Queries 22001 to 23000

GO:0004252

tr|T1G619|T1G619_HELRO
Uncharacterized protein
Search

NCS-2

0.51	Calcium-binding protein M

0.39	GO:1905949	negative regulation of calcium ion import across plasma membrane
0.39	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.37	GO:0042327	positive regulation of phosphorylation
0.36	GO:0043085	positive regulation of catalytic activity
0.36	GO:0009966	regulation of signal transduction
0.33	GO:0007602	phototransduction
0.33	GO:0007601	visual perception
0.33	GO:0006270	DNA replication initiation
0.33	GO:0006508	proteolysis
0.33	GO:0005975	carbohydrate metabolic process

0.70	GO:0005509	calcium ion binding
0.39	GO:0098744	1-phosphatidylinositol 4-kinase activator activity
0.34	GO:0008061	chitin binding
0.33	GO:0004252	serine-type endopeptidase activity
0.32	GO:0016301	kinase activity

0.37	GO:0000139	Golgi membrane
0.34	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0004252

tr|T1G620|T1G620_HELRO
Uncharacterized protein
Search

0.58	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta

0.44	GO:0016256	N-glycan processing to lysosome
0.43	GO:0033299	secretion of lysosomal enzymes
0.41	GO:0007040	lysosome organization
0.39	GO:0046835	carbohydrate phosphorylation
0.38	GO:0006629	lipid metabolic process
0.36	GO:0055114	oxidation-reduction process

0.59	GO:0005509	calcium ion binding
0.57	GO:0016772	transferase activity, transferring phosphorus-containing groups
0.43	GO:0102965	alcohol-forming fatty acyl-CoA reductase activity
0.43	GO:0080019	fatty-acyl-CoA reductase (alcohol-forming) activity
0.32	GO:0016887	ATPase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.39	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

0.57

EC:2.7

GO:0016772

tr|T1G621|T1G621_HELRO
Uncharacterized protein
Search

0.41	Casein kinase I

0.63	GO:0006468	protein phosphorylation
0.42	GO:0010895	negative regulation of ergosterol biosynthetic process
0.41	GO:0018209	peptidyl-serine modification
0.41	GO:0030999	linear element assembly
0.41	GO:0010845	positive regulation of reciprocal meiotic recombination
0.41	GO:0010620	negative regulation of transcription by transcription factor catabolism
0.40	GO:2001159	regulation of protein localization by the Cvt pathway
0.40	GO:2000370	positive regulation of clathrin-dependent endocytosis
0.39	GO:0051455	attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation
0.39	GO:0016192	vesicle-mediated transport

0.64	GO:0004672	protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.37	GO:0042802	identical protein binding
0.33	GO:0005198	structural molecule activity
0.32	GO:0005057	signal transducer activity, downstream of receptor

0.40	GO:0033551	monopolin complex
0.39	GO:0005634	nucleus
0.39	GO:1990429	peroxisomal importomer complex
0.38	GO:0030688	preribosome, small subunit precursor
0.38	GO:0005816	spindle pole body
0.38	GO:0000407	phagophore assembly site
0.37	GO:0005794	Golgi apparatus
0.36	GO:0000329	fungal-type vacuole membrane
0.35	GO:0005886	plasma membrane
0.34	GO:0005923	bicellular tight junction

tr|T1G622|T1G622_HELRO
Uncharacterized protein
Search

COX10

0.41	Protoheme IX farnesyltransferase

0.80	GO:0048033	heme o metabolic process
0.72	GO:0006783	heme biosynthetic process
0.49	GO:0008535	respiratory chain complex IV assembly
0.48	GO:0046160	heme a metabolic process
0.48	GO:0000266	mitochondrial fission
0.42	GO:0045333	cellular respiration
0.42	GO:1902600	hydrogen ion transmembrane transport
0.41	GO:0022900	electron transport chain
0.34	GO:0018343	protein farnesylation
0.34	GO:0006368	transcription elongation from RNA polymerase II promoter

0.80	GO:0008495	protoheme IX farnesyltransferase activity
0.43	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.43	GO:0015002	heme-copper terminal oxidase activity
0.42	GO:0015078	hydrogen ion transmembrane transporter activity
0.41	GO:0009055	electron transfer activity

0.55	GO:0031966	mitochondrial membrane
0.46	GO:0005730	nucleolus
0.45	GO:0070069	cytochrome complex
0.44	GO:0005829	cytosol
0.34	GO:0016593	Cdc73/Paf1 complex
0.33	GO:0005886	plasma membrane
0.33	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.80

EC:2.5.1

GO:0008495

tr|T1G623|T1G623_HELRO
Uncharacterized protein
Search

0.70	GO:0006730	one-carbon metabolic process
0.39	GO:0002009	morphogenesis of an epithelium
0.37	GO:0046903	secretion

0.78	GO:0004089	carbonate dehydratase activity
0.63	GO:0008270	zinc ion binding

0.53	GO:0031225	anchored component of membrane
0.43	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.78

EC:4.2.1.1

GO:0004089

tr|T1G624|T1G624_HELRO
Uncharacterized protein
Search

0.43	GO:0032501	multicellular organismal process
0.43	GO:0051239	regulation of multicellular organismal process
0.42	GO:0006898	receptor-mediated endocytosis
0.41	GO:0048070	regulation of developmental pigmentation
0.41	GO:0050793	regulation of developmental process
0.41	GO:0032879	regulation of localization
0.41	GO:0048856	anatomical structure development
0.39	GO:0006508	proteolysis
0.38	GO:0015918	sterol transport
0.38	GO:0045927	positive regulation of growth

0.66	GO:0005509	calcium ion binding
0.41	GO:0004252	serine-type endopeptidase activity
0.39	GO:0005044	scavenger receptor activity
0.38	GO:0015248	sterol transporter activity
0.34	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.33	GO:0030247	polysaccharide binding
0.33	GO:0005515	protein binding
0.32	GO:0003777	microtubule motor activity
0.32	GO:0008168	methyltransferase activity
0.32	GO:0004930	G-protein coupled receptor activity

0.43	GO:0016324	apical plasma membrane
0.43	GO:0043235	receptor complex
0.39	GO:0030139	endocytic vesicle
0.37	GO:0005798	Golgi-associated vesicle
0.36	GO:0012505	endomembrane system
0.35	GO:0098589	membrane region
0.35	GO:0031526	brush border membrane
0.35	GO:0009986	cell surface
0.34	GO:0030425	dendrite
0.34	GO:0030424	axon

0.41

GO:0004252

tr|T1G625|T1G625_HELRO
Uncharacterized protein
Search

0.52	ATP synthase mitochondrial F1 complex assembly factor 2

0.84

GO:0043461

proton-transporting ATP synthase complex assembly

0.30

GO:0016021

integral component of membrane

tr|T1G626|T1G626_HELRO
Uncharacterized protein
Search

0.34	Protoheme IX farnesyltransferase

0.80	GO:0048033	heme o metabolic process
0.72	GO:0006783	heme biosynthetic process
0.46	GO:0046160	heme a metabolic process
0.40	GO:0008535	respiratory chain complex IV assembly
0.39	GO:0045333	cellular respiration
0.38	GO:0000266	mitochondrial fission
0.37	GO:1902600	hydrogen ion transmembrane transport
0.36	GO:0022900	electron transport chain
0.34	GO:0019510	S-adenosylhomocysteine catabolic process
0.33	GO:0006730	one-carbon metabolic process

0.80	GO:0008495	protoheme IX farnesyltransferase activity
0.37	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.37	GO:0015002	heme-copper terminal oxidase activity
0.37	GO:0015078	hydrogen ion transmembrane transporter activity
0.36	GO:0009055	electron transfer activity
0.34	GO:0004013	adenosylhomocysteinase activity
0.33	GO:0051287	NAD binding
0.33	GO:0043565	sequence-specific DNA binding
0.33	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.32	GO:0032559	adenyl ribonucleotide binding

0.56	GO:0031966	mitochondrial membrane
0.38	GO:0070069	cytochrome complex
0.38	GO:0005730	nucleolus
0.37	GO:0005829	cytosol
0.33	GO:0005694	chromosome
0.30	GO:0016021	integral component of membrane

0.80

EC:2.5.1

GO:0008495

tr|T1G627|T1G627_HELRO
Uncharacterized protein
Search

ENKUR

0.94	Enkurin, TRPC channel-interacting protein

0.37

GO:0009116

nucleoside metabolic process

0.78	GO:0005516	calmodulin binding
0.44	GO:0017124	SH3 domain binding

0.85	GO:0097228	sperm principal piece
0.84	GO:0001669	acrosomal vesicle

tr|T1G628|T1G628_HELRO
Uncharacterized protein
Search

0.68	ADP-ribosylation factor-binding protein GGA3

0.69	GO:0006886	intracellular protein transport
0.62	GO:0016192	vesicle-mediated transport
0.39	GO:0045732	positive regulation of protein catabolic process
0.35	GO:0006424	glutamyl-tRNA aminoacylation

0.61	GO:0030306	ADP-ribosylation factor binding
0.35	GO:0004818	glutamate-tRNA ligase activity
0.34	GO:0000049	tRNA binding
0.33	GO:0008270	zinc ion binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.71	GO:0030131	clathrin adaptor complex
0.56	GO:0005802	trans-Golgi network
0.46	GO:0030136	clathrin-coated vesicle
0.36	GO:0010008	endosome membrane
0.34	GO:0005769	early endosome
0.30	GO:0016021	integral component of membrane

0.35

EC:6.1.1.17

GO:0004818

tr|T1G629|T1G629_HELRO
Uncharacterized protein
Search

0.83	Rgs-gaip interacting protein gipc

0.65	GO:0014047	glutamate secretion
0.63	GO:1903846	positive regulation of cellular response to transforming growth factor beta stimulus
0.62	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process
0.61	GO:0043542	endothelial cell migration
0.60	GO:0090100	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
0.60	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway
0.60	GO:0048167	regulation of synaptic plasticity
0.60	GO:0032467	positive regulation of cytokinesis
0.57	GO:0031647	regulation of protein stability
0.56	GO:0007268	chemical synaptic transmission

0.60	GO:0017022	myosin binding
0.58	GO:0045296	cadherin binding
0.58	GO:0042802	identical protein binding
0.54	GO:0003779	actin binding
0.54	GO:0001965	G-protein alpha-subunit binding
0.53	GO:0005102	receptor binding
0.51	GO:0046983	protein dimerization activity
0.42	GO:0030165	PDZ domain binding
0.40	GO:0004957	prostaglandin E receptor activity
0.37	GO:0004707	MAP kinase activity

0.67	GO:0031982	vesicle
0.62	GO:0043198	dendritic shaft
0.61	GO:0043197	dendritic spine
0.57	GO:0098793	presynapse
0.55	GO:0005938	cell cortex
0.51	GO:0005829	cytosol
0.51	GO:0012505	endomembrane system
0.47	GO:0031090	organelle membrane
0.44	GO:0043229	intracellular organelle
0.42	GO:0005903	brush border

0.37	EC:2.7.11.24	GO:0004707
0.37	KEGG:R00162	GO:0004707

tr|T1G630|T1G630_HELRO
Uncharacterized protein
Search

CAPN9

0.72	Gill-specific calpain

0.64	GO:0007586	digestion
0.61	GO:0006508	proteolysis
0.42	GO:0051493	regulation of cytoskeleton organization
0.38	GO:0021785	branchiomotor neuron axon guidance
0.36	GO:0007420	brain development
0.34	GO:0051146	striated muscle cell differentiation
0.34	GO:0043066	negative regulation of apoptotic process
0.34	GO:0000768	syncytium formation by plasma membrane fusion
0.34	GO:0001824	blastocyst development
0.34	GO:0071230	cellular response to amino acid stimulus

0.82	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.67	GO:0005509	calcium ion binding

0.45	GO:0005622	intracellular
0.34	GO:0031143	pseudopodium
0.33	GO:0045121	membrane raft
0.33	GO:0012505	endomembrane system
0.32	GO:0043228	non-membrane-bounded organelle
0.32	GO:0044422	organelle part
0.32	GO:0043227	membrane-bounded organelle
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1G631|T1G631_HELRO
Uncharacterized protein
Search

0.62	GO:0042060	wound healing
0.45	GO:0051965	positive regulation of synapse assembly
0.38	GO:0007165	signal transduction
0.37	GO:0009058	biosynthetic process

0.43

GO:0016747

transferase activity, transferring acyl groups other than amino-acyl groups

0.41	GO:0005739	mitochondrion
0.40	GO:0005856	cytoskeleton
0.30	GO:0031224	intrinsic component of membrane

0.43

EC:2.3.1

GO:0016747

tr|T1G632|T1G632_HELRO
Uncharacterized protein
Search

0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity

0.61

GO:0005634

nucleus

tr|T1G633|T1G633_HELRO
Synaptotagmin 1b
Search

0.63	Synaptotagmin Ia

0.82	GO:0099643	signal release from synapse
0.82	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.76	GO:0006836	neurotransmitter transport
0.72	GO:0001505	regulation of neurotransmitter levels
0.69	GO:0051649	establishment of localization in cell
0.54	GO:1903861	positive regulation of dendrite extension
0.53	GO:0017158	regulation of calcium ion-dependent exocytosis
0.52	GO:0017156	calcium ion regulated exocytosis
0.52	GO:0097479	synaptic vesicle localization
0.51	GO:0099003	vesicle-mediated transport in synapse

0.81	GO:0005544	calcium-dependent phospholipid binding
0.52	GO:0050750	low-density lipoprotein particle receptor binding
0.51	GO:0019905	syntaxin binding
0.50	GO:0048306	calcium-dependent protein binding
0.46	GO:0005509	calcium ion binding
0.44	GO:0030276	clathrin binding
0.43	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.39	GO:0001786	phosphatidylserine binding
0.38	GO:0005516	calmodulin binding
0.38	GO:0008022	protein C-terminus binding

0.82	GO:0008021	synaptic vesicle
0.53	GO:0099501	exocytic vesicle membrane
0.52	GO:0031045	dense core granule
0.50	GO:0042734	presynaptic membrane
0.48	GO:0030424	axon
0.45	GO:0005794	Golgi apparatus
0.45	GO:0005829	cytosol
0.40	GO:0042584	chromaffin granule membrane
0.39	GO:0030054	cell junction
0.39	GO:0060076	excitatory synapse

tr|T1G634|T1G634_HELRO
Uncharacterized protein
Search

0.10	Putative metal ion transmembrane transporter

0.66	GO:0030001	metal ion transport
0.55	GO:0055085	transmembrane transport
0.49	GO:0006882	cellular zinc ion homeostasis
0.45	GO:0072511	divalent inorganic cation transport
0.35	GO:0034224	cellular response to zinc ion starvation
0.35	GO:0048026	positive regulation of mRNA splicing, via spliceosome
0.34	GO:0030509	BMP signaling pathway
0.34	GO:0016485	protein processing
0.34	GO:0001654	eye development
0.34	GO:0006888	ER to Golgi vesicle-mediated transport

0.68	GO:0046873	metal ion transmembrane transporter activity
0.46	GO:0072509	divalent inorganic cation transmembrane transporter activity
0.34	GO:0005537	mannose binding
0.34	GO:0070001	aspartic-type peptidase activity
0.33	GO:0004175	endopeptidase activity
0.33	GO:0016491	oxidoreductase activity
0.33	GO:0005515	protein binding
0.32	GO:0016874	ligase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0003677	DNA binding

0.43	GO:0005783	endoplasmic reticulum
0.42	GO:0005654	nucleoplasm
0.40	GO:0005887	integral component of plasma membrane
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0005794	Golgi apparatus
0.35	GO:0031984	organelle subcompartment
0.34	GO:0016323	basolateral plasma membrane
0.33	GO:0035102	PRC1 complex

0.33

GO:0016491

tr|T1G635|T1G635_HELRO
Uncharacterized protein
Search

0.30	Zinc finger MYM-type protein 1 (Fragment)

0.68

GO:0046983

protein dimerization activity

tr|T1G636|T1G636_HELRO
Uncharacterized protein
Search

SLC5A3

0.91	Low affinity sodium-glucose cotransporter

0.55	GO:0055085	transmembrane transport
0.44	GO:0015798	myo-inositol transport
0.41	GO:0006020	inositol metabolic process
0.39	GO:0043576	regulation of respiratory gaseous exchange
0.38	GO:0007422	peripheral nervous system development
0.38	GO:0015758	glucose transport
0.36	GO:0006814	sodium ion transport
0.35	GO:0106001	intestinal hexose absorption

0.57	GO:0022857	transmembrane transporter activity
0.33	GO:0004064	arylesterase activity

0.41

GO:0005887

integral component of plasma membrane

0.33

EC:3.1.1.2

GO:0004064

tr|T1G637|T1G637_HELRO
Uncharacterized protein
Search

tr|T1G638|T1G638_HELRO
Uncharacterized protein
Search

0.68	GO:0006470	protein dephosphorylation
0.42	GO:0044387	negative regulation of protein kinase activity by regulation of protein phosphorylation
0.42	GO:0051894	positive regulation of focal adhesion assembly
0.42	GO:0033137	negative regulation of peptidyl-serine phosphorylation
0.41	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.41	GO:0010634	positive regulation of epithelial cell migration
0.41	GO:0050921	positive regulation of chemotaxis
0.41	GO:0097193	intrinsic apoptotic signaling pathway
0.41	GO:0051496	positive regulation of stress fiber assembly
0.41	GO:0045927	positive regulation of growth

0.73	GO:0004722	protein serine/threonine phosphatase activity
0.51	GO:0046872	metal ion binding
0.37	GO:0008047	enzyme activator activity
0.37	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.36	GO:0047429	nucleoside-triphosphate diphosphatase activity
0.34	GO:0016301	kinase activity
0.34	GO:0003917	DNA topoisomerase type I activity
0.33	GO:0043168	anion binding
0.33	GO:1901265	nucleoside phosphate binding
0.33	GO:0036094	small molecule binding

0.38	GO:0005829	cytosol
0.36	GO:0043234	protein complex
0.36	GO:0005634	nucleus
0.36	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.37

GO:0036459

tr|T1G639|T1G639_HELRO
Uncharacterized protein
Search

RPL23

0.40	Ribosomal protein L23

0.58	GO:0043043	peptide biosynthetic process
0.54	GO:0044267	cellular protein metabolic process
0.52	GO:0010467	gene expression
0.51	GO:0009059	macromolecule biosynthetic process
0.47	GO:0072717	cellular response to actinomycin D
0.45	GO:2000059	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.45	GO:1901798	positive regulation of signal transduction by p53 class mediator
0.45	GO:1904667	negative regulation of ubiquitin protein ligase activity
0.45	GO:0071157	negative regulation of cell cycle arrest
0.45	GO:0071158	positive regulation of cell cycle arrest

0.61	GO:0003735	structural constituent of ribosome
0.46	GO:1990948	ubiquitin ligase inhibitor activity
0.46	GO:0001223	transcription coactivator binding
0.43	GO:0031625	ubiquitin protein ligase binding
0.42	GO:0070180	large ribosomal subunit rRNA binding

0.59	GO:0005840	ribosome
0.44	GO:0005730	nucleolus
0.41	GO:0044445	cytosolic part
0.40	GO:0005654	nucleoplasm
0.38	GO:0043234	protein complex
0.37	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.35	GO:0098556	cytoplasmic side of rough endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1G640|T1G640_HELRO
Uncharacterized protein
Search

ND4L

0.44	NADH-ubiquinone oxidoreductase chain 4L

0.66

GO:0042773

ATP synthesis coupled electron transport

0.65

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.61	GO:0005739	mitochondrion
0.30	GO:0044425	membrane part

0.65

GO:0008137

tr|T1G641|T1G641_HELRO
Uncharacterized protein
Search

0.61	GO:0045087	innate immune response
0.60	GO:0034138	toll-like receptor 3 signaling pathway
0.60	GO:0002756	MyD88-independent toll-like receptor signaling pathway
0.59	GO:0043330	response to exogenous dsRNA
0.59	GO:0032722	positive regulation of chemokine production
0.58	GO:0050729	positive regulation of inflammatory response
0.55	GO:0051607	defense response to virus
0.43	GO:0016310	phosphorylation

0.54	GO:0003725	double-stranded RNA binding
0.51	GO:0004888	transmembrane signaling receptor activity
0.45	GO:0016301	kinase activity

0.30

GO:0016020

membrane

tr|T1G642|T1G642_HELRO
Uncharacterized protein
Search

0.18	Aminopeptidase

0.61	GO:0006508	proteolysis
0.45	GO:0043171	peptide catabolic process
0.40	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I
0.39	GO:0008217	regulation of blood pressure
0.39	GO:0060395	SMAD protein signal transduction
0.36	GO:0030163	protein catabolic process
0.36	GO:0005977	glycogen metabolic process
0.36	GO:0060177	regulation of angiotensin metabolic process
0.35	GO:0050886	endocrine process
0.35	GO:0042445	hormone metabolic process

0.67	GO:0008237	metallopeptidase activity
0.67	GO:0004177	aminopeptidase activity
0.63	GO:0008270	zinc ion binding
0.41	GO:0042277	peptide binding
0.33	GO:0004252	serine-type endopeptidase activity

0.45	GO:0030287	cell wall-bounded periplasmic space
0.39	GO:0005576	extracellular region
0.38	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0030659	cytoplasmic vesicle membrane
0.37	GO:0005783	endoplasmic reticulum
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0031984	organelle subcompartment
0.34	GO:0005886	plasma membrane
0.32	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

0.67

EC:3.4.11

GO:0004177

tr|T1G643|T1G643_HELRO
Uncharacterized protein
Search

0.55	GO:0055085	transmembrane transport
0.44	GO:0015718	monocarboxylic acid transport

0.44	GO:0008028	monocarboxylic acid transmembrane transporter activity
0.33	GO:0015293	symporter activity
0.32	GO:0003676	nucleic acid binding

0.37

GO:0005887

integral component of plasma membrane

tr|T1G644|T1G644_HELRO
Uncharacterized protein
Search

SURF4

0.87	Surfeit gene 4

0.47	GO:0007030	Golgi organization
0.45	GO:0010638	positive regulation of organelle organization
0.36	GO:0040027	negative regulation of vulval development
0.36	GO:0034498	early endosome to Golgi transport
0.36	GO:0032527	protein exit from endoplasmic reticulum
0.36	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway
0.36	GO:0002119	nematode larval development
0.35	GO:1903364	positive regulation of cellular protein catabolic process
0.34	GO:0043312	neutrophil degranulation
0.34	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER

0.34	GO:0005515	protein binding
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.48	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.37	GO:0000139	Golgi membrane
0.37	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0035577	azurophil granule membrane
0.34	GO:0030133	transport vesicle
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1G645|T1G645_HELRO
Uncharacterized protein
Search

tr|T1G646|T1G646_HELRO
Uncharacterized protein
Search

tr|T1G647|T1G647_HELRO
Uncharacterized protein
Search

POLR2C

0.87	RNA polymerase II subunit C

0.56	GO:0006351	transcription, DNA-templated
0.37	GO:0006744	ubiquinone biosynthetic process
0.35	GO:0035019	somatic stem cell population maintenance
0.35	GO:0060964	regulation of gene silencing by miRNA
0.35	GO:0008543	fibroblast growth factor receptor signaling pathway
0.35	GO:0016073	snRNA metabolic process
0.35	GO:0050434	positive regulation of viral transcription
0.34	GO:0006283	transcription-coupled nucleotide-excision repair
0.34	GO:0000398	mRNA splicing, via spliceosome
0.34	GO:0006370	7-methylguanosine mRNA capping

0.68	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.66	GO:0046983	protein dimerization activity
0.49	GO:0003677	DNA binding

0.54	GO:0005665	DNA-directed RNA polymerase II, core complex
0.48	GO:0015630	microtubule cytoskeleton
0.47	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0003899

tr|T1G648|T1G648_HELRO
Uncharacterized protein
Search

SLC35B1

0.91	Solute carrier family 35 member B1

0.53	GO:0055085	transmembrane transport
0.43	GO:1901264	carbohydrate derivative transport
0.43	GO:0015931	nucleobase-containing compound transport
0.41	GO:0015711	organic anion transport
0.39	GO:0008643	carbohydrate transport

0.48

GO:0005459

UDP-galactose transmembrane transporter activity

0.46	GO:0030173	integral component of Golgi membrane
0.44	GO:0030176	integral component of endoplasmic reticulum membrane

tr|T1G649|T1G649_HELRO
Uncharacterized protein
Search

tr|T1G650|T1G650_HELRO
Uncharacterized protein
Search

0.39	GO:0051301	cell division
0.39	GO:0007049	cell cycle
0.39	GO:0034773	histone H4-K20 trimethylation
0.37	GO:2000045	regulation of G1/S transition of mitotic cell cycle
0.33	GO:0016310	phosphorylation

0.39	GO:0042799	histone methyltransferase activity (H4-K20 specific)
0.33	GO:0016301	kinase activity

0.61

GO:0005634

nucleus

tr|T1G651|T1G651_HELRO
Uncharacterized protein
Search

TFAP2D

0.71	Transcription factor AP-2-epsilon

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0061379	inferior colliculus development
0.56	GO:0010468	regulation of gene expression
0.52	GO:0043523	regulation of neuron apoptotic process
0.52	GO:1901215	negative regulation of neuron death
0.50	GO:0043066	negative regulation of apoptotic process
0.49	GO:1902680	positive regulation of RNA biosynthetic process
0.45	GO:0042127	regulation of cell proliferation
0.38	GO:0035213	clypeo-labral disc development

0.61	GO:0003700	DNA binding transcription factor activity
0.52	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.35	GO:0000987	proximal promoter sequence-specific DNA binding
0.35	GO:0003713	transcription coactivator activity
0.34	GO:0001046	core promoter sequence-specific DNA binding
0.34	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.48	GO:0005667	transcription factor complex
0.34	GO:0005813	centrosome
0.33	GO:0005794	Golgi apparatus
0.33	GO:0005829	cytosol
0.33	GO:0031974	membrane-enclosed lumen

tr|T1G652|T1G652_HELRO
Uncharacterized protein
Search

0.39	Aminopeptidase

0.61	GO:0006508	proteolysis
0.51	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I
0.50	GO:0008217	regulation of blood pressure
0.42	GO:0060177	regulation of angiotensin metabolic process
0.42	GO:0043171	peptide catabolic process
0.42	GO:0050886	endocrine process
0.40	GO:0042445	hormone metabolic process
0.39	GO:0051604	protein maturation
0.36	GO:0007267	cell-cell signaling
0.35	GO:0007165	signal transduction

0.67	GO:0008237	metallopeptidase activity
0.67	GO:0004177	aminopeptidase activity
0.63	GO:0008270	zinc ion binding
0.42	GO:0042277	peptide binding
0.34	GO:0004252	serine-type endopeptidase activity
0.34	GO:0104005	hijacked molecular function

0.45	GO:0005783	endoplasmic reticulum
0.42	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.41	GO:0031984	organelle subcompartment
0.39	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.39	GO:0009897	external side of plasma membrane
0.38	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.67

EC:3.4.11

GO:0004177

tr|T1G653|T1G653_HELRO
Uncharacterized protein
Search

0.45	40S ribosomal protein S15

0.58	GO:0043043	peptide biosynthetic process
0.54	GO:0044267	cellular protein metabolic process
0.52	GO:0010467	gene expression
0.51	GO:0009059	macromolecule biosynthetic process
0.44	GO:0000028	ribosomal small subunit assembly
0.40	GO:0043009	chordate embryonic development
0.38	GO:0000056	ribosomal small subunit export from nucleus
0.37	GO:0097421	liver regeneration
0.36	GO:0001649	osteoblast differentiation
0.36	GO:0016072	rRNA metabolic process

0.61	GO:0003735	structural constituent of ribosome
0.57	GO:0003723	RNA binding
0.34	GO:0005515	protein binding
0.32	GO:0003677	DNA binding

0.67	GO:0015935	small ribosomal subunit
0.43	GO:0022626	cytosolic ribosome
0.36	GO:0005925	focal adhesion
0.36	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

tr|T1G654|T1G654_HELRO
Uncharacterized protein
Search

tr|T1G655|T1G655_HELRO
Uncharacterized protein
Search

tr|T1G656|T1G656_HELRO
Uncharacterized protein
Search

0.43	GO:0051999	mannosyl-inositol phosphorylceramide biosynthetic process
0.39	GO:0097502	mannosylation
0.33	GO:0009405	pathogenesis
0.33	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.32	GO:0055114	oxidation-reduction process

0.40	GO:0016740	transferase activity
0.33	GO:0008408	3'-5' exonuclease activity
0.33	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.32	GO:0020037	heme binding
0.32	GO:0005506	iron ion binding
0.32	GO:0003676	nucleic acid binding

0.38	GO:0000139	Golgi membrane
0.37	GO:0033106	cis-Golgi network membrane
0.36	GO:0005802	trans-Golgi network
0.33	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

0.40

GO:0016740

tr|T1G657|T1G657_HELRO
Uncharacterized protein
Search

0.10	Putative Abl interactor

0.81	GO:0008154	actin polymerization or depolymerization
0.45	GO:0072499	photoreceptor cell axon guidance
0.45	GO:0060269	centripetally migrating follicle cell migration
0.45	GO:0042247	establishment of planar polarity of follicular epithelium
0.45	GO:1902284	neuron projection extension involved in neuron projection guidance
0.45	GO:0016203	muscle attachment
0.45	GO:0033627	cell adhesion mediated by integrin
0.45	GO:0022416	chaeta development
0.45	GO:0030032	lamellipodium assembly
0.45	GO:0021955	central nervous system neuron axonogenesis

0.42	GO:0045296	cadherin binding
0.34	GO:0050750	low-density lipoprotein particle receptor binding
0.34	GO:0016301	kinase activity
0.34	GO:0008201	heparin binding

0.45	GO:0031258	lamellipodium membrane
0.45	GO:0031209	SCAR complex
0.44	GO:0045178	basal part of cell
0.42	GO:0048471	perinuclear region of cytoplasm
0.42	GO:0099738	cell cortex region
0.42	GO:0098858	actin-based cell projection
0.33	GO:0005783	endoplasmic reticulum
0.30	GO:0016021	integral component of membrane

tr|T1G658|T1G658_HELRO
Uncharacterized protein
Search

0.57	Poly polymerase gamma

0.80	GO:0043631	RNA polyadenylation
0.76	GO:0031123	RNA 3'-end processing
0.40	GO:0048451	petal formation
0.40	GO:0006397	mRNA processing
0.39	GO:0048366	leaf development
0.38	GO:0008285	negative regulation of cell proliferation
0.37	GO:0033621	nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts
0.37	GO:0045824	negative regulation of innate immune response
0.36	GO:0043144	snoRNA processing

0.78	GO:0004652	polynucleotide adenylyltransferase activity
0.59	GO:0003723	RNA binding
0.52	GO:0032559	adenyl ribonucleotide binding
0.51	GO:0046872	metal ion binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005634	nucleus
0.36	GO:0031974	membrane-enclosed lumen
0.36	GO:0005829	cytosol
0.35	GO:0044446	intracellular organelle part
0.34	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.78

EC:2.7.7.19

GO:0004652

tr|T1G659|T1G659_HELRO
Uncharacterized protein
Search

tr|T1G660|T1G660_HELRO
Uncharacterized protein
Search

0.10	Aminopeptidase-like protein (Fragment)

0.64	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I
0.61	GO:0006508	proteolysis
0.57	GO:0008217	regulation of blood pressure
0.43	GO:0043171	peptide catabolic process
0.39	GO:0060177	regulation of angiotensin metabolic process
0.38	GO:0007267	cell-cell signaling
0.38	GO:0050886	endocrine process
0.37	GO:0042445	hormone metabolic process
0.36	GO:0051604	protein maturation
0.36	GO:0007165	signal transduction

0.70	GO:0004177	aminopeptidase activity
0.67	GO:0008237	metallopeptidase activity
0.63	GO:0008270	zinc ion binding
0.43	GO:0042277	peptide binding
0.35	GO:0005138	interleukin-6 receptor binding
0.33	GO:0004463	leukotriene-A4 hydrolase activity
0.33	GO:0010181	FMN binding
0.33	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.33	GO:0051287	NAD binding
0.33	GO:0051539	4 iron, 4 sulfur cluster binding

0.54	GO:0005783	endoplasmic reticulum
0.50	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.48	GO:0031984	organelle subcompartment
0.35	GO:0005886	plasma membrane
0.33	GO:0005576	extracellular region
0.32	GO:0043233	organelle lumen
0.30	GO:0016021	integral component of membrane

0.70	EC:3.4.11	GO:0004177
0.33	KEGG:R03057	GO:0004463

tr|T1G661|T1G661_HELRO
Uncharacterized protein
Search

0.64	GO:0015074	DNA integration
0.53	GO:1903506	regulation of nucleic acid-templated transcription
0.53	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.53	GO:0010468	regulation of gene expression
0.41	GO:1902679	negative regulation of RNA biosynthetic process
0.36	GO:0016310	phosphorylation

0.57	GO:0003700	DNA binding transcription factor activity
0.50	GO:0003676	nucleic acid binding
0.40	GO:0046983	protein dimerization activity
0.36	GO:0016301	kinase activity

0.57	GO:0005634	nucleus
0.46	GO:0031974	membrane-enclosed lumen
0.42	GO:0044446	intracellular organelle part
0.38	GO:0005737	cytoplasm

tr|T1G662|T1G662_HELRO
Uncharacterized protein
Search

tr|T1G663|T1G663_HELRO
Uncharacterized protein
Search

RNF7

0.95	Ring finger protein 7

0.54	GO:0045116	protein neddylation
0.48	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
0.48	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.37	GO:0021942	radial glia guided migration of Purkinje cell
0.36	GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress
0.36	GO:0021799	cerebral cortex radially oriented cell migration
0.36	GO:0008637	apoptotic mitochondrial changes
0.36	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.35	GO:0043066	negative regulation of apoptotic process
0.34	GO:0051775	response to redox state

0.63	GO:0008270	zinc ion binding
0.58	GO:0097602	cullin family protein binding
0.57	GO:0019788	NEDD8 transferase activity
0.48	GO:0061630	ubiquitin protein ligase activity
0.40	GO:0016874	ligase activity
0.34	GO:0031369	translation initiation factor binding
0.33	GO:0005507	copper ion binding
0.33	GO:0003743	translation initiation factor activity

0.59	GO:0031466	Cul5-RING ubiquitin ligase complex
0.50	GO:0031467	Cul7-RING ubiquitin ligase complex
0.50	GO:0043224	nuclear SCF ubiquitin ligase complex
0.50	GO:0031462	Cul2-RING ubiquitin ligase complex
0.48	GO:0080008	Cul4-RING E3 ubiquitin ligase complex
0.48	GO:0031463	Cul3-RING ubiquitin ligase complex
0.45	GO:0005654	nucleoplasm
0.44	GO:0005829	cytosol
0.34	GO:0005680	anaphase-promoting complex
0.34	GO:0016282	eukaryotic 43S preinitiation complex

0.40

GO:0016874

tr|T1G664|T1G664_HELRO
Uncharacterized protein
Search

POLR2C

0.88	RNA polymerase II subunit C

0.57	GO:0006351	transcription, DNA-templated
0.37	GO:0006744	ubiquinone biosynthetic process
0.35	GO:0035019	somatic stem cell population maintenance
0.35	GO:0060964	regulation of gene silencing by miRNA
0.35	GO:0008543	fibroblast growth factor receptor signaling pathway
0.35	GO:0016073	snRNA metabolic process
0.35	GO:0050434	positive regulation of viral transcription
0.34	GO:0006283	transcription-coupled nucleotide-excision repair
0.34	GO:0000398	mRNA splicing, via spliceosome
0.34	GO:0006370	7-methylguanosine mRNA capping

0.68	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.67	GO:0046983	protein dimerization activity
0.49	GO:0003677	DNA binding

0.54	GO:0005665	DNA-directed RNA polymerase II, core complex
0.48	GO:0015630	microtubule cytoskeleton
0.47	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0003899

tr|T1G665|T1G665_HELRO
Uncharacterized protein
Search

0.75	GO:1902358	sulfate transmembrane transport
0.39	GO:0015701	bicarbonate transport
0.39	GO:0019532	oxalate transport
0.39	GO:0051453	regulation of intracellular pH
0.38	GO:0042391	regulation of membrane potential
0.38	GO:1902476	chloride transmembrane transport

0.78	GO:0008271	secondary active sulfate transmembrane transporter activity
0.40	GO:0015106	bicarbonate transmembrane transporter activity
0.39	GO:0019531	oxalate transmembrane transporter activity
0.39	GO:0015301	anion:anion antiporter activity
0.38	GO:0005254	chloride channel activity

0.38	GO:0005886	plasma membrane
0.35	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

tr|T1G666|T1G666_HELRO
Uncharacterized protein
Search

0.55	Cyclic nucleotide-gated cation channel alpha-3

0.57	GO:0034220	ion transmembrane transport
0.43	GO:0071804	cellular potassium ion transport
0.41	GO:0042391	regulation of membrane potential
0.41	GO:0019935	cyclic-nucleotide-mediated signaling
0.35	GO:0034765	regulation of ion transmembrane transport
0.32	GO:0006468	protein phosphorylation

0.66	GO:0005216	ion channel activity
0.44	GO:0022836	gated channel activity
0.43	GO:0015079	potassium ion transmembrane transporter activity
0.34	GO:0004692	cGMP-dependent protein kinase activity

0.43	GO:0017071	intracellular cyclic nucleotide activated cation channel complex
0.39	GO:0005887	integral component of plasma membrane
0.33	GO:0005622	intracellular

0.34

EC:2.7.11.12

GO:0004692

tr|T1G667|T1G667_HELRO
Uncharacterized protein
Search

0.57	Poly polymerase gamma

0.80	GO:0043631	RNA polyadenylation
0.76	GO:0031123	RNA 3'-end processing
0.39	GO:0006397	mRNA processing
0.34	GO:0033621	nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts
0.34	GO:0043144	snoRNA processing

0.78	GO:0004652	polynucleotide adenylyltransferase activity
0.59	GO:0003723	RNA binding
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0046872	metal ion binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005634	nucleus
0.35	GO:0005829	cytosol
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0044446	intracellular organelle part
0.32	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.78

EC:2.7.7.19

GO:0004652

tr|T1G668|T1G668_HELRO
Uncharacterized protein
Search

0.78	GO:0001525	angiogenesis
0.74	GO:0043066	negative regulation of apoptotic process
0.56	GO:0051005	negative regulation of lipoprotein lipase activity
0.54	GO:0070328	triglyceride homeostasis
0.52	GO:2000351	regulation of endothelial cell apoptotic process
0.44	GO:0007596	blood coagulation
0.44	GO:0019216	regulation of lipid metabolic process
0.42	GO:0001666	response to hypoxia
0.41	GO:0051260	protein homooligomerization
0.40	GO:0010519	negative regulation of phospholipase activity

0.50	GO:0004857	enzyme inhibitor activity
0.47	GO:0042802	identical protein binding
0.39	GO:0005178	integrin binding
0.38	GO:0008083	growth factor activity
0.35	GO:0003723	RNA binding

0.70	GO:0005615	extracellular space
0.40	GO:0005578	proteinaceous extracellular matrix
0.38	GO:0005769	early endosome
0.38	GO:0009986	cell surface
0.37	GO:0005794	Golgi apparatus
0.30	GO:0016020	membrane

tr|T1G669|T1G669_HELRO
Uncharacterized protein
Search

tr|T1G670|T1G670_HELRO
Uncharacterized protein
Search

tr|T1G671|T1G671_HELRO
Uncharacterized protein
Search

TBP

0.60	TATA-binding protein 1

0.69	GO:0006352	DNA-templated transcription, initiation
0.51	GO:0006359	regulation of transcription by RNA polymerase III
0.50	GO:0006383	transcription by RNA polymerase III
0.50	GO:0006366	transcription by RNA polymerase II
0.47	GO:0065004	protein-DNA complex assembly
0.41	GO:0032501	multicellular organismal process
0.40	GO:0048856	anatomical structure development
0.40	GO:0010629	negative regulation of gene expression
0.39	GO:1903507	negative regulation of nucleic acid-templated transcription
0.39	GO:2000113	negative regulation of cellular macromolecule biosynthetic process

0.55	GO:0003677	DNA binding
0.55	GO:0001034	RNA polymerase III transcription factor activity, sequence-specific DNA binding
0.53	GO:0001093	TFIIB-class transcription factor binding
0.52	GO:0017162	aryl hydrocarbon receptor binding
0.51	GO:0001129	RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly
0.50	GO:0070491	repressing transcription factor binding
0.48	GO:0001067	regulatory region nucleic acid binding
0.45	GO:0019899	enzyme binding
0.34	GO:0008138	protein tyrosine/serine/threonine phosphatase activity

0.52	GO:0001940	male pronucleus
0.51	GO:0097550	transcriptional preinitiation complex
0.51	GO:0001939	female pronucleus
0.50	GO:0005719	nuclear euchromatin
0.50	GO:0005669	transcription factor TFIID complex
0.49	GO:0005672	transcription factor TFIIA complex
0.39	GO:0005737	cytoplasm
0.34	GO:0000120	RNA polymerase I transcription factor complex

0.34

GO:0008138

tr|T1G672|T1G672_HELRO
Uncharacterized protein
Search

0.62	GO:0010029	regulation of seed germination
0.56	GO:0016567	protein ubiquitination
0.41	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.39	GO:0045116	protein neddylation
0.39	GO:0016558	protein import into peroxisome matrix
0.35	GO:0006413	translational initiation
0.34	GO:0006281	DNA repair

0.57	GO:0008270	zinc ion binding
0.57	GO:0004842	ubiquitin-protein transferase activity
0.44	GO:0046982	protein heterodimerization activity
0.41	GO:0061659	ubiquitin-like protein ligase activity
0.41	GO:0016874	ligase activity
0.40	GO:0019788	NEDD8 transferase activity
0.40	GO:0097602	cullin family protein binding
0.37	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding

0.57	GO:0000151	ubiquitin ligase complex
0.38	GO:0005779	integral component of peroxisomal membrane
0.38	GO:0005634	nucleus
0.36	GO:0005852	eukaryotic translation initiation factor 3 complex

0.41	EC:6	GO:0016874
0.57	KEGG:R03876	GO:0004842

tr|T1G673|T1G673_HELRO
Uncharacterized protein
Search

0.77	Choline-phosphate cytidylyltransferase activity

0.49	GO:0009058	biosynthetic process
0.46	GO:0046470	phosphatidylcholine metabolic process
0.44	GO:0042067	establishment of ommatidial planar polarity
0.43	GO:0007476	imaginal disc-derived wing morphogenesis
0.43	GO:0008340	determination of adult lifespan
0.42	GO:0048477	oogenesis
0.40	GO:0006897	endocytosis
0.32	GO:0055114	oxidation-reduction process

0.53	GO:0016779	nucleotidyltransferase activity
0.33	GO:0051287	NAD binding
0.33	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

0.38	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.53

EC:2.7.7

GO:0016779

tr|T1G674|T1G674_HELRO
Uncharacterized protein
Search

0.94	Theromacin

0.72

GO:0006952

defense response

0.66

GO:0005576

extracellular region

tr|T1G675|T1G675_HELRO
Uncharacterized protein
Search

RABGGTA

0.76	Geranylgeranyltransferase type II

0.84	GO:0018344	protein geranylgeranylation
0.34	GO:0006461	protein complex assembly
0.34	GO:0043687	post-translational protein modification
0.34	GO:0007601	visual perception
0.33	GO:0042981	regulation of apoptotic process
0.33	GO:0006030	chitin metabolic process
0.33	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.33	GO:0006754	ATP biosynthetic process
0.33	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.32	GO:0071897	DNA biosynthetic process

0.83	GO:0008318	protein prenyltransferase activity
0.51	GO:0008270	zinc ion binding
0.39	GO:0017137	Rab GTPase binding
0.35	GO:0046982	protein heterodimerization activity
0.33	GO:0008061	chitin binding
0.33	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism
0.33	GO:0003684	damaged DNA binding
0.33	GO:0003887	DNA-directed DNA polymerase activity

0.84	GO:0005968	Rab-protein geranylgeranyltransferase complex
0.44	GO:0005654	nucleoplasm
0.34	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)
0.33	GO:0005829	cytosol
0.33	GO:0005576	extracellular region
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.83

EC:2.5.1

GO:0008318

tr|T1G676|T1G676_HELRO
Uncharacterized protein
Search

0.38	Ankyrin repeat domain-containing protein 16

0.54	GO:0034765	regulation of ion transmembrane transport
0.52	GO:0071805	potassium ion transmembrane transport
0.45	GO:0008213	protein alkylation
0.45	GO:0000395	mRNA 5'-splice site recognition
0.44	GO:0035725	sodium ion transmembrane transport
0.44	GO:0018195	peptidyl-arginine modification
0.43	GO:0000387	spliceosomal snRNP assembly
0.43	GO:0043414	macromolecule methylation
0.42	GO:0071918	urea transmembrane transport
0.42	GO:0006520	cellular amino acid metabolic process

0.56	GO:0005261	cation channel activity
0.53	GO:0022832	voltage-gated channel activity
0.52	GO:0046873	metal ion transmembrane transporter activity
0.52	GO:0022839	ion gated channel activity
0.51	GO:0008381	mechanosensitive ion channel activity
0.50	GO:0004067	asparaginase activity
0.49	GO:0015077	monovalent inorganic cation transmembrane transporter activity
0.44	GO:0030619	U1 snRNA binding
0.42	GO:0015204	urea transmembrane transporter activity
0.42	GO:0003729	mRNA binding

0.44	GO:0000243	commitment complex
0.44	GO:0071004	U2-type prespliceosome
0.43	GO:0005685	U1 snRNP
0.30	GO:0016020	membrane

0.50

EC:3.5.1.1

GO:0004067

tr|T1G677|T1G677_HELRO
Uncharacterized protein
Search

0.62	Serpin peptidase inhibitor clade B ovalbumin member 1

0.64	GO:0010951	negative regulation of endopeptidase activity
0.37	GO:0006508	proteolysis
0.36	GO:0090136	epithelial cell-cell adhesion
0.35	GO:0042270	protection from natural killer cell mediated cytotoxicity
0.34	GO:0002448	mast cell mediated immunity
0.34	GO:0033668	negative regulation by symbiont of host apoptotic process
0.34	GO:0071391	cellular response to estrogen stimulus
0.34	GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.34	GO:2000266	regulation of blood coagulation, intrinsic pathway
0.34	GO:0043066	negative regulation of apoptotic process

0.66	GO:0004867	serine-type endopeptidase inhibitor activity
0.37	GO:0008233	peptidase activity
0.34	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.34	GO:0002020	protease binding
0.33	GO:0004601	peroxidase activity
0.33	GO:0008201	heparin binding

0.73	GO:0005615	extracellular space
0.41	GO:0031012	extracellular matrix
0.35	GO:0005829	cytosol
0.33	GO:0005794	Golgi apparatus
0.33	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

0.37	EC:3.4	GO:0008233
0.33	KEGG:R03532	GO:0004601

tr|T1G678|T1G678_HELRO
Uncharacterized protein
Search

0.80	Regulator of G protein signaling 8

0.69	GO:0043547	positive regulation of GTPase activity
0.64	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.59	GO:0007186	G-protein coupled receptor signaling pathway
0.43	GO:0009968	negative regulation of signal transduction
0.39	GO:0002574	thrombocyte differentiation
0.39	GO:0048840	otolith development
0.39	GO:0048884	neuromast development
0.39	GO:0071599	otic vesicle development
0.38	GO:0009948	anterior/posterior axis specification
0.35	GO:0031018	endocrine pancreas development

0.70	GO:0005096	GTPase activator activity
0.53	GO:0001965	G-protein alpha-subunit binding
0.35	GO:0046872	metal ion binding
0.35	GO:0005516	calmodulin binding
0.34	GO:0003723	RNA binding
0.33	GO:0004871	signal transducer activity

0.50	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.47	GO:0005829	cytosol
0.36	GO:0032809	neuronal cell body membrane
0.35	GO:0043204	perikaryon
0.35	GO:0005634	nucleus
0.35	GO:0030425	dendrite
0.34	GO:1905360	GTPase complex
0.33	GO:0098797	plasma membrane protein complex
0.30	GO:0031224	intrinsic component of membrane

tr|T1G679|T1G679_HELRO
Uncharacterized protein
Search

0.10	glycine receptor subunit alpha-2-like

0.58	GO:0007165	signal transduction
0.57	GO:0034220	ion transmembrane transport
0.36	GO:0043052	thermotaxis
0.36	GO:0060255	regulation of macromolecule metabolic process
0.35	GO:0031323	regulation of cellular metabolic process
0.35	GO:0051171	regulation of nitrogen compound metabolic process
0.35	GO:0080090	regulation of primary metabolic process
0.35	GO:0009889	regulation of biosynthetic process
0.35	GO:0006821	chloride transport
0.34	GO:0016070	RNA metabolic process

0.70	GO:0005230	extracellular ligand-gated ion channel activity
0.66	GO:0004888	transmembrane signaling receptor activity
0.36	GO:0019182	histamine-gated chloride channel activity
0.35	GO:0140110	transcription regulator activity
0.34	GO:0003676	nucleic acid binding
0.34	GO:0005515	protein binding
0.34	GO:0140096	catalytic activity, acting on a protein
0.34	GO:0050825	ice binding
0.34	GO:0016301	kinase activity
0.34	GO:0008270	zinc ion binding

0.52	GO:0005886	plasma membrane
0.37	GO:0005634	nucleus
0.36	GO:0043235	receptor complex
0.35	GO:0034707	chloride channel complex
0.35	GO:0070013	intracellular organelle lumen
0.35	GO:0032040	small-subunit processome
0.34	GO:0043234	protein complex
0.34	GO:0031248	protein acetyltransferase complex
0.34	GO:1905368	peptidase complex
0.34	GO:0044446	intracellular organelle part

0.34

GO:0016773

tr|T1G680|T1G680_HELRO
Uncharacterized protein
Search

0.73	GO:0016567	protein ubiquitination
0.43	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.36	GO:0007049	cell cycle
0.33	GO:0008033	tRNA processing
0.32	GO:0006468	protein phosphorylation

0.33	GO:0004674	protein serine/threonine kinase activity
0.33	GO:0005515	protein binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.43	GO:0016604	nuclear body
0.32	GO:0005739	mitochondrion

0.33

GO:0004674

tr|T1G681|T1G681_HELRO
Uncharacterized protein
Search

tr|T1G682|T1G682_HELRO
Uncharacterized protein
Search

0.46	GO:2001141	regulation of RNA biosynthetic process
0.45	GO:0044719	regulation of imaginal disc-derived wing size
0.45	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.45	GO:0008039	synaptic target recognition
0.44	GO:0016203	muscle attachment
0.44	GO:0010468	regulation of gene expression
0.44	GO:0016319	mushroom body development
0.44	GO:0051253	negative regulation of RNA metabolic process
0.44	GO:0010558	negative regulation of macromolecule biosynthetic process
0.44	GO:0007298	border follicle cell migration

0.49	GO:0008270	zinc ion binding
0.46	GO:0046983	protein dimerization activity
0.43	GO:0003676	nucleic acid binding
0.43	GO:0046332	SMAD binding
0.42	GO:0003714	transcription corepressor activity
0.41	GO:0035091	phosphatidylinositol binding
0.38	GO:0003700	DNA binding transcription factor activity

0.49	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm

tr|T1G683|T1G683_HELRO
Uncharacterized protein
Search

0.48	GO:0060570	negative regulation of peptide hormone processing
0.47	GO:0010951	negative regulation of endopeptidase activity
0.41	GO:0006508	proteolysis
0.37	GO:0043066	negative regulation of apoptotic process
0.33	GO:0006779	porphyrin-containing compound biosynthetic process
0.32	GO:0055114	oxidation-reduction process

0.48	GO:0004867	serine-type endopeptidase inhibitor activity
0.44	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.41	GO:0008233	peptidase activity
0.33	GO:0070818	protoporphyrinogen oxidase activity
0.33	GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor

0.73	GO:0005615	extracellular space
0.30	GO:0016020	membrane

0.41

GO:0008233

tr|T1G684|T1G684_HELRO
Metalloendopeptidase
Search

0.23	Metalloendopeptidase

0.64	GO:0018996	molting cycle, collagen and cuticulin-based cuticle
0.58	GO:0006508	proteolysis
0.46	GO:0032447	protein urmylation
0.44	GO:0034227	tRNA thio-modification
0.44	GO:0002098	tRNA wobble uridine modification
0.40	GO:0042335	cuticle development
0.36	GO:0007591	molting cycle, chitin-based cuticle
0.36	GO:0007298	border follicle cell migration
0.36	GO:0010951	negative regulation of endopeptidase activity
0.36	GO:0001700	embryonic development via the syncytial blastoderm

0.67	GO:0004222	metalloendopeptidase activity
0.60	GO:0008270	zinc ion binding
0.41	GO:0000049	tRNA binding
0.40	GO:0016779	nucleotidyltransferase activity
0.37	GO:0005509	calcium ion binding
0.37	GO:0004867	serine-type endopeptidase inhibitor activity
0.36	GO:0070491	repressing transcription factor binding
0.36	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.36	GO:0035100	ecdysone binding
0.36	GO:0001225	RNA polymerase II transcription coactivator binding

0.41	GO:0005576	extracellular region
0.37	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm
0.35	GO:0034707	chloride channel complex
0.35	GO:0005667	transcription factor complex
0.35	GO:0005694	chromosome
0.35	GO:0030425	dendrite
0.34	GO:0043235	receptor complex
0.34	GO:0044446	intracellular organelle part
0.34	GO:0070013	intracellular organelle lumen

0.67	EC:3.4.24	GO:0004222
0.33	KEGG:R08689	GO:0046429

tr|T1G685|T1G685_HELRO
Uncharacterized protein
Search

0.37	Calcium dependent cysteine protease

0.51	GO:0055114	oxidation-reduction process
0.36	GO:0006508	proteolysis
0.34	GO:0006468	protein phosphorylation
0.33	GO:0006397	mRNA processing
0.32	GO:0002098	tRNA wobble uridine modification
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:0009059	macromolecule biosynthetic process

0.53	GO:0016491	oxidoreductase activity
0.41	GO:0008198	ferrous iron binding
0.36	GO:0008233	peptidase activity
0.36	GO:0030145	manganese ion binding
0.34	GO:0004674	protein serine/threonine kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003735	structural constituent of ribosome

0.34	GO:0005925	focal adhesion
0.34	GO:0044428	nuclear part
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0005737	cytoplasm
0.32	GO:0032991	macromolecular complex
0.32	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

0.53

GO:0016491

tr|T1G686|T1G686_HELRO
Uncharacterized protein
Search

0.88	Proto-oncogene serine/threonine-protein kinase pim-1

0.73	GO:0043066	negative regulation of apoptotic process
0.63	GO:0006468	protein phosphorylation
0.48	GO:0007346	regulation of mitotic cell cycle
0.48	GO:0008637	apoptotic mitochondrial changes
0.48	GO:0016239	positive regulation of macroautophagy
0.48	GO:0032091	negative regulation of protein binding
0.47	GO:0000082	G1/S transition of mitotic cell cycle
0.47	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.47	GO:0050821	protein stabilization
0.46	GO:0042127	regulation of cell proliferation

0.67	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0043024	ribosomal small subunit binding
0.36	GO:0005515	protein binding
0.36	GO:0030145	manganese ion binding
0.35	GO:0005249	voltage-gated potassium channel activity
0.34	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity

0.42	GO:0005829	cytosol
0.36	GO:0005730	nucleolus
0.35	GO:0008076	voltage-gated potassium channel complex
0.33	GO:0000139	Golgi membrane

0.67

GO:0004674

tr|T1G687|T1G687_HELRO
Guanine nucleotide-binding protein subunit gamma
Search

0.46	Guanine nucleotide-binding protein subunit gamma

0.71

GO:0007186

G-protein coupled receptor signaling pathway

0.64

GO:0004871

signal transducer activity

0.81	GO:1905360	GTPase complex
0.80	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.65	GO:0098797	plasma membrane protein complex

tr|T1G688|T1G688_HELRO
Uncharacterized protein
Search

0.70	TEA domain protein (Fragment)

0.80	GO:0035329	hippo signaling
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0006351	transcription, DNA-templated
0.48	GO:1902680	positive regulation of RNA biosynthetic process
0.45	GO:0031536	positive regulation of exit from mitosis
0.45	GO:0055059	asymmetric neuroblast division
0.42	GO:0030182	neuron differentiation
0.42	GO:0048568	embryonic organ development

0.61	GO:0003700	DNA binding transcription factor activity
0.52	GO:0003677	DNA binding
0.49	GO:0001085	RNA polymerase II transcription factor binding
0.47	GO:0001225	RNA polymerase II transcription coactivator binding
0.41	GO:0001067	regulatory region nucleic acid binding
0.35	GO:0004348	glucosylceramidase activity
0.34	GO:0046872	metal ion binding

0.57	GO:0005634	nucleus
0.46	GO:0005667	transcription factor complex
0.39	GO:0044446	intracellular organelle part
0.37	GO:0043233	organelle lumen

0.35

EC:3.2.1.45

GO:0004348

tr|T1G689|T1G689_HELRO
Uncharacterized protein
Search

0.83	GO:0007016	cytoskeletal anchoring at plasma membrane
0.70	GO:0007155	cell adhesion
0.51	GO:0033622	integrin activation
0.50	GO:0007044	cell-substrate junction assembly
0.48	GO:0030866	cortical actin cytoskeleton organization
0.47	GO:0007229	integrin-mediated signaling pathway
0.43	GO:0061386	closure of optic fissure
0.42	GO:0055013	cardiac muscle cell development
0.41	GO:0045214	sarcomere organization
0.36	GO:0030168	platelet activation

0.76	GO:0051015	actin filament binding
0.75	GO:0005200	structural constituent of cytoskeleton
0.51	GO:0017166	vinculin binding
0.50	GO:0030274	LIM domain binding
0.50	GO:0001786	phosphatidylserine binding
0.50	GO:0008483	transaminase activity
0.49	GO:0005178	integrin binding
0.48	GO:0045296	cadherin binding
0.46	GO:0035091	phosphatidylinositol binding

0.81	GO:0001726	ruffle
0.80	GO:0005925	focal adhesion
0.69	GO:0005856	cytoskeleton
0.36	GO:0031256	leading edge membrane
0.36	GO:0031253	cell projection membrane
0.35	GO:0070062	extracellular exosome
0.35	GO:0009986	cell surface
0.34	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.50

EC:2.6.1

GO:0008483

tr|T1G690|T1G690_HELRO
Uncharacterized protein
Search

0.58	Tetratricopeptide repeat protein 27 (Fragment)

0.64	GO:0006434	seryl-tRNA aminoacylation
0.55	GO:0031505	fungal-type cell wall organization
0.39	GO:0055114	oxidation-reduction process

0.64	GO:0004828	serine-tRNA ligase activity
0.47	GO:0032559	adenyl ribonucleotide binding
0.47	GO:0008144	drug binding
0.47	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0016491	oxidoreductase activity

0.45	GO:0005737	cytoplasm
0.41	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.64

EC:6.1.1.11

GO:0004828

tr|T1G691|T1G691_HELRO
Uncharacterized protein
Search

tr|T1G692|T1G692_HELRO
Uncharacterized protein
Search

0.54	GO:0010951	negative regulation of endopeptidase activity
0.44	GO:0051918	negative regulation of fibrinolysis
0.41	GO:0006508	proteolysis
0.40	GO:0030199	collagen fibril organization
0.39	GO:0002034	regulation of blood vessel diameter by renin-angiotensin
0.39	GO:0010757	negative regulation of plasminogen activation
0.39	GO:0071636	positive regulation of transforming growth factor beta production
0.39	GO:0032967	positive regulation of collagen biosynthetic process
0.38	GO:0048661	positive regulation of smooth muscle cell proliferation
0.38	GO:0051496	positive regulation of stress fiber assembly

0.55	GO:0004867	serine-type endopeptidase inhibitor activity
0.42	GO:0008233	peptidase activity
0.40	GO:0005518	collagen binding
0.38	GO:0002020	protease binding
0.37	GO:0042803	protein homodimerization activity
0.33	GO:0051082	unfolded protein binding

0.73	GO:0005615	extracellular space
0.37	GO:0009986	cell surface
0.36	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.35	GO:0098857	membrane microdomain
0.35	GO:0005783	endoplasmic reticulum
0.35	GO:0005829	cytosol
0.35	GO:0043234	protein complex
0.34	GO:0031012	extracellular matrix
0.34	GO:0031093	platelet alpha granule lumen
0.33	GO:1903561	extracellular vesicle

0.42

GO:0008233

tr|T1G693|T1G693_HELRO
Uncharacterized protein
Search

0.11	RNA-binding protein 12B (Fragment)

0.36

GO:0000381

regulation of alternative mRNA splicing, via spliceosome

0.59	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.34	GO:0005634	nucleus
0.33	GO:0019013	viral nucleocapsid
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0044425	membrane part

tr|T1G694|T1G694_HELRO
Uncharacterized protein
Search

0.72	chromatin-remodeling complex subunit ies6

0.77	GO:0006338	chromatin remodeling
0.36	GO:0080040	positive regulation of cellular response to phosphate starvation
0.36	GO:0060303	regulation of nucleosome density
0.36	GO:0016192	vesicle-mediated transport
0.35	GO:0016197	endosomal transport
0.33	GO:0006281	DNA repair
0.32	GO:0055114	oxidation-reduction process

0.35	GO:0043130	ubiquitin binding
0.32	GO:0003676	nucleic acid binding
0.32	GO:0016491	oxidoreductase activity

0.79	GO:0031011	Ino80 complex
0.35	GO:0000814	ESCRT II complex
0.34	GO:0030915	Smc5-Smc6 complex
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016491

tr|T1G695|T1G695_HELRO
Uncharacterized protein
Search

0.49	GO:0010951	negative regulation of endopeptidase activity
0.40	GO:0006508	proteolysis

0.50	GO:0004867	serine-type endopeptidase inhibitor activity
0.40	GO:0008233	peptidase activity
0.34	GO:0016740	transferase activity

0.73	GO:0005615	extracellular space
0.37	GO:0005783	endoplasmic reticulum
0.30	GO:0031224	intrinsic component of membrane

0.40

GO:0008233

tr|T1G696|T1G696_HELRO
Uncharacterized protein
Search

0.10	Ankyrin repeat domain containing protein

0.55	GO:0007165	signal transduction
0.37	GO:0016310	phosphorylation

0.51	GO:0004622	lysophospholipase activity
0.38	GO:0016301	kinase activity

0.30

GO:0031224

intrinsic component of membrane

0.51

EC:3.1.1.5

GO:0004622

tr|T1G697|T1G697_HELRO
Uncharacterized protein
Search

tr|T1G698|T1G698_HELRO
Uncharacterized protein
Search

0.50	GO:0010951	negative regulation of endopeptidase activity
0.41	GO:0006508	proteolysis
0.39	GO:0090136	epithelial cell-cell adhesion
0.37	GO:0046628	positive regulation of insulin receptor signaling pathway
0.37	GO:0090181	regulation of cholesterol metabolic process
0.37	GO:0090207	regulation of triglyceride metabolic process
0.37	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling
0.37	GO:0045721	negative regulation of gluconeogenesis
0.37	GO:0051055	negative regulation of lipid biosynthetic process
0.36	GO:0002244	hematopoietic progenitor cell differentiation

0.51	GO:0004867	serine-type endopeptidase inhibitor activity
0.42	GO:0008233	peptidase activity
0.35	GO:0002020	protease binding
0.35	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.34	GO:0005509	calcium ion binding
0.32	GO:0003676	nucleic acid binding
0.32	GO:0016740	transferase activity

0.73	GO:0005615	extracellular space
0.44	GO:0016607	nuclear speck
0.42	GO:0005829	cytosol
0.37	GO:1903561	extracellular vesicle
0.35	GO:0043202	lysosomal lumen
0.34	GO:0005886	plasma membrane
0.34	GO:0005730	nucleolus
0.30	GO:0016021	integral component of membrane

0.42

GO:0008233

tr|T1G699|T1G699_HELRO
Uncharacterized protein
Search

0.22	Splicing factor, arginine/serine-rich 7

0.63	GO:0008270	zinc ion binding
0.59	GO:0003723	RNA binding

0.35

GO:0005634

nucleus

tr|T1G6A0|T1G6A0_HELRO
Uncharacterized protein
Search

0.67	GO:0000956	nuclear-transcribed mRNA catabolic process
0.64	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.40	GO:0010607	negative regulation of cytoplasmic mRNA processing body assembly
0.38	GO:0008340	determination of adult lifespan
0.38	GO:0006397	mRNA processing
0.36	GO:0008334	histone mRNA metabolic process
0.36	GO:0071027	nuclear RNA surveillance
0.35	GO:0016075	rRNA catabolic process
0.34	GO:0055114	oxidation-reduction process

0.69	GO:0008409	5'-3' exonuclease activity
0.51	GO:0003676	nucleic acid binding
0.47	GO:0016896	exoribonuclease activity, producing 5'-phosphomonoesters
0.37	GO:0008408	3'-5' exonuclease activity
0.34	GO:0008270	zinc ion binding
0.34	GO:0000287	magnesium ion binding
0.34	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.33	GO:0016746	transferase activity, transferring acyl groups

0.43	GO:0005737	cytoplasm
0.41	GO:0005634	nucleus
0.36	GO:0035770	ribonucleoprotein granule
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.47

EC:3.1.13

GO:0016896

tr|T1G6A1|T1G6A1_HELRO
Uncharacterized protein
Search

FUCTA

0.67	Glycoprotein 3-alpha-L-fucosyltransferase A

0.81	GO:0036065	fucosylation
0.74	GO:0006486	protein glycosylation
0.44	GO:0007399	nervous system development

0.81	GO:0008417	fucosyltransferase activity
0.52	GO:0033932	1,3-alpha-L-fucosidase activity
0.49	GO:0140103	catalytic activity, acting on a glycoprotein

0.81	GO:0032580	Golgi cisterna membrane
0.48	GO:0005797	Golgi medial cisterna
0.30	GO:0031224	intrinsic component of membrane

0.81

GO:0008417

tr|T1G6A2|T1G6A2_HELRO
Uncharacterized protein
Search

POLR2F

0.93	RNA polymerase II subunit F

0.58	GO:0006351	transcription, DNA-templated
0.35	GO:0035019	somatic stem cell population maintenance
0.35	GO:0032481	positive regulation of type I interferon production
0.35	GO:0060964	regulation of gene silencing by miRNA
0.34	GO:0045815	positive regulation of gene expression, epigenetic
0.34	GO:0008543	fibroblast growth factor receptor signaling pathway
0.34	GO:0016073	snRNA metabolic process
0.34	GO:0050434	positive regulation of viral transcription
0.34	GO:0006283	transcription-coupled nucleotide-excision repair
0.34	GO:0000398	mRNA splicing, via spliceosome

0.70	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.55	GO:0003677	DNA binding
0.34	GO:0004427	inorganic diphosphatase activity
0.33	GO:0000287	magnesium ion binding

0.80	GO:0005665	DNA-directed RNA polymerase II, core complex
0.47	GO:0005736	DNA-directed RNA polymerase I complex
0.46	GO:0005666	DNA-directed RNA polymerase III complex
0.37	GO:0001650	fibrillar center
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.70	EC:2.7.7.6	GO:0003899
0.34	KEGG:R00004	GO:0004427

tr|T1G6A3|T1G6A3_HELRO
Uncharacterized protein
Search

tr|T1G6A4|T1G6A4_HELRO
Uncharacterized protein
Search

0.41	oxygen-dependent coproporphyrinogen-III oxidase

0.71	GO:0006779	porphyrin-containing compound biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.39	GO:0042168	heme metabolic process
0.39	GO:0046148	pigment biosynthetic process
0.37	GO:0042541	hemoglobin biosynthetic process
0.36	GO:0006397	mRNA processing
0.35	GO:0046501	protoporphyrinogen IX metabolic process
0.35	GO:0010288	response to lead ion
0.35	GO:0051597	response to methylmercury
0.35	GO:0017085	response to insecticide

0.78	GO:0004109	coproporphyrinogen oxidase activity
0.41	GO:0005212	structural constituent of eye lens
0.40	GO:0042803	protein homodimerization activity
0.34	GO:0003723	RNA binding
0.34	GO:0003909	DNA ligase activity

0.38	GO:0005829	cytosol
0.37	GO:0005739	mitochondrion
0.35	GO:0005634	nucleus
0.34	GO:0031970	organelle envelope lumen
0.33	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.78	EC:1.3.3.3	GO:0004109
0.78	KEGG:R03220	GO:0004109

tr|T1G6A5|T1G6A5_HELRO
Uncharacterized protein
Search

0.83	Glutamate receptor, ionotropic, AMPA 3a (Fragment)

0.80	GO:0060079	excitatory postsynaptic potential
0.77	GO:0035235	ionotropic glutamate receptor signaling pathway
0.59	GO:0034220	ion transmembrane transport
0.35	GO:0016573	histone acetylation
0.34	GO:0006182	cGMP biosynthetic process
0.33	GO:0006355	regulation of transcription, DNA-templated
0.33	GO:0006468	protein phosphorylation

0.82	GO:0005234	extracellularly glutamate-gated ion channel activity
0.77	GO:0004970	ionotropic glutamate receptor activity
0.44	GO:0099094	ligand-gated cation channel activity
0.35	GO:0005272	sodium channel activity
0.35	GO:0004402	histone acetyltransferase activity
0.35	GO:0098782	mechanosensitived potassium channel activity
0.35	GO:0003712	transcription cofactor activity
0.34	GO:0004383	guanylate cyclase activity
0.34	GO:0008270	zinc ion binding
0.33	GO:0004672	protein kinase activity

0.78	GO:0098794	postsynapse
0.77	GO:0097060	synaptic membrane
0.73	GO:0030054	cell junction
0.46	GO:0032281	AMPA glutamate receptor complex
0.34	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0005634	nucleus

0.35

GO:0004402

tr|T1G6A6|T1G6A6_HELRO
Uncharacterized protein
Search

tr|T1G6A7|T1G6A7_HELRO
Uncharacterized protein
Search

tr|T1G6A8|T1G6A8_HELRO
Uncharacterized protein
Search

0.12	putative transmembrane protein INAFM2

0.30

GO:0044425

membrane part

tr|T1G6A9|T1G6A9_HELRO
Uncharacterized protein
Search

0.77	Ionotropic glutamate receptor kainate 1B (Fragment)

0.77	GO:0035235	ionotropic glutamate receptor signaling pathway
0.77	GO:0060079	excitatory postsynaptic potential
0.58	GO:0006811	ion transport
0.50	GO:0055085	transmembrane transport
0.36	GO:0060025	regulation of synaptic activity
0.35	GO:0048899	anterior lateral line development
0.35	GO:0048915	posterior lateral line system development
0.34	GO:0014032	neural crest cell development
0.34	GO:0048701	embryonic cranial skeleton morphogenesis
0.34	GO:0007399	nervous system development

0.79	GO:0005234	extracellularly glutamate-gated ion channel activity
0.77	GO:0004970	ionotropic glutamate receptor activity
0.39	GO:0099094	ligand-gated cation channel activity
0.35	GO:0005272	sodium channel activity
0.35	GO:0098782	mechanosensitived potassium channel activity

0.75	GO:0045211	postsynaptic membrane
0.71	GO:0030054	cell junction
0.39	GO:0032281	AMPA glutamate receptor complex

tr|T1G6B0|T1G6B0_HELRO
Uncharacterized protein
Search

STAG1

0.81	Stromal antigen

0.70	GO:0016322	neuron remodeling
0.69	GO:0007130	synaptonemal complex assembly
0.65	GO:1901673	regulation of mitotic spindle assembly
0.58	GO:0006366	transcription by RNA polymerase II
0.57	GO:0045944	positive regulation of transcription by RNA polymerase II
0.46	GO:0007062	sister chromatid cohesion
0.43	GO:0000070	mitotic sister chromatid segregation
0.39	GO:0042073	intraciliary transport
0.37	GO:0051301	cell division

0.73	GO:0003682	chromatin binding
0.61	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.37	GO:0005515	protein binding
0.35	GO:0003676	nucleic acid binding

0.79	GO:0008278	cohesin complex
0.75	GO:0000922	spindle pole
0.68	GO:0000785	chromatin
0.65	GO:0000780	condensed nuclear chromosome, centromeric region
0.63	GO:0016363	nuclear matrix
0.61	GO:0072686	mitotic spindle
0.59	GO:0016604	nuclear body
0.38	GO:0005929	cilium
0.38	GO:0005829	cytosol
0.30	GO:0016020	membrane

tr|T1G6B1|T1G6B1_HELRO
Uncharacterized protein
Search

tr|T1G6B2|T1G6B2_HELRO
Uncharacterized protein
Search

0.52	GO:1905167	positive regulation of lysosomal protein catabolic process
0.52	GO:0097242	amyloid-beta clearance
0.51	GO:0002265	astrocyte activation involved in immune response
0.51	GO:1900223	positive regulation of amyloid-beta clearance
0.51	GO:0045056	transcytosis
0.50	GO:1904646	cellular response to amyloid-beta
0.49	GO:1903078	positive regulation of protein localization to plasma membrane
0.49	GO:0032092	positive regulation of protein binding
0.49	GO:0045807	positive regulation of endocytosis
0.47	GO:0010942	positive regulation of cell death

0.68	GO:0005509	calcium ion binding
0.53	GO:0016964	alpha-2 macroglobulin receptor activity
0.51	GO:0032050	clathrin heavy chain binding
0.51	GO:0034185	apolipoprotein binding
0.46	GO:0032403	protein complex binding
0.37	GO:0002020	protease binding
0.36	GO:0008196	vitellogenin receptor activity
0.35	GO:0030226	apolipoprotein receptor activity
0.35	GO:0005041	low-density lipoprotein receptor activity
0.34	GO:0015248	sterol transporter activity

0.48	GO:0016323	basolateral plasma membrane
0.47	GO:0005769	early endosome
0.47	GO:0043235	receptor complex
0.40	GO:0030135	coated vesicle
0.38	GO:0005905	clathrin-coated pit
0.38	GO:0030425	dendrite
0.37	GO:0030139	endocytic vesicle
0.37	GO:0005765	lysosomal membrane
0.36	GO:0043025	neuronal cell body
0.36	GO:0005794	Golgi apparatus

tr|T1G6B3|T1G6B3_HELRO
Uncharacterized protein
Search

0.78	ATP-dependent chromatin remodeler brahma

0.78	GO:0006338	chromatin remodeling
0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.35	GO:0043974	histone H3-K27 acetylation
0.35	GO:0035172	hemocyte proliferation
0.35	GO:0070983	dendrite guidance
0.35	GO:0043697	cell dedifferentiation
0.35	GO:0036335	intestinal stem cell homeostasis
0.35	GO:0007419	ventral cord development

0.80	GO:0042393	histone binding
0.61	GO:0016887	ATPase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0004386	helicase activity
0.36	GO:0003677	DNA binding
0.34	GO:0005509	calcium ion binding
0.33	GO:0046983	protein dimerization activity

0.82	GO:0016514	SWI/SNF complex
0.35	GO:0035060	brahma complex
0.34	GO:0016586	RSC-type complex
0.30	GO:0031224	intrinsic component of membrane

0.61

GO:0016887

tr|T1G6B4|T1G6B4_HELRO
Uncharacterized protein
Search

0.64	GO:0006278	RNA-dependent DNA biosynthetic process
0.37	GO:0007165	signal transduction
0.36	GO:0006108	malate metabolic process
0.36	GO:0006030	chitin metabolic process
0.36	GO:0035023	regulation of Rho protein signal transduction
0.35	GO:0065009	regulation of molecular function
0.34	GO:0019538	protein metabolic process
0.34	GO:0055114	oxidation-reduction process
0.34	GO:0005975	carbohydrate metabolic process
0.34	GO:0043412	macromolecule modification

0.65	GO:0003964	RNA-directed DNA polymerase activity
0.37	GO:0005201	extracellular matrix structural constituent
0.36	GO:0030060	L-malate dehydrogenase activity
0.36	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.36	GO:0008061	chitin binding
0.36	GO:0008270	zinc ion binding
0.36	GO:0004180	carboxypeptidase activity
0.36	GO:0005509	calcium ion binding
0.36	GO:0004930	G-protein coupled receptor activity
0.34	GO:0004672	protein kinase activity

0.35	GO:0005576	extracellular region
0.34	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.65

EC:2.7.7.49

GO:0003964

tr|T1G6B5|T1G6B5_HELRO
Uncharacterized protein
Search

tr|T1G6B6|T1G6B6_HELRO
Uncharacterized protein
Search

RBX1

0.74	RING-box protein 1 (inferred by orthology to a C. elegans protein)

0.48	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
0.48	GO:0045116	protein neddylation
0.47	GO:0006513	protein monoubiquitination
0.47	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.42	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.35	GO:0006293	nucleotide-excision repair, preincision complex stabilization
0.35	GO:0006294	nucleotide-excision repair, preincision complex assembly
0.35	GO:0010265	SCF complex assembly
0.35	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion
0.35	GO:0000717	nucleotide-excision repair, DNA duplex unwinding

0.63	GO:0008270	zinc ion binding
0.50	GO:0019788	NEDD8 transferase activity
0.49	GO:0097602	cullin family protein binding
0.47	GO:0034450	ubiquitin-ubiquitin ligase activity
0.45	GO:0031625	ubiquitin protein ligase binding
0.45	GO:0016874	ligase activity
0.43	GO:0008134	transcription factor binding
0.36	GO:0032403	protein complex binding
0.34	GO:0008190	eukaryotic initiation factor 4E binding

0.50	GO:0031467	Cul7-RING ubiquitin ligase complex
0.49	GO:0031462	Cul2-RING ubiquitin ligase complex
0.49	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex
0.48	GO:0031466	Cul5-RING ubiquitin ligase complex
0.48	GO:0019005	SCF ubiquitin ligase complex
0.48	GO:0031463	Cul3-RING ubiquitin ligase complex
0.48	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex
0.42	GO:0044428	nuclear part
0.41	GO:0031974	membrane-enclosed lumen
0.41	GO:0005829	cytosol

0.45

GO:0016874

tr|T1G6B7|T1G6B7_HELRO
Uncharacterized protein
Search

0.97	Torsin family 1 member A

0.70	GO:0072321	chaperone-mediated protein transport
0.70	GO:0006998	nuclear envelope organization
0.69	GO:0061077	chaperone-mediated protein folding
0.68	GO:0051084	'de novo' posttranslational protein folding
0.68	GO:0045104	intermediate filament cytoskeleton organization
0.66	GO:0048489	synaptic vesicle transport
0.63	GO:0031175	neuron projection development
0.58	GO:0007155	cell adhesion
0.55	GO:0007029	endoplasmic reticulum organization
0.51	GO:0051260	protein homooligomerization

0.58	GO:0008092	cytoskeletal protein binding
0.58	GO:0051082	unfolded protein binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0051787	misfolded protein binding
0.44	GO:0016887	ATPase activity
0.33	GO:0005179	hormone activity

0.74	GO:0005788	endoplasmic reticulum lumen
0.65	GO:0005635	nuclear envelope
0.61	GO:0045202	synapse
0.48	GO:0042406	extrinsic component of endoplasmic reticulum membrane
0.45	GO:0070382	exocytic vesicle
0.44	GO:0097458	neuron part
0.37	GO:0070062	extracellular exosome
0.37	GO:0032299	ribonuclease H2 complex
0.36	GO:0005829	cytosol
0.36	GO:0030141	secretory granule

0.44

GO:0016887

tr|T1G6B8|T1G6B8_HELRO
Uncharacterized protein
Search

0.48	Prohibitins and stomatins of the pid superfamily

0.40	GO:0097206	nephrocyte filtration
0.40	GO:1901585	regulation of acid-sensing ion channel activity
0.39	GO:0044829	positive regulation by host of viral genome replication
0.39	GO:0090314	positive regulation of protein targeting to membrane
0.37	GO:0051260	protein homooligomerization
0.35	GO:1905792	positive regulation of mechanosensory behavior
0.35	GO:1905789	positive regulation of detection of mechanical stimulus involved in sensory perception of touch
0.35	GO:0050976	detection of mechanical stimulus involved in sensory perception of touch
0.35	GO:0007638	mechanosensory behavior

0.37	GO:0070063	RNA polymerase binding
0.37	GO:0042803	protein homodimerization activity
0.34	GO:0015485	cholesterol binding

0.40	GO:0005887	integral component of plasma membrane
0.38	GO:0045121	membrane raft
0.37	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0005783	endoplasmic reticulum
0.36	GO:0005856	cytoskeleton
0.35	GO:0005917	nephrocyte diaphragm
0.35	GO:0005739	mitochondrion
0.35	GO:0032589	neuron projection membrane

tr|T1G6B9|T1G6B9_HELRO
Uncharacterized protein
Search

0.62	GO:0015074	DNA integration
0.44	GO:0006278	RNA-dependent DNA biosynthetic process
0.42	GO:0006508	proteolysis
0.37	GO:0006811	ion transport
0.36	GO:0061615	glycolytic process through fructose-6-phosphate
0.35	GO:0007165	signal transduction
0.34	GO:0055085	transmembrane transport
0.34	GO:0090305	nucleic acid phosphodiester bond hydrolysis

0.52	GO:0008270	zinc ion binding
0.50	GO:0003676	nucleic acid binding
0.45	GO:0070001	aspartic-type peptidase activity
0.45	GO:0003964	RNA-directed DNA polymerase activity
0.43	GO:0004175	endopeptidase activity
0.37	GO:0005216	ion channel activity
0.37	GO:0004888	transmembrane signaling receptor activity
0.36	GO:0003872	6-phosphofructokinase activity
0.34	GO:0004519	endonuclease activity
0.34	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups

0.38	GO:0005634	nucleus
0.36	GO:0019013	viral nucleocapsid
0.30	GO:0016020	membrane

0.45

EC:2.7.7.49

GO:0003964

tr|T1G6C0|T1G6C0_HELRO
Uncharacterized protein
Search

0.56	GO:0035881	amacrine cell differentiation
0.54	GO:0031016	pancreas development
0.51	GO:0061074	regulation of neural retina development
0.51	GO:0048384	retinoic acid receptor signaling pathway
0.50	GO:0010842	retina layer formation
0.49	GO:0030902	hindbrain development
0.49	GO:0048663	neuron fate commitment
0.49	GO:0045893	positive regulation of transcription, DNA-templated
0.47	GO:0035272	exocrine system development
0.46	GO:0009888	tissue development

0.68	GO:0046983	protein dimerization activity
0.50	GO:0070888	E-box binding
0.48	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.46	GO:0003682	chromatin binding
0.38	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.36	GO:0004634	phosphopyruvate hydratase activity
0.35	GO:0000287	magnesium ion binding

0.46	GO:0005667	transcription factor complex
0.36	GO:0005634	nucleus
0.36	GO:0000015	phosphopyruvate hydratase complex
0.33	GO:0043233	organelle lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.36

EC:4.2.1.11

GO:0004634

tr|T1G6C1|T1G6C1_HELRO
Uncharacterized protein
Search

0.25	Homeobox-leucine zipper protein HDG12 (Fragment)

0.65	GO:0090700	maintenance of plant organ identity
0.62	GO:0010091	trichome branching
0.59	GO:0048437	floral organ development
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.45	GO:0006351	transcription, DNA-templated

0.67	GO:0008289	lipid binding
0.65	GO:0043565	sequence-specific DNA binding
0.46	GO:0003700	DNA binding transcription factor activity

0.61

GO:0005634

nucleus

tr|T1G6C2|T1G6C2_HELRO
Uncharacterized protein
Search

tr|T1G6C3|T1G6C3_HELRO
Uncharacterized protein
Search

0.57	Zinc finger protein 92 (Fragment)

0.45	GO:1903506	regulation of nucleic acid-templated transcription
0.45	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.45	GO:0010468	regulation of gene expression
0.36	GO:0006351	transcription, DNA-templated
0.34	GO:0032259	methylation

0.51	GO:0003676	nucleic acid binding
0.43	GO:0046872	metal ion binding
0.39	GO:0003700	DNA binding transcription factor activity
0.34	GO:0008168	methyltransferase activity
0.33	GO:0005515	protein binding

0.42	GO:0005634	nucleus
0.35	GO:0005829	cytosol
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0044446	intracellular organelle part
0.33	GO:0019013	viral nucleocapsid
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016020	membrane

0.34

GO:0008168

tr|T1G6C4|T1G6C4_HELRO
Uncharacterized protein
Search

0.44

Lachesin

0.47	GO:0021740	principal sensory nucleus of trigeminal nerve development
0.46	GO:0002121	inter-male aggressive behavior
0.46	GO:0072102	glomerulus morphogenesis
0.45	GO:0021766	hippocampus development
0.44	GO:0033334	fin morphogenesis
0.44	GO:0007416	synapse assembly
0.44	GO:0001764	neuron migration
0.44	GO:0071711	basement membrane organization
0.43	GO:0007155	cell adhesion
0.43	GO:0048812	neuron projection morphogenesis

0.55	GO:0005509	calcium ion binding
0.40	GO:0005070	SH3/SH2 adaptor activity
0.35	GO:0097493	structural molecule activity conferring elasticity
0.35	GO:0051371	muscle alpha-actinin binding
0.35	GO:0008307	structural constituent of muscle
0.35	GO:0140096	catalytic activity, acting on a protein
0.34	GO:0030165	PDZ domain binding
0.34	GO:0051015	actin filament binding
0.34	GO:0016791	phosphatase activity
0.33	GO:0004872	receptor activity

0.48	GO:0005604	basement membrane
0.46	GO:0005938	cell cortex
0.45	GO:0030054	cell junction
0.45	GO:0043198	dendritic shaft
0.43	GO:0030424	axon
0.38	GO:0009986	cell surface
0.37	GO:0005886	plasma membrane
0.35	GO:0005859	muscle myosin complex
0.35	GO:0031430	M band
0.35	GO:0030018	Z disc

0.34

EC:3.1.3 EC:3.1.3.41

GO:0016791

tr|T1G6C5|T1G6C5_HELRO
Uncharacterized protein
Search

0.56	Transcription initiation factor TFIID subunit 3 (Fragment)

0.58	GO:0006413	translational initiation
0.50	GO:0051457	maintenance of protein location in nucleus
0.49	GO:0043433	negative regulation of DNA binding transcription factor activity
0.47	GO:0000122	negative regulation of transcription by RNA polymerase II
0.41	GO:0048634	regulation of muscle organ development
0.40	GO:0030097	hemopoiesis
0.36	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.36	GO:0006754	ATP biosynthetic process
0.35	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.35	GO:0006366	transcription by RNA polymerase II

0.65	GO:0046982	protein heterodimerization activity
0.58	GO:0003743	translation initiation factor activity
0.53	GO:0046872	metal ion binding
0.49	GO:0002039	p53 binding
0.39	GO:0044212	transcription regulatory region DNA binding
0.39	GO:0008134	transcription factor binding
0.38	GO:0045322	unmethylated CpG binding
0.36	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism
0.34	GO:0003924	GTPase activity
0.34	GO:0032550	purine ribonucleoside binding

0.78	GO:0005669	transcription factor TFIID complex
0.47	GO:0031965	nuclear membrane
0.39	GO:0048188	Set1C/COMPASS complex
0.36	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)
0.30	GO:0016021	integral component of membrane

0.33

GO:0008168

tr|T1G6C6|T1G6C6_HELRO
Uncharacterized protein
Search

0.79

GO:0060271

cilium assembly

0.83

GO:0097730

non-motile cilium

tr|T1G6C7|T1G6C7_HELRO
Uncharacterized protein
Search

tr|T1G6C8|T1G6C8_HELRO
Uncharacterized protein
Search

0.85	GO:1990504	dense core granule exocytosis
0.84	GO:0016079	synaptic vesicle exocytosis
0.44	GO:0045921	positive regulation of exocytosis
0.43	GO:0140029	exocytic process
0.42	GO:0009267	cellular response to starvation
0.40	GO:0043623	cellular protein complex assembly
0.35	GO:0006629	lipid metabolic process
0.35	GO:0035556	intracellular signal transduction
0.34	GO:0015031	protein transport
0.32	GO:1901575	organic substance catabolic process

0.38	GO:0004435	phosphatidylinositol phospholipase C activity
0.35	GO:0004871	signal transducer activity
0.34	GO:0008289	lipid binding
0.33	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.79	GO:0098793	presynapse
0.42	GO:0045211	postsynaptic membrane
0.41	GO:0031410	cytoplasmic vesicle
0.40	GO:0005654	nucleoplasm
0.35	GO:0012506	vesicle membrane
0.35	GO:0030054	cell junction
0.30	GO:0016021	integral component of membrane

0.38	EC:3.1.4.11	GO:0004435
0.38	KEGG:R03435	GO:0004435

tr|T1G6C9|T1G6C9_HELRO
Uncharacterized protein
Search

tr|T1G6D0|T1G6D0_HELRO
Uncharacterized protein
Search

0.10	Tigger transposable element-derived protein 1 (Fragment)

0.37	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.33	GO:0015074	DNA integration
0.33	GO:0006313	transposition, DNA-mediated
0.32	GO:0006351	transcription, DNA-templated

0.51	GO:0003676	nucleic acid binding
0.37	GO:0004519	endonuclease activity
0.34	GO:0046872	metal ion binding
0.33	GO:0004803	transposase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.32	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

tr|T1G6D1|T1G6D1_HELRO
Uncharacterized protein
Search

0.10	Dynein heavy chain, region 2

0.74	GO:0007018	microtubule-based movement
0.52	GO:0036158	outer dynein arm assembly
0.48	GO:0007368	determination of left/right symmetry
0.48	GO:0021670	lateral ventricle development
0.45	GO:0007507	heart development
0.40	GO:0030317	flagellated sperm motility
0.36	GO:0007605	sensory perception of sound
0.34	GO:0016539	intein-mediated protein splicing
0.33	GO:0006468	protein phosphorylation

0.75	GO:0003777	microtubule motor activity
0.59	GO:0016887	ATPase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0045503	dynein light chain binding
0.51	GO:0051959	dynein light intermediate chain binding
0.51	GO:0045505	dynein intermediate chain binding
0.33	GO:0004672	protein kinase activity

0.74	GO:0030286	dynein complex
0.54	GO:0044447	axoneme part
0.36	GO:0005874	microtubule
0.30	GO:0016021	integral component of membrane

0.59

GO:0016887

tr|T1G6D2|T1G6D2_HELRO
Uncharacterized protein
Search

0.11	Otoferlin (Fragment)

0.77	GO:0016079	synaptic vesicle exocytosis
0.43	GO:0010996	response to auditory stimulus
0.42	GO:0050885	neuromuscular process controlling balance
0.33	GO:0008643	carbohydrate transport
0.33	GO:1902600	hydrogen ion transmembrane transport

0.65	GO:0005509	calcium ion binding
0.34	GO:0005351	sugar:proton symporter activity
0.33	GO:0003676	nucleic acid binding

0.72	GO:0098793	presynapse
0.34	GO:0099501	exocytic vesicle membrane
0.34	GO:0016323	basolateral plasma membrane
0.34	GO:0031984	organelle subcompartment
0.34	GO:0030054	cell junction
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0044432	endoplasmic reticulum part
0.33	GO:0044431	Golgi apparatus part
0.30	GO:0031224	intrinsic component of membrane

tr|T1G6D3|T1G6D3_HELRO
Uncharacterized protein
Search

CAPZB

0.80	Capping actin protein of muscle Z-line beta subunit

0.84	GO:0051016	barbed-end actin filament capping
0.73	GO:0030036	actin cytoskeleton organization
0.51	GO:0051490	negative regulation of filopodium assembly
0.49	GO:0031115	negative regulation of microtubule polymerization
0.49	GO:0010591	regulation of lamellipodium assembly
0.49	GO:0090036	regulation of protein kinase C signaling
0.49	GO:0030032	lamellipodium assembly
0.48	GO:0048468	cell development
0.47	GO:0051146	striated muscle cell differentiation
0.46	GO:0048731	system development

0.74	GO:0003779	actin binding
0.47	GO:0048487	beta-tubulin binding
0.46	GO:0032403	protein complex binding
0.41	GO:0046982	protein heterodimerization activity
0.34	GO:0045296	cadherin binding

0.84	GO:0008290	F-actin capping protein complex
0.49	GO:0005737	cytoplasm
0.48	GO:0014704	intercalated disc
0.48	GO:0005903	brush border
0.47	GO:0097223	sperm part
0.47	GO:0030027	lamellipodium
0.45	GO:0099512	supramolecular fiber
0.44	GO:0097708	intracellular vesicle
0.42	GO:0012505	endomembrane system
0.42	GO:0005912	adherens junction

tr|T1G6D4|T1G6D4_HELRO
Uncharacterized protein
Search

0.47	GO:0006468	protein phosphorylation
0.46	GO:0007165	signal transduction
0.44	GO:0045087	innate immune response
0.44	GO:0002218	activation of innate immune response
0.43	GO:0001817	regulation of cytokine production
0.43	GO:0050729	positive regulation of inflammatory response
0.43	GO:0051223	regulation of protein transport
0.42	GO:0002237	response to molecule of bacterial origin
0.42	GO:0006954	inflammatory response
0.42	GO:0002791	regulation of peptide secretion

0.47	GO:0004672	protein kinase activity
0.45	GO:0004888	transmembrane signaling receptor activity
0.42	GO:0030554	adenyl nucleotide binding
0.42	GO:0097367	carbohydrate derivative binding
0.42	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0008144	drug binding
0.38	GO:0042497	triacyl lipopeptide binding
0.38	GO:0042562	hormone binding
0.38	GO:0009975	cyclase activity
0.37	GO:0005509	calcium ion binding

0.39	GO:0045335	phagocytic vesicle
0.39	GO:0098857	membrane microdomain
0.38	GO:0043235	receptor complex
0.38	GO:0012505	endomembrane system
0.37	GO:0030666	endocytic vesicle membrane
0.37	GO:0002177	manchette
0.36	GO:0031226	intrinsic component of plasma membrane
0.36	GO:0005764	lysosome
0.36	GO:0030426	growth cone
0.36	GO:0009986	cell surface

0.37	EC:4.6	GO:0016849
0.36	KEGG:R00842	GO:0004367

tr|T1G6D5|T1G6D5_HELRO
Uncharacterized protein
Search

0.10	zinc finger protein 2 homolog

0.47	GO:1903506	regulation of nucleic acid-templated transcription
0.47	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.47	GO:0010468	regulation of gene expression
0.36	GO:0006351	transcription, DNA-templated
0.35	GO:0040034	regulation of development, heterochronic
0.34	GO:0048523	negative regulation of cellular process
0.34	GO:0010558	negative regulation of macromolecule biosynthetic process
0.34	GO:0051172	negative regulation of nitrogen compound metabolic process
0.33	GO:0042127	regulation of cell proliferation
0.33	GO:0097264	self proteolysis

0.51	GO:0003676	nucleic acid binding
0.45	GO:0046872	metal ion binding
0.41	GO:0003700	DNA binding transcription factor activity
0.34	GO:0001223	transcription coactivator binding
0.34	GO:0030371	translation repressor activity
0.32	GO:0046983	protein dimerization activity

0.39	GO:0005622	intracellular
0.37	GO:0043227	membrane-bounded organelle
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0043230	extracellular organelle
0.33	GO:0044422	organelle part
0.33	GO:0005615	extracellular space
0.32	GO:0043228	non-membrane-bounded organelle

tr|T1G6D6|T1G6D6_HELRO
Uncharacterized protein
Search

tr|T1G6D7|T1G6D7_HELRO
Uncharacterized protein
Search

0.58	Zinc finger protein 629 (Fragment)

0.49	GO:1903506	regulation of nucleic acid-templated transcription
0.49	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.48	GO:0010468	regulation of gene expression
0.35	GO:0006351	transcription, DNA-templated
0.33	GO:0032259	methylation
0.32	GO:0098655	cation transmembrane transport

0.51	GO:0003676	nucleic acid binding
0.47	GO:0046872	metal ion binding
0.40	GO:0003700	DNA binding transcription factor activity
0.33	GO:0005261	cation channel activity
0.33	GO:0008168	methyltransferase activity
0.33	GO:0005515	protein binding

0.41	GO:0005622	intracellular
0.38	GO:0043227	membrane-bounded organelle
0.33	GO:0019013	viral nucleocapsid
0.32	GO:1990904	ribonucleoprotein complex
0.30	GO:0016020	membrane

0.33

GO:0008168

tr|T1G6D8|T1G6D8_HELRO
Uncharacterized protein
Search

tr|T1G6D9|T1G6D9_HELRO
Uncharacterized protein
Search

tr|T1G6E0|T1G6E0_HELRO
Uncharacterized protein
Search

0.50	Zinc finger MYM-type protein (Fragment)

0.68

GO:0046983

protein dimerization activity

tr|T1G6E1|T1G6E1_HELRO
Uncharacterized protein
Search

0.53	52 kDa repressor of the inhibitor of the protein kinase

0.56

GO:0016310

phosphorylation

0.68	GO:0046983	protein dimerization activity
0.59	GO:0016301	kinase activity

tr|T1G6E2|T1G6E2_HELRO
Uncharacterized protein
Search

0.55	Dynein heavy chain 8, axonemal

0.74	GO:0007018	microtubule-based movement
0.53	GO:0036158	outer dynein arm assembly
0.51	GO:0007368	determination of left/right symmetry
0.50	GO:0021670	lateral ventricle development
0.48	GO:0007507	heart development
0.40	GO:0030317	flagellated sperm motility
0.33	GO:0006468	protein phosphorylation

0.75	GO:0003777	microtubule motor activity
0.58	GO:0016887	ATPase activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0045503	dynein light chain binding
0.52	GO:0051959	dynein light intermediate chain binding
0.51	GO:0045505	dynein intermediate chain binding
0.33	GO:0004672	protein kinase activity

0.79	GO:0030286	dynein complex
0.56	GO:0044447	axoneme part
0.35	GO:0005874	microtubule
0.30	GO:0031224	intrinsic component of membrane

0.58

GO:0016887

tr|T1G6E3|T1G6E3_HELRO
Uncharacterized protein
Search

0.62	Myohemerythrin

0.41	GO:0015671	oxygen transport
0.34	GO:0046686	response to cadmium ion
0.33	GO:0035940	negative regulation of peptidase activity in other organism
0.33	GO:0035899	negative regulation of blood coagulation in other organism
0.33	GO:0007596	blood coagulation
0.32	GO:0006935	chemotaxis
0.32	GO:0007165	signal transduction

0.62	GO:0005506	iron ion binding
0.41	GO:0005344	oxygen carrier activity
0.32	GO:0030414	peptidase inhibitor activity
0.32	GO:0004871	signal transducer activity

0.32	GO:0005576	extracellular region
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|T1G6E4|T1G6E4_HELRO
Uncharacterized protein
Search

0.48	Polypeptide N-acetylgalactosaminyltransferase

0.72	GO:0006486	protein glycosylation
0.41	GO:0009312	oligosaccharide biosynthetic process
0.35	GO:0007286	spermatid development

0.68	GO:0030246	carbohydrate binding
0.64	GO:0016757	transferase activity, transferring glycosyl groups
0.40	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0005509	calcium ion binding

0.71	GO:0000139	Golgi membrane
0.36	GO:0005783	endoplasmic reticulum
0.30	GO:0031224	intrinsic component of membrane

0.64

GO:0016757

tr|T1G6E5|T1G6E5_HELRO
Uncharacterized protein
Search

0.75	Nicotinic acetylcholine receptor subunit type L

0.77	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.43	GO:0017085	response to insecticide
0.43	GO:0046716	muscle cell cellular homeostasis
0.42	GO:0007271	synaptic transmission, cholinergic
0.38	GO:0006812	cation transport
0.34	GO:0048630	skeletal muscle tissue growth
0.34	GO:0070050	neuron cellular homeostasis
0.34	GO:0003009	skeletal muscle contraction
0.34	GO:0019228	neuronal action potential

0.80	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0099600	transmembrane receptor activity
0.38	GO:0022850	serotonin-gated cation-selective channel activity
0.34	GO:0042166	acetylcholine binding
0.33	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
0.32	GO:0005509	calcium ion binding

0.77	GO:0045211	postsynaptic membrane
0.72	GO:0030054	cell junction
0.43	GO:0005892	acetylcholine-gated channel complex
0.34	GO:0031594	neuromuscular junction
0.33	GO:0009986	cell surface
0.33	GO:0005634	nucleus

0.33	EC:3.2.1.113	GO:0004571
0.33	KEGG:R05982 KEGG:R06722	GO:0004571

tr|T1G6E6|T1G6E6_HELRO
Uncharacterized protein
Search

0.61	GO:0060079	excitatory postsynaptic potential
0.56	GO:0034220	ion transmembrane transport
0.44	GO:0007229	integrin-mediated signaling pathway
0.35	GO:0007218	neuropeptide signaling pathway
0.35	GO:0007160	cell-matrix adhesion
0.35	GO:0034765	regulation of ion transmembrane transport
0.35	GO:0006313	transposition, DNA-mediated
0.35	GO:0007040	lysosome organization
0.34	GO:0015074	DNA integration
0.34	GO:0006814	sodium ion transport

0.69	GO:0005230	extracellular ligand-gated ion channel activity
0.64	GO:0004888	transmembrane signaling receptor activity
0.63	GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential
0.59	GO:0022835	transmitter-gated channel activity
0.58	GO:0140135	mechanosensitive cation channel activity
0.35	GO:0005248	voltage-gated sodium channel activity
0.35	GO:0046872	metal ion binding
0.35	GO:0016639	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
0.35	GO:0015035	protein disulfide oxidoreductase activity
0.34	GO:0022832	voltage-gated channel activity

0.61	GO:0045211	postsynaptic membrane
0.57	GO:0030054	cell junction
0.35	GO:0001518	voltage-gated sodium channel complex
0.35	GO:0008305	integrin complex
0.34	GO:0005765	lysosomal membrane
0.33	GO:0005634	nucleus

0.35

EC:1.4.1

GO:0016639

tr|T1G6E7|T1G6E7_HELRO
Uncharacterized protein
Search

0.64	Casein kinase I (inferred by orthology to a C. elegans protein)

0.63	GO:0006468	protein phosphorylation
0.46	GO:0007249	I-kappaB kinase/NF-kappaB signaling
0.46	GO:0018209	peptidyl-serine modification
0.43	GO:0007166	cell surface receptor signaling pathway
0.42	GO:0198738	cell-cell signaling by wnt
0.42	GO:0050793	regulation of developmental process
0.41	GO:0051128	regulation of cellular component organization
0.41	GO:0035509	negative regulation of myosin-light-chain-phosphatase activity
0.40	GO:0006897	endocytosis
0.40	GO:0071347	cellular response to interleukin-1

0.64	GO:0004672	protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0097110	scaffold protein binding
0.40	GO:0004871	signal transducer activity
0.39	GO:0019901	protein kinase binding
0.38	GO:0042803	protein homodimerization activity
0.38	GO:0046982	protein heterodimerization activity

0.40	GO:0005829	cytosol
0.38	GO:0005634	nucleus
0.35	GO:1902554	serine/threonine protein kinase complex
0.34	GO:0005813	centrosome
0.33	GO:0098857	membrane microdomain
0.33	GO:0035631	CD40 receptor complex
0.32	GO:0009898	cytoplasmic side of plasma membrane

0.34

GO:0004222

tr|T1G6E8|T1G6E8_HELRO
Uncharacterized protein
Search

tr|T1G6E9|T1G6E9_HELRO
Uncharacterized protein
Search

0.75	Serine/threonine-protein kinase A-Raf

0.63	GO:0006468	protein phosphorylation
0.61	GO:0035556	intracellular signal transduction
0.47	GO:0020021	immortalization of host cell
0.45	GO:0009968	negative regulation of signal transduction
0.45	GO:0043066	negative regulation of apoptotic process
0.44	GO:0000186	activation of MAPKK activity
0.44	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.43	GO:0035171	lamellocyte differentiation
0.43	GO:0008069	dorsal/ventral axis specification, ovarian follicular epithelium
0.43	GO:0046534	positive regulation of photoreceptor cell differentiation

0.75	GO:0005057	signal transducer activity, downstream of receptor
0.69	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0046872	metal ion binding
0.45	GO:0031434	mitogen-activated protein kinase kinase binding
0.40	GO:0046332	SMAD binding
0.33	GO:0042802	identical protein binding

0.44	GO:0005622	intracellular
0.38	GO:0043227	membrane-bounded organelle
0.34	GO:0044297	cell body
0.34	GO:0043005	neuron projection
0.33	GO:0005886	plasma membrane
0.33	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane

0.69

GO:0004674

tr|T1G6F0|T1G6F0_HELRO
Uncharacterized protein
Search

0.43	DNA-binding protein smubp-2

0.54	GO:0035279	mRNA cleavage involved in gene silencing by miRNA
0.41	GO:0048468	cell development
0.41	GO:0007283	spermatogenesis
0.40	GO:0022412	cellular process involved in reproduction in multicellular organism
0.40	GO:0003006	developmental process involved in reproduction
0.37	GO:0016358	dendrite development
0.37	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.36	GO:0030182	neuron differentiation
0.36	GO:0120036	plasma membrane bounded cell projection organization
0.36	GO:0009616	virus induced gene silencing

0.56	GO:0004386	helicase activity
0.40	GO:0003676	nucleic acid binding
0.40	GO:0008270	zinc ion binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0015238	drug transmembrane transporter activity
0.34	GO:0015297	antiporter activity
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding

0.50	GO:0000932	P-body
0.45	GO:0005829	cytosol
0.35	GO:0005615	extracellular space
0.30	GO:0016020	membrane

tr|T1G6F1|T1G6F1_HELRO
Uncharacterized protein
Search

PIP5K1C

0.82	Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha

0.75	GO:0046854	phosphatidylinositol phosphorylation
0.37	GO:0006909	phagocytosis
0.37	GO:0006661	phosphatidylinositol biosynthetic process
0.37	GO:0070527	platelet aggregation
0.37	GO:0006887	exocytosis
0.36	GO:0007016	cytoskeletal anchoring at plasma membrane
0.36	GO:0006935	chemotaxis
0.36	GO:0007409	axonogenesis
0.35	GO:0048488	synaptic vesicle endocytosis
0.35	GO:1990266	neutrophil migration

0.82	GO:0016307	phosphatidylinositol phosphate kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:1990147	talin binding
0.36	GO:0052812	phosphatidylinositol-3,4-bisphosphate 5-kinase activity

0.48	GO:0010008	endosome membrane
0.45	GO:0005654	nucleoplasm
0.45	GO:0005829	cytosol
0.39	GO:0001931	uropod
0.38	GO:0001891	phagocytic cup
0.38	GO:0032587	ruffle membrane
0.37	GO:0005925	focal adhesion
0.34	GO:0098793	presynapse

0.82

GO:0016307

tr|T1G6F2|T1G6F2_HELRO
Uncharacterized protein
Search

0.10	Adenylate/guanylate cyclase catalytic domain protein

0.78	GO:0006182	cGMP biosynthetic process
0.63	GO:0035556	intracellular signal transduction
0.47	GO:0006468	protein phosphorylation
0.40	GO:0045332	phospholipid translocation
0.38	GO:1904640	response to methionine
0.38	GO:0032026	response to magnesium ion
0.37	GO:1902074	response to salt
0.37	GO:0010226	response to lithium ion
0.37	GO:0050850	positive regulation of calcium-mediated signaling
0.37	GO:0007635	chemosensory behavior

0.78	GO:0004383	guanylate cyclase activity
0.52	GO:1901265	nucleoside phosphate binding
0.50	GO:0036094	small molecule binding
0.49	GO:0020037	heme binding
0.48	GO:0004672	protein kinase activity
0.43	GO:0008144	drug binding
0.43	GO:0097367	carbohydrate derivative binding
0.43	GO:0043168	anion binding
0.41	GO:0004016	adenylate cyclase activity
0.40	GO:0004012	phospholipid-translocating ATPase activity

0.45	GO:0005622	intracellular
0.38	GO:0043234	protein complex
0.36	GO:0005886	plasma membrane
0.33	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.78

GO:0004383

tr|T1G6F3|T1G6F3_HELRO
Uncharacterized protein
Search

0.37	GO:0016203	muscle attachment
0.37	GO:0007525	somatic muscle development
0.37	GO:0048741	skeletal muscle fiber development
0.37	GO:0045214	sarcomere organization
0.37	GO:0061053	somite development

0.79	GO:0002162	dystroglycan binding
0.74	GO:0003779	actin binding
0.58	GO:0008270	zinc ion binding

0.71	GO:0045211	postsynaptic membrane
0.67	GO:0030054	cell junction
0.62	GO:0005856	cytoskeleton
0.46	GO:0005737	cytoplasm
0.37	GO:0042383	sarcolemma
0.37	GO:0016010	dystrophin-associated glycoprotein complex

tr|T1G6F4|T1G6F4_HELRO
Uncharacterized protein
Search

tr|T1G6F5|T1G6F5_HELRO
Uncharacterized protein
Search

0.71	T-box transcription factor mls-1

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.45	GO:0042694	muscle cell fate specification
0.43	GO:0043282	pharyngeal muscle development
0.42	GO:0009791	post-embryonic development
0.41	GO:0042048	olfactory behavior
0.39	GO:0032880	regulation of protein localization
0.38	GO:0040011	locomotion

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.39	GO:0019899	enzyme binding
0.33	GO:0098772	molecular function regulator

0.61	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm
0.34	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

tr|T1G6F6|T1G6F6_HELRO
Uncharacterized protein
Search

0.47	GO:0007166	cell surface receptor signaling pathway
0.46	GO:0030198	extracellular matrix organization
0.46	GO:0007160	cell-matrix adhesion
0.44	GO:0007186	G-protein coupled receptor signaling pathway
0.40	GO:0007275	multicellular organism development
0.39	GO:0006260	DNA replication
0.39	GO:0048518	positive regulation of biological process
0.39	GO:0050793	regulation of developmental process
0.39	GO:0048869	cellular developmental process
0.38	GO:0030155	regulation of cell adhesion

0.70	GO:0005509	calcium ion binding
0.51	GO:0005201	extracellular matrix structural constituent
0.45	GO:0004888	transmembrane signaling receptor activity
0.40	GO:0030247	polysaccharide binding
0.38	GO:0004672	protein kinase activity
0.37	GO:0050840	extracellular matrix binding
0.37	GO:0005044	scavenger receptor activity
0.37	GO:0016504	peptidase activator activity
0.36	GO:0003682	chromatin binding
0.36	GO:0050431	transforming growth factor beta binding

0.53	GO:0031012	extracellular matrix
0.39	GO:0005634	nucleus
0.38	GO:0005615	extracellular space
0.38	GO:0035003	subapical complex
0.38	GO:0005912	adherens junction
0.37	GO:0031982	vesicle
0.36	GO:0009986	cell surface
0.36	GO:0005764	lysosome
0.36	GO:0043230	extracellular organelle
0.35	GO:0012505	endomembrane system

0.35

GO:0004222

tr|T1G6F7|T1G6F7_HELRO
Uncharacterized protein
Search

0.61	GO:0007165	signal transduction
0.60	GO:0034220	ion transmembrane transport
0.59	GO:0060078	regulation of postsynaptic membrane potential
0.58	GO:0007268	chemical synaptic transmission
0.38	GO:0042595	behavioral response to starvation
0.38	GO:0032000	positive regulation of fatty acid beta-oxidation
0.36	GO:0006821	chloride transport

0.76	GO:0005230	extracellular ligand-gated ion channel activity
0.70	GO:0004888	transmembrane signaling receptor activity
0.61	GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential
0.58	GO:0022835	transmitter-gated channel activity
0.57	GO:0140135	mechanosensitive cation channel activity
0.36	GO:0005254	chloride channel activity

0.59	GO:0045211	postsynaptic membrane
0.55	GO:0030054	cell junction
0.36	GO:0043025	neuronal cell body
0.30	GO:0016021	integral component of membrane

tr|T1G6F8|T1G6F8_HELRO
Uncharacterized protein
Search

0.59	GO:0008270	zinc ion binding
0.48	GO:0016874	ligase activity

0.43

GO:0005622

intracellular

0.48

GO:0016874

tr|T1G6F9|T1G6F9_HELRO
Uncharacterized protein
Search

0.76	GO:0007219	Notch signaling pathway
0.67	GO:0030154	cell differentiation
0.65	GO:0007275	multicellular organism development
0.63	GO:0050793	regulation of developmental process
0.49	GO:0048859	formation of anatomical boundary
0.49	GO:0097150	neuronal stem cell population maintenance
0.48	GO:0061351	neural precursor cell proliferation
0.48	GO:0009888	tissue development
0.47	GO:2001141	regulation of RNA biosynthetic process
0.47	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.70	GO:0005509	calcium ion binding
0.51	GO:0004872	receptor activity
0.42	GO:0003682	chromatin binding
0.35	GO:0050839	cell adhesion molecule binding
0.34	GO:0032403	protein complex binding
0.34	GO:0051059	NF-kappaB binding
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.33	GO:0004871	signal transducer activity
0.33	GO:0004713	protein tyrosine kinase activity
0.33	GO:0019899	enzyme binding

0.45	GO:0035003	subapical complex
0.44	GO:0009986	cell surface
0.43	GO:0005912	adherens junction
0.43	GO:0030139	endocytic vesicle
0.43	GO:0005770	late endosome
0.42	GO:0005764	lysosome
0.40	GO:0005634	nucleus
0.39	GO:0043235	receptor complex
0.37	GO:0043234	protein complex
0.37	GO:0070013	intracellular organelle lumen

0.34

GO:0032440

tr|T1G6G0|T1G6G0_HELRO
DNA-directed RNA polymerase subunit
Search

POLR2A

0.49	DNA-directed RNA polymerase subunit

0.71	GO:0006366	transcription by RNA polymerase II
0.43	GO:2000543	positive regulation of gastrulation
0.42	GO:0009299	mRNA transcription
0.41	GO:0051254	positive regulation of RNA metabolic process
0.41	GO:0007369	gastrulation
0.41	GO:0010628	positive regulation of gene expression
0.40	GO:0009792	embryo development ending in birth or egg hatching
0.39	GO:0010557	positive regulation of macromolecule biosynthetic process
0.39	GO:0031328	positive regulation of cellular biosynthetic process
0.38	GO:0043484	regulation of RNA splicing

0.70	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.55	GO:0003677	DNA binding
0.46	GO:0001067	regulatory region nucleic acid binding
0.37	GO:0031625	ubiquitin protein ligase binding
0.35	GO:0046872	metal ion binding
0.33	GO:0003723	RNA binding
0.33	GO:0003968	RNA-directed 5'-3' RNA polymerase activity
0.32	GO:0005524	ATP binding
0.32	GO:0016491	oxidoreductase activity

0.76	GO:0005665	DNA-directed RNA polymerase II, core complex
0.50	GO:0005719	nuclear euchromatin
0.42	GO:0035327	transcriptionally active chromatin
0.38	GO:0000974	Prp19 complex
0.36	GO:0005730	nucleolus
0.33	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.70

GO:0003899

tr|T1G6G1|T1G6G1_HELRO
Uncharacterized protein
Search

0.43	Filamin B, beta (Fragment)

0.64	GO:0007010	cytoskeleton organization
0.60	GO:0032507	maintenance of protein location in cell
0.56	GO:0030029	actin filament-based process
0.56	GO:0030154	cell differentiation
0.46	GO:0061061	muscle structure development
0.42	GO:0071346	cellular response to interferon-gamma
0.42	GO:0043588	skin development
0.41	GO:0008544	epidermis development
0.41	GO:0043578	nuclear matrix organization
0.41	GO:0014706	striated muscle tissue development

0.74	GO:0003779	actin binding
0.62	GO:0032403	protein complex binding
0.43	GO:0045296	cadherin binding
0.42	GO:0042802	identical protein binding
0.41	GO:0005521	lamin binding
0.39	GO:0030506	ankyrin binding
0.38	GO:0002162	dystroglycan binding
0.37	GO:0019899	enzyme binding
0.37	GO:0005509	calcium ion binding
0.36	GO:0008270	zinc ion binding

0.62	GO:0106083	nuclear membrane protein complex
0.62	GO:0034992	microtubule organizing center attachment site
0.44	GO:0032432	actin filament bundle
0.42	GO:0042641	actomyosin
0.42	GO:0005903	brush border
0.42	GO:0005924	cell-substrate adherens junction
0.42	GO:0045335	phagocytic vesicle
0.41	GO:0005829	cytosol
0.41	GO:0030017	sarcomere
0.40	GO:0031965	nuclear membrane

tr|T1G6G2|T1G6G2_HELRO
Uncharacterized protein
Search

0.64	Molybdenum cofactor synthesis protein cinnamon

0.44	GO:0042774	plasma membrane ATP synthesis coupled electron transport
0.40	GO:0008535	respiratory chain complex IV assembly
0.39	GO:1902600	hydrogen ion transmembrane transport
0.35	GO:0015031	protein transport

0.39	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.39	GO:0015002	heme-copper terminal oxidase activity
0.39	GO:0015078	hydrogen ion transmembrane transporter activity
0.38	GO:0005507	copper ion binding
0.38	GO:0009055	electron transfer activity
0.35	GO:0005515	protein binding
0.34	GO:0003723	RNA binding

0.61	GO:0005739	mitochondrion
0.40	GO:0031970	organelle envelope lumen
0.39	GO:0072492	host cell mitochondrial intermembrane space
0.35	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.39

EC:1.9.3

GO:0016676

tr|T1G6G3|T1G6G3_HELRO
Uncharacterized protein
Search

0.41	Glycoside hydrolase subgroup catalytic core

0.60	GO:0005975	carbohydrate metabolic process
0.33	GO:0006629	lipid metabolic process

0.66	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.34	GO:0016298	lipase activity
0.33	GO:0005509	calcium ion binding

0.34	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

0.66

EC:3.2.1

GO:0004553

tr|T1G6G4|T1G6G4_HELRO
Uncharacterized protein
Search

0.52	GO:0021891	olfactory bulb interneuron development
0.50	GO:0035137	hindlimb morphogenesis
0.50	GO:0045879	negative regulation of smoothened signaling pathway
0.50	GO:0035136	forelimb morphogenesis
0.43	GO:0006366	transcription by RNA polymerase II
0.40	GO:0060290	transdifferentiation
0.39	GO:0014016	neuroblast differentiation
0.39	GO:0048333	mesodermal cell differentiation
0.39	GO:0007165	signal transduction
0.38	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.51	GO:0003676	nucleic acid binding
0.39	GO:0003700	DNA binding transcription factor activity
0.35	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding

0.40	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|T1G6G5|T1G6G5_HELRO
Uncharacterized protein
Search

0.64	GO:0007219	Notch signaling pathway
0.56	GO:0030154	cell differentiation
0.56	GO:0007275	multicellular organism development
0.54	GO:0050793	regulation of developmental process
0.37	GO:0060255	regulation of macromolecule metabolic process
0.37	GO:0080090	regulation of primary metabolic process
0.37	GO:0031323	regulation of cellular metabolic process
0.37	GO:0051171	regulation of nitrogen compound metabolic process
0.37	GO:0009889	regulation of biosynthetic process
0.36	GO:0007155	cell adhesion

0.70	GO:0005509	calcium ion binding
0.40	GO:0004872	receptor activity
0.36	GO:0004867	serine-type endopeptidase inhibitor activity
0.35	GO:0004252	serine-type endopeptidase activity
0.35	GO:0005112	Notch binding
0.34	GO:0008061	chitin binding
0.34	GO:0004871	signal transducer activity
0.33	GO:0008270	zinc ion binding
0.33	GO:0005201	extracellular matrix structural constituent
0.33	GO:0016504	peptidase activator activity

0.36	GO:0005576	extracellular region
0.32	GO:0008305	integrin complex

0.35

GO:0004252

tr|T1G6G6|T1G6G6_HELRO
Uncharacterized protein
Search

tr|T1G6G7|T1G6G7_HELRO
Uncharacterized protein
Search

0.45	Cytosolic purine 5'-nucleotidase

0.37

GO:0016311

dephosphorylation

0.53	GO:0046872	metal ion binding
0.38	GO:0008253	5'-nucleotidase activity

0.30

GO:0031224

intrinsic component of membrane

0.38

EC:3.1.3.5

GO:0008253

tr|T1G6G8|T1G6G8_HELRO
Uncharacterized protein
Search

0.43	Transcription factor che-1 (inferred by orthology to a C. elegans protein)

0.40	GO:1904640	response to methionine
0.39	GO:0032026	response to magnesium ion
0.39	GO:1902074	response to salt
0.39	GO:0010226	response to lithium ion
0.39	GO:0010446	response to alkaline pH
0.39	GO:0050920	regulation of chemotaxis
0.39	GO:0030182	neuron differentiation
0.39	GO:0045944	positive regulation of transcription by RNA polymerase II
0.38	GO:0007635	chemosensory behavior
0.38	GO:0032103	positive regulation of response to external stimulus

0.51	GO:0003676	nucleic acid binding
0.35	GO:0046872	metal ion binding
0.35	GO:0005118	sevenless binding
0.34	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.33	GO:0004930	G-protein coupled receptor activity

0.36	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|T1G6G9|T1G6G9_HELRO
Uncharacterized protein
Search

tr|T1G6H0|T1G6H0_HELRO
Uncharacterized protein
Search

0.62	GO:0007219	Notch signaling pathway
0.57	GO:0030154	cell differentiation
0.56	GO:0007275	multicellular organism development
0.53	GO:0050793	regulation of developmental process
0.50	GO:0045967	negative regulation of growth rate
0.48	GO:0046849	bone remodeling
0.47	GO:0046579	positive regulation of Ras protein signal transduction
0.47	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.47	GO:0007050	cell cycle arrest
0.46	GO:0009653	anatomical structure morphogenesis

0.70	GO:0005509	calcium ion binding
0.50	GO:0004872	receptor activity
0.35	GO:0004871	signal transducer activity
0.35	GO:0102567	phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
0.35	GO:0102568	phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
0.34	GO:0004623	phospholipase A2 activity
0.34	GO:0005112	Notch binding
0.34	GO:0008061	chitin binding
0.34	GO:0030247	polysaccharide binding
0.34	GO:0004867	serine-type endopeptidase inhibitor activity

0.45	GO:0043235	receptor complex
0.44	GO:0009986	cell surface
0.43	GO:0005913	cell-cell adherens junction
0.43	GO:0005902	microvillus
0.42	GO:0005654	nucleoplasm
0.42	GO:0005887	integral component of plasma membrane
0.38	GO:0043234	protein complex
0.34	GO:0005576	extracellular region
0.33	GO:0001917	photoreceptor inner segment
0.33	GO:0016324	apical plasma membrane

0.34

EC:3.1.1.4

GO:0004623

tr|T1G6H1|T1G6H1_HELRO
Uncharacterized protein
Search

DIAPH3

0.89	Diaphanous

0.73	GO:0030036	actin cytoskeleton organization
0.64	GO:0097435	supramolecular fiber organization
0.54	GO:0051258	protein polymerization
0.48	GO:0007049	cell cycle
0.46	GO:0007276	gamete generation
0.45	GO:0071420	cellular response to histamine
0.44	GO:0035372	protein localization to microtubule
0.43	GO:0051279	regulation of release of sequestered calcium ion into cytosol
0.42	GO:0032886	regulation of microtubule-based process
0.41	GO:0051493	regulation of cytoskeleton organization

0.76	GO:0017048	Rho GTPase binding
0.74	GO:0003779	actin binding
0.50	GO:0045296	cadherin binding
0.43	GO:0044325	ion channel binding
0.34	GO:0005102	receptor binding
0.33	GO:0008017	microtubule binding
0.33	GO:0030545	receptor regulator activity
0.32	GO:0003723	RNA binding
0.32	GO:0003924	GTPase activity
0.32	GO:0005525	GTP binding

0.42	GO:0072686	mitotic spindle
0.36	GO:0005634	nucleus
0.36	GO:0005829	cytosol
0.35	GO:0101003	ficolin-1-rich granule membrane
0.34	GO:0032587	ruffle membrane
0.34	GO:0070013	intracellular organelle lumen
0.34	GO:0005783	endoplasmic reticulum
0.34	GO:0005884	actin filament
0.34	GO:0005815	microtubule organizing center
0.32	GO:0005576	extracellular region

tr|T1G6H2|T1G6H2_HELRO
Uncharacterized protein
Search

SPTSSA

0.96	Small subunit of serine palmitoyltransferase A

0.58	GO:0006665	sphingolipid metabolic process
0.51	GO:0046467	membrane lipid biosynthetic process
0.44	GO:0043604	amide biosynthetic process
0.42	GO:1901566	organonitrogen compound biosynthetic process
0.37	GO:1904220	regulation of serine C-palmitoyltransferase activity
0.36	GO:0007029	endoplasmic reticulum organization

0.64	GO:0004758	serine C-palmitoyltransferase activity
0.34	GO:0005515	protein binding

0.64	GO:0017059	serine C-palmitoyltransferase complex
0.30	GO:0031224	intrinsic component of membrane

0.64	EC:2.3.1.50	GO:0004758
0.64	KEGG:R01281	GO:0004758

tr|T1G6H3|T1G6H3_HELRO
Uncharacterized protein
Search

0.69	GO:0006457	protein folding
0.40	GO:0010043	response to zinc ion
0.39	GO:0046686	response to cadmium ion
0.35	GO:0043461	proton-transporting ATP synthase complex assembly
0.35	GO:0070084	protein initiator methionine removal
0.34	GO:0035335	peptidyl-tyrosine dephosphorylation
0.34	GO:0016569	covalent chromatin modification
0.33	GO:0006508	proteolysis

0.71	GO:0051082	unfolded protein binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0044183	protein binding involved in protein folding
0.34	GO:0070006	metalloaminopeptidase activity
0.34	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.34	GO:0004725	protein tyrosine phosphatase activity
0.33	GO:0046872	metal ion binding

0.48	GO:0005737	cytoplasm
0.48	GO:0101031	chaperone complex
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.34

GO:0008138

tr|T1G6H4|T1G6H4_HELRO
Uncharacterized protein
Search

0.39	BMP-2-inducible protein kinase

0.63	GO:0006468	protein phosphorylation
0.45	GO:2000369	regulation of clathrin-dependent endocytosis
0.41	GO:0045747	positive regulation of Notch signaling pathway
0.40	GO:0032259	methylation
0.39	GO:0008356	asymmetric cell division
0.39	GO:0048813	dendrite morphogenesis
0.35	GO:0050821	protein stabilization
0.34	GO:0032880	regulation of protein localization
0.34	GO:0016192	vesicle-mediated transport
0.34	GO:0000245	spliceosomal complex assembly

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0035612	AP-2 adaptor complex binding
0.41	GO:0051425	PTB domain binding
0.40	GO:0008168	methyltransferase activity
0.37	GO:0046872	metal ion binding
0.36	GO:0005112	Notch binding
0.33	GO:0070403	NAD+ binding

0.39	GO:0043025	neuronal cell body
0.39	GO:0030425	dendrite
0.39	GO:0030424	axon
0.35	GO:0031982	vesicle
0.34	GO:0005737	cytoplasm
0.33	GO:0048475	coated membrane
0.33	GO:0098805	whole membrane
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0012505	endomembrane system
0.32	GO:0098796	membrane protein complex

0.40

GO:0008168

tr|T1G6H6|T1G6H6_HELRO
Uncharacterized protein
Search

ATRX

0.77	Alpha thalassemia/mental retardation syndrome X-linked

0.43	GO:0035128	post-embryonic forelimb morphogenesis
0.43	GO:1901580	regulation of telomeric RNA transcription from RNA pol II promoter
0.43	GO:0072711	cellular response to hydroxyurea
0.42	GO:0060009	Sertoli cell development
0.42	GO:0010571	positive regulation of nuclear cell cycle DNA replication
0.42	GO:0072520	seminiferous tubule development
0.42	GO:0070198	protein localization to chromosome, telomeric region
0.42	GO:0030330	DNA damage response, signal transduction by p53 class mediator
0.42	GO:0000212	meiotic spindle organization
0.42	GO:0032206	positive regulation of telomere maintenance

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0042393	histone binding
0.40	GO:0003682	chromatin binding
0.39	GO:0070087	chromo shadow domain binding
0.39	GO:0015616	DNA translocase activity
0.38	GO:0140034	methylation-dependent protein binding

0.42	GO:0031933	telomeric heterochromatin
0.42	GO:0031618	nuclear pericentric heterochromatin
0.41	GO:0016605	PML body
0.41	GO:0000784	nuclear chromosome, telomeric region
0.40	GO:0000780	condensed nuclear chromosome, centromeric region
0.39	GO:1990707	nuclear subtelomeric heterochromatin
0.37	GO:0070603	SWI/SNF superfamily-type complex

tr|T1G6H7|T1G6H7_HELRO
Uncharacterized protein
Search

0.37	MORN repeat protein

0.51	GO:1901076	positive regulation of engulfment of apoptotic cell
0.42	GO:0040011	locomotion
0.40	GO:0006936	muscle contraction
0.36	GO:0034968	histone lysine methylation
0.36	GO:0007018	microtubule-based movement
0.35	GO:0006468	protein phosphorylation

0.37	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.36	GO:0005198	structural molecule activity
0.36	GO:0018024	histone-lysine N-methyltransferase activity
0.36	GO:0003777	microtubule motor activity
0.36	GO:0008017	microtubule binding
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0004672	protein kinase activity

0.35	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.37

GO:0003950

tr|T1G6H8|T1G6H8_HELRO
Uncharacterized protein
Search

0.59	Dual specificity protein phosphatase 10

0.80	GO:0000188	inactivation of MAPK activity
0.73	GO:0035335	peptidyl-tyrosine dephosphorylation
0.35	GO:0045208	MAPK phosphatase export from nucleus
0.34	GO:0045204	MAPK export from nucleus
0.33	GO:0016310	phosphorylation
0.33	GO:0006313	transposition, DNA-mediated
0.32	GO:0007018	microtubule-based movement
0.31	GO:0007165	signal transduction

0.81	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity
0.74	GO:0004725	protein tyrosine phosphatase activity
0.33	GO:0016301	kinase activity
0.33	GO:0004803	transposase activity
0.32	GO:0003777	microtubule motor activity
0.32	GO:0003676	nucleic acid binding

0.41	GO:0005654	nucleoplasm
0.36	GO:0005737	cytoplasm
0.33	GO:0097708	intracellular vesicle
0.32	GO:0009277	fungal-type cell wall
0.30	GO:0031224	intrinsic component of membrane

0.81

GO:0017017

tr|T1G6H9|T1G6H9_HELRO
Uncharacterized protein
Search

0.62	Ubiquinol-cytochrome c oxidoreductase

0.61	GO:0022900	electron transport chain
0.38	GO:0018095	protein polyglutamylation
0.36	GO:0006119	oxidative phosphorylation
0.36	GO:0045333	cellular respiration

0.74	GO:0016681	oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor
0.62	GO:0009055	electron transfer activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.39	GO:0005750	mitochondrial respiratory chain complex III
0.30	GO:0016021	integral component of membrane

0.74

EC:1.10.2

GO:0016681

tr|T1G6I0|T1G6I0_HELRO
Uncharacterized protein
Search

0.85	AMP-activated protein kinase beta subunit

0.56	GO:0016310	phosphorylation
0.51	GO:0035090	maintenance of apical/basal cell polarity
0.50	GO:0070050	neuron cellular homeostasis
0.34	GO:0006464	cellular protein modification process

0.58	GO:0016301	kinase activity
0.35	GO:0042802	identical protein binding
0.34	GO:0060089	molecular transducer activity
0.34	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.33	GO:0140096	catalytic activity, acting on a protein

0.36

GO:0031588

nucleotide-activated protein kinase complex

0.34

GO:0016773

tr|T1G6I1|T1G6I1_HELRO
Uncharacterized protein
Search

JPH2

0.43	Junctophilin-2

0.43	GO:0007517	muscle organ development
0.39	GO:1901076	positive regulation of engulfment of apoptotic cell
0.38	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity
0.37	GO:0060402	calcium ion transport into cytosol
0.36	GO:0051283	negative regulation of sequestering of calcium ion
0.36	GO:0040011	locomotion
0.35	GO:0070588	calcium ion transmembrane transport
0.35	GO:1901021	positive regulation of calcium ion transmembrane transporter activity
0.35	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol
0.35	GO:0035640	exploration behavior

0.45	GO:0008307	structural constituent of muscle
0.36	GO:0015278	calcium-release channel activity
0.35	GO:0010314	phosphatidylinositol-5-phosphate binding
0.35	GO:0070300	phosphatidic acid binding
0.35	GO:0001786	phosphatidylserine binding
0.35	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.35	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding
0.35	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.34	GO:0070273	phosphatidylinositol-4-phosphate binding
0.34	GO:0032266	phosphatidylinositol-3-phosphate binding

0.73	GO:0030314	junctional membrane complex
0.46	GO:0014701	junctional sarcoplasmic reticulum membrane
0.44	GO:0030018	Z disc
0.41	GO:0005654	nucleoplasm
0.37	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1G6I2|T1G6I2_HELRO
Uncharacterized protein
Search

UBE2J2

0.75	Ubiquitin-conjugating enzyme (Fragment)

0.50	GO:0030433	ubiquitin-dependent ERAD pathway
0.49	GO:1903955	positive regulation of protein targeting to mitochondrion
0.47	GO:0016567	protein ubiquitination
0.37	GO:0006986	response to unfolded protein
0.34	GO:0006486	protein glycosylation
0.34	GO:0006897	endocytosis
0.33	GO:0006457	protein folding

0.49	GO:0061631	ubiquitin conjugating enzyme activity
0.49	GO:0031625	ubiquitin protein ligase binding
0.44	GO:0061630	ubiquitin protein ligase activity
0.35	GO:0008378	galactosyltransferase activity
0.35	GO:0016874	ligase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0051082	unfolded protein binding

0.46	GO:0000151	ubiquitin ligase complex
0.42	GO:0005783	endoplasmic reticulum
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.35

GO:0008378

tr|T1G6I3|T1G6I3_HELRO
Uncharacterized protein
Search

0.75	Calcium-dependent protein kinase C

0.63	GO:0006468	protein phosphorylation
0.61	GO:0035556	intracellular signal transduction
0.51	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway
0.51	GO:0034351	negative regulation of glial cell apoptotic process
0.50	GO:0090330	regulation of platelet aggregation
0.50	GO:0002159	desmosome assembly
0.49	GO:0018210	peptidyl-threonine modification
0.49	GO:0001938	positive regulation of endothelial cell proliferation
0.49	GO:0043536	positive regulation of blood vessel endothelial cell migration
0.48	GO:0070555	response to interleukin-1

0.81	GO:0004697	protein kinase C activity
0.61	GO:0008270	zinc ion binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.52	GO:0035403	histone kinase activity (H3-T6 specific)
0.44	GO:0019899	enzyme binding
0.41	GO:0004712	protein serine/threonine/tyrosine kinase activity
0.38	GO:0009931	calcium-dependent protein serine/threonine kinase activity

0.44	GO:0005622	intracellular
0.44	GO:0005886	plasma membrane
0.42	GO:0012505	endomembrane system
0.39	GO:0043227	membrane-bounded organelle
0.37	GO:0036477	somatodendritic compartment
0.37	GO:0043005	neuron projection
0.36	GO:0044297	cell body
0.35	GO:0120038	plasma membrane bounded cell projection part
0.34	GO:0097731	9+0 non-motile cilium
0.34	GO:0014069	postsynaptic density

0.81

EC:2.7.11.13

GO:0004697

tr|T1G6I4|T1G6I4_HELRO
Uncharacterized protein
Search

0.63	GO:0043113	receptor clustering
0.62	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway
0.39	GO:0006508	proteolysis
0.38	GO:0010951	negative regulation of endopeptidase activity
0.38	GO:0090099	negative regulation of decapentaplegic signaling pathway
0.37	GO:0032927	positive regulation of activin receptor signaling pathway
0.37	GO:0032926	negative regulation of activin receptor signaling pathway
0.34	GO:0006898	receptor-mediated endocytosis
0.34	GO:0051260	protein homooligomerization
0.33	GO:0035335	peptidyl-tyrosine dephosphorylation

0.64	GO:0043236	laminin binding
0.63	GO:0005509	calcium ion binding
0.40	GO:0008233	peptidase activity
0.39	GO:0004867	serine-type endopeptidase inhibitor activity
0.35	GO:0005044	scavenger receptor activity
0.34	GO:0004064	arylesterase activity
0.33	GO:0008270	zinc ion binding
0.33	GO:0090729	toxin activity
0.33	GO:0004725	protein tyrosine phosphatase activity
0.32	GO:0017171	serine hydrolase activity

0.45	GO:0005886	plasma membrane
0.45	GO:0005578	proteinaceous extracellular matrix
0.37	GO:0044420	extracellular matrix component
0.35	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.40

GO:0008233

tr|T1G6I5|T1G6I5_HELRO
Uncharacterized protein
Search

tr|T1G6I6|T1G6I6_HELRO
Uncharacterized protein
Search

0.72	Mitochondrial ribosomal protein L11

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.38	GO:0000027	ribosomal large subunit assembly
0.32	GO:0036211	protein modification process
0.32	GO:0016310	phosphorylation

0.64	GO:0003735	structural constituent of ribosome
0.37	GO:0019843	rRNA binding
0.32	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005840	ribosome
0.48	GO:0005759	mitochondrial matrix
0.30	GO:0031224	intrinsic component of membrane

tr|T1G6I7|T1G6I7_HELRO
Uncharacterized protein
Search

0.55	Potassium channel tetramerisation domain-containing protein, putative

0.77	GO:0051260	protein homooligomerization
0.48	GO:0090327	negative regulation of locomotion involved in locomotory behavior
0.47	GO:0002121	inter-male aggressive behavior
0.46	GO:0008049	male courtship behavior
0.46	GO:0030431	sleep

0.34

GO:0004114

3',5'-cyclic-nucleotide phosphodiesterase activity

0.34

EC:3.1.4.17

GO:0004114

tr|T1G6I8|T1G6I8_HELRO
Acyl carrier protein
Search

0.37	Acyl carrier protein (Fragment)

0.70	GO:0006633	fatty acid biosynthetic process
0.36	GO:0009245	lipid A biosynthetic process
0.35	GO:0006338	chromatin remodeling
0.34	GO:0006120	mitochondrial electron transport, NADH to ubiquinone
0.33	GO:2001141	regulation of RNA biosynthetic process
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.38	GO:0000035	acyl binding
0.37	GO:0044620	ACP phosphopantetheine attachment site binding
0.36	GO:0140104	molecular carrier activity
0.36	GO:0031177	phosphopantetheine binding
0.35	GO:0042393	histone binding
0.33	GO:0046982	protein heterodimerization activity
0.33	GO:0016887	ATPase activity
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0008144	drug binding

0.35	GO:0016514	SWI/SNF complex
0.35	GO:0005829	cytosol
0.33	GO:0070469	respiratory chain
0.33	GO:0005739	mitochondrion

0.33

GO:0016887

tr|T1G6I9|T1G6I9_HELRO
Uncharacterized protein
Search

MRPS21

0.83	Mitochondrial ribosomal protein S21

0.60	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process

0.64

GO:0003735

structural constituent of ribosome

0.61	GO:0005840	ribosome
0.35	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

tr|T1G6J0|T1G6J0_HELRO
Uncharacterized protein
Search

0.43	MAP/microtubule affinity-regulating kinase 4

0.82	GO:0030010	establishment of cell polarity
0.76	GO:0000226	microtubule cytoskeleton organization
0.63	GO:0006468	protein phosphorylation
0.42	GO:0007399	nervous system development
0.37	GO:0008284	positive regulation of cell proliferation
0.36	GO:0000737	DNA catabolic process, endonucleolytic
0.33	GO:0030030	cell projection organization
0.33	GO:0051301	cell division
0.33	GO:0007049	cell cycle

0.70	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0050321	tau-protein kinase activity
0.44	GO:0043015	gamma-tubulin binding
0.42	GO:0008017	microtubule binding
0.34	GO:0003723	RNA binding
0.33	GO:0003677	DNA binding

0.45	GO:0036064	ciliary basal body
0.43	GO:0005813	centrosome
0.43	GO:0043005	neuron projection
0.37	GO:0000930	gamma-tubulin complex
0.36	GO:0005874	microtubule
0.34	GO:0005694	chromosome
0.30	GO:0031224	intrinsic component of membrane

0.70

GO:0004674

tr|T1G6J1|T1G6J1_HELRO
Uncharacterized protein
Search

0.44	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.43	GO:0016567	protein ubiquitination
0.35	GO:0010200	response to chitin
0.33	GO:0006952	defense response
0.33	GO:0016125	sterol metabolic process
0.33	GO:0015976	carbon utilization
0.33	GO:0045842	positive regulation of mitotic metaphase/anaphase transition
0.33	GO:0045132	meiotic chromosome segregation
0.33	GO:0009792	embryo development ending in birth or egg hatching
0.32	GO:0051301	cell division

0.43	GO:0061630	ubiquitin protein ligase activity
0.38	GO:0016874	ligase activity
0.36	GO:0001871	pattern binding
0.35	GO:0030246	carbohydrate binding
0.35	GO:0008270	zinc ion binding
0.33	GO:0047750	cholestenol delta-isomerase activity
0.33	GO:0097602	cullin family protein binding
0.33	GO:0004089	carbonate dehydratase activity
0.33	GO:0019904	protein domain specific binding
0.32	GO:0003700	DNA binding transcription factor activity

0.34	GO:0005680	anaphase-promoting complex
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.38

GO:0016874

tr|T1G6J2|T1G6J2_HELRO
Lissencephaly-1 homolog
Search

PAFAH1B1

0.87	Platelet-activating factor acetylhydrolase IB subunit alpha

0.81	GO:0000132	establishment of mitotic spindle orientation
0.70	GO:0007399	nervous system development
0.67	GO:0030154	cell differentiation
0.66	GO:0051301	cell division
0.56	GO:0008090	retrograde axonal transport
0.54	GO:0090176	microtubule cytoskeleton organization involved in establishment of planar polarity
0.54	GO:0047496	vesicle transport along microtubule
0.53	GO:0051081	nuclear envelope disassembly
0.53	GO:0051661	maintenance of centrosome location
0.53	GO:0042249	establishment of planar polarity of embryonic epithelium

0.79	GO:0070840	dynein complex binding
0.51	GO:0051219	phosphoprotein binding
0.48	GO:0008017	microtubule binding
0.47	GO:0042803	protein homodimerization activity
0.40	GO:0016787	hydrolase activity
0.39	GO:0045505	dynein intermediate chain binding
0.35	GO:0047179	platelet-activating factor acetyltransferase activity
0.35	GO:0034452	dynactin binding
0.35	GO:0043274	phospholipase binding
0.34	GO:0008168	methyltransferase activity

0.73	GO:0005874	microtubule
0.72	GO:0005875	microtubule associated complex
0.71	GO:0005815	microtubule organizing center
0.56	GO:0031965	nuclear membrane
0.56	GO:0005819	spindle
0.54	GO:1904115	axon cytoplasm
0.51	GO:0032420	stereocilium
0.51	GO:0000776	kinetochore
0.50	GO:0005938	cell cortex
0.49	GO:0031252	cell leading edge

0.40

GO:0016787

tr|T1G6J3|T1G6J3_HELRO
Uncharacterized protein
Search

0.47	GO:1901265	nucleoside phosphate binding
0.46	GO:0036094	small molecule binding

0.30

GO:0044425

membrane part

tr|T1G6J4|T1G6J4_HELRO
Uncharacterized protein
Search

SLMAP

0.85	Sarcolemmal membrane-associated protein (Fragment)

0.81	GO:0006936	muscle contraction
0.41	GO:1905150	regulation of voltage-gated sodium channel activity
0.41	GO:1900825	regulation of membrane depolarization during cardiac muscle cell action potential
0.39	GO:0072659	protein localization to plasma membrane

0.36	GO:0017048	Rho GTPase binding
0.34	GO:0003924	GTPase activity
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0019001	guanyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.43	GO:0005615	extracellular space
0.39	GO:0042383	sarcolemma
0.38	GO:0005815	microtubule organizing center
0.35	GO:0005790	smooth endoplasmic reticulum
0.35	GO:0031430	M band
0.35	GO:0030018	Z disc
0.33	GO:0005887	integral component of plasma membrane

tr|T1G6J5|T1G6J5_HELRO
Uncharacterized protein
Search

KCNH2

0.43	Potassium voltage-gated channel subfamily H member 2

0.74	GO:0034765	regulation of ion transmembrane transport
0.73	GO:0071805	potassium ion transmembrane transport
0.51	GO:0099625	ventricular cardiac muscle cell membrane repolarization
0.51	GO:0086091	regulation of heart rate by cardiac conduction
0.51	GO:0086013	membrane repolarization during cardiac muscle cell action potential
0.51	GO:0086005	ventricular cardiac muscle cell action potential
0.50	GO:0043267	negative regulation of potassium ion transport
0.50	GO:0086010	membrane depolarization during action potential
0.49	GO:0023014	signal transduction by protein phosphorylation
0.49	GO:0043268	positive regulation of potassium ion transport

0.78	GO:0005249	voltage-gated potassium channel activity
0.52	GO:0055131	C3HC4-type RING finger domain binding
0.50	GO:0097110	scaffold protein binding
0.50	GO:0000155	phosphorelay sensor kinase activity
0.48	GO:0099094	ligand-gated cation channel activity
0.47	GO:0031625	ubiquitin protein ligase binding
0.46	GO:0042803	protein homodimerization activity
0.37	GO:0005230	extracellular ligand-gated ion channel activity
0.36	GO:0003777	microtubule motor activity
0.36	GO:0008017	microtubule binding

0.52	GO:1902937	inward rectifier potassium channel complex
0.47	GO:0048471	perinuclear region of cytoplasm
0.46	GO:0009986	cell surface
0.35	GO:0005635	nuclear envelope

0.50

EC:2.7.3

GO:0000155

tr|T1G6J6|T1G6J6_HELRO
Uncharacterized protein
Search

0.67	GO:0050767	regulation of neurogenesis
0.63	GO:0007155	cell adhesion
0.53	GO:0007596	blood coagulation
0.48	GO:0001775	cell activation
0.48	GO:0051258	protein polymerization
0.45	GO:0007411	axon guidance
0.43	GO:0072376	protein activation cascade
0.42	GO:0007165	signal transduction
0.41	GO:0072574	hepatocyte proliferation
0.40	GO:0006959	humoral immune response

0.49	GO:0030674	protein binding, bridging
0.46	GO:0005102	receptor binding
0.40	GO:0033691	sialic acid binding
0.38	GO:0030246	carbohydrate binding
0.37	GO:0050839	cell adhesion molecule binding
0.37	GO:0004930	G-protein coupled receptor activity
0.37	GO:0051087	chaperone binding
0.35	GO:0005198	structural molecule activity
0.35	GO:0046872	metal ion binding

0.65	GO:0044421	extracellular region part
0.42	GO:0043234	protein complex
0.39	GO:0031091	platelet alpha granule
0.38	GO:0009897	external side of plasma membrane
0.37	GO:0005938	cell cortex
0.36	GO:0005783	endoplasmic reticulum
0.30	GO:0016021	integral component of membrane

tr|T1G6J7|T1G6J7_HELRO
Uncharacterized protein
Search

PGM3

0.74	Phosphoacetylglucosamine mutase

0.76	GO:0006048	UDP-N-acetylglucosamine biosynthetic process
0.60	GO:0005975	carbohydrate metabolic process
0.45	GO:0019255	glucose 1-phosphate metabolic process
0.42	GO:0048513	animal organ development
0.42	GO:0006487	protein N-linked glycosylation
0.41	GO:0007283	spermatogenesis
0.41	GO:0006493	protein O-linked glycosylation
0.41	GO:0002520	immune system development
0.39	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway
0.38	GO:0006031	chitin biosynthetic process

0.85	GO:0004610	phosphoacetylglucosamine mutase activity
0.63	GO:0000287	magnesium ion binding
0.42	GO:0004614	phosphoglucomutase activity
0.32	GO:0003677	DNA binding

0.40	GO:0005829	cytosol
0.33	GO:0005634	nucleus

0.85	EC:5.4.2.3	GO:0004610
0.85	KEGG:R08193	GO:0004610

tr|T1G6J8|T1G6J8_HELRO
Uncharacterized protein
Search

0.61	GO:0007165	signal transduction
0.39	GO:0043087	regulation of GTPase activity
0.35	GO:0051345	positive regulation of hydrolase activity
0.33	GO:0043551	regulation of phosphatidylinositol 3-kinase activity
0.32	GO:0016310	phosphorylation

0.35	GO:0005096	GTPase activator activity
0.34	GO:0046872	metal ion binding
0.34	GO:0005085	guanyl-nucleotide exchange factor activity
0.34	GO:0035014	phosphatidylinositol 3-kinase regulator activity
0.33	GO:0003676	nucleic acid binding
0.32	GO:0016740	transferase activity

0.33	GO:0005737	cytoplasm
0.33	GO:0005942	phosphatidylinositol 3-kinase complex
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016740

tr|T1G6J9|T1G6J9_HELRO
Uncharacterized protein
Search

0.10	Homeobox protein Nkx-6.2 (Fragment)

0.60	GO:0002067	glandular epithelial cell differentiation
0.57	GO:0031018	endocrine pancreas development
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0045595	regulation of cell differentiation
0.55	GO:2000026	regulation of multicellular organismal development
0.54	GO:0048699	generation of neurons
0.53	GO:0045165	cell fate commitment
0.52	GO:0061387	regulation of extent of cell growth

0.65	GO:0043565	sequence-specific DNA binding
0.46	GO:0003700	DNA binding transcription factor activity
0.42	GO:0070491	repressing transcription factor binding
0.42	GO:0001012	RNA polymerase II regulatory region DNA binding
0.41	GO:0003690	double-stranded DNA binding
0.34	GO:0003682	chromatin binding
0.33	GO:0003924	GTPase activity
0.32	GO:0005525	GTP binding

0.61	GO:0005634	nucleus
0.33	GO:0005856	cytoskeleton
0.33	GO:0070062	extracellular exosome
0.33	GO:0099512	supramolecular fiber
0.33	GO:0005829	cytosol
0.32	GO:0044446	intracellular organelle part

tr|T1G6K0|T1G6K0_HELRO
Uncharacterized protein
Search

VPS33A

0.81	Small G protein signaling modulator 1

0.80	GO:0006904	vesicle docking involved in exocytosis
0.54	GO:0030220	platelet formation
0.54	GO:0048070	regulation of developmental pigmentation
0.52	GO:0043473	pigmentation
0.38	GO:0035751	regulation of lysosomal lumen pH
0.38	GO:0097352	autophagosome maturation
0.38	GO:0032418	lysosome localization
0.38	GO:0008333	endosome to lysosome transport
0.37	GO:0051648	vesicle localization
0.35	GO:0015031	protein transport

0.34	GO:0005515	protein binding
0.34	GO:0044877	macromolecular complex binding

0.54	GO:0033263	CORVET complex
0.52	GO:0005776	autophagosome
0.50	GO:0005764	lysosome
0.39	GO:0005774	vacuolar membrane
0.38	GO:0030897	HOPS complex
0.38	GO:0071439	clathrin complex
0.37	GO:0031902	late endosome membrane
0.37	GO:0030123	AP-3 adaptor complex
0.37	GO:0005769	early endosome
0.37	GO:0030136	clathrin-coated vesicle

tr|T1G6K1|T1G6K1_HELRO
Uncharacterized protein
Search

0.74	Erythrocyte membrane protein band 4.1 3

0.75	GO:0007016	cytoskeletal anchoring at plasma membrane
0.71	GO:0001558	regulation of cell growth
0.53	GO:0030866	cortical actin cytoskeleton organization
0.38	GO:0031032	actomyosin structure organization

0.71	GO:0008092	cytoskeletal protein binding
0.57	GO:0005198	structural molecule activity
0.32	GO:0003676	nucleic acid binding

0.69	GO:0005856	cytoskeleton
0.68	GO:0005911	cell-cell junction
0.51	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1G6K2|T1G6K2_HELRO
Uncharacterized protein
Search

0.58	GO:0007219	Notch signaling pathway
0.53	GO:0007275	multicellular organism development
0.46	GO:0050793	regulation of developmental process
0.46	GO:0030154	cell differentiation
0.41	GO:0048522	positive regulation of cellular process
0.37	GO:0007155	cell adhesion
0.36	GO:0006030	chitin metabolic process
0.36	GO:0009653	anatomical structure morphogenesis
0.36	GO:0031323	regulation of cellular metabolic process
0.36	GO:0051171	regulation of nitrogen compound metabolic process

0.66	GO:0005509	calcium ion binding
0.50	GO:0005112	Notch binding
0.38	GO:0004872	receptor activity
0.36	GO:0008061	chitin binding
0.35	GO:0017147	Wnt-protein binding
0.34	GO:0008201	heparin binding
0.34	GO:0098772	molecular function regulator
0.34	GO:0005201	extracellular matrix structural constituent
0.34	GO:0004713	protein tyrosine kinase activity
0.33	GO:0005178	integrin binding

0.37	GO:0005576	extracellular region
0.34	GO:0005887	integral component of plasma membrane
0.34	GO:0030054	cell junction
0.33	GO:0099512	supramolecular fiber
0.33	GO:0009925	basal plasma membrane
0.33	GO:0097517	contractile actin filament bundle
0.33	GO:0005902	microvillus
0.33	GO:0042641	actomyosin
0.33	GO:0016324	apical plasma membrane
0.33	GO:0098857	membrane microdomain

0.34

GO:0004713

tr|T1G6K3|T1G6K3_HELRO
Uncharacterized protein
Search

0.73	Tubby like protein 4a

0.56	GO:0035493	SNARE complex assembly
0.54	GO:0035556	intracellular signal transduction
0.52	GO:0016567	protein ubiquitination
0.52	GO:0061512	protein localization to cilium
0.50	GO:0099536	synaptic signaling
0.35	GO:0006508	proteolysis
0.34	GO:0023014	signal transduction by protein phosphorylation
0.33	GO:0055085	transmembrane transport

0.48	GO:0035091	phosphatidylinositol binding
0.36	GO:0008237	metallopeptidase activity
0.36	GO:0004707	MAP kinase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0003676	nucleic acid binding

0.48	GO:0005929	cilium
0.42	GO:0005622	intracellular
0.30	GO:0031224	intrinsic component of membrane

0.36	EC:2.7.11.24	GO:0004707
0.36	KEGG:R00162	GO:0004707

tr|T1G6K4|T1G6K4_HELRO
Guanylate cyclase
Search

0.42	Guanylate cyclase

0.82	GO:0006182	cGMP biosynthetic process
0.63	GO:0006468	protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.41	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus
0.41	GO:0007168	receptor guanylyl cyclase signaling pathway
0.40	GO:1900194	negative regulation of oocyte maturation
0.39	GO:0051447	negative regulation of meiotic cell cycle
0.38	GO:0060348	bone development
0.37	GO:0022414	reproductive process
0.35	GO:0018212	peptidyl-tyrosine modification

0.82	GO:0004383	guanylate cyclase activity
0.63	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0016941	natriuretic peptide receptor activity
0.40	GO:0004016	adenylate cyclase activity
0.40	GO:0017046	peptide hormone binding
0.37	GO:0042802	identical protein binding

0.45	GO:0005622	intracellular
0.38	GO:0005887	integral component of plasma membrane
0.36	GO:0043234	protein complex
0.35	GO:0044297	cell body
0.35	GO:0043005	neuron projection
0.33	GO:0097730	non-motile cilium
0.33	GO:0036477	somatodendritic compartment
0.33	GO:0120038	plasma membrane bounded cell projection part

0.82

GO:0004383

tr|T1G6K5|T1G6K5_HELRO
Uncharacterized protein
Search

0.48	Potassium voltage-gated channel subfamily H member 7

0.74	GO:0034765	regulation of ion transmembrane transport
0.70	GO:0071805	potassium ion transmembrane transport
0.54	GO:0086091	regulation of heart rate by cardiac conduction
0.51	GO:0099625	ventricular cardiac muscle cell membrane repolarization
0.50	GO:0086013	membrane repolarization during cardiac muscle cell action potential
0.50	GO:0086005	ventricular cardiac muscle cell action potential
0.50	GO:0023014	signal transduction by protein phosphorylation
0.50	GO:0043267	negative regulation of potassium ion transport
0.49	GO:0086010	membrane depolarization during action potential
0.49	GO:0043268	positive regulation of potassium ion transport

0.75	GO:0005249	voltage-gated potassium channel activity
0.51	GO:0055131	C3HC4-type RING finger domain binding
0.50	GO:0000155	phosphorelay sensor kinase activity
0.49	GO:0097110	scaffold protein binding
0.48	GO:0099094	ligand-gated cation channel activity
0.47	GO:0031625	ubiquitin protein ligase binding
0.45	GO:0042803	protein homodimerization activity

0.51	GO:1902937	inward rectifier potassium channel complex
0.47	GO:0048471	perinuclear region of cytoplasm
0.45	GO:0009986	cell surface
0.36	GO:0005635	nuclear envelope

0.50

EC:2.7.3

GO:0000155

tr|T1G6K6|T1G6K6_HELRO
Uncharacterized protein
Search

COX15

0.84	Cytochrome c oxidase assembly protein COX15

0.81	GO:0046160	heme a metabolic process
0.72	GO:0006783	heme biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.41	GO:0008535	respiratory chain complex IV assembly
0.37	GO:1902600	hydrogen ion transmembrane transport
0.37	GO:0006091	generation of precursor metabolites and energy
0.34	GO:0007017	microtubule-based process
0.34	GO:0007010	cytoskeleton organization
0.34	GO:0055070	copper ion homeostasis

0.68	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors
0.38	GO:0015002	heme-copper terminal oxidase activity
0.38	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.37	GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor
0.37	GO:0015078	hydrogen ion transmembrane transporter activity
0.37	GO:0009055	electron transfer activity
0.35	GO:0005200	structural constituent of cytoskeleton
0.34	GO:0003924	GTPase activity
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0019001	guanyl nucleotide binding

0.42	GO:0005886	plasma membrane
0.40	GO:0031966	mitochondrial membrane
0.40	GO:0019866	organelle inner membrane
0.39	GO:0070069	cytochrome complex
0.37	GO:0005634	nucleus
0.34	GO:0005874	microtubule
0.30	GO:0016021	integral component of membrane

0.68

EC:1.3

GO:0016627

tr|T1G6K7|T1G6K7_HELRO
Uncharacterized protein
Search

NSUN6

0.88	Methyltransferase NSUN6

0.63	GO:0032259	methylation
0.49	GO:0006364	rRNA processing
0.45	GO:0009451	RNA modification
0.41	GO:1903506	regulation of nucleic acid-templated transcription
0.41	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.41	GO:0010468	regulation of gene expression
0.38	GO:0044260	cellular macromolecule metabolic process
0.37	GO:0008033	tRNA processing

0.63	GO:0008168	methyltransferase activity
0.59	GO:0003723	RNA binding
0.45	GO:0140102	catalytic activity, acting on a rRNA
0.37	GO:0140101	catalytic activity, acting on a tRNA

0.39	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.63

GO:0008168

tr|T1G6K8|T1G6K8_HELRO
Uncharacterized protein
Search

DPY19L3

0.97	LOW QUALITY PROTEIN: probable C-mannosyltransferase DPY19L3

0.41	GO:0018317	protein C-linked glycosylation via tryptophan
0.40	GO:0035268	protein mannosylation

0.65

GO:0016757

transferase activity, transferring glycosyl groups

0.39	GO:0005637	nuclear inner membrane
0.30	GO:0044425	membrane part

0.65

GO:0016757

tr|T1G6K9|T1G6K9_HELRO
Uncharacterized protein
Search

0.64	GO:0006915	apoptotic process
0.61	GO:0006508	proteolysis
0.55	GO:0042981	regulation of apoptotic process
0.45	GO:0046672	positive regulation of compound eye retinal cell programmed cell death
0.44	GO:0035070	salivary gland histolysis
0.44	GO:2001056	positive regulation of cysteine-type endopeptidase activity
0.44	GO:0010165	response to X-ray
0.44	GO:0016322	neuron remodeling
0.44	GO:0010623	programmed cell death involved in cell development
0.43	GO:0032933	SREBP signaling pathway

0.75	GO:0004197	cysteine-type endopeptidase activity
0.46	GO:1990525	BIR domain binding
0.36	GO:0004871	signal transducer activity
0.36	GO:0035877	death effector domain binding
0.35	GO:0097110	scaffold protein binding
0.34	GO:0031625	ubiquitin protein ligase binding
0.34	GO:0003924	GTPase activity
0.34	GO:0005525	GTP binding
0.34	GO:0042802	identical protein binding
0.34	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process

0.38	GO:0005737	cytoplasm
0.36	GO:0031265	CD95 death-inducing signaling complex
0.34	GO:0005654	nucleoplasm
0.33	GO:1902494	catalytic complex
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.75	EC:3.4.22	GO:0004197
0.34	KEGG:R00497	GO:0004363

tr|T1G6L0|T1G6L0_HELRO
Uncharacterized protein
Search

0.24	Tyrosine-protein kinase

0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.43	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.41	GO:0046777	protein autophosphorylation
0.40	GO:0042127	regulation of cell proliferation
0.40	GO:0045087	innate immune response
0.40	GO:0030154	cell differentiation
0.39	GO:0035924	cellular response to vascular endothelial growth factor stimulus
0.39	GO:0043304	regulation of mast cell degranulation
0.38	GO:2000251	positive regulation of actin cytoskeleton reorganization
0.38	GO:0016477	cell migration

0.77	GO:0004713	protein tyrosine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0019199	transmembrane receptor protein kinase activity
0.39	GO:0005102	receptor binding
0.38	GO:0019838	growth factor binding
0.37	GO:0035091	phosphatidylinositol binding
0.36	GO:0008017	microtubule binding

0.41	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.39	GO:0005856	cytoskeleton
0.38	GO:0005912	adherens junction
0.37	GO:0030055	cell-substrate junction
0.36	GO:0031410	cytoplasmic vesicle
0.34	GO:0019028	viral capsid
0.33	GO:0005911	cell-cell junction
0.33	GO:0005829	cytosol
0.33	GO:0005887	integral component of plasma membrane

0.77

GO:0004713

tr|T1G6L1|T1G6L1_HELRO
Uncharacterized protein
Search

0.61	Regulator of G-protein signaling

0.81	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.62	GO:0035556	intracellular signal transduction
0.40	GO:0043547	positive regulation of GTPase activity
0.38	GO:0042407	cristae formation
0.33	GO:0009968	negative regulation of signal transduction
0.33	GO:0046854	phosphatidylinositol phosphorylation

0.63	GO:0004871	signal transducer activity
0.40	GO:0005096	GTPase activator activity
0.34	GO:0031681	G-protein beta-subunit binding

0.80	GO:1905360	GTPase complex
0.78	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.65	GO:0098797	plasma membrane protein complex
0.37	GO:0061617	MICOS complex
0.33	GO:0005829	cytosol

tr|T1G6L2|T1G6L2_HELRO
Glutathione S-transferase kappa
Search

GSTK1

0.70	Glutathione S-transferase kappa

0.53	GO:0055114	oxidation-reduction process
0.45	GO:0030855	epithelial cell differentiation
0.44	GO:0006749	glutathione metabolic process
0.43	GO:0098869	cellular oxidant detoxification
0.36	GO:1901685	glutathione derivative metabolic process
0.33	GO:0044272	sulfur compound biosynthetic process
0.33	GO:0006468	protein phosphorylation
0.32	GO:1901566	organonitrogen compound biosynthetic process

0.72	GO:0015035	protein disulfide oxidoreductase activity
0.72	GO:0004364	glutathione transferase activity
0.46	GO:0004602	glutathione peroxidase activity
0.43	GO:0005102	receptor binding
0.33	GO:0004672	protein kinase activity
0.33	GO:0018845	2-hydroxychromene-2-carboxylate isomerase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.45	GO:0005777	peroxisome
0.40	GO:0031966	mitochondrial membrane
0.40	GO:0019866	organelle inner membrane
0.36	GO:0070062	extracellular exosome
0.35	GO:0005759	mitochondrial matrix
0.30	GO:0016021	integral component of membrane

0.72	EC:2.5.1.18	GO:0004364
0.33	KEGG:R05137	GO:0018845

tr|T1G6L3|T1G6L3_HELRO
Sodium channel protein
Search

SCN4AB

0.45	Putative sodium channel protein type 4 subunit alpha B

0.76	GO:0035725	sodium ion transmembrane transport
0.76	GO:0034765	regulation of ion transmembrane transport
0.47	GO:0050877	nervous system process
0.46	GO:0086010	membrane depolarization during action potential
0.45	GO:0051930	regulation of sensory perception of pain
0.45	GO:0035637	multicellular organismal signaling
0.39	GO:0007154	cell communication
0.35	GO:0046684	response to pyrethroid
0.35	GO:0071236	cellular response to antibiotic
0.34	GO:0048266	behavioral response to pain

0.84	GO:0005248	voltage-gated sodium channel activity
0.73	GO:0022832	voltage-gated channel activity
0.71	GO:0022839	ion gated channel activity
0.70	GO:0008381	mechanosensitive ion channel activity
0.46	GO:0005509	calcium ion binding
0.38	GO:0008081	phosphoric diester hydrolase activity
0.34	GO:0031402	sodium ion binding
0.34	GO:0005516	calmodulin binding
0.32	GO:0005267	potassium channel activity

0.83	GO:0001518	voltage-gated sodium channel complex
0.47	GO:0044299	C-fiber
0.34	GO:0043025	neuronal cell body
0.34	GO:0005737	cytoplasm
0.34	GO:0070062	extracellular exosome
0.32	GO:0008076	voltage-gated potassium channel complex

0.38

EC:3.1.4

GO:0008081

tr|T1G6L4|T1G6L4_HELRO
Uncharacterized protein
Search

0.40	Voltage-sensitive sodium channel (Fragment)

0.75	GO:0035725	sodium ion transmembrane transport
0.73	GO:0034765	regulation of ion transmembrane transport
0.43	GO:0019233	sensory perception of pain
0.38	GO:0019228	neuronal action potential
0.38	GO:0086010	membrane depolarization during action potential
0.33	GO:0071805	potassium ion transmembrane transport

0.83	GO:0005248	voltage-gated sodium channel activity
0.71	GO:0022832	voltage-gated channel activity
0.69	GO:0022839	ion gated channel activity
0.68	GO:0008381	mechanosensitive ion channel activity
0.63	GO:0005509	calcium ion binding
0.41	GO:0008081	phosphoric diester hydrolase activity
0.34	GO:0005267	potassium channel activity

0.82	GO:0001518	voltage-gated sodium channel complex
0.34	GO:0008076	voltage-gated potassium channel complex

0.41

EC:3.1.4

GO:0008081

tr|T1G6L5|T1G6L5_HELRO
Uncharacterized protein
Search

TBC1D25

0.96	Ornithine aminotransferase-like 1 (Predicted)

0.76	GO:1901096	regulation of autophagosome maturation
0.70	GO:0043547	positive regulation of GTPase activity
0.62	GO:0031338	regulation of vesicle fusion
0.53	GO:0006886	intracellular protein transport
0.42	GO:0007298	border follicle cell migration
0.42	GO:0008340	determination of adult lifespan
0.41	GO:0006914	autophagy
0.41	GO:0016125	sterol metabolic process
0.36	GO:0006468	protein phosphorylation

0.70	GO:0005096	GTPase activator activity
0.60	GO:0017137	Rab GTPase binding
0.45	GO:0008483	transaminase activity
0.42	GO:0047750	cholestenol delta-isomerase activity
0.38	GO:0008146	sulfotransferase activity
0.36	GO:0004672	protein kinase activity
0.34	GO:0003723	RNA binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.76	GO:0005776	autophagosome
0.52	GO:0012505	endomembrane system
0.40	GO:0031410	cytoplasmic vesicle
0.30	GO:0016020	membrane

0.45

EC:2.6.1

GO:0008483

tr|T1G6L6|T1G6L6_HELRO
Metalloendopeptidase
Search

0.29	Metalloendopeptidase

0.68	GO:0018996	molting cycle, collagen and cuticulin-based cuticle
0.61	GO:0006508	proteolysis
0.37	GO:0006032	chitin catabolic process
0.36	GO:0016998	cell wall macromolecule catabolic process

0.70	GO:0004222	metalloendopeptidase activity
0.60	GO:0008270	zinc ion binding
0.37	GO:0004568	chitinase activity

0.37	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.70

GO:0004222

tr|T1G6L7|T1G6L7_HELRO
Uncharacterized protein
Search

tr|T1G6L8|T1G6L8_HELRO
Uncharacterized protein
Search

0.62	GO:0071897	DNA biosynthetic process
0.61	GO:0006260	DNA replication
0.44	GO:1904799	regulation of neuron remodeling
0.44	GO:0007430	terminal branching, open tracheal system
0.44	GO:0035071	salivary gland cell autophagic cell death
0.43	GO:0048675	axon extension
0.43	GO:0016246	RNA interference
0.42	GO:0050768	negative regulation of neurogenesis
0.40	GO:0000077	DNA damage checkpoint
0.40	GO:1904668	positive regulation of ubiquitin protein ligase activity

0.65	GO:0003887	DNA-directed DNA polymerase activity
0.51	GO:0003677	DNA binding
0.42	GO:0004398	histidine decarboxylase activity
0.40	GO:0097027	ubiquitin-protein transferase activator activity
0.40	GO:0010997	anaphase-promoting complex binding
0.35	GO:0022857	transmembrane transporter activity
0.35	GO:0008270	zinc ion binding

0.42	GO:0030425	dendrite
0.41	GO:0030424	axon
0.41	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.65

EC:2.7.7.7

GO:0003887

tr|T1G6L9|T1G6L9_HELRO
Uncharacterized protein
Search

tr|T1G6M0|T1G6M0_HELRO
Uncharacterized protein
Search

AP3M1

0.86	AP-3 complex subunit mu

0.69	GO:0006886	intracellular protein transport
0.69	GO:0016192	vesicle-mediated transport
0.55	GO:0008089	anterograde axonal transport
0.54	GO:0047496	vesicle transport along microtubule
0.53	GO:0097480	establishment of synaptic vesicle localization
0.42	GO:0033060	ocellus pigmentation
0.42	GO:0007220	Notch receptor processing
0.41	GO:0006726	eye pigment biosynthetic process
0.41	GO:0008340	determination of adult lifespan
0.38	GO:0044550	secondary metabolite biosynthetic process

0.52

GO:0017137

Rab GTPase binding

0.79	GO:0030131	clathrin adaptor complex
0.55	GO:1904115	axon cytoplasm
0.39	GO:0030659	cytoplasmic vesicle membrane
0.38	GO:0005794	Golgi apparatus
0.37	GO:0005765	lysosomal membrane
0.34	GO:0030136	clathrin-coated vesicle

tr|T1G6M1|T1G6M1_HELRO
Uncharacterized protein
Search

0.41	Atypical/RIO/RIO2 protein kinase

0.63	GO:0006468	protein phosphorylation
0.53	GO:2000199	positive regulation of ribonucleoprotein complex localization
0.53	GO:2000206	regulation of ribosomal small subunit export from nucleus
0.52	GO:0032241	positive regulation of nucleobase-containing compound transport
0.51	GO:2000234	positive regulation of rRNA processing
0.49	GO:0090316	positive regulation of intracellular protein transport
0.48	GO:0030490	maturation of SSU-rRNA
0.48	GO:0030071	regulation of mitotic metaphase/anaphase transition
0.38	GO:0046828	regulation of RNA import into nucleus
0.32	GO:0006508	proteolysis

0.70	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0004252	serine-type endopeptidase activity
0.33	GO:0005515	protein binding
0.32	GO:0046872	metal ion binding

0.49	GO:0030688	preribosome, small subunit precursor
0.37	GO:0005737	cytoplasm
0.36	GO:0035770	ribonucleoprotein granule
0.34	GO:0005634	nucleus
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.70

GO:0004674

tr|T1G6M2|T1G6M2_HELRO
Uncharacterized protein
Search

0.64	AN1-type zinc finger protein 3 (Fragment)

0.43

GO:0031018

endocrine pancreas development

0.63	GO:0008270	zinc ion binding
0.46	GO:0003677	DNA binding

tr|T1G6M3|T1G6M3_HELRO
Uncharacterized protein
Search

0.10	Zinc finger protein ZIC 5 (Fragment)

0.53	GO:0007417	central nervous system development
0.52	GO:0061351	neural precursor cell proliferation
0.51	GO:0048513	animal organ development
0.51	GO:0060322	head development
0.45	GO:0048598	embryonic morphogenesis
0.45	GO:0072175	epithelial tube formation
0.45	GO:0021915	neural tube development
0.44	GO:0060070	canonical Wnt signaling pathway
0.42	GO:0030154	cell differentiation
0.42	GO:0051960	regulation of nervous system development

0.50	GO:0003676	nucleic acid binding
0.34	GO:0003700	DNA binding transcription factor activity
0.34	GO:0046872	metal ion binding

0.36

GO:0005634

nucleus

tr|T1G6M4|T1G6M4_HELRO
Uncharacterized protein
Search

0.76	GO:0035725	sodium ion transmembrane transport
0.74	GO:0034765	regulation of ion transmembrane transport
0.54	GO:0019233	sensory perception of pain
0.45	GO:0086043	bundle of His cell action potential
0.44	GO:0086016	AV node cell action potential
0.44	GO:0060371	regulation of atrial cardiac muscle cell membrane depolarization
0.43	GO:0055117	regulation of cardiac muscle contraction
0.43	GO:0002027	regulation of heart rate
0.39	GO:0019228	neuronal action potential
0.39	GO:0086010	membrane depolarization during action potential

0.83	GO:0005248	voltage-gated sodium channel activity
0.71	GO:0022832	voltage-gated channel activity
0.69	GO:0022839	ion gated channel activity
0.69	GO:0008381	mechanosensitive ion channel activity
0.63	GO:0005509	calcium ion binding
0.43	GO:0044325	ion channel binding
0.33	GO:0032550	purine ribonucleoside binding
0.32	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.82	GO:0001518	voltage-gated sodium channel complex
0.36	GO:0071439	clathrin complex
0.36	GO:0044299	C-fiber
0.35	GO:0070062	extracellular exosome

tr|T1G6M5|T1G6M5_HELRO
Uncharacterized protein
Search

0.50	SRm160/300 splicing coactivator (Fragment)

0.70

GO:0006397

mRNA processing

tr|T1G6M6|T1G6M6_HELRO
Uncharacterized protein
Search

0.11	High mobility group 1 protein (Fragment)

0.52	GO:0006260	DNA replication
0.51	GO:0006281	DNA repair
0.48	GO:0090139	mitochondrial DNA packaging
0.47	GO:0006351	transcription, DNA-templated
0.46	GO:1903506	regulation of nucleic acid-templated transcription
0.46	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.46	GO:0010468	regulation of gene expression
0.44	GO:0000001	mitochondrion inheritance
0.43	GO:0000002	mitochondrial genome maintenance
0.36	GO:0043043	peptide biosynthetic process

0.55	GO:0003677	DNA binding
0.37	GO:0003735	structural constituent of ribosome
0.33	GO:0016491	oxidoreductase activity

0.61	GO:0005634	nucleus
0.55	GO:0005694	chromosome
0.44	GO:0042645	mitochondrial nucleoid
0.36	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.33

GO:0016491

tr|T1G6M7|T1G6M7_HELRO
Uncharacterized protein
Search

0.42	Oxysterol-binding protein 1

0.73	GO:0006869	lipid transport
0.38	GO:0044128	positive regulation of growth of symbiont in host
0.36	GO:0015850	organic hydroxy compound transport
0.36	GO:0007291	sperm individualization
0.35	GO:0007030	Golgi organization
0.34	GO:0006886	intracellular protein transport
0.33	GO:0045892	negative regulation of transcription, DNA-templated

0.37	GO:0015248	sterol transporter activity
0.37	GO:0070273	phosphatidylinositol-4-phosphate binding
0.36	GO:0019904	protein domain specific binding

0.36	GO:0005794	Golgi apparatus
0.36	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0030054	cell junction
0.35	GO:0005730	nucleolus
0.35	GO:0098588	bounding membrane of organelle
0.35	GO:0005654	nucleoplasm
0.35	GO:0005829	cytosol
0.35	GO:0031984	organelle subcompartment
0.34	GO:0005783	endoplasmic reticulum
0.30	GO:0016021	integral component of membrane

tr|T1G6M8|T1G6M8_HELRO
Uncharacterized protein
Search

0.61	GO:0032781	positive regulation of ATPase activity
0.50	GO:0006950	response to stress

0.62	GO:0001671	ATPase activator activity
0.59	GO:0051087	chaperone binding
0.55	GO:0008375	acetylglucosaminyltransferase activity

0.30

GO:0016020

membrane

0.55

GO:0008375

tr|T1G6M9|T1G6M9_HELRO
Uncharacterized protein
Search

OSTC

0.64	Oligosaccharyltransferase complex non-catalytic subunit

0.38	GO:0043413	macromolecule glycosylation
0.38	GO:0009101	glycoprotein biosynthetic process
0.35	GO:0006464	cellular protein modification process

0.45	GO:0016740	transferase activity
0.33	GO:0005515	protein binding

0.49	GO:0008250	oligosaccharyltransferase complex
0.30	GO:0031224	intrinsic component of membrane

0.45

GO:0016740

tr|T1G6N0|T1G6N0_HELRO
Uncharacterized protein
Search

0.76	Putative membrane protein associated with esophageal cancer in s (Fragment)

0.79	GO:0042147	retrograde transport, endosome to Golgi
0.64	GO:0015031	protein transport

0.35

GO:0005509

calcium ion binding

0.83	GO:0030906	retromer, cargo-selective complex
0.67	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|T1G6N1|T1G6N1_HELRO
Uncharacterized protein
Search

TAZ

0.46	Tafazzin exon 5 deleted variant short form

0.67	GO:0006644	phospholipid metabolic process
0.53	GO:0007007	inner mitochondrial membrane organization
0.51	GO:0007507	heart development
0.50	GO:0060048	cardiac muscle contraction
0.49	GO:0032981	mitochondrial respiratory chain complex I assembly
0.49	GO:0007519	skeletal muscle tissue development
0.48	GO:0046486	glycerolipid metabolic process
0.47	GO:0030097	hemopoiesis
0.45	GO:0042775	mitochondrial ATP synthesis coupled electron transport
0.42	GO:0008610	lipid biosynthetic process

0.63	GO:0016746	transferase activity, transferring acyl groups
0.34	GO:0004842	ubiquitin-protein transferase activity
0.32	GO:0003723	RNA binding
0.32	GO:0005548	phospholipid transporter activity
0.32	GO:0061659	ubiquitin-like protein ligase activity
0.32	GO:0004252	serine-type endopeptidase activity
0.32	GO:0009982	pseudouridine synthase activity

0.44	GO:0005829	cytosol
0.43	GO:0005739	mitochondrion
0.41	GO:0005634	nucleus
0.40	GO:0031967	organelle envelope
0.40	GO:0031090	organelle membrane
0.32	GO:1990745	EARP complex
0.32	GO:0000938	GARP complex
0.30	GO:0016021	integral component of membrane

0.63	EC:2.3	GO:0016746
0.34	KEGG:R03876	GO:0004842

tr|T1G6N2|T1G6N2_HELRO
Uncharacterized protein
Search

0.16	Whn transcription factor (Fragment)

0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity

0.61

GO:0005634

nucleus

tr|T1G6N3|T1G6N3_HELRO
Metalloendopeptidase
Search

0.62	Metalloendopeptidase

0.61	GO:0006508	proteolysis
0.50	GO:0048264	determination of ventral identity
0.49	GO:0048736	appendage development
0.45	GO:0048729	tissue morphogenesis
0.44	GO:0060429	epithelium development
0.44	GO:0036342	post-anal tail morphogenesis
0.44	GO:0030513	positive regulation of BMP signaling pathway
0.44	GO:0035162	embryonic hemopoiesis
0.44	GO:0048468	cell development
0.43	GO:0001704	formation of primary germ layer

0.70	GO:0004222	metalloendopeptidase activity
0.70	GO:0005509	calcium ion binding
0.63	GO:0008270	zinc ion binding
0.37	GO:0005515	protein binding
0.32	GO:0008061	chitin binding

0.36	GO:0005576	extracellular region
0.31	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.70

GO:0004222

tr|T1G6N4|T1G6N4_HELRO
Uncharacterized protein
Search

tr|T1G6N5|T1G6N5_HELRO
Uncharacterized protein
Search

tr|T1G6N6|T1G6N6_HELRO
Uncharacterized protein
Search

0.61	GO:0016573	histone acetylation
0.42	GO:0045944	positive regulation of transcription by RNA polymerase II
0.41	GO:2000219	positive regulation of invasive growth in response to glucose limitation
0.40	GO:0061188	negative regulation of chromatin silencing at rDNA
0.40	GO:0061186	negative regulation of chromatin silencing at silent mating-type cassette
0.40	GO:0016479	negative regulation of transcription by RNA polymerase I
0.40	GO:0031939	negative regulation of chromatin silencing at telomere
0.40	GO:0051716	cellular response to stimulus
0.39	GO:0006366	transcription by RNA polymerase II
0.39	GO:0007049	cell cycle

0.62	GO:0004402	histone acetyltransferase activity
0.44	GO:0005515	protein binding
0.40	GO:0016500	protein-hormone receptor activity
0.40	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.40	GO:0140096	catalytic activity, acting on a protein
0.40	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.39	GO:0003682	chromatin binding
0.39	GO:0004075	biotin carboxylase activity
0.38	GO:0003712	transcription cofactor activity
0.38	GO:0019213	deacetylase activity

0.43	GO:0005634	nucleus
0.43	GO:0005694	chromosome
0.43	GO:0030496	midbody
0.42	GO:0005667	transcription factor complex
0.40	GO:0005874	microtubule
0.40	GO:0106068	SUMO ligase complex
0.37	GO:0043233	organelle lumen
0.36	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.62

GO:0004402

tr|T1G6N7|T1G6N7_HELRO
Uncharacterized protein
Search

0.10	Cyclin-T2 isoform A

0.56	GO:0006351	transcription, DNA-templated
0.54	GO:1900364	negative regulation of mRNA polyadenylation
0.50	GO:0045944	positive regulation of transcription by RNA polymerase II
0.47	GO:1901409	positive regulation of phosphorylation of RNA polymerase II C-terminal domain
0.46	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity
0.43	GO:0006468	protein phosphorylation
0.38	GO:0019085	early viral transcription
0.38	GO:0019086	late viral transcription
0.37	GO:0007519	skeletal muscle tissue development
0.37	GO:0051301	cell division

0.56	GO:0097322	7SK snRNA binding
0.54	GO:0019901	protein kinase binding
0.50	GO:0070063	RNA polymerase binding
0.49	GO:0003682	chromatin binding
0.48	GO:0008134	transcription factor binding
0.48	GO:0044212	transcription regulatory region DNA binding
0.45	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity
0.34	GO:0016301	kinase activity
0.33	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.33	GO:0140096	catalytic activity, acting on a protein

0.54	GO:0008024	cyclin/CDK positive transcription elongation factor complex
0.36	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0005730	nucleolus
0.35	GO:0005829	cytosol
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.45

GO:0016538

tr|T1G6N8|T1G6N8_HELRO
Uncharacterized protein
Search

0.50	Cysteine proteinase

0.76	GO:0016579	protein deubiquitination
0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.43	GO:1902459	positive regulation of stem cell population maintenance
0.43	GO:1900425	negative regulation of defense response to bacterium
0.43	GO:0030718	germ-line stem cell population maintenance
0.42	GO:0035019	somatic stem cell population maintenance
0.42	GO:0031937	positive regulation of chromatin silencing
0.40	GO:0016570	histone modification
0.39	GO:0042981	regulation of apoptotic process
0.39	GO:0045824	negative regulation of innate immune response

0.77	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.33	GO:0050567	glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
0.32	GO:0005515	protein binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0016740	transferase activity

0.42	GO:0005730	nucleolus
0.38	GO:0016607	nuclear speck
0.34	GO:0030956	glutamyl-tRNA(Gln) amidotransferase complex
0.32	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.77

GO:0036459

tr|T1G6N9|T1G6N9_HELRO
Uncharacterized protein
Search

DENND6A

0.97	DENN domain containing 6A

0.66	GO:0065009	regulation of molecular function
0.55	GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin

0.85	GO:0017112	Rab guanyl-nucleotide exchange factor activity
0.37	GO:0030554	adenyl nucleotide binding
0.37	GO:0097367	carbohydrate derivative binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding

0.53	GO:0055037	recycling endosome
0.40	GO:0043231	intracellular membrane-bounded organelle
0.33	GO:0005829	cytosol
0.30	GO:0044425	membrane part

tr|T1G6P0|T1G6P0_HELRO
Uncharacterized protein
Search

0.47	RNA exonuclease 4

0.68	GO:0006364	rRNA processing
0.64	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.43	GO:0000027	ribosomal large subunit assembly

0.72	GO:0008408	3'-5' exonuclease activity
0.51	GO:0003676	nucleic acid binding

0.42	GO:0016607	nuclear speck
0.40	GO:0005730	nucleolus
0.33	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

tr|T1G6P1|T1G6P1_HELRO
Uncharacterized protein
Search

FBXL16

0.86	F-box and leucine-rich repeat protein 16

0.64	GO:0016567	protein ubiquitination
0.59	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
0.48	GO:0043687	post-translational protein modification

0.65

GO:0004842

ubiquitin-protein transferase activity

0.58	GO:0019005	SCF ubiquitin ligase complex
0.45	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.65

KEGG:R03876

GO:0004842

tr|T1G6P2|T1G6P2_HELRO
Uncharacterized protein
Search

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.52	GO:0007420	brain development
0.51	GO:0030182	neuron differentiation
0.48	GO:0003002	regionalization
0.48	GO:0061351	neural precursor cell proliferation
0.47	GO:0072001	renal system development
0.46	GO:0009790	embryo development
0.46	GO:0090596	sensory organ morphogenesis

0.64	GO:0043565	sequence-specific DNA binding
0.42	GO:0005351	sugar:proton symporter activity
0.39	GO:0035326	enhancer binding
0.39	GO:0001012	RNA polymerase II regulatory region DNA binding
0.38	GO:0003690	double-stranded DNA binding
0.37	GO:0003700	DNA binding transcription factor activity
0.34	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding
0.34	GO:0031490	chromatin DNA binding
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.41	GO:0000139	Golgi membrane
0.30	GO:0016021	integral component of membrane

tr|T1G6P3|T1G6P3_HELRO
Presenilin
Search

0.76	Presenilin

0.80	GO:0007219	Notch signaling pathway
0.75	GO:0016485	protein processing
0.54	GO:0042987	amyloid precursor protein catabolic process
0.43	GO:0050435	amyloid-beta metabolic process
0.43	GO:0007220	Notch receptor processing
0.42	GO:0006509	membrane protein ectodomain proteolysis
0.41	GO:0035556	intracellular signal transduction
0.40	GO:0043066	negative regulation of apoptotic process
0.40	GO:0061053	somite development
0.39	GO:0006816	calcium ion transport

0.70	GO:0004190	aspartic-type endopeptidase activity
0.37	GO:0008013	beta-catenin binding
0.37	GO:0045296	cadherin binding
0.34	GO:0030165	PDZ domain binding
0.34	GO:0005262	calcium channel activity
0.33	GO:0042803	protein homodimerization activity

0.73	GO:0000139	Golgi membrane
0.70	GO:0005789	endoplasmic reticulum membrane
0.42	GO:0035253	ciliary rootlet
0.42	GO:0043198	dendritic shaft
0.41	GO:0030426	growth cone
0.40	GO:0031594	neuromuscular junction
0.40	GO:0043025	neuronal cell body
0.40	GO:0030018	Z disc
0.40	GO:0098857	membrane microdomain
0.40	GO:0030424	axon

0.70

EC:3.4.23

GO:0004190

tr|T1G6P4|T1G6P4_HELRO
Uncharacterized protein
Search

tr|T1G6P5|T1G6P5_HELRO
Uncharacterized protein
Search

tr|T1G6P6|T1G6P6_HELRO
Uncharacterized protein
Search

0.54	52 kDa repressor of the inhibitor of the protein kinase

0.56

GO:0016310

phosphorylation

0.68	GO:0046983	protein dimerization activity
0.59	GO:0016301	kinase activity

tr|T1G6P7|T1G6P7_HELRO
Uncharacterized protein
Search

0.60	GO:0006508	proteolysis
0.53	GO:0007229	integrin-mediated signaling pathway
0.38	GO:2000415	positive regulation of fibronectin-dependent thymocyte migration
0.37	GO:2000309	positive regulation of tumor necrosis factor (ligand) superfamily member 11 production
0.37	GO:2000418	positive regulation of eosinophil migration
0.37	GO:0070245	positive regulation of thymocyte apoptotic process
0.37	GO:2000391	positive regulation of neutrophil extravasation
0.37	GO:0033089	positive regulation of T cell differentiation in thymus
0.37	GO:0002523	leukocyte migration involved in inflammatory response
0.37	GO:0045780	positive regulation of bone resorption

0.70	GO:0004222	metalloendopeptidase activity
0.53	GO:0046872	metal ion binding
0.40	GO:0002020	protease binding
0.36	GO:0017124	SH3 domain binding
0.36	GO:0050839	cell adhesion molecule binding
0.35	GO:0042802	identical protein binding

0.37	GO:1990913	sperm head plasma membrane
0.37	GO:0032127	dense core granule membrane
0.37	GO:0071133	alpha9-beta1 integrin-ADAM8 complex
0.37	GO:0009986	cell surface
0.37	GO:0071065	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex
0.37	GO:0032010	phagolysosome
0.37	GO:0070820	tertiary granule
0.37	GO:0042581	specific granule
0.37	GO:0002102	podosome
0.35	GO:0098552	side of membrane

0.70

GO:0004222

tr|T1G6P8|T1G6P8_HELRO
Uncharacterized protein
Search

0.50	short-chain dehydrogenase/reductase family 16C member 6

0.50	GO:0055114	oxidation-reduction process
0.41	GO:0006633	fatty acid biosynthetic process
0.31	GO:0055085	transmembrane transport

0.51	GO:0016491	oxidoreductase activity
0.46	GO:0004312	fatty acid synthase activity
0.41	GO:0051287	NAD binding

0.30

GO:0044425

membrane part

0.51

GO:0016491

tr|T1G6P9|T1G6P9_HELRO
Uncharacterized protein
Search

DTYMK

0.41	Deoxythymidylate kinase

0.79	GO:0006233	dTDP biosynthetic process
0.69	GO:0046939	nucleotide phosphorylation
0.46	GO:0006227	dUDP biosynthetic process
0.45	GO:0006235	dTTP biosynthetic process
0.32	GO:0005975	carbohydrate metabolic process
0.32	GO:0055114	oxidation-reduction process

0.79	GO:0004798	thymidylate kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0009041	uridylate kinase activity
0.39	GO:0004550	nucleoside diphosphate kinase activity
0.34	GO:0003756	protein disulfide isomerase activity
0.33	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
0.33	GO:0016787	hydrolase activity

0.37	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm
0.33	GO:0012505	endomembrane system

0.79

EC:2.7.4.9

GO:0004798

tr|T1G6Q0|T1G6Q0_HELRO
Uncharacterized protein
Search

0.51	GO:0055114	oxidation-reduction process
0.34	GO:0042618	poly-hydroxybutyrate metabolic process
0.34	GO:1901441	poly(hydroxyalkanoate) biosynthetic process

0.52	GO:0016491	oxidoreductase activity
0.39	GO:0004312	fatty acid synthase activity

0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.52

GO:0016491

tr|T1G6Q1|T1G6Q1_HELRO
Uncharacterized protein
Search

MSRA

0.43	Mitochondrial peptide methionine sulfoxide reductase

0.56	GO:0006464	cellular protein modification process
0.52	GO:0055114	oxidation-reduction process
0.34	GO:0007568	aging

0.77

GO:0008113

peptide-methionine (S)-S-oxide reductase activity

0.38	GO:0015629	actin cytoskeleton
0.38	GO:0005654	nucleoplasm
0.37	GO:0005829	cytosol
0.36	GO:0005739	mitochondrion
0.34	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.77

EC:1.8.4 EC:1.8.4.11

GO:0008113

tr|T1G6Q2|T1G6Q2_HELRO
Uncharacterized protein
Search

0.43	GO:2001253	regulation of histone H3-K36 trimethylation
0.42	GO:0010793	regulation of mRNA export from nucleus
0.40	GO:0050684	regulation of mRNA processing
0.40	GO:0032784	regulation of DNA-templated transcription, elongation
0.35	GO:0061564	axon development
0.34	GO:0035335	peptidyl-tyrosine dephosphorylation
0.34	GO:0042254	ribosome biogenesis

0.35	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.34	GO:0004725	protein tyrosine phosphatase activity
0.34	GO:0005198	structural molecule activity

0.61	GO:0005634	nucleus
0.36	GO:0005883	neurofilament
0.30	GO:0031224	intrinsic component of membrane

0.35

GO:0008138

tr|T1G6Q3|T1G6Q3_HELRO
Uncharacterized protein
Search

CASK

0.74	Peripheral plasma membrane protein CASK

0.63	GO:0006468	protein phosphorylation
0.42	GO:0051050	positive regulation of transport
0.42	GO:0010839	negative regulation of keratinocyte proliferation
0.41	GO:0001953	negative regulation of cell-matrix adhesion
0.41	GO:0090279	regulation of calcium ion import
0.41	GO:0061045	negative regulation of wound healing
0.41	GO:0070509	calcium ion import
0.40	GO:0090288	negative regulation of cellular response to growth factor stimulus
0.40	GO:0050807	regulation of synapse organization
0.40	GO:0016080	synaptic vesicle targeting

0.64	GO:0004672	protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0042043	neurexin family protein binding
0.39	GO:0005516	calmodulin binding
0.36	GO:0030165	PDZ domain binding
0.36	GO:0008022	protein C-terminus binding
0.35	GO:0032403	protein complex binding

0.42	GO:0005652	nuclear lamina
0.41	GO:0045202	synapse
0.41	GO:0016363	nuclear matrix
0.40	GO:0016323	basolateral plasma membrane
0.40	GO:0005604	basement membrane
0.39	GO:0043005	neuron projection
0.39	GO:0005911	cell-cell junction
0.39	GO:0120038	plasma membrane bounded cell projection part
0.39	GO:0005730	nucleolus
0.38	GO:0031982	vesicle

tr|T1G6Q4|T1G6Q4_HELRO
Uncharacterized protein
Search

0.80	Zinc metalloproteinase/disintegrin (Fragment)

0.60	GO:0006508	proteolysis
0.48	GO:0007229	integrin-mediated signaling pathway
0.46	GO:0009405	pathogenesis
0.41	GO:0006915	apoptotic process
0.40	GO:0007338	single fertilization
0.37	GO:0007155	cell adhesion
0.37	GO:0010604	positive regulation of macromolecule metabolic process
0.36	GO:0043085	positive regulation of catalytic activity
0.36	GO:0034241	positive regulation of macrophage fusion
0.36	GO:0042117	monocyte activation

0.69	GO:0004222	metalloendopeptidase activity
0.51	GO:0046872	metal ion binding
0.49	GO:0090729	toxin activity
0.38	GO:0052689	carboxylic ester hydrolase activity
0.35	GO:0016504	peptidase activator activity
0.35	GO:0043236	laminin binding
0.35	GO:0005178	integrin binding
0.35	GO:0005518	collagen binding
0.34	GO:0017124	SH3 domain binding

0.44	GO:0005576	extracellular region
0.36	GO:0005739	mitochondrion
0.35	GO:0005886	plasma membrane
0.34	GO:0009986	cell surface
0.33	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.69	EC:3.4.24	GO:0004222
0.38	KEGG:R00630	GO:0052689

tr|T1G6Q5|T1G6Q5_HELRO
Uncharacterized protein
Search

0.89	Pre-B-cell leukemia transcription factor

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.46	GO:0001654	eye development
0.46	GO:0061061	muscle structure development
0.46	GO:0007420	brain development
0.44	GO:0048468	cell development
0.44	GO:0001742	oenocyte differentiation
0.44	GO:0000060	protein import into nucleus, translocation
0.43	GO:0042659	regulation of cell fate specification

0.61	GO:0003700	DNA binding transcription factor activity
0.61	GO:0043565	sequence-specific DNA binding
0.42	GO:0033613	activating transcription factor binding
0.42	GO:0035326	enhancer binding
0.41	GO:0003713	transcription coactivator activity
0.40	GO:0046982	protein heterodimerization activity

0.61	GO:0005634	nucleus
0.41	GO:0005667	transcription factor complex
0.39	GO:0032993	protein-DNA complex
0.35	GO:0005737	cytoplasm
0.34	GO:0000444	MIS12/MIND type complex
0.34	GO:0001741	XY body
0.33	GO:0097708	intracellular vesicle
0.33	GO:0098805	whole membrane
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0012505	endomembrane system

tr|T1G6Q6|T1G6Q6_HELRO
Uncharacterized protein
Search

0.60	GO:0006508	proteolysis
0.60	GO:0006915	apoptotic process
0.48	GO:0070997	neuron death
0.46	GO:0009411	response to UV
0.46	GO:0007507	heart development
0.43	GO:0051604	protein maturation
0.43	GO:0007186	G-protein coupled receptor signaling pathway
0.39	GO:0042981	regulation of apoptotic process

0.75	GO:0004197	cysteine-type endopeptidase activity
0.44	GO:0004930	G-protein coupled receptor activity
0.43	GO:0070001	aspartic-type peptidase activity

0.37	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.75

EC:3.4.22

GO:0004197

tr|T1G6Q7|T1G6Q7_HELRO
Uncharacterized protein
Search

0.53	GO:0016567	protein ubiquitination
0.52	GO:0016310	phosphorylation
0.46	GO:0006511	ubiquitin-dependent protein catabolic process
0.36	GO:0048920	posterior lateral line neuromast primordium migration
0.36	GO:0070997	neuron death
0.33	GO:0007165	signal transduction

0.54	GO:0016301	kinase activity
0.53	GO:0004842	ubiquitin-protein transferase activity
0.47	GO:0061659	ubiquitin-like protein ligase activity
0.39	GO:0032947	protein complex scaffold activity
0.38	GO:0016874	ligase activity
0.36	GO:0051393	alpha-actinin binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.39	GO:0005923	bicellular tight junction
0.35	GO:0005912	adherens junction
0.34	GO:0042995	cell projection
0.33	GO:0005634	nucleus
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.38	EC:6	GO:0016874
0.53	KEGG:R03876	GO:0004842

tr|T1G6Q8|T1G6Q8_HELRO
alpha-1,2-Mannosidase
Search

MAN1A2

0.47	Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB

0.48	GO:0007585	respiratory gaseous exchange
0.48	GO:0048286	lung alveolus development
0.46	GO:0009100	glycoprotein metabolic process
0.36	GO:0043413	macromolecule glycosylation
0.35	GO:0035010	encapsulation of foreign target
0.34	GO:0072347	response to anesthetic
0.34	GO:1901137	carbohydrate derivative biosynthetic process
0.34	GO:0008340	determination of adult lifespan
0.34	GO:0036211	protein modification process
0.34	GO:0044267	cellular protein metabolic process

0.82	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
0.70	GO:0005509	calcium ion binding

0.47	GO:0000139	Golgi membrane
0.41	GO:0005783	endoplasmic reticulum
0.36	GO:0070062	extracellular exosome
0.34	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.82	EC:3.2.1.113	GO:0004571
0.82	KEGG:R05982 KEGG:R06722	GO:0004571

tr|T1G6Q9|T1G6Q9_HELRO
Uncharacterized protein
Search

tr|T1G6R0|T1G6R0_HELRO
Uncharacterized protein
Search

UNC119B

0.91	Unc-119 lipid binding chaperone B

0.73	GO:0007399	nervous system development
0.53	GO:0070121	Kupffer's vesicle development
0.50	GO:0042953	lipoprotein transport
0.47	GO:0060271	cilium assembly
0.46	GO:0061098	positive regulation of protein tyrosine kinase activity
0.45	GO:0030154	cell differentiation
0.45	GO:0007601	visual perception
0.43	GO:0043051	regulation of pharyngeal pumping
0.42	GO:0040024	dauer larval development
0.42	GO:0046662	regulation of oviposition

0.44	GO:0008289	lipid binding
0.35	GO:0051500	D-tyrosyl-tRNA(Tyr) deacylase activity
0.34	GO:0000049	tRNA binding
0.33	GO:0005515	protein binding

0.43	GO:0120025	plasma membrane bounded cell projection
0.42	GO:0045171	intercellular bridge
0.42	GO:0051233	spindle midzone
0.41	GO:0000922	spindle pole
0.41	GO:0005813	centrosome
0.40	GO:0097458	neuron part
0.38	GO:0044463	cell projection part
0.35	GO:0042765	GPI-anchor transamidase complex

tr|T1G6R1|T1G6R1_HELRO
Uncharacterized protein
Search

tr|T1G6R2|T1G6R2_HELRO
Uncharacterized protein
Search

0.43	GO:2001253	regulation of histone H3-K36 trimethylation
0.43	GO:0010793	regulation of mRNA export from nucleus
0.40	GO:0050684	regulation of mRNA processing
0.40	GO:0032784	regulation of DNA-templated transcription, elongation
0.35	GO:0061564	axon development
0.34	GO:0042254	ribosome biogenesis
0.32	GO:0055085	transmembrane transport

0.33	GO:0005198	structural molecule activity
0.33	GO:0022857	transmembrane transporter activity

0.61	GO:0005634	nucleus
0.35	GO:0005883	neurofilament
0.30	GO:0031224	intrinsic component of membrane

tr|T1G6R3|T1G6R3_HELRO
Uncharacterized protein
Search

0.10	NADP-dependent 3-hydroxy acid dehydrogenase YdfG

0.52	GO:0055114	oxidation-reduction process
0.43	GO:0006633	fatty acid biosynthetic process
0.32	GO:0055085	transmembrane transport

0.53	GO:0016491	oxidoreductase activity
0.49	GO:0004312	fatty acid synthase activity
0.43	GO:0051287	NAD binding

0.30

GO:0044425

membrane part

0.53

GO:0016491

tr|T1G6R4|T1G6R4_HELRO
Uncharacterized protein
Search

0.84	GO:1904247	positive regulation of polynucleotide adenylyltransferase activity
0.45	GO:0042981	regulation of apoptotic process
0.44	GO:0071222	cellular response to lipopolysaccharide
0.44	GO:0006915	apoptotic process
0.43	GO:0000165	MAPK cascade
0.43	GO:0016973	poly(A)+ mRNA export from nucleus
0.41	GO:0043069	negative regulation of programmed cell death
0.38	GO:0031124	mRNA 3'-end processing
0.37	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.37	GO:0043631	RNA polyadenylation

0.59	GO:0003723	RNA binding
0.43	GO:0097718	disordered domain specific binding
0.42	GO:0070063	RNA polymerase binding
0.40	GO:0046982	protein heterodimerization activity
0.40	GO:0042802	identical protein binding
0.36	GO:0043621	protein self-association
0.36	GO:0005509	calcium ion binding

0.45	GO:0042405	nuclear inclusion body
0.44	GO:0097136	Bcl-2 family protein complex
0.40	GO:0016604	nuclear body
0.39	GO:0030529	intracellular ribonucleoprotein complex
0.37	GO:0000790	nuclear chromatin
0.37	GO:0005730	nucleolus
0.35	GO:0005741	mitochondrial outer membrane
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1G6R5|T1G6R5_HELRO
Uncharacterized protein
Search

0.93	Putative nadh:ubiquinone dehydrogenase

0.53

GO:0055114

oxidation-reduction process

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.61	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0008137

tr|T1G6R6|T1G6R6_HELRO
Uncharacterized protein
Search

CROP

0.82	Cisplatin resistance-associated overexpressed protein (Fragment)

0.84	GO:0006376	mRNA splice site selection
0.33	GO:0046579	positive regulation of Ras protein signal transduction
0.33	GO:0070374	positive regulation of ERK1 and ERK2 cascade

0.76	GO:0003729	mRNA binding
0.34	GO:0003677	DNA binding
0.33	GO:0005515	protein binding

0.82	GO:0005685	U1 snRNP
0.49	GO:0016607	nuclear speck
0.46	GO:0071004	U2-type prespliceosome
0.30	GO:0016020	membrane

tr|T1G6R7|T1G6R7_HELRO
Uncharacterized protein
Search

0.53	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.53	GO:0000209	protein polyubiquitination
0.51	GO:0045471	response to ethanol
0.51	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.47	GO:0001172	transcription, RNA-templated
0.47	GO:0039694	viral RNA genome replication

0.52	GO:0008139	nuclear localization sequence binding
0.50	GO:0061630	ubiquitin protein ligase activity
0.50	GO:0043130	ubiquitin binding
0.50	GO:0016874	ligase activity
0.47	GO:0003968	RNA-directed 5'-3' RNA polymerase activity
0.43	GO:0008270	zinc ion binding
0.42	GO:0003723	RNA binding

0.30

GO:0016020

membrane

0.50

GO:0016874

tr|T1G6R8|T1G6R8_HELRO
Uncharacterized protein
Search

0.76	Synaptic vesicular amine transporter

0.55	GO:0055085	transmembrane transport
0.54	GO:0015893	drug transport
0.50	GO:0015844	monoamine transport
0.49	GO:0015842	aminergic neurotransmitter loading into synaptic vesicle
0.47	GO:1904647	response to rotenone
0.47	GO:1904340	positive regulation of dopaminergic neuron differentiation
0.46	GO:0051608	histamine transport
0.46	GO:0015850	organic hydroxy compound transport
0.40	GO:0007610	behavior
0.38	GO:0001975	response to amphetamine

0.54	GO:0015238	drug transmembrane transporter activity
0.49	GO:0008504	monoamine transmembrane transporter activity
0.41	GO:1901618	organic hydroxy compound transmembrane transporter activity
0.41	GO:0005326	neurotransmitter transporter activity
0.41	GO:0008519	ammonium transmembrane transporter activity
0.36	GO:0005549	odorant binding
0.35	GO:0004984	olfactory receptor activity
0.34	GO:0005249	voltage-gated potassium channel activity

0.47	GO:0098793	presynapse
0.45	GO:0070382	exocytic vesicle
0.43	GO:0031594	neuromuscular junction
0.38	GO:0005887	integral component of plasma membrane
0.34	GO:0031011	Ino80 complex
0.34	GO:0034705	potassium channel complex

tr|T1G6R9|T1G6R9_HELRO
Uncharacterized protein
Search

tr|T1G6S0|T1G6S0_HELRO
Uncharacterized protein
Search

0.70	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.45	GO:0030522	intracellular receptor signaling pathway
0.36	GO:0061066	positive regulation of dauer larval development
0.36	GO:0070781	response to biotin
0.36	GO:0043051	regulation of pharyngeal pumping
0.36	GO:0043327	chemotaxis to cAMP

0.65	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.60	GO:0003707	steroid hormone receptor activity
0.33	GO:0003682	chromatin binding
0.33	GO:0044212	transcription regulatory region DNA binding
0.33	GO:0003690	double-stranded DNA binding
0.32	GO:0008168	methyltransferase activity
0.32	GO:0004672	protein kinase activity
0.32	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.33	GO:0005667	transcription factor complex
0.33	GO:0005615	extracellular space
0.32	GO:0005739	mitochondrion
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.32

GO:0008168

tr|T1G6S1|T1G6S1_HELRO
Uncharacterized protein
Search

0.61	Pheromone biosynthesis-activating neuropeptide receptor subtype C

0.74	GO:0007218	neuropeptide signaling pathway
0.34	GO:0002430	complement receptor mediated signaling pathway
0.33	GO:0007217	tachykinin receptor signaling pathway
0.33	GO:0006935	chemotaxis
0.33	GO:0006468	protein phosphorylation
0.32	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.32	GO:0050900	leukocyte migration
0.32	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.32	GO:0006954	inflammatory response
0.32	GO:0070887	cellular response to chemical stimulus

0.80	GO:0001607	neuromedin U receptor activity
0.35	GO:0050254	rhodopsin kinase activity
0.34	GO:0004876	complement component C3a receptor activity
0.34	GO:0030273	melanin-concentrating hormone receptor activity
0.34	GO:0004995	tachykinin receptor activity

0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.35

EC:2.7.11.14

GO:0050254

tr|T1G6S2|T1G6S2_HELRO
Uncharacterized protein
Search

WASF2

0.64	WAS protein family member 2

0.74	GO:0030036	actin cytoskeleton organization
0.58	GO:0030032	lamellipodium assembly
0.55	GO:0031643	positive regulation of myelination
0.54	GO:0014003	oligodendrocyte development
0.47	GO:0051128	regulation of cellular component organization
0.47	GO:0022603	regulation of anatomical structure morphogenesis
0.45	GO:0072673	lamellipodium morphogenesis
0.45	GO:0035855	megakaryocyte development
0.45	GO:0016601	Rac protein signal transduction
0.44	GO:0065008	regulation of biological quality

0.71	GO:0003779	actin binding
0.45	GO:0051018	protein kinase A binding
0.44	GO:0045296	cadherin binding
0.43	GO:0017124	SH3 domain binding
0.42	GO:0032403	protein complex binding

0.69	GO:0005856	cytoskeleton
0.56	GO:0030027	lamellipodium
0.45	GO:0031209	SCAR complex
0.43	GO:0001726	ruffle
0.43	GO:0005769	early endosome
0.42	GO:0005911	cell-cell junction
0.36	GO:0070062	extracellular exosome
0.33	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

tr|T1G6S3|T1G6S3_HELRO
Uncharacterized protein
Search

0.68	Chlorophyllide a oxygenase

0.53	GO:0055114	oxidation-reduction process
0.39	GO:0045456	ecdysteroid biosynthetic process
0.39	GO:0002168	instar larval development
0.38	GO:0035264	multicellular organism growth
0.38	GO:0007552	metamorphosis
0.33	GO:0019439	aromatic compound catabolic process

0.71	GO:0051537	2 iron, 2 sulfur cluster binding
0.54	GO:0016491	oxidoreductase activity
0.36	GO:0005506	iron ion binding
0.34	GO:0016788	hydrolase activity, acting on ester bonds

0.30

GO:0044425

membrane part

0.54

GO:0016491

tr|T1G6S4|T1G6S4_HELRO
Uncharacterized protein
Search

0.66	GTP-binding protein homolog1

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0032553	ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

tr|T1G6S5|T1G6S5_HELRO
Uncharacterized protein
Search

tr|T1G6S6|T1G6S6_HELRO
Uncharacterized protein
Search

0.51	Amino-terminal enhancer of split

0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:0010468	regulation of gene expression

0.60	GO:0005634	nucleus
0.35	GO:0005925	focal adhesion
0.33	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

tr|T1G6S7|T1G6S7_HELRO
Uncharacterized protein
Search

0.39	Oxysterol-binding protein-related protein 9

0.73	GO:0006869	lipid transport
0.36	GO:0006886	intracellular protein transport
0.35	GO:0006699	bile acid biosynthetic process
0.34	GO:0015850	organic hydroxy compound transport
0.33	GO:0050909	sensory perception of taste
0.32	GO:0007165	signal transduction

0.38	GO:0017137	Rab GTPase binding
0.37	GO:0008289	lipid binding
0.35	GO:0015248	sterol transporter activity
0.32	GO:0004871	signal transducer activity

0.44	GO:0005794	Golgi apparatus
0.43	GO:0005829	cytosol
0.37	GO:0031902	late endosome membrane
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1G6S8|T1G6S8_HELRO
Uncharacterized protein
Search

PRMT3

0.81	Probable HMT1-hnRNP arginine N-methyltransferase

0.70	GO:0008213	protein alkylation
0.65	GO:0043414	macromolecule methylation
0.54	GO:0031397	negative regulation of protein ubiquitination
0.54	GO:0018195	peptidyl-arginine modification
0.44	GO:0016570	histone modification
0.38	GO:1903506	regulation of nucleic acid-templated transcription
0.38	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.38	GO:0010468	regulation of gene expression
0.35	GO:0060997	dendritic spine morphogenesis
0.34	GO:0042254	ribosome biogenesis

0.61	GO:0008168	methyltransferase activity
0.43	GO:0140096	catalytic activity, acting on a protein
0.40	GO:0003676	nucleic acid binding
0.34	GO:0043022	ribosome binding
0.34	GO:0005515	protein binding
0.34	GO:0072341	modified amino acid binding
0.34	GO:0046872	metal ion binding
0.33	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.33	GO:0051287	NAD binding

0.48	GO:0005829	cytosol
0.44	GO:0005840	ribosome
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.61

GO:0008168

tr|T1G6S9|T1G6S9_HELRO
Uncharacterized protein
Search

0.74	Synaptic vesicular amine transporter

0.57	GO:0006855	drug transmembrane transport
0.49	GO:0015844	monoamine transport
0.48	GO:0015842	aminergic neurotransmitter loading into synaptic vesicle
0.47	GO:1904647	response to rotenone
0.46	GO:1904340	positive regulation of dopaminergic neuron differentiation
0.46	GO:0051608	histamine transport
0.45	GO:0015850	organic hydroxy compound transport
0.41	GO:0001975	response to amphetamine
0.40	GO:0007610	behavior
0.39	GO:0009791	post-embryonic development

0.57	GO:0015238	drug transmembrane transporter activity
0.48	GO:0008504	monoamine transmembrane transporter activity
0.43	GO:0016746	transferase activity, transferring acyl groups
0.41	GO:1901618	organic hydroxy compound transmembrane transporter activity
0.40	GO:0005326	neurotransmitter transporter activity
0.40	GO:0008519	ammonium transmembrane transporter activity
0.34	GO:0005249	voltage-gated potassium channel activity

0.46	GO:0098793	presynapse
0.44	GO:0070382	exocytic vesicle
0.43	GO:0031594	neuromuscular junction
0.37	GO:0005887	integral component of plasma membrane
0.34	GO:0031011	Ino80 complex
0.34	GO:0034705	potassium channel complex

0.43

EC:2.3

GO:0016746

tr|T1G6T0|T1G6T0_HELRO
Uncharacterized protein
Search

TYMS

0.42	Bifunctional dihydrofolate reductase-thymidylate synthase

0.78	GO:0006231	dTMP biosynthetic process
0.63	GO:0032259	methylation
0.58	GO:0046654	tetrahydrofolate biosynthetic process
0.57	GO:0006730	one-carbon metabolic process
0.44	GO:0055114	oxidation-reduction process
0.43	GO:0006235	dTTP biosynthetic process
0.41	GO:0046683	response to organophosphorus
0.39	GO:0017148	negative regulation of translation
0.36	GO:0019088	immortalization of host cell by virus
0.35	GO:0060574	intestinal epithelial cell maturation

0.79	GO:0004799	thymidylate synthase activity
0.61	GO:0004146	dihydrofolate reductase activity
0.42	GO:1990825	sequence-specific mRNA binding
0.42	GO:0000900	translation repressor activity, nucleic acid binding
0.36	GO:0019212	phosphatase inhibitor activity
0.36	GO:0004633	phosphopantothenoylcysteine decarboxylase activity
0.35	GO:0005542	folic acid binding
0.35	GO:0010181	FMN binding
0.34	GO:0042803	protein homodimerization activity

0.39	GO:0005759	mitochondrial matrix
0.37	GO:0005634	nucleus
0.36	GO:0031966	mitochondrial membrane
0.36	GO:0019866	organelle inner membrane
0.33	GO:0005829	cytosol
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0044425	membrane part

0.79	EC:2.1.1.45	GO:0004799
0.79	KEGG:R02101	GO:0004799

tr|T1G6T1|T1G6T1_HELRO
Uncharacterized protein
Search

TSC22D4

0.68	TSC22 domain family protein 3

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.44	GO:0070236	negative regulation of activation-induced cell death of T cells
0.36	GO:0006970	response to osmotic stress
0.35	GO:0048642	negative regulation of skeletal muscle tissue development
0.34	GO:0051253	negative regulation of RNA metabolic process
0.34	GO:0010558	negative regulation of macromolecule biosynthetic process
0.34	GO:0031327	negative regulation of cellular biosynthetic process
0.34	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification

0.61	GO:0003700	DNA binding transcription factor activity
0.35	GO:0043426	MRF binding
0.34	GO:0017095	heparan sulfate 6-O-sulfotransferase activity

0.40	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.34

EC:2.8.2

GO:0017095

tr|T1G6T2|T1G6T2_HELRO
Uncharacterized protein
Search

0.74	Endoplasmic reticulum resident protein 29

0.70	GO:0009306	protein secretion
0.38	GO:0000187	activation of MAPK activity
0.38	GO:0050709	negative regulation of protein secretion
0.38	GO:0006886	intracellular protein transport
0.38	GO:0006457	protein folding
0.36	GO:0010628	positive regulation of gene expression
0.36	GO:0007186	G-protein coupled receptor signaling pathway
0.36	GO:0010629	negative regulation of gene expression

0.36	GO:0004930	G-protein coupled receptor activity
0.32	GO:0016740	transferase activity

0.84	GO:0005788	endoplasmic reticulum lumen
0.37	GO:0009986	cell surface
0.30	GO:0016020	membrane

0.32

GO:0016740

tr|T1G6T3|T1G6T3_HELRO
Uncharacterized protein
Search

0.56	Synaptic vesicular amine transporter

0.59	GO:0006855	drug transmembrane transport
0.51	GO:0015844	monoamine transport
0.51	GO:0015842	aminergic neurotransmitter loading into synaptic vesicle
0.50	GO:1904647	response to rotenone
0.50	GO:1904340	positive regulation of dopaminergic neuron differentiation
0.49	GO:0051608	histamine transport
0.48	GO:0015850	organic hydroxy compound transport
0.41	GO:0007610	behavior
0.41	GO:0001975	response to amphetamine
0.39	GO:0009791	post-embryonic development

0.59	GO:0015238	drug transmembrane transporter activity
0.51	GO:0008504	monoamine transmembrane transporter activity
0.42	GO:1901618	organic hydroxy compound transmembrane transporter activity
0.41	GO:0005326	neurotransmitter transporter activity
0.41	GO:0008519	ammonium transmembrane transporter activity
0.34	GO:0005249	voltage-gated potassium channel activity

0.48	GO:0098793	presynapse
0.47	GO:0070382	exocytic vesicle
0.45	GO:0031594	neuromuscular junction
0.38	GO:0005887	integral component of plasma membrane
0.35	GO:0031011	Ino80 complex
0.34	GO:0034705	potassium channel complex

tr|T1G6T4|T1G6T4_HELRO
Uncharacterized protein
Search

0.77	Cerebral cavernous malformation 3

0.78	GO:0060439	trachea morphogenesis
0.54	GO:2001137	positive regulation of endocytic recycling
0.53	GO:1903358	regulation of Golgi organization
0.50	GO:0007029	endoplasmic reticulum organization
0.49	GO:0060562	epithelial tube morphogenesis
0.47	GO:0043547	positive regulation of GTPase activity
0.43	GO:0003007	heart morphogenesis
0.43	GO:0048514	blood vessel morphogenesis
0.42	GO:0043009	chordate embryonic development
0.42	GO:0000398	mRNA splicing, via spliceosome

0.48	GO:0019901	protein kinase binding
0.36	GO:0046872	metal ion binding

0.53	GO:0098592	cytoplasmic side of apical plasma membrane
0.51	GO:0035838	growing cell tip
0.44	GO:0071013	catalytic step 2 spliceosome
0.37	GO:0005737	cytoplasm

tr|T1G6T5|T1G6T5_HELRO
Uncharacterized protein
Search

0.55	Neuropeptide Y receptor

0.69	GO:0007186	G-protein coupled receptor signaling pathway
0.38	GO:1901652	response to peptide
0.38	GO:0035587	purinergic receptor signaling pathway
0.37	GO:0032870	cellular response to hormone stimulus
0.36	GO:0007631	feeding behavior
0.36	GO:2000479	regulation of cAMP-dependent protein kinase activity
0.36	GO:0007268	chemical synaptic transmission
0.36	GO:0045761	regulation of adenylate cyclase activity
0.36	GO:0008015	blood circulation
0.35	GO:0043408	regulation of MAPK cascade

0.72	GO:0008528	G-protein coupled peptide receptor activity
0.45	GO:0042277	peptide binding
0.38	GO:0001609	G-protein coupled adenosine receptor activity
0.38	GO:0042562	hormone binding
0.37	GO:0031628	opioid receptor binding
0.34	GO:0008484	sulfuric ester hydrolase activity
0.33	GO:0004997	thyrotropin-releasing hormone receptor activity
0.33	GO:0004333	fumarate hydratase activity
0.31	GO:0016740	transferase activity

0.36	GO:0005887	integral component of plasma membrane
0.34	GO:0015629	actin cytoskeleton
0.33	GO:0043005	neuron projection
0.33	GO:0045239	tricarboxylic acid cycle enzyme complex
0.33	GO:0005681	spliceosomal complex

0.34	EC:3.1.6	GO:0008484
0.33	KEGG:R01082	GO:0004333

tr|T1G6T6|T1G6T6_HELRO
Uncharacterized protein
Search

0.57	Transducin like enhancer of split 2

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.39	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.38	GO:0051253	negative regulation of RNA metabolic process
0.38	GO:0010558	negative regulation of macromolecule biosynthetic process
0.38	GO:0031327	negative regulation of cellular biosynthetic process
0.36	GO:2000811	negative regulation of anoikis
0.36	GO:0045879	negative regulation of smoothened signaling pathway
0.36	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling

0.40	GO:0003714	transcription corepressor activity
0.38	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.37	GO:0071906	CRD domain binding
0.37	GO:0001104	RNA polymerase II transcription cofactor activity
0.37	GO:0070491	repressing transcription factor binding
0.36	GO:0071837	HMG box domain binding
0.35	GO:0042802	identical protein binding
0.34	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.34	GO:0003682	chromatin binding

0.61	GO:0005634	nucleus
0.43	GO:0005925	focal adhesion
0.40	GO:0031974	membrane-enclosed lumen
0.38	GO:0044446	intracellular organelle part
0.36	GO:0005667	transcription factor complex
0.35	GO:0005615	extracellular space
0.34	GO:0005829	cytosol

tr|T1G6T7|T1G6T7_HELRO
Oxysterol-binding protein
Search

0.38	Oxysterol-binding protein (Fragment)

0.74	GO:0006869	lipid transport
0.57	GO:0010890	positive regulation of sequestering of triglyceride
0.54	GO:0045444	fat cell differentiation
0.35	GO:0061737	leukotriene signaling pathway
0.34	GO:0006886	intracellular protein transport

0.37	GO:0008289	lipid binding
0.35	GO:0017137	Rab GTPase binding
0.35	GO:0004974	leukotriene receptor activity
0.32	GO:0043168	anion binding

0.49	GO:0005794	Golgi apparatus
0.48	GO:0005654	nucleoplasm
0.38	GO:0031902	late endosome membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1G6T8|T1G6T8_HELRO
Uncharacterized protein
Search

0.86	transmembrane protein 256 homolog isoform X2

0.30

GO:0044425

membrane part

tr|T1G6T9|T1G6T9_HELRO
Uncharacterized protein
Search

0.79

GO:0006004

fucose metabolic process

0.80

GO:0004560

alpha-L-fucosidase activity

0.80

EC:3.2.1.51

GO:0004560

tr|T1G6U0|T1G6U0_HELRO
Uncharacterized protein
Search

PTPN11

0.57	Tyrosine-protein phosphatase non-receptor type

0.75	GO:0035335	peptidyl-tyrosine dephosphorylation
0.54	GO:0051463	negative regulation of cortisol secretion
0.53	GO:0060125	negative regulation of growth hormone secretion
0.53	GO:0061582	intestinal epithelial cell migration
0.53	GO:0033277	abortive mitotic cell cycle
0.52	GO:0036302	atrioventricular canal development
0.52	GO:2001275	positive regulation of glucose import in response to insulin stimulus
0.52	GO:0033629	negative regulation of cell adhesion mediated by integrin
0.52	GO:0060020	Bergmann glial cell differentiation
0.51	GO:0071364	cellular response to epidermal growth factor stimulus

0.75	GO:0004725	protein tyrosine phosphatase activity
0.51	GO:0051428	peptide hormone receptor binding
0.51	GO:0005158	insulin receptor binding
0.51	GO:0005070	SH3/SH2 adaptor activity
0.50	GO:0030971	receptor tyrosine kinase binding
0.48	GO:0050839	cell adhesion molecule binding
0.36	GO:0031748	D1 dopamine receptor binding
0.36	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.36	GO:0043274	phospholipase binding
0.36	GO:0043560	insulin receptor substrate binding

0.42	GO:0005737	cytoplasm
0.42	GO:0005634	nucleus
0.41	GO:0043234	protein complex
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.75	EC:3.1.3.48	GO:0004725
0.36	KEGG:R04545	GO:0046934

tr|T1G6U1|T1G6U1_HELRO
Uncharacterized protein
Search

OTUD7B

0.68	OTU deubiquitinase 7B

0.66	GO:0035871	protein K11-linked deubiquitination
0.57	GO:0032717	negative regulation of interleukin-8 production
0.57	GO:0070536	protein K63-linked deubiquitination
0.56	GO:0071108	protein K48-linked deubiquitination
0.56	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling
0.55	GO:0002385	mucosal immune response
0.55	GO:1900181	negative regulation of protein localization to nucleus
0.52	GO:0000122	negative regulation of transcription by RNA polymerase II
0.49	GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process
0.44	GO:0007219	Notch signaling pathway

0.59	GO:0008270	zinc ion binding
0.56	GO:0070530	K63-linked polyubiquitin modification-dependent protein binding
0.55	GO:1990380	Lys48-specific deubiquitinase activity
0.54	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.52	GO:0003677	DNA binding

0.45	GO:0005634	nucleus
0.39	GO:0005737	cytoplasm

tr|T1G6U2|T1G6U2_HELRO
Uncharacterized protein
Search

MKNK2

0.87	MAP kinase-interacting serine/threonine-protein kinase 1

0.63	GO:0006468	protein phosphorylation
0.50	GO:0071243	cellular response to arsenic-containing substance
0.50	GO:0038034	signal transduction in absence of ligand
0.49	GO:0097191	extrinsic apoptotic signaling pathway
0.47	GO:0030097	hemopoiesis
0.47	GO:0018209	peptidyl-serine modification
0.44	GO:0035556	intracellular signal transduction
0.44	GO:0033138	positive regulation of peptidyl-serine phosphorylation
0.43	GO:0046580	negative regulation of Ras protein signal transduction
0.42	GO:0040008	regulation of growth

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0005516	calmodulin binding
0.45	GO:0051019	mitogen-activated protein kinase binding
0.35	GO:0046872	metal ion binding
0.32	GO:0003676	nucleic acid binding

0.46	GO:0044428	nuclear part
0.44	GO:0031974	membrane-enclosed lumen
0.42	GO:0005813	centrosome
0.41	GO:0005874	microtubule
0.39	GO:0012505	endomembrane system
0.38	GO:0031967	organelle envelope
0.37	GO:0005737	cytoplasm

tr|T1G6U3|T1G6U3_HELRO
Uncharacterized protein
Search

SOL-1

0.93	Suppressor of lurcher protein 1

0.62	GO:0001966	thigmotaxis
0.61	GO:0051968	positive regulation of synaptic transmission, glutamatergic
0.58	GO:0006972	hyperosmotic response
0.58	GO:0008344	adult locomotory behavior
0.54	GO:0040012	regulation of locomotion
0.49	GO:0065009	regulation of molecular function
0.44	GO:0006511	ubiquitin-dependent protein catabolic process
0.39	GO:0016310	phosphorylation
0.37	GO:0055114	oxidation-reduction process

0.57	GO:0016247	channel regulator activity
0.49	GO:0005201	extracellular matrix structural constituent
0.46	GO:0005509	calcium ion binding
0.45	GO:0004471	malate dehydrogenase (decarboxylating) (NAD+) activity
0.42	GO:0051287	NAD binding
0.41	GO:0004175	endopeptidase activity
0.40	GO:0005515	protein binding
0.40	GO:0008236	serine-type peptidase activity
0.40	GO:0016301	kinase activity
0.37	GO:0016874	ligase activity

0.59	GO:0032589	neuron projection membrane
0.59	GO:0008328	ionotropic glutamate receptor complex
0.53	GO:0045202	synapse
0.43	GO:0030054	cell junction

0.45	EC:1.1.1.38 EC:1.1.1.39	GO:0004471
0.45	KEGG:R00214	GO:0004471

tr|T1G6U4|T1G6U4_HELRO
Uncharacterized protein
Search

0.44	Potassium voltage-gated channel protein Shab

0.77	GO:0051260	protein homooligomerization
0.77	GO:0034765	regulation of ion transmembrane transport
0.73	GO:0071805	potassium ion transmembrane transport
0.35	GO:0060025	regulation of synaptic activity
0.35	GO:0045938	positive regulation of circadian sleep/wake cycle, sleep
0.35	GO:0008345	larval locomotory behavior
0.35	GO:0021591	ventricular system development
0.34	GO:0090504	epiboly
0.34	GO:0001508	action potential
0.34	GO:0008016	regulation of heart contraction

0.78	GO:0005249	voltage-gated potassium channel activity
0.34	GO:0042162	telomeric DNA binding
0.34	GO:0042803	protein homodimerization activity

0.78

GO:0008076

voltage-gated potassium channel complex

tr|T1G6U5|T1G6U5_HELRO
Uncharacterized protein
Search

TXNDC9

0.60	Thioredoxin domain-containing protein 9

0.69	GO:0045454	cell redox homeostasis
0.47	GO:0008616	queuosine biosynthetic process
0.34	GO:0016998	cell wall macromolecule catabolic process
0.34	GO:0009253	peptidoglycan catabolic process

0.59	GO:0045296	cadherin binding
0.49	GO:0008479	queuine tRNA-ribosyltransferase activity
0.35	GO:0003796	lysozyme activity

0.60	GO:0030496	midbody
0.57	GO:0005813	centrosome
0.51	GO:0005829	cytosol
0.48	GO:0005634	nucleus

0.49

EC:2.4.2.29

GO:0008479

tr|T1G6U6|T1G6U6_HELRO
Phospholipid scramblase
Search

0.61	Phospholipid scramblase

0.72

GO:0017121

phospholipid scrambling

0.75

GO:0017128

phospholipid scramblase activity

0.42	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

tr|T1G6U7|T1G6U7_HELRO
Uncharacterized protein
Search

SRSF2

0.73	Serine/arginine-rich splicing factor 2

0.65	GO:0043484	regulation of RNA splicing
0.38	GO:0050684	regulation of mRNA processing
0.38	GO:0008380	RNA splicing
0.37	GO:0006397	mRNA processing
0.36	GO:0033197	response to vitamin E
0.35	GO:0050482	arachidonic acid secretion
0.34	GO:0000278	mitotic cell cycle
0.34	GO:0007275	multicellular organism development
0.33	GO:0006644	phospholipid metabolic process
0.32	GO:0055114	oxidation-reduction process

0.59	GO:0003723	RNA binding
0.35	GO:0005080	protein kinase C binding
0.35	GO:0004623	phospholipase A2 activity
0.33	GO:0016874	ligase activity
0.33	GO:0008270	zinc ion binding
0.32	GO:0016491	oxidoreductase activity

0.40	GO:0016607	nuclear speck
0.38	GO:0005681	spliceosomal complex
0.37	GO:0005829	cytosol
0.36	GO:0035061	interchromatin granule
0.35	GO:0016605	PML body
0.35	GO:0070062	extracellular exosome
0.33	GO:0019013	viral nucleocapsid
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:3.1.1.4

GO:0004623

tr|T1G6U8|T1G6U8_HELRO
Phospholipid scramblase
Search

PLSCR1

0.67	Phospholipid scramblase

0.78	GO:0017121	phospholipid scrambling
0.64	GO:2000373	positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity
0.62	GO:0045071	negative regulation of viral genome replication
0.61	GO:0035456	response to interferon-beta
0.59	GO:0045089	positive regulation of innate immune response
0.57	GO:0006915	apoptotic process
0.57	GO:0051607	defense response to virus
0.55	GO:0006366	transcription by RNA polymerase II
0.55	GO:0060368	regulation of Fc receptor mediated stimulatory signaling pathway
0.54	GO:0045944	positive regulation of transcription by RNA polymerase II

0.80	GO:0017128	phospholipid scramblase activity
0.61	GO:0005154	epidermal growth factor receptor binding
0.58	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.57	GO:0017124	SH3 domain binding
0.57	GO:0042609	CD4 receptor binding
0.52	GO:0005509	calcium ion binding
0.52	GO:0019899	enzyme binding
0.37	GO:0003677	DNA binding

0.57	GO:0045121	membrane raft
0.54	GO:0031012	extracellular matrix
0.53	GO:0005730	nucleolus
0.53	GO:0005794	Golgi apparatus
0.52	GO:0005829	cytosol
0.50	GO:0005887	integral component of plasma membrane
0.42	GO:0070062	extracellular exosome

tr|T1G6U9|T1G6U9_HELRO
Uncharacterized protein
Search

0.63	Potassium voltage-gated channel protein Shab

0.73	GO:0034765	regulation of ion transmembrane transport
0.73	GO:0071805	potassium ion transmembrane transport
0.73	GO:0051260	protein homooligomerization
0.52	GO:1900454	positive regulation of long term synaptic depression
0.51	GO:0090314	positive regulation of protein targeting to membrane
0.50	GO:0046676	negative regulation of insulin secretion
0.50	GO:0098900	regulation of action potential
0.49	GO:0071333	cellular response to glucose stimulus
0.49	GO:0001508	action potential
0.42	GO:0021591	ventricular system development

0.78	GO:0005249	voltage-gated potassium channel activity
0.49	GO:0044325	ion channel binding
0.40	GO:0046982	protein heterodimerization activity
0.35	GO:0047485	protein N-terminus binding
0.34	GO:0042162	telomeric DNA binding
0.34	GO:0000149	SNARE binding
0.34	GO:0042803	protein homodimerization activity

0.78	GO:0008076	voltage-gated potassium channel complex
0.52	GO:0032809	neuronal cell body membrane
0.49	GO:0030425	dendrite
0.42	GO:0043204	perikaryon
0.40	GO:0016328	lateral plasma membrane
0.39	GO:0042383	sarcolemma
0.39	GO:0030424	axon
0.38	GO:0045211	postsynaptic membrane
0.38	GO:0030054	cell junction
0.35	GO:0044214	spanning component of plasma membrane

tr|T1G6V0|T1G6V0_HELRO
Uncharacterized protein
Search

tr|T1G6V1|T1G6V1_HELRO
Uncharacterized protein
Search

0.50	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.45	GO:0008380	RNA splicing
0.45	GO:0042981	regulation of apoptotic process
0.35	GO:0006397	mRNA processing
0.33	GO:0032988	ribonucleoprotein complex disassembly

0.56	GO:0003723	RNA binding
0.50	GO:0046872	metal ion binding
0.32	GO:0003677	DNA binding

0.43	GO:0005681	spliceosomal complex
0.36	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1G6V2|T1G6V2_HELRO
Uncharacterized protein
Search

MORN1

0.78	MORN repeat-containing protein 1

0.45	GO:0016310	phosphorylation
0.39	GO:0006508	proteolysis
0.39	GO:0016998	cell wall macromolecule catabolic process
0.38	GO:0009253	peptidoglycan catabolic process
0.38	GO:0046488	phosphatidylinositol metabolic process
0.37	GO:0030258	lipid modification
0.35	GO:0036211	protein modification process
0.34	GO:0044267	cellular protein metabolic process

0.47	GO:0016301	kinase activity
0.41	GO:0016805	dipeptidase activity
0.39	GO:0003796	lysozyme activity
0.37	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.36	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding

0.40	GO:0030314	junctional membrane complex
0.30	GO:0016020	membrane

0.41

EC:3.4.13

GO:0016805

tr|T1G6V3|T1G6V3_HELRO
Uncharacterized protein
Search

0.44	Fatty acid-binding protein, brain

0.72

GO:0008289

lipid binding

tr|T1G6V4|T1G6V4_HELRO
Uncharacterized protein
Search

tr|T1G6V5|T1G6V5_HELRO
Uncharacterized protein
Search

SNRPG

0.58	Small nuclear ribonucleoprotein polypeptide G

0.81	GO:0000387	spliceosomal snRNP assembly
0.35	GO:0008334	histone mRNA metabolic process
0.34	GO:0006369	termination of RNA polymerase II transcription
0.34	GO:0000245	spliceosomal complex assembly
0.34	GO:0051170	nuclear import
0.33	GO:0055114	oxidation-reduction process

0.41	GO:0003723	RNA binding
0.35	GO:0004148	dihydrolipoyl dehydrogenase activity
0.35	GO:1990446	U1 snRNP binding
0.33	GO:0070279	vitamin B6 binding
0.33	GO:0005515	protein binding
0.33	GO:0050662	coenzyme binding
0.32	GO:0043168	anion binding

0.76	GO:0005681	spliceosomal complex
0.60	GO:0019013	viral nucleocapsid
0.51	GO:0005687	U4 snRNP
0.51	GO:0034719	SMN-Sm protein complex
0.51	GO:0043186	P granule
0.50	GO:0005682	U5 snRNP
0.49	GO:0005686	U2 snRNP
0.49	GO:0005685	U1 snRNP
0.49	GO:0097526	spliceosomal tri-snRNP complex
0.42	GO:1902494	catalytic complex

0.35

EC:1.8.1.4

GO:0004148

tr|T1G6V6|T1G6V6_HELRO
Uncharacterized protein
Search

0.45	Proline synthase co-transcribed bacterial protein (Fragment)

0.34	GO:0000387	spliceosomal snRNP assembly
0.33	GO:0006913	nucleocytoplasmic transport
0.33	GO:0007186	G-protein coupled receptor signaling pathway
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.67	GO:0030170	pyridoxal phosphate binding
0.34	GO:0017056	structural constituent of nuclear pore
0.33	GO:0004930	G-protein coupled receptor activity
0.32	GO:0008270	zinc ion binding
0.32	GO:0003700	DNA binding transcription factor activity

0.42	GO:0005739	mitochondrion
0.36	GO:0070062	extracellular exosome
0.34	GO:0044428	nuclear part
0.33	GO:0012505	endomembrane system
0.33	GO:0032991	macromolecular complex
0.33	GO:0031967	organelle envelope
0.30	GO:0031224	intrinsic component of membrane

tr|T1G6V7|T1G6V7_HELRO
Uncharacterized protein
Search

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.70	GO:0007602	phototransduction
0.69	GO:0007601	visual perception
0.66	GO:0018298	protein-chromophore linkage
0.47	GO:0070098	chemokine-mediated signaling pathway
0.43	GO:0006935	chemotaxis
0.38	GO:0016038	absorption of visible light
0.37	GO:0007194	negative regulation of adenylate cyclase activity
0.36	GO:0071482	cellular response to light stimulus
0.36	GO:0009584	detection of visible light

0.72	GO:0004930	G-protein coupled receptor activity
0.70	GO:0009881	photoreceptor activity
0.49	GO:0001653	peptide receptor activity
0.46	GO:0004896	cytokine receptor activity
0.38	GO:0005502	11-cis retinal binding
0.37	GO:0019960	C-X3-C chemokine binding

0.38	GO:0097381	photoreceptor disc membrane
0.35	GO:0005887	integral component of plasma membrane
0.35	GO:0005654	nucleoplasm

tr|T1G6V8|T1G6V8_HELRO
Uncharacterized protein
Search

0.37	Long-chain-fatty-acid--CoA ligase

0.37	GO:0055114	oxidation-reduction process
0.37	GO:0006564	L-serine biosynthetic process
0.36	GO:0016311	dephosphorylation
0.34	GO:0008218	bioluminescence
0.34	GO:0006397	mRNA processing
0.33	GO:0006566	threonine metabolic process
0.33	GO:0001676	long-chain fatty acid metabolic process
0.33	GO:0006357	regulation of transcription by RNA polymerase II
0.32	GO:0016310	phosphorylation

0.48	GO:0016874	ligase activity
0.42	GO:0004497	monooxygenase activity
0.38	GO:0004647	phosphoserine phosphatase activity
0.34	GO:0004413	homoserine kinase activity
0.33	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.33	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
0.33	GO:0008270	zinc ion binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding

0.33	GO:0005576	extracellular region
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.48	EC:6	GO:0016874
0.34	KEGG:R01771	GO:0004413

tr|T1G6V9|T1G6V9_HELRO
Uncharacterized protein
Search

HMGB2

0.53	High mobility group box 2

0.56	GO:0002437	inflammatory response to antigenic stimulus
0.54	GO:0072091	regulation of stem cell proliferation
0.54	GO:0050830	defense response to Gram-positive bacterium
0.54	GO:0050829	defense response to Gram-negative bacterium
0.53	GO:0032496	response to lipopolysaccharide
0.51	GO:0050767	regulation of neurogenesis
0.50	GO:0045654	positive regulation of megakaryocyte differentiation
0.49	GO:0045648	positive regulation of erythrocyte differentiation
0.49	GO:0032075	positive regulation of nuclease activity
0.49	GO:0043388	positive regulation of DNA binding

0.56	GO:0044378	non-sequence-specific DNA binding, bending
0.55	GO:0097100	supercoiled DNA binding
0.54	GO:0001158	enhancer sequence-specific DNA binding
0.52	GO:0000400	four-way junction DNA binding
0.50	GO:0050786	RAGE receptor binding
0.49	GO:0042056	chemoattractant activity
0.48	GO:0008134	transcription factor binding
0.44	GO:0003684	damaged DNA binding
0.43	GO:0019904	protein domain specific binding
0.43	GO:0003697	single-stranded DNA binding

0.61	GO:0005634	nucleus
0.49	GO:0005615	extracellular space
0.48	GO:0000785	chromatin
0.47	GO:0048471	perinuclear region of cytoplasm
0.46	GO:0070013	intracellular organelle lumen
0.46	GO:0000793	condensed chromosome
0.40	GO:0043234	protein complex
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.34

GO:0032440

tr|T1G6W0|T1G6W0_HELRO
Hexosyltransferase
Search

0.43	Hexosyltransferase

0.74

GO:0006486

protein glycosylation

0.81

GO:0008378

galactosyltransferase activity

0.74	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

0.81

GO:0008378

tr|T1G6W1|T1G6W1_HELRO
Uncharacterized protein
Search

tr|T1G6W2|T1G6W2_HELRO
Uncharacterized protein
Search

0.30

GO:0044425

membrane part

tr|T1G6W3|T1G6W3_HELRO
Uncharacterized protein
Search

RAB3C

0.88	Ras-related protein Rab-3

0.56	GO:0017157	regulation of exocytosis
0.53	GO:0051944	positive regulation of catecholamine uptake involved in synaptic transmission
0.53	GO:0097494	regulation of vesicle size
0.53	GO:0018125	peptidyl-cysteine methylation
0.53	GO:0019882	antigen processing and presentation
0.53	GO:0051584	regulation of dopamine uptake involved in synaptic transmission
0.53	GO:0032226	positive regulation of synaptic transmission, dopaminergic
0.51	GO:2001025	positive regulation of response to drug
0.49	GO:0043270	positive regulation of ion transport
0.37	GO:0015031	protein transport

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.60	GO:0031489	myosin V binding
0.59	GO:0030742	GTP-dependent protein binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0046872	metal ion binding

0.56	GO:0008021	synaptic vesicle
0.55	GO:0048471	perinuclear region of cytoplasm
0.48	GO:0030141	secretory granule
0.38	GO:0099501	exocytic vesicle membrane
0.37	GO:0031225	anchored component of membrane
0.37	GO:0031300	intrinsic component of organelle membrane
0.37	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.35	GO:0005886	plasma membrane
0.33	GO:0043005	neuron projection

tr|T1G6W4|T1G6W4_HELRO
Uncharacterized protein
Search

CASK

0.82	Peripheral plasma membrane protein CASK

0.58	GO:0006468	protein phosphorylation
0.39	GO:0010839	negative regulation of keratinocyte proliferation
0.39	GO:0090280	positive regulation of calcium ion import
0.39	GO:0001953	negative regulation of cell-matrix adhesion
0.39	GO:0019098	reproductive behavior
0.38	GO:0061045	negative regulation of wound healing
0.38	GO:0097112	gamma-aminobutyric acid receptor clustering
0.38	GO:1903361	protein localization to basolateral plasma membrane
0.38	GO:0070509	calcium ion import
0.38	GO:0040026	positive regulation of vulval development

0.58	GO:0004672	protein kinase activity
0.51	GO:0030554	adenyl nucleotide binding
0.50	GO:0097367	carbohydrate derivative binding
0.50	GO:0008144	drug binding
0.50	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0042043	neurexin family protein binding
0.38	GO:0005159	insulin-like growth factor receptor binding
0.37	GO:0005516	calmodulin binding
0.35	GO:0030165	PDZ domain binding
0.35	GO:0008022	protein C-terminus binding

0.39	GO:0005652	nuclear lamina
0.39	GO:0030054	cell junction
0.38	GO:0016363	nuclear matrix
0.38	GO:0016323	basolateral plasma membrane
0.38	GO:0045202	synapse
0.38	GO:0005604	basement membrane
0.36	GO:0005730	nucleolus
0.36	GO:0031982	vesicle
0.36	GO:0098846	podocyte foot
0.36	GO:0005829	cytosol

0.34

EC:2.7.4.8

GO:0004385

tr|T1G6W5|T1G6W5_HELRO
Uncharacterized protein
Search

RFC5

0.72	Replication factor c / DNA polymerase iii gamma-tau subunit

0.65	GO:0006260	DNA replication
0.42	GO:0060041	retina development in camera-type eye
0.40	GO:1900264	positive regulation of DNA-directed DNA polymerase activity
0.38	GO:0006281	DNA repair
0.34	GO:0022616	DNA strand elongation
0.34	GO:0007062	sister chromatid cohesion
0.33	GO:0031348	negative regulation of defense response
0.33	GO:0080009	mRNA methylation
0.33	GO:0071897	DNA biosynthetic process
0.33	GO:0006370	7-methylguanosine mRNA capping

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0003677	DNA binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0033170	protein-DNA loading ATPase activity
0.39	GO:0043142	single-stranded DNA-dependent ATPase activity
0.37	GO:0019899	enzyme binding
0.34	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding

0.45	GO:0005663	DNA replication factor C complex
0.44	GO:0031391	Elg1 RFC-like complex
0.39	GO:0031390	Ctf18 RFC-like complex
0.37	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.33

EC:2.7.7.7

GO:0003887

tr|T1G6W6|T1G6W6_HELRO
Uncharacterized protein
Search

0.89	Solute carrier family 18, subfamily B, member 1

0.55

GO:0055085

transmembrane transport

0.41

GO:0005215

transporter activity

0.38

GO:0005887

integral component of plasma membrane

tr|T1G6W7|T1G6W7_HELRO
Uncharacterized protein
Search

tr|T1G6W8|T1G6W8_HELRO
Uncharacterized protein
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0.47	Microfibril-associated glycoprotein 4

0.76	GO:0007596	blood coagulation
0.55	GO:0001775	cell activation
0.54	GO:0051258	protein polymerization
0.52	GO:0043152	induction of bacterial agglutination
0.51	GO:0098609	cell-cell adhesion
0.51	GO:0034116	positive regulation of heterotypic cell-cell adhesion
0.51	GO:0042730	fibrinolysis
0.51	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.51	GO:0045907	positive regulation of vasoconstriction
0.51	GO:2000352	negative regulation of endothelial cell apoptotic process

0.56	GO:0030674	protein binding, bridging
0.53	GO:0005102	receptor binding
0.49	GO:0050839	cell adhesion molecule binding
0.47	GO:0051087	chaperone binding
0.42	GO:0005509	calcium ion binding
0.41	GO:0005198	structural molecule activity
0.40	GO:0004859	phospholipase inhibitor activity
0.38	GO:0046982	protein heterodimerization activity
0.38	GO:0030545	receptor regulator activity
0.38	GO:0032403	protein complex binding

0.60	GO:0005577	fibrinogen complex
0.51	GO:0031091	platelet alpha granule
0.48	GO:0009897	external side of plasma membrane
0.46	GO:0005938	cell cortex
0.44	GO:0005783	endoplasmic reticulum
0.38	GO:0005769	early endosome
0.37	GO:0005794	Golgi apparatus
0.30	GO:0016021	integral component of membrane

tr|T1G6W9|T1G6W9_HELRO
Uncharacterized protein
Search

0.63	Phosphoribosyl pyrophosphate synthetase-associated protein 2

0.65	GO:0009116	nucleoside metabolic process
0.64	GO:0009165	nucleotide biosynthetic process
0.40	GO:0016310	phosphorylation
0.34	GO:0015991	ATP hydrolysis coupled proton transport

0.78	GO:0004749	ribose phosphate diphosphokinase activity
0.64	GO:0000287	magnesium ion binding
0.41	GO:0016301	kinase activity
0.37	GO:0042802	identical protein binding
0.34	GO:0046961	proton-transporting ATPase activity, rotational mechanism

0.34	GO:0033180	proton-transporting V-type ATPase, V1 domain
0.30	GO:0016021	integral component of membrane

0.78	EC:2.7.6.1	GO:0004749
0.78	KEGG:R01049	GO:0004749

tr|T1G6X0|T1G6X0_HELRO
Uncharacterized protein
Search

0.58	Zinc finger MYM-type protein 1

0.35	GO:0006357	regulation of transcription by RNA polymerase II
0.34	GO:0007275	multicellular organism development
0.34	GO:0046080	dUTP metabolic process
0.33	GO:0016310	phosphorylation
0.33	GO:0006313	transposition, DNA-mediated

0.68	GO:0046983	protein dimerization activity
0.36	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.34	GO:0019901	protein kinase binding
0.34	GO:0003677	DNA binding
0.34	GO:0004170	dUTP diphosphatase activity
0.33	GO:0016301	kinase activity
0.33	GO:0004803	transposase activity
0.33	GO:0008270	zinc ion binding

0.35	GO:0005654	nucleoplasm
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.34	EC:3.6.1.23	GO:0004170
0.34	KEGG:R02100	GO:0004170

tr|T1G6X1|T1G6X1_HELRO
Uncharacterized protein
Search

tr|T1G6X2|T1G6X2_HELRO
Uncharacterized protein
Search

0.72	Transmembrane GTPase Marf

0.85	GO:0008053	mitochondrial fusion
0.47	GO:0048662	negative regulation of smooth muscle cell proliferation
0.42	GO:0051646	mitochondrion localization
0.38	GO:0098930	axonal transport
0.37	GO:0072384	organelle transport along microtubule
0.37	GO:0032990	cell part morphogenesis
0.36	GO:0007528	neuromuscular junction development
0.36	GO:0097193	intrinsic apoptotic signaling pathway
0.36	GO:0061564	axon development
0.36	GO:0030097	hemopoiesis

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005515	protein binding
0.33	GO:0008270	zinc ion binding
0.32	GO:0003676	nucleic acid binding

0.78	GO:0005741	mitochondrial outer membrane
0.41	GO:0098573	intrinsic component of mitochondrial membrane
0.37	GO:1904115	axon cytoplasm
0.34	GO:0031301	integral component of organelle membrane
0.34	GO:0098798	mitochondrial protein complex
0.33	GO:0098796	membrane protein complex
0.33	GO:0005634	nucleus

tr|T1G6X3|T1G6X3_HELRO
Uncharacterized protein
Search

0.61	lateral signaling target protein 2 homolog

0.41	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity
0.33	GO:0046854	phosphatidylinositol phosphorylation

0.52	GO:0046872	metal ion binding
0.40	GO:0032266	phosphatidylinositol-3-phosphate binding
0.34	GO:0000285	1-phosphatidylinositol-3-phosphate 5-kinase activity
0.33	GO:0046983	protein dimerization activity

0.40	GO:0031901	early endosome membrane
0.37	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.34	EC:2.7.1.150	GO:0000285
0.34	KEGG:R05802	GO:0000285

tr|T1G6X4|T1G6X4_HELRO
Uncharacterized protein
Search

0.67	Slingshot protein phosphatase 3

0.75	GO:0035335	peptidyl-tyrosine dephosphorylation
0.51	GO:0030036	actin cytoskeleton organization
0.47	GO:0010591	regulation of lamellipodium assembly
0.45	GO:0050770	regulation of axonogenesis
0.44	GO:0008064	regulation of actin polymerization or depolymerization
0.37	GO:0030335	positive regulation of cell migration

0.79	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.75	GO:0004725	protein tyrosine phosphatase activity
0.43	GO:0003779	actin binding
0.34	GO:0046983	protein dimerization activity

0.36	GO:0005737	cytoplasm
0.35	GO:0005615	extracellular space
0.35	GO:0005856	cytoskeleton
0.34	GO:0005925	focal adhesion
0.30	GO:0016020	membrane

0.79

GO:0008138

tr|T1G6X5|T1G6X5_HELRO
Uncharacterized protein
Search

0.91	REPO-paired class homeobox protein (Fragment)

0.59	GO:0007275	multicellular organism development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.46	GO:0006366	transcription by RNA polymerase II
0.44	GO:1902680	positive regulation of RNA biosynthetic process
0.43	GO:0060322	head development
0.43	GO:0009653	anatomical structure morphogenesis
0.41	GO:0048589	developmental growth
0.40	GO:0030154	cell differentiation

0.64	GO:0043565	sequence-specific DNA binding
0.46	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.45	GO:0001012	RNA polymerase II regulatory region DNA binding
0.44	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.43	GO:0003690	double-stranded DNA binding
0.40	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding
0.39	GO:0035326	enhancer binding
0.39	GO:0008013	beta-catenin binding
0.39	GO:0008022	protein C-terminus binding
0.38	GO:0003682	chromatin binding

0.61	GO:0005634	nucleus
0.37	GO:0005667	transcription factor complex
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.31

GO:0016491

tr|T1G6X6|T1G6X6_HELRO
Uncharacterized protein
Search

PEPCK

0.45	Phosphoenolpyruvate carboxykinase GTP

0.73	GO:0019319	hexose biosynthetic process
0.71	GO:0006006	glucose metabolic process
0.49	GO:0016310	phosphorylation
0.39	GO:0009749	response to glucose
0.37	GO:0048878	chemical homeostasis
0.35	GO:0006116	NADH oxidation
0.35	GO:0071548	response to dexamethasone
0.34	GO:0032024	positive regulation of insulin secretion
0.34	GO:0071331	cellular response to hexose stimulus
0.34	GO:0071356	cellular response to tumor necrosis factor

0.83	GO:0004613	phosphoenolpyruvate carboxykinase (GTP) activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0016301	kinase activity
0.33	GO:0046872	metal ion binding

0.38	GO:0055120	striated muscle dense body
0.35	GO:0005739	mitochondrion
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.83

EC:4.1.1.32

GO:0004613

tr|T1G6X7|T1G6X7_HELRO
Uncharacterized protein
Search

0.64	Smoothelin

0.44	GO:0051301	cell division
0.44	GO:0007049	cell cycle
0.43	GO:0009966	regulation of signal transduction
0.42	GO:0043547	positive regulation of GTPase activity
0.42	GO:0035335	peptidyl-tyrosine dephosphorylation
0.41	GO:0060325	face morphogenesis
0.39	GO:0007165	signal transduction
0.39	GO:0006468	protein phosphorylation
0.35	GO:1903506	regulation of nucleic acid-templated transcription
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.49	GO:0004386	helicase activity
0.49	GO:0003779	actin binding
0.43	GO:0030554	adenyl nucleotide binding
0.43	GO:0005509	calcium ion binding
0.43	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.43	GO:0032555	purine ribonucleotide binding
0.43	GO:0008144	drug binding
0.43	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0005096	GTPase activator activity
0.42	GO:0004725	protein tyrosine phosphatase activity

0.50	GO:0005921	gap junction
0.48	GO:0005819	spindle
0.40	GO:0005739	mitochondrion
0.34	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.42

GO:0004725

tr|T1G6X8|T1G6X8_HELRO
Uncharacterized protein
Search

tr|T1G6X9|T1G6X9_HELRO
Uncharacterized protein
Search

TRAPPC3

0.76	Trafficking protein particle complex subunit

0.74	GO:0048193	Golgi vesicle transport
0.46	GO:0046907	intracellular transport
0.42	GO:0016236	macroautophagy
0.41	GO:0033227	dsRNA transport
0.39	GO:0065009	regulation of molecular function
0.39	GO:0032258	protein localization by the Cvt pathway
0.34	GO:0006901	vesicle coating
0.34	GO:0006903	vesicle targeting
0.33	GO:0042338	cuticle development involved in collagen and cuticulin-based cuticle molting cycle
0.33	GO:0035264	multicellular organism growth

0.43

GO:0017112

Rab guanyl-nucleotide exchange factor activity

0.79	GO:0030008	TRAPP complex
0.66	GO:0005794	Golgi apparatus
0.65	GO:0005783	endoplasmic reticulum
0.47	GO:0098588	bounding membrane of organelle
0.44	GO:0005829	cytosol
0.43	GO:0031984	organelle subcompartment
0.42	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.42	GO:0005801	cis-Golgi network
0.41	GO:0044440	endosomal part
0.30	GO:0016021	integral component of membrane

tr|T1G6Y0|T1G6Y0_HELRO
Uncharacterized protein
Search

0.56	GO:0007283	spermatogenesis
0.48	GO:0055070	copper ion homeostasis
0.45	GO:0006511	ubiquitin-dependent protein catabolic process

0.47	GO:0070003	threonine-type peptidase activity
0.42	GO:0004175	endopeptidase activity
0.38	GO:0046872	metal ion binding

0.48	GO:0019773	proteasome core complex, alpha-subunit complex
0.41	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1G6Y1|T1G6Y1_HELRO
Uncharacterized protein
Search

tr|T1G6Y2|T1G6Y2_HELRO
Uncharacterized protein
Search

MMGT1

0.43	Membrane magnesium transporter

0.41	GO:0098655	cation transmembrane transport
0.40	GO:0015693	magnesium ion transport
0.37	GO:0006824	cobalt ion transport
0.37	GO:0006825	copper ion transport
0.37	GO:0098660	inorganic ion transmembrane transport
0.36	GO:0015684	ferrous iron transport
0.34	GO:0006828	manganese ion transport
0.34	GO:0072383	plus-end-directed vesicle transport along microtubule
0.34	GO:0044837	actomyosin contractile ring organization
0.34	GO:0000912	assembly of actomyosin apparatus involved in cytokinesis

0.41	GO:0022890	inorganic cation transmembrane transporter activity
0.33	GO:0016740	transferase activity
0.33	GO:0003777	microtubule motor activity
0.33	GO:0008017	microtubule binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.53	GO:0072546	ER membrane protein complex
0.47	GO:0005769	early endosome
0.44	GO:0005794	Golgi apparatus
0.39	GO:0010008	endosome membrane
0.38	GO:0005886	plasma membrane

0.33

GO:0016740

tr|T1G6Y3|T1G6Y3_HELRO
Uncharacterized protein
Search

0.66	GO:0043547	positive regulation of GTPase activity
0.51	GO:0006892	post-Golgi vesicle-mediated transport
0.47	GO:0035845	photoreceptor cell outer segment organization
0.46	GO:0010842	retina layer formation
0.46	GO:0048793	pronephros development
0.46	GO:0045494	photoreceptor cell maintenance
0.45	GO:0001947	heart looping
0.38	GO:0007023	post-chaperonin tubulin folding pathway
0.35	GO:0006629	lipid metabolic process
0.34	GO:0015031	protein transport

0.67	GO:0005096	GTPase activator activity
0.64	GO:0032550	purine ribonucleoside binding
0.64	GO:0019001	guanyl nucleotide binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0008081	phosphoric diester hydrolase activity
0.34	GO:0051082	unfolded protein binding

0.56	GO:1990075	periciliary membrane compartment
0.52	GO:0036064	ciliary basal body
0.52	GO:0005814	centriole
0.50	GO:0016604	nuclear body
0.48	GO:0031410	cytoplasmic vesicle
0.47	GO:0005794	Golgi apparatus
0.34	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.36

EC:3.1.4

GO:0008081

tr|T1G6Y4|T1G6Y4_HELRO
Uncharacterized protein
Search

RAB21

0.86	Putative rab subfamily protein of small gtpase

0.52	GO:0030100	regulation of endocytosis
0.52	GO:2000643	positive regulation of early endosome to late endosome transport
0.51	GO:0050775	positive regulation of dendrite morphogenesis
0.49	GO:0017157	regulation of exocytosis
0.40	GO:0008089	anterograde axonal transport
0.39	GO:0030516	regulation of axon extension
0.37	GO:0015031	protein transport
0.33	GO:0000413	protein peptidyl-prolyl isomerization
0.33	GO:0006457	protein folding
0.33	GO:0043547	positive regulation of GTPase activity

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0004767	sphingomyelin phosphodiesterase activity
0.34	GO:0005515	protein binding
0.33	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.33	GO:0005096	GTPase activator activity

0.53	GO:0098559	cytoplasmic side of early endosome membrane
0.48	GO:0032580	Golgi cisterna membrane
0.48	GO:0005802	trans-Golgi network
0.47	GO:0012506	vesicle membrane
0.47	GO:0043005	neuron projection
0.47	GO:0009898	cytoplasmic side of plasma membrane
0.39	GO:0032154	cleavage furrow
0.39	GO:0032838	plasma membrane bounded cell projection cytoplasm
0.37	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0005925	focal adhesion

0.34	EC:3.1.4.12	GO:0004767
0.34	KEGG:R02541	GO:0004767

tr|T1G6Y5|T1G6Y5_HELRO
Uncharacterized protein
Search

0.84	Ubiquitin carboxyl-terminal hydrolase 2

0.76	GO:0016579	protein deubiquitination
0.72	GO:0006511	ubiquitin-dependent protein catabolic process
0.49	GO:0043153	entrainment of circadian clock by photoperiod
0.49	GO:0045475	locomotor rhythm
0.49	GO:0050821	protein stabilization
0.48	GO:0032922	circadian regulation of gene expression
0.47	GO:0045931	positive regulation of mitotic cell cycle
0.46	GO:0000122	negative regulation of transcription by RNA polymerase II
0.42	GO:0048642	negative regulation of skeletal muscle tissue development
0.42	GO:1900037	regulation of cellular response to hypoxia

0.77	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.49	GO:0031625	ubiquitin protein ligase binding
0.47	GO:0030332	cyclin binding
0.44	GO:0042802	identical protein binding
0.41	GO:0051879	Hsp90 protein binding
0.41	GO:1990380	Lys48-specific deubiquitinase activity
0.34	GO:0046872	metal ion binding
0.33	GO:0004197	cysteine-type endopeptidase activity
0.32	GO:0015078	hydrogen ion transmembrane transporter activity
0.31	GO:0003676	nucleic acid binding

0.46	GO:0048471	perinuclear region of cytoplasm
0.45	GO:0005938	cell cortex
0.41	GO:0005634	nucleus
0.38	GO:0005789	endoplasmic reticulum membrane
0.38	GO:0005829	cytosol
0.35	GO:0005813	centrosome
0.33	GO:0033179	proton-transporting V-type ATPase, V0 domain
0.33	GO:0043233	organelle lumen
0.30	GO:0031224	intrinsic component of membrane

0.77

GO:0036459

tr|T1G6Y6|T1G6Y6_HELRO
Phosphoinositide phospholipase C
Search

PLCG1

0.52	Phosphoinositide phospholipase C

0.72	GO:0009395	phospholipid catabolic process
0.63	GO:0035556	intracellular signal transduction
0.52	GO:0071364	cellular response to epidermal growth factor stimulus
0.52	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol
0.52	GO:0050852	T cell receptor signaling pathway
0.52	GO:0043536	positive regulation of blood vessel endothelial cell migration
0.52	GO:0007173	epidermal growth factor receptor signaling pathway
0.51	GO:0045766	positive regulation of angiogenesis
0.48	GO:0016477	cell migration
0.47	GO:0001701	in utero embryonic development

0.82	GO:0004435	phosphatidylinositol phospholipase C activity
0.62	GO:0004871	signal transducer activity
0.62	GO:0005509	calcium ion binding
0.54	GO:0005168	neurotrophin TRKA receptor binding
0.53	GO:0035254	glutamate receptor binding
0.51	GO:0030971	receptor tyrosine kinase binding
0.35	GO:0001784	phosphotyrosine residue binding
0.33	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors
0.33	GO:0003777	microtubule motor activity
0.33	GO:0008017	microtubule binding

0.50	GO:0001726	ruffle
0.50	GO:0030027	lamellipodium
0.50	GO:0008180	COP9 signalosome
0.48	GO:0005911	cell-cell junction
0.45	GO:0005829	cytosol
0.40	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.82	EC:3.1.4.11	GO:0004435
0.82	KEGG:R03435	GO:0004435

tr|T1G6Y7|T1G6Y7_HELRO
Kinase
Search

0.55

Kinase

0.83	GO:0032958	inositol phosphate biosynthetic process
0.57	GO:0016310	phosphorylation
0.43	GO:0048815	hermaphrodite genitalia morphogenesis

0.60	GO:0016301	kinase activity
0.33	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0046872	metal ion binding
0.32	GO:0032553	ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003676	nucleic acid binding
0.32	GO:0016787	hydrolase activity

0.30

GO:0031224

intrinsic component of membrane

0.33

GO:0016773

tr|T1G6Y8|T1G6Y8_HELRO
Synaptotagmin 7b
Search

SYT7

0.86	Synaptotagmin VIIa

0.76	GO:0006887	exocytosis
0.54	GO:0099643	signal release from synapse
0.54	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.53	GO:0090119	vesicle-mediated cholesterol transport
0.52	GO:1990926	short-term synaptic potentiation
0.52	GO:0017158	regulation of calcium ion-dependent exocytosis
0.52	GO:0070092	regulation of glucagon secretion
0.51	GO:0090385	phagosome-lysosome fusion
0.51	GO:0048489	synaptic vesicle transport
0.51	GO:0099504	synaptic vesicle cycle

0.81	GO:0005544	calcium-dependent phospholipid binding
0.51	GO:0000149	SNARE binding
0.50	GO:0001786	phosphatidylserine binding
0.49	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.47	GO:0005516	calmodulin binding
0.45	GO:0030276	clathrin binding
0.42	GO:0005509	calcium ion binding

0.52	GO:0098793	presynapse
0.51	GO:0032009	early phagosome
0.49	GO:0070382	exocytic vesicle
0.49	GO:0044306	neuron projection terminus
0.48	GO:0043025	neuronal cell body
0.47	GO:0030425	dendrite
0.47	GO:0097060	synaptic membrane
0.47	GO:0005764	lysosome
0.46	GO:0005777	peroxisome
0.43	GO:0005829	cytosol

tr|T1G6Y9|T1G6Y9_HELRO
Uncharacterized protein
Search

0.44	Restna and anterior neural fold homeobox protein, putative

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.54	GO:0048856	anatomical structure development
0.52	GO:0032501	multicellular organismal process
0.42	GO:2000179	positive regulation of neural precursor cell proliferation
0.37	GO:0007610	behavior
0.37	GO:0030334	regulation of cell migration
0.37	GO:0016477	cell migration
0.37	GO:1902679	negative regulation of RNA biosynthetic process

0.63	GO:0043565	sequence-specific DNA binding
0.36	GO:0003700	DNA binding transcription factor activity
0.34	GO:0004000	adenosine deaminase activity
0.33	GO:0008061	chitin binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.34

GO:0004000

tr|T1G6Z0|T1G6Z0_HELRO
Uncharacterized protein
Search

LYAR

0.63	Cell growth-regulating nucleolar protein (Fragment)

0.83	GO:0048821	erythrocyte development
0.82	GO:0050766	positive regulation of phagocytosis
0.75	GO:0000122	negative regulation of transcription by RNA polymerase II
0.66	GO:0006364	rRNA processing
0.37	GO:0006468	protein phosphorylation

0.53	GO:0003677	DNA binding
0.39	GO:0004674	protein serine/threonine kinase activity
0.38	GO:0046872	metal ion binding
0.38	GO:0003723	RNA binding
0.36	GO:0005515	protein binding
0.36	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.80	GO:0001750	photoreceptor outer segment
0.70	GO:0005730	nucleolus

0.39

GO:0004674

tr|T1G6Z1|T1G6Z1_HELRO
Uncharacterized protein
Search

FXR1

0.68	Fragile X mental retardation protein 1

0.48	GO:0007517	muscle organ development
0.46	GO:2000637	positive regulation of gene silencing by miRNA
0.44	GO:0017148	negative regulation of translation
0.43	GO:0001756	somitogenesis
0.43	GO:0048747	muscle fiber development
0.42	GO:0014706	striated muscle tissue development
0.42	GO:0007507	heart development
0.34	GO:0097091	synaptic vesicle clustering
0.34	GO:0070142	synaptic vesicle budding
0.34	GO:0090328	regulation of olfactory learning

0.59	GO:0003723	RNA binding
0.45	GO:0097617	annealing activity
0.43	GO:0042803	protein homodimerization activity
0.42	GO:0046982	protein heterodimerization activity
0.34	GO:0043621	protein self-association
0.33	GO:0045182	translation regulator activity
0.33	GO:0004674	protein serine/threonine kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding

0.46	GO:0005844	polysome
0.45	GO:0043034	costamere
0.44	GO:0043197	dendritic spine
0.43	GO:0030424	axon
0.43	GO:0035770	ribonucleoprotein granule
0.42	GO:0048471	perinuclear region of cytoplasm
0.41	GO:0005829	cytosol
0.40	GO:0005634	nucleus
0.34	GO:0035068	micro-ribonucleoprotein complex
0.34	GO:0060293	germ plasm

0.33

GO:0004674

tr|T1G6Z2|T1G6Z2_HELRO
Uncharacterized protein
Search

MRRF

0.70	Mitochondrial ribosome recycling factor

0.60	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.54	GO:0032790	ribosome disassembly
0.54	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.36	GO:0019371	cyclooxygenase pathway
0.36	GO:0008217	regulation of blood pressure
0.35	GO:0006954	inflammatory response
0.34	GO:0006979	response to oxidative stress
0.34	GO:0098869	cellular oxidant detoxification

0.46	GO:0043023	ribosomal large subunit binding
0.36	GO:0004666	prostaglandin-endoperoxide synthase activity
0.35	GO:0004601	peroxidase activity
0.34	GO:0020037	heme binding

0.45

GO:0005739

mitochondrion

0.36	EC:1.14.99.1	GO:0004666
0.35	KEGG:R03532	GO:0004601

tr|T1G6Z3|T1G6Z3_HELRO
Uncharacterized protein
Search

CTSZ

0.91	Cathepsin Z

0.61	GO:0006508	proteolysis
0.53	GO:0010757	negative regulation of plasminogen activation
0.52	GO:0060441	epithelial tube branching involved in lung morphogenesis
0.50	GO:0032091	negative regulation of protein binding
0.49	GO:1901214	regulation of neuron death
0.43	GO:0001525	angiogenesis
0.43	GO:0044257	cellular protein catabolic process
0.38	GO:2000179	positive regulation of neural precursor cell proliferation
0.37	GO:0010977	negative regulation of neuron projection development
0.36	GO:0043065	positive regulation of apoptotic process

0.72	GO:0008234	cysteine-type peptidase activity
0.46	GO:0004180	carboxypeptidase activity
0.41	GO:0004175	endopeptidase activity

0.51	GO:0005764	lysosome
0.50	GO:0099738	cell cortex region
0.49	GO:0005615	extracellular space
0.46	GO:0031410	cytoplasmic vesicle
0.45	GO:0005783	endoplasmic reticulum
0.37	GO:0030426	growth cone
0.36	GO:0009986	cell surface
0.34	GO:1903561	extracellular vesicle
0.30	GO:0016020	membrane

0.72

GO:0008234

tr|T1G6Z4|T1G6Z4_HELRO
Uncharacterized protein
Search

0.55	GO:0055085	transmembrane transport
0.36	GO:0006811	ion transport

0.36

GO:0005215

transporter activity

0.38	GO:0005794	Golgi apparatus
0.30	GO:0016020	membrane

tr|T1G6Z5|T1G6Z5_HELRO
Uncharacterized protein
Search

0.54	Transmembrane protein 138 (inferred by orthology to a human protein)

0.30

GO:0044425

membrane part

tr|T1G6Z6|T1G6Z6_HELRO
Uncharacterized protein
Search

DFD

0.47	Transcription factor Deformed (Fragment)

0.65	GO:0007275	multicellular organism development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0048863	stem cell differentiation
0.51	GO:1902680	positive regulation of RNA biosynthetic process
0.50	GO:0009653	anatomical structure morphogenesis
0.49	GO:0006366	transcription by RNA polymerase II
0.45	GO:2000738	positive regulation of stem cell differentiation
0.45	GO:0048103	somatic stem cell division

0.65	GO:0043565	sequence-specific DNA binding
0.58	GO:0003700	DNA binding transcription factor activity
0.50	GO:0001012	RNA polymerase II regulatory region DNA binding
0.47	GO:0003690	double-stranded DNA binding
0.35	GO:0035326	enhancer binding
0.34	GO:0071837	HMG box domain binding

0.61	GO:0005634	nucleus
0.48	GO:0030054	cell junction
0.45	GO:0031974	membrane-enclosed lumen
0.43	GO:0044446	intracellular organelle part
0.41	GO:0015630	microtubule cytoskeleton
0.33	GO:0005829	cytosol

tr|T1G6Z7|T1G6Z7_HELRO
Guanylate cyclase
Search

0.40	Guanylate cyclase

0.82	GO:0006182	cGMP biosynthetic process
0.63	GO:0035556	intracellular signal transduction
0.59	GO:0006468	protein phosphorylation
0.44	GO:0045792	negative regulation of cell size
0.42	GO:0007030	Golgi organization
0.42	GO:0045931	positive regulation of mitotic cell cycle
0.42	GO:0008284	positive regulation of cell proliferation
0.36	GO:0007168	receptor guanylyl cyclase signaling pathway
0.35	GO:0007631	feeding behavior
0.35	GO:0009628	response to abiotic stimulus

0.82	GO:0004383	guanylate cyclase activity
0.60	GO:0004672	protein kinase activity
0.53	GO:1901265	nucleoside phosphate binding
0.51	GO:0036094	small molecule binding
0.51	GO:0008144	drug binding
0.51	GO:0097367	carbohydrate derivative binding
0.50	GO:0043168	anion binding
0.44	GO:0020037	heme binding
0.44	GO:0004016	adenylate cyclase activity
0.37	GO:0004872	receptor activity

0.46	GO:0008074	guanylate cyclase complex, soluble
0.38	GO:0005886	plasma membrane
0.36	GO:0043025	neuronal cell body
0.36	GO:0030425	dendrite
0.34	GO:0097730	non-motile cilium
0.34	GO:0043235	receptor complex
0.30	GO:0016021	integral component of membrane

0.82

GO:0004383

tr|T1G6Z8|T1G6Z8_HELRO
Mothers against decapentaplegic homolog
Search

SMAD4

0.63	Mothers against decapentaplegic homolog

0.83	GO:0007179	transforming growth factor beta receptor signaling pathway
0.61	GO:0003251	positive regulation of cell proliferation involved in heart valve morphogenesis
0.61	GO:1905305	negative regulation of cardiac myofibril assembly
0.60	GO:0061040	female gonad morphogenesis
0.60	GO:0003220	left ventricular cardiac muscle tissue morphogenesis
0.60	GO:0072134	nephrogenic mesenchyme morphogenesis
0.60	GO:0046881	positive regulation of follicle-stimulating hormone secretion
0.60	GO:0033686	positive regulation of luteinizing hormone secretion
0.60	GO:0072133	metanephric mesenchyme morphogenesis
0.59	GO:0003360	brainstem development

0.61	GO:0003700	DNA binding transcription factor activity
0.60	GO:0030616	transforming growth factor beta receptor, common-partner cytoplasmic mediator activity
0.59	GO:0043199	sulfate binding
0.58	GO:0070411	I-SMAD binding
0.57	GO:0070412	R-SMAD binding
0.55	GO:0001085	RNA polymerase II transcription factor binding
0.55	GO:0005518	collagen binding
0.54	GO:0003677	DNA binding
0.52	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.52	GO:0003682	chromatin binding

0.75	GO:0005667	transcription factor complex
0.61	GO:0005634	nucleus
0.58	GO:0071141	SMAD protein complex
0.52	GO:0005813	centrosome
0.49	GO:0000785	chromatin
0.48	GO:0005737	cytoplasm
0.47	GO:0070013	intracellular organelle lumen
0.30	GO:0031224	intrinsic component of membrane

tr|T1G6Z9|T1G6Z9_HELRO
Uncharacterized protein
Search

0.61	GO:0006508	proteolysis
0.43	GO:0042060	wound healing
0.42	GO:0032101	regulation of response to external stimulus
0.41	GO:0031347	regulation of defense response
0.40	GO:0048193	Golgi vesicle transport
0.40	GO:0048585	negative regulation of response to stimulus
0.40	GO:1902741	positive regulation of interferon-alpha secretion
0.39	GO:0001961	positive regulation of cytokine-mediated signaling pathway
0.39	GO:0090504	epiboly
0.39	GO:0002831	regulation of response to biotic stimulus

0.70	GO:0004222	metalloendopeptidase activity
0.63	GO:0008270	zinc ion binding
0.38	GO:0005518	collagen binding
0.38	GO:0001047	core promoter binding
0.37	GO:0005509	calcium ion binding
0.36	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.36	GO:0043565	sequence-specific DNA binding
0.34	GO:0004984	olfactory receptor activity
0.34	GO:0004930	G-protein coupled receptor activity
0.33	GO:0004252	serine-type endopeptidase activity

0.74	GO:0031012	extracellular matrix
0.42	GO:0030008	TRAPP complex
0.37	GO:0005615	extracellular space
0.35	GO:0005634	nucleus
0.33	GO:0005581	collagen trimer
0.33	GO:0005737	cytoplasm
0.32	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

0.70

GO:0004222

tr|T1G700|T1G700_HELRO
Uncharacterized protein
Search

0.57	GO:0051014	actin filament severing
0.55	GO:0007527	adult somatic muscle development
0.54	GO:0001703	gastrulation with mouth forming first
0.52	GO:0030239	myofibril assembly
0.47	GO:0006468	protein phosphorylation
0.39	GO:0006470	protein dephosphorylation
0.39	GO:0007165	signal transduction
0.38	GO:0045087	innate immune response
0.36	GO:0042116	macrophage activation
0.36	GO:0071222	cellular response to lipopolysaccharide

0.54	GO:0051015	actin filament binding
0.48	GO:0004672	protein kinase activity
0.43	GO:0097367	carbohydrate derivative binding
0.43	GO:0030554	adenyl nucleotide binding
0.43	GO:0008144	drug binding
0.42	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0004721	phosphoprotein phosphatase activity
0.37	GO:0004888	transmembrane signaling receptor activity
0.37	GO:0001875	lipopolysaccharide receptor activity
0.36	GO:0005509	calcium ion binding

0.37	GO:0046696	lipopolysaccharide receptor complex
0.34	GO:0005576	extracellular region
0.33	GO:0005886	plasma membrane
0.32	GO:0005737	cytoplasm

0.39

EC:3.1.3.16

GO:0004721

tr|T1G701|T1G701_HELRO
Uncharacterized protein
Search

SIX2

0.86	SIX class homeodomain transcription factor

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0048513	animal organ development
0.54	GO:0008283	cell proliferation
0.50	GO:1902732	positive regulation of chondrocyte proliferation
0.50	GO:0016477	cell migration
0.49	GO:0007501	mesodermal cell fate specification
0.49	GO:0090189	regulation of branching involved in ureteric bud morphogenesis
0.49	GO:0060231	mesenchymal to epithelial transition

0.65	GO:0043565	sequence-specific DNA binding
0.48	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.47	GO:0008134	transcription factor binding
0.45	GO:0001012	RNA polymerase II regulatory region DNA binding
0.44	GO:0032403	protein complex binding
0.44	GO:0003690	double-stranded DNA binding
0.34	GO:0003682	chromatin binding

0.61	GO:0005634	nucleus
0.34	GO:0005667	transcription factor complex
0.33	GO:0043233	organelle lumen
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.32	GO:0044446	intracellular organelle part
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|T1G702|T1G702_HELRO
Uncharacterized protein
Search

tr|T1G703|T1G703_HELRO
Uncharacterized protein
Search

0.47	Homeobox protein abdominal-A homolog (Fragment)

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0007275	multicellular organism development
0.34	GO:0006351	transcription, DNA-templated

0.64	GO:0043565	sequence-specific DNA binding
0.50	GO:0003700	DNA binding transcription factor activity
0.34	GO:0003950	NAD+ ADP-ribosyltransferase activity

0.61	GO:0005634	nucleus
0.36	GO:0030054	cell junction
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0044446	intracellular organelle part

0.34

GO:0003950

tr|T1G704|T1G704_HELRO
Uncharacterized protein
Search

DNAI2

0.78	Axonemal outer arm dynein intermediate chain 1

0.85	GO:0036158	outer dynein arm assembly
0.70	GO:0003341	cilium movement
0.68	GO:0046692	sperm competition
0.66	GO:0010996	response to auditory stimulus
0.62	GO:0007605	sensory perception of sound
0.55	GO:0007368	determination of left/right symmetry
0.38	GO:1902476	chloride transmembrane transport
0.36	GO:0007186	G-protein coupled receptor signaling pathway

0.69	GO:0045504	dynein heavy chain binding
0.68	GO:0045503	dynein light chain binding
0.67	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed
0.38	GO:0005254	chloride channel activity
0.36	GO:0004930	G-protein coupled receptor activity

0.74	GO:0036157	outer dynein arm
0.61	GO:0043025	neuronal cell body
0.61	GO:0030425	dendrite
0.56	GO:0036126	sperm flagellum
0.55	GO:0009897	external side of plasma membrane
0.42	GO:0005874	microtubule
0.38	GO:0034707	chloride channel complex

0.67

EC:3.6.4.4

GO:0008574

tr|T1G705|T1G705_HELRO
Uncharacterized protein
Search

MRPL51

0.71	Large subunit ribosomal protein L51

0.37	GO:0006412	translation
0.35	GO:0140053	mitochondrial gene expression

0.64	GO:0003735	structural constituent of ribosome
0.34	GO:0008270	zinc ion binding

0.52	GO:0005840	ribosome
0.40	GO:0005759	mitochondrial matrix

tr|T1G706|T1G706_HELRO
Uncharacterized protein
Search

GGACT

0.72	Gamma-glutamylamine cyclotransferase

0.60

GO:0042219

cellular modified amino acid catabolic process

0.64	GO:0003839	gamma-glutamylcyclotransferase activity
0.40	GO:0016829	lyase activity
0.36	GO:0005515	protein binding
0.35	GO:0008270	zinc ion binding

0.43	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.64

EC:2.3.2.4

GO:0003839

tr|T1G707|T1G707_HELRO
Uncharacterized protein
Search

ABCG2

0.89	Placenta-specific ATP-binding cassette transporter

0.49	GO:0046415	urate metabolic process
0.49	GO:0033344	cholesterol efflux
0.49	GO:0055085	transmembrane transport
0.43	GO:0015893	drug transport
0.37	GO:0097744	urate salt excretion
0.37	GO:1904612	response to 2,3,7,8-tetrachlorodibenzodioxine
0.37	GO:0019389	glucuronoside metabolic process
0.37	GO:1904479	negative regulation of intestinal absorption
0.36	GO:0060136	embryonic process involved in female pregnancy
0.36	GO:0051593	response to folic acid

0.61	GO:0016887	ATPase activity
0.57	GO:0015399	primary active transmembrane transporter activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0017127	cholesterol transporter activity
0.45	GO:0042803	protein homodimerization activity
0.36	GO:0042910	xenobiotic transmembrane transporter activity
0.36	GO:0015238	drug transmembrane transporter activity
0.34	GO:0008092	cytoskeletal protein binding

0.47	GO:0016324	apical plasma membrane
0.46	GO:0043235	receptor complex
0.41	GO:0005634	nucleus
0.36	GO:0031966	mitochondrial membrane
0.35	GO:0043190	ATP-binding cassette (ABC) transporter complex

0.61

GO:0016887

tr|T1G708|T1G708_HELRO
Uncharacterized protein
Search

0.76	Vitamin K epoxide reductase complex subunit 1 protein 1

0.30

GO:0044425

membrane part

tr|T1G709|T1G709_HELRO
Uncharacterized protein
Search

0.38	Zinc finger domain containing protein

0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression
0.34	GO:0031018	endocrine pancreas development
0.33	GO:1902679	negative regulation of RNA biosynthetic process
0.33	GO:0006493	protein O-linked glycosylation
0.33	GO:0097502	mannosylation
0.32	GO:0006351	transcription, DNA-templated

0.51	GO:0003676	nucleic acid binding
0.34	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.34	GO:0046872	metal ion binding
0.33	GO:0000030	mannosyltransferase activity

0.34	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.33

GO:0000030

tr|T1G710|T1G710_HELRO
Uncharacterized protein
Search

tr|T1G711|T1G711_HELRO
Uncharacterized protein
Search

CMIP

0.96	C-Maf-inducing protein isoform C-Mip

0.38	GO:0016042	lipid catabolic process
0.36	GO:0035556	intracellular signal transduction

0.39	GO:0004435	phosphatidylinositol phospholipase C activity
0.37	GO:0005515	protein binding
0.36	GO:0004871	signal transducer activity

0.69	GO:0005654	nucleoplasm
0.67	GO:0005829	cytosol

0.39	EC:3.1.4.11	GO:0004435
0.39	KEGG:R03435	GO:0004435

tr|T1G712|T1G712_HELRO
Uncharacterized protein
Search

SPNS1

0.80	Vesicular glutamate transporter 2

0.55	GO:0055085	transmembrane transport
0.41	GO:0003376	sphingosine-1-phosphate signaling pathway
0.39	GO:0006869	lipid transport
0.37	GO:0040011	locomotion
0.37	GO:0008643	carbohydrate transport
0.35	GO:0035193	larval central nervous system remodeling
0.35	GO:0090099	negative regulation of decapentaplegic signaling pathway
0.35	GO:0045477	regulation of nurse cell apoptotic process
0.35	GO:0045476	nurse cell apoptotic process
0.35	GO:0090398	cellular senescence

0.42	GO:0046624	sphingolipid transporter activity
0.33	GO:0005515	protein binding
0.32	GO:0046872	metal ion binding

0.40	GO:0005765	lysosomal membrane
0.38	GO:0031982	vesicle
0.34	GO:0031966	mitochondrial membrane
0.34	GO:0019866	organelle inner membrane
0.34	GO:0045202	synapse
0.33	GO:0012505	endomembrane system
0.30	GO:0031224	intrinsic component of membrane

tr|T1G713|T1G713_HELRO
Uncharacterized protein
Search

0.10	Adenosine kinase

0.36	GO:0032504	multicellular organism reproduction
0.34	GO:0006468	protein phosphorylation
0.34	GO:0006414	translational elongation
0.33	GO:0007165	signal transduction
0.33	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.33	GO:0006754	ATP biosynthetic process
0.33	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.32	GO:0055114	oxidation-reduction process

0.35	GO:0016301	kinase activity
0.34	GO:0003746	translation elongation factor activity
0.34	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.34	GO:0140096	catalytic activity, acting on a protein
0.34	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0051213	dioxygenase activity

0.36	GO:0005615	extracellular space
0.30	GO:0016020	membrane

0.34

GO:0016773

tr|T1G714|T1G714_HELRO
Uncharacterized protein
Search

0.71	Potassium voltage-gated channel subfamily Q member 1

0.73	GO:0071805	potassium ion transmembrane transport
0.49	GO:0060453	regulation of gastric acid secretion
0.49	GO:0086009	membrane repolarization
0.48	GO:0070293	renal absorption
0.48	GO:0060372	regulation of atrial cardiac muscle cell membrane repolarization
0.47	GO:0060452	positive regulation of cardiac muscle contraction
0.47	GO:0086014	atrial cardiac muscle cell action potential
0.47	GO:0035690	cellular response to drug
0.47	GO:0086005	ventricular cardiac muscle cell action potential
0.47	GO:0010460	positive regulation of heart rate

0.78	GO:0005249	voltage-gated potassium channel activity
0.47	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.46	GO:0034236	protein kinase A catalytic subunit binding
0.46	GO:0034237	protein kinase A regulatory subunit binding
0.46	GO:0097110	scaffold protein binding
0.46	GO:0008157	protein phosphatase 1 binding
0.45	GO:0005516	calmodulin binding
0.45	GO:0044325	ion channel binding
0.33	GO:0042803	protein homodimerization activity

0.78	GO:0008076	voltage-gated potassium channel complex
0.46	GO:0016323	basolateral plasma membrane
0.46	GO:0098857	membrane microdomain
0.46	GO:0005769	early endosome
0.44	GO:0005770	late endosome
0.44	GO:0005764	lysosome
0.43	GO:0005783	endoplasmic reticulum
0.39	GO:0030659	cytoplasmic vesicle membrane
0.34	GO:0042588	zymogen granule
0.34	GO:0042383	sarcolemma

tr|T1G715|T1G715_HELRO
Uncharacterized protein
Search

ENOPH1

0.60	Acireductone synthase

0.77	GO:0019509	L-methionine salvage from methylthioadenosine
0.68	GO:0016311	dephosphorylation
0.67	GO:0019284	L-methionine salvage from S-adenosylmethionine
0.32	GO:0055114	oxidation-reduction process

0.84	GO:0043874	acireductone synthase activity
0.72	GO:0043716	2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase activity
0.72	GO:0043715	2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity
0.64	GO:0000287	magnesium ion binding
0.59	GO:0046570	methylthioribulose 1-phosphate dehydratase activity
0.47	GO:0008270	zinc ion binding
0.35	GO:0003677	DNA binding
0.33	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.33	GO:0020037	heme binding
0.33	GO:0005506	iron ion binding

0.49	GO:0005634	nucleus
0.46	GO:0005737	cytoplasm
0.32	GO:0044446	intracellular organelle part

0.84	EC:3.1.3.77	GO:0043874
0.72	KEGG:R07394	GO:0043716

tr|T1G716|T1G716_HELRO
Uncharacterized protein
Search

0.84	Interferon-inducible double stranded RNA-dependent protein kinase activator A-like A

0.85	GO:0030422	production of siRNA involved in RNA interference
0.74	GO:0031054	pre-miRNA processing
0.71	GO:0035280	miRNA loading onto RISC involved in gene silencing by miRNA
0.67	GO:0030423	targeting of mRNA for destruction involved in RNA interference
0.64	GO:0046782	regulation of viral transcription
0.61	GO:0043085	positive regulation of catalytic activity
0.51	GO:0050689	negative regulation of defense response to virus by host
0.50	GO:0035087	siRNA loading onto RISC involved in RNA interference
0.49	GO:0045070	positive regulation of viral genome replication
0.49	GO:0042473	outer ear morphogenesis

0.76	GO:0003725	double-stranded RNA binding
0.71	GO:0035197	siRNA binding
0.65	GO:0035198	miRNA binding
0.62	GO:0008047	enzyme activator activity
0.60	GO:0042803	protein homodimerization activity
0.54	GO:0070883	pre-miRNA binding
0.48	GO:0019899	enzyme binding
0.48	GO:0047485	protein N-terminus binding
0.42	GO:0016301	kinase activity
0.34	GO:0036002	pre-mRNA binding

0.68	GO:0016442	RISC complex
0.58	GO:0070578	RISC-loading complex
0.54	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0035068	micro-ribonucleoprotein complex
0.48	GO:0005654	nucleoplasm
0.42	GO:0005829	cytosol
0.33	GO:0005730	nucleolus
0.33	GO:0016589	NURF complex
0.33	GO:0034708	methyltransferase complex
0.30	GO:0016020	membrane

tr|T1G717|T1G717_HELRO
Uncharacterized protein
Search

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.52	GO:0046329	negative regulation of JNK cascade
0.48	GO:0043069	negative regulation of programmed cell death
0.46	GO:0051254	positive regulation of RNA metabolic process
0.46	GO:0051726	regulation of cell cycle
0.46	GO:0010557	positive regulation of macromolecule biosynthetic process
0.46	GO:0031328	positive regulation of cellular biosynthetic process
0.45	GO:0051253	negative regulation of RNA metabolic process

0.51	GO:0003676	nucleic acid binding
0.42	GO:0003700	DNA binding transcription factor activity
0.38	GO:0042803	protein homodimerization activity
0.35	GO:0018024	histone-lysine N-methyltransferase activity
0.34	GO:0046872	metal ion binding
0.33	GO:0016407	acetyltransferase activity
0.32	GO:0016301	kinase activity

0.51	GO:0016607	nuclear speck
0.50	GO:0000118	histone deacetylase complex
0.34	GO:0005829	cytosol

0.35

EC:2.1.1.43

GO:0018024

tr|T1G718|T1G718_HELRO
Uncharacterized protein
Search

DHCR24

0.92	24-dehydrocholesterol reductase

0.54	GO:0042987	amyloid precursor protein catabolic process
0.53	GO:0031639	plasminogen activation
0.53	GO:0006695	cholesterol biosynthetic process
0.53	GO:0030539	male genitalia development
0.52	GO:0055114	oxidation-reduction process
0.52	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.52	GO:0043588	skin development
0.49	GO:0009888	tissue development
0.47	GO:0006979	response to oxidative stress
0.45	GO:0061024	membrane organization

0.66	GO:0050660	flavin adenine dinucleotide binding
0.65	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors
0.58	GO:0000246	delta24(24-1) sterol reductase activity
0.54	GO:0042605	peptide antigen binding
0.47	GO:0019899	enzyme binding
0.40	GO:0050614	delta24-sterol reductase activity

0.46	GO:0005783	endoplasmic reticulum
0.43	GO:0005634	nucleus
0.37	GO:0000139	Golgi membrane
0.36	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0005856	cytoskeleton
0.35	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.65	EC:1.1	GO:0016614
0.58	KEGG:R05641	GO:0000246

tr|T1G719|T1G719_HELRO
Uncharacterized protein
Search

0.49	Low-density lipoprotein receptor-related protein 8

0.43	GO:0007160	cell-matrix adhesion
0.39	GO:0048513	animal organ development
0.38	GO:0072001	renal system development
0.38	GO:0010811	positive regulation of cell-substrate adhesion
0.37	GO:0030198	extracellular matrix organization
0.37	GO:0030509	BMP signaling pathway
0.36	GO:0060828	regulation of canonical Wnt signaling pathway
0.36	GO:0030334	regulation of cell migration
0.35	GO:0009790	embryo development
0.35	GO:0003002	regionalization

0.66	GO:0005509	calcium ion binding
0.39	GO:0043236	laminin binding
0.39	GO:0043394	proteoglycan binding
0.39	GO:0005518	collagen binding
0.35	GO:0030228	lipoprotein particle receptor activity
0.35	GO:0005102	receptor binding
0.34	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.34	GO:0003779	actin binding
0.33	GO:0001540	amyloid-beta binding
0.33	GO:1990782	protein tyrosine kinase binding

0.41	GO:0005794	Golgi apparatus
0.39	GO:0005605	basal lamina
0.36	GO:0005615	extracellular space
0.35	GO:0031410	cytoplasmic vesicle
0.35	GO:0043235	receptor complex
0.35	GO:0071944	cell periphery
0.34	GO:0098589	membrane region
0.34	GO:0005829	cytosol
0.34	GO:0009986	cell surface
0.33	GO:0031594	neuromuscular junction

0.34

GO:0003950

tr|T1G720|T1G720_HELRO
Uncharacterized protein
Search

0.51	GO:0016180	snRNA processing
0.38	GO:0043628	ncRNA 3'-end processing
0.36	GO:0031060	regulation of histone methylation
0.34	GO:0006950	response to stress
0.34	GO:0051716	cellular response to stimulus
0.34	GO:0042795	snRNA transcription by RNA polymerase II
0.34	GO:0008610	lipid biosynthetic process
0.33	GO:0007041	lysosomal transport
0.33	GO:0031057	negative regulation of histone modification
0.33	GO:0031058	positive regulation of histone modification

0.54	GO:0046872	metal ion binding
0.36	GO:0035064	methylated histone binding
0.36	GO:0008609	alkylglycerone-phosphate synthase activity
0.34	GO:0050660	flavin adenine dinucleotide binding
0.34	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors
0.34	GO:0030882	lipid antigen binding
0.34	GO:0070891	lipoteichoic acid binding
0.33	GO:0001530	lipopolysaccharide binding
0.33	GO:0051219	phosphoprotein binding
0.33	GO:0042834	peptidoglycan binding

0.49	GO:0032039	integrator complex
0.33	GO:0035098	ESC/E(Z) complex
0.33	GO:0035861	site of double-strand break
0.33	GO:0005615	extracellular space
0.33	GO:0005813	centrosome
0.30	GO:0031224	intrinsic component of membrane

0.36

EC:2.5.1.26

GO:0008609

tr|T1G721|T1G721_HELRO
Uncharacterized protein
Search

0.72	GO:0006325	chromatin organization
0.54	GO:0071824	protein-DNA complex subunit organization
0.52	GO:0006323	DNA packaging
0.49	GO:0034622	cellular macromolecular complex assembly
0.40	GO:0030216	keratinocyte differentiation
0.39	GO:0035039	male pronucleus assembly
0.39	GO:0007143	female meiotic nuclear division
0.35	GO:0043412	macromolecule modification

0.38	GO:0008134	transcription factor binding
0.36	GO:0003677	DNA binding

0.61	GO:0005634	nucleus
0.55	GO:0005923	bicellular tight junction
0.49	GO:0031974	membrane-enclosed lumen
0.44	GO:0044446	intracellular organelle part
0.37	GO:0000793	condensed chromosome
0.35	GO:0043234	protein complex

tr|T1G722|T1G722_HELRO
Uncharacterized protein
Search

0.91	Red protein ik factor cytokine ik

0.47	GO:0034501	protein localization to kinetochore
0.46	GO:0007094	mitotic spindle assembly checkpoint
0.40	GO:0060047	heart contraction
0.38	GO:0042273	ribosomal large subunit biogenesis
0.37	GO:0006396	RNA processing
0.37	GO:0016072	rRNA metabolic process
0.35	GO:0016071	mRNA metabolic process
0.34	GO:0006508	proteolysis
0.33	GO:0016032	viral process

0.43	GO:0042802	identical protein binding
0.35	GO:0004252	serine-type endopeptidase activity
0.34	GO:0051537	2 iron, 2 sulfur cluster binding

0.61	GO:0005634	nucleus
0.47	GO:0097431	mitotic spindle pole
0.41	GO:0005694	chromosome
0.41	GO:0031974	membrane-enclosed lumen
0.34	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.35

GO:0004252

tr|T1G723|T1G723_HELRO
Uncharacterized protein
Search

0.63	Neurotransmitter-gated ion-channel ligand binding domain protein

0.78	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.44	GO:0035094	response to nicotine
0.41	GO:0007271	synaptic transmission, cholinergic
0.40	GO:0050433	regulation of catecholamine secretion
0.39	GO:0051899	membrane depolarization
0.39	GO:0007274	neuromuscular synaptic transmission
0.39	GO:2001023	regulation of response to drug
0.38	GO:0043269	regulation of ion transport
0.35	GO:0006812	cation transport

0.81	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0004888	transmembrane signaling receptor activity
0.40	GO:0042166	acetylcholine binding
0.33	GO:0005515	protein binding

0.78	GO:0045211	postsynaptic membrane
0.72	GO:0030054	cell junction
0.45	GO:0005892	acetylcholine-gated channel complex
0.36	GO:0042995	cell projection
0.34	GO:0031256	leading edge membrane
0.34	GO:0009897	external side of plasma membrane
0.34	GO:0016324	apical plasma membrane
0.33	GO:0097458	neuron part

tr|T1G724|T1G724_HELRO
Uncharacterized protein
Search

OXNAD1

0.93	Oxidoreductase NAD-binding domain-containing protein 1

0.53	GO:0055114	oxidation-reduction process
0.34	GO:0010124	phenylacetate catabolic process
0.33	GO:0006091	generation of precursor metabolites and energy
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.54	GO:0016491	oxidoreductase activity
0.34	GO:0051537	2 iron, 2 sulfur cluster binding
0.33	GO:0046872	metal ion binding
0.32	GO:0020037	heme binding

0.41	GO:0005739	mitochondrion
0.32	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.54

GO:0016491

tr|T1G725|T1G725_HELRO
Uncharacterized protein
Search

0.49	Zinc finger CCCH domain-containing protein 3

0.50	GO:0016973	poly(A)+ mRNA export from nucleus
0.50	GO:0010793	regulation of mRNA export from nucleus
0.49	GO:0006378	mRNA polyadenylation
0.49	GO:0032927	positive regulation of activin receptor signaling pathway
0.41	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.34	GO:0006351	transcription, DNA-templated
0.34	GO:2001141	regulation of RNA biosynthetic process
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.54	GO:0046872	metal ion binding
0.48	GO:0070412	R-SMAD binding
0.41	GO:0004521	endoribonuclease activity
0.38	GO:0003723	RNA binding
0.34	GO:0003700	DNA binding transcription factor activity
0.34	GO:0003677	DNA binding

0.49

GO:0005847

mRNA cleavage and polyadenylation specificity factor complex

tr|T1G726|T1G726_HELRO
Uncharacterized protein
Search

0.40	6-phosphogluconolactonase (inferred by orthology to a human protein)

0.72	GO:0006098	pentose-phosphate shunt
0.60	GO:0005975	carbohydrate metabolic process
0.35	GO:0033617	mitochondrial respiratory chain complex IV assembly
0.34	GO:0015908	fatty acid transport
0.34	GO:0001676	long-chain fatty acid metabolic process

0.80	GO:0017057	6-phosphogluconolactonase activity
0.34	GO:0015245	fatty acid transmembrane transporter activity
0.34	GO:0031957	very long-chain fatty acid-CoA ligase activity
0.34	GO:0004467	long-chain fatty acid-CoA ligase activity
0.32	GO:0016740	transferase activity

0.35	GO:0034719	SMN-Sm protein complex
0.33	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.80	EC:3.1.1.31	GO:0017057
0.80	KEGG:R02035	GO:0017057

tr|T1G727|T1G727_HELRO
Uncharacterized protein
Search

0.50	GO:0007219	Notch signaling pathway
0.48	GO:0007275	multicellular organism development
0.47	GO:0007155	cell adhesion
0.46	GO:0030154	cell differentiation
0.43	GO:0050793	regulation of developmental process
0.36	GO:0007186	G-protein coupled receptor signaling pathway
0.36	GO:0001667	ameboidal-type cell migration
0.36	GO:0009888	tissue development
0.36	GO:0045199	maintenance of epithelial cell apical/basal polarity
0.36	GO:0051239	regulation of multicellular organismal process

0.69	GO:0005509	calcium ion binding
0.52	GO:0005540	hyaluronic acid binding
0.38	GO:0070001	aspartic-type peptidase activity
0.37	GO:0005112	Notch binding
0.37	GO:0004175	endopeptidase activity
0.37	GO:0019828	aspartic-type endopeptidase inhibitor activity
0.36	GO:0004930	G-protein coupled receptor activity
0.35	GO:0005201	extracellular matrix structural constituent
0.34	GO:0019899	enzyme binding
0.34	GO:0003735	structural constituent of ribosome

0.38	GO:0005576	extracellular region
0.35	GO:0016324	apical plasma membrane
0.35	GO:0015935	small ribosomal subunit
0.33	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

tr|T1G728|T1G728_HELRO
Uncharacterized protein
Search

0.60	GO:0007165	signal transduction
0.36	GO:0051056	regulation of small GTPase mediated signal transduction
0.36	GO:0043547	positive regulation of GTPase activity
0.35	GO:0006400	tRNA modification

0.36	GO:0005096	GTPase activator activity
0.35	GO:0051539	4 iron, 4 sulfur cluster binding
0.33	GO:0016740	transferase activity

0.69	GO:0005856	cytoskeleton
0.36	GO:0005634	nucleus
0.35	GO:0005829	cytosol

0.33

GO:0016740

tr|T1G729|T1G729_HELRO
Uncharacterized protein
Search

SNRNP35

0.90	Small nuclear ribonucleoprotein U11/U12 subunit 35

0.44	GO:0000398	mRNA splicing, via spliceosome
0.33	GO:0043087	regulation of GTPase activity
0.33	GO:0006413	translational initiation
0.32	GO:0007165	signal transduction

0.59	GO:0003723	RNA binding
0.33	GO:0046983	protein dimerization activity

0.56	GO:0019013	viral nucleocapsid
0.53	GO:0005689	U12-type spliceosomal complex
0.47	GO:0071011	precatalytic spliceosome
0.47	GO:0000243	commitment complex
0.46	GO:0005730	nucleolus
0.34	GO:0034693	U11/U12 snRNP
0.33	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1G730|T1G730_HELRO
Uncharacterized protein
Search

0.55	GO:0055085	transmembrane transport
0.33	GO:0008643	carbohydrate transport
0.33	GO:0015992	proton transport

0.55

GO:0005215

transporter activity

0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1G731|T1G731_HELRO
Uncharacterized protein
Search

0.52	GO:0030042	actin filament depolymerization
0.49	GO:0019417	sulfur oxidation
0.49	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.48	GO:1903305	regulation of regulated secretory pathway
0.45	GO:0001933	negative regulation of protein phosphorylation
0.35	GO:0035335	peptidyl-tyrosine dephosphorylation
0.34	GO:0007596	blood coagulation
0.34	GO:0006887	exocytosis
0.34	GO:0006006	glucose metabolic process
0.33	GO:0051301	cell division

0.64	GO:0071949	FAD binding
0.52	GO:0046872	metal ion binding
0.48	GO:0003779	actin binding
0.47	GO:0017137	Rab GTPase binding
0.47	GO:0017124	SH3 domain binding
0.46	GO:0019901	protein kinase binding
0.46	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
0.35	GO:0004725	protein tyrosine phosphatase activity
0.34	GO:0004345	glucose-6-phosphate dehydrogenase activity
0.33	GO:0050661	NADP binding

0.51	GO:1990026	hippocampal mossy fiber expansion
0.40	GO:0005829	cytosol
0.40	GO:0005654	nucleoplasm
0.37	GO:0005886	plasma membrane
0.36	GO:0005856	cytoskeleton
0.36	GO:0030496	midbody
0.34	GO:0005938	cell cortex
0.33	GO:0099512	supramolecular fiber
0.30	GO:0031224	intrinsic component of membrane

0.46

EC:1.14.13

GO:0016709

tr|T1G732|T1G732_HELRO
Uncharacterized protein
Search

LOC106160080

0.88	coiled-coil domain-containing protein 93-like isoform X2

tr|T1G733|T1G733_HELRO
Uncharacterized protein
Search

GINS1

0.83	DNA replication complex GINS protein PSF1

0.66	GO:0006260	DNA replication
0.51	GO:0001833	inner cell mass cell proliferation
0.47	GO:0022616	DNA strand elongation
0.46	GO:0032392	DNA geometric change
0.45	GO:1903047	mitotic cell cycle process
0.44	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle
0.34	GO:0006281	DNA repair
0.33	GO:0051225	spindle assembly
0.32	GO:0000280	nuclear division
0.32	GO:0005975	carbohydrate metabolic process

0.50	GO:0043138	3'-5' DNA helicase activity
0.34	GO:0005515	protein binding
0.34	GO:0003682	chromatin binding
0.33	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed
0.33	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.31	GO:0030554	adenyl nucleotide binding
0.31	GO:0032555	purine ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.85	GO:0000811	GINS complex
0.37	GO:0005737	cytoplasm
0.33	GO:0071162	CMG complex
0.33	GO:0031298	replication fork protection complex
0.33	GO:0005871	kinesin complex
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:3.6.4.4

GO:0008574

tr|T1G734|T1G734_HELRO
Uncharacterized protein
Search

0.71	Cell cycle control protein 50A

0.49	GO:0015914	phospholipid transport
0.37	GO:0070863	positive regulation of protein exit from endoplasmic reticulum
0.34	GO:0036010	protein localization to endosome
0.34	GO:0071705	nitrogen compound transport
0.34	GO:0010976	positive regulation of neuron projection development
0.33	GO:0034204	lipid translocation
0.33	GO:0006313	transposition, DNA-mediated
0.33	GO:0006855	drug transmembrane transport

0.37	GO:0015247	aminophospholipid transmembrane transporter activity
0.33	GO:0004803	transposase activity
0.33	GO:0008483	transaminase activity
0.33	GO:0030170	pyridoxal phosphate binding

0.33	GO:0016324	apical plasma membrane
0.33	GO:0030658	transport vesicle membrane
0.33	GO:0005794	Golgi apparatus
0.33	GO:0005783	endoplasmic reticulum
0.30	GO:0016021	integral component of membrane

0.33

EC:2.6.1

GO:0008483

tr|T1G735|T1G735_HELRO
Uncharacterized protein
Search

SLC38A9

0.88	Sodium-coupled neutral amino acid transporter 9

0.49	GO:0071230	cellular response to amino acid stimulus
0.48	GO:0032008	positive regulation of TOR signaling
0.45	GO:0003333	amino acid transmembrane transport
0.36	GO:0016241	regulation of macroautophagy
0.36	GO:0007050	cell cycle arrest

0.45	GO:0015171	amino acid transmembrane transporter activity
0.34	GO:0005515	protein binding
0.33	GO:0016787	hydrolase activity

0.50	GO:0071986	Ragulator complex
0.47	GO:0005764	lysosome
0.44	GO:0098852	lytic vacuole membrane
0.42	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0016787

tr|T1G736|T1G736_HELRO
Uncharacterized protein
Search

0.70	GO:0006541	glutamine metabolic process
0.43	GO:0001967	suckling behavior
0.43	GO:0002087	regulation of respiratory gaseous exchange by neurological system process
0.42	GO:0006537	glutamate biosynthetic process
0.42	GO:0051289	protein homotetramerization
0.41	GO:0009065	glutamine family amino acid catabolic process
0.40	GO:0007268	chemical synaptic transmission
0.37	GO:0014047	glutamate secretion
0.35	GO:0071805	potassium ion transmembrane transport
0.34	GO:0034765	regulation of ion transmembrane transport

0.78	GO:0004359	glutaminase activity
0.36	GO:0005249	voltage-gated potassium channel activity
0.36	GO:0005509	calcium ion binding
0.34	GO:0016491	oxidoreductase activity
0.34	GO:0005515	protein binding
0.33	GO:0004067	asparaginase activity
0.33	GO:0051287	NAD binding
0.33	GO:0000287	magnesium ion binding
0.33	GO:0015248	sterol transporter activity
0.32	GO:0008289	lipid binding

0.39	GO:0005759	mitochondrial matrix
0.34	GO:0005829	cytosol
0.33	GO:0032541	cortical endoplasmic reticulum
0.32	GO:0005935	cellular bud neck
0.32	GO:0005635	nuclear envelope
0.31	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.78

EC:3.5.1.2

GO:0004359

tr|T1G737|T1G737_HELRO
Uncharacterized protein
Search

0.80	Zinc binding domain-containing protein (Fragment)

0.34

GO:0010469

regulation of receptor activity

0.61	GO:0008270	zinc ion binding
0.50	GO:0003676	nucleic acid binding
0.34	GO:0008083	growth factor activity

0.33	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

tr|T1G738|T1G738_HELRO
Uncharacterized protein
Search

0.54	Counting factor associated protein D

0.61	GO:0006508	proteolysis
0.37	GO:0044257	cellular protein catabolic process
0.33	GO:0007017	microtubule-based process
0.33	GO:0007010	cytoskeleton organization

0.72	GO:0008234	cysteine-type peptidase activity
0.36	GO:0004175	endopeptidase activity
0.35	GO:0008289	lipid binding
0.34	GO:0005200	structural constituent of cytoskeleton
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.38	GO:0005764	lysosome
0.37	GO:0005615	extracellular space
0.34	GO:0005874	microtubule
0.30	GO:0016020	membrane

0.72

GO:0008234

tr|T1G739|T1G739_HELRO
Uncharacterized protein
Search

HID1

0.96	HID1 domain containing

0.80	GO:0031001	response to brefeldin A
0.63	GO:0006886	intracellular protein transport

0.35	GO:0005515	protein binding
0.30	GO:0003824	catalytic activity

0.79	GO:0000138	Golgi trans cisterna
0.78	GO:0005797	Golgi medial cisterna
0.75	GO:0090498	extrinsic component of Golgi membrane
0.70	GO:0005881	cytoplasmic microtubule
0.59	GO:0005829	cytosol
0.40	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

tr|T1G740|T1G740_HELRO
Uncharacterized protein
Search

UPP1

0.54	Uridine phosphorylase

0.74	GO:0009166	nucleotide catabolic process
0.66	GO:0009116	nucleoside metabolic process
0.58	GO:0032262	pyrimidine nucleotide salvage
0.55	GO:0009174	pyrimidine ribonucleoside monophosphate biosynthetic process
0.54	GO:0009218	pyrimidine ribonucleotide metabolic process
0.52	GO:1901659	glycosyl compound biosynthetic process
0.50	GO:0009260	ribonucleotide biosynthetic process
0.42	GO:0042332	gravitaxis
0.37	GO:0072529	pyrimidine-containing compound catabolic process
0.37	GO:1901658	glycosyl compound catabolic process

0.82	GO:0004850	uridine phosphorylase activity
0.36	GO:0004386	helicase activity
0.34	GO:0004454	ketohexokinase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0003677	DNA binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.49	GO:0005737	cytoplasm
0.36	GO:0005654	nucleoplasm
0.36	GO:0045098	type III intermediate filament
0.33	GO:0048475	coated membrane
0.32	GO:0098796	membrane protein complex
0.30	GO:0016021	integral component of membrane

0.82

EC:2.4.2.3

GO:0004850

tr|T1G741|T1G741_HELRO
Uncharacterized protein
Search

0.54	LIM domain-containing protein jub

0.56	GO:0035331	negative regulation of hippo signaling
0.55	GO:2000637	positive regulation of gene silencing by miRNA
0.54	GO:0035313	wound healing, spreading of epidermal cells
0.53	GO:0048041	focal adhesion assembly
0.53	GO:1900037	regulation of cellular response to hypoxia
0.52	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.52	GO:0030032	lamellipodium assembly
0.52	GO:0001666	response to hypoxia
0.51	GO:0035195	gene silencing by miRNA
0.51	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling

0.54	GO:0046872	metal ion binding
0.53	GO:0045294	alpha-catenin binding
0.52	GO:0003714	transcription corepressor activity
0.49	GO:0051015	actin filament binding
0.48	GO:0003682	chromatin binding
0.42	GO:0031005	filamin binding
0.37	GO:0003677	DNA binding
0.37	GO:0003700	DNA binding transcription factor activity
0.36	GO:0005096	GTPase activator activity
0.30	GO:0003824	catalytic activity

0.53	GO:0005912	adherens junction
0.52	GO:0030055	cell-substrate junction
0.52	GO:0000932	P-body
0.50	GO:0030027	lamellipodium
0.50	GO:0005911	cell-cell junction
0.49	GO:0005667	transcription factor complex
0.47	GO:0005634	nucleus
0.46	GO:0005794	Golgi apparatus
0.45	GO:0005829	cytosol
0.42	GO:0044430	cytoskeletal part

tr|T1G742|T1G742_HELRO
Uncharacterized protein
Search

UQCR10

0.91	Mitochondrial ubiquinol-cytochrome c reductase

0.74	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c
0.49	GO:0017062	respiratory chain complex III assembly
0.49	GO:0097033	mitochondrial respiratory chain complex III biogenesis
0.48	GO:0033108	mitochondrial respiratory chain complex assembly
0.42	GO:0009060	aerobic respiration

0.46	GO:0016681	oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor
0.41	GO:0009055	electron transfer activity
0.35	GO:0003924	GTPase activity
0.35	GO:0032550	purine ribonucleoside binding
0.35	GO:0032561	guanyl ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.83	GO:0005750	mitochondrial respiratory chain complex III
0.42	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.46

EC:1.10.2

GO:0016681

tr|T1G743|T1G743_HELRO
Uncharacterized protein
Search

tr|T1G744|T1G744_HELRO
Uncharacterized protein
Search

tr|T1G745|T1G745_HELRO
Uncharacterized protein
Search

0.76	Jumonji C domain containing histone demethylase 1 homolog D (Fragment)

0.58	GO:0033169	histone H3-K9 demethylation
0.57	GO:0035574	histone H4-K20 demethylation
0.57	GO:0071557	histone H3-K27 demethylation
0.55	GO:0070544	histone H3-K36 demethylation
0.52	GO:0032259	methylation
0.48	GO:0045893	positive regulation of transcription, DNA-templated
0.45	GO:0030901	midbrain development
0.40	GO:0055114	oxidation-reduction process
0.37	GO:0060319	primitive erythrocyte differentiation
0.37	GO:0048703	embryonic viscerocranium morphogenesis

0.58	GO:0032454	histone demethylase activity (H3-K9 specific)
0.58	GO:0035575	histone demethylase activity (H4-K20 specific)
0.57	GO:0071558	histone demethylase activity (H3-K27 specific)
0.55	GO:0051864	histone demethylase activity (H3-K36 specific)
0.52	GO:0035064	methylated histone binding
0.52	GO:0008168	methyltransferase activity
0.49	GO:0046872	metal ion binding
0.34	GO:0003682	chromatin binding
0.34	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.32	GO:0003677	DNA binding

0.55	GO:0005634	nucleus
0.45	GO:0043233	organelle lumen
0.42	GO:0043232	intracellular non-membrane-bounded organelle
0.41	GO:0044446	intracellular organelle part
0.33	GO:0012505	endomembrane system
0.33	GO:0031090	organelle membrane
0.33	GO:0031975	envelope
0.30	GO:0031224	intrinsic component of membrane

0.55

EC:1.14.11.27

GO:0051864

tr|T1G746|T1G746_HELRO
Uncharacterized protein
Search

0.44	GO:0035335	peptidyl-tyrosine dephosphorylation
0.43	GO:0008652	cellular amino acid biosynthetic process

0.45	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.44	GO:0004725	protein tyrosine phosphatase activity
0.43	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
0.36	GO:0052689	carboxylic ester hydrolase activity

0.40	GO:0005763	mitochondrial small ribosomal subunit
0.30	GO:0016020	membrane

0.45	EC:3.1.3	GO:0008138
0.36	KEGG:R00630	GO:0052689

tr|T1G747|T1G747_HELRO
Kinesin-like protein
Search

0.37	Osmotic avoidance abnormal protein 3

0.74

GO:0007018

microtubule-based movement

0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

tr|T1G748|T1G748_HELRO
Methionine aminopeptidase
Search

0.46	Methionine aminopeptidase

0.74	GO:0070084	protein initiator methionine removal
0.60	GO:0006508	proteolysis
0.34	GO:0031365	N-terminal protein amino acid modification

0.74	GO:0070006	metalloaminopeptidase activity
0.54	GO:0046872	metal ion binding
0.33	GO:0016788	hydrolase activity, acting on ester bonds

0.35	GO:0009507	chloroplast
0.33	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:3.1

GO:0016788

tr|T1G749|T1G749_HELRO
Uncharacterized protein
Search

0.77	GO:0016055	Wnt signaling pathway
0.70	GO:0007275	multicellular organism development
0.42	GO:0007186	G-protein coupled receptor signaling pathway

0.47	GO:0017147	Wnt-protein binding
0.47	GO:0042813	Wnt-activated receptor activity
0.43	GO:0004930	G-protein coupled receptor activity

0.43	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

tr|T1G750|T1G750_HELRO
Uncharacterized protein
Search

IMPA1

0.41	Inositol-1-monophosphatase

0.80	GO:0006021	inositol biosynthetic process
0.79	GO:0046855	inositol phosphate dephosphorylation
0.75	GO:0046854	phosphatidylinositol phosphorylation
0.45	GO:0006661	phosphatidylinositol biosynthetic process
0.42	GO:0007165	signal transduction
0.41	GO:0043052	thermotaxis
0.39	GO:0035418	protein localization to synapse
0.37	GO:0006935	chemotaxis
0.35	GO:0010226	response to lithium ion
0.33	GO:0006310	DNA recombination

0.79	GO:0008934	inositol monophosphate 1-phosphatase activity
0.79	GO:0052832	inositol monophosphate 3-phosphatase activity
0.79	GO:0052833	inositol monophosphate 4-phosphatase activity
0.53	GO:0046872	metal ion binding
0.44	GO:0042803	protein homodimerization activity
0.34	GO:0000150	recombinase activity
0.33	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.32	GO:0003677	DNA binding

0.37	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.34	GO:0043025	neuronal cell body
0.34	GO:0030424	axon
0.32	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016020	membrane

0.79

EC:3.1.3.25

GO:0008934

tr|T1G751|T1G751_HELRO
Uncharacterized protein
Search

DUS2

0.45	Trna dihydrouridine synthase

0.77	GO:0002943	tRNA dihydrouridine synthesis
0.53	GO:0055114	oxidation-reduction process
0.49	GO:0006469	negative regulation of protein kinase activity
0.48	GO:0060548	negative regulation of cell death
0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression

0.77	GO:0017150	tRNA dihydrouridine synthase activity
0.66	GO:0050660	flavin adenine dinucleotide binding
0.50	GO:0004860	protein kinase inhibitor activity
0.48	GO:0003725	double-stranded RNA binding
0.34	GO:0003700	DNA binding transcription factor activity
0.34	GO:0003677	DNA binding

0.45	GO:0005829	cytosol
0.42	GO:0005739	mitochondrion
0.33	GO:0005783	endoplasmic reticulum
0.30	GO:0016020	membrane

tr|T1G752|T1G752_HELRO
Uncharacterized protein
Search

ERCC8

0.56	Cockayne syndrome WD repeat protein CSA

0.84	GO:0051865	protein autoubiquitination
0.83	GO:0010165	response to X-ray
0.80	GO:0000209	protein polyubiquitination
0.80	GO:0009411	response to UV
0.78	GO:0006283	transcription-coupled nucleotide-excision repair
0.76	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.70	GO:0006979	response to oxidative stress
0.50	GO:0045739	positive regulation of DNA repair
0.49	GO:0010996	response to auditory stimulus
0.45	GO:0014070	response to organic cyclic compound

0.74	GO:0032403	protein complex binding
0.72	GO:0004842	ubiquitin-protein transferase activity
0.41	GO:0003678	DNA helicase activity
0.40	GO:0008094	DNA-dependent ATPase activity
0.40	GO:0009922	fatty acid elongase activity
0.39	GO:0102756	very-long-chain 3-ketoacyl-CoA synthase activity
0.39	GO:0102338	3-oxo-lignoceronyl-CoA synthase activity
0.39	GO:0102336	3-oxo-arachidoyl-CoA synthase activity
0.39	GO:0102337	3-oxo-cerotoyl-CoA synthase activity
0.34	GO:0043531	ADP binding

0.85	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex
0.84	GO:0000109	nucleotide-excision repair complex
0.83	GO:0016363	nuclear matrix
0.48	GO:0043204	perikaryon
0.38	GO:0005654	nucleoplasm
0.37	GO:0005783	endoplasmic reticulum
0.30	GO:0016020	membrane

0.39	EC:2.3.1.199	GO:0102338
0.72	KEGG:R03876	GO:0004842

tr|T1G753|T1G753_HELRO
Uncharacterized protein
Search

UQCC1

0.72	Ubiquinol-cytochrome c reductase complex assembly factor 1

0.81	GO:0070131	positive regulation of mitochondrial translation
0.78	GO:0017062	respiratory chain complex III assembly
0.78	GO:0097033	mitochondrial respiratory chain complex III biogenesis
0.75	GO:0033108	mitochondrial respiratory chain complex assembly
0.46	GO:0007030	Golgi organization
0.38	GO:0032933	SREBP signaling pathway
0.38	GO:0008203	cholesterol metabolic process
0.37	GO:0006313	transposition, DNA-mediated
0.33	GO:0055114	oxidation-reduction process

0.38	GO:0043022	ribosome binding
0.38	GO:0015485	cholesterol binding
0.37	GO:0004803	transposase activity
0.33	GO:0016491	oxidoreductase activity

0.65	GO:0031410	cytoplasmic vesicle
0.58	GO:0005739	mitochondrion
0.57	GO:0031090	organelle membrane
0.57	GO:0031967	organelle envelope
0.41	GO:0061671	Cbp3p-Cbp6 complex
0.39	GO:0000324	fungal-type vacuole
0.39	GO:0000313	organellar ribosome
0.39	GO:0044437	vacuolar part
0.38	GO:0098805	whole membrane
0.37	GO:0043233	organelle lumen

0.33

GO:0016491

tr|T1G754|T1G754_HELRO
Uncharacterized protein
Search

WDR47

0.50	Wd repeat-containing protein 47

0.80	GO:0007219	Notch signaling pathway
0.70	GO:0045892	negative regulation of transcription, DNA-templated
0.51	GO:0055085	transmembrane transport
0.39	GO:0006438	valyl-tRNA aminoacylation
0.39	GO:0106074	aminoacyl-tRNA metabolism involved in translational fidelity

0.75	GO:0003682	chromatin binding
0.61	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.52	GO:0032559	adenyl ribonucleotide binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0004832	valine-tRNA ligase activity
0.39	GO:0002161	aminoacyl-tRNA editing activity

0.30

GO:0016020

membrane

0.40	EC:6.1.1.9	GO:0004832
0.40	KEGG:R03665	GO:0004832

tr|T1G755|T1G755_HELRO
Uncharacterized protein
Search

0.76	Translocon-associated complex TRAP alpha subunit

0.47	GO:0071391	cellular response to estrogen stimulus
0.42	GO:0006886	intracellular protein transport
0.40	GO:0090150	establishment of protein localization to membrane

0.72	GO:0005789	endoplasmic reticulum membrane
0.47	GO:0045169	fusome
0.41	GO:0005801	cis-Golgi network
0.30	GO:0031224	intrinsic component of membrane

tr|T1G756|T1G756_HELRO
Uncharacterized protein
Search

0.37	molybdate-anion transporter

0.77	GO:0015689	molybdate ion transport
0.33	GO:0006886	intracellular protein transport
0.33	GO:0016192	vesicle-mediated transport

0.79

GO:0015098

molybdate ion transmembrane transporter activity

0.34	GO:0005794	Golgi apparatus
0.30	GO:0016021	integral component of membrane

tr|T1G757|T1G757_HELRO
Uncharacterized protein
Search

ISL2

0.92	Insulin protein enhancer protein ISL-2

0.60	GO:0021524	visceral motor neuron differentiation
0.58	GO:0021520	spinal cord motor neuron cell fate specification
0.57	GO:0031290	retinal ganglion cell axon guidance
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0045665	negative regulation of neuron differentiation
0.45	GO:0048934	peripheral nervous system neuron differentiation
0.44	GO:0071657	positive regulation of granulocyte colony-stimulating factor production
0.44	GO:0060913	cardiac cell fate determination

0.64	GO:0043565	sequence-specific DNA binding
0.53	GO:0046872	metal ion binding
0.45	GO:0042578	phosphoric ester hydrolase activity
0.43	GO:0043425	bHLH transcription factor binding
0.43	GO:1990841	promoter-specific chromatin binding
0.42	GO:0001105	RNA polymerase II transcription coactivator activity
0.42	GO:0001102	RNA polymerase II activating transcription factor binding
0.42	GO:0035326	enhancer binding
0.39	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.39	GO:0070013	intracellular organelle lumen
0.37	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.45

EC:3.1

GO:0042578

tr|T1G758|T1G758_HELRO
Uncharacterized protein
Search

0.57	Zinc finger MYM-type protein 1

0.68	GO:0046983	protein dimerization activity
0.38	GO:0008270	zinc ion binding

tr|T1G759|T1G759_HELRO
Uncharacterized protein
Search

0.55	cAMP-dependent protein kinase catalytic subunit alpha

0.63	GO:0006468	protein phosphorylation
0.42	GO:0008359	regulation of bicoid mRNA localization
0.42	GO:0048682	sprouting of injured axon
0.42	GO:0007615	anesthesia-resistant memory
0.41	GO:0007228	positive regulation of hh target transcription factor activity
0.41	GO:0007448	anterior/posterior pattern specification, imaginal disc
0.41	GO:0008103	oocyte microtubule cytoskeleton polarization
0.41	GO:0007317	regulation of pole plasm oskar mRNA localization
0.41	GO:0040040	thermosensory behavior
0.41	GO:0008355	olfactory learning

0.70	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0060089	molecular transducer activity
0.33	GO:0005515	protein binding

0.39	GO:0030425	dendrite
0.39	GO:0044297	cell body
0.35	GO:0005886	plasma membrane
0.34	GO:0005952	cAMP-dependent protein kinase complex
0.34	GO:0005737	cytoplasm

0.70

GO:0004674

tr|T1G760|T1G760_HELRO
Uncharacterized protein
Search

RDH13

0.66	3-keto-steroid reductase

0.48	GO:0055114	oxidation-reduction process
0.43	GO:0010842	retina layer formation
0.42	GO:0009644	response to high light intensity
0.42	GO:0042462	eye photoreceptor cell development
0.36	GO:0006511	ubiquitin-dependent protein catabolic process

0.49	GO:0016491	oxidoreductase activity
0.37	GO:0004312	fatty acid synthase activity
0.34	GO:0008270	zinc ion binding

0.37	GO:0005739	mitochondrion
0.34	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.49

GO:0016491

tr|T1G761|T1G761_HELRO
Uncharacterized protein
Search

0.72	Oligomeric Golgi complex subunit

0.69	GO:0006886	intracellular protein transport
0.53	GO:0007030	Golgi organization
0.53	GO:0006891	intra-Golgi vesicle-mediated transport
0.51	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.50	GO:0050821	protein stabilization
0.50	GO:0006888	ER to Golgi vesicle-mediated transport
0.48	GO:0006486	protein glycosylation
0.47	GO:0033365	protein localization to organelle
0.43	GO:0007112	male meiosis cytokinesis
0.42	GO:0033227	dsRNA transport

0.48	GO:0008565	protein transporter activity
0.33	GO:0003676	nucleic acid binding
0.33	GO:0005515	protein binding

0.82	GO:0005801	cis-Golgi network
0.55	GO:0017119	Golgi transport complex
0.46	GO:0005829	cytosol
0.40	GO:0005886	plasma membrane
0.36	GO:0031984	organelle subcompartment
0.36	GO:0098588	bounding membrane of organelle
0.35	GO:0005783	endoplasmic reticulum
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0031966	mitochondrial membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1G762|T1G762_HELRO
Uncharacterized protein
Search

tr|T1G763|T1G763_HELRO
Uncharacterized protein
Search

tr|T1G764|T1G764_HELRO
Uncharacterized protein
Search

tr|T1G765|T1G765_HELRO
Uncharacterized protein
Search

0.79	GO:0046475	glycerophospholipid catabolic process
0.40	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.40	GO:0072502	cellular trivalent inorganic anion homeostasis
0.40	GO:0072501	cellular divalent inorganic anion homeostasis
0.40	GO:0030320	cellular monovalent inorganic anion homeostasis
0.40	GO:0055062	phosphate ion homeostasis
0.35	GO:0048280	vesicle fusion with Golgi apparatus
0.34	GO:0006086	acetyl-CoA biosynthetic process from pyruvate
0.34	GO:0006886	intracellular protein transport
0.32	GO:1903506	regulation of nucleic acid-templated transcription

0.81	GO:0047389	glycerophosphocholine phosphodiesterase activity
0.75	GO:2001070	starch binding
0.43	GO:0033897	ribonuclease T2 activity
0.39	GO:0008889	glycerophosphodiester phosphodiesterase activity
0.37	GO:0003723	RNA binding
0.34	GO:0017022	myosin binding
0.34	GO:0008565	protein transporter activity
0.34	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity
0.33	GO:0043565	sequence-specific DNA binding
0.33	GO:0005198	structural molecule activity

0.34	GO:0000139	Golgi membrane
0.34	GO:0005882	intermediate filament
0.33	GO:0005634	nucleus

0.81

EC:3.1.4.2

GO:0047389

tr|T1G766|T1G766_HELRO
Uncharacterized protein
Search

0.46	Glutaredoxin

0.69	GO:0045454	cell redox homeostasis
0.61	GO:0022900	electron transport chain
0.39	GO:0031163	metallo-sulfur cluster assembly
0.37	GO:0006970	response to osmotic stress
0.37	GO:0006790	sulfur compound metabolic process
0.37	GO:0030097	hemopoiesis
0.37	GO:0034599	cellular response to oxidative stress
0.37	GO:0051188	cofactor biosynthetic process
0.35	GO:0097428	protein maturation by iron-sulfur cluster transfer
0.34	GO:0001189	RNA polymerase I transcriptional preinitiation complex assembly

0.72	GO:0015035	protein disulfide oxidoreductase activity
0.65	GO:0051537	2 iron, 2 sulfur cluster binding
0.62	GO:0009055	electron transfer activity
0.51	GO:0046872	metal ion binding
0.36	GO:0015038	glutathione disulfide oxidoreductase activity
0.35	GO:0004491	methylmalonate-semialdehyde dehydrogenase (acylating) activity
0.34	GO:0001187	RNA polymerase I CORE element sequence-specific DNA binding
0.33	GO:0051287	NAD binding
0.32	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

0.37	GO:0005739	mitochondrion
0.36	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part
0.33	GO:0005667	transcription factor complex
0.32	GO:0005634	nucleus
0.32	GO:0043232	intracellular non-membrane-bounded organelle

0.35

EC:1.2.1.27

GO:0004491

tr|T1G767|T1G767_HELRO
Uncharacterized protein
Search

0.50	GO:0009405	pathogenesis
0.48	GO:0006468	protein phosphorylation
0.38	GO:0018202	peptidyl-histidine modification
0.37	GO:0005975	carbohydrate metabolic process
0.36	GO:0000160	phosphorelay signal transduction system
0.35	GO:0055085	transmembrane transport

0.50	GO:0004674	protein serine/threonine kinase activity
0.43	GO:0032559	adenyl ribonucleotide binding
0.43	GO:0008144	drug binding
0.43	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0003935	GTP cyclohydrolase II activity
0.42	GO:0008686	3,4-dihydroxy-2-butanone-4-phosphate synthase activity
0.41	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.40	GO:0042302	structural constituent of cuticle
0.39	GO:0046983	protein dimerization activity
0.37	GO:0004673	protein histidine kinase activity

0.33	GO:0005622	intracellular
0.30	GO:0016020	membrane

0.50	EC:2.7.11	GO:0004674
0.42	KEGG:R00425	GO:0003935

tr|T1G768|T1G768_HELRO
Uncharacterized protein
Search

CRELD2

0.68	Cysteine rich with EGF like domains 2

0.43	GO:0030198	extracellular matrix organization
0.42	GO:0007160	cell-matrix adhesion
0.40	GO:0010952	positive regulation of peptidase activity
0.38	GO:0036363	transforming growth factor beta activation
0.38	GO:1902462	positive regulation of mesenchymal stem cell proliferation
0.38	GO:2000741	positive regulation of mesenchymal stem cell differentiation
0.37	GO:0060958	endocardial cell development
0.37	GO:0003250	regulation of cell proliferation involved in heart valve morphogenesis
0.37	GO:0003160	endocardium morphogenesis
0.37	GO:0048570	notochord morphogenesis

0.70	GO:0005509	calcium ion binding
0.49	GO:0005201	extracellular matrix structural constituent
0.40	GO:0016504	peptidase activator activity
0.37	GO:0050431	transforming growth factor beta binding
0.34	GO:0008061	chitin binding
0.34	GO:0004672	protein kinase activity
0.33	GO:0032403	protein complex binding
0.33	GO:0001968	fibronectin binding
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0008022	protein C-terminus binding

0.52	GO:0044421	extracellular region part
0.41	GO:0005783	endoplasmic reticulum
0.40	GO:0005794	Golgi apparatus
0.34	GO:0005886	plasma membrane
0.33	GO:0031982	vesicle
0.32	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.32

GO:0004252

tr|T1G769|T1G769_HELRO
Uncharacterized protein
Search

0.46	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.44	GO:0007528	neuromuscular junction development
0.43	GO:0030198	extracellular matrix organization
0.42	GO:0071230	cellular response to amino acid stimulus
0.42	GO:0061304	retinal blood vessel morphogenesis
0.41	GO:0072001	renal system development
0.41	GO:0001569	branching involved in blood vessel morphogenesis
0.40	GO:0007399	nervous system development
0.40	GO:0060322	head development
0.37	GO:0052548	regulation of endopeptidase activity

0.65	GO:0005201	extracellular matrix structural constituent
0.43	GO:0042302	structural constituent of cuticle
0.42	GO:0048407	platelet-derived growth factor binding
0.36	GO:0005178	integrin binding
0.36	GO:0004867	serine-type endopeptidase inhibitor activity
0.33	GO:0005509	calcium ion binding
0.33	GO:0097493	structural molecule activity conferring elasticity
0.33	GO:0008270	zinc ion binding
0.33	GO:0004181	metallocarboxypeptidase activity
0.32	GO:0004185	serine-type carboxypeptidase activity

0.70	GO:0005581	collagen trimer
0.59	GO:0005604	basement membrane
0.47	GO:0098645	collagen network
0.39	GO:0031594	neuromuscular junction
0.39	GO:0005615	extracellular space
0.34	GO:0005783	endoplasmic reticulum
0.33	GO:0030056	hemidesmosome
0.33	GO:0070013	intracellular organelle lumen
0.32	GO:0044446	intracellular organelle part
0.32	GO:0005840	ribosome

0.33

EC:3.4.17

GO:0004181

tr|T1G770|T1G770_HELRO
Uncharacterized protein
Search

0.54	Discoidin domain-containing receptor 2

0.70	GO:0018108	peptidyl-tyrosine phosphorylation
0.59	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.42	GO:0045200	establishment of neuroblast polarity
0.41	GO:0007411	axon guidance
0.39	GO:0016477	cell migration
0.36	GO:0045597	positive regulation of cell differentiation
0.36	GO:0051240	positive regulation of multicellular organismal process
0.36	GO:2000026	regulation of multicellular organismal development
0.36	GO:0051130	positive regulation of cellular component organization
0.36	GO:1903036	positive regulation of response to wounding

0.72	GO:0004713	protein tyrosine kinase activity
0.59	GO:0038064	collagen receptor activity
0.59	GO:0019199	transmembrane receptor protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0005109	frizzled binding
0.40	GO:0017147	Wnt-protein binding
0.35	GO:0019838	growth factor binding

0.50	GO:0005887	integral component of plasma membrane
0.41	GO:0032809	neuronal cell body membrane
0.40	GO:0030424	axon
0.40	GO:0031594	neuromuscular junction
0.39	GO:0030425	dendrite
0.35	GO:0043204	perikaryon
0.34	GO:0005856	cytoskeleton
0.34	GO:0030054	cell junction

0.72

GO:0004713

tr|T1G771|T1G771_HELRO
Uncharacterized protein
Search

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.39	GO:0060243	negative regulation of cell growth involved in contact inhibition
0.39	GO:0090675	intermicrovillar adhesion
0.39	GO:0032532	regulation of microvillus length
0.39	GO:0044331	cell-cell adhesion mediated by cadherin
0.38	GO:0048856	anatomical structure development
0.37	GO:0030154	cell differentiation
0.37	GO:0023052	signaling
0.37	GO:0007154	cell communication
0.36	GO:0032501	multicellular organismal process

0.70	GO:0005509	calcium ion binding
0.37	GO:0050839	cell adhesion molecule binding
0.36	GO:0004930	G-protein coupled receptor activity
0.35	GO:0015116	sulfate transmembrane transporter activity
0.34	GO:0004867	serine-type endopeptidase inhibitor activity
0.30	GO:0003824	catalytic activity

0.56	GO:0005886	plasma membrane
0.39	GO:0089717	spanning component of membrane
0.38	GO:0045177	apical part of cell
0.38	GO:0120038	plasma membrane bounded cell projection part
0.38	GO:0005902	microvillus
0.38	GO:0005903	brush border
0.36	GO:0044291	cell-cell contact zone
0.35	GO:0030427	site of polarized growth
0.35	GO:0043005	neuron projection
0.32	GO:0005622	intracellular

tr|T1G772|T1G772_HELRO
Uncharacterized protein
Search

RPL35

0.75	Large subunit ribosomal protein L35e

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.46	GO:0042273	ribosomal large subunit biogenesis
0.43	GO:0016072	rRNA metabolic process
0.40	GO:0030218	erythrocyte differentiation
0.39	GO:0043009	chordate embryonic development
0.38	GO:0051726	regulation of cell cycle
0.35	GO:0071493	cellular response to UV-B

0.64	GO:0003735	structural constituent of ribosome
0.46	GO:0003729	mRNA binding
0.34	GO:0043021	ribonucleoprotein complex binding

0.61	GO:0005840	ribosome
0.45	GO:0044445	cytosolic part
0.40	GO:0044446	intracellular organelle part
0.34	GO:0005791	rough endoplasmic reticulum
0.34	GO:0098562	cytoplasmic side of membrane
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0043233	organelle lumen
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

tr|T1G773|T1G773_HELRO
Uncharacterized protein
Search

0.33	Zinc finger protein (Fragment)

0.45	GO:0045925	positive regulation of female receptivity
0.44	GO:0016319	mushroom body development
0.43	GO:0008344	adult locomotory behavior
0.41	GO:0031175	neuron projection development
0.40	GO:1903506	regulation of nucleic acid-templated transcription
0.40	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.39	GO:0010468	regulation of gene expression
0.35	GO:0006351	transcription, DNA-templated
0.34	GO:0040034	regulation of development, heterochronic
0.34	GO:1902680	positive regulation of RNA biosynthetic process

0.51	GO:0003676	nucleic acid binding
0.38	GO:0046872	metal ion binding
0.35	GO:0003700	DNA binding transcription factor activity
0.33	GO:0005319	lipid transporter activity
0.32	GO:0008168	methyltransferase activity

0.38	GO:0005634	nucleus
0.35	GO:0005694	chromosome
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0044446	intracellular organelle part
0.31	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0008168

tr|T1G774|T1G774_HELRO
Uncharacterized protein
Search

LYRM1

0.97	LYR motif-containing protein 1

0.82	GO:0030496	midbody
0.69	GO:0005654	nucleoplasm
0.61	GO:0005739	mitochondrion

tr|T1G775|T1G775_HELRO
Uncharacterized protein
Search

0.61	GO:0042981	regulation of apoptotic process
0.52	GO:0034220	ion transmembrane transport

0.59

GO:0005216

ion channel activity

0.30

GO:0031224

intrinsic component of membrane

tr|T1G776|T1G776_HELRO
Protein kinase C
Search

0.83	Calcium-dependent protein kinase C

0.63	GO:0006468	protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.54	GO:0018210	peptidyl-threonine modification
0.53	GO:0045766	positive regulation of angiogenesis
0.51	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway
0.51	GO:0034351	negative regulation of glial cell apoptotic process
0.51	GO:0090330	regulation of platelet aggregation
0.50	GO:0002159	desmosome assembly
0.49	GO:0001938	positive regulation of endothelial cell proliferation
0.49	GO:0010595	positive regulation of endothelial cell migration

0.83	GO:0004697	protein kinase C activity
0.62	GO:0008270	zinc ion binding
0.58	GO:0035403	histone kinase activity (H3-T6 specific)
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0008144	drug binding
0.47	GO:0019899	enzyme binding
0.46	GO:0050681	androgen receptor binding
0.45	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity

0.47	GO:0005829	cytosol
0.44	GO:0005886	plasma membrane
0.43	GO:0005783	endoplasmic reticulum
0.40	GO:0005654	nucleoplasm
0.38	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0120025	plasma membrane bounded cell projection
0.38	GO:0070062	extracellular exosome
0.38	GO:0043025	neuronal cell body
0.36	GO:0044463	cell projection part
0.35	GO:0045177	apical part of cell

0.83

EC:2.7.11.13

GO:0004697

tr|T1G777|T1G777_HELRO
Uncharacterized protein
Search

0.40	Nuclear transport factor 2

tr|T1G778|T1G778_HELRO
Uncharacterized protein
Search

0.12	Proline-rich coiled-coil 1

0.87	GO:0034199	activation of protein kinase A activity
0.86	GO:0001757	somite specification
0.85	GO:0010669	epithelial structure maintenance

0.85

GO:0034237

protein kinase A regulatory subunit binding

0.70	GO:0005794	Golgi apparatus
0.30	GO:0016020	membrane

tr|T1G779|T1G779_HELRO
Uncharacterized protein
Search

tr|T1G780|T1G780_HELRO
Uncharacterized protein
Search

B9D1

0.96	B9 domain-containing protein 1

0.84	GO:0060563	neuroepithelial cell differentiation
0.84	GO:0042733	embryonic digit morphogenesis
0.84	GO:0007224	smoothened signaling pathway
0.80	GO:0060271	cilium assembly
0.79	GO:0043010	camera-type eye development
0.78	GO:0001701	in utero embryonic development
0.78	GO:0001944	vasculature development
0.73	GO:0032880	regulation of protein localization
0.41	GO:0140056	organelle localization by membrane tethering

0.86

GO:0008158

hedgehog receptor activity

0.85	GO:0036038	MKS complex
0.82	GO:0036064	ciliary basal body
0.77	GO:0005813	centrosome
0.38	GO:0005829	cytosol
0.30	GO:0016020	membrane

tr|T1G781|T1G781_HELRO
Uncharacterized protein
Search

0.62	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.42	GO:0035094	response to nicotine
0.38	GO:0021771	lateral geniculate nucleus development
0.38	GO:0042320	regulation of circadian sleep/wake cycle, REM sleep
0.38	GO:0033603	positive regulation of dopamine secretion
0.38	GO:0060084	synaptic transmission involved in micturition
0.38	GO:0045188	regulation of circadian sleep/wake cycle, non-REM sleep
0.38	GO:0001661	conditioned taste aversion
0.38	GO:0045759	negative regulation of action potential

0.76	GO:0005230	extracellular ligand-gated ion channel activity
0.70	GO:0004888	transmembrane signaling receptor activity
0.64	GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential
0.61	GO:0022835	transmitter-gated channel activity
0.60	GO:0140135	mechanosensitive cation channel activity
0.38	GO:0042166	acetylcholine binding
0.33	GO:0030983	mismatched DNA binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.62	GO:0045211	postsynaptic membrane
0.59	GO:0030054	cell junction
0.42	GO:0005892	acetylcholine-gated channel complex
0.37	GO:0009897	external side of plasma membrane
0.33	GO:0032300	mismatch repair complex

tr|T1G782|T1G782_HELRO
Uncharacterized protein
Search

0.37	S-adenosyl-L-methionine-dependent methyltransferase

0.63	GO:0032259	methylation
0.40	GO:0006400	tRNA modification
0.35	GO:0044260	cellular macromolecule metabolic process
0.35	GO:0044026	DNA hypermethylation
0.35	GO:0002230	positive regulation of defense response to virus by host
0.35	GO:0001975	response to amphetamine
0.35	GO:0008340	determination of adult lifespan
0.34	GO:0045089	positive regulation of innate immune response
0.34	GO:0032200	telomere organization
0.34	GO:0016458	gene silencing

0.63	GO:0008168	methyltransferase activity
0.39	GO:0140101	catalytic activity, acting on a tRNA
0.35	GO:0004379	glycylpeptide N-tetradecanoyltransferase activity
0.34	GO:0005509	calcium ion binding
0.34	GO:0140097	catalytic activity, acting on DNA
0.34	GO:0005057	signal transducer activity, downstream of receptor
0.33	GO:0004674	protein serine/threonine kinase activity
0.33	GO:0003735	structural constituent of ribosome
0.33	GO:0003723	RNA binding
0.32	GO:0032559	adenyl ribonucleotide binding

0.35	GO:0016363	nuclear matrix
0.35	GO:0005737	cytoplasm
0.34	GO:0035770	ribonucleoprotein granule
0.30	GO:0016020	membrane

0.63

GO:0008168

tr|T1G783|T1G783_HELRO
Uncharacterized protein
Search

0.51	GO:0003676	nucleic acid binding
0.45	GO:0008270	zinc ion binding

0.44

GO:0005634

nucleus

tr|T1G784|T1G784_HELRO
Uncharacterized protein
Search

MARCH8

0.68	Membrane associated ring-CH-type finger 1

0.47	GO:0016567	protein ubiquitination
0.45	GO:0045347	negative regulation of MHC class II biosynthetic process
0.44	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II
0.37	GO:0002250	adaptive immune response
0.32	GO:0055114	oxidation-reduction process

0.63	GO:0008270	zinc ion binding
0.53	GO:0016874	ligase activity
0.47	GO:0004842	ubiquitin-protein transferase activity
0.44	GO:0042289	MHC class II protein binding
0.41	GO:0061659	ubiquitin-like protein ligase activity
0.33	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.33	GO:0020037	heme binding
0.33	GO:0005506	iron ion binding

0.47	GO:0005764	lysosome
0.46	GO:0005768	endosome
0.38	GO:0098852	lytic vacuole membrane
0.38	GO:0030659	cytoplasmic vesicle membrane
0.30	GO:0031224	intrinsic component of membrane

0.53	EC:6	GO:0016874
0.47	KEGG:R03876	GO:0004842

tr|T1G785|T1G785_HELRO
Uncharacterized protein
Search

0.47	Dynein regulatory complex subunit 3

0.46	GO:0045842	positive regulation of mitotic metaphase/anaphase transition
0.43	GO:0043666	regulation of phosphoprotein phosphatase activity
0.37	GO:0007165	signal transduction
0.37	GO:0000278	mitotic cell cycle
0.36	GO:0051301	cell division

0.47	GO:0072542	protein phosphatase activator activity
0.34	GO:0046872	metal ion binding

0.68	GO:0005930	axoneme
0.45	GO:0072357	PTW/PP1 phosphatase complex
0.42	GO:0019013	viral nucleocapsid
0.39	GO:0030529	intracellular ribonucleoprotein complex
0.39	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

tr|T1G786|T1G786_HELRO
Uncharacterized protein
Search

tr|T1G787|T1G787_HELRO
Uncharacterized protein
Search

0.53	Collagen (Fragment)

0.44	GO:0030198	extracellular matrix organization
0.42	GO:0071230	cellular response to amino acid stimulus
0.41	GO:1903225	negative regulation of endodermal cell differentiation
0.41	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.41	GO:0007275	multicellular organism development
0.40	GO:0009653	anatomical structure morphogenesis
0.39	GO:0007160	cell-matrix adhesion
0.38	GO:0097435	supramolecular fiber organization
0.38	GO:0052548	regulation of endopeptidase activity
0.37	GO:0010466	negative regulation of peptidase activity

0.72	GO:0005201	extracellular matrix structural constituent
0.40	GO:0046332	SMAD binding
0.39	GO:0008201	heparin binding
0.38	GO:0004867	serine-type endopeptidase inhibitor activity
0.36	GO:0042302	structural constituent of cuticle
0.35	GO:0005178	integrin binding
0.34	GO:0043394	proteoglycan binding
0.33	GO:0005509	calcium ion binding
0.33	GO:0048407	platelet-derived growth factor binding
0.33	GO:0002020	protease binding

0.67	GO:0005581	collagen trimer
0.60	GO:0044420	extracellular matrix component
0.57	GO:0005578	proteinaceous extracellular matrix
0.43	GO:0099081	supramolecular polymer
0.39	GO:0005615	extracellular space
0.34	GO:0005783	endoplasmic reticulum
0.34	GO:0031594	neuromuscular junction
0.33	GO:1903561	extracellular vesicle
0.33	GO:0070013	intracellular organelle lumen
0.32	GO:0042383	sarcolemma

0.32

GO:0004222

tr|T1G788|T1G788_HELRO
Uncharacterized protein
Search

0.53	GO:0006468	protein phosphorylation
0.45	GO:0048856	anatomical structure development
0.45	GO:0032501	multicellular organismal process
0.44	GO:0031034	myosin filament assembly
0.43	GO:0030154	cell differentiation
0.43	GO:0031032	actomyosin structure organization
0.42	GO:0035023	regulation of Rho protein signal transduction
0.41	GO:0007155	cell adhesion
0.41	GO:0097435	supramolecular fiber organization
0.40	GO:0070925	organelle assembly

0.53	GO:0004672	protein kinase activity
0.53	GO:0005509	calcium ion binding
0.47	GO:0030554	adenyl nucleotide binding
0.46	GO:0097367	carbohydrate derivative binding
0.46	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0008144	drug binding
0.44	GO:0097493	structural molecule activity conferring elasticity
0.44	GO:0051371	muscle alpha-actinin binding
0.43	GO:0008307	structural constituent of muscle
0.42	GO:0005089	Rho guanyl-nucleotide exchange factor activity

0.44	GO:0031430	M band
0.44	GO:0005859	muscle myosin complex
0.43	GO:0030018	Z disc
0.43	GO:0005604	basement membrane
0.37	GO:0005938	cell cortex
0.37	GO:0030054	cell junction
0.37	GO:0030673	axolemma
0.36	GO:0005865	striated muscle thin filament
0.36	GO:0070062	extracellular exosome
0.36	GO:0000794	condensed nuclear chromosome

0.37	EC:1.11.1.7	GO:0004601
0.37	KEGG:R03532	GO:0004601

tr|T1G789|T1G789_HELRO
Uncharacterized protein
Search

0.10	Hemicentin 1

0.48	GO:0006030	chitin metabolic process
0.44	GO:0030198	extracellular matrix organization
0.41	GO:0033334	fin morphogenesis
0.40	GO:0007166	cell surface receptor signaling pathway
0.40	GO:0007155	cell adhesion
0.37	GO:0048518	positive regulation of biological process
0.37	GO:0007186	G-protein coupled receptor signaling pathway
0.36	GO:0006508	proteolysis
0.36	GO:0030162	regulation of proteolysis
0.36	GO:0051345	positive regulation of hydrolase activity

0.65	GO:0005509	calcium ion binding
0.48	GO:0008061	chitin binding
0.42	GO:0005201	extracellular matrix structural constituent
0.40	GO:0005042	netrin receptor activity
0.37	GO:0004930	G-protein coupled receptor activity
0.37	GO:0016504	peptidase activator activity
0.37	GO:0004222	metalloendopeptidase activity
0.36	GO:0008201	heparin binding
0.36	GO:0038191	neuropilin binding
0.34	GO:0004252	serine-type endopeptidase activity

0.49	GO:0005576	extracellular region
0.36	GO:0005938	cell cortex
0.36	GO:0030054	cell junction
0.34	GO:0005579	membrane attack complex
0.34	GO:0009986	cell surface
0.34	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0032155	cell division site part
0.33	GO:0005634	nucleus
0.33	GO:0098552	side of membrane
0.32	GO:0099512	supramolecular fiber

0.37

GO:0004222

tr|T1G790|T1G790_HELRO
Uncharacterized protein
Search

0.65	FERM domain containing 5

0.46	GO:2000146	negative regulation of cell motility
0.45	GO:0030334	regulation of cell migration
0.44	GO:0045785	positive regulation of cell adhesion
0.44	GO:0031032	actomyosin structure organization

0.62	GO:0008092	cytoskeletal protein binding
0.47	GO:0005178	integrin binding
0.45	GO:0019901	protein kinase binding
0.43	GO:0005200	structural constituent of cytoskeleton

0.69	GO:0005856	cytoskeleton
0.45	GO:0005912	adherens junction
0.30	GO:0044425	membrane part

tr|T1G791|T1G791_HELRO
Uncharacterized protein
Search

0.85	GO:0097359	UDP-glucosylation
0.74	GO:0006486	protein glycosylation
0.46	GO:0071712	ER-associated misfolded protein catabolic process
0.45	GO:0018196	peptidyl-asparagine modification
0.45	GO:0030968	endoplasmic reticulum unfolded protein response
0.45	GO:0051084	'de novo' posttranslational protein folding
0.32	GO:0016310	phosphorylation

0.85	GO:0003980	UDP-glucose:glycoprotein glucosyltransferase activity
0.42	GO:0051082	unfolded protein binding
0.32	GO:0016301	kinase activity
0.32	GO:0003676	nucleic acid binding

0.41	GO:0005783	endoplasmic reticulum
0.40	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.85

GO:0003980

tr|T1G792|T1G792_HELRO
Uncharacterized protein
Search

ACAT1

0.38	Fatty alcohol acetyltransferase

0.39	GO:0006635	fatty acid beta-oxidation
0.33	GO:0045454	cell redox homeostasis
0.33	GO:0033014	tetrapyrrole biosynthetic process
0.33	GO:0022900	electron transport chain

0.64	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
0.34	GO:0015035	protein disulfide oxidoreductase activity
0.33	GO:0070279	vitamin B6 binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.33	GO:0009055	electron transfer activity
0.33	GO:0050662	coenzyme binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.36

GO:0005739

mitochondrion

0.64

EC:2.3.1

GO:0016747

tr|T1G793|T1G793_HELRO
Uncharacterized protein
Search

tr|T1G794|T1G794_HELRO
Uncharacterized protein
Search

0.56	Calcium-binding mitochondrial carrier protein SCaMC-2-A

0.55	GO:0055085	transmembrane transport
0.41	GO:0015867	ATP transport
0.40	GO:0015866	ADP transport
0.40	GO:0006839	mitochondrial transport
0.37	GO:0071277	cellular response to calcium ion
0.36	GO:0034599	cellular response to oxidative stress
0.36	GO:0010941	regulation of cell death
0.35	GO:0032094	response to food
0.35	GO:0002021	response to dietary excess
0.35	GO:0014823	response to activity

0.61	GO:0005509	calcium ion binding
0.42	GO:0005347	ATP transmembrane transporter activity
0.40	GO:0015217	ADP transmembrane transporter activity
0.35	GO:0016746	transferase activity, transferring acyl groups
0.35	GO:0003723	RNA binding
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.33	GO:0043565	sequence-specific DNA binding
0.33	GO:0008270	zinc ion binding
0.32	GO:0003700	DNA binding transcription factor activity

0.53	GO:0031966	mitochondrial membrane
0.53	GO:0019866	organelle inner membrane
0.32	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:2.3

GO:0016746

tr|T1G795|T1G795_HELRO
Uncharacterized protein
Search

LRRC6

0.70	Leucine rich repeat containing 6

0.87	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry
0.86	GO:0036158	outer dynein arm assembly
0.85	GO:0036159	inner dynein arm assembly
0.85	GO:0044458	motile cilium assembly
0.85	GO:0030317	flagellated sperm motility
0.85	GO:0008584	male gonad development

0.77	GO:0005929	cilium
0.49	GO:0005737	cytoplasm

tr|T1G796|T1G796_HELRO
Uncharacterized protein
Search

0.70	Nicotinic acetylcholine receptor subunit alpha 5 mRNA transcript variant 1

0.73	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.42	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound
0.41	GO:0042472	inner ear morphogenesis
0.41	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.40	GO:0006812	cation transport
0.35	GO:0035094	response to nicotine
0.35	GO:0007271	synaptic transmission, cholinergic
0.34	GO:0007274	neuromuscular synaptic transmission
0.33	GO:0006278	RNA-dependent DNA biosynthetic process

0.76	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0099600	transmembrane receptor activity
0.45	GO:0022850	serotonin-gated cation-selective channel activity
0.35	GO:0008146	sulfotransferase activity
0.35	GO:0042166	acetylcholine binding
0.34	GO:0005262	calcium channel activity
0.34	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.34	GO:0005515	protein binding
0.33	GO:0046872	metal ion binding
0.33	GO:0003964	RNA-directed DNA polymerase activity

0.72	GO:0045211	postsynaptic membrane
0.68	GO:0030054	cell junction
0.42	GO:0005892	acetylcholine-gated channel complex

0.35

EC:2.8.2

GO:0008146

tr|T1G797|T1G797_HELRO
Uncharacterized protein
Search

0.48	GO:0045925	positive regulation of female receptivity
0.46	GO:0016319	mushroom body development
0.45	GO:0008344	adult locomotory behavior
0.43	GO:0031175	neuron projection development
0.34	GO:0006869	lipid transport
0.34	GO:0048387	negative regulation of retinoic acid receptor signaling pathway
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression
0.33	GO:0045665	negative regulation of neuron differentiation

0.51	GO:0003676	nucleic acid binding
0.34	GO:0005319	lipid transporter activity
0.34	GO:0046872	metal ion binding
0.33	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.32	GO:0016491	oxidoreductase activity

0.34	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.32

GO:0016491

tr|T1G798|T1G798_HELRO
Uncharacterized protein
Search

tr|T1G799|T1G799_HELRO
Cation-transporting ATPase
Search

ATP13A2

0.63	Cation-transporting ATPase

0.60	GO:0006812	cation transport
0.40	GO:0007626	locomotory behavior
0.40	GO:0006874	cellular calcium ion homeostasis
0.40	GO:0043009	chordate embryonic development
0.38	GO:0099131	ATP hydrolysis coupled ion transmembrane transport
0.37	GO:0098660	inorganic ion transmembrane transport
0.35	GO:1905165	regulation of lysosomal protein catabolic process
0.35	GO:1901215	negative regulation of neuron death
0.34	GO:0052548	regulation of endopeptidase activity
0.34	GO:0015074	DNA integration

0.60	GO:0016887	ATPase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0046872	metal ion binding
0.40	GO:0015085	calcium ion transmembrane transporter activity
0.38	GO:0022853	active ion transmembrane transporter activity
0.37	GO:0015399	primary active transmembrane transporter activity
0.32	GO:0003676	nucleic acid binding

0.38	GO:0005887	integral component of plasma membrane
0.36	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0098805	whole membrane
0.34	GO:0098588	bounding membrane of organelle
0.33	GO:0044446	intracellular organelle part
0.32	GO:0044444	cytoplasmic part

0.60

GO:0016887

tr|T1G7A0|T1G7A0_HELRO
Uncharacterized protein
Search

0.39	Catechol-O-methyltransferase domain-containing protein 1

0.63	GO:0032259	methylation
0.33	GO:0015031	protein transport
0.33	GO:0006357	regulation of transcription by RNA polymerase II
0.32	GO:0006351	transcription, DNA-templated

0.73	GO:0008171	O-methyltransferase activity
0.37	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity
0.33	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.32	GO:0008270	zinc ion binding
0.32	GO:0003677	DNA binding

0.36	GO:0005739	mitochondrion
0.33	GO:0005829	cytosol
0.32	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.73

GO:0008171

tr|T1G7A1|T1G7A1_HELRO
Mitogen-activated protein kinase
Search

0.59	Stress-activated protein kinase JNK

0.80	GO:0000165	MAPK cascade
0.47	GO:0031098	stress-activated protein kinase signaling cascade
0.47	GO:1903688	positive regulation of border follicle cell migration
0.46	GO:1904801	positive regulation of neuron remodeling
0.46	GO:0048674	collateral sprouting of injured axon
0.46	GO:0048615	embryonic anterior midgut (ectodermal) morphogenesis
0.46	GO:0046844	micropyle formation
0.46	GO:0007395	dorsal closure, spreading of leading edge cells
0.45	GO:0048803	imaginal disc-derived male genitalia morphogenesis
0.45	GO:0046528	imaginal disc fusion

0.82	GO:0004707	MAP kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.35	GO:0005515	protein binding
0.32	GO:0046872	metal ion binding

0.45	GO:0005622	intracellular
0.45	GO:0043005	neuron projection
0.43	GO:0036477	somatodendritic compartment
0.41	GO:0120038	plasma membrane bounded cell projection part
0.36	GO:0043227	membrane-bounded organelle
0.35	GO:0044297	cell body
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0044422	organelle part

0.82	EC:2.7.11.24	GO:0004707
0.82	KEGG:R00162	GO:0004707

tr|T1G7A2|T1G7A2_HELRO
Uncharacterized protein
Search

tr|T1G7A3|T1G7A3_HELRO
Uncharacterized protein
Search

0.55	FERM, RhoGEF and pleckstrin domain-containing protein 2

0.74	GO:0035023	regulation of Rho protein signal transduction
0.64	GO:0065009	regulation of molecular function
0.44	GO:0033623	regulation of integrin activation
0.44	GO:0071800	podosome assembly
0.44	GO:0016601	Rac protein signal transduction
0.43	GO:0016322	neuron remodeling
0.43	GO:0030316	osteoclast differentiation
0.42	GO:0071526	semaphorin-plexin signaling pathway
0.41	GO:0031532	actin cytoskeleton reorganization
0.40	GO:0007155	cell adhesion

0.75	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.60	GO:0008092	cytoskeletal protein binding
0.44	GO:0048365	Rac GTPase binding

0.64	GO:0005856	cytoskeleton
0.36	GO:0030425	dendrite
0.36	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.36	GO:0005829	cytosol
0.35	GO:0044309	neuron spine
0.35	GO:0030175	filopodium
0.34	GO:0098794	postsynapse
0.34	GO:0030054	cell junction
0.30	GO:0016021	integral component of membrane

tr|T1G7A4|T1G7A4_HELRO
Uncharacterized protein
Search

ORC4

0.50	Origin recognition complex subunit 4

0.51	GO:0006260	DNA replication
0.45	GO:0030466	chromatin silencing at silent mating-type cassette
0.43	GO:0065004	protein-DNA complex assembly
0.41	GO:0022402	cell cycle process
0.32	GO:0009435	NAD biosynthetic process
0.32	GO:0006518	peptide metabolic process
0.32	GO:0043604	amide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0055085	transmembrane transport
0.32	GO:0010467	gene expression

0.46	GO:0003688	DNA replication origin binding
0.45	GO:0046872	metal ion binding
0.36	GO:0000166	nucleotide binding
0.35	GO:0097367	carbohydrate derivative binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003735	structural constituent of ribosome
0.32	GO:0005515	protein binding
0.32	GO:0016779	nucleotidyltransferase activity
0.32	GO:0016787	hydrolase activity

0.60	GO:0000808	origin recognition complex
0.48	GO:0005634	nucleus
0.46	GO:0036387	pre-replicative complex
0.43	GO:0031974	membrane-enclosed lumen
0.40	GO:0000781	chromosome, telomeric region
0.38	GO:0005829	cytosol
0.33	GO:0000785	chromatin
0.32	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

0.32

EC:2.7.7

GO:0016779

tr|T1G7A5|T1G7A5_HELRO
Uncharacterized protein
Search

0.63	N-acetyllactosaminide 3-alpha-galactosyltransferase

0.60	GO:0005975	carbohydrate metabolic process
0.39	GO:0007626	locomotory behavior
0.38	GO:0021680	cerebellar Purkinje cell layer development
0.38	GO:0008542	visual learning
0.37	GO:0007613	memory
0.37	GO:0006688	glycosphingolipid biosynthetic process
0.37	GO:0007528	neuromuscular junction development
0.36	GO:0030534	adult behavior
0.36	GO:0006044	N-acetylglucosamine metabolic process
0.35	GO:0043413	macromolecule glycosylation

0.65	GO:0016757	transferase activity, transferring glycosyl groups
0.36	GO:0140103	catalytic activity, acting on a glycoprotein
0.33	GO:0030145	manganese ion binding
0.33	GO:0008092	cytoskeletal protein binding
0.32	GO:0008134	transcription factor binding
0.32	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.32	GO:0001882	nucleoside binding
0.32	GO:0003677	DNA binding

0.38	GO:0005794	Golgi apparatus
0.36	GO:0005654	nucleoplasm
0.35	GO:0005911	cell-cell junction
0.35	GO:0031984	organelle subcompartment
0.34	GO:0031526	brush border membrane
0.34	GO:0098588	bounding membrane of organelle
0.34	GO:0016323	basolateral plasma membrane
0.34	GO:0009897	external side of plasma membrane
0.34	GO:0070161	anchoring junction
0.33	GO:0098797	plasma membrane protein complex

0.65

GO:0016757

tr|T1G7A6|T1G7A6_HELRO
Uncharacterized protein
Search

MAN2A1

0.73	Alpha-mannosidase 2

0.81	GO:0006013	mannose metabolic process
0.49	GO:0006491	N-glycan processing
0.47	GO:0006517	protein deglycosylation
0.44	GO:0007585	respiratory gaseous exchange
0.44	GO:0048286	lung alveolus development
0.43	GO:0060042	retina morphogenesis in camera-type eye
0.43	GO:0001889	liver development
0.42	GO:0050769	positive regulation of neurogenesis
0.42	GO:0007033	vacuole organization
0.41	GO:0007005	mitochondrion organization

0.79	GO:0004559	alpha-mannosidase activity
0.69	GO:0030246	carbohydrate binding
0.52	GO:0046872	metal ion binding
0.40	GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds
0.34	GO:0004970	ionotropic glutamate receptor activity
0.33	GO:0004471	malate dehydrogenase (decarboxylating) (NAD+) activity
0.33	GO:0005047	signal recognition particle binding
0.33	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.33	GO:0051287	NAD binding
0.33	GO:0016758	transferase activity, transferring hexosyl groups

0.46	GO:0098791	Golgi subcompartment
0.44	GO:0098588	bounding membrane of organelle
0.43	GO:0005801	cis-Golgi network
0.40	GO:0005615	extracellular space
0.37	GO:0005768	endosome
0.34	GO:0005783	endoplasmic reticulum
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.32	GO:0098796	membrane protein complex
0.30	GO:0016021	integral component of membrane

0.79	EC:3.2.1.24	GO:0004559
0.33	KEGG:R00214	GO:0004471

tr|T1G7A7|T1G7A7_HELRO
Uncharacterized protein
Search

0.78	Short coiled-coil protein (inferred by orthology to a human protein)

0.70	GO:0030516	regulation of axon extension
0.68	GO:0050807	regulation of synapse organization
0.53	GO:0061635	regulation of protein complex stability
0.51	GO:0016239	positive regulation of macroautophagy
0.40	GO:0006518	peptide metabolic process
0.39	GO:0043604	amide biosynthetic process
0.38	GO:0044267	cellular protein metabolic process
0.38	GO:1901566	organonitrogen compound biosynthetic process
0.38	GO:0010467	gene expression
0.37	GO:0009059	macromolecule biosynthetic process

0.46	GO:0003779	actin binding
0.41	GO:0003735	structural constituent of ribosome

0.67	GO:0043025	neuronal cell body
0.66	GO:0030424	axon
0.65	GO:0048471	perinuclear region of cytoplasm
0.53	GO:0000139	Golgi membrane
0.50	GO:0005829	cytosol
0.43	GO:0015934	large ribosomal subunit
0.30	GO:0031224	intrinsic component of membrane

tr|T1G7A8|T1G7A8_HELRO
Uncharacterized protein
Search

0.12	Putative 52 kDa repressor of the inhibitor of the protein kinase (Fragment)

0.57

GO:0016310

phosphorylation

0.68	GO:0046983	protein dimerization activity
0.60	GO:0016301	kinase activity
0.36	GO:0003676	nucleic acid binding

tr|T1G7A9|T1G7A9_HELRO
Uncharacterized protein
Search

0.68	GO:0071804	cellular potassium ion transport
0.58	GO:0098662	inorganic cation transmembrane transport
0.46	GO:0030322	stabilization of membrane potential
0.35	GO:0034765	regulation of ion transmembrane transport
0.34	GO:0061337	cardiac conduction
0.32	GO:0007018	microtubule-based movement

0.70	GO:0005267	potassium channel activity
0.46	GO:0022842	narrow pore channel activity
0.34	GO:0022832	voltage-gated channel activity
0.34	GO:0022839	ion gated channel activity
0.34	GO:0008381	mechanosensitive ion channel activity
0.32	GO:0003777	microtubule motor activity
0.32	GO:0008017	microtubule binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.40

GO:0005887

integral component of plasma membrane

tr|T1G7B0|T1G7B0_HELRO
Uncharacterized protein
Search

tr|T1G7B1|T1G7B1_HELRO
Uncharacterized protein
Search

tr|T1G7B2|T1G7B2_HELRO
Uncharacterized protein
Search

0.78	GO:0043401	steroid hormone mediated signaling pathway
0.77	GO:0030522	intracellular receptor signaling pathway
0.58	GO:0097659	nucleic acid-templated transcription
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0010467	gene expression
0.53	GO:0034645	cellular macromolecule biosynthetic process
0.47	GO:0071376	cellular response to corticotropin-releasing hormone stimulus
0.46	GO:0051866	general adaptation syndrome

0.79	GO:0003707	steroid hormone receptor activity
0.79	GO:0004879	nuclear receptor activity
0.65	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.46	GO:0001012	RNA polymerase II regulatory region DNA binding
0.46	GO:0046982	protein heterodimerization activity
0.45	GO:0035259	glucocorticoid receptor binding
0.44	GO:0003690	double-stranded DNA binding
0.44	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.43	GO:0001047	core promoter binding

0.61	GO:0005634	nucleus
0.40	GO:0070013	intracellular organelle lumen
0.38	GO:0044446	intracellular organelle part
0.36	GO:0005737	cytoplasm
0.33	GO:0005667	transcription factor complex
0.33	GO:1990204	oxidoreductase complex
0.33	GO:0012505	endomembrane system
0.32	GO:0031090	organelle membrane
0.32	GO:0031975	envelope

0.34

EC:1.1.5.3

GO:0052590

tr|T1G7B3|T1G7B3_HELRO
Uncharacterized protein
Search

tr|T1G7B4|T1G7B4_HELRO
Uncharacterized protein
Search

BROX

0.60	BRO1 domain and CAAX motif containing

tr|T1G7B5|T1G7B5_HELRO
Uncharacterized protein
Search

0.73	GO:0007224	smoothened signaling pathway
0.38	GO:0007225	patched ligand maturation
0.38	GO:0060539	diaphragm development
0.37	GO:0007280	pole cell migration
0.36	GO:0009880	embryonic pattern specification
0.36	GO:0007368	determination of left/right symmetry
0.36	GO:0009953	dorsal/ventral pattern formation
0.34	GO:0042886	amide transport
0.34	GO:0071702	organic substance transport
0.33	GO:1905515	non-motile cilium assembly

0.41	GO:0008270	zinc ion binding
0.39	GO:0016874	ligase activity
0.35	GO:0015197	peptide transporter activity

0.35	GO:0005622	intracellular
0.33	GO:0034464	BBSome
0.30	GO:0016020	membrane

0.39

GO:0016874

tr|T1G7B6|T1G7B6_HELRO
Sodium channel protein
Search

SCN11A

0.53	Sodium channel protein type 4 subunit alpha A

0.77	GO:0035725	sodium ion transmembrane transport
0.74	GO:0034765	regulation of ion transmembrane transport
0.51	GO:0019233	sensory perception of pain
0.51	GO:0051930	regulation of sensory perception of pain
0.47	GO:0019228	neuronal action potential
0.47	GO:0086010	membrane depolarization during action potential
0.35	GO:0001947	heart looping
0.34	GO:0008016	regulation of heart contraction
0.34	GO:0042493	response to drug
0.33	GO:0071804	cellular potassium ion transport

0.84	GO:0005248	voltage-gated sodium channel activity
0.72	GO:0022832	voltage-gated channel activity
0.70	GO:0022839	ion gated channel activity
0.69	GO:0008381	mechanosensitive ion channel activity
0.48	GO:0005509	calcium ion binding
0.34	GO:0005515	protein binding
0.33	GO:0005267	potassium channel activity

0.83	GO:0001518	voltage-gated sodium channel complex
0.53	GO:0044299	C-fiber
0.36	GO:0070062	extracellular exosome
0.33	GO:0008076	voltage-gated potassium channel complex

tr|T1G7B7|T1G7B7_HELRO
Uncharacterized protein
Search

0.72	GO:0006898	receptor-mediated endocytosis
0.41	GO:0002040	sprouting angiogenesis
0.39	GO:0018057	peptidyl-lysine oxidation
0.39	GO:1902455	negative regulation of stem cell population maintenance
0.38	GO:0032332	positive regulation of chondrocyte differentiation
0.38	GO:0006508	proteolysis
0.38	GO:0001935	endothelial cell proliferation
0.38	GO:0010718	positive regulation of epithelial to mesenchymal transition
0.38	GO:0030199	collagen fibril organization
0.38	GO:0070828	heterochromatin organization

0.81	GO:0005044	scavenger receptor activity
0.43	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor
0.42	GO:0005507	copper ion binding
0.39	GO:0004252	serine-type endopeptidase activity
0.38	GO:0070492	oligosaccharide binding
0.37	GO:0001871	pattern binding
0.35	GO:0005509	calcium ion binding
0.34	GO:0004197	cysteine-type endopeptidase activity
0.33	GO:0004222	metalloendopeptidase activity
0.33	GO:0008270	zinc ion binding

0.39	GO:0009897	external side of plasma membrane
0.37	GO:0005576	extracellular region
0.36	GO:0000785	chromatin
0.36	GO:0005737	cytoplasm
0.36	GO:0005654	nucleoplasm
0.35	GO:0012505	endomembrane system
0.30	GO:0016021	integral component of membrane

0.43

EC:1.4.3

GO:0016641

tr|T1G7B8|T1G7B8_HELRO
Uncharacterized protein
Search

PXDN

0.89	Peroxidasin like

0.71	GO:0006979	response to oxidative stress
0.69	GO:0098869	cellular oxidant detoxification
0.54	GO:0030198	extracellular matrix organization
0.53	GO:0055114	oxidation-reduction process
0.49	GO:0042744	hydrogen peroxide catabolic process
0.39	GO:0022607	cellular component assembly
0.35	GO:0048585	negative regulation of response to stimulus
0.34	GO:0001959	regulation of cytokine-mediated signaling pathway
0.34	GO:0006955	immune response
0.34	GO:0048523	negative regulation of cellular process

0.72	GO:0004601	peroxidase activity
0.63	GO:0020037	heme binding
0.51	GO:0005201	extracellular matrix structural constituent
0.36	GO:0005152	interleukin-1 receptor antagonist activity
0.34	GO:0046872	metal ion binding

0.50	GO:0005615	extracellular space
0.48	GO:0031012	extracellular matrix
0.46	GO:0005783	endoplasmic reticulum
0.36	GO:1903561	extracellular vesicle

0.72	EC:1.11.1.7	GO:0004601
0.72	KEGG:R03532	GO:0004601

tr|T1G7C0|T1G7C0_HELRO
Uncharacterized protein
Search

0.51	Class 2 transcription repressor NC2

0.37	GO:0000122	negative regulation of transcription by RNA polymerase II
0.35	GO:0032774	RNA biosynthetic process
0.34	GO:0010467	gene expression
0.34	GO:0034645	cellular macromolecule biosynthetic process

0.74	GO:0046982	protein heterodimerization activity
0.46	GO:0042802	identical protein binding
0.37	GO:0003714	transcription corepressor activity
0.35	GO:0008134	transcription factor binding
0.35	GO:0003677	DNA binding
0.34	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.33	GO:0003700	DNA binding transcription factor activity

0.58	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.34

GO:0003899

tr|T1G7C1|T1G7C1_HELRO
Uncharacterized protein
Search

tr|T1G7C2|T1G7C2_HELRO
Superoxide dismutase
Search

0.46	Mn-superoxide dismutase

0.75	GO:0071450	cellular response to oxygen radical
0.75	GO:0000303	response to superoxide
0.75	GO:0006801	superoxide metabolic process
0.69	GO:0098869	cellular oxidant detoxification
0.52	GO:0055114	oxidation-reduction process
0.39	GO:0051597	response to methylmercury
0.39	GO:0001780	neutrophil homeostasis
0.38	GO:0046686	response to cadmium ion
0.37	GO:0045087	innate immune response
0.35	GO:0038001	paracrine signaling

0.77	GO:0004784	superoxide dismutase activity
0.54	GO:0046872	metal ion binding
0.37	GO:0042803	protein homodimerization activity

0.39	GO:0097249	mitochondrial respiratory chain supercomplex
0.36	GO:0005759	mitochondrial matrix

0.77

EC:1.15.1.1

GO:0004784

tr|T1G7C3|T1G7C3_HELRO
Uncharacterized protein
Search

MKNK1

0.76	MAP kinase-interacting serine/threonine-protein kinase 2

0.63	GO:0006468	protein phosphorylation
0.43	GO:0005978	glycogen biosynthetic process
0.42	GO:0018209	peptidyl-serine modification
0.42	GO:0071243	cellular response to arsenic-containing substance
0.41	GO:0038034	signal transduction in absence of ligand
0.40	GO:0097191	extrinsic apoptotic signaling pathway
0.40	GO:0035556	intracellular signal transduction
0.40	GO:0030097	hemopoiesis
0.36	GO:0035095	behavioral response to nicotine
0.36	GO:0018210	peptidyl-threonine modification

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0005516	calmodulin binding
0.42	GO:0005509	calcium ion binding
0.35	GO:0000287	magnesium ion binding
0.33	GO:0004003	ATP-dependent DNA helicase activity
0.33	GO:0019901	protein kinase binding
0.32	GO:0009982	pseudouridine synthase activity

0.46	GO:0005964	phosphorylase kinase complex
0.40	GO:0016604	nuclear body
0.33	GO:0005829	cytosol
0.33	GO:0099512	supramolecular fiber
0.33	GO:0031616	spindle pole centrosome
0.33	GO:0032133	chromosome passenger complex
0.33	GO:0051233	spindle midzone
0.33	GO:0000780	condensed nuclear chromosome, centromeric region
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.32

EC:5.4.99.12

GO:0009982

tr|T1G7C4|T1G7C4_HELRO
Uncharacterized protein
Search

tr|T1G7C5|T1G7C5_HELRO
Uncharacterized protein
Search

0.93	3 beta-hydroxysteroid dehydrogenase type

0.73	GO:0006694	steroid biosynthetic process
0.51	GO:0055114	oxidation-reduction process
0.33	GO:0005975	carbohydrate metabolic process
0.33	GO:0043043	peptide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process

0.78	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity
0.47	GO:0016853	isomerase activity
0.43	GO:0050662	coenzyme binding
0.36	GO:0045552	dihydrokaempferol 4-reductase activity
0.33	GO:0003735	structural constituent of ribosome

0.33	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

0.78

EC:1.1.1.145

GO:0003854

tr|T1G7C6|T1G7C6_HELRO
Uncharacterized protein
Search

SLC2A8

0.57	Solute carrier family 2, facilitated glucose transporter member

0.56	GO:0008643	carbohydrate transport
0.55	GO:0055085	transmembrane transport
0.39	GO:0008286	insulin receptor signaling pathway
0.38	GO:0001666	response to hypoxia
0.38	GO:0007141	male meiosis I
0.37	GO:0015992	proton transport
0.35	GO:0006006	glucose metabolic process
0.32	GO:0055114	oxidation-reduction process

0.57	GO:0022857	transmembrane transporter activity
0.38	GO:0005536	glucose binding
0.32	GO:0016491	oxidoreductase activity

0.37	GO:0008021	synaptic vesicle
0.36	GO:0030659	cytoplasmic vesicle membrane
0.36	GO:0005887	integral component of plasma membrane
0.35	GO:0005765	lysosomal membrane

0.32

GO:0016491

tr|T1G7C7|T1G7C7_HELRO
Uncharacterized protein
Search

0.78	Egl-1 suppressor/dio uptake defective/raf enhancer family member eor-1

0.82	GO:0030837	negative regulation of actin filament polymerization
0.42	GO:0030042	actin filament depolymerization
0.40	GO:0008407	chaeta morphogenesis
0.40	GO:0010591	regulation of lamellipodium assembly
0.40	GO:0016319	mushroom body development
0.40	GO:0048488	synaptic vesicle endocytosis
0.40	GO:0007274	neuromuscular synaptic transmission
0.40	GO:0007298	border follicle cell migration
0.38	GO:0044396	actin cortical patch organization
0.38	GO:0030836	positive regulation of actin filament depolymerization

0.74	GO:0003779	actin binding
0.36	GO:0032403	protein complex binding

0.45	GO:0005622	intracellular
0.38	GO:0045202	synapse
0.37	GO:0043228	non-membrane-bounded organelle
0.36	GO:0099512	supramolecular fiber
0.35	GO:0005886	plasma membrane
0.34	GO:0044422	organelle part
0.30	GO:0016021	integral component of membrane

tr|T1G7C8|T1G7C8_HELRO
Uncharacterized protein
Search

DPM1

0.51	Dolichol-phosphate mannosyltransferase dolichol-phosphate mannose synthase dolichyl-phosphate beta-d-mannosyltransferase mannose-p-dolichol synthase mpd synthase dpm synthase

0.43	GO:0097502	mannosylation
0.42	GO:0061061	muscle structure development
0.42	GO:0006506	GPI anchor biosynthetic process
0.41	GO:0006493	protein O-linked glycosylation
0.40	GO:0019348	dolichol metabolic process
0.35	GO:0018279	protein N-linked glycosylation via asparagine
0.35	GO:0019673	GDP-mannose metabolic process
0.34	GO:0015992	proton transport
0.33	GO:0055085	transmembrane transport

0.63	GO:0016757	transferase activity, transferring glycosyl groups
0.36	GO:0005537	mannose binding
0.35	GO:0043178	alcohol binding
0.35	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.33	GO:0005515	protein binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.40	GO:0005783	endoplasmic reticulum
0.40	GO:0033185	dolichol-phosphate-mannose synthase complex
0.40	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.39	GO:0031984	organelle subcompartment
0.37	GO:0016471	vacuolar proton-transporting V-type ATPase complex
0.34	GO:0005634	nucleus

0.63

GO:0016757

tr|T1G7C9|T1G7C9_HELRO
Uncharacterized protein
Search

0.58	Hepatoma-derived growth factor-related protein 2

0.77	GO:0030307	positive regulation of cell growth
0.40	GO:0007026	negative regulation of microtubule depolymerization
0.39	GO:0046785	microtubule polymerization
0.38	GO:0031175	neuron projection development
0.36	GO:0006418	tRNA aminoacylation for protein translation

0.43	GO:0003682	chromatin binding
0.41	GO:0005515	protein binding
0.37	GO:0003677	DNA binding
0.36	GO:0016875	ligase activity, forming carbon-oxygen bonds
0.36	GO:0140101	catalytic activity, acting on a tRNA
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.44	GO:0005634	nucleus
0.37	GO:0005829	cytosol
0.37	GO:0043233	organelle lumen
0.36	GO:0005576	extracellular region
0.35	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.36

EC:6.1

GO:0016875

tr|T1G7D0|T1G7D0_HELRO
Uncharacterized protein
Search

0.54	GO:0055085	transmembrane transport
0.40	GO:0007390	germ-band shortening
0.39	GO:0015711	organic anion transport
0.39	GO:0040018	positive regulation of multicellular organism growth
0.39	GO:0015879	carnitine transport
0.39	GO:0030307	positive regulation of cell growth
0.37	GO:0070715	sodium-dependent organic cation transport
0.37	GO:0060731	positive regulation of intestinal epithelial structure maintenance
0.37	GO:0015698	inorganic anion transport
0.37	GO:0052097	interspecies quorum sensing

0.55	GO:0022857	transmembrane transporter activity
0.36	GO:0030165	PDZ domain binding
0.35	GO:0032440	2-alkenal reductase [NAD(P)] activity

0.39	GO:0005887	integral component of plasma membrane
0.37	GO:0098590	plasma membrane region
0.36	GO:0005903	brush border
0.35	GO:0045177	apical part of cell
0.35	GO:0120038	plasma membrane bounded cell projection part

0.35

GO:0032440

tr|T1G7D1|T1G7D1_HELRO
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial
Search

UBIE

0.49	Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE

0.71	GO:1901663	quinone biosynthetic process
0.71	GO:0006743	ubiquinone metabolic process
0.69	GO:0009233	menaquinone metabolic process
0.63	GO:0032259	methylation
0.58	GO:0009060	aerobic respiration
0.33	GO:0032392	DNA geometric change
0.32	GO:1901360	organic cyclic compound metabolic process
0.32	GO:0046483	heterocycle metabolic process
0.32	GO:0006725	cellular aromatic compound metabolic process
0.32	GO:0034641	cellular nitrogen compound metabolic process

0.77	GO:0102005	2-octaprenyl-6-methoxy-1,4-benzoquinone methylase activity
0.77	GO:0008425	2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity
0.71	GO:0102955	S-adenosylmethionine:2-demethylmenaquinol-7 methyltransferase activity
0.33	GO:0004003	ATP-dependent DNA helicase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0003677	DNA binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.53	GO:0031314	extrinsic component of mitochondrial inner membrane
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.77

EC:2.1.1.201

GO:0102005

tr|T1G7D2|T1G7D2_HELRO
Uncharacterized protein
Search

0.66	TATA box binding protein tbp-associated factor

0.76	GO:0006366	transcription by RNA polymerase II
0.59	GO:0006413	translational initiation
0.42	GO:0009960	endosperm development
0.42	GO:0071805	potassium ion transmembrane transport
0.41	GO:0048278	vesicle docking
0.41	GO:0006887	exocytosis
0.40	GO:0009793	embryo development ending in seed dormancy
0.38	GO:0006357	regulation of transcription by RNA polymerase II

0.74	GO:0046982	protein heterodimerization activity
0.60	GO:0003743	translation initiation factor activity
0.43	GO:0005267	potassium channel activity
0.39	GO:0003712	transcription cofactor activity
0.38	GO:0008022	protein C-terminus binding
0.36	GO:0003677	DNA binding

0.41	GO:0005669	transcription factor TFIID complex
0.41	GO:0000145	exocyst
0.36	GO:0005730	nucleolus
0.30	GO:0016020	membrane

tr|T1G7D3|T1G7D3_HELRO
Uncharacterized protein
Search

tr|T1G7D4|T1G7D4_HELRO
Uncharacterized protein
Search

0.37	Serine and arginine rich splicing factor 3

0.38	GO:1990823	response to leukemia inhibitory factor
0.38	GO:0048024	regulation of mRNA splicing, via spliceosome
0.37	GO:0071345	cellular response to cytokine stimulus
0.34	GO:0007050	cell cycle arrest
0.34	GO:0071901	negative regulation of protein serine/threonine kinase activity

0.59	GO:0003723	RNA binding
0.51	GO:0008270	zinc ion binding
0.39	GO:0043274	phospholipase binding
0.34	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.38	GO:0016607	nuclear speck
0.33	GO:0005576	extracellular region
0.30	GO:0016020	membrane

tr|T1G7D5|T1G7D5_HELRO
Protein Wnt
Search

tr|T1G7D6|T1G7D6_HELRO
Uncharacterized protein
Search

0.86

Pox meso

0.70	GO:0007275	multicellular organism development
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.50	GO:0036037	CD8-positive, alpha-beta T cell activation
0.50	GO:0009653	anatomical structure morphogenesis
0.49	GO:0035710	CD4-positive, alpha-beta T cell activation
0.47	GO:0030154	cell differentiation
0.46	GO:0008283	cell proliferation

0.60	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.45	GO:0001067	regulatory region nucleic acid binding

0.61	GO:0005634	nucleus
0.34	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

tr|T1G7D7|T1G7D7_HELRO
Uncharacterized protein
Search

PAK4

0.81	p21 protein (Cdc42/Rac)-activated kinase 4 (Fragment)

0.63	GO:0006468	protein phosphorylation
0.62	GO:0016049	cell growth
0.61	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway
0.60	GO:0007613	memory
0.60	GO:0007612	learning
0.60	GO:0006915	apoptotic process
0.59	GO:0007626	locomotory behavior
0.57	GO:0007010	cytoskeleton organization
0.52	GO:0007266	Rho protein signal transduction
0.52	GO:0031098	stress-activated protein kinase signaling cascade

0.67	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0048365	Rac GTPase binding
0.49	GO:0098641	cadherin binding involved in cell-cell adhesion

0.52	GO:0005654	nucleoplasm
0.47	GO:0005913	cell-cell adherens junction
0.47	GO:0005739	mitochondrion

0.67

GO:0004674

tr|T1G7D8|T1G7D8_HELRO
POU domain protein
Search

0.61	POU domain protein (Fragment)

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.50	GO:0048513	animal organ development
0.49	GO:0007605	sensory perception of sound
0.49	GO:1902867	negative regulation of retina development in camera-type eye
0.48	GO:0007399	nervous system development
0.47	GO:0061074	regulation of neural retina development
0.47	GO:0050885	neuromuscular process controlling balance

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.46	GO:1990841	promoter-specific chromatin binding
0.45	GO:0003714	transcription corepressor activity
0.44	GO:0001012	RNA polymerase II regulatory region DNA binding
0.43	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.41	GO:0043233	organelle lumen
0.38	GO:0044446	intracellular organelle part
0.36	GO:0005737	cytoplasm

tr|T1G7D9|T1G7D9_HELRO
Uncharacterized protein
Search

tr|T1G7E0|T1G7E0_HELRO
Uncharacterized protein
Search

0.81	H/ACA ribonucleoprotein complex

0.72	GO:0001522	pseudouridine synthesis
0.67	GO:0042254	ribosome biogenesis
0.52	GO:0040031	snRNA modification
0.46	GO:0010197	polar nucleus fusion
0.45	GO:0016072	rRNA metabolic process
0.45	GO:1904874	positive regulation of telomerase RNA localization to Cajal body
0.44	GO:0007004	telomere maintenance via telomerase
0.43	GO:0034470	ncRNA processing
0.42	GO:0090501	RNA phosphodiester bond hydrolysis
0.34	GO:0006696	ergosterol biosynthetic process

0.83	GO:0030515	snoRNA binding
0.44	GO:0070034	telomerase RNA binding
0.36	GO:0000250	lanosterol synthase activity

0.56	GO:0019013	viral nucleocapsid
0.52	GO:0030529	intracellular ribonucleoprotein complex
0.50	GO:0005730	nucleolus
0.49	GO:0015030	Cajal body
0.42	GO:1902494	catalytic complex
0.34	GO:0005811	lipid droplet

0.36	EC:5.4.99.7	GO:0000250
0.36	KEGG:R03199	GO:0000250

tr|T1G7E1|T1G7E1_HELRO
Uncharacterized protein
Search

tr|T1G7E2|T1G7E2_HELRO
Uncharacterized protein
Search

0.44	T. brucei spp.-specific protein

0.30

GO:0044425

membrane part

tr|T1G7E3|T1G7E3_HELRO
Uncharacterized protein
Search

0.90	Dishevelled associated activator of morphogenesis

0.73	GO:0030036	actin cytoskeleton organization
0.41	GO:0048856	anatomical structure development
0.40	GO:2000050	regulation of non-canonical Wnt signaling pathway
0.40	GO:0048522	positive regulation of cellular process
0.39	GO:0051960	regulation of nervous system development
0.39	GO:0060284	regulation of cell development
0.39	GO:0030833	regulation of actin filament polymerization
0.39	GO:0044089	positive regulation of cellular component biogenesis
0.39	GO:0060828	regulation of canonical Wnt signaling pathway
0.38	GO:0097435	supramolecular fiber organization

0.77	GO:0017048	Rho GTPase binding
0.74	GO:0003779	actin binding
0.38	GO:0042802	identical protein binding
0.38	GO:0008017	microtubule binding

0.41	GO:0015629	actin cytoskeleton
0.40	GO:0036064	ciliary basal body
0.39	GO:0031514	motile cilium
0.38	GO:0099512	supramolecular fiber
0.37	GO:0005829	cytosol
0.35	GO:0044295	axonal growth cone
0.35	GO:0005886	plasma membrane
0.35	GO:0016528	sarcoplasm

tr|T1G7E4|T1G7E4_HELRO
Mitogen-activated protein kinase kinase kinase kinase
Search

MAP4K5

0.73	Mitogen-activated protein kinase kinase kinase kinase

0.84	GO:0000185	activation of MAPKKK activity
0.78	GO:0000165	MAPK cascade
0.45	GO:0035332	positive regulation of hippo signaling
0.45	GO:0031098	stress-activated protein kinase signaling cascade
0.45	GO:0040009	regulation of growth rate
0.44	GO:0048149	behavioral response to ethanol
0.44	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway
0.44	GO:0070328	triglyceride homeostasis
0.44	GO:0046626	regulation of insulin receptor signaling pathway
0.43	GO:0046330	positive regulation of JNK cascade

0.85	GO:0008349	MAP kinase kinase kinase kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0004697	protein kinase C activity
0.33	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity

0.45	GO:0005622	intracellular
0.37	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.85

GO:0008349

tr|T1G7E5|T1G7E5_HELRO
Uncharacterized protein
Search

tr|T1G7E6|T1G7E6_HELRO
Uncharacterized protein
Search

0.86	GO:0007084	mitotic nuclear envelope reassembly
0.85	GO:0035307	positive regulation of protein dephosphorylation
0.51	GO:0045892	negative regulation of transcription, DNA-templated
0.47	GO:0000902	cell morphogenesis
0.43	GO:0032259	methylation
0.38	GO:0042326	negative regulation of phosphorylation

0.85	GO:0051721	protein phosphatase 2A binding
0.43	GO:0008168	methyltransferase activity

0.46	GO:0043231	intracellular membrane-bounded organelle
0.45	GO:0012505	endomembrane system
0.40	GO:0044444	cytoplasmic part

0.43

GO:0008168

tr|T1G7E7|T1G7E7_HELRO
Uncharacterized protein
Search

tr|T1G7E8|T1G7E8_HELRO
Uncharacterized protein
Search

0.32

GO:0006396

RNA processing

0.59

GO:0003723

RNA binding

0.38	GO:0019013	viral nucleocapsid
0.36	GO:1990904	ribonucleoprotein complex
0.34	GO:0005730	nucleolus
0.30	GO:0031224	intrinsic component of membrane

tr|T1G7E9|T1G7E9_HELRO
Protein YIPF
Search

tr|T1G7F0|T1G7F0_HELRO
Uncharacterized protein
Search

0.45	Ribosomal RNA large subunit methyltransferase J

0.68	GO:0001510	RNA methylation
0.51	GO:0000154	rRNA modification
0.36	GO:0051301	cell division
0.36	GO:0002181	cytoplasmic translation
0.36	GO:0006400	tRNA modification
0.36	GO:0007094	mitotic spindle assembly checkpoint
0.34	GO:0006904	vesicle docking involved in exocytosis
0.33	GO:0006468	protein phosphorylation
0.32	GO:0008299	isoprenoid biosynthetic process
0.32	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

0.63	GO:0008168	methyltransferase activity
0.51	GO:0140102	catalytic activity, acting on a rRNA
0.35	GO:0140101	catalytic activity, acting on a tRNA
0.33	GO:0004672	protein kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003676	nucleic acid binding

0.41	GO:0005730	nucleolus
0.40	GO:0005737	cytoplasm
0.32	GO:0030687	preribosome, large subunit precursor
0.30	GO:0031224	intrinsic component of membrane

0.63

GO:0008168

tr|T1G7F1|T1G7F1_HELRO
Uncharacterized protein
Search

0.54

GO:0046872

metal ion binding

0.30

GO:0044425

membrane part

tr|T1G7F2|T1G7F2_HELRO
Uncharacterized protein
Search

0.62	SH2 domain-containing adapter protein F (Fragment)

0.74	GO:0009967	positive regulation of signal transduction
0.60	GO:0007165	signal transduction
0.54	GO:1900194	negative regulation of oocyte maturation
0.53	GO:0045624	positive regulation of T-helper cell differentiation
0.53	GO:0071425	hematopoietic stem cell proliferation
0.52	GO:0042100	B cell proliferation
0.50	GO:0045931	positive regulation of mitotic cell cycle
0.50	GO:0006469	negative regulation of protein kinase activity
0.50	GO:0048514	blood vessel morphogenesis
0.49	GO:0002253	activation of immune response

0.84	GO:0005070	SH3/SH2 adaptor activity
0.38	GO:0001784	phosphotyrosine residue binding
0.36	GO:0003743	translation initiation factor activity
0.35	GO:0016301	kinase activity

0.37	GO:0036464	cytoplasmic ribonucleoprotein granule
0.36	GO:0005654	nucleoplasm
0.35	GO:0005829	cytosol

tr|T1G7F3|T1G7F3_HELRO
Uncharacterized protein
Search

0.52

GO:0051179

localization

0.48	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

tr|T1G7F4|T1G7F4_HELRO
Uncharacterized protein
Search

CLUAP1

0.95	Clusterin associated protein 1

0.59

GO:0060271

cilium assembly

0.67	GO:0005654	nucleoplasm
0.62	GO:0030992	intraciliary transport particle B
0.58	GO:0005813	centrosome
0.57	GO:0005929	cilium

tr|T1G7F5|T1G7F5_HELRO
Uncharacterized protein
Search

0.79	LOW QUALITY PROTEIN: homeobox protein six1

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0048513	animal organ development
0.52	GO:0008283	cell proliferation
0.49	GO:0006915	apoptotic process
0.47	GO:0060788	ectodermal placode formation
0.46	GO:0016477	cell migration
0.45	GO:0035270	endocrine system development
0.45	GO:0009649	entrainment of circadian clock

0.64	GO:0043565	sequence-specific DNA binding
0.46	GO:0003700	DNA binding transcription factor activity
0.44	GO:0008134	transcription factor binding
0.41	GO:0001012	RNA polymerase II regulatory region DNA binding
0.40	GO:0003690	double-stranded DNA binding
0.39	GO:0032403	protein complex binding
0.36	GO:0003682	chromatin binding

0.61	GO:0005634	nucleus
0.36	GO:0005667	transcription factor complex
0.35	GO:0043233	organelle lumen
0.34	GO:0043232	intracellular non-membrane-bounded organelle
0.34	GO:0044446	intracellular organelle part
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|T1G7F6|T1G7F6_HELRO
Uncharacterized protein
Search

0.55	Gamma-secretase subunit pen-2

0.47	GO:0060465	pharynx development
0.44	GO:0007219	Notch signaling pathway
0.44	GO:0045165	cell fate commitment
0.44	GO:0007281	germ cell development
0.43	GO:0009792	embryo development ending in birth or egg hatching
0.43	GO:0048598	embryonic morphogenesis

0.30

GO:0044425

membrane part

tr|T1G7F7|T1G7F7_HELRO
Uncharacterized protein
Search

ARRB2

0.67	Beta arrestin

0.61	GO:0007165	signal transduction
0.48	GO:0043393	regulation of protein binding
0.47	GO:0002031	G-protein coupled receptor internalization
0.47	GO:0032226	positive regulation of synaptic transmission, dopaminergic
0.46	GO:0002092	positive regulation of receptor internalization
0.46	GO:0045953	negative regulation of natural killer cell mediated cytotoxicity
0.46	GO:0032691	negative regulation of interleukin-1 beta production
0.46	GO:0032695	negative regulation of interleukin-12 production
0.46	GO:2000727	positive regulation of cardiac muscle cell differentiation
0.46	GO:0034122	negative regulation of toll-like receptor signaling pathway

0.46	GO:0043422	protein kinase B binding
0.46	GO:0031701	angiotensin receptor binding
0.43	GO:0032947	protein complex scaffold activity
0.43	GO:0031625	ubiquitin protein ligase binding
0.39	GO:0031859	platelet activating factor receptor binding
0.39	GO:0031691	alpha-1A adrenergic receptor binding
0.39	GO:0031692	alpha-1B adrenergic receptor binding
0.38	GO:0031762	follicle-stimulating hormone receptor binding
0.38	GO:0031826	type 2A serotonin receptor binding
0.38	GO:0031748	D1 dopamine receptor binding

0.44	GO:0030139	endocytic vesicle
0.39	GO:0005634	nucleus
0.37	GO:0005905	clathrin-coated pit
0.37	GO:0005886	plasma membrane
0.37	GO:0030425	dendrite
0.37	GO:0044309	neuron spine
0.37	GO:0014069	postsynaptic density
0.34	GO:0043204	perikaryon
0.34	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

tr|T1G7F8|T1G7F8_HELRO
Uncharacterized protein
Search

0.10	HIV-1 Rev-binding protein (Fragment)

0.76	GO:0043547	positive regulation of GTPase activity
0.39	GO:0006468	protein phosphorylation
0.35	GO:0006529	asparagine biosynthetic process

0.76	GO:0005096	GTPase activator activity
0.52	GO:0046872	metal ion binding
0.39	GO:0004672	protein kinase activity
0.37	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0004066	asparagine synthase (glutamine-hydrolyzing) activity
0.34	GO:0019904	protein domain specific binding

0.30

GO:0016020

membrane

0.35

EC:6.3.5.4

GO:0004066

tr|T1G7F9|T1G7F9_HELRO
Uncharacterized protein
Search

0.88	T-box protein 2 (inferred by orthology to a C. elegans protein)

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.48	GO:0001708	cell fate specification
0.47	GO:0014043	negative regulation of neuron maturation
0.46	GO:0032525	somite rostral/caudal axis specification
0.45	GO:0001707	mesoderm formation
0.44	GO:0010977	negative regulation of neuron projection development
0.43	GO:0043282	pharyngeal muscle development

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.45	GO:0001102	RNA polymerase II activating transcription factor binding
0.45	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.42	GO:0001067	regulatory region nucleic acid binding
0.38	GO:0019899	enzyme binding

0.61	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm
0.34	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

tr|T1G7G0|T1G7G0_HELRO
Uncharacterized protein
Search

ATP6V0E1

0.68	V-type proton ATPase subunit

0.76	GO:0015991	ATP hydrolysis coupled proton transport
0.37	GO:0090383	phagosome acidification
0.36	GO:0033572	transferrin transport
0.36	GO:0010243	response to organonitrogen compound
0.36	GO:0060142	regulation of syncytium formation by plasma membrane fusion
0.36	GO:0010172	embryonic body morphogenesis
0.36	GO:0007035	vacuolar acidification
0.36	GO:0016241	regulation of macroautophagy
0.36	GO:1901700	response to oxygen-containing compound
0.35	GO:1901699	cellular response to nitrogen compound

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.52	GO:0036442	proton-exporting ATPase activity
0.48	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
0.33	GO:0003743	translation initiation factor activity
0.33	GO:0046983	protein dimerization activity

0.79	GO:0033179	proton-transporting V-type ATPase, V0 domain
0.36	GO:0033181	plasma membrane proton-transporting V-type ATPase complex
0.36	GO:0030670	phagocytic vesicle membrane
0.35	GO:0016324	apical plasma membrane
0.35	GO:0043296	apical junction complex
0.35	GO:0010008	endosome membrane
0.33	GO:0005576	extracellular region
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

tr|T1G7G1|T1G7G1_HELRO
Uncharacterized protein
Search

0.45	Dual specificity mitogen-activated protein kinase kinase

0.63	GO:0006468	protein phosphorylation
0.50	GO:0032147	activation of protein kinase activity
0.48	GO:0043406	positive regulation of MAP kinase activity
0.47	GO:0048082	regulation of adult chitin-containing cuticle pigmentation
0.46	GO:0051240	positive regulation of multicellular organismal process
0.46	GO:0031098	stress-activated protein kinase signaling cascade
0.46	GO:0002385	mucosal immune response
0.46	GO:0045793	positive regulation of cell size
0.45	GO:0007309	oocyte axis specification
0.45	GO:0040014	regulation of multicellular organism growth

0.64	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0004708	MAP kinase kinase activity
0.47	GO:0019901	protein kinase binding
0.35	GO:0005057	signal transducer activity, downstream of receptor
0.34	GO:0004713	protein tyrosine kinase activity

0.36	GO:0005622	intracellular
0.32	GO:0043227	membrane-bounded organelle

0.64

GO:0004674

tr|T1G7G2|T1G7G2_HELRO
Uncharacterized protein
Search

tr|T1G7G3|T1G7G3_HELRO
Uncharacterized protein
Search

0.73	Putative syntaxin-binding protein 2 (Fragment)

0.36	GO:0006904	vesicle docking involved in exocytosis
0.34	GO:0042073	intraciliary transport
0.34	GO:0045292	mRNA cis splicing, via spliceosome
0.34	GO:0007275	multicellular organism development
0.34	GO:0006106	fumarate metabolic process
0.34	GO:0060271	cilium assembly
0.34	GO:0007165	signal transduction
0.34	GO:0071773	cellular response to BMP stimulus
0.34	GO:0061615	glycolytic process through fructose-6-phosphate
0.34	GO:0060828	regulation of canonical Wnt signaling pathway

0.37	GO:0008484	sulfuric ester hydrolase activity
0.36	GO:0005509	calcium ion binding
0.34	GO:0005515	protein binding
0.34	GO:0004333	fumarate hydratase activity
0.34	GO:0003872	6-phosphofructokinase activity
0.34	GO:0004725	protein tyrosine phosphatase activity
0.34	GO:0044877	macromolecular complex binding
0.33	GO:0005261	cation channel activity
0.33	GO:0003924	GTPase activity
0.33	GO:0019001	guanyl nucleotide binding

0.34	GO:0030992	intraciliary transport particle B
0.34	GO:0072669	tRNA-splicing ligase complex
0.34	GO:0031514	motile cilium
0.34	GO:0045239	tricarboxylic acid cycle enzyme complex
0.34	GO:0005681	spliceosomal complex
0.33	GO:0005856	cytoskeleton
0.30	GO:0016020	membrane

0.37	EC:3.1.6	GO:0008484
0.34	KEGG:R01082	GO:0004333

tr|T1G7G4|T1G7G4_HELRO
Uncharacterized protein
Search

0.66	T-box transcription factor mls-1

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.44	GO:0042694	muscle cell fate specification
0.42	GO:0043282	pharyngeal muscle development
0.41	GO:0009791	post-embryonic development
0.40	GO:0042048	olfactory behavior
0.38	GO:0032880	regulation of protein localization
0.37	GO:0040011	locomotion

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.38	GO:0019899	enzyme binding
0.33	GO:0098772	molecular function regulator

0.61	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm
0.33	GO:0005667	transcription factor complex
0.33	GO:0000785	chromatin
0.30	GO:0016020	membrane

tr|T1G7G5|T1G7G5_HELRO
Uncharacterized protein
Search

0.61	GO:0007229	integrin-mediated signaling pathway
0.60	GO:0006508	proteolysis
0.41	GO:0032331	negative regulation of chondrocyte differentiation
0.40	GO:0071347	cellular response to interleukin-1
0.40	GO:1902203	negative regulation of hepatocyte growth factor receptor signaling pathway
0.40	GO:2001112	regulation of cellular response to hepatocyte growth factor stimulus
0.40	GO:0071773	cellular response to BMP stimulus
0.40	GO:0071356	cellular response to tumor necrosis factor
0.40	GO:1901509	regulation of endothelial tube morphogenesis
0.40	GO:0030167	proteoglycan catabolic process

0.69	GO:0004222	metalloendopeptidase activity
0.53	GO:0046872	metal ion binding
0.39	GO:0017124	SH3 domain binding
0.33	GO:0004867	serine-type endopeptidase inhibitor activity

0.54	GO:0005576	extracellular region
0.37	GO:0005794	Golgi apparatus
0.36	GO:0009986	cell surface
0.35	GO:0030659	cytoplasmic vesicle membrane
0.33	GO:0016323	basolateral plasma membrane
0.33	GO:0098552	side of membrane
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0004222

tr|T1G7G6|T1G7G6_HELRO
Uncharacterized protein
Search

0.95	Histone H1-gamma, late

0.78

GO:0006334

nucleosome assembly

0.54	GO:0003677	DNA binding
0.38	GO:0046982	protein heterodimerization activity

0.74	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

tr|T1G7G7|T1G7G7_HELRO
Uncharacterized protein
Search

ELP4

0.87	Elongator acetyltransferase complex subunit 4

0.77	GO:0002098	tRNA wobble uridine modification
0.50	GO:0043966	histone H3 acetylation
0.50	GO:0043967	histone H4 acetylation
0.48	GO:0006368	transcription elongation from RNA polymerase II promoter
0.45	GO:0006357	regulation of transcription by RNA polymerase II
0.41	GO:0045859	regulation of protein kinase activity
0.33	GO:0007049	cell cycle

0.50	GO:0000993	RNA polymerase II core binding
0.48	GO:0004402	histone acetyltransferase activity
0.44	GO:0008607	phosphorylase kinase regulator activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0003676	nucleic acid binding

0.82	GO:0033588	Elongator holoenzyme complex
0.50	GO:0005654	nucleoplasm
0.47	GO:0031248	protein acetyltransferase complex
0.37	GO:0005737	cytoplasm

0.48

GO:0004402

tr|T1G7G8|T1G7G8_HELRO
Uncharacterized protein
Search

0.12	Lachesin (Fragment)

0.47	GO:0006468	protein phosphorylation
0.40	GO:0035023	regulation of Rho protein signal transduction
0.38	GO:0065009	regulation of molecular function
0.37	GO:0006898	receptor-mediated endocytosis
0.35	GO:0005975	carbohydrate metabolic process

0.47	GO:0004672	protein kinase activity
0.43	GO:0032559	adenyl ribonucleotide binding
0.42	GO:0008144	drug binding
0.42	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.38	GO:0005044	scavenger receptor activity
0.36	GO:0005509	calcium ion binding

0.30

GO:0016020

membrane

tr|T1G7G9|T1G7G9_HELRO
Uncharacterized protein
Search

0.54	Serine/threonine-protein kinase N2

0.63	GO:0006468	protein phosphorylation
0.56	GO:0007165	signal transduction
0.43	GO:0018209	peptidyl-serine modification
0.40	GO:0010631	epithelial cell migration
0.38	GO:0018210	peptidyl-threonine modification
0.37	GO:2000145	regulation of cell motility
0.37	GO:0016570	histone modification
0.36	GO:0006357	regulation of transcription by RNA polymerase II
0.36	GO:0002634	regulation of germinal center formation
0.36	GO:0001783	B cell apoptotic process

0.73	GO:0017049	GTP-Rho binding
0.70	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0050681	androgen receptor binding
0.39	GO:0035173	histone kinase activity
0.38	GO:0005080	protein kinase C binding
0.38	GO:0048365	Rac GTPase binding
0.38	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity

0.38	GO:0097610	cell surface furrow
0.38	GO:0030496	midbody
0.38	GO:0032155	cell division site part
0.37	GO:0005768	endosome
0.35	GO:0005634	nucleus
0.33	GO:0043234	protein complex
0.32	GO:0030027	lamellipodium
0.32	GO:0030054	cell junction
0.31	GO:0005856	cytoskeleton
0.30	GO:0016020	membrane

0.70

GO:0004674

tr|T1G7H0|T1G7H0_HELRO
Uncharacterized protein
Search

AHSA1

0.93	Activator of 90 kDa heat shock protein ATPase

0.81	GO:0032781	positive regulation of ATPase activity
0.61	GO:0006950	response to stress
0.37	GO:0048702	embryonic neurocranium morphogenesis
0.35	GO:0006471	protein ADP-ribosylation
0.33	GO:0006457	protein folding

0.82	GO:0001671	ATPase activator activity
0.77	GO:0051087	chaperone binding
0.49	GO:0045296	cadherin binding
0.35	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.33	GO:0008270	zinc ion binding
0.32	GO:0003677	DNA binding
0.32	GO:0051287	NAD binding

0.44	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.35	GO:0005783	endoplasmic reticulum
0.32	GO:0005634	nucleus

0.35

GO:0003950

tr|T1G7H1|T1G7H1_HELRO
Uncharacterized protein
Search

APT

0.48	Adenine phosphoribosyltransferase

0.79	GO:0006168	adenine salvage
0.73	GO:0044209	AMP salvage
0.73	GO:0006166	purine ribonucleoside salvage
0.34	GO:0007625	grooming behavior

0.80	GO:0003999	adenine phosphoribosyltransferase activity
0.35	GO:0002055	adenine binding
0.34	GO:0016208	AMP binding
0.32	GO:0016787	hydrolase activity

0.49	GO:0005737	cytoplasm
0.33	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

0.80

EC:2.4.2.7

GO:0003999

tr|T1G7H2|T1G7H2_HELRO
Uncharacterized protein
Search

TFG

0.92	Trk-fused gene (Fragment)

0.85	GO:0048208	COPII vesicle coating
0.37	GO:1902533	positive regulation of intracellular signal transduction
0.37	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling
0.35	GO:0007165	signal transduction
0.34	GO:0043405	regulation of MAP kinase activity
0.34	GO:0032147	activation of protein kinase activity
0.34	GO:0071902	positive regulation of protein serine/threonine kinase activity
0.34	GO:0048666	neuron development
0.34	GO:0018108	peptidyl-tyrosine phosphorylation

0.74	GO:0042802	identical protein binding
0.36	GO:0004871	signal transducer activity
0.34	GO:0099600	transmembrane receptor activity
0.34	GO:0004713	protein tyrosine kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.74	GO:0000139	Golgi membrane
0.53	GO:0070971	endoplasmic reticulum exit site
0.37	GO:0070062	extracellular exosome
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0004713

tr|T1G7H3|T1G7H3_HELRO
Uncharacterized protein
Search

SLC13A5

0.82	Sodium-dependent citrate transporter

0.73	GO:0006814	sodium ion transport
0.55	GO:0055085	transmembrane transport
0.49	GO:0015744	succinate transport
0.49	GO:0015746	citrate transport
0.36	GO:0008272	sulfate transport
0.34	GO:0070778	L-aspartate transport
0.33	GO:0006357	regulation of transcription by RNA polymerase II
0.32	GO:0006520	cellular amino acid metabolic process

0.56	GO:0005215	transporter activity
0.34	GO:0001104	RNA polymerase II transcription cofactor activity
0.33	GO:0030170	pyridoxal phosphate binding

0.41	GO:0005887	integral component of plasma membrane
0.34	GO:0016323	basolateral plasma membrane
0.33	GO:0070062	extracellular exosome
0.33	GO:0016592	mediator complex

tr|T1G7H4|T1G7H4_HELRO
Uncharacterized protein
Search

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.44	GO:0048731	system development
0.42	GO:0007605	sensory perception of sound
0.42	GO:0007626	locomotory behavior
0.40	GO:0048468	cell development
0.40	GO:0120036	plasma membrane bounded cell projection organization
0.39	GO:0007267	cell-cell signaling
0.38	GO:0072137	condensed mesenchymal cell proliferation
0.36	GO:0060471	cortical granule exocytosis
0.35	GO:0007010	cytoskeleton organization

0.70	GO:0005509	calcium ion binding
0.33	GO:0050839	cell adhesion molecule binding
0.33	GO:0032403	protein complex binding
0.33	GO:0004930	G-protein coupled receptor activity

0.56	GO:0005886	plasma membrane
0.43	GO:0098858	actin-based cell projection
0.42	GO:0032421	stereocilium bundle
0.41	GO:0043005	neuron projection
0.36	GO:0044422	organelle part
0.36	GO:0030054	cell junction
0.35	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0045177	apical part of cell
0.34	GO:0030027	lamellipodium
0.34	GO:0031254	cell trailing edge

tr|T1G7H5|T1G7H5_HELRO
Uncharacterized protein
Search

0.37	Calcium binding protein 39

0.77	GO:0001700	embryonic development via the syncytial blastoderm
0.49	GO:0060583	regulation of actin cortical patch localization
0.48	GO:0071574	protein localization to medial cortex
0.47	GO:2000099	regulation of establishment or maintenance of bipolar cell polarity
0.47	GO:2000769	regulation of establishment or maintenance of cell polarity regulating cell shape
0.43	GO:0006357	regulation of transcription by RNA polymerase II
0.40	GO:0006468	protein phosphorylation

0.46	GO:0001104	RNA polymerase II transcription cofactor activity
0.40	GO:0004672	protein kinase activity

0.59	GO:0005634	nucleus
0.49	GO:0071958	new mitotic spindle pole body
0.48	GO:0035839	non-growing cell tip
0.47	GO:0005737	cytoplasm
0.43	GO:0032153	cell division site
0.42	GO:0031974	membrane-enclosed lumen
0.40	GO:0043234	protein complex
0.30	GO:0016020	membrane

tr|T1G7H6|T1G7H6_HELRO
Uncharacterized protein
Search

0.50	casein kinase I

0.63	GO:0006468	protein phosphorylation
0.49	GO:0016318	ommatidial rotation
0.49	GO:2001135	regulation of endocytic recycling
0.48	GO:0008355	olfactory learning
0.48	GO:0007291	sperm individualization
0.48	GO:0008347	glial cell migration
0.47	GO:0051126	negative regulation of actin nucleation
0.47	GO:0090175	regulation of establishment of planar polarity
0.43	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.43	GO:0009612	response to mechanical stimulus

0.69	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0005198	structural molecule activity

0.49	GO:0070864	sperm individualization complex
0.41	GO:0005634	nucleus
0.38	GO:0005886	plasma membrane
0.35	GO:0005829	cytosol
0.35	GO:0005818	aster
0.34	GO:0005938	cell cortex
0.34	GO:0005923	bicellular tight junction
0.30	GO:0016021	integral component of membrane

0.69

GO:0004674

tr|T1G7H7|T1G7H7_HELRO
Uncharacterized protein
Search

tr|T1G7H8|T1G7H8_HELRO
Uncharacterized protein
Search

0.30	45 kDa calcium-binding protein

0.70

GO:0005509

calcium ion binding

tr|T1G7H9|T1G7H9_HELRO
Uncharacterized protein
Search

0.54	Centromeric protein A

0.40	GO:0061641	CENP-A containing chromatin organization
0.36	GO:0006334	nucleosome assembly
0.35	GO:0051382	kinetochore assembly
0.35	GO:0000070	mitotic sister chromatid segregation
0.33	GO:0008033	tRNA processing
0.32	GO:0032259	methylation

0.74	GO:0046982	protein heterodimerization activity
0.55	GO:0003677	DNA binding
0.37	GO:0031491	nucleosome binding
0.32	GO:0008168	methyltransferase activity

0.75	GO:0000786	nucleosome
0.60	GO:0005634	nucleus
0.40	GO:0061638	CENP-A containing chromatin
0.38	GO:0000779	condensed chromosome, centromeric region
0.36	GO:0031974	membrane-enclosed lumen
0.34	GO:0000776	kinetochore

0.32

GO:0008168

tr|T1G7I0|T1G7I0_HELRO
Uncharacterized protein
Search

0.53

Tenascin

0.68	GO:0007596	blood coagulation
0.61	GO:0001775	cell activation
0.60	GO:0051258	protein polymerization
0.49	GO:0007165	signal transduction
0.41	GO:0050790	regulation of catalytic activity
0.40	GO:0042176	regulation of protein catabolic process
0.38	GO:0001525	angiogenesis
0.38	GO:0043066	negative regulation of apoptotic process
0.37	GO:0006508	proteolysis
0.35	GO:0055085	transmembrane transport

0.61	GO:0030674	protein binding, bridging
0.57	GO:0005102	receptor binding
0.45	GO:0005509	calcium ion binding
0.41	GO:0030234	enzyme regulator activity
0.39	GO:0004222	metalloendopeptidase activity
0.38	GO:0008270	zinc ion binding

0.66	GO:0005577	fibrinogen complex
0.42	GO:1905369	endopeptidase complex
0.34	GO:0044424	intracellular part
0.30	GO:0016020	membrane

0.39

GO:0004222

tr|T1G7I1|T1G7I1_HELRO
Uncharacterized protein
Search

0.40	SECIS-binding protein 2

tr|T1G7I2|T1G7I2_HELRO
Uncharacterized protein
Search

0.92	Winged helix protein CWH-4 (Fragment)

0.57	GO:0006355	regulation of transcription, DNA-templated
0.49	GO:0009653	anatomical structure morphogenesis
0.48	GO:0030154	cell differentiation
0.44	GO:0009888	tissue development
0.44	GO:0009792	embryo development ending in birth or egg hatching
0.43	GO:0003002	regionalization
0.43	GO:0000578	embryonic axis specification
0.42	GO:0006351	transcription, DNA-templated
0.41	GO:0048731	system development
0.41	GO:1902747	negative regulation of lens fiber cell differentiation

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.40	GO:0001012	RNA polymerase II regulatory region DNA binding
0.39	GO:0001106	RNA polymerase II transcription corepressor activity
0.39	GO:0003690	double-stranded DNA binding
0.37	GO:0008301	DNA binding, bending
0.34	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.37	GO:0005667	transcription factor complex
0.33	GO:0000785	chromatin
0.33	GO:0070013	intracellular organelle lumen

tr|T1G7I3|T1G7I3_HELRO
Uncharacterized protein
Search

CASD1

0.62	N-acetylneuraminate 9-O-acetyltransferase

0.42	GO:0005975	carbohydrate metabolic process
0.34	GO:0006493	protein O-linked glycosylation
0.34	GO:0097502	mannosylation

0.56	GO:0047186	N-acetylneuraminate 7-O(or 9-O)-acetyltransferase activity
0.36	GO:0005201	extracellular matrix structural constituent
0.34	GO:0000030	mannosyltransferase activity
0.33	GO:0005515	protein binding

0.51	GO:0030173	integral component of Golgi membrane
0.36	GO:0005581	collagen trimer
0.33	GO:0005739	mitochondrion

0.56

EC:2.3.1.45

GO:0047186

tr|T1G7I4|T1G7I4_HELRO
Uncharacterized protein
Search

0.85	sn 12 diacylglycerol ethanolamine and cholinephosphotransferase

0.67	GO:0008654	phospholipid biosynthetic process
0.37	GO:0046470	phosphatidylcholine metabolic process
0.37	GO:0045017	glycerolipid biosynthetic process
0.35	GO:0046469	platelet activating factor metabolic process
0.35	GO:0006885	regulation of pH
0.35	GO:0035725	sodium ion transmembrane transport
0.35	GO:0006658	phosphatidylserine metabolic process
0.34	GO:1901566	organonitrogen compound biosynthetic process
0.33	GO:1902600	hydrogen ion transmembrane transport
0.33	GO:0007186	G-protein coupled receptor signaling pathway

0.70	GO:0016780	phosphotransferase activity, for other substituted phosphate groups
0.35	GO:0015385	sodium:proton antiporter activity
0.33	GO:0046872	metal ion binding
0.33	GO:0004930	G-protein coupled receptor activity

0.35	GO:0000139	Golgi membrane
0.30	GO:0016021	integral component of membrane

0.70

EC:2.7.8

GO:0016780

tr|T1G7I5|T1G7I5_HELRO
Uncharacterized protein
Search

PFDN6

0.90	Prefoldin subunit 6

0.69	GO:0006457	protein folding
0.58	GO:0051131	chaperone-mediated protein complex assembly
0.34	GO:0006898	receptor-mediated endocytosis
0.33	GO:0006629	lipid metabolic process
0.32	GO:0055114	oxidation-reduction process

0.71	GO:0051082	unfolded protein binding
0.55	GO:0051087	chaperone binding
0.35	GO:0005044	scavenger receptor activity
0.34	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors

0.80	GO:0016272	prefoldin complex
0.37	GO:0005737	cytoplasm
0.34	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:1.3

GO:0016627

tr|T1G7I6|T1G7I6_HELRO
Uncharacterized protein
Search

TIMELESS

0.64	Timeless circadian clock

0.86	GO:1904976	cellular response to bleomycin
0.85	GO:0072719	cellular response to cisplatin
0.85	GO:0072711	cellular response to hydroxyurea
0.84	GO:2000781	positive regulation of double-strand break repair
0.80	GO:0042752	regulation of circadian rhythm
0.79	GO:0048754	branching morphogenesis of an epithelial tube
0.79	GO:0030324	lung development
0.77	GO:0007623	circadian rhythm
0.77	GO:0044770	cell cycle phase transition
0.74	GO:0000122	negative regulation of transcription by RNA polymerase II

0.71	GO:0042803	protein homodimerization activity
0.70	GO:0046982	protein heterodimerization activity

0.71	GO:0000790	nuclear chromatin
0.37	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

tr|T1G7I7|T1G7I7_HELRO
Uncharacterized protein
Search

A1CF

0.52	APOBEC1 complementation factor

0.73	GO:0016556	mRNA modification
0.55	GO:0010609	mRNA localization resulting in posttranscriptional regulation of gene expression
0.53	GO:0016554	cytidine to uridine editing
0.50	GO:0007566	embryo implantation
0.38	GO:0050821	protein stabilization
0.36	GO:0006397	mRNA processing

0.73	GO:0003727	single-stranded RNA binding
0.37	GO:0003725	double-stranded RNA binding
0.35	GO:0005515	protein binding
0.34	GO:0003729	mRNA binding

0.83	GO:0030895	apolipoprotein B mRNA editing enzyme complex
0.47	GO:0005654	nucleoplasm
0.38	GO:0005737	cytoplasm
0.36	GO:0012505	endomembrane system
0.35	GO:0045293	mRNA editing complex
0.34	GO:0005720	nuclear heterochromatin
0.30	GO:0031224	intrinsic component of membrane

tr|T1G7I8|T1G7I8_HELRO
Uncharacterized protein
Search

0.53	HIRA interacting protein 5

0.74	GO:0016226	iron-sulfur cluster assembly
0.33	GO:0006470	protein dephosphorylation
0.33	GO:0032259	methylation
0.32	GO:1901137	carbohydrate derivative biosynthetic process

0.64	GO:0051536	iron-sulfur cluster binding
0.63	GO:0005506	iron ion binding
0.33	GO:0004360	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
0.33	GO:0005515	protein binding
0.33	GO:0004721	phosphoprotein phosphatase activity
0.33	GO:0008168	methyltransferase activity
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0003676	nucleic acid binding

0.41	GO:0005654	nucleoplasm
0.41	GO:0005829	cytosol
0.41	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.33	EC:2.6.1.16	GO:0004360
0.33	KEGG:R00768	GO:0004360

tr|T1G7I9|T1G7I9_HELRO
Uncharacterized protein
Search

ADIPOR2

0.83	Adiponectin receptor

0.58	GO:0033211	adiponectin-activated signaling pathway
0.54	GO:0061042	vascular wound healing
0.52	GO:0042593	glucose homeostasis
0.42	GO:0036099	female germ-line stem cell population maintenance
0.42	GO:0051050	positive regulation of transport
0.42	GO:0070328	triglyceride homeostasis
0.41	GO:0050796	regulation of insulin secretion
0.40	GO:1904951	positive regulation of establishment of protein localization
0.39	GO:0023056	positive regulation of signaling
0.39	GO:0010647	positive regulation of cell communication

0.56	GO:0097003	adipokinetic hormone receptor activity
0.56	GO:0055100	adiponectin binding
0.47	GO:0046982	protein heterodimerization activity
0.47	GO:0042802	identical protein binding
0.33	GO:0046872	metal ion binding

0.45	GO:0031226	intrinsic component of plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1G7J0|T1G7J0_HELRO
Ferritin
Search

0.54

Ferritin

0.76	GO:0006879	cellular iron ion homeostasis
0.75	GO:0006826	iron ion transport
0.50	GO:0055114	oxidation-reduction process
0.43	GO:0051238	sequestering of metal ion
0.41	GO:0051651	maintenance of location in cell
0.34	GO:0008285	negative regulation of cell proliferation
0.33	GO:0006955	immune response

0.76	GO:0004322	ferroxidase activity
0.75	GO:0008199	ferric iron binding
0.36	GO:0042802	identical protein binding

0.35	GO:0005737	cytoplasm
0.34	GO:0008043	intracellular ferritin complex
0.32	GO:0043227	membrane-bounded organelle
0.32	GO:0043229	intracellular organelle

0.76

EC:1.16.3.1

GO:0004322

tr|T1G7J1|T1G7J1_HELRO
Uncharacterized protein
Search

0.36	Serine/threonine-protein kinase Doa

0.63	GO:0006468	protein phosphorylation
0.48	GO:0006486	protein glycosylation
0.36	GO:0010212	response to ionizing radiation
0.36	GO:0043484	regulation of RNA splicing
0.34	GO:0032526	response to retinoic acid
0.34	GO:0045721	negative regulation of gluconeogenesis
0.34	GO:0018212	peptidyl-tyrosine modification

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0016757	transferase activity, transferring glycosyl groups
0.35	GO:0042802	identical protein binding

0.35	GO:0016604	nuclear body
0.30	GO:0031224	intrinsic component of membrane

0.44

GO:0016757

tr|T1G7J2|T1G7J2_HELRO
Uncharacterized protein
Search

0.76	Chaperone for wingless signaling and trafficking of LDL receptor

0.69	GO:0006457	protein folding
0.42	GO:0006888	ER to Golgi vesicle-mediated transport
0.41	GO:0006612	protein targeting to membrane
0.39	GO:1904395	positive regulation of skeletal muscle acetylcholine-gated channel clustering
0.38	GO:0034394	protein localization to cell surface
0.37	GO:0016925	protein sumoylation
0.37	GO:0006909	phagocytosis

0.42	GO:0042802	identical protein binding
0.38	GO:0050750	low-density lipoprotein particle receptor binding
0.38	GO:0019789	SUMO transferase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.43	GO:0005788	endoplasmic reticulum lumen
0.43	GO:0045177	apical part of cell
0.34	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1G7J3|T1G7J3_HELRO
Receptor protein serine/threonine kinase
Search

0.42	Receptor protein serine/threonine kinase

0.79	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
0.66	GO:0023014	signal transduction by protein phosphorylation
0.53	GO:0071560	cellular response to transforming growth factor beta stimulus
0.34	GO:0006914	autophagy
0.33	GO:0006166	purine ribonucleoside salvage
0.33	GO:0006167	AMP biosynthetic process

0.79	GO:0004702	signal transducer, downstream of receptor, with serine/threonine kinase activity
0.72	GO:0004675	transmembrane receptor protein serine/threonine kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0046872	metal ion binding
0.34	GO:0004001	adenosine kinase activity
0.33	GO:0008080	N-acetyltransferase activity
0.33	GO:0001871	pattern binding
0.32	GO:0003723	RNA binding

0.52	GO:0043235	receptor complex
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.79

GO:0004702

tr|T1G7J4|T1G7J4_HELRO
Uncharacterized protein
Search

EIF4G2

0.83	Eukaryotic translation initiation factor 4 gamma

0.64	GO:0006413	translational initiation
0.42	GO:0030307	positive regulation of cell growth
0.41	GO:0006446	regulation of translational initiation
0.41	GO:0007498	mesoderm development
0.40	GO:0060999	positive regulation of dendritic spine development
0.39	GO:0050772	positive regulation of axonogenesis
0.39	GO:0030516	regulation of axon extension
0.39	GO:0048639	positive regulation of developmental growth
0.38	GO:0007507	heart development
0.38	GO:0045727	positive regulation of translation

0.64	GO:0003743	translation initiation factor activity
0.39	GO:0045296	cadherin binding

0.47	GO:0005829	cytosol
0.44	GO:0016281	eukaryotic translation initiation factor 4F complex
0.39	GO:0005913	cell-cell adherens junction
0.38	GO:0030424	axon
0.30	GO:0016020	membrane

tr|T1G7J5|T1G7J5_HELRO
Uncharacterized protein
Search

0.39	Zinc finger protein (Fragment)

0.47	GO:1903506	regulation of nucleic acid-templated transcription
0.47	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.47	GO:0010468	regulation of gene expression
0.37	GO:0071294	cellular response to zinc ion
0.37	GO:0006351	transcription, DNA-templated
0.35	GO:1902679	negative regulation of RNA biosynthetic process
0.35	GO:0044791	positive regulation by host of viral release from host cell
0.34	GO:0042254	ribosome biogenesis
0.33	GO:0007275	multicellular organism development

0.48	GO:0003676	nucleic acid binding
0.45	GO:0046872	metal ion binding
0.38	GO:0003700	DNA binding transcription factor activity
0.34	GO:0005515	protein binding

0.40	GO:0005622	intracellular
0.38	GO:0043227	membrane-bounded organelle

tr|T1G7J6|T1G7J6_HELRO
Uncharacterized protein
Search

MGAT2

0.83	Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

0.73	GO:0009312	oligosaccharide biosynthetic process
0.38	GO:0006487	protein N-linked glycosylation
0.33	GO:0006364	rRNA processing

0.86	GO:0008455	alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity
0.34	GO:0042302	structural constituent of cuticle

0.80	GO:0005795	Golgi stack
0.34	GO:0032040	small-subunit processome
0.34	GO:0005581	collagen trimer
0.30	GO:0031224	intrinsic component of membrane

0.86

EC:2.4.1.143

GO:0008455

tr|T1G7J7|T1G7J7_HELRO
Uncharacterized protein
Search

USP14

0.51	Ubiquitin carboxyl-terminal hydrolase

0.76	GO:0016579	protein deubiquitination
0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.44	GO:1903070	negative regulation of ER-associated ubiquitin-dependent protein catabolic process
0.42	GO:0050920	regulation of chemotaxis
0.41	GO:0007268	chemical synaptic transmission
0.40	GO:0010951	negative regulation of endopeptidase activity
0.40	GO:0016567	protein ubiquitination
0.34	GO:0008063	Toll signaling pathway
0.34	GO:0007623	circadian rhythm
0.33	GO:0043087	regulation of GTPase activity

0.77	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.42	GO:0070628	proteasome binding
0.40	GO:0004866	endopeptidase inhibitor activity
0.33	GO:0016740	transferase activity

0.40	GO:0009986	cell surface
0.40	GO:0045202	synapse
0.40	GO:0031410	cytoplasmic vesicle
0.39	GO:0005829	cytosol
0.38	GO:0005634	nucleus
0.34	GO:0070062	extracellular exosome
0.33	GO:0043233	organelle lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.77

GO:0036459

tr|T1G7J8|T1G7J8_HELRO
Uncharacterized protein
Search

SIM1

0.80	Single-minded family bHLH transcription factor 1

0.56	GO:0006351	transcription, DNA-templated
0.55	GO:2001141	regulation of RNA biosynthetic process
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.51	GO:0035295	tube development
0.50	GO:0009880	embryonic pattern specification
0.49	GO:0048731	system development
0.45	GO:0051253	negative regulation of RNA metabolic process
0.45	GO:0010558	negative regulation of macromolecule biosynthetic process
0.45	GO:0031327	negative regulation of cellular biosynthetic process

0.68	GO:0046983	protein dimerization activity
0.56	GO:0003700	DNA binding transcription factor activity
0.52	GO:0003677	DNA binding

0.59	GO:0005634	nucleus
0.47	GO:0005667	transcription factor complex
0.43	GO:0031974	membrane-enclosed lumen
0.40	GO:0044446	intracellular organelle part
0.37	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1G7J9|T1G7J9_HELRO
Uncharacterized protein
Search

0.83	Cyclin dependent kinase 16

0.63	GO:0006468	protein phosphorylation
0.48	GO:0030252	growth hormone secretion
0.46	GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus
0.45	GO:0031175	neuron projection development
0.45	GO:0006887	exocytosis
0.44	GO:0007283	spermatogenesis
0.37	GO:0051726	regulation of cell cycle
0.35	GO:0051301	cell division
0.34	GO:0006368	transcription elongation from RNA polymerase II promoter
0.33	GO:0045944	positive regulation of transcription by RNA polymerase II

0.66	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0097472	cyclin-dependent protein kinase activity
0.35	GO:0005515	protein binding
0.34	GO:0044212	transcription regulatory region DNA binding

0.46	GO:0008021	synaptic vesicle
0.44	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.42	GO:0015630	microtubule cytoskeleton
0.41	GO:0005829	cytosol
0.40	GO:0005634	nucleus
0.34	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.34	GO:0043005	neuron projection
0.34	GO:0030054	cell junction
0.33	GO:0005694	chromosome
0.33	GO:0031974	membrane-enclosed lumen

0.66

GO:0004674

tr|T1G7K0|T1G7K0_HELRO
Synaptotagmin 7c
Search

0.73	Synaptotagmin VIIb

0.72	GO:0006887	exocytosis
0.56	GO:0099643	signal release from synapse
0.56	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.53	GO:0006836	neurotransmitter transport
0.51	GO:0001505	regulation of neurotransmitter levels
0.50	GO:0051649	establishment of localization in cell
0.44	GO:0017158	regulation of calcium ion-dependent exocytosis
0.43	GO:0097479	synaptic vesicle localization
0.43	GO:0099003	vesicle-mediated transport in synapse
0.42	GO:0006906	vesicle fusion

0.80	GO:0005544	calcium-dependent phospholipid binding
0.42	GO:0000149	SNARE binding
0.41	GO:0030276	clathrin binding
0.39	GO:0005509	calcium ion binding
0.35	GO:0001786	phosphatidylserine binding
0.35	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.34	GO:0005516	calmodulin binding

0.55	GO:0098793	presynapse
0.54	GO:0070382	exocytic vesicle
0.46	GO:0016528	sarcoplasm
0.44	GO:0005764	lysosome
0.36	GO:0005886	plasma membrane
0.35	GO:0032009	early phagosome
0.35	GO:0030658	transport vesicle membrane
0.35	GO:0044306	neuron projection terminus
0.34	GO:0043025	neuronal cell body
0.34	GO:0030425	dendrite

tr|T1G7K1|T1G7K1_HELRO
Uncharacterized protein
Search

tr|T1G7K2|T1G7K2_HELRO
Uncharacterized protein
Search

tr|T1G7K3|T1G7K3_HELRO
Uncharacterized protein
Search

0.57	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0035295	tube development
0.51	GO:0048731	system development
0.47	GO:0009880	embryonic pattern specification
0.46	GO:0060429	epithelium development
0.43	GO:0051253	negative regulation of RNA metabolic process
0.43	GO:0010558	negative regulation of macromolecule biosynthetic process

0.64	GO:0046983	protein dimerization activity
0.60	GO:0003700	DNA binding transcription factor activity
0.54	GO:0003677	DNA binding
0.38	GO:0001067	regulatory region nucleic acid binding

0.61	GO:0005634	nucleus
0.50	GO:0005667	transcription factor complex
0.42	GO:0031974	membrane-enclosed lumen
0.39	GO:0044446	intracellular organelle part
0.38	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1G7K4|T1G7K4_HELRO
Uncharacterized protein
Search

0.55	GO:0055085	transmembrane transport
0.44	GO:0043252	sodium-independent organic anion transport
0.43	GO:0015747	urate transport
0.41	GO:0015879	carnitine transport
0.40	GO:0009437	carnitine metabolic process
0.39	GO:0015698	inorganic anion transport
0.39	GO:0072337	modified amino acid transport
0.37	GO:0008643	carbohydrate transport

0.55

GO:0022857

transmembrane transporter activity

0.42

GO:0005887

integral component of plasma membrane

tr|T1G7K5|T1G7K5_HELRO
Uncharacterized protein
Search

ATP6V0E1

0.60	V-type proton ATPase subunit e

0.76	GO:0015991	ATP hydrolysis coupled proton transport
0.40	GO:0060142	regulation of syncytium formation by plasma membrane fusion
0.40	GO:0010172	embryonic body morphogenesis
0.39	GO:0009792	embryo development ending in birth or egg hatching
0.37	GO:0006433	prolyl-tRNA aminoacylation
0.35	GO:0010243	response to organonitrogen compound
0.35	GO:0090383	phagosome acidification
0.35	GO:1901700	response to oxygen-containing compound
0.35	GO:0033572	transferrin transport
0.35	GO:0007035	vacuolar acidification

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.51	GO:0036442	proton-exporting ATPase activity
0.47	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
0.37	GO:0004827	proline-tRNA ligase activity
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0008144	drug binding
0.33	GO:0003743	translation initiation factor activity
0.33	GO:0003924	GTPase activity

0.79	GO:0033179	proton-transporting V-type ATPase, V0 domain
0.40	GO:0033181	plasma membrane proton-transporting V-type ATPase complex
0.39	GO:0016324	apical plasma membrane
0.39	GO:0043296	apical junction complex
0.35	GO:0030670	phagocytic vesicle membrane
0.34	GO:0010008	endosome membrane
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.37

EC:6.1.1.15

GO:0004827

tr|T1G7K6|T1G7K6_HELRO
Uncharacterized protein
Search

0.61	Proto-oncogene vav

0.74	GO:0007264	small GTPase mediated signal transduction
0.73	GO:0035023	regulation of Rho protein signal transduction
0.62	GO:0065009	regulation of molecular function
0.60	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity
0.59	GO:0030593	neutrophil chemotaxis
0.58	GO:0008361	regulation of cell size
0.58	GO:0030217	T cell differentiation
0.57	GO:0006909	phagocytosis
0.55	GO:0007229	integrin-mediated signaling pathway
0.54	GO:0045785	positive regulation of cell adhesion

0.73	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.60	GO:0001784	phosphotyrosine residue binding
0.59	GO:0048365	Rac GTPase binding
0.50	GO:0046872	metal ion binding
0.38	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.37	GO:0030674	protein binding, bridging
0.34	GO:0003700	DNA binding transcription factor activity

0.54	GO:0005911	cell-cell junction
0.45	GO:0005622	intracellular
0.38	GO:1990429	peroxisomal importomer complex
0.36	GO:0043227	membrane-bounded organelle
0.36	GO:0098805	whole membrane
0.34	GO:0044422	organelle part
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.38	EC:2.7.1.153	GO:0046934
0.38	KEGG:R04545	GO:0046934

tr|T1G7K7|T1G7K7_HELRO
Uncharacterized protein
Search

0.10	Putative stoned b synaptic vesicle bioproteinsis protein (Fragment)

0.71	GO:0006897	endocytosis
0.70	GO:0036465	synaptic vesicle recycling
0.64	GO:0030100	regulation of endocytosis
0.49	GO:0046907	intracellular transport
0.47	GO:0015031	protein transport
0.46	GO:0034613	cellular protein localization
0.46	GO:1903421	regulation of synaptic vesicle recycling
0.44	GO:0097480	establishment of synaptic vesicle localization
0.44	GO:0099003	vesicle-mediated transport in synapse
0.43	GO:0007268	chemical synaptic transmission

0.45

GO:0097110

scaffold protein binding

0.64	GO:0098793	presynapse
0.51	GO:0030131	clathrin adaptor complex
0.44	GO:0099738	cell cortex region
0.44	GO:0070382	exocytic vesicle
0.44	GO:0030139	endocytic vesicle
0.43	GO:0030863	cortical cytoskeleton
0.34	GO:0030054	cell junction
0.30	GO:0016021	integral component of membrane

tr|T1G7K8|T1G7K8_HELRO
Uncharacterized protein
Search

0.34	Guanylate cyclase

0.79	GO:0006182	cGMP biosynthetic process
0.63	GO:0035556	intracellular signal transduction
0.61	GO:0006468	protein phosphorylation
0.45	GO:0050908	detection of light stimulus involved in visual perception
0.37	GO:0003031	detection of carbon dioxide
0.36	GO:0018212	peptidyl-tyrosine modification
0.36	GO:1904457	positive regulation of neuronal action potential
0.36	GO:0071468	cellular response to acidic pH
0.36	GO:0045921	positive regulation of exocytosis
0.35	GO:0050907	detection of chemical stimulus involved in sensory perception

0.79	GO:0004383	guanylate cyclase activity
0.61	GO:0004672	protein kinase activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0004016	adenylate cyclase activity
0.38	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.35	GO:0032550	purine ribonucleoside binding
0.35	GO:0019001	guanyl nucleotide binding
0.35	GO:0004872	receptor activity

0.47	GO:0008074	guanylate cyclase complex, soluble
0.38	GO:0005886	plasma membrane
0.36	GO:0097730	non-motile cilium
0.36	GO:0097458	neuron part
0.35	GO:0044297	cell body
0.34	GO:0005640	nuclear outer membrane
0.34	GO:0044441	ciliary part
0.33	GO:0005874	microtubule
0.30	GO:0016021	integral component of membrane

0.79

GO:0004383

tr|T1G7K9|T1G7K9_HELRO
Sepiapterin reductase
Search

SPR

0.73	Sepiapterin reductase

0.80	GO:0046146	tetrahydrobiopterin metabolic process
0.80	GO:0034312	diol biosynthetic process
0.72	GO:0042559	pteridine-containing compound biosynthetic process
0.64	GO:0009108	coenzyme biosynthetic process
0.57	GO:0006809	nitric oxide biosynthetic process
0.52	GO:0055114	oxidation-reduction process
0.42	GO:0019889	pteridine metabolic process
0.42	GO:0050882	voluntary musculoskeletal movement
0.41	GO:0042415	norepinephrine metabolic process
0.41	GO:0042428	serotonin metabolic process

0.86	GO:0004757	sepiapterin reductase activity
0.39	GO:0102306	benzil reductase [(S)-benzoin-forming] activity
0.38	GO:0042803	protein homodimerization activity
0.33	GO:0022857	transmembrane transporter activity

0.49	GO:0005654	nucleoplasm
0.48	GO:0005829	cytosol
0.37	GO:0070062	extracellular exosome
0.36	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.86

EC:1.1.1.153

GO:0004757

tr|T1G7L0|T1G7L0_HELRO
Uncharacterized protein
Search

WDR83

0.69	Mitogen-activated protein kinase organizer 1

0.68	GO:0000398	mRNA splicing, via spliceosome
0.46	GO:0016310	phosphorylation
0.37	GO:0006464	cellular protein modification process
0.37	GO:0016569	covalent chromatin modification
0.35	GO:0035556	intracellular signal transduction

0.47	GO:0016301	kinase activity
0.37	GO:0004402	histone acetyltransferase activity
0.35	GO:0005515	protein binding
0.34	GO:0043531	ADP binding
0.34	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.34	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0005524	ATP binding

0.74	GO:0071013	catalytic step 2 spliceosome
0.46	GO:0005737	cytoplasm
0.37	GO:0097708	intracellular vesicle
0.37	GO:0098805	whole membrane
0.36	GO:0098588	bounding membrane of organelle
0.36	GO:0012505	endomembrane system

0.37

GO:0004402

tr|T1G7L1|T1G7L1_HELRO
Uncharacterized protein
Search

0.71	Discs, large homolog 3 (Drosophila) (Fragment)

0.85	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity
0.85	GO:0001736	establishment of planar polarity
0.83	GO:0097120	receptor localization to synapse
0.82	GO:0010923	negative regulation of phosphatase activity
0.81	GO:0043113	receptor clustering
0.81	GO:0061098	positive regulation of protein tyrosine kinase activity
0.74	GO:0046710	GDP metabolic process
0.73	GO:0007268	chemical synaptic transmission
0.71	GO:0046037	GMP metabolic process
0.70	GO:0007399	nervous system development

0.84	GO:0035255	ionotropic glutamate receptor binding
0.83	GO:0019902	phosphatase binding
0.80	GO:0030165	PDZ domain binding
0.79	GO:0031625	ubiquitin protein ligase binding
0.78	GO:0008022	protein C-terminus binding
0.78	GO:0019900	kinase binding
0.75	GO:0004385	guanylate kinase activity
0.60	GO:0015276	ligand-gated ion channel activity

0.86	GO:0032281	AMPA glutamate receptor complex
0.82	GO:0043198	dendritic shaft
0.81	GO:0005923	bicellular tight junction
0.79	GO:0030426	growth cone
0.79	GO:0014069	postsynaptic density
0.77	GO:0016323	basolateral plasma membrane
0.76	GO:0043025	neuronal cell body
0.75	GO:0045211	postsynaptic membrane
0.64	GO:0005615	extracellular space
0.56	GO:0005829	cytosol

0.75

EC:2.7.4.8

GO:0004385

tr|T1G7L2|T1G7L2_HELRO
Ribosome biogenesis protein BOP1 homolog
Search

BOP1

0.83	Ribosome biogenesis protein bop1-A

0.77	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.75	GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.48	GO:1901796	regulation of signal transduction by p53 class mediator
0.48	GO:0000479	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.46	GO:0008283	cell proliferation
0.46	GO:0051726	regulation of cell cycle
0.45	GO:0000027	ribosomal large subunit assembly
0.43	GO:0035206	regulation of hemocyte proliferation
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.69	GO:0043021	ribonucleoprotein complex binding
0.35	GO:0070180	large ribosomal subunit rRNA binding
0.34	GO:0005515	protein binding
0.33	GO:0043565	sequence-specific DNA binding
0.33	GO:0003700	DNA binding transcription factor activity

0.75	GO:0030687	preribosome, large subunit precursor
0.72	GO:0005730	nucleolus
0.69	GO:0005654	nucleoplasm
0.52	GO:0030686	90S preribosome
0.43	GO:0043234	protein complex
0.30	GO:0016020	membrane

tr|T1G7L3|T1G7L3_HELRO
Uncharacterized protein
Search

IMP4

0.78	U3 small nucleolar ribonucleoprotein snornp component

0.47	GO:0006364	rRNA processing
0.41	GO:0042274	ribosomal small subunit biogenesis
0.34	GO:0000387	spliceosomal snRNP assembly
0.33	GO:0006357	regulation of transcription by RNA polymerase II
0.32	GO:0055114	oxidation-reduction process
0.32	GO:0007165	signal transduction

0.56	GO:0042134	rRNA primary transcript binding
0.53	GO:0030515	snoRNA binding
0.43	GO:0043047	single-stranded telomeric DNA binding
0.36	GO:0030519	snoRNP binding
0.35	GO:0016787	hydrolase activity
0.34	GO:0001104	RNA polymerase II transcription cofactor activity
0.33	GO:0005509	calcium ion binding
0.33	GO:0010181	FMN binding
0.33	GO:0005515	protein binding
0.33	GO:0016491	oxidoreductase activity

0.60	GO:0019013	viral nucleocapsid
0.56	GO:0030529	intracellular ribonucleoprotein complex
0.55	GO:0044452	nucleolar part
0.43	GO:0043234	protein complex
0.34	GO:0005654	nucleoplasm
0.34	GO:0016363	nuclear matrix
0.30	GO:0016020	membrane

0.35

GO:0016787

tr|T1G7L4|T1G7L4_HELRO
Uncharacterized protein
Search

0.75	Dorsal root ganglia homeobox protein (Fragment)

0.53	GO:1903506	regulation of nucleic acid-templated transcription
0.53	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.53	GO:0007275	multicellular organism development
0.52	GO:0010468	regulation of gene expression
0.46	GO:0007601	visual perception
0.46	GO:0006366	transcription by RNA polymerase II
0.35	GO:1902680	positive regulation of RNA biosynthetic process

0.59	GO:0043565	sequence-specific DNA binding
0.41	GO:0003700	DNA binding transcription factor activity
0.35	GO:0001012	RNA polymerase II regulatory region DNA binding
0.35	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|T1G7L5|T1G7L5_HELRO
Uncharacterized protein
Search

0.37	DNA-directed RNA polymerase beta subunit

0.44	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.42	GO:0007528	neuromuscular junction development
0.42	GO:0006508	proteolysis
0.39	GO:0032836	glomerular basement membrane development
0.39	GO:0051972	regulation of telomerase activity
0.39	GO:0008219	cell death
0.39	GO:0007155	cell adhesion
0.38	GO:0006471	protein ADP-ribosylation
0.38	GO:0006954	inflammatory response
0.37	GO:0006032	chitin catabolic process

0.59	GO:0005201	extracellular matrix structural constituent
0.42	GO:0008233	peptidase activity
0.39	GO:0005515	protein binding
0.38	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.38	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.37	GO:0044877	macromolecular complex binding
0.37	GO:0004568	chitinase activity
0.37	GO:0005199	structural constituent of cell wall
0.36	GO:0004420	hydroxymethylglutaryl-CoA reductase (NADPH) activity
0.36	GO:0030246	carbohydrate binding

0.59	GO:0005604	basement membrane
0.57	GO:0005581	collagen trimer
0.46	GO:0098645	collagen network
0.42	GO:0031594	neuromuscular junction
0.42	GO:0005618	cell wall
0.39	GO:0019867	outer membrane
0.38	GO:0005876	spindle microtubule
0.36	GO:0005829	cytosol
0.36	GO:0005883	neurofilament
0.34	GO:0005783	endoplasmic reticulum

0.42	EC:3.4	GO:0008233
0.36	KEGG:R02082	GO:0004420

tr|T1G7L6|T1G7L6_HELRO
Uncharacterized protein
Search

0.10	ATP-binding cassette sub-family A member 7-like

0.54	GO:0055085	transmembrane transport
0.53	GO:0006869	lipid transport
0.49	GO:0007601	visual perception
0.48	GO:0097035	regulation of membrane lipid distribution
0.47	GO:0045494	photoreceptor cell maintenance
0.47	GO:0015748	organophosphate ester transport
0.44	GO:0015711	organic anion transport
0.43	GO:0038027	apolipoprotein A-I-mediated signaling pathway
0.42	GO:0034380	high-density lipoprotein particle assembly
0.40	GO:0015850	organic hydroxy compound transport

0.65	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.50	GO:0090555	phosphatidylethanolamine-translocating ATPase activity
0.43	GO:0090556	phosphatidylserine-translocating ATPase activity
0.43	GO:0034188	apolipoprotein A-I receptor activity
0.43	GO:0090554	phosphatidylcholine-translocating ATPase activity
0.35	GO:0005516	calmodulin binding

0.47	GO:0001750	photoreceptor outer segment
0.45	GO:0005887	integral component of plasma membrane
0.43	GO:0097233	alveolar lamellar body membrane
0.40	GO:0043231	intracellular membrane-bounded organelle
0.39	GO:0030054	cell junction
0.35	GO:0031253	cell projection membrane
0.34	GO:0001891	phagocytic cup
0.34	GO:0031901	early endosome membrane
0.34	GO:0031256	leading edge membrane
0.34	GO:0001726	ruffle

tr|T1G7L7|T1G7L7_HELRO
Uncharacterized protein
Search

0.59	GO:0006518	peptide metabolic process
0.52	GO:0055114	oxidation-reduction process
0.38	GO:0044719	regulation of imaginal disc-derived wing size
0.37	GO:0007613	memory
0.37	GO:0009620	response to fungus
0.34	GO:0010951	negative regulation of endopeptidase activity
0.32	GO:0032504	multicellular organism reproduction
0.32	GO:0006468	protein phosphorylation

0.83	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
0.70	GO:0005507	copper ion binding
0.40	GO:0004598	peptidylamidoglycolate lyase activity
0.35	GO:0008270	zinc ion binding
0.35	GO:0004867	serine-type endopeptidase inhibitor activity
0.33	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.32	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.33	GO:0005576	extracellular region
0.33	GO:0043025	neuronal cell body
0.30	GO:0016020	membrane

0.83

EC:1.14.17

GO:0016715

tr|T1G7L8|T1G7L8_HELRO
Uncharacterized protein
Search

EXOSC3

0.73	Exosome component 3

0.48	GO:0071038	nuclear polyadenylation-dependent tRNA catabolic process
0.48	GO:0000467	exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.48	GO:0071035	nuclear polyadenylation-dependent rRNA catabolic process
0.46	GO:0071049	nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription
0.46	GO:0071034	CUT catabolic process
0.46	GO:0071051	polyadenylation-dependent snoRNA 3'-end processing
0.45	GO:0034475	U4 snRNA 3'-end processing
0.45	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
0.45	GO:0034427	nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'
0.43	GO:0021693	cerebellar Purkinje cell layer structural organization

0.59	GO:0003723	RNA binding
0.38	GO:0004527	exonuclease activity
0.37	GO:0030145	manganese ion binding
0.36	GO:0015217	ADP transmembrane transporter activity
0.36	GO:0005347	ATP transmembrane transporter activity

0.79	GO:0000178	exosome (RNase complex)
0.42	GO:0031981	nuclear lumen
0.38	GO:0044444	cytoplasmic part
0.34	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1G7L9|T1G7L9_HELRO
Uncharacterized protein
Search

MSRB

0.44	Methionine-R-sulfoxide reductase B2, mitochondrial (inferred by orthology to a human protein)

0.77	GO:0030091	protein repair
0.71	GO:0006979	response to oxidative stress
0.53	GO:0055114	oxidation-reduction process

0.79

GO:0033743

peptide-methionine (R)-S-oxide reductase activity

0.79	EC:1.8.4 EC:1.8.4.12	GO:0033743
0.79	KEGG:R07607	GO:0033743

tr|T1G7M0|T1G7M0_HELRO
Uncharacterized protein
Search

0.46	Peptidyl-alpha-hydroxyglycine alpha-amidating lyase

0.59	GO:0006518	peptide metabolic process
0.49	GO:0055114	oxidation-reduction process
0.39	GO:0018032	protein amidation
0.38	GO:0007595	lactation
0.37	GO:0060135	maternal process involved in female pregnancy
0.37	GO:0032355	response to estradiol
0.37	GO:0051384	response to glucocorticoid
0.37	GO:0042476	odontogenesis
0.37	GO:0022602	ovulation cycle process
0.37	GO:0009268	response to pH

0.75	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
0.63	GO:0005507	copper ion binding
0.53	GO:0004598	peptidylamidoglycolate lyase activity
0.42	GO:0008270	zinc ion binding
0.37	GO:0031418	L-ascorbic acid binding
0.36	GO:0019901	protein kinase binding
0.35	GO:0005509	calcium ion binding

0.38	GO:0030659	cytoplasmic vesicle membrane
0.37	GO:0043204	perikaryon
0.37	GO:0098805	whole membrane
0.37	GO:0098588	bounding membrane of organelle
0.37	GO:0030141	secretory granule
0.36	GO:0005802	trans-Golgi network
0.36	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0043005	neuron projection
0.36	GO:0030133	transport vesicle
0.36	GO:0009986	cell surface

0.75

EC:1.14.17

GO:0016715

tr|T1G7M1|T1G7M1_HELRO
Uncharacterized protein
Search

ABHD17B

0.83	Alpha/beta hydrolase domain-containing protein 17C

0.62	GO:1902816	regulation of protein localization to microtubule
0.61	GO:0098734	macromolecule depalmitoylation
0.61	GO:1902473	regulation of protein localization to synapse
0.61	GO:1905668	positive regulation of protein localization to endosome
0.60	GO:0018345	protein palmitoylation
0.60	GO:1902950	regulation of dendritic spine maintenance
0.58	GO:0042159	lipoprotein catabolic process
0.57	GO:1903828	negative regulation of cellular protein localization
0.54	GO:0035601	protein deacylation
0.42	GO:0042595	behavioral response to starvation

0.61	GO:0008474	palmitoyl-(protein) hydrolase activity
0.38	GO:0008236	serine-type peptidase activity
0.33	GO:0005515	protein binding

0.58	GO:0055038	recycling endosome membrane
0.57	GO:0014069	postsynaptic density
0.43	GO:0005886	plasma membrane
0.42	GO:0071683	sensory dendrite
0.37	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.61

EC:3.1.2.22

GO:0008474

tr|T1G7M2|T1G7M2_HELRO
Uncharacterized protein
Search

BRU-3

0.85	Bruno-3 transcript variant 5

0.37	GO:0017148	negative regulation of translation
0.37	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.36	GO:0071625	vocalization behavior
0.35	GO:0006397	mRNA processing
0.34	GO:0001505	regulation of neurotransmitter levels
0.32	GO:2001141	regulation of RNA biosynthetic process

0.59	GO:0003723	RNA binding
0.38	GO:0042803	protein homodimerization activity
0.34	GO:0003713	transcription coactivator activity
0.33	GO:0008270	zinc ion binding
0.32	GO:0003677	DNA binding

0.36	GO:0043234	protein complex
0.34	GO:0005634	nucleus
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|T1G7M3|T1G7M3_HELRO
Uncharacterized protein
Search

0.61	GO:0006508	proteolysis
0.35	GO:0007218	neuropeptide signaling pathway

0.70	GO:0004222	metalloendopeptidase activity
0.32	GO:0046872	metal ion binding

0.33	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.70

GO:0004222

tr|T1G7M4|T1G7M4_HELRO
Uncharacterized protein
Search

0.42	troponin C, skeletal muscle

0.39	GO:0006468	protein phosphorylation
0.36	GO:0019722	calcium-mediated signaling
0.36	GO:0009737	response to abscisic acid
0.36	GO:0009414	response to water deprivation
0.36	GO:0009651	response to salt stress
0.35	GO:0003009	skeletal muscle contraction
0.34	GO:0006937	regulation of muscle contraction
0.34	GO:1903087	mitotic spindle pole body duplication
0.33	GO:0022027	interkinetic nuclear migration
0.33	GO:0051301	cell division

0.70	GO:0005509	calcium ion binding
0.39	GO:0004683	calmodulin-dependent protein kinase activity
0.37	GO:0030554	adenyl nucleotide binding
0.36	GO:0097367	carbohydrate derivative binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.35	GO:0048306	calcium-dependent protein binding
0.34	GO:0051015	actin filament binding
0.34	GO:2001070	starch binding

0.35	GO:0005856	cytoskeleton
0.35	GO:0005829	cytosol
0.34	GO:0036379	myofilament
0.34	GO:0005634	nucleus
0.34	GO:0030017	sarcomere
0.34	GO:0044446	intracellular organelle part
0.33	GO:0044815	DNA packaging complex
0.33	GO:0032993	protein-DNA complex
0.33	GO:0005694	chromosome
0.33	GO:0043234	protein complex

0.39

EC:2.7.11.17

GO:0004683

tr|T1G7M5|T1G7M5_HELRO
Uncharacterized protein
Search

0.55	COX assembly mitochondrial protein (Fragment)

0.61

GO:0005739

mitochondrion

tr|T1G7M6|T1G7M6_HELRO
Uncharacterized protein
Search

0.59	Putative syntaxin-binding protein 2 (Fragment)

0.36	GO:0065007	biological regulation
0.35	GO:0006511	ubiquitin-dependent protein catabolic process
0.35	GO:0023052	signaling
0.35	GO:0036211	protein modification process
0.35	GO:0032511	late endosome to vacuole transport via multivesicular body sorting pathway
0.35	GO:0072666	establishment of protein localization to vacuole
0.35	GO:0051716	cellular response to stimulus
0.35	GO:0007154	cell communication
0.35	GO:0016310	phosphorylation
0.34	GO:0048208	COPII vesicle coating

0.37	GO:0005070	SH3/SH2 adaptor activity
0.36	GO:0005509	calcium ion binding
0.36	GO:0004674	protein serine/threonine kinase activity
0.35	GO:0030234	enzyme regulator activity
0.35	GO:0046983	protein dimerization activity
0.34	GO:0017154	semaphorin receptor activity
0.34	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.34	GO:0004333	fumarate hydratase activity
0.34	GO:0061630	ubiquitin protein ligase activity
0.34	GO:0003951	NAD+ kinase activity

0.35	GO:0045095	keratin filament
0.35	GO:0000814	ESCRT II complex
0.35	GO:0005634	nucleus
0.34	GO:0045239	tricarboxylic acid cycle enzyme complex
0.34	GO:0000139	Golgi membrane
0.33	GO:0005581	collagen trimer
0.33	GO:0005783	endoplasmic reticulum
0.30	GO:0016021	integral component of membrane

0.36	EC:2.7.11	GO:0004674
0.34	KEGG:R01082	GO:0004333

tr|T1G7M8|T1G7M8_HELRO
Uncharacterized protein
Search

0.90	Putative HAT, C-terminal dimerization domain-containing protein

0.68

GO:0046983

protein dimerization activity

tr|T1G7M9|T1G7M9_HELRO
Uncharacterized protein
Search

ISCU

0.47	Iron-sulfur cluster assembly enzyme ISCU

0.74	GO:0016226	iron-sulfur cluster assembly
0.41	GO:0097428	protein maturation by iron-sulfur cluster transfer
0.40	GO:0006879	cellular iron ion homeostasis
0.33	GO:0055085	transmembrane transport

0.64	GO:0051536	iron-sulfur cluster binding
0.63	GO:0005506	iron ion binding
0.44	GO:0036455	iron-sulfur transferase activity
0.40	GO:0003677	DNA binding

0.49	GO:0005759	mitochondrial matrix
0.43	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

tr|T1G7N0|T1G7N0_HELRO
Uncharacterized protein
Search

0.64	Gamma-aminobutyric acid receptor subunit beta

0.61	GO:0007165	signal transduction
0.60	GO:0034220	ion transmembrane transport
0.49	GO:0006821	chloride transport
0.49	GO:0060078	regulation of postsynaptic membrane potential
0.48	GO:0007268	chemical synaptic transmission
0.47	GO:0097112	gamma-aminobutyric acid receptor clustering
0.46	GO:0060013	righting reflex
0.46	GO:0001964	startle response
0.46	GO:0007628	adult walking behavior
0.45	GO:0007340	acrosome reaction

0.75	GO:0005230	extracellular ligand-gated ion channel activity
0.70	GO:0004888	transmembrane signaling receptor activity
0.52	GO:0099095	ligand-gated anion channel activity
0.49	GO:0005254	chloride channel activity
0.46	GO:0016594	glycine binding
0.33	GO:0005515	protein binding
0.33	GO:0008199	ferric iron binding
0.33	GO:0022835	transmitter-gated channel activity

0.55	GO:0005886	plasma membrane
0.49	GO:0098794	postsynapse
0.47	GO:0098982	GABA-ergic synapse
0.44	GO:0034707	chloride channel complex
0.35	GO:0030054	cell junction
0.35	GO:0030425	dendrite
0.35	GO:0031594	neuromuscular junction
0.35	GO:1902711	GABA-A receptor complex
0.34	GO:0043204	perikaryon
0.33	GO:0009986	cell surface

tr|T1G7N1|T1G7N1_HELRO
Uncharacterized protein
Search

tr|T1G7N2|T1G7N2_HELRO
Uncharacterized protein
Search

0.10	Transcription factor HIVEP2 (Fragment)

0.46	GO:0048100	wing disc anterior/posterior pattern formation
0.45	GO:0000122	negative regulation of transcription by RNA polymerase II
0.45	GO:0007494	midgut development
0.45	GO:0007443	Malpighian tubule morphogenesis
0.45	GO:0048190	wing disc dorsal/ventral pattern formation
0.45	GO:0008586	imaginal disc-derived wing vein morphogenesis
0.45	GO:0007398	ectoderm development
0.44	GO:0006366	transcription by RNA polymerase II
0.44	GO:0048813	dendrite morphogenesis
0.43	GO:0008283	cell proliferation

0.51	GO:0003676	nucleic acid binding
0.51	GO:0008270	zinc ion binding
0.48	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.44	GO:0001105	RNA polymerase II transcription coactivator activity
0.44	GO:0001102	RNA polymerase II activating transcription factor binding
0.40	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.34	GO:0004713	protein tyrosine kinase activity
0.33	GO:0016758	transferase activity, transferring hexosyl groups
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding

0.41	GO:0005634	nucleus
0.35	GO:0043233	organelle lumen
0.34	GO:0005739	mitochondrion
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.34

GO:0004713

tr|T1G7N3|T1G7N3_HELRO
Uncharacterized protein
Search

IFA-1

0.90	Intermediate filament gliarin

0.37	GO:0097284	hepatocyte apoptotic process
0.37	GO:0033209	tumor necrosis factor-mediated signaling pathway
0.37	GO:0097191	extrinsic apoptotic signaling pathway
0.36	GO:0060706	cell differentiation involved in embryonic placenta development
0.35	GO:0048468	cell development
0.35	GO:0043207	response to external biotic stimulus
0.35	GO:0051599	response to hydrostatic pressure
0.34	GO:0030182	neuron differentiation
0.34	GO:0120036	plasma membrane bounded cell projection organization
0.34	GO:0051704	multi-organism process

0.62	GO:0005198	structural molecule activity
0.37	GO:0097110	scaffold protein binding
0.33	GO:0032403	protein complex binding
0.33	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.33	GO:0097506	deaminated base DNA N-glycosylase activity
0.32	GO:0042626	ATPase activity, coupled to transmembrane movement of substances

0.79	GO:0005882	intermediate filament
0.37	GO:0016327	apicolateral plasma membrane
0.36	GO:0042383	sarcolemma
0.36	GO:0030018	Z disc
0.36	GO:0005911	cell-cell junction
0.35	GO:0016363	nuclear matrix
0.34	GO:0043034	costamere
0.34	GO:0005654	nucleoplasm
0.34	GO:0016010	dystrophin-associated glycoprotein complex
0.34	GO:0070062	extracellular exosome

0.33

GO:0032440

tr|T1G7N4|T1G7N4_HELRO
Uncharacterized protein
Search

MCOLN1

0.86	Transient receptor potential ML

0.50	GO:0051259	protein oligomerization
0.50	GO:0071277	cellular response to calcium ion
0.50	GO:0097352	autophagosome maturation
0.49	GO:0071467	cellular response to pH
0.49	GO:0071642	positive regulation of macrophage inflammatory protein 1 alpha production
0.49	GO:0035926	chemokine (C-C motif) ligand 2 secretion
0.49	GO:0019722	calcium-mediated signaling
0.49	GO:0071651	positive regulation of chemokine (C-C motif) ligand 5 production
0.49	GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production
0.48	GO:0071639	positive regulation of monocyte chemotactic protein-1 production

0.53	GO:0097682	intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity
0.49	GO:0099604	ligand-gated calcium channel activity
0.36	GO:0008289	lipid binding
0.34	GO:0005249	voltage-gated potassium channel activity
0.34	GO:0005230	extracellular ligand-gated ion channel activity
0.34	GO:0005381	iron ion transmembrane transporter activity
0.34	GO:0005515	protein binding
0.34	GO:0003777	microtubule motor activity
0.34	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.32	GO:0030554	adenyl nucleotide binding

0.51	GO:0005768	endosome
0.49	GO:0005764	lysosome
0.47	GO:0043235	receptor complex
0.44	GO:0005829	cytosol
0.40	GO:0005886	plasma membrane
0.39	GO:0098852	lytic vacuole membrane
0.38	GO:0030670	phagocytic vesicle membrane
0.35	GO:0042995	cell projection
0.30	GO:0016021	integral component of membrane

0.34

EC:5.2.1.8

GO:0003755

tr|T1G7N5|T1G7N5_HELRO
Uncharacterized protein
Search

ORAI1

0.85	Calcium release-activated calcium channel protein 1

0.54	GO:0002115	store-operated calcium entry
0.48	GO:0070509	calcium ion import
0.47	GO:0061180	mammary gland epithelium development
0.44	GO:0070588	calcium ion transmembrane transport
0.39	GO:0051928	positive regulation of calcium ion transport
0.38	GO:0002250	adaptive immune response
0.35	GO:0051533	positive regulation of NFAT protein import into nucleus
0.34	GO:0045214	sarcomere organization
0.34	GO:0007399	nervous system development

0.48	GO:0015279	store-operated calcium channel activity
0.36	GO:0042802	identical protein binding
0.36	GO:0005516	calmodulin binding
0.33	GO:0016787	hydrolase activity

0.47	GO:0016323	basolateral plasma membrane
0.42	GO:0005829	cytosol
0.40	GO:0043234	protein complex
0.36	GO:0005887	integral component of plasma membrane
0.35	GO:0005776	autophagosome
0.34	GO:0031410	cytoplasmic vesicle
0.34	GO:0030426	growth cone

0.33

GO:0016787

tr|T1G7N6|T1G7N6_HELRO
Uncharacterized protein
Search

0.83	Voltage-gated potassium channel subunit beta-1

0.72	GO:0071805	potassium ion transmembrane transport
0.46	GO:0050802	circadian sleep/wake cycle, sleep
0.45	GO:0045938	positive regulation of circadian sleep/wake cycle, sleep
0.42	GO:0065009	regulation of molecular function
0.41	GO:0034765	regulation of ion transmembrane transport
0.41	GO:0051259	protein oligomerization
0.41	GO:0043266	regulation of potassium ion transport
0.39	GO:0002244	hematopoietic progenitor cell differentiation
0.39	GO:0050905	neuromuscular process
0.39	GO:0070995	NADPH oxidation

0.77	GO:0005249	voltage-gated potassium channel activity
0.49	GO:0015459	potassium channel regulator activity
0.38	GO:0004033	aldo-keto reductase (NADP) activity
0.35	GO:0005515	protein binding
0.34	GO:0070402	NADPH binding

0.48	GO:0005737	cytoplasm
0.45	GO:0008076	voltage-gated potassium channel complex
0.40	GO:0044224	juxtaparanode region of axon
0.39	GO:0043679	axon terminus
0.39	GO:0014069	postsynaptic density
0.38	GO:1990031	pinceau fiber
0.37	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.36	GO:0030054	cell junction
0.36	GO:0005874	microtubule
0.34	GO:0030008	TRAPP complex

0.38

EC:1.1.1

GO:0004033

tr|T1G7N7|T1G7N7_HELRO
Uncharacterized protein
Search

tr|T1G7N8|T1G7N8_HELRO
Uncharacterized protein
Search

0.86	Coronin, actin binding protein, 2A

0.60	GO:0030036	actin cytoskeleton organization
0.58	GO:0001845	phagolysosome assembly
0.56	GO:0030595	leukocyte chemotaxis
0.47	GO:0061502	early endosome to recycling endosome transport
0.47	GO:0032796	uropod organization
0.47	GO:0038180	nerve growth factor signaling pathway
0.47	GO:0043320	natural killer cell degranulation
0.46	GO:0031339	negative regulation of vesicle fusion
0.46	GO:0071353	cellular response to interleukin-4
0.46	GO:0048873	homeostasis of number of cells within a tissue

0.75	GO:0051015	actin filament binding
0.46	GO:0032036	myosin heavy chain binding
0.45	GO:0043548	phosphatidylinositol 3-kinase binding
0.45	GO:0003785	actin monomer binding
0.44	GO:0008022	protein C-terminus binding
0.42	GO:0042803	protein homodimerization activity
0.35	GO:0048365	Rac GTPase binding
0.33	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.33	GO:0004725	protein tyrosine phosphatase activity
0.33	GO:0008289	lipid binding

0.60	GO:0015629	actin cytoskeleton
0.58	GO:0017053	transcriptional repressor complex
0.45	GO:0001772	immunological synapse
0.45	GO:0001891	phagocytic cup
0.45	GO:0030027	lamellipodium
0.45	GO:0045335	phagocytic vesicle
0.44	GO:0005769	early endosome
0.44	GO:0030424	axon
0.43	GO:0030863	cortical cytoskeleton
0.43	GO:0005911	cell-cell junction

0.33

GO:0008138

tr|T1G7N9|T1G7N9_HELRO
Uncharacterized protein
Search

0.80	GO:0048149	behavioral response to ethanol
0.78	GO:0035264	multicellular organism growth

0.30

GO:0044425

membrane part

tr|T1G7P0|T1G7P0_HELRO
Coronin
Search

0.46

Coronin

0.58	GO:0030036	actin cytoskeleton organization
0.57	GO:1902463	protein localization to cell leading edge
0.57	GO:0071672	negative regulation of smooth muscle cell chemotaxis
0.56	GO:2000394	positive regulation of lamellipodium morphogenesis
0.55	GO:0036120	cellular response to platelet-derived growth factor stimulus
0.55	GO:0035767	endothelial cell chemotaxis
0.54	GO:0031529	ruffle organization
0.54	GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation
0.51	GO:0042060	wound healing
0.48	GO:0097435	supramolecular fiber organization

0.70	GO:0051015	actin filament binding
0.54	GO:0071933	Arp2/3 complex binding
0.52	GO:0045296	cadherin binding
0.48	GO:0042802	identical protein binding
0.34	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives
0.33	GO:0016746	transferase activity, transferring acyl groups
0.32	GO:0016301	kinase activity

0.56	GO:0017053	transcriptional repressor complex
0.54	GO:0015629	actin cytoskeleton
0.52	GO:0030027	lamellipodium
0.51	GO:0048471	perinuclear region of cytoplasm
0.49	GO:0044430	cytoskeletal part
0.48	GO:0099512	supramolecular fiber
0.46	GO:0005829	cytosol
0.44	GO:0035838	growing cell tip
0.44	GO:0070938	contractile ring
0.43	GO:0043332	mating projection tip

0.34

EC:5.1.3

GO:0016857

tr|T1G7P1|T1G7P1_HELRO
Uncharacterized protein
Search

0.75	GO:0007286	spermatid development
0.72	GO:0060548	negative regulation of cell death
0.45	GO:0034620	cellular response to unfolded protein
0.30	GO:0008152	metabolic process

0.79	GO:0051879	Hsp90 protein binding
0.79	GO:0030544	Hsp70 protein binding
0.79	GO:0043014	alpha-tubulin binding
0.76	GO:0048487	beta-tubulin binding
0.73	GO:0001664	G-protein coupled receptor binding
0.73	GO:0031625	ubiquitin protein ligase binding
0.70	GO:0051087	chaperone binding
0.67	GO:0003779	actin binding
0.35	GO:0046872	metal ion binding
0.34	GO:0016740	transferase activity

0.80	GO:0097225	sperm midpiece
0.73	GO:0044297	cell body
0.71	GO:0043005	neuron projection
0.66	GO:0031982	vesicle
0.63	GO:0005829	cytosol
0.56	GO:0005739	mitochondrion
0.39	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0016740

tr|T1G7P2|T1G7P2_HELRO
Uncharacterized protein
Search

0.97	GDP-D-glucose phosphorylase

0.44	GO:0006006	glucose metabolic process
0.35	GO:0065009	regulation of molecular function
0.34	GO:0006351	transcription, DNA-templated
0.34	GO:2001141	regulation of RNA biosynthetic process
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression

0.85	GO:0080048	GDP-D-glucose phosphorylase activity
0.36	GO:0005085	guanyl-nucleotide exchange factor activity
0.35	GO:0016779	nucleotidyltransferase activity
0.34	GO:0003677	DNA binding
0.33	GO:1901265	nucleoside phosphate binding
0.33	GO:0036094	small molecule binding
0.33	GO:0016787	hydrolase activity

0.36	GO:0005737	cytoplasm
0.35	GO:0005856	cytoskeleton
0.34	GO:0005634	nucleus

0.35

EC:2.7.7

GO:0016779

tr|T1G7P3|T1G7P3_HELRO
Uncharacterized protein
Search

0.11	Unc-79 homolog, NALCN channel complex subunit

0.86	GO:0048149	behavioral response to ethanol
0.85	GO:0035264	multicellular organism growth

tr|T1G7P4|T1G7P4_HELRO
Uncharacterized protein
Search

RIBC2

0.93	RIB43A domain with coiled coils 1

0.47	GO:0010952	positive regulation of peptidase activity
0.46	GO:0030198	extracellular matrix organization

0.47	GO:0005509	calcium ion binding
0.47	GO:0016504	peptidase activator activity
0.45	GO:0005515	protein binding
0.39	GO:0045735	nutrient reservoir activity

0.48	GO:0005634	nucleus
0.46	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

tr|T1G7P5|T1G7P5_HELRO
Uncharacterized protein
Search

CCDC25

0.61	Coiled-coil domain-containing protein 25

0.41	GO:0019538	protein metabolic process
0.40	GO:0006355	regulation of transcription, DNA-templated
0.39	GO:0043043	peptide biosynthetic process
0.37	GO:0010467	gene expression
0.37	GO:0009059	macromolecule biosynthetic process
0.36	GO:0044260	cellular macromolecule metabolic process

0.48	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.40	GO:0003735	structural constituent of ribosome
0.39	GO:0003677	DNA binding

0.48	GO:0070062	extracellular exosome
0.40	GO:0005840	ribosome
0.30	GO:0016020	membrane

tr|T1G7P6|T1G7P6_HELRO
Uncharacterized protein
Search

0.51	GO:0006468	protein phosphorylation
0.45	GO:0006915	apoptotic process
0.41	GO:0016567	protein ubiquitination
0.40	GO:0034220	ion transmembrane transport
0.40	GO:0009116	nucleoside metabolic process
0.40	GO:0042391	regulation of membrane potential
0.39	GO:0071804	cellular potassium ion transport
0.38	GO:0007165	signal transduction
0.37	GO:0006629	lipid metabolic process

0.51	GO:0004672	protein kinase activity
0.45	GO:0032559	adenyl ribonucleotide binding
0.44	GO:0008144	drug binding
0.44	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0005216	ion channel activity
0.42	GO:0005515	protein binding
0.39	GO:0008081	phosphoric diester hydrolase activity
0.39	GO:0022832	voltage-gated channel activity
0.39	GO:0015079	potassium ion transmembrane transporter activity
0.38	GO:0004842	ubiquitin-protein transferase activity

0.39	GO:0000151	ubiquitin ligase complex
0.38	GO:0005887	integral component of plasma membrane
0.36	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm

0.39	EC:3.1.4	GO:0008081
0.38	KEGG:R03876	GO:0004842

tr|T1G7P7|T1G7P7_HELRO
Uncharacterized protein
Search

HSPA12A

0.85	Heat shock protein 12A

0.50	GO:0030554	adenyl nucleotide binding
0.49	GO:0097367	carbohydrate derivative binding
0.49	GO:0008144	drug binding
0.49	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0005515	protein binding

0.59	GO:0070062	extracellular exosome
0.30	GO:0044425	membrane part

tr|T1G7P8|T1G7P8_HELRO
Uncharacterized protein
Search

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process

0.64	GO:0003735	structural constituent of ribosome
0.36	GO:0003723	RNA binding

0.61	GO:0005840	ribosome
0.40	GO:0044445	cytosolic part
0.37	GO:0005844	polysome
0.37	GO:0044446	intracellular organelle part
0.33	GO:0005783	endoplasmic reticulum
0.33	GO:0043233	organelle lumen
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

tr|T1G7P9|T1G7P9_HELRO
Uncharacterized protein
Search

0.65	Solute carrier family 15 (Oligopeptide transporter) member 1

0.77	GO:0006857	oligopeptide transport
0.55	GO:0055085	transmembrane transport
0.40	GO:0015992	proton transport
0.37	GO:2000192	negative regulation of fatty acid transport
0.36	GO:0040010	positive regulation of growth rate
0.36	GO:0080144	amino acid homeostasis
0.36	GO:1900101	regulation of endoplasmic reticulum unfolded protein response
0.36	GO:0040018	positive regulation of multicellular organism growth
0.36	GO:0002119	nematode larval development
0.36	GO:0008340	determination of adult lifespan

0.57	GO:0022857	transmembrane transporter activity
0.47	GO:0042936	dipeptide transporter activity
0.35	GO:0004035	alkaline phosphatase activity
0.33	GO:0043492	ATPase activity, coupled to movement of substances

0.35	GO:0016324	apical plasma membrane
0.35	GO:0030670	phagocytic vesicle membrane
0.34	GO:0009705	plant-type vacuole membrane
0.33	GO:0005887	integral component of plasma membrane

0.35

EC:3.1.3.1

GO:0004035

tr|T1G7Q0|T1G7Q0_HELRO
Uncharacterized protein
Search

BMI1

0.80	polycomb group RING finger protein 6-like

0.77	GO:0033092	positive regulation of immature T cell proliferation in thymus
0.77	GO:2000011	regulation of adaxial/abaxial pattern formation
0.73	GO:0021903	rostrocaudal neural tube patterning
0.72	GO:0030890	positive regulation of B cell proliferation
0.72	GO:0048103	somatic stem cell division
0.71	GO:0016574	histone ubiquitination
0.70	GO:0048704	embryonic skeletal system morphogenesis
0.69	GO:2001234	negative regulation of apoptotic signaling pathway
0.68	GO:0006959	humoral immune response
0.67	GO:0007420	brain development

0.75	GO:1990841	promoter-specific chromatin binding
0.69	GO:0097027	ubiquitin-protein transferase activator activity
0.67	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.47	GO:0046872	metal ion binding
0.44	GO:0071535	RING-like zinc finger domain binding

0.73	GO:0031519	PcG protein complex
0.68	GO:0000792	heterochromatin
0.67	GO:0016604	nuclear body
0.66	GO:0000151	ubiquitin ligase complex
0.38	GO:0005829	cytosol

tr|T1G7Q1|T1G7Q1_HELRO
Uncharacterized protein
Search

0.74	GO:0007015	actin filament organization
0.47	GO:0007155	cell adhesion
0.38	GO:0006897	endocytosis

0.30

GO:0044425

membrane part

tr|T1G7Q2|T1G7Q2_HELRO
Uncharacterized protein
Search

EMG1

0.68	rRNA small subunit pseudouridine methyltransferase Nep1

0.63	GO:0032259	methylation
0.57	GO:0017126	nucleologenesis
0.52	GO:0001824	blastocyst development
0.47	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.44	GO:0000154	rRNA modification
0.41	GO:0042742	defense response to bacterium
0.36	GO:0044260	cellular macromolecule metabolic process
0.33	GO:0006508	proteolysis

0.63	GO:0008168	methyltransferase activity
0.44	GO:0140102	catalytic activity, acting on a rRNA
0.42	GO:0019843	rRNA binding
0.33	GO:0004252	serine-type endopeptidase activity
0.33	GO:0005515	protein binding

0.46	GO:0032040	small-subunit processome
0.44	GO:0005730	nucleolus
0.33	GO:0005654	nucleoplasm
0.32	GO:0005737	cytoplasm

0.63

GO:0008168

tr|T1G7Q3|T1G7Q3_HELRO
Uncharacterized protein
Search

0.77	GO:0006857	oligopeptide transport
0.55	GO:0055085	transmembrane transport
0.35	GO:0015992	proton transport
0.33	GO:0016311	dephosphorylation
0.33	GO:0015031	protein transport

0.57	GO:0022857	transmembrane transporter activity
0.41	GO:0015197	peptide transporter activity
0.34	GO:0004035	alkaline phosphatase activity
0.32	GO:0043492	ATPase activity, coupled to movement of substances

0.35	GO:0030670	phagocytic vesicle membrane
0.33	GO:0005887	integral component of plasma membrane

0.34

EC:3.1.3.1

GO:0004035

tr|T1G7Q4|T1G7Q4_HELRO
Uncharacterized protein
Search

0.77	Protein phosphatase 1 regulatory inhibitor subunit 16B

0.75	GO:0043666	regulation of phosphoprotein phosphatase activity
0.58	GO:1902309	negative regulation of peptidyl-serine dephosphorylation
0.57	GO:1903589	positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis
0.55	GO:0061028	establishment of endothelial barrier
0.54	GO:0035307	positive regulation of protein dephosphorylation
0.54	GO:0014066	regulation of phosphatidylinositol 3-kinase signaling
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression
0.33	GO:0035335	peptidyl-tyrosine dephosphorylation

0.76	GO:0019888	protein phosphatase regulator activity
0.38	GO:0004622	lysophospholipase activity
0.34	GO:0008080	N-acetyltransferase activity
0.33	GO:0004725	protein tyrosine phosphatase activity

0.52	GO:0016607	nuclear speck
0.51	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0042995	cell projection
0.41	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.38

EC:3.1.1.5

GO:0004622

tr|T1G7Q5|T1G7Q5_HELRO
Uncharacterized protein
Search

0.40	GO:0006357	regulation of transcription by RNA polymerase II
0.34	GO:0006468	protein phosphorylation

0.68	GO:0046983	protein dimerization activity
0.43	GO:0003677	DNA binding
0.41	GO:0001067	regulatory region nucleic acid binding
0.38	GO:0003700	DNA binding transcription factor activity
0.34	GO:0004672	protein kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.38	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|T1G7Q6|T1G7Q6_HELRO
Uncharacterized protein
Search

CLK2

0.95	Dual specificity protein kinase CLK2

0.63	GO:0006468	protein phosphorylation
0.49	GO:0032526	response to retinoic acid
0.48	GO:0045721	negative regulation of gluconeogenesis
0.48	GO:0010212	response to ionizing radiation
0.48	GO:0043484	regulation of RNA splicing
0.45	GO:0018212	peptidyl-tyrosine modification
0.41	GO:0034125	negative regulation of MyD88-dependent toll-like receptor signaling pathway
0.40	GO:2000255	negative regulation of male germ cell proliferation
0.40	GO:0030717	karyosome formation
0.40	GO:0042051	compound eye photoreceptor development

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0042802	identical protein binding
0.37	GO:0019905	syntaxin binding
0.36	GO:0016757	transferase activity, transferring glycosyl groups
0.33	GO:0003676	nucleic acid binding

0.47	GO:0016604	nuclear body
0.37	GO:0005783	endoplasmic reticulum
0.30	GO:0016021	integral component of membrane

0.36

GO:0016757

tr|T1G7Q7|T1G7Q7_HELRO
Uncharacterized protein
Search

tr|T1G7Q8|T1G7Q8_HELRO
Uncharacterized protein
Search

0.49	GO:0006338	chromatin remodeling
0.40	GO:0016567	protein ubiquitination
0.35	GO:0006261	DNA-dependent DNA replication
0.34	GO:0045944	positive regulation of transcription by RNA polymerase II
0.34	GO:0007399	nervous system development
0.34	GO:0051016	barbed-end actin filament capping
0.34	GO:0023051	regulation of signaling
0.33	GO:0071103	DNA conformation change
0.32	GO:0006333	chromatin assembly or disassembly
0.32	GO:0034728	nucleosome organization

0.53	GO:0046872	metal ion binding
0.50	GO:0003677	DNA binding
0.40	GO:0004842	ubiquitin-protein transferase activity
0.34	GO:0005515	protein binding
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0004386	helicase activity
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0042623	ATPase activity, coupled

0.58	GO:0005634	nucleus
0.37	GO:0000785	chromatin
0.36	GO:0031974	membrane-enclosed lumen
0.36	GO:1904949	ATPase complex
0.35	GO:0005700	polytene chromosome
0.34	GO:0008290	F-actin capping protein complex
0.33	GO:0033186	CAF-1 complex
0.32	GO:0045121	membrane raft
0.31	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.32	EC:2.1.1	GO:0008168
0.40	KEGG:R03876	GO:0004842

tr|T1G7Q9|T1G7Q9_HELRO
Uncharacterized protein
Search

NSFL1C

0.72	Protein tyrosine phosphatase shp1/cofactor for p97 atpase-mediated vesicle membrane fusion (Fragment)

0.62	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.60	GO:0031468	nuclear envelope reassembly
0.58	GO:0000045	autophagosome assembly
0.57	GO:0007030	Golgi organization
0.55	GO:0043666	regulation of phosphoprotein phosphatase activity
0.50	GO:0061025	membrane fusion
0.47	GO:0051028	mRNA transport
0.43	GO:0016226	iron-sulfur cluster assembly
0.39	GO:0043547	positive regulation of GTPase activity
0.38	GO:0022900	electron transport chain

0.64	GO:0043130	ubiquitin binding
0.56	GO:0019888	protein phosphatase regulator activity
0.41	GO:0051539	4 iron, 4 sulfur cluster binding
0.41	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity
0.41	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.39	GO:0005096	GTPase activator activity
0.39	GO:0009055	electron transfer activity
0.39	GO:0046872	metal ion binding
0.38	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.38	GO:0032559	adenyl ribonucleotide binding

0.56	GO:0005829	cytosol
0.54	GO:0005634	nucleus
0.51	GO:0045111	intermediate filament cytoskeleton
0.46	GO:0031974	membrane-enclosed lumen
0.42	GO:0044446	intracellular organelle part
0.41	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.41

EC:2.4.1.135

GO:0015018

tr|T1G7R0|T1G7R0_HELRO
Uncharacterized protein
Search

0.75	WW domain binding protein wBP-2

0.68	GO:0071391	cellular response to estrogen stimulus
0.67	GO:0045893	positive regulation of transcription, DNA-templated
0.66	GO:0045815	positive regulation of gene expression, epigenetic
0.64	GO:0045572	positive regulation of imaginal disc growth
0.61	GO:0035329	hippo signaling
0.60	GO:0006366	transcription by RNA polymerase II
0.56	GO:0006357	regulation of transcription by RNA polymerase II
0.53	GO:0071442	positive regulation of histone H3-K14 acetylation
0.53	GO:0050847	progesterone receptor signaling pathway
0.52	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway

0.67	GO:0001105	RNA polymerase II transcription coactivator activity
0.57	GO:0032266	phosphatidylinositol-3-phosphate binding
0.56	GO:0043130	ubiquitin binding
0.51	GO:0030331	estrogen receptor binding
0.51	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding
0.50	GO:0031490	chromatin DNA binding
0.37	GO:0008061	chitin binding
0.37	GO:0050699	WW domain binding
0.35	GO:0003899	DNA-directed 5'-3' RNA polymerase activity

0.59	GO:0000790	nuclear chromatin
0.43	GO:0005737	cytoplasm
0.36	GO:0005576	extracellular region
0.35	GO:0009530	primary cell wall
0.34	GO:0005856	cytoskeleton

0.35

GO:0003899

tr|T1G7R1|T1G7R1_HELRO
Uncharacterized protein
Search

0.54	52 kDa repressor of the inhibitor of the protein kinase

0.56

GO:0016310

phosphorylation

0.68	GO:0046983	protein dimerization activity
0.59	GO:0016301	kinase activity

tr|T1G7R2|T1G7R2_HELRO
Uncharacterized protein
Search

FARSA

0.44	Phenylalanyl-tRNA synthetase alpha subunit

0.77	GO:0006432	phenylalanyl-tRNA aminoacylation
0.54	GO:0051290	protein heterotetramerization
0.37	GO:0106074	aminoacyl-tRNA metabolism involved in translational fidelity

0.76	GO:0004826	phenylalanine-tRNA ligase activity
0.69	GO:0000049	tRNA binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0002161	aminoacyl-tRNA editing activity
0.33	GO:0005515	protein binding

0.58	GO:0009328	phenylalanine-tRNA ligase complex
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.76

EC:6.1.1.20

GO:0004826

tr|T1G7R3|T1G7R3_HELRO
UDP-glucose 6-dehydrogenase
Search

0.45	UDP-glucose 6-dehydrogenase

0.53	GO:0055114	oxidation-reduction process
0.51	GO:0007369	gastrulation
0.47	GO:0006024	glycosaminoglycan biosynthetic process
0.44	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process
0.44	GO:0007427	epithelial cell migration, open tracheal system
0.44	GO:0008078	mesodermal cell migration
0.44	GO:0007367	segment polarity determination
0.44	GO:0048729	tissue morphogenesis
0.43	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process
0.43	GO:0030204	chondroitin sulfate metabolic process

0.78	GO:0003979	UDP-glucose 6-dehydrogenase activity
0.68	GO:0051287	NAD binding
0.37	GO:0042802	identical protein binding
0.33	GO:0009055	electron transfer activity

0.44	GO:0005634	nucleus
0.44	GO:0005829	cytosol
0.43	GO:0043233	organelle lumen
0.39	GO:0044446	intracellular organelle part
0.35	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.78	EC:1.1.1.22	GO:0003979
0.78	KEGG:R00286	GO:0003979

tr|T1G7R4|T1G7R4_HELRO
Uncharacterized protein
Search

0.28	Phospholipid-transporting ATPase

0.80	GO:0045332	phospholipid translocation
0.40	GO:2001141	regulation of RNA biosynthetic process
0.40	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.40	GO:0010468	regulation of gene expression
0.34	GO:0048194	Golgi vesicle budding
0.33	GO:0022900	electron transport chain
0.32	GO:0016310	phosphorylation

0.80	GO:0004012	phospholipid-translocating ATPase activity
0.64	GO:0000287	magnesium ion binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0017056	structural constituent of nuclear pore
0.43	GO:0043565	sequence-specific DNA binding
0.34	GO:0008121	ubiquinol-cytochrome-c reductase activity
0.33	GO:0016301	kinase activity

0.47	GO:0005643	nuclear pore
0.34	GO:0005802	trans-Golgi network
0.33	GO:0000139	Golgi membrane
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.80

EC:3.6.3.1

GO:0004012

tr|T1G7R5|T1G7R5_HELRO
Uncharacterized protein
Search

tr|T1G7R6|T1G7R6_HELRO
Uncharacterized protein
Search

BRE4

0.57	N-acetyllactosaminide 3-alpha-galactosyltransferase

0.60	GO:0005975	carbohydrate metabolic process
0.39	GO:0045747	positive regulation of Notch signaling pathway
0.38	GO:0043413	macromolecule glycosylation
0.38	GO:0009101	glycoprotein biosynthetic process
0.37	GO:0009636	response to toxic substance
0.35	GO:0006464	cellular protein modification process

0.65	GO:0016757	transferase activity, transferring glycosyl groups
0.33	GO:0046872	metal ion binding
0.32	GO:0003723	RNA binding

0.30

GO:0044425

membrane part

0.65

GO:0016757

tr|T1G7R7|T1G7R7_HELRO
Ribosomal protein L15
Search

RPL15

0.64	Ribosomal protein L15

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.36	GO:0045471	response to ethanol
0.35	GO:0055085	transmembrane transport
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.33	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.33	GO:0019083	viral transcription
0.33	GO:0016072	rRNA metabolic process

0.64	GO:0003735	structural constituent of ribosome
0.44	GO:0045296	cadherin binding
0.38	GO:0003723	RNA binding
0.32	GO:0016787	hydrolase activity

0.61	GO:0005840	ribosome
0.41	GO:0044445	cytosolic part
0.39	GO:0005634	nucleus
0.38	GO:0044446	intracellular organelle part
0.36	GO:0031672	A band
0.35	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016787

tr|T1G7R8|T1G7R8_HELRO
Uncharacterized protein
Search

tr|T1G7R9|T1G7R9_HELRO
Uncharacterized protein
Search

0.47	Molting carboxypeptidase A

0.61	GO:0006508	proteolysis
0.36	GO:0071555	cell wall organization
0.33	GO:0007186	G-protein coupled receptor signaling pathway

0.78	GO:0004181	metallocarboxypeptidase activity
0.63	GO:0008270	zinc ion binding
0.33	GO:0004930	G-protein coupled receptor activity

0.39	GO:0005615	extracellular space
0.39	GO:0046658	anchored component of plasma membrane
0.37	GO:0005773	vacuole
0.30	GO:0016021	integral component of membrane

0.78

EC:3.4.17

GO:0004181

tr|T1G7S0|T1G7S0_HELRO
Uncharacterized protein
Search

tr|T1G7S1|T1G7S1_HELRO
Uncharacterized protein
Search

0.51	Mitochondrial glutamate carrier (Fragment)

0.49	GO:0055085	transmembrane transport
0.37	GO:0015740	C4-dicarboxylate transport
0.36	GO:0006862	nucleotide transport
0.36	GO:0015893	drug transport
0.35	GO:0015800	acidic amino acid transport
0.35	GO:0015807	L-amino acid transport
0.35	GO:0051881	regulation of mitochondrial membrane potential
0.35	GO:0006836	neurotransmitter transport
0.35	GO:0015709	thiosulfate transport
0.35	GO:0000002	mitochondrial genome maintenance

0.37	GO:0015556	C4-dicarboxylate transmembrane transporter activity
0.37	GO:0015215	nucleotide transmembrane transporter activity
0.36	GO:0015292	uniporter activity
0.36	GO:0015238	drug transmembrane transporter activity
0.36	GO:0015297	antiporter activity
0.35	GO:0015172	acidic amino acid transmembrane transporter activity
0.35	GO:0015179	L-amino acid transmembrane transporter activity
0.35	GO:0005326	neurotransmitter transporter activity
0.35	GO:0015117	thiosulfate transmembrane transporter activity
0.34	GO:0015116	sulfate transmembrane transporter activity

0.36	GO:1990816	vacuole-mitochondrion membrane contact site
0.35	GO:0005739	mitochondrion
0.34	GO:0005779	integral component of peroxisomal membrane
0.33	GO:0019866	organelle inner membrane

tr|T1G7S2|T1G7S2_HELRO
Uncharacterized protein
Search

GTF2E1

0.62	general transcription factor IIE subunit 1

0.79	GO:0006367	transcription initiation from RNA polymerase II promoter
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.40	GO:1902680	positive regulation of RNA biosynthetic process
0.39	GO:0006413	translational initiation
0.35	GO:0018108	peptidyl-tyrosine phosphorylation
0.34	GO:0042795	snRNA transcription by RNA polymerase II
0.34	GO:0006368	transcription elongation from RNA polymerase II promoter
0.33	GO:0016192	vesicle-mediated transport

0.65	GO:0043565	sequence-specific DNA binding
0.39	GO:0003743	translation initiation factor activity
0.35	GO:0004713	protein tyrosine kinase activity
0.34	GO:0046872	metal ion binding
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005515	protein binding

0.52	GO:0097550	transcriptional preinitiation complex
0.50	GO:0090575	RNA polymerase II transcription factor complex
0.50	GO:0016591	DNA-directed RNA polymerase II, holoenzyme
0.44	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.35

GO:0004713

tr|T1G7S3|T1G7S3_HELRO
Uncharacterized protein
Search

0.51	Zinc finger MYM-type protein 1

0.34	GO:0046080	dUTP metabolic process
0.34	GO:0006357	regulation of transcription by RNA polymerase II
0.34	GO:0007275	multicellular organism development
0.34	GO:0016310	phosphorylation

0.68	GO:0046983	protein dimerization activity
0.35	GO:0019901	protein kinase binding
0.34	GO:0004170	dUTP diphosphatase activity
0.34	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.34	GO:0016301	kinase activity
0.32	GO:0003677	DNA binding

0.34	GO:0005654	nucleoplasm
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.34	EC:3.6.1.23	GO:0004170
0.34	KEGG:R02100	GO:0004170

tr|T1G7S4|T1G7S4_HELRO
Uncharacterized protein
Search

0.41	Copper-transporting ATPase 1

0.68	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.65	GO:0030001	metal ion transport
0.40	GO:0051208	sequestering of calcium ion
0.38	GO:0046688	response to copper ion
0.37	GO:0098662	inorganic cation transmembrane transport
0.37	GO:0046916	cellular transition metal ion homeostasis
0.36	GO:0055069	zinc ion homeostasis
0.35	GO:0055070	copper ion homeostasis
0.35	GO:0055072	iron ion homeostasis
0.34	GO:0072511	divalent inorganic cation transport

0.70	GO:0005507	copper ion binding
0.69	GO:0019829	cation-transporting ATPase activity
0.53	GO:1901265	nucleoside phosphate binding
0.51	GO:0036094	small molecule binding
0.40	GO:0005375	copper ion transmembrane transporter activity
0.38	GO:0015662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
0.35	GO:0015085	calcium ion transmembrane transporter activity
0.34	GO:0097367	carbohydrate derivative binding
0.34	GO:0008144	drug binding
0.34	GO:0043168	anion binding

0.39	GO:0032588	trans-Golgi network membrane
0.38	GO:0016323	basolateral plasma membrane
0.38	GO:0005770	late endosome
0.38	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0012510	trans-Golgi network transport vesicle membrane
0.32	GO:0032580	Golgi cisterna membrane
0.30	GO:0016021	integral component of membrane

0.32

GO:0008417

tr|T1G7S5|T1G7S5_HELRO
Uncharacterized protein
Search

0.96	Heterogeneous nuclear ribonucleoprotein A2 homolog 1

0.49	GO:0001745	compound eye morphogenesis
0.49	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.46	GO:0036099	female germ-line stem cell population maintenance
0.46	GO:0003006	developmental process involved in reproduction
0.46	GO:0033119	negative regulation of RNA splicing
0.44	GO:0007292	female gamete generation
0.43	GO:0022412	cellular process involved in reproduction in multicellular organism
0.43	GO:0045727	positive regulation of translation
0.42	GO:0048468	cell development
0.41	GO:0061458	reproductive system development

0.59	GO:0003723	RNA binding
0.42	GO:0043565	sequence-specific DNA binding
0.33	GO:0003777	microtubule motor activity
0.33	GO:0051082	unfolded protein binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.54	GO:0019013	viral nucleocapsid
0.51	GO:0030529	intracellular ribonucleoprotein complex
0.50	GO:0005703	polytene chromosome puff
0.44	GO:0035062	omega speckle
0.42	GO:0000792	heterochromatin
0.34	GO:0030286	dynein complex
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1G7S6|T1G7S6_HELRO
Uncharacterized protein
Search

0.74	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway
0.65	GO:0046541	saliva secretion
0.55	GO:0045987	positive regulation of smooth muscle contraction
0.51	GO:0050890	cognition
0.49	GO:0040012	regulation of locomotion
0.45	GO:0009612	response to mechanical stimulus
0.44	GO:0006954	inflammatory response
0.42	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.42	GO:0032496	response to lipopolysaccharide
0.41	GO:0007271	synaptic transmission, cholinergic

0.75	GO:0016907	G-protein coupled acetylcholine receptor activity
0.48	GO:0004947	bradykinin receptor activity
0.43	GO:0042277	peptide binding
0.38	GO:0001594	trace-amine receptor activity
0.36	GO:0004950	chemokine receptor activity
0.36	GO:0099589	serotonin receptor activity

0.65	GO:0045211	postsynaptic membrane
0.62	GO:0030054	cell junction
0.60	GO:0005887	integral component of plasma membrane

tr|T1G7S7|T1G7S7_HELRO
Uncharacterized protein
Search

0.70	Leucine-rich repeat and calponin homology domain-containing protein 2 (Fragment)

0.49	GO:0007165	signal transduction
0.47	GO:0031032	actomyosin structure organization

0.46	GO:0005516	calmodulin binding
0.44	GO:0003779	actin binding

0.46	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

tr|T1G7S8|T1G7S8_HELRO
Uncharacterized protein
Search

tr|T1G7S9|T1G7S9_HELRO
Uncharacterized protein
Search

0.35	GO:0070647	protein modification by small protein conjugation or removal
0.34	GO:0042073	intraciliary transport
0.34	GO:0060271	cilium assembly
0.33	GO:0006351	transcription, DNA-templated
0.33	GO:0006508	proteolysis
0.33	GO:0006313	transposition, DNA-mediated
0.33	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:0015074	DNA integration
0.33	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.33	GO:0016192	vesicle-mediated transport

0.35	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.34	GO:0004842	ubiquitin-protein transferase activity
0.34	GO:0015631	tubulin binding
0.34	GO:0031683	G-protein beta/gamma-subunit complex binding
0.33	GO:0003677	DNA binding
0.33	GO:0000062	fatty-acyl-CoA binding
0.33	GO:0008270	zinc ion binding
0.33	GO:0003700	DNA binding transcription factor activity
0.33	GO:0003924	GTPase activity
0.33	GO:0036094	small molecule binding

0.35	GO:0030992	intraciliary transport particle B
0.34	GO:0031514	motile cilium
0.34	GO:0030008	TRAPP complex
0.33	GO:0043231	intracellular membrane-bounded organelle
0.32	GO:0044444	cytoplasmic part
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.33	EC:2.7	GO:0016772
0.34	KEGG:R03876	GO:0004842

tr|T1G7T0|T1G7T0_HELRO
Uncharacterized protein
Search

0.38	DEAD box ATP-dependent RNA helicase

0.42	GO:0010501	RNA secondary structure unwinding
0.34	GO:0031047	gene silencing by RNA
0.34	GO:0006955	immune response
0.33	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.33	GO:0006396	RNA processing

0.66	GO:0004386	helicase activity
0.56	GO:0003723	RNA binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0008186	RNA-dependent ATPase activity
0.38	GO:0140098	catalytic activity, acting on RNA
0.36	GO:0008270	zinc ion binding
0.33	GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
0.32	GO:0016740	transferase activity

0.40	GO:0005730	nucleolus
0.35	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:3.1.30

GO:0016893

tr|T1G7T1|T1G7T1_HELRO
Uncharacterized protein
Search

ATOH8

0.87	Putative bhlh factor math6 atoh8 protein bhlh transcription factor (Fragment)

0.72	GO:0030154	cell differentiation
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.49	GO:0035239	tube morphogenesis
0.48	GO:0045603	positive regulation of endothelial cell differentiation
0.47	GO:0001937	negative regulation of endothelial cell proliferation
0.47	GO:0051450	myoblast proliferation
0.47	GO:0060395	SMAD protein signal transduction
0.47	GO:0010595	positive regulation of endothelial cell migration

0.68	GO:0046983	protein dimerization activity
0.61	GO:0003700	DNA binding transcription factor activity
0.48	GO:0070888	E-box binding
0.45	GO:0033613	activating transcription factor binding
0.34	GO:0005179	hormone activity

0.42	GO:0005654	nucleoplasm
0.35	GO:0005737	cytoplasm
0.33	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

tr|T1G7T2|T1G7T2_HELRO
Uncharacterized protein
Search

0.78	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.60	GO:0023014	signal transduction by protein phosphorylation
0.57	GO:0035556	intracellular signal transduction
0.54	GO:0010750	positive regulation of nitric oxide mediated signal transduction
0.52	GO:1900020	positive regulation of protein kinase C activity
0.52	GO:0031659	positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle
0.52	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA
0.52	GO:0070141	response to UV-A
0.52	GO:0035413	positive regulation of catenin import into nucleus

0.80	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.78	GO:0004716	signal transducer, downstream of receptor, with protein tyrosine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0030235	nitric-oxide synthase regulator activity
0.49	GO:0019903	protein phosphatase binding
0.48	GO:0045296	cadherin binding
0.48	GO:0031625	ubiquitin protein ligase binding

0.53	GO:0097489	multivesicular body, internal vesicle lumen
0.50	GO:0031901	early endosome membrane
0.49	GO:0016323	basolateral plasma membrane
0.48	GO:0098857	membrane microdomain
0.47	GO:0043235	receptor complex
0.46	GO:0009986	cell surface
0.43	GO:0030139	endocytic vesicle
0.43	GO:0048471	perinuclear region of cytoplasm
0.42	GO:0005634	nucleus
0.41	GO:0043234	protein complex

0.80	EC:2.7.10.1	GO:0004714
0.36	KEGG:R04545	GO:0046934

tr|T1G7T3|T1G7T3_HELRO
Uncharacterized protein
Search

tr|T1G7T4|T1G7T4_HELRO
Protein Wnt
Search

0.77	GO:0016055	Wnt signaling pathway
0.70	GO:0007275	multicellular organism development
0.45	GO:0045165	cell fate commitment
0.42	GO:0009653	anatomical structure morphogenesis
0.42	GO:0051239	regulation of multicellular organismal process
0.42	GO:0033079	immature T cell proliferation
0.42	GO:0031945	positive regulation of glucocorticoid metabolic process
0.42	GO:0030334	regulation of cell migration
0.42	GO:0045597	positive regulation of cell differentiation
0.42	GO:2000225	negative regulation of testosterone biosynthetic process

0.73	GO:0005102	receptor binding
0.39	GO:0003714	transcription corepressor activity
0.35	GO:1990782	protein tyrosine kinase binding
0.33	GO:0030545	receptor regulator activity
0.32	GO:0004871	signal transducer activity

0.75	GO:0005578	proteinaceous extracellular matrix
0.42	GO:0005615	extracellular space
0.40	GO:0009986	cell surface
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|T1G7T5|T1G7T5_HELRO
Uncharacterized protein
Search

tr|T1G7T7|T1G7T7_HELRO
Uncharacterized protein
Search

NT5E

0.39	Ecto-5'-nucleotidase

0.75	GO:0009166	nucleotide catabolic process
0.49	GO:0046086	adenosine biosynthetic process
0.48	GO:0007159	leukocyte cell-cell adhesion
0.48	GO:0009169	purine ribonucleoside monophosphate catabolic process
0.47	GO:0050728	negative regulation of inflammatory response
0.45	GO:0016311	dephosphorylation
0.44	GO:0072523	purine-containing compound catabolic process
0.44	GO:0046033	AMP metabolic process
0.43	GO:0042737	drug catabolic process
0.43	GO:1901136	carbohydrate derivative catabolic process

0.61	GO:0016788	hydrolase activity, acting on ester bonds
0.54	GO:0046872	metal ion binding
0.53	GO:1901265	nucleoside phosphate binding
0.51	GO:0036094	small molecule binding

0.42	GO:0005654	nucleoplasm
0.42	GO:0005829	cytosol
0.39	GO:0031225	anchored component of membrane
0.39	GO:0005886	plasma membrane
0.35	GO:0070062	extracellular exosome
0.35	GO:0009986	cell surface
0.34	GO:0044456	synapse part
0.30	GO:0016021	integral component of membrane

0.61

EC:3.1

GO:0016788

tr|T1G7T8|T1G7T8_HELRO
Uncharacterized protein
Search

ISL2

0.91	Insulin protein enhancer protein ISL-2

0.59	GO:0048665	neuron fate specification
0.59	GO:0021524	visceral motor neuron differentiation
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0007409	axonogenesis
0.55	GO:0097485	neuron projection guidance
0.54	GO:0045665	negative regulation of neuron differentiation
0.46	GO:0031017	exocrine pancreas development
0.45	GO:1990138	neuron projection extension

0.65	GO:0043565	sequence-specific DNA binding
0.53	GO:0046872	metal ion binding
0.36	GO:0001133	RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding
0.35	GO:0001102	RNA polymerase II activating transcription factor binding
0.35	GO:0035326	enhancer binding
0.35	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.35	GO:0001012	RNA polymerase II regulatory region DNA binding
0.34	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|T1G7T9|T1G7T9_HELRO
Uncharacterized protein
Search

0.69	GO:0007186	G-protein coupled receptor signaling pathway
0.60	GO:0007166	cell surface receptor signaling pathway

0.70

GO:0004930

G-protein coupled receptor activity

0.30

GO:0044425

membrane part

tr|T1G7U0|T1G7U0_HELRO
Uncharacterized protein
Search

tr|T1G7U1|T1G7U1_HELRO
Uncharacterized protein
Search

0.44

Calponin

0.72	GO:0030036	actin cytoskeleton organization
0.70	GO:0001300	chronological cell aging
0.61	GO:0097435	supramolecular fiber organization
0.45	GO:0000281	mitotic cytokinesis

0.72	GO:0003779	actin binding
0.66	GO:0030674	protein binding, bridging
0.62	GO:0032403	protein complex binding
0.62	GO:0005516	calmodulin binding

0.68	GO:0030479	actin cortical patch
0.30	GO:0044425	membrane part

tr|T1G7U2|T1G7U2_HELRO
Uncharacterized protein
Search

0.10	Tyrosine-protein phosphatase 1

0.60	GO:0030866	cortical actin cytoskeleton organization
0.50	GO:1904778	positive regulation of protein localization to cell cortex
0.41	GO:0031032	actomyosin structure organization
0.35	GO:0035335	peptidyl-tyrosine dephosphorylation
0.34	GO:0007016	cytoskeletal anchoring at plasma membrane
0.33	GO:0001558	regulation of cell growth
0.33	GO:0051301	cell division
0.33	GO:0007049	cell cycle
0.33	GO:0008360	regulation of cell shape

0.66	GO:0008092	cytoskeletal protein binding
0.53	GO:0005198	structural molecule activity
0.49	GO:0042731	PH domain binding
0.35	GO:0004725	protein tyrosine phosphatase activity

0.69	GO:0005856	cytoskeleton
0.47	GO:0099738	cell cortex region
0.46	GO:0008180	COP9 signalosome
0.45	GO:0030054	cell junction
0.42	GO:0005654	nucleoplasm
0.39	GO:0005886	plasma membrane
0.37	GO:0070062	extracellular exosome
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.35

GO:0004725

tr|T1G7U3|T1G7U3_HELRO
Uncharacterized protein
Search

tr|T1G7U4|T1G7U4_HELRO
Uncharacterized protein
Search

0.49	Zinc finger MYM-type protein 1

0.68

GO:0046983

protein dimerization activity

tr|T1G7U5|T1G7U5_HELRO
Uncharacterized protein
Search

0.28	Histidine protein methyltransferase 1-like protein (Fragment)

0.63	GO:0032259	methylation
0.42	GO:0045903	positive regulation of translational fidelity
0.40	GO:0000027	ribosomal large subunit assembly
0.39	GO:0008213	protein alkylation
0.39	GO:0018202	peptidyl-histidine modification

0.63

GO:0008168

methyltransferase activity

0.63

GO:0008168

tr|T1G7U6|T1G7U6_HELRO
Uncharacterized protein
Search

HERC1

0.48	HECT and RLD domain containing E3 ubiquitin protein ligase family member 1

0.72	GO:0016567	protein ubiquitination
0.69	GO:0021702	cerebellar Purkinje cell differentiation
0.67	GO:0050885	neuromuscular process controlling balance
0.61	GO:0031175	neuron projection development
0.59	GO:0010507	negative regulation of autophagy

0.73	GO:0004842	ubiquitin-protein transferase activity
0.46	GO:0016874	ligase activity

0.46	EC:6	GO:0016874
0.73	KEGG:R03876	GO:0004842

tr|T1G7U7|T1G7U7_HELRO
Uncharacterized protein
Search

0.11	probable E3 ubiquitin-protein ligase HERC1

0.68	GO:0016567	protein ubiquitination
0.37	GO:0021702	cerebellar Purkinje cell differentiation
0.37	GO:0050885	neuromuscular process controlling balance
0.36	GO:0031175	neuron projection development
0.35	GO:0010507	negative regulation of autophagy
0.34	GO:0065009	regulation of molecular function
0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression

0.69	GO:0004842	ubiquitin-protein transferase activity
0.62	GO:0016874	ligase activity
0.36	GO:0005086	ARF guanyl-nucleotide exchange factor activity

0.35	GO:0005794	Golgi apparatus
0.35	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.62	EC:6	GO:0016874
0.69	KEGG:R03876	GO:0004842

tr|T1G7U8|T1G7U8_HELRO
Uncharacterized protein
Search

0.45	Peptidoglycan-binding domain 1 protein, putative

0.30

GO:0044425

membrane part

tr|T1G7U9|T1G7U9_HELRO
Uncharacterized protein
Search

tr|T1G7V0|T1G7V0_HELRO
Uncharacterized protein
Search

tr|T1G7V1|T1G7V1_HELRO
Uncharacterized protein
Search

ACSBG2

0.75	Acyl-CoA synthetase bubblegum family member 2

0.53

GO:0001676

long-chain fatty acid metabolic process

0.54	GO:0047617	acyl-CoA hydrolase activity
0.54	GO:0004467	long-chain fatty acid-CoA ligase activity

0.48	GO:0005829	cytosol
0.45	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.54

EC:3.1.2 EC:3.1.2.20

GO:0047617

tr|T1G7V2|T1G7V2_HELRO
Uncharacterized protein
Search

GAR-2

0.63	G-protein-linked Acetylcholine Receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.67	GO:0095500	acetylcholine receptor signaling pathway
0.51	GO:0046541	saliva secretion
0.51	GO:0045987	positive regulation of smooth muscle contraction
0.41	GO:0007271	synaptic transmission, cholinergic
0.35	GO:0006939	smooth muscle contraction
0.35	GO:0032223	negative regulation of synaptic transmission, cholinergic
0.34	GO:0003056	regulation of vascular smooth muscle contraction
0.34	GO:0018108	peptidyl-tyrosine phosphorylation

0.72	GO:0004930	G-protein coupled receptor activity
0.67	GO:0015464	acetylcholine receptor activity
0.34	GO:0004715	non-membrane spanning protein tyrosine kinase activity

0.53	GO:0005887	integral component of plasma membrane
0.47	GO:0045211	postsynaptic membrane
0.46	GO:0030054	cell junction
0.34	GO:0030424	axon

0.34

GO:0004715

tr|T1G7V3|T1G7V3_HELRO
Uncharacterized protein
Search

0.86	G-protein-linked acetylcholine receptor protein 2

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.64	GO:0095500	acetylcholine receptor signaling pathway
0.40	GO:0007271	synaptic transmission, cholinergic
0.35	GO:0032223	negative regulation of synaptic transmission, cholinergic
0.35	GO:0001525	angiogenesis
0.34	GO:0046541	saliva secretion
0.34	GO:0018108	peptidyl-tyrosine phosphorylation
0.34	GO:0050890	cognition
0.33	GO:0040012	regulation of locomotion

0.72	GO:0004930	G-protein coupled receptor activity
0.64	GO:0015464	acetylcholine receptor activity
0.34	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.33	GO:0001653	peptide receptor activity

0.52	GO:0005887	integral component of plasma membrane
0.34	GO:0030424	axon
0.33	GO:0030139	endocytic vesicle
0.33	GO:0009986	cell surface

0.34

GO:0004715

tr|T1G7V4|T1G7V4_HELRO
Uncharacterized protein
Search

0.73	GO:0043401	steroid hormone mediated signaling pathway
0.69	GO:0030522	intracellular receptor signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.41	GO:0007553	regulation of ecdysteroid metabolic process
0.40	GO:0018990	ecdysis, chitin-based cuticle
0.40	GO:0035075	response to ecdysone
0.39	GO:0019730	antimicrobial humoral response

0.75	GO:0003707	steroid hormone receptor activity
0.74	GO:0004887	thyroid hormone receptor activity
0.65	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.36	GO:0020037	heme binding
0.35	GO:0001012	RNA polymerase II regulatory region DNA binding
0.35	GO:0005496	steroid binding
0.35	GO:0003690	double-stranded DNA binding
0.34	GO:0008061	chitin binding
0.33	GO:0004386	helicase activity

0.61	GO:0005634	nucleus
0.33	GO:0005576	extracellular region
0.30	GO:0016020	membrane

tr|T1G7V5|T1G7V5_HELRO
Uncharacterized protein
Search

0.43	Calcium/calmodulin-dependent protein kinase I, isoform H

0.63	GO:0006468	protein phosphorylation
0.40	GO:0032793	positive regulation of CREB transcription factor activity
0.39	GO:0018210	peptidyl-threonine modification
0.39	GO:0018209	peptidyl-serine modification
0.39	GO:0045664	regulation of neuron differentiation
0.38	GO:0060267	positive regulation of respiratory burst
0.38	GO:0040040	thermosensory behavior
0.37	GO:0090023	positive regulation of neutrophil chemotaxis
0.37	GO:0050766	positive regulation of phagocytosis
0.37	GO:0050773	regulation of dendrite development

0.65	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0005516	calmodulin binding
0.35	GO:0003707	steroid hormone receptor activity
0.35	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.35	GO:0031418	L-ascorbic acid binding
0.34	GO:0005509	calcium ion binding
0.33	GO:0043565	sequence-specific DNA binding

0.36	GO:0005829	cytosol
0.36	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.65

GO:0004674

tr|T1G7V6|T1G7V6_HELRO
Uncharacterized protein
Search

0.51	Syntaxin binding protein 5 like

0.69	GO:0016192	vesicle-mediated transport
0.50	GO:0017157	regulation of exocytosis
0.49	GO:0050708	regulation of protein secretion
0.47	GO:0043547	positive regulation of GTPase activity
0.38	GO:0090278	negative regulation of peptide hormone secretion
0.37	GO:0002793	positive regulation of peptide secretion
0.37	GO:0051224	negative regulation of protein transport
0.37	GO:1903532	positive regulation of secretion by cell
0.37	GO:0042593	glucose homeostasis
0.37	GO:0051222	positive regulation of protein transport

0.51	GO:0019905	syntaxin binding
0.48	GO:0017137	Rab GTPase binding
0.47	GO:0005096	GTPase activator activity

0.50	GO:0005829	cytosol
0.40	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1G7V7|T1G7V7_HELRO
Uncharacterized protein
Search

KDM1A

0.85	Lysine specific histone demethylase

0.84	GO:0034720	histone H3-K4 demethylation
0.57	GO:0032259	methylation
0.55	GO:2001141	regulation of RNA biosynthetic process
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.54	GO:0033184	positive regulation of histone ubiquitination
0.54	GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
0.53	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator
0.53	GO:0033169	histone H3-K9 demethylation
0.53	GO:0071480	cellular response to gamma radiation

0.63	GO:0050660	flavin adenine dinucleotide binding
0.57	GO:0008168	methyltransferase activity
0.55	GO:0061752	telomeric repeat-containing RNA binding
0.54	GO:0043426	MRF binding
0.54	GO:0034648	histone demethylase activity (H3-dimethyl-K4 specific)
0.53	GO:0003677	DNA binding
0.53	GO:0032454	histone demethylase activity (H3-K9 specific)
0.53	GO:0050681	androgen receptor binding
0.52	GO:0016491	oxidoreductase activity
0.51	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity

0.59	GO:0005634	nucleus
0.49	GO:0000781	chromosome, telomeric region
0.47	GO:1990391	DNA repair complex
0.46	GO:0000785	chromatin
0.44	GO:0070013	intracellular organelle lumen
0.42	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.57

GO:0008168

tr|T1G7V8|T1G7V8_HELRO
Uncharacterized protein
Search

0.57	Poly polymerase gamma

0.80	GO:0043631	RNA polyadenylation
0.76	GO:0031123	RNA 3'-end processing
0.36	GO:0006397	mRNA processing

0.78	GO:0004652	polynucleotide adenylyltransferase activity
0.59	GO:0003723	RNA binding
0.51	GO:0030554	adenyl nucleotide binding
0.50	GO:0097367	carbohydrate derivative binding
0.50	GO:0008144	drug binding
0.50	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0046872	metal ion binding

0.61	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.78

EC:2.7.7.19

GO:0004652

tr|T1G7V9|T1G7V9_HELRO
Uncharacterized protein
Search

CCNH

0.81	CDK activating kinase

0.74	GO:0045859	regulation of protein kinase activity
0.56	GO:0006351	transcription, DNA-templated
0.43	GO:1901409	positive regulation of phosphorylation of RNA polymerase II C-terminal domain
0.42	GO:0045944	positive regulation of transcription by RNA polymerase II
0.41	GO:0051726	regulation of cell cycle
0.41	GO:0033674	positive regulation of kinase activity
0.39	GO:0010672	regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle
0.39	GO:0051039	positive regulation of transcription involved in meiotic cell cycle
0.38	GO:0000411	positive regulation of transcription by galactose
0.37	GO:0000122	negative regulation of transcription by RNA polymerase II

0.81	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity
0.39	GO:0004693	cyclin-dependent protein serine/threonine kinase activity
0.39	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity
0.38	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding
0.34	GO:0000990	transcription factor activity, core RNA polymerase binding
0.34	GO:0005179	hormone activity
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0008144	drug binding

0.81	GO:0070985	TFIIK complex
0.42	GO:0016592	mediator complex
0.42	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.33	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.81

GO:0016538

tr|T1G7W0|T1G7W0_HELRO
Uncharacterized protein
Search

tr|T1G7W1|T1G7W1_HELRO
Uncharacterized protein
Search

tr|T1G7W2|T1G7W2_HELRO
Uncharacterized protein
Search

tr|T1G7W3|T1G7W3_HELRO
Uncharacterized protein
Search

0.81	Nuclear division rft1 protein

0.74	GO:0006869	lipid transport
0.45	GO:0097035	regulation of membrane lipid distribution
0.44	GO:0051603	proteolysis involved in cellular protein catabolic process
0.43	GO:1901264	carbohydrate derivative transport
0.35	GO:0008643	carbohydrate transport

0.77	GO:0005319	lipid transporter activity
0.46	GO:0070003	threonine-type peptidase activity
0.42	GO:0004175	endopeptidase activity
0.33	GO:0046983	protein dimerization activity
0.31	GO:0003677	DNA binding

0.45	GO:0005839	proteasome core complex
0.43	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

tr|T1G7W4|T1G7W4_HELRO
Uncharacterized protein
Search

tr|T1G7W5|T1G7W5_HELRO
Uncharacterized protein
Search

KRAS

0.85	-Ha-ras Harvey rat sarcoma viral oncogene homolog b

0.61	GO:0007165	signal transduction
0.52	GO:0008284	positive regulation of cell proliferation
0.49	GO:0001936	regulation of endothelial cell proliferation
0.44	GO:0038002	endocrine signaling
0.44	GO:0021897	forebrain astrocyte development
0.44	GO:0048169	regulation of long-term neuronal synaptic plasticity
0.44	GO:0035022	positive regulation of Rac protein signal transduction
0.43	GO:0043524	negative regulation of neuron apoptotic process
0.43	GO:0060441	epithelial tube branching involved in lung morphogenesis
0.43	GO:0048873	homeostasis of number of cells within a tissue

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.48	GO:0032403	protein complex binding
0.36	GO:0003876	AMP deaminase activity
0.36	GO:0019003	GDP binding
0.36	GO:0008022	protein C-terminus binding
0.32	GO:0003677	DNA binding
0.32	GO:0046872	metal ion binding

0.46	GO:0005794	Golgi apparatus
0.42	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.39	GO:0098588	bounding membrane of organelle
0.38	GO:0031984	organelle subcompartment
0.36	GO:0070062	extracellular exosome
0.35	GO:0070820	tertiary granule
0.34	GO:0030659	cytoplasmic vesicle membrane
0.33	GO:0098805	whole membrane
0.33	GO:0005829	cytosol

0.36

EC:3.5.4.6

GO:0003876

tr|T1G7W6|T1G7W6_HELRO
Uncharacterized protein
Search

0.76	Casein kinase II subunit alpha

0.63	GO:0006468	protein phosphorylation
0.39	GO:0043666	regulation of phosphoprotein phosphatase activity
0.35	GO:0034477	U6 snRNA 3'-end processing
0.34	GO:0030307	positive regulation of cell growth
0.34	GO:0048511	rhythmic process
0.34	GO:0045732	positive regulation of protein catabolic process
0.34	GO:0008284	positive regulation of cell proliferation
0.34	GO:0016055	Wnt signaling pathway
0.33	GO:0090305	nucleic acid phosphodiester bond hydrolysis

0.68	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0008013	beta-catenin binding
0.39	GO:0019888	protein phosphatase regulator activity
0.33	GO:0004518	nuclease activity

0.34	GO:0031519	PcG protein complex
0.33	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

0.68

GO:0004674

tr|T1G7W7|T1G7W7_HELRO
Uncharacterized protein
Search

UBE2Q1

0.65	Ubiquitin--protein ligase

0.69	GO:0070459	prolactin secretion
0.65	GO:0007617	mating behavior
0.63	GO:0009566	fertilization
0.61	GO:0016567	protein ubiquitination
0.60	GO:0061458	reproductive system development
0.56	GO:0001967	suckling behavior
0.55	GO:0007566	embryo implantation
0.41	GO:0071586	CAAX-box protein processing
0.41	GO:0040011	locomotion

0.66	GO:0061631	ubiquitin conjugating enzyme activity
0.49	GO:0016874	ligase activity
0.39	GO:0004222	metalloendopeptidase activity

0.45	GO:0043025	neuronal cell body
0.41	GO:0005829	cytosol
0.39	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.49

GO:0016874

tr|T1G7W8|T1G7W8_HELRO
Uncharacterized protein
Search

0.67	GO:0007275	multicellular organism development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.46	GO:0061448	connective tissue development
0.45	GO:0006366	transcription by RNA polymerase II
0.45	GO:1902680	positive regulation of RNA biosynthetic process
0.43	GO:0009653	anatomical structure morphogenesis
0.36	GO:0010870	positive regulation of receptor biosynthetic process
0.36	GO:0045647	negative regulation of erythrocyte differentiation

0.65	GO:0043565	sequence-specific DNA binding
0.59	GO:0003700	DNA binding transcription factor activity
0.49	GO:0071837	HMG box domain binding
0.48	GO:0035326	enhancer binding
0.46	GO:0001012	RNA polymerase II regulatory region DNA binding
0.44	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part
0.33	GO:0005829	cytosol
0.32	GO:0043232	intracellular non-membrane-bounded organelle

tr|T1G7W9|T1G7W9_HELRO
Uncharacterized protein
Search

AKR1A1

0.38	Alcohol dehydrogenase

0.53	GO:0055114	oxidation-reduction process
0.45	GO:0042840	D-glucuronate catabolic process
0.44	GO:0019853	L-ascorbic acid biosynthetic process
0.41	GO:0046185	aldehyde catabolic process
0.34	GO:0016319	mushroom body development
0.32	GO:1901135	carbohydrate derivative metabolic process

0.54

GO:0016491

oxidoreductase activity

0.42	GO:0016324	apical plasma membrane
0.39	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.54

GO:0016491

tr|T1G7X0|T1G7X0_HELRO
Protein Wnt
Search

0.77	GO:0016055	Wnt signaling pathway
0.70	GO:0007275	multicellular organism development
0.52	GO:0007492	endoderm development
0.50	GO:0048869	cellular developmental process
0.48	GO:0009653	anatomical structure morphogenesis
0.47	GO:0032879	regulation of localization
0.42	GO:0016043	cellular component organization
0.41	GO:0007219	Notch signaling pathway
0.40	GO:0002376	immune system process
0.39	GO:0045595	regulation of cell differentiation

0.73	GO:0005102	receptor binding
0.38	GO:0030545	receptor regulator activity
0.38	GO:1990782	protein tyrosine kinase binding
0.36	GO:0019904	protein domain specific binding
0.36	GO:0044212	transcription regulatory region DNA binding
0.35	GO:0002020	protease binding

0.75	GO:0005578	proteinaceous extracellular matrix
0.42	GO:0005615	extracellular space
0.36	GO:0009986	cell surface
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|T1G7X1|T1G7X1_HELRO
Uncharacterized protein
Search

SEC22B

0.95	SEC22 homolog B, vesicle trafficking protein b

0.69	GO:0016192	vesicle-mediated transport
0.52	GO:1902902	negative regulation of autophagosome assembly
0.48	GO:0045732	positive regulation of protein catabolic process
0.47	GO:0090174	organelle membrane fusion
0.46	GO:0016050	vesicle organization
0.45	GO:0032940	secretion by cell
0.42	GO:0046907	intracellular transport
0.41	GO:0015031	protein transport
0.40	GO:0198738	cell-cell signaling by wnt
0.39	GO:0002790	peptide secretion

0.46	GO:0005484	SNAP receptor activity
0.46	GO:0000149	SNARE binding
0.34	GO:0004326	tetrahydrofolylpolyglutamate synthase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.51	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.49	GO:0012507	ER to Golgi transport vesicle membrane
0.47	GO:0031201	SNARE complex
0.46	GO:0000139	Golgi membrane
0.45	GO:0005789	endoplasmic reticulum membrane
0.41	GO:0042470	melanosome
0.34	GO:0030670	phagocytic vesicle membrane
0.34	GO:0070382	exocytic vesicle
0.30	GO:0016021	integral component of membrane

0.34

EC:6.3.2.17

GO:0004326

tr|T1G7X2|T1G7X2_HELRO
Uncharacterized protein
Search

0.61	GO:0010305	leaf vascular tissue pattern formation
0.57	GO:0009793	embryo development ending in seed dormancy
0.57	GO:0048364	root development
0.53	GO:0016310	phosphorylation
0.45	GO:0009926	auxin polar transport
0.44	GO:0001708	cell fate specification
0.44	GO:0019827	stem cell population maintenance

0.55	GO:0016301	kinase activity
0.39	GO:0008270	zinc ion binding
0.36	GO:0003676	nucleic acid binding

0.46	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

tr|T1G7X3|T1G7X3_HELRO
Uncharacterized protein
Search

tr|T1G7X4|T1G7X4_HELRO
Uncharacterized protein
Search

0.53	Electroneutral potassium-chloride cotransporter 1

0.84	GO:0071477	cellular hypotonic salinity response
0.76	GO:1902476	chloride transmembrane transport
0.47	GO:0007268	chemical synaptic transmission
0.41	GO:0007638	mechanosensory behavior
0.39	GO:0006884	cell volume homeostasis
0.38	GO:0071805	potassium ion transmembrane transport
0.37	GO:0030644	cellular chloride ion homeostasis
0.36	GO:0040040	thermosensory behavior
0.36	GO:0060996	dendritic spine development
0.36	GO:0035264	multicellular organism growth

0.85	GO:0015379	potassium:chloride symporter activity
0.40	GO:0022820	potassium ion symporter activity
0.36	GO:0019901	protein kinase binding
0.34	GO:0015171	amino acid transmembrane transporter activity

0.66	GO:0005887	integral component of plasma membrane
0.40	GO:0043025	neuronal cell body
0.40	GO:0043005	neuron projection
0.35	GO:0120038	plasma membrane bounded cell projection part

tr|T1G7X5|T1G7X5_HELRO
Uncharacterized protein
Search

tr|T1G7X6|T1G7X6_HELRO
Uncharacterized protein
Search

CNGA2

0.89	Cyclic nucleotide gated channel A alpha subunit

0.59	GO:0034220	ion transmembrane transport
0.56	GO:0071804	cellular potassium ion transport
0.47	GO:0007600	sensory perception
0.45	GO:0042391	regulation of membrane potential
0.35	GO:0019935	cyclic-nucleotide-mediated signaling
0.35	GO:0060271	cilium assembly
0.35	GO:0034765	regulation of ion transmembrane transport
0.34	GO:0051290	protein heterotetramerization
0.34	GO:0051289	protein homotetramerization

0.69	GO:0005216	ion channel activity
0.57	GO:0022832	voltage-gated channel activity
0.56	GO:0015079	potassium ion transmembrane transporter activity
0.40	GO:0022834	ligand-gated channel activity
0.40	GO:0030551	cyclic nucleotide binding
0.38	GO:0005516	calmodulin binding
0.35	GO:0032561	guanyl ribonucleotide binding
0.35	GO:0043168	anion binding
0.34	GO:0032559	adenyl ribonucleotide binding

0.42	GO:0005887	integral component of plasma membrane
0.38	GO:0017071	intracellular cyclic nucleotide activated cation channel complex
0.36	GO:0060170	ciliary membrane
0.35	GO:0097458	neuron part
0.34	GO:0097731	9+0 non-motile cilium
0.34	GO:0044297	cell body
0.34	GO:0030660	Golgi-associated vesicle membrane
0.33	GO:0000139	Golgi membrane

tr|T1G7X7|T1G7X7_HELRO
Uncharacterized protein
Search

tr|T1G7X8|T1G7X8_HELRO
Uncharacterized protein
Search

0.59	Calcitonin receptor N-terminal deletion splice variant

0.71	GO:0007166	cell surface receptor signaling pathway
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.40	GO:0030316	osteoclast differentiation
0.39	GO:0030279	negative regulation of ossification
0.39	GO:0043488	regulation of mRNA stability
0.39	GO:0019933	cAMP-mediated signaling
0.39	GO:0007204	positive regulation of cytosolic calcium ion concentration

0.78

GO:0004948

calcitonin receptor activity

0.52	GO:0005886	plasma membrane
0.39	GO:0001669	acrosomal vesicle
0.38	GO:0005929	cilium
0.30	GO:0016021	integral component of membrane

tr|T1G7X9|T1G7X9_HELRO
Proteasome subunit beta type
Search

0.53	Proteasome subunit beta type

0.75	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.37	GO:0010363	regulation of plant-type hypersensitive response
0.37	GO:0010043	response to zinc ion
0.36	GO:0009651	response to salt stress

0.77	GO:0070003	threonine-type peptidase activity
0.65	GO:0004175	endopeptidase activity

0.76	GO:0005839	proteasome core complex
0.56	GO:0005634	nucleus
0.45	GO:0005737	cytoplasm
0.35	GO:0098805	whole membrane
0.35	GO:0098588	bounding membrane of organelle
0.33	GO:0044446	intracellular organelle part

tr|T1G7Y0|T1G7Y0_HELRO
Uncharacterized protein
Search

0.54	GO:0009214	cyclic nucleotide catabolic process
0.42	GO:0032474	otolith morphogenesis
0.41	GO:0061371	determination of heart left/right asymmetry
0.40	GO:0060271	cilium assembly
0.37	GO:0098869	cellular oxidant detoxification
0.34	GO:0055114	oxidation-reduction process
0.34	GO:0035556	intracellular signal transduction

0.52	GO:0004113	2',3'-cyclic-nucleotide 3'-phosphodiesterase activity
0.39	GO:0004096	catalase activity
0.36	GO:0020037	heme binding
0.36	GO:0005515	protein binding

0.47	GO:0005737	cytoplasm
0.45	GO:0005856	cytoskeleton
0.45	GO:0042995	cell projection
0.30	GO:0016020	membrane

0.52

EC:3.1.4.37

GO:0004113

tr|T1G7Y1|T1G7Y1_HELRO
Uncharacterized protein
Search

0.44	Homeotic protein distal-less-like

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.35	GO:0007487	analia development
0.35	GO:0035213	clypeo-labral disc development
0.35	GO:0021553	olfactory nerve development
0.35	GO:0007479	leg disc proximal/distal pattern formation
0.35	GO:0048264	determination of ventral identity
0.35	GO:0007485	imaginal disc-derived male genitalia development
0.35	GO:0007469	antennal development

0.64

GO:0043565

sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|T1G7Y2|T1G7Y2_HELRO
Uncharacterized protein
Search

0.53	GO:0055085	transmembrane transport
0.48	GO:0006862	nucleotide transport
0.45	GO:0006839	mitochondrial transport
0.44	GO:1901264	carbohydrate derivative transport
0.43	GO:0015711	organic anion transport
0.41	GO:0015893	drug transport
0.39	GO:0072348	sulfur compound transport
0.35	GO:0051181	cofactor transport
0.34	GO:0072337	modified amino acid transport
0.34	GO:0051180	vitamin transport

0.60	GO:0005509	calcium ion binding
0.48	GO:0015215	nucleotide transmembrane transporter activity
0.45	GO:1901505	carbohydrate derivative transmembrane transporter activity
0.44	GO:0008514	organic anion transmembrane transporter activity
0.42	GO:0015238	drug transmembrane transporter activity
0.39	GO:1901682	sulfur compound transmembrane transporter activity
0.35	GO:0051184	cofactor transmembrane transporter activity
0.34	GO:0072349	modified amino acid transmembrane transporter activity
0.34	GO:0090482	vitamin transmembrane transporter activity
0.34	GO:0015318	inorganic molecular entity transmembrane transporter activity

0.43	GO:0031966	mitochondrial membrane
0.43	GO:0019866	organelle inner membrane
0.36	GO:0033391	chromatoid body
0.35	GO:0005815	microtubule organizing center
0.34	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|T1G7Y3|T1G7Y3_HELRO
Uncharacterized protein
Search

tr|T1G7Y4|T1G7Y4_HELRO
Uncharacterized protein
Search

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.52	GO:0030218	erythrocyte differentiation
0.52	GO:0030217	T cell differentiation
0.51	GO:0001525	angiogenesis
0.51	GO:0043010	camera-type eye development
0.48	GO:0006366	transcription by RNA polymerase II
0.48	GO:1902680	positive regulation of RNA biosynthetic process
0.35	GO:0031061	negative regulation of histone methylation

0.54	GO:0003677	DNA binding
0.52	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.51	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.48	GO:0046982	protein heterodimerization activity
0.44	GO:0003785	actin monomer binding
0.42	GO:0051015	actin filament binding
0.42	GO:0001067	regulatory region nucleic acid binding

0.60	GO:0005634	nucleus
0.48	GO:0005667	transcription factor complex
0.43	GO:0045171	intercellular bridge
0.41	GO:0015629	actin cytoskeleton
0.40	GO:0015630	microtubule cytoskeleton
0.39	GO:0043233	organelle lumen
0.39	GO:0005737	cytoplasm
0.37	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

tr|T1G7Y5|T1G7Y5_HELRO
Uncharacterized protein
Search

0.69	Putative syntaxin-binding protein 2 (Fragment)

0.43	GO:0006887	exocytosis
0.38	GO:0051641	cellular localization
0.38	GO:0022406	membrane docking
0.37	GO:0023052	signaling
0.37	GO:0007154	cell communication
0.36	GO:0006470	protein dephosphorylation
0.36	GO:0065007	biological regulation
0.36	GO:0008104	protein localization
0.35	GO:0032502	developmental process
0.35	GO:0051716	cellular response to stimulus

0.38	GO:0005509	calcium ion binding
0.37	GO:0005515	protein binding
0.37	GO:0004721	phosphoprotein phosphatase activity
0.36	GO:0030234	enzyme regulator activity
0.35	GO:0005249	voltage-gated potassium channel activity
0.34	GO:0004672	protein kinase activity
0.34	GO:0003676	nucleic acid binding
0.34	GO:0016849	phosphorus-oxygen lyase activity
0.33	GO:0000166	nucleotide binding
0.33	GO:0044877	macromolecular complex binding

0.40	GO:0000145	exocyst
0.35	GO:0000159	protein phosphatase type 2A complex
0.35	GO:0008076	voltage-gated potassium channel complex
0.35	GO:0048786	presynaptic active zone
0.34	GO:0005634	nucleus
0.34	GO:0030131	clathrin adaptor complex
0.34	GO:0005829	cytosol
0.33	GO:0005576	extracellular region

0.37	EC:3.1.3.16	GO:0004721
0.33	KEGG:R00630	GO:0052689

tr|T1G7Y6|T1G7Y6_HELRO
Uncharacterized protein
Search

0.66	ATP-binding cassette sub-family A member 1-like

0.53	GO:0055085	transmembrane transport
0.38	GO:0006869	lipid transport
0.34	GO:0006638	neutral lipid metabolic process
0.34	GO:0015709	thiosulfate transport
0.34	GO:0099133	ATP hydrolysis coupled anion transmembrane transport
0.33	GO:0008272	sulfate transport
0.32	GO:0015716	organic phosphonate transport
0.32	GO:0015748	organophosphate ester transport

0.64	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0015117	thiosulfate transmembrane transporter activity
0.33	GO:0015116	sulfate transmembrane transporter activity
0.32	GO:0015604	organic phosphonate transmembrane transporter activity
0.32	GO:0015605	organophosphate ester transmembrane transporter activity

0.35	GO:0043231	intracellular membrane-bounded organelle
0.33	GO:0012505	endomembrane system
0.32	GO:0044444	cytoplasmic part
0.30	GO:0016020	membrane

tr|T1G7Y7|T1G7Y7_HELRO
Uncharacterized protein
Search

0.70	GO:0045900	negative regulation of translational elongation
0.46	GO:0055085	transmembrane transport
0.39	GO:0060155	platelet dense granule organization
0.39	GO:0038027	apolipoprotein A-I-mediated signaling pathway
0.39	GO:0050702	interleukin-1 beta secretion
0.39	GO:0032489	regulation of Cdc42 protein signal transduction
0.39	GO:0034380	high-density lipoprotein particle assembly
0.39	GO:0034616	response to laminar fluid shear stress
0.38	GO:0033700	phospholipid efflux
0.38	GO:0055091	phospholipid homeostasis

0.61	GO:0016887	ATPase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0015399	primary active transmembrane transporter activity
0.39	GO:0034188	apolipoprotein A-I receptor activity
0.39	GO:0034186	apolipoprotein A-I binding
0.39	GO:0008525	phosphatidylcholine transporter activity
0.38	GO:0017127	cholesterol transporter activity
0.38	GO:0051117	ATPase binding

0.38	GO:0045335	phagocytic vesicle
0.37	GO:0009897	external side of plasma membrane
0.37	GO:0045121	membrane raft
0.37	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0005794	Golgi apparatus
0.35	GO:0005887	integral component of plasma membrane

0.61

GO:0016887

tr|T1G7Y8|T1G7Y8_HELRO
Uncharacterized protein
Search

tr|T1G7Y9|T1G7Y9_HELRO
Uncharacterized protein
Search

0.58	GO:2000691	negative regulation of cardiac muscle cell myoblast differentiation
0.53	GO:0001843	neural tube closure
0.53	GO:0060976	coronary vasculature development
0.53	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.53	GO:0035904	aorta development
0.53	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.52	GO:0031398	positive regulation of protein ubiquitination
0.51	GO:0006606	protein import into nucleus
0.47	GO:0045892	negative regulation of transcription, DNA-templated
0.46	GO:0021535	cell migration in hindbrain

0.63	GO:0008270	zinc ion binding
0.37	GO:0005515	protein binding

0.51	GO:0031965	nuclear membrane
0.46	GO:0005829	cytosol
0.34	GO:0005886	plasma membrane

tr|T1G7Z0|T1G7Z0_HELRO
Uncharacterized protein
Search

0.69	GO:0048496	maintenance of animal organ identity
0.66	GO:0045494	photoreceptor cell maintenance
0.65	GO:0035315	hair cell differentiation
0.65	GO:0060113	inner ear receptor cell differentiation
0.62	GO:0007605	sensory perception of sound
0.60	GO:0050953	sensory perception of light stimulus
0.52	GO:0045184	establishment of protein localization
0.48	GO:0007155	cell adhesion
0.43	GO:0040012	regulation of locomotion
0.41	GO:0048666	neuron development

0.64	GO:0017022	myosin binding
0.63	GO:0005518	collagen binding
0.58	GO:0042803	protein homodimerization activity
0.38	GO:0005102	receptor binding
0.38	GO:0005201	extracellular matrix structural constituent
0.34	GO:0050839	cell adhesion molecule binding
0.32	GO:0008270	zinc ion binding

0.70	GO:0060171	stereocilium membrane
0.70	GO:0002142	stereocilia ankle link complex
0.70	GO:1990696	USH2 complex
0.68	GO:1990075	periciliary membrane compartment
0.66	GO:0001917	photoreceptor inner segment
0.65	GO:0032391	photoreceptor connecting cilium
0.64	GO:0005604	basement membrane
0.63	GO:0036064	ciliary basal body
0.62	GO:0016324	apical plasma membrane
0.42	GO:0005737	cytoplasm

tr|T1G7Z1|T1G7Z1_HELRO
Uncharacterized protein
Search

tr|T1G7Z2|T1G7Z2_HELRO
Uncharacterized protein
Search

RPS29

0.82	Small subunit ribosomal protein S29e

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.44	GO:0060218	hematopoietic stem cell differentiation
0.43	GO:0048821	erythrocyte development
0.43	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator
0.43	GO:0001570	vasculogenesis
0.42	GO:0001525	angiogenesis
0.42	GO:0043009	chordate embryonic development

0.64	GO:0003735	structural constituent of ribosome
0.43	GO:0008270	zinc ion binding
0.41	GO:0003723	RNA binding
0.32	GO:0016787	hydrolase activity

0.61	GO:0005840	ribosome
0.49	GO:0044445	cytosolic part
0.46	GO:0005844	polysome
0.45	GO:0044446	intracellular organelle part
0.40	GO:0005791	rough endoplasmic reticulum
0.39	GO:0098562	cytoplasmic side of membrane
0.38	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.38	GO:0098588	bounding membrane of organelle
0.35	GO:0005925	focal adhesion
0.35	GO:0070062	extracellular exosome

0.32

GO:0016787

tr|T1G7Z3|T1G7Z3_HELRO
Uncharacterized protein
Search

0.55	GO:0055085	transmembrane transport
0.42	GO:0008643	carbohydrate transport
0.34	GO:0098657	import into cell
0.33	GO:0015992	proton transport

0.57

GO:0022857

transmembrane transporter activity

0.30

GO:0044425

membrane part

tr|T1G7Z4|T1G7Z4_HELRO
Uncharacterized protein
Search

0.11	Vacuolar protein sorting-associated protein 33B

0.80	GO:0006904	vesicle docking involved in exocytosis
0.40	GO:0035622	intrahepatic bile duct development
0.36	GO:0015031	protein transport

0.40	GO:0005774	vacuolar membrane
0.39	GO:0000325	plant-type vacuole
0.38	GO:0031902	late endosome membrane
0.38	GO:0005764	lysosome
0.36	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

tr|T1G7Z5|T1G7Z5_HELRO
Uncharacterized protein
Search

tr|T1G7Z6|T1G7Z6_HELRO
Nuclear cap-binding protein subunit 2
Search

0.71	Nuclear cap-binding protein subunit 2

0.82	GO:0045292	mRNA cis splicing, via spliceosome
0.44	GO:0031047	gene silencing by RNA
0.41	GO:0006408	snRNA export from nucleus
0.41	GO:0046833	positive regulation of RNA export from nucleus
0.40	GO:0006417	regulation of translation
0.40	GO:0045071	negative regulation of viral genome replication
0.39	GO:0031050	dsRNA fragmentation
0.39	GO:0016441	posttranscriptional gene silencing
0.39	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.38	GO:0034249	negative regulation of cellular amide metabolic process

0.82	GO:0000339	RNA cap binding
0.39	GO:0017069	snRNA binding
0.38	GO:0003729	mRNA binding

0.83	GO:0005846	nuclear cap binding complex
0.61	GO:0005634	nucleus
0.34	GO:0044446	intracellular organelle part
0.34	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0005737	cytoplasm
0.33	GO:0012505	endomembrane system
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0031975	envelope
0.30	GO:0016020	membrane

tr|T1G7Z7|T1G7Z7_HELRO
Uncharacterized protein
Search

TMEM41B

0.63	Transmembrane protein 41B

0.44

GO:0008045

motor neuron axon guidance

0.30

GO:0044425

membrane part

tr|T1G7Z8|T1G7Z8_HELRO
Uncharacterized protein
Search

0.76	Dopamine receptor I

0.75	GO:0007212	dopamine receptor signaling pathway
0.65	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.55	GO:0042311	vasodilation
0.44	GO:0007612	learning
0.41	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.41	GO:0033861	negative regulation of NAD(P)H oxidase activity
0.41	GO:0060292	long term synaptic depression
0.41	GO:0001993	regulation of systemic arterial blood pressure by norepinephrine-epinephrine
0.41	GO:0001975	response to amphetamine
0.41	GO:0001992	regulation of systemic arterial blood pressure by vasopressin

0.76	GO:0004952	dopamine neurotransmitter receptor activity
0.50	GO:0008227	G-protein coupled amine receptor activity
0.41	GO:0099528	G-protein coupled neurotransmitter receptor activity
0.41	GO:1901338	catecholamine binding
0.39	GO:0070405	ammonium ion binding
0.37	GO:0008528	G-protein coupled peptide receptor activity
0.36	GO:0099589	serotonin receptor activity
0.34	GO:0008144	drug binding
0.34	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.32	GO:0015464	acetylcholine receptor activity

0.60	GO:0005887	integral component of plasma membrane
0.40	GO:0060170	ciliary membrane
0.40	GO:0005622	intracellular
0.40	GO:0031526	brush border membrane
0.40	GO:0097730	non-motile cilium
0.34	GO:0098793	presynapse
0.34	GO:0012505	endomembrane system
0.33	GO:0045211	postsynaptic membrane
0.32	GO:0031301	integral component of organelle membrane
0.32	GO:0012506	vesicle membrane

0.34

GO:0004715

tr|T1G7Z9|T1G7Z9_HELRO
Uncharacterized protein
Search

tr|T1G800|T1G800_HELRO
Uncharacterized protein
Search

0.74	GO:0016579	protein deubiquitination
0.70	GO:0006511	ubiquitin-dependent protein catabolic process
0.46	GO:0034394	protein localization to cell surface
0.45	GO:0000244	spliceosomal tri-snRNP complex assembly
0.45	GO:0031397	negative regulation of protein ubiquitination
0.43	GO:0031647	regulation of protein stability
0.43	GO:0034122	negative regulation of toll-like receptor signaling pathway
0.33	GO:0030001	metal ion transport
0.33	GO:0016042	lipid catabolic process
0.33	GO:0072511	divalent inorganic cation transport

0.74	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.47	GO:0031685	adenosine receptor binding
0.42	GO:0042802	identical protein binding
0.34	GO:0005509	calcium ion binding
0.34	GO:0004435	phosphatidylinositol phospholipase C activity
0.34	GO:0046873	metal ion transmembrane transporter activity
0.34	GO:0008270	zinc ion binding
0.33	GO:0005261	cation channel activity
0.33	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.33	GO:0004871	signal transducer activity

0.41	GO:0005829	cytosol
0.40	GO:0005634	nucleus
0.37	GO:0005886	plasma membrane
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0005694	chromosome
0.33	GO:0044446	intracellular organelle part
0.32	GO:0005856	cytoskeleton
0.30	GO:0016021	integral component of membrane

0.74	EC:3.4.19.12	GO:0036459
0.34	KEGG:R03435	GO:0004435

tr|T1G801|T1G801_HELRO
1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase
Search

0.73	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase

0.76	GO:0019509	L-methionine salvage from methylthioadenosine
0.52	GO:0055114	oxidation-reduction process
0.36	GO:2000243	positive regulation of reproductive process
0.35	GO:0051302	regulation of cell division
0.34	GO:0016310	phosphorylation
0.33	GO:0005975	carbohydrate metabolic process
0.33	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:0010468	regulation of gene expression

0.82	GO:0010309	acireductone dioxygenase [iron(II)-requiring] activity
0.60	GO:0005506	iron ion binding
0.35	GO:0010308	acireductone dioxygenase (Ni2+-requiring) activity
0.35	GO:0016868	intramolecular transferase activity, phosphotransferases
0.34	GO:0016301	kinase activity
0.34	GO:0000287	magnesium ion binding
0.34	GO:0043565	sequence-specific DNA binding
0.33	GO:0003700	DNA binding transcription factor activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding

0.60	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.39	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.82	EC:1.13.11.54	GO:0010309
0.82	KEGG:R07364	GO:0010309

tr|T1G802|T1G802_HELRO
Uncharacterized protein
Search

0.30

GO:0044425

membrane part

tr|T1G803|T1G803_HELRO
Uncharacterized protein
Search

0.44	Calcium-binding EF-hand

0.47	GO:0006468	protein phosphorylation
0.43	GO:0051300	spindle pole body organization
0.43	GO:1903525	regulation of membrane tubulation
0.42	GO:0031321	ascospore-type prospore assembly
0.42	GO:0042991	transcription factor import into nucleus
0.42	GO:0000742	karyogamy involved in conjugation with cellular fusion
0.41	GO:0006607	NLS-bearing protein import into nucleus
0.41	GO:0016237	lysosomal microautophagy
0.41	GO:0007114	cell budding
0.41	GO:0042144	vacuole fusion, non-autophagic

0.70	GO:0005509	calcium ion binding
0.48	GO:0004672	protein kinase activity
0.43	GO:0030554	adenyl nucleotide binding
0.42	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0032555	purine ribonucleotide binding
0.42	GO:0008144	drug binding
0.42	GO:0051019	mitogen-activated protein kinase binding
0.41	GO:0048306	calcium-dependent protein binding
0.37	GO:0008897	holo-[acyl-carrier-protein] synthase activity
0.36	GO:0005516	calmodulin binding

0.43	GO:0005823	central plaque of spindle pole body
0.42	GO:0043332	mating projection tip
0.42	GO:0045160	myosin I complex
0.42	GO:0051286	cell tip
0.41	GO:0032155	cell division site part
0.41	GO:0000131	incipient cellular bud site
0.41	GO:0005628	prospore membrane
0.41	GO:0005934	cellular bud tip
0.40	GO:0005935	cellular bud neck
0.40	GO:0099738	cell cortex region

0.37

EC:2.7.8.7

GO:0008897

tr|T1G804|T1G804_HELRO
Uncharacterized protein
Search

tr|T1G805|T1G805_HELRO
Uncharacterized protein
Search

0.84	GO:0051382	kinetochore assembly
0.59	GO:0000278	mitotic cell cycle
0.57	GO:0007059	chromosome segregation
0.51	GO:0051303	establishment of chromosome localization
0.50	GO:0007127	meiosis I
0.39	GO:0051301	cell division
0.39	GO:0034080	CENP-A containing nucleosome assembly

0.85	GO:0019237	centromeric DNA binding
0.35	GO:0005515	protein binding

0.78	GO:0000776	kinetochore
0.66	GO:0005721	pericentric heterochromatin
0.66	GO:0090543	Flemming body
0.64	GO:0032154	cleavage furrow
0.63	GO:0045171	intercellular bridge
0.62	GO:0000779	condensed chromosome, centromeric region
0.61	GO:0000794	condensed nuclear chromosome
0.59	GO:0016604	nuclear body
0.58	GO:0044454	nuclear chromosome part
0.53	GO:0005829	cytosol

tr|T1G806|T1G806_HELRO
Uncharacterized protein
Search

0.73	GO:0050767	regulation of neurogenesis
0.68	GO:0007155	cell adhesion
0.48	GO:0007596	blood coagulation
0.42	GO:0042127	regulation of cell proliferation
0.38	GO:0006508	proteolysis

0.39

GO:0008233

peptidase activity

0.70

GO:0031012

extracellular matrix

0.39

GO:0008233

tr|T1G807|T1G807_HELRO
Uncharacterized protein
Search

0.50	GO:0007160	cell-matrix adhesion
0.46	GO:0007165	signal transduction
0.43	GO:0006468	protein phosphorylation
0.37	GO:0055085	transmembrane transport

0.46	GO:0004930	G-protein coupled receptor activity
0.45	GO:0005509	calcium ion binding
0.43	GO:0004672	protein kinase activity
0.40	GO:0030554	adenyl nucleotide binding
0.39	GO:0097367	carbohydrate derivative binding
0.39	GO:0008144	drug binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0022857	transmembrane transporter activity
0.37	GO:0003676	nucleic acid binding

0.30

GO:0044425

membrane part

tr|T1G808|T1G808_HELRO
Uncharacterized protein
Search

0.58	GSX-ANTP class homeobox protein (Fragment)

0.52	GO:1903506	regulation of nucleic acid-templated transcription
0.52	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.51	GO:0010468	regulation of gene expression
0.46	GO:0030903	notochord development
0.46	GO:0044458	motile cilium assembly
0.46	GO:1902017	regulation of cilium assembly
0.46	GO:0001947	heart looping
0.45	GO:0009880	embryonic pattern specification
0.45	GO:0009953	dorsal/ventral pattern formation
0.34	GO:0006351	transcription, DNA-templated

0.58	GO:0043565	sequence-specific DNA binding
0.37	GO:0008289	lipid binding
0.35	GO:0004000	adenosine deaminase activity
0.33	GO:0003700	DNA binding transcription factor activity

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.35

GO:0004000

tr|T1G810|T1G810_HELRO
Uncharacterized protein
Search

0.61	Microfibril-associated glycoprotein 4

0.62	GO:0042060	wound healing
0.62	GO:0007599	hemostasis
0.62	GO:0050817	coagulation
0.55	GO:0001775	cell activation
0.54	GO:0051258	protein polymerization
0.46	GO:0007165	signal transduction
0.41	GO:0009888	tissue development
0.41	GO:0035634	response to stilbenoid
0.40	GO:0031099	regeneration
0.39	GO:0008203	cholesterol metabolic process

0.56	GO:0030674	protein binding, bridging
0.52	GO:0005102	receptor binding
0.39	GO:0090729	toxin activity
0.38	GO:0030234	enzyme regulator activity
0.37	GO:0004222	metalloendopeptidase activity
0.36	GO:0008061	chitin binding
0.36	GO:0005509	calcium ion binding
0.36	GO:0008270	zinc ion binding

0.60	GO:0005577	fibrinogen complex
0.39	GO:1905369	endopeptidase complex
0.33	GO:0044424	intracellular part
0.30	GO:0031224	intrinsic component of membrane

0.37

GO:0004222

tr|T1G811|T1G811_HELRO
Uncharacterized protein
Search

CPNE2

0.95

Copine II

0.74	GO:0071277	cellular response to calcium ion
0.65	GO:1903861	positive regulation of dendrite extension
0.36	GO:0035335	peptidyl-tyrosine dephosphorylation

0.36	GO:0004725	protein tyrosine phosphatase activity
0.35	GO:0005515	protein binding

0.54	GO:0005634	nucleus
0.50	GO:0005886	plasma membrane
0.45	GO:0070062	extracellular exosome
0.44	GO:0005737	cytoplasm
0.40	GO:0097708	intracellular vesicle

0.36

GO:0004725

tr|T1G812|T1G812_HELRO
Uncharacterized protein
Search

TSNAX

0.72	Translin-associated protein X

0.33

GO:0010952

positive regulation of peptidase activity

0.65	GO:0043565	sequence-specific DNA binding
0.33	GO:0070577	lysine-acetylated histone binding
0.33	GO:0016504	peptidase activator activity
0.33	GO:0070628	proteasome binding

0.38	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm

tr|T1G813|T1G813_HELRO
Uncharacterized protein
Search

tr|T1G814|T1G814_HELRO
Nuclear pore protein
Search

NUP93

0.72	Nuclear pore complex protein Nup93

0.76	GO:0051028	mRNA transport
0.65	GO:0015031	protein transport
0.54	GO:0051292	nuclear pore complex assembly
0.51	GO:0090521	glomerular visceral epithelial cell migration
0.51	GO:0060391	positive regulation of SMAD protein import into nucleus
0.50	GO:0072015	glomerular visceral epithelial cell development
0.50	GO:1903206	negative regulation of hydrogen peroxide-induced cell death
0.49	GO:0060395	SMAD protein signal transduction
0.49	GO:0006998	nuclear envelope organization
0.45	GO:0071166	ribonucleoprotein complex localization

0.80	GO:0017056	structural constituent of nuclear pore
0.33	GO:0005515	protein binding
0.32	GO:0017154	semaphorin receptor activity

0.78	GO:0005643	nuclear pore
0.48	GO:0034399	nuclear periphery
0.48	GO:0031965	nuclear membrane
0.34	GO:0005783	endoplasmic reticulum
0.33	GO:0019028	viral capsid
0.33	GO:0043657	host cell
0.30	GO:0044425	membrane part

tr|T1G815|T1G815_HELRO
Ribokinase
Search

RBKS

0.52	Ribokinase

0.79	GO:0006014	D-ribose metabolic process
0.74	GO:0019323	pentose catabolic process
0.74	GO:0046835	carbohydrate phosphorylation
0.34	GO:0006098	pentose-phosphate shunt

0.80	GO:0004747	ribokinase activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.58	GO:0005634	nucleus
0.47	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome

0.80

EC:2.7.1.15

GO:0004747

tr|T1G816|T1G816_HELRO
DNA polymerase
Search

0.48	DNA polymerase

0.67	GO:0071897	DNA biosynthetic process
0.66	GO:0006260	DNA replication
0.64	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.51	GO:0006287	base-excision repair, gap-filling
0.46	GO:0006297	nucleotide-excision repair, DNA gap filling
0.39	GO:0055089	fatty acid homeostasis
0.38	GO:0034644	cellular response to UV
0.35	GO:0042769	DNA damage response, detection of DNA damage
0.34	GO:0006301	postreplication repair
0.34	GO:0006283	transcription-coupled nucleotide-excision repair

0.72	GO:0008408	3'-5' exonuclease activity
0.71	GO:0003887	DNA-directed DNA polymerase activity
0.66	GO:0051539	4 iron, 4 sulfur cluster binding
0.55	GO:0003677	DNA binding
0.53	GO:0046872	metal ion binding
0.53	GO:1901265	nucleoside phosphate binding
0.51	GO:0036094	small molecule binding
0.42	GO:0016895	exodeoxyribonuclease activity, producing 5'-phosphomonoesters
0.41	GO:0019899	enzyme binding
0.37	GO:0003682	chromatin binding

0.60	GO:0005634	nucleus
0.46	GO:0016235	aggresome
0.43	GO:0031974	membrane-enclosed lumen
0.42	GO:0030894	replisome
0.42	GO:0042575	DNA polymerase complex
0.41	GO:0005829	cytosol
0.36	GO:0000781	chromosome, telomeric region
0.36	GO:1990391	DNA repair complex
0.34	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.71

EC:2.7.7.7

GO:0003887

tr|T1G817|T1G817_HELRO
Uncharacterized protein
Search

OSGIN1

0.57	Oxidative stress-induced growth inhibitor 1

0.81	GO:0030308	negative regulation of cell growth
0.73	GO:0043065	positive regulation of apoptotic process
0.63	GO:0010469	regulation of receptor activity
0.47	GO:0055114	oxidation-reduction process
0.36	GO:0030154	cell differentiation
0.36	GO:0007275	multicellular organism development
0.35	GO:0051321	meiotic cell cycle
0.34	GO:0009116	nucleoside metabolic process
0.33	GO:0055085	transmembrane transport

0.65	GO:0008083	growth factor activity
0.47	GO:0016491	oxidoreductase activity
0.33	GO:0022857	transmembrane transporter activity

0.30

GO:0031224

intrinsic component of membrane

0.47

GO:0016491

tr|T1G818|T1G818_HELRO
Rhomboid-like protein
Search

0.56	Inactive rhomboid protein 1

0.61	GO:0006508	proteolysis
0.51	GO:0050708	regulation of protein secretion
0.51	GO:0042058	regulation of epidermal growth factor receptor signaling pathway
0.50	GO:0002792	negative regulation of peptide secretion
0.50	GO:1903531	negative regulation of secretion by cell
0.50	GO:0051224	negative regulation of protein transport
0.44	GO:0061136	regulation of proteasomal protein catabolic process
0.44	GO:0008283	cell proliferation
0.43	GO:0016477	cell migration
0.43	GO:0051604	protein maturation

0.69	GO:0004252	serine-type endopeptidase activity
0.37	GO:0019838	growth factor binding
0.33	GO:0003964	RNA-directed DNA polymerase activity

0.48	GO:0005789	endoplasmic reticulum membrane
0.42	GO:0000139	Golgi membrane
0.37	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0004252

tr|T1G819|T1G819_HELRO
Uncharacterized protein
Search

0.54	Chromatin modification-related protein MEAF6

0.78	GO:0016573	histone acetylation
0.36	GO:0006351	transcription, DNA-templated
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression
0.35	GO:1901796	regulation of signal transduction by p53 class mediator

0.33

GO:0005515

protein binding

0.76	GO:0000123	histone acetyltransferase complex
0.48	GO:0000776	kinetochore
0.46	GO:0005730	nucleolus
0.40	GO:0000779	condensed chromosome, centromeric region
0.30	GO:0016020	membrane

tr|T1G820|T1G820_HELRO
Uncharacterized protein
Search

tr|T1G821|T1G821_HELRO
Uncharacterized protein
Search

0.72	Potassium voltage-gated channel protein Shaker

0.77	GO:0051260	protein homooligomerization
0.76	GO:0034765	regulation of ion transmembrane transport
0.73	GO:0071805	potassium ion transmembrane transport
0.44	GO:0086052	membrane repolarization during SA node cell action potential
0.44	GO:0086050	membrane repolarization during bundle of His cell action potential
0.43	GO:0098914	membrane repolarization during atrial cardiac muscle cell action potential
0.43	GO:0060081	membrane hyperpolarization
0.42	GO:0086091	regulation of heart rate by cardiac conduction
0.41	GO:0043267	negative regulation of potassium ion transport
0.41	GO:0019229	regulation of vasoconstriction

0.78	GO:0005249	voltage-gated potassium channel activity
0.47	GO:0030955	potassium ion binding
0.42	GO:0051393	alpha-actinin binding
0.42	GO:0097110	scaffold protein binding
0.42	GO:0019870	potassium channel inhibitor activity
0.40	GO:0019901	protein kinase binding
0.33	GO:0005102	receptor binding

0.78	GO:0008076	voltage-gated potassium channel complex
0.42	GO:0014704	intercalated disc
0.41	GO:0045121	membrane raft
0.35	GO:0044224	juxtaparanode region of axon
0.35	GO:0033270	paranode region of axon
0.34	GO:0046691	intracellular canaliculus
0.34	GO:0030018	Z disc
0.33	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0043679	axon terminus
0.33	GO:0005794	Golgi apparatus

tr|T1G822|T1G822_HELRO
Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial
Search

OSGEPL1

0.87	Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial

0.75	GO:0002949	tRNA threonylcarbamoyladenosine modification
0.61	GO:0006508	proteolysis

0.70	GO:0004222	metalloendopeptidase activity
0.70	GO:0061711	N(6)-L-threonylcarbamoyladenine synthase
0.49	GO:0046872	metal ion binding

0.55	GO:0005739	mitochondrion
0.46	GO:0000408	EKC/KEOPS complex
0.30	GO:0031224	intrinsic component of membrane

0.70

GO:0004222

tr|T1G823|T1G823_HELRO
Uncharacterized protein
Search

0.44	GO:0048096	chromatin-mediated maintenance of transcription
0.37	GO:0007498	mesoderm development
0.37	GO:0009953	dorsal/ventral pattern formation
0.36	GO:0045944	positive regulation of transcription by RNA polymerase II
0.34	GO:0007219	Notch signaling pathway
0.33	GO:0030154	cell differentiation
0.33	GO:0050793	regulation of developmental process

0.63	GO:0008270	zinc ion binding
0.37	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.36	GO:0016874	ligase activity
0.33	GO:0005509	calcium ion binding

0.42	GO:0044454	nuclear chromosome part
0.40	GO:0000785	chromatin
0.36	GO:0005657	replication fork
0.34	GO:0005654	nucleoplasm
0.33	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.36

GO:0016874

tr|T1G824|T1G824_HELRO
Uncharacterized protein
Search

0.50

Tenascin

0.76	GO:0048514	blood vessel morphogenesis
0.70	GO:0043066	negative regulation of apoptotic process
0.67	GO:0048646	anatomical structure formation involved in morphogenesis
0.62	GO:0051005	negative regulation of lipoprotein lipase activity
0.59	GO:0070328	triglyceride homeostasis
0.54	GO:0010519	negative regulation of phospholipase activity
0.53	GO:0055091	phospholipid homeostasis
0.52	GO:0050996	positive regulation of lipid catabolic process
0.51	GO:0060840	artery development
0.51	GO:0042632	cholesterol homeostasis

0.53	GO:0004857	enzyme inhibitor activity
0.51	GO:0005178	integrin binding
0.48	GO:0008083	growth factor activity
0.45	GO:0042802	identical protein binding
0.35	GO:0003723	RNA binding

0.69	GO:0044421	extracellular region part
0.49	GO:0005769	early endosome
0.47	GO:0009986	cell surface
0.46	GO:0005794	Golgi apparatus
0.30	GO:0016020	membrane

tr|T1G825|T1G825_HELRO
Uncharacterized protein
Search

0.81	Copine VIII

0.83	GO:1903861	positive regulation of dendrite extension
0.43	GO:0000038	very long-chain fatty acid metabolic process
0.41	GO:0006635	fatty acid beta-oxidation
0.36	GO:0055085	transmembrane transport

0.38	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding

0.73	GO:0043025	neuronal cell body
0.70	GO:0043005	neuron projection
0.44	GO:0070062	extracellular exosome
0.41	GO:0005777	peroxisome
0.30	GO:0016020	membrane

tr|T1G826|T1G826_HELRO
Uncharacterized protein
Search

0.60

Macoilin

0.58	GO:0023041	neuronal signal transduction
0.50	GO:0007420	brain development

0.53	GO:0030867	rough endoplasmic reticulum membrane
0.53	GO:0044306	neuron projection terminus
0.52	GO:0031965	nuclear membrane
0.51	GO:0030424	axon
0.49	GO:0045202	synapse
0.30	GO:0031224	intrinsic component of membrane

tr|T1G827|T1G827_HELRO
Uncharacterized protein
Search

GPB-1

0.73	Guanine nucleotide-binding protein subunit beta

0.61	GO:0007165	signal transduction
0.43	GO:0046662	regulation of oviposition
0.42	GO:0000132	establishment of mitotic spindle orientation
0.41	GO:0040013	negative regulation of locomotion
0.40	GO:0009792	embryo development ending in birth or egg hatching
0.36	GO:0016573	histone acetylation
0.35	GO:0048920	posterior lateral line neuromast primordium migration
0.34	GO:0051301	cell division
0.34	GO:1901642	nucleoside transmembrane transport
0.33	GO:0006413	translational initiation

0.37	GO:0004402	histone acetyltransferase activity
0.36	GO:0004871	signal transducer activity
0.34	GO:0005516	calmodulin binding
0.34	GO:0005337	nucleoside transmembrane transporter activity
0.33	GO:0003743	translation initiation factor activity

0.34	GO:1905360	GTPase complex
0.34	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.33	GO:0098797	plasma membrane protein complex
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.37

GO:0004402

tr|T1G828|T1G828_HELRO
Uncharacterized protein
Search

0.55	GO:0055085	transmembrane transport
0.42	GO:0008643	carbohydrate transport
0.34	GO:0098657	import into cell
0.33	GO:0015992	proton transport

0.57

GO:0022857

transmembrane transporter activity

0.30

GO:0044425

membrane part

tr|T1G829|T1G829_HELRO
Uncharacterized protein
Search

tr|T1G830|T1G830_HELRO
Uncharacterized protein
Search

0.76	Receptor Mediated Endocytosis

0.60	GO:0032456	endocytic recycling
0.45	GO:1901387	positive regulation of voltage-gated calcium channel activity
0.44	GO:0086036	regulation of cardiac muscle cell membrane potential
0.44	GO:0090160	Golgi to lysosome transport
0.44	GO:1903358	regulation of Golgi organization
0.44	GO:0060271	cilium assembly
0.44	GO:0034498	early endosome to Golgi transport
0.44	GO:1903779	regulation of cardiac conduction
0.44	GO:0001881	receptor recycling
0.43	GO:0055117	regulation of cardiac muscle contraction

0.67	GO:0005509	calcium ion binding
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0019904	protein domain specific binding
0.35	GO:0016887	ATPase activity
0.32	GO:0004799	thymidylate synthase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0008144	drug binding

0.45	GO:0055038	recycling endosome membrane
0.45	GO:0020018	ciliary pocket membrane
0.42	GO:0043209	myelin sheath
0.42	GO:0030139	endocytic vesicle
0.41	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0005829	cytosol
0.34	GO:0005925	focal adhesion
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.35	EC:3.6.1.3	GO:0016887
0.32	KEGG:R02101	GO:0004799

tr|T1G831|T1G831_HELRO
Uncharacterized protein
Search

tr|T1G832|T1G832_HELRO
Uncharacterized protein
Search

TMEM184B

0.94	Transmembrane protein 184B isoform a

0.33

GO:0006468

protein phosphorylation

0.39	GO:0005215	transporter activity
0.33	GO:0004672	protein kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.34	GO:0031901	early endosome membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1G833|T1G833_HELRO
Uncharacterized protein
Search

TMX1

0.37	Novel protein containing thioredoxin domain

0.69	GO:0045454	cell redox homeostasis
0.52	GO:0034976	response to endoplasmic reticulum stress
0.43	GO:0006457	protein folding
0.38	GO:0055114	oxidation-reduction process
0.35	GO:0040032	post-embryonic body morphogenesis
0.35	GO:0042338	cuticle development involved in collagen and cuticulin-based cuticle molting cycle
0.34	GO:0040018	positive regulation of multicellular organism growth
0.34	GO:0070932	histone H3 deacetylation
0.33	GO:0006511	ubiquitin-dependent protein catabolic process
0.33	GO:1902175	regulation of oxidative stress-induced intrinsic apoptotic signaling pathway

0.48	GO:0003756	protein disulfide isomerase activity
0.45	GO:0015036	disulfide oxidoreductase activity
0.34	GO:0032041	NAD-dependent histone deacetylase activity (H3-K14 specific)
0.34	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.33	GO:0031545	peptidyl-proline 4-dioxygenase activity

0.48	GO:0005783	endoplasmic reticulum
0.45	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.44	GO:0031984	organelle subcompartment
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.48

EC:5.3.4.1

GO:0003756

tr|T1G834|T1G834_HELRO
Uncharacterized protein
Search

MTMR6

0.90	Putative phosphatidylinositol 3-phosphate 3-phosphatase myotubularin mtm1 (Fragment)

0.81	GO:0046856	phosphatidylinositol dephosphorylation
0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.53	GO:0010506	regulation of autophagy
0.46	GO:0071805	potassium ion transmembrane transport
0.35	GO:0000278	mitotic cell cycle
0.34	GO:0014065	phosphatidylinositol 3-kinase signaling
0.34	GO:0000187	activation of MAPK activity
0.34	GO:0001568	blood vessel development
0.34	GO:0000165	MAPK cascade
0.34	GO:0006661	phosphatidylinositol biosynthetic process

0.84	GO:0052866	phosphatidylinositol phosphate phosphatase activity
0.75	GO:0004725	protein tyrosine phosphatase activity
0.50	GO:0015269	calcium-activated potassium channel activity
0.42	GO:0046872	metal ion binding
0.35	GO:0004708	MAP kinase kinase activity
0.34	GO:0004722	protein serine/threonine phosphatase activity
0.33	GO:0005515	protein binding
0.32	GO:0019208	phosphatase regulator activity

0.48	GO:0005635	nuclear envelope
0.37	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.75

GO:0004725

tr|T1G835|T1G835_HELRO
Uncharacterized protein
Search

0.36	GO:0097105	presynaptic membrane assembly
0.36	GO:0097104	postsynaptic membrane assembly
0.36	GO:0007158	neuron cell-cell adhesion
0.36	GO:0048488	synaptic vesicle endocytosis
0.35	GO:0043043	peptide biosynthetic process
0.35	GO:0050804	modulation of chemical synaptic transmission
0.35	GO:0044267	cellular protein metabolic process
0.34	GO:0010467	gene expression
0.34	GO:0009059	macromolecule biosynthetic process
0.33	GO:0043547	positive regulation of GTPase activity

0.48	GO:0016787	hydrolase activity
0.36	GO:0003735	structural constituent of ribosome
0.36	GO:0042043	neurexin family protein binding
0.34	GO:0004872	receptor activity
0.33	GO:0005096	GTPase activator activity
0.33	GO:0004672	protein kinase activity
0.32	GO:0003676	nucleic acid binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.35	GO:0005840	ribosome
0.35	GO:0009986	cell surface
0.35	GO:0045202	synapse
0.34	GO:0034719	SMN-Sm protein complex
0.34	GO:0005887	integral component of plasma membrane

0.48

GO:0016787

tr|T1G836|T1G836_HELRO
Poly [ADP-ribose] polymerase
Search

0.42	Poly [ADP-ribose] polymerase

0.50	GO:0006998	nuclear envelope organization
0.40	GO:0045071	negative regulation of viral genome replication
0.39	GO:0061014	positive regulation of mRNA catabolic process
0.38	GO:0009615	response to virus
0.37	GO:0016567	protein ubiquitination

0.82	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.39	GO:0045296	cadherin binding
0.37	GO:0004842	ubiquitin-protein transferase activity
0.35	GO:0008270	zinc ion binding
0.35	GO:0016874	ligase activity

0.47	GO:0005635	nuclear envelope
0.37	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.82	EC:2.4.2.30	GO:0003950
0.37	KEGG:R03876	GO:0004842

tr|T1G837|T1G837_HELRO
Uncharacterized protein
Search

0.10	Carboxylic ester hydrolase (Fragment)

0.44	GO:0001941	postsynaptic membrane organization
0.42	GO:0097105	presynaptic membrane assembly
0.41	GO:0043113	receptor clustering
0.40	GO:0007158	neuron cell-cell adhesion
0.40	GO:0099068	postsynapse assembly
0.40	GO:0048488	synaptic vesicle endocytosis
0.39	GO:0050804	modulation of chemical synaptic transmission
0.36	GO:0051124	synaptic growth at neuromuscular junction
0.35	GO:0051589	negative regulation of neurotransmitter transport
0.34	GO:1903531	negative regulation of secretion by cell

0.48	GO:0042043	neurexin family protein binding
0.45	GO:0004104	cholinesterase activity
0.36	GO:0004872	receptor activity
0.36	GO:0097109	neuroligin family protein binding
0.32	GO:0016887	ATPase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.43	GO:0045202	synapse
0.41	GO:0030425	dendrite
0.41	GO:0030424	axon
0.38	GO:0009986	cell surface
0.37	GO:0005886	plasma membrane
0.36	GO:0098820	trans-synaptic protein complex
0.34	GO:0030054	cell junction
0.30	GO:0016021	integral component of membrane

0.45

EC:3.1.1.8

GO:0004104

tr|T1G838|T1G838_HELRO
Uncharacterized protein
Search

tr|T1G839|T1G839_HELRO
Uncharacterized protein
Search

0.10	Proto-oncogene tyrosine-protein kinase FER

0.75	GO:0018108	peptidyl-tyrosine phosphorylation
0.58	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.50	GO:0046777	protein autophosphorylation
0.49	GO:0035556	intracellular signal transduction
0.46	GO:0046664	dorsal closure, amnioserosa morphology change
0.46	GO:0007394	dorsal closure, elongation of leading edge cells
0.44	GO:0030154	cell differentiation
0.43	GO:0051017	actin filament bundle assembly
0.43	GO:0048731	system development
0.42	GO:0120039	plasma membrane bounded cell projection morphogenesis

0.75	GO:0004713	protein tyrosine kinase activity
0.57	GO:0019199	transmembrane receptor protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0005102	receptor binding
0.38	GO:0043560	insulin receptor substrate binding
0.38	GO:0043548	phosphatidylinositol 3-kinase binding
0.34	GO:0005543	phospholipid binding

0.49	GO:0032587	ruffle membrane
0.45	GO:0019898	extrinsic component of membrane
0.44	GO:0005654	nucleoplasm
0.42	GO:0005912	adherens junction
0.41	GO:0009898	cytoplasmic side of plasma membrane
0.35	GO:0005887	integral component of plasma membrane
0.35	GO:0005856	cytoskeleton
0.32	GO:0005737	cytoplasm

0.75

GO:0004713

tr|T1G840|T1G840_HELRO
Uncharacterized protein
Search

ARRDC2

0.77	Arrestin domain-containing protein 3

0.61	GO:0007165	signal transduction
0.36	GO:0071804	cellular potassium ion transport
0.34	GO:0098662	inorganic cation transmembrane transport
0.34	GO:0042391	regulation of membrane potential
0.34	GO:0034765	regulation of ion transmembrane transport

0.36	GO:0098782	mechanosensitived potassium channel activity
0.36	GO:0005227	calcium activated cation channel activity
0.35	GO:0005516	calmodulin binding
0.34	GO:0022843	voltage-gated cation channel activity

0.45	GO:0031410	cytoplasmic vesicle
0.39	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1G841|T1G841_HELRO
Purine nucleoside phosphorylase
Search

0.46	Purine nucleoside phosphorylase I, inosine and guanosine-specific

0.65	GO:0009116	nucleoside metabolic process
0.55	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway
0.51	GO:0019358	nicotinate nucleotide salvage
0.50	GO:1901658	glycosyl compound catabolic process
0.50	GO:0072523	purine-containing compound catabolic process
0.47	GO:0034655	nucleobase-containing compound catabolic process
0.39	GO:0034418	urate biosynthetic process
0.39	GO:0070970	interleukin-2 secretion
0.38	GO:0046638	positive regulation of alpha-beta T cell differentiation
0.38	GO:0042102	positive regulation of T cell proliferation

0.77	GO:0004731	purine-nucleoside phosphorylase activity
0.55	GO:0047724	inosine nucleosidase activity
0.54	GO:0070635	nicotinamide riboside hydrolase activity
0.39	GO:0002060	purine nucleobase binding
0.37	GO:0042301	phosphate ion binding
0.35	GO:0001882	nucleoside binding
0.34	GO:0009032	thymidine phosphorylase activity
0.33	GO:0008144	drug binding

0.36	GO:0005829	cytosol
0.32	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.77

EC:2.4.2.1

GO:0004731

tr|T1G842|T1G842_HELRO
Uncharacterized protein
Search

0.81	Heterogeneous nuclear ribonucleoprotein A/Bb

0.36	GO:0006351	transcription, DNA-templated
0.35	GO:1903506	regulation of nucleic acid-templated transcription
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression
0.35	GO:0035722	interleukin-12-mediated signaling pathway
0.33	GO:0016071	mRNA metabolic process
0.33	GO:0006396	RNA processing

0.56	GO:0003723	RNA binding
0.36	GO:0003697	single-stranded DNA binding
0.36	GO:0003690	double-stranded DNA binding
0.33	GO:0005515	protein binding

0.60	GO:0019013	viral nucleocapsid
0.53	GO:0030529	intracellular ribonucleoprotein complex
0.44	GO:0005654	nucleoplasm
0.36	GO:0070062	extracellular exosome
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1G843|T1G843_HELRO
Uncharacterized protein
Search

0.89	Homeobox protein abdominal-B (inferred by orthology to a D. melanogaster protein)

0.55	GO:2001141	regulation of RNA biosynthetic process
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.48	GO:0007389	pattern specification process
0.48	GO:0009790	embryo development
0.46	GO:0035108	limb morphogenesis
0.46	GO:0048731	system development
0.42	GO:0060429	epithelium development
0.41	GO:0006366	transcription by RNA polymerase II
0.40	GO:0051254	positive regulation of RNA metabolic process

0.62	GO:0043565	sequence-specific DNA binding
0.44	GO:0071837	HMG box domain binding
0.43	GO:0001047	core promoter binding
0.43	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.41	GO:0001012	RNA polymerase II regulatory region DNA binding
0.41	GO:0003682	chromatin binding
0.40	GO:0003690	double-stranded DNA binding
0.33	GO:0051721	protein phosphatase 2A binding

0.61	GO:0005634	nucleus
0.44	GO:0005667	transcription factor complex
0.35	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|T1G844|T1G844_HELRO
Uncharacterized protein
Search

0.10	Dual-specificity phosphatase 10 (Fragment)

0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.67	GO:0000188	inactivation of MAPK activity
0.42	GO:0035970	peptidyl-threonine dephosphorylation
0.38	GO:0001706	endoderm formation
0.35	GO:0045906	negative regulation of vasoconstriction
0.34	GO:0016310	phosphorylation
0.34	GO:0033260	nuclear DNA replication
0.34	GO:0045892	negative regulation of transcription, DNA-templated
0.33	GO:0006313	transposition, DNA-mediated
0.33	GO:0006400	tRNA modification

0.79	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.74	GO:0004725	protein tyrosine phosphatase activity
0.67	GO:0033549	MAP kinase phosphatase activity
0.34	GO:0016301	kinase activity
0.34	GO:0004803	transposase activity
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0003676	nucleic acid binding
0.32	GO:0032555	purine ribonucleotide binding

0.34	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.79

GO:0008138

tr|T1G845|T1G845_HELRO
Uncharacterized protein
Search

0.63	SH2 domain-containing adapter protein F

0.60	GO:0090175	regulation of establishment of planar polarity
0.52	GO:0007165	signal transduction
0.42	GO:0009966	regulation of signal transduction
0.42	GO:0023056	positive regulation of signaling
0.42	GO:0010647	positive regulation of cell communication
0.42	GO:0048584	positive regulation of response to stimulus
0.40	GO:0008283	cell proliferation
0.37	GO:0007018	microtubule-based movement
0.37	GO:0006413	translational initiation
0.37	GO:0023057	negative regulation of signaling

0.45	GO:0005070	SH3/SH2 adaptor activity
0.41	GO:0046872	metal ion binding
0.37	GO:0003777	microtubule motor activity
0.37	GO:0003743	translation initiation factor activity
0.37	GO:0008017	microtubule binding
0.37	GO:0003779	actin binding
0.37	GO:0030971	receptor tyrosine kinase binding
0.36	GO:0030234	enzyme regulator activity
0.36	GO:0016301	kinase activity
0.35	GO:0032559	adenyl ribonucleotide binding

0.40	GO:0005622	intracellular
0.36	GO:0042101	T cell receptor complex
0.36	GO:0045121	membrane raft
0.35	GO:0043234	protein complex
0.35	GO:0043228	non-membrane-bounded organelle
0.34	GO:0044422	organelle part
0.30	GO:0016021	integral component of membrane

0.34

GO:0016773

tr|T1G846|T1G846_HELRO
Uncharacterized protein
Search

0.56	Metabotropic glutamate receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.43	GO:0051966	regulation of synaptic transmission, glutamatergic
0.42	GO:0072553	terminal button organization
0.42	GO:0007614	short-term memory
0.42	GO:0008049	male courtship behavior
0.41	GO:0007616	long-term memory
0.41	GO:0007215	glutamate receptor signaling pathway
0.41	GO:0007528	neuromuscular junction development
0.41	GO:0007612	learning
0.36	GO:0010884	positive regulation of lipid storage

0.72	GO:0004930	G-protein coupled receptor activity
0.42	GO:0016595	glutamate binding
0.41	GO:0008066	glutamate receptor activity
0.41	GO:0015485	cholesterol binding
0.33	GO:0016746	transferase activity, transferring acyl groups
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003676	nucleic acid binding

0.54	GO:0005886	plasma membrane
0.40	GO:0045121	membrane raft
0.33	GO:0043235	receptor complex
0.30	GO:0016021	integral component of membrane

0.33

EC:2.3

GO:0016746

tr|T1G847|T1G847_HELRO
Uncharacterized protein
Search

AHR-1

0.54	Aryl hydrocarbon receptor

0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.55	GO:0006351	transcription, DNA-templated
0.49	GO:0048800	antennal morphogenesis
0.49	GO:0045676	regulation of R7 cell differentiation
0.48	GO:0036011	imaginal disc-derived leg segmentation
0.48	GO:0010092	specification of animal organ identity
0.48	GO:0008049	male courtship behavior
0.47	GO:0048814	regulation of dendrite morphogenesis

0.66	GO:0046983	protein dimerization activity
0.47	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.46	GO:0003677	DNA binding
0.36	GO:0004874	aryl hydrocarbon receptor activity
0.36	GO:0003989	acetyl-CoA carboxylase activity
0.33	GO:0001085	RNA polymerase II transcription factor binding

0.58	GO:0005634	nucleus
0.42	GO:0034751	aryl hydrocarbon receptor complex
0.41	GO:0005667	transcription factor complex
0.36	GO:0005829	cytosol
0.35	GO:0044446	intracellular organelle part
0.30	GO:0044425	membrane part

0.36

EC:6.4.1.2

GO:0003989

tr|T1G848|T1G848_HELRO
Uncharacterized protein
Search

RTCA

0.60	RNA terminal phosphate cyclase domain 1

0.63	GO:0006396	RNA processing
0.36	GO:0048681	negative regulation of axon regeneration
0.32	GO:0042254	ribosome biogenesis
0.32	GO:0006259	DNA metabolic process
0.31	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.31	GO:1903506	regulation of nucleic acid-templated transcription
0.31	GO:0010468	regulation of gene expression

0.85	GO:0003963	RNA-3'-phosphate cyclase activity
0.52	GO:0032559	adenyl ribonucleotide binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0003723	RNA binding
0.32	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters

0.43	GO:0005654	nucleoplasm
0.35	GO:0005737	cytoplasm
0.32	GO:0005730	nucleolus
0.30	GO:0031224	intrinsic component of membrane

0.85

EC:6.5.1.4

GO:0003963

tr|T1G849|T1G849_HELRO
Uncharacterized protein
Search

0.43	GO:0046854	phosphatidylinositol phosphorylation
0.43	GO:0005975	carbohydrate metabolic process
0.43	GO:0008033	tRNA processing
0.39	GO:0022900	electron transport chain

0.49	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.45	GO:0016307	phosphatidylinositol phosphate kinase activity
0.43	GO:0032559	adenyl ribonucleotide binding
0.43	GO:0008144	drug binding
0.43	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0030246	carbohydrate binding
0.41	GO:0046872	metal ion binding
0.40	GO:0020037	heme binding
0.40	GO:0009055	electron transfer activity

0.40	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.49

EC:3.2.1

GO:0004553

tr|T1G850|T1G850_HELRO
Uncharacterized protein
Search

0.83	GO:0016559	peroxisome fission
0.56	GO:0044375	regulation of peroxisome size

0.81	GO:0005779	integral component of peroxisomal membrane
0.43	GO:0043234	protein complex

tr|T1G851|T1G851_HELRO
Uncharacterized protein
Search

0.10	IQ motif and SEC7 domain-containing protein 1

0.81	GO:0032012	regulation of ARF protein signal transduction
0.66	GO:0065009	regulation of molecular function
0.45	GO:0007520	myoblast fusion
0.44	GO:0030036	actin cytoskeleton organization
0.43	GO:0007417	central nervous system development
0.40	GO:0046579	positive regulation of Ras protein signal transduction
0.34	GO:0001745	compound eye morphogenesis

0.82	GO:0005086	ARF guanyl-nucleotide exchange factor activity
0.43	GO:0045296	cadherin binding
0.33	GO:0008289	lipid binding

0.39	GO:0005730	nucleolus
0.38	GO:0000139	Golgi membrane

tr|T1G852|T1G852_HELRO
Uncharacterized protein
Search

RABGAP1

0.88	RAB GTPase activating protein 1 like

0.76	GO:0043547	positive regulation of GTPase activity
0.67	GO:0007049	cell cycle
0.46	GO:0031338	regulation of vesicle fusion
0.41	GO:0032880	regulation of protein localization
0.41	GO:0006886	intracellular protein transport
0.36	GO:1902017	regulation of cilium assembly
0.34	GO:0006897	endocytosis

0.76	GO:0005096	GTPase activator activity
0.54	GO:0017137	Rab GTPase binding
0.34	GO:0015631	tubulin binding
0.33	GO:0008270	zinc ion binding
0.32	GO:0003677	DNA binding

0.45	GO:0005829	cytosol
0.43	GO:0005769	early endosome
0.42	GO:0005929	cilium
0.41	GO:0005794	Golgi apparatus
0.38	GO:0005634	nucleus
0.36	GO:0005815	microtubule organizing center
0.34	GO:0005875	microtubule associated complex
0.30	GO:0031224	intrinsic component of membrane

tr|T1G853|T1G853_HELRO
Uncharacterized protein
Search

PWP2

0.74	Periodic tryptophan protein 2

0.74	GO:0000028	ribosomal small subunit assembly
0.67	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.57	GO:0055123	digestive system development
0.44	GO:0000920	cell separation after cytokinesis
0.44	GO:0000479	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.43	GO:0030010	establishment of cell polarity
0.43	GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.43	GO:0000967	rRNA 5'-end processing

0.68	GO:0030515	snoRNA binding
0.30	GO:0003824	catalytic activity

0.72	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome
0.66	GO:0032040	small-subunit processome
0.38	GO:0005654	nucleoplasm
0.36	GO:0019013	viral nucleocapsid
0.35	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1G854|T1G854_HELRO
Uncharacterized protein
Search

RSPRY1

0.96	Novel protein containing SPRY domain-containing SOCS box protein SSB-3

0.36	GO:0010467	gene expression
0.36	GO:0043043	peptide biosynthetic process
0.35	GO:0044267	cellular protein metabolic process
0.35	GO:0009059	macromolecule biosynthetic process
0.34	GO:0016070	RNA metabolic process

0.53	GO:0046872	metal ion binding
0.38	GO:0008452	RNA ligase activity
0.37	GO:0003735	structural constituent of ribosome

0.43	GO:0005576	extracellular region
0.37	GO:0005581	collagen trimer
0.36	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

0.38

EC:6.5.1

GO:0008452

tr|T1G855|T1G855_HELRO
Uncharacterized protein
Search

0.63	Eukaryotic translation elongation factor 1 epsilon-1

0.70

GO:0006414

translational elongation

0.71

GO:0003746

translation elongation factor activity

tr|T1G856|T1G856_HELRO
Uncharacterized protein
Search

0.43	GO:0000122	negative regulation of transcription by RNA polymerase II
0.39	GO:0007424	open tracheal system development
0.39	GO:0002165	instar larval or pupal development
0.38	GO:0071390	cellular response to ecdysone
0.37	GO:0048076	regulation of compound eye pigmentation
0.37	GO:0035146	tube fusion
0.37	GO:0042332	gravitaxis
0.37	GO:0032876	negative regulation of DNA endoreduplication
0.37	GO:0036335	intestinal stem cell homeostasis
0.37	GO:0035215	genital disc development

0.51	GO:0003676	nucleic acid binding
0.42	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.41	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.35	GO:0005507	copper ion binding
0.34	GO:0008270	zinc ion binding

0.38	GO:0005634	nucleus
0.37	GO:0005667	transcription factor complex

tr|T1G857|T1G857_HELRO
Uncharacterized protein
Search

0.53	GO:0055114	oxidation-reduction process
0.42	GO:0019369	arachidonic acid metabolic process
0.36	GO:0007565	female pregnancy
0.35	GO:0006587	serotonin biosynthetic process from tryptophan
0.35	GO:0042416	dopamine biosynthetic process
0.34	GO:0006704	glucocorticoid biosynthetic process
0.34	GO:0042448	progesterone metabolic process
0.34	GO:0042221	response to chemical

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.66	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.34	GO:0019825	oxygen binding
0.34	GO:0047442	17-alpha-hydroxyprogesterone aldolase activity

0.38	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0031090	organelle membrane
0.34	GO:0043025	neuronal cell body
0.34	GO:0030424	axon
0.32	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.68

EC:1.14

GO:0016705

tr|T1G858|T1G858_HELRO
Uncharacterized protein
Search

UBL3

0.83	ubiquitin-like protein 3

0.66	GO:0070062	extracellular exosome
0.56	GO:0005886	plasma membrane
0.43	GO:0005622	intracellular

tr|T1G859|T1G859_HELRO
Uncharacterized protein
Search

0.85	GO:0008053	mitochondrial fusion
0.48	GO:0060348	bone development

0.46	GO:0042803	protein homodimerization activity
0.46	GO:0046982	protein heterodimerization activity

0.43	GO:0005887	integral component of plasma membrane
0.38	GO:0005741	mitochondrial outer membrane

tr|T1G860|T1G860_HELRO
Uncharacterized protein
Search

POLR2D

0.89	RNA polymerase II subunit D

0.58	GO:0006351	transcription, DNA-templated
0.48	GO:0031990	mRNA export from nucleus in response to heat stress
0.47	GO:0034402	recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex
0.46	GO:0045948	positive regulation of translational initiation
0.45	GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
0.35	GO:0035079	polytene chromosome puffing
0.35	GO:0035019	somatic stem cell population maintenance
0.34	GO:0060964	regulation of gene silencing by miRNA
0.34	GO:0008543	fibroblast growth factor receptor signaling pathway
0.34	GO:0016073	snRNA metabolic process

0.70	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.53	GO:1901265	nucleoside phosphate binding
0.51	GO:0036094	small molecule binding
0.46	GO:0031369	translation initiation factor binding
0.45	GO:0003727	single-stranded RNA binding
0.43	GO:0003697	single-stranded DNA binding
0.35	GO:0008270	zinc ion binding

0.51	GO:0005665	DNA-directed RNA polymerase II, core complex
0.49	GO:0016607	nuclear speck
0.45	GO:0000932	P-body
0.45	GO:0005829	cytosol
0.35	GO:0005701	polytene chromosome chromocenter
0.34	GO:0005705	polytene chromosome interband

0.70

GO:0003899

tr|T1G861|T1G861_HELRO
Uncharacterized protein
Search

0.40	muscleblind-like protein 1 isoform X7

0.54

GO:0046872

metal ion binding

tr|T1G862|T1G862_HELRO
Uncharacterized protein
Search

tr|T1G863|T1G863_HELRO
Uncharacterized protein
Search

0.76	Basic helix-loop-helix transcription factor scleraxis

0.52	GO:0007498	mesoderm development
0.52	GO:0061053	somite development
0.52	GO:0048705	skeletal system morphogenesis
0.51	GO:0060485	mesenchyme development
0.50	GO:0007517	muscle organ development
0.50	GO:0048729	tissue morphogenesis
0.50	GO:0043009	chordate embryonic development
0.49	GO:0003016	respiratory system process
0.49	GO:0060231	mesenchymal to epithelial transition
0.49	GO:0050884	neuromuscular process controlling posture

0.68	GO:0046983	protein dimerization activity
0.51	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.50	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.46	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.45	GO:0043425	bHLH transcription factor binding
0.43	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.43	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.38	GO:0003729	mRNA binding
0.34	GO:0005337	nucleoside transmembrane transporter activity
0.33	GO:0008270	zinc ion binding

0.49	GO:0005667	transcription factor complex
0.44	GO:0005634	nucleus
0.39	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

tr|T1G864|T1G864_HELRO
Uncharacterized protein
Search

0.68	Ubiquinone biosynthesis protein COQ9, mitochondrial

0.75	GO:0006744	ubiquinone biosynthetic process
0.33	GO:0055114	oxidation-reduction process

0.36	GO:0031418	L-ascorbic acid binding
0.35	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.34	GO:0005506	iron ion binding

0.30

GO:0031224

intrinsic component of membrane

0.35

EC:1.14

GO:0016705

tr|T1G865|T1G865_HELRO
Uncharacterized protein
Search

0.48	sex peptide receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.35	GO:0006468	protein phosphorylation

0.77	GO:0008528	G-protein coupled peptide receptor activity
0.39	GO:0050254	rhodopsin kinase activity

0.30

GO:0044425

membrane part

0.39

EC:2.7.11.14

GO:0050254

tr|T1G866|T1G866_HELRO
Uncharacterized protein
Search

0.54	Ribosomal protein L37

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process

0.66	GO:0019843	rRNA binding
0.64	GO:0003735	structural constituent of ribosome
0.54	GO:0046872	metal ion binding

0.61

GO:0005840

ribosome

tr|T1G868|T1G868_HELRO
Uncharacterized protein
Search

0.34	Guanylate cyclase

0.81	GO:0006182	cGMP biosynthetic process
0.63	GO:0006468	protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.43	GO:0007168	receptor guanylyl cyclase signaling pathway
0.42	GO:1900194	negative regulation of oocyte maturation
0.42	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus
0.41	GO:0051447	negative regulation of meiotic cell cycle
0.41	GO:0032501	multicellular organismal process
0.39	GO:0048856	anatomical structure development
0.38	GO:1904640	response to methionine

0.82	GO:0004383	guanylate cyclase activity
0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0016941	natriuretic peptide receptor activity
0.44	GO:0004016	adenylate cyclase activity
0.41	GO:0017046	peptide hormone binding
0.39	GO:0042802	identical protein binding
0.34	GO:0005089	Rho guanyl-nucleotide exchange factor activity

0.46	GO:0008074	guanylate cyclase complex, soluble
0.39	GO:0005886	plasma membrane
0.35	GO:0043204	perikaryon
0.34	GO:0030425	dendrite
0.34	GO:0030424	axon
0.30	GO:0016021	integral component of membrane

0.82

GO:0004383

tr|T1G869|T1G869_HELRO
Uncharacterized protein
Search

0.59	Zinc finger MYM-type protein 1

0.37	GO:0006357	regulation of transcription by RNA polymerase II
0.35	GO:0007275	multicellular organism development
0.34	GO:0006796	phosphate-containing compound metabolic process
0.33	GO:0008299	isoprenoid biosynthetic process
0.33	GO:0072527	pyrimidine-containing compound metabolic process
0.33	GO:0006313	transposition, DNA-mediated
0.32	GO:0055086	nucleobase-containing small molecule metabolic process
0.32	GO:0019637	organophosphate metabolic process
0.32	GO:1901135	carbohydrate derivative metabolic process

0.68	GO:0046983	protein dimerization activity
0.37	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.34	GO:0003677	DNA binding
0.34	GO:0016301	kinase activity
0.34	GO:0019901	protein kinase binding
0.34	GO:0004170	dUTP diphosphatase activity
0.33	GO:0008270	zinc ion binding
0.33	GO:0004803	transposase activity

0.36	GO:0005654	nucleoplasm
0.33	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.34	EC:3.6.1.23	GO:0004170
0.34	KEGG:R02100	GO:0004170

tr|T1G870|T1G870_HELRO
Uncharacterized protein
Search

0.73	GO:0007018	microtubule-based movement
0.47	GO:1903028	positive regulation of opsonization
0.46	GO:0090164	asymmetric Golgi ribbon formation
0.46	GO:0031032	actomyosin structure organization
0.44	GO:0043030	regulation of macrophage activation
0.43	GO:0050714	positive regulation of protein secretion
0.43	GO:0048194	Golgi vesicle budding
0.43	GO:0006259	DNA metabolic process
0.42	GO:0043066	negative regulation of apoptotic process
0.42	GO:0016477	cell migration

0.75	GO:0051015	actin filament binding
0.73	GO:0008017	microtubule binding
0.73	GO:0003777	microtubule motor activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0008094	DNA-dependent ATPase activity
0.41	GO:0003677	DNA binding
0.33	GO:0003723	RNA binding
0.32	GO:0046872	metal ion binding

0.75	GO:0016459	myosin complex
0.44	GO:0042641	actomyosin
0.43	GO:0005802	trans-Golgi network
0.41	GO:0000139	Golgi membrane
0.35	GO:0005903	brush border
0.35	GO:0045335	phagocytic vesicle
0.35	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.34	GO:0005922	connexin complex
0.33	GO:0009986	cell surface
0.30	GO:0016021	integral component of membrane

tr|T1G871|T1G871_HELRO
Uncharacterized protein
Search

0.80	Programmed cell death

0.63	GO:1904761	negative regulation of myofibroblast differentiation
0.63	GO:1905064	negative regulation of vascular smooth muscle cell differentiation
0.63	GO:1905461	positive regulation of vascular associated smooth muscle cell apoptotic process
0.62	GO:1900016	negative regulation of cytokine production involved in inflammatory response
0.61	GO:2000353	positive regulation of endothelial cell apoptotic process
0.61	GO:1904706	negative regulation of vascular smooth muscle cell proliferation
0.60	GO:0032502	developmental process
0.59	GO:1901224	positive regulation of NIK/NF-kappaB signaling
0.58	GO:2000738	positive regulation of stem cell differentiation
0.58	GO:0030509	BMP signaling pathway

0.43	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity
0.37	GO:0003723	RNA binding

0.52	GO:0005829	cytosol
0.48	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.43

EC:2.4.1.135

GO:0015018

tr|T1G872|T1G872_HELRO
Uncharacterized protein
Search

tr|T1G873|T1G873_HELRO
Uncharacterized protein
Search

0.72	GO:0007018	microtubule-based movement
0.44	GO:0048739	cardiac muscle fiber development
0.42	GO:0001570	vasculogenesis
0.40	GO:0042157	lipoprotein metabolic process
0.39	GO:0006869	lipid transport

0.73	GO:0003779	actin binding
0.72	GO:0003777	microtubule motor activity
0.72	GO:0008017	microtubule binding
0.66	GO:0032403	protein complex binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0008289	lipid binding

0.75	GO:0016459	myosin complex
0.42	GO:0031941	filamentous actin
0.42	GO:0030018	Z disc
0.38	GO:0005576	extracellular region
0.30	GO:0016020	membrane

tr|T1G874|T1G874_HELRO
Uncharacterized protein
Search

0.10	Homeotic deformed protein

0.63	GO:0007275	multicellular organism development
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.39	GO:1902339	positive regulation of apoptotic process involved in morphogenesis
0.39	GO:0060323	head morphogenesis
0.37	GO:0051254	positive regulation of RNA metabolic process
0.37	GO:0010557	positive regulation of macromolecule biosynthetic process
0.37	GO:0031328	positive regulation of cellular biosynthetic process
0.37	GO:0051253	negative regulation of RNA metabolic process

0.64	GO:0043565	sequence-specific DNA binding
0.56	GO:0003700	DNA binding transcription factor activity
0.38	GO:0033613	activating transcription factor binding
0.38	GO:0035326	enhancer binding
0.38	GO:0001012	RNA polymerase II regulatory region DNA binding
0.37	GO:0003690	double-stranded DNA binding
0.33	GO:0004000	adenosine deaminase activity
0.32	GO:0018024	histone-lysine N-methyltransferase activity
0.32	GO:0004813	alanine-tRNA ligase activity
0.32	GO:0008270	zinc ion binding

0.61	GO:0005634	nucleus
0.36	GO:0030054	cell junction
0.36	GO:0043233	organelle lumen
0.34	GO:0044446	intracellular organelle part
0.32	GO:0012505	endomembrane system
0.32	GO:0031090	organelle membrane
0.32	GO:0031975	envelope
0.32	GO:0005694	chromosome
0.31	GO:0005739	mitochondrion
0.30	GO:0044425	membrane part

0.33

GO:0004000

tr|T1G875|T1G875_HELRO
Uncharacterized protein
Search

0.39	GO:0007050	cell cycle arrest
0.38	GO:0036211	protein modification process
0.36	GO:0030308	negative regulation of cell growth
0.36	GO:0044267	cellular protein metabolic process
0.36	GO:0006796	phosphate-containing compound metabolic process
0.34	GO:0022900	electron transport chain
0.34	GO:0006508	proteolysis

0.37	GO:0140096	catalytic activity, acting on a protein
0.37	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.36	GO:0016301	kinase activity
0.36	GO:0016681	oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor
0.36	GO:0016791	phosphatase activity
0.36	GO:0051537	2 iron, 2 sulfur cluster binding
0.35	GO:0008289	lipid binding
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.42	GO:0005654	nucleoplasm
0.37	GO:0005783	endoplasmic reticulum
0.30	GO:0031224	intrinsic component of membrane

0.37

GO:0016773

tr|T1G876|T1G876_HELRO
Uncharacterized protein
Search

0.67	factor VIII intron 22 protein-like

0.49	GO:0006357	regulation of transcription by RNA polymerase II
0.48	GO:0006468	protein phosphorylation

0.53	GO:0001104	RNA polymerase II transcription cofactor activity
0.48	GO:0004672	protein kinase activity
0.43	GO:0032559	adenyl ribonucleotide binding
0.43	GO:0008144	drug binding
0.43	GO:0035639	purine ribonucleoside triphosphate binding

0.52	GO:0016592	mediator complex
0.30	GO:0016020	membrane

tr|T1G877|T1G877_HELRO
Uncharacterized protein
Search

CISD3

0.41	Cdgsh iron sulfur domain-containing protein mitochondrial

0.37	GO:0006508	proteolysis
0.36	GO:0006537	glutamate biosynthetic process
0.34	GO:0006379	mRNA cleavage
0.34	GO:0055114	oxidation-reduction process
0.33	GO:0009190	cyclic nucleotide biosynthetic process
0.33	GO:0006351	transcription, DNA-templated
0.33	GO:0035556	intracellular signal transduction
0.32	GO:0006091	generation of precursor metabolites and energy

0.71	GO:0051537	2 iron, 2 sulfur cluster binding
0.39	GO:0008238	exopeptidase activity
0.37	GO:0015930	glutamate synthase activity
0.35	GO:0016639	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
0.34	GO:0008270	zinc ion binding
0.33	GO:0008237	metallopeptidase activity
0.33	GO:0016849	phosphorus-oxygen lyase activity
0.33	GO:0009055	electron transfer activity
0.32	GO:0003676	nucleic acid binding

0.56	GO:0043231	intracellular membrane-bounded organelle
0.32	GO:0044444	cytoplasmic part
0.30	GO:0016020	membrane

0.37

EC:1.4

GO:0015930

tr|T1G878|T1G878_HELRO
Uncharacterized protein
Search

0.53	Transcriptional enhancer factor

0.81	GO:0035329	hippo signaling
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0006351	transcription, DNA-templated
0.52	GO:1902680	positive regulation of RNA biosynthetic process
0.48	GO:0048368	lateral mesoderm development
0.47	GO:0048339	paraxial mesoderm development
0.47	GO:0030903	notochord development
0.47	GO:0071300	cellular response to retinoic acid

0.61	GO:0003700	DNA binding transcription factor activity
0.51	GO:0003677	DNA binding
0.49	GO:0001223	transcription coactivator binding
0.48	GO:0097718	disordered domain specific binding
0.47	GO:0001134	transcription factor activity, transcription factor recruiting
0.44	GO:0001085	RNA polymerase II transcription factor binding
0.44	GO:0046982	protein heterodimerization activity
0.42	GO:0001067	regulatory region nucleic acid binding
0.33	GO:0004252	serine-type endopeptidase activity

0.56	GO:0005634	nucleus
0.46	GO:0005667	transcription factor complex
0.43	GO:0005829	cytosol
0.42	GO:0043233	organelle lumen
0.39	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0004252

tr|T1G879|T1G879_HELRO
Uncharacterized protein
Search

tr|T1G880|T1G880_HELRO
Uncharacterized protein
Search

0.53	Fructose-bisphosphate aldolase

0.71	GO:0006757	ATP generation from ADP
0.69	GO:0006090	pyruvate metabolic process
0.68	GO:0016052	carbohydrate catabolic process
0.67	GO:0019362	pyridine nucleotide metabolic process
0.37	GO:0006000	fructose metabolic process
0.36	GO:0030388	fructose 1,6-bisphosphate metabolic process
0.35	GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly
0.35	GO:0032781	positive regulation of ATPase activity
0.34	GO:0007498	mesoderm development
0.34	GO:0042593	glucose homeostasis

0.79	GO:0004332	fructose-bisphosphate aldolase activity
0.37	GO:0070061	fructose binding
0.36	GO:0061609	fructose-1-phosphate aldolase activity
0.35	GO:0051117	ATPase binding
0.35	GO:0008092	cytoskeletal protein binding
0.34	GO:0042802	identical protein binding
0.33	GO:0045296	cadherin binding

0.36	GO:0034451	centriolar satellite
0.34	GO:0005829	cytosol
0.34	GO:0031430	M band
0.34	GO:0030018	Z disc
0.34	GO:0005615	extracellular space
0.34	GO:0045335	phagocytic vesicle
0.33	GO:0061827	sperm head
0.33	GO:1903561	extracellular vesicle
0.33	GO:0015629	actin cytoskeleton
0.30	GO:0016020	membrane

0.79

EC:4.1.2.13

GO:0004332

tr|T1G881|T1G881_HELRO
Uncharacterized protein
Search

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.45	GO:0007399	nervous system development
0.44	GO:0007423	sensory organ development
0.43	GO:0002009	morphogenesis of an epithelium
0.43	GO:0030154	cell differentiation
0.43	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.42	GO:0007164	establishment of tissue polarity
0.42	GO:0007424	open tracheal system development
0.42	GO:0007166	cell surface receptor signaling pathway
0.42	GO:0007389	pattern specification process

0.70	GO:0005509	calcium ion binding
0.42	GO:0004930	G-protein coupled receptor activity
0.39	GO:0005057	signal transducer activity, downstream of receptor
0.37	GO:0050839	cell adhesion molecule binding
0.35	GO:0032403	protein complex binding
0.34	GO:0017022	myosin binding
0.33	GO:0004664	prephenate dehydratase activity
0.33	GO:0004725	protein tyrosine phosphatase activity
0.33	GO:0042802	identical protein binding

0.56	GO:0005886	plasma membrane
0.40	GO:0098858	actin-based cell projection
0.40	GO:0030054	cell junction
0.39	GO:0098862	cluster of actin-based cell projections
0.38	GO:0043005	neuron projection
0.38	GO:0045177	apical part of cell
0.36	GO:0031254	cell trailing edge
0.36	GO:0045178	basal part of cell
0.35	GO:0120038	plasma membrane bounded cell projection part
0.35	GO:0044422	organelle part

0.33

EC:4.2.1.51

GO:0004664

tr|T1G882|T1G882_HELRO
Uncharacterized protein
Search

RSBN1

0.82	Round spermatid basic protein 1

0.36	GO:0035335	peptidyl-tyrosine dephosphorylation
0.35	GO:0016569	covalent chromatin modification
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression
0.33	GO:0055114	oxidation-reduction process
0.32	GO:0006351	transcription, DNA-templated
0.32	GO:0006886	intracellular protein transport
0.32	GO:0016192	vesicle-mediated transport

0.36	GO:0004725	protein tyrosine phosphatase activity
0.35	GO:0051213	dioxygenase activity
0.33	GO:0003677	DNA binding
0.33	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding
0.33	GO:0003700	DNA binding transcription factor activity

0.61	GO:0005634	nucleus
0.33	GO:0030131	clathrin adaptor complex
0.30	GO:0016021	integral component of membrane

0.36

GO:0004725

tr|T1G883|T1G883_HELRO
Uncharacterized protein
Search

HMG-1.2

0.92	High mobility group protein 1.2

0.55

GO:0003677

DNA binding

0.61	GO:0005634	nucleus
0.30	GO:0044425	membrane part

tr|T1G884|T1G884_HELRO
Uncharacterized protein
Search

0.58	GO:0006351	transcription, DNA-templated
0.34	GO:0031048	chromatin silencing by small RNA
0.33	GO:0001172	transcription, RNA-templated

0.70	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.65	GO:0001882	nucleoside binding
0.55	GO:0003677	DNA binding
0.33	GO:0003968	RNA-directed 5'-3' RNA polymerase activity
0.32	GO:0003723	RNA binding
0.32	GO:0046872	metal ion binding

0.41	GO:0005665	DNA-directed RNA polymerase II, core complex
0.34	GO:0031618	nuclear pericentric heterochromatin
0.34	GO:0010494	cytoplasmic stress granule
0.30	GO:0031224	intrinsic component of membrane

0.70

GO:0003899

tr|T1G885|T1G885_HELRO
Uncharacterized protein
Search

0.53	High mobility group protein B3

0.57	GO:0032392	DNA geometric change
0.52	GO:0045578	negative regulation of B cell differentiation
0.49	GO:0045638	negative regulation of myeloid cell differentiation
0.38	GO:0045087	innate immune response
0.35	GO:0006351	transcription, DNA-templated
0.35	GO:2001141	regulation of RNA biosynthetic process
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression
0.34	GO:0006310	DNA recombination
0.33	GO:0007275	multicellular organism development

0.68	GO:0000400	four-way junction DNA binding
0.67	GO:0008301	DNA binding, bending
0.40	GO:0003723	RNA binding
0.36	GO:0003690	double-stranded DNA binding
0.34	GO:0005515	protein binding
0.33	GO:0003697	single-stranded DNA binding
0.32	GO:0016887	ATPase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005634	nucleus
0.36	GO:0005694	chromosome
0.34	GO:0032300	mismatch repair complex
0.34	GO:0005737	cytoplasm
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.32	GO:0044446	intracellular organelle part

0.32

GO:0016887

tr|T1G886|T1G886_HELRO
Uncharacterized protein
Search

tr|T1G887|T1G887_HELRO
Uncharacterized protein
Search

0.45	Eukaryotic translation initiation factor 3 subunit J

0.55

GO:0055085

transmembrane transport

0.44

GO:0005215

transporter activity

0.40

GO:0005887

integral component of plasma membrane

tr|T1G888|T1G888_HELRO
Uncharacterized protein
Search

0.30

GO:0044425

membrane part

tr|T1G889|T1G889_HELRO
Uncharacterized protein
Search

0.73	Cell division cycle 14Ab

0.75	GO:0035335	peptidyl-tyrosine dephosphorylation
0.58	GO:0060271	cilium assembly
0.54	GO:0051256	mitotic spindle midzone assembly
0.53	GO:0071850	mitotic cell cycle arrest
0.52	GO:1901987	regulation of cell cycle phase transition
0.50	GO:0007088	regulation of mitotic nuclear division
0.47	GO:0072422	signal transduction involved in DNA damage checkpoint
0.47	GO:0031572	G2 DNA damage checkpoint
0.46	GO:0051301	cell division
0.46	GO:1904668	positive regulation of ubiquitin protein ligase activity

0.79	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.75	GO:0004725	protein tyrosine phosphatase activity
0.51	GO:0004722	protein serine/threonine phosphatase activity

0.57	GO:0005819	spindle
0.52	GO:0005813	centrosome
0.52	GO:0005730	nucleolus
0.49	GO:0000793	condensed chromosome
0.43	GO:0005654	nucleoplasm
0.38	GO:0036064	ciliary basal body
0.38	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.79

GO:0008138

tr|T1G890|T1G890_HELRO
Uncharacterized protein
Search

0.11	Homeobox-leucine zipper protein HDG12 (Fragment)

0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression
0.34	GO:0097659	nucleic acid-templated transcription
0.33	GO:0010467	gene expression
0.33	GO:0034645	cellular macromolecule biosynthetic process

0.71	GO:0008289	lipid binding
0.65	GO:0043565	sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.30	GO:0044425	membrane part

tr|T1G891|T1G891_HELRO
Uncharacterized protein
Search

tr|T1G892|T1G892_HELRO
Uncharacterized protein
Search

tr|T1G893|T1G893_HELRO
Uncharacterized protein
Search

0.83	GO:1904247	positive regulation of polynucleotide adenylyltransferase activity
0.44	GO:0042981	regulation of apoptotic process
0.44	GO:0006915	apoptotic process
0.43	GO:0071222	cellular response to lipopolysaccharide
0.43	GO:0016973	poly(A)+ mRNA export from nucleus
0.42	GO:0000165	MAPK cascade
0.41	GO:0043069	negative regulation of programmed cell death
0.36	GO:0038034	signal transduction in absence of ligand
0.36	GO:0031124	mRNA 3'-end processing
0.35	GO:1902532	negative regulation of intracellular signal transduction

0.59	GO:0003723	RNA binding
0.42	GO:0097718	disordered domain specific binding
0.42	GO:0070063	RNA polymerase binding
0.40	GO:0042802	identical protein binding
0.40	GO:0046982	protein heterodimerization activity
0.36	GO:0043621	protein self-association
0.36	GO:0003714	transcription corepressor activity
0.34	GO:0008484	sulfuric ester hydrolase activity
0.34	GO:0003700	DNA binding transcription factor activity
0.34	GO:0004820	glycine-tRNA ligase activity

0.45	GO:0042405	nuclear inclusion body
0.43	GO:0097136	Bcl-2 family protein complex
0.38	GO:0030529	intracellular ribonucleoprotein complex
0.37	GO:0016607	nuclear speck
0.35	GO:0005741	mitochondrial outer membrane

0.34

EC:3.1.6

GO:0008484

tr|T1G894|T1G894_HELRO
Uncharacterized protein
Search

tr|T1G895|T1G895_HELRO
Uncharacterized protein
Search

0.40	Histone-lysine N-methyltransferase

0.78	GO:0034968	histone lysine methylation
0.49	GO:0018026	peptidyl-lysine monomethylation
0.45	GO:0043516	regulation of DNA damage response, signal transduction by p53 class mediator
0.43	GO:0000122	negative regulation of transcription by RNA polymerase II
0.41	GO:0000077	DNA damage checkpoint
0.40	GO:0030261	chromosome condensation
0.36	GO:0051301	cell division
0.36	GO:0007049	cell cycle
0.35	GO:0006351	transcription, DNA-templated
0.34	GO:0035067	negative regulation of histone acetylation

0.79	GO:0018024	histone-lysine N-methyltransferase activity
0.45	GO:0002039	p53 binding
0.44	GO:0003714	transcription corepressor activity

0.42	GO:0005700	polytene chromosome
0.40	GO:0005829	cytosol
0.40	GO:0005634	nucleus
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.79

EC:2.1.1.43

GO:0018024

tr|T1G896|T1G896_HELRO
tRNA (guanine-N(7)-)-methyltransferase
Search

METTL1

0.55	tRNA (guanine-N(7)-)-methyltransferase A

0.79	GO:0106004	tRNA (guanine-N7)-methylation
0.34	GO:0007076	mitotic chromosome condensation
0.33	GO:0055114	oxidation-reduction process
0.32	GO:0005975	carbohydrate metabolic process

0.80	GO:0008176	tRNA (guanine-N7-)-methyltransferase activity
0.69	GO:0000049	tRNA binding
0.34	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.34	GO:0020037	heme binding
0.34	GO:0005506	iron ion binding
0.34	GO:0008061	chitin binding
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.45	GO:0043527	tRNA methyltransferase complex
0.44	GO:0005829	cytosol
0.44	GO:0043233	organelle lumen
0.41	GO:0043232	intracellular non-membrane-bounded organelle
0.40	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.80

EC:2.1.1.33

GO:0008176

tr|T1G897|T1G897_HELRO
Uncharacterized protein
Search

CHDH

0.49	Choline dehydrogenase, mitochondrial

0.69	GO:0019285	glycine betaine biosynthetic process from choline
0.53	GO:0055114	oxidation-reduction process
0.36	GO:0002191	cap-dependent translational initiation
0.35	GO:0001731	formation of translation preinitiation complex
0.35	GO:0006446	regulation of translational initiation
0.33	GO:0007186	G-protein coupled receptor signaling pathway

0.71	GO:0008812	choline dehydrogenase activity
0.66	GO:0050660	flavin adenine dinucleotide binding
0.36	GO:0098808	mRNA cap binding
0.35	GO:0008802	betaine-aldehyde dehydrogenase activity
0.35	GO:0003743	translation initiation factor activity
0.33	GO:0004930	G-protein coupled receptor activity
0.33	GO:0016787	hydrolase activity

0.38	GO:0031966	mitochondrial membrane
0.38	GO:0019866	organelle inner membrane
0.36	GO:0005852	eukaryotic translation initiation factor 3 complex
0.35	GO:0016282	eukaryotic 43S preinitiation complex
0.35	GO:0033290	eukaryotic 48S preinitiation complex
0.30	GO:0031224	intrinsic component of membrane

0.71	EC:1.1.99.1	GO:0008812
0.71	KEGG:R01025	GO:0008812

tr|T1G898|T1G898_HELRO
Uncharacterized protein
Search

CHDH

0.48	Choline dehydrogenase, mitochondrial

0.69	GO:0019285	glycine betaine biosynthetic process from choline
0.53	GO:0055114	oxidation-reduction process
0.36	GO:0002191	cap-dependent translational initiation
0.35	GO:0001731	formation of translation preinitiation complex
0.35	GO:0006446	regulation of translational initiation
0.33	GO:0007186	G-protein coupled receptor signaling pathway

0.71	GO:0008812	choline dehydrogenase activity
0.66	GO:0050660	flavin adenine dinucleotide binding
0.36	GO:0098808	mRNA cap binding
0.35	GO:0008802	betaine-aldehyde dehydrogenase activity
0.35	GO:0003743	translation initiation factor activity
0.33	GO:0004930	G-protein coupled receptor activity
0.33	GO:0016787	hydrolase activity

0.38	GO:0031966	mitochondrial membrane
0.38	GO:0019866	organelle inner membrane
0.36	GO:0005852	eukaryotic translation initiation factor 3 complex
0.35	GO:0016282	eukaryotic 43S preinitiation complex
0.35	GO:0033290	eukaryotic 48S preinitiation complex
0.30	GO:0031224	intrinsic component of membrane

0.71	EC:1.1.99.1	GO:0008812
0.71	KEGG:R01025	GO:0008812

tr|T1G899|T1G899_HELRO
Uncharacterized protein
Search

tr|T1G8A0|T1G8A0_HELRO
Uncharacterized protein
Search

tr|T1G8A1|T1G8A1_HELRO
Uncharacterized protein
Search

tr|T1G8A2|T1G8A2_HELRO
Uncharacterized protein
Search

0.39	GO:1990954	establishment of protein localization to meiotic spindle pole body
0.37	GO:0090307	mitotic spindle assembly
0.36	GO:0006468	protein phosphorylation

0.70	GO:0005509	calcium ion binding
0.36	GO:0016301	kinase activity
0.35	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.35	GO:0140096	catalytic activity, acting on a protein
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.38	GO:0035840	old growing cell tip
0.38	GO:0035841	new growing cell tip
0.38	GO:0035974	meiotic spindle pole body
0.38	GO:0000935	division septum
0.37	GO:0044732	mitotic spindle pole body
0.37	GO:0043332	mating projection tip
0.30	GO:0031224	intrinsic component of membrane

0.35

GO:0016773

tr|T1G8A3|T1G8A3_HELRO
Uncharacterized protein
Search

0.10	AN1-type zinc finger protein 6-like Protein

0.53	GO:0010761	fibroblast migration
0.53	GO:0003016	respiratory system process
0.53	GO:0048745	smooth muscle tissue development
0.52	GO:0048008	platelet-derived growth factor receptor signaling pathway
0.52	GO:0060324	face development
0.50	GO:0048705	skeletal system morphogenesis
0.49	GO:0001944	vasculature development
0.48	GO:0001701	in utero embryonic development

0.63	GO:0008270	zinc ion binding
0.54	GO:0003677	DNA binding
0.33	GO:0005515	protein binding

0.33

GO:0005737

cytoplasm

tr|T1G8A4|T1G8A4_HELRO
Uncharacterized protein
Search

0.70	GO:0016525	negative regulation of angiogenesis
0.60	GO:0007186	G-protein coupled receptor signaling pathway
0.59	GO:0007166	cell surface receptor signaling pathway
0.51	GO:0061743	motor learning
0.51	GO:0099558	maintenance of synapse structure
0.51	GO:0007520	myoblast fusion
0.49	GO:0016322	neuron remodeling
0.49	GO:0051965	positive regulation of synapse assembly
0.48	GO:0048814	regulation of dendrite morphogenesis
0.47	GO:0051336	regulation of hydrolase activity

0.61	GO:0004930	G-protein coupled receptor activity
0.50	GO:0005509	calcium ion binding
0.47	GO:0030234	enzyme regulator activity
0.37	GO:0008237	metallopeptidase activity
0.35	GO:0038191	neuropilin binding
0.34	GO:0004175	endopeptidase activity
0.33	GO:0008270	zinc ion binding

0.50	GO:0043083	synaptic cleft
0.46	GO:0098794	postsynapse
0.45	GO:0005578	proteinaceous extracellular matrix
0.42	GO:0044420	extracellular matrix component
0.41	GO:0071944	cell periphery
0.40	GO:0099568	cytoplasmic region
0.40	GO:0030054	cell junction
0.35	GO:0005615	extracellular space
0.30	GO:0016020	membrane

tr|T1G8A5|T1G8A5_HELRO
Uncharacterized protein
Search

tr|T1G8A6|T1G8A6_HELRO
Uncharacterized protein
Search

0.35	40S ribosomal protein S7

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.35	GO:0042274	ribosomal small subunit biogenesis
0.35	GO:0016072	rRNA metabolic process
0.34	GO:0030097	hemopoiesis
0.34	GO:0043009	chordate embryonic development
0.33	GO:1902600	hydrogen ion transmembrane transport
0.33	GO:0051726	regulation of cell cycle

0.64	GO:0003735	structural constituent of ribosome
0.33	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.33	GO:0015002	heme-copper terminal oxidase activity
0.33	GO:0016675	oxidoreductase activity, acting on a heme group of donors
0.33	GO:0015078	hydrogen ion transmembrane transporter activity
0.33	GO:0009055	electron transfer activity

0.61	GO:0005840	ribosome
0.36	GO:0030686	90S preribosome
0.36	GO:0032040	small-subunit processome
0.35	GO:0044445	cytosolic part
0.34	GO:0044446	intracellular organelle part
0.33	GO:0005739	mitochondrion
0.33	GO:0031975	envelope
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:1.9

GO:0016675

tr|T1G8A7|T1G8A7_HELRO
Uncharacterized protein
Search

0.68	Ras-specific guanine nucleotide-releasing factor RalGPS1

0.77	GO:0007264	small GTPase mediated signal transduction
0.66	GO:0065009	regulation of molecular function
0.62	GO:0032485	regulation of Ral protein signal transduction

0.75	GO:0005085	guanyl-nucleotide exchange factor activity
0.52	GO:0017160	Ral GTPase binding

0.45	GO:0005622	intracellular
0.33	GO:0005886	plasma membrane

tr|T1G8A8|T1G8A8_HELRO
Uncharacterized protein
Search

0.10	Rho guanine nucleotide exchange factor 7 (Fragment)

0.72	GO:0035023	regulation of Rho protein signal transduction
0.63	GO:0065009	regulation of molecular function
0.51	GO:0023056	positive regulation of signaling
0.51	GO:0010647	positive regulation of cell communication
0.50	GO:0048584	positive regulation of response to stimulus
0.48	GO:0007165	signal transduction
0.45	GO:1903676	positive regulation of cap-dependent translational initiation
0.44	GO:0036493	positive regulation of translation in response to endoplasmic reticulum stress
0.44	GO:1903898	negative regulation of PERK-mediated unfolded protein response
0.44	GO:1990441	negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress

0.72	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.52	GO:0005070	SH3/SH2 adaptor activity
0.45	GO:0071074	eukaryotic initiation factor eIF2 binding
0.42	GO:0030971	receptor tyrosine kinase binding
0.42	GO:0046875	ephrin receptor binding
0.42	GO:0004860	protein kinase inhibitor activity
0.41	GO:0032947	protein complex scaffold activity
0.41	GO:0045296	cadherin binding
0.40	GO:0019904	protein domain specific binding
0.33	GO:0016301	kinase activity

0.43	GO:0097482	muscle cell postsynaptic specialization
0.42	GO:0000164	protein phosphatase type 1 complex
0.40	GO:0005911	cell-cell junction
0.40	GO:0012506	vesicle membrane
0.39	GO:0005783	endoplasmic reticulum
0.37	GO:0005840	ribosome
0.37	GO:0030027	lamellipodium
0.36	GO:0043025	neuronal cell body
0.36	GO:0043005	neuron projection
0.36	GO:0000322	storage vacuole

tr|T1G8A9|T1G8A9_HELRO
Uncharacterized protein
Search

0.38	Carbonic anhydrase

0.54

GO:0006730

one-carbon metabolic process

0.63	GO:0004089	carbonate dehydratase activity
0.49	GO:0008270	zinc ion binding

0.41	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.63

EC:4.2.1.1

GO:0004089

tr|T1G8B0|T1G8B0_HELRO
Uncharacterized protein
Search

0.26	Serine hydroxymethyltransferase

0.77	GO:0019264	glycine biosynthetic process from serine
0.74	GO:0035999	tetrahydrofolate interconversion
0.53	GO:0032259	methylation
0.49	GO:1904481	response to tetrahydrofolate
0.48	GO:0006565	L-serine catabolic process
0.46	GO:0051289	protein homotetramerization
0.45	GO:0071229	cellular response to acid chemical
0.45	GO:0071417	cellular response to organonitrogen compound
0.44	GO:0046655	folic acid metabolic process
0.44	GO:0071407	cellular response to organic cyclic compound

0.78	GO:0004372	glycine hydroxymethyltransferase activity
0.66	GO:0030170	pyridoxal phosphate binding
0.53	GO:0008168	methyltransferase activity
0.49	GO:0070905	serine binding
0.47	GO:0000900	translation repressor activity, nucleic acid binding
0.45	GO:0048027	mRNA 5'-UTR binding
0.43	GO:0042803	protein homodimerization activity
0.35	GO:0008732	L-allo-threonine aldolase activity
0.34	GO:0015002	heme-copper terminal oxidase activity
0.34	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor

0.45	GO:0005829	cytosol
0.43	GO:0005634	nucleus
0.38	GO:0005739	mitochondrion
0.34	GO:0070062	extracellular exosome
0.33	GO:0019866	organelle inner membrane

0.78

EC:2.1.2.1

GO:0004372

tr|T1G8B1|T1G8B1_HELRO
Uncharacterized protein
Search

CTSC

0.66	Dipeptidyl peptidase

0.61	GO:0006508	proteolysis
0.48	GO:0001913	T cell mediated cytotoxicity
0.45	GO:2001235	positive regulation of apoptotic signaling pathway
0.44	GO:0006915	apoptotic process
0.40	GO:0044257	cellular protein catabolic process
0.37	GO:0007568	aging
0.37	GO:1903052	positive regulation of proteolysis involved in cellular protein catabolic process
0.36	GO:0010033	response to organic substance

0.72	GO:0008234	cysteine-type peptidase activity
0.48	GO:0016505	peptidase activator activity involved in apoptotic process
0.42	GO:0004175	endopeptidase activity
0.41	GO:0017171	serine hydrolase activity
0.38	GO:0031404	chloride ion binding
0.38	GO:0043621	protein self-association
0.37	GO:0019902	phosphatase binding
0.37	GO:0051087	chaperone binding
0.36	GO:0042802	identical protein binding

0.44	GO:0005813	centrosome
0.43	GO:0005764	lysosome
0.42	GO:0005654	nucleoplasm
0.41	GO:0005615	extracellular space
0.36	GO:0005794	Golgi apparatus
0.36	GO:0005783	endoplasmic reticulum
0.34	GO:1903561	extracellular vesicle
0.30	GO:0031224	intrinsic component of membrane

0.72

GO:0008234

tr|T1G8B2|T1G8B2_HELRO
Uncharacterized protein
Search

0.78	Cilia and flagella associated protein 206

0.57	GO:0035082	axoneme assembly
0.57	GO:0003341	cilium movement

0.80	GO:0031514	motile cilium
0.64	GO:0097649	A axonemal microtubule
0.63	GO:0001534	radial spoke

tr|T1G8B3|T1G8B3_HELRO
Kinesin-like protein
Search

0.10	Kinesin motor domain-containing protein (Fragment)

0.74	GO:0007018	microtubule-based movement
0.50	GO:0071801	regulation of podosome assembly
0.50	GO:0022617	extracellular matrix disassembly
0.48	GO:1903008	organelle disassembly
0.33	GO:0018193	peptidyl-amino acid modification
0.33	GO:0006475	internal protein amino acid acetylation
0.33	GO:0030705	cytoskeleton-dependent intracellular transport
0.33	GO:0016570	histone modification
0.33	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic
0.32	GO:0007019	microtubule depolymerization

0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0046983	protein dimerization activity
0.40	GO:0016887	ATPase activity
0.35	GO:0008663	2',3'-cyclic-nucleotide 2'-phosphodiesterase activity
0.34	GO:0004381	fucosylgalactoside 3-alpha-galactosyltransferase activity
0.33	GO:0004535	poly(A)-specific ribonuclease activity

0.70	GO:0005874	microtubule
0.50	GO:0002102	podosome
0.47	GO:0005871	kinesin complex
0.44	GO:0031982	vesicle
0.34	GO:0031514	motile cilium
0.33	GO:0005829	cytosol
0.33	GO:0000178	exosome (RNase complex)
0.30	GO:0031224	intrinsic component of membrane

0.40

GO:0016887

tr|T1G8B4|T1G8B4_HELRO
Uncharacterized protein
Search

IFT140

0.95	WD and tetratricopeptide repeats protein 2

0.67	GO:0035721	intraciliary retrograde transport
0.64	GO:1990403	embryonic brain development
0.63	GO:0035845	photoreceptor cell outer segment organization
0.62	GO:0061512	protein localization to cilium
0.62	GO:0021532	neural tube patterning
0.62	GO:0031076	embryonic camera-type eye development
0.62	GO:1902017	regulation of cilium assembly
0.61	GO:0060271	cilium assembly
0.61	GO:0042733	embryonic digit morphogenesis
0.61	GO:0008589	regulation of smoothened signaling pathway

0.35	GO:0003873	6-phosphofructo-2-kinase activity
0.33	GO:0003723	RNA binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.75	GO:0005929	cilium
0.66	GO:0030991	intraciliary transport particle A
0.63	GO:0032838	plasma membrane bounded cell projection cytoplasm
0.59	GO:0005815	microtubule organizing center
0.56	GO:0043005	neuron projection
0.33	GO:0005922	connexin complex
0.31	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.35	EC:2.7.1.105	GO:0003873
0.35	KEGG:R02732	GO:0003873

tr|T1G8B5|T1G8B5_HELRO
Phosphoinositide phospholipase C
Search

0.55	Phosphoinositide phospholipase C

0.72	GO:0016042	lipid catabolic process
0.63	GO:0035556	intracellular signal transduction
0.36	GO:0046673	negative regulation of compound eye retinal cell programmed cell death
0.36	GO:0016059	deactivation of rhodopsin mediated signaling
0.36	GO:2000370	positive regulation of clathrin-dependent endocytosis
0.36	GO:0043052	thermotaxis
0.36	GO:0016056	rhodopsin mediated signaling pathway
0.36	GO:0043153	entrainment of circadian clock by photoperiod
0.36	GO:0002385	mucosal immune response
0.36	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste

0.82	GO:0004435	phosphatidylinositol phospholipase C activity
0.68	GO:0005509	calcium ion binding
0.64	GO:0004871	signal transducer activity

0.45	GO:0005622	intracellular
0.36	GO:0016027	inaD signaling complex
0.34	GO:0014069	postsynaptic density
0.34	GO:0030425	dendrite
0.33	GO:0012505	endomembrane system
0.32	GO:0043227	membrane-bounded organelle

0.82	EC:3.1.4.11	GO:0004435
0.82	KEGG:R03435	GO:0004435

tr|T1G8B6|T1G8B6_HELRO
Uncharacterized protein
Search

0.50	Tyrosine-protein phosphatase

0.69	GO:0035335	peptidyl-tyrosine dephosphorylation
0.51	GO:0030073	insulin secretion
0.51	GO:1904692	positive regulation of type B pancreatic cell proliferation
0.50	GO:1990502	dense core granule maturation
0.46	GO:1901700	response to oxygen-containing compound
0.45	GO:0045944	positive regulation of transcription by RNA polymerase II
0.43	GO:0006979	response to oxidative stress
0.42	GO:0001678	cellular glucose homeostasis
0.40	GO:0071310	cellular response to organic substance
0.40	GO:0099643	signal release from synapse

0.70	GO:0004725	protein tyrosine phosphatase activity
0.48	GO:0030507	spectrin binding
0.46	GO:0044389	ubiquitin-like protein ligase binding
0.44	GO:0008134	transcription factor binding
0.36	GO:0051020	GTPase binding
0.33	GO:0004177	aminopeptidase activity
0.33	GO:0008270	zinc ion binding
0.32	GO:0003676	nucleic acid binding

0.42	GO:0030141	secretory granule
0.42	GO:0008021	synaptic vesicle
0.41	GO:0030658	transport vesicle membrane
0.40	GO:0043679	axon terminus
0.40	GO:0005634	nucleus
0.40	GO:0043235	receptor complex
0.39	GO:0030424	axon
0.38	GO:0043025	neuronal cell body
0.38	GO:0030054	cell junction
0.37	GO:0005768	endosome

0.70

GO:0004725

tr|T1G8B7|T1G8B7_HELRO
Uncharacterized protein
Search

tr|T1G8B8|T1G8B8_HELRO
Uncharacterized protein
Search

0.64	Phosphatidic acid phosphatase type 2 domain containing 2 (Fragment)

0.53	GO:0098869	cellular oxidant detoxification
0.52	GO:0046839	phospholipid dephosphorylation

0.56	GO:0042577	lipid phosphatase activity
0.55	GO:0004601	peroxidase activity

0.30

GO:0031224

intrinsic component of membrane

0.55	EC:1.11.1.7	GO:0004601
0.55	KEGG:R03532	GO:0004601

tr|T1G8B9|T1G8B9_HELRO
Uncharacterized protein
Search

0.80	SPRY domain-containing SOCS box protein 1

0.58	GO:0035556	intracellular signal transduction
0.49	GO:0007280	pole cell migration
0.48	GO:0035017	cuticle pattern formation
0.48	GO:0046843	dorsal appendage formation
0.48	GO:0007315	pole plasm assembly
0.47	GO:0007472	wing disc morphogenesis
0.45	GO:0045732	positive regulation of protein catabolic process
0.41	GO:0008104	protein localization
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.34	GO:0043565	sequence-specific DNA binding
0.33	GO:0005515	protein binding
0.33	GO:0003700	DNA binding transcription factor activity

0.49	GO:0031466	Cul5-RING ubiquitin ligase complex
0.47	GO:0045495	pole plasm
0.47	GO:0070449	elongin complex
0.45	GO:0048471	perinuclear region of cytoplasm
0.44	GO:0005938	cell cortex
0.30	GO:0016020	membrane

tr|T1G8C0|T1G8C0_HELRO
Uncharacterized protein
Search

tr|T1G8C1|T1G8C1_HELRO
Uncharacterized protein
Search

0.53	GO:0071642	positive regulation of macrophage inflammatory protein 1 alpha production
0.53	GO:0035926	chemokine (C-C motif) ligand 2 secretion
0.53	GO:0071651	positive regulation of chemokine (C-C motif) ligand 5 production
0.53	GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production
0.52	GO:0071639	positive regulation of monocyte chemotactic protein-1 production
0.52	GO:1905517	macrophage migration
0.50	GO:1990266	neutrophil migration
0.45	GO:0051259	protein oligomerization
0.44	GO:0010877	lipid transport involved in lipid storage
0.42	GO:0007041	lysosomal transport

0.39	GO:0005262	calcium channel activity
0.34	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding
0.34	GO:0005217	intracellular ligand-gated ion channel activity
0.34	GO:0005351	sugar:proton symporter activity
0.34	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.33	GO:0003723	RNA binding
0.32	GO:0043565	sequence-specific DNA binding

0.49	GO:0055037	recycling endosome
0.42	GO:0005764	lysosome
0.40	GO:0098852	lytic vacuole membrane
0.36	GO:0010008	endosome membrane
0.35	GO:0005886	plasma membrane
0.34	GO:0005770	late endosome
0.34	GO:0000139	Golgi membrane
0.32	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

tr|T1G8C2|T1G8C2_HELRO
Uncharacterized protein
Search

0.68	Programmed cell death protein 6

0.42	GO:1902532	negative regulation of intracellular signal transduction
0.41	GO:0051270	regulation of cellular component movement
0.41	GO:1901844	regulation of cell communication by electrical coupling involved in cardiac conduction
0.41	GO:0055118	negative regulation of cardiac muscle contraction
0.41	GO:1901077	regulation of relaxation of muscle
0.41	GO:0010459	negative regulation of heart rate
0.41	GO:0051280	negative regulation of release of sequestered calcium ion into cytosol
0.41	GO:0036324	vascular endothelial growth factor receptor-2 signaling pathway
0.41	GO:0042994	cytoplasmic sequestering of transcription factor
0.40	GO:1901841	regulation of high voltage-gated calcium channel activity

0.70	GO:0005509	calcium ion binding
0.46	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.40	GO:0070491	repressing transcription factor binding
0.40	GO:0002020	protease binding
0.39	GO:0043495	protein membrane anchor
0.39	GO:0048306	calcium-dependent protein binding
0.39	GO:0046983	protein dimerization activity
0.38	GO:0060090	molecular adaptor activity
0.38	GO:0042802	identical protein binding
0.35	GO:0017056	structural constituent of nuclear pore

0.41	GO:0042584	chromaffin granule membrane
0.41	GO:0005783	endoplasmic reticulum
0.39	GO:0030018	Z disc
0.39	GO:0070062	extracellular exosome
0.39	GO:0031984	organelle subcompartment
0.39	GO:0031463	Cul3-RING ubiquitin ligase complex
0.38	GO:0005829	cytosol
0.38	GO:0030127	COPII vesicle coat
0.38	GO:0005634	nucleus
0.37	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network

tr|T1G8C3|T1G8C3_HELRO
Uncharacterized protein
Search

0.82	GO:0030317	flagellated sperm motility
0.79	GO:0036159	inner dynein arm assembly
0.71	GO:0060294	cilium movement involved in cell motility
0.41	GO:0070588	calcium ion transmembrane transport

0.41	GO:0005262	calcium channel activity
0.36	GO:0003777	microtubule motor activity
0.36	GO:0008017	microtubule binding
0.34	GO:0051015	actin filament binding
0.34	GO:0046983	protein dimerization activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.69	GO:0005815	microtubule organizing center
0.67	GO:0036126	sperm flagellum
0.51	GO:0005634	nucleus
0.49	GO:0005874	microtubule
0.38	GO:0005737	cytoplasm
0.34	GO:0016459	myosin complex
0.30	GO:0031224	intrinsic component of membrane

tr|T1G8C4|T1G8C4_HELRO
Uncharacterized protein
Search

FUOM

0.58	Fucose operon protein FucU

0.69	GO:0005996	monosaccharide metabolic process
0.44	GO:0060180	female mating behavior
0.42	GO:0045665	negative regulation of neuron differentiation
0.42	GO:0036065	fucosylation
0.32	GO:0016310	phosphorylation

0.76	GO:0048029	monosaccharide binding
0.63	GO:0016853	isomerase activity
0.34	GO:0004386	helicase activity
0.32	GO:0016301	kinase activity

0.37

GO:0005737

cytoplasm

0.63

EC:5

GO:0016853

tr|T1G8C5|T1G8C5_HELRO
Uncharacterized protein
Search

tr|T1G8C6|T1G8C6_HELRO
Uncharacterized protein
Search

0.70	LIM/homeobox protein Awh

0.44	GO:0048749	compound eye development
0.44	GO:0007444	imaginal disc development
0.40	GO:0060255	regulation of macromolecule metabolic process
0.38	GO:0080090	regulation of primary metabolic process
0.38	GO:0031326	regulation of cellular biosynthetic process
0.38	GO:0051171	regulation of nitrogen compound metabolic process
0.33	GO:0006508	proteolysis
0.32	GO:0006351	transcription, DNA-templated
0.32	GO:0016310	phosphorylation

0.55	GO:0003677	DNA binding
0.53	GO:0046872	metal ion binding
0.39	GO:0003700	DNA binding transcription factor activity
0.33	GO:0019205	nucleobase-containing compound kinase activity
0.33	GO:0004252	serine-type endopeptidase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005634	nucleus
0.37	GO:0008537	proteasome activator complex
0.30	GO:0016020	membrane

0.33

GO:0004252

tr|T1G8C7|T1G8C7_HELRO
Uncharacterized protein
Search

0.43	Homeobox domain protein

0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:0010468	regulation of gene expression
0.44	GO:1904747	positive regulation of apoptotic process involved in development
0.44	GO:0007501	mesodermal cell fate specification
0.35	GO:0008283	cell proliferation
0.35	GO:0006915	apoptotic process
0.35	GO:0048513	animal organ development

0.61	GO:0043565	sequence-specific DNA binding
0.35	GO:0005515	protein binding
0.33	GO:0003700	DNA binding transcription factor activity

0.61	GO:0005634	nucleus
0.30	GO:0044425	membrane part

tr|T1G8C8|T1G8C8_HELRO
Uncharacterized protein
Search

0.50	Microfibril-associated glycoprotein 4

0.69	GO:0050767	regulation of neurogenesis
0.66	GO:0007155	cell adhesion
0.54	GO:0007596	blood coagulation
0.43	GO:0010519	negative regulation of phospholipase activity
0.43	GO:0051005	negative regulation of lipoprotein lipase activity
0.43	GO:0055091	phospholipid homeostasis
0.42	GO:0050996	positive regulation of lipid catabolic process
0.42	GO:0070328	triglyceride homeostasis
0.42	GO:0048844	artery morphogenesis
0.42	GO:0042632	cholesterol homeostasis

0.42	GO:0004859	phospholipase inhibitor activity
0.42	GO:0005178	integrin binding
0.40	GO:0008083	growth factor activity
0.36	GO:0008233	peptidase activity

0.67	GO:0031012	extracellular matrix
0.41	GO:0005769	early endosome
0.40	GO:0009986	cell surface
0.39	GO:0005615	extracellular space
0.39	GO:0005794	Golgi apparatus
0.30	GO:0016020	membrane

0.36

GO:0008233

tr|T1G8C9|T1G8C9_HELRO
Uncharacterized protein
Search

tr|T1G8D0|T1G8D0_HELRO
Uncharacterized protein
Search

0.54

Ficolin-1

0.73	GO:0001525	angiogenesis
0.70	GO:0043066	negative regulation of apoptotic process
0.53	GO:0051005	negative regulation of lipoprotein lipase activity
0.51	GO:0070328	triglyceride homeostasis
0.50	GO:0007596	blood coagulation
0.50	GO:2000351	regulation of endothelial cell apoptotic process
0.42	GO:0006461	protein complex assembly
0.42	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.42	GO:0019216	regulation of lipid metabolic process
0.42	GO:0001775	cell activation

0.47	GO:0004857	enzyme inhibitor activity
0.45	GO:0042802	identical protein binding
0.42	GO:0030674	protein binding, bridging
0.42	GO:0005102	receptor binding
0.40	GO:0005509	calcium ion binding
0.37	GO:0050839	cell adhesion molecule binding
0.37	GO:0030545	receptor regulator activity
0.36	GO:0032403	protein complex binding
0.35	GO:0003723	RNA binding

0.68	GO:0005615	extracellular space
0.39	GO:0005578	proteinaceous extracellular matrix
0.37	GO:0043234	protein complex
0.37	GO:0005769	early endosome
0.37	GO:0009986	cell surface
0.36	GO:0005794	Golgi apparatus
0.30	GO:0016020	membrane

tr|T1G8D1|T1G8D1_HELRO
Uncharacterized protein
Search

0.58	GSX-ANTP class homeobox protein (Fragment)

0.54	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.53	GO:0010468	regulation of gene expression
0.36	GO:0007275	multicellular organism development
0.34	GO:0007601	visual perception
0.34	GO:1902679	negative regulation of RNA biosynthetic process
0.34	GO:0006366	transcription by RNA polymerase II

0.61	GO:0043565	sequence-specific DNA binding
0.38	GO:0008289	lipid binding
0.36	GO:0003700	DNA binding transcription factor activity
0.35	GO:0004000	adenosine deaminase activity
0.34	GO:0008134	transcription factor binding

0.61

GO:0005634

nucleus

0.35

GO:0004000

tr|T1G8D2|T1G8D2_HELRO
Uncharacterized protein
Search

0.60	Heterotrimeric guanine nucleotide-binding protein beta subunit

0.61	GO:0007165	signal transduction
0.45	GO:0003371	establishment or maintenance of cytoskeleton polarity involved in ameboidal cell migration
0.45	GO:0003379	establishment of cell polarity involved in gastrulation cell migration
0.44	GO:0048383	mesectoderm development
0.44	GO:0043519	regulation of myosin II filament organization
0.44	GO:0061343	cell adhesion involved in heart morphogenesis
0.43	GO:0055059	asymmetric neuroblast division
0.43	GO:0060027	convergent extension involved in gastrulation
0.43	GO:0010470	regulation of gastrulation
0.35	GO:0046662	regulation of oviposition

0.37	GO:0051020	GTPase binding
0.37	GO:0032403	protein complex binding
0.34	GO:0004402	histone acetyltransferase activity
0.33	GO:0004871	signal transducer activity
0.33	GO:0003743	translation initiation factor activity

0.42	GO:1905360	GTPase complex
0.41	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.38	GO:0098797	plasma membrane protein complex
0.38	GO:0043209	myelin sheath
0.37	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0030425	dendrite
0.33	GO:0019013	viral nucleocapsid
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0004402

tr|T1G8D3|T1G8D3_HELRO
Uncharacterized protein
Search

tr|T1G8D4|T1G8D4_HELRO
Uncharacterized protein
Search

SRPRB

0.86	Signal recognition particle receptor subunit beta

0.35	GO:0036498	IRE1-mediated unfolded protein response
0.34	GO:0042157	lipoprotein metabolic process
0.34	GO:0006869	lipid transport

0.57	GO:0032550	purine ribonucleoside binding
0.57	GO:0032561	guanyl ribonucleotide binding
0.48	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0005047	signal recognition particle binding
0.34	GO:0008289	lipid binding
0.32	GO:0016787	hydrolase activity
0.32	GO:0003676	nucleic acid binding

0.51	GO:0005881	cytoplasmic microtubule
0.48	GO:0005785	signal recognition particle receptor complex
0.43	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016787

tr|T1G8D5|T1G8D5_HELRO
Uncharacterized protein
Search

0.39	Serine/threonine-protein kinase PAK 3

0.63	GO:0006468	protein phosphorylation
0.55	GO:1990872	negative regulation of sterol import by negative regulation of transcription from RNA polymerase II promoter
0.54	GO:0007232	osmosensory signaling pathway via Sho1 osmosensor
0.54	GO:0007121	bipolar cellular bud site selection
0.53	GO:0035376	sterol import
0.53	GO:0001402	signal transduction involved in filamentous growth
0.52	GO:0034063	stress granule assembly
0.52	GO:0007118	budding cell apical bud growth
0.52	GO:0007124	pseudohyphal growth
0.52	GO:0000011	vacuole inheritance

0.64	GO:0004672	protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0005057	signal transducer activity, downstream of receptor
0.40	GO:0048365	Rac GTPase binding
0.35	GO:0031435	mitogen-activated protein kinase kinase kinase binding
0.34	GO:0043141	ATP-dependent 5'-3' DNA helicase activity
0.32	GO:0046872	metal ion binding

0.51	GO:0000131	incipient cellular bud site
0.50	GO:0043332	mating projection tip
0.42	GO:0005634	nucleus
0.38	GO:0071521	Cdc42 GTPase complex
0.38	GO:0120105	actomyosin contractile ring, intermediate layer
0.37	GO:0051286	cell tip
0.37	GO:0005876	spindle microtubule
0.34	GO:0043204	perikaryon
0.34	GO:0030425	dendrite
0.34	GO:0097255	R2TP complex

0.34

EC:3.6.1

GO:0043141

tr|T1G8D6|T1G8D6_HELRO
Uncharacterized protein
Search

0.34	Cytochrome C oxidase assembly factor

0.30

GO:0044425

membrane part

tr|T1G8D7|T1G8D7_HELRO
Uncharacterized protein
Search

tr|T1G8D8|T1G8D8_HELRO
Uncharacterized protein
Search

PGAP2

0.75	Post-GPI attachment to proteins factor

0.40	GO:0006506	GPI anchor biosynthetic process
0.38	GO:0015031	protein transport
0.37	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
0.37	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
0.36	GO:0042770	signal transduction in response to DNA damage
0.33	GO:0006412	translation

0.39	GO:0008565	protein transporter activity
0.34	GO:0003735	structural constituent of ribosome

0.39	GO:0000139	Golgi membrane
0.39	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0005634	nucleus
0.33	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

tr|T1G8D9|T1G8D9_HELRO
Uncharacterized protein
Search

tr|T1G8E0|T1G8E0_HELRO
Uncharacterized protein
Search

0.53	GO:0030433	ubiquitin-dependent ERAD pathway
0.49	GO:0016567	protein ubiquitination
0.36	GO:1904380	endoplasmic reticulum mannose trimming
0.34	GO:0007417	central nervous system development
0.32	GO:0006355	regulation of transcription, DNA-templated

0.50	GO:0004842	ubiquitin-protein transferase activity
0.45	GO:0016874	ligase activity
0.43	GO:0008270	zinc ion binding
0.34	GO:0061659	ubiquitin-like protein ligase activity
0.33	GO:0005515	protein binding
0.32	GO:0003677	DNA binding

0.48	GO:0005783	endoplasmic reticulum
0.37	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0031984	organelle subcompartment
0.32	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.45	EC:6	GO:0016874
0.50	KEGG:R03876	GO:0004842

tr|T1G8E1|T1G8E1_HELRO
Uncharacterized protein
Search

tr|T1G8E2|T1G8E2_HELRO
Uncharacterized protein
Search

tr|T1G8E3|T1G8E3_HELRO
Uncharacterized protein
Search

0.59	GO:0007165	signal transduction
0.44	GO:0016199	axon midline choice point recognition
0.41	GO:0043547	positive regulation of GTPase activity
0.36	GO:0006807	nitrogen compound metabolic process
0.34	GO:0051056	regulation of small GTPase mediated signal transduction

0.41	GO:0005096	GTPase activator activity
0.30	GO:0003824	catalytic activity

0.67	GO:0005856	cytoskeleton
0.35	GO:0005737	cytoplasm
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|T1G8E4|T1G8E4_HELRO
Uncharacterized protein
Search

0.75	GO:0007016	cytoskeletal anchoring at plasma membrane
0.71	GO:0001558	regulation of cell growth
0.65	GO:0030866	cortical actin cytoskeleton organization
0.44	GO:0002175	protein localization to paranode region of axon
0.44	GO:0048812	neuron projection morphogenesis
0.43	GO:0030913	paranodal junction assembly
0.43	GO:0071205	protein localization to juxtaparanode region of axon
0.43	GO:0043217	myelin maintenance
0.42	GO:0072659	protein localization to plasma membrane
0.41	GO:0048036	central complex development

0.68	GO:0008092	cytoskeletal protein binding
0.53	GO:0005198	structural molecule activity
0.41	GO:0004725	protein tyrosine phosphatase activity
0.33	GO:0046982	protein heterodimerization activity
0.32	GO:0003676	nucleic acid binding

0.69	GO:0005856	cytoskeleton
0.68	GO:0005911	cell-cell junction
0.51	GO:0005886	plasma membrane
0.43	GO:0044224	juxtaparanode region of axon
0.43	GO:0033270	paranode region of axon
0.42	GO:0014069	postsynaptic density
0.41	GO:0031252	cell leading edge
0.34	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.41

GO:0004725

tr|T1G8E5|T1G8E5_HELRO
Uncharacterized protein
Search

RPL26

0.79	Oxodicarboxylate carrier protein (Fragment)

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:1902167	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
0.53	GO:0009059	macromolecule biosynthetic process
0.52	GO:1904803	regulation of translation involved in cellular response to UV
0.52	GO:1902164	positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
0.51	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
0.51	GO:0042273	ribosomal large subunit biogenesis
0.50	GO:0071480	cellular response to gamma radiation

0.64	GO:0003735	structural constituent of ribosome
0.48	GO:0048027	mRNA 5'-UTR binding
0.34	GO:0005515	protein binding
0.33	GO:0046872	metal ion binding

0.71	GO:0015934	large ribosomal subunit
0.52	GO:0022626	cytosolic ribosome
0.45	GO:0005730	nucleolus
0.44	GO:0005654	nucleoplasm
0.35	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

tr|T1G8E6|T1G8E6_HELRO
Uncharacterized protein
Search

0.65	Major facilitator superfamily domain-containing protein 1

0.54	GO:0055085	transmembrane transport
0.34	GO:0006260	DNA replication

0.33

GO:0003677

DNA binding

0.30

GO:0016020

membrane

tr|T1G8E7|T1G8E7_HELRO
Uncharacterized protein
Search

tr|T1G8E8|T1G8E8_HELRO
Uncharacterized protein
Search

0.50

Tenascin

0.76	GO:0001525	angiogenesis
0.73	GO:0043066	negative regulation of apoptotic process
0.55	GO:0051005	negative regulation of lipoprotein lipase activity
0.53	GO:0070328	triglyceride homeostasis
0.51	GO:2000351	regulation of endothelial cell apoptotic process
0.45	GO:0007596	blood coagulation
0.43	GO:0019216	regulation of lipid metabolic process
0.42	GO:0007155	cell adhesion
0.41	GO:0001666	response to hypoxia
0.40	GO:0051260	protein homooligomerization

0.49	GO:0004857	enzyme inhibitor activity
0.46	GO:0042802	identical protein binding
0.40	GO:0005509	calcium ion binding
0.38	GO:0005102	receptor binding
0.38	GO:0042302	structural constituent of cuticle
0.38	GO:0050839	cell adhesion molecule binding
0.37	GO:0030545	receptor regulator activity
0.37	GO:0032403	protein complex binding
0.37	GO:0030674	protein binding, bridging
0.35	GO:0003723	RNA binding

0.69	GO:0005615	extracellular space
0.40	GO:0005578	proteinaceous extracellular matrix
0.38	GO:0005769	early endosome
0.37	GO:0009986	cell surface
0.36	GO:0005794	Golgi apparatus
0.34	GO:0043234	protein complex
0.30	GO:0016020	membrane

tr|T1G8E9|T1G8E9_HELRO
Uncharacterized protein
Search

0.48	Fibrinogen C domain-containing protein 1

0.73	GO:0001525	angiogenesis
0.70	GO:0043066	negative regulation of apoptotic process
0.53	GO:0051005	negative regulation of lipoprotein lipase activity
0.51	GO:0070328	triglyceride homeostasis
0.51	GO:0007596	blood coagulation
0.50	GO:2000351	regulation of endothelial cell apoptotic process
0.46	GO:0001775	cell activation
0.46	GO:0051258	protein polymerization
0.42	GO:0019216	regulation of lipid metabolic process
0.42	GO:0007154	cell communication

0.48	GO:0004857	enzyme inhibitor activity
0.47	GO:0030674	protein binding, bridging
0.45	GO:0042802	identical protein binding
0.45	GO:0005102	receptor binding
0.37	GO:0050839	cell adhesion molecule binding
0.37	GO:0030545	receptor regulator activity
0.36	GO:0032403	protein complex binding
0.36	GO:0005272	sodium channel activity
0.36	GO:0008528	G-protein coupled peptide receptor activity
0.34	GO:0003723	RNA binding

0.69	GO:0005615	extracellular space
0.40	GO:0043234	protein complex
0.40	GO:0005578	proteinaceous extracellular matrix
0.37	GO:0005769	early endosome
0.37	GO:0009986	cell surface
0.36	GO:0005794	Golgi apparatus
0.30	GO:0016020	membrane

tr|T1G8F0|T1G8F0_HELRO
Uncharacterized protein
Search

0.68	Putative syntaxin-binding protein 2

0.43	GO:0006887	exocytosis
0.40	GO:0048278	vesicle docking
0.38	GO:0006470	protein dephosphorylation
0.37	GO:0065007	biological regulation
0.37	GO:0051601	exocyst localization
0.37	GO:0044265	cellular macromolecule catabolic process
0.37	GO:0023052	signaling
0.37	GO:0009190	cyclic nucleotide biosynthetic process
0.37	GO:0007154	cell communication
0.36	GO:0000278	mitotic cell cycle

0.39	GO:0008484	sulfuric ester hydrolase activity
0.38	GO:0004721	phosphoprotein phosphatase activity
0.37	GO:0005509	calcium ion binding
0.37	GO:0005080	protein kinase C binding
0.37	GO:0019888	protein phosphatase regulator activity
0.36	GO:0016849	phosphorus-oxygen lyase activity
0.36	GO:0000149	SNARE binding
0.36	GO:0046875	ephrin receptor binding
0.36	GO:0061630	ubiquitin protein ligase activity
0.35	GO:0003756	protein disulfide isomerase activity

0.40	GO:0000145	exocyst
0.37	GO:0035145	exon-exon junction complex
0.37	GO:0097458	neuron part
0.37	GO:0000159	protein phosphatase type 2A complex
0.37	GO:0005844	polysome
0.36	GO:0120038	plasma membrane bounded cell projection part
0.35	GO:0005829	cytosol
0.35	GO:0044456	synapse part
0.34	GO:0005783	endoplasmic reticulum
0.30	GO:0016020	membrane

0.39

EC:3.1.6

GO:0008484

tr|T1G8F1|T1G8F1_HELRO
Uncharacterized protein
Search

0.53	Nuclear receptor

0.78	GO:0043401	steroid hormone mediated signaling pathway
0.60	GO:0030522	intracellular receptor signaling pathway
0.58	GO:0097659	nucleic acid-templated transcription
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0010467	gene expression
0.53	GO:0034645	cellular macromolecule biosynthetic process
0.41	GO:1902680	positive regulation of RNA biosynthetic process
0.37	GO:0001889	liver development

0.74	GO:0003707	steroid hormone receptor activity
0.64	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.43	GO:0001012	RNA polymerase II regulatory region DNA binding
0.42	GO:0003690	double-stranded DNA binding
0.42	GO:0046982	protein heterodimerization activity
0.36	GO:0042826	histone deacetylase binding
0.35	GO:0042803	protein homodimerization activity
0.34	GO:0043422	protein kinase B binding

0.61	GO:0005634	nucleus
0.41	GO:0070013	intracellular organelle lumen
0.38	GO:0044446	intracellular organelle part
0.33	GO:0045177	apical part of cell
0.33	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0043025	neuronal cell body
0.33	GO:0030425	dendrite
0.33	GO:0015629	actin cytoskeleton
0.32	GO:0005829	cytosol
0.32	GO:0005694	chromosome

0.33

GO:0016773

tr|T1G8F2|T1G8F2_HELRO
Uncharacterized protein
Search

0.97	Putative calcium-independent phospholip (Fragment)

0.72	GO:0016042	lipid catabolic process
0.36	GO:0070328	triglyceride homeostasis
0.36	GO:1902884	positive regulation of response to oxidative stress

0.51	GO:0016787	hydrolase activity
0.34	GO:0019904	protein domain specific binding
0.32	GO:0008270	zinc ion binding

0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.51

GO:0016787

tr|T1G8F3|T1G8F3_HELRO
mRNA-capping enzyme
Search

RNGTT

0.84	mRNA-capping enzyme

0.84	GO:0098507	polynucleotide 5' dephosphorylation
0.75	GO:0006370	7-methylguanosine mRNA capping
0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.36	GO:0006266	DNA ligation
0.35	GO:0006310	DNA recombination
0.35	GO:0006281	DNA repair
0.34	GO:0006366	transcription by RNA polymerase II
0.34	GO:0007018	microtubule-based movement
0.33	GO:0016032	viral process
0.33	GO:0055114	oxidation-reduction process

0.84	GO:0004651	polynucleotide 5'-phosphatase activity
0.84	GO:0004484	mRNA guanylyltransferase activity
0.78	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.74	GO:0004725	protein tyrosine phosphatase activity
0.60	GO:0032550	purine ribonucleoside binding
0.59	GO:0019001	guanyl nucleotide binding
0.54	GO:0050355	triphosphatase activity
0.50	GO:0032553	ribonucleotide binding
0.50	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0003910	DNA ligase (ATP) activity

0.60	GO:0005634	nucleus
0.34	GO:0016459	myosin complex
0.33	GO:0031974	membrane-enclosed lumen

0.84	EC:3.1.3.33	GO:0004651
0.54	KEGG:R00138	GO:0050355

tr|T1G8F4|T1G8F4_HELRO
Uncharacterized protein
Search

0.62	GO:0007219	Notch signaling pathway
0.56	GO:0030154	cell differentiation
0.55	GO:0045967	negative regulation of growth rate
0.55	GO:0003192	mitral valve formation
0.55	GO:0003169	coronary vein morphogenesis
0.55	GO:2001027	negative regulation of endothelial cell chemotaxis
0.54	GO:0003180	aortic valve morphogenesis
0.54	GO:0003213	cardiac right atrium morphogenesis
0.54	GO:0071372	cellular response to follicle-stimulating hormone stimulus
0.54	GO:2000974	negative regulation of pro-B cell differentiation

0.70	GO:0005509	calcium ion binding
0.51	GO:0005112	Notch binding
0.51	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.50	GO:0004872	receptor activity
0.50	GO:0031490	chromatin DNA binding
0.50	GO:0001047	core promoter binding
0.47	GO:0004857	enzyme inhibitor activity
0.47	GO:0046982	protein heterodimerization activity
0.46	GO:0005201	extracellular matrix structural constituent
0.45	GO:0019899	enzyme binding

0.54	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex
0.50	GO:0016324	apical plasma membrane
0.49	GO:0005912	adherens junction
0.49	GO:0043235	receptor complex
0.47	GO:0009986	cell surface
0.46	GO:0031410	cytoplasmic vesicle
0.45	GO:0005783	endoplasmic reticulum
0.44	GO:0005578	proteinaceous extracellular matrix
0.42	GO:0005634	nucleus
0.39	GO:0120025	plasma membrane bounded cell projection

0.39

GO:0004222

tr|T1G8F5|T1G8F5_HELRO
Uncharacterized protein
Search

tr|T1G8F6|T1G8F6_HELRO
Uncharacterized protein
Search

0.77	GO:0035725	sodium ion transmembrane transport
0.36	GO:0070207	protein homotrimerization
0.36	GO:0055078	sodium ion homeostasis
0.36	GO:0071467	cellular response to pH
0.36	GO:0050891	multicellular organismal water homeostasis
0.35	GO:0045944	positive regulation of transcription by RNA polymerase II
0.35	GO:0051726	regulation of cell cycle
0.34	GO:0006468	protein phosphorylation

0.81	GO:0005272	sodium channel activity
0.41	GO:0099094	ligand-gated cation channel activity
0.36	GO:0004693	cyclin-dependent protein serine/threonine kinase activity
0.36	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity
0.36	GO:0050699	WW domain binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.36	GO:0070985	TFIIK complex
0.35	GO:0034706	sodium channel complex
0.35	GO:0005887	integral component of plasma membrane
0.35	GO:0009897	external side of plasma membrane
0.35	GO:0070062	extracellular exosome
0.32	GO:0005737	cytoplasm

0.36

EC:2.7.11.22

GO:0004693

tr|T1G8F7|T1G8F7_HELRO
Uncharacterized protein
Search

0.72	Transcription initiation factor IIF auxiliary subunit

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.51	GO:0016573	histone acetylation
0.46	GO:0097355	protein localization to heterochromatin
0.44	GO:0070828	heterochromatin organization
0.43	GO:0043486	histone exchange
0.42	GO:0006413	translational initiation
0.40	GO:1902679	negative regulation of RNA biosynthetic process
0.35	GO:0040008	regulation of growth

0.49	GO:0008022	protein C-terminus binding
0.43	GO:0003743	translation initiation factor activity
0.42	GO:0004402	histone acetyltransferase activity
0.34	GO:0005200	structural constituent of cytoskeleton
0.33	GO:0003700	DNA binding transcription factor activity
0.32	GO:0003677	DNA binding

0.81	GO:0000812	Swr1 complex
0.77	GO:0035267	NuA4 histone acetyltransferase complex
0.48	GO:0031965	nuclear membrane
0.34	GO:0016363	nuclear matrix
0.34	GO:0005669	transcription factor TFIID complex
0.34	GO:0005849	mRNA cleavage factor complex
0.30	GO:0031224	intrinsic component of membrane

0.42

GO:0004402

tr|T1G8F8|T1G8F8_HELRO
Uncharacterized protein
Search

0.68	Segmentation protein paired

0.70	GO:0007275	multicellular organism development
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.41	GO:0030154	cell differentiation
0.38	GO:1902680	positive regulation of RNA biosynthetic process

0.62	GO:0043565	sequence-specific DNA binding
0.45	GO:0001012	RNA polymerase II regulatory region DNA binding
0.44	GO:0003690	double-stranded DNA binding
0.40	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.33	GO:0004000	adenosine deaminase activity

0.61

GO:0005634

nucleus

0.33

GO:0004000

tr|T1G8F9|T1G8F9_HELRO
Uncharacterized protein
Search

0.79	Putative syntaxin-binding protein 2 (Fragment)

0.35	GO:0070647	protein modification by small protein conjugation or removal
0.34	GO:0007596	blood coagulation
0.34	GO:0007167	enzyme linked receptor protein signaling pathway
0.34	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.33	GO:0045292	mRNA cis splicing, via spliceosome
0.33	GO:0006508	proteolysis
0.33	GO:0006741	NADP biosynthetic process
0.33	GO:0038065	collagen-activated signaling pathway
0.33	GO:0006301	postreplication repair
0.33	GO:0019674	NAD metabolic process

0.35	GO:0008484	sulfuric ester hydrolase activity
0.34	GO:0005509	calcium ion binding
0.34	GO:0140096	catalytic activity, acting on a protein
0.34	GO:0016740	transferase activity
0.33	GO:0038064	collagen receptor activity
0.33	GO:0008270	zinc ion binding
0.33	GO:0004333	fumarate hydratase activity
0.33	GO:0031683	G-protein beta/gamma-subunit complex binding
0.33	GO:0000062	fatty-acyl-CoA binding
0.33	GO:0017171	serine hydrolase activity

0.33	GO:0005634	nucleus
0.33	GO:0032991	macromolecular complex
0.33	GO:0005576	extracellular region
0.33	GO:0031514	motile cilium
0.33	GO:0000793	condensed chromosome
0.32	GO:0044446	intracellular organelle part
0.32	GO:0005886	plasma membrane
0.32	GO:0044444	cytoplasmic part
0.30	GO:0016021	integral component of membrane

0.35	EC:3.1.6	GO:0008484
0.33	KEGG:R01082	GO:0004333

tr|T1G8G0|T1G8G0_HELRO
Uncharacterized protein
Search

0.83	DNA cross-link repair protein pso2/snm1, putative

0.73	GO:0030183	B cell differentiation
0.73	GO:0000723	telomere maintenance
0.71	GO:0010212	response to ionizing radiation
0.70	GO:0006302	double-strand break repair
0.67	GO:0033151	V(D)J recombination
0.65	GO:0036297	interstrand cross-link repair
0.63	GO:0000726	non-recombinational repair
0.61	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.48	GO:0002250	adaptive immune response
0.38	GO:0006414	translational elongation

0.72	GO:0008409	5'-3' exonuclease activity
0.72	GO:0000014	single-stranded DNA endodeoxyribonuclease activity
0.59	GO:0016895	exodeoxyribonuclease activity, producing 5'-phosphomonoesters
0.58	GO:0003684	damaged DNA binding
0.38	GO:0003746	translation elongation factor activity
0.37	GO:0005515	protein binding
0.36	GO:0044877	macromolecular complex binding
0.34	GO:0008080	N-acetyltransferase activity
0.33	GO:0016301	kinase activity
0.33	GO:0016491	oxidoreductase activity

0.78	GO:0070419	nonhomologous end joining complex
0.64	GO:0000784	nuclear chromosome, telomeric region
0.62	GO:0005794	Golgi apparatus
0.61	GO:0005654	nucleoplasm
0.40	GO:0005853	eukaryotic translation elongation factor 1 complex
0.37	GO:0005813	centrosome
0.30	GO:0031224	intrinsic component of membrane

0.59

EC:3.1.11

GO:0016895

tr|T1G8G1|T1G8G1_HELRO
Uncharacterized protein
Search

0.53	GO:0055114	oxidation-reduction process
0.45	GO:0032981	mitochondrial respiratory chain complex I assembly
0.35	GO:0006351	transcription, DNA-templated
0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression
0.33	GO:0000413	protein peptidyl-prolyl isomerization

0.54	GO:0016491	oxidoreductase activity
0.38	GO:0004075	biotin carboxylase activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0046872	metal ion binding
0.34	GO:0003677	DNA binding
0.33	GO:0003755	peptidyl-prolyl cis-trans isomerase activity

0.44	GO:0005747	mitochondrial respiratory chain complex I
0.35	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.54

GO:0016491

tr|T1G8G2|T1G8G2_HELRO
Uncharacterized protein
Search

0.47

Tenascin

0.75	GO:0001525	angiogenesis
0.72	GO:0043066	negative regulation of apoptotic process
0.54	GO:0051005	negative regulation of lipoprotein lipase activity
0.52	GO:0070328	triglyceride homeostasis
0.51	GO:2000351	regulation of endothelial cell apoptotic process
0.47	GO:0007596	blood coagulation
0.43	GO:0019216	regulation of lipid metabolic process
0.42	GO:0007155	cell adhesion
0.42	GO:0006461	protein complex assembly
0.41	GO:0001666	response to hypoxia

0.48	GO:0004857	enzyme inhibitor activity
0.46	GO:0042802	identical protein binding
0.41	GO:0005102	receptor binding
0.40	GO:0030674	protein binding, bridging
0.40	GO:0005509	calcium ion binding
0.38	GO:0050839	cell adhesion molecule binding
0.37	GO:0001104	RNA polymerase II transcription cofactor activity
0.37	GO:0030545	receptor regulator activity
0.37	GO:0032403	protein complex binding
0.35	GO:0003723	RNA binding

0.69	GO:0005615	extracellular space
0.40	GO:0005578	proteinaceous extracellular matrix
0.38	GO:0005769	early endosome
0.38	GO:0043234	protein complex
0.37	GO:0009986	cell surface
0.36	GO:0005794	Golgi apparatus
0.36	GO:0044451	nucleoplasm part
0.30	GO:0016020	membrane

tr|T1G8G3|T1G8G3_HELRO
Uncharacterized protein
Search

0.49	Fibrinogen C domain-containing protein 1

0.68	GO:0001525	angiogenesis
0.66	GO:0043066	negative regulation of apoptotic process
0.57	GO:0007596	blood coagulation
0.51	GO:0001775	cell activation
0.51	GO:0051005	negative regulation of lipoprotein lipase activity
0.50	GO:0051258	protein polymerization
0.49	GO:2000351	regulation of endothelial cell apoptotic process
0.49	GO:0070328	triglyceride homeostasis
0.44	GO:0007154	cell communication
0.44	GO:0023052	signaling

0.51	GO:0030674	protein binding, bridging
0.49	GO:0005102	receptor binding
0.46	GO:0004857	enzyme inhibitor activity
0.44	GO:0042802	identical protein binding
0.39	GO:0050839	cell adhesion molecule binding
0.38	GO:0015081	sodium ion transmembrane transporter activity
0.37	GO:0005326	neurotransmitter transporter activity
0.36	GO:0015294	solute:cation symporter activity
0.36	GO:0030545	receptor regulator activity
0.36	GO:0032403	protein complex binding

0.67	GO:0005615	extracellular space
0.43	GO:0043234	protein complex
0.39	GO:0005578	proteinaceous extracellular matrix
0.38	GO:0009986	cell surface
0.38	GO:0031091	platelet alpha granule
0.36	GO:0005769	early endosome
0.36	GO:0005938	cell cortex
0.36	GO:0098552	side of membrane
0.35	GO:0005794	Golgi apparatus
0.35	GO:0044459	plasma membrane part

0.36

EC:3.4.23

GO:0004190

tr|T1G8G4|T1G8G4_HELRO
Uncharacterized protein
Search

0.51	GO:0006032	chitin catabolic process
0.49	GO:0016998	cell wall macromolecule catabolic process
0.44	GO:0043043	peptide biosynthetic process
0.42	GO:0044267	cellular protein metabolic process
0.41	GO:0010467	gene expression
0.41	GO:0009059	macromolecule biosynthetic process

0.51	GO:0004568	chitinase activity
0.46	GO:0003735	structural constituent of ribosome
0.40	GO:0003676	nucleic acid binding

0.44	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

0.51

EC:3.2.1.14

GO:0004568

tr|T1G8G5|T1G8G5_HELRO
Uncharacterized protein
Search

tr|T1G8G6|T1G8G6_HELRO
Uncharacterized protein
Search

0.65

GO:0005581

collagen trimer

tr|T1G8G7|T1G8G7_HELRO
Calcium-transporting ATPase
Search

ATP2B2

0.47	Calcium-transporting ATPase

0.77	GO:0070588	calcium ion transmembrane transport
0.69	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.51	GO:0006874	cellular calcium ion homeostasis
0.46	GO:0007605	sensory perception of sound
0.45	GO:0030182	neuron differentiation
0.39	GO:0045299	otolith mineralization
0.38	GO:0021684	cerebellar granular layer formation
0.38	GO:0021694	cerebellar Purkinje cell layer formation
0.38	GO:0042428	serotonin metabolic process
0.38	GO:0007595	lactation

0.81	GO:0005388	calcium-transporting ATPase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0030165	PDZ domain binding
0.38	GO:0030899	calcium-dependent ATPase activity
0.37	GO:0008022	protein C-terminus binding
0.37	GO:0005516	calmodulin binding
0.36	GO:0033130	acetylcholine receptor binding
0.35	GO:0035254	glutamate receptor binding

0.41	GO:0005887	integral component of plasma membrane
0.38	GO:0043231	intracellular membrane-bounded organelle
0.37	GO:0016324	apical plasma membrane
0.37	GO:0043025	neuronal cell body
0.36	GO:0005929	cilium
0.36	GO:0005737	cytoplasm
0.36	GO:0045202	synapse
0.36	GO:0030054	cell junction
0.36	GO:0044298	cell body membrane
0.35	GO:0012505	endomembrane system

0.81

EC:3.6.3.8

GO:0005388

tr|T1G8G8|T1G8G8_HELRO
Uncharacterized protein
Search

tr|T1G8G9|T1G8G9_HELRO
Uncharacterized protein
Search

0.67	GO:0007049	cell cycle
0.62	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity
0.61	GO:2000045	regulation of G1/S transition of mitotic cell cycle
0.60	GO:1901992	positive regulation of mitotic cell cycle phase transition
0.57	GO:0008284	positive regulation of cell proliferation
0.56	GO:0010165	response to X-ray
0.54	GO:1902808	positive regulation of cell cycle G1/S phase transition
0.54	GO:0007616	long-term memory
0.54	GO:0071479	cellular response to ionizing radiation
0.53	GO:0070141	response to UV-A

0.57	GO:0019901	protein kinase binding
0.50	GO:0070064	proline-rich region binding
0.49	GO:0003714	transcription corepressor activity
0.49	GO:0042826	histone deacetylase binding
0.48	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity
0.44	GO:0008134	transcription factor binding
0.42	GO:0004672	protein kinase activity
0.38	GO:0032403	protein complex binding
0.35	GO:0060089	molecular transducer activity

0.62	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.61	GO:0005634	nucleus
0.50	GO:0070013	intracellular organelle lumen
0.49	GO:0017053	transcriptional repressor complex
0.48	GO:0000785	chromatin
0.47	GO:0005829	cytosol
0.47	GO:0005923	bicellular tight junction
0.46	GO:0012505	endomembrane system
0.44	GO:0031967	organelle envelope
0.43	GO:0031090	organelle membrane

0.48

GO:0016538

tr|T1G8H0|T1G8H0_HELRO
Uncharacterized protein
Search

IFA-1

0.91	Intermediate filament protein A

0.62

GO:0005198

structural molecule activity

0.79	GO:0005882	intermediate filament
0.32	GO:0036338	viral membrane
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1G8H1|T1G8H1_HELRO
Uncharacterized protein
Search

0.11	High mobility group protein B1

0.38	GO:0006281	DNA repair
0.37	GO:0006260	DNA replication
0.37	GO:0090579	dsDNA loop formation
0.37	GO:2001141	regulation of RNA biosynthetic process
0.37	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.37	GO:0001173	DNA-templated transcriptional start site selection
0.37	GO:0010468	regulation of gene expression
0.37	GO:0016575	histone deacetylation
0.36	GO:0006367	transcription initiation from RNA polymerase II promoter
0.36	GO:0030261	chromosome condensation

0.55	GO:0003677	DNA binding
0.49	GO:0046982	protein heterodimerization activity
0.37	GO:0017136	NAD-dependent histone deacetylase activity
0.36	GO:0070403	NAD+ binding
0.34	GO:0008270	zinc ion binding
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005634	nucleus
0.39	GO:0005694	chromosome
0.36	GO:0032040	small-subunit processome
0.35	GO:0005829	cytosol
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

tr|T1G8H2|T1G8H2_HELRO
Uncharacterized protein
Search

SC5D

0.92	Lathosterol oxidase

0.65	GO:0008610	lipid biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.48	GO:0016125	sterol metabolic process
0.48	GO:1902653	secondary alcohol biosynthetic process
0.45	GO:0001878	response to yeast
0.41	GO:0044108	cellular alcohol biosynthetic process
0.41	GO:0016128	phytosteroid metabolic process
0.39	GO:1901362	organic cyclic compound biosynthetic process
0.38	GO:0044255	cellular lipid metabolic process
0.35	GO:0007605	sensory perception of sound

0.63	GO:0005506	iron ion binding
0.54	GO:0016491	oxidoreductase activity
0.35	GO:0005201	extracellular matrix structural constituent
0.33	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
0.32	GO:0005515	protein binding
0.32	GO:0016787	hydrolase activity

0.45	GO:0044432	endoplasmic reticulum part
0.43	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.42	GO:0031984	organelle subcompartment
0.38	GO:0043233	organelle lumen
0.35	GO:0005578	proteinaceous extracellular matrix
0.30	GO:0031224	intrinsic component of membrane

0.54

GO:0016491

tr|T1G8H3|T1G8H3_HELRO
Uncharacterized protein
Search

0.56	Hox median 2 protein (Fragment)

0.55	GO:0007275	multicellular organism development
0.53	GO:1903506	regulation of nucleic acid-templated transcription
0.53	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.52	GO:0010468	regulation of gene expression
0.43	GO:0090098	positive regulation of decapentaplegic signaling pathway
0.42	GO:0060323	head morphogenesis
0.40	GO:1902680	positive regulation of RNA biosynthetic process
0.35	GO:0061448	connective tissue development
0.35	GO:0030154	cell differentiation
0.34	GO:0051960	regulation of nervous system development

0.58	GO:0043565	sequence-specific DNA binding
0.50	GO:0003700	DNA binding transcription factor activity
0.41	GO:0035326	enhancer binding
0.39	GO:0046982	protein heterodimerization activity
0.34	GO:0001012	RNA polymerase II regulatory region DNA binding
0.34	GO:0003690	double-stranded DNA binding
0.33	GO:0004743	pyruvate kinase activity
0.33	GO:0030955	potassium ion binding
0.32	GO:0000287	magnesium ion binding
0.32	GO:0016301	kinase activity

0.61	GO:0005634	nucleus
0.32	GO:0005737	cytoplasm

0.33

EC:2.7.1.40

GO:0004743

tr|T1G8H4|T1G8H4_HELRO
Uncharacterized protein
Search

0.37	GO:0016579	protein deubiquitination
0.34	GO:0006351	transcription, DNA-templated
0.34	GO:0006355	regulation of transcription, DNA-templated

0.38	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.35	GO:0043565	sequence-specific DNA binding
0.34	GO:0008270	zinc ion binding
0.34	GO:0003700	DNA binding transcription factor activity

0.34	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|T1G8H5|T1G8H5_HELRO
Uncharacterized protein
Search

tr|T1G8H6|T1G8H6_HELRO
Uncharacterized protein
Search

0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.42	GO:0007210	serotonin receptor signaling pathway
0.37	GO:0032098	regulation of appetite
0.36	GO:0095500	acetylcholine receptor signaling pathway
0.36	GO:0018108	peptidyl-tyrosine phosphorylation
0.36	GO:0018991	oviposition
0.35	GO:0007268	chemical synaptic transmission
0.35	GO:0060179	male mating behavior
0.35	GO:0019722	calcium-mediated signaling
0.35	GO:0009649	entrainment of circadian clock

0.71	GO:0004930	G-protein coupled receptor activity
0.43	GO:0099589	serotonin receptor activity
0.42	GO:0030594	neurotransmitter receptor activity
0.39	GO:0051378	serotonin binding
0.36	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.34	GO:0001653	peptide receptor activity

0.38	GO:0005886	plasma membrane
0.32	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

0.36

GO:0004715

tr|T1G8H7|T1G8H7_HELRO
Uncharacterized protein
Search

tr|T1G8H8|T1G8H8_HELRO
Uncharacterized protein
Search

0.67	RAS p21 protein activator (GTPase activating protein) 1a

0.84	GO:0046580	negative regulation of Ras protein signal transduction
0.75	GO:0043547	positive regulation of GTPase activity
0.59	GO:0007165	signal transduction
0.49	GO:0001568	blood vessel development
0.49	GO:0001953	negative regulation of cell-matrix adhesion
0.46	GO:0043066	negative regulation of apoptotic process
0.46	GO:0030833	regulation of actin filament polymerization
0.44	GO:0009653	anatomical structure morphogenesis
0.42	GO:0016319	mushroom body development
0.42	GO:0048149	behavioral response to ethanol

0.76	GO:0005096	GTPase activator activity
0.47	GO:0001784	phosphotyrosine residue binding
0.44	GO:0051020	GTPase binding
0.43	GO:0005102	receptor binding
0.34	GO:0019870	potassium channel inhibitor activity
0.34	GO:0043422	protein kinase B binding
0.34	GO:1990782	protein tyrosine kinase binding
0.34	GO:0044325	ion channel binding
0.33	GO:0032403	protein complex binding
0.33	GO:0008134	transcription factor binding

0.46	GO:0001726	ruffle
0.45	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane
0.37	GO:0005737	cytoplasm
0.33	GO:0031965	nuclear membrane
0.31	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.33	EC:1.14	GO:0016705
0.32	KEGG:R01082	GO:0004333

tr|T1G8H9|T1G8H9_HELRO
Uncharacterized protein
Search

tr|T1G8I0|T1G8I0_HELRO
Uncharacterized protein
Search

0.63	Putative 52 kDa repressor of the inhibitor of the protein kinase (Fragment)

0.56

GO:0016310

phosphorylation

0.68	GO:0046983	protein dimerization activity
0.59	GO:0016301	kinase activity

tr|T1G8I1|T1G8I1_HELRO
Uncharacterized protein
Search

tr|T1G8I2|T1G8I2_HELRO
Uncharacterized protein
Search

0.57	GO:0016567	protein ubiquitination
0.44	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.39	GO:0007283	spermatogenesis
0.37	GO:0030154	cell differentiation

0.59	GO:0008270	zinc ion binding
0.57	GO:0004842	ubiquitin-protein transferase activity
0.44	GO:0061659	ubiquitin-like protein ligase activity
0.36	GO:0016874	ligase activity

0.47	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

0.36	EC:6	GO:0016874
0.57	KEGG:R03876	GO:0004842

tr|T1G8I3|T1G8I3_HELRO
Uncharacterized protein
Search

0.58	GO:0016567	protein ubiquitination
0.42	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.40	GO:0007283	spermatogenesis
0.38	GO:0030154	cell differentiation

0.58	GO:0004842	ubiquitin-protein transferase activity
0.56	GO:0008270	zinc ion binding
0.42	GO:0061659	ubiquitin-like protein ligase activity
0.42	GO:0035091	phosphatidylinositol binding
0.35	GO:0016874	ligase activity
0.33	GO:0003676	nucleic acid binding

0.49	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.35	EC:6	GO:0016874
0.58	KEGG:R03876	GO:0004842

tr|T1G8I4|T1G8I4_HELRO
Uncharacterized protein
Search

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.63	GO:0019933	cAMP-mediated signaling
0.59	GO:0042311	vasodilation
0.52	GO:0071870	cellular response to catecholamine stimulus
0.50	GO:0046960	sensitization
0.50	GO:0060359	response to ammonium ion
0.49	GO:0060292	long term synaptic depression
0.49	GO:0001975	response to amphetamine
0.49	GO:0007190	activation of adenylate cyclase activity
0.48	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol

0.72	GO:0004930	G-protein coupled receptor activity
0.63	GO:0030594	neurotransmitter receptor activity
0.52	GO:0035240	dopamine binding
0.42	GO:0009881	photoreceptor activity
0.34	GO:0031750	D3 dopamine receptor binding
0.34	GO:0031701	angiotensin receptor binding
0.33	GO:0001965	G-protein alpha-subunit binding
0.33	GO:0051117	ATPase binding
0.33	GO:0019903	protein phosphatase binding
0.33	GO:0032403	protein complex binding

0.54	GO:0005887	integral component of plasma membrane
0.51	GO:0060170	ciliary membrane
0.49	GO:0097730	non-motile cilium
0.42	GO:0005783	endoplasmic reticulum
0.40	GO:0031526	brush border membrane
0.39	GO:0005634	nucleus
0.37	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0031984	organelle subcompartment
0.35	GO:0098793	presynapse
0.34	GO:0099501	exocytic vesicle membrane

tr|T1G8I7|T1G8I7_HELRO
Uncharacterized protein
Search

0.52	Myohemerythrin

0.40	GO:0015671	oxygen transport
0.35	GO:0007165	signal transduction
0.35	GO:0006935	chemotaxis

0.62	GO:0005506	iron ion binding
0.40	GO:0005344	oxygen carrier activity
0.36	GO:0004871	signal transducer activity

0.30

GO:0044425

membrane part

tr|T1G8I9|T1G8I9_HELRO
Uncharacterized protein
Search

0.76	GO:0051260	protein homooligomerization
0.73	GO:0071805	potassium ion transmembrane transport
0.73	GO:0034765	regulation of ion transmembrane transport
0.35	GO:0030431	sleep
0.34	GO:0006379	mRNA cleavage
0.32	GO:0006351	transcription, DNA-templated

0.78	GO:0005249	voltage-gated potassium channel activity
0.33	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.33	GO:0046872	metal ion binding
0.32	GO:0003676	nucleic acid binding

0.78

GO:0008076

voltage-gated potassium channel complex

0.33

GO:0003899

tr|T1G8J0|T1G8J0_HELRO
Uncharacterized protein
Search

0.59	GO:0035269	protein O-linked mannosylation
0.56	GO:0007411	axon guidance

0.57

GO:0015020

glucuronosyltransferase activity

0.52	GO:0005794	Golgi apparatus
0.30	GO:0016020	membrane

0.57

EC:2.4.1.17

GO:0015020

tr|T1G8J1|T1G8J1_HELRO
Uncharacterized protein
Search

0.57	Glucose-dependent insulinotropic receptor

0.35	GO:0070647	protein modification by small protein conjugation or removal
0.34	GO:0042073	intraciliary transport
0.34	GO:0060271	cilium assembly
0.34	GO:0006508	proteolysis
0.33	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:0006351	transcription, DNA-templated
0.33	GO:0006313	transposition, DNA-mediated
0.33	GO:0015074	DNA integration
0.33	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.33	GO:0016192	vesicle-mediated transport

0.35	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.34	GO:0004842	ubiquitin-protein transferase activity
0.34	GO:0031683	G-protein beta/gamma-subunit complex binding
0.33	GO:0015631	tubulin binding
0.33	GO:0043565	sequence-specific DNA binding
0.33	GO:0008270	zinc ion binding
0.33	GO:0036094	small molecule binding
0.33	GO:0003700	DNA binding transcription factor activity
0.33	GO:0004636	phosphoribosyl-ATP diphosphatase activity
0.33	GO:1901265	nucleoside phosphate binding

0.34	GO:0030992	intraciliary transport particle B
0.34	GO:0031514	motile cilium
0.33	GO:0030008	TRAPP complex
0.33	GO:0043231	intracellular membrane-bounded organelle
0.32	GO:0044444	cytoplasmic part
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.33	EC:3.6.1.31	GO:0004636
0.34	KEGG:R03876	GO:0004842

tr|T1G8J2|T1G8J2_HELRO
Uncharacterized protein
Search

0.94	Homeodmain protein (Fragment)

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.52	GO:0060442	branching involved in prostate gland morphogenesis
0.52	GO:0060526	prostate glandular acinus morphogenesis
0.47	GO:0060743	epithelial cell maturation involved in prostate gland development
0.45	GO:0048514	blood vessel morphogenesis
0.45	GO:0060687	regulation of branching involved in prostate gland morphogenesis
0.44	GO:0030539	male genitalia development
0.44	GO:0060602	branch elongation of an epithelium

0.64	GO:0043565	sequence-specific DNA binding
0.44	GO:0035326	enhancer binding
0.44	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.42	GO:0001012	RNA polymerase II regulatory region DNA binding
0.41	GO:0003682	chromatin binding
0.41	GO:0003690	double-stranded DNA binding
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.42	GO:0005667	transcription factor complex
0.41	GO:0043233	organelle lumen
0.38	GO:0044446	intracellular organelle part
0.32	GO:0019013	viral nucleocapsid
0.30	GO:0016020	membrane

tr|T1G8J3|T1G8J3_HELRO
Uncharacterized protein
Search

0.48	GO:0070309	lens fiber cell morphogenesis
0.48	GO:0055007	cardiac muscle cell differentiation
0.48	GO:0060836	lymphatic endothelial cell differentiation
0.48	GO:0001946	lymphangiogenesis
0.46	GO:0000122	negative regulation of transcription by RNA polymerase II
0.46	GO:0030182	neuron differentiation
0.46	GO:0070365	hepatocyte differentiation
0.46	GO:1904252	negative regulation of bile acid metabolic process
0.45	GO:2000979	positive regulation of forebrain neuron differentiation
0.45	GO:0090425	acinar cell differentiation

0.55	GO:0003677	DNA binding
0.46	GO:0050692	DBD domain binding
0.45	GO:0050693	LBD domain binding
0.45	GO:0016922	ligand-dependent nuclear receptor binding
0.45	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.43	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.43	GO:0003714	transcription corepressor activity
0.41	GO:0001067	regulatory region nucleic acid binding
0.33	GO:0035091	phosphatidylinositol binding

0.43	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm
0.34	GO:0045178	basal part of cell
0.34	GO:0045177	apical part of cell
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1G8J4|T1G8J4_HELRO
Histone H3
Search

0.43	GO:0006334	nucleosome assembly
0.35	GO:0006352	DNA-templated transcription, initiation

0.74	GO:0046982	protein heterodimerization activity
0.55	GO:0003677	DNA binding
0.39	GO:0031491	nucleosome binding

0.75	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.36	GO:0005700	polytene chromosome
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

tr|T1G8J5|T1G8J5_HELRO
Uncharacterized protein
Search

0.57	GSX-ANTP class homeobox protein (Fragment)

0.52	GO:1903506	regulation of nucleic acid-templated transcription
0.52	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.51	GO:0010468	regulation of gene expression
0.46	GO:0030903	notochord development
0.45	GO:0044458	motile cilium assembly
0.45	GO:1902017	regulation of cilium assembly
0.45	GO:0001947	heart looping
0.44	GO:0009880	embryonic pattern specification
0.44	GO:0009953	dorsal/ventral pattern formation
0.34	GO:0006351	transcription, DNA-templated

0.58	GO:0043565	sequence-specific DNA binding
0.37	GO:0008289	lipid binding
0.34	GO:0004000	adenosine deaminase activity
0.33	GO:0003700	DNA binding transcription factor activity

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.34

GO:0004000

tr|T1G8J7|T1G8J7_HELRO
Histone H4
Search

tr|T1G8K1|T1G8K1_HELRO
Uncharacterized protein
Search

0.54	Inositol 1,4,5-trisphosphate receptor type 2

0.85	GO:0048016	inositol phosphate-mediated signaling
0.77	GO:0006816	calcium ion transport
0.60	GO:0098662	inorganic cation transmembrane transport
0.51	GO:0051283	negative regulation of sequestering of calcium ion
0.50	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.50	GO:0071361	cellular response to ethanol
0.49	GO:0071320	cellular response to cAMP
0.48	GO:0001666	response to hypoxia
0.45	GO:0051649	establishment of localization in cell
0.35	GO:1903779	regulation of cardiac conduction

0.85	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
0.85	GO:0070679	inositol 1,4,5 trisphosphate binding
0.50	GO:0097110	scaffold protein binding
0.45	GO:0035091	phosphatidylinositol binding
0.42	GO:0005509	calcium ion binding
0.33	GO:0051287	NAD binding
0.33	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

0.70	GO:0005783	endoplasmic reticulum
0.49	GO:0016528	sarcoplasm
0.47	GO:0043235	receptor complex
0.45	GO:0005938	cell cortex
0.45	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.44	GO:0098588	bounding membrane of organelle
0.44	GO:0031984	organelle subcompartment
0.41	GO:0005634	nucleus
0.40	GO:0005886	plasma membrane
0.35	GO:0031094	platelet dense tubular network

0.33

EC:1.1.1

GO:0016616

tr|T1G8K2|T1G8K2_HELRO
Uncharacterized protein
Search

0.73	GO:0071805	potassium ion transmembrane transport
0.35	GO:1900074	negative regulation of neuromuscular synaptic transmission
0.35	GO:0045433	male courtship behavior, veined wing generated song production
0.34	GO:0034465	response to carbon monoxide
0.34	GO:0060083	smooth muscle contraction involved in micturition
0.34	GO:0045794	negative regulation of cell volume
0.34	GO:0008582	regulation of synaptic growth at neuromuscular junction
0.34	GO:0048512	circadian behavior
0.34	GO:0030007	cellular potassium ion homeostasis
0.34	GO:0051592	response to calcium ion

0.85	GO:0060072	large conductance calcium-activated potassium channel activity
0.74	GO:0005249	voltage-gated potassium channel activity
0.34	GO:0004674	protein serine/threonine kinase activity
0.33	GO:0005515	protein binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0046872	metal ion binding

0.74	GO:0008076	voltage-gated potassium channel complex
0.34	GO:0043025	neuronal cell body
0.34	GO:0005901	caveola
0.34	GO:0043005	neuron projection
0.34	GO:0016324	apical plasma membrane

0.34

GO:0004674

tr|T1G8K3|T1G8K3_HELRO
Uncharacterized protein
Search

0.11	serine/threonine-protein kinase Sgk1-like

0.63	GO:0006468	protein phosphorylation
0.42	GO:0018209	peptidyl-serine modification
0.41	GO:0035556	intracellular signal transduction
0.41	GO:1904508	regulation of protein localization to basolateral plasma membrane
0.40	GO:0048382	mesendoderm development
0.39	GO:0002119	nematode larval development
0.38	GO:0032411	positive regulation of transporter activity
0.37	GO:0001558	regulation of cell growth
0.37	GO:0042127	regulation of cell proliferation
0.36	GO:0042981	regulation of apoptotic process

0.69	GO:0004674	protein serine/threonine kinase activity
0.61	GO:0035091	phosphatidylinositol binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0000287	magnesium ion binding
0.39	GO:0017081	chloride channel regulator activity
0.38	GO:0015459	potassium channel regulator activity
0.38	GO:0017080	sodium channel regulator activity
0.38	GO:0005246	calcium channel regulator activity

0.37	GO:0005634	nucleus
0.35	GO:0031410	cytoplasmic vesicle
0.34	GO:0000785	chromatin
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0016459	myosin complex
0.32	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.69

GO:0004674

tr|T1G8K4|T1G8K4_HELRO
Uncharacterized protein
Search

0.72	GO:0006470	protein dephosphorylation
0.48	GO:0007050	cell cycle arrest
0.34	GO:0007417	central nervous system development

0.77	GO:0004722	protein serine/threonine phosphatase activity
0.53	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding
0.32	GO:0003676	nucleic acid binding

0.43	GO:0005654	nucleoplasm
0.33	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

tr|T1G8K5|T1G8K5_HELRO
Uncharacterized protein
Search

0.12

Ahnak 1

0.73	GO:1901385	regulation of voltage-gated calcium channel activity
0.59	GO:0043484	regulation of RNA splicing
0.54	GO:0051259	protein oligomerization
0.40	GO:0055114	oxidation-reduction process

0.73	GO:0044548	S100 protein binding
0.68	GO:0045296	cadherin binding
0.64	GO:0097493	structural molecule activity conferring elasticity
0.40	GO:0016491	oxidoreductase activity
0.38	GO:0003723	RNA binding

0.71	GO:0044291	cell-cell contact zone
0.70	GO:0042383	sarcolemma
0.68	GO:0070062	extracellular exosome
0.67	GO:0045121	membrane raft
0.63	GO:0043034	costamere
0.62	GO:0015629	actin cytoskeleton
0.60	GO:0005829	cytosol
0.49	GO:0019013	viral nucleocapsid
0.48	GO:0005634	nucleus
0.43	GO:0005765	lysosomal membrane

0.40

GO:0016491

tr|T1G8K6|T1G8K6_HELRO
Uncharacterized protein
Search

tr|T1G8K7|T1G8K7_HELRO
Uncharacterized protein
Search

tr|T1G8K8|T1G8K8_HELRO
Uncharacterized protein
Search

tr|T1G8K9|T1G8K9_HELRO
Uncharacterized protein
Search

TBC1D13

0.57	TBC1 domain family member 13

0.69	GO:0043547	positive regulation of GTPase activity
0.63	GO:0006886	intracellular protein transport
0.62	GO:0031338	regulation of vesicle fusion
0.52	GO:0006451	translational readthrough
0.38	GO:1902017	regulation of cilium assembly

0.73	GO:0017137	Rab GTPase binding
0.70	GO:0005096	GTPase activator activity
0.58	GO:0061770	translation elongation factor binding
0.36	GO:0046872	metal ion binding
0.35	GO:0003735	structural constituent of ribosome
0.34	GO:0016787	hydrolase activity
0.34	GO:0003676	nucleic acid binding

0.59	GO:0005829	cytosol
0.52	GO:0012505	endomembrane system
0.37	GO:0005761	mitochondrial ribosome
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0016787

tr|T1G8L1|T1G8L1_HELRO
Uncharacterized protein
Search

WDR47

0.55	WD repeat-containing protein 47

0.78	GO:0007219	Notch signaling pathway
0.68	GO:0045892	negative regulation of transcription, DNA-templated
0.50	GO:0055085	transmembrane transport
0.39	GO:0006438	valyl-tRNA aminoacylation
0.38	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.38	GO:0106074	aminoacyl-tRNA metabolism involved in translational fidelity

0.74	GO:0003682	chromatin binding
0.60	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.51	GO:0032559	adenyl ribonucleotide binding
0.50	GO:0008144	drug binding
0.50	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.39	GO:0004832	valine-tRNA ligase activity
0.38	GO:0002161	aminoacyl-tRNA editing activity
0.34	GO:0003676	nucleic acid binding

0.30

GO:0016020

membrane

0.39	EC:3.1.26.4	GO:0004523
0.39	KEGG:R03665	GO:0004832

tr|T1G8L2|T1G8L2_HELRO
Uncharacterized protein
Search

0.57	Glucose-dependent insulinotropic receptor

0.38	GO:0006887	exocytosis
0.35	GO:0048278	vesicle docking
0.34	GO:0051601	exocyst localization
0.34	GO:0009967	positive regulation of signal transduction
0.34	GO:0007165	signal transduction
0.34	GO:0090407	organophosphate biosynthetic process
0.33	GO:0032501	multicellular organismal process
0.33	GO:0016540	protein autoprocessing
0.33	GO:0018107	peptidyl-threonine phosphorylation
0.33	GO:0009187	cyclic nucleotide metabolic process

0.35	GO:0005070	SH3/SH2 adaptor activity
0.34	GO:0005080	protein kinase C binding
0.34	GO:0000149	SNARE binding
0.33	GO:0004683	calmodulin-dependent protein kinase activity
0.33	GO:0016849	phosphorus-oxygen lyase activity
0.33	GO:0003951	NAD+ kinase activity
0.33	GO:0004609	phosphatidylserine decarboxylase activity
0.33	GO:0005516	calmodulin binding
0.33	GO:0004012	phospholipid-translocating ATPase activity
0.33	GO:0042803	protein homodimerization activity

0.37	GO:0000145	exocyst
0.35	GO:0120025	plasma membrane bounded cell projection
0.34	GO:0097458	neuron part
0.33	GO:0043227	membrane-bounded organelle
0.33	GO:0044446	intracellular organelle part
0.33	GO:0044463	cell projection part
0.33	GO:0031975	envelope
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.32	GO:1902494	catalytic complex
0.30	GO:0016021	integral component of membrane

0.33	EC:2.7.11.17	GO:0004683
0.33	KEGG:R00104	GO:0003951

tr|T1G8L3|T1G8L3_HELRO
Uncharacterized protein
Search

tr|T1G8L4|T1G8L4_HELRO
Uncharacterized protein
Search

0.27	Putative syntaxin-binding protein 2 (Fragment)

0.46

GO:0006904

vesicle docking involved in exocytosis

0.30

GO:0044425

membrane part

tr|T1G8L5|T1G8L5_HELRO
Uncharacterized protein
Search

tr|T1G8L6|T1G8L6_HELRO
Uncharacterized protein
Search

0.44	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.44	GO:1903506	regulation of nucleic acid-templated transcription
0.44	GO:0010468	regulation of gene expression

0.55

GO:0003677

DNA binding

0.61

GO:0005634

nucleus

tr|T1G8L7|T1G8L7_HELRO
Uncharacterized protein
Search

NAD4L

0.42	NADH-quinone oxidoreductase subunit NuoK

0.69	GO:0042773	ATP synthesis coupled electron transport
0.34	GO:0090305	nucleic acid phosphodiester bond hydrolysis

0.67	GO:0016651	oxidoreductase activity, acting on NAD(P)H
0.34	GO:0004519	endonuclease activity

0.58	GO:0005739	mitochondrion
0.38	GO:0070469	respiratory chain
0.38	GO:0031967	organelle envelope
0.38	GO:0031090	organelle membrane
0.37	GO:0030964	NADH dehydrogenase complex
0.35	GO:1990204	oxidoreductase complex
0.34	GO:0098796	membrane protein complex
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.67

EC:1.6

GO:0016651

tr|T1G8L8|T1G8L8_HELRO
Uncharacterized protein
Search

NUOH

0.43	NADH-quinone oxidoreductase subunit NuoH

0.53

GO:0055114

oxidation-reduction process

0.68

GO:0016655

oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor

0.56

GO:0005886

plasma membrane

0.68

EC:1.6.5

GO:0016655

tr|T1G8L9|T1G8L9_HELRO
Uncharacterized protein
Search

tr|T1G8M1|T1G8M1_HELRO
Uncharacterized protein
Search

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression
0.52	GO:0035108	limb morphogenesis
0.51	GO:0035113	embryonic appendage morphogenesis
0.50	GO:0030324	lung development
0.49	GO:0048705	skeletal system morphogenesis
0.48	GO:0001525	angiogenesis
0.48	GO:0002009	morphogenesis of an epithelium

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.34	GO:0030274	LIM domain binding
0.33	GO:0001067	regulatory region nucleic acid binding
0.33	GO:0008134	transcription factor binding

0.61	GO:0005634	nucleus
0.34	GO:0097517	contractile actin filament bundle
0.34	GO:0042641	actomyosin
0.34	GO:0005884	actin filament
0.33	GO:0032993	protein-DNA complex
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|T1G8M2|T1G8M2_HELRO
Uncharacterized protein
Search

tr|T1G8M3|T1G8M3_HELRO
Uncharacterized protein
Search

tr|T1G8M4|T1G8M4_HELRO
Uncharacterized protein
Search

0.48	GO:0007160	cell-matrix adhesion
0.44	GO:0007186	G-protein coupled receptor signaling pathway
0.37	GO:0055085	transmembrane transport

0.44	GO:0004930	G-protein coupled receptor activity
0.44	GO:0046982	protein heterodimerization activity
0.37	GO:0022857	transmembrane transporter activity

0.30

GO:0044425

membrane part

tr|T1G8M5|T1G8M5_HELRO
Uncharacterized protein
Search

0.10	Cytochrome oxidase subunit II (Fragment)

0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0022900	electron transport chain
0.41	GO:0045333	cellular respiration
0.40	GO:0006119	oxidative phosphorylation
0.35	GO:0090305	nucleic acid phosphodiester bond hydrolysis

0.72	GO:0005507	copper ion binding
0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016675	oxidoreductase activity, acting on a heme group of donors
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity
0.35	GO:0004519	endonuclease activity
0.35	GO:0020037	heme binding
0.35	GO:0005506	iron ion binding
0.33	GO:0008137	NADH dehydrogenase (ubiquinone) activity

0.62	GO:0070469	respiratory chain
0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.43	GO:0098798	mitochondrial protein complex
0.42	GO:0070069	cytochrome complex
0.40	GO:0098796	membrane protein complex
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.65

EC:1.9

GO:0016675

tr|T1G8M6|T1G8M6_HELRO
Uncharacterized protein
Search

ATP6

0.41	ATP synthase subunit a

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.40	GO:0099132	ATP hydrolysis coupled cation transmembrane transport

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.40	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
0.40	GO:0019829	cation-transporting ATPase activity

0.72	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)
0.60	GO:0031966	mitochondrial membrane
0.60	GO:0019866	organelle inner membrane
0.37	GO:0098798	mitochondrial protein complex
0.35	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1G8M7|T1G8M7_HELRO
Uncharacterized protein
Search

tr|T1G8M8|T1G8M8_HELRO
Uncharacterized protein
Search

0.49	GO:1903506	regulation of nucleic acid-templated transcription
0.49	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.49	GO:0010468	regulation of gene expression
0.34	GO:0006351	transcription, DNA-templated
0.34	GO:0036211	protein modification process
0.34	GO:0043046	DNA methylation involved in gamete generation
0.34	GO:0071514	genetic imprinting
0.34	GO:0051569	regulation of histone H3-K4 methylation
0.34	GO:0044267	cellular protein metabolic process
0.34	GO:0048522	positive regulation of cellular process

0.51	GO:0003676	nucleic acid binding
0.46	GO:0046872	metal ion binding
0.38	GO:0003700	DNA binding transcription factor activity
0.34	GO:0008201	heparin binding
0.34	GO:0004672	protein kinase activity
0.34	GO:0003682	chromatin binding
0.33	GO:0042393	histone binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.42	GO:0005730	nucleolus
0.41	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|T1G8M9|T1G8M9_HELRO
Uncharacterized protein
Search

0.68	T-box transcription factor mls-1

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.39	GO:0042694	muscle cell fate specification
0.37	GO:0009791	post-embryonic development
0.34	GO:0035023	regulation of Rho protein signal transduction
0.33	GO:0065009	regulation of molecular function

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.34	GO:0005089	Rho guanyl-nucleotide exchange factor activity

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|T1G8N0|T1G8N0_HELRO
Uncharacterized protein
Search

PABC

0.45	Aminodeoxychorismate lyase

0.30

GO:0008152

metabolic process

0.62	GO:0016829	lyase activity
0.37	GO:0008483	transaminase activity

0.62

EC:4

GO:0016829

tr|T1G8N1|T1G8N1_HELRO
Uncharacterized protein
Search

tr|T1G8N2|T1G8N2_HELRO
Uncharacterized protein
Search

0.43	Ribosomal protein L9

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.37	GO:0045454	cell redox homeostasis
0.36	GO:0008340	determination of adult lifespan
0.35	GO:0022900	electron transport chain
0.32	GO:0006629	lipid metabolic process
0.32	GO:0006508	proteolysis

0.66	GO:0019843	rRNA binding
0.64	GO:0003735	structural constituent of ribosome
0.37	GO:0015035	protein disulfide oxidoreductase activity
0.36	GO:0009055	electron transfer activity
0.34	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors
0.34	GO:0050660	flavin adenine dinucleotide binding
0.33	GO:0004806	triglyceride lipase activity
0.33	GO:0004252	serine-type endopeptidase activity
0.33	GO:0003924	GTPase activity

0.61	GO:0005840	ribosome
0.39	GO:0044445	cytosolic part
0.36	GO:0044446	intracellular organelle part
0.33	GO:0005634	nucleus
0.33	GO:0031974	membrane-enclosed lumen
0.30	GO:0016021	integral component of membrane

0.34

EC:1.3

GO:0016627

tr|T1G8N3|T1G8N3_HELRO
Uncharacterized protein
Search

0.44	3-oxoacyl-[acyl-carrier-protein] synthase KASIII

0.70

GO:0006633

fatty acid biosynthetic process

0.79	GO:0033818	beta-ketoacyl-acyl-carrier-protein synthase III activity
0.77	GO:0004315	3-oxoacyl-[acyl-carrier-protein] synthase activity

0.30

GO:0031224

intrinsic component of membrane

0.79

EC:2.3.1.180

GO:0033818

tr|T1G8N4|T1G8N4_HELRO
Uncharacterized protein
Search

0.17	Putative 2,4-dienoyl-CoA reductase

0.53

GO:0055114

oxidation-reduction process

0.85

GO:0008670

2,4-dienoyl-CoA reductase (NADPH) activity

0.85

EC:1.3.1.34

GO:0008670

tr|T1G8N5|T1G8N5_HELRO
Uncharacterized protein
Search

0.11	MAP/microtubule affinity-regulating kinase 3-like (Fragment)

0.80	GO:0030010	establishment of cell polarity
0.75	GO:0000226	microtubule cytoskeleton organization
0.62	GO:0006468	protein phosphorylation
0.48	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity
0.48	GO:0060284	regulation of cell development
0.47	GO:0031346	positive regulation of cell projection organization
0.47	GO:0048699	generation of neurons
0.47	GO:2000026	regulation of multicellular organismal development
0.46	GO:0120035	regulation of plasma membrane bounded cell projection organization
0.46	GO:0045597	positive regulation of cell differentiation

0.69	GO:0004674	protein serine/threonine kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0008144	drug binding
0.47	GO:0045296	cadherin binding
0.41	GO:0000287	magnesium ion binding
0.41	GO:0050321	tau-protein kinase activity

0.50	GO:0097427	microtubule bundle
0.48	GO:0016328	lateral plasma membrane
0.47	GO:0005884	actin filament
0.43	GO:0005654	nucleoplasm
0.41	GO:0045172	germline ring canal
0.41	GO:0061174	type I terminal bouton
0.41	GO:0045169	fusome
0.40	GO:0031594	neuromuscular junction
0.39	GO:0016323	basolateral plasma membrane
0.38	GO:0005938	cell cortex

0.69

GO:0004674

tr|T1G8N6|T1G8N6_HELRO
Uncharacterized protein
Search

0.75	GO:0035023	regulation of Rho protein signal transduction
0.64	GO:0065009	regulation of molecular function
0.62	GO:0035556	intracellular signal transduction
0.39	GO:0030032	lamellipodium assembly
0.39	GO:1903727	positive regulation of phospholipid metabolic process
0.38	GO:0016477	cell migration
0.38	GO:0042327	positive regulation of phosphorylation

0.75	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.51	GO:0046872	metal ion binding
0.39	GO:0005154	epidermal growth factor receptor binding

0.45	GO:0005622	intracellular
0.34	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1G8N7|T1G8N7_HELRO
Uncharacterized protein
Search

0.10	Zinc finger protein ZIC 1

0.43	GO:0043009	chordate embryonic development
0.43	GO:0048598	embryonic morphogenesis
0.43	GO:0014033	neural crest cell differentiation
0.43	GO:0007417	central nervous system development
0.42	GO:0048385	regulation of retinoic acid receptor signaling pathway
0.42	GO:0060322	head development
0.42	GO:0014031	mesenchymal cell development
0.42	GO:0048864	stem cell development
0.41	GO:1904888	cranial skeletal system development
0.41	GO:0048705	skeletal system morphogenesis

0.51	GO:0003676	nucleic acid binding
0.38	GO:0003682	chromatin binding
0.36	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.35	GO:0046872	metal ion binding
0.35	GO:0004075	biotin carboxylase activity
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0097367	carbohydrate derivative binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005515	protein binding

0.48	GO:0016604	nuclear body
0.34	GO:0005669	transcription factor TFIID complex
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.35

EC:6.3.4.14

GO:0004075

tr|T1G8N8|T1G8N8_HELRO
Uncharacterized protein
Search

0.44	GO:0070896	positive regulation of transposon integration
0.44	GO:0016348	imaginal disc-derived leg joint morphogenesis
0.43	GO:0018992	germ-line sex determination
0.43	GO:0035017	cuticle pattern formation
0.43	GO:0048067	cuticle pigmentation
0.43	GO:0035316	non-sensory hair organization
0.43	GO:0008343	adult feeding behavior
0.41	GO:0000122	negative regulation of transcription by RNA polymerase II
0.40	GO:0045944	positive regulation of transcription by RNA polymerase II
0.39	GO:0007010	cytoskeleton organization

0.51	GO:0003676	nucleic acid binding
0.36	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.33	GO:0046872	metal ion binding

0.38	GO:0005634	nucleus
0.33	GO:0043233	organelle lumen
0.32	GO:0044446	intracellular organelle part
0.32	GO:0005737	cytoplasm

tr|T1G8N9|T1G8N9_HELRO
Uncharacterized protein
Search

0.92	Putative voltage-gated channel ixodes scapularis voltage-gated channel (Fragment)

0.73	GO:0071805	potassium ion transmembrane transport
0.73	GO:0034765	regulation of ion transmembrane transport
0.73	GO:0051260	protein homooligomerization
0.35	GO:0030431	sleep
0.34	GO:0006379	mRNA cleavage
0.32	GO:0006351	transcription, DNA-templated

0.78	GO:0005249	voltage-gated potassium channel activity
0.34	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.33	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.33	GO:0008270	zinc ion binding
0.32	GO:0003676	nucleic acid binding

0.78	GO:0008076	voltage-gated potassium channel complex
0.34	GO:0032809	neuronal cell body membrane
0.34	GO:0032590	dendrite membrane
0.34	GO:0030673	axolemma

0.34

EC:3.1.4.17

GO:0004114

tr|T1G8P0|T1G8P0_HELRO
Uncharacterized protein
Search

tr|T1G8P1|T1G8P1_HELRO
Uncharacterized protein
Search

tr|T1G8P2|T1G8P2_HELRO
Uncharacterized protein
Search

0.82	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient
0.73	GO:0090662	ATP hydrolysis coupled transmembrane transport
0.70	GO:0006814	sodium ion transport
0.69	GO:0006813	potassium ion transport
0.37	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.36	GO:0006885	regulation of pH
0.36	GO:0030317	flagellated sperm motility
0.35	GO:0009566	fertilization
0.35	GO:0030004	cellular monovalent inorganic cation homeostasis
0.35	GO:0007283	spermatogenesis

0.82	GO:0005391	sodium:potassium-exchanging ATPase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0046872	metal ion binding
0.34	GO:0008900	potassium:proton exchanging ATPase activity

0.34	GO:0016323	basolateral plasma membrane
0.30	GO:0016021	integral component of membrane

0.82

EC:3.6.3.9

GO:0005391

tr|T1G8P3|T1G8P3_HELRO
Uncharacterized protein
Search

tr|T1G8P4|T1G8P4_HELRO
Uncharacterized protein
Search

tr|T1G8P5|T1G8P5_HELRO
Uncharacterized protein
Search

0.37	Putative syntaxin-binding protein 2 (Fragment)

0.60

GO:0018095

protein polyglutamylation

0.47	GO:0016874	ligase activity
0.43	GO:0030554	adenyl nucleotide binding
0.43	GO:0097367	carbohydrate derivative binding
0.43	GO:0008144	drug binding
0.43	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0031224

intrinsic component of membrane

0.47

GO:0016874

tr|T1G8P6|T1G8P6_HELRO
Uncharacterized protein
Search

0.63	GO:0006468	protein phosphorylation
0.53	GO:1905564	positive regulation of vascular endothelial cell proliferation
0.52	GO:0032148	activation of protein kinase B activity
0.52	GO:0071364	cellular response to epidermal growth factor stimulus
0.52	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol
0.52	GO:0010518	positive regulation of phospholipase activity
0.51	GO:0043536	positive regulation of blood vessel endothelial cell migration
0.51	GO:1903078	positive regulation of protein localization to plasma membrane
0.51	GO:0007173	epidermal growth factor receptor signaling pathway
0.51	GO:0097191	extrinsic apoptotic signaling pathway

0.64	GO:0004672	protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0032555	purine ribonucleotide binding
0.53	GO:0016004	phospholipase activator activity
0.53	GO:0043274	phospholipase binding
0.37	GO:0005158	insulin receptor binding
0.36	GO:0019901	protein kinase binding

0.48	GO:0097458	neuron part
0.47	GO:0032279	asymmetric synapse
0.47	GO:0099572	postsynaptic specialization
0.46	GO:0042995	cell projection
0.44	GO:0031410	cytoplasmic vesicle
0.43	GO:0044297	cell body
0.40	GO:0005886	plasma membrane
0.38	GO:0005634	nucleus
0.37	GO:0005925	focal adhesion
0.35	GO:0005829	cytosol

tr|T1G8P7|T1G8P7_HELRO
Uncharacterized protein
Search

tr|T1G8P8|T1G8P8_HELRO
Uncharacterized protein
Search

0.56	GO:0045582	positive regulation of T cell differentiation
0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.48	GO:0030097	hemopoiesis
0.36	GO:0006366	transcription by RNA polymerase II
0.35	GO:1902680	positive regulation of RNA biosynthetic process
0.35	GO:0030154	cell differentiation
0.34	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.34	GO:0009887	animal organ morphogenesis

0.62	GO:0043565	sequence-specific DNA binding
0.61	GO:0008270	zinc ion binding
0.59	GO:0003700	DNA binding transcription factor activity
0.52	GO:0044212	transcription regulatory region DNA binding
0.50	GO:0003690	double-stranded DNA binding
0.37	GO:0001085	RNA polymerase II transcription factor binding
0.36	GO:0003682	chromatin binding
0.34	GO:0004435	phosphatidylinositol phospholipase C activity
0.34	GO:0046873	metal ion transmembrane transporter activity
0.33	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity

0.49	GO:0005634	nucleus
0.36	GO:0005667	transcription factor complex
0.33	GO:0034708	methyltransferase complex
0.32	GO:0043233	organelle lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.34	EC:3.1.4.11	GO:0004435
0.34	KEGG:R03435	GO:0004435

tr|T1G8P9|T1G8P9_HELRO
Uncharacterized protein
Search

tr|T1G8Q0|T1G8Q0_HELRO
Uncharacterized protein
Search

tr|T1G8Q1|T1G8Q1_HELRO
Uncharacterized protein
Search

0.80	GO:0000266	mitochondrial fission
0.80	GO:0016559	peroxisome fission
0.50	GO:0090141	positive regulation of mitochondrial fission
0.49	GO:0003374	dynamin family protein polymerization involved in mitochondrial fission
0.48	GO:0051646	mitochondrion localization
0.46	GO:0070266	necroptotic process
0.46	GO:1900063	regulation of peroxisome organization
0.45	GO:0043653	mitochondrial fragmentation involved in apoptotic process
0.45	GO:0001836	release of cytochrome c from mitochondria
0.45	GO:0090200	positive regulation of release of cytochrome c from mitochondria

0.67	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.45	GO:0030742	GTP-dependent protein binding
0.43	GO:0017137	Rab GTPase binding
0.42	GO:0042803	protein homodimerization activity
0.42	GO:0031625	ubiquitin protein ligase binding
0.40	GO:0008017	microtubule binding
0.34	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.34	GO:0000987	proximal promoter sequence-specific DNA binding
0.34	GO:0032947	protein complex scaffold activity

0.46	GO:0099073	mitochondrion-derived vesicle
0.44	GO:0005777	peroxisome
0.43	GO:0005903	brush border
0.43	GO:0098805	whole membrane
0.43	GO:0098588	bounding membrane of organelle
0.42	GO:0044430	cytoskeletal part
0.42	GO:0048471	perinuclear region of cytoplasm
0.41	GO:0012505	endomembrane system
0.41	GO:0015630	microtubule cytoskeleton
0.41	GO:0005829	cytosol

tr|T1G8Q2|T1G8Q2_HELRO
Uncharacterized protein
Search

tr|T1G8Q4|T1G8Q4_HELRO
Uncharacterized protein
Search

0.12	Calmodulin (Fragment)

0.46	GO:1990954	establishment of protein localization to meiotic spindle pole body
0.44	GO:0031322	ascospore-type prospore-specific spindle pole body remodeling
0.43	GO:0090307	mitotic spindle assembly
0.41	GO:0043248	proteasome assembly
0.39	GO:0055085	transmembrane transport
0.36	GO:0043401	steroid hormone mediated signaling pathway
0.34	GO:0006351	transcription, DNA-templated
0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.70	GO:0005509	calcium ion binding
0.41	GO:0032947	protein complex scaffold activity
0.38	GO:0070855	myosin VI head/neck binding
0.36	GO:0016972	thiol oxidase activity
0.36	GO:0003707	steroid hormone receptor activity
0.34	GO:0043565	sequence-specific DNA binding
0.34	GO:0008270	zinc ion binding
0.34	GO:0003700	DNA binding transcription factor activity

0.45	GO:0035840	old growing cell tip
0.45	GO:0035841	new growing cell tip
0.45	GO:0005634	nucleus
0.44	GO:0035974	meiotic spindle pole body
0.44	GO:0000935	division septum
0.43	GO:0044732	mitotic spindle pole body
0.43	GO:0043332	mating projection tip
0.38	GO:0031476	myosin VI complex
0.38	GO:0070865	investment cone
0.33	GO:0005737	cytoplasm

0.36

EC:1.8.3.2

GO:0016972

tr|T1G8Q5|T1G8Q5_HELRO
Uncharacterized protein
Search

tr|T1G8Q6|T1G8Q6_HELRO
Uncharacterized protein
Search

tr|T1G8Q7|T1G8Q7_HELRO
Uncharacterized protein
Search

0.51	Ryanodine receptor 3 (Fragment)

0.84	GO:0051209	release of sequestered calcium ion into cytosol
0.38	GO:0051481	negative regulation of cytosolic calcium ion concentration
0.37	GO:0071286	cellular response to magnesium ion
0.37	GO:0071313	cellular response to caffeine
0.37	GO:0071318	cellular response to ATP
0.37	GO:0006936	muscle contraction
0.36	GO:0071277	cellular response to calcium ion
0.36	GO:0051289	protein homotetramerization
0.34	GO:1903779	regulation of cardiac conduction

0.85	GO:0005219	ryanodine-sensitive calcium-release channel activity
0.57	GO:0005509	calcium ion binding
0.38	GO:0048763	calcium-induced calcium release activity
0.35	GO:0005516	calmodulin binding
0.33	GO:0042802	identical protein binding
0.32	GO:0003676	nucleic acid binding

0.38	GO:0033017	sarcoplasmic reticulum membrane
0.37	GO:0030314	junctional membrane complex
0.36	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1G8Q8|T1G8Q8_HELRO
Uncharacterized protein
Search

0.54	GO:0034220	ion transmembrane transport
0.48	GO:0071804	cellular potassium ion transport
0.45	GO:0034765	regulation of ion transmembrane transport
0.44	GO:0007601	visual perception
0.42	GO:0035845	photoreceptor cell outer segment organization
0.41	GO:0050962	detection of light stimulus involved in sensory perception
0.41	GO:0042391	regulation of membrane potential
0.41	GO:0001895	retina homeostasis
0.40	GO:0009584	detection of visible light
0.40	GO:0007602	phototransduction

0.61	GO:0005216	ion channel activity
0.52	GO:0022836	gated channel activity
0.48	GO:0015079	potassium ion transmembrane transporter activity
0.41	GO:0030553	cGMP binding
0.33	GO:0003777	microtubule motor activity
0.33	GO:0008017	microtubule binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.42	GO:0017071	intracellular cyclic nucleotide activated cation channel complex
0.41	GO:0001750	photoreceptor outer segment
0.39	GO:0005887	integral component of plasma membrane
0.37	GO:0043195	terminal bouton
0.32	GO:0005622	intracellular

tr|T1G8Q9|T1G8Q9_HELRO
Uncharacterized protein
Search

0.90	HBN-paired class homeobox protein (Fragment)

0.70	GO:0043010	camera-type eye development
0.67	GO:0007601	visual perception
0.67	GO:0006366	transcription by RNA polymerase II
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.44	GO:1902680	positive regulation of RNA biosynthetic process
0.39	GO:0021854	hypothalamus development
0.39	GO:0060173	limb development
0.38	GO:0007389	pattern specification process

0.59	GO:0043565	sequence-specific DNA binding
0.56	GO:0003700	DNA binding transcription factor activity
0.46	GO:0001012	RNA polymerase II regulatory region DNA binding
0.44	GO:0003690	double-stranded DNA binding
0.35	GO:0019905	syntaxin binding
0.34	GO:0035299	inositol pentakisphosphate 2-kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.34	EC:2.7.1.158	GO:0035299
0.34	KEGG:R05202	GO:0035299

tr|T1G8R0|T1G8R0_HELRO
Uncharacterized protein
Search

0.68	GO:0006397	mRNA processing
0.39	GO:0008380	RNA splicing
0.37	GO:0006915	apoptotic process
0.35	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.34	GO:0032988	ribonucleoprotein complex disassembly

0.58	GO:0003723	RNA binding
0.32	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.36	GO:0031974	membrane-enclosed lumen
0.36	GO:0030529	intracellular ribonucleoprotein complex
0.36	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

tr|T1G8R1|T1G8R1_HELRO
Uncharacterized protein
Search

0.13	NADH dehydrogenase subunit 5 (Fragment)

0.68	GO:0042773	ATP synthesis coupled electron transport
0.45	GO:0090305	nucleic acid phosphodiester bond hydrolysis

0.68	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.46	GO:0004519	endonuclease activity

0.54	GO:0005739	mitochondrion
0.30	GO:0044425	membrane part

0.68

GO:0008137

tr|T1G8R2|T1G8R2_HELRO
Uncharacterized protein
Search

0.77	GO:0043065	positive regulation of apoptotic process
0.52	GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand
0.51	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage
0.49	GO:0002352	B cell negative selection
0.49	GO:0044346	fibroblast apoptotic process
0.49	GO:0048597	post-embryonic camera-type eye morphogenesis
0.48	GO:0010046	response to mycotoxin
0.48	GO:0070242	thymocyte apoptotic process
0.48	GO:1902262	apoptotic process involved in blood vessel morphogenesis
0.48	GO:0001783	B cell apoptotic process

0.47	GO:0042803	protein homodimerization activity
0.46	GO:0046982	protein heterodimerization activity
0.46	GO:0044325	ion channel binding

0.49	GO:0097145	BAK complex
0.48	GO:0005741	mitochondrial outer membrane
0.44	GO:0032592	integral component of mitochondrial membrane
0.44	GO:0046930	pore complex
0.42	GO:0005783	endoplasmic reticulum
0.41	GO:0005829	cytosol

tr|T1G8R3|T1G8R3_HELRO
Uncharacterized protein
Search

0.61	GO:0006508	proteolysis
0.48	GO:0032804	negative regulation of low-density lipoprotein particle receptor catabolic process
0.48	GO:0032902	nerve growth factor production
0.48	GO:0032911	negative regulation of transforming growth factor beta1 production
0.47	GO:0051604	protein maturation
0.47	GO:0045714	regulation of low-density lipoprotein particle receptor biosynthetic process
0.46	GO:0048240	sperm capacitation
0.46	GO:0007340	acrosome reaction
0.46	GO:0007339	binding of sperm to zona pellucida
0.44	GO:0008283	cell proliferation

0.69	GO:0004252	serine-type endopeptidase activity
0.47	GO:0048406	nerve growth factor binding
0.45	GO:0002020	protease binding
0.44	GO:0042277	peptide binding
0.44	GO:0004867	serine-type endopeptidase inhibitor activity
0.38	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0097367	carbohydrate derivative binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.46	GO:0031410	cytoplasmic vesicle
0.46	GO:0098805	whole membrane
0.46	GO:0098588	bounding membrane of organelle
0.44	GO:0012505	endomembrane system
0.44	GO:0097223	sperm part
0.43	GO:0009986	cell surface
0.43	GO:0012506	vesicle membrane
0.41	GO:0044446	intracellular organelle part
0.38	GO:0043231	intracellular membrane-bounded organelle
0.35	GO:0070062	extracellular exosome

0.69

GO:0004252

tr|T1G8R4|T1G8R4_HELRO
Uncharacterized protein
Search

NAD6

0.40	NADH-ubiquinone oxidoreductase chain 6

0.52

GO:0055114

oxidation-reduction process

0.68

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.59	GO:0005739	mitochondrion
0.34	GO:0070469	respiratory chain
0.34	GO:0031967	organelle envelope
0.34	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0008137

tr|T1G8R5|T1G8R5_HELRO
Uncharacterized protein
Search

0.11	GATA-binding protein 3 (Fragment)

0.73	GO:0045582	positive regulation of T cell differentiation
0.57	GO:0006355	regulation of transcription, DNA-templated
0.55	GO:2000611	positive regulation of thyroid hormone generation
0.54	GO:2000667	positive regulation of interleukin-13 secretion
0.54	GO:2000683	regulation of cellular response to X-ray
0.54	GO:2000664	positive regulation of interleukin-5 secretion
0.54	GO:0033600	negative regulation of mammary gland epithelial cell proliferation
0.53	GO:0060231	mesenchymal to epithelial transition
0.53	GO:0035457	cellular response to interferon-alpha
0.53	GO:2000679	positive regulation of transcription regulatory region DNA binding

0.66	GO:0000976	transcription regulatory region sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.53	GO:0071837	HMG box domain binding
0.50	GO:0001012	RNA polymerase II regulatory region DNA binding
0.50	GO:0005134	interleukin-2 receptor binding
0.50	GO:0001047	core promoter binding
0.49	GO:0003713	transcription coactivator activity
0.48	GO:0035326	enhancer binding
0.48	GO:0008134	transcription factor binding

0.55	GO:0005634	nucleus
0.46	GO:0000785	chromatin
0.44	GO:0070013	intracellular organelle lumen
0.42	GO:0005667	transcription factor complex
0.30	GO:0044425	membrane part

tr|T1G8R6|T1G8R6_HELRO
Uncharacterized protein
Search

0.58	Ribosomal protein L22

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.34	GO:0006056	mannoprotein metabolic process
0.33	GO:0036211	protein modification process
0.33	GO:0097502	mannosylation
0.33	GO:0043413	macromolecule glycosylation
0.33	GO:0042546	cell wall biogenesis
0.33	GO:0044036	cell wall macromolecule metabolic process

0.64	GO:0003735	structural constituent of ribosome
0.38	GO:0003723	RNA binding
0.34	GO:0004674	protein serine/threonine kinase activity
0.33	GO:0000030	mannosyltransferase activity
0.32	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005840	ribosome
0.41	GO:0044445	cytosolic part
0.38	GO:0044446	intracellular organelle part
0.34	GO:0005844	polysome
0.34	GO:0055044	symplast
0.34	GO:0005911	cell-cell junction
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0005634	nucleus
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0005886	plasma membrane

0.34

GO:0004674

tr|T1G8R7|T1G8R7_HELRO
Uncharacterized protein
Search

0.96	rRNA intron-encoded homing endonuclease (Fragment)

0.64

GO:0090305

nucleic acid phosphodiester bond hydrolysis

0.66

GO:0004519

endonuclease activity

tr|T1G8R8|T1G8R8_HELRO
Uncharacterized protein
Search

0.81	GO:0030198	extracellular matrix organization
0.72	GO:0007155	cell adhesion
0.64	GO:0016525	negative regulation of angiogenesis
0.57	GO:0006954	inflammatory response
0.41	GO:0048731	system development
0.40	GO:0043066	negative regulation of apoptotic process
0.40	GO:0002605	negative regulation of dendritic cell antigen processing and presentation
0.40	GO:0010754	negative regulation of cGMP-mediated signaling
0.40	GO:0010751	negative regulation of nitric oxide mediated signal transduction
0.39	GO:2001027	negative regulation of endothelial cell chemotaxis

0.70	GO:0005509	calcium ion binding
0.65	GO:0008201	heparin binding
0.59	GO:0050840	extracellular matrix binding
0.41	GO:0005518	collagen binding
0.40	GO:0070051	fibrinogen binding
0.39	GO:0030169	low-density lipoprotein particle binding
0.39	GO:0001968	fibronectin binding
0.39	GO:0017134	fibroblast growth factor binding
0.39	GO:0001786	phosphatidylserine binding
0.38	GO:0043395	heparan sulfate proteoglycan binding

0.74	GO:0031012	extracellular matrix
0.54	GO:0005615	extracellular space
0.41	GO:0005927	muscle tendon junction
0.39	GO:0031091	platelet alpha granule
0.38	GO:0009897	external side of plasma membrane
0.37	GO:0043234	protein complex
0.33	GO:0016529	sarcoplasmic reticulum
0.30	GO:0016021	integral component of membrane

tr|T1G8R9|T1G8R9_HELRO
Uncharacterized protein
Search

tr|T1G8S0|T1G8S0_HELRO
Uncharacterized protein
Search

tr|T1G8S1|T1G8S1_HELRO
Uncharacterized protein
Search

0.46	Calcium calmodulin-dependent protein kinase i

0.63	GO:0006468	protein phosphorylation
0.46	GO:0018210	peptidyl-threonine modification
0.46	GO:0018209	peptidyl-serine modification
0.41	GO:0040040	thermosensory behavior
0.41	GO:0032793	positive regulation of CREB transcription factor activity
0.40	GO:0035556	intracellular signal transduction
0.39	GO:0045664	regulation of neuron differentiation
0.39	GO:0048812	neuron projection morphogenesis
0.38	GO:0045944	positive regulation of transcription by RNA polymerase II
0.38	GO:0045475	locomotor rhythm

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0005516	calmodulin binding
0.34	GO:0003707	steroid hormone receptor activity
0.34	GO:0031418	L-ascorbic acid binding
0.34	GO:0008417	fucosyltransferase activity
0.34	GO:0005509	calcium ion binding
0.33	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

0.52	GO:0005954	calcium- and calmodulin-dependent protein kinase complex
0.43	GO:0012505	endomembrane system
0.39	GO:0005886	plasma membrane
0.36	GO:0005634	nucleus
0.36	GO:0005964	phosphorylase kinase complex
0.35	GO:0098588	bounding membrane of organelle
0.35	GO:0043005	neuron projection
0.35	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.34

GO:0008417

tr|T1G8S2|T1G8S2_HELRO
Uncharacterized protein
Search

tr|T1G8S3|T1G8S3_HELRO
Uncharacterized protein
Search

tr|T1G8S4|T1G8S4_HELRO
Uncharacterized protein
Search

0.70	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.36	GO:0035094	response to nicotine
0.36	GO:0007271	synaptic transmission, cholinergic
0.36	GO:0007274	neuromuscular synaptic transmission
0.33	GO:0006812	cation transport

0.74	GO:0005230	extracellular ligand-gated ion channel activity
0.72	GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential
0.69	GO:0004888	transmembrane signaling receptor activity
0.67	GO:0022835	transmitter-gated channel activity
0.66	GO:0140135	mechanosensitive cation channel activity
0.48	GO:0005509	calcium ion binding
0.36	GO:0042166	acetylcholine binding

0.69	GO:0045211	postsynaptic membrane
0.65	GO:0030054	cell junction
0.36	GO:0005892	acetylcholine-gated channel complex

tr|T1G8S5|T1G8S5_HELRO
Uncharacterized protein
Search

tr|T1G8S6|T1G8S6_HELRO
Uncharacterized protein
Search

0.61	GO:0006508	proteolysis
0.47	GO:0032902	nerve growth factor production
0.45	GO:0007354	zygotic determination of anterior/posterior axis, embryo
0.45	GO:0042445	hormone metabolic process
0.44	GO:0051604	protein maturation
0.44	GO:0007368	determination of left/right symmetry
0.42	GO:0009100	glycoprotein metabolic process
0.42	GO:1905910	negative regulation of dauer entry
0.41	GO:0070593	dendrite self-avoidance
0.41	GO:1901142	insulin metabolic process

0.69	GO:0004252	serine-type endopeptidase activity
0.47	GO:0048406	nerve growth factor binding
0.44	GO:0008201	heparin binding
0.38	GO:0005102	receptor binding
0.34	GO:0008376	acetylgalactosaminyltransferase activity
0.32	GO:0016301	kinase activity
0.32	GO:0046872	metal ion binding

0.42	GO:0009986	cell surface
0.42	GO:0031012	extracellular matrix
0.42	GO:0005615	extracellular space
0.39	GO:0043025	neuronal cell body
0.34	GO:0030176	integral component of endoplasmic reticulum membrane
0.34	GO:0032580	Golgi cisterna membrane

0.69

GO:0004252

tr|T1G8S7|T1G8S7_HELRO
Uncharacterized protein
Search

0.38	GO:0031053	primary miRNA processing
0.32	GO:0055085	transmembrane transport

0.50	GO:0003676	nucleic acid binding
0.33	GO:0005515	protein binding
0.33	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.36	GO:0005654	nucleoplasm
0.33	GO:0043234	protein complex
0.30	GO:0016020	membrane

tr|T1G8S8|T1G8S8_HELRO
Uncharacterized protein
Search

tr|T1G8S9|T1G8S9_HELRO
Uncharacterized protein
Search

tr|T1G8T0|T1G8T0_HELRO
Uncharacterized protein
Search

0.29	ATP-dependent DNA helicase

0.78	GO:0000723	telomere maintenance
0.69	GO:0032392	DNA geometric change
0.65	GO:0006310	DNA recombination
0.64	GO:0006281	DNA repair
0.39	GO:0006508	proteolysis
0.33	GO:0006233	dTDP biosynthetic process
0.33	GO:0044257	cellular protein catabolic process
0.33	GO:0046939	nucleotide phosphorylation
0.32	GO:0055114	oxidation-reduction process

0.70	GO:0003678	DNA helicase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0008234	cysteine-type peptidase activity
0.34	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.33	GO:0004798	thymidylate kinase activity
0.33	GO:0070003	threonine-type peptidase activity
0.33	GO:0004175	endopeptidase activity

0.33	GO:0005839	proteasome core complex
0.30	GO:0016020	membrane

0.42

GO:0008234

tr|T1G8T1|T1G8T1_HELRO
Uncharacterized protein
Search

0.73	GO:0007015	actin filament organization
0.41	GO:0043547	positive regulation of GTPase activity
0.38	GO:0007165	signal transduction
0.37	GO:0007155	cell adhesion
0.33	GO:0046328	regulation of JNK cascade
0.33	GO:0030336	negative regulation of cell migration
0.33	GO:0006915	apoptotic process

0.41	GO:0005096	GTPase activator activity
0.35	GO:0003676	nucleic acid binding
0.34	GO:0048365	Rac GTPase binding

0.37	GO:0005654	nucleoplasm
0.31	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1G8T2|T1G8T2_HELRO
Uncharacterized protein
Search

0.48	Intron-encoded LAGLIDADG endonuclease

0.55	GO:0009060	aerobic respiration
0.55	GO:0006119	oxidative phosphorylation
0.55	GO:1902600	hydrogen ion transmembrane transport
0.53	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.53	GO:0022900	electron transport chain
0.36	GO:0034337	RNA folding
0.36	GO:0000376	RNA splicing, via transesterification reactions with guanosine as nucleophile
0.35	GO:0006314	intron homing

0.56	GO:0015002	heme-copper terminal oxidase activity
0.56	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.55	GO:0020037	heme binding
0.55	GO:0015078	hydrogen ion transmembrane transporter activity
0.55	GO:0005506	iron ion binding
0.55	GO:0004519	endonuclease activity
0.54	GO:0009055	electron transfer activity
0.34	GO:0004536	deoxyribonuclease activity
0.33	GO:0003723	RNA binding
0.33	GO:0003677	DNA binding

0.58	GO:0005739	mitochondrion
0.54	GO:0070469	respiratory chain
0.54	GO:0019866	organelle inner membrane
0.38	GO:0070069	cytochrome complex
0.36	GO:0098796	membrane protein complex
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.56

EC:1.9.3

GO:0016676

tr|T1G8T3|T1G8T3_HELRO
Uncharacterized protein
Search

FKH

0.52	Fork head domain protein (Fragment)

0.57	GO:0006355	regulation of transcription, DNA-templated
0.47	GO:0009653	anatomical structure morphogenesis
0.45	GO:0009888	tissue development
0.45	GO:0030154	cell differentiation
0.44	GO:0003002	regionalization
0.44	GO:0009792	embryo development ending in birth or egg hatching
0.43	GO:0000578	embryonic axis specification
0.43	GO:0006351	transcription, DNA-templated
0.40	GO:1903507	negative regulation of nucleic acid-templated transcription
0.40	GO:0007399	nervous system development

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.38	GO:0008301	DNA binding, bending
0.38	GO:0001012	RNA polymerase II regulatory region DNA binding
0.37	GO:0003690	double-stranded DNA binding
0.34	GO:0001106	RNA polymerase II transcription corepressor activity

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|T1G8T4|T1G8T4_HELRO
Uncharacterized protein
Search

0.56	Putative syntaxin-binding protein 2 (Fragment)

0.30

GO:0044425

membrane part

tr|T1G8T5|T1G8T5_HELRO
Uncharacterized protein
Search

tr|T1G8T6|T1G8T6_HELRO
Uncharacterized protein
Search

0.54	GO:0034220	ion transmembrane transport
0.48	GO:0071804	cellular potassium ion transport
0.45	GO:0007601	visual perception
0.44	GO:0034765	regulation of ion transmembrane transport
0.42	GO:0035845	photoreceptor cell outer segment organization
0.42	GO:0050962	detection of light stimulus involved in sensory perception
0.42	GO:0001895	retina homeostasis
0.41	GO:0042391	regulation of membrane potential
0.40	GO:0009584	detection of visible light
0.40	GO:0007602	phototransduction

0.61	GO:0005216	ion channel activity
0.52	GO:0022836	gated channel activity
0.48	GO:0015079	potassium ion transmembrane transporter activity
0.41	GO:0030553	cGMP binding
0.34	GO:0005085	guanyl-nucleotide exchange factor activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0003777	microtubule motor activity
0.33	GO:0008017	microtubule binding

0.42	GO:0017071	intracellular cyclic nucleotide activated cation channel complex
0.41	GO:0001750	photoreceptor outer segment
0.39	GO:0005887	integral component of plasma membrane
0.37	GO:0043195	terminal bouton
0.33	GO:0005622	intracellular

tr|T1G8T7|T1G8T7_HELRO
Uncharacterized protein
Search

0.55	GO:0055085	transmembrane transport
0.54	GO:0006811	ion transport
0.43	GO:0071702	organic substance transport
0.42	GO:0010876	lipid localization
0.37	GO:1901998	toxin transport
0.35	GO:0070327	thyroid hormone transport
0.35	GO:0042886	amide transport
0.34	GO:0007588	excretion
0.33	GO:0001889	liver development

0.56	GO:0005215	transporter activity
0.35	GO:0008270	zinc ion binding
0.33	GO:0030246	carbohydrate binding

0.52	GO:0005886	plasma membrane
0.33	GO:0045177	apical part of cell
0.30	GO:0016021	integral component of membrane

tr|T1G8T8|T1G8T8_HELRO
Uncharacterized protein
Search

tr|T1G8T9|T1G8T9_HELRO
Uncharacterized protein
Search

0.10	Krueppel-like factor 4

0.53	GO:1904998	negative regulation of leukocyte adhesion to arterial endothelial cell
0.53	GO:2000342	negative regulation of chemokine (C-X-C motif) ligand 2 production
0.52	GO:0046985	positive regulation of hemoglobin biosynthetic process
0.52	GO:0045415	negative regulation of interleukin-8 biosynthetic process
0.52	GO:0071499	cellular response to laminar fluid shear stress
0.51	GO:0061614	pri-miRNA transcription by RNA polymerase II
0.51	GO:0034115	negative regulation of heterotypic cell-cell adhesion
0.51	GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis
0.51	GO:0031077	post-embryonic camera-type eye development
0.51	GO:0035166	post-embryonic hemopoiesis

0.51	GO:0003676	nucleic acid binding
0.50	GO:0001010	transcription factor activity, sequence-specific DNA binding transcription factor recruiting
0.50	GO:1990841	promoter-specific chromatin binding
0.49	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.49	GO:0001085	RNA polymerase II transcription factor binding
0.48	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.48	GO:0008013	beta-catenin binding
0.38	GO:0001221	transcription cofactor binding
0.37	GO:0035014	phosphatidylinositol 3-kinase regulator activity
0.37	GO:0042826	histone deacetylase binding

0.48	GO:0005719	nuclear euchromatin
0.45	GO:0044798	nuclear transcription factor complex
0.44	GO:0005654	nucleoplasm
0.36	GO:0005737	cytoplasm

tr|T1G8U0|T1G8U0_HELRO
Uncharacterized protein
Search

0.40	Zinc finger protein 3

0.40	GO:0043007	maintenance of rDNA
0.40	GO:0006349	regulation of gene expression by genetic imprinting
0.40	GO:0007379	segment specification
0.39	GO:0035075	response to ecdysone
0.37	GO:0045892	negative regulation of transcription, DNA-templated
0.33	GO:0055085	transmembrane transport

0.51	GO:0003676	nucleic acid binding
0.38	GO:0003682	chromatin binding
0.33	GO:0022857	transmembrane transporter activity

0.35	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|T1G8U1|T1G8U1_HELRO
Uncharacterized protein
Search

TMEM38B-A

0.83	Trimeric intracellular cation channel type B-A

0.62	GO:0015672	monovalent inorganic cation transport
0.61	GO:0098655	cation transmembrane transport
0.39	GO:0030001	metal ion transport
0.38	GO:0098660	inorganic ion transmembrane transport
0.30	GO:0009987	cellular process

0.74	GO:0005261	cation channel activity
0.41	GO:0015079	potassium ion transmembrane transporter activity
0.41	GO:0022839	ion gated channel activity
0.40	GO:0008381	mechanosensitive ion channel activity

0.36	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1G8U2|T1G8U2_HELRO
Rab GDP dissociation inhibitor
Search

0.68	Rab GDP dissociation inhibitor

0.77	GO:0007264	small GTPase mediated signal transduction
0.74	GO:0043547	positive regulation of GTPase activity
0.65	GO:0015031	protein transport
0.36	GO:0016192	vesicle-mediated transport
0.36	GO:0006744	ubiquinone biosynthetic process
0.36	GO:0099643	signal release from synapse
0.36	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.36	GO:0032259	methylation
0.35	GO:0006836	neurotransmitter transport
0.35	GO:0001505	regulation of neurotransmitter levels

0.85	GO:0005093	Rab GDP-dissociation inhibitor activity
0.75	GO:0005096	GTPase activator activity
0.36	GO:0008425	2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity
0.34	GO:0004395	hexaprenyldihydroxybenzoate methyltransferase activity
0.34	GO:0008689	3-demethylubiquinone-9 3-O-methyltransferase activity
0.32	GO:0016491	oxidoreductase activity
0.32	GO:0046872	metal ion binding

0.48	GO:0005737	cytoplasm
0.35	GO:0098793	presynapse
0.35	GO:0097708	intracellular vesicle
0.34	GO:0012505	endomembrane system
0.34	GO:0031312	extrinsic component of organelle membrane
0.33	GO:0019866	organelle inner membrane
0.32	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.36

GO:0008425

tr|T1G8U3|T1G8U3_HELRO
Uncharacterized protein
Search

DPH7

0.89	Diphthamide biosynthesis protein 7

0.81	GO:0017182	peptidyl-diphthamide metabolic process
0.81	GO:1900247	regulation of cytoplasmic translational elongation
0.48	GO:0044249	cellular biosynthetic process

tr|T1G8U4|T1G8U4_HELRO
Sodium/nucleoside cotransporter
Search

0.82	Sodium/nucleoside cotransporter

0.79	GO:1901642	nucleoside transmembrane transport
0.40	GO:0072530	purine-containing compound transmembrane transport
0.36	GO:0015864	pyrimidine nucleoside transport
0.35	GO:0006863	purine nucleobase transport
0.35	GO:0034394	protein localization to cell surface
0.35	GO:0001895	retina homeostasis
0.35	GO:0072531	pyrimidine-containing compound transmembrane transport
0.34	GO:0015855	pyrimidine nucleobase transport

0.78	GO:0005337	nucleoside transmembrane transporter activity
0.60	GO:0015370	solute:sodium symporter activity
0.35	GO:0005345	purine nucleobase transmembrane transporter activity
0.35	GO:0005350	pyrimidine nucleobase transmembrane transporter activity

0.54

GO:0005887

integral component of plasma membrane

tr|T1G8U5|T1G8U5_HELRO
Uncharacterized protein
Search

PAF1

0.85	RNA polymerase II-associated factor

0.81	GO:0006368	transcription elongation from RNA polymerase II promoter
0.74	GO:0016570	histone modification
0.42	GO:0031442	positive regulation of mRNA 3'-end processing
0.41	GO:1902808	positive regulation of cell cycle G1/S phase transition
0.41	GO:0045638	negative regulation of myeloid cell differentiation
0.41	GO:0016584	nucleosome positioning
0.41	GO:0031062	positive regulation of histone methylation
0.41	GO:0001711	endodermal cell fate commitment
0.41	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter
0.41	GO:0006513	protein monoubiquitination

0.42	GO:0000993	RNA polymerase II core binding
0.39	GO:0003682	chromatin binding
0.33	GO:0004386	helicase activity
0.33	GO:0003700	DNA binding transcription factor activity

0.82	GO:0016593	Cdc73/Paf1 complex
0.39	GO:0030054	cell junction
0.38	GO:0034464	BBSome
0.35	GO:0035327	transcriptionally active chromatin
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1G8U6|T1G8U6_HELRO
Peptidyl-prolyl cis-trans isomerase
Search

0.45	Peptidyl-prolyl cis-trans isomerase B

0.72	GO:0000413	protein peptidyl-prolyl isomerization
0.67	GO:0006457	protein folding
0.35	GO:0010555	response to mannitol
0.34	GO:0009628	response to abiotic stimulus
0.34	GO:0009735	response to cytokinin
0.34	GO:0009737	response to abscisic acid
0.34	GO:0042742	defense response to bacterium
0.34	GO:0019344	cysteine biosynthetic process
0.33	GO:0000398	mRNA splicing, via spliceosome
0.33	GO:0006979	response to oxidative stress

0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.37	GO:0003723	RNA binding
0.33	GO:0003690	double-stranded DNA binding
0.33	GO:0005515	protein binding
0.32	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups

0.40	GO:0000974	Prp19 complex
0.37	GO:0031011	Ino80 complex
0.34	GO:0005788	endoplasmic reticulum lumen
0.34	GO:0031977	thylakoid lumen
0.34	GO:0071011	precatalytic spliceosome
0.34	GO:0048046	apoplast
0.34	GO:0009941	chloroplast envelope
0.34	GO:0071013	catalytic step 2 spliceosome
0.34	GO:0009570	chloroplast stroma
0.34	GO:0022626	cytosolic ribosome

0.72

EC:5.2.1.8

GO:0003755

tr|T1G8U7|T1G8U7_HELRO
Uncharacterized protein
Search

ODC1

0.49	Ornithine decarboxylase

0.72	GO:0006596	polyamine biosynthetic process
0.55	GO:0009445	putrescine metabolic process
0.52	GO:0006591	ornithine metabolic process
0.52	GO:0001822	kidney development
0.51	GO:0042176	regulation of protein catabolic process
0.51	GO:0008284	positive regulation of cell proliferation
0.50	GO:0009615	response to virus
0.44	GO:0042462	eye photoreceptor cell development
0.35	GO:1902269	positive regulation of polyamine transmembrane transport
0.35	GO:0006521	regulation of cellular amino acid metabolic process

0.58	GO:0004586	ornithine decarboxylase activity
0.50	GO:0042803	protein homodimerization activity
0.35	GO:0042978	ornithine decarboxylase activator activity

0.47	GO:0005829	cytosol
0.37	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0005634	nucleus

0.58	EC:4.1.1.17	GO:0004586
0.58	KEGG:R00670	GO:0004586

tr|T1G8U8|T1G8U8_HELRO
Uncharacterized protein
Search

0.81	Alpha-actinin, sarcomeric

0.39	GO:0051017	actin filament bundle assembly
0.39	GO:0051764	actin crosslink formation
0.34	GO:0048741	skeletal muscle fiber development
0.34	GO:0045214	sarcomere organization
0.33	GO:0007186	G-protein coupled receptor signaling pathway

0.74	GO:0003779	actin binding
0.69	GO:0005509	calcium ion binding
0.38	GO:0032403	protein complex binding
0.35	GO:0017166	vinculin binding
0.35	GO:0051393	alpha-actinin binding
0.34	GO:0042803	protein homodimerization activity
0.34	GO:0004930	G-protein coupled receptor activity

0.35	GO:0030486	smooth muscle dense body
0.35	GO:0090637	inner dense plaque of desmosome
0.35	GO:0090636	outer dense plaque of desmosome
0.35	GO:1990357	terminal web
0.35	GO:0005915	zonula adherens
0.35	GO:0097433	dense body
0.34	GO:0016328	lateral plasma membrane
0.34	GO:0097517	contractile actin filament bundle
0.34	GO:0042641	actomyosin
0.34	GO:0042383	sarcolemma

tr|T1G8U9|T1G8U9_HELRO
Uncharacterized protein
Search

0.40	Inorganic pyrophosphatase

0.55	GO:0006796	phosphate-containing compound metabolic process
0.45	GO:0035206	regulation of hemocyte proliferation
0.45	GO:0035076	ecdysone receptor-mediated signaling pathway
0.45	GO:0042766	nucleosome mobilization
0.44	GO:0045747	positive regulation of Notch signaling pathway
0.37	GO:0006351	transcription, DNA-templated
0.37	GO:0007020	microtubule nucleation
0.33	GO:0016569	covalent chromatin modification
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:1903506	regulation of nucleic acid-templated transcription

0.78	GO:0004427	inorganic diphosphatase activity
0.64	GO:0000287	magnesium ion binding
0.37	GO:0043015	gamma-tubulin binding
0.35	GO:0070615	nucleosome-dependent ATPase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003676	nucleic acid binding

0.49	GO:0005737	cytoplasm
0.44	GO:0016589	NURF complex
0.37	GO:0000922	spindle pole
0.36	GO:0005815	microtubule organizing center

0.78	EC:3.6.1.1	GO:0004427
0.78	KEGG:R00004	GO:0004427

tr|T1G8V0|T1G8V0_HELRO
Tubulin beta chain
Search

0.49	Tubulin beta chain

0.72	GO:0007017	microtubule-based process
0.71	GO:0007010	cytoskeleton organization
0.41	GO:0007435	salivary gland morphogenesis
0.35	GO:1902669	positive regulation of axon guidance
0.34	GO:0001764	neuron migration

0.77	GO:0005200	structural constituent of cytoskeleton
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0046982	protein heterodimerization activity

0.73	GO:0005874	microtubule
0.46	GO:0005737	cytoplasm
0.35	GO:0044441	ciliary part
0.30	GO:0031224	intrinsic component of membrane

tr|T1G8V1|T1G8V1_HELRO
Uncharacterized protein
Search

0.37	GO:0055085	transmembrane transport
0.35	GO:0018996	molting cycle, collagen and cuticulin-based cuticle
0.35	GO:0006672	ceramide metabolic process
0.33	GO:0016485	protein processing
0.32	GO:0006518	peptide metabolic process
0.32	GO:0022900	electron transport chain
0.32	GO:0009058	biosynthetic process

0.38	GO:0022857	transmembrane transporter activity
0.34	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
0.33	GO:0004181	metallocarboxypeptidase activity
0.33	GO:0004185	serine-type carboxypeptidase activity
0.33	GO:0031177	phosphopantetheine binding
0.33	GO:0016788	hydrolase activity, acting on ester bonds
0.32	GO:0008270	zinc ion binding
0.32	GO:0020037	heme binding
0.32	GO:0016740	transferase activity
0.32	GO:0009055	electron transfer activity

0.33	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:3.5.1

GO:0016811

tr|T1G8V2|T1G8V2_HELRO
Uncharacterized protein
Search

0.69	GO:0016024	CDP-diacylglycerol biosynthetic process
0.47	GO:0070970	interleukin-2 secretion
0.47	GO:0070236	negative regulation of activation-induced cell death of T cells
0.46	GO:0055089	fatty acid homeostasis
0.46	GO:0055091	phospholipid homeostasis
0.46	GO:0042104	positive regulation of activated T cell proliferation
0.45	GO:0019432	triglyceride biosynthetic process
0.45	GO:0040018	positive regulation of multicellular organism growth
0.44	GO:0009749	response to glucose
0.44	GO:0050707	regulation of cytokine secretion

0.75	GO:0004366	glycerol-3-phosphate O-acyltransferase activity
0.66	GO:0102420	sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity
0.33	GO:0016849	phosphorus-oxygen lyase activity

0.54	GO:0005741	mitochondrial outer membrane
0.50	GO:0005886	plasma membrane
0.39	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.75

EC:2.3.1.15

GO:0004366

tr|T1G8V3|T1G8V3_HELRO
Uncharacterized protein
Search

0.11	Dual specificity protein phosphatase, putative

0.72	GO:0006470	protein dephosphorylation
0.67	GO:0000188	inactivation of MAPK activity
0.44	GO:0072327	vulval cell fate specification
0.43	GO:0040026	positive regulation of vulval development
0.42	GO:0042659	regulation of cell fate specification
0.42	GO:0051447	negative regulation of meiotic cell cycle
0.42	GO:0048599	oocyte development
0.42	GO:0046580	negative regulation of Ras protein signal transduction
0.41	GO:0007219	Notch signaling pathway
0.40	GO:0009792	embryo development ending in birth or egg hatching

0.79	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.67	GO:0033549	MAP kinase phosphatase activity
0.55	GO:0004725	protein tyrosine phosphatase activity
0.34	GO:0005515	protein binding

0.36	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.79

GO:0008138

tr|T1G8V4|T1G8V4_HELRO
Synaptotagmin 7d
Search

SYT7

0.87	Synaptotagmin VIIb

0.76	GO:0006887	exocytosis
0.53	GO:0099643	signal release from synapse
0.53	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.52	GO:0090119	vesicle-mediated cholesterol transport
0.51	GO:1990926	short-term synaptic potentiation
0.51	GO:0017158	regulation of calcium ion-dependent exocytosis
0.50	GO:0070092	regulation of glucagon secretion
0.50	GO:0006836	neurotransmitter transport
0.50	GO:0090385	phagosome-lysosome fusion
0.50	GO:0048489	synaptic vesicle transport

0.81	GO:0005544	calcium-dependent phospholipid binding
0.49	GO:0000149	SNARE binding
0.49	GO:0001786	phosphatidylserine binding
0.48	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.46	GO:0005516	calmodulin binding
0.44	GO:0030276	clathrin binding
0.41	GO:0005509	calcium ion binding

0.51	GO:0098793	presynapse
0.49	GO:0032009	early phagosome
0.48	GO:0070382	exocytic vesicle
0.48	GO:0005764	lysosome
0.48	GO:0044306	neuron projection terminus
0.47	GO:0043025	neuronal cell body
0.46	GO:0030425	dendrite
0.46	GO:0097060	synaptic membrane
0.45	GO:0005777	peroxisome
0.43	GO:0005829	cytosol

tr|T1G8V5|T1G8V5_HELRO
Uncharacterized protein
Search

0.84	Increased Sodium Tolerance Related

0.65	GO:0015031	protein transport
0.44	GO:0032509	endosome transport via multivesicular body sorting pathway

0.42	GO:0005768	endosome
0.36	GO:0043231	intracellular membrane-bounded organelle

tr|T1G8V6|T1G8V6_HELRO
Uncharacterized protein
Search

0.60	GO:0006508	proteolysis
0.58	GO:0007229	integrin-mediated signaling pathway
0.49	GO:0022011	myelination in peripheral nervous system
0.48	GO:0008344	adult locomotory behavior
0.35	GO:2000415	positive regulation of fibronectin-dependent thymocyte migration
0.35	GO:0009405	pathogenesis
0.35	GO:0030155	regulation of cell adhesion
0.35	GO:2000309	positive regulation of tumor necrosis factor (ligand) superfamily member 11 production
0.35	GO:2000418	positive regulation of eosinophil migration
0.35	GO:0070245	positive regulation of thymocyte apoptotic process

0.70	GO:0004222	metalloendopeptidase activity
0.47	GO:0046872	metal ion binding
0.36	GO:0090729	toxin activity
0.36	GO:0050839	cell adhesion molecule binding
0.35	GO:0043015	gamma-tubulin binding
0.34	GO:0032403	protein complex binding
0.34	GO:0005102	receptor binding
0.33	GO:0016757	transferase activity, transferring glycosyl groups
0.32	GO:0003676	nucleic acid binding

0.47	GO:0030424	axon
0.35	GO:0032127	dense core granule membrane
0.35	GO:0071133	alpha9-beta1 integrin-ADAM8 complex
0.35	GO:0071065	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex
0.35	GO:0005576	extracellular region
0.35	GO:0032010	phagolysosome
0.35	GO:0070820	tertiary granule
0.35	GO:0042581	specific granule
0.35	GO:0002102	podosome
0.34	GO:0000922	spindle pole

0.70

GO:0004222

tr|T1G8V7|T1G8V7_HELRO
Uncharacterized protein
Search

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.48	GO:0042593	glucose homeostasis
0.47	GO:0007283	spermatogenesis
0.47	GO:0009267	cellular response to starvation
0.46	GO:0048785	hatching gland development
0.46	GO:0021999	neural plate anterior/posterior regionalization
0.46	GO:0048319	axial mesoderm morphogenesis
0.46	GO:0051254	positive regulation of RNA metabolic process

0.69	GO:0019904	protein domain specific binding
0.66	GO:0008134	transcription factor binding
0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.47	GO:0044212	transcription regulatory region DNA binding
0.33	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.45	GO:0015629	actin cytoskeleton
0.43	GO:0043233	organelle lumen
0.40	GO:0044446	intracellular organelle part
0.36	GO:0005902	microvillus
0.33	GO:0005829	cytosol

tr|T1G8V8|T1G8V8_HELRO
Uncharacterized protein
Search

TAF6

0.74	Transcription initiation factor TFIID subunit 6

0.80	GO:0051090	regulation of DNA binding transcription factor activity
0.68	GO:0006352	DNA-templated transcription, initiation
0.54	GO:0006413	translational initiation
0.44	GO:0045786	negative regulation of cell cycle
0.43	GO:0006366	transcription by RNA polymerase II
0.35	GO:0008285	negative regulation of cell proliferation
0.34	GO:0009301	snRNA transcription
0.34	GO:1901796	regulation of signal transduction by p53 class mediator
0.33	GO:0006354	DNA-templated transcription, elongation

0.73	GO:0046982	protein heterodimerization activity
0.54	GO:0003743	translation initiation factor activity
0.48	GO:0017162	aryl hydrocarbon receptor binding
0.39	GO:0003700	DNA binding transcription factor activity
0.38	GO:0003677	DNA binding

0.82	GO:0046695	SLIK (SAGA-like) complex
0.80	GO:0000124	SAGA complex
0.80	GO:0005669	transcription factor TFIID complex
0.47	GO:0033276	transcription factor TFTC complex
0.45	GO:0071339	MLL1 complex
0.41	GO:0005829	cytosol
0.30	GO:0016020	membrane

tr|T1G8V9|T1G8V9_HELRO
Uncharacterized protein
Search

GABARAPL2

0.97	GABA type A receptor associated protein like 2

0.77	GO:0006914	autophagy
0.48	GO:0006995	cellular response to nitrogen starvation
0.48	GO:1901799	negative regulation of proteasomal protein catabolic process
0.46	GO:0061726	mitochondrion disassembly
0.44	GO:0007033	vacuole organization
0.42	GO:0070925	organelle assembly
0.39	GO:0010940	positive regulation of necrotic cell death
0.38	GO:2000786	positive regulation of autophagosome assembly
0.38	GO:0040024	dauer larval development
0.38	GO:0050830	defense response to Gram-positive bacterium

0.46	GO:0031625	ubiquitin protein ligase binding
0.35	GO:0051117	ATPase binding
0.35	GO:0000149	SNARE binding
0.34	GO:0019786	Atg8-specific protease activity
0.34	GO:0050811	GABA receptor binding
0.34	GO:0019779	Atg8 activating enzyme activity
0.34	GO:0019776	Atg8 ligase activity
0.34	GO:0048487	beta-tubulin binding
0.33	GO:0008017	microtubule binding
0.33	GO:0004252	serine-type endopeptidase activity

0.53	GO:0000421	autophagosome membrane
0.45	GO:0000139	Golgi membrane
0.41	GO:0005829	cytosol
0.37	GO:0005741	mitochondrial outer membrane
0.36	GO:0031410	cytoplasmic vesicle
0.34	GO:0043202	lysosomal lumen
0.33	GO:0000407	phagophore assembly site
0.33	GO:0005874	microtubule
0.32	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.33

GO:0004252

tr|T1G8W0|T1G8W0_HELRO
Uncharacterized protein
Search

WARS2

0.41	Tryptophanyl-tRNA synthetase

0.78	GO:0006436	tryptophanyl-tRNA aminoacylation
0.53	GO:0001570	vasculogenesis
0.35	GO:0070127	tRNA aminoacylation for mitochondrial protein translation
0.33	GO:0006457	protein folding
0.33	GO:0050790	regulation of catalytic activity

0.79	GO:0004830	tryptophan-tRNA ligase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0000774	adenyl-nucleotide exchange factor activity
0.33	GO:0051087	chaperone binding
0.33	GO:0042803	protein homodimerization activity
0.32	GO:0046872	metal ion binding

0.49	GO:0005759	mitochondrial matrix
0.41	GO:0005886	plasma membrane
0.32	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

0.79

EC:6.1.1.2

GO:0004830

tr|T1G8W1|T1G8W1_HELRO
Uncharacterized protein
Search

SDAD1

0.88	Protein required for actin cytoskeleton organization and cell cycle progression

0.84	GO:0000055	ribosomal large subunit export from nucleus
0.76	GO:0042273	ribosomal large subunit biogenesis
0.74	GO:0030036	actin cytoskeleton organization
0.37	GO:1990830	cellular response to leukemia inhibitory factor
0.33	GO:0006260	DNA replication

0.30

GO:0003824

catalytic activity

0.49	GO:0005730	nucleolus
0.34	GO:0000808	origin recognition complex

tr|T1G8W2|T1G8W2_HELRO
Uncharacterized protein
Search

0.53	Glucose dehydrogenase [acceptor]

0.53	GO:0055114	oxidation-reduction process
0.41	GO:0019285	glycine betaine biosynthetic process from choline
0.33	GO:0042254	ribosome biogenesis
0.32	GO:0006468	protein phosphorylation
0.32	GO:0006351	transcription, DNA-templated

0.66	GO:0050660	flavin adenine dinucleotide binding
0.65	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors
0.32	GO:0004672	protein kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0008270	zinc ion binding
0.31	GO:0003677	DNA binding
0.31	GO:0016829	lyase activity

0.32	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.65

EC:1.1

GO:0016614

tr|T1G8W3|T1G8W3_HELRO
Uncharacterized protein
Search

SYN2

0.91	Synapsin III

0.82	GO:0099643	signal release from synapse
0.82	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.76	GO:0006836	neurotransmitter transport
0.72	GO:0001505	regulation of neurotransmitter levels
0.69	GO:0051649	establishment of localization in cell
0.34	GO:0051588	regulation of neurotransmitter transport
0.34	GO:0050804	modulation of chemical synaptic transmission
0.34	GO:1903530	regulation of secretion by cell
0.34	GO:0060341	regulation of cellular localization

0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0046872	metal ion binding
0.35	GO:0048306	calcium-dependent protein binding
0.33	GO:0008092	cytoskeletal protein binding
0.33	GO:0046983	protein dimerization activity

0.82	GO:0008021	synaptic vesicle
0.53	GO:0099501	exocytic vesicle membrane
0.51	GO:0014069	postsynaptic density
0.50	GO:0031201	SNARE complex
0.49	GO:0043209	myelin sheath
0.40	GO:0005886	plasma membrane
0.37	GO:0030054	cell junction
0.35	GO:0043195	terminal bouton

tr|T1G8W4|T1G8W4_HELRO
Uncharacterized protein
Search

RGS7

0.76	Regulator of G-protein signaling

0.70	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.62	GO:0035556	intracellular signal transduction
0.45	GO:0043547	positive regulation of GTPase activity
0.36	GO:0046662	regulation of oviposition
0.36	GO:0009968	negative regulation of signal transduction
0.36	GO:0007622	rhythmic behavior
0.36	GO:0007631	feeding behavior
0.35	GO:0040017	positive regulation of locomotion
0.33	GO:0006457	protein folding

0.63	GO:0004871	signal transducer activity
0.46	GO:0031681	G-protein beta-subunit binding
0.45	GO:0005096	GTPase activator activity

0.81	GO:1905360	GTPase complex
0.79	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.65	GO:0098797	plasma membrane protein complex
0.40	GO:0005829	cytosol
0.37	GO:0043005	neuron projection
0.35	GO:0036477	somatodendritic compartment
0.35	GO:0120038	plasma membrane bounded cell projection part
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

tr|T1G8W5|T1G8W5_HELRO
Ribonucleoside-diphosphate reductase
Search

RRM1

0.53	Ribonucleoside-diphosphate reductase large subunit

0.66	GO:0006260	DNA replication
0.53	GO:0055114	oxidation-reduction process
0.52	GO:0051290	protein heterotetramerization
0.47	GO:0009263	deoxyribonucleotide biosynthetic process
0.38	GO:0021846	cell proliferation in forebrain
0.37	GO:0008584	male gonad development
0.37	GO:0060041	retina development in camera-type eye
0.37	GO:0010212	response to ionizing radiation
0.36	GO:0000278	mitotic cell cycle
0.36	GO:0006206	pyrimidine nucleobase metabolic process

0.77	GO:0061731	ribonucleoside-diphosphate reductase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0097718	disordered domain specific binding
0.47	GO:0042802	identical protein binding

0.49	GO:0005971	ribonucleoside-diphosphate reductase complex
0.37	GO:0043025	neuronal cell body
0.36	GO:0005635	nuclear envelope
0.35	GO:0070062	extracellular exosome
0.35	GO:0042995	cell projection
0.30	GO:0016020	membrane

tr|T1G8W6|T1G8W6_HELRO
Adenylosuccinate synthetase
Search

0.45	Adenylosuccinate synthetase

0.75	GO:0044208	'de novo' AMP biosynthetic process
0.42	GO:0046040	IMP metabolic process
0.39	GO:0071257	cellular response to electrical stimulus
0.39	GO:0014850	response to muscle activity
0.38	GO:0006531	aspartate metabolic process
0.38	GO:0035690	cellular response to drug
0.37	GO:0042594	response to starvation
0.36	GO:0006541	glutamine metabolic process
0.34	GO:0030036	actin cytoskeleton organization
0.34	GO:0071276	cellular response to cadmium ion

0.79	GO:0004019	adenylosuccinate synthase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.61	GO:0000287	magnesium ion binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0003779	actin binding
0.37	GO:0042803	protein homodimerization activity
0.37	GO:0032403	protein complex binding
0.36	GO:0003924	GTPase activity

0.48	GO:0005737	cytoplasm
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.79	EC:6.3.4.4	GO:0004019
0.79	KEGG:R01135	GO:0004019

tr|T1G8W7|T1G8W7_HELRO
Uncharacterized protein
Search

VRK1

0.90	serine/threonine-protein kinase VRK1

0.63	GO:0006468	protein phosphorylation
0.55	GO:0090166	Golgi disassembly
0.54	GO:0018209	peptidyl-serine modification
0.51	GO:0018210	peptidyl-threonine modification
0.48	GO:0016570	histone modification
0.46	GO:2000659	regulation of interleukin-1-mediated signaling pathway
0.43	GO:0008360	regulation of cell shape
0.42	GO:0043408	regulation of MAPK cascade
0.41	GO:0034599	cellular response to oxidative stress
0.35	GO:0007077	mitotic nuclear envelope disassembly

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0031493	nucleosomal histone binding
0.53	GO:0019901	protein kinase binding
0.42	GO:0019904	protein domain specific binding

0.50	GO:0005795	Golgi stack
0.47	GO:0005730	nucleolus
0.46	GO:0005654	nucleoplasm
0.45	GO:0005829	cytosol
0.41	GO:0005789	endoplasmic reticulum membrane
0.38	GO:0031966	mitochondrial membrane
0.38	GO:0043234	protein complex
0.37	GO:0005819	spindle
0.30	GO:0031224	intrinsic component of membrane

tr|T1G8W8|T1G8W8_HELRO
Uncharacterized protein
Search

0.48	Serine/threonine-protein kinase tricorner

0.63	GO:0006468	protein phosphorylation
0.46	GO:0048800	antennal morphogenesis
0.45	GO:0070593	dendrite self-avoidance
0.45	GO:0035317	imaginal disc-derived wing hair organization
0.44	GO:0022416	chaeta development
0.44	GO:0048814	regulation of dendrite morphogenesis
0.44	GO:0048813	dendrite morphogenesis
0.42	GO:0018209	peptidyl-serine modification
0.41	GO:0035556	intracellular signal transduction
0.37	GO:0043407	negative regulation of MAP kinase activity

0.70	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0031435	mitogen-activated protein kinase kinase kinase binding
0.37	GO:0045296	cadherin binding
0.36	GO:0000287	magnesium ion binding

0.46	GO:0070451	cell hair
0.43	GO:0030425	dendrite
0.43	GO:0044297	cell body
0.43	GO:0030424	axon
0.42	GO:0005938	cell cortex
0.39	GO:0005634	nucleus
0.36	GO:0005829	cytosol
0.35	GO:0015629	actin cytoskeleton
0.30	GO:0016020	membrane

0.70

GO:0004674

tr|T1G8W9|T1G8W9_HELRO
Uncharacterized protein
Search

0.65	Mitochondrial inner membrane protease subunit

0.72	GO:0006627	protein processing involved in protein targeting to mitochondrion
0.70	GO:0006465	signal peptide processing
0.50	GO:0033108	mitochondrial respiratory chain complex assembly
0.46	GO:0061300	cerebellum vasculature development
0.45	GO:0030728	ovulation
0.44	GO:0001541	ovarian follicle development
0.42	GO:0008015	blood circulation
0.42	GO:0007283	spermatogenesis
0.42	GO:0007420	brain development
0.41	GO:0006801	superoxide metabolic process

0.67	GO:0008236	serine-type peptidase activity
0.36	GO:0004175	endopeptidase activity
0.34	GO:0003743	translation initiation factor activity
0.33	GO:0003924	GTPase activity
0.33	GO:0004057	arginyltransferase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0022857	transmembrane transporter activity

0.75	GO:0042720	mitochondrial inner membrane peptidase complex
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:2.3.2.8

GO:0004057

tr|T1G8X0|T1G8X0_HELRO
Uncharacterized protein
Search

0.52	GO:0006357	regulation of transcription by RNA polymerase II
0.48	GO:0006396	RNA processing
0.41	GO:0009792	embryo development ending in birth or egg hatching
0.40	GO:0006974	cellular response to DNA damage stimulus

0.59	GO:0003723	RNA binding
0.44	GO:0003677	DNA binding
0.35	GO:0005515	protein binding

0.53	GO:0019013	viral nucleocapsid
0.47	GO:1990904	ribonucleoprotein complex
0.38	GO:0044424	intracellular part

tr|T1G8X1|T1G8X1_HELRO
Uncharacterized protein
Search

ERGIC2

0.89	Endoplasmic reticulum-Golgi intermediate compartment protein 2

0.54	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.35	GO:0043968	histone H2A acetylation
0.35	GO:0043967	histone H4 acetylation
0.34	GO:0006338	chromatin remodeling
0.34	GO:0006888	ER to Golgi vesicle-mediated transport
0.34	GO:0045892	negative regulation of transcription, DNA-templated
0.33	GO:0006281	DNA repair
0.33	GO:0032259	methylation

0.33	GO:0008168	methyltransferase activity
0.33	GO:0005515	protein binding

0.50	GO:0005730	nucleolus
0.39	GO:0005737	cytoplasm
0.36	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0098588	bounding membrane of organelle
0.36	GO:0031984	organelle subcompartment
0.35	GO:0035267	NuA4 histone acetyltransferase complex
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0008168

tr|T1G8X2|T1G8X2_HELRO
Uncharacterized protein
Search

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.51	GO:0000398	mRNA splicing, via spliceosome
0.50	GO:0071826	ribonucleoprotein complex subunit organization
0.46	GO:0051253	negative regulation of RNA metabolic process
0.46	GO:0010558	negative regulation of macromolecule biosynthetic process
0.46	GO:0031327	negative regulation of cellular biosynthetic process
0.45	GO:0034622	cellular macromolecular complex assembly
0.44	GO:0022613	ribonucleoprotein complex biogenesis

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.49	GO:0001067	regulatory region nucleic acid binding
0.35	GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity
0.35	GO:0005515	protein binding
0.33	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.33	GO:0005272	sodium channel activity

0.61	GO:0005634	nucleus
0.45	GO:0005829	cytosol
0.44	GO:0043233	organelle lumen
0.44	GO:0030529	intracellular ribonucleoprotein complex
0.43	GO:0044446	intracellular organelle part
0.41	GO:0043232	intracellular non-membrane-bounded organelle
0.34	GO:0045202	synapse
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0008138

tr|T1G8X3|T1G8X3_HELRO
Uncharacterized protein
Search

tr|T1G8X4|T1G8X4_HELRO
Uncharacterized protein
Search

SDHAF4

0.81	Succinate dehydrogenase complex assembly factor 4

0.81	GO:0097032	mitochondrial respiratory chain complex II biogenesis
0.81	GO:0034552	respiratory chain complex II assembly
0.78	GO:0003407	neural retina development
0.74	GO:0033108	mitochondrial respiratory chain complex assembly
0.66	GO:0045087	innate immune response
0.58	GO:0045333	cellular respiration
0.54	GO:0090175	regulation of establishment of planar polarity
0.51	GO:0034614	cellular response to reactive oxygen species
0.37	GO:0018108	peptidyl-tyrosine phosphorylation
0.37	GO:0006869	lipid transport

0.73	GO:0008177	succinate dehydrogenase (ubiquinone) activity
0.37	GO:0004713	protein tyrosine kinase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0003676	nucleic acid binding

0.58	GO:0005749	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)
0.40	GO:0005759	mitochondrial matrix
0.30	GO:0031224	intrinsic component of membrane

0.73	EC:1.3.5.1	GO:0008177
0.73	KEGG:R02164	GO:0008177

tr|T1G8X5|T1G8X5_HELRO
Uncharacterized protein
Search

DNAJB9

0.60	Dnaj protein dnaj homolog subfamily b member lik e dnaj homolog subfamily b member

0.66	GO:0009408	response to heat
0.64	GO:0006457	protein folding
0.56	GO:0006260	DNA replication
0.35	GO:0022900	electron transport chain

0.69	GO:0031072	heat shock protein binding
0.66	GO:0051082	unfolded protein binding
0.55	GO:0008270	zinc ion binding
0.50	GO:0030554	adenyl nucleotide binding
0.49	GO:0097367	carbohydrate derivative binding
0.49	GO:0008144	drug binding
0.49	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0020037	heme binding
0.35	GO:0009055	electron transfer activity
0.35	GO:0003676	nucleic acid binding

0.44	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1G8X6|T1G8X6_HELRO
Uncharacterized protein
Search

tr|T1G8X7|T1G8X7_HELRO
Uncharacterized protein
Search

MED23

0.76	Mediator of RNA polymerase II transcription subunit

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.46	GO:2000409	positive regulation of T cell extravasation
0.41	GO:0006351	transcription, DNA-templated
0.40	GO:0010604	positive regulation of macromolecule metabolic process
0.40	GO:0050768	negative regulation of neurogenesis
0.39	GO:0072358	cardiovascular system development
0.37	GO:0016567	protein ubiquitination

0.38	GO:0003713	transcription coactivator activity
0.38	GO:0061630	ubiquitin protein ligase activity
0.36	GO:0005515	protein binding

0.73	GO:0005667	transcription factor complex
0.42	GO:0005634	nucleus
0.41	GO:0031974	membrane-enclosed lumen
0.38	GO:0044446	intracellular organelle part
0.38	GO:0000151	ubiquitin ligase complex
0.30	GO:0016020	membrane

tr|T1G8X8|T1G8X8_HELRO
Uncharacterized protein
Search

P4HA2

0.76	Prolyl 4-hydroxylase subunit alpha-1

0.84	GO:0019511	peptidyl-proline hydroxylation
0.53	GO:0055114	oxidation-reduction process

0.84	GO:0004656	procollagen-proline 4-dioxygenase activity
0.79	GO:0031418	L-ascorbic acid binding
0.74	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.62	GO:0005506	iron ion binding

0.70	GO:0005783	endoplasmic reticulum
0.35	GO:0005654	nucleoplasm
0.35	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.84	EC:1.14.11.2	GO:0004656
0.84	KEGG:R03219	GO:0004656

tr|T1G8X9|T1G8X9_HELRO
Uncharacterized protein
Search

0.81	Prolyl 4-hydroxylase subunit alpha-1

0.83	GO:0019511	peptidyl-proline hydroxylation
0.53	GO:0055114	oxidation-reduction process
0.32	GO:0015031	protein transport

0.84	GO:0004656	procollagen-proline 4-dioxygenase activity
0.79	GO:0031418	L-ascorbic acid binding
0.73	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.63	GO:0005506	iron ion binding

0.69	GO:0005783	endoplasmic reticulum
0.30	GO:0031224	intrinsic component of membrane

0.84	EC:1.14.11.2	GO:0004656
0.84	KEGG:R03219	GO:0004656

tr|T1G8Y0|T1G8Y0_HELRO
Uncharacterized protein
Search

0.59	Speckle type BTB/POZ protein like

0.80	GO:1901044	protein polyubiquitination involved in nucleus-associated proteasomal ubiquitin-dependent protein catabolic process
0.75	GO:0007367	segment polarity determination
0.74	GO:0042067	establishment of ommatidial planar polarity
0.73	GO:0045879	negative regulation of smoothened signaling pathway
0.72	GO:0031648	protein destabilization
0.72	GO:0042308	negative regulation of protein import into nucleus
0.71	GO:0051865	protein autoubiquitination
0.71	GO:0046330	positive regulation of JNK cascade
0.68	GO:0030162	regulation of proteolysis
0.66	GO:0043065	positive regulation of apoptotic process

0.64	GO:0042803	protein homodimerization activity
0.53	GO:0031625	ubiquitin protein ligase binding
0.36	GO:0016887	ATPase activity
0.35	GO:0016491	oxidoreductase activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.57	GO:0005634	nucleus
0.57	GO:0031461	cullin-RING ubiquitin ligase complex
0.41	GO:0000808	origin recognition complex
0.39	GO:0005737	cytoplasm
0.38	GO:0043233	organelle lumen
0.30	GO:0031224	intrinsic component of membrane

0.36

GO:0016887

tr|T1G8Y1|T1G8Y1_HELRO
Uncharacterized protein
Search

SLC44A2

0.89	Solute carrier family 44 (choline transporter), member 2

0.37	GO:0061526	acetylcholine secretion
0.37	GO:0015871	choline transport
0.37	GO:0008292	acetylcholine biosynthetic process
0.36	GO:0030307	positive regulation of cell growth
0.35	GO:0032475	otolith formation
0.35	GO:0035675	neuromast hair cell development
0.35	GO:0030974	thiamine pyrophosphate transmembrane transport
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0006656	phosphatidylcholine biosynthetic process
0.34	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling

0.37	GO:0015220	choline transmembrane transporter activity
0.35	GO:0090422	thiamine pyrophosphate transmembrane transporter activity
0.33	GO:0004871	signal transducer activity

0.36	GO:0016324	apical plasma membrane
0.35	GO:0035579	specific granule membrane
0.34	GO:0005765	lysosomal membrane
0.34	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

tr|T1G8Y2|T1G8Y2_HELRO
Uncharacterized protein
Search

0.11	Putative splicing factor, arginine/serine-rich

0.45	GO:0001178	regulation of transcriptional start site selection at RNA polymerase II promoter
0.45	GO:0031440	regulation of mRNA 3'-end processing
0.44	GO:0006396	RNA processing
0.44	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.43	GO:0016071	mRNA metabolic process
0.37	GO:0022618	ribonucleoprotein complex assembly
0.34	GO:0090501	RNA phosphodiester bond hydrolysis
0.33	GO:0007219	Notch signaling pathway
0.33	GO:0016310	phosphorylation
0.33	GO:0051726	regulation of cell cycle

0.55	GO:0003723	RNA binding
0.34	GO:0016787	hydrolase activity
0.33	GO:0016301	kinase activity
0.33	GO:0003712	transcription cofactor activity
0.33	GO:0140098	catalytic activity, acting on RNA
0.33	GO:0046872	metal ion binding
0.33	GO:0003682	chromatin binding
0.33	GO:0008134	transcription factor binding
0.33	GO:0016758	transferase activity, transferring hexosyl groups
0.32	GO:0032559	adenyl ribonucleotide binding

0.41	GO:0005634	nucleus
0.38	GO:0120114	Sm-like protein family complex
0.36	GO:0030529	intracellular ribonucleoprotein complex
0.35	GO:0044446	intracellular organelle part
0.33	GO:1902494	catalytic complex
0.33	GO:0005615	extracellular space
0.32	GO:0005856	cytoskeleton
0.30	GO:0016020	membrane

0.34