:0005779	integral component of peroxisomal membrane
0.45	GO:0043209	myelin sheath
0.44	GO:0005911	cell-cell junction
0.38	GO:0005886	plasma membrane
0.37	GO:0005634	nucleus

0.38

GO:0004402

tr|T1EM44|T1EM44_HELRO
Uncharacterized protein
Search

0.73	V-ATPase holoenzyme subunit B mRNA

0.75	GO:0015991	ATP hydrolysis coupled proton transport
0.62	GO:0046034	ATP metabolic process
0.54	GO:0045851	pH reduction
0.50	GO:0055074	calcium ion homeostasis
0.50	GO:1902906	proteasome storage granule assembly
0.49	GO:0051453	regulation of intracellular pH
0.46	GO:0072503	cellular divalent inorganic cation homeostasis
0.45	GO:0007588	excretion
0.44	GO:0006875	cellular metal ion homeostasis
0.44	GO:0001503	ossification

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0046961	proton-transporting ATPase activity, rotational mechanism
0.35	GO:0032403	protein complex binding
0.34	GO:0005234	extracellularly glutamate-gated ion channel activity
0.33	GO:0004970	ionotropic glutamate receptor activity
0.33	GO:0004298	threonine-type endopeptidase activity

0.80	GO:0033180	proton-transporting V-type ATPase, V1 domain
0.51	GO:0016471	vacuolar proton-transporting V-type ATPase complex
0.48	GO:1990816	vacuole-mitochondrion membrane contact site
0.46	GO:0010494	cytoplasmic stress granule
0.46	GO:0000329	fungal-type vacuole membrane
0.45	GO:0005902	microvillus
0.44	GO:0016323	basolateral plasma membrane
0.43	GO:0016324	apical plasma membrane
0.43	GO:0016328	lateral plasma membrane
0.40	GO:0005829	cytosol

0.33

EC:3.4.25

GO:0004298

tr|T1EM45|T1EM45_HELRO
Uncharacterized protein
Search

tr|T1EM46|T1EM46_HELRO
mRNA-capping enzyme
Search

RNGTT

0.85	mRNA-capping enzyme

0.83	GO:0098507	polynucleotide 5' dephosphorylation
0.75	GO:0006370	7-methylguanosine mRNA capping
0.73	GO:0035335	peptidyl-tyrosine dephosphorylation
0.34	GO:0006366	transcription by RNA polymerase II
0.34	GO:0007018	microtubule-based movement
0.34	GO:1903963	arachidonate transport
0.34	GO:0032309	icosanoid secretion
0.33	GO:0010628	positive regulation of gene expression
0.33	GO:0016032	viral process
0.33	GO:0006644	phospholipid metabolic process

0.84	GO:0004484	mRNA guanylyltransferase activity
0.84	GO:0004651	polynucleotide 5'-phosphatase activity
0.77	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.74	GO:0004725	protein tyrosine phosphatase activity
0.61	GO:0032550	purine ribonucleoside binding
0.61	GO:0019001	guanyl nucleotide binding
0.53	GO:0050355	triphosphatase activity
0.51	GO:0032553	ribonucleotide binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.34	GO:0016459	myosin complex
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0005576	extracellular region

0.84	EC:2.7.7.50	GO:0004484
0.53	KEGG:R00138	GO:0050355

tr|T1EM47|T1EM47_HELRO
Uncharacterized protein
Search

RALGAPA2

0.59	Ral GTPase activating protein catalytic alpha subunit 2

0.76	GO:0051056	regulation of small GTPase mediated signal transduction
0.76	GO:0043547	positive regulation of GTPase activity
0.44	GO:0007420	brain development
0.37	GO:0032484	Ral protein signal transduction
0.36	GO:0060178	regulation of exocyst localization

0.76	GO:0005096	GTPase activator activity
0.36	GO:0046982	protein heterodimerization activity

0.61	GO:0005634	nucleus
0.42	GO:0005829	cytosol
0.38	GO:0005886	plasma membrane
0.35	GO:0005615	extracellular space
0.30	GO:0044425	membrane part

tr|T1EM48|T1EM48_HELRO
Uncharacterized protein
Search

0.64	Ribosomal protein L44

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.35	GO:0043009	chordate embryonic development
0.35	GO:0051726	regulation of cell cycle

0.64	GO:0003735	structural constituent of ribosome
0.33	GO:0046872	metal ion binding

0.61	GO:0005840	ribosome
0.36	GO:0044445	cytosolic part
0.34	GO:0044446	intracellular organelle part

tr|T1EM49|T1EM49_HELRO
Uncharacterized protein
Search

CYP51A1

0.76	Cytochrome P450 family 51 subfamily A member 1

0.58	GO:0070988	demethylation
0.58	GO:0001878	response to yeast
0.54	GO:0033488	cholesterol biosynthetic process via 24,25-dihydrolanosterol
0.53	GO:0055114	oxidation-reduction process
0.35	GO:0032259	methylation

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.68	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.60	GO:0032451	demethylase activity
0.35	GO:0008168	methyltransferase activity

0.58	GO:0005783	endoplasmic reticulum
0.39	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

0.68

EC:1.14

GO:0016705

tr|T1EM50|T1EM50_HELRO
Uncharacterized protein
Search

BYSL

0.86	Essential nuclear protein 1

0.73	GO:0001829	trophectodermal cell differentiation
0.70	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.67	GO:0008283	cell proliferation
0.42	GO:0016973	poly(A)+ mRNA export from nucleus
0.42	GO:0000479	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.41	GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.40	GO:0007155	cell adhesion
0.39	GO:0006836	neurotransmitter transport
0.38	GO:0071347	cellular response to interleukin-1
0.38	GO:0007565	female pregnancy

0.41	GO:0030515	snoRNA binding
0.39	GO:0005328	neurotransmitter:sodium symporter activity
0.38	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups
0.37	GO:0005254	chloride channel activity
0.35	GO:0005515	protein binding

0.68	GO:0045177	apical part of cell
0.65	GO:0005730	nucleolus
0.45	GO:0005737	cytoplasm
0.42	GO:0030688	preribosome, small subunit precursor
0.41	GO:0030686	90S preribosome
0.37	GO:0034707	chloride channel complex
0.36	GO:0005874	microtubule
0.36	GO:0005654	nucleoplasm
0.36	GO:0042995	cell projection

0.38

EC:2.5 EC:2.5.1

GO:0016765

tr|T1EM51|T1EM51_HELRO
Uncharacterized protein
Search

CNOT1

0.59	CCR4-NOT transcription complex subunit 1

0.86	GO:0048387	negative regulation of retinoic acid receptor signaling pathway
0.85	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway
0.85	GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
0.85	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly
0.85	GO:2000036	regulation of stem cell population maintenance
0.80	GO:0035195	gene silencing by miRNA
0.76	GO:0000122	negative regulation of transcription by RNA polymerase II
0.72	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic
0.63	GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
0.46	GO:0001829	trophectodermal cell differentiation

0.85	GO:0070016	armadillo repeat domain binding
0.85	GO:0042974	retinoic acid receptor binding
0.85	GO:0030331	estrogen receptor binding
0.82	GO:0004535	poly(A)-specific ribonuclease activity
0.81	GO:0032947	protein complex scaffold activity
0.38	GO:0003723	RNA binding
0.36	GO:0046982	protein heterodimerization activity

0.82	GO:0030014	CCR4-NOT complex
0.81	GO:0000932	P-body
0.66	GO:0005829	cytosol
0.44	GO:0031903	microbody membrane
0.43	GO:0044439	peroxisomal part
0.42	GO:0005615	extracellular space
0.41	GO:0005634	nucleus

0.82

EC:3.1.13.4

GO:0004535

tr|T1EM52|T1EM52_HELRO
Uncharacterized protein
Search

RAB9B

0.84	Ras-related protein Rab-9A

0.46	GO:0042147	retrograde transport, endosome to Golgi
0.43	GO:0052405	negative regulation by host of symbiont molecular function
0.42	GO:0045921	positive regulation of exocytosis
0.40	GO:0032880	regulation of protein localization
0.39	GO:0015031	protein transport
0.36	GO:0043312	neutrophil degranulation

0.67	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0042802	identical protein binding

0.47	GO:0045335	phagocytic vesicle
0.43	GO:0030666	endocytic vesicle membrane
0.42	GO:0005829	cytosol
0.42	GO:0042470	melanosome
0.41	GO:0005770	late endosome
0.40	GO:0005764	lysosome
0.38	GO:0000139	Golgi membrane
0.38	GO:0005789	endoplasmic reticulum membrane
0.37	GO:0070062	extracellular exosome
0.37	GO:0005886	plasma membrane

tr|T1EM53|T1EM53_HELRO
Uncharacterized protein
Search

RPL11

0.64	Large subunit ribosomal protein L11e

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.42	GO:0020027	hemoglobin metabolic process
0.42	GO:0048821	erythrocyte development
0.41	GO:0042593	glucose homeostasis
0.40	GO:0043009	chordate embryonic development
0.40	GO:0006915	apoptotic process
0.38	GO:0000027	ribosomal large subunit assembly

0.64	GO:0003735	structural constituent of ribosome
0.36	GO:0003723	RNA binding
0.35	GO:0005549	odorant binding
0.35	GO:0004984	olfactory receptor activity
0.34	GO:0003684	damaged DNA binding
0.33	GO:0005515	protein binding

0.61	GO:0005840	ribosome
0.44	GO:0005703	polytene chromosome puff
0.41	GO:0005730	nucleolus
0.40	GO:0000228	nuclear chromosome
0.37	GO:0044445	cytosolic part
0.34	GO:0070449	elongin complex
0.30	GO:0016020	membrane

tr|T1EM54|T1EM54_HELRO
Uncharacterized protein
Search

SET

0.96	SET nuclear proto-oncogene b

0.79	GO:0006334	nucleosome assembly
0.42	GO:0048884	neuromast development
0.38	GO:0043524	negative regulation of neuron apoptotic process
0.36	GO:0045892	negative regulation of transcription, DNA-templated
0.35	GO:0006468	protein phosphorylation
0.35	GO:0007165	signal transduction
0.35	GO:0035067	negative regulation of histone acetylation
0.34	GO:0031498	chromatin disassembly
0.34	GO:0032986	protein-DNA complex disassembly
0.34	GO:0043488	regulation of mRNA stability

0.38	GO:0017049	GTP-Rho binding
0.37	GO:0004674	protein serine/threonine kinase activity
0.34	GO:0004864	protein phosphatase inhibitor activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0042393	histone binding
0.33	GO:0003677	DNA binding

0.61	GO:0005634	nucleus
0.38	GO:0005811	lipid droplet
0.37	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0031974	membrane-enclosed lumen
0.36	GO:0005783	endoplasmic reticulum
0.35	GO:0005829	cytosol
0.35	GO:0044446	intracellular organelle part
0.35	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

0.37

GO:0004674

tr|T1EM55|T1EM55_HELRO
Uncharacterized protein
Search

ATG101

0.76	RAC serine/threonine-protein kinase-like Protein

0.77	GO:0006914	autophagy
0.53	GO:0007033	vacuole organization
0.49	GO:0070925	organelle assembly
0.34	GO:0016241	regulation of macroautophagy
0.34	GO:0016310	phosphorylation
0.34	GO:0036211	protein modification process
0.33	GO:0044267	cellular protein metabolic process
0.32	GO:0030001	metal ion transport
0.32	GO:0055085	transmembrane transport

0.48	GO:0032403	protein complex binding
0.48	GO:0042802	identical protein binding
0.34	GO:0016301	kinase activity
0.34	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.33	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0046873	metal ion transmembrane transporter activity

0.54	GO:0000407	phagophore assembly site
0.34	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0016773

tr|T1EM56|T1EM56_HELRO
Uncharacterized protein
Search

0.34

COLlagen

0.40	GO:0030198	extracellular matrix organization
0.39	GO:0007275	multicellular organism development
0.39	GO:0009888	tissue development
0.39	GO:0048589	developmental growth
0.38	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.38	GO:0009653	anatomical structure morphogenesis
0.38	GO:0007155	cell adhesion
0.38	GO:0071230	cellular response to amino acid stimulus
0.38	GO:0031099	regeneration
0.37	GO:0042060	wound healing

0.65	GO:0005201	extracellular matrix structural constituent
0.58	GO:0042302	structural constituent of cuticle
0.37	GO:0005509	calcium ion binding
0.36	GO:0048407	platelet-derived growth factor binding
0.34	GO:0005544	calcium-dependent phospholipid binding
0.34	GO:0008061	chitin binding
0.34	GO:0008233	peptidase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.65	GO:0005581	collagen trimer
0.59	GO:0005604	basement membrane
0.40	GO:0098645	collagen network
0.35	GO:0005615	extracellular space
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.34

GO:0008233

tr|T1EM57|T1EM57_HELRO
Uncharacterized protein
Search

XXYLT1

0.95	Xyloside xylosyltransferase 1

0.51	GO:0016266	O-glycan processing
0.34	GO:0043547	positive regulation of GTPase activity

0.59	GO:0016757	transferase activity, transferring glycosyl groups
0.46	GO:0030145	manganese ion binding
0.43	GO:0000287	magnesium ion binding
0.34	GO:0005096	GTPase activator activity
0.33	GO:0005515	protein binding

0.47

GO:0030176

integral component of endoplasmic reticulum membrane

0.59

GO:0016757

tr|T1EM58|T1EM58_HELRO
Uncharacterized protein
Search

HOGA1

0.58	N-acetylneuraminate lyase

0.54	GO:0019470	4-hydroxyproline catabolic process
0.50	GO:0009436	glyoxylate catabolic process
0.49	GO:0042866	pyruvate biosynthetic process
0.49	GO:0033609	oxalate metabolic process
0.45	GO:0019877	diaminopimelate biosynthetic process
0.45	GO:0009089	lysine biosynthetic process via diaminopimelate
0.34	GO:0005975	carbohydrate metabolic process
0.33	GO:0015711	organic anion transport
0.32	GO:0055085	transmembrane transport

0.62	GO:0016829	lyase activity
0.46	GO:0042803	protein homodimerization activity
0.33	GO:0008514	organic anion transmembrane transporter activity

0.42	GO:0005739	mitochondrion
0.35	GO:0070062	extracellular exosome
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0005887	integral component of plasma membrane
0.32	GO:0044446	intracellular organelle part

0.62

EC:4

GO:0016829

tr|T1EM59|T1EM59_HELRO
Uncharacterized protein
Search

0.42	Multidrug resistance-associated protein 1

0.54	GO:0055085	transmembrane transport
0.54	GO:0015723	bilirubin transport
0.52	GO:0042144	vacuole fusion, non-autophagic
0.48	GO:0010038	response to metal ion
0.48	GO:0006749	glutathione metabolic process
0.45	GO:0045454	cell redox homeostasis
0.37	GO:0015691	cadmium ion transport
0.32	GO:0055114	oxidation-reduction process

0.65	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0015127	bilirubin transmembrane transporter activity
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0015086	cadmium ion transmembrane transporter activity
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.33	GO:0005509	calcium ion binding

0.50	GO:0000329	fungal-type vacuole membrane
0.42	GO:0005887	integral component of plasma membrane
0.35	GO:0005856	cytoskeleton
0.34	GO:0016323	basolateral plasma membrane

0.34

GO:0032440

tr|T1EM60|T1EM60_HELRO
Uncharacterized protein
Search

tr|T1EM61|T1EM61_HELRO
Uncharacterized protein
Search

SNRPA1

0.79	Small nuclear ribonucleoprotein polypeptide A'

0.46	GO:0000398	mRNA splicing, via spliceosome
0.43	GO:0007283	spermatogenesis
0.41	GO:0006325	chromatin organization
0.35	GO:0035722	interleukin-12-mediated signaling pathway
0.35	GO:0040022	feminization of hermaphroditic germ-line
0.35	GO:0051729	germline cell cycle switching, mitotic to meiotic cell cycle
0.34	GO:0000278	mitotic cell cycle
0.34	GO:0006886	intracellular protein transport
0.33	GO:0022618	ribonucleoprotein complex assembly
0.33	GO:0006629	lipid metabolic process

0.51	GO:0030620	U2 snRNA binding
0.34	GO:0004806	triglyceride lipase activity
0.33	GO:0005515	protein binding

0.61	GO:0019013	viral nucleocapsid
0.58	GO:0030529	intracellular ribonucleoprotein complex
0.53	GO:0120114	Sm-like protein family complex
0.51	GO:0016607	nuclear speck
0.44	GO:1902494	catalytic complex
0.34	GO:0030176	integral component of endoplasmic reticulum membrane
0.33	GO:0005576	extracellular region

0.34

EC:3.1.1.3

GO:0004806

tr|T1EM62|T1EM62_HELRO
ER lumen protein-retaining receptor
Search

KDELR1

0.66	ER lumen protein-retaining receptor

0.84	GO:0006621	protein retention in ER lumen
0.65	GO:0015031	protein transport
0.51	GO:0002369	T cell cytokine production
0.51	GO:0070231	T cell apoptotic process
0.49	GO:0030217	T cell differentiation
0.40	GO:0016192	vesicle-mediated transport
0.35	GO:0046907	intracellular transport

0.84

GO:0046923

ER retention sequence binding

0.71	GO:0005789	endoplasmic reticulum membrane
0.51	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.48	GO:0005801	cis-Golgi network
0.45	GO:0005794	Golgi apparatus
0.40	GO:0030663	COPI-coated vesicle membrane
0.34	GO:0030133	transport vesicle
0.30	GO:0016021	integral component of membrane

tr|T1EM63|T1EM63_HELRO
Uncharacterized protein
Search

0.59	Fibrinogen C domain-containing protein 1-A

0.62	GO:0001568	blood vessel development
0.57	GO:0048646	anatomical structure formation involved in morphogenesis
0.54	GO:0048014	Tie signaling pathway
0.50	GO:0043066	negative regulation of apoptotic process
0.44	GO:0007420	brain development
0.43	GO:0007567	parturition
0.43	GO:0006508	proteolysis
0.41	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity
0.40	GO:0043537	negative regulation of blood vessel endothelial cell migration
0.40	GO:0043536	positive regulation of blood vessel endothelial cell migration

0.61	GO:0030971	receptor tyrosine kinase binding
0.43	GO:0008233	peptidase activity
0.41	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity
0.36	GO:0008641	ubiquitin-like modifier activating enzyme activity
0.36	GO:0008061	chitin binding
0.35	GO:0005509	calcium ion binding
0.34	GO:0030674	protein binding, bridging
0.34	GO:0050839	cell adhesion molecule binding
0.34	GO:0051087	chaperone binding
0.33	GO:0030554	adenyl nucleotide binding

0.50	GO:0005615	extracellular space
0.41	GO:1903561	extracellular vesicle
0.34	GO:0031091	platelet alpha granule
0.34	GO:0009897	external side of plasma membrane
0.34	GO:0005938	cell cortex
0.33	GO:0005783	endoplasmic reticulum
0.32	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.43

GO:0008233

tr|T1EM64|T1EM64_HELRO
Uncharacterized protein
Search

0.55	GO:0000733	DNA strand renaturation
0.52	GO:0008340	determination of adult lifespan
0.52	GO:0010212	response to ionizing radiation
0.49	GO:0000724	double-strand break repair via homologous recombination
0.46	GO:0042493	response to drug
0.34	GO:0051321	meiotic cell cycle
0.34	GO:0009408	response to heat
0.34	GO:0006470	protein dephosphorylation
0.34	GO:0006457	protein folding

0.55	GO:0036310	annealing helicase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0008094	DNA-dependent ATPase activity
0.36	GO:0004386	helicase activity
0.35	GO:0003677	DNA binding
0.34	GO:0031072	heat shock protein binding
0.34	GO:0004721	phosphoprotein phosphatase activity
0.34	GO:0051082	unfolded protein binding

0.47	GO:0005654	nucleoplasm
0.43	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0004721

tr|T1EM65|T1EM65_HELRO
Uncharacterized protein
Search

0.88	Caspase 3, apoptosis-related cysteine peptidase a

0.61	GO:0006508	proteolysis
0.55	GO:0097194	execution phase of apoptosis
0.52	GO:0051402	neuron apoptotic process
0.49	GO:0009411	response to UV
0.49	GO:0007507	heart development
0.46	GO:0051604	protein maturation
0.43	GO:0048696	regulation of collateral sprouting in absence of injury
0.43	GO:0043065	positive regulation of apoptotic process
0.43	GO:0071236	cellular response to antibiotic
0.42	GO:0072733	response to staurosporine

0.75	GO:0004197	cysteine-type endopeptidase activity
0.45	GO:0070001	aspartic-type peptidase activity
0.38	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity
0.34	GO:0005515	protein binding

0.38	GO:0005829	cytosol
0.36	GO:0005634	nucleus
0.33	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0043233	organelle lumen
0.33	GO:0031966	mitochondrial membrane
0.30	GO:0016021	integral component of membrane

0.75

EC:3.4.22

GO:0004197

tr|T1EM66|T1EM66_HELRO
Uncharacterized protein
Search

RPL12

0.73	Ribosomal protein L12

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.38	GO:0000027	ribosomal large subunit assembly

0.64	GO:0003735	structural constituent of ribosome
0.36	GO:0019843	rRNA binding
0.34	GO:0030246	carbohydrate binding
0.32	GO:0016787	hydrolase activity

0.61	GO:0005840	ribosome
0.37	GO:0044445	cytosolic part
0.35	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

0.32

GO:0016787

tr|T1EM67|T1EM67_HELRO
Uncharacterized protein
Search

RAB10

0.63	ADP ribosylation factor

0.48	GO:0032869	cellular response to insulin stimulus
0.47	GO:0097051	establishment of protein localization to endoplasmic reticulum membrane
0.46	GO:0071786	endoplasmic reticulum tubular network organization
0.46	GO:0016197	endosomal transport
0.45	GO:0016192	vesicle-mediated transport
0.45	GO:0048468	cell development
0.44	GO:0030182	neuron differentiation
0.43	GO:0072659	protein localization to plasma membrane
0.43	GO:0017157	regulation of exocytosis
0.43	GO:0120036	plasma membrane bounded cell projection organization

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0032561	guanyl ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0098641	cadherin binding involved in cell-cell adhesion
0.45	GO:0031489	myosin V binding
0.41	GO:0071532	ankyrin repeat binding
0.41	GO:0032794	GTPase activating protein binding

0.51	GO:0032593	insulin-responsive compartment
0.47	GO:0055037	recycling endosome
0.45	GO:0005794	Golgi apparatus
0.45	GO:0071782	endoplasmic reticulum tubular network
0.44	GO:0120025	plasma membrane bounded cell projection
0.43	GO:0005913	cell-cell adherens junction
0.43	GO:0070382	exocytic vesicle
0.42	GO:0005789	endoplasmic reticulum membrane
0.41	GO:0010008	endosome membrane
0.41	GO:0031045	dense core granule

tr|T1EM68|T1EM68_HELRO
Uncharacterized protein
Search

0.40	Tyrosine phosphatase type IVA

0.71	GO:0006470	protein dephosphorylation
0.48	GO:0043542	endothelial cell migration
0.47	GO:1901224	positive regulation of NIK/NF-kappaB signaling
0.46	GO:0043117	positive regulation of vascular permeability
0.46	GO:1900746	regulation of vascular endothelial growth factor signaling pathway
0.45	GO:1904951	positive regulation of establishment of protein localization
0.44	GO:1990830	cellular response to leukemia inhibitory factor
0.44	GO:0007219	Notch signaling pathway
0.38	GO:1903506	regulation of nucleic acid-templated transcription
0.38	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.77	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.45	GO:0004725	protein tyrosine phosphatase activity
0.32	GO:0005515	protein binding

0.41	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm
0.36	GO:0005886	plasma membrane
0.36	GO:0098562	cytoplasmic side of membrane
0.35	GO:0097708	intracellular vesicle
0.35	GO:0012505	endomembrane system
0.33	GO:0005819	spindle
0.30	GO:0016021	integral component of membrane

0.77

GO:0008138

tr|T1EM69|T1EM69_HELRO
Uncharacterized protein
Search

0.72	FUS-interacting serine-arginine-rich protein 1

0.72	GO:0043484	regulation of RNA splicing
0.53	GO:0050684	regulation of mRNA processing
0.50	GO:0006376	mRNA splice site selection
0.44	GO:0045292	mRNA cis splicing, via spliceosome
0.43	GO:1903312	negative regulation of mRNA metabolic process
0.43	GO:0016482	cytosolic transport
0.41	GO:0010629	negative regulation of gene expression
0.35	GO:0000244	spliceosomal tri-snRNP complex assembly
0.35	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.35	GO:0051028	mRNA transport

0.59	GO:0003723	RNA binding
0.36	GO:0050733	RS domain binding
0.35	GO:0051082	unfolded protein binding

0.43	GO:0016607	nuclear speck
0.40	GO:0005829	cytosol
0.34	GO:0043679	axon terminus
0.34	GO:0043025	neuronal cell body
0.34	GO:0030425	dendrite

tr|T1EM70|T1EM70_HELRO
Uncharacterized protein
Search

EIF2S3

0.83	Eukaryotic translation initiation factor 2 subunit

0.63	GO:0006413	translational initiation
0.36	GO:0045903	positive regulation of translational fidelity
0.35	GO:0002181	cytoplasmic translation
0.35	GO:0022618	ribonucleoprotein complex assembly
0.34	GO:0006414	translational elongation
0.34	GO:0034968	histone lysine methylation
0.32	GO:0055085	transmembrane transport
0.32	GO:0055114	oxidation-reduction process

0.67	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.63	GO:0003743	translation initiation factor activity
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0045296	cadherin binding
0.36	GO:0031369	translation initiation factor binding
0.34	GO:0003746	translation elongation factor activity
0.34	GO:0000049	tRNA binding

0.44	GO:0005850	eukaryotic translation initiation factor 2 complex
0.36	GO:0043614	multi-eIF complex
0.36	GO:0070062	extracellular exosome
0.35	GO:0016282	eukaryotic 43S preinitiation complex
0.35	GO:0033290	eukaryotic 48S preinitiation complex
0.34	GO:0005634	nucleus
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.34

EC:2.1.1.43

GO:0018024

tr|T1EM71|T1EM71_HELRO
Uncharacterized protein
Search

0.53	GO:0055114	oxidation-reduction process
0.39	GO:0019373	epoxygenase P450 pathway
0.37	GO:0043651	linoleic acid metabolic process
0.35	GO:0033574	response to testosterone
0.35	GO:0043390	aflatoxin B1 metabolic process
0.34	GO:0006805	xenobiotic metabolic process
0.33	GO:0044550	secondary metabolite biosynthetic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.65	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.37	GO:0019825	oxygen binding

0.36	GO:0044432	endoplasmic reticulum part
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0031984	organelle subcompartment
0.34	GO:0031090	organelle membrane
0.34	GO:0009986	cell surface
0.33	GO:0043233	organelle lumen
0.30	GO:0016021	integral component of membrane

0.68

EC:1.14

GO:0016705

tr|T1EM72|T1EM72_HELRO
Uncharacterized protein
Search

0.49	Serine protease inhibitor

0.49	GO:0010951	negative regulation of endopeptidase activity
0.41	GO:0006508	proteolysis
0.36	GO:2000266	regulation of blood coagulation, intrinsic pathway

0.51	GO:0004867	serine-type endopeptidase inhibitor activity
0.42	GO:0008233	peptidase activity
0.35	GO:0008201	heparin binding
0.32	GO:0016740	transferase activity

0.73	GO:0005615	extracellular space
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.42

GO:0008233

tr|T1EM73|T1EM73_HELRO
Uncharacterized protein
Search

PDCL3

0.71	Phosducin like 3

0.70	GO:2000059	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.67	GO:0001938	positive regulation of endothelial cell proliferation
0.66	GO:0045766	positive regulation of angiogenesis
0.65	GO:0050730	regulation of peptidyl-tyrosine phosphorylation
0.57	GO:0008616	queuosine biosynthetic process
0.56	GO:0006457	protein folding
0.39	GO:0055085	transmembrane transport
0.39	GO:0045454	cell redox homeostasis
0.38	GO:0007329	positive regulation of transcription from RNA polymerase II promoter by pheromones
0.38	GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process

0.69	GO:0043184	vascular endothelial growth factor receptor 2 binding
0.67	GO:0044183	protein binding involved in protein folding
0.61	GO:0008479	queuine tRNA-ribosyltransferase activity
0.37	GO:0031683	G-protein beta/gamma-subunit complex binding
0.37	GO:0008536	Ran GTPase binding
0.36	GO:0003779	actin binding
0.36	GO:0051287	NAD binding
0.34	GO:0022857	transmembrane transporter activity
0.33	GO:0003676	nucleic acid binding

0.55	GO:0005829	cytosol
0.51	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.61

EC:2.4.2.29

GO:0008479

tr|T1EM74|T1EM74_HELRO
Uncharacterized protein
Search

0.75	GO:0035335	peptidyl-tyrosine dephosphorylation
0.49	GO:1900121	negative regulation of receptor binding
0.49	GO:0031102	neuron projection regeneration
0.49	GO:0048679	regulation of axon regeneration
0.45	GO:0016477	cell migration
0.36	GO:0007155	cell adhesion
0.35	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway
0.35	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway
0.34	GO:0097374	sensory neuron axon guidance
0.34	GO:0050775	positive regulation of dendrite morphogenesis

0.75	GO:0004725	protein tyrosine phosphatase activity
0.51	GO:0035373	chondroitin sulfate proteoglycan binding
0.45	GO:0032403	protein complex binding
0.37	GO:0008201	heparin binding
0.36	GO:0019198	transmembrane receptor protein phosphatase activity
0.34	GO:0030971	receptor tyrosine kinase binding
0.34	GO:0042301	phosphate ion binding

0.47	GO:0043025	neuronal cell body
0.45	GO:0043005	neuron projection
0.35	GO:0070062	extracellular exosome
0.34	GO:0060076	excitatory synapse
0.34	GO:0030427	site of polarized growth
0.33	GO:0120038	plasma membrane bounded cell projection part
0.33	GO:0005768	endosome
0.33	GO:0005887	integral component of plasma membrane
0.33	GO:0043231	intracellular membrane-bounded organelle

0.75

EC:3.1.3.48

GO:0004725

tr|T1EM75|T1EM75_HELRO
Uncharacterized protein
Search

HSP90B1

0.90	Epididymis luminal protein 35

0.69	GO:0006457	protein folding
0.62	GO:0006950	response to stress
0.56	GO:0031247	actin rod assembly
0.55	GO:0071318	cellular response to ATP
0.53	GO:1903513	endoplasmic reticulum to cytosol transport
0.53	GO:0032527	protein exit from endoplasmic reticulum
0.51	GO:0036293	response to decreased oxygen levels
0.50	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.50	GO:0043666	regulation of phosphoprotein phosphatase activity
0.49	GO:0043066	negative regulation of apoptotic process

0.71	GO:0051082	unfolded protein binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0050750	low-density lipoprotein particle receptor binding
0.52	GO:0019903	protein phosphatase binding
0.42	GO:0003723	RNA binding
0.35	GO:0005509	calcium ion binding
0.34	GO:0019104	DNA N-glycosylase activity

0.53	GO:0005788	endoplasmic reticulum lumen
0.51	GO:0030496	midbody
0.50	GO:0048471	perinuclear region of cytoplasm
0.49	GO:0034663	endoplasmic reticulum chaperone complex
0.47	GO:0005789	endoplasmic reticulum membrane
0.46	GO:0005829	cytosol
0.42	GO:0042470	melanosome
0.38	GO:0005886	plasma membrane
0.36	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion

0.34

EC:3.2.2

GO:0019104

tr|T1EM76|T1EM76_HELRO
Protein-lysine N-methyltransferase HELRODRAFT_157178
Search

EEF1AKMT1

0.88	N(6)-adenine-specific DNA methyltransferase 2 (Fragment)

0.70

GO:0018022

peptidyl-lysine methylation

0.70	GO:0016279	protein-lysine N-methyltransferase activity
0.48	GO:0003676	nucleic acid binding
0.34	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity
0.32	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups

0.45	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.70

GO:0016279

tr|T1EM77|T1EM77_HELRO
Uracil-DNA glycosylase
Search

UNG

0.51	Uracil-DNA glycosylase

0.73	GO:0006284	base-excision repair
0.35	GO:0051052	regulation of DNA metabolic process
0.35	GO:0016446	somatic hypermutation of immunoglobulin genes
0.35	GO:0009223	pyrimidine deoxyribonucleotide catabolic process
0.35	GO:0045935	positive regulation of nucleobase-containing compound metabolic process
0.35	GO:0070734	histone H3-K27 methylation
0.35	GO:0016447	somatic recombination of immunoglobulin gene segments
0.35	GO:0002891	positive regulation of immunoglobulin mediated immune response
0.35	GO:0002639	positive regulation of immunoglobulin production
0.34	GO:0010604	positive regulation of macromolecule metabolic process

0.80	GO:0097506	deaminated base DNA N-glycosylase activity
0.35	GO:0003684	damaged DNA binding
0.35	GO:0008263	pyrimidine-specific mismatch base pair DNA N-glycosylase activity
0.34	GO:0043024	ribosomal small subunit binding
0.34	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity
0.33	GO:0008270	zinc ion binding

0.48	GO:0005737	cytoplasm
0.47	GO:0005634	nucleus
0.33	GO:0042025	host cell nucleus
0.33	GO:0043233	organelle lumen
0.32	GO:0044446	intracellular organelle part

0.34

EC:4.2.99.18

GO:0003906

tr|T1EM78|T1EM78_HELRO
Uncharacterized protein
Search

0.81	Kv channel-interacting protein 4

0.40	GO:0045163	clustering of voltage-gated potassium channels
0.40	GO:0097623	potassium ion export across plasma membrane
0.40	GO:0086009	membrane repolarization
0.39	GO:1901379	regulation of potassium ion transmembrane transport
0.37	GO:0065009	regulation of molecular function
0.35	GO:0005513	detection of calcium ion
0.34	GO:0086001	cardiac muscle cell action potential
0.34	GO:0061337	cardiac conduction
0.34	GO:0051291	protein heterooligomerization
0.34	GO:0006936	muscle contraction

0.64	GO:0005509	calcium ion binding
0.42	GO:0015459	potassium channel regulator activity
0.40	GO:0005250	A-type (transient outward) potassium channel activity
0.40	GO:0044325	ion channel binding
0.39	GO:0047485	protein N-terminus binding
0.36	GO:0042802	identical protein binding
0.35	GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization
0.34	GO:0046923	ER retention sequence binding
0.34	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.34	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding

0.39	GO:0008076	voltage-gated potassium channel complex
0.35	GO:0030425	dendrite
0.34	GO:0043679	axon terminus
0.34	GO:0030424	axon
0.34	GO:0005737	cytoplasm
0.33	GO:0032993	protein-DNA complex
0.33	GO:0005634	nucleus

tr|T1EM79|T1EM79_HELRO
Uncharacterized protein
Search

0.82	Putative host cell transcription factor hcfc1 (Fragment)

0.50	GO:0019045	latent virus replication
0.50	GO:0043982	histone H4-K8 acetylation
0.50	GO:0043981	histone H4-K5 acetylation
0.49	GO:0043984	histone H4-K16 acetylation
0.46	GO:0050821	protein stabilization
0.45	GO:0006366	transcription by RNA polymerase II
0.45	GO:0045944	positive regulation of transcription by RNA polymerase II
0.43	GO:0043254	regulation of protein complex assembly
0.37	GO:0000122	negative regulation of transcription by RNA polymerase II
0.36	GO:0071407	cellular response to organic cyclic compound

0.50	GO:0043996	histone acetyltransferase activity (H4-K8 specific)
0.50	GO:0046972	histone acetyltransferase activity (H4-K16 specific)
0.50	GO:0043995	histone acetyltransferase activity (H4-K5 specific)
0.49	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding
0.48	GO:0033613	activating transcription factor binding
0.47	GO:0045296	cadherin binding
0.46	GO:0003713	transcription coactivator activity
0.46	GO:0030674	protein binding, bridging
0.46	GO:0003682	chromatin binding
0.44	GO:0042802	identical protein binding

0.82	GO:0071339	MLL1 complex
0.81	GO:0048188	Set1C/COMPASS complex
0.48	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex
0.47	GO:0043025	neuronal cell body
0.46	GO:0070461	SAGA-type complex
0.37	GO:0030425	dendrite
0.37	GO:0030424	axon
0.36	GO:0005737	cytoplasm
0.34	GO:0044666	MLL3/4 complex
0.30	GO:0016020	membrane

tr|T1EM80|T1EM80_HELRO
Uncharacterized protein
Search

SLC13A5

0.63	Solute carrier family 13 member 5

0.73	GO:0006814	sodium ion transport
0.55	GO:0055085	transmembrane transport
0.47	GO:0015746	citrate transport
0.47	GO:0015744	succinate transport
0.33	GO:0007165	signal transduction
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression
0.33	GO:0006520	cellular amino acid metabolic process

0.56	GO:0005215	transporter activity
0.33	GO:0030170	pyridoxal phosphate binding
0.33	GO:0001104	RNA polymerase II transcription cofactor activity

0.41	GO:0005887	integral component of plasma membrane
0.34	GO:0070062	extracellular exosome
0.34	GO:0005634	nucleus
0.33	GO:0016323	basolateral plasma membrane
0.32	GO:0031974	membrane-enclosed lumen
0.32	GO:0043234	protein complex
0.32	GO:0044446	intracellular organelle part

tr|T1EM81|T1EM81_HELRO
Uncharacterized protein
Search

TRAPPC4

0.90	Trafficking protein particle complex subunit 4

0.69	GO:0016192	vesicle-mediated transport
0.52	GO:0016358	dendrite development
0.43	GO:0046907	intracellular transport
0.42	GO:0065009	regulation of molecular function
0.35	GO:0045212	neurotransmitter receptor biosynthetic process
0.34	GO:0051650	establishment of vesicle localization
0.34	GO:0016050	vesicle organization
0.34	GO:0042176	regulation of protein catabolic process
0.33	GO:0006461	protein complex assembly
0.33	GO:0061024	membrane organization

0.48	GO:0017112	Rab guanyl-nucleotide exchange factor activity
0.33	GO:0030234	enzyme regulator activity

0.82	GO:0030008	TRAPP complex
0.51	GO:0008021	synaptic vesicle
0.50	GO:0030425	dendrite
0.50	GO:0005795	Golgi stack
0.37	GO:0005783	endoplasmic reticulum
0.34	GO:0045211	postsynaptic membrane
0.34	GO:0030054	cell junction
0.34	GO:0000139	Golgi membrane
0.33	GO:0005829	cytosol
0.33	GO:1905369	endopeptidase complex

tr|T1EM82|T1EM82_HELRO
Uncharacterized protein
Search

0.50	GO:0006508	proteolysis
0.45	GO:0010020	chloroplast fission
0.44	GO:0009793	embryo development ending in seed dormancy
0.35	GO:0030163	protein catabolic process
0.34	GO:0051013	microtubule severing
0.34	GO:0043632	modification-dependent macromolecule catabolic process
0.34	GO:0051301	cell division
0.33	GO:0044267	cellular protein metabolic process

0.56	GO:0004222	metalloendopeptidase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0004176	ATP-dependent peptidase activity
0.34	GO:0008568	microtubule-severing ATPase activity
0.33	GO:0008270	zinc ion binding

0.43	GO:0009706	chloroplast inner membrane
0.35	GO:0005739	mitochondrion
0.34	GO:1905369	endopeptidase complex
0.33	GO:0043234	protein complex
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.56

GO:0004222

tr|T1EM83|T1EM83_HELRO
Uncharacterized protein
Search

RPL34

0.66	Large subunit ribosomal protein L34e

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.37	GO:0042254	ribosome biogenesis
0.33	GO:0006605	protein targeting

0.64	GO:0003735	structural constituent of ribosome
0.36	GO:0017022	myosin binding
0.35	GO:0003723	RNA binding

0.61	GO:0005840	ribosome
0.38	GO:0044445	cytosolic part
0.35	GO:0044446	intracellular organelle part
0.35	GO:0030687	preribosome, large subunit precursor
0.33	GO:0098805	whole membrane
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0019867	outer membrane
0.33	GO:0098796	membrane protein complex
0.32	GO:0005739	mitochondrion
0.32	GO:0031975	envelope

tr|T1EM84|T1EM84_HELRO
Palmitoyltransferase
Search

0.43	Palmitoyltransferase

0.56	GO:0018345	protein palmitoylation
0.53	GO:0018231	peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine
0.41	GO:0034613	cellular protein localization
0.34	GO:0006338	chromatin remodeling
0.33	GO:1903830	magnesium ion transmembrane transport
0.32	GO:0055114	oxidation-reduction process

0.80	GO:0019706	protein-cysteine S-palmitoyltransferase activity
0.34	GO:0015095	magnesium ion transmembrane transporter activity
0.33	GO:0005515	protein binding
0.32	GO:0003677	DNA binding
0.32	GO:0016491	oxidoreductase activity

0.51	GO:0002178	palmitoyltransferase complex
0.49	GO:0031228	intrinsic component of Golgi membrane
0.45	GO:0005783	endoplasmic reticulum
0.44	GO:0005829	cytosol
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0071565	nBAF complex
0.34	GO:0016514	SWI/SNF complex
0.30	GO:0016021	integral component of membrane

0.80

EC:2.3.1.225

GO:0019706

tr|T1EM85|T1EM85_HELRO
Uncharacterized protein
Search

GALC

0.90	galactocerebrosidase precursor

0.86	GO:0006683	galactosylceramide catabolic process
0.34	GO:0045859	regulation of protein kinase activity

0.86	GO:0004336	galactosylceramidase activity
0.34	GO:0019887	protein kinase regulator activity

0.46	GO:0005764	lysosome
0.42	GO:0005739	mitochondrion
0.37	GO:0070062	extracellular exosome
0.35	GO:0005775	vacuolar lumen
0.34	GO:0005956	protein kinase CK2 complex
0.30	GO:0031224	intrinsic component of membrane

0.86

EC:3.2.1.46

GO:0004336

tr|T1EM86|T1EM86_HELRO
Uncharacterized protein
Search

SYNJ1

0.83	Phosphatidylinositol-bisphosphatase

0.83	GO:0048488	synaptic vesicle endocytosis
0.81	GO:0046856	phosphatidylinositol dephosphorylation
0.39	GO:1904980	positive regulation of endosome organization
0.38	GO:0072318	clathrin coat disassembly
0.37	GO:0014015	positive regulation of gliogenesis
0.37	GO:0016082	synaptic vesicle priming
0.37	GO:0048260	positive regulation of receptor-mediated endocytosis
0.37	GO:0032526	response to retinoic acid
0.37	GO:0098884	postsynaptic neurotransmitter receptor internalization
0.37	GO:0007612	learning

0.83	GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity
0.54	GO:0003723	RNA binding
0.38	GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity
0.38	GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity
0.37	GO:0004438	phosphatidylinositol-3-phosphatase activity
0.37	GO:0008022	protein C-terminus binding
0.37	GO:0017124	SH3 domain binding
0.36	GO:0032403	protein complex binding
0.35	GO:0052659	inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity
0.35	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity

0.72	GO:0045202	synapse
0.39	GO:0030132	clathrin coat of coated pit
0.39	GO:0043005	neuron projection
0.38	GO:0098590	plasma membrane region
0.37	GO:0005874	microtubule
0.37	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0012506	vesicle membrane
0.37	GO:0120038	plasma membrane bounded cell projection part
0.35	GO:0044754	autolysosome
0.33	GO:0005829	cytosol

0.37	EC:3.1.3.64	GO:0004438
0.35	KEGG:R03430	GO:0052659

tr|T1EM87|T1EM87_HELRO
Small ubiquitin-related modifier
Search

0.76	Small ubiquitin-related modifier

0.80	GO:0016925	protein sumoylation
0.41	GO:1903052	positive regulation of proteolysis involved in cellular protein catabolic process
0.41	GO:0043392	negative regulation of DNA binding
0.41	GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process
0.38	GO:0060216	definitive hemopoiesis
0.37	GO:0043009	chordate embryonic development
0.37	GO:1903322	positive regulation of protein modification by small protein conjugation or removal
0.36	GO:0070911	global genome nucleotide-excision repair
0.36	GO:2000058	regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.35	GO:0045944	positive regulation of transcription by RNA polymerase II

0.49	GO:0031386	protein tag
0.42	GO:0001222	transcription corepressor binding
0.42	GO:0019899	enzyme binding
0.38	GO:0019789	SUMO transferase activity
0.35	GO:0046965	retinoid X receptor binding
0.33	GO:0003723	RNA binding

0.60	GO:0005634	nucleus
0.41	GO:0031974	membrane-enclosed lumen
0.38	GO:0044446	intracellular organelle part
0.35	GO:0070062	extracellular exosome
0.34	GO:0005737	cytoplasm
0.33	GO:0005694	chromosome
0.32	GO:0043234	protein complex

tr|T1EM88|T1EM88_HELRO
Uncharacterized protein
Search

RPL17

0.70	Large subunit ribosomal protein L17e

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process

0.64

GO:0003735

structural constituent of ribosome

0.71	GO:0015934	large ribosomal subunit
0.33	GO:0005856	cytoskeleton
0.30	GO:0031224	intrinsic component of membrane

tr|T1EM89|T1EM89_HELRO
Uncharacterized protein
Search

PBLD

0.70	Phenazine biosynthesis like protein domain containing

0.53	GO:0060392	negative regulation of SMAD protein import into nucleus
0.52	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation
0.51	GO:0030277	maintenance of gastrointestinal epithelium
0.51	GO:0010719	negative regulation of epithelial to mesenchymal transition
0.50	GO:0010633	negative regulation of epithelial cell migration
0.50	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.50	GO:0050680	negative regulation of epithelial cell proliferation
0.49	GO:0009058	biosynthetic process
0.34	GO:0003407	neural retina development
0.32	GO:2001141	regulation of RNA biosynthetic process

0.46	GO:0042802	identical protein binding
0.43	GO:0016853	isomerase activity
0.33	GO:0008080	N-acetyltransferase activity
0.33	GO:0046983	protein dimerization activity

0.37	GO:0005737	cytoplasm
0.34	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.43

EC:5

GO:0016853

tr|T1EM90|T1EM90_HELRO
Uncharacterized protein
Search

PPP1R2

0.90	Phosphatase inhibitor

0.83	GO:0032515	negative regulation of phosphoprotein phosphatase activity
0.70	GO:0009966	regulation of signal transduction
0.39	GO:0005977	glycogen metabolic process
0.37	GO:0010824	regulation of centrosome duplication
0.36	GO:0007098	centrosome cycle
0.36	GO:0051304	chromosome separation
0.35	GO:0051301	cell division
0.35	GO:0032091	negative regulation of protein binding
0.34	GO:0007568	aging
0.34	GO:0006869	lipid transport

0.83	GO:0004864	protein phosphatase inhibitor activity
0.35	GO:0005515	protein binding
0.35	GO:0031409	pigment binding
0.33	GO:0008289	lipid binding
0.33	GO:0004721	phosphoprotein phosphatase activity

0.50	GO:0000164	protein phosphatase type 1 complex
0.35	GO:0098723	skeletal muscle myofibril
0.35	GO:0043197	dendritic spine
0.35	GO:0030426	growth cone
0.30	GO:0016020	membrane

0.33

GO:0004721

tr|T1EM91|T1EM91_HELRO
Uncharacterized protein
Search

0.63	GO:0032259	methylation
0.37	GO:0008213	protein alkylation
0.35	GO:0000154	rRNA modification
0.35	GO:0043547	positive regulation of GTPase activity
0.34	GO:0007165	signal transduction

0.63	GO:0008168	methyltransferase activity
0.45	GO:0003676	nucleic acid binding
0.36	GO:0140102	catalytic activity, acting on a rRNA
0.35	GO:0005096	GTPase activator activity
0.34	GO:0140096	catalytic activity, acting on a protein

0.39

GO:0005840

ribosome

0.63

GO:0008168

tr|T1EM92|T1EM92_HELRO
Uncharacterized protein
Search

0.63	Neurohemerythrin

0.40	GO:0015671	oxygen transport
0.34	GO:0046686	response to cadmium ion
0.32	GO:0007165	signal transduction

0.63	GO:0005506	iron ion binding
0.40	GO:0005344	oxygen carrier activity
0.32	GO:0004871	signal transducer activity

0.32	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

tr|T1EM93|T1EM93_HELRO
Uncharacterized protein
Search

0.11	WD40 domain-containing protein

0.73	GO:0007035	vacuolar acidification
0.71	GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly
0.41	GO:1901546	regulation of synaptic vesicle lumen acidification
0.40	GO:0001755	neural crest cell migration
0.39	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.39	GO:0030100	regulation of endocytosis
0.36	GO:0007018	microtubule-based movement

0.69	GO:0017137	Rab GTPase binding
0.36	GO:0003777	microtubule motor activity
0.34	GO:0030554	adenyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.76	GO:0043291	RAVE complex
0.70	GO:0008021	synaptic vesicle
0.43	GO:0099501	exocytic vesicle membrane
0.40	GO:0030054	cell junction
0.40	GO:0005615	extracellular space
0.37	GO:0030286	dynein complex

tr|T1EM94|T1EM94_HELRO
Uncharacterized protein
Search

0.47	Heparan SulphoTransferase

0.45	GO:0016348	imaginal disc-derived leg joint morphogenesis
0.45	GO:0051036	regulation of endosome size
0.44	GO:0008407	chaeta morphogenesis
0.44	GO:0048190	wing disc dorsal/ventral pattern formation
0.44	GO:0008586	imaginal disc-derived wing vein morphogenesis
0.44	GO:0007474	imaginal disc-derived wing vein specification
0.44	GO:0008587	imaginal disc-derived wing margin morphogenesis
0.43	GO:0007032	endosome organization
0.43	GO:0001745	compound eye morphogenesis
0.43	GO:0007040	lysosome organization

0.78

GO:0008146

sulfotransferase activity

0.37	GO:0031932	TORC2 complex
0.34	GO:0005796	Golgi lumen
0.30	GO:0016020	membrane

0.78

EC:2.8.2

GO:0008146

tr|T1EM95|T1EM95_HELRO
Uncharacterized protein
Search

0.79

Calpain-B

0.61	GO:0006508	proteolysis
0.45	GO:0007586	digestion
0.38	GO:0048468	cell development
0.37	GO:0031032	actomyosin structure organization
0.37	GO:0010927	cellular component assembly involved in morphogenesis
0.37	GO:0051146	striated muscle cell differentiation
0.36	GO:0097435	supramolecular fiber organization
0.36	GO:0010631	epithelial cell migration
0.36	GO:0070925	organelle assembly
0.36	GO:0071695	anatomical structure maturation

0.82	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.64	GO:0005509	calcium ion binding

0.45	GO:0005622	intracellular
0.30	GO:0016020	membrane

tr|T1EM96|T1EM96_HELRO
Uncharacterized protein
Search

0.53	Serine protease snake

0.68	GO:0031639	plasminogen activation
0.47	GO:0014909	smooth muscle cell migration
0.45	GO:0048008	platelet-derived growth factor receptor signaling pathway
0.44	GO:0001666	response to hypoxia
0.42	GO:0045861	negative regulation of proteolysis
0.39	GO:0032501	multicellular organismal process
0.38	GO:0019953	sexual reproduction
0.38	GO:0007599	hemostasis
0.38	GO:0042060	wound healing
0.35	GO:0032101	regulation of response to external stimulus

0.69	GO:0004252	serine-type endopeptidase activity
0.44	GO:0051219	phosphoprotein binding
0.41	GO:0005102	receptor binding
0.37	GO:0005509	calcium ion binding
0.33	GO:0004040	amidase activity
0.33	GO:0005044	scavenger receptor activity
0.33	GO:0016758	transferase activity, transferring hexosyl groups
0.32	GO:0016301	kinase activity

0.55	GO:0005576	extracellular region
0.45	GO:0030141	secretory granule
0.44	GO:0045177	apical part of cell
0.42	GO:0009986	cell surface
0.35	GO:0097223	sperm part
0.35	GO:0097180	serine protease inhibitor complex
0.34	GO:1905286	serine-type peptidase complex
0.34	GO:0046658	anchored component of plasma membrane
0.34	GO:0005791	rough endoplasmic reticulum
0.33	GO:0019897	extrinsic component of plasma membrane

0.69

GO:0004252

tr|T1EM97|T1EM97_HELRO
Structural maintenance of chromosomes protein
Search

tr|T1EM98|T1EM98_HELRO
U3 small nucleolar RNA-associated protein 11
Search

UTP11

0.71	U3 small nucleolar RNA-associated protein 11

0.68	GO:0006364	rRNA processing
0.49	GO:0043065	positive regulation of apoptotic process
0.48	GO:0007399	nervous system development
0.45	GO:0042274	ribosomal small subunit biogenesis
0.38	GO:0034471	ncRNA 5'-end processing
0.36	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.35	GO:0043043	peptide biosynthetic process
0.34	GO:0044267	cellular protein metabolic process
0.34	GO:0009059	macromolecule biosynthetic process
0.33	GO:0009561	megagametogenesis

0.33	GO:0070006	metalloaminopeptidase activity
0.33	GO:0005515	protein binding
0.32	GO:0003723	RNA binding
0.32	GO:0046872	metal ion binding

0.79	GO:0032040	small-subunit processome
0.69	GO:0005730	nucleolus
0.47	GO:0005615	extracellular space
0.42	GO:0019013	viral nucleocapsid
0.38	GO:0005737	cytoplasm
0.33	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1EM99|T1EM99_HELRO
Glycogen [starch] synthase
Search

0.41	Glycogen [starch] synthase

0.77	GO:0005978	glycogen biosynthetic process
0.39	GO:0006310	DNA recombination

0.80	GO:0004373	glycogen (starch) synthase activity
0.40	GO:0008026	ATP-dependent helicase activity
0.36	GO:0030554	adenyl nucleotide binding
0.36	GO:0097367	carbohydrate derivative binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0003676	nucleic acid binding

0.80

EC:2.4.1.11

GO:0004373

tr|T1EMA0|T1EMA0_HELRO
Uncharacterized protein
Search

0.58	Solute carrier family 12 member 1

0.65	GO:1902476	chloride transmembrane transport
0.38	GO:0070634	transepithelial ammonium transport
0.38	GO:0030321	transepithelial chloride transport
0.38	GO:0046080	dUTP metabolic process
0.37	GO:0072488	ammonium transmembrane transport
0.35	GO:0005975	carbohydrate metabolic process

0.71	GO:0015377	cation:chloride symporter activity
0.38	GO:0004170	dUTP diphosphatase activity
0.37	GO:0008519	ammonium transmembrane transporter activity
0.36	GO:0019901	protein kinase binding
0.36	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.38	GO:0070062	extracellular exosome
0.34	GO:0016324	apical plasma membrane
0.30	GO:0016021	integral component of membrane

0.38	EC:3.6.1.23	GO:0004170
0.38	KEGG:R02100	GO:0004170

tr|T1EMA1|T1EMA1_HELRO
Uncharacterized protein
Search

RHOU

0.82	cell division control protein 42 homolog

0.77	GO:0007264	small GTPase mediated signal transduction
0.53	GO:1903955	positive regulation of protein targeting to mitochondrion
0.47	GO:0007010	cytoskeleton organization
0.46	GO:0008360	regulation of cell shape
0.45	GO:0000082	G1/S transition of mitotic cell cycle
0.42	GO:0030029	actin filament-based process
0.37	GO:0036302	atrioventricular canal development
0.37	GO:0071896	protein localization to adherens junction
0.37	GO:0055113	epiboly involved in gastrulation with mouth forming second
0.35	GO:0030155	regulation of cell adhesion

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0046872	metal ion binding
0.33	GO:0003796	lysozyme activity
0.33	GO:0005515	protein binding
0.33	GO:0003700	DNA binding transcription factor activity

0.45	GO:0005622	intracellular
0.37	GO:0005925	focal adhesion
0.36	GO:0098588	bounding membrane of organelle
0.35	GO:0042995	cell projection
0.35	GO:0012505	endomembrane system
0.34	GO:0043234	protein complex
0.34	GO:0043228	non-membrane-bounded organelle
0.34	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:3.2.1.17

GO:0003796

tr|T1EMA2|T1EMA2_HELRO
Uncharacterized protein
Search

RPS18

0.60	Ribosomal protein S18

0.58	GO:0043043	peptide biosynthetic process
0.54	GO:0044267	cellular protein metabolic process
0.52	GO:0010467	gene expression
0.51	GO:0009059	macromolecule biosynthetic process
0.41	GO:0051726	regulation of cell cycle
0.39	GO:0042254	ribosome biogenesis
0.35	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.34	GO:0007275	multicellular organism development

0.62	GO:0003735	structural constituent of ribosome
0.57	GO:0003723	RNA binding
0.35	GO:0005515	protein binding

0.59	GO:0005840	ribosome
0.42	GO:0005829	cytosol
0.39	GO:0044446	intracellular organelle part
0.36	GO:0031012	extracellular matrix
0.36	GO:0005634	nucleus
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.35	GO:0005791	rough endoplasmic reticulum
0.34	GO:0098562	cytoplasmic side of membrane
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network

tr|T1EMA3|T1EMA3_HELRO
Histone H2A
Search

tr|T1EMA4|T1EMA4_HELRO
Uncharacterized protein
Search

0.75	Protein kinase C beta type

0.63	GO:0006468	protein phosphorylation
0.60	GO:0035556	intracellular signal transduction
0.51	GO:0050861	positive regulation of B cell receptor signaling pathway
0.51	GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway
0.51	GO:0050853	B cell receptor signaling pathway
0.50	GO:0010829	negative regulation of glucose transport
0.50	GO:0018210	peptidyl-threonine modification
0.49	GO:0042113	B cell activation
0.49	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.49	GO:0071322	cellular response to carbohydrate stimulus

0.81	GO:0004697	protein kinase C activity
0.59	GO:0008270	zinc ion binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0035403	histone kinase activity (H3-T6 specific)
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.52	GO:0050681	androgen receptor binding
0.51	GO:0005080	protein kinase C binding
0.50	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity

0.44	GO:0005654	nucleoplasm
0.44	GO:0005829	cytosol
0.40	GO:0005886	plasma membrane
0.36	GO:0000935	division septum
0.35	GO:0120038	plasma membrane bounded cell projection part
0.35	GO:0070062	extracellular exosome
0.35	GO:0014069	postsynaptic density
0.35	GO:0097447	dendritic tree
0.34	GO:0005911	cell-cell junction
0.34	GO:0005903	brush border

0.81

EC:2.7.11.13

GO:0004697

tr|T1EMA5|T1EMA5_HELRO
Uncharacterized protein
Search

0.45	Serine proteinase

0.61	GO:0006508	proteolysis
0.41	GO:0002542	Factor XII activation
0.41	GO:0051919	positive regulation of fibrinolysis
0.41	GO:0010756	positive regulation of plasminogen activation
0.40	GO:0007596	blood coagulation
0.40	GO:0030194	positive regulation of blood coagulation
0.40	GO:0051604	protein maturation
0.40	GO:0006898	receptor-mediated endocytosis
0.39	GO:0051788	response to misfolded protein
0.35	GO:0003050	regulation of systemic arterial blood pressure by atrial natriuretic peptide

0.69	GO:0004252	serine-type endopeptidase activity
0.42	GO:0005044	scavenger receptor activity
0.41	GO:0005509	calcium ion binding
0.35	GO:0017080	sodium channel regulator activity
0.33	GO:0051787	misfolded protein binding
0.33	GO:0070008	serine-type exopeptidase activity
0.32	GO:0005216	ion channel activity
0.32	GO:0003779	actin binding
0.32	GO:0001871	pattern binding
0.32	GO:0016301	kinase activity

0.42	GO:0005576	extracellular region
0.35	GO:0031226	intrinsic component of plasma membrane
0.35	GO:0005737	cytoplasm
0.34	GO:0043025	neuronal cell body
0.34	GO:0016604	nuclear body
0.34	GO:0009986	cell surface
0.34	GO:0015629	actin cytoskeleton
0.34	GO:0012505	endomembrane system
0.33	GO:0031982	vesicle
0.33	GO:0031984	organelle subcompartment

0.69

GO:0004252

tr|T1EMA6|T1EMA6_HELRO
Uncharacterized protein
Search

PIGM

0.65	Phosphatidylinositol glycan anchor biosynthesis, class M

0.78	GO:0006506	GPI anchor biosynthetic process
0.46	GO:0031505	fungal-type cell wall organization
0.45	GO:0097502	mannosylation
0.42	GO:0017183	peptidyl-diphthamide biosynthetic process from peptidyl-histidine
0.38	GO:0032259	methylation
0.33	GO:0036065	fucosylation
0.32	GO:0006486	protein glycosylation
0.32	GO:0006518	peptide metabolic process
0.32	GO:0043604	amide biosynthetic process
0.32	GO:0010467	gene expression

0.69	GO:0016758	transferase activity, transferring hexosyl groups
0.43	GO:0004164	diphthine synthase activity
0.35	GO:0046982	protein heterodimerization activity
0.32	GO:0003735	structural constituent of ribosome
0.32	GO:1901265	nucleoside phosphate binding
0.32	GO:0036094	small molecule binding

0.49	GO:1990529	glycosylphosphatidylinositol-mannosyltransferase I complex
0.40	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0032580	Golgi cisterna membrane
0.32	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.69

EC:2.4.1

GO:0016758

tr|T1EMA7|T1EMA7_HELRO
Uncharacterized protein
Search

0.83	Ezrin-moesin-radixin

0.39	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity
0.35	GO:0016336	establishment or maintenance of polarity of larval imaginal disc epithelium
0.35	GO:0045313	rhabdomere membrane biogenesis
0.35	GO:0016057	regulation of membrane potential in photoreceptor cell
0.35	GO:0110028	positive regulation of mitotic spindle organization
0.35	GO:0007318	pole plasm protein localization
0.35	GO:0045433	male courtship behavior, veined wing generated song production
0.35	GO:0072499	photoreceptor cell axon guidance
0.35	GO:0035149	lumen formation, open tracheal system
0.35	GO:0032888	regulation of mitotic spindle elongation

0.72	GO:0003779	actin binding
0.34	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.34	GO:0008017	microtubule binding
0.33	GO:0005096	GTPase activator activity
0.32	GO:0046872	metal ion binding

0.69	GO:0005856	cytoskeleton
0.38	GO:0005912	adherens junction
0.35	GO:0035003	subapical complex
0.35	GO:0045169	fusome
0.35	GO:0005703	polytene chromosome puff
0.34	GO:0032154	cleavage furrow
0.34	GO:0035327	transcriptionally active chromatin
0.34	GO:0016324	apical plasma membrane
0.34	GO:0005938	cell cortex
0.33	GO:0099512	supramolecular fiber

tr|T1EMA8|T1EMA8_HELRO
Vesicle transport protein
Search

0.70	Vesicle transport protein (Fragment)

0.69	GO:0016192	vesicle-mediated transport
0.65	GO:0015031	protein transport
0.36	GO:0006850	mitochondrial pyruvate transmembrane transport
0.33	GO:0006468	protein phosphorylation

0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.36	GO:0070062	extracellular exosome
0.33	GO:0031966	mitochondrial membrane
0.33	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1EMA9|T1EMA9_HELRO
Uncharacterized protein
Search

LARS

0.60	Leucyl-tRNA synthetase b

0.78	GO:0006429	leucyl-tRNA aminoacylation
0.73	GO:0106074	aminoacyl-tRNA metabolism involved in translational fidelity
0.54	GO:1990253	cellular response to leucine starvation
0.54	GO:0071233	cellular response to leucine
0.53	GO:0006622	protein targeting to lysosome
0.51	GO:1904263	positive regulation of TORC1 signaling
0.50	GO:0008361	regulation of cell size
0.50	GO:0006425	glutaminyl-tRNA aminoacylation
0.48	GO:0043547	positive regulation of GTPase activity
0.47	GO:0010507	negative regulation of autophagy

0.79	GO:0004823	leucine-tRNA ligase activity
0.73	GO:0002161	aminoacyl-tRNA editing activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0004819	glutamine-tRNA ligase activity
0.48	GO:0005096	GTPase activator activity
0.43	GO:0004832	valine-tRNA ligase activity
0.34	GO:0005515	protein binding
0.33	GO:0004252	serine-type endopeptidase activity

0.53	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex
0.49	GO:0005764	lysosome
0.48	GO:0016604	nuclear body
0.46	GO:0005829	cytosol
0.46	GO:0005783	endoplasmic reticulum
0.30	GO:0031224	intrinsic component of membrane

0.79	EC:6.1.1.4	GO:0004823
0.79	KEGG:R03657	GO:0004823

tr|T1EMB0|T1EMB0_HELRO
Vacuolar protein sorting-associated protein 29
Search

VPS29

0.72	Vacuolar protein sorting-associated protein 29

0.81	GO:0042147	retrograde transport, endosome to Golgi
0.63	GO:0015031	protein transport
0.42	GO:0034613	cellular protein localization
0.39	GO:1990126	retrograde transport, endosome to plasma membrane
0.36	GO:0007034	vacuolar transport
0.36	GO:0001881	receptor recycling
0.34	GO:0006892	post-Golgi vesicle-mediated transport
0.34	GO:0016055	Wnt signaling pathway
0.34	GO:0010506	regulation of autophagy

0.42	GO:0008565	protein transporter activity
0.40	GO:0008270	zinc ion binding
0.34	GO:0005515	protein binding
0.32	GO:0016787	hydrolase activity

0.82	GO:0030904	retromer complex
0.68	GO:0005829	cytosol
0.45	GO:0005768	endosome
0.39	GO:0044433	cytoplasmic vesicle part
0.39	GO:0098805	whole membrane
0.39	GO:0043231	intracellular membrane-bounded organelle
0.38	GO:0098588	bounding membrane of organelle
0.34	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016787

tr|T1EMB1|T1EMB1_HELRO
Uncharacterized protein
Search

0.66	Inward rectifier potassium channel

0.78	GO:0034765	regulation of ion transmembrane transport
0.71	GO:0006813	potassium ion transport
0.61	GO:0098655	cation transmembrane transport
0.47	GO:0090099	negative regulation of decapentaplegic signaling pathway
0.45	GO:0035220	wing disc development
0.44	GO:0042391	regulation of membrane potential
0.36	GO:0045475	locomotor rhythm
0.36	GO:0098660	inorganic ion transmembrane transport
0.35	GO:0046662	regulation of oviposition
0.34	GO:0051876	pigment granule dispersal

0.84	GO:0005242	inward rectifier potassium channel activity
0.33	GO:0004672	protein kinase activity
0.33	GO:0046872	metal ion binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003676	nucleic acid binding

0.37	GO:0005887	integral component of plasma membrane
0.34	GO:0043025	neuronal cell body
0.34	GO:0043005	neuron projection
0.31	GO:0005622	intracellular

tr|T1EMB2|T1EMB2_HELRO
Uncharacterized protein
Search

RPL9

0.71	Ribosomal protein L9

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.39	GO:0008340	determination of adult lifespan
0.35	GO:1990090	cellular response to nerve growth factor stimulus
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0031047	gene silencing by RNA
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.33	GO:0019083	viral transcription

0.66	GO:0019843	rRNA binding
0.64	GO:0003735	structural constituent of ribosome
0.33	GO:0005515	protein binding

0.61	GO:0005840	ribosome
0.46	GO:0044445	cytosolic part
0.40	GO:0044446	intracellular organelle part
0.36	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion
0.34	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|T1EMB3|T1EMB3_HELRO
Uncharacterized protein
Search

NAPA

0.84	N-ethylmaleimide-sensitive factor attachment protein, alpha b

0.69	GO:0006886	intracellular protein transport
0.56	GO:0035494	SNARE complex disassembly
0.53	GO:0010807	regulation of synaptic vesicle priming
0.51	GO:0035249	synaptic transmission, glutamatergic
0.51	GO:0045176	apical protein localization
0.48	GO:0007420	brain development
0.47	GO:0030182	neuron differentiation
0.43	GO:0061025	membrane fusion
0.41	GO:0045494	photoreceptor cell maintenance
0.38	GO:0032781	positive regulation of ATPase activity

0.53	GO:0019905	syntaxin binding
0.50	GO:0005483	soluble NSF attachment protein activity
0.37	GO:0032403	protein complex binding
0.34	GO:0004435	phosphatidylinositol phospholipase C activity
0.33	GO:0005509	calcium ion binding
0.32	GO:0004871	signal transducer activity
0.32	GO:0003677	DNA binding

0.53	GO:0031201	SNARE complex
0.49	GO:0043209	myelin sheath
0.45	GO:0005774	vacuolar membrane
0.38	GO:0043195	terminal bouton
0.35	GO:0070062	extracellular exosome
0.34	GO:0005886	plasma membrane
0.33	GO:0000139	Golgi membrane
0.33	GO:0005634	nucleus
0.33	GO:0005829	cytosol

0.34	EC:3.1.4.11	GO:0004435
0.34	KEGG:R03435	GO:0004435

tr|T1EMB4|T1EMB4_HELRO
Phosphomannomutase
Search

PMM2

0.55	Phosphomannomutase

0.81	GO:0009298	GDP-mannose biosynthetic process
0.46	GO:0006013	mannose metabolic process
0.46	GO:0006487	protein N-linked glycosylation
0.44	GO:0045047	protein targeting to ER
0.36	GO:0019853	L-ascorbic acid biosynthetic process
0.35	GO:0009651	response to salt stress
0.33	GO:0007264	small GTPase mediated signal transduction
0.33	GO:0007186	G-protein coupled receptor signaling pathway

0.82	GO:0004615	phosphomannomutase activity
0.34	GO:0005515	protein binding
0.33	GO:0044877	macromolecular complex binding
0.33	GO:0003924	GTPase activity
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0019001	guanyl nucleotide binding
0.32	GO:0004871	signal transducer activity
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.49	GO:0043025	neuronal cell body
0.49	GO:0005737	cytoplasm
0.43	GO:0005634	nucleus
0.36	GO:0070062	extracellular exosome

0.82	EC:5.4.2.8	GO:0004615
0.82	KEGG:R01818	GO:0004615

tr|T1EMB5|T1EMB5_HELRO
Uncharacterized protein
Search

PP2B-14D

0.38	Serine/threonine-protein phosphatase

0.62	GO:0006470	protein dephosphorylation
0.40	GO:0034608	vulval location
0.40	GO:0034606	response to hermaphrodite contact
0.39	GO:0040010	positive regulation of growth rate
0.39	GO:0043052	thermotaxis
0.39	GO:0040040	thermosensory behavior
0.39	GO:0097499	protein localization to non-motile cilium
0.39	GO:0008355	olfactory learning
0.39	GO:0040024	dauer larval development
0.39	GO:0010446	response to alkaline pH

0.63	GO:0004721	phosphoprotein phosphatase activity
0.36	GO:0005509	calcium ion binding
0.35	GO:0005515	protein binding

0.38	GO:0043204	perikaryon
0.38	GO:0097730	non-motile cilium
0.38	GO:0030425	dendrite
0.37	GO:0030424	axon
0.35	GO:0005634	nucleus
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.63

GO:0004721

tr|T1EMB6|T1EMB6_HELRO
Uncharacterized protein
Search

0.10	Serine/threonine-protein kinase Nek3

0.63	GO:0006468	protein phosphorylation
0.44	GO:0007059	chromosome segregation
0.39	GO:0007346	regulation of mitotic cell cycle
0.38	GO:0044772	mitotic cell cycle phase transition
0.37	GO:0000077	DNA damage checkpoint
0.37	GO:1901987	regulation of cell cycle phase transition
0.37	GO:0031098	stress-activated protein kinase signaling cascade
0.37	GO:0016570	histone modification
0.37	GO:0032147	activation of protein kinase activity
0.35	GO:0036065	fucosylation

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0005509	calcium ion binding
0.35	GO:0008107	galactoside 2-alpha-L-fucosyltransferase activity

0.36	GO:0005730	nucleolus
0.36	GO:0005654	nucleoplasm
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.35

EC:2.4.1.69

GO:0008107

tr|T1EMB7|T1EMB7_HELRO
Uncharacterized protein
Search

0.46	Myosin heavy chain, muscle (Fragment)

0.67	GO:0007018	microtubule-based movement
0.32	GO:0055114	oxidation-reduction process

0.73	GO:0003774	motor activity
0.68	GO:0008017	microtubule binding
0.68	GO:0003779	actin binding
0.64	GO:0032403	protein complex binding
0.51	GO:0030554	adenyl nucleotide binding
0.51	GO:0032553	ribonucleotide binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.33	GO:0005198	structural molecule activity

0.77

GO:0016459

myosin complex

0.35

GO:0032440

tr|T1EMB8|T1EMB8_HELRO
Uncharacterized protein
Search

SLC18A3

0.42	Vesicular acetylcholine transporter-A

0.61	GO:0006855	drug transmembrane transport
0.45	GO:1901374	acetate ester transport
0.41	GO:0072488	ammonium transmembrane transport
0.41	GO:0015695	organic cation transport
0.41	GO:0006836	neurotransmitter transport
0.36	GO:0043051	regulation of pharyngeal pumping
0.36	GO:0007268	chemical synaptic transmission
0.36	GO:0046928	regulation of neurotransmitter secretion
0.36	GO:0002119	nematode larval development
0.35	GO:0006937	regulation of muscle contraction

0.61	GO:0015238	drug transmembrane transporter activity
0.46	GO:1901375	acetate ester transmembrane transporter activity
0.46	GO:0016746	transferase activity, transferring acyl groups
0.45	GO:0042166	acetylcholine binding
0.42	GO:0015101	organic cation transmembrane transporter activity
0.42	GO:0005326	neurotransmitter transporter activity
0.41	GO:0008519	ammonium transmembrane transporter activity
0.35	GO:0008504	monoamine transmembrane transporter activity
0.33	GO:0008237	metallopeptidase activity
0.33	GO:0005515	protein binding

0.44	GO:0030121	AP-1 adaptor complex
0.44	GO:0030122	AP-2 adaptor complex
0.39	GO:0060200	clathrin-sculpted acetylcholine transport vesicle
0.39	GO:0005887	integral component of plasma membrane
0.38	GO:0098793	presynapse
0.37	GO:0043005	neuron projection
0.36	GO:0070382	exocytic vesicle
0.36	GO:0060076	excitatory synapse
0.35	GO:0120038	plasma membrane bounded cell projection part
0.34	GO:0031301	integral component of organelle membrane

0.46

EC:2.3

GO:0016746

tr|T1EMB9|T1EMB9_HELRO
Uncharacterized protein
Search

0.10	Putative RNA helicase

0.37	GO:0010501	RNA secondary structure unwinding
0.36	GO:0007059	chromosome segregation
0.36	GO:0006413	translational initiation
0.34	GO:0007420	brain development
0.34	GO:0010468	regulation of gene expression
0.33	GO:0015074	DNA integration

0.66	GO:0004386	helicase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0003676	nucleic acid binding
0.36	GO:0008186	RNA-dependent ATPase activity
0.34	GO:0140098	catalytic activity, acting on RNA
0.33	GO:0003735	structural constituent of ribosome

0.36	GO:0036464	cytoplasmic ribonucleoprotein granule
0.36	GO:0005730	nucleolus
0.33	GO:0015934	large ribosomal subunit
0.30	GO:0031224	intrinsic component of membrane

tr|T1EMC0|T1EMC0_HELRO
Uncharacterized protein
Search

SEC13

0.97	SEC13 homolog, nuclear pore and COPII coat complex component

0.84	GO:1904263	positive regulation of TORC1 signaling
0.82	GO:0090114	COPII-coated vesicle budding
0.65	GO:0015031	protein transport
0.63	GO:0035459	cargo loading into vesicle
0.60	GO:0051668	localization within membrane
0.46	GO:0070278	extracellular matrix constituent secretion
0.45	GO:0010842	retina layer formation
0.44	GO:0042462	eye photoreceptor cell development
0.44	GO:0001889	liver development
0.43	GO:0051216	cartilage development

0.61	GO:0005198	structural molecule activity
0.54	GO:0042802	identical protein binding
0.35	GO:0005179	hormone activity

0.80	GO:0030127	COPII vesicle coat
0.74	GO:0000139	Golgi membrane
0.61	GO:0061700	GATOR2 complex
0.60	GO:0031080	nuclear pore outer ring
0.58	GO:0005765	lysosomal membrane
0.56	GO:0000776	kinetochore
0.52	GO:0005654	nucleoplasm
0.44	GO:0070971	endoplasmic reticulum exit site
0.39	GO:0005789	endoplasmic reticulum membrane
0.38	GO:0070062	extracellular exosome

tr|T1EMC1|T1EMC1_HELRO
Uncharacterized protein
Search

ECH1

0.44	Enoyl-CoA isomerase

0.37	GO:0006635	fatty acid beta-oxidation
0.34	GO:0006397	mRNA processing

0.48	GO:0016853	isomerase activity
0.39	GO:0005102	receptor binding
0.34	GO:0003723	RNA binding
0.34	GO:0010181	FMN binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0016491	oxidoreductase activity
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.37	GO:0005777	peroxisome
0.36	GO:0005739	mitochondrion
0.35	GO:0019013	viral nucleocapsid
0.35	GO:0070062	extracellular exosome
0.34	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.48

EC:5

GO:0016853

tr|T1EMC2|T1EMC2_HELRO
Synaptotagmin 1c
Search

0.56	Synaptotagmin-1 (inferred by orthology to a C. elegans protein)

0.82	GO:0099643	signal release from synapse
0.82	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.76	GO:0006836	neurotransmitter transport
0.72	GO:0001505	regulation of neurotransmitter levels
0.68	GO:0051649	establishment of localization in cell
0.47	GO:0017158	regulation of calcium ion-dependent exocytosis
0.46	GO:0017156	calcium ion regulated exocytosis
0.46	GO:0097479	synaptic vesicle localization
0.46	GO:0099003	vesicle-mediated transport in synapse
0.46	GO:0050804	modulation of chemical synaptic transmission

0.81	GO:0005544	calcium-dependent phospholipid binding
0.46	GO:0000149	SNARE binding
0.44	GO:0050750	low-density lipoprotein particle receptor binding
0.44	GO:0048306	calcium-dependent protein binding
0.43	GO:0030276	clathrin binding
0.43	GO:0005509	calcium ion binding
0.41	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.40	GO:0001786	phosphatidylserine binding
0.38	GO:0005516	calmodulin binding
0.38	GO:0008022	protein C-terminus binding

0.82	GO:0008021	synaptic vesicle
0.47	GO:0099501	exocytic vesicle membrane
0.45	GO:0031045	dense core granule
0.44	GO:0042734	presynaptic membrane
0.43	GO:0030424	axon
0.40	GO:0005794	Golgi apparatus
0.40	GO:0042584	chromaffin granule membrane
0.40	GO:0005829	cytosol
0.39	GO:0043679	axon terminus
0.39	GO:0060076	excitatory synapse

tr|T1EMC3|T1EMC3_HELRO
Uncharacterized protein
Search

RBBP4

0.76	RB binding protein 4, chromatin remodeling factor

0.47	GO:0031497	chromatin assembly
0.47	GO:0034723	DNA replication-dependent nucleosome organization
0.46	GO:0006338	chromatin remodeling
0.46	GO:0034724	DNA replication-independent nucleosome organization
0.45	GO:0065004	protein-DNA complex assembly
0.42	GO:0016569	covalent chromatin modification
0.40	GO:0000122	negative regulation of transcription by RNA polymerase II
0.40	GO:0045814	negative regulation of gene expression, epigenetic
0.40	GO:0007379	segment specification
0.39	GO:0018393	internal peptidyl-lysine acetylation

0.48	GO:0042826	histone deacetylase binding
0.42	GO:0008094	DNA-dependent ATPase activity
0.40	GO:0031491	nucleosome binding
0.39	GO:0042393	histone binding
0.39	GO:0042054	histone methyltransferase activity
0.38	GO:0042803	protein homodimerization activity
0.36	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.36	GO:0031490	chromatin DNA binding
0.35	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.35	GO:0004402	histone acetyltransferase activity

0.61	GO:0005634	nucleus
0.51	GO:0033186	CAF-1 complex
0.48	GO:0017053	transcriptional repressor complex
0.47	GO:0034708	methyltransferase complex
0.45	GO:0000785	chromatin
0.44	GO:0070013	intracellular organelle lumen
0.43	GO:1904949	ATPase complex
0.42	GO:0005829	cytosol
0.40	GO:0031523	Myb complex
0.39	GO:0005700	polytene chromosome

0.35

GO:0004402

tr|T1EMC4|T1EMC4_HELRO
Uncharacterized protein
Search

0.54	V-type proton ATPase catalytic subunit A

0.75	GO:0015991	ATP hydrolysis coupled proton transport
0.62	GO:0046034	ATP metabolic process
0.53	GO:0036295	cellular response to increased oxygen levels
0.48	GO:0006879	cellular iron ion homeostasis
0.39	GO:0071456	cellular response to hypoxia
0.39	GO:0008593	regulation of Notch signaling pathway
0.37	GO:0030004	cellular monovalent inorganic cation homeostasis
0.36	GO:0045851	pH reduction
0.35	GO:0007446	imaginal disc growth
0.35	GO:0035149	lumen formation, open tracheal system

0.80	GO:0046961	proton-transporting ATPase activity, rotational mechanism
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0003677	DNA binding

0.80	GO:0033180	proton-transporting V-type ATPase, V1 domain
0.56	GO:0016324	apical plasma membrane
0.50	GO:0005902	microvillus
0.49	GO:0043209	myelin sheath
0.46	GO:0005765	lysosomal membrane
0.44	GO:0005829	cytosol
0.41	GO:0005739	mitochondrion
0.35	GO:0070062	extracellular exosome
0.35	GO:0033181	plasma membrane proton-transporting V-type ATPase complex
0.33	GO:0005887	integral component of plasma membrane

tr|T1EMC5|T1EMC5_HELRO
Sodium/potassium-transporting ATPase subunit alpha
Search

ATP1A3

0.64	Sodium/potassium-transporting ATPase subunit alpha-B

0.85	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient
0.75	GO:0090662	ATP hydrolysis coupled transmembrane transport
0.72	GO:0006814	sodium ion transport
0.71	GO:0006813	potassium ion transport
0.50	GO:0006883	cellular sodium ion homeostasis
0.50	GO:0086036	regulation of cardiac muscle cell membrane potential
0.49	GO:1990535	neuron projection maintenance
0.48	GO:0030007	cellular potassium ion homeostasis
0.48	GO:0008542	visual learning
0.48	GO:0140115	export across plasma membrane

0.85	GO:0005391	sodium:potassium-exchanging ATPase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.53	GO:0046872	metal ion binding
0.47	GO:0001540	amyloid-beta binding
0.45	GO:0051087	chaperone binding
0.43	GO:1901681	sulfur compound binding
0.38	GO:1990239	steroid hormone binding

0.49	GO:0042383	sarcolemma
0.48	GO:0005890	sodium:potassium-exchanging ATPase complex
0.48	GO:0043209	myelin sheath
0.46	GO:0043025	neuronal cell body
0.46	GO:0030424	axon
0.43	GO:0005794	Golgi apparatus
0.43	GO:0005783	endoplasmic reticulum
0.40	GO:0005634	nucleus
0.38	GO:0098794	postsynapse
0.37	GO:0098590	plasma membrane region

0.85

EC:3.6.3.9

GO:0005391

tr|T1EMC6|T1EMC6_HELRO
Uncharacterized protein
Search

CDC45

0.76	LOW QUALITY PROTEIN: cell division control protein 45 homolog

0.75	GO:0006270	DNA replication initiation
0.53	GO:0051301	cell division
0.51	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle
0.51	GO:1902977	mitotic DNA replication preinitiation complex assembly
0.49	GO:1902299	pre-replicative complex assembly involved in cell cycle DNA replication
0.49	GO:0031938	regulation of chromatin silencing at telomere
0.49	GO:0000727	double-strand break repair via break-induced replication
0.45	GO:0032392	DNA geometric change
0.41	GO:0006277	DNA amplification
0.39	GO:0030261	chromosome condensation

0.48	GO:0043138	3'-5' DNA helicase activity
0.48	GO:0003682	chromatin binding
0.46	GO:0003688	DNA replication origin binding
0.45	GO:0003697	single-stranded DNA binding
0.36	GO:0008270	zinc ion binding
0.35	GO:0005515	protein binding
0.32	GO:0022857	transmembrane transporter activity

0.51	GO:0005656	nuclear pre-replicative complex
0.49	GO:0005813	centrosome
0.48	GO:0031298	replication fork protection complex
0.48	GO:0031261	DNA replication preinitiation complex
0.34	GO:0005737	cytoplasm
0.32	GO:0000790	nuclear chromatin
0.30	GO:0031224	intrinsic component of membrane

tr|T1EMC7|T1EMC7_HELRO
Phosphoglycerate mutase
Search

GPMA

0.43	Phosphoglycerate mutase

0.70	GO:0006757	ATP generation from ADP
0.69	GO:0006090	pyruvate metabolic process
0.68	GO:0019319	hexose biosynthetic process
0.68	GO:0016052	carbohydrate catabolic process
0.67	GO:0019362	pyridine nucleotide metabolic process
0.67	GO:0006006	glucose metabolic process
0.36	GO:0043456	regulation of pentose-phosphate shunt
0.34	GO:0007520	myoblast fusion
0.33	GO:0016311	dephosphorylation

0.78	GO:0004619	phosphoglycerate mutase activity
0.52	GO:0004082	bisphosphoglycerate mutase activity
0.35	GO:0004083	bisphosphoglycerate 2-phosphatase activity

0.35

GO:0005829

cytosol

0.78	EC:5.4.2.1	GO:0004619
0.35	KEGG:R01516	GO:0004083

tr|T1EMC8|T1EMC8_HELRO
Uncharacterized protein
Search

0.54	Putative autophagic cell death

0.34

GO:0005515

protein binding

0.40	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

tr|T1EMC9|T1EMC9_HELRO
Uncharacterized protein
Search

DCTN5

0.86	Dynactin subunit 5

0.80	GO:0060976	coronary vasculature development
0.79	GO:0035904	aorta development
0.79	GO:0003281	ventricular septum development
0.41	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.39	GO:0006888	ER to Golgi vesicle-mediated transport

0.39	GO:0008780	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
0.36	GO:0005515	protein binding

0.77	GO:0031965	nuclear membrane
0.76	GO:0005813	centrosome
0.67	GO:0005654	nucleoplasm
0.46	GO:0000777	condensed chromosome kinetochore
0.37	GO:0005829	cytosol

0.39

EC:2.3.1.129

GO:0008780

tr|T1EMD0|T1EMD0_HELRO
Transmembrane 9 superfamily member
Search

TM9SF1

0.54	Transmembrane 9 superfamily member

0.44	GO:0007034	vacuolar transport
0.39	GO:0006914	autophagy
0.36	GO:0034613	cellular protein localization
0.35	GO:0015031	protein transport
0.35	GO:0046907	intracellular transport
0.34	GO:0099120	socially cooperative development
0.34	GO:0008654	phospholipid biosynthetic process
0.34	GO:0006909	phagocytosis
0.34	GO:0031589	cell-substrate adhesion
0.34	GO:0008283	cell proliferation

0.37	GO:0008536	Ran GTPase binding
0.34	GO:0016780	phosphotransferase activity, for other substituted phosphate groups

0.40	GO:0000421	autophagosome membrane
0.39	GO:0005765	lysosomal membrane
0.38	GO:0031410	cytoplasmic vesicle
0.30	GO:0016021	integral component of membrane

0.34

EC:2.7.8

GO:0016780

tr|T1EMD1|T1EMD1_HELRO
Uncharacterized protein
Search

0.41	EF-hand calcium-binding domain-containing protein 11

0.45	GO:0014823	response to activity
0.40	GO:1903525	regulation of membrane tubulation
0.39	GO:0032120	ascospore-type prospore membrane assembly
0.39	GO:0042991	transcription factor import into nucleus
0.39	GO:0000742	karyogamy involved in conjugation with cellular fusion
0.39	GO:0051300	spindle pole body organization
0.39	GO:0006607	NLS-bearing protein import into nucleus
0.39	GO:0016237	lysosomal microautophagy
0.39	GO:0007114	cell budding
0.39	GO:0042144	vacuole fusion, non-autophagic

0.70	GO:0005509	calcium ion binding
0.43	GO:0046982	protein heterodimerization activity
0.41	GO:0048306	calcium-dependent protein binding
0.39	GO:0051019	mitogen-activated protein kinase binding
0.37	GO:0003677	DNA binding
0.37	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.36	GO:0009931	calcium-dependent protein serine/threonine kinase activity
0.36	GO:0051015	actin filament binding
0.35	GO:0005246	calcium channel regulator activity
0.35	GO:0004683	calmodulin-dependent protein kinase activity

0.43	GO:0000786	nucleosome
0.40	GO:0005634	nucleus
0.40	GO:0045160	myosin I complex
0.40	GO:0005823	central plaque of spindle pole body
0.39	GO:1990819	actin fusion focus
0.39	GO:0005628	prospore membrane
0.39	GO:0031097	medial cortex
0.39	GO:0000131	incipient cellular bud site
0.38	GO:0005934	cellular bud tip
0.38	GO:0051286	cell tip

0.37

GO:0032440

tr|T1EMD2|T1EMD2_HELRO
Uncharacterized protein
Search

RPS23

0.53	Small subunit ribosomal protein S23e

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.37	GO:0065004	protein-DNA complex assembly
0.34	GO:2001141	regulation of RNA biosynthetic process
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression
0.34	GO:0016070	RNA metabolic process
0.34	GO:0034654	nucleobase-containing compound biosynthetic process

0.64	GO:0003735	structural constituent of ribosome
0.38	GO:0019843	rRNA binding
0.38	GO:0017025	TBP-class protein binding
0.36	GO:0017112	Rab guanyl-nucleotide exchange factor activity
0.34	GO:0046872	metal ion binding
0.33	GO:0003899	DNA-directed 5'-3' RNA polymerase activity

0.69	GO:0015935	small ribosomal subunit
0.44	GO:0022626	cytosolic ribosome
0.38	GO:0042788	polysomal ribosome
0.33	GO:0005783	endoplasmic reticulum
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0003899

tr|T1EMD3|T1EMD3_HELRO
Uncharacterized protein
Search

0.41	Phosphopyruvate hydratase

0.71	GO:0006757	ATP generation from ADP
0.69	GO:0006090	pyruvate metabolic process
0.68	GO:0016052	carbohydrate catabolic process
0.67	GO:0046496	nicotinamide nucleotide metabolic process
0.35	GO:0052302	modulation by organism of defense-related nitric oxide production in other organism involved in symbiotic interaction
0.34	GO:0044044	interaction with host via substance in symbiont surface
0.34	GO:0052565	response to defense-related host nitric oxide production
0.34	GO:0006006	glucose metabolic process
0.33	GO:0044282	small molecule catabolic process
0.33	GO:0052031	modulation by symbiont of host defense response

0.78	GO:0004634	phosphopyruvate hydratase activity
0.64	GO:0000287	magnesium ion binding
0.33	GO:0019904	protein domain specific binding
0.33	GO:0004252	serine-type endopeptidase activity
0.33	GO:0046537	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
0.32	GO:0030145	manganese ion binding

0.77	GO:0000015	phosphopyruvate hydratase complex
0.51	GO:0009986	cell surface
0.45	GO:0005576	extracellular region
0.38	GO:0005634	nucleus
0.33	GO:0098552	side of membrane
0.32	GO:0044459	plasma membrane part
0.30	GO:0016021	integral component of membrane

0.78

EC:4.2.1.11

GO:0004634

tr|T1EMD4|T1EMD4_HELRO
DNA-directed RNA polymerase subunit
Search

POLR2I

0.51	DNA-directed RNA polymerase subunit

0.79	GO:0006379	mRNA cleavage
0.57	GO:0006351	transcription, DNA-templated
0.46	GO:0006283	transcription-coupled nucleotide-excision repair
0.35	GO:0035019	somatic stem cell population maintenance
0.34	GO:0060964	regulation of gene silencing by miRNA
0.34	GO:0008543	fibroblast growth factor receptor signaling pathway
0.34	GO:0016073	snRNA metabolic process
0.34	GO:0050434	positive regulation of viral transcription
0.34	GO:0000398	mRNA splicing, via spliceosome
0.34	GO:0006370	7-methylguanosine mRNA capping

0.69	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.61	GO:0008270	zinc ion binding
0.50	GO:0003676	nucleic acid binding

0.68	GO:0005730	nucleolus
0.53	GO:0005665	DNA-directed RNA polymerase II, core complex

0.69

GO:0003899

tr|T1EMD5|T1EMD5_HELRO
Uncharacterized protein
Search

CRYZ

0.43	Zinc-binding alcohol dehydrogenase

0.53	GO:0055114	oxidation-reduction process
0.47	GO:0051289	protein homotetramerization
0.45	GO:0042178	xenobiotic catabolic process
0.34	GO:0007601	visual perception
0.32	GO:0006508	proteolysis

0.54	GO:0016491	oxidoreductase activity
0.53	GO:0008270	zinc ion binding
0.47	GO:0003730	mRNA 3'-UTR binding
0.46	GO:0070402	NADPH binding
0.42	GO:0070404	NADH binding
0.34	GO:0005212	structural constituent of eye lens
0.34	GO:0004315	3-oxoacyl-[acyl-carrier-protein] synthase activity
0.33	GO:0005515	protein binding
0.32	GO:0003677	DNA binding
0.32	GO:0031177	phosphopantetheine binding

0.43	GO:0005829	cytosol
0.35	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.54

GO:0016491

tr|T1EMD6|T1EMD6_HELRO
Uncharacterized protein
Search

0.45	Ribosomal protein S6 kinase 2 alpha

0.63	GO:0006468	protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.42	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.41	GO:2000491	positive regulation of hepatic stellate cell activation
0.40	GO:0006915	apoptotic process
0.40	GO:0045944	positive regulation of transcription by RNA polymerase II
0.39	GO:0006974	cellular response to DNA damage stimulus
0.38	GO:2000381	negative regulation of mesoderm development
0.38	GO:0045992	negative regulation of embryonic development
0.37	GO:0070373	negative regulation of ERK1 and ERK2 cascade

0.70	GO:0004674	protein serine/threonine kinase activity
0.64	GO:0000287	magnesium ion binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.39	GO:0004712	protein serine/threonine/tyrosine kinase activity
0.36	GO:0019901	protein kinase binding

0.45	GO:0005622	intracellular
0.40	GO:0043227	membrane-bounded organelle
0.40	GO:0043233	organelle lumen
0.38	GO:0043228	non-membrane-bounded organelle
0.33	GO:1990904	ribonucleoprotein complex
0.30	GO:0016020	membrane

0.70

GO:0004674

tr|T1EMD7|T1EMD7_HELRO
Uncharacterized protein
Search

TARDBP

0.87	TAR DNA-binding protein 43

0.45	GO:0071765	nuclear inner membrane organization
0.44	GO:0043922	negative regulation by host of viral transcription
0.43	GO:0070935	3'-UTR-mediated mRNA stabilization
0.42	GO:0006366	transcription by RNA polymerase II
0.41	GO:0045944	positive regulation of transcription by RNA polymerase II
0.41	GO:0008380	RNA splicing
0.40	GO:0001933	negative regulation of protein phosphorylation
0.40	GO:0042981	regulation of apoptotic process
0.40	GO:0051726	regulation of cell cycle
0.39	GO:0048675	axon extension

0.59	GO:0003723	RNA binding
0.47	GO:0003677	DNA binding
0.44	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding
0.40	GO:0042802	identical protein binding

0.39	GO:0005654	nucleoplasm
0.34	GO:0005726	perichromatin fibrils
0.32	GO:0005737	cytoplasm

tr|T1EMD8|T1EMD8_HELRO
Uncharacterized protein
Search

0.45	GO:0010951	negative regulation of endopeptidase activity
0.38	GO:0060570	negative regulation of peptide hormone processing
0.37	GO:0006508	proteolysis

0.46	GO:0004867	serine-type endopeptidase inhibitor activity
0.37	GO:0008233	peptidase activity
0.36	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.33	GO:0016740	transferase activity

0.73	GO:0005615	extracellular space
0.34	GO:0031012	extracellular matrix
0.30	GO:0031224	intrinsic component of membrane

0.37

GO:0008233

tr|T1EMD9|T1EMD9_HELRO
Uncharacterized protein
Search

NAT9

0.56	Phosphoglucosamine acetyltransferase

0.33	GO:0016573	histone acetylation
0.32	GO:0055085	transmembrane transport
0.32	GO:0022900	electron transport chain
0.32	GO:0006520	cellular amino acid metabolic process

0.67	GO:0008080	N-acetyltransferase activity
0.32	GO:0005515	protein binding
0.32	GO:0022857	transmembrane transporter activity
0.32	GO:0009055	electron transfer activity

0.32	GO:0005829	cytosol
0.32	GO:0043234	protein complex
0.32	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.67

GO:0008080

tr|T1EME0|T1EME0_HELRO
Uncharacterized protein
Search

0.39	Serine protease inhibitor serpin

0.57	GO:0010951	negative regulation of endopeptidase activity
0.47	GO:0006508	proteolysis
0.47	GO:0030193	regulation of blood coagulation
0.45	GO:0010757	negative regulation of plasminogen activation
0.45	GO:0061108	seminal vesicle epithelium development
0.45	GO:0042628	mating plug formation
0.44	GO:0048711	positive regulation of astrocyte differentiation
0.44	GO:0021683	cerebellar granular layer morphogenesis
0.43	GO:0010766	negative regulation of sodium ion transport
0.43	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling

0.58	GO:0004867	serine-type endopeptidase inhibitor activity
0.48	GO:0008233	peptidase activity
0.46	GO:0008201	heparin binding
0.40	GO:0005102	receptor binding
0.38	GO:0002020	protease binding
0.37	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.32	GO:0016740	transferase activity

0.73	GO:0005615	extracellular space
0.44	GO:0031232	extrinsic component of external side of plasma membrane
0.44	GO:0031091	platelet alpha granule
0.42	GO:0031594	neuromuscular junction
0.41	GO:0031012	extracellular matrix
0.40	GO:0005829	cytosol
0.35	GO:0005794	Golgi apparatus
0.35	GO:0005654	nucleoplasm
0.35	GO:1903561	extracellular vesicle
0.30	GO:0016021	integral component of membrane

0.48

GO:0008233

tr|T1EME1|T1EME1_HELRO
Uncharacterized protein
Search

0.45	GO:0000398	mRNA splicing, via spliceosome
0.34	GO:0006427	histidyl-tRNA aminoacylation

0.63	GO:0008270	zinc ion binding
0.51	GO:0003676	nucleic acid binding
0.36	GO:0016875	ligase activity, forming carbon-oxygen bonds
0.36	GO:0140101	catalytic activity, acting on a tRNA
0.33	GO:0005515	protein binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.47	GO:0046540	U4/U6 x U5 tri-snRNP complex
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.36

EC:6.1

GO:0016875

tr|T1EME2|T1EME2_HELRO
Uncharacterized protein
Search

tr|T1EME3|T1EME3_HELRO
Uncharacterized protein
Search

0.49	GO:1903506	regulation of nucleic acid-templated transcription
0.49	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.49	GO:0010468	regulation of gene expression
0.38	GO:0006351	transcription, DNA-templated
0.36	GO:0040034	regulation of development, heterochronic
0.33	GO:0016540	protein autoprocessing
0.33	GO:0008654	phospholipid biosynthetic process
0.33	GO:0046337	phosphatidylethanolamine metabolic process
0.32	GO:0045017	glycerolipid biosynthetic process

0.51	GO:0003676	nucleic acid binding
0.47	GO:0046872	metal ion binding
0.43	GO:0003700	DNA binding transcription factor activity
0.33	GO:0004609	phosphatidylserine decarboxylase activity
0.32	GO:0005515	protein binding

0.43	GO:0005634	nucleus
0.33	GO:0031305	integral component of mitochondrial inner membrane

0.33	EC:4.1.1.65	GO:0004609
0.33	KEGG:R02055	GO:0004609

tr|T1EME4|T1EME4_HELRO
Uncharacterized protein
Search

0.34	Glutathione synthetase

0.79	GO:0006750	glutathione biosynthetic process
0.39	GO:0090423	phytochelatin-metal complex formation
0.38	GO:0098849	cellular detoxification of cadmium ion
0.38	GO:0046938	phytochelatin biosynthetic process
0.37	GO:0034635	glutathione transport
0.36	GO:0071722	detoxification of arsenic-containing substance
0.36	GO:0045471	response to ethanol
0.35	GO:0006520	cellular amino acid metabolic process

0.81	GO:0043295	glutathione binding
0.81	GO:0004363	glutathione synthase activity
0.71	GO:0042803	protein homodimerization activity
0.61	GO:0000287	magnesium ion binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.39	GO:0036087	glutathione synthase complex
0.37	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.81	EC:6.3.2.3	GO:0004363
0.81	KEGG:R00497	GO:0004363

tr|T1EME5|T1EME5_HELRO
Uncharacterized protein
Search

0.76	Cytosolic Fe-S cluster assembly factor NUBP2

0.71	GO:0016226	iron-sulfur cluster assembly
0.35	GO:0030001	metal ion transport
0.34	GO:0051260	protein homooligomerization
0.34	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.34	GO:0002098	tRNA wobble uridine modification
0.34	GO:0055085	transmembrane transport

0.64	GO:0051539	4 iron, 4 sulfur cluster binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0046872	metal ion binding
0.36	GO:0046873	metal ion transmembrane transporter activity
0.34	GO:0000175	3'-5'-exoribonuclease activity
0.33	GO:0004519	endonuclease activity
0.33	GO:0005515	protein binding

0.47	GO:0005737	cytoplasm
0.33	GO:1904949	ATPase complex
0.33	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.34

EC:3.1.13

GO:0000175

tr|T1EME6|T1EME6_HELRO
Sideroflexin
Search

SFXN1

0.80	Sideroflexin

0.60	GO:0034220	ion transmembrane transport
0.51	GO:0030218	erythrocyte differentiation
0.48	GO:0006826	iron ion transport
0.38	GO:0055072	iron ion homeostasis
0.34	GO:0006626	protein targeting to mitochondrion

0.60

GO:0015075

ion transmembrane transporter activity

0.59	GO:0031966	mitochondrial membrane
0.43	GO:0019866	organelle inner membrane
0.34	GO:0031968	organelle outer membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1EME7|T1EME7_HELRO
Uncharacterized protein
Search

HMGB3

0.84	High-mobility group box 3

0.52	GO:0032392	DNA geometric change
0.48	GO:0045578	negative regulation of B cell differentiation
0.45	GO:0045638	negative regulation of myeloid cell differentiation
0.36	GO:0040025	vulval development
0.36	GO:0045087	innate immune response
0.36	GO:0001708	cell fate specification
0.36	GO:0008406	gonad development
0.35	GO:2001141	regulation of RNA biosynthetic process
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression

0.60	GO:0000400	four-way junction DNA binding
0.60	GO:0008301	DNA binding, bending
0.38	GO:0003723	RNA binding
0.35	GO:0044212	transcription regulatory region DNA binding
0.34	GO:0003690	double-stranded DNA binding
0.32	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.36	GO:0005694	chromosome
0.33	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1EME8|T1EME8_HELRO
Uncharacterized protein
Search

0.78	BR serine/threonine-protein kinase 2

0.63	GO:0006468	protein phosphorylation
0.42	GO:0007528	neuromuscular junction development
0.42	GO:0007095	mitotic G2 DNA damage checkpoint
0.41	GO:0007409	axonogenesis
0.41	GO:0007163	establishment or maintenance of cell polarity
0.41	GO:0006487	protein N-linked glycosylation
0.41	GO:0051298	centrosome duplication
0.40	GO:0009411	response to UV
0.37	GO:0006470	protein dephosphorylation
0.37	GO:0035556	intracellular signal transduction

0.64	GO:0004672	protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0043015	gamma-tubulin binding
0.40	GO:0019901	protein kinase binding
0.38	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.38	GO:0000287	magnesium ion binding
0.35	GO:0030983	mismatched DNA binding

0.40	GO:0005813	centrosome
0.39	GO:0030054	cell junction
0.39	GO:0005634	nucleus
0.38	GO:0070013	intracellular organelle lumen
0.35	GO:0005737	cytoplasm
0.35	GO:0045202	synapse
0.35	GO:0097458	neuron part
0.34	GO:0012505	endomembrane system
0.34	GO:0120038	plasma membrane bounded cell projection part
0.33	GO:0097708	intracellular vesicle

0.38

GO:0008138

tr|T1EME9|T1EME9_HELRO
Uncharacterized protein
Search

SNRPF

0.89	Small nuclear ribonucleoprotein polypeptide F

0.81	GO:0000387	spliceosomal snRNP assembly
0.35	GO:0043606	formamide metabolic process
0.35	GO:0006548	histidine catabolic process
0.35	GO:0008334	histone mRNA metabolic process
0.34	GO:0006369	termination of RNA polymerase II transcription
0.34	GO:0006536	glutamate metabolic process
0.34	GO:0008217	regulation of blood pressure
0.34	GO:0097746	regulation of blood vessel diameter
0.34	GO:0051170	nuclear import
0.33	GO:0007186	G-protein coupled receptor signaling pathway

0.56	GO:0003723	RNA binding
0.35	GO:0001604	urotensin II receptor activity
0.34	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
0.33	GO:0005515	protein binding

0.80	GO:0005732	small nucleolar ribonucleoprotein complex
0.76	GO:0005681	spliceosomal complex
0.58	GO:0019013	viral nucleocapsid
0.53	GO:0005685	U1 snRNP
0.52	GO:0005683	U7 snRNP
0.52	GO:0005687	U4 snRNP
0.51	GO:0034709	methylosome
0.51	GO:0034715	pICln-Sm protein complex
0.51	GO:0034719	SMN-Sm protein complex
0.44	GO:0005829	cytosol

0.34

EC:3.5.2

GO:0016812

tr|T1EMF0|T1EMF0_HELRO
Uncharacterized protein
Search

0.58	Sodium/potassium-transporting ATPase subunit alpha

0.84	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient
0.75	GO:0090662	ATP hydrolysis coupled transmembrane transport
0.72	GO:0006814	sodium ion transport
0.71	GO:0006813	potassium ion transport
0.50	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.48	GO:0030317	flagellated sperm motility
0.43	GO:0030641	regulation of cellular pH
0.43	GO:0009566	fertilization
0.42	GO:0007283	spermatogenesis
0.42	GO:0042391	regulation of membrane potential

0.84	GO:0005391	sodium:potassium-exchanging ATPase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0046872	metal ion binding
0.35	GO:0008900	potassium:proton exchanging ATPase activity

0.35	GO:0005886	plasma membrane
0.35	GO:0005918	septate junction
0.34	GO:0090533	cation-transporting ATPase complex
0.33	GO:0005634	nucleus

0.84

EC:3.6.3.9

GO:0005391

tr|T1EMF1|T1EMF1_HELRO
Uncharacterized protein
Search

CDKAL1

0.85	Threonylcarbamoyladenosine tRNA methylthiotransferase

0.67	GO:0006400	tRNA modification
0.49	GO:1990145	maintenance of translational fidelity
0.34	GO:0006351	transcription, DNA-templated
0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression
0.32	GO:0055114	oxidation-reduction process

0.67	GO:0051539	4 iron, 4 sulfur cluster binding
0.51	GO:0035598	N6-threonylcarbomyladenosine methylthiotransferase activity
0.41	GO:0061712	tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
0.35	GO:0046983	protein dimerization activity
0.34	GO:0003700	DNA binding transcription factor activity
0.34	GO:0046872	metal ion binding
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.34	GO:0003677	DNA binding

0.46	GO:0005791	rough endoplasmic reticulum
0.36	GO:0005667	transcription factor complex
0.36	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.41

EC:2.8.4.5

GO:0061712

tr|T1EMF2|T1EMF2_HELRO
Uncharacterized protein
Search

RAB6A

0.40	GTP-binding protein ryh1

0.43	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.43	GO:0006891	intra-Golgi vesicle-mediated transport
0.42	GO:0042147	retrograde transport, endosome to Golgi
0.40	GO:0060471	cortical granule exocytosis
0.38	GO:1904515	positive regulation of TORC2 signaling
0.35	GO:0072600	establishment of protein localization to Golgi
0.34	GO:0048015	phosphatidylinositol-mediated signaling
0.34	GO:0015031	protein transport
0.34	GO:0046854	phosphatidylinositol phosphorylation

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005515	protein binding
0.32	GO:0016301	kinase activity

0.44	GO:0005794	Golgi apparatus
0.39	GO:0005829	cytosol
0.39	GO:0060473	cortical granule
0.36	GO:0031984	organelle subcompartment
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0031080	nuclear pore outer ring
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1EMF3|T1EMF3_HELRO
Uncharacterized protein
Search

0.29	Protein phosphatase 1A, magnesium-dependent, alpha isoform (Fragment)

0.72	GO:0006470	protein dephosphorylation
0.56	GO:0010991	negative regulation of SMAD protein complex assembly
0.56	GO:0042347	negative regulation of NF-kappaB import into nucleus
0.53	GO:0006499	N-terminal protein myristoylation
0.53	GO:0046827	positive regulation of protein export from nucleus
0.53	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.53	GO:0030514	negative regulation of BMP signaling pathway
0.52	GO:0030177	positive regulation of Wnt signaling pathway
0.51	GO:0071560	cellular response to transforming growth factor beta stimulus
0.50	GO:0016055	Wnt signaling pathway

0.77	GO:0004722	protein serine/threonine phosphatase activity
0.72	GO:0030145	manganese ion binding
0.64	GO:0000287	magnesium ion binding
0.55	GO:0070412	R-SMAD binding
0.35	GO:0004871	signal transducer activity
0.34	GO:0008022	protein C-terminus binding
0.32	GO:0003677	DNA binding

0.47	GO:0005829	cytosol
0.44	GO:0005634	nucleus
0.41	GO:0005886	plasma membrane
0.34	GO:0034704	calcium channel complex
0.34	GO:0043005	neuron projection
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0044446	intracellular organelle part

tr|T1EMF4|T1EMF4_HELRO
Uncharacterized protein
Search

TMED7

0.86	Transmembrane emp24 protein transport domain containing 7

0.38	GO:0007165	signal transduction
0.36	GO:2000494	positive regulation of interleukin-18-mediated signaling pathway
0.36	GO:0071651	positive regulation of chemokine (C-C motif) ligand 5 production
0.36	GO:0070671	response to interleukin-12
0.35	GO:0034145	positive regulation of toll-like receptor 4 signaling pathway
0.35	GO:0032729	positive regulation of interferon-gamma production
0.35	GO:0032755	positive regulation of interleukin-6 production
0.35	GO:0071222	cellular response to lipopolysaccharide
0.35	GO:0002218	activation of innate immune response
0.35	GO:0015031	protein transport

0.34	GO:0005543	phospholipid binding
0.33	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.33	GO:0004450	isocitrate dehydrogenase (NADP+) activity
0.33	GO:0005506	iron ion binding
0.32	GO:0051287	NAD binding
0.32	GO:0000287	magnesium ion binding

0.44	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.41	GO:0005794	Golgi apparatus
0.40	GO:0005783	endoplasmic reticulum
0.36	GO:0031410	cytoplasmic vesicle
0.36	GO:0012506	vesicle membrane
0.35	GO:0070062	extracellular exosome
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0098805	whole membrane
0.35	GO:0098588	bounding membrane of organelle
0.35	GO:0031984	organelle subcompartment

0.33

EC:1.13.11

GO:0016702

tr|T1EMF5|T1EMF5_HELRO
Uncharacterized protein
Search

GGPS1

0.52	Geranylgeranyl diphosphate synthase type III

0.71	GO:0008299	isoprenoid biosynthetic process
0.43	GO:0008354	germ cell migration
0.42	GO:0035050	embryonic heart tube development
0.41	GO:0048477	oogenesis
0.37	GO:0033383	geranyl diphosphate metabolic process
0.37	GO:0033385	geranylgeranyl diphosphate metabolic process
0.36	GO:0045338	farnesyl diphosphate metabolic process
0.35	GO:0045540	regulation of cholesterol biosynthetic process
0.35	GO:0006695	cholesterol biosynthetic process
0.34	GO:0008654	phospholipid biosynthetic process

0.50	GO:0016740	transferase activity
0.46	GO:0042802	identical protein binding
0.33	GO:0046872	metal ion binding
0.32	GO:0003723	RNA binding

0.33

GO:0005829

cytosol

0.50

GO:0016740

tr|T1EMF6|T1EMF6_HELRO
Uncharacterized protein
Search

RHOJ

0.75	Gtpase rho

0.77	GO:0007264	small GTPase mediated signal transduction
0.54	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis
0.54	GO:0061299	retina vasculature morphogenesis in camera-type eye
0.48	GO:0030036	actin cytoskeleton organization
0.45	GO:0008360	regulation of cell shape
0.37	GO:0051301	cell division
0.35	GO:0007516	hemocyte development
0.35	GO:0035099	hemocyte migration
0.35	GO:0035011	melanotic encapsulation of foreign target
0.35	GO:0007298	border follicle cell migration

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding
0.33	GO:0005509	calcium ion binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0003677	DNA binding
0.32	GO:0008144	drug binding

0.45	GO:0005622	intracellular
0.35	GO:0070062	extracellular exosome
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1EMF7|T1EMF7_HELRO
Uncharacterized protein
Search

ALDH7A1

0.61	Alpha-aminoadipic semialdehyde dehydrogenase

0.53	GO:0055114	oxidation-reduction process
0.45	GO:0033339	pectoral fin development
0.44	GO:0051216	cartilage development
0.43	GO:0043010	camera-type eye development
0.36	GO:0019285	glycine betaine biosynthetic process from choline
0.36	GO:0009269	response to desiccation
0.35	GO:0009737	response to abscisic acid
0.35	GO:0009651	response to salt stress
0.35	GO:0042426	choline catabolic process
0.34	GO:0006081	cellular aldehyde metabolic process

0.69	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.33	GO:0005515	protein binding
0.32	GO:1901265	nucleoside phosphate binding
0.32	GO:0036094	small molecule binding

0.44	GO:0005829	cytosol
0.41	GO:0005739	mitochondrion
0.34	GO:0070062	extracellular exosome
0.34	GO:0005634	nucleus
0.33	GO:0043233	organelle lumen
0.32	GO:0044446	intracellular organelle part

0.69

EC:1.2.1

GO:0016620

tr|T1EMF8|T1EMF8_HELRO
Uncharacterized protein
Search

0.59	Beta-3 adrenergic receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.54	GO:0007210	serotonin receptor signaling pathway
0.48	GO:0019933	cAMP-mediated signaling
0.47	GO:0042311	vasodilation
0.40	GO:1901699	cellular response to nitrogen compound
0.40	GO:0060359	response to ammonium ion
0.39	GO:0071310	cellular response to organic substance
0.39	GO:0071495	cellular response to endogenous stimulus
0.39	GO:0035690	cellular response to drug
0.38	GO:1901701	cellular response to oxygen-containing compound

0.72	GO:0004930	G-protein coupled receptor activity
0.59	GO:0030594	neurotransmitter receptor activity
0.55	GO:0099589	serotonin receptor activity
0.41	GO:0051378	serotonin binding
0.33	GO:0035240	dopamine binding
0.33	GO:0044212	transcription regulatory region DNA binding
0.33	GO:0005509	calcium ion binding
0.32	GO:0001653	peptide receptor activity
0.32	GO:0003700	DNA binding transcription factor activity

0.51	GO:0005887	integral component of plasma membrane
0.35	GO:0005622	intracellular
0.33	GO:0031526	brush border membrane
0.33	GO:0060170	ciliary membrane
0.33	GO:0097730	non-motile cilium

tr|T1EMF9|T1EMF9_HELRO
Uncharacterized protein
Search

0.76	H member 1 family protein, potassium voltage-gated channel subfamily

0.73	GO:0071805	potassium ion transmembrane transport
0.71	GO:0034765	regulation of ion transmembrane transport
0.63	GO:0023014	signal transduction by protein phosphorylation
0.60	GO:0000160	phosphorelay signal transduction system
0.48	GO:0021576	hindbrain formation
0.46	GO:0071277	cellular response to calcium ion
0.45	GO:0001756	somitogenesis
0.44	GO:0048015	phosphatidylinositol-mediated signaling
0.43	GO:0042391	regulation of membrane potential
0.43	GO:0042127	regulation of cell proliferation

0.78	GO:0005249	voltage-gated potassium channel activity
0.63	GO:0000155	phosphorelay sensor kinase activity
0.45	GO:1902936	phosphatidylinositol bisphosphate binding
0.36	GO:0071889	14-3-3 protein binding
0.35	GO:0044325	ion channel binding
0.35	GO:0005516	calmodulin binding
0.35	GO:0030551	cyclic nucleotide binding
0.35	GO:0019901	protein kinase binding
0.34	GO:0046982	protein heterodimerization activity
0.34	GO:0042802	identical protein binding

0.61	GO:0005887	integral component of plasma membrane
0.46	GO:0031901	early endosome membrane
0.43	GO:0034705	potassium channel complex
0.38	GO:0009986	cell surface
0.37	GO:0043231	intracellular membrane-bounded organelle
0.36	GO:0042734	presynaptic membrane
0.36	GO:0043204	perikaryon
0.36	GO:0030673	axolemma
0.36	GO:0014069	postsynaptic density
0.35	GO:0030425	dendrite

0.63

EC:2.7.3

GO:0000155

tr|T1EMG0|T1EMG0_HELRO
Protein pelota homolog
Search

0.85	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay
0.84	GO:0070481	nuclear-transcribed mRNA catabolic process, non-stop decay
0.83	GO:0071025	RNA surveillance
0.62	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.47	GO:0051078	meiotic nuclear envelope disassembly
0.46	GO:0048132	female germ-line stem cell asymmetric division
0.46	GO:0048137	spermatocyte division
0.45	GO:0030718	germ-line stem cell population maintenance
0.45	GO:0000212	meiotic spindle organization
0.44	GO:0001745	compound eye morphogenesis

0.64	GO:0004519	endonuclease activity
0.52	GO:0046872	metal ion binding
0.40	GO:0043022	ribosome binding

0.59	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.46	GO:1990533	Dom34-Hbs1 complex
0.30	GO:0016020	membrane

tr|T1EMG1|T1EMG1_HELRO
Uncharacterized protein
Search

GALE

0.41	UDP-glucose 4-epimerase GalE

0.76

GO:0006012

galactose metabolic process

0.78	GO:0003978	UDP-glucose 4-epimerase activity
0.41	GO:0050662	coenzyme binding

0.30

GO:0031224

intrinsic component of membrane

0.78

EC:5.1.3.2

GO:0003978

tr|T1EMG2|T1EMG2_HELRO
Uncharacterized protein
Search

0.73	GO:0016079	synaptic vesicle exocytosis
0.38	GO:0007520	myoblast fusion
0.37	GO:0010996	response to auditory stimulus
0.37	GO:0050885	neuromuscular process controlling balance
0.35	GO:0007605	sensory perception of sound
0.35	GO:0140029	exocytic process
0.34	GO:0043623	cellular protein complex assembly
0.34	GO:0090102	cochlea development
0.34	GO:0001778	plasma membrane repair
0.34	GO:0006906	vesicle fusion

0.62	GO:0005509	calcium ion binding
0.36	GO:0035612	AP-2 adaptor complex binding
0.34	GO:0005544	calcium-dependent phospholipid binding

0.69	GO:0098793	presynapse
0.36	GO:0099501	exocytic vesicle membrane
0.35	GO:0016323	basolateral plasma membrane
0.35	GO:0097060	synaptic membrane
0.35	GO:0030054	cell junction
0.34	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0045178	basal part of cell
0.34	GO:0030315	T-tubule
0.34	GO:0045177	apical part of cell
0.34	GO:0030027	lamellipodium

tr|T1EMG3|T1EMG3_HELRO
Uncharacterized protein
Search

0.91	Translocon-associated complex TRAP gamma subunit

0.76	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.30	GO:0008152	metabolic process

0.33

GO:0016874

ligase activity

0.45	GO:0005622	intracellular
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0044422	organelle part
0.33	GO:0043227	membrane-bounded organelle
0.33	GO:0098796	membrane protein complex
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:6

GO:0016874

tr|T1EMG4|T1EMG4_HELRO
Uncharacterized protein
Search

0.74	Transcriptional repressor scratch 1 (Fragment)

0.55	GO:0000122	negative regulation of transcription by RNA polymerase II
0.55	GO:0001837	epithelial to mesenchymal transition
0.54	GO:0060806	negative regulation of cell differentiation involved in embryonic placenta development
0.54	GO:0010957	negative regulation of vitamin D biosynthetic process
0.53	GO:2000810	regulation of bicellular tight junction assembly
0.53	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator
0.53	GO:0061314	Notch signaling involved in heart development
0.52	GO:0007369	gastrulation
0.52	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
0.52	GO:0010718	positive regulation of epithelial to mesenchymal transition

0.55	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.53	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.52	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.48	GO:0019900	kinase binding
0.44	GO:0000987	proximal promoter sequence-specific DNA binding
0.43	GO:0051059	NF-kappaB binding
0.41	GO:0005507	copper ion binding
0.32	GO:0008270	zinc ion binding

0.51	GO:0005721	pericentric heterochromatin
0.48	GO:0005634	nucleus
0.44	GO:0005829	cytosol
0.43	GO:0005667	transcription factor complex
0.33	GO:0043233	organelle lumen

tr|T1EMG5|T1EMG5_HELRO
Uncharacterized protein
Search

PRPF18

0.86	Pre-mRNA-processing factor 18

0.71	GO:0008380	RNA splicing
0.47	GO:0071048	nuclear retention of unspliced pre-mRNA at the site of transcription
0.42	GO:0006397	mRNA processing
0.42	GO:0022618	ribonucleoprotein complex assembly
0.34	GO:0032269	negative regulation of cellular protein metabolic process

0.46

GO:0000386

second spliceosomal transesterification activity

0.74	GO:0005681	spliceosomal complex
0.45	GO:0005682	U5 snRNP
0.44	GO:0046540	U4/U6 x U5 tri-snRNP complex
0.42	GO:0016607	nuclear speck
0.30	GO:0016020	membrane

tr|T1EMG6|T1EMG6_HELRO
Uncharacterized protein
Search

TMEM68

0.39	Transmembrane protein 68 (inferred by orthology to a human protein)

0.35	GO:0098869	cellular oxidant detoxification
0.35	GO:0045454	cell redox homeostasis
0.33	GO:0009890	negative regulation of biosynthetic process
0.33	GO:0055114	oxidation-reduction process
0.31	GO:0055085	transmembrane transport

0.63	GO:0016746	transferase activity, transferring acyl groups
0.35	GO:0051920	peroxiredoxin activity

0.30	GO:0016021	integral component of membrane
0.30	GO:0005623	cell

0.63

EC:2.3

GO:0016746

tr|T1EMG7|T1EMG7_HELRO
Uncharacterized protein
Search

tr|T1EMG8|T1EMG8_HELRO
Uncharacterized protein
Search

PRMT1

0.84	Arginine methyltransferase 1 variant 1

0.73	GO:0008213	protein alkylation
0.67	GO:0043414	macromolecule methylation
0.51	GO:0018195	peptidyl-arginine modification
0.48	GO:0016570	histone modification
0.45	GO:0009790	embryo development
0.43	GO:0060026	convergent extension
0.39	GO:0045653	negative regulation of megakaryocyte differentiation
0.38	GO:1903506	regulation of nucleic acid-templated transcription
0.38	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.38	GO:0010468	regulation of gene expression

0.63	GO:0008168	methyltransferase activity
0.40	GO:0140096	catalytic activity, acting on a protein
0.37	GO:0048273	mitogen-activated protein kinase p38 binding
0.36	GO:0008327	methyl-CpG binding
0.35	GO:0030519	snoRNP binding
0.35	GO:0042802	identical protein binding
0.34	GO:0003713	transcription coactivator activity
0.33	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.32	GO:0016301	kinase activity
0.32	GO:0003723	RNA binding

0.41	GO:0005829	cytosol
0.40	GO:0005654	nucleoplasm
0.36	GO:0034709	methylosome
0.32	GO:0043234	protein complex
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.63

GO:0008168

tr|T1EMG9|T1EMG9_HELRO
Uncharacterized protein
Search

DNALI1

0.79	LOW QUALITY PROTEIN: axonemal dynein light intermediate polypeptide 1

0.38

GO:0003341

cilium movement

0.85	GO:0045504	dynein heavy chain binding
0.45	GO:0003774	motor activity

0.82	GO:0030175	filopodium
0.79	GO:0005930	axoneme
0.47	GO:0030286	dynein complex
0.30	GO:0044425	membrane part

tr|T1EMH0|T1EMH0_HELRO
Mitogen-activated protein kinase
Search

0.56	Mitogen-activated protein kinase

0.78	GO:0000165	MAPK cascade
0.49	GO:0048082	regulation of adult chitin-containing cuticle pigmentation
0.48	GO:0038001	paracrine signaling
0.48	GO:0008340	determination of adult lifespan
0.47	GO:0071243	cellular response to arsenic-containing substance
0.47	GO:0050832	defense response to fungus
0.47	GO:0045793	positive regulation of cell size
0.47	GO:0006970	response to osmotic stress
0.47	GO:0071276	cellular response to cadmium ion
0.46	GO:1902882	regulation of response to oxidative stress

0.80	GO:0004707	MAP kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0008134	transcription factor binding
0.33	GO:0004040	amidase activity
0.32	GO:0046872	metal ion binding

0.45	GO:0005622	intracellular
0.40	GO:0043227	membrane-bounded organelle
0.39	GO:0005935	cellular bud neck
0.37	GO:0005934	cellular bud tip
0.36	GO:0043332	mating projection tip
0.33	GO:0042597	periplasmic space
0.30	GO:0016020	membrane

0.80	EC:2.7.11.24	GO:0004707
0.80	KEGG:R00162	GO:0004707

tr|T1EMH1|T1EMH1_HELRO
Uncharacterized protein
Search

HMGB2

0.56	High mobility group box 2

0.58	GO:0002437	inflammatory response to antigenic stimulus
0.56	GO:0072091	regulation of stem cell proliferation
0.56	GO:0050830	defense response to Gram-positive bacterium
0.56	GO:0050829	defense response to Gram-negative bacterium
0.55	GO:0032496	response to lipopolysaccharide
0.53	GO:0050767	regulation of neurogenesis
0.52	GO:0045654	positive regulation of megakaryocyte differentiation
0.51	GO:0032392	DNA geometric change
0.51	GO:0045648	positive regulation of erythrocyte differentiation
0.51	GO:0032075	positive regulation of nuclease activity

0.63	GO:0008301	DNA binding, bending
0.60	GO:0000400	four-way junction DNA binding
0.56	GO:0001158	enhancer sequence-specific DNA binding
0.56	GO:0097100	supercoiled DNA binding
0.52	GO:0050786	RAGE receptor binding
0.51	GO:0042056	chemoattractant activity
0.50	GO:0008134	transcription factor binding
0.46	GO:0003684	damaged DNA binding
0.45	GO:0019904	protein domain specific binding
0.43	GO:0003697	single-stranded DNA binding

0.61	GO:0005634	nucleus
0.51	GO:0005615	extracellular space
0.50	GO:0000785	chromatin
0.48	GO:0048471	perinuclear region of cytoplasm
0.48	GO:0070013	intracellular organelle lumen
0.47	GO:0000793	condensed chromosome
0.41	GO:0043234	protein complex
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0032440

tr|T1EMH2|T1EMH2_HELRO
Uncharacterized protein
Search

0.71	Caltractin

0.43	GO:0031023	microtubule organizing center organization
0.41	GO:0007049	cell cycle
0.40	GO:0034605	cellular response to heat
0.39	GO:0022607	cellular component assembly
0.39	GO:0032465	regulation of cytokinesis
0.38	GO:0006289	nucleotide-excision repair
0.37	GO:0007283	spermatogenesis
0.37	GO:0051301	cell division
0.35	GO:0044782	cilium organization
0.35	GO:0051640	organelle localization

0.70	GO:0005509	calcium ion binding
0.46	GO:0032795	heterotrimeric G-protein binding
0.43	GO:0031683	G-protein beta/gamma-subunit complex binding
0.41	GO:0008017	microtubule binding
0.34	GO:0005200	structural constituent of cytoskeleton
0.34	GO:0042802	identical protein binding
0.33	GO:0004386	helicase activity

0.50	GO:0044450	microtubule organizing center part
0.48	GO:0005813	centrosome
0.46	GO:0000922	spindle pole
0.44	GO:0032391	photoreceptor connecting cilium
0.42	GO:0071942	XPC complex
0.39	GO:0005816	spindle pole body
0.38	GO:0036064	ciliary basal body
0.35	GO:0000111	nucleotide-excision repair factor 2 complex
0.34	GO:0070390	transcription export complex 2
0.34	GO:0030008	TRAPP complex

tr|T1EMH3|T1EMH3_HELRO
Ubiquitin-fold modifier-conjugating enzyme 1
Search

UFC1

0.89	Ubiquitin-fold modifier-conjugating enzyme 1

0.86	GO:0071569	protein ufmylation
0.67	GO:0034976	response to endoplasmic reticulum stress
0.39	GO:0016579	protein deubiquitination
0.39	GO:0006511	ubiquitin-dependent protein catabolic process
0.36	GO:0042157	lipoprotein metabolic process
0.36	GO:0006869	lipid transport

0.87	GO:0071568	UFM1 transferase activity
0.39	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.35	GO:0008289	lipid binding
0.35	GO:0005515	protein binding

0.43	GO:0005737	cytoplasm
0.41	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.39

EC:3.4.19.12

GO:0036459

tr|T1EMH4|T1EMH4_HELRO
V-type proton ATPase subunit F
Search

0.72	V-type proton ATPase subunit F

0.76	GO:0015991	ATP hydrolysis coupled proton transport
0.46	GO:1901207	regulation of heart looping
0.46	GO:0060036	notochord cell vacuolation
0.45	GO:0070121	Kupffer's vesicle development
0.45	GO:1902017	regulation of cilium assembly
0.44	GO:0060041	retina development in camera-type eye
0.42	GO:0042127	regulation of cell proliferation
0.35	GO:0090383	phagosome acidification
0.35	GO:0033572	transferrin transport
0.34	GO:0008286	insulin receptor signaling pathway

0.81	GO:0046961	proton-transporting ATPase activity, rotational mechanism
0.34	GO:0042624	ATPase activity, uncoupled
0.33	GO:0005509	calcium ion binding
0.33	GO:0005515	protein binding

0.81	GO:0033180	proton-transporting V-type ATPase, V1 domain
0.45	GO:0016471	vacuolar proton-transporting V-type ATPase complex
0.37	GO:0005886	plasma membrane
0.36	GO:0070062	extracellular exosome
0.33	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

tr|T1EMH5|T1EMH5_HELRO
Uncharacterized protein
Search

EXOC3

0.68	Exocyst complex component

0.77	GO:0006887	exocytosis
0.48	GO:0051601	exocyst localization
0.35	GO:0015031	protein transport

0.49	GO:0045296	cadherin binding
0.45	GO:0000149	SNARE binding

0.79	GO:0000145	exocyst
0.37	GO:0030426	growth cone
0.37	GO:0030496	midbody
0.36	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0030667	secretory granule membrane
0.35	GO:0005794	Golgi apparatus
0.33	GO:0005829	cytosol

tr|T1EMH6|T1EMH6_HELRO
tRNA (guanine(26)-N(2))-dimethyltransferase
Search

0.74	Probable N2,N2-dimethylguanosine tRNA methyltransferase

0.74	GO:0030488	tRNA methylation
0.34	GO:0055114	oxidation-reduction process

0.84	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity
0.69	GO:0000049	tRNA binding
0.35	GO:0046872	metal ion binding
0.35	GO:0016491	oxidoreductase activity

0.37	GO:0005634	nucleus
0.37	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.84

GO:0004809

tr|T1EMH7|T1EMH7_HELRO
Uncharacterized protein
Search

TTC5

0.43	Tetratricopeptide repeat protein 5

0.69	GO:0045944	positive regulation of transcription by RNA polymerase II
0.41	GO:1901796	regulation of signal transduction by p53 class mediator
0.40	GO:0006281	DNA repair

0.71	GO:0003682	chromatin binding
0.52	GO:0003677	DNA binding
0.37	GO:0043531	ADP binding
0.37	GO:0005515	protein binding

0.68	GO:0005654	nucleoplasm
0.46	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1EMH8|T1EMH8_HELRO
Uncharacterized protein
Search

NDUFV2

0.84	NADH-ubiquinone dehydrogenase

0.53	GO:0055114	oxidation-reduction process
0.49	GO:0006511	ubiquitin-dependent protein catabolic process
0.47	GO:0007166	cell surface receptor signaling pathway
0.40	GO:0048738	cardiac muscle tissue development
0.40	GO:0006119	oxidative phosphorylation
0.39	GO:0007399	nervous system development
0.34	GO:0032981	mitochondrial respiratory chain complex I assembly
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process

0.65	GO:0051537	2 iron, 2 sulfur cluster binding
0.54	GO:0016491	oxidoreductase activity
0.52	GO:0031625	ubiquitin protein ligase binding
0.50	GO:0046872	metal ion binding
0.46	GO:0004888	transmembrane signaling receptor activity
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0003735	structural constituent of ribosome

0.45	GO:0005747	mitochondrial respiratory chain complex I
0.45	GO:0045272	plasma membrane respiratory chain complex I
0.35	GO:0043209	myelin sheath
0.32	GO:0005634	nucleus
0.32	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.54

GO:0016491

tr|T1EMH9|T1EMH9_HELRO
Uncharacterized protein
Search

tr|T1EMI0|T1EMI0_HELRO
Uncharacterized protein
Search

NOP56

0.92	NOP56 ribonucleoprotein homolog

0.59	GO:0007507	heart development
0.50	GO:0000154	rRNA modification

0.70	GO:1990226	histone methyltransferase binding
0.68	GO:0030515	snoRNA binding
0.64	GO:0045296	cadherin binding

0.71	GO:0070761	pre-snoRNP complex
0.66	GO:0005732	small nucleolar ribonucleoprotein complex
0.65	GO:0001650	fibrillar center
0.53	GO:0032040	small-subunit processome
0.50	GO:0019013	viral nucleocapsid
0.30	GO:0016020	membrane

tr|T1EMI1|T1EMI1_HELRO
Uncharacterized protein
Search

CTSF

0.37	Cysteine proteinase cathepsin F

0.70	GO:0010951	negative regulation of endopeptidase activity
0.61	GO:0006508	proteolysis
0.36	GO:0044257	cellular protein catabolic process
0.34	GO:0016567	protein ubiquitination

0.76	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.72	GO:0008234	cysteine-type peptidase activity
0.35	GO:0004175	endopeptidase activity
0.34	GO:0004842	ubiquitin-protein transferase activity
0.32	GO:0046872	metal ion binding

0.37	GO:0005764	lysosome
0.37	GO:0005615	extracellular space
0.30	GO:0016020	membrane

0.72	EC:3.4	GO:0008234
0.34	KEGG:R03876	GO:0004842

tr|T1EMI2|T1EMI2_HELRO
Uncharacterized protein
Search

NELFCD

0.93	Negative elongation factor D

0.72	GO:0045892	negative regulation of transcription, DNA-templated
0.56	GO:0006414	translational elongation
0.34	GO:0006351	transcription, DNA-templated
0.34	GO:0050434	positive regulation of viral transcription
0.34	GO:0034243	regulation of transcription elongation from RNA polymerase II promoter
0.33	GO:0006457	protein folding

0.57	GO:0003746	translation elongation factor activity
0.34	GO:0005515	protein binding
0.33	GO:0008270	zinc ion binding

0.61	GO:0005634	nucleus
0.36	GO:0031974	membrane-enclosed lumen
0.35	GO:0043234	protein complex
0.35	GO:0005703	polytene chromosome puff
0.34	GO:0005705	polytene chromosome interband
0.34	GO:0017053	transcriptional repressor complex
0.30	GO:0031224	intrinsic component of membrane

tr|T1EMI3|T1EMI3_HELRO
Exocyst complex component
Search

EXOC6B

0.78	Exocyst complex component

0.80	GO:0006904	vesicle docking involved in exocytosis
0.33	GO:0015031	protein transport
0.32	GO:0055114	oxidation-reduction process

0.34	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.33	GO:0005515	protein binding
0.33	GO:0020037	heme binding
0.33	GO:0005506	iron ion binding

0.78

GO:0000145

exocyst

0.34

EC:1.14

GO:0016705

tr|T1EMI4|T1EMI4_HELRO
Eukaryotic translation initiation factor 3 subunit B
Search

EIF3B

0.69	Eukaryotic translation initiation factor 3 subunit B

0.74	GO:0001731	formation of translation preinitiation complex
0.73	GO:0006446	regulation of translational initiation
0.50	GO:0075525	viral translational termination-reinitiation
0.50	GO:0075522	IRES-dependent viral translational initiation
0.37	GO:0003313	heart rudiment development
0.36	GO:0014032	neural crest cell development
0.32	GO:2001141	regulation of RNA biosynthetic process

0.83	GO:0031369	translation initiation factor binding
0.72	GO:0003743	translation initiation factor activity
0.34	GO:0032947	protein complex scaffold activity
0.33	GO:0046872	metal ion binding

0.78	GO:0005852	eukaryotic translation initiation factor 3 complex
0.74	GO:0016282	eukaryotic 43S preinitiation complex
0.74	GO:0033290	eukaryotic 48S preinitiation complex
0.34	GO:0070062	extracellular exosome
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

tr|T1EMI5|T1EMI5_HELRO
Uncharacterized protein
Search

0.50	Brefeldin A-inhibited guanine nucleotide-exchange protein 1

0.81	GO:0032012	regulation of ARF protein signal transduction
0.66	GO:0065009	regulation of molecular function
0.40	GO:0016192	vesicle-mediated transport
0.37	GO:1904801	positive regulation of neuron remodeling
0.36	GO:0061951	establishment of protein localization to plasma membrane
0.36	GO:0045807	positive regulation of endocytosis
0.35	GO:0006396	RNA processing
0.34	GO:0015031	protein transport
0.34	GO:0006468	protein phosphorylation

0.82	GO:0005086	ARF guanyl-nucleotide exchange factor activity
0.35	GO:0031267	small GTPase binding
0.34	GO:0004672	protein kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.42

GO:0005802

trans-Golgi network

tr|T1EMI6|T1EMI6_HELRO
Uncharacterized protein
Search

0.79	GO:0006885	regulation of pH
0.77	GO:0035725	sodium ion transmembrane transport
0.63	GO:1902600	hydrogen ion transmembrane transport
0.40	GO:0098659	inorganic cation import across plasma membrane
0.39	GO:0030004	cellular monovalent inorganic cation homeostasis
0.38	GO:0071805	potassium ion transmembrane transport
0.34	GO:0017182	peptidyl-diphthamide metabolic process
0.34	GO:1900247	regulation of cytoplasmic translational elongation
0.32	GO:0009058	biosynthetic process

0.82	GO:0015385	sodium:proton antiporter activity
0.40	GO:0015386	potassium:proton antiporter activity

0.38	GO:0005794	Golgi apparatus
0.35	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1EMI7|T1EMI7_HELRO
Uncharacterized protein
Search

ACTR6

0.88	ARP6 actin-related protein 6 homolog (Yeast)

0.78	GO:0006338	chromatin remodeling
0.33	GO:0006348	chromatin silencing at telomere
0.33	GO:0034728	nucleosome organization
0.33	GO:0016569	covalent chromatin modification
0.32	GO:0006351	transcription, DNA-templated

0.33

GO:0005515

protein binding

0.61	GO:0005634	nucleus
0.35	GO:0005856	cytoskeleton
0.34	GO:0000785	chromatin
0.33	GO:0000781	chromosome, telomeric region
0.33	GO:0005737	cytoplasm
0.32	GO:0031974	membrane-enclosed lumen
0.32	GO:1904949	ATPase complex
0.30	GO:0016020	membrane

tr|T1EMI8|T1EMI8_HELRO
Uncharacterized protein
Search

0.56	Molecular chaperone HtpG

0.69	GO:0006457	protein folding
0.62	GO:0006950	response to stress
0.48	GO:0009266	response to temperature stimulus
0.48	GO:0046677	response to antibiotic
0.37	GO:1905323	telomerase holoenzyme complex assembly
0.37	GO:0017038	protein import
0.36	GO:0072594	establishment of protein localization to organelle
0.36	GO:0019094	pole plasm mRNA localization
0.36	GO:0051973	positive regulation of telomerase activity
0.36	GO:0010529	negative regulation of transposition

0.71	GO:0051082	unfolded protein binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0030911	TPR domain binding
0.37	GO:0030235	nitric-oxide synthase regulator activity
0.36	GO:0070182	DNA polymerase binding
0.36	GO:0097110	scaffold protein binding
0.36	GO:0097718	disordered domain specific binding

0.43	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm
0.36	GO:0005705	polytene chromosome interband
0.36	GO:0032587	ruffle membrane
0.36	GO:0043209	myelin sheath
0.35	GO:0005813	centrosome
0.34	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.34

EC:3.6.1.3

GO:0016887

tr|T1EMI9|T1EMI9_HELRO
Uncharacterized protein
Search

RPL13A

0.68	Ribosomal protein L13

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.48	GO:1901194	negative regulation of formation of translation preinitiation complex
0.43	GO:0071346	cellular response to interferon-gamma
0.38	GO:0010469	regulation of receptor activity
0.38	GO:0048246	macrophage chemotaxis
0.37	GO:0060425	lung morphogenesis
0.37	GO:0032496	response to lipopolysaccharide

0.64	GO:0003735	structural constituent of ribosome
0.44	GO:0003729	mRNA binding
0.39	GO:0005125	cytokine activity
0.34	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.34	GO:0035091	phosphatidylinositol binding

0.71	GO:0015934	large ribosomal subunit
0.47	GO:0097452	GAIT complex
0.44	GO:0022626	cytosolic ribosome
0.36	GO:0005925	focal adhesion
0.35	GO:0005730	nucleolus
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:1.2.1

GO:0016620

tr|T1EMJ0|T1EMJ0_HELRO
Uncharacterized protein
Search

0.49	Diadenosine and diphosphoinositol polyphosphate phosphohydrolase

0.45	GO:0046626	regulation of insulin receptor signaling pathway
0.45	GO:0043647	inositol phosphate metabolic process
0.44	GO:0055088	lipid homeostasis
0.44	GO:0042593	glucose homeostasis
0.43	GO:0042594	response to starvation
0.40	GO:1901909	diadenosine hexaphosphate catabolic process
0.40	GO:1901907	diadenosine pentaphosphate catabolic process
0.40	GO:1901910	adenosine 5'-(hexahydrogen pentaphosphate) metabolic process
0.39	GO:0032446	protein modification by small protein conjugation
0.39	GO:0009169	purine ribonucleoside monophosphate catabolic process

0.50	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity
0.40	GO:0052848	inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity
0.40	GO:0052844	inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity
0.40	GO:0052845	inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity
0.40	GO:0052846	inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity
0.40	GO:0052847	inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity
0.40	GO:0052840	inositol diphosphate tetrakisphosphate diphosphatase activity
0.40	GO:0052843	inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity
0.40	GO:0034431	bis(5'-adenosyl)-hexaphosphatase activity
0.40	GO:0034432	bis(5'-adenosyl)-pentaphosphatase activity

0.41	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm
0.34	GO:0031248	protein acetyltransferase complex
0.33	GO:0005700	polytene chromosome
0.33	GO:0070013	intracellular organelle lumen
0.33	GO:0043234	protein complex
0.33	GO:0005856	cytoskeleton
0.32	GO:0044446	intracellular organelle part
0.32	GO:0012505	endomembrane system
0.32	GO:0030529	intracellular ribonucleoprotein complex

0.50	EC:3.6.1.52	GO:0008486
0.50	KEGG:R05777	GO:0008486

tr|T1EMJ1|T1EMJ1_HELRO
Protein Wnt
Search

0.77	GO:0016055	Wnt signaling pathway
0.70	GO:0007275	multicellular organism development
0.44	GO:0045165	cell fate commitment
0.40	GO:0009653	anatomical structure morphogenesis
0.38	GO:0009888	tissue development
0.38	GO:0050673	epithelial cell proliferation
0.38	GO:0031099	regeneration
0.37	GO:0042060	wound healing
0.37	GO:0048589	developmental growth
0.36	GO:1904888	cranial skeletal system development

0.73	GO:0005102	receptor binding
0.34	GO:0030545	receptor regulator activity
0.34	GO:0004559	alpha-mannosidase activity
0.33	GO:0030246	carbohydrate binding
0.32	GO:0046872	metal ion binding

0.75	GO:0005578	proteinaceous extracellular matrix
0.42	GO:0005615	extracellular space
0.30	GO:0005623	cell
0.30	GO:0016020	membrane

0.34

EC:3.2.1.24

GO:0004559

tr|T1EMJ2|T1EMJ2_HELRO
Uncharacterized protein
Search

DERA

0.49	deoxyribose-phosphate aldolase

0.78	GO:0009264	deoxyribonucleotide catabolic process
0.60	GO:0046386	deoxyribose phosphate catabolic process
0.50	GO:0046121	deoxyribonucleoside catabolic process
0.41	GO:0016052	carbohydrate catabolic process
0.34	GO:0043312	neutrophil degranulation
0.33	GO:0006098	pentose-phosphate shunt
0.32	GO:0055114	oxidation-reduction process

0.80	GO:0004139	deoxyribose-phosphate aldolase activity
0.33	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

0.49	GO:0005737	cytoplasm
0.40	GO:0005634	nucleus
0.35	GO:0070062	extracellular exosome
0.34	GO:0031983	vesicle lumen
0.33	GO:0097708	intracellular vesicle
0.33	GO:0012505	endomembrane system
0.33	GO:0070013	intracellular organelle lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.80	EC:4.1.2.4	GO:0004139
0.80	KEGG:R01066	GO:0004139

tr|T1EMJ3|T1EMJ3_HELRO
Uncharacterized protein
Search

0.43	ATP dependent DNA ligase region

0.80	GO:0051103	DNA ligation involved in DNA repair
0.67	GO:0071897	DNA biosynthetic process
0.65	GO:0006310	DNA recombination
0.65	GO:0006260	DNA replication
0.43	GO:0022616	DNA strand elongation
0.42	GO:0006284	base-excision repair
0.42	GO:1903047	mitotic cell cycle process
0.37	GO:0016070	RNA metabolic process
0.35	GO:0006297	nucleotide-excision repair, DNA gap filling
0.34	GO:0042542	response to hydrogen peroxide

0.78	GO:0003910	DNA ligase (ATP) activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0003677	DNA binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0019001	guanyl nucleotide binding
0.33	GO:0046872	metal ion binding
0.33	GO:0003700	DNA binding transcription factor activity

0.41	GO:0005654	nucleoplasm
0.38	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.78

EC:6.5.1.1

GO:0003910

tr|T1EMJ4|T1EMJ4_HELRO
Uncharacterized protein
Search

ATP5D

0.43	Mitochondrial ATP synthase subunit delta

0.69	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.69	GO:0006754	ATP biosynthetic process
0.67	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.35	GO:0042407	cristae formation
0.35	GO:0046688	response to copper ion
0.34	GO:0006839	mitochondrial transport
0.34	GO:0046907	intracellular transport
0.33	GO:0006119	oxidative phosphorylation

0.70	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism
0.36	GO:0047624	adenosine-tetraphosphatase activity
0.34	GO:0043531	ADP binding
0.34	GO:0032403	protein complex binding
0.32	GO:0005524	ATP binding

0.70	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)
0.50	GO:0005753	mitochondrial proton-transporting ATP synthase complex
0.34	GO:0005759	mitochondrial matrix
0.30	GO:0016021	integral component of membrane

0.36

EC:3.6.1.14

GO:0047624

tr|T1EMJ5|T1EMJ5_HELRO
Uncharacterized protein
Search

GOT1

0.47	Aspartate aminotransferase

0.60	GO:0006520	cellular amino acid metabolic process
0.52	GO:0006114	glycerol biosynthetic process
0.50	GO:0055089	fatty acid homeostasis
0.49	GO:0051384	response to glucocorticoid
0.49	GO:0032869	cellular response to insulin stimulus
0.48	GO:0006103	2-oxoglutarate metabolic process
0.48	GO:0007219	Notch signaling pathway
0.47	GO:0043650	dicarboxylic acid biosynthetic process
0.47	GO:0006107	oxaloacetate metabolic process
0.47	GO:0043649	dicarboxylic acid catabolic process

0.78	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity
0.74	GO:0070546	L-phenylalanine aminotransferase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.47	GO:0004609	phosphatidylserine decarboxylase activity
0.43	GO:0047801	L-cysteine:2-oxoglutarate aminotransferase activity
0.37	GO:0046872	metal ion binding
0.35	GO:0031406	carboxylic acid binding
0.32	GO:0003723	RNA binding
0.32	GO:0016491	oxidoreductase activity
0.32	GO:0016787	hydrolase activity

0.46	GO:0005829	cytosol
0.44	GO:0005654	nucleoplasm
0.39	GO:0005777	peroxisome
0.37	GO:0005739	mitochondrion
0.37	GO:0043679	axon terminus
0.36	GO:0005764	lysosome
0.35	GO:0070062	extracellular exosome
0.33	GO:0000178	exosome (RNase complex)

0.78	EC:2.6.1.1	GO:0004069
0.78	KEGG:R00355	GO:0004069

tr|T1EMJ6|T1EMJ6_HELRO
Uncharacterized protein
Search

HDDC3

0.61	Hd domain-containing protein 3

0.38	GO:0009159	deoxyribonucleoside monophosphate catabolic process
0.36	GO:0006904	vesicle docking involved in exocytosis
0.35	GO:0006783	heme biosynthetic process
0.35	GO:0032259	methylation
0.33	GO:0036211	protein modification process
0.33	GO:0044267	cellular protein metabolic process

0.51	GO:0016787	hydrolase activity
0.39	GO:0050144	nucleoside deoxyribosyltransferase activity
0.37	GO:0008728	GTP diphosphokinase activity
0.36	GO:0046872	metal ion binding
0.36	GO:0004325	ferrochelatase activity
0.35	GO:0008168	methyltransferase activity
0.34	GO:0005515	protein binding
0.33	GO:0003676	nucleic acid binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding

0.51	EC:3	GO:0016787
0.36	KEGG:R00310	GO:0004325

tr|T1EMJ7|T1EMJ7_HELRO
Uncharacterized protein
Search

0.69	Putative rna-binding protein etr-3 rrm superfamily

0.53	GO:0014881	regulation of myofibril size
0.53	GO:0007319	negative regulation of oskar mRNA translation
0.52	GO:0036099	female germ-line stem cell population maintenance
0.52	GO:0031536	positive regulation of exit from mitosis
0.51	GO:2000738	positive regulation of stem cell differentiation
0.50	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.50	GO:0045214	sarcomere organization
0.48	GO:0048477	oogenesis
0.37	GO:0032224	positive regulation of synaptic transmission, cholinergic
0.37	GO:0032230	positive regulation of synaptic transmission, GABAergic

0.59	GO:0003723	RNA binding
0.37	GO:0005515	protein binding
0.36	GO:0004747	ribokinase activity

0.50	GO:0043186	P granule
0.48	GO:0016604	nuclear body
0.48	GO:0031965	nuclear membrane
0.30	GO:0031224	intrinsic component of membrane

0.36

EC:2.7.1.15

GO:0004747

tr|T1EMJ8|T1EMJ8_HELRO
Uncharacterized protein
Search

0.55	Large neutral amino acids transporter small subunit

0.55	GO:0055085	transmembrane transport
0.47	GO:0000821	regulation of arginine metabolic process
0.46	GO:0006865	amino acid transport
0.38	GO:0014005	microglia development
0.37	GO:0006812	cation transport
0.34	GO:0008063	Toll signaling pathway
0.34	GO:0007623	circadian rhythm
0.33	GO:0006397	mRNA processing

0.57	GO:0022857	transmembrane transporter activity
0.32	GO:0003723	RNA binding

0.40	GO:0005887	integral component of plasma membrane
0.35	GO:0016323	basolateral plasma membrane
0.33	GO:0043231	intracellular membrane-bounded organelle
0.33	GO:0005829	cytosol
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0044446	intracellular organelle part

tr|T1EMJ9|T1EMJ9_HELRO
Uncharacterized protein
Search

PRKACA

0.72	cAMP-dependent protein kinase catalytic subunit alpha

0.63	GO:0006468	protein phosphorylation
0.49	GO:0071374	cellular response to parathyroid hormone stimulus
0.49	GO:1901621	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
0.49	GO:2000810	regulation of bicellular tight junction assembly
0.48	GO:0048240	sperm capacitation
0.48	GO:0071158	positive regulation of cell cycle arrest
0.47	GO:0034605	cellular response to heat
0.47	GO:0071333	cellular response to glucose stimulus
0.47	GO:0018209	peptidyl-serine modification
0.47	GO:0046827	positive regulation of protein export from nucleus

0.69	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.49	GO:0034237	protein kinase A regulatory subunit binding
0.46	GO:0004712	protein serine/threonine/tyrosine kinase activity
0.45	GO:0031625	ubiquitin protein ligase binding
0.45	GO:0019901	protein kinase binding
0.44	GO:0019904	protein domain specific binding

0.49	GO:0045171	intercellular bridge
0.49	GO:0005952	cAMP-dependent protein kinase complex
0.48	GO:0036126	sperm flagellum
0.48	GO:0001669	acrosomal vesicle
0.48	GO:0097546	ciliary base
0.47	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0043197	dendritic spine
0.47	GO:0044853	plasma membrane raft
0.47	GO:0031594	neuromuscular junction
0.46	GO:0005930	axoneme

0.69

GO:0004674

tr|T1EMK0|T1EMK0_HELRO
Uncharacterized protein
Search

ACADL

0.95	Acyl-CoA dehydrogenase long chain

0.85	GO:0042758	long-chain fatty acid catabolic process
0.53	GO:0055114	oxidation-reduction process

0.86	GO:0004466	long-chain-acyl-CoA dehydrogenase activity
0.66	GO:0050660	flavin adenine dinucleotide binding

0.86

EC:1.3.99.13

GO:0004466

tr|T1EMK1|T1EMK1_HELRO
DNA-directed RNA polymerase subunit beta
Search

0.34	DNA-directed RNA polymerase subunit beta

0.58	GO:0097659	nucleic acid-templated transcription
0.54	GO:0010467	gene expression
0.53	GO:0034645	cellular macromolecule biosynthetic process

0.70	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.65	GO:0001882	nucleoside binding
0.55	GO:0003677	DNA binding

0.34	GO:0005665	DNA-directed RNA polymerase II, core complex
0.30	GO:0031224	intrinsic component of membrane

0.70

GO:0003899

tr|T1EMK2|T1EMK2_HELRO
Uncharacterized protein
Search

tr|T1EMK3|T1EMK3_HELRO
Endonuclease III homolog
Search

0.72	Endonuclease III homolog

0.81	GO:0006285	base-excision repair, AP site formation
0.54	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.43	GO:0006289	nucleotide-excision repair
0.39	GO:0009223	pyrimidine deoxyribonucleotide catabolic process
0.38	GO:0070301	cellular response to hydrogen peroxide
0.36	GO:0006304	DNA modification

0.80	GO:0000703	oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity
0.74	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity
0.64	GO:0051539	4 iron, 4 sulfur cluster binding
0.54	GO:0004519	endonuclease activity
0.54	GO:0003677	DNA binding
0.52	GO:0046872	metal ion binding

0.59	GO:0005634	nucleus
0.55	GO:0005739	mitochondrion
0.35	GO:0042644	chloroplast nucleoid
0.30	GO:0016020	membrane

0.74

EC:4.2.99.18

GO:0003906

tr|T1EMK4|T1EMK4_HELRO
Uncharacterized protein
Search

0.41	Acetyl-CoA acetyltransferase PhbA

0.39	GO:0072329	monocarboxylic acid catabolic process
0.39	GO:0019395	fatty acid oxidation
0.38	GO:0044242	cellular lipid catabolic process
0.36	GO:0019614	catechol-containing compound catabolic process
0.36	GO:0046278	3,4-dihydroxybenzoate metabolic process
0.35	GO:0042737	drug catabolic process

0.64

GO:0016747

transferase activity, transferring acyl groups other than amino-acyl groups

0.35	GO:0005739	mitochondrion
0.34	GO:0005730	nucleolus
0.33	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.64

GO:0016747

tr|T1EMK5|T1EMK5_HELRO
Uncharacterized protein
Search

0.49	GO:0006886	intracellular protein transport
0.42	GO:1903506	regulation of nucleic acid-templated transcription
0.42	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.42	GO:0010468	regulation of gene expression
0.41	GO:0006518	peptide metabolic process
0.40	GO:0043604	amide biosynthetic process
0.40	GO:0044267	cellular protein metabolic process
0.39	GO:0010467	gene expression
0.38	GO:1901566	organonitrogen compound biosynthetic process
0.38	GO:0009059	macromolecule biosynthetic process

0.52	GO:0035091	phosphatidylinositol binding
0.44	GO:0003700	DNA binding transcription factor activity
0.41	GO:0003723	RNA binding
0.40	GO:0003735	structural constituent of ribosome
0.40	GO:0004819	glutamine-tRNA ligase activity
0.38	GO:0005272	sodium channel activity
0.38	GO:0016817	hydrolase activity, acting on acid anhydrides
0.37	GO:0008234	cysteine-type peptidase activity
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding

0.42	GO:0015935	small ribosomal subunit
0.35	GO:0005769	early endosome
0.34	GO:0005634	nucleus
0.33	GO:0005694	chromosome
0.33	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.40

EC:6.1.1.18

GO:0004819

tr|T1EMK6|T1EMK6_HELRO
Uncharacterized protein
Search

ABHD11

0.18	Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex

0.33

GO:0008615

pyridoxine biosynthetic process

0.46	GO:0016787	hydrolase activity
0.36	GO:0016746	transferase activity, transferring acyl groups
0.33	GO:0033856	pyridoxine 5'-phosphate synthase activity

0.33	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.46	EC:3	GO:0016787
0.33	KEGG:R05838	GO:0033856

tr|T1EMK7|T1EMK7_HELRO
Uncharacterized protein
Search

tr|T1EMK8|T1EMK8_HELRO
Uncharacterized protein
Search

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0035295	tube development
0.52	GO:0048731	system development
0.49	GO:0009880	embryonic pattern specification
0.47	GO:0060429	epithelium development
0.44	GO:0051253	negative regulation of RNA metabolic process
0.44	GO:0010558	negative regulation of macromolecule biosynthetic process

0.66	GO:0046983	protein dimerization activity
0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0003677	DNA binding
0.40	GO:0001067	regulatory region nucleic acid binding

0.61	GO:0005634	nucleus
0.55	GO:0005667	transcription factor complex
0.43	GO:0043233	organelle lumen
0.41	GO:0005737	cytoplasm
0.40	GO:0044446	intracellular organelle part

tr|T1EMK9|T1EMK9_HELRO
Uncharacterized protein
Search

IFT80

0.91	Intraflagellar transport protein 80

0.59	GO:0060271	cilium assembly
0.57	GO:2000051	negative regulation of non-canonical Wnt signaling pathway
0.55	GO:0045880	positive regulation of smoothened signaling pathway
0.54	GO:0002062	chondrocyte differentiation
0.54	GO:0001649	osteoblast differentiation
0.54	GO:0060349	bone morphogenesis
0.54	GO:0050680	negative regulation of epithelial cell proliferation
0.53	GO:0007224	smoothened signaling pathway
0.41	GO:0090326	positive regulation of locomotion involved in locomotory behavior
0.41	GO:0060026	convergent extension

0.36	GO:0005198	structural molecule activity
0.35	GO:0004402	histone acetyltransferase activity
0.34	GO:0008270	zinc ion binding
0.34	GO:0005509	calcium ion binding

0.73	GO:0005929	cilium
0.58	GO:0030992	intraciliary transport particle B
0.55	GO:0005813	centrosome
0.40	GO:0120038	plasma membrane bounded cell projection part
0.34	GO:0033588	Elongator holoenzyme complex
0.33	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

0.35

GO:0004402

tr|T1EML0|T1EML0_HELRO
Uncharacterized protein
Search

YJBQ

0.49	Secondary thiamine-phosphate synthase enzyme

0.50	GO:0001731	formation of translation preinitiation complex
0.50	GO:0006446	regulation of translational initiation
0.45	GO:0016106	sesquiterpenoid biosynthetic process
0.43	GO:0015937	coenzyme A biosynthetic process
0.41	GO:0009767	photosynthetic electron transport chain
0.38	GO:0016310	phosphorylation

0.51	GO:0031369	translation initiation factor binding
0.47	GO:0003743	translation initiation factor activity
0.45	GO:0045482	trichodiene synthase activity
0.44	GO:0004140	dephospho-CoA kinase activity
0.42	GO:0016168	chlorophyll binding
0.37	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0008144	drug binding
0.37	GO:0016491	oxidoreductase activity
0.37	GO:0035639	purine ribonucleoside triphosphate binding

0.50	GO:0016282	eukaryotic 43S preinitiation complex
0.50	GO:0033290	eukaryotic 48S preinitiation complex
0.49	GO:0005852	eukaryotic translation initiation factor 3 complex
0.40	GO:0009521	photosystem
0.39	GO:0009507	chloroplast
0.30	GO:0016021	integral component of membrane

0.45	EC:4.2.3.6	GO:0045482
0.45	KEGG:R02306	GO:0045482

tr|T1EML1|T1EML1_HELRO
Uncharacterized protein
Search

IBA57

0.89	Transcription factor component of ccr4 transcriptional complex

0.48	GO:0031163	metallo-sulfur cluster assembly
0.46	GO:0051188	cofactor biosynthetic process
0.45	GO:0042168	heme metabolic process
0.45	GO:0006790	sulfur compound metabolic process
0.44	GO:0046148	pigment biosynthetic process
0.44	GO:0033014	tetrapyrrole biosynthetic process
0.42	GO:0051321	meiotic cell cycle
0.42	GO:0035023	regulation of Rho protein signal transduction
0.39	GO:0065009	regulation of molecular function
0.39	GO:0097428	protein maturation by iron-sulfur cluster transfer

0.45	GO:0016740	transferase activity
0.42	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.37	GO:0140096	catalytic activity, acting on a protein
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0043168	anion binding
0.36	GO:0008144	drug binding
0.36	GO:0098599	palmitoyl hydrolase activity
0.34	GO:0003723	RNA binding
0.34	GO:0051287	NAD binding
0.32	GO:0016491	oxidoreductase activity

0.50	GO:0005759	mitochondrial matrix
0.35	GO:0005922	connexin complex
0.30	GO:0031224	intrinsic component of membrane

0.45

GO:0016740

tr|T1EML2|T1EML2_HELRO
Uncharacterized protein
Search

tr|T1EML3|T1EML3_HELRO
DNA-directed RNA polymerase subunit
Search

0.22	DNA-directed RNA polymerase subunit

0.63	GO:0006366	transcription by RNA polymerase II
0.45	GO:2000543	positive regulation of gastrulation
0.44	GO:0009299	mRNA transcription
0.43	GO:0007369	gastrulation
0.42	GO:0009792	embryo development ending in birth or egg hatching
0.41	GO:0045893	positive regulation of transcription, DNA-templated
0.34	GO:0006298	mismatch repair
0.32	GO:0055114	oxidation-reduction process

0.70	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.55	GO:0003677	DNA binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0016491	oxidoreductase activity
0.32	GO:0046872	metal ion binding

0.67	GO:0005665	DNA-directed RNA polymerase II, core complex
0.43	GO:0035327	transcriptionally active chromatin

0.70

GO:0003899

tr|T1EML4|T1EML4_HELRO
Histone H2B
Search

tr|T1EML5|T1EML5_HELRO
Uncharacterized protein
Search

0.41	GO:0043412	macromolecule modification
0.41	GO:0000256	allantoin catabolic process
0.40	GO:0015031	protein transport
0.40	GO:0060255	regulation of macromolecule metabolic process
0.39	GO:0019538	protein metabolic process
0.39	GO:0050794	regulation of cellular process
0.39	GO:0051171	regulation of nitrogen compound metabolic process
0.39	GO:0080090	regulation of primary metabolic process
0.39	GO:0009889	regulation of biosynthetic process
0.39	GO:0006914	autophagy

0.41	GO:0004037	allantoicase activity
0.41	GO:0140096	catalytic activity, acting on a protein
0.40	GO:0003700	DNA binding transcription factor activity
0.39	GO:0009982	pseudouridine synthase activity
0.39	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.39	GO:0008536	Ran GTPase binding
0.39	GO:0016301	kinase activity
0.38	GO:0003723	RNA binding
0.38	GO:0046872	metal ion binding
0.38	GO:0030554	adenyl nucleotide binding

0.38	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm
0.35	GO:0030286	dynein complex
0.34	GO:0012505	endomembrane system
0.34	GO:0035770	ribonucleoprotein granule
0.34	GO:0030015	CCR4-NOT core complex
0.34	GO:0000785	chromatin
0.34	GO:0098588	bounding membrane of organelle
0.33	GO:0099023	tethering complex
0.33	GO:0031984	organelle subcompartment

0.41	EC:3.5.3.4	GO:0004037
0.41	KEGG:R02422	GO:0004037

tr|T1EML6|T1EML6_HELRO
Uncharacterized protein
Search

0.44	GO:0006030	chitin metabolic process
0.41	GO:0006413	translational initiation
0.39	GO:0044273	sulfur compound catabolic process
0.39	GO:0042219	cellular modified amino acid catabolic process
0.39	GO:0007165	signal transduction
0.38	GO:0198738	cell-cell signaling by wnt
0.38	GO:0030329	prenylcysteine metabolic process
0.37	GO:0006508	proteolysis
0.37	GO:0032501	multicellular organismal process
0.37	GO:0043171	peptide catabolic process

0.44	GO:0008061	chitin binding
0.42	GO:0003743	translation initiation factor activity
0.38	GO:0140096	catalytic activity, acting on a protein
0.38	GO:0001735	prenylcysteine oxidase activity
0.37	GO:0008270	zinc ion binding
0.37	GO:0016787	hydrolase activity
0.37	GO:0005515	protein binding
0.36	GO:0060089	molecular transducer activity
0.36	GO:0005540	hyaluronic acid binding
0.36	GO:0003677	DNA binding

0.44	GO:0005576	extracellular region
0.40	GO:0005634	nucleus
0.37	GO:0012505	endomembrane system
0.36	GO:0031967	organelle envelope
0.36	GO:0043234	protein complex
0.34	GO:0005856	cytoskeleton
0.34	GO:0031248	protein acetyltransferase complex
0.33	GO:0070013	intracellular organelle lumen
0.33	GO:0016324	apical plasma membrane
0.32	GO:0005737	cytoplasm

0.38

EC:1.8.3.5

GO:0001735

tr|T1EML7|T1EML7_HELRO
Uncharacterized protein
Search

0.43	GO:0006338	chromatin remodeling
0.40	GO:0033554	cellular response to stress
0.40	GO:0007018	microtubule-based movement
0.39	GO:0016070	RNA metabolic process
0.39	GO:0043412	macromolecule modification
0.39	GO:0044260	cellular macromolecule metabolic process
0.38	GO:0010467	gene expression
0.38	GO:0034654	nucleobase-containing compound biosynthetic process
0.37	GO:0051171	regulation of nitrogen compound metabolic process
0.37	GO:0060255	regulation of macromolecule metabolic process

0.41	GO:0003676	nucleic acid binding
0.40	GO:0017111	nucleoside-triphosphatase activity
0.38	GO:0046872	metal ion binding
0.37	GO:0140110	transcription regulator activity
0.37	GO:0140096	catalytic activity, acting on a protein
0.37	GO:0030554	adenyl nucleotide binding
0.36	GO:0032553	ribonucleotide binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity
0.36	GO:0008144	drug binding

0.43	GO:0031011	Ino80 complex
0.36	GO:0043234	protein complex
0.35	GO:0000932	P-body
0.35	GO:0044451	nucleoplasm part
0.34	GO:1990234	transferase complex
0.34	GO:0048475	coated membrane
0.33	GO:0005576	extracellular region
0.33	GO:1905369	endopeptidase complex
0.33	GO:0005840	ribosome
0.33	GO:1990391	DNA repair complex

0.40

EC:3.6.1.15

GO:0017111

tr|T1EML8|T1EML8_HELRO
Uncharacterized protein
Search

tr|T1EML9|T1EML9_HELRO
Uncharacterized protein
Search

tr|T1EMM0|T1EMM0_HELRO
Uncharacterized protein
Search

0.64	GO:0000723	telomere maintenance
0.58	GO:0032392	DNA geometric change
0.55	GO:0006310	DNA recombination
0.55	GO:0006281	DNA repair

0.64	GO:0004386	helicase activity
0.53	GO:0140097	catalytic activity, acting on DNA
0.53	GO:0030554	adenyl nucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0032555	purine ribonucleotide binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0003676	nucleic acid binding

tr|T1EMM1|T1EMM1_HELRO
Uncharacterized protein
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tr|T1EMM2|T1EMM2_HELRO
Uncharacterized protein
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tr|T1EMM3|T1EMM3_HELRO
Uncharacterized protein
Search

tr|T1EMM4|T1EMM4_HELRO
Uncharacterized protein
Search

tr|T1EMM5|T1EMM5_HELRO
Uncharacterized protein
Search

tr|T1EMM6|T1EMM6_HELRO
Uncharacterized protein
Search

0.49	GO:0006464	cellular protein modification process
0.44	GO:0016310	phosphorylation
0.44	GO:0055114	oxidation-reduction process
0.42	GO:0006629	lipid metabolic process

0.50	GO:0010181	FMN binding
0.47	GO:0140096	catalytic activity, acting on a protein
0.46	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.45	GO:0016301	kinase activity
0.44	GO:0016491	oxidoreductase activity
0.43	GO:0030554	adenyl nucleotide binding
0.42	GO:0008144	drug binding
0.42	GO:0032555	purine ribonucleotide binding
0.42	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0046872	metal ion binding

0.46

GO:0016773

tr|T1EMM7|T1EMM7_HELRO
Uncharacterized protein
Search

tr|T1EMM8|T1EMM8_HELRO
Uncharacterized protein
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tr|T1EMM9|T1EMM9_HELRO
Uncharacterized protein
Search

0.81	GO:0007160	cell-matrix adhesion
0.35	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.35	GO:0007339	binding of sperm to zona pellucida

0.50	GO:0005509	calcium ion binding
0.35	GO:0050840	extracellular matrix binding

0.34	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

tr|T1EMN0|T1EMN0_HELRO
Uncharacterized protein
Search

tr|T1EMN1|T1EMN1_HELRO
Uncharacterized protein
Search

tr|T1EMN2|T1EMN2_HELRO
Uncharacterized protein
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tr|T1EMN3|T1EMN3_HELRO
Uncharacterized protein
Search

0.51	GO:0006429	leucyl-tRNA aminoacylation
0.49	GO:0106074	aminoacyl-tRNA metabolism involved in translational fidelity
0.41	GO:0006468	protein phosphorylation
0.40	GO:0048193	Golgi vesicle transport
0.40	GO:0046907	intracellular transport
0.39	GO:0033036	macromolecule localization
0.39	GO:0018212	peptidyl-tyrosine modification
0.39	GO:0043085	positive regulation of catalytic activity
0.38	GO:0031156	regulation of sorocarp development
0.38	GO:0016071	mRNA metabolic process

0.52	GO:0004823	leucine-tRNA ligase activity
0.49	GO:0002161	aminoacyl-tRNA editing activity
0.43	GO:0030554	adenyl nucleotide binding
0.43	GO:0097367	carbohydrate derivative binding
0.43	GO:0008144	drug binding
0.43	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0140096	catalytic activity, acting on a protein
0.40	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.40	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.40	GO:0019899	enzyme binding

0.42	GO:0005634	nucleus
0.41	GO:0005737	cytoplasm
0.40	GO:0097708	intracellular vesicle
0.39	GO:0012505	endomembrane system
0.39	GO:0044446	intracellular organelle part
0.38	GO:0012506	vesicle membrane
0.38	GO:0098805	whole membrane
0.37	GO:0098588	bounding membrane of organelle
0.37	GO:0070013	intracellular organelle lumen
0.37	GO:0043234	protein complex

0.52	EC:6.1.1.4	GO:0004823
0.52	KEGG:R03657	GO:0004823

tr|T1EMN4|T1EMN4_HELRO
Uncharacterized protein
Search

tr|T1EMN5|T1EMN5_HELRO
Uncharacterized protein
Search

tr|T1EMN6|T1EMN6_HELRO
Uncharacterized protein
Search

tr|T1EMN7|T1EMN7_HELRO
Uncharacterized protein
Search

0.34	GO:0035556	intracellular signal transduction
0.34	GO:0006413	translational initiation
0.34	GO:0010951	negative regulation of endopeptidase activity
0.33	GO:0006508	proteolysis

0.51	GO:0003676	nucleic acid binding
0.37	GO:0046872	metal ion binding
0.34	GO:0004867	serine-type endopeptidase inhibitor activity
0.34	GO:0008234	cysteine-type peptidase activity

0.32	GO:0005622	intracellular
0.30	GO:0016020	membrane

0.34

GO:0008234

tr|T1EMN8|T1EMN8_HELRO
Uncharacterized protein
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tr|T1EMN9|T1EMN9_HELRO
Uncharacterized protein
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tr|T1EMP0|T1EMP0_HELRO
Uncharacterized protein
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tr|T1EMP1|T1EMP1_HELRO
Uncharacterized protein
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0.54

GO:0051568

histone H3-K4 methylation

0.55	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.50	GO:0003677	DNA binding
0.41	GO:0046872	metal ion binding

0.52

GO:0035097

histone methyltransferase complex

tr|T1EMP2|T1EMP2_HELRO
Uncharacterized protein
Search

tr|T1EMP3|T1EMP3_HELRO
Uncharacterized protein
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tr|T1EMP4|T1EMP4_HELRO
Uncharacterized protein
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tr|T1EMP5|T1EMP5_HELRO
Uncharacterized protein
Search

0.30

GO:0044425

membrane part

tr|T1EMP6|T1EMP6_HELRO
Uncharacterized protein
Search

tr|T1EMP7|T1EMP7_HELRO
Uncharacterized protein
Search

tr|T1EMP8|T1EMP8_HELRO
Uncharacterized protein
Search

tr|T1EMP9|T1EMP9_HELRO
Uncharacterized protein
Search

tr|T1EMQ0|T1EMQ0_HELRO
Uncharacterized protein
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tr|T1EMQ1|T1EMQ1_HELRO
Uncharacterized protein
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0.39	GO:0001945	lymph vessel development
0.34	GO:0006260	DNA replication
0.33	GO:0016310	phosphorylation
0.32	GO:0007155	cell adhesion

0.69	GO:0005509	calcium ion binding
0.39	GO:0003682	chromatin binding
0.33	GO:0016301	kinase activity
0.33	GO:0003677	DNA binding
0.32	GO:0030246	carbohydrate binding

0.38	GO:0005615	extracellular space
0.33	GO:0005634	nucleus
0.31	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1EMQ2|T1EMQ2_HELRO
Uncharacterized protein
Search

0.51	GO:0007219	Notch signaling pathway
0.47	GO:0030154	cell differentiation
0.47	GO:0007275	multicellular organism development
0.45	GO:0050793	regulation of developmental process
0.41	GO:0045967	negative regulation of growth rate
0.39	GO:0046849	bone remodeling
0.39	GO:0046579	positive regulation of Ras protein signal transduction
0.39	GO:0006355	regulation of transcription, DNA-templated
0.39	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.39	GO:0007050	cell cycle arrest

0.70	GO:0005509	calcium ion binding
0.42	GO:0004872	receptor activity
0.42	GO:0003682	chromatin binding
0.34	GO:0004175	endopeptidase activity
0.34	GO:0004871	signal transducer activity
0.34	GO:0005515	protein binding
0.34	GO:0030246	carbohydrate binding
0.34	GO:0008237	metallopeptidase activity
0.33	GO:0019828	aspartic-type endopeptidase inhibitor activity
0.33	GO:0070001	aspartic-type peptidase activity

0.41	GO:0005615	extracellular space
0.38	GO:0043235	receptor complex
0.38	GO:0009986	cell surface
0.37	GO:0033166	hyaline layer
0.36	GO:0005654	nucleoplasm
0.36	GO:0005887	integral component of plasma membrane
0.35	GO:0044420	extracellular matrix component
0.35	GO:0005902	microvillus
0.34	GO:0005913	cell-cell adherens junction
0.34	GO:0031410	cytoplasmic vesicle

0.33

GO:0032440

tr|T1EMQ3|T1EMQ3_HELRO
Uncharacterized protein
Search

tr|T1EMQ4|T1EMQ4_HELRO
Uncharacterized protein
Search

tr|T1EMQ5|T1EMQ5_HELRO
Uncharacterized protein
Search

0.76	GO:0048854	brain morphogenesis
0.72	GO:0007610	behavior
0.61	GO:0060292	long term synaptic depression
0.61	GO:0051968	positive regulation of synaptic transmission, glutamatergic
0.60	GO:1904717	regulation of AMPA glutamate receptor clustering
0.60	GO:0097117	guanylate kinase-associated protein clustering
0.59	GO:0021773	striatal medium spiny neuron differentiation
0.59	GO:0051835	positive regulation of synapse structural plasticity
0.59	GO:0060291	long-term synaptic potentiation
0.59	GO:0097114	NMDA glutamate receptor clustering

0.60	GO:0035255	ionotropic glutamate receptor binding
0.56	GO:0097110	scaffold protein binding
0.54	GO:0008022	protein C-terminus binding
0.38	GO:0004519	endonuclease activity
0.37	GO:0004672	protein kinase activity
0.35	GO:0030554	adenyl nucleotide binding
0.35	GO:0005216	ion channel activity
0.35	GO:0097367	carbohydrate derivative binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0008144	drug binding

0.58	GO:0044309	neuron spine
0.43	GO:0005883	neurofilament
0.43	GO:0001917	photoreceptor inner segment
0.43	GO:0008328	ionotropic glutamate receptor complex
0.43	GO:0001750	photoreceptor outer segment
0.42	GO:0030425	dendrite
0.42	GO:0045211	postsynaptic membrane
0.39	GO:0005576	extracellular region
0.35	GO:0005634	nucleus

tr|T1EMQ6|T1EMQ6_HELRO
Uncharacterized protein
Search

tr|T1EMQ7|T1EMQ7_HELRO
Uncharacterized protein
Search

0.53	GO:0000278	mitotic cell cycle
0.49	GO:0043666	regulation of phosphoprotein phosphatase activity
0.49	GO:0051301	cell division
0.46	GO:0035308	negative regulation of protein dephosphorylation
0.46	GO:0010923	negative regulation of phosphatase activity
0.45	GO:0045842	positive regulation of mitotic metaphase/anaphase transition
0.45	GO:0051457	maintenance of protein location in nucleus
0.44	GO:0044458	motile cilium assembly
0.41	GO:0007059	chromosome segregation
0.40	GO:0018279	protein N-linked glycosylation via asparagine

0.51	GO:0072542	protein phosphatase activator activity
0.47	GO:0004865	protein serine/threonine phosphatase inhibitor activity
0.37	GO:0016757	transferase activity, transferring glycosyl groups
0.36	GO:0005515	protein binding

0.49	GO:0008287	protein serine/threonine phosphatase complex
0.48	GO:0005929	cilium
0.41	GO:0005634	nucleus
0.39	GO:0044444	cytoplasmic part
0.38	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.37	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.37

GO:0016757

tr|T1EMQ8|T1EMQ8_HELRO
Uncharacterized protein
Search

tr|T1EMQ9|T1EMQ9_HELRO
Uncharacterized protein
Search

0.77	GO:0048010	vascular endothelial growth factor receptor signaling pathway
0.77	GO:0038084	vascular endothelial growth factor signaling pathway
0.62	GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway
0.61	GO:0010863	positive regulation of phospholipase C activity
0.61	GO:0002548	monocyte chemotaxis
0.61	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity
0.60	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling
0.58	GO:0045766	positive regulation of angiogenesis
0.57	GO:0006468	protein phosphorylation
0.57	GO:0043406	positive regulation of MAP kinase activity

0.77	GO:0005021	vascular endothelial growth factor-activated receptor activity
0.65	GO:0036332	placental growth factor-activated receptor activity
0.57	GO:0019838	growth factor binding
0.50	GO:0032559	adenyl ribonucleotide binding
0.50	GO:0008144	drug binding
0.50	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0042803	protein homodimerization activity

0.60	GO:0005887	integral component of plasma membrane
0.55	GO:0043235	receptor complex
0.53	GO:0015629	actin cytoskeleton
0.47	GO:0005768	endosome
0.46	GO:0005615	extracellular space
0.42	GO:0005634	nucleus

tr|T1EMR0|T1EMR0_HELRO
Uncharacterized protein
Search

tr|T1EMR1|T1EMR1_HELRO
Uncharacterized protein
Search

tr|T1EMR2|T1EMR2_HELRO
Uncharacterized protein
Search

0.40	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.40	GO:1903506	regulation of nucleic acid-templated transcription
0.40	GO:0010468	regulation of gene expression
0.39	GO:0005975	carbohydrate metabolic process

0.55	GO:0003723	RNA binding
0.42	GO:0003700	DNA binding transcription factor activity
0.40	GO:0016757	transferase activity, transferring glycosyl groups

0.39	GO:0005634	nucleus
0.30	GO:0044425	membrane part

0.40

GO:0016757

tr|T1EMR3|T1EMR3_HELRO
Uncharacterized protein
Search

tr|T1EMR4|T1EMR4_HELRO
Uncharacterized protein
Search

tr|T1EMR5|T1EMR5_HELRO
Uncharacterized protein
Search

tr|T1EMR6|T1EMR6_HELRO
Uncharacterized protein
Search

tr|T1EMR7|T1EMR7_HELRO
Uncharacterized protein
Search

tr|T1EMR8|T1EMR8_HELRO
Uncharacterized protein
Search

0.34	GO:0006461	protein complex assembly
0.34	GO:0006357	regulation of transcription by RNA polymerase II
0.34	GO:0007275	multicellular organism development
0.33	GO:0016310	phosphorylation

0.66	GO:0046983	protein dimerization activity
0.34	GO:0003676	nucleic acid binding
0.34	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.34	GO:0003779	actin binding
0.33	GO:0020037	heme binding
0.33	GO:0016301	kinase activity

0.34	GO:0005654	nucleoplasm
0.33	GO:0005739	mitochondrion
0.30	GO:0044425	membrane part

tr|T1EMR9|T1EMR9_HELRO
Uncharacterized protein
Search

tr|T1EMS0|T1EMS0_HELRO
Uncharacterized protein
Search

tr|T1EMS1|T1EMS1_HELRO
Uncharacterized protein
Search

tr|T1EMS2|T1EMS2_HELRO
Uncharacterized protein
Search

0.72	GO:0006470	protein dephosphorylation
0.42	GO:0001522	pseudouridine synthesis
0.38	GO:0016310	phosphorylation
0.37	GO:0031152	aggregation involved in sorocarp development
0.36	GO:1900424	regulation of defense response to bacterium
0.36	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.36	GO:0000188	inactivation of MAPK activity
0.34	GO:0008033	tRNA processing
0.33	GO:0010468	regulation of gene expression

0.79	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.63	GO:0004725	protein tyrosine phosphatase activity
0.42	GO:0009982	pseudouridine synthase activity
0.39	GO:0016301	kinase activity
0.39	GO:0003723	RNA binding
0.36	GO:0033549	MAP kinase phosphatase activity
0.36	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.34	GO:0005856	cytoskeleton
0.30	GO:0016020	membrane

0.79

GO:0008138

tr|T1EMS3|T1EMS3_HELRO
Uncharacterized protein
Search

tr|T1EMS4|T1EMS4_HELRO
Uncharacterized protein
Search

tr|T1EMS5|T1EMS5_HELRO
Uncharacterized protein
Search

tr|T1EMS6|T1EMS6_HELRO
Uncharacterized protein
Search

tr|T1EMS7|T1EMS7_HELRO
Uncharacterized protein
Search

tr|T1EMS8|T1EMS8_HELRO
Uncharacterized protein
Search

tr|T1EMS9|T1EMS9_HELRO
Uncharacterized protein
Search

0.55

GO:0003677

DNA binding

tr|T1EMT0|T1EMT0_HELRO
Uncharacterized protein
Search

MORN3

0.86	MORN repeat-containing protein 3

0.52	GO:0016310	phosphorylation
0.50	GO:0035082	axoneme assembly
0.50	GO:0007286	spermatid development
0.37	GO:0019538	protein metabolic process
0.37	GO:0051321	meiotic cell cycle
0.37	GO:0032259	methylation
0.36	GO:0043412	macromolecule modification
0.36	GO:0007018	microtubule-based movement
0.34	GO:0044260	cellular macromolecule metabolic process

0.54	GO:0016301	kinase activity
0.39	GO:0005515	protein binding
0.38	GO:0008234	cysteine-type peptidase activity
0.37	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.37	GO:0008168	methyltransferase activity
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0003777	microtubule motor activity
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0008270	zinc ion binding

0.53	GO:0001520	outer dense fiber
0.52	GO:0072687	meiotic spindle
0.48	GO:0000794	condensed nuclear chromosome
0.37	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.38

GO:0008234

tr|T1EMT1|T1EMT1_HELRO
Uncharacterized protein
Search

tr|T1EMT2|T1EMT2_HELRO
Uncharacterized protein
Search

tr|T1EMT3|T1EMT3_HELRO
Uncharacterized protein
Search

tr|T1EMT4|T1EMT4_HELRO
Uncharacterized protein
Search

0.74	GO:0007018	microtubule-based movement
0.40	GO:0030705	cytoskeleton-dependent intracellular transport
0.39	GO:0007411	axon guidance
0.37	GO:0007097	nuclear migration
0.36	GO:0051321	meiotic cell cycle
0.36	GO:0033036	macromolecule localization
0.36	GO:0000280	nuclear division
0.36	GO:0019953	sexual reproduction
0.36	GO:0022402	cell cycle process
0.36	GO:0000741	karyogamy

0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0016887	ATPase activity
0.34	GO:0046982	protein heterodimerization activity
0.32	GO:0003676	nucleic acid binding

0.58	GO:0005874	microtubule
0.41	GO:0005871	kinesin complex
0.36	GO:0005816	spindle pole body
0.36	GO:0043005	neuron projection
0.35	GO:0035253	ciliary rootlet
0.34	GO:0005635	nuclear envelope
0.34	GO:0045202	synapse
0.34	GO:0072686	mitotic spindle
0.33	GO:0005737	cytoplasm

0.38

EC:3.6.1.3

GO:0016887

tr|T1EMT5|T1EMT5_HELRO
Uncharacterized protein
Search

tr|T1EMT6|T1EMT6_HELRO
Uncharacterized protein
Search

tr|T1EMT7|T1EMT7_HELRO
Uncharacterized protein
Search

tr|T1EMT8|T1EMT8_HELRO
Uncharacterized protein
Search

tr|T1EMT9|T1EMT9_HELRO
Uncharacterized protein
Search

tr|T1EMU0|T1EMU0_HELRO
Uncharacterized protein
Search

0.51	Survival motor neuron protein

0.70	GO:0006397	mRNA processing
0.39	GO:0000904	cell morphogenesis involved in differentiation
0.39	GO:0007019	microtubule depolymerization
0.39	GO:0033120	positive regulation of RNA splicing
0.39	GO:0007399	nervous system development
0.38	GO:1990194	cytoplasmic U snRNP body assembly
0.38	GO:0035154	terminal cell fate specification, open tracheal system
0.38	GO:0120035	regulation of plasma membrane bounded cell projection organization
0.38	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.38	GO:0045175	basal protein localization

0.59	GO:0003723	RNA binding
0.37	GO:0051393	alpha-actinin binding
0.35	GO:0042802	identical protein binding

0.61	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.38	GO:0034718	SMN-Gemin2 complex
0.37	GO:0031974	membrane-enclosed lumen
0.37	GO:0032797	SMN complex
0.37	GO:0031594	neuromuscular junction
0.36	GO:0098794	postsynapse
0.35	GO:0044446	intracellular organelle part
0.35	GO:0099512	supramolecular fiber
0.34	GO:0030529	intracellular ribonucleoprotein complex

tr|T1EMU1|T1EMU1_HELRO
Uncharacterized protein
Search

tr|T1EMU2|T1EMU2_HELRO
Uncharacterized protein
Search

0.77

GO:0035725

sodium ion transmembrane transport

0.81

GO:0005272

sodium channel activity

0.30

GO:0031224

intrinsic component of membrane

tr|T1EMU3|T1EMU3_HELRO
Uncharacterized protein
Search

tr|T1EMU4|T1EMU4_HELRO
Uncharacterized protein
Search

tr|T1EMU5|T1EMU5_HELRO
Uncharacterized protein
Search

tr|T1EMU6|T1EMU6_HELRO
Uncharacterized protein
Search

0.51	GO:0006278	RNA-dependent DNA biosynthetic process
0.46	GO:0036065	fucosylation
0.44	GO:0043413	macromolecule glycosylation
0.44	GO:0009101	glycoprotein biosynthetic process
0.39	GO:0005975	carbohydrate metabolic process
0.39	GO:0036211	protein modification process
0.38	GO:0044267	cellular protein metabolic process

0.51	GO:0003964	RNA-directed DNA polymerase activity
0.49	GO:0046872	metal ion binding
0.47	GO:0008107	galactoside 2-alpha-L-fucosyltransferase activity
0.38	GO:0003676	nucleic acid binding

0.46

GO:0032580

Golgi cisterna membrane

0.51

EC:2.7.7.49

GO:0003964

tr|T1EMU7|T1EMU7_HELRO
Uncharacterized protein
Search

tr|T1EMU8|T1EMU8_HELRO
Uncharacterized protein
Search

tr|T1EMU9|T1EMU9_HELRO
Uncharacterized protein
Search

tr|T1EMV0|T1EMV0_HELRO
Uncharacterized protein
Search

tr|T1EMV1|T1EMV1_HELRO
Uncharacterized protein
Search

tr|T1EMV2|T1EMV2_HELRO
Uncharacterized protein
Search

tr|T1EMV3|T1EMV3_HELRO
Uncharacterized protein
Search

tr|T1EMV4|T1EMV4_HELRO
Uncharacterized protein
Search

0.52

GO:0035556

intracellular signal transduction

0.50

GO:0046872

metal ion binding

0.40	GO:0005622	intracellular
0.30	GO:0044425	membrane part

tr|T1EMV5|T1EMV5_HELRO
Uncharacterized protein
Search

tr|T1EMV6|T1EMV6_HELRO
Uncharacterized protein
Search

tr|T1EMV7|T1EMV7_HELRO
Uncharacterized protein
Search

tr|T1EMV8|T1EMV8_HELRO
Uncharacterized protein
Search

tr|T1EMV9|T1EMV9_HELRO
Uncharacterized protein
Search

tr|T1EMW0|T1EMW0_HELRO
Uncharacterized protein
Search

tr|T1EMW1|T1EMW1_HELRO
Uncharacterized protein
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tr|T1EMW2|T1EMW2_HELRO
Uncharacterized protein
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tr|T1EMW3|T1EMW3_HELRO
Uncharacterized protein
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tr|T1EMW4|T1EMW4_HELRO
Uncharacterized protein
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tr|T1EMW5|T1EMW5_HELRO
Uncharacterized protein
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tr|T1EMW6|T1EMW6_HELRO
Uncharacterized protein
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tr|T1EMW7|T1EMW7_HELRO
Uncharacterized protein
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tr|T1EMW8|T1EMW8_HELRO
Uncharacterized protein
Search

0.38

GO:0035556

intracellular signal transduction

0.53

GO:0046872

metal ion binding

0.34

GO:0005622

intracellular

tr|T1EMW9|T1EMW9_HELRO
Uncharacterized protein
Search

0.62	GO:0000226	microtubule cytoskeleton organization
0.38	GO:0016973	poly(A)+ mRNA export from nucleus
0.38	GO:0009166	nucleotide catabolic process
0.37	GO:0007018	microtubule-based movement
0.37	GO:0005978	glycogen biosynthetic process
0.34	GO:0055085	transmembrane transport

0.51	GO:0008270	zinc ion binding
0.44	GO:0003676	nucleic acid binding
0.37	GO:0102752	1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis)
0.37	GO:0003844	1,4-alpha-glucan branching enzyme activity
0.37	GO:0003777	microtubule motor activity
0.37	GO:0008017	microtubule binding
0.36	GO:0003924	GTPase activity
0.36	GO:0032550	purine ribonucleoside binding
0.36	GO:0019001	guanyl nucleotide binding
0.35	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.59	GO:0015630	microtubule cytoskeleton
0.37	GO:0005643	nuclear pore
0.37	GO:0099513	polymeric cytoskeletal fiber
0.30	GO:0016020	membrane

0.37

EC:2.4.1.18

GO:0003844

tr|T1EMX0|T1EMX0_HELRO
Uncharacterized protein
Search

tr|T1EMX1|T1EMX1_HELRO
Uncharacterized protein
Search

tr|T1EMX2|T1EMX2_HELRO
Uncharacterized protein
Search

tr|T1EMX3|T1EMX3_HELRO
Uncharacterized protein
Search

0.36

GO:0090305

nucleic acid phosphodiester bond hydrolysis

0.51	GO:0003676	nucleic acid binding
0.36	GO:0004519	endonuclease activity
0.35	GO:0046872	metal ion binding

0.30

GO:0031224

intrinsic component of membrane

tr|T1EMX4|T1EMX4_HELRO
Uncharacterized protein
Search

0.85	GO:0016201	synaptic target inhibition
0.80	GO:0008045	motor neuron axon guidance

0.30

GO:0044425

membrane part

tr|T1EMX5|T1EMX5_HELRO
Uncharacterized protein
Search

tr|T1EMX6|T1EMX6_HELRO
Uncharacterized protein
Search

tr|T1EMX7|T1EMX7_HELRO
Uncharacterized protein
Search

tr|T1EMX8|T1EMX8_HELRO
Uncharacterized protein
Search

tr|T1EMX9|T1EMX9_HELRO
Uncharacterized protein
Search

0.51	GO:0003676	nucleic acid binding
0.36	GO:0046872	metal ion binding

0.30

GO:0044425

membrane part

tr|T1EMY0|T1EMY0_HELRO
Uncharacterized protein
Search

tr|T1EMY1|T1EMY1_HELRO
Uncharacterized protein
Search

0.46	GO:0007059	chromosome segregation
0.44	GO:0051301	cell division
0.39	GO:0019538	protein metabolic process
0.39	GO:0016071	mRNA metabolic process
0.39	GO:0016310	phosphorylation
0.38	GO:0043412	macromolecule modification
0.38	GO:0044260	cellular macromolecule metabolic process
0.38	GO:0010467	gene expression
0.38	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic
0.38	GO:0065007	biological regulation

0.48	GO:0008017	microtubule binding
0.41	GO:0000829	inositol heptakisphosphate kinase activity
0.40	GO:0003676	nucleic acid binding
0.40	GO:0008270	zinc ion binding
0.39	GO:0016787	hydrolase activity
0.39	GO:0017076	purine nucleotide binding
0.39	GO:0097367	carbohydrate derivative binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0140096	catalytic activity, acting on a protein
0.38	GO:0008144	drug binding

0.50	GO:0005876	spindle microtubule
0.50	GO:0000940	condensed chromosome outer kinetochore
0.40	GO:0005634	nucleus
0.38	GO:0000932	P-body
0.38	GO:0016281	eukaryotic translation initiation factor 4F complex
0.37	GO:0032300	mismatch repair complex
0.37	GO:1902494	catalytic complex
0.37	GO:0010494	cytoplasmic stress granule
0.36	GO:0070013	intracellular organelle lumen
0.35	GO:0032432	actin filament bundle

0.39

GO:0016787

tr|T1EMY2|T1EMY2_HELRO
Uncharacterized protein
Search

tr|T1EMY3|T1EMY3_HELRO
Uncharacterized protein
Search

tr|T1EMY4|T1EMY4_HELRO
Uncharacterized protein
Search

tr|T1EMY5|T1EMY5_HELRO
Uncharacterized protein
Search

tr|T1EMY6|T1EMY6_HELRO
Uncharacterized protein
Search

tr|T1EMY7|T1EMY7_HELRO
Uncharacterized protein
Search

tr|T1EMY8|T1EMY8_HELRO
Uncharacterized protein
Search

tr|T1EMY9|T1EMY9_HELRO
Uncharacterized protein
Search

tr|T1EMZ0|T1EMZ0_HELRO
Uncharacterized protein
Search

0.11	Repressor of the inhibitor of the protein kinase

0.36	GO:0016310	phosphorylation
0.35	GO:0006357	regulation of transcription by RNA polymerase II
0.34	GO:0007275	multicellular organism development

0.68	GO:0046983	protein dimerization activity
0.36	GO:0016301	kinase activity
0.35	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.33	GO:0003677	DNA binding

0.34	GO:0005654	nucleoplasm
0.32	GO:0005737	cytoplasm

tr|T1EMZ1|T1EMZ1_HELRO
Uncharacterized protein
Search

tr|T1EMZ2|T1EMZ2_HELRO
Uncharacterized protein
Search

tr|T1EMZ3|T1EMZ3_HELRO
Uncharacterized protein
Search

tr|T1EMZ4|T1EMZ4_HELRO
Uncharacterized protein
Search

tr|T1EMZ5|T1EMZ5_HELRO
Uncharacterized protein
Search

tr|T1EMZ6|T1EMZ6_HELRO
Uncharacterized protein
Search

tr|T1EMZ7|T1EMZ7_HELRO
Uncharacterized protein
Search

tr|T1EMZ8|T1EMZ8_HELRO
Uncharacterized protein
Search

tr|T1EMZ9|T1EMZ9_HELRO
Uncharacterized protein
Search

tr|T1EN00|T1EN00_HELRO
Uncharacterized protein
Search

tr|T1EN01|T1EN01_HELRO
Uncharacterized protein
Search

tr|T1EN02|T1EN02_HELRO
Uncharacterized protein
Search

tr|T1EN03|T1EN03_HELRO
Uncharacterized protein
Search

tr|T1EN04|T1EN04_HELRO
Uncharacterized protein
Search

tr|T1EN05|T1EN05_HELRO
Uncharacterized protein
Search

tr|T1EN06|T1EN06_HELRO
Uncharacterized protein
Search

tr|T1EN07|T1EN07_HELRO
Uncharacterized protein
Search

tr|T1EN08|T1EN08_HELRO
Uncharacterized protein
Search

tr|T1EN09|T1EN09_HELRO
Uncharacterized protein
Search

tr|T1EN10|T1EN10_HELRO
Uncharacterized protein
Search

tr|T1EN11|T1EN11_HELRO
Uncharacterized protein
Search

tr|T1EN12|T1EN12_HELRO
Uncharacterized protein
Search

tr|T1EN13|T1EN13_HELRO
Uncharacterized protein
Search

tr|T1EN14|T1EN14_HELRO
Uncharacterized protein
Search

tr|T1EN15|T1EN15_HELRO
Uncharacterized protein
Search

tr|T1EN16|T1EN16_HELRO
Uncharacterized protein
Search

tr|T1EN17|T1EN17_HELRO
Uncharacterized protein
Search

tr|T1EN18|T1EN18_HELRO
Uncharacterized protein
Search

tr|T1EN19|T1EN19_HELRO
Uncharacterized protein
Search

tr|T1EN20|T1EN20_HELRO
Uncharacterized protein
Search

tr|T1EN21|T1EN21_HELRO
Uncharacterized protein
Search

tr|T1EN22|T1EN22_HELRO
Uncharacterized protein
Search

tr|T1EN23|T1EN23_HELRO
Uncharacterized protein
Search

0.73	GO:0008658	penicillin binding
0.51	GO:0016740	transferase activity

0.30

GO:0044425

membrane part

0.51

GO:0016740

tr|T1EN24|T1EN24_HELRO
Uncharacterized protein
Search

tr|T1EN25|T1EN25_HELRO
Uncharacterized protein
Search

tr|T1EN26|T1EN26_HELRO
Uncharacterized protein
Search

tr|T1EN27|T1EN27_HELRO
Uncharacterized protein
Search

tr|T1EN28|T1EN28_HELRO
Uncharacterized protein
Search

tr|T1EN29|T1EN29_HELRO
Uncharacterized protein
Search

tr|T1EN30|T1EN30_HELRO
Uncharacterized protein
Search

tr|T1EN31|T1EN31_HELRO
Uncharacterized protein
Search

tr|T1EN32|T1EN32_HELRO
Uncharacterized protein
Search

tr|T1EN33|T1EN33_HELRO
Uncharacterized protein
Search

0.35

GO:0006334

nucleosome assembly

0.33

GO:0003677

DNA binding

0.35	GO:0000786	nucleosome
0.33	GO:0005634	nucleus
0.30	GO:0044425	membrane part

tr|T1EN34|T1EN34_HELRO
Uncharacterized protein
Search

0.35	GO:0006334	nucleosome assembly
0.35	GO:0006182	cGMP biosynthetic process
0.33	GO:0035556	intracellular signal transduction

0.35	GO:0004383	guanylate cyclase activity
0.33	GO:0003677	DNA binding
0.32	GO:1901265	nucleoside phosphate binding
0.32	GO:0036094	small molecule binding

0.35	GO:0000786	nucleosome
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:4.6.1.2

GO:0004383

tr|T1EN35|T1EN35_HELRO
Uncharacterized protein
Search

tr|T1EN36|T1EN36_HELRO
Uncharacterized protein
Search

0.57	Haloacid dehalogenase hydrolase domain-containing protein 1a

0.37	GO:0016311	dephosphorylation
0.36	GO:0005975	carbohydrate metabolic process
0.33	GO:0046173	polyol biosynthetic process
0.32	GO:0009117	nucleotide metabolic process
0.32	GO:0016310	phosphorylation
0.32	GO:0044249	cellular biosynthetic process

0.50	GO:0016787	hydrolase activity
0.40	GO:0008801	beta-phosphoglucomutase activity
0.36	GO:0000287	magnesium ion binding
0.33	GO:0019205	nucleobase-containing compound kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.50	EC:3	GO:0016787
0.40	KEGG:R02728	GO:0008801

tr|T1EN37|T1EN37_HELRO
Uncharacterized protein
Search

tr|T1EN38|T1EN38_HELRO
Uncharacterized protein
Search

tr|T1EN39|T1EN39_HELRO
Uncharacterized protein
Search

tr|T1EN40|T1EN40_HELRO
Uncharacterized protein
Search

tr|T1EN41|T1EN41_HELRO
Uncharacterized protein
Search

0.46	GO:0007165	signal transduction
0.41	GO:0034220	ion transmembrane transport
0.39	GO:0006468	protein phosphorylation

0.46	GO:0005230	extracellular ligand-gated ion channel activity
0.44	GO:0099600	transmembrane receptor activity
0.42	GO:0038023	signaling receptor activity
0.41	GO:0046872	metal ion binding
0.39	GO:0004672	protein kinase activity
0.37	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0044425

membrane part

tr|T1EN42|T1EN42_HELRO
Uncharacterized protein
Search

tr|T1EN43|T1EN43_HELRO
Uncharacterized protein
Search

tr|T1EN44|T1EN44_HELRO
Uncharacterized protein
Search

tr|T1EN45|T1EN45_HELRO
Uncharacterized protein
Search

tr|T1EN46|T1EN46_HELRO
Uncharacterized protein
Search

0.71	GO:0035871	protein K11-linked deubiquitination
0.58	GO:0070536	protein K63-linked deubiquitination
0.58	GO:0071108	protein K48-linked deubiquitination
0.56	GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process
0.54	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling
0.50	GO:0006955	immune response
0.48	GO:0032717	negative regulation of interleukin-8 production
0.47	GO:0051028	mRNA transport
0.47	GO:1900181	negative regulation of protein localization to nucleus
0.45	GO:0000122	negative regulation of transcription by RNA polymerase II

0.59	GO:0008270	zinc ion binding
0.56	GO:0070530	K63-linked polyubiquitin modification-dependent protein binding
0.55	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.52	GO:0003677	DNA binding
0.47	GO:1990380	Lys48-specific deubiquitinase activity

0.48	GO:0005634	nucleus
0.40	GO:0005737	cytoplasm

tr|T1EN47|T1EN47_HELRO
Uncharacterized protein
Search

0.58	GO:0016567	protein ubiquitination
0.47	GO:0018108	peptidyl-tyrosine phosphorylation
0.41	GO:0043044	ATP-dependent chromatin remodeling
0.40	GO:0016569	covalent chromatin modification
0.38	GO:0006351	transcription, DNA-templated
0.38	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.38	GO:1903506	regulation of nucleic acid-templated transcription
0.38	GO:0010468	regulation of gene expression
0.37	GO:0006508	proteolysis
0.37	GO:0006629	lipid metabolic process

0.58	GO:0004842	ubiquitin-protein transferase activity
0.47	GO:0004713	protein tyrosine kinase activity
0.44	GO:0016874	ligase activity
0.41	GO:0031491	nucleosome binding
0.40	GO:0043168	anion binding
0.40	GO:0030554	adenyl nucleotide binding
0.40	GO:0043565	sequence-specific DNA binding
0.40	GO:0032555	purine ribonucleotide binding
0.40	GO:0008144	drug binding
0.39	GO:0003700	DNA binding transcription factor activity

0.42	GO:0016589	NURF complex
0.30	GO:0016020	membrane

0.47	EC:2.7.10	GO:0004713
0.58	KEGG:R03876	GO:0004842

tr|T1EN48|T1EN48_HELRO
Uncharacterized protein
Search

tr|T1EN49|T1EN49_HELRO
Uncharacterized protein
Search

tr|T1EN50|T1EN50_HELRO
Uncharacterized protein
Search

0.47	GO:0048082	regulation of adult chitin-containing cuticle pigmentation
0.46	GO:0040003	chitin-based cuticle development
0.45	GO:0030100	regulation of endocytosis
0.38	GO:0070447	positive regulation of oligodendrocyte progenitor proliferation
0.37	GO:0140058	neuron projection arborization
0.37	GO:1904447	folic acid import across plasma membrane
0.37	GO:0003223	ventricular compact myocardium morphogenesis
0.37	GO:0060982	coronary artery morphogenesis
0.37	GO:0061156	pulmonary artery morphogenesis
0.37	GO:0003139	secondary heart field specification

0.68	GO:0005509	calcium ion binding
0.35	GO:0016964	alpha-2 macroglobulin receptor activity
0.35	GO:0032050	clathrin heavy chain binding
0.35	GO:0034185	apolipoprotein binding
0.34	GO:0032403	protein complex binding

0.45	GO:0016324	apical plasma membrane
0.37	GO:0043235	receptor complex
0.37	GO:0031526	brush border membrane
0.36	GO:0005768	endosome
0.36	GO:0009897	external side of plasma membrane
0.36	GO:0030139	endocytic vesicle
0.36	GO:0005905	clathrin-coated pit
0.36	GO:0030425	dendrite
0.36	GO:0030424	axon
0.35	GO:0005829	cytosol

tr|T1EN51|T1EN51_HELRO
Uncharacterized protein
Search

tr|T1EN52|T1EN52_HELRO
Uncharacterized protein
Search

tr|T1EN53|T1EN53_HELRO
Uncharacterized protein
Search

tr|T1EN54|T1EN54_HELRO
Uncharacterized protein
Search

0.54

GO:0035556

intracellular signal transduction

0.53

GO:0046872

metal ion binding

0.41	GO:0005622	intracellular
0.30	GO:0044425	membrane part

tr|T1EN55|T1EN55_HELRO
Uncharacterized protein
Search

tr|T1EN56|T1EN56_HELRO
Uncharacterized protein
Search

tr|T1EN57|T1EN57_HELRO
Uncharacterized protein
Search

tr|T1EN58|T1EN58_HELRO
Uncharacterized protein
Search

tr|T1EN59|T1EN59_HELRO
Kinase
Search

0.32

Kinase

0.82	GO:0032958	inositol phosphate biosynthetic process
0.57	GO:0016310	phosphorylation
0.34	GO:0120009	intermembrane lipid transfer

0.59	GO:0016301	kinase activity
0.34	GO:0120013	intermembrane lipid transfer activity

0.43	GO:0005730	nucleolus
0.42	GO:0005654	nucleoplasm
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|T1EN60|T1EN60_HELRO
Uncharacterized protein
Search

tr|T1EN61|T1EN61_HELRO
Uncharacterized protein
Search

tr|T1EN62|T1EN62_HELRO
Uncharacterized protein
Search

tr|T1EN63|T1EN63_HELRO
Uncharacterized protein
Search

tr|T1EN64|T1EN64_HELRO
Uncharacterized protein
Search

tr|T1EN65|T1EN65_HELRO
Uncharacterized protein
Search

tr|T1EN66|T1EN66_HELRO
Uncharacterized protein
Search

tr|T1EN67|T1EN67_HELRO
Uncharacterized protein
Search

tr|T1EN68|T1EN68_HELRO
Uncharacterized protein
Search

tr|T1EN69|T1EN69_HELRO
Uncharacterized protein
Search

tr|T1EN70|T1EN70_HELRO
Uncharacterized protein
Search

tr|T1EN71|T1EN71_HELRO
Uncharacterized protein
Search

tr|T1EN72|T1EN72_HELRO
Uncharacterized protein
Search

tr|T1EN73|T1EN73_HELRO
Uncharacterized protein
Search

tr|T1EN74|T1EN74_HELRO
Uncharacterized protein
Search

tr|T1EN75|T1EN75_HELRO
Uncharacterized protein
Search

tr|T1EN76|T1EN76_HELRO
Uncharacterized protein
Search

0.54	GO:0016567	protein ubiquitination
0.39	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.39	GO:0080090	regulation of primary metabolic process
0.39	GO:0010468	regulation of gene expression
0.39	GO:0051171	regulation of nitrogen compound metabolic process
0.38	GO:0010558	negative regulation of macromolecule biosynthetic process
0.38	GO:0031327	negative regulation of cellular biosynthetic process
0.37	GO:0044265	cellular macromolecule catabolic process
0.37	GO:0007412	axon target recognition
0.37	GO:0035076	ecdysone receptor-mediated signaling pathway

0.54	GO:0004842	ubiquitin-protein transferase activity
0.45	GO:0003676	nucleic acid binding
0.40	GO:0000829	inositol heptakisphosphate kinase activity
0.38	GO:0061659	ubiquitin-like protein ligase activity
0.38	GO:0004535	poly(A)-specific ribonuclease activity
0.38	GO:0008270	zinc ion binding
0.37	GO:0003700	DNA binding transcription factor activity
0.37	GO:0030371	translation repressor activity
0.37	GO:0016874	ligase activity
0.36	GO:0005515	protein binding

0.38	GO:0005634	nucleus
0.38	GO:0030015	CCR4-NOT core complex
0.37	GO:0000932	P-body
0.35	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.38	EC:3.1.13.4	GO:0004535
0.54	KEGG:R03876	GO:0004842

tr|T1EN77|T1EN77_HELRO
Uncharacterized protein
Search

tr|T1EN78|T1EN78_HELRO
Uncharacterized protein
Search

0.30

GO:0044425

membrane part

tr|T1EN79|T1EN79_HELRO
Uncharacterized protein
Search

tr|T1EN80|T1EN80_HELRO
Uncharacterized protein
Search

tr|T1EN82|T1EN82_HELRO
Uncharacterized protein
Search

tr|T1EN83|T1EN83_HELRO
Uncharacterized protein
Search

0.49

GO:0006468

protein phosphorylation

0.50	GO:0004672	protein kinase activity
0.50	GO:0046872	metal ion binding
0.45	GO:0030554	adenyl nucleotide binding
0.44	GO:0097367	carbohydrate derivative binding
0.44	GO:0008144	drug binding
0.44	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0003676	nucleic acid binding

tr|T1EN84|T1EN84_HELRO
Uncharacterized protein
Search

tr|T1EN85|T1EN85_HELRO
Uncharacterized protein
Search

0.69	pancreatic lipase-related protein 2-like

0.60	GO:0006629	lipid metabolic process
0.42	GO:1901575	organic substance catabolic process
0.36	GO:0006968	cellular defense response
0.35	GO:0007586	digestion
0.35	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.35	GO:0006396	RNA processing
0.33	GO:0032504	multicellular organism reproduction
0.33	GO:0060079	excitatory postsynaptic potential
0.33	GO:0035235	ionotropic glutamate receptor signaling pathway
0.32	GO:0006811	ion transport

0.70	GO:0052689	carboxylic ester hydrolase activity
0.57	GO:0016298	lipase activity
0.38	GO:0008201	heparin binding
0.36	GO:0008408	3'-5' exonuclease activity
0.33	GO:1901265	nucleoside phosphate binding
0.33	GO:0036094	small molecule binding
0.33	GO:0003676	nucleic acid binding
0.33	GO:0005234	extracellularly glutamate-gated ion channel activity
0.33	GO:0004970	ionotropic glutamate receptor activity

0.66	GO:0005576	extracellular region
0.38	GO:0000176	nuclear exosome (RNase complex)
0.34	GO:0005886	plasma membrane
0.33	GO:0098794	postsynapse
0.30	GO:0016021	integral component of membrane

0.70	EC:3.1.1 EC:3.1.1.1	GO:0052689
0.70	KEGG:R00630	GO:0052689

tr|T1EN86|T1EN86_HELRO
Uncharacterized protein
Search

tr|T1EN87|T1EN87_HELRO
Uncharacterized protein
Search

tr|T1EN88|T1EN88_HELRO
Uncharacterized protein
Search

0.47	Selenophosphate synthetase

0.77	GO:0016260	selenocysteine biosynthetic process
0.57	GO:0016310	phosphorylation
0.35	GO:0046041	ITP metabolic process
0.35	GO:0006172	ADP biosynthetic process
0.34	GO:0046039	GTP metabolic process
0.34	GO:0046033	AMP metabolic process
0.34	GO:0018342	protein prenylation

0.80	GO:0004756	selenide, water dikinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0042802	identical protein binding
0.35	GO:0046899	nucleoside triphosphate adenylate kinase activity
0.34	GO:0004017	adenylate kinase activity
0.34	GO:0008318	protein prenyltransferase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding

0.34	GO:0005759	mitochondrial matrix
0.30	GO:0016020	membrane

0.80	EC:2.7.9.3	GO:0004756
0.80	KEGG:R03595	GO:0004756

tr|T1EN89|T1EN89_HELRO
Uncharacterized protein
Search

tr|T1EN90|T1EN90_HELRO
Uncharacterized protein
Search

tr|T1EN91|T1EN91_HELRO
Uncharacterized protein
Search

0.40	tctex1 domain-containing protein 1-like

tr|T1EN92|T1EN92_HELRO
Uncharacterized protein
Search

DOCK7

0.63	Dedicator of cytokinesis protein 6

0.77	GO:0007264	small GTPase mediated signal transduction
0.66	GO:0065009	regulation of molecular function
0.34	GO:0045200	establishment of neuroblast polarity
0.34	GO:1904754	positive regulation of vascular associated smooth muscle cell migration
0.33	GO:0033138	positive regulation of peptidyl-serine phosphorylation
0.33	GO:0007409	axonogenesis
0.33	GO:0000226	microtubule cytoskeleton organization
0.32	GO:0022027	interkinetic nuclear migration
0.32	GO:0002244	hematopoietic progenitor cell differentiation
0.32	GO:0043473	pigmentation

0.75	GO:0005085	guanyl-nucleotide exchange factor activity
0.33	GO:0048365	Rac GTPase binding

0.45	GO:0005622	intracellular
0.32	GO:0005925	focal adhesion
0.32	GO:0043234	protein complex
0.32	GO:0044422	organelle part
0.32	GO:0043227	membrane-bounded organelle

tr|T1EN93|T1EN93_HELRO
Uncharacterized protein
Search

tr|T1EN94|T1EN94_HELRO
Uncharacterized protein
Search

0.60	GO:0006278	RNA-dependent DNA biosynthetic process
0.55	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.41	GO:0055114	oxidation-reduction process

0.60	GO:0003964	RNA-directed DNA polymerase activity
0.56	GO:0004519	endonuclease activity
0.51	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.45	GO:0004527	exonuclease activity
0.42	GO:0046872	metal ion binding

0.39	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm

0.60

EC:2.7.7.49

GO:0003964

tr|T1EN95|T1EN95_HELRO
Uncharacterized protein
Search

tr|T1EN96|T1EN96_HELRO
Uncharacterized protein
Search

tr|T1EN97|T1EN97_HELRO
Uncharacterized protein
Search

tr|T1EN98|T1EN98_HELRO
Uncharacterized protein
Search

tr|T1EN99|T1EN99_HELRO
Galactoside 2-alpha-L-fucosyltransferase
Search

0.40	Galactoside 2-alpha-L-fucosyltransferase

0.80	GO:0036065	fucosylation
0.72	GO:0006486	protein glycosylation
0.60	GO:0005975	carbohydrate metabolic process

0.84

GO:0008107

galactoside 2-alpha-L-fucosyltransferase activity

0.79	GO:0032580	Golgi cisterna membrane
0.30	GO:0016021	integral component of membrane

0.84

EC:2.4.1.69

GO:0008107

tr|T1ENA0|T1ENA0_HELRO
Uncharacterized protein
Search

tr|T1ENA1|T1ENA1_HELRO
Uncharacterized protein
Search

tr|T1ENA2|T1ENA2_HELRO
Uncharacterized protein
Search

tr|T1ENA3|T1ENA3_HELRO
Uncharacterized protein
Search

tr|T1ENA4|T1ENA4_HELRO
Uncharacterized protein
Search

0.72

GO:0071805

potassium ion transmembrane transport

0.85	GO:0060072	large conductance calcium-activated potassium channel activity
0.74	GO:0005249	voltage-gated potassium channel activity
0.33	GO:0005509	calcium ion binding

0.74

GO:0008076

voltage-gated potassium channel complex

tr|T1ENA5|T1ENA5_HELRO
Uncharacterized protein
Search

0.73	GO:0071805	potassium ion transmembrane transport
0.48	GO:0043050	pharyngeal pumping
0.46	GO:0048149	behavioral response to ethanol
0.46	GO:0046928	regulation of neurotransmitter secretion
0.45	GO:0045214	sarcomere organization
0.40	GO:0040011	locomotion
0.34	GO:0006888	ER to Golgi vesicle-mediated transport
0.34	GO:0034765	regulation of ion transmembrane transport
0.33	GO:0045892	negative regulation of transcription, DNA-templated
0.33	GO:0006886	intracellular protein transport

0.85	GO:0060072	large conductance calcium-activated potassium channel activity
0.76	GO:0005249	voltage-gated potassium channel activity
0.38	GO:0005515	protein binding
0.33	GO:0046872	metal ion binding

0.76	GO:0008076	voltage-gated potassium channel complex
0.47	GO:0055120	striated muscle dense body
0.46	GO:0031430	M band
0.43	GO:0045202	synapse
0.34	GO:0030127	COPII vesicle coat
0.33	GO:0030054	cell junction
0.33	GO:0005634	nucleus

tr|T1ENA6|T1ENA6_HELRO
Uncharacterized protein
Search

0.73	GO:0071804	cellular potassium ion transport
0.62	GO:0098662	inorganic cation transmembrane transport
0.35	GO:1900074	negative regulation of neuromuscular synaptic transmission
0.35	GO:0045433	male courtship behavior, veined wing generated song production
0.35	GO:0008582	regulation of synaptic growth at neuromuscular junction
0.35	GO:0048512	circadian behavior
0.34	GO:0034765	regulation of ion transmembrane transport
0.33	GO:0042493	response to drug

0.85	GO:0060072	large conductance calcium-activated potassium channel activity
0.75	GO:0005249	voltage-gated potassium channel activity
0.33	GO:0005515	protein binding
0.32	GO:0046872	metal ion binding

0.75	GO:0008076	voltage-gated potassium channel complex
0.34	GO:0043025	neuronal cell body
0.34	GO:0043005	neuron projection

tr|T1ENA7|T1ENA7_HELRO
Uncharacterized protein
Search

0.57	Calcium-activated potassium channel slowpoke

0.73	GO:0071805	potassium ion transmembrane transport
0.44	GO:0043050	pharyngeal pumping
0.43	GO:0048149	behavioral response to ethanol
0.42	GO:0046928	regulation of neurotransmitter secretion
0.42	GO:0045214	sarcomere organization
0.38	GO:0040011	locomotion

0.85	GO:0060072	large conductance calcium-activated potassium channel activity
0.70	GO:0005249	voltage-gated potassium channel activity
0.37	GO:0005515	protein binding
0.32	GO:0046872	metal ion binding

0.70	GO:0008076	voltage-gated potassium channel complex
0.43	GO:0055120	striated muscle dense body
0.42	GO:0031430	M band
0.40	GO:0045202	synapse

tr|T1ENA8|T1ENA8_HELRO
Uncharacterized protein
Search

tr|T1ENA9|T1ENA9_HELRO
Uncharacterized protein
Search

tr|T1ENB0|T1ENB0_HELRO
Uncharacterized protein
Search

0.40

GO:0006468

protein phosphorylation

0.41	GO:0004672	protein kinase activity
0.38	GO:0030554	adenyl nucleotide binding
0.38	GO:0097367	carbohydrate derivative binding
0.38	GO:0008144	drug binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0031224

intrinsic component of membrane

tr|T1ENB1|T1ENB1_HELRO
Uncharacterized protein
Search

0.49

GO:0003676

nucleic acid binding

0.30

GO:0044425

membrane part

tr|T1ENB2|T1ENB2_HELRO
Uncharacterized protein
Search

tr|T1ENB3|T1ENB3_HELRO
Uncharacterized protein
Search

tr|T1ENB4|T1ENB4_HELRO
Uncharacterized protein
Search

0.34	GO:0015074	DNA integration
0.34	GO:0035556	intracellular signal transduction
0.33	GO:0006313	transposition, DNA-mediated
0.33	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic

0.50	GO:0003676	nucleic acid binding
0.35	GO:0046872	metal ion binding
0.34	GO:0004803	transposase activity
0.33	GO:0004523	RNA-DNA hybrid ribonuclease activity

0.32	GO:0005622	intracellular
0.30	GO:0044425	membrane part

0.33

EC:3.1.26.4

GO:0004523

tr|T1ENB5|T1ENB5_HELRO
Uncharacterized protein
Search

tr|T1ENB6|T1ENB6_HELRO
Uncharacterized protein
Search

tr|T1ENB7|T1ENB7_HELRO
Uncharacterized protein
Search

tr|T1ENB8|T1ENB8_HELRO
Uncharacterized protein
Search

0.30

GO:0044425

membrane part

tr|T1ENB9|T1ENB9_HELRO
Uncharacterized protein
Search

tr|T1ENC0|T1ENC0_HELRO
Uncharacterized protein
Search

tr|T1ENC1|T1ENC1_HELRO
Uncharacterized protein
Search

tr|T1ENC2|T1ENC2_HELRO
Uncharacterized protein
Search

tr|T1ENC3|T1ENC3_HELRO
Uncharacterized protein
Search

tr|T1ENC4|T1ENC4_HELRO
Uncharacterized protein
Search

tr|T1ENC5|T1ENC5_HELRO
Uncharacterized protein
Search

tr|T1ENC6|T1ENC6_HELRO
Uncharacterized protein
Search

tr|T1ENC7|T1ENC7_HELRO
Uncharacterized protein
Search

tr|T1ENC8|T1ENC8_HELRO
Uncharacterized protein
Search

tr|T1ENC9|T1ENC9_HELRO
Uncharacterized protein
Search

tr|T1END0|T1END0_HELRO
Uncharacterized protein
Search

tr|T1END1|T1END1_HELRO
Uncharacterized protein
Search

0.48

GO:0035556

intracellular signal transduction

0.49	GO:0046872	metal ion binding
0.37	GO:0003677	DNA binding

0.38	GO:0005622	intracellular
0.30	GO:0044425	membrane part

tr|T1END2|T1END2_HELRO
Uncharacterized protein
Search

tr|T1END3|T1END3_HELRO
Uncharacterized protein
Search

0.43	GO:0006032	chitin catabolic process
0.42	GO:0016998	cell wall macromolecule catabolic process
0.41	GO:0001682	tRNA 5'-leader removal
0.39	GO:1903506	regulation of nucleic acid-templated transcription
0.39	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.39	GO:0010468	regulation of gene expression
0.39	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.36	GO:0006351	transcription, DNA-templated

0.55	GO:0032550	purine ribonucleoside binding
0.55	GO:0019001	guanyl nucleotide binding
0.47	GO:0032555	purine ribonucleotide binding
0.47	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0004568	chitinase activity
0.41	GO:0008270	zinc ion binding
0.41	GO:0004526	ribonuclease P activity
0.41	GO:0003700	DNA binding transcription factor activity
0.39	GO:0003676	nucleic acid binding

0.43	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.43

EC:3.2.1.14

GO:0004568

tr|T1END4|T1END4_HELRO
Uncharacterized protein
Search

0.11	Pogo transposable element with KRAB (Fragment)

0.54

GO:0003677

DNA binding

tr|T1END5|T1END5_HELRO
Uncharacterized protein
Search

tr|T1END6|T1END6_HELRO
Uncharacterized protein
Search

TNFAIP8

0.93	Tumor necrosis factor alpha-induced protein 8

0.74	GO:0042981	regulation of apoptotic process
0.51	GO:2000117	negative regulation of cysteine-type endopeptidase activity
0.48	GO:0043069	negative regulation of programmed cell death
0.48	GO:0006915	apoptotic process
0.47	GO:0043068	positive regulation of programmed cell death
0.44	GO:0007435	salivary gland morphogenesis
0.44	GO:0046330	positive regulation of JNK cascade
0.43	GO:0070507	regulation of microtubule cytoskeleton organization
0.41	GO:0010506	regulation of autophagy
0.36	GO:0032611	interleukin-1 beta production

0.52	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.33	GO:0005515	protein binding

0.44	GO:0005654	nucleoplasm
0.40	GO:0042995	cell projection
0.39	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|T1END7|T1END7_HELRO
Uncharacterized protein
Search

tr|T1END8|T1END8_HELRO
Uncharacterized protein
Search

tr|T1END9|T1END9_HELRO
Uncharacterized protein
Search

tr|T1ENE0|T1ENE0_HELRO
Uncharacterized protein
Search

tr|T1ENE1|T1ENE1_HELRO
Uncharacterized protein
Search

tr|T1ENE2|T1ENE2_HELRO
Uncharacterized protein
Search

tr|T1ENE3|T1ENE3_HELRO
Uncharacterized protein
Search

tr|T1ENE4|T1ENE4_HELRO
Uncharacterized protein
Search

tr|T1ENE5|T1ENE5_HELRO
Uncharacterized protein
Search

tr|T1ENE6|T1ENE6_HELRO
Uncharacterized protein
Search

tr|T1ENE7|T1ENE7_HELRO
Uncharacterized protein
Search

tr|T1ENE8|T1ENE8_HELRO
Uncharacterized protein
Search

tr|T1ENE9|T1ENE9_HELRO
Uncharacterized protein
Search

tr|T1ENF0|T1ENF0_HELRO
Uncharacterized protein
Search

tr|T1ENF1|T1ENF1_HELRO
Uncharacterized protein
Search

0.54

GO:0046872

metal ion binding

tr|T1ENF2|T1ENF2_HELRO
Uncharacterized protein
Search

0.60	GO:1904668	positive regulation of ubiquitin protein ligase activity
0.58	GO:0006298	mismatch repair

0.60	GO:0097027	ubiquitin-protein transferase activator activity
0.60	GO:0010997	anaphase-promoting complex binding
0.59	GO:0030983	mismatched DNA binding
0.46	GO:0032559	adenyl ribonucleotide binding
0.45	GO:0008144	drug binding
0.45	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0016020

membrane

tr|T1ENF3|T1ENF3_HELRO
Uncharacterized protein
Search

tr|T1ENF4|T1ENF4_HELRO
Uncharacterized protein
Search

0.69

GO:0006364

rRNA processing

tr|T1ENF5|T1ENF5_HELRO
Uncharacterized protein
Search

0.55	GO:0007186	G-protein coupled receptor signaling pathway
0.55	GO:0007018	microtubule-based movement

0.60	GO:0008528	G-protein coupled peptide receptor activity
0.55	GO:0003777	microtubule motor activity
0.55	GO:0008017	microtubule binding
0.44	GO:0030554	adenyl nucleotide binding
0.43	GO:0097367	carbohydrate derivative binding
0.43	GO:0008144	drug binding
0.43	GO:0035639	purine ribonucleoside triphosphate binding

0.54	GO:0005874	microtubule
0.30	GO:0044425	membrane part

tr|T1ENF6|T1ENF6_HELRO
Uncharacterized protein
Search

tr|T1ENF7|T1ENF7_HELRO
Uncharacterized protein
Search

0.77	GO:0007229	integrin-mediated signaling pathway
0.70	GO:0007155	cell adhesion
0.49	GO:0043588	skin development
0.48	GO:0072001	renal system development
0.48	GO:0016477	cell migration
0.47	GO:0097062	dendritic spine maintenance
0.47	GO:0035295	tube development
0.46	GO:0009888	tissue development
0.46	GO:0035024	negative regulation of Rho protein signal transduction
0.46	GO:0035640	exploration behavior

0.45	GO:0005178	integrin binding
0.45	GO:0002020	protease binding
0.45	GO:0038132	neuregulin binding
0.44	GO:0031994	insulin-like growth factor I binding
0.43	GO:0046982	protein heterodimerization activity
0.42	GO:0045296	cadherin binding
0.41	GO:0043236	laminin binding
0.39	GO:0001968	fibronectin binding
0.38	GO:0005518	collagen binding
0.37	GO:0019904	protein domain specific binding

0.79	GO:0008305	integrin complex
0.49	GO:0016323	basolateral plasma membrane
0.49	GO:0009897	external side of plasma membrane
0.47	GO:0071438	invadopodium membrane
0.47	GO:0031527	filopodium membrane
0.46	GO:0060076	excitatory synapse
0.44	GO:0030056	hemidesmosome
0.44	GO:0097060	synaptic membrane
0.43	GO:0045178	basal part of cell
0.42	GO:0005604	basement membrane

0.34

EC:2.8.2

GO:0008146

tr|T1ENF8|T1ENF8_HELRO
Uncharacterized protein
Search

tr|T1ENF9|T1ENF9_HELRO
Uncharacterized protein
Search

tr|T1ENG0|T1ENG0_HELRO
Uncharacterized protein
Search

tr|T1ENG1|T1ENG1_HELRO
Peptidylprolyl isomerase
Search

0.21	Peptidylprolyl isomerase

0.71

GO:0000413

protein peptidyl-prolyl isomerization

0.71

GO:0003755

peptidyl-prolyl cis-trans isomerase activity

0.30

GO:0031224

intrinsic component of membrane

0.71

EC:5.2.1.8

GO:0003755

tr|T1ENG2|T1ENG2_HELRO
Uncharacterized protein
Search

tr|T1ENG3|T1ENG3_HELRO
Uncharacterized protein
Search

tr|T1ENG4|T1ENG4_HELRO
Uncharacterized protein
Search

tr|T1ENG5|T1ENG5_HELRO
Uncharacterized protein
Search

tr|T1ENG6|T1ENG6_HELRO
Uncharacterized protein
Search

tr|T1ENG7|T1ENG7_HELRO
Uncharacterized protein
Search

tr|T1ENG8|T1ENG8_HELRO
Uncharacterized protein
Search

tr|T1ENG9|T1ENG9_HELRO
Uncharacterized protein
Search

0.87	GO:1900074	negative regulation of neuromuscular synaptic transmission
0.87	GO:0042694	muscle cell fate specification
0.87	GO:0007522	visceral muscle development
0.87	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity
0.86	GO:0051124	synaptic growth at neuromuscular junction
0.86	GO:0042051	compound eye photoreceptor development
0.85	GO:0007435	salivary gland morphogenesis
0.81	GO:0007411	axon guidance
0.80	GO:0043410	positive regulation of MAPK cascade
0.61	GO:0007509	mesoderm migration involved in gastrulation

0.87

GO:0030297

transmembrane receptor protein tyrosine kinase activator activity

0.87	GO:0061177	type Is terminal bouton
0.87	GO:0061176	type Ib terminal bouton
0.82	GO:0008021	synaptic vesicle
0.73	GO:0005615	extracellular space

tr|T1ENH0|T1ENH0_HELRO
Uncharacterized protein
Search

tr|T1ENH1|T1ENH1_HELRO
Uncharacterized protein
Search

tr|T1ENH2|T1ENH2_HELRO
Uncharacterized protein
Search

0.43	GO:0008062	eclosion rhythm
0.42	GO:0007479	leg disc proximal/distal pattern formation
0.42	GO:0007469	antennal development
0.41	GO:0045475	locomotor rhythm
0.39	GO:0007420	brain development
0.39	GO:0045944	positive regulation of transcription by RNA polymerase II
0.35	GO:0045494	photoreceptor cell maintenance
0.35	GO:0043586	tongue development
0.35	GO:0003416	endochondral bone growth
0.34	GO:0060021	palate development

0.51	GO:0003676	nucleic acid binding
0.33	GO:0005515	protein binding
0.32	GO:0046872	metal ion binding

0.37	GO:0005634	nucleus
0.33	GO:0043233	organelle lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

tr|T1ENH3|T1ENH3_HELRO
Uncharacterized protein
Search

tr|T1ENH4|T1ENH4_HELRO
Uncharacterized protein
Search

tr|T1ENH5|T1ENH5_HELRO
Uncharacterized protein
Search

tr|T1ENH6|T1ENH6_HELRO
Uncharacterized protein
Search

0.80	GO:0051660	establishment of centrosome localization
0.80	GO:0048696	regulation of collateral sprouting in absence of injury
0.79	GO:0060242	contact inhibition
0.78	GO:0021535	cell migration in hindbrain
0.78	GO:0035845	photoreceptor cell outer segment organization
0.78	GO:0022010	central nervous system myelination
0.76	GO:0022011	myelination in peripheral nervous system
0.76	GO:0048048	embryonic eye morphogenesis
0.75	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity
0.75	GO:0007405	neuroblast proliferation

0.71	GO:0016324	apical plasma membrane
0.51	GO:0005923	bicellular tight junction
0.45	GO:0005737	cytoplasm

tr|T1ENH7|T1ENH7_HELRO
Uncharacterized protein
Search

0.42	GO:0050794	regulation of cellular process
0.41	GO:0023051	regulation of signaling
0.41	GO:0048583	regulation of response to stimulus
0.41	GO:0010556	regulation of macromolecule biosynthetic process
0.41	GO:0051171	regulation of nitrogen compound metabolic process
0.41	GO:0080090	regulation of primary metabolic process
0.41	GO:0010468	regulation of gene expression
0.41	GO:0009891	positive regulation of biosynthetic process
0.40	GO:0065009	regulation of molecular function
0.40	GO:0010604	positive regulation of macromolecule metabolic process

0.44	GO:0005515	protein binding
0.42	GO:0017111	nucleoside-triphosphatase activity
0.41	GO:0098772	molecular function regulator
0.41	GO:0017076	purine nucleotide binding
0.41	GO:0097367	carbohydrate derivative binding
0.41	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0008270	zinc ion binding
0.40	GO:0003676	nucleic acid binding
0.40	GO:0008144	drug binding
0.39	GO:0050825	ice binding

0.45	GO:0005634	nucleus
0.39	GO:0005667	transcription factor complex
0.39	GO:0043233	organelle lumen
0.38	GO:1902494	catalytic complex
0.38	GO:0044446	intracellular organelle part
0.37	GO:0000932	P-body
0.37	GO:0010494	cytoplasmic stress granule
0.36	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0005783	endoplasmic reticulum
0.36	GO:0019028	viral capsid

0.42

EC:3.6.1.15

GO:0017111

tr|T1ENH8|T1ENH8_HELRO
Uncharacterized protein
Search

0.74

GO:0006869

lipid transport

0.77

GO:0005319

lipid transporter activity

tr|T1ENH9|T1ENH9_HELRO
Uncharacterized protein
Search

tr|T1ENI0|T1ENI0_HELRO
Uncharacterized protein
Search

tr|T1ENI1|T1ENI1_HELRO
Uncharacterized protein
Search

tr|T1ENI2|T1ENI2_HELRO
Uncharacterized protein
Search

tr|T1ENI3|T1ENI3_HELRO
Uncharacterized protein
Search

tr|T1ENI4|T1ENI4_HELRO
Uncharacterized protein
Search

tr|T1ENI5|T1ENI5_HELRO
Uncharacterized protein
Search

tr|T1ENI6|T1ENI6_HELRO
Uncharacterized protein
Search

0.45	GO:0007015	actin filament organization
0.42	GO:0035023	regulation of Rho protein signal transduction
0.42	GO:0006936	muscle contraction
0.41	GO:0006897	endocytosis
0.40	GO:0032467	positive regulation of cytokinesis
0.40	GO:0065009	regulation of molecular function
0.38	GO:0043412	macromolecule modification
0.38	GO:0006413	translational initiation
0.38	GO:0035556	intracellular signal transduction
0.38	GO:0002229	defense response to oomycetes

0.43	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.42	GO:0017022	myosin binding
0.41	GO:0003779	actin binding
0.41	GO:0005516	calmodulin binding
0.41	GO:0005509	calcium ion binding
0.40	GO:0017076	purine nucleotide binding
0.40	GO:0097367	carbohydrate derivative binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0003924	GTPase activity
0.40	GO:0003723	RNA binding

0.40	GO:0044430	cytoskeletal part
0.39	GO:0099512	supramolecular fiber
0.37	GO:0015629	actin cytoskeleton
0.37	GO:0015630	microtubule cytoskeleton
0.37	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm
0.35	GO:0043234	protein complex
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.38

EC:1.2.99.7

GO:0033727

tr|T1ENI7|T1ENI7_HELRO
Uncharacterized protein
Search

tr|T1ENI8|T1ENI8_HELRO
Uncharacterized protein
Search

tr|T1ENI9|T1ENI9_HELRO
Uncharacterized protein
Search

tr|T1ENJ0|T1ENJ0_HELRO
Uncharacterized protein
Search

0.76	GO:0007601	visual perception
0.48	GO:0007166	cell surface receptor signaling pathway

0.46

GO:0005887

integral component of plasma membrane

tr|T1ENJ1|T1ENJ1_HELRO
Uncharacterized protein
Search

tr|T1ENJ2|T1ENJ2_HELRO
Uncharacterized protein
Search

tr|T1ENJ3|T1ENJ3_HELRO
Uncharacterized protein
Search

tr|T1ENJ4|T1ENJ4_HELRO
Uncharacterized protein
Search

0.49	GO:1902683	regulation of receptor localization to synapse
0.49	GO:1904861	excitatory synapse assembly
0.46	GO:0050804	modulation of chemical synaptic transmission
0.36	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway
0.36	GO:0010976	positive regulation of neuron projection development
0.36	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.35	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.35	GO:0001934	positive regulation of protein phosphorylation
0.35	GO:0008542	visual learning
0.35	GO:0070372	regulation of ERK1 and ERK2 cascade

0.37	GO:0005105	type 1 fibroblast growth factor receptor binding
0.35	GO:0050839	cell adhesion molecule binding
0.35	GO:0044325	ion channel binding
0.33	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.33	GO:0004526	ribonuclease P activity
0.33	GO:0030246	carbohydrate binding
0.32	GO:0003723	RNA binding
0.32	GO:0022857	transmembrane transporter activity

0.46	GO:0030425	dendrite
0.36	GO:0042734	presynaptic membrane
0.35	GO:0060077	inhibitory synapse
0.35	GO:0014069	postsynaptic density
0.34	GO:0009986	cell surface
0.33	GO:0000172	ribonuclease MRP complex
0.33	GO:0030677	ribonuclease P complex
0.33	GO:0045211	postsynaptic membrane
0.32	GO:0019866	organelle inner membrane
0.32	GO:0031966	mitochondrial membrane

0.33

EC:3.1.26.5

GO:0004526

tr|T1ENJ5|T1ENJ5_HELRO
Uncharacterized protein
Search

tr|T1ENJ6|T1ENJ6_HELRO
Uncharacterized protein
Search

tr|T1ENJ7|T1ENJ7_HELRO
Uncharacterized protein
Search

tr|T1ENJ8|T1ENJ8_HELRO
Uncharacterized protein
Search

0.42	GO:0055114	oxidation-reduction process
0.41	GO:0036211	protein modification process
0.40	GO:0044267	cellular protein metabolic process
0.40	GO:0007018	microtubule-based movement
0.39	GO:0043632	modification-dependent macromolecule catabolic process
0.39	GO:0030163	protein catabolic process
0.38	GO:0000012	single strand break repair
0.38	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.38	GO:0007275	multicellular organism development
0.38	GO:0006399	tRNA metabolic process

0.44	GO:0046872	metal ion binding
0.43	GO:0016491	oxidoreductase activity
0.42	GO:0003676	nucleic acid binding
0.41	GO:0004842	ubiquitin-protein transferase activity
0.40	GO:0004549	tRNA-specific ribonuclease activity
0.40	GO:0003777	microtubule motor activity
0.40	GO:0008017	microtubule binding
0.39	GO:0032559	adenyl ribonucleotide binding
0.39	GO:0008144	drug binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding

0.42	GO:0005634	nucleus
0.38	GO:0044446	intracellular organelle part
0.37	GO:1902555	endoribonuclease complex
0.37	GO:0031461	cullin-RING ubiquitin ligase complex
0.37	GO:0005578	proteinaceous extracellular matrix
0.36	GO:0031974	membrane-enclosed lumen
0.36	GO:0005829	cytosol
0.35	GO:0012505	endomembrane system
0.34	GO:0031975	envelope
0.34	GO:0043234	protein complex

0.43	EC:1	GO:0016491
0.41	KEGG:R03876	GO:0004842

tr|T1ENJ9|T1ENJ9_HELRO
Uncharacterized protein
Search

0.45	GO:0060255	regulation of macromolecule metabolic process
0.44	GO:0051171	regulation of nitrogen compound metabolic process
0.44	GO:0080090	regulation of primary metabolic process
0.44	GO:0031323	regulation of cellular metabolic process
0.43	GO:0009889	regulation of biosynthetic process
0.42	GO:0043412	macromolecule modification
0.41	GO:0016310	phosphorylation
0.40	GO:0019538	protein metabolic process
0.40	GO:0016070	RNA metabolic process
0.40	GO:0044260	cellular macromolecule metabolic process

0.44	GO:0003700	DNA binding transcription factor activity
0.43	GO:0016772	transferase activity, transferring phosphorus-containing groups
0.40	GO:0140096	catalytic activity, acting on a protein
0.40	GO:0005515	protein binding
0.39	GO:0008270	zinc ion binding
0.39	GO:0098772	molecular function regulator
0.39	GO:0030554	adenyl nucleotide binding
0.38	GO:0008144	drug binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0032555	purine ribonucleotide binding

0.41	GO:0005634	nucleus
0.39	GO:0031461	cullin-RING ubiquitin ligase complex
0.37	GO:0044446	intracellular organelle part
0.37	GO:0015630	microtubule cytoskeleton
0.36	GO:0030134	COPII-coated ER to Golgi transport vesicle
0.36	GO:0020011	apicoplast
0.36	GO:0030133	transport vesicle
0.36	GO:0012506	vesicle membrane
0.36	GO:0030117	membrane coat
0.35	GO:0098805	whole membrane

0.43

EC:2.7

GO:0016772

tr|T1ENK0|T1ENK0_HELRO
Uncharacterized protein
Search

0.59	GO:1903432	regulation of TORC1 signaling
0.47	GO:0006470	protein dephosphorylation

0.47	GO:0004721	phosphoprotein phosphatase activity
0.44	GO:0004386	helicase activity
0.39	GO:0030554	adenyl nucleotide binding
0.39	GO:0097367	carbohydrate derivative binding
0.39	GO:0008144	drug binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0003676	nucleic acid binding

0.30

GO:0031224

intrinsic component of membrane

0.47

GO:0004721

tr|T1ENK1|T1ENK1_HELRO
Uncharacterized protein
Search

tr|T1ENK2|T1ENK2_HELRO
Uncharacterized protein
Search

0.52	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.33	GO:0006413	translational initiation

0.59

GO:0003723

RNA binding

0.50	GO:0005730	nucleolus
0.50	GO:0030684	preribosome
0.40	GO:0019013	viral nucleocapsid
0.34	GO:0005852	eukaryotic translation initiation factor 3 complex

tr|T1ENK3|T1ENK3_HELRO
Uncharacterized protein
Search

tr|T1ENK4|T1ENK4_HELRO
Uncharacterized protein
Search

tr|T1ENK5|T1ENK5_HELRO
Uncharacterized protein
Search

tr|T1ENK6|T1ENK6_HELRO
Uncharacterized protein
Search

tr|T1ENK7|T1ENK7_HELRO
Uncharacterized protein
Search

0.52

GO:0007165

signal transduction

0.40

GO:0046872

metal ion binding

0.30

GO:0044425

membrane part

tr|T1ENK8|T1ENK8_HELRO
Uncharacterized protein
Search

tr|T1ENK9|T1ENK9_HELRO
Eukaryotic translation initiation factor 3 subunit K
Search

EIF3K

0.72	Eukaryotic translation initiation factor 3 subunit K

0.78	GO:0006446	regulation of translational initiation
0.75	GO:0001731	formation of translation preinitiation complex

0.74	GO:0043022	ribosome binding
0.73	GO:0003743	translation initiation factor activity
0.33	GO:0005515	protein binding
0.33	GO:0005509	calcium ion binding

0.78	GO:0005852	eukaryotic translation initiation factor 3 complex
0.74	GO:0016282	eukaryotic 43S preinitiation complex
0.74	GO:0033290	eukaryotic 48S preinitiation complex
0.53	GO:0005634	nucleus
0.43	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

tr|T1ENL0|T1ENL0_HELRO
Uncharacterized protein
Search

tr|T1ENL1|T1ENL1_HELRO
Uncharacterized protein
Search

0.57	GO:0090501	RNA phosphodiester bond hydrolysis
0.53	GO:0006396	RNA processing
0.43	GO:0006508	proteolysis
0.40	GO:0048015	phosphatidylinositol-mediated signaling
0.39	GO:0006401	RNA catabolic process
0.39	GO:0046854	phosphatidylinositol phosphorylation
0.38	GO:0042254	ribosome biogenesis
0.38	GO:0071897	DNA biosynthetic process
0.38	GO:0016072	rRNA metabolic process
0.37	GO:0051304	chromosome separation

0.57	GO:0004540	ribonuclease activity
0.52	GO:0003723	RNA binding
0.51	GO:0004181	metallocarboxypeptidase activity
0.45	GO:0008270	zinc ion binding
0.38	GO:0003887	DNA-directed DNA polymerase activity
0.38	GO:0004430	1-phosphatidylinositol 4-kinase activity
0.37	GO:0005245	voltage-gated calcium channel activity
0.36	GO:0008810	cellulase activity
0.36	GO:0004519	endonuclease activity
0.35	GO:0000287	magnesium ion binding

0.38	GO:0000178	exosome (RNase complex)
0.37	GO:0005891	voltage-gated calcium channel complex
0.37	GO:0009898	cytoplasmic side of plasma membrane
0.37	GO:0034457	Mpp10 complex
0.37	GO:1905369	endopeptidase complex
0.36	GO:0005732	small nucleolar ribonucleoprotein complex
0.35	GO:0005737	cytoplasm

0.51	EC:3.4.17	GO:0004181
0.38	KEGG:R03361	GO:0004430

tr|T1ENL2|T1ENL2_HELRO
Uncharacterized protein
Search

0.72	GO:0007155	cell adhesion
0.68	GO:0050900	leukocyte migration
0.62	GO:0010572	positive regulation of platelet activation
0.61	GO:0033623	regulation of integrin activation
0.60	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.59	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling
0.58	GO:0002687	positive regulation of leukocyte migration
0.56	GO:0006954	inflammatory response

0.70	GO:0030246	carbohydrate binding
0.62	GO:0033691	sialic acid binding
0.59	GO:0048306	calcium-dependent protein binding
0.57	GO:0008201	heparin binding
0.57	GO:0001530	lipopolysaccharide binding
0.50	GO:0005509	calcium ion binding

0.62	GO:0031092	platelet alpha granule membrane
0.56	GO:0009897	external side of plasma membrane
0.52	GO:0005615	extracellular space
0.49	GO:0005887	integral component of plasma membrane

tr|T1ENL3|T1ENL3_HELRO
Uncharacterized protein
Search

tr|T1ENL4|T1ENL4_HELRO
Uncharacterized protein
Search

tr|T1ENL5|T1ENL5_HELRO
Uncharacterized protein
Search

tr|T1ENL6|T1ENL6_HELRO
Uncharacterized protein
Search

0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.56	GO:0007631	feeding behavior
0.42	GO:0001994	norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure
0.41	GO:0045907	positive regulation of vasoconstriction
0.41	GO:0045987	positive regulation of smooth muscle contraction
0.40	GO:0019933	cAMP-mediated signaling
0.40	GO:0022410	circadian sleep/wake cycle process
0.40	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.39	GO:0030186	melatonin metabolic process
0.39	GO:0007267	cell-cell signaling

0.71	GO:0004930	G-protein coupled receptor activity
0.63	GO:0001653	peptide receptor activity
0.35	GO:0050254	rhodopsin kinase activity
0.35	GO:0016500	protein-hormone receptor activity
0.34	GO:0042277	peptide binding
0.33	GO:0005515	protein binding
0.33	GO:0005198	structural molecule activity

0.41	GO:0005886	plasma membrane
0.34	GO:0030127	COPII vesicle coat
0.33	GO:0000139	Golgi membrane
0.33	GO:0005829	cytosol
0.32	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.35

EC:2.7.11.14

GO:0050254

tr|T1ENL7|T1ENL7_HELRO
Uncharacterized protein
Search

tr|T1ENL8|T1ENL8_HELRO
Uncharacterized protein
Search

0.30

GO:0044425

membrane part

tr|T1ENL9|T1ENL9_HELRO
Uncharacterized protein
Search

tr|T1ENM0|T1ENM0_HELRO
Uncharacterized protein
Search

0.46	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.46	GO:1903506	regulation of nucleic acid-templated transcription
0.46	GO:0010468	regulation of gene expression

0.64	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.55	GO:0030246	carbohydrate binding

0.49	GO:0005634	nucleus
0.30	GO:0044425	membrane part

tr|T1ENM1|T1ENM1_HELRO
Uncharacterized protein
Search

tr|T1ENM2|T1ENM2_HELRO
Uncharacterized protein
Search

tr|T1ENM3|T1ENM3_HELRO
Uncharacterized protein
Search

tr|T1ENM4|T1ENM4_HELRO
Uncharacterized protein
Search

tr|T1ENM5|T1ENM5_HELRO
Uncharacterized protein
Search

tr|T1ENM6|T1ENM6_HELRO
Uncharacterized protein
Search

0.70	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.54	GO:0006278	RNA-dependent DNA biosynthetic process
0.34	GO:0006281	DNA repair
0.34	GO:0006464	cellular protein modification process
0.33	GO:0006796	phosphate-containing compound metabolic process

0.73	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.54	GO:0003964	RNA-directed DNA polymerase activity
0.51	GO:0003676	nucleic acid binding
0.33	GO:0046983	protein dimerization activity
0.33	GO:0004725	protein tyrosine phosphatase activity
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0016020

membrane

0.73

EC:3.1.26.4

GO:0004523

tr|T1ENM7|T1ENM7_HELRO
Uncharacterized protein
Search

tr|T1ENM8|T1ENM8_HELRO
Uncharacterized protein
Search

tr|T1ENM9|T1ENM9_HELRO
Uncharacterized protein
Search

tr|T1ENN0|T1ENN0_HELRO
Uncharacterized protein
Search

0.73	GO:0007596	blood coagulation
0.52	GO:0001775	cell activation
0.51	GO:0051258	protein polymerization
0.44	GO:0007165	signal transduction
0.43	GO:0006508	proteolysis
0.42	GO:0042176	regulation of protein catabolic process
0.40	GO:0050790	regulation of catalytic activity
0.39	GO:0007155	cell adhesion

0.52	GO:0030674	protein binding, bridging
0.49	GO:0005102	receptor binding
0.43	GO:0008233	peptidase activity
0.40	GO:0030234	enzyme regulator activity
0.38	GO:0030246	carbohydrate binding

0.56	GO:0005577	fibrinogen complex
0.41	GO:1905369	endopeptidase complex
0.34	GO:0044424	intracellular part
0.30	GO:0031224	intrinsic component of membrane

0.43

GO:0008233

tr|T1ENN1|T1ENN1_HELRO
Uncharacterized protein
Search

0.70	GO:0007596	blood coagulation
0.52	GO:0006898	receptor-mediated endocytosis
0.49	GO:0051103	DNA ligation involved in DNA repair
0.45	GO:0016310	phosphorylation
0.44	GO:0071897	DNA biosynthetic process
0.44	GO:0006260	DNA replication
0.43	GO:0006310	DNA recombination
0.42	GO:0006508	proteolysis

0.57	GO:0005044	scavenger receptor activity
0.48	GO:0003910	DNA ligase (ATP) activity
0.46	GO:0016301	kinase activity
0.45	GO:0004252	serine-type endopeptidase activity
0.43	GO:0008270	zinc ion binding
0.39	GO:0032559	adenyl ribonucleotide binding
0.39	GO:0003677	DNA binding
0.39	GO:0008144	drug binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding

0.47	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.48

EC:6.5.1.1

GO:0003910

tr|T1ENN2|T1ENN2_HELRO
Uncharacterized protein
Search

0.45	GO:0007059	chromosome segregation
0.44	GO:0051301	cell division
0.43	GO:0099120	socially cooperative development
0.42	GO:0036211	protein modification process
0.40	GO:0044267	cellular protein metabolic process
0.40	GO:0016310	phosphorylation
0.39	GO:0065007	biological regulation
0.39	GO:0051716	cellular response to stimulus
0.39	GO:0007154	cell communication
0.38	GO:0023052	signaling

0.47	GO:0008017	microtubule binding
0.42	GO:0140096	catalytic activity, acting on a protein
0.41	GO:0017076	purine nucleotide binding
0.41	GO:0097367	carbohydrate derivative binding
0.41	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0017111	nucleoside-triphosphatase activity
0.40	GO:0016301	kinase activity
0.40	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.39	GO:0008144	drug binding
0.39	GO:0003676	nucleic acid binding

0.49	GO:0005876	spindle microtubule
0.48	GO:0000940	condensed chromosome outer kinetochore
0.39	GO:0005634	nucleus
0.37	GO:0032300	mismatch repair complex
0.36	GO:1990234	transferase complex
0.36	GO:0070013	intracellular organelle lumen
0.36	GO:0015629	actin cytoskeleton
0.35	GO:0017053	transcriptional repressor complex
0.35	GO:0030666	endocytic vesicle membrane
0.35	GO:0000932	P-body

0.41

EC:3.6.1.15

GO:0017111

tr|T1ENN3|T1ENN3_HELRO
Uncharacterized protein
Search

tr|T1ENN4|T1ENN4_HELRO
Uncharacterized protein
Search

0.82

GO:0007596

blood coagulation

tr|T1ENN5|T1ENN5_HELRO
Uncharacterized protein
Search

0.69	GO:0007596	blood coagulation
0.44	GO:0001775	cell activation
0.43	GO:0051258	protein polymerization
0.40	GO:0007165	signal transduction
0.39	GO:0045087	innate immune response
0.39	GO:0042176	regulation of protein catabolic process
0.37	GO:0006508	proteolysis
0.37	GO:0050790	regulation of catalytic activity

0.44	GO:0030674	protein binding, bridging
0.42	GO:0005102	receptor binding
0.38	GO:0030246	carbohydrate binding
0.38	GO:0008233	peptidase activity
0.37	GO:0030234	enzyme regulator activity
0.35	GO:0046872	metal ion binding
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.46	GO:0005577	fibrinogen complex
0.38	GO:1905369	endopeptidase complex
0.33	GO:0044424	intracellular part
0.30	GO:0016020	membrane

0.38

GO:0008233

tr|T1ENN6|T1ENN6_HELRO
Uncharacterized protein
Search

tr|T1ENN7|T1ENN7_HELRO
Uncharacterized protein
Search

tr|T1ENN8|T1ENN8_HELRO
Uncharacterized protein
Search

tr|T1ENN9|T1ENN9_HELRO
Uncharacterized protein
Search

tr|T1ENP0|T1ENP0_HELRO
Uncharacterized protein
Search

tr|T1ENP1|T1ENP1_HELRO
Uncharacterized protein
Search

0.41	GO:0016573	histone acetylation
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:0010468	regulation of gene expression
0.35	GO:0043043	peptide biosynthetic process
0.34	GO:0010467	gene expression
0.34	GO:0009059	macromolecule biosynthetic process

0.41	GO:0004402	histone acetyltransferase activity
0.41	GO:0003713	transcription coactivator activity
0.38	GO:0008270	zinc ion binding
0.36	GO:0003735	structural constituent of ribosome

0.39	GO:0020011	apicoplast
0.37	GO:0005634	nucleus
0.35	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.41

GO:0004402

tr|T1ENP2|T1ENP2_HELRO
Uncharacterized protein
Search

tr|T1ENP3|T1ENP3_HELRO
Uncharacterized protein
Search

SH3BGRL2

0.82	SH3 domain binding glutamate rich protein like 2

0.38	GO:0045454	cell redox homeostasis
0.37	GO:0022900	electron transport chain

0.52	GO:0017124	SH3 domain binding
0.39	GO:0015035	protein disulfide oxidoreductase activity
0.37	GO:0009055	electron transfer activity

0.75	GO:0031965	nuclear membrane
0.66	GO:0005654	nucleoplasm
0.45	GO:0070062	extracellular exosome
0.41	GO:0005737	cytoplasm

tr|T1ENP4|T1ENP4_HELRO
Uncharacterized protein
Search

tr|T1ENP5|T1ENP5_HELRO
Uncharacterized protein
Search

tr|T1ENP6|T1ENP6_HELRO
Uncharacterized protein
Search

tr|T1ENP7|T1ENP7_HELRO
Uncharacterized protein
Search

tr|T1ENP8|T1ENP8_HELRO
Uncharacterized protein
Search

tr|T1ENP9|T1ENP9_HELRO
Uncharacterized protein
Search

0.46	GO:0016180	snRNA processing
0.46	GO:0006413	translational initiation
0.42	GO:0032259	methylation
0.39	GO:0050794	regulation of cellular process
0.38	GO:0051171	regulation of nitrogen compound metabolic process
0.38	GO:0060255	regulation of macromolecule metabolic process
0.38	GO:0080090	regulation of primary metabolic process
0.38	GO:0043412	macromolecule modification
0.38	GO:0009889	regulation of biosynthetic process
0.37	GO:0016310	phosphorylation

0.47	GO:0030246	carbohydrate binding
0.46	GO:0003743	translation initiation factor activity
0.42	GO:0008168	methyltransferase activity
0.39	GO:0003700	DNA binding transcription factor activity
0.38	GO:0016301	kinase activity
0.37	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.37	GO:0140096	catalytic activity, acting on a protein
0.37	GO:0046872	metal ion binding
0.36	GO:0030554	adenyl nucleotide binding
0.36	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding

0.46	GO:0032039	integrator complex
0.36	GO:0022627	cytosolic small ribosomal subunit
0.35	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex
0.35	GO:0017053	transcriptional repressor complex
0.30	GO:0016020	membrane

0.42	EC:2.1.1	GO:0008168
0.34	KEGG:R03532	GO:0004601

tr|T1ENQ0|T1ENQ0_HELRO
Uncharacterized protein
Search

tr|T1ENQ1|T1ENQ1_HELRO
Uncharacterized protein
Search

tr|T1ENQ2|T1ENQ2_HELRO
Putative rRNA methyltransferase
Search

0.63	AdoMet-dependent rRNA methyltransferase

0.75	GO:0000453	enzyme-directed rRNA 2'-O-methylation
0.45	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.45	GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.35	GO:0051301	cell division
0.34	GO:0006437	tyrosyl-tRNA aminoacylation
0.32	GO:0055114	oxidation-reduction process

0.70	GO:0008649	rRNA methyltransferase activity
0.44	GO:0008171	O-methyltransferase activity
0.36	GO:0003924	GTPase activity
0.36	GO:0032550	purine ribonucleoside binding
0.36	GO:0019001	guanyl nucleotide binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0004831	tyrosine-tRNA ligase activity
0.33	GO:0000049	tRNA binding
0.33	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

0.70	GO:0005730	nucleolus
0.55	GO:0030684	preribosome
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.70	EC:2.1.1	GO:0008649
0.34	KEGG:R02918	GO:0004831

tr|T1ENQ3|T1ENQ3_HELRO
Uncharacterized protein
Search

tr|T1ENQ4|T1ENQ4_HELRO
Uncharacterized protein
Search

tr|T1ENQ5|T1ENQ5_HELRO
Uncharacterized protein
Search

tr|T1ENQ6|T1ENQ6_HELRO
Uncharacterized protein
Search

tr|T1ENQ7|T1ENQ7_HELRO
Uncharacterized protein
Search

tr|T1ENQ8|T1ENQ8_HELRO
Nitric oxide synthase-interacting protein homolog
Search

0.86	Nitric oxide synthase-interacting protein homolog

0.71	GO:0016567	protein ubiquitination
0.40	GO:0051001	negative regulation of nitric-oxide synthase activity
0.35	GO:0007275	multicellular organism development
0.33	GO:0000398	mRNA splicing, via spliceosome
0.33	GO:0006351	transcription, DNA-templated
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression
0.32	GO:0055114	oxidation-reduction process

0.75	GO:0061630	ubiquitin protein ligase activity
0.33	GO:0046983	protein dimerization activity
0.33	GO:0004517	nitric-oxide synthase activity
0.33	GO:0003700	DNA binding transcription factor activity
0.32	GO:0003723	RNA binding

0.59	GO:0005634	nucleus
0.39	GO:0005737	cytoplasm
0.34	GO:0005667	transcription factor complex
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0019013	viral nucleocapsid
0.32	GO:1902494	catalytic complex
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.33

EC:1.14.13.39

GO:0004517

tr|T1ENQ9|T1ENQ9_HELRO
Uncharacterized protein
Search

0.45	GO:0098655	cation transmembrane transport
0.42	GO:0065007	biological regulation
0.41	GO:0036211	protein modification process
0.40	GO:0050896	response to stimulus
0.40	GO:0006796	phosphate-containing compound metabolic process
0.39	GO:0044267	cellular protein metabolic process
0.39	GO:0046486	glycerolipid metabolic process
0.38	GO:0007154	cell communication
0.37	GO:0099120	socially cooperative development
0.37	GO:0023052	signaling

0.45	GO:0008324	cation transmembrane transporter activity
0.41	GO:0003713	transcription coactivator activity
0.40	GO:0016772	transferase activity, transferring phosphorus-containing groups
0.39	GO:0140096	catalytic activity, acting on a protein
0.39	GO:0030554	adenyl nucleotide binding
0.39	GO:0097367	carbohydrate derivative binding
0.39	GO:0043168	anion binding
0.38	GO:0042578	phosphoric ester hydrolase activity
0.38	GO:0003676	nucleic acid binding
0.38	GO:0008144	drug binding

0.43	GO:0005634	nucleus
0.38	GO:0044448	cell cortex part
0.37	GO:0032991	macromolecular complex
0.37	GO:0071782	endoplasmic reticulum tubular network
0.36	GO:0038201	TOR complex
0.36	GO:0005741	mitochondrial outer membrane
0.36	GO:0005657	replication fork
0.36	GO:0005886	plasma membrane
0.35	GO:0070013	intracellular organelle lumen
0.35	GO:0005794	Golgi apparatus

0.40

EC:2.7

GO:0016772

tr|T1ENR0|T1ENR0_HELRO
Uncharacterized protein
Search

tr|T1ENR1|T1ENR1_HELRO
Uncharacterized protein
Search

tr|T1ENR2|T1ENR2_HELRO
Uncharacterized protein
Search

tr|T1ENR3|T1ENR3_HELRO
Uncharacterized protein
Search

tr|T1ENR4|T1ENR4_HELRO
Uncharacterized protein
Search

tr|T1ENR5|T1ENR5_HELRO
Uncharacterized protein
Search

0.47	GO:0006325	chromatin organization
0.47	GO:0006355	regulation of transcription, DNA-templated
0.46	GO:0018205	peptidyl-lysine modification
0.45	GO:0016579	protein deubiquitination
0.45	GO:0006475	internal protein amino acid acetylation
0.40	GO:0006511	ubiquitin-dependent protein catabolic process
0.40	GO:0008213	protein alkylation
0.38	GO:0043414	macromolecule methylation
0.38	GO:0071824	protein-DNA complex subunit organization
0.37	GO:0048015	phosphatidylinositol-mediated signaling

0.49	GO:0003700	DNA binding transcription factor activity
0.48	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.45	GO:0004402	histone acetyltransferase activity
0.41	GO:0018024	histone-lysine N-methyltransferase activity
0.38	GO:0004430	1-phosphatidylinositol 4-kinase activity
0.37	GO:0008270	zinc ion binding
0.37	GO:0004127	cytidylate kinase activity
0.37	GO:0004017	adenylate kinase activity
0.36	GO:0004842	ubiquitin-protein transferase activity
0.36	GO:0003777	microtubule motor activity

0.41	GO:0005634	nucleus
0.38	GO:1905369	endopeptidase complex
0.37	GO:0005694	chromosome
0.36	GO:0043234	protein complex
0.36	GO:0034708	methyltransferase complex
0.35	GO:0005618	cell wall
0.35	GO:0015630	microtubule cytoskeleton
0.35	GO:0044430	cytoskeletal part
0.35	GO:0005576	extracellular region
0.35	GO:0043233	organelle lumen

0.48	EC:3.4.19.12	GO:0036459
0.38	KEGG:R03361	GO:0004430

tr|T1ENR6|T1ENR6_HELRO
Uncharacterized protein
Search

0.72	GO:0007155	cell adhesion
0.48	GO:0060243	negative regulation of cell growth involved in contact inhibition
0.47	GO:0090675	intermicrovillar adhesion
0.47	GO:0032532	regulation of microvillus length
0.43	GO:0030855	epithelial cell differentiation

0.70	GO:0005509	calcium ion binding
0.43	GO:0050839	cell adhesion molecule binding

0.56	GO:0005886	plasma membrane
0.46	GO:0089717	spanning component of membrane
0.45	GO:0005902	microvillus
0.44	GO:0005903	brush border
0.43	GO:0045177	apical part of cell
0.42	GO:0120038	plasma membrane bounded cell projection part

tr|T1ENR7|T1ENR7_HELRO
Uncharacterized protein
Search

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.39	GO:0032501	multicellular organismal process
0.38	GO:0048856	anatomical structure development
0.37	GO:0007267	cell-cell signaling
0.37	GO:0060471	cortical granule exocytosis
0.36	GO:0007010	cytoskeleton organization
0.35	GO:0001667	ameboidal-type cell migration
0.35	GO:0007163	establishment or maintenance of cell polarity
0.34	GO:0007017	microtubule-based process
0.34	GO:0050982	detection of mechanical stimulus

0.70	GO:0005509	calcium ion binding
0.34	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0016791	phosphatase activity

0.55	GO:0005886	plasma membrane
0.36	GO:0005911	cell-cell junction
0.35	GO:0005912	adherens junction
0.35	GO:0030175	filopodium
0.35	GO:0030027	lamellipodium
0.35	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0005615	extracellular space
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.33

EC:3.1.3 EC:3.1.3.41

GO:0016791

tr|T1ENR8|T1ENR8_HELRO
Uncharacterized protein
Search

tr|T1ENR9|T1ENR9_HELRO
Uncharacterized protein
Search

tr|T1ENS0|T1ENS0_HELRO
Uncharacterized protein
Search

0.76	GO:0006335	DNA replication-dependent nucleosome assembly
0.52	GO:0009934	regulation of meristem structural organization
0.51	GO:0031507	heterochromatin assembly
0.51	GO:0010026	trichome differentiation
0.49	GO:0048366	leaf development
0.49	GO:0009555	pollen development
0.48	GO:0006281	DNA repair
0.48	GO:0008283	cell proliferation
0.48	GO:0045787	positive regulation of cell cycle
0.44	GO:0007049	cell cycle

0.77	GO:0070087	chromo shadow domain binding
0.63	GO:0042802	identical protein binding
0.41	GO:0043531	ADP binding
0.39	GO:0051213	dioxygenase activity
0.37	GO:0003682	chromatin binding
0.37	GO:0051082	unfolded protein binding

0.85	GO:0033186	CAF-1 complex
0.64	GO:0000790	nuclear chromatin
0.30	GO:0016020	membrane

tr|T1ENS1|T1ENS1_HELRO
Uncharacterized protein
Search

tr|T1ENS2|T1ENS2_HELRO
Uncharacterized protein
Search

tr|T1ENS3|T1ENS3_HELRO
Uncharacterized protein
Search

tr|T1ENS4|T1ENS4_HELRO
Uncharacterized protein
Search

tr|T1ENS5|T1ENS5_HELRO
Uncharacterized protein
Search

0.59

GO:0051603

proteolysis involved in cellular protein catabolic process

0.63	GO:0070003	threonine-type peptidase activity
0.54	GO:0004175	endopeptidase activity

0.65	GO:0019773	proteasome core complex, alpha-subunit complex
0.43	GO:0005737	cytoplasm

tr|T1ENS6|T1ENS6_HELRO
Uncharacterized protein
Search

0.73	GO:0030036	actin cytoskeleton organization
0.50	GO:0022604	regulation of cell morphogenesis
0.48	GO:0065008	regulation of biological quality
0.42	GO:0097435	supramolecular fiber organization
0.41	GO:1990504	dense core granule exocytosis
0.40	GO:0048489	synaptic vesicle transport
0.40	GO:0099504	synaptic vesicle cycle
0.40	GO:0099643	signal release from synapse
0.40	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.40	GO:0032273	positive regulation of protein polymerization

0.77	GO:0017048	Rho GTPase binding
0.73	GO:0003779	actin binding
0.39	GO:0008017	microtubule binding
0.35	GO:0004842	ubiquitin-protein transferase activity
0.35	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.34	GO:0052861	glucan endo-1,3-beta-glucanase activity, C-3 substituted reducing group
0.32	GO:0008289	lipid binding
0.32	GO:0020037	heme binding
0.31	GO:0016491	oxidoreductase activity
0.31	GO:0046872	metal ion binding

0.41	GO:0005884	actin filament
0.40	GO:0098793	presynapse
0.32	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.35	EC:5.2.1.8	GO:0003755
0.35	KEGG:R03876	GO:0004842

tr|T1ENS7|T1ENS7_HELRO
Uncharacterized protein
Search

tr|T1ENS8|T1ENS8_HELRO
Uncharacterized protein
Search

0.33

GO:0003723

RNA binding

0.30

GO:0044425

membrane part

tr|T1ENS9|T1ENS9_HELRO
Uncharacterized protein
Search

tr|T1ENT0|T1ENT0_HELRO
Uncharacterized protein
Search

tr|T1ENT1|T1ENT1_HELRO
Uncharacterized protein
Search

tr|T1ENT2|T1ENT2_HELRO
Uncharacterized protein
Search

tr|T1ENT3|T1ENT3_HELRO
Uncharacterized protein
Search

tr|T1ENT4|T1ENT4_HELRO
Uncharacterized protein
Search

tr|T1ENT5|T1ENT5_HELRO
Uncharacterized protein
Search

tr|T1ENT6|T1ENT6_HELRO
Uncharacterized protein
Search

0.45	GO:0007165	signal transduction
0.39	GO:0034220	ion transmembrane transport
0.39	GO:1903506	regulation of nucleic acid-templated transcription
0.39	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.39	GO:0010468	regulation of gene expression
0.38	GO:0006468	protein phosphorylation

0.48	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.44	GO:0005230	extracellular ligand-gated ion channel activity
0.43	GO:0030246	carbohydrate binding
0.42	GO:0004888	transmembrane signaling receptor activity
0.40	GO:0046872	metal ion binding
0.38	GO:0004672	protein kinase activity
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding

0.40	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|T1ENT7|T1ENT7_HELRO
Uncharacterized protein
Search

tr|T1ENT8|T1ENT8_HELRO
Uncharacterized protein
Search

tr|T1ENT9|T1ENT9_HELRO
Uncharacterized protein
Search

0.77

GO:0035725

sodium ion transmembrane transport

0.81

GO:0005272

sodium channel activity

0.30

GO:0031224

intrinsic component of membrane

tr|T1ENU0|T1ENU0_HELRO
Uncharacterized protein
Search

0.60	GO:0006508	proteolysis
0.58	GO:0007229	integrin-mediated signaling pathway
0.36	GO:0051704	multi-organism process
0.36	GO:0060467	negative regulation of fertilization
0.36	GO:0032501	multicellular organismal process
0.36	GO:0022414	reproductive process
0.35	GO:0009593	detection of chemical stimulus
0.35	GO:0007186	G-protein coupled receptor signaling pathway
0.35	GO:0001775	cell activation
0.33	GO:0016310	phosphorylation

0.70	GO:0004222	metalloendopeptidase activity
0.53	GO:0046872	metal ion binding
0.37	GO:0090729	toxin activity
0.37	GO:0017124	SH3 domain binding
0.35	GO:0004984	olfactory receptor activity
0.33	GO:0016301	kinase activity

0.41	GO:0005739	mitochondrion
0.40	GO:0005886	plasma membrane
0.36	GO:0005794	Golgi apparatus
0.34	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.70

GO:0004222

tr|T1ENU1|T1ENU1_HELRO
Uncharacterized protein
Search

tr|T1ENU2|T1ENU2_HELRO
Uncharacterized protein
Search

tr|T1ENU3|T1ENU3_HELRO
Uncharacterized protein
Search

0.52	GO:0071897	DNA biosynthetic process
0.51	GO:0006260	DNA replication
0.45	GO:0006357	regulation of transcription by RNA polymerase II
0.43	GO:0016567	protein ubiquitination
0.42	GO:0023051	regulation of signaling
0.42	GO:0007039	protein catabolic process in the vacuole
0.41	GO:0022616	DNA strand elongation
0.41	GO:0042149	cellular response to glucose starvation
0.41	GO:0080009	mRNA methylation
0.41	GO:0007018	microtubule-based movement

0.54	GO:0003887	DNA-directed DNA polymerase activity
0.45	GO:0003677	DNA binding
0.44	GO:0004842	ubiquitin-protein transferase activity
0.43	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.41	GO:0004483	mRNA (nucleoside-2'-O-)-methyltransferase activity
0.41	GO:0003777	microtubule motor activity
0.40	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.40	GO:0051015	actin filament binding
0.40	GO:0008270	zinc ion binding
0.40	GO:0019888	protein phosphatase regulator activity

0.43	GO:0043625	delta DNA polymerase complex
0.42	GO:0030286	dynein complex
0.41	GO:0000164	protein phosphatase type 1 complex
0.39	GO:0005773	vacuole
0.30	GO:0031224	intrinsic component of membrane

0.54	EC:2.7.7.7	GO:0003887
0.44	KEGG:R03876	GO:0004842

tr|T1ENU4|T1ENU4_HELRO
Uncharacterized protein
Search

tr|T1ENU5|T1ENU5_HELRO
Uncharacterized protein
Search

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.41	GO:0007275	multicellular organism development
0.39	GO:1990709	presynaptic active zone organization
0.39	GO:2000807	regulation of synaptic vesicle clustering
0.39	GO:0099172	presynapse organization
0.39	GO:0007267	cell-cell signaling
0.39	GO:0007610	behavior
0.39	GO:0050805	negative regulation of synaptic transmission
0.37	GO:0060471	cortical granule exocytosis
0.36	GO:0050821	protein stabilization

0.70	GO:0005509	calcium ion binding
0.39	GO:0045295	gamma-catenin binding
0.36	GO:0004022	alcohol dehydrogenase (NAD) activity
0.35	GO:0032794	GTPase activating protein binding
0.35	GO:0030506	ankyrin binding
0.34	GO:0008013	beta-catenin binding
0.34	GO:0045296	cadherin binding
0.34	GO:0042802	identical protein binding
0.33	GO:0008233	peptidase activity

0.56	GO:0005886	plasma membrane
0.37	GO:0005911	cell-cell junction
0.37	GO:0098562	cytoplasmic side of membrane
0.36	GO:0012505	endomembrane system
0.35	GO:0120025	plasma membrane bounded cell projection
0.35	GO:0032421	stereocilium bundle
0.35	GO:0045177	apical part of cell
0.34	GO:0005615	extracellular space
0.34	GO:0043226	organelle
0.34	GO:0098857	membrane microdomain

0.36

EC:1.1.1.1

GO:0004022

tr|T1ENU6|T1ENU6_HELRO
Uncharacterized protein
Search

0.61	GO:0006508	proteolysis
0.51	GO:0007596	blood coagulation
0.43	GO:0043010	camera-type eye development
0.38	GO:1904627	response to phorbol 13-acetate 12-myristate
0.37	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan
0.35	GO:0044537	regulation of circulating fibrinogen levels
0.35	GO:1901552	positive regulation of endothelial cell development
0.35	GO:1903140	regulation of establishment of endothelial barrier
0.35	GO:0030195	negative regulation of blood coagulation
0.35	GO:0050728	negative regulation of inflammatory response

0.69	GO:0004252	serine-type endopeptidase activity
0.49	GO:0005509	calcium ion binding
0.36	GO:0008201	heparin binding
0.35	GO:0005044	scavenger receptor activity
0.33	GO:0022848	acetylcholine-gated cation-selective channel activity
0.33	GO:0099600	transmembrane receptor activity
0.32	GO:0003677	DNA binding

0.49	GO:0005576	extracellular region
0.40	GO:0005783	endoplasmic reticulum
0.35	GO:0046658	anchored component of plasma membrane
0.35	GO:0019897	extrinsic component of plasma membrane
0.34	GO:0005794	Golgi apparatus
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0031984	organelle subcompartment
0.33	GO:0045211	postsynaptic membrane
0.33	GO:0030054	cell junction
0.32	GO:0005634	nucleus

0.69

GO:0004252

tr|T1ENU7|T1ENU7_HELRO
Uncharacterized protein
Search

tr|T1ENU8|T1ENU8_HELRO
Uncharacterized protein
Search

0.52	Glucose dehydrogenase [acceptor]

0.53	GO:0055114	oxidation-reduction process
0.34	GO:0019285	glycine betaine biosynthetic process from choline
0.33	GO:0005975	carbohydrate metabolic process

0.66	GO:0050660	flavin adenine dinucleotide binding
0.65	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors
0.34	GO:0016874	ligase activity
0.33	GO:0046593	mandelonitrile lyase activity

0.33	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.65

EC:1.1

GO:0016614

tr|T1ENU9|T1ENU9_HELRO
Uncharacterized protein
Search

tr|T1ENV0|T1ENV0_HELRO
Uncharacterized protein
Search

0.47	GO:0014912	negative regulation of smooth muscle cell migration
0.47	GO:0014911	positive regulation of smooth muscle cell migration
0.46	GO:0021591	ventricular system development
0.34	GO:0030154	cell differentiation
0.33	GO:0007179	transforming growth factor beta receptor signaling pathway
0.32	GO:2001141	regulation of RNA biosynthetic process
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.47	GO:0030215	semaphorin receptor binding
0.32	GO:0003700	DNA binding transcription factor activity

0.42	GO:0005794	Golgi apparatus
0.39	GO:0005886	plasma membrane
0.33	GO:0005667	transcription factor complex
0.30	GO:0016021	integral component of membrane

tr|T1ENV1|T1ENV1_HELRO
Uncharacterized protein
Search

0.10	Semaphorin

0.39	GO:0007275	multicellular organism development
0.39	GO:0050919	negative chemotaxis
0.37	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.37	GO:0000904	cell morphogenesis involved in differentiation
0.37	GO:0008037	cell recognition
0.37	GO:0120036	plasma membrane bounded cell projection organization
0.36	GO:0016358	dendrite development
0.36	GO:0071526	semaphorin-plexin signaling pathway
0.36	GO:2000020	positive regulation of male gonad development
0.36	GO:0051960	regulation of nervous system development

0.39	GO:0038191	neuropilin binding
0.37	GO:0030215	semaphorin receptor binding
0.36	GO:0045499	chemorepellent activity
0.33	GO:0008201	heparin binding

0.37	GO:0005615	extracellular space
0.36	GO:0005887	integral component of plasma membrane
0.34	GO:0044297	cell body
0.34	GO:0030424	axon
0.33	GO:0005829	cytosol
0.33	GO:1903561	extracellular vesicle
0.32	GO:0005783	endoplasmic reticulum

tr|T1ENV2|T1ENV2_HELRO
Uncharacterized protein
Search

0.39	GO:0090597	nematode male tail mating organ morphogenesis
0.37	GO:0007399	nervous system development
0.37	GO:0030154	cell differentiation
0.35	GO:0050919	negative chemotaxis
0.34	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.34	GO:0120036	plasma membrane bounded cell projection organization
0.33	GO:0006928	movement of cell or subcellular component

0.39	GO:0030215	semaphorin receptor binding
0.35	GO:0038191	neuropilin binding

0.37	GO:0005887	integral component of plasma membrane
0.34	GO:0005615	extracellular space

tr|T1ENV3|T1ENV3_HELRO
Uncharacterized protein
Search

tr|T1ENV4|T1ENV4_HELRO
Uncharacterized protein
Search

tr|T1ENV5|T1ENV5_HELRO
Uncharacterized protein
Search

tr|T1ENV6|T1ENV6_HELRO
Uncharacterized protein
Search

0.63	GO:0001558	regulation of cell growth
0.46	GO:0030216	keratinocyte differentiation
0.46	GO:0018149	peptide cross-linking
0.45	GO:0030001	metal ion transport
0.42	GO:0007341	penetration of zona pellucida
0.41	GO:0007339	binding of sperm to zona pellucida
0.41	GO:0030317	flagellated sperm motility
0.39	GO:0046916	cellular transition metal ion homeostasis
0.39	GO:0007010	cytoskeleton organization
0.35	GO:0005975	carbohydrate metabolic process

0.65	GO:0005520	insulin-like growth factor binding
0.42	GO:0005198	structural molecule activity
0.41	GO:0046872	metal ion binding
0.38	GO:0004563	beta-N-acetylhexosaminidase activity
0.37	GO:0005544	calcium-dependent phospholipid binding
0.37	GO:0030246	carbohydrate binding

0.54	GO:0005576	extracellular region
0.49	GO:0005882	intermediate filament
0.46	GO:0001533	cornified envelope
0.39	GO:0005741	mitochondrial outer membrane
0.30	GO:0031224	intrinsic component of membrane

0.38

EC:3.2.1.52

GO:0004563

tr|T1ENV7|T1ENV7_HELRO
Uncharacterized protein
Search

tr|T1ENV8|T1ENV8_HELRO
Uncharacterized protein
Search

tr|T1ENV9|T1ENV9_HELRO
Uncharacterized protein
Search

tr|T1ENW0|T1ENW0_HELRO
Uncharacterized protein
Search

0.34

GO:0006334

nucleosome assembly

0.33	GO:0102205	cholesterol allpha-glucosyltransferase activity
0.33	GO:0102202	soladodine glucosyltransferase activity
0.33	GO:0102203	brassicasterol glucosyltransferase activity
0.33	GO:0016906	sterol 3-beta-glucosyltransferase activity
0.32	GO:0003677	DNA binding

0.69	GO:0005856	cytoskeleton
0.34	GO:0000786	nucleosome
0.33	GO:0005634	nucleus

0.33

EC:2.4.1.173

GO:0102202

tr|T1ENW1|T1ENW1_HELRO
Uncharacterized protein
Search

tr|T1ENW2|T1ENW2_HELRO
Uncharacterized protein
Search

tr|T1ENW3|T1ENW3_HELRO
Uncharacterized protein
Search

tr|T1ENW4|T1ENW4_HELRO
Uncharacterized protein
Search

tr|T1ENW5|T1ENW5_HELRO
Uncharacterized protein
Search

tr|T1ENW6|T1ENW6_HELRO
Uncharacterized protein
Search

tr|T1ENW7|T1ENW7_HELRO
Uncharacterized protein
Search

0.43	GO:0006468	protein phosphorylation
0.40	GO:0051726	regulation of cell cycle
0.39	GO:0080090	regulation of primary metabolic process
0.39	GO:0060255	regulation of macromolecule metabolic process
0.39	GO:0031323	regulation of cellular metabolic process
0.39	GO:0051171	regulation of nitrogen compound metabolic process
0.38	GO:0009889	regulation of biosynthetic process
0.37	GO:0051338	regulation of transferase activity
0.37	GO:0000398	mRNA splicing, via spliceosome
0.36	GO:0006366	transcription by RNA polymerase II

0.43	GO:0004672	protein kinase activity
0.41	GO:0003676	nucleic acid binding
0.39	GO:0032559	adenyl ribonucleotide binding
0.39	GO:0008144	drug binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0019901	protein kinase binding
0.38	GO:0001085	RNA polymerase II transcription factor binding
0.37	GO:0003700	DNA binding transcription factor activity
0.37	GO:0003682	chromatin binding
0.36	GO:0016849	phosphorus-oxygen lyase activity

0.42	GO:0005634	nucleus
0.36	GO:0031461	cullin-RING ubiquitin ligase complex
0.36	GO:0005667	transcription factor complex
0.36	GO:0005829	cytosol
0.36	GO:0044446	intracellular organelle part
0.35	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016020	membrane

0.36

EC:4.6

GO:0016849

tr|T1ENW8|T1ENW8_HELRO
Uncharacterized protein
Search

tr|T1ENW9|T1ENW9_HELRO
Uncharacterized protein
Search

tr|T1ENX0|T1ENX0_HELRO
Uncharacterized protein
Search

tr|T1ENX1|T1ENX1_HELRO
Uncharacterized protein
Search

tr|T1ENX2|T1ENX2_HELRO
Uncharacterized protein
Search

tr|T1ENX3|T1ENX3_HELRO
Uncharacterized protein
Search

tr|T1ENX4|T1ENX4_HELRO
Uncharacterized protein
Search

tr|T1ENX5|T1ENX5_HELRO
Uncharacterized protein
Search

tr|T1ENX6|T1ENX6_HELRO
Uncharacterized protein
Search

tr|T1ENX7|T1ENX7_HELRO
Uncharacterized protein
Search

tr|T1ENX8|T1ENX8_HELRO
Uncharacterized protein
Search

tr|T1ENX9|T1ENX9_HELRO
Uncharacterized protein
Search

tr|T1ENY0|T1ENY0_HELRO
Uncharacterized protein
Search

tr|T1ENY1|T1ENY1_HELRO
Uncharacterized protein
Search

tr|T1ENY3|T1ENY3_HELRO
Uncharacterized protein
Search

tr|T1ENY4|T1ENY4_HELRO
Uncharacterized protein
Search

tr|T1ENY5|T1ENY5_HELRO
ATP-dependent DNA helicase
Search

0.10	ATP-dependent DNA helicase

0.86	GO:0044806	G-quadruplex DNA unwinding
0.86	GO:0032211	negative regulation of telomere maintenance via telomerase
0.85	GO:0051974	negative regulation of telomerase activity
0.82	GO:0000002	mitochondrial genome maintenance
0.78	GO:0000723	telomere maintenance
0.70	GO:0032508	DNA duplex unwinding
0.66	GO:0006260	DNA replication
0.65	GO:0006310	DNA recombination
0.65	GO:0006281	DNA repair

0.86	GO:0010521	telomerase inhibitor activity
0.81	GO:0043141	ATP-dependent 5'-3' DNA helicase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.74	GO:0005657	replication fork
0.61	GO:0005634	nucleus
0.61	GO:0005739	mitochondrion

0.81

EC:3.6.1

GO:0043141

tr|T1ENY6|T1ENY6_HELRO
Uncharacterized protein
Search

tr|T1ENY7|T1ENY7_HELRO
Uncharacterized protein
Search

0.69	GO:0007186	G-protein coupled receptor signaling pathway
0.50	GO:1904385	cellular response to angiotensin
0.49	GO:0019229	regulation of vasoconstriction
0.36	GO:1902608	positive regulation of large conductance calcium-activated potassium channel activity
0.35	GO:0043327	chemotaxis to cAMP
0.35	GO:0070098	chemokine-mediated signaling pathway
0.35	GO:0099120	socially cooperative development
0.34	GO:0030041	actin filament polymerization
0.34	GO:0030010	establishment of cell polarity
0.34	GO:0031175	neuron projection development

0.70	GO:0004930	G-protein coupled receptor activity
0.59	GO:0001653	peptide receptor activity
0.39	GO:0042277	peptide binding
0.35	GO:0042562	hormone binding
0.35	GO:0004896	cytokine receptor activity
0.34	GO:0008270	zinc ion binding
0.34	GO:0003779	actin binding
0.34	GO:0003774	motor activity
0.34	GO:0003676	nucleic acid binding
0.33	GO:0003700	DNA binding transcription factor activity

0.40	GO:0009986	cell surface
0.37	GO:0005887	integral component of plasma membrane
0.34	GO:0005737	cytoplasm
0.34	GO:0017053	transcriptional repressor complex
0.34	GO:0016459	myosin complex
0.34	GO:0005634	nucleus

0.32

GO:0016491

tr|T1ENY8|T1ENY8_HELRO
Uncharacterized protein
Search

tr|T1ENY9|T1ENY9_HELRO
Uncharacterized protein
Search

tr|T1ENZ0|T1ENZ0_HELRO
Uncharacterized protein
Search

0.46	GO:0042026	protein refolding
0.39	GO:0098664	G-protein coupled serotonin receptor signaling pathway
0.39	GO:0045944	positive regulation of transcription by RNA polymerase II
0.39	GO:0060195	negative regulation of antisense RNA transcription
0.39	GO:2001208	negative regulation of transcription elongation by RNA polymerase I
0.39	GO:0090262	regulation of transcription-coupled nucleotide-excision repair
0.39	GO:2001209	positive regulation of transcription elongation from RNA polymerase I promoter
0.38	GO:0006396	RNA processing
0.38	GO:2000232	regulation of rRNA processing
0.38	GO:0006904	vesicle docking involved in exocytosis

0.40	GO:0030554	adenyl nucleotide binding
0.40	GO:0032555	purine ribonucleotide binding
0.40	GO:0008144	drug binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0099589	serotonin receptor activity
0.39	GO:0005515	protein binding
0.39	GO:0003723	RNA binding
0.39	GO:0099528	G-protein coupled neurotransmitter receptor activity
0.39	GO:0008227	G-protein coupled amine receptor activity
0.38	GO:0000991	transcription factor activity, core RNA polymerase II binding

0.44	GO:0005634	nucleus
0.41	GO:0031974	membrane-enclosed lumen
0.39	GO:0043234	protein complex
0.38	GO:0030686	90S preribosome
0.38	GO:0005732	small nucleolar ribonucleoprotein complex
0.38	GO:0033553	rDNA heterochromatin
0.38	GO:0020011	apicoplast
0.36	GO:0031248	protein acetyltransferase complex
0.36	GO:1905368	peptidase complex
0.35	GO:0005829	cytosol

0.35

GO:0016773

tr|T1ENZ1|T1ENZ1_HELRO
Uncharacterized protein
Search

tr|T1ENZ2|T1ENZ2_HELRO
Uncharacterized protein
Search

tr|T1ENZ3|T1ENZ3_HELRO
Uncharacterized protein
Search

0.25	Miro domain-containing protein C1orf89

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0032553	ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

tr|T1ENZ4|T1ENZ4_HELRO
Uncharacterized protein
Search

tr|T1ENZ5|T1ENZ5_HELRO
Uncharacterized protein
Search

tr|T1ENZ6|T1ENZ6_HELRO
Uncharacterized protein
Search

tr|T1ENZ7|T1ENZ7_HELRO
Uncharacterized protein
Search

tr|T1ENZ8|T1ENZ8_HELRO
Uncharacterized protein
Search

tr|T1ENZ9|T1ENZ9_HELRO
Uncharacterized protein
Search

tr|T1EP00|T1EP00_HELRO
Uncharacterized protein
Search

0.59	GO:0016567	protein ubiquitination
0.59	GO:0006886	intracellular protein transport

0.67

GO:0008536

Ran GTPase binding

0.53

GO:0005634

nucleus

tr|T1EP01|T1EP01_HELRO
Uncharacterized protein
Search

tr|T1EP02|T1EP02_HELRO
Uncharacterized protein
Search

tr|T1EP03|T1EP03_HELRO
Uncharacterized protein
Search

tr|T1EP04|T1EP04_HELRO
Uncharacterized protein
Search

tr|T1EP05|T1EP05_HELRO
Uncharacterized protein
Search

tr|T1EP06|T1EP06_HELRO
Uncharacterized protein
Search

tr|T1EP07|T1EP07_HELRO
Uncharacterized protein
Search

tr|T1EP08|T1EP08_HELRO
Uncharacterized protein
Search

tr|T1EP09|T1EP09_HELRO
Uncharacterized protein
Search

tr|T1EP10|T1EP10_HELRO
Uncharacterized protein
Search

tr|T1EP11|T1EP11_HELRO
Uncharacterized protein
Search

tr|T1EP12|T1EP12_HELRO
Uncharacterized protein
Search

tr|T1EP13|T1EP13_HELRO
Uncharacterized protein
Search

tr|T1EP14|T1EP14_HELRO
Uncharacterized protein
Search

tr|T1EP15|T1EP15_HELRO
Uncharacterized protein
Search

0.69	Phosphatidylcholine-sterol acyltransferase

0.63	GO:0006629	lipid metabolic process
0.32	GO:0006468	protein phosphorylation
0.32	GO:0055085	transmembrane transport

0.74	GO:0008374	O-acyltransferase activity
0.32	GO:0004672	protein kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0042626	ATPase activity, coupled to transmembrane movement of substances

0.30

GO:0044425

membrane part

0.74

GO:0008374

tr|T1EP16|T1EP16_HELRO
Uncharacterized protein
Search

0.61	GO:0006508	proteolysis
0.46	GO:0045214	sarcomere organization
0.42	GO:0051493	regulation of cytoskeleton organization
0.38	GO:0014718	positive regulation of satellite cell activation involved in skeletal muscle regeneration
0.38	GO:0033234	negative regulation of protein sumoylation
0.38	GO:0070315	G1 to G0 transition involved in cell differentiation
0.37	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol
0.37	GO:2001015	negative regulation of skeletal muscle cell differentiation
0.37	GO:0043066	negative regulation of apoptotic process
0.37	GO:0071472	cellular response to salt stress

0.82	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.56	GO:0005509	calcium ion binding
0.39	GO:0055103	ligase regulator activity
0.38	GO:0031432	titin binding
0.38	GO:0008307	structural constituent of muscle
0.37	GO:0032947	protein complex scaffold activity
0.37	GO:0031402	sodium ion binding
0.33	GO:0008017	microtubule binding
0.33	GO:0008270	zinc ion binding
0.33	GO:0008236	serine-type peptidase activity

0.45	GO:0005622	intracellular
0.35	GO:0030315	T-tubule
0.35	GO:0099512	supramolecular fiber
0.34	GO:0043226	organelle
0.34	GO:0043234	protein complex
0.33	GO:0043025	neuronal cell body
0.33	GO:0009986	cell surface
0.30	GO:0016021	integral component of membrane

tr|T1EP17|T1EP17_HELRO
Uncharacterized protein
Search

tr|T1EP18|T1EP18_HELRO
Uncharacterized protein
Search

tr|T1EP19|T1EP19_HELRO
Uncharacterized protein
Search

tr|T1EP20|T1EP20_HELRO
Uncharacterized protein
Search

UBE2M

0.73	Ubiquitin-conjugating enzyme m

0.50	GO:0045116	protein neddylation
0.45	GO:0016567	protein ubiquitination
0.39	GO:0043525	positive regulation of neuron apoptotic process
0.35	GO:0038061	NIK/NF-kappaB signaling
0.34	GO:0007179	transforming growth factor beta receptor signaling pathway
0.34	GO:0043687	post-translational protein modification

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0019788	NEDD8 transferase activity
0.46	GO:0004842	ubiquitin-protein transferase activity
0.42	GO:0031625	ubiquitin protein ligase binding
0.42	GO:0061659	ubiquitin-like protein ligase activity
0.39	GO:0016874	ligase activity
0.32	GO:0003676	nucleic acid binding

0.36	GO:0070062	extracellular exosome
0.35	GO:0005737	cytoplasm
0.33	GO:0005654	nucleoplasm

0.39	EC:6	GO:0016874
0.46	KEGG:R03876	GO:0004842

tr|T1EP21|T1EP21_HELRO
Uncharacterized protein
Search

tr|T1EP22|T1EP22_HELRO
Uncharacterized protein
Search

0.39	GO:0045722	positive regulation of gluconeogenesis
0.39	GO:0000429	carbon catabolite regulation of transcription from RNA polymerase II promoter
0.39	GO:0006508	proteolysis
0.38	GO:0015976	carbon utilization
0.37	GO:0006629	lipid metabolic process
0.37	GO:0006468	protein phosphorylation
0.36	GO:0030001	metal ion transport
0.36	GO:0006351	transcription, DNA-templated
0.36	GO:0045454	cell redox homeostasis
0.36	GO:0005975	carbohydrate metabolic process

0.44	GO:0016757	transferase activity, transferring glycosyl groups
0.39	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.39	GO:0140096	catalytic activity, acting on a protein
0.38	GO:0016787	hydrolase activity
0.38	GO:0030151	molybdenum ion binding
0.38	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.37	GO:0008270	zinc ion binding
0.37	GO:0050662	coenzyme binding
0.37	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.37	GO:0008144	drug binding

0.37	GO:0005634	nucleus
0.36	GO:0043190	ATP-binding cassette (ABC) transporter complex

0.44

GO:0016757

tr|T1EP23|T1EP23_HELRO
Uncharacterized protein
Search

tr|T1EP24|T1EP24_HELRO
Uncharacterized protein
Search

0.30

GO:0044425

membrane part

tr|T1EP25|T1EP25_HELRO
Uncharacterized protein
Search

tr|T1EP26|T1EP26_HELRO
Uncharacterized protein
Search

0.59	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.56	GO:0048514	blood vessel morphogenesis
0.55	GO:0045930	negative regulation of mitotic cell cycle
0.55	GO:0042742	defense response to bacterium
0.55	GO:0006915	apoptotic process

0.60

GO:0043027

cysteine-type endopeptidase inhibitor activity involved in apoptotic process

0.56	GO:0005581	collagen trimer
0.50	GO:0005576	extracellular region
0.45	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016020	membrane

tr|T1EP27|T1EP27_HELRO
Uncharacterized protein
Search

tr|T1EP28|T1EP28_HELRO
Uncharacterized protein
Search

0.73	GO:0007202	activation of phospholipase C activity
0.72	GO:0050901	leukocyte tethering or rolling
0.72	GO:0002092	positive regulation of receptor internalization
0.70	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.69	GO:0070555	response to interleukin-1
0.61	GO:0030029	actin filament-based process
0.52	GO:0007165	signal transduction

0.74	GO:0033691	sialic acid binding
0.73	GO:0043274	phospholipase binding
0.71	GO:0070492	oligosaccharide binding
0.65	GO:0005509	calcium ion binding
0.58	GO:0004888	transmembrane signaling receptor activity

0.68	GO:0005901	caveola
0.66	GO:0005905	clathrin-coated pit
0.66	GO:0030863	cortical cytoskeleton
0.65	GO:0048471	perinuclear region of cytoplasm
0.61	GO:0005615	extracellular space
0.56	GO:0005887	integral component of plasma membrane

tr|T1EP29|T1EP29_HELRO
Uncharacterized protein
Search

0.65	GO:0007155	cell adhesion
0.59	GO:0007202	activation of phospholipase C activity
0.58	GO:0045123	cellular extravasation
0.58	GO:0002092	positive regulation of receptor internalization
0.57	GO:0070555	response to interleukin-1
0.52	GO:1905226	regulation of adhesion of symbiont to host epithelial cell
0.51	GO:0030029	actin filament-based process
0.51	GO:0043152	induction of bacterial agglutination
0.51	GO:0052405	negative regulation by host of symbiont molecular function
0.50	GO:0043129	surfactant homeostasis

0.60	GO:0033691	sialic acid binding
0.59	GO:0043274	phospholipase binding
0.58	GO:0070492	oligosaccharide binding
0.49	GO:0004888	transmembrane signaling receptor activity
0.49	GO:0005509	calcium ion binding
0.40	GO:0042802	identical protein binding
0.36	GO:0001530	lipopolysaccharide binding
0.35	GO:0048029	monosaccharide binding
0.35	GO:0005507	copper ion binding
0.34	GO:0004222	metalloendopeptidase activity

0.56	GO:0005901	caveola
0.56	GO:0005581	collagen trimer
0.54	GO:0005905	clathrin-coated pit
0.54	GO:0030863	cortical cytoskeleton
0.54	GO:0048471	perinuclear region of cytoplasm
0.52	GO:0005615	extracellular space
0.48	GO:0005887	integral component of plasma membrane
0.37	GO:0005578	proteinaceous extracellular matrix
0.36	GO:0005771	multivesicular body
0.36	GO:0005791	rough endoplasmic reticulum

0.34

GO:0004222

tr|T1EP30|T1EP30_HELRO
Uncharacterized protein
Search

0.49	GO:0016192	vesicle-mediated transport
0.49	GO:0006886	intracellular protein transport
0.49	GO:0043666	regulation of phosphoprotein phosphatase activity
0.41	GO:2000002	negative regulation of DNA damage checkpoint
0.39	GO:0031156	regulation of sorocarp development
0.39	GO:0007020	microtubule nucleation
0.38	GO:0051640	organelle localization
0.38	GO:0006366	transcription by RNA polymerase II
0.38	GO:0006470	protein dephosphorylation
0.38	GO:0032107	regulation of response to nutrient levels

0.49	GO:0019888	protein phosphatase regulator activity
0.39	GO:0005515	protein binding
0.37	GO:0016307	phosphatidylinositol phosphate kinase activity
0.37	GO:0046872	metal ion binding
0.37	GO:0017076	purine nucleotide binding
0.37	GO:0032553	ribonucleotide binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0008144	drug binding
0.36	GO:0030248	cellulose binding
0.36	GO:0003676	nucleic acid binding

0.58	GO:0030124	AP-4 adaptor complex
0.51	GO:0030289	protein phosphatase 4 complex
0.41	GO:0005634	nucleus
0.39	GO:0005815	microtubule organizing center
0.39	GO:0000922	spindle pole
0.36	GO:0070013	intracellular organelle lumen
0.35	GO:0005881	cytoplasmic microtubule
0.35	GO:0005777	peroxisome
0.35	GO:0000781	chromosome, telomeric region
0.35	GO:0032040	small-subunit processome

0.37

GO:0016307

tr|T1EP31|T1EP31_HELRO
Uncharacterized protein
Search

tr|T1EP32|T1EP32_HELRO
Uncharacterized protein
Search

tr|T1EP33|T1EP33_HELRO
Uncharacterized protein
Search

tr|T1EP34|T1EP34_HELRO
Uncharacterized protein
Search

tr|T1EP35|T1EP35_HELRO
Uncharacterized protein
Search

tr|T1EP36|T1EP36_HELRO
Uncharacterized protein
Search

DUSP14

0.78	Dual specificity protein phosphatase 14

0.78	GO:0000188	inactivation of MAPK activity
0.72	GO:0006470	protein dephosphorylation

0.79	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.78	GO:0033549	MAP kinase phosphatase activity
0.71	GO:0004725	protein tyrosine phosphatase activity

0.38	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.79

GO:0008138

tr|T1EP37|T1EP37_HELRO
Uncharacterized protein
Search

tr|T1EP38|T1EP38_HELRO
Uncharacterized protein
Search

tr|T1EP39|T1EP39_HELRO
Uncharacterized protein
Search

tr|T1EP40|T1EP40_HELRO
Uncharacterized protein
Search

tr|T1EP41|T1EP41_HELRO
Uncharacterized protein
Search

tr|T1EP42|T1EP42_HELRO
Uncharacterized protein
Search

0.51	GO:0006508	proteolysis
0.49	GO:2001141	regulation of RNA biosynthetic process
0.49	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.48	GO:0010468	regulation of gene expression

0.57	GO:0070001	aspartic-type peptidase activity
0.57	GO:0004386	helicase activity
0.54	GO:0004175	endopeptidase activity
0.51	GO:0003676	nucleic acid binding
0.48	GO:0030554	adenyl nucleotide binding
0.47	GO:0097367	carbohydrate derivative binding
0.47	GO:0008144	drug binding
0.47	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0044425

membrane part

tr|T1EP43|T1EP43_HELRO
Uncharacterized protein
Search

tr|T1EP44|T1EP44_HELRO
Uncharacterized protein
Search

tr|T1EP45|T1EP45_HELRO
Uncharacterized protein
Search

tr|T1EP46|T1EP46_HELRO
Uncharacterized protein
Search

tr|T1EP47|T1EP47_HELRO
Transporter
Search

0.38	Transporter

0.76	GO:0006836	neurotransmitter transport
0.56	GO:0003333	amino acid transmembrane transport
0.44	GO:0060012	synaptic transmission, glycinergic
0.43	GO:0015807	L-amino acid transport
0.43	GO:0015893	drug transport
0.42	GO:0015804	neutral amino acid transport
0.42	GO:0099643	signal release from synapse
0.42	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.42	GO:0046717	acid secretion
0.40	GO:0001505	regulation of neurotransmitter levels

0.79	GO:0005328	neurotransmitter:sodium symporter activity
0.58	GO:0005343	organic acid:sodium symporter activity
0.57	GO:0005416	amino acid:cation symporter activity
0.45	GO:0015187	glycine transmembrane transporter activity
0.41	GO:0005308	creatine transmembrane transporter activity
0.39	GO:0015296	anion:cation symporter activity
0.33	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity
0.33	GO:0008270	zinc ion binding
0.33	GO:0004252	serine-type endopeptidase activity
0.32	GO:0005515	protein binding

0.53	GO:0005887	integral component of plasma membrane
0.42	GO:0044456	synapse part
0.40	GO:0097458	neuron part

0.33

GO:0004252

tr|T1EP48|T1EP48_HELRO
Uncharacterized protein
Search

tr|T1EP49|T1EP49_HELRO
Uncharacterized protein
Search

0.51	GO:0006338	chromatin remodeling
0.43	GO:0005987	sucrose catabolic process
0.43	GO:2000219	positive regulation of invasive growth in response to glucose limitation
0.43	GO:0000436	carbon catabolite activation of transcription from RNA polymerase II promoter
0.41	GO:0048856	anatomical structure development
0.41	GO:0006468	protein phosphorylation
0.40	GO:0000724	double-strand break repair via homologous recombination
0.40	GO:0032501	multicellular organismal process
0.39	GO:0018193	peptidyl-amino acid modification
0.38	GO:0051703	intraspecies interaction between organisms

0.45	GO:0008270	zinc ion binding
0.43	GO:0003677	DNA binding
0.43	GO:0015616	DNA translocase activity
0.42	GO:0001102	RNA polymerase II activating transcription factor binding
0.41	GO:0004672	protein kinase activity
0.41	GO:0140110	transcription regulator activity
0.40	GO:0030554	adenyl nucleotide binding
0.40	GO:0097367	carbohydrate derivative binding
0.40	GO:0008144	drug binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding

0.52	GO:0005634	nucleus
0.47	GO:0070013	intracellular organelle lumen
0.46	GO:0005694	chromosome
0.42	GO:0044446	intracellular organelle part
0.39	GO:0005829	cytosol
0.38	GO:1904949	ATPase complex
0.36	GO:0000323	lytic vacuole
0.36	GO:0005768	endosome
0.36	GO:0031248	protein acetyltransferase complex
0.30	GO:0016021	integral component of membrane

0.37

GO:0008233

tr|T1EP50|T1EP50_HELRO
Uncharacterized protein
Search

tr|T1EP51|T1EP51_HELRO
Uncharacterized protein
Search

tr|T1EP52|T1EP52_HELRO
Uncharacterized protein
Search

tr|T1EP53|T1EP53_HELRO
Uncharacterized protein
Search

0.69	GO:0014002	astrocyte development
0.65	GO:0060041	retina development in camera-type eye
0.62	GO:0000904	cell morphogenesis involved in differentiation
0.62	GO:0007601	visual perception
0.58	GO:0040017	positive regulation of locomotion

0.64	GO:0005604	basement membrane
0.30	GO:0044425	membrane part

tr|T1EP54|T1EP54_HELRO
Uncharacterized protein
Search

tr|T1EP55|T1EP55_HELRO
Uncharacterized protein
Search

tr|T1EP56|T1EP56_HELRO
Uncharacterized protein
Search

tr|T1EP57|T1EP57_HELRO
Uncharacterized protein
Search

tr|T1EP58|T1EP58_HELRO
Uncharacterized protein
Search

tr|T1EP59|T1EP59_HELRO
Uncharacterized protein
Search

0.80	GO:0043631	RNA polyadenylation
0.75	GO:0031123	RNA 3'-end processing

0.78	GO:0004652	polynucleotide adenylyltransferase activity
0.58	GO:0003723	RNA binding
0.35	GO:0030554	adenyl nucleotide binding
0.35	GO:0097367	carbohydrate derivative binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0046872	metal ion binding

0.61	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.78

EC:2.7.7.19

GO:0004652

tr|T1EP60|T1EP60_HELRO
Uncharacterized protein
Search

0.46	GO:0045862	positive regulation of proteolysis
0.45	GO:0043085	positive regulation of catalytic activity
0.43	GO:0052547	regulation of peptidase activity
0.41	GO:0010468	regulation of gene expression
0.40	GO:2001141	regulation of RNA biosynthetic process
0.40	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.40	GO:0031288	sorocarp morphogenesis
0.38	GO:0031152	aggregation involved in sorocarp development
0.38	GO:0007346	regulation of mitotic cell cycle
0.38	GO:0043412	macromolecule modification

0.46	GO:0070577	lysine-acetylated histone binding
0.46	GO:0016504	peptidase activator activity
0.46	GO:0070628	proteasome binding
0.44	GO:0030554	adenyl nucleotide binding
0.43	GO:0097367	carbohydrate derivative binding
0.43	GO:0008144	drug binding
0.43	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0043565	sequence-specific DNA binding
0.41	GO:0003700	DNA binding transcription factor activity
0.40	GO:0017111	nucleoside-triphosphatase activity

0.38	GO:0005634	nucleus
0.38	GO:0032991	macromolecular complex
0.37	GO:0015630	microtubule cytoskeleton
0.37	GO:0044430	cytoskeletal part
0.36	GO:0012505	endomembrane system
0.36	GO:0099512	supramolecular fiber
0.36	GO:0005829	cytosol
0.35	GO:0044459	plasma membrane part
0.33	GO:0031967	organelle envelope
0.30	GO:0016021	integral component of membrane

0.40	EC:3.6.1.15	GO:0017111
0.38	KEGG:R03656	GO:0004822

tr|T1EP61|T1EP61_HELRO
Uncharacterized protein
Search

tr|T1EP62|T1EP62_HELRO
Uncharacterized protein
Search

0.25	phosphatidylinositol N-acetylglucosaminyltransferase subunit H-like

0.84

GO:0017176

phosphatidylinositol N-acetylglucosaminyltransferase activity

0.30

GO:0044425

membrane part

0.84

EC:2.4.1.198

GO:0017176

tr|T1EP63|T1EP63_HELRO
Uncharacterized protein
Search

0.56	Clathrin adaptor complex small chain

0.69	GO:0006886	intracellular protein transport
0.69	GO:0016192	vesicle-mediated transport
0.43	GO:0098657	import into cell
0.41	GO:0002119	nematode larval development
0.41	GO:0010171	body morphogenesis
0.40	GO:0009792	embryo development ending in birth or egg hatching
0.35	GO:0032802	low-density lipoprotein particle receptor catabolic process
0.35	GO:0034383	low-density lipoprotein particle clearance
0.35	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.34	GO:0060071	Wnt signaling pathway, planar cell polarity pathway

0.70	GO:0008565	protein transporter activity
0.35	GO:0030276	clathrin binding
0.35	GO:0016787	hydrolase activity
0.34	GO:0098748	endocytic adaptor activity
0.34	GO:0046872	metal ion binding
0.33	GO:0004871	signal transducer activity
0.32	GO:0003677	DNA binding

0.84	GO:0030122	AP-2 adaptor complex
0.35	GO:0036020	endolysosome membrane
0.33	GO:0005829	cytosol
0.33	GO:0031966	mitochondrial membrane
0.30	GO:0016021	integral component of membrane

0.35

GO:0016787

tr|T1EP64|T1EP64_HELRO
Uncharacterized protein
Search

0.76	Blocked early in transport 1

0.30

GO:0044425

membrane part

tr|T1EP65|T1EP65_HELRO
Uncharacterized protein
Search

tr|T1EP66|T1EP66_HELRO
Uncharacterized protein
Search

tr|T1EP67|T1EP67_HELRO
Uncharacterized protein
Search

tr|T1EP68|T1EP68_HELRO
Uncharacterized protein
Search

0.47	GO:0044267	cellular protein metabolic process
0.45	GO:0043043	peptide biosynthetic process
0.44	GO:0036211	protein modification process
0.43	GO:0009059	macromolecule biosynthetic process
0.43	GO:0010467	gene expression
0.42	GO:0006325	chromatin organization
0.40	GO:0022402	cell cycle process
0.39	GO:0000278	mitotic cell cycle
0.39	GO:0016310	phosphorylation
0.39	GO:0065007	biological regulation

0.47	GO:0003735	structural constituent of ribosome
0.42	GO:0140096	catalytic activity, acting on a protein
0.41	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.40	GO:0016301	kinase activity
0.40	GO:0016278	lysine N-methyltransferase activity
0.39	GO:0097367	carbohydrate derivative binding
0.39	GO:0030554	adenyl nucleotide binding
0.39	GO:0008144	drug binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0003676	nucleic acid binding

0.54	GO:0005761	mitochondrial ribosome
0.42	GO:0005634	nucleus
0.40	GO:0034708	methyltransferase complex
0.39	GO:0005667	transcription factor complex
0.37	GO:0031012	extracellular matrix
0.37	GO:0032153	cell division site
0.36	GO:0033202	DNA helicase complex
0.36	GO:0005856	cytoskeleton
0.36	GO:0005887	integral component of plasma membrane
0.35	GO:0000785	chromatin

0.41

GO:0016773

tr|T1EP69|T1EP69_HELRO
Uncharacterized protein
Search

tr|T1EP70|T1EP70_HELRO
Uncharacterized protein
Search

0.60	GO:0005975	carbohydrate metabolic process
0.34	GO:0044248	cellular catabolic process
0.34	GO:1901575	organic substance catabolic process

0.47	GO:0103025	alpha-amylase activity (releasing maltohexaose)
0.47	GO:0004556	alpha-amylase activity
0.45	GO:0047471	maltose alpha-D-glucosyltransferase activity
0.37	GO:0016740	transferase activity
0.37	GO:0032450	maltose alpha-glucosidase activity
0.37	GO:0004558	alpha-1,4-glucosidase activity
0.36	GO:0008788	alpha,alpha-phosphotrehalase activity
0.33	GO:0043169	cation binding

0.32	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

0.47

EC:3.2.1.1

GO:0004556

tr|T1EP71|T1EP71_HELRO
Uncharacterized protein
Search

0.44	GO:2001141	regulation of RNA biosynthetic process
0.44	GO:0006468	protein phosphorylation
0.44	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.44	GO:0010468	regulation of gene expression
0.41	GO:0032502	developmental process
0.41	GO:0043486	histone exchange
0.40	GO:0007049	cell cycle
0.40	GO:0048522	positive regulation of cellular process
0.40	GO:1903286	regulation of potassium ion import
0.40	GO:0022414	reproductive process

0.45	GO:0004674	protein serine/threonine kinase activity
0.45	GO:0140110	transcription regulator activity
0.43	GO:0097367	carbohydrate derivative binding
0.43	GO:0017076	purine nucleotide binding
0.43	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0008144	drug binding
0.41	GO:0005057	signal transducer activity, downstream of receptor
0.41	GO:0003924	GTPase activity
0.40	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.39	GO:0044374	sequence-specific DNA binding, bending

0.42	GO:0005634	nucleus
0.40	GO:0070013	intracellular organelle lumen
0.38	GO:0032153	cell division site
0.38	GO:0043234	protein complex
0.37	GO:0044446	intracellular organelle part
0.37	GO:0005887	integral component of plasma membrane
0.36	GO:0031248	protein acetyltransferase complex
0.36	GO:0043232	intracellular non-membrane-bounded organelle
0.36	GO:1905368	peptidase complex
0.36	GO:0005829	cytosol

0.45

GO:0004674

tr|T1EP72|T1EP72_HELRO
Uncharacterized protein
Search

0.53	GO:0006468	protein phosphorylation
0.43	GO:0071230	cellular response to amino acid stimulus
0.42	GO:0030307	positive regulation of cell growth
0.42	GO:0006030	chitin metabolic process
0.42	GO:0031929	TOR signaling
0.42	GO:0008361	regulation of cell size
0.42	GO:0071902	positive regulation of protein serine/threonine kinase activity
0.41	GO:0009267	cellular response to starvation
0.40	GO:0010506	regulation of autophagy
0.40	GO:0006353	DNA-templated transcription, termination

0.53	GO:0004672	protein kinase activity
0.48	GO:0097367	carbohydrate derivative binding
0.48	GO:0008144	drug binding
0.48	GO:0030554	adenyl nucleotide binding
0.47	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0030674	protein binding, bridging
0.41	GO:0003712	transcription cofactor activity
0.41	GO:0046982	protein heterodimerization activity
0.40	GO:0008186	RNA-dependent ATPase activity
0.38	GO:0004386	helicase activity

0.43	GO:0046695	SLIK (SAGA-like) complex
0.42	GO:0031931	TORC1 complex
0.42	GO:0000124	SAGA complex
0.42	GO:0005669	transcription factor TFIID complex
0.39	GO:0005576	extracellular region
0.35	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|T1EP73|T1EP73_HELRO
Uncharacterized protein
Search

tr|T1EP74|T1EP74_HELRO
Uncharacterized protein
Search

tr|T1EP75|T1EP75_HELRO
Uncharacterized protein
Search

tr|T1EP76|T1EP76_HELRO
Uncharacterized protein
Search

tr|T1EP77|T1EP77_HELRO
Uncharacterized protein
Search

0.78	GO:0043066	negative regulation of apoptotic process
0.44	GO:0006915	apoptotic process

0.40

GO:0005515

protein binding

0.39

GO:0005634

nucleus

tr|T1EP78|T1EP78_HELRO
Uncharacterized protein
Search

0.11	Pleckstrin homology domain-containing family G member 7

0.78	GO:0035023	regulation of Rho protein signal transduction
0.66	GO:0065009	regulation of molecular function
0.57	GO:0035556	intracellular signal transduction

0.78

GO:0005089

Rho guanyl-nucleotide exchange factor activity

0.42	GO:0005622	intracellular
0.30	GO:0044425	membrane part

tr|T1EP79|T1EP79_HELRO
Uncharacterized protein
Search

tr|T1EP80|T1EP80_HELRO
Uncharacterized protein
Search

tr|T1EP81|T1EP81_HELRO
Uncharacterized protein
Search

tr|T1EP82|T1EP82_HELRO
Uncharacterized protein
Search

tr|T1EP83|T1EP83_HELRO
Uncharacterized protein
Search

0.44	GO:0007165	signal transduction
0.39	GO:1903506	regulation of nucleic acid-templated transcription
0.39	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.39	GO:0034220	ion transmembrane transport
0.39	GO:0010468	regulation of gene expression
0.38	GO:0006468	protein phosphorylation

0.48	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.43	GO:0005230	extracellular ligand-gated ion channel activity
0.43	GO:0030246	carbohydrate binding
0.42	GO:0004888	transmembrane signaling receptor activity
0.38	GO:0004672	protein kinase activity
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding

0.40	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|T1EP84|T1EP84_HELRO
Uncharacterized protein
Search

tr|T1EP85|T1EP85_HELRO
Uncharacterized protein
Search

0.42	GO:0036211	protein modification process
0.41	GO:0044267	cellular protein metabolic process
0.40	GO:0055114	oxidation-reduction process
0.39	GO:0016311	dephosphorylation
0.38	GO:0016310	phosphorylation
0.37	GO:0055085	transmembrane transport
0.37	GO:0005975	carbohydrate metabolic process
0.36	GO:0043039	tRNA aminoacylation
0.36	GO:0009057	macromolecule catabolic process
0.36	GO:0006518	peptide metabolic process

0.41	GO:0140096	catalytic activity, acting on a protein
0.41	GO:0016491	oxidoreductase activity
0.40	GO:0016874	ligase activity
0.40	GO:0032555	purine ribonucleotide binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0030554	adenyl nucleotide binding
0.39	GO:0016791	phosphatase activity
0.39	GO:0008144	drug binding
0.38	GO:0016301	kinase activity
0.38	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.41	GO:0043231	intracellular membrane-bounded organelle
0.40	GO:0044446	intracellular organelle part
0.39	GO:0031975	envelope
0.38	GO:0031461	cullin-RING ubiquitin ligase complex
0.38	GO:0031090	organelle membrane
0.37	GO:0044444	cytoplasmic part
0.37	GO:0005576	extracellular region
0.35	GO:0012505	endomembrane system
0.35	GO:0033202	DNA helicase complex
0.34	GO:0043232	intracellular non-membrane-bounded organelle

0.41

GO:0016491

tr|T1EP86|T1EP86_HELRO
Uncharacterized protein
Search

tr|T1EP87|T1EP87_HELRO
Uncharacterized protein
Search

0.58	GO:0071805	potassium ion transmembrane transport
0.50	GO:0034765	regulation of ion transmembrane transport
0.37	GO:0042391	regulation of membrane potential
0.33	GO:0006265	DNA topological change
0.33	GO:0006468	protein phosphorylation
0.33	GO:0006508	proteolysis

0.64	GO:0005216	ion channel activity
0.59	GO:0022832	voltage-gated channel activity
0.58	GO:0015079	potassium ion transmembrane transporter activity
0.34	GO:0004692	cGMP-dependent protein kinase activity
0.33	GO:0061505	DNA topoisomerase II activity
0.33	GO:0004222	metalloendopeptidase activity
0.33	GO:0008094	DNA-dependent ATPase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0003677	DNA binding
0.32	GO:0008144	drug binding

0.36

GO:0005887

integral component of plasma membrane

0.34

EC:2.7.11.12

GO:0004692

tr|T1EP88|T1EP88_HELRO
Uncharacterized protein
Search

tr|T1EP89|T1EP89_HELRO
Uncharacterized protein
Search

tr|T1EP90|T1EP90_HELRO
Uncharacterized protein
Search

tr|T1EP91|T1EP91_HELRO
Uncharacterized protein
Search

tr|T1EP92|T1EP92_HELRO
Uncharacterized protein
Search

0.67	GO:0019441	tryptophan catabolic process to kynurenine
0.64	GO:0034354	'de novo' NAD biosynthetic process from tryptophan
0.32	GO:0006508	proteolysis

0.68	GO:0004061	arylformamidase activity
0.34	GO:0052689	carboxylic ester hydrolase activity
0.33	GO:0016298	lipase activity
0.32	GO:0017171	serine hydrolase activity
0.32	GO:0070011	peptidase activity, acting on L-amino acid peptides

0.56	GO:0005829	cytosol
0.51	GO:0005634	nucleus
0.35	GO:0016272	prefoldin complex
0.35	GO:0030672	synaptic vesicle membrane
0.35	GO:0031594	neuromuscular junction
0.30	GO:0016021	integral component of membrane

0.68	EC:3.5.1.9	GO:0004061
0.34	KEGG:R00630	GO:0052689

tr|T1EP93|T1EP93_HELRO
Uncharacterized protein
Search

0.79	GO:0010923	negative regulation of phosphatase activity
0.78	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway
0.75	GO:0000122	negative regulation of transcription by RNA polymerase II
0.73	GO:0001558	regulation of cell growth
0.72	GO:0071363	cellular response to growth factor stimulus
0.72	GO:0071383	cellular response to steroid hormone stimulus
0.71	GO:0009615	response to virus
0.47	GO:0035308	negative regulation of protein dephosphorylation
0.46	GO:0043666	regulation of phosphoprotein phosphatase activity
0.42	GO:0006457	protein folding

0.84	GO:0001106	RNA polymerase II transcription corepressor activity
0.76	GO:0051219	phosphoprotein binding
0.74	GO:0003682	chromatin binding
0.66	GO:0019212	phosphatase inhibitor activity
0.47	GO:0019888	protein phosphatase regulator activity
0.42	GO:0051082	unfolded protein binding
0.35	GO:0016301	kinase activity
0.35	GO:0042302	structural constituent of cuticle
0.35	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.34	GO:0140096	catalytic activity, acting on a protein

0.78	GO:0005665	DNA-directed RNA polymerase II, core complex
0.62	GO:0005829	cytosol
0.47	GO:0030425	dendrite
0.45	GO:0016272	prefoldin complex
0.40	GO:0005739	mitochondrion

0.35

GO:0016773

tr|T1EP94|T1EP94_HELRO
Uncharacterized protein
Search

tr|T1EP95|T1EP95_HELRO
Uncharacterized protein
Search

0.46	GO:0006470	protein dephosphorylation
0.41	GO:0007018	microtubule-based movement
0.41	GO:0032446	protein modification by small protein conjugation
0.40	GO:0080090	regulation of primary metabolic process
0.40	GO:0060255	regulation of macromolecule metabolic process
0.40	GO:0051171	regulation of nitrogen compound metabolic process
0.40	GO:0042753	positive regulation of circadian rhythm
0.39	GO:0031326	regulation of cellular biosynthetic process
0.39	GO:0018205	peptidyl-lysine modification
0.38	GO:0043547	positive regulation of GTPase activity

0.47	GO:0004721	phosphoprotein phosphatase activity
0.43	GO:0008270	zinc ion binding
0.42	GO:0003712	transcription cofactor activity
0.42	GO:0019787	ubiquitin-like protein transferase activity
0.42	GO:0003777	microtubule motor activity
0.40	GO:0004491	methylmalonate-semialdehyde dehydrogenase (acylating) activity
0.40	GO:0004674	protein serine/threonine kinase activity
0.39	GO:0032559	adenyl ribonucleotide binding
0.39	GO:0003735	structural constituent of ribosome
0.39	GO:0005096	GTPase activator activity

0.38	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.47

GO:0004721

tr|T1EP96|T1EP96_HELRO
Uncharacterized protein
Search

tr|T1EP97|T1EP97_HELRO
Uncharacterized protein
Search

tr|T1EP98|T1EP98_HELRO
Uncharacterized protein
Search

0.64

GO:0006313

transposition, DNA-mediated

0.65	GO:0004803	transposase activity
0.49	GO:0003677	DNA binding

tr|T1EP99|T1EP99_HELRO
Uncharacterized protein
Search

tr|T1EPA0|T1EPA0_HELRO
Uncharacterized protein
Search

0.51	Transmembrane protein 165

0.35	GO:0032468	Golgi calcium ion homeostasis
0.34	GO:0070588	calcium ion transmembrane transport

0.38	GO:0005509	calcium ion binding
0.34	GO:0015085	calcium ion transmembrane transporter activity

0.35	GO:0005797	Golgi medial cisterna
0.34	GO:0005801	cis-Golgi network
0.34	GO:0000324	fungal-type vacuole
0.30	GO:0044425	membrane part

tr|T1EPA1|T1EPA1_HELRO
Uncharacterized protein
Search

tr|T1EPA2|T1EPA2_HELRO
Uncharacterized protein
Search

0.34	GO:0097659	nucleic acid-templated transcription
0.34	GO:2001141	regulation of RNA biosynthetic process
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression
0.33	GO:0010467	gene expression
0.33	GO:0034645	cellular macromolecule biosynthetic process

0.80	GO:0045735	nutrient reservoir activity
0.35	GO:0046983	protein dimerization activity
0.34	GO:0003700	DNA binding transcription factor activity
0.33	GO:0003677	DNA binding

0.36	GO:0005667	transcription factor complex
0.34	GO:0005634	nucleus
0.33	GO:0005737	cytoplasm

tr|T1EPA3|T1EPA3_HELRO
Uncharacterized protein
Search

0.54

GO:0007165

signal transduction

0.30

GO:0044425

membrane part

tr|T1EPA4|T1EPA4_HELRO
Uncharacterized protein
Search

0.74	GO:0043631	RNA polyadenylation
0.64	GO:0031123	RNA 3'-end processing
0.42	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.39	GO:0007020	microtubule nucleation
0.37	GO:0006397	mRNA processing

0.72	GO:0004652	polynucleotide adenylyltransferase activity
0.52	GO:0003723	RNA binding
0.44	GO:0004527	exonuclease activity
0.43	GO:0016874	ligase activity
0.43	GO:0004519	endonuclease activity
0.39	GO:0043015	gamma-tubulin binding

0.56	GO:0005634	nucleus
0.38	GO:0000922	spindle pole
0.38	GO:0005815	microtubule organizing center
0.37	GO:0005874	microtubule
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.72

EC:2.7.7.19

GO:0004652

tr|T1EPA5|T1EPA5_HELRO
Uncharacterized protein
Search

tr|T1EPA6|T1EPA6_HELRO
Uncharacterized protein
Search

tr|T1EPA7|T1EPA7_HELRO
Uncharacterized protein
Search

tr|T1EPA8|T1EPA8_HELRO
Uncharacterized protein
Search

tr|T1EPA9|T1EPA9_HELRO
Uncharacterized protein
Search

tr|T1EPB0|T1EPB0_HELRO
Uncharacterized protein
Search

tr|T1EPB1|T1EPB1_HELRO
Uncharacterized protein
Search

tr|T1EPB2|T1EPB2_HELRO
Uncharacterized protein
Search

tr|T1EPB3|T1EPB3_HELRO
Uncharacterized protein
Search

tr|T1EPB4|T1EPB4_HELRO
Uncharacterized protein
Search

tr|T1EPB5|T1EPB5_HELRO
Uncharacterized protein
Search

0.75	Mitochondrial ribosomal protein l46

0.35	GO:0070126	mitochondrial translational termination
0.35	GO:0070125	mitochondrial translational elongation
0.34	GO:0006887	exocytosis
0.34	GO:0001172	transcription, RNA-templated
0.34	GO:0006397	mRNA processing

0.51	GO:0016787	hydrolase activity
0.40	GO:0003735	structural constituent of ribosome
0.34	GO:0003968	RNA-directed 5'-3' RNA polymerase activity

0.53	GO:0005840	ribosome
0.50	GO:0005759	mitochondrial matrix
0.47	GO:0030054	cell junction
0.46	GO:0005654	nucleoplasm
0.35	GO:0000145	exocyst
0.34	GO:0031966	mitochondrial membrane
0.34	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.51

GO:0016787

tr|T1EPB6|T1EPB6_HELRO
Uncharacterized protein
Search

tr|T1EPB7|T1EPB7_HELRO
Uncharacterized protein
Search

tr|T1EPB8|T1EPB8_HELRO
Uncharacterized protein
Search

tr|T1EPB9|T1EPB9_HELRO
Uncharacterized protein
Search

0.65	mRNA-decapping enzyme 2

0.41	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA
0.39	GO:0031087	deadenylation-independent decapping of nuclear-transcribed mRNA
0.39	GO:0034063	stress granule assembly
0.38	GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter
0.33	GO:0046656	folic acid biosynthetic process

0.70	GO:0030145	manganese ion binding
0.57	GO:0003723	RNA binding
0.51	GO:0016787	hydrolase activity
0.37	GO:0003682	chromatin binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.40	GO:0000932	P-body
0.39	GO:0098745	Dcp1-Dcp2 complex
0.37	GO:0010494	cytoplasmic stress granule
0.37	GO:0098562	cytoplasmic side of membrane
0.35	GO:0005634	nucleus

0.51

GO:0016787

tr|T1EPC0|T1EPC0_HELRO
Uncharacterized protein
Search

ECHDC1

0.87	Ethylmalonyl-CoA decarboxylase

0.39	GO:0006635	fatty acid beta-oxidation
0.35	GO:0050829	defense response to Gram-negative bacterium
0.35	GO:0001676	long-chain fatty acid metabolic process
0.34	GO:0006633	fatty acid biosynthetic process

0.43	GO:0004300	enoyl-CoA hydratase activity
0.39	GO:0016831	carboxy-lyase activity
0.37	GO:0016853	isomerase activity
0.35	GO:0004467	long-chain fatty acid-CoA ligase activity

0.41	GO:0005829	cytosol
0.36	GO:0005739	mitochondrion
0.30	GO:0044425	membrane part

0.43

EC:4.2.1.17

GO:0004300

tr|T1EPC1|T1EPC1_HELRO
Uncharacterized protein
Search

ECHDC1

0.72	Ethylmalonyl-CoA decarboxylase

0.48

GO:0006635

fatty acid beta-oxidation

0.51	GO:0004300	enoyl-CoA hydratase activity
0.43	GO:0016831	carboxy-lyase activity
0.42	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity
0.40	GO:0016853	isomerase activity
0.36	GO:0004490	methylglutaconyl-CoA hydratase activity
0.36	GO:0003860	3-hydroxyisobutyryl-CoA hydrolase activity

0.46	GO:0005829	cytosol
0.40	GO:0005739	mitochondrion

0.51	EC:4.2.1.17	GO:0004300
0.36	KEGG:R02085	GO:0004490

tr|T1EPC2|T1EPC2_HELRO
Uncharacterized protein
Search

tr|T1EPC3|T1EPC3_HELRO
Uncharacterized protein
Search

tr|T1EPC4|T1EPC4_HELRO
Uncharacterized protein
Search

0.10	ADP-ribosylation factor protein 1 (Fragment)

0.46	GO:1903292	protein localization to Golgi membrane
0.45	GO:0090158	endoplasmic reticulum membrane organization
0.45	GO:0060628	regulation of ER to Golgi vesicle-mediated transport
0.45	GO:0070861	regulation of protein exit from endoplasmic reticulum
0.45	GO:0033363	secretory granule organization
0.44	GO:0033227	dsRNA transport
0.44	GO:0007431	salivary gland development
0.44	GO:0007030	Golgi organization
0.44	GO:0035220	wing disc development
0.42	GO:0030334	regulation of cell migration

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0019904	protein domain specific binding
0.38	GO:0046872	metal ion binding
0.34	GO:0003924	GTPase activity
0.34	GO:0008047	enzyme activator activity
0.32	GO:0004462	lactoylglutathione lyase activity
0.32	GO:0003735	structural constituent of ribosome

0.45	GO:0005622	intracellular
0.40	GO:0012505	endomembrane system
0.37	GO:0044422	organelle part
0.37	GO:0043227	membrane-bounded organelle
0.34	GO:0043230	extracellular organelle
0.34	GO:0098793	presynapse
0.34	GO:0005615	extracellular space
0.32	GO:1990904	ribonucleoprotein complex
0.32	GO:0043228	non-membrane-bounded organelle
0.30	GO:0016020	membrane

0.32	EC:4.4.1.5	GO:0004462
0.32	KEGG:R02530	GO:0004462

tr|T1EPC5|T1EPC5_HELRO
Uncharacterized protein
Search

0.44	GO:0007165	signal transduction
0.39	GO:0034220	ion transmembrane transport
0.39	GO:1903506	regulation of nucleic acid-templated transcription
0.39	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.39	GO:0010468	regulation of gene expression
0.38	GO:0006468	protein phosphorylation

0.48	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.44	GO:0005230	extracellular ligand-gated ion channel activity
0.43	GO:0030246	carbohydrate binding
0.42	GO:0004888	transmembrane signaling receptor activity
0.39	GO:0004672	protein kinase activity
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding

0.41	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|T1EPC6|T1EPC6_HELRO
Uncharacterized protein
Search

0.43	GO:0043087	regulation of GTPase activity
0.41	GO:0051345	positive regulation of hydrolase activity
0.41	GO:0042254	ribosome biogenesis
0.41	GO:0044719	regulation of imaginal disc-derived wing size
0.40	GO:0008039	synaptic target recognition
0.40	GO:0016203	muscle attachment
0.40	GO:0016319	mushroom body development
0.40	GO:0050789	regulation of biological process
0.40	GO:0051716	cellular response to stimulus
0.40	GO:0007298	border follicle cell migration

0.42	GO:0005096	GTPase activator activity
0.41	GO:0003676	nucleic acid binding
0.39	GO:0031386	protein tag
0.39	GO:0016849	phosphorus-oxygen lyase activity
0.38	GO:0004674	protein serine/threonine kinase activity
0.38	GO:0008270	zinc ion binding
0.38	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.38	GO:0003712	transcription cofactor activity
0.37	GO:0008146	sulfotransferase activity
0.37	GO:0000166	nucleotide binding

0.46	GO:0005634	nucleus
0.38	GO:1902493	acetyltransferase complex
0.37	GO:1905368	peptidase complex
0.36	GO:0043233	organelle lumen
0.35	GO:0043234	protein complex
0.35	GO:0044446	intracellular organelle part
0.34	GO:0005886	plasma membrane
0.33	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.39

EC:4.6

GO:0016849

tr|T1EPC7|T1EPC7_HELRO
Uncharacterized protein
Search

0.43

GO:0046872

metal ion binding

0.30

GO:0044425

membrane part

tr|T1EPC8|T1EPC8_HELRO
Uncharacterized protein
Search

0.44	GO:0060255	regulation of macromolecule metabolic process
0.44	GO:0031323	regulation of cellular metabolic process
0.44	GO:0051171	regulation of nitrogen compound metabolic process
0.44	GO:0080090	regulation of primary metabolic process
0.44	GO:0009889	regulation of biosynthetic process
0.41	GO:0016042	lipid catabolic process
0.40	GO:0036211	protein modification process
0.39	GO:0065009	regulation of molecular function
0.39	GO:0044267	cellular protein metabolic process
0.37	GO:0016310	phosphorylation

0.45	GO:0003700	DNA binding transcription factor activity
0.40	GO:0008270	zinc ion binding
0.39	GO:0140096	catalytic activity, acting on a protein
0.39	GO:0003676	nucleic acid binding
0.38	GO:0016787	hydrolase activity
0.38	GO:0005515	protein binding
0.38	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.38	GO:0098772	molecular function regulator
0.38	GO:0016301	kinase activity
0.38	GO:0097367	carbohydrate derivative binding

0.39	GO:0005634	nucleus
0.36	GO:0005667	transcription factor complex
0.36	GO:0008352	katanin complex
0.36	GO:0020011	apicoplast
0.35	GO:0005829	cytosol
0.35	GO:0000131	incipient cellular bud site
0.35	GO:0043332	mating projection tip
0.34	GO:0005874	microtubule
0.34	GO:0005657	replication fork
0.34	GO:0010008	endosome membrane

0.38

GO:0016787

tr|T1EPC9|T1EPC9_HELRO
Uncharacterized protein
Search

tr|T1EPD0|T1EPD0_HELRO
Uncharacterized protein
Search

tr|T1EPD1|T1EPD1_HELRO
Uncharacterized protein
Search

0.45	GO:0010628	positive regulation of gene expression
0.44	GO:1903508	positive regulation of nucleic acid-templated transcription
0.43	GO:0051568	histone H3-K4 methylation
0.42	GO:0060446	branching involved in open tracheal system development
0.42	GO:0006357	regulation of transcription by RNA polymerase II
0.42	GO:0043524	negative regulation of neuron apoptotic process
0.42	GO:0016348	imaginal disc-derived leg joint morphogenesis
0.41	GO:0035146	tube fusion
0.41	GO:0007427	epithelial cell migration, open tracheal system
0.41	GO:0060571	morphogenesis of an epithelial fold

0.46	GO:0030246	carbohydrate binding
0.46	GO:0003677	DNA binding
0.43	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.43	GO:0046983	protein dimerization activity
0.42	GO:0051219	phosphoprotein binding
0.41	GO:0003682	chromatin binding
0.41	GO:0001067	regulatory region nucleic acid binding
0.40	GO:0042802	identical protein binding
0.40	GO:0140110	transcription regulator activity
0.38	GO:0046872	metal ion binding

0.51	GO:0005634	nucleus
0.42	GO:0070013	intracellular organelle lumen
0.42	GO:0034708	methyltransferase complex
0.39	GO:0044446	intracellular organelle part
0.39	GO:0005694	chromosome
0.37	GO:0043234	protein complex
0.35	GO:0019028	viral capsid
0.35	GO:0032040	small-subunit processome
0.35	GO:1904949	ATPase complex
0.35	GO:0044815	DNA packaging complex

0.36

EC:2.8.2.20

GO:0008476

tr|T1EPD2|T1EPD2_HELRO
Uncharacterized protein
Search

tr|T1EPD3|T1EPD3_HELRO
Uncharacterized protein
Search

tr|T1EPD4|T1EPD4_HELRO
Uncharacterized protein
Search

tr|T1EPD5|T1EPD5_HELRO
Uncharacterized protein
Search

tr|T1EPD6|T1EPD6_HELRO
Uncharacterized protein
Search

0.65	GO:0030968	endoplasmic reticulum unfolded protein response
0.60	GO:0045944	positive regulation of transcription by RNA polymerase II
0.53	GO:0002062	chondrocyte differentiation
0.49	GO:0006888	ER to Golgi vesicle-mediated transport
0.48	GO:0006366	transcription by RNA polymerase II
0.35	GO:0003330	regulation of extracellular matrix constituent secretion
0.35	GO:0060628	regulation of ER to Golgi vesicle-mediated transport
0.34	GO:0070647	protein modification by small protein conjugation or removal
0.34	GO:0006886	intracellular protein transport
0.34	GO:0042147	retrograde transport, endosome to Golgi

0.67	GO:0035497	cAMP response element binding
0.59	GO:0003700	DNA binding transcription factor activity
0.34	GO:0017112	Rab guanyl-nucleotide exchange factor activity
0.33	GO:0031386	protein tag
0.33	GO:0003729	mRNA binding
0.33	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.33	GO:0004497	monooxygenase activity
0.33	GO:0004842	ubiquitin-protein transferase activity
0.32	GO:0005524	ATP binding
0.32	GO:0008270	zinc ion binding

0.47	GO:0005783	endoplasmic reticulum
0.46	GO:0005654	nucleoplasm
0.38	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.38	GO:0031984	organelle subcompartment
0.35	GO:0044431	Golgi apparatus part
0.34	GO:0098588	bounding membrane of organelle
0.34	GO:0005829	cytosol
0.34	GO:0032045	guanyl-nucleotide exchange factor complex
0.33	GO:0000445	THO complex part of transcription export complex
0.33	GO:0048786	presynaptic active zone

0.33	EC:3.4.19.12	GO:0036459
0.33	KEGG:R03876	GO:0004842

tr|T1EPD7|T1EPD7_HELRO
Uncharacterized protein
Search

0.10	Transcription initiation factor TFIID subunit 12

0.54	GO:0006352	DNA-templated transcription, initiation
0.43	GO:0006413	translational initiation
0.43	GO:0016310	phosphorylation
0.40	GO:0036211	protein modification process
0.39	GO:0060275	maintenance of stationary phase in response to starvation
0.39	GO:0016569	covalent chromatin modification
0.39	GO:0016226	iron-sulfur cluster assembly
0.39	GO:0006357	regulation of transcription by RNA polymerase II
0.39	GO:0051173	positive regulation of nitrogen compound metabolic process
0.39	GO:0010604	positive regulation of macromolecule metabolic process

0.57	GO:0046982	protein heterodimerization activity
0.52	GO:0000829	inositol heptakisphosphate kinase activity
0.43	GO:0008270	zinc ion binding
0.43	GO:0003743	translation initiation factor activity
0.39	GO:0008199	ferric iron binding
0.39	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.38	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.38	GO:0051864	histone demethylase activity (H3-K36 specific)
0.38	GO:0004402	histone acetyltransferase activity
0.37	GO:0004672	protein kinase activity

0.62	GO:0046695	SLIK (SAGA-like) complex
0.61	GO:0005669	transcription factor TFIID complex
0.61	GO:0000124	SAGA complex
0.38	GO:1902562	H4 histone acetyltransferase complex
0.37	GO:0005829	cytosol
0.36	GO:0005680	anaphase-promoting complex
0.36	GO:0031252	cell leading edge
0.35	GO:0005938	cell cortex
0.35	GO:0000785	chromatin
0.35	GO:0034399	nuclear periphery

0.38	EC:1.14.11.27	GO:0051864
0.34	KEGG:R03876	GO:0004842

tr|T1EPD8|T1EPD8_HELRO
Uncharacterized protein
Search

0.45	GO:0007165	signal transduction
0.39	GO:0006468	protein phosphorylation
0.39	GO:0034220	ion transmembrane transport

0.44	GO:0005230	extracellular ligand-gated ion channel activity
0.43	GO:0030246	carbohydrate binding
0.42	GO:0004888	transmembrane signaling receptor activity
0.40	GO:0004672	protein kinase activity
0.38	GO:0046872	metal ion binding
0.37	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0016020

membrane

tr|T1EPD9|T1EPD9_HELRO
Uncharacterized protein
Search

tr|T1EPE0|T1EPE0_HELRO
Uncharacterized protein
Search

tr|T1EPE1|T1EPE1_HELRO
Uncharacterized protein
Search

tr|T1EPE2|T1EPE2_HELRO
Uncharacterized protein
Search

tr|T1EPE3|T1EPE3_HELRO
Uncharacterized protein
Search

0.69	GO:0006024	glycosaminoglycan biosynthetic process
0.53	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process
0.53	GO:0015012	heparan sulfate proteoglycan biosynthetic process
0.53	GO:0030202	heparin metabolic process
0.45	GO:0044272	sulfur compound biosynthetic process
0.43	GO:0030204	chondroitin sulfate metabolic process
0.36	GO:0034605	cellular response to heat
0.35	GO:0048681	negative regulation of axon regeneration
0.34	GO:0070555	response to interleukin-1
0.34	GO:0048701	embryonic cranial skeleton morphogenesis

0.86	GO:0030158	protein xylosyltransferase activity
0.77	GO:0008375	acetylglucosaminyltransferase activity

0.41	GO:0000139	Golgi membrane
0.40	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

0.86

EC:2.4.2.26

GO:0030158

tr|T1EPE4|T1EPE4_HELRO
Uncharacterized protein
Search

tr|T1EPE5|T1EPE5_HELRO
Uncharacterized protein
Search

0.63	GO:0035556	intracellular signal transduction
0.61	GO:0007186	G-protein coupled receptor signaling pathway
0.61	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.37	GO:0050790	regulation of catalytic activity

0.56	GO:0004871	signal transducer activity
0.40	GO:0005092	GDP-dissociation inhibitor activity

0.69	GO:1905360	GTPase complex
0.68	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.57	GO:0098797	plasma membrane protein complex
0.30	GO:0031224	intrinsic component of membrane

tr|T1EPE6|T1EPE6_HELRO
Uncharacterized protein
Search

tr|T1EPE7|T1EPE7_HELRO
Uncharacterized protein
Search

0.82	Nonmuscle myosin essential light chain

0.34	GO:0009612	response to mechanical stimulus
0.34	GO:0055085	transmembrane transport
0.34	GO:0005513	detection of calcium ion
0.32	GO:0007165	signal transduction
0.32	GO:0055114	oxidation-reduction process

0.70	GO:0005509	calcium ion binding
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.33	GO:0005515	protein binding
0.32	GO:0004871	signal transducer activity
0.32	GO:0016758	transferase activity, transferring hexosyl groups

0.36	GO:0005634	nucleus
0.33	GO:0005829	cytosol
0.33	GO:0016459	myosin complex
0.33	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

0.34

GO:0032440

tr|T1EPE8|T1EPE8_HELRO
Uncharacterized protein
Search

tr|T1EPE9|T1EPE9_HELRO
Uncharacterized protein
Search

0.52	GO:1903506	regulation of nucleic acid-templated transcription
0.52	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.52	GO:0010468	regulation of gene expression
0.39	GO:0016567	protein ubiquitination
0.37	GO:0007416	synapse assembly
0.37	GO:0023051	regulation of signaling
0.37	GO:0033036	macromolecule localization
0.37	GO:0030968	endoplasmic reticulum unfolded protein response
0.37	GO:0097035	regulation of membrane lipid distribution
0.37	GO:0071702	organic substance transport

0.56	GO:0003700	DNA binding transcription factor activity
0.39	GO:0004842	ubiquitin-protein transferase activity
0.38	GO:0003723	RNA binding
0.37	GO:0035497	cAMP response element binding
0.37	GO:0098772	molecular function regulator
0.37	GO:0004012	phospholipid-translocating ATPase activity
0.36	GO:0031176	endo-1,4-beta-xylanase activity
0.36	GO:0046872	metal ion binding
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0016301	kinase activity

0.37	GO:0048786	presynaptic active zone
0.37	GO:0034066	RIC1-RGP1 guanyl-nucleotide exchange factor complex
0.36	GO:0031984	organelle subcompartment
0.36	GO:0005634	nucleus
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0044432	endoplasmic reticulum part
0.35	GO:0098588	bounding membrane of organelle
0.35	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.37	EC:3.6.3.1	GO:0004012
0.39	KEGG:R03876	GO:0004842

tr|T1EPF0|T1EPF0_HELRO
Uncharacterized protein
Search

0.48	GO:0006937	regulation of muscle contraction
0.46	GO:0032501	multicellular organismal process
0.43	GO:0120036	plasma membrane bounded cell projection organization
0.43	GO:0048468	cell development
0.40	GO:0006360	transcription by RNA polymerase I
0.40	GO:0006457	protein folding
0.39	GO:1904750	negative regulation of protein localization to nucleolus
0.38	GO:0006356	regulation of transcription by RNA polymerase I
0.38	GO:0007076	mitotic chromosome condensation
0.38	GO:0036211	protein modification process

0.47	GO:0017022	myosin binding
0.45	GO:0005516	calmodulin binding
0.43	GO:0003779	actin binding
0.41	GO:0005509	calcium ion binding
0.40	GO:0051082	unfolded protein binding
0.40	GO:0008270	zinc ion binding
0.39	GO:0005198	structural molecule activity
0.39	GO:0001168	transcription factor activity, RNA polymerase I upstream control element sequence-specific binding
0.39	GO:0003682	chromatin binding
0.39	GO:0003677	DNA binding

0.49	GO:0099512	supramolecular fiber
0.48	GO:0044430	cytoskeletal part
0.45	GO:0015629	actin cytoskeleton
0.44	GO:0045111	intermediate filament cytoskeleton
0.42	GO:0044444	cytoplasmic part
0.41	GO:0005634	nucleus
0.41	GO:0043234	protein complex
0.40	GO:0044427	chromosomal part
0.39	GO:0000793	condensed chromosome
0.37	GO:0070013	intracellular organelle lumen

0.38	EC:2.7.7.6	GO:0003899
0.37	KEGG:R03877	GO:0016851

tr|T1EPF1|T1EPF1_HELRO
Uncharacterized protein
Search

0.53	GO:0006413	translational initiation
0.41	GO:0099120	socially cooperative development
0.40	GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity
0.39	GO:0009736	cytokinin-activated signaling pathway
0.39	GO:0043412	macromolecule modification
0.38	GO:0032259	methylation
0.38	GO:0019933	cAMP-mediated signaling
0.38	GO:0007275	multicellular organism development
0.38	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
0.37	GO:0031000	response to caffeine

0.54	GO:0003743	translation initiation factor activity
0.40	GO:0009784	transmembrane receptor histidine kinase activity
0.38	GO:0008168	methyltransferase activity
0.37	GO:0004535	poly(A)-specific ribonuclease activity
0.37	GO:0003729	mRNA binding
0.37	GO:0043022	ribosome binding
0.37	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.37	GO:0046872	metal ion binding
0.37	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity
0.36	GO:0003777	microtubule motor activity

0.40	GO:0020011	apicoplast
0.38	GO:0009897	external side of plasma membrane
0.38	GO:0044456	synapse part
0.38	GO:0022627	cytosolic small ribosomal subunit
0.37	GO:0005634	nucleus
0.37	GO:0030015	CCR4-NOT core complex
0.37	GO:0009898	cytoplasmic side of plasma membrane
0.37	GO:0000932	P-body
0.36	GO:0097458	neuron part
0.36	GO:0005887	integral component of plasma membrane

0.38

GO:0008168

tr|T1EPF2|T1EPF2_HELRO
Uncharacterized protein
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0.48	GO:0006035	cuticle chitin biosynthetic process
0.47	GO:0035158	regulation of tube diameter, open tracheal system
0.46	GO:0008362	chitin-based embryonic cuticle biosynthetic process
0.46	GO:0048085	adult chitin-containing cuticle pigmentation
0.46	GO:0060439	trachea morphogenesis
0.46	GO:0007443	Malpighian tubule morphogenesis
0.44	GO:0001838	embryonic epithelial tube formation
0.43	GO:0009611	response to wounding
0.40	GO:0006038	cell wall chitin biosynthetic process
0.35	GO:0035002	liquid clearance, open tracheal system

0.69	GO:0016758	transferase activity, transferring hexosyl groups
0.41	GO:0008194	UDP-glycosyltransferase activity
0.35	GO:0003779	actin binding
0.35	GO:0003774	motor activity
0.35	GO:0008017	microtubule binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.43	GO:0045177	apical part of cell
0.40	GO:0030428	cell septum
0.36	GO:0016459	myosin complex
0.35	GO:0005737	cytoplasm
0.35	GO:0071944	cell periphery
0.30	GO:0016020	membrane

0.69

EC:2.4.1

GO:0016758

tr|T1EPF3|T1EPF3_HELRO
Uncharacterized protein
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tr|T1EPF4|T1EPF4_HELRO
Uncharacterized protein
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tr|T1EPF5|T1EPF5_HELRO
Uncharacterized protein
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0.30	8-oxo-dGDP phosphatase NUDT18

0.51

GO:0016787

hydrolase activity

0.51