Queries 23001 to 23328

GO:0008233

tr|T1G8Y7|T1G8Y7_HELRO
Uncharacterized protein
Search

tr|T1G8Y8|T1G8Y8_HELRO
Uncharacterized protein
Search

0.70	Potassium voltage-gated channel protein Shab

0.75	GO:0034765	regulation of ion transmembrane transport
0.74	GO:0051260	protein homooligomerization
0.73	GO:0071805	potassium ion transmembrane transport
0.51	GO:1900454	positive regulation of long term synaptic depression
0.50	GO:0090314	positive regulation of protein targeting to membrane
0.49	GO:0046676	negative regulation of insulin secretion
0.49	GO:0098900	regulation of action potential
0.49	GO:0001508	action potential
0.49	GO:0071333	cellular response to glucose stimulus
0.41	GO:0072659	protein localization to plasma membrane

0.78	GO:0005249	voltage-gated potassium channel activity
0.48	GO:0044325	ion channel binding
0.39	GO:0046982	protein heterodimerization activity
0.34	GO:0047485	protein N-terminus binding
0.34	GO:0042162	telomeric DNA binding
0.34	GO:0000149	SNARE binding
0.34	GO:0042803	protein homodimerization activity

0.78	GO:0008076	voltage-gated potassium channel complex
0.51	GO:0032809	neuronal cell body membrane
0.48	GO:0030425	dendrite
0.42	GO:0043204	perikaryon
0.39	GO:0016328	lateral plasma membrane
0.39	GO:0042383	sarcolemma
0.38	GO:0030424	axon
0.38	GO:0045211	postsynaptic membrane
0.37	GO:0030054	cell junction
0.35	GO:0044214	spanning component of plasma membrane

tr|T1G8Y9|T1G8Y9_HELRO
Uncharacterized protein
Search

0.10	arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1

0.76	GO:0043547	positive regulation of GTPase activity
0.34	GO:1905279	regulation of retrograde transport, endosome to Golgi
0.33	GO:0007219	Notch signaling pathway
0.33	GO:0006886	intracellular protein transport
0.32	GO:0030154	cell differentiation
0.32	GO:0007275	multicellular organism development
0.32	GO:0006468	protein phosphorylation

0.76	GO:0005096	GTPase activator activity
0.52	GO:0046872	metal ion binding
0.32	GO:0003677	DNA binding
0.32	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.33	GO:0030428	cell septum
0.33	GO:0051286	cell tip
0.33	GO:0032153	cell division site
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

tr|T1G8Z0|T1G8Z0_HELRO
Uncharacterized protein
Search

FBXL20

0.85	F-box and leucine-rich repeat protein 2

0.75	GO:0001662	behavioral fear response
0.60	GO:0034976	response to endoplasmic reticulum stress
0.48	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
0.47	GO:0016567	protein ubiquitination
0.43	GO:0035882	defecation rhythm
0.42	GO:0043053	dauer entry
0.38	GO:0043687	post-translational protein modification
0.35	GO:0035556	intracellular signal transduction

0.47	GO:0004842	ubiquitin-protein transferase activity
0.37	GO:0005515	protein binding

0.48	GO:0019005	SCF ubiquitin ligase complex
0.36	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.47

KEGG:R03876

GO:0004842

tr|T1G8Z1|T1G8Z1_HELRO
Uncharacterized protein
Search

TTC38

0.63	Tetratricopeptide repeat protein 38

0.30

GO:0044425

membrane part

tr|T1G8Z2|T1G8Z2_HELRO
Uncharacterized protein
Search

PAK4

0.39	Serine/threonine-protein kinase PAK mbt (Fragment)

0.63	GO:0006468	protein phosphorylation
0.46	GO:0045315	positive regulation of compound eye photoreceptor development
0.45	GO:2000047	regulation of cell-cell adhesion mediated by cadherin
0.45	GO:0048513	animal organ development
0.44	GO:0045792	negative regulation of cell size
0.44	GO:0009653	anatomical structure morphogenesis
0.43	GO:0046530	photoreceptor cell differentiation
0.43	GO:0007030	Golgi organization
0.42	GO:0018209	peptidyl-serine modification
0.42	GO:0060322	head development

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0017048	Rho GTPase binding
0.35	GO:0098641	cadherin binding involved in cell-cell adhesion
0.34	GO:0005057	signal transducer activity, downstream of receptor
0.33	GO:0003676	nucleic acid binding
0.33	GO:0008270	zinc ion binding
0.33	GO:0003700	DNA binding transcription factor activity

0.43	GO:0005913	cell-cell adherens junction
0.36	GO:0005886	plasma membrane
0.36	GO:0005737	cytoplasm
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

tr|T1G8Z3|T1G8Z3_HELRO
Uncharacterized protein
Search

DPAGT1

0.79	UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase

0.83	GO:0006488	dolichol-linked oligosaccharide biosynthetic process
0.80	GO:0006487	protein N-linked glycosylation
0.48	GO:0046465	dolichyl diphosphate metabolic process
0.41	GO:0008654	phospholipid biosynthetic process
0.41	GO:0006040	amino sugar metabolic process
0.38	GO:0006022	aminoglycan metabolic process
0.38	GO:0019348	dolichol metabolic process
0.37	GO:0005975	carbohydrate metabolic process
0.37	GO:0017144	drug metabolic process
0.35	GO:0016094	polyprenol biosynthetic process

0.85	GO:0003975	UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity
0.77	GO:0008963	phospho-N-acetylmuramoyl-pentapeptide-transferase activity
0.53	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity
0.41	GO:0008061	chitin binding
0.39	GO:0051992	UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity
0.39	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.35	GO:0016757	transferase activity, transferring glycosyl groups

0.43	GO:0005789	endoplasmic reticulum membrane
0.38	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.85

EC:2.7.8.15

GO:0003975

tr|T1G8Z4|T1G8Z4_HELRO
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
Search

SDHA

0.67	Succinate dehydrogenase [ubiquinone] flavoprotein subunit B, mitochondrial

0.70	GO:0006099	tricarboxylic acid cycle
0.60	GO:0022900	electron transport chain
0.43	GO:0006105	succinate metabolic process
0.42	GO:0009061	anaerobic respiration
0.39	GO:0006119	oxidative phosphorylation
0.38	GO:0007399	nervous system development
0.36	GO:0006106	fumarate metabolic process
0.34	GO:0007034	vacuolar transport

0.78	GO:0008177	succinate dehydrogenase (ubiquinone) activity
0.66	GO:0050660	flavin adenine dinucleotide binding
0.38	GO:0009055	electron transfer activity
0.36	GO:0004333	fumarate hydratase activity
0.34	GO:0051087	chaperone binding

0.58	GO:0031966	mitochondrial membrane
0.58	GO:0019866	organelle inner membrane
0.47	GO:0045282	plasma membrane succinate dehydrogenase complex
0.46	GO:0045257	succinate dehydrogenase complex (ubiquinone)
0.46	GO:0045283	fumarate reductase complex
0.42	GO:0098798	mitochondrial protein complex
0.39	GO:0005730	nucleolus
0.38	GO:0043209	myelin sheath
0.36	GO:0045239	tricarboxylic acid cycle enzyme complex
0.30	GO:0031224	intrinsic component of membrane

0.78	EC:1.3.5.1	GO:0008177
0.78	KEGG:R02164	GO:0008177

tr|T1G8Z5|T1G8Z5_HELRO
Uncharacterized protein
Search

ABCB8

0.37	Mitochondrial ATP-binding cassette sub-family B member 8

0.55	GO:0055085	transmembrane transport
0.45	GO:0006857	oligopeptide transport
0.44	GO:0006839	mitochondrial transport
0.40	GO:0070301	cellular response to hydrogen peroxide
0.38	GO:0016246	RNA interference
0.35	GO:0042908	xenobiotic transport
0.34	GO:0015893	drug transport
0.32	GO:0022900	electron transport chain

0.66	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0035673	oligopeptide transmembrane transporter activity
0.35	GO:0042910	xenobiotic transmembrane transporter activity
0.35	GO:0015238	drug transmembrane transporter activity
0.33	GO:0020037	heme binding
0.33	GO:0009055	electron transfer activity
0.32	GO:0046872	metal ion binding

0.46	GO:0005730	nucleolus
0.43	GO:0005739	mitochondrion
0.39	GO:0005774	vacuolar membrane
0.38	GO:0097038	perinuclear endoplasmic reticulum
0.38	GO:0019866	organelle inner membrane
0.33	GO:0043190	ATP-binding cassette (ABC) transporter complex

tr|T1G8Z6|T1G8Z6_HELRO
Uncharacterized protein
Search

0.30

GO:0044425

membrane part

tr|T1G8Z7|T1G8Z7_HELRO
Uncharacterized protein
Search

0.50	GO:1903506	regulation of nucleic acid-templated transcription
0.50	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.50	GO:0010468	regulation of gene expression
0.44	GO:0045773	positive regulation of axon extension
0.43	GO:0007411	axon guidance
0.35	GO:0061321	garland nephrocyte differentiation
0.35	GO:0007516	hemocyte development
0.35	GO:0007280	pole cell migration
0.34	GO:1902679	negative regulation of RNA biosynthetic process
0.34	GO:0048542	lymph gland development

0.56	GO:0043565	sequence-specific DNA binding
0.34	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.34	GO:0001012	RNA polymerase II regulatory region DNA binding
0.34	GO:0046872	metal ion binding
0.33	GO:0003690	double-stranded DNA binding

0.59	GO:0005634	nucleus
0.33	GO:0005694	chromosome
0.33	GO:0043233	organelle lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

tr|T1G8Z8|T1G8Z8_HELRO
Uncharacterized protein
Search

0.43	Conserved oligomeric Golgi complex subunit 8

0.70	GO:0006891	intra-Golgi vesicle-mediated transport
0.56	GO:0015031	protein transport
0.33	GO:0006888	ER to Golgi vesicle-mediated transport
0.32	GO:0032259	methylation

0.32	GO:0008168	methyltransferase activity
0.32	GO:0005515	protein binding

0.81	GO:0017119	Golgi transport complex
0.62	GO:0000139	Golgi membrane
0.33	GO:0005802	trans-Golgi network

0.32

GO:0008168

tr|T1G8Z9|T1G8Z9_HELRO
Uncharacterized protein
Search

DGCR14

0.90	DiGeorge syndrome critical region gene 14

0.39

GO:0003677

DNA binding

0.68	GO:0071013	catalytic step 2 spliceosome
0.30	GO:0031224	intrinsic component of membrane

tr|T1G900|T1G900_HELRO
Uncharacterized protein
Search

0.32	RAC serine/threonine-protein kinase

0.63	GO:0006468	protein phosphorylation
0.47	GO:0035556	intracellular signal transduction
0.43	GO:0061204	paramyosin filament assembly or disassembly
0.42	GO:0071688	striated muscle myosin thick filament assembly
0.37	GO:0009272	fungal-type cell wall biogenesis
0.36	GO:0061013	regulation of mRNA catabolic process
0.36	GO:0042981	regulation of apoptotic process
0.36	GO:0048522	positive regulation of cellular process
0.36	GO:0048523	negative regulation of cellular process
0.36	GO:0018209	peptidyl-serine modification

0.64	GO:0004672	protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.46	GO:0000287	magnesium ion binding
0.42	GO:0008307	structural constituent of muscle
0.35	GO:0005245	voltage-gated calcium channel activity
0.35	GO:0030291	protein serine/threonine kinase inhibitor activity
0.35	GO:0003774	motor activity

0.41	GO:0031430	M band
0.38	GO:0005634	nucleus
0.36	GO:0005856	cytoskeleton
0.35	GO:0005891	voltage-gated calcium channel complex
0.35	GO:0070013	intracellular organelle lumen
0.35	GO:0044446	intracellular organelle part
0.34	GO:0030427	site of polarized growth
0.33	GO:0005694	chromosome
0.33	GO:0043234	protein complex
0.32	GO:0005938	cell cortex

0.33	EC:1.6.5.3	GO:0008137
0.32	KEGG:R03876	GO:0004842

tr|T1G901|T1G901_HELRO
Uncharacterized protein
Search

0.44	Fidgetin-like protein 1

0.47	GO:0010569	regulation of double-strand break repair via homologous recombination
0.44	GO:0033687	osteoblast proliferation
0.43	GO:0071479	cellular response to ionizing radiation
0.42	GO:0001649	osteoblast differentiation
0.42	GO:0007140	male meiotic nuclear division
0.42	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway
0.40	GO:0051726	regulation of cell cycle
0.38	GO:0046034	ATP metabolic process
0.35	GO:0051013	microtubule severing

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0016887	ATPase activity
0.39	GO:0000287	magnesium ion binding
0.34	GO:0005515	protein binding
0.33	GO:0140096	catalytic activity, acting on a protein

0.43	GO:0048471	perinuclear region of cytoplasm
0.42	GO:0000228	nuclear chromosome
0.38	GO:0070062	extracellular exosome

0.39

GO:0016887

tr|T1G902|T1G902_HELRO
Phosphoglycerate kinase
Search

0.47	Phosphoglycerate kinase

0.71	GO:0006757	ATP generation from ADP
0.69	GO:0006090	pyruvate metabolic process
0.68	GO:0016052	carbohydrate catabolic process
0.67	GO:0019362	pyridine nucleotide metabolic process
0.45	GO:0007525	somatic muscle development
0.45	GO:0046716	muscle cell cellular homeostasis
0.45	GO:0007520	myoblast fusion
0.42	GO:0007268	chemical synaptic transmission
0.38	GO:0019319	hexose biosynthetic process
0.38	GO:0006006	glucose metabolic process

0.79	GO:0004618	phosphoglycerate kinase activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0047134	protein-disulfide reductase activity

0.45	GO:0031430	M band
0.44	GO:0030018	Z disc
0.36	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.79	EC:2.7.2.3	GO:0004618
0.79	KEGG:R01512	GO:0004618

tr|T1G903|T1G903_HELRO
Uncharacterized protein
Search

0.63	Chaperonin containing t-complex polypeptide 1 beta subunit

0.69	GO:0006457	protein folding
0.35	GO:0090670	RNA localization to Cajal body
0.35	GO:1904869	regulation of protein localization to Cajal body
0.35	GO:1904851	positive regulation of establishment of protein localization to telomere
0.35	GO:1904874	positive regulation of telomerase RNA localization to Cajal body
0.35	GO:0051973	positive regulation of telomerase activity
0.35	GO:0007339	binding of sperm to zona pellucida
0.35	GO:0032212	positive regulation of telomere maintenance via telomerase
0.34	GO:1900182	positive regulation of protein localization to nucleus
0.34	GO:0051131	chaperone-mediated protein complex assembly

0.71	GO:0051082	unfolded protein binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0044183	protein binding involved in protein folding
0.34	GO:0031625	ubiquitin protein ligase binding

0.47	GO:0005737	cytoplasm
0.45	GO:0101031	chaperone complex
0.35	GO:0002199	zona pellucida receptor complex
0.34	GO:0043209	myelin sheath
0.34	GO:0044297	cell body
0.34	GO:0005874	microtubule
0.30	GO:0016020	membrane

tr|T1G904|T1G904_HELRO
Uncharacterized protein
Search

0.74	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.45	GO:0007399	nervous system development
0.45	GO:0048513	animal organ development
0.43	GO:0007605	sensory perception of sound
0.43	GO:0007626	locomotory behavior
0.42	GO:0120036	plasma membrane bounded cell projection organization
0.41	GO:0048468	cell development
0.41	GO:0001756	somitogenesis
0.41	GO:0007498	mesoderm development
0.40	GO:0060322	head development

0.66	GO:0005509	calcium ion binding
0.43	GO:0000829	inositol heptakisphosphate kinase activity
0.37	GO:0003700	DNA binding transcription factor activity
0.35	GO:0004930	G-protein coupled receptor activity
0.34	GO:0033857	diphosphoinositol-pentakisphosphate kinase activity
0.34	GO:0000828	inositol hexakisphosphate kinase activity
0.33	GO:0003993	acid phosphatase activity
0.33	GO:0018024	histone-lysine N-methyltransferase activity
0.33	GO:0046982	protein heterodimerization activity
0.33	GO:0004022	alcohol dehydrogenase (NAD) activity

0.53	GO:0005886	plasma membrane
0.44	GO:0032420	stereocilium
0.33	GO:0020011	apicoplast
0.32	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:2.7.4.24

GO:0033857

tr|T1G905|T1G905_HELRO
DNA helicase
Search

MCM3

0.46	Maternal DNA replication licensing factor mcm3

0.75	GO:0006270	DNA replication initiation
0.52	GO:0007049	cell cycle
0.46	GO:0030174	regulation of DNA-dependent DNA replication initiation
0.40	GO:0006268	DNA unwinding involved in DNA replication

0.55	GO:0032559	adenyl ribonucleotide binding
0.55	GO:0003677	DNA binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0004386	helicase activity
0.48	GO:0003682	chromatin binding
0.40	GO:0005515	protein binding
0.37	GO:0016887	ATPase activity

0.80	GO:0042555	MCM complex
0.50	GO:0005634	nucleus
0.48	GO:0005813	centrosome
0.45	GO:0048471	perinuclear region of cytoplasm
0.44	GO:0031974	membrane-enclosed lumen
0.42	GO:0044427	chromosomal part
0.40	GO:0000428	DNA-directed RNA polymerase complex
0.39	GO:0032993	protein-DNA complex
0.30	GO:0016020	membrane

0.37

GO:0016887

tr|T1G906|T1G906_HELRO
Uncharacterized protein
Search

LSM14A

0.80	LSM14A, mRNA processing body assembly factor

0.80	GO:0033962	cytoplasmic mRNA processing body assembly
0.79	GO:0039529	RIG-I signaling pathway
0.77	GO:0060340	positive regulation of type I interferon-mediated signaling pathway

0.68	GO:0003727	single-stranded RNA binding
0.66	GO:0003725	double-stranded RNA binding
0.62	GO:0003690	double-stranded DNA binding

0.74	GO:0000932	P-body
0.74	GO:0010494	cytoplasmic stress granule
0.62	GO:0005829	cytosol

tr|T1G907|T1G907_HELRO
Uncharacterized protein
Search

0.24	Lipid A export ATP-binding/permease protein MsbA

0.54	GO:0055085	transmembrane transport
0.39	GO:0042886	amide transport
0.38	GO:0071702	organic substance transport
0.36	GO:0042908	xenobiotic transport
0.35	GO:0015893	drug transport
0.34	GO:0010876	lipid localization
0.32	GO:0006508	proteolysis

0.65	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:1904680	peptide transmembrane transporter activity
0.36	GO:0042910	xenobiotic transmembrane transporter activity
0.35	GO:0015238	drug transmembrane transporter activity
0.34	GO:0005319	lipid transporter activity
0.34	GO:0042803	protein homodimerization activity
0.32	GO:0008233	peptidase activity

0.41	GO:0005765	lysosomal membrane
0.41	GO:0009941	chloroplast envelope
0.34	GO:0030176	integral component of endoplasmic reticulum membrane
0.34	GO:0042170	plastid membrane
0.33	GO:0005730	nucleolus
0.32	GO:0005739	mitochondrion
0.32	GO:0005886	plasma membrane

0.32

GO:0008233

tr|T1G908|T1G908_HELRO
Uncharacterized protein
Search

tr|T1G909|T1G909_HELRO
Uncharacterized protein
Search

MTHFSD

0.95	Methenyltetrahydrofolate synthetase domain containing

0.50

GO:0008298

intracellular mRNA localization

0.57	GO:0003723	RNA binding
0.35	GO:0016874	ligase activity

0.37

GO:0005737

cytoplasm

0.35

EC:6

GO:0016874

tr|T1G910|T1G910_HELRO
Uncharacterized protein
Search

0.52	GO:0006366	transcription by RNA polymerase II
0.52	GO:0045944	positive regulation of transcription by RNA polymerase II
0.49	GO:0007617	mating behavior
0.49	GO:0042698	ovulation cycle
0.36	GO:0030154	cell differentiation
0.36	GO:0007275	multicellular organism development
0.34	GO:0051091	positive regulation of DNA binding transcription factor activity

0.68	GO:0046983	protein dimerization activity
0.55	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.55	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.50	GO:0001102	RNA polymerase II activating transcription factor binding
0.47	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.47	GO:0000987	proximal promoter sequence-specific DNA binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.42	GO:0005634	nucleus
0.33	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

tr|T1G911|T1G911_HELRO
Uncharacterized protein
Search

STK11

0.40	Serine/threonine-protein kinase

0.63	GO:0006468	protein phosphorylation
0.54	GO:0036399	TCR signalosome assembly
0.53	GO:0071493	cellular response to UV-B
0.53	GO:0043276	anoikis
0.52	GO:1903846	positive regulation of cellular response to transforming growth factor beta stimulus
0.52	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development
0.52	GO:0045059	positive thymic T cell selection
0.52	GO:0097484	dendrite extension
0.52	GO:0007163	establishment or maintenance of cell polarity
0.51	GO:0051645	Golgi localization

0.66	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0030275	LRR domain binding
0.52	GO:0030295	protein kinase activator activity
0.51	GO:0002039	p53 binding
0.43	GO:0000287	magnesium ion binding
0.34	GO:0019901	protein kinase binding

0.53	GO:0036398	TCR signalosome
0.45	GO:0005829	cytosol
0.45	GO:0005654	nucleoplasm
0.42	GO:0005739	mitochondrion
0.41	GO:0005938	cell cortex
0.34	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.66

GO:0004674

tr|T1G912|T1G912_HELRO
Uncharacterized protein
Search

0.96	polypyrimidine tract-binding protein 1-like isoform X9

0.69	GO:0006397	mRNA processing
0.48	GO:0007319	negative regulation of oskar mRNA translation
0.48	GO:0008103	oocyte microtubule cytoskeleton polarization
0.47	GO:0008586	imaginal disc-derived wing vein morphogenesis
0.47	GO:0007291	sperm individualization
0.47	GO:0008587	imaginal disc-derived wing margin morphogenesis
0.36	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile

0.59	GO:0003723	RNA binding
0.47	GO:0000900	translation repressor activity, nucleic acid binding

0.61	GO:0005634	nucleus
0.39	GO:0030529	intracellular ribonucleoprotein complex
0.39	GO:0005829	cytosol

tr|T1G913|T1G913_HELRO
Uncharacterized protein
Search

0.56	Serine incorporator 5

0.72	GO:0006658	phosphatidylserine metabolic process
0.68	GO:0006665	sphingolipid metabolic process
0.54	GO:0042552	myelination
0.48	GO:0015825	L-serine transport
0.41	GO:0009597	detection of virus
0.39	GO:1904219	positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity
0.39	GO:1904222	positive regulation of serine C-palmitoyltransferase activity
0.38	GO:0045087	innate immune response
0.38	GO:0051607	defense response to virus
0.33	GO:0006487	protein N-linked glycosylation

0.48	GO:0015194	L-serine transmembrane transporter activity
0.33	GO:0030674	protein binding, bridging
0.32	GO:0008270	zinc ion binding
0.32	GO:0003676	nucleic acid binding

0.49	GO:0005789	endoplasmic reticulum membrane
0.39	GO:0043209	myelin sheath
0.37	GO:0005794	Golgi apparatus
0.35	GO:0005886	plasma membrane
0.35	GO:0070062	extracellular exosome
0.33	GO:1990234	transferase complex
0.30	GO:0016021	integral component of membrane

tr|T1G914|T1G914_HELRO
Uncharacterized protein
Search

0.11	Pyridoxal-dependent decarboxylase domain-containing protein 1

0.55	GO:0019752	carboxylic acid metabolic process
0.43	GO:0098507	polynucleotide 5' dephosphorylation
0.37	GO:0032502	developmental process
0.36	GO:0060255	regulation of macromolecule metabolic process
0.36	GO:0031323	regulation of cellular metabolic process
0.36	GO:0051171	regulation of nitrogen compound metabolic process
0.36	GO:0080090	regulation of primary metabolic process
0.36	GO:0010918	positive regulation of mitochondrial membrane potential
0.36	GO:0036474	cell death in response to hydrogen peroxide
0.36	GO:0097468	programmed cell death in response to reactive oxygen species

0.65	GO:0016831	carboxy-lyase activity
0.63	GO:0030170	pyridoxal phosphate binding
0.43	GO:0004651	polynucleotide 5'-phosphatase activity
0.36	GO:0003700	DNA binding transcription factor activity
0.36	GO:0004676	3-phosphoinositide-dependent protein kinase activity
0.35	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting
0.35	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.35	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity
0.34	GO:0004842	ubiquitin-protein transferase activity
0.34	GO:0044212	transcription regulatory region DNA binding

0.35	GO:0005615	extracellular space
0.35	GO:0005634	nucleus
0.35	GO:0020011	apicoplast
0.34	GO:0005829	cytosol
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.65	EC:4.1.1	GO:0016831
0.35	KEGG:R03469	GO:0016308

tr|T1G915|T1G915_HELRO
Uncharacterized protein
Search

SEC24C

0.72	SEC24 homolog C, COPII coat complex component

0.78	GO:0006888	ER to Golgi vesicle-mediated transport
0.69	GO:0006886	intracellular protein transport
0.64	GO:0035459	cargo loading into vesicle
0.61	GO:0051668	localization within membrane
0.60	GO:0048194	Golgi vesicle budding
0.58	GO:0001701	in utero embryonic development

0.63	GO:0008270	zinc ion binding
0.60	GO:0000149	SNARE binding

0.80	GO:0030127	COPII vesicle coat
0.55	GO:0000139	Golgi membrane
0.52	GO:0005829	cytosol

tr|T1G916|T1G916_HELRO
Uncharacterized protein
Search

NOP58

0.83	Nucleolar protein 58

0.59	GO:0048254	snoRNA localization
0.53	GO:0006364	rRNA processing
0.50	GO:0009451	RNA modification
0.42	GO:0034471	ncRNA 5'-end processing
0.41	GO:0042274	ribosomal small subunit biogenesis
0.40	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic

0.65	GO:0030515	snoRNA binding
0.58	GO:0001094	TFIID-class transcription factor binding
0.56	GO:0051117	ATPase binding
0.43	GO:0017069	snRNA binding
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.65	GO:0005732	small nucleolar ribonucleoprotein complex
0.64	GO:0044452	nucleolar part
0.60	GO:0032040	small-subunit processome
0.58	GO:0070761	pre-snoRNP complex
0.56	GO:0015030	Cajal body
0.54	GO:0019013	viral nucleocapsid
0.48	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|T1G917|T1G917_HELRO
Uncharacterized protein
Search

APEX2

0.42	DNA-(apurinic or apyrimidinic site) lyase

0.65	GO:0006281	DNA repair
0.64	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.35	GO:1902546	positive regulation of DNA N-glycosylase activity
0.34	GO:0007049	cell cycle
0.34	GO:0006310	DNA recombination
0.33	GO:0034614	cellular response to reactive oxygen species
0.33	GO:0006265	DNA topological change
0.32	GO:0071897	DNA biosynthetic process
0.32	GO:0055114	oxidation-reduction process

0.72	GO:0140080	class III/IV DNA-(apurinic or apyrimidinic site) lyase activity
0.72	GO:0140078	class I DNA-(apurinic or apyrimidinic site) lyase activity
0.64	GO:0004518	nuclease activity
0.61	GO:0008270	zinc ion binding
0.52	GO:0003677	DNA binding
0.33	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.33	GO:0008081	phosphoric diester hydrolase activity
0.33	GO:0003917	DNA topoisomerase type I activity
0.33	GO:0020037	heme binding
0.33	GO:0005506	iron ion binding

0.54	GO:0005634	nucleus
0.53	GO:0005739	mitochondrion
0.42	GO:0031974	membrane-enclosed lumen
0.40	GO:0043232	intracellular non-membrane-bounded organelle
0.39	GO:0044446	intracellular organelle part
0.33	GO:0031090	organelle membrane
0.33	GO:0031975	envelope
0.32	GO:0042575	DNA polymerase complex
0.30	GO:0031224	intrinsic component of membrane

0.64

EC:3.1

GO:0004518

tr|T1G918|T1G918_HELRO
Uncharacterized protein
Search

0.53	Collapsin response mediator protein 1

0.54	GO:0097485	neuron projection guidance
0.49	GO:0070997	neuron death
0.47	GO:0006208	pyrimidine nucleobase catabolic process
0.46	GO:0007409	axonogenesis
0.44	GO:0019860	uracil metabolic process
0.44	GO:0007010	cytoskeleton organization
0.43	GO:0051642	centrosome localization
0.43	GO:0045747	positive regulation of Notch signaling pathway
0.43	GO:0007613	memory
0.42	GO:0007265	Ras protein signal transduction

0.65	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
0.46	GO:0051219	phosphoprotein binding
0.40	GO:0008092	cytoskeletal protein binding
0.36	GO:0002059	thymine binding
0.36	GO:0002058	uracil binding
0.35	GO:0046872	metal ion binding
0.34	GO:0016597	amino acid binding
0.33	GO:0016780	phosphotransferase activity, for other substituted phosphate groups

0.48	GO:0005737	cytoplasm
0.35	GO:0005615	extracellular space
0.34	GO:1903561	extracellular vesicle
0.34	GO:0043231	intracellular membrane-bounded organelle
0.33	GO:0031967	organelle envelope
0.30	GO:0016020	membrane

0.65

EC:3.5

GO:0016810

tr|T1G919|T1G919_HELRO
Uncharacterized protein
Search

0.20	Abhydrolase domain-containing protein 4

0.41	GO:0010891	negative regulation of sequestering of triglyceride
0.41	GO:0051006	positive regulation of lipoprotein lipase activity
0.41	GO:0010898	positive regulation of triglyceride catabolic process
0.39	GO:0006654	phosphatidic acid biosynthetic process
0.36	GO:0036152	phosphatidylethanolamine acyl-chain remodeling
0.35	GO:0006275	regulation of DNA replication
0.34	GO:0016042	lipid catabolic process

0.49	GO:0016746	transferase activity, transferring acyl groups
0.44	GO:0016787	hydrolase activity

0.40	GO:0005811	lipid droplet
0.37	GO:0005829	cytosol
0.34	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

0.49

EC:2.3

GO:0016746

tr|T1G920|T1G920_HELRO
Uncharacterized protein
Search

0.37	Transmembrane protein 115

0.81	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.47	GO:0006486	protein glycosylation
0.34	GO:0001302	replicative cell aging
0.34	GO:0015031	protein transport
0.34	GO:0008285	negative regulation of cell proliferation
0.34	GO:0006888	ER to Golgi vesicle-mediated transport

0.47

GO:0042802

identical protein binding

0.50	GO:0017119	Golgi transport complex
0.50	GO:0032580	Golgi cisterna membrane
0.43	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

tr|T1G921|T1G921_HELRO
Uncharacterized protein
Search

0.84	Heterogeneous nuclear ribonucleoprotein D like

0.39	GO:1905663	positive regulation of telomerase RNA reverse transcriptase activity
0.38	GO:0097167	circadian regulation of translation
0.38	GO:1904355	positive regulation of telomere capping
0.37	GO:0043488	regulation of mRNA stability
0.37	GO:0042752	regulation of circadian rhythm
0.36	GO:0045727	positive regulation of translation
0.35	GO:0006351	transcription, DNA-templated
0.35	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:0035722	interleukin-12-mediated signaling pathway
0.33	GO:0016071	mRNA metabolic process

0.59	GO:0003723	RNA binding
0.37	GO:0042162	telomeric DNA binding
0.35	GO:0003697	single-stranded DNA binding
0.35	GO:0003690	double-stranded DNA binding
0.32	GO:0005515	protein binding

0.59	GO:0019013	viral nucleocapsid
0.52	GO:0030529	intracellular ribonucleoprotein complex
0.45	GO:0005654	nucleoplasm
0.35	GO:0070062	extracellular exosome
0.34	GO:0005737	cytoplasm

tr|T1G922|T1G922_HELRO
Uncharacterized protein
Search

0.58	DNA repair and recombination protein RAD54B

0.39	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.36	GO:0051716	cellular response to stimulus
0.36	GO:0008340	determination of adult lifespan
0.36	GO:0010212	response to ionizing radiation
0.36	GO:0023052	signaling
0.36	GO:0007154	cell communication
0.35	GO:0016569	covalent chromatin modification
0.35	GO:0043044	ATP-dependent chromatin remodeling
0.35	GO:0065007	biological regulation
0.35	GO:0042493	response to drug

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0004386	helicase activity
0.38	GO:0005509	calcium ion binding
0.37	GO:0003924	GTPase activity
0.37	GO:0032550	purine ribonucleoside binding
0.37	GO:0019001	guanyl nucleotide binding
0.34	GO:0016887	ATPase activity
0.34	GO:0003677	DNA binding

0.35	GO:0016589	NURF complex
0.34	GO:0005886	plasma membrane
0.34	GO:0034457	Mpp10 complex
0.34	GO:0005732	small nucleolar ribonucleoprotein complex
0.32	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.34

GO:0016887

tr|T1G923|T1G923_HELRO
Uncharacterized protein
Search

0.17	Short-chain dehydrogenase

0.51	GO:0055114	oxidation-reduction process
0.35	GO:0045150	acetoin catabolic process

0.52	GO:0016491	oxidoreductase activity
0.36	GO:0004312	fatty acid synthase activity

0.30

GO:0044425

membrane part

0.52

GO:0016491

tr|T1G924|T1G924_HELRO
Uncharacterized protein
Search

0.61	Nucleolar complex protein 3

0.74	GO:0045444	fat cell differentiation
0.49	GO:0007517	muscle organ development
0.48	GO:0019216	regulation of lipid metabolic process
0.37	GO:1902299	pre-replicative complex assembly involved in cell cycle DNA replication
0.36	GO:0033260	nuclear DNA replication
0.35	GO:0006270	DNA replication initiation
0.35	GO:0006364	rRNA processing

0.58	GO:0003682	chromatin binding
0.36	GO:0003723	RNA binding
0.32	GO:0003677	DNA binding

0.71	GO:0016607	nuclear speck
0.67	GO:0005730	nucleolus
0.54	GO:0005739	mitochondrion
0.37	GO:0030691	Noc2p-Noc3p complex
0.37	GO:0005656	nuclear pre-replicative complex
0.30	GO:0016020	membrane

tr|T1G925|T1G925_HELRO
Uncharacterized protein
Search

DNAAF4

0.90	Dynein axonemal assembly factor 4

0.77	GO:0003341	cilium movement
0.59	GO:0007368	determination of left/right symmetry
0.58	GO:0036158	outer dynein arm assembly
0.58	GO:0033146	regulation of intracellular estrogen receptor signaling pathway
0.57	GO:0036159	inner dynein arm assembly
0.54	GO:0061136	regulation of proteasomal protein catabolic process
0.45	GO:0070986	left/right axis specification
0.44	GO:0001764	neuron migration
0.40	GO:0007464	R3/R4 cell fate commitment
0.40	GO:0007426	tracheal outgrowth, open tracheal system

0.58	GO:0030331	estrogen receptor binding
0.39	GO:0043565	sequence-specific DNA binding
0.37	GO:0042803	protein homodimerization activity
0.36	GO:0003700	DNA binding transcription factor activity
0.36	GO:0003723	RNA binding
0.35	GO:0008168	methyltransferase activity
0.35	GO:0005484	SNAP receptor activity
0.34	GO:0050825	ice binding
0.34	GO:0008140	cAMP response element binding protein binding
0.34	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity

0.48	GO:0005829	cytosol
0.48	GO:0005634	nucleus
0.42	GO:0005886	plasma membrane
0.40	GO:0097730	non-motile cilium
0.39	GO:0005813	centrosome
0.35	GO:0070013	intracellular organelle lumen
0.33	GO:1990124	messenger ribonucleoprotein complex
0.33	GO:0005700	polytene chromosome
0.33	GO:0043186	P granule
0.33	GO:0017053	transcriptional repressor complex

0.35

GO:0008168

tr|T1G926|T1G926_HELRO
Uncharacterized protein
Search

CDK7

0.71	Cyclin-dependent kinase

0.63	GO:0006468	protein phosphorylation
0.49	GO:0045944	positive regulation of transcription by RNA polymerase II
0.48	GO:0050821	protein stabilization
0.46	GO:0006366	transcription by RNA polymerase II
0.46	GO:0051301	cell division
0.43	GO:0051726	regulation of cell cycle
0.35	GO:0006294	nucleotide-excision repair, preincision complex assembly
0.35	GO:1900195	positive regulation of oocyte maturation
0.35	GO:0006362	transcription elongation from RNA polymerase I promoter
0.35	GO:0006363	termination of RNA polymerase I transcription

0.84	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0008022	protein C-terminus binding
0.46	GO:0004693	cyclin-dependent protein serine/threonine kinase activity
0.44	GO:0008094	DNA-dependent ATPase activity
0.35	GO:0050681	androgen receptor binding
0.35	GO:0004689	phosphorylase kinase activity

0.84	GO:0070985	TFIIK complex
0.51	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex
0.36	GO:0005737	cytoplasm
0.35	GO:0042585	germinal vesicle
0.34	GO:0031312	extrinsic component of organelle membrane
0.33	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.84

EC:2.7.11.23

GO:0008353

tr|T1G927|T1G927_HELRO
Uncharacterized protein
Search

0.66	GO:0030001	metal ion transport
0.55	GO:0055085	transmembrane transport
0.48	GO:0043029	T cell homeostasis
0.48	GO:0072511	divalent inorganic cation transport
0.47	GO:0048701	embryonic cranial skeleton morphogenesis
0.47	GO:0060173	limb development
0.44	GO:0000902	cell morphogenesis
0.43	GO:0001701	in utero embryonic development
0.42	GO:0010312	detoxification of zinc ion
0.35	GO:0051382	kinetochore assembly

0.68	GO:0046873	metal ion transmembrane transporter activity
0.51	GO:0072509	divalent inorganic cation transmembrane transporter activity
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003677	DNA binding
0.32	GO:0004672	protein kinase activity
0.32	GO:0003700	DNA binding transcription factor activity

0.40	GO:0016323	basolateral plasma membrane
0.40	GO:0016324	apical plasma membrane
0.35	GO:0000776	kinetochore
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

tr|T1G928|T1G928_HELRO
Uncharacterized protein
Search

0.22	1-acyl-sn-glycerol-3-phosphate acyltransferase

0.68	GO:0008654	phospholipid biosynthetic process
0.40	GO:0045017	glycerolipid biosynthetic process
0.39	GO:0006650	glycerophospholipid metabolic process

0.80

GO:0003841

1-acylglycerol-3-phosphate O-acyltransferase activity

0.40	GO:0005811	lipid droplet
0.30	GO:0031224	intrinsic component of membrane

0.80

EC:2.3.1.51

GO:0003841

tr|T1G929|T1G929_HELRO
Protein disulfide-isomerase
Search

PDIA4

0.57	Protein disulfide-isomerase

0.69	GO:0045454	cell redox homeostasis
0.48	GO:0034976	response to endoplasmic reticulum stress
0.45	GO:0006457	protein folding
0.41	GO:0055114	oxidation-reduction process
0.37	GO:1903334	positive regulation of protein folding
0.34	GO:0009306	protein secretion

0.81	GO:0003756	protein disulfide isomerase activity
0.56	GO:0015037	peptide disulfide oxidoreductase activity
0.35	GO:0005515	protein binding
0.34	GO:0003676	nucleic acid binding

0.74	GO:0005788	endoplasmic reticulum lumen
0.53	GO:0009986	cell surface
0.52	GO:0005615	extracellular space
0.41	GO:0042470	melanosome
0.38	GO:0034663	endoplasmic reticulum chaperone complex
0.36	GO:0005790	smooth endoplasmic reticulum
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0045335	phagocytic vesicle
0.30	GO:0031224	intrinsic component of membrane

0.81

EC:5.3.4.1

GO:0003756

tr|T1G930|T1G930_HELRO
Uncharacterized protein
Search

PRPF8

0.79	Pre-mRNA-processing-splicing factor

0.75	GO:0000398	mRNA splicing, via spliceosome
0.52	GO:0022618	ribonucleoprotein complex assembly
0.38	GO:0007283	spermatogenesis
0.37	GO:0071356	cellular response to tumor necrosis factor
0.37	GO:0071222	cellular response to lipopolysaccharide

0.85	GO:0030623	U5 snRNA binding
0.85	GO:0017070	U6 snRNA binding
0.53	GO:0070530	K63-linked polyubiquitin modification-dependent protein binding
0.47	GO:0097157	pre-mRNA intronic binding
0.47	GO:0030620	U2 snRNA binding
0.47	GO:0000386	second spliceosomal transesterification activity
0.46	GO:0030619	U1 snRNA binding
0.33	GO:0046983	protein dimerization activity

0.76	GO:0005681	spliceosomal complex
0.53	GO:0030532	small nuclear ribonucleoprotein complex
0.44	GO:1902494	catalytic complex
0.36	GO:0016607	nuclear speck
0.33	GO:0005737	cytoplasm
0.33	GO:0019013	viral nucleocapsid
0.30	GO:0016020	membrane

tr|T1G931|T1G931_HELRO
Uncharacterized protein
Search

tr|T1G932|T1G932_HELRO
Uncharacterized protein
Search

0.48	E3 ubiquitin-protein ligase (inferred by orthology to a C. elegans protein)

0.73	GO:0016567	protein ubiquitination
0.71	GO:0006511	ubiquitin-dependent protein catabolic process
0.50	GO:0010498	proteasomal protein catabolic process
0.49	GO:0006858	extracellular transport
0.48	GO:1901016	regulation of potassium ion transmembrane transporter activity
0.48	GO:0032410	negative regulation of transporter activity
0.48	GO:0043433	negative regulation of DNA binding transcription factor activity
0.47	GO:0051224	negative regulation of protein transport
0.46	GO:0000122	negative regulation of transcription by RNA polymerase II
0.46	GO:0042391	regulation of membrane potential

0.74	GO:0061630	ubiquitin protein ligase activity
0.51	GO:0016874	ligase activity
0.48	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.48	GO:0001085	RNA polymerase II transcription factor binding
0.39	GO:0005112	Notch binding
0.38	GO:0019904	protein domain specific binding

0.42	GO:0005576	extracellular region
0.41	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm
0.35	GO:0031982	vesicle
0.34	GO:0071944	cell periphery
0.30	GO:0016020	membrane

0.51

EC:6

GO:0016874

tr|T1G933|T1G933_HELRO
Tubulin alpha chain
Search

0.53	Tubulin alpha chain

0.72	GO:0007017	microtubule-based process
0.71	GO:0007010	cytoskeleton organization
0.34	GO:0021782	glial cell development
0.34	GO:0042552	myelination
0.34	GO:0030705	cytoskeleton-dependent intracellular transport
0.33	GO:0051301	cell division
0.32	GO:0055085	transmembrane transport

0.77	GO:0005200	structural constituent of cytoskeleton
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005515	protein binding
0.33	GO:0042626	ATPase activity, coupled to transmembrane movement of substances

0.73	GO:0005874	microtubule
0.47	GO:0005737	cytoplasm
0.35	GO:0031982	vesicle
0.34	GO:0045121	membrane raft
0.34	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

tr|T1G934|T1G934_HELRO
Phosphoinositide phospholipase C
Search

0.41	Phosphoinositide phospholipase C

0.72	GO:0016042	lipid catabolic process
0.62	GO:0035556	intracellular signal transduction
0.55	GO:0001525	angiogenesis
0.52	GO:0042127	regulation of cell proliferation
0.52	GO:0060716	labyrinthine layer blood vessel development
0.40	GO:0007338	single fertilization
0.38	GO:0032228	regulation of synaptic transmission, GABAergic
0.36	GO:0046488	phosphatidylinositol metabolic process
0.36	GO:0001775	cell activation
0.36	GO:0006816	calcium ion transport

0.81	GO:0004435	phosphatidylinositol phospholipase C activity
0.66	GO:0005509	calcium ion binding
0.63	GO:0004871	signal transducer activity
0.52	GO:0032794	GTPase activating protein binding
0.51	GO:0070300	phosphatidic acid binding
0.51	GO:0001786	phosphatidylserine binding
0.51	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.40	GO:0050429	calcium-dependent phospholipase C activity
0.38	GO:0050811	GABA receptor binding
0.38	GO:0070679	inositol 1,4,5 trisphosphate binding

0.45	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.81	EC:3.1.4.11	GO:0004435
0.81	KEGG:R03435	GO:0004435

tr|T1G935|T1G935_HELRO
Uncharacterized protein
Search

0.64	ATP-dependent DNA helicase Q4 (Fragment)

0.61	GO:0006310	DNA recombination
0.48	GO:0006302	double-strand break repair
0.48	GO:0007307	eggshell chorion gene amplification
0.47	GO:0036292	DNA rewinding
0.47	GO:0006284	base-excision repair
0.46	GO:0032508	DNA duplex unwinding
0.46	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle
0.46	GO:0045740	positive regulation of DNA replication
0.45	GO:0002164	larval development
0.45	GO:0008284	positive regulation of cell proliferation

0.65	GO:0070035	purine NTP-dependent helicase activity
0.60	GO:0008270	zinc ion binding
0.59	GO:0042623	ATPase activity, coupled
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0003676	nucleic acid binding
0.50	GO:0043138	3'-5' DNA helicase activity
0.44	GO:0009378	four-way junction helicase activity
0.34	GO:0003682	chromatin binding

0.45	GO:0005694	chromosome
0.44	GO:0005634	nucleus
0.39	GO:0044446	intracellular organelle part
0.38	GO:0005737	cytoplasm
0.34	GO:0005834	heterotrimeric G-protein complex
0.30	GO:0031224	intrinsic component of membrane

tr|T1G936|T1G936_HELRO
Uncharacterized protein
Search

0.76

Lamin

0.35	GO:1902365	positive regulation of protein localization to spindle pole body
0.35	GO:0055048	anastral spindle assembly
0.35	GO:0051049	regulation of transport
0.35	GO:0097435	supramolecular fiber organization
0.35	GO:0110028	positive regulation of mitotic spindle organization
0.35	GO:1905832	positive regulation of spindle assembly
0.35	GO:0045104	intermediate filament cytoskeleton organization
0.35	GO:1904778	positive regulation of protein localization to cell cortex
0.35	GO:0045618	positive regulation of keratinocyte differentiation
0.35	GO:0051798	positive regulation of hair follicle development

0.61	GO:0005198	structural molecule activity
0.34	GO:0051011	microtubule minus-end binding
0.34	GO:0097718	disordered domain specific binding
0.34	GO:0051010	microtubule plus-end binding
0.34	GO:0070840	dynein complex binding
0.34	GO:0008022	protein C-terminus binding
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.34	GO:0035091	phosphatidylinositol binding
0.33	GO:0005509	calcium ion binding
0.32	GO:0030554	adenyl nucleotide binding

0.78	GO:0005882	intermediate filament
0.38	GO:0036338	viral membrane
0.36	GO:0012505	endomembrane system
0.36	GO:0044428	nuclear part
0.35	GO:1905720	cytoplasmic microtubule bundle
0.35	GO:0061673	mitotic spindle astral microtubule
0.35	GO:0097575	lateral cell cortex
0.35	GO:0036449	microtubule minus-end
0.35	GO:0055028	cortical microtubule
0.34	GO:0031616	spindle pole centrosome

0.34	EC:1.3.1.74	GO:0032440
0.32	KEGG:R03876	GO:0004842

tr|T1G937|T1G937_HELRO
Uncharacterized protein
Search

0.70	Cholinergic receptor nicotinic alpha 7 subunit

0.74	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.37	GO:0035094	response to nicotine
0.34	GO:0001988	positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure
0.34	GO:1905920	positive regulation of CoA-transferase activity
0.34	GO:0060112	generation of ovulation cycle rhythm
0.34	GO:0050893	sensory processing
0.34	GO:0014061	regulation of norepinephrine secretion
0.34	GO:0140059	dendrite arborization
0.34	GO:1905906	regulation of amyloid fibril formation

0.77	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0004888	transmembrane signaling receptor activity
0.33	GO:0022850	serotonin-gated cation-selective channel activity
0.33	GO:0003777	microtubule motor activity
0.33	GO:0008017	microtubule binding
0.33	GO:0003779	actin binding
0.33	GO:0005509	calcium ion binding
0.32	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0008270	zinc ion binding

0.74	GO:0045211	postsynaptic membrane
0.69	GO:0030054	cell junction
0.46	GO:0043204	perikaryon
0.45	GO:0030424	axon
0.44	GO:0030425	dendrite
0.36	GO:0005892	acetylcholine-gated channel complex
0.36	GO:0005737	cytoplasm
0.34	GO:0032589	neuron projection membrane
0.33	GO:0009897	external side of plasma membrane
0.33	GO:0016324	apical plasma membrane

0.32

EC:2.3.1

GO:0016747

tr|T1G938|T1G938_HELRO
Uncharacterized protein
Search

tr|T1G939|T1G939_HELRO
Sodium/potassium-transporting ATPase subunit alpha
Search

0.64	Sodium/potassium-transporting ATPase subunit alpha

0.84	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient
0.75	GO:0090662	ATP hydrolysis coupled transmembrane transport
0.72	GO:0006814	sodium ion transport
0.71	GO:0006813	potassium ion transport
0.37	GO:0030317	flagellated sperm motility
0.37	GO:0030641	regulation of cellular pH
0.37	GO:0009566	fertilization
0.37	GO:0007283	spermatogenesis
0.36	GO:0042391	regulation of membrane potential
0.32	GO:0016310	phosphorylation

0.84	GO:0005391	sodium:potassium-exchanging ATPase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0046872	metal ion binding
0.33	GO:0016301	kinase activity

0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.84

EC:3.6.3.9

GO:0005391

tr|T1G940|T1G940_HELRO
Sodium/potassium-transporting ATPase subunit alpha
Search

0.64	Sodium/potassium-transporting ATPase subunit alpha-B

0.85	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient
0.76	GO:0090662	ATP hydrolysis coupled transmembrane transport
0.73	GO:0006814	sodium ion transport
0.71	GO:0006813	potassium ion transport
0.42	GO:1903416	response to glycoside
0.41	GO:0031947	negative regulation of glucocorticoid biosynthetic process
0.41	GO:0008015	blood circulation
0.41	GO:0045989	positive regulation of striated muscle contraction
0.41	GO:0006883	cellular sodium ion homeostasis
0.41	GO:0086009	membrane repolarization

0.85	GO:0005391	sodium:potassium-exchanging ATPase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.53	GO:0046872	metal ion binding
0.41	GO:1990239	steroid hormone binding
0.39	GO:0051087	chaperone binding
0.37	GO:0016791	phosphatase activity
0.36	GO:0030506	ankyrin binding

0.41	GO:0042383	sarcolemma
0.40	GO:0005890	sodium:potassium-exchanging ATPase complex
0.40	GO:0014069	postsynaptic density
0.39	GO:0043209	myelin sheath
0.39	GO:0016323	basolateral plasma membrane
0.39	GO:0016324	apical plasma membrane
0.36	GO:0014704	intercalated disc
0.36	GO:0005901	caveola
0.35	GO:0043234	protein complex
0.35	GO:0005768	endosome

0.85

EC:3.6.3.9

GO:0005391

tr|T1G941|T1G941_HELRO
Uncharacterized protein
Search

0.48	Water-specific aquaporin

0.55	GO:0055085	transmembrane transport
0.47	GO:0006833	water transport
0.43	GO:0006863	purine nucleobase transport
0.42	GO:0071320	cellular response to cAMP
0.42	GO:0015837	amine transport
0.41	GO:0015791	polyol transport
0.41	GO:0046689	response to mercury ion
0.41	GO:0015855	pyrimidine nucleobase transport
0.35	GO:0006811	ion transport
0.35	GO:1990349	gap junction-mediated intercellular transport

0.69	GO:0022803	passive transmembrane transporter activity
0.47	GO:0005372	water transmembrane transporter activity
0.43	GO:0005345	purine nucleobase transmembrane transporter activity
0.41	GO:0005350	pyrimidine nucleobase transmembrane transporter activity
0.35	GO:0015168	glycerol transmembrane transporter activity
0.35	GO:0015204	urea transmembrane transporter activity
0.34	GO:0005212	structural constituent of eye lens
0.33	GO:0005515	protein binding
0.33	GO:0008509	anion transmembrane transporter activity
0.32	GO:0005275	amine transmembrane transporter activity

0.37	GO:0098590	plasma membrane region
0.37	GO:0005887	integral component of plasma membrane
0.36	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0005921	gap junction
0.34	GO:0045177	apical part of cell
0.33	GO:0012505	endomembrane system
0.33	GO:0046930	pore complex
0.33	GO:0098805	whole membrane
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0044444	cytoplasmic part

tr|T1G942|T1G942_HELRO
Innexin
Search

INX

0.64	Innexin unc-9

0.59	GO:0006811	ion transport
0.36	GO:0010644	cell communication by electrical coupling
0.34	GO:0048598	embryonic morphogenesis
0.33	GO:0055085	transmembrane transport
0.33	GO:0007186	G-protein coupled receptor signaling pathway

0.38	GO:0005243	gap junction channel activity
0.33	GO:0004930	G-protein coupled receptor activity

0.81	GO:0005921	gap junction
0.55	GO:0005886	plasma membrane
0.34	GO:0045202	synapse
0.32	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

tr|T1G943|T1G943_HELRO
Diacylglycerol kinase
Search

0.47	Diacylglycerol kinase

0.83	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway
0.61	GO:0035556	intracellular signal transduction
0.57	GO:0016310	phosphorylation
0.41	GO:0048366	leaf development
0.40	GO:0048364	root development
0.40	GO:0009611	response to wounding
0.34	GO:0035725	sodium ion transmembrane transport
0.33	GO:0009409	response to cold
0.33	GO:0006952	defense response

0.80	GO:0004143	diacylglycerol kinase activity
0.75	GO:0003951	NAD+ kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005272	sodium channel activity
0.33	GO:0005509	calcium ion binding

0.44	GO:0005622	intracellular
0.30	GO:0016020	membrane

0.80	EC:2.7.1.107	GO:0004143
0.75	KEGG:R00104	GO:0003951

tr|T1G944|T1G944_HELRO
S-(hydroxymethyl)glutathione dehydrogenase
Search

ADH5

0.59	S-(hydroxymethyl)glutathione dehydrogenase

0.82	GO:0006069	ethanol oxidation
0.50	GO:0018119	peptidyl-cysteine S-nitrosylation
0.49	GO:0003016	respiratory system process
0.49	GO:0045777	positive regulation of blood pressure
0.48	GO:0051775	response to redox state
0.48	GO:0001523	retinoid metabolic process
0.48	GO:0051409	response to nitrosative stress
0.47	GO:0032496	response to lipopolysaccharide
0.46	GO:0046294	formaldehyde catabolic process
0.35	GO:0042254	ribosome biogenesis

0.82	GO:0051903	S-(hydroxymethyl)glutathione dehydrogenase activity
0.63	GO:0008270	zinc ion binding
0.51	GO:0018467	formaldehyde dehydrogenase activity
0.50	GO:0005504	fatty acid binding
0.48	GO:0004022	alcohol dehydrogenase (NAD) activity
0.45	GO:0042803	protein homodimerization activity
0.33	GO:0009055	electron transfer activity
0.33	GO:0003723	RNA binding

0.40	GO:0005739	mitochondrion
0.36	GO:0005730	nucleolus
0.36	GO:0070062	extracellular exosome
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.82	EC:1.1.1.284	GO:0051903
0.82	KEGG:R06983 KEGG:R07140	GO:0051903

tr|T1G945|T1G945_HELRO
Uncharacterized protein
Search

0.45	Transmembrane protein 45A

0.40

GO:0005887

integral component of plasma membrane

tr|T1G946|T1G946_HELRO
Uncharacterized protein
Search

0.74	GO:0006955	immune response
0.72	GO:0006898	receptor-mediated endocytosis

0.81	GO:0005044	scavenger receptor activity
0.78	GO:0030247	polysaccharide binding

0.30

GO:0044425

membrane part

tr|T1G947|T1G947_HELRO
Uncharacterized protein
Search

0.71	Four and a half lim domains

0.41

GO:0050832

defense response to fungus

0.54	GO:0046872	metal ion binding
0.39	GO:0019904	protein domain specific binding

0.41	GO:0031430	M band
0.30	GO:0044425	membrane part

tr|T1G948|T1G948_HELRO
Uncharacterized protein
Search

tr|T1G949|T1G949_HELRO
Uncharacterized protein
Search

0.39	GO:1903506	regulation of nucleic acid-templated transcription
0.39	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.39	GO:0010468	regulation of gene expression
0.34	GO:0009909	regulation of flower development
0.34	GO:0050832	defense response to fungus
0.34	GO:0006351	transcription, DNA-templated
0.34	GO:0007018	microtubule-based movement
0.34	GO:1902679	negative regulation of RNA biosynthetic process
0.34	GO:0051716	cellular response to stimulus
0.33	GO:0006413	translational initiation

0.50	GO:0003676	nucleic acid binding
0.38	GO:0046872	metal ion binding
0.35	GO:0003700	DNA binding transcription factor activity
0.35	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.34	GO:0005515	protein binding
0.34	GO:0003777	microtubule motor activity
0.33	GO:0005543	phospholipid binding
0.33	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity
0.33	GO:0004588	orotate phosphoribosyltransferase activity
0.33	GO:0004590	orotidine-5'-phosphate decarboxylase activity

0.37	GO:0005634	nucleus
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part
0.33	GO:0032991	macromolecular complex
0.33	GO:0005694	chromosome
0.33	GO:0099512	supramolecular fiber
0.33	GO:0015630	microtubule cytoskeleton
0.32	GO:0019898	extrinsic component of membrane
0.32	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.35	EC:3.1.4.17	GO:0004114
0.33	KEGG:R00965	GO:0004590

tr|T1G950|T1G950_HELRO
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B
Search

0.66	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B

0.79	GO:0043666	regulation of phosphoprotein phosphatase activity
0.43	GO:0070262	peptidyl-serine dephosphorylation
0.41	GO:0000278	mitotic cell cycle
0.39	GO:0032502	developmental process
0.35	GO:0006915	apoptotic process
0.35	GO:0048285	organelle fission
0.34	GO:0043525	positive regulation of neuron apoptotic process
0.34	GO:0032501	multicellular organismal process
0.34	GO:0044770	cell cycle phase transition
0.34	GO:0006626	protein targeting to mitochondrion

0.80	GO:0019888	protein phosphatase regulator activity
0.41	GO:0004722	protein serine/threonine phosphatase activity
0.34	GO:0005515	protein binding
0.33	GO:0044877	macromolecular complex binding

0.81	GO:0000159	protein phosphatase type 2A complex
0.39	GO:0005829	cytosol
0.36	GO:0005856	cytoskeleton
0.35	GO:0005741	mitochondrial outer membrane
0.33	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1G951|T1G951_HELRO
Uncharacterized protein
Search

0.56	actin-binding protein anillin

0.73	GO:0000281	mitotic cytokinesis
0.72	GO:0008356	asymmetric cell division
0.71	GO:0030726	male germline ring canal formation
0.70	GO:1904172	positive regulation of bleb assembly
0.69	GO:0007279	pole cell formation
0.67	GO:0007112	male meiosis cytokinesis
0.67	GO:0032189	maintenance of actomyosin contractile ring localization
0.66	GO:0090521	glomerular visceral epithelial cell migration
0.65	GO:0044837	actomyosin contractile ring organization
0.65	GO:0000912	assembly of actomyosin apparatus involved in cytokinesis

0.68	GO:0003779	actin binding
0.64	GO:0017022	myosin binding
0.60	GO:0045296	cadherin binding
0.58	GO:0032403	protein complex binding
0.58	GO:0008017	microtubule binding

0.77	GO:0005826	actomyosin contractile ring
0.70	GO:0035323	male germline ring canal
0.69	GO:0032059	bleb
0.65	GO:0032154	cleavage furrow
0.62	GO:0099738	cell cortex region
0.60	GO:0030496	midbody
0.57	GO:0005634	nucleus
0.51	GO:0043233	organelle lumen
0.30	GO:0031224	intrinsic component of membrane

tr|T1G952|T1G952_HELRO
Uncharacterized protein
Search

0.50	GO:0031104	dendrite regeneration
0.47	GO:0048678	response to axon injury
0.47	GO:0008347	glial cell migration
0.46	GO:0001764	neuron migration
0.45	GO:0007411	axon guidance
0.44	GO:0030198	extracellular matrix organization
0.41	GO:0007160	cell-matrix adhesion
0.39	GO:0010952	positive regulation of peptidase activity
0.38	GO:0006898	receptor-mediated endocytosis
0.37	GO:0007166	cell surface receptor signaling pathway

0.70	GO:0005509	calcium ion binding
0.53	GO:0005201	extracellular matrix structural constituent
0.40	GO:0016504	peptidase activator activity
0.40	GO:0005044	scavenger receptor activity
0.38	GO:0030246	carbohydrate binding
0.37	GO:0001871	pattern binding
0.36	GO:0008061	chitin binding
0.36	GO:0050840	extracellular matrix binding
0.35	GO:0004867	serine-type endopeptidase inhibitor activity
0.35	GO:0004888	transmembrane signaling receptor activity

0.56	GO:0031012	extracellular matrix
0.45	GO:0005615	extracellular space
0.34	GO:0099512	supramolecular fiber
0.33	GO:0031429	box H/ACA snoRNP complex
0.33	GO:0030056	hemidesmosome
0.33	GO:0005839	proteasome core complex
0.33	GO:0045111	intermediate filament cytoskeleton
0.32	GO:0044430	cytoskeletal part
0.30	GO:0016020	membrane

0.34	EC:1.11.1.7	GO:0004601
0.34	KEGG:R03532	GO:0004601

tr|T1G953|T1G953_HELRO
Uncharacterized protein
Search

ALDH5A1

0.43	Succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase

0.72	GO:0009450	gamma-aminobutyric acid catabolic process
0.53	GO:0055114	oxidation-reduction process
0.46	GO:0006105	succinate metabolic process
0.45	GO:0051289	protein homotetramerization
0.45	GO:0006681	galactosylceramide metabolic process
0.45	GO:0006678	glucosylceramide metabolic process
0.44	GO:0006536	glutamate metabolic process
0.44	GO:0007417	central nervous system development
0.43	GO:0046459	short-chain fatty acid metabolic process
0.43	GO:0009791	post-embryonic development

0.73	GO:0009013	succinate-semialdehyde dehydrogenase [NAD(P)+] activity
0.49	GO:0004777	succinate-semialdehyde dehydrogenase (NAD+) activity
0.38	GO:0051287	NAD binding
0.34	GO:0047949	glutarate-semialdehyde dehydrogenase activity
0.34	GO:0008911	lactaldehyde dehydrogenase activity
0.34	GO:0005388	calcium-transporting ATPase activity
0.33	GO:0042803	protein homodimerization activity
0.33	GO:0031406	carboxylic acid binding
0.32	GO:0005524	ATP binding

0.40	GO:0005739	mitochondrion
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.73

EC:1.2.1.16

GO:0009013

tr|T1G954|T1G954_HELRO
Uncharacterized protein
Search

0.63	Polypeptide N-acetylgalactosaminyltransferase

0.72	GO:0006486	protein glycosylation
0.44	GO:0007049	cell cycle
0.41	GO:0006351	transcription, DNA-templated
0.38	GO:0009312	oligosaccharide biosynthetic process
0.37	GO:0018210	peptidyl-threonine modification
0.35	GO:0001731	formation of translation preinitiation complex
0.35	GO:0006446	regulation of translational initiation
0.34	GO:0018209	peptidyl-serine modification
0.33	GO:1903506	regulation of nucleic acid-templated transcription

0.68	GO:0030246	carbohydrate binding
0.63	GO:0016757	transferase activity, transferring glycosyl groups
0.36	GO:0140096	catalytic activity, acting on a protein
0.35	GO:0043022	ribosome binding
0.35	GO:0003743	translation initiation factor activity
0.34	GO:0008270	zinc ion binding

0.71	GO:0000139	Golgi membrane
0.53	GO:0070176	DRM complex
0.35	GO:0016282	eukaryotic 43S preinitiation complex
0.35	GO:0033290	eukaryotic 48S preinitiation complex
0.35	GO:0005852	eukaryotic translation initiation factor 3 complex
0.34	GO:0005795	Golgi stack
0.30	GO:0031224	intrinsic component of membrane

0.63

EC:2.4

GO:0016757

tr|T1G955|T1G955_HELRO
Uncharacterized protein
Search

0.63	GTP binding protein alpha subunit Go

0.81	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.47	GO:0014045	establishment of endothelial blood-brain barrier
0.47	GO:0042595	behavioral response to starvation
0.47	GO:0060857	establishment of glial blood-brain barrier
0.47	GO:0061343	cell adhesion involved in heart morphogenesis
0.47	GO:0001737	establishment of imaginal disc-derived wing hair orientation
0.46	GO:0019991	septate junction assembly
0.46	GO:0007419	ventral cord development
0.46	GO:0032291	axon ensheathment in central nervous system
0.46	GO:0045886	negative regulation of synaptic growth at neuromuscular junction

0.81	GO:0031683	G-protein beta/gamma-subunit complex binding
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.64	GO:0004871	signal transducer activity
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0001664	G-protein coupled receptor binding
0.35	GO:0046872	metal ion binding

0.45	GO:1905360	GTPase complex
0.45	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.41	GO:0098797	plasma membrane protein complex
0.30	GO:0031224	intrinsic component of membrane

tr|T1G956|T1G956_HELRO
Poly [ADP-ribose] polymerase
Search

PARP1

0.57	Poly [ADP-ribose] polymerase

0.84	GO:0006471	protein ADP-ribosylation
0.49	GO:1990966	ATP generation from poly-ADP-D-ribose
0.49	GO:1903518	positive regulation of single strand break repair
0.48	GO:2001170	negative regulation of ATP biosynthetic process
0.47	GO:0043504	mitochondrial DNA repair
0.47	GO:0018209	peptidyl-serine modification
0.46	GO:0006273	lagging strand elongation
0.46	GO:0032869	cellular response to insulin stimulus
0.46	GO:0034644	cellular response to UV
0.45	GO:0051103	DNA ligation involved in DNA repair

0.82	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.61	GO:0051287	NAD binding
0.60	GO:0008270	zinc ion binding
0.52	GO:0003677	DNA binding
0.52	GO:1990404	protein ADP-ribosylase activity
0.46	GO:0047485	protein N-terminus binding
0.45	GO:0003910	DNA ligase (ATP) activity
0.45	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.44	GO:0019901	protein kinase binding
0.43	GO:0001067	regulatory region nucleic acid binding

0.56	GO:0005634	nucleus
0.43	GO:0005667	transcription factor complex
0.43	GO:0070013	intracellular organelle lumen
0.42	GO:0032993	protein-DNA complex
0.41	GO:0012505	endomembrane system
0.40	GO:0043232	intracellular non-membrane-bounded organelle
0.40	GO:0044446	intracellular organelle part
0.39	GO:0005739	mitochondrion
0.39	GO:0031975	envelope
0.30	GO:0016020	membrane

0.82

EC:2.4.2.30

GO:0003950

tr|T1G957|T1G957_HELRO
Uncharacterized protein
Search

AQP9

0.41

Aquaporin

0.55	GO:0055085	transmembrane transport
0.46	GO:0006833	water transport
0.44	GO:0015791	polyol transport
0.43	GO:0006863	purine nucleobase transport
0.43	GO:0071320	cellular response to cAMP
0.42	GO:0015837	amine transport
0.41	GO:0046689	response to mercury ion
0.41	GO:0015855	pyrimidine nucleobase transport
0.38	GO:0015700	arsenite transport
0.37	GO:0015840	urea transport

0.69	GO:0022803	passive transmembrane transporter activity
0.46	GO:0005372	water transmembrane transporter activity
0.43	GO:0005345	purine nucleobase transmembrane transporter activity
0.41	GO:0005350	pyrimidine nucleobase transmembrane transporter activity
0.40	GO:0015168	glycerol transmembrane transporter activity
0.37	GO:0015204	urea transmembrane transporter activity
0.37	GO:0015105	arsenite transmembrane transporter activity
0.33	GO:0005212	structural constituent of eye lens

0.36	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0005886	plasma membrane
0.34	GO:0097730	non-motile cilium
0.34	GO:0043025	neuronal cell body
0.33	GO:0005921	gap junction
0.32	GO:0012505	endomembrane system
0.32	GO:0044444	cytoplasmic part
0.30	GO:0016021	integral component of membrane

tr|T1G958|T1G958_HELRO
Uncharacterized protein
Search

AMMECR1

0.87	AMME syndrome candidate gene 1

0.33

GO:0035556

intracellular signal transduction

0.36

GO:0005515

protein binding

0.59	GO:0005634	nucleus
0.30	GO:0044425	membrane part

tr|T1G959|T1G959_HELRO
Uncharacterized protein
Search

TTF2

0.72	Transcription termination factor, RNA polymerase II

0.43	GO:0034454	microtubule anchoring at centrosome
0.42	GO:0007143	female meiotic nuclear division
0.41	GO:0007283	spermatogenesis
0.41	GO:0006353	DNA-templated transcription, termination
0.34	GO:0008380	RNA splicing
0.34	GO:0006397	mRNA processing
0.34	GO:0006366	transcription by RNA polymerase II
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0008270	zinc ion binding
0.39	GO:0008094	DNA-dependent ATPase activity
0.36	GO:0004386	helicase activity
0.33	GO:0003677	DNA binding
0.33	GO:0005515	protein binding

0.45	GO:0005829	cytosol
0.38	GO:0005634	nucleus
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part
0.32	GO:0043234	protein complex
0.30	GO:0016020	membrane

tr|T1G960|T1G960_HELRO
Uncharacterized protein
Search

0.61	Glutamate ionotropic receptor AMPA type subunit 3

0.79	GO:0060079	excitatory postsynaptic potential
0.77	GO:0035235	ionotropic glutamate receptor signaling pathway
0.60	GO:0034220	ion transmembrane transport
0.39	GO:0099566	regulation of postsynaptic cytosolic calcium ion concentration
0.39	GO:0060292	long term synaptic depression
0.38	GO:0031623	receptor internalization
0.38	GO:0007616	long-term memory
0.35	GO:0016573	histone acetylation
0.34	GO:0048208	COPII vesicle coating
0.34	GO:0006182	cGMP biosynthetic process

0.81	GO:0005234	extracellularly glutamate-gated ion channel activity
0.77	GO:0004970	ionotropic glutamate receptor activity
0.44	GO:0099094	ligand-gated cation channel activity
0.39	GO:0099583	neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration
0.38	GO:1904315	transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential
0.35	GO:0004402	histone acetyltransferase activity
0.35	GO:0003712	transcription cofactor activity
0.34	GO:0001540	amyloid-beta binding
0.34	GO:0030165	PDZ domain binding
0.34	GO:0004383	guanylate cyclase activity

0.78	GO:0045211	postsynaptic membrane
0.73	GO:0030054	cell junction
0.46	GO:0032281	AMPA glutamate receptor complex
0.39	GO:0044308	axonal spine
0.38	GO:0032590	dendrite membrane
0.38	GO:0043197	dendritic spine
0.38	GO:0014069	postsynaptic density
0.37	GO:0008021	synaptic vesicle
0.37	GO:0043025	neuronal cell body
0.37	GO:0055037	recycling endosome

0.35

GO:0004402

tr|T1G961|T1G961_HELRO
Uncharacterized protein
Search

0.47	JmjC domain-containing protein 4

0.75	GO:0070079	histone H4-R3 demethylation
0.75	GO:0070078	histone H3-R2 demethylation
0.73	GO:0010030	positive regulation of seed germination
0.71	GO:0043985	histone H4-R3 methylation

0.75	GO:0033749	histone demethylase activity (H4-R3 specific)
0.75	GO:0033746	histone demethylase activity (H3-R2 specific)
0.64	GO:0000987	proximal promoter sequence-specific DNA binding

0.51	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

tr|T1G962|T1G962_HELRO
Uncharacterized protein
Search

ASF1A

0.74	Histone chaperone

0.78	GO:0006333	chromatin assembly or disassembly
0.53	GO:0001649	osteoblast differentiation
0.53	GO:0034728	nucleosome organization
0.52	GO:0065004	protein-DNA complex assembly
0.51	GO:0042692	muscle cell differentiation
0.51	GO:0006323	DNA packaging
0.45	GO:0006281	DNA repair
0.43	GO:0016569	covalent chromatin modification
0.40	GO:0032986	protein-DNA complex disassembly
0.39	GO:0018393	internal peptidyl-lysine acetylation

0.54	GO:0042393	histone binding
0.50	GO:0003682	chromatin binding
0.32	GO:0016491	oxidoreductase activity

0.61	GO:0005634	nucleus
0.49	GO:0000785	chromatin
0.46	GO:0031974	membrane-enclosed lumen
0.43	GO:0043234	protein complex

0.32

GO:0016491

tr|T1G963|T1G963_HELRO
Uncharacterized protein
Search

HDAC6

0.36	Histone deacetylase

0.78	GO:0070932	histone H3 deacetylation
0.59	GO:0090042	tubulin deacetylation
0.57	GO:0070844	polyubiquitinated protein transport
0.57	GO:0070846	Hsp90 deacetylation
0.56	GO:0090035	positive regulation of chaperone-mediated protein complex assembly
0.56	GO:0006351	transcription, DNA-templated
0.55	GO:0070842	aggresome assembly
0.55	GO:0061734	parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
0.55	GO:1901300	positive regulation of hydrogen peroxide-mediated programmed cell death
0.55	GO:2001141	regulation of RNA biosynthetic process

0.79	GO:0032041	NAD-dependent histone deacetylase activity (H3-K14 specific)
0.59	GO:0042903	tubulin deacetylase activity
0.58	GO:0008270	zinc ion binding
0.55	GO:0048156	tau protein binding
0.53	GO:0051879	Hsp90 protein binding
0.53	GO:0043014	alpha-tubulin binding
0.52	GO:0031593	polyubiquitin modification-dependent protein binding
0.52	GO:0042826	histone deacetylase binding
0.52	GO:0070840	dynein complex binding
0.52	GO:0008013	beta-catenin binding

0.59	GO:0005634	nucleus
0.53	GO:0016235	aggresome
0.52	GO:0005901	caveola
0.51	GO:0043204	perikaryon
0.50	GO:0031252	cell leading edge
0.50	GO:0005881	cytoplasmic microtubule
0.50	GO:0048471	perinuclear region of cytoplasm
0.50	GO:0030286	dynein complex
0.49	GO:0030425	dendrite
0.49	GO:0030424	axon

0.79

EC:3.5.1.98

GO:0032041

tr|T1G964|T1G964_HELRO
Uncharacterized protein
Search

CDC7

0.72	Cell division control protein 7

0.63	GO:0006468	protein phosphorylation
0.56	GO:0051301	cell division
0.54	GO:0045740	positive regulation of DNA replication
0.51	GO:0033262	regulation of nuclear cell cycle DNA replication
0.51	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle
0.49	GO:0044770	cell cycle phase transition
0.48	GO:0008284	positive regulation of cell proliferation
0.45	GO:0007307	eggshell chorion gene amplification
0.45	GO:0007113	endomitotic cell cycle
0.45	GO:0000727	double-strand break repair via break-induced replication

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.33	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.51	GO:0045171	intercellular bridge
0.49	GO:0072686	mitotic spindle
0.45	GO:0005654	nucleoplasm
0.44	GO:0031431	Dbf4-dependent protein kinase complex
0.38	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.33

GO:0003755

tr|T1G965|T1G965_HELRO
Uncharacterized protein
Search

0.69	Putative calcium/calmodulin-dependent serine protein kinase/membrane-associated guanylate kinase

0.60	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity
0.55	GO:0097120	receptor localization to synapse
0.55	GO:0043113	receptor clustering
0.53	GO:0001738	morphogenesis of a polarized epithelium
0.53	GO:0046710	GDP metabolic process
0.52	GO:0016310	phosphorylation
0.51	GO:0046037	GMP metabolic process
0.51	GO:0007268	chemical synaptic transmission
0.50	GO:0007164	establishment of tissue polarity
0.49	GO:0007399	nervous system development

0.58	GO:0016301	kinase activity
0.56	GO:0035255	ionotropic glutamate receptor binding
0.50	GO:0016776	phosphotransferase activity, phosphate group as acceptor
0.49	GO:0019902	phosphatase binding
0.48	GO:0031625	ubiquitin protein ligase binding
0.47	GO:0019900	kinase binding
0.44	GO:0005154	epidermal growth factor receptor binding
0.40	GO:0030165	PDZ domain binding
0.40	GO:0008022	protein C-terminus binding
0.38	GO:0004871	signal transducer activity

0.60	GO:0008328	ionotropic glutamate receptor complex
0.53	GO:0014069	postsynaptic density
0.53	GO:0016323	basolateral plasma membrane
0.52	GO:0070160	occluding junction
0.52	GO:0043296	apical junction complex
0.51	GO:0045211	postsynaptic membrane
0.47	GO:0034703	cation channel complex
0.45	GO:0061176	type Ib terminal bouton
0.45	GO:0071212	subsynaptic reticulum
0.44	GO:0016327	apicolateral plasma membrane

0.50

EC:2.7.4

GO:0016776

tr|T1G966|T1G966_HELRO
Uncharacterized protein
Search

HSPA14

0.79	Heat shock protein 14

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.45	GO:0005829	cytosol
0.42	GO:0005840	ribosome

tr|T1G967|T1G967_HELRO
Uncharacterized protein
Search

KCTD9

0.90	Potassium channel tetramerization domain containing 9

0.78	GO:0051260	protein homooligomerization
0.51	GO:0035556	intracellular signal transduction
0.33	GO:0016567	protein ubiquitination

0.52	GO:0097602	cullin family protein binding
0.51	GO:0043621	protein self-association
0.46	GO:0042802	identical protein binding

0.40

GO:0005622

intracellular

tr|T1G968|T1G968_HELRO
Uncharacterized protein
Search

PGAP3

0.93	Post-GPI attachment to proteins factor

0.47	GO:0006505	GPI anchor metabolic process
0.39	GO:0006497	protein lipidation
0.39	GO:0006661	phosphatidylinositol biosynthetic process
0.38	GO:0009247	glycolipid biosynthetic process
0.33	GO:0030026	cellular manganese ion homeostasis

0.41	GO:0016788	hydrolase activity, acting on ester bonds
0.32	GO:0046872	metal ion binding

0.47	GO:0031227	intrinsic component of endoplasmic reticulum membrane
0.38	GO:0000139	Golgi membrane
0.33	GO:0000329	fungal-type vacuole membrane
0.30	GO:0016021	integral component of membrane

0.41

EC:3.1

GO:0016788

tr|T1G969|T1G969_HELRO
Uncharacterized protein
Search

0.60	Eukaryotic aspartyl protease

0.61	GO:0006508	proteolysis
0.47	GO:0045476	nurse cell apoptotic process
0.44	GO:0050829	defense response to Gram-negative bacterium
0.37	GO:0030163	protein catabolic process
0.35	GO:0032259	methylation
0.34	GO:0006914	autophagy
0.33	GO:0071805	potassium ion transmembrane transport
0.33	GO:0051604	protein maturation

0.70	GO:0070001	aspartic-type peptidase activity
0.65	GO:0004175	endopeptidase activity
0.35	GO:0008168	methyltransferase activity
0.34	GO:0005249	voltage-gated potassium channel activity

0.47	GO:0005764	lysosome
0.34	GO:0042470	melanosome
0.34	GO:0005576	extracellular region
0.34	GO:0008076	voltage-gated potassium channel complex

0.35

GO:0008168

tr|T1G970|T1G970_HELRO
Uncharacterized protein
Search

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.49	GO:0002074	extraocular skeletal muscle development
0.48	GO:0019101	female somatic sex determination
0.48	GO:0006309	apoptotic DNA fragmentation
0.47	GO:0001541	ovarian follicle development
0.47	GO:0060014	granulosa cell differentiation
0.47	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.46	GO:0046881	positive regulation of follicle-stimulating hormone secretion

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.48	GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process
0.45	GO:0031624	ubiquitin conjugating enzyme binding
0.45	GO:0030331	estrogen receptor binding
0.42	GO:0001012	RNA polymerase II regulatory region DNA binding
0.41	GO:0003690	double-stranded DNA binding
0.33	GO:0009055	electron transfer activity

0.61	GO:0005634	nucleus
0.45	GO:0045171	intercellular bridge
0.33	GO:0043233	organelle lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

tr|T1G971|T1G971_HELRO
Uncharacterized protein
Search

0.45	GO:0007049	cell cycle
0.44	GO:0070141	response to UV-A
0.43	GO:0044783	G1 DNA damage checkpoint
0.43	GO:0033601	positive regulation of mammary gland epithelial cell proliferation
0.43	GO:0033598	mammary gland epithelial cell proliferation
0.43	GO:0097421	liver regeneration
0.43	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity
0.42	GO:0060749	mammary gland alveolus development
0.42	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle
0.42	GO:0071157	negative regulation of cell cycle arrest

0.42	GO:0070064	proline-rich region binding
0.41	GO:0042826	histone deacetylase binding
0.41	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity
0.41	GO:0003714	transcription corepressor activity
0.41	GO:0019901	protein kinase binding
0.39	GO:0008134	transcription factor binding
0.37	GO:0004672	protein kinase activity
0.35	GO:0032403	protein complex binding
0.34	GO:0005113	patched binding
0.33	GO:0043539	protein serine/threonine kinase activator activity

0.61	GO:0005634	nucleus
0.45	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.41	GO:0017053	transcriptional repressor complex
0.41	GO:0005923	bicellular tight junction
0.38	GO:0070013	intracellular organelle lumen
0.37	GO:0015630	microtubule cytoskeleton
0.36	GO:0044446	intracellular organelle part
0.34	GO:0005737	cytoplasm
0.33	GO:0005694	chromosome
0.32	GO:0044815	DNA packaging complex

0.41

EC:2.7.1

GO:0016538

tr|T1G972|T1G972_HELRO
Uncharacterized protein
Search

0.85	Beta-2-syntrophin

0.78	GO:0050808	synapse organization
0.34	GO:0043059	regulation of forward locomotion
0.34	GO:0043058	regulation of backward locomotion
0.34	GO:0015870	acetylcholine transport
0.34	GO:0046662	regulation of oviposition
0.33	GO:0046716	muscle cell cellular homeostasis
0.33	GO:0032413	negative regulation of ion transmembrane transporter activity
0.33	GO:0045214	sarcomere organization
0.33	GO:0040013	negative regulation of locomotion
0.33	GO:0040017	positive regulation of locomotion

0.62	GO:0005198	structural molecule activity
0.34	GO:0005516	calmodulin binding
0.34	GO:0005277	acetylcholine transmembrane transporter activity
0.34	GO:0003779	actin binding
0.33	GO:0005246	calcium channel regulator activity
0.33	GO:0003723	RNA binding

0.80	GO:0016010	dystrophin-associated glycoprotein complex
0.36	GO:0045202	synapse
0.35	GO:0030054	cell junction
0.35	GO:0031982	vesicle
0.34	GO:0043230	extracellular organelle
0.34	GO:0005615	extracellular space
0.34	GO:0005874	microtubule
0.33	GO:0098805	whole membrane
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0012505	endomembrane system

tr|T1G973|T1G973_HELRO
Peptidyl-prolyl cis-trans isomerase
Search

PPIL1

0.47	Peptidyl-prolyl cis-trans isomerase

0.72	GO:0000413	protein peptidyl-prolyl isomerization
0.68	GO:0006457	protein folding
0.37	GO:0008380	RNA splicing
0.36	GO:0006397	mRNA processing

0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.48	GO:0097718	disordered domain specific binding

0.47	GO:0071013	catalytic step 2 spliceosome
0.36	GO:0070062	extracellular exosome
0.34	GO:0071011	precatalytic spliceosome
0.33	GO:0005654	nucleoplasm
0.30	GO:0044425	membrane part

0.72

GO:0003755

tr|T1G974|T1G974_HELRO
Uncharacterized protein
Search

0.72	Mitochondrial Carrier (MC) Family

0.48	GO:0055085	transmembrane transport
0.42	GO:0006839	mitochondrial transport
0.36	GO:0034659	isopropylmalate transport
0.36	GO:1900752	malonic acid transport
0.36	GO:0015729	oxaloacetate transport
0.34	GO:0072348	sulfur compound transport
0.34	GO:0006862	nucleotide transport
0.34	GO:0015698	inorganic anion transport
0.33	GO:0018193	peptidyl-amino acid modification
0.33	GO:0051182	coenzyme transport

0.37	GO:0022857	transmembrane transporter activity
0.33	GO:0005509	calcium ion binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003676	nucleic acid binding

0.43	GO:0031307	integral component of mitochondrial outer membrane
0.39	GO:0019866	organelle inner membrane

tr|T1G975|T1G975_HELRO
Uncharacterized protein
Search

tr|T1G976|T1G976_HELRO
Uncharacterized protein
Search

0.57	Fibrinogen C domain containing 1

0.41	GO:0006508	proteolysis
0.39	GO:0030199	collagen fibril organization
0.37	GO:0007186	G-protein coupled receptor signaling pathway
0.35	GO:2001141	regulation of RNA biosynthetic process
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression

0.42	GO:0008233	peptidase activity
0.39	GO:0005509	calcium ion binding
0.39	GO:0001664	G-protein coupled receptor binding
0.38	GO:0008061	chitin binding
0.38	GO:0030246	carbohydrate binding
0.35	GO:0003700	DNA binding transcription factor activity
0.34	GO:0003677	DNA binding

0.38	GO:0005578	proteinaceous extracellular matrix
0.30	GO:0031224	intrinsic component of membrane

0.42

GO:0008233

tr|T1G977|T1G977_HELRO
Uncharacterized protein
Search

ST7

0.80	Suppression of tumorigenicity

0.41	GO:0030308	negative regulation of cell growth
0.34	GO:0030198	extracellular matrix organization
0.34	GO:0045595	regulation of cell differentiation
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process

0.33

GO:0003735

structural constituent of ribosome

0.33	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

tr|T1G978|T1G978_HELRO
Histone acetyltransferase
Search

KAT8

0.55	Histone acetyltransferase

0.78	GO:0016573	histone acetylation
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0030097	hemopoiesis
0.47	GO:0010506	regulation of autophagy
0.47	GO:1902680	positive regulation of RNA biosynthetic process
0.47	GO:0030154	cell differentiation
0.46	GO:1902679	negative regulation of RNA biosynthetic process
0.43	GO:0048568	embryonic organ development

0.80	GO:0004402	histone acetyltransferase activity
0.51	GO:0140034	methylation-dependent protein binding
0.50	GO:0042393	histone binding
0.47	GO:0008134	transcription factor binding
0.46	GO:0019899	enzyme binding
0.33	GO:0046872	metal ion binding
0.32	GO:0003676	nucleic acid binding

0.85	GO:0072487	MSL complex
0.51	GO:0071339	MLL1 complex
0.49	GO:0000776	kinetochore
0.30	GO:0016020	membrane

0.80

GO:0004402

tr|T1G979|T1G979_HELRO
Uncharacterized protein
Search

OMA1

0.83	Mitochondrial metalloendopeptidase OMA1

0.73	GO:0010637	negative regulation of mitochondrial fusion
0.72	GO:0002024	diet induced thermogenesis
0.71	GO:0097009	energy homeostasis
0.66	GO:0034982	mitochondrial protein processing
0.64	GO:0006515	protein quality control for misfolded or incompletely synthesized proteins
0.58	GO:0006006	glucose metabolic process
0.55	GO:0042407	cristae formation
0.53	GO:0006629	lipid metabolic process
0.52	GO:0006950	response to stress
0.37	GO:0035694	mitochondrial protein catabolic process

0.70

GO:0004222

metalloendopeptidase activity

0.52	GO:0031966	mitochondrial membrane
0.34	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

0.70

GO:0004222

tr|T1G980|T1G980_HELRO
Uncharacterized protein
Search

0.57	GO:0006468	protein phosphorylation
0.48	GO:0035023	regulation of Rho protein signal transduction
0.47	GO:0060071	Wnt signaling pathway, planar cell polarity pathway
0.47	GO:0018212	peptidyl-tyrosine modification
0.47	GO:0060026	convergent extension
0.46	GO:0001736	establishment of planar polarity
0.45	GO:0007155	cell adhesion
0.45	GO:0006979	response to oxidative stress
0.44	GO:0098869	cellular oxidant detoxification
0.44	GO:0033334	fin morphogenesis

0.57	GO:0004672	protein kinase activity
0.50	GO:0032559	adenyl ribonucleotide binding
0.49	GO:0008144	drug binding
0.49	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.48	GO:1904929	coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway
0.45	GO:0004601	peroxidase activity
0.42	GO:0020037	heme binding
0.40	GO:0043565	sequence-specific DNA binding
0.39	GO:0005509	calcium ion binding

0.41

GO:0005887

integral component of plasma membrane

0.45	EC:1.11.1.7	GO:0004601
0.45	KEGG:R03532	GO:0004601

tr|T1G981|T1G981_HELRO
Chloride channel protein
Search

0.43	Chloride channel protein ClC-Kb

0.75	GO:1902476	chloride transmembrane transport
0.53	GO:0060689	cell differentiation involved in salivary gland development
0.49	GO:0060041	retina development in camera-type eye
0.39	GO:0034765	regulation of ion transmembrane transport
0.35	GO:0072053	renal inner medulla development
0.34	GO:0030324	lung development
0.34	GO:0007588	excretion
0.34	GO:0050878	regulation of body fluid levels

0.77	GO:0005247	voltage-gated chloride channel activity
0.34	GO:0005515	protein binding
0.33	GO:0046872	metal ion binding

0.40	GO:0034707	chloride channel complex
0.36	GO:0030054	cell junction
0.35	GO:0005886	plasma membrane
0.34	GO:0043204	perikaryon
0.34	GO:0030425	dendrite
0.34	GO:0015629	actin cytoskeleton

tr|T1G982|T1G982_HELRO
Uncharacterized protein
Search

EXOSC4

0.68	Exosome component 4

0.57	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.55	GO:0071051	polyadenylation-dependent snoRNA 3'-end processing
0.54	GO:0034475	U4 snRNA 3'-end processing
0.54	GO:0031125	rRNA 3'-end processing
0.54	GO:0071027	nuclear RNA surveillance
0.54	GO:0034427	nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'
0.51	GO:0016075	rRNA catabolic process
0.42	GO:0015031	protein transport
0.41	GO:0016078	tRNA catabolic process
0.41	GO:0043634	polyadenylation-dependent ncRNA catabolic process

0.59	GO:0004527	exonuclease activity
0.44	GO:0004540	ribonuclease activity
0.42	GO:0003727	single-stranded RNA binding
0.40	GO:0042802	identical protein binding
0.40	GO:0003690	double-stranded DNA binding
0.40	GO:0004536	deoxyribonuclease activity
0.39	GO:0009022	tRNA nucleotidyltransferase activity
0.38	GO:0046872	metal ion binding
0.34	GO:0070003	threonine-type peptidase activity
0.33	GO:0004175	endopeptidase activity

0.57	GO:0000178	exosome (RNase complex)
0.48	GO:0031981	nuclear lumen
0.45	GO:0044444	cytoplasmic part
0.44	GO:0043232	intracellular non-membrane-bounded organelle
0.38	GO:0030529	intracellular ribonucleoprotein complex
0.35	GO:0019773	proteasome core complex, alpha-subunit complex
0.30	GO:0031224	intrinsic component of membrane

0.39

EC:2.7.7.56

GO:0009022

tr|T1G983|T1G983_HELRO
Uncharacterized protein
Search

0.10	phosphatase 1 regulatory inhibitor subunit 16B

0.72	GO:0043666	regulation of phosphoprotein phosphatase activity
0.59	GO:1902309	negative regulation of peptidyl-serine dephosphorylation
0.58	GO:1903589	positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis
0.56	GO:0061028	establishment of endothelial barrier
0.55	GO:0035307	positive regulation of protein dephosphorylation
0.55	GO:0014066	regulation of phosphatidylinositol 3-kinase signaling
0.47	GO:0007476	imaginal disc-derived wing morphogenesis
0.38	GO:0051489	regulation of filopodium assembly
0.35	GO:0006470	protein dephosphorylation
0.32	GO:0009058	biosynthetic process

0.73	GO:0019888	protein phosphatase regulator activity
0.47	GO:0008157	protein phosphatase 1 binding
0.36	GO:0004721	phosphoprotein phosphatase activity
0.35	GO:0004622	lysophospholipase activity
0.33	GO:0030170	pyridoxal phosphate binding

0.52	GO:0016607	nuclear speck
0.52	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0042995	cell projection
0.42	GO:0005886	plasma membrane
0.34	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.36

GO:0004721

tr|T1G984|T1G984_HELRO
Uncharacterized protein
Search

FZD9

0.88	Frizzled class receptor 9

0.71	GO:0016055	Wnt signaling pathway
0.66	GO:0007275	multicellular organism development
0.55	GO:1904394	negative regulation of skeletal muscle acetylcholine-gated channel clustering
0.54	GO:1990523	bone regeneration
0.54	GO:0061351	neural precursor cell proliferation
0.53	GO:0060828	regulation of canonical Wnt signaling pathway
0.52	GO:0071157	negative regulation of cell cycle arrest
0.52	GO:2000179	positive regulation of neural precursor cell proliferation
0.52	GO:0030501	positive regulation of bone mineralization
0.51	GO:0001775	cell activation

0.70	GO:0004888	transmembrane signaling receptor activity
0.58	GO:0017147	Wnt-protein binding
0.47	GO:0042803	protein homodimerization activity
0.47	GO:0046982	protein heterodimerization activity
0.41	GO:0031625	ubiquitin protein ligase binding
0.32	GO:0003677	DNA binding

0.52	GO:0031527	filopodium membrane
0.49	GO:0048471	perinuclear region of cytoplasm
0.48	GO:0009986	cell surface
0.43	GO:0016327	apicolateral plasma membrane
0.42	GO:0045177	apical part of cell
0.35	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0005794	Golgi apparatus
0.35	GO:0031090	organelle membrane
0.34	GO:0005740	mitochondrial envelope
0.34	GO:0044433	cytoplasmic vesicle part

tr|T1G985|T1G985_HELRO
Uncharacterized protein
Search

0.10	CREB-binding protein (Fragment)

0.78	GO:0016573	histone acetylation
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.47	GO:0018076	N-terminal peptidyl-lysine acetylation
0.45	GO:0031648	protein destabilization
0.44	GO:0034644	cellular response to UV
0.43	GO:1902680	positive regulation of RNA biosynthetic process
0.41	GO:0048523	negative regulation of cellular process
0.41	GO:0010558	negative regulation of macromolecule biosynthetic process

0.80	GO:0004402	histone acetyltransferase activity
0.76	GO:0003712	transcription cofactor activity
0.63	GO:0008270	zinc ion binding
0.46	GO:0043426	MRF binding
0.45	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.44	GO:0002039	p53 binding
0.44	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.44	GO:0001085	RNA polymerase II transcription factor binding
0.43	GO:0000987	proximal promoter sequence-specific DNA binding
0.42	GO:0003682	chromatin binding

0.72	GO:0000123	histone acetyltransferase complex
0.43	GO:0016604	nuclear body
0.42	GO:0000790	nuclear chromatin
0.39	GO:0005700	polytene chromosome
0.38	GO:0035097	histone methyltransferase complex
0.38	GO:0098793	presynapse
0.35	GO:0005737	cytoplasm
0.35	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.80

GO:0004402

tr|T1G986|T1G986_HELRO
Uncharacterized protein
Search

0.63	F-box only protein 11

0.73	GO:0016567	protein ubiquitination
0.44	GO:0070923	siRNA loading onto RISC involved in chromatin silencing by small RNA
0.41	GO:0060966	regulation of gene silencing by RNA
0.40	GO:0035246	peptidyl-arginine N-methylation
0.40	GO:0007605	sensory perception of sound
0.35	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
0.33	GO:0043687	post-translational protein modification

0.63	GO:0008270	zinc ion binding
0.40	GO:0016274	protein-arginine N-methyltransferase activity
0.39	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0005515	protein binding

0.76	GO:0000151	ubiquitin ligase complex
0.40	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0005730	nucleolus
0.37	GO:0005829	cytosol
0.33	GO:0005694	chromosome
0.30	GO:0016020	membrane

0.40	EC:2.1.1	GO:0016274
0.39	KEGG:R03876	GO:0004842

tr|T1G987|T1G987_HELRO
Uncharacterized protein
Search

DNAJA1

0.79	Type I heat shock protein 40

0.73	GO:0009408	response to heat
0.69	GO:0006457	protein folding
0.52	GO:1905259	negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway
0.52	GO:0043508	negative regulation of JUN kinase activity
0.51	GO:1903748	negative regulation of establishment of protein localization to mitochondrion
0.49	GO:0031397	negative regulation of protein ubiquitination
0.48	GO:0032781	positive regulation of ATPase activity
0.47	GO:0043065	positive regulation of apoptotic process
0.47	GO:0070585	protein localization to mitochondrion
0.47	GO:0051223	regulation of protein transport

0.77	GO:0031072	heat shock protein binding
0.71	GO:0051082	unfolded protein binding
0.53	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0046872	metal ion binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0055131	C3HC4-type RING finger domain binding
0.51	GO:0030957	Tat protein binding
0.50	GO:0050750	low-density lipoprotein particle receptor binding
0.49	GO:0001671	ATPase activator activity

0.46	GO:0005829	cytosol
0.46	GO:0000151	ubiquitin ligase complex
0.44	GO:0015630	microtubule cytoskeleton
0.39	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0005783	endoplasmic reticulum
0.36	GO:0005634	nucleus
0.36	GO:0005739	mitochondrion
0.36	GO:0070062	extracellular exosome
0.34	GO:0098562	cytoplasmic side of membrane
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network

tr|T1G988|T1G988_HELRO
Uncharacterized protein
Search

tr|T1G989|T1G989_HELRO
Uncharacterized protein
Search

ABCC1

0.52	Canalicular multispecific organic anion transporter 1

0.56	GO:0015711	organic anion transport
0.55	GO:0055085	transmembrane transport
0.40	GO:0010038	response to metal ion
0.38	GO:0032870	cellular response to hormone stimulus
0.38	GO:0061687	detoxification of inorganic compound
0.38	GO:0042144	vacuole fusion, non-autophagic
0.37	GO:0006749	glutathione metabolic process
0.36	GO:0015849	organic acid transport
0.36	GO:0045454	cell redox homeostasis
0.35	GO:0006950	response to stress

0.66	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.58	GO:0008514	organic anion transmembrane transporter activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0005342	organic acid transmembrane transporter activity
0.35	GO:0015318	inorganic molecular entity transmembrane transporter activity

0.55	GO:0005887	integral component of plasma membrane
0.44	GO:0046581	intercellular canaliculus
0.42	GO:0016324	apical plasma membrane
0.40	GO:0009986	cell surface
0.37	GO:0000329	fungal-type vacuole membrane

tr|T1G990|T1G990_HELRO
Uncharacterized protein
Search

STX12

0.84	Syntaxin-7

0.69	GO:0016192	vesicle-mediated transport
0.68	GO:0006886	intracellular protein transport
0.68	GO:0061025	membrane fusion
0.56	GO:1902685	positive regulation of receptor localization to synapse
0.54	GO:0001916	positive regulation of T cell mediated cytotoxicity
0.52	GO:1903076	regulation of protein localization to plasma membrane
0.49	GO:0051640	organelle localization
0.47	GO:0070925	organelle assembly
0.45	GO:0065009	regulation of molecular function
0.43	GO:0048284	organelle fusion

0.80	GO:0005484	SNAP receptor activity
0.54	GO:0019869	chloride channel inhibitor activity
0.52	GO:0000149	SNARE binding
0.34	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.34	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
0.33	GO:0032403	protein complex binding
0.33	GO:0005507	copper ion binding
0.32	GO:0003676	nucleic acid binding

0.54	GO:0070820	tertiary granule
0.54	GO:0005766	primary lysosome
0.53	GO:0001772	immunological synapse
0.51	GO:0055037	recycling endosome
0.50	GO:0030139	endocytic vesicle
0.50	GO:0005769	early endosome
0.50	GO:0005770	late endosome
0.50	GO:0048471	perinuclear region of cytoplasm
0.44	GO:0031201	SNARE complex
0.37	GO:0010008	endosome membrane

0.34

EC:1.14.17

GO:0016715

tr|T1G991|T1G991_HELRO
Uncharacterized protein
Search

GALNS

0.27	N-acetylgalactosamine-6-sulfatase

0.34	GO:0042340	keratan sulfate catabolic process
0.34	GO:0009116	nucleoside metabolic process
0.34	GO:0043312	neutrophil degranulation
0.33	GO:0019083	viral transcription
0.33	GO:0001172	transcription, RNA-templated

0.75	GO:0008484	sulfuric ester hydrolase activity
0.33	GO:0046872	metal ion binding
0.33	GO:0003723	RNA binding
0.33	GO:0003968	RNA-directed 5'-3' RNA polymerase activity

0.37	GO:0005764	lysosome
0.35	GO:0005615	extracellular space
0.35	GO:1903561	extracellular vesicle
0.34	GO:0034774	secretory granule lumen
0.34	GO:0005775	vacuolar lumen
0.33	GO:0005783	endoplasmic reticulum

0.75

EC:3.1.6

GO:0008484

tr|T1G992|T1G992_HELRO
Uncharacterized protein
Search

tr|T1G993|T1G993_HELRO
Uncharacterized protein
Search

DUS1L

0.43	Trna dihydrouridine synthase

0.77	GO:0002943	tRNA dihydrouridine synthesis
0.53	GO:0055114	oxidation-reduction process
0.33	GO:0043043	peptide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0009059	macromolecule biosynthetic process

0.77	GO:0017150	tRNA dihydrouridine synthase activity
0.66	GO:0050660	flavin adenine dinucleotide binding
0.34	GO:0047465	N-acylglucosamine-6-phosphate 2-epimerase activity
0.34	GO:0019707	protein-cysteine S-acyltransferase activity
0.34	GO:0016409	palmitoyltransferase activity
0.34	GO:0031177	phosphopantetheine binding
0.33	GO:0003735	structural constituent of ribosome
0.33	GO:0016829	lyase activity
0.33	GO:0016788	hydrolase activity, acting on ester bonds

0.33	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.34

EC:5.1.3.9

GO:0047465

tr|T1G994|T1G994_HELRO
Autophagy-related protein 9
Search

0.75	Autophagy-related protein 9

0.77	GO:0006914	autophagy
0.65	GO:0015031	protein transport
0.44	GO:0007033	vacuole organization
0.42	GO:0061726	mitochondrion disassembly
0.42	GO:0070925	organelle assembly
0.38	GO:0034613	cellular protein localization
0.35	GO:0031667	response to nutrient levels
0.35	GO:0035096	larval midgut cell programmed cell death
0.34	GO:0046330	positive regulation of JNK cascade
0.34	GO:0005980	glycogen catabolic process

0.76	GO:0030659	cytoplasmic vesicle membrane
0.71	GO:0005794	Golgi apparatus
0.45	GO:0000407	phagophore assembly site
0.42	GO:0005776	autophagosome
0.41	GO:0055037	recycling endosome
0.41	GO:0005770	late endosome
0.38	GO:0031984	organelle subcompartment
0.33	GO:0030054	cell junction
0.30	GO:0016021	integral component of membrane

tr|T1G995|T1G995_HELRO
Serine hydroxymethyltransferase
Search

SHMT1

0.47	Serine hydroxymethyltransferase

0.78	GO:0019264	glycine biosynthetic process from serine
0.75	GO:0035999	tetrahydrofolate interconversion
0.56	GO:1904481	response to tetrahydrofolate
0.55	GO:0006565	L-serine catabolic process
0.54	GO:0032259	methylation
0.53	GO:0051289	protein homotetramerization
0.50	GO:0071229	cellular response to acid chemical
0.50	GO:0071417	cellular response to organonitrogen compound
0.49	GO:0046655	folic acid metabolic process
0.49	GO:0071407	cellular response to organic cyclic compound

0.78	GO:0004372	glycine hydroxymethyltransferase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.55	GO:0070905	serine binding
0.55	GO:0008168	methyltransferase activity
0.53	GO:0000900	translation repressor activity, nucleic acid binding
0.50	GO:0048027	mRNA 5'-UTR binding
0.48	GO:0042803	protein homodimerization activity
0.37	GO:0008732	L-allo-threonine aldolase activity
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding

0.49	GO:0005829	cytosol
0.45	GO:0005634	nucleus
0.40	GO:0005739	mitochondrion
0.36	GO:0070062	extracellular exosome

0.78

EC:2.1.2.1

GO:0004372

tr|T1G996|T1G996_HELRO
Uncharacterized protein
Search

tr|T1G997|T1G997_HELRO
Uncharacterized protein
Search

GLDC

0.71	Glycine dehydrogenase (decarboxylating), mitochondrial

0.75	GO:0006546	glycine catabolic process
0.52	GO:0055114	oxidation-reduction process
0.42	GO:1990830	cellular response to leukemia inhibitory factor
0.38	GO:0036255	response to methylamine
0.38	GO:1903442	response to lipoic acid
0.36	GO:0006730	one-carbon metabolic process

0.78	GO:0016642	oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor
0.50	GO:0016829	lyase activity
0.38	GO:0070280	pyridoxal binding
0.36	GO:0016594	glycine binding
0.36	GO:0047960	glycine dehydrogenase activity
0.35	GO:0046983	protein dimerization activity
0.35	GO:0042802	identical protein binding
0.35	GO:0019899	enzyme binding
0.34	GO:0030170	pyridoxal phosphate binding

0.60	GO:0005739	mitochondrion
0.38	GO:0005634	nucleus
0.37	GO:0005886	plasma membrane
0.35	GO:0005960	glycine cleavage complex
0.30	GO:0016021	integral component of membrane

0.78

EC:1.4.4

GO:0016642

tr|T1G998|T1G998_HELRO
Uncharacterized protein
Search

CASP7

0.88	'Caspase 7, apoptosis-related cysteine peptidase'

0.61	GO:0006508	proteolysis
0.54	GO:0097194	execution phase of apoptosis
0.53	GO:0051402	neuron apoptotic process
0.50	GO:0009411	response to UV
0.50	GO:0007507	heart development
0.47	GO:0051604	protein maturation
0.42	GO:0072734	cellular response to staurosporine
0.40	GO:0043065	positive regulation of apoptotic process
0.40	GO:0030216	keratinocyte differentiation
0.39	GO:0030218	erythrocyte differentiation

0.75	GO:0004197	cysteine-type endopeptidase activity
0.46	GO:0070001	aspartic-type peptidase activity
0.38	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity
0.34	GO:0005515	protein binding

0.38	GO:0005829	cytosol
0.36	GO:0005634	nucleus
0.33	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0043233	organelle lumen
0.33	GO:0031966	mitochondrial membrane
0.30	GO:0031224	intrinsic component of membrane

0.75

EC:3.4.22

GO:0004197

tr|T1G999|T1G999_HELRO
Uncharacterized protein
Search

S36A4

0.39	Proton-coupled amino acid transporter

0.55	GO:0032974	amino acid transmembrane export from vacuole
0.55	GO:1990961	drug transmembrane export
0.54	GO:0015817	histidine transport
0.54	GO:1903400	L-arginine transmembrane transport
0.54	GO:0089709	L-histidine transmembrane transport
0.54	GO:1903401	L-lysine transmembrane transport
0.37	GO:0006868	glutamine transport
0.37	GO:0015828	tyrosine transport
0.36	GO:0015803	branched-chain amino acid transport
0.32	GO:0009058	biosynthetic process

0.54	GO:0061459	L-arginine transmembrane transporter activity
0.54	GO:0005290	L-histidine transmembrane transporter activity
0.54	GO:0015189	L-lysine transmembrane transporter activity
0.37	GO:0015188	L-isoleucine transmembrane transporter activity
0.37	GO:0015186	L-glutamine transmembrane transporter activity
0.37	GO:0005302	L-tyrosine transmembrane transporter activity
0.33	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups

0.51	GO:0000329	fungal-type vacuole membrane
0.37	GO:1990816	vacuole-mitochondrion membrane contact site
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:2.3.1

GO:0016747

tr|T1G9A0|T1G9A0_HELRO
Uncharacterized protein
Search

PIK3CB

0.97	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta

0.81	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process
0.79	GO:0048015	phosphatidylinositol-mediated signaling
0.73	GO:0046854	phosphatidylinositol phosphorylation
0.58	GO:0033031	positive regulation of neutrophil apoptotic process
0.54	GO:0001952	regulation of cell-matrix adhesion
0.50	GO:0030168	platelet activation
0.49	GO:0040016	embryonic cleavage
0.48	GO:0010628	positive regulation of gene expression
0.48	GO:0060055	angiogenesis involved in wound healing
0.48	GO:0001935	endothelial cell proliferation

0.83	GO:0035004	phosphatidylinositol 3-kinase activity
0.81	GO:0052742	phosphatidylinositol kinase activity
0.49	GO:0052813	phosphatidylinositol bisphosphate kinase activity
0.48	GO:0043560	insulin receptor substrate binding
0.45	GO:0016307	phosphatidylinositol phosphate kinase activity
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0097367	carbohydrate derivative binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0043565	sequence-specific DNA binding

0.52	GO:0030496	midbody
0.48	GO:0005730	nucleolus
0.45	GO:0005942	phosphatidylinositol 3-kinase complex
0.38	GO:0005886	plasma membrane
0.36	GO:0005737	cytoplasm
0.35	GO:0005903	brush border
0.34	GO:0120038	plasma membrane bounded cell projection part
0.30	GO:0016021	integral component of membrane

0.83

EC:2.7.1

GO:0035004

tr|T1G9A1|T1G9A1_HELRO
Uncharacterized protein
Search

SKIV2L2

0.92	Superkiller viralicidic activity 2-like protein 2

0.72	GO:0006401	RNA catabolic process
0.53	GO:0000460	maturation of 5.8S rRNA
0.40	GO:0051607	defense response to virus
0.40	GO:0031101	fin regeneration
0.39	GO:0051781	positive regulation of cell division
0.36	GO:0008380	RNA splicing
0.35	GO:0006397	mRNA processing

0.76	GO:0003724	RNA helicase activity
0.59	GO:0003723	RNA binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0008186	RNA-dependent ATPase activity
0.43	GO:0070035	purine NTP-dependent helicase activity
0.33	GO:0005515	protein binding

0.51	GO:0071013	catalytic step 2 spliceosome
0.50	GO:0000178	exosome (RNase complex)
0.35	GO:0005730	nucleolus
0.35	GO:0005654	nucleoplasm

0.76

EC:2.7.7

GO:0003724

tr|T1G9A2|T1G9A2_HELRO
Uncharacterized protein
Search

0.49	Digestive cysteine protease

0.61	GO:0006508	proteolysis
0.40	GO:0044257	cellular protein catabolic process
0.34	GO:0007275	multicellular organism development
0.34	GO:0007586	digestion
0.33	GO:0030154	cell differentiation

0.72	GO:0008234	cysteine-type peptidase activity
0.40	GO:0004175	endopeptidase activity
0.34	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
0.33	GO:0035091	phosphatidylinositol binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.44	GO:0005764	lysosome
0.41	GO:0005615	extracellular space
0.39	GO:0045169	fusome
0.30	GO:0031224	intrinsic component of membrane

0.72

GO:0008234

tr|T1G9A3|T1G9A3_HELRO
Uncharacterized protein
Search

0.95	Putative catalytic step 2 spliceosome

0.30

GO:0044425

membrane part

tr|T1G9A4|T1G9A4_HELRO
Uncharacterized protein
Search

0.79	GO:0030522	intracellular receptor signaling pathway
0.79	GO:0043401	steroid hormone mediated signaling pathway
0.59	GO:0071376	cellular response to corticotropin-releasing hormone stimulus
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0045444	fat cell differentiation
0.52	GO:0043065	positive regulation of apoptotic process
0.52	GO:0043066	negative regulation of apoptotic process

0.82	GO:0004879	nuclear receptor activity
0.80	GO:0003707	steroid hormone receptor activity
0.64	GO:0043565	sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.54	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.48	GO:0042803	protein homodimerization activity
0.48	GO:0046982	protein heterodimerization activity
0.45	GO:0001223	transcription coactivator binding
0.45	GO:0035035	histone acetyltransferase binding
0.43	GO:0001047	core promoter binding

0.61	GO:0005634	nucleus
0.50	GO:0005667	transcription factor complex
0.46	GO:0005829	cytosol
0.46	GO:0012505	endomembrane system
0.45	GO:0042629	mast cell granule
0.43	GO:0031967	organelle envelope
0.43	GO:0031090	organelle membrane
0.33	GO:0070013	intracellular organelle lumen

tr|T1G9A5|T1G9A5_HELRO
Uncharacterized protein
Search

DDX47

0.49	Apolipoprotein-L domain-containing protein 1

0.54	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors
0.49	GO:0006364	rRNA processing
0.48	GO:0008380	RNA splicing
0.46	GO:0010501	RNA secondary structure unwinding
0.38	GO:0042274	ribosomal small subunit biogenesis
0.36	GO:0006397	mRNA processing
0.33	GO:0035556	intracellular signal transduction
0.33	GO:0005975	carbohydrate metabolic process

0.66	GO:0004386	helicase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0003676	nucleic acid binding
0.47	GO:0008186	RNA-dependent ATPase activity
0.41	GO:0140098	catalytic activity, acting on RNA
0.33	GO:0030246	carbohydrate binding
0.33	GO:0005515	protein binding
0.33	GO:0016853	isomerase activity

0.50	GO:0005730	nucleolus
0.36	GO:0005737	cytoplasm
0.33	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

0.33

EC:5

GO:0016853

tr|T1G9A6|T1G9A6_HELRO
Uncharacterized protein
Search

FLII

0.91	Flightless I

0.84	GO:0051014	actin filament severing
0.74	GO:0030036	actin cytoskeleton organization
0.47	GO:0048856	anatomical structure development
0.44	GO:0032501	multicellular organismal process
0.42	GO:0097435	supramolecular fiber organization
0.41	GO:0030154	cell differentiation
0.41	GO:0070925	organelle assembly
0.33	GO:0006351	transcription, DNA-templated
0.33	GO:0006470	protein dephosphorylation
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.78	GO:0051015	actin filament binding
0.33	GO:0004721	phosphoprotein phosphatase activity

0.49	GO:0005903	brush border
0.46	GO:0005815	microtubule organizing center
0.44	GO:0005654	nucleoplasm
0.44	GO:0005829	cytosol
0.36	GO:0005925	focal adhesion
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0004721

tr|T1G9A7|T1G9A7_HELRO
Uncharacterized protein
Search

OGFOD1

0.78	2-oxoglutarate and iron dependent oxygenase domain containing 1

0.53	GO:0055114	oxidation-reduction process
0.48	GO:0019511	peptidyl-proline hydroxylation
0.47	GO:0034063	stress granule assembly
0.47	GO:0006449	regulation of translational termination
0.45	GO:0008283	cell proliferation

0.79	GO:0016706	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
0.79	GO:0031418	L-ascorbic acid binding
0.63	GO:0005506	iron ion binding
0.39	GO:0140096	catalytic activity, acting on a protein

0.45	GO:0010494	cytoplasmic stress granule
0.41	GO:0005829	cytosol
0.39	GO:0005634	nucleus

0.79

EC:1.14.11

GO:0016706

tr|T1G9A8|T1G9A8_HELRO
Uncharacterized protein
Search

0.56	Non-muscle actin II

0.53	GO:0030554	adenyl nucleotide binding
0.52	GO:0097367	carbohydrate derivative binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0008146	sulfotransferase activity

0.43	GO:0005856	cytoskeleton
0.37	GO:0097433	dense body
0.36	GO:0005925	focal adhesion
0.33	GO:0005886	plasma membrane
0.33	GO:0005634	nucleus
0.33	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:2.8.2

GO:0008146

tr|T1G9A9|T1G9A9_HELRO
Uncharacterized protein
Search

0.76	Guanine nucleotide-binding protein subunit alpha

0.75	GO:0007264	small GTPase mediated signal transduction
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.46	GO:0048598	embryonic morphogenesis
0.44	GO:0010762	regulation of fibroblast migration
0.44	GO:0030154	cell differentiation
0.43	GO:0043149	stress fiber assembly
0.43	GO:0035108	limb morphogenesis
0.43	GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process
0.43	GO:0060973	cell migration involved in heart development
0.43	GO:0090504	epiboly

0.81	GO:0031683	G-protein beta/gamma-subunit complex binding
0.78	GO:0001664	G-protein coupled receptor binding
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.64	GO:0004871	signal transducer activity
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0046872	metal ion binding

0.45	GO:0031526	brush border membrane
0.44	GO:1905360	GTPase complex
0.44	GO:0005622	intracellular
0.43	GO:0019897	extrinsic component of plasma membrane
0.43	GO:0009898	cytoplasmic side of plasma membrane
0.40	GO:0098797	plasma membrane protein complex
0.35	GO:0043227	membrane-bounded organelle

tr|T1G9B0|T1G9B0_HELRO
Citrate synthase
Search

0.46	Citrate synthase, mitochondrial

0.70	GO:0006101	citrate metabolic process
0.63	GO:0009060	aerobic respiration
0.36	GO:0005975	carbohydrate metabolic process
0.34	GO:0007610	behavior

0.80

GO:0004108

citrate (Si)-synthase activity

0.39

GO:0005759

mitochondrial matrix

0.80

EC:2.3.3.1

GO:0004108

tr|T1G9B1|T1G9B1_HELRO
Uncharacterized protein
Search

0.48	GO:0043044	ATP-dependent chromatin remodeling
0.39	GO:1903355	negative regulation of distal tip cell migration
0.39	GO:0098507	polynucleotide 5' dephosphorylation
0.39	GO:0036211	protein modification process
0.38	GO:0031323	regulation of cellular metabolic process
0.38	GO:0051171	regulation of nitrogen compound metabolic process
0.38	GO:0060255	regulation of macromolecule metabolic process
0.38	GO:0080090	regulation of primary metabolic process
0.38	GO:0040035	hermaphrodite genitalia development
0.38	GO:0043053	dauer entry

0.45	GO:0003676	nucleic acid binding
0.42	GO:0008270	zinc ion binding
0.40	GO:0030554	adenyl nucleotide binding
0.40	GO:0097367	carbohydrate derivative binding
0.40	GO:0008144	drug binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0004651	polynucleotide 5'-phosphatase activity
0.39	GO:0140110	transcription regulator activity
0.36	GO:0140096	catalytic activity, acting on a protein
0.36	GO:0016772	transferase activity, transferring phosphorus-containing groups

0.42	GO:0005634	nucleus
0.35	GO:0070013	intracellular organelle lumen
0.35	GO:0031248	protein acetyltransferase complex
0.35	GO:1905368	peptidase complex
0.34	GO:0043234	protein complex
0.34	GO:0044446	intracellular organelle part
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.39

EC:3.1.3.33

GO:0004651

tr|T1G9B2|T1G9B2_HELRO
DNA helicase
Search

MCM7

0.43	DNA helicase

0.72	GO:0006270	DNA replication initiation
0.67	GO:0032392	DNA geometric change
0.49	GO:0008283	cell proliferation
0.48	GO:0071466	cellular response to xenobiotic stimulus
0.46	GO:0042325	regulation of phosphorylation
0.43	GO:0006974	cellular response to DNA damage stimulus
0.38	GO:0071364	cellular response to epidermal growth factor stimulus
0.36	GO:0042493	response to drug
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.68	GO:0003678	DNA helicase activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0003677	DNA binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0070035	purine NTP-dependent helicase activity
0.45	GO:0008094	DNA-dependent ATPase activity

0.76	GO:0042555	MCM complex
0.59	GO:0005634	nucleus
0.45	GO:0005829	cytosol
0.44	GO:0031974	membrane-enclosed lumen
0.40	GO:0044446	intracellular organelle part
0.33	GO:0005694	chromosome
0.30	GO:0031224	intrinsic component of membrane

tr|T1G9B3|T1G9B3_HELRO
Uncharacterized protein
Search

DDAH1

0.69	Ng dimethylarginine dimethylaminohydrolase

0.83	GO:0000052	citrulline metabolic process
0.80	GO:0045429	positive regulation of nitric oxide biosynthetic process
0.72	GO:0006527	arginine catabolic process
0.57	GO:0043116	negative regulation of vascular permeability
0.57	GO:1900038	negative regulation of cellular response to hypoxia
0.54	GO:0003073	regulation of systemic arterial blood pressure
0.52	GO:0008285	negative regulation of cell proliferation
0.40	GO:0045766	positive regulation of angiogenesis
0.38	GO:0017014	protein nitrosylation
0.37	GO:0006809	nitric oxide biosynthetic process

0.82	GO:0016403	dimethylargininase activity
0.39	GO:0016597	amino acid binding
0.35	GO:0046872	metal ion binding

0.44	GO:0005739	mitochondrion
0.37	GO:0070062	extracellular exosome
0.34	GO:0005829	cytosol

0.82

EC:3.5.3.18

GO:0016403

tr|T1G9B4|T1G9B4_HELRO
Phospholipid-transporting ATPase
Search

ATP9B

0.56	Phospholipid-transporting ATPase

0.80	GO:0045332	phospholipid translocation
0.44	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.41	GO:0006897	endocytosis
0.34	GO:0006434	seryl-tRNA aminoacylation
0.34	GO:0032218	riboflavin transport

0.81	GO:0004012	phospholipid-translocating ATPase activity
0.64	GO:0000287	magnesium ion binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0004828	serine-tRNA ligase activity
0.34	GO:0032217	riboflavin transmembrane transporter activity

0.80	GO:0005802	trans-Golgi network
0.54	GO:0005768	endosome
0.48	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0005886	plasma membrane
0.33	GO:0044433	cytoplasmic vesicle part
0.33	GO:0098805	whole membrane
0.33	GO:0098588	bounding membrane of organelle
0.30	GO:0031224	intrinsic component of membrane

0.81

EC:3.6.3.1

GO:0004012

tr|T1G9B5|T1G9B5_HELRO
Uncharacterized protein
Search

PMPCB

0.74	Mitochondrial ubiquinol-cytochrome-c reductase complex core protein i

0.73	GO:0006627	protein processing involved in protein targeting to mitochondrion
0.45	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c
0.40	GO:0009060	aerobic respiration
0.35	GO:0008272	sulfate transport
0.35	GO:0098661	inorganic anion transmembrane transport
0.35	GO:0007166	cell surface receptor signaling pathway
0.35	GO:0007186	G-protein coupled receptor signaling pathway
0.35	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.34	GO:0006851	mitochondrial calcium ion transmembrane transport
0.34	GO:0031047	gene silencing by RNA

0.64	GO:0004222	metalloendopeptidase activity
0.54	GO:0046872	metal ion binding
0.40	GO:0031625	ubiquitin protein ligase binding
0.36	GO:0008271	secondary active sulfate transmembrane transporter activity
0.35	GO:0004930	G-protein coupled receptor activity
0.34	GO:0016681	oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor
0.33	GO:0003684	damaged DNA binding
0.33	GO:0009055	electron transfer activity

0.75	GO:0017087	mitochondrial processing peptidase complex
0.46	GO:0005750	mitochondrial respiratory chain complex III
0.40	GO:0043209	myelin sheath
0.38	GO:0005829	cytosol
0.33	GO:0005886	plasma membrane
0.32	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.64

GO:0004222

tr|T1G9B6|T1G9B6_HELRO
Uncharacterized protein
Search

0.82	Prohormone and neuropeptide processing protease

0.61	GO:0006508	proteolysis
0.48	GO:0030537	larval behavior
0.47	GO:0035187	hatching behavior
0.46	GO:0042445	hormone metabolic process
0.45	GO:0051604	protein maturation
0.44	GO:1901142	insulin metabolic process
0.44	GO:0002165	instar larval or pupal development
0.44	GO:0007626	locomotory behavior
0.44	GO:0033500	carbohydrate homeostasis
0.42	GO:1905850	positive regulation of forward locomotion

0.69	GO:0004252	serine-type endopeptidase activity
0.41	GO:0098770	FBXO family protein binding
0.34	GO:0032403	protein complex binding
0.33	GO:0004222	metalloendopeptidase activity

0.42	GO:0005576	extracellular region
0.39	GO:0043005	neuron projection
0.35	GO:0005634	nucleus
0.35	GO:0034774	secretory granule lumen
0.34	GO:0043204	perikaryon
0.34	GO:0030133	transport vesicle
0.34	GO:0120038	plasma membrane bounded cell projection part
0.30	GO:0031224	intrinsic component of membrane

0.69

EC:3.4.21

GO:0004252

tr|T1G9B7|T1G9B7_HELRO
Uncharacterized protein
Search

0.59	Monoacylglycerol lipase

0.47	GO:0009966	regulation of signal transduction
0.44	GO:0006629	lipid metabolic process

0.67	GO:0047372	acylglycerol lipase activity
0.42	GO:0004622	lysophospholipase activity

0.47	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.67

EC:3.1.1.23

GO:0047372

tr|T1G9B8|T1G9B8_HELRO
Uncharacterized protein
Search

ADAM12

0.57	Disintegrin and metalloproteinase domain-containing protein 12

0.66	GO:0007229	integrin-mediated signaling pathway
0.61	GO:0006508	proteolysis
0.34	GO:0007507	heart development
0.32	GO:0016310	phosphorylation
0.32	GO:0007064	mitotic sister chromatid cohesion

0.70	GO:0004222	metalloendopeptidase activity
0.54	GO:0046872	metal ion binding
0.49	GO:0017124	SH3 domain binding
0.33	GO:0016301	kinase activity
0.32	GO:0003682	chromatin binding
0.32	GO:0046982	protein heterodimerization activity
0.31	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.46	GO:0005794	Golgi apparatus
0.32	GO:0008278	cohesin complex
0.32	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.70

GO:0004222

tr|T1G9B9|T1G9B9_HELRO
Uncharacterized protein
Search

tr|T1G9C0|T1G9C0_HELRO
Uncharacterized protein
Search

0.36	WD repeat-containing protein 5B

0.56	GO:0000132	establishment of mitotic spindle orientation
0.48	GO:0051301	cell division
0.42	GO:0006468	protein phosphorylation
0.37	GO:0071248	cellular response to metal ion
0.36	GO:0007281	germ cell development
0.36	GO:0008090	retrograde axonal transport
0.36	GO:0016567	protein ubiquitination
0.36	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle
0.36	GO:0051012	microtubule sliding
0.35	GO:0070143	mitochondrial alanyl-tRNA aminoacylation

0.56	GO:0070840	dynein complex binding
0.42	GO:0004672	protein kinase activity
0.42	GO:0005509	calcium ion binding
0.40	GO:0030554	adenyl nucleotide binding
0.40	GO:0097367	carbohydrate derivative binding
0.39	GO:0043168	anion binding
0.39	GO:0008144	drug binding
0.35	GO:0000906	6,7-dimethyl-8-ribityllumazine synthase activity
0.35	GO:0043565	sequence-specific DNA binding
0.35	GO:0004435	phosphatidylinositol phospholipase C activity

0.52	GO:0005875	microtubule associated complex
0.52	GO:0005815	microtubule organizing center
0.52	GO:0005874	microtubule
0.40	GO:0005737	cytoplasm
0.36	GO:0120038	plasma membrane bounded cell projection part
0.36	GO:0043224	nuclear SCF ubiquitin ligase complex
0.35	GO:0009349	riboflavin synthase complex
0.35	GO:0030424	axon
0.35	GO:0000776	kinetochore
0.34	GO:0032040	small-subunit processome

0.35	EC:5.4	GO:0000906
0.35	KEGG:R03435	GO:0004435

tr|T1G9C1|T1G9C1_HELRO
Uncharacterized protein
Search

DNAH10

0.81	Flagellar inner arm dynein 1 heavy chain alpha

0.74	GO:0007018	microtubule-based movement
0.36	GO:0007010	cytoskeleton organization
0.36	GO:0051261	protein depolymerization
0.36	GO:0097435	supramolecular fiber organization
0.35	GO:0060285	cilium-dependent cell motility
0.35	GO:0060271	cilium assembly
0.35	GO:0030029	actin filament-based process
0.34	GO:0099518	vesicle cytoskeletal trafficking
0.34	GO:0043623	cellular protein complex assembly
0.33	GO:0016310	phosphorylation

0.75	GO:0003777	microtubule motor activity
0.59	GO:0016887	ATPase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0045503	dynein light chain binding
0.53	GO:0051959	dynein light intermediate chain binding
0.53	GO:0045505	dynein intermediate chain binding
0.36	GO:0008092	cytoskeletal protein binding
0.35	GO:0003951	NAD+ kinase activity

0.77	GO:0030286	dynein complex
0.41	GO:0005929	cilium
0.38	GO:0032838	plasma membrane bounded cell projection cytoplasm
0.36	GO:0005874	microtubule
0.35	GO:0015629	actin cytoskeleton
0.30	GO:0016020	membrane

0.59	EC:3.6.1.3	GO:0016887
0.35	KEGG:R00104	GO:0003951

tr|T1G9C2|T1G9C2_HELRO
Uncharacterized protein
Search

MYL9

0.86	Regulatory myosin light chain long version

0.38	GO:0072659	protein localization to plasma membrane
0.36	GO:0007110	meiosis I cytokinesis
0.36	GO:0050793	regulation of developmental process
0.36	GO:0010172	embryonic body morphogenesis
0.36	GO:0002119	nematode larval development
0.35	GO:0065008	regulation of biological quality
0.35	GO:0030010	establishment of cell polarity
0.35	GO:0000281	mitotic cytokinesis
0.35	GO:0051128	regulation of cellular component organization
0.34	GO:0034109	homotypic cell-cell adhesion

0.70	GO:0005509	calcium ion binding
0.43	GO:0032036	myosin heavy chain binding
0.38	GO:0035254	glutamate receptor binding
0.36	GO:0008307	structural constituent of muscle
0.35	GO:0045159	myosin II binding
0.34	GO:0008484	sulfuric ester hydrolase activity
0.34	GO:0046982	protein heterodimerization activity

0.45	GO:0016460	myosin II complex
0.44	GO:0097517	contractile actin filament bundle
0.44	GO:0042641	actomyosin
0.43	GO:0030018	Z disc
0.37	GO:0099738	cell cortex region
0.36	GO:0031941	filamentous actin
0.33	GO:0005829	cytosol

0.34

EC:3.1.6

GO:0008484

tr|T1G9C3|T1G9C3_HELRO
Transporter
Search

0.47	Sodium-and chloride-dependent GABA transporter 2

0.75	GO:0006836	neurotransmitter transport
0.54	GO:0055085	transmembrane transport
0.40	GO:0006865	amino acid transport
0.39	GO:0090494	dopamine uptake
0.38	GO:0007268	chemical synaptic transmission
0.37	GO:0015718	monocarboxylic acid transport
0.36	GO:0060092	regulation of synaptic transmission, glycinergic
0.36	GO:0001505	regulation of neurotransmitter levels
0.36	GO:0098657	import into cell
0.36	GO:0007610	behavior

0.77	GO:0005328	neurotransmitter:sodium symporter activity
0.41	GO:0005343	organic acid:sodium symporter activity
0.41	GO:0015171	amino acid transmembrane transporter activity
0.39	GO:0015238	drug transmembrane transporter activity
0.38	GO:0015355	secondary active monocarboxylate transmembrane transporter activity
0.38	GO:0015296	anion:cation symporter activity
0.38	GO:0008504	monoamine transmembrane transporter activity
0.37	GO:1901618	organic hydroxy compound transmembrane transporter activity
0.37	GO:0008519	ammonium transmembrane transporter activity
0.35	GO:0072349	modified amino acid transmembrane transporter activity

0.43	GO:0005887	integral component of plasma membrane
0.38	GO:0044456	synapse part
0.37	GO:0043005	neuron projection
0.34	GO:0045121	membrane raft
0.33	GO:0005829	cytosol
0.33	GO:0012505	endomembrane system

tr|T1G9C4|T1G9C4_HELRO
Uncharacterized protein
Search

0.60	GO:0051056	regulation of small GTPase mediated signal transduction
0.58	GO:0043063	intercellular bridge organization
0.56	GO:0048260	positive regulation of receptor-mediated endocytosis
0.56	GO:0007298	border follicle cell migration
0.55	GO:0001745	compound eye morphogenesis
0.53	GO:0065009	regulation of molecular function
0.52	GO:0030036	actin cytoskeleton organization
0.52	GO:0032465	regulation of cytokinesis
0.52	GO:0097435	supramolecular fiber organization
0.52	GO:0034333	adherens junction assembly

0.60	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.55	GO:0050839	cell adhesion molecule binding
0.54	GO:0017124	SH3 domain binding
0.48	GO:0005509	calcium ion binding
0.43	GO:0004435	phosphatidylinositol phospholipase C activity
0.42	GO:0016301	kinase activity
0.38	GO:0004871	signal transducer activity
0.36	GO:0032403	protein complex binding
0.35	GO:0005516	calmodulin binding
0.35	GO:0008047	enzyme activator activity

0.55	GO:0032154	cleavage furrow
0.55	GO:0045171	intercellular bridge
0.54	GO:0030496	midbody
0.53	GO:0045179	apical cortex
0.41	GO:0015629	actin cytoskeleton
0.40	GO:0044430	cytoskeletal part
0.40	GO:0001726	ruffle
0.40	GO:0061645	endocytic patch
0.39	GO:0030863	cortical cytoskeleton
0.39	GO:0005911	cell-cell junction

0.43	EC:3.1.4.11	GO:0004435
0.43	KEGG:R03435	GO:0004435

tr|T1G9C5|T1G9C5_HELRO
Innexin
Search

INX

0.61	Innexin unc-9

0.58	GO:0006811	ion transport
0.40	GO:0007186	G-protein coupled receptor signaling pathway
0.38	GO:0010644	cell communication by electrical coupling
0.36	GO:0048598	embryonic morphogenesis
0.35	GO:0006367	transcription initiation from RNA polymerase II promoter
0.34	GO:0055085	transmembrane transport
0.34	GO:0036065	fucosylation
0.33	GO:0043413	macromolecule glycosylation
0.33	GO:0009101	glycoprotein biosynthetic process
0.32	GO:0036211	protein modification process

0.40	GO:0004930	G-protein coupled receptor activity
0.39	GO:0005243	gap junction channel activity
0.35	GO:0005509	calcium ion binding
0.34	GO:0008417	fucosyltransferase activity

0.80	GO:0005921	gap junction
0.55	GO:0005886	plasma membrane
0.36	GO:0045202	synapse
0.35	GO:0005669	transcription factor TFIID complex
0.34	GO:0032580	Golgi cisterna membrane
0.30	GO:0016021	integral component of membrane

0.34

GO:0008417

tr|T1G9C6|T1G9C6_HELRO
Uncharacterized protein
Search

0.71	Trimeric intracellular cation channel type B-B

0.62	GO:0015672	monovalent inorganic cation transport
0.61	GO:0098655	cation transmembrane transport
0.36	GO:0030001	metal ion transport
0.35	GO:0098660	inorganic ion transmembrane transport
0.34	GO:0016192	vesicle-mediated transport
0.30	GO:0009987	cellular process

0.74	GO:0005261	cation channel activity
0.37	GO:0015079	potassium ion transmembrane transporter activity
0.37	GO:0022839	ion gated channel activity
0.37	GO:0008381	mechanosensitive ion channel activity

0.30

GO:0031224

intrinsic component of membrane

tr|T1G9C7|T1G9C7_HELRO
Uncharacterized protein
Search

0.69	GO:0035335	peptidyl-tyrosine dephosphorylation
0.43	GO:0008045	motor neuron axon guidance
0.43	GO:0007424	open tracheal system development
0.41	GO:0007417	central nervous system development
0.41	GO:0007124	pseudohyphal growth
0.41	GO:0001403	invasive growth in response to glucose limitation
0.35	GO:0060275	maintenance of stationary phase in response to starvation
0.35	GO:0000256	allantoin catabolic process
0.34	GO:0000278	mitotic cell cycle
0.34	GO:0070544	histone H3-K36 demethylation

0.70	GO:0004725	protein tyrosine phosphatase activity
0.39	GO:0019198	transmembrane receptor protein phosphatase activity
0.36	GO:0008092	cytoskeletal protein binding
0.35	GO:0004037	allantoicase activity
0.34	GO:0003676	nucleic acid binding
0.34	GO:0051864	histone demethylase activity (H3-K36 specific)
0.34	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.34	GO:0004842	ubiquitin-protein transferase activity
0.34	GO:0050254	rhodopsin kinase activity
0.34	GO:0033170	protein-DNA loading ATPase activity

0.42	GO:0016324	apical plasma membrane
0.42	GO:0043025	neuronal cell body
0.42	GO:0030424	axon
0.41	GO:0005856	cytoskeleton
0.35	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm
0.34	GO:0005663	DNA replication factor C complex
0.34	GO:0016035	zeta DNA polymerase complex
0.33	GO:0099512	supramolecular fiber
0.32	GO:0019866	organelle inner membrane

0.70	EC:3.1.3.48	GO:0004725
0.35	KEGG:R02422	GO:0004037

tr|T1G9C8|T1G9C8_HELRO
Uncharacterized protein
Search

CDC23

0.82	Cell division cycle protein 23

0.76	GO:0030071	regulation of mitotic metaphase/anaphase transition
0.59	GO:0051301	cell division
0.55	GO:0070979	protein K11-linked ubiquitination
0.54	GO:0007080	mitotic metaphase plate congression
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0007091	metaphase/anaphase transition of mitotic cell cycle
0.35	GO:0007096	regulation of exit from mitosis
0.35	GO:0031145	anaphase-promoting complex-dependent catabolic process
0.34	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process

0.34	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0005515	protein binding
0.33	GO:0004872	receptor activity

0.76	GO:0005680	anaphase-promoting complex
0.33	GO:0005654	nucleoplasm
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.34

KEGG:R03876

GO:0004842

tr|T1G9C9|T1G9C9_HELRO
Guanylate cyclase
Search

0.50	Guanylate cyclase

0.81	GO:0006182	cGMP biosynthetic process
0.62	GO:0006468	protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.49	GO:0007168	receptor guanylyl cyclase signaling pathway
0.44	GO:0060038	cardiac muscle cell proliferation
0.40	GO:0018212	peptidyl-tyrosine modification
0.35	GO:0042417	dopamine metabolic process
0.35	GO:0030828	positive regulation of cGMP biosynthetic process
0.35	GO:0048662	negative regulation of smooth muscle cell proliferation

0.81	GO:0004383	guanylate cyclase activity
0.63	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0016941	natriuretic peptide receptor activity
0.46	GO:0017046	peptide hormone binding
0.42	GO:0004016	adenylate cyclase activity
0.34	GO:0019901	protein kinase binding
0.33	GO:0032550	purine ribonucleoside binding

0.45	GO:0005622	intracellular
0.43	GO:0043235	receptor complex
0.37	GO:0043234	protein complex
0.37	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.81

EC:4.6.1.2

GO:0004383

tr|T1G9D0|T1G9D0_HELRO
Uncharacterized protein
Search

0.10	DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26 (DDX26), mRNA protein

0.62

GO:0034472

snRNA 3'-end processing

0.58

GO:0004386

helicase activity

0.38

GO:0005634

nucleus

tr|T1G9D1|T1G9D1_HELRO
Uncharacterized protein
Search

0.59	Nuclear respiratory factor 1

0.54	GO:0006366	transcription by RNA polymerase II
0.54	GO:0045944	positive regulation of transcription by RNA polymerase II
0.51	GO:0014823	response to activity
0.51	GO:0045494	photoreceptor cell maintenance
0.50	GO:0003407	neural retina development
0.49	GO:0070417	cellular response to cold
0.38	GO:0007005	mitochondrion organization
0.34	GO:0006091	generation of precursor metabolites and energy

0.80	GO:0001046	core promoter sequence-specific DNA binding
0.72	GO:0042803	protein homodimerization activity
0.57	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.56	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding

0.60	GO:0005634	nucleus
0.51	GO:0005829	cytosol
0.50	GO:0031974	membrane-enclosed lumen
0.45	GO:0044446	intracellular organelle part
0.36	GO:0070062	extracellular exosome
0.35	GO:0005667	transcription factor complex

tr|T1G9D2|T1G9D2_HELRO
Uncharacterized protein
Search

tr|T1G9D3|T1G9D3_HELRO
Uncharacterized protein
Search

0.69	GO:0043547	positive regulation of GTPase activity
0.60	GO:0007165	signal transduction
0.37	GO:0035021	negative regulation of Rac protein signal transduction
0.37	GO:0001525	angiogenesis
0.37	GO:1900028	negative regulation of ruffle assembly
0.36	GO:0035313	wound healing, spreading of epidermal cells
0.35	GO:0030154	cell differentiation

0.70	GO:0005096	GTPase activator activity
0.35	GO:0035091	phosphatidylinositol binding
0.33	GO:0005515	protein binding

0.37	GO:0005925	focal adhesion
0.35	GO:0005856	cytoskeleton
0.35	GO:0042995	cell projection
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

tr|T1G9D4|T1G9D4_HELRO
Uncharacterized protein
Search

GAA

0.75	Lysosomal alpha-glucosidase

0.60	GO:0005975	carbohydrate metabolic process
0.55	GO:0043181	vacuolar sequestering
0.53	GO:0002086	diaphragm contraction
0.52	GO:0050884	neuromuscular process controlling posture
0.52	GO:0002026	regulation of the force of heart contraction
0.51	GO:0046716	muscle cell cellular homeostasis
0.51	GO:0060048	cardiac muscle contraction
0.51	GO:0050885	neuromuscular process controlling balance
0.50	GO:0007040	lysosome organization
0.49	GO:0003007	heart morphogenesis

0.69	GO:0030246	carbohydrate binding
0.66	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.34	GO:0051539	4 iron, 4 sulfur cluster binding
0.33	GO:0046872	metal ion binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003677	DNA binding

0.49	GO:0005764	lysosome
0.38	GO:0098852	lytic vacuole membrane
0.36	GO:0070062	extracellular exosome
0.35	GO:0101003	ficolin-1-rich granule membrane
0.35	GO:0070821	tertiary granule membrane
0.35	GO:0005775	vacuolar lumen
0.33	GO:0005634	nucleus
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.66

EC:3.2.1

GO:0004553

tr|T1G9D5|T1G9D5_HELRO
Uncharacterized protein
Search

KLHL5

0.87	Kelch like family member 5

0.63	GO:0007628	adult walking behavior
0.63	GO:0021680	cerebellar Purkinje cell layer development
0.60	GO:0016358	dendrite development
0.59	GO:0016567	protein ubiquitination

0.59

GO:0004842

ubiquitin-protein transferase activity

0.66	GO:0031463	Cul3-RING ubiquitin ligase complex
0.59	GO:0043025	neuronal cell body
0.59	GO:0030425	dendrite
0.56	GO:0005815	microtubule organizing center
0.41	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.59

KEGG:R03876

GO:0004842

tr|T1G9D6|T1G9D6_HELRO
Coatomer subunit beta'
Search

COPB2

0.63	Coatomer subunit beta'

0.68	GO:0006886	intracellular protein transport
0.68	GO:0016192	vesicle-mediated transport
0.50	GO:1901998	toxin transport
0.45	GO:0030903	notochord development
0.44	GO:0061053	somite development

0.61	GO:0005198	structural molecule activity
0.36	GO:0005080	protein kinase C binding
0.32	GO:0016740	transferase activity

0.75	GO:0030663	COPI-coated vesicle membrane
0.74	GO:0030117	membrane coat
0.69	GO:0000139	Golgi membrane
0.37	GO:0005829	cytosol
0.35	GO:0030133	transport vesicle
0.34	GO:0099503	secretory vesicle
0.33	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.32

EC:2

GO:0016740

tr|T1G9D7|T1G9D7_HELRO
Uncharacterized protein
Search

0.39	Carbonic anhydrase IV a

0.70	GO:0006730	one-carbon metabolic process
0.42	GO:0015670	carbon dioxide transport
0.41	GO:2000878	positive regulation of oligopeptide transport
0.41	GO:2001148	regulation of dipeptide transmembrane transport
0.41	GO:0032849	positive regulation of cellular pH reduction
0.41	GO:0044070	regulation of anion transport
0.41	GO:0038166	angiotensin-activated signaling pathway
0.40	GO:0032230	positive regulation of synaptic transmission, GABAergic
0.39	GO:0034764	positive regulation of transmembrane transport
0.39	GO:0015701	bicarbonate transport

0.76	GO:0004089	carbonate dehydratase activity
0.61	GO:0008270	zinc ion binding
0.40	GO:0004064	arylesterase activity
0.33	GO:0015035	protein disulfide oxidoreductase activity
0.33	GO:0004222	metalloendopeptidase activity
0.33	GO:0005515	protein binding
0.33	GO:0005198	structural molecule activity

0.43	GO:0031225	anchored component of membrane
0.42	GO:0005739	mitochondrion
0.42	GO:0045177	apical part of cell
0.39	GO:0043209	myelin sheath
0.39	GO:0005886	plasma membrane
0.37	GO:0070062	extracellular exosome
0.37	GO:0120025	plasma membrane bounded cell projection
0.37	GO:0005829	cytosol
0.37	GO:0030667	secretory granule membrane
0.37	GO:0005903	brush border

0.76

EC:4.2.1.1

GO:0004089

tr|T1G9D8|T1G9D8_HELRO
Uncharacterized protein
Search

0.79	cGMP-dependent protein kinase foraging

0.63	GO:0006468	protein phosphorylation
0.37	GO:0030536	larval feeding behavior
0.37	GO:0046959	habituation
0.37	GO:0008345	larval locomotory behavior
0.37	GO:0007614	short-term memory
0.37	GO:0032095	regulation of response to food
0.36	GO:0009744	response to sucrose
0.36	GO:0007616	long-term memory
0.36	GO:0008045	motor neuron axon guidance
0.36	GO:0030510	regulation of BMP signaling pathway

0.85	GO:0004692	cGMP-dependent protein kinase activity
0.73	GO:0030553	cGMP binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.33	GO:0005886	plasma membrane
0.32	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.85

EC:2.7.11.12

GO:0004692

tr|T1G9D9|T1G9D9_HELRO
Uncharacterized protein
Search

NDUFAF5

0.40	S-adenosyl-L-methionine-dependent methyltransferase

0.61	GO:0032259	methylation
0.50	GO:0030961	peptidyl-arginine hydroxylation
0.48	GO:0032981	mitochondrial respiratory chain complex I assembly
0.36	GO:0035335	peptidyl-tyrosine dephosphorylation
0.35	GO:0006432	phenylalanyl-tRNA aminoacylation
0.35	GO:0055114	oxidation-reduction process
0.34	GO:0045454	cell redox homeostasis
0.34	GO:0019464	glycine decarboxylation via glycine cleavage system
0.33	GO:0006091	generation of precursor metabolites and energy

0.61	GO:0008168	methyltransferase activity
0.36	GO:0004725	protein tyrosine phosphatase activity
0.36	GO:0016972	thiol oxidase activity
0.36	GO:0016758	transferase activity, transferring hexosyl groups
0.35	GO:0004826	phenylalanine-tRNA ligase activity
0.34	GO:0000049	tRNA binding
0.34	GO:0016651	oxidoreductase activity, acting on NAD(P)H
0.33	GO:0005515	protein binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding

0.46	GO:0031314	extrinsic component of mitochondrial inner membrane
0.36	GO:0005783	endoplasmic reticulum
0.34	GO:0005960	glycine cleavage complex
0.30	GO:0016021	integral component of membrane

0.61

GO:0008168

tr|T1G9E0|T1G9E0_HELRO
Uncharacterized protein
Search

0.73	Ribosomal protein S6 kinase a, polypeptide 1

0.62	GO:0006468	protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.39	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.38	GO:0006915	apoptotic process
0.38	GO:0045944	positive regulation of transcription by RNA polymerase II
0.37	GO:0006974	cellular response to DNA damage stimulus
0.37	GO:2000491	positive regulation of hepatic stellate cell activation
0.37	GO:0002224	toll-like receptor signaling pathway
0.37	GO:0032496	response to lipopolysaccharide
0.34	GO:0043588	skin development

0.69	GO:0004674	protein serine/threonine kinase activity
0.64	GO:0000287	magnesium ion binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.36	GO:0019901	protein kinase binding
0.36	GO:0004712	protein serine/threonine/tyrosine kinase activity
0.34	GO:0031492	nucleosomal DNA binding

0.45	GO:0005622	intracellular
0.39	GO:0043227	membrane-bounded organelle
0.38	GO:0043233	organelle lumen
0.37	GO:0043228	non-membrane-bounded organelle
0.34	GO:1990904	ribonucleoprotein complex

0.69

GO:0004674

tr|T1G9E1|T1G9E1_HELRO
Vacuolar protein sorting-associated protein 35
Search

VPS35

0.73	Vacuolar protein sorting-associated protein 35

0.81	GO:0042147	retrograde transport, endosome to Golgi
0.65	GO:0015031	protein transport
0.63	GO:1903336	negative regulation of vacuolar transport
0.63	GO:1902822	regulation of late endosome to lysosome transport
0.62	GO:0099074	mitochondrion to lysosome transport
0.61	GO:0060161	positive regulation of dopamine receptor signaling pathway
0.61	GO:1902950	regulation of dendritic spine maintenance
0.61	GO:0043653	mitochondrial fragmentation involved in apoptotic process
0.61	GO:2000331	regulation of terminal button organization
0.60	GO:0045056	transcytosis

0.62	GO:0031748	D1 dopamine receptor binding
0.44	GO:0008565	protein transporter activity
0.35	GO:0004672	protein kinase activity
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0097367	carbohydrate derivative binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0008144	drug binding

0.84	GO:0030906	retromer, cargo-selective complex
0.68	GO:0005829	cytosol
0.62	GO:0099073	mitochondrion-derived vesicle
0.61	GO:0097422	tubular endosome
0.55	GO:0005769	early endosome
0.55	GO:0005764	lysosome
0.54	GO:0010008	endosome membrane
0.53	GO:0014069	postsynaptic density
0.52	GO:0043025	neuronal cell body
0.51	GO:0048471	perinuclear region of cytoplasm

tr|T1G9E2|T1G9E2_HELRO
Uncharacterized protein
Search

0.49	Rho GTPase-activating protein 39-like (Fragment)

0.61	GO:0007165	signal transduction
0.35	GO:0006807	nitrogen compound metabolic process
0.34	GO:0051056	regulation of small GTPase mediated signal transduction
0.34	GO:0043547	positive regulation of GTPase activity
0.32	GO:0043412	macromolecule modification
0.32	GO:0010467	gene expression
0.32	GO:0046483	heterocycle metabolic process
0.32	GO:0006725	cellular aromatic compound metabolic process
0.32	GO:1901360	organic cyclic compound metabolic process
0.30	GO:0044238	primary metabolic process

0.34	GO:0051539	4 iron, 4 sulfur cluster binding
0.34	GO:0005096	GTPase activator activity
0.32	GO:0016787	hydrolase activity
0.32	GO:0016740	transferase activity

0.67	GO:0005856	cytoskeleton
0.33	GO:0005634	nucleus
0.33	GO:0005829	cytosol
0.30	GO:0044425	membrane part

0.32

GO:0016787

tr|T1G9E3|T1G9E3_HELRO
Uncharacterized protein
Search

0.66	Nuclear protein 1

0.61	GO:2000194	regulation of female gonad development
0.61	GO:0048147	negative regulation of fibroblast proliferation
0.60	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
0.59	GO:0002526	acute inflammatory response
0.59	GO:0035914	skeletal muscle cell differentiation
0.58	GO:0008584	male gonad development
0.56	GO:0008283	cell proliferation
0.55	GO:0043065	positive regulation of apoptotic process
0.54	GO:0045786	negative regulation of cell cycle
0.54	GO:0006473	protein acetylation

0.55	GO:0003677	DNA binding
0.54	GO:0003682	chromatin binding

0.52	GO:0032993	protein-DNA complex
0.50	GO:0005829	cytosol
0.46	GO:0005634	nucleus

tr|T1G9E4|T1G9E4_HELRO
Uncharacterized protein
Search

0.53	GO:0055114	oxidation-reduction process
0.33	GO:0035023	regulation of Rho protein signal transduction
0.32	GO:0065009	regulation of molecular function
0.32	GO:0071897	DNA biosynthetic process
0.32	GO:0006260	DNA replication

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.67	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.33	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.33	GO:0003887	DNA-directed DNA polymerase activity
0.32	GO:0003677	DNA binding

0.33	GO:0005789	endoplasmic reticulum membrane
0.32	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.68

EC:1.14

GO:0016705

tr|T1G9E5|T1G9E5_HELRO
Cytoplasmic tRNA 2-thiolation protein 1
Search

NCS6

0.74	Cytoplasmic tRNA 2-thiolation protein 1

0.80	GO:0032447	protein urmylation
0.78	GO:0034227	tRNA thio-modification
0.77	GO:0002098	tRNA wobble uridine modification

0.69	GO:0000049	tRNA binding
0.60	GO:0016779	nucleotidyltransferase activity
0.34	GO:0030554	adenyl nucleotide binding
0.33	GO:0097367	carbohydrate derivative binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0016787	hydrolase activity

0.47	GO:0005737	cytoplasm
0.33	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.60

EC:2.7.7

GO:0016779

tr|T1G9E6|T1G9E6_HELRO
Uncharacterized protein
Search

tr|T1G9E7|T1G9E7_HELRO
Uncharacterized protein
Search

0.48	GO:0048699	generation of neurons
0.47	GO:0010720	positive regulation of cell development
0.47	GO:0051962	positive regulation of nervous system development
0.47	GO:0000122	negative regulation of transcription by RNA polymerase II
0.43	GO:0048106	establishment of thoracic bristle planar orientation
0.42	GO:0007403	glial cell fate determination
0.42	GO:0048867	stem cell fate determination
0.42	GO:0008586	imaginal disc-derived wing vein morphogenesis
0.41	GO:0007379	segment specification
0.41	GO:0035222	wing disc pattern formation

0.57	GO:0003723	RNA binding
0.49	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.48	GO:0001085	RNA polymerase II transcription factor binding
0.36	GO:0003714	transcription corepressor activity
0.36	GO:0003697	single-stranded DNA binding
0.35	GO:0003700	DNA binding transcription factor activity
0.34	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.34	GO:0044212	transcription regulatory region DNA binding

0.48	GO:0017053	transcriptional repressor complex
0.44	GO:0005654	nucleoplasm
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

tr|T1G9E8|T1G9E8_HELRO
Uncharacterized protein
Search

SMDT1

0.95	Single-pass membrane protein with aspartate rich tail 1

0.86	GO:0036444	mitochondrial calcium uptake
0.85	GO:0051560	mitochondrial calcium ion homeostasis
0.37	GO:0000398	mRNA splicing, via spliceosome

0.35	GO:0003723	RNA binding
0.34	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.86	GO:1990246	uniplex complex
0.57	GO:0031305	integral component of mitochondrial inner membrane
0.47	GO:0005634	nucleus
0.35	GO:0043234	protein complex
0.35	GO:0005759	mitochondrial matrix
0.34	GO:0019013	viral nucleocapsid
0.33	GO:0030529	intracellular ribonucleoprotein complex

tr|T1G9E9|T1G9E9_HELRO
DNA-directed RNA polymerase subunit beta
Search

POLR2B

0.41	DNA-directed RNA polymerase subunit beta

0.58	GO:0006351	transcription, DNA-templated
0.35	GO:0035019	somatic stem cell population maintenance
0.35	GO:0060964	regulation of gene silencing by miRNA
0.34	GO:0008543	fibroblast growth factor receptor signaling pathway
0.34	GO:0016073	snRNA metabolic process
0.34	GO:0050434	positive regulation of viral transcription
0.34	GO:0006283	transcription-coupled nucleotide-excision repair
0.34	GO:0000398	mRNA splicing, via spliceosome
0.34	GO:0006370	7-methylguanosine mRNA capping

0.70	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.65	GO:0001882	nucleoside binding
0.55	GO:0003677	DNA binding
0.49	GO:0003682	chromatin binding
0.34	GO:0005515	protein binding
0.33	GO:0003723	RNA binding
0.33	GO:0046872	metal ion binding

0.53	GO:0005665	DNA-directed RNA polymerase II, core complex
0.52	GO:0000784	nuclear chromosome, telomeric region
0.30	GO:0016020	membrane

0.70

EC:2.7.7.6

GO:0003899

tr|T1G9F0|T1G9F0_HELRO
Transgelin
Search

0.55	Transgelin

0.68	GO:0035626	juvenile hormone mediated signaling pathway
0.60	GO:0031032	actomyosin structure organization
0.44	GO:0006939	smooth muscle contraction
0.39	GO:0006298	mismatch repair

0.70	GO:0070594	juvenile hormone response element binding
0.65	GO:0003779	actin binding
0.58	GO:0005516	calmodulin binding
0.52	GO:0032403	protein complex binding
0.39	GO:0030983	mismatched DNA binding
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.43	GO:0005865	striated muscle thin filament
0.40	GO:0032300	mismatch repair complex
0.30	GO:0031224	intrinsic component of membrane

tr|T1G9F1|T1G9F1_HELRO
Uncharacterized protein
Search

tr|T1G9F2|T1G9F2_HELRO
Uncharacterized protein
Search

0.42	Betaine-aldehyde dehydrogenase

0.52

GO:0055114

oxidation-reduction process

0.77

GO:0004029

aldehyde dehydrogenase (NAD) activity

0.77

EC:1.2.1.3

GO:0004029

tr|T1G9F3|T1G9F3_HELRO
Uncharacterized protein
Search

MUT

0.45	Methylmalonyl Coenzyme A mutase

0.52	GO:0050667	homocysteine metabolic process
0.49	GO:0043547	positive regulation of GTPase activity
0.48	GO:0009791	post-embryonic development
0.34	GO:0019626	short-chain fatty acid catabolic process
0.33	GO:0009235	cobalamin metabolic process

0.80	GO:0004494	methylmalonyl-CoA mutase activity
0.75	GO:0031419	cobalamin binding
0.53	GO:0046872	metal ion binding
0.50	GO:0042803	protein homodimerization activity
0.49	GO:0072341	modified amino acid binding
0.47	GO:0003924	GTPase activity

0.42	GO:0005739	mitochondrion
0.37	GO:0043233	organelle lumen
0.36	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.80	EC:5.4.99.2	GO:0004494
0.80	KEGG:R00833	GO:0004494

tr|T1G9F4|T1G9F4_HELRO
Tyrosine--tRNA ligase
Search

YARS

0.51	Tyrosine--tRNA ligase

0.78	GO:0006437	tyrosyl-tRNA aminoacylation
0.44	GO:0010758	regulation of macrophage chemotaxis
0.43	GO:0050918	positive chemotaxis
0.33	GO:0030154	cell differentiation
0.33	GO:0006438	valyl-tRNA aminoacylation
0.33	GO:0006974	cellular response to DNA damage stimulus

0.79	GO:0004831	tyrosine-tRNA ligase activity
0.68	GO:0000049	tRNA binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0042056	chemoattractant activity
0.33	GO:0004832	valine-tRNA ligase activity

0.49	GO:0005737	cytoplasm
0.47	GO:0016604	nuclear body
0.46	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex
0.40	GO:0005615	extracellular space
0.33	GO:0035770	ribonucleoprotein granule

0.79	EC:6.1.1.1	GO:0004831
0.79	KEGG:R02918	GO:0004831

tr|T1G9F5|T1G9F5_HELRO
Uncharacterized protein
Search

0.43	Steroid sulfatase

0.36	GO:0006687	glycosphingolipid metabolic process
0.36	GO:0043687	post-translational protein modification
0.36	GO:0044703	multi-organism reproductive process
0.35	GO:0009988	cell-cell recognition
0.34	GO:0044706	multi-multicellular organism process
0.34	GO:0008202	steroid metabolic process

0.75	GO:0008484	sulfuric ester hydrolase activity
0.34	GO:0046872	metal ion binding

0.38	GO:0012505	endomembrane system
0.36	GO:0005615	extracellular space
0.36	GO:0043227	membrane-bounded organelle
0.36	GO:0043230	extracellular organelle
0.36	GO:0044444	cytoplasmic part
0.35	GO:0043229	intracellular organelle
0.34	GO:0043233	organelle lumen
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.75

EC:3.1.6

GO:0008484

tr|T1G9F6|T1G9F6_HELRO
Uncharacterized protein
Search

0.31	Flagellar hook-length control protein FliK

0.41	GO:0007275	multicellular organism development
0.41	GO:0009653	anatomical structure morphogenesis
0.39	GO:0030154	cell differentiation
0.39	GO:0030198	extracellular matrix organization
0.38	GO:0009888	tissue development
0.37	GO:0001894	tissue homeostasis
0.37	GO:0071230	cellular response to amino acid stimulus
0.37	GO:0010951	negative regulation of endopeptidase activity
0.37	GO:0061061	muscle structure development
0.37	GO:0120036	plasma membrane bounded cell projection organization

0.61	GO:0005201	extracellular matrix structural constituent
0.40	GO:0042302	structural constituent of cuticle
0.38	GO:0005509	calcium ion binding
0.37	GO:0004867	serine-type endopeptidase inhibitor activity
0.36	GO:0048407	platelet-derived growth factor binding
0.36	GO:0005178	integrin binding
0.34	GO:0017056	structural constituent of nuclear pore
0.34	GO:0046332	SMAD binding
0.34	GO:0002020	protease binding
0.34	GO:0003677	DNA binding

0.59	GO:0005581	collagen trimer
0.50	GO:0044420	extracellular matrix component
0.48	GO:0005578	proteinaceous extracellular matrix
0.35	GO:0005615	extracellular space
0.35	GO:0099081	supramolecular polymer
0.34	GO:0005643	nuclear pore
0.34	GO:0031514	motile cilium
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:6.5.1.1

GO:0003910

tr|T1G9F7|T1G9F7_HELRO
Uncharacterized protein
Search

CDK11B

0.56	Cyclin-dependent kinase 11B

0.63	GO:0006468	protein phosphorylation
0.45	GO:0034126	positive regulation of MyD88-dependent toll-like receptor signaling pathway
0.41	GO:0007224	smoothened signaling pathway
0.39	GO:0051301	cell division
0.38	GO:0051726	regulation of cell cycle
0.35	GO:0060255	regulation of macromolecule metabolic process
0.33	GO:0007049	cell cycle

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0060089	molecular transducer activity
0.33	GO:0016758	transferase activity, transferring hexosyl groups

0.36

GO:0005634

nucleus

0.33

GO:0016758

tr|T1G9F8|T1G9F8_HELRO
Uncharacterized protein
Search

EIF4G3

0.59	Eukaryotic translation initiation factor 4 gamma, 3

0.72	GO:0006413	translational initiation
0.36	GO:0060903	positive regulation of meiosis I
0.35	GO:0006417	regulation of translation
0.35	GO:0007283	spermatogenesis
0.35	GO:0034250	positive regulation of cellular amide metabolic process
0.35	GO:0001934	positive regulation of protein phosphorylation
0.35	GO:0010507	negative regulation of autophagy
0.34	GO:0010557	positive regulation of macromolecule biosynthetic process
0.34	GO:0031328	positive regulation of cellular biosynthetic process
0.34	GO:0010628	positive regulation of gene expression

0.73	GO:0003743	translation initiation factor activity
0.72	GO:0000339	RNA cap binding
0.58	GO:0003729	mRNA binding

0.30

GO:0016020

membrane

tr|T1G9F9|T1G9F9_HELRO
Uncharacterized protein
Search

DYRK2

0.91	Dual specificity tyrosine-phosphorylation-regulated kinase 2

0.60	GO:0006468	protein phosphorylation
0.57	GO:0051534	negative regulation of NFAT protein import into nucleus
0.56	GO:0045725	positive regulation of glycogen biosynthetic process
0.55	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
0.53	GO:0007224	smoothened signaling pathway
0.50	GO:0018212	peptidyl-tyrosine modification
0.38	GO:1901796	regulation of signal transduction by p53 class mediator
0.37	GO:0035617	stress granule disassembly
0.37	GO:2001021	negative regulation of response to DNA damage stimulus
0.37	GO:0030218	erythrocyte differentiation

0.61	GO:0004672	protein kinase activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0030145	manganese ion binding
0.46	GO:0000287	magnesium ion binding
0.33	GO:0005515	protein binding

0.50	GO:0000151	ubiquitin ligase complex
0.48	GO:0005654	nucleoplasm
0.47	GO:0005829	cytosol
0.43	GO:0030529	intracellular ribonucleoprotein complex
0.34	GO:0043232	intracellular non-membrane-bounded organelle

tr|T1G9G0|T1G9G0_HELRO
Uncharacterized protein
Search

0.47	Discoidin domain-containing receptor 2

0.74	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.73	GO:0018108	peptidyl-tyrosine phosphorylation
0.52	GO:0010715	regulation of extracellular matrix disassembly
0.49	GO:0010763	positive regulation of fibroblast migration
0.48	GO:0035988	chondrocyte proliferation
0.48	GO:1903055	positive regulation of extracellular matrix organization
0.48	GO:0046777	protein autophosphorylation
0.48	GO:0003416	endochondral bone growth
0.48	GO:0048146	positive regulation of fibroblast proliferation
0.47	GO:0031214	biomineral tissue development

0.75	GO:0038062	protein tyrosine kinase collagen receptor activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0005518	collagen binding
0.35	GO:0070569	uridylyltransferase activity
0.33	GO:0046872	metal ion binding

0.58	GO:0005887	integral component of plasma membrane
0.43	GO:0015629	actin cytoskeleton
0.38	GO:0043235	receptor complex
0.37	GO:0098590	plasma membrane region
0.37	GO:0045177	apical part of cell
0.36	GO:0070062	extracellular exosome
0.35	GO:0005925	focal adhesion

tr|T1G9G1|T1G9G1_HELRO
Uncharacterized protein
Search

0.82

GO:0007160

cell-matrix adhesion

0.54

GO:0046872

metal ion binding

0.69

GO:0005856

cytoskeleton

tr|T1G9G2|T1G9G2_HELRO
Uncharacterized protein
Search

ABCG2

0.86	Placenta-specific ATP-binding cassette transporter

0.51	GO:0055085	transmembrane transport
0.50	GO:0046415	urate metabolic process
0.49	GO:0033344	cholesterol efflux
0.44	GO:0015893	drug transport
0.38	GO:0097744	urate salt excretion
0.37	GO:1904612	response to 2,3,7,8-tetrachlorodibenzodioxine
0.37	GO:0019389	glucuronoside metabolic process
0.37	GO:1904479	negative regulation of intestinal absorption
0.37	GO:0060136	embryonic process involved in female pregnancy
0.37	GO:0051593	response to folic acid

0.61	GO:0016887	ATPase activity
0.60	GO:0015399	primary active transmembrane transporter activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0017127	cholesterol transporter activity
0.46	GO:0042803	protein homodimerization activity
0.37	GO:0042910	xenobiotic transmembrane transporter activity
0.37	GO:0015238	drug transmembrane transporter activity
0.35	GO:0008092	cytoskeletal protein binding

0.47	GO:0016324	apical plasma membrane
0.46	GO:0043235	receptor complex
0.42	GO:0005634	nucleus
0.36	GO:0031966	mitochondrial membrane
0.35	GO:0043190	ATP-binding cassette (ABC) transporter complex

0.61

GO:0016887

tr|T1G9G3|T1G9G3_HELRO
Uncharacterized protein
Search

0.54	Transcription factor protein (Fragment)

0.82	GO:0051568	histone H3-K4 methylation
0.35	GO:1903506	regulation of nucleic acid-templated transcription
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression
0.34	GO:0040028	regulation of vulval development
0.32	GO:0030163	protein catabolic process

0.84	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.51	GO:0046872	metal ion binding
0.48	GO:0046983	protein dimerization activity
0.32	GO:0003676	nucleic acid binding
0.31	GO:0030554	adenyl nucleotide binding
0.31	GO:0032555	purine ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding
0.31	GO:0016787	hydrolase activity

0.82	GO:0044666	MLL3/4 complex
0.31	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.31

GO:0016787

tr|T1G9G4|T1G9G4_HELRO
Uncharacterized protein
Search

MCTP1

0.86	Multiple C2 and transmembrane domain-containing protein 1

0.35	GO:0045806	negative regulation of endocytosis
0.35	GO:1902883	negative regulation of response to oxidative stress
0.35	GO:0046928	regulation of neurotransmitter secretion
0.35	GO:0048168	regulation of neuronal synaptic plasticity
0.35	GO:0019722	calcium-mediated signaling
0.35	GO:0030336	negative regulation of cell migration

0.45	GO:0005509	calcium ion binding
0.35	GO:0005544	calcium-dependent phospholipid binding

0.41	GO:0005783	endoplasmic reticulum
0.35	GO:0030672	synaptic vesicle membrane
0.35	GO:0055037	recycling endosome
0.34	GO:0030054	cell junction
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

tr|T1G9G5|T1G9G5_HELRO
Uncharacterized protein
Search

0.56	GO:0006508	proteolysis
0.40	GO:0061036	positive regulation of cartilage development
0.37	GO:0048632	negative regulation of skeletal muscle tissue growth
0.37	GO:0007585	respiratory gaseous exchange
0.36	GO:0051216	cartilage development
0.36	GO:0001503	ossification
0.36	GO:0042953	lipoprotein transport
0.35	GO:0010469	regulation of receptor activity
0.35	GO:0006898	receptor-mediated endocytosis
0.35	GO:0030154	cell differentiation

0.69	GO:0005509	calcium ion binding
0.64	GO:0004222	metalloendopeptidase activity
0.57	GO:0008270	zinc ion binding
0.39	GO:0042802	identical protein binding
0.36	GO:0005125	cytokine activity
0.36	GO:0008083	growth factor activity
0.35	GO:0046983	protein dimerization activity
0.34	GO:0003676	nucleic acid binding
0.34	GO:0016874	ligase activity

0.40	GO:0005615	extracellular space
0.37	GO:0005794	Golgi apparatus
0.37	GO:0005903	brush border
0.36	GO:0016324	apical plasma membrane
0.36	GO:0030139	endocytic vesicle
0.36	GO:1903561	extracellular vesicle
0.36	GO:0005905	clathrin-coated pit
0.36	GO:0005768	endosome
0.35	GO:0005578	proteinaceous extracellular matrix
0.35	GO:0005783	endoplasmic reticulum

0.64

GO:0004222

tr|T1G9G6|T1G9G6_HELRO
Uncharacterized protein
Search

0.29	Phosphodiesterase

0.61	GO:0007165	signal transduction
0.35	GO:0046069	cGMP catabolic process
0.34	GO:0035041	sperm chromatin decondensation
0.33	GO:0007143	female meiotic nuclear division
0.33	GO:0006397	mRNA processing
0.33	GO:1902275	regulation of chromatin organization
0.33	GO:0006357	regulation of transcription by RNA polymerase II

0.80	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.54	GO:0046872	metal ion binding
0.33	GO:0003682	chromatin binding
0.32	GO:0043565	sequence-specific DNA binding

0.33	GO:0000228	nuclear chromosome
0.31	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.80

EC:3.1.4.17

GO:0004114

tr|T1G9G7|T1G9G7_HELRO
Uncharacterized protein
Search

0.61	GO:0006887	exocytosis
0.59	GO:0006886	intracellular protein transport
0.48	GO:0070073	clustering of voltage-gated calcium channels
0.46	GO:0007274	neuromuscular synaptic transmission
0.45	GO:0048167	regulation of synaptic plasticity
0.45	GO:0048489	synaptic vesicle transport
0.45	GO:0099504	synaptic vesicle cycle
0.45	GO:0099643	signal release from synapse
0.45	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.43	GO:0006836	neurotransmitter transport

0.75	GO:0017137	Rab GTPase binding
0.50	GO:0046872	metal ion binding
0.35	GO:0044325	ion channel binding
0.33	GO:0016301	kinase activity

0.66	GO:0048786	presynaptic active zone
0.42	GO:0008021	synaptic vesicle
0.41	GO:0099569	presynaptic cytoskeleton
0.39	GO:0099738	cell cortex region
0.39	GO:0030863	cortical cytoskeleton
0.30	GO:0016020	membrane

tr|T1G9G8|T1G9G8_HELRO
Uncharacterized protein
Search

0.59	Sorting nexin

0.69	GO:0006886	intracellular protein transport
0.49	GO:1990126	retrograde transport, endosome to plasma membrane
0.44	GO:0007165	signal transduction
0.32	GO:0006468	protein phosphorylation

0.77	GO:0035091	phosphatidylinositol binding
0.34	GO:0005515	protein binding
0.32	GO:0004674	protein serine/threonine kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.46	GO:0005769	early endosome
0.41	GO:0043234	protein complex
0.38	GO:0005856	cytoskeleton
0.30	GO:0016020	membrane

0.32

GO:0004674

tr|T1G9G9|T1G9G9_HELRO
Uncharacterized protein
Search

0.80	Serine/arginine-rich splicing factor 1

0.35	GO:0009792	embryo development ending in birth or egg hatching
0.34	GO:0008380	RNA splicing
0.34	GO:0006397	mRNA processing
0.34	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.34	GO:0022618	ribonucleoprotein complex assembly
0.33	GO:0019079	viral genome replication

0.59	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.34	GO:0071986	Ragulator complex
0.33	GO:0005634	nucleus
0.32	GO:0030529	intracellular ribonucleoprotein complex

tr|T1G9H0|T1G9H0_HELRO
Uncharacterized protein
Search

0.56	GO:0007053	spindle assembly involved in male meiosis
0.56	GO:0036090	cleavage furrow ingression
0.55	GO:0045887	positive regulation of synaptic growth at neuromuscular junction
0.54	GO:0007112	male meiosis cytokinesis
0.53	GO:0016310	phosphorylation
0.51	GO:0000281	mitotic cytokinesis
0.44	GO:0030100	regulation of endocytosis
0.40	GO:0048488	synaptic vesicle endocytosis
0.39	GO:0099643	signal release from synapse
0.39	GO:0099531	presynaptic process involved in chemical synaptic transmission

0.56	GO:0016301	kinase activity
0.48	GO:0008289	lipid binding
0.38	GO:0005515	protein binding
0.34	GO:0043168	anion binding
0.32	GO:0046872	metal ion binding

0.56	GO:0071212	subsynaptic reticulum
0.53	GO:0032154	cleavage furrow
0.52	GO:0030496	midbody
0.50	GO:0045211	postsynaptic membrane
0.42	GO:0005768	endosome
0.33	GO:0031514	motile cilium
0.30	GO:0016021	integral component of membrane

tr|T1G9H1|T1G9H1_HELRO
Uncharacterized protein
Search

0.63	GO:0006468	protein phosphorylation
0.60	GO:0045719	negative regulation of glycogen biosynthetic process
0.59	GO:0050849	negative regulation of calcium-mediated signaling
0.59	GO:0007089	traversing start control point of mitotic cell cycle
0.58	GO:0071073	positive regulation of phospholipid biosynthetic process
0.58	GO:0016242	negative regulation of macroautophagy
0.57	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle
0.57	GO:0016239	positive regulation of macroautophagy
0.56	GO:0043433	negative regulation of DNA binding transcription factor activity
0.54	GO:0031647	regulation of protein stability

0.64	GO:0004672	protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0060089	molecular transducer activity
0.40	GO:0004722	protein serine/threonine phosphatase activity
0.35	GO:0004871	signal transducer activity
0.35	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.35	GO:0003676	nucleic acid binding

0.60	GO:1990860	Pho85-Pho80 CDK-cyclin complex
0.46	GO:0005634	nucleus
0.36	GO:0032153	cell division site
0.35	GO:0030428	cell septum
0.35	GO:0051286	cell tip
0.34	GO:0005737	cytoplasm
0.33	GO:0005871	kinesin complex
0.30	GO:0016020	membrane

0.35

GO:0003755

tr|T1G9H2|T1G9H2_HELRO
Uncharacterized protein
Search

0.37

Boudin

0.37

GO:0007186

G-protein coupled receptor signaling pathway

0.39

GO:0008528

G-protein coupled peptide receptor activity

0.41	GO:0009986	cell surface
0.30	GO:0044425	membrane part

tr|T1G9H3|T1G9H3_HELRO
Uncharacterized protein
Search

0.61	GO:0006508	proteolysis
0.47	GO:0009405	pathogenesis
0.41	GO:0097186	amelogenesis
0.40	GO:0022617	extracellular matrix disassembly
0.40	GO:0050878	regulation of body fluid levels
0.40	GO:2000097	regulation of smooth muscle cell-matrix adhesion
0.40	GO:0014909	smooth muscle cell migration
0.39	GO:0050819	negative regulation of coagulation
0.39	GO:0061045	negative regulation of wound healing
0.39	GO:0014910	regulation of smooth muscle cell migration

0.69	GO:0004252	serine-type endopeptidase activity
0.49	GO:0090729	toxin activity
0.35	GO:0005509	calcium ion binding
0.34	GO:0005515	protein binding
0.34	GO:0016301	kinase activity
0.34	GO:0005057	signal transducer activity, downstream of receptor
0.33	GO:0008201	heparin binding

0.48	GO:0005576	extracellular region
0.39	GO:0030141	secretory granule
0.37	GO:0009986	cell surface
0.35	GO:0097223	sperm part
0.35	GO:0045177	apical part of cell
0.34	GO:0005925	focal adhesion
0.34	GO:0005766	primary lysosome
0.34	GO:0060205	cytoplasmic vesicle lumen
0.34	GO:0005775	vacuolar lumen
0.34	GO:0005634	nucleus

0.69

EC:3.4.21

GO:0004252

tr|T1G9H4|T1G9H4_HELRO
Uncharacterized protein
Search

UBA1

0.79	Ubiquitin activating enzyme

0.60	GO:0036211	protein modification process
0.56	GO:0044267	cellular protein metabolic process
0.46	GO:0006974	cellular response to DNA damage stimulus
0.45	GO:0048666	neuron development
0.43	GO:0043632	modification-dependent macromolecule catabolic process
0.43	GO:0009653	anatomical structure morphogenesis
0.43	GO:0030163	protein catabolic process
0.42	GO:0120036	plasma membrane bounded cell projection organization
0.40	GO:0016319	mushroom body development
0.40	GO:0010623	programmed cell death involved in cell development

0.76	GO:0008641	ubiquitin-like modifier activating enzyme activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0003910	DNA ligase (ATP) activity
0.34	GO:0003723	RNA binding
0.34	GO:0005515	protein binding
0.33	GO:0003677	DNA binding
0.32	GO:0046872	metal ion binding

0.52	GO:0030057	desmosome
0.50	GO:0030867	rough endoplasmic reticulum membrane
0.50	GO:0000792	heterochromatin
0.50	GO:0005765	lysosomal membrane
0.48	GO:0010008	endosome membrane
0.45	GO:0005654	nucleoplasm
0.45	GO:0005829	cytosol
0.42	GO:0005739	mitochondrion
0.39	GO:0030425	dendrite
0.36	GO:0070062	extracellular exosome

0.35

EC:6.5.1.1

GO:0003910

tr|T1G9H5|T1G9H5_HELRO
Uncharacterized protein
Search

0.65	ATP-dependent RNA and DNA helicase

0.57	GO:0000965	mitochondrial RNA 3'-end processing
0.49	GO:0035945	mitochondrial ncRNA surveillance
0.49	GO:0035946	mitochondrial mRNA surveillance
0.48	GO:0000962	positive regulation of mitochondrial RNA catabolic process
0.48	GO:0000958	mitochondrial mRNA catabolic process
0.47	GO:0044528	regulation of mitochondrial mRNA stability
0.47	GO:0090615	mitochondrial mRNA processing
0.47	GO:0070827	chromatin maintenance
0.46	GO:0070584	mitochondrion morphogenesis
0.46	GO:0090646	mitochondrial tRNA processing

0.58	GO:0016817	hydrolase activity, acting on acid anhydrides
0.43	GO:0003725	double-stranded RNA binding
0.42	GO:0042803	protein homodimerization activity
0.41	GO:0140098	catalytic activity, acting on RNA
0.40	GO:0140097	catalytic activity, acting on DNA
0.38	GO:0003677	DNA binding
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.51	GO:0045025	mitochondrial degradosome
0.45	GO:0042645	mitochondrial nucleoid
0.40	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.58

EC:3.6

GO:0016817

tr|T1G9H6|T1G9H6_HELRO
Uncharacterized protein
Search

USP7

0.53	Ubiquitin carboxyl-terminal hydrolase

0.76	GO:0016579	protein deubiquitination
0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.54	GO:0010216	maintenance of DNA methylation
0.52	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.52	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process
0.50	GO:0050821	protein stabilization
0.50	GO:0006283	transcription-coupled nucleotide-excision repair
0.43	GO:1904888	cranial skeletal system development
0.37	GO:0016570	histone modification
0.36	GO:0007275	multicellular organism development

0.77	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.52	GO:0002039	p53 binding
0.51	GO:0008022	protein C-terminus binding
0.50	GO:0031625	ubiquitin protein ligase binding
0.48	GO:0004197	cysteine-type endopeptidase activity
0.47	GO:0008134	transcription factor binding
0.34	GO:0042803	protein homodimerization activity
0.34	GO:0003755	peptidyl-prolyl cis-trans isomerase activity

0.45	GO:0005829	cytosol
0.43	GO:0005634	nucleus
0.41	GO:0043234	protein complex
0.37	GO:0001741	XY body
0.36	GO:0031974	membrane-enclosed lumen
0.34	GO:0044446	intracellular organelle part

0.77

EC:3.4.19.12

GO:0036459

tr|T1G9H7|T1G9H7_HELRO
Uncharacterized protein
Search

EML1

0.86	Echinoderm microtubule associated protein like 1

0.74	GO:0007405	neuroblast proliferation
0.72	GO:0002244	hematopoietic progenitor cell differentiation
0.71	GO:0007052	mitotic spindle organization
0.69	GO:0007420	brain development
0.49	GO:0010968	regulation of microtubule nucleation
0.49	GO:0031115	negative regulation of microtubule polymerization
0.44	GO:0036368	cone photoresponse recovery

0.69	GO:0008017	microtubule binding
0.38	GO:0008022	protein C-terminus binding
0.37	GO:0005102	receptor binding
0.37	GO:0005509	calcium ion binding
0.30	GO:0003824	catalytic activity

0.74	GO:0097431	mitotic spindle pole
0.73	GO:1990023	mitotic spindle midzone
0.60	GO:0005829	cytosol
0.48	GO:0005874	microtubule
0.43	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0005875	microtubule associated complex
0.30	GO:0016020	membrane

tr|T1G9H8|T1G9H8_HELRO
Uncharacterized protein
Search

0.67	GO:0060071	Wnt signaling pathway, planar cell polarity pathway
0.67	GO:0060026	convergent extension
0.66	GO:0001736	establishment of planar polarity
0.61	GO:0018108	peptidyl-tyrosine phosphorylation
0.49	GO:0048731	system development
0.49	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.47	GO:0007155	cell adhesion
0.42	GO:0030154	cell differentiation
0.41	GO:0006413	translational initiation
0.41	GO:0002376	immune system process

0.69	GO:1904929	coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway
0.61	GO:0004713	protein tyrosine kinase activity
0.52	GO:0030554	adenyl nucleotide binding
0.52	GO:0019199	transmembrane receptor protein kinase activity
0.51	GO:0097367	carbohydrate derivative binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0003743	translation initiation factor activity
0.38	GO:0005515	protein binding
0.36	GO:0017108	5'-flap endonuclease activity

0.56	GO:0005887	integral component of plasma membrane
0.42	GO:0005852	eukaryotic translation initiation factor 3 complex
0.36	GO:0009986	cell surface
0.35	GO:0005730	nucleolus
0.35	GO:0005654	nucleoplasm
0.34	GO:0005739	mitochondrion
0.34	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.33	GO:0005783	endoplasmic reticulum
0.33	GO:0030426	growth cone
0.33	GO:0030424	axon

0.61

EC:2.7.10

GO:0004713

tr|T1G9H9|T1G9H9_HELRO
Uncharacterized protein
Search

MED17

0.64	Mediator of RNA polymerase II transcription subunit 17

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.57	GO:0006351	transcription, DNA-templated
0.46	GO:0019827	stem cell population maintenance
0.45	GO:0045498	sex comb development
0.42	GO:0045893	positive regulation of transcription, DNA-templated
0.37	GO:0030521	androgen receptor signaling pathway
0.34	GO:0016567	protein ubiquitination

0.79	GO:0001104	RNA polymerase II transcription cofactor activity
0.43	GO:0033613	activating transcription factor binding
0.43	GO:0003713	transcription coactivator activity
0.38	GO:0046966	thyroid hormone receptor binding
0.35	GO:0004872	receptor activity
0.34	GO:0061630	ubiquitin protein ligase activity
0.34	GO:0042809	vitamin D receptor binding

0.77	GO:0016592	mediator complex
0.43	GO:0031618	nuclear pericentric heterochromatin
0.36	GO:0005667	transcription factor complex
0.34	GO:0000151	ubiquitin ligase complex
0.30	GO:0016020	membrane

tr|T1G9I0|T1G9I0_HELRO
Uncharacterized protein
Search

TIAL1

0.72	Apoptosis-promoting RNA-binding protein TIA-1/TIAR

0.44	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.33	GO:0006508	proteolysis
0.32	GO:0055114	oxidation-reduction process

0.59	GO:0003723	RNA binding
0.33	GO:0070001	aspartic-type peptidase activity
0.33	GO:0004175	endopeptidase activity
0.32	GO:0016491	oxidoreductase activity

0.33	GO:0019013	viral nucleocapsid
0.32	GO:0030529	intracellular ribonucleoprotein complex

0.32

GO:0016491

tr|T1G9I1|T1G9I1_HELRO
Uncharacterized protein
Search

0.40	Sodium-dependent phosphate transport protein 1

0.55	GO:0055085	transmembrane transport
0.42	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.37	GO:0006820	anion transport

0.45	GO:0008408	3'-5' exonuclease activity
0.43	GO:0005215	transporter activity
0.38	GO:0000166	nucleotide binding
0.38	GO:0003676	nucleic acid binding

0.36	GO:0005622	intracellular
0.30	GO:0016020	membrane

tr|T1G9I2|T1G9I2_HELRO
Uncharacterized protein
Search

0.80	Alpha-actinin, sarcomeric

0.36	GO:0051017	actin filament bundle assembly
0.34	GO:0051764	actin crosslink formation
0.33	GO:0035335	peptidyl-tyrosine dephosphorylation
0.32	GO:0007186	G-protein coupled receptor signaling pathway

0.74	GO:0003779	actin binding
0.69	GO:0005509	calcium ion binding
0.35	GO:0019863	IgE binding
0.33	GO:0004725	protein tyrosine phosphatase activity
0.32	GO:0004930	G-protein coupled receptor activity

0.35	GO:0055120	striated muscle dense body
0.34	GO:0005865	striated muscle thin filament
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:3.1.3.48

GO:0004725

tr|T1G9I3|T1G9I3_HELRO
Uncharacterized protein
Search

CUL5

0.82

Cullin-5

0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.45	GO:0016567	protein ubiquitination
0.42	GO:0006974	cellular response to DNA damage stimulus
0.35	GO:0021942	radial glia guided migration of Purkinje cell
0.35	GO:0038128	ERBB2 signaling pathway
0.35	GO:0021799	cerebral cortex radially oriented cell migration
0.35	GO:0097193	intrinsic apoptotic signaling pathway
0.35	GO:0007050	cell cycle arrest
0.35	GO:0000082	G1/S transition of mitotic cell cycle
0.34	GO:0051480	regulation of cytosolic calcium ion concentration

0.79	GO:0031625	ubiquitin protein ligase binding
0.46	GO:0061630	ubiquitin protein ligase activity
0.35	GO:0005000	vasopressin receptor activity
0.34	GO:0005262	calcium channel activity
0.34	GO:0046982	protein heterodimerization activity
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0032561	guanyl ribonucleotide binding
0.33	GO:0003700	DNA binding transcription factor activity
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.77	GO:0031461	cullin-RING ubiquitin ligase complex
0.33	GO:0005829	cytosol
0.33	GO:0005634	nucleus
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1G9I4|T1G9I4_HELRO
Uncharacterized protein
Search

ALYREF

0.78	THO complex subunit 4-A

0.37	GO:0050790	regulation of catalytic activity
0.36	GO:0046784	viral mRNA export from host cell nucleus
0.36	GO:0001649	osteoblast differentiation
0.36	GO:0031297	replication fork processing
0.35	GO:0032786	positive regulation of DNA-templated transcription, elongation
0.35	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.35	GO:0000018	regulation of DNA recombination
0.35	GO:0051028	mRNA transport
0.35	GO:0006405	RNA export from nucleus
0.33	GO:0010467	gene expression

0.59	GO:0003723	RNA binding
0.40	GO:0005094	Rho GDP-dissociation inhibitor activity
0.35	GO:0003697	single-stranded DNA binding
0.33	GO:0004252	serine-type endopeptidase activity

0.37	GO:0016607	nuclear speck
0.36	GO:0035145	exon-exon junction complex
0.36	GO:0000346	transcription export complex
0.35	GO:0071013	catalytic step 2 spliceosome
0.35	GO:0000784	nuclear chromosome, telomeric region
0.35	GO:0070062	extracellular exosome
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.33

EC:3.4.21

GO:0004252

tr|T1G9I5|T1G9I5_HELRO
Solute carrier organic anion transporter family member
Search

0.38	Solute carrier organic anion transporter family member

0.58	GO:0006811	ion transport
0.55	GO:0055085	transmembrane transport
0.41	GO:0071702	organic substance transport
0.39	GO:0070327	thyroid hormone transport
0.37	GO:0007283	spermatogenesis
0.36	GO:0030154	cell differentiation
0.36	GO:0010876	lipid localization
0.36	GO:0007275	multicellular organism development
0.35	GO:0042403	thyroid hormone metabolic process
0.34	GO:0043312	neutrophil degranulation

0.56

GO:0005215

transporter activity

0.55	GO:0005886	plasma membrane
0.35	GO:0070062	extracellular exosome
0.34	GO:0035579	specific granule membrane
0.34	GO:0035577	azurophil granule membrane
0.30	GO:0016021	integral component of membrane

tr|T1G9I6|T1G9I6_HELRO
Uncharacterized protein
Search

0.58	Splicing factor, arginine/serine-rich 7

0.63	GO:0008270	zinc ion binding
0.59	GO:0003723	RNA binding

tr|T1G9I7|T1G9I7_HELRO
Uncharacterized protein
Search

SRSF2

0.92	Serine and arginine rich splicing factor 2

0.73	GO:0043484	regulation of RNA splicing
0.47	GO:0050684	regulation of mRNA processing
0.43	GO:0001178	regulation of transcriptional start site selection at RNA polymerase II promoter
0.39	GO:0033197	response to vitamin E
0.38	GO:0008380	RNA splicing
0.38	GO:0006397	mRNA processing
0.37	GO:0000278	mitotic cell cycle
0.34	GO:0006369	termination of RNA polymerase II transcription
0.34	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.34	GO:0050482	arachidonic acid secretion

0.59	GO:0003723	RNA binding
0.38	GO:0005080	protein kinase C binding
0.34	GO:0016787	hydrolase activity
0.34	GO:0003714	transcription corepressor activity
0.32	GO:0008270	zinc ion binding
0.32	GO:0016874	ligase activity
0.32	GO:0016491	oxidoreductase activity

0.49	GO:0016607	nuclear speck
0.44	GO:0005681	spliceosomal complex
0.42	GO:0005829	cytosol
0.39	GO:0000785	chromatin
0.39	GO:0035061	interchromatin granule
0.36	GO:0016605	PML body
0.35	GO:0070062	extracellular exosome
0.34	GO:0019013	viral nucleocapsid
0.30	GO:0016020	membrane

0.34

GO:0016787

tr|T1G9I8|T1G9I8_HELRO
Uncharacterized protein
Search

0.84	Fragile X mental retardation, autosomal homolog 1

0.38	GO:0017148	negative regulation of translation
0.37	GO:0003002	regionalization
0.37	GO:0031644	regulation of neurological system process
0.37	GO:0009790	embryo development
0.37	GO:0048646	anatomical structure formation involved in morphogenesis
0.37	GO:0048468	cell development
0.37	GO:0050773	regulation of dendrite development
0.37	GO:0048513	animal organ development
0.36	GO:1901254	positive regulation of intracellular transport of viral material
0.36	GO:1903311	regulation of mRNA metabolic process

0.59	GO:0003723	RNA binding
0.36	GO:0045182	translation regulator activity
0.35	GO:0044325	ion channel binding
0.35	GO:0097617	annealing activity
0.35	GO:0042802	identical protein binding
0.35	GO:0140034	methylation-dependent protein binding
0.35	GO:0031369	translation initiation factor binding
0.35	GO:0042393	histone binding
0.34	GO:0046982	protein heterodimerization activity
0.34	GO:0043022	ribosome binding

0.39	GO:0005844	polysome
0.37	GO:0043204	perikaryon
0.36	GO:0019034	viral replication complex
0.36	GO:0036464	cytoplasmic ribonucleoprotein granule
0.36	GO:1990124	messenger ribonucleoprotein complex
0.36	GO:0005634	nucleus
0.36	GO:0043005	neuron projection
0.36	GO:0120038	plasma membrane bounded cell projection part
0.36	GO:0032797	SMN complex
0.35	GO:0030427	site of polarized growth

tr|T1G9I9|T1G9I9_HELRO
Uncharacterized protein
Search

NFXL1

0.63	Nuclear transcription factor, X-box binding like 1

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.46	GO:0006366	transcription by RNA polymerase II
0.44	GO:1902679	negative regulation of RNA biosynthetic process
0.32	GO:0034220	ion transmembrane transport

0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.46	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.32	GO:0005216	ion channel activity

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|T1G9J0|T1G9J0_HELRO
Uncharacterized protein
Search

SYMPK

0.47

Symplekin

0.81	GO:0035307	positive regulation of protein dephosphorylation
0.77	GO:0006378	mRNA polyadenylation
0.41	GO:0007155	cell adhesion
0.41	GO:0006369	termination of RNA polymerase II transcription
0.40	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.39	GO:0051028	mRNA transport
0.39	GO:0000398	mRNA splicing, via spliceosome
0.39	GO:0006405	RNA export from nucleus
0.36	GO:0055114	oxidation-reduction process

0.39	GO:0005515	protein binding
0.36	GO:0016491	oxidoreductase activity

0.85	GO:0097165	nuclear stress granule
0.68	GO:0005654	nucleoplasm
0.66	GO:0005829	cytosol
0.54	GO:0005886	plasma membrane
0.44	GO:0005923	bicellular tight junction
0.41	GO:0005856	cytoskeleton
0.30	GO:0016021	integral component of membrane

0.36

GO:0016491

tr|T1G9J1|T1G9J1_HELRO
Uncharacterized protein
Search

CNOT6

0.85	CCR4-NOT transcription complex subunit 6 like

0.71	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic
0.60	GO:2000327	positive regulation of ligand-dependent nuclear receptor transcription coactivator activity
0.58	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly
0.57	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
0.56	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay
0.56	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening
0.53	GO:0008284	positive regulation of cell proliferation
0.40	GO:0006417	regulation of translation
0.40	GO:0031047	gene silencing by RNA
0.39	GO:0050779	RNA destabilization

0.79	GO:0004535	poly(A)-specific ribonuclease activity
0.35	GO:0003723	RNA binding
0.35	GO:0046872	metal ion binding
0.33	GO:0004930	G-protein coupled receptor activity
0.33	GO:0005515	protein binding

0.56	GO:0030014	CCR4-NOT complex
0.38	GO:0005634	nucleus
0.37	GO:0005829	cytosol
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.79

EC:3.1.13.4

GO:0004535

tr|T1G9J2|T1G9J2_HELRO
Uncharacterized protein
Search

0.59	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase
0.57	GO:2001275	positive regulation of glucose import in response to insulin stimulus
0.57	GO:0090314	positive regulation of protein targeting to membrane
0.57	GO:0031340	positive regulation of vesicle fusion
0.54	GO:0072659	protein localization to plasma membrane
0.54	GO:0006906	vesicle fusion
0.50	GO:0065002	intracellular protein transmembrane transport

0.53	GO:0005544	calcium-dependent phospholipid binding
0.48	GO:0005509	calcium ion binding

0.55	GO:0032587	ruffle membrane
0.51	GO:0030659	cytoplasmic vesicle membrane
0.51	GO:0005938	cell cortex
0.51	GO:0005815	microtubule organizing center
0.47	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|T1G9J3|T1G9J3_HELRO
Uncharacterized protein
Search

XPNPEP1

0.85	X-prolyl aminopeptidase

0.61	GO:0006508	proteolysis
0.55	GO:0010815	bradykinin catabolic process
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.77	GO:0070006	metalloaminopeptidase activity
0.54	GO:0046872	metal ion binding
0.48	GO:0042803	protein homodimerization activity

0.46	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.32	GO:0005634	nucleus

tr|T1G9J4|T1G9J4_HELRO
Uncharacterized protein
Search

0.54	GO:0048675	axon extension
0.48	GO:0006468	protein phosphorylation
0.47	GO:0071340	skeletal muscle acetylcholine-gated channel clustering
0.45	GO:0001889	liver development
0.44	GO:0001835	blastocyst hatching
0.43	GO:0007566	embryo implantation
0.43	GO:0010469	regulation of receptor activity
0.42	GO:0050679	positive regulation of epithelial cell proliferation
0.41	GO:0043312	neutrophil degranulation
0.38	GO:0007165	signal transduction

0.52	GO:0004674	protein serine/threonine kinase activity
0.49	GO:0000287	magnesium ion binding
0.44	GO:0005125	cytokine activity
0.44	GO:0030554	adenyl nucleotide binding
0.43	GO:0032555	purine ribonucleotide binding
0.43	GO:0008144	drug binding
0.43	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0008083	growth factor activity
0.38	GO:0004930	G-protein coupled receptor activity
0.36	GO:0003723	RNA binding

0.62	GO:0005764	lysosome
0.59	GO:0005768	endosome
0.56	GO:0005783	endoplasmic reticulum
0.42	GO:0005615	extracellular space
0.41	GO:0034774	secretory granule lumen
0.41	GO:1903561	extracellular vesicle
0.40	GO:0005775	vacuolar lumen
0.37	GO:0005886	plasma membrane
0.37	GO:0005739	mitochondrion
0.35	GO:0045202	synapse

0.52

GO:0004674

tr|T1G9J5|T1G9J5_HELRO
Uncharacterized protein
Search

0.52	Modifier of rpr and grim ubiquitously

0.53	GO:0010099	regulation of photomorphogenesis
0.45	GO:0022900	electron transport chain
0.43	GO:0042066	perineurial glial growth
0.42	GO:0019226	transmission of nerve impulse
0.40	GO:0006836	neurotransmitter transport
0.39	GO:0000209	protein polyubiquitination
0.37	GO:0010994	free ubiquitin chain polymerization
0.37	GO:0006511	ubiquitin-dependent protein catabolic process
0.37	GO:0010458	exit from mitosis
0.37	GO:0005975	carbohydrate metabolic process

0.50	GO:0051537	2 iron, 2 sulfur cluster binding
0.47	GO:0030554	adenyl nucleotide binding
0.46	GO:0032555	purine ribonucleotide binding
0.46	GO:0008144	drug binding
0.46	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0009055	electron transfer activity
0.43	GO:0005034	osmosensor activity
0.41	GO:0016874	ligase activity
0.41	GO:0009881	photoreceptor activity
0.40	GO:0005328	neurotransmitter:sodium symporter activity

0.43	GO:0005634	nucleus
0.37	GO:0046658	anchored component of plasma membrane
0.36	GO:0031461	cullin-RING ubiquitin ligase complex
0.35	GO:0019008	molybdopterin synthase complex
0.34	GO:0005737	cytoplasm
0.34	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

0.41

EC:6

GO:0016874

tr|T1G9J6|T1G9J6_HELRO
Uncharacterized protein
Search

tr|T1G9J7|T1G9J7_HELRO
Uncharacterized protein
Search

RPS20

0.71	Ribosomal protein rps20

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.33	GO:0019083	viral transcription
0.33	GO:0016072	rRNA metabolic process
0.33	GO:0042254	ribosome biogenesis
0.33	GO:0036211	protein modification process

0.64	GO:0003735	structural constituent of ribosome
0.57	GO:0003723	RNA binding
0.34	GO:0005515	protein binding
0.33	GO:0004674	protein serine/threonine kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.70	GO:0015935	small ribosomal subunit
0.48	GO:0022626	cytosolic ribosome
0.36	GO:0031012	extracellular matrix
0.36	GO:0070062	extracellular exosome
0.33	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

0.33

GO:0004674

tr|T1G9J8|T1G9J8_HELRO
Uncharacterized protein
Search

FZR1

0.77	Fizzy and cell division cycle 20 related 1

0.83	GO:1904668	positive regulation of ubiquitin protein ligase activity
0.52	GO:0031145	anaphase-promoting complex-dependent catabolic process
0.51	GO:0072425	signal transduction involved in G2 DNA damage checkpoint
0.51	GO:0070306	lens fiber cell differentiation
0.51	GO:0090344	negative regulation of cell aging
0.50	GO:0051783	regulation of nuclear division
0.49	GO:0051445	regulation of meiotic cell cycle
0.48	GO:0045732	positive regulation of protein catabolic process
0.47	GO:0008284	positive regulation of cell proliferation
0.43	GO:0007455	eye-antennal disc morphogenesis

0.84	GO:0097027	ubiquitin-protein transferase activator activity
0.84	GO:0010997	anaphase-promoting complex binding
0.40	GO:0061630	ubiquitin protein ligase activity
0.34	GO:0004402	histone acetyltransferase activity
0.33	GO:0004721	phosphoprotein phosphatase activity
0.32	GO:0046872	metal ion binding

0.51	GO:0005680	anaphase-promoting complex
0.48	GO:0031965	nuclear membrane
0.45	GO:0005654	nucleoplasm
0.42	GO:0005814	centriole
0.41	GO:0030424	axon
0.41	GO:0005813	centrosome
0.40	GO:0005819	spindle
0.33	GO:0005829	cytosol

0.34

GO:0004402

tr|T1G9J9|T1G9J9_HELRO
Uncharacterized protein
Search

tr|T1G9K0|T1G9K0_HELRO
Uncharacterized protein
Search

0.25	Histone-lysine N-methyltransferase

0.73	GO:0034968	histone lysine methylation
0.50	GO:1901674	regulation of histone H3-K27 acetylation
0.50	GO:2001040	positive regulation of cellular response to drug
0.49	GO:0048172	regulation of short-term neuronal synaptic plasticity
0.49	GO:2001141	regulation of RNA biosynthetic process
0.49	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.49	GO:0006351	transcription, DNA-templated
0.49	GO:0043984	histone H4-K16 acetylation
0.49	GO:0071440	regulation of histone H3-K14 acetylation
0.49	GO:0010468	regulation of gene expression

0.74	GO:0018024	histone-lysine N-methyltransferase activity
0.59	GO:0008270	zinc ion binding
0.52	GO:0003677	DNA binding
0.48	GO:0070577	lysine-acetylated histone binding
0.46	GO:0003682	chromatin binding
0.46	GO:0042803	protein homodimerization activity
0.45	GO:0001067	regulatory region nucleic acid binding
0.44	GO:0003700	DNA binding transcription factor activity
0.38	GO:0008157	protein phosphatase 1 binding
0.37	GO:0004402	histone acetyltransferase activity

0.63	GO:0044665	MLL1/2 complex
0.43	GO:0005829	cytosol
0.38	GO:0005700	polytene chromosome
0.37	GO:0008023	transcription elongation factor complex
0.37	GO:0000123	histone acetyltransferase complex
0.34	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
0.34	GO:0000151	ubiquitin ligase complex
0.30	GO:0016021	integral component of membrane

0.74

EC:2.1.1.43

GO:0018024

tr|T1G9K1|T1G9K1_HELRO
Uncharacterized protein
Search

0.59	GO:0035050	embryonic heart tube development
0.58	GO:0006351	transcription, DNA-templated
0.58	GO:0060577	pulmonary vein morphogenesis
0.58	GO:0035922	foramen ovale closure
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:0003180	aortic valve morphogenesis
0.57	GO:0003193	pulmonary valve formation
0.56	GO:0010468	regulation of gene expression
0.56	GO:0021524	visceral motor neuron differentiation

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.54	GO:0001105	RNA polymerase II transcription coactivator activity
0.53	GO:0001102	RNA polymerase II activating transcription factor binding
0.50	GO:0001067	regulatory region nucleic acid binding
0.35	GO:0001226	RNA polymerase II transcription corepressor binding

0.61	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1G9K2|T1G9K2_HELRO
Uncharacterized protein
Search

CARS

0.43	Cysteinyl-trna cytoplasmic

0.78

GO:0006423

cysteinyl-tRNA aminoacylation

0.79	GO:0004817	cysteine-tRNA ligase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0042803	protein homodimerization activity
0.42	GO:0000049	tRNA binding
0.34	GO:0046872	metal ion binding

0.41	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.79

EC:6.1.1.16

GO:0004817

tr|T1G9K3|T1G9K3_HELRO
Uncharacterized protein
Search

0.74	Hyperpolarization-activated cyclic nucleotide-modulated cation channel splice variant ABs-II

0.69	GO:0071805	potassium ion transmembrane transport
0.61	GO:0043269	regulation of ion transport
0.60	GO:0034762	regulation of transmembrane transport
0.46	GO:0016057	regulation of membrane potential in photoreceptor cell
0.46	GO:0007637	proboscis extension reflex
0.46	GO:0071632	optomotor response
0.46	GO:0050802	circadian sleep/wake cycle, sleep
0.45	GO:0071484	cellular response to light intensity
0.45	GO:0045938	positive regulation of circadian sleep/wake cycle, sleep
0.44	GO:0050433	regulation of catecholamine secretion

0.73	GO:0005249	voltage-gated potassium channel activity
0.35	GO:0004692	cGMP-dependent protein kinase activity
0.33	GO:0003677	DNA binding

0.36	GO:0005887	integral component of plasma membrane
0.33	GO:0005634	nucleus

0.35

EC:2.7.11.12

GO:0004692

tr|T1G9K4|T1G9K4_HELRO
Uncharacterized protein
Search

0.71	Pyruvate dehyrogenase phosphatase catalytic subunit 1

0.72	GO:0006470	protein dephosphorylation
0.48	GO:1904184	positive regulation of pyruvate dehydrogenase activity
0.36	GO:0010826	negative regulation of centrosome duplication
0.35	GO:0060271	cilium assembly
0.33	GO:0006730	one-carbon metabolic process
0.33	GO:1904359	regulation of spore germination
0.33	GO:0006090	pyruvate metabolic process
0.32	GO:0006468	protein phosphorylation

0.76	GO:0004722	protein serine/threonine phosphatase activity
0.50	GO:0046872	metal ion binding
0.48	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity
0.34	GO:0004089	carbonate dehydratase activity
0.32	GO:0003924	GTPase activity
0.32	GO:0001883	purine nucleoside binding
0.32	GO:0019001	guanyl nucleotide binding
0.32	GO:0032549	ribonucleoside binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.47	GO:0005967	mitochondrial pyruvate dehydrogenase complex
0.45	GO:0005758	mitochondrial intermembrane space
0.36	GO:0005634	nucleus
0.36	GO:0036038	MKS complex
0.30	GO:0016021	integral component of membrane

0.48

EC:3.1.3.43

GO:0004741

tr|T1G9K5|T1G9K5_HELRO
Uncharacterized protein
Search

0.63	Bone morphogenetic protein 2

0.75	GO:0010469	regulation of receptor activity
0.57	GO:0060063	Spemann organizer formation at the embryonic shield
0.55	GO:0048264	determination of ventral identity
0.47	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
0.45	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
0.44	GO:0042981	regulation of apoptotic process
0.43	GO:0042701	progesterone secretion
0.43	GO:0046880	regulation of follicle-stimulating hormone secretion
0.43	GO:0030154	cell differentiation
0.42	GO:0042541	hemoglobin biosynthetic process

0.78	GO:0008083	growth factor activity
0.60	GO:0005179	hormone activity
0.45	GO:0005125	cytokine activity
0.44	GO:0005160	transforming growth factor beta receptor binding
0.41	GO:0070699	type II activin receptor binding
0.40	GO:0017046	peptide hormone binding
0.38	GO:0042802	identical protein binding

0.66	GO:0005576	extracellular region
0.38	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0043234	protein complex
0.33	GO:0031982	vesicle
0.33	GO:0005634	nucleus

tr|T1G9K6|T1G9K6_HELRO
Uncharacterized protein
Search

SH3GL1

0.86	Endophilin-A

0.71	GO:0006897	endocytosis
0.44	GO:0072318	clathrin coat disassembly
0.43	GO:0036465	synaptic vesicle recycling
0.42	GO:0099003	vesicle-mediated transport in synapse
0.41	GO:0010940	positive regulation of necrotic cell death
0.35	GO:0006383	transcription by RNA polymerase III
0.35	GO:1900242	regulation of synaptic vesicle endocytosis
0.34	GO:0098815	modulation of excitatory postsynaptic potential
0.34	GO:0007417	central nervous system development
0.33	GO:0012501	programmed cell death

0.42	GO:0045296	cadherin binding
0.41	GO:0042802	identical protein binding
0.39	GO:0016746	transferase activity, transferring acyl groups
0.35	GO:0031697	beta-1 adrenergic receptor binding
0.34	GO:0008289	lipid binding
0.34	GO:0044325	ion channel binding
0.34	GO:0008022	protein C-terminus binding
0.34	GO:0019902	phosphatase binding
0.34	GO:0017124	SH3 domain binding
0.33	GO:0051020	GTPase binding

0.49	GO:0005737	cytoplasm
0.43	GO:0045202	synapse
0.36	GO:0002102	podosome
0.36	GO:0005666	DNA-directed RNA polymerase III complex
0.35	GO:0030054	cell junction
0.35	GO:0097708	intracellular vesicle
0.35	GO:0012505	endomembrane system
0.34	GO:0098805	whole membrane
0.34	GO:0098588	bounding membrane of organelle
0.34	GO:0042995	cell projection

0.39

EC:2.3

GO:0016746

tr|T1G9K7|T1G9K7_HELRO
Uncharacterized protein
Search

tr|T1G9K8|T1G9K8_HELRO
Uncharacterized protein
Search

0.57	Acidic ribosomal protein P2

0.69	GO:0006414	translational elongation
0.42	GO:0002181	cytoplasmic translation
0.37	GO:0009409	response to cold

0.63

GO:0003735

structural constituent of ribosome

0.61	GO:0005840	ribosome
0.41	GO:0044445	cytosolic part
0.37	GO:0005844	polysome
0.37	GO:0044446	intracellular organelle part
0.36	GO:0005794	Golgi apparatus
0.34	GO:0005634	nucleus
0.34	GO:0070013	intracellular organelle lumen
0.34	GO:0009507	chloroplast
0.33	GO:0005886	plasma membrane

tr|T1G9K9|T1G9K9_HELRO
Uncharacterized protein
Search

0.41	Adenylate cyclase type 9 (inferred by orthology to a human protein)

0.76	GO:0009190	cyclic nucleotide biosynthetic process
0.63	GO:0035556	intracellular signal transduction
0.42	GO:2000292	regulation of defecation
0.41	GO:0072375	medium-term memory
0.41	GO:0046058	cAMP metabolic process
0.41	GO:0043547	positive regulation of GTPase activity
0.41	GO:0007614	short-term memory
0.41	GO:0030431	sleep
0.40	GO:0002119	nematode larval development
0.40	GO:0009152	purine ribonucleotide biosynthetic process

0.75	GO:0016849	phosphorus-oxygen lyase activity
0.48	GO:1901265	nucleoside phosphate binding
0.47	GO:0036094	small molecule binding
0.43	GO:0009975	cyclase activity
0.41	GO:0005096	GTPase activator activity
0.33	GO:0046982	protein heterodimerization activity
0.32	GO:0046872	metal ion binding

0.45	GO:0005622	intracellular
0.36	GO:0005886	plasma membrane
0.35	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.75

EC:4.6

GO:0016849

tr|T1G9L0|T1G9L0_HELRO
Uncharacterized protein
Search

STK38

0.54	Serine/threonine-protein kinase tricorner

0.63	GO:0006468	protein phosphorylation
0.48	GO:0043407	negative regulation of MAP kinase activity
0.48	GO:0018209	peptidyl-serine modification
0.47	GO:0035556	intracellular signal transduction
0.42	GO:0051128	regulation of cellular component organization
0.33	GO:0010467	gene expression
0.33	GO:0009059	macromolecule biosynthetic process
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.70	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0031435	mitogen-activated protein kinase kinase kinase binding
0.47	GO:0045296	cadherin binding
0.46	GO:0000287	magnesium ion binding
0.33	GO:0003779	actin binding
0.33	GO:0046983	protein dimerization activity
0.33	GO:0003735	structural constituent of ribosome

0.48	GO:0005829	cytosol
0.44	GO:0015629	actin cytoskeleton
0.41	GO:0005634	nucleus
0.33	GO:0005667	transcription factor complex
0.33	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.70

GO:0004674

tr|T1G9L1|T1G9L1_HELRO
Uncharacterized protein
Search

tr|T1G9L2|T1G9L2_HELRO
Uncharacterized protein
Search

0.72	GO:0008154	actin polymerization or depolymerization
0.71	GO:0051289	protein homotetramerization
0.71	GO:0044089	positive regulation of cellular component biogenesis
0.70	GO:0032956	regulation of actin cytoskeleton organization
0.68	GO:1902905	positive regulation of supramolecular fiber organization
0.68	GO:0051495	positive regulation of cytoskeleton organization
0.68	GO:0032271	regulation of protein polymerization
0.67	GO:0032535	regulation of cellular component size
0.56	GO:0120032	regulation of plasma membrane bounded cell projection assembly
0.54	GO:0007396	suture of dorsal opening

0.71	GO:0017124	SH3 domain binding
0.63	GO:0003779	actin binding
0.50	GO:0005522	profilin binding
0.38	GO:0033897	ribonuclease T2 activity
0.35	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
0.35	GO:0003676	nucleic acid binding
0.34	GO:0003700	DNA binding transcription factor activity

0.59	GO:0005856	cytoskeleton
0.55	GO:0030027	lamellipodium
0.54	GO:0005912	adherens junction
0.52	GO:0071212	subsynaptic reticulum
0.51	GO:0032433	filopodium tip
0.48	GO:0030425	dendrite
0.48	GO:0045335	phagocytic vesicle
0.47	GO:0030055	cell-substrate junction
0.46	GO:0005911	cell-cell junction
0.44	GO:0005829	cytosol

0.38

EC:3.1.27.1

GO:0033897

tr|T1G9L3|T1G9L3_HELRO
Uncharacterized protein
Search

PRPF3

0.86	Pre-mRNA-processing factor 3

0.75	GO:0000398	mRNA splicing, via spliceosome
0.47	GO:0022618	ribonucleoprotein complex assembly
0.46	GO:0031935	regulation of chromatin silencing
0.38	GO:0060041	retina development in camera-type eye
0.36	GO:0006979	response to oxidative stress
0.36	GO:0098869	cellular oxidant detoxification
0.34	GO:0055114	oxidation-reduction process
0.33	GO:0043043	peptide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0009059	macromolecule biosynthetic process

0.46	GO:0042802	identical protein binding
0.36	GO:0004601	peroxidase activity
0.35	GO:0020037	heme binding
0.35	GO:0003723	RNA binding
0.33	GO:0003735	structural constituent of ribosome
0.33	GO:0008270	zinc ion binding

0.81	GO:0046540	U4/U6 x U5 tri-snRNP complex
0.57	GO:0019013	viral nucleocapsid
0.51	GO:0015030	Cajal body
0.49	GO:0016607	nuclear speck
0.44	GO:0005829	cytosol
0.39	GO:0005681	spliceosomal complex
0.34	GO:0043234	protein complex
0.33	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.36	EC:1.11.1.7	GO:0004601
0.36	KEGG:R03532	GO:0004601

tr|T1G9L4|T1G9L4_HELRO
Innexin
Search

INX

0.42

Innexin

0.58	GO:0006811	ion transport
0.38	GO:0010644	cell communication by electrical coupling
0.34	GO:0007630	jump response
0.34	GO:0016264	gap junction assembly
0.34	GO:0010496	intercellular transport
0.34	GO:0003254	regulation of membrane depolarization
0.34	GO:0055085	transmembrane transport
0.33	GO:0007602	phototransduction
0.33	GO:0007186	G-protein coupled receptor signaling pathway
0.32	GO:0006518	peptide metabolic process

0.38	GO:0005243	gap junction channel activity
0.33	GO:0009881	photoreceptor activity
0.33	GO:0004930	G-protein coupled receptor activity
0.32	GO:0003735	structural constituent of ribosome
0.30	GO:0003824	catalytic activity

0.80	GO:0005921	gap junction
0.55	GO:0005886	plasma membrane
0.35	GO:0045202	synapse
0.33	GO:0005856	cytoskeleton
0.32	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

tr|T1G9L5|T1G9L5_HELRO
Uncharacterized protein
Search

0.57	Cystathionine beta-synthase

0.83	GO:0019343	cysteine biosynthetic process via cystathionine
0.76	GO:0006535	cysteine biosynthetic process from serine
0.40	GO:0019346	transsulfuration
0.39	GO:0007089	traversing start control point of mitotic cell cycle
0.37	GO:0070813	hydrogen sulfide metabolic process
0.37	GO:0009403	toxin biosynthetic process
0.35	GO:0000302	response to reactive oxygen species
0.35	GO:0007186	G-protein coupled receptor signaling pathway
0.34	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.34	GO:0019280	L-methionine biosynthetic process from homoserine via O-acetyl-L-homoserine and cystathionine

0.83	GO:0004122	cystathionine beta-synthase activity
0.38	GO:0030170	pyridoxal phosphate binding
0.35	GO:0008528	G-protein coupled peptide receptor activity
0.35	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.34	GO:0004124	cysteine synthase activity
0.33	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.33	GO:0020037	heme binding
0.33	GO:0003676	nucleic acid binding

0.48	GO:0005737	cytoplasm
0.38	GO:0035770	ribonucleoprotein granule
0.30	GO:0016020	membrane

0.83

EC:4.2.1.22

GO:0004122

tr|T1G9L6|T1G9L6_HELRO
Uncharacterized protein
Search

GALC

0.91	galactocerebrosidase precursor

0.86	GO:0006683	galactosylceramide catabolic process
0.36	GO:0045493	xylan catabolic process
0.34	GO:0045859	regulation of protein kinase activity

0.86	GO:0004336	galactosylceramidase activity
0.36	GO:0031176	endo-1,4-beta-xylanase activity
0.34	GO:0008081	phosphoric diester hydrolase activity
0.34	GO:0019887	protein kinase regulator activity
0.33	GO:0046556	alpha-L-arabinofuranosidase activity
0.33	GO:0030246	carbohydrate binding

0.43	GO:0005764	lysosome
0.39	GO:0005739	mitochondrion
0.36	GO:0070062	extracellular exosome
0.34	GO:0005956	protein kinase CK2 complex
0.30	GO:0016020	membrane

0.86

EC:3.2.1.46

GO:0004336

tr|T1G9L7|T1G9L7_HELRO
Uncharacterized protein
Search

tr|T1G9L8|T1G9L8_HELRO
Uncharacterized protein
Search

0.74	Nephrocystin-4

0.84	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.54	GO:1903348	positive regulation of bicellular tight junction assembly
0.52	GO:0035845	photoreceptor cell outer segment organization
0.51	GO:0045494	photoreceptor cell maintenance
0.51	GO:0030317	flagellated sperm motility
0.50	GO:0048513	animal organ development
0.46	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway
0.46	GO:0035844	cloaca development
0.46	GO:0071907	determination of digestive tract left/right asymmetry
0.46	GO:0060028	convergent extension involved in axis elongation

0.35	GO:0005515	protein binding
0.33	GO:0008375	acetylglucosaminyltransferase activity
0.33	GO:0009982	pseudouridine synthase activity
0.32	GO:0003723	RNA binding
0.32	GO:0004540	ribonuclease activity

0.83	GO:0097730	non-motile cilium
0.69	GO:0005856	cytoskeleton
0.53	GO:0097470	ribbon synapse
0.51	GO:0097546	ciliary base
0.50	GO:0035869	ciliary transition zone
0.48	GO:0043005	neuron projection
0.47	GO:0005911	cell-cell junction
0.40	GO:0044446	intracellular organelle part
0.37	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0008375

tr|T1G9L9|T1G9L9_HELRO
Uncharacterized protein
Search

0.58	Store-operated calcium entry-associated regulatory factor

0.85	GO:2001256	regulation of store-operated calcium entry
0.35	GO:0006816	calcium ion transport
0.33	GO:0006259	DNA metabolic process

0.35	GO:0004531	deoxyribonuclease II activity
0.34	GO:0005509	calcium ion binding

0.78

GO:0030176

integral component of endoplasmic reticulum membrane

0.35

EC:3.1.22.1

GO:0004531

tr|T1G9M0|T1G9M0_HELRO
Uncharacterized protein
Search

0.87	Cysteine N-palmitoyltransferase porcupine

0.41	GO:0061355	Wnt protein secretion
0.39	GO:0018345	protein palmitoylation
0.38	GO:0030111	regulation of Wnt signaling pathway
0.38	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation
0.37	GO:0007369	gastrulation
0.37	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.36	GO:0060069	Wnt signaling pathway, regulating spindle positioning
0.36	GO:0051604	protein maturation
0.36	GO:0045167	asymmetric protein localization involved in cell fate determination
0.36	GO:0009888	tissue development

0.43	GO:0016740	transferase activity
0.39	GO:0017147	Wnt-protein binding
0.39	GO:0000213	tRNA-intron endonuclease activity
0.36	GO:0005509	calcium ion binding
0.34	GO:0003676	nucleic acid binding

0.37	GO:0005783	endoplasmic reticulum
0.35	GO:0005634	nucleus
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.43

EC:2

GO:0016740

tr|T1G9M1|T1G9M1_HELRO
Uncharacterized protein
Search

0.55	Tropomyosin-1, isoforms 9A/A/B

0.56	GO:0007094	mitotic spindle assembly checkpoint
0.52	GO:0006260	DNA replication
0.47	GO:0006351	transcription, DNA-templated
0.46	GO:1903506	regulation of nucleic acid-templated transcription
0.46	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.46	GO:0000724	double-strand break repair via homologous recombination
0.46	GO:0010468	regulation of gene expression

0.49	GO:0003700	DNA binding transcription factor activity
0.45	GO:0003677	DNA binding
0.38	GO:0046872	metal ion binding

0.50	GO:0005815	microtubule organizing center
0.49	GO:0005634	nucleus
0.47	GO:0030915	Smc5-Smc6 complex

tr|T1G9M2|T1G9M2_HELRO
Uncharacterized protein
Search

0.38	Transcription factor

0.57	GO:0006351	transcription, DNA-templated
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0060842	arterial endothelial cell differentiation
0.55	GO:0035912	dorsal aorta morphogenesis
0.54	GO:0061027	umbilical cord development
0.54	GO:0003195	tricuspid valve formation
0.54	GO:0060948	cardiac vascular smooth muscle cell development
0.54	GO:0035910	ascending aorta morphogenesis

0.68	GO:0046983	protein dimerization activity
0.54	GO:0003677	DNA binding
0.52	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding
0.51	GO:0001102	RNA polymerase II activating transcription factor binding
0.50	GO:0042826	histone deacetylase binding
0.47	GO:0000989	transcription factor activity, transcription factor binding
0.47	GO:0042802	identical protein binding
0.35	GO:0050683	AF-1 domain binding
0.34	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.33	GO:0004075	biotin carboxylase activity

0.61	GO:0005634	nucleus
0.49	GO:0017053	transcriptional repressor complex
0.46	GO:0000785	chromatin
0.44	GO:0070013	intracellular organelle lumen
0.42	GO:1902494	catalytic complex
0.37	GO:0005737	cytoplasm
0.35	GO:0005667	transcription factor complex
0.30	GO:0016021	integral component of membrane

0.33

EC:6.3.4.14

GO:0004075

tr|T1G9M3|T1G9M3_HELRO
DNA-directed RNA polymerase subunit beta
Search

POLR3B

0.41	DNA-directed RNA polymerase subunit beta

0.58	GO:0006351	transcription, DNA-templated
0.54	GO:0032728	positive regulation of interferon-beta production
0.51	GO:0045089	positive regulation of innate immune response
0.45	GO:0031017	exocrine pancreas development
0.43	GO:0048565	digestive tract development
0.40	GO:0006399	tRNA metabolic process
0.35	GO:0045087	innate immune response
0.35	GO:0051607	defense response to virus
0.34	GO:0031167	rRNA methylation
0.32	GO:2001141	regulation of RNA biosynthetic process

0.70	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.65	GO:0001882	nucleoside binding
0.55	GO:0003677	DNA binding
0.34	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity
0.33	GO:0046872	metal ion binding
0.33	GO:0003723	RNA binding

0.55	GO:0005666	DNA-directed RNA polymerase III complex
0.33	GO:0005829	cytosol

0.70

EC:2.7.7.6

GO:0003899

tr|T1G9M4|T1G9M4_HELRO
Uncharacterized protein
Search

ATIC

0.44	Bifunctional purine biosynthesis protein PURH

0.66	GO:0006164	purine nucleotide biosynthetic process
0.43	GO:0046040	IMP metabolic process
0.42	GO:0009168	purine ribonucleoside monophosphate biosynthetic process
0.41	GO:0009260	ribonucleotide biosynthetic process
0.37	GO:0003360	brainstem development
0.37	GO:0030437	ascospore formation
0.37	GO:0042060	wound healing
0.36	GO:0031100	animal organ regeneration
0.36	GO:0046452	dihydrofolate metabolic process
0.36	GO:0021549	cerebellum development

0.79	GO:0004643	phosphoribosylaminoimidazolecarboxamide formyltransferase activity
0.79	GO:0003937	IMP cyclohydrolase activity
0.49	GO:0045296	cadherin binding
0.47	GO:0042803	protein homodimerization activity

0.46	GO:0005829	cytosol
0.41	GO:0005739	mitochondrion
0.40	GO:0005886	plasma membrane
0.34	GO:0070062	extracellular exosome

0.79

EC:2.1.2.3

GO:0004643

tr|T1G9M5|T1G9M5_HELRO
RNA helicase
Search

0.49	probable ATP-dependent RNA helicase pitchoune

0.44	GO:0016049	cell growth
0.44	GO:0008283	cell proliferation
0.41	GO:0010501	RNA secondary structure unwinding
0.40	GO:0030099	myeloid cell differentiation
0.38	GO:1990417	snoRNA release from pre-rRNA
0.37	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.37	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

0.67	GO:0004386	helicase activity
0.58	GO:0003723	RNA binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0008186	RNA-dependent ATPase activity
0.38	GO:0140098	catalytic activity, acting on RNA
0.36	GO:0042802	identical protein binding
0.33	GO:0016779	nucleotidyltransferase activity

0.45	GO:0005730	nucleolus
0.37	GO:0072588	box H/ACA RNP complex
0.36	GO:0030687	preribosome, large subunit precursor
0.36	GO:0005635	nuclear envelope
0.34	GO:1902494	catalytic complex
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:2.7.7

GO:0016779

tr|T1G9M6|T1G9M6_HELRO
Uncharacterized protein
Search

EIF4A3

0.60	DEAD box ATP-dependent RNA helicase

0.57	GO:0006413	translational initiation
0.49	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.47	GO:0048701	embryonic cranial skeleton morphogenesis
0.46	GO:0006417	regulation of translation
0.46	GO:0010501	RNA secondary structure unwinding
0.45	GO:0008380	RNA splicing
0.45	GO:0034249	negative regulation of cellular amide metabolic process
0.45	GO:0034250	positive regulation of cellular amide metabolic process
0.44	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.43	GO:0032270	positive regulation of cellular protein metabolic process

0.64	GO:0004386	helicase activity
0.58	GO:0003743	translation initiation factor activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0008186	RNA-dependent ATPase activity
0.47	GO:0008143	poly(A) binding
0.44	GO:0003729	mRNA binding
0.42	GO:0140098	catalytic activity, acting on RNA

0.49	GO:0071013	catalytic step 2 spliceosome
0.47	GO:0035145	exon-exon junction complex
0.46	GO:0031981	nuclear lumen
0.39	GO:0043232	intracellular non-membrane-bounded organelle
0.38	GO:0005737	cytoplasm
0.37	GO:0043025	neuronal cell body
0.37	GO:0030425	dendrite
0.30	GO:0016020	membrane

0.33

GO:0008168

tr|T1G9M7|T1G9M7_HELRO
Uncharacterized protein
Search

SLC30A5

0.86	Solute carrier family 30 (Zinc transporter), member 5

0.69	GO:0010043	response to zinc ion
0.62	GO:0006882	cellular zinc ion homeostasis
0.61	GO:0098655	cation transmembrane transport
0.59	GO:0006829	zinc II ion transport
0.58	GO:0006824	cobalt ion transport
0.48	GO:0098660	inorganic ion transmembrane transport
0.47	GO:0061088	regulation of sequestering of zinc ion

0.61	GO:0008324	cation transmembrane transporter activity
0.48	GO:0015318	inorganic molecular entity transmembrane transporter activity

0.59	GO:0016324	apical plasma membrane
0.59	GO:0030141	secretory granule
0.54	GO:0005730	nucleolus
0.54	GO:0005794	Golgi apparatus
0.30	GO:0031224	intrinsic component of membrane

tr|T1G9M8|T1G9M8_HELRO
Ubiquitin-related modifier 1 homolog
Search

URM1

0.73	Ubiquitin-related modifier 1 homolog

0.79	GO:0032447	protein urmylation
0.79	GO:0034227	tRNA thio-modification
0.72	GO:0002098	tRNA wobble uridine modification
0.43	GO:0001403	invasive growth in response to glucose limitation
0.42	GO:0007114	cell budding
0.41	GO:0046329	negative regulation of JNK cascade
0.40	GO:0034599	cellular response to oxidative stress
0.34	GO:0002128	tRNA nucleoside ribose methylation
0.34	GO:0002181	cytoplasmic translation
0.32	GO:0006281	DNA repair

0.45	GO:0016783	sulfurtransferase activity
0.42	GO:0031386	protein tag
0.40	GO:0042803	protein homodimerization activity
0.33	GO:0008175	tRNA methyltransferase activity
0.32	GO:0008081	phosphoric diester hydrolase activity

0.64	GO:0005829	cytosol
0.35	GO:0070062	extracellular exosome
0.32	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.45

EC:2.8.1

GO:0016783

tr|T1G9M9|T1G9M9_HELRO
Uncharacterized protein
Search

tr|T1G9N0|T1G9N0_HELRO
Serine/threonine-protein phosphatase
Search

0.52	Serine/threonine-protein phosphatase

0.71	GO:0006470	protein dephosphorylation
0.40	GO:0007098	centrosome cycle
0.40	GO:0018985	pronuclear envelope synthesis
0.40	GO:0007051	spindle organization
0.39	GO:0000278	mitotic cell cycle
0.39	GO:0031468	nuclear envelope reassembly
0.38	GO:0007465	R7 cell fate commitment
0.38	GO:0008637	apoptotic mitochondrial changes
0.38	GO:1903008	organelle disassembly
0.38	GO:0007406	negative regulation of neuroblast proliferation

0.72	GO:0004721	phosphoprotein phosphatase activity
0.39	GO:0017151	DEAD/H-box RNA helicase binding
0.36	GO:0019208	phosphatase regulator activity
0.34	GO:0046982	protein heterodimerization activity
0.33	GO:0046872	metal ion binding

0.42	GO:0000159	protein phosphatase type 2A complex
0.39	GO:0005815	microtubule organizing center
0.39	GO:0044295	axonal growth cone
0.38	GO:0043025	neuronal cell body
0.35	GO:0005737	cytoplasm
0.33	GO:0005654	nucleoplasm

0.72

GO:0004721

tr|T1G9N1|T1G9N1_HELRO
Uncharacterized protein
Search

0.11

Pygopus

0.48	GO:0048526	imaginal disc-derived wing expansion
0.47	GO:0035293	chitin-based larval cuticle pattern formation
0.47	GO:0060232	delamination
0.47	GO:0007367	segment polarity determination
0.46	GO:0035214	eye-antennal disc development
0.45	GO:0030177	positive regulation of Wnt signaling pathway
0.45	GO:0060070	canonical Wnt signaling pathway
0.43	GO:0006366	transcription by RNA polymerase II
0.43	GO:0045944	positive regulation of transcription by RNA polymerase II
0.37	GO:0006338	chromatin remodeling

0.52	GO:0046872	metal ion binding
0.46	GO:0001105	RNA polymerase II transcription coactivator activity
0.45	GO:0140034	methylation-dependent protein binding
0.44	GO:0042393	histone binding
0.36	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.35	GO:0003677	DNA binding
0.34	GO:0022857	transmembrane transporter activity
0.33	GO:0003723	RNA binding
0.33	GO:0016887	ATPase activity
0.33	GO:0004386	helicase activity

0.47	GO:1990907	beta-catenin-TCF complex
0.37	GO:0070603	SWI/SNF superfamily-type complex
0.34	GO:0005581	collagen trimer
0.34	GO:0005654	nucleoplasm
0.33	GO:0005685	U1 snRNP
0.32	GO:0019013	viral nucleocapsid
0.30	GO:0016020	membrane

0.36

EC:2.7.7.6

GO:0003899

tr|T1G9N2|T1G9N2_HELRO
Uncharacterized protein
Search

0.42	Alpha-N-acetylgalactosaminidase

0.60

GO:0005975

carbohydrate metabolic process

0.66	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.38	GO:0042803	protein homodimerization activity
0.38	GO:0005102	receptor binding
0.34	GO:0005509	calcium ion binding

0.39	GO:0005764	lysosome
0.38	GO:0005794	Golgi apparatus
0.37	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.66

EC:3.2.1

GO:0004553

tr|T1G9N3|T1G9N3_HELRO
Uncharacterized protein
Search

HSD17B4

0.84	Peroxisomal multifunctional enzyme type 2

0.54	GO:0036111	very long-chain fatty-acyl-CoA metabolic process
0.53	GO:0036112	medium-chain fatty-acyl-CoA metabolic process
0.52	GO:0055114	oxidation-reduction process
0.52	GO:0008209	androgen metabolic process
0.52	GO:0008210	estrogen metabolic process
0.51	GO:0060009	Sertoli cell development
0.49	GO:0000038	very long-chain fatty acid metabolic process
0.47	GO:0009062	fatty acid catabolic process
0.46	GO:0030258	lipid modification
0.43	GO:0048568	embryonic organ development

0.54	GO:0044594	17-beta-hydroxysteroid dehydrogenase (NAD+) activity
0.54	GO:0016508	long-chain-enoyl-CoA hydratase activity
0.48	GO:0042803	protein homodimerization activity
0.47	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity
0.45	GO:0005102	receptor binding
0.42	GO:0033989	3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity
0.41	GO:0080023	3R-hydroxyacyl-CoA dehydratase activity
0.39	GO:0004300	enoyl-CoA hydratase activity
0.35	GO:0030283	testosterone dehydrogenase [NAD(P)] activity
0.35	GO:0004674	protein serine/threonine kinase activity

0.47	GO:0005777	peroxisome
0.41	GO:0005739	mitochondrion
0.36	GO:0031903	microbody membrane
0.35	GO:0031907	microbody lumen
0.30	GO:0031224	intrinsic component of membrane

0.54

EC:4.2.1.74

GO:0016508

tr|T1G9N4|T1G9N4_HELRO
Uncharacterized protein
Search

0.11	Angiotensin-converting enzyme

0.61	GO:0006508	proteolysis
0.37	GO:0060319	primitive erythrocyte differentiation
0.36	GO:0008283	cell proliferation

0.84	GO:0008241	peptidyl-dipeptidase activity
0.67	GO:0008237	metallopeptidase activity
0.66	GO:0004180	carboxypeptidase activity
0.50	GO:0046872	metal ion binding
0.36	GO:0008239	dipeptidyl-peptidase activity

0.30

GO:0031224

intrinsic component of membrane

0.84

EC:3.4.15

GO:0008241

tr|T1G9N5|T1G9N5_HELRO
Uncharacterized protein
Search

0.49	RING finger protein 112 (inferred by orthology to a human protein)

0.44	GO:0048687	positive regulation of sprouting of injured axon
0.44	GO:0048690	regulation of axon extension involved in regeneration
0.44	GO:0016320	endoplasmic reticulum membrane fusion
0.43	GO:0051124	synaptic growth at neuromuscular junction
0.43	GO:0007019	microtubule depolymerization
0.43	GO:0007029	endoplasmic reticulum organization
0.43	GO:0007030	Golgi organization
0.43	GO:0045773	positive regulation of axon extension
0.43	GO:0031114	regulation of microtubule depolymerization
0.43	GO:0008582	regulation of synaptic growth at neuromuscular junction

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0042802	identical protein binding
0.39	GO:0046983	protein dimerization activity
0.36	GO:0008479	queuine tRNA-ribosyltransferase activity

0.41	GO:0031227	intrinsic component of endoplasmic reticulum membrane
0.40	GO:0005874	microtubule
0.39	GO:0005794	Golgi apparatus
0.37	GO:0098826	endoplasmic reticulum tubular network membrane
0.33	GO:0098588	bounding membrane of organelle
0.30	GO:0016021	integral component of membrane

0.36

EC:2.4.2.29

GO:0008479

tr|T1G9N6|T1G9N6_HELRO
Uncharacterized protein
Search

BCKDHB

0.94	Branched chain keto acid dehydrogenase E1 beta polypeptide

0.61	GO:0009083	branched-chain amino acid catabolic process
0.43	GO:0055114	oxidation-reduction process

0.61	GO:0003826	alpha-ketoacid dehydrogenase activity
0.37	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity

0.66

GO:0005947

mitochondrial alpha-ketoglutarate dehydrogenase complex

0.37

EC:1.2.4.1

GO:0004739

tr|T1G9N7|T1G9N7_HELRO
Uncharacterized protein
Search

0.75	Cofilin/actin-depolymerizing factor

0.74

GO:0003779

actin binding

0.45

GO:0005622

intracellular

tr|T1G9N8|T1G9N8_HELRO
Uncharacterized protein
Search

0.60	GO:0021527	spinal cord association neuron differentiation
0.57	GO:0048663	neuron fate commitment
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0030900	forebrain development
0.52	GO:0048714	positive regulation of oligodendrocyte differentiation
0.52	GO:0002087	regulation of respiratory gaseous exchange by neurological system process
0.50	GO:0048854	brain morphogenesis
0.50	GO:0021575	hindbrain morphogenesis

0.65	GO:0043565	sequence-specific DNA binding
0.48	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.46	GO:0001012	RNA polymerase II regulatory region DNA binding
0.44	GO:0003690	double-stranded DNA binding
0.40	GO:0008134	transcription factor binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0032561	guanyl ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005634	nucleus
0.33	GO:0005874	microtubule
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016020	membrane

tr|T1G9N9|T1G9N9_HELRO
Uncharacterized protein
Search

0.63	Trimeric intracellular cation channel type B

0.62	GO:0015672	monovalent inorganic cation transport
0.61	GO:0098655	cation transmembrane transport
0.44	GO:0030001	metal ion transport
0.42	GO:0098660	inorganic ion transmembrane transport
0.30	GO:0009987	cellular process

0.74	GO:0005261	cation channel activity
0.46	GO:0015079	potassium ion transmembrane transporter activity
0.46	GO:0022839	ion gated channel activity
0.46	GO:0008381	mechanosensitive ion channel activity

0.46	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

tr|T1G9P0|T1G9P0_HELRO
Uncharacterized protein
Search

tr|T1G9P1|T1G9P1_HELRO
Uncharacterized protein
Search

STT3A

0.86	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A

0.74	GO:0043413	macromolecule glycosylation
0.74	GO:0009101	glycoprotein biosynthetic process
0.60	GO:0006464	cellular protein modification process

0.83	GO:0004576	oligosaccharyl transferase activity
0.34	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding
0.32	GO:0003723	RNA binding

0.47	GO:0008250	oligosaccharyltransferase complex
0.30	GO:0031224	intrinsic component of membrane

0.83

GO:0004576

tr|T1G9P2|T1G9P2_HELRO
Uncharacterized protein
Search

TCEA1

0.90	Transcription elongation factor A protein 1

0.58	GO:0006414	translational elongation
0.57	GO:0006351	transcription, DNA-templated
0.54	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.39	GO:1901919	positive regulation of exoribonuclease activity
0.35	GO:1902680	positive regulation of RNA biosynthetic process
0.35	GO:0030218	erythrocyte differentiation
0.34	GO:0006283	transcription-coupled nucleotide-excision repair

0.61	GO:0008270	zinc ion binding
0.59	GO:0003746	translation elongation factor activity
0.35	GO:0003677	DNA binding
0.35	GO:0005515	protein binding
0.32	GO:0016787	hydrolase activity

0.59	GO:0005634	nucleus
0.47	GO:0000428	DNA-directed RNA polymerase complex
0.47	GO:0005667	transcription factor complex
0.45	GO:0031974	membrane-enclosed lumen
0.41	GO:0043232	intracellular non-membrane-bounded organelle
0.41	GO:0044446	intracellular organelle part

0.32

GO:0016787

tr|T1G9P3|T1G9P3_HELRO
Uncharacterized protein
Search

PPP2R5D

0.60	Serine/threonine protein phosphatase 2A regulatory subunit

0.79	GO:0043666	regulation of phosphoprotein phosphatase activity
0.61	GO:0007165	signal transduction
0.48	GO:0035307	positive regulation of protein dephosphorylation
0.43	GO:0006470	protein dephosphorylation
0.42	GO:1903863	P granule assembly
0.38	GO:0070328	triglyceride homeostasis
0.38	GO:0007274	neuromuscular synaptic transmission
0.38	GO:0007528	neuromuscular junction development
0.38	GO:0097479	synaptic vesicle localization
0.37	GO:0006914	autophagy

0.80	GO:0019888	protein phosphatase regulator activity
0.44	GO:0004721	phosphoprotein phosphatase activity
0.37	GO:0008270	zinc ion binding
0.35	GO:0003676	nucleic acid binding
0.34	GO:0005515	protein binding

0.81	GO:0000159	protein phosphatase type 2A complex
0.37	GO:0005634	nucleus
0.33	GO:0005829	cytosol
0.33	GO:0043233	organelle lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.44

GO:0004721

tr|T1G9P4|T1G9P4_HELRO
Uncharacterized protein
Search

0.51	cAMP-dependent protein kinase catalytic subunit alpha

0.63	GO:0006468	protein phosphorylation
0.42	GO:0008359	regulation of bicoid mRNA localization
0.42	GO:0048682	sprouting of injured axon
0.41	GO:0007615	anesthesia-resistant memory
0.41	GO:0007228	positive regulation of hh target transcription factor activity
0.41	GO:0007448	anterior/posterior pattern specification, imaginal disc
0.41	GO:0008103	oocyte microtubule cytoskeleton polarization
0.41	GO:0007317	regulation of pole plasm oskar mRNA localization
0.41	GO:0040040	thermosensory behavior
0.41	GO:0008355	olfactory learning

0.69	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0060089	molecular transducer activity
0.33	GO:0005515	protein binding

0.39	GO:0030425	dendrite
0.39	GO:0044297	cell body
0.36	GO:0005952	cAMP-dependent protein kinase complex
0.35	GO:0005886	plasma membrane
0.34	GO:0045171	intercellular bridge
0.34	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0004674

tr|T1G9P5|T1G9P5_HELRO
Uncharacterized protein
Search

LOC108938752

0.69	Receptor-type tyrosine-protein phosphatase F (Fragment)

0.75	GO:0035335	peptidyl-tyrosine dephosphorylation
0.46	GO:1900121	negative regulation of receptor binding
0.46	GO:0031175	neuron projection development
0.46	GO:0048679	regulation of axon regeneration
0.45	GO:0031099	regeneration
0.43	GO:0006928	movement of cell or subcellular component
0.43	GO:0040011	locomotion
0.41	GO:0051674	localization of cell
0.40	GO:0048667	cell morphogenesis involved in neuron differentiation
0.40	GO:0120039	plasma membrane bounded cell projection morphogenesis

0.75	GO:0004725	protein tyrosine phosphatase activity
0.48	GO:0035373	chondroitin sulfate proteoglycan binding
0.42	GO:0032403	protein complex binding
0.38	GO:0008201	heparin binding
0.35	GO:0019198	transmembrane receptor protein phosphatase activity

0.44	GO:0043025	neuronal cell body
0.43	GO:0043005	neuron projection
0.35	GO:0070062	extracellular exosome
0.33	GO:0005887	integral component of plasma membrane

0.75

EC:3.1.3.48

GO:0004725

tr|T1G9P6|T1G9P6_HELRO
Uncharacterized protein
Search

0.65	Serine/threonine-protein kinase Doa

0.63	GO:0006468	protein phosphorylation
0.48	GO:0006486	protein glycosylation
0.36	GO:0006836	neurotransmitter transport
0.34	GO:0010212	response to ionizing radiation
0.34	GO:0043484	regulation of RNA splicing
0.33	GO:0016480	negative regulation of transcription by RNA polymerase III
0.33	GO:0018209	peptidyl-serine modification
0.33	GO:0018212	peptidyl-tyrosine modification

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0016757	transferase activity, transferring glycosyl groups
0.37	GO:0019905	syntaxin binding
0.35	GO:0003676	nucleic acid binding
0.33	GO:0042802	identical protein binding
0.33	GO:0004386	helicase activity

0.34	GO:0016604	nuclear body
0.31	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.44

EC:2.4

GO:0016757

tr|T1G9P7|T1G9P7_HELRO
Uncharacterized protein
Search

ERCC4

0.87	Excision repair cross-complementing rodent repair deficiency, complementation group 4

0.63	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.60	GO:0006281	DNA repair
0.55	GO:1905768	negative regulation of double-stranded telomeric DNA binding
0.54	GO:0061819	telomeric DNA-containing double minutes formation
0.54	GO:1905764	regulation of protection from non-homologous end joining at telomere
0.54	GO:1904506	negative regulation of telomere maintenance in response to DNA damage
0.53	GO:1904354	negative regulation of telomere capping
0.52	GO:1904357	negative regulation of telomere maintenance via telomere lengthening
0.52	GO:0009650	UV protection
0.51	GO:0000712	resolution of meiotic recombination intermediates

0.68	GO:0003697	single-stranded DNA binding
0.67	GO:0004520	endodeoxyribonuclease activity
0.52	GO:0001094	TFIID-class transcription factor binding
0.52	GO:0047485	protein N-terminus binding
0.51	GO:0008022	protein C-terminus binding
0.49	GO:0003684	damaged DNA binding
0.47	GO:0042802	identical protein binding
0.38	GO:0046982	protein heterodimerization activity
0.35	GO:0010521	telomerase inhibitor activity

0.57	GO:0000110	nucleotide-excision repair factor 1 complex
0.53	GO:0070522	ERCC4-ERCC1 complex
0.50	GO:0000784	nuclear chromosome, telomeric region
0.48	GO:0005669	transcription factor TFIID complex
0.30	GO:0016020	membrane

tr|T1G9P8|T1G9P8_HELRO
Uncharacterized protein
Search

0.77	Fibrillar collagen chain FAp1 alpha

0.43	GO:0009653	anatomical structure morphogenesis
0.42	GO:0007275	multicellular organism development
0.42	GO:0009888	tissue development
0.41	GO:0009612	response to mechanical stimulus
0.41	GO:0030199	collagen fibril organization
0.40	GO:0032964	collagen biosynthetic process
0.40	GO:0051239	regulation of multicellular organismal process
0.40	GO:0001957	intramembranous ossification
0.39	GO:0007605	sensory perception of sound
0.39	GO:0030154	cell differentiation

0.73	GO:0005201	extracellular matrix structural constituent
0.41	GO:0048407	platelet-derived growth factor binding
0.40	GO:0002020	protease binding
0.37	GO:0042802	identical protein binding
0.36	GO:0042302	structural constituent of cuticle
0.34	GO:0004867	serine-type endopeptidase inhibitor activity
0.34	GO:0046872	metal ion binding
0.33	GO:0046332	SMAD binding
0.33	GO:0005178	integrin binding
0.33	GO:0004871	signal transducer activity

0.61	GO:0005581	collagen trimer
0.43	GO:0005578	proteinaceous extracellular matrix
0.42	GO:0044420	extracellular matrix component
0.39	GO:0005615	extracellular space
0.38	GO:0099081	supramolecular polymer
0.34	GO:1905360	GTPase complex
0.34	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.34	GO:0005737	cytoplasm
0.33	GO:0019867	outer membrane
0.33	GO:1903561	extracellular vesicle

tr|T1G9P9|T1G9P9_HELRO
Uncharacterized protein
Search

NOP2

0.82	Ribosomal RNA methyltransferase NOP2

0.68	GO:0006364	rRNA processing
0.63	GO:0032259	methylation
0.47	GO:1901796	regulation of signal transduction by p53 class mediator
0.47	GO:0042273	ribosomal large subunit biogenesis
0.45	GO:0008284	positive regulation of cell proliferation
0.44	GO:0042255	ribosome assembly
0.39	GO:0009451	RNA modification
0.35	GO:0044260	cellular macromolecule metabolic process
0.34	GO:1902626	assembly of large subunit precursor of preribosome
0.33	GO:0006357	regulation of transcription by RNA polymerase II

0.68	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity
0.59	GO:0003723	RNA binding
0.42	GO:0008169	C-methyltransferase activity
0.41	GO:0140102	catalytic activity, acting on a rRNA
0.40	GO:0008173	RNA methyltransferase activity
0.34	GO:0005198	structural molecule activity
0.34	GO:0004386	helicase activity
0.33	GO:0005515	protein binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0003677	DNA binding

0.45	GO:0005730	nucleolus
0.36	GO:0005882	intermediate filament
0.34	GO:0030687	preribosome, large subunit precursor
0.33	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.42

GO:0008169

tr|T1G9Q0|T1G9Q0_HELRO
Uncharacterized protein
Search

PSMD7

0.73	26S proteasome non-ATPase regulatory subunit

0.41	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.38	GO:0021551	central nervous system morphogenesis
0.37	GO:1904888	cranial skeletal system development
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.35	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation
0.35	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia

0.41	GO:0042803	protein homodimerization activity
0.33	GO:0003743	translation initiation factor activity
0.33	GO:0003777	microtubule motor activity
0.33	GO:0008017	microtubule binding
0.33	GO:0003779	actin binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0008144	drug binding

0.81	GO:0005838	proteasome regulatory particle
0.40	GO:0005654	nucleoplasm
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen
0.34	GO:0005829	cytosol
0.34	GO:0070062	extracellular exosome
0.34	GO:0030425	dendrite
0.34	GO:0016459	myosin complex
0.30	GO:0016020	membrane

tr|T1G9Q1|T1G9Q1_HELRO
Uncharacterized protein
Search

0.41	NADH dehydrogenase 1 alpha subcomplex subunit

0.43	GO:1901006	ubiquinone-6 biosynthetic process
0.38	GO:0006694	steroid biosynthetic process
0.37	GO:0055114	oxidation-reduction process
0.35	GO:0032981	mitochondrial respiratory chain complex I assembly
0.35	GO:0009749	response to glucose
0.35	GO:0007623	circadian rhythm
0.34	GO:0006119	oxidative phosphorylation
0.33	GO:0006397	mRNA processing

0.58	GO:0050662	coenzyme binding
0.40	GO:0003954	NADH dehydrogenase activity
0.39	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity
0.35	GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
0.34	GO:0032403	protein complex binding
0.32	GO:0003676	nucleic acid binding

0.43	GO:0005747	mitochondrial respiratory chain complex I
0.35	GO:0005759	mitochondrial matrix
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.40

EC:1.6.99.3

GO:0003954

tr|T1G9Q2|T1G9Q2_HELRO
Uncharacterized protein
Search

0.74	Clathrin coat assembly protein ap-1

0.69	GO:0006886	intracellular protein transport
0.69	GO:0016192	vesicle-mediated transport
0.49	GO:0035646	endosome to melanosome transport
0.49	GO:0032438	melanosome organization
0.42	GO:2001136	negative regulation of endocytic recycling
0.41	GO:0033363	secretory granule organization
0.40	GO:0045746	negative regulation of Notch signaling pathway
0.40	GO:0048749	compound eye development
0.37	GO:0048565	digestive tract development
0.36	GO:0007420	brain development

0.37	GO:0008565	protein transporter activity
0.34	GO:0005515	protein binding
0.33	GO:0003887	DNA-directed DNA polymerase activity
0.32	GO:0003676	nucleic acid binding

0.79	GO:0030131	clathrin adaptor complex
0.41	GO:0030665	clathrin-coated vesicle membrane
0.41	GO:0035976	transcription factor AP-1 complex
0.39	GO:0030140	trans-Golgi network transport vesicle
0.39	GO:0005794	Golgi apparatus
0.39	GO:0030658	transport vesicle membrane
0.39	GO:0030120	vesicle coat
0.39	GO:0030660	Golgi-associated vesicle membrane
0.35	GO:0070062	extracellular exosome
0.35	GO:0035579	specific granule membrane

0.33

EC:2.7.7.7

GO:0003887

tr|T1G9Q3|T1G9Q3_HELRO
Uncharacterized protein
Search

tr|T1G9Q4|T1G9Q4_HELRO
Uncharacterized protein
Search

0.77	Gamma-secretase subunit Aph-1

0.75	GO:0016485	protein processing
0.73	GO:0043085	positive regulation of catalytic activity
0.46	GO:0007220	Notch receptor processing
0.44	GO:0007219	Notch signaling pathway

0.39

GO:0004175

endopeptidase activity

0.46	GO:0070765	gamma-secretase complex
0.41	GO:0005783	endoplasmic reticulum
0.40	GO:0005887	integral component of plasma membrane

tr|T1G9Q5|T1G9Q5_HELRO
Guanylate cyclase
Search

0.43	Guanylate cyclase

0.81	GO:0006182	cGMP biosynthetic process
0.63	GO:0035556	intracellular signal transduction
0.61	GO:0006468	protein phosphorylation
0.44	GO:0060038	cardiac muscle cell proliferation
0.40	GO:0007168	receptor guanylyl cyclase signaling pathway
0.35	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus
0.34	GO:0042127	regulation of cell proliferation
0.34	GO:0035725	sodium ion transmembrane transport
0.34	GO:0018212	peptidyl-tyrosine modification
0.34	GO:0007186	G-protein coupled receptor signaling pathway

0.81	GO:0004383	guanylate cyclase activity
0.61	GO:0004672	protein kinase activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0004016	adenylate cyclase activity
0.40	GO:0016941	natriuretic peptide receptor activity
0.35	GO:0017046	peptide hormone binding
0.34	GO:0005272	sodium channel activity
0.34	GO:0004930	G-protein coupled receptor activity

0.45	GO:0005622	intracellular
0.38	GO:0043234	protein complex
0.37	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.81

EC:4.6.1.2

GO:0004383

tr|T1G9Q6|T1G9Q6_HELRO
Uncharacterized protein
Search

FASN

0.71	Fatty acid synthase

0.53	GO:0071353	cellular response to interleukin-4
0.52	GO:0055114	oxidation-reduction process
0.49	GO:0030879	mammary gland development
0.48	GO:0009058	biosynthetic process
0.46	GO:0006631	fatty acid metabolic process
0.38	GO:0032100	positive regulation of appetite
0.36	GO:0006089	lactate metabolic process
0.36	GO:0001649	osteoblast differentiation
0.36	GO:0006084	acetyl-CoA metabolic process
0.35	GO:0045540	regulation of cholesterol biosynthetic process

0.84	GO:0004317	3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity
0.84	GO:0004313	[acyl-carrier-protein] S-acetyltransferase activity
0.83	GO:0016295	myristoyl-[acyl-carrier-protein] hydrolase activity
0.83	GO:0016296	palmitoyl-[acyl-carrier-protein] hydrolase activity
0.83	GO:0004320	oleoyl-[acyl-carrier-protein] hydrolase activity
0.82	GO:0004319	enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity
0.76	GO:0004314	[acyl-carrier-protein] S-malonyltransferase activity
0.74	GO:0004316	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
0.74	GO:0004315	3-oxoacyl-[acyl-carrier-protein] synthase activity
0.73	GO:0031177	phosphopantetheine binding

0.55	GO:0042587	glycogen granule
0.47	GO:0005794	Golgi apparatus
0.45	GO:0005829	cytosol
0.42	GO:0005739	mitochondrion
0.40	GO:0005886	plasma membrane
0.38	GO:0042470	melanosome
0.36	GO:0070062	extracellular exosome

0.84	EC:4.2.1.61	GO:0004317
0.84	KEGG:R04462	GO:0004317

tr|T1G9Q7|T1G9Q7_HELRO
Uncharacterized protein
Search

0.12	Protein N-terminal asparagine amidohydrolase

0.66	GO:0007613	memory
0.65	GO:0008344	adult locomotory behavior
0.59	GO:0006511	ubiquitin-dependent protein catabolic process

0.86

GO:0008418

protein-N-terminal asparagine amidohydrolase activity

0.50	GO:0005634	nucleus
0.43	GO:0005737	cytoplasm

0.86

EC:3.5.1

GO:0008418

tr|T1G9Q8|T1G9Q8_HELRO
Uncharacterized protein
Search

HELLS

0.58	Lymphoid-specific helicase

0.46	GO:0031508	pericentric heterochromatin assembly
0.45	GO:0006346	methylation-dependent chromatin silencing
0.45	GO:0010216	maintenance of DNA methylation
0.44	GO:0046651	lymphocyte proliferation
0.44	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway
0.44	GO:1990823	response to leukemia inhibitory factor
0.43	GO:0001655	urogenital system development
0.42	GO:0071345	cellular response to cytokine stimulus
0.41	GO:0006306	DNA methylation
0.40	GO:0044030	regulation of DNA methylation

0.60	GO:0004386	helicase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0003682	chromatin binding
0.33	GO:0016887	ATPase activity
0.33	GO:0003677	DNA binding
0.32	GO:0016740	transferase activity

0.44	GO:0005721	pericentric heterochromatin
0.38	GO:0005634	nucleus
0.34	GO:0031974	membrane-enclosed lumen
0.34	GO:1904949	ATPase complex
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0016887

tr|T1G9Q9|T1G9Q9_HELRO
Uncharacterized protein
Search

CSE1L

0.89	Putative nuclear export receptor cse1/cas importin beta superfamily

0.69	GO:0006886	intracellular protein transport
0.49	GO:0006611	protein export from nucleus
0.47	GO:0006606	protein import into nucleus
0.45	GO:0007589	body fluid secretion
0.36	GO:0032012	regulation of ARF protein signal transduction
0.34	GO:0065009	regulation of molecular function
0.34	GO:0008283	cell proliferation
0.34	GO:0006915	apoptotic process

0.79	GO:0008536	Ran GTPase binding
0.50	GO:0005049	nuclear export signal receptor activity
0.36	GO:0005086	ARF guanyl-nucleotide exchange factor activity

0.59	GO:0005634	nucleus
0.48	GO:0005829	cytosol
0.45	GO:0031974	membrane-enclosed lumen
0.43	GO:0044446	intracellular organelle part
0.43	GO:0012505	endomembrane system
0.40	GO:0031975	envelope
0.36	GO:0070062	extracellular exosome
0.35	GO:0009925	basal plasma membrane
0.35	GO:0016328	lateral plasma membrane
0.34	GO:0016324	apical plasma membrane

tr|T1G9R0|T1G9R0_HELRO
Uncharacterized protein
Search

0.11	Transducin-like enhancer protein 3

0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:0010468	regulation of gene expression
0.34	GO:0016055	Wnt signaling pathway
0.33	GO:0097659	nucleic acid-templated transcription
0.32	GO:0010467	gene expression
0.32	GO:0034645	cellular macromolecule biosynthetic process

0.33

GO:0005515

protein binding

0.58	GO:0005634	nucleus
0.45	GO:0005667	transcription factor complex
0.43	GO:0043233	organelle lumen
0.40	GO:0044446	intracellular organelle part

tr|T1G9R1|T1G9R1_HELRO
Uncharacterized protein
Search

tr|T1G9R2|T1G9R2_HELRO
DNA topoisomerase
Search

TOP3B

0.55	DNA topoisomerase

0.72	GO:0006265	DNA topological change
0.47	GO:0007059	chromosome segregation
0.33	GO:0006470	protein dephosphorylation

0.76	GO:0003917	DNA topoisomerase type I activity
0.55	GO:0003677	DNA binding
0.33	GO:0004721	phosphoprotein phosphatase activity
0.33	GO:0003723	RNA binding
0.33	GO:0005515	protein binding
0.32	GO:0046872	metal ion binding

0.49	GO:0000793	condensed chromosome
0.40	GO:0005634	nucleus

0.76

EC:5.99.1.2

GO:0003917

tr|T1G9R3|T1G9R3_HELRO
Uncharacterized protein
Search

TMEM144

0.45	Transmembrane protein 144

0.72

GO:0034219

carbohydrate transmembrane transport

0.71

GO:0015144

carbohydrate transmembrane transporter activity

0.30

GO:0044425

membrane part

tr|T1G9R4|T1G9R4_HELRO
Uncharacterized protein
Search

SF3B4

0.78	Spliceosomal protein on the X

0.48	GO:0048026	positive regulation of mRNA splicing, via spliceosome
0.36	GO:0008380	RNA splicing
0.36	GO:0006397	mRNA processing
0.34	GO:0006413	translational initiation
0.32	GO:0055114	oxidation-reduction process

0.59	GO:0003723	RNA binding
0.36	GO:0005199	structural constituent of cell wall
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.33	GO:0005515	protein binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0016491	oxidoreductase activity
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.49	GO:0005689	U12-type spliceosomal complex
0.33	GO:0005654	nucleoplasm

0.32

GO:0016491

tr|T1G9R5|T1G9R5_HELRO
Uncharacterized protein
Search

tr|T1G9R6|T1G9R6_HELRO
Uncharacterized protein
Search

HADHB

0.54	Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta

0.44	GO:0006635	fatty acid beta-oxidation
0.44	GO:0008340	determination of adult lifespan
0.34	GO:0033617	mitochondrial respiratory chain complex IV assembly
0.33	GO:0006508	proteolysis

0.64	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
0.41	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity
0.35	GO:0008234	cysteine-type peptidase activity
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0019001	guanyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.38	GO:0005739	mitochondrion
0.36	GO:0031968	organelle outer membrane
0.36	GO:0031974	membrane-enclosed lumen
0.36	GO:0009295	nucleoid
0.36	GO:0036125	fatty acid beta-oxidation multienzyme complex
0.36	GO:0005783	endoplasmic reticulum
0.35	GO:0019866	organelle inner membrane
0.34	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

0.64

EC:2.3.1

GO:0016747

tr|T1G9R7|T1G9R7_HELRO
Uncharacterized protein
Search

0.56	GO:0034462	small-subunit processome assembly
0.53	GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.53	GO:0000472	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.53	GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.36	GO:0048546	digestive tract morphogenesis
0.33	GO:0006508	proteolysis
0.32	GO:0055114	oxidation-reduction process

0.59	GO:0003723	RNA binding
0.35	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
0.34	GO:0004252	serine-type endopeptidase activity

0.52	GO:0030686	90S preribosome
0.49	GO:0005730	nucleolus
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:1.14.17

GO:0016715

tr|T1G9R8|T1G9R8_HELRO
Uncharacterized protein
Search

TBL2

0.96	Transducin beta like 2

0.67	GO:0042149	cellular response to glucose starvation
0.66	GO:0071456	cellular response to hypoxia
0.66	GO:0030968	endoplasmic reticulum unfolded protein response
0.35	GO:0006370	7-methylguanosine mRNA capping
0.35	GO:0035335	peptidyl-tyrosine dephosphorylation

0.66	GO:0051219	phosphoprotein binding
0.65	GO:0031369	translation initiation factor binding
0.62	GO:0019901	protein kinase binding
0.41	GO:0046983	protein dimerization activity
0.36	GO:0004484	mRNA guanylyltransferase activity
0.36	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.36	GO:0003723	RNA binding
0.35	GO:0004725	protein tyrosine phosphatase activity

0.57	GO:0005783	endoplasmic reticulum
0.36	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.36

EC:2.7.7.50

GO:0004484

tr|T1G9R9|T1G9R9_HELRO
Uncharacterized protein
Search

SLC34A2

0.91	Sodium phosphate cotransporter

0.81	GO:0044341	sodium-dependent phosphate transport
0.51	GO:0072506	trivalent inorganic anion homeostasis
0.51	GO:0072505	divalent inorganic anion homeostasis
0.51	GO:0055083	monovalent inorganic anion homeostasis
0.50	GO:0035725	sodium ion transmembrane transport
0.50	GO:0035435	phosphate ion transmembrane transport
0.50	GO:0030002	cellular anion homeostasis
0.50	GO:0043627	response to estrogen
0.46	GO:0001701	in utero embryonic development
0.42	GO:0010288	response to lead ion

0.81	GO:0015321	sodium-dependent phosphate transmembrane transporter activity
0.56	GO:0005436	sodium:phosphate symporter activity
0.48	GO:0031402	sodium ion binding
0.48	GO:0042301	phosphate ion binding
0.34	GO:0005096	GTPase activator activity
0.34	GO:0019904	protein domain specific binding
0.33	GO:0003924	GTPase activity
0.33	GO:0005525	GTP binding

0.53	GO:0016324	apical plasma membrane
0.52	GO:0005903	brush border
0.41	GO:0031982	vesicle
0.40	GO:0072686	mitotic spindle
0.39	GO:0016607	nuclear speck
0.36	GO:0031253	cell projection membrane
0.35	GO:0005737	cytoplasm
0.35	GO:0005902	microvillus
0.30	GO:0016021	integral component of membrane

tr|T1G9S0|T1G9S0_HELRO
Uncharacterized protein
Search

0.83	Acidic leucine-rich nuclear phosphoprotein 32 family member A

0.65	GO:0043486	histone exchange
0.65	GO:0006334	nucleosome assembly
0.62	GO:0042981	regulation of apoptotic process
0.59	GO:0006913	nucleocytoplasmic transport
0.49	GO:2000116	regulation of cysteine-type endopeptidase activity
0.47	GO:0046827	positive regulation of protein export from nucleus
0.46	GO:0010950	positive regulation of endopeptidase activity
0.44	GO:0045596	negative regulation of cell differentiation
0.44	GO:0043068	positive regulation of programmed cell death
0.42	GO:0021591	ventricular system development

0.65	GO:0042393	histone binding
0.44	GO:0070063	RNA polymerase binding
0.40	GO:0008017	microtubule binding
0.37	GO:0046872	metal ion binding
0.35	GO:0061630	ubiquitin protein ligase activity
0.34	GO:0003676	nucleic acid binding

0.55	GO:0005634	nucleus
0.47	GO:0031974	membrane-enclosed lumen
0.45	GO:0048471	perinuclear region of cytoplasm
0.43	GO:0044446	intracellular organelle part
0.42	GO:0005783	endoplasmic reticulum
0.41	GO:0043232	intracellular non-membrane-bounded organelle
0.36	GO:0043234	protein complex
0.35	GO:0000151	ubiquitin ligase complex
0.30	GO:0031224	intrinsic component of membrane

tr|T1G9S1|T1G9S1_HELRO
tRNA pseudouridine synthase
Search

0.34	tRNA pseudouridine synthase

0.72	GO:0001522	pseudouridine synthesis
0.63	GO:0008033	tRNA processing
0.44	GO:0016556	mRNA modification
0.34	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
0.33	GO:0023014	signal transduction by protein phosphorylation
0.32	GO:0006508	proteolysis

0.72	GO:0009982	pseudouridine synthase activity
0.59	GO:0003723	RNA binding
0.35	GO:0004675	transmembrane receptor protein serine/threonine kinase activity
0.34	GO:0004702	signal transducer, downstream of receptor, with serine/threonine kinase activity
0.33	GO:0004252	serine-type endopeptidase activity
0.33	GO:0016829	lyase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0046872	metal ion binding

0.39	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.72

EC:5.4.99.12

GO:0009982

tr|T1G9S2|T1G9S2_HELRO
Uncharacterized protein
Search

SAMHD1

0.95	SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1

0.73	GO:0046061	dATP catabolic process
0.72	GO:0006203	dGTP catabolic process
0.66	GO:0051289	protein homotetramerization
0.64	GO:0051607	defense response to virus
0.60	GO:0045088	regulation of innate immune response
0.56	GO:0090501	RNA phosphodiester bond hydrolysis
0.41	GO:0045087	innate immune response
0.38	GO:0044830	modulation by host of viral RNA genome replication
0.37	GO:1903901	negative regulation of viral life cycle
0.35	GO:0045893	positive regulation of transcription, DNA-templated

0.75	GO:0032560	guanyl deoxyribonucleotide binding
0.71	GO:0008832	dGTPase activity
0.58	GO:0042802	identical protein binding
0.56	GO:0004540	ribonuclease activity
0.53	GO:0008270	zinc ion binding
0.50	GO:0003723	RNA binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.56	GO:0005654	nucleoplasm
0.47	GO:0005886	plasma membrane
0.35	GO:0005667	transcription factor complex
0.30	GO:0016021	integral component of membrane

0.71	EC:3.1.5.1	GO:0008832
0.71	KEGG:R01856	GO:0008832

tr|T1G9S3|T1G9S3_HELRO
Uncharacterized protein
Search

0.53	GO:0055114	oxidation-reduction process
0.38	GO:0017085	response to insecticide
0.38	GO:0031000	response to caffeine
0.37	GO:0048252	lauric acid metabolic process
0.35	GO:0006805	xenobiotic metabolic process
0.35	GO:0007608	sensory perception of smell
0.35	GO:0019748	secondary metabolic process
0.33	GO:0019373	epoxygenase P450 pathway
0.33	GO:0016098	monoterpenoid metabolic process
0.33	GO:0021661	rhombomere 4 morphogenesis

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.66	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.35	GO:0010181	FMN binding
0.33	GO:0003958	NADPH-hemoprotein reductase activity
0.33	GO:0008746	NAD(P)+ transhydrogenase activity
0.32	GO:0019899	enzyme binding
0.32	GO:0009055	electron transfer activity
0.32	GO:0051537	2 iron, 2 sulfur cluster binding

0.37	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

0.68	EC:1.14	GO:0016705
0.33	KEGG:R00112	GO:0008746

tr|T1G9S4|T1G9S4_HELRO
Uncharacterized protein
Search

CYB561D2

0.93	Cytochrome b-561 domain containing 2

0.52

GO:0055114

oxidation-reduction process

0.35

GO:0046872

metal ion binding

0.30

GO:0044425

membrane part

tr|T1G9S5|T1G9S5_HELRO
Uncharacterized protein
Search

SF3B1

0.84	Splicing factor 3b subunit 1

0.69	GO:0000398	mRNA splicing, via spliceosome
0.64	GO:0060218	hematopoietic stem cell differentiation
0.64	GO:0060216	definitive hemopoiesis
0.64	GO:0030318	melanocyte differentiation
0.63	GO:0061515	myeloid cell development
0.62	GO:0014032	neural crest cell development
0.56	GO:0022618	ribonucleoprotein complex assembly
0.56	GO:0042981	regulation of apoptotic process
0.45	GO:0001825	blastocyst formation
0.43	GO:0009952	anterior/posterior pattern specification

0.57	GO:0003729	mRNA binding
0.42	GO:0003682	chromatin binding
0.39	GO:0005515	protein binding

0.80	GO:0034693	U11/U12 snRNP
0.78	GO:0005689	U12-type spliceosomal complex
0.75	GO:0005686	U2 snRNP
0.74	GO:0071013	catalytic step 2 spliceosome
0.69	GO:0016607	nuclear speck
0.62	GO:0071004	U2-type prespliceosome
0.44	GO:0016363	nuclear matrix
0.41	GO:0000785	chromatin

tr|T1G9S6|T1G9S6_HELRO
Histidine ammonia-lyase
Search

HAL

0.57	Histidine ammonia-lyase

0.77	GO:0019557	histidine catabolic process to glutamate and formate
0.77	GO:0043606	formamide metabolic process
0.44	GO:0060218	hematopoietic stem cell differentiation

0.81

GO:0004397

histidine ammonia-lyase activity

0.49

GO:0005737

cytoplasm

0.81

EC:4.3.1.3

GO:0004397

tr|T1G9S7|T1G9S7_HELRO
Uncharacterized protein
Search

DGCR8

0.65	Partner of drosha

0.54	GO:0031053	primary miRNA processing
0.51	GO:0072091	regulation of stem cell proliferation
0.46	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.37	GO:0007446	imaginal disc growth
0.37	GO:0030727	germarium-derived female germ-line cyst formation
0.37	GO:0007294	germarium-derived oocyte fate determination
0.36	GO:0016319	mushroom body development
0.35	GO:0010586	miRNA metabolic process

0.59	GO:0003723	RNA binding
0.49	GO:0032296	double-stranded RNA-specific ribonuclease activity
0.48	GO:0042803	protein homodimerization activity
0.47	GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters
0.43	GO:0020037	heme binding
0.33	GO:0046872	metal ion binding

0.56	GO:0070877	microprocessor complex
0.50	GO:0014069	postsynaptic density
0.38	GO:0005737	cytoplasm
0.36	GO:0005730	nucleolus
0.33	GO:0005654	nucleoplasm

0.47

EC:3.1.26

GO:0016891

tr|T1G9S8|T1G9S8_HELRO
Uncharacterized protein
Search

ABCG4

0.80	ATP-binding cassette subfamily G member 1 transcription variant 1

0.55	GO:0030301	cholesterol transport
0.52	GO:0032366	intracellular sterol transport
0.51	GO:1990830	cellular response to leukemia inhibitory factor
0.45	GO:0010874	regulation of cholesterol efflux
0.45	GO:0071403	cellular response to high density lipoprotein particle stimulus
0.45	GO:0045542	positive regulation of cholesterol biosynthetic process
0.44	GO:0034436	glycoprotein transport
0.44	GO:0032376	positive regulation of cholesterol transport
0.43	GO:0034374	low-density lipoprotein particle remodeling
0.43	GO:0010872	regulation of cholesterol esterification

0.61	GO:0016887	ATPase activity
0.56	GO:0017127	cholesterol transporter activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0042803	protein homodimerization activity
0.49	GO:0046982	protein heterodimerization activity
0.48	GO:1901618	organic hydroxy compound transmembrane transporter activity
0.44	GO:0034437	glycoprotein transporter activity
0.43	GO:0015399	primary active transmembrane transporter activity

0.42	GO:0055037	recycling endosome
0.41	GO:0009897	external side of plasma membrane
0.37	GO:0005739	mitochondrion
0.34	GO:0005794	Golgi apparatus
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.61

GO:0016887

tr|T1G9S9|T1G9S9_HELRO
Uncharacterized protein
Search

0.81	Ubiquitin conjugation factor E4 B

0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.73	GO:0016567	protein ubiquitination
0.53	GO:0008626	granzyme-mediated apoptotic signaling pathway
0.52	GO:0003222	ventricular trabecula myocardium morphogenesis
0.50	GO:0034976	response to endoplasmic reticulum stress
0.49	GO:0009411	response to UV
0.49	GO:0010498	proteasomal protein catabolic process
0.48	GO:0031175	neuron projection development
0.45	GO:0010243	response to organonitrogen compound
0.33	GO:0006313	transposition, DNA-mediated

0.85	GO:0034450	ubiquitin-ubiquitin ligase activity
0.45	GO:0019899	enzyme binding
0.39	GO:0032559	adenyl ribonucleotide binding
0.39	GO:0008144	drug binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0051082	unfolded protein binding
0.33	GO:0004803	transposase activity

0.76	GO:0000151	ubiquitin ligase complex
0.43	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|T1G9T0|T1G9T0_HELRO
Lipase maturation factor
Search

0.78	Lipase maturation factor

0.44

GO:0051604

protein maturation

0.33

GO:0005515

protein binding

0.71	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1G9T1|T1G9T1_HELRO
Uncharacterized protein
Search

0.50	GO:1903506	regulation of nucleic acid-templated transcription
0.50	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.50	GO:0010468	regulation of gene expression
0.35	GO:0006351	transcription, DNA-templated
0.32	GO:0007165	signal transduction

0.51	GO:0003676	nucleic acid binding
0.48	GO:0046872	metal ion binding
0.41	GO:0003700	DNA binding transcription factor activity
0.34	GO:0008201	heparin binding
0.33	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity

0.41	GO:0005622	intracellular
0.39	GO:0031974	membrane-enclosed lumen
0.38	GO:0043227	membrane-bounded organelle
0.37	GO:0043228	non-membrane-bounded organelle
0.36	GO:0044422	organelle part

0.33

EC:3.1.4.17

GO:0004114

tr|T1G9T2|T1G9T2_HELRO
Uncharacterized protein
Search

0.60	Vacuolar protein sorting-associated protein 26

0.61	GO:0007165	signal transduction
0.49	GO:0042147	retrograde transport, endosome to Golgi
0.46	GO:1990126	retrograde transport, endosome to plasma membrane
0.41	GO:0015031	protein transport
0.41	GO:0034613	cellular protein localization
0.39	GO:0071346	cellular response to interferon-gamma
0.32	GO:0055114	oxidation-reduction process

0.41	GO:0008565	protein transporter activity
0.35	GO:0004386	helicase activity
0.34	GO:0043168	anion binding
0.34	GO:1901265	nucleoside phosphate binding
0.33	GO:0008144	drug binding
0.33	GO:0097367	carbohydrate derivative binding
0.33	GO:0036094	small molecule binding
0.33	GO:0051537	2 iron, 2 sulfur cluster binding
0.33	GO:0003676	nucleic acid binding
0.33	GO:0005515	protein binding

0.49	GO:0030904	retromer complex
0.47	GO:0005768	endosome
0.44	GO:0005829	cytosol
0.43	GO:0005764	lysosome
0.43	GO:0044433	cytoplasmic vesicle part
0.42	GO:0098805	whole membrane
0.42	GO:0098588	bounding membrane of organelle
0.39	GO:0045335	phagocytic vesicle
0.34	GO:0070062	extracellular exosome

0.32

GO:0016491

tr|T1G9T3|T1G9T3_HELRO
Uncharacterized protein
Search

tr|T1G9T4|T1G9T4_HELRO
Uncharacterized protein
Search

NUDT3

0.50	Diadenosine and diphosphoinositol polyphosphate phosphohydrolase

0.58	GO:0071543	diphosphoinositol polyphosphate metabolic process
0.53	GO:1901909	diadenosine hexaphosphate catabolic process
0.53	GO:1901907	diadenosine pentaphosphate catabolic process
0.53	GO:1901910	adenosine 5'-(hexahydrogen pentaphosphate) metabolic process
0.52	GO:0009169	purine ribonucleoside monophosphate catabolic process
0.50	GO:0009154	purine ribonucleotide catabolic process
0.47	GO:0071545	inositol phosphate catabolic process
0.44	GO:0046626	regulation of insulin receptor signaling pathway
0.43	GO:0055088	lipid homeostasis
0.43	GO:0042593	glucose homeostasis

0.62	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity
0.53	GO:0034431	bis(5'-adenosyl)-hexaphosphatase activity
0.53	GO:0034432	bis(5'-adenosyl)-pentaphosphatase activity
0.52	GO:0050072	m7G(5')pppN diphosphatase activity
0.52	GO:0000298	endopolyphosphatase activity
0.45	GO:0052848	inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity
0.45	GO:0052844	inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity
0.45	GO:0052845	inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity
0.45	GO:0052846	inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity
0.45	GO:0052847	inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity

0.45	GO:0005829	cytosol
0.44	GO:0005634	nucleus
0.36	GO:0070062	extracellular exosome
0.34	GO:0005882	intermediate filament
0.33	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.62	EC:3.6.1.52	GO:0008486
0.62	KEGG:R05777	GO:0008486

tr|T1G9T5|T1G9T5_HELRO
Uncharacterized protein
Search

0.56	Enhancer of zeste 1 polycomb repressive complex 2 subunit

0.78	GO:0070734	histone H3-K27 methylation
0.33	GO:0006351	transcription, DNA-templated
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.71	GO:0018024	histone-lysine N-methyltransferase activity
0.38	GO:0003677	DNA binding

0.46

GO:0035098

ESC/E(Z) complex

0.71

EC:2.1.1.43

GO:0018024

tr|T1G9T6|T1G9T6_HELRO
Uncharacterized protein
Search

VCP

0.76	Transitional endoplasmic reticulum ATPase

0.58	GO:0061857	endoplasmic reticulum stress-induced pre-emptive quality control
0.57	GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway
0.57	GO:1903007	positive regulation of Lys63-specific deubiquitinase activity
0.57	GO:0042728	flavin-containing compound catabolic process
0.56	GO:0070842	aggresome assembly
0.56	GO:2000158	positive regulation of ubiquitin-specific protease activity
0.55	GO:0034214	protein hexamerization
0.55	GO:0010918	positive regulation of mitochondrial membrane potential
0.55	GO:0097352	autophagosome maturation
0.55	GO:1903862	positive regulation of oxidative phosphorylation

0.56	GO:0035800	deubiquitinase activator activity
0.55	GO:1904288	BAT3 complex binding
0.55	GO:0036435	K48-linked polyubiquitin modification-dependent protein binding
0.55	GO:0042288	MHC class I protein binding
0.55	GO:0030554	adenyl nucleotide binding
0.55	GO:1990381	ubiquitin-specific protease binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0019903	protein phosphatase binding

0.57	GO:1990730	VCP-NSFL1C complex
0.54	GO:0036513	Derlin-1 retrotranslocation complex
0.54	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex
0.53	GO:0035861	site of double-strand break
0.52	GO:0043209	myelin sheath
0.51	GO:0005811	lipid droplet
0.50	GO:0048471	perinuclear region of cytoplasm
0.47	GO:1905369	endopeptidase complex
0.47	GO:0005829	cytosol
0.47	GO:0005654	nucleoplasm

0.50

GO:0016787

tr|T1G9T7|T1G9T7_HELRO
Uncharacterized protein
Search

PPTC7

0.97	PTC7 protein phosphatase homolog a

0.38

GO:0006470

protein dephosphorylation

0.38	GO:0004721	phosphoprotein phosphatase activity
0.34	GO:0046872	metal ion binding

0.42	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.38

GO:0004721

tr|T1G9T8|T1G9T8_HELRO
Uncharacterized protein
Search

TMEM65

0.84	Transmembrane protein 65

0.51	GO:1903779	regulation of cardiac conduction
0.49	GO:0003231	cardiac ventricle development

0.33	GO:0035091	phosphatidylinositol binding
0.33	GO:0005515	protein binding

0.48	GO:0014704	intercalated disc
0.40	GO:0031966	mitochondrial membrane
0.40	GO:0019866	organelle inner membrane
0.39	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1G9T9|T1G9T9_HELRO
Uncharacterized protein
Search

MYO6

0.90	Unconventional myosin-VI

0.74	GO:0007018	microtubule-based movement
0.50	GO:0030330	DNA damage response, signal transduction by p53 class mediator
0.47	GO:0051046	regulation of secretion
0.45	GO:0045944	positive regulation of transcription by RNA polymerase II
0.44	GO:0006897	endocytosis
0.41	GO:0050954	sensory perception of mechanical stimulus
0.41	GO:0042491	inner ear auditory receptor cell differentiation
0.40	GO:0050982	detection of mechanical stimulus
0.38	GO:0050906	detection of stimulus involved in sensory perception
0.38	GO:0035479	angioblast cell migration from lateral mesoderm to midline

0.77	GO:0051015	actin filament binding
0.74	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0045296	cadherin binding
0.36	GO:0000146	microfilament motor activity
0.36	GO:0042802	identical protein binding
0.35	GO:0005516	calmodulin binding

0.77	GO:0016459	myosin complex
0.49	GO:0031941	filamentous actin
0.49	GO:0045334	clathrin-coated endocytic vesicle
0.48	GO:0001726	ruffle
0.47	GO:0031965	nuclear membrane
0.47	GO:0048471	perinuclear region of cytoplasm
0.46	GO:0016591	DNA-directed RNA polymerase II, holoenzyme
0.44	GO:0005794	Golgi apparatus
0.39	GO:0005902	microvillus
0.38	GO:0031256	leading edge membrane

tr|T1G9U0|T1G9U0_HELRO
Uncharacterized protein
Search

0.58	GO:0007257	activation of JUN kinase activity
0.53	GO:0007585	respiratory gaseous exchange
0.53	GO:0048286	lung alveolus development
0.53	GO:0060425	lung morphogenesis
0.51	GO:0016192	vesicle-mediated transport
0.51	GO:0030900	forebrain development
0.51	GO:0007411	axon guidance
0.50	GO:0001701	in utero embryonic development
0.50	GO:0009791	post-embryonic development
0.47	GO:0030421	defecation

0.60	GO:0008432	JUN kinase binding
0.59	GO:0005078	MAP-kinase scaffold activity
0.57	GO:0019894	kinesin binding
0.56	GO:0030159	receptor signaling complex scaffold activity
0.56	GO:0016301	kinase activity
0.55	GO:0031434	mitogen-activated protein kinase kinase binding
0.54	GO:0031435	mitogen-activated protein kinase kinase kinase binding
0.33	GO:0008476	protein-tyrosine sulfotransferase activity
0.32	GO:0005509	calcium ion binding

0.56	GO:0030424	axon
0.54	GO:0005790	smooth endoplasmic reticulum
0.53	GO:0032589	neuron projection membrane
0.52	GO:0036477	somatodendritic compartment
0.48	GO:0000139	Golgi membrane
0.44	GO:0044297	cell body
0.42	GO:0045202	synapse
0.40	GO:0120111	neuron projection cytoplasm
0.36	GO:0030426	growth cone
0.36	GO:0044306	neuron projection terminus

0.33

EC:2.8.2.20

GO:0008476

tr|T1G9U1|T1G9U1_HELRO
Adenylosuccinate lyase
Search

ADSL

0.48	Adenylosuccinate lyase

0.73	GO:0044208	'de novo' AMP biosynthetic process
0.68	GO:0006189	'de novo' IMP biosynthetic process
0.39	GO:0051262	protein tetramerization
0.34	GO:0035278	miRNA mediated inhibition of translation
0.34	GO:0006106	fumarate metabolic process
0.32	GO:0006508	proteolysis

0.77	GO:0004018	N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity
0.76	GO:0070626	(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity
0.33	GO:0070001	aspartic-type peptidase activity
0.33	GO:0004175	endopeptidase activity
0.32	GO:0003676	nucleic acid binding

0.37	GO:0005829	cytosol
0.35	GO:0005739	mitochondrion

0.77	EC:4.3.2.2	GO:0004018
0.77	KEGG:R01083	GO:0004018

tr|T1G9U2|T1G9U2_HELRO
Uncharacterized protein
Search

0.55	Histone-lysine n-methyltransferase trr (Fragment)

0.83	GO:0051568	histone H3-K4 methylation
0.40	GO:0007458	progression of morphogenetic furrow involved in compound eye morphogenesis
0.40	GO:1900114	positive regulation of histone H3-K9 trimethylation
0.40	GO:0035332	positive regulation of hippo signaling
0.39	GO:0035075	response to ecdysone
0.37	GO:0045893	positive regulation of transcription, DNA-templated
0.34	GO:0061029	eyelid development in camera-type eye
0.34	GO:0045652	regulation of megakaryocyte differentiation
0.34	GO:0048146	positive regulation of fibroblast proliferation
0.34	GO:0035264	multicellular organism growth

0.84	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.50	GO:0046872	metal ion binding
0.38	GO:0003713	transcription coactivator activity
0.37	GO:0005102	receptor binding
0.34	GO:0035299	inositol pentakisphosphate 2-kinase activity
0.34	GO:0003676	nucleic acid binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0032561	guanyl ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0016746	transferase activity, transferring acyl groups

0.83	GO:0044666	MLL3/4 complex
0.39	GO:0005703	polytene chromosome puff
0.34	GO:0005874	microtubule
0.30	GO:0031224	intrinsic component of membrane

0.34	EC:2.7.1.158	GO:0035299
0.34	KEGG:R05202	GO:0035299

tr|T1G9U3|T1G9U3_HELRO
Uncharacterized protein
Search

0.49	Mortality factor 4-like protein 1

0.73	GO:0016569	covalent chromatin modification
0.57	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.50	GO:0018393	internal peptidyl-lysine acetylation
0.50	GO:0043486	histone exchange
0.48	GO:0051304	chromosome separation
0.47	GO:1902679	negative regulation of RNA biosynthetic process
0.39	GO:0006476	protein deacetylation

0.50	GO:0035064	methylated histone binding
0.49	GO:0004402	histone acetyltransferase activity

0.79	GO:0016580	Sin3 complex
0.77	GO:0035267	NuA4 histone acetyltransferase complex

0.49

GO:0004402

tr|T1G9U4|T1G9U4_HELRO
Uncharacterized protein
Search

0.86	Putative metal ion transmembrane transporter

0.66	GO:0030001	metal ion transport
0.55	GO:0055085	transmembrane transport
0.45	GO:0006882	cellular zinc ion homeostasis
0.44	GO:0072511	divalent inorganic cation transport
0.43	GO:0007506	gonadal mesoderm development
0.43	GO:0035147	branch fusion, open tracheal system
0.43	GO:0035262	gonad morphogenesis
0.42	GO:0008354	germ cell migration
0.40	GO:0007417	central nervous system development
0.39	GO:0034224	cellular response to zinc ion starvation

0.68	GO:0046873	metal ion transmembrane transporter activity
0.46	GO:0072509	divalent inorganic cation transmembrane transporter activity
0.38	GO:0005509	calcium ion binding
0.34	GO:0005537	mannose binding
0.33	GO:0004190	aspartic-type endopeptidase activity
0.33	GO:0008536	Ran GTPase binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0003677	DNA binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0032555	purine ribonucleotide binding

0.42	GO:0016323	basolateral plasma membrane
0.40	GO:0005887	integral component of plasma membrane
0.40	GO:0009986	cell surface
0.34	GO:0031258	lamellipodium membrane
0.34	GO:0016324	apical plasma membrane
0.34	GO:0005768	endosome
0.32	GO:0005789	endoplasmic reticulum membrane
0.32	GO:0005794	Golgi apparatus

0.33

EC:3.4.23

GO:0004190

tr|T1G9U5|T1G9U5_HELRO
Uncharacterized protein
Search

tr|T1G9U6|T1G9U6_HELRO
Uncharacterized protein
Search

0.70	Poly(rC) binding protein 4

0.34	GO:0075522	IRES-dependent viral translational initiation
0.33	GO:0050687	negative regulation of defense response to virus
0.33	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.33	GO:0007186	G-protein coupled receptor signaling pathway
0.32	GO:0039694	viral RNA genome replication
0.32	GO:0001522	pseudouridine synthesis
0.32	GO:0006364	rRNA processing

0.59	GO:0003723	RNA binding
0.34	GO:1990829	C-rich single-stranded DNA binding
0.33	GO:0031625	ubiquitin protein ligase binding
0.33	GO:0004930	G-protein coupled receptor activity
0.32	GO:0016787	hydrolase activity

0.34	GO:0005829	cytosol
0.33	GO:0005634	nucleus
0.33	GO:0043233	organelle lumen
0.33	GO:0072588	box H/ACA RNP complex
0.32	GO:0044446	intracellular organelle part
0.32	GO:1902494	catalytic complex
0.32	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

0.32

GO:0016787

tr|T1G9U7|T1G9U7_HELRO
Uncharacterized protein
Search

0.60	GO:0006508	proteolysis
0.53	GO:0009405	pathogenesis
0.47	GO:0007229	integrin-mediated signaling pathway
0.40	GO:0006915	apoptotic process
0.38	GO:0007338	single fertilization
0.38	GO:0007155	cell adhesion
0.36	GO:0010604	positive regulation of macromolecule metabolic process
0.36	GO:0032501	multicellular organismal process
0.35	GO:0034241	positive regulation of macrophage fusion
0.35	GO:0042117	monocyte activation

0.69	GO:0004222	metalloendopeptidase activity
0.56	GO:0090729	toxin activity
0.51	GO:0046872	metal ion binding
0.35	GO:0043236	laminin binding
0.35	GO:0005178	integrin binding
0.35	GO:0016504	peptidase activator activity
0.35	GO:0005518	collagen binding
0.34	GO:0052689	carboxylic ester hydrolase activity
0.34	GO:0017124	SH3 domain binding
0.33	GO:0003682	chromatin binding

0.42	GO:0005576	extracellular region
0.38	GO:0005739	mitochondrion
0.37	GO:0005886	plasma membrane
0.34	GO:0009986	cell surface
0.34	GO:0008278	cohesin complex
0.30	GO:0016021	integral component of membrane

0.69	EC:3.4.24	GO:0004222
0.34	KEGG:R00630	GO:0052689

tr|T1G9U8|T1G9U8_HELRO
Uncharacterized protein
Search

0.61	GO:0006508	proteolysis
0.59	GO:0007229	integrin-mediated signaling pathway
0.47	GO:0009405	pathogenesis
0.35	GO:0060468	prevention of polyspermy
0.35	GO:0042035	regulation of cytokine biosynthetic process
0.34	GO:0006915	apoptotic process
0.34	GO:0042127	regulation of cell proliferation

0.70	GO:0004222	metalloendopeptidase activity
0.52	GO:0046872	metal ion binding
0.50	GO:0090729	toxin activity
0.40	GO:0002020	protease binding

0.37	GO:1990913	sperm head plasma membrane
0.37	GO:0005576	extracellular region
0.36	GO:0009897	external side of plasma membrane
0.30	GO:0016021	integral component of membrane

0.70

GO:0004222

tr|T1G9U9|T1G9U9_HELRO
Uncharacterized protein
Search

0.38	Sorting nexin

0.59	GO:0042147	retrograde transport, endosome to Golgi
0.53	GO:0006886	intracellular protein transport
0.36	GO:0006897	endocytosis

0.76

GO:0035091

phosphatidylinositol binding

0.60	GO:0030904	retromer complex
0.52	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|T1G9V0|T1G9V0_HELRO
Uncharacterized protein
Search

0.75	GO:0061723	glycophagy
0.74	GO:0035096	larval midgut cell programmed cell death
0.65	GO:0009267	cellular response to starvation
0.64	GO:0006497	protein lipidation
0.62	GO:0010506	regulation of autophagy
0.56	GO:0000045	autophagosome assembly
0.48	GO:0098792	xenophagy
0.48	GO:0039689	negative stranded viral RNA replication
0.45	GO:0018410	C-terminal protein amino acid modification
0.41	GO:0034613	cellular protein localization

0.54	GO:0019776	Atg8 ligase activity
0.43	GO:0051020	GTPase binding
0.43	GO:0042802	identical protein binding
0.41	GO:0043531	ADP binding
0.40	GO:0004672	protein kinase activity
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0043565	sequence-specific DNA binding
0.37	GO:0008144	drug binding
0.36	GO:0008270	zinc ion binding
0.36	GO:0008017	microtubule binding

0.58	GO:0000421	autophagosome membrane
0.54	GO:0034274	Atg12-Atg5-Atg16 complex
0.45	GO:0005930	axoneme
0.37	GO:0008352	katanin complex
0.35	GO:0005874	microtubule
0.35	GO:0031514	motile cilium
0.30	GO:0016021	integral component of membrane

tr|T1G9V1|T1G9V1_HELRO
Bardet-Biedl syndrome 2 protein homolog
Search

BBS2

0.96	Bardet-Biedl syndrome 2 protein homolog

0.81	GO:1905515	non-motile cilium assembly
0.58	GO:0038108	negative regulation of appetite by leptin-mediated signaling pathway
0.58	GO:0060295	regulation of cilium movement involved in cell motility
0.58	GO:0014824	artery smooth muscle contraction
0.57	GO:0003356	regulation of cilium beat frequency
0.57	GO:0007288	sperm axoneme assembly
0.57	GO:0021756	striatum development
0.57	GO:0040015	negative regulation of multicellular organism growth
0.56	GO:0042311	vasodilation
0.56	GO:1990778	protein localization to cell periphery

0.56	GO:0001103	RNA polymerase II repressing transcription factor binding
0.32	GO:0046872	metal ion binding

0.80	GO:0034464	BBSome
0.71	GO:0060170	ciliary membrane
0.64	GO:0005815	microtubule organizing center
0.55	GO:0032420	stereocilium
0.55	GO:0005902	microvillus
0.54	GO:0031514	motile cilium
0.45	GO:0005737	cytoplasm
0.33	GO:0005634	nucleus

tr|T1G9V2|T1G9V2_HELRO
Annexin
Search

0.63

Annexin

0.37	GO:0030011	maintenance of cell polarity
0.37	GO:0090066	regulation of anatomical structure size
0.36	GO:0006888	ER to Golgi vesicle-mediated transport
0.36	GO:0035295	tube development
0.36	GO:0048081	positive regulation of cuticle pigmentation
0.36	GO:0003331	positive regulation of extracellular matrix constituent secretion
0.35	GO:0048513	animal organ development
0.35	GO:0006886	intracellular protein transport
0.35	GO:0034394	protein localization to cell surface
0.35	GO:0071711	basement membrane organization

0.78	GO:0005544	calcium-dependent phospholipid binding
0.68	GO:0005509	calcium ion binding
0.35	GO:0030507	spectrin binding
0.34	GO:0008270	zinc ion binding
0.34	GO:0003779	actin binding
0.32	GO:0004930	G-protein coupled receptor activity

0.37	GO:0030127	COPII vesicle coat
0.36	GO:0005938	cell cortex
0.35	GO:0070971	endoplasmic reticulum exit site
0.34	GO:0015629	actin cytoskeleton
0.33	GO:0044430	cytoskeletal part
0.30	GO:0016021	integral component of membrane

tr|T1G9V3|T1G9V3_HELRO
Uncharacterized protein
Search

0.43	Melanotransferrin

0.54	GO:0010756	positive regulation of plasminogen activation
0.54	GO:0055072	iron ion homeostasis
0.54	GO:0090091	positive regulation of extracellular matrix disassembly
0.53	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading
0.53	GO:0097286	iron ion import
0.49	GO:0019991	septate junction assembly
0.38	GO:0042127	regulation of cell proliferation
0.37	GO:0001558	regulation of cell growth
0.37	GO:0043086	negative regulation of catalytic activity
0.36	GO:0006501	C-terminal protein lipidation

0.47	GO:0046872	metal ion binding
0.38	GO:0004610	phosphoacetylglucosamine mutase activity
0.37	GO:0004857	enzyme inhibitor activity
0.35	GO:0005515	protein binding
0.35	GO:0004601	peroxidase activity
0.34	GO:0043539	protein serine/threonine kinase activator activity
0.34	GO:0020037	heme binding
0.34	GO:0008201	heparin binding
0.34	GO:0001530	lipopolysaccharide binding
0.33	GO:0061135	endopeptidase regulator activity

0.70	GO:0005615	extracellular space
0.56	GO:0046658	anchored component of plasma membrane
0.49	GO:0005918	septate junction
0.48	GO:0009986	cell surface
0.47	GO:0055037	recycling endosome
0.46	GO:0005769	early endosome
0.38	GO:1903561	extracellular vesicle
0.36	GO:0005788	endoplasmic reticulum lumen
0.34	GO:0005829	cytosol
0.34	GO:0005887	integral component of plasma membrane

0.38	EC:5.4.2.3	GO:0004610
0.38	KEGG:R08193	GO:0004610

tr|T1G9V4|T1G9V4_HELRO
Uncharacterized protein
Search

0.27	3-oxoacyl-acyl-carrier-protein reductase

0.52

GO:0055114

oxidation-reduction process

0.53	GO:0016491	oxidoreductase activity
0.35	GO:0004312	fatty acid synthase activity
0.32	GO:0003677	DNA binding

0.30

GO:0031224

intrinsic component of membrane

0.53

GO:0016491

tr|T1G9V5|T1G9V5_HELRO
Uncharacterized protein
Search

0.69	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.43	GO:0042632	cholesterol homeostasis
0.43	GO:0070873	regulation of glycogen metabolic process
0.43	GO:0070328	triglyceride homeostasis
0.41	GO:0042594	response to starvation
0.41	GO:0030522	intracellular receptor signaling pathway

0.65	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.62	GO:0003707	steroid hormone receptor activity
0.61	GO:0003700	DNA binding transcription factor activity
0.41	GO:0001012	RNA polymerase II regulatory region DNA binding
0.40	GO:0003690	double-stranded DNA binding
0.33	GO:0005509	calcium ion binding

0.61	GO:0005634	nucleus
0.33	GO:0005911	cell-cell junction

tr|T1G9V6|T1G9V6_HELRO
Sideroflexin
Search

SFXN5

0.81	Sideroflexin

0.60	GO:0034220	ion transmembrane transport
0.37	GO:0015746	citrate transport
0.36	GO:0055072	iron ion homeostasis
0.35	GO:0015074	DNA integration
0.35	GO:0070164	negative regulation of adiponectin secretion
0.34	GO:2000008	regulation of protein localization to cell surface
0.34	GO:0071468	cellular response to acidic pH

0.60	GO:0015075	ion transmembrane transporter activity
0.37	GO:0017137	Rab GTPase binding
0.36	GO:0005342	organic acid transmembrane transporter activity
0.34	GO:0015318	inorganic molecular entity transmembrane transporter activity
0.34	GO:0043015	gamma-tubulin binding
0.33	GO:0003676	nucleic acid binding

0.57	GO:0031966	mitochondrial membrane
0.43	GO:0019866	organelle inner membrane
0.33	GO:0031968	organelle outer membrane
0.33	GO:0005815	microtubule organizing center
0.30	GO:0031224	intrinsic component of membrane

tr|T1G9V7|T1G9V7_HELRO
Transporter
Search

0.48	Transporter

0.76	GO:0006836	neurotransmitter transport
0.55	GO:0055085	transmembrane transport
0.45	GO:0071260	cellular response to mechanical stimulus
0.42	GO:0099509	regulation of presynaptic cytosolic calcium ion concentration
0.41	GO:0015872	dopamine transport
0.41	GO:1990834	response to odorant
0.41	GO:0042745	circadian sleep/wake cycle
0.40	GO:0030431	sleep
0.40	GO:0008344	adult locomotory behavior
0.39	GO:0015718	monocarboxylic acid transport

0.79	GO:0005328	neurotransmitter:sodium symporter activity
0.42	GO:0019811	cocaine binding
0.41	GO:0005329	dopamine transmembrane transporter activity
0.41	GO:0015185	gamma-aminobutyric acid transmembrane transporter activity
0.41	GO:0015355	secondary active monocarboxylate transmembrane transporter activity
0.40	GO:0005343	organic acid:sodium symporter activity
0.40	GO:0015296	anion:cation symporter activity
0.40	GO:0005416	amino acid:cation symporter activity
0.33	GO:0004721	phosphoprotein phosphatase activity
0.33	GO:0005368	taurine transmembrane transporter activity

0.46	GO:0097386	glial cell projection
0.41	GO:0097458	neuron part
0.40	GO:0005887	integral component of plasma membrane
0.39	GO:0044456	synapse part

0.33

GO:0004721

tr|T1G9V8|T1G9V8_HELRO
Uncharacterized protein
Search

ORC2

0.79	Origin recognition complex, subunit 2

0.66	GO:0006260	DNA replication
0.34	GO:0000082	G1/S transition of mitotic cell cycle
0.34	GO:0000122	negative regulation of transcription by RNA polymerase II
0.33	GO:0000413	protein peptidyl-prolyl isomerization
0.33	GO:0006457	protein folding

0.53	GO:0003688	DNA replication origin binding
0.34	GO:0003682	chromatin binding
0.33	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.33	GO:0005515	protein binding

0.82	GO:0000808	origin recognition complex
0.61	GO:0005634	nucleus
0.55	GO:0000939	condensed chromosome inner kinetochore
0.53	GO:0000792	heterochromatin
0.51	GO:0000781	chromosome, telomeric region
0.51	GO:0005813	centrosome
0.48	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

0.33