Queries 21001 to 22000

GO:0004714

tr|T1G359|T1G359_HELRO
Uncharacterized protein
Search

0.56	GO:0072347	response to anesthetic
0.53	GO:0040017	positive regulation of locomotion
0.49	GO:0055080	cation homeostasis
0.45	GO:0034220	ion transmembrane transport
0.44	GO:0006812	cation transport
0.44	GO:0016567	protein ubiquitination

0.50	GO:0005261	cation channel activity
0.50	GO:0043130	ubiquitin binding
0.44	GO:0004842	ubiquitin-protein transferase activity
0.43	GO:0008270	zinc ion binding
0.42	GO:0016874	ligase activity
0.41	GO:0003723	RNA binding

0.53	GO:0030424	axon
0.51	GO:0034703	cation channel complex
0.36	GO:0005886	plasma membrane

0.42	EC:6	GO:0016874
0.44	KEGG:R03876	GO:0004842

tr|T1G360|T1G360_HELRO
Uncharacterized protein
Search

CI-ARM37

0.66	radial spoke head 14 homolog

tr|T1G361|T1G361_HELRO
Uncharacterized protein
Search

0.96	Mesotocin-neurophysin MT

0.76	GO:0010469	regulation of receptor activity
0.41	GO:0050801	ion homeostasis
0.36	GO:0070528	protein kinase C signaling
0.36	GO:0090201	negative regulation of release of cytochrome c from mitochondria
0.36	GO:0070371	ERK1 and ERK2 cascade
0.35	GO:0033138	positive regulation of peptidyl-serine phosphorylation
0.35	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.35	GO:0007218	neuropeptide signaling pathway
0.35	GO:0006915	apoptotic process
0.34	GO:0010628	positive regulation of gene expression

0.86	GO:0005185	neurohypophyseal hormone activity
0.36	GO:0031894	V1A vasopressin receptor binding
0.36	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.34	GO:0052795	exo-alpha-(2->6)-sialidase activity
0.34	GO:0052796	exo-alpha-(2->8)-sialidase activity
0.34	GO:0052794	exo-alpha-(2->3)-sialidase activity
0.33	GO:0004871	signal transducer activity
0.33	GO:0004672	protein kinase activity
0.33	GO:0090729	toxin activity

0.66	GO:0005576	extracellular region
0.32	GO:0005622	intracellular
0.30	GO:0016020	membrane

0.34

EC:3.2.1.18

GO:0052795

tr|T1G362|T1G362_HELRO
Uncharacterized protein
Search

0.47	Adenylyl cyclase class-3 4 guanylyl cyclase domain containing protein

0.76	GO:0009190	cyclic nucleotide biosynthetic process
0.71	GO:0046068	cGMP metabolic process
0.63	GO:0035556	intracellular signal transduction
0.59	GO:0009152	purine ribonucleotide biosynthetic process
0.52	GO:0006468	protein phosphorylation
0.49	GO:0045332	phospholipid translocation
0.38	GO:0050893	sensory processing
0.37	GO:0042048	olfactory behavior
0.37	GO:0007168	receptor guanylyl cyclase signaling pathway
0.36	GO:0007606	sensory perception of chemical stimulus

0.75	GO:0016849	phosphorus-oxygen lyase activity
0.68	GO:0009975	cyclase activity
0.53	GO:0004672	protein kinase activity
0.50	GO:1901265	nucleoside phosphate binding
0.49	GO:0004012	phospholipid-translocating ATPase activity
0.49	GO:0036094	small molecule binding
0.48	GO:0097367	carbohydrate derivative binding
0.48	GO:0008144	drug binding
0.47	GO:0043168	anion binding
0.43	GO:0000287	magnesium ion binding

0.45	GO:0005622	intracellular
0.37	GO:0043234	protein complex
0.37	GO:0044297	cell body
0.36	GO:0043005	neuron projection
0.36	GO:0005886	plasma membrane
0.34	GO:0036477	somatodendritic compartment
0.34	GO:0120038	plasma membrane bounded cell projection part
0.33	GO:0043235	receptor complex
0.30	GO:0016021	integral component of membrane

0.75

GO:0016849

tr|T1G363|T1G363_HELRO
Uncharacterized protein
Search

RAP1B

0.85	Rap GTPase

0.61	GO:0007165	signal transduction
0.46	GO:0061028	establishment of endothelial barrier
0.46	GO:0071320	cellular response to cAMP
0.45	GO:1901888	regulation of cell junction assembly
0.45	GO:2000301	negative regulation of synaptic vesicle exocytosis
0.43	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.41	GO:2000114	regulation of establishment of cell polarity
0.40	GO:0008283	cell proliferation
0.38	GO:2001214	positive regulation of vasculogenesis
0.38	GO:0040002	collagen and cuticulin-based cuticle development

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.44	GO:0019003	GDP binding
0.42	GO:0032403	protein complex binding
0.36	GO:0017016	Ras GTPase binding
0.36	GO:0008565	protein transporter activity
0.34	GO:0017056	structural constituent of nuclear pore
0.34	GO:0005085	guanyl-nucleotide exchange factor activity
0.33	GO:0016746	transferase activity, transferring acyl groups

0.42	GO:0030054	cell junction
0.42	GO:0005811	lipid droplet
0.40	GO:0005829	cytosol
0.38	GO:0032045	guanyl-nucleotide exchange factor complex
0.37	GO:0043209	myelin sheath
0.37	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0043005	neuron projection
0.35	GO:0005886	plasma membrane
0.34	GO:0045335	phagocytic vesicle
0.34	GO:0070062	extracellular exosome

0.33

EC:2.3

GO:0016746

tr|T1G364|T1G364_HELRO
Uncharacterized protein
Search

0.63	GO:0043484	regulation of RNA splicing
0.57	GO:0051726	regulation of cell cycle
0.56	GO:0016075	rRNA catabolic process
0.51	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.50	GO:0006397	mRNA processing
0.50	GO:0006364	rRNA processing
0.48	GO:0008033	tRNA processing
0.35	GO:0050684	regulation of mRNA processing
0.35	GO:0042981	regulation of apoptotic process
0.34	GO:0008380	RNA splicing

0.55	GO:0032296	double-stranded RNA-specific ribonuclease activity
0.55	GO:0003723	RNA binding
0.52	GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters
0.42	GO:0046872	metal ion binding

0.40	GO:0005737	cytoplasm
0.35	GO:0005681	spliceosomal complex

0.52

EC:3.1.26

GO:0016891

tr|T1G365|T1G365_HELRO
Uncharacterized protein
Search

0.51	Phenylalanine ammonia-lyase

0.84	GO:0009800	cinnamic acid biosynthetic process
0.80	GO:1902222	erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process
0.77	GO:0006558	L-phenylalanine metabolic process
0.76	GO:0009074	aromatic amino acid family catabolic process
0.70	GO:0042737	drug catabolic process

0.84	GO:0045548	phenylalanine ammonia-lyase activity
0.33	GO:0016407	acetyltransferase activity

0.49

GO:0005737

cytoplasm

0.84

EC:4.3.1.24 EC:4.3.1.25

GO:0045548

tr|T1G366|T1G366_HELRO
Uncharacterized protein
Search

0.50	Phenylalanine ammonia-lyase

0.84	GO:0009800	cinnamic acid biosynthetic process
0.80	GO:1902222	erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process
0.77	GO:0006558	L-phenylalanine metabolic process
0.75	GO:0009074	aromatic amino acid family catabolic process
0.70	GO:0042737	drug catabolic process

0.84	GO:0045548	phenylalanine ammonia-lyase activity
0.33	GO:0016407	acetyltransferase activity

0.48

GO:0005737

cytoplasm

0.84

EC:4.3.1.24 EC:4.3.1.25

GO:0045548

tr|T1G367|T1G367_HELRO
Cation-transporting ATPase
Search

0.63	Cation-transporting ATPase

0.60	GO:0006812	cation transport
0.43	GO:0072503	cellular divalent inorganic cation homeostasis
0.42	GO:0055074	calcium ion homeostasis
0.42	GO:0006875	cellular metal ion homeostasis
0.42	GO:0007626	locomotory behavior
0.41	GO:0043009	chordate embryonic development
0.40	GO:0099131	ATP hydrolysis coupled ion transmembrane transport
0.38	GO:0098660	inorganic ion transmembrane transport
0.35	GO:0055069	zinc ion homeostasis
0.35	GO:0055071	manganese ion homeostasis

0.60	GO:0016887	ATPase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0046872	metal ion binding
0.42	GO:0015085	calcium ion transmembrane transporter activity
0.40	GO:0022853	active ion transmembrane transporter activity
0.39	GO:0015399	primary active transmembrane transporter activity
0.32	GO:0003676	nucleic acid binding

0.39	GO:0005887	integral component of plasma membrane
0.37	GO:0043231	intracellular membrane-bounded organelle
0.36	GO:0098805	whole membrane
0.36	GO:0098588	bounding membrane of organelle
0.35	GO:1990816	vacuole-mitochondrion membrane contact site
0.35	GO:0031410	cytoplasmic vesicle
0.34	GO:0044446	intracellular organelle part
0.34	GO:0016324	apical plasma membrane

0.60

GO:0016887

tr|T1G368|T1G368_HELRO
Uncharacterized protein
Search

TMTC2

0.95	Transmembrane and tetratricopeptide repeat containing 2

0.51	GO:0055074	calcium ion homeostasis
0.46	GO:0006493	protein O-linked glycosylation
0.45	GO:0097502	mannosylation
0.32	GO:0016310	phosphorylation

0.45	GO:0000030	mannosyltransferase activity
0.38	GO:0042802	identical protein binding
0.32	GO:0016772	transferase activity, transferring phosphorus-containing groups

0.47	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.45

GO:0000030

tr|T1G369|T1G369_HELRO
Uncharacterized protein
Search

RRAGA

0.85	Ras-related GTP-binding protein A

0.53	GO:0071230	cellular response to amino acid stimulus
0.51	GO:0032008	positive regulation of TOR signaling
0.50	GO:0034198	cellular response to amino acid starvation
0.49	GO:1903432	regulation of TORC1 signaling
0.49	GO:0045919	positive regulation of cytolysis
0.48	GO:0010506	regulation of autophagy
0.45	GO:0008219	cell death
0.44	GO:0031330	negative regulation of cellular catabolic process
0.44	GO:0034613	cellular protein localization
0.42	GO:0019048	modulation by virus of host morphology or physiology

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0032561	guanyl ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0051219	phosphoprotein binding
0.46	GO:0046982	protein heterodimerization activity
0.46	GO:0003924	GTPase activity
0.45	GO:0031625	ubiquitin protein ligase binding
0.44	GO:0042803	protein homodimerization activity
0.38	GO:0051020	GTPase binding

0.50	GO:0005764	lysosome
0.49	GO:1990130	GATOR1 complex
0.49	GO:1990131	Gtr1-Gtr2 GTPase complex
0.48	GO:0034448	EGO complex
0.43	GO:0005634	nucleus
0.36	GO:0098852	lytic vacuole membrane
0.34	GO:0005829	cytosol

tr|T1G370|T1G370_HELRO
Uncharacterized protein
Search

COPS7B

0.87	COP9 signalosome complex subunit 7

0.47	GO:0000338	protein deneddylation
0.34	GO:0043687	post-translational protein modification
0.34	GO:0000715	nucleotide-excision repair, DNA damage recognition
0.34	GO:0006283	transcription-coupled nucleotide-excision repair

0.33

GO:0005515

protein binding

0.79	GO:0008180	COP9 signalosome
0.38	GO:0005654	nucleoplasm
0.36	GO:0005829	cytosol
0.33	GO:1905369	endopeptidase complex

tr|T1G371|T1G371_HELRO
Uncharacterized protein
Search

tr|T1G372|T1G372_HELRO
Anaphase-promoting complex subunit 10
Search

ANAPC10

0.77	Anaphase-promoting complex subunit 10

0.83	GO:0031145	anaphase-promoting complex-dependent catabolic process
0.65	GO:0051301	cell division
0.65	GO:0007049	cell cycle
0.55	GO:0070979	protein K11-linked ubiquitination
0.47	GO:1904668	positive regulation of ubiquitin protein ligase activity
0.43	GO:2000736	regulation of stem cell differentiation
0.34	GO:1904667	negative regulation of ubiquitin protein ligase activity
0.34	GO:2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.34	GO:0060964	regulation of gene silencing by miRNA
0.34	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process

0.45	GO:0061630	ubiquitin protein ligase activity
0.33	GO:0030246	carbohydrate binding
0.33	GO:0016853	isomerase activity
0.33	GO:0005515	protein binding

0.80	GO:0005680	anaphase-promoting complex
0.37	GO:0005737	cytoplasm
0.33	GO:0005654	nucleoplasm

0.33

EC:5

GO:0016853

tr|T1G373|T1G373_HELRO
Uncharacterized protein
Search

RECQ5

0.36	ATP-dependent DNA helicase

0.65	GO:0006310	DNA recombination
0.50	GO:0006302	double-strand break repair
0.48	GO:0000278	mitotic cell cycle
0.48	GO:0045910	negative regulation of DNA recombination
0.48	GO:0032392	DNA geometric change
0.48	GO:0072757	cellular response to camptothecin
0.47	GO:0007059	chromosome segregation
0.47	GO:0010165	response to X-ray
0.47	GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter
0.46	GO:2000780	negative regulation of double-strand break repair

0.71	GO:0070035	purine NTP-dependent helicase activity
0.64	GO:0042623	ATPase activity, coupled
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0003676	nucleic acid binding
0.48	GO:0003678	DNA helicase activity
0.46	GO:0000993	RNA polymerase II core binding
0.41	GO:0003924	GTPase activity
0.41	GO:0032550	purine ribonucleoside binding

0.52	GO:0005634	nucleus
0.43	GO:0000428	DNA-directed RNA polymerase complex
0.41	GO:0005829	cytosol
0.41	GO:0031974	membrane-enclosed lumen
0.40	GO:0005694	chromosome
0.38	GO:0044446	intracellular organelle part
0.32	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.34

GO:0018024

tr|T1G374|T1G374_HELRO
Uncharacterized protein
Search

0.54	GO:0006898	receptor-mediated endocytosis
0.52	GO:1905167	positive regulation of lysosomal protein catabolic process
0.51	GO:0097242	amyloid-beta clearance
0.51	GO:0002265	astrocyte activation involved in immune response
0.50	GO:1900223	positive regulation of amyloid-beta clearance
0.50	GO:0045056	transcytosis
0.49	GO:1904646	cellular response to amyloid-beta
0.49	GO:1903078	positive regulation of protein localization to plasma membrane
0.49	GO:0032092	positive regulation of protein binding
0.48	GO:0045807	positive regulation of endocytosis

0.63	GO:0005509	calcium ion binding
0.59	GO:0038024	cargo receptor activity
0.51	GO:0032050	clathrin heavy chain binding
0.50	GO:0034185	apolipoprotein binding
0.48	GO:0004252	serine-type endopeptidase activity
0.45	GO:0032403	protein complex binding
0.37	GO:0002020	protease binding
0.35	GO:0030226	apolipoprotein receptor activity
0.35	GO:0043395	heparan sulfate proteoglycan binding
0.34	GO:0070325	lipoprotein particle receptor binding

0.48	GO:0043235	receptor complex
0.48	GO:0016323	basolateral plasma membrane
0.47	GO:0005769	early endosome
0.39	GO:0005615	extracellular space
0.37	GO:0005579	membrane attack complex
0.37	GO:0005765	lysosomal membrane
0.37	GO:0043025	neuronal cell body
0.37	GO:0030425	dendrite
0.36	GO:0030136	clathrin-coated vesicle
0.36	GO:0005794	Golgi apparatus

0.48

GO:0004252

tr|T1G375|T1G375_HELRO
Uncharacterized protein
Search

0.10	Paired box protein Pax-7 (Fragment)

0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:0010468	regulation of gene expression
0.35	GO:0048665	neuron fate specification
0.34	GO:1902680	positive regulation of RNA biosynthetic process

0.61

GO:0043565

sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.30	GO:0044425	membrane part

tr|T1G376|T1G376_HELRO
Uncharacterized protein
Search

0.56	GO:0007275	multicellular organism development
0.48	GO:2001141	regulation of RNA biosynthetic process
0.48	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.48	GO:0010468	regulation of gene expression
0.44	GO:0001708	cell fate specification
0.43	GO:0061061	muscle structure development
0.42	GO:0061448	connective tissue development
0.42	GO:0014706	striated muscle tissue development
0.42	GO:2000741	positive regulation of mesenchymal stem cell differentiation
0.41	GO:2000726	negative regulation of cardiac muscle cell differentiation

0.55	GO:0003677	DNA binding
0.40	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.39	GO:0001067	regulatory region nucleic acid binding
0.38	GO:0046982	protein heterodimerization activity
0.33	GO:0017025	TBP-class protein binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005634	nucleus
0.37	GO:0070013	intracellular organelle lumen
0.35	GO:0044446	intracellular organelle part
0.33	GO:0005700	polytene chromosome
0.30	GO:0016020	membrane

tr|T1G377|T1G377_HELRO
Uncharacterized protein
Search

DOK5

0.69	Docking protein 5

0.75	GO:0000165	MAPK cascade
0.74	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.72	GO:0007399	nervous system development
0.55	GO:0051386	regulation of neurotrophin TRK receptor signaling pathway
0.43	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.43	GO:0000904	cell morphogenesis involved in differentiation
0.43	GO:0120036	plasma membrane bounded cell projection organization
0.41	GO:0006935	chemotaxis
0.41	GO:0006928	movement of cell or subcellular component

0.75	GO:0005057	signal transducer activity, downstream of receptor
0.39	GO:0005515	protein binding
0.36	GO:0016301	kinase activity

0.44

GO:0005622

intracellular

tr|T1G378|T1G378_HELRO
Uncharacterized protein
Search

GTF2F2

0.92	General transcription factor IIF subunit 2

0.78	GO:0006367	transcription initiation from RNA polymerase II promoter
0.53	GO:2001141	regulation of RNA biosynthetic process
0.53	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.53	GO:0010468	regulation of gene expression
0.47	GO:0031334	positive regulation of protein complex assembly
0.45	GO:0051254	positive regulation of RNA metabolic process
0.45	GO:0010557	positive regulation of macromolecule biosynthetic process
0.44	GO:0031328	positive regulation of cellular biosynthetic process
0.35	GO:0006413	translational initiation
0.35	GO:0042795	snRNA transcription by RNA polymerase II

0.62	GO:0004386	helicase activity
0.51	GO:0032559	adenyl ribonucleotide binding
0.51	GO:0003677	DNA binding
0.50	GO:0008144	drug binding
0.50	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0000991	transcription factor activity, core RNA polymerase II binding
0.35	GO:0003743	translation initiation factor activity
0.33	GO:0005515	protein binding

0.84	GO:0005674	transcription factor TFIIF complex
0.54	GO:0097550	transcriptional preinitiation complex
0.47	GO:0015630	microtubule cytoskeleton
0.35	GO:0005675	holo TFIIH complex

tr|T1G379|T1G379_HELRO
Uncharacterized protein
Search

0.38	GO:0016042	lipid catabolic process
0.36	GO:0035556	intracellular signal transduction

0.40	GO:0004435	phosphatidylinositol phospholipase C activity
0.36	GO:0004871	signal transducer activity
0.36	GO:0005515	protein binding

0.69	GO:0005654	nucleoplasm
0.67	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.40	EC:3.1.4.11	GO:0004435
0.40	KEGG:R03435	GO:0004435

tr|T1G380|T1G380_HELRO
Uncharacterized protein
Search

0.58	GO:0032259	methylation
0.38	GO:0006400	tRNA modification
0.35	GO:0018108	peptidyl-tyrosine phosphorylation
0.33	GO:0006281	DNA repair

0.59	GO:0008168	methyltransferase activity
0.38	GO:0140101	catalytic activity, acting on a tRNA
0.35	GO:0004713	protein tyrosine kinase activity
0.33	GO:0003723	RNA binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0008270	zinc ion binding

0.30

GO:0016020

membrane

0.59

GO:0008168

tr|T1G381|T1G381_HELRO
Uncharacterized protein
Search

0.50	Ubiquitin-conjugating enzyme

0.40	GO:0019915	lipid storage
0.38	GO:0016567	protein ubiquitination
0.35	GO:0016571	histone methylation
0.34	GO:0045892	negative regulation of transcription, DNA-templated
0.34	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.34	GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0004842	ubiquitin-protein transferase activity
0.37	GO:0016874	ligase activity
0.34	GO:0043021	ribonucleoprotein complex binding
0.33	GO:0004386	helicase activity

0.36	GO:0035098	ESC/E(Z) complex
0.34	GO:0030687	preribosome, large subunit precursor
0.34	GO:0005730	nucleolus
0.30	GO:0016020	membrane

0.37	EC:6	GO:0016874
0.38	KEGG:R03876	GO:0004842

tr|T1G382|T1G382_HELRO
Uncharacterized protein
Search

PIGC

0.94	Phosphatidylinositol N-acetylglucosaminyltransferase subunit C

0.78	GO:0006506	GPI anchor biosynthetic process
0.39	GO:0045313	rhabdomere membrane biogenesis
0.33	GO:0006471	protein ADP-ribosylation
0.32	GO:0007165	signal transduction

0.84	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity
0.33	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.32	GO:0008270	zinc ion binding
0.32	GO:0003723	RNA binding

0.56	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex
0.32	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.84

EC:2.4.1.198

GO:0017176

tr|T1G383|T1G383_HELRO
Uncharacterized protein
Search

0.65	GO:0006278	RNA-dependent DNA biosynthetic process
0.36	GO:0007165	signal transduction
0.36	GO:0006030	chitin metabolic process
0.36	GO:0035023	regulation of Rho protein signal transduction
0.36	GO:0006108	malate metabolic process
0.34	GO:0065009	regulation of molecular function
0.34	GO:0019538	protein metabolic process
0.34	GO:0005975	carbohydrate metabolic process
0.33	GO:0043412	macromolecule modification
0.33	GO:0016310	phosphorylation

0.65	GO:0003964	RNA-directed DNA polymerase activity
0.36	GO:0005201	extracellular matrix structural constituent
0.36	GO:0008061	chitin binding
0.36	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.36	GO:0030060	L-malate dehydrogenase activity
0.35	GO:0008270	zinc ion binding
0.35	GO:0004180	carboxypeptidase activity
0.35	GO:0004930	G-protein coupled receptor activity
0.35	GO:0005509	calcium ion binding
0.35	GO:0046983	protein dimerization activity

0.35	GO:0005576	extracellular region
0.34	GO:0005634	nucleus
0.34	GO:0005856	cytoskeleton
0.30	GO:0016020	membrane

0.65

GO:0003964

tr|T1G384|T1G384_HELRO
Uncharacterized protein
Search

0.41	ATP-dependent RNA helicase abstrakt

0.41	GO:0010501	RNA secondary structure unwinding
0.35	GO:0000398	mRNA splicing, via spliceosome
0.35	GO:0035458	cellular response to interferon-beta
0.34	GO:0008283	cell proliferation
0.34	GO:0051607	defense response to virus
0.34	GO:0006334	nucleosome assembly
0.34	GO:0045944	positive regulation of transcription by RNA polymerase II
0.34	GO:0030154	cell differentiation

0.59	GO:0004386	helicase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0003676	nucleic acid binding
0.50	GO:0008270	zinc ion binding
0.40	GO:0008186	RNA-dependent ATPase activity
0.37	GO:0140098	catalytic activity, acting on RNA

0.42	GO:0071013	catalytic step 2 spliceosome
0.39	GO:0005730	nucleolus
0.34	GO:0071011	precatalytic spliceosome
0.34	GO:0005737	cytoplasm
0.33	GO:0012505	endomembrane system
0.30	GO:0031224	intrinsic component of membrane

tr|T1G385|T1G385_HELRO
Uncharacterized protein
Search

0.61	GO:0006508	proteolysis
0.46	GO:0007340	acrosome reaction
0.44	GO:0007190	activation of adenylate cyclase activity
0.43	GO:0007341	penetration of zona pellucida
0.42	GO:0007339	binding of sperm to zona pellucida
0.41	GO:0006898	receptor-mediated endocytosis
0.40	GO:0007596	blood coagulation
0.36	GO:0007313	maternal specification of dorsal/ventral axis, oocyte, soma encoded
0.36	GO:0007306	eggshell chorion assembly
0.35	GO:0002803	positive regulation of antibacterial peptide production

0.69	GO:0004252	serine-type endopeptidase activity
0.44	GO:0005537	mannose binding
0.43	GO:0005044	scavenger receptor activity
0.37	GO:0042806	fucose binding
0.36	GO:0004040	amidase activity
0.34	GO:0005507	copper ion binding
0.34	GO:0005509	calcium ion binding
0.34	GO:0002020	protease binding
0.34	GO:0008270	zinc ion binding
0.33	GO:0008144	drug binding

0.57	GO:0001669	acrosomal vesicle
0.39	GO:0044437	vacuolar part
0.39	GO:0044433	cytoplasmic vesicle part
0.38	GO:0005576	extracellular region
0.37	GO:0043234	protein complex
0.35	GO:0097209	epidermal lamellar body
0.34	GO:0005798	Golgi-associated vesicle
0.33	GO:0046658	anchored component of plasma membrane
0.33	GO:0019897	extrinsic component of plasma membrane
0.33	GO:0005634	nucleus

0.69

GO:0004252

tr|T1G386|T1G386_HELRO
Uncharacterized protein
Search

0.50	Reverse transcriptase-like protein

0.70

GO:0006278

RNA-dependent DNA biosynthetic process

0.70

GO:0003964

RNA-directed DNA polymerase activity

0.30

GO:0031224

intrinsic component of membrane

0.70

GO:0003964

tr|T1G387|T1G387_HELRO
Uncharacterized protein
Search

0.66	GO:0006887	exocytosis
0.54	GO:0099643	signal release from synapse
0.54	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.51	GO:0006836	neurotransmitter transport
0.49	GO:0001505	regulation of neurotransmitter levels
0.49	GO:0090119	vesicle-mediated cholesterol transport
0.49	GO:0017158	regulation of calcium ion-dependent exocytosis
0.49	GO:1990926	short-term synaptic potentiation
0.48	GO:0070092	regulation of glucagon secretion
0.48	GO:0048489	synaptic vesicle transport

0.72	GO:0005544	calcium-dependent phospholipid binding
0.47	GO:0000149	SNARE binding
0.47	GO:0001786	phosphatidylserine binding
0.46	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.44	GO:0005516	calmodulin binding
0.42	GO:0030276	clathrin binding
0.40	GO:0046872	metal ion binding

0.57	GO:0045202	synapse
0.52	GO:0097458	neuron part
0.51	GO:0070382	exocytic vesicle
0.47	GO:0032009	early phagosome
0.45	GO:0044297	cell body
0.44	GO:0005764	lysosome
0.43	GO:0098590	plasma membrane region
0.43	GO:0005777	peroxisome
0.43	GO:0120038	plasma membrane bounded cell projection part
0.41	GO:0005829	cytosol

tr|T1G388|T1G388_HELRO
Kinesin-like protein
Search

0.74	GO:0007018	microtubule-based movement
0.39	GO:0044782	cilium organization
0.39	GO:0010938	cytoplasmic microtubule depolymerization
0.39	GO:0070462	plus-end specific microtubule depolymerization
0.37	GO:1903008	organelle disassembly
0.37	GO:0022607	cellular component assembly
0.37	GO:0002183	cytoplasmic translational initiation
0.36	GO:0006446	regulation of translational initiation
0.36	GO:0071826	ribonucleoprotein complex subunit organization
0.36	GO:0007186	G-protein coupled receptor signaling pathway

0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0016887	ATPase activity
0.37	GO:0031369	translation initiation factor binding
0.36	GO:0005230	extracellular ligand-gated ion channel activity
0.36	GO:0004930	G-protein coupled receptor activity
0.36	GO:0003743	translation initiation factor activity

0.68	GO:0005874	microtubule
0.48	GO:0005871	kinesin complex
0.39	GO:0005929	cilium
0.37	GO:0032838	plasma membrane bounded cell projection cytoplasm
0.37	GO:0016282	eukaryotic 43S preinitiation complex
0.37	GO:0033290	eukaryotic 48S preinitiation complex
0.36	GO:0005852	eukaryotic translation initiation factor 3 complex
0.30	GO:0016020	membrane

0.41

GO:0016887

tr|T1G390|T1G390_HELRO
Uncharacterized protein
Search

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.64	GO:0071310	cellular response to organic substance
0.61	GO:0009725	response to hormone
0.61	GO:0071495	cellular response to endogenous stimulus
0.56	GO:0001570	vasculogenesis
0.54	GO:0001525	angiogenesis
0.53	GO:0034097	response to cytokine
0.50	GO:0006935	chemotaxis
0.50	GO:0007166	cell surface receptor signaling pathway
0.49	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage

0.72	GO:0008528	G-protein coupled peptide receptor activity
0.57	GO:0019956	chemokine binding
0.56	GO:0015026	coreceptor activity
0.48	GO:0004896	cytokine receptor activity
0.46	GO:0005044	scavenger receptor activity
0.46	GO:0042923	neuropeptide binding
0.38	GO:0050254	rhodopsin kinase activity
0.35	GO:0008227	G-protein coupled amine receptor activity
0.35	GO:0017046	peptide hormone binding
0.35	GO:0099528	G-protein coupled neurotransmitter receptor activity

0.46	GO:0005905	clathrin-coated pit
0.44	GO:0009986	cell surface
0.44	GO:0005768	endosome
0.44	GO:0005886	plasma membrane
0.43	GO:0043005	neuron projection
0.38	GO:0043231	intracellular membrane-bounded organelle
0.36	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0043235	receptor complex
0.30	GO:0016021	integral component of membrane

0.38

EC:2.7.11.14

GO:0050254

tr|T1G391|T1G391_HELRO
Guanylate cyclase
Search

0.50	Guanylate cyclase

0.81	GO:0006182	cGMP biosynthetic process
0.62	GO:0006468	protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.35	GO:0007428	primary branching, open tracheal system
0.35	GO:0042330	taxis
0.35	GO:0018212	peptidyl-tyrosine modification
0.35	GO:0061067	negative regulation of dauer larval development
0.35	GO:0007526	larval somatic muscle development
0.35	GO:0090325	regulation of locomotion involved in locomotory behavior
0.35	GO:0120036	plasma membrane bounded cell projection organization

0.82	GO:0004383	guanylate cyclase activity
0.63	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0004016	adenylate cyclase activity
0.36	GO:0032550	purine ribonucleoside binding
0.36	GO:0019001	guanyl nucleotide binding
0.35	GO:0030215	semaphorin receptor binding
0.34	GO:0004872	receptor activity

0.45	GO:0008074	guanylate cyclase complex, soluble
0.40	GO:0009897	external side of plasma membrane
0.35	GO:0043005	neuron projection
0.35	GO:0005929	cilium
0.35	GO:0120038	plasma membrane bounded cell projection part
0.34	GO:0043204	perikaryon
0.34	GO:0005887	integral component of plasma membrane
0.34	GO:0005902	microvillus
0.33	GO:0098590	plasma membrane region

0.82

GO:0004383

tr|T1G392|T1G392_HELRO
Uncharacterized protein
Search

0.37	Serine threonine kinase

0.63	GO:0006468	protein phosphorylation
0.60	GO:0042981	regulation of apoptotic process
0.51	GO:0060997	dendritic spine morphogenesis
0.51	GO:0032147	activation of protein kinase activity
0.50	GO:0043408	regulation of MAPK cascade
0.49	GO:0007409	axonogenesis
0.48	GO:0071902	positive regulation of protein serine/threonine kinase activity
0.47	GO:0030833	regulation of actin filament polymerization
0.47	GO:1902533	positive regulation of intracellular signal transduction
0.47	GO:0031098	stress-activated protein kinase signaling cascade

0.68	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0004708	MAP kinase kinase activity
0.50	GO:0017048	Rho GTPase binding
0.38	GO:0017124	SH3 domain binding
0.35	GO:0019001	guanyl nucleotide binding
0.35	GO:0046872	metal ion binding

0.39	GO:0030056	hemidesmosome
0.38	GO:0005829	cytosol
0.37	GO:0043025	neuronal cell body
0.37	GO:0030424	axon
0.37	GO:0005882	intermediate filament
0.36	GO:0005768	endosome
0.36	GO:0005886	plasma membrane
0.35	GO:0031252	cell leading edge
0.35	GO:0005634	nucleus
0.34	GO:0005938	cell cortex

0.68

GO:0004674

tr|T1G393|T1G393_HELRO
Uncharacterized protein
Search

0.65	GO:0007155	cell adhesion
0.51	GO:0021961	posterior commissure morphogenesis
0.48	GO:0006468	protein phosphorylation
0.44	GO:0035023	regulation of Rho protein signal transduction
0.40	GO:0065009	regulation of molecular function
0.38	GO:0071688	striated muscle myosin thick filament assembly
0.37	GO:0045214	sarcomere organization
0.37	GO:0006941	striated muscle contraction
0.36	GO:0007015	actin filament organization

0.48	GO:0004672	protein kinase activity
0.44	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.43	GO:0032559	adenyl ribonucleotide binding
0.43	GO:0008144	drug binding
0.43	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0097493	structural molecule activity conferring elasticity
0.38	GO:0051371	muscle alpha-actinin binding
0.37	GO:0008307	structural constituent of muscle
0.36	GO:0051015	actin filament binding

0.38	GO:0005859	muscle myosin complex
0.37	GO:0031430	M band
0.37	GO:0030018	Z disc
0.30	GO:0031224	intrinsic component of membrane

tr|T1G394|T1G394_HELRO
Uncharacterized protein
Search

0.97	Regulation of wnt receptor signaling pathway

0.81	GO:2000009	negative regulation of protein localization to cell surface
0.76	GO:0007266	Rho protein signal transduction
0.76	GO:0090630	activation of GTPase activity
0.75	GO:0030178	negative regulation of Wnt signaling pathway
0.72	GO:0008285	negative regulation of cell proliferation
0.57	GO:0060028	convergent extension involved in axis elongation
0.42	GO:0016055	Wnt signaling pathway
0.40	GO:0006468	protein phosphorylation

0.75	GO:0008013	beta-catenin binding
0.75	GO:0008022	protein C-terminus binding
0.40	GO:0004672	protein kinase activity
0.38	GO:0016757	transferase activity, transferring glycosyl groups
0.38	GO:0032559	adenyl ribonucleotide binding
0.38	GO:0000287	magnesium ion binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding

0.75	GO:0001650	fibrillar center
0.67	GO:0015629	actin cytoskeleton
0.46	GO:0005737	cytoplasm
0.39	GO:0070062	extracellular exosome
0.37	GO:0005886	plasma membrane

0.38

GO:0016757

tr|T1G395|T1G395_HELRO
Uncharacterized protein
Search

0.60	GO:0005975	carbohydrate metabolic process
0.37	GO:0044248	cellular catabolic process
0.36	GO:1901575	organic substance catabolic process
0.33	GO:0009058	biosynthetic process

0.50	GO:0016798	hydrolase activity, acting on glycosyl bonds
0.37	GO:0043169	cation binding

0.35	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.50

EC:3.2

GO:0016798

tr|T1G396|T1G396_HELRO
Uncharacterized protein
Search

0.47	GO:0031960	response to corticosteroid
0.46	GO:0007283	spermatogenesis
0.40	GO:0007275	multicellular organism development
0.40	GO:0006357	regulation of transcription by RNA polymerase II
0.39	GO:0001708	cell fate specification
0.38	GO:0008283	cell proliferation
0.38	GO:0036445	neuronal stem cell division
0.38	GO:0098722	asymmetric stem cell division
0.38	GO:0009653	anatomical structure morphogenesis
0.38	GO:0045026	plasma membrane fusion

0.55	GO:0003677	DNA binding
0.40	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.35	GO:0003682	chromatin binding
0.35	GO:0001067	regulatory region nucleic acid binding
0.34	GO:0004084	branched-chain-amino-acid transaminase activity
0.34	GO:0097157	pre-mRNA intronic binding
0.34	GO:0034236	protein kinase A catalytic subunit binding
0.34	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.34	GO:0008013	beta-catenin binding
0.33	GO:0004672	protein kinase activity

0.61	GO:0005634	nucleus
0.34	GO:0031315	extrinsic component of mitochondrial outer membrane
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0005667	transcription factor complex
0.30	GO:0016021	integral component of membrane

0.34

EC:2.6.1.42

GO:0004084

tr|T1G397|T1G397_HELRO
Uncharacterized protein
Search

0.72	GO:0051289	protein homotetramerization
0.72	GO:0008154	actin polymerization or depolymerization
0.71	GO:0044089	positive regulation of cellular component biogenesis
0.70	GO:0032956	regulation of actin cytoskeleton organization
0.68	GO:1902905	positive regulation of supramolecular fiber organization
0.67	GO:0051495	positive regulation of cytoskeleton organization
0.67	GO:0032271	regulation of protein polymerization
0.67	GO:0032535	regulation of cellular component size
0.56	GO:0007396	suture of dorsal opening
0.55	GO:0120032	regulation of plasma membrane bounded cell projection assembly

0.72	GO:0017124	SH3 domain binding
0.64	GO:0003779	actin binding
0.48	GO:0005522	profilin binding
0.35	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
0.34	GO:0043565	sequence-specific DNA binding
0.34	GO:0003700	DNA binding transcription factor activity

0.60	GO:0005856	cytoskeleton
0.55	GO:0030027	lamellipodium
0.54	GO:0005912	adherens junction
0.54	GO:0071212	subsynaptic reticulum
0.52	GO:0032433	filopodium tip
0.49	GO:0030425	dendrite
0.48	GO:0005911	cell-cell junction
0.45	GO:0030055	cell-substrate junction
0.45	GO:0005829	cytosol
0.45	GO:0045335	phagocytic vesicle

0.35

EC:1.3.1

GO:0016628

tr|T1G398|T1G398_HELRO
Uncharacterized protein
Search

0.65	Potassium voltage-gated channel subfamily H member 4

0.73	GO:0034765	regulation of ion transmembrane transport
0.71	GO:0071805	potassium ion transmembrane transport
0.62	GO:0023014	signal transduction by protein phosphorylation
0.59	GO:0000160	phosphorelay signal transduction system
0.47	GO:0042391	regulation of membrane potential
0.34	GO:0007631	feeding behavior
0.34	GO:0007218	neuropeptide signaling pathway
0.34	GO:0043066	negative regulation of apoptotic process
0.34	GO:0006357	regulation of transcription by RNA polymerase II

0.76	GO:0005249	voltage-gated potassium channel activity
0.63	GO:0000155	phosphorelay sensor kinase activity
0.35	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.35	GO:0003924	GTPase activity
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0019001	guanyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.43	GO:0005887	integral component of plasma membrane
0.43	GO:0005622	intracellular
0.34	GO:0034705	potassium channel complex

0.63

EC:2.7.3

GO:0000155

tr|T1G399|T1G399_HELRO
Uncharacterized protein
Search

0.74	GO:0051568	histone H3-K4 methylation
0.37	GO:0006420	arginyl-tRNA aminoacylation

0.71	GO:0018024	histone-lysine N-methyltransferase activity
0.58	GO:0003723	RNA binding
0.37	GO:0004814	arginine-tRNA ligase activity
0.34	GO:0008270	zinc ion binding
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.71	GO:0048188	Set1C/COMPASS complex
0.33	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.71

GO:0018024

tr|T1G3A0|T1G3A0_HELRO
Uncharacterized protein
Search

ZCRB1

0.62	Zinc finger CCHC-type and RNA-binding motif-containing protein 1

0.50	GO:0000398	mRNA splicing, via spliceosome
0.45	GO:0051302	regulation of cell division
0.42	GO:0032502	developmental process

0.62	GO:0008270	zinc ion binding
0.59	GO:0003723	RNA binding

0.52	GO:0005689	U12-type spliceosomal complex
0.42	GO:0019013	viral nucleocapsid
0.35	GO:0005654	nucleoplasm

tr|T1G3A1|T1G3A1_HELRO
Uncharacterized protein
Search

0.61	Spermatogenesis-associated protein 5 (Fragment)

0.45	GO:0007420	brain development
0.42	GO:0051013	microtubule severing
0.42	GO:0042273	ribosomal large subunit biogenesis
0.40	GO:0042493	response to drug
0.35	GO:0007283	spermatogenesis
0.34	GO:0030154	cell differentiation
0.33	GO:0046160	heme a metabolic process
0.33	GO:0051301	cell division
0.33	GO:0006783	heme biosynthetic process
0.33	GO:0030001	metal ion transport

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0008568	microtubule-severing ATPase activity
0.33	GO:0019904	protein domain specific binding
0.33	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors
0.32	GO:0004672	protein kinase activity
0.32	GO:0003924	GTPase activity
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0032561	guanyl ribonucleotide binding

0.43	GO:0030687	preribosome, large subunit precursor
0.36	GO:0005737	cytoplasm
0.33	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016020	membrane

0.42

EC:3.6.4.3

GO:0008568

tr|T1G3A2|T1G3A2_HELRO
Uncharacterized protein
Search

0.64	RANBP2-like and GRIP domain-containing protein 8

0.78	GO:0071955	recycling endosome to Golgi transport
0.77	GO:0034499	late endosome to Golgi transport
0.76	GO:0090161	Golgi ribbon formation
0.75	GO:0006622	protein targeting to lysosome
0.74	GO:0070861	regulation of protein exit from endoplasmic reticulum
0.71	GO:0034067	protein localization to Golgi apparatus
0.71	GO:0034453	microtubule anchoring
0.69	GO:0031023	microtubule organizing center organization
0.41	GO:0043001	Golgi to plasma membrane protein transport
0.38	GO:0046604	positive regulation of mitotic centrosome separation

0.63	GO:0042802	identical protein binding
0.39	GO:0008536	Ran GTPase binding
0.38	GO:0070840	dynein complex binding
0.36	GO:0008134	transcription factor binding
0.36	GO:0005096	GTPase activator activity
0.35	GO:0046983	protein dimerization activity

0.67	GO:0005802	trans-Golgi network
0.64	GO:0005829	cytosol
0.60	GO:0005654	nucleoplasm
0.42	GO:0005886	plasma membrane
0.37	GO:0000139	Golgi membrane
0.36	GO:0005643	nuclear pore
0.36	GO:0005813	centrosome

tr|T1G3A3|T1G3A3_HELRO
Uncharacterized protein
Search

0.84	Nicotinic acetylcholine receptor subunit type E

0.79	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.48	GO:0007271	synaptic transmission, cholinergic
0.43	GO:0017085	response to insecticide
0.39	GO:0006937	regulation of muscle contraction
0.38	GO:0060084	synaptic transmission involved in micturition
0.38	GO:0051971	positive regulation of transmission of nerve impulse
0.38	GO:0035095	behavioral response to nicotine
0.37	GO:0006939	smooth muscle contraction
0.37	GO:0001508	action potential

0.83	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0099600	transmembrane receptor activity
0.37	GO:0042166	acetylcholine binding
0.35	GO:0046982	protein heterodimerization activity
0.32	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.79	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.39	GO:0005892	acetylcholine-gated channel complex
0.36	GO:0031594	neuromuscular junction
0.35	GO:0043005	neuron projection

tr|T1G3A4|T1G3A4_HELRO
Uncharacterized protein
Search

0.65	GO:0035023	regulation of Rho protein signal transduction
0.61	GO:0006468	protein phosphorylation
0.57	GO:0065009	regulation of molecular function
0.52	GO:0030239	myofibril assembly
0.50	GO:0036309	protein localization to M-band
0.49	GO:0007527	adult somatic muscle development
0.45	GO:0031034	myosin filament assembly
0.45	GO:1905905	pharyngeal gland morphogenesis
0.44	GO:0045989	positive regulation of striated muscle contraction
0.41	GO:0040017	positive regulation of locomotion

0.66	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.62	GO:0004672	protein kinase activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0005523	tropomyosin binding
0.46	GO:0090736	MATH domain binding
0.45	GO:0019901	protein kinase binding
0.42	GO:0019902	phosphatase binding
0.39	GO:0070679	inositol 1,4,5 trisphosphate binding

0.53	GO:0031430	M band
0.37	GO:0005859	muscle myosin complex
0.37	GO:0030018	Z disc
0.30	GO:0031224	intrinsic component of membrane

tr|T1G3A5|T1G3A5_HELRO
Pyruvate kinase
Search

0.46	Pyruvate kinase PKM

0.70	GO:0006757	ATP generation from ADP
0.69	GO:0006090	pyruvate metabolic process
0.68	GO:0016052	carbohydrate catabolic process
0.67	GO:0019362	pyridine nucleotide metabolic process
0.42	GO:0032868	response to insulin
0.42	GO:0071375	cellular response to peptide hormone stimulus
0.40	GO:0012501	programmed cell death
0.37	GO:0001666	response to hypoxia
0.37	GO:0007584	response to nutrient
0.37	GO:0014870	response to muscle inactivity

0.78	GO:0004743	pyruvate kinase activity
0.77	GO:0030955	potassium ion binding
0.64	GO:0000287	magnesium ion binding
0.60	GO:0016301	kinase activity
0.41	GO:0045296	cadherin binding
0.36	GO:0070324	thyroid hormone binding
0.35	GO:0043531	ADP binding
0.35	GO:0023026	MHC class II protein complex binding
0.35	GO:0042802	identical protein binding
0.34	GO:0003950	NAD+ ADP-ribosyltransferase activity

0.42	GO:0043209	myelin sheath
0.40	GO:0005929	cilium
0.40	GO:0005829	cytosol
0.37	GO:1902912	pyruvate kinase complex
0.37	GO:0005634	nucleus
0.37	GO:0005739	mitochondrion
0.35	GO:0070062	extracellular exosome
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen
0.33	GO:0031012	extracellular matrix

0.78

EC:2.7.1.40

GO:0004743

tr|T1G3A6|T1G3A6_HELRO
Uncharacterized protein
Search

THOC7

0.94	THO complex subunit 7

0.70	GO:0006397	mRNA processing
0.64	GO:0046784	viral mRNA export from host cell nucleus
0.60	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.57	GO:0051028	mRNA transport
0.56	GO:0006405	RNA export from nucleus
0.38	GO:0008380	RNA splicing
0.36	GO:0006369	termination of RNA polymerase II transcription
0.35	GO:0031123	RNA 3'-end processing

0.36	GO:0003723	RNA binding
0.35	GO:0005515	protein binding

0.85	GO:0000445	THO complex part of transcription export complex
0.59	GO:0000781	chromosome, telomeric region
0.57	GO:0016607	nuclear speck
0.54	GO:0044454	nuclear chromosome part
0.51	GO:0005829	cytosol
0.30	GO:0016020	membrane

tr|T1G3A7|T1G3A7_HELRO
Anion exchange protein
Search

SLC4A10

0.64	Anion exchange protein (Fragment)

0.69	GO:0015698	inorganic anion transport
0.69	GO:0098656	anion transmembrane transport
0.46	GO:0030641	regulation of cellular pH
0.45	GO:0021860	pyramidal neuron development
0.44	GO:0035641	locomotory exploration behavior
0.44	GO:0048854	brain morphogenesis
0.43	GO:0015701	bicarbonate transport
0.43	GO:0035264	multicellular organism growth
0.42	GO:0007271	synaptic transmission, cholinergic
0.42	GO:0032228	regulation of synaptic transmission, GABAergic

0.82	GO:0005452	inorganic anion exchanger activity
0.47	GO:0015301	anion:anion antiporter activity
0.44	GO:0008510	sodium:bicarbonate symporter activity
0.40	GO:0015108	chloride transmembrane transporter activity
0.33	GO:0003700	DNA binding transcription factor activity
0.32	GO:0003677	DNA binding

0.45	GO:0097441	basal dendrite
0.45	GO:0097442	CA3 pyramidal cell dendrite
0.45	GO:0097440	apical dendrite
0.43	GO:0043025	neuronal cell body
0.43	GO:0016323	basolateral plasma membrane
0.39	GO:0005887	integral component of plasma membrane
0.37	GO:0044298	cell body membrane
0.33	GO:0005634	nucleus

tr|T1G3A8|T1G3A8_HELRO
Uncharacterized protein
Search

0.49	GO:0035023	regulation of Rho protein signal transduction
0.45	GO:0006468	protein phosphorylation
0.45	GO:0065009	regulation of molecular function
0.44	GO:0032501	multicellular organismal process
0.43	GO:0071711	basement membrane organization
0.43	GO:0009653	anatomical structure morphogenesis
0.42	GO:0031034	myosin filament assembly
0.41	GO:0061061	muscle structure development
0.41	GO:0031032	actomyosin structure organization
0.39	GO:0048468	cell development

0.56	GO:0005509	calcium ion binding
0.49	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.46	GO:0004672	protein kinase activity
0.42	GO:0032559	adenyl ribonucleotide binding
0.41	GO:0008144	drug binding
0.41	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0097493	structural molecule activity conferring elasticity
0.41	GO:0051371	muscle alpha-actinin binding
0.40	GO:0008307	structural constituent of muscle
0.39	GO:0051015	actin filament binding

0.51	GO:0005604	basement membrane
0.48	GO:0005938	cell cortex
0.48	GO:0030054	cell junction
0.42	GO:0031430	M band
0.41	GO:0005859	muscle myosin complex
0.40	GO:0030018	Z disc
0.38	GO:0070062	extracellular exosome
0.37	GO:0032154	cleavage furrow
0.36	GO:0032982	myosin filament
0.36	GO:0005887	integral component of plasma membrane

0.36

GO:0004725

tr|T1G3A9|T1G3A9_HELRO
Uncharacterized protein
Search

0.85	Voltage-dependent calcium channel beta subunit

0.77	GO:0070588	calcium ion transmembrane transport
0.42	GO:1901385	regulation of voltage-gated calcium channel activity
0.41	GO:0007528	neuromuscular junction development
0.40	GO:0007268	chemical synaptic transmission

0.82

GO:0005245

voltage-gated calcium channel activity

0.81

GO:0005891

voltage-gated calcium channel complex

tr|T1G3B0|T1G3B0_HELRO
Uncharacterized protein
Search

0.10	Homeobox protein LOX2 (Fragment)

0.61	GO:0007275	multicellular organism development
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.52	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis
0.51	GO:0009653	anatomical structure morphogenesis
0.51	GO:0002376	immune system process
0.47	GO:0006366	transcription by RNA polymerase II
0.47	GO:0048872	homeostasis of number of cells
0.46	GO:1902680	positive regulation of RNA biosynthetic process

0.63	GO:0043565	sequence-specific DNA binding
0.55	GO:0003700	DNA binding transcription factor activity
0.48	GO:0001012	RNA polymerase II regulatory region DNA binding
0.46	GO:0003690	double-stranded DNA binding
0.34	GO:0005515	protein binding
0.33	GO:0003723	RNA binding
0.33	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.32	GO:0009982	pseudouridine synthase activity
0.32	GO:0003887	DNA-directed DNA polymerase activity
0.32	GO:1901265	nucleoside phosphate binding

0.61	GO:0005634	nucleus
0.44	GO:0005829	cytosol
0.44	GO:0031974	membrane-enclosed lumen
0.40	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0004715

tr|T1G3B1|T1G3B1_HELRO
Uncharacterized protein
Search

0.94	RAB5-interacting protein isoform a

0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:0010468	regulation of gene expression

0.33

GO:0003677

DNA binding

0.41	GO:0005739	mitochondrion
0.33	GO:0005634	nucleus
0.30	GO:0044425	membrane part

tr|T1G3B2|T1G3B2_HELRO
Uncharacterized protein
Search

0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.72	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.59	GO:0038065	collagen-activated signaling pathway
0.46	GO:0038179	neurotrophin signaling pathway
0.39	GO:0048680	positive regulation of axon regeneration
0.37	GO:0048686	regulation of sprouting of injured axon
0.37	GO:2000251	positive regulation of actin cytoskeleton reorganization
0.37	GO:0050927	positive regulation of positive chemotaxis
0.37	GO:0032148	activation of protein kinase B activity
0.37	GO:0070306	lens fiber cell differentiation

0.76	GO:0004713	protein tyrosine kinase activity
0.73	GO:0019199	transmembrane receptor protein kinase activity
0.59	GO:0038064	collagen receptor activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.46	GO:0005030	neurotrophin receptor activity
0.37	GO:0002039	p53 binding
0.35	GO:0005509	calcium ion binding

0.51	GO:0005887	integral component of plasma membrane
0.36	GO:0043235	receptor complex
0.35	GO:0030424	axon
0.34	GO:0015935	small ribosomal subunit
0.33	GO:0005938	cell cortex

0.76

GO:0004713

tr|T1G3B3|T1G3B3_HELRO
Uncharacterized protein
Search

0.10	BDNF/NT-3 growth factors receptor

0.75	GO:0018108	peptidyl-tyrosine phosphorylation
0.66	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.40	GO:0006182	cGMP biosynthetic process
0.37	GO:0045464	R8 cell fate specification
0.37	GO:0045678	positive regulation of R7 cell differentiation
0.37	GO:0007465	R7 cell fate commitment
0.37	GO:0042067	establishment of ommatidial planar polarity
0.33	GO:0007601	visual perception
0.33	GO:0046777	protein autophosphorylation
0.33	GO:0051179	localization

0.75	GO:0004713	protein tyrosine kinase activity
0.67	GO:0019199	transmembrane receptor protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0004383	guanylate cyclase activity
0.33	GO:0022857	transmembrane transporter activity
0.32	GO:0008270	zinc ion binding
0.32	GO:0005102	receptor binding
0.32	GO:0003676	nucleic acid binding

0.35	GO:0044459	plasma membrane part
0.34	GO:0098533	ATPase dependent transmembrane transport complex
0.33	GO:0098796	membrane protein complex
0.33	GO:0098562	cytoplasmic side of membrane
0.32	GO:0019898	extrinsic component of membrane
0.31	GO:0044424	intracellular part

0.75

GO:0004713

tr|T1G3B4|T1G3B4_HELRO
Uncharacterized protein
Search

0.57	HIRA interacting protein 5

0.74	GO:0031163	metallo-sulfur cluster assembly
0.65	GO:0006790	sulfur compound metabolic process
0.63	GO:0051188	cofactor biosynthetic process
0.33	GO:0006470	protein dephosphorylation
0.32	GO:1901135	carbohydrate derivative metabolic process

0.64	GO:0051540	metal cluster binding
0.63	GO:0005506	iron ion binding
0.56	GO:0048037	cofactor binding
0.33	GO:0004721	phosphoprotein phosphatase activity
0.33	GO:0008483	transaminase activity
0.33	GO:0005515	protein binding
0.32	GO:0003676	nucleic acid binding
0.32	GO:0097367	carbohydrate derivative binding

0.40	GO:0005739	mitochondrion
0.40	GO:0005654	nucleoplasm
0.40	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0004721

tr|T1G3B5|T1G3B5_HELRO
Uncharacterized protein
Search

0.62	Fe-S cluster assembly

0.61	GO:0016226	iron-sulfur cluster assembly
0.59	GO:0007059	chromosome segregation
0.54	GO:0022402	cell cycle process
0.44	GO:1990067	intrachromosomal DNA recombination
0.43	GO:0009944	polarity specification of adaxial/abaxial axis
0.41	GO:2001022	positive regulation of response to DNA damage stimulus
0.39	GO:0042127	regulation of cell proliferation
0.39	GO:0051726	regulation of cell cycle
0.38	GO:0051301	cell division
0.36	GO:0006508	proteolysis

0.44	GO:0010209	vacuolar sorting signal binding
0.38	GO:0008234	cysteine-type peptidase activity

0.62	GO:0005876	spindle microtubule
0.41	GO:0016324	apical plasma membrane
0.36	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.38

GO:0008234

tr|T1G3B6|T1G3B6_HELRO
Uncharacterized protein
Search

0.61	GO:0006508	proteolysis
0.47	GO:0006898	receptor-mediated endocytosis
0.46	GO:0006030	chitin metabolic process
0.44	GO:0007614	short-term memory
0.43	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway
0.43	GO:0007616	long-term memory
0.42	GO:0042593	glucose homeostasis
0.34	GO:0030216	keratinocyte differentiation
0.34	GO:0006956	complement activation
0.33	GO:0007596	blood coagulation

0.69	GO:0004252	serine-type endopeptidase activity
0.51	GO:0005044	scavenger receptor activity
0.45	GO:0008061	chitin binding
0.36	GO:0005509	calcium ion binding
0.33	GO:0005057	signal transducer activity, downstream of receptor
0.33	GO:0042277	peptide binding
0.33	GO:0030695	GTPase regulator activity
0.33	GO:0070006	metalloaminopeptidase activity
0.32	GO:0008270	zinc ion binding

0.46	GO:0005576	extracellular region
0.36	GO:0005791	rough endoplasmic reticulum
0.34	GO:0046658	anchored component of plasma membrane
0.34	GO:0031982	vesicle
0.33	GO:0019897	extrinsic component of plasma membrane
0.33	GO:0005794	Golgi apparatus
0.30	GO:0016021	integral component of membrane

0.69

GO:0004252

tr|T1G3B7|T1G3B7_HELRO
Uncharacterized protein
Search

0.48

Syntaxin

0.69	GO:0006886	intracellular protein transport
0.68	GO:0016192	vesicle-mediated transport
0.68	GO:0061025	membrane fusion
0.65	GO:0017157	regulation of exocytosis
0.44	GO:0007340	acrosome reaction
0.44	GO:0097480	establishment of synaptic vesicle localization
0.43	GO:0099504	synaptic vesicle cycle
0.43	GO:0099643	signal release from synapse
0.43	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.43	GO:0048284	organelle fusion

0.81	GO:0005484	SNAP receptor activity
0.66	GO:0000149	SNARE binding
0.36	GO:0008146	sulfotransferase activity
0.33	GO:0003676	nucleic acid binding

0.45	GO:0005622	intracellular
0.42	GO:0098793	presynapse
0.42	GO:0012505	endomembrane system
0.41	GO:0031982	vesicle
0.40	GO:0030027	lamellipodium
0.40	GO:0016324	apical plasma membrane
0.39	GO:0005911	cell-cell junction
0.38	GO:0098796	membrane protein complex
0.35	GO:0098588	bounding membrane of organelle
0.30	GO:0016021	integral component of membrane

0.36

GO:0008146

tr|T1G3B8|T1G3B8_HELRO
Uncharacterized protein
Search

0.69	GO:0050808	synapse organization
0.68	GO:0050804	modulation of chemical synaptic transmission
0.62	GO:0007155	cell adhesion
0.47	GO:2000809	positive regulation of synaptic vesicle clustering
0.47	GO:0002087	regulation of respiratory gaseous exchange by neurological system process
0.46	GO:2000311	regulation of AMPA receptor activity
0.46	GO:0061002	negative regulation of dendritic spine morphogenesis
0.46	GO:1900451	positive regulation of glutamate receptor signaling pathway
0.46	GO:0060080	inhibitory postsynaptic potential
0.46	GO:2000331	regulation of terminal button organization

0.76	GO:0042043	neurexin family protein binding
0.44	GO:0097110	scaffold protein binding
0.43	GO:0052689	carboxylic ester hydrolase activity
0.38	GO:0004872	receptor activity
0.37	GO:0050839	cell adhesion molecule binding
0.34	GO:0042802	identical protein binding
0.34	GO:0008013	beta-catenin binding
0.34	GO:0001104	RNA polymerase II transcription cofactor activity
0.32	GO:0016491	oxidoreductase activity

0.64	GO:0045202	synapse
0.57	GO:0005887	integral component of plasma membrane
0.44	GO:0009986	cell surface
0.35	GO:0030139	endocytic vesicle
0.35	GO:0098590	plasma membrane region
0.35	GO:0030054	cell junction
0.34	GO:0043025	neuronal cell body
0.34	GO:0030425	dendrite
0.33	GO:0016592	mediator complex

0.43	EC:3.1.1 EC:3.1.1.1	GO:0052689
0.43	KEGG:R00630	GO:0052689

tr|T1G3B9|T1G3B9_HELRO
Uncharacterized protein
Search

IFT52

0.93	Intraflagellar transport protein 52

0.63	GO:0042073	intraciliary transport
0.58	GO:0042733	embryonic digit morphogenesis
0.57	GO:0001947	heart looping
0.57	GO:0070613	regulation of protein processing
0.57	GO:1905515	non-motile cilium assembly
0.57	GO:0001841	neural tube formation
0.57	GO:0050680	negative regulation of epithelial cell proliferation
0.56	GO:0007224	smoothened signaling pathway
0.56	GO:0009953	dorsal/ventral pattern formation
0.34	GO:0006468	protein phosphorylation

0.36	GO:0008022	protein C-terminus binding
0.35	GO:0004674	protein serine/threonine kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0016491	oxidoreductase activity

0.77	GO:0005929	cilium
0.60	GO:0044292	dendrite terminus
0.57	GO:0005815	microtubule organizing center
0.57	GO:0030992	intraciliary transport particle B
0.48	GO:0032838	plasma membrane bounded cell projection cytoplasm

0.35

GO:0004674

tr|T1G3C0|T1G3C0_HELRO
Uncharacterized protein
Search

0.41	Histone-lysine N-methyltransferase SETD1B

0.82	GO:0051568	histone H3-K4 methylation
0.42	GO:0018027	peptidyl-lysine dimethylation
0.42	GO:0046427	positive regulation of JAK-STAT cascade
0.42	GO:0018023	peptidyl-lysine trimethylation
0.34	GO:0006351	transcription, DNA-templated
0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression

0.79	GO:0018024	histone-lysine N-methyltransferase activity
0.54	GO:0003723	RNA binding
0.34	GO:0005515	protein binding

0.69	GO:0048188	Set1C/COMPASS complex
0.42	GO:0035327	transcriptionally active chromatin
0.42	GO:0000791	euchromatin
0.42	GO:0005700	polytene chromosome
0.41	GO:0005829	cytosol
0.36	GO:0016607	nuclear speck
0.30	GO:0031224	intrinsic component of membrane

0.79

GO:0018024

tr|T1G3C1|T1G3C1_HELRO
Uncharacterized protein
Search

0.68	GO:0036309	protein localization to M-band
0.66	GO:0007527	adult somatic muscle development
0.63	GO:0006468	protein phosphorylation
0.62	GO:0035023	regulation of Rho protein signal transduction
0.62	GO:0045214	sarcomere organization
0.55	GO:0065009	regulation of molecular function

0.64	GO:0004672	protein kinase activity
0.63	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.62	GO:0005523	tropomyosin binding
0.58	GO:0019901	protein kinase binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.63

GO:0031430

M band

tr|T1G3C2|T1G3C2_HELRO
Uncharacterized protein
Search

0.79	GO:0097194	execution phase of apoptosis
0.69	GO:0042981	regulation of apoptotic process
0.61	GO:0006508	proteolysis
0.53	GO:0097190	apoptotic signaling pathway
0.53	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
0.53	GO:0035234	ectopic germ cell programmed cell death
0.52	GO:0043068	positive regulation of programmed cell death
0.52	GO:0038034	signal transduction in absence of ligand
0.51	GO:0071260	cellular response to mechanical stimulus
0.48	GO:0009967	positive regulation of signal transduction

0.81	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis
0.47	GO:0019904	protein domain specific binding
0.46	GO:0042802	identical protein binding
0.37	GO:0002020	protease binding
0.36	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.36	GO:0005123	death receptor binding
0.35	GO:0008047	enzyme activator activity
0.34	GO:0032403	protein complex binding
0.34	GO:0004064	arylesterase activity

0.42	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm
0.38	GO:0031264	death-inducing signaling complex
0.35	GO:0098857	membrane microdomain
0.34	GO:1902494	catalytic complex
0.30	GO:0016021	integral component of membrane

0.36

EC:2.4.2.30

GO:0003950

tr|T1G3C3|T1G3C3_HELRO
Uncharacterized protein
Search

0.40	GO:0006413	translational initiation
0.37	GO:0006396	RNA processing
0.36	GO:0006369	termination of RNA polymerase II transcription
0.36	GO:0006379	mRNA cleavage
0.36	GO:0043631	RNA polyadenylation

0.58

GO:0003723

RNA binding

0.37	GO:0005654	nucleoplasm
0.34	GO:0043234	protein complex

tr|T1G3C4|T1G3C4_HELRO
Uncharacterized protein
Search

0.54	CCR4-NOT transcription complex subunit 2

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.41	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway
0.41	GO:2000036	regulation of stem cell population maintenance
0.41	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly
0.40	GO:0010558	negative regulation of macromolecule biosynthetic process
0.40	GO:0031327	negative regulation of cellular biosynthetic process
0.40	GO:0001829	trophectodermal cell differentiation
0.40	GO:0051172	negative regulation of nitrogen compound metabolic process

0.42	GO:0001226	RNA polymerase II transcription corepressor binding
0.40	GO:0004535	poly(A)-specific ribonuclease activity

0.61	GO:0005634	nucleus
0.43	GO:0030014	CCR4-NOT complex
0.41	GO:0000932	P-body
0.37	GO:0005829	cytosol
0.35	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.40

EC:3.1.13.4

GO:0004535

tr|T1G3C5|T1G3C5_HELRO
Uncharacterized protein
Search

0.61	GO:0006508	proteolysis
0.41	GO:0007596	blood coagulation
0.37	GO:0007276	gamete generation
0.37	GO:0045454	cell redox homeostasis
0.36	GO:0022900	electron transport chain
0.34	GO:0022412	cellular process involved in reproduction in multicellular organism
0.34	GO:0006898	receptor-mediated endocytosis
0.34	GO:0003006	developmental process involved in reproduction
0.34	GO:0048468	cell development
0.34	GO:0005975	carbohydrate metabolic process

0.69	GO:0004252	serine-type endopeptidase activity
0.39	GO:0005509	calcium ion binding
0.38	GO:0015035	protein disulfide oxidoreductase activity
0.36	GO:0009055	electron transfer activity
0.35	GO:0005044	scavenger receptor activity
0.35	GO:0030246	carbohydrate binding
0.35	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.33	GO:0005549	odorant binding
0.33	GO:0004531	deoxyribonuclease II activity
0.33	GO:0004181	metallocarboxypeptidase activity

0.38	GO:0005576	extracellular region
0.34	GO:0031225	anchored component of membrane
0.33	GO:0005886	plasma membrane
0.32	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.69

GO:0004252

tr|T1G3C6|T1G3C6_HELRO
Uncharacterized protein
Search

0.61	GO:0006508	proteolysis
0.35	GO:0006869	lipid transport
0.33	GO:0009249	protein lipoylation

0.78	GO:0004181	metallocarboxypeptidase activity
0.63	GO:0008270	zinc ion binding
0.36	GO:0005319	lipid transporter activity
0.33	GO:0033819	lipoyl(octanoyl) transferase activity
0.32	GO:0016874	ligase activity

0.37	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

0.78

EC:3.4.17

GO:0004181

tr|T1G3C7|T1G3C7_HELRO
Uncharacterized protein
Search

tr|T1G3C8|T1G3C8_HELRO
Uncharacterized protein
Search

0.58	GO:0035023	regulation of Rho protein signal transduction
0.56	GO:0006468	protein phosphorylation
0.52	GO:0065009	regulation of molecular function
0.44	GO:0036309	protein localization to M-band
0.43	GO:0055002	striated muscle cell development
0.43	GO:0009653	anatomical structure morphogenesis
0.43	GO:0007527	adult somatic muscle development
0.43	GO:0048010	vascular endothelial growth factor receptor signaling pathway
0.43	GO:0038084	vascular endothelial growth factor signaling pathway
0.42	GO:0031032	actomyosin structure organization

0.58	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.56	GO:0004672	protein kinase activity
0.49	GO:0030554	adenyl nucleotide binding
0.48	GO:0097367	carbohydrate derivative binding
0.48	GO:0008144	drug binding
0.48	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0005509	calcium ion binding
0.42	GO:0005523	tropomyosin binding
0.40	GO:0019901	protein kinase binding
0.39	GO:0004888	transmembrane signaling receptor activity

0.42	GO:0031430	M band
0.39	GO:0005604	basement membrane
0.38	GO:0005887	integral component of plasma membrane
0.37	GO:0015629	actin cytoskeleton
0.37	GO:0043235	receptor complex
0.36	GO:0005938	cell cortex
0.36	GO:0030054	cell junction
0.35	GO:0030018	Z disc
0.35	GO:0099513	polymeric cytoskeletal fiber
0.35	GO:0005634	nucleus

0.36	EC:1.11.1.7	GO:0004601
0.36	KEGG:R03532	GO:0004601

tr|T1G3C9|T1G3C9_HELRO
Uncharacterized protein
Search

0.54	GO:0046872	metal ion binding
0.32	GO:0003677	DNA binding

0.30

GO:0044425

membrane part

tr|T1G3D0|T1G3D0_HELRO
Uncharacterized protein
Search

0.53	GO:0055114	oxidation-reduction process
0.41	GO:0019373	epoxygenase P450 pathway
0.38	GO:0043651	linoleic acid metabolic process
0.37	GO:0034754	cellular hormone metabolic process
0.37	GO:0008202	steroid metabolic process
0.37	GO:0042446	hormone biosynthetic process
0.36	GO:0002165	instar larval or pupal development
0.36	GO:0042180	cellular ketone metabolic process
0.35	GO:1902653	secondary alcohol biosynthetic process
0.35	GO:0008258	head involution

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.65	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.38	GO:0047442	17-alpha-hydroxyprogesterone aldolase activity

0.34	GO:0005783	endoplasmic reticulum
0.30	GO:0016020	membrane

0.68

GO:0016705

tr|T1G3D1|T1G3D1_HELRO
Uncharacterized protein
Search

0.38	Cyclic nucleotide gated channel A beta subunit (Fragment)

0.58	GO:0034220	ion transmembrane transport
0.45	GO:0006812	cation transport
0.44	GO:0007601	visual perception
0.42	GO:0042391	regulation of membrane potential
0.39	GO:0034765	regulation of ion transmembrane transport
0.37	GO:0019935	cyclic-nucleotide-mediated signaling
0.37	GO:0010754	negative regulation of cGMP-mediated signaling
0.36	GO:0000413	protein peptidyl-prolyl isomerization
0.36	GO:0070482	response to oxygen levels
0.35	GO:0050893	sensory processing

0.67	GO:0005216	ion channel activity
0.51	GO:0022836	gated channel activity
0.45	GO:0008324	cation transmembrane transporter activity
0.45	GO:0015318	inorganic molecular entity transmembrane transporter activity
0.37	GO:0004692	cGMP-dependent protein kinase activity
0.36	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.36	GO:0030553	cGMP binding
0.33	GO:0008168	methyltransferase activity
0.33	GO:0008233	peptidase activity
0.33	GO:0005515	protein binding

0.39	GO:0005887	integral component of plasma membrane
0.39	GO:0017071	intracellular cyclic nucleotide activated cation channel complex
0.36	GO:0097730	non-motile cilium
0.36	GO:0097458	neuron part
0.35	GO:0044441	ciliary part
0.34	GO:0044297	cell body
0.32	GO:0005622	intracellular

0.37

EC:2.7.11.12

GO:0004692

tr|T1G3D2|T1G3D2_HELRO
Uncharacterized protein
Search

tr|T1G3D3|T1G3D3_HELRO
Uncharacterized protein
Search

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.48	GO:0007399	nervous system development
0.46	GO:0007423	sensory organ development
0.45	GO:0120036	plasma membrane bounded cell projection organization
0.44	GO:0030154	cell differentiation
0.44	GO:0007605	sensory perception of sound
0.44	GO:0007626	locomotory behavior
0.42	GO:0090176	microtubule cytoskeleton organization involved in establishment of planar polarity
0.42	GO:0044331	cell-cell adhesion mediated by cadherin
0.41	GO:0016336	establishment or maintenance of polarity of larval imaginal disc epithelium

0.70	GO:0005509	calcium ion binding
0.40	GO:0045296	cadherin binding
0.35	GO:0042802	identical protein binding
0.34	GO:0004872	receptor activity
0.34	GO:0046983	protein dimerization activity
0.33	GO:0004871	signal transducer activity

0.56	GO:0005886	plasma membrane
0.45	GO:0098858	actin-based cell projection
0.45	GO:0032421	stereocilium bundle
0.43	GO:0043005	neuron projection
0.41	GO:0005911	cell-cell junction
0.40	GO:0005912	adherens junction
0.37	GO:0044422	organelle part
0.37	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0030027	lamellipodium
0.35	GO:0005634	nucleus

tr|T1G3D4|T1G3D4_HELRO
Uncharacterized protein
Search

TRAPPC2

0.88	trafficking protein particle complex subunit 2

0.78	GO:0006888	ER to Golgi vesicle-mediated transport
0.40	GO:0001501	skeletal system development
0.36	GO:0006351	transcription, DNA-templated
0.36	GO:2001141	regulation of RNA biosynthetic process
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression
0.34	GO:0006901	vesicle coating
0.34	GO:0048199	vesicle targeting, to, from or within Golgi
0.34	GO:0048194	Golgi vesicle budding
0.33	GO:0006461	protein complex assembly

0.41	GO:0044325	ion channel binding
0.39	GO:0008134	transcription factor binding
0.34	GO:0017112	Rab guanyl-nucleotide exchange factor activity
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.49	GO:0005737	cytoplasm
0.42	GO:0030008	TRAPP complex
0.40	GO:0005634	nucleus
0.39	GO:0012505	endomembrane system
0.39	GO:0031974	membrane-enclosed lumen
0.36	GO:0044446	intracellular organelle part
0.33	GO:0098588	bounding membrane of organelle
0.30	GO:0016021	integral component of membrane

tr|T1G3D5|T1G3D5_HELRO
Uncharacterized protein
Search

0.76	Prostaglandin E synthase 2

0.68	GO:0045454	cell redox homeostasis
0.60	GO:0022900	electron transport chain
0.39	GO:0045893	positive regulation of transcription, DNA-templated
0.38	GO:0046903	secretion
0.35	GO:0046457	prostanoid biosynthetic process
0.35	GO:0071929	alpha-tubulin acetylation
0.35	GO:0006693	prostaglandin metabolic process
0.34	GO:0070507	regulation of microtubule cytoskeleton organization
0.34	GO:0048666	neuron development
0.33	GO:0002283	neutrophil activation involved in immune response

0.85	GO:0050220	prostaglandin-E synthase activity
0.71	GO:0015035	protein disulfide oxidoreductase activity
0.61	GO:0009055	electron transfer activity
0.38	GO:0016787	hydrolase activity
0.35	GO:0003677	DNA binding
0.35	GO:0016740	transferase activity
0.35	GO:0043295	glutathione binding
0.33	GO:0020037	heme binding
0.33	GO:0016829	lyase activity
0.32	GO:0003723	RNA binding

0.38	GO:0005829	cytosol
0.37	GO:0005739	mitochondrion
0.36	GO:0005634	nucleus
0.34	GO:0000139	Golgi membrane
0.34	GO:0005874	microtubule
0.33	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0035578	azurophil granule lumen
0.32	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.85	EC:5.3.99.3	GO:0050220
0.85	KEGG:R02265	GO:0050220

tr|T1G3D6|T1G3D6_HELRO
Uncharacterized protein
Search

CKAP5

0.71	Cytoskeleton-associated protein 5

0.85	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity
0.81	GO:0007098	centrosome cycle
0.79	GO:0007051	spindle organization
0.62	GO:0046785	microtubule polymerization
0.43	GO:0097711	ciliary basal body-plasma membrane docking
0.42	GO:0007019	microtubule depolymerization
0.41	GO:0000086	G2/M transition of mitotic cell cycle
0.41	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.40	GO:0007062	sister chromatid cohesion
0.39	GO:0051236	establishment of RNA localization

0.74	GO:0045296	cadherin binding
0.65	GO:0051010	microtubule plus-end binding

0.85	GO:0035371	microtubule plus-end
0.78	GO:0000922	spindle pole
0.77	GO:0000776	kinetochore
0.76	GO:0005813	centrosome
0.76	GO:0000930	gamma-tubulin complex
0.67	GO:0005730	nucleolus
0.52	GO:0005886	plasma membrane
0.40	GO:0000779	condensed chromosome, centromeric region
0.38	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|T1G3D7|T1G3D7_HELRO
Uncharacterized protein
Search

BECN1

0.87	Beclin 1 (Coiled-coil, myosin-like BCL2 interacting protein)

0.77	GO:0006914	autophagy
0.77	GO:0032465	regulation of cytokinesis
0.71	GO:0006897	endocytosis
0.54	GO:0009267	cellular response to starvation
0.52	GO:0007033	vacuole organization
0.52	GO:0045022	early endosome to late endosome transport
0.50	GO:0048731	system development
0.50	GO:0048869	cellular developmental process
0.50	GO:1902425	positive regulation of attachment of mitotic spindle microtubules to kinetochore
0.50	GO:0050435	amyloid-beta metabolic process

0.49	GO:0043548	phosphatidylinositol 3-kinase binding
0.46	GO:0031625	ubiquitin protein ligase binding
0.46	GO:0019901	protein kinase binding
0.45	GO:0042803	protein homodimerization activity
0.44	GO:0051020	GTPase binding

0.57	GO:0035032	phosphatidylinositol 3-kinase complex, class III
0.50	GO:0005776	autophagosome
0.49	GO:0031410	cytoplasmic vesicle
0.48	GO:0000407	phagophore assembly site
0.46	GO:0005802	trans-Golgi network
0.45	GO:0005783	endoplasmic reticulum
0.44	GO:0005829	cytosol
0.41	GO:0005739	mitochondrion
0.40	GO:0043234	protein complex
0.40	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network

tr|T1G3D8|T1G3D8_HELRO
Superoxide dismutase
Search

0.40	Superoxide dismutase

0.75	GO:0019430	removal of superoxide radicals
0.52	GO:0055114	oxidation-reduction process

0.77	GO:0004784	superoxide dismutase activity
0.54	GO:0046872	metal ion binding

0.77

EC:1.15.1.1

GO:0004784

tr|T1G3D9|T1G3D9_HELRO
Translocating chain-associated membrane protein
Search

0.84	Translocating chain-associated membrane protein 1

0.53	GO:0045184	establishment of protein localization
0.53	GO:0042886	amide transport
0.50	GO:0071702	organic substance transport
0.38	GO:0032964	collagen biosynthetic process
0.37	GO:0007029	endoplasmic reticulum organization
0.37	GO:0072657	protein localization to membrane
0.36	GO:0033365	protein localization to organelle
0.35	GO:0061024	membrane organization
0.33	GO:0046907	intracellular transport
0.33	GO:0009435	NAD biosynthetic process

0.34	GO:0005515	protein binding
0.33	GO:0003952	NAD+ synthase (glutamine-hydrolyzing) activity
0.33	GO:0004872	receptor activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.40	GO:0005783	endoplasmic reticulum
0.37	GO:1990075	periciliary membrane compartment
0.37	GO:0044292	dendrite terminus
0.37	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:6.3.5.1

GO:0003952

tr|T1G3E0|T1G3E0_HELRO
Synaptotagmin 1e
Search

0.62	Synaptotagmin I

0.81	GO:0099643	signal release from synapse
0.81	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.75	GO:0006836	neurotransmitter transport
0.71	GO:0001505	regulation of neurotransmitter levels
0.68	GO:0051649	establishment of localization in cell
0.45	GO:0060627	regulation of vesicle-mediated transport
0.43	GO:0017156	calcium ion regulated exocytosis
0.43	GO:0097479	synaptic vesicle localization
0.43	GO:0099003	vesicle-mediated transport in synapse
0.42	GO:0060024	rhythmic synaptic transmission

0.80	GO:0005544	calcium-dependent phospholipid binding
0.43	GO:0000149	SNARE binding
0.42	GO:0001786	phosphatidylserine binding
0.40	GO:0005509	calcium ion binding
0.39	GO:0042803	protein homodimerization activity
0.38	GO:0030276	clathrin binding
0.35	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity
0.34	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.33	GO:0046982	protein heterodimerization activity
0.33	GO:0005198	structural molecule activity

0.81	GO:0008021	synaptic vesicle
0.41	GO:0043195	terminal bouton
0.41	GO:0031594	neuromuscular junction
0.40	GO:0099501	exocytic vesicle membrane
0.35	GO:0031301	integral component of organelle membrane
0.35	GO:0030054	cell junction
0.35	GO:1990769	proximal neuron projection
0.35	GO:0031045	dense core granule
0.34	GO:0005883	neurofilament
0.34	GO:0005886	plasma membrane

0.35	EC:2.7.1.154	GO:0035005
0.35	KEGG:R05795	GO:0035005

tr|T1G3E1|T1G3E1_HELRO
Uncharacterized protein
Search

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.37	GO:1902680	positive regulation of RNA biosynthetic process
0.37	GO:0030154	cell differentiation
0.37	GO:0006366	transcription by RNA polymerase II
0.36	GO:0006904	vesicle docking involved in exocytosis
0.35	GO:0008544	epidermis development
0.35	GO:0007283	spermatogenesis
0.35	GO:0060429	epithelium development

0.65	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.38	GO:0001085	RNA polymerase II transcription factor binding
0.37	GO:0001012	RNA polymerase II regulatory region DNA binding
0.37	GO:0003682	chromatin binding
0.36	GO:0003690	double-stranded DNA binding

0.37	GO:0005667	transcription factor complex
0.35	GO:0005634	nucleus
0.32	GO:0005737	cytoplasm

tr|T1G3E2|T1G3E2_HELRO
Uncharacterized protein
Search

0.81	GO:0051568	histone H3-K4 methylation
0.49	GO:1900114	positive regulation of histone H3-K9 trimethylation
0.48	GO:0018990	ecdysis, chitin-based cuticle
0.48	GO:0035076	ecdysone receptor-mediated signaling pathway
0.48	GO:0008586	imaginal disc-derived wing vein morphogenesis
0.48	GO:0007474	imaginal disc-derived wing vein specification
0.43	GO:0045944	positive regulation of transcription by RNA polymerase II
0.37	GO:0040028	regulation of vulval development
0.35	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.34	GO:0007017	microtubule-based process

0.82	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.54	GO:0046872	metal ion binding
0.46	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.45	GO:0042393	histone binding
0.44	GO:0003682	chromatin binding
0.39	GO:0003677	DNA binding
0.36	GO:0035299	inositol pentakisphosphate 2-kinase activity
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.77	GO:0035097	histone methyltransferase complex
0.49	GO:0008230	ecdysone receptor holocomplex
0.46	GO:0005700	polytene chromosome
0.43	GO:0000790	nuclear chromatin
0.34	GO:0005874	microtubule
0.33	GO:0005886	plasma membrane
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.36	EC:2.7.1.158	GO:0035299
0.36	KEGG:R05202	GO:0035299

tr|T1G3E3|T1G3E3_HELRO
Uncharacterized protein
Search

SPNS1

0.90	Spinster homolog 1 (Drosophila)

0.54	GO:0055085	transmembrane transport
0.48	GO:0003376	sphingosine-1-phosphate signaling pathway
0.44	GO:0006869	lipid transport
0.41	GO:0040011	locomotion
0.35	GO:0032502	developmental process
0.35	GO:0090099	negative regulation of decapentaplegic signaling pathway
0.35	GO:2000026	regulation of multicellular organismal development
0.35	GO:0097352	autophagosome maturation
0.35	GO:0045477	regulation of nurse cell apoptotic process
0.34	GO:0045924	regulation of female receptivity

0.48	GO:0046624	sphingolipid transporter activity
0.33	GO:0005515	protein binding
0.32	GO:0046872	metal ion binding

0.46	GO:0005765	lysosomal membrane
0.43	GO:0031982	vesicle
0.36	GO:0031966	mitochondrial membrane
0.36	GO:0019866	organelle inner membrane
0.33	GO:0045202	synapse
0.33	GO:0012505	endomembrane system
0.30	GO:0031224	intrinsic component of membrane

tr|T1G3E4|T1G3E4_HELRO
Uncharacterized protein
Search

0.10	Transcription factor Sp3 (Fragment)

0.53	GO:0006357	regulation of transcription by RNA polymerase II
0.50	GO:0043353	enucleate erythrocyte differentiation
0.50	GO:0001779	natural killer cell differentiation
0.50	GO:1903131	mononuclear cell differentiation
0.50	GO:0030219	megakaryocyte differentiation
0.49	GO:0030851	granulocyte differentiation
0.49	GO:0060216	definitive hemopoiesis
0.49	GO:0048596	embryonic camera-type eye morphogenesis
0.49	GO:0060136	embryonic process involved in female pregnancy
0.48	GO:0030183	B cell differentiation

0.61	GO:0000987	proximal promoter sequence-specific DNA binding
0.54	GO:0003700	DNA binding transcription factor activity
0.47	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.46	GO:0003682	chromatin binding
0.34	GO:0003713	transcription coactivator activity
0.34	GO:0005515	protein binding
0.34	GO:0043023	ribosomal large subunit binding
0.33	GO:0043022	ribosome binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0032561	guanyl ribonucleotide binding

0.54	GO:0005634	nucleus
0.47	GO:0017053	transcriptional repressor complex
0.35	GO:0032993	protein-DNA complex
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0016887

tr|T1G3E5|T1G3E5_HELRO
Uncharacterized protein
Search

0.61	GO:0030150	protein import into mitochondrial matrix
0.59	GO:0009585	red, far-red light phototransduction
0.58	GO:0048511	rhythmic process
0.57	GO:0042752	regulation of circadian rhythm
0.53	GO:0006518	peptide metabolic process
0.52	GO:0043604	amide biosynthetic process
0.49	GO:0044267	cellular protein metabolic process
0.48	GO:1901566	organonitrogen compound biosynthetic process
0.48	GO:0010467	gene expression
0.47	GO:0009059	macromolecule biosynthetic process

0.56	GO:0003735	structural constituent of ribosome
0.37	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.36	GO:0016874	ligase activity

0.61	GO:0005744	mitochondrial inner membrane presequence translocase complex
0.59	GO:0005856	cytoskeleton
0.54	GO:0005840	ribosome
0.46	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.37

GO:0004553

tr|T1G3E6|T1G3E6_HELRO
Uncharacterized protein
Search

MYL9

0.81	Myosin regulatory light chain sqh

0.45	GO:0019749	cytoskeleton-dependent cytoplasmic transport, nurse cell to oocyte
0.45	GO:0031036	myosin II filament assembly
0.45	GO:0035191	nuclear axial expansion
0.45	GO:0060288	formation of a compartment boundary
0.45	GO:0060289	compartment boundary maintenance
0.44	GO:0090254	cell elongation involved in imaginal disc-derived wing morphogenesis
0.44	GO:0003384	apical constriction involved in gastrulation
0.44	GO:0035277	spiracle morphogenesis, open tracheal system
0.44	GO:0035159	regulation of tube length, open tracheal system
0.44	GO:0035317	imaginal disc-derived wing hair organization

0.70	GO:0005509	calcium ion binding
0.50	GO:0032036	myosin heavy chain binding
0.36	GO:0008307	structural constituent of muscle
0.35	GO:0045159	myosin II binding
0.34	GO:0019904	protein domain specific binding
0.34	GO:0046982	protein heterodimerization activity
0.33	GO:0004721	phosphoprotein phosphatase activity
0.33	GO:0004930	G-protein coupled receptor activity

0.49	GO:0016460	myosin II complex
0.45	GO:0106037	apicomedial cortex
0.45	GO:0035183	female germline ring canal inner rim
0.44	GO:0099512	supramolecular fiber
0.43	GO:0097517	contractile actin filament bundle
0.43	GO:0097610	cell surface furrow
0.43	GO:0042641	actomyosin
0.43	GO:0051233	spindle midzone
0.42	GO:0030496	midbody
0.42	GO:0032155	cell division site part

0.33

GO:0004721

tr|T1G3E7|T1G3E7_HELRO
Uncharacterized protein
Search

PINX1

0.79	PIN2/TERF1-interacting telomerase inhibitor 1

0.56	GO:0051974	negative regulation of telomerase activity
0.54	GO:1904744	positive regulation of telomeric DNA binding
0.54	GO:1904751	positive regulation of protein localization to nucleolus
0.53	GO:1902570	protein localization to nucleolus
0.52	GO:0070198	protein localization to chromosome, telomeric region
0.52	GO:0032211	negative regulation of telomere maintenance via telomerase
0.51	GO:0007004	telomere maintenance via telomerase
0.51	GO:0007080	mitotic metaphase plate congression
0.51	GO:0031397	negative regulation of protein ubiquitination
0.50	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle

0.57	GO:0010521	telomerase inhibitor activity
0.52	GO:0070034	telomerase RNA binding
0.45	GO:0044877	macromolecular complex binding
0.35	GO:0005515	protein binding
0.35	GO:0003677	DNA binding
0.34	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.33	GO:0001067	regulatory region nucleic acid binding

0.49	GO:0005730	nucleolus
0.49	GO:0000784	nuclear chromosome, telomeric region
0.48	GO:0000776	kinetochore
0.47	GO:0005819	spindle
0.37	GO:0000779	condensed chromosome, centromeric region
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|T1G3E8|T1G3E8_HELRO
Uncharacterized protein
Search

0.10	Myeloid/lymphoid or mixed-lineage leukemia 3b (Fragment)

0.77	GO:0051568	histone H3-K4 methylation
0.47	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway
0.46	GO:0043627	response to estrogen
0.45	GO:2001141	regulation of RNA biosynthetic process
0.45	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.44	GO:0010468	regulation of gene expression
0.44	GO:0008284	positive regulation of cell proliferation
0.42	GO:0051254	positive regulation of RNA metabolic process
0.42	GO:0010557	positive regulation of macromolecule biosynthetic process
0.42	GO:0031328	positive regulation of cellular biosynthetic process

0.79	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.54	GO:0046872	metal ion binding
0.43	GO:0044212	transcription regulatory region DNA binding
0.35	GO:0035299	inositol pentakisphosphate 2-kinase activity
0.34	GO:0005515	protein binding
0.34	GO:0003924	GTPase activity
0.34	GO:0005525	GTP binding
0.34	GO:0016746	transferase activity, transferring acyl groups
0.33	GO:0003723	RNA binding
0.33	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.74	GO:0035097	histone methyltransferase complex
0.36	GO:0071564	npBAF complex
0.33	GO:0005615	extracellular space
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.35	EC:2.7.1.158	GO:0035299
0.35	KEGG:R05202	GO:0035299

tr|T1G3E9|T1G3E9_HELRO
Flavin-containing monooxygenase
Search

0.27	Flavin-containing monooxygenase

0.53	GO:0055114	oxidation-reduction process
0.39	GO:0019758	glycosinolate biosynthetic process
0.39	GO:0019760	glucosinolate metabolic process
0.36	GO:0009753	response to jasmonic acid
0.36	GO:0009751	response to salicylic acid
0.36	GO:0009737	response to abscisic acid
0.35	GO:0006457	protein folding
0.34	GO:0015698	inorganic anion transport
0.33	GO:0032259	methylation

0.78	GO:0004499	N,N-dimethylaniline monooxygenase activity
0.70	GO:0050661	NADP binding
0.66	GO:0050660	flavin adenine dinucleotide binding
0.37	GO:0080106	7-methylthiopropyl glucosinolate S-oxygenase activity
0.37	GO:0080104	5-methylthiopropyl glucosinolate S-oxygenase activity
0.37	GO:0080102	3-methylthiopropyl glucosinolate S-oxygenase activity
0.37	GO:0080103	4-methylthiopropyl glucosinolate S-oxygenase activity
0.37	GO:0080107	8-methylthiopropyl glucosinolate S-oxygenase activity
0.35	GO:0005452	inorganic anion exchanger activity
0.35	GO:0004040	amidase activity

0.36	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.78

EC:1.14.13.8

GO:0004499

tr|T1G3F0|T1G3F0_HELRO
Gamma-glutamylcyclotransferase
Search

0.44	Gamma-glutamylcyclotransferase

0.79	GO:0006751	glutathione catabolic process
0.36	GO:0010288	response to lead ion
0.35	GO:0046686	response to cadmium ion
0.33	GO:0006351	transcription, DNA-templated
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression
0.33	GO:0006468	protein phosphorylation
0.33	GO:0006629	lipid metabolic process

0.81	GO:0003839	gamma-glutamylcyclotransferase activity
0.56	GO:0016829	lyase activity
0.33	GO:0003700	DNA binding transcription factor activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0032561	guanyl ribonucleotide binding
0.33	GO:0003677	DNA binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding

0.35	GO:0005667	transcription factor complex
0.35	GO:0055120	striated muscle dense body
0.34	GO:0005829	cytosol
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.81

EC:2.3.2.4

GO:0003839

tr|T1G3F1|T1G3F1_HELRO
Uncharacterized protein
Search

HIKESHI

0.91	Hikeshi, heat shock protein nuclear import factor

0.72	GO:0006606	protein import into nucleus
0.71	GO:0034605	cellular response to heat
0.62	GO:0030324	lung development
0.61	GO:0007030	Golgi organization
0.39	GO:0006086	acetyl-CoA biosynthetic process from pyruvate
0.38	GO:0006099	tricarboxylic acid cycle
0.38	GO:0006020	inositol metabolic process
0.36	GO:0006508	proteolysis
0.36	GO:0032259	methylation

0.77	GO:0030544	Hsp70 protein binding
0.63	GO:0008565	protein transporter activity
0.42	GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
0.39	GO:0004738	pyruvate dehydrogenase activity
0.38	GO:0030976	thiamine pyrophosphate binding
0.38	GO:0061608	nuclear import signal receptor activity
0.38	GO:0008242	omega peptidase activity
0.36	GO:0008168	methyltransferase activity
0.34	GO:0070001	aspartic-type peptidase activity
0.34	GO:0004175	endopeptidase activity

0.61	GO:0005829	cytosol
0.56	GO:0005634	nucleus
0.36	GO:0005840	ribosome
0.36	GO:0012505	endomembrane system
0.35	GO:0031967	organelle envelope

0.42

EC:1.2.4

GO:0016624

tr|T1G3F2|T1G3F2_HELRO
Uncharacterized protein
Search

0.57	Dual specificity protein phosphatase 19

0.72	GO:0035335	peptidyl-tyrosine dephosphorylation
0.46	GO:0000188	inactivation of MAPK activity
0.38	GO:2000786	positive regulation of autophagosome assembly
0.37	GO:0030476	ascospore wall assembly
0.37	GO:0019933	cAMP-mediated signaling
0.36	GO:0000027	ribosomal large subunit assembly
0.35	GO:0007062	sister chromatid cohesion
0.35	GO:0000724	double-strand break repair via homologous recombination
0.33	GO:0016310	phosphorylation

0.79	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.72	GO:0004725	protein tyrosine phosphatase activity
0.47	GO:0033549	MAP kinase phosphatase activity
0.33	GO:0016301	kinase activity
0.33	GO:0003723	RNA binding

0.37	GO:0010494	cytoplasmic stress granule
0.36	GO:0030687	preribosome, large subunit precursor
0.35	GO:0030915	Smc5-Smc6 complex
0.34	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.79

GO:0008138

tr|T1G3F3|T1G3F3_HELRO
Uncharacterized protein
Search

EPRS

0.89	Bifunctional aminoacyl-tRNA synthetase

0.78	GO:0006433	prolyl-tRNA aminoacylation
0.74	GO:0006424	glutamyl-tRNA aminoacylation
0.49	GO:0071346	cellular response to interferon-gamma
0.46	GO:0017148	negative regulation of translation
0.34	GO:0016485	protein processing
0.33	GO:0006461	protein complex assembly
0.33	GO:0006511	ubiquitin-dependent protein catabolic process
0.32	GO:0051276	chromosome organization

0.78	GO:0004827	proline-tRNA ligase activity
0.75	GO:0004818	glutamate-tRNA ligase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0035613	RNA stem-loop binding
0.45	GO:0042803	protein homodimerization activity
0.45	GO:0051020	GTPase binding
0.41	GO:0008270	zinc ion binding
0.33	GO:0070003	threonine-type peptidase activity

0.51	GO:0097452	GAIT complex
0.51	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex
0.49	GO:0005737	cytoplasm
0.41	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0019773	proteasome core complex, alpha-subunit complex
0.32	GO:0005634	nucleus
0.32	GO:0005694	chromosome
0.30	GO:0016020	membrane

0.78

EC:6.1.1.15

GO:0004827

tr|T1G3F4|T1G3F4_HELRO
Protein kinase C
Search

0.11	Calcium-independent protein kinase C

0.63	GO:0006468	protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.42	GO:0034389	lipid particle organization
0.42	GO:0007611	learning or memory
0.42	GO:0009950	dorsal/ventral axis specification
0.42	GO:0045471	response to ethanol
0.41	GO:0007030	Golgi organization
0.41	GO:0018209	peptidyl-serine modification
0.41	GO:0008285	negative regulation of cell proliferation
0.36	GO:0050893	sensory processing

0.84	GO:0004697	protein kinase C activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0046872	metal ion binding

0.45	GO:0005622	intracellular
0.35	GO:0098793	presynapse
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.84

EC:2.7.11.13

GO:0004697

tr|T1G3F5|T1G3F5_HELRO
Uncharacterized protein
Search

0.55	GO:0055085	transmembrane transport
0.40	GO:0015711	organic anion transport
0.38	GO:0042908	xenobiotic transport
0.36	GO:0015893	drug transport
0.35	GO:0015865	purine nucleotide transport
0.33	GO:0042144	vacuole fusion, non-autophagic
0.33	GO:0015691	cadmium ion transport
0.32	GO:0015849	organic acid transport
0.32	GO:0055114	oxidation-reduction process
0.31	GO:0042886	amide transport

0.65	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0008514	organic anion transmembrane transporter activity
0.38	GO:0042910	xenobiotic transmembrane transporter activity
0.36	GO:0015238	drug transmembrane transporter activity
0.35	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.35	GO:0015216	purine nucleotide transmembrane transporter activity
0.33	GO:0015086	cadmium ion transmembrane transporter activity

0.41	GO:0005739	mitochondrion
0.39	GO:0005887	integral component of plasma membrane
0.37	GO:0016323	basolateral plasma membrane
0.33	GO:0000329	fungal-type vacuole membrane

0.35

GO:0032440

tr|T1G3F6|T1G3F6_HELRO
Uncharacterized protein
Search

PRC1

0.64	Protein regulator of cytokinesis 1

0.83	GO:0001578	microtubule bundle formation
0.72	GO:0000910	cytokinesis
0.47	GO:0008284	positive regulation of cell proliferation
0.47	GO:0032465	regulation of cytokinesis
0.39	GO:0006904	vesicle docking involved in exocytosis
0.35	GO:0000022	mitotic spindle elongation
0.34	GO:0036211	protein modification process
0.33	GO:0044267	cellular protein metabolic process

0.74	GO:0008017	microtubule binding
0.50	GO:0019894	kinesin binding
0.47	GO:0019901	protein kinase binding
0.36	GO:0042802	identical protein binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.69	GO:0005856	cytoskeleton
0.49	GO:0070938	contractile ring
0.49	GO:0030496	midbody
0.41	GO:0005634	nucleus
0.40	GO:0044446	intracellular organelle part
0.35	GO:0099512	supramolecular fiber
0.33	GO:0005829	cytosol

tr|T1G3F7|T1G3F7_HELRO
Uncharacterized protein
Search

tr|T1G3F8|T1G3F8_HELRO
Uncharacterized protein
Search

0.45	GO:0070293	renal absorption
0.44	GO:0048082	regulation of adult chitin-containing cuticle pigmentation
0.43	GO:0006955	immune response
0.43	GO:0040003	chitin-based cuticle development
0.43	GO:0006897	endocytosis
0.42	GO:0030100	regulation of endocytosis
0.38	GO:0071391	cellular response to estrogen stimulus
0.37	GO:1904252	negative regulation of bile acid metabolic process
0.37	GO:0072376	protein activation cascade
0.37	GO:0070857	regulation of bile acid biosynthetic process

0.63	GO:0005509	calcium ion binding
0.39	GO:0038024	cargo receptor activity
0.38	GO:0004252	serine-type endopeptidase activity
0.35	GO:0015248	sterol transporter activity
0.34	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.34	GO:0008061	chitin binding
0.33	GO:0005249	voltage-gated potassium channel activity
0.33	GO:0004930	G-protein coupled receptor activity

0.46	GO:0005579	membrane attack complex
0.42	GO:0016324	apical plasma membrane
0.39	GO:0005794	Golgi apparatus
0.36	GO:0005576	extracellular region
0.35	GO:0031410	cytoplasmic vesicle
0.35	GO:1990777	lipoprotein particle
0.34	GO:0005905	clathrin-coated pit
0.34	GO:0005829	cytosol
0.33	GO:0012506	vesicle membrane
0.33	GO:0008076	voltage-gated potassium channel complex

0.38

GO:0004252

tr|T1G3F9|T1G3F9_HELRO
Uncharacterized protein
Search

0.44	GO:0036049	peptidyl-lysine desuccinylation
0.44	GO:0036046	protein demalonylation
0.42	GO:0006476	protein deacetylation
0.37	GO:0071392	cellular response to estradiol stimulus
0.37	GO:0045648	positive regulation of erythrocyte differentiation
0.36	GO:0035335	peptidyl-tyrosine dephosphorylation

0.45	GO:0070403	NAD+ binding
0.44	GO:0036055	protein-succinyllysine desuccinylase activity
0.44	GO:0036054	protein-malonyllysine demalonylase activity
0.42	GO:0034979	NAD-dependent protein deacetylase activity
0.38	GO:0008270	zinc ion binding
0.36	GO:0004725	protein tyrosine phosphatase activity

0.38	GO:0005739	mitochondrion
0.36	GO:0031968	organelle outer membrane
0.30	GO:0016021	integral component of membrane

0.36

GO:0004725

tr|T1G3G0|T1G3G0_HELRO
Uncharacterized protein
Search

tr|T1G3G1|T1G3G1_HELRO
Uncharacterized protein
Search

0.45	GO:0007165	signal transduction
0.43	GO:1902532	negative regulation of intracellular signal transduction
0.43	GO:0050707	regulation of cytokine secretion
0.43	GO:0002218	activation of innate immune response
0.43	GO:0006954	inflammatory response
0.43	GO:0045859	regulation of protein kinase activity
0.42	GO:0007417	central nervous system development
0.42	GO:0001933	negative regulation of protein phosphorylation
0.42	GO:0070430	positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway
0.42	GO:0045087	innate immune response

0.45	GO:0004888	transmembrane signaling receptor activity
0.45	GO:0016500	protein-hormone receptor activity
0.41	GO:0001875	lipopolysaccharide receptor activity
0.41	GO:0004860	protein kinase inhibitor activity
0.40	GO:0001530	lipopolysaccharide binding
0.39	GO:0005199	structural constituent of cell wall
0.39	GO:0004672	protein kinase activity
0.39	GO:0003727	single-stranded RNA binding
0.38	GO:0046982	protein heterodimerization activity
0.38	GO:0005509	calcium ion binding

0.41	GO:0046696	lipopolysaccharide receptor complex
0.40	GO:0009897	external side of plasma membrane
0.39	GO:0005887	integral component of plasma membrane
0.39	GO:0048471	perinuclear region of cytoplasm

tr|T1G3G2|T1G3G2_HELRO
Uncharacterized protein
Search

0.72	Tetratricopeptide repeat protein 21B (Fragment)

0.71	GO:0035721	intraciliary retrograde transport
0.70	GO:0061512	protein localization to cilium
0.60	GO:0021798	forebrain dorsal/ventral pattern formation
0.58	GO:0021591	ventricular system development
0.57	GO:0008589	regulation of smoothened signaling pathway
0.56	GO:0007224	smoothened signaling pathway
0.54	GO:0007369	gastrulation
0.50	GO:0006357	regulation of transcription by RNA polymerase II
0.40	GO:0033566	gamma-tubulin complex localization
0.36	GO:0006486	protein glycosylation

0.51	GO:0042802	identical protein binding
0.36	GO:0030246	carbohydrate binding
0.35	GO:0016757	transferase activity, transferring glycosyl groups
0.35	GO:0004252	serine-type endopeptidase activity
0.34	GO:0008092	cytoskeletal protein binding
0.34	GO:0019900	kinase binding
0.33	GO:0038132	neuregulin binding
0.33	GO:0031994	insulin-like growth factor I binding
0.33	GO:0001664	G-protein coupled receptor binding
0.33	GO:0004462	lactoylglutathione lyase activity

0.71	GO:0030991	intraciliary transport particle A
0.62	GO:0005929	cilium
0.52	GO:0000790	nuclear chromatin
0.39	GO:0008274	gamma-tubulin ring complex
0.36	GO:0005794	Golgi apparatus
0.33	GO:0030056	hemidesmosome
0.33	GO:0008305	integrin complex
0.33	GO:0031252	cell leading edge
0.33	GO:0009986	cell surface
0.32	GO:0005789	endoplasmic reticulum membrane

0.35	EC:2.4	GO:0016757
0.33	KEGG:R02530	GO:0004462

tr|T1G3G3|T1G3G3_HELRO
Uncharacterized protein
Search

tr|T1G3G4|T1G3G4_HELRO
Uncharacterized protein
Search

GORASP2

0.66	Golgi reassembly-stacking protein 2

0.65	GO:0007030	Golgi organization
0.35	GO:0006468	protein phosphorylation

0.39	GO:0004692	cGMP-dependent protein kinase activity
0.37	GO:0005515	protein binding
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0097367	carbohydrate derivative binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.71	GO:0005794	Golgi apparatus
0.41	GO:0098588	bounding membrane of organelle
0.40	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.39

EC:2.7.11.12

GO:0004692

tr|T1G3G5|T1G3G5_HELRO
Uncharacterized protein
Search

0.48	Homeobox protein fushi tarazu

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.46	GO:0007275	multicellular organism development
0.37	GO:0007548	sex differentiation
0.36	GO:1902680	positive regulation of RNA biosynthetic process
0.36	GO:0048337	positive regulation of mesodermal cell fate specification
0.36	GO:0009653	anatomical structure morphogenesis
0.36	GO:1902679	negative regulation of RNA biosynthetic process
0.35	GO:0050679	positive regulation of epithelial cell proliferation

0.63	GO:0043565	sequence-specific DNA binding
0.43	GO:0003700	DNA binding transcription factor activity
0.35	GO:0008134	transcription factor binding
0.35	GO:0001012	RNA polymerase II regulatory region DNA binding
0.34	GO:0003690	double-stranded DNA binding
0.33	GO:0004000	adenosine deaminase activity

0.61	GO:0005634	nucleus
0.34	GO:0005667	transcription factor complex
0.33	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:3.5.4.4

GO:0004000

tr|T1G3G6|T1G3G6_HELRO
Elongation of very long chain fatty acids protein
Search

ELO-3

0.55	Elongation of very long chain fatty acids protein 6

0.70	GO:0006633	fatty acid biosynthetic process
0.44	GO:0000038	very long-chain fatty acid metabolic process
0.41	GO:0030148	sphingolipid biosynthetic process
0.36	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process
0.36	GO:0033559	unsaturated fatty acid metabolic process
0.33	GO:0001676	long-chain fatty acid metabolic process

0.82	GO:0102756	very-long-chain 3-ketoacyl-CoA synthase activity
0.82	GO:0102338	3-oxo-lignoceronyl-CoA synthase activity
0.82	GO:0102336	3-oxo-arachidoyl-CoA synthase activity
0.82	GO:0102337	3-oxo-cerotoyl-CoA synthase activity
0.45	GO:0009922	fatty acid elongase activity
0.32	GO:0003723	RNA binding

0.41	GO:0005783	endoplasmic reticulum
0.40	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.39	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.82

EC:2.3.1.199

GO:0102338

tr|T1G3G7|T1G3G7_HELRO
Uncharacterized protein
Search

tr|T1G3G8|T1G3G8_HELRO
Uncharacterized protein
Search

0.47	periodic tryptophan protein 1 homolog

0.76	GO:0030723	ovarian fusome organization
0.75	GO:0036098	male germ-line stem cell population maintenance
0.70	GO:0008584	male gonad development
0.69	GO:0030707	ovarian follicle cell development
0.52	GO:0006364	rRNA processing
0.49	GO:0060255	regulation of macromolecule metabolic process
0.47	GO:0036099	female germ-line stem cell population maintenance
0.44	GO:0016573	histone acetylation
0.37	GO:0032259	methylation

0.69	GO:0031490	chromatin DNA binding
0.45	GO:0004402	histone acetyltransferase activity
0.37	GO:0008168	methyltransferase activity

0.71	GO:0035327	transcriptionally active chromatin
0.60	GO:0005634	nucleus
0.51	GO:0031974	membrane-enclosed lumen

0.45

GO:0004402

tr|T1G3G9|T1G3G9_HELRO
Uncharacterized protein
Search

0.58	GO:0030277	maintenance of gastrointestinal epithelium
0.45	GO:0030154	cell differentiation
0.45	GO:0007399	nervous system development
0.40	GO:0036438	maintenance of lens transparency
0.39	GO:0006030	chitin metabolic process
0.39	GO:0048015	phosphatidylinositol-mediated signaling
0.39	GO:0010466	negative regulation of peptidase activity
0.37	GO:0048583	regulation of response to stimulus
0.36	GO:0007431	salivary gland development
0.36	GO:0010477	response to sulfur dioxide

0.39	GO:0008061	chitin binding
0.39	GO:0030414	peptidase inhibitor activity
0.36	GO:0005179	hormone activity
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.62	GO:0070701	mucus layer
0.40	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.35	GO:0005796	Golgi lumen
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1G3H0|T1G3H0_HELRO
Uncharacterized protein
Search

0.70	GO:0007275	multicellular organism development
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.43	GO:0051254	positive regulation of RNA metabolic process
0.43	GO:0010557	positive regulation of macromolecule biosynthetic process
0.43	GO:0031328	positive regulation of cellular biosynthetic process
0.34	GO:0120035	regulation of plasma membrane bounded cell projection organization
0.34	GO:0051960	regulation of nervous system development

0.68	GO:0046983	protein dimerization activity
0.59	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.54	GO:0046872	metal ion binding
0.44	GO:0001067	regulatory region nucleic acid binding
0.36	GO:0008134	transcription factor binding
0.33	GO:0035035	histone acetyltransferase binding
0.33	GO:0005248	voltage-gated sodium channel activity
0.33	GO:0042802	identical protein binding

0.61	GO:0005634	nucleus
0.33	GO:0001518	voltage-gated sodium channel complex
0.33	GO:0000785	chromatin
0.32	GO:0043233	organelle lumen

tr|T1G3H1|T1G3H1_HELRO
Uncharacterized protein
Search

tr|T1G3H2|T1G3H2_HELRO
Uncharacterized protein
Search

DCTN6

0.92	Dynactin subunit 6

0.36	GO:0007052	mitotic spindle organization
0.35	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.34	GO:0006888	ER to Golgi vesicle-mediated transport
0.34	GO:0007005	mitochondrion organization
0.33	GO:0008610	lipid biosynthetic process

0.37	GO:0070840	dynein complex binding
0.30	GO:0003824	catalytic activity

0.79	GO:0005869	dynactin complex
0.52	GO:0005813	centrosome
0.40	GO:0000777	condensed chromosome kinetochore
0.34	GO:0005737	cytoplasm
0.32	GO:0043227	membrane-bounded organelle

tr|T1G3H3|T1G3H3_HELRO
Uncharacterized protein
Search

EFHC2

0.81	EF-hand domain containing 2

0.64	GO:1990823	response to leukemia inhibitory factor
0.60	GO:0071345	cellular response to cytokine stimulus

0.62	GO:0005509	calcium ion binding
0.35	GO:0005515	protein binding

0.37	GO:0031514	motile cilium
0.36	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

tr|T1G3H4|T1G3H4_HELRO
Uncharacterized protein
Search

0.86	LRP2-binding protein-like

0.30

GO:0044425

membrane part

tr|T1G3H5|T1G3H5_HELRO
Uncharacterized protein
Search

tr|T1G3H6|T1G3H6_HELRO
Uncharacterized protein
Search

0.75	NHP2 ribonucleoprotein homolog (yeast)

0.48

GO:0006412

translation

0.53	GO:0003723	RNA binding
0.51	GO:0003735	structural constituent of ribosome

0.65	GO:0005730	nucleolus
0.49	GO:0005840	ribosome

tr|T1G3H7|T1G3H7_HELRO
Uncharacterized protein
Search

tr|T1G3H8|T1G3H8_HELRO
Uncharacterized protein
Search

tr|T1G3H9|T1G3H9_HELRO
Uncharacterized protein
Search

0.38	Bruton agammaglobulinemia tyrosine kinase

0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.48	GO:0046777	protein autophosphorylation
0.47	GO:0033008	positive regulation of mast cell activation involved in immune response
0.47	GO:0043302	positive regulation of leukocyte degranulation
0.47	GO:0002888	positive regulation of myeloid leukocyte mediated immunity
0.46	GO:0043304	regulation of mast cell degranulation
0.46	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity
0.46	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling
0.46	GO:0050764	regulation of phagocytosis
0.45	GO:0050715	positive regulation of cytokine secretion

0.77	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0034988	Fc-gamma receptor I complex binding
0.46	GO:0001784	phosphotyrosine residue binding
0.43	GO:0019901	protein kinase binding
0.35	GO:0005328	neurotransmitter:sodium symporter activity
0.34	GO:0051427	hormone receptor binding

0.46	GO:0016235	aggresome
0.45	GO:0032587	ruffle membrane
0.43	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.42	GO:0015629	actin cytoskeleton
0.35	GO:0005829	cytosol
0.35	GO:0005758	mitochondrial intermembrane space
0.34	GO:0034774	secretory granule lumen
0.34	GO:0070062	extracellular exosome
0.33	GO:0005815	microtubule organizing center
0.33	GO:0005743	mitochondrial inner membrane

0.77

GO:0004715

tr|T1G3I0|T1G3I0_HELRO
Uncharacterized protein
Search

0.90	Salivary selenoprotein M

tr|T1G3I1|T1G3I1_HELRO
Uncharacterized protein
Search

BRSK2

0.83	BR serine/threonine-protein kinase 2

0.63	GO:0006468	protein phosphorylation
0.44	GO:0050808	synapse organization
0.43	GO:0018209	peptidyl-serine modification
0.43	GO:0007409	axonogenesis
0.43	GO:0007163	establishment or maintenance of cell polarity
0.41	GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus
0.41	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
0.41	GO:0006487	protein N-linked glycosylation
0.40	GO:0000086	G2/M transition of mitotic cell cycle
0.40	GO:0036503	ERAD pathway

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0051117	ATPase binding
0.40	GO:0019901	protein kinase binding
0.37	GO:0000287	magnesium ion binding
0.35	GO:0030983	mismatched DNA binding
0.34	GO:0060590	ATPase regulator activity

0.40	GO:0005813	centrosome
0.38	GO:0030425	dendrite
0.38	GO:0030424	axon
0.38	GO:0005634	nucleus
0.38	GO:0045202	synapse
0.38	GO:0005783	endoplasmic reticulum
0.34	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0030054	cell junction
0.30	GO:0016020	membrane

tr|T1G3I2|T1G3I2_HELRO
Uncharacterized protein
Search

tr|T1G3I3|T1G3I3_HELRO
Uncharacterized protein
Search

0.10	Kinase domain protein

0.63	GO:0006468	protein phosphorylation
0.46	GO:0031028	septation initiation signaling
0.45	GO:1902542	regulation of protein localization to mitotic spindle pole body
0.41	GO:0032147	activation of protein kinase activity
0.41	GO:0031098	stress-activated protein kinase signaling cascade
0.39	GO:0042981	regulation of apoptotic process
0.37	GO:0043408	regulation of MAPK cascade
0.36	GO:0030036	actin cytoskeleton organization
0.36	GO:0007266	Rho protein signal transduction
0.35	GO:0071902	positive regulation of protein serine/threonine kinase activity

0.64	GO:0004672	protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0048365	Rac GTPase binding
0.35	GO:0005057	signal transducer activity, downstream of receptor
0.33	GO:0030246	carbohydrate binding
0.33	GO:0008146	sulfotransferase activity
0.33	GO:0050660	flavin adenine dinucleotide binding

0.44	GO:0044732	mitotic spindle pole body
0.34	GO:0005737	cytoplasm
0.33	GO:0005634	nucleus
0.33	GO:0000131	incipient cellular bud site
0.33	GO:0043332	mating projection tip
0.33	GO:1990385	meiotic spindle midzone
0.33	GO:0031616	spindle pole centrosome
0.33	GO:0032133	chromosome passenger complex
0.33	GO:0000939	condensed chromosome inner kinetochore
0.33	GO:1990023	mitotic spindle midzone

0.33

GO:0008146

tr|T1G3I4|T1G3I4_HELRO
Uncharacterized protein
Search

0.54	CHY zinc finger domain-containing protein

0.34	GO:0016192	vesicle-mediated transport
0.33	GO:0032940	secretion by cell
0.32	GO:0006518	peptide metabolic process
0.32	GO:0098657	import into cell
0.32	GO:0055114	oxidation-reduction process

0.62	GO:0008270	zinc ion binding
0.39	GO:0003677	DNA binding
0.34	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
0.33	GO:0005507	copper ion binding
0.32	GO:0005044	scavenger receptor activity
0.32	GO:0003723	RNA binding

0.34	GO:0000145	exocyst
0.33	GO:0005634	nucleus
0.30	GO:0044425	membrane part

0.34

EC:1.14.17

GO:0016715

tr|T1G3I5|T1G3I5_HELRO
Uncharacterized protein
Search

0.43	GO:1901215	negative regulation of neuron death
0.37	GO:0006357	regulation of transcription by RNA polymerase II
0.34	GO:0016579	protein deubiquitination
0.34	GO:0006511	ubiquitin-dependent protein catabolic process

0.54	GO:0003677	DNA binding
0.38	GO:0001067	regulatory region nucleic acid binding
0.34	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity

0.60	GO:0005634	nucleus
0.40	GO:0000785	chromatin
0.39	GO:0031974	membrane-enclosed lumen
0.38	GO:1902494	catalytic complex
0.30	GO:0016020	membrane

0.34

EC:3.4.19.12

GO:0036459

tr|T1G3I6|T1G3I6_HELRO
Uncharacterized protein
Search

0.57	rap guanine nucleotide exchange factor 1

0.77	GO:0007264	small GTPase mediated signal transduction
0.66	GO:0065009	regulation of molecular function
0.48	GO:0038180	nerve growth factor signaling pathway
0.47	GO:0061028	establishment of endothelial barrier
0.47	GO:0071320	cellular response to cAMP
0.46	GO:1901888	regulation of cell junction assembly
0.45	GO:0010976	positive regulation of neuron projection development
0.43	GO:2000178	negative regulation of neural precursor cell proliferation
0.43	GO:0048008	platelet-derived growth factor receptor signaling pathway
0.43	GO:0051898	negative regulation of protein kinase B signaling

0.75	GO:0005085	guanyl-nucleotide exchange factor activity
0.43	GO:0017016	Ras GTPase binding
0.34	GO:0017124	SH3 domain binding

0.45	GO:0005622	intracellular
0.42	GO:0031982	vesicle
0.41	GO:0012505	endomembrane system
0.33	GO:0098805	whole membrane
0.33	GO:0098588	bounding membrane of organelle
0.32	GO:0043234	protein complex

tr|T1G3I7|T1G3I7_HELRO
Uncharacterized protein
Search

tr|T1G3I8|T1G3I8_HELRO
Protein Wnt
Search

0.77	GO:0016055	Wnt signaling pathway
0.70	GO:0007275	multicellular organism development
0.56	GO:0090403	oxidative stress-induced premature senescence
0.55	GO:0043616	keratinocyte proliferation
0.55	GO:0030154	cell differentiation
0.55	GO:0090399	replicative senescence
0.54	GO:0060429	epithelium development
0.54	GO:0046849	bone remodeling
0.53	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling
0.53	GO:0046330	positive regulation of JNK cascade

0.73	GO:0005102	receptor binding
0.48	GO:0039706	co-receptor binding
0.45	GO:0030545	receptor regulator activity
0.35	GO:1990782	protein tyrosine kinase binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.75	GO:0005578	proteinaceous extracellular matrix
0.52	GO:0005615	extracellular space
0.38	GO:0005737	cytoplasm
0.34	GO:1990851	Wnt-Frizzled-LRP5/6 complex
0.30	GO:0016021	integral component of membrane

tr|T1G3I9|T1G3I9_HELRO
Uncharacterized protein
Search

tr|T1G3J0|T1G3J0_HELRO
Uncharacterized protein
Search

tr|T1G3J1|T1G3J1_HELRO
Uncharacterized protein
Search

0.53	GO:0055085	transmembrane transport
0.46	GO:0045900	negative regulation of translational elongation
0.39	GO:0006869	lipid transport
0.35	GO:0002244	hematopoietic progenitor cell differentiation
0.34	GO:0060079	excitatory postsynaptic potential
0.34	GO:0035235	ionotropic glutamate receptor signaling pathway
0.33	GO:0006915	apoptotic process
0.32	GO:0006811	ion transport

0.64	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005234	extracellularly glutamate-gated ion channel activity
0.34	GO:0004970	ionotropic glutamate receptor activity
0.31	GO:0003677	DNA binding

0.35	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0098794	postsynapse
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1G3J2|T1G3J2_HELRO
Uncharacterized protein
Search

0.84	GO:1902751	positive regulation of cell cycle G2/M phase transition
0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.48	GO:0009794	regulation of mitotic cell cycle, embryonic
0.45	GO:0010256	endomembrane system organization
0.45	GO:0060305	regulation of cell diameter
0.44	GO:0007488	histoblast morphogenesis
0.44	GO:0045792	negative regulation of cell size
0.43	GO:0040019	positive regulation of embryonic development
0.43	GO:0000086	G2/M transition of mitotic cell cycle
0.43	GO:0007099	centriole replication

0.75	GO:0004725	protein tyrosine phosphatase activity
0.39	GO:0004792	thiosulfate sulfurtransferase activity
0.34	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.33	GO:0008484	sulfuric ester hydrolase activity
0.33	GO:0005515	protein binding
0.32	GO:0003676	nucleic acid binding

0.45	GO:0005622	intracellular
0.39	GO:0043228	non-membrane-bounded organelle
0.38	GO:0043227	membrane-bounded organelle
0.36	GO:0044422	organelle part
0.34	GO:0048475	coated membrane
0.33	GO:0098796	membrane protein complex
0.30	GO:0031224	intrinsic component of membrane

0.75	EC:3.1.3.48	GO:0004725
0.39	KEGG:R01931	GO:0004792

tr|T1G3J3|T1G3J3_HELRO
Uncharacterized protein
Search

100281714

0.41	Casein kinase I delta

0.63	GO:0006468	protein phosphorylation
0.44	GO:0018209	peptidyl-serine modification
0.41	GO:0016055	Wnt signaling pathway
0.41	GO:0006897	endocytosis
0.41	GO:0008360	regulation of cell shape
0.36	GO:0030999	linear element assembly
0.36	GO:0010845	positive regulation of reciprocal meiotic recombination
0.35	GO:0006282	regulation of DNA repair
0.34	GO:0018212	peptidyl-tyrosine modification
0.33	GO:0051598	meiotic recombination checkpoint

0.64	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0004713	protein tyrosine kinase activity
0.32	GO:0004185	serine-type carboxypeptidase activity
0.32	GO:0004871	signal transducer activity

0.39	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.64

GO:0004674

tr|T1G3J4|T1G3J4_HELRO
Uncharacterized protein
Search

GPSM2

0.46	G-protein-signaling modulator 2

0.68	GO:0050790	regulation of catalytic activity
0.34	GO:0006493	protein O-linked glycosylation

0.76	GO:0030695	GTPase regulator activity
0.38	GO:0042802	identical protein binding
0.33	GO:0016757	transferase activity, transferring glycosyl groups

0.30

GO:0031224

intrinsic component of membrane

0.33

GO:0016757

tr|T1G3J5|T1G3J5_HELRO
Uncharacterized protein
Search

tr|T1G3J6|T1G3J6_HELRO
Uncharacterized protein
Search

0.44	sodium-dependent multivitamin transporter

0.55	GO:0055085	transmembrane transport
0.37	GO:0006814	sodium ion transport
0.36	GO:0015705	iodide transport
0.36	GO:0006590	thyroid hormone generation
0.35	GO:0015718	monocarboxylic acid transport
0.34	GO:0051182	coenzyme transport
0.34	GO:0072337	modified amino acid transport
0.33	GO:0006768	biotin metabolic process
0.33	GO:0051180	vitamin transport
0.33	GO:0015939	pantothenate metabolic process

0.57

GO:0022857

transmembrane transporter activity

0.34	GO:0031526	brush border membrane
0.33	GO:0012506	vesicle membrane
0.33	GO:0005887	integral component of plasma membrane

tr|T1G3J7|T1G3J7_HELRO
Uncharacterized protein
Search

0.64	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.51	GO:0030522	intracellular receptor signaling pathway
0.46	GO:0042738	exogenous drug catabolic process
0.44	GO:0046618	drug export
0.43	GO:0042908	xenobiotic transport
0.43	GO:0051254	positive regulation of RNA metabolic process

0.65	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.60	GO:0003707	steroid hormone receptor activity
0.44	GO:0001012	RNA polymerase II regulatory region DNA binding
0.42	GO:0003690	double-stranded DNA binding
0.37	GO:0008144	drug binding
0.35	GO:0046965	retinoid X receptor binding
0.34	GO:0034191	apolipoprotein A-I receptor binding
0.34	GO:0051117	ATPase binding

0.61	GO:0005634	nucleus
0.43	GO:0045111	intermediate filament cytoskeleton
0.41	GO:0070013	intracellular organelle lumen
0.38	GO:0044446	intracellular organelle part
0.34	GO:0005667	transcription factor complex
0.34	GO:0005829	cytosol
0.33	GO:0043235	receptor complex
0.30	GO:0016020	membrane

0.33

EC:1.97.1

GO:0051353

tr|T1G3J8|T1G3J8_HELRO
Uncharacterized protein
Search

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.59	GO:0007399	nervous system development
0.43	GO:0007267	cell-cell signaling
0.35	GO:0001955	blood vessel maturation
0.34	GO:0048839	inner ear development
0.34	GO:0007605	sensory perception of sound
0.34	GO:0007626	locomotory behavior
0.34	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.34	GO:0010951	negative regulation of endopeptidase activity
0.34	GO:0120036	plasma membrane bounded cell projection organization

0.70	GO:0005509	calcium ion binding
0.34	GO:0004867	serine-type endopeptidase inhibitor activity
0.34	GO:0004022	alcohol dehydrogenase (NAD) activity
0.34	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.35	GO:0043005	neuron projection
0.34	GO:0032421	stereocilium bundle
0.34	GO:0098858	actin-based cell projection
0.33	GO:0030427	site of polarized growth
0.33	GO:0120038	plasma membrane bounded cell projection part
0.33	GO:0005615	extracellular space
0.32	GO:0044422	organelle part
0.32	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.34

EC:1.1.1.1

GO:0004022

tr|T1G3J9|T1G3J9_HELRO
Uncharacterized protein
Search

tr|T1G3K0|T1G3K0_HELRO
Uncharacterized protein
Search

WDR63

0.84	WD repeat-containing protein 63

0.74

GO:0007018

microtubule-based movement

0.86	GO:0045504	dynein heavy chain binding
0.85	GO:0045503	dynein light chain binding
0.85	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed

0.79

GO:0030286

dynein complex

0.85

EC:3.6.4.4

GO:0008574

tr|T1G3K1|T1G3K1_HELRO
Histone H3
Search

0.70	Histone H3, embryonic

0.40	GO:0006334	nucleosome assembly
0.33	GO:0006352	DNA-templated transcription, initiation

0.74	GO:0046982	protein heterodimerization activity
0.54	GO:0003677	DNA binding
0.39	GO:0031491	nucleosome binding

0.74	GO:0000786	nucleosome
0.60	GO:0005634	nucleus

tr|T1G3K2|T1G3K2_HELRO
Uncharacterized protein
Search

0.11	Helicase (Fragment)

0.74	GO:0000723	telomere maintenance
0.67	GO:0032392	DNA geometric change
0.62	GO:0006310	DNA recombination
0.62	GO:0006281	DNA repair
0.33	GO:0006508	proteolysis

0.67	GO:0003678	DNA helicase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0046983	protein dimerization activity
0.33	GO:0008234	cysteine-type peptidase activity
0.32	GO:0003676	nucleic acid binding

0.30

GO:0031224

intrinsic component of membrane

0.33

GO:0008234

tr|T1G3K3|T1G3K3_HELRO
Uncharacterized protein
Search

0.83	Williams-Beuren syndrome chromosomal region 16 protein homolog

0.39	GO:0002098	tRNA wobble uridine modification
0.37	GO:0000278	mitotic cell cycle
0.36	GO:0065009	regulation of molecular function
0.36	GO:0006915	apoptotic process
0.34	GO:0055114	oxidation-reduction process
0.33	GO:0016567	protein ubiquitination

0.47	GO:0016874	ligase activity
0.40	GO:0005087	Ran guanyl-nucleotide exchange factor activity
0.39	GO:0016175	superoxide-generating NADPH oxidase activity
0.37	GO:0035091	phosphatidylinositol binding
0.37	GO:0046982	protein heterodimerization activity
0.35	GO:0003723	RNA binding
0.33	GO:0004842	ubiquitin-protein transferase activity

0.51	GO:0005739	mitochondrion
0.40	GO:0033588	Elongator holoenzyme complex
0.37	GO:0000775	chromosome, centromeric region
0.36	GO:0000313	organellar ribosome
0.35	GO:0005634	nucleus
0.35	GO:0015935	small ribosomal subunit
0.34	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

0.47	EC:6	GO:0016874
0.33	KEGG:R03876	GO:0004842

tr|T1G3K4|T1G3K4_HELRO
Uncharacterized protein
Search

0.74	GO:0007219	Notch signaling pathway
0.65	GO:0007275	multicellular organism development
0.42	GO:0030154	cell differentiation
0.40	GO:0050793	regulation of developmental process
0.39	GO:0061387	regulation of extent of cell growth
0.38	GO:0030307	positive regulation of cell growth
0.38	GO:0031346	positive regulation of cell projection organization
0.38	GO:0120035	regulation of plasma membrane bounded cell projection organization
0.38	GO:0009653	anatomical structure morphogenesis
0.37	GO:0051240	positive regulation of multicellular organismal process

0.70	GO:0005509	calcium ion binding
0.49	GO:0005112	Notch binding
0.36	GO:0004872	receptor activity
0.35	GO:0071813	lipoprotein particle binding
0.34	GO:0030414	peptidase inhibitor activity
0.33	GO:0003677	DNA binding

0.38	GO:0005576	extracellular region
0.34	GO:0005886	plasma membrane
0.34	GO:0005913	cell-cell adherens junction
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

tr|T1G3K5|T1G3K5_HELRO
Reticulon-like protein
Search

tr|T1G3K6|T1G3K6_HELRO
Histone H3
Search

tr|T1G3K7|T1G3K7_HELRO
UDP-glucuronosyltransferase
Search

0.32	UDP-glucuronosyltransferase

0.38	GO:0016999	antibiotic metabolic process
0.32	GO:0007165	signal transduction
0.32	GO:0007017	microtubule-based process
0.32	GO:0007010	cytoskeleton organization
0.32	GO:0006820	anion transport
0.32	GO:0055085	transmembrane transport
0.32	GO:0006508	proteolysis
0.31	GO:0055114	oxidation-reduction process
0.31	GO:0009058	biosynthetic process

0.73	GO:0015020	glucuronosyltransferase activity
0.33	GO:0005200	structural constituent of cytoskeleton
0.32	GO:0004222	metalloendopeptidase activity
0.32	GO:0031177	phosphopantetheine binding
0.32	GO:0003924	GTPase activity
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0019001	guanyl nucleotide binding
0.32	GO:0008270	zinc ion binding
0.32	GO:0022857	transmembrane transporter activity
0.32	GO:0032555	purine ribonucleotide binding

0.42	GO:0043231	intracellular membrane-bounded organelle
0.32	GO:0005874	microtubule
0.31	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.73

EC:2.4.1.17

GO:0015020

tr|T1G3K8|T1G3K8_HELRO
Uncharacterized protein
Search

0.39

Chaperone

0.60	GO:0034975	protein folding in endoplasmic reticulum
0.53	GO:0045454	cell redox homeostasis
0.49	GO:0030433	ubiquitin-dependent ERAD pathway
0.47	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
0.44	GO:0032781	positive regulation of ATPase activity
0.43	GO:0001933	negative regulation of protein phosphorylation
0.43	GO:0009408	response to heat
0.42	GO:0055114	oxidation-reduction process
0.37	GO:0006260	DNA replication
0.36	GO:0065002	intracellular protein transmembrane transport

0.52	GO:0015036	disulfide oxidoreductase activity
0.50	GO:0051082	unfolded protein binding
0.50	GO:0031072	heat shock protein binding
0.47	GO:0051787	misfolded protein binding
0.47	GO:0051117	ATPase binding
0.46	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
0.44	GO:0001671	ATPase activator activity
0.44	GO:0051087	chaperone binding
0.38	GO:0008270	zinc ion binding
0.38	GO:0032559	adenyl ribonucleotide binding

0.52	GO:0005783	endoplasmic reticulum
0.44	GO:0043233	organelle lumen
0.40	GO:0044446	intracellular organelle part
0.39	GO:0043234	protein complex
0.35	GO:0005829	cytosol
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.46

EC:1.8.4

GO:0016671

tr|T1G3K9|T1G3K9_HELRO
Uncharacterized protein
Search

0.51

GO:0006508

proteolysis

0.59

GO:0008234

cysteine-type peptidase activity

0.30

GO:0044425

membrane part

0.59

GO:0008234

tr|T1G3L0|T1G3L0_HELRO
Uncharacterized protein
Search

0.41	Zinc finger MYM-type protein (Fragment)

0.38	GO:0006357	regulation of transcription by RNA polymerase II
0.34	GO:0007275	multicellular organism development
0.33	GO:0016310	phosphorylation
0.33	GO:0006313	transposition, DNA-mediated
0.33	GO:0015074	DNA integration

0.68	GO:0046983	protein dimerization activity
0.39	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.36	GO:0003677	DNA binding
0.34	GO:0016301	kinase activity
0.33	GO:0008270	zinc ion binding

0.38	GO:0005654	nucleoplasm
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|T1G3L1|T1G3L1_HELRO
Uncharacterized protein
Search

METTL3

0.91	Spalt like transcription factor 2

0.79	GO:0080009	mRNA methylation
0.58	GO:1990729	primary miRNA modification
0.56	GO:1903679	positive regulation of cap-independent translational initiation
0.52	GO:0034644	cellular response to UV
0.50	GO:0000398	mRNA splicing, via spliceosome
0.46	GO:0098508	endothelial to hematopoietic transition
0.45	GO:1902036	regulation of hematopoietic stem cell differentiation
0.45	GO:0045746	negative regulation of Notch signaling pathway
0.44	GO:0006974	cellular response to DNA damage stimulus
0.40	GO:0042981	regulation of apoptotic process

0.86	GO:0016422	mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity
0.49	GO:1904047	S-adenosyl-L-methionine binding
0.48	GO:0003729	mRNA binding
0.48	GO:0046982	protein heterodimerization activity
0.35	GO:0001734	mRNA (N6-adenosine)-methyltransferase activity
0.34	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.33	GO:0020037	heme binding
0.33	GO:0005506	iron ion binding
0.33	GO:0004497	monooxygenase activity
0.32	GO:0016787	hydrolase activity

0.61	GO:0005634	nucleus
0.56	GO:0036396	RNA N6-methyladenosine methyltransferase complex
0.46	GO:0031974	membrane-enclosed lumen
0.42	GO:0044446	intracellular organelle part
0.33	GO:0005737	cytoplasm

0.86

EC:2.1.1.62

GO:0016422

tr|T1G3L2|T1G3L2_HELRO
Uncharacterized protein
Search

TOP1

0.42	Mitochondrial DNA topoisomerase I

0.72	GO:0006265	DNA topological change
0.51	GO:0006338	chromatin remodeling
0.50	GO:0040016	embryonic cleavage
0.50	GO:0032922	circadian regulation of gene expression
0.47	GO:0018105	peptidyl-serine phosphorylation
0.45	GO:0006260	DNA replication
0.44	GO:0007059	chromosome segregation
0.43	GO:0042493	response to drug
0.35	GO:0071373	cellular response to luteinizing hormone stimulus
0.34	GO:0031100	animal organ regeneration

0.77	GO:0003917	DNA topoisomerase type I activity
0.55	GO:0003677	DNA binding
0.46	GO:0003682	chromatin binding
0.46	GO:0001067	regulatory region nucleic acid binding
0.46	GO:0019904	protein domain specific binding
0.44	GO:0004674	protein serine/threonine kinase activity
0.38	GO:0032559	adenyl ribonucleotide binding
0.38	GO:0008144	drug binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity

0.68	GO:0005694	chromosome
0.50	GO:0009330	DNA topoisomerase complex (ATP-hydrolyzing)
0.49	GO:0005730	nucleolus
0.48	GO:0043204	perikaryon
0.47	GO:0000932	P-body
0.44	GO:0032993	protein-DNA complex
0.44	GO:0005654	nucleoplasm
0.43	GO:0042645	mitochondrial nucleoid
0.34	GO:0000221	vacuolar proton-transporting V-type ATPase, V1 domain
0.33	GO:0019013	viral nucleocapsid

0.77

EC:5.99.1.2

GO:0003917

tr|T1G3L4|T1G3L4_HELRO
Uncharacterized protein
Search

tr|T1G3L5|T1G3L5_HELRO
Uncharacterized protein
Search

UHRF1

0.93	Ubiquitin like with PHD and ring finger domains 1

0.70	GO:0010216	maintenance of DNA methylation
0.65	GO:0010390	histone monoubiquitination
0.64	GO:0051865	protein autoubiquitination
0.59	GO:0000122	negative regulation of transcription by RNA polymerase II
0.55	GO:0090308	regulation of methylation-dependent chromatin silencing
0.38	GO:0071158	positive regulation of cell cycle arrest
0.37	GO:0008283	cell proliferation
0.36	GO:0030154	cell differentiation

0.68	GO:0044729	hemi-methylated DNA-binding
0.65	GO:0031493	nucleosomal histone binding
0.62	GO:0035064	methylated histone binding
0.61	GO:0061630	ubiquitin protein ligase activity
0.56	GO:0042802	identical protein binding
0.53	GO:0046872	metal ion binding

0.65	GO:0005720	nuclear heterochromatin
0.63	GO:0016363	nuclear matrix
0.56	GO:0005657	replication fork
0.36	GO:0005654	nucleoplasm

tr|T1G3L6|T1G3L6_HELRO
Uncharacterized protein
Search

0.44	GO:0006334	nucleosome assembly
0.35	GO:0000280	nuclear division
0.35	GO:0006352	DNA-templated transcription, initiation
0.35	GO:0048232	male gamete generation
0.35	GO:0022402	cell cycle process
0.34	GO:0022412	cellular process involved in reproduction in multicellular organism
0.34	GO:0051321	meiotic cell cycle
0.34	GO:0051382	kinetochore assembly
0.33	GO:0006004	fucose metabolic process
0.33	GO:0000278	mitotic cell cycle

0.74	GO:0046982	protein heterodimerization activity
0.55	GO:0003677	DNA binding
0.43	GO:0031491	nucleosome binding
0.34	GO:0098770	FBXO family protein binding
0.33	GO:0031418	L-ascorbic acid binding
0.33	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.33	GO:0016757	transferase activity, transferring glycosyl groups
0.32	GO:0005506	iron ion binding

0.75	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.37	GO:0005700	polytene chromosome
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0043234	protein complex
0.33	GO:0000775	chromosome, centromeric region
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0016705

tr|T1G3L7|T1G3L7_HELRO
Uncharacterized protein
Search

0.92	glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1-B-like isoform X1

0.85

GO:0016266

O-glycan processing

0.85

GO:0016263

glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity

0.30

GO:0031224

intrinsic component of membrane

0.85

EC:2.4.1.122

GO:0016263

tr|T1G3L8|T1G3L8_HELRO
Histone H3
Search

tr|T1G3M0|T1G3M0_HELRO
Histone H2B
Search

tr|T1G3M1|T1G3M1_HELRO
Histone H2B
Search

tr|T1G3M2|T1G3M2_HELRO
Uncharacterized protein
Search

0.81	GO:0006368	transcription elongation from RNA polymerase II promoter
0.74	GO:0016570	histone modification
0.55	GO:0031442	positive regulation of mRNA 3'-end processing
0.52	GO:0045638	negative regulation of myeloid cell differentiation
0.52	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter
0.51	GO:0001711	endodermal cell fate commitment
0.51	GO:0019827	stem cell population maintenance
0.51	GO:0006513	protein monoubiquitination
0.50	GO:0006378	mRNA polyadenylation
0.46	GO:0050936	xanthophore differentiation

0.48	GO:1990269	RNA polymerase II C-terminal domain phosphoserine binding
0.34	GO:0005523	tropomyosin binding
0.34	GO:0016768	spermine synthase activity
0.33	GO:0046982	protein heterodimerization activity
0.32	GO:0003677	DNA binding

0.82	GO:0016593	Cdc73/Paf1 complex
0.51	GO:0001650	fibrillar center
0.49	GO:0005813	centrosome
0.33	GO:0000786	nucleosome
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:2.5.1.22

GO:0016768

tr|T1G3M3|T1G3M3_HELRO
mRNA-capping enzyme
Search

RNGTT

0.86	mRNA-capping enzyme

0.83	GO:0098507	polynucleotide 5' dephosphorylation
0.75	GO:0006370	7-methylguanosine mRNA capping
0.73	GO:0035335	peptidyl-tyrosine dephosphorylation
0.34	GO:0007018	microtubule-based movement
0.34	GO:1903963	arachidonate transport
0.34	GO:0032309	icosanoid secretion
0.34	GO:0006366	transcription by RNA polymerase II
0.34	GO:0010628	positive regulation of gene expression
0.33	GO:0006644	phospholipid metabolic process
0.33	GO:0016032	viral process

0.84	GO:0004484	mRNA guanylyltransferase activity
0.84	GO:0004651	polynucleotide 5'-phosphatase activity
0.77	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.74	GO:0004725	protein tyrosine phosphatase activity
0.62	GO:0032550	purine ribonucleoside binding
0.62	GO:0019001	guanyl nucleotide binding
0.52	GO:0050355	triphosphatase activity
0.51	GO:0032553	ribonucleotide binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0003777	microtubule motor activity

0.60	GO:0005634	nucleus
0.34	GO:0016459	myosin complex
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0005576	extracellular region

0.84	EC:2.7.7.50	GO:0004484
0.52	KEGG:R00138	GO:0050355

tr|T1G3M5|T1G3M5_HELRO
Uncharacterized protein
Search

0.75	7-dehydrocholesterol reductase

0.55	GO:0016132	brassinosteroid biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.42	GO:0016126	sterol biosynthetic process
0.34	GO:0008203	cholesterol metabolic process
0.34	GO:0006182	cGMP biosynthetic process
0.34	GO:1902653	secondary alcohol biosynthetic process

0.73	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
0.57	GO:0009918	sterol delta7 reductase activity
0.34	GO:0004383	guanylate cyclase activity
0.33	GO:0020037	heme binding
0.33	GO:0005515	protein binding

0.46	GO:0005794	Golgi apparatus
0.40	GO:0030176	integral component of endoplasmic reticulum membrane
0.40	GO:0005886	plasma membrane

0.73

EC:1.3.1

GO:0016628

tr|T1G3M6|T1G3M6_HELRO
Uncharacterized protein
Search

PSMD4

0.72	LOW QUALITY PROTEIN: 26S proteasome non-ATPase regulatory subunit 4

0.59	GO:0006511	ubiquitin-dependent protein catabolic process
0.42	GO:0043248	proteasome assembly
0.41	GO:0010498	proteasomal protein catabolic process
0.36	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.35	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation
0.35	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia

0.43	GO:0031593	polyubiquitin modification-dependent protein binding
0.36	GO:0042802	identical protein binding
0.35	GO:0008134	transcription factor binding
0.34	GO:0003723	RNA binding

0.70	GO:1905369	endopeptidase complex
0.58	GO:0043234	protein complex
0.45	GO:0005654	nucleoplasm
0.44	GO:0005829	cytosol

tr|T1G3M7|T1G3M7_HELRO
Uncharacterized protein
Search

SH3GLB1

0.64	Endophilin-B

0.46	GO:1900739	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
0.45	GO:1903778	protein localization to vacuolar membrane
0.45	GO:1901030	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
0.45	GO:0048102	autophagic cell death
0.45	GO:2000786	positive regulation of autophagosome assembly
0.45	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity
0.44	GO:1903749	positive regulation of establishment of protein localization to mitochondrion
0.43	GO:0051084	'de novo' posttranslational protein folding
0.43	GO:0006654	phosphatidic acid biosynthetic process
0.42	GO:1905477	positive regulation of protein localization to membrane

0.44	GO:0005504	fatty acid binding
0.43	GO:0042171	lysophosphatidic acid acyltransferase activity
0.39	GO:0061778	intracellular chloride channel activity
0.38	GO:0045296	cadherin binding
0.37	GO:0042803	protein homodimerization activity
0.37	GO:0022839	ion gated channel activity
0.37	GO:0008381	mechanosensitive ion channel activity

0.49	GO:0005737	cytoplasm
0.40	GO:0031968	organelle outer membrane
0.38	GO:0031984	organelle subcompartment
0.38	GO:0030496	midbody
0.38	GO:0012505	endomembrane system
0.38	GO:0070062	extracellular exosome
0.38	GO:0043231	intracellular membrane-bounded organelle
0.37	GO:0043234	protein complex
0.37	GO:0097708	intracellular vesicle

tr|T1G3M8|T1G3M8_HELRO
Uncharacterized protein
Search

tr|T1G3N0|T1G3N0_HELRO
Uncharacterized protein
Search

0.78	GO:0098507	polynucleotide 5' dephosphorylation
0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.69	GO:0006370	7-methylguanosine mRNA capping
0.45	GO:0006266	DNA ligation
0.43	GO:0045880	positive regulation of smoothened signaling pathway
0.41	GO:0006310	DNA recombination
0.41	GO:0006281	DNA repair
0.34	GO:1903963	arachidonate transport
0.34	GO:0032309	icosanoid secretion
0.33	GO:0006644	phospholipid metabolic process

0.78	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.78	GO:0004651	polynucleotide 5'-phosphatase activity
0.77	GO:0004484	mRNA guanylyltransferase activity
0.75	GO:0004725	protein tyrosine phosphatase activity
0.52	GO:0032550	purine ribonucleoside binding
0.52	GO:0019001	guanyl nucleotide binding
0.47	GO:0032553	ribonucleotide binding
0.46	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0003910	DNA ligase (ATP) activity
0.38	GO:0030554	adenyl nucleotide binding

0.57	GO:0005634	nucleus
0.36	GO:0055044	symplast
0.35	GO:0005911	cell-cell junction
0.35	GO:0005737	cytoplasm
0.33	GO:0005576	extracellular region
0.33	GO:0043233	organelle lumen
0.32	GO:0044446	intracellular organelle part
0.32	GO:0043232	intracellular non-membrane-bounded organelle
0.32	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.78

GO:0008138

tr|T1G3N1|T1G3N1_HELRO
Uncharacterized protein
Search

tr|T1G3N2|T1G3N2_HELRO
Uncharacterized protein
Search

RTEL1

0.87	Regulator of telomere elongation helicase

0.79	GO:0010569	regulation of double-strand break repair via homologous recombination
0.74	GO:0000723	telomere maintenance
0.69	GO:0032392	DNA geometric change
0.63	GO:0006260	DNA replication
0.62	GO:0006310	DNA recombination
0.62	GO:0006281	DNA repair
0.53	GO:1904535	positive regulation of telomeric loop disassembly
0.53	GO:1904430	negative regulation of t-circle formation
0.52	GO:1904506	negative regulation of telomere maintenance in response to DNA damage
0.48	GO:0045910	negative regulation of DNA recombination

0.71	GO:0004003	ATP-dependent DNA helicase activity
0.62	GO:0051539	4 iron, 4 sulfur cluster binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0003677	DNA binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0046872	metal ion binding
0.50	GO:0070182	DNA polymerase binding

0.60	GO:0005634	nucleus
0.47	GO:0000781	chromosome, telomeric region
0.33	GO:0043233	organelle lumen
0.33	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

tr|T1G3N3|T1G3N3_HELRO
Uncharacterized protein
Search

tr|T1G3N4|T1G3N4_HELRO
Uncharacterized protein
Search

0.34

GO:0016310

phosphorylation

0.68	GO:0046983	protein dimerization activity
0.35	GO:0016301	kinase activity
0.34	GO:0008270	zinc ion binding

0.30

GO:0044425

membrane part

tr|T1G3N5|T1G3N5_HELRO
Uncharacterized protein
Search

0.52	GO:0030238	male sex determination
0.49	GO:0007548	sex differentiation
0.46	GO:0030154	cell differentiation
0.41	GO:2001141	regulation of RNA biosynthetic process
0.41	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.41	GO:0010468	regulation of gene expression
0.41	GO:0006351	transcription, DNA-templated
0.36	GO:0007166	cell surface receptor signaling pathway
0.36	GO:0198738	cell-cell signaling by wnt
0.35	GO:0060767	epithelial cell proliferation involved in prostate gland development

0.55	GO:0003677	DNA binding
0.48	GO:0005516	calmodulin binding
0.43	GO:0003700	DNA binding transcription factor activity
0.35	GO:0097157	pre-mRNA intronic binding
0.35	GO:0034236	protein kinase A catalytic subunit binding
0.35	GO:0008013	beta-catenin binding
0.34	GO:0004602	glutathione peroxidase activity
0.34	GO:0003682	chromatin binding
0.34	GO:0001067	regulatory region nucleic acid binding
0.34	GO:0046982	protein heterodimerization activity

0.61	GO:0005634	nucleus
0.44	GO:0070013	intracellular organelle lumen
0.40	GO:0044446	intracellular organelle part
0.34	GO:0005667	transcription factor complex
0.33	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.34

EC:1.11.1.9

GO:0004602

tr|T1G3N6|T1G3N6_HELRO
Histone H3
Search

0.42	GO:0006334	nucleosome assembly
0.35	GO:0006352	DNA-templated transcription, initiation

0.74	GO:0046982	protein heterodimerization activity
0.55	GO:0003677	DNA binding
0.37	GO:0031491	nucleosome binding

0.75	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.34	GO:0005700	polytene chromosome
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0043234	protein complex

tr|T1G3N7|T1G3N7_HELRO
Uncharacterized protein
Search

0.77	GO:0048514	blood vessel morphogenesis
0.69	GO:0043066	negative regulation of apoptotic process
0.68	GO:0051005	negative regulation of lipoprotein lipase activity
0.67	GO:0048646	anatomical structure formation involved in morphogenesis
0.65	GO:0070328	triglyceride homeostasis
0.58	GO:0010519	negative regulation of phospholipase activity
0.57	GO:0055091	phospholipid homeostasis
0.56	GO:0050996	positive regulation of lipid catabolic process
0.55	GO:0060840	artery development
0.55	GO:0042632	cholesterol homeostasis

0.57	GO:0004857	enzyme inhibitor activity
0.54	GO:0005178	integrin binding
0.52	GO:0008083	growth factor activity
0.48	GO:0042802	identical protein binding
0.38	GO:0030674	protein binding, bridging
0.35	GO:0008201	heparin binding
0.35	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity
0.33	GO:0003723	RNA binding

0.70	GO:0005615	extracellular space
0.53	GO:0005769	early endosome
0.50	GO:0009986	cell surface
0.49	GO:0005794	Golgi apparatus
0.39	GO:0005578	proteinaceous extracellular matrix
0.35	GO:0030027	lamellipodium
0.35	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.35

GO:0016538

tr|T1G3N9|T1G3N9_HELRO
Uncharacterized protein
Search

TMEM30B

0.81	Cell cycle control protein 50B

0.48	GO:0015914	phospholipid transport
0.48	GO:0070863	positive regulation of protein exit from endoplasmic reticulum
0.40	GO:0071705	nitrogen compound transport
0.37	GO:0034204	lipid translocation
0.36	GO:0044088	regulation of vacuole organization
0.36	GO:0051301	cell division
0.35	GO:0007166	cell surface receptor signaling pathway
0.33	GO:0010570	regulation of filamentous growth
0.33	GO:0051666	actin cortical patch localization
0.33	GO:0042147	retrograde transport, endosome to Golgi

0.49	GO:0015247	aminophospholipid transmembrane transporter activity
0.37	GO:0004012	phospholipid-translocating ATPase activity
0.34	GO:0008483	transaminase activity
0.34	GO:0030170	pyridoxal phosphate binding
0.33	GO:0070569	uridylyltransferase activity
0.33	GO:0005515	protein binding
0.32	GO:0008237	metallopeptidase activity

0.37	GO:1990531	Lem3p-Dnf1p complex
0.36	GO:0005783	endoplasmic reticulum
0.35	GO:0005770	late endosome
0.34	GO:0005886	plasma membrane
0.33	GO:1990530	Cdc50p-Drs2p complex
0.33	GO:0031984	organelle subcompartment
0.33	GO:0010008	endosome membrane
0.32	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.32	GO:0044431	Golgi apparatus part
0.32	GO:0005829	cytosol

0.37

EC:3.6.3.1

GO:0004012

tr|T1G3P0|T1G3P0_HELRO
Uncharacterized protein
Search

0.40	GO:0006898	receptor-mediated endocytosis
0.39	GO:0007275	multicellular organism development
0.38	GO:0030509	BMP signaling pathway
0.38	GO:0060828	regulation of canonical Wnt signaling pathway
0.36	GO:0030154	cell differentiation
0.36	GO:1901342	regulation of vasculature development
0.36	GO:0006030	chitin metabolic process
0.35	GO:0070858	negative regulation of bile acid biosynthetic process
0.35	GO:0042632	cholesterol homeostasis
0.34	GO:0007186	G-protein coupled receptor signaling pathway

0.66	GO:0005509	calcium ion binding
0.39	GO:0004872	receptor activity
0.36	GO:0008061	chitin binding
0.34	GO:0004252	serine-type endopeptidase activity
0.34	GO:0004871	signal transducer activity
0.33	GO:0071814	protein-lipid complex binding
0.33	GO:0003779	actin binding
0.33	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.32	GO:0003735	structural constituent of ribosome

0.35	GO:0005794	Golgi apparatus
0.35	GO:0005576	extracellular region
0.33	GO:0010008	endosome membrane
0.33	GO:0005829	cytosol
0.32	GO:0005887	integral component of plasma membrane
0.32	GO:0005840	ribosome

0.34

GO:0004252

tr|T1G3P1|T1G3P1_HELRO
Peptidyl-prolyl cis-trans isomerase
Search

0.47	Peptidyl-prolyl cis-trans isomerase

0.72	GO:0000413	protein peptidyl-prolyl isomerization
0.69	GO:0006457	protein folding
0.40	GO:0045836	positive regulation of meiotic nuclear division
0.39	GO:0030437	ascospore formation
0.38	GO:0016575	histone deacetylation
0.36	GO:0001666	response to hypoxia
0.35	GO:0006915	apoptotic process
0.35	GO:0010275	NAD(P)H dehydrogenase complex assembly
0.33	GO:0046907	intracellular transport

0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.40	GO:0016018	cyclosporin A binding
0.35	GO:0043424	protein histidine kinase binding
0.33	GO:0008270	zinc ion binding
0.32	GO:0003723	RNA binding

0.40	GO:0034967	Set3 complex
0.38	GO:0005758	mitochondrial intermembrane space
0.35	GO:0030445	yeast-form cell wall
0.35	GO:0097311	biofilm matrix
0.35	GO:0009533	chloroplast stromal thylakoid
0.34	GO:0031977	thylakoid lumen
0.33	GO:0009535	chloroplast thylakoid membrane

0.72

EC:5.2.1.8

GO:0003755

tr|T1G3P2|T1G3P2_HELRO
Uncharacterized protein
Search

tr|T1G3P3|T1G3P3_HELRO
Uncharacterized protein
Search

0.57	GO:0045995	regulation of embryonic development
0.55	GO:0051270	regulation of cellular component movement
0.55	GO:0040012	regulation of locomotion
0.53	GO:0030155	regulation of cell adhesion
0.52	GO:0007155	cell adhesion
0.44	GO:0007275	multicellular organism development
0.43	GO:0060668	regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling
0.43	GO:0048468	cell development
0.43	GO:0009653	anatomical structure morphogenesis
0.41	GO:0071695	anatomical structure maturation

0.52	GO:0005102	receptor binding
0.52	GO:0005509	calcium ion binding
0.48	GO:0008022	protein C-terminus binding
0.43	GO:0043237	laminin-1 binding
0.37	GO:0050839	cell adhesion molecule binding
0.36	GO:0032403	protein complex binding
0.34	GO:0005201	extracellular matrix structural constituent
0.33	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.32	GO:0008270	zinc ion binding
0.32	GO:0003676	nucleic acid binding

0.50	GO:0005576	extracellular region
0.37	GO:0005794	Golgi apparatus
0.37	GO:0044456	synapse part
0.35	GO:0043202	lysosomal lumen
0.34	GO:0098590	plasma membrane region
0.34	GO:0055120	striated muscle dense body
0.34	GO:0097458	neuron part
0.34	GO:0031982	vesicle
0.34	GO:0005925	focal adhesion
0.34	GO:0043234	protein complex

0.33

EC:3.4.19.12

GO:0036459

tr|T1G3P4|T1G3P4_HELRO
Uncharacterized protein
Search

0.48	Plasma alpha-L-fucosidase

0.79	GO:0006004	fucose metabolic process
0.44	GO:0016139	glycoside catabolic process
0.42	GO:2000535	regulation of entry of bacterium into host cell
0.39	GO:0009617	response to bacterium
0.34	GO:0019377	glycolipid catabolic process
0.34	GO:0035335	peptidyl-tyrosine dephosphorylation
0.33	GO:0033014	tetrapyrrole biosynthetic process

0.80	GO:0004560	alpha-L-fucosidase activity
0.34	GO:0004852	uroporphyrinogen-III synthase activity
0.34	GO:0004725	protein tyrosine phosphatase activity

0.38	GO:0005615	extracellular space
0.34	GO:0005764	lysosome
0.30	GO:0016020	membrane

0.80	EC:3.2.1.51	GO:0004560
0.34	KEGG:R03165	GO:0004852

tr|T1G3P5|T1G3P5_HELRO
Uncharacterized protein
Search

ESRRA

0.80	Perinereis aibuhitensis estrogen receptor mRNA

0.78	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.42	GO:0051254	positive regulation of RNA metabolic process
0.41	GO:0010557	positive regulation of macromolecule biosynthetic process
0.41	GO:0031328	positive regulation of cellular biosynthetic process
0.41	GO:0051253	negative regulation of RNA metabolic process
0.41	GO:0010558	negative regulation of macromolecule biosynthetic process

0.80	GO:0003707	steroid hormone receptor activity
0.77	GO:0005496	steroid binding
0.65	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.44	GO:0019904	protein domain specific binding
0.43	GO:0001012	RNA polymerase II regulatory region DNA binding
0.41	GO:0003690	double-stranded DNA binding
0.32	GO:0016491	oxidoreductase activity

0.61	GO:0005634	nucleus
0.47	GO:0045171	intercellular bridge
0.43	GO:0015630	microtubule cytoskeleton
0.41	GO:0043233	organelle lumen
0.39	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.32

GO:0016491

tr|T1G3P6|T1G3P6_HELRO
Uncharacterized protein
Search

tr|T1G3P7|T1G3P7_HELRO
Uncharacterized protein
Search

ADAM24

0.86	A disintegrin and metallopeptidase domain 24 (Fragment)

0.60	GO:0006508	proteolysis
0.55	GO:0007229	integrin-mediated signaling pathway
0.40	GO:0007219	Notch signaling pathway
0.40	GO:0060468	prevention of polyspermy
0.39	GO:0006281	DNA repair
0.33	GO:0018108	peptidyl-tyrosine phosphorylation

0.70	GO:0004222	metalloendopeptidase activity
0.52	GO:0046872	metal ion binding
0.42	GO:0003684	damaged DNA binding
0.34	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0016020

membrane

0.70

GO:0004222

tr|T1G3P8|T1G3P8_HELRO
Uncharacterized protein
Search

ETNK2

0.69	Ethanolamine kinase

0.56	GO:0016310	phosphorylation
0.55	GO:0035264	multicellular organism growth
0.53	GO:0006646	phosphatidylethanolamine biosynthetic process
0.52	GO:0009791	post-embryonic development
0.52	GO:0001890	placenta development
0.51	GO:0001701	in utero embryonic development
0.34	GO:0006508	proteolysis

0.59	GO:0004305	ethanolamine kinase activity
0.39	GO:0004103	choline kinase activity
0.35	GO:0070001	aspartic-type peptidase activity
0.35	GO:0004175	endopeptidase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0008270	zinc ion binding
0.33	GO:0003676	nucleic acid binding

0.34	GO:0005829	cytosol
0.34	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.59	EC:2.7.1.82	GO:0004305
0.59	KEGG:R01468	GO:0004305

tr|T1G3P9|T1G3P9_HELRO
Uncharacterized protein
Search

0.12	Zinc finger MYM-type protein 1 (Fragment)

0.68	GO:0046983	protein dimerization activity
0.38	GO:0008270	zinc ion binding

0.30

GO:0044425

membrane part

tr|T1G3Q0|T1G3Q0_HELRO
Uncharacterized protein
Search

ECHS1

0.38	Enoyl-CoA hydrataseserine-threonine

0.48	GO:0006635	fatty acid beta-oxidation
0.33	GO:0005996	monosaccharide metabolic process

0.51	GO:0004300	enoyl-CoA hydratase activity
0.35	GO:0016508	long-chain-enoyl-CoA hydratase activity
0.34	GO:0003859	3-hydroxybutyryl-CoA dehydratase activity
0.34	GO:0016853	isomerase activity
0.33	GO:0048029	monosaccharide binding

0.41	GO:0005739	mitochondrion
0.35	GO:0043233	organelle lumen
0.34	GO:0070062	extracellular exosome
0.34	GO:0044446	intracellular organelle part
0.30	GO:0044425	membrane part

0.51	EC:4.2.1.17	GO:0004300
0.34	KEGG:R03027	GO:0003859

tr|T1G3Q1|T1G3Q1_HELRO
Uncharacterized protein
Search

tr|T1G3Q2|T1G3Q2_HELRO
Uncharacterized protein
Search

tr|T1G3Q3|T1G3Q3_HELRO
Uncharacterized protein
Search

tr|T1G3Q4|T1G3Q4_HELRO
Uncharacterized protein
Search

tr|T1G3Q5|T1G3Q5_HELRO
Uncharacterized protein
Search

0.53	Serine-protein kinase ATM

0.74	GO:0090399	replicative senescence
0.71	GO:0016572	histone phosphorylation
0.69	GO:0010212	response to ionizing radiation
0.68	GO:0000077	DNA damage checkpoint
0.66	GO:0000723	telomere maintenance
0.59	GO:0002331	pre-B cell allelic exclusion
0.59	GO:1904882	regulation of telomerase catalytic core complex assembly
0.59	GO:0097694	establishment of RNA localization to telomere
0.58	GO:0006975	DNA damage induced protein phosphorylation
0.58	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage

0.61	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0047485	protein N-terminus binding
0.55	GO:0016303	1-phosphatidylinositol-3-kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0008144	drug binding
0.50	GO:0032403	protein complex binding
0.47	GO:0046983	protein dimerization activity
0.36	GO:0003735	structural constituent of ribosome

0.52	GO:0000781	chromosome, telomeric region
0.51	GO:0005819	spindle
0.50	GO:1990391	DNA repair complex
0.49	GO:0005730	nucleolus
0.36	GO:0031410	cytoplasmic vesicle
0.36	GO:0005840	ribosome
0.35	GO:0005654	nucleoplasm
0.34	GO:0044454	nuclear chromosome part
0.30	GO:0016020	membrane

0.61	EC:2.7.11	GO:0004674
0.55	KEGG:R03362	GO:0016303

tr|T1G3Q6|T1G3Q6_HELRO
Uncharacterized protein
Search

TACR3

0.60	Urechistachykinin receptor

0.85	GO:0007217	tachykinin receptor signaling pathway
0.54	GO:1902093	positive regulation of flagellated sperm motility
0.40	GO:0045987	positive regulation of smooth muscle contraction
0.40	GO:0042220	response to cocaine
0.39	GO:0070472	regulation of uterine smooth muscle contraction
0.38	GO:0007218	neuropeptide signaling pathway
0.38	GO:0043278	response to morphine
0.38	GO:0042053	regulation of dopamine metabolic process
0.38	GO:0010460	positive regulation of heart rate
0.38	GO:0045777	positive regulation of blood pressure

0.86	GO:0004995	tachykinin receptor activity
0.37	GO:0050254	rhodopsin kinase activity
0.33	GO:0005515	protein binding

0.55	GO:0005886	plasma membrane
0.53	GO:0097225	sperm midpiece
0.37	GO:0043025	neuronal cell body
0.37	GO:0030425	dendrite
0.37	GO:0031252	cell leading edge
0.35	GO:0061827	sperm head
0.34	GO:0005634	nucleus
0.33	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.37

EC:2.7.11.14

GO:0050254

tr|T1G3Q7|T1G3Q7_HELRO
Uncharacterized protein
Search

RNF170

0.91	E5 ubiquitin-protein ligase

0.39	GO:0016567	protein ubiquitination
0.34	GO:0043009	chordate embryonic development

0.52	GO:0046872	metal ion binding
0.51	GO:0016874	ligase activity
0.34	GO:0016740	transferase activity
0.33	GO:0005515	protein binding
0.31	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.39	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.51

GO:0016874

tr|T1G3Q8|T1G3Q8_HELRO
Uncharacterized protein
Search

tr|T1G3Q9|T1G3Q9_HELRO
Uncharacterized protein
Search

MRPS5

0.94	Mitochondrial ribosomal protein S5

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.35	GO:0043624	cellular protein complex disassembly
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.64	GO:0003735	structural constituent of ribosome
0.59	GO:0003723	RNA binding
0.34	GO:0003924	GTPase activity
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0019001	guanyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005840	ribosome
0.52	GO:0005759	mitochondrial matrix
0.44	GO:0044445	cytosolic part
0.35	GO:0031966	mitochondrial membrane
0.35	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1G3R0|T1G3R0_HELRO
Uncharacterized protein
Search

0.53	Testis-specific serine/threonine-protein kinase 3 (inferred by orthology to a human protein)

0.63	GO:0006468	protein phosphorylation
0.42	GO:0007165	signal transduction
0.39	GO:0030010	establishment of cell polarity
0.38	GO:0000226	microtubule cytoskeleton organization
0.35	GO:0007049	cell cycle
0.35	GO:0018209	peptidyl-serine modification
0.34	GO:0048523	negative regulation of cellular process
0.34	GO:0071988	protein localization to spindle pole body
0.34	GO:0035262	gonad morphogenesis
0.33	GO:0055085	transmembrane transport

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0005509	calcium ion binding
0.34	GO:0022857	transmembrane transporter activity
0.33	GO:0017049	GTP-Rho binding
0.33	GO:0005516	calmodulin binding

0.35	GO:0005634	nucleus
0.34	GO:0005938	cell cortex
0.33	GO:0005816	spindle pole body
0.33	GO:0005935	cellular bud neck
0.30	GO:0016020	membrane

tr|T1G3R1|T1G3R1_HELRO
Uncharacterized protein
Search

0.49	YdjC chitooligosaccharide deacetylase homolog

0.60

GO:0005975

carbohydrate metabolic process

0.35	GO:0046872	metal ion binding
0.34	GO:0016787	hydrolase activity

0.34

GO:0016787

tr|T1G3R2|T1G3R2_HELRO
Uncharacterized protein
Search

0.79	Signal recognition particle receptor subunit alpha

0.76	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0007409	axonogenesis
0.34	GO:0050708	regulation of protein secretion

0.82	GO:0005047	signal recognition particle binding
0.66	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.83	GO:0005785	signal recognition particle receptor complex
0.30	GO:0031224	intrinsic component of membrane

tr|T1G3R3|T1G3R3_HELRO
Uncharacterized protein
Search

0.77	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.44	GO:0007283	spermatogenesis
0.44	GO:1902680	positive regulation of RNA biosynthetic process
0.43	GO:1902679	negative regulation of RNA biosynthetic process
0.39	GO:0005975	carbohydrate metabolic process
0.39	GO:1900078	positive regulation of cellular response to insulin stimulus

0.79	GO:0003707	steroid hormone receptor activity
0.78	GO:0005496	steroid binding
0.65	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.46	GO:0019904	protein domain specific binding
0.45	GO:0001012	RNA polymerase II regulatory region DNA binding
0.43	GO:0003690	double-stranded DNA binding
0.32	GO:0016491	oxidoreductase activity

0.61	GO:0005634	nucleus
0.49	GO:0045171	intercellular bridge
0.44	GO:0015630	microtubule cytoskeleton
0.43	GO:0043233	organelle lumen
0.40	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.32

GO:0016491

tr|T1G3R4|T1G3R4_HELRO
Uncharacterized protein
Search

0.48	Plasma alpha-L-fucosidase

0.79	GO:0006004	fucose metabolic process
0.39	GO:0016139	glycoside catabolic process
0.37	GO:2000535	regulation of entry of bacterium into host cell
0.35	GO:0009617	response to bacterium
0.34	GO:0019377	glycolipid catabolic process
0.34	GO:0035335	peptidyl-tyrosine dephosphorylation
0.33	GO:0033014	tetrapyrrole biosynthetic process

0.80	GO:0004560	alpha-L-fucosidase activity
0.34	GO:0004852	uroporphyrinogen-III synthase activity
0.34	GO:0004725	protein tyrosine phosphatase activity

0.35	GO:0005576	extracellular region
0.34	GO:0005764	lysosome
0.30	GO:0016020	membrane

0.80	EC:3.2.1.51	GO:0004560
0.34	KEGG:R03165	GO:0004852

tr|T1G3R5|T1G3R5_HELRO
Uncharacterized protein
Search

tr|T1G3R6|T1G3R6_HELRO
Uncharacterized protein
Search

SLC35B3

0.95	Adenosine 3'-phospho 5'-phosphosulfate transporter 2

0.55	GO:0055085	transmembrane transport
0.55	GO:0046963	3'-phosphoadenosine 5'-phosphosulfate transport
0.43	GO:0015012	heparan sulfate proteoglycan biosynthetic process
0.35	GO:0050428	3'-phosphoadenosine 5'-phosphosulfate biosynthetic process
0.34	GO:0007275	multicellular organism development
0.32	GO:0006518	peptide metabolic process
0.32	GO:0043604	amide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0010467	gene expression

0.55	GO:0046964	3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity
0.33	GO:0003735	structural constituent of ribosome
0.32	GO:0003677	DNA binding

0.48	GO:0030173	integral component of Golgi membrane
0.46	GO:0005783	endoplasmic reticulum
0.44	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.43	GO:0000137	Golgi cis cisterna
0.33	GO:0005739	mitochondrion
0.33	GO:0005840	ribosome

tr|T1G3R7|T1G3R7_HELRO
Uncharacterized protein
Search

0.87	Electron transfer flavoprotein regulatory factor 1

0.65

GO:0022904

respiratory electron transport chain

0.44	GO:0003924	GTPase activity
0.43	GO:0032550	purine ribonucleoside binding
0.43	GO:0019001	guanyl nucleotide binding
0.43	GO:0005515	protein binding
0.39	GO:0032555	purine ribonucleotide binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding

0.59

GO:0005739

mitochondrion

tr|T1G3R8|T1G3R8_HELRO
Uncharacterized protein
Search

0.56	Zinc finger BED domain-containing protein (Fragment)

0.36	GO:0006357	regulation of transcription by RNA polymerase II
0.33	GO:0006468	protein phosphorylation
0.33	GO:0006508	proteolysis

0.68	GO:0046983	protein dimerization activity
0.44	GO:0003677	DNA binding
0.37	GO:0001067	regulatory region nucleic acid binding
0.35	GO:0003700	DNA binding transcription factor activity
0.34	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0017171	serine hydrolase activity
0.33	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.33	GO:0016301	kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding

0.35	GO:0005634	nucleus
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0044446	intracellular organelle part
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0016773

tr|T1G3R9|T1G3R9_HELRO
Uncharacterized protein
Search

DNM1

0.68	Dynamin 1 short form

0.67	GO:0006897	endocytosis
0.47	GO:0070142	synaptic vesicle budding
0.47	GO:0051932	synaptic transmission, GABAergic
0.47	GO:0003374	dynamin family protein polymerization involved in mitochondrial fission
0.46	GO:0007032	endosome organization
0.45	GO:0036465	synaptic vesicle recycling
0.45	GO:0000266	mitochondrial fission
0.45	GO:0008344	adult locomotory behavior
0.44	GO:0007605	sensory perception of sound
0.44	GO:1901998	toxin transport

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0019901	protein kinase binding
0.42	GO:0042802	identical protein binding
0.42	GO:0008017	microtubule binding
0.41	GO:0046983	protein dimerization activity
0.39	GO:0031749	D2 dopamine receptor binding

0.46	GO:0001917	photoreceptor inner segment
0.44	GO:0043209	myelin sheath
0.43	GO:0045202	synapse
0.42	GO:0030117	membrane coat
0.42	GO:0005654	nucleoplasm
0.42	GO:0005874	microtubule
0.39	GO:0031966	mitochondrial membrane
0.38	GO:0043196	varicosity
0.38	GO:0099503	secretory vesicle
0.36	GO:0030133	transport vesicle

tr|T1G3S0|T1G3S0_HELRO
Uncharacterized protein
Search

0.53	Non-specific protein-tyrosine kinase (Fragment)

0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.60	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.57	GO:0044344	cellular response to fibroblast growth factor stimulus
0.55	GO:0008284	positive regulation of cell proliferation
0.45	GO:0032526	response to retinoic acid
0.45	GO:0045026	plasma membrane fusion
0.44	GO:0048731	system development
0.44	GO:0016525	negative regulation of angiogenesis
0.44	GO:0030336	negative regulation of cell migration
0.43	GO:0001701	in utero embryonic development

0.77	GO:0004713	protein tyrosine kinase activity
0.61	GO:0019199	transmembrane receptor protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0051015	actin filament binding
0.37	GO:0003777	microtubule motor activity
0.37	GO:0008017	microtubule binding
0.35	GO:0005102	receptor binding
0.35	GO:0005044	scavenger receptor activity

0.38	GO:0005886	plasma membrane
0.37	GO:0016459	myosin complex
0.35	GO:0098562	cytoplasmic side of membrane
0.35	GO:0019898	extrinsic component of membrane
0.31	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.77

GO:0004713

tr|T1G3S1|T1G3S1_HELRO
Uncharacterized protein
Search

tr|T1G3S2|T1G3S2_HELRO
Uncharacterized protein
Search

ATP7B

0.80	ATPase copper transporting beta

0.68	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.65	GO:0030001	metal ion transport
0.58	GO:0051208	sequestering of calcium ion
0.54	GO:0006882	cellular zinc ion homeostasis
0.53	GO:0007595	lactation
0.53	GO:0046688	response to copper ion
0.52	GO:0006878	cellular copper ion homeostasis
0.46	GO:0046907	intracellular transport
0.44	GO:0098662	inorganic cation transmembrane transport
0.37	GO:0051353	positive regulation of oxidoreductase activity

0.70	GO:0005507	copper ion binding
0.68	GO:0019829	cation-transporting ATPase activity
0.53	GO:0005375	copper ion transmembrane transporter activity
0.52	GO:1901265	nucleoside phosphate binding
0.50	GO:0036094	small molecule binding
0.50	GO:0015662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
0.41	GO:0097367	carbohydrate derivative binding
0.41	GO:0008144	drug binding
0.40	GO:0043168	anion binding
0.38	GO:0032767	copper-dependent protein binding

0.55	GO:0032588	trans-Golgi network membrane
0.54	GO:0016323	basolateral plasma membrane
0.53	GO:0005770	late endosome
0.52	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0030140	trans-Golgi network transport vesicle
0.35	GO:0005923	bicellular tight junction
0.35	GO:0045177	apical part of cell
0.34	GO:0005783	endoplasmic reticulum
0.34	GO:0005887	integral component of plasma membrane
0.33	GO:0005739	mitochondrion

0.37

EC:1.97.1

GO:0051353

tr|T1G3S3|T1G3S3_HELRO
Uncharacterized protein
Search

tr|T1G3S4|T1G3S4_HELRO
Uncharacterized protein
Search

FUCA2

0.48	Plasma alpha-L-fucosidase

0.79	GO:0006004	fucose metabolic process
0.47	GO:0016139	glycoside catabolic process
0.41	GO:2000535	regulation of entry of bacterium into host cell
0.38	GO:0009617	response to bacterium
0.36	GO:0019377	glycolipid catabolic process
0.34	GO:0043312	neutrophil degranulation
0.34	GO:0035335	peptidyl-tyrosine dephosphorylation
0.33	GO:0006027	glycosaminoglycan catabolic process
0.33	GO:0033014	tetrapyrrole biosynthetic process

0.80	GO:0004560	alpha-L-fucosidase activity
0.34	GO:0004852	uroporphyrinogen-III synthase activity
0.34	GO:0004725	protein tyrosine phosphatase activity
0.33	GO:0030246	carbohydrate binding

0.39	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.36	GO:0005764	lysosome
0.34	GO:0034774	secretory granule lumen
0.34	GO:0005775	vacuolar lumen
0.30	GO:0016020	membrane

0.80	EC:3.2.1.51	GO:0004560
0.34	KEGG:R03165	GO:0004852

tr|T1G3S5|T1G3S5_HELRO
Uncharacterized protein
Search

tr|T1G3S6|T1G3S6_HELRO
Uncharacterized protein
Search

SLC25A26

0.91	S-adenosylmethionine mitochondrial carrier protein isoform A

0.50	GO:1901962	S-adenosyl-L-methionine transmembrane transport
0.45	GO:0006839	mitochondrial transport
0.33	GO:0006811	ion transport
0.30	GO:0008152	metabolic process

0.51	GO:0000095	S-adenosyl-L-methionine transmembrane transporter activity
0.32	GO:0016787	hydrolase activity

0.45	GO:0005739	mitochondrion
0.41	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016787

tr|T1G3S7|T1G3S7_HELRO
Uncharacterized protein
Search

CBS

0.60	Cystathionine beta-synthase

0.76	GO:0019343	cysteine biosynthetic process via cystathionine
0.75	GO:0006535	cysteine biosynthetic process from serine
0.37	GO:1901700	response to oxygen-containing compound
0.36	GO:0006979	response to oxidative stress
0.35	GO:0001958	endochondral ossification
0.35	GO:0060351	cartilage development involved in endochondral bone morphogenesis
0.35	GO:0001974	blood vessel remodeling
0.35	GO:0030823	regulation of cGMP metabolic process
0.35	GO:0033273	response to vitamin
0.35	GO:0021587	cerebellum morphogenesis

0.77	GO:0004122	cystathionine beta-synthase activity
0.39	GO:0004124	cysteine synthase activity
0.38	GO:0030170	pyridoxal phosphate binding
0.35	GO:0020037	heme binding

0.46	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.77

EC:4.2.1.22

GO:0004122

tr|T1G3S8|T1G3S8_HELRO
Uncharacterized protein
Search

TPH2

0.91	Tryptophan hydroxylase R

0.80	GO:0042427	serotonin biosynthetic process
0.65	GO:0009072	aromatic amino acid family metabolic process
0.51	GO:0055114	oxidation-reduction process
0.41	GO:0061377	mammary gland lobule development
0.41	GO:0046849	bone remodeling
0.41	GO:0045600	positive regulation of fat cell differentiation
0.38	GO:0071285	cellular response to lithium ion
0.38	GO:0007623	circadian rhythm
0.38	GO:0014823	response to activity
0.38	GO:0043627	response to estrogen

0.81	GO:0004510	tryptophan 5-monooxygenase activity
0.60	GO:0005506	iron ion binding

0.50	GO:0043005	neuron projection
0.35	GO:0005829	cytosol

0.81

EC:1.14.16.4

GO:0004510

tr|T1G3S9|T1G3S9_HELRO
Uncharacterized protein
Search

0.10	Zinc finger protein 3 (Fragment)

0.40	GO:1903506	regulation of nucleic acid-templated transcription
0.40	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.40	GO:0010468	regulation of gene expression
0.37	GO:0002244	hematopoietic progenitor cell differentiation
0.35	GO:0006351	transcription, DNA-templated
0.35	GO:1900112	regulation of histone H3-K9 trimethylation
0.33	GO:0071805	potassium ion transmembrane transport
0.33	GO:1902679	negative regulation of RNA biosynthetic process

0.51	GO:0003676	nucleic acid binding
0.41	GO:0046872	metal ion binding
0.38	GO:0003700	DNA binding transcription factor activity
0.34	GO:0003682	chromatin binding
0.34	GO:0005267	potassium channel activity

0.41	GO:0005634	nucleus
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|T1G3T0|T1G3T0_HELRO
Uncharacterized protein
Search

0.72	Homeobox protein prospero

0.40	GO:0055007	cardiac muscle cell differentiation
0.40	GO:0000122	negative regulation of transcription by RNA polymerase II
0.39	GO:0030182	neuron differentiation
0.39	GO:0045944	positive regulation of transcription by RNA polymerase II
0.36	GO:0055060	asymmetric neuroblast division resulting in ganglion mother cell formation
0.36	GO:0042673	regulation of retinal cone cell fate specification
0.36	GO:0042676	compound eye cone cell fate commitment
0.35	GO:0007402	ganglion mother cell fate determination
0.35	GO:0070314	G1 to G0 transition
0.35	GO:0045676	regulation of R7 cell differentiation

0.55	GO:0003677	DNA binding
0.41	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding

0.37	GO:0005634	nucleus
0.35	GO:0045180	basal cortex
0.35	GO:0045179	apical cortex
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1G3T1|T1G3T1_HELRO
Uncharacterized protein
Search

0.49	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.48	GO:0007528	neuromuscular junction development
0.46	GO:0071711	basement membrane organization
0.46	GO:0061304	retinal blood vessel morphogenesis
0.44	GO:0001569	branching involved in blood vessel morphogenesis
0.44	GO:0061333	renal tubule morphogenesis
0.44	GO:0071230	cellular response to amino acid stimulus
0.43	GO:0060322	head development
0.43	GO:0007399	nervous system development
0.41	GO:0010951	negative regulation of endopeptidase activity

0.67	GO:0005201	extracellular matrix structural constituent
0.45	GO:0048407	platelet-derived growth factor binding
0.45	GO:0042302	structural constituent of cuticle
0.42	GO:0004867	serine-type endopeptidase inhibitor activity
0.35	GO:0097493	structural molecule activity conferring elasticity
0.33	GO:0008061	chitin binding
0.33	GO:0005509	calcium ion binding
0.33	GO:0008932	lytic endotransglycosylase activity
0.33	GO:0030246	carbohydrate binding
0.33	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.64	GO:0005581	collagen trimer
0.60	GO:0005604	basement membrane
0.50	GO:0098645	collagen network
0.42	GO:0005615	extracellular space
0.41	GO:0031594	neuromuscular junction
0.34	GO:0042383	sarcolemma
0.34	GO:0005788	endoplasmic reticulum lumen
0.34	GO:0019867	outer membrane
0.32	GO:0005887	integral component of plasma membrane
0.32	GO:0044462	external encapsulating structure part

0.33

EC:2.4.99

GO:0008932

tr|T1G3T2|T1G3T2_HELRO
Uncharacterized protein
Search

0.71	Polycomb group RING finger protein 6 (Fragment)

0.74	GO:0036353	histone H2A-K119 monoubiquitination
0.63	GO:0045892	negative regulation of transcription, DNA-templated
0.48	GO:0006357	regulation of transcription by RNA polymerase II
0.39	GO:0006351	transcription, DNA-templated
0.38	GO:0007568	aging
0.36	GO:0070317	negative regulation of G0 to G1 transition
0.36	GO:0048589	developmental growth

0.59	GO:0008022	protein C-terminus binding
0.53	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.51	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.38	GO:0046872	metal ion binding
0.35	GO:0019904	protein domain specific binding

0.82	GO:0031519	PcG protein complex
0.70	GO:0000152	nuclear ubiquitin ligase complex
0.51	GO:0005654	nucleoplasm

tr|T1G3T3|T1G3T3_HELRO
Uncharacterized protein
Search

0.73	Inward rectifier potassium channel

0.78	GO:0034765	regulation of ion transmembrane transport
0.71	GO:0006813	potassium ion transport
0.61	GO:0098655	cation transmembrane transport
0.47	GO:0090099	negative regulation of decapentaplegic signaling pathway
0.44	GO:0035220	wing disc development
0.43	GO:0042391	regulation of membrane potential
0.36	GO:0098660	inorganic ion transmembrane transport
0.34	GO:0046662	regulation of oviposition
0.34	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.34	GO:0006836	neurotransmitter transport

0.84	GO:0005242	inward rectifier potassium channel activity
0.34	GO:0005328	neurotransmitter:sodium symporter activity
0.33	GO:0004672	protein kinase activity
0.32	GO:0008270	zinc ion binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003676	nucleic acid binding

0.36	GO:0005887	integral component of plasma membrane
0.34	GO:0043025	neuronal cell body
0.34	GO:0043005	neuron projection

tr|T1G3T4|T1G3T4_HELRO
Uncharacterized protein
Search

0.39	GO:0048731	system development
0.39	GO:0030198	extracellular matrix organization
0.39	GO:0009405	pathogenesis
0.39	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.38	GO:0009653	anatomical structure morphogenesis
0.38	GO:0030154	cell differentiation
0.38	GO:1901699	cellular response to nitrogen compound
0.38	GO:0043200	response to amino acid
0.37	GO:0007528	neuromuscular junction development
0.37	GO:0007155	cell adhesion

0.61	GO:0005201	extracellular matrix structural constituent
0.43	GO:0042302	structural constituent of cuticle
0.37	GO:0005509	calcium ion binding
0.37	GO:0048407	platelet-derived growth factor binding
0.36	GO:0008270	zinc ion binding
0.36	GO:0019901	protein kinase binding
0.36	GO:0004867	serine-type endopeptidase inhibitor activity
0.35	GO:0005044	scavenger receptor activity
0.35	GO:0046332	SMAD binding
0.35	GO:0044877	macromolecular complex binding

0.62	GO:0005581	collagen trimer
0.49	GO:0044420	extracellular matrix component
0.47	GO:0005578	proteinaceous extracellular matrix
0.38	GO:0019867	outer membrane
0.38	GO:0099080	supramolecular complex
0.37	GO:0005615	extracellular space
0.36	GO:0031594	neuromuscular junction
0.34	GO:0005783	endoplasmic reticulum
0.33	GO:0001650	fibrillar center
0.33	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex

0.33

EC:3.4.23

GO:0004190

tr|T1G3T5|T1G3T5_HELRO
Uncharacterized protein
Search

0.57	GO:0006468	protein phosphorylation
0.49	GO:0018212	peptidyl-tyrosine modification
0.38	GO:0016567	protein ubiquitination
0.38	GO:0009116	nucleoside metabolic process
0.36	GO:0007165	signal transduction
0.35	GO:0055085	transmembrane transport

0.58	GO:0004672	protein kinase activity
0.50	GO:0032559	adenyl ribonucleotide binding
0.50	GO:0008144	drug binding
0.50	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0008270	zinc ion binding
0.38	GO:0004842	ubiquitin-protein transferase activity
0.36	GO:0016874	ligase activity

0.30

GO:0016020

membrane

0.36	EC:6	GO:0016874
0.38	KEGG:R03876	GO:0004842

tr|T1G3T6|T1G3T6_HELRO
Uncharacterized protein
Search

0.74	GO:0008017	microtubule binding
0.70	GO:0005509	calcium ion binding
0.62	GO:0003779	actin binding
0.34	GO:0002162	dystroglycan binding

0.59	GO:0005856	cytoskeleton
0.30	GO:0044425	membrane part

tr|T1G3T7|T1G3T7_HELRO
Uncharacterized protein
Search

tr|T1G3T8|T1G3T8_HELRO
Uncharacterized protein
Search

0.10	Accumulation-associated protein

0.56	GO:0007155	cell adhesion
0.39	GO:0030041	actin filament polymerization
0.38	GO:0071897	DNA biosynthetic process
0.38	GO:0006260	DNA replication
0.37	GO:0006508	proteolysis
0.37	GO:0043044	ATP-dependent chromatin remodeling
0.36	GO:2000142	regulation of DNA-templated transcription, initiation
0.36	GO:0006352	DNA-templated transcription, initiation
0.36	GO:0042158	lipoprotein biosynthetic process
0.35	GO:0009405	pathogenesis

0.61	GO:0005518	collagen binding
0.46	GO:0005201	extracellular matrix structural constituent
0.40	GO:0042302	structural constituent of cuticle
0.39	GO:0003887	DNA-directed DNA polymerase activity
0.38	GO:0032559	adenyl ribonucleotide binding
0.38	GO:0004175	endopeptidase activity
0.38	GO:0017048	Rho GTPase binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0008882	[glutamate-ammonia-ligase] adenylyltransferase activity

0.54	GO:0005581	collagen trimer
0.54	GO:0005618	cell wall
0.50	GO:0005576	extracellular region
0.39	GO:0009360	DNA polymerase III complex
0.39	GO:0019867	outer membrane
0.38	GO:0005876	spindle microtubule
0.37	GO:0016514	SWI/SNF complex
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.39

EC:2.7.7.7

GO:0003887

tr|T1G3T9|T1G3T9_HELRO
Uncharacterized protein
Search

0.86	Calcium uptake protein 3, mitochondrial

0.34

GO:0006851

mitochondrial calcium ion transmembrane transport

0.70	GO:0005509	calcium ion binding
0.33	GO:0019706	protein-cysteine S-palmitoyltransferase activity

0.33	GO:0005739	mitochondrion
0.32	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.33

EC:2.3.1.225

GO:0019706

tr|T1G3U0|T1G3U0_HELRO
Uncharacterized protein
Search

0.49	GO:1903506	regulation of nucleic acid-templated transcription
0.49	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.49	GO:0010468	regulation of gene expression
0.41	GO:0006351	transcription, DNA-templated
0.35	GO:0060041	retina development in camera-type eye

0.51	GO:0003676	nucleic acid binding
0.47	GO:0046872	metal ion binding
0.44	GO:0003700	DNA binding transcription factor activity

0.46	GO:0005634	nucleus
0.36	GO:0015630	microtubule cytoskeleton
0.36	GO:0031974	membrane-enclosed lumen
0.34	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

tr|T1G3U1|T1G3U1_HELRO
Uncharacterized protein
Search

0.10	Protein still life, isoform SIF type 1

0.74	GO:0035023	regulation of Rho protein signal transduction
0.64	GO:0065009	regulation of molecular function
0.60	GO:0035556	intracellular signal transduction
0.37	GO:0051491	positive regulation of filopodium assembly
0.37	GO:0050770	regulation of axonogenesis
0.37	GO:0050803	regulation of synapse structure or activity
0.36	GO:0030036	actin cytoskeleton organization
0.35	GO:0006887	exocytosis
0.34	GO:0030259	lipid glycosylation
0.33	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0005057	signal transducer activity, downstream of receptor
0.75	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.38	GO:0005543	phospholipid binding
0.37	GO:0048365	Rac GTPase binding
0.33	GO:0003684	damaged DNA binding
0.33	GO:0005509	calcium ion binding
0.33	GO:0004930	G-protein coupled receptor activity
0.33	GO:0016758	transferase activity, transferring hexosyl groups
0.33	GO:0043565	sequence-specific DNA binding
0.32	GO:0016787	hydrolase activity

0.44	GO:0005622	intracellular
0.36	GO:0045202	synapse
0.36	GO:0030054	cell junction
0.35	GO:0099023	tethering complex
0.34	GO:0099512	supramolecular fiber
0.33	GO:0043234	protein complex
0.33	GO:0071944	cell periphery
0.33	GO:0043226	organelle
0.30	GO:0016020	membrane

0.33

GO:0016758

tr|T1G3U2|T1G3U2_HELRO
Uncharacterized protein
Search

0.21	Short-chain dehydrogenase

0.48

GO:0055114

oxidation-reduction process

0.49	GO:0016491	oxidoreductase activity
0.42	GO:0004312	fatty acid synthase activity

0.30

GO:0044425

membrane part

0.49

GO:0016491

tr|T1G3U3|T1G3U3_HELRO
Uncharacterized protein
Search

0.63	N-beta-n-acetylglucosaminyl-l-asparaginase

0.44	GO:0006517	protein deglycosylation
0.38	GO:0051604	protein maturation
0.36	GO:0006508	proteolysis
0.34	GO:0043312	neutrophil degranulation
0.32	GO:0016310	phosphorylation
0.32	GO:0055085	transmembrane transport
0.32	GO:0055114	oxidation-reduction process

0.51	GO:0016787	hydrolase activity
0.36	GO:0140096	catalytic activity, acting on a protein
0.34	GO:0043621	protein self-association
0.33	GO:0003951	NAD+ kinase activity
0.33	GO:1901265	nucleoside phosphate binding
0.33	GO:0036094	small molecule binding
0.33	GO:0097367	carbohydrate derivative binding
0.33	GO:0008144	drug binding
0.33	GO:0043168	anion binding
0.32	GO:0003676	nucleic acid binding

0.42	GO:0005764	lysosome
0.38	GO:0005615	extracellular space
0.38	GO:0005783	endoplasmic reticulum
0.34	GO:0034774	secretory granule lumen
0.34	GO:0005775	vacuolar lumen
0.34	GO:1903561	extracellular vesicle
0.30	GO:0016020	membrane

0.51	EC:3	GO:0016787
0.33	KEGG:R00104	GO:0003951

tr|T1G3U4|T1G3U4_HELRO
Uncharacterized protein
Search

0.57	Collagen triple helix repeat domain containing protein

0.42	GO:0007155	cell adhesion
0.41	GO:0032501	multicellular organismal process
0.41	GO:0009405	pathogenesis
0.40	GO:0048856	anatomical structure development
0.40	GO:0030198	extracellular matrix organization
0.40	GO:1905792	positive regulation of mechanosensory behavior
0.40	GO:1905787	regulation of detection of mechanical stimulus involved in sensory perception of touch
0.39	GO:0031646	positive regulation of neurological system process
0.39	GO:0045112	integrin biosynthetic process
0.39	GO:0007638	mechanosensory behavior

0.64	GO:0005201	extracellular matrix structural constituent
0.44	GO:0042302	structural constituent of cuticle
0.42	GO:0008201	heparin binding
0.39	GO:0043394	proteoglycan binding
0.38	GO:0048407	platelet-derived growth factor binding
0.36	GO:0030246	carbohydrate binding
0.36	GO:0032403	protein complex binding
0.34	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.34	GO:0050839	cell adhesion molecule binding
0.34	GO:0005102	receptor binding

0.64	GO:0005581	collagen trimer
0.51	GO:0044420	extracellular matrix component
0.50	GO:0005578	proteinaceous extracellular matrix
0.40	GO:0099081	supramolecular polymer
0.39	GO:0019867	outer membrane
0.37	GO:0070062	extracellular exosome
0.35	GO:0005783	endoplasmic reticulum
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0005829	cytosol
0.33	GO:0044446	intracellular organelle part

0.34

GO:0004553

tr|T1G3U5|T1G3U5_HELRO
Uncharacterized protein
Search

0.83	Tyrosine-protein kinase Src42A (inferred by orthology to a D. melanogaster protein)

0.72	GO:0018108	peptidyl-tyrosine phosphorylation
0.67	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.50	GO:0038065	collagen-activated signaling pathway
0.36	GO:0046777	protein autophosphorylation
0.36	GO:0045087	innate immune response
0.35	GO:0032502	developmental process
0.35	GO:0042127	regulation of cell proliferation
0.35	GO:0071469	cellular response to alkaline pH
0.35	GO:0060071	Wnt signaling pathway, planar cell polarity pathway
0.35	GO:0016477	cell migration

0.73	GO:0004713	protein tyrosine kinase activity
0.68	GO:0019199	transmembrane receptor protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0038064	collagen receptor activity
0.35	GO:1904929	coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway
0.35	GO:0005102	receptor binding
0.35	GO:0016462	pyrophosphatase activity
0.33	GO:0003676	nucleic acid binding

0.43	GO:0005887	integral component of plasma membrane
0.36	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.33	GO:0005737	cytoplasm
0.33	GO:0071004	U2-type prespliceosome
0.33	GO:0005685	U1 snRNP

0.73

GO:0004713

tr|T1G3U6|T1G3U6_HELRO
Uncharacterized protein
Search

0.78	Ornithine decarboxylase antizyme (Fragment)

0.72

GO:0043086

negative regulation of catalytic activity

0.85

GO:0008073

ornithine decarboxylase inhibitor activity

tr|T1G3U7|T1G3U7_HELRO
Uncharacterized protein
Search

0.49	Putative translation machinery-associated protein

0.52	GO:0075522	IRES-dependent viral translational initiation
0.51	GO:0001731	formation of translation preinitiation complex
0.50	GO:0032790	ribosome disassembly
0.49	GO:0002188	translation reinitiation
0.40	GO:0040008	regulation of growth
0.38	GO:0007049	cell cycle
0.36	GO:0006351	transcription, DNA-templated
0.36	GO:0060255	regulation of macromolecule metabolic process
0.36	GO:0031323	regulation of cellular metabolic process
0.36	GO:0051171	regulation of nitrogen compound metabolic process

0.59	GO:0003723	RNA binding
0.33	GO:0004866	endopeptidase inhibitor activity
0.33	GO:0070001	aspartic-type peptidase activity
0.33	GO:0004175	endopeptidase activity
0.33	GO:0005515	protein binding

0.51	GO:0022627	cytosolic small ribosomal subunit
0.39	GO:0005886	plasma membrane
0.33	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

tr|T1G3U8|T1G3U8_HELRO
Uncharacterized protein
Search

0.64	dual specificity protein phosphatase 8

0.79	GO:0000188	inactivation of MAPK activity
0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.36	GO:0045208	MAPK phosphatase export from nucleus
0.35	GO:0045204	MAPK export from nucleus
0.34	GO:0016310	phosphorylation
0.34	GO:1903853	regulation of stress response to copper ion
0.34	GO:0048692	negative regulation of axon extension involved in regeneration
0.33	GO:1900425	negative regulation of defense response to bacterium
0.33	GO:1900426	positive regulation of defense response to bacterium
0.33	GO:0046329	negative regulation of JNK cascade

0.79	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity
0.75	GO:0004725	protein tyrosine phosphatase activity
0.34	GO:0016301	kinase activity
0.34	GO:0008579	JUN kinase phosphatase activity
0.33	GO:0051019	mitogen-activated protein kinase binding

0.42	GO:0005654	nucleoplasm
0.36	GO:0005737	cytoplasm
0.33	GO:0097708	intracellular vesicle
0.30	GO:0031224	intrinsic component of membrane

0.79

GO:0017017

tr|T1G3U9|T1G3U9_HELRO
Uncharacterized protein
Search

0.52	Potassium voltage-gated channel protein Shaker

0.78	GO:0051260	protein homooligomerization
0.77	GO:0034765	regulation of ion transmembrane transport
0.73	GO:0071805	potassium ion transmembrane transport
0.42	GO:0007637	proboscis extension reflex
0.42	GO:0048047	mating behavior, sex discrimination
0.42	GO:0060025	regulation of synaptic activity
0.42	GO:1903351	cellular response to dopamine
0.42	GO:0045938	positive regulation of circadian sleep/wake cycle, sleep
0.42	GO:0045838	positive regulation of membrane potential
0.41	GO:0008345	larval locomotory behavior

0.78	GO:0005249	voltage-gated potassium channel activity
0.34	GO:0019870	potassium channel inhibitor activity
0.34	GO:0051393	alpha-actinin binding
0.34	GO:0097110	scaffold protein binding
0.33	GO:0019901	protein kinase binding

0.78	GO:0008076	voltage-gated potassium channel complex
0.38	GO:0043679	axon terminus
0.37	GO:0030424	axon
0.34	GO:0014704	intercalated disc
0.33	GO:0045121	membrane raft

tr|T1G3V0|T1G3V0_HELRO
Rab GDP dissociation inhibitor
Search

0.68	Rab GDP dissociation inhibitor

0.77	GO:0007264	small GTPase mediated signal transduction
0.75	GO:0043547	positive regulation of GTPase activity
0.65	GO:0015031	protein transport
0.36	GO:0099643	signal release from synapse
0.36	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.36	GO:0032259	methylation
0.35	GO:0006836	neurotransmitter transport
0.35	GO:0006744	ubiquinone biosynthetic process
0.35	GO:0001505	regulation of neurotransmitter levels
0.34	GO:0016192	vesicle-mediated transport

0.85	GO:0005093	Rab GDP-dissociation inhibitor activity
0.76	GO:0005096	GTPase activator activity
0.36	GO:0008168	methyltransferase activity
0.32	GO:0016491	oxidoreductase activity

0.49	GO:0005737	cytoplasm
0.35	GO:0098793	presynapse
0.35	GO:0097708	intracellular vesicle
0.34	GO:0012505	endomembrane system
0.34	GO:0031312	extrinsic component of organelle membrane
0.33	GO:0019866	organelle inner membrane
0.32	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.36

GO:0008168

tr|T1G3V1|T1G3V1_HELRO
Uncharacterized protein
Search

IFT88

0.93	LOW QUALITY PROTEIN: intraflagellar transport protein 88 homolog

0.51	GO:0060785	regulation of apoptosis involved in tissue homeostasis
0.51	GO:0072019	proximal convoluted tubule development
0.50	GO:0060122	inner ear receptor cell stereocilium organization
0.50	GO:1905515	non-motile cilium assembly
0.50	GO:0008589	regulation of smoothened signaling pathway
0.49	GO:0003351	epithelial cilium movement
0.49	GO:0007368	determination of left/right symmetry
0.48	GO:0045494	photoreceptor cell maintenance
0.48	GO:0042462	eye photoreceptor cell development
0.48	GO:0042073	intraciliary transport

0.38

GO:0019894

kinesin binding

0.71	GO:0005929	cilium
0.54	GO:0120038	plasma membrane bounded cell projection part
0.54	GO:0005815	microtubule organizing center
0.46	GO:0099568	cytoplasmic region
0.40	GO:0030992	intraciliary transport particle B
0.39	GO:0002080	acrosomal membrane
0.38	GO:0032421	stereocilium bundle
0.38	GO:0043005	neuron projection
0.36	GO:0005802	trans-Golgi network
0.36	GO:0098589	membrane region

tr|T1G3V2|T1G3V2_HELRO
Uncharacterized protein
Search

0.36	Cardiolipin synthase

0.68	GO:0008654	phospholipid biosynthetic process
0.34	GO:0007006	mitochondrial membrane organization
0.34	GO:0006754	ATP biosynthetic process
0.32	GO:0006518	peptide metabolic process
0.32	GO:0043604	amide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process

0.75	GO:0008444	CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity
0.34	GO:0008808	cardiolipin synthase activity
0.33	GO:0042286	glutamate-1-semialdehyde 2,1-aminomutase activity
0.33	GO:0042586	peptide deformylase activity
0.33	GO:0003735	structural constituent of ribosome

0.33	GO:0015935	small ribosomal subunit
0.33	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.75	EC:2.7.8.5	GO:0008444
0.75	KEGG:R01801	GO:0008444

tr|T1G3V3|T1G3V3_HELRO
Uncharacterized protein
Search

PAPD7

0.58	PAP associated domain containing 7

0.44	GO:0042493	response to drug
0.42	GO:0043630	ncRNA polyadenylation involved in polyadenylation-dependent ncRNA catabolic process
0.40	GO:0071044	histone mRNA catabolic process
0.40	GO:0032211	negative regulation of telomere maintenance via telomerase
0.34	GO:0006397	mRNA processing
0.34	GO:0007076	mitotic chromosome condensation
0.34	GO:0007062	sister chromatid cohesion
0.34	GO:0006629	lipid metabolic process
0.33	GO:0006302	double-strand break repair
0.33	GO:0055114	oxidation-reduction process

0.63	GO:0016779	nucleotidyltransferase activity
0.35	GO:0043221	SMC family protein binding
0.34	GO:0016853	isomerase activity
0.34	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0046872	metal ion binding

0.48	GO:0031965	nuclear membrane
0.45	GO:0005794	Golgi apparatus
0.44	GO:0005654	nucleoplasm
0.30	GO:0016021	integral component of membrane

0.63

EC:2.7.7

GO:0016779

tr|T1G3V4|T1G3V4_HELRO
Uncharacterized protein
Search

0.77	Bcl-2 homologous antagonist/killer

0.79

GO:0043065

positive regulation of apoptotic process

0.30

GO:0031224

intrinsic component of membrane

tr|T1G3V5|T1G3V5_HELRO
Uncharacterized protein
Search

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.43	GO:0007215	glutamate receptor signaling pathway
0.37	GO:0051966	regulation of synaptic transmission, glutamatergic
0.33	GO:0006182	cGMP biosynthetic process
0.32	GO:0006468	protein phosphorylation
0.32	GO:0035556	intracellular signal transduction

0.72	GO:0004930	G-protein coupled receptor activity
0.43	GO:0008066	glutamate receptor activity
0.36	GO:0016917	GABA receptor activity
0.35	GO:0030594	neurotransmitter receptor activity
0.33	GO:0004383	guanylate cyclase activity
0.32	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.54	GO:0005886	plasma membrane
0.31	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

0.33

GO:0004383

tr|T1G3V6|T1G3V6_HELRO
Uncharacterized protein
Search

0.10	Collagen, type XXII, alpha 1 (Fragment)

0.47	GO:0060414	aorta smooth muscle tissue morphogenesis
0.46	GO:2001223	negative regulation of neuron migration
0.46	GO:0030199	collagen fibril organization
0.45	GO:0035025	positive regulation of Rho protein signal transduction
0.45	GO:0018149	peptide cross-linking
0.45	GO:0043588	skin development
0.45	GO:0007179	transforming growth factor beta receptor signaling pathway
0.45	GO:0071230	cellular response to amino acid stimulus
0.45	GO:0021987	cerebral cortex development
0.45	GO:0042060	wound healing

0.67	GO:0005201	extracellular matrix structural constituent
0.47	GO:0048407	platelet-derived growth factor binding
0.45	GO:0005178	integrin binding
0.45	GO:0002020	protease binding
0.45	GO:0046332	SMAD binding
0.41	GO:0042302	structural constituent of cuticle
0.39	GO:0004867	serine-type endopeptidase inhibitor activity
0.36	GO:0042802	identical protein binding
0.36	GO:0005044	scavenger receptor activity
0.34	GO:0046872	metal ion binding

0.63	GO:0005581	collagen trimer
0.50	GO:0044420	extracellular matrix component
0.49	GO:0005578	proteinaceous extracellular matrix
0.43	GO:0099081	supramolecular polymer
0.42	GO:0005615	extracellular space
0.34	GO:0030056	hemidesmosome
0.34	GO:0005783	endoplasmic reticulum
0.33	GO:0019867	outer membrane
0.33	GO:0070013	intracellular organelle lumen
0.32	GO:0005840	ribosome

0.34

GO:0004222

tr|T1G3V7|T1G3V7_HELRO
Palmitoyltransferase
Search

0.20	Palmitoyltransferase

0.45	GO:0018345	protein palmitoylation
0.34	GO:0042144	vacuole fusion, non-autophagic
0.34	GO:0030866	cortical actin cytoskeleton organization
0.33	GO:0017157	regulation of exocytosis
0.33	GO:0030010	establishment of cell polarity
0.33	GO:1903830	magnesium ion transmembrane transport
0.33	GO:0006434	seryl-tRNA aminoacylation
0.33	GO:0006914	autophagy
0.33	GO:0045905	positive regulation of translational termination
0.33	GO:0045901	positive regulation of translational elongation

0.79	GO:0019707	protein-cysteine S-acyltransferase activity
0.79	GO:0016409	palmitoyltransferase activity
0.33	GO:0015095	magnesium ion transmembrane transporter activity
0.33	GO:0004828	serine-tRNA ligase activity
0.32	GO:0043022	ribosome binding
0.32	GO:0003743	translation initiation factor activity
0.32	GO:0003746	translation elongation factor activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0003677	DNA binding
0.32	GO:0008144	drug binding

0.42	GO:0005783	endoplasmic reticulum
0.36	GO:0005794	Golgi apparatus
0.34	GO:0070062	extracellular exosome
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0032432	actin filament bundle
0.34	GO:0030479	actin cortical patch
0.33	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.79

GO:0019707

tr|T1G3V8|T1G3V8_HELRO
Uncharacterized protein
Search

0.51	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.48	GO:0071560	cellular response to transforming growth factor beta stimulus
0.47	GO:0009653	anatomical structure morphogenesis
0.47	GO:0007492	endoderm development
0.47	GO:0007275	multicellular organism development
0.47	GO:0030154	cell differentiation
0.46	GO:0016525	negative regulation of angiogenesis
0.42	GO:0030198	extracellular matrix organization
0.41	GO:0120036	plasma membrane bounded cell projection organization
0.41	GO:0071230	cellular response to amino acid stimulus

0.68	GO:0005201	extracellular matrix structural constituent
0.44	GO:0042302	structural constituent of cuticle
0.42	GO:0001540	amyloid-beta binding
0.42	GO:0008201	heparin binding
0.40	GO:0048407	platelet-derived growth factor binding
0.36	GO:0046332	SMAD binding
0.36	GO:0005178	integrin binding
0.36	GO:0002020	protease binding
0.35	GO:0008061	chitin binding
0.34	GO:0005509	calcium ion binding

0.69	GO:0005581	collagen trimer
0.63	GO:0044420	extracellular matrix component
0.59	GO:0005578	proteinaceous extracellular matrix
0.48	GO:0005615	extracellular space
0.46	GO:0099081	supramolecular polymer
0.38	GO:0005887	integral component of plasma membrane
0.35	GO:0005788	endoplasmic reticulum lumen
0.35	GO:1903561	extracellular vesicle
0.33	GO:0019867	outer membrane

tr|T1G3V9|T1G3V9_HELRO
Uncharacterized protein
Search

0.45	Collagen triple helix repeat

0.52	GO:0030199	collagen fibril organization
0.49	GO:0048513	animal organ development
0.48	GO:0061448	connective tissue development
0.48	GO:0072359	circulatory system development
0.48	GO:0009653	anatomical structure morphogenesis
0.47	GO:0030154	cell differentiation
0.47	GO:0071363	cellular response to growth factor stimulus
0.46	GO:0007399	nervous system development
0.46	GO:0001501	skeletal system development
0.46	GO:0035295	tube development

0.67	GO:0005201	extracellular matrix structural constituent
0.53	GO:0048407	platelet-derived growth factor binding
0.46	GO:0042289	MHC class II protein binding
0.42	GO:0002020	protease binding
0.42	GO:0042802	identical protein binding
0.42	GO:0005178	integrin binding
0.42	GO:0046332	SMAD binding
0.40	GO:0042302	structural constituent of cuticle
0.40	GO:0043394	proteoglycan binding
0.39	GO:0008201	heparin binding

0.63	GO:0005581	collagen trimer
0.55	GO:0044420	extracellular matrix component
0.53	GO:0005578	proteinaceous extracellular matrix
0.48	GO:0099080	supramolecular complex
0.46	GO:0005615	extracellular space
0.37	GO:0005783	endoplasmic reticulum
0.33	GO:0031594	neuromuscular junction
0.33	GO:0019867	outer membrane
0.33	GO:0070013	intracellular organelle lumen
0.33	GO:0000139	Golgi membrane

0.32

GO:0004252

tr|T1G3W0|T1G3W0_HELRO
Uncharacterized protein
Search

tr|T1G3W1|T1G3W1_HELRO
Uncharacterized protein
Search

0.61	GO:0006508	proteolysis
0.54	GO:0030574	collagen catabolic process
0.51	GO:0001503	ossification
0.50	GO:1904707	positive regulation of vascular smooth muscle cell proliferation
0.49	GO:0035987	endodermal cell differentiation
0.49	GO:0007566	embryo implantation
0.48	GO:0060346	bone trabecula formation
0.48	GO:0001955	blood vessel maturation
0.47	GO:0060325	face morphogenesis
0.46	GO:0071230	cellular response to amino acid stimulus

0.70	GO:0004222	metalloendopeptidase activity
0.63	GO:0008270	zinc ion binding
0.37	GO:0042802	identical protein binding
0.36	GO:0004252	serine-type endopeptidase activity
0.35	GO:0001968	fibronectin binding
0.34	GO:0005044	scavenger receptor activity
0.34	GO:0032403	protein complex binding
0.33	GO:0008061	chitin binding
0.33	GO:0016746	transferase activity, transferring acyl groups
0.33	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds

0.74	GO:0031012	extracellular matrix
0.45	GO:0030017	sarcomere
0.45	GO:0005615	extracellular space
0.39	GO:0005739	mitochondrion
0.38	GO:0005886	plasma membrane
0.34	GO:1903561	extracellular vesicle
0.34	GO:0005634	nucleus
0.34	GO:1904724	tertiary granule lumen
0.33	GO:1904813	ficolin-1-rich granule lumen
0.33	GO:0005581	collagen trimer

0.70

GO:0004222

tr|T1G3W2|T1G3W2_HELRO
Uncharacterized protein
Search

CPEB2

0.83	Cytoplasmic polyadenylation element binding protein 2

0.72	GO:0006417	regulation of translation
0.40	GO:0034249	negative regulation of cellular amide metabolic process
0.39	GO:0007288	sperm axoneme assembly
0.39	GO:0007291	sperm individualization
0.39	GO:0007141	male meiosis I
0.39	GO:0032269	negative regulation of cellular protein metabolic process
0.39	GO:0008049	male courtship behavior
0.39	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
0.38	GO:0007616	long-term memory
0.38	GO:0008356	asymmetric cell division

0.84	GO:0003730	mRNA 3'-UTR binding
0.83	GO:0045182	translation regulator activity
0.37	GO:0043022	ribosome binding
0.36	GO:0008135	translation factor activity, RNA binding
0.34	GO:0042802	identical protein binding
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.40	GO:1990124	messenger ribonucleoprotein complex
0.40	GO:0043005	neuron projection
0.40	GO:0045202	synapse
0.38	GO:0044297	cell body
0.37	GO:0036477	somatodendritic compartment
0.37	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0098590	plasma membrane region
0.37	GO:0120038	plasma membrane bounded cell projection part
0.35	GO:0005634	nucleus
0.34	GO:0030054	cell junction

0.32

GO:0016740

tr|T1G3W3|T1G3W3_HELRO
Uncharacterized protein
Search

PI4K2B

0.92	Phosphatidylinositol 4-kinase type 2-beta

0.56	GO:0016310	phosphorylation
0.54	GO:0007032	endosome organization
0.53	GO:0007030	Golgi organization
0.52	GO:0046488	phosphatidylinositol metabolic process
0.51	GO:0030258	lipid modification
0.43	GO:0046474	glycerophospholipid biosynthetic process
0.41	GO:0002560	basophil mediated immunity
0.40	GO:0002276	basophil activation involved in immune response
0.39	GO:0043299	leukocyte degranulation
0.35	GO:0033339	pectoral fin development

0.59	GO:0004430	1-phosphatidylinositol 4-kinase activity
0.48	GO:0035651	AP-3 adaptor complex binding
0.39	GO:0032559	adenyl ribonucleotide binding
0.39	GO:0008144	drug binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0000287	magnesium ion binding

0.52	GO:0005765	lysosomal membrane
0.51	GO:0005802	trans-Golgi network
0.51	GO:0044221	host cell synapse
0.50	GO:0005768	endosome
0.49	GO:0072556	other organism presynaptic membrane
0.48	GO:0042734	presynaptic membrane
0.47	GO:0043025	neuronal cell body
0.46	GO:0030425	dendrite
0.45	GO:0031083	BLOC-1 complex
0.44	GO:0045121	membrane raft

0.59	EC:2.7.1.67	GO:0004430
0.59	KEGG:R03361	GO:0004430

tr|T1G3W4|T1G3W4_HELRO
Uncharacterized protein
Search

PLEC

0.71	Microtubule-actin crosslinking factor 1a

0.45	GO:0048468	cell development
0.45	GO:0035147	branch fusion, open tracheal system
0.45	GO:0035149	lumen formation, open tracheal system
0.45	GO:0030716	oocyte fate determination
0.44	GO:0016204	determination of muscle attachment site
0.44	GO:0016319	mushroom body development
0.44	GO:0007026	negative regulation of microtubule depolymerization
0.44	GO:0051491	positive regulation of filopodium assembly
0.44	GO:0045773	positive regulation of axon extension
0.44	GO:0007475	apposition of dorsal and ventral imaginal disc-derived wing surfaces

0.74	GO:0003779	actin binding
0.62	GO:0008017	microtubule binding
0.58	GO:0005509	calcium ion binding
0.39	GO:0030506	ankyrin binding
0.38	GO:0045296	cadherin binding
0.34	GO:0008307	structural constituent of muscle
0.33	GO:0004725	protein tyrosine phosphatase activity
0.32	GO:0004871	signal transducer activity
0.32	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.32	GO:0003676	nucleic acid binding

0.65	GO:0005856	cytoskeleton
0.45	GO:0005924	cell-substrate adherens junction
0.44	GO:0045169	fusome
0.44	GO:0044295	axonal growth cone
0.43	GO:0030175	filopodium
0.43	GO:0099512	supramolecular fiber
0.40	GO:0005903	brush border
0.39	GO:0030056	hemidesmosome
0.38	GO:0042383	sarcolemma
0.37	GO:0044446	intracellular organelle part

0.33

GO:0004725

tr|T1G3W5|T1G3W5_HELRO
Uncharacterized protein
Search

0.43	Collagen triple helix repeat-containing protein (Fragment)

0.37	GO:0030198	extracellular matrix organization
0.37	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.37	GO:0010951	negative regulation of endopeptidase activity
0.37	GO:0007275	multicellular organism development
0.36	GO:0009405	pathogenesis
0.36	GO:0030154	cell differentiation
0.36	GO:0009653	anatomical structure morphogenesis
0.36	GO:0003416	endochondral bone growth
0.36	GO:0009888	tissue development
0.36	GO:0006898	receptor-mediated endocytosis

0.54	GO:0005201	extracellular matrix structural constituent
0.44	GO:0042302	structural constituent of cuticle
0.37	GO:0005044	scavenger receptor activity
0.37	GO:0004867	serine-type endopeptidase inhibitor activity
0.34	GO:0008061	chitin binding
0.34	GO:0008201	heparin binding
0.33	GO:0005509	calcium ion binding
0.33	GO:0003677	DNA binding
0.32	GO:0016874	ligase activity
0.32	GO:0016798	hydrolase activity, acting on glycosyl bonds

0.64	GO:0005581	collagen trimer
0.49	GO:0044420	extracellular matrix component
0.47	GO:0005578	proteinaceous extracellular matrix
0.37	GO:0099081	supramolecular polymer
0.35	GO:0019867	outer membrane
0.35	GO:0031594	neuromuscular junction
0.34	GO:0005615	extracellular space
0.32	GO:0005694	chromosome
0.30	GO:0016021	integral component of membrane

0.32

GO:0016874

tr|T1G3W6|T1G3W6_HELRO
Uncharacterized protein
Search

BBS7

0.96	Bardet-Biedl syndrome 7 protein homolog

0.77	GO:1905515	non-motile cilium assembly
0.59	GO:1903929	primary palate development
0.59	GO:0048736	appendage development
0.58	GO:0007507	heart development
0.55	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.55	GO:0045444	fat cell differentiation
0.55	GO:0008104	protein localization
0.54	GO:0007224	smoothened signaling pathway
0.53	GO:0001654	eye development
0.53	GO:0042886	amide transport

0.57	GO:0001103	RNA polymerase II repressing transcription factor binding
0.34	GO:0004488	methylenetetrahydrofolate dehydrogenase (NADP+) activity
0.32	GO:0005216	ion channel activity

0.78	GO:0034464	BBSome
0.67	GO:0036064	ciliary basal body
0.57	GO:0005930	axoneme
0.55	GO:0001750	photoreceptor outer segment
0.53	GO:0005813	centrosome
0.45	GO:0005634	nucleus
0.36	GO:0060170	ciliary membrane
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.34	EC:1.5.1.5	GO:0004488
0.34	KEGG:R01220	GO:0004488

tr|T1G3W7|T1G3W7_HELRO
Uncharacterized protein
Search

CDK14

0.55	Cell division protein kinase

0.62	GO:0006468	protein phosphorylation
0.54	GO:0000086	G2/M transition of mitotic cell cycle
0.52	GO:0060828	regulation of canonical Wnt signaling pathway
0.49	GO:0051726	regulation of cell cycle
0.41	GO:0016055	Wnt signaling pathway
0.41	GO:0051301	cell division

0.65	GO:0004674	protein serine/threonine kinase activity
0.54	GO:0097472	cyclin-dependent protein kinase activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0030332	cyclin binding
0.38	GO:0020037	heme binding

0.57	GO:0000308	cytoplasmic cyclin-dependent protein kinase holoenzyme complex
0.46	GO:0005829	cytosol
0.44	GO:0005634	nucleus
0.41	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.65

GO:0004674

tr|T1G3W8|T1G3W8_HELRO
Uncharacterized protein
Search

0.10	Collagen-like protein (Fragment)

0.49	GO:0009405	pathogenesis
0.38	GO:0010951	negative regulation of endopeptidase activity
0.37	GO:0035124	embryonic caudal fin morphogenesis
0.36	GO:0031101	fin regeneration
0.36	GO:0006030	chitin metabolic process
0.35	GO:0048514	blood vessel morphogenesis
0.34	GO:0051276	chromosome organization

0.66	GO:0005201	extracellular matrix structural constituent
0.40	GO:0005509	calcium ion binding
0.40	GO:0042302	structural constituent of cuticle
0.38	GO:0004867	serine-type endopeptidase inhibitor activity
0.36	GO:0008061	chitin binding
0.33	GO:0046983	protein dimerization activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.58	GO:0005581	collagen trimer
0.46	GO:0019867	outer membrane
0.36	GO:0005576	extracellular region
0.34	GO:0005694	chromosome
0.30	GO:0016021	integral component of membrane

tr|T1G3W9|T1G3W9_HELRO
Uncharacterized protein
Search

tr|T1G3X0|T1G3X0_HELRO
Uncharacterized protein
Search

0.72	Glycine receptor subunit alpha-2

0.61	GO:0007165	signal transduction
0.60	GO:0034220	ion transmembrane transport
0.38	GO:0006821	chloride transport
0.36	GO:0060012	synaptic transmission, glycinergic
0.35	GO:0043200	response to amino acid
0.35	GO:0060078	regulation of postsynaptic membrane potential
0.33	GO:0019538	protein metabolic process
0.32	GO:0006355	regulation of transcription, DNA-templated
0.32	GO:0043412	macromolecule modification
0.32	GO:0016310	phosphorylation

0.75	GO:0005230	extracellular ligand-gated ion channel activity
0.70	GO:0004888	transmembrane signaling receptor activity
0.40	GO:0099095	ligand-gated anion channel activity
0.38	GO:0005254	chloride channel activity
0.37	GO:0022835	transmitter-gated channel activity
0.36	GO:0016594	glycine binding
0.33	GO:0070001	aspartic-type peptidase activity
0.33	GO:0044877	macromolecular complex binding
0.33	GO:0004674	protein serine/threonine kinase activity
0.33	GO:0140110	transcription regulator activity

0.55	GO:0005886	plasma membrane
0.41	GO:1902711	GABA-A receptor complex
0.35	GO:0098794	postsynapse
0.32	GO:0016592	mediator complex
0.30	GO:0016021	integral component of membrane

0.33

GO:0004674

tr|T1G3X1|T1G3X1_HELRO
Uncharacterized protein
Search

0.11	Glucose-dependent insulinotropic receptor

0.35

GO:0000062

fatty-acyl-CoA binding

0.33	GO:0005739	mitochondrion
0.30	GO:0044425	membrane part

tr|T1G3X2|T1G3X2_HELRO
Uncharacterized protein
Search

tr|T1G3X3|T1G3X3_HELRO
Uncharacterized protein
Search

IST1

0.71	IST1, ESCRT-III associated factor

0.65	GO:0015031	protein transport
0.52	GO:0046745	viral capsid secondary envelopment
0.51	GO:0048672	positive regulation of collateral sprouting
0.51	GO:0009838	abscission
0.47	GO:0061640	cytoskeleton-dependent cytokinesis
0.47	GO:0045862	positive regulation of proteolysis
0.44	GO:0035890	exit from host
0.42	GO:0019058	viral life cycle
0.42	GO:0007032	endosome organization
0.41	GO:0048675	axon extension

0.52	GO:0090541	MIT domain binding
0.48	GO:0045296	cadherin binding
0.45	GO:0032403	protein complex binding
0.35	GO:0042802	identical protein binding

0.50	GO:0090543	Flemming body
0.48	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.46	GO:0005813	centrosome
0.44	GO:0000785	chromatin
0.43	GO:0005829	cytosol
0.39	GO:0031410	cytoplasmic vesicle
0.38	GO:0012505	endomembrane system
0.36	GO:0070062	extracellular exosome
0.36	GO:0044428	nuclear part
0.35	GO:0031967	organelle envelope

tr|T1G3X4|T1G3X4_HELRO
Uncharacterized protein
Search

0.65	Snare protein syntaxin 1

0.74	GO:0017157	regulation of exocytosis
0.69	GO:0006886	intracellular protein transport
0.69	GO:0016192	vesicle-mediated transport
0.68	GO:0061025	membrane fusion
0.54	GO:0001956	positive regulation of neurotransmitter secretion
0.54	GO:2000463	positive regulation of excitatory postsynaptic potential
0.54	GO:1902803	regulation of synaptic vesicle transport
0.53	GO:0098693	regulation of synaptic vesicle cycle
0.51	GO:0097480	establishment of synaptic vesicle localization
0.51	GO:0061669	spontaneous neurotransmitter secretion

0.81	GO:0005484	SNAP receptor activity
0.72	GO:0000149	SNARE binding
0.50	GO:0019900	kinase binding
0.46	GO:0019869	chloride channel inhibitor activity
0.45	GO:0019855	calcium channel inhibitor activity
0.44	GO:0005102	receptor binding
0.38	GO:0017022	myosin binding
0.36	GO:0019904	protein domain specific binding

0.52	GO:0098793	presynapse
0.51	GO:0031201	SNARE complex
0.50	GO:0030424	axon
0.49	GO:0070382	exocytic vesicle
0.42	GO:0031965	nuclear membrane
0.42	GO:0030658	transport vesicle membrane
0.42	GO:0005886	plasma membrane
0.38	GO:0005652	nuclear lamina
0.36	GO:0005813	centrosome
0.35	GO:0005654	nucleoplasm

tr|T1G3X5|T1G3X5_HELRO
Uncharacterized protein
Search

0.10	Collagen triple helix repeat domain containing protein

0.46	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.44	GO:0007528	neuromuscular junction development
0.42	GO:0030198	extracellular matrix organization
0.40	GO:0007275	multicellular organism development
0.38	GO:0071230	cellular response to amino acid stimulus
0.38	GO:0009653	anatomical structure morphogenesis
0.37	GO:0009888	tissue development
0.37	GO:0060322	head development
0.36	GO:0030154	cell differentiation
0.36	GO:0010951	negative regulation of endopeptidase activity

0.67	GO:0005201	extracellular matrix structural constituent
0.41	GO:0042302	structural constituent of cuticle
0.38	GO:0048407	platelet-derived growth factor binding
0.36	GO:0004867	serine-type endopeptidase inhibitor activity
0.35	GO:0008061	chitin binding
0.34	GO:0005509	calcium ion binding
0.34	GO:0004252	serine-type endopeptidase activity
0.33	GO:0005044	scavenger receptor activity
0.33	GO:0005179	hormone activity
0.33	GO:0005518	collagen binding

0.68	GO:0005581	collagen trimer
0.65	GO:0005604	basement membrane
0.49	GO:0098645	collagen network
0.42	GO:0031594	neuromuscular junction
0.40	GO:0005615	extracellular space
0.34	GO:0019867	outer membrane
0.34	GO:0005788	endoplasmic reticulum lumen
0.33	GO:0005614	interstitial matrix
0.33	GO:1903561	extracellular vesicle
0.30	GO:0016021	integral component of membrane

0.34

GO:0004252

tr|T1G3X6|T1G3X6_HELRO
Uncharacterized protein
Search

0.47	Tyrosine-protein kinase receptor (Fragment)

0.75	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.75	GO:0018108	peptidyl-tyrosine phosphorylation
0.65	GO:0046777	protein autophosphorylation
0.60	GO:0071469	cellular response to alkaline pH
0.48	GO:0060267	positive regulation of respiratory burst
0.48	GO:0045821	positive regulation of glycolytic process
0.48	GO:0045725	positive regulation of glycogen biosynthetic process
0.47	GO:0032148	activation of protein kinase B activity
0.47	GO:0051290	protein heterotetramerization
0.47	GO:0046326	positive regulation of glucose import

0.77	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.70	GO:0043560	insulin receptor substrate binding
0.69	GO:0043548	phosphatidylinositol 3-kinase binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0051425	PTB domain binding
0.48	GO:0043559	insulin binding
0.48	GO:0031995	insulin-like growth factor II binding

0.51	GO:0005887	integral component of plasma membrane
0.48	GO:0106003	amyloid-beta complex
0.46	GO:0043235	receptor complex
0.46	GO:0005901	caveola
0.45	GO:1902911	protein kinase complex
0.43	GO:0005635	nuclear envelope
0.41	GO:0031981	nuclear lumen
0.36	GO:0032809	neuronal cell body membrane
0.36	GO:0032590	dendrite membrane
0.35	GO:0009897	external side of plasma membrane

0.77

GO:0004714

tr|T1G3X7|T1G3X7_HELRO
Uncharacterized protein
Search

0.88	Neurotransmitter-gated ion-channel

0.79	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.45	GO:0007271	synaptic transmission, cholinergic

0.82	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0099600	transmembrane receptor activity
0.34	GO:0008146	sulfotransferase activity

0.79	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.35	GO:0005892	acetylcholine-gated channel complex

0.34

GO:0008146

tr|T1G3X8|T1G3X8_HELRO
Signal recognition particle 9 kDa protein
Search

SRP9

0.81	Signal recognition particle protein (Fragment)

0.80	GO:0045900	negative regulation of translational elongation
0.75	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.44	GO:0065002	intracellular protein transmembrane transport

0.78	GO:0008312	7S RNA binding
0.47	GO:0005047	signal recognition particle binding
0.33	GO:0005515	protein binding
0.32	GO:0016787	hydrolase activity

0.78	GO:0005786	signal recognition particle, endoplasmic reticulum targeting
0.47	GO:0005785	signal recognition particle receptor complex
0.36	GO:0070062	extracellular exosome
0.35	GO:0005829	cytosol

0.32

GO:0016787

tr|T1G3X9|T1G3X9_HELRO
Uncharacterized protein
Search

tr|T1G3Y0|T1G3Y0_HELRO
Uncharacterized protein
Search

0.38	GO:2001141	regulation of RNA biosynthetic process
0.38	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.38	GO:0010468	regulation of gene expression
0.33	GO:0007018	microtubule-based movement

0.51	GO:0003676	nucleic acid binding
0.44	GO:0008270	zinc ion binding
0.35	GO:0003700	DNA binding transcription factor activity
0.33	GO:0003777	microtubule motor activity
0.33	GO:0008017	microtubule binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.42	GO:0005634	nucleus
0.33	GO:0005874	microtubule
0.30	GO:0031224	intrinsic component of membrane

tr|T1G3Y1|T1G3Y1_HELRO
Uncharacterized protein
Search

0.66	Collagen type XV alpha 1 chain

0.72	GO:0007155	cell adhesion
0.47	GO:0014899	cardiac muscle atrophy
0.46	GO:0014732	skeletal muscle atrophy
0.46	GO:0048468	cell development
0.46	GO:2001046	positive regulation of integrin-mediated signaling pathway
0.46	GO:0030198	extracellular matrix organization
0.45	GO:0048731	system development
0.44	GO:0000902	cell morphogenesis
0.43	GO:0032990	cell part morphogenesis
0.42	GO:0006928	movement of cell or subcellular component

0.62	GO:0005198	structural molecule activity
0.39	GO:0030246	carbohydrate binding
0.32	GO:0046872	metal ion binding

0.77	GO:0005581	collagen trimer
0.74	GO:0031012	extracellular matrix
0.44	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.30	GO:0016020	membrane

tr|T1G3Y2|T1G3Y2_HELRO
Uncharacterized protein
Search

MRPL38

0.84	Mitochondrial ribosomal protein L38

0.35	GO:0009617	response to bacterium
0.34	GO:0016573	histone acetylation
0.34	GO:0015074	DNA integration
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.37	GO:0016887	ATPase activity
0.36	GO:0008270	zinc ion binding
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0004402	histone acetyltransferase activity
0.34	GO:0008289	lipid binding
0.34	GO:0003712	transcription cofactor activity
0.32	GO:0003676	nucleic acid binding

0.59	GO:0005840	ribosome
0.46	GO:0005759	mitochondrial matrix
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.37

GO:0016887

tr|T1G3Y3|T1G3Y3_HELRO
Uncharacterized protein
Search

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.51	GO:0008344	adult locomotory behavior
0.47	GO:0008345	larval locomotory behavior
0.46	GO:0002209	behavioral defense response
0.34	GO:0035556	intracellular signal transduction
0.33	GO:0046854	phosphatidylinositol phosphorylation
0.32	GO:0055085	transmembrane transport

0.78	GO:0008528	G-protein coupled peptide receptor activity
0.32	GO:0016301	kinase activity

0.44	GO:0005887	integral component of plasma membrane
0.33	GO:0005741	mitochondrial outer membrane

tr|T1G3Y4|T1G3Y4_HELRO
Uncharacterized protein
Search

0.39	GO:0032509	endosome transport via multivesicular body sorting pathway
0.35	GO:0006468	protein phosphorylation

0.39	GO:0043130	ubiquitin binding
0.35	GO:0004672	protein kinase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.40	GO:0000814	ESCRT II complex
0.30	GO:0031224	intrinsic component of membrane

tr|T1G3Y5|T1G3Y5_HELRO
Uncharacterized protein
Search

KDM4A

0.84	JmjC domain-containing histone demethylation protein 3C

0.48	GO:0070544	histone H3-K36 demethylation
0.47	GO:0032259	methylation
0.46	GO:0033169	histone H3-K9 demethylation
0.40	GO:0010628	positive regulation of gene expression
0.34	GO:0045892	negative regulation of transcription, DNA-templated
0.34	GO:0046856	phosphatidylinositol dephosphorylation
0.34	GO:0055114	oxidation-reduction process
0.34	GO:0048514	blood vessel morphogenesis
0.33	GO:0006351	transcription, DNA-templated

0.48	GO:0051864	histone demethylase activity (H3-K36 specific)
0.47	GO:0008168	methyltransferase activity
0.46	GO:0032454	histone demethylase activity (H3-K9 specific)
0.43	GO:0046872	metal ion binding
0.38	GO:0003676	nucleic acid binding
0.32	GO:0016787	hydrolase activity

0.61	GO:0005634	nucleus
0.42	GO:0000792	heterochromatin
0.30	GO:0031224	intrinsic component of membrane

0.48

EC:1.14.11.27

GO:0051864

tr|T1G3Y6|T1G3Y6_HELRO
Uncharacterized protein
Search

0.42	Trifunctional nucleotide phosphoesterase protein YfkN

0.75	GO:0009166	nucleotide catabolic process
0.39	GO:0016311	dephosphorylation
0.34	GO:0080009	mRNA methylation
0.34	GO:0043547	positive regulation of GTPase activity
0.33	GO:0006886	intracellular protein transport

0.51	GO:0016787	hydrolase activity
0.51	GO:1901265	nucleoside phosphate binding
0.49	GO:0036094	small molecule binding
0.35	GO:0016422	mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity
0.34	GO:0005096	GTPase activator activity
0.32	GO:0046872	metal ion binding

0.34	GO:0017119	Golgi transport complex
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.51

GO:0016787

tr|T1G3Y7|T1G3Y7_HELRO
Uncharacterized protein
Search

MAPKAPK2

0.88	Mitogen-activated protein kinase-activated protein kinase 2a

0.70	GO:0055113	epiboly involved in gastrulation with mouth forming second
0.63	GO:0006468	protein phosphorylation
0.48	GO:0048010	vascular endothelial growth factor receptor signaling pathway
0.48	GO:0035924	cellular response to vascular endothelial growth factor stimulus
0.46	GO:0018209	peptidyl-serine modification
0.46	GO:0006954	inflammatory response
0.40	GO:0035556	intracellular signal transduction

0.68	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0051019	mitogen-activated protein kinase binding
0.48	GO:0010857	calcium-dependent protein kinase activity
0.46	GO:0005516	calmodulin binding
0.41	GO:0004871	signal transducer activity

0.40	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm

0.68

GO:0004674

tr|T1G3Y8|T1G3Y8_HELRO
Uncharacterized protein
Search

0.48	Nuclear factor I X

0.65	GO:0006260	DNA replication
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.42	GO:1902680	positive regulation of RNA biosynthetic process
0.42	GO:0042475	odontogenesis of dentin-containing tooth
0.42	GO:1902679	negative regulation of RNA biosynthetic process
0.36	GO:0048741	skeletal muscle fiber development
0.35	GO:0007608	sensory perception of smell

0.60	GO:0003700	DNA binding transcription factor activity
0.54	GO:0003677	DNA binding
0.40	GO:0001067	regulatory region nucleic acid binding
0.34	GO:0003993	acid phosphatase activity
0.33	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.38	GO:0031974	membrane-enclosed lumen
0.36	GO:0043232	intracellular non-membrane-bounded organelle
0.36	GO:0044446	intracellular organelle part

0.34

EC:3.1.3.2

GO:0003993

tr|T1G3Y9|T1G3Y9_HELRO
Uncharacterized protein
Search

0.10	Phosphatidylethanolamine-binding protein 4 (Fragment)

0.80	GO:0048573	photoperiodism, flowering
0.78	GO:0009909	regulation of flower development
0.41	GO:0048572	short-day photoperiodism
0.40	GO:0048506	regulation of timing of meristematic phase transition
0.40	GO:0010229	inflorescence development

0.80	GO:0008429	phosphatidylethanolamine binding
0.33	GO:0005515	protein binding

0.34	GO:0070062	extracellular exosome
0.34	GO:0005764	lysosome
0.30	GO:0016021	integral component of membrane

tr|T1G3Z0|T1G3Z0_HELRO
Uncharacterized protein
Search

0.23	Collagen triple helix repeat protein (Fragment)

0.49	GO:0030198	extracellular matrix organization
0.46	GO:0007275	multicellular organism development
0.46	GO:0071230	cellular response to amino acid stimulus
0.46	GO:0009653	anatomical structure morphogenesis
0.45	GO:0009888	tissue development
0.45	GO:0042060	wound healing
0.45	GO:0051239	regulation of multicellular organismal process
0.44	GO:0097435	supramolecular fiber organization
0.43	GO:0045595	regulation of cell differentiation
0.43	GO:0051093	negative regulation of developmental process

0.72	GO:0005201	extracellular matrix structural constituent
0.48	GO:0048407	platelet-derived growth factor binding
0.43	GO:0002020	protease binding
0.42	GO:0046332	SMAD binding
0.41	GO:0042302	structural constituent of cuticle
0.41	GO:0005178	integrin binding
0.40	GO:0043394	proteoglycan binding
0.40	GO:0008201	heparin binding
0.37	GO:0042802	identical protein binding
0.35	GO:0004867	serine-type endopeptidase inhibitor activity

0.68	GO:0005581	collagen trimer
0.58	GO:0044420	extracellular matrix component
0.55	GO:0005578	proteinaceous extracellular matrix
0.46	GO:0099081	supramolecular polymer
0.44	GO:0005615	extracellular space
0.35	GO:0005783	endoplasmic reticulum
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0005694	chromosome
0.33	GO:0019867	outer membrane
0.33	GO:0042383	sarcolemma

0.32

EC:2.5 EC:2.5.1

GO:0016765

tr|T1G3Z1|T1G3Z1_HELRO
Uncharacterized protein
Search

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.43	GO:0072137	condensed mesenchymal cell proliferation
0.42	GO:0072006	nephron development
0.37	GO:0060122	inner ear receptor cell stereocilium organization
0.36	GO:0007605	sensory perception of sound
0.36	GO:0007626	locomotory behavior

0.70

GO:0005509

calcium ion binding

0.56	GO:0005886	plasma membrane
0.37	GO:0032420	stereocilium
0.30	GO:0044425	membrane part

tr|T1G3Z2|T1G3Z2_HELRO
Uncharacterized protein
Search

0.10	ABC transporter ATP-binding protein (Fragment)

0.40	GO:0009405	pathogenesis
0.39	GO:0061304	retinal blood vessel morphogenesis
0.38	GO:0001569	branching involved in blood vessel morphogenesis
0.38	GO:0071711	basement membrane organization
0.38	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.38	GO:0061333	renal tubule morphogenesis
0.38	GO:0007528	neuromuscular junction development
0.37	GO:0071230	cellular response to amino acid stimulus
0.37	GO:0007420	brain development
0.36	GO:0006898	receptor-mediated endocytosis

0.61	GO:0005201	extracellular matrix structural constituent
0.48	GO:0042302	structural constituent of cuticle
0.38	GO:0048407	platelet-derived growth factor binding
0.38	GO:0005044	scavenger receptor activity
0.36	GO:0005509	calcium ion binding
0.35	GO:0046982	protein heterodimerization activity
0.35	GO:0000155	phosphorelay sensor kinase activity
0.35	GO:0003743	translation initiation factor activity
0.34	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.34	GO:0032555	purine ribonucleotide binding

0.61	GO:0005581	collagen trimer
0.47	GO:0005604	basement membrane
0.38	GO:0098645	collagen network
0.38	GO:0001650	fibrillar center
0.38	GO:0019867	outer membrane
0.38	GO:0005654	nucleoplasm
0.36	GO:0005615	extracellular space
0.35	GO:0090575	RNA polymerase II transcription factor complex
0.35	GO:1902493	acetyltransferase complex
0.35	GO:0055029	nuclear DNA-directed RNA polymerase complex

0.35

EC:2.7.3

GO:0000155

tr|T1G3Z3|T1G3Z3_HELRO
Uncharacterized protein
Search

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.40	GO:0098916	anterograde trans-synaptic signaling
0.38	GO:0007631	feeding behavior

0.72	GO:0004930	G-protein coupled receptor activity
0.59	GO:0016500	protein-hormone receptor activity
0.40	GO:0042923	neuropeptide binding
0.37	GO:0001653	peptide receptor activity

0.38	GO:0043005	neuron projection
0.36	GO:0005887	integral component of plasma membrane

tr|T1G3Z4|T1G3Z4_HELRO
Uncharacterized protein
Search

0.65	Mitochondrial ATP synthase subunit epsilon

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.69	GO:0099132	ATP hydrolysis coupled cation transmembrane transport

0.72

GO:0046933

proton-transporting ATP synthase activity, rotational mechanism

0.84	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)
0.30	GO:0016021	integral component of membrane

tr|T1G3Z5|T1G3Z5_HELRO
Uncharacterized protein
Search

tr|T1G3Z6|T1G3Z6_HELRO
Uncharacterized protein
Search

0.50	GO:0021681	cerebellar granular layer development
0.49	GO:0021702	cerebellar Purkinje cell differentiation
0.49	GO:0002931	response to ischemia
0.49	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.48	GO:0043524	negative regulation of neuron apoptotic process
0.37	GO:0006915	apoptotic process
0.34	GO:0015689	molybdate ion transport

0.34	GO:0015098	molybdate ion transmembrane transporter activity
0.33	GO:0005515	protein binding

0.47	GO:0045121	membrane raft
0.44	GO:0005794	Golgi apparatus
0.43	GO:0005783	endoplasmic reticulum
0.37	GO:0045211	postsynaptic membrane
0.36	GO:0030054	cell junction
0.30	GO:0016021	integral component of membrane

tr|T1G3Z7|T1G3Z7_HELRO
Uncharacterized protein
Search

0.39	GO:0016973	poly(A)+ mRNA export from nucleus
0.38	GO:0045944	positive regulation of transcription by RNA polymerase II
0.34	GO:0002376	immune system process
0.34	GO:0006606	protein import into nucleus
0.34	GO:0048477	oogenesis
0.34	GO:0007283	spermatogenesis
0.33	GO:0007275	multicellular organism development

0.49	GO:0003676	nucleic acid binding
0.34	GO:0016866	intramolecular transferase activity
0.33	GO:0016746	transferase activity, transferring acyl groups
0.32	GO:0005515	protein binding

0.48	GO:0005635	nuclear envelope
0.44	GO:0005829	cytosol
0.41	GO:0031090	organelle membrane
0.40	GO:0070390	transcription export complex 2
0.39	GO:0034399	nuclear periphery
0.33	GO:0005654	nucleoplasm
0.30	GO:0016021	integral component of membrane

0.34

EC:5.4

GO:0016866

tr|T1G3Z8|T1G3Z8_HELRO
Uncharacterized protein
Search

PTPN3

0.60	Tyrosine-protein phosphatase non-receptor type

0.75	GO:0035335	peptidyl-tyrosine dephosphorylation
0.52	GO:0098902	regulation of membrane depolarization during action potential
0.52	GO:0051045	negative regulation of membrane protein ectodomain proteolysis
0.50	GO:2000649	regulation of sodium ion transmembrane transporter activity
0.47	GO:0045930	negative regulation of mitotic cell cycle
0.35	GO:0097421	liver regeneration
0.35	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway
0.33	GO:0006468	protein phosphorylation

0.75	GO:0004725	protein tyrosine phosphatase activity
0.60	GO:0008092	cytoskeletal protein binding
0.50	GO:0017080	sodium channel regulator activity
0.50	GO:0001784	phosphotyrosine residue binding
0.50	GO:0051117	ATPase binding
0.36	GO:0050254	rhodopsin kinase activity

0.64	GO:0005856	cytoskeleton
0.47	GO:0009898	cytoplasmic side of plasma membrane
0.43	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.75

GO:0004725

tr|T1G3Z9|T1G3Z9_HELRO
Uncharacterized protein
Search

0.41	G-protein coupled receptor

0.71	GO:0007218	neuropeptide signaling pathway
0.50	GO:0030536	larval feeding behavior
0.49	GO:0007194	negative regulation of adenylate cyclase activity
0.36	GO:0007217	tachykinin receptor signaling pathway
0.34	GO:0070647	protein modification by small protein conjugation or removal
0.33	GO:0006508	proteolysis
0.33	GO:0009190	cyclic nucleotide biosynthetic process
0.32	GO:0006355	regulation of transcription, DNA-templated
0.32	GO:0007275	multicellular organism development
0.32	GO:0010467	gene expression

0.74	GO:0004983	neuropeptide Y receptor activity
0.53	GO:0042263	neuropeptide F receptor activity
0.36	GO:0004995	tachykinin receptor activity
0.33	GO:0017056	structural constituent of nuclear pore
0.33	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.33	GO:0031683	G-protein beta/gamma-subunit complex binding
0.33	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor
0.33	GO:0008080	N-acetyltransferase activity
0.33	GO:0016849	phosphorus-oxygen lyase activity

0.42	GO:0005887	integral component of plasma membrane
0.33	GO:0043231	intracellular membrane-bounded organelle
0.32	GO:0012505	endomembrane system
0.32	GO:0044444	cytoplasmic part
0.32	GO:0044446	intracellular organelle part
0.32	GO:0032991	macromolecular complex
0.32	GO:0031975	envelope
0.32	GO:0043232	intracellular non-membrane-bounded organelle

0.33	EC:6.3.5	GO:0016884
0.33	KEGG:R03876	GO:0004842

tr|T1G400|T1G400_HELRO
Uncharacterized protein
Search

0.86	Paired domain transcription factor variant A

0.70	GO:0007275	multicellular organism development
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.42	GO:0035883	enteroendocrine cell differentiation
0.41	GO:0060322	head development
0.40	GO:0051254	positive regulation of RNA metabolic process
0.40	GO:0010557	positive regulation of macromolecule biosynthetic process
0.40	GO:0031328	positive regulation of cellular biosynthetic process

0.60	GO:0043565	sequence-specific DNA binding
0.40	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.38	GO:0070410	co-SMAD binding
0.38	GO:0071837	HMG box domain binding
0.38	GO:0070412	R-SMAD binding
0.38	GO:0035035	histone acetyltransferase binding
0.37	GO:0001047	core promoter binding
0.37	GO:0031625	ubiquitin protein ligase binding
0.37	GO:0019901	protein kinase binding
0.37	GO:0001012	RNA polymerase II regulatory region DNA binding

0.61	GO:0005634	nucleus
0.36	GO:0005829	cytosol
0.36	GO:0070013	intracellular organelle lumen
0.36	GO:0000785	chromatin
0.34	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

0.34

GO:0004842

tr|T1G401|T1G401_HELRO
Uncharacterized protein
Search

0.61	Ras-specific guanine nucleotide-releasing factor RalGPS2

0.77	GO:0007264	small GTPase mediated signal transduction
0.70	GO:0032485	regulation of Ral protein signal transduction
0.66	GO:0065009	regulation of molecular function

0.75	GO:0005085	guanyl-nucleotide exchange factor activity
0.51	GO:0017160	Ral GTPase binding

0.45	GO:0005622	intracellular
0.34	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

tr|T1G402|T1G402_HELRO
Uncharacterized protein
Search

RRS1

0.71	Ribosome biogenesis regulatory protein homolog

0.67	GO:0042254	ribosome biogenesis
0.53	GO:1902570	protein localization to nucleolus
0.51	GO:1901796	regulation of signal transduction by p53 class mediator
0.51	GO:0007080	mitotic metaphase plate congression
0.47	GO:0022618	ribonucleoprotein complex assembly
0.47	GO:0033750	ribosome localization
0.47	GO:0071428	rRNA-containing ribonucleoprotein complex export from nucleus
0.46	GO:0070925	organelle assembly
0.43	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.42	GO:0016072	rRNA metabolic process

0.49	GO:0008097	5S rRNA binding
0.34	GO:0005515	protein binding
0.34	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.32	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.32	GO:0046872	metal ion binding
0.32	GO:0003677	DNA binding

0.61	GO:0005634	nucleus
0.48	GO:0000793	condensed chromosome
0.46	GO:0030687	preribosome, large subunit precursor
0.46	GO:0031974	membrane-enclosed lumen
0.42	GO:0044446	intracellular organelle part
0.39	GO:0005783	endoplasmic reticulum
0.34	GO:0035032	phosphatidylinositol 3-kinase complex, class III
0.33	GO:0005773	vacuole
0.33	GO:0098805	whole membrane
0.33	GO:0098588	bounding membrane of organelle

0.34

EC:1.13.11

GO:0016702

tr|T1G403|T1G403_HELRO
Uncharacterized protein
Search

tr|T1G404|T1G404_HELRO
Uncharacterized protein
Search

0.59	GO:0016573	histone acetylation
0.43	GO:0006338	chromatin remodeling
0.41	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.41	GO:1903506	regulation of nucleic acid-templated transcription
0.40	GO:0010468	regulation of gene expression
0.39	GO:0006413	translational initiation
0.38	GO:1905533	negative regulation of leucine import across plasma membrane
0.38	GO:1902680	positive regulation of RNA biosynthetic process
0.38	GO:0010515	negative regulation of induction of conjugation with cellular fusion
0.38	GO:0061647	histone H3-K9 modification

0.60	GO:0004402	histone acetyltransferase activity
0.53	GO:0046982	protein heterodimerization activity
0.41	GO:0003682	chromatin binding
0.41	GO:0042393	histone binding
0.40	GO:0046872	metal ion binding
0.40	GO:0003743	translation initiation factor activity
0.38	GO:0003677	DNA binding
0.37	GO:0140033	acetylation-dependent protein binding
0.37	GO:0030554	adenyl nucleotide binding
0.37	GO:0032555	purine ribonucleotide binding

0.58	GO:0046695	SLIK (SAGA-like) complex
0.57	GO:0000124	SAGA complex
0.44	GO:0000790	nuclear chromatin
0.40	GO:1904949	ATPase complex
0.37	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex
0.36	GO:0000775	chromosome, centromeric region
0.36	GO:0005786	signal recognition particle, endoplasmic reticulum targeting
0.35	GO:0005829	cytosol

0.60

GO:0004402

tr|T1G405|T1G405_HELRO
Uncharacterized protein
Search

FBXL7

0.95	F-box and leucine rich repeat protein 7

0.84	GO:0000086	G2/M transition of mitotic cell cycle
0.83	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
0.78	GO:0008283	cell proliferation
0.73	GO:0016567	protein ubiquitination
0.48	GO:0045571	negative regulation of imaginal disc growth
0.48	GO:0007449	proximal/distal pattern formation, imaginal disc
0.47	GO:0035330	regulation of hippo signaling
0.43	GO:0032880	regulation of protein localization
0.42	GO:0010265	SCF complex assembly
0.40	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle

0.45	GO:0004842	ubiquitin-protein transferase activity
0.36	GO:0005515	protein binding

0.83	GO:0019005	SCF ubiquitin ligase complex
0.76	GO:0005813	centrosome
0.45	GO:0045177	apical part of cell
0.43	GO:0005911	cell-cell junction
0.38	GO:0005829	cytosol
0.33	GO:0005634	nucleus

0.45

GO:0004842

tr|T1G406|T1G406_HELRO
Uncharacterized protein
Search

MLEC

0.75	malectin-A

0.36	GO:0016310	phosphorylation
0.35	GO:0032392	DNA geometric change
0.35	GO:0006260	DNA replication
0.35	GO:0006310	DNA recombination
0.35	GO:0006281	DNA repair
0.34	GO:0043312	neutrophil degranulation
0.34	GO:0005975	carbohydrate metabolic process
0.34	GO:0060271	cilium assembly
0.34	GO:0042953	lipoprotein transport
0.33	GO:0006457	protein folding

0.46	GO:0019899	enzyme binding
0.37	GO:0043140	ATP-dependent 3'-5' DNA helicase activity
0.36	GO:0016301	kinase activity
0.35	GO:0030246	carbohydrate binding
0.35	GO:0005509	calcium ion binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0008289	lipid binding
0.33	GO:0003676	nucleic acid binding

0.35	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0035579	specific granule membrane
0.34	GO:0035869	ciliary transition zone
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1G407|T1G407_HELRO
Uncharacterized protein
Search

0.44	Eosinophil chemotactic cytokine

0.67	GO:0006030	chitin metabolic process
0.60	GO:0005975	carbohydrate metabolic process
0.47	GO:1901072	glucosamine-containing compound catabolic process
0.44	GO:0045766	positive regulation of angiogenesis
0.44	GO:0006026	aminoglycan catabolic process
0.43	GO:0042737	drug catabolic process
0.38	GO:0006954	inflammatory response
0.38	GO:0090197	positive regulation of chemokine secretion
0.38	GO:0044245	polysaccharide digestion
0.37	GO:0072606	interleukin-8 secretion

0.76	GO:0008061	chitin binding
0.64	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.36	GO:0019900	kinase binding
0.35	GO:0030246	carbohydrate binding
0.34	GO:0061783	peptidoglycan muralytic activity
0.33	GO:0004252	serine-type endopeptidase activity
0.31	GO:0022857	transmembrane transporter activity

0.60	GO:0005576	extracellular region
0.36	GO:0012505	endomembrane system
0.35	GO:0060205	cytoplasmic vesicle lumen
0.34	GO:0099503	secretory vesicle
0.34	GO:0005764	lysosome
0.30	GO:0016020	membrane

0.64

GO:0004553

tr|T1G408|T1G408_HELRO
Uncharacterized protein
Search

0.70	GO:0000904	cell morphogenesis involved in differentiation
0.63	GO:0001654	eye development
0.62	GO:0014002	astrocyte development
0.62	GO:0007601	visual perception
0.60	GO:0031581	hemidesmosome assembly
0.59	GO:0022617	extracellular matrix disassembly
0.55	GO:0031589	cell-substrate adhesion
0.55	GO:0006928	movement of cell or subcellular component
0.54	GO:0055016	hypochord development
0.53	GO:0007634	optokinetic behavior

0.56	GO:0005201	extracellular matrix structural constituent
0.37	GO:0004871	signal transducer activity
0.36	GO:0016849	phosphorus-oxygen lyase activity
0.36	GO:0005509	calcium ion binding
0.33	GO:1901265	nucleoside phosphate binding
0.33	GO:0036094	small molecule binding

0.68	GO:0005604	basement membrane
0.38	GO:0005788	endoplasmic reticulum lumen
0.38	GO:0070062	extracellular exosome
0.38	GO:0005882	intermediate filament
0.36	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.36

GO:0016849

tr|T1G409|T1G409_HELRO
Uncharacterized protein
Search

RAB30

0.54	ADP ribosylation factor

0.52	GO:0007030	Golgi organization
0.46	GO:0046528	imaginal disc fusion
0.45	GO:0007390	germ-band shortening
0.45	GO:0008258	head involution
0.45	GO:0007391	dorsal closure
0.35	GO:0032482	Rab protein signal transduction
0.33	GO:0016192	vesicle-mediated transport

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005515	protein binding

0.55	GO:0005802	trans-Golgi network
0.52	GO:0005801	cis-Golgi network
0.51	GO:0031985	Golgi cisterna
0.42	GO:0045202	synapse
0.42	GO:0005768	endosome
0.34	GO:0000139	Golgi membrane

tr|T1G410|T1G410_HELRO
Uncharacterized protein
Search

0.62	GO:0006468	protein phosphorylation
0.34	GO:0034968	histone lysine methylation
0.33	GO:0001822	kidney development
0.32	GO:0006259	DNA metabolic process
0.32	GO:0051716	cellular response to stimulus
0.32	GO:0006396	RNA processing
0.32	GO:0006950	response to stress
0.32	GO:0001522	pseudouridine synthesis
0.32	GO:0016072	rRNA metabolic process
0.32	GO:0007049	cell cycle

0.62	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0018024	histone-lysine N-methyltransferase activity
0.32	GO:0004930	G-protein coupled receptor activity
0.32	GO:0030983	mismatched DNA binding
0.32	GO:0003684	damaged DNA binding
0.32	GO:0009982	pseudouridine synthase activity
0.31	GO:0003723	RNA binding

0.33	GO:0005634	nucleus
0.32	GO:0030688	preribosome, small subunit precursor
0.30	GO:0016020	membrane

0.34

GO:0018024

tr|T1G411|T1G411_HELRO
Uncharacterized protein
Search

0.74	GO:0070588	calcium ion transmembrane transport
0.68	GO:0034765	regulation of ion transmembrane transport
0.45	GO:0051899	membrane depolarization
0.44	GO:0045760	positive regulation of action potential
0.44	GO:0043051	regulation of pharyngeal pumping
0.41	GO:0070509	calcium ion import
0.39	GO:0019228	neuronal action potential
0.37	GO:0035725	sodium ion transmembrane transport
0.34	GO:0030488	tRNA methylation

0.79	GO:0005245	voltage-gated calcium channel activity
0.38	GO:0005248	voltage-gated sodium channel activity
0.36	GO:0016428	tRNA (cytosine-5-)-methyltransferase activity
0.33	GO:0003723	RNA binding

0.78

GO:0005891

voltage-gated calcium channel complex

0.36

GO:0016428

tr|T1G412|T1G412_HELRO
Phosphoglycerate kinase
Search

0.47	Phosphoglycerate kinase

0.71	GO:0006757	ATP generation from ADP
0.69	GO:0006090	pyruvate metabolic process
0.68	GO:0016052	carbohydrate catabolic process
0.67	GO:0019362	pyridine nucleotide metabolic process
0.41	GO:0031639	plasminogen activation
0.41	GO:0001666	response to hypoxia
0.41	GO:0030317	flagellated sperm motility
0.40	GO:0036294	cellular response to decreased oxygen levels
0.40	GO:0016525	negative regulation of angiogenesis
0.39	GO:0030855	epithelial cell differentiation

0.79	GO:0004618	phosphoglycerate kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0047134	protein-disulfide reductase activity

0.42	GO:0035686	sperm fibrous sheath
0.40	GO:0005737	cytoplasm
0.40	GO:0005615	extracellular space
0.40	GO:0045121	membrane raft
0.36	GO:1903561	extracellular vesicle
0.34	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.79	EC:2.7.2.3	GO:0004618
0.79	KEGG:R01512	GO:0004618

tr|T1G413|T1G413_HELRO
Uncharacterized protein
Search

tr|T1G414|T1G414_HELRO
Uncharacterized protein
Search

0.54	cAMP-dependent protein kinase catalytic subunit PRKX

0.63	GO:0006468	protein phosphorylation
0.44	GO:0060562	epithelial tube morphogenesis
0.44	GO:0035120	post-embryonic appendage morphogenesis
0.44	GO:0035114	imaginal disc-derived appendage morphogenesis
0.43	GO:0035220	wing disc development
0.43	GO:0048563	post-embryonic animal organ morphogenesis
0.43	GO:0048707	instar larval or pupal morphogenesis
0.43	GO:0007552	metamorphosis
0.38	GO:2000696	regulation of epithelial cell differentiation involved in kidney development
0.38	GO:0001935	endothelial cell proliferation

0.69	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0060089	molecular transducer activity
0.33	GO:0005515	protein binding

0.36	GO:0045171	intercellular bridge
0.34	GO:0005829	cytosol
0.34	GO:0005952	cAMP-dependent protein kinase complex
0.34	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.69

GO:0004674

tr|T1G415|T1G415_HELRO
Uncharacterized protein
Search

tr|T1G416|T1G416_HELRO
Uncharacterized protein
Search

tr|T1G417|T1G417_HELRO
Uncharacterized protein
Search

tr|T1G418|T1G418_HELRO
Uncharacterized protein
Search

COMMD4

0.96	COMM domain-containing protein 4

0.40	GO:0006351	transcription, DNA-templated
0.39	GO:2001141	regulation of RNA biosynthetic process
0.39	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.39	GO:0010468	regulation of gene expression
0.39	GO:0035023	regulation of Rho protein signal transduction
0.37	GO:0006281	DNA repair
0.37	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.37	GO:0065009	regulation of molecular function

0.39	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.37	GO:0004519	endonuclease activity
0.35	GO:0003677	DNA binding

0.47	GO:0005737	cytoplasm
0.41	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|T1G419|T1G419_HELRO
Uncharacterized protein
Search

BTBD9

0.71	BTB/POZ domain-containing protein 9

0.86	GO:0042748	circadian sleep/wake cycle, non-REM sleep
0.85	GO:1900242	regulation of synaptic vesicle endocytosis
0.85	GO:0060586	multicellular organismal iron ion homeostasis
0.84	GO:0042428	serotonin metabolic process
0.83	GO:0008344	adult locomotory behavior
0.83	GO:0050951	sensory perception of temperature stimulus
0.81	GO:0007616	long-term memory
0.65	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.65	GO:0050804	modulation of chemical synaptic transmission
0.62	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process

0.63

GO:0031625

ubiquitin protein ligase binding

0.66	GO:0019005	SCF ubiquitin ligase complex
0.43	GO:0005737	cytoplasm

tr|T1G420|T1G420_HELRO
Uncharacterized protein
Search

tr|T1G421|T1G421_HELRO
Uncharacterized protein
Search

DLST

0.46	Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex

0.70	GO:0006099	tricarboxylic acid cycle
0.47	GO:0018335	protein succinylation
0.40	GO:0070584	mitochondrion morphogenesis
0.40	GO:0060047	heart contraction
0.39	GO:0048731	system development
0.37	GO:2000647	negative regulation of stem cell proliferation
0.37	GO:2000178	negative regulation of neural precursor cell proliferation
0.37	GO:0002376	immune system process
0.37	GO:0006754	ATP biosynthetic process
0.37	GO:0051961	negative regulation of nervous system development

0.81	GO:0016751	S-succinyltransferase activity
0.58	GO:0140096	catalytic activity, acting on a protein

0.80	GO:0045252	oxoglutarate dehydrogenase complex
0.42	GO:0043209	myelin sheath
0.39	GO:0005739	mitochondrion
0.38	GO:0005634	nucleus
0.34	GO:0070062	extracellular exosome
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.81

GO:0016751

tr|T1G422|T1G422_HELRO
Uncharacterized protein
Search

0.65	PDZ and LIM domain protein 5

0.42	GO:0098609	cell-cell adhesion
0.39	GO:0045944	positive regulation of transcription by RNA polymerase II
0.37	GO:0061001	regulation of dendritic spine morphogenesis
0.37	GO:0001952	regulation of cell-matrix adhesion
0.36	GO:0051963	regulation of synapse assembly
0.36	GO:0061049	cell growth involved in cardiac muscle cell development
0.32	GO:0006351	transcription, DNA-templated

0.54	GO:0046872	metal ion binding
0.45	GO:0098641	cadherin binding involved in cell-cell adhesion
0.40	GO:0003713	transcription coactivator activity
0.38	GO:0042805	actinin binding
0.36	GO:0005080	protein kinase C binding
0.35	GO:0047485	protein N-terminus binding
0.34	GO:0003779	actin binding
0.34	GO:0043565	sequence-specific DNA binding
0.34	GO:0030159	receptor signaling complex scaffold activity
0.32	GO:0030246	carbohydrate binding

0.44	GO:0005913	cell-cell adherens junction
0.42	GO:0015629	actin cytoskeleton
0.36	GO:0014069	postsynaptic density
0.36	GO:0045211	postsynaptic membrane
0.36	GO:0043005	neuron projection
0.35	GO:0030018	Z disc
0.35	GO:0005634	nucleus
0.35	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

tr|T1G423|T1G423_HELRO
Uncharacterized protein
Search

ABCG2

0.90	Placenta-specific ATP-binding cassette transporter

0.50	GO:0055085	transmembrane transport
0.49	GO:0046415	urate metabolic process
0.48	GO:0033344	cholesterol efflux
0.43	GO:0015893	drug transport
0.38	GO:0097744	urate salt excretion
0.37	GO:1904612	response to 2,3,7,8-tetrachlorodibenzodioxine
0.37	GO:0019389	glucuronoside metabolic process
0.37	GO:1904479	negative regulation of intestinal absorption
0.37	GO:0060136	embryonic process involved in female pregnancy
0.37	GO:0051593	response to folic acid

0.61	GO:0016887	ATPase activity
0.59	GO:0015399	primary active transmembrane transporter activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0017127	cholesterol transporter activity
0.46	GO:0042803	protein homodimerization activity
0.37	GO:0042910	xenobiotic transmembrane transporter activity
0.37	GO:0015238	drug transmembrane transporter activity
0.35	GO:0008092	cytoskeletal protein binding

0.47	GO:0016324	apical plasma membrane
0.45	GO:0043235	receptor complex
0.42	GO:0005634	nucleus
0.36	GO:0031966	mitochondrial membrane
0.34	GO:0043190	ATP-binding cassette (ABC) transporter complex

0.61

GO:0016887

tr|T1G424|T1G424_HELRO
Uncharacterized protein
Search

0.50	Fibrinogen

0.64	GO:0007596	blood coagulation
0.63	GO:0072376	protein activation cascade
0.62	GO:0001775	cell activation
0.60	GO:0006959	humoral immune response
0.59	GO:0043654	recognition of apoptotic cell
0.59	GO:0051258	protein polymerization
0.58	GO:0048584	positive regulation of response to stimulus
0.55	GO:0050714	positive regulation of protein secretion
0.54	GO:0006952	defense response
0.54	GO:0002684	positive regulation of immune system process

0.61	GO:0030674	protein binding, bridging
0.60	GO:0005102	receptor binding
0.58	GO:0033691	sialic acid binding
0.53	GO:2001065	mannan binding
0.50	GO:0043394	proteoglycan binding
0.50	GO:0048306	calcium-dependent protein binding
0.50	GO:0003823	antigen binding
0.48	GO:0050839	cell adhesion molecule binding
0.47	GO:0038187	pattern recognition receptor activity
0.46	GO:0051087	chaperone binding

0.65	GO:0005577	fibrinogen complex
0.54	GO:0009897	external side of plasma membrane
0.51	GO:0031091	platelet alpha granule
0.47	GO:0005581	collagen trimer
0.46	GO:0005938	cell cortex
0.45	GO:0072562	blood microparticle
0.44	GO:0019897	extrinsic component of plasma membrane
0.44	GO:0005783	endoplasmic reticulum
0.41	GO:1904813	ficolin-1-rich granule lumen
0.41	GO:0070062	extracellular exosome

0.40

GO:0004252

tr|T1G425|T1G425_HELRO
Anoctamin
Search

ANO7

0.66

Anoctamin

0.76	GO:0061588	calcium activated phospholipid scrambling
0.43	GO:1902476	chloride transmembrane transport
0.36	GO:0006869	lipid transport

0.67	GO:0046983	protein dimerization activity
0.47	GO:0017128	phospholipid scramblase activity
0.47	GO:0061778	intracellular chloride channel activity
0.42	GO:0022839	ion gated channel activity
0.42	GO:0008381	mechanosensitive ion channel activity
0.35	GO:0003924	GTPase activity
0.35	GO:0032550	purine ribonucleoside binding
0.35	GO:0019001	guanyl nucleotide binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.42	GO:0005783	endoplasmic reticulum
0.39	GO:0005634	nucleus
0.37	GO:0005886	plasma membrane
0.34	GO:0030054	cell junction
0.33	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

tr|T1G426|T1G426_HELRO
Uncharacterized protein
Search

tr|T1G427|T1G427_HELRO
Uncharacterized protein
Search

0.61	GO:0006030	chitin metabolic process
0.60	GO:0005975	carbohydrate metabolic process
0.46	GO:2000360	negative regulation of binding of sperm to zona pellucida
0.44	GO:1901072	glucosamine-containing compound catabolic process
0.42	GO:0006026	aminoglycan catabolic process
0.41	GO:0042737	drug catabolic process
0.39	GO:0007338	single fertilization
0.37	GO:0018990	ecdysis, chitin-based cuticle
0.35	GO:0009988	cell-cell recognition
0.34	GO:0007565	female pregnancy

0.77	GO:0008061	chitin binding
0.62	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.34	GO:0030246	carbohydrate binding

0.55	GO:0005576	extracellular region
0.45	GO:0035805	egg coat
0.38	GO:0030133	transport vesicle
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.62

GO:0004553

tr|T1G428|T1G428_HELRO
Uncharacterized protein
Search

0.10	p65 transcription factor (Fragment)

0.75	GO:0006366	transcription by RNA polymerase II
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0070884	regulation of calcineurin-NFAT signaling cascade
0.51	GO:0001816	cytokine production
0.47	GO:1902680	positive regulation of RNA biosynthetic process
0.42	GO:0007507	heart development
0.35	GO:0006970	response to osmotic stress
0.34	GO:0032958	inositol phosphate biosynthetic process

0.79	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.34	GO:0020037	heme binding
0.33	GO:0016491	oxidoreductase activity
0.33	GO:0046872	metal ion binding
0.33	GO:0016301	kinase activity

0.46	GO:0005654	nucleoplasm
0.45	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.33

GO:0016491

tr|T1G429|T1G429_HELRO
Uncharacterized protein
Search

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.42	GO:0098916	anterograde trans-synaptic signaling
0.41	GO:0007631	feeding behavior

0.72	GO:0004930	G-protein coupled receptor activity
0.62	GO:0016500	protein-hormone receptor activity
0.39	GO:0001653	peptide receptor activity
0.39	GO:0042923	neuropeptide binding

0.37	GO:0043005	neuron projection
0.36	GO:0005887	integral component of plasma membrane

tr|T1G430|T1G430_HELRO
Uncharacterized protein
Search

ATOX1

0.58	Antioxidant 1 copper chaperone

0.66	GO:0030001	metal ion transport
0.47	GO:0006878	cellular copper ion homeostasis
0.40	GO:0006979	response to oxidative stress
0.40	GO:0046907	intracellular transport

0.54	GO:0046872	metal ion binding
0.50	GO:0032767	copper-dependent protein binding
0.49	GO:0016530	metallochaperone activity

0.35	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|T1G431|T1G431_HELRO
Uncharacterized protein
Search

ACSF2

0.39	AMP-dependent synthetase and ligase

0.39	GO:0006631	fatty acid metabolic process
0.35	GO:0006637	acyl-CoA metabolic process
0.33	GO:0055114	oxidation-reduction process

0.40	GO:0016874	ligase activity
0.36	GO:0030554	adenyl nucleotide binding
0.36	GO:0097367	carbohydrate derivative binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0008942	nitrite reductase [NAD(P)H] activity
0.34	GO:0005515	protein binding

0.45	GO:0005739	mitochondrion
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part

0.40	EC:6	GO:0016874
0.35	KEGG:R00787 KEGG:R00789	GO:0008942

tr|T1G432|T1G432_HELRO
Uncharacterized protein
Search

0.69	GO:0070588	calcium ion transmembrane transport
0.61	GO:0034765	regulation of ion transmembrane transport
0.40	GO:0019228	neuronal action potential
0.40	GO:0086010	membrane depolarization during action potential
0.38	GO:0035725	sodium ion transmembrane transport
0.37	GO:0070509	calcium ion import
0.37	GO:0030488	tRNA methylation
0.33	GO:0006508	proteolysis

0.73	GO:0005245	voltage-gated calcium channel activity
0.39	GO:0016428	tRNA (cytosine-5-)-methyltransferase activity
0.39	GO:0005248	voltage-gated sodium channel activity
0.35	GO:0003723	RNA binding
0.33	GO:0070001	aspartic-type peptidase activity
0.33	GO:0004175	endopeptidase activity
0.33	GO:0008270	zinc ion binding

0.72	GO:0005891	voltage-gated calcium channel complex
0.33	GO:0005887	integral component of plasma membrane

0.39

GO:0016428

tr|T1G433|T1G433_HELRO
Uncharacterized protein
Search

0.10	Peroxisomal targeting signal 1 receptor

0.78	GO:0016558	protein import into peroxisome matrix
0.77	GO:0021895	cerebral cortex neuron differentiation
0.75	GO:0021795	cerebral cortex cell migration
0.75	GO:0040018	positive regulation of multicellular organism growth
0.73	GO:0050905	neuromuscular process
0.73	GO:0000038	very long-chain fatty acid metabolic process
0.73	GO:0001764	neuron migration
0.72	GO:0007029	endoplasmic reticulum organization
0.70	GO:0007006	mitochondrial membrane organization
0.67	GO:0006635	fatty acid beta-oxidation

0.71	GO:0005052	peroxisome matrix targeting signal-1 binding
0.49	GO:0008022	protein C-terminus binding
0.45	GO:0047485	protein N-terminus binding
0.43	GO:0031267	small GTPase binding
0.37	GO:0005509	calcium ion binding

0.68	GO:0005829	cytosol
0.66	GO:0005794	Golgi apparatus
0.62	GO:0031903	microbody membrane
0.62	GO:0044439	peroxisomal part
0.54	GO:0005739	mitochondrion
0.52	GO:0031907	microbody lumen
0.38	GO:0043234	protein complex

tr|T1G434|T1G434_HELRO
Uncharacterized protein
Search

tr|T1G435|T1G435_HELRO
Uncharacterized protein
Search

0.51	Neuronal calcium sensor

0.50	GO:0019722	calcium-mediated signaling
0.49	GO:0003073	regulation of systemic arterial blood pressure
0.39	GO:1905949	negative regulation of calcium ion import across plasma membrane
0.37	GO:0048583	regulation of response to stimulus
0.37	GO:0042327	positive regulation of phosphorylation
0.37	GO:0043085	positive regulation of catalytic activity
0.36	GO:0030516	regulation of axon extension
0.36	GO:0010646	regulation of cell communication
0.36	GO:0023051	regulation of signaling
0.36	GO:0051270	regulation of cellular component movement

0.70	GO:0005509	calcium ion binding
0.48	GO:0030276	clathrin binding
0.46	GO:0015631	tubulin binding
0.46	GO:0003779	actin binding
0.40	GO:0098744	1-phosphatidylinositol 4-kinase activator activity
0.34	GO:0016174	NAD(P)H oxidase activity
0.33	GO:0015276	ligand-gated ion channel activity

0.37	GO:0044431	Golgi apparatus part
0.37	GO:0098588	bounding membrane of organelle
0.36	GO:0031984	organelle subcompartment
0.35	GO:0005829	cytosol
0.35	GO:0070062	extracellular exosome
0.34	GO:0005886	plasma membrane
0.34	GO:0030140	trans-Golgi network transport vesicle
0.33	GO:0030118	clathrin coat
0.33	GO:0030659	cytoplasmic vesicle membrane
0.33	GO:0098805	whole membrane

0.34

EC:1.6.3.1

GO:0016174

tr|T1G436|T1G436_HELRO
Uncharacterized protein
Search

0.79	TFIIH basal transcription factor complex TTD-A subunit

0.73	GO:0006289	nucleotide-excision repair
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0006366	transcription by RNA polymerase II
0.46	GO:0009411	response to UV
0.46	GO:0006468	protein phosphorylation
0.39	GO:0006362	transcription elongation from RNA polymerase I promoter
0.38	GO:0071480	cellular response to gamma radiation
0.38	GO:0071824	protein-DNA complex subunit organization

0.38	GO:0000182	rDNA binding
0.34	GO:0000990	transcription factor activity, core RNA polymerase binding
0.34	GO:0070840	dynein complex binding
0.33	GO:0046872	metal ion binding

0.81	GO:0000439	core TFIIH complex
0.59	GO:0005675	holo TFIIH complex
0.48	GO:0005829	cytosol
0.37	GO:0005669	transcription factor TFIID complex
0.36	GO:0005730	nucleolus
0.34	GO:0000922	spindle pole
0.34	GO:0005875	microtubule associated complex
0.33	GO:0005874	microtubule
0.30	GO:0016021	integral component of membrane

tr|T1G437|T1G437_HELRO
Uncharacterized protein
Search

0.11	Pikachurin (Fragment)

0.43	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.42	GO:0007219	Notch signaling pathway
0.41	GO:0032501	multicellular organismal process
0.39	GO:0001667	ameboidal-type cell migration
0.39	GO:0048856	anatomical structure development
0.35	GO:0030154	cell differentiation
0.35	GO:0007160	cell-matrix adhesion
0.33	GO:0050482	arachidonic acid secretion
0.33	GO:0050793	regulation of developmental process
0.32	GO:0006644	phospholipid metabolic process

0.69	GO:0005509	calcium ion binding
0.42	GO:0005112	Notch binding
0.33	GO:0004623	phospholipase A2 activity
0.32	GO:0004872	receptor activity
0.32	GO:0016301	kinase activity

0.39	GO:0005913	cell-cell adherens junction
0.37	GO:0005886	plasma membrane
0.33	GO:0005581	collagen trimer
0.32	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.33

EC:3.1.1.4

GO:0004623

tr|T1G438|T1G438_HELRO
Uncharacterized protein
Search

0.57	Fibrinogen

0.56	GO:0002752	cell surface pattern recognition receptor signaling pathway
0.55	GO:0043654	recognition of apoptotic cell
0.54	GO:2000484	positive regulation of interleukin-8 secretion
0.54	GO:0046597	negative regulation of viral entry into host cell
0.53	GO:0034394	protein localization to cell surface
0.49	GO:0045087	innate immune response
0.46	GO:0007186	G-protein coupled receptor signaling pathway
0.43	GO:0007219	Notch signaling pathway
0.40	GO:0030154	cell differentiation
0.40	GO:0050793	regulation of developmental process

0.60	GO:0033691	sialic acid binding
0.52	GO:0008329	signaling pattern recognition receptor activity
0.50	GO:0001664	G-protein coupled receptor binding
0.46	GO:0005509	calcium ion binding
0.46	GO:0030246	carbohydrate binding
0.40	GO:0051015	actin filament binding
0.37	GO:0005198	structural molecule activity

0.54	GO:0031232	extrinsic component of external side of plasma membrane
0.49	GO:0005581	collagen trimer
0.45	GO:0005576	extracellular region
0.39	GO:0015629	actin cytoskeleton
0.30	GO:0016021	integral component of membrane

tr|T1G439|T1G439_HELRO
Uncharacterized protein
Search

0.10	Anoctamin-1 (Fragment)

0.48

GO:0016310

phosphorylation

0.54	GO:0046983	protein dimerization activity
0.50	GO:0016301	kinase activity

tr|T1G440|T1G440_HELRO
Bestrophin homolog
Search

0.66	Bestrophin

0.74	GO:1902476	chloride transmembrane transport
0.57	GO:0007601	visual perception
0.47	GO:0030321	transepithelial chloride transport
0.47	GO:0050962	detection of light stimulus involved in sensory perception
0.45	GO:0009992	cellular water homeostasis
0.45	GO:0051924	regulation of calcium ion transport
0.45	GO:0009584	detection of visible light
0.39	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay
0.39	GO:0070481	nuclear-transcribed mRNA catabolic process, non-stop decay
0.39	GO:0071025	RNA surveillance

0.74	GO:0005254	chloride channel activity
0.45	GO:0005225	volume-sensitive anion channel activity
0.42	GO:0042802	identical protein binding
0.41	GO:0022839	ion gated channel activity
0.41	GO:0008381	mechanosensitive ion channel activity
0.34	GO:0015106	bicarbonate transmembrane transporter activity

0.77	GO:0034707	chloride channel complex
0.53	GO:0005886	plasma membrane
0.34	GO:0005929	cilium
0.33	GO:0005829	cytosol

tr|T1G441|T1G441_HELRO
Uncharacterized protein
Search

tr|T1G442|T1G442_HELRO
Uncharacterized protein
Search

0.53	Protein phosphatase 1 regulatory subunit 16A

0.78	GO:0043666	regulation of phosphoprotein phosphatase activity
0.71	GO:1902309	negative regulation of peptidyl-serine dephosphorylation
0.70	GO:1903589	positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis
0.68	GO:0061028	establishment of endothelial barrier
0.66	GO:0035307	positive regulation of protein dephosphorylation
0.66	GO:0014066	regulation of phosphatidylinositol 3-kinase signaling
0.43	GO:0051489	regulation of filopodium assembly
0.42	GO:0007476	imaginal disc-derived wing morphogenesis
0.33	GO:0055114	oxidation-reduction process

0.79	GO:0019888	protein phosphatase regulator activity
0.43	GO:0008157	protein phosphatase 1 binding
0.36	GO:0008113	peptide-methionine (S)-S-oxide reductase activity

0.62	GO:0016607	nuclear speck
0.62	GO:0048471	perinuclear region of cytoplasm
0.55	GO:0042995	cell projection
0.46	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.36

EC:1.8.4 EC:1.8.4.11

GO:0008113

tr|T1G443|T1G443_HELRO
Uncharacterized protein
Search

0.70	Apoptosis regulator BCL-W

0.84	GO:1904247	positive regulation of polynucleotide adenylyltransferase activity
0.43	GO:0042981	regulation of apoptotic process
0.43	GO:0071222	cellular response to lipopolysaccharide
0.42	GO:0006915	apoptotic process
0.42	GO:0000165	MAPK cascade
0.42	GO:0016973	poly(A)+ mRNA export from nucleus
0.40	GO:0043069	negative regulation of programmed cell death
0.38	GO:0031124	mRNA 3'-end processing
0.38	GO:0043631	RNA polyadenylation
0.36	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules

0.59	GO:0003723	RNA binding
0.41	GO:0070063	RNA polymerase binding
0.41	GO:0097718	disordered domain specific binding
0.39	GO:0046982	protein heterodimerization activity
0.39	GO:0042802	identical protein binding
0.36	GO:0043621	protein self-association
0.35	GO:0005509	calcium ion binding
0.33	GO:0003735	structural constituent of ribosome

0.44	GO:0042405	nuclear inclusion body
0.42	GO:0097136	Bcl-2 family protein complex
0.39	GO:0016604	nuclear body
0.39	GO:0030529	intracellular ribonucleoprotein complex
0.37	GO:0000790	nuclear chromatin
0.37	GO:0005730	nucleolus
0.35	GO:0005737	cytoplasm
0.35	GO:0031968	organelle outer membrane
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1G444|T1G444_HELRO
Uncharacterized protein
Search

0.53	GO:0055114	oxidation-reduction process
0.43	GO:0019369	arachidonic acid metabolic process
0.36	GO:0007548	sex differentiation
0.36	GO:0006694	steroid biosynthetic process
0.35	GO:0043651	linoleic acid metabolic process
0.35	GO:0033574	response to testosterone

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.66	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.38	GO:0047442	17-alpha-hydroxyprogesterone aldolase activity
0.36	GO:0019825	oxygen binding

0.34	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

tr|T1G445|T1G445_HELRO
Uncharacterized protein
Search

0.73	T-box transcription factor mls-1

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.44	GO:0042694	muscle cell fate specification
0.42	GO:0043282	pharyngeal muscle development
0.41	GO:0009791	post-embryonic development
0.41	GO:0042048	olfactory behavior
0.38	GO:0032880	regulation of protein localization
0.37	GO:0040011	locomotion

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.38	GO:0019899	enzyme binding
0.34	GO:0001067	regulatory region nucleic acid binding
0.33	GO:0098772	molecular function regulator

0.61	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm
0.33	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

tr|T1G446|T1G446_HELRO
Uncharacterized protein
Search

SKOR2

0.77	SKI family transcriptional corepressor 2

0.81	GO:0090101	negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
0.81	GO:0090288	negative regulation of cellular response to growth factor stimulus
0.73	GO:0030510	regulation of BMP signaling pathway
0.69	GO:1903507	negative regulation of nucleic acid-templated transcription
0.66	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway
0.50	GO:0030182	neuron differentiation
0.49	GO:0045595	regulation of cell differentiation
0.49	GO:0048468	cell development
0.47	GO:0051093	negative regulation of developmental process
0.47	GO:0021936	regulation of cerebellar granule cell precursor proliferation

0.85	GO:0046332	SMAD binding
0.78	GO:0003714	transcription corepressor activity
0.45	GO:0042826	histone deacetylase binding
0.43	GO:0003682	chromatin binding
0.35	GO:0003677	DNA binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.51	GO:0005634	nucleus
0.46	GO:0043025	neuronal cell body
0.45	GO:0030425	dendrite
0.44	GO:0005667	transcription factor complex
0.42	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1G447|T1G447_HELRO
Uncharacterized protein
Search

0.76	Fork head transcription factor (Fragment)

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.43	GO:0030154	cell differentiation
0.43	GO:0009653	anatomical structure morphogenesis
0.42	GO:0043584	nose development
0.41	GO:0060041	retina development in camera-type eye
0.40	GO:0009790	embryo development
0.39	GO:0007399	nervous system development
0.38	GO:0006351	transcription, DNA-templated

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.34	GO:0003779	actin binding

0.61	GO:0005634	nucleus
0.34	GO:0042025	host cell nucleus
0.30	GO:0016020	membrane

tr|T1G448|T1G448_HELRO
Uncharacterized protein
Search

0.54	Fibrinogen C domain-containing protein 1

0.53	GO:0002752	cell surface pattern recognition receptor signaling pathway
0.52	GO:0043654	recognition of apoptotic cell
0.51	GO:2000484	positive regulation of interleukin-8 secretion
0.51	GO:0046597	negative regulation of viral entry into host cell
0.50	GO:0034394	protein localization to cell surface
0.44	GO:0007186	G-protein coupled receptor signaling pathway
0.44	GO:0045087	innate immune response
0.41	GO:0030199	collagen fibril organization
0.41	GO:0006956	complement activation
0.38	GO:0007155	cell adhesion

0.55	GO:0033691	sialic acid binding
0.51	GO:0008061	chitin binding
0.50	GO:0008329	signaling pattern recognition receptor activity
0.48	GO:0001664	G-protein coupled receptor binding
0.43	GO:0030246	carbohydrate binding
0.40	GO:0046872	metal ion binding
0.35	GO:0051015	actin filament binding
0.34	GO:0005198	structural molecule activity

0.52	GO:0031232	extrinsic component of external side of plasma membrane
0.44	GO:0005581	collagen trimer
0.43	GO:0005576	extracellular region
0.35	GO:0015629	actin cytoskeleton
0.30	GO:0016021	integral component of membrane

tr|T1G449|T1G449_HELRO
Uncharacterized protein
Search

CSTF1

0.94	Cleavage stimulation factor subunit 1

0.45	GO:0006397	mRNA processing
0.41	GO:0006369	termination of RNA polymerase II transcription
0.39	GO:0031123	RNA 3'-end processing
0.39	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
0.36	GO:0006468	protein phosphorylation

0.38	GO:0003723	RNA binding
0.37	GO:0005515	protein binding
0.36	GO:0004672	protein kinase activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.68	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1G450|T1G450_HELRO
Uncharacterized protein
Search

0.10	Low-density lipoprotein receptor-related protein 2 (Fragment)

0.45	GO:0006030	chitin metabolic process
0.44	GO:0007275	multicellular organism development
0.42	GO:0030154	cell differentiation
0.41	GO:0016477	cell migration
0.41	GO:0120036	plasma membrane bounded cell projection organization
0.39	GO:0006897	endocytosis
0.39	GO:0005975	carbohydrate metabolic process
0.39	GO:0006508	proteolysis
0.38	GO:1904252	negative regulation of bile acid metabolic process
0.38	GO:0035150	regulation of tube size

0.55	GO:0005509	calcium ion binding
0.44	GO:0008061	chitin binding
0.41	GO:0004252	serine-type endopeptidase activity
0.41	GO:0004099	chitin deacetylase activity
0.40	GO:0038024	cargo receptor activity
0.37	GO:0004888	transmembrane signaling receptor activity
0.35	GO:0071813	lipoprotein particle binding
0.35	GO:0001540	amyloid-beta binding
0.35	GO:0005515	protein binding
0.35	GO:0004568	chitinase activity

0.42	GO:0005576	extracellular region
0.41	GO:0012505	endomembrane system
0.39	GO:0005887	integral component of plasma membrane
0.39	GO:0031410	cytoplasmic vesicle
0.36	GO:0043231	intracellular membrane-bounded organelle
0.36	GO:0043235	receptor complex
0.36	GO:0098589	membrane region
0.35	GO:0016324	apical plasma membrane
0.34	GO:0019897	extrinsic component of plasma membrane
0.34	GO:0031526	brush border membrane

0.41

GO:0004252

tr|T1G451|T1G451_HELRO
Uncharacterized protein
Search

0.71	Dynein heavy chain 5 axonemal

0.74	GO:0007018	microtubule-based movement
0.55	GO:0007368	determination of left/right symmetry
0.55	GO:0036158	outer dynein arm assembly
0.50	GO:0007507	heart development
0.48	GO:0021670	lateral ventricle development
0.42	GO:0030317	flagellated sperm motility
0.34	GO:0060285	cilium-dependent cell motility

0.75	GO:0003777	microtubule motor activity
0.60	GO:0016887	ATPase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0045503	dynein light chain binding
0.52	GO:0051959	dynein light intermediate chain binding
0.52	GO:0045505	dynein intermediate chain binding

0.79	GO:0030286	dynein complex
0.58	GO:0044447	axoneme part
0.47	GO:0097228	sperm principal piece
0.34	GO:0005874	microtubule
0.30	GO:0031224	intrinsic component of membrane

0.60

GO:0016887

tr|T1G452|T1G452_HELRO
Uncharacterized protein
Search

0.67	GO:0007155	cell adhesion
0.40	GO:0070593	dendrite self-avoidance
0.40	GO:0050976	detection of mechanical stimulus involved in sensory perception of touch
0.40	GO:0021551	central nervous system morphogenesis
0.40	GO:1902284	neuron projection extension involved in neuron projection guidance
0.40	GO:0007419	ventral cord development
0.40	GO:0016319	mushroom body development
0.40	GO:0032490	detection of molecule of bacterial origin
0.40	GO:0007413	axonal fasciculation
0.39	GO:0048675	axon extension

0.40	GO:0005509	calcium ion binding
0.40	GO:0008046	axon guidance receptor activity
0.39	GO:0003823	antigen binding
0.38	GO:0042803	protein homodimerization activity
0.33	GO:0030246	carbohydrate binding
0.33	GO:0004672	protein kinase activity
0.33	GO:0008270	zinc ion binding
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0008144	drug binding

0.38	GO:0043025	neuronal cell body
0.38	GO:0030425	dendrite
0.38	GO:0030424	axon
0.36	GO:0005604	basement membrane
0.36	GO:0005887	integral component of plasma membrane
0.36	GO:0005938	cell cortex
0.36	GO:0030054	cell junction
0.34	GO:0070062	extracellular exosome

tr|T1G453|T1G453_HELRO
Uncharacterized protein
Search

tr|T1G454|T1G454_HELRO
Uncharacterized protein
Search

0.71	GO:0007166	cell surface receptor signaling pathway
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.49	GO:0019933	cAMP-mediated signaling
0.38	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.35	GO:0006913	nucleocytoplasmic transport
0.35	GO:0016525	negative regulation of angiogenesis

0.72	GO:0004930	G-protein coupled receptor activity
0.38	GO:0005509	calcium ion binding
0.34	GO:0003924	GTPase activity
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0019001	guanyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.39	GO:0005886	plasma membrane
0.36	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

tr|T1G455|T1G455_HELRO
Uncharacterized protein
Search

0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.55	GO:0061011	hepatic duct development
0.55	GO:0060431	primary lung bud formation
0.55	GO:0061017	hepatoblast differentiation
0.55	GO:0061010	gall bladder development
0.54	GO:0022027	interkinetic nuclear migration
0.54	GO:0070365	hepatocyte differentiation
0.54	GO:0090009	primitive streak formation

0.64	GO:0043565	sequence-specific DNA binding
0.54	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.53	GO:0071837	HMG box domain binding
0.52	GO:0008190	eukaryotic initiation factor 4E binding
0.52	GO:0001012	RNA polymerase II regulatory region DNA binding
0.52	GO:0008301	DNA binding, bending
0.52	GO:0070491	repressing transcription factor binding
0.49	GO:0003690	double-stranded DNA binding
0.49	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.48	GO:0003682	chromatin binding

0.61	GO:0005634	nucleus
0.46	GO:0032993	protein-DNA complex
0.38	GO:0005737	cytoplasm
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0043232	intracellular non-membrane-bounded organelle

tr|T1G456|T1G456_HELRO
Uncharacterized protein
Search

0.44	GO:0007219	Notch signaling pathway
0.44	GO:0032501	multicellular organismal process
0.42	GO:0032502	developmental process
0.41	GO:0050793	regulation of developmental process
0.41	GO:0007599	hemostasis
0.41	GO:0042060	wound healing
0.40	GO:0045199	maintenance of epithelial cell apical/basal polarity
0.39	GO:0030513	positive regulation of BMP signaling pathway
0.39	GO:0007160	cell-matrix adhesion
0.39	GO:0001667	ameboidal-type cell migration

0.70	GO:0005509	calcium ion binding
0.40	GO:0019828	aspartic-type endopeptidase inhibitor activity
0.39	GO:0005112	Notch binding
0.38	GO:0004252	serine-type endopeptidase activity
0.37	GO:0019899	enzyme binding
0.35	GO:0008429	phosphatidylethanolamine binding
0.35	GO:0001786	phosphatidylserine binding
0.35	GO:0005178	integrin binding
0.35	GO:0004872	receptor activity
0.34	GO:0005201	extracellular matrix structural constituent

0.41	GO:0005576	extracellular region
0.39	GO:0016324	apical plasma membrane
0.35	GO:0043234	protein complex
0.35	GO:0009897	external side of plasma membrane
0.35	GO:0019897	extrinsic component of plasma membrane
0.34	GO:0005912	adherens junction
0.33	GO:0031410	cytoplasmic vesicle
0.30	GO:0016021	integral component of membrane

0.38

GO:0004252

tr|T1G457|T1G457_HELRO
Uncharacterized protein
Search

0.55	Vesicle-associated membrane protein

0.69	GO:0016192	vesicle-mediated transport
0.39	GO:0032259	methylation

0.39

GO:0008168

methyltransferase activity

0.42	GO:0005730	nucleolus
0.30	GO:0016020	membrane

0.39

GO:0008168

tr|T1G458|T1G458_HELRO
Uncharacterized protein
Search

0.67	GATA transcription factor (Fragment)

0.58	GO:0045893	positive regulation of transcription, DNA-templated
0.55	GO:0060575	intestinal epithelial cell differentiation
0.53	GO:0071773	cellular response to BMP stimulus
0.50	GO:0007493	endodermal cell fate determination
0.49	GO:0060486	Clara cell differentiation
0.49	GO:0032912	negative regulation of transforming growth factor beta2 production
0.49	GO:0060510	Type II pneumocyte differentiation
0.49	GO:0051891	positive regulation of cardioblast differentiation
0.49	GO:0110024	positive regulation of cardiac muscle myoblast proliferation
0.49	GO:0060430	lung saccule development

0.65	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.52	GO:0044212	transcription regulatory region DNA binding
0.51	GO:0001085	RNA polymerase II transcription factor binding
0.50	GO:0003690	double-stranded DNA binding
0.49	GO:0003682	chromatin binding
0.47	GO:0070491	repressing transcription factor binding
0.44	GO:0019901	protein kinase binding
0.33	GO:0005096	GTPase activator activity

0.51	GO:0005634	nucleus
0.48	GO:0005667	transcription factor complex
0.41	GO:0012505	endomembrane system
0.39	GO:0031967	organelle envelope
0.39	GO:0031090	organelle membrane
0.34	GO:0070013	intracellular organelle lumen
0.30	GO:0016021	integral component of membrane

tr|T1G459|T1G459_HELRO
Uncharacterized protein
Search

tr|T1G460|T1G460_HELRO
Uncharacterized protein
Search

0.57	Ficolin (Collagen/fibrinogen domain containing) 3 (Hakata antigen)

0.67	GO:0007596	blood coagulation
0.53	GO:0001525	angiogenesis
0.50	GO:0001775	cell activation
0.50	GO:0043623	cellular protein complex assembly
0.47	GO:0043537	negative regulation of blood vessel endothelial cell migration
0.46	GO:0016525	negative regulation of angiogenesis
0.45	GO:0007165	signal transduction
0.45	GO:0043536	positive regulation of blood vessel endothelial cell migration
0.44	GO:0071456	cellular response to hypoxia
0.44	GO:0043066	negative regulation of apoptotic process

0.55	GO:0005102	receptor binding
0.55	GO:1990782	protein tyrosine kinase binding
0.50	GO:0030674	protein binding, bridging
0.46	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity
0.38	GO:0003823	antigen binding
0.37	GO:0050839	cell adhesion molecule binding
0.35	GO:0008233	peptidase activity
0.35	GO:0005198	structural molecule activity
0.34	GO:0030246	carbohydrate binding
0.32	GO:0046872	metal ion binding

0.57	GO:0005615	extracellular space
0.43	GO:0043234	protein complex
0.38	GO:0031091	platelet alpha granule
0.37	GO:0009897	external side of plasma membrane
0.37	GO:0005938	cell cortex
0.30	GO:0016021	integral component of membrane

0.35

GO:0008233

tr|T1G461|T1G461_HELRO
Uncharacterized protein
Search

tr|T1G462|T1G462_HELRO
Uncharacterized protein
Search

0.59	Fibrinogen

0.63	GO:0002752	cell surface pattern recognition receptor signaling pathway
0.61	GO:0043654	recognition of apoptotic cell
0.60	GO:2000484	positive regulation of interleukin-8 secretion
0.60	GO:0046597	negative regulation of viral entry into host cell
0.59	GO:0034394	protein localization to cell surface
0.54	GO:0030199	collagen fibril organization
0.51	GO:0007186	G-protein coupled receptor signaling pathway
0.47	GO:0001867	complement activation, lectin pathway
0.37	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.36	GO:0006508	proteolysis

0.66	GO:0033691	sialic acid binding
0.59	GO:0008329	signaling pattern recognition receptor activity
0.55	GO:0001664	G-protein coupled receptor binding
0.44	GO:0030246	carbohydrate binding
0.43	GO:0005509	calcium ion binding
0.38	GO:0004222	metalloendopeptidase activity
0.36	GO:0008270	zinc ion binding

0.61	GO:0031232	extrinsic component of external side of plasma membrane
0.50	GO:0005576	extracellular region
0.47	GO:0005581	collagen trimer
0.30	GO:0016021	integral component of membrane

0.38

GO:0004222

tr|T1G463|T1G463_HELRO
Uncharacterized protein
Search

0.68	Splicing factor, suppressor of white-apricot homolog

0.63	GO:0006396	RNA processing
0.47	GO:0022618	ribonucleoprotein complex assembly
0.45	GO:0016071	mRNA metabolic process
0.38	GO:0019310	inositol catabolic process
0.38	GO:0048025	negative regulation of mRNA splicing, via spliceosome
0.34	GO:0055114	oxidation-reduction process
0.34	GO:0006351	transcription, DNA-templated
0.34	GO:0006355	regulation of transcription, DNA-templated
0.33	GO:0006508	proteolysis

0.59	GO:0003723	RNA binding
0.39	GO:0050113	inositol oxygenase activity
0.36	GO:0046914	transition metal ion binding
0.34	GO:0004222	metalloendopeptidase activity
0.34	GO:0005515	protein binding

0.35	GO:0031012	extracellular matrix
0.34	GO:0005634	nucleus
0.33	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.39	EC:1.13.99.1	GO:0050113
0.39	KEGG:R01184	GO:0050113

tr|T1G464|T1G464_HELRO
Uncharacterized protein
Search

0.59	Heat shock protein 12A

0.43

GO:0006508

proteolysis

0.48	GO:0030554	adenyl nucleotide binding
0.48	GO:0097367	carbohydrate derivative binding
0.48	GO:0008144	drug binding
0.48	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0070001	aspartic-type peptidase activity
0.45	GO:0004175	endopeptidase activity
0.42	GO:0005515	protein binding

0.30

GO:0031224

intrinsic component of membrane

tr|T1G465|T1G465_HELRO
Uncharacterized protein
Search

0.57	Serine protease inhibitor serpin

0.55	GO:0010951	negative regulation of endopeptidase activity
0.47	GO:0006508	proteolysis
0.43	GO:2000266	regulation of blood coagulation, intrinsic pathway
0.38	GO:0071391	cellular response to estrogen stimulus
0.36	GO:0009617	response to bacterium
0.36	GO:0032504	multicellular organism reproduction
0.35	GO:0098542	defense response to other organism
0.35	GO:0098609	cell-cell adhesion
0.35	GO:0042270	protection from natural killer cell mediated cytotoxicity
0.34	GO:0002448	mast cell mediated immunity

0.56	GO:0004867	serine-type endopeptidase inhibitor activity
0.48	GO:0008233	peptidase activity
0.42	GO:0008201	heparin binding
0.34	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.34	GO:0002020	protease binding
0.33	GO:0005509	calcium ion binding
0.33	GO:0005102	receptor binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0003677	DNA binding
0.32	GO:0008144	drug binding

0.73	GO:0005615	extracellular space
0.35	GO:0005829	cytosol
0.34	GO:0031232	extrinsic component of external side of plasma membrane
0.34	GO:0031091	platelet alpha granule
0.34	GO:0031594	neuromuscular junction
0.33	GO:0005794	Golgi apparatus
0.33	GO:0005654	nucleoplasm
0.33	GO:0031012	extracellular matrix
0.30	GO:0016021	integral component of membrane

0.48

GO:0008233

tr|T1G466|T1G466_HELRO
Uncharacterized protein
Search

0.39	Potassium voltage-gated channel subfamily H member 7

0.73	GO:0034765	regulation of ion transmembrane transport
0.73	GO:0071805	potassium ion transmembrane transport
0.43	GO:0042391	regulation of membrane potential
0.40	GO:0007605	sensory perception of sound
0.39	GO:0007018	microtubule-based movement
0.37	GO:0023014	signal transduction by protein phosphorylation
0.37	GO:0000160	phosphorelay signal transduction system
0.36	GO:0044837	actomyosin contractile ring organization
0.36	GO:0000912	assembly of actomyosin apparatus involved in cytokinesis
0.36	GO:0099518	vesicle cytoskeletal trafficking

0.78	GO:0005249	voltage-gated potassium channel activity
0.39	GO:0015276	ligand-gated ion channel activity
0.39	GO:0003777	microtubule motor activity
0.39	GO:0008017	microtubule binding
0.37	GO:0000155	phosphorelay sensor kinase activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0003779	actin binding
0.33	GO:0003755	peptidyl-prolyl cis-trans isomerase activity

0.40	GO:0005887	integral component of plasma membrane
0.34	GO:0005622	intracellular
0.34	GO:0034705	potassium channel complex
0.33	GO:0044815	DNA packaging complex
0.33	GO:0043228	non-membrane-bounded organelle
0.33	GO:0032993	protein-DNA complex
0.33	GO:0044422	organelle part
0.32	GO:0043234	protein complex

0.37

EC:2.7.3

GO:0000155

tr|T1G467|T1G467_HELRO
Uncharacterized protein
Search

0.94	Theromacin

0.72

GO:0006952

defense response

0.66

GO:0005576

extracellular region

tr|T1G468|T1G468_HELRO
Uncharacterized protein
Search

0.53	GO:0055114	oxidation-reduction process
0.41	GO:0019369	arachidonic acid metabolic process
0.37	GO:0030476	ascospore wall assembly
0.36	GO:0043651	linoleic acid metabolic process
0.35	GO:0006413	translational initiation
0.35	GO:0019748	secondary metabolic process
0.34	GO:1901376	organic heteropentacyclic compound metabolic process
0.33	GO:0006805	xenobiotic metabolic process
0.33	GO:0018904	ether metabolic process
0.33	GO:0042180	cellular ketone metabolic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.65	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.35	GO:0003743	translation initiation factor activity
0.33	GO:0019825	oxygen binding

0.34	GO:0005788	endoplasmic reticulum lumen
0.33	GO:0009986	cell surface
0.30	GO:0016020	membrane

0.68

GO:0016705

tr|T1G469|T1G469_HELRO
Uncharacterized protein
Search

RUFY2

0.85	RUN and FYVE domain-containing protein 2

0.39	GO:0030433	ubiquitin-dependent ERAD pathway
0.38	GO:0030335	positive regulation of cell migration
0.36	GO:0055085	transmembrane transport
0.35	GO:0030100	regulation of endocytosis
0.34	GO:0006886	intracellular protein transport
0.32	GO:0016310	phosphorylation

0.53	GO:0046872	metal ion binding
0.52	GO:0017124	SH3 domain binding
0.39	GO:0031625	ubiquitin protein ligase binding
0.34	GO:0004386	helicase activity
0.32	GO:0016301	kinase activity

0.39	GO:0005737	cytoplasm
0.39	GO:0071437	invadopodium
0.37	GO:0012505	endomembrane system
0.36	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0097708	intracellular vesicle
0.30	GO:0016020	membrane

tr|T1G470|T1G470_HELRO
Uncharacterized protein
Search

ROPN1L

0.96	cAMP dependent protein kinase regulatory

0.67	GO:0007286	spermatid development
0.61	GO:0030317	flagellated sperm motility
0.60	GO:0048469	cell maturation
0.57	GO:0061512	protein localization to cilium
0.54	GO:0001932	regulation of protein phosphorylation
0.53	GO:0044782	cilium organization
0.44	GO:0003341	cilium movement
0.38	GO:0016310	phosphorylation
0.34	GO:0036211	protein modification process
0.34	GO:0044267	cellular protein metabolic process

0.39	GO:0016301	kinase activity
0.37	GO:0005515	protein binding
0.35	GO:0060089	molecular transducer activity
0.35	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.34	GO:0140096	catalytic activity, acting on a protein

0.70	GO:0031514	motile cilium
0.59	GO:0097598	sperm cytoplasmic droplet
0.52	GO:0044441	ciliary part
0.45	GO:0005737	cytoplasm
0.34	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.35

GO:0016773

tr|T1G471|T1G471_HELRO
Uncharacterized protein
Search

MAP2K1

0.83	Dual specificity mitogen-activated protein kinase kinase 1

0.63	GO:0006468	protein phosphorylation
0.52	GO:0070372	regulation of ERK1 and ERK2 cascade
0.51	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA
0.51	GO:0060502	epithelial cell proliferation involved in lung morphogenesis
0.50	GO:0090398	cellular senescence
0.50	GO:0060440	trachea formation
0.50	GO:0032147	activation of protein kinase activity
0.50	GO:0060020	Bergmann glial cell differentiation
0.49	GO:0030855	epithelial cell differentiation
0.49	GO:0051726	regulation of cell cycle

0.68	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0004728	signal transducer, downstream of receptor, with protein tyrosine phosphatase activity
0.51	GO:0004708	MAP kinase kinase activity
0.50	GO:0097110	scaffold protein binding
0.49	GO:0047485	protein N-terminus binding
0.49	GO:0043539	protein serine/threonine kinase activator activity

0.45	GO:0012505	endomembrane system
0.44	GO:0005829	cytosol
0.41	GO:0043231	intracellular membrane-bounded organelle
0.40	GO:0000793	condensed chromosome
0.39	GO:0005886	plasma membrane
0.38	GO:0005815	microtubule organizing center
0.37	GO:0031967	organelle envelope
0.37	GO:0005925	focal adhesion
0.35	GO:0031410	cytoplasmic vesicle
0.35	GO:0070062	extracellular exosome

0.68

GO:0004674

tr|T1G472|T1G472_HELRO
Uncharacterized protein
Search

0.43	GO:1903241	U2-type prespliceosome assembly
0.37	GO:0010501	RNA secondary structure unwinding
0.34	GO:1990120	messenger ribonucleoprotein complex assembly
0.34	GO:0071047	polyadenylation-dependent mRNA catabolic process
0.33	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.33	GO:0001522	pseudouridine synthesis
0.33	GO:0006364	rRNA processing

0.64	GO:0004386	helicase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0003676	nucleic acid binding
0.43	GO:1990447	U2 snRNP binding
0.43	GO:1990446	U1 snRNP binding
0.38	GO:0016887	ATPase activity
0.35	GO:0140098	catalytic activity, acting on RNA
0.33	GO:0009982	pseudouridine synthase activity

0.41	GO:0071004	U2-type prespliceosome
0.36	GO:0005730	nucleolus
0.33	GO:0005737	cytoplasm

0.38

GO:0016887

tr|T1G473|T1G473_HELRO
Uncharacterized protein
Search

0.61	GO:0034154	toll-like receptor 7 signaling pathway
0.59	GO:0002755	MyD88-dependent toll-like receptor signaling pathway
0.57	GO:0045087	innate immune response
0.55	GO:0051607	defense response to virus
0.44	GO:0016310	phosphorylation
0.43	GO:0036211	protein modification process
0.41	GO:0001817	regulation of cytokine production
0.41	GO:0044267	cellular protein metabolic process
0.40	GO:0051223	regulation of protein transport
0.40	GO:0042116	macrophage activation

0.56	GO:0003727	single-stranded RNA binding
0.51	GO:0004888	transmembrane signaling receptor activity
0.51	GO:0043531	ADP binding
0.45	GO:0016301	kinase activity
0.42	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.41	GO:0140096	catalytic activity, acting on a protein
0.40	GO:0035197	siRNA binding
0.40	GO:0008144	drug binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0003725	double-stranded RNA binding

0.40	GO:0032009	early phagosome
0.39	GO:0043235	receptor complex
0.38	GO:0005764	lysosome
0.38	GO:0005768	endosome
0.38	GO:0005783	endoplasmic reticulum
0.35	GO:0098805	whole membrane
0.35	GO:0005794	Golgi apparatus
0.35	GO:0005886	plasma membrane
0.34	GO:0005576	extracellular region
0.34	GO:0044437	vacuolar part

0.42	EC:2.7.1	GO:0016773
0.34	KEGG:R03532	GO:0004601

tr|T1G474|T1G474_HELRO
Uncharacterized protein
Search

0.54	Adhesion G protein-coupled receptor D1 (Fragment)

0.71	GO:0007166	cell surface receptor signaling pathway
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.52	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.47	GO:0019933	cAMP-mediated signaling
0.46	GO:0036515	serotonergic neuron axon guidance
0.46	GO:0036514	dopaminergic neuron axon guidance
0.45	GO:0090175	regulation of establishment of planar polarity
0.45	GO:0001764	neuron migration
0.44	GO:0007413	axonal fasciculation
0.43	GO:0198738	cell-cell signaling by wnt

0.72	GO:0004930	G-protein coupled receptor activity
0.49	GO:0005509	calcium ion binding
0.42	GO:0030246	carbohydrate binding
0.37	GO:0015116	sulfate transmembrane transporter activity
0.36	GO:0015291	secondary active transmembrane transporter activity
0.34	GO:0003924	GTPase activity
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0019001	guanyl nucleotide binding
0.33	GO:0016301	kinase activity
0.33	GO:0004175	endopeptidase activity

0.44	GO:0005886	plasma membrane
0.35	GO:0005622	intracellular
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044422	organelle part
0.33	GO:0043227	membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

tr|T1G475|T1G475_HELRO
Uncharacterized protein
Search

0.88	Theromacin

0.72

GO:0006952

defense response

0.66

GO:0005576

extracellular region

tr|T1G476|T1G476_HELRO
Uncharacterized protein
Search

0.73	GO:0008285	negative regulation of cell proliferation
0.71	GO:0016055	Wnt signaling pathway
0.44	GO:0016358	dendrite development
0.43	GO:0007626	locomotory behavior
0.41	GO:0070830	bicellular tight junction assembly
0.40	GO:0000187	activation of MAPK activity
0.39	GO:0006198	cAMP catabolic process
0.39	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.39	GO:0048666	neuron development
0.39	GO:0018108	peptidyl-tyrosine phosphorylation

0.83	GO:0070016	armadillo repeat domain binding
0.81	GO:0030331	estrogen receptor binding
0.80	GO:0051721	protein phosphatase 2A binding
0.69	GO:0032403	protein complex binding
0.46	GO:0005516	calmodulin binding
0.40	GO:0048306	calcium-dependent protein binding
0.39	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.39	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity
0.36	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
0.35	GO:0032559	adenyl ribonucleotide binding

0.75	GO:0005923	bicellular tight junction
0.74	GO:0000159	protein phosphatase type 2A complex
0.47	GO:0043197	dendritic spine
0.44	GO:0014069	postsynaptic density
0.43	GO:0043025	neuronal cell body
0.43	GO:0045211	postsynaptic membrane
0.36	GO:0005737	cytoplasm
0.36	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.39

GO:0004714

tr|T1G477|T1G477_HELRO
Uncharacterized protein
Search

SPTLC2

0.81	Serine palmitoyltransferase long chain base subunit 2

0.60	GO:0046520	sphingoid biosynthetic process
0.58	GO:0006667	sphinganine metabolic process
0.57	GO:0006686	sphingomyelin biosynthetic process
0.57	GO:1904502	regulation of lipophagy
0.57	GO:0006670	sphingosine metabolic process
0.55	GO:0046513	ceramide biosynthetic process
0.54	GO:0016239	positive regulation of macroautophagy
0.52	GO:0034312	diol biosynthetic process

0.67	GO:0030170	pyridoxal phosphate binding
0.59	GO:0004758	serine C-palmitoyltransferase activity
0.33	GO:0005515	protein binding

0.59	GO:0017059	serine C-palmitoyltransferase complex
0.44	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

0.59	EC:2.3.1.50	GO:0004758
0.59	KEGG:R01281	GO:0004758

tr|T1G478|T1G478_HELRO
Uncharacterized protein
Search

GTF2B

0.59	Transcription initiation factor TFIIB

0.79	GO:0070897	DNA-templated transcriptional preinitiation complex assembly
0.60	GO:0006413	translational initiation
0.57	GO:1904798	positive regulation of core promoter binding
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.52	GO:0050434	positive regulation of viral transcription
0.51	GO:0006367	transcription initiation from RNA polymerase II promoter
0.35	GO:0042795	snRNA transcription by RNA polymerase II
0.34	GO:0097052	L-kynurenine metabolic process

0.80	GO:0017025	TBP-class protein binding
0.61	GO:0003743	translation initiation factor activity
0.56	GO:0046966	thyroid hormone receptor binding
0.55	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding
0.52	GO:0046872	metal ion binding
0.35	GO:0036137	kynurenine aminotransferase activity
0.33	GO:0030170	pyridoxal phosphate binding

0.56	GO:0097550	transcriptional preinitiation complex
0.52	GO:0005669	transcription factor TFIID complex
0.51	GO:0016604	nuclear body
0.30	GO:0016020	membrane

tr|T1G479|T1G479_HELRO
Uncharacterized protein
Search

HSPA4L

0.71	Polo-like kinase 4 (Drosophila)

0.85	GO:0007099	centriole replication
0.70	GO:0046601	positive regulation of centriole replication
0.67	GO:0098535	de novo centriole assembly involved in multi-ciliated epithelial cell differentiation
0.63	GO:0006468	protein phosphorylation
0.62	GO:0060707	trophoblast giant cell differentiation

0.70	GO:0004674	protein serine/threonine kinase activity
0.57	GO:0042802	identical protein binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.83	GO:0005814	centriole
0.67	GO:0098536	deuterosome
0.63	GO:0001741	XY body
0.60	GO:0005813	centrosome
0.57	GO:0005730	nucleolus
0.54	GO:0005829	cytosol

0.70

GO:0004674

tr|T1G480|T1G480_HELRO
Uncharacterized protein
Search

0.34

GO:0019752

carboxylic acid metabolic process

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0004386	helicase activity
0.44	GO:0003677	DNA binding
0.35	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer

0.30

GO:0044425

membrane part

0.35

EC:2.3.3

GO:0046912

tr|T1G481|T1G481_HELRO
Poly [ADP-ribose] polymerase
Search

0.31	Poly [ADP-ribose] polymerase

0.82	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.41	GO:0046872	metal ion binding
0.40	GO:0003723	RNA binding

0.82

EC:2.4.2.30

GO:0003950

tr|T1G482|T1G482_HELRO
PRA1 family protein
Search

tr|T1G483|T1G483_HELRO
Uncharacterized protein
Search

0.57	Zinc finger MYM-type protein 1

0.68	GO:0046983	protein dimerization activity
0.38	GO:0008270	zinc ion binding

tr|T1G484|T1G484_HELRO
V-type proton ATPase proteolipid subunit
Search

0.61	V-type proton ATPase proteolipid subunit

0.75	GO:0015991	ATP hydrolysis coupled proton transport
0.50	GO:0007042	lysosomal lumen acidification
0.48	GO:0030177	positive regulation of Wnt signaling pathway
0.37	GO:0060036	notochord cell vacuolation
0.37	GO:0006623	protein targeting to vacuole
0.37	GO:0001878	response to yeast
0.36	GO:0060059	embryonic retina morphogenesis in camera-type eye
0.36	GO:0006878	cellular copper ion homeostasis
0.36	GO:0006879	cellular iron ion homeostasis
0.36	GO:0016192	vesicle-mediated transport

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.47	GO:0031625	ubiquitin protein ligase binding
0.47	GO:0036442	proton-exporting ATPase activity
0.44	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
0.34	GO:0005245	voltage-gated calcium channel activity
0.34	GO:0015662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism

0.78	GO:0033179	proton-transporting V-type ATPase, V0 domain
0.76	GO:0005774	vacuolar membrane
0.36	GO:0005925	focal adhesion
0.36	GO:0031982	vesicle
0.36	GO:0043230	extracellular organelle
0.35	GO:0005764	lysosome
0.35	GO:0012505	endomembrane system
0.35	GO:0005615	extracellular space
0.35	GO:0033181	plasma membrane proton-transporting V-type ATPase complex
0.35	GO:0045169	fusome

tr|T1G485|T1G485_HELRO
Uncharacterized protein
Search

WASHC5

0.94	WASH complex subunit strumpellin

0.54	GO:0040038	polar body extrusion after meiotic divisions
0.53	GO:0090306	spindle assembly involved in meiosis
0.53	GO:0001556	oocyte maturation
0.49	GO:0016197	endosomal transport
0.37	GO:0048699	generation of neurons
0.37	GO:0015031	protein transport
0.36	GO:0031346	positive regulation of cell projection organization
0.36	GO:0010720	positive regulation of cell development
0.36	GO:0051962	positive regulation of nervous system development
0.36	GO:0120035	regulation of plasma membrane bounded cell projection organization

0.33	GO:0005515	protein binding
0.33	GO:0008270	zinc ion binding

0.79	GO:0071203	WASH complex
0.51	GO:0005769	early endosome
0.46	GO:0005654	nucleoplasm
0.36	GO:0043025	neuronal cell body
0.36	GO:0005783	endoplasmic reticulum
0.36	GO:0043005	neuron projection
0.36	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|T1G486|T1G486_HELRO
Uncharacterized protein
Search

tr|T1G487|T1G487_HELRO
Uncharacterized protein
Search

0.44	Zinc finger MYM-type protein 1

0.37	GO:0006357	regulation of transcription by RNA polymerase II
0.35	GO:0007275	multicellular organism development
0.34	GO:0046080	dUTP metabolic process
0.33	GO:0016310	phosphorylation

0.68	GO:0046983	protein dimerization activity
0.38	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.35	GO:0003677	DNA binding
0.34	GO:0004170	dUTP diphosphatase activity
0.34	GO:0016301	kinase activity
0.33	GO:0008270	zinc ion binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.37	GO:0005654	nucleoplasm
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.34	EC:3.6.1.23	GO:0004170
0.34	KEGG:R02100	GO:0004170

tr|T1G488|T1G488_HELRO
Uncharacterized protein
Search

0.75	GO:0000723	telomere maintenance
0.67	GO:0032392	DNA geometric change
0.62	GO:0006310	DNA recombination
0.62	GO:0006281	DNA repair
0.32	GO:0006468	protein phosphorylation
0.32	GO:0006508	proteolysis

0.67	GO:0003678	DNA helicase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0046983	protein dimerization activity
0.32	GO:0004672	protein kinase activity
0.32	GO:0003676	nucleic acid binding

0.30

GO:0016020

membrane

tr|T1G489|T1G489_HELRO
Uncharacterized protein
Search

LEPROT

0.92	Leptin receptor overlapping transcript

0.49	GO:2000009	negative regulation of protein localization to cell surface
0.49	GO:0060400	negative regulation of growth hormone receptor signaling pathway
0.47	GO:0032511	late endosome to vacuole transport via multivesicular body sorting pathway
0.46	GO:0046426	negative regulation of JAK-STAT cascade
0.37	GO:1903955	positive regulation of protein targeting to mitochondrion
0.33	GO:0015031	protein transport

0.42

GO:0005102

receptor binding

0.45	GO:0005768	endosome
0.40	GO:0044433	cytoplasmic vesicle part
0.39	GO:0098805	whole membrane
0.39	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1G490|T1G490_HELRO
Uncharacterized protein
Search

TOMM22

0.79	Translocase of outer mitochondrial membrane 22

0.69	GO:0006886	intracellular protein transport
0.46	GO:0090151	establishment of protein localization to mitochondrial membrane
0.45	GO:0001889	liver development
0.45	GO:1990542	mitochondrial transmembrane transport
0.45	GO:0044743	protein transmembrane import into intracellular organelle
0.37	GO:2001141	regulation of RNA biosynthetic process
0.37	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.37	GO:0010468	regulation of gene expression

0.40	GO:0003690	double-stranded DNA binding
0.34	GO:0008320	protein transmembrane transporter activity

0.78	GO:0005741	mitochondrial outer membrane
0.45	GO:0032592	integral component of mitochondrial membrane
0.43	GO:0098798	mitochondrial protein complex
0.40	GO:0098796	membrane protein complex
0.34	GO:0019866	organelle inner membrane

tr|T1G491|T1G491_HELRO
Uncharacterized protein
Search

0.44	Zinc finger MYM-type protein 1

0.37	GO:0006357	regulation of transcription by RNA polymerase II
0.35	GO:0007275	multicellular organism development
0.34	GO:0046080	dUTP metabolic process
0.33	GO:0016310	phosphorylation

0.68	GO:0046983	protein dimerization activity
0.38	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.35	GO:0003677	DNA binding
0.34	GO:0004170	dUTP diphosphatase activity
0.34	GO:0016301	kinase activity
0.33	GO:0008270	zinc ion binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.37	GO:0005654	nucleoplasm
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.34	EC:3.6.1.23	GO:0004170
0.34	KEGG:R02100	GO:0004170

tr|T1G492|T1G492_HELRO
Uncharacterized protein
Search

0.40	Glycylpeptide N-tetradecanoyltransferase

0.85	GO:0006499	N-terminal protein myristoylation
0.48	GO:0018201	peptidyl-glycine modification
0.40	GO:0001701	in utero embryonic development
0.38	GO:0042180	cellular ketone metabolic process

0.85	GO:0004379	glycylpeptide N-tetradecanoyltransferase activity
0.34	GO:0000062	fatty-acyl-CoA binding
0.34	GO:0008080	N-acetyltransferase activity

0.42	GO:0019898	extrinsic component of membrane
0.40	GO:0005829	cytosol
0.37	GO:0005886	plasma membrane
0.36	GO:0005794	Golgi apparatus
0.30	GO:0031224	intrinsic component of membrane

0.85

EC:2.3.1.97

GO:0004379

tr|T1G493|T1G493_HELRO
Uncharacterized protein
Search

tr|T1G494|T1G494_HELRO
Uncharacterized protein
Search

0.56	Mitogen-activated protein kinase kinase kinase

0.65	GO:0000186	activation of MAPKK activity
0.63	GO:0006468	protein phosphorylation
0.63	GO:0043507	positive regulation of JUN kinase activity
0.62	GO:0031098	stress-activated protein kinase signaling cascade
0.53	GO:0000187	activation of MAPK activity
0.47	GO:0008283	cell proliferation
0.44	GO:0007017	microtubule-based process
0.44	GO:0043065	positive regulation of apoptotic process
0.40	GO:0008219	cell death
0.38	GO:1901216	positive regulation of neuron death

0.66	GO:0004709	MAP kinase kinase kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0031435	mitogen-activated protein kinase kinase kinase binding
0.46	GO:0042803	protein homodimerization activity
0.39	GO:0031434	mitogen-activated protein kinase kinase binding
0.38	GO:0048365	Rac GTPase binding
0.36	GO:0043425	bHLH transcription factor binding

0.47	GO:0005813	centrosome
0.45	GO:0005874	microtubule
0.36	GO:0005737	cytoplasm
0.33	GO:0071944	cell periphery
0.30	GO:0016020	membrane

0.66

EC:2.7.11 EC:2.7.11.25

GO:0004709

tr|T1G495|T1G495_HELRO
Uncharacterized protein
Search

tr|T1G496|T1G496_HELRO
Uncharacterized protein
Search

MYCBP

0.80	c-Myc-binding protein homolog

0.57	GO:0006355	regulation of transcription, DNA-templated
0.36	GO:0045880	positive regulation of smoothened signaling pathway
0.35	GO:0006511	ubiquitin-dependent protein catabolic process
0.34	GO:0016573	histone acetylation

0.79	GO:0003713	transcription coactivator activity
0.37	GO:0003700	DNA binding transcription factor activity
0.35	GO:0031625	ubiquitin protein ligase binding
0.34	GO:0004402	histone acetyltransferase activity

0.35	GO:0031461	cullin-RING ubiquitin ligase complex
0.30	GO:0016020	membrane

0.34

GO:0004402

tr|T1G497|T1G497_HELRO
Uncharacterized protein
Search

0.53	GO:0055114	oxidation-reduction process
0.34	GO:0007618	mating
0.33	GO:0017062	respiratory chain complex III assembly
0.33	GO:0097033	mitochondrial respiratory chain complex III biogenesis
0.33	GO:0033108	mitochondrial respiratory chain complex assembly
0.32	GO:0032259	methylation
0.32	GO:0006357	regulation of transcription by RNA polymerase II

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.66	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.32	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.32	GO:0008168	methyltransferase activity
0.32	GO:0008270	zinc ion binding
0.32	GO:0003723	RNA binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding

0.33	GO:0005789	endoplasmic reticulum membrane
0.32	GO:0031090	organelle membrane
0.32	GO:0005634	nucleus
0.32	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

tr|T1G498|T1G498_HELRO
Uncharacterized protein
Search

tr|T1G499|T1G499_HELRO
Uncharacterized protein
Search

tr|T1G4A0|T1G4A0_HELRO
Uncharacterized protein
Search

tr|T1G4A1|T1G4A1_HELRO
Uncharacterized protein
Search

0.21	ATP-dependent DNA helicase

0.78	GO:0000723	telomere maintenance
0.70	GO:0032392	DNA geometric change
0.65	GO:0006310	DNA recombination
0.65	GO:0006281	DNA repair
0.33	GO:0006030	chitin metabolic process
0.33	GO:0071526	semaphorin-plexin signaling pathway
0.33	GO:0006508	proteolysis
0.32	GO:0007017	microtubule-based process
0.32	GO:0007010	cytoskeleton organization

0.70	GO:0003678	DNA helicase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0008234	cysteine-type peptidase activity
0.33	GO:0017154	semaphorin receptor activity
0.33	GO:0005200	structural constituent of cytoskeleton
0.33	GO:0008289	lipid binding
0.32	GO:0016758	transferase activity, transferring hexosyl groups
0.32	GO:0032550	purine ribonucleoside binding

0.33	GO:0005874	microtubule
0.32	GO:0005783	endoplasmic reticulum
0.30	GO:0016020	membrane

0.34

GO:0008234

tr|T1G4A2|T1G4A2_HELRO
Uncharacterized protein
Search

ELP3

0.72	Elongator complex protein 3

0.73	GO:0016573	histone acetylation
0.55	GO:0006351	transcription, DNA-templated
0.54	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.53	GO:0010468	regulation of gene expression
0.49	GO:0048699	generation of neurons
0.49	GO:0045859	regulation of protein kinase activity
0.48	GO:0051270	regulation of cellular component movement
0.48	GO:0040012	regulation of locomotion
0.46	GO:0007417	central nervous system development

0.74	GO:0004402	histone acetyltransferase activity
0.64	GO:0051536	iron-sulfur cluster binding
0.56	GO:0008607	phosphorylase kinase regulator activity
0.51	GO:0046872	metal ion binding
0.51	GO:0000993	RNA polymerase II core binding

0.53	GO:0033588	Elongator holoenzyme complex
0.50	GO:0008023	transcription elongation factor complex
0.47	GO:0000123	histone acetyltransferase complex
0.46	GO:0005730	nucleolus
0.39	GO:0005737	cytoplasm
0.38	GO:0045202	synapse

0.74

GO:0004402

tr|T1G4A3|T1G4A3_HELRO
Uncharacterized protein
Search

WDR46

0.86	WD repeat-containing protein 46

0.68	GO:1903955	positive regulation of protein targeting to mitochondrion
0.63	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.50	GO:0000479	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.49	GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.48	GO:0000967	rRNA 5'-end processing

0.37

GO:0003723

RNA binding

0.62	GO:0032040	small-subunit processome
0.61	GO:0005730	nucleolus
0.59	GO:0030686	90S preribosome
0.50	GO:0030688	preribosome, small subunit precursor
0.38	GO:0005581	collagen trimer
0.37	GO:0005654	nucleoplasm
0.35	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

tr|T1G4A4|T1G4A4_HELRO
Uncharacterized protein
Search

tr|T1G4A5|T1G4A5_HELRO
Uncharacterized protein
Search

0.23	Aminopeptidase N

0.61	GO:0006508	proteolysis
0.46	GO:0008217	regulation of blood pressure
0.45	GO:0043171	peptide catabolic process
0.42	GO:0060177	regulation of angiotensin metabolic process
0.42	GO:0050886	endocrine process
0.40	GO:0042445	hormone metabolic process
0.39	GO:0051604	protein maturation
0.38	GO:0007267	cell-cell signaling
0.38	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I
0.36	GO:0007165	signal transduction

0.69	GO:0004177	aminopeptidase activity
0.67	GO:0008237	metallopeptidase activity
0.63	GO:0008270	zinc ion binding
0.45	GO:0042277	peptide binding
0.35	GO:0104005	hijacked molecular function
0.33	GO:0004872	receptor activity

0.41	GO:0009897	external side of plasma membrane
0.40	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.40	GO:0070062	extracellular exosome
0.36	GO:0012505	endomembrane system
0.36	GO:0005765	lysosomal membrane
0.35	GO:0031984	organelle subcompartment
0.34	GO:0099503	secretory vesicle
0.34	GO:0030659	cytoplasmic vesicle membrane
0.30	GO:0016021	integral component of membrane

0.69

EC:3.4.11

GO:0004177

tr|T1G4A6|T1G4A6_HELRO
Uncharacterized protein
Search

tr|T1G4A7|T1G4A7_HELRO
Uncharacterized protein
Search

NKIRAS2

0.79	NF-kappa-B inhibitor-interacting Ras-like protein 1

0.60	GO:0007165	signal transduction
0.32	GO:0006468	protein phosphorylation

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032553	ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0004672	protein kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0008144	drug binding

0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|T1G4A8|T1G4A8_HELRO
Diacylglycerol kinase
Search

0.44	Diacylglycerol kinase

0.83	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway
0.57	GO:0016310	phosphorylation
0.55	GO:0035556	intracellular signal transduction
0.41	GO:2000292	regulation of defecation
0.41	GO:0032094	response to food
0.41	GO:0046662	regulation of oviposition
0.40	GO:0007271	synaptic transmission, cholinergic
0.40	GO:0007212	dopamine receptor signaling pathway
0.40	GO:0007210	serotonin receptor signaling pathway
0.39	GO:0040013	negative regulation of locomotion

0.80	GO:0004143	diacylglycerol kinase activity
0.75	GO:0003951	NAD+ kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0046872	metal ion binding
0.46	GO:0003723	RNA binding
0.39	GO:0017048	Rho GTPase binding

0.42	GO:0005622	intracellular
0.39	GO:0044297	cell body
0.39	GO:0030424	axon
0.30	GO:0016020	membrane

0.80	EC:2.7.1.107	GO:0004143
0.75	KEGG:R00104	GO:0003951

tr|T1G4A9|T1G4A9_HELRO
Uncharacterized protein
Search

0.39	Fibroblast growth factor receptor 1

0.78	GO:0008543	fibroblast growth factor receptor signaling pathway
0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.73	GO:0008284	positive regulation of cell proliferation
0.50	GO:0046777	protein autophosphorylation
0.50	GO:0043410	positive regulation of MAPK cascade
0.49	GO:0070857	regulation of bile acid biosynthetic process
0.49	GO:0010715	regulation of extracellular matrix disassembly
0.49	GO:0070372	regulation of ERK1 and ERK2 cascade
0.49	GO:0051054	positive regulation of DNA metabolic process
0.47	GO:0043085	positive regulation of catalytic activity

0.82	GO:0005007	fibroblast growth factor-activated receptor activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.53	GO:0017134	fibroblast growth factor binding
0.45	GO:1901681	sulfur compound binding
0.41	GO:0042802	identical protein binding
0.40	GO:0090722	receptor-receptor interaction
0.36	GO:0046983	protein dimerization activity

0.47	GO:0030133	transport vesicle
0.45	GO:0005794	Golgi apparatus
0.45	GO:0005911	cell-cell junction
0.45	GO:0005783	endoplasmic reticulum
0.44	GO:0005887	integral component of plasma membrane
0.38	GO:0043235	receptor complex
0.37	GO:0005730	nucleolus
0.36	GO:0005768	endosome
0.35	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0005764	lysosome

0.36	EC:2.7.1.153	GO:0046934
0.36	KEGG:R04545	GO:0046934

tr|T1G4B0|T1G4B0_HELRO
Uncharacterized protein
Search

0.69	TNF receptor-associated factor 1 (Fragment)

0.74	GO:0042981	regulation of apoptotic process
0.66	GO:0033209	tumor necrosis factor-mediated signaling pathway
0.60	GO:0007250	activation of NF-kappaB-inducing kinase activity
0.59	GO:0051865	protein autoubiquitination
0.57	GO:0046328	regulation of JNK cascade
0.57	GO:0051090	regulation of DNA binding transcription factor activity
0.56	GO:0002697	regulation of immune effector process
0.55	GO:0001817	regulation of cytokine production
0.52	GO:1903721	positive regulation of I-kappaB phosphorylation
0.52	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway

0.78	GO:0005164	tumor necrosis factor receptor binding
0.61	GO:0008270	zinc ion binding
0.53	GO:0031996	thioesterase binding
0.53	GO:0004842	ubiquitin-protein transferase activity
0.52	GO:0005174	CD40 receptor binding
0.50	GO:0046625	sphingolipid binding
0.49	GO:0031625	ubiquitin protein ligase binding
0.48	GO:0019903	protein phosphatase binding
0.47	GO:0042802	identical protein binding
0.47	GO:0019901	protein kinase binding

0.52	GO:1990597	AIP1-IRE1 complex
0.52	GO:0097057	TRAF2-GSTP1 complex
0.51	GO:1990604	IRE1-TRAF2-ASK1 complex
0.51	GO:0035631	CD40 receptor complex
0.47	GO:0098857	membrane microdomain
0.46	GO:0009898	cytoplasmic side of plasma membrane
0.46	GO:0012506	vesicle membrane
0.46	GO:0000151	ubiquitin ligase complex
0.43	GO:0005829	cytosol
0.36	GO:0005938	cell cortex

0.35	EC:2.8.2.11	GO:0001733
0.53	KEGG:R03876	GO:0004842

tr|T1G4B1|T1G4B1_HELRO
Uncharacterized protein
Search

0.79	Nicotinic acetylcholine receptor alpha subunit

0.76	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.42	GO:0030431	sleep
0.38	GO:0017085	response to insecticide
0.38	GO:0007271	synaptic transmission, cholinergic
0.33	GO:0006468	protein phosphorylation
0.33	GO:0006812	cation transport

0.79	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0099600	transmembrane receptor activity
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003676	nucleic acid binding

0.76	GO:0045211	postsynaptic membrane
0.71	GO:0030054	cell junction
0.43	GO:0005892	acetylcholine-gated channel complex

tr|T1G4B2|T1G4B2_HELRO
Uncharacterized protein
Search

0.69	GO:0006278	RNA-dependent DNA biosynthetic process
0.38	GO:0035246	peptidyl-arginine N-methylation
0.37	GO:0035335	peptidyl-tyrosine dephosphorylation
0.36	GO:0006869	lipid transport

0.69	GO:0003964	RNA-directed DNA polymerase activity
0.37	GO:0005319	lipid transporter activity
0.37	GO:0004725	protein tyrosine phosphatase activity
0.35	GO:0008168	methyltransferase activity
0.35	GO:0008270	zinc ion binding

0.30

GO:0031224

intrinsic component of membrane

0.69

GO:0003964

tr|T1G4B3|T1G4B3_HELRO
Uncharacterized protein
Search

tr|T1G4B4|T1G4B4_HELRO
Uncharacterized protein
Search

KBP

0.88	KIF1-binding protein homolog

0.75	GO:0006839	mitochondrial transport
0.51	GO:0007399	nervous system development
0.49	GO:0030154	cell differentiation
0.45	GO:1990535	neuron projection maintenance
0.44	GO:0048915	posterior lateral line system development
0.42	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.41	GO:0000226	microtubule cytoskeleton organization

0.80	GO:0019894	kinesin binding
0.39	GO:0042578	phosphoric ester hydrolase activity
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0003676	nucleic acid binding

0.59	GO:0005739	mitochondrion
0.48	GO:0005856	cytoskeleton

0.39

EC:3.1

GO:0042578

tr|T1G4B5|T1G4B5_HELRO
Uncharacterized protein
Search

tr|T1G4B6|T1G4B6_HELRO
Uncharacterized protein
Search

THOC1

0.91	LOW QUALITY PROTEIN: THO complex subunit 1

0.59	GO:0007165	signal transduction
0.56	GO:0048297	negative regulation of isotype switching to IgA isotypes
0.54	GO:0046784	viral mRNA export from host cell nucleus
0.54	GO:2000002	negative regulation of DNA damage checkpoint
0.51	GO:0031297	replication fork processing
0.50	GO:0032786	positive regulation of DNA-templated transcription, elongation
0.50	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.49	GO:0006915	apoptotic process
0.48	GO:0051028	mRNA transport
0.48	GO:0006405	RNA export from nucleus

0.34	GO:0005515	protein binding
0.34	GO:0003723	RNA binding
0.33	GO:0030246	carbohydrate binding
0.33	GO:0003677	DNA binding

0.52	GO:0045171	intercellular bridge
0.52	GO:0000445	THO complex part of transcription export complex
0.50	GO:0016607	nuclear speck
0.50	GO:0000784	nuclear chromosome, telomeric region
0.46	GO:0005829	cytosol
0.36	GO:0016363	nuclear matrix
0.34	GO:0005581	collagen trimer

tr|T1G4B7|T1G4B7_HELRO
Uncharacterized protein
Search

EXOG

0.96	Nuclease EXOG, mitochondrial

0.51	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.42	GO:0016579	protein deubiquitination
0.41	GO:0035234	ectopic germ cell programmed cell death
0.41	GO:0006511	ubiquitin-dependent protein catabolic process
0.40	GO:0000001	mitochondrion inheritance
0.40	GO:0007286	spermatid development
0.36	GO:0006259	DNA metabolic process
0.36	GO:0030262	apoptotic nuclear changes
0.35	GO:0016070	RNA metabolic process
0.34	GO:0043547	positive regulation of GTPase activity

0.54	GO:0046872	metal ion binding
0.52	GO:0004519	endonuclease activity
0.51	GO:0003676	nucleic acid binding
0.49	GO:0008409	5'-3' exonuclease activity
0.42	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.38	GO:0004536	deoxyribonuclease activity
0.38	GO:0004540	ribonuclease activity
0.34	GO:0005096	GTPase activator activity
0.34	GO:0044540	L-cystine L-cysteine-lyase (deaminating)
0.34	GO:0080146	L-cysteine desulfhydrase activity

0.43	GO:0031966	mitochondrial membrane
0.43	GO:0019866	organelle inner membrane
0.42	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.42	EC:3.4.19.12	GO:0036459
0.34	KEGG:R02408	GO:0044540

tr|T1G4B8|T1G4B8_HELRO
Uncharacterized protein
Search

0.60	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.45	GO:0030522	intracellular receptor signaling pathway
0.38	GO:0048386	positive regulation of retinoic acid receptor signaling pathway
0.37	GO:1902679	negative regulation of RNA biosynthetic process
0.35	GO:1902680	positive regulation of RNA biosynthetic process
0.35	GO:0042738	exogenous drug catabolic process

0.65	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0003707	steroid hormone receptor activity
0.38	GO:0001012	RNA polymerase II regulatory region DNA binding
0.37	GO:0003690	double-stranded DNA binding
0.37	GO:0042826	histone deacetylase binding
0.36	GO:0042803	protein homodimerization activity
0.32	GO:0008144	drug binding

0.61	GO:0005634	nucleus
0.36	GO:0043233	organelle lumen
0.35	GO:0044446	intracellular organelle part
0.34	GO:0005829	cytosol
0.34	GO:0045111	intermediate filament cytoskeleton
0.30	GO:0016020	membrane

tr|T1G4B9|T1G4B9_HELRO
Uncharacterized protein
Search

0.54	Angiopoietin-4

0.63	GO:0001525	angiogenesis
0.61	GO:0043066	negative regulation of apoptotic process
0.52	GO:0006508	proteolysis
0.46	GO:0051005	negative regulation of lipoprotein lipase activity
0.45	GO:2000351	regulation of endothelial cell apoptotic process
0.45	GO:0070328	triglyceride homeostasis
0.42	GO:0007596	blood coagulation
0.40	GO:1902262	apoptotic process involved in blood vessel morphogenesis
0.38	GO:0001666	response to hypoxia
0.38	GO:0019216	regulation of lipid metabolic process

0.52	GO:0008233	peptidase activity
0.43	GO:0004857	enzyme inhibitor activity
0.42	GO:0042802	identical protein binding
0.36	GO:0001104	RNA polymerase II transcription cofactor activity
0.35	GO:0030674	protein binding, bridging
0.34	GO:0008270	zinc ion binding
0.34	GO:0005102	receptor binding
0.34	GO:0003723	RNA binding

0.58	GO:0005615	extracellular space
0.37	GO:0005578	proteinaceous extracellular matrix
0.36	GO:0016592	mediator complex
0.30	GO:0016020	membrane

0.52

GO:0008233

tr|T1G4C0|T1G4C0_HELRO
Uncharacterized protein
Search

0.45

Tenascin

0.75	GO:0001525	angiogenesis
0.72	GO:0043066	negative regulation of apoptotic process
0.54	GO:0051005	negative regulation of lipoprotein lipase activity
0.52	GO:0070328	triglyceride homeostasis
0.50	GO:2000351	regulation of endothelial cell apoptotic process
0.45	GO:0007596	blood coagulation
0.43	GO:0019216	regulation of lipid metabolic process
0.42	GO:0007155	cell adhesion
0.41	GO:0001666	response to hypoxia
0.40	GO:0051260	protein homooligomerization

0.48	GO:0004857	enzyme inhibitor activity
0.46	GO:0042802	identical protein binding
0.40	GO:0005509	calcium ion binding
0.39	GO:0005178	integrin binding
0.38	GO:0042302	structural constituent of cuticle
0.38	GO:0008083	growth factor activity
0.36	GO:0030674	protein binding, bridging
0.35	GO:0003723	RNA binding

0.68	GO:0005615	extracellular space
0.40	GO:0005578	proteinaceous extracellular matrix
0.38	GO:0005769	early endosome
0.37	GO:0009986	cell surface
0.37	GO:0005794	Golgi apparatus
0.34	GO:0043234	protein complex
0.30	GO:0016020	membrane

tr|T1G4C1|T1G4C1_HELRO
Uncharacterized protein
Search

VMA21

0.83	Vacuolar ATPase assembly integral membrane protein VMA21

0.84	GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly
0.35	GO:0043462	regulation of ATPase activity

0.78	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane
0.72	GO:0012507	ER to Golgi transport vesicle membrane
0.65	GO:0005789	endoplasmic reticulum membrane
0.50	GO:0005764	lysosome
0.30	GO:0031224	intrinsic component of membrane

tr|T1G4C2|T1G4C2_HELRO
Uncharacterized protein
Search

0.58	GO:0007155	cell adhesion
0.52	GO:0042981	regulation of apoptotic process
0.50	GO:0016055	Wnt signaling pathway
0.46	GO:0045186	zonula adherens assembly
0.46	GO:0072205	metanephric collecting duct development
0.46	GO:0071896	protein localization to adherens junction
0.46	GO:0035332	positive regulation of hippo signaling
0.46	GO:0035331	negative regulation of hippo signaling
0.45	GO:0030859	polarized epithelial cell differentiation
0.45	GO:0060999	positive regulation of dendritic spine development

0.67	GO:0008022	protein C-terminus binding
0.44	GO:0008013	beta-catenin binding
0.41	GO:0008092	cytoskeletal protein binding

0.71	GO:0043220	Schmidt-Lanterman incisure
0.70	GO:0016327	apicolateral plasma membrane
0.65	GO:0016324	apical plasma membrane
0.64	GO:0005923	bicellular tight junction
0.59	GO:0031410	cytoplasmic vesicle
0.50	GO:0014069	postsynaptic density
0.47	GO:0120038	plasma membrane bounded cell projection part
0.44	GO:0005913	cell-cell adherens junction
0.43	GO:0097447	dendritic tree
0.43	GO:0045211	postsynaptic membrane

tr|T1G4C3|T1G4C3_HELRO
Uncharacterized protein
Search

0.46

Tenascin

0.65	GO:0007596	blood coagulation
0.54	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.51	GO:0048514	blood vessel morphogenesis
0.48	GO:0010519	negative regulation of phospholipase activity
0.48	GO:0051005	negative regulation of lipoprotein lipase activity
0.47	GO:0055091	phospholipid homeostasis
0.46	GO:0050996	positive regulation of lipid catabolic process
0.46	GO:0070328	triglyceride homeostasis
0.46	GO:0060840	artery development
0.46	GO:0042632	cholesterol homeostasis

0.50	GO:0005509	calcium ion binding
0.46	GO:0004859	phospholipase inhibitor activity
0.46	GO:0005102	receptor binding
0.45	GO:0001104	RNA polymerase II transcription cofactor activity
0.44	GO:0050839	cell adhesion molecule binding
0.43	GO:0030545	receptor regulator activity
0.43	GO:0032403	protein complex binding
0.42	GO:0030674	protein binding, bridging

0.50	GO:0005615	extracellular space
0.44	GO:0016592	mediator complex
0.44	GO:0005769	early endosome
0.43	GO:0009986	cell surface
0.42	GO:0005794	Golgi apparatus
0.30	GO:0031224	intrinsic component of membrane

tr|T1G4C4|T1G4C4_HELRO
Uncharacterized protein
Search

0.62	Angiopoietin-related protein 4 (Fragment)

0.76	GO:0001525	angiogenesis
0.73	GO:0043066	negative regulation of apoptotic process
0.55	GO:0051005	negative regulation of lipoprotein lipase activity
0.52	GO:0070328	triglyceride homeostasis
0.51	GO:2000351	regulation of endothelial cell apoptotic process
0.48	GO:0007596	blood coagulation
0.43	GO:0019216	regulation of lipid metabolic process
0.41	GO:0001666	response to hypoxia
0.40	GO:0051260	protein homooligomerization
0.40	GO:1902262	apoptotic process involved in blood vessel morphogenesis

0.49	GO:0004857	enzyme inhibitor activity
0.46	GO:0042802	identical protein binding
0.39	GO:0005178	integrin binding
0.38	GO:0008083	growth factor activity
0.35	GO:0003723	RNA binding

0.69	GO:0005615	extracellular space
0.40	GO:0005578	proteinaceous extracellular matrix
0.38	GO:0005769	early endosome
0.37	GO:0009986	cell surface
0.37	GO:0005794	Golgi apparatus
0.30	GO:0016020	membrane

tr|T1G4C5|T1G4C5_HELRO
Uncharacterized protein
Search

HCFC1

0.64	Host cell factor 1 (Fragment)

0.51	GO:0019045	latent virus replication
0.50	GO:0043982	histone H4-K8 acetylation
0.50	GO:0043981	histone H4-K5 acetylation
0.50	GO:0043984	histone H4-K16 acetylation
0.47	GO:0050821	protein stabilization
0.45	GO:0006366	transcription by RNA polymerase II
0.45	GO:0045944	positive regulation of transcription by RNA polymerase II
0.43	GO:0043254	regulation of protein complex assembly
0.37	GO:0000122	negative regulation of transcription by RNA polymerase II
0.36	GO:0071407	cellular response to organic cyclic compound

0.51	GO:0043996	histone acetyltransferase activity (H4-K8 specific)
0.51	GO:0046972	histone acetyltransferase activity (H4-K16 specific)
0.51	GO:0043995	histone acetyltransferase activity (H4-K5 specific)
0.50	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding
0.49	GO:0033613	activating transcription factor binding
0.47	GO:0045296	cadherin binding
0.47	GO:0030674	protein binding, bridging
0.47	GO:0003713	transcription coactivator activity
0.46	GO:0003682	chromatin binding
0.45	GO:0042802	identical protein binding

0.82	GO:0071339	MLL1 complex
0.81	GO:0048188	Set1C/COMPASS complex
0.49	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex
0.48	GO:0043025	neuronal cell body
0.47	GO:0070461	SAGA-type complex
0.37	GO:0005737	cytoplasm
0.37	GO:0030425	dendrite
0.37	GO:0030424	axon
0.30	GO:0031224	intrinsic component of membrane

tr|T1G4C6|T1G4C6_HELRO
Uncharacterized protein
Search

0.54	Potassium voltage-gated channel subfamily H member 7

0.73	GO:0071805	potassium ion transmembrane transport
0.73	GO:0034765	regulation of ion transmembrane transport
0.47	GO:0042391	regulation of membrane potential
0.44	GO:0044057	regulation of system process
0.42	GO:0035637	multicellular organismal signaling
0.39	GO:0046662	regulation of oviposition
0.39	GO:0007617	mating behavior
0.36	GO:0023014	signal transduction by protein phosphorylation
0.36	GO:0009308	amine metabolic process
0.36	GO:0000160	phosphorelay signal transduction system

0.78	GO:0005249	voltage-gated potassium channel activity
0.38	GO:0008131	primary amine oxidase activity
0.36	GO:0000155	phosphorelay sensor kinase activity
0.36	GO:0048038	quinone binding
0.36	GO:0005507	copper ion binding

0.43	GO:0005887	integral component of plasma membrane
0.33	GO:0005622	intracellular

0.38	EC:1.4.3.21	GO:0008131
0.38	KEGG:R01853	GO:0008131

tr|T1G4C7|T1G4C7_HELRO
Uncharacterized protein
Search

0.55	Matrix metalloproteinase (Fragment)

0.61	GO:0006508	proteolysis
0.43	GO:0030334	regulation of cell migration
0.41	GO:0006954	inflammatory response
0.39	GO:0030574	collagen catabolic process
0.36	GO:0010727	negative regulation of hydrogen peroxide metabolic process
0.36	GO:0097374	sensory neuron axon guidance
0.35	GO:0032461	positive regulation of protein oligomerization
0.35	GO:0022617	extracellular matrix disassembly

0.70	GO:0004222	metalloendopeptidase activity
0.63	GO:0008270	zinc ion binding
0.34	GO:0004252	serine-type endopeptidase activity

0.74	GO:0031012	extracellular matrix
0.34	GO:0005615	extracellular space
0.34	GO:0005581	collagen trimer
0.30	GO:0016020	membrane

0.70

GO:0004222

tr|T1G4C8|T1G4C8_HELRO
Phosphodiesterase
Search

PDE1B

0.55	Phosphodiesterase

0.60	GO:0007165	signal transduction
0.50	GO:0046069	cGMP catabolic process
0.49	GO:0036006	cellular response to macrophage colony-stimulating factor stimulus
0.49	GO:0042053	regulation of dopamine metabolic process
0.49	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus
0.49	GO:0001975	response to amphetamine
0.49	GO:0042428	serotonin metabolic process
0.49	GO:1903131	mononuclear cell differentiation
0.48	GO:0008542	visual learning
0.48	GO:0006198	cAMP catabolic process

0.78	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.53	GO:0046872	metal ion binding
0.36	GO:0005516	calmodulin binding

0.36	GO:0043025	neuronal cell body
0.34	GO:0005929	cilium
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.78

GO:0004114

tr|T1G4C9|T1G4C9_HELRO
Uncharacterized protein
Search

0.75	GO:0001525	angiogenesis
0.72	GO:0043066	negative regulation of apoptotic process
0.54	GO:0051005	negative regulation of lipoprotein lipase activity
0.52	GO:0070328	triglyceride homeostasis
0.51	GO:2000351	regulation of endothelial cell apoptotic process
0.45	GO:0007596	blood coagulation
0.43	GO:0019216	regulation of lipid metabolic process
0.42	GO:0007155	cell adhesion
0.41	GO:0001666	response to hypoxia
0.40	GO:0051260	protein homooligomerization

0.49	GO:0004857	enzyme inhibitor activity
0.46	GO:0042802	identical protein binding
0.40	GO:0005509	calcium ion binding
0.38	GO:0005178	integrin binding
0.37	GO:0042302	structural constituent of cuticle
0.37	GO:0008083	growth factor activity
0.36	GO:0030674	protein binding, bridging
0.35	GO:0003723	RNA binding

0.69	GO:0005615	extracellular space
0.40	GO:0005578	proteinaceous extracellular matrix
0.38	GO:0005769	early endosome
0.37	GO:0009986	cell surface
0.36	GO:0005794	Golgi apparatus
0.34	GO:0043234	protein complex
0.30	GO:0016020	membrane

tr|T1G4D0|T1G4D0_HELRO
Uncharacterized protein
Search

SLC18A2

0.80	Synaptic vesicular amine transporter

0.58	GO:0006855	drug transmembrane transport
0.54	GO:0015842	aminergic neurotransmitter loading into synaptic vesicle
0.52	GO:0015844	monoamine transport
0.51	GO:0001975	response to amphetamine
0.49	GO:0015850	organic hydroxy compound transport
0.49	GO:0007626	locomotory behavior
0.48	GO:0015696	ammonium transport
0.47	GO:0007275	multicellular organism development
0.47	GO:1904647	response to rotenone
0.43	GO:0045117	azole transport

0.58	GO:0015238	drug transmembrane transporter activity
0.52	GO:0008504	monoamine transmembrane transporter activity
0.45	GO:1901618	organic hydroxy compound transmembrane transporter activity
0.45	GO:0005326	neurotransmitter transporter activity
0.45	GO:0008519	ammonium transmembrane transporter activity
0.35	GO:0005549	odorant binding
0.35	GO:0004984	olfactory receptor activity
0.34	GO:0031072	heat shock protein binding
0.34	GO:0005275	amine transmembrane transporter activity
0.33	GO:0005249	voltage-gated potassium channel activity

0.49	GO:0098793	presynapse
0.44	GO:0099503	secretory vesicle
0.43	GO:0030133	transport vesicle
0.42	GO:0031594	neuromuscular junction
0.42	GO:0005887	integral component of plasma membrane
0.37	GO:0030659	cytoplasmic vesicle membrane
0.35	GO:0060198	clathrin-sculpted vesicle
0.35	GO:0098805	whole membrane
0.34	GO:0098588	bounding membrane of organelle
0.34	GO:0044306	neuron projection terminus

tr|T1G4D1|T1G4D1_HELRO
Uncharacterized protein
Search

CWC15

0.96	Spliceosome-associated protein CWC15

0.75

GO:0000398

mRNA splicing, via spliceosome

0.36	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.76	GO:0005681	spliceosomal complex
0.48	GO:0016607	nuclear speck
0.42	GO:1902494	catalytic complex
0.41	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

tr|T1G4D2|T1G4D2_HELRO
Uncharacterized protein
Search

0.70	Tropomyosin beta chain

0.61	GO:0060298	positive regulation of sarcomere organization
0.58	GO:0006936	muscle contraction
0.55	GO:0007507	heart development
0.54	GO:0007015	actin filament organization
0.48	GO:0034609	spicule insertion
0.43	GO:0043393	regulation of protein binding
0.43	GO:0030835	negative regulation of actin filament depolymerization
0.42	GO:0009792	embryo development ending in birth or egg hatching
0.42	GO:0030833	regulation of actin filament polymerization
0.40	GO:0006413	translational initiation

0.61	GO:0008307	structural constituent of muscle
0.56	GO:0051015	actin filament binding
0.40	GO:0003743	translation initiation factor activity
0.37	GO:0003700	DNA binding transcription factor activity
0.35	GO:0003677	DNA binding

0.63	GO:0005862	muscle thin filament tropomyosin
0.58	GO:0005884	actin filament
0.37	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|T1G4D3|T1G4D3_HELRO
Uncharacterized protein
Search

tr|T1G4D4|T1G4D4_HELRO
Uncharacterized protein
Search

0.97	T-cell acute lymphocytic leukemia protein 1 (Fragment)

0.55	GO:0060217	hemangioblast cell differentiation
0.54	GO:0060375	regulation of mast cell differentiation
0.53	GO:0060018	astrocyte fate commitment
0.53	GO:0030221	basophil differentiation
0.53	GO:0060216	definitive hemopoiesis
0.52	GO:0060218	hematopoietic stem cell differentiation
0.52	GO:0043249	erythrocyte maturation
0.52	GO:0021527	spinal cord association neuron differentiation
0.52	GO:0035855	megakaryocyte development
0.52	GO:0030220	platelet formation

0.68	GO:0046983	protein dimerization activity
0.51	GO:0070888	E-box binding
0.51	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.50	GO:0042826	histone deacetylase binding
0.49	GO:0001085	RNA polymerase II transcription factor binding
0.49	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.47	GO:0003682	chromatin binding

0.53	GO:0033193	Lsd1/2 complex
0.49	GO:0000118	histone deacetylase complex
0.46	GO:0005667	transcription factor complex
0.46	GO:0000790	nuclear chromatin
0.30	GO:0016021	integral component of membrane

tr|T1G4D5|T1G4D5_HELRO
Uncharacterized protein
Search

SLC18A2

0.39	Synaptic vesicular amine transporter

0.60	GO:0006855	drug transmembrane transport
0.53	GO:0015842	aminergic neurotransmitter loading into synaptic vesicle
0.51	GO:0015844	monoamine transport
0.50	GO:0001975	response to amphetamine
0.49	GO:0007626	locomotory behavior
0.48	GO:0015850	organic hydroxy compound transport
0.47	GO:0015696	ammonium transport
0.46	GO:0009791	post-embryonic development
0.44	GO:1904647	response to rotenone
0.44	GO:1904340	positive regulation of dopaminergic neuron differentiation

0.60	GO:0015238	drug transmembrane transporter activity
0.51	GO:0008504	monoamine transmembrane transporter activity
0.45	GO:1901618	organic hydroxy compound transmembrane transporter activity
0.45	GO:0005326	neurotransmitter transporter activity
0.45	GO:0008519	ammonium transmembrane transporter activity
0.35	GO:0005549	odorant binding
0.35	GO:0004984	olfactory receptor activity
0.34	GO:0031072	heat shock protein binding
0.33	GO:0005275	amine transmembrane transporter activity
0.33	GO:0005249	voltage-gated potassium channel activity

0.48	GO:0098793	presynapse
0.43	GO:0099503	secretory vesicle
0.42	GO:0030133	transport vesicle
0.41	GO:0005887	integral component of plasma membrane
0.41	GO:0031594	neuromuscular junction
0.36	GO:0030659	cytoplasmic vesicle membrane
0.35	GO:0060198	clathrin-sculpted vesicle
0.34	GO:0098805	whole membrane
0.34	GO:0098588	bounding membrane of organelle
0.34	GO:0044306	neuron projection terminus

tr|T1G4D6|T1G4D6_HELRO
Uncharacterized protein
Search

WDR19

0.93	WD repeat-containing protein 19

0.86	GO:0060830	ciliary receptor clustering involved in smoothened signaling pathway
0.86	GO:0035721	intraciliary retrograde transport
0.86	GO:0061055	myotome development
0.85	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning
0.83	GO:0031076	embryonic camera-type eye development
0.81	GO:0048701	embryonic cranial skeleton morphogenesis
0.80	GO:0030326	embryonic limb morphogenesis
0.80	GO:0042471	ear morphogenesis
0.79	GO:0055123	digestive system development
0.79	GO:0008406	gonad development

0.35

GO:0004252

serine-type endopeptidase activity

0.85	GO:0030991	intraciliary transport particle A
0.83	GO:0032391	photoreceptor connecting cilium
0.76	GO:0031514	motile cilium
0.75	GO:0016604	nuclear body
0.43	GO:0001750	photoreceptor outer segment
0.40	GO:0097542	ciliary tip
0.40	GO:0005856	cytoskeleton
0.35	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.35

GO:0004252

tr|T1G4D7|T1G4D7_HELRO
Uncharacterized protein
Search

tr|T1G4D8|T1G4D8_HELRO
Uncharacterized protein
Search

0.80	GO:0001525	angiogenesis
0.76	GO:0043066	negative regulation of apoptotic process
0.55	GO:0051005	negative regulation of lipoprotein lipase activity
0.53	GO:2000351	regulation of endothelial cell apoptotic process
0.53	GO:0070328	triglyceride homeostasis
0.42	GO:0001666	response to hypoxia
0.42	GO:0019216	regulation of lipid metabolic process
0.41	GO:0051260	protein homooligomerization
0.40	GO:1902262	apoptotic process involved in blood vessel morphogenesis
0.39	GO:0007596	blood coagulation

0.49	GO:0004857	enzyme inhibitor activity
0.47	GO:0042802	identical protein binding
0.35	GO:0003723	RNA binding

0.72	GO:0005615	extracellular space
0.41	GO:0005578	proteinaceous extracellular matrix
0.30	GO:0016020	membrane

tr|T1G4D9|T1G4D9_HELRO
Uncharacterized protein
Search

0.10	MORN repeat containing 2

0.49	GO:0016310	phosphorylation
0.49	GO:0035082	axoneme assembly
0.49	GO:0007283	spermatogenesis
0.47	GO:0007281	germ cell development
0.43	GO:0046488	phosphatidylinositol metabolic process
0.43	GO:0030258	lipid modification
0.38	GO:0019538	protein metabolic process
0.38	GO:0043412	macromolecule modification
0.36	GO:0051321	meiotic cell cycle
0.36	GO:0032259	methylation

0.51	GO:0016301	kinase activity
0.41	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.40	GO:0140096	catalytic activity, acting on a protein
0.38	GO:0032559	adenyl ribonucleotide binding
0.38	GO:0008144	drug binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0016859	cis-trans isomerase activity
0.36	GO:0008168	methyltransferase activity
0.35	GO:0016787	hydrolase activity
0.35	GO:0046872	metal ion binding

0.50	GO:0072687	meiotic spindle
0.49	GO:0031514	motile cilium
0.48	GO:0097223	sperm part
0.47	GO:0000794	condensed nuclear chromosome
0.44	GO:0044441	ciliary part
0.42	GO:0099513	polymeric cytoskeletal fiber
0.38	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.41

GO:0016773

tr|T1G4E0|T1G4E0_HELRO
Uncharacterized protein
Search

IARS

0.65	Isoleucyl-tRNA synthetase

0.79	GO:0006428	isoleucyl-tRNA aminoacylation
0.73	GO:0106074	aminoacyl-tRNA metabolism involved in translational fidelity
0.44	GO:1903670	regulation of sprouting angiogenesis
0.35	GO:0005975	carbohydrate metabolic process

0.79	GO:0004822	isoleucine-tRNA ligase activity
0.73	GO:0002161	aminoacyl-tRNA editing activity
0.69	GO:0000049	tRNA binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0051020	GTPase binding

0.49	GO:0005737	cytoplasm
0.48	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex
0.30	GO:0016020	membrane

0.79	EC:6.1.1.5	GO:0004822
0.79	KEGG:R03656	GO:0004822

tr|T1G4E1|T1G4E1_HELRO
Uncharacterized protein
Search

0.11	RNA-binding protein MEX3B (Fragment)

0.35	GO:0072697	protein localization to cell cortex
0.34	GO:0050766	positive regulation of phagocytosis
0.34	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.34	GO:0046777	protein autophosphorylation
0.34	GO:0022409	positive regulation of cell-cell adhesion
0.34	GO:0043547	positive regulation of GTPase activity

0.59	GO:0003723	RNA binding
0.36	GO:0016874	ligase activity
0.35	GO:0032794	GTPase activating protein binding
0.33	GO:0046872	metal ion binding

0.41	GO:0005654	nucleoplasm
0.41	GO:0005829	cytosol
0.35	GO:0000932	P-body
0.30	GO:0031224	intrinsic component of membrane

0.36

GO:0016874

tr|T1G4E2|T1G4E2_HELRO
Uncharacterized protein
Search

0.73	GO:0007596	blood coagulation
0.58	GO:0010519	negative regulation of phospholipase activity
0.58	GO:0051005	negative regulation of lipoprotein lipase activity
0.57	GO:0007160	cell-matrix adhesion
0.57	GO:0055091	phospholipid homeostasis
0.56	GO:0050996	positive regulation of lipid catabolic process
0.56	GO:0070328	triglyceride homeostasis
0.55	GO:0048844	artery morphogenesis
0.55	GO:0001775	cell activation
0.55	GO:0042632	cholesterol homeostasis

0.59	GO:0005102	receptor binding
0.56	GO:0050839	cell adhesion molecule binding
0.56	GO:0004859	phospholipase inhibitor activity
0.56	GO:0030674	protein binding, bridging
0.51	GO:0030545	receptor regulator activity
0.50	GO:0032403	protein complex binding
0.42	GO:0008201	heparin binding
0.39	GO:0005198	structural molecule activity

0.59	GO:0005577	fibrinogen complex
0.54	GO:0009986	cell surface
0.53	GO:0005769	early endosome
0.49	GO:0005794	Golgi apparatus
0.46	GO:0031091	platelet alpha granule
0.42	GO:0098552	side of membrane
0.42	GO:0030027	lamellipodium
0.39	GO:0044459	plasma membrane part
0.30	GO:0016021	integral component of membrane

tr|T1G4E3|T1G4E3_HELRO
Uncharacterized protein
Search

0.77	GO:0001525	angiogenesis
0.74	GO:0043066	negative regulation of apoptotic process
0.55	GO:0051005	negative regulation of lipoprotein lipase activity
0.53	GO:0070328	triglyceride homeostasis
0.51	GO:2000351	regulation of endothelial cell apoptotic process
0.45	GO:0007596	blood coagulation
0.43	GO:0019216	regulation of lipid metabolic process
0.42	GO:0001666	response to hypoxia
0.41	GO:0051260	protein homooligomerization
0.40	GO:0010519	negative regulation of phospholipase activity

0.49	GO:0004857	enzyme inhibitor activity
0.46	GO:0042802	identical protein binding
0.39	GO:0005178	integrin binding
0.38	GO:0008083	growth factor activity
0.36	GO:0005509	calcium ion binding
0.35	GO:0003723	RNA binding

0.70	GO:0005615	extracellular space
0.40	GO:0005578	proteinaceous extracellular matrix
0.38	GO:0005769	early endosome
0.37	GO:0009986	cell surface
0.37	GO:0005794	Golgi apparatus
0.30	GO:0016020	membrane

tr|T1G4E4|T1G4E4_HELRO
Uncharacterized protein
Search

PPP6R1

0.95	Serine/threonine-protein phosphatase 6 regulatory subunit 1 (Fragment)

0.75	GO:0043666	regulation of phosphoprotein phosphatase activity
0.41	GO:0048208	COPII vesicle coating
0.39	GO:0046329	negative regulation of JNK cascade

0.79	GO:0019903	protein phosphatase binding
0.73	GO:0017048	Rho GTPase binding

0.65	GO:0005829	cytosol
0.39	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1G4E5|T1G4E5_HELRO
Uncharacterized protein
Search

0.76	Vacuolar ATP synthase subunit h

0.76	GO:0015991	ATP hydrolysis coupled proton transport
0.45	GO:0007035	vacuolar acidification
0.44	GO:0006897	endocytosis
0.42	GO:0030282	bone mineralization
0.42	GO:1902868	positive regulation of retina development in camera-type eye
0.41	GO:0060348	bone development
0.41	GO:0043473	pigmentation
0.41	GO:0061074	regulation of neural retina development
0.41	GO:0060041	retina development in camera-type eye
0.35	GO:0090383	phagosome acidification

0.81	GO:0046961	proton-transporting ATPase activity, rotational mechanism
0.33	GO:0030234	enzyme regulator activity
0.33	GO:0005515	protein binding
0.32	GO:0008270	zinc ion binding
0.32	GO:0003676	nucleic acid binding

0.84	GO:0000221	vacuolar proton-transporting V-type ATPase, V1 domain
0.45	GO:0005765	lysosomal membrane
0.35	GO:0070062	extracellular exosome
0.33	GO:0005829	cytosol
0.32	GO:0005634	nucleus
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1G4E6|T1G4E6_HELRO
Uncharacterized protein
Search

0.62	GO:0043401	steroid hormone mediated signaling pathway
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.43	GO:0031016	pancreas development
0.40	GO:1902680	positive regulation of RNA biosynthetic process
0.39	GO:0048732	gland development
0.39	GO:0009888	tissue development
0.39	GO:0021854	hypothalamus development

0.64	GO:0043565	sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.57	GO:0003707	steroid hormone receptor activity
0.39	GO:0003682	chromatin binding
0.39	GO:0044212	transcription regulatory region DNA binding
0.38	GO:0003690	double-stranded DNA binding
0.34	GO:0005543	phospholipid binding
0.33	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.33	GO:0003779	actin binding

0.61	GO:0005634	nucleus
0.38	GO:0005667	transcription factor complex
0.35	GO:0044446	intracellular organelle part
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.33

GO:0004553

tr|T1G4E7|T1G4E7_HELRO
Uncharacterized protein
Search

0.10

Ficolin-1

0.75	GO:0001525	angiogenesis
0.72	GO:0043066	negative regulation of apoptotic process
0.53	GO:0051005	negative regulation of lipoprotein lipase activity
0.51	GO:0070328	triglyceride homeostasis
0.50	GO:2000351	regulation of endothelial cell apoptotic process
0.44	GO:0007596	blood coagulation
0.42	GO:0019216	regulation of lipid metabolic process
0.42	GO:0007155	cell adhesion
0.41	GO:0001666	response to hypoxia
0.40	GO:0051260	protein homooligomerization

0.48	GO:0004857	enzyme inhibitor activity
0.45	GO:0042802	identical protein binding
0.40	GO:0005509	calcium ion binding
0.38	GO:0005178	integrin binding
0.37	GO:0042302	structural constituent of cuticle
0.37	GO:0008083	growth factor activity
0.36	GO:0030674	protein binding, bridging
0.35	GO:0003723	RNA binding

0.69	GO:0005615	extracellular space
0.39	GO:0005578	proteinaceous extracellular matrix
0.38	GO:0005769	early endosome
0.37	GO:0009986	cell surface
0.36	GO:0005794	Golgi apparatus
0.34	GO:0043234	protein complex
0.30	GO:0016020	membrane

tr|T1G4E8|T1G4E8_HELRO
Uncharacterized protein
Search

0.11	Angiopoietin-related protein 2

0.75	GO:0001525	angiogenesis
0.72	GO:0043066	negative regulation of apoptotic process
0.54	GO:0051005	negative regulation of lipoprotein lipase activity
0.52	GO:0070328	triglyceride homeostasis
0.51	GO:2000351	regulation of endothelial cell apoptotic process
0.46	GO:0007596	blood coagulation
0.43	GO:0019216	regulation of lipid metabolic process
0.41	GO:0001666	response to hypoxia
0.41	GO:0006461	protein complex assembly
0.40	GO:0010519	negative regulation of phospholipase activity

0.48	GO:0004857	enzyme inhibitor activity
0.46	GO:0042802	identical protein binding
0.40	GO:0005102	receptor binding
0.39	GO:0030674	protein binding, bridging
0.38	GO:0005328	neurotransmitter:sodium symporter activity
0.38	GO:0050839	cell adhesion molecule binding
0.37	GO:0030545	receptor regulator activity
0.37	GO:0032403	protein complex binding
0.37	GO:0005509	calcium ion binding
0.35	GO:0003723	RNA binding

0.69	GO:0005615	extracellular space
0.40	GO:0005578	proteinaceous extracellular matrix
0.38	GO:0005769	early endosome
0.37	GO:0009986	cell surface
0.37	GO:0005794	Golgi apparatus
0.35	GO:0043234	protein complex
0.30	GO:0016020	membrane

tr|T1G4E9|T1G4E9_HELRO
Palmitoyltransferase
Search

0.37	Palmitoyltransferase

0.61	GO:0018345	protein palmitoylation
0.37	GO:1903146	regulation of autophagy of mitochondrion
0.37	GO:1903955	positive regulation of protein targeting to mitochondrion

0.80	GO:0019707	protein-cysteine S-acyltransferase activity
0.79	GO:0016409	palmitoyltransferase activity
0.33	GO:0005515	protein binding

0.50	GO:0030425	dendrite
0.42	GO:0005886	plasma membrane
0.38	GO:0005794	Golgi apparatus
0.30	GO:0016021	integral component of membrane

0.80

GO:0019707

tr|T1G4F0|T1G4F0_HELRO
Uncharacterized protein
Search

0.45	Polycomb protein SCMH1 (Fragment)

0.77

GO:0018108

peptidyl-tyrosine phosphorylation

0.77	GO:0004713	protein tyrosine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.77

GO:0004713

tr|T1G4F1|T1G4F1_HELRO
Uncharacterized protein
Search

tr|T1G4F2|T1G4F2_HELRO
Uncharacterized protein
Search

0.72	GO:0097264	self proteolysis
0.62	GO:0048666	neuron development
0.56	GO:0007165	signal transduction
0.42	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.40	GO:0009653	anatomical structure morphogenesis
0.37	GO:0016043	cellular component organization
0.36	GO:0043010	camera-type eye development
0.33	GO:0006298	mismatch repair

0.41	GO:0050839	cell adhesion molecule binding
0.40	GO:0005509	calcium ion binding
0.40	GO:0042803	protein homodimerization activity
0.40	GO:0046982	protein heterodimerization activity
0.32	GO:0030983	mismatched DNA binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.30	GO:0003824	catalytic activity

0.56	GO:0005887	integral component of plasma membrane
0.40	GO:0043005	neuron projection
0.34	GO:0032300	mismatch repair complex

tr|T1G4F3|T1G4F3_HELRO
UDP-glucuronosyltransferase
Search

0.10	UDP-glucuronosyltransferase

0.50	GO:0002175	protein localization to paranode region of axon
0.49	GO:0030913	paranodal junction assembly
0.45	GO:0048812	neuron projection morphogenesis
0.45	GO:0052696	flavonoid glucuronidation
0.45	GO:0052697	xenobiotic glucuronidation
0.43	GO:0007010	cytoskeleton organization
0.43	GO:1904223	regulation of glucuronosyltransferase activity
0.42	GO:2001030	negative regulation of cellular glucuronidation
0.40	GO:0045922	negative regulation of fatty acid metabolic process
0.40	GO:0051552	flavone metabolic process

0.76	GO:0015020	glucuronosyltransferase activity
0.42	GO:0001972	retinoic acid binding
0.39	GO:0042803	protein homodimerization activity
0.39	GO:0046982	protein heterodimerization activity
0.38	GO:0019899	enzyme binding
0.37	GO:0047263	N-acylsphingosine galactosyltransferase activity
0.37	GO:0004857	enzyme inhibitor activity
0.36	GO:0005496	steroid binding
0.35	GO:0008489	UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity
0.34	GO:0005504	fatty acid binding

0.41	GO:0043231	intracellular membrane-bounded organelle
0.38	GO:0012505	endomembrane system
0.37	GO:0031984	organelle subcompartment
0.36	GO:0044444	cytoplasmic part
0.35	GO:0070062	extracellular exosome
0.34	GO:0005887	integral component of plasma membrane
0.34	GO:0070069	cytochrome complex

0.76

EC:2.4.1.17

GO:0015020

tr|T1G4F4|T1G4F4_HELRO
Uncharacterized protein
Search

CNOT7

0.76	mRNA deadenylase subunit

0.58	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
0.56	GO:0061014	positive regulation of mRNA catabolic process
0.54	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic
0.52	GO:0008284	positive regulation of cell proliferation
0.48	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening
0.48	GO:0017148	negative regulation of translation
0.47	GO:0060211	regulation of nuclear-transcribed mRNA poly(A) tail shortening
0.45	GO:0033962	cytoplasmic mRNA processing body assembly
0.45	GO:0045070	positive regulation of viral genome replication
0.45	GO:0042509	regulation of tyrosine phosphorylation of STAT protein

0.59	GO:0004535	poly(A)-specific ribonuclease activity
0.51	GO:0003676	nucleic acid binding
0.45	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.41	GO:0008134	transcription factor binding
0.35	GO:0046872	metal ion binding
0.33	GO:0003700	DNA binding transcription factor activity

0.57	GO:0030014	CCR4-NOT complex
0.50	GO:0000932	P-body
0.47	GO:0075341	host cell PML body
0.43	GO:0016607	nuclear speck
0.36	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.59

EC:3.1.13.4

GO:0004535

tr|T1G4F5|T1G4F5_HELRO
Uncharacterized protein
Search

0.46

Tenascin

0.66	GO:0007596	blood coagulation
0.55	GO:0007155	cell adhesion
0.51	GO:0048514	blood vessel morphogenesis
0.48	GO:0010519	negative regulation of phospholipase activity
0.48	GO:0051005	negative regulation of lipoprotein lipase activity
0.47	GO:0055091	phospholipid homeostasis
0.47	GO:0050996	positive regulation of lipid catabolic process
0.47	GO:0070328	triglyceride homeostasis
0.46	GO:0060840	artery development
0.46	GO:0042632	cholesterol homeostasis

0.50	GO:0005509	calcium ion binding
0.47	GO:0004859	phospholipase inhibitor activity
0.46	GO:0005102	receptor binding
0.45	GO:0001104	RNA polymerase II transcription cofactor activity
0.45	GO:0050839	cell adhesion molecule binding
0.43	GO:0030545	receptor regulator activity
0.43	GO:0032403	protein complex binding
0.43	GO:0030674	protein binding, bridging

0.51	GO:0005615	extracellular space
0.45	GO:0005769	early endosome
0.45	GO:0016592	mediator complex
0.43	GO:0009986	cell surface
0.42	GO:0005794	Golgi apparatus
0.30	GO:0031224	intrinsic component of membrane

tr|T1G4F6|T1G4F6_HELRO
Uncharacterized protein
Search

0.83	Vacuolar protein sorting-associated protein 28 homolog

0.81	GO:0032509	endosome transport via multivesicular body sorting pathway
0.79	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
0.78	GO:0045324	late endosome to vacuole transport
0.78	GO:0072666	establishment of protein localization to vacuole
0.66	GO:0006886	intracellular protein transport
0.40	GO:2000395	regulation of ubiquitin-dependent endocytosis
0.38	GO:0031397	negative regulation of protein ubiquitination
0.38	GO:0045807	positive regulation of endocytosis
0.38	GO:0051222	positive regulation of protein transport
0.38	GO:0045732	positive regulation of protein catabolic process

0.41	GO:0032403	protein complex binding
0.38	GO:0043130	ubiquitin binding

0.82	GO:0000813	ESCRT I complex
0.38	GO:0005769	early endosome
0.36	GO:0005829	cytosol
0.34	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1G4F7|T1G4F7_HELRO
Uncharacterized protein
Search

SLC18A2

0.81	Synaptic vesicular amine transporter

0.63	GO:0006855	drug transmembrane transport
0.52	GO:0015842	aminergic neurotransmitter loading into synaptic vesicle
0.51	GO:0015844	monoamine transport
0.47	GO:0015850	organic hydroxy compound transport
0.47	GO:0007626	locomotory behavior
0.46	GO:0015696	ammonium transport
0.46	GO:1904647	response to rotenone
0.46	GO:1904340	positive regulation of dopaminergic neuron differentiation
0.45	GO:0001975	response to amphetamine
0.43	GO:0009791	post-embryonic development

0.62	GO:0015238	drug transmembrane transporter activity
0.50	GO:0008504	monoamine transmembrane transporter activity
0.44	GO:1901618	organic hydroxy compound transmembrane transporter activity
0.43	GO:0005326	neurotransmitter transporter activity
0.43	GO:0008519	ammonium transmembrane transporter activity
0.34	GO:0005549	odorant binding
0.34	GO:0004984	olfactory receptor activity
0.33	GO:0005249	voltage-gated potassium channel activity
0.31	GO:0097159	organic cyclic compound binding

0.48	GO:0098793	presynapse
0.43	GO:0070382	exocytic vesicle
0.42	GO:0031594	neuromuscular junction
0.40	GO:0005887	integral component of plasma membrane
0.35	GO:0070081	clathrin-sculpted monoamine transport vesicle
0.35	GO:0030659	cytoplasmic vesicle membrane
0.35	GO:0042583	chromaffin granule
0.33	GO:0034705	potassium channel complex
0.33	GO:0098805	whole membrane
0.33	GO:0098588	bounding membrane of organelle

tr|T1G4F8|T1G4F8_HELRO
Uncharacterized protein
Search

0.59	F-box/LRR-repeat protein 7

0.62	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
0.55	GO:0016567	protein ubiquitination

0.55	GO:0004842	ubiquitin-protein transferase activity
0.54	GO:0003924	GTPase activity
0.53	GO:0032550	purine ribonucleoside binding
0.53	GO:0019001	guanyl nucleotide binding
0.45	GO:0032555	purine ribonucleotide binding
0.45	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0016874	ligase activity
0.39	GO:0003723	RNA binding

0.61

GO:0019005

SCF ubiquitin ligase complex

0.44	EC:6	GO:0016874
0.55	KEGG:R03876	GO:0004842

tr|T1G4G0|T1G4G0_HELRO
Uncharacterized protein
Search

0.56	Zinc finger MYM-type protein 1

0.68	GO:0046983	protein dimerization activity
0.38	GO:0008270	zinc ion binding

tr|T1G4G1|T1G4G1_HELRO
Uncharacterized protein
Search

0.53	GO:0055114	oxidation-reduction process
0.38	GO:0019369	arachidonic acid metabolic process
0.35	GO:0070836	caveola assembly

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.66	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.39	GO:0019825	oxygen binding
0.34	GO:0016758	transferase activity, transferring hexosyl groups

0.35	GO:0031984	organelle subcompartment
0.35	GO:0012505	endomembrane system
0.35	GO:0005901	caveola
0.34	GO:0031090	organelle membrane
0.34	GO:0044444	cytoplasmic part
0.34	GO:0043231	intracellular membrane-bounded organelle
0.32	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.68

GO:0016705

tr|T1G4G2|T1G4G2_HELRO
Uncharacterized protein
Search

0.28	Dihydropyridine sensitive L-type calcium channel

0.77	GO:0070588	calcium ion transmembrane transport
0.43	GO:0051924	regulation of calcium ion transport
0.43	GO:0003143	embryonic heart tube morphogenesis
0.43	GO:0007528	neuromuscular junction development
0.42	GO:2001257	regulation of cation channel activity
0.42	GO:0007268	chemical synaptic transmission
0.41	GO:0098912	membrane depolarization during atrial cardiac muscle cell action potential
0.41	GO:0086045	membrane depolarization during AV node cell action potential
0.40	GO:0086091	regulation of heart rate by cardiac conduction
0.39	GO:0070509	calcium ion import

0.82	GO:0005245	voltage-gated calcium channel activity
0.38	GO:0051015	actin filament binding
0.33	GO:0016301	kinase activity

0.81	GO:0005891	voltage-gated calcium channel complex
0.40	GO:0030315	T-tubule

tr|T1G4G3|T1G4G3_HELRO
Uncharacterized protein
Search

0.69	GO:0007596	blood coagulation
0.62	GO:0001775	cell activation
0.60	GO:0051258	protein polymerization
0.51	GO:0007165	signal transduction
0.46	GO:0048514	blood vessel morphogenesis
0.44	GO:0010519	negative regulation of phospholipase activity
0.44	GO:0051005	negative regulation of lipoprotein lipase activity
0.43	GO:0007155	cell adhesion
0.43	GO:0055091	phospholipid homeostasis
0.43	GO:0050996	positive regulation of lipid catabolic process

0.62	GO:0030674	protein binding, bridging
0.59	GO:0005102	receptor binding
0.43	GO:0004859	phospholipase inhibitor activity
0.42	GO:0005328	neurotransmitter:sodium symporter activity
0.41	GO:0050839	cell adhesion molecule binding
0.40	GO:0030545	receptor regulator activity
0.40	GO:0032403	protein complex binding
0.40	GO:0005509	calcium ion binding
0.39	GO:0070001	aspartic-type peptidase activity
0.38	GO:0004175	endopeptidase activity

0.67	GO:0005577	fibrinogen complex
0.41	GO:0005769	early endosome
0.40	GO:0031012	extracellular matrix
0.40	GO:0009986	cell surface
0.39	GO:0005794	Golgi apparatus
0.30	GO:0016020	membrane

tr|T1G4G4|T1G4G4_HELRO
Uncharacterized protein
Search

0.47	GO:0006508	proteolysis
0.46	GO:0070613	regulation of protein processing
0.43	GO:0006898	receptor-mediated endocytosis
0.40	GO:0030514	negative regulation of BMP signaling pathway
0.38	GO:0042730	fibrinolysis
0.38	GO:0048518	positive regulation of biological process
0.38	GO:0007275	multicellular organism development
0.38	GO:0048646	anatomical structure formation involved in morphogenesis
0.37	GO:0060429	epithelium development
0.37	GO:0003006	developmental process involved in reproduction

0.51	GO:0004252	serine-type endopeptidase activity
0.51	GO:0005509	calcium ion binding
0.46	GO:0001540	amyloid-beta binding
0.35	GO:0030492	hemoglobin binding
0.35	GO:0050750	low-density lipoprotein particle receptor binding
0.35	GO:0035258	steroid hormone receptor binding
0.35	GO:0030165	PDZ domain binding
0.34	GO:0042562	hormone binding
0.34	GO:0004872	receptor activity
0.34	GO:0017124	SH3 domain binding

0.39	GO:0005886	plasma membrane
0.37	GO:0005615	extracellular space
0.37	GO:0005794	Golgi apparatus
0.36	GO:0005903	brush border
0.36	GO:0030139	endocytic vesicle
0.36	GO:0005905	clathrin-coated pit
0.36	GO:0030425	dendrite
0.36	GO:0045177	apical part of cell
0.36	GO:0030424	axon
0.35	GO:0043235	receptor complex

0.51

GO:0004252

tr|T1G4G5|T1G4G5_HELRO
Glycerol-3-phosphate dehydrogenase [NAD(+)]
Search

0.68	NAD-dependent glycerol-3-phosphate dehydrogenase

0.79	GO:0046168	glycerol-3-phosphate catabolic process
0.60	GO:0005975	carbohydrate metabolic process
0.53	GO:0055114	oxidation-reduction process
0.42	GO:0006973	intracellular accumulation of glycerol
0.36	GO:0006564	L-serine biosynthetic process
0.35	GO:0016311	dephosphorylation
0.34	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation
0.34	GO:0007018	microtubule-based movement
0.34	GO:0006436	tryptophanyl-tRNA aminoacylation
0.34	GO:0006366	transcription by RNA polymerase II

0.79	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity
0.75	GO:0042803	protein homodimerization activity
0.68	GO:0051287	NAD binding
0.36	GO:0004647	phosphoserine phosphatase activity
0.36	GO:0004368	glycerol-3-phosphate dehydrogenase activity
0.35	GO:0000213	tRNA-intron endonuclease activity
0.34	GO:0003777	microtubule motor activity
0.34	GO:0008017	microtubule binding
0.34	GO:0004830	tryptophan-tRNA ligase activity
0.33	GO:0005524	ATP binding

0.76	GO:0009331	glycerol-3-phosphate dehydrogenase complex
0.33	GO:0009507	chloroplast
0.30	GO:0016020	membrane

0.79	EC:1.1.1.8 EC:1.1.1.94	GO:0004367
0.79	KEGG:R00842	GO:0004367

tr|T1G4G6|T1G4G6_HELRO
Uncharacterized protein
Search

PICH

0.77	Plk-interacting checkpoint helicase (Fragment)

0.62	GO:0004386	helicase activity
0.61	GO:0015616	DNA translocase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0016020

membrane

tr|T1G4G7|T1G4G7_HELRO
Uncharacterized protein
Search

0.74	MMP-1 protein (Fragment)

0.61	GO:0006508	proteolysis
0.51	GO:0006954	inflammatory response
0.43	GO:0060022	hard palate development
0.42	GO:0030574	collagen catabolic process
0.39	GO:0006928	movement of cell or subcellular component
0.39	GO:0001503	ossification
0.39	GO:0040011	locomotion
0.38	GO:0048731	system development
0.38	GO:0009653	anatomical structure morphogenesis
0.38	GO:0002376	immune system process

0.70	GO:0004222	metalloendopeptidase activity
0.63	GO:0008270	zinc ion binding
0.34	GO:0005518	collagen binding
0.34	GO:0001047	core promoter binding
0.34	GO:0004252	serine-type endopeptidase activity
0.33	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.33	GO:0005509	calcium ion binding
0.33	GO:0004930	G-protein coupled receptor activity
0.33	GO:0043565	sequence-specific DNA binding
0.33	GO:0016504	peptidase activator activity

0.74	GO:0031012	extracellular matrix
0.41	GO:0005615	extracellular space
0.36	GO:0005886	plasma membrane
0.35	GO:0042406	extrinsic component of endoplasmic reticulum membrane
0.34	GO:0031225	anchored component of membrane
0.33	GO:0005634	nucleus
0.33	GO:0035579	specific granule membrane
0.32	GO:0009986	cell surface
0.32	GO:0070013	intracellular organelle lumen
0.32	GO:0005581	collagen trimer

0.70	EC:3.4.24	GO:0004222
0.32	KEGG:R03532	GO:0004601

tr|T1G4G8|T1G4G8_HELRO
Uncharacterized protein
Search

0.67	GO:0001525	angiogenesis
0.65	GO:0043066	negative regulation of apoptotic process
0.62	GO:0007596	blood coagulation
0.56	GO:0001775	cell activation
0.55	GO:0051258	protein polymerization
0.49	GO:0051005	negative regulation of lipoprotein lipase activity
0.47	GO:2000351	regulation of endothelial cell apoptotic process
0.47	GO:0070328	triglyceride homeostasis
0.46	GO:0007154	cell communication
0.46	GO:0023052	signaling

0.57	GO:0030674	protein binding, bridging
0.52	GO:0005102	receptor binding
0.44	GO:0004857	enzyme inhibitor activity
0.43	GO:0042802	identical protein binding
0.39	GO:0005509	calcium ion binding
0.34	GO:0003723	RNA binding

0.68	GO:0005615	extracellular space
0.46	GO:0043234	protein complex
0.38	GO:0005578	proteinaceous extracellular matrix
0.30	GO:0016020	membrane

tr|T1G4G9|T1G4G9_HELRO
Uncharacterized protein
Search

0.71	Angiopoietin-related protein 4 (Fragment)

0.76	GO:0048514	blood vessel morphogenesis
0.73	GO:0043066	negative regulation of apoptotic process
0.70	GO:0048646	anatomical structure formation involved in morphogenesis
0.57	GO:0051005	negative regulation of lipoprotein lipase activity
0.55	GO:0070328	triglyceride homeostasis
0.51	GO:2000351	regulation of endothelial cell apoptotic process
0.46	GO:0019216	regulation of lipid metabolic process
0.45	GO:0010519	negative regulation of phospholipase activity
0.44	GO:0055091	phospholipid homeostasis
0.43	GO:0060840	artery development

0.50	GO:0004857	enzyme inhibitor activity
0.46	GO:0042802	identical protein binding
0.43	GO:0005178	integrin binding
0.41	GO:0008083	growth factor activity
0.37	GO:0008201	heparin binding
0.35	GO:0003723	RNA binding

0.69	GO:0005615	extracellular space
0.42	GO:0005578	proteinaceous extracellular matrix
0.42	GO:0005769	early endosome
0.41	GO:0009986	cell surface
0.40	GO:0005794	Golgi apparatus
0.37	GO:0030027	lamellipodium
0.30	GO:0016020	membrane

tr|T1G4H0|T1G4H0_HELRO
Uncharacterized protein
Search

0.38	Zinc finger protein (Fragment)

0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:0010468	regulation of gene expression

0.51	GO:0003676	nucleic acid binding
0.36	GO:0046872	metal ion binding

0.34

GO:0005634

nucleus

tr|T1G4H1|T1G4H1_HELRO
Uncharacterized protein
Search

0.54	Microfibril-associated glycoprotein 4

0.71	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.54	GO:0060216	definitive hemopoiesis
0.53	GO:0045747	positive regulation of Notch signaling pathway
0.53	GO:0002244	hematopoietic progenitor cell differentiation
0.51	GO:0001525	angiogenesis
0.41	GO:0007596	blood coagulation
0.39	GO:0007219	Notch signaling pathway
0.37	GO:0070897	DNA-templated transcriptional preinitiation complex assembly
0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.66	GO:0005102	receptor binding
0.37	GO:0017025	TBP-class protein binding
0.33	GO:0046872	metal ion binding

0.66	GO:0005615	extracellular space
0.38	GO:1903561	extracellular vesicle
0.30	GO:0016020	membrane

tr|T1G4H2|T1G4H2_HELRO
Uncharacterized protein
Search

0.51	Zinc finger domain-containing protein 16

0.75	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0060164	regulation of timing of neuron differentiation
0.55	GO:0021764	amygdala development
0.54	GO:0021960	anterior commissure morphogenesis
0.54	GO:0048712	negative regulation of astrocyte differentiation
0.54	GO:0002118	aggressive behavior

0.76	GO:0003707	steroid hormone receptor activity
0.65	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.51	GO:0042826	histone deacetylase binding
0.34	GO:0004046	aminoacylase activity
0.33	GO:0015631	tubulin binding
0.33	GO:0008237	metallopeptidase activity

0.61	GO:0005634	nucleus
0.33	GO:0070013	intracellular organelle lumen
0.32	GO:0044446	intracellular organelle part
0.32	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

0.34

EC:3.5.1.14

GO:0004046

tr|T1G4H3|T1G4H3_HELRO
Uncharacterized protein
Search

0.45

Tenascin

0.74	GO:0010519	negative regulation of phospholipase activity
0.73	GO:0051005	negative regulation of lipoprotein lipase activity
0.72	GO:0048514	blood vessel morphogenesis
0.72	GO:0055091	phospholipid homeostasis
0.70	GO:0050996	positive regulation of lipid catabolic process
0.70	GO:0070328	triglyceride homeostasis
0.68	GO:0060840	artery development
0.68	GO:0042632	cholesterol homeostasis
0.67	GO:0045766	positive regulation of angiogenesis
0.67	GO:0019915	lipid storage

0.70	GO:0004859	phospholipase inhibitor activity
0.68	GO:0005178	integrin binding
0.63	GO:0008083	growth factor activity
0.40	GO:0008201	heparin binding
0.38	GO:0001104	RNA polymerase II transcription cofactor activity
0.36	GO:0005509	calcium ion binding
0.35	GO:0003723	RNA binding

0.66	GO:0044421	extracellular region part
0.65	GO:0005769	early endosome
0.62	GO:0009986	cell surface
0.59	GO:0005794	Golgi apparatus
0.40	GO:0030027	lamellipodium
0.37	GO:0016592	mediator complex
0.30	GO:0016020	membrane

tr|T1G4H4|T1G4H4_HELRO
Uncharacterized protein
Search

0.54

Ficolin-1

0.75	GO:0001525	angiogenesis
0.72	GO:0043066	negative regulation of apoptotic process
0.54	GO:0051005	negative regulation of lipoprotein lipase activity
0.52	GO:0070328	triglyceride homeostasis
0.50	GO:2000351	regulation of endothelial cell apoptotic process
0.45	GO:0007596	blood coagulation
0.43	GO:0019216	regulation of lipid metabolic process
0.42	GO:0007155	cell adhesion
0.41	GO:0001666	response to hypoxia
0.40	GO:0051260	protein homooligomerization

0.48	GO:0004857	enzyme inhibitor activity
0.46	GO:0042802	identical protein binding
0.40	GO:0005509	calcium ion binding
0.38	GO:0005178	integrin binding
0.38	GO:0042302	structural constituent of cuticle
0.38	GO:0008083	growth factor activity
0.36	GO:0030674	protein binding, bridging
0.35	GO:0003723	RNA binding

0.69	GO:0005615	extracellular space
0.40	GO:0005578	proteinaceous extracellular matrix
0.38	GO:0005769	early endosome
0.37	GO:0009986	cell surface
0.36	GO:0005794	Golgi apparatus
0.34	GO:0043234	protein complex
0.30	GO:0016020	membrane

tr|T1G4H5|T1G4H5_HELRO
Uncharacterized protein
Search

0.48	Microfibril associated protein 4

0.75	GO:0001525	angiogenesis
0.72	GO:0043066	negative regulation of apoptotic process
0.53	GO:0051005	negative regulation of lipoprotein lipase activity
0.51	GO:0070328	triglyceride homeostasis
0.50	GO:2000351	regulation of endothelial cell apoptotic process
0.44	GO:0007596	blood coagulation
0.42	GO:0019216	regulation of lipid metabolic process
0.42	GO:0007155	cell adhesion
0.41	GO:0001666	response to hypoxia
0.40	GO:0051260	protein homooligomerization

0.48	GO:0004857	enzyme inhibitor activity
0.45	GO:0042802	identical protein binding
0.40	GO:0005509	calcium ion binding
0.38	GO:0005178	integrin binding
0.37	GO:0042302	structural constituent of cuticle
0.37	GO:0008083	growth factor activity
0.36	GO:0030674	protein binding, bridging
0.35	GO:0003723	RNA binding

0.69	GO:0005615	extracellular space
0.39	GO:0005578	proteinaceous extracellular matrix
0.38	GO:0005769	early endosome
0.37	GO:0009986	cell surface
0.36	GO:0005794	Golgi apparatus
0.34	GO:0043234	protein complex
0.30	GO:0016020	membrane

tr|T1G4H6|T1G4H6_HELRO
Uncharacterized protein
Search

0.50

Tenascin

0.76	GO:0001525	angiogenesis
0.73	GO:0043066	negative regulation of apoptotic process
0.55	GO:0051005	negative regulation of lipoprotein lipase activity
0.53	GO:0070328	triglyceride homeostasis
0.51	GO:2000351	regulation of endothelial cell apoptotic process
0.45	GO:0007596	blood coagulation
0.43	GO:0019216	regulation of lipid metabolic process
0.42	GO:0007155	cell adhesion
0.41	GO:0001666	response to hypoxia
0.40	GO:0051260	protein homooligomerization

0.49	GO:0004857	enzyme inhibitor activity
0.46	GO:0042802	identical protein binding
0.40	GO:0005509	calcium ion binding
0.38	GO:0005102	receptor binding
0.38	GO:0050839	cell adhesion molecule binding
0.37	GO:0001104	RNA polymerase II transcription cofactor activity
0.37	GO:0030545	receptor regulator activity
0.37	GO:0032403	protein complex binding
0.36	GO:0030674	protein binding, bridging
0.35	GO:0003723	RNA binding

0.69	GO:0005615	extracellular space
0.40	GO:0005578	proteinaceous extracellular matrix
0.38	GO:0005769	early endosome
0.37	GO:0016592	mediator complex
0.37	GO:0009986	cell surface
0.36	GO:0005794	Golgi apparatus
0.35	GO:0030906	retromer, cargo-selective complex
0.34	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

tr|T1G4H7|T1G4H7_HELRO
Uncharacterized protein
Search

0.11

Tenascin

0.59	GO:0007596	blood coagulation
0.57	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.49	GO:0072376	protein activation cascade
0.48	GO:0001775	cell activation
0.47	GO:0051258	protein polymerization
0.43	GO:0006357	regulation of transcription by RNA polymerase II
0.41	GO:0007165	signal transduction
0.39	GO:0006351	transcription, DNA-templated

0.52	GO:0005509	calcium ion binding
0.48	GO:0030674	protein binding, bridging
0.46	GO:0001104	RNA polymerase II transcription cofactor activity
0.45	GO:0005102	receptor binding

0.51	GO:0005577	fibrinogen complex
0.46	GO:0016592	mediator complex
0.30	GO:0016020	membrane

tr|T1G4H8|T1G4H8_HELRO
Uncharacterized protein
Search

0.11	Histone-lysine N-methyltransferase MLL4 (Fragment)

0.75	GO:0034968	histone lysine methylation
0.57	GO:0051569	regulation of histone H3-K4 methylation
0.56	GO:0018023	peptidyl-lysine trimethylation
0.55	GO:0007611	learning or memory
0.54	GO:0048511	rhythmic process
0.52	GO:0030728	ovulation
0.51	GO:0048513	animal organ development
0.51	GO:2001141	regulation of RNA biosynthetic process
0.51	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.50	GO:0010468	regulation of gene expression

0.75	GO:0018024	histone-lysine N-methyltransferase activity
0.59	GO:0008270	zinc ion binding
0.52	GO:0003677	DNA binding
0.47	GO:0070577	lysine-acetylated histone binding
0.44	GO:0003682	chromatin binding
0.44	GO:0001067	regulatory region nucleic acid binding
0.44	GO:0042803	protein homodimerization activity
0.41	GO:0003700	DNA binding transcription factor activity
0.34	GO:0005199	structural constituent of cell wall

0.67	GO:0035097	histone methyltransferase complex
0.42	GO:0005829	cytosol
0.33	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.75

GO:0018024

tr|T1G4H9|T1G4H9_HELRO
Uncharacterized protein
Search

0.76	GO:0001737	establishment of imaginal disc-derived wing hair orientation
0.74	GO:0042067	establishment of ommatidial planar polarity
0.44	GO:0016567	protein ubiquitination
0.43	GO:0034968	histone lysine methylation
0.43	GO:0060071	Wnt signaling pathway, planar cell polarity pathway
0.42	GO:0030318	melanocyte differentiation
0.42	GO:0002090	regulation of receptor internalization
0.41	GO:0031398	positive regulation of protein ubiquitination
0.38	GO:0070588	calcium ion transmembrane transport
0.37	GO:0016042	lipid catabolic process

0.45	GO:0002039	p53 binding
0.45	GO:0004842	ubiquitin-protein transferase activity
0.44	GO:0018024	histone-lysine N-methyltransferase activity
0.43	GO:0008270	zinc ion binding
0.42	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.40	GO:0042803	protein homodimerization activity
0.38	GO:0005262	calcium channel activity
0.38	GO:0031625	ubiquitin protein ligase binding
0.37	GO:0005096	GTPase activator activity
0.37	GO:0004674	protein serine/threonine kinase activity

0.42	GO:0000151	ubiquitin ligase complex
0.40	GO:0048471	perinuclear region of cytoplasm
0.40	GO:0005694	chromosome
0.40	GO:0005634	nucleus
0.39	GO:0031410	cytoplasmic vesicle
0.39	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.44	EC:2.1.1.43	GO:0018024
0.45	KEGG:R03876	GO:0004842

tr|T1G4I0|T1G4I0_HELRO
Uncharacterized protein
Search

0.64	Hemerythrin

0.63

GO:0005506

iron ion binding

tr|T1G4I1|T1G4I1_HELRO
Uncharacterized protein
Search

tr|T1G4I2|T1G4I2_HELRO
Aminomethyltransferase
Search

AMT

0.54	Aminomethyltransferase, mitochondrial

0.75	GO:0006546	glycine catabolic process
0.62	GO:0032259	methylation
0.35	GO:0006730	one-carbon metabolic process
0.33	GO:0055114	oxidation-reduction process

0.79	GO:0004047	aminomethyltransferase activity
0.67	GO:0008483	transaminase activity
0.35	GO:0031405	lipoic acid binding
0.35	GO:0016642	oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor

0.58	GO:0005739	mitochondrion
0.46	GO:0005654	nucleoplasm
0.33	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

0.79

EC:2.1.2.10

GO:0004047

tr|T1G4I3|T1G4I3_HELRO
Uncharacterized protein
Search

CTGF

0.86	Connective tissue growth factor XCTGF

0.79	GO:0001558	regulation of cell growth
0.56	GO:0035988	chondrocyte proliferation
0.56	GO:0001502	cartilage condensation
0.55	GO:0051496	positive regulation of stress fiber assembly
0.55	GO:0032330	regulation of chondrocyte differentiation
0.54	GO:0046330	positive regulation of JNK cascade
0.53	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.53	GO:0030324	lung development
0.53	GO:0008543	fibroblast growth factor receptor signaling pathway
0.53	GO:0001894	tissue homeostasis

0.84	GO:0005520	insulin-like growth factor binding
0.58	GO:0005178	integrin binding
0.56	GO:0008201	heparin binding
0.53	GO:0008022	protein C-terminus binding
0.40	GO:0008083	growth factor activity
0.40	GO:0001968	fibronectin binding
0.37	GO:0005112	Notch binding

0.66	GO:0005576	extracellular region
0.39	GO:0005801	cis-Golgi network
0.38	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0005938	cell cortex
0.37	GO:0005921	gap junction
0.36	GO:0005829	cytosol
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1G4I4|T1G4I4_HELRO
Uncharacterized protein
Search

0.10	Ubiquitin-associated protein 2-like (Fragment)

0.76	GO:0061484	hematopoietic stem cell homeostasis
0.65	GO:0010628	positive regulation of gene expression
0.55	GO:0007339	binding of sperm to zona pellucida

0.59	GO:0005634	nucleus
0.50	GO:1902493	acetyltransferase complex
0.46	GO:0031974	membrane-enclosed lumen
0.46	GO:0005737	cytoplasm
0.43	GO:0043234	protein complex
0.42	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

tr|T1G4I5|T1G4I5_HELRO
Stathmin
Search

0.64

Stathmin

0.84

GO:0031110

regulation of microtubule polymerization or depolymerization

tr|T1G4I6|T1G4I6_HELRO
Uncharacterized protein
Search

SPAG6

0.94	sperm-associated antigen 6

0.51	GO:0007288	sperm axoneme assembly
0.51	GO:0021591	ventricular system development

0.36

GO:0005515

protein binding

0.68	GO:0015630	microtubule cytoskeleton
0.53	GO:1990716	axonemal central apparatus
0.51	GO:0097228	sperm principal piece
0.41	GO:0099513	polymeric cytoskeletal fiber
0.38	GO:0005634	nucleus

tr|T1G4I7|T1G4I7_HELRO
Uncharacterized protein
Search

0.61	Myohemerythrin

0.39	GO:0015671	oxygen transport
0.34	GO:0046686	response to cadmium ion
0.33	GO:0035940	negative regulation of peptidase activity in other organism
0.33	GO:0035899	negative regulation of blood coagulation in other organism
0.33	GO:0007596	blood coagulation

0.63	GO:0005506	iron ion binding
0.40	GO:0005344	oxygen carrier activity
0.32	GO:0030414	peptidase inhibitor activity

0.32	GO:0005576	extracellular region
0.32	GO:0005737	cytoplasm

tr|T1G4I8|T1G4I8_HELRO
Uncharacterized protein
Search

0.57	GO:0007219	Notch signaling pathway
0.53	GO:0007275	multicellular organism development
0.53	GO:0030154	cell differentiation
0.50	GO:0050793	regulation of developmental process
0.47	GO:0007155	cell adhesion
0.41	GO:0051239	regulation of multicellular organismal process
0.41	GO:0030199	collagen fibril organization
0.41	GO:0043506	regulation of JUN kinase activity
0.40	GO:0006641	triglyceride metabolic process
0.39	GO:0050919	negative chemotaxis

0.61	GO:0005509	calcium ion binding
0.41	GO:0005112	Notch binding
0.40	GO:0005518	collagen binding
0.40	GO:0008201	heparin binding
0.40	GO:0048495	Roundabout binding
0.39	GO:0008270	zinc ion binding
0.37	GO:0003944	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase activity
0.36	GO:0016158	3-phytase activity
0.36	GO:0140096	catalytic activity, acting on a protein
0.35	GO:0005201	extracellular matrix structural constituent

0.45	GO:0005578	proteinaceous extracellular matrix
0.40	GO:0005615	extracellular space
0.33	GO:0005622	intracellular
0.30	GO:0016020	membrane

0.37

EC:3.1.4.45

GO:0003944

tr|T1G4I9|T1G4I9_HELRO
Uncharacterized protein
Search

0.67	Proprotein convertase subtilisin/kexin type 7 (Fragment)

0.61	GO:0006508	proteolysis
0.49	GO:0051604	protein maturation
0.44	GO:0048840	otolith development
0.42	GO:0001654	eye development
0.42	GO:0043009	chordate embryonic development
0.42	GO:0007420	brain development
0.34	GO:0042445	hormone metabolic process
0.33	GO:0010951	negative regulation of endopeptidase activity
0.33	GO:0006518	peptide metabolic process

0.69	GO:0004252	serine-type endopeptidase activity
0.34	GO:0004867	serine-type endopeptidase inhibitor activity
0.33	GO:0005515	protein binding
0.32	GO:0046872	metal ion binding

0.50	GO:0030173	integral component of Golgi membrane
0.42	GO:0005802	trans-Golgi network
0.34	GO:0005788	endoplasmic reticulum lumen

0.69

GO:0004252

tr|T1G4J0|T1G4J0_HELRO
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
Search

CDIPT

0.68	CDP-diacylglycerol--inositol 3-phosphatidyltransferase

0.68	GO:0008654	phospholipid biosynthetic process
0.46	GO:0046488	phosphatidylinositol metabolic process
0.46	GO:0045017	glycerolipid biosynthetic process
0.44	GO:0071788	endoplasmic reticulum tubular network maintenance
0.43	GO:0072576	liver morphogenesis
0.43	GO:0060729	intestinal epithelial structure maintenance
0.43	GO:0060219	camera-type eye photoreceptor cell differentiation
0.43	GO:0010842	retina layer formation
0.42	GO:0002088	lens development in camera-type eye
0.41	GO:0034976	response to endoplasmic reticulum stress

0.80	GO:0003881	CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity
0.36	GO:0019992	diacylglycerol binding
0.36	GO:0043178	alcohol binding
0.35	GO:0030145	manganese ion binding
0.34	GO:0030246	carbohydrate binding
0.34	GO:0008444	CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity
0.33	GO:0003676	nucleic acid binding

0.66	GO:0005794	Golgi apparatus
0.36	GO:0098588	bounding membrane of organelle
0.35	GO:0098805	whole membrane
0.35	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0019867	outer membrane
0.34	GO:0031966	mitochondrial membrane
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.80	EC:2.7.8.11	GO:0003881
0.80	KEGG:R01802	GO:0003881

tr|T1G4J1|T1G4J1_HELRO
Uncharacterized protein
Search

0.67	Hemerythrin

0.36	GO:0046686	response to cadmium ion
0.35	GO:0015671	oxygen transport

0.63	GO:0005506	iron ion binding
0.35	GO:0005344	oxygen carrier activity

tr|T1G4J2|T1G4J2_HELRO
Uncharacterized protein
Search

PDCL

0.21	Thioredoxin

0.60	GO:0008616	queuosine biosynthetic process
0.52	GO:1902605	heterotrimeric G-protein complex assembly
0.46	GO:0007601	visual perception

0.64

GO:0008479

queuine tRNA-ribosyltransferase activity

0.44	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.64

EC:2.4.2.29

GO:0008479

tr|T1G4J3|T1G4J3_HELRO
Cytosolic Fe-S cluster assembly factor NUBP1 homolog
Search

NBP35

0.50	ATP-binding cassette transporter

0.72	GO:0016226	iron-sulfur cluster assembly
0.55	GO:0002098	tRNA wobble uridine modification
0.39	GO:0072697	protein localization to cell cortex
0.39	GO:0051642	centrosome localization
0.39	GO:0010826	negative regulation of centrosome duplication
0.38	GO:0016049	cell growth
0.37	GO:0006879	cellular iron ion homeostasis
0.36	GO:0097193	intrinsic apoptotic signaling pathway
0.34	GO:0051013	microtubule severing
0.33	GO:0006464	cellular protein modification process

0.66	GO:0051539	4 iron, 4 sulfur cluster binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0046872	metal ion binding
0.47	GO:0016887	ATPase activity
0.35	GO:0008641	ubiquitin-like modifier activating enzyme activity
0.34	GO:0008017	microtubule binding
0.33	GO:0003684	damaged DNA binding

0.63	GO:1904564	Nbp35-Cfd1 ATPase complex
0.47	GO:0005634	nucleus
0.34	GO:0005886	plasma membrane
0.34	GO:0000922	spindle pole
0.34	GO:0005813	centrosome
0.33	GO:0005874	microtubule

0.47

GO:0016887

tr|T1G4J4|T1G4J4_HELRO
Uncharacterized protein
Search

0.66	Myohemerythrin

0.38	GO:0015671	oxygen transport
0.35	GO:0035940	negative regulation of peptidase activity in other organism
0.35	GO:0035899	negative regulation of blood coagulation in other organism
0.34	GO:0007596	blood coagulation

0.63	GO:0005506	iron ion binding
0.39	GO:0005344	oxygen carrier activity
0.34	GO:0030414	peptidase inhibitor activity

0.33

GO:0005576

extracellular region

tr|T1G4J5|T1G4J5_HELRO
Uncharacterized protein
Search

0.55	REPTOR-binding partner, isoform C

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.43	GO:0038202	TORC1 signaling
0.43	GO:0044246	regulation of multicellular organismal metabolic process
0.42	GO:0051254	positive regulation of RNA metabolic process
0.42	GO:0010557	positive regulation of macromolecule biosynthetic process
0.42	GO:0031328	positive regulation of cellular biosynthetic process
0.41	GO:0042594	response to starvation
0.40	GO:0046326	positive regulation of glucose import

0.61	GO:0003700	DNA binding transcription factor activity
0.41	GO:0003682	chromatin binding
0.40	GO:0042803	protein homodimerization activity
0.40	GO:0046982	protein heterodimerization activity
0.35	GO:0003677	DNA binding

0.39	GO:0005634	nucleus
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

tr|T1G4J6|T1G4J6_HELRO
Uncharacterized protein
Search

RABGEF1

0.89	RAB guanine nucleotide exchange factor (GEF) 1

0.41	GO:1900234	regulation of Kit signaling pathway
0.40	GO:0060368	regulation of Fc receptor mediated stimulatory signaling pathway
0.40	GO:0043305	negative regulation of mast cell degranulation
0.40	GO:1900165	negative regulation of interleukin-6 secretion
0.40	GO:0048261	negative regulation of receptor-mediated endocytosis
0.39	GO:0002686	negative regulation of leukocyte migration
0.39	GO:0050728	negative regulation of inflammatory response
0.39	GO:0046580	negative regulation of Ras protein signal transduction
0.37	GO:0006612	protein targeting to membrane
0.37	GO:0001933	negative regulation of protein phosphorylation

0.61	GO:0008270	zinc ion binding
0.53	GO:0003677	DNA binding
0.39	GO:0017112	Rab guanyl-nucleotide exchange factor activity
0.38	GO:0061630	ubiquitin protein ligase activity

0.39	GO:0005769	early endosome
0.38	GO:0005730	nucleolus
0.37	GO:0005829	cytosol
0.37	GO:0055037	recycling endosome
0.30	GO:0016021	integral component of membrane

tr|T1G4J7|T1G4J7_HELRO
Uncharacterized protein
Search

0.64	Hemerythrin

0.63

GO:0005506

iron ion binding

tr|T1G4J8|T1G4J8_HELRO
Uncharacterized protein
Search

0.66	GO:0007219	Notch signaling pathway
0.58	GO:0007275	multicellular organism development
0.57	GO:0030154	cell differentiation
0.55	GO:0050793	regulation of developmental process
0.45	GO:0097150	neuronal stem cell population maintenance
0.45	GO:0035172	hemocyte proliferation
0.45	GO:0009888	tissue development
0.45	GO:0009653	anatomical structure morphogenesis
0.45	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin
0.44	GO:0060250	germ-line stem-cell niche homeostasis

0.70	GO:0005509	calcium ion binding
0.46	GO:0004872	receptor activity
0.42	GO:0005112	Notch binding
0.41	GO:0003682	chromatin binding
0.36	GO:0008061	chitin binding
0.36	GO:0005201	extracellular matrix structural constituent
0.36	GO:0019828	aspartic-type endopeptidase inhibitor activity
0.35	GO:0004222	metalloendopeptidase activity
0.35	GO:0019899	enzyme binding
0.34	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding

0.44	GO:0035003	subapical complex
0.43	GO:0009986	cell surface
0.42	GO:0030139	endocytic vesicle
0.42	GO:0005912	adherens junction
0.42	GO:0005770	late endosome
0.41	GO:0005764	lysosome
0.39	GO:0005634	nucleus
0.38	GO:0043234	protein complex
0.37	GO:0043235	receptor complex
0.36	GO:0005576	extracellular region

0.35

GO:0004222

tr|T1G4J9|T1G4J9_HELRO
Phosphatidylethanolamine N-methyltransferase
Search

PEMT

0.64	Phosphatidyl-N-methylethanolamine N-methyltransferase

0.84	GO:0006656	phosphatidylcholine biosynthetic process
0.63	GO:0032259	methylation
0.48	GO:0006686	sphingomyelin biosynthetic process
0.46	GO:1903955	positive regulation of protein targeting to mitochondrion
0.36	GO:0050747	positive regulation of lipoprotein metabolic process
0.35	GO:0033273	response to vitamin
0.35	GO:0045471	response to ethanol
0.35	GO:0043200	response to amino acid
0.35	GO:0008285	negative regulation of cell proliferation
0.34	GO:0046498	S-adenosylhomocysteine metabolic process

0.85	GO:0080101	phosphatidyl-N-dimethylethanolamine N-methyltransferase activity
0.85	GO:0000773	phosphatidyl-N-methylethanolamine N-methyltransferase activity
0.59	GO:0004608	phosphatidylethanolamine N-methyltransferase activity
0.35	GO:0008429	phosphatidylethanolamine binding
0.35	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors
0.34	GO:0004481	methylene-fatty-acyl-phospholipid synthase activity
0.33	GO:0043531	ADP binding
0.33	GO:0004252	serine-type endopeptidase activity

0.70	GO:0005789	endoplasmic reticulum membrane
0.61	GO:0031966	mitochondrial membrane
0.35	GO:0031526	brush border membrane
0.35	GO:0042383	sarcolemma
0.30	GO:0016021	integral component of membrane

0.85	EC:2.1.1.71	GO:0080101
0.85	KEGG:R01320	GO:0080101

tr|T1G4K0|T1G4K0_HELRO
Uncharacterized protein
Search

0.96	Hormonally up-regulated neu tumor-associated kinase (Fragment)

0.63	GO:0006468	protein phosphorylation
0.41	GO:0035556	intracellular signal transduction
0.33	GO:0007275	multicellular organism development
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005515	protein binding
0.32	GO:0003735	structural constituent of ribosome

0.40	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.32	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

tr|T1G4K1|T1G4K1_HELRO
Uncharacterized protein
Search

0.61	GO:0007165	signal transduction
0.45	GO:0048790	maintenance of presynaptic active zone structure
0.45	GO:0048789	cytoskeletal matrix organization at active zone
0.45	GO:0045467	R7 cell development
0.44	GO:1902284	neuron projection extension involved in neuron projection guidance
0.44	GO:0048675	axon extension
0.43	GO:0097479	synaptic vesicle localization
0.42	GO:0007411	axon guidance
0.38	GO:0043087	regulation of GTPase activity
0.37	GO:0051345	positive regulation of hydrolase activity

0.37	GO:0005096	GTPase activator activity
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0032561	guanyl ribonucleotide binding
0.32	GO:0046872	metal ion binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003676	nucleic acid binding

0.43	GO:0048786	presynaptic active zone
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|T1G4K2|T1G4K2_HELRO
Uncharacterized protein
Search

DRD1

0.92	Dopamine receptor 1

0.80	GO:0007212	dopamine receptor signaling pathway
0.78	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.70	GO:0042311	vasodilation
0.61	GO:0071870	cellular response to catecholamine stimulus
0.60	GO:0046960	sensitization
0.59	GO:0060359	response to ammonium ion
0.58	GO:0060292	long term synaptic depression
0.58	GO:0001975	response to amphetamine
0.57	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.56	GO:0072347	response to anesthetic

0.82	GO:0004952	dopamine neurotransmitter receptor activity
0.61	GO:0035240	dopamine binding
0.41	GO:0008227	G-protein coupled amine receptor activity
0.39	GO:0099528	G-protein coupled neurotransmitter receptor activity
0.39	GO:0015464	acetylcholine receptor activity
0.35	GO:0051378	serotonin binding
0.35	GO:0099589	serotonin receptor activity
0.35	GO:0031750	D3 dopamine receptor binding
0.35	GO:0031701	angiotensin receptor binding
0.34	GO:0001965	G-protein alpha-subunit binding

0.64	GO:0005887	integral component of plasma membrane
0.59	GO:0060170	ciliary membrane
0.57	GO:0097730	non-motile cilium
0.46	GO:0005783	endoplasmic reticulum
0.45	GO:0031526	brush border membrane
0.42	GO:0005634	nucleus
0.39	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.38	GO:0031984	organelle subcompartment
0.35	GO:0044326	dendritic spine neck
0.35	GO:0044327	dendritic spine head

tr|T1G4K3|T1G4K3_HELRO
Uncharacterized protein
Search

0.76	GO:0034968	histone lysine methylation
0.52	GO:2001141	regulation of RNA biosynthetic process
0.52	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.52	GO:0010468	regulation of gene expression
0.52	GO:1901674	regulation of histone H3-K27 acetylation
0.51	GO:2001040	positive regulation of cellular response to drug
0.51	GO:0006351	transcription, DNA-templated
0.51	GO:0030097	hemopoiesis
0.50	GO:0048172	regulation of short-term neuronal synaptic plasticity
0.50	GO:0043984	histone H4-K16 acetylation

0.76	GO:0018024	histone-lysine N-methyltransferase activity
0.58	GO:0008270	zinc ion binding
0.51	GO:0003677	DNA binding
0.49	GO:0070577	lysine-acetylated histone binding
0.46	GO:0001067	regulatory region nucleic acid binding
0.46	GO:0003682	chromatin binding
0.46	GO:0042803	protein homodimerization activity
0.43	GO:0003700	DNA binding transcription factor activity
0.34	GO:0034450	ubiquitin-ubiquitin ligase activity
0.34	GO:0005199	structural constituent of cell wall

0.70	GO:0035097	histone methyltransferase complex
0.44	GO:0005829	cytosol
0.35	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
0.34	GO:0000151	ubiquitin ligase complex

0.76

GO:0018024

tr|T1G4K4|T1G4K4_HELRO
Uncharacterized protein
Search

0.46	Glycogen synthase kinase-3 beta

0.63	GO:0006468	protein phosphorylation
0.38	GO:0019953	sexual reproduction
0.36	GO:0048609	multicellular organismal reproductive process
0.36	GO:0071472	cellular response to salt stress
0.36	GO:0022413	reproductive process in single-celled organism
0.36	GO:0018209	peptidyl-serine modification
0.36	GO:0034605	cellular response to heat
0.36	GO:0006303	double-strand break repair via nonhomologous end joining
0.35	GO:0000070	mitotic sister chromatid segregation
0.35	GO:1903046	meiotic cell cycle process

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0030332	cyclin binding
0.35	GO:0030234	enzyme regulator activity
0.33	GO:0008171	O-methyltransferase activity
0.32	GO:0060089	molecular transducer activity

0.32	GO:0005634	nucleus
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.33

GO:0008171

tr|T1G4K5|T1G4K5_HELRO
Polypeptide N-acetylgalactosaminyltransferase
Search

0.65	Polypeptide N-acetylgalactosaminyltransferase

0.73	GO:0043413	macromolecule glycosylation
0.73	GO:0009101	glycoprotein biosynthetic process
0.59	GO:0006464	cellular protein modification process
0.42	GO:0032504	multicellular organism reproduction

0.68	GO:0030246	carbohydrate binding
0.64	GO:0016757	transferase activity, transferring glycosyl groups
0.34	GO:0140096	catalytic activity, acting on a protein
0.32	GO:0046872	metal ion binding

0.71	GO:0000139	Golgi membrane
0.43	GO:0031985	Golgi cisterna
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.64

GO:0016757

tr|T1G4K6|T1G4K6_HELRO
Uncharacterized protein
Search

CHP1

0.47	Ethanol sensitive with low memory

0.46	GO:0032417	positive regulation of sodium:proton antiporter activity
0.46	GO:0070885	negative regulation of calcineurin-NFAT signaling cascade
0.44	GO:0042308	negative regulation of protein import into nucleus
0.44	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.43	GO:0051453	regulation of intracellular pH
0.43	GO:1901214	regulation of neuron death
0.43	GO:0010923	negative regulation of phosphatase activity
0.38	GO:0060050	positive regulation of protein glycosylation
0.38	GO:0031953	negative regulation of protein autophosphorylation
0.38	GO:0006611	protein export from nucleus

0.70	GO:0005509	calcium ion binding
0.44	GO:0048306	calcium-dependent protein binding
0.36	GO:0019900	kinase binding
0.36	GO:0004860	protein kinase inhibitor activity
0.36	GO:0008017	microtubule binding
0.34	GO:0016174	NAD(P)H oxidase activity
0.34	GO:0005215	transporter activity

0.37	GO:0005886	plasma membrane
0.36	GO:0030133	transport vesicle
0.36	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.36	GO:0000139	Golgi membrane
0.36	GO:0015630	microtubule cytoskeleton
0.36	GO:0005783	endoplasmic reticulum
0.35	GO:0005829	cytosol
0.34	GO:0005634	nucleus
0.34	GO:0005925	focal adhesion
0.34	GO:0070062	extracellular exosome

0.34

EC:1.6.3.1

GO:0016174

tr|T1G4K7|T1G4K7_HELRO
Uncharacterized protein
Search

0.63	mitogen-activated protein kinase kinase kinase 10

0.67	GO:0000186	activation of MAPKK activity
0.65	GO:0043507	positive regulation of JUN kinase activity
0.65	GO:0007254	JNK cascade
0.53	GO:0000187	activation of MAPK activity
0.47	GO:0018107	peptidyl-threonine phosphorylation
0.47	GO:0046777	protein autophosphorylation
0.47	GO:0043433	negative regulation of DNA binding transcription factor activity
0.47	GO:0007224	smoothened signaling pathway
0.47	GO:0018105	peptidyl-serine phosphorylation
0.46	GO:0008283	cell proliferation

0.68	GO:0004709	MAP kinase kinase kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0031435	mitogen-activated protein kinase kinase kinase binding
0.49	GO:0043425	bHLH transcription factor binding
0.46	GO:0003714	transcription corepressor activity
0.45	GO:0042803	protein homodimerization activity
0.39	GO:0048365	Rac GTPase binding
0.39	GO:0031434	mitogen-activated protein kinase kinase binding

0.46	GO:0005813	centrosome
0.44	GO:0005874	microtubule
0.38	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.68

EC:2.7.11 EC:2.7.11.25

GO:0004709

tr|T1G4K8|T1G4K8_HELRO
Uncharacterized protein
Search

0.64	GO:0097264	self proteolysis
0.60	GO:0048666	neuron development
0.46	GO:0007165	signal transduction
0.39	GO:0000902	cell morphogenesis
0.38	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.38	GO:0032990	cell part morphogenesis
0.37	GO:0120036	plasma membrane bounded cell projection organization
0.37	GO:0006935	chemotaxis
0.36	GO:0006928	movement of cell or subcellular component
0.35	GO:0018108	peptidyl-tyrosine phosphorylation

0.38	GO:0003944	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase activity
0.37	GO:0050839	cell adhesion molecule binding
0.37	GO:0005509	calcium ion binding
0.37	GO:0042803	protein homodimerization activity
0.37	GO:0046982	protein heterodimerization activity
0.36	GO:0004714	transmembrane receptor protein tyrosine kinase activity

0.38	GO:0005887	integral component of plasma membrane
0.37	GO:0043005	neuron projection

0.38

EC:3.1.4.45

GO:0003944

tr|T1G4K9|T1G4K9_HELRO
Terpene cyclase/mutase family member
Search

LSS

0.69	Terpene cyclase/mutase family member

0.52	GO:0006695	cholesterol biosynthetic process
0.49	GO:0031647	regulation of protein stability

0.66

GO:0016866

intramolecular transferase activity

0.50	GO:0005811	lipid droplet
0.30	GO:0044425	membrane part

0.66

EC:5.4

GO:0016866

tr|T1G4L0|T1G4L0_HELRO
Uncharacterized protein
Search

RABIF

0.90	RAB interacting factor

0.77	GO:0007264	small GTPase mediated signal transduction
0.66	GO:0065009	regulation of molecular function
0.46	GO:0006892	post-Golgi vesicle-mediated transport
0.37	GO:0000956	nuclear-transcribed mRNA catabolic process
0.37	GO:0000398	mRNA splicing, via spliceosome
0.35	GO:0015031	protein transport
0.34	GO:0006357	regulation of transcription by RNA polymerase II
0.34	GO:0061025	membrane fusion

0.75	GO:0005085	guanyl-nucleotide exchange factor activity
0.45	GO:0008270	zinc ion binding
0.35	GO:0001104	RNA polymerase II transcription cofactor activity
0.34	GO:0008080	N-acetyltransferase activity
0.32	GO:0003677	DNA binding

0.45	GO:0005622	intracellular
0.34	GO:1990904	ribonucleoprotein complex
0.34	GO:0043233	organelle lumen
0.34	GO:0043227	membrane-bounded organelle
0.33	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.34

GO:0008080

tr|T1G4L1|T1G4L1_HELRO
Uncharacterized protein
Search

IFT46

0.95	Intraflagellar transport protein 46

0.84	GO:0042073	intraciliary transport
0.54	GO:0060271	cilium assembly
0.52	GO:0007224	smoothened signaling pathway
0.36	GO:0031647	regulation of protein stability
0.35	GO:0048264	determination of ventral identity
0.35	GO:0060285	cilium-dependent cell motility
0.35	GO:0048793	pronephros development
0.35	GO:1902017	regulation of cilium assembly
0.34	GO:0060041	retina development in camera-type eye
0.34	GO:0001578	microtubule bundle formation

0.34

GO:0008022

protein C-terminus binding

0.77	GO:0005929	cilium
0.56	GO:0030992	intraciliary transport particle B
0.53	GO:0005813	centrosome
0.38	GO:0005737	cytoplasm
0.36	GO:0120038	plasma membrane bounded cell projection part
0.34	GO:0098590	plasma membrane region
0.33	GO:0098588	bounding membrane of organelle
0.30	GO:0031224	intrinsic component of membrane

tr|T1G4L2|T1G4L2_HELRO
Uncharacterized protein
Search

0.62	Steroid-5-alpha-reductase alpha polypeptide 1

0.67	GO:0008202	steroid metabolic process
0.53	GO:0055114	oxidation-reduction process
0.44	GO:0030540	female genitalia development
0.43	GO:0030539	male genitalia development
0.41	GO:0034754	cellular hormone metabolic process
0.41	GO:0042446	hormone biosynthetic process
0.40	GO:0008610	lipid biosynthetic process
0.40	GO:0042180	cellular ketone metabolic process
0.39	GO:0008584	male gonad development
0.37	GO:1901362	organic cyclic compound biosynthetic process

0.82	GO:0003865	3-oxo-5-alpha-steroid 4-dehydrogenase activity
0.40	GO:0009917	sterol 5-alpha reductase activity
0.40	GO:0030283	testosterone dehydrogenase [NAD(P)] activity

0.49	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

0.82

EC:1.3.99.5

GO:0003865

tr|T1G4L3|T1G4L3_HELRO
Uncharacterized protein
Search

PLOD3

0.79	Procollagen lysine 2-oxoglutarate 5-dioxygenase 3

0.54	GO:0046947	hydroxylysine biosynthetic process
0.53	GO:0017185	peptidyl-lysine hydroxylation
0.53	GO:0055114	oxidation-reduction process
0.52	GO:0001886	endothelial cell morphogenesis
0.52	GO:0070831	basement membrane assembly
0.51	GO:0042311	vasodilation
0.51	GO:0048730	epidermis morphogenesis
0.50	GO:0060425	lung morphogenesis
0.50	GO:0032963	collagen metabolic process
0.50	GO:0030199	collagen fibril organization

0.77	GO:0031418	L-ascorbic acid binding
0.73	GO:0008475	procollagen-lysine 5-dioxygenase activity
0.61	GO:0005506	iron ion binding
0.55	GO:0033823	procollagen glucosyltransferase activity
0.35	GO:0050211	procollagen galactosyltransferase activity
0.33	GO:0005515	protein binding

0.59	GO:0005783	endoplasmic reticulum
0.48	GO:0005802	trans-Golgi network
0.46	GO:0031012	extracellular matrix
0.37	GO:0005581	collagen trimer
0.37	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0098588	bounding membrane of organelle
0.36	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.34	GO:0048471	perinuclear region of cytoplasm
0.30	GO:0016021	integral component of membrane

0.73

EC:1.14.11.4

GO:0008475

tr|T1G4L4|T1G4L4_HELRO
Uncharacterized protein
Search

0.54	GO:0007094	mitotic spindle assembly checkpoint
0.53	GO:0007186	G-protein coupled receptor signaling pathway
0.45	GO:0090268	activation of mitotic cell cycle spindle assembly checkpoint
0.44	GO:1901925	negative regulation of protein import into nucleus during spindle assembly checkpoint
0.42	GO:0044774	mitotic DNA integrity checkpoint
0.41	GO:0006913	nucleocytoplasmic transport
0.40	GO:0016180	snRNA processing
0.39	GO:0031087	deadenylation-independent decapping of nuclear-transcribed mRNA
0.38	GO:0016567	protein ubiquitination
0.38	GO:0051315	attachment of mitotic spindle microtubules to kinetochore

0.57	GO:0008528	G-protein coupled peptide receptor activity
0.39	GO:0004087	carbamoyl-phosphate synthase (ammonia) activity
0.38	GO:0004842	ubiquitin-protein transferase activity
0.38	GO:0003723	RNA binding
0.37	GO:0005509	calcium ion binding
0.36	GO:0017048	Rho GTPase binding
0.36	GO:0005096	GTPase activator activity
0.36	GO:0009982	pseudouridine synthase activity
0.35	GO:0004222	metalloendopeptidase activity
0.35	GO:0004386	helicase activity

0.43	GO:0044428	nuclear part
0.42	GO:0070013	intracellular organelle lumen
0.41	GO:0000777	condensed chromosome kinetochore
0.39	GO:0020011	apicoplast
0.39	GO:0012505	endomembrane system
0.38	GO:0000428	DNA-directed RNA polymerase complex
0.38	GO:0000932	P-body
0.37	GO:0031967	organelle envelope
0.37	GO:0072686	mitotic spindle
0.36	GO:0000785	chromatin

0.39	EC:6.3.4.16	GO:0004087
0.39	KEGG:R00149	GO:0004087

tr|T1G4L5|T1G4L5_HELRO
Uncharacterized protein
Search

NGLY1

0.86	peptide-N(4)-(N-acetyl-beta- glucosaminyl)asparagine amidase

0.83	GO:0006516	glycoprotein catabolic process
0.47	GO:0006517	protein deglycosylation
0.43	GO:0006515	protein quality control for misfolded or incompletely synthesized proteins
0.43	GO:0045454	cell redox homeostasis
0.39	GO:0048671	negative regulation of collateral sprouting
0.39	GO:0030433	ubiquitin-dependent ERAD pathway
0.35	GO:1904587	response to glycoprotein
0.34	GO:0010188	response to microbial phytotoxin
0.34	GO:0006487	protein N-linked glycosylation
0.34	GO:0010193	response to ozone

0.48	GO:0000224	peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity
0.37	GO:0047134	protein-disulfide reductase activity
0.36	GO:0015035	protein disulfide oxidoreductase activity
0.34	GO:0030144	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity
0.34	GO:0030246	carbohydrate binding
0.33	GO:0046872	metal ion binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.48	GO:0005737	cytoplasm
0.38	GO:0005634	nucleus
0.33	GO:0005615	extracellular space
0.33	GO:0012505	endomembrane system
0.30	GO:0016020	membrane

0.48

EC:3.5.1.52

GO:0000224

tr|T1G4L6|T1G4L6_HELRO
Uncharacterized protein
Search

0.69	BTB/POZ domain-containing protein KCTD16

0.77	GO:0051260	protein homooligomerization
0.48	GO:0090327	negative regulation of locomotion involved in locomotory behavior
0.47	GO:0002121	inter-male aggressive behavior
0.47	GO:0008049	male courtship behavior
0.46	GO:0030431	sleep

0.35

GO:0004114

3',5'-cyclic-nucleotide phosphodiesterase activity

0.35

GO:0004114

tr|T1G4L7|T1G4L7_HELRO
Uncharacterized protein
Search

HGH1

0.87	Brain protein 16

tr|T1G4L8|T1G4L8_HELRO
Uncharacterized protein
Search

0.71	RNA-binding protein fusilli

0.48	GO:0043484	regulation of RNA splicing
0.41	GO:0007173	epidermal growth factor receptor signaling pathway
0.34	GO:0008380	RNA splicing
0.34	GO:0006397	mRNA processing
0.33	GO:0043547	positive regulation of GTPase activity

0.57	GO:0003723	RNA binding
0.33	GO:0005096	GTPase activator activity
0.33	GO:0008270	zinc ion binding

0.34	GO:0005634	nucleus
0.34	GO:0019013	viral nucleocapsid
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016020	membrane

tr|T1G4L9|T1G4L9_HELRO
Uncharacterized protein
Search

0.67	E3 ubiquitin-protein ligase DTX3L

0.56	GO:1901666	positive regulation of NAD+ ADP-ribosyltransferase activity
0.55	GO:2000646	positive regulation of receptor catabolic process
0.55	GO:1902965	regulation of protein localization to early endosome
0.55	GO:1905668	positive regulation of protein localization to endosome
0.55	GO:0035563	positive regulation of chromatin binding
0.55	GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining
0.54	GO:0051444	negative regulation of ubiquitin-protein transferase activity
0.54	GO:0033522	histone H2A ubiquitination
0.54	GO:0002230	positive regulation of defense response to virus by host
0.54	GO:0033523	histone H2B ubiquitination

0.56	GO:0097677	STAT family protein binding
0.51	GO:0004842	ubiquitin-protein transferase activity
0.50	GO:0042393	histone binding
0.50	GO:0044389	ubiquitin-like protein ligase binding
0.50	GO:0008270	zinc ion binding
0.49	GO:0016874	ligase activity
0.48	GO:0008047	enzyme activator activity
0.48	GO:0004857	enzyme inhibitor activity
0.44	GO:0005112	Notch binding
0.42	GO:0061659	ubiquitin-like protein ligase activity

0.51	GO:0005769	early endosome
0.50	GO:0005764	lysosome
0.46	GO:0005654	nucleoplasm
0.46	GO:0005829	cytosol
0.42	GO:0043234	protein complex
0.35	GO:0098852	lytic vacuole membrane
0.35	GO:0010008	endosome membrane
0.33	GO:0035861	site of double-strand break
0.30	GO:0016021	integral component of membrane

0.49	EC:6	GO:0016874
0.51	KEGG:R03876	GO:0004842

tr|T1G4M0|T1G4M0_HELRO
Uncharacterized protein
Search

0.81	GO:0007094	mitotic spindle assembly checkpoint
0.63	GO:0006468	protein phosphorylation
0.48	GO:0031134	sister chromatid biorientation
0.47	GO:0034501	protein localization to kinetochore
0.46	GO:0034508	centromere complex assembly
0.45	GO:0016236	macroautophagy
0.35	GO:0035556	intracellular signal transduction

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0042802	identical protein binding
0.35	GO:0004871	signal transducer activity

0.45	GO:0000778	condensed nuclear chromosome kinetochore
0.30	GO:0016020	membrane

tr|T1G4M1|T1G4M1_HELRO
Uncharacterized protein
Search

EHMT2

0.63	Euchromatic histone-lysine N-methyltransferase 2

0.79	GO:0034968	histone lysine methylation
0.50	GO:0071314	cellular response to cocaine
0.50	GO:0061647	histone H3-K9 modification
0.50	GO:0010424	DNA methylation on cytosine within a CG sequence
0.50	GO:0036166	phenotypic switching
0.49	GO:1902902	negative regulation of autophagosome assembly
0.49	GO:0048148	behavioral response to cocaine
0.48	GO:0048665	neuron fate specification
0.48	GO:0007130	synaptonemal complex assembly
0.47	GO:0035265	organ growth

0.85	GO:0002039	p53 binding
0.79	GO:0018024	histone-lysine N-methyltransferase activity
0.63	GO:0008270	zinc ion binding
0.51	GO:0070742	C2H2 zinc finger domain binding
0.48	GO:1990841	promoter-specific chromatin binding
0.45	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.34	GO:0102568	phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
0.34	GO:0102567	phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
0.34	GO:0004623	phospholipase A2 activity

0.67	GO:0005694	chromosome
0.61	GO:0005634	nucleus
0.44	GO:0031974	membrane-enclosed lumen
0.40	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.79

GO:0018024

tr|T1G4M2|T1G4M2_HELRO
Uncharacterized protein
Search

0.64	Cyclic nucleotide-gated cation channel

0.53	GO:0034220	ion transmembrane transport
0.48	GO:0071804	cellular potassium ion transport
0.45	GO:0034765	regulation of ion transmembrane transport
0.40	GO:0042391	regulation of membrane potential
0.40	GO:0007601	visual perception
0.39	GO:0035845	photoreceptor cell outer segment organization
0.39	GO:0050962	detection of light stimulus involved in sensory perception
0.39	GO:0019935	cyclic-nucleotide-mediated signaling
0.39	GO:0045494	photoreceptor cell maintenance
0.38	GO:0007608	sensory perception of smell

0.60	GO:0005216	ion channel activity
0.50	GO:0022836	gated channel activity
0.48	GO:0015079	potassium ion transmembrane transporter activity
0.39	GO:0030553	cGMP binding
0.34	GO:0030552	cAMP binding
0.32	GO:0005515	protein binding

0.41	GO:0017071	intracellular cyclic nucleotide activated cation channel complex
0.38	GO:0001750	photoreceptor outer segment
0.38	GO:0005887	integral component of plasma membrane
0.34	GO:0060170	ciliary membrane
0.34	GO:0043195	terminal bouton
0.33	GO:0030660	Golgi-associated vesicle membrane
0.33	GO:0000139	Golgi membrane

tr|T1G4M3|T1G4M3_HELRO
Uncharacterized protein
Search

0.77	Putative heteroproteinous nuclear ribonucleoprotein r rrm superfamily (Fragment)

0.45	GO:0046011	regulation of oskar mRNA translation
0.44	GO:1900073	regulation of neuromuscular synaptic transmission
0.44	GO:0007310	oocyte dorsal/ventral axis specification
0.44	GO:0045886	negative regulation of synaptic growth at neuromuscular junction
0.44	GO:0046843	dorsal appendage formation
0.40	GO:0000398	mRNA splicing, via spliceosome
0.37	GO:0030010	establishment of cell polarity
0.36	GO:0000226	microtubule cytoskeleton organization
0.35	GO:0006468	protein phosphorylation
0.32	GO:0055114	oxidation-reduction process

0.59	GO:0003723	RNA binding
0.35	GO:0004674	protein serine/threonine kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0016491	oxidoreductase activity

0.55	GO:0019013	viral nucleocapsid
0.50	GO:0030529	intracellular ribonucleoprotein complex
0.44	GO:0098975	postsynapse of neuromuscular junction
0.38	GO:0044428	nuclear part
0.37	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

0.35

GO:0004674

tr|T1G4M4|T1G4M4_HELRO
Uncharacterized protein
Search

0.80	Putative syntaxin-binding protein 2 (Fragment)

0.35	GO:0006904	vesicle docking involved in exocytosis
0.35	GO:0065007	biological regulation
0.35	GO:0023052	signaling
0.34	GO:0007154	cell communication
0.34	GO:0051716	cellular response to stimulus
0.34	GO:0008345	larval locomotory behavior
0.34	GO:0071599	otic vesicle development
0.34	GO:0016043	cellular component organization
0.34	GO:0044265	cellular macromolecule catabolic process
0.33	GO:0043412	macromolecule modification

0.35	GO:0005509	calcium ion binding
0.35	GO:0044877	macromolecular complex binding
0.35	GO:0005515	protein binding
0.34	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.34	GO:0017076	purine nucleotide binding
0.34	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.34	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.33	GO:0003682	chromatin binding
0.33	GO:0016301	kinase activity
0.33	GO:0017111	nucleoside-triphosphatase activity

0.34	GO:0005634	nucleus
0.34	GO:0043234	protein complex
0.34	GO:0005844	polysome
0.33	GO:0031514	motile cilium
0.33	GO:1902494	catalytic complex
0.33	GO:0000785	chromatin
0.33	GO:0070013	intracellular organelle lumen
0.33	GO:0099023	tethering complex
0.32	GO:0005886	plasma membrane
0.32	GO:0044444	cytoplasmic part

0.34	EC:2.4.2.30	GO:0003950
0.33	KEGG:R01082	GO:0004333

tr|T1G4M5|T1G4M5_HELRO
Uncharacterized protein
Search

SPATA13

0.95	Spermatogenesis-associated protein 13

0.78	GO:0035023	regulation of Rho protein signal transduction
0.66	GO:0065009	regulation of molecular function
0.41	GO:0035556	intracellular signal transduction
0.41	GO:0046847	filopodium assembly
0.41	GO:0030032	lamellipodium assembly
0.39	GO:0030334	regulation of cell migration
0.39	GO:0016477	cell migration

0.78	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.41	GO:0048365	Rac GTPase binding
0.38	GO:0042802	identical protein binding

0.41	GO:0032587	ruffle membrane
0.40	GO:0030175	filopodium
0.40	GO:0030027	lamellipodium
0.40	GO:0005654	nucleoplasm
0.39	GO:0005829	cytosol
0.35	GO:0005581	collagen trimer
0.34	GO:0005576	extracellular region

tr|T1G4M6|T1G4M6_HELRO
Synaptotagmin 1a
Search

0.77	Synaptotagmin-1 (inferred by orthology to a C. elegans protein)

0.82	GO:0099643	signal release from synapse
0.82	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.75	GO:0006836	neurotransmitter transport
0.72	GO:0001505	regulation of neurotransmitter levels
0.68	GO:0051649	establishment of localization in cell
0.44	GO:0060627	regulation of vesicle-mediated transport
0.44	GO:0017156	calcium ion regulated exocytosis
0.44	GO:0097479	synaptic vesicle localization
0.44	GO:0099003	vesicle-mediated transport in synapse
0.43	GO:1903530	regulation of secretion by cell

0.81	GO:0005544	calcium-dependent phospholipid binding
0.44	GO:0000149	SNARE binding
0.41	GO:0001786	phosphatidylserine binding
0.41	GO:0005509	calcium ion binding
0.39	GO:0030276	clathrin binding
0.39	GO:0042803	protein homodimerization activity
0.35	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity

0.81	GO:0008021	synaptic vesicle
0.41	GO:0099501	exocytic vesicle membrane
0.41	GO:0043195	terminal bouton
0.40	GO:0031594	neuromuscular junction
0.35	GO:0031301	integral component of organelle membrane
0.35	GO:0030054	cell junction
0.35	GO:0005886	plasma membrane

0.35	EC:2.7.1.154	GO:0035005
0.35	KEGG:R05795	GO:0035005

tr|T1G4M7|T1G4M7_HELRO
Uncharacterized protein
Search

tr|T1G4M8|T1G4M8_HELRO
Uncharacterized protein
Search

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.42	GO:0060536	cartilage morphogenesis
0.38	GO:0048793	pronephros development
0.36	GO:0007267	cell-cell signaling
0.36	GO:0007399	nervous system development
0.36	GO:0033626	positive regulation of integrin activation by cell surface receptor linked signal transduction
0.36	GO:0002314	germinal center B cell differentiation
0.36	GO:0002315	marginal zone B cell differentiation
0.35	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.35	GO:0048536	spleen development

0.70	GO:0005509	calcium ion binding
0.36	GO:0005427	proton-dependent oligopeptide secondary active transmembrane transporter activity
0.35	GO:0005178	integrin binding

0.56	GO:0005886	plasma membrane
0.34	GO:0009986	cell surface
0.34	GO:0030054	cell junction
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

tr|T1G4M9|T1G4M9_HELRO
Uncharacterized protein
Search

INPP5E

0.82	Inositol polyphosphate-5-phosphatase E

0.81	GO:0046856	phosphatidylinositol dephosphorylation
0.47	GO:0046855	inositol phosphate dephosphorylation
0.47	GO:0032402	melanosome transport
0.47	GO:0035850	epithelial cell differentiation involved in kidney development
0.47	GO:1902017	regulation of cilium assembly
0.46	GO:0060041	retina development in camera-type eye
0.45	GO:0060271	cilium assembly
0.37	GO:0006661	phosphatidylinositol biosynthetic process
0.36	GO:0048208	COPII vesicle coating
0.35	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling

0.52	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
0.40	GO:0046030	inositol trisphosphate phosphatase activity
0.39	GO:0034594	phosphatidylinositol trisphosphate phosphatase activity
0.37	GO:1990651	inositol-1,2,4,5,6-pentakisphosphate 5-phosphatase activity
0.37	GO:1990650	inositol-2,4,5,6-tetrakisphosphate 5-phosphatase activity
0.37	GO:1990649	inositol-1,2,4,5-tetrakisphosphate 5-phosphatase activity
0.37	GO:0030487	inositol-4,5-bisphosphate 5-phosphatase activity
0.37	GO:0052659	inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity
0.37	GO:0043813	phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity
0.36	GO:0005509	calcium ion binding

0.49	GO:0005930	axoneme
0.47	GO:0000139	Golgi membrane
0.39	GO:0001726	ruffle
0.38	GO:0031985	Golgi cisterna
0.34	GO:0005886	plasma membrane
0.34	GO:0005783	endoplasmic reticulum
0.33	GO:0005829	cytosol
0.32	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.52	EC:3.1.3.36	GO:0004439
0.52	KEGG:R04404	GO:0004439

tr|T1G4N0|T1G4N0_HELRO
Kinesin-like protein
Search

0.74	GO:0007018	microtubule-based movement
0.55	GO:0007019	microtubule depolymerization
0.50	GO:0044782	cilium organization
0.50	GO:0120031	plasma membrane bounded cell projection assembly
0.47	GO:0070925	organelle assembly
0.37	GO:1905833	negative regulation of microtubule nucleation
0.36	GO:0007051	spindle organization
0.36	GO:0031122	cytoplasmic microtubule organization
0.36	GO:0051661	maintenance of centrosome location
0.36	GO:0009794	regulation of mitotic cell cycle, embryonic

0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0042802	identical protein binding
0.40	GO:0016887	ATPase activity
0.37	GO:0008270	zinc ion binding
0.34	GO:0042302	structural constituent of cuticle

0.61	GO:0015630	microtubule cytoskeleton
0.60	GO:0044430	cytoskeletal part
0.57	GO:0099512	supramolecular fiber
0.44	GO:0043234	protein complex
0.40	GO:0044444	cytoplasmic part
0.35	GO:0000779	condensed chromosome, centromeric region
0.33	GO:0044441	ciliary part
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.40

GO:0016887

tr|T1G4N1|T1G4N1_HELRO
Uncharacterized protein
Search

0.39	Histone-lysine N-methyltransferase

0.78	GO:0034968	histone lysine methylation
0.49	GO:0018026	peptidyl-lysine monomethylation
0.46	GO:0043516	regulation of DNA damage response, signal transduction by p53 class mediator
0.43	GO:0000122	negative regulation of transcription by RNA polymerase II
0.41	GO:0000077	DNA damage checkpoint
0.40	GO:0030261	chromosome condensation
0.36	GO:0051301	cell division
0.36	GO:0007049	cell cycle
0.35	GO:0006351	transcription, DNA-templated
0.34	GO:0035067	negative regulation of histone acetylation

0.79	GO:0018024	histone-lysine N-methyltransferase activity
0.45	GO:0002039	p53 binding
0.44	GO:0003714	transcription corepressor activity
0.32	GO:0016853	isomerase activity

0.42	GO:0005700	polytene chromosome
0.41	GO:0005829	cytosol
0.40	GO:0005634	nucleus
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.79

GO:0018024

tr|T1G4N2|T1G4N2_HELRO
Uncharacterized protein
Search

0.33	Tyrosine-protein phosphatase

0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.52	GO:0098507	polynucleotide 5' dephosphorylation
0.40	GO:0016070	RNA metabolic process
0.34	GO:0010467	gene expression

0.79	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.75	GO:0004725	protein tyrosine phosphatase activity
0.52	GO:0004651	polynucleotide 5'-phosphatase activity
0.51	GO:0098519	nucleotide phosphatase activity, acting on free nucleotides
0.41	GO:0003723	RNA binding
0.39	GO:0004484	mRNA guanylyltransferase activity
0.35	GO:0032550	purine ribonucleoside binding
0.35	GO:0019001	guanyl nucleotide binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.50	GO:0045171	intercellular bridge
0.49	GO:0001650	fibrillar center
0.49	GO:0016607	nuclear speck

0.79

GO:0008138

tr|T1G4N3|T1G4N3_HELRO
Uncharacterized protein
Search

tr|T1G4N4|T1G4N4_HELRO
Uncharacterized protein
Search

BZW2

0.82	Basic leucine zipper and W2 domain-containing protein 1-A

0.46	GO:0007399	nervous system development
0.45	GO:0030154	cell differentiation
0.39	GO:0097659	nucleic acid-templated transcription
0.39	GO:2001141	regulation of RNA biosynthetic process
0.39	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.39	GO:0010468	regulation of gene expression
0.38	GO:0010467	gene expression
0.38	GO:0034645	cellular macromolecule biosynthetic process

0.78	GO:0045296	cadherin binding
0.36	GO:0003723	RNA binding

0.47	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

tr|T1G4N5|T1G4N5_HELRO
Uncharacterized protein
Search

HTRA2

0.64	HtrA serine peptidase 2

0.61	GO:0006508	proteolysis
0.55	GO:1904924	negative regulation of mitophagy in response to mitochondrial depolarization
0.53	GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
0.53	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
0.53	GO:0035458	cellular response to interferon-beta
0.52	GO:0070207	protein homotrimerization
0.52	GO:0071300	cellular response to retinoic acid
0.52	GO:0007628	adult walking behavior
0.51	GO:1903955	positive regulation of protein targeting to mitochondrion
0.51	GO:0040008	regulation of growth

0.69	GO:0004252	serine-type endopeptidase activity
0.47	GO:0042802	identical protein binding
0.43	GO:0005520	insulin-like growth factor binding
0.34	GO:0005044	scavenger receptor activity
0.34	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor
0.33	GO:0051082	unfolded protein binding
0.33	GO:0005507	copper ion binding

0.55	GO:1905370	serine-type endopeptidase complex
0.53	GO:0035631	CD40 receptor complex
0.50	GO:0005758	mitochondrial intermembrane space
0.47	GO:0009898	cytoplasmic side of plasma membrane
0.46	GO:0000785	chromatin
0.46	GO:0005829	cytosol
0.45	GO:0005856	cytoskeleton
0.42	GO:0005634	nucleus
0.39	GO:0016006	Nebenkern
0.39	GO:0005576	extracellular region

0.69

GO:0004252

tr|T1G4N6|T1G4N6_HELRO
Uncharacterized protein
Search

0.76	Transcription elongation factor S-II

0.60	GO:0006414	translational elongation
0.58	GO:0006351	transcription, DNA-templated
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.33	GO:0016477	cell migration
0.33	GO:0043547	positive regulation of GTPase activity

0.63	GO:0008270	zinc ion binding
0.61	GO:0003746	translation elongation factor activity
0.33	GO:0003677	DNA binding
0.33	GO:0005096	GTPase activator activity

0.60	GO:0005634	nucleus
0.34	GO:0005925	focal adhesion
0.30	GO:0016020	membrane

tr|T1G4N7|T1G4N7_HELRO
Uncharacterized protein
Search

OPA1

0.94	Optic atrophy protein 1

0.78	GO:0006915	apoptotic process
0.75	GO:0007005	mitochondrion organization
0.53	GO:0097749	membrane tubulation
0.50	GO:0090201	negative regulation of release of cytochrome c from mitochondria
0.49	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
0.49	GO:0090398	cellular senescence
0.48	GO:0048284	organelle fusion
0.47	GO:0003374	dynamin family protein polymerization involved in mitochondrial fission
0.46	GO:0046039	GTP metabolic process
0.46	GO:0007601	visual perception

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.51	GO:1901612	cardiolipin binding
0.50	GO:0070300	phosphatidic acid binding
0.42	GO:0008017	microtubule binding
0.36	GO:0019900	kinase binding
0.33	GO:0003743	translation initiation factor activity
0.33	GO:0000287	magnesium ion binding

0.61	GO:0005739	mitochondrion
0.47	GO:0031970	organelle envelope lumen
0.46	GO:0031968	organelle outer membrane
0.43	GO:0005654	nucleoplasm
0.43	GO:0005829	cytosol
0.41	GO:0019866	organelle inner membrane
0.38	GO:0030425	dendrite
0.37	GO:0031312	extrinsic component of organelle membrane
0.34	GO:1904115	axon cytoplasm
0.33	GO:0005852	eukaryotic translation initiation factor 3 complex

tr|T1G4N8|T1G4N8_HELRO
Uncharacterized protein
Search

DPY19L1

0.57	Dpy-19-like C-mannosyltransferase 1

0.61	GO:0097502	mannosylation
0.53	GO:0018317	protein C-linked glycosylation via tryptophan
0.35	GO:0007399	nervous system development
0.35	GO:0030154	cell differentiation
0.34	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
0.34	GO:0006468	protein phosphorylation
0.34	GO:0005975	carbohydrate metabolic process

0.61	GO:0000030	mannosyltransferase activity
0.34	GO:0004702	signal transducer, downstream of receptor, with serine/threonine kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003676	nucleic acid binding

0.48	GO:0005637	nuclear inner membrane
0.38	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.61

GO:0000030

tr|T1G4N9|T1G4N9_HELRO
Uncharacterized protein
Search

0.74	Putative syntaxin-binding protein 2 (Fragment)

0.51	GO:0006904	vesicle docking involved in exocytosis
0.42	GO:0006468	protein phosphorylation

0.44	GO:0004674	protein serine/threonine kinase activity
0.39	GO:0030554	adenyl nucleotide binding
0.39	GO:0032555	purine ribonucleotide binding
0.39	GO:0008144	drug binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0044425

membrane part

0.44

GO:0004674

tr|T1G4P0|T1G4P0_HELRO
Uncharacterized protein
Search

0.77	RFX-like transcription factor daf-19 (inferred by orthology to a C. elegans protein)

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.43	GO:0007605	sensory perception of sound
0.41	GO:0007399	nervous system development
0.39	GO:0016358	dendrite development
0.39	GO:0120036	plasma membrane bounded cell projection organization
0.38	GO:0048468	cell development
0.38	GO:0032989	cellular component morphogenesis
0.35	GO:0033363	secretory granule organization

0.54	GO:0003677	DNA binding
0.37	GO:0001067	regulatory region nucleic acid binding
0.35	GO:0003700	DNA binding transcription factor activity

0.40	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|T1G4P1|T1G4P1_HELRO
Uncharacterized protein
Search

0.86	Serine protease inhibitor dipetalogastin (Fragment)

0.63	GO:0043113	receptor clustering
0.62	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway
0.42	GO:0006508	proteolysis
0.37	GO:0010951	negative regulation of endopeptidase activity
0.35	GO:0051260	protein homooligomerization
0.33	GO:0016310	phosphorylation

0.64	GO:0005509	calcium ion binding
0.64	GO:0043236	laminin binding
0.42	GO:0008233	peptidase activity
0.38	GO:0004867	serine-type endopeptidase inhibitor activity
0.33	GO:0016301	kinase activity

0.45	GO:0005886	plasma membrane
0.35	GO:0005605	basal lamina
0.33	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.42

GO:0008233

tr|T1G4P2|T1G4P2_HELRO
Uncharacterized protein
Search

ABCG2

0.91	Placenta-specific ATP-binding cassette transporter

0.50	GO:0046415	urate metabolic process
0.49	GO:0055085	transmembrane transport
0.48	GO:0033344	cholesterol efflux
0.42	GO:0015893	drug transport
0.38	GO:0097744	urate salt excretion
0.37	GO:1904612	response to 2,3,7,8-tetrachlorodibenzodioxine
0.37	GO:0019389	glucuronoside metabolic process
0.37	GO:1904479	negative regulation of intestinal absorption
0.37	GO:0060136	embryonic process involved in female pregnancy
0.37	GO:0051593	response to folic acid

0.61	GO:0016887	ATPase activity
0.57	GO:0015399	primary active transmembrane transporter activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0017127	cholesterol transporter activity
0.46	GO:0042803	protein homodimerization activity
0.37	GO:0042910	xenobiotic transmembrane transporter activity
0.37	GO:0015238	drug transmembrane transporter activity
0.35	GO:0008092	cytoskeletal protein binding

0.46	GO:0016324	apical plasma membrane
0.45	GO:0043235	receptor complex
0.42	GO:0005634	nucleus
0.36	GO:0031966	mitochondrial membrane
0.33	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

0.61

GO:0016887

tr|T1G4P3|T1G4P3_HELRO
Uncharacterized protein
Search

0.47	GO:0035023	regulation of Rho protein signal transduction
0.45	GO:0048496	maintenance of animal organ identity
0.44	GO:0036211	protein modification process
0.44	GO:0045494	photoreceptor cell maintenance
0.44	GO:0035315	hair cell differentiation
0.44	GO:0060113	inner ear receptor cell differentiation
0.43	GO:0065009	regulation of molecular function
0.43	GO:0007605	sensory perception of sound
0.42	GO:0016311	dephosphorylation
0.42	GO:0044267	cellular protein metabolic process

0.47	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.44	GO:0004725	protein tyrosine phosphatase activity
0.43	GO:0017022	myosin binding
0.43	GO:0005518	collagen binding
0.42	GO:0004672	protein kinase activity
0.41	GO:0042803	protein homodimerization activity
0.40	GO:0005509	calcium ion binding
0.39	GO:0032559	adenyl ribonucleotide binding
0.39	GO:0008144	drug binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding

0.48	GO:0005604	basement membrane
0.46	GO:0060171	stereocilium membrane
0.46	GO:0002142	stereocilia ankle link complex
0.45	GO:1990696	USH2 complex
0.45	GO:1990075	periciliary membrane compartment
0.44	GO:0001917	photoreceptor inner segment
0.44	GO:0032391	photoreceptor connecting cilium
0.43	GO:0036064	ciliary basal body
0.43	GO:0016324	apical plasma membrane
0.42	GO:0005938	cell cortex

0.44

GO:0004725

tr|T1G4P4|T1G4P4_HELRO
Uncharacterized protein
Search

0.56	ER membrane protein complex subunit

0.44	GO:0034975	protein folding in endoplasmic reticulum
0.35	GO:0035335	peptidyl-tyrosine dephosphorylation
0.32	GO:0006508	proteolysis

0.35	GO:0004725	protein tyrosine phosphatase activity
0.33	GO:0008234	cysteine-type peptidase activity

0.84

GO:0072546

ER membrane protein complex

0.35

GO:0004725

tr|T1G4P5|T1G4P5_HELRO
Uncharacterized protein
Search

SVOP

0.89	Transporter SVOPL

0.55	GO:0055085	transmembrane transport
0.35	GO:0010735	positive regulation of transcription via serum response element binding
0.34	GO:0030042	actin filament depolymerization
0.33	GO:0006546	glycine catabolic process
0.33	GO:0008643	carbohydrate transport
0.33	GO:0055114	oxidation-reduction process

0.55	GO:0022857	transmembrane transporter activity
0.35	GO:0043914	NADPH:sulfur oxidoreductase activity
0.34	GO:0016642	oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor
0.34	GO:0003779	actin binding
0.34	GO:0071949	FAD binding
0.32	GO:0046872	metal ion binding

0.41	GO:0030672	synaptic vesicle membrane
0.39	GO:0030054	cell junction
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.35

GO:0043914

tr|T1G4P6|T1G4P6_HELRO
Uncharacterized protein
Search

0.91	Angiopoietin-related protein 4 (Fragment)

0.72	GO:0001525	angiogenesis
0.69	GO:0043066	negative regulation of apoptotic process
0.47	GO:0030199	collagen fibril organization
0.47	GO:0051005	negative regulation of lipoprotein lipase activity
0.44	GO:2000351	regulation of endothelial cell apoptotic process
0.44	GO:0070328	triglyceride homeostasis
0.40	GO:0007596	blood coagulation
0.38	GO:0035634	response to stilbenoid
0.38	GO:0048513	animal organ development
0.38	GO:0055085	transmembrane transport

0.42	GO:0042802	identical protein binding
0.41	GO:0004857	enzyme inhibitor activity
0.39	GO:0022857	transmembrane transporter activity
0.38	GO:0030674	protein binding, bridging
0.37	GO:0005509	calcium ion binding
0.37	GO:0005102	receptor binding
0.34	GO:0003735	structural constituent of ribosome

0.67	GO:0044421	extracellular region part
0.36	GO:0031982	vesicle
0.35	GO:0032991	macromolecular complex
0.34	GO:0043232	intracellular non-membrane-bounded organelle
0.33	GO:0044444	cytoplasmic part
0.30	GO:0016020	membrane

tr|T1G4P7|T1G4P7_HELRO
Uncharacterized protein
Search

0.12	Putative syntaxin-binding protein 2 (Fragment)

0.37	GO:0033198	response to ATP
0.37	GO:0035590	purinergic nucleotide receptor signaling pathway
0.37	GO:0007605	sensory perception of sound
0.36	GO:0060079	excitatory postsynaptic potential
0.36	GO:0035335	peptidyl-tyrosine dephosphorylation
0.36	GO:0016575	histone deacetylation
0.34	GO:0098655	cation transmembrane transport
0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression

0.37	GO:0004931	extracellularly ATP-gated cation channel activity
0.37	GO:0016502	nucleotide receptor activity
0.37	GO:0035586	purinergic receptor activity
0.36	GO:0004725	protein tyrosine phosphatase activity
0.36	GO:0004407	histone deacetylase activity
0.34	GO:0046872	metal ion binding
0.33	GO:0016740	transferase activity

0.36	GO:0098794	postsynapse
0.35	GO:0005887	integral component of plasma membrane

0.36

GO:0004725

tr|T1G4P8|T1G4P8_HELRO
Uncharacterized protein
Search

VAMP3

0.78	Vesicle-associated membrane protein 1

0.69	GO:0016192	vesicle-mediated transport
0.51	GO:0090174	organelle membrane fusion
0.50	GO:0016050	vesicle organization
0.48	GO:0061951	establishment of protein localization to plasma membrane
0.48	GO:1903540	establishment of protein localization to postsynaptic membrane
0.48	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels
0.47	GO:0099637	neurotransmitter receptor transport
0.47	GO:0032940	secretion by cell
0.47	GO:0097120	receptor localization to synapse
0.46	GO:0060291	long-term synaptic potentiation

0.51	GO:0000149	SNARE binding
0.47	GO:0005484	SNAP receptor activity
0.44	GO:0005516	calmodulin binding
0.43	GO:0005543	phospholipid binding
0.38	GO:0008022	protein C-terminus binding
0.38	GO:0048306	calcium-dependent protein binding
0.37	GO:0044325	ion channel binding
0.37	GO:0017022	myosin binding
0.36	GO:0032403	protein complex binding
0.36	GO:0042802	identical protein binding

0.53	GO:0031201	SNARE complex
0.50	GO:0099503	secretory vesicle
0.47	GO:0030659	cytoplasmic vesicle membrane
0.46	GO:0048471	perinuclear region of cytoplasm
0.46	GO:0098793	presynapse
0.46	GO:0030133	transport vesicle
0.46	GO:0098805	whole membrane
0.45	GO:0098588	bounding membrane of organelle
0.44	GO:0005802	trans-Golgi network
0.44	GO:0000322	storage vacuole

0.33

EC:1.13.11

GO:0016702

tr|T1G4P9|T1G4P9_HELRO
Innexin
Search

INX

0.65	Innexin unc-9

0.58	GO:0006811	ion transport
0.35	GO:0010644	cell communication by electrical coupling
0.35	GO:0048598	embryonic morphogenesis
0.34	GO:0007186	G-protein coupled receptor signaling pathway
0.32	GO:0055085	transmembrane transport

0.35	GO:0005243	gap junction channel activity
0.34	GO:0004930	G-protein coupled receptor activity

0.81	GO:0005921	gap junction
0.55	GO:0005886	plasma membrane
0.34	GO:0045202	synapse
0.32	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

tr|T1G4Q0|T1G4Q0_HELRO
Uncharacterized protein
Search

0.53	Histone demethylase

0.85	GO:0071557	histone H3-K27 demethylation
0.53	GO:0032259	methylation
0.53	GO:0060255	regulation of macromolecule metabolic process
0.48	GO:0045498	sex comb development
0.46	GO:0045746	negative regulation of Notch signaling pathway
0.45	GO:0035072	ecdysone-mediated induction of salivary gland cell autophagic cell death
0.45	GO:1905268	negative regulation of chromatin organization
0.44	GO:0071390	cellular response to ecdysone
0.44	GO:0071480	cellular response to gamma radiation
0.44	GO:0042060	wound healing

0.85	GO:0071558	histone demethylase activity (H3-K27 specific)
0.54	GO:0046872	metal ion binding
0.52	GO:0008168	methyltransferase activity
0.44	GO:1990841	promoter-specific chromatin binding
0.43	GO:0035257	nuclear hormone receptor binding

0.49	GO:0005634	nucleus
0.46	GO:0005705	polytene chromosome interband
0.45	GO:0035327	transcriptionally active chromatin
0.43	GO:0034708	methyltransferase complex
0.40	GO:0031974	membrane-enclosed lumen

0.52

GO:0008168

tr|T1G4Q1|T1G4Q1_HELRO
POU domain protein
Search

0.10	POU class 6 homeobox 2

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.48	GO:0007275	multicellular organism development
0.38	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.38	GO:0000904	cell morphogenesis involved in differentiation
0.38	GO:0120036	plasma membrane bounded cell projection organization
0.38	GO:0007608	sensory perception of smell
0.37	GO:0006935	chemotaxis

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.46	GO:0001067	regulatory region nucleic acid binding

0.61	GO:0005634	nucleus
0.46	GO:0015629	actin cytoskeleton
0.43	GO:0031974	membrane-enclosed lumen
0.40	GO:0044446	intracellular organelle part

tr|T1G4Q2|T1G4Q2_HELRO
Uncharacterized protein
Search

0.67	26S protease regulatory subunit

0.81	GO:1901800	positive regulation of proteasomal protein catabolic process
0.70	GO:0030163	protein catabolic process
0.53	GO:0006508	proteolysis
0.46	GO:0001824	blastocyst development
0.44	GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly
0.43	GO:0034976	response to endoplasmic reticulum stress
0.42	GO:0010243	response to organonitrogen compound
0.41	GO:0043632	modification-dependent macromolecule catabolic process
0.37	GO:0044267	cellular protein metabolic process
0.34	GO:0008063	Toll signaling pathway

0.82	GO:0036402	proteasome-activating ATPase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0008233	peptidase activity
0.43	GO:0017025	TBP-class protein binding

0.50	GO:1905369	endopeptidase complex
0.48	GO:0005737	cytoplasm
0.44	GO:0043234	protein complex
0.42	GO:0005634	nucleus
0.40	GO:0043233	organelle lumen
0.37	GO:0044446	intracellular organelle part
0.34	GO:0016234	inclusion body
0.34	GO:0045202	synapse
0.30	GO:0016020	membrane

0.52

GO:0008233

tr|T1G4Q3|T1G4Q3_HELRO
Uncharacterized protein
Search

0.82	GO:0017157	regulation of exocytosis
0.69	GO:0016192	vesicle-mediated transport
0.62	GO:0006886	intracellular protein transport
0.62	GO:0061025	membrane fusion
0.36	GO:0006413	translational initiation
0.36	GO:0006836	neurotransmitter transport
0.35	GO:0097480	establishment of synaptic vesicle localization
0.35	GO:0099504	synaptic vesicle cycle
0.35	GO:0099643	signal release from synapse
0.35	GO:0099531	presynaptic process involved in chemical synaptic transmission

0.81	GO:0000149	SNARE binding
0.72	GO:0005484	SNAP receptor activity
0.36	GO:0003743	translation initiation factor activity
0.33	GO:0003746	translation elongation factor activity
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.42	GO:0005622	intracellular
0.35	GO:0098793	presynapse
0.34	GO:0031982	vesicle
0.34	GO:0044306	neuron projection terminus
0.34	GO:0033267	axon part
0.34	GO:0012505	endomembrane system
0.33	GO:0098796	membrane protein complex
0.33	GO:0030054	cell junction
0.33	GO:0098805	whole membrane
0.33	GO:0098588	bounding membrane of organelle

tr|T1G4Q4|T1G4Q4_HELRO
Uncharacterized protein
Search

0.72	Snare protein syntaxin 1

0.82	GO:0017157	regulation of exocytosis
0.69	GO:0016192	vesicle-mediated transport
0.69	GO:0006886	intracellular protein transport
0.68	GO:0061025	membrane fusion
0.44	GO:0001956	positive regulation of neurotransmitter secretion
0.44	GO:2000463	positive regulation of excitatory postsynaptic potential
0.44	GO:1902803	regulation of synaptic vesicle transport
0.44	GO:0098693	regulation of synaptic vesicle cycle
0.42	GO:0010701	positive regulation of norepinephrine secretion
0.42	GO:0097480	establishment of synaptic vesicle localization

0.82	GO:0000149	SNARE binding
0.80	GO:0005484	SNAP receptor activity
0.44	GO:0019855	calcium channel inhibitor activity
0.44	GO:0019869	chloride channel inhibitor activity
0.41	GO:0019900	kinase binding
0.41	GO:0032028	myosin head/neck binding
0.40	GO:0043008	ATP-dependent protein binding
0.39	GO:0048306	calcium-dependent protein binding
0.39	GO:0047485	protein N-terminus binding
0.39	GO:0044325	ion channel binding

0.45	GO:0031201	SNARE complex
0.45	GO:0008021	synaptic vesicle
0.45	GO:0099501	exocytic vesicle membrane
0.43	GO:0030424	axon
0.42	GO:0031965	nuclear membrane
0.41	GO:0048787	presynaptic active zone membrane
0.39	GO:0005887	integral component of plasma membrane
0.39	GO:0042641	actomyosin
0.39	GO:0014069	postsynaptic density
0.39	GO:0034705	potassium channel complex

tr|T1G4Q5|T1G4Q5_HELRO
Uncharacterized protein
Search

0.42	GO:0048009	insulin-like growth factor receptor signaling pathway
0.42	GO:0040024	dauer larval development
0.41	GO:0008340	determination of adult lifespan
0.39	GO:0008104	protein localization
0.38	GO:0017157	regulation of exocytosis
0.38	GO:0006904	vesicle docking involved in exocytosis
0.37	GO:0006836	neurotransmitter transport
0.36	GO:0002790	peptide secretion
0.36	GO:0032509	endosome transport via multivesicular body sorting pathway
0.34	GO:0006468	protein phosphorylation

0.60	GO:0003924	GTPase activity
0.60	GO:0032550	purine ribonucleoside binding
0.60	GO:0019001	guanyl nucleotide binding
0.50	GO:0032555	purine ribonucleotide binding
0.50	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0005328	neurotransmitter:sodium symporter activity
0.36	GO:0032266	phosphatidylinositol-3-phosphate binding
0.36	GO:0043130	ubiquitin binding
0.35	GO:0003723	RNA binding
0.34	GO:0004672	protein kinase activity

0.56	GO:0005929	cilium
0.47	GO:0030992	intraciliary transport particle B
0.44	GO:0044430	cytoskeletal part
0.42	GO:0015630	microtubule cytoskeleton
0.41	GO:0032838	plasma membrane bounded cell projection cytoplasm
0.36	GO:0000814	ESCRT II complex
0.30	GO:0031224	intrinsic component of membrane

tr|T1G4Q6|T1G4Q6_HELRO
Uncharacterized protein
Search

0.42	Calmodulin

0.39	GO:1990954	establishment of protein localization to meiotic spindle pole body
0.39	GO:0044837	actomyosin contractile ring organization
0.39	GO:0000912	assembly of actomyosin apparatus involved in cytokinesis
0.38	GO:0006903	vesicle targeting
0.38	GO:0090307	mitotic spindle assembly
0.34	GO:0006468	protein phosphorylation

0.70	GO:0005509	calcium ion binding
0.40	GO:0032038	myosin II heavy chain binding
0.39	GO:0031489	myosin V binding
0.37	GO:0003676	nucleic acid binding
0.37	GO:0042802	identical protein binding
0.34	GO:0004672	protein kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.40	GO:0030427	site of polarized growth
0.39	GO:0044430	cytoskeletal part
0.39	GO:0015629	actin cytoskeleton
0.38	GO:0000935	division septum
0.38	GO:0005933	cellular bud
0.38	GO:0051286	cell tip
0.37	GO:0005937	mating projection
0.37	GO:0120038	plasma membrane bounded cell projection part
0.37	GO:0031982	vesicle
0.36	GO:0015630	microtubule cytoskeleton

tr|T1G4Q7|T1G4Q7_HELRO
Uncharacterized protein
Search

0.63	GO:0006468	protein phosphorylation
0.52	GO:0007147	female meiosis II
0.52	GO:0032515	negative regulation of phosphoprotein phosphatase activity
0.52	GO:0051441	positive regulation of ubiquitin-protein ligase activity involved in meiotic cell cycle
0.51	GO:0000086	G2/M transition of mitotic cell cycle
0.49	GO:0018209	peptidyl-serine modification
0.47	GO:0051726	regulation of cell cycle
0.44	GO:0035556	intracellular signal transduction
0.42	GO:0051039	positive regulation of transcription involved in meiotic cell cycle
0.42	GO:0061406	positive regulation of transcription from RNA polymerase II promoter in response to glucose starvation

0.67	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0051721	protein phosphatase 2A binding
0.35	GO:0030295	protein kinase activator activity
0.35	GO:0035091	phosphatidylinositol binding
0.35	GO:0097472	cyclin-dependent protein kinase activity
0.33	GO:0051082	unfolded protein binding

0.51	GO:0032154	cleavage furrow
0.48	GO:0005813	centrosome
0.45	GO:0005634	nucleus
0.43	GO:0043233	organelle lumen
0.36	GO:0005737	cytoplasm
0.36	GO:0072687	meiotic spindle
0.34	GO:0016272	prefoldin complex
0.34	GO:0030425	dendrite
0.33	GO:0032133	chromosome passenger complex
0.33	GO:0000939	condensed chromosome inner kinetochore

0.67

GO:0004674

tr|T1G4Q8|T1G4Q8_HELRO
Uncharacterized protein
Search

0.67	GO:2000824	negative regulation of androgen receptor activity
0.65	GO:0035054	embryonic heart tube anterior/posterior pattern specification
0.64	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway
0.63	GO:0003139	secondary heart field specification
0.63	GO:0048318	axial mesoderm development
0.62	GO:0003222	ventricular trabecula myocardium morphogenesis
0.62	GO:0003215	cardiac right ventricle morphogenesis
0.62	GO:0035909	aorta morphogenesis
0.60	GO:0003151	outflow tract morphogenesis
0.60	GO:0001947	heart looping

0.65	GO:0043565	sequence-specific DNA binding
0.64	GO:0070410	co-SMAD binding
0.63	GO:0070412	R-SMAD binding
0.63	GO:0050681	androgen receptor binding
0.63	GO:0043425	bHLH transcription factor binding
0.62	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.60	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.58	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.56	GO:0001104	RNA polymerase II transcription cofactor activity
0.56	GO:0019904	protein domain specific binding

0.65	GO:0032444	activin responsive factor complex
0.55	GO:0000790	nuclear chromatin
0.35	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1G4Q9|T1G4Q9_HELRO
Uncharacterized protein
Search

tr|T1G4R0|T1G4R0_HELRO
Uncharacterized protein
Search

PCSK6

0.73	Proprotein convertase subtilisin/kexin type

0.61	GO:0006508	proteolysis
0.53	GO:0032902	nerve growth factor production
0.51	GO:0007354	zygotic determination of anterior/posterior axis, embryo
0.49	GO:0042445	hormone metabolic process
0.48	GO:0007368	determination of left/right symmetry
0.48	GO:0051604	protein maturation
0.46	GO:0009100	glycoprotein metabolic process
0.44	GO:0032940	secretion by cell
0.43	GO:1905910	negative regulation of dauer entry
0.42	GO:0006518	peptide metabolic process

0.69	GO:0004252	serine-type endopeptidase activity
0.52	GO:0048406	nerve growth factor binding
0.49	GO:0008201	heparin binding
0.38	GO:0005102	receptor binding
0.33	GO:0046872	metal ion binding
0.33	GO:0016301	kinase activity

0.46	GO:0009986	cell surface
0.46	GO:0031012	extracellular matrix
0.46	GO:0005615	extracellular space
0.40	GO:0043025	neuronal cell body
0.37	GO:0002080	acrosomal membrane
0.35	GO:0005796	Golgi lumen
0.34	GO:0030424	axon
0.33	GO:0005783	endoplasmic reticulum
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.69

GO:0004252

tr|T1G4R1|T1G4R1_HELRO
Uncharacterized protein
Search

LHX1

0.94	LIM homeobox protein 1

0.66	GO:0021937	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation
0.65	GO:0021527	spinal cord association neuron differentiation
0.64	GO:0021702	cerebellar Purkinje cell differentiation
0.61	GO:0030900	forebrain development
0.58	GO:2000744	positive regulation of anterior head development
0.57	GO:0097477	lateral motor column neuron migration
0.57	GO:2000768	positive regulation of nephron tubule epithelial cell differentiation
0.57	GO:0035847	uterine epithelium development
0.57	GO:0061205	paramesonephric duct development
0.57	GO:0072049	comma-shaped body morphogenesis

0.65	GO:0043565	sequence-specific DNA binding
0.53	GO:0046872	metal ion binding
0.44	GO:0003700	DNA binding transcription factor activity
0.42	GO:0003714	transcription corepressor activity
0.35	GO:0005515	protein binding
0.35	GO:0035326	enhancer binding
0.34	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.43	GO:0043234	protein complex
0.30	GO:0016020	membrane

tr|T1G4R2|T1G4R2_HELRO
Uncharacterized protein
Search

0.60	Glucose-dependent insulinotropic receptor

0.36	GO:0070647	protein modification by small protein conjugation or removal
0.34	GO:0042073	intraciliary transport
0.34	GO:0060271	cilium assembly
0.33	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:0006508	proteolysis
0.33	GO:0006351	transcription, DNA-templated
0.33	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.33	GO:0016192	vesicle-mediated transport
0.33	GO:0006355	regulation of transcription, DNA-templated
0.32	GO:0006811	ion transport

0.35	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.34	GO:0004842	ubiquitin-protein transferase activity
0.34	GO:0031683	G-protein beta/gamma-subunit complex binding
0.33	GO:0015631	tubulin binding
0.33	GO:0043565	sequence-specific DNA binding
0.33	GO:0003924	GTPase activity
0.33	GO:0008270	zinc ion binding
0.33	GO:0000062	fatty-acyl-CoA binding
0.33	GO:0019001	guanyl nucleotide binding
0.33	GO:0003700	DNA binding transcription factor activity

0.34	GO:0030992	intraciliary transport particle B
0.34	GO:0031514	motile cilium
0.34	GO:0030008	TRAPP complex
0.33	GO:0043231	intracellular membrane-bounded organelle
0.32	GO:0044444	cytoplasmic part
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.32	EC:2.7.7.6	GO:0003899
0.34	KEGG:R03876	GO:0004842

tr|T1G4R3|T1G4R3_HELRO
Uncharacterized protein
Search

0.87	GO:0035509	negative regulation of myosin-light-chain-phosphatase activity
0.87	GO:0035209	pupal development
0.86	GO:0008594	photoreceptor cell morphogenesis
0.86	GO:0016334	establishment or maintenance of polarity of follicular epithelium
0.86	GO:0034334	adherens junction maintenance
0.85	GO:0045494	photoreceptor cell maintenance
0.85	GO:0035088	establishment or maintenance of apical/basal cell polarity
0.85	GO:0001736	establishment of planar polarity

0.88	GO:0032033	myosin II light chain binding
0.85	GO:0005080	protein kinase C binding

0.87	GO:0035003	subapical complex
0.86	GO:0016327	apicolateral plasma membrane
0.82	GO:0016324	apical plasma membrane
0.80	GO:0005912	adherens junction

tr|T1G4R4|T1G4R4_HELRO
Uncharacterized protein
Search

tr|T1G4R5|T1G4R5_HELRO
Uncharacterized protein
Search

tr|T1G4R6|T1G4R6_HELRO
Uncharacterized protein
Search

0.53	Ubiquitin--protein ligase

0.42	GO:0070936	protein K48-linked ubiquitination
0.40	GO:0051865	protein autoubiquitination
0.38	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.37	GO:0035519	protein K29-linked ubiquitination
0.37	GO:0044314	protein K27-linked ubiquitination
0.36	GO:0085020	protein K6-linked ubiquitination
0.36	GO:0070979	protein K11-linked ubiquitination
0.36	GO:0070534	protein K63-linked ubiquitination
0.32	GO:0055114	oxidation-reduction process

0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0061631	ubiquitin conjugating enzyme activity
0.39	GO:0016874	ligase activity
0.38	GO:0031625	ubiquitin protein ligase binding
0.33	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors
0.33	GO:0050660	flavin adenine dinucleotide binding

0.38	GO:0000151	ubiquitin ligase complex
0.35	GO:0043234	protein complex
0.33	GO:0005694	chromosome
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.39

GO:0016874

tr|T1G4R7|T1G4R7_HELRO
Uncharacterized protein
Search

0.56	Microtubule associated serine/threonine kinase 3a

0.63	GO:0006468	protein phosphorylation
0.45	GO:0018209	peptidyl-serine modification
0.41	GO:0007010	cytoskeleton organization
0.41	GO:0035556	intracellular signal transduction
0.39	GO:0016573	histone acetylation

0.70	GO:0004674	protein serine/threonine kinase activity
0.64	GO:0000287	magnesium ion binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0004402	histone acetyltransferase activity

0.35

GO:0005622

intracellular

0.70

GO:0004674

tr|T1G4R8|T1G4R8_HELRO
Uncharacterized protein
Search

0.54

syndetin

0.84	GO:0032456	endocytic recycling
0.81	GO:0042147	retrograde transport, endosome to Golgi
0.65	GO:0015031	protein transport

0.82

GO:0000149

SNARE binding

0.87	GO:1990745	EARP complex
0.67	GO:0070062	extracellular exosome
0.55	GO:0048471	perinuclear region of cytoplasm
0.30	GO:0016020	membrane

tr|T1G4R9|T1G4R9_HELRO
Uncharacterized protein
Search

ADRM1

0.88	Adhesion regulating molecule 1

0.46	GO:0010950	positive regulation of endopeptidase activity
0.43	GO:0043248	proteasome assembly
0.42	GO:0006368	transcription elongation from RNA polymerase II promoter
0.40	GO:0006511	ubiquitin-dependent protein catabolic process
0.34	GO:0007275	multicellular organism development
0.33	GO:0006869	lipid transport

0.48	GO:0061133	endopeptidase activator activity
0.46	GO:0070628	proteasome binding
0.42	GO:0002020	protease binding
0.42	GO:0043130	ubiquitin binding

0.61	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.44	GO:1905369	endopeptidase complex
0.40	GO:0043234	protein complex
0.39	GO:0031974	membrane-enclosed lumen
0.36	GO:0044446	intracellular organelle part
0.36	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1G4S0|T1G4S0_HELRO
Uncharacterized protein
Search

0.72	GO:0000027	ribosomal large subunit assembly
0.41	GO:0006364	rRNA processing
0.36	GO:0009553	embryo sac development
0.35	GO:0048638	regulation of developmental growth
0.34	GO:0009738	abscisic acid-activated signaling pathway
0.33	GO:0045892	negative regulation of transcription, DNA-templated
0.33	GO:0006461	protein complex assembly
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0009059	macromolecule biosynthetic process

0.58	GO:0016887	ATPase activity
0.52	GO:0032559	adenyl ribonucleotide binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0051082	unfolded protein binding
0.32	GO:0019843	rRNA binding
0.32	GO:0003735	structural constituent of ribosome

0.57	GO:0005634	nucleus
0.44	GO:0045111	intermediate filament cytoskeleton
0.44	GO:0030687	preribosome, large subunit precursor
0.41	GO:0005829	cytosol
0.41	GO:0031974	membrane-enclosed lumen
0.39	GO:0044446	intracellular organelle part
0.35	GO:0055044	symplast
0.35	GO:0005911	cell-cell junction
0.34	GO:0009507	chloroplast
0.33	GO:0031975	envelope

0.58

GO:0016887

tr|T1G4S1|T1G4S1_HELRO
Uncharacterized protein
Search

0.53	GO:0007165	signal transduction
0.52	GO:0033563	dorsal/ventral axon guidance
0.52	GO:1901222	regulation of NIK/NF-kappaB signaling
0.49	GO:0006915	apoptotic process
0.42	GO:0034220	ion transmembrane transport
0.40	GO:0040018	positive regulation of multicellular organism growth
0.40	GO:0010171	body morphogenesis
0.38	GO:0006468	protein phosphorylation
0.38	GO:0071804	cellular potassium ion transport
0.35	GO:0006508	proteolysis

0.48	GO:0050839	cell adhesion molecule binding
0.46	GO:0005216	ion channel activity
0.40	GO:0030507	spectrin binding
0.40	GO:0004622	lysophospholipase activity
0.40	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity
0.39	GO:0005509	calcium ion binding
0.38	GO:0004672	protein kinase activity
0.38	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.38	GO:0022832	voltage-gated channel activity
0.38	GO:0015079	potassium ion transmembrane transporter activity

0.50	GO:0016328	lateral plasma membrane
0.39	GO:0008076	voltage-gated potassium channel complex
0.34	GO:0005622	intracellular

0.40

EC:3.1.1.5

GO:0004622

tr|T1G4S2|T1G4S2_HELRO
Uncharacterized protein
Search

0.42	GO:2001253	regulation of histone H3-K36 trimethylation
0.41	GO:0010793	regulation of mRNA export from nucleus
0.39	GO:0050684	regulation of mRNA processing
0.39	GO:0032784	regulation of DNA-templated transcription, elongation
0.35	GO:0061564	axon development
0.35	GO:0035335	peptidyl-tyrosine dephosphorylation
0.34	GO:0042254	ribosome biogenesis

0.35	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.35	GO:0004725	protein tyrosine phosphatase activity
0.34	GO:0005198	structural molecule activity

0.61	GO:0005634	nucleus
0.36	GO:0005883	neurofilament
0.30	GO:0031224	intrinsic component of membrane

0.35

GO:0008138

tr|T1G4S3|T1G4S3_HELRO
Uncharacterized protein
Search

0.61	GO:0043547	positive regulation of GTPase activity
0.61	GO:0007165	signal transduction
0.45	GO:0007480	imaginal disc-derived leg morphogenesis
0.38	GO:0010470	regulation of gastrulation
0.35	GO:0008104	protein localization
0.33	GO:0006364	rRNA processing

0.62	GO:0005096	GTPase activator activity
0.52	GO:0005543	phospholipid binding
0.33	GO:0005515	protein binding

0.37	GO:0030054	cell junction
0.34	GO:0034457	Mpp10 complex
0.34	GO:0005732	small nucleolar ribonucleoprotein complex
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|T1G4S4|T1G4S4_HELRO
Uncharacterized protein
Search

tr|T1G4S5|T1G4S5_HELRO
Uncharacterized protein
Search

CAPN2

0.59	Calpain-1 catalytic subunit

0.61	GO:0006508	proteolysis
0.56	GO:0007586	digestion
0.49	GO:0051493	regulation of cytoskeleton organization
0.43	GO:0071230	cellular response to amino acid stimulus
0.42	GO:0007520	myoblast fusion
0.41	GO:0001824	blastocyst development
0.40	GO:0021785	branchiomotor neuron axon guidance
0.39	GO:0044257	cellular protein catabolic process
0.38	GO:0007420	brain development
0.35	GO:0022617	extracellular matrix disassembly

0.82	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.68	GO:0005509	calcium ion binding
0.34	GO:0046982	protein heterodimerization activity
0.33	GO:0008092	cytoskeletal protein binding
0.32	GO:0030246	carbohydrate binding

0.45	GO:0005622	intracellular
0.43	GO:0031143	pseudopodium
0.41	GO:0045121	membrane raft
0.38	GO:0012505	endomembrane system
0.36	GO:0043228	non-membrane-bounded organelle
0.36	GO:0005886	plasma membrane
0.36	GO:0044422	organelle part
0.36	GO:0043227	membrane-bounded organelle
0.35	GO:0030425	dendrite
0.34	GO:0005925	focal adhesion

tr|T1G4S6|T1G4S6_HELRO
Uncharacterized protein
Search

tr|T1G4S7|T1G4S7_HELRO
Uncharacterized protein
Search

PRKCSH

0.61	Glucosidase II beta-subunit

0.84	GO:0006491	N-glycan processing
0.42	GO:0010977	negative regulation of neuron projection development
0.42	GO:0001889	liver development
0.41	GO:0072001	renal system development
0.40	GO:0016310	phosphorylation
0.40	GO:0001701	in utero embryonic development
0.39	GO:0051291	protein heterooligomerization
0.34	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:0006487	protein N-linked glycosylation
0.33	GO:0006357	regulation of transcription by RNA polymerase II

0.59	GO:0005509	calcium ion binding
0.41	GO:0016301	kinase activity
0.39	GO:0005080	protein kinase C binding
0.38	GO:0044325	ion channel binding
0.38	GO:0051219	phosphoprotein binding
0.37	GO:0003723	RNA binding
0.34	GO:0033919	glucan 1,3-alpha-glucosidase activity
0.34	GO:0004930	G-protein coupled receptor activity
0.33	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.32	GO:0008270	zinc ion binding

0.39	GO:0005783	endoplasmic reticulum
0.34	GO:0043234	protein complex
0.34	GO:0044446	intracellular organelle part
0.33	GO:0005886	plasma membrane
0.32	GO:0005634	nucleus
0.32	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

0.34

EC:3.2.1.84

GO:0033919

tr|T1G4S8|T1G4S8_HELRO
Uncharacterized protein
Search

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0007275	multicellular organism development
0.45	GO:0006366	transcription by RNA polymerase II
0.44	GO:0050764	regulation of phagocytosis
0.44	GO:0007528	neuromuscular junction development
0.42	GO:0048589	developmental growth
0.42	GO:0048468	cell development
0.41	GO:0007601	visual perception

0.64	GO:0043565	sequence-specific DNA binding
0.43	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.43	GO:0001012	RNA polymerase II regulatory region DNA binding
0.41	GO:0003690	double-stranded DNA binding
0.35	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding
0.34	GO:0035326	enhancer binding
0.34	GO:0003682	chromatin binding
0.33	GO:0005230	extracellular ligand-gated ion channel activity
0.33	GO:0099600	transmembrane receptor activity
0.33	GO:0038023	signaling receptor activity

0.61	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|T1G4S9|T1G4S9_HELRO
Uncharacterized protein
Search

0.68	GO:0006278	RNA-dependent DNA biosynthetic process
0.38	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.36	GO:0019236	response to pheromone
0.36	GO:0006360	transcription by RNA polymerase I
0.36	GO:0006383	transcription by RNA polymerase III
0.36	GO:0007018	microtubule-based movement
0.35	GO:0006744	ubiquinone biosynthetic process
0.35	GO:0006366	transcription by RNA polymerase II
0.35	GO:0007186	G-protein coupled receptor signaling pathway
0.35	GO:0006414	translational elongation

0.68	GO:0003964	RNA-directed DNA polymerase activity
0.38	GO:0004519	endonuclease activity
0.36	GO:0001054	RNA polymerase I activity
0.36	GO:0001056	RNA polymerase III activity
0.36	GO:0001055	RNA polymerase II activity
0.36	GO:0003777	microtubule motor activity
0.36	GO:0008017	microtubule binding
0.35	GO:0003779	actin binding
0.35	GO:0008270	zinc ion binding
0.35	GO:0003746	translation elongation factor activity

0.36	GO:0005736	DNA-directed RNA polymerase I complex
0.36	GO:0005666	DNA-directed RNA polymerase III complex
0.36	GO:0016459	myosin complex
0.36	GO:0005665	DNA-directed RNA polymerase II, core complex
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0003964

tr|T1G4T0|T1G4T0_HELRO
Uncharacterized protein
Search

0.10	Putative ATP-dependent RNA helicase DHX33 (inferred by orthology to a human protein)

0.46	GO:0043046	DNA methylation involved in gamete generation
0.46	GO:0034587	piRNA metabolic process
0.46	GO:0010529	negative regulation of transposition
0.46	GO:0007141	male meiosis I
0.45	GO:0007283	spermatogenesis
0.44	GO:0009566	fertilization
0.39	GO:0006396	RNA processing
0.38	GO:0031047	gene silencing by RNA
0.37	GO:0030154	cell differentiation
0.37	GO:0007275	multicellular organism development

0.66	GO:0004386	helicase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0003676	nucleic acid binding
0.44	GO:0046872	metal ion binding
0.42	GO:0008186	RNA-dependent ATPase activity
0.38	GO:0140098	catalytic activity, acting on RNA
0.34	GO:0005267	potassium channel activity
0.33	GO:0004707	MAP kinase activity

0.47	GO:0071547	piP-body
0.39	GO:0005634	nucleus
0.37	GO:0005739	mitochondrion
0.34	GO:0044446	intracellular organelle part
0.33	GO:0005829	cytosol
0.33	GO:0043233	organelle lumen
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0005783	endoplasmic reticulum
0.30	GO:0016021	integral component of membrane

0.33	EC:2.7.11.24	GO:0004707
0.33	KEGG:R00162	GO:0004707

tr|T1G4T1|T1G4T1_HELRO
Uncharacterized protein
Search

CERS5

0.73	Longevity assurance factor 1

0.52	GO:0046513	ceramide biosynthetic process
0.47	GO:0050995	negative regulation of lipid catabolic process
0.46	GO:0032933	SREBP signaling pathway
0.46	GO:0046889	positive regulation of lipid biosynthetic process
0.45	GO:0006641	triglyceride metabolic process
0.36	GO:0030216	keratinocyte differentiation

0.54	GO:0003677	DNA binding
0.53	GO:0050291	sphingosine N-acyltransferase activity

0.59	GO:0005634	nucleus
0.45	GO:0005783	endoplasmic reticulum
0.40	GO:0031967	organelle envelope
0.39	GO:0031090	organelle membrane
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.53

EC:2.3.1.24

GO:0050291

tr|T1G4T2|T1G4T2_HELRO
Uncharacterized protein
Search

0.73	GO:0000027	ribosomal large subunit assembly
0.42	GO:0006364	rRNA processing
0.37	GO:0045892	negative regulation of transcription, DNA-templated
0.35	GO:0006304	DNA modification
0.34	GO:0043414	macromolecule methylation
0.33	GO:0006461	protein complex assembly
0.33	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.33	GO:0005975	carbohydrate metabolic process
0.32	GO:0055085	transmembrane transport

0.58	GO:0016887	ATPase activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0008170	N-methyltransferase activity
0.34	GO:0009007	site-specific DNA-methyltransferase (adenine-specific) activity
0.34	GO:0051082	unfolded protein binding
0.33	GO:0003677	DNA binding
0.33	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.33	GO:0004519	endonuclease activity

0.58	GO:0005634	nucleus
0.47	GO:0045111	intermediate filament cytoskeleton
0.45	GO:0030687	preribosome, large subunit precursor
0.44	GO:0031974	membrane-enclosed lumen
0.44	GO:0005829	cytosol
0.40	GO:0044446	intracellular organelle part
0.34	GO:0044462	external encapsulating structure part
0.33	GO:0019867	outer membrane
0.33	GO:0030313	cell envelope
0.30	GO:0016021	integral component of membrane

0.58

GO:0016887

tr|T1G4T3|T1G4T3_HELRO
Uncharacterized protein
Search

JMJD8

0.97	Jumonji domain-containing 8

tr|T1G4T4|T1G4T4_HELRO
Uncharacterized protein
Search

0.71	GO:0000027	ribosomal large subunit assembly
0.43	GO:0006364	rRNA processing
0.36	GO:0045892	negative regulation of transcription, DNA-templated
0.35	GO:0043248	proteasome assembly
0.33	GO:0006177	GMP biosynthetic process
0.32	GO:0055114	oxidation-reduction process

0.61	GO:0016887	ATPase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005515	protein binding
0.33	GO:0003938	IMP dehydrogenase activity
0.32	GO:0046872	metal ion binding

0.57	GO:0005634	nucleus
0.45	GO:0045111	intermediate filament cytoskeleton
0.44	GO:0030687	preribosome, large subunit precursor
0.44	GO:0031974	membrane-enclosed lumen
0.42	GO:0005829	cytosol
0.40	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.61

GO:0016887

tr|T1G4T5|T1G4T5_HELRO
Uncharacterized protein
Search

KCNJ15

0.90	ATP-sensitive inward rectifier potassium channel 15

0.78	GO:0034765	regulation of ion transmembrane transport
0.71	GO:0006813	potassium ion transport
0.61	GO:0098655	cation transmembrane transport
0.43	GO:0098660	inorganic ion transmembrane transport
0.37	GO:0046662	regulation of oviposition
0.37	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.30	GO:0009987	cellular process

0.84	GO:0005242	inward rectifier potassium channel activity
0.35	GO:0005515	protein binding

0.45	GO:0005887	integral component of plasma membrane
0.37	GO:0043204	perikaryon
0.36	GO:0043005	neuron projection

tr|T1G4T6|T1G4T6_HELRO
Uncharacterized protein
Search

0.59	GO:0006520	cellular amino acid metabolic process
0.36	GO:0043413	macromolecule glycosylation
0.36	GO:0009101	glycoprotein biosynthetic process
0.34	GO:0006464	cellular protein modification process
0.33	GO:0072329	monocarboxylic acid catabolic process
0.33	GO:1901565	organonitrogen compound catabolic process
0.32	GO:0043603	cellular amide metabolic process

0.79	GO:0004067	asparaginase activity
0.37	GO:0004576	oligosaccharyl transferase activity
0.35	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity

0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.79

EC:3.5.1.1

GO:0004067

tr|T1G4T7|T1G4T7_HELRO
Uncharacterized protein
Search

0.62	Mitogen activated protein binding protein interacting protein (Fragment)

0.81	GO:0032008	positive regulation of TOR signaling
0.66	GO:0065009	regulation of molecular function

0.81	GO:0032947	protein complex scaffold activity
0.75	GO:0005085	guanyl-nucleotide exchange factor activity

tr|T1G4T8|T1G4T8_HELRO
Uncharacterized protein
Search

0.50	High-affinity choline transporter

0.55	GO:0055085	transmembrane transport
0.47	GO:0008292	acetylcholine biosynthetic process
0.46	GO:0015871	choline transport
0.38	GO:0007271	synaptic transmission, cholinergic
0.38	GO:0007274	neuromuscular synaptic transmission
0.36	GO:0006814	sodium ion transport
0.33	GO:0006865	amino acid transport
0.33	GO:0006030	chitin metabolic process
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.57	GO:0022857	transmembrane transporter activity
0.44	GO:0005326	neurotransmitter transporter activity
0.44	GO:0033265	choline binding
0.33	GO:0005509	calcium ion binding
0.33	GO:0008061	chitin binding
0.33	GO:0003700	DNA binding transcription factor activity

0.42	GO:0043025	neuronal cell body
0.41	GO:0045202	synapse
0.40	GO:0030424	axon
0.39	GO:0070382	exocytic vesicle
0.39	GO:0005887	integral component of plasma membrane
0.35	GO:0030425	dendrite
0.32	GO:0005576	extracellular region

tr|T1G4T9|T1G4T9_HELRO
Uncharacterized protein
Search

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.50	GO:0021536	diencephalon development
0.50	GO:0021761	limbic system development
0.45	GO:0030878	thyroid gland development
0.44	GO:0010719	negative regulation of epithelial to mesenchymal transition
0.44	GO:0060441	epithelial tube branching involved in lung morphogenesis
0.44	GO:0048857	neural nucleus development
0.44	GO:0060486	Clara cell differentiation

0.65	GO:0043565	sequence-specific DNA binding
0.45	GO:0044213	intronic transcription regulatory region DNA binding
0.42	GO:0001047	core promoter binding
0.42	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.41	GO:0001012	RNA polymerase II regulatory region DNA binding
0.41	GO:0003690	double-stranded DNA binding
0.40	GO:0019899	enzyme binding
0.34	GO:0008134	transcription factor binding
0.34	GO:0004000	adenosine deaminase activity

0.61	GO:0005634	nucleus
0.40	GO:0005667	transcription factor complex
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.34

EC:3.5.4.4

GO:0004000

tr|T1G4U0|T1G4U0_HELRO
Lon protease homolog
Search

LONP1

0.71	Lon protease homolog, mitochondrial

0.77	GO:0070407	oxidation-dependent protein catabolic process
0.75	GO:0090296	regulation of mitochondrial DNA replication
0.74	GO:0006515	protein quality control for misfolded or incompletely synthesized proteins
0.72	GO:0051131	chaperone-mediated protein complex assembly
0.66	GO:0034599	cellular response to oxidative stress
0.50	GO:0001666	response to hypoxia
0.49	GO:0007005	mitochondrion organization
0.48	GO:0051260	protein homooligomerization
0.39	GO:0010044	response to aluminum ion
0.37	GO:0007568	aging

0.73	GO:0004176	ATP-dependent peptidase activity
0.66	GO:0004252	serine-type endopeptidase activity
0.58	GO:0043565	sequence-specific DNA binding
0.55	GO:0001018	mitochondrial promoter sequence-specific DNA binding
0.53	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0051880	G-quadruplex DNA binding
0.52	GO:0070182	DNA polymerase binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0003727	single-stranded RNA binding

0.67	GO:0005759	mitochondrial matrix
0.47	GO:0009295	nucleoid
0.46	GO:0005654	nucleoplasm
0.45	GO:0005829	cytosol
0.41	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

0.66

GO:0004252

tr|T1G4U1|T1G4U1_HELRO
Uncharacterized protein
Search

0.10	Serine/threonine-protein kinase LMTK1

0.63	GO:0006468	protein phosphorylation
0.60	GO:0018212	peptidyl-tyrosine modification
0.47	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.43	GO:0016204	determination of muscle attachment site
0.43	GO:0009888	tissue development
0.43	GO:0061643	chemorepulsion of axon
0.42	GO:0070983	dendrite guidance
0.42	GO:0016199	axon midline choice point recognition
0.42	GO:0008355	olfactory learning
0.41	GO:0007435	salivary gland morphogenesis

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0004888	transmembrane signaling receptor activity
0.41	GO:0017147	Wnt-protein binding
0.40	GO:0019899	enzyme binding
0.39	GO:0042803	protein homodimerization activity
0.39	GO:0046982	protein heterodimerization activity
0.39	GO:0005509	calcium ion binding

0.40	GO:0030425	dendrite
0.40	GO:0030424	axon
0.40	GO:0043235	receptor complex
0.38	GO:0005887	integral component of plasma membrane
0.37	GO:0097517	contractile actin filament bundle
0.37	GO:0042641	actomyosin
0.36	GO:0005773	vacuole
0.35	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0005576	extracellular region

0.34

GO:0004383

tr|T1G4U2|T1G4U2_HELRO
Uncharacterized protein
Search

0.14	craniofacial development protein 2-like

0.69	GO:0015074	DNA integration
0.65	GO:0006310	DNA recombination

0.55

GO:0003677

DNA binding

tr|T1G4U3|T1G4U3_HELRO
Guanylate cyclase
Search

0.47	Guanylate cyclase

0.82	GO:0006182	cGMP biosynthetic process
0.63	GO:0006468	protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.45	GO:0045792	negative regulation of cell size
0.43	GO:0007030	Golgi organization
0.43	GO:0045931	positive regulation of mitotic cell cycle
0.43	GO:0008284	positive regulation of cell proliferation
0.35	GO:0060038	cardiac muscle cell proliferation
0.35	GO:0007020	microtubule nucleation
0.34	GO:0018212	peptidyl-tyrosine modification

0.82	GO:0004383	guanylate cyclase activity
0.63	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0004016	adenylate cyclase activity
0.36	GO:0004872	receptor activity
0.35	GO:0043015	gamma-tubulin binding
0.34	GO:0051287	NAD binding
0.34	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

0.45	GO:0005622	intracellular
0.37	GO:0005886	plasma membrane
0.37	GO:0043234	protein complex
0.34	GO:0009986	cell surface
0.34	GO:0098552	side of membrane
0.33	GO:0043228	non-membrane-bounded organelle
0.33	GO:0044422	organelle part
0.30	GO:0016021	integral component of membrane

0.82

GO:0004383

tr|T1G4U4|T1G4U4_HELRO
Uncharacterized protein
Search

0.54	CCR4-NOT transcription complex subunit 4

0.47	GO:0051865	protein autoubiquitination
0.43	GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
0.37	GO:0006457	protein folding
0.35	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
0.32	GO:0006351	transcription, DNA-templated
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.59	GO:0003723	RNA binding
0.54	GO:0046872	metal ion binding
0.45	GO:0004842	ubiquitin-protein transferase activity
0.37	GO:0051082	unfolded protein binding
0.32	GO:0003677	DNA binding

0.48	GO:0030014	CCR4-NOT complex
0.38	GO:0016272	prefoldin complex
0.34	GO:0005634	nucleus
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.45

GO:0004842

tr|T1G4U5|T1G4U5_HELRO
Uncharacterized protein
Search

0.71

GO:0007186

G-protein coupled receptor signaling pathway

0.72

GO:0004930

G-protein coupled receptor activity

0.30

GO:0044425

membrane part

tr|T1G4U6|T1G4U6_HELRO
Uncharacterized protein
Search

0.10	GATA transcription factor (Fragment)

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.44	GO:1902680	positive regulation of RNA biosynthetic process
0.44	GO:0007510	cardioblast cell fate determination
0.44	GO:0048534	hematopoietic or lymphoid organ development
0.43	GO:0061320	pericardial nephrocyte differentiation
0.43	GO:0002805	regulation of antimicrobial peptide biosynthetic process
0.42	GO:0022416	chaeta development
0.42	GO:0060047	heart contraction

0.65	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.44	GO:0001085	RNA polymerase II transcription factor binding
0.42	GO:0070491	repressing transcription factor binding
0.41	GO:0044212	transcription regulatory region DNA binding
0.40	GO:0003690	double-stranded DNA binding
0.40	GO:0046982	protein heterodimerization activity
0.39	GO:0003682	chromatin binding
0.34	GO:0003707	steroid hormone receptor activity

0.45	GO:0005634	nucleus
0.38	GO:0005667	transcription factor complex

tr|T1G4U7|T1G4U7_HELRO
Ribosomal protein S6 kinase
Search

0.74	Ribosomal protein S6 kinase alpha-5

0.62	GO:0006468	protein phosphorylation
0.60	GO:0035556	intracellular signal transduction
0.54	GO:0033129	positive regulation of histone phosphorylation
0.52	GO:0070498	interleukin-1-mediated signaling pathway
0.52	GO:0035066	positive regulation of histone acetylation
0.49	GO:0018209	peptidyl-serine modification
0.47	GO:0045944	positive regulation of transcription by RNA polymerase II
0.47	GO:0016570	histone modification
0.44	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.40	GO:0045892	negative regulation of transcription, DNA-templated

0.68	GO:0004674	protein serine/threonine kinase activity
0.61	GO:0000287	magnesium ion binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding

0.46	GO:0005654	nucleoplasm
0.42	GO:0005829	cytosol
0.34	GO:0005840	ribosome

0.68

GO:0004674

tr|T1G4U8|T1G4U8_HELRO
Uncharacterized protein
Search

0.42	GO:2001253	regulation of histone H3-K36 trimethylation
0.41	GO:0010793	regulation of mRNA export from nucleus
0.39	GO:0050684	regulation of mRNA processing
0.39	GO:0032784	regulation of DNA-templated transcription, elongation
0.35	GO:0061564	axon development
0.34	GO:0035335	peptidyl-tyrosine dephosphorylation
0.34	GO:0042254	ribosome biogenesis

0.35	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.34	GO:0004725	protein tyrosine phosphatase activity
0.34	GO:0005198	structural molecule activity

0.61	GO:0005634	nucleus
0.36	GO:0005883	neurofilament
0.30	GO:0031224	intrinsic component of membrane

0.35

GO:0008138

tr|T1G4U9|T1G4U9_HELRO
Uncharacterized protein
Search

PIM2

0.53	LOW QUALITY PROTEIN: serine/threonine-protein kinase pim-2

0.71	GO:0043066	negative regulation of apoptotic process
0.63	GO:0006468	protein phosphorylation
0.51	GO:0008637	apoptotic mitochondrial changes
0.50	GO:0016239	positive regulation of macroautophagy
0.50	GO:0032091	negative regulation of protein binding
0.50	GO:0000082	G1/S transition of mitotic cell cycle
0.50	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.49	GO:0050821	protein stabilization
0.48	GO:0008285	negative regulation of cell proliferation
0.48	GO:0009615	response to virus

0.66	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0005249	voltage-gated potassium channel activity
0.35	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.34	GO:0005515	protein binding
0.33	GO:0005351	sugar:proton symporter activity
0.33	GO:0003676	nucleic acid binding

0.37	GO:0005737	cytoplasm
0.36	GO:0008076	voltage-gated potassium channel complex
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0031984	organelle subcompartment
0.33	GO:0012505	endomembrane system
0.32	GO:0043231	intracellular membrane-bounded organelle

0.66

GO:0004674

tr|T1G4V0|T1G4V0_HELRO
Non-specific serine/threonine protein kinase
Search

0.59	Non-specific serine/threonine protein kinase

0.63	GO:0006468	protein phosphorylation
0.49	GO:0032007	negative regulation of TOR signaling
0.47	GO:0009267	cellular response to starvation
0.45	GO:0042595	behavioral response to starvation
0.45	GO:0030730	sequestering of triglyceride
0.45	GO:0042331	phototaxis
0.44	GO:0045792	negative regulation of cell size
0.44	GO:0044058	regulation of digestive system process
0.44	GO:0018209	peptidyl-serine modification
0.44	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity

0.70	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0035173	histone kinase activity
0.42	GO:0060089	molecular transducer activity
0.39	GO:0050405	[acetyl-CoA carboxylase] kinase activity
0.39	GO:0047322	[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity
0.38	GO:0003682	chromatin binding

0.45	GO:0031588	nucleotide-activated protein kinase complex
0.41	GO:0005634	nucleus
0.37	GO:0005794	Golgi apparatus
0.36	GO:0070013	intracellular organelle lumen
0.35	GO:0044446	intracellular organelle part
0.35	GO:0098588	bounding membrane of organelle
0.34	GO:0016324	apical plasma membrane
0.33	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.70

GO:0004674

tr|T1G4V1|T1G4V1_HELRO
Uncharacterized protein
Search

0.32	Urea active transporter

0.81	GO:0071918	urea transmembrane transport
0.48	GO:0015847	putrescine transport
0.48	GO:1903711	spermidine transmembrane transport
0.46	GO:0043419	urea catabolic process
0.38	GO:0006950	response to stress
0.33	GO:0043562	cellular response to nitrogen levels
0.32	GO:0044271	cellular nitrogen compound biosynthetic process

0.81	GO:0015204	urea transmembrane transporter activity
0.48	GO:0015489	putrescine transmembrane transporter activity
0.48	GO:0015606	spermidine transmembrane transporter activity
0.39	GO:0015293	symporter activity
0.32	GO:0003676	nucleic acid binding

0.40	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1G4V2|T1G4V2_HELRO
Uncharacterized protein
Search

0.65	Zinc finger MYM-type protein (Fragment)

0.37	GO:0006357	regulation of transcription by RNA polymerase II
0.35	GO:0016310	phosphorylation
0.33	GO:0007275	multicellular organism development
0.32	GO:0015074	DNA integration
0.32	GO:0008299	isoprenoid biosynthetic process
0.32	GO:0036211	protein modification process
0.32	GO:0005975	carbohydrate metabolic process
0.32	GO:0044267	cellular protein metabolic process

0.68	GO:0046983	protein dimerization activity
0.37	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.36	GO:0016301	kinase activity
0.34	GO:0003677	DNA binding
0.33	GO:0004650	polygalacturonase activity
0.32	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.32	GO:0140096	catalytic activity, acting on a protein
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0046872	metal ion binding
0.32	GO:0008144	drug binding

0.37	GO:0005654	nucleoplasm
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.33

EC:3.2.1.15

GO:0004650

tr|T1G4V3|T1G4V3_HELRO
Uncharacterized protein
Search

0.64	GO:0000027	ribosomal large subunit assembly
0.41	GO:0043248	proteasome assembly
0.38	GO:0006364	rRNA processing

0.61	GO:0016887	ATPase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.52	GO:0005634	nucleus
0.40	GO:0030687	preribosome, large subunit precursor

0.61

GO:0016887

tr|T1G4V4|T1G4V4_HELRO
Uncharacterized protein
Search

0.57	EH domain-binding protein 1 (Fragment)

0.41	GO:0006897	endocytosis
0.40	GO:0015031	protein transport

0.36

GO:0005515

protein binding

0.68	GO:0005829	cytosol
0.55	GO:0005886	plasma membrane
0.42	GO:0005768	endosome
0.30	GO:0044425	membrane part

tr|T1G4V5|T1G4V5_HELRO
Uncharacterized protein
Search

tr|T1G4V6|T1G4V6_HELRO
Uncharacterized protein
Search

tr|T1G4V7|T1G4V7_HELRO
Uncharacterized protein
Search

COASY

0.40	Pantetheine-phosphate adenylyltransferase activity; dephospho-CoA kinase activity

0.75	GO:0015937	coenzyme A biosynthetic process
0.57	GO:0016310	phosphorylation
0.33	GO:0055114	oxidation-reduction process
0.33	GO:0097359	UDP-glucosylation
0.32	GO:0006486	protein glycosylation
0.32	GO:0006284	base-excision repair
0.32	GO:0006289	nucleotide-excision repair
0.32	GO:0006355	regulation of transcription, DNA-templated

0.79	GO:0004140	dephospho-CoA kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0004595	pantetheine-phosphate adenylyltransferase activity
0.36	GO:0046983	protein dimerization activity
0.33	GO:0016491	oxidoreductase activity
0.33	GO:0003980	UDP-glucose:glycoprotein glucosyltransferase activity
0.32	GO:0008534	oxidized purine nucleobase lesion DNA N-glycosylase activity
0.32	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity

0.44	GO:0005759	mitochondrial matrix
0.42	GO:0005654	nucleoplasm
0.42	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.34	GO:0005741	mitochondrial outer membrane
0.30	GO:0031224	intrinsic component of membrane

0.79	EC:2.7.1.24	GO:0004140
0.79	KEGG:R00130	GO:0004140

tr|T1G4V8|T1G4V8_HELRO
Uncharacterized protein
Search

0.77	JNK-interacting protein 1 (Fragment)

0.77	GO:0048491	retrograde synaptic vesicle transport
0.73	GO:0019896	axonal transport of mitochondrion
0.73	GO:2000331	regulation of terminal button organization
0.72	GO:0048490	anterograde synaptic vesicle transport
0.69	GO:0046328	regulation of JNK cascade
0.65	GO:0043410	positive regulation of MAPK cascade
0.49	GO:0016310	phosphorylation
0.45	GO:0031098	stress-activated protein kinase signaling cascade
0.42	GO:0007275	multicellular organism development
0.40	GO:0046958	nonassociative learning

0.73	GO:0005078	MAP-kinase scaffold activity
0.70	GO:0019894	kinesin binding
0.66	GO:0019901	protein kinase binding
0.61	GO:0042802	identical protein binding
0.49	GO:0016301	kinase activity

0.70	GO:1904115	axon cytoplasm
0.39	GO:0014069	postsynaptic density
0.38	GO:0043025	neuronal cell body
0.30	GO:0016020	membrane

tr|T1G4V9|T1G4V9_HELRO
Uncharacterized protein
Search

0.62	GO:0090324	negative regulation of oxidative phosphorylation
0.62	GO:0045821	positive regulation of glycolytic process
0.61	GO:0045723	positive regulation of fatty acid biosynthetic process
0.60	GO:0033137	negative regulation of peptidyl-serine phosphorylation
0.60	GO:0010255	glucose mediated signaling pathway
0.60	GO:0071157	negative regulation of cell cycle arrest
0.55	GO:0008284	positive regulation of cell proliferation
0.55	GO:0000122	negative regulation of transcription by RNA polymerase II
0.53	GO:0045944	positive regulation of transcription by RNA polymerase II

0.68	GO:0046983	protein dimerization activity
0.58	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.56	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.52	GO:0008134	transcription factor binding

0.53	GO:0005667	transcription factor complex
0.50	GO:0005829	cytosol
0.46	GO:0005634	nucleus

tr|T1G4W0|T1G4W0_HELRO
Uncharacterized protein
Search

0.10	Tripartite motif-containing 3b (Fragment)

0.42	GO:0060215	primitive hemopoiesis
0.41	GO:0030099	myeloid cell differentiation
0.37	GO:0016567	protein ubiquitination
0.32	GO:0045454	cell redox homeostasis

0.61	GO:0008270	zinc ion binding
0.37	GO:0004842	ubiquitin-protein transferase activity

0.44	GO:0005622	intracellular
0.30	GO:0031224	intrinsic component of membrane

0.37

GO:0004842

tr|T1G4W1|T1G4W1_HELRO
Uncharacterized protein
Search

PRKG1

0.73	cGMP-dependent protein kinase

0.63	GO:0006468	protein phosphorylation
0.52	GO:0090331	negative regulation of platelet aggregation
0.52	GO:1904753	negative regulation of vascular associated smooth muscle cell migration
0.51	GO:1904706	negative regulation of vascular smooth muscle cell proliferation
0.49	GO:0060087	relaxation of vascular smooth muscle
0.48	GO:0019934	cGMP-mediated signaling
0.47	GO:0043087	regulation of GTPase activity
0.46	GO:0001764	neuron migration
0.46	GO:0016358	dendrite development
0.45	GO:0030900	forebrain development

0.85	GO:0004692	cGMP-dependent protein kinase activity
0.73	GO:0030553	cGMP binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.50	GO:0005246	calcium channel regulator activity
0.37	GO:0042802	identical protein binding
0.35	GO:0048273	mitogen-activated protein kinase p38 binding
0.33	GO:0046983	protein dimerization activity

0.42	GO:0005794	Golgi apparatus
0.39	GO:0005886	plasma membrane
0.35	GO:0005829	cytosol
0.34	GO:0001669	acrosomal vesicle
0.33	GO:0005654	nucleoplasm

0.85

EC:2.7.11.12

GO:0004692

tr|T1G4W2|T1G4W2_HELRO
Uncharacterized protein
Search

tr|T1G4W3|T1G4W3_HELRO
Uncharacterized protein
Search

HS3ST1

0.55	Heparan sulfate glucosamine 3-O-sulfotransferase 5

0.41	GO:0015012	heparan sulfate proteoglycan biosynthetic process
0.39	GO:0055003	cardiac myofibril assembly
0.38	GO:0045214	sarcomere organization
0.38	GO:0060047	heart contraction
0.33	GO:0000395	mRNA 5'-splice site recognition
0.33	GO:0000387	spliceosomal snRNP assembly

0.78	GO:0008146	sulfotransferase activity
0.33	GO:0030619	U1 snRNA binding
0.33	GO:0003729	mRNA binding
0.32	GO:0008270	zinc ion binding
0.32	GO:0016787	hydrolase activity

0.35	GO:0005796	Golgi lumen
0.33	GO:0000243	commitment complex
0.33	GO:0071004	U2-type prespliceosome
0.33	GO:0005685	U1 snRNP
0.30	GO:0016020	membrane

0.78

GO:0008146

tr|T1G4W4|T1G4W4_HELRO
Uncharacterized protein
Search

0.92	Non-alpha nicotinic acetylcholine receptor subunit

0.79	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.45	GO:0007271	synaptic transmission, cholinergic

0.83	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0099600	transmembrane receptor activity
0.34	GO:0008146	sulfotransferase activity

0.79	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.35	GO:0005892	acetylcholine-gated channel complex

0.34

GO:0008146

tr|T1G4W5|T1G4W5_HELRO
Uncharacterized protein
Search

0.65	Inward rectifier potassium channel

0.78	GO:0034765	regulation of ion transmembrane transport
0.71	GO:0006813	potassium ion transport
0.61	GO:0098655	cation transmembrane transport
0.37	GO:0045475	locomotor rhythm
0.37	GO:0035220	wing disc development
0.36	GO:0042391	regulation of membrane potential
0.36	GO:0098660	inorganic ion transmembrane transport
0.34	GO:0046662	regulation of oviposition
0.34	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.34	GO:0006836	neurotransmitter transport

0.84	GO:0005242	inward rectifier potassium channel activity
0.34	GO:0005328	neurotransmitter:sodium symporter activity
0.32	GO:0008270	zinc ion binding
0.32	GO:0003676	nucleic acid binding

0.36	GO:0005887	integral component of plasma membrane
0.34	GO:0043025	neuronal cell body
0.34	GO:0043005	neuron projection
0.33	GO:0005840	ribosome

tr|T1G4W6|T1G4W6_HELRO
Uncharacterized protein
Search

PLS3

0.67	Fimbrin (inferred by orthology to a D. melanogaster protein)

0.50	GO:1902896	terminal web assembly
0.50	GO:0001951	intestinal D-glucose absorption
0.50	GO:0051639	actin filament network formation
0.50	GO:0032532	regulation of microvillus length
0.50	GO:0051764	actin crosslink formation
0.48	GO:0040018	positive regulation of multicellular organism growth
0.48	GO:1903078	positive regulation of protein localization to plasma membrane
0.48	GO:0051017	actin filament bundle assembly
0.43	GO:0060348	bone development
0.36	GO:0030033	microvillus assembly

0.74	GO:0003779	actin binding
0.65	GO:0005509	calcium ion binding
0.58	GO:0032403	protein complex binding
0.34	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity
0.34	GO:0005200	structural constituent of cytoskeleton
0.33	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.32	GO:0003677	DNA binding

0.50	GO:1990357	terminal web
0.48	GO:0032432	actin filament bundle
0.48	GO:0005884	actin filament
0.47	GO:0005903	brush border
0.39	GO:0005829	cytosol
0.37	GO:0005886	plasma membrane
0.35	GO:0070062	extracellular exosome
0.34	GO:0045335	phagocytic vesicle
0.34	GO:0030027	lamellipodium
0.30	GO:0031224	intrinsic component of membrane

0.34	EC:2.4.2.19	GO:0004514
0.34	KEGG:R03348	GO:0004514

tr|T1G4W7|T1G4W7_HELRO
Uncharacterized protein
Search

0.73	DnaJ like protein subfamily B member 1

0.69	GO:0006457	protein folding
0.47	GO:0097201	negative regulation of transcription from RNA polymerase II promoter in response to stress
0.47	GO:0090084	negative regulation of inclusion body assembly
0.45	GO:0032781	positive regulation of ATPase activity
0.40	GO:1904158	axonemal central apparatus assembly
0.38	GO:0002088	lens development in camera-type eye
0.33	GO:0045454	cell redox homeostasis

0.71	GO:0051082	unfolded protein binding
0.46	GO:0001106	RNA polymerase II transcription corepressor activity
0.46	GO:0030544	Hsp70 protein binding
0.46	GO:0051117	ATPase binding
0.45	GO:0001671	ATPase activator activity
0.44	GO:0045296	cadherin binding
0.43	GO:0051087	chaperone binding
0.31	GO:0046872	metal ion binding

0.41	GO:0005829	cytosol
0.40	GO:0097224	sperm connecting piece
0.39	GO:0005634	nucleus
0.38	GO:0005930	axoneme
0.35	GO:0070062	extracellular exosome
0.34	GO:0014069	postsynaptic density
0.34	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

tr|T1G4W8|T1G4W8_HELRO
Uncharacterized protein
Search

MTX2

0.89	Metaxin-2 homolog (inferred by orthology to a C. elegans protein)

0.78	GO:0006626	protein targeting to mitochondrion
0.34	GO:0032781	positive regulation of ATPase activity
0.33	GO:0097428	protein maturation by iron-sulfur cluster transfer
0.33	GO:0051259	protein oligomerization
0.32	GO:0006260	DNA replication

0.34	GO:0001671	ATPase activator activity
0.34	GO:0005515	protein binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0003676	nucleic acid binding
0.33	GO:0004386	helicase activity

0.77	GO:0005741	mitochondrial outer membrane
0.46	GO:0005730	nucleolus
0.30	GO:0031224	intrinsic component of membrane

tr|T1G4W9|T1G4W9_HELRO
Uncharacterized protein
Search

0.69	GO:0007623	circadian rhythm
0.64	GO:0006366	transcription by RNA polymerase II
0.62	GO:0006955	immune response
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0071353	cellular response to interleukin-4
0.49	GO:0051253	negative regulation of RNA metabolic process
0.49	GO:0010558	negative regulation of macromolecule biosynthetic process
0.49	GO:0031327	negative regulation of cellular biosynthetic process

0.61	GO:0003700	DNA binding transcription factor activity
0.51	GO:0001012	RNA polymerase II regulatory region DNA binding
0.51	GO:0000976	transcription regulatory region sequence-specific DNA binding
0.39	GO:0035326	enhancer binding
0.34	GO:0005515	protein binding
0.34	GO:0003714	transcription corepressor activity
0.33	GO:0008168	methyltransferase activity

0.56	GO:0005634	nucleus
0.33	GO:0005737	cytoplasm

0.33

GO:0008168

tr|T1G4X0|T1G4X0_HELRO
Uncharacterized protein
Search

tr|T1G4X1|T1G4X1_HELRO
Uncharacterized protein
Search

NME5

0.88	Nucleoside diphosphate kinase like protein 5

0.78	GO:0006228	UTP biosynthetic process
0.78	GO:0006183	GTP biosynthetic process
0.74	GO:0046036	CTP metabolic process
0.69	GO:0006165	nucleoside diphosphate phosphorylation
0.65	GO:0048515	spermatid differentiation
0.58	GO:1902176	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
0.57	GO:0003351	epithelial cilium movement
0.56	GO:0021591	ventricular system development
0.52	GO:0007281	germ cell development
0.52	GO:0060271	cilium assembly

0.78	GO:0004550	nucleoside diphosphate kinase activity
0.44	GO:0032559	adenyl ribonucleotide binding
0.43	GO:0008144	drug binding
0.43	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0046872	metal ion binding
0.34	GO:0004127	cytidylate kinase activity
0.34	GO:0009041	uridylate kinase activity
0.33	GO:0005515	protein binding
0.32	GO:0004519	endonuclease activity
0.32	GO:0003676	nucleic acid binding

0.55	GO:0036126	sperm flagellum
0.40	GO:0005737	cytoplasm
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.78

EC:2.7.4.6

GO:0004550

tr|T1G4X2|T1G4X2_HELRO
Uncharacterized protein
Search

ABCA3

0.76	ATP-binding cassette sub-family A member 3

0.55	GO:0055085	transmembrane transport
0.43	GO:0006869	lipid transport
0.39	GO:0038027	apolipoprotein A-I-mediated signaling pathway
0.39	GO:0034380	high-density lipoprotein particle assembly
0.37	GO:0097035	regulation of membrane lipid distribution
0.37	GO:0032374	regulation of cholesterol transport
0.37	GO:0015748	organophosphate ester transport
0.37	GO:0015850	organic hydroxy compound transport
0.37	GO:0048545	response to steroid hormone
0.36	GO:1902995	positive regulation of phospholipid efflux

0.66	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.40	GO:0090556	phosphatidylserine-translocating ATPase activity
0.40	GO:0034188	apolipoprotein A-I receptor activity
0.39	GO:0090554	phosphatidylcholine-translocating ATPase activity
0.35	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity
0.34	GO:0005516	calmodulin binding

0.44	GO:0097208	alveolar lamellar body
0.40	GO:0097232	lamellar body membrane
0.38	GO:0043231	intracellular membrane-bounded organelle
0.37	GO:0005886	plasma membrane
0.36	GO:0030054	cell junction
0.35	GO:0005768	endosome
0.35	GO:0005615	extracellular space
0.34	GO:0001726	ruffle
0.34	GO:0045177	apical part of cell
0.34	GO:0120038	plasma membrane bounded cell projection part

0.35	EC:2.4.2.19	GO:0004514
0.35	KEGG:R03348	GO:0004514

tr|T1G4X3|T1G4X3_HELRO
Uncharacterized protein
Search

R3HCC1L

0.77	Growth inhibition and differentiation-related protein 88

0.34	GO:0106004	tRNA (guanine-N7)-methylation
0.34	GO:0000387	spliceosomal snRNP assembly

0.49	GO:0003676	nucleic acid binding
0.34	GO:0008176	tRNA (guanine-N7-)-methyltransferase activity
0.33	GO:0005515	protein binding

0.48	GO:0035145	exon-exon junction complex
0.33	GO:0005681	spliceosomal complex

0.34

EC:2.1.1.33

GO:0008176

tr|T1G4X4|T1G4X4_HELRO
Uncharacterized protein
Search

NUDT12

0.58	Nudix (Nucleoside diphosphate linked moiety X)-type motif 12

0.63	GO:0019677	NAD catabolic process
0.58	GO:0006742	NADP catabolic process

0.59	GO:0000210	NAD+ diphosphatase activity
0.58	GO:0035529	NADH pyrophosphatase activity
0.53	GO:0046872	metal ion binding

0.53	GO:0042579	microbody
0.46	GO:0005634	nucleus

0.59	EC:3.6.1.22	GO:0000210
0.58	KEGG:R00103	GO:0035529

tr|T1G4X5|T1G4X5_HELRO
Uncharacterized protein
Search

0.56	Proline dehydrogenase

0.79	GO:0006562	proline catabolic process
0.53	GO:0055114	oxidation-reduction process
0.43	GO:0006536	glutamate metabolic process
0.36	GO:0010942	positive regulation of cell death
0.35	GO:0019470	4-hydroxyproline catabolic process
0.35	GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress

0.80	GO:0004657	proline dehydrogenase activity
0.43	GO:0071949	FAD binding
0.43	GO:0005509	calcium ion binding
0.36	GO:0016597	amino acid binding

0.42	GO:0005739	mitochondrion
0.40	GO:0019866	organelle inner membrane
0.35	GO:0031974	membrane-enclosed lumen

0.80

EC:1.5.99.8

GO:0004657

tr|T1G4X6|T1G4X6_HELRO
Uncharacterized protein
Search

0.81	Nicotinic acetylcholine receptor

0.79	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.40	GO:0030431	sleep
0.38	GO:0007271	synaptic transmission, cholinergic
0.38	GO:0006812	cation transport
0.38	GO:0035094	response to nicotine
0.37	GO:0007274	neuromuscular synaptic transmission
0.34	GO:0017085	response to insecticide

0.82	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0099600	transmembrane receptor activity
0.38	GO:0042166	acetylcholine binding
0.32	GO:0003676	nucleic acid binding

0.79	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.49	GO:0005892	acetylcholine-gated channel complex

tr|T1G4X7|T1G4X7_HELRO
Uncharacterized protein
Search

WASHC4

0.95	WASH complex subunit 7

0.54	GO:0016197	endosomal transport
0.50	GO:0007032	endosome organization
0.34	GO:0015031	protein transport

0.84	GO:0071203	WASH complex
0.53	GO:0005768	endosome
0.48	GO:0005654	nucleoplasm
0.38	GO:0031083	BLOC-1 complex
0.30	GO:0016020	membrane

tr|T1G4X8|T1G4X8_HELRO
Uncharacterized protein
Search

tr|T1G4X9|T1G4X9_HELRO
Uncharacterized protein
Search

0.73	Mitochondrial import inner membrane translocase subunit Tim9

0.65	GO:0015031	protein transport
0.42	GO:0090151	establishment of protein localization to mitochondrial membrane
0.42	GO:0007007	inner mitochondrial membrane organization
0.42	GO:1990542	mitochondrial transmembrane transport
0.39	GO:0046907	intracellular transport
0.37	GO:0009058	biosynthetic process
0.33	GO:0006518	peptide metabolic process
0.33	GO:0044267	cellular protein metabolic process
0.33	GO:0010467	gene expression

0.54	GO:0046872	metal ion binding
0.43	GO:0030170	pyridoxal phosphate binding
0.40	GO:0008565	protein transporter activity
0.36	GO:1904680	peptide transmembrane transporter activity
0.36	GO:0022884	macromolecule transmembrane transporter activity
0.36	GO:0033220	amide-transporting ATPase activity
0.34	GO:0008483	transaminase activity
0.34	GO:0003735	structural constituent of ribosome

0.61	GO:0005739	mitochondrion
0.42	GO:0031970	organelle envelope lumen
0.39	GO:1990351	transporter complex
0.38	GO:0098796	membrane protein complex
0.38	GO:0019866	organelle inner membrane
0.33	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.34

EC:2.6.1

GO:0008483

tr|T1G4Y0|T1G4Y0_HELRO
Uncharacterized protein
Search

PHKG1

0.51	Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart

0.64	GO:0005978	glycogen biosynthetic process
0.63	GO:0006468	protein phosphorylation
0.41	GO:0001525	angiogenesis
0.39	GO:0007165	signal transduction
0.38	GO:0018209	peptidyl-serine modification
0.38	GO:0018210	peptidyl-threonine modification
0.37	GO:0009934	regulation of meristem structural organization
0.36	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.35	GO:0032870	cellular response to hormone stimulus
0.34	GO:0016570	histone modification

0.73	GO:0004689	phosphorylase kinase activity
0.66	GO:0005516	calmodulin binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0004693	cyclin-dependent protein serine/threonine kinase activity
0.35	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity
0.35	GO:0005509	calcium ion binding
0.34	GO:0030332	cyclin binding
0.33	GO:0009931	calcium-dependent protein serine/threonine kinase activity

0.73	GO:0005964	phosphorylase kinase complex
0.37	GO:0005634	nucleus
0.35	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.32	GO:0031431	Dbf4-dependent protein kinase complex
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.73

EC:2.7.11.19

GO:0004689

tr|T1G4Y1|T1G4Y1_HELRO
Uncharacterized protein
Search

ANPRB

0.85	Atrial natriuretic peptide receptor

0.76	GO:0009190	cyclic nucleotide biosynthetic process
0.73	GO:0046068	cGMP metabolic process
0.63	GO:0035556	intracellular signal transduction
0.60	GO:0009152	purine ribonucleotide biosynthetic process
0.49	GO:0006468	protein phosphorylation
0.44	GO:0045332	phospholipid translocation
0.36	GO:0061067	negative regulation of dauer larval development
0.36	GO:0090325	regulation of locomotion involved in locomotory behavior
0.36	GO:0007168	receptor guanylyl cyclase signaling pathway
0.36	GO:0040015	negative regulation of multicellular organism growth

0.75	GO:0016849	phosphorus-oxygen lyase activity
0.69	GO:0009975	cyclase activity
0.51	GO:1901265	nucleoside phosphate binding
0.49	GO:0036094	small molecule binding
0.49	GO:0004672	protein kinase activity
0.45	GO:0097367	carbohydrate derivative binding
0.45	GO:0008144	drug binding
0.44	GO:0004012	phospholipid-translocating ATPase activity
0.44	GO:0043168	anion binding
0.40	GO:0000287	magnesium ion binding

0.45	GO:0005622	intracellular
0.36	GO:0043234	protein complex
0.36	GO:0043204	perikaryon
0.35	GO:0097730	non-motile cilium
0.35	GO:0030425	dendrite
0.35	GO:0005886	plasma membrane
0.34	GO:0043235	receptor complex
0.30	GO:0016021	integral component of membrane

0.75

GO:0016849

tr|T1G4Y2|T1G4Y2_HELRO
Uncharacterized protein
Search

0.54	Transcription elongation regulator 1

0.64	GO:0000122	negative regulation of transcription by RNA polymerase II
0.49	GO:0000398	mRNA splicing, via spliceosome
0.41	GO:0030522	intracellular receptor signaling pathway
0.41	GO:0043401	steroid hormone mediated signaling pathway
0.39	GO:0006457	protein folding
0.36	GO:0006351	transcription, DNA-templated

0.72	GO:0070064	proline-rich region binding
0.71	GO:0001103	RNA polymerase II repressing transcription factor binding
0.70	GO:0001106	RNA polymerase II transcription corepressor activity
0.61	GO:0042802	identical protein binding
0.42	GO:0004879	nuclear receptor activity
0.41	GO:0003707	steroid hormone receptor activity
0.39	GO:0051082	unfolded protein binding
0.38	GO:0043565	sequence-specific DNA binding
0.38	GO:0008270	zinc ion binding
0.36	GO:0032559	adenyl ribonucleotide binding

0.60	GO:0044428	nuclear part
0.56	GO:0031974	membrane-enclosed lumen
0.43	GO:1902494	catalytic complex
0.43	GO:0030529	intracellular ribonucleoprotein complex
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|T1G4Y3|T1G4Y3_HELRO
Uncharacterized protein
Search

RAB35

0.59	Putative rab subfamily protein of small gtpase

0.50	GO:0032456	endocytic recycling
0.47	GO:0048227	plasma membrane to endosome transport
0.46	GO:0036010	protein localization to endosome
0.45	GO:0000281	mitotic cytokinesis
0.43	GO:0031175	neuron projection development
0.43	GO:0019882	antigen processing and presentation
0.39	GO:1990090	cellular response to nerve growth factor stimulus
0.35	GO:0015031	protein transport
0.35	GO:1990182	exosomal secretion

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.41	GO:0071532	ankyrin repeat binding
0.41	GO:0032794	GTPase activating protein binding
0.35	GO:0004767	sphingomyelin phosphodiesterase activity

0.48	GO:0010008	endosome membrane
0.45	GO:0045171	intercellular bridge
0.45	GO:0045334	clathrin-coated endocytic vesicle
0.44	GO:0031253	cell projection membrane
0.44	GO:0005905	clathrin-coated pit
0.40	GO:0055037	recycling endosome
0.40	GO:0098993	anchored component of synaptic vesicle membrane
0.39	GO:0005769	early endosome
0.39	GO:0005739	mitochondrion
0.37	GO:0042470	melanosome

0.35	EC:3.1.4.12	GO:0004767
0.35	KEGG:R02541	GO:0004767

tr|T1G4Y4|T1G4Y4_HELRO
Uncharacterized protein
Search

0.38	GO:1903506	regulation of nucleic acid-templated transcription
0.38	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.38	GO:0010468	regulation of gene expression
0.36	GO:0032501	multicellular organismal process
0.35	GO:1902680	positive regulation of RNA biosynthetic process
0.35	GO:0071514	genetic imprinting
0.35	GO:0009653	anatomical structure morphogenesis
0.35	GO:0051569	regulation of histone H3-K4 methylation
0.35	GO:0006351	transcription, DNA-templated
0.34	GO:0016571	histone methylation

0.51	GO:0003676	nucleic acid binding
0.41	GO:0046872	metal ion binding
0.37	GO:0003700	DNA binding transcription factor activity
0.35	GO:0042393	histone binding

0.40	GO:0005634	nucleus
0.34	GO:0000785	chromatin
0.33	GO:0043233	organelle lumen
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|T1G4Y5|T1G4Y5_HELRO
Uncharacterized protein
Search

0.65	Rap guanine nucleotide exchange factor 2 (Fragment)

0.68	GO:0042127	regulation of cell proliferation
0.67	GO:0043547	positive regulation of GTPase activity
0.66	GO:0007264	small GTPase mediated signal transduction
0.41	GO:2000670	positive regulation of dendritic cell apoptotic process
0.41	GO:2000481	positive regulation of cAMP-dependent protein kinase activity
0.41	GO:0071321	cellular response to cGMP
0.41	GO:0090557	establishment of endothelial intestinal barrier
0.41	GO:0006289	nucleotide-excision repair
0.41	GO:0030033	microvillus assembly
0.41	GO:0050774	negative regulation of dendrite morphogenesis

0.79	GO:0017034	Rap guanyl-nucleotide exchange factor activity
0.68	GO:0005096	GTPase activator activity
0.41	GO:0031697	beta-1 adrenergic receptor binding
0.41	GO:0004003	ATP-dependent DNA helicase activity
0.40	GO:0070300	phosphatidic acid binding
0.40	GO:0050699	WW domain binding
0.40	GO:0030165	PDZ domain binding
0.40	GO:0030552	cAMP binding
0.34	GO:0030553	cGMP binding
0.34	GO:0019901	protein kinase binding

0.43	GO:0000439	core TFIIH complex
0.39	GO:0016324	apical plasma membrane
0.39	GO:0030139	endocytic vesicle
0.39	GO:0005923	bicellular tight junction
0.39	GO:0005770	late endosome
0.39	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0060102	collagen and cuticulin-based cuticle extracellular matrix
0.37	GO:0005829	cytosol
0.34	GO:0043025	neuronal cell body
0.34	GO:0043005	neuron projection

tr|T1G4Y6|T1G4Y6_HELRO
Uncharacterized protein
Search

0.65	GO:0007166	cell surface receptor signaling pathway
0.65	GO:0007186	G-protein coupled receptor signaling pathway
0.48	GO:0098869	cellular oxidant detoxification
0.42	GO:0001822	kidney development
0.40	GO:0055114	oxidation-reduction process
0.38	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.38	GO:0016525	negative regulation of angiogenesis
0.37	GO:0009952	anterior/posterior pattern specification
0.37	GO:0009792	embryo development ending in birth or egg hatching
0.37	GO:0097264	self proteolysis

0.66	GO:0004930	G-protein coupled receptor activity
0.59	GO:0030246	carbohydrate binding
0.51	GO:0004096	catalase activity
0.49	GO:0005509	calcium ion binding
0.45	GO:0020037	heme binding
0.37	GO:0042803	protein homodimerization activity
0.35	GO:0005262	calcium channel activity
0.35	GO:0004175	endopeptidase activity

0.35

GO:0005887

integral component of plasma membrane

0.51

EC:1.11.1.6

GO:0004096

tr|T1G4Y7|T1G4Y7_HELRO
Uncharacterized protein
Search

FURIN

0.71	Proprotein convertase subtilisin/kexin type

0.61	GO:0006508	proteolysis
0.47	GO:0042445	hormone metabolic process
0.46	GO:0032902	nerve growth factor production
0.45	GO:0051604	protein maturation
0.44	GO:0007368	determination of left/right symmetry
0.44	GO:0007354	zygotic determination of anterior/posterior axis, embryo
0.41	GO:0009100	glycoprotein metabolic process
0.41	GO:0006518	peptide metabolic process
0.40	GO:0032940	secretion by cell
0.38	GO:0048513	animal organ development

0.69	GO:0004252	serine-type endopeptidase activity
0.46	GO:0048406	nerve growth factor binding
0.43	GO:0008201	heparin binding
0.41	GO:0042802	identical protein binding
0.34	GO:0043559	insulin binding
0.33	GO:0051087	chaperone binding
0.33	GO:0032403	protein complex binding
0.33	GO:0004725	protein tyrosine phosphatase activity
0.33	GO:0005102	receptor binding
0.32	GO:0016301	kinase activity

0.46	GO:0005615	extracellular space
0.42	GO:0009986	cell surface
0.41	GO:0031012	extracellular matrix
0.37	GO:0034774	secretory granule lumen
0.36	GO:0030133	transport vesicle
0.35	GO:0043025	neuronal cell body
0.34	GO:0005783	endoplasmic reticulum
0.34	GO:0043679	axon terminus
0.34	GO:0030425	dendrite
0.33	GO:0005802	trans-Golgi network

0.69

GO:0004252

tr|T1G4Y8|T1G4Y8_HELRO
Uncharacterized protein
Search

0.11	High mobility group 1 protein (Fragment)

0.51	GO:0006260	DNA replication
0.51	GO:0006281	DNA repair
0.47	GO:0006351	transcription, DNA-templated
0.46	GO:1903506	regulation of nucleic acid-templated transcription
0.46	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.46	GO:0010468	regulation of gene expression
0.41	GO:0090139	mitochondrial DNA packaging
0.39	GO:0000001	mitochondrion inheritance
0.39	GO:0000002	mitochondrial genome maintenance
0.36	GO:0043043	peptide biosynthetic process

0.55	GO:0003677	DNA binding
0.37	GO:0003735	structural constituent of ribosome

0.61	GO:0005634	nucleus
0.53	GO:0005694	chromosome
0.40	GO:0031974	membrane-enclosed lumen
0.39	GO:0044446	intracellular organelle part
0.37	GO:0009295	nucleoid
0.36	GO:0044444	cytoplasmic part
0.36	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0031224	intrinsic component of membrane

tr|T1G4Y9|T1G4Y9_HELRO
Kinesin-like protein
Search

0.50	Kinesin-domain-containing protein

0.74	GO:0007018	microtubule-based movement
0.40	GO:0046907	intracellular transport
0.38	GO:0034613	cellular protein localization
0.38	GO:0000742	karyogamy involved in conjugation with cellular fusion
0.37	GO:1990942	mitotic metaphase chromosome recapture
0.37	GO:0015031	protein transport
0.37	GO:0051647	nucleus localization
0.37	GO:0000022	mitotic spindle elongation
0.37	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity
0.36	GO:0031122	cytoplasmic microtubule organization

0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0016887	ATPase activity
0.36	GO:0035091	phosphatidylinositol binding
0.35	GO:0005509	calcium ion binding
0.34	GO:0004826	phenylalanine-tRNA ligase activity
0.33	GO:0000287	magnesium ion binding

0.64	GO:0005874	microtubule
0.44	GO:0005871	kinesin complex
0.37	GO:0030981	cortical microtubule cytoskeleton
0.37	GO:0005818	aster
0.36	GO:0000778	condensed nuclear chromosome kinetochore
0.34	GO:0012505	endomembrane system
0.34	GO:0099023	tethering complex
0.34	GO:0031410	cytoplasmic vesicle
0.33	GO:0005816	spindle pole body
0.30	GO:0016021	integral component of membrane

0.42

GO:0016887

tr|T1G4Z0|T1G4Z0_HELRO
Uncharacterized protein
Search

tr|T1G4Z1|T1G4Z1_HELRO
Uncharacterized protein
Search

0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0010468	regulation of gene expression

0.57	GO:0005634	nucleus
0.30	GO:0044425	membrane part

tr|T1G4Z2|T1G4Z2_HELRO
Uncharacterized protein
Search

MTCH2

0.48	Mitochondrial carrier like protein 2

0.47	GO:0070585	protein localization to mitochondrion
0.44	GO:0043065	positive regulation of apoptotic process
0.41	GO:0010917	negative regulation of mitochondrial membrane potential
0.41	GO:0035701	hematopoietic stem cell migration
0.41	GO:0061484	hematopoietic stem cell homeostasis
0.41	GO:0097284	hepatocyte apoptotic process
0.41	GO:0045820	negative regulation of glycolytic process
0.41	GO:1902108	regulation of mitochondrial membrane permeability involved in apoptotic process
0.40	GO:1902229	regulation of intrinsic apoptotic signaling pathway in response to DNA damage
0.40	GO:2001022	positive regulation of response to DNA damage stimulus

0.34	GO:0008514	organic anion transmembrane transporter activity
0.34	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.33	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.39	GO:0005739	mitochondrion
0.39	GO:0031968	organelle outer membrane
0.38	GO:0070062	extracellular exosome
0.36	GO:0019866	organelle inner membrane
0.35	GO:0005634	nucleus
0.34	GO:0005887	integral component of plasma membrane

tr|T1G4Z3|T1G4Z3_HELRO
Uncharacterized protein
Search

DHRS1

0.30	Short-chain dehydrogenase

0.53	GO:0097502	mannosylation
0.51	GO:0043413	macromolecule glycosylation
0.51	GO:0009101	glycoprotein biosynthetic process
0.48	GO:0055114	oxidation-reduction process
0.45	GO:0006464	cellular protein modification process

0.57	GO:0000033	alpha-1,3-mannosyltransferase activity
0.49	GO:0016491	oxidoreductase activity
0.34	GO:0004312	fatty acid synthase activity

0.35	GO:0005783	endoplasmic reticulum
0.30	GO:0031224	intrinsic component of membrane

0.57

GO:0000033

tr|T1G4Z4|T1G4Z4_HELRO
Uncharacterized protein
Search

0.42

GO:0005515

protein binding

0.30

GO:0044425

membrane part

tr|T1G4Z5|T1G4Z5_HELRO
Uncharacterized protein
Search

tr|T1G4Z6|T1G4Z6_HELRO
Uncharacterized protein
Search

0.64	52 kDa repressor of the inhibitor of the protein kinase (Fragment)

0.57

GO:0016310

phosphorylation

0.68	GO:0046983	protein dimerization activity
0.60	GO:0016301	kinase activity

tr|T1G4Z7|T1G4Z7_HELRO
Uncharacterized protein
Search

0.44	GO:0043966	histone H3 acetylation
0.43	GO:0033563	dorsal/ventral axon guidance
0.39	GO:0051726	regulation of cell cycle
0.35	GO:0009952	anterior/posterior pattern specification
0.34	GO:0035902	response to immobilization stress
0.34	GO:0051602	response to electrical stimulus

0.54	GO:0046872	metal ion binding
0.43	GO:0043994	histone acetyltransferase activity (H3-K23 specific)
0.43	GO:0003676	nucleic acid binding
0.39	GO:0042393	histone binding

0.44	GO:0070776	MOZ/MORF histone acetyltransferase complex
0.38	GO:0016607	nuclear speck
0.34	GO:0000790	nuclear chromatin
0.34	GO:0043204	perikaryon
0.34	GO:0030425	dendrite
0.30	GO:0031224	intrinsic component of membrane

tr|T1G4Z8|T1G4Z8_HELRO
Uncharacterized protein
Search

tr|T1G4Z9|T1G4Z9_HELRO
Uncharacterized protein
Search

PIM3

0.53	Proto-oncogene serine/threonine-protein kinase pim-1

0.74	GO:0043066	negative regulation of apoptotic process
0.63	GO:0006468	protein phosphorylation
0.46	GO:0007346	regulation of mitotic cell cycle
0.43	GO:0007634	optokinetic behavior
0.42	GO:0048593	camera-type eye morphogenesis
0.40	GO:0042127	regulation of cell proliferation
0.39	GO:0008637	apoptotic mitochondrial changes
0.39	GO:0016239	positive regulation of macroautophagy
0.39	GO:0032091	negative regulation of protein binding
0.39	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus

0.68	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0043024	ribosomal small subunit binding
0.36	GO:0005515	protein binding
0.36	GO:0030145	manganese ion binding
0.35	GO:0005249	voltage-gated potassium channel activity
0.34	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity

0.40	GO:0005829	cytosol
0.36	GO:0005730	nucleolus
0.35	GO:0008076	voltage-gated potassium channel complex

0.68

GO:0004674

tr|T1G500|T1G500_HELRO
Secretory carrier-associated membrane protein
Search

SCAMP3

0.67	Secretory carrier-associated membrane protein 3

0.65	GO:0015031	protein transport
0.41	GO:0007616	long-term memory
0.41	GO:0007274	neuromuscular synaptic transmission
0.38	GO:0032526	response to retinoic acid
0.36	GO:0006468	protein phosphorylation
0.36	GO:0045721	negative regulation of gluconeogenesis
0.36	GO:0006836	neurotransmitter transport
0.35	GO:0010212	response to ionizing radiation
0.35	GO:0043484	regulation of RNA splicing
0.35	GO:0017156	calcium ion regulated exocytosis

0.47	GO:0031625	ubiquitin protein ligase binding
0.36	GO:0004672	protein kinase activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0042802	identical protein binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0019905	syntaxin binding

0.41	GO:0043195	terminal bouton
0.40	GO:0043227	membrane-bounded organelle
0.38	GO:0043229	intracellular organelle
0.37	GO:0043230	extracellular organelle
0.37	GO:0012505	endomembrane system
0.36	GO:0005615	extracellular space
0.35	GO:0044444	cytoplasmic part
0.34	GO:0044422	organelle part
0.33	GO:0098805	whole membrane
0.30	GO:0016021	integral component of membrane

tr|T1G501|T1G501_HELRO
Uncharacterized protein
Search

0.68

GO:0046983

protein dimerization activity

0.30

GO:0044425

membrane part

tr|T1G502|T1G502_HELRO
Uncharacterized protein
Search

tr|T1G503|T1G503_HELRO
Uncharacterized protein
Search

0.47	GO:0006369	termination of RNA polymerase II transcription
0.45	GO:0006367	transcription initiation from RNA polymerase II promoter
0.39	GO:0006357	regulation of transcription by RNA polymerase II
0.38	GO:0040034	regulation of development, heterochronic
0.37	GO:0045893	positive regulation of transcription, DNA-templated
0.36	GO:0009607	response to biotic stimulus
0.35	GO:0007018	microtubule-based movement
0.33	GO:0006281	DNA repair

0.51	GO:0003676	nucleic acid binding
0.39	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.38	GO:0046872	metal ion binding
0.37	GO:0003682	chromatin binding
0.35	GO:0005515	protein binding
0.35	GO:0003777	microtubule motor activity
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0032550	purine ribonucleoside binding

0.39	GO:0005634	nucleus
0.35	GO:0005874	microtubule
0.33	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1G504|T1G504_HELRO
Uncharacterized protein
Search

0.35	RNA binding protein Gbfne

0.44	GO:0036093	germ cell proliferation
0.43	GO:0060856	establishment of blood-brain barrier
0.42	GO:0048477	oogenesis
0.41	GO:0008049	male courtship behavior
0.39	GO:0050684	regulation of mRNA processing
0.35	GO:0048646	anatomical structure formation involved in morphogenesis
0.33	GO:0043484	regulation of RNA splicing
0.33	GO:0035150	regulation of tube size
0.33	GO:0002064	epithelial cell development
0.33	GO:0045664	regulation of neuron differentiation

0.59	GO:0003723	RNA binding
0.32	GO:0016491	oxidoreductase activity

0.34	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm
0.32	GO:0031974	membrane-enclosed lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.32

GO:0016491

tr|T1G505|T1G505_HELRO
Uncharacterized protein
Search

0.50	GO:0035066	positive regulation of histone acetylation
0.49	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle
0.47	GO:0008285	negative regulation of cell proliferation
0.46	GO:0045893	positive regulation of transcription, DNA-templated
0.44	GO:0045892	negative regulation of transcription, DNA-templated
0.44	GO:0043966	histone H3 acetylation
0.44	GO:0006357	regulation of transcription by RNA polymerase II
0.37	GO:0035902	response to immobilization stress
0.37	GO:0051602	response to electrical stimulus
0.36	GO:0016055	Wnt signaling pathway

0.51	GO:0042393	histone binding
0.50	GO:0140033	acetylation-dependent protein binding
0.49	GO:0002039	p53 binding
0.48	GO:0003714	transcription corepressor activity
0.47	GO:0046872	metal ion binding
0.47	GO:0003713	transcription coactivator activity
0.46	GO:0044212	transcription regulatory region DNA binding
0.45	GO:0008134	transcription factor binding
0.37	GO:0043994	histone acetyltransferase activity (H3-K23 specific)
0.34	GO:0030554	adenyl nucleotide binding

0.47	GO:0005654	nucleoplasm
0.44	GO:0005829	cytosol
0.42	GO:0031248	protein acetyltransferase complex
0.37	GO:0043204	perikaryon
0.36	GO:0030425	dendrite
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1G506|T1G506_HELRO
Uncharacterized protein
Search

FAM20B

0.97	glycosaminoglycan xylosylkinase

0.56	GO:1903955	positive regulation of protein targeting to mitochondrion
0.51	GO:0016310	phosphorylation
0.37	GO:0048701	embryonic cranial skeleton morphogenesis
0.37	GO:0030166	proteoglycan biosynthetic process

0.54	GO:0016772	transferase activity, transferring phosphorus-containing groups
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.50	GO:0005615	extracellular space
0.50	GO:0005794	Golgi apparatus
0.49	GO:0005654	nucleoplasm
0.36	GO:0098588	bounding membrane of organelle
0.36	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.54

EC:2.7

GO:0016772

tr|T1G507|T1G507_HELRO
Uncharacterized protein
Search

0.73	Transcriptional activator protein Pur-alpha

0.68	GO:0031935	regulation of chromatin silencing
0.38	GO:0009996	negative regulation of cell fate specification
0.38	GO:0071168	protein localization to chromatin
0.38	GO:0001708	cell fate specification
0.37	GO:0016573	histone acetylation
0.36	GO:0045892	negative regulation of transcription, DNA-templated
0.35	GO:0043043	peptide biosynthetic process
0.34	GO:0010467	gene expression
0.34	GO:0009059	macromolecule biosynthetic process

0.61	GO:0003729	mRNA binding
0.54	GO:0043565	sequence-specific DNA binding
0.38	GO:0042802	identical protein binding
0.38	GO:0004019	adenylosuccinate synthase activity
0.37	GO:0004402	histone acetyltransferase activity
0.35	GO:0003735	structural constituent of ribosome

0.72	GO:1990124	messenger ribonucleoprotein complex
0.52	GO:0005634	nucleus
0.43	GO:0005737	cytoplasm
0.37	GO:0031248	protein acetyltransferase complex
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0043232	intracellular non-membrane-bounded organelle
0.34	GO:0043234	protein complex
0.34	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.38	EC:6.3.4.4	GO:0004019
0.38	KEGG:R01135	GO:0004019

tr|T1G508|T1G508_HELRO
Uncharacterized protein
Search

0.92	RNA binding protein Luc7 2 like

0.84

GO:0006376

mRNA splice site selection

0.76	GO:0003729	mRNA binding
0.33	GO:0005509	calcium ion binding

0.82	GO:0005685	U1 snRNP
0.38	GO:0071004	U2-type prespliceosome
0.34	GO:0071011	precatalytic spliceosome
0.30	GO:0031224	intrinsic component of membrane

tr|T1G509|T1G509_HELRO
Uncharacterized protein
Search

0.78	GO:0035023	regulation of Rho protein signal transduction
0.66	GO:0065009	regulation of molecular function
0.56	GO:0035556	intracellular signal transduction
0.40	GO:0006468	protein phosphorylation
0.36	GO:0010717	regulation of epithelial to mesenchymal transition
0.35	GO:0007160	cell-matrix adhesion
0.35	GO:0030335	positive regulation of cell migration
0.35	GO:0008284	positive regulation of cell proliferation
0.35	GO:0016477	cell migration
0.34	GO:0050770	regulation of axonogenesis

0.78	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.56	GO:0005057	signal transducer activity, downstream of receptor
0.42	GO:0004674	protein serine/threonine kinase activity
0.37	GO:0048365	Rac GTPase binding
0.36	GO:0030554	adenyl nucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0032555	purine ribonucleotide binding
0.35	GO:0019900	kinase binding
0.35	GO:0008234	cysteine-type peptidase activity

0.42	GO:0005622	intracellular
0.36	GO:0044291	cell-cell contact zone
0.35	GO:0019897	extrinsic component of plasma membrane
0.35	GO:0009898	cytoplasmic side of plasma membrane
0.34	GO:0045202	synapse
0.33	GO:0044295	axonal growth cone
0.33	GO:0032587	ruffle membrane
0.33	GO:0044304	main axon
0.33	GO:0044309	neuron spine
0.32	GO:0043025	neuronal cell body

0.42

GO:0004674

tr|T1G510|T1G510_HELRO
Uncharacterized protein
Search

0.10	Laminin subunit alpha-5

0.77	GO:0045995	regulation of embryonic development
0.73	GO:0030334	regulation of cell migration
0.71	GO:0030155	regulation of cell adhesion
0.69	GO:0007155	cell adhesion
0.51	GO:0060541	respiratory system development
0.50	GO:0000904	cell morphogenesis involved in differentiation
0.49	GO:0009888	tissue development
0.49	GO:0120036	plasma membrane bounded cell projection organization
0.48	GO:0035011	melanotic encapsulation of foreign target
0.48	GO:0048513	animal organ development

0.68	GO:0005102	receptor binding
0.44	GO:0050839	cell adhesion molecule binding
0.43	GO:0032403	protein complex binding
0.35	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.32	GO:0003735	structural constituent of ribosome

0.54	GO:0005605	basal lamina
0.49	GO:0036062	presynaptic periactive zone
0.46	GO:0043083	synaptic cleft
0.42	GO:0005615	extracellular space
0.39	GO:0043234	protein complex
0.36	GO:0012505	endomembrane system
0.35	GO:0031982	vesicle
0.35	GO:0030424	axon
0.34	GO:0043230	extracellular organelle
0.34	GO:0030054	cell junction

0.35

GO:0004714

tr|T1G511|T1G511_HELRO
Uncharacterized protein
Search

0.38	Zinc finger protein (Fragment)

0.37	GO:0006357	regulation of transcription by RNA polymerase II
0.34	GO:0006351	transcription, DNA-templated
0.34	GO:0070868	heterochromatin organization involved in chromatin silencing
0.34	GO:0031935	regulation of chromatin silencing
0.34	GO:0007476	imaginal disc-derived wing morphogenesis
0.34	GO:0030178	negative regulation of Wnt signaling pathway
0.34	GO:0045931	positive regulation of mitotic cell cycle
0.33	GO:0007155	cell adhesion

0.51	GO:0003676	nucleic acid binding
0.37	GO:0046872	metal ion binding
0.37	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding

0.37	GO:0005634	nucleus
0.34	GO:0000792	heterochromatin
0.32	GO:0005739	mitochondrion

tr|T1G512|T1G512_HELRO
Uncharacterized protein
Search

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.49	GO:0008544	epidermis development
0.48	GO:0060429	epithelium development
0.48	GO:0048513	animal organ development
0.47	GO:0060901	regulation of hair cycle by canonical Wnt signaling pathway
0.47	GO:1902910	positive regulation of melanosome transport
0.47	GO:0051796	negative regulation of timing of catagen
0.47	GO:0032773	positive regulation of monophenol monooxygenase activity
0.47	GO:0032912	negative regulation of transforming growth factor beta2 production
0.46	GO:0048023	positive regulation of melanin biosynthetic process

0.70	GO:0005509	calcium ion binding
0.43	GO:0050839	cell adhesion molecule binding
0.39	GO:0004930	G-protein coupled receptor activity
0.35	GO:0032403	protein complex binding

0.56	GO:0005886	plasma membrane
0.42	GO:0005912	adherens junction
0.41	GO:0005911	cell-cell junction
0.36	GO:0031254	cell trailing edge
0.36	GO:0045178	basal part of cell
0.36	GO:0098858	actin-based cell projection
0.35	GO:0030055	cell-substrate junction
0.35	GO:0005654	nucleoplasm
0.34	GO:0045177	apical part of cell
0.30	GO:0016021	integral component of membrane

tr|T1G513|T1G513_HELRO
Uncharacterized protein
Search

GALK1

0.48	Epididymis secretory protein Li 19

0.76	GO:0006012	galactose metabolic process
0.74	GO:0046835	carbohydrate phosphorylation
0.53	GO:0061622	glycolytic process through glucose-1-phosphate
0.49	GO:0019402	galactitol metabolic process
0.47	GO:0019320	hexose catabolic process
0.34	GO:0051260	protein homooligomerization

0.81	GO:0004335	galactokinase activity
0.78	GO:0005534	galactose binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0000287	magnesium ion binding
0.33	GO:0005515	protein binding

0.48	GO:0005737	cytoplasm
0.35	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.81	EC:2.7.1.6	GO:0004335
0.81	KEGG:R01092	GO:0004335

tr|T1G514|T1G514_HELRO
FACT complex subunit SSRP1
Search

SSRP1

0.75	FACT complex subunit SSRP1

0.66	GO:0006260	DNA replication
0.64	GO:0006281	DNA repair
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.36	GO:0051726	regulation of cell cycle
0.34	GO:1901796	regulation of signal transduction by p53 class mediator
0.32	GO:0055114	oxidation-reduction process

0.55	GO:0003677	DNA binding
0.50	GO:0003682	chromatin binding
0.34	GO:0005515	protein binding
0.33	GO:0003723	RNA binding
0.32	GO:0016491	oxidoreductase activity

0.67	GO:0005694	chromosome
0.61	GO:0005634	nucleus
0.36	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016491

tr|T1G515|T1G515_HELRO
D-tyrosyl-tRNA(Tyr) deacylase
Search

0.55	D-aminoacyl-tRNA deacylase

0.73	GO:0106074	aminoacyl-tRNA metabolism involved in translational fidelity
0.50	GO:0006487	protein N-linked glycosylation
0.36	GO:1900831	D-leucine metabolic process
0.36	GO:1900828	D-tyrosine metabolic process
0.36	GO:0019478	D-amino acid catabolic process
0.36	GO:0006552	leucine catabolic process
0.35	GO:0006572	tyrosine catabolic process
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.83	GO:0051500	D-tyrosyl-tRNA(Tyr) deacylase activity
0.66	GO:0000049	tRNA binding
0.41	GO:0106026	Gly-tRNA(Ala) hydrolase activity
0.38	GO:0016740	transferase activity
0.36	GO:0097358	D-leucyl-tRNA(Leu) deacylase activity
0.33	GO:0043908	Ser(Gly)-tRNA(Ala) hydrolase activity

0.51	GO:0008250	oligosaccharyltransferase complex
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.38

GO:0016740

tr|T1G516|T1G516_HELRO
Uncharacterized protein
Search

tr|T1G517|T1G517_HELRO
Uncharacterized protein
Search

0.58	GO:0045995	regulation of embryonic development
0.56	GO:0030334	regulation of cell migration
0.55	GO:0048496	maintenance of animal organ identity
0.54	GO:0030155	regulation of cell adhesion
0.54	GO:0030182	neuron differentiation
0.54	GO:0009888	tissue development
0.53	GO:0045494	photoreceptor cell maintenance
0.52	GO:0007155	cell adhesion
0.51	GO:0048839	inner ear development
0.51	GO:0007605	sensory perception of sound

0.53	GO:0005102	receptor binding
0.52	GO:0017022	myosin binding
0.51	GO:0005518	collagen binding
0.51	GO:0005509	calcium ion binding
0.48	GO:0042803	protein homodimerization activity
0.37	GO:0008022	protein C-terminus binding
0.35	GO:0050839	cell adhesion molecule binding
0.33	GO:0008270	zinc ion binding

0.58	GO:0005604	basement membrane
0.56	GO:0060171	stereocilium membrane
0.55	GO:0002142	stereocilia ankle link complex
0.55	GO:1990696	USH2 complex
0.54	GO:1990075	periciliary membrane compartment
0.53	GO:0001917	photoreceptor inner segment
0.52	GO:0032391	photoreceptor connecting cilium
0.51	GO:0036064	ciliary basal body
0.50	GO:0016324	apical plasma membrane
0.50	GO:0036062	presynaptic periactive zone

tr|T1G518|T1G518_HELRO
Uncharacterized protein
Search

tr|T1G519|T1G519_HELRO
Uncharacterized protein
Search

RAB32

0.91	RAS oncogene family member RAB32

0.69	GO:0016192	vesicle-mediated transport
0.61	GO:0048753	pigment granule organization
0.57	GO:0035646	endosome to melanosome transport
0.55	GO:0090382	phagosome maturation
0.50	GO:0007005	mitochondrion organization
0.49	GO:0072657	protein localization to membrane
0.48	GO:0070925	organelle assembly
0.46	GO:0051452	intracellular pH reduction
0.45	GO:0019882	antigen processing and presentation
0.44	GO:0060036	notochord cell vacuolation

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.58	GO:0036461	BLOC-2 complex binding
0.58	GO:0035651	AP-3 adaptor complex binding
0.56	GO:0035650	AP-1 adaptor complex binding
0.56	GO:0030742	GTP-dependent protein binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0035612	AP-2 adaptor complex binding

0.80	GO:0005802	trans-Golgi network
0.72	GO:0031982	vesicle
0.53	GO:0044233	ER-mitochondrion membrane contact site
0.48	GO:0098805	whole membrane
0.48	GO:0098588	bounding membrane of organelle
0.47	GO:0005764	lysosome
0.45	GO:0005739	mitochondrion
0.45	GO:0005783	endoplasmic reticulum
0.42	GO:0019867	outer membrane
0.42	GO:0005776	autophagosome

0.34	EC:3.1.4.12	GO:0004767
0.34	KEGG:R02541	GO:0004767

tr|T1G520|T1G520_HELRO
Uncharacterized protein
Search

0.78	Translocase of inner mitochondrial membrane 8 protein b

0.65	GO:0015031	protein transport
0.45	GO:0090151	establishment of protein localization to mitochondrial membrane
0.45	GO:0007007	inner mitochondrial membrane organization
0.44	GO:1990542	mitochondrial transmembrane transport
0.42	GO:0046907	intracellular transport
0.38	GO:0030001	metal ion transport
0.37	GO:0098655	cation transmembrane transport

0.53	GO:0046872	metal ion binding
0.43	GO:0008565	protein transporter activity
0.39	GO:0046873	metal ion transmembrane transporter activity
0.35	GO:1904680	peptide transmembrane transporter activity
0.35	GO:0022884	macromolecule transmembrane transporter activity
0.35	GO:0033220	amide-transporting ATPase activity

0.60	GO:0005739	mitochondrion
0.44	GO:0031970	organelle envelope lumen
0.41	GO:1990351	transporter complex
0.36	GO:0019866	organelle inner membrane
0.33	GO:0098796	membrane protein complex
0.33	GO:0005829	cytosol
0.33	GO:0005576	extracellular region

tr|T1G521|T1G521_HELRO
Uncharacterized protein
Search

tr|T1G522|T1G522_HELRO
Uncharacterized protein
Search

ARL5B

0.75	ADP-ribosylation factorB

0.51	GO:1903292	protein localization to Golgi membrane
0.44	GO:0042147	retrograde transport, endosome to Golgi
0.33	GO:0035999	tetrahydrofolate interconversion
0.33	GO:0006555	methionine metabolic process
0.32	GO:0055114	oxidation-reduction process

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0003924	GTPase activity
0.34	GO:0004489	methylenetetrahydrofolate reductase (NAD(P)H) activity

0.45	GO:0005622	intracellular
0.40	GO:0012505	endomembrane system
0.38	GO:0044422	organelle part
0.37	GO:0043227	membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

0.34	EC:1.5.1.20	GO:0004489
0.34	KEGG:R01224 KEGG:R07168	GO:0004489

tr|T1G524|T1G524_HELRO
Uncharacterized protein
Search

SPO11

0.91	Ribonucleic acid export 1

0.83	GO:0000737	DNA catabolic process, endonucleolytic
0.63	GO:0007131	reciprocal meiotic recombination
0.56	GO:0007141	male meiosis I
0.56	GO:0045141	meiotic telomere clustering
0.55	GO:0007130	synaptonemal complex assembly
0.55	GO:0001541	ovarian follicle development
0.54	GO:0034502	protein localization to chromosome
0.53	GO:0007286	spermatid development
0.53	GO:0048477	oogenesis
0.52	GO:0006302	double-strand break repair

0.55	GO:0003677	DNA binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0016889	endodeoxyribonuclease activity, producing 3'-phosphomonoesters
0.46	GO:0061505	DNA topoisomerase II activity
0.44	GO:0008094	DNA-dependent ATPase activity
0.34	GO:0005515	protein binding
0.34	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters
0.33	GO:0046872	metal ion binding

0.68	GO:0005694	chromosome
0.44	GO:0044446	intracellular organelle part
0.43	GO:0043233	organelle lumen
0.41	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.47

EC:3.1.22

GO:0016889

tr|T1G525|T1G525_HELRO
Guanylate cyclase
Search

0.44	Guanylate cyclase

0.80	GO:0006182	cGMP biosynthetic process
0.62	GO:0006468	protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.37	GO:0060038	cardiac muscle cell proliferation
0.36	GO:0018212	peptidyl-tyrosine modification
0.34	GO:0061067	negative regulation of dauer larval development
0.34	GO:0043052	thermotaxis
0.34	GO:0007168	receptor guanylyl cyclase signaling pathway
0.34	GO:0040040	thermosensory behavior
0.34	GO:0090325	regulation of locomotion involved in locomotory behavior

0.81	GO:0004383	guanylate cyclase activity
0.62	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0004016	adenylate cyclase activity
0.33	GO:0032550	purine ribonucleoside binding
0.32	GO:0019001	guanyl nucleotide binding
0.32	GO:0046872	metal ion binding

0.44	GO:0005622	intracellular
0.37	GO:0043234	protein complex
0.36	GO:0005886	plasma membrane
0.34	GO:0043005	neuron projection
0.34	GO:0005929	cilium
0.34	GO:0120038	plasma membrane bounded cell projection part
0.34	GO:0005902	microvillus
0.34	GO:0043204	perikaryon
0.30	GO:0016021	integral component of membrane

0.81

GO:0004383

tr|T1G526|T1G526_HELRO
Uncharacterized protein
Search

tr|T1G527|T1G527_HELRO
Uncharacterized protein
Search

0.88	Homeobox protein MOX-1

0.58	GO:0007275	multicellular organism development
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.49	GO:0060429	epithelium development
0.47	GO:1902680	positive regulation of RNA biosynthetic process
0.45	GO:0009653	anatomical structure morphogenesis
0.45	GO:0006366	transcription by RNA polymerase II
0.43	GO:0048857	neural nucleus development
0.42	GO:0060322	head development

0.64	GO:0043565	sequence-specific DNA binding
0.52	GO:0003700	DNA binding transcription factor activity
0.47	GO:0071837	HMG box domain binding
0.46	GO:0001047	core promoter binding
0.45	GO:0003682	chromatin binding
0.44	GO:0001012	RNA polymerase II regulatory region DNA binding
0.43	GO:0003690	double-stranded DNA binding
0.34	GO:0051721	protein phosphatase 2A binding

0.61	GO:0005634	nucleus
0.39	GO:0005829	cytosol
0.39	GO:0043233	organelle lumen
0.36	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

tr|T1G528|T1G528_HELRO
Uncharacterized protein
Search

tr|T1G529|T1G529_HELRO
Uncharacterized protein
Search

EXTL3

0.88	Exostosin like glycosyltransferase 3

0.74	GO:0006486	protein glycosylation
0.61	GO:0015012	heparan sulfate proteoglycan biosynthetic process
0.45	GO:0035118	embryonic pectoral fin morphogenesis
0.45	GO:0033564	anterior/posterior axon guidance
0.45	GO:0009967	positive regulation of signal transduction
0.44	GO:0040036	regulation of fibroblast growth factor receptor signaling pathway
0.44	GO:0031290	retinal ganglion cell axon guidance
0.44	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process
0.44	GO:0048538	thymus development
0.44	GO:0030210	heparin biosynthetic process

0.65	GO:0016757	transferase activity, transferring glycosyl groups
0.34	GO:0008240	tripeptidyl-peptidase activity
0.34	GO:0004872	receptor activity
0.34	GO:0046872	metal ion binding
0.33	GO:0004252	serine-type endopeptidase activity

0.50	GO:0005794	Golgi apparatus
0.50	GO:0005783	endoplasmic reticulum
0.36	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0031984	organelle subcompartment
0.33	GO:0098588	bounding membrane of organelle
0.30	GO:0031224	intrinsic component of membrane

0.65

GO:0016757

tr|T1G530|T1G530_HELRO
Uncharacterized protein
Search

0.41	Zinc finger MYM-type protein (Fragment)

0.39	GO:0006357	regulation of transcription by RNA polymerase II
0.35	GO:0007275	multicellular organism development
0.33	GO:0016310	phosphorylation

0.68	GO:0046983	protein dimerization activity
0.39	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.36	GO:0003677	DNA binding
0.33	GO:0016301	kinase activity

0.39	GO:0005654	nucleoplasm
0.34	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

tr|T1G531|T1G531_HELRO
Uncharacterized protein
Search

tr|T1G532|T1G532_HELRO
NADH-ubiquinone oxidoreductase chain 3
Search

ND3

0.44	NADH-ubiquinone oxidoreductase chain 3

0.53

GO:0055114

oxidation-reduction process

0.69	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.44	GO:0048038	quinone binding

0.60	GO:0070469	respiratory chain
0.59	GO:0031966	mitochondrial membrane
0.39	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0008137

tr|T1G533|T1G533_HELRO
Uncharacterized protein
Search

0.84	Transcription elongation factor B polypeptide

0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.60	GO:0006414	translational elongation
0.43	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter
0.41	GO:0016567	protein ubiquitination
0.40	GO:0007474	imaginal disc-derived wing vein specification
0.35	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia
0.34	GO:0043687	post-translational protein modification
0.34	GO:0006368	transcription elongation from RNA polymerase II promoter
0.33	GO:0016032	viral process

0.60	GO:0003746	translation elongation factor activity
0.41	GO:0004842	ubiquitin-protein transferase activity
0.34	GO:0005515	protein binding
0.33	GO:0044877	macromolecular complex binding
0.33	GO:0016874	ligase activity

0.47	GO:0070449	elongin complex
0.40	GO:0031462	Cul2-RING ubiquitin ligase complex
0.40	GO:0005705	polytene chromosome interband
0.35	GO:0030891	VCB complex
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.33	EC:6	GO:0016874
0.41	KEGG:R03876	GO:0004842

tr|T1G534|T1G534_HELRO
Uncharacterized protein
Search

PPIL4

0.80	Peptidylprolyl isomerase like 4

0.72	GO:0000413	protein peptidyl-prolyl isomerization
0.52	GO:1901407	regulation of phosphorylation of RNA polymerase II C-terminal domain
0.39	GO:1905473	positive regulation of histone H3-K79 dimethylation
0.38	GO:1905437	positive regulation of histone H3-K4 trimethylation
0.38	GO:2001255	positive regulation of histone H3-K36 trimethylation
0.38	GO:0040026	positive regulation of vulval development
0.38	GO:0060282	positive regulation of oocyte development
0.38	GO:2000543	positive regulation of gastrulation
0.37	GO:0050685	positive regulation of mRNA processing
0.37	GO:0033120	positive regulation of RNA splicing

0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.59	GO:0003723	RNA binding
0.37	GO:0000993	RNA polymerase II core binding
0.34	GO:0005319	lipid transporter activity

0.47	GO:0005654	nucleoplasm
0.46	GO:0005829	cytosol
0.37	GO:0035327	transcriptionally active chromatin
0.33	GO:0000790	nuclear chromatin
0.30	GO:0031224	intrinsic component of membrane

0.72

EC:5.2.1.8

GO:0003755

tr|T1G535|T1G535_HELRO
Uncharacterized protein
Search

RAB39B

0.83	Putative rab subfamily protein of small gtpase

0.47	GO:0010506	regulation of autophagy
0.46	GO:0050808	synapse organization
0.46	GO:0007030	Golgi organization
0.43	GO:0016192	vesicle-mediated transport
0.36	GO:0006914	autophagy
0.35	GO:0090383	phagosome acidification
0.35	GO:0015031	protein transport
0.34	GO:0007040	lysosome organization
0.34	GO:0090174	organelle membrane fusion
0.34	GO:0016050	vesicle organization

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032553	ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0031489	myosin V binding
0.34	GO:0004767	sphingomyelin phosphodiesterase activity
0.33	GO:0019901	protein kinase binding

0.53	GO:0005794	Golgi apparatus
0.48	GO:0043005	neuron projection
0.47	GO:0031982	vesicle
0.46	GO:0005801	cis-Golgi network
0.42	GO:0031984	organelle subcompartment
0.35	GO:0031090	organelle membrane
0.34	GO:0005886	plasma membrane

0.34	EC:3.1.4.12	GO:0004767
0.34	KEGG:R02541	GO:0004767

tr|T1G536|T1G536_HELRO
Uncharacterized protein
Search

tr|T1G538|T1G538_HELRO
Uncharacterized protein
Search

0.66	LIM domain kinase 1

0.62	GO:0006468	protein phosphorylation
0.56	GO:0032233	positive regulation of actin filament bundle assembly
0.56	GO:0051444	negative regulation of ubiquitin-protein transferase activity
0.55	GO:0051492	regulation of stress fiber assembly
0.54	GO:0045773	positive regulation of axon extension
0.44	GO:0030036	actin cytoskeleton organization
0.42	GO:0050482	arachidonic acid secretion
0.42	GO:0035556	intracellular signal transduction
0.39	GO:0006644	phospholipid metabolic process
0.37	GO:0001878	response to yeast

0.62	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0046872	metal ion binding
0.51	GO:0031072	heat shock protein binding
0.48	GO:0046982	protein heterodimerization activity
0.42	GO:0004623	phospholipase A2 activity
0.42	GO:0004871	signal transducer activity
0.34	GO:0005201	extracellular matrix structural constituent

0.52	GO:0016607	nuclear speck
0.52	GO:0030027	lamellipodium
0.51	GO:0043005	neuron projection
0.51	GO:0005925	focal adhesion
0.47	GO:0005829	cytosol
0.44	GO:0005794	Golgi apparatus
0.37	GO:0005576	extracellular region
0.36	GO:0030427	site of polarized growth
0.36	GO:0120038	plasma membrane bounded cell projection part
0.35	GO:0048471	perinuclear region of cytoplasm

0.42

EC:3.1.1.4

GO:0004623

tr|T1G539|T1G539_HELRO
Uncharacterized protein
Search

tr|T1G540|T1G540_HELRO
Uncharacterized protein
Search

CELF1

0.73	CUGBP Elav-like family member 1 (Fragment)

0.49	GO:0007281	germ cell development
0.48	GO:0051094	positive regulation of developmental process
0.47	GO:0040014	regulation of multicellular organism growth
0.47	GO:0006376	mRNA splice site selection
0.46	GO:0048515	spermatid differentiation
0.46	GO:0045927	positive regulation of growth
0.44	GO:0014881	regulation of myofibril size
0.44	GO:0051240	positive regulation of multicellular organismal process
0.44	GO:0007319	negative regulation of oskar mRNA translation
0.43	GO:0036099	female germ-line stem cell population maintenance

0.59	GO:0003723	RNA binding
0.46	GO:0031369	translation initiation factor binding
0.34	GO:0000900	translation repressor activity, nucleic acid binding

0.45	GO:0005654	nucleoplasm
0.44	GO:0045495	pole plasm
0.41	GO:0031965	nuclear membrane
0.41	GO:0036464	cytoplasmic ribonucleoprotein granule
0.30	GO:0031224	intrinsic component of membrane

tr|T1G541|T1G541_HELRO
Uncharacterized protein
Search

tr|T1G542|T1G542_HELRO
Uncharacterized protein
Search

0.47	Sorting nexin-14

0.50	GO:0097352	autophagosome maturation
0.35	GO:0015031	protein transport

0.80

GO:0080025

phosphatidylinositol-3,5-bisphosphate binding

0.47	GO:0005770	late endosome
0.47	GO:0005764	lysosome
0.37	GO:0030425	dendrite
0.35	GO:0098852	lytic vacuole membrane
0.35	GO:0010008	endosome membrane
0.30	GO:0044425	membrane part

tr|T1G543|T1G543_HELRO
Uncharacterized protein
Search

WDR5

0.63	WD repeat-containing protein 5

0.76	GO:0051568	histone H3-K4 methylation
0.74	GO:0043982	histone H4-K8 acetylation
0.74	GO:0043981	histone H4-K5 acetylation
0.73	GO:0043984	histone H4-K16 acetylation
0.70	GO:0035948	positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter
0.69	GO:0043966	histone H3 acetylation
0.63	GO:0048731	system development
0.58	GO:0060271	cilium assembly
0.56	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.55	GO:0048737	imaginal disc-derived appendage development

0.75	GO:0043996	histone acetyltransferase activity (H4-K8 specific)
0.75	GO:0046972	histone acetyltransferase activity (H4-K16 specific)
0.75	GO:0043995	histone acetyltransferase activity (H4-K5 specific)
0.69	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.68	GO:0140034	methylation-dependent protein binding
0.65	GO:0042393	histone binding
0.36	GO:0003743	translation initiation factor activity
0.36	GO:0008137	NADH dehydrogenase (ubiquinone) activity

0.77	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex
0.77	GO:0044666	MLL3/4 complex
0.74	GO:0048188	Set1C/COMPASS complex
0.69	GO:0044665	MLL1/2 complex
0.60	GO:0036064	ciliary basal body
0.60	GO:0044545	NSL complex
0.39	GO:0019013	viral nucleocapsid
0.37	GO:0030529	intracellular ribonucleoprotein complex
0.35	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

0.36

GO:0008137

tr|T1G544|T1G544_HELRO
Uncharacterized protein
Search

SRP14

0.44	Signal recognition particle 14

0.76	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.46	GO:0042493	response to drug
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0006915	apoptotic process

0.85	GO:0030942	endoplasmic reticulum signal peptide binding
0.78	GO:0008312	7S RNA binding
0.36	GO:0050825	ice binding
0.33	GO:0005515	protein binding

0.82	GO:0005786	signal recognition particle, endoplasmic reticulum targeting
0.42	GO:0005634	nucleus
0.36	GO:0070062	extracellular exosome
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen
0.34	GO:0005829	cytosol

tr|T1G545|T1G545_HELRO
Uncharacterized protein
Search

0.50	Calcyphosine like

0.32	GO:0035556	intracellular signal transduction
0.32	GO:0016310	phosphorylation

0.70	GO:0005509	calcium ion binding
0.32	GO:0016301	kinase activity

0.34	GO:0070062	extracellular exosome
0.32	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

tr|T1G546|T1G546_HELRO
Uncharacterized protein
Search

0.51	ADP-ribosylation factor-like protein 2

0.51	GO:0021943	formation of radial glial scaffolds
0.50	GO:0021830	interneuron migration from the subpallium to the cortex
0.50	GO:0070986	left/right axis specification
0.49	GO:0021532	neural tube patterning
0.48	GO:0001947	heart looping
0.48	GO:1905515	non-motile cilium assembly
0.48	GO:0007224	smoothened signaling pathway
0.48	GO:0009953	dorsal/ventral pattern formation
0.38	GO:0010226	response to lithium ion
0.35	GO:0035845	photoreceptor cell outer segment organization

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0030742	GTP-dependent protein binding
0.33	GO:0008168	methyltransferase activity
0.32	GO:0003723	RNA binding
0.32	GO:0003735	structural constituent of ribosome
0.32	GO:0008270	zinc ion binding
0.32	GO:0016787	hydrolase activity

0.49	GO:0060170	ciliary membrane
0.47	GO:0005930	axoneme
0.46	GO:0031514	motile cilium
0.35	GO:0097544	ciliary shaft
0.34	GO:0097546	ciliary base
0.34	GO:0097731	9+0 non-motile cilium
0.32	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0008168

tr|T1G547|T1G547_HELRO
Uncharacterized protein
Search

0.66	GO:0030036	actin cytoskeleton organization
0.43	GO:0031268	pseudopodium organization
0.43	GO:0046847	filopodium assembly
0.42	GO:0051638	barbed-end actin filament uncapping
0.41	GO:0031589	cell-substrate adhesion
0.40	GO:0030838	positive regulation of actin filament polymerization
0.39	GO:0000902	cell morphogenesis
0.39	GO:0097435	supramolecular fiber organization
0.39	GO:0048870	cell motility

0.74	GO:0003779	actin binding
0.70	GO:0017048	Rho GTPase binding
0.43	GO:0005522	profilin binding
0.40	GO:0032403	protein complex binding

0.42	GO:0030175	filopodium
0.39	GO:0015629	actin cytoskeleton
0.37	GO:0005938	cell cortex
0.30	GO:0016020	membrane

tr|T1G548|T1G548_HELRO
Proteasome subunit beta type
Search

PSMB5

0.53	Proteasome subunit beta type

0.71	GO:0051603	proteolysis involved in cellular protein catabolic process
0.66	GO:0043632	modification-dependent macromolecule catabolic process
0.46	GO:0006979	response to oxidative stress
0.40	GO:0080129	proteasome core complex assembly
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.35	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation

0.76	GO:0070003	threonine-type peptidase activity
0.64	GO:0004175	endopeptidase activity
0.33	GO:0005515	protein binding

0.75	GO:0005839	proteasome core complex
0.60	GO:0005634	nucleus
0.49	GO:0005813	centrosome
0.48	GO:0005737	cytoplasm
0.44	GO:0031974	membrane-enclosed lumen
0.36	GO:0070062	extracellular exosome

tr|T1G549|T1G549_HELRO
Uncharacterized protein
Search

tr|T1G550|T1G550_HELRO
Uncharacterized protein
Search

0.22	Cytochrome c oxidase subunit VIc

0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0022900	electron transport chain

0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity

0.30

GO:0044425

membrane part

0.65

EC:1.9.3

GO:0016676

tr|T1G551|T1G551_HELRO
Uncharacterized protein
Search

0.61	Zinc finger MYM-type protein (Fragment)

0.40	GO:0006357	regulation of transcription by RNA polymerase II
0.35	GO:0007275	multicellular organism development
0.33	GO:0016310	phosphorylation

0.68	GO:0046983	protein dimerization activity
0.40	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.36	GO:0003677	DNA binding
0.33	GO:0016301	kinase activity

0.39	GO:0005654	nucleoplasm
0.35	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

tr|T1G552|T1G552_HELRO
Non-specific serine/threonine protein kinase
Search

MARK2

0.60	Non-specific serine/threonine protein kinase

0.80	GO:0030010	establishment of cell polarity
0.75	GO:0000226	microtubule cytoskeleton organization
0.62	GO:0006468	protein phosphorylation
0.49	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity
0.48	GO:0010976	positive regulation of neuron projection development
0.48	GO:0050770	regulation of axonogenesis
0.41	GO:0035556	intracellular signal transduction

0.69	GO:0004674	protein serine/threonine kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0045296	cadherin binding
0.42	GO:0000287	magnesium ion binding

0.51	GO:0097427	microtubule bundle
0.49	GO:0016328	lateral plasma membrane
0.48	GO:0005884	actin filament
0.44	GO:0005654	nucleoplasm

0.69

GO:0004674

tr|T1G553|T1G553_HELRO
Uncharacterized protein
Search

0.93	NVHD41-ANTP class homeobox protein (Fragment)

0.53	GO:1903506	regulation of nucleic acid-templated transcription
0.53	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.52	GO:0010468	regulation of gene expression
0.51	GO:0048536	spleen development
0.51	GO:0055123	digestive system development
0.51	GO:0009888	tissue development
0.49	GO:0030178	negative regulation of Wnt signaling pathway
0.49	GO:0009952	anterior/posterior pattern specification
0.49	GO:0006366	transcription by RNA polymerase II
0.48	GO:0030154	cell differentiation

0.59	GO:0043565	sequence-specific DNA binding
0.51	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.49	GO:0001012	RNA polymerase II regulatory region DNA binding
0.47	GO:0003690	double-stranded DNA binding
0.39	GO:0003682	chromatin binding
0.35	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.39	GO:0005667	transcription factor complex
0.38	GO:0005829	cytosol
0.37	GO:0043233	organelle lumen
0.36	GO:0044446	intracellular organelle part

tr|T1G554|T1G554_HELRO
Uncharacterized protein
Search

tr|T1G555|T1G555_HELRO
Uncharacterized protein
Search

0.40	Ribosomal RNA-processing protein 8 (inferred by orthology to a C. elegans protein)

0.63	GO:0032259	methylation
0.52	GO:0046015	regulation of transcription by glucose
0.52	GO:0000183	chromatin silencing at rDNA
0.51	GO:0042149	cellular response to glucose starvation
0.51	GO:0071158	positive regulation of cell cycle arrest
0.50	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator
0.38	GO:0006364	rRNA processing
0.37	GO:0043412	macromolecule modification
0.36	GO:0042273	ribosomal large subunit biogenesis
0.35	GO:0044260	cellular macromolecule metabolic process

0.63	GO:0008168	methyltransferase activity
0.51	GO:0140034	methylation-dependent protein binding
0.50	GO:0042393	histone binding
0.36	GO:0032550	purine ribonucleoside binding
0.36	GO:0032561	guanyl ribonucleotide binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0140102	catalytic activity, acting on a rRNA
0.35	GO:0004672	protein kinase activity
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0008144	drug binding

0.73	GO:0005730	nucleolus
0.53	GO:0005677	chromatin silencing complex
0.52	GO:0033553	rDNA heterochromatin
0.44	GO:0005829	cytosol
0.39	GO:0005886	plasma membrane
0.36	GO:0030686	90S preribosome
0.30	GO:0031224	intrinsic component of membrane

0.63

GO:0008168

tr|T1G556|T1G556_HELRO
Uncharacterized protein
Search

0.74	Potassium voltage-gated channel subfamily C member

0.73	GO:0071805	potassium ion transmembrane transport
0.73	GO:0034765	regulation of ion transmembrane transport
0.73	GO:0051260	protein homooligomerization
0.34	GO:0030431	sleep
0.34	GO:0006379	mRNA cleavage
0.32	GO:0006351	transcription, DNA-templated

0.78	GO:0005249	voltage-gated potassium channel activity
0.35	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.33	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.33	GO:0046872	metal ion binding
0.32	GO:0003676	nucleic acid binding

0.78

GO:0008076

voltage-gated potassium channel complex

0.35

GO:0004114

tr|T1G557|T1G557_HELRO
Uncharacterized protein
Search

0.81	Succinate dehydrogenase complex assembly factor 3

0.49	GO:0006105	succinate metabolic process
0.49	GO:0055093	response to hyperoxia
0.49	GO:0050881	musculoskeletal movement
0.46	GO:0006979	response to oxidative stress
0.44	GO:0097032	mitochondrial respiratory chain complex II biogenesis
0.44	GO:0034552	respiratory chain complex II assembly
0.43	GO:0006111	regulation of gluconeogenesis
0.42	GO:0033108	mitochondrial respiratory chain complex assembly
0.35	GO:0006468	protein phosphorylation
0.34	GO:0015976	carbon utilization

0.35	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.35	GO:0004672	protein kinase activity
0.34	GO:0005506	iron ion binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0016787	hydrolase activity

0.60	GO:0005739	mitochondrion
0.42	GO:0031970	organelle envelope lumen
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:1.13.11

GO:0016702

tr|T1G558|T1G558_HELRO
Uncharacterized protein
Search

0.36

GO:0055085

transmembrane transport

0.30

GO:0044425

membrane part

tr|T1G559|T1G559_HELRO
Uncharacterized protein
Search

DNAJC1

0.60	DnaJ heat shock protein family (Hsp40) member C1

0.50	GO:0050708	regulation of protein secretion
0.47	GO:0006417	regulation of translation
0.46	GO:0006457	protein folding
0.34	GO:0032781	positive regulation of ATPase activity
0.34	GO:0045861	negative regulation of proteolysis
0.33	GO:0006986	response to unfolded protein
0.33	GO:0030433	ubiquitin-dependent ERAD pathway

0.53	GO:0003677	DNA binding
0.49	GO:0051087	chaperone binding
0.34	GO:0001671	ATPase activator activity
0.34	GO:0043022	ribosome binding
0.33	GO:0031072	heat shock protein binding
0.32	GO:0051082	unfolded protein binding
0.32	GO:0046872	metal ion binding

0.54	GO:0005634	nucleus
0.46	GO:0005783	endoplasmic reticulum
0.40	GO:0005886	plasma membrane
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0031984	organelle subcompartment
0.34	GO:0031967	organelle envelope
0.34	GO:0031090	organelle membrane
0.34	GO:0043233	organelle lumen
0.30	GO:0031224	intrinsic component of membrane

tr|T1G560|T1G560_HELRO
Protein Wnt
Search

0.77	GO:0016055	Wnt signaling pathway
0.70	GO:0007275	multicellular organism development
0.42	GO:0045165	cell fate commitment
0.39	GO:0040028	regulation of vulval development
0.39	GO:0046662	regulation of oviposition
0.38	GO:0007548	sex differentiation
0.38	GO:0030335	positive regulation of cell migration
0.38	GO:0010720	positive regulation of cell development
0.38	GO:0051962	positive regulation of nervous system development
0.37	GO:0007163	establishment or maintenance of cell polarity

0.73	GO:0005102	receptor binding
0.35	GO:0004713	protein tyrosine kinase activity
0.34	GO:0003777	microtubule motor activity
0.34	GO:0008017	microtubule binding
0.34	GO:0003779	actin binding
0.33	GO:0005328	neurotransmitter:sodium symporter activity
0.33	GO:0030545	receptor regulator activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.75	GO:0005578	proteinaceous extracellular matrix
0.39	GO:0005615	extracellular space
0.35	GO:0016459	myosin complex
0.30	GO:0016020	membrane

0.35

GO:0004713

tr|T1G561|T1G561_HELRO
Uncharacterized protein
Search

tr|T1G562|T1G562_HELRO
Uncharacterized protein
Search

0.10	Zinc finger, C2H2 type domain-containing protein (Fragment)

0.43	GO:0090278	negative regulation of peptide hormone secretion
0.38	GO:0006366	transcription by RNA polymerase II
0.38	GO:0022008	neurogenesis
0.36	GO:0007165	signal transduction
0.35	GO:1903506	regulation of nucleic acid-templated transcription
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression
0.34	GO:0030178	negative regulation of Wnt signaling pathway
0.34	GO:0198738	cell-cell signaling by wnt

0.51	GO:0003676	nucleic acid binding
0.36	GO:0003700	DNA binding transcription factor activity
0.34	GO:0008013	beta-catenin binding
0.33	GO:0046872	metal ion binding
0.33	GO:0016817	hydrolase activity, acting on acid anhydrides
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.36	GO:0005634	nucleus
0.36	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.33

EC:3.6

GO:0016817

tr|T1G563|T1G563_HELRO
Uncharacterized protein
Search

0.60	GO:0007018	microtubule-based movement
0.50	GO:0007165	signal transduction
0.42	GO:0009966	regulation of signal transduction
0.42	GO:0043547	positive regulation of GTPase activity
0.40	GO:0023056	positive regulation of signaling
0.40	GO:0010647	positive regulation of cell communication
0.40	GO:0048584	positive regulation of response to stimulus
0.38	GO:0008045	motor neuron axon guidance
0.38	GO:0050770	regulation of axonogenesis
0.37	GO:0023057	negative regulation of signaling

0.61	GO:0003777	microtubule motor activity
0.61	GO:0008017	microtubule binding
0.60	GO:0003779	actin binding
0.47	GO:0032555	purine ribonucleotide binding
0.47	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0030554	adenyl nucleotide binding
0.46	GO:0008144	drug binding
0.42	GO:0005096	GTPase activator activity
0.42	GO:0035591	signaling adaptor activity
0.39	GO:0015293	symporter activity

0.62	GO:0016459	myosin complex
0.33	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1G564|T1G564_HELRO
Uncharacterized protein
Search

0.62	EF-hand domain-containing protein 1

0.50	GO:1990830	cellular response to leukemia inhibitory factor
0.45	GO:0007399	nervous system development
0.44	GO:0007528	neuromuscular junction development
0.44	GO:0050773	regulation of dendrite development
0.43	GO:0010769	regulation of cell morphogenesis involved in differentiation
0.42	GO:0007052	mitotic spindle organization
0.42	GO:0048589	developmental growth
0.42	GO:0120035	regulation of plasma membrane bounded cell projection organization
0.42	GO:0051960	regulation of nervous system development
0.42	GO:0000281	mitotic cytokinesis

0.66	GO:0005509	calcium ion binding
0.44	GO:0043014	alpha-tubulin binding
0.33	GO:0005096	GTPase activator activity

0.44	GO:0043195	terminal bouton
0.44	GO:0015630	microtubule cytoskeleton
0.43	GO:0044430	cytoskeletal part
0.43	GO:0043025	neuronal cell body
0.43	GO:0030425	dendrite
0.41	GO:0099512	supramolecular fiber
0.39	GO:0031514	motile cilium
0.30	GO:0031224	intrinsic component of membrane

tr|T1G565|T1G565_HELRO
Uncharacterized protein
Search

0.37	Phosphoserine phosphatase

0.68	GO:0016311	dephosphorylation
0.59	GO:0006564	L-serine biosynthetic process

0.82	GO:0004647	phosphoserine phosphatase activity
0.33	GO:0046872	metal ion binding

0.82

EC:3.1.3.3

GO:0004647

tr|T1G566|T1G566_HELRO
Uncharacterized protein
Search

HSD17B12

0.68	Very-long-chain 3-oxoacyl-CoA reductase-B

0.49	GO:0010811	positive regulation of cell-substrate adhesion
0.48	GO:0055114	oxidation-reduction process
0.48	GO:0030198	extracellular matrix organization
0.44	GO:0006703	estrogen biosynthetic process
0.42	GO:0006633	fatty acid biosynthetic process
0.38	GO:0061370	testosterone biosynthetic process
0.37	GO:0033555	multicellular organismal response to stress
0.37	GO:0030539	male genitalia development
0.35	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling
0.35	GO:0032876	negative regulation of DNA endoreduplication

0.51	GO:0001968	fibronectin binding
0.49	GO:0016491	oxidoreductase activity
0.49	GO:0005518	collagen binding
0.48	GO:0008201	heparin binding
0.35	GO:0004197	cysteine-type endopeptidase activity
0.33	GO:0016757	transferase activity, transferring glycosyl groups

0.46	GO:0005578	proteinaceous extracellular matrix
0.43	GO:0005783	endoplasmic reticulum
0.42	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.41	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.49

GO:0016491

tr|T1G567|T1G567_HELRO
Uncharacterized protein
Search

DDX24

0.50	ATP-dependent RNA helicase

0.44	GO:0010501	RNA secondary structure unwinding
0.33	GO:0006364	rRNA processing

0.62	GO:0004386	helicase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0003676	nucleic acid binding
0.43	GO:0008186	RNA-dependent ATPase activity
0.39	GO:0140098	catalytic activity, acting on RNA
0.34	GO:0008146	sulfotransferase activity

0.44	GO:0005730	nucleolus
0.35	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.34

GO:0008146

tr|T1G568|T1G568_HELRO
Uncharacterized protein
Search

LRRC56

0.96	Leucine-rich repeat-containing 56

0.58	GO:0070507	regulation of microtubule cytoskeleton organization
0.52	GO:0007165	signal transduction
0.44	GO:0006470	protein dephosphorylation

0.55	GO:0016500	protein-hormone receptor activity
0.49	GO:0004930	G-protein coupled receptor activity
0.44	GO:0004721	phosphoprotein phosphatase activity

0.30

GO:0031224

intrinsic component of membrane

0.44

GO:0004721

tr|T1G569|T1G569_HELRO
Uncharacterized protein
Search

TACO1

0.87	Translational activator of cytochrome c oxidase I

0.51	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.51	GO:0097659	nucleic acid-templated transcription
0.51	GO:0080090	regulation of primary metabolic process
0.51	GO:0051171	regulation of nitrogen compound metabolic process
0.51	GO:0010468	regulation of gene expression
0.48	GO:0010467	gene expression
0.47	GO:0034645	cellular macromolecule biosynthetic process
0.34	GO:0042558	pteridine-containing compound metabolic process

0.49

GO:0003677

DNA binding

0.50	GO:0005739	mitochondrion
0.49	GO:0005634	nucleus

tr|T1G570|T1G570_HELRO
Mitochondrial GTPase 1
Search

MTG1

0.82	Mitochondrial ribosome-associated GTPase 1

0.40	GO:0042254	ribosome biogenesis
0.40	GO:0044065	regulation of respiratory system process
0.39	GO:0070129	regulation of mitochondrial translation
0.36	GO:0090529	cell septum assembly
0.35	GO:0002098	tRNA wobble uridine modification
0.33	GO:0055114	oxidation-reduction process
0.32	GO:0033750	ribosome localization
0.32	GO:0071428	rRNA-containing ribonucleoprotein complex export from nucleus
0.32	GO:0051656	establishment of organelle localization
0.32	GO:0016072	rRNA metabolic process

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0003924	GTPase activity
0.33	GO:0005515	protein binding
0.33	GO:0046872	metal ion binding
0.33	GO:0016491	oxidoreductase activity
0.32	GO:0003723	RNA binding

0.54	GO:0031966	mitochondrial membrane
0.54	GO:0019866	organelle inner membrane
0.38	GO:0005761	mitochondrial ribosome
0.36	GO:0033588	Elongator holoenzyme complex
0.32	GO:0030687	preribosome, large subunit precursor
0.32	GO:0005730	nucleolus
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0016491

tr|T1G571|T1G571_HELRO
Uncharacterized protein
Search

0.59	ADP ribosylation factor

0.35	GO:0032482	Rab protein signal transduction
0.33	GO:0016192	vesicle-mediated transport
0.32	GO:0015031	protein transport

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0005509	calcium ion binding
0.34	GO:0005515	protein binding
0.32	GO:0003677	DNA binding

0.40	GO:0043025	neuronal cell body
0.39	GO:0045202	synapse
0.38	GO:0005794	Golgi apparatus
0.34	GO:0005770	late endosome
0.33	GO:0000786	nucleosome
0.32	GO:0005634	nucleus
0.32	GO:0020002	host cell plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1G572|T1G572_HELRO
Uncharacterized protein
Search

ENSA

0.90	Alpha-endosulfine

0.82	GO:0032515	negative regulation of phosphoprotein phosphatase activity
0.66	GO:0051301	cell division
0.66	GO:0007049	cell cycle
0.46	GO:0050796	regulation of insulin secretion
0.36	GO:0045722	positive regulation of gluconeogenesis
0.34	GO:0046326	positive regulation of glucose import
0.34	GO:0009749	response to glucose
0.34	GO:0046579	positive regulation of Ras protein signal transduction
0.34	GO:0007212	dopamine receptor signaling pathway
0.34	GO:0007584	response to nutrient

0.83	GO:0004864	protein phosphatase inhibitor activity
0.49	GO:0019870	potassium channel inhibitor activity
0.44	GO:0051721	protein phosphatase 2A binding
0.43	GO:0005102	receptor binding
0.33	GO:0000175	3'-5'-exoribonuclease activity
0.33	GO:0019901	protein kinase binding
0.32	GO:0003676	nucleic acid binding

0.49	GO:0005737	cytoplasm
0.35	GO:0005654	nucleoplasm

0.33

EC:3.1.13

GO:0000175

tr|T1G573|T1G573_HELRO
Transcription elongation factor 1 homolog
Search

ELOF1

0.71	Transcription elongation factor 1 homolog

0.57	GO:0006351	transcription, DNA-templated
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0006414	translational elongation
0.46	GO:0006338	chromatin remodeling
0.44	GO:0051254	positive regulation of RNA metabolic process
0.44	GO:0010557	positive regulation of macromolecule biosynthetic process
0.44	GO:0031328	positive regulation of cellular biosynthetic process
0.33	GO:0006013	mannose metabolic process

0.55	GO:0003746	translation elongation factor activity
0.53	GO:0046872	metal ion binding
0.48	GO:0000993	RNA polymerase II core binding
0.33	GO:0004930	G-protein coupled receptor activity
0.33	GO:0004559	alpha-mannosidase activity
0.32	GO:0030246	carbohydrate binding

0.61	GO:0005634	nucleus
0.42	GO:0031974	membrane-enclosed lumen
0.40	GO:0043234	protein complex
0.39	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:3.2.1.24

GO:0004559

tr|T1G574|T1G574_HELRO
Uncharacterized protein
Search

0.73	serine/threonine-protein phosphatase 6 regulatory subunit 3 isoform X6

0.66	GO:0043666	regulation of phosphoprotein phosphatase activity
0.42	GO:0010469	regulation of receptor activity
0.40	GO:0048208	COPII vesicle coating

0.70	GO:0019903	protein phosphatase binding
0.43	GO:0005179	hormone activity

0.61	GO:0005829	cytosol
0.59	GO:0005654	nucleoplasm
0.49	GO:0005886	plasma membrane
0.40	GO:0005576	extracellular region
0.38	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1G575|T1G575_HELRO
Uncharacterized protein
Search

tr|T1G576|T1G576_HELRO
Uncharacterized protein
Search

0.67	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic
0.47	GO:0006030	chitin metabolic process
0.43	GO:0001189	RNA polymerase I transcriptional preinitiation complex assembly
0.41	GO:0051568	histone H3-K4 methylation
0.39	GO:0043547	positive regulation of GTPase activity
0.35	GO:1903506	regulation of nucleic acid-templated transcription
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression

0.71	GO:0004534	5'-3' exoribonuclease activity
0.48	GO:0003676	nucleic acid binding
0.47	GO:0008061	chitin binding
0.42	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.40	GO:0008859	exoribonuclease II activity
0.39	GO:0005096	GTPase activator activity
0.39	GO:0003779	actin binding
0.38	GO:0003774	motor activity
0.36	GO:0003700	DNA binding transcription factor activity
0.35	GO:0030554	adenyl nucleotide binding

0.57	GO:0005634	nucleus
0.43	GO:0005576	extracellular region
0.41	GO:0031974	membrane-enclosed lumen
0.40	GO:0005667	transcription factor complex
0.40	GO:0034708	methyltransferase complex
0.40	GO:0044446	intracellular organelle part
0.39	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

0.71

EC:3.1.13

GO:0004534

tr|T1G577|T1G577_HELRO
Uncharacterized protein
Search

PPP2R5D

0.59	Serine/threonine protein phosphatase 2A regulatory subunit

0.79	GO:0043666	regulation of phosphoprotein phosphatase activity
0.61	GO:0007165	signal transduction
0.49	GO:0035307	positive regulation of protein dephosphorylation
0.45	GO:0006470	protein dephosphorylation
0.37	GO:1903863	P granule assembly
0.37	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway
0.36	GO:0031952	regulation of protein autophosphorylation
0.36	GO:0007399	nervous system development
0.36	GO:0031346	positive regulation of cell projection organization
0.35	GO:0010720	positive regulation of cell development

0.80	GO:0019888	protein phosphatase regulator activity
0.45	GO:0004721	phosphoprotein phosphatase activity
0.34	GO:0005515	protein binding

0.81	GO:0000159	protein phosphatase type 2A complex
0.34	GO:0005634	nucleus
0.33	GO:0005829	cytosol
0.33	GO:0043233	organelle lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.45

GO:0004721

tr|T1G578|T1G578_HELRO
Uncharacterized protein
Search

0.93	Small subunit ribosomal protein S24

0.36	GO:0006412	translation
0.34	GO:0140053	mitochondrial gene expression
0.34	GO:0035335	peptidyl-tyrosine dephosphorylation
0.32	GO:0055114	oxidation-reduction process

0.37	GO:0003735	structural constituent of ribosome
0.34	GO:0004725	protein tyrosine phosphatase activity
0.34	GO:0003723	RNA binding
0.32	GO:0016491	oxidoreductase activity

0.61	GO:0005739	mitochondrion
0.52	GO:0005840	ribosome
0.38	GO:0031974	membrane-enclosed lumen
0.36	GO:0044446	intracellular organelle part

0.34

GO:0004725

tr|T1G579|T1G579_HELRO
Uncharacterized protein
Search

0.18	dual specificity protein phosphatase 26-like

0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.46	GO:0045454	cell redox homeostasis
0.42	GO:0022900	electron transport chain

0.79	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.75	GO:0004725	protein tyrosine phosphatase activity
0.51	GO:0051015	actin filament binding
0.47	GO:0015035	protein disulfide oxidoreductase activity
0.44	GO:0016757	transferase activity, transferring glycosyl groups
0.43	GO:0009055	electron transfer activity

0.30

GO:0005623

cell

0.79

GO:0008138

tr|T1G580|T1G580_HELRO
Uncharacterized protein
Search

0.56	Transforming growth factor beta like domain protein

0.76	GO:0010469	regulation of receptor activity
0.47	GO:0090100	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
0.45	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
0.44	GO:0071363	cellular response to growth factor stimulus
0.44	GO:0060393	regulation of pathway-restricted SMAD protein phosphorylation
0.43	GO:0071495	cellular response to endogenous stimulus
0.43	GO:0071772	response to BMP
0.43	GO:0048856	anatomical structure development
0.43	GO:0006357	regulation of transcription by RNA polymerase II
0.42	GO:0051173	positive regulation of nitrogen compound metabolic process

0.78	GO:0008083	growth factor activity
0.44	GO:0005160	transforming growth factor beta receptor binding
0.42	GO:0005125	cytokine activity
0.38	GO:0070700	BMP receptor binding
0.37	GO:0005179	hormone activity
0.33	GO:0046983	protein dimerization activity
0.33	GO:0042802	identical protein binding
0.32	GO:0008410	CoA-transferase activity

0.66	GO:0005576	extracellular region
0.37	GO:0097467	type III terminal bouton
0.36	GO:0031045	dense core granule
0.34	GO:0034719	SMN-Sm protein complex
0.33	GO:0048471	perinuclear region of cytoplasm
0.32	GO:0071944	cell periphery
0.30	GO:0016020	membrane

0.32

EC:2.8.3

GO:0008410

tr|T1G581|T1G581_HELRO
Uncharacterized protein
Search

0.82	HIG1 hypoxia inducible domain family member 1A

0.30

GO:0044425

membrane part

tr|T1G582|T1G582_HELRO
Uncharacterized protein
Search

0.73	GO:0071805	potassium ion transmembrane transport
0.70	GO:0034765	regulation of ion transmembrane transport
0.70	GO:0051260	protein homooligomerization
0.34	GO:0006379	mRNA cleavage
0.33	GO:0006817	phosphate ion transport
0.32	GO:0006351	transcription, DNA-templated

0.78	GO:0005249	voltage-gated potassium channel activity
0.34	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.33	GO:0005315	inorganic phosphate transmembrane transporter activity
0.33	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.33	GO:0046872	metal ion binding
0.32	GO:0003676	nucleic acid binding

0.78	GO:0008076	voltage-gated potassium channel complex
0.36	GO:0032809	neuronal cell body membrane
0.36	GO:0032590	dendrite membrane
0.36	GO:0030673	axolemma

0.34

GO:0004114

tr|T1G583|T1G583_HELRO
Uncharacterized protein
Search

0.44	SNF-related serine/threonine-protein kinase

0.63	GO:0006468	protein phosphorylation
0.40	GO:0060217	hemangioblast cell differentiation
0.37	GO:0035556	intracellular signal transduction
0.36	GO:0043066	negative regulation of apoptotic process
0.34	GO:0006885	regulation of pH
0.34	GO:0035725	sodium ion transmembrane transport
0.33	GO:1902600	hydrogen ion transmembrane transport

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0000287	magnesium ion binding
0.34	GO:0015385	sodium:proton antiporter activity

0.37	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|T1G584|T1G584_HELRO
Uncharacterized protein
Search

0.72	Glutamate-gated chloride channel subunit beta

0.61	GO:0007165	signal transduction
0.60	GO:0034220	ion transmembrane transport
0.41	GO:0007601	visual perception
0.40	GO:0006821	chloride transport
0.39	GO:0060078	regulation of postsynaptic membrane potential
0.38	GO:0007268	chemical synaptic transmission
0.36	GO:0042462	eye photoreceptor cell development
0.35	GO:0031987	locomotion involved in locomotory behavior
0.35	GO:0043051	regulation of pharyngeal pumping
0.33	GO:0042493	response to drug

0.76	GO:0005230	extracellular ligand-gated ion channel activity
0.70	GO:0099600	transmembrane receptor activity
0.65	GO:0038023	signaling receptor activity
0.40	GO:0099095	ligand-gated anion channel activity
0.40	GO:0005254	chloride channel activity
0.35	GO:0019904	protein domain specific binding
0.32	GO:0008144	drug binding
0.32	GO:0003676	nucleic acid binding
0.32	GO:0016787	hydrolase activity

0.55	GO:0005886	plasma membrane
0.42	GO:1902711	GABA-A receptor complex
0.40	GO:0098794	postsynapse
0.37	GO:0034707	chloride channel complex
0.36	GO:0030054	cell junction
0.34	GO:0030424	axon

0.32

GO:0016787

tr|T1G585|T1G585_HELRO
Uncharacterized protein
Search

CDPF1

0.93	Cysteine-rich DPF motif domain-containing protein 1

0.30

GO:0044425

membrane part

tr|T1G586|T1G586_HELRO
Uncharacterized protein
Search

0.86	Med26 domain containing protein

0.39	GO:2001253	regulation of histone H3-K36 trimethylation
0.38	GO:0010793	regulation of mRNA export from nucleus
0.37	GO:0050684	regulation of mRNA processing
0.36	GO:0032784	regulation of DNA-templated transcription, elongation
0.35	GO:0000027	ribosomal large subunit assembly
0.34	GO:0006364	rRNA processing
0.34	GO:0006464	cellular protein modification process
0.33	GO:0016311	dephosphorylation
0.33	GO:0055085	transmembrane transport
0.33	GO:0016310	phosphorylation

0.34	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.34	GO:0004692	cGMP-dependent protein kinase activity
0.34	GO:0004725	protein tyrosine phosphatase activity
0.33	GO:0031418	L-ascorbic acid binding
0.33	GO:0022857	transmembrane transporter activity
0.33	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0005506	iron ion binding

0.61	GO:0005634	nucleus
0.35	GO:0030687	preribosome, large subunit precursor
0.30	GO:0016020	membrane

0.34

GO:0008138

tr|T1G587|T1G587_HELRO
Uncharacterized protein
Search

NFX1

0.91	Nuclear transcription factor, X-box binding 1

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.40	GO:1902679	negative regulation of RNA biosynthetic process
0.38	GO:0006366	transcription by RNA polymerase II
0.36	GO:0045347	negative regulation of MHC class II biosynthetic process

0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.50	GO:0003676	nucleic acid binding
0.32	GO:0016874	ligase activity
0.31	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.37	GO:0005829	cytosol
0.37	GO:0031974	membrane-enclosed lumen
0.35	GO:0043232	intracellular non-membrane-bounded organelle
0.35	GO:0044446	intracellular organelle part
0.35	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016874

tr|T1G588|T1G588_HELRO
Uncharacterized protein
Search

CDK8

0.84	Cell division protein kinase 8

0.63	GO:0006468	protein phosphorylation
0.43	GO:0045498	sex comb development
0.42	GO:0036011	imaginal disc-derived leg segmentation
0.42	GO:0007346	regulation of mitotic cell cycle
0.42	GO:0022416	chaeta development
0.42	GO:0000082	G1/S transition of mitotic cell cycle
0.41	GO:0034472	snRNA 3'-end processing
0.40	GO:0007411	axon guidance
0.39	GO:0051301	cell division
0.35	GO:0006367	transcription initiation from RNA polymerase II promoter

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0060089	molecular transducer activity
0.34	GO:0005515	protein binding
0.34	GO:0001104	RNA polymerase II transcription cofactor activity
0.32	GO:0003676	nucleic acid binding

0.52	GO:0016592	mediator complex
0.46	GO:0005730	nucleolus
0.33	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

tr|T1G589|T1G589_HELRO
Uncharacterized protein
Search

DUSP21

0.86	Dual specificity phosphatase 21 (Fragment)

0.72	GO:0006470	protein dephosphorylation
0.37	GO:0009968	negative regulation of signal transduction
0.37	GO:0044092	negative regulation of molecular function
0.36	GO:0043405	regulation of MAP kinase activity
0.36	GO:0039514	suppression by virus of host JAK-STAT cascade
0.36	GO:0001933	negative regulation of protein phosphorylation
0.35	GO:0075112	modulation by symbiont of host transmembrane receptor-mediated signal transduction
0.35	GO:0060338	regulation of type I interferon-mediated signaling pathway
0.35	GO:0060761	negative regulation of response to cytokine stimulus
0.35	GO:0075111	negative regulation by symbiont of host receptor-mediated signal transduction

0.78	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.69	GO:0004725	protein tyrosine phosphatase activity
0.37	GO:0033549	MAP kinase phosphatase activity
0.36	GO:0051015	actin filament binding
0.35	GO:0016301	kinase activity

0.34	GO:0030430	host cell cytoplasm
0.34	GO:0019012	virion

0.78

GO:0008138

tr|T1G590|T1G590_HELRO
Uncharacterized protein
Search

0.55

GO:0055085

transmembrane transport

0.57	GO:0022857	transmembrane transporter activity
0.33	GO:0030246	carbohydrate binding

0.30

GO:0044425

membrane part

tr|T1G591|T1G591_HELRO
Uncharacterized protein
Search

tr|T1G592|T1G592_HELRO
Uncharacterized protein
Search

0.45	GO:0045665	negative regulation of neuron differentiation
0.44	GO:2001141	regulation of RNA biosynthetic process
0.44	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.44	GO:0010468	regulation of gene expression
0.44	GO:0043065	positive regulation of apoptotic process
0.41	GO:0040034	regulation of development, heterochronic
0.40	GO:2000797	regulation of amniotic stem cell differentiation
0.40	GO:2000740	negative regulation of mesenchymal stem cell differentiation
0.40	GO:2000065	negative regulation of cortisol biosynthetic process
0.40	GO:0032345	negative regulation of aldosterone metabolic process

0.51	GO:0003676	nucleic acid binding
0.45	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.42	GO:0046872	metal ion binding
0.39	GO:0015271	outward rectifier potassium channel activity
0.37	GO:0008134	transcription factor binding
0.36	GO:0003682	chromatin binding
0.34	GO:0032403	protein complex binding
0.33	GO:0003735	structural constituent of ribosome

0.43	GO:0005634	nucleus
0.39	GO:0070013	intracellular organelle lumen
0.38	GO:0017053	transcriptional repressor complex
0.37	GO:0044446	intracellular organelle part
0.35	GO:0005829	cytosol
0.34	GO:0043232	intracellular non-membrane-bounded organelle
0.33	GO:0043234	protein complex
0.33	GO:0030529	intracellular ribonucleoprotein complex

tr|T1G593|T1G593_HELRO
Uncharacterized protein
Search

0.58	GO:0007219	Notch signaling pathway
0.51	GO:0030154	cell differentiation
0.50	GO:0007275	multicellular organism development
0.49	GO:0050793	regulation of developmental process
0.42	GO:1903506	regulation of nucleic acid-templated transcription
0.42	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.42	GO:0045967	negative regulation of growth rate
0.41	GO:0010468	regulation of gene expression
0.40	GO:0046849	bone remodeling
0.40	GO:0009653	anatomical structure morphogenesis

0.70	GO:0005509	calcium ion binding
0.45	GO:0004872	receptor activity
0.37	GO:0008061	chitin binding
0.35	GO:0005112	Notch binding
0.33	GO:0004871	signal transducer activity

0.39	GO:0043235	receptor complex
0.39	GO:0005654	nucleoplasm
0.38	GO:0009986	cell surface
0.38	GO:0005576	extracellular region
0.37	GO:0005887	integral component of plasma membrane
0.34	GO:0005581	collagen trimer
0.32	GO:0005739	mitochondrion

tr|T1G594|T1G594_HELRO
Uncharacterized protein
Search

0.63	Rho guanine nucleotide exchange factor 12 (Fragment)

0.77	GO:0035023	regulation of Rho protein signal transduction
0.66	GO:0065009	regulation of molecular function
0.57	GO:0007266	Rho protein signal transduction
0.50	GO:0007186	G-protein coupled receptor signaling pathway
0.32	GO:0022900	electron transport chain
0.32	GO:0045666	positive regulation of neuron differentiation
0.32	GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
0.32	GO:0017148	negative regulation of translation
0.32	GO:0000902	cell morphogenesis
0.32	GO:0000910	cytokinesis

0.78	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.51	GO:0001664	G-protein coupled receptor binding
0.49	GO:0005096	GTPase activator activity
0.44	GO:0046872	metal ion binding
0.33	GO:0020037	heme binding
0.33	GO:0009055	electron transfer activity
0.32	GO:0032947	protein complex scaffold activity
0.32	GO:0016740	transferase activity
0.31	GO:0022857	transmembrane transporter activity

0.45	GO:0005737	cytoplasm
0.32	GO:0030015	CCR4-NOT core complex
0.32	GO:0035770	ribonucleoprotein granule
0.31	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.32

GO:0016740

tr|T1G595|T1G595_HELRO
RNA helicase
Search

DDX31

0.45	RNA helicase

0.47	GO:0010501	RNA secondary structure unwinding
0.46	GO:0042254	ribosome biogenesis
0.35	GO:0016072	rRNA metabolic process
0.35	GO:0034470	ncRNA processing
0.34	GO:0046939	nucleotide phosphorylation

0.66	GO:0004386	helicase activity
0.58	GO:0003723	RNA binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0008186	RNA-dependent ATPase activity
0.40	GO:0140098	catalytic activity, acting on RNA
0.34	GO:0004017	adenylate kinase activity
0.33	GO:0005515	protein binding

0.51	GO:0005730	nucleolus
0.47	GO:0005794	Golgi apparatus
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:2.7.4.3

GO:0004017

tr|T1G596|T1G596_HELRO
Uncharacterized protein
Search

SLC5A6

0.47	Sodium-coupled monocarboxylate transporter

0.55	GO:0055085	transmembrane transport
0.34	GO:0006814	sodium ion transport
0.34	GO:0015878	biotin transport
0.34	GO:0072337	modified amino acid transport
0.33	GO:0006768	biotin metabolic process
0.33	GO:0015939	pantothenate metabolic process
0.33	GO:0042891	antibiotic transport

0.57

GO:0022857

transmembrane transporter activity

0.34	GO:0031526	brush border membrane
0.33	GO:0012506	vesicle membrane
0.33	GO:0005887	integral component of plasma membrane
0.32	GO:0005739	mitochondrion

tr|T1G597|T1G597_HELRO
Uncharacterized protein
Search

0.84	GO:1902751	positive regulation of cell cycle G2/M phase transition
0.75	GO:0035335	peptidyl-tyrosine dephosphorylation
0.51	GO:0045931	positive regulation of mitotic cell cycle
0.50	GO:0007144	female meiosis I
0.49	GO:0001556	oocyte maturation
0.48	GO:0032467	positive regulation of cytokinesis
0.47	GO:0009794	regulation of mitotic cell cycle, embryonic
0.46	GO:0045860	positive regulation of protein kinase activity
0.44	GO:0010256	endomembrane system organization
0.44	GO:0060305	regulation of cell diameter

0.75	GO:0004725	protein tyrosine phosphatase activity
0.47	GO:0019901	protein kinase binding
0.35	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.34	GO:0050699	WW domain binding

0.48	GO:0005819	spindle
0.46	GO:0005813	centrosome
0.44	GO:0005634	nucleus
0.38	GO:0005694	chromosome
0.37	GO:0005737	cytoplasm
0.34	GO:0048475	coated membrane
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0098796	membrane protein complex

0.75

GO:0004725

tr|T1G598|T1G598_HELRO
Uncharacterized protein
Search

DDX27

0.49	ATP dependent RNA helicase

0.40	GO:0010501	RNA secondary structure unwinding
0.37	GO:0006364	rRNA processing
0.33	GO:0016567	protein ubiquitination

0.65	GO:0004386	helicase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0003676	nucleic acid binding
0.40	GO:0008186	RNA-dependent ATPase activity
0.37	GO:0140098	catalytic activity, acting on RNA
0.34	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0016779	nucleotidyltransferase activity

0.41	GO:0005730	nucleolus
0.36	GO:0005694	chromosome
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.33	EC:2.7.7	GO:0016779
0.34	KEGG:R03876	GO:0004842

tr|T1G599|T1G599_HELRO
Uncharacterized protein
Search

0.70	transmembrane protein 234

0.58	GO:0039021	pronephric glomerulus development
0.58	GO:0003094	glomerular filtration

0.30

GO:0016020

membrane

tr|T1G5A0|T1G5A0_HELRO
Uncharacterized protein
Search

0.53

Paxillin

0.81	GO:0007160	cell-matrix adhesion
0.50	GO:0060396	growth hormone receptor signaling pathway
0.50	GO:0051496	positive regulation of stress fiber assembly
0.50	GO:0043542	endothelial cell migration
0.48	GO:0007179	transforming growth factor beta receptor signaling pathway
0.46	GO:0034614	cellular response to reactive oxygen species
0.44	GO:0061055	myotome development
0.39	GO:0001756	somitogenesis
0.39	GO:0007519	skeletal muscle tissue development
0.36	GO:0007045	cell-substrate adherens junction assembly

0.60	GO:0017166	vinculin binding
0.54	GO:0046872	metal ion binding
0.51	GO:0038191	neuropilin binding
0.49	GO:0008013	beta-catenin binding
0.37	GO:0051435	BH4 domain binding
0.37	GO:0005178	integrin binding
0.37	GO:0003712	transcription cofactor activity
0.36	GO:0031625	ubiquitin protein ligase binding
0.36	GO:0019901	protein kinase binding
0.34	GO:0030159	receptor signaling complex scaffold activity

0.68	GO:0005856	cytoskeleton
0.57	GO:0005925	focal adhesion
0.48	GO:0030027	lamellipodium
0.44	GO:0005829	cytosol
0.44	GO:0044446	intracellular organelle part
0.42	GO:0005886	plasma membrane
0.37	GO:0005938	cell cortex
0.35	GO:0043234	protein complex

0.33

EC:2.7.7

GO:0016779

tr|T1G5A1|T1G5A1_HELRO
Uncharacterized protein
Search

tr|T1G5A2|T1G5A2_HELRO
Uncharacterized protein
Search

0.10	Disks large 1 tumor suppressor protein (Fragment)

0.66	GO:0046710	GDP metabolic process
0.63	GO:0046037	GMP metabolic process
0.60	GO:0097120	receptor localization to synapse
0.59	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity
0.59	GO:0043113	receptor clustering
0.57	GO:0007268	chemical synaptic transmission
0.53	GO:0007399	nervous system development
0.48	GO:0019233	sensory perception of pain
0.42	GO:0010923	negative regulation of phosphatase activity
0.41	GO:0050808	synapse organization

0.66	GO:0004385	guanylate kinase activity
0.61	GO:0035255	ionotropic glutamate receptor binding
0.41	GO:0019900	kinase binding
0.39	GO:0046982	protein heterodimerization activity

0.60	GO:0014069	postsynaptic density
0.59	GO:0008328	ionotropic glutamate receptor complex
0.58	GO:0045211	postsynaptic membrane
0.57	GO:0016323	basolateral plasma membrane
0.49	GO:0044224	juxtaparanode region of axon
0.47	GO:0030054	cell junction

0.66

EC:2.7.4.8

GO:0004385

tr|T1G5A3|T1G5A3_HELRO
Diacylglycerol kinase
Search

DGKI

0.40	Diacylglycerol kinase

0.83	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway
0.62	GO:0035556	intracellular signal transduction
0.57	GO:0016310	phosphorylation
0.49	GO:1900452	regulation of long term synaptic depression
0.49	GO:0046959	habituation
0.48	GO:0030258	lipid modification
0.48	GO:0034260	negative regulation of GTPase activity
0.48	GO:0051966	regulation of synaptic transmission, glutamatergic
0.47	GO:0046339	diacylglycerol metabolic process
0.47	GO:0046579	positive regulation of Ras protein signal transduction

0.80	GO:0004143	diacylglycerol kinase activity
0.76	GO:0003951	NAD+ kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0005095	GTPase inhibitor activity
0.44	GO:0017016	Ras GTPase binding
0.38	GO:0001727	lipid kinase activity
0.37	GO:0008022	protein C-terminus binding
0.34	GO:0046872	metal ion binding

0.48	GO:0120025	plasma membrane bounded cell projection
0.47	GO:0032045	guanyl-nucleotide exchange factor complex
0.47	GO:0005654	nucleoplasm
0.45	GO:0036477	somatodendritic compartment
0.45	GO:0048471	perinuclear region of cytoplasm
0.45	GO:0098793	presynapse
0.45	GO:0098794	postsynapse
0.44	GO:0031252	cell leading edge
0.42	GO:0044463	cell projection part
0.39	GO:0060076	excitatory synapse

0.80	EC:2.7.1.107	GO:0004143
0.76	KEGG:R00104	GO:0003951

tr|T1G5A4|T1G5A4_HELRO
Uncharacterized protein
Search

0.76	GO:0009190	cyclic nucleotide biosynthetic process
0.63	GO:0035556	intracellular signal transduction
0.50	GO:0046058	cAMP metabolic process
0.49	GO:0071875	adrenergic receptor signaling pathway
0.49	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.46	GO:0009152	purine ribonucleotide biosynthetic process
0.44	GO:0046068	cGMP metabolic process
0.41	GO:0043547	positive regulation of GTPase activity
0.35	GO:0034199	activation of protein kinase A activity
0.35	GO:2000292	regulation of defecation

0.75	GO:0016849	phosphorus-oxygen lyase activity
0.52	GO:1901265	nucleoside phosphate binding
0.51	GO:0009975	cyclase activity
0.50	GO:0036094	small molecule binding
0.41	GO:0005096	GTPase activator activity
0.33	GO:0046872	metal ion binding
0.33	GO:0008144	drug binding
0.33	GO:0097367	carbohydrate derivative binding
0.33	GO:0043168	anion binding
0.32	GO:0016491	oxidoreductase activity

0.45	GO:0005622	intracellular
0.43	GO:0005887	integral component of plasma membrane
0.38	GO:0043234	protein complex
0.35	GO:0030425	dendrite
0.35	GO:0030424	axon

0.75

GO:0016849

tr|T1G5A5|T1G5A5_HELRO
Uncharacterized protein
Search

0.80	GO:0006182	cGMP biosynthetic process
0.63	GO:0035556	intracellular signal transduction
0.61	GO:0006468	protein phosphorylation
0.44	GO:0050908	detection of light stimulus involved in visual perception
0.40	GO:0042127	regulation of cell proliferation
0.38	GO:0009636	response to toxic substance
0.36	GO:0007168	receptor guanylyl cyclase signaling pathway
0.36	GO:0050893	sensory processing
0.35	GO:0022400	regulation of rhodopsin mediated signaling pathway
0.35	GO:0042048	olfactory behavior

0.81	GO:0004383	guanylate cyclase activity
0.61	GO:0004672	protein kinase activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0004016	adenylate cyclase activity
0.37	GO:0032550	purine ribonucleoside binding
0.37	GO:0032561	guanyl ribonucleotide binding
0.35	GO:0042802	identical protein binding
0.35	GO:0046982	protein heterodimerization activity

0.53	GO:0008074	guanylate cyclase complex, soluble
0.41	GO:0005886	plasma membrane
0.36	GO:0043005	neuron projection
0.36	GO:0009986	cell surface
0.36	GO:0098552	side of membrane
0.35	GO:0005640	nuclear outer membrane
0.35	GO:0120038	plasma membrane bounded cell projection part
0.35	GO:0097731	9+0 non-motile cilium
0.35	GO:0044297	cell body
0.34	GO:0005789	endoplasmic reticulum membrane

0.81

GO:0004383

tr|T1G5A6|T1G5A6_HELRO
Uncharacterized protein
Search

0.55	Inositol 1,4,5-trisphosphate receptor type 1

0.82	GO:0048016	inositol phosphate-mediated signaling
0.77	GO:0006816	calcium ion transport
0.60	GO:0034220	ion transmembrane transport
0.43	GO:0051283	negative regulation of sequestering of calcium ion
0.42	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.41	GO:0046000	positive regulation of ecdysteroid secretion
0.40	GO:0030536	larval feeding behavior
0.40	GO:0007629	flight behavior
0.40	GO:0035071	salivary gland cell autophagic cell death
0.40	GO:0055089	fatty acid homeostasis

0.83	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
0.82	GO:0070679	inositol 1,4,5 trisphosphate binding
0.37	GO:0005509	calcium ion binding
0.35	GO:0035091	phosphatidylinositol binding
0.35	GO:0097110	scaffold protein binding

0.67	GO:0005783	endoplasmic reticulum
0.40	GO:0044295	axonal growth cone
0.36	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0031984	organelle subcompartment
0.36	GO:0043235	receptor complex
0.35	GO:0005886	plasma membrane
0.35	GO:0016528	sarcoplasm
0.34	GO:0043209	myelin sheath
0.34	GO:0005938	cell cortex
0.34	GO:0005730	nucleolus

tr|T1G5A7|T1G5A7_HELRO
Tetraspanin
Search

0.58	Tetraspanin

0.42	GO:0007166	cell surface receptor signaling pathway
0.40	GO:0007298	border follicle cell migration
0.40	GO:0045747	positive regulation of Notch signaling pathway
0.37	GO:1901046	positive regulation of oviposition
0.37	GO:0040026	positive regulation of vulval development
0.37	GO:0042661	regulation of mesodermal cell fate specification
0.37	GO:0045138	nematode male tail tip morphogenesis
0.37	GO:1903846	positive regulation of cellular response to transforming growth factor beta stimulus
0.37	GO:0040019	positive regulation of embryonic development
0.36	GO:0034613	cellular protein localization

0.37	GO:0019899	enzyme binding
0.34	GO:0003743	translation initiation factor activity
0.33	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0016874	ligase activity
0.32	GO:0016787	hydrolase activity

0.41	GO:0005887	integral component of plasma membrane
0.35	GO:0030659	cytoplasmic vesicle membrane
0.34	GO:0000151	ubiquitin ligase complex

0.33	EC:6	GO:0016874
0.33	KEGG:R03876	GO:0004842

tr|T1G5A8|T1G5A8_HELRO
Uncharacterized protein
Search

tr|T1G5A9|T1G5A9_HELRO
Uncharacterized protein
Search

DPH1

0.70	Diphthamide biosynthesis protein 1

0.83	GO:0017182	peptidyl-diphthamide metabolic process
0.82	GO:1900247	regulation of cytoplasmic translational elongation
0.49	GO:0044249	cellular biosynthetic process
0.47	GO:0008283	cell proliferation

0.34	GO:0005515	protein binding
0.34	GO:0016740	transferase activity

0.46	GO:0030054	cell junction
0.44	GO:0005654	nucleoplasm
0.33	GO:0005737	cytoplasm

0.34

GO:0016740

tr|T1G5B0|T1G5B0_HELRO
Uncharacterized protein
Search

0.47	WD repeat domain 62

0.74

GO:0008380

RNA splicing

0.59

GO:0003723

RNA binding

0.85	GO:0071011	precatalytic spliceosome
0.84	GO:0005682	U5 snRNP
0.82	GO:0071013	catalytic step 2 spliceosome

tr|T1G5B1|T1G5B1_HELRO
Uncharacterized protein
Search

0.87	Tetratricopeptide repeat protein 39B

0.47

GO:0055085

transmembrane transport

0.54	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.47	GO:0030554	adenyl nucleotide binding
0.46	GO:0097367	carbohydrate derivative binding
0.46	GO:0008144	drug binding
0.46	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0005509	calcium ion binding
0.39	GO:0005515	protein binding

0.30

GO:0031224

intrinsic component of membrane

tr|T1G5B2|T1G5B2_HELRO
Uncharacterized protein
Search

0.52	Fibrinogen

0.65	GO:0043654	recognition of apoptotic cell
0.64	GO:0046597	negative regulation of viral entry into host cell
0.60	GO:0001867	complement activation, lectin pathway
0.53	GO:0051607	defense response to virus
0.50	GO:0002752	cell surface pattern recognition receptor signaling pathway
0.50	GO:1902679	negative regulation of RNA biosynthetic process
0.49	GO:2000484	positive regulation of interleukin-8 secretion
0.48	GO:0034394	protein localization to cell surface
0.47	GO:0007186	G-protein coupled receptor signaling pathway
0.41	GO:0006508	proteolysis

0.57	GO:0003823	antigen binding
0.52	GO:0033691	sialic acid binding
0.49	GO:0001664	G-protein coupled receptor binding
0.48	GO:0008329	signaling pattern recognition receptor activity
0.42	GO:0008233	peptidase activity
0.41	GO:0008061	chitin binding
0.40	GO:0030246	carbohydrate binding
0.39	GO:0017171	serine hydrolase activity
0.38	GO:0046982	protein heterodimerization activity
0.37	GO:0004930	G-protein coupled receptor activity

0.49	GO:0031232	extrinsic component of external side of plasma membrane
0.45	GO:0005581	collagen trimer
0.41	GO:1904813	ficolin-1-rich granule lumen
0.41	GO:0034774	secretory granule lumen
0.40	GO:0072562	blood microparticle
0.30	GO:0016021	integral component of membrane

0.42

GO:0008233

tr|T1G5B3|T1G5B3_HELRO
Uncharacterized protein
Search

0.78	GO:0035023	regulation of Rho protein signal transduction
0.66	GO:0065009	regulation of molecular function
0.62	GO:0035556	intracellular signal transduction
0.36	GO:0051491	positive regulation of filopodium assembly
0.36	GO:0050770	regulation of axonogenesis
0.36	GO:0050803	regulation of synapse structure or activity
0.35	GO:0030036	actin cytoskeleton organization

0.78	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.77	GO:0005057	signal transducer activity, downstream of receptor
0.36	GO:0048365	Rac GTPase binding
0.34	GO:0005543	phospholipid binding

0.45	GO:0005622	intracellular
0.35	GO:0045202	synapse
0.35	GO:0030054	cell junction

tr|T1G5B4|T1G5B4_HELRO
Uncharacterized protein
Search

0.44	GO:0006325	chromatin organization
0.43	GO:0065004	protein-DNA complex assembly
0.42	GO:0006323	DNA packaging
0.42	GO:0000209	protein polyubiquitination
0.41	GO:1901666	positive regulation of NAD+ ADP-ribosyltransferase activity
0.41	GO:2000646	positive regulation of receptor catabolic process
0.41	GO:1902966	positive regulation of protein localization to early endosome
0.41	GO:0035563	positive regulation of chromatin binding
0.41	GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining
0.40	GO:0051444	negative regulation of ubiquitin-protein transferase activity

0.55	GO:0008270	zinc ion binding
0.46	GO:0016874	ligase activity
0.42	GO:0044389	ubiquitin-like protein ligase binding
0.41	GO:0097677	STAT family protein binding
0.40	GO:0004842	ubiquitin-protein transferase activity
0.39	GO:0042393	histone binding
0.38	GO:0008047	enzyme activator activity
0.38	GO:0004857	enzyme inhibitor activity
0.37	GO:0030554	adenyl nucleotide binding
0.37	GO:0003677	DNA binding

0.42	GO:0000786	nucleosome
0.40	GO:0005634	nucleus
0.39	GO:0005769	early endosome
0.39	GO:0005764	lysosome
0.37	GO:0005829	cytosol
0.37	GO:0031974	membrane-enclosed lumen
0.35	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.46	EC:6	GO:0016874
0.40	KEGG:R03876	GO:0004842

tr|T1G5B5|T1G5B5_HELRO
Uncharacterized protein
Search

ATP6V1D

0.85	ATPase H+ transporting V1 subunit D

0.63	GO:0061512	protein localization to cilium
0.59	GO:0060271	cilium assembly
0.55	GO:0055085	transmembrane transport

0.66	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.37	GO:0005515	protein binding

0.58	GO:0005813	centrosome
0.57	GO:0033176	proton-transporting V-type ATPase complex
0.57	GO:0005929	cilium
0.43	GO:0005765	lysosomal membrane
0.38	GO:0070062	extracellular exosome

tr|T1G5B6|T1G5B6_HELRO
Uncharacterized protein
Search

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.39	GO:0016573	histone acetylation
0.38	GO:1902679	negative regulation of RNA biosynthetic process

0.43	GO:0003677	DNA binding
0.39	GO:0004402	histone acetyltransferase activity

0.61	GO:0005634	nucleus
0.43	GO:0031248	protein acetyltransferase complex
0.42	GO:0000785	chromatin
0.41	GO:0031974	membrane-enclosed lumen
0.39	GO:0000781	chromosome, telomeric region
0.39	GO:0043234	protein complex
0.38	GO:1904949	ATPase complex

0.39

GO:0004402

tr|T1G5B7|T1G5B7_HELRO
Uncharacterized protein
Search

0.11	Putative ATP-dependent DNA helicase HFM1 (Fragment)

0.42	GO:0002181	cytoplasmic translation
0.40	GO:0006417	regulation of translation
0.38	GO:0010501	RNA secondary structure unwinding

0.57	GO:0004386	helicase activity
0.51	GO:0032559	adenyl ribonucleotide binding
0.50	GO:0008144	drug binding
0.50	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0003676	nucleic acid binding
0.37	GO:0008186	RNA-dependent ATPase activity
0.35	GO:0140098	catalytic activity, acting on RNA

0.43	GO:0042788	polysomal ribosome
0.42	GO:0010494	cytoplasmic stress granule
0.37	GO:0005730	nucleolus
0.30	GO:0031224	intrinsic component of membrane

tr|T1G5B8|T1G5B8_HELRO
Uncharacterized protein
Search

0.46	ATP-dependent RNA helicase

0.46	GO:0010501	RNA secondary structure unwinding
0.45	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.44	GO:0051028	mRNA transport
0.43	GO:0000398	mRNA splicing, via spliceosome
0.43	GO:0006405	RNA export from nucleus
0.42	GO:0046784	viral mRNA export from host cell nucleus
0.42	GO:2000002	negative regulation of DNA damage checkpoint
0.42	GO:0010628	positive regulation of gene expression
0.41	GO:0008340	determination of adult lifespan
0.39	GO:0032784	regulation of DNA-templated transcription, elongation

0.55	GO:0004386	helicase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0003676	nucleic acid binding
0.44	GO:0008186	RNA-dependent ATPase activity
0.42	GO:0043008	ATP-dependent protein binding
0.39	GO:0042802	identical protein binding
0.39	GO:0140098	catalytic activity, acting on RNA
0.39	GO:0008134	transcription factor binding

0.44	GO:0005681	spliceosomal complex
0.42	GO:0005687	U4 snRNP
0.41	GO:0031981	nuclear lumen
0.41	GO:0000346	transcription export complex
0.41	GO:0005688	U6 snRNP
0.39	GO:0005667	transcription factor complex
0.37	GO:0043232	intracellular non-membrane-bounded organelle
0.36	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.32

GO:0016491

tr|T1G5B9|T1G5B9_HELRO
Uncharacterized protein
Search

tr|T1G5C0|T1G5C0_HELRO
Uncharacterized protein
Search

0.54	GO:0008643	carbohydrate transport
0.54	GO:0055085	transmembrane transport

0.43

GO:0005355

glucose transmembrane transporter activity

0.30

GO:0016020

membrane

tr|T1G5C1|T1G5C1_HELRO
Uncharacterized protein
Search

ADCY9

0.46	Adenylate cyclase type 9 (Fragment)

0.76	GO:0009190	cyclic nucleotide biosynthetic process
0.63	GO:0035556	intracellular signal transduction
0.51	GO:0046058	cAMP metabolic process
0.49	GO:0071875	adrenergic receptor signaling pathway
0.48	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.46	GO:0009152	purine ribonucleotide biosynthetic process
0.44	GO:0046068	cGMP metabolic process
0.34	GO:0034199	activation of protein kinase A activity
0.34	GO:0071377	cellular response to glucagon stimulus
0.34	GO:0003091	renal water homeostasis

0.75	GO:0016849	phosphorus-oxygen lyase activity
0.52	GO:0009975	cyclase activity
0.50	GO:1901265	nucleoside phosphate binding
0.49	GO:0036094	small molecule binding
0.34	GO:0046872	metal ion binding
0.33	GO:0005096	GTPase activator activity
0.33	GO:0046982	protein heterodimerization activity
0.33	GO:0008144	drug binding
0.33	GO:0097367	carbohydrate derivative binding
0.33	GO:0043168	anion binding

0.46	GO:0008074	guanylate cyclase complex, soluble
0.43	GO:0005887	integral component of plasma membrane
0.36	GO:0030425	dendrite
0.36	GO:0030424	axon
0.35	GO:0005741	mitochondrial outer membrane

0.75

GO:0016849

tr|T1G5C2|T1G5C2_HELRO
Uncharacterized protein
Search

tr|T1G5C3|T1G5C3_HELRO
Uncharacterized protein
Search

0.46	Fibrinogen

0.51	GO:0051239	regulation of multicellular organismal process
0.50	GO:0007155	cell adhesion
0.49	GO:0002752	cell surface pattern recognition receptor signaling pathway
0.48	GO:0043654	recognition of apoptotic cell
0.48	GO:0045595	regulation of cell differentiation
0.48	GO:0048699	generation of neurons
0.48	GO:0046597	negative regulation of viral entry into host cell
0.47	GO:0034394	protein localization to cell surface
0.47	GO:0033689	negative regulation of osteoblast proliferation
0.46	GO:0002076	osteoblast development

0.48	GO:0033691	sialic acid binding
0.47	GO:0005102	receptor binding
0.47	GO:0008329	signaling pattern recognition receptor activity
0.44	GO:0050839	cell adhesion molecule binding
0.42	GO:0032403	protein complex binding
0.42	GO:0042802	identical protein binding
0.42	GO:0046982	protein heterodimerization activity
0.42	GO:0004930	G-protein coupled receptor activity
0.38	GO:0008233	peptidase activity
0.36	GO:0022857	transmembrane transporter activity

0.48	GO:0031232	extrinsic component of external side of plasma membrane
0.48	GO:0005578	proteinaceous extracellular matrix
0.48	GO:1990026	hippocampal mossy fiber expansion
0.47	GO:0097442	CA3 pyramidal cell dendrite
0.44	GO:0043025	neuronal cell body
0.30	GO:0016021	integral component of membrane

0.38

GO:0008233

tr|T1G5C4|T1G5C4_HELRO
Uncharacterized protein
Search

0.59	E3 ubiquitin-protein ligase ZNRF2

0.44	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.42	GO:0016567	protein ubiquitination
0.33	GO:0055114	oxidation-reduction process

0.58	GO:0016874	ligase activity
0.44	GO:0061630	ubiquitin protein ligase activity
0.38	GO:0046872	metal ion binding
0.36	GO:0004499	N,N-dimethylaniline monooxygenase activity
0.33	GO:0004386	helicase activity
0.32	GO:0003723	RNA binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0031224

intrinsic component of membrane

0.58

GO:0016874

tr|T1G5C5|T1G5C5_HELRO
Uncharacterized protein
Search

0.94	Tubulin polyglutamylase TTLL6 isoform A

0.60	GO:0036211	protein modification process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0003353	positive regulation of cilium movement
0.49	GO:0051013	microtubule severing
0.49	GO:0001578	microtubule bundle formation
0.35	GO:0006904	vesicle docking involved in exocytosis
0.34	GO:0003341	cilium movement
0.34	GO:0060271	cilium assembly
0.32	GO:0055114	oxidation-reduction process

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0070739	protein-glutamic acid ligase activity
0.46	GO:0015631	tubulin binding
0.34	GO:0003884	D-amino-acid oxidase activity

0.49	GO:0036064	ciliary basal body
0.37	GO:0005874	microtubule
0.34	GO:0005829	cytosol

0.52

EC:6.3.2

GO:0070739

tr|T1G5C6|T1G5C6_HELRO
Uncharacterized protein
Search

0.93	small integral membrane protein 8-like

0.30

GO:0044425

membrane part

tr|T1G5C7|T1G5C7_HELRO
Uncharacterized protein
Search

SOX4

0.88	Transcription factor SOX-21

0.46	GO:2000761	positive regulation of N-terminal peptidyl-lysine acetylation
0.46	GO:0032502	developmental process
0.45	GO:0006366	transcription by RNA polymerase II
0.45	GO:0032501	multicellular organismal process
0.45	GO:0045944	positive regulation of transcription by RNA polymerase II
0.45	GO:0046826	negative regulation of protein export from nucleus
0.45	GO:0042769	DNA damage response, detection of DNA damage
0.45	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
0.44	GO:0032024	positive regulation of insulin secretion
0.44	GO:0071333	cellular response to glucose stimulus

0.55	GO:0003677	DNA binding
0.46	GO:0001105	RNA polymerase II transcription coactivator activity
0.45	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.44	GO:0001067	regulatory region nucleic acid binding
0.40	GO:0046982	protein heterodimerization activity
0.35	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.33	GO:0005516	calmodulin binding
0.32	GO:0004672	protein kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding

0.61	GO:0005634	nucleus
0.41	GO:0005667	transcription factor complex
0.39	GO:0070013	intracellular organelle lumen
0.38	GO:0005739	mitochondrion
0.37	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.35

GO:0032440

tr|T1G5C8|T1G5C8_HELRO
Phosphodiesterase
Search

PDE2A

0.56	Phosphodiesterase

0.60	GO:0007165	signal transduction
0.57	GO:0033159	negative regulation of protein import into nucleus, translocation
0.56	GO:0046069	cGMP catabolic process
0.56	GO:0071321	cellular response to cGMP
0.56	GO:0043117	positive regulation of vascular permeability
0.56	GO:0036006	cellular response to macrophage colony-stimulating factor stimulus
0.55	GO:0043116	negative regulation of vascular permeability
0.53	GO:0006198	cAMP catabolic process
0.53	GO:1904613	cellular response to 2,3,7,8-tetrachlorodibenzodioxine
0.51	GO:0035690	cellular response to drug

0.79	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.54	GO:0030553	cGMP binding
0.54	GO:0046872	metal ion binding
0.52	GO:0030911	TPR domain binding
0.50	GO:0030552	cAMP binding
0.46	GO:0042803	protein homodimerization activity
0.40	GO:0008144	drug binding
0.37	GO:0036004	GAF domain binding
0.36	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.35	GO:0005096	GTPase activator activity

0.50	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0005741	mitochondrial outer membrane
0.45	GO:0005829	cytosol
0.43	GO:0042734	presynaptic membrane
0.43	GO:0005634	nucleus
0.42	GO:0005743	mitochondrial inner membrane
0.41	GO:0005759	mitochondrial matrix
0.40	GO:0005794	Golgi apparatus
0.40	GO:0005783	endoplasmic reticulum
0.36	GO:0030425	dendrite

0.79

GO:0004114

tr|T1G5C9|T1G5C9_HELRO
Uncharacterized protein
Search

0.10	Homeobox protein HMX3 (Fragment)

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.49	GO:0090596	sensory organ morphogenesis
0.49	GO:0050885	neuromuscular process controlling balance
0.48	GO:0007566	embryo implantation
0.48	GO:0048839	inner ear development
0.48	GO:0060135	maternal process involved in female pregnancy
0.48	GO:0007399	nervous system development
0.47	GO:0048562	embryonic organ morphogenesis

0.65	GO:0043565	sequence-specific DNA binding
0.48	GO:0001012	RNA polymerase II regulatory region DNA binding
0.46	GO:0003690	double-stranded DNA binding
0.41	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|T1G5D0|T1G5D0_HELRO
Uncharacterized protein
Search

PRKX

0.67	cAMP-dependent protein kinase catalytic subunit PRKX

0.63	GO:0006468	protein phosphorylation
0.46	GO:0060562	epithelial tube morphogenesis
0.45	GO:0009887	animal organ morphogenesis
0.44	GO:0035120	post-embryonic appendage morphogenesis
0.44	GO:0035114	imaginal disc-derived appendage morphogenesis
0.44	GO:0035220	wing disc development
0.44	GO:0048707	instar larval or pupal morphogenesis
0.44	GO:0007552	metamorphosis
0.44	GO:0048569	post-embryonic animal organ development
0.41	GO:0001935	endothelial cell proliferation

0.70	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0060089	molecular transducer activity
0.36	GO:0034237	protein kinase A regulatory subunit binding
0.34	GO:0004871	signal transducer activity

0.37	GO:0005952	cAMP-dependent protein kinase complex
0.36	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.70

GO:0004674

tr|T1G5D1|T1G5D1_HELRO
Uncharacterized protein
Search

0.66	La ribonucleoprotein domain family, member 1

0.36	GO:0072752	cellular response to rapamycin
0.36	GO:1990928	response to amino acid starvation
0.35	GO:0038202	TORC1 signaling
0.35	GO:0045070	positive regulation of viral genome replication
0.35	GO:0048255	mRNA stabilization
0.35	GO:0016239	positive regulation of macroautophagy
0.34	GO:0008283	cell proliferation
0.34	GO:0045727	positive regulation of translation
0.34	GO:0006396	RNA processing
0.34	GO:0017148	negative regulation of translation

0.58	GO:0003723	RNA binding
0.35	GO:0008494	translation activator activity
0.35	GO:0008190	eukaryotic initiation factor 4E binding
0.35	GO:0045296	cadherin binding
0.34	GO:0008270	zinc ion binding

0.47	GO:0019013	viral nucleocapsid
0.44	GO:0030529	intracellular ribonucleoprotein complex
0.35	GO:0031931	TORC1 complex
0.34	GO:0005634	nucleus
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.32	GO:0044444	cytoplasmic part
0.30	GO:0016021	integral component of membrane

tr|T1G5D2|T1G5D2_HELRO
Uncharacterized protein
Search

MRPS18C

0.60	Mitochondrial ribosomal protein S18C

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.36	GO:0051013	microtubule severing
0.34	GO:0051301	cell division
0.34	GO:0007049	cell cycle
0.34	GO:0043412	macromolecule modification
0.33	GO:0032259	methylation
0.32	GO:0016070	RNA metabolic process

0.64	GO:0003735	structural constituent of ribosome
0.36	GO:0008568	microtubule-severing ATPase activity
0.35	GO:0008017	microtubule binding
0.34	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0008173	RNA methyltransferase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003723	RNA binding

0.61	GO:0005840	ribosome
0.40	GO:0005759	mitochondrial matrix
0.39	GO:0044445	cytosolic part
0.35	GO:0000922	spindle pole
0.35	GO:0005813	centrosome
0.34	GO:0005874	microtubule

0.36	EC:3.6.4.3	GO:0008568
0.34	KEGG:R03876	GO:0004842

tr|T1G5D3|T1G5D3_HELRO
Uncharacterized protein
Search

0.57	Fibrinogen

0.68	GO:0042127	regulation of cell proliferation
0.65	GO:0007155	cell adhesion
0.48	GO:0031103	axon regeneration
0.45	GO:0048680	positive regulation of axon regeneration
0.45	GO:0021554	optic nerve development
0.45	GO:0045887	positive regulation of synaptic growth at neuromuscular junction
0.45	GO:0030517	negative regulation of axon extension
0.45	GO:0007413	axonal fasciculation
0.45	GO:0030199	collagen fibril organization
0.44	GO:0001755	neural crest cell migration

0.41	GO:0045545	syndecan binding
0.34	GO:0005178	integrin binding
0.33	GO:0042802	identical protein binding
0.32	GO:0022857	transmembrane transporter activity

0.68	GO:0031012	extracellular matrix
0.38	GO:0005615	extracellular space
0.35	GO:1990026	hippocampal mossy fiber expansion
0.35	GO:0097442	CA3 pyramidal cell dendrite
0.34	GO:0043025	neuronal cell body
0.34	GO:0009986	cell surface
0.30	GO:0016020	membrane

tr|T1G5D4|T1G5D4_HELRO
Uncharacterized protein
Search

0.45	GO:0032501	multicellular organismal process
0.45	GO:0006468	protein phosphorylation
0.44	GO:0048856	anatomical structure development
0.44	GO:0051045	negative regulation of membrane protein ectodomain proteolysis
0.44	GO:2000010	positive regulation of protein localization to cell surface
0.44	GO:0010640	regulation of platelet-derived growth factor receptor signaling pathway
0.44	GO:0120035	regulation of plasma membrane bounded cell projection organization
0.43	GO:0030334	regulation of cell migration
0.43	GO:0051960	regulation of nervous system development
0.43	GO:0060284	regulation of cell development

0.54	GO:0005509	calcium ion binding
0.45	GO:0004672	protein kinase activity
0.41	GO:0030554	adenyl nucleotide binding
0.41	GO:0097367	carbohydrate derivative binding
0.41	GO:0008144	drug binding
0.41	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0005102	receptor binding
0.39	GO:0008046	axon guidance receptor activity
0.39	GO:0003823	antigen binding
0.37	GO:0042803	protein homodimerization activity

0.49	GO:0005604	basement membrane
0.47	GO:0005938	cell cortex
0.46	GO:0030054	cell junction
0.44	GO:0043005	neuron projection
0.44	GO:0043025	neuronal cell body
0.44	GO:0120038	plasma membrane bounded cell projection part
0.42	GO:0031982	vesicle
0.41	GO:0030427	site of polarized growth
0.38	GO:0043230	extracellular organelle
0.37	GO:0005615	extracellular space

0.34

GO:0004725

tr|T1G5D5|T1G5D5_HELRO
Uncharacterized protein
Search

CTR9

0.76	RNA polymerase-associated protein CTR9

0.74	GO:0016570	histone modification
0.59	GO:2001162	positive regulation of histone H3-K79 methylation
0.58	GO:0051569	regulation of histone H3-K4 methylation
0.57	GO:2001168	positive regulation of histone H2B ubiquitination
0.57	GO:2000653	regulation of genetic imprinting
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1900364	negative regulation of mRNA polyadenylation
0.56	GO:0070102	interleukin-6-mediated signaling pathway
0.56	GO:0001711	endodermal cell fate commitment

0.55	GO:0042169	SH2 domain binding
0.48	GO:0000993	RNA polymerase II core binding
0.34	GO:0046982	protein heterodimerization activity
0.32	GO:0022857	transmembrane transporter activity
0.32	GO:0003677	DNA binding

0.58	GO:0016593	Cdc73/Paf1 complex
0.55	GO:0035327	transcriptionally active chromatin
0.36	GO:0016607	nuclear speck
0.34	GO:0000786	nucleosome
0.30	GO:0016020	membrane

tr|T1G5D6|T1G5D6_HELRO
Uncharacterized protein
Search

0.57	Fibrinogen

0.68	GO:0042127	regulation of cell proliferation
0.65	GO:0007155	cell adhesion
0.49	GO:0031103	axon regeneration
0.45	GO:0009888	tissue development
0.44	GO:0048680	positive regulation of axon regeneration
0.44	GO:0021554	optic nerve development
0.44	GO:0045887	positive regulation of synaptic growth at neuromuscular junction
0.44	GO:0060739	mesenchymal-epithelial cell signaling involved in prostate gland development
0.44	GO:0030517	negative regulation of axon extension
0.44	GO:0007413	axonal fasciculation

0.43	GO:0045545	syndecan binding
0.34	GO:0001968	fibronectin binding
0.34	GO:0005178	integrin binding
0.33	GO:0042802	identical protein binding
0.33	GO:0004930	G-protein coupled receptor activity

0.68	GO:0031012	extracellular matrix
0.39	GO:0005615	extracellular space
0.35	GO:0005925	focal adhesion
0.35	GO:1990026	hippocampal mossy fiber expansion
0.35	GO:0097442	CA3 pyramidal cell dendrite
0.34	GO:0043025	neuronal cell body
0.33	GO:0009986	cell surface
0.30	GO:0016020	membrane

tr|T1G5D7|T1G5D7_HELRO
Uncharacterized protein
Search

0.23	RNA recognition motif

0.35	GO:0072423	response to DNA damage checkpoint signaling
0.35	GO:0098789	pre-mRNA cleavage required for polyadenylation
0.35	GO:0006368	transcription elongation from RNA polymerase II promoter
0.35	GO:0006378	mRNA polyadenylation
0.34	GO:0034063	stress granule assembly
0.34	GO:0043488	regulation of mRNA stability
0.34	GO:0016570	histone modification
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

0.58

GO:0003723

RNA binding

0.43	GO:0019013	viral nucleocapsid
0.41	GO:0030529	intracellular ribonucleoprotein complex
0.35	GO:0044451	nucleoplasm part
0.34	GO:0043232	intracellular non-membrane-bounded organelle
0.34	GO:0055029	nuclear DNA-directed RNA polymerase complex
0.34	GO:0043234	protein complex
0.34	GO:0044444	cytoplasmic part

tr|T1G5D8|T1G5D8_HELRO
Uncharacterized protein
Search

0.40	Putative amino acid transporter (Fragment)

0.55

GO:0055085

transmembrane transport

0.57

GO:0022857

transmembrane transporter activity

0.30

GO:0044425

membrane part

tr|T1G5D9|T1G5D9_HELRO
Uncharacterized protein
Search

0.48	Calcium-binding mitochondrial carrier protein SCaMC-2-A

0.53	GO:0055085	transmembrane transport
0.43	GO:0015868	purine ribonucleotide transport
0.43	GO:0051503	adenine nucleotide transport
0.41	GO:0006839	mitochondrial transport
0.41	GO:0006508	proteolysis
0.39	GO:0015893	drug transport
0.39	GO:0015711	organic anion transport
0.35	GO:0071277	cellular response to calcium ion
0.34	GO:0034599	cellular response to oxidative stress
0.34	GO:0010941	regulation of cell death

0.64	GO:0005509	calcium ion binding
0.48	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.43	GO:0005346	purine ribonucleotide transmembrane transporter activity
0.43	GO:0000295	adenine nucleotide transmembrane transporter activity
0.40	GO:0008514	organic anion transmembrane transporter activity
0.40	GO:0015238	drug transmembrane transporter activity
0.36	GO:0003723	RNA binding
0.35	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.33	GO:1901682	sulfur compound transmembrane transporter activity
0.33	GO:0016746	transferase activity, transferring acyl groups

0.52	GO:0031966	mitochondrial membrane
0.52	GO:0019866	organelle inner membrane
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.35

GO:0032440

tr|T1G5E0|T1G5E0_HELRO
Uncharacterized protein
Search

tr|T1G5E1|T1G5E1_HELRO
Ubiquitin-fold modifier 1
Search

UFM1

0.89	Ubiquitin-fold modifier 1

0.86	GO:0071569	protein ufmylation
0.62	GO:0033146	regulation of intracellular estrogen receptor signaling pathway
0.62	GO:0034976	response to endoplasmic reticulum stress
0.43	GO:0043066	negative regulation of apoptotic process
0.41	GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus

0.36

GO:0005515

protein binding

0.61	GO:0005634	nucleus
0.53	GO:0005783	endoplasmic reticulum
0.44	GO:0070062	extracellular exosome

tr|T1G5E2|T1G5E2_HELRO
Uncharacterized protein
Search

0.10	Ecdysone-induced protein 74EF (inferred by orthology to a D. melanogaster protein)

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0001787	natural killer cell proliferation
0.54	GO:0001866	NK T cell proliferation
0.49	GO:0045087	innate immune response
0.48	GO:1902680	positive regulation of RNA biosynthetic process
0.41	GO:0032502	developmental process
0.38	GO:0051302	regulation of cell division
0.37	GO:0022414	reproductive process

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity

0.60	GO:0005634	nucleus
0.36	GO:0005829	cytosol
0.36	GO:0031974	membrane-enclosed lumen
0.34	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

tr|T1G5E3|T1G5E3_HELRO
Uncharacterized protein
Search

0.72	Cytosolic endo-beta-N-acetylglucosaminidase

0.41	GO:0006517	protein deglycosylation
0.35	GO:0044041	multi-organism carbohydrate catabolic process
0.35	GO:0044278	cell wall disruption in other organism
0.34	GO:0009617	response to bacterium
0.34	GO:0009253	peptidoglycan catabolic process
0.33	GO:0043043	peptide biosynthetic process
0.33	GO:0006468	protein phosphorylation
0.33	GO:0106074	aminoacyl-tRNA metabolism involved in translational fidelity
0.32	GO:0010467	gene expression
0.32	GO:0034220	ion transmembrane transport

0.85	GO:0033925	mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity
0.35	GO:0016231	beta-N-acetylglucosaminidase activity
0.33	GO:0003735	structural constituent of ribosome
0.33	GO:0004674	protein serine/threonine kinase activity
0.33	GO:0005216	ion channel activity
0.33	GO:0004832	valine-tRNA ligase activity
0.33	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
0.33	GO:0002161	aminoacyl-tRNA editing activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding

0.49	GO:0005737	cytoplasm
0.37	GO:0005581	collagen trimer
0.36	GO:0005576	extracellular region
0.35	GO:0043231	intracellular membrane-bounded organelle
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

0.85	EC:3.2.1.96	GO:0033925
0.33	KEGG:R03665	GO:0004832

tr|T1G5E4|T1G5E4_HELRO
Uncharacterized protein
Search

0.40	Reactive intermediate imine deaminase

0.51	GO:1901565	organonitrogen compound catabolic process
0.48	GO:0017148	negative regulation of translation
0.46	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic

0.56	GO:0019239	deaminase activity
0.50	GO:0016892	endoribonuclease activity, producing 3'-phosphomonoesters

0.49	GO:0005634	nucleus
0.48	GO:0005777	peroxisome
0.48	GO:0005759	mitochondrial matrix
0.30	GO:0031224	intrinsic component of membrane

0.50

EC:3.1.27

GO:0016892

tr|T1G5E5|T1G5E5_HELRO
Uncharacterized protein
Search

tr|T1G5E6|T1G5E6_HELRO
ATP-dependent Clp protease proteolytic subunit
Search

0.42	ATP-dependent Clp protease proteolytic subunit

0.61	GO:0006508	proteolysis
0.42	GO:0032259	methylation
0.36	GO:0044257	cellular protein catabolic process

0.69	GO:0004252	serine-type endopeptidase activity
0.42	GO:0008168	methyltransferase activity

0.39	GO:0009368	endopeptidase Clp complex
0.37	GO:0005759	mitochondrial matrix
0.30	GO:0044425	membrane part

0.69

GO:0004252

tr|T1G5E7|T1G5E7_HELRO
Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial
Search

COQ4

0.70	Ubiquinone biosynthesis protein coq-4, mitochondrial

0.75	GO:0006744	ubiquinone biosynthetic process
0.37	GO:0008643	carbohydrate transport
0.33	GO:0055085	transmembrane transport
0.32	GO:0055114	oxidation-reduction process

0.34	GO:0008270	zinc ion binding
0.34	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.34	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.33	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
0.33	GO:0071949	FAD binding
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.77	GO:0031314	extrinsic component of mitochondrial inner membrane
0.36	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.34

EC:1.14.14

GO:0016712

tr|T1G5E8|T1G5E8_HELRO
Uncharacterized protein
Search

B3GNTL1

0.97	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase protein 1

0.33

GO:0022900

electron transport chain

0.63	GO:0016757	transferase activity, transferring glycosyl groups
0.34	GO:0051537	2 iron, 2 sulfur cluster binding
0.33	GO:0009055	electron transfer activity

0.30

GO:0031224

intrinsic component of membrane

0.63

GO:0016757

tr|T1G5E9|T1G5E9_HELRO
Uncharacterized protein
Search

0.50	Rhabdomeric opsin 3

0.72	GO:0007602	phototransduction
0.72	GO:0007601	visual perception
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.62	GO:0018298	protein-chromophore linkage
0.43	GO:0070472	regulation of uterine smooth muscle contraction
0.43	GO:1902093	positive regulation of flagellated sperm motility
0.38	GO:0045987	positive regulation of smooth muscle contraction
0.37	GO:0007267	cell-cell signaling
0.37	GO:0007596	blood coagulation
0.36	GO:0033685	negative regulation of luteinizing hormone secretion

0.72	GO:0004930	G-protein coupled receptor activity
0.66	GO:0009881	photoreceptor activity
0.47	GO:0001653	peptide receptor activity
0.35	GO:0004896	cytokine receptor activity
0.35	GO:0051916	granulocyte colony-stimulating factor binding
0.33	GO:0016918	retinal binding
0.33	GO:0042277	peptide binding

0.43	GO:0061827	sperm head
0.42	GO:0097225	sperm midpiece
0.38	GO:0005886	plasma membrane
0.33	GO:0001750	photoreceptor outer segment
0.30	GO:0016021	integral component of membrane

tr|T1G5F0|T1G5F0_HELRO
Uncharacterized protein
Search

0.11	Immunoglobulin-binding protein 1

0.70	GO:0009966	regulation of signal transduction
0.47	GO:0043666	regulation of phosphoprotein phosphatase activity
0.45	GO:0007472	wing disc morphogenesis
0.45	GO:0007052	mitotic spindle organization
0.45	GO:0035308	negative regulation of protein dephosphorylation
0.45	GO:0010923	negative regulation of phosphatase activity
0.42	GO:1903361	protein localization to basolateral plasma membrane

0.47	GO:0019888	protein phosphatase regulator activity
0.45	GO:0019212	phosphatase inhibitor activity
0.42	GO:0051721	protein phosphatase 2A binding
0.35	GO:0000062	fatty-acyl-CoA binding

0.44	GO:0000159	protein phosphatase type 2A complex
0.38	GO:0005829	cytosol

tr|T1G5F1|T1G5F1_HELRO
Uncharacterized protein
Search

0.10	Glucose-dependent insulinotropic receptor

0.36	GO:0070647	protein modification by small protein conjugation or removal
0.35	GO:0042073	intraciliary transport
0.34	GO:0060271	cilium assembly
0.34	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:0006508	proteolysis
0.33	GO:0006351	transcription, DNA-templated
0.33	GO:0006313	transposition, DNA-mediated
0.33	GO:0016192	vesicle-mediated transport
0.33	GO:0015074	DNA integration
0.33	GO:0006355	regulation of transcription, DNA-templated

0.35	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.34	GO:0031683	G-protein beta/gamma-subunit complex binding
0.34	GO:0004842	ubiquitin-protein transferase activity
0.34	GO:0015631	tubulin binding
0.33	GO:0003924	GTPase activity
0.33	GO:0003677	DNA binding
0.33	GO:0019001	guanyl nucleotide binding
0.33	GO:0008270	zinc ion binding
0.33	GO:0004871	signal transducer activity
0.33	GO:0003700	DNA binding transcription factor activity

0.35	GO:0030992	intraciliary transport particle B
0.34	GO:0031514	motile cilium
0.34	GO:0030008	TRAPP complex
0.33	GO:0043231	intracellular membrane-bounded organelle
0.32	GO:0044444	cytoplasmic part
0.30	GO:0016020	membrane

0.33	EC:6.3.5	GO:0016884
0.34	KEGG:R03876	GO:0004842

tr|T1G5F2|T1G5F2_HELRO
Uncharacterized protein
Search

tr|T1G5F3|T1G5F3_HELRO
Uncharacterized protein
Search

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.48	GO:0007399	nervous system development
0.45	GO:0007267	cell-cell signaling
0.42	GO:0048513	animal organ development
0.40	GO:0043009	chordate embryonic development
0.39	GO:0007605	sensory perception of sound
0.38	GO:0007626	locomotory behavior
0.38	GO:0030154	cell differentiation
0.38	GO:0009653	anatomical structure morphogenesis
0.38	GO:0009888	tissue development

0.70	GO:0005509	calcium ion binding
0.38	GO:0042802	identical protein binding
0.36	GO:0070097	delta-catenin binding
0.35	GO:0045294	alpha-catenin binding
0.35	GO:0008013	beta-catenin binding
0.34	GO:0004930	G-protein coupled receptor activity
0.33	GO:0004725	protein tyrosine phosphatase activity

0.56	GO:0005886	plasma membrane
0.41	GO:0030054	cell junction
0.39	GO:0032420	stereocilium
0.37	GO:0045202	synapse
0.36	GO:0005783	endoplasmic reticulum
0.35	GO:0045177	apical part of cell
0.34	GO:0030425	dendrite
0.34	GO:0005615	extracellular space
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.33

GO:0004725

tr|T1G5F4|T1G5F4_HELRO
Uncharacterized protein
Search

0.44	Liquid facets (Fragment)

0.68	GO:0006897	endocytosis
0.41	GO:0015032	storage protein import into fat body
0.40	GO:0009997	negative regulation of cardioblast cell fate specification
0.40	GO:1990074	polyuridylation-dependent mRNA catabolic process
0.39	GO:0034427	nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'
0.39	GO:0045747	positive regulation of Notch signaling pathway
0.38	GO:0006914	autophagy
0.38	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic
0.36	GO:0006468	protein phosphorylation

0.38	GO:0000175	3'-5'-exoribonuclease activity
0.36	GO:0004672	protein kinase activity
0.35	GO:0003723	RNA binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0046872	metal ion binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.80	GO:0030128	clathrin coat of endocytic vesicle
0.49	GO:0032009	early phagosome
0.48	GO:0031143	pseudopodium
0.48	GO:0001891	phagocytic cup
0.39	GO:0000932	P-body
0.30	GO:0016021	integral component of membrane

0.38

EC:3.1.13

GO:0000175

tr|T1G5F5|T1G5F5_HELRO
Uncharacterized protein
Search

tr|T1G5F6|T1G5F6_HELRO
Uncharacterized protein
Search

0.54	GO:0050982	detection of mechanical stimulus
0.50	GO:0070588	calcium ion transmembrane transport
0.49	GO:0001822	kidney development
0.44	GO:0098869	cellular oxidant detoxification
0.40	GO:0031659	positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle
0.39	GO:0042994	cytoplasmic sequestering of transcription factor
0.39	GO:0001502	cartilage condensation
0.39	GO:0036303	lymph vessel morphogenesis
0.39	GO:0034405	response to fluid shear stress
0.39	GO:0060428	lung epithelium development

0.68	GO:0005509	calcium ion binding
0.51	GO:0005262	calcium channel activity
0.49	GO:0030246	carbohydrate binding
0.47	GO:0004096	catalase activity
0.42	GO:0020037	heme binding
0.39	GO:0044325	ion channel binding
0.38	GO:0019901	protein kinase binding
0.38	GO:0001965	G-protein alpha-subunit binding
0.37	GO:0019904	protein domain specific binding
0.33	GO:0003676	nucleic acid binding

0.40	GO:0002133	polycystin complex
0.38	GO:0016323	basolateral plasma membrane
0.38	GO:0070062	extracellular exosome
0.38	GO:0031514	motile cilium
0.37	GO:0009986	cell surface
0.35	GO:0005634	nucleus
0.33	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.47

EC:1.11.1.6

GO:0004096

tr|T1G5F7|T1G5F7_HELRO
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8
Search

NDUFA8

0.63	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8

0.75	GO:0006120	mitochondrial electron transport, NADH to ubiquinone
0.38	GO:0032981	mitochondrial respiratory chain complex I assembly
0.36	GO:0006937	regulation of muscle contraction

0.37	GO:0032403	protein complex binding
0.34	GO:0016491	oxidoreductase activity

0.81	GO:0005747	mitochondrial respiratory chain complex I
0.37	GO:0005758	mitochondrial intermembrane space
0.36	GO:0005861	troponin complex

0.34

GO:0016491

tr|T1G5F8|T1G5F8_HELRO
Uncharacterized protein
Search

ISCA1

0.96	Iron-sulfur cluster assembly 1 like protein, mitochondrial

0.78	GO:0097428	protein maturation by iron-sulfur cluster transfer
0.44	GO:0016226	iron-sulfur cluster assembly
0.38	GO:0006783	heme biosynthetic process
0.35	GO:0050886	endocrine process
0.32	GO:0044281	small molecule metabolic process

0.64	GO:0051536	iron-sulfur cluster binding
0.62	GO:0005198	structural molecule activity
0.46	GO:0008198	ferrous iron binding
0.36	GO:0050265	RNA uridylyltransferase activity
0.35	GO:0008270	zinc ion binding
0.33	GO:0003676	nucleic acid binding

0.45

GO:0005759

mitochondrial matrix

0.36

EC:2.7.7.52

GO:0050265

tr|T1G5F9|T1G5F9_HELRO
Non-specific serine/threonine protein kinase
Search

0.38	Non-specific serine/threonine protein kinase

0.79	GO:0030010	establishment of cell polarity
0.74	GO:0000226	microtubule cytoskeleton organization
0.62	GO:0006468	protein phosphorylation
0.34	GO:0001764	neuron migration
0.33	GO:0035556	intracellular signal transduction

0.68	GO:0004674	protein serine/threonine kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0050321	tau-protein kinase activity
0.33	GO:0000287	magnesium ion binding

0.33	GO:0005856	cytoskeleton
0.32	GO:0005737	cytoplasm

0.68

GO:0004674

tr|T1G5G0|T1G5G0_HELRO
Uncharacterized protein
Search

0.38	Arginine/serine-rich splicing factor

0.36	GO:0043484	regulation of RNA splicing
0.36	GO:0097421	liver regeneration
0.35	GO:0032869	cellular response to insulin stimulus
0.35	GO:0051726	regulation of cell cycle
0.34	GO:0001178	regulation of transcriptional start site selection at RNA polymerase II promoter
0.34	GO:0051254	positive regulation of RNA metabolic process
0.34	GO:0010628	positive regulation of gene expression
0.34	GO:0031440	regulation of mRNA 3'-end processing
0.33	GO:0051607	defense response to virus
0.33	GO:1903047	mitotic cell cycle process

0.59	GO:0003723	RNA binding
0.36	GO:0043422	protein kinase B binding
0.33	GO:0016603	glutaminyl-peptide cyclotransferase activity
0.33	GO:0003899	DNA-directed 5'-3' RNA polymerase activity

0.41	GO:0005730	nucleolus
0.40	GO:0005829	cytosol
0.34	GO:0035062	omega speckle
0.34	GO:0035327	transcriptionally active chromatin
0.34	GO:0071011	precatalytic spliceosome
0.34	GO:0005700	polytene chromosome
0.34	GO:0071013	catalytic step 2 spliceosome
0.30	GO:0016020	membrane

0.33

EC:2.3.2.5

GO:0016603

tr|T1G5G1|T1G5G1_HELRO
Uncharacterized protein
Search

RPRD1B

0.90	regulation of nuclear pre-mRNA domain-containing protein 1B

0.85	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain
0.72	GO:0008284	positive regulation of cell proliferation
0.69	GO:0010564	regulation of cell cycle process
0.68	GO:0045944	positive regulation of transcription by RNA polymerase II
0.41	GO:0042795	snRNA transcription by RNA polymerase II
0.36	GO:0006882	cellular zinc ion homeostasis
0.36	GO:0071577	zinc II ion transmembrane transport
0.35	GO:0006913	nucleocytoplasmic transport
0.34	GO:0015031	protein transport
0.33	GO:0016310	phosphorylation

0.78	GO:0000993	RNA polymerase II core binding
0.68	GO:0042802	identical protein binding
0.36	GO:0005385	zinc ion transmembrane transporter activity
0.34	GO:0003924	GTPase activity
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0019001	guanyl nucleotide binding
0.34	GO:0016301	kinase activity
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.75	GO:0016591	DNA-directed RNA polymerase II, holoenzyme
0.71	GO:0005813	centrosome
0.63	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|T1G5G2|T1G5G2_HELRO
Prefoldin subunit 4
Search

PFDN4

0.75	Prefoldin subunit 4

0.68

GO:0006457

protein folding

0.70	GO:0051082	unfolded protein binding
0.45	GO:0051087	chaperone binding

0.79	GO:0016272	prefoldin complex
0.42	GO:0005634	nucleus
0.42	GO:0005739	mitochondrion
0.34	GO:0005829	cytosol

tr|T1G5G3|T1G5G3_HELRO
Uncharacterized protein
Search

VPS54

0.94	Vacuolar protein sorting-associated protein 54

0.80	GO:0042147	retrograde transport, endosome to Golgi
0.57	GO:0060052	neurofilament cytoskeleton organization
0.56	GO:0048873	homeostasis of number of cells within a tissue
0.56	GO:0050881	musculoskeletal movement
0.56	GO:0007041	lysosomal transport
0.52	GO:0040007	growth
0.48	GO:0006896	Golgi to vacuole transport
0.35	GO:0015031	protein transport
0.32	GO:0008063	Toll signaling pathway

0.47	GO:0019905	syntaxin binding
0.32	GO:0003676	nucleic acid binding

0.68	GO:0005829	cytosol
0.59	GO:0000938	GARP complex
0.53	GO:0005802	trans-Golgi network
0.53	GO:0048471	perinuclear region of cytoplasm
0.48	GO:0005654	nucleoplasm
0.34	GO:0000139	Golgi membrane
0.30	GO:0016021	integral component of membrane

tr|T1G5G4|T1G5G4_HELRO
Uncharacterized protein
Search

UBE2H

0.63	Ubiquitin-conjugating enzyme h

0.48	GO:0070979	protein K11-linked ubiquitination
0.48	GO:0070936	protein K48-linked ubiquitination
0.46	GO:0006511	ubiquitin-dependent protein catabolic process
0.44	GO:0010498	proteasomal protein catabolic process

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0061631	ubiquitin conjugating enzyme activity
0.45	GO:0031625	ubiquitin protein ligase binding
0.44	GO:0061630	ubiquitin protein ligase activity
0.37	GO:0016874	ligase activity

0.36	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

0.37

GO:0016874

tr|T1G5G5|T1G5G5_HELRO
Uncharacterized protein
Search

RABL3

0.71	Small GTPase

0.35	GO:0006559	L-phenylalanine catabolic process
0.35	GO:0006570	tyrosine metabolic process
0.33	GO:0055114	oxidation-reduction process

0.66	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0004411	homogentisate 1,2-dioxygenase activity
0.35	GO:0004045	aminoacyl-tRNA hydrolase activity
0.35	GO:0042802	identical protein binding
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0008144	drug binding

0.30

GO:0016020

membrane

0.35	EC:1.13.11.5	GO:0004411
0.35	KEGG:R02519	GO:0004411

tr|T1G5G6|T1G5G6_HELRO
Uncharacterized protein
Search

0.81	Large subunit ribosomal protein L24

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.34	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.34	GO:0006754	ATP biosynthetic process
0.34	GO:0099132	ATP hydrolysis coupled cation transmembrane transport

0.64	GO:0003735	structural constituent of ribosome
0.34	GO:0005509	calcium ion binding
0.34	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism
0.33	GO:0019843	rRNA binding

0.61	GO:0005840	ribosome
0.39	GO:0005759	mitochondrial matrix
0.34	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)
0.30	GO:0016021	integral component of membrane

tr|T1G5G7|T1G5G7_HELRO
Uncharacterized protein
Search

tr|T1G5G8|T1G5G8_HELRO
Uncharacterized protein
Search

CHAT

0.95	Choline O-acetyltransferase a

0.48	GO:0060416	response to growth hormone
0.41	GO:0007626	locomotory behavior
0.41	GO:0008292	acetylcholine biosynthetic process
0.41	GO:0007274	neuromuscular synaptic transmission
0.36	GO:0007529	establishment of synaptic specificity at neuromuscular junction
0.36	GO:0043179	rhythmic excitation
0.35	GO:0007622	rhythmic behavior
0.35	GO:0007399	nervous system development
0.35	GO:0016358	dendrite development
0.35	GO:0030534	adult behavior

0.63

GO:0016746

transferase activity, transferring acyl groups

0.35	GO:0043025	neuronal cell body
0.35	GO:0043005	neuron projection
0.33	GO:0005829	cytosol
0.33	GO:0043227	membrane-bounded organelle
0.33	GO:0060076	excitatory synapse
0.33	GO:0043229	intracellular organelle
0.32	GO:0044422	organelle part
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.63

EC:2.3

GO:0016746

tr|T1G5G9|T1G5G9_HELRO
Uncharacterized protein
Search

0.46	GO:0021891	olfactory bulb interneuron development
0.45	GO:0035137	hindlimb morphogenesis
0.45	GO:0045879	negative regulation of smoothened signaling pathway
0.45	GO:0035136	forelimb morphogenesis
0.42	GO:0006366	transcription by RNA polymerase II
0.38	GO:0007165	signal transduction
0.37	GO:1903506	regulation of nucleic acid-templated transcription
0.37	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.37	GO:0010468	regulation of gene expression
0.35	GO:0035118	embryonic pectoral fin morphogenesis

0.51	GO:0003676	nucleic acid binding
0.39	GO:0008270	zinc ion binding
0.39	GO:0003700	DNA binding transcription factor activity
0.34	GO:0003682	chromatin binding
0.33	GO:0042802	identical protein binding
0.33	GO:0016831	carboxy-lyase activity
0.32	GO:0016787	hydrolase activity

0.42	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.33

EC:4.1.1

GO:0016831

tr|T1G5H0|T1G5H0_HELRO
Uncharacterized protein
Search

tr|T1G5H1|T1G5H1_HELRO
Uncharacterized protein
Search

0.58	GO:2000031	regulation of salicylic acid mediated signaling pathway
0.58	GO:0071446	cellular response to salicylic acid stimulus
0.51	GO:0070838	divalent metal ion transport
0.51	GO:0031347	regulation of defense response
0.46	GO:0034220	ion transmembrane transport
0.42	GO:1990126	retrograde transport, endosome to plasma membrane
0.41	GO:0000056	ribosomal small subunit export from nucleus
0.40	GO:0006970	response to osmotic stress
0.39	GO:0043065	positive regulation of apoptotic process
0.39	GO:0032880	regulation of protein localization

0.50	GO:0046873	metal ion transmembrane transporter activity
0.49	GO:0019706	protein-cysteine S-palmitoyltransferase activity
0.45	GO:0005216	ion channel activity
0.41	GO:0102567	phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
0.41	GO:0102568	phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
0.40	GO:0004623	phospholipase A2 activity
0.38	GO:0051082	unfolded protein binding
0.37	GO:0004674	protein serine/threonine kinase activity
0.37	GO:0003735	structural constituent of ribosome
0.37	GO:0020037	heme binding

0.41	GO:0031436	BRCA1-BARD1 complex
0.36	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.49

EC:2.3.1.225

GO:0019706

tr|T1G5H2|T1G5H2_HELRO
Uncharacterized protein
Search

0.47	GO:0007219	Notch signaling pathway
0.44	GO:0010466	negative regulation of peptidase activity
0.43	GO:0007275	multicellular organism development
0.43	GO:0071805	potassium ion transmembrane transport
0.42	GO:0015074	DNA integration
0.40	GO:0055114	oxidation-reduction process

0.49	GO:0003995	acyl-CoA dehydrogenase activity
0.45	GO:0050660	flavin adenine dinucleotide binding
0.45	GO:0032550	purine ribonucleoside binding
0.45	GO:0019001	guanyl nucleotide binding
0.44	GO:0030414	peptidase inhibitor activity
0.44	GO:0005267	potassium channel activity
0.40	GO:0032555	purine ribonucleotide binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0003677	DNA binding

0.41	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.49

EC:1.3.99.3

GO:0003995

tr|T1G5H3|T1G5H3_HELRO
Uncharacterized protein
Search

0.41	Synaptic vesicle-associated GTP-binding protein (Fragment)

0.42	GO:0043051	regulation of pharyngeal pumping
0.42	GO:0050804	modulation of chemical synaptic transmission
0.42	GO:1905488	positive regulation of anterior/posterior axon guidance
0.42	GO:0007271	synaptic transmission, cholinergic
0.42	GO:0018125	peptidyl-cysteine methylation
0.41	GO:0007419	ventral cord development
0.41	GO:0007617	mating behavior
0.39	GO:0051944	positive regulation of catecholamine uptake involved in synaptic transmission
0.39	GO:0017157	regulation of exocytosis
0.39	GO:0097494	regulation of vesicle size

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0031489	myosin V binding
0.41	GO:0030742	GTP-dependent protein binding
0.34	GO:0004767	sphingomyelin phosphodiesterase activity
0.34	GO:0005337	nucleoside transmembrane transporter activity
0.33	GO:0003677	DNA binding

0.45	GO:0099503	secretory vesicle
0.44	GO:0098793	presynapse
0.43	GO:0030133	transport vesicle
0.39	GO:0043005	neuron projection
0.37	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0005881	cytoplasmic microtubule
0.34	GO:0043231	intracellular membrane-bounded organelle
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.34	EC:3.1.4.12	GO:0004767
0.34	KEGG:R02541	GO:0004767

tr|T1G5H4|T1G5H4_HELRO
Uncharacterized protein
Search

MYO1E

0.51	Unconventional myosin-Ie

0.74	GO:0007018	microtubule-based movement
0.70	GO:0007605	sensory perception of sound
0.36	GO:0007165	signal transduction
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression
0.33	GO:0007015	actin filament organization
0.33	GO:0006364	rRNA processing
0.33	GO:0032259	methylation
0.32	GO:0015031	protein transport

0.74	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.74	GO:0003779	actin binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0032403	protein complex binding
0.36	GO:0008134	transcription factor binding
0.34	GO:0046872	metal ion binding
0.33	GO:0008168	methyltransferase activity

0.77	GO:0016459	myosin complex
0.33	GO:0005838	proteasome regulatory particle
0.33	GO:0005634	nucleus
0.32	GO:0005737	cytoplasm

0.33

GO:0008168

tr|T1G5H5|T1G5H5_HELRO
Signal recognition particle subunit SRP72
Search

SRP72

0.71	Signal recognition particle 72

0.75	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.48	GO:0042493	response to drug
0.43	GO:0065002	intracellular protein transmembrane transport

0.74	GO:0008312	7S RNA binding
0.57	GO:0030911	TPR domain binding
0.54	GO:0005047	signal recognition particle binding
0.49	GO:0043022	ribosome binding
0.35	GO:0032550	purine ribonucleoside binding
0.35	GO:0032561	guanyl ribonucleotide binding
0.35	GO:0042802	identical protein binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.73	GO:0048500	signal recognition particle
0.48	GO:0005783	endoplasmic reticulum
0.36	GO:0005730	nucleolus
0.35	GO:0005829	cytosol

tr|T1G5H6|T1G5H6_HELRO
Uncharacterized protein
Search

0.55	Histone lysine demethylase PHF8

0.59	GO:0032259	methylation
0.53	GO:0070076	histone lysine demethylation
0.46	GO:0007420	brain development
0.42	GO:0045893	positive regulation of transcription, DNA-templated
0.42	GO:0061187	regulation of chromatin silencing at rDNA
0.41	GO:0045815	positive regulation of gene expression, epigenetic
0.41	GO:0006356	regulation of transcription by RNA polymerase I
0.41	GO:1905268	negative regulation of chromatin organization
0.41	GO:0000082	G1/S transition of mitotic cell cycle
0.41	GO:0060969	negative regulation of gene silencing

0.59	GO:0008168	methyltransferase activity
0.53	GO:0032452	histone demethylase activity
0.52	GO:0046872	metal ion binding
0.48	GO:0016706	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
0.47	GO:0035064	methylated histone binding
0.39	GO:0003682	chromatin binding

0.59	GO:0005634	nucleus
0.41	GO:0031974	membrane-enclosed lumen
0.38	GO:0043232	intracellular non-membrane-bounded organelle
0.38	GO:0044446	intracellular organelle part
0.36	GO:0012505	endomembrane system
0.35	GO:0031090	organelle membrane
0.35	GO:0031975	envelope

0.59

GO:0008168

tr|T1G5H7|T1G5H7_HELRO
Single-stranded DNA-binding protein
Search

SSBP1

0.39	Mitochondrial DNA specific single-stranded DNA binding protein (Mt-SSB)

0.66	GO:0006260	DNA replication
0.57	GO:0051096	positive regulation of helicase activity
0.56	GO:0070584	mitochondrion morphogenesis
0.41	GO:0006310	DNA recombination
0.41	GO:0033554	cellular response to stress
0.35	GO:0006986	response to unfolded protein
0.34	GO:0050909	sensory perception of taste
0.34	GO:0006468	protein phosphorylation
0.34	GO:0045944	positive regulation of transcription by RNA polymerase II
0.34	GO:0071310	cellular response to organic substance

0.74	GO:0003697	single-stranded DNA binding
0.52	GO:0003682	chromatin binding
0.35	GO:0035497	cAMP response element binding
0.34	GO:0004672	protein kinase activity
0.34	GO:0004930	G-protein coupled receptor activity
0.34	GO:0003723	RNA binding
0.33	GO:0005524	ATP binding
0.33	GO:0005515	protein binding
0.33	GO:0003700	DNA binding transcription factor activity

0.54	GO:0042645	mitochondrial nucleoid
0.36	GO:0070062	extracellular exosome
0.34	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

tr|T1G5H8|T1G5H8_HELRO
Ribosomal protein
Search

0.53	Ribosomal protein L1

0.59	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.41	GO:0042273	ribosomal large subunit biogenesis
0.39	GO:0016072	rRNA metabolic process
0.36	GO:0045471	response to ethanol
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.33	GO:0019083	viral transcription

0.63	GO:0003735	structural constituent of ribosome
0.58	GO:0003723	RNA binding
0.34	GO:0004725	protein tyrosine phosphatase activity
0.33	GO:0005515	protein binding

0.70	GO:0015934	large ribosomal subunit
0.45	GO:0042788	polysomal ribosome
0.44	GO:0022626	cytosolic ribosome
0.35	GO:0005925	focal adhesion
0.35	GO:0070062	extracellular exosome
0.33	GO:0005634	nucleus
0.33	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0004725

tr|T1G5H9|T1G5H9_HELRO
Uncharacterized protein
Search

FAK

0.82	Focal adhesion kinase (Fragment)

0.78	GO:0007172	signal complex assembly
0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.55	GO:0007165	signal transduction
0.49	GO:0045886	negative regulation of synaptic growth at neuromuscular junction
0.48	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway
0.47	GO:0043407	negative regulation of MAP kinase activity
0.42	GO:0007016	cytoskeletal anchoring at plasma membrane
0.40	GO:0070309	lens fiber cell morphogenesis
0.38	GO:0046777	protein autophosphorylation
0.38	GO:0045087	innate immune response

0.77	GO:0004713	protein tyrosine kinase activity
0.58	GO:0004871	signal transducer activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0005102	receptor binding
0.33	GO:0099600	transmembrane receptor activity

0.73	GO:0005925	focal adhesion
0.66	GO:0005856	cytoskeleton
0.50	GO:0061177	type Is terminal bouton
0.50	GO:0061176	type Ib terminal bouton
0.38	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.30	GO:0016021	integral component of membrane

0.77

GO:0004713

tr|T1G5I0|T1G5I0_HELRO
Uncharacterized protein
Search

0.74	GO:0007018	microtubule-based movement
0.42	GO:0022402	cell cycle process
0.42	GO:0044837	actomyosin contractile ring organization
0.41	GO:0099518	vesicle cytoskeletal trafficking
0.40	GO:0051301	cell division
0.38	GO:0022607	cellular component assembly
0.36	GO:0000280	nuclear division
0.36	GO:0000226	microtubule cytoskeleton organization
0.36	GO:0000278	mitotic cell cycle
0.36	GO:0007059	chromosome segregation

0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0016887	ATPase activity
0.33	GO:0004871	signal transducer activity
0.32	GO:0016491	oxidoreductase activity

0.65	GO:0005874	microtubule
0.43	GO:0005871	kinesin complex
0.38	GO:0005794	Golgi apparatus
0.35	GO:0030896	checkpoint clamp complex
0.35	GO:1905360	GTPase complex
0.35	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.34	GO:0098797	plasma membrane protein complex
0.30	GO:0031224	intrinsic component of membrane

0.39

GO:0016887

tr|T1G5I1|T1G5I1_HELRO
Uncharacterized protein
Search

0.44	Putative seven transmembrane receptor

0.45	GO:0008039	synaptic target recognition
0.43	GO:0050832	defense response to fungus

0.36	GO:0005215	transporter activity
0.34	GO:0030246	carbohydrate binding
0.32	GO:0046872	metal ion binding
0.30	GO:0003824	catalytic activity

0.30

GO:0031224

intrinsic component of membrane

tr|T1G5I2|T1G5I2_HELRO
Uncharacterized protein
Search

KCND3

0.85	Potassium voltage-gated channel protein Shal

0.78	GO:0051260	protein homooligomerization
0.78	GO:0034765	regulation of ion transmembrane transport
0.73	GO:0071805	potassium ion transmembrane transport
0.57	GO:0098915	membrane repolarization during ventricular cardiac muscle cell action potential
0.55	GO:0035637	multicellular organismal signaling
0.54	GO:0002027	regulation of heart rate
0.53	GO:0140115	export across plasma membrane
0.40	GO:0007610	behavior
0.40	GO:0019233	sensory perception of pain
0.39	GO:0007623	circadian rhythm

0.78	GO:0005249	voltage-gated potassium channel activity
0.54	GO:0044325	ion channel binding
0.36	GO:1905030	voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential
0.35	GO:0046872	metal ion binding
0.34	GO:0046982	protein heterodimerization activity

0.78	GO:0008076	voltage-gated potassium channel complex
0.41	GO:0030425	dendrite
0.40	GO:0042383	sarcolemma
0.39	GO:0043025	neuronal cell body
0.39	GO:0044309	neuron spine
0.39	GO:0098590	plasma membrane region
0.38	GO:0098794	postsynapse
0.38	GO:0044298	cell body membrane
0.38	GO:0045121	membrane raft
0.36	GO:0097038	perinuclear endoplasmic reticulum

tr|T1G5I3|T1G5I3_HELRO
Uncharacterized protein
Search

tr|T1G5I4|T1G5I4_HELRO
Uncharacterized protein
Search

DDC

0.58	Aromatic-L-amino-acid decarboxylase

0.60	GO:0006520	cellular amino acid metabolic process
0.40	GO:0042416	dopamine biosynthetic process
0.40	GO:0009636	response to toxic substance
0.39	GO:0033076	isoquinoline alkaloid metabolic process
0.38	GO:0015842	aminergic neurotransmitter loading into synaptic vesicle
0.38	GO:0052314	phytoalexin metabolic process
0.38	GO:0042427	serotonin biosynthetic process
0.38	GO:0007275	multicellular organism development
0.38	GO:0071312	cellular response to alkaloid
0.37	GO:0060322	head development

0.68	GO:0016831	carboxy-lyase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.41	GO:0019899	enzyme binding
0.36	GO:0019904	protein domain specific binding
0.36	GO:0016597	amino acid binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.38	GO:0043025	neuronal cell body
0.38	GO:0030424	axon
0.37	GO:0008021	synaptic vesicle
0.34	GO:0070062	extracellular exosome

0.68

EC:4.1.1

GO:0016831

tr|T1G5I5|T1G5I5_HELRO
Uncharacterized protein
Search

0.72	Putative microtubule-binding protein involved in cell cycle control

0.64	GO:0070507	regulation of microtubule cytoskeleton organization
0.41	GO:0009792	embryo development ending in birth or egg hatching
0.40	GO:0048513	animal organ development
0.39	GO:1904888	cranial skeletal system development
0.39	GO:1903031	regulation of microtubule plus-end binding
0.39	GO:1904528	positive regulation of microtubule binding
0.39	GO:0001501	skeletal system development
0.39	GO:0030588	pseudocleavage
0.39	GO:0007629	flight behavior
0.38	GO:0048598	embryonic morphogenesis

0.74	GO:0008017	microtubule binding
0.39	GO:0042802	identical protein binding
0.39	GO:0008022	protein C-terminus binding
0.38	GO:0019901	protein kinase binding
0.38	GO:0017022	myosin binding
0.34	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds

0.72	GO:0005874	microtubule
0.38	GO:0030496	midbody
0.37	GO:0044295	axonal growth cone
0.37	GO:0005819	spindle
0.34	GO:0005737	cytoplasm
0.34	GO:0005875	microtubule associated complex
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.34

EC:3.5

GO:0016810

tr|T1G5I6|T1G5I6_HELRO
Uncharacterized protein
Search

0.73	GO:0010923	negative regulation of phosphatase activity
0.47	GO:0007018	microtubule-based movement
0.43	GO:0007165	signal transduction
0.39	GO:0051902	negative regulation of mitochondrial depolarization
0.39	GO:0002903	negative regulation of B cell apoptotic process
0.38	GO:0046580	negative regulation of Ras protein signal transduction
0.38	GO:0042110	T cell activation
0.37	GO:0043547	positive regulation of GTPase activity
0.37	GO:0009967	positive regulation of signal transduction

0.74	GO:0019902	phosphatase binding
0.47	GO:0003777	microtubule motor activity
0.47	GO:0008017	microtubule binding
0.47	GO:0003779	actin binding
0.40	GO:0032559	adenyl ribonucleotide binding
0.39	GO:0008144	drug binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0005070	SH3/SH2 adaptor activity
0.37	GO:0005096	GTPase activator activity

0.62	GO:0005829	cytosol
0.48	GO:0016459	myosin complex
0.36	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane
0.35	GO:0005739	mitochondrion

tr|T1G5I7|T1G5I7_HELRO
Uncharacterized protein
Search

0.86	Dopamine receptor, invertebrate (Fragment)

0.78	GO:0071875	adrenergic receptor signaling pathway
0.75	GO:0006940	regulation of smooth muscle contraction
0.75	GO:0019229	regulation of vasoconstriction
0.74	GO:0030168	platelet activation
0.54	GO:0035625	epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway
0.52	GO:0032148	activation of protein kinase B activity
0.50	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.50	GO:0045666	positive regulation of neuron differentiation
0.49	GO:0043410	positive regulation of MAPK cascade
0.44	GO:0007208	phospholipase C-activating serotonin receptor signaling pathway

0.78	GO:0004935	adrenergic receptor activity
0.54	GO:0051379	epinephrine binding
0.42	GO:0099589	serotonin receptor activity
0.42	GO:0030594	neurotransmitter receptor activity
0.42	GO:0004977	melanocortin receptor activity
0.41	GO:0031694	alpha-2A adrenergic receptor binding
0.38	GO:0042803	protein homodimerization activity
0.38	GO:0046982	protein heterodimerization activity
0.33	GO:0004222	metalloendopeptidase activity
0.33	GO:0008270	zinc ion binding

0.52	GO:0005886	plasma membrane
0.35	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

0.33

GO:0004222

tr|T1G5I8|T1G5I8_HELRO
Uncharacterized protein
Search

tr|T1G5I9|T1G5I9_HELRO
Uncharacterized protein
Search

PIP4K2A

0.83	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

0.75	GO:0046854	phosphatidylinositol phosphorylation
0.55	GO:2000786	positive regulation of autophagosome assembly
0.55	GO:0035855	megakaryocyte development
0.46	GO:1900186	negative regulation of clathrin-dependent endocytosis
0.44	GO:0040018	positive regulation of multicellular organism growth
0.43	GO:0030307	positive regulation of cell growth
0.42	GO:0032006	regulation of TOR signaling
0.38	GO:0048634	regulation of muscle organ development
0.35	GO:0014066	regulation of phosphatidylinositol 3-kinase signaling
0.34	GO:0006661	phosphatidylinositol biosynthetic process

0.82	GO:0016307	phosphatidylinositol phosphate kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding
0.33	GO:0003777	microtubule motor activity

0.53	GO:0005776	autophagosome
0.42	GO:0005769	early endosome
0.38	GO:0005886	plasma membrane
0.36	GO:0005634	nucleus
0.33	GO:0005829	cytosol
0.33	GO:0043233	organelle lumen
0.32	GO:0044446	intracellular organelle part

0.82

GO:0016307

tr|T1G5J0|T1G5J0_HELRO
Uncharacterized protein
Search

0.73	GO:0006814	sodium ion transport
0.55	GO:0055085	transmembrane transport
0.39	GO:0015746	citrate transport
0.37	GO:0008272	sulfate transport

0.56	GO:0005215	transporter activity
0.34	GO:0051540	metal cluster binding
0.33	GO:0048037	cofactor binding
0.30	GO:0003824	catalytic activity

0.30

GO:0044425

membrane part

tr|T1G5J1|T1G5J1_HELRO
Uncharacterized protein
Search

tr|T1G5J2|T1G5J2_HELRO
Uncharacterized protein
Search

0.80	Nicotinic acetylcholine receptor subunit type E

0.79	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.35	GO:0017085	response to insecticide
0.35	GO:0007271	synaptic transmission, cholinergic
0.33	GO:0006812	cation transport

0.82	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0099600	transmembrane receptor activity

0.78	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.35	GO:0005892	acetylcholine-gated channel complex

tr|T1G5J3|T1G5J3_HELRO
Uncharacterized protein
Search

0.17	PAS domain containing serine/threonine kinase

0.63	GO:0006468	protein phosphorylation
0.50	GO:0000281	mitotic cytokinesis
0.43	GO:0035556	intracellular signal transduction
0.42	GO:0051402	neuron apoptotic process
0.42	GO:0032467	positive regulation of cytokinesis
0.41	GO:0043066	negative regulation of apoptotic process
0.40	GO:0045719	negative regulation of glycogen biosynthetic process
0.38	GO:0070092	regulation of glucagon secretion
0.37	GO:2000505	regulation of energy homeostasis
0.37	GO:0043576	regulation of respiratory gaseous exchange

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0097110	scaffold protein binding
0.42	GO:0030165	PDZ domain binding
0.39	GO:0046872	metal ion binding
0.36	GO:0035091	phosphatidylinositol binding
0.35	GO:0017048	Rho GTPase binding
0.35	GO:0004383	guanylate cyclase activity

0.36	GO:0005622	intracellular
0.36	GO:0097610	cell surface furrow
0.35	GO:0030496	midbody
0.35	GO:0032155	cell division site part
0.35	GO:0043025	neuronal cell body
0.35	GO:0043227	membrane-bounded organelle
0.34	GO:0001726	ruffle
0.34	GO:0012505	endomembrane system
0.33	GO:0044422	organelle part
0.33	GO:0005886	plasma membrane

0.35

GO:0004383

tr|T1G5J4|T1G5J4_HELRO
Uncharacterized protein
Search

0.53	GO:0030509	BMP signaling pathway
0.52	GO:0060828	regulation of canonical Wnt signaling pathway
0.50	GO:0048513	animal organ development
0.43	GO:1901631	positive regulation of presynaptic membrane organization
0.43	GO:0003002	regionalization
0.43	GO:1904395	positive regulation of skeletal muscle acetylcholine-gated channel clustering
0.43	GO:0051239	regulation of multicellular organismal process
0.42	GO:0071340	skeletal muscle acetylcholine-gated channel clustering
0.42	GO:0097105	presynaptic membrane assembly
0.42	GO:0097104	postsynaptic membrane assembly

0.65	GO:0005509	calcium ion binding
0.41	GO:0004252	serine-type endopeptidase activity
0.41	GO:0030971	receptor tyrosine kinase binding
0.40	GO:0017147	Wnt-protein binding
0.40	GO:0042813	Wnt-activated receptor activity
0.39	GO:0042803	protein homodimerization activity
0.38	GO:0038024	cargo receptor activity
0.37	GO:0034185	apolipoprotein binding
0.36	GO:0071936	coreceptor activity involved in Wnt signaling pathway
0.35	GO:0035258	steroid hormone receptor binding

0.42	GO:0009986	cell surface
0.41	GO:0031594	neuromuscular junction
0.41	GO:0043235	receptor complex
0.39	GO:0098590	plasma membrane region
0.38	GO:0036477	somatodendritic compartment
0.38	GO:0098589	membrane region
0.38	GO:0005794	Golgi apparatus
0.38	GO:0005903	brush border
0.38	GO:0005768	endosome
0.38	GO:0043005	neuron projection

0.41

GO:0004252

tr|T1G5J5|T1G5J5_HELRO
Tyrosine-protein kinase
Search

0.57	Tyrosine-protein kinase Yes

0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.54	GO:0046777	protein autophosphorylation
0.52	GO:0042327	positive regulation of phosphorylation
0.51	GO:0071300	cellular response to retinoic acid
0.51	GO:0043304	regulation of mast cell degranulation
0.50	GO:1903727	positive regulation of phospholipid metabolic process
0.50	GO:0001932	regulation of protein phosphorylation
0.50	GO:0043551	regulation of phosphatidylinositol 3-kinase activity
0.49	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.49	GO:0051272	positive regulation of cellular component movement

0.80	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.54	GO:0001784	phosphotyrosine residue binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0044325	ion channel binding
0.50	GO:0005102	receptor binding
0.48	GO:0019899	enzyme binding
0.46	GO:0032403	protein complex binding

0.48	GO:0015629	actin cytoskeleton
0.47	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.47	GO:0005794	Golgi apparatus
0.46	GO:0016235	aggresome
0.46	GO:0032587	ruffle membrane
0.43	GO:0005829	cytosol
0.42	GO:0099513	polymeric cytoskeletal fiber
0.42	GO:0045121	membrane raft
0.42	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0005634	nucleus

0.80

GO:0004715

tr|T1G5J6|T1G5J6_HELRO
Uncharacterized protein
Search

COX19

0.62	Copper metallochaperone, required for cytochrome c oxidase assembly, putative

0.74	GO:0033617	mitochondrial respiratory chain complex IV assembly
0.56	GO:0030001	metal ion transport
0.51	GO:0006878	cellular copper ion homeostasis
0.44	GO:0009060	aerobic respiration
0.36	GO:0043547	positive regulation of GTPase activity

0.60	GO:0005507	copper ion binding
0.39	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.37	GO:1902936	phosphatidylinositol bisphosphate binding
0.37	GO:0004633	phosphopantothenoylcysteine decarboxylase activity
0.36	GO:0005096	GTPase activator activity
0.35	GO:0005515	protein binding
0.33	GO:0003676	nucleic acid binding

0.74	GO:0005758	mitochondrial intermembrane space
0.62	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.39	EC:1.6.5.3	GO:0008137
0.37	KEGG:R03269	GO:0004633

tr|T1G5J7|T1G5J7_HELRO
Uncharacterized protein
Search

0.71	GO:0007166	cell surface receptor signaling pathway
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.51	GO:0019933	cAMP-mediated signaling
0.47	GO:0060347	heart trabecula formation
0.46	GO:0022011	myelination in peripheral nervous system
0.43	GO:0007005	mitochondrion organization
0.32	GO:0006898	receptor-mediated endocytosis
0.32	GO:0045454	cell redox homeostasis

0.72	GO:0004930	G-protein coupled receptor activity
0.46	GO:0030246	carbohydrate binding
0.46	GO:0043236	laminin binding
0.35	GO:0005518	collagen binding
0.33	GO:0005044	scavenger receptor activity
0.32	GO:0005509	calcium ion binding

0.40	GO:0005886	plasma membrane
0.36	GO:0005622	intracellular
0.33	GO:0009986	cell surface
0.30	GO:0016021	integral component of membrane

tr|T1G5J8|T1G5J8_HELRO
Uncharacterized protein
Search

ARMC4

0.96	Armadillo repeat-containing protein 4

0.72	GO:0003356	regulation of cilium beat frequency
0.71	GO:0036158	outer dynein arm assembly
0.70	GO:0007368	determination of left/right symmetry
0.69	GO:0021591	ventricular system development
0.68	GO:0003341	cilium movement
0.66	GO:0007507	heart development
0.34	GO:0006351	transcription, DNA-templated
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:0010468	regulation of gene expression

0.34	GO:0003700	DNA binding transcription factor activity
0.33	GO:0003677	DNA binding

0.70	GO:0097546	ciliary base
0.66	GO:0005930	axoneme
0.46	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

tr|T1G5J9|T1G5J9_HELRO
Uncharacterized protein
Search

0.61	GO:0007165	signal transduction
0.54	GO:0045087	innate immune response
0.42	GO:0002218	activation of innate immune response
0.41	GO:0043408	regulation of MAPK cascade
0.41	GO:0009615	response to virus

0.40	GO:0042803	protein homodimerization activity
0.38	GO:0019843	rRNA binding

0.40	GO:0005768	endosome
0.30	GO:0016020	membrane

tr|T1G5K0|T1G5K0_HELRO
Uncharacterized protein
Search

0.56	Aromatic-L-amino acid decarboxylase

0.60	GO:0006520	cellular amino acid metabolic process
0.46	GO:0048148	behavioral response to cocaine
0.46	GO:0018991	oviposition
0.45	GO:0045475	locomotor rhythm
0.38	GO:0001694	histamine biosynthetic process
0.36	GO:0052805	imidazole-containing compound catabolic process
0.35	GO:0046395	carboxylic acid catabolic process
0.35	GO:0006589	octopamine biosynthetic process
0.35	GO:0009636	response to toxic substance

0.68	GO:0016831	carboxy-lyase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.35	GO:0019899	enzyme binding
0.33	GO:0016874	ligase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.34	GO:0043025	neuronal cell body
0.34	GO:0030424	axon
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.68

EC:4.1.1

GO:0016831

tr|T1G5K1|T1G5K1_HELRO
Uncharacterized protein
Search

GK5

0.84	Putative glycerol kinase 5

0.67	GO:0019563	glycerol catabolic process
0.66	GO:0006072	glycerol-3-phosphate metabolic process
0.57	GO:0016310	phosphorylation
0.40	GO:0006641	triglyceride metabolic process
0.36	GO:1901137	carbohydrate derivative biosynthetic process
0.36	GO:0090407	organophosphate biosynthetic process

0.69	GO:0004370	glycerol kinase activity
0.49	GO:0030554	adenyl nucleotide binding
0.48	GO:0097367	carbohydrate derivative binding
0.48	GO:0008144	drug binding
0.48	GO:0035639	purine ribonucleoside triphosphate binding

0.36	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.69	EC:2.7.1.30	GO:0004370
0.69	KEGG:R00847	GO:0004370

tr|T1G5K2|T1G5K2_HELRO
Uncharacterized protein
Search

0.43	GO:0046907	intracellular transport
0.41	GO:0034613	cellular protein localization
0.40	GO:0015031	protein transport
0.38	GO:0051647	nucleus localization
0.38	GO:2000574	regulation of microtubule motor activity
0.38	GO:0000132	establishment of mitotic spindle orientation
0.38	GO:0031023	microtubule organizing center organization
0.38	GO:0099111	microtubule-based transport
0.38	GO:0051650	establishment of vesicle localization
0.38	GO:0007281	germ cell development

0.54	GO:0003723	RNA binding
0.43	GO:0032559	adenyl ribonucleotide binding
0.42	GO:0008144	drug binding
0.42	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0070840	dynein complex binding
0.37	GO:0008017	microtubule binding
0.36	GO:0008289	lipid binding

0.39	GO:1904115	axon cytoplasm
0.37	GO:0000776	kinetochore
0.37	GO:0005813	centrosome
0.37	GO:0005875	microtubule associated complex
0.37	GO:0005938	cell cortex
0.37	GO:0005874	microtubule
0.36	GO:0005634	nucleus
0.36	GO:0005576	extracellular region
0.35	GO:0030529	intracellular ribonucleoprotein complex
0.35	GO:0005886	plasma membrane

tr|T1G5K3|T1G5K3_HELRO
Uncharacterized protein
Search

0.65

GO:0016567

protein ubiquitination

0.66	GO:0004842	ubiquitin-protein transferase activity
0.50	GO:0046872	metal ion binding

0.66

GO:0004842

tr|T1G5K4|T1G5K4_HELRO
Transcription elongation factor 1 homolog
Search

ELOF1

0.71	Transcription elongation factor 1 homolog

0.57	GO:0006351	transcription, DNA-templated
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0006414	translational elongation
0.56	GO:0010468	regulation of gene expression
0.45	GO:0006338	chromatin remodeling
0.43	GO:1902680	positive regulation of RNA biosynthetic process

0.57	GO:0003746	translation elongation factor activity
0.53	GO:0046872	metal ion binding
0.47	GO:0000993	RNA polymerase II core binding

0.61	GO:0005634	nucleus
0.42	GO:0031974	membrane-enclosed lumen
0.39	GO:0043234	protein complex
0.39	GO:0044446	intracellular organelle part

tr|T1G5K5|T1G5K5_HELRO
Uncharacterized protein
Search

tr|T1G5K6|T1G5K6_HELRO
Uncharacterized protein
Search

0.63	Signal peptide, CUB domain and EGF like domain containing 3

0.42	GO:0045880	positive regulation of smoothened signaling pathway
0.42	GO:0032502	developmental process
0.40	GO:0051260	protein homooligomerization
0.38	GO:0007154	cell communication
0.38	GO:0023052	signaling
0.38	GO:0051716	cellular response to stimulus
0.37	GO:0035583	sequestering of TGFbeta in extracellular matrix
0.37	GO:0051291	protein heterooligomerization
0.36	GO:0032501	multicellular organismal process
0.36	GO:0030501	positive regulation of bone mineralization

0.70	GO:0005509	calcium ion binding
0.42	GO:0005201	extracellular matrix structural constituent
0.38	GO:0046982	protein heterodimerization activity
0.38	GO:0042802	identical protein binding
0.35	GO:0005044	scavenger receptor activity
0.33	GO:0019864	IgG binding
0.33	GO:0008061	chitin binding
0.33	GO:0004888	transmembrane signaling receptor activity
0.32	GO:0017056	structural constituent of nuclear pore
0.32	GO:0030247	polysaccharide binding

0.45	GO:0044421	extracellular region part
0.43	GO:0009986	cell surface
0.38	GO:0019897	extrinsic component of plasma membrane
0.38	GO:0098552	side of membrane
0.35	GO:0099512	supramolecular fiber
0.34	GO:0016324	apical plasma membrane
0.33	GO:0060170	ciliary membrane
0.33	GO:0005737	cytoplasm
0.33	GO:0016323	basolateral plasma membrane
0.33	GO:0031225	anchored component of membrane

tr|T1G5K7|T1G5K7_HELRO
Uncharacterized protein
Search

tr|T1G5K8|T1G5K8_HELRO
Uncharacterized protein
Search

FDX1

0.67	Adrenodoxin, mitochondrial

0.61	GO:0022900	electron transport chain
0.45	GO:1904321	response to forskolin
0.45	GO:0071320	cellular response to cAMP
0.44	GO:0008203	cholesterol metabolic process
0.44	GO:1901655	cellular response to ketone
0.43	GO:0035690	cellular response to drug
0.43	GO:0042446	hormone biosynthetic process
0.42	GO:0071396	cellular response to lipid
0.41	GO:1904087	negative regulation of epiboly involved in gastrulation with mouth forming second
0.39	GO:0046160	heme a metabolic process

0.71	GO:0051537	2 iron, 2 sulfur cluster binding
0.62	GO:0009055	electron transfer activity
0.39	GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor
0.34	GO:0008022	protein C-terminus binding
0.34	GO:0042803	protein homodimerization activity
0.33	GO:0046872	metal ion binding

0.40	GO:0005739	mitochondrion
0.37	GO:0031974	membrane-enclosed lumen
0.36	GO:0044446	intracellular organelle part

0.39

EC:1.6.2

GO:0016653

tr|T1G5K9|T1G5K9_HELRO
Uncharacterized protein
Search

0.80	Ezrin-moesin-radixin

0.38

GO:0008285

negative regulation of cell proliferation

0.71

GO:0008092

cytoskeletal protein binding

0.69	GO:0005856	cytoskeleton
0.30	GO:0044425	membrane part

tr|T1G5L0|T1G5L0_HELRO
Uncharacterized protein
Search

0.66	Cell division control protein 42

0.77	GO:0007264	small GTPase mediated signal transduction
0.46	GO:0007394	dorsal closure, elongation of leading edge cells
0.45	GO:0035099	hemocyte migration
0.45	GO:0001737	establishment of imaginal disc-derived wing hair orientation
0.45	GO:0007390	germ-band shortening
0.45	GO:0008258	head involution
0.44	GO:0042067	establishment of ommatidial planar polarity
0.44	GO:0030032	lamellipodium assembly
0.44	GO:0090303	positive regulation of wound healing
0.44	GO:0007254	JNK cascade

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.37	GO:0004767	sphingomyelin phosphodiesterase activity
0.33	GO:0005515	protein binding

0.45	GO:0005622	intracellular
0.35	GO:0043025	neuronal cell body
0.35	GO:0009898	cytoplasmic side of plasma membrane
0.34	GO:0031982	vesicle
0.30	GO:0016021	integral component of membrane

0.37	EC:3.1.4.12	GO:0004767
0.37	KEGG:R02541	GO:0004767

tr|T1G5L1|T1G5L1_HELRO
Uncharacterized protein
Search

tr|T1G5L2|T1G5L2_HELRO
Uncharacterized protein
Search

0.75	GO:0010923	negative regulation of phosphatase activity
0.41	GO:0016310	phosphorylation
0.37	GO:0006259	DNA metabolic process

0.76	GO:0019902	phosphatase binding
0.42	GO:0004531	deoxyribonuclease II activity
0.42	GO:0016301	kinase activity

0.64

GO:0005829

cytosol

0.42

EC:3.1.22.1

GO:0004531

tr|T1G5L3|T1G5L3_HELRO
Uncharacterized protein
Search

SLC13A2

0.52	Sodium-dependent dicarboxylate transporter

0.73	GO:0006814	sodium ion transport
0.55	GO:0055085	transmembrane transport
0.41	GO:0006820	anion transport
0.38	GO:0015849	organic acid transport
0.37	GO:0015893	drug transport
0.32	GO:0007165	signal transduction
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.56

GO:0005215

transporter activity

0.40	GO:0005887	integral component of plasma membrane
0.36	GO:0070062	extracellular exosome
0.32	GO:0005634	nucleus

tr|T1G5L4|T1G5L4_HELRO
Uncharacterized protein
Search

0.34

GO:0006955

immune response

0.64	GO:0003735	structural constituent of ribosome
0.35	GO:0005164	tumor necrosis factor receptor binding
0.34	GO:0019904	protein domain specific binding

0.82	GO:0005763	mitochondrial small ribosomal subunit
0.34	GO:0005730	nucleolus
0.30	GO:0031224	intrinsic component of membrane

tr|T1G5L5|T1G5L5_HELRO
Uncharacterized protein
Search

0.79	Stromal cell-derived factor 2

0.45	GO:0071712	ER-associated misfolded protein catabolic process
0.44	GO:0035269	protein O-linked mannosylation
0.34	GO:0006413	translational initiation
0.34	GO:0045087	innate immune response
0.34	GO:0002181	cytoplasmic translation
0.33	GO:0022618	ribonucleoprotein complex assembly

0.45	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity
0.34	GO:0003743	translation initiation factor activity

0.42	GO:0044432	endoplasmic reticulum part
0.41	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.40	GO:0031984	organelle subcompartment
0.35	GO:0005852	eukaryotic translation initiation factor 3 complex
0.34	GO:0016282	eukaryotic 43S preinitiation complex
0.34	GO:0033290	eukaryotic 48S preinitiation complex
0.30	GO:0031224	intrinsic component of membrane

0.45

EC:2.4.1.109

GO:0004169

tr|T1G5L6|T1G5L6_HELRO
Uncharacterized protein
Search

0.71	Gamma-aminobutyric acid receptor subunit gamma-1

0.61	GO:0007214	gamma-aminobutyric acid signaling pathway
0.60	GO:0034220	ion transmembrane transport
0.56	GO:0006821	chloride transport
0.39	GO:0007268	chemical synaptic transmission
0.39	GO:0071420	cellular response to histamine
0.37	GO:0030534	adult behavior
0.37	GO:0009791	post-embryonic development
0.36	GO:0060078	regulation of postsynaptic membrane potential
0.36	GO:1905114	cell surface receptor signaling pathway involved in cell-cell signaling
0.35	GO:0043200	response to amino acid

0.75	GO:0005230	extracellular ligand-gated ion channel activity
0.70	GO:0004888	transmembrane signaling receptor activity
0.39	GO:0005254	chloride channel activity
0.37	GO:0099095	ligand-gated anion channel activity
0.35	GO:0016594	glycine binding
0.33	GO:0044877	macromolecular complex binding
0.33	GO:0004674	protein serine/threonine kinase activity
0.33	GO:0070001	aspartic-type peptidase activity
0.32	GO:0004175	endopeptidase activity
0.32	GO:0140110	transcription regulator activity

0.55	GO:0005886	plasma membrane
0.39	GO:1902711	GABA-A receptor complex
0.37	GO:0030424	axon
0.37	GO:0098794	postsynapse
0.34	GO:0060077	inhibitory synapse
0.34	GO:0034707	chloride channel complex
0.33	GO:0030425	dendrite
0.33	GO:0031252	cell leading edge
0.33	GO:0030659	cytoplasmic vesicle membrane
0.33	GO:0030054	cell junction

0.33

GO:0004674

tr|T1G5L7|T1G5L7_HELRO
Hexosyltransferase
Search

0.44	Beta-1,3-galactosyltransferase brn

0.88	GO:0042248	maintenance of polarity of follicular epithelium
0.88	GO:0001744	optic lobe placode formation
0.88	GO:0007299	ovarian follicle cell-cell adhesion
0.86	GO:0006688	glycosphingolipid biosynthetic process
0.85	GO:0007293	germarium-derived egg chamber formation
0.85	GO:0007298	border follicle cell migration
0.82	GO:0007219	Notch signaling pathway
0.74	GO:0043413	macromolecule glycosylation
0.74	GO:0009101	glycoprotein biosynthetic process
0.70	GO:0007275	multicellular organism development

0.89	GO:0047915	ganglioside galactosyltransferase activity
0.89	GO:0046981	beta-1,4-mannosylglycolipid beta-1,3-N-acetylglucosaminyltransferase activity

0.79	GO:0005795	Golgi stack
0.74	GO:0000139	Golgi membrane
0.66	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.89

EC:2.4.1.62

GO:0047915

tr|T1G5L8|T1G5L8_HELRO
Uncharacterized protein
Search

0.56	Eukaryotic translation initiation factor x-chromosomal

0.72	GO:0006413	translational initiation
0.44	GO:0007224	smoothened signaling pathway

0.73	GO:0003743	translation initiation factor activity
0.54	GO:0033592	RNA strand annealing activity
0.35	GO:0003735	structural constituent of ribosome

0.37	GO:0005763	mitochondrial small ribosomal subunit
0.35	GO:0016282	eukaryotic 43S preinitiation complex
0.34	GO:0005654	nucleoplasm
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

tr|T1G5L9|T1G5L9_HELRO
Uncharacterized protein
Search

0.65	Putative syntaxin-binding protein 2 (Fragment)

0.36	GO:0006904	vesicle docking involved in exocytosis
0.35	GO:0033198	response to ATP
0.34	GO:0035590	purinergic nucleotide receptor signaling pathway
0.34	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.34	GO:0060079	excitatory postsynaptic potential
0.34	GO:0051209	release of sequestered calcium ion into cytosol
0.33	GO:0048015	phosphatidylinositol-mediated signaling
0.33	GO:0046854	phosphatidylinositol phosphorylation
0.33	GO:0007264	small GTPase mediated signal transduction
0.33	GO:0042981	regulation of apoptotic process

0.35	GO:0140135	mechanosensitive cation channel activity
0.35	GO:0015276	ligand-gated ion channel activity
0.35	GO:0035381	ATP-gated ion channel activity
0.34	GO:0016502	nucleotide receptor activity
0.34	GO:0035586	purinergic receptor activity
0.34	GO:0038062	protein tyrosine kinase collagen receptor activity
0.34	GO:0005262	calcium channel activity
0.34	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.33	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.33	GO:0033608	formyl-CoA transferase activity

0.34	GO:0005887	integral component of plasma membrane
0.34	GO:0098794	postsynapse
0.33	GO:0005739	mitochondrion

0.34	EC:1.6.5.3	GO:0008137
0.33	KEGG:R07290	GO:0033608

tr|T1G5M0|T1G5M0_HELRO
Uncharacterized protein
Search

tr|T1G5M1|T1G5M1_HELRO
Uncharacterized protein
Search

0.63	GO:0006468	protein phosphorylation
0.47	GO:1903288	positive regulation of potassium ion import
0.44	GO:0007411	axon guidance
0.44	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.43	GO:0035220	wing disc development
0.37	GO:0036251	positive regulation of transcription from RNA polymerase II promoter in response to salt stress
0.37	GO:0071475	cellular hyperosmotic salinity response
0.36	GO:0035556	intracellular signal transduction
0.36	GO:0050891	multicellular organismal water homeostasis
0.35	GO:0000122	negative regulation of transcription by RNA polymerase II

0.69	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005057	signal transducer activity, downstream of receptor
0.33	GO:0005515	protein binding

0.37	GO:0005829	cytosol
0.34	GO:0070603	SWI/SNF superfamily-type complex
0.30	GO:0016020	membrane

0.69

GO:0004674

tr|T1G5M2|T1G5M2_HELRO
Uncharacterized protein
Search

CUL3

0.81	Cullin-3-B

0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.55	GO:0044346	fibroblast apoptotic process
0.55	GO:0040016	embryonic cleavage
0.54	GO:0043149	stress fiber assembly
0.54	GO:0072576	liver morphogenesis
0.53	GO:0035024	negative regulation of Rho protein signal transduction
0.53	GO:0017145	stem cell division
0.53	GO:0045842	positive regulation of mitotic metaphase/anaphase transition
0.52	GO:0001831	trophectodermal cellular morphogenesis
0.52	GO:0007080	mitotic metaphase plate congression

0.79	GO:0031625	ubiquitin protein ligase binding
0.54	GO:0031208	POZ domain binding
0.52	GO:0005112	Notch binding
0.50	GO:0030332	cyclin binding
0.48	GO:0004842	ubiquitin-protein transferase activity
0.47	GO:0042803	protein homodimerization activity
0.47	GO:0046982	protein heterodimerization activity
0.44	GO:0061659	ubiquitin-like protein ligase activity

0.75	GO:0031461	cullin-RING ubiquitin ligase complex
0.54	GO:0005827	polar microtubule
0.48	GO:0000139	Golgi membrane
0.43	GO:0005634	nucleus
0.36	GO:0070062	extracellular exosome
0.33	GO:0005829	cytosol
0.33	GO:0070013	intracellular organelle lumen
0.30	GO:0016021	integral component of membrane

0.48

GO:0004842

tr|T1G5M3|T1G5M3_HELRO
Histone H4
Search

0.10	Histone H4 type VIII

0.76	GO:0006334	nucleosome assembly
0.68	GO:0006352	DNA-templated transcription, initiation

0.74	GO:0046982	protein heterodimerization activity
0.55	GO:0003677	DNA binding
0.40	GO:0042393	histone binding

0.75	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.37	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

tr|T1G5M4|T1G5M4_HELRO
Uncharacterized protein
Search

tr|T1G5M5|T1G5M5_HELRO
Uncharacterized protein
Search

CTNS

0.90	Cystinosin, lysosomal cystine transporter

0.59	GO:0015811	L-cystine transport
0.55	GO:0007625	grooming behavior
0.54	GO:0007628	adult walking behavior
0.54	GO:0008542	visual learning
0.54	GO:0007616	long-term memory
0.53	GO:0002088	lens development in camera-type eye
0.50	GO:0007420	brain development
0.49	GO:0006749	glutathione metabolic process
0.43	GO:0046034	ATP metabolic process
0.40	GO:0010730	negative regulation of hydrogen peroxide biosynthetic process

0.59	GO:0015184	L-cystine transmembrane transporter activity
0.34	GO:0034639	L-amino acid efflux transmembrane transporter activity
0.33	GO:0003684	damaged DNA binding

0.53	GO:0005765	lysosomal membrane
0.51	GO:0005770	late endosome
0.50	GO:0045111	intermediate filament cytoskeleton
0.37	GO:0070062	extracellular exosome
0.37	GO:0005769	early endosome
0.36	GO:0042470	melanosome
0.34	GO:0045335	phagocytic vesicle
0.34	GO:0005886	plasma membrane
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

tr|T1G5M6|T1G5M6_HELRO
Uncharacterized protein
Search

COX17

0.91	Mitochondrial cytochrome c oxidase copper chaperone

0.78	GO:0006825	copper ion transport
0.50	GO:0033617	mitochondrial respiratory chain complex IV assembly
0.49	GO:1904734	positive regulation of electron transfer activity
0.49	GO:1904959	regulation of cytochrome-c oxidase activity
0.46	GO:0032414	positive regulation of ion transmembrane transporter activity
0.46	GO:1904064	positive regulation of cation transmembrane transport
0.45	GO:0008284	positive regulation of cell proliferation
0.41	GO:0046688	response to copper ion
0.37	GO:0007507	heart development
0.37	GO:0007420	brain development

0.85	GO:0016531	copper chaperone activity
0.48	GO:1903136	cuprous ion binding
0.37	GO:0001104	RNA polymerase II transcription cofactor activity
0.35	GO:0008047	enzyme activator activity
0.34	GO:0030170	pyridoxal phosphate binding
0.34	GO:0003677	DNA binding
0.33	GO:0004386	helicase activity
0.33	GO:0005515	protein binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding

0.79	GO:0005758	mitochondrial intermembrane space
0.37	GO:0005634	nucleus
0.35	GO:0043234	protein complex
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|T1G5M7|T1G5M7_HELRO
Uncharacterized protein
Search

0.53	52 kDa repressor of the inhibitor of the protein kinase

0.56

GO:0016310

phosphorylation

0.68	GO:0046983	protein dimerization activity
0.59	GO:0016301	kinase activity

tr|T1G5M8|T1G5M8_HELRO
Uncharacterized protein
Search

tr|T1G5M9|T1G5M9_HELRO
Uncharacterized protein
Search

0.48	DUF872-domain-containing protein

0.36	GO:0007264	small GTPase mediated signal transduction
0.35	GO:0065009	regulation of molecular function

0.36	GO:0005085	guanyl-nucleotide exchange factor activity
0.35	GO:0032550	purine ribonucleoside binding
0.35	GO:0019001	guanyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.32	GO:0005622	intracellular
0.30	GO:0044425	membrane part

tr|T1G5N0|T1G5N0_HELRO
Uncharacterized protein
Search

FURIN

0.80	Truncated furin endoprotease

0.61	GO:0006508	proteolysis
0.55	GO:0032804	negative regulation of low-density lipoprotein particle receptor catabolic process
0.55	GO:0032902	nerve growth factor production
0.55	GO:0032911	negative regulation of transforming growth factor beta1 production
0.54	GO:0045714	regulation of low-density lipoprotein particle receptor biosynthetic process
0.50	GO:0042445	hormone metabolic process
0.50	GO:0008283	cell proliferation
0.49	GO:0051604	protein maturation
0.48	GO:0010951	negative regulation of endopeptidase activity
0.46	GO:0032940	secretion by cell

0.69	GO:0004252	serine-type endopeptidase activity
0.55	GO:0048406	nerve growth factor binding
0.52	GO:0002020	protease binding
0.49	GO:0042277	peptide binding
0.49	GO:0004867	serine-type endopeptidase inhibitor activity
0.39	GO:0005102	receptor binding
0.35	GO:0046872	metal ion binding
0.32	GO:0043140	ATP-dependent 3'-5' DNA helicase activity
0.31	GO:0030554	adenyl nucleotide binding
0.31	GO:0003677	DNA binding

0.51	GO:0030140	trans-Golgi network transport vesicle
0.50	GO:0098857	membrane microdomain
0.50	GO:0005802	trans-Golgi network
0.48	GO:0009986	cell surface
0.47	GO:0000139	Golgi membrane
0.46	GO:0005783	endoplasmic reticulum
0.40	GO:0043025	neuronal cell body
0.39	GO:0010008	endosome membrane
0.37	GO:0005576	extracellular region
0.35	GO:0005886	plasma membrane

0.69

GO:0004252

tr|T1G5N1|T1G5N1_HELRO
Uncharacterized protein
Search

tr|T1G5N2|T1G5N2_HELRO
Uncharacterized protein
Search

0.58	39S ribosomal protein L54, mitochondrial

0.43	GO:0032543	mitochondrial translation
0.38	GO:0006030	chitin metabolic process
0.37	GO:0051603	proteolysis involved in cellular protein catabolic process
0.35	GO:0005975	carbohydrate metabolic process

0.38	GO:0003735	structural constituent of ribosome
0.38	GO:0070003	threonine-type peptidase activity
0.38	GO:0008061	chitin binding
0.36	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.36	GO:0004175	endopeptidase activity

0.61	GO:0005840	ribosome
0.41	GO:0005759	mitochondrial matrix
0.38	GO:0005839	proteasome core complex
0.36	GO:0005576	extracellular region

0.36

GO:0004553

tr|T1G5N3|T1G5N3_HELRO
Uncharacterized protein
Search

ACPP

0.80	Prostatic acid phosphatase

0.59	GO:0060168	positive regulation of adenosine receptor signaling pathway
0.57	GO:0051930	regulation of sensory perception of pain
0.56	GO:0046085	adenosine metabolic process
0.51	GO:0051289	protein homotetramerization
0.50	GO:0016311	dephosphorylation
0.49	GO:0006772	thiamine metabolic process
0.46	GO:0006144	purine nucleobase metabolic process
0.42	GO:0007040	lysosome organization
0.41	GO:0001501	skeletal system development
0.41	GO:0009117	nucleotide metabolic process

0.59	GO:0052642	lysophosphatidic acid phosphatase activity
0.58	GO:0042131	thiamine phosphate phosphatase activity
0.52	GO:0008253	5'-nucleotidase activity
0.47	GO:0042803	protein homodimerization activity
0.35	GO:0033265	choline binding
0.34	GO:0005509	calcium ion binding
0.32	GO:0046961	proton-transporting ATPase activity, rotational mechanism
0.31	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.50	GO:0012506	vesicle membrane
0.50	GO:0030175	filopodium
0.49	GO:0005615	extracellular space
0.44	GO:0005764	lysosome
0.42	GO:0005886	plasma membrane
0.39	GO:0098852	lytic vacuole membrane
0.37	GO:0005775	vacuolar lumen
0.36	GO:0030141	secretory granule
0.36	GO:1903561	extracellular vesicle
0.35	GO:0005771	multivesicular body

0.52

EC:3.1.3.5

GO:0008253

tr|T1G5N4|T1G5N4_HELRO
Uncharacterized protein
Search

0.12	TP53-regulated inhibitor of apoptosis 1

0.66	GO:0033108	mitochondrial respiratory chain complex assembly
0.66	GO:0045332	phospholipid translocation

0.79

GO:0005758

mitochondrial intermembrane space

tr|T1G5N5|T1G5N5_HELRO
Uncharacterized protein
Search

tr|T1G5N6|T1G5N6_HELRO
Uncharacterized protein
Search

PKD2L1

0.83	Polycystin 2 like 1, transient receptor potential cation channel

0.55	GO:0009612	response to mechanical stimulus
0.53	GO:0070588	calcium ion transmembrane transport
0.52	GO:0072059	cortical collecting duct development
0.52	GO:0072055	renal cortex development
0.52	GO:0071464	cellular response to hydrostatic pressure
0.52	GO:0061441	renal artery morphogenesis
0.52	GO:0051260	protein homooligomerization
0.52	GO:0072208	metanephric smooth muscle tissue development
0.52	GO:0031587	positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
0.51	GO:0072218	metanephric ascending thin limb development

0.70	GO:0005509	calcium ion binding
0.54	GO:0005262	calcium channel activity
0.54	GO:0042805	actinin binding
0.53	GO:0005272	sodium channel activity
0.51	GO:0098782	mechanosensitived potassium channel activity
0.51	GO:0043398	HLH domain binding
0.50	GO:0033040	sour taste receptor activity
0.50	GO:0042802	identical protein binding
0.49	GO:0044325	ion channel binding
0.48	GO:0051219	phosphoprotein binding

0.53	GO:0097730	non-motile cilium
0.51	GO:0002133	polycystin complex
0.50	GO:0045180	basal cortex
0.50	GO:0071458	integral component of cytoplasmic side of endoplasmic reticulum membrane
0.50	GO:0071556	integral component of lumenal side of endoplasmic reticulum membrane
0.49	GO:0009925	basal plasma membrane
0.49	GO:0031941	filamentous actin
0.49	GO:0060170	ciliary membrane
0.48	GO:0036064	ciliary basal body
0.48	GO:0030027	lamellipodium

0.33

GO:0016887

tr|T1G5N7|T1G5N7_HELRO
Uncharacterized protein
Search

FUT10

0.78	Alpha-(1,3)-fucosyltransferase

0.81	GO:0036065	fucosylation
0.74	GO:0006486	protein glycosylation
0.50	GO:0097150	neuronal stem cell population maintenance
0.50	GO:0021799	cerebral cortex radially oriented cell migration
0.34	GO:0042355	L-fucose catabolic process
0.34	GO:0009566	fertilization
0.34	GO:0042060	wound healing
0.34	GO:0016579	protein deubiquitination
0.34	GO:0030097	hemopoiesis
0.33	GO:0006605	protein targeting

0.84	GO:0046920	alpha-(1->3)-fucosyltransferase activity
0.34	GO:0004843	thiol-dependent ubiquitin-specific protease activity

0.80	GO:0032580	Golgi cisterna membrane
0.46	GO:0005783	endoplasmic reticulum
0.46	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.84

GO:0046920

tr|T1G5N8|T1G5N8_HELRO
Uncharacterized protein
Search

0.69	NPC intracellular cholesterol transporter 2

0.85	GO:0032367	intracellular cholesterol transport
0.52	GO:0055092	sterol homeostasis
0.52	GO:0045456	ecdysteroid biosynthetic process
0.52	GO:0061057	peptidoglycan recognition protein signaling pathway
0.51	GO:0008039	synaptic target recognition
0.42	GO:0033344	cholesterol efflux
0.40	GO:0009615	response to virus
0.35	GO:0016192	vesicle-mediated transport

0.53	GO:0030882	lipid antigen binding
0.53	GO:0070891	lipoteichoic acid binding
0.49	GO:0001530	lipopolysaccharide binding
0.47	GO:0042834	peptidoglycan binding
0.43	GO:0032934	sterol binding
0.42	GO:0017127	cholesterol transporter activity
0.41	GO:0043178	alcohol binding
0.39	GO:0019899	enzyme binding

0.48	GO:0005615	extracellular space
0.45	GO:0005622	intracellular
0.35	GO:0043227	membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

tr|T1G5N9|T1G5N9_HELRO
Uncharacterized protein
Search

tr|T1G5P0|T1G5P0_HELRO
Uncharacterized protein
Search

0.70	GO:0018108	peptidyl-tyrosine phosphorylation
0.47	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.44	GO:0038065	collagen-activated signaling pathway
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:0010468	regulation of gene expression
0.34	GO:0005975	carbohydrate metabolic process

0.70	GO:0004713	protein tyrosine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0019199	transmembrane receptor protein kinase activity
0.45	GO:0038064	collagen receptor activity
0.39	GO:0004674	protein serine/threonine kinase activity
0.37	GO:0003700	DNA binding transcription factor activity
0.36	GO:0003677	DNA binding
0.34	GO:0030246	carbohydrate binding

0.39

GO:0005887

integral component of plasma membrane

0.70

GO:0004713

tr|T1G5P1|T1G5P1_HELRO
Uncharacterized protein
Search

0.86	NADH dehydrogenase 1 beta subcomplex 8 (Fragment)

0.62	GO:0006120	mitochondrial electron transport, NADH to ubiquinone
0.42	GO:0032981	mitochondrial respiratory chain complex I assembly
0.34	GO:0006626	protein targeting to mitochondrion

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.67	GO:0005747	mitochondrial respiratory chain complex I
0.36	GO:0005783	endoplasmic reticulum
0.34	GO:0005759	mitochondrial matrix
0.30	GO:0016021	integral component of membrane

0.69

GO:0008137

tr|T1G5P2|T1G5P2_HELRO
Fatty acyl-CoA reductase
Search

0.58	Fatty acyl-CoA reductase

0.62	GO:0006629	lipid metabolic process
0.54	GO:0035336	long-chain fatty-acyl-CoA metabolic process
0.54	GO:0010025	wax biosynthetic process
0.52	GO:0055114	oxidation-reduction process
0.52	GO:0046504	glycerol ether biosynthetic process
0.42	GO:0090407	organophosphate biosynthetic process
0.39	GO:0006796	phosphate-containing compound metabolic process
0.33	GO:0006879	cellular iron ion homeostasis

0.83	GO:0102965	alcohol-forming fatty acyl-CoA reductase activity
0.82	GO:0080019	fatty-acyl-CoA reductase (alcohol-forming) activity
0.33	GO:0008199	ferric iron binding

0.50	GO:0005777	peroxisome
0.49	GO:0031903	microbody membrane
0.48	GO:0031301	integral component of organelle membrane
0.34	GO:0031907	microbody lumen

tr|T1G5P3|T1G5P3_HELRO
Uncharacterized protein
Search

MAGOH

0.91	RNA-binding protein Mago nashi

0.50	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.46	GO:0008380	RNA splicing
0.45	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.40	GO:0051028	mRNA transport
0.39	GO:0006397	mRNA processing
0.37	GO:0006417	regulation of translation
0.36	GO:0010183	pollen tube guidance
0.36	GO:0006369	termination of RNA polymerase II transcription
0.35	GO:0009793	embryo development ending in seed dormancy
0.35	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus

0.37	GO:0003723	RNA binding
0.34	GO:0005515	protein binding
0.34	GO:0005044	scavenger receptor activity

0.61	GO:0005634	nucleus
0.44	GO:0043234	protein complex
0.43	GO:0044446	intracellular organelle part
0.42	GO:1902494	catalytic complex
0.42	GO:0030529	intracellular ribonucleoprotein complex
0.38	GO:0031974	membrane-enclosed lumen
0.37	GO:0043025	neuronal cell body
0.34	GO:0005737	cytoplasm
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

tr|T1G5P4|T1G5P4_HELRO
Uncharacterized protein
Search

0.38	GO:0006606	protein import into nucleus
0.38	GO:0071426	ribonucleoprotein complex export from nucleus
0.35	GO:0070647	protein modification by small protein conjugation or removal
0.34	GO:0009165	nucleotide biosynthetic process
0.34	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.34	GO:0009206	purine ribonucleoside triphosphate biosynthetic process
0.34	GO:0070143	mitochondrial alanyl-tRNA aminoacylation
0.33	GO:0009168	purine ribonucleoside monophosphate biosynthetic process
0.33	GO:0006508	proteolysis
0.33	GO:0072522	purine-containing compound biosynthetic process

0.57	GO:0017056	structural constituent of nuclear pore
0.37	GO:0005543	phospholipid binding
0.35	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.34	GO:0004842	ubiquitin-protein transferase activity
0.34	GO:0008080	N-acetyltransferase activity
0.33	GO:0004983	neuropeptide Y receptor activity
0.33	GO:0008270	zinc ion binding
0.33	GO:0015078	hydrogen ion transmembrane transporter activity
0.33	GO:0004813	alanine-tRNA ligase activity
0.33	GO:0016849	phosphorus-oxygen lyase activity

0.56	GO:0005643	nuclear pore
0.34	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
0.32	GO:0015934	large ribosomal subunit
0.32	GO:0009507	chloroplast
0.30	GO:0016021	integral component of membrane

0.34	EC:2.3.1	GO:0008080
0.34	KEGG:R03876	GO:0004842

tr|T1G5P5|T1G5P5_HELRO
Uncharacterized protein
Search

0.71	Putative microtubule associated complex

0.81	GO:0007064	mitotic sister chromatid cohesion
0.51	GO:1900262	regulation of DNA-directed DNA polymerase activity
0.50	GO:2000573	positive regulation of DNA biosynthetic process
0.47	GO:0051347	positive regulation of transferase activity
0.37	GO:0006259	DNA metabolic process
0.36	GO:0006367	transcription initiation from RNA polymerase II promoter
0.35	GO:0032392	DNA geometric change
0.35	GO:0046856	phosphatidylinositol dephosphorylation
0.35	GO:0006974	cellular response to DNA damage stimulus

0.49	GO:0003689	DNA clamp loader activity
0.49	GO:0043142	single-stranded DNA-dependent ATPase activity
0.36	GO:0004003	ATP-dependent DNA helicase activity
0.35	GO:0034597	phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.83	GO:0031390	Ctf18 RFC-like complex
0.36	GO:0005634	nucleus
0.35	GO:0070062	extracellular exosome
0.34	GO:0031974	membrane-enclosed lumen
0.30	GO:0016020	membrane

0.35

EC:3.1.3.66

GO:0034597

tr|T1G5P6|T1G5P6_HELRO
Uncharacterized protein
Search

0.45	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.45	GO:1903506	regulation of nucleic acid-templated transcription
0.44	GO:0010468	regulation of gene expression

0.55

GO:0003677

DNA binding

0.61

GO:0005634

nucleus

tr|T1G5P7|T1G5P7_HELRO
Uncharacterized protein
Search

0.72	Putative ubiquitin carboxyl-terminal hydrolase 6

0.66	GO:0031338	regulation of vesicle fusion
0.66	GO:0090630	activation of GTPase activity
0.58	GO:0035526	retrograde transport, plasma membrane to Golgi
0.57	GO:0048227	plasma membrane to endosome transport
0.56	GO:1903358	regulation of Golgi organization
0.56	GO:0006886	intracellular protein transport
0.53	GO:0007030	Golgi organization
0.48	GO:0019068	virion assembly

0.68	GO:0017137	Rab GTPase binding
0.65	GO:0005096	GTPase activator activity
0.44	GO:0016787	hydrolase activity

0.54	GO:0012505	endomembrane system
0.49	GO:0031410	cytoplasmic vesicle
0.41	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.44

GO:0016787

tr|T1G5P8|T1G5P8_HELRO
Uncharacterized protein
Search

PFDN2

0.82	Prefoldin subunit

0.69	GO:0006457	protein folding
0.48	GO:0051495	positive regulation of cytoskeleton organization
0.43	GO:0007021	tubulin complex assembly
0.34	GO:0007155	cell adhesion
0.33	GO:0030260	entry into host cell
0.33	GO:0019058	viral life cycle

0.71	GO:0051082	unfolded protein binding
0.55	GO:0044183	protein binding involved in protein folding
0.41	GO:0015631	tubulin binding

0.80	GO:0016272	prefoldin complex
0.45	GO:0005829	cytosol
0.42	GO:0005634	nucleus
0.41	GO:0005739	mitochondrion
0.34	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

tr|T1G5P9|T1G5P9_HELRO
Uncharacterized protein
Search

0.75	Myocyte enhancer factor 2b (Fragment)

0.73	GO:0045944	positive regulation of transcription by RNA polymerase II
0.58	GO:0006351	transcription, DNA-templated
0.38	GO:0014056	regulation of acetylcholine secretion, neurotransmission
0.36	GO:0000122	negative regulation of transcription by RNA polymerase II
0.35	GO:0036076	ligamentous ossification
0.35	GO:0030241	skeletal muscle myosin thick filament assembly
0.35	GO:0060536	cartilage morphogenesis
0.35	GO:0060914	heart formation
0.35	GO:0055013	cardiac muscle cell development
0.34	GO:0060349	bone morphogenesis

0.76	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.68	GO:0046983	protein dimerization activity
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.33	GO:0003723	RNA binding
0.33	GO:0046872	metal ion binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.34

GO:0032440

tr|T1G5Q0|T1G5Q0_HELRO
Uncharacterized protein
Search

tr|T1G5Q1|T1G5Q1_HELRO
Uncharacterized protein
Search

0.79	GO:0006367	transcription initiation from RNA polymerase II promoter
0.54	GO:0030100	regulation of endocytosis
0.51	GO:0006897	endocytosis
0.44	GO:0070897	DNA-templated transcriptional preinitiation complex assembly
0.42	GO:0045944	positive regulation of transcription by RNA polymerase II
0.41	GO:0006413	translational initiation
0.37	GO:0050890	cognition
0.35	GO:0006886	intracellular protein transport

0.50	GO:0003713	transcription coactivator activity
0.46	GO:0001094	TFIID-class transcription factor binding
0.45	GO:0001129	RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly
0.45	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.44	GO:0017025	TBP-class protein binding
0.43	GO:0001104	RNA polymerase II transcription cofactor activity
0.41	GO:0003743	translation initiation factor activity
0.33	GO:0003677	DNA binding

0.83	GO:0005672	transcription factor TFIIA complex
0.36	GO:0030117	membrane coat

tr|T1G5Q2|T1G5Q2_HELRO
Uncharacterized protein
Search

0.53	Forkhead transcription factor HCM1 (Fragment)

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.39	GO:0006351	transcription, DNA-templated
0.38	GO:0030154	cell differentiation
0.38	GO:0009653	anatomical structure morphogenesis
0.33	GO:0007186	G-protein coupled receptor signaling pathway

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.40	GO:0050825	ice binding
0.33	GO:0004930	G-protein coupled receptor activity
0.33	GO:0030246	carbohydrate binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|T1G5Q3|T1G5Q3_HELRO
Uncharacterized protein
Search

0.50	GO:0007412	axon target recognition
0.50	GO:0045570	regulation of imaginal disc growth
0.49	GO:0008345	larval locomotory behavior
0.49	GO:0048190	wing disc dorsal/ventral pattern formation
0.49	GO:0045879	negative regulation of smoothened signaling pathway
0.48	GO:0007476	imaginal disc-derived wing morphogenesis
0.46	GO:0007411	axon guidance
0.46	GO:0000122	negative regulation of transcription by RNA polymerase II
0.34	GO:0051568	histone H3-K4 methylation
0.33	GO:0006413	translational initiation

0.50	GO:0003676	nucleic acid binding
0.47	GO:0003714	transcription corepressor activity
0.34	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.34	GO:0005515	protein binding
0.32	GO:0046872	metal ion binding

0.40	GO:0005634	nucleus
0.34	GO:0034708	methyltransferase complex
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

tr|T1G5Q4|T1G5Q4_HELRO
Uncharacterized protein
Search

tr|T1G5Q5|T1G5Q5_HELRO
Uncharacterized protein
Search

FUCTA

0.76	Glycoprotein 3-alpha-L-fucosyltransferase A

0.81	GO:0036065	fucosylation
0.74	GO:0006486	protein glycosylation
0.42	GO:0007399	nervous system development
0.34	GO:0009165	nucleotide biosynthetic process
0.34	GO:0006259	DNA metabolic process
0.33	GO:0006508	proteolysis
0.32	GO:0006352	DNA-templated transcription, initiation
0.32	GO:0016310	phosphorylation
0.32	GO:0019674	NAD metabolic process
0.32	GO:0006739	NADP metabolic process

0.81	GO:0008417	fucosyltransferase activity
0.49	GO:0033932	1,3-alpha-L-fucosidase activity
0.47	GO:0140103	catalytic activity, acting on a glycoprotein
0.36	GO:0004531	deoxyribonuclease II activity
0.36	GO:0004749	ribose phosphate diphosphokinase activity
0.34	GO:0000287	magnesium ion binding
0.34	GO:0017171	serine hydrolase activity
0.33	GO:0070011	peptidase activity, acting on L-amino acid peptides
0.33	GO:0005509	calcium ion binding
0.33	GO:0046982	protein heterodimerization activity

0.81	GO:0032580	Golgi cisterna membrane
0.46	GO:0005797	Golgi medial cisterna
0.33	GO:0005669	transcription factor TFIID complex
0.33	GO:0009986	cell surface
0.32	GO:0071944	cell periphery
0.30	GO:0031224	intrinsic component of membrane

0.81	EC:2.4.1	GO:0008417
0.36	KEGG:R01049	GO:0004749

tr|T1G5Q6|T1G5Q6_HELRO
Uncharacterized protein
Search

tr|T1G5Q7|T1G5Q7_HELRO
Uncharacterized protein
Search

0.32	Fatty alcohol acetyltransferase

0.71

GO:0006897

endocytosis

0.41

GO:0016746

transferase activity, transferring acyl groups

0.49

GO:0005737

cytoplasm

0.41

EC:2.3

GO:0016746

tr|T1G5Q8|T1G5Q8_HELRO
Uncharacterized protein
Search

0.63	GO:0007049	cell cycle
0.55	GO:0006351	transcription, DNA-templated
0.54	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.46	GO:0051726	regulation of cell cycle
0.46	GO:0030433	ubiquitin-dependent ERAD pathway

0.52	GO:0003677	DNA binding
0.51	GO:0046872	metal ion binding
0.46	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.44	GO:0043233	organelle lumen
0.42	GO:0005783	endoplasmic reticulum
0.40	GO:0044446	intracellular organelle part

tr|T1G5Q9|T1G5Q9_HELRO
Uncharacterized protein
Search

SOS2

0.64	Son of sevenless homolog 2

0.77	GO:0007264	small GTPase mediated signal transduction
0.76	GO:0035023	regulation of Rho protein signal transduction
0.66	GO:0065009	regulation of molecular function
0.36	GO:2000973	regulation of pro-B cell differentiation
0.36	GO:0033081	regulation of T cell differentiation in thymus
0.36	GO:0001782	B cell homeostasis
0.36	GO:1904693	midbrain morphogenesis
0.36	GO:0042129	regulation of T cell proliferation
0.35	GO:0007296	vitellogenesis
0.35	GO:0051057	positive regulation of small GTPase mediated signal transduction

0.76	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.71	GO:0046982	protein heterodimerization activity
0.52	GO:0003677	DNA binding
0.33	GO:0017124	SH3 domain binding
0.32	GO:0005096	GTPase activator activity
0.32	GO:0003735	structural constituent of ribosome

0.48	GO:0000786	nucleosome
0.43	GO:0005634	nucleus
0.34	GO:0014069	postsynaptic density
0.33	GO:0043025	neuronal cell body
0.33	GO:0005829	cytosol
0.32	GO:0005886	plasma membrane
0.32	GO:0005840	ribosome

tr|T1G5R0|T1G5R0_HELRO
Uncharacterized protein
Search

tr|T1G5R1|T1G5R1_HELRO
Uncharacterized protein
Search

tr|T1G5R2|T1G5R2_HELRO
Uncharacterized protein
Search

0.48	GO:0007596	blood coagulation
0.46	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.45	GO:0098656	anion transmembrane transport
0.45	GO:0015698	inorganic anion transport
0.44	GO:0071805	potassium ion transmembrane transport
0.43	GO:0015074	DNA integration
0.40	GO:0055114	oxidation-reduction process

0.51	GO:0005452	inorganic anion exchanger activity
0.50	GO:0003995	acyl-CoA dehydrogenase activity
0.46	GO:0050660	flavin adenine dinucleotide binding
0.46	GO:0032550	purine ribonucleoside binding
0.46	GO:0019001	guanyl nucleotide binding
0.45	GO:0005267	potassium channel activity
0.43	GO:0005509	calcium ion binding
0.41	GO:0032555	purine ribonucleotide binding
0.41	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0003677	DNA binding

0.30

GO:0016020

membrane

0.50

EC:1.3.99.3

GO:0003995

tr|T1G5R3|T1G5R3_HELRO
Uncharacterized protein
Search

tr|T1G5R4|T1G5R4_HELRO
Uncharacterized protein
Search

tr|T1G5R5|T1G5R5_HELRO
Uncharacterized protein
Search

0.76	PRKR-interacting protein 1

0.77	GO:0006469	negative regulation of protein kinase activity
0.37	GO:0016310	phosphorylation

0.80	GO:0004860	protein kinase inhibitor activity
0.75	GO:0019901	protein kinase binding
0.74	GO:0003725	double-stranded RNA binding
0.38	GO:0016301	kinase activity

0.70	GO:0005730	nucleolus
0.30	GO:0031224	intrinsic component of membrane

tr|T1G5R6|T1G5R6_HELRO
Uncharacterized protein
Search

0.20	Aminopeptidase

0.67	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I
0.59	GO:0006508	proteolysis
0.58	GO:0008217	regulation of blood pressure
0.46	GO:0043171	peptide catabolic process
0.40	GO:0007267	cell-cell signaling
0.38	GO:0060177	regulation of angiotensin metabolic process
0.38	GO:0050886	endocrine process
0.37	GO:0007165	signal transduction
0.37	GO:0002250	adaptive immune response
0.36	GO:0042445	hormone metabolic process

0.70	GO:0004177	aminopeptidase activity
0.66	GO:0008237	metallopeptidase activity
0.62	GO:0008270	zinc ion binding
0.46	GO:0042277	peptide binding
0.33	GO:0004175	endopeptidase activity

0.56	GO:0005783	endoplasmic reticulum
0.51	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.49	GO:0031984	organelle subcompartment
0.36	GO:0005886	plasma membrane
0.33	GO:0043233	organelle lumen
0.30	GO:0016021	integral component of membrane

0.70

EC:3.4.11

GO:0004177

tr|T1G5R7|T1G5R7_HELRO
Uncharacterized protein
Search

tr|T1G5R8|T1G5R8_HELRO
Uncharacterized protein
Search

0.74	GO:0018108	peptidyl-tyrosine phosphorylation
0.57	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.42	GO:0046777	protein autophosphorylation
0.41	GO:2000369	regulation of clathrin-dependent endocytosis
0.40	GO:0042127	regulation of cell proliferation
0.40	GO:0001934	positive regulation of protein phosphorylation
0.40	GO:0032502	developmental process
0.39	GO:0050730	regulation of peptidyl-tyrosine phosphorylation
0.39	GO:0016477	cell migration
0.38	GO:0045087	innate immune response

0.74	GO:0004713	protein tyrosine kinase activity
0.58	GO:0019199	transmembrane receptor protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0032555	purine ribonucleotide binding
0.48	GO:0004712	protein serine/threonine/tyrosine kinase activity
0.41	GO:0070851	growth factor receptor binding
0.39	GO:0019899	enzyme binding
0.38	GO:0043560	insulin receptor substrate binding

0.41	GO:0044459	plasma membrane part
0.40	GO:0031410	cytoplasmic vesicle
0.39	GO:0005905	clathrin-coated pit
0.39	GO:0043202	lysosomal lumen
0.38	GO:0098562	cytoplasmic side of membrane
0.38	GO:0019898	extrinsic component of membrane
0.36	GO:0098796	membrane protein complex
0.36	GO:0005634	nucleus
0.35	GO:0030425	dendrite
0.35	GO:0030424	axon

0.74

GO:0004713

tr|T1G5R9|T1G5R9_HELRO
Uncharacterized protein
Search

0.46

GO:0006313

transposition, DNA-mediated

0.55	GO:0003677	DNA binding
0.46	GO:0004803	transposase activity

tr|T1G5S0|T1G5S0_HELRO
Uncharacterized protein
Search

0.53	Cell division cycle protein 123 like

0.67	GO:0007049	cell cycle
0.63	GO:0051301	cell division
0.40	GO:0045786	negative regulation of cell cycle
0.39	GO:0006417	regulation of translation

0.33	GO:0000287	magnesium ion binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032553	ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.36

GO:0005737

cytoplasm

tr|T1G5S1|T1G5S1_HELRO
Uncharacterized protein
Search

0.11	Galactocerebrosidase

0.86	GO:0006683	galactosylceramide catabolic process
0.34	GO:0045859	regulation of protein kinase activity

0.86	GO:0004336	galactosylceramidase activity
0.34	GO:0019887	protein kinase regulator activity
0.33	GO:0030246	carbohydrate binding

0.42	GO:0005764	lysosome
0.42	GO:0005739	mitochondrion
0.37	GO:0070062	extracellular exosome
0.35	GO:0005956	protein kinase CK2 complex
0.34	GO:0005775	vacuolar lumen
0.30	GO:0016020	membrane

0.86

EC:3.2.1.46

GO:0004336

tr|T1G5S2|T1G5S2_HELRO
Uncharacterized protein
Search

tr|T1G5S3|T1G5S3_HELRO
Uncharacterized protein
Search

tr|T1G5S4|T1G5S4_HELRO
Uncharacterized protein
Search

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.61	GO:0007194	negative regulation of adenylate cyclase activity
0.51	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.51	GO:1902606	regulation of large conductance calcium-activated potassium channel activity
0.49	GO:0045944	positive regulation of transcription by RNA polymerase II
0.49	GO:1901018	positive regulation of potassium ion transmembrane transporter activity
0.48	GO:2001259	positive regulation of cation channel activity
0.47	GO:0035587	purinergic receptor signaling pathway
0.46	GO:0032501	multicellular organismal process
0.45	GO:0120036	plasma membrane bounded cell projection organization

0.72	GO:0004930	G-protein coupled receptor activity
0.65	GO:0001653	peptide receptor activity
0.55	GO:0017046	peptide hormone binding
0.47	GO:0035586	purinergic receptor activity
0.42	GO:0042923	neuropeptide binding
0.34	GO:0005230	extracellular ligand-gated ion channel activity
0.33	GO:0004896	cytokine receptor activity
0.33	GO:0005515	protein binding

0.45	GO:0097730	non-motile cilium
0.45	GO:0005887	integral component of plasma membrane
0.38	GO:0043005	neuron projection
0.33	GO:0009986	cell surface
0.33	GO:0031966	mitochondrial membrane
0.33	GO:0019866	organelle inner membrane

tr|T1G5S5|T1G5S5_HELRO
Uncharacterized protein
Search

0.91	Putative HAT, C-terminal dimerization domain-containing protein

0.68

GO:0046983

protein dimerization activity

tr|T1G5S6|T1G5S6_HELRO
Uncharacterized protein
Search

0.56	Threonyl-tRNA synthetase

0.78	GO:0006435	threonyl-tRNA aminoacylation
0.42	GO:0006506	GPI anchor biosynthetic process
0.36	GO:0001569	branching involved in blood vessel morphogenesis
0.36	GO:1903670	regulation of sprouting angiogenesis

0.79	GO:0004829	threonine-tRNA ligase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.49	GO:0005737	cytoplasm
0.40	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.39	GO:0031984	organelle subcompartment
0.37	GO:0043231	intracellular membrane-bounded organelle
0.36	GO:0015629	actin cytoskeleton
0.30	GO:0016021	integral component of membrane

0.79

EC:6.1.1.3

GO:0004829

tr|T1G5S7|T1G5S7_HELRO
Uncharacterized protein
Search

0.45	GO:1990954	establishment of protein localization to meiotic spindle pole body
0.43	GO:0090307	mitotic spindle assembly
0.42	GO:0031322	ascospore-type prospore-specific spindle pole body remodeling
0.32	GO:0055114	oxidation-reduction process

0.70	GO:0005509	calcium ion binding
0.36	GO:0070855	myosin VI head/neck binding
0.35	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.33	GO:0016887	ATPase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.44	GO:0035840	old growing cell tip
0.44	GO:0035841	new growing cell tip
0.44	GO:0035974	meiotic spindle pole body
0.43	GO:0000935	division septum
0.43	GO:0044732	mitotic spindle pole body
0.42	GO:0043332	mating projection tip
0.38	GO:0031514	motile cilium
0.36	GO:0031476	myosin VI complex
0.36	GO:0070865	investment cone
0.33	GO:0005634	nucleus

0.35

GO:0032440

tr|T1G5S8|T1G5S8_HELRO
Uncharacterized protein
Search

tr|T1G5S9|T1G5S9_HELRO
Uncharacterized protein
Search

0.51	Polypeptide N-acetylgalactosaminyltransferase

0.72	GO:0043413	macromolecule glycosylation
0.72	GO:0009101	glycoprotein biosynthetic process
0.59	GO:0006464	cellular protein modification process
0.38	GO:0009312	oligosaccharide biosynthetic process
0.33	GO:0032504	multicellular organism reproduction

0.68	GO:0030246	carbohydrate binding
0.64	GO:0016757	transferase activity, transferring glycosyl groups
0.41	GO:0140096	catalytic activity, acting on a protein
0.34	GO:0046872	metal ion binding

0.72	GO:0000139	Golgi membrane
0.38	GO:0005783	endoplasmic reticulum
0.34	GO:0031985	Golgi cisterna
0.30	GO:0031224	intrinsic component of membrane

0.64

GO:0016757

tr|T1G5T0|T1G5T0_HELRO
UDP-glucuronosyltransferase
Search

0.28	UDP-glucuronosyltransferase

0.41	GO:0016999	antibiotic metabolic process
0.33	GO:0055114	oxidation-reduction process

0.69	GO:0016758	transferase activity, transferring hexosyl groups
0.61	GO:0008194	UDP-glycosyltransferase activity
0.33	GO:0016491	oxidoreductase activity

0.38	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0044425	membrane part

0.69

GO:0016758

tr|T1G5T1|T1G5T1_HELRO
Uncharacterized protein
Search

tr|T1G5T2|T1G5T2_HELRO
Uncharacterized protein
Search

tr|T1G5T3|T1G5T3_HELRO
Uncharacterized protein
Search

0.72	Actin regulatory protein CAP-G

0.39	GO:0051693	actin filament capping
0.39	GO:0007010	cytoskeleton organization
0.38	GO:0051014	actin filament severing
0.37	GO:0097435	supramolecular fiber organization
0.37	GO:0051261	protein depolymerization
0.36	GO:2000012	regulation of auxin polar transport
0.35	GO:0009630	gravitropism
0.35	GO:0001558	regulation of cell growth
0.34	GO:1905806	regulation of synapse disassembly
0.34	GO:0009734	auxin-activated signaling pathway

0.78	GO:0051015	actin filament binding
0.35	GO:0005543	phospholipid binding
0.35	GO:0048306	calcium-dependent protein binding
0.34	GO:0003785	actin monomer binding
0.33	GO:0005509	calcium ion binding

0.36	GO:0005856	cytoskeleton
0.34	GO:0045335	phagocytic vesicle
0.34	GO:0055120	striated muscle dense body
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

tr|T1G5T4|T1G5T4_HELRO
Actin-related protein 2/3 complex subunit 5
Search

0.71	Actin-related protein 2/3 complex subunit 5

0.80	GO:0034314	Arp2/3 complex-mediated actin nucleation
0.51	GO:0016477	cell migration
0.38	GO:0021769	orbitofrontal cortex development
0.38	GO:0051639	actin filament network formation
0.37	GO:0030011	maintenance of cell polarity
0.37	GO:0097581	lamellipodium organization
0.37	GO:0061842	microtubule organizing center localization
0.35	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.34	GO:0043312	neutrophil degranulation
0.34	GO:0048013	ephrin receptor signaling pathway

0.52	GO:0051015	actin filament binding
0.47	GO:0005200	structural constituent of cytoskeleton

0.80	GO:0005885	Arp2/3 protein complex
0.49	GO:0030027	lamellipodium
0.37	GO:0030426	growth cone
0.37	GO:0005737	cytoplasm
0.37	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.35	GO:0097708	intracellular vesicle
0.35	GO:0012505	endomembrane system
0.34	GO:0031983	vesicle lumen
0.33	GO:0070013	intracellular organelle lumen

tr|T1G5T5|T1G5T5_HELRO
Protein Wnt
Search

tr|T1G5T6|T1G5T6_HELRO
Uncharacterized protein
Search

0.10	Zinc finger protein 598

0.35	GO:0072344	rescue of stalled ribosome
0.35	GO:0006513	protein monoubiquitination

0.50	GO:0003676	nucleic acid binding
0.34	GO:0061630	ubiquitin protein ligase activity
0.34	GO:0043022	ribosome binding

tr|T1G5T7|T1G5T7_HELRO
Meiotic nuclear division protein 1 homolog
Search

MND1

0.81	Meiotic nuclear division protein 1

0.50	GO:0007131	reciprocal meiotic recombination
0.48	GO:0006302	double-strand break repair
0.34	GO:0010212	response to ionizing radiation
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:2001141	regulation of RNA biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.46	GO:0003690	double-stranded DNA binding
0.35	GO:0008270	zinc ion binding
0.33	GO:0005515	protein binding

0.59	GO:0005634	nucleus
0.32	GO:0005737	cytoplasm

tr|T1G5T8|T1G5T8_HELRO
Uncharacterized protein
Search

0.76

GO:0010951

negative regulation of endopeptidase activity

0.79

GO:0004867

serine-type endopeptidase inhibitor activity

0.59	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

tr|T1G5T9|T1G5T9_HELRO
Rabphilin
Search

RPH3AL

0.86

Rabphilin

0.76	GO:0017157	regulation of exocytosis
0.69	GO:0006886	intracellular protein transport
0.52	GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway
0.51	GO:0006887	exocytosis
0.49	GO:0042593	glucose homeostasis
0.42	GO:0050714	positive regulation of protein secretion
0.41	GO:0048489	synaptic vesicle transport
0.41	GO:0099504	synaptic vesicle cycle
0.41	GO:0099643	signal release from synapse
0.41	GO:0099531	presynaptic process involved in chemical synaptic transmission

0.81	GO:0017137	Rab GTPase binding
0.53	GO:0046872	metal ion binding
0.48	GO:0005544	calcium-dependent phospholipid binding
0.38	GO:0030274	LIM domain binding
0.37	GO:0019905	syntaxin binding
0.36	GO:0030276	clathrin binding
0.34	GO:0008092	cytoskeletal protein binding

0.50	GO:0098793	presynapse
0.50	GO:0099503	secretory vesicle
0.49	GO:0030133	transport vesicle
0.38	GO:0005886	plasma membrane
0.38	GO:0030659	cytoplasmic vesicle membrane
0.37	GO:0098805	whole membrane
0.37	GO:0098588	bounding membrane of organelle
0.33	GO:0030054	cell junction
0.30	GO:0016021	integral component of membrane

tr|T1G5U0|T1G5U0_HELRO
Uncharacterized protein
Search

tr|T1G5U1|T1G5U1_HELRO
Uncharacterized protein
Search

tr|T1G5U2|T1G5U2_HELRO
Uncharacterized protein
Search

0.44	Matrix metalloproteinase

0.61	GO:0006508	proteolysis
0.60	GO:0030574	collagen catabolic process
0.55	GO:0007275	multicellular organism development
0.48	GO:0022617	extracellular matrix disassembly
0.46	GO:0003416	endochondral bone growth
0.46	GO:0036075	replacement ossification
0.45	GO:0061448	connective tissue development
0.43	GO:0009653	anatomical structure morphogenesis
0.41	GO:0071711	basement membrane organization
0.40	GO:0045599	negative regulation of fat cell differentiation

0.70	GO:0004222	metalloendopeptidase activity
0.63	GO:0008270	zinc ion binding
0.47	GO:0005518	collagen binding
0.43	GO:0005509	calcium ion binding
0.35	GO:0001047	core promoter binding
0.35	GO:0004252	serine-type endopeptidase activity
0.34	GO:0001968	fibronectin binding
0.34	GO:0050750	low-density lipoprotein particle receptor binding
0.34	GO:0043565	sequence-specific DNA binding
0.34	GO:0048306	calcium-dependent protein binding

0.74	GO:0031012	extracellular matrix
0.36	GO:0005615	extracellular space
0.35	GO:0005581	collagen trimer
0.34	GO:0005634	nucleus
0.34	GO:0046581	intercellular canaliculus
0.33	GO:0005764	lysosome
0.33	GO:0005794	Golgi apparatus
0.33	GO:0031225	anchored component of membrane
0.32	GO:0005694	chromosome
0.32	GO:0070013	intracellular organelle lumen

0.70

GO:0004222

tr|T1G5U3|T1G5U3_HELRO
Uncharacterized protein
Search

tr|T1G5U4|T1G5U4_HELRO
Uncharacterized protein
Search

JKAMP

0.69	Medulloblastoma antigen MU-MB-50.4

0.83	GO:0006986	response to unfolded protein
0.37	GO:0030433	ubiquitin-dependent ERAD pathway

0.36	GO:0031625	ubiquitin protein ligase binding
0.33	GO:0003677	DNA binding

0.34	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1G5U5|T1G5U5_HELRO
Protein Wnt
Search

tr|T1G5U6|T1G5U6_HELRO
Uncharacterized protein
Search

0.24	Carboxylic ester hydrolase

0.36	GO:0097105	presynaptic membrane assembly
0.36	GO:0097104	postsynaptic membrane assembly
0.36	GO:0007158	neuron cell-cell adhesion
0.36	GO:0048488	synaptic vesicle endocytosis
0.35	GO:0050804	modulation of chemical synaptic transmission
0.34	GO:0043043	peptide biosynthetic process
0.34	GO:0006629	lipid metabolic process
0.33	GO:0044267	cellular protein metabolic process
0.33	GO:0010467	gene expression
0.33	GO:0009059	macromolecule biosynthetic process

0.45	GO:0016787	hydrolase activity
0.36	GO:0042043	neurexin family protein binding
0.34	GO:0003735	structural constituent of ribosome
0.34	GO:0004872	receptor activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.37	GO:0034719	SMN-Sm protein complex
0.34	GO:0009986	cell surface
0.34	GO:0045202	synapse
0.34	GO:0005576	extracellular region
0.34	GO:0005840	ribosome
0.34	GO:0005887	integral component of plasma membrane

0.45

GO:0016787

tr|T1G5U7|T1G5U7_HELRO
Uncharacterized protein
Search

0.68	Double C2-like domain-containing protein beta

0.63	GO:0017158	regulation of calcium ion-dependent exocytosis
0.58	GO:0007268	chemical synaptic transmission
0.57	GO:0051649	establishment of localization in cell
0.57	GO:0006887	exocytosis
0.53	GO:0034613	cellular protein localization
0.52	GO:0015031	protein transport
0.50	GO:0099643	signal release from synapse
0.49	GO:0097479	synaptic vesicle localization
0.49	GO:0099003	vesicle-mediated transport in synapse
0.48	GO:0006836	neurotransmitter transport

0.63	GO:0017137	Rab GTPase binding
0.62	GO:0005544	calcium-dependent phospholipid binding
0.54	GO:0005509	calcium ion binding
0.46	GO:0019905	syntaxin binding
0.44	GO:0030276	clathrin binding
0.34	GO:0004707	MAP kinase activity
0.32	GO:0042802	identical protein binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.57	GO:0098793	presynapse
0.55	GO:0070382	exocytic vesicle
0.39	GO:0030054	cell junction
0.39	GO:0005730	nucleolus
0.38	GO:0005886	plasma membrane
0.33	GO:0005783	endoplasmic reticulum
0.33	GO:0044232	organelle membrane contact site
0.33	GO:0005764	lysosome
0.33	GO:0030658	transport vesicle membrane
0.33	GO:0043005	neuron projection

0.34	EC:2.7.11.24	GO:0004707
0.34	KEGG:R00162	GO:0004707

tr|T1G5U8|T1G5U8_HELRO
Uncharacterized protein
Search

tr|T1G5U9|T1G5U9_HELRO
Lipase
Search

LIPA

0.46	Lysosomal acid lipase/cholesteryl ester hydrolase

0.49	GO:0006629	lipid metabolic process
0.43	GO:0034383	low-density lipoprotein particle clearance
0.43	GO:0048873	homeostasis of number of cells within a tissue
0.42	GO:0048771	tissue remodeling
0.42	GO:0001816	cytokine production
0.42	GO:0030324	lung development
0.41	GO:0006954	inflammatory response
0.41	GO:0008283	cell proliferation
0.40	GO:0000902	cell morphogenesis
0.40	GO:1901575	organic substance catabolic process

0.56

GO:0016788

hydrolase activity, acting on ester bonds

0.45	GO:0001650	fibrillar center
0.45	GO:0005764	lysosome
0.42	GO:0005775	vacuolar lumen
0.41	GO:0070062	extracellular exosome

0.56

EC:3.1

GO:0016788

tr|T1G5V0|T1G5V0_HELRO
Uncharacterized protein
Search

0.62	Putative 52 kDa repressor of the inhibitor of the protein kinase (Fragment)

0.56

GO:0016310

phosphorylation

0.68	GO:0046983	protein dimerization activity
0.59	GO:0016301	kinase activity

tr|T1G5V1|T1G5V1_HELRO
Uncharacterized protein
Search

0.48	Zinc finger protein 2

0.47	GO:0045665	negative regulation of neuron differentiation
0.45	GO:0043065	positive regulation of apoptotic process
0.43	GO:0006357	regulation of transcription by RNA polymerase II
0.43	GO:1900116	extracellular negative regulation of signal transduction
0.39	GO:1903507	negative regulation of nucleic acid-templated transcription
0.33	GO:0000413	protein peptidyl-prolyl isomerization
0.33	GO:0006457	protein folding
0.32	GO:0006351	transcription, DNA-templated
0.32	GO:0006520	cellular amino acid metabolic process

0.51	GO:0003676	nucleic acid binding
0.44	GO:0050682	AF-2 domain binding
0.43	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.43	GO:0048019	receptor antagonist activity
0.41	GO:0003714	transcription corepressor activity
0.39	GO:0008134	transcription factor binding
0.37	GO:0008270	zinc ion binding
0.33	GO:0004067	asparaginase activity
0.33	GO:0003755	peptidyl-prolyl cis-trans isomerase activity

0.42	GO:0005634	nucleus
0.38	GO:0005576	extracellular region
0.32	GO:0019013	viral nucleocapsid
0.32	GO:0043233	organelle lumen
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.32	GO:0043232	intracellular non-membrane-bounded organelle
0.31	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.33

EC:3.5.1.1

GO:0004067

tr|T1G5V2|T1G5V2_HELRO
Uncharacterized protein
Search

0.53	GO:0007416	synapse assembly
0.53	GO:0060007	linear vestibuloocular reflex
0.51	GO:0021562	vestibulocochlear nerve development
0.51	GO:0031223	auditory behavior
0.51	GO:0002093	auditory receptor cell morphogenesis
0.50	GO:0060384	innervation
0.50	GO:0001964	startle response
0.50	GO:0090102	cochlea development
0.50	GO:0051239	regulation of multicellular organismal process
0.49	GO:0002088	lens development in camera-type eye

0.47	GO:0098633	collagen fibril binding
0.44	GO:0005518	collagen binding
0.37	GO:0140096	catalytic activity, acting on a protein
0.36	GO:0016301	kinase activity
0.36	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.36	GO:0003725	double-stranded RNA binding
0.35	GO:0004888	transmembrane signaling receptor activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.50	GO:0009986	cell surface
0.46	GO:0005887	integral component of plasma membrane
0.41	GO:0031012	extracellular matrix
0.32	GO:0005622	intracellular

0.36

GO:0016773

tr|T1G5V3|T1G5V3_HELRO
Uncharacterized protein
Search

ENDOV

0.49	Endonuclease V

0.65	GO:0006281	DNA repair
0.64	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.38	GO:0016070	RNA metabolic process
0.35	GO:0009408	response to heat
0.35	GO:0006457	protein folding
0.33	GO:0006898	receptor-mediated endocytosis
0.33	GO:0016567	protein ubiquitination
0.32	GO:0006486	protein glycosylation
0.32	GO:0032259	methylation
0.32	GO:0010467	gene expression

0.66	GO:0004519	endonuclease activity
0.56	GO:0004536	deoxyribonuclease activity
0.52	GO:0000287	magnesium ion binding
0.45	GO:0003727	single-stranded RNA binding
0.43	GO:0004540	ribonuclease activity
0.38	GO:0003677	DNA binding
0.36	GO:0031072	heat shock protein binding
0.35	GO:0051082	unfolded protein binding
0.33	GO:0005044	scavenger receptor activity
0.33	GO:0032559	adenyl ribonucleotide binding

0.43	GO:0005730	nucleolus
0.42	GO:0005737	cytoplasm
0.32	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.32	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.32	EC:2.1.1.63	GO:0003908
0.33	KEGG:R03876	GO:0004842

tr|T1G5V4|T1G5V4_HELRO
Uncharacterized protein
Search

tr|T1G5V5|T1G5V5_HELRO
Uncharacterized protein
Search

0.46	GO:0043066	negative regulation of apoptotic process
0.41	GO:0006679	glucosylceramide biosynthetic process

0.65	GO:0016757	transferase activity, transferring glycosyl groups
0.37	GO:0003677	DNA binding
0.33	GO:0008270	zinc ion binding

0.45	GO:0000139	Golgi membrane
0.44	GO:0005789	endoplasmic reticulum membrane
0.39	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.65

GO:0016757

tr|T1G5V6|T1G5V6_HELRO
Uncharacterized protein
Search

0.59	Zinc finger MYM-type protein 1

0.36	GO:0006357	regulation of transcription by RNA polymerase II
0.35	GO:0007275	multicellular organism development
0.34	GO:0006796	phosphate-containing compound metabolic process
0.33	GO:0008299	isoprenoid biosynthetic process
0.33	GO:0072527	pyrimidine-containing compound metabolic process
0.33	GO:0006313	transposition, DNA-mediated
0.32	GO:0055086	nucleobase-containing small molecule metabolic process
0.32	GO:0019637	organophosphate metabolic process
0.32	GO:1901135	carbohydrate derivative metabolic process

0.68	GO:0046983	protein dimerization activity
0.37	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.34	GO:0003677	DNA binding
0.34	GO:0016301	kinase activity
0.34	GO:0019901	protein kinase binding
0.34	GO:0004170	dUTP diphosphatase activity
0.33	GO:0008270	zinc ion binding
0.33	GO:0004803	transposase activity

0.36	GO:0005654	nucleoplasm
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.34	EC:3.6.1.23	GO:0004170
0.34	KEGG:R02100	GO:0004170

tr|T1G5V7|T1G5V7_HELRO
Uncharacterized protein
Search

0.46

Tenascin

0.70	GO:0007596	blood coagulation
0.56	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.51	GO:0001775	cell activation
0.50	GO:0051258	protein polymerization
0.43	GO:0072376	protein activation cascade
0.43	GO:0007165	signal transduction
0.43	GO:0006357	regulation of transcription by RNA polymerase II
0.39	GO:0006351	transcription, DNA-templated

0.51	GO:0030674	protein binding, bridging
0.51	GO:0005509	calcium ion binding
0.48	GO:0005102	receptor binding
0.46	GO:0001104	RNA polymerase II transcription cofactor activity

0.55	GO:0005577	fibrinogen complex
0.45	GO:0016592	mediator complex
0.30	GO:0016020	membrane

tr|T1G5V8|T1G5V8_HELRO
Uncharacterized protein
Search

tr|T1G5V9|T1G5V9_HELRO
Uncharacterized protein
Search

tr|T1G5W0|T1G5W0_HELRO
Uncharacterized protein
Search

tr|T1G5W1|T1G5W1_HELRO
Uncharacterized protein
Search

tr|T1G5W2|T1G5W2_HELRO
Uncharacterized protein
Search

MGAT1

0.87	Mutant N-acetylglucosaminyltransferase I

0.74	GO:0043413	macromolecule glycosylation
0.74	GO:0009101	glycoprotein biosynthetic process
0.60	GO:0036211	protein modification process
0.56	GO:0044267	cellular protein metabolic process
0.52	GO:0006049	UDP-N-acetylglucosamine catabolic process
0.47	GO:0001701	in utero embryonic development
0.35	GO:0035283	central nervous system segmentation
0.35	GO:0035010	encapsulation of foreign target
0.35	GO:0016319	mushroom body development
0.34	GO:0008340	determination of adult lifespan

0.77	GO:0008375	acetylglucosaminyltransferase activity
0.42	GO:0140103	catalytic activity, acting on a glycoprotein
0.34	GO:0046872	metal ion binding
0.33	GO:0003924	GTPase activity
0.33	GO:0003676	nucleic acid binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.37	GO:0098791	Golgi subcompartment
0.36	GO:0098588	bounding membrane of organelle
0.36	GO:0070062	extracellular exosome
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.77

GO:0008375

tr|T1G5W3|T1G5W3_HELRO
Uncharacterized protein
Search

SAMHD1

0.93	SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1

0.71	GO:0006203	dGTP catabolic process
0.70	GO:0046061	dATP catabolic process
0.64	GO:0051289	protein homotetramerization
0.63	GO:0051607	defense response to virus
0.59	GO:0045088	regulation of innate immune response
0.54	GO:0090501	RNA phosphodiester bond hydrolysis
0.42	GO:0045087	innate immune response
0.38	GO:0044830	modulation by host of viral RNA genome replication
0.37	GO:1903901	negative regulation of viral life cycle
0.36	GO:0019221	cytokine-mediated signaling pathway

0.72	GO:0032560	guanyl deoxyribonucleotide binding
0.70	GO:0008832	dGTPase activity
0.56	GO:0042802	identical protein binding
0.54	GO:0004540	ribonuclease activity
0.51	GO:0008270	zinc ion binding
0.49	GO:0003723	RNA binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.54	GO:0005654	nucleoplasm
0.46	GO:0005886	plasma membrane
0.35	GO:0005667	transcription factor complex
0.30	GO:0016021	integral component of membrane

0.70	EC:3.1.5.1	GO:0008832
0.70	KEGG:R01856	GO:0008832

tr|T1G5W4|T1G5W4_HELRO
Uncharacterized protein
Search

0.55	GO:0055085	transmembrane transport
0.46	GO:0008643	carbohydrate transport
0.38	GO:0015992	proton transport
0.37	GO:0009624	response to nematode
0.32	GO:0055114	oxidation-reduction process

0.57	GO:0022857	transmembrane transporter activity
0.35	GO:0032440	2-alkenal reductase [NAD(P)] activity

0.38	GO:0009705	plant-type vacuole membrane
0.30	GO:0044425	membrane part

0.35

GO:0032440

tr|T1G5W5|T1G5W5_HELRO
Uncharacterized protein
Search

MED10

0.94	Mediator of RNA polymerase II transcription subunit 10

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.58	GO:0006351	transcription, DNA-templated
0.46	GO:0019827	stem cell population maintenance
0.43	GO:1905072	cardiac jelly development
0.43	GO:0007406	negative regulation of neuroblast proliferation
0.43	GO:0045893	positive regulation of transcription, DNA-templated
0.42	GO:0036302	atrioventricular canal development
0.35	GO:0016567	protein ubiquitination
0.32	GO:0006508	proteolysis
0.32	GO:0005975	carbohydrate metabolic process

0.79	GO:0001104	RNA polymerase II transcription cofactor activity
0.36	GO:0061630	ubiquitin protein ligase activity
0.34	GO:0004563	beta-N-acetylhexosaminidase activity
0.34	GO:0005515	protein binding
0.33	GO:0004222	metalloendopeptidase activity
0.33	GO:0046872	metal ion binding
0.33	GO:0003700	DNA binding transcription factor activity

0.77	GO:0016592	mediator complex
0.48	GO:0070847	core mediator complex
0.36	GO:0000151	ubiquitin ligase complex
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:3.2.1.52

GO:0004563

tr|T1G5W6|T1G5W6_HELRO
Uncharacterized protein
Search

0.58	GO:0007165	signal transduction
0.43	GO:0006629	lipid metabolic process
0.43	GO:0006915	apoptotic process
0.41	GO:0072659	protein localization to plasma membrane
0.40	GO:0016310	phosphorylation
0.40	GO:0006888	ER to Golgi vesicle-mediated transport
0.39	GO:0036211	protein modification process
0.39	GO:0098910	regulation of atrial cardiac muscle cell action potential
0.38	GO:0044267	cellular protein metabolic process
0.36	GO:0016569	covalent chromatin modification

0.47	GO:0008081	phosphoric diester hydrolase activity
0.44	GO:0030507	spectrin binding
0.42	GO:0008093	cytoskeletal adaptor activity
0.42	GO:0051117	ATPase binding
0.41	GO:0016301	kinase activity
0.40	GO:0140096	catalytic activity, acting on a protein
0.39	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.38	GO:0002039	p53 binding
0.37	GO:0016278	lysine N-methyltransferase activity
0.35	GO:0008270	zinc ion binding

0.43	GO:0014731	spectrin-associated cytoskeleton
0.39	GO:0043034	costamere
0.36	GO:0005694	chromosome
0.35	GO:0005886	plasma membrane
0.35	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.47

EC:3.1.4

GO:0008081

tr|T1G5W7|T1G5W7_HELRO
Uncharacterized protein
Search

tr|T1G5W8|T1G5W8_HELRO
Uncharacterized protein
Search

0.48	Low-density lipoprotein receptor

0.72	GO:0030509	BMP signaling pathway
0.70	GO:0060828	regulation of canonical Wnt signaling pathway
0.64	GO:0048513	animal organ development
0.54	GO:1901631	positive regulation of presynaptic membrane organization
0.52	GO:1904395	positive regulation of skeletal muscle acetylcholine-gated channel clustering
0.52	GO:0071340	skeletal muscle acetylcholine-gated channel clustering
0.52	GO:0097105	presynaptic membrane assembly
0.52	GO:0097104	postsynaptic membrane assembly
0.51	GO:0051124	synaptic growth at neuromuscular junction
0.50	GO:0050771	negative regulation of axonogenesis

0.69	GO:0005509	calcium ion binding
0.50	GO:0030971	receptor tyrosine kinase binding
0.45	GO:0042803	protein homodimerization activity
0.44	GO:0017147	Wnt-protein binding
0.44	GO:0042813	Wnt-activated receptor activity
0.39	GO:0097110	scaffold protein binding
0.38	GO:0034185	apolipoprotein binding
0.34	GO:0042393	histone binding
0.33	GO:0005041	low-density lipoprotein receptor activity
0.33	GO:0016887	ATPase activity

0.50	GO:0031594	neuromuscular junction
0.46	GO:0009986	cell surface
0.42	GO:0043235	receptor complex
0.40	GO:0005886	plasma membrane
0.39	GO:0014069	postsynaptic density
0.38	GO:0043025	neuronal cell body
0.38	GO:0030425	dendrite
0.38	GO:0098857	membrane microdomain
0.35	GO:0098796	membrane protein complex
0.34	GO:0016514	SWI/SNF complex

0.33

GO:0016887

tr|T1G5W9|T1G5W9_HELRO
Uncharacterized protein
Search

0.58	GO:0008643	carbohydrate transport
0.55	GO:0055085	transmembrane transport
0.44	GO:0048085	adult chitin-containing cuticle pigmentation
0.43	GO:0090277	positive regulation of peptide hormone secretion
0.42	GO:0042593	glucose homeostasis
0.35	GO:0071332	cellular response to fructose stimulus
0.35	GO:0003044	regulation of systemic arterial blood pressure mediated by a chemical signal
0.34	GO:0098657	import into cell
0.32	GO:0055114	oxidation-reduction process
0.32	GO:0015992	proton transport

0.57	GO:0022857	transmembrane transporter activity
0.35	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.32	GO:0008168	methyltransferase activity

0.34	GO:0016324	apical plasma membrane
0.33	GO:0005887	integral component of plasma membrane

0.35

GO:0032440

tr|T1G5X0|T1G5X0_HELRO
Uncharacterized protein
Search

0.90	CAP, cysteine-rich secretory protein, antigen 5

0.36	GO:0007339	binding of sperm to zona pellucida
0.35	GO:0043086	negative regulation of catalytic activity
0.35	GO:0032269	negative regulation of cellular protein metabolic process
0.35	GO:0052547	regulation of peptidase activity
0.34	GO:0007050	cell cycle arrest
0.34	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.34	GO:0071900	regulation of protein serine/threonine kinase activity
0.33	GO:0006508	proteolysis
0.33	GO:0042326	negative regulation of phosphorylation

0.36	GO:0004857	enzyme inhibitor activity
0.35	GO:0061134	peptidase regulator activity
0.34	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity
0.34	GO:0003924	GTPase activity
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0019001	guanyl nucleotide binding
0.34	GO:0008233	peptidase activity
0.33	GO:0005509	calcium ion binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.66	GO:0005576	extracellular region
0.37	GO:0097224	sperm connecting piece
0.36	GO:0001669	acrosomal vesicle
0.34	GO:0045121	membrane raft
0.33	GO:0005634	nucleus
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0016538

tr|T1G5X1|T1G5X1_HELRO
Uncharacterized protein
Search

0.44	Defense-related protein containing SCP domain

0.47	GO:0060325	face morphogenesis
0.45	GO:0030198	extracellular matrix organization
0.35	GO:0048513	animal organ development
0.35	GO:0060021	palate development
0.35	GO:1904888	cranial skeletal system development
0.35	GO:0048706	embryonic skeletal system development
0.35	GO:0061448	connective tissue development
0.34	GO:0060046	regulation of acrosome reaction
0.34	GO:0060541	respiratory system development
0.34	GO:0007339	binding of sperm to zona pellucida

0.45	GO:0008201	heparin binding
0.34	GO:0005246	calcium channel regulator activity
0.34	GO:0008233	peptidase activity
0.33	GO:0008061	chitin binding
0.33	GO:0050660	flavin adenine dinucleotide binding

0.66	GO:0005576	extracellular region
0.43	GO:0030133	transport vesicle
0.34	GO:1904813	ficolin-1-rich granule lumen
0.34	GO:0034774	secretory granule lumen
0.32	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016020	membrane

0.34

GO:0008233

tr|T1G5X2|T1G5X2_HELRO
Uncharacterized protein
Search

tr|T1G5X3|T1G5X3_HELRO
Uncharacterized protein
Search

4CL2

0.36	AMP-dependent synthetase and ligase

0.42	GO:0008218	bioluminescence
0.36	GO:0001676	long-chain fatty acid metabolic process
0.34	GO:0009698	phenylpropanoid metabolic process
0.33	GO:0046677	response to antibiotic
0.33	GO:0055114	oxidation-reduction process
0.32	GO:0006633	fatty acid biosynthetic process
0.32	GO:0070394	lipoteichoic acid metabolic process
0.32	GO:0019350	teichoic acid biosynthetic process

0.51	GO:0016874	ligase activity
0.37	GO:0047077	Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activity
0.34	GO:0031177	phosphopantetheine binding
0.33	GO:0051087	chaperone binding
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.32	GO:0046872	metal ion binding

0.33	GO:0005777	peroxisome
0.30	GO:0016021	integral component of membrane

0.51

GO:0016874

tr|T1G5X4|T1G5X4_HELRO
Uncharacterized protein
Search

0.30

GO:0044425

membrane part

tr|T1G5X5|T1G5X5_HELRO
Uncharacterized protein
Search

tr|T1G5X6|T1G5X6_HELRO
Uncharacterized protein
Search

tr|T1G5X7|T1G5X7_HELRO
Mitogen-activated protein kinase
Search

0.49	Mitogen-activated protein kinase

0.78	GO:0000165	MAPK cascade
0.38	GO:0060255	regulation of macromolecule metabolic process
0.37	GO:0046777	protein autophosphorylation
0.37	GO:0032846	positive regulation of homeostatic process
0.37	GO:2001252	positive regulation of chromosome organization
0.36	GO:0051347	positive regulation of transferase activity
0.36	GO:0009893	positive regulation of metabolic process
0.35	GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity
0.35	GO:0044671	sorocarp spore cell differentiation
0.35	GO:0043326	chemotaxis to folate

0.80	GO:0004707	MAP kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding

0.45	GO:0005622	intracellular
0.37	GO:0043227	membrane-bounded organelle
0.30	GO:0016020	membrane

0.80	EC:2.7.11.24	GO:0004707
0.80	KEGG:R00162	GO:0004707

tr|T1G5X8|T1G5X8_HELRO
Uncharacterized protein
Search

0.64	Cyclin and CBS domain divalent metal cation transport mediator 4b

0.35	GO:0050801	ion homeostasis
0.34	GO:0070166	enamel mineralization
0.34	GO:0055082	cellular chemical homeostasis
0.33	GO:1903830	magnesium ion transmembrane transport
0.33	GO:0035725	sodium ion transmembrane transport

0.33	GO:0015095	magnesium ion transmembrane transporter activity
0.33	GO:0015081	sodium ion transmembrane transporter activity

0.34	GO:0016323	basolateral plasma membrane
0.32	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

tr|T1G5X9|T1G5X9_HELRO
Uncharacterized protein
Search

0.10	Bromodomain and PHD finger-containing protein

0.42	GO:0016573	histone acetylation
0.33	GO:0034968	histone lysine methylation

0.54	GO:0046872	metal ion binding
0.41	GO:0003676	nucleic acid binding
0.38	GO:0042393	histone binding
0.36	GO:0140034	methylation-dependent protein binding
0.33	GO:0004402	histone acetyltransferase activity
0.33	GO:0018024	histone-lysine N-methyltransferase activity

0.43	GO:0070775	H3 histone acetyltransferase complex
0.36	GO:0016607	nuclear speck
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0004402

tr|T1G5Y0|T1G5Y0_HELRO
Uncharacterized protein
Search

0.40	GO:0006357	regulation of transcription by RNA polymerase II
0.34	GO:0046854	phosphatidylinositol phosphorylation

0.68	GO:0046983	protein dimerization activity
0.40	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.36	GO:0003677	DNA binding
0.34	GO:0016307	phosphatidylinositol phosphate kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.40	GO:0005654	nucleoplasm
0.35	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0016307

tr|T1G5Y1|T1G5Y1_HELRO
Uncharacterized protein
Search

0.53	AMP dependent coa ligase

0.39	GO:0008218	bioluminescence
0.39	GO:0001676	long-chain fatty acid metabolic process
0.37	GO:0019433	triglyceride catabolic process
0.37	GO:0046949	fatty-acyl-CoA biosynthetic process
0.33	GO:0009698	phenylpropanoid metabolic process
0.32	GO:0046677	response to antibiotic
0.32	GO:0006820	anion transport
0.32	GO:0055114	oxidation-reduction process

0.55	GO:0016874	ligase activity
0.34	GO:0047077	Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activity
0.33	GO:0051087	chaperone binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0046872	metal ion binding
0.32	GO:0016773	phosphotransferase activity, alcohol group as acceptor

0.34	GO:0005739	mitochondrion
0.33	GO:0005777	peroxisome
0.30	GO:0016020	membrane

0.55

GO:0016874

tr|T1G5Y2|T1G5Y2_HELRO
Uncharacterized protein
Search

TOP1

0.43	Topoisomerase I beta

0.72	GO:0006265	DNA topological change
0.53	GO:0040016	embryonic cleavage
0.52	GO:0032922	circadian regulation of gene expression
0.50	GO:0006338	chromatin remodeling
0.49	GO:0018105	peptidyl-serine phosphorylation
0.45	GO:0042493	response to drug
0.45	GO:0006260	DNA replication
0.42	GO:0007059	chromosome segregation
0.35	GO:0071373	cellular response to luteinizing hormone stimulus
0.35	GO:0012501	programmed cell death

0.77	GO:0003917	DNA topoisomerase type I activity
0.55	GO:0003677	DNA binding
0.49	GO:0003682	chromatin binding
0.48	GO:0001067	regulatory region nucleic acid binding
0.47	GO:0019904	protein domain specific binding
0.45	GO:0004674	protein serine/threonine kinase activity
0.39	GO:0032559	adenyl ribonucleotide binding
0.39	GO:0008144	drug binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0061505	DNA topoisomerase II activity

0.68	GO:0005694	chromosome
0.52	GO:0009330	DNA topoisomerase complex (ATP-hydrolyzing)
0.51	GO:0043204	perikaryon
0.50	GO:0001650	fibrillar center
0.49	GO:0000932	P-body
0.46	GO:0032993	protein-DNA complex
0.46	GO:0005654	nucleoplasm
0.35	GO:0001651	dense fibrillar component
0.34	GO:0000221	vacuolar proton-transporting V-type ATPase, V1 domain
0.34	GO:0042645	mitochondrial nucleoid

0.77

EC:5.99.1.2

GO:0003917

tr|T1G5Y3|T1G5Y3_HELRO
GPI mannosyltransferase 2
Search

0.47	GPI mannosyltransferase 2

0.78	GO:0006506	GPI anchor biosynthetic process
0.78	GO:0097502	mannosylation
0.45	GO:0045052	protein insertion into ER membrane by GPI attachment sequence
0.44	GO:0045313	rhabdomere membrane biogenesis
0.33	GO:0010952	positive regulation of peptidase activity

0.83	GO:0004584	dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity
0.33	GO:0070577	lysine-acetylated histone binding
0.33	GO:0016504	peptidase activator activity
0.33	GO:0070628	proteasome binding
0.32	GO:0016787	hydrolase activity

0.71	GO:0005789	endoplasmic reticulum membrane
0.43	GO:0031501	mannosyltransferase complex
0.30	GO:0031224	intrinsic component of membrane

0.83

EC:2.4.1.130

GO:0004584

tr|T1G5Y4|T1G5Y4_HELRO
Uncharacterized protein
Search

tr|T1G5Y5|T1G5Y5_HELRO
Uncharacterized protein
Search

0.62	GO:0008088	axo-dendritic transport
0.45	GO:0007411	axon guidance
0.44	GO:0000724	double-strand break repair via homologous recombination
0.40	GO:0015031	protein transport

0.62

GO:0019894

kinesin binding

0.60	GO:0043005	neuron projection
0.45	GO:0030915	Smc5-Smc6 complex
0.44	GO:0005744	mitochondrial inner membrane presequence translocase complex
0.30	GO:0031224	intrinsic component of membrane

tr|T1G5Y6|T1G5Y6_HELRO
Uncharacterized protein
Search

tr|T1G5Y7|T1G5Y7_HELRO
Uncharacterized protein
Search

tr|T1G5Y8|T1G5Y8_HELRO
Uncharacterized protein
Search

tr|T1G5Y9|T1G5Y9_HELRO
Uncharacterized protein
Search

0.48	GO:0019722	calcium-mediated signaling
0.47	GO:0003073	regulation of systemic arterial blood pressure
0.37	GO:1905949	negative regulation of calcium ion import across plasma membrane
0.36	GO:0042327	positive regulation of phosphorylation
0.35	GO:0043085	positive regulation of catalytic activity
0.34	GO:0009966	regulation of signal transduction
0.33	GO:0016192	vesicle-mediated transport
0.32	GO:0055085	transmembrane transport
0.32	GO:0055114	oxidation-reduction process

0.70	GO:0005509	calcium ion binding
0.46	GO:0030276	clathrin binding
0.44	GO:0015631	tubulin binding
0.44	GO:0003779	actin binding
0.37	GO:0098744	1-phosphatidylinositol 4-kinase activator activity
0.34	GO:0016174	NAD(P)H oxidase activity
0.33	GO:0015276	ligand-gated ion channel activity

0.35	GO:0005622	intracellular
0.35	GO:0098588	bounding membrane of organelle
0.35	GO:0012505	endomembrane system
0.34	GO:0070062	extracellular exosome
0.33	GO:0005886	plasma membrane
0.33	GO:0012506	vesicle membrane
0.33	GO:0048475	coated membrane
0.33	GO:0098805	whole membrane
0.32	GO:0098796	membrane protein complex
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:1.6.3.1

GO:0016174

tr|T1G5Z0|T1G5Z0_HELRO
Uncharacterized protein
Search

0.32	Carboxylic ester hydrolase (Fragment)

0.56	GO:0050808	synapse organization
0.55	GO:0050804	modulation of chemical synaptic transmission
0.51	GO:0007155	cell adhesion
0.39	GO:0048488	synaptic vesicle endocytosis
0.38	GO:0071709	membrane assembly
0.38	GO:0007399	nervous system development
0.36	GO:0071625	vocalization behavior
0.36	GO:0035176	social behavior
0.36	GO:0043113	receptor clustering
0.36	GO:0007612	learning

0.67	GO:0042043	neurexin family protein binding
0.44	GO:0004104	cholinesterase activity
0.36	GO:0097110	scaffold protein binding
0.36	GO:0004872	receptor activity
0.32	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.53	GO:0045202	synapse
0.48	GO:0005887	integral component of plasma membrane
0.38	GO:0009986	cell surface
0.35	GO:0030425	dendrite
0.35	GO:0030424	axon

0.44

EC:3.1.1.8

GO:0004104

tr|T1G5Z1|T1G5Z1_HELRO
Uncharacterized protein
Search

SPAST

0.53

Spastin

0.64	GO:0031117	positive regulation of microtubule depolymerization
0.61	GO:0034214	protein hexamerization
0.61	GO:0051013	microtubule severing
0.50	GO:0007409	axonogenesis
0.47	GO:0006888	ER to Golgi vesicle-mediated transport
0.46	GO:0032506	cytokinetic process
0.43	GO:0045773	positive regulation of axon extension
0.43	GO:0010256	endomembrane system organization
0.42	GO:1990138	neuron projection extension
0.42	GO:0021954	central nervous system neuron development

0.61	GO:0008568	microtubule-severing ATPase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0008017	microtubule binding
0.39	GO:0043014	alpha-tubulin binding
0.39	GO:0048487	beta-tubulin binding
0.34	GO:0004672	protein kinase activity
0.33	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen

0.54	GO:0005813	centrosome
0.54	GO:0005819	spindle
0.52	GO:0005874	microtubule
0.48	GO:0048471	perinuclear region of cytoplasm
0.44	GO:0005634	nucleus
0.39	GO:1904115	axon cytoplasm
0.39	GO:0030496	midbody
0.36	GO:0005768	endosome
0.36	GO:0005783	endoplasmic reticulum
0.35	GO:0031967	organelle envelope

0.61

EC:3.6.4.3

GO:0008568

tr|T1G5Z2|T1G5Z2_HELRO
Uncharacterized protein
Search

0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.61	GO:0035556	intracellular signal transduction
0.44	GO:0043547	positive regulation of GTPase activity
0.38	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.35	GO:0009968	negative regulation of signal transduction

0.63	GO:0004871	signal transducer activity
0.54	GO:0031681	G-protein beta-subunit binding
0.44	GO:0005096	GTPase activator activity

0.81	GO:1905360	GTPase complex
0.79	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.65	GO:0098797	plasma membrane protein complex
0.41	GO:0001917	photoreceptor inner segment
0.40	GO:0001750	photoreceptor outer segment
0.36	GO:0005737	cytoplasm
0.35	GO:0044292	dendrite terminus
0.30	GO:0016021	integral component of membrane

tr|T1G5Z3|T1G5Z3_HELRO
Uncharacterized protein
Search

METTL23

0.71	Methyltransferase like 23

0.60	GO:0032259	methylation
0.49	GO:0008213	protein alkylation
0.42	GO:0050890	cognition
0.41	GO:0016310	phosphorylation
0.41	GO:0045944	positive regulation of transcription by RNA polymerase II
0.39	GO:0018205	peptidyl-lysine modification

0.61	GO:0008168	methyltransferase activity
0.43	GO:0140096	catalytic activity, acting on a protein
0.42	GO:0016301	kinase activity
0.41	GO:0031072	heat shock protein binding
0.40	GO:0008134	transcription factor binding
0.35	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.42	GO:0005840	ribosome
0.37	GO:0005634	nucleus
0.37	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.61

GO:0008168

tr|T1G5Z4|T1G5Z4_HELRO
Uncharacterized protein
Search

STOM

0.67	Erythrocyte band 7 integral membrane protein isoform a

0.49	GO:1901585	regulation of acid-sensing ion channel activity
0.47	GO:0044829	positive regulation by host of viral genome replication
0.47	GO:0090314	positive regulation of protein targeting to membrane
0.44	GO:0051260	protein homooligomerization
0.37	GO:1905792	positive regulation of mechanosensory behavior
0.37	GO:1905789	positive regulation of detection of mechanical stimulus involved in sensory perception of touch
0.36	GO:0050976	detection of mechanical stimulus involved in sensory perception of touch
0.36	GO:0007638	mechanosensory behavior
0.34	GO:0043312	neutrophil degranulation

0.44	GO:0070063	RNA polymerase binding
0.43	GO:0042803	protein homodimerization activity
0.36	GO:0015485	cholesterol binding

0.47	GO:0005887	integral component of plasma membrane
0.45	GO:0045121	membrane raft
0.44	GO:0048471	perinuclear region of cytoplasm
0.42	GO:0005783	endoplasmic reticulum
0.41	GO:0005856	cytoskeleton
0.39	GO:0005739	mitochondrion
0.36	GO:0032589	neuron projection membrane
0.35	GO:0035579	specific granule membrane
0.35	GO:0035577	azurophil granule membrane
0.34	GO:0070821	tertiary granule membrane

tr|T1G5Z5|T1G5Z5_HELRO
Uncharacterized protein
Search

MAX

0.63	MYC associated factor X

0.44	GO:2001141	regulation of RNA biosynthetic process
0.44	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.44	GO:0010468	regulation of gene expression
0.36	GO:0051253	negative regulation of RNA metabolic process
0.36	GO:0010558	negative regulation of macromolecule biosynthetic process
0.36	GO:0031327	negative regulation of cellular biosynthetic process
0.35	GO:0070317	negative regulation of G0 to G1 transition
0.34	GO:0048678	response to axon injury
0.34	GO:0051402	neuron apoptotic process
0.34	GO:0032868	response to insulin

0.68	GO:0046983	protein dimerization activity
0.47	GO:0003700	DNA binding transcription factor activity
0.38	GO:0070888	E-box binding
0.36	GO:0042802	identical protein binding
0.34	GO:0003713	transcription coactivator activity
0.34	GO:0032403	protein complex binding

0.82	GO:0071339	MLL1 complex
0.77	GO:0090575	RNA polymerase II transcription factor complex
0.37	GO:0000790	nuclear chromatin
0.36	GO:0032993	protein-DNA complex
0.34	GO:0016605	PML body
0.34	GO:0030425	dendrite
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|T1G5Z6|T1G5Z6_HELRO
Uncharacterized protein
Search

0.42	GO:0016567	protein ubiquitination
0.37	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing
0.36	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.36	GO:0006508	proteolysis
0.36	GO:0000724	double-strand break repair via homologous recombination

0.62	GO:0008270	zinc ion binding
0.54	GO:0016874	ligase activity
0.43	GO:0004842	ubiquitin-protein transferase activity
0.40	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.39	GO:0003676	nucleic acid binding
0.39	GO:0061659	ubiquitin-like protein ligase activity
0.37	GO:0031624	ubiquitin conjugating enzyme binding
0.36	GO:0019901	protein kinase binding

0.37	GO:0005769	early endosome
0.37	GO:0000151	ubiquitin ligase complex
0.36	GO:0035861	site of double-strand break
0.34	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.54	EC:6	GO:0016874
0.43	KEGG:R03876	GO:0004842

tr|T1G5Z7|T1G5Z7_HELRO
Uncharacterized protein
Search

0.57	GO:0030421	defecation
0.55	GO:0007622	rhythmic behavior

0.35

GO:0016740

transferase activity

0.30

GO:0044425

membrane part

0.35

GO:0016740

tr|T1G5Z8|T1G5Z8_HELRO
Uncharacterized protein
Search

0.61	GO:0006508	proteolysis
0.39	GO:0006030	chitin metabolic process
0.39	GO:0007596	blood coagulation
0.37	GO:0006898	receptor-mediated endocytosis
0.34	GO:0006883	cellular sodium ion homeostasis
0.34	GO:0007605	sensory perception of sound
0.33	GO:0006955	immune response
0.33	GO:0065009	regulation of molecular function
0.32	GO:0016310	phosphorylation

0.69	GO:0004252	serine-type endopeptidase activity
0.39	GO:0005044	scavenger receptor activity
0.39	GO:0008061	chitin binding
0.36	GO:0005509	calcium ion binding
0.34	GO:0017080	sodium channel regulator activity
0.34	GO:0001871	pattern binding
0.33	GO:0008237	metallopeptidase activity
0.33	GO:0008270	zinc ion binding
0.33	GO:0030246	carbohydrate binding
0.33	GO:0004180	carboxypeptidase activity

0.38	GO:0005576	extracellular region
0.35	GO:0001669	acrosomal vesicle
0.34	GO:0043025	neuronal cell body
0.33	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

0.69

GO:0004252

tr|T1G5Z9|T1G5Z9_HELRO
Uncharacterized protein
Search

0.38	NADH dehydrogenase ubiquinone iron sulfur

0.53	GO:0055114	oxidation-reduction process
0.34	GO:0032981	mitochondrial respiratory chain complex I assembly
0.34	GO:0018108	peptidyl-tyrosine phosphorylation
0.33	GO:0007165	signal transduction
0.33	GO:0006119	oxidative phosphorylation

0.72	GO:0048038	quinone binding
0.69	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.67	GO:0051539	4 iron, 4 sulfur cluster binding
0.54	GO:0046872	metal ion binding
0.34	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.34	GO:0008901	ferredoxin hydrogenase activity
0.33	GO:0004930	G-protein coupled receptor activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding

0.41	GO:0005886	plasma membrane
0.35	GO:0005747	mitochondrial respiratory chain complex I
0.30	GO:0016021	integral component of membrane

0.69

GO:0008137

tr|T1G600|T1G600_HELRO
Uncharacterized protein
Search

0.61	GO:0006508	proteolysis
0.45	GO:0008219	cell death
0.40	GO:0019835	cytolysis
0.36	GO:0007313	maternal specification of dorsal/ventral axis, oocyte, soma encoded
0.35	GO:0007306	eggshell chorion assembly
0.35	GO:0007596	blood coagulation
0.35	GO:0002027	regulation of heart rate
0.34	GO:0071805	potassium ion transmembrane transport
0.34	GO:0006814	sodium ion transport

0.69	GO:0004252	serine-type endopeptidase activity
0.39	GO:0005509	calcium ion binding
0.35	GO:0030552	cAMP binding
0.34	GO:0005249	voltage-gated potassium channel activity
0.34	GO:0005515	protein binding

0.37	GO:0005576	extracellular region
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.69

GO:0004252

tr|T1G601|T1G601_HELRO
Uncharacterized protein
Search

0.74	RICS protein (Fragment)

0.61

GO:0007165

signal transduction

tr|T1G602|T1G602_HELRO
Uncharacterized protein
Search

0.48	Rhodopsin, GQ-coupled

0.76	GO:0007602	phototransduction
0.75	GO:0007601	visual perception
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.67	GO:0018298	protein-chromophore linkage
0.40	GO:0009584	detection of visible light
0.40	GO:0016037	light absorption
0.38	GO:0009589	detection of UV
0.37	GO:0034644	cellular response to UV
0.36	GO:0043052	thermotaxis
0.36	GO:0043153	entrainment of circadian clock by photoperiod

0.72	GO:0004930	G-protein coupled receptor activity
0.71	GO:0009881	photoreceptor activity
0.35	GO:0001653	peptide receptor activity
0.34	GO:0005503	all-trans retinal binding
0.34	GO:0005502	11-cis retinal binding

0.36	GO:0016028	rhabdomere
0.33	GO:0001750	photoreceptor outer segment
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1G603|T1G603_HELRO
Anion exchange protein
Search

0.58	Anion exchange protein (Fragment)

0.68	GO:0098656	anion transmembrane transport
0.68	GO:0015698	inorganic anion transport
0.45	GO:0030641	regulation of cellular pH
0.44	GO:0015701	bicarbonate transport
0.42	GO:0021860	pyramidal neuron development
0.42	GO:0035641	locomotory exploration behavior
0.41	GO:0048854	brain morphogenesis
0.41	GO:0035725	sodium ion transmembrane transport
0.41	GO:0035264	multicellular organism growth
0.40	GO:0009791	post-embryonic development

0.82	GO:0005452	inorganic anion exchanger activity
0.45	GO:0008510	sodium:bicarbonate symporter activity
0.44	GO:0015301	anion:anion antiporter activity
0.38	GO:0015108	chloride transmembrane transporter activity
0.32	GO:0003700	DNA binding transcription factor activity
0.32	GO:0003677	DNA binding

0.43	GO:0097441	basal dendrite
0.43	GO:0097442	CA3 pyramidal cell dendrite
0.42	GO:0097440	apical dendrite
0.42	GO:0043025	neuronal cell body
0.40	GO:0016323	basolateral plasma membrane
0.39	GO:0005887	integral component of plasma membrane
0.37	GO:0044298	cell body membrane
0.32	GO:0005634	nucleus

tr|T1G604|T1G604_HELRO
Uncharacterized protein
Search

PAK1

0.91	p21 protein-activated kinase 1 (Fragment)

0.78	GO:0060244	negative regulation of cell proliferation involved in contact inhibition
0.77	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway
0.75	GO:0048012	hepatocyte growth factor receptor signaling pathway
0.74	GO:0051496	positive regulation of stress fiber assembly
0.73	GO:0043507	positive regulation of JUN kinase activity
0.72	GO:0031116	positive regulation of microtubule polymerization
0.72	GO:0033138	positive regulation of peptidyl-serine phosphorylation
0.71	GO:0048754	branching morphogenesis of an epithelial tube
0.69	GO:0046777	protein autophosphorylation
0.68	GO:0042060	wound healing

0.70	GO:0005518	collagen binding
0.70	GO:0004674	protein serine/threonine kinase activity
0.56	GO:0048365	Rac GTPase binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0042803	protein homodimerization activity

0.74	GO:0071437	invadopodium
0.71	GO:0001726	ruffle
0.65	GO:0005911	cell-cell junction
0.59	GO:0005829	cytosol
0.52	GO:0043234	protein complex
0.50	GO:0005886	plasma membrane

0.70

GO:0004674

tr|T1G605|T1G605_HELRO
Uncharacterized protein
Search

0.39	GO:0006357	regulation of transcription by RNA polymerase II
0.36	GO:0043065	positive regulation of apoptotic process
0.36	GO:0048523	negative regulation of cellular process
0.35	GO:0010558	negative regulation of macromolecule biosynthetic process
0.35	GO:0051172	negative regulation of nitrogen compound metabolic process
0.35	GO:0010629	negative regulation of gene expression
0.35	GO:0040034	regulation of development, heterochronic
0.35	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle
0.35	GO:0051961	negative regulation of nervous system development
0.34	GO:0045664	regulation of neuron differentiation

0.51	GO:0003676	nucleic acid binding
0.39	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.38	GO:0046872	metal ion binding
0.34	GO:0004003	ATP-dependent DNA helicase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.37	GO:0005634	nucleus
0.34	GO:0005925	focal adhesion
0.33	GO:0005829	cytosol
0.33	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

tr|T1G606|T1G606_HELRO
Uncharacterized protein
Search

0.69	GO:0051056	regulation of small GTPase mediated signal transduction
0.69	GO:0043547	positive regulation of GTPase activity

0.70

GO:0005096

GTPase activator activity

0.30

GO:0044425

membrane part

tr|T1G607|T1G607_HELRO
Uncharacterized protein
Search

0.50	Homeobox domain protein (Fragment)

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.53	GO:0007275	multicellular organism development
0.43	GO:0048337	positive regulation of mesodermal cell fate specification
0.43	GO:1902680	positive regulation of RNA biosynthetic process
0.39	GO:0010605	negative regulation of macromolecule metabolic process
0.38	GO:0040026	positive regulation of vulval development
0.38	GO:0050679	positive regulation of epithelial cell proliferation
0.38	GO:0007548	sex differentiation

0.64	GO:0043565	sequence-specific DNA binding
0.48	GO:0003700	DNA binding transcription factor activity
0.40	GO:0044212	transcription regulatory region DNA binding
0.39	GO:0003690	double-stranded DNA binding
0.33	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.33	GO:0008083	growth factor activity
0.33	GO:0004000	adenosine deaminase activity
0.33	GO:0003887	DNA-directed DNA polymerase activity
0.33	GO:0004674	protein serine/threonine kinase activity
0.32	GO:0030554	adenyl nucleotide binding

0.61	GO:0005634	nucleus
0.38	GO:0005667	transcription factor complex
0.34	GO:0044446	intracellular organelle part
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.33

GO:0004715

tr|T1G608|T1G608_HELRO
Uncharacterized protein
Search

0.65	CCAAT binding transcription factor-B subunit

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.49	GO:1990830	cellular response to leukemia inhibitory factor
0.45	GO:1902680	positive regulation of RNA biosynthetic process
0.35	GO:0006351	transcription, DNA-templated
0.34	GO:0045540	regulation of cholesterol biosynthetic process
0.33	GO:0071897	DNA biosynthetic process

0.74	GO:0046982	protein heterodimerization activity
0.62	GO:0043565	sequence-specific DNA binding
0.49	GO:0070491	repressing transcription factor binding
0.49	GO:0035326	enhancer binding
0.46	GO:0001012	RNA polymerase II regulatory region DNA binding
0.44	GO:0003690	double-stranded DNA binding
0.41	GO:0003700	DNA binding transcription factor activity
0.36	GO:0032403	protein complex binding
0.33	GO:0003887	DNA-directed DNA polymerase activity

0.61	GO:0005634	nucleus
0.45	GO:0005667	transcription factor complex
0.44	GO:0032993	protein-DNA complex
0.40	GO:0044446	intracellular organelle part
0.34	GO:0043233	organelle lumen
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:2.7.7.7

GO:0003887

tr|T1G609|T1G609_HELRO
Uncharacterized protein
Search

tr|T1G610|T1G610_HELRO
Uncharacterized protein
Search

tr|T1G611|T1G611_HELRO
Uncharacterized protein
Search

0.70	sperm-associated antigen 16 protein-like

0.46	GO:0016310	phosphorylation
0.44	GO:0036211	protein modification process
0.42	GO:0044267	cellular protein metabolic process
0.39	GO:0032995	regulation of fungal-type cell wall biogenesis
0.39	GO:0060733	regulation of eIF2 alpha phosphorylation by amino acid starvation
0.39	GO:0031954	positive regulation of protein autophosphorylation
0.38	GO:2001125	negative regulation of translational frameshifting
0.38	GO:0000747	conjugation with cellular fusion
0.38	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.38	GO:1902660	negative regulation of glucose mediated signaling pathway

0.47	GO:0016301	kinase activity
0.44	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.43	GO:0140096	catalytic activity, acting on a protein
0.42	GO:0030554	adenyl nucleotide binding
0.41	GO:0097367	carbohydrate derivative binding
0.41	GO:0043168	anion binding
0.41	GO:0008144	drug binding
0.39	GO:0005080	protein kinase C binding
0.38	GO:0001965	G-protein alpha-subunit binding
0.37	GO:0044877	macromolecular complex binding

0.45	GO:0005634	nucleus
0.40	GO:0031514	motile cilium
0.39	GO:0019013	viral nucleocapsid
0.38	GO:0030529	intracellular ribonucleoprotein complex
0.37	GO:0005829	cytosol
0.36	GO:0031461	cullin-RING ubiquitin ligase complex
0.35	GO:0043232	intracellular non-membrane-bounded organelle
0.34	GO:0044446	intracellular organelle part
0.34	GO:0031931	TORC1 complex
0.34	GO:0031932	TORC2 complex

0.44