Queries 20001 to 21000

GO:0004713

tr|T1G0A2|T1G0A2_HELRO
Uncharacterized protein
Search

0.77	GO:0048666	neuron development
0.63	GO:0035881	amacrine cell differentiation
0.59	GO:0045597	positive regulation of cell differentiation
0.56	GO:0045165	cell fate commitment
0.55	GO:0003312	pancreatic PP cell differentiation
0.55	GO:0060730	regulation of intestinal epithelial structure maintenance
0.55	GO:0006355	regulation of transcription, DNA-templated
0.55	GO:2000675	negative regulation of type B pancreatic cell apoptotic process
0.55	GO:0007263	nitric oxide mediated signal transduction
0.54	GO:0003310	pancreatic A cell differentiation

0.68	GO:0046983	protein dimerization activity
0.54	GO:0070888	E-box binding
0.53	GO:0001105	RNA polymerase II transcription coactivator activity
0.53	GO:0001102	RNA polymerase II activating transcription factor binding
0.51	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.49	GO:0003682	chromatin binding

0.56	GO:0005634	nucleus
0.48	GO:0005667	transcription factor complex
0.41	GO:0044446	intracellular organelle part
0.38	GO:0005737	cytoplasm
0.34	GO:0070013	intracellular organelle lumen

tr|T1G0A3|T1G0A3_HELRO
Uncharacterized protein
Search

0.10	Ankyrin repeat and LEM domain-containing protein

0.63	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.44	GO:0070197	meiotic attachment of telomere to nuclear envelope
0.44	GO:0006998	nuclear envelope organization
0.36	GO:0016311	dephosphorylation

0.65	GO:0004519	endonuclease activity
0.43	GO:0031490	chromatin DNA binding
0.38	GO:0004035	alkaline phosphatase activity
0.35	GO:0035091	phosphatidylinositol binding
0.34	GO:0016874	ligase activity

0.43	GO:0031229	intrinsic component of nuclear inner membrane
0.42	GO:0031301	integral component of organelle membrane
0.35	GO:1905369	endopeptidase complex
0.34	GO:0043234	protein complex

0.38

EC:3.1.3.1

GO:0004035

tr|T1G0A4|T1G0A4_HELRO
Uncharacterized protein
Search

XPO7

0.90	Putative nuclear transport receptor ranbp16 importin beta superfamily

0.67	GO:0006886	intracellular protein transport
0.55	GO:0006611	protein export from nucleus
0.36	GO:0051028	mRNA transport

0.78	GO:0008536	Ran GTPase binding
0.56	GO:0005049	nuclear export signal receptor activity

0.56	GO:0005634	nucleus
0.47	GO:0012505	endomembrane system
0.45	GO:0031967	organelle envelope
0.44	GO:0043234	protein complex
0.39	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

tr|T1G0A5|T1G0A5_HELRO
Uncharacterized protein
Search

0.11	Dual specificity protein phosphatase 3

0.72	GO:0006470	protein dephosphorylation
0.39	GO:0000188	inactivation of MAPK activity
0.34	GO:0055114	oxidation-reduction process

0.79	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.70	GO:0004725	protein tyrosine phosphatase activity
0.39	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
0.39	GO:0033549	MAP kinase phosphatase activity
0.38	GO:0003995	acyl-CoA dehydrogenase activity
0.38	GO:0051015	actin filament binding
0.37	GO:0050660	flavin adenine dinucleotide binding

0.30

GO:0016020

membrane

0.79	EC:3.1.3	GO:0008138
0.39	KEGG:R04404	GO:0004439

tr|T1G0A6|T1G0A6_HELRO
Uncharacterized protein
Search

BPNT1

0.52	Pap-inositol-1,4-phosphatase

0.75	GO:0046854	phosphatidylinositol phosphorylation
0.35	GO:0016311	dephosphorylation
0.32	GO:0006508	proteolysis

0.37	GO:0008441	3'(2'),5'-bisphosphate nucleotidase activity
0.33	GO:0004222	metalloendopeptidase activity
0.32	GO:0046872	metal ion binding

0.30

GO:0031224

intrinsic component of membrane

0.37

EC:3.1.3.7

GO:0008441

tr|T1G0A7|T1G0A7_HELRO
RNA-binding protein 8A
Search

0.89	RNA-binding protein 8A

0.76	GO:0051028	mRNA transport
0.73	GO:0008380	RNA splicing
0.69	GO:0006397	mRNA processing
0.44	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.43	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.42	GO:0006338	chromatin remodeling
0.37	GO:0006417	regulation of translation
0.36	GO:0046595	establishment of pole plasm mRNA localization
0.35	GO:0051663	oocyte nucleus localization involved in oocyte dorsal/ventral axis specification
0.35	GO:0000335	negative regulation of transposition, DNA-mediated

0.76	GO:0003729	mRNA binding
0.35	GO:0008488	gamma-glutamyl carboxylase activity
0.34	GO:0051920	peroxiredoxin activity
0.33	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.33	GO:0005515	protein binding
0.33	GO:0016788	hydrolase activity, acting on ester bonds
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.80	GO:0016607	nuclear speck
0.49	GO:0005737	cytoplasm
0.42	GO:0035145	exon-exon junction complex
0.41	GO:0000228	nuclear chromosome
0.34	GO:0071013	catalytic step 2 spliceosome
0.33	GO:0019013	viral nucleocapsid
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:4.1.1

GO:0008488

tr|T1G0A8|T1G0A8_HELRO
Uncharacterized protein
Search

TRUB

0.42	Putative accessory gland protein (Fragment)

0.72	GO:0001522	pseudouridine synthesis
0.63	GO:0006396	RNA processing

0.72	GO:0009982	pseudouridine synthase activity
0.59	GO:0003723	RNA binding

0.72

EC:5.4.99.12

GO:0009982

tr|T1G0A9|T1G0A9_HELRO
Uncharacterized protein
Search

tr|T1G0B0|T1G0B0_HELRO
Uncharacterized protein
Search

tr|T1G0B1|T1G0B1_HELRO
Uncharacterized protein
Search

0.75	Carbonyl reductase

0.50	GO:0055114	oxidation-reduction process
0.42	GO:0015991	ATP hydrolysis coupled proton transport
0.39	GO:0042376	phylloquinone catabolic process
0.38	GO:0050890	cognition
0.37	GO:0042373	vitamin K metabolic process
0.35	GO:1905344	prostaglandin catabolic process
0.35	GO:0001542	ovulation from ovarian follicle
0.35	GO:0033574	response to testosterone
0.35	GO:0034698	response to gonadotropin
0.35	GO:0032570	response to progesterone

0.51	GO:0016491	oxidoreductase activity
0.39	GO:0015078	hydrogen ion transmembrane transporter activity
0.38	GO:0070402	NADPH binding
0.34	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.41	GO:0033177	proton-transporting two-sector ATPase complex, proton-transporting domain
0.37	GO:0033176	proton-transporting V-type ATPase complex
0.36	GO:0005654	nucleoplasm
0.36	GO:0005829	cytosol
0.35	GO:0005615	extracellular space
0.35	GO:0005902	microvillus
0.34	GO:1903561	extracellular vesicle
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.51

GO:0016491

tr|T1G0B2|T1G0B2_HELRO
Uncharacterized protein
Search

0.55	Elongation factor Ts, mitochondrial

0.59	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.36	GO:0055114	oxidation-reduction process
0.35	GO:0070507	regulation of microtubule cytoskeleton organization
0.35	GO:0048666	neuron development
0.33	GO:0043624	cellular protein complex disassembly
0.33	GO:0036211	protein modification process

0.63	GO:0003735	structural constituent of ribosome
0.37	GO:0016491	oxidoreductase activity
0.36	GO:0019799	tubulin N-acetyltransferase activity
0.32	GO:0005515	protein binding

0.61	GO:0005840	ribosome
0.47	GO:0005759	mitochondrial matrix
0.47	GO:0030054	cell junction
0.44	GO:0005654	nucleoplasm
0.35	GO:0005905	clathrin-coated pit
0.35	GO:0030424	axon
0.35	GO:0005819	spindle
0.34	GO:0005874	microtubule
0.33	GO:0031966	mitochondrial membrane
0.33	GO:0019866	organelle inner membrane

0.37

GO:0016491

tr|T1G0B3|T1G0B3_HELRO
Uncharacterized protein
Search

0.60	GO:0007275	multicellular organism development
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.46	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.46	GO:0000904	cell morphogenesis involved in differentiation
0.45	GO:0120036	plasma membrane bounded cell projection organization
0.45	GO:0051254	positive regulation of RNA metabolic process
0.45	GO:0006366	transcription by RNA polymerase II
0.45	GO:0010557	positive regulation of macromolecule biosynthetic process

0.65	GO:0043565	sequence-specific DNA binding
0.54	GO:0003700	DNA binding transcription factor activity
0.46	GO:0001012	RNA polymerase II regulatory region DNA binding
0.44	GO:0003690	double-stranded DNA binding
0.34	GO:1904929	coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway
0.34	GO:0008190	eukaryotic initiation factor 4E binding
0.33	GO:0061630	ubiquitin protein ligase activity
0.33	GO:0046982	protein heterodimerization activity
0.33	GO:0004672	protein kinase activity
0.32	GO:0030554	adenyl nucleotide binding

0.61	GO:0005634	nucleus
0.48	GO:0030426	growth cone
0.40	GO:0043234	protein complex
0.33	GO:0005887	integral component of plasma membrane
0.32	GO:0005737	cytoplasm

tr|T1G0B4|T1G0B4_HELRO
Uncharacterized protein
Search

0.75	GO:0035335	peptidyl-tyrosine dephosphorylation
0.50	GO:0051463	negative regulation of cortisol secretion
0.50	GO:0060125	negative regulation of growth hormone secretion
0.49	GO:0061582	intestinal epithelial cell migration
0.49	GO:0033277	abortive mitotic cell cycle
0.49	GO:0036302	atrioventricular canal development
0.49	GO:2001275	positive regulation of glucose import in response to insulin stimulus
0.49	GO:0033629	negative regulation of cell adhesion mediated by integrin
0.48	GO:0060020	Bergmann glial cell differentiation
0.48	GO:0071364	cellular response to epidermal growth factor stimulus

0.75	GO:0004725	protein tyrosine phosphatase activity
0.48	GO:0005158	insulin receptor binding
0.48	GO:0051428	peptide hormone receptor binding
0.47	GO:0005070	SH3/SH2 adaptor activity
0.47	GO:0030971	receptor tyrosine kinase binding
0.45	GO:0050839	cell adhesion molecule binding
0.36	GO:0031748	D1 dopamine receptor binding
0.35	GO:0043274	phospholipase binding
0.35	GO:0043560	insulin receptor substrate binding
0.34	GO:0019904	protein domain specific binding

0.40	GO:0005634	nucleus
0.40	GO:0005737	cytoplasm
0.39	GO:0043234	protein complex
0.33	GO:0070013	intracellular organelle lumen
0.32	GO:0044446	intracellular organelle part
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.75	EC:3.1.3.48	GO:0004725
0.34	KEGG:R04545	GO:0046934

tr|T1G0B5|T1G0B5_HELRO
Uncharacterized protein
Search

BUD31

0.91	Putative g10 protein/ nuclear transcription regulator

0.53	GO:2000825	positive regulation of androgen receptor activity
0.48	GO:0000398	mRNA splicing, via spliceosome

0.50	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.50	GO:0035257	nuclear hormone receptor binding
0.33	GO:0003700	DNA binding transcription factor activity

0.61	GO:0005634	nucleus
0.45	GO:0000785	chromatin
0.44	GO:0031974	membrane-enclosed lumen
0.42	GO:0030529	intracellular ribonucleoprotein complex
0.41	GO:1902494	catalytic complex
0.34	GO:0120114	Sm-like protein family complex

tr|T1G0B6|T1G0B6_HELRO
Uncharacterized protein
Search

TMEM67

0.64	Transmembrane protein 67

0.85	GO:0010826	negative regulation of centrosome duplication
0.80	GO:0060271	cilium assembly
0.53	GO:0030433	ubiquitin-dependent ERAD pathway
0.43	GO:0060028	convergent extension involved in axis elongation
0.43	GO:0060027	convergent extension involved in gastrulation
0.42	GO:0003341	cilium movement
0.36	GO:0048754	branching morphogenesis of an epithelial tube
0.36	GO:0007368	determination of left/right symmetry
0.36	GO:0007507	heart development
0.35	GO:1902857	positive regulation of non-motile cilium assembly

0.56	GO:0031005	filamin binding
0.48	GO:0051082	unfolded protein binding
0.35	GO:0051787	misfolded protein binding
0.33	GO:0005044	scavenger receptor activity
0.33	GO:0004222	metalloendopeptidase activity
0.33	GO:0001871	pattern binding
0.33	GO:0019843	rRNA binding
0.33	GO:0003735	structural constituent of ribosome
0.33	GO:0004930	G-protein coupled receptor activity
0.32	GO:0008270	zinc ion binding

0.85	GO:0036038	MKS complex
0.54	GO:0060170	ciliary membrane
0.51	GO:0005813	centrosome
0.50	GO:0030659	cytoplasmic vesicle membrane
0.48	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0005930	axoneme
0.33	GO:0015935	small ribosomal subunit
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0004222

tr|T1G0B7|T1G0B7_HELRO
Uncharacterized protein
Search

0.38	GO:0035544	negative regulation of SNARE complex assembly
0.38	GO:0070647	protein modification by small protein conjugation or removal
0.35	GO:0046597	negative regulation of viral entry into host cell
0.34	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling
0.34	GO:0045087	innate immune response
0.34	GO:0060271	cilium assembly
0.34	GO:0006546	glycine catabolic process
0.33	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.33	GO:0006468	protein phosphorylation
0.33	GO:0006508	proteolysis

0.61	GO:0008270	zinc ion binding
0.43	GO:0016874	ligase activity
0.37	GO:0004842	ubiquitin-protein transferase activity
0.34	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.34	GO:0016642	oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor
0.34	GO:0061659	ubiquitin-like protein ligase activity
0.33	GO:0004521	endoribonuclease activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0005509	calcium ion binding
0.33	GO:0008144	drug binding

0.44	GO:0005622	intracellular
0.34	GO:0030992	intraciliary transport particle B
0.34	GO:0005929	cilium
0.33	GO:0012505	endomembrane system
0.32	GO:0043228	non-membrane-bounded organelle
0.32	GO:0044422	organelle part
0.32	GO:0043227	membrane-bounded organelle
0.30	GO:0016020	membrane

0.43	EC:6	GO:0016874
0.37	KEGG:R03876	GO:0004842

tr|T1G0B8|T1G0B8_HELRO
Bestrophin homolog
Search

0.62	Bestrophin

0.73	GO:1902476	chloride transmembrane transport
0.51	GO:0007601	visual perception
0.45	GO:0009992	cellular water homeostasis
0.39	GO:0050962	detection of light stimulus involved in sensory perception
0.38	GO:0030321	transepithelial chloride transport
0.38	GO:0051924	regulation of calcium ion transport
0.38	GO:0009584	detection of visible light
0.36	GO:0051899	membrane depolarization
0.35	GO:0007608	sensory perception of smell
0.33	GO:0006627	protein processing involved in protein targeting to mitochondrion

0.74	GO:0005254	chloride channel activity
0.45	GO:0005225	volume-sensitive anion channel activity
0.40	GO:0022839	ion gated channel activity
0.40	GO:0008381	mechanosensitive ion channel activity
0.36	GO:0042802	identical protein binding
0.33	GO:0004222	metalloendopeptidase activity
0.32	GO:0046872	metal ion binding

0.76	GO:0034707	chloride channel complex
0.53	GO:0005886	plasma membrane
0.35	GO:0005929	cilium
0.33	GO:0005759	mitochondrial matrix

0.33

GO:0004222

tr|T1G0B9|T1G0B9_HELRO
Uncharacterized protein
Search

0.75	GO:1900402	regulation of carbohydrate metabolic process by regulation of transcription from RNA polymerase II promoter
0.57	GO:0045944	positive regulation of transcription by RNA polymerase II
0.54	GO:0006366	transcription by RNA polymerase II
0.49	GO:0090324	negative regulation of oxidative phosphorylation
0.48	GO:0045821	positive regulation of glycolytic process
0.48	GO:0045723	positive regulation of fatty acid biosynthetic process
0.48	GO:0033137	negative regulation of peptidyl-serine phosphorylation
0.47	GO:0010255	glucose mediated signaling pathway
0.47	GO:0071157	negative regulation of cell cycle arrest
0.45	GO:0008284	positive regulation of cell proliferation

0.68	GO:0046983	protein dimerization activity
0.65	GO:0000989	transcription factor activity, transcription factor binding
0.58	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.56	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.46	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.45	GO:0000987	proximal promoter sequence-specific DNA binding
0.43	GO:0008134	transcription factor binding
0.37	GO:0019901	protein kinase binding
0.37	GO:0042802	identical protein binding

0.45	GO:0005634	nucleus
0.43	GO:0005667	transcription factor complex
0.42	GO:0005829	cytosol
0.38	GO:0043233	organelle lumen
0.37	GO:0005741	mitochondrial outer membrane

tr|T1G0C0|T1G0C0_HELRO
Uncharacterized protein
Search

0.63	TLC domain-containing protein 2

0.30

GO:0044425

membrane part

tr|T1G0C1|T1G0C1_HELRO
Uncharacterized protein
Search

0.10	Putative homeodomain transcription factor 1 (Fragment)

0.34	GO:0006003	fructose 2,6-bisphosphate metabolic process
0.34	GO:0006000	fructose metabolic process
0.33	GO:0046835	carbohydrate phosphorylation
0.33	GO:0006351	transcription, DNA-templated
0.33	GO:0006357	regulation of transcription by RNA polymerase II

0.48	GO:0003677	DNA binding
0.34	GO:0003873	6-phosphofructo-2-kinase activity
0.33	GO:0046983	protein dimerization activity
0.32	GO:0003700	DNA binding transcription factor activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.35	GO:0005783	endoplasmic reticulum
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.34	EC:2.7.1.105	GO:0003873
0.34	KEGG:R02732	GO:0003873

tr|T1G0C2|T1G0C2_HELRO
Uncharacterized protein
Search

0.44	Mannosyl-oligosaccharide glucosidase

0.72

GO:0009311

oligosaccharide metabolic process

0.83

GO:0004573

mannosyl-oligosaccharide glucosidase activity

0.35	GO:0012505	endomembrane system
0.30	GO:0031224	intrinsic component of membrane

0.83

EC:3.2.1.106

GO:0004573

tr|T1G0C3|T1G0C3_HELRO
Uncharacterized protein
Search

TMED4

0.84	Transmembrane emp24 domain-containing protein eca

0.37	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.34	GO:0033036	macromolecule localization
0.34	GO:0071702	organic substance transport
0.34	GO:0007165	signal transduction
0.34	GO:0042886	amide transport

0.34	GO:0004871	signal transducer activity
0.33	GO:0005319	lipid transporter activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003676	nucleic acid binding

0.66	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

tr|T1G0C4|T1G0C4_HELRO
Phosphodiesterase
Search

0.55	Phosphodiesterase

0.60	GO:0007165	signal transduction
0.46	GO:0006198	cAMP catabolic process
0.43	GO:0035690	cellular response to drug
0.42	GO:0043949	regulation of cAMP-mediated signaling
0.42	GO:0010738	regulation of protein kinase A signaling
0.41	GO:0032743	positive regulation of interleukin-2 production
0.41	GO:0030593	neutrophil chemotaxis
0.41	GO:0032729	positive regulation of interferon-gamma production
0.40	GO:0001780	neutrophil homeostasis
0.40	GO:0003008	system process

0.79	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.54	GO:0046872	metal ion binding
0.45	GO:0030552	cAMP binding
0.39	GO:0043015	gamma-tubulin binding
0.35	GO:0097110	scaffold protein binding
0.35	GO:0051117	ATPase binding
0.35	GO:0044325	ion channel binding
0.33	GO:0003924	GTPase activity
0.33	GO:0005525	GTP binding
0.33	GO:0008144	drug binding

0.41	GO:0005829	cytosol
0.40	GO:0048471	perinuclear region of cytoplasm
0.40	GO:0060076	excitatory synapse
0.40	GO:0120025	plasma membrane bounded cell projection
0.39	GO:0014069	postsynaptic density
0.39	GO:0005813	centrosome
0.39	GO:0000930	gamma-tubulin complex
0.39	GO:0008021	synaptic vesicle
0.39	GO:0036477	somatodendritic compartment
0.38	GO:0044428	nuclear part

0.79

GO:0004114

tr|T1G0C5|T1G0C5_HELRO
Uncharacterized protein
Search

tr|T1G0C6|T1G0C6_HELRO
Uncharacterized protein
Search

LHX3

0.75	Lim homeobox protein 3 splice variant

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.52	GO:0008045	motor neuron axon guidance
0.45	GO:0021526	medial motor column neuron differentiation
0.45	GO:0021521	ventral spinal cord interneuron specification
0.44	GO:0021527	spinal cord association neuron differentiation
0.44	GO:0021520	spinal cord motor neuron cell fate specification
0.43	GO:0021983	pituitary gland development
0.42	GO:0048839	inner ear development

0.65	GO:0043565	sequence-specific DNA binding
0.54	GO:0046872	metal ion binding
0.42	GO:0001085	RNA polymerase II transcription factor binding
0.42	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.41	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.41	GO:0001012	RNA polymerase II regulatory region DNA binding
0.40	GO:0003690	double-stranded DNA binding
0.32	GO:0016740	transferase activity

0.61	GO:0005634	nucleus
0.40	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

0.32

GO:0016740

tr|T1G0C7|T1G0C7_HELRO
Uncharacterized protein
Search

tr|T1G0C8|T1G0C8_HELRO
Uncharacterized protein
Search

ECT2

0.97	Epithelial cell transforming 2

0.82	GO:0045666	positive regulation of neuron differentiation
0.78	GO:0035023	regulation of Rho protein signal transduction
0.76	GO:0043547	positive regulation of GTPase activity
0.75	GO:0000902	cell morphogenesis
0.73	GO:0000910	cytokinesis
0.61	GO:0035556	intracellular signal transduction
0.53	GO:0070830	bicellular tight junction assembly
0.53	GO:0051988	regulation of attachment of spindle microtubules to kinetochore
0.52	GO:0071277	cellular response to calcium ion
0.52	GO:0071479	cellular response to ionizing radiation

0.78	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.76	GO:0005096	GTPase activator activity
0.48	GO:0042803	protein homodimerization activity
0.34	GO:0004871	signal transducer activity
0.32	GO:0016740	transferase activity

0.61	GO:0005634	nucleus
0.55	GO:0097149	centralspindlin complex
0.52	GO:0097610	cell surface furrow
0.51	GO:0030496	midbody
0.50	GO:0032155	cell division site part
0.50	GO:0005923	bicellular tight junction
0.49	GO:0005737	cytoplasm

0.32

GO:0016740

tr|T1G0C9|T1G0C9_HELRO
Uncharacterized protein
Search

0.69	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.50	GO:0030522	intracellular receptor signaling pathway
0.38	GO:0007538	primary sex determination
0.36	GO:0009888	tissue development
0.35	GO:1902680	positive regulation of RNA biosynthetic process
0.35	GO:1902679	negative regulation of RNA biosynthetic process

0.65	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.62	GO:0003707	steroid hormone receptor activity
0.61	GO:0003700	DNA binding transcription factor activity
0.37	GO:0044212	transcription regulatory region DNA binding
0.36	GO:0003690	double-stranded DNA binding
0.34	GO:0003682	chromatin binding

0.61	GO:0005634	nucleus
0.34	GO:0005667	transcription factor complex
0.33	GO:0044446	intracellular organelle part
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|T1G0D0|T1G0D0_HELRO
Uncharacterized protein
Search

tr|T1G0D1|T1G0D1_HELRO
Histone H3
Search

0.10	Histone superfamily protein

0.36

GO:0006334

nucleosome assembly

0.73	GO:0046982	protein heterodimerization activity
0.54	GO:0003677	DNA binding
0.37	GO:0031491	nucleosome binding

0.74	GO:0000786	nucleosome
0.60	GO:0005634	nucleus
0.37	GO:0010369	chromocenter
0.33	GO:0043233	organelle lumen

tr|T1G0D2|T1G0D2_HELRO
Uncharacterized protein
Search

PSIP1

0.63	PC4 and SFRS1-interacting protein (Fragment)

0.85	GO:0000395	mRNA 5'-splice site recognition
0.73	GO:0009408	response to heat
0.69	GO:0006979	response to oxidative stress
0.53	GO:0006366	transcription by RNA polymerase II
0.53	GO:0045944	positive regulation of transcription by RNA polymerase II
0.38	GO:0075713	establishment of integrated proviral latency
0.38	GO:0051169	nuclear transport

0.61	GO:0097100	supercoiled DNA binding
0.58	GO:0001105	RNA polymerase II transcription coactivator activity
0.58	GO:0033613	activating transcription factor binding
0.54	GO:0003682	chromatin binding
0.37	GO:0003723	RNA binding

0.67	GO:0031981	nuclear lumen
0.58	GO:0035327	transcriptionally active chromatin
0.56	GO:0000792	heterochromatin
0.36	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|T1G0D3|T1G0D3_HELRO
Histone H4
Search

0.61	GO:0006352	DNA-templated transcription, initiation
0.46	GO:0006334	nucleosome assembly

0.74	GO:0046982	protein heterodimerization activity
0.55	GO:0003677	DNA binding
0.34	GO:0042393	histone binding

0.75	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.33	GO:0031974	membrane-enclosed lumen

tr|T1G0D4|T1G0D4_HELRO
Uncharacterized protein
Search

CSNK1A1

0.74	Casein kinase I alpha S

0.63	GO:0006468	protein phosphorylation
0.48	GO:0018209	peptidyl-serine modification
0.46	GO:0045104	intermediate filament cytoskeleton organization
0.46	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.45	GO:0016055	Wnt signaling pathway
0.45	GO:1904424	regulation of GTP binding
0.44	GO:0006909	phagocytosis
0.43	GO:0007030	Golgi organization
0.40	GO:0008360	regulation of cell shape
0.40	GO:0048856	anatomical structure development

0.65	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0004610	phosphoacetylglucosamine mutase activity
0.35	GO:0005515	protein binding
0.34	GO:0042277	peptide binding
0.34	GO:0000287	magnesium ion binding

0.45	GO:0045095	keratin filament
0.45	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex
0.45	GO:0005815	microtubule organizing center
0.44	GO:0016607	nuclear speck
0.44	GO:0030877	beta-catenin destruction complex
0.43	GO:0044441	ciliary part
0.41	GO:0000777	condensed chromosome kinetochore
0.40	GO:0005829	cytosol
0.37	GO:0030529	intracellular ribonucleoprotein complex
0.35	GO:0000139	Golgi membrane

0.65	EC:2.7.11	GO:0004674
0.37	KEGG:R08193	GO:0004610

tr|T1G0D5|T1G0D5_HELRO
Uncharacterized protein
Search

0.85	GO:0006964	positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria
0.85	GO:0061057	peptidoglycan recognition protein signaling pathway
0.85	GO:0033160	positive regulation of protein import into nucleus, translocation
0.83	GO:0022416	chaeta development
0.82	GO:0070534	protein K63-linked ubiquitination
0.82	GO:0070936	protein K48-linked ubiquitination
0.80	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.79	GO:0050829	defense response to Gram-negative bacterium
0.78	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.73	GO:0006915	apoptotic process

0.85	GO:0089720	caspase binding
0.83	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.75	GO:0031625	ubiquitin protein ligase binding
0.72	GO:0061630	ubiquitin protein ligase activity
0.39	GO:0008270	zinc ion binding
0.39	GO:0016874	ligase activity

0.75	GO:0048471	perinuclear region of cytoplasm
0.46	GO:0005856	cytoskeleton
0.40	GO:0005829	cytosol
0.39	GO:0005634	nucleus

0.39

GO:0016874

tr|T1G0D6|T1G0D6_HELRO
Uncharacterized protein
Search

tr|T1G0D7|T1G0D7_HELRO
Transporter
Search

0.17	Transporter

0.75	GO:0006836	neurotransmitter transport
0.54	GO:0055085	transmembrane transport
0.44	GO:0006865	amino acid transport
0.42	GO:0015718	monocarboxylic acid transport
0.39	GO:0007268	chemical synaptic transmission
0.38	GO:0015893	drug transport
0.36	GO:0090493	catecholamine uptake
0.36	GO:0060092	regulation of synaptic transmission, glycinergic
0.36	GO:0006812	cation transport
0.36	GO:0001505	regulation of neurotransmitter levels

0.78	GO:0005328	neurotransmitter:sodium symporter activity
0.46	GO:0005343	organic acid:sodium symporter activity
0.45	GO:0015171	amino acid transmembrane transporter activity
0.45	GO:0015355	secondary active monocarboxylate transmembrane transporter activity
0.43	GO:0015296	anion:cation symporter activity
0.39	GO:0015238	drug transmembrane transporter activity
0.36	GO:0072349	modified amino acid transmembrane transporter activity
0.36	GO:0008504	monoamine transmembrane transporter activity
0.35	GO:0051184	cofactor transmembrane transporter activity
0.35	GO:1901618	organic hydroxy compound transmembrane transporter activity

0.45	GO:0005887	integral component of plasma membrane
0.38	GO:0097458	neuron part
0.37	GO:0044456	synapse part
0.36	GO:0120025	plasma membrane bounded cell projection

tr|T1G0D8|T1G0D8_HELRO
Uncharacterized protein
Search

DESI2

0.83	Desumoylating isopeptidase

0.50	GO:0060027	convergent extension involved in gastrulation
0.44	GO:0006508	proteolysis

0.44

GO:0008233

peptidase activity

0.48

GO:0005737

cytoplasm

0.44

GO:0008233

tr|T1G0D9|T1G0D9_HELRO
Uncharacterized protein
Search

0.10	High mobility group protein B1

0.36	GO:2001141	regulation of RNA biosynthetic process
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:0010468	regulation of gene expression
0.36	GO:0007275	multicellular organism development
0.34	GO:0007530	sex determination
0.34	GO:0007548	sex differentiation
0.33	GO:0030154	cell differentiation
0.32	GO:0006351	transcription, DNA-templated
0.32	GO:0055114	oxidation-reduction process

0.55	GO:0003677	DNA binding
0.36	GO:0003700	DNA binding transcription factor activity
0.34	GO:0005516	calmodulin binding
0.33	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.32	GO:0020037	heme binding
0.32	GO:0005506	iron ion binding

0.61	GO:0005634	nucleus
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.33

EC:1.14.14

GO:0016712

tr|T1G0E0|T1G0E0_HELRO
Uncharacterized protein
Search

0.57	Glucose-dependent insulinotropic receptor

0.36	GO:0070647	protein modification by small protein conjugation or removal
0.34	GO:0042073	intraciliary transport
0.34	GO:0060271	cilium assembly
0.33	GO:0006508	proteolysis
0.33	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:0006313	transposition, DNA-mediated
0.33	GO:0015074	DNA integration
0.33	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.33	GO:0016192	vesicle-mediated transport
0.32	GO:0006351	transcription, DNA-templated

0.35	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.34	GO:0004842	ubiquitin-protein transferase activity
0.34	GO:0031683	G-protein beta/gamma-subunit complex binding
0.33	GO:0015631	tubulin binding
0.33	GO:0003924	GTPase activity
0.33	GO:0043565	sequence-specific DNA binding
0.33	GO:0019001	guanyl nucleotide binding
0.33	GO:0008270	zinc ion binding
0.33	GO:0004871	signal transducer activity
0.33	GO:0000062	fatty-acyl-CoA binding

0.34	GO:0030992	intraciliary transport particle B
0.34	GO:0031514	motile cilium
0.33	GO:0030008	TRAPP complex
0.33	GO:0043231	intracellular membrane-bounded organelle
0.32	GO:0044444	cytoplasmic part
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.33	EC:3.6.1.31	GO:0004636
0.34	KEGG:R03876	GO:0004842

tr|T1G0E1|T1G0E1_HELRO
Fatty acyl-CoA reductase
Search

FAR1

0.55	Fatty acyl-CoA reductase

0.62	GO:0006629	lipid metabolic process
0.54	GO:0035336	long-chain fatty-acyl-CoA metabolic process
0.53	GO:0010025	wax biosynthetic process
0.52	GO:0055114	oxidation-reduction process
0.48	GO:0046504	glycerol ether biosynthetic process
0.40	GO:0090407	organophosphate biosynthetic process
0.38	GO:0006796	phosphate-containing compound metabolic process
0.37	GO:0008340	determination of adult lifespan
0.34	GO:0006508	proteolysis
0.32	GO:0010345	suberin biosynthetic process

0.83	GO:0080019	fatty-acyl-CoA reductase (alcohol-forming) activity
0.83	GO:0102965	alcohol-forming fatty acyl-CoA reductase activity
0.35	GO:0004252	serine-type endopeptidase activity
0.33	GO:0008374	O-acyltransferase activity
0.32	GO:0050062	long-chain-fatty-acyl-CoA reductase activity

0.50	GO:0005777	peroxisome
0.47	GO:0031903	microbody membrane
0.46	GO:0031301	integral component of organelle membrane
0.34	GO:0031907	microbody lumen

0.35

GO:0004252

tr|T1G0E2|T1G0E2_HELRO
Uncharacterized protein
Search

DHRS4

0.31	Short-chain dehydrogenase

0.51	GO:0055114	oxidation-reduction process
0.45	GO:0042574	retinal metabolic process
0.37	GO:0080024	indolebutyric acid metabolic process
0.37	GO:0080026	response to indolebutyric acid
0.37	GO:0051262	protein tetramerization
0.36	GO:0048767	root hair elongation
0.36	GO:0008202	steroid metabolic process
0.36	GO:0006066	alcohol metabolic process
0.36	GO:0042180	cellular ketone metabolic process
0.34	GO:0034754	cellular hormone metabolic process

0.53	GO:0016491	oxidoreductase activity
0.36	GO:0005102	receptor binding
0.33	GO:0004312	fatty acid synthase activity

0.44	GO:0005777	peroxisome
0.38	GO:0005739	mitochondrion
0.36	GO:0031903	microbody membrane
0.34	GO:0070062	extracellular exosome
0.33	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0005634	nucleus

0.53

GO:0016491

tr|T1G0E3|T1G0E3_HELRO
Uncharacterized protein
Search

KIFAP3

0.93	Kinesin associated protein 3

0.57	GO:0046587	positive regulation of calcium-dependent cell-cell adhesion
0.50	GO:0008285	negative regulation of cell proliferation
0.50	GO:0043066	negative regulation of apoptotic process
0.47	GO:0007017	microtubule-based process
0.44	GO:0008104	protein localization
0.35	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.34	GO:0099518	vesicle cytoskeletal trafficking
0.34	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.34	GO:0060271	cilium assembly
0.33	GO:0006928	movement of cell or subcellular component

0.85

GO:0019894

kinesin binding

0.81	GO:0005871	kinesin complex
0.55	GO:1990075	periciliary membrane compartment
0.53	GO:0032391	photoreceptor connecting cilium
0.52	GO:0030990	intraciliary transport particle
0.51	GO:0005876	spindle microtubule
0.51	GO:0036064	ciliary basal body
0.51	GO:0005930	axoneme
0.50	GO:0000794	condensed nuclear chromosome
0.50	GO:0005813	centrosome
0.47	GO:0005794	Golgi apparatus

tr|T1G0E4|T1G0E4_HELRO
Uncharacterized protein
Search

PTPMT1

0.92	Phosphatidylglycerophosphatase and protein-tyrosine phosphatase

0.75	GO:0035335	peptidyl-tyrosine dephosphorylation
0.45	GO:0033566	gamma-tubulin complex localization
0.38	GO:0016567	protein ubiquitination
0.37	GO:0006655	phosphatidylglycerol biosynthetic process
0.36	GO:0032048	cardiolipin metabolic process
0.35	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus
0.34	GO:0009190	cyclic nucleotide biosynthetic process
0.33	GO:0046488	phosphatidylinositol metabolic process
0.33	GO:0006486	protein glycosylation
0.33	GO:0035556	intracellular signal transduction

0.79	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.75	GO:0004725	protein tyrosine phosphatase activity
0.48	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
0.38	GO:0004842	ubiquitin-protein transferase activity
0.38	GO:0008962	phosphatidylglycerophosphatase activity
0.34	GO:0004576	oligosaccharyl transferase activity
0.34	GO:0016849	phosphorus-oxygen lyase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.33	GO:0019001	guanyl nucleotide binding

0.45	GO:0008274	gamma-tubulin ring complex
0.39	GO:0005680	anaphase-promoting complex
0.38	GO:0005739	mitochondrion
0.35	GO:0031967	organelle envelope
0.35	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

0.79	EC:3.1.3	GO:0008138
0.48	KEGG:R04404	GO:0004439

tr|T1G0E5|T1G0E5_HELRO
Uncharacterized protein
Search

0.78	Prenyl protein peptidase

0.48	GO:0006508	proteolysis
0.39	GO:0080120	CAAX-box protein maturation
0.34	GO:0032328	alanine transport
0.33	GO:0006814	sodium ion transport

0.49	GO:0008233	peptidase activity
0.34	GO:0015655	alanine:sodium symporter activity

0.38	GO:0030176	integral component of endoplasmic reticulum membrane
0.35	GO:0070461	SAGA-type complex

0.49

GO:0008233

tr|T1G0E6|T1G0E6_HELRO
Uncharacterized protein
Search

0.63	GO:0006468	protein phosphorylation
0.34	GO:0015074	DNA integration

0.64	GO:0004672	protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003676	nucleic acid binding

0.30

GO:0031224

intrinsic component of membrane

tr|T1G0E7|T1G0E7_HELRO
Uncharacterized protein
Search

0.38	Metal-dependent phosphohydrolase

0.39	GO:0046177	D-gluconate catabolic process
0.36	GO:0007186	G-protein coupled receptor signaling pathway
0.36	GO:0016310	phosphorylation
0.35	GO:0036211	protein modification process
0.34	GO:0044267	cellular protein metabolic process
0.34	GO:0055114	oxidation-reduction process

0.45	GO:0016787	hydrolase activity
0.38	GO:0046316	gluconokinase activity
0.38	GO:0031683	G-protein beta/gamma-subunit complex binding
0.37	GO:0043168	anion binding
0.37	GO:0072341	modified amino acid binding
0.36	GO:0036094	small molecule binding
0.36	GO:0097367	carbohydrate derivative binding
0.36	GO:0033218	amide binding
0.36	GO:1901265	nucleoside phosphate binding
0.35	GO:0004672	protein kinase activity

0.52	GO:0009507	chloroplast
0.42	GO:0005829	cytosol
0.35	GO:0005634	nucleus

0.45	EC:3	GO:0016787
0.38	KEGG:R01737	GO:0046316

tr|T1G0E8|T1G0E8_HELRO
Uncharacterized protein
Search

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.49	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.48	GO:0051967	negative regulation of synaptic transmission, glutamatergic
0.48	GO:0048148	behavioral response to cocaine
0.48	GO:0014059	regulation of dopamine secretion
0.47	GO:1900166	regulation of glial cell-derived neurotrophic factor secretion
0.47	GO:0048149	behavioral response to ethanol
0.47	GO:0051944	positive regulation of catecholamine uptake involved in synaptic transmission
0.47	GO:0034776	response to histamine
0.47	GO:0035815	positive regulation of renal sodium excretion

0.77	GO:0004989	octopamine receptor activity
0.64	GO:0004952	dopamine neurotransmitter receptor activity
0.48	GO:0035240	dopamine binding
0.42	GO:0004935	adrenergic receptor activity
0.42	GO:0042802	identical protein binding
0.36	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.35	GO:0035255	ionotropic glutamate receptor binding
0.34	GO:0046982	protein heterodimerization activity
0.34	GO:0051378	serotonin binding
0.34	GO:0016907	G-protein coupled acetylcholine receptor activity

0.54	GO:0005887	integral component of plasma membrane
0.45	GO:0060170	ciliary membrane
0.44	GO:0097730	non-motile cilium
0.44	GO:0097458	neuron part
0.40	GO:0099501	exocytic vesicle membrane
0.38	GO:0044456	synapse part
0.35	GO:0016328	lateral plasma membrane
0.35	GO:0036126	sperm flagellum
0.35	GO:0001669	acrosomal vesicle
0.35	GO:0032279	asymmetric synapse

0.36

GO:0004715

tr|T1G0E9|T1G0E9_HELRO
Uncharacterized protein
Search

MNME

0.45	tRNA modification GTPase TrmE

0.67	GO:0006400	tRNA modification
0.35	GO:0090646	mitochondrial tRNA processing
0.35	GO:1900864	mitochondrial RNA modification
0.34	GO:0070525	tRNA threonylcarbamoyladenosine metabolic process
0.31	GO:0042254	ribosome biogenesis

0.67	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0046872	metal ion binding

0.46	GO:0005737	cytoplasm
0.33	GO:0019866	organelle inner membrane
0.33	GO:0043231	intracellular membrane-bounded organelle

tr|T1G0F0|T1G0F0_HELRO
Uncharacterized protein
Search

0.62	GO:0070247	regulation of natural killer cell apoptotic process
0.60	GO:1990001	inhibition of cysteine-type endopeptidase activity involved in apoptotic process
0.57	GO:0090307	mitotic spindle assembly
0.56	GO:0016567	protein ubiquitination
0.53	GO:0006915	apoptotic process
0.52	GO:0042127	regulation of cell proliferation
0.49	GO:0009966	regulation of signal transduction

0.58	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.57	GO:0004842	ubiquitin-protein transferase activity
0.51	GO:0016874	ligase activity
0.40	GO:0046872	metal ion binding

0.52	GO:0005815	microtubule organizing center
0.50	GO:0005794	Golgi apparatus
0.48	GO:0005829	cytosol
0.47	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.51	EC:6	GO:0016874
0.57	KEGG:R03876	GO:0004842

tr|T1G0F1|T1G0F1_HELRO
Phospholipid-transporting ATPase
Search

ATP8B2

0.59	Phospholipid-transporting ATPase

0.80	GO:0045332	phospholipid translocation
0.45	GO:0007030	Golgi organization
0.35	GO:0043312	neutrophil degranulation

0.81	GO:0004012	phospholipid-translocating ATPase activity
0.64	GO:0000287	magnesium ion binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.45	GO:0005794	Golgi apparatus
0.40	GO:0005886	plasma membrane
0.35	GO:0035579	specific granule membrane
0.35	GO:0070821	tertiary granule membrane
0.30	GO:0016021	integral component of membrane

0.81

EC:3.6.3.1

GO:0004012

tr|T1G0F2|T1G0F2_HELRO
Protein CLP1 homolog
Search

CLP1

0.86	Polyribonucleotide 5'-hydroxyl-kinase Clp1

0.79	GO:0031124	mRNA 3'-end processing
0.54	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation
0.53	GO:0035087	siRNA loading onto RISC involved in RNA interference
0.44	GO:0021522	spinal cord motor neuron differentiation
0.44	GO:0016310	phosphorylation
0.42	GO:0007420	brain development
0.41	GO:0006379	mRNA cleavage
0.41	GO:0043631	RNA polyadenylation
0.37	GO:0030423	targeting of mRNA for destruction involved in RNA interference
0.33	GO:0032958	inositol phosphate biosynthetic process

0.55	GO:0051736	ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0051733	polydeoxyribonucleotide kinase activity
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0019001	guanyl nucleotide binding
0.32	GO:0016491	oxidoreductase activity
0.32	GO:0019829	cation-transporting ATPase activity
0.31	GO:0003723	RNA binding

0.78	GO:0005849	mRNA cleavage factor complex
0.55	GO:0000214	tRNA-intron endonuclease complex
0.33	GO:0033167	ARC complex
0.32	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016491

tr|T1G0F3|T1G0F3_HELRO
Uncharacterized protein
Search

0.46	G-protein coupled receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.55	GO:0097746	regulation of blood vessel diameter
0.51	GO:0006940	regulation of smooth muscle contraction
0.50	GO:0030168	platelet activation
0.49	GO:1903522	regulation of blood circulation
0.47	GO:0007210	serotonin receptor signaling pathway
0.47	GO:0006939	smooth muscle contraction
0.46	GO:0007267	cell-cell signaling
0.46	GO:0050795	regulation of behavior
0.44	GO:0040012	regulation of locomotion

0.73	GO:0008227	G-protein coupled amine receptor activity
0.66	GO:0099528	G-protein coupled neurotransmitter receptor activity
0.47	GO:0099589	serotonin receptor activity
0.44	GO:0031694	alpha-2A adrenergic receptor binding
0.44	GO:0051379	epinephrine binding
0.40	GO:0042803	protein homodimerization activity
0.40	GO:0046982	protein heterodimerization activity
0.37	GO:0051378	serotonin binding
0.37	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.36	GO:0015464	acetylcholine receptor activity

0.46	GO:0005887	integral component of plasma membrane
0.38	GO:0043679	axon terminus
0.37	GO:0030424	axon
0.34	GO:0005737	cytoplasm
0.33	GO:0097708	intracellular vesicle
0.33	GO:0012505	endomembrane system

0.37

GO:0004715

tr|T1G0F4|T1G0F4_HELRO
Uncharacterized protein
Search

tr|T1G0F5|T1G0F5_HELRO
Uncharacterized protein
Search

0.58	Glycogenin glucosyltransferase

0.38

GO:0005978

glycogen biosynthetic process

0.65

GO:0016757

transferase activity, transferring glycosyl groups

0.37	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.65

GO:0016757

tr|T1G0F6|T1G0F6_HELRO
Uncharacterized protein
Search

tr|T1G0F8|T1G0F8_HELRO
Palmitoyltransferase
Search

0.34	Palmitoyltransferase

0.42	GO:0018345	protein palmitoylation
0.34	GO:1903146	regulation of autophagy of mitochondrion
0.34	GO:1903955	positive regulation of protein targeting to mitochondrion
0.33	GO:0010951	negative regulation of endopeptidase activity
0.33	GO:0055114	oxidation-reduction process

0.79	GO:0019706	protein-cysteine S-palmitoyltransferase activity
0.33	GO:0004867	serine-type endopeptidase inhibitor activity
0.33	GO:0016491	oxidoreductase activity

0.34	GO:0012505	endomembrane system
0.33	GO:0005737	cytoplasm
0.33	GO:0043231	intracellular membrane-bounded organelle
0.32	GO:0031984	organelle subcompartment
0.30	GO:0016020	membrane

0.79

GO:0019706

tr|T1G0F9|T1G0F9_HELRO
Uncharacterized protein
Search

tr|T1G0G0|T1G0G0_HELRO
Phosphoinositide phospholipase C
Search

0.24	Phosphoinositide phospholipase C

0.73	GO:0007264	small GTPase mediated signal transduction
0.72	GO:0016042	lipid catabolic process
0.63	GO:0065009	regulation of molecular function
0.53	GO:0032835	glomerulus development
0.49	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.49	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.47	GO:0043410	positive regulation of MAPK cascade
0.46	GO:0046578	regulation of Ras protein signal transduction
0.42	GO:0030198	extracellular matrix organization
0.35	GO:1902633	1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolic process

0.82	GO:0004435	phosphatidylinositol phospholipase C activity
0.72	GO:0005085	guanyl-nucleotide exchange factor activity
0.61	GO:0004871	signal transducer activity
0.34	GO:0017016	Ras GTPase binding

0.45	GO:0005622	intracellular
0.39	GO:0005886	plasma membrane
0.33	GO:0043228	non-membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.82	EC:3.1.4.11	GO:0004435
0.82	KEGG:R03435	GO:0004435

tr|T1G0G1|T1G0G1_HELRO
Coronin
Search

0.65

Coronin

0.62

GO:0030036

actin cytoskeleton organization

0.78

GO:0051015

actin filament binding

0.65	GO:0017053	transcriptional repressor complex
0.46	GO:0015629	actin cytoskeleton
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|T1G0G2|T1G0G2_HELRO
Uncharacterized protein
Search

CA2

0.43	Cytoplasmic carbonic anhydrase II

0.70	GO:0006730	one-carbon metabolic process
0.50	GO:0044070	regulation of anion transport
0.49	GO:0015670	carbon dioxide transport
0.48	GO:0038166	angiotensin-activated signaling pathway
0.48	GO:0006885	regulation of pH
0.47	GO:2000878	positive regulation of oligopeptide transport
0.47	GO:2001148	regulation of dipeptide transmembrane transport
0.47	GO:0032230	positive regulation of synaptic transmission, GABAergic
0.46	GO:2000021	regulation of ion homeostasis
0.46	GO:0030004	cellular monovalent inorganic cation homeostasis

0.76	GO:0004089	carbonate dehydratase activity
0.61	GO:0008270	zinc ion binding
0.49	GO:0004064	arylesterase activity
0.35	GO:0016151	nickel cation binding
0.33	GO:0005515	protein binding
0.32	GO:0016301	kinase activity

0.47	GO:0045177	apical part of cell
0.42	GO:0043209	myelin sheath
0.42	GO:0005829	cytosol
0.39	GO:0005886	plasma membrane
0.38	GO:0005739	mitochondrion
0.36	GO:0005902	microvillus
0.36	GO:0030424	axon
0.35	GO:0005615	extracellular space
0.34	GO:1903561	extracellular vesicle
0.33	GO:0043233	organelle lumen

0.76

GO:0004089

tr|T1G0G3|T1G0G3_HELRO
Uncharacterized protein
Search

0.10	Carboxylic ester hydrolase (Fragment)

0.40	GO:0006629	lipid metabolic process
0.33	GO:1901565	organonitrogen compound catabolic process
0.33	GO:0044248	cellular catabolic process
0.33	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.33	GO:0043547	positive regulation of GTPase activity
0.33	GO:0043603	cellular amide metabolic process
0.32	GO:0006468	protein phosphorylation
0.32	GO:0055085	transmembrane transport

0.49	GO:0016787	hydrolase activity
0.36	GO:0016757	transferase activity, transferring glycosyl groups
0.36	GO:0005549	odorant binding
0.33	GO:0004984	olfactory receptor activity
0.33	GO:0005096	GTPase activator activity
0.32	GO:0030246	carbohydrate binding
0.32	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0016020

membrane

0.49

GO:0016787

tr|T1G0G4|T1G0G4_HELRO
Uncharacterized protein
Search

0.67	Homeodomain transcription factor (Fragment)

0.33	GO:0006357	regulation of transcription by RNA polymerase II
0.32	GO:0097659	nucleic acid-templated transcription
0.32	GO:0010467	gene expression
0.32	GO:0034645	cellular macromolecule biosynthetic process

0.47	GO:0003677	DNA binding
0.33	GO:0046983	protein dimerization activity
0.33	GO:0003700	DNA binding transcription factor activity

0.33	GO:0005783	endoplasmic reticulum
0.33	GO:0005634	nucleus
0.30	GO:0044425	membrane part

tr|T1G0G5|T1G0G5_HELRO
Uncharacterized protein
Search

GABARAP

0.94	GABA(A) receptor-associated protein b

0.77	GO:0006914	autophagy
0.50	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors
0.47	GO:0006995	cellular response to nitrogen starvation
0.47	GO:0061726	mitochondrion disassembly
0.46	GO:0000226	microtubule cytoskeleton organization
0.45	GO:0007033	vacuole organization
0.43	GO:0070925	organelle assembly
0.40	GO:0060322	head development
0.39	GO:0007417	central nervous system development
0.39	GO:0048513	animal organ development

0.51	GO:0050811	GABA receptor binding
0.50	GO:0031625	ubiquitin protein ligase binding
0.49	GO:0048487	beta-tubulin binding
0.45	GO:0008017	microtubule binding
0.43	GO:0030957	Tat protein binding
0.34	GO:0016791	phosphatase activity
0.33	GO:0004252	serine-type endopeptidase activity
0.32	GO:0046872	metal ion binding

0.55	GO:0000421	autophagosome membrane
0.50	GO:0005790	smooth endoplasmic reticulum
0.50	GO:0097225	sperm midpiece
0.48	GO:0005930	axoneme
0.47	GO:0005764	lysosome
0.46	GO:0005875	microtubule associated complex
0.45	GO:0015629	actin cytoskeleton
0.45	GO:0005794	Golgi apparatus
0.42	GO:0005829	cytosol
0.39	GO:0005886	plasma membrane

0.34

EC:3.1.3 EC:3.1.3.41

GO:0016791

tr|T1G0G6|T1G0G6_HELRO
Uncharacterized protein
Search

0.36	GO:0008380	RNA splicing
0.35	GO:0006397	mRNA processing
0.34	GO:0006366	transcription by RNA polymerase II

0.58	GO:0003723	RNA binding
0.37	GO:0043175	RNA polymerase core enzyme binding
0.34	GO:0019904	protein domain specific binding

0.48	GO:0005654	nucleoplasm
0.37	GO:0016363	nuclear matrix
0.36	GO:0005681	spliceosomal complex

tr|T1G0G7|T1G0G7_HELRO
Synaptosomal-associated protein
Search

0.77	Synaptosomal-associated protein 25

0.78	GO:1990926	short-term synaptic potentiation
0.78	GO:0099590	neurotransmitter receptor internalization
0.77	GO:0007269	neurotransmitter secretion
0.77	GO:0098881	exocytic insertion of neurotransmitter receptor to plasma membrane
0.76	GO:1903540	establishment of protein localization to postsynaptic membrane
0.76	GO:0031915	positive regulation of synaptic plasticity
0.76	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels
0.73	GO:0097120	receptor localization to synapse
0.73	GO:0060291	long-term synaptic potentiation
0.72	GO:0008306	associative learning

0.77	GO:0000149	SNARE binding
0.65	GO:0005484	SNAP receptor activity
0.43	GO:0048306	calcium-dependent protein binding
0.37	GO:0047485	protein N-terminus binding
0.37	GO:0044325	ion channel binding
0.37	GO:0017022	myosin binding
0.36	GO:0005249	voltage-gated potassium channel activity
0.36	GO:0019904	protein domain specific binding

0.81	GO:0070032	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex
0.75	GO:0031083	BLOC-1 complex
0.74	GO:0098793	presynapse
0.72	GO:0043005	neuron projection
0.69	GO:0043209	myelin sheath
0.68	GO:0070382	exocytic vesicle
0.67	GO:0048471	perinuclear region of cytoplasm
0.67	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.67	GO:0005802	trans-Golgi network
0.67	GO:0036477	somatodendritic compartment

tr|T1G0G8|T1G0G8_HELRO
Uncharacterized protein
Search

0.55	Tyrosine-protein phosphatase (Fragment)

0.75	GO:0035335	peptidyl-tyrosine dephosphorylation
0.51	GO:0051463	negative regulation of cortisol secretion
0.51	GO:0033277	abortive mitotic cell cycle
0.51	GO:0060125	negative regulation of growth hormone secretion
0.50	GO:0061582	intestinal epithelial cell migration
0.50	GO:0036302	atrioventricular canal development
0.49	GO:0033629	negative regulation of cell adhesion mediated by integrin
0.49	GO:2001275	positive regulation of glucose import in response to insulin stimulus
0.49	GO:0060020	Bergmann glial cell differentiation
0.49	GO:0035855	megakaryocyte development

0.75	GO:0004725	protein tyrosine phosphatase activity
0.49	GO:0051428	peptide hormone receptor binding
0.49	GO:0005158	insulin receptor binding
0.48	GO:0005070	SH3/SH2 adaptor activity
0.47	GO:0030971	receptor tyrosine kinase binding
0.46	GO:0050839	cell adhesion molecule binding
0.37	GO:0031748	D1 dopamine receptor binding
0.36	GO:0043274	phospholipase binding
0.36	GO:0043560	insulin receptor substrate binding
0.36	GO:0033549	MAP kinase phosphatase activity

0.41	GO:0005737	cytoplasm
0.41	GO:0005634	nucleus
0.40	GO:0043234	protein complex
0.35	GO:0097708	intracellular vesicle
0.34	GO:0042105	alpha-beta T cell receptor complex
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.33	GO:0005911	cell-cell junction
0.33	GO:0044446	intracellular organelle part
0.32	GO:0030529	intracellular ribonucleoprotein complex

0.75	EC:3.1.3.48	GO:0004725
0.35	KEGG:R04545	GO:0046934

tr|T1G0G9|T1G0G9_HELRO
Uncharacterized protein
Search

0.54	Zinc finger protein 997

0.38	GO:0060255	regulation of macromolecule metabolic process
0.38	GO:0080090	regulation of primary metabolic process
0.38	GO:0031323	regulation of cellular metabolic process
0.38	GO:0051171	regulation of nitrogen compound metabolic process
0.38	GO:0009889	regulation of biosynthetic process
0.34	GO:1905269	positive regulation of chromatin organization
0.33	GO:0006351	transcription, DNA-templated
0.33	GO:0009893	positive regulation of metabolic process
0.33	GO:0040034	regulation of development, heterochronic
0.32	GO:0032259	methylation

0.51	GO:0003676	nucleic acid binding
0.38	GO:0046872	metal ion binding
0.37	GO:0003700	DNA binding transcription factor activity
0.32	GO:0008168	methyltransferase activity

0.40	GO:0005634	nucleus
0.33	GO:0019013	viral nucleocapsid
0.32	GO:0030529	intracellular ribonucleoprotein complex

0.32

GO:0008168

tr|T1G0H0|T1G0H0_HELRO
Uncharacterized protein
Search

tr|T1G0H1|T1G0H1_HELRO
Uncharacterized protein
Search

UBR5

0.91	Ubiquitin protein ligase E3 component n-recognin 5

0.72	GO:0016567	protein ubiquitination
0.56	GO:1901314	regulation of histone H2A K63-linked ubiquitination
0.56	GO:0033183	negative regulation of histone ubiquitination
0.56	GO:1900045	negative regulation of protein K63-linked ubiquitination
0.55	GO:0050847	progesterone receptor signaling pathway
0.55	GO:0035413	positive regulation of catenin import into nucleus
0.55	GO:0033160	positive regulation of protein import into nucleus, translocation
0.54	GO:2000780	negative regulation of double-strand break repair
0.52	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.47	GO:0010628	positive regulation of gene expression

0.78	GO:0043130	ubiquitin binding
0.73	GO:0004842	ubiquitin-protein transferase activity
0.63	GO:0008270	zinc ion binding
0.59	GO:0003723	RNA binding
0.55	GO:0016874	ligase activity
0.51	GO:0061659	ubiquitin-like protein ligase activity
0.34	GO:0019904	protein domain specific binding

0.50	GO:0048471	perinuclear region of cytoplasm
0.46	GO:0005654	nucleoplasm
0.46	GO:0005829	cytosol
0.42	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

0.55	EC:6	GO:0016874
0.73	KEGG:R03876	GO:0004842

tr|T1G0H2|T1G0H2_HELRO
Uncharacterized protein
Search

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.45	GO:0007399	nervous system development
0.44	GO:0016318	ommatidial rotation
0.42	GO:0060560	developmental growth involved in morphogenesis
0.42	GO:0048588	developmental cell growth
0.42	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.41	GO:0000904	cell morphogenesis involved in differentiation
0.41	GO:0007267	cell-cell signaling
0.41	GO:0120036	plasma membrane bounded cell projection organization
0.40	GO:0006928	movement of cell or subcellular component

0.70	GO:0005509	calcium ion binding
0.35	GO:0004872	receptor activity
0.34	GO:0017022	myosin binding
0.34	GO:0008013	beta-catenin binding
0.34	GO:0050839	cell adhesion molecule binding
0.34	GO:0004871	signal transducer activity
0.33	GO:0042803	protein homodimerization activity
0.33	GO:0003777	microtubule motor activity
0.33	GO:0003723	RNA binding

0.56	GO:0005886	plasma membrane
0.35	GO:0005913	cell-cell adherens junction
0.34	GO:0030175	filopodium
0.34	GO:0055037	recycling endosome
0.34	GO:0043296	apical junction complex
0.34	GO:0005576	extracellular region
0.34	GO:0030286	dynein complex
0.34	GO:0005938	cell cortex
0.33	GO:0019898	extrinsic component of membrane
0.33	GO:0098796	membrane protein complex

tr|T1G0H3|T1G0H3_HELRO
Uncharacterized protein
Search

0.85	Four and a half LIM domains protein 2

0.38

GO:0050832

defense response to fungus

0.59	GO:0008270	zinc ion binding
0.32	GO:0003676	nucleic acid binding
0.32	GO:0016740	transferase activity

0.30

GO:0044425

membrane part

0.32

GO:0016740

tr|T1G0H4|T1G0H4_HELRO
Transporter
Search

0.44	Transporter

0.76	GO:0006836	neurotransmitter transport
0.55	GO:0055085	transmembrane transport
0.46	GO:0015872	dopamine transport
0.40	GO:0090493	catecholamine uptake
0.40	GO:0007268	chemical synaptic transmission
0.39	GO:0006820	anion transport
0.38	GO:0015849	organic acid transport
0.38	GO:1905847	negative regulation of cellular response to oxidopamine
0.38	GO:0060092	regulation of synaptic transmission, glycinergic
0.38	GO:1905803	negative regulation of cellular response to manganese ion

0.79	GO:0005328	neurotransmitter:sodium symporter activity
0.46	GO:0005329	dopamine transmembrane transporter activity
0.40	GO:0005283	sodium:amino acid symporter activity
0.38	GO:0015187	glycine transmembrane transporter activity
0.36	GO:0005254	chloride channel activity
0.35	GO:0005275	amine transmembrane transporter activity
0.34	GO:0015185	gamma-aminobutyric acid transmembrane transporter activity
0.34	GO:0035240	dopamine binding
0.34	GO:0015355	secondary active monocarboxylate transmembrane transporter activity
0.34	GO:0047485	protein N-terminus binding

0.44	GO:0005887	integral component of plasma membrane
0.40	GO:0044456	synapse part
0.39	GO:0097458	neuron part
0.39	GO:0120025	plasma membrane bounded cell projection
0.38	GO:0044297	cell body
0.36	GO:0031256	leading edge membrane
0.36	GO:0098590	plasma membrane region
0.35	GO:0044463	cell projection part
0.33	GO:0045121	membrane raft
0.33	GO:0009986	cell surface

tr|T1G0H5|T1G0H5_HELRO
Sodium channel protein
Search

0.45	Voltage-gated sodium channel

0.77	GO:0035725	sodium ion transmembrane transport
0.76	GO:0034765	regulation of ion transmembrane transport
0.54	GO:0019233	sensory perception of pain
0.41	GO:0019228	neuronal action potential
0.38	GO:0036269	swimming behavior
0.38	GO:0002082	regulation of oxidative phosphorylation
0.38	GO:0006110	regulation of glycolytic process
0.38	GO:0086010	membrane depolarization during action potential
0.37	GO:0099536	synaptic signaling
0.34	GO:0071805	potassium ion transmembrane transport

0.84	GO:0005248	voltage-gated sodium channel activity
0.74	GO:0022832	voltage-gated channel activity
0.71	GO:0022839	ion gated channel activity
0.71	GO:0008381	mechanosensitive ion channel activity
0.59	GO:0005509	calcium ion binding
0.36	GO:0008081	phosphoric diester hydrolase activity
0.34	GO:0005267	potassium channel activity

0.83	GO:0001518	voltage-gated sodium channel complex
0.34	GO:0008076	voltage-gated potassium channel complex

0.36

EC:3.1.4

GO:0008081

tr|T1G0H6|T1G0H6_HELRO
Uncharacterized protein
Search

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.45	GO:0032501	multicellular organismal process
0.44	GO:0001667	ameboidal-type cell migration
0.42	GO:0048856	anatomical structure development
0.41	GO:0007267	cell-cell signaling
0.38	GO:0007626	locomotory behavior
0.37	GO:0060989	lipid tube assembly involved in organelle fusion
0.37	GO:0030154	cell differentiation
0.37	GO:0120036	plasma membrane bounded cell projection organization
0.36	GO:0008333	endosome to lysosome transport

0.70	GO:0005509	calcium ion binding
0.36	GO:0004888	transmembrane signaling receptor activity
0.36	GO:0045296	cadherin binding
0.35	GO:0045295	gamma-catenin binding
0.35	GO:0032794	GTPase activating protein binding
0.35	GO:0030506	ankyrin binding
0.35	GO:0008013	beta-catenin binding
0.34	GO:0042802	identical protein binding
0.34	GO:0140096	catalytic activity, acting on a protein
0.34	GO:0004022	alcohol dehydrogenase (NAD) activity

0.56	GO:0005886	plasma membrane
0.45	GO:0005913	cell-cell adherens junction
0.38	GO:0032420	stereocilium
0.36	GO:0005615	extracellular space
0.35	GO:1903561	extracellular vesicle
0.35	GO:0030027	lamellipodium
0.35	GO:0030864	cortical actin cytoskeleton
0.35	GO:0043296	apical junction complex
0.35	GO:0098857	membrane microdomain
0.34	GO:0005802	trans-Golgi network

0.34

EC:1.1.1.1

GO:0004022

tr|T1G0H7|T1G0H7_HELRO
Uncharacterized protein
Search

PGAM5

0.88	PGAM family member 5, mitochondrial serine/threonine protein phosphatase

0.74	GO:0070266	necroptotic process
0.64	GO:0043547	positive regulation of GTPase activity
0.62	GO:0006470	protein dephosphorylation
0.52	GO:0007165	signal transduction
0.46	GO:0090141	positive regulation of mitochondrial fission
0.37	GO:0016236	macroautophagy

0.77	GO:0009400	signal transducer, downstream of receptor, with serine/threonine phosphatase activity
0.64	GO:0005096	GTPase activator activity
0.62	GO:0032403	protein complex binding
0.36	GO:0004619	phosphoglycerate mutase activity

0.53	GO:0005739	mitochondrion
0.44	GO:0031968	organelle outer membrane
0.30	GO:0016021	integral component of membrane

0.36

EC:5.4.2.1

GO:0004619

tr|T1G0H8|T1G0H8_HELRO
Uncharacterized protein
Search

0.63	GO:0006468	protein phosphorylation
0.40	GO:0007229	integrin-mediated signaling pathway
0.37	GO:0035556	intracellular signal transduction
0.36	GO:0000122	negative regulation of transcription by RNA polymerase II
0.36	GO:0006808	regulation of nitrogen utilization
0.36	GO:0018212	peptidyl-tyrosine modification
0.36	GO:0006952	defense response
0.36	GO:0009607	response to biotic stimulus

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0001871	pattern binding
0.40	GO:0030246	carbohydrate binding
0.38	GO:0004871	signal transducer activity
0.37	GO:0005516	calmodulin binding
0.36	GO:0008889	glycerophosphodiester phosphodiesterase activity
0.35	GO:0099600	transmembrane receptor activity

0.40	GO:0005829	cytosol
0.38	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.36

EC:3.1.4.46

GO:0008889

tr|T1G0H9|T1G0H9_HELRO
Uncharacterized protein
Search

0.63

GO:0097502

mannosylation

0.69

GO:0004377

GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity

0.58	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.69

EC:2.4.1.131

GO:0004377

tr|T1G0I0|T1G0I0_HELRO
Uncharacterized protein
Search

0.53	Sulfotransferase

0.34	GO:0055003	cardiac myofibril assembly
0.34	GO:0006477	protein sulfation
0.33	GO:0045214	sarcomere organization
0.33	GO:0060047	heart contraction

0.76

GO:0008146

sulfotransferase activity

0.33

GO:0005887

integral component of plasma membrane

0.76

EC:2.8.2

GO:0008146

tr|T1G0I1|T1G0I1_HELRO
Uncharacterized protein
Search

PGS1

0.42	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

0.79	GO:0032049	cardiolipin biosynthetic process
0.39	GO:0046339	diacylglycerol metabolic process
0.36	GO:0051881	regulation of mitochondrial membrane potential
0.35	GO:0042127	regulation of cell proliferation
0.34	GO:0007018	microtubule-based movement
0.34	GO:0006030	chitin metabolic process
0.33	GO:0031145	anaphase-promoting complex-dependent catabolic process
0.33	GO:0018108	peptidyl-tyrosine phosphorylation
0.33	GO:0033499	galactose catabolic process via UDP-galactose
0.33	GO:0043043	peptide biosynthetic process

0.78	GO:0008444	CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005509	calcium ion binding
0.34	GO:0003777	microtubule motor activity
0.33	GO:0003735	structural constituent of ribosome
0.33	GO:0016887	ATPase activity
0.33	GO:0004713	protein tyrosine kinase activity
0.33	GO:0008108	UDP-glucose:hexose-1-phosphate uridylyltransferase activity

0.50	GO:0005783	endoplasmic reticulum
0.47	GO:0005739	mitochondrion
0.36	GO:0031967	organelle envelope
0.36	GO:0031090	organelle membrane
0.33	GO:0005680	anaphase-promoting complex
0.33	GO:0005840	ribosome
0.32	GO:0005576	extracellular region
0.32	GO:0070469	respiratory chain
0.30	GO:0016021	integral component of membrane

0.78	EC:2.7.8.5	GO:0008444
0.78	KEGG:R01801	GO:0008444

tr|T1G0I2|T1G0I2_HELRO
Uncharacterized protein
Search

0.73	regulator of microtubule dynamics protein 1-like

0.45

GO:0006874

cellular calcium ion homeostasis

0.35	GO:0005544	calcium-dependent phospholipid binding
0.34	GO:0005509	calcium ion binding

0.45	GO:0005741	mitochondrial outer membrane
0.36	GO:0000922	spindle pole
0.34	GO:0005634	nucleus
0.30	GO:0044425	membrane part

tr|T1G0I3|T1G0I3_HELRO
Uncharacterized protein
Search

0.44	Putative syntaxin-binding protein 2 (Fragment)

0.30

GO:0044425

membrane part

tr|T1G0I4|T1G0I4_HELRO
Uncharacterized protein
Search

0.21	Sodium-dependent proline transporter

0.76	GO:0006836	neurotransmitter transport
0.55	GO:0055085	transmembrane transport
0.46	GO:0015824	proline transport
0.44	GO:0015844	monoamine transport
0.42	GO:0015850	organic hydroxy compound transport
0.41	GO:0015696	ammonium transport
0.39	GO:0001505	regulation of neurotransmitter levels
0.39	GO:0042221	response to chemical
0.39	GO:0098657	import into cell
0.39	GO:0051649	establishment of localization in cell

0.79	GO:0005328	neurotransmitter:sodium symporter activity
0.46	GO:0015193	L-proline transmembrane transporter activity
0.45	GO:0008504	monoamine transmembrane transporter activity
0.42	GO:1901618	organic hydroxy compound transmembrane transporter activity
0.42	GO:0008519	ammonium transmembrane transporter activity
0.38	GO:0005261	cation channel activity
0.37	GO:0005343	organic acid:sodium symporter activity
0.36	GO:0005308	creatine transmembrane transporter activity
0.36	GO:0015296	anion:cation symporter activity
0.35	GO:0005416	amino acid:cation symporter activity

0.43	GO:0005887	integral component of plasma membrane
0.41	GO:0098793	presynapse
0.41	GO:0043005	neuron projection
0.39	GO:0120038	plasma membrane bounded cell projection part
0.34	GO:0098857	membrane microdomain
0.34	GO:0098590	plasma membrane region
0.34	GO:0097386	glial cell projection
0.33	GO:0005903	brush border
0.33	GO:0043025	neuronal cell body
0.33	GO:0009986	cell surface

tr|T1G0I5|T1G0I5_HELRO
Uncharacterized protein
Search

0.39	Mitochondrial atp synthase chain,atp synthase chain mitochondrial

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.39	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.35	GO:0050909	sensory perception of taste
0.34	GO:0021762	substantia nigra development
0.34	GO:0042407	cristae formation
0.33	GO:0007165	signal transduction
0.33	GO:0006839	mitochondrial transport
0.33	GO:0046907	intracellular transport
0.32	GO:0006518	peptide metabolic process

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.40	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
0.39	GO:0019829	cation-transporting ATPase activity
0.33	GO:0004871	signal transducer activity
0.32	GO:0003735	structural constituent of ribosome
0.32	GO:0005515	protein binding

0.78	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
0.40	GO:0043209	myelin sheath
0.39	GO:0005654	nucleoplasm
0.34	GO:0005759	mitochondrial matrix
0.33	GO:0000313	organellar ribosome
0.33	GO:0070062	extracellular exosome
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1G0I6|T1G0I6_HELRO
Uncharacterized protein
Search

0.11	Zinc finger MYM-type protein (Fragment)

0.34	GO:0006357	regulation of transcription by RNA polymerase II
0.34	GO:0007275	multicellular organism development
0.34	GO:0006313	transposition, DNA-mediated
0.34	GO:0016310	phosphorylation

0.68	GO:0046983	protein dimerization activity
0.35	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.34	GO:0016301	kinase activity
0.34	GO:0004803	transposase activity
0.34	GO:0003677	DNA binding

0.34	GO:0005654	nucleoplasm
0.32	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

tr|T1G0I7|T1G0I7_HELRO
Uncharacterized protein
Search

tr|T1G0I8|T1G0I8_HELRO
Uncharacterized protein
Search

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.50	GO:0060122	inner ear receptor cell stereocilium organization
0.48	GO:0007605	sensory perception of sound
0.48	GO:0007626	locomotory behavior
0.40	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.40	GO:0044331	cell-cell adhesion mediated by cadherin
0.39	GO:0045317	equator specification
0.39	GO:0090176	microtubule cytoskeleton organization involved in establishment of planar polarity
0.38	GO:0001737	establishment of imaginal disc-derived wing hair orientation
0.38	GO:0035159	regulation of tube length, open tracheal system

0.70	GO:0005509	calcium ion binding
0.37	GO:0045296	cadherin binding
0.34	GO:0004872	receptor activity
0.34	GO:0042803	protein homodimerization activity
0.34	GO:0004871	signal transducer activity
0.33	GO:0004022	alcohol dehydrogenase (NAD) activity
0.33	GO:0008417	fucosyltransferase activity
0.32	GO:0030246	carbohydrate binding

0.56	GO:0005886	plasma membrane
0.49	GO:0032420	stereocilium
0.36	GO:0045177	apical part of cell
0.35	GO:0005902	microvillus
0.34	GO:0005911	cell-cell junction
0.33	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0032580	Golgi cisterna membrane
0.33	GO:0005912	adherens junction
0.32	GO:0005739	mitochondrion
0.32	GO:0005634	nucleus

0.33

EC:1.1.1.1

GO:0004022

tr|T1G0I9|T1G0I9_HELRO
Uncharacterized protein
Search

0.73	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.41	GO:0030522	intracellular receptor signaling pathway
0.40	GO:0051254	positive regulation of RNA metabolic process
0.39	GO:0010557	positive regulation of macromolecule biosynthetic process
0.39	GO:0031328	positive regulation of cellular biosynthetic process
0.39	GO:0009888	tissue development

0.70	GO:0003707	steroid hormone receptor activity
0.65	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.39	GO:0003682	chromatin binding
0.39	GO:0044212	transcription regulatory region DNA binding
0.38	GO:0003690	double-stranded DNA binding
0.38	GO:0070016	armadillo repeat domain binding

0.61	GO:0005634	nucleus
0.39	GO:0005667	transcription factor complex
0.36	GO:0044446	intracellular organelle part
0.34	GO:0005783	endoplasmic reticulum
0.30	GO:0031224	intrinsic component of membrane

tr|T1G0J0|T1G0J0_HELRO
Uncharacterized protein
Search

0.90	LON peptidase N-terminal domain and ring finger 1

0.57	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.55	GO:0000209	protein polyubiquitination
0.35	GO:0032958	inositol phosphate biosynthetic process
0.35	GO:0031929	TOR signaling
0.35	GO:0006508	proteolysis
0.33	GO:0065008	regulation of biological quality
0.33	GO:0016310	phosphorylation
0.33	GO:0005975	carbohydrate metabolic process
0.33	GO:0032273	positive regulation of protein polymerization
0.33	GO:0022900	electron transport chain

0.58	GO:0031624	ubiquitin conjugating enzyme binding
0.53	GO:0061630	ubiquitin protein ligase activity
0.52	GO:0046872	metal ion binding
0.35	GO:0008233	peptidase activity
0.34	GO:0016874	ligase activity
0.33	GO:0015035	protein disulfide oxidoreductase activity
0.33	GO:0016301	kinase activity
0.33	GO:0009055	electron transfer activity

0.38	GO:0005622	intracellular
0.33	GO:0043234	protein complex
0.32	GO:0043228	non-membrane-bounded organelle
0.32	GO:0044422	organelle part
0.30	GO:0016020	membrane

0.35

GO:0008233

tr|T1G0J1|T1G0J1_HELRO
Uncharacterized protein
Search

0.64	Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha

0.41	GO:0090249	regulation of cell motility involved in somitogenic axis elongation
0.40	GO:0007525	somatic muscle development
0.39	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.39	GO:0001754	eye photoreceptor cell differentiation
0.39	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.38	GO:0045732	positive regulation of protein catabolic process
0.35	GO:0032509	endosome transport via multivesicular body sorting pathway
0.34	GO:0015031	protein transport
0.33	GO:0006470	protein dephosphorylation

0.70	GO:0005509	calcium ion binding
0.39	GO:0030674	protein binding, bridging
0.33	GO:0004721	phosphoprotein phosphatase activity

0.45	GO:0000159	protein phosphatase type 2A complex
0.35	GO:0000813	ESCRT I complex

0.33

EC:3.1.3.16

GO:0004721

tr|T1G0J2|T1G0J2_HELRO
Uncharacterized protein
Search

0.56	DNA/RNA-binding protein KIN17 isoform B

0.57	GO:0034314	Arp2/3 complex-mediated actin nucleation
0.53	GO:0006011	UDP-glucose metabolic process
0.50	GO:0006260	DNA replication
0.50	GO:0006974	cellular response to DNA damage stimulus
0.42	GO:0000398	mRNA splicing, via spliceosome
0.41	GO:0035874	cellular response to copper ion starvation
0.38	GO:0048638	regulation of developmental growth
0.38	GO:0055085	transmembrane transport

0.57	GO:0070569	uridylyltransferase activity
0.54	GO:0003690	double-stranded DNA binding
0.43	GO:0032555	purine ribonucleotide binding
0.43	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0030554	adenyl nucleotide binding
0.43	GO:0008144	drug binding
0.41	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.36	GO:0003924	GTPase activity
0.36	GO:0032550	purine ribonucleoside binding
0.36	GO:0019001	guanyl nucleotide binding

0.57	GO:0005885	Arp2/3 protein complex
0.49	GO:0005634	nucleus
0.39	GO:0031974	membrane-enclosed lumen
0.38	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016020	membrane

tr|T1G0J3|T1G0J3_HELRO
Uncharacterized protein
Search

0.51	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.51	GO:0036503	ERAD pathway
0.49	GO:0016567	protein ubiquitination
0.33	GO:0006281	DNA repair

0.50	GO:0061630	ubiquitin protein ligase activity
0.45	GO:0046872	metal ion binding
0.39	GO:0016874	ligase activity
0.36	GO:0035091	phosphatidylinositol binding
0.34	GO:0003684	damaged DNA binding
0.33	GO:0003723	RNA binding

0.52	GO:0000836	Hrd1p ubiquitin ligase complex
0.34	GO:0005886	plasma membrane
0.34	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.39

GO:0016874

tr|T1G0J4|T1G0J4_HELRO
60S ribosomal protein L27
Search

RPL27

0.73	60S ribosomal protein L27

0.60	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.42	GO:0016072	rRNA metabolic process
0.41	GO:0042254	ribosome biogenesis
0.35	GO:1904044	response to aldosterone
0.35	GO:0030218	erythrocyte differentiation
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane

0.64	GO:0003735	structural constituent of ribosome
0.35	GO:0032550	purine ribonucleoside binding
0.35	GO:0019001	guanyl nucleotide binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0003723	RNA binding

0.61	GO:0005840	ribosome
0.44	GO:0098556	cytoplasmic side of rough endoplasmic reticulum membrane
0.42	GO:0044445	cytosolic part
0.36	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.34	GO:0005634	nucleus

tr|T1G0J5|T1G0J5_HELRO
Uncharacterized protein
Search

0.10	myosin light chain kinase, smooth muscle-like

0.63	GO:0006468	protein phosphorylation
0.54	GO:0035023	regulation of Rho protein signal transduction
0.48	GO:0065009	regulation of molecular function
0.38	GO:0051598	meiotic recombination checkpoint
0.38	GO:0018193	peptidyl-amino acid modification
0.37	GO:0007155	cell adhesion
0.36	GO:0035556	intracellular signal transduction
0.36	GO:0034769	basement membrane disassembly
0.35	GO:0007099	centriole replication
0.35	GO:1904512	regulation of initiation of premeiotic DNA replication

0.63	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005201	extracellular matrix structural constituent
0.35	GO:0005509	calcium ion binding

0.37	GO:0005604	basement membrane
0.35	GO:0030998	linear element
0.35	GO:0005814	centriole
0.30	GO:0031224	intrinsic component of membrane

tr|T1G0J6|T1G0J6_HELRO
Uncharacterized protein
Search

0.10	Ryanodine receptor 44F (Fragment)

0.84	GO:0051209	release of sequestered calcium ion into cytosol
0.35	GO:0035206	regulation of hemocyte proliferation
0.34	GO:0072347	response to anesthetic
0.34	GO:0060047	heart contraction
0.34	GO:0006936	muscle contraction
0.33	GO:0007275	multicellular organism development

0.85	GO:0005219	ryanodine-sensitive calcium-release channel activity
0.48	GO:0005509	calcium ion binding

0.34	GO:0033017	sarcoplasmic reticulum membrane
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1G0J8|T1G0J8_HELRO
Uncharacterized protein
Search

NCLN

0.69

Nicalin

0.64	GO:0009966	regulation of signal transduction
0.49	GO:0031648	protein destabilization
0.45	GO:2000381	negative regulation of mesoderm development
0.44	GO:0048484	enteric nervous system development
0.43	GO:0043254	regulation of protein complex assembly
0.42	GO:0051241	negative regulation of multicellular organismal process
0.41	GO:2000026	regulation of multicellular organismal development
0.41	GO:0023057	negative regulation of signaling
0.41	GO:0010648	negative regulation of cell communication
0.40	GO:0048585	negative regulation of response to stimulus

0.41	GO:0004177	aminopeptidase activity
0.34	GO:0008890	glycine C-acetyltransferase activity
0.34	GO:0070279	vitamin B6 binding
0.33	GO:0003713	transcription coactivator activity
0.33	GO:0050662	coenzyme binding
0.33	GO:0005515	protein binding
0.33	GO:0016874	ligase activity
0.33	GO:0043168	anion binding
0.32	GO:0003677	DNA binding

0.49	GO:0005789	endoplasmic reticulum membrane
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.41	EC:3.4.11	GO:0004177
0.34	KEGG:R00371	GO:0008890

tr|T1G0J9|T1G0J9_HELRO
Uncharacterized protein
Search

METTL6

0.38	Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial

0.62	GO:0032259	methylation
0.34	GO:0034470	ncRNA processing
0.34	GO:0009451	RNA modification
0.34	GO:0006399	tRNA metabolic process
0.34	GO:0006825	copper ion transport
0.33	GO:0006629	lipid metabolic process
0.33	GO:0016072	rRNA metabolic process
0.32	GO:0042254	ribosome biogenesis
0.32	GO:0044260	cellular macromolecule metabolic process
0.32	GO:0009058	biosynthetic process

0.62	GO:0008168	methyltransferase activity
0.34	GO:0016531	copper chaperone activity
0.34	GO:0140101	catalytic activity, acting on a tRNA
0.33	GO:0008081	phosphoric diester hydrolase activity
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0019001	guanyl nucleotide binding
0.31	GO:0032555	purine ribonucleotide binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.34	GO:0005758	mitochondrial intermembrane space
0.30	GO:0031224	intrinsic component of membrane

0.62

GO:0008168

tr|T1G0K0|T1G0K0_HELRO
Uncharacterized protein
Search

0.62	GO:0006468	protein phosphorylation
0.51	GO:0071689	muscle thin filament assembly
0.49	GO:0045214	sarcomere organization
0.47	GO:0007498	mesoderm development
0.41	GO:0071688	striated muscle myosin thick filament assembly
0.40	GO:0006941	striated muscle contraction
0.39	GO:0035335	peptidyl-tyrosine dephosphorylation
0.33	GO:0006508	proteolysis
0.33	GO:0007154	cell communication

0.63	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0008307	structural constituent of muscle
0.41	GO:0097493	structural molecule activity conferring elasticity
0.41	GO:0051371	muscle alpha-actinin binding
0.40	GO:0004725	protein tyrosine phosphatase activity
0.39	GO:0051015	actin filament binding
0.33	GO:0016874	ligase activity

0.49	GO:0030018	Z disc
0.40	GO:0005859	muscle myosin complex
0.40	GO:0031430	M band
0.34	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.40

GO:0004725

tr|T1G0K1|T1G0K1_HELRO
Uncharacterized protein
Search

0.64	Vesicle-associated membrane protein 2

0.69	GO:0016192	vesicle-mediated transport
0.46	GO:0097480	establishment of synaptic vesicle localization
0.46	GO:0099504	synaptic vesicle cycle
0.46	GO:0007269	neurotransmitter secretion
0.44	GO:0043134	regulation of hindgut contraction
0.44	GO:1903540	establishment of protein localization to postsynaptic membrane
0.44	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels
0.43	GO:0099637	neurotransmitter receptor transport
0.43	GO:0061951	establishment of protein localization to plasma membrane
0.43	GO:0030421	defecation

0.44	GO:0000149	SNARE binding
0.41	GO:0005516	calmodulin binding
0.40	GO:0005543	phospholipid binding
0.40	GO:0005484	SNAP receptor activity

0.46	GO:0030141	secretory granule
0.46	GO:0008021	synaptic vesicle
0.45	GO:0099501	exocytic vesicle membrane
0.44	GO:0031201	SNARE complex
0.42	GO:0005802	trans-Golgi network
0.41	GO:0048471	perinuclear region of cytoplasm
0.41	GO:0043005	neuron projection
0.41	GO:0048786	presynaptic active zone
0.41	GO:0000322	storage vacuole
0.38	GO:0005886	plasma membrane

tr|T1G0K2|T1G0K2_HELRO
Uncharacterized protein
Search

tr|T1G0K3|T1G0K3_HELRO
Uncharacterized protein
Search

0.60	GO:0007165	signal transduction
0.40	GO:0033563	dorsal/ventral axon guidance
0.35	GO:0040018	positive regulation of multicellular organism growth
0.34	GO:0010171	body morphogenesis
0.34	GO:0042157	lipoprotein metabolic process
0.34	GO:0006869	lipid transport

0.39	GO:0050839	cell adhesion molecule binding
0.36	GO:0030507	spectrin binding
0.34	GO:0008289	lipid binding

0.39	GO:0016328	lateral plasma membrane
0.33	GO:0005576	extracellular region
0.32	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

tr|T1G0K4|T1G0K4_HELRO
Uncharacterized protein
Search

tr|T1G0K5|T1G0K5_HELRO
Uncharacterized protein
Search

0.36	Gametogenetin binding protein 2

0.85	GO:0033140	negative regulation of peptidyl-serine phosphorylation of STAT protein
0.84	GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein
0.81	GO:0061099	negative regulation of protein tyrosine kinase activity
0.73	GO:0008285	negative regulation of cell proliferation
0.72	GO:0060716	labyrinthine layer blood vessel development
0.67	GO:0030154	cell differentiation
0.63	GO:0010629	negative regulation of gene expression

0.60	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm

tr|T1G0K6|T1G0K6_HELRO
Uncharacterized protein
Search

COX11

0.54	Cytochrome c oxidase assembly protein ctaG

0.50	GO:0033132	negative regulation of glucokinase activity
0.44	GO:0055065	metal ion homeostasis
0.37	GO:0043623	cellular protein complex assembly
0.35	GO:0009060	aerobic respiration
0.35	GO:0007585	respiratory gaseous exchange
0.34	GO:1904960	positive regulation of cytochrome-c oxidase activity
0.33	GO:0019464	glycine decarboxylation via glycine cleavage system
0.33	GO:0043043	peptide biosynthetic process
0.33	GO:1902600	hydrogen ion transmembrane transport
0.33	GO:0022900	electron transport chain

0.72	GO:0005507	copper ion binding
0.34	GO:0005515	protein binding
0.33	GO:0015002	heme-copper terminal oxidase activity
0.33	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.33	GO:0003743	translation initiation factor activity
0.33	GO:0015078	hydrogen ion transmembrane transporter activity
0.33	GO:0009055	electron transfer activity
0.33	GO:0003735	structural constituent of ribosome
0.32	GO:0016740	transferase activity

0.42	GO:0005739	mitochondrion
0.39	GO:0043234	protein complex
0.37	GO:0031967	organelle envelope
0.37	GO:0031090	organelle membrane
0.37	GO:0000313	organellar ribosome
0.35	GO:0043233	organelle lumen
0.33	GO:0005960	glycine cleavage complex
0.30	GO:0016021	integral component of membrane

0.33

EC:1.9.3

GO:0016676

tr|T1G0K7|T1G0K7_HELRO
Uncharacterized protein
Search

0.64	Mechanosensory protein 2

0.36

GO:0005887

integral component of plasma membrane

tr|T1G0K8|T1G0K8_HELRO
SUMO-conjugating enzyme
Search

0.52	Ubiquitin-conjugating enzyme

0.81	GO:0016925	protein sumoylation
0.43	GO:0030721	spectrosome organization
0.43	GO:0035207	negative regulation of hemocyte proliferation
0.43	GO:0035172	hemocyte proliferation
0.43	GO:0045614	negative regulation of plasmatocyte differentiation
0.43	GO:0035203	regulation of lamellocyte differentiation
0.42	GO:0007352	zygotic specification of dorsal/ventral axis
0.42	GO:0045751	negative regulation of Toll signaling pathway
0.42	GO:0016321	female meiosis chromosome segregation
0.41	GO:0008354	germ cell migration

0.83	GO:0019789	SUMO transferase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0044388	small protein activating enzyme binding
0.42	GO:0061659	ubiquitin-like protein ligase activity
0.39	GO:0031072	heat shock protein binding
0.39	GO:0016874	ligase activity
0.39	GO:0008134	transcription factor binding
0.39	GO:0031625	ubiquitin protein ligase binding

0.40	GO:0000940	condensed chromosome outer kinetochore
0.40	GO:0000780	condensed nuclear chromosome, centromeric region
0.35	GO:1990356	sumoylated E2 ligase complex
0.34	GO:0016605	PML body
0.34	GO:0005737	cytoplasm
0.33	GO:1990234	transferase complex
0.30	GO:0031224	intrinsic component of membrane

0.39	EC:6	GO:0016874
0.38	KEGG:R03876	GO:0004842

tr|T1G0K9|T1G0K9_HELRO
Uncharacterized protein
Search

RSPH9

0.77	radial spoke head protein 9 homolog

0.84	GO:0035082	axoneme assembly
0.84	GO:0003341	cilium movement

tr|T1G0L0|T1G0L0_HELRO
Uncharacterized protein
Search

SF1

0.54	Splicing factor 1

0.75	GO:0000398	mRNA splicing, via spliceosome
0.46	GO:0033327	Leydig cell differentiation
0.45	GO:0030575	nuclear body organization
0.45	GO:0030238	male sex determination
0.45	GO:0050810	regulation of steroid biosynthetic process
0.38	GO:0000413	protein peptidyl-prolyl isomerization
0.38	GO:0048662	negative regulation of smooth muscle cell proliferation
0.37	GO:0006457	protein folding
0.34	GO:0060041	retina development in camera-type eye
0.33	GO:0006351	transcription, DNA-templated

0.85	GO:0045131	pre-mRNA branch point binding
0.63	GO:0008270	zinc ion binding
0.41	GO:0042802	identical protein binding
0.38	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.33	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.33	GO:0046983	protein dimerization activity

0.43	GO:0016604	nuclear body
0.42	GO:0005681	spliceosomal complex
0.33	GO:0089701	U2AF
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.38

GO:0003755

tr|T1G0L1|T1G0L1_HELRO
Uncharacterized protein
Search

0.10	MAP/microtubule affinity-regulating kinase 3 (Fragment)

0.82	GO:0030010	establishment of cell polarity
0.76	GO:0000226	microtubule cytoskeleton organization
0.63	GO:0006468	protein phosphorylation
0.39	GO:0035330	regulation of hippo signaling
0.36	GO:1902532	negative regulation of intracellular signal transduction
0.35	GO:0016477	cell migration
0.35	GO:0030860	regulation of polarized epithelial cell differentiation
0.35	GO:0030709	border follicle cell delamination
0.35	GO:0048699	generation of neurons
0.35	GO:0007318	pole plasm protein localization

0.70	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.37	GO:0050321	tau-protein kinase activity
0.35	GO:0070300	phosphatidic acid binding
0.34	GO:0001786	phosphatidylserine binding
0.34	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.34	GO:0005515	protein binding

0.35	GO:0070062	extracellular exosome
0.35	GO:0045172	germline ring canal
0.35	GO:0061174	type I terminal bouton
0.35	GO:0045169	fusome
0.34	GO:0005886	plasma membrane
0.34	GO:0031594	neuromuscular junction
0.34	GO:0005938	cell cortex
0.33	GO:0015630	microtubule cytoskeleton
0.33	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.70

GO:0004674

tr|T1G0L2|T1G0L2_HELRO
40S ribosomal protein S21
Search

RPS21

0.70	Ribosomal protein S21

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.44	GO:0048542	lymph gland development
0.44	GO:0016072	rRNA metabolic process
0.43	GO:0042254	ribosome biogenesis
0.41	GO:0006417	regulation of translation
0.41	GO:0042127	regulation of cell proliferation
0.39	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic

0.64	GO:0003735	structural constituent of ribosome
0.46	GO:0047485	protein N-terminus binding
0.41	GO:0043022	ribosome binding
0.33	GO:0035091	phosphatidylinositol binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0003723	RNA binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005840	ribosome
0.46	GO:0005844	polysome
0.44	GO:0044445	cytosolic part
0.39	GO:0044446	intracellular organelle part
0.34	GO:0005791	rough endoplasmic reticulum
0.33	GO:0098562	cytoplasmic side of membrane
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0043233	organelle lumen
0.32	GO:0005634	nucleus

tr|T1G0L3|T1G0L3_HELRO
Uncharacterized protein
Search

0.63	GO:0006468	protein phosphorylation
0.46	GO:0035023	regulation of Rho protein signal transduction
0.42	GO:0065009	regulation of molecular function
0.38	GO:0051726	regulation of cell cycle
0.37	GO:0018209	peptidyl-serine modification
0.37	GO:0000435	positive regulation of transcription from RNA polymerase II promoter by galactose
0.37	GO:0060258	negative regulation of filamentous growth
0.37	GO:2000242	negative regulation of reproductive process
0.37	GO:0048523	negative regulation of cellular process
0.37	GO:0018210	peptidyl-threonine modification

0.64	GO:0004672	protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.46	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.35	GO:0060089	molecular transducer activity
0.34	GO:0030246	carbohydrate binding
0.34	GO:0005509	calcium ion binding
0.32	GO:0043565	sequence-specific DNA binding

0.36	GO:0005634	nucleus
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0043234	protein complex
0.34	GO:0044446	intracellular organelle part
0.33	GO:1902554	serine/threonine protein kinase complex
0.33	GO:0000428	DNA-directed RNA polymerase complex
0.33	GO:0005886	plasma membrane
0.33	GO:0000793	condensed chromosome
0.32	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

tr|T1G0L4|T1G0L4_HELRO
Uncharacterized protein
Search

0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:0010468	regulation of gene expression
0.36	GO:0009405	pathogenesis
0.34	GO:0097659	nucleic acid-templated transcription
0.34	GO:0010467	gene expression
0.34	GO:0034645	cellular macromolecule biosynthetic process

0.51	GO:0003676	nucleic acid binding
0.39	GO:0046872	metal ion binding
0.35	GO:0003700	DNA binding transcription factor activity

0.39	GO:0005634	nucleus
0.30	GO:0044425	membrane part

tr|T1G0L5|T1G0L5_HELRO
Uncharacterized protein
Search

0.64	Glucose-dependent insulinotropic receptor

0.36	GO:0070647	protein modification by small protein conjugation or removal
0.34	GO:0006508	proteolysis
0.33	GO:0007218	neuropeptide signaling pathway
0.33	GO:0006313	transposition, DNA-mediated
0.33	GO:0015074	DNA integration
0.32	GO:0006468	protein phosphorylation
0.32	GO:0006351	transcription, DNA-templated
0.32	GO:0006355	regulation of transcription, DNA-templated

0.35	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.35	GO:0017056	structural constituent of nuclear pore
0.34	GO:0004842	ubiquitin-protein transferase activity
0.34	GO:0008080	N-acetyltransferase activity
0.33	GO:0004983	neuropeptide Y receptor activity
0.33	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor
0.33	GO:0043565	sequence-specific DNA binding
0.33	GO:0008270	zinc ion binding
0.33	GO:0003700	DNA binding transcription factor activity
0.32	GO:0004222	metalloendopeptidase activity

0.35	GO:0005643	nuclear pore
0.32	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.34	EC:2.3.1	GO:0008080
0.34	KEGG:R03876	GO:0004842

tr|T1G0L6|T1G0L6_HELRO
Uncharacterized protein
Search

0.55	GO:0055085	transmembrane transport
0.45	GO:0006817	phosphate ion transport
0.38	GO:1905852	positive regulation of backward locomotion
0.38	GO:0061096	negative regulation of turning behavior involved in mating
0.37	GO:0043051	regulation of pharyngeal pumping
0.37	GO:0035249	synaptic transmission, glutamatergic
0.37	GO:0006972	hyperosmotic response
0.36	GO:0008344	adult locomotory behavior
0.36	GO:0009612	response to mechanical stimulus
0.35	GO:0010035	response to inorganic substance

0.46	GO:0015114	phosphate ion transmembrane transporter activity
0.35	GO:0008378	galactosyltransferase activity
0.34	GO:0015293	symporter activity
0.33	GO:0008233	peptidase activity

0.35	GO:0030672	synaptic vesicle membrane
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.35

GO:0008378

tr|T1G0L7|T1G0L7_HELRO
Uncharacterized protein
Search

IDI1

0.47	Isopentenyl-diphosphate delta-isomerase

0.71	GO:0008299	isoprenoid biosynthetic process
0.44	GO:0045338	farnesyl diphosphate metabolic process
0.44	GO:0008654	phospholipid biosynthetic process
0.40	GO:0046490	isopentenyl diphosphate metabolic process
0.39	GO:0006695	cholesterol biosynthetic process
0.39	GO:0050993	dimethylallyl diphosphate metabolic process
0.35	GO:0045540	regulation of cholesterol biosynthetic process

0.81	GO:0004452	isopentenyl-diphosphate delta-isomerase activity
0.51	GO:0016787	hydrolase activity
0.34	GO:0046872	metal ion binding
0.33	GO:0008080	N-acetyltransferase activity

0.42	GO:0005777	peroxisome
0.34	GO:0005829	cytosol
0.33	GO:0009507	chloroplast
0.30	GO:0016020	membrane

0.81	EC:5.3.3.2	GO:0004452
0.81	KEGG:R01123	GO:0004452

tr|T1G0L8|T1G0L8_HELRO
Uncharacterized protein
Search

0.10	Pyruvate dehydrogenase [acetyl-transferring]-phosphatase 2, mitochondrial

0.72	GO:0006470	protein dephosphorylation
0.35	GO:0060964	regulation of gene silencing by miRNA
0.35	GO:0000086	G2/M transition of mitotic cell cycle
0.34	GO:0006342	chromatin silencing
0.34	GO:1904668	positive regulation of ubiquitin protein ligase activity
0.34	GO:0009617	response to bacterium
0.34	GO:0006306	DNA methylation
0.33	GO:0006777	Mo-molybdopterin cofactor biosynthetic process
0.33	GO:0055114	oxidation-reduction process

0.77	GO:0004722	protein serine/threonine phosphatase activity
0.52	GO:0046872	metal ion binding
0.35	GO:0051019	mitogen-activated protein kinase binding
0.34	GO:0097027	ubiquitin-protein transferase activator activity
0.34	GO:0010997	anaphase-promoting complex binding
0.33	GO:0016491	oxidoreductase activity
0.32	GO:0003677	DNA binding

0.34	GO:0005634	nucleus
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.33

GO:0016491

tr|T1G0L9|T1G0L9_HELRO
Uncharacterized protein
Search

0.76	GO:0015991	ATP hydrolysis coupled proton transport
0.38	GO:0006368	transcription elongation from RNA polymerase II promoter
0.37	GO:0016570	histone modification
0.36	GO:0043413	macromolecule glycosylation
0.36	GO:0009101	glycoprotein biosynthetic process

0.81	GO:0046961	proton-transporting ATPase activity, rotational mechanism
0.72	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism
0.36	GO:0008378	galactosyltransferase activity
0.34	GO:0003677	DNA binding

0.81	GO:0033180	proton-transporting V-type ATPase, V1 domain
0.52	GO:0033181	plasma membrane proton-transporting V-type ATPase complex
0.38	GO:0016593	Cdc73/Paf1 complex
0.36	GO:0000139	Golgi membrane
0.30	GO:0016021	integral component of membrane

0.36

GO:0008378

tr|T1G0M0|T1G0M0_HELRO
Uncharacterized protein
Search

SGSM2

0.60	Small G protein signaling modulator 2

0.75	GO:0043547	positive regulation of GTPase activity
0.45	GO:0031338	regulation of vesicle fusion
0.41	GO:0046907	intracellular transport
0.41	GO:0034613	cellular protein localization
0.40	GO:0015031	protein transport
0.38	GO:0048193	Golgi vesicle transport

0.76	GO:0005096	GTPase activator activity
0.45	GO:0017137	Rab GTPase binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0003676	nucleic acid binding

0.40	GO:0012505	endomembrane system
0.39	GO:0042470	melanosome
0.34	GO:0030659	cytoplasmic vesicle membrane
0.34	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|T1G0M1|T1G0M1_HELRO
Uncharacterized protein
Search

0.44	BolA family transcriptional regulator

0.53	GO:0010039	response to iron ion
0.49	GO:0036086	positive regulation of transcription from RNA polymerase II promoter in response to iron ion starvation
0.49	GO:1903026	negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding
0.49	GO:0051220	cytoplasmic sequestering of protein
0.45	GO:0071248	cellular response to metal ion
0.45	GO:0006879	cellular iron ion homeostasis
0.44	GO:0000122	negative regulation of transcription by RNA polymerase II
0.42	GO:0006979	response to oxidative stress
0.39	GO:0008299	isoprenoid biosynthetic process
0.39	GO:0051301	cell division

0.60	GO:0016758	transferase activity, transferring hexosyl groups
0.43	GO:0051537	2 iron, 2 sulfur cluster binding
0.43	GO:0000062	fatty-acyl-CoA binding
0.42	GO:0004496	mevalonate kinase activity
0.42	GO:0019706	protein-cysteine S-palmitoyltransferase activity
0.36	GO:0030554	adenyl nucleotide binding
0.36	GO:0032555	purine ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005515	protein binding

0.62	GO:0005789	endoplasmic reticulum membrane
0.48	GO:0005829	cytosol
0.44	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.60	EC:2.4.1	GO:0016758
0.42	KEGG:R02245	GO:0004496

tr|T1G0M2|T1G0M2_HELRO
Uncharacterized protein
Search

RIOK3

0.94	Serine/threonine-protein kinase RIO3

0.63	GO:0006468	protein phosphorylation
0.55	GO:1990786	cellular response to dsDNA
0.54	GO:0039534	negative regulation of MDA-5 signaling pathway
0.53	GO:0032463	negative regulation of protein homooligomerization
0.52	GO:0032728	positive regulation of interferon-beta production
0.52	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling
0.51	GO:0098586	cellular response to virus
0.51	GO:0071359	cellular response to dsRNA
0.50	GO:0045089	positive regulation of innate immune response
0.48	GO:0030490	maturation of SSU-rRNA

0.70	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0089720	caspase binding
0.34	GO:0004725	protein tyrosine phosphatase activity
0.34	GO:0046872	metal ion binding

0.50	GO:0030688	preribosome, small subunit precursor
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.70

GO:0004674

tr|T1G0M3|T1G0M3_HELRO
Uncharacterized protein
Search

TTLL10

0.91	Tubulin tyrosine ligase like 10

0.60	GO:0006464	cellular protein modification process
0.36	GO:0097724	sperm flagellum movement
0.36	GO:0060294	cilium movement involved in cell motility
0.36	GO:0007288	sperm axoneme assembly
0.36	GO:0003351	epithelial cilium movement
0.33	GO:0006259	DNA metabolic process
0.32	GO:0006364	rRNA processing
0.32	GO:0006974	cellular response to DNA damage stimulus
0.32	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.32	GO:0034654	nucleobase-containing compound biosynthetic process

0.40	GO:0016874	ligase activity
0.40	GO:0032559	adenyl ribonucleotide binding
0.39	GO:0008144	drug binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0004379	glycylpeptide N-tetradecanoyltransferase activity
0.33	GO:0003887	DNA-directed DNA polymerase activity
0.32	GO:0004518	nuclease activity
0.31	GO:0003700	DNA binding transcription factor activity
0.31	GO:0003677	DNA binding

0.36	GO:0005930	axoneme
0.35	GO:0005874	microtubule
0.34	GO:0019013	viral nucleocapsid
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.31	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.40

GO:0016874

tr|T1G0M4|T1G0M4_HELRO
Uncharacterized protein
Search

RGS5

0.82	Regulator of G protein signaling 8

0.64	GO:0043547	positive regulation of GTPase activity
0.59	GO:0007186	G-protein coupled receptor signaling pathway
0.45	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.42	GO:0035556	intracellular signal transduction
0.42	GO:0043051	regulation of pharyngeal pumping
0.41	GO:0032094	response to food
0.41	GO:0046662	regulation of oviposition
0.41	GO:0002119	nematode larval development
0.40	GO:0040013	negative regulation of locomotion
0.40	GO:0050804	modulation of chemical synaptic transmission

0.65	GO:0005096	GTPase activator activity
0.43	GO:0004871	signal transducer activity
0.36	GO:0005515	protein binding

0.55	GO:0005829	cytosol
0.50	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.50	GO:1905360	GTPase complex
0.49	GO:0005654	nucleoplasm
0.44	GO:0098797	plasma membrane protein complex
0.39	GO:0043005	neuron projection
0.30	GO:0031224	intrinsic component of membrane

tr|T1G0M5|T1G0M5_HELRO
Uncharacterized protein
Search

0.29	Zinc finger protein ubi-d4 A

0.60	GO:0016573	histone acetylation
0.59	GO:0006334	nucleosome assembly
0.47	GO:1903506	regulation of nucleic acid-templated transcription
0.47	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.46	GO:0010468	regulation of gene expression
0.45	GO:1990823	response to leukemia inhibitory factor
0.44	GO:0048513	animal organ development
0.43	GO:1902680	positive regulation of RNA biosynthetic process
0.43	GO:0071345	cellular response to cytokine stimulus
0.43	GO:1902679	negative regulation of RNA biosynthetic process

0.61	GO:0004402	histone acetyltransferase activity
0.54	GO:0046872	metal ion binding
0.48	GO:0003676	nucleic acid binding
0.46	GO:0003713	transcription coactivator activity
0.43	GO:0008134	transcription factor binding
0.34	GO:0032403	protein complex binding
0.33	GO:0004476	mannose-6-phosphate isomerase activity
0.32	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.32	GO:0046983	protein dimerization activity
0.32	GO:0003700	DNA binding transcription factor activity

0.59	GO:0000785	chromatin
0.56	GO:0044815	DNA packaging complex
0.55	GO:0032993	protein-DNA complex
0.54	GO:0070776	MOZ/MORF histone acetyltransferase complex
0.47	GO:0044454	nuclear chromosome part
0.47	GO:0097458	neuron part
0.44	GO:1904949	ATPase complex
0.38	GO:0005829	cytosol
0.38	GO:0005813	centrosome
0.37	GO:0016605	PML body

0.61

GO:0004402

tr|T1G0M6|T1G0M6_HELRO
Uncharacterized protein
Search

tr|T1G0M7|T1G0M7_HELRO
Uncharacterized protein
Search

0.27	Cardioacceleratory peptide receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.52	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol
0.42	GO:0035587	purinergic receptor signaling pathway
0.35	GO:2000293	negative regulation of defecation
0.35	GO:0098508	endothelial to hematopoietic transition
0.35	GO:1903999	negative regulation of eating behavior
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation
0.35	GO:0060013	righting reflex
0.34	GO:0042755	eating behavior
0.34	GO:0070374	positive regulation of ERK1 and ERK2 cascade

0.79	GO:0005000	vasopressin receptor activity
0.65	GO:0008188	neuropeptide receptor activity
0.43	GO:0001609	G-protein coupled adenosine receptor activity
0.38	GO:0004985	opioid receptor activity
0.35	GO:0042277	peptide binding
0.35	GO:0004996	thyroid-stimulating hormone receptor activity
0.33	GO:0004952	dopamine neurotransmitter receptor activity
0.33	GO:0008502	melatonin receptor activity
0.33	GO:0004964	luteinizing hormone receptor activity
0.33	GO:0038036	sphingosine-1-phosphate receptor activity

0.45	GO:0005886	plasma membrane
0.33	GO:0005737	cytoplasm
0.32	GO:0070062	extracellular exosome
0.32	GO:0043005	neuron projection
0.30	GO:0016021	integral component of membrane

0.32

GO:0004252

tr|T1G0M8|T1G0M8_HELRO
Uncharacterized protein
Search

tr|T1G0M9|T1G0M9_HELRO
Anoctamin
Search

0.66

Anoctamin

0.60	GO:0061588	calcium activated phospholipid scrambling
0.47	GO:0050965	detection of temperature stimulus involved in sensory perception of pain
0.45	GO:1902476	chloride transmembrane transport
0.45	GO:0050829	defense response to Gram-negative bacterium

0.68	GO:0046983	protein dimerization activity
0.49	GO:0061778	intracellular chloride channel activity
0.48	GO:0097603	temperature-gated ion channel activity
0.44	GO:0005247	voltage-gated chloride channel activity
0.39	GO:0017128	phospholipid scramblase activity

0.34	GO:0005886	plasma membrane
0.32	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

tr|T1G0N0|T1G0N0_HELRO
Uncharacterized protein
Search

0.50	GO:0009443	pyridoxal 5'-phosphate salvage
0.41	GO:0016310	phosphorylation
0.39	GO:1901031	regulation of response to reactive oxygen species
0.38	GO:0006886	intracellular protein transport
0.38	GO:0061025	membrane fusion
0.38	GO:0016192	vesicle-mediated transport

0.50	GO:0008478	pyridoxal kinase activity
0.40	GO:0005484	SNAP receptor activity

0.63	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.50

EC:2.7.1.35

GO:0008478

tr|T1G0N1|T1G0N1_HELRO
Uncharacterized protein
Search

0.54	GO:0055085	transmembrane transport
0.43	GO:0006820	anion transport
0.39	GO:0071702	organic substance transport
0.37	GO:0009437	carnitine metabolic process
0.36	GO:0015696	ammonium transport
0.35	GO:0042221	response to chemical
0.33	GO:0006629	lipid metabolic process
0.33	GO:0055114	oxidation-reduction process
0.33	GO:0007186	G-protein coupled receptor signaling pathway

0.55	GO:0022857	transmembrane transporter activity
0.35	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.35	GO:0020037	heme binding
0.34	GO:0005506	iron ion binding
0.34	GO:0008081	phosphoric diester hydrolase activity
0.33	GO:0008528	G-protein coupled peptide receptor activity

0.47	GO:0016323	basolateral plasma membrane
0.40	GO:0005887	integral component of plasma membrane
0.34	GO:0009705	plant-type vacuole membrane

0.35

GO:0016705

tr|T1G0N2|T1G0N2_HELRO
Uncharacterized protein
Search

tr|T1G0N3|T1G0N3_HELRO
Uncharacterized protein
Search

UBA2

0.91	SUMO-activating enzyme subunit

0.81	GO:0016925	protein sumoylation
0.34	GO:0043085	positive regulation of catalytic activity

0.85	GO:0019948	SUMO activating enzyme activity
0.71	GO:0016881	acid-amino acid ligase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0046872	metal ion binding
0.53	GO:0044388	small protein activating enzyme binding
0.51	GO:0032183	SUMO binding
0.50	GO:0044390	ubiquitin-like protein conjugating enzyme binding
0.46	GO:0046982	protein heterodimerization activity

0.54	GO:0031510	SUMO activating enzyme complex
0.44	GO:0005654	nucleoplasm
0.36	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.71

EC:6.3.2

GO:0016881

tr|T1G0N4|T1G0N4_HELRO
Uncharacterized protein
Search

0.48	GO:0006030	chitin metabolic process
0.40	GO:0006508	proteolysis
0.40	GO:0006898	receptor-mediated endocytosis
0.39	GO:0007186	G-protein coupled receptor signaling pathway
0.39	GO:0032501	multicellular organismal process
0.38	GO:0030509	BMP signaling pathway
0.38	GO:0048856	anatomical structure development
0.38	GO:0060828	regulation of canonical Wnt signaling pathway
0.36	GO:1904447	folic acid import across plasma membrane
0.36	GO:0003006	developmental process involved in reproduction

0.62	GO:0005509	calcium ion binding
0.47	GO:0008061	chitin binding
0.43	GO:0004252	serine-type endopeptidase activity
0.40	GO:0004872	receptor activity
0.38	GO:0004871	signal transducer activity
0.35	GO:0017147	Wnt-protein binding
0.34	GO:0003729	mRNA binding
0.33	GO:0003735	structural constituent of ribosome

0.44	GO:0005576	extracellular region
0.39	GO:0043235	receptor complex
0.38	GO:0098590	plasma membrane region
0.37	GO:0045177	apical part of cell
0.37	GO:0098589	membrane region
0.36	GO:0005794	Golgi apparatus
0.35	GO:0005903	brush border
0.35	GO:0009897	external side of plasma membrane
0.35	GO:0030139	endocytic vesicle
0.35	GO:0030425	dendrite

0.43

GO:0004252

tr|T1G0N5|T1G0N5_HELRO
Uncharacterized protein
Search

tr|T1G0N6|T1G0N6_HELRO
Uncharacterized protein
Search

0.40	Truncated microsomal omega-3 fatty acid desaturase

0.63	GO:0006629	lipid metabolic process
0.50	GO:0055114	oxidation-reduction process
0.37	GO:0072330	monocarboxylic acid biosynthetic process
0.35	GO:0040002	collagen and cuticulin-based cuticle development
0.35	GO:0009409	response to cold
0.34	GO:0045087	innate immune response
0.34	GO:0000003	reproduction

0.73	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
0.41	GO:0016720	delta12-fatty acid dehydrogenase activity
0.37	GO:0042389	omega-3 fatty acid desaturase activity

0.38	GO:0009941	chloroplast envelope
0.37	GO:0042170	plastid membrane
0.32	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

0.73	EC:1.14.19	GO:0016717
0.41	KEGG:R05740	GO:0016720

tr|T1G0N7|T1G0N7_HELRO
Uncharacterized protein
Search

tr|T1G0N8|T1G0N8_HELRO
Uncharacterized protein
Search

0.54	GO:0007155	cell adhesion
0.50	GO:0033334	fin morphogenesis
0.49	GO:0071711	basement membrane organization
0.40	GO:0021682	nerve maturation
0.39	GO:0008050	female courtship behavior
0.39	GO:0048468	cell development
0.39	GO:0032989	cellular component morphogenesis
0.39	GO:0048036	central complex development
0.39	GO:0031034	myosin filament assembly
0.39	GO:0035011	melanotic encapsulation of foreign target

0.50	GO:0005509	calcium ion binding
0.39	GO:0097493	structural molecule activity conferring elasticity
0.39	GO:0051371	muscle alpha-actinin binding
0.39	GO:0004672	protein kinase activity
0.39	GO:0051015	actin filament binding
0.39	GO:0008307	structural constituent of muscle
0.38	GO:0017022	myosin binding
0.37	GO:0030554	adenyl nucleotide binding
0.36	GO:0097367	carbohydrate derivative binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding

0.40	GO:0031672	A band
0.40	GO:0031674	I band
0.39	GO:0005919	pleated septate junction
0.39	GO:0035230	cytoneme
0.39	GO:0005859	muscle myosin complex
0.38	GO:0016328	lateral plasma membrane
0.38	GO:0030175	filopodium
0.38	GO:0005604	basement membrane
0.38	GO:0005923	bicellular tight junction
0.37	GO:0005938	cell cortex

0.35

GO:0004725

tr|T1G0N9|T1G0N9_HELRO
Uncharacterized protein
Search

SH3GL1

0.88	Endophilin-A

0.71	GO:0006897	endocytosis
0.38	GO:0072318	clathrin coat disassembly
0.37	GO:0036465	synaptic vesicle recycling
0.37	GO:0099003	vesicle-mediated transport in synapse

0.40	GO:0016746	transferase activity, transferring acyl groups
0.38	GO:0045296	cadherin binding
0.37	GO:0042802	identical protein binding
0.34	GO:0008289	lipid binding

0.49	GO:0005737	cytoplasm
0.36	GO:0045202	synapse
0.35	GO:0002102	podosome
0.34	GO:0030054	cell junction
0.34	GO:0097708	intracellular vesicle
0.34	GO:0098805	whole membrane
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0042995	cell projection
0.33	GO:0012505	endomembrane system
0.30	GO:0044425	membrane part

0.40

EC:2.3

GO:0016746

tr|T1G0P0|T1G0P0_HELRO
Uncharacterized protein
Search

0.66	G/T mismatch-specific thymine DNA glycosylase

0.65	GO:0006281	DNA repair
0.51	GO:1902544	regulation of DNA N-glycosylase activity
0.50	GO:0035562	negative regulation of chromatin binding
0.48	GO:0032091	negative regulation of protein binding
0.48	GO:0080111	DNA demethylation
0.46	GO:0040029	regulation of gene expression, epigenetic
0.45	GO:0000122	negative regulation of transcription by RNA polymerase II
0.44	GO:0009790	embryo development
0.34	GO:0016569	covalent chromatin modification
0.34	GO:0009223	pyrimidine deoxyribonucleotide catabolic process

0.74	GO:0019104	DNA N-glycosylase activity
0.49	GO:0031404	chloride ion binding
0.49	GO:0032183	SUMO binding
0.49	GO:0005080	protein kinase C binding
0.48	GO:0043621	protein self-association
0.48	GO:0003690	double-stranded DNA binding
0.47	GO:0031402	sodium ion binding
0.46	GO:0001104	RNA polymerase II transcription cofactor activity
0.45	GO:0042803	protein homodimerization activity
0.41	GO:0000287	magnesium ion binding

0.48	GO:0016605	PML body
0.38	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.74

EC:3.2.2

GO:0019104

tr|T1G0P1|T1G0P1_HELRO
Uncharacterized protein
Search

0.60	Glucose-dependent insulinotropic receptor

0.36	GO:0070647	protein modification by small protein conjugation or removal
0.34	GO:0006508	proteolysis
0.33	GO:0007218	neuropeptide signaling pathway
0.33	GO:0006313	transposition, DNA-mediated
0.33	GO:0015074	DNA integration
0.32	GO:0006351	transcription, DNA-templated
0.32	GO:0006468	protein phosphorylation
0.32	GO:0006355	regulation of transcription, DNA-templated

0.35	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.35	GO:0017056	structural constituent of nuclear pore
0.34	GO:0004842	ubiquitin-protein transferase activity
0.34	GO:0008080	N-acetyltransferase activity
0.33	GO:0004983	neuropeptide Y receptor activity
0.33	GO:0043565	sequence-specific DNA binding
0.33	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor
0.33	GO:0008270	zinc ion binding
0.33	GO:0003700	DNA binding transcription factor activity
0.32	GO:0004222	metalloendopeptidase activity

0.35	GO:0005643	nuclear pore
0.32	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.34	EC:2.3.1	GO:0008080
0.34	KEGG:R03876	GO:0004842

tr|T1G0P2|T1G0P2_HELRO
Uncharacterized protein
Search

0.40	Transcriptional regulator BolA

0.56	GO:0051301	cell division
0.47	GO:0043085	positive regulation of catalytic activity
0.40	GO:0001731	formation of translation preinitiation complex
0.40	GO:0006446	regulation of translational initiation
0.38	GO:0016192	vesicle-mediated transport
0.37	GO:0015031	protein transport
0.37	GO:0015992	proton transport
0.36	GO:0016310	phosphorylation
0.35	GO:0055085	transmembrane transport

0.48	GO:0008047	enzyme activator activity
0.45	GO:0000062	fatty-acyl-CoA binding
0.41	GO:0052689	carboxylic ester hydrolase activity
0.39	GO:0003951	NAD+ kinase activity
0.39	GO:0016853	isomerase activity
0.38	GO:0003743	translation initiation factor activity
0.37	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.37	GO:0005515	protein binding

0.49	GO:0009570	chloroplast stroma
0.42	GO:0005739	mitochondrion
0.41	GO:0016471	vacuolar proton-transporting V-type ATPase complex
0.40	GO:0005576	extracellular region
0.40	GO:0016282	eukaryotic 43S preinitiation complex
0.40	GO:0033290	eukaryotic 48S preinitiation complex
0.39	GO:0005852	eukaryotic translation initiation factor 3 complex
0.30	GO:0031224	intrinsic component of membrane

0.41	EC:3.1.1 EC:3.1.1.1	GO:0052689
0.41	KEGG:R00630	GO:0052689

tr|T1G0P3|T1G0P3_HELRO
Uncharacterized protein
Search

0.58	Cyclic nucleotide gated non-selective ion channel alpha 3

0.57	GO:0034220	ion transmembrane transport
0.42	GO:0071804	cellular potassium ion transport
0.41	GO:0019935	cyclic-nucleotide-mediated signaling
0.41	GO:0042391	regulation of membrane potential
0.35	GO:0034765	regulation of ion transmembrane transport
0.32	GO:0006468	protein phosphorylation

0.66	GO:0005216	ion channel activity
0.44	GO:0022836	gated channel activity
0.42	GO:0015079	potassium ion transmembrane transporter activity
0.34	GO:0004692	cGMP-dependent protein kinase activity

0.43	GO:0017071	intracellular cyclic nucleotide activated cation channel complex
0.38	GO:0005887	integral component of plasma membrane
0.33	GO:0005622	intracellular

0.34

EC:2.7.11.12

GO:0004692

tr|T1G0P4|T1G0P4_HELRO
Uncharacterized protein
Search

0.60	Nicotinic acetylcholine receptor subunit

0.70	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.43	GO:0006511	ubiquitin-dependent protein catabolic process
0.42	GO:1902656	calcium ion import into cytosol
0.41	GO:0098739	import across plasma membrane
0.40	GO:0007274	neuromuscular synaptic transmission
0.39	GO:0006937	regulation of muscle contraction
0.38	GO:0040012	regulation of locomotion
0.37	GO:0035094	response to nicotine
0.36	GO:0030534	adult behavior

0.75	GO:0005230	extracellular ligand-gated ion channel activity
0.73	GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential
0.70	GO:0099600	transmembrane receptor activity
0.68	GO:0022835	transmitter-gated channel activity
0.67	GO:0140135	mechanosensitive cation channel activity
0.45	GO:0031625	ubiquitin protein ligase binding
0.35	GO:0042166	acetylcholine binding
0.34	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.33	GO:0008146	sulfotransferase activity
0.32	GO:0046872	metal ion binding

0.70	GO:0045211	postsynaptic membrane
0.66	GO:0030054	cell junction
0.38	GO:0043005	neuron projection
0.37	GO:0031461	cullin-RING ubiquitin ligase complex
0.36	GO:0005892	acetylcholine-gated channel complex

0.34

GO:0004114

tr|T1G0P5|T1G0P5_HELRO
Uncharacterized protein
Search

0.66	T-box transcription factor TBX2

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.49	GO:1901211	negative regulation of cardiac chamber formation
0.49	GO:1901208	negative regulation of heart looping
0.49	GO:0036302	atrioventricular canal development
0.49	GO:0060465	pharynx development
0.48	GO:0007521	muscle cell fate determination
0.48	GO:0060596	mammary placode formation

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.43	GO:0001067	regulatory region nucleic acid binding
0.35	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.43	GO:0005667	transcription factor complex
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|T1G0P6|T1G0P6_HELRO
Uncharacterized protein
Search

SSNA1

0.95	Sjoegren syndrome nuclear autoantigen 1

0.87	GO:0060830	ciliary receptor clustering involved in smoothened signaling pathway
0.83	GO:0042073	intraciliary transport
0.44	GO:0097711	ciliary basal body-plasma membrane docking
0.42	GO:0000086	G2/M transition of mitotic cell cycle
0.42	GO:0010389	regulation of G2/M transition of mitotic cell cycle

0.73

GO:0042802

identical protein binding

0.82	GO:0036064	ciliary basal body
0.77	GO:0005813	centrosome
0.42	GO:0005634	nucleus
0.39	GO:0005829	cytosol
0.36	GO:0005886	plasma membrane

tr|T1G0P7|T1G0P7_HELRO
Uncharacterized protein
Search

PNCA

0.46	Bifunctional pyrazinamidase/nicotinamidase

0.36	GO:0006769	nicotinamide metabolic process
0.33	GO:1904523	regulation of DNA amplification
0.33	GO:2000279	negative regulation of DNA biosynthetic process
0.33	GO:0000183	chromatin silencing at rDNA
0.33	GO:0001302	replicative cell aging
0.33	GO:0006348	chromatin silencing at telomere

0.47	GO:0008936	nicotinamidase activity
0.33	GO:0005509	calcium ion binding

0.33	GO:0000781	chromosome, telomeric region
0.32	GO:0005777	peroxisome
0.32	GO:0005634	nucleus

0.47

EC:3.5.1.19

GO:0008936

tr|T1G0P8|T1G0P8_HELRO
Uncharacterized protein
Search

0.90	Protein N-lysine methyltransferase METTL21A isoform B

0.63	GO:0032259	methylation
0.39	GO:0018205	peptidyl-lysine modification
0.39	GO:0008213	protein alkylation

0.63	GO:0008168	methyltransferase activity
0.36	GO:0140096	catalytic activity, acting on a protein

0.34	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

0.63

GO:0008168

tr|T1G0P9|T1G0P9_HELRO
Uncharacterized protein
Search

MOCS2

0.50	Molybdopterin synthase catalytic subunit

0.70	GO:0006777	Mo-molybdopterin cofactor biosynthetic process
0.43	GO:0032324	molybdopterin cofactor biosynthetic process
0.40	GO:0016573	histone acetylation
0.40	GO:0006338	chromatin remodeling
0.33	GO:0006413	translational initiation
0.32	GO:0055114	oxidation-reduction process

0.73	GO:0030366	molybdopterin synthase activity
0.41	GO:0004402	histone acetyltransferase activity
0.34	GO:0042802	identical protein binding
0.34	GO:0050464	nitrate reductase (NADPH) activity
0.33	GO:0003743	translation initiation factor activity
0.33	GO:1901265	nucleoside phosphate binding
0.33	GO:0036094	small molecule binding

0.66	GO:0019008	molybdopterin synthase complex
0.59	GO:0005829	cytosol
0.45	GO:0016607	nuclear speck
0.42	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex
0.42	GO:0005700	polytene chromosome
0.34	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.73

EC:2.8.1.12

GO:0030366

tr|T1G0Q0|T1G0Q0_HELRO
Uncharacterized protein
Search

0.81	Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein (Fragment)

0.53	GO:1903506	regulation of nucleic acid-templated transcription
0.39	GO:0033567	DNA replication, Okazaki fragment processing
0.38	GO:1902680	positive regulation of RNA biosynthetic process
0.38	GO:0010468	regulation of gene expression
0.37	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:0006401	RNA catabolic process
0.36	GO:0010605	negative regulation of macromolecule metabolic process
0.35	GO:0016071	mRNA metabolic process
0.35	GO:0043244	regulation of protein complex disassembly
0.35	GO:0051276	chromosome organization

0.76	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.50	GO:0004386	helicase activity
0.40	GO:0046872	metal ion binding
0.39	GO:0043142	single-stranded DNA-dependent ATPase activity
0.39	GO:0017108	5'-flap endonuclease activity
0.38	GO:0003676	nucleic acid binding
0.37	GO:0030554	adenyl nucleotide binding
0.36	GO:0032555	purine ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding

0.36	GO:0005844	polysome
0.36	GO:0010494	cytoplasmic stress granule
0.36	GO:0005634	nucleus
0.34	GO:0031379	RNA-directed RNA polymerase complex
0.33	GO:0000775	chromosome, centromeric region
0.32	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.33

EC:2.1.1.63

GO:0003908

tr|T1G0Q1|T1G0Q1_HELRO
Uncharacterized protein
Search

PBDC1

0.97	Polysaccharide biosynthesis domain containing 1

0.38

GO:0006913

nucleocytoplasmic transport

0.47

GO:0016872

intramolecular lyase activity

0.47	GO:0005737	cytoplasm
0.39	GO:0005643	nuclear pore
0.30	GO:0044425	membrane part

0.47

EC:5.5

GO:0016872

tr|T1G0Q2|T1G0Q2_HELRO
Uncharacterized protein
Search

0.37	Sodium-dependent phosphate transporter

0.55	GO:0055085	transmembrane transport
0.42	GO:0006817	phosphate ion transport
0.36	GO:1905852	positive regulation of backward locomotion
0.36	GO:0061094	regulation of turning behavior involved in mating
0.36	GO:1902436	negative regulation of male mating behavior
0.36	GO:0043051	regulation of pharyngeal pumping
0.35	GO:0035249	synaptic transmission, glutamatergic
0.35	GO:0009628	response to abiotic stimulus
0.35	GO:0048190	wing disc dorsal/ventral pattern formation
0.35	GO:0008344	adult locomotory behavior

0.43	GO:0015114	phosphate ion transmembrane transporter activity
0.34	GO:0005509	calcium ion binding
0.34	GO:0015293	symporter activity
0.33	GO:0015136	sialic acid transmembrane transporter activity
0.33	GO:0008378	galactosyltransferase activity
0.32	GO:0008233	peptidase activity

0.34	GO:0005887	integral component of plasma membrane
0.33	GO:0005765	lysosomal membrane
0.33	GO:0031410	cytoplasmic vesicle
0.32	GO:0005829	cytosol
0.32	GO:0005739	mitochondrion

0.33

GO:0008378

tr|T1G0Q3|T1G0Q3_HELRO
Uncharacterized protein
Search

MYLK4

0.56	Myosin light chain kinase

0.63	GO:0006468	protein phosphorylation
0.50	GO:0018210	peptidyl-threonine modification
0.48	GO:0061061	muscle structure development
0.47	GO:0018209	peptidyl-serine modification
0.46	GO:0032971	regulation of muscle filament sliding
0.46	GO:0002528	regulation of vascular permeability involved in acute inflammatory response
0.46	GO:0048738	cardiac muscle tissue development
0.45	GO:0030154	cell differentiation
0.45	GO:0009653	anatomical structure morphogenesis
0.44	GO:0007274	neuromuscular synaptic transmission

0.64	GO:0004672	protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0005516	calmodulin binding
0.35	GO:0019901	protein kinase binding
0.34	GO:0032027	myosin light chain binding
0.34	GO:0097493	structural molecule activity conferring elasticity
0.34	GO:0051371	muscle alpha-actinin binding

0.41	GO:0015629	actin cytoskeleton
0.38	GO:0031672	A band
0.38	GO:0005634	nucleus
0.34	GO:0070062	extracellular exosome
0.34	GO:0005829	cytosol
0.33	GO:0043195	terminal bouton
0.33	GO:0043197	dendritic spine
0.33	GO:0030018	Z disc
0.33	GO:0014069	postsynaptic density
0.33	GO:0030906	retromer, cargo-selective complex

tr|T1G0Q4|T1G0Q4_HELRO
Uncharacterized protein
Search

0.51	GO:0043966	histone H3 acetylation
0.40	GO:0045893	positive regulation of transcription, DNA-templated
0.36	GO:0034968	histone lysine methylation

0.54	GO:0046872	metal ion binding
0.45	GO:0042393	histone binding
0.45	GO:0043994	histone acetyltransferase activity (H3-K23 specific)
0.39	GO:0003676	nucleic acid binding
0.36	GO:0018024	histone-lysine N-methyltransferase activity

0.52	GO:0070776	MOZ/MORF histone acetyltransferase complex
0.45	GO:0016607	nuclear speck
0.39	GO:0005829	cytosol
0.36	GO:0005886	plasma membrane

0.36

EC:2.1.1.43

GO:0018024

tr|T1G0Q5|T1G0Q5_HELRO
Uncharacterized protein
Search

ABCE1

0.87	RNase L inhibitor

0.48	GO:0060702	negative regulation of endoribonuclease activity
0.43	GO:0000054	ribosomal subunit export from nucleus
0.43	GO:0006413	translational initiation
0.41	GO:0006415	translational termination
0.40	GO:0043524	negative regulation of neuron apoptotic process
0.40	GO:0070481	nuclear-transcribed mRNA catabolic process, non-stop decay
0.40	GO:0016049	cell growth
0.35	GO:0006436	tryptophanyl-tRNA aminoacylation
0.34	GO:0032790	ribosome disassembly
0.34	GO:0015716	organic phosphonate transport

0.61	GO:0016887	ATPase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0060698	endoribonuclease inhibitor activity
0.47	GO:0043024	ribosomal small subunit binding
0.40	GO:0031369	translation initiation factor binding
0.38	GO:0005506	iron ion binding
0.35	GO:0004830	tryptophan-tRNA ligase activity
0.34	GO:0015604	organic phosphonate transmembrane transporter activity

0.45	GO:0005852	eukaryotic translation initiation factor 3 complex
0.42	GO:0005829	cytosol
0.40	GO:0005739	mitochondrion
0.34	GO:0009331	glycerol-3-phosphate dehydrogenase complex
0.30	GO:0016020	membrane

0.61	EC:3.6.1.3	GO:0016887
0.34	KEGG:R00842	GO:0004367

tr|T1G0Q6|T1G0Q6_HELRO
Uncharacterized protein
Search

0.68	Regulatory-associated protein of mTOR (inferred by orthology to a human protein)

0.82	GO:0031929	TOR signaling
0.46	GO:0008361	regulation of cell size
0.45	GO:0007562	eclosion
0.44	GO:0040008	regulation of growth
0.44	GO:0001934	positive regulation of protein phosphorylation
0.44	GO:0008340	determination of adult lifespan
0.44	GO:0035096	larval midgut cell programmed cell death
0.43	GO:1904397	negative regulation of neuromuscular junction development
0.43	GO:0051964	negative regulation of synapse assembly
0.42	GO:0003006	developmental process involved in reproduction

0.41

GO:0030674

protein binding, bridging

0.83	GO:0031931	TORC1 complex
0.34	GO:0005776	autophagosome
0.30	GO:0016020	membrane

tr|T1G0Q7|T1G0Q7_HELRO
Uncharacterized protein
Search

0.50	Zinc finger MYM-type protein 1

0.36	GO:0016310	phosphorylation
0.35	GO:0046080	dUTP metabolic process
0.34	GO:0006431	methionyl-tRNA aminoacylation
0.34	GO:0006313	transposition, DNA-mediated
0.33	GO:0015074	DNA integration

0.68	GO:0046983	protein dimerization activity
0.36	GO:0016301	kinase activity
0.35	GO:0004170	dUTP diphosphatase activity
0.34	GO:0004825	methionine-tRNA ligase activity
0.34	GO:0008270	zinc ion binding
0.33	GO:0003676	nucleic acid binding
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.35	GO:0000812	Swr1 complex
0.35	GO:0035267	NuA4 histone acetyltransferase complex
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.35	EC:3.6.1.23	GO:0004170
0.35	KEGG:R02100	GO:0004170

tr|T1G0Q8|T1G0Q8_HELRO
Uncharacterized protein
Search

0.70	GO:0007275	multicellular organism development
0.70	GO:0009966	regulation of signal transduction
0.60	GO:0120036	plasma membrane bounded cell projection organization
0.59	GO:0048468	cell development
0.44	GO:0090287	regulation of cellular response to growth factor stimulus
0.41	GO:0009653	anatomical structure morphogenesis

0.39	GO:0030658	transport vesicle membrane
0.35	GO:0005886	plasma membrane

tr|T1G0Q9|T1G0Q9_HELRO
Uncharacterized protein
Search

0.19	Transposase

0.34	GO:0035556	intracellular signal transduction
0.33	GO:0006413	translational initiation
0.33	GO:0015074	DNA integration
0.32	GO:0000055	ribosomal large subunit export from nucleus
0.32	GO:0042273	ribosomal large subunit biogenesis
0.32	GO:0030036	actin cytoskeleton organization

0.50	GO:0003676	nucleic acid binding
0.37	GO:0046872	metal ion binding
0.31	GO:0016787	hydrolase activity

0.32	GO:0005622	intracellular
0.30	GO:0016020	membrane

0.31

GO:0016787

tr|T1G0R0|T1G0R0_HELRO
Uncharacterized protein
Search

PNCA

0.51	Bifunctional pyrazinamidase/nicotinamidase

0.35	GO:1904523	regulation of DNA amplification
0.35	GO:2000279	negative regulation of DNA biosynthetic process
0.35	GO:0000183	chromatin silencing at rDNA
0.34	GO:0001302	replicative cell aging
0.34	GO:0006348	chromatin silencing at telomere
0.34	GO:0006769	nicotinamide metabolic process

0.48

GO:0008936

nicotinamidase activity

0.34	GO:0000781	chromosome, telomeric region
0.34	GO:0005777	peroxisome
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.48

EC:3.5.1.19

GO:0008936

tr|T1G0R1|T1G0R1_HELRO
Uncharacterized protein
Search

VBP1

0.73	Prefoldin subunit 3

0.68	GO:0006457	protein folding
0.46	GO:0007021	tubulin complex assembly
0.42	GO:0007017	microtubule-based process

0.43

GO:0015631

tubulin binding

0.79	GO:0016272	prefoldin complex
0.46	GO:0005844	polysome
0.45	GO:0005829	cytosol
0.40	GO:0043227	membrane-bounded organelle
0.39	GO:0043229	intracellular organelle
0.30	GO:0031224	intrinsic component of membrane

tr|T1G0R2|T1G0R2_HELRO
Uncharacterized protein
Search

0.44	Glycosyl-phosphatidylinositol-linked carbonic anhydrase

0.68	GO:0006730	one-carbon metabolic process
0.38	GO:0015670	carbon dioxide transport
0.37	GO:0097369	sodium ion import
0.37	GO:0042539	hypotonic salinity response
0.36	GO:0006885	regulation of pH
0.36	GO:0071466	cellular response to xenobiotic stimulus
0.35	GO:0015701	bicarbonate transport

0.73	GO:0004089	carbonate dehydratase activity
0.60	GO:0008270	zinc ion binding
0.35	GO:0004064	arylesterase activity

0.41	GO:0031225	anchored component of membrane
0.36	GO:0005886	plasma membrane
0.35	GO:0030667	secretory granule membrane
0.35	GO:0005903	brush border
0.35	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.35	GO:0005791	rough endoplasmic reticulum
0.35	GO:0070062	extracellular exosome
0.34	GO:0045177	apical part of cell
0.34	GO:0005802	trans-Golgi network
0.34	GO:0048471	perinuclear region of cytoplasm

0.73

GO:0004089

tr|T1G0R3|T1G0R3_HELRO
Uncharacterized protein
Search

0.82

GO:0051209

release of sequestered calcium ion into cytosol

0.84	GO:0005219	ryanodine-sensitive calcium-release channel activity
0.49	GO:0005509	calcium ion binding

0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1G0R4|T1G0R4_HELRO
Uncharacterized protein
Search

0.90	Nicotinic acetylcholine receptor beta subunit

0.79	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.45	GO:0007271	synaptic transmission, cholinergic

0.82	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0099600	transmembrane receptor activity
0.34	GO:0008146	sulfotransferase activity

0.79	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.35	GO:0005892	acetylcholine-gated channel complex

0.34

EC:2.8.2

GO:0008146

tr|T1G0R5|T1G0R5_HELRO
Uncharacterized protein
Search

0.61	Nuclear receptor subfamily 2 group E member 1

0.75	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.47	GO:0035271	ring gland development
0.46	GO:0001748	optic lobe placode development
0.46	GO:0002121	inter-male aggressive behavior
0.46	GO:0014019	neuroblast development
0.46	GO:0007362	terminal region determination

0.76	GO:0003707	steroid hormone receptor activity
0.65	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.38	GO:0004824	lysine-tRNA ligase activity
0.38	GO:0001012	RNA polymerase II regulatory region DNA binding
0.37	GO:0003690	double-stranded DNA binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005634	nucleus
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.38

EC:6.1.1.6

GO:0004824

tr|T1G0R6|T1G0R6_HELRO
Uncharacterized protein
Search

0.56	GO:0001522	pseudouridine synthesis
0.51	GO:0016180	snRNA processing
0.47	GO:0007165	signal transduction

0.56	GO:0009982	pseudouridine synthase activity
0.48	GO:0003723	RNA binding
0.46	GO:0032550	purine ribonucleoside binding
0.46	GO:0019001	guanyl nucleotide binding
0.41	GO:0032555	purine ribonucleotide binding
0.41	GO:0035639	purine ribonucleoside triphosphate binding

0.51	GO:0032039	integrator complex
0.30	GO:0016020	membrane

0.56

EC:5.4.99.12

GO:0009982

tr|T1G0R7|T1G0R7_HELRO
Uncharacterized protein
Search

RPL39

0.84	Angiomotin like 2

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.40	GO:0007283	spermatogenesis
0.38	GO:0002227	innate immune response in mucosa
0.37	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.37	GO:0019731	antibacterial humoral response
0.37	GO:0050830	defense response to Gram-positive bacterium
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

0.64	GO:0003735	structural constituent of ribosome
0.40	GO:0003723	RNA binding
0.34	GO:0005515	protein binding

0.61	GO:0005840	ribosome
0.45	GO:0044445	cytosolic part
0.40	GO:0044446	intracellular organelle part
0.36	GO:0005615	extracellular space
0.34	GO:0005844	polysome
0.34	GO:0043233	organelle lumen
0.33	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

tr|T1G0R8|T1G0R8_HELRO
Uncharacterized protein
Search

GNPAT

0.77	Dihydroxyacetone phosphate acyltransferase

0.64	GO:0044255	cellular lipid metabolic process
0.56	GO:0046504	glycerol ether biosynthetic process
0.46	GO:0008610	lipid biosynthetic process
0.38	GO:0019637	organophosphate metabolic process
0.37	GO:0030913	paranodal junction assembly
0.37	GO:0006796	phosphate-containing compound metabolic process
0.37	GO:0021587	cerebellum morphogenesis
0.37	GO:0007416	synapse assembly
0.35	GO:0061024	membrane organization
0.34	GO:0055114	oxidation-reduction process

0.74	GO:0008374	O-acyltransferase activity
0.47	GO:0016407	acetyltransferase activity
0.38	GO:0080019	fatty-acyl-CoA reductase (alcohol-forming) activity
0.37	GO:0016290	palmitoyl-CoA hydrolase activity
0.37	GO:0102965	alcohol-forming fatty acyl-CoA reductase activity
0.35	GO:0005102	receptor binding
0.35	GO:0102420	sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity

0.51	GO:0005777	peroxisome
0.43	GO:0031903	microbody membrane
0.33	GO:0030117	membrane coat
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.74

EC:2.3.1

GO:0008374

tr|T1G0R9|T1G0R9_HELRO
Uncharacterized protein
Search

tr|T1G0S0|T1G0S0_HELRO
Uncharacterized protein
Search

POLD2

0.90	LOW QUALITY PROTEIN: DNA polymerase delta subunit 2

0.67	GO:0071897	DNA biosynthetic process
0.66	GO:0006260	DNA replication
0.47	GO:0022616	DNA strand elongation
0.42	GO:0006974	cellular response to DNA damage stimulus
0.34	GO:0000723	telomere maintenance
0.34	GO:0019725	cellular homeostasis
0.34	GO:0006266	DNA ligation
0.34	GO:0051606	detection of stimulus
0.34	GO:0042593	glucose homeostasis
0.34	GO:0022402	cell cycle process

0.71	GO:0003887	DNA-directed DNA polymerase activity
0.55	GO:0003677	DNA binding
0.34	GO:0005536	glucose binding
0.33	GO:0004396	hexokinase activity
0.33	GO:0005515	protein binding
0.33	GO:0005509	calcium ion binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.51	GO:0043625	delta DNA polymerase complex
0.47	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.71

EC:2.7.7.7

GO:0003887

tr|T1G0S1|T1G0S1_HELRO
Tubby-like protein
Search

0.90	Tubby like protein 1

0.76	GO:0060434	bronchus morphogenesis
0.75	GO:0021914	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning
0.74	GO:1901621	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
0.74	GO:0061512	protein localization to cilium
0.74	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning
0.73	GO:0048702	embryonic neurocranium morphogenesis
0.73	GO:0061548	ganglion development
0.71	GO:0031076	embryonic camera-type eye development
0.70	GO:0042733	embryonic digit morphogenesis
0.69	GO:0001843	neural tube closure

0.71	GO:0035091	phosphatidylinositol binding
0.63	GO:0032403	protein complex binding
0.59	GO:0019899	enzyme binding
0.42	GO:0003700	DNA binding transcription factor activity
0.38	GO:0043565	sequence-specific DNA binding

0.71	GO:0005929	cilium
0.71	GO:0030991	intraciliary transport particle A
0.67	GO:0032838	plasma membrane bounded cell projection cytoplasm
0.61	GO:0005730	nucleolus
0.58	GO:0044430	cytoskeletal part
0.48	GO:0005886	plasma membrane
0.40	GO:0005576	extracellular region
0.39	GO:0005829	cytosol
0.37	GO:0030425	dendrite
0.37	GO:0030424	axon

tr|T1G0S2|T1G0S2_HELRO
Uncharacterized protein
Search

tr|T1G0S3|T1G0S3_HELRO
Uncharacterized protein
Search

tr|T1G0S4|T1G0S4_HELRO
Uncharacterized protein
Search

0.66	Phosphatidylinositol-binding clathrin assembly protein LAP

0.83	GO:0048268	clathrin coat assembly
0.35	GO:0048488	synaptic vesicle endocytosis
0.35	GO:2000370	positive regulation of clathrin-dependent endocytosis
0.34	GO:0042331	phototaxis
0.34	GO:0007268	chemical synaptic transmission
0.34	GO:0048489	synaptic vesicle transport
0.34	GO:0006420	arginyl-tRNA aminoacylation
0.33	GO:0099643	signal release from synapse
0.33	GO:0006898	receptor-mediated endocytosis
0.33	GO:0006836	neurotransmitter transport

0.84	GO:0005545	1-phosphatidylinositol binding
0.81	GO:0030276	clathrin binding
0.34	GO:0004814	arginine-tRNA ligase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.80	GO:0030136	clathrin-coated vesicle
0.34	GO:0045202	synapse
0.34	GO:0005905	clathrin-coated pit
0.33	GO:0005794	Golgi apparatus
0.33	GO:0097458	neuron part
0.30	GO:0016021	integral component of membrane

0.34

EC:6.1.1.19

GO:0004814

tr|T1G0S5|T1G0S5_HELRO
Uncharacterized protein
Search

DNAI1

0.94	Dynein axonemal intermediate chain 1

0.78	GO:0003341	cilium movement
0.72	GO:0008286	insulin receptor signaling pathway
0.71	GO:0007368	determination of left/right symmetry
0.68	GO:0007507	heart development
0.67	GO:0036158	outer dynein arm assembly
0.54	GO:0007605	sensory perception of sound
0.43	GO:0030317	flagellated sperm motility

0.68	GO:0045504	dynein heavy chain binding
0.67	GO:0045503	dynein light chain binding
0.66	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed

0.69	GO:0036157	outer dynein arm
0.66	GO:0005813	centrosome
0.44	GO:0005874	microtubule
0.30	GO:0031224	intrinsic component of membrane

0.66

EC:3.6.4.4

GO:0008574

tr|T1G0S6|T1G0S6_HELRO
Uncharacterized protein
Search

tr|T1G0S7|T1G0S7_HELRO
Uncharacterized protein
Search

AP1S2

0.57	AP complex subunit sigma

0.68	GO:0006886	intracellular protein transport
0.67	GO:0016192	vesicle-mediated transport
0.37	GO:0060612	adipose tissue development
0.36	GO:0008542	visual learning
0.36	GO:0036465	synaptic vesicle recycling
0.36	GO:0050885	neuromuscular process controlling balance
0.36	GO:0045444	fat cell differentiation
0.35	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.34	GO:0045176	apical protein localization
0.33	GO:0050690	regulation of defense response to virus by virus

0.69	GO:0008565	protein transporter activity
0.34	GO:0005515	protein binding

0.73	GO:0030117	membrane coat
0.39	GO:0043227	membrane-bounded organelle
0.38	GO:0005905	clathrin-coated pit
0.38	GO:0043229	intracellular organelle
0.36	GO:0098793	presynapse
0.35	GO:0044422	organelle part
0.34	GO:0098797	plasma membrane protein complex
0.33	GO:0005829	cytosol

tr|T1G0S8|T1G0S8_HELRO
Uncharacterized protein
Search

PSMD1

0.89	26S proteasome non-ATPase regulatory subunit 1

0.78	GO:0042176	regulation of protein catabolic process
0.69	GO:0050790	regulation of catalytic activity
0.44	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation
0.35	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0070498	interleukin-1-mediated signaling pathway

0.70	GO:0030234	enzyme regulator activity
0.40	GO:0004175	endopeptidase activity
0.34	GO:0005515	protein binding

0.73	GO:1905369	endopeptidase complex
0.59	GO:0043234	protein complex
0.45	GO:0005622	intracellular
0.38	GO:0043227	membrane-bounded organelle
0.36	GO:0043230	extracellular organelle
0.35	GO:0005615	extracellular space
0.33	GO:0012505	endomembrane system
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0044422	organelle part
0.30	GO:0016020	membrane

tr|T1G0S9|T1G0S9_HELRO
Uncharacterized protein
Search

BLOC1S1

0.94	Biogenesis of lysosomal organelles complex 1 subunit 1

0.48	GO:0048490	anterograde synaptic vesicle transport
0.45	GO:0016197	endosomal transport
0.40	GO:0032418	lysosome localization
0.39	GO:0031175	neuron projection development
0.39	GO:0018394	peptidyl-lysine acetylation
0.36	GO:0009060	aerobic respiration
0.36	GO:0048753	pigment granule organization
0.35	GO:0060155	platelet dense granule organization
0.34	GO:0008355	olfactory learning
0.34	GO:0007274	neuromuscular synaptic transmission

0.34	GO:0005515	protein binding
0.34	GO:0008478	pyridoxal kinase activity

0.84	GO:0031083	BLOC-1 complex
0.47	GO:1904115	axon cytoplasm
0.45	GO:0005758	mitochondrial intermembrane space
0.44	GO:0005769	early endosome
0.44	GO:0005759	mitochondrial matrix
0.41	GO:0099078	BORC complex
0.40	GO:0005765	lysosomal membrane
0.35	GO:0070062	extracellular exosome
0.33	GO:0045202	synapse
0.30	GO:0016021	integral component of membrane

0.34

EC:2.7.1.35

GO:0008478

tr|T1G0T0|T1G0T0_HELRO
Uncharacterized protein
Search

0.59	Leucine-rich repeats and immunoglobulin-like domains 3

0.57

GO:0032474

otolith morphogenesis

0.38	GO:0030659	cytoplasmic vesicle membrane
0.37	GO:0005615	extracellular space
0.35	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

tr|T1G0T1|T1G0T1_HELRO
Uncharacterized protein
Search

PXMP4

0.94	Peroxisomal membrane protein 4

0.33	GO:0006351	transcription, DNA-templated
0.33	GO:2001141	regulation of RNA biosynthetic process
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.33	GO:0005515	protein binding
0.33	GO:0003700	DNA binding transcription factor activity
0.32	GO:0003677	DNA binding

0.66	GO:0031903	microbody membrane
0.65	GO:0044439	peroxisomal part
0.34	GO:0005667	transcription factor complex
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

tr|T1G0T2|T1G0T2_HELRO
Uncharacterized protein
Search

0.57	GO:0009932	cell tip growth
0.49	GO:0010051	xylem and phloem pattern formation
0.49	GO:0010087	phloem or xylem histogenesis
0.48	GO:0009965	leaf morphogenesis
0.46	GO:0009733	response to auxin
0.45	GO:0043547	positive regulation of GTPase activity
0.43	GO:0006897	endocytosis
0.38	GO:0055114	oxidation-reduction process

0.64	GO:0019706	protein-cysteine S-palmitoyltransferase activity
0.59	GO:0000035	acyl binding
0.45	GO:0035091	phosphatidylinositol binding
0.45	GO:0005096	GTPase activator activity
0.42	GO:0005515	protein binding
0.38	GO:0016491	oxidoreductase activity
0.38	GO:0046872	metal ion binding

0.54	GO:0031410	cytoplasmic vesicle
0.53	GO:0005802	trans-Golgi network
0.42	GO:0005829	cytosol
0.38	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.64

GO:0019706

tr|T1G0T3|T1G0T3_HELRO
Uncharacterized protein
Search

UBE2R2

0.60	Ubiquitin-conjugating enzyme

0.51	GO:0070936	protein K48-linked ubiquitination
0.48	GO:0006513	protein monoubiquitination
0.46	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.39	GO:0043951	negative regulation of cAMP-mediated signaling
0.39	GO:0035458	cellular response to interferon-beta
0.33	GO:0051301	cell division
0.33	GO:0006281	DNA repair
0.33	GO:0090305	nucleic acid phosphodiester bond hydrolysis

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0061631	ubiquitin conjugating enzyme activity
0.46	GO:0031625	ubiquitin protein ligase binding
0.45	GO:0061630	ubiquitin protein ligase activity
0.33	GO:0004518	nuclease activity
0.33	GO:0016874	ligase activity

0.37	GO:0016607	nuclear speck
0.37	GO:0005737	cytoplasm

0.33

GO:0004518

tr|T1G0T4|T1G0T4_HELRO
Uncharacterized protein
Search

0.50	GO:0031398	positive regulation of protein ubiquitination
0.48	GO:0016567	protein ubiquitination
0.48	GO:0006511	ubiquitin-dependent protein catabolic process
0.48	GO:0051457	maintenance of protein location in nucleus
0.47	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage
0.46	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator
0.46	GO:0051438	regulation of ubiquitin-protein transferase activity
0.46	GO:0016925	protein sumoylation
0.45	GO:0010498	proteasomal protein catabolic process
0.44	GO:0051347	positive regulation of transferase activity

0.49	GO:0044547	DNA topoisomerase binding
0.48	GO:0004842	ubiquitin-protein transferase activity
0.47	GO:0003823	antigen binding
0.47	GO:0016874	ligase activity
0.46	GO:0019789	SUMO transferase activity
0.45	GO:0061659	ubiquitin-like protein ligase activity
0.45	GO:0008270	zinc ion binding
0.44	GO:0002039	p53 binding
0.42	GO:0042803	protein homodimerization activity
0.41	GO:0016853	isomerase activity

0.48	GO:0000151	ubiquitin ligase complex
0.48	GO:0032391	photoreceptor connecting cilium
0.47	GO:0016605	PML body
0.46	GO:0036064	ciliary basal body
0.46	GO:0000930	gamma-tubulin complex
0.46	GO:0005814	centriole
0.46	GO:0016607	nuclear speck
0.45	GO:0000922	spindle pole
0.40	GO:0005829	cytosol
0.34	GO:0005868	cytoplasmic dynein complex

0.47	EC:6	GO:0016874
0.48	KEGG:R03876	GO:0004842

tr|T1G0T5|T1G0T5_HELRO
Uncharacterized protein
Search

LARGE

0.70	Like-glycosyltransferase (Fragment)

0.50	GO:0035269	protein O-linked mannosylation
0.41	GO:0043403	skeletal muscle tissue regeneration
0.41	GO:0046716	muscle cell cellular homeostasis
0.40	GO:0060538	skeletal muscle organ development
0.34	GO:0006688	glycosphingolipid biosynthetic process
0.34	GO:0006044	N-acetylglucosamine metabolic process
0.33	GO:0006457	protein folding
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.63	GO:0016757	transferase activity, transferring glycosyl groups
0.42	GO:0030145	manganese ion binding
0.33	GO:0005515	protein binding
0.32	GO:0043565	sequence-specific DNA binding
0.32	GO:0003700	DNA binding transcription factor activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.43	GO:0005794	Golgi apparatus
0.36	GO:0098588	bounding membrane of organelle
0.36	GO:0031984	organelle subcompartment
0.33	GO:0031301	integral component of organelle membrane
0.32	GO:0005634	nucleus

0.63

GO:0016757

tr|T1G0T6|T1G0T6_HELRO
Uncharacterized protein
Search

0.64	Phosphoethanolamine N-methyltransferase 1

0.81	GO:0006656	phosphatidylcholine biosynthetic process
0.63	GO:0032259	methylation
0.39	GO:0042425	choline biosynthetic process
0.37	GO:0010183	pollen tube guidance
0.37	GO:0009860	pollen tube growth
0.37	GO:0048528	post-embryonic root development
0.37	GO:0009555	pollen development
0.33	GO:0006468	protein phosphorylation

0.85	GO:0000234	phosphoethanolamine N-methyltransferase activity
0.37	GO:0052667	phosphomethylethanolamine N-methyltransferase activity
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.35	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.85	EC:2.1.1.103	GO:0000234
0.85	KEGG:R02037	GO:0000234

tr|T1G0T7|T1G0T7_HELRO
Uncharacterized protein
Search

LSM5

0.89	LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated

0.46	GO:0000956	nuclear-transcribed mRNA catabolic process
0.45	GO:0000398	mRNA splicing, via spliceosome
0.33	GO:0000413	protein peptidyl-prolyl isomerization

0.40	GO:0003723	RNA binding
0.34	GO:0005515	protein binding
0.33	GO:0003755	peptidyl-prolyl cis-trans isomerase activity

0.59	GO:0030529	intracellular ribonucleoprotein complex
0.49	GO:1990726	Lsm1-7-Pat1 complex
0.42	GO:0044428	nuclear part
0.33	GO:0005829	cytosol
0.33	GO:0031974	membrane-enclosed lumen

0.33

GO:0003755

tr|T1G0T8|T1G0T8_HELRO
Uncharacterized protein
Search

0.63	MER proto-oncogene, tyrosine kinase

0.71	GO:0018108	peptidyl-tyrosine phosphorylation
0.61	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.54	GO:0038065	collagen-activated signaling pathway
0.44	GO:0045399	regulation of interleukin-3 biosynthetic process
0.44	GO:0032752	positive regulation of interleukin-3 production
0.44	GO:0045425	positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process
0.44	GO:0002281	macrophage activation involved in immune response
0.44	GO:0071226	cellular response to molecule of fungal origin
0.44	GO:0033008	positive regulation of mast cell activation involved in immune response
0.44	GO:0043366	beta selection

0.72	GO:0004713	protein tyrosine kinase activity
0.61	GO:0019199	transmembrane receptor protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0038064	collagen receptor activity
0.43	GO:0035325	Toll-like receptor binding
0.42	GO:0042169	SH2 domain binding
0.41	GO:0019902	phosphatase binding

0.44	GO:0044459	plasma membrane part
0.43	GO:0032009	early phagosome
0.42	GO:0019814	immunoglobulin complex
0.40	GO:0043235	receptor complex
0.37	GO:0098796	membrane protein complex
0.37	GO:0005634	nucleus
0.36	GO:0098562	cytoplasmic side of membrane
0.36	GO:0019898	extrinsic component of membrane
0.33	GO:0005829	cytosol
0.33	GO:0120114	Sm-like protein family complex

0.72

GO:0004713

tr|T1G0T9|T1G0T9_HELRO
Uncharacterized protein
Search

0.56	N-acetyllactosamine synthase (inferred by orthology to a C. elegans protein)

0.60	GO:0005975	carbohydrate metabolic process
0.44	GO:0006688	glycosphingolipid biosynthetic process
0.43	GO:0007528	neuromuscular junction development
0.43	GO:0008344	adult locomotory behavior
0.41	GO:0006044	N-acetylglucosamine metabolic process
0.37	GO:0045747	positive regulation of Notch signaling pathway
0.36	GO:0006486	protein glycosylation
0.35	GO:0009636	response to toxic substance
0.33	GO:0015698	inorganic anion transport
0.32	GO:0006351	transcription, DNA-templated

0.65	GO:0016757	transferase activity, transferring glycosyl groups
0.42	GO:0140103	catalytic activity, acting on a glycoprotein
0.33	GO:0005452	inorganic anion exchanger activity
0.33	GO:0030246	carbohydrate binding
0.33	GO:0046872	metal ion binding
0.32	GO:0003676	nucleic acid binding
0.32	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.32	GO:0004386	helicase activity
0.32	GO:0001882	nucleoside binding
0.31	GO:0032559	adenyl ribonucleotide binding

0.40	GO:0005794	Golgi apparatus
0.30	GO:0016020	membrane

0.65

GO:0016757

tr|T1G0U0|T1G0U0_HELRO
Uncharacterized protein
Search

RPS28

0.74	40S ribosomal protein S28 (inferred by orthology to a C. elegans protein)

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.44	GO:0000028	ribosomal small subunit assembly
0.41	GO:0016072	rRNA metabolic process
0.37	GO:0035220	wing disc development
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.33	GO:0019083	viral transcription

0.64	GO:0003735	structural constituent of ribosome
0.37	GO:0003723	RNA binding
0.33	GO:0051539	4 iron, 4 sulfur cluster binding
0.33	GO:0003677	DNA binding
0.33	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding
0.32	GO:0016787	hydrolase activity

0.61	GO:0005840	ribosome
0.43	GO:0044445	cytosolic part
0.40	GO:0005844	polysome
0.39	GO:0098556	cytoplasmic side of rough endoplasmic reticulum membrane
0.35	GO:0005634	nucleus
0.34	GO:0070062	extracellular exosome
0.34	GO:0019008	molybdopterin synthase complex
0.33	GO:0043233	organelle lumen
0.33	GO:0005694	chromosome
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016787

tr|T1G0U1|T1G0U1_HELRO
Uncharacterized protein
Search

0.74	GO:0007219	Notch signaling pathway
0.65	GO:0030154	cell differentiation
0.63	GO:0007275	multicellular organism development
0.62	GO:0050793	regulation of developmental process
0.50	GO:0045967	negative regulation of growth rate
0.47	GO:0046579	positive regulation of Ras protein signal transduction
0.47	GO:2001027	negative regulation of endothelial cell chemotaxis
0.46	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.46	GO:0072602	interleukin-4 secretion
0.46	GO:0061419	positive regulation of transcription from RNA polymerase II promoter in response to hypoxia

0.70	GO:0005509	calcium ion binding
0.50	GO:0060089	molecular transducer activity
0.46	GO:0005112	Notch binding
0.45	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.44	GO:0031490	chromatin DNA binding
0.44	GO:0001047	core promoter binding
0.42	GO:0004857	enzyme inhibitor activity
0.42	GO:0046982	protein heterodimerization activity
0.41	GO:0019899	enzyme binding
0.39	GO:0043565	sequence-specific DNA binding

0.46	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex
0.46	GO:0009986	cell surface
0.45	GO:0043235	receptor complex
0.44	GO:0005912	adherens junction
0.44	GO:0016324	apical plasma membrane
0.42	GO:0031410	cytoplasmic vesicle
0.41	GO:0005783	endoplasmic reticulum
0.41	GO:0005634	nucleus
0.38	GO:0070013	intracellular organelle lumen
0.37	GO:0005576	extracellular region

0.34

EC:3.1.1.4

GO:0004623

tr|T1G0U2|T1G0U2_HELRO
Uncharacterized protein
Search

MGAT1

0.90	Mutant N-acetylglucosaminyltransferase I

0.74	GO:0043413	macromolecule glycosylation
0.74	GO:0009101	glycoprotein biosynthetic process
0.60	GO:0036211	protein modification process
0.56	GO:0044267	cellular protein metabolic process
0.51	GO:0006049	UDP-N-acetylglucosamine catabolic process
0.46	GO:0001701	in utero embryonic development
0.34	GO:0006013	mannose metabolic process
0.33	GO:0043039	tRNA aminoacylation
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:0010467	gene expression

0.77	GO:0008375	acetylglucosaminyltransferase activity
0.41	GO:0140103	catalytic activity, acting on a glycoprotein
0.34	GO:0046872	metal ion binding
0.33	GO:0004813	alanine-tRNA ligase activity
0.33	GO:0003676	nucleic acid binding
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.37	GO:0000139	Golgi membrane
0.35	GO:0070062	extracellular exosome
0.34	GO:0005797	Golgi medial cisterna
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.77

GO:0008375

tr|T1G0U3|T1G0U3_HELRO
Uncharacterized protein
Search

0.57

GO:0016310

phosphorylation

0.60

GO:0016301

kinase activity

tr|T1G0U4|T1G0U4_HELRO
Uncharacterized protein
Search

0.55	Glutamate receptor ionotropic, kainate

0.78	GO:0060079	excitatory postsynaptic potential
0.77	GO:0035235	ionotropic glutamate receptor signaling pathway
0.59	GO:0034220	ion transmembrane transport
0.42	GO:0048899	anterior lateral line development
0.41	GO:0048915	posterior lateral line system development
0.41	GO:0014032	neural crest cell development
0.40	GO:0048701	embryonic cranial skeleton morphogenesis
0.38	GO:0007399	nervous system development

0.81	GO:0005234	extracellularly glutamate-gated ion channel activity
0.77	GO:0004970	ionotropic glutamate receptor activity
0.38	GO:0099094	ligand-gated cation channel activity

0.76	GO:0098794	postsynapse
0.75	GO:0097060	synaptic membrane
0.71	GO:0030054	cell junction
0.39	GO:0032281	AMPA glutamate receptor complex
0.35	GO:0043025	neuronal cell body
0.35	GO:0030425	dendrite

tr|T1G0U5|T1G0U5_HELRO
Uncharacterized protein
Search

ECI2

0.62	enoyl-CoA delta isomerase 2, mitochondrial

0.35	GO:0006635	fatty acid beta-oxidation
0.35	GO:0016573	histone acetylation
0.33	GO:0050829	defense response to Gram-negative bacterium
0.32	GO:0016310	phosphorylation

0.49	GO:0000062	fatty-acyl-CoA binding
0.46	GO:0004300	enoyl-CoA hydratase activity
0.45	GO:0016853	isomerase activity
0.36	GO:0005102	receptor binding
0.35	GO:0004402	histone acetyltransferase activity
0.33	GO:0003859	3-hydroxybutyryl-CoA dehydratase activity
0.33	GO:0008776	acetate kinase activity
0.31	GO:0016787	hydrolase activity

0.38	GO:0005634	nucleus
0.38	GO:0005777	peroxisome
0.36	GO:0031907	microbody lumen
0.35	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.46	EC:4.2.1.17	GO:0004300
0.33	KEGG:R03027	GO:0003859

tr|T1G0U6|T1G0U6_HELRO
Uncharacterized protein
Search

tr|T1G0U7|T1G0U7_HELRO
Uncharacterized protein
Search

0.37	Exosporium leader peptide

0.58	GO:1903225	negative regulation of endodermal cell differentiation
0.56	GO:0030199	collagen fibril organization
0.55	GO:0071230	cellular response to amino acid stimulus
0.54	GO:0043588	skin development
0.53	GO:0048592	eye morphogenesis
0.53	GO:0001501	skeletal system development
0.38	GO:0001503	ossification
0.37	GO:0071711	basement membrane organization
0.37	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.37	GO:0007528	neuromuscular junction development

0.71	GO:0005201	extracellular matrix structural constituent
0.55	GO:0046332	SMAD binding
0.44	GO:0042302	structural constituent of cuticle
0.35	GO:0048407	platelet-derived growth factor binding
0.35	GO:0005509	calcium ion binding
0.35	GO:0004867	serine-type endopeptidase inhibitor activity
0.34	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.33	GO:0042393	histone binding
0.32	GO:0004872	receptor activity
0.32	GO:0016887	ATPase activity

0.66	GO:0005581	collagen trimer
0.57	GO:0098644	complex of collagen trimers
0.50	GO:0005615	extracellular space
0.50	GO:0099081	supramolecular polymer
0.42	GO:0005604	basement membrane
0.35	GO:0005788	endoplasmic reticulum lumen
0.35	GO:0031594	neuromuscular junction
0.33	GO:0016514	SWI/SNF complex
0.30	GO:0016020	membrane

0.34

EC:1.2.1

GO:0016620

tr|T1G0U8|T1G0U8_HELRO
Uncharacterized protein
Search

0.65	GO:0007275	multicellular organism development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.45	GO:0006366	transcription by RNA polymerase II
0.44	GO:0007601	visual perception
0.42	GO:1904888	cranial skeletal system development
0.40	GO:0002053	positive regulation of mesenchymal cell proliferation
0.39	GO:0045880	positive regulation of smoothened signaling pathway
0.39	GO:0061448	connective tissue development

0.64	GO:0043565	sequence-specific DNA binding
0.41	GO:0003700	DNA binding transcription factor activity
0.40	GO:0071837	HMG box domain binding
0.38	GO:0001012	RNA polymerase II regulatory region DNA binding
0.38	GO:0001105	RNA polymerase II transcription coactivator activity
0.37	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.35	GO:0005829	cytosol
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0044446	intracellular organelle part

tr|T1G0U9|T1G0U9_HELRO
Uncharacterized protein
Search

0.46	Polyphosphoinositide phosphatase

0.49	GO:0031642	negative regulation of myelination
0.49	GO:0032288	myelin assembly
0.47	GO:0043473	pigmentation
0.46	GO:0007626	locomotory behavior
0.46	GO:0007033	vacuole organization
0.45	GO:0048666	neuron development
0.44	GO:0046488	phosphatidylinositol metabolic process
0.35	GO:0010976	positive regulation of neuron projection development
0.34	GO:0046474	glycerophospholipid biosynthetic process
0.34	GO:0016311	dephosphorylation

0.68	GO:0042578	phosphoric ester hydrolase activity
0.33	GO:0005515	protein binding

0.46	GO:0005811	lipid droplet
0.45	GO:0010008	endosome membrane
0.38	GO:0043231	intracellular membrane-bounded organelle
0.35	GO:0055037	recycling endosome
0.34	GO:0005770	late endosome
0.34	GO:0005769	early endosome
0.33	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0042578

tr|T1G0V0|T1G0V0_HELRO
Uncharacterized protein
Search

0.79	N-terminal kinase protein (Fragment)

0.63	GO:0006468	protein phosphorylation
0.37	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER

0.63	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0045296	cadherin binding

0.37	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.37	GO:0005801	cis-Golgi network
0.37	GO:0030126	COPI vesicle coat
0.35	GO:0005829	cytosol
0.34	GO:0005815	microtubule organizing center
0.30	GO:0016021	integral component of membrane

tr|T1G0V1|T1G0V1_HELRO
Uncharacterized protein
Search

ZC3H15

0.89	Zinc finger CCCH domain-containing protein 15

0.45	GO:0019221	cytokine-mediated signaling pathway
0.33	GO:0015991	ATP hydrolysis coupled proton transport
0.33	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.33	GO:0006754	ATP biosynthetic process

0.54	GO:0046872	metal ion binding
0.46	GO:0045296	cadherin binding
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0032561	guanyl ribonucleotide binding
0.33	GO:0003723	RNA binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0015078	hydrogen ion transmembrane transporter activity

0.44	GO:0005730	nucleolus
0.42	GO:0005829	cytosol
0.33	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)
0.30	GO:0016021	integral component of membrane

tr|T1G0V2|T1G0V2_HELRO
Uncharacterized protein
Search

0.53	Xylose and arabinose reductase

0.53

GO:0055114

oxidation-reduction process

0.54

GO:0016491

oxidoreductase activity

0.54

GO:0016491

tr|T1G0V3|T1G0V3_HELRO
Actin-related protein 2/3 complex subunit 3
Search

ARPC3

0.74	Actin-related protein 2/3 complex subunit 3

0.79	GO:0034314	Arp2/3 complex-mediated actin nucleation
0.38	GO:1990090	cellular response to nerve growth factor stimulus
0.35	GO:0070358	actin polymerization-dependent cell motility
0.35	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.34	GO:0048013	ephrin receptor signaling pathway
0.33	GO:0061024	membrane organization

0.68	GO:0003779	actin binding
0.47	GO:0005200	structural constituent of cytoskeleton
0.46	GO:0032403	protein complex binding

0.78	GO:0005885	Arp2/3 protein complex
0.50	GO:0030027	lamellipodium
0.46	GO:0005737	cytoplasm
0.39	GO:0061850	growth cone leading edge
0.37	GO:0031941	filamentous actin
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

tr|T1G0V4|T1G0V4_HELRO
Uncharacterized protein
Search

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.50	GO:0007399	nervous system development
0.49	GO:0048839	inner ear development
0.46	GO:0030154	cell differentiation
0.46	GO:0007605	sensory perception of sound
0.46	GO:0007626	locomotory behavior
0.45	GO:0120036	plasma membrane bounded cell projection organization
0.42	GO:0072137	condensed mesenchymal cell proliferation
0.42	GO:0048729	tissue morphogenesis
0.42	GO:0007267	cell-cell signaling

0.70	GO:0005509	calcium ion binding
0.39	GO:0004930	G-protein coupled receptor activity
0.37	GO:0050839	cell adhesion molecule binding
0.35	GO:0032403	protein complex binding
0.34	GO:0005057	signal transducer activity, downstream of receptor
0.32	GO:0042803	protein homodimerization activity

0.56	GO:0005886	plasma membrane
0.47	GO:0032420	stereocilium
0.40	GO:0045177	apical part of cell
0.36	GO:0031254	cell trailing edge
0.36	GO:0030054	cell junction
0.36	GO:0045178	basal part of cell
0.35	GO:0030426	growth cone
0.34	GO:0070062	extracellular exosome
0.33	GO:0005622	intracellular
0.33	GO:0005902	microvillus

tr|T1G0V5|T1G0V5_HELRO
Uncharacterized protein
Search

DBI

0.59	Acyl-CoA-binding domain-containing protein 7

0.49	GO:0001300	chronological cell aging
0.49	GO:0042761	very long-chain fatty acid biosynthetic process
0.43	GO:0036151	phosphatidylcholine acyl-chain remodeling
0.33	GO:0006744	ubiquinone biosynthetic process
0.33	GO:0008299	isoprenoid biosynthetic process

0.82	GO:0000062	fatty-acyl-CoA binding
0.38	GO:0046983	protein dimerization activity
0.37	GO:0008289	lipid binding
0.34	GO:0047293	4-hydroxybenzoate nonaprenyltransferase activity
0.34	GO:0002083	4-hydroxybenzoate decaprenyltransferase activity
0.33	GO:0008483	transaminase activity
0.33	GO:0030170	pyridoxal phosphate binding
0.32	GO:0016746	transferase activity, transferring acyl groups
0.32	GO:0016787	hydrolase activity

0.42	GO:0005576	extracellular region
0.35	GO:0005794	Golgi apparatus
0.35	GO:0005783	endoplasmic reticulum
0.33	GO:0005829	cytosol
0.33	GO:0005911	cell-cell junction
0.33	GO:0031305	integral component of mitochondrial inner membrane

0.34

EC:2.5.1.39

GO:0047293

tr|T1G0V6|T1G0V6_HELRO
Uncharacterized protein
Search

0.53	GO:0055114	oxidation-reduction process
0.38	GO:0071407	cellular response to organic cyclic compound
0.37	GO:0071466	cellular response to xenobiotic stimulus
0.36	GO:0070988	demethylation
0.35	GO:0002933	lipid hydroxylation
0.35	GO:0009636	response to toxic substance
0.35	GO:0050665	hydrogen peroxide biosynthetic process
0.34	GO:0031087	deadenylation-independent decapping of nuclear-transcribed mRNA
0.34	GO:0008202	steroid metabolic process
0.34	GO:0009404	toxin metabolic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.65	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.35	GO:0070576	vitamin D 24-hydroxylase activity
0.35	GO:0019825	oxygen binding
0.34	GO:0016829	lyase activity
0.34	GO:0005184	neuropeptide hormone activity
0.34	GO:0008270	zinc ion binding
0.34	GO:0003729	mRNA binding

0.54	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0031090	organelle membrane
0.34	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.68

GO:0016705

tr|T1G0V7|T1G0V7_HELRO
Uncharacterized protein
Search

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.46	GO:0007166	cell surface receptor signaling pathway
0.46	GO:0007186	G-protein coupled receptor signaling pathway
0.45	GO:0048839	inner ear development
0.45	GO:0007605	sensory perception of sound
0.37	GO:0007424	open tracheal system development
0.36	GO:0007399	nervous system development
0.35	GO:0016336	establishment or maintenance of polarity of larval imaginal disc epithelium
0.35	GO:0045317	equator specification
0.35	GO:0090176	microtubule cytoskeleton organization involved in establishment of planar polarity

0.70	GO:0005509	calcium ion binding
0.46	GO:0004930	G-protein coupled receptor activity
0.34	GO:0045296	cadherin binding
0.34	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.34	GO:0004022	alcohol dehydrogenase (NAD) activity

0.56	GO:0005886	plasma membrane
0.46	GO:0032420	stereocilium
0.32	GO:0005622	intracellular
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:2.7.10.1

GO:0004714

tr|T1G0V8|T1G0V8_HELRO
Uncharacterized protein
Search

0.97	Msx2-interacting protein (Fragment)

0.50	GO:0048699	generation of neurons
0.48	GO:0010720	positive regulation of cell development
0.48	GO:0051962	positive regulation of nervous system development
0.48	GO:0000122	negative regulation of transcription by RNA polymerase II
0.47	GO:0048106	establishment of thoracic bristle planar orientation
0.46	GO:0007403	glial cell fate determination
0.45	GO:0048867	stem cell fate determination
0.45	GO:0008586	imaginal disc-derived wing vein morphogenesis
0.45	GO:0007379	segment specification
0.45	GO:0035222	wing disc pattern formation

0.59	GO:0003723	RNA binding
0.50	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.50	GO:0001085	RNA polymerase II transcription factor binding
0.37	GO:0003714	transcription corepressor activity
0.36	GO:0003697	single-stranded DNA binding
0.35	GO:0033904	dextranase activity
0.34	GO:0003700	DNA binding transcription factor activity
0.32	GO:0046872	metal ion binding

0.49	GO:0017053	transcriptional repressor complex
0.45	GO:0005634	nucleus
0.43	GO:0043233	organelle lumen
0.40	GO:0044446	intracellular organelle part
0.37	GO:0070062	extracellular exosome

0.35

EC:3.2.1.11

GO:0033904

tr|T1G0V9|T1G0V9_HELRO
Uncharacterized protein
Search

0.43	GO:0007155	cell adhesion
0.41	GO:0030198	extracellular matrix organization
0.40	GO:0007275	multicellular organism development
0.40	GO:0048646	anatomical structure formation involved in morphogenesis
0.40	GO:0001886	endothelial cell morphogenesis
0.40	GO:2000353	positive regulation of endothelial cell apoptotic process
0.38	GO:0030335	positive regulation of cell migration
0.38	GO:0008284	positive regulation of cell proliferation
0.38	GO:0009405	pathogenesis
0.38	GO:0010951	negative regulation of endopeptidase activity

0.60	GO:0005201	extracellular matrix structural constituent
0.40	GO:0042302	structural constituent of cuticle
0.38	GO:0004867	serine-type endopeptidase inhibitor activity
0.36	GO:0008061	chitin binding
0.35	GO:0005509	calcium ion binding
0.35	GO:0008233	peptidase activity
0.34	GO:0016301	kinase activity
0.34	GO:0008955	peptidoglycan glycosyltransferase activity
0.34	GO:0071949	FAD binding
0.34	GO:0005044	scavenger receptor activity

0.63	GO:0005581	collagen trimer
0.51	GO:0031012	extracellular matrix
0.37	GO:0005615	extracellular space
0.36	GO:0019867	outer membrane
0.35	GO:0099081	supramolecular polymer
0.35	GO:0005783	endoplasmic reticulum
0.34	GO:1903561	extracellular vesicle
0.34	GO:0030479	actin cortical patch
0.33	GO:0070013	intracellular organelle lumen
0.33	GO:0005886	plasma membrane

0.35

GO:0008233

tr|T1G0W0|T1G0W0_HELRO
Uncharacterized protein
Search

0.41	Canopy FGF signaling regulator 4

0.60	GO:0061077	chaperone-mediated protein folding
0.46	GO:1903078	positive regulation of protein localization to plasma membrane
0.40	GO:0006357	regulation of transcription by RNA polymerase II
0.39	GO:0008033	tRNA processing
0.38	GO:0032259	methylation
0.35	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.34	GO:0042981	regulation of apoptotic process

0.59	GO:0051087	chaperone binding
0.42	GO:0005102	receptor binding
0.42	GO:0001104	RNA polymerase II transcription cofactor activity
0.38	GO:0008168	methyltransferase activity
0.37	GO:0008080	N-acetyltransferase activity
0.36	GO:0046872	metal ion binding
0.35	GO:0038062	protein tyrosine kinase collagen receptor activity

0.44	GO:0044451	nucleoplasm part
0.41	GO:0034708	methyltransferase complex
0.40	GO:0012505	endomembrane system
0.39	GO:0005576	extracellular region
0.37	GO:0043234	protein complex
0.35	GO:0044444	cytoplasmic part
0.34	GO:0005887	integral component of plasma membrane

0.38

GO:0008168

tr|T1G0W1|T1G0W1_HELRO
Uncharacterized protein
Search

0.38	Collagen triple helix repeat-containing protein (Fragment)

0.42	GO:0030198	extracellular matrix organization
0.41	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.39	GO:0048731	system development
0.39	GO:0071230	cellular response to amino acid stimulus
0.39	GO:0052548	regulation of endopeptidase activity
0.38	GO:0048589	developmental growth
0.38	GO:0010466	negative regulation of peptidase activity
0.38	GO:0009653	anatomical structure morphogenesis
0.36	GO:0048468	cell development
0.36	GO:0016049	cell growth

0.55	GO:0042302	structural constituent of cuticle
0.55	GO:0005201	extracellular matrix structural constituent
0.39	GO:0004867	serine-type endopeptidase inhibitor activity
0.35	GO:0005509	calcium ion binding
0.35	GO:0005178	integrin binding
0.34	GO:0030246	carbohydrate binding
0.33	GO:0004872	receptor activity
0.32	GO:0004497	monooxygenase activity

0.61	GO:0005581	collagen trimer
0.50	GO:0044420	extracellular matrix component
0.48	GO:0005578	proteinaceous extracellular matrix
0.39	GO:0099081	supramolecular polymer
0.35	GO:0030056	hemidesmosome
0.34	GO:0005783	endoplasmic reticulum
0.30	GO:0016020	membrane

tr|T1G0W2|T1G0W2_HELRO
Uncharacterized protein
Search

SIX1

0.90	Sine oculis Homeobox like 1

0.63	GO:0008283	cell proliferation
0.62	GO:0006915	apoptotic process
0.59	GO:0048513	animal organ development
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0072107	positive regulation of ureteric bud formation
0.53	GO:0072095	regulation of branch elongation involved in ureteric bud branching
0.52	GO:0071699	olfactory placode morphogenesis
0.52	GO:0061055	myotome development

0.64	GO:0043565	sequence-specific DNA binding
0.51	GO:0003700	DNA binding transcription factor activity
0.47	GO:0001012	RNA polymerase II regulatory region DNA binding
0.46	GO:0003682	chromatin binding
0.45	GO:0003690	double-stranded DNA binding
0.39	GO:0001223	transcription coactivator binding
0.32	GO:0046872	metal ion binding

0.61	GO:0005634	nucleus
0.46	GO:0005667	transcription factor complex
0.43	GO:0070013	intracellular organelle lumen
0.40	GO:0043232	intracellular non-membrane-bounded organelle
0.39	GO:0044446	intracellular organelle part
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|T1G0W3|T1G0W3_HELRO
Uncharacterized protein
Search

0.44	TWiK family of potassium channels protein 7

0.71	GO:0071805	potassium ion transmembrane transport
0.43	GO:0030322	stabilization of membrane potential
0.35	GO:0035725	sodium ion transmembrane transport
0.33	GO:0032259	methylation

0.74	GO:0005267	potassium channel activity
0.43	GO:0022840	leak channel activity
0.35	GO:0005272	sodium channel activity
0.34	GO:0005509	calcium ion binding
0.33	GO:0008168	methyltransferase activity

0.38

GO:0005887

integral component of plasma membrane

0.33

GO:0008168

tr|T1G0W4|T1G0W4_HELRO
Uncharacterized protein
Search

0.72	Zinc finger protein Gfi-1 (Fragment)

0.61	GO:0051569	regulation of histone H3-K4 methylation
0.58	GO:0030097	hemopoiesis
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.44	GO:0016360	sensory organ precursor cell fate determination
0.44	GO:0008594	photoreceptor cell morphogenesis
0.44	GO:0008407	chaeta morphogenesis
0.43	GO:0042051	compound eye photoreceptor development
0.42	GO:0007422	peripheral nervous system development

0.51	GO:0003676	nucleic acid binding
0.43	GO:0043425	bHLH transcription factor binding
0.43	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.42	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.36	GO:0001085	RNA polymerase II transcription factor binding
0.36	GO:0008013	beta-catenin binding
0.34	GO:0003707	steroid hormone receptor activity
0.33	GO:0046872	metal ion binding

0.42	GO:0005700	polytene chromosome
0.38	GO:0005634	nucleus
0.35	GO:0005667	transcription factor complex
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

tr|T1G0W5|T1G0W5_HELRO
Uncharacterized protein
Search

FCF1

0.82	U3 small nucleolar RNA-associated protein 24

0.50	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.47	GO:0000479	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.46	GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

0.33

GO:0003723

RNA binding

0.79	GO:0032040	small-subunit processome
0.43	GO:0005730	nucleolus
0.33	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1G0W6|T1G0W6_HELRO
Uncharacterized protein
Search

0.83	Potassium voltage-gated channel protein Shal

0.78	GO:0051260	protein homooligomerization
0.77	GO:0034765	regulation of ion transmembrane transport
0.73	GO:0071805	potassium ion transmembrane transport
0.37	GO:0035637	multicellular organismal signaling
0.37	GO:0003008	system process
0.37	GO:0007610	behavior
0.36	GO:0001508	action potential
0.36	GO:0008016	regulation of heart contraction
0.36	GO:0007268	chemical synaptic transmission
0.35	GO:0099625	ventricular cardiac muscle cell membrane repolarization

0.78	GO:0005249	voltage-gated potassium channel activity
0.35	GO:0005515	protein binding
0.34	GO:0004672	protein kinase activity
0.33	GO:0046872	metal ion binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.78	GO:0008076	voltage-gated potassium channel complex
0.39	GO:0036477	somatodendritic compartment
0.39	GO:0044297	cell body
0.37	GO:0043005	neuron projection
0.37	GO:0120038	plasma membrane bounded cell projection part
0.34	GO:0045211	postsynaptic membrane

tr|T1G0W7|T1G0W7_HELRO
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12
Search

0.77	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12

0.61	GO:0022900	electron transport chain
0.40	GO:0006979	response to oxidative stress
0.37	GO:0009735	response to cytokinin
0.34	GO:0043401	steroid hormone mediated signaling pathway
0.33	GO:0016310	phosphorylation
0.33	GO:0046034	ATP metabolic process
0.33	GO:0045333	cellular respiration
0.33	GO:0036211	protein modification process
0.32	GO:0006351	transcription, DNA-templated
0.32	GO:0044267	cellular protein metabolic process

0.69	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.62	GO:0009055	electron transfer activity
0.36	GO:0050897	cobalt ion binding
0.34	GO:0003707	steroid hormone receptor activity
0.33	GO:0004672	protein kinase activity
0.33	GO:0043565	sequence-specific DNA binding
0.33	GO:0008270	zinc ion binding
0.33	GO:0003700	DNA binding transcription factor activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding

0.61	GO:0070469	respiratory chain
0.61	GO:0031966	mitochondrial membrane
0.61	GO:0019866	organelle inner membrane
0.43	GO:0030964	NADH dehydrogenase complex
0.42	GO:0098798	mitochondrial protein complex
0.41	GO:1990204	oxidoreductase complex
0.39	GO:0098796	membrane protein complex
0.33	GO:0005829	cytosol
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0008137

tr|T1G0W8|T1G0W8_HELRO
Uncharacterized protein
Search

0.80	GO:0006654	phosphatidic acid biosynthetic process
0.79	GO:0048017	inositol lipid-mediated signaling
0.67	GO:0016042	lipid catabolic process
0.37	GO:0048364	root development
0.37	GO:0016036	cellular response to phosphate starvation
0.37	GO:0019375	galactolipid biosynthetic process
0.36	GO:0006995	cellular response to nitrogen starvation
0.36	GO:0048870	cell motility
0.35	GO:0009733	response to auxin
0.35	GO:0060627	regulation of vesicle-mediated transport

0.82	GO:0004630	phospholipase D activity
0.76	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity
0.57	GO:0035091	phosphatidylinositol binding
0.32	GO:0046873	metal ion transmembrane transporter activity
0.32	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.32	GO:0005261	cation channel activity
0.32	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.32	GO:0001882	nucleoside binding
0.32	GO:0003677	DNA binding
0.32	GO:0008270	zinc ion binding

0.44	GO:0005622	intracellular
0.35	GO:0012505	endomembrane system
0.35	GO:0043227	membrane-bounded organelle
0.30	GO:0016020	membrane

0.82

EC:3.1.4.4

GO:0004630

tr|T1G0W9|T1G0W9_HELRO
Uncharacterized protein
Search

ABHD13

0.71	Abhydrolase domain-containing protein 13

0.66

GO:0002084

protein depalmitoylation

0.66

GO:0008474

palmitoyl-(protein) hydrolase activity

0.68	GO:0032839	dendrite cytoplasm
0.30	GO:0044425	membrane part

0.66

EC:3.1.2.22

GO:0008474

tr|T1G0X0|T1G0X0_HELRO
Uncharacterized protein
Search

0.25	Mediator of RNA polymerase II transcription subunit 9

0.70	GO:0006357	regulation of transcription by RNA polymerase II
0.58	GO:0006351	transcription, DNA-templated

0.79

GO:0001104

RNA polymerase II transcription cofactor activity

0.77

GO:0016592

mediator complex

tr|T1G0X1|T1G0X1_HELRO
Uncharacterized protein
Search

EGLN3

0.78	HIF prolyl hydroxylase 3

0.52	GO:0055114	oxidation-reduction process
0.46	GO:0019511	peptidyl-proline hydroxylation
0.45	GO:0001666	response to hypoxia
0.43	GO:0019471	4-hydroxyproline metabolic process
0.42	GO:0006611	protein export from nucleus
0.42	GO:0036294	cellular response to decreased oxygen levels
0.42	GO:0030307	positive regulation of cell growth
0.40	GO:0043523	regulation of neuron apoptotic process
0.39	GO:0045732	positive regulation of protein catabolic process
0.38	GO:0033554	cellular response to stress

0.78	GO:0031418	L-ascorbic acid binding
0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.62	GO:0005506	iron ion binding
0.42	GO:0019826	oxygen sensor activity
0.42	GO:0051213	dioxygenase activity
0.39	GO:0140096	catalytic activity, acting on a protein
0.35	GO:0008270	zinc ion binding
0.34	GO:0004850	uridine phosphorylase activity
0.33	GO:0003707	steroid hormone receptor activity
0.33	GO:0005509	calcium ion binding

0.42	GO:0005654	nucleoplasm
0.32	GO:0005615	extracellular space
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

tr|T1G0X2|T1G0X2_HELRO
Uncharacterized protein
Search

CAHZ

0.27	Carbonic anhydrase

0.66	GO:0006730	one-carbon metabolic process
0.43	GO:0055064	chloride ion homeostasis
0.36	GO:0015670	carbon dioxide transport
0.34	GO:0006885	regulation of pH
0.34	GO:2000878	positive regulation of oligopeptide transport
0.34	GO:2001148	regulation of dipeptide transmembrane transport
0.34	GO:2001225	regulation of chloride transport
0.34	GO:0032230	positive regulation of synaptic transmission, GABAergic
0.34	GO:0038166	angiotensin-activated signaling pathway
0.34	GO:0034764	positive regulation of transmembrane transport

0.72	GO:0004089	carbonate dehydratase activity
0.59	GO:0008270	zinc ion binding
0.34	GO:0004064	arylesterase activity

0.34	GO:0043209	myelin sheath
0.33	GO:0045177	apical part of cell
0.33	GO:0005829	cytosol
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.72

GO:0004089

tr|T1G0X3|T1G0X3_HELRO
Uncharacterized protein
Search

0.10

Ankyrin-2

0.58	GO:0007165	signal transduction
0.38	GO:0098907	regulation of SA node cell action potential
0.38	GO:0098910	regulation of atrial cardiac muscle cell action potential
0.37	GO:0086070	SA node cell to atrial cardiac muscle cell communication
0.37	GO:0086014	atrial cardiac muscle cell action potential
0.37	GO:0086005	ventricular cardiac muscle cell action potential
0.37	GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
0.37	GO:0060307	regulation of ventricular cardiac muscle cell membrane repolarization
0.37	GO:0003283	atrial septum development
0.37	GO:0086091	regulation of heart rate by cardiac conduction

0.37	GO:0030507	spectrin binding
0.37	GO:0044325	ion channel binding
0.36	GO:0019901	protein kinase binding

0.36	GO:0016323	basolateral plasma membrane
0.34	GO:0043034	costamere
0.30	GO:0031224	intrinsic component of membrane

tr|T1G0X4|T1G0X4_HELRO
Uncharacterized protein
Search

tr|T1G0X5|T1G0X5_HELRO
Uncharacterized protein
Search

tr|T1G0X6|T1G0X6_HELRO
Uncharacterized protein
Search

SAP18

0.85	Transcriptional co-repressor component

0.56	GO:0006342	chromatin silencing
0.49	GO:0048025	negative regulation of mRNA splicing, via spliceosome
0.47	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.45	GO:0043065	positive regulation of apoptotic process
0.42	GO:0008380	RNA splicing
0.41	GO:0006397	mRNA processing
0.39	GO:0006886	intracellular protein transport
0.39	GO:0016192	vesicle-mediated transport
0.38	GO:0016575	histone deacetylation
0.38	GO:0006351	transcription, DNA-templated

0.56	GO:0003714	transcription corepressor activity
0.52	GO:0008134	transcription factor binding
0.38	GO:0004407	histone deacetylase activity
0.38	GO:0003723	RNA binding
0.38	GO:0004565	beta-galactosidase activity

0.70	GO:0016604	nuclear body
0.62	GO:0005829	cytosol
0.50	GO:0061574	ASAP complex
0.45	GO:0035145	exon-exon junction complex
0.42	GO:0030123	AP-3 adaptor complex
0.42	GO:0000118	histone deacetylase complex
0.37	GO:0005667	transcription factor complex

0.38

EC:3.5.1.98

GO:0004407

tr|T1G0X7|T1G0X7_HELRO
Uncharacterized protein
Search

0.73	GO:0016567	protein ubiquitination
0.39	GO:0010994	free ubiquitin chain polymerization
0.39	GO:0051974	negative regulation of telomerase activity
0.37	GO:0010091	trichome branching
0.36	GO:0042023	DNA endoreduplication
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:0010468	regulation of gene expression
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:0010467	gene expression

0.74	GO:0004842	ubiquitin-protein transferase activity
0.49	GO:0016874	ligase activity
0.42	GO:0061659	ubiquitin-like protein ligase activity
0.36	GO:0008270	zinc ion binding
0.34	GO:0046982	protein heterodimerization activity
0.33	GO:0043565	sequence-specific DNA binding
0.32	GO:0003735	structural constituent of ribosome

0.36	GO:0005737	cytoplasm
0.33	GO:0005886	plasma membrane
0.33	GO:1905369	endopeptidase complex
0.33	GO:0005634	nucleus
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.32	GO:0043234	protein complex
0.32	GO:0043232	intracellular non-membrane-bounded organelle
0.32	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.49	EC:6	GO:0016874
0.74	KEGG:R03876	GO:0004842

tr|T1G0X8|T1G0X8_HELRO
Uncharacterized protein
Search

DDX47

0.47	DEAD box ATP-dependent RNA helicase

0.53	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors
0.47	GO:0008380	RNA splicing
0.47	GO:0006364	rRNA processing
0.46	GO:0010501	RNA secondary structure unwinding
0.35	GO:0006397	mRNA processing
0.33	GO:0006508	proteolysis
0.33	GO:0043632	modification-dependent macromolecule catabolic process
0.33	GO:0044257	cellular protein catabolic process
0.33	GO:0035556	intracellular signal transduction

0.67	GO:0004386	helicase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0003676	nucleic acid binding
0.45	GO:0008186	RNA-dependent ATPase activity
0.40	GO:0140098	catalytic activity, acting on RNA
0.33	GO:0004222	metalloendopeptidase activity
0.33	GO:0005515	protein binding
0.32	GO:0046872	metal ion binding

0.49	GO:0005730	nucleolus
0.36	GO:0005737	cytoplasm
0.33	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

0.33

GO:0004222

tr|T1G0X9|T1G0X9_HELRO
Uncharacterized protein
Search

tr|T1G0Y0|T1G0Y0_HELRO
Uncharacterized protein
Search

0.38	Exosporium leader peptide

0.42	GO:0032836	glomerular basement membrane development
0.37	GO:0051276	chromosome organization
0.36	GO:0035890	exit from host
0.35	GO:0019058	viral life cycle
0.35	GO:0005975	carbohydrate metabolic process
0.34	GO:0009057	macromolecule catabolic process
0.34	GO:0006355	regulation of transcription, DNA-templated
0.33	GO:0007155	cell adhesion
0.32	GO:0006351	transcription, DNA-templated

0.68	GO:0005201	extracellular matrix structural constituent
0.39	GO:0030246	carbohydrate binding
0.39	GO:0005509	calcium ion binding
0.36	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.35	GO:0042393	histone binding
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0004386	helicase activity
0.33	GO:0016887	ATPase activity

0.69	GO:0005581	collagen trimer
0.67	GO:0005604	basement membrane
0.42	GO:0098645	collagen network
0.38	GO:0098025	virus tail, baseplate
0.37	GO:0005694	chromosome
0.34	GO:0031981	nuclear lumen
0.34	GO:1904949	ATPase complex
0.30	GO:0016020	membrane

0.36

GO:0004553

tr|T1G0Y1|T1G0Y1_HELRO
Uncharacterized protein
Search

0.78	Mitochondrial ribosomal protein L45

0.36

GO:0032543

mitochondrial translation

0.34

GO:0003735

structural constituent of ribosome

0.57	GO:0005840	ribosome
0.46	GO:0005739	mitochondrion
0.36	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part
0.34	GO:0031090	organelle membrane
0.33	GO:0031975	envelope

tr|T1G0Y2|T1G0Y2_HELRO
Uncharacterized protein
Search

PRKAR1A

0.71	cAMP-dependent protein kinase type I-alpha regulatory subunit

0.75	GO:0045859	regulation of protein kinase activity
0.51	GO:0016310	phosphorylation
0.50	GO:0046007	negative regulation of activated T cell proliferation
0.48	GO:0060038	cardiac muscle cell proliferation
0.47	GO:0045214	sarcomere organization
0.47	GO:0001707	mesoderm formation
0.47	GO:0033673	negative regulation of kinase activity
0.45	GO:0001933	negative regulation of protein phosphorylation
0.36	GO:0051445	regulation of meiotic cell cycle
0.35	GO:0010564	regulation of cell cycle process

0.84	GO:0008603	cAMP-dependent protein kinase regulator activity
0.82	GO:0030552	cAMP binding
0.53	GO:0016301	kinase activity
0.49	GO:0034236	protein kinase A catalytic subunit binding
0.49	GO:0004862	cAMP-dependent protein kinase inhibitor activity
0.46	GO:0031625	ubiquitin protein ligase binding
0.45	GO:0019904	protein domain specific binding
0.34	GO:0042802	identical protein binding

0.83	GO:0005952	cAMP-dependent protein kinase complex
0.49	GO:0001772	immunological synapse
0.48	GO:0031588	nucleotide-activated protein kinase complex
0.47	GO:0044853	plasma membrane raft
0.47	GO:0031594	neuromuscular junction
0.47	GO:0005930	axoneme
0.30	GO:0016021	integral component of membrane

tr|T1G0Y3|T1G0Y3_HELRO
Uncharacterized protein
Search

KAZN

0.64	Kazrin, periplakin interacting protein (Fragment)

0.57	GO:0050808	synapse organization
0.50	GO:0031424	keratinization
0.41	GO:0012501	programmed cell death
0.37	GO:0090128	regulation of synapse maturation
0.36	GO:0045664	regulation of neuron differentiation
0.34	GO:2001141	regulation of RNA biosynthetic process
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.39

GO:0005515

protein binding

0.77	GO:0001533	cornified envelope
0.76	GO:0030057	desmosome
0.71	GO:0016607	nuclear speck
0.61	GO:0005829	cytosol
0.48	GO:0045202	synapse
0.43	GO:0005856	cytoskeleton

tr|T1G0Y4|T1G0Y4_HELRO
Uncharacterized protein
Search

GCNT1

0.69	Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase

0.59	GO:0060352	cell adhesion molecule production
0.57	GO:0050901	leukocyte tethering or rolling
0.55	GO:0060993	kidney morphogenesis
0.52	GO:0048729	tissue morphogenesis
0.50	GO:0009101	glycoprotein biosynthetic process
0.38	GO:0043413	macromolecule glycosylation
0.37	GO:0032868	response to insulin
0.37	GO:0002426	immunoglobulin production in mucosal tissue
0.37	GO:0002121	inter-male aggressive behavior
0.36	GO:0050892	intestinal absorption

0.77	GO:0008375	acetylglucosaminyltransferase activity
0.43	GO:0140103	catalytic activity, acting on a glycoprotein
0.35	GO:0008878	glucose-1-phosphate adenylyltransferase activity
0.33	GO:0030414	peptidase inhibitor activity
0.33	GO:0005515	protein binding

0.52	GO:0031985	Golgi cisterna
0.52	GO:0005802	trans-Golgi network
0.37	GO:0000139	Golgi membrane
0.36	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane

0.77	EC:2.4.1	GO:0008375
0.35	KEGG:R00948	GO:0008878

tr|T1G0Y5|T1G0Y5_HELRO
Uncharacterized protein
Search

0.55

GO:0055085

transmembrane transport

0.57

GO:0022857

transmembrane transporter activity

0.30

GO:0044425

membrane part

tr|T1G0Y6|T1G0Y6_HELRO
Uncharacterized protein
Search

0.66	GO:0030001	metal ion transport
0.55	GO:0055085	transmembrane transport
0.41	GO:0072511	divalent inorganic cation transport
0.35	GO:0034224	cellular response to zinc ion starvation
0.34	GO:0048026	positive regulation of mRNA splicing, via spliceosome
0.34	GO:0006414	translational elongation
0.34	GO:0030509	BMP signaling pathway
0.34	GO:0001654	eye development
0.33	GO:0032259	methylation

0.69	GO:0046873	metal ion transmembrane transporter activity
0.42	GO:0072509	divalent inorganic cation transmembrane transporter activity
0.34	GO:0003746	translation elongation factor activity
0.34	GO:0003924	GTPase activity
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0019001	guanyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0008168	methyltransferase activity
0.33	GO:0030554	adenyl nucleotide binding

0.36	GO:0005886	plasma membrane
0.32	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.33

GO:0008168

tr|T1G0Y7|T1G0Y7_HELRO
Uncharacterized protein
Search

0.59	6-pyruvoyl tetrahydrobiopterin synthase

0.79	GO:0046146	tetrahydrobiopterin metabolic process
0.79	GO:0034312	diol biosynthetic process
0.72	GO:0042559	pteridine-containing compound biosynthetic process
0.64	GO:0009108	coenzyme biosynthetic process
0.47	GO:0019889	pteridine metabolic process
0.41	GO:0046148	pigment biosynthetic process
0.34	GO:0046655	folic acid metabolic process
0.34	GO:0006437	tyrosyl-tRNA aminoacylation
0.33	GO:0006979	response to oxidative stress
0.33	GO:0042398	cellular modified amino acid biosynthetic process

0.85	GO:0003874	6-pyruvoyltetrahydropterin synthase activity
0.43	GO:0046872	metal ion binding
0.38	GO:0042802	identical protein binding
0.35	GO:0046983	protein dimerization activity
0.34	GO:0004831	tyrosine-tRNA ligase activity
0.33	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.33	GO:0003677	DNA binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.34	GO:0005739	mitochondrion
0.32	GO:0005921	gap junction
0.31	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.85	EC:4.2.3.12	GO:0003874
0.85	KEGG:R04286	GO:0003874

tr|T1G0Y8|T1G0Y8_HELRO
Uncharacterized protein
Search

LRRC49

0.94	Tubulin polyglutamylase complex subunit 4

0.53	GO:0018095	protein polyglutamylation
0.39	GO:0060271	cilium assembly
0.39	GO:0071727	cellular response to triacyl bacterial lipopeptide
0.39	GO:0034137	positive regulation of toll-like receptor 2 signaling pathway
0.39	GO:0034130	toll-like receptor 1 signaling pathway
0.39	GO:0042495	detection of triacyl bacterial lipopeptide
0.39	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process
0.39	GO:2000484	positive regulation of interleukin-8 secretion
0.39	GO:0045410	positive regulation of interleukin-6 biosynthetic process
0.39	GO:0022008	neurogenesis

0.39	GO:0035663	Toll-like receptor 2 binding
0.39	GO:0071723	lipopeptide binding
0.38	GO:0003777	microtubule motor activity
0.38	GO:0008017	microtubule binding
0.38	GO:0005044	scavenger receptor activity
0.38	GO:0004613	phosphoenolpyruvate carboxykinase (GTP) activity
0.37	GO:0016301	kinase activity
0.36	GO:0046982	protein heterodimerization activity
0.36	GO:0004888	transmembrane signaling receptor activity
0.36	GO:0016887	ATPase activity

0.54	GO:0005874	microtubule
0.45	GO:0005829	cytosol
0.40	GO:0005871	kinesin complex
0.39	GO:0035354	Toll-like receptor 1-Toll-like receptor 2 protein complex
0.37	GO:0045121	membrane raft
0.36	GO:0005794	Golgi apparatus
0.35	GO:0005887	integral component of plasma membrane

0.38

EC:4.1.1.32

GO:0004613

tr|T1G0Y9|T1G0Y9_HELRO
Uncharacterized protein
Search

0.83	Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B

0.60	GO:0005975	carbohydrate metabolic process
0.34	GO:0006457	protein folding
0.34	GO:0060051	negative regulation of protein glycosylation

0.69	GO:0016758	transferase activity, transferring hexosyl groups
0.34	GO:0051082	unfolded protein binding
0.34	GO:0005509	calcium ion binding

0.35	GO:0005783	endoplasmic reticulum
0.33	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.33	GO:0005795	Golgi stack
0.30	GO:0044425	membrane part

0.69

GO:0016758

tr|T1G0Z0|T1G0Z0_HELRO
Uncharacterized protein
Search

DSTYK

0.94	Dual serine/threonine and tyrosine protein kinase

0.62	GO:0006468	protein phosphorylation
0.55	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway
0.52	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.52	GO:0044344	cellular response to fibroblast growth factor stimulus
0.50	GO:0033674	positive regulation of kinase activity
0.50	GO:0043066	negative regulation of apoptotic process
0.42	GO:0048568	embryonic organ development
0.42	GO:0018212	peptidyl-tyrosine modification
0.39	GO:0035556	intracellular signal transduction

0.62	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding

0.54	GO:0016323	basolateral plasma membrane
0.53	GO:0016324	apical plasma membrane
0.42	GO:0030054	cell junction
0.41	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

tr|T1G0Z1|T1G0Z1_HELRO
DNA-directed RNA polymerase subunit beta
Search

POLR2B

0.41	DNA-directed RNA polymerase subunit beta

0.58	GO:0006351	transcription, DNA-templated
0.35	GO:0035019	somatic stem cell population maintenance
0.35	GO:0060964	regulation of gene silencing by miRNA
0.34	GO:0008543	fibroblast growth factor receptor signaling pathway
0.34	GO:0016073	snRNA metabolic process
0.34	GO:0050434	positive regulation of viral transcription
0.34	GO:0006283	transcription-coupled nucleotide-excision repair
0.34	GO:0000398	mRNA splicing, via spliceosome
0.34	GO:0006370	7-methylguanosine mRNA capping

0.70	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.65	GO:0001882	nucleoside binding
0.55	GO:0003677	DNA binding
0.49	GO:0003682	chromatin binding
0.34	GO:0005515	protein binding
0.33	GO:0003723	RNA binding
0.33	GO:0046872	metal ion binding

0.53	GO:0005665	DNA-directed RNA polymerase II, core complex
0.52	GO:0000784	nuclear chromosome, telomeric region
0.30	GO:0031224	intrinsic component of membrane

0.70

GO:0003899

tr|T1G0Z2|T1G0Z2_HELRO
Uncharacterized protein
Search

EOGT

0.38	EGF domain-specific O-linked N-acetylglucosamine transferase

0.48	GO:0097370	protein O-GlcNAcylation via threonine
0.47	GO:0008363	larval chitin-based cuticle development
0.37	GO:0022900	electron transport chain
0.36	GO:0043461	proton-transporting ATP synthase complex assembly

0.65	GO:0016757	transferase activity, transferring glycosyl groups
0.40	GO:0140096	catalytic activity, acting on a protein
0.39	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.38	GO:0009055	electron transfer activity

0.45	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0031224	intrinsic component of membrane

0.65

GO:0016757

tr|T1G0Z3|T1G0Z3_HELRO
Uncharacterized protein
Search

0.69	Vacuolar protein sorting-associated protein 13C (Fragment)

0.79	GO:1905090	negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
0.63	GO:0007005	mitochondrion organization
0.51	GO:0035176	social behavior
0.49	GO:0007626	locomotory behavior
0.47	GO:0006914	autophagy
0.46	GO:0007399	nervous system development

0.65	GO:0005741	mitochondrial outer membrane
0.58	GO:0005829	cytosol
0.52	GO:0031045	dense core granule
0.42	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

tr|T1G0Z4|T1G0Z4_HELRO
Uncharacterized protein
Search

0.31	Flagellar hook-length control protein FliK

0.41	GO:0010466	negative regulation of peptidase activity
0.41	GO:0052548	regulation of endopeptidase activity
0.40	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.39	GO:0071230	cellular response to amino acid stimulus
0.38	GO:0030198	extracellular matrix organization
0.37	GO:0035987	endodermal cell differentiation
0.35	GO:0050673	epithelial cell proliferation
0.35	GO:0010811	positive regulation of cell-substrate adhesion
0.35	GO:0048593	camera-type eye morphogenesis
0.35	GO:0007155	cell adhesion

0.66	GO:0005201	extracellular matrix structural constituent
0.41	GO:0030414	peptidase inhibitor activity
0.41	GO:0061135	endopeptidase regulator activity
0.40	GO:0042302	structural constituent of cuticle
0.36	GO:0030246	carbohydrate binding
0.35	GO:0005509	calcium ion binding
0.34	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.34	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.34	GO:0004674	protein serine/threonine kinase activity
0.34	GO:0005044	scavenger receptor activity

0.62	GO:0005581	collagen trimer
0.54	GO:0005604	basement membrane
0.40	GO:0098645	collagen network
0.34	GO:0005615	extracellular space
0.34	GO:0019867	outer membrane
0.30	GO:0016021	integral component of membrane

0.34

GO:0003755

tr|T1G0Z5|T1G0Z5_HELRO
Uncharacterized protein
Search

0.54	GO:0042448	progesterone metabolic process
0.53	GO:0055114	oxidation-reduction process
0.51	GO:0006704	glucocorticoid biosynthetic process
0.38	GO:2000863	positive regulation of estrogen secretion
0.38	GO:0001998	angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure
0.37	GO:0097254	renal tubular secretion
0.37	GO:0006702	androgen biosynthetic process
0.36	GO:0044550	secondary metabolite biosynthetic process
0.35	GO:0007548	sex differentiation
0.35	GO:0016125	sterol metabolic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.66	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.54	GO:0047442	17-alpha-hydroxyprogesterone aldolase activity
0.35	GO:0019825	oxygen binding
0.35	GO:0005496	steroid binding
0.32	GO:0016798	hydrolase activity, acting on glycosyl bonds

0.47	GO:0043025	neuronal cell body
0.47	GO:0030424	axon
0.40	GO:0005739	mitochondrion
0.38	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

0.68

GO:0016705

tr|T1G0Z6|T1G0Z6_HELRO
Uncharacterized protein
Search

0.83	Mitochondrial ribosomal protein L43

0.36

GO:0032543

mitochondrial translation

0.42	GO:0003735	structural constituent of ribosome
0.36	GO:0003860	3-hydroxyisobutyryl-CoA hydrolase activity

0.61	GO:0005840	ribosome
0.46	GO:0005759	mitochondrial matrix

0.36

EC:3.1.2.4

GO:0003860

tr|T1G0Z7|T1G0Z7_HELRO
Uncharacterized protein
Search

0.31	Heterogeneous nuclear ribonucleoprotein A1 (inferred by orthology to a C. elegans protein)

0.42	GO:0001745	compound eye morphogenesis
0.42	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.41	GO:0003006	developmental process involved in reproduction
0.41	GO:0061458	reproductive system development
0.39	GO:0042594	response to starvation
0.39	GO:0009408	response to heat
0.37	GO:2000070	regulation of response to water deprivation
0.36	GO:1901000	regulation of response to salt stress
0.36	GO:0036099	female germ-line stem cell population maintenance
0.35	GO:0033119	negative regulation of RNA splicing

0.59	GO:0003723	RNA binding
0.38	GO:0043565	sequence-specific DNA binding
0.33	GO:0003777	microtubule motor activity
0.33	GO:0008017	microtubule binding
0.33	GO:0008270	zinc ion binding
0.32	GO:0031625	ubiquitin protein ligase binding
0.32	GO:0005272	sodium channel activity
0.32	GO:0017076	purine nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.54	GO:0019013	viral nucleocapsid
0.49	GO:0030529	intracellular ribonucleoprotein complex
0.43	GO:0005703	polytene chromosome puff
0.42	GO:0035062	omega speckle
0.40	GO:0000792	heterochromatin
0.34	GO:0005829	cytosol
0.32	GO:0000151	ubiquitin ligase complex
0.30	GO:0016020	membrane

0.32	EC:2.7.1.11	GO:0003872
0.32	KEGG:R03876	GO:0004842

tr|T1G0Z8|T1G0Z8_HELRO
Uncharacterized protein
Search

RSU1

0.93	Ras suppressor protein 1

0.83	GO:0010811	positive regulation of cell-substrate adhesion
0.74	GO:0043547	positive regulation of GTPase activity
0.45	GO:2000179	positive regulation of neural precursor cell proliferation
0.44	GO:0007265	Ras protein signal transduction
0.39	GO:0042953	lipoprotein transport
0.38	GO:0006898	receptor-mediated endocytosis

0.39	GO:0005515	protein binding
0.36	GO:0005509	calcium ion binding

0.80	GO:0005925	focal adhesion
0.46	GO:0070062	extracellular exosome
0.40	GO:0005903	brush border
0.40	GO:0016324	apical plasma membrane
0.40	GO:0030139	endocytic vesicle
0.40	GO:0005905	clathrin-coated pit
0.39	GO:0005768	endosome
0.38	GO:0005794	Golgi apparatus
0.38	GO:0005783	endoplasmic reticulum
0.37	GO:0005829	cytosol

tr|T1G0Z9|T1G0Z9_HELRO
Uncharacterized protein
Search

0.53	GO:0055114	oxidation-reduction process
0.45	GO:0006697	ecdysone biosynthetic process
0.44	GO:0008362	chitin-based embryonic cuticle biosynthetic process
0.44	GO:0008258	head involution
0.44	GO:0007494	midgut development
0.44	GO:0007391	dorsal closure
0.41	GO:0007417	central nervous system development
0.37	GO:0019373	epoxygenase P450 pathway
0.36	GO:0051501	diterpene phytoalexin metabolic process
0.36	GO:0052315	phytoalexin biosynthetic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.65	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.34	GO:0019825	oxygen binding
0.32	GO:0016787	hydrolase activity
0.32	GO:0009055	electron transfer activity

0.37	GO:0005739	mitochondrion
0.34	GO:0071203	WASH complex
0.32	GO:0031967	organelle envelope
0.32	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

0.68

GO:0016705

tr|T1G100|T1G100_HELRO
Uncharacterized protein
Search

tr|T1G101|T1G101_HELRO
Uncharacterized protein
Search

tr|T1G102|T1G102_HELRO
Uncharacterized protein
Search

WDR13

0.96	WD repeat-containing protein 13

0.85	GO:1904691	negative regulation of type B pancreatic cell proliferation
0.36	GO:0006886	intracellular protein transport

0.79

GO:1990841

promoter-specific chromatin binding

0.70	GO:0005815	microtubule organizing center
0.65	GO:0005654	nucleoplasm
0.52	GO:0005886	plasma membrane
0.36	GO:0005783	endoplasmic reticulum
0.30	GO:0031224	intrinsic component of membrane

tr|T1G103|T1G103_HELRO
Uncharacterized protein
Search

0.10	Collagen-like triple helix repeat-containing protein (Fragment)

0.39	GO:0007155	cell adhesion
0.37	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.36	GO:0007528	neuromuscular junction development
0.35	GO:0035848	oviduct morphogenesis
0.35	GO:0048546	digestive tract morphogenesis
0.35	GO:0014706	striated muscle tissue development
0.35	GO:0060729	intestinal epithelial structure maintenance
0.35	GO:0015074	DNA integration
0.35	GO:0061061	muscle structure development
0.34	GO:0048468	cell development

0.67	GO:0005201	extracellular matrix structural constituent
0.43	GO:0042302	structural constituent of cuticle
0.35	GO:0005509	calcium ion binding
0.33	GO:0030246	carbohydrate binding
0.33	GO:0003677	DNA binding
0.33	GO:0042803	protein homodimerization activity
0.32	GO:0004252	serine-type endopeptidase activity
0.32	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.72	GO:0005581	collagen trimer
0.65	GO:0005604	basement membrane
0.38	GO:0098645	collagen network
0.36	GO:0031594	neuromuscular junction
0.36	GO:0005615	extracellular space
0.30	GO:0016020	membrane

0.32

GO:0004252

tr|T1G104|T1G104_HELRO
Uncharacterized protein
Search

0.10	collagen alpha-2(V) chain-like

0.38	GO:0071230	cellular response to amino acid stimulus
0.37	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.37	GO:0030198	extracellular matrix organization
0.37	GO:0007275	multicellular organism development
0.36	GO:0009653	anatomical structure morphogenesis
0.36	GO:0007155	cell adhesion
0.36	GO:0033622	integrin activation
0.36	GO:0051894	positive regulation of focal adhesion assembly
0.35	GO:0051093	negative regulation of developmental process
0.35	GO:0051241	negative regulation of multicellular organismal process

0.64	GO:0005201	extracellular matrix structural constituent
0.50	GO:0042302	structural constituent of cuticle
0.35	GO:0005178	integrin binding
0.35	GO:0043394	proteoglycan binding
0.35	GO:1901681	sulfur compound binding
0.34	GO:0005509	calcium ion binding
0.34	GO:0046332	SMAD binding
0.34	GO:0005539	glycosaminoglycan binding
0.34	GO:0004867	serine-type endopeptidase inhibitor activity
0.34	GO:0033293	monocarboxylic acid binding

0.63	GO:0005581	collagen trimer
0.55	GO:0044420	extracellular matrix component
0.52	GO:0005578	proteinaceous extracellular matrix
0.38	GO:0099081	supramolecular polymer
0.36	GO:0005615	extracellular space
0.34	GO:1903561	extracellular vesicle
0.34	GO:0031594	neuromuscular junction
0.31	GO:0005622	intracellular
0.30	GO:0016020	membrane

0.32

GO:0016740

tr|T1G105|T1G105_HELRO
Uncharacterized protein
Search

LOC106175285

0.79	Intermediate filament gliarin

0.35	GO:0007010	cytoskeleton organization
0.34	GO:0006260	DNA replication
0.34	GO:0006310	DNA recombination
0.33	GO:0006281	DNA repair
0.33	GO:0060255	regulation of macromolecule metabolic process
0.33	GO:0080090	regulation of primary metabolic process
0.33	GO:0031323	regulation of cellular metabolic process
0.33	GO:0051171	regulation of nitrogen compound metabolic process
0.33	GO:0051346	negative regulation of hydrolase activity
0.33	GO:0009889	regulation of biosynthetic process

0.60	GO:0005198	structural molecule activity
0.36	GO:0003676	nucleic acid binding
0.35	GO:0004386	helicase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0008270	zinc ion binding
0.33	GO:0030414	peptidase inhibitor activity
0.33	GO:0008237	metallopeptidase activity

0.77	GO:0005882	intermediate filament
0.33	GO:0005576	extracellular region
0.30	GO:0016020	membrane

tr|T1G106|T1G106_HELRO
Uncharacterized protein
Search

0.71	Prohormone and neuropeptide processing protease

0.61	GO:0006508	proteolysis
0.48	GO:0035180	larval wandering behavior
0.48	GO:0035187	hatching behavior
0.44	GO:0002165	instar larval or pupal development
0.44	GO:0033500	carbohydrate homeostasis
0.42	GO:0042445	hormone metabolic process
0.42	GO:0051604	protein maturation
0.38	GO:0006518	peptide metabolic process
0.37	GO:0051216	cartilage development
0.35	GO:0010466	negative regulation of peptidase activity

0.69	GO:0004252	serine-type endopeptidase activity
0.40	GO:0005509	calcium ion binding
0.35	GO:0030414	peptidase inhibitor activity
0.33	GO:0004222	metalloendopeptidase activity
0.32	GO:0016758	transferase activity, transferring hexosyl groups

0.40	GO:0005576	extracellular region
0.34	GO:0005802	trans-Golgi network
0.32	GO:0005783	endoplasmic reticulum
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0004252

tr|T1G107|T1G107_HELRO
Uncharacterized protein
Search

tr|T1G108|T1G108_HELRO
Uncharacterized protein
Search

0.54	GO:0035176	social behavior
0.52	GO:0007626	locomotory behavior
0.50	GO:0006914	autophagy
0.49	GO:0007399	nervous system development
0.48	GO:0019538	protein metabolic process
0.42	GO:0006623	protein targeting to vacuole

0.40

GO:0005509

calcium ion binding

0.70	GO:0031902	late endosome membrane
0.55	GO:0031045	dense core granule
0.30	GO:0016021	integral component of membrane

tr|T1G109|T1G109_HELRO
Uncharacterized protein
Search

RPL35A

0.77	Ribosomal protein rpl35a

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.34	GO:0042273	ribosomal large subunit biogenesis

0.64	GO:0003735	structural constituent of ribosome
0.34	GO:0046872	metal ion binding

0.61	GO:0005840	ribosome
0.33	GO:0044445	cytosolic part
0.32	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

tr|T1G110|T1G110_HELRO
Uncharacterized protein
Search

0.72	N-acetyllactosaminide 3-alpha-galactosyltransferase

0.60	GO:0005975	carbohydrate metabolic process
0.37	GO:0045747	positive regulation of Notch signaling pathway
0.36	GO:0043413	macromolecule glycosylation
0.36	GO:0009101	glycoprotein biosynthetic process
0.35	GO:0009636	response to toxic substance
0.34	GO:0006464	cellular protein modification process

0.65	GO:0016757	transferase activity, transferring glycosyl groups
0.33	GO:0046872	metal ion binding
0.32	GO:0003723	RNA binding

0.30

GO:0044425

membrane part

0.65

GO:0016757

tr|T1G111|T1G111_HELRO
Uncharacterized protein
Search

0.44	GO:0030198	extracellular matrix organization
0.42	GO:0048731	system development
0.40	GO:0009653	anatomical structure morphogenesis
0.40	GO:0052547	regulation of peptidase activity
0.39	GO:0061448	connective tissue development
0.39	GO:0007605	sensory perception of sound
0.39	GO:0045861	negative regulation of proteolysis
0.39	GO:0051346	negative regulation of hydrolase activity
0.39	GO:0097435	supramolecular fiber organization
0.39	GO:0001894	tissue homeostasis

0.69	GO:0005201	extracellular matrix structural constituent
0.39	GO:0030414	peptidase inhibitor activity
0.38	GO:0061135	endopeptidase regulator activity
0.37	GO:0048407	platelet-derived growth factor binding
0.36	GO:0046332	SMAD binding
0.36	GO:0002020	protease binding
0.36	GO:0005178	integrin binding
0.36	GO:0005509	calcium ion binding
0.36	GO:0030674	protein binding, bridging
0.35	GO:0042802	identical protein binding

0.66	GO:0005581	collagen trimer
0.61	GO:0044420	extracellular matrix component
0.58	GO:0005578	proteinaceous extracellular matrix
0.38	GO:0099081	supramolecular polymer
0.37	GO:0005783	endoplasmic reticulum
0.36	GO:0005615	extracellular space
0.33	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.33

EC:2.7.7.49

GO:0003964

tr|T1G112|T1G112_HELRO
Uncharacterized protein
Search

0.52	GO:0031581	hemidesmosome assembly
0.50	GO:0048644	muscle organ morphogenesis
0.49	GO:0008543	fibroblast growth factor receptor signaling pathway
0.49	GO:0009792	embryo development ending in birth or egg hatching
0.48	GO:0040017	positive regulation of locomotion
0.47	GO:0016477	cell migration
0.44	GO:1905905	pharyngeal gland morphogenesis
0.43	GO:0060279	positive regulation of ovulation
0.43	GO:0060465	pharynx development
0.42	GO:0002119	nematode larval development

0.66	GO:0005509	calcium ion binding
0.41	GO:0005198	structural molecule activity
0.41	GO:0004252	serine-type endopeptidase activity
0.36	GO:0005041	low-density lipoprotein receptor activity
0.36	GO:0050750	low-density lipoprotein particle receptor binding
0.33	GO:0016874	ligase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.49	GO:0005604	basement membrane
0.43	GO:0055120	striated muscle dense body
0.42	GO:0043235	receptor complex
0.37	GO:0005794	Golgi apparatus
0.36	GO:0031430	M band
0.35	GO:0019897	extrinsic component of plasma membrane
0.30	GO:0016021	integral component of membrane

0.41

GO:0004252

tr|T1G113|T1G113_HELRO
Uncharacterized protein
Search

0.72	GO:0016560	protein import into peroxisome matrix, docking
0.39	GO:0007218	neuropeptide signaling pathway

0.65	GO:0030674	protein binding, bridging
0.44	GO:0030246	carbohydrate binding

0.69	GO:1990429	peroxisomal importomer complex
0.66	GO:0005777	peroxisome
0.64	GO:0031903	microbody membrane
0.44	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

tr|T1G114|T1G114_HELRO
Uncharacterized protein
Search

0.60

GO:0007165

signal transduction

0.30

GO:0044425

membrane part

tr|T1G115|T1G115_HELRO
Uncharacterized protein
Search

0.46	GO:0071711	basement membrane organization
0.46	GO:0048846	axon extension involved in axon guidance
0.44	GO:0007412	axon target recognition
0.44	GO:0031290	retinal ganglion cell axon guidance
0.43	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.40	GO:0071495	cellular response to endogenous stimulus
0.40	GO:0071310	cellular response to organic substance
0.39	GO:0009888	tissue development
0.39	GO:0043200	response to amino acid
0.39	GO:0016525	negative regulation of angiogenesis

0.64	GO:0005201	extracellular matrix structural constituent
0.44	GO:0042302	structural constituent of cuticle
0.38	GO:0005509	calcium ion binding
0.37	GO:0048407	platelet-derived growth factor binding
0.37	GO:0005178	integrin binding
0.34	GO:0004867	serine-type endopeptidase inhibitor activity
0.34	GO:0030246	carbohydrate binding
0.34	GO:0004674	protein serine/threonine kinase activity
0.33	GO:0004029	aldehyde dehydrogenase (NAD) activity
0.33	GO:0008641	ubiquitin-like modifier activating enzyme activity

0.68	GO:0005581	collagen trimer
0.60	GO:0005604	basement membrane
0.43	GO:0098645	collagen network
0.39	GO:0005829	cytosol
0.38	GO:0005615	extracellular space
0.35	GO:0005783	endoplasmic reticulum
0.33	GO:0070013	intracellular organelle lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.34

GO:0004674

tr|T1G116|T1G116_HELRO
Uncharacterized protein
Search

0.41	GO:0009405	pathogenesis
0.35	GO:0005975	carbohydrate metabolic process

0.73	GO:0005201	extracellular matrix structural constituent
0.36	GO:0030246	carbohydrate binding
0.36	GO:0005509	calcium ion binding
0.36	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.35	GO:0042302	structural constituent of cuticle
0.32	GO:0003676	nucleic acid binding

0.63	GO:0005581	collagen trimer
0.41	GO:0005604	basement membrane
0.40	GO:0019867	outer membrane
0.30	GO:0031224	intrinsic component of membrane

0.36

GO:0004553

tr|T1G117|T1G117_HELRO
Uncharacterized protein
Search

ECE2

0.66	Endothelin-converting enzyme

0.59	GO:0032259	methylation
0.51	GO:0016486	peptide hormone processing
0.35	GO:0010002	cardioblast differentiation
0.35	GO:0006266	DNA ligation
0.35	GO:0018205	peptidyl-lysine modification
0.35	GO:0008213	protein alkylation
0.34	GO:0007420	brain development
0.34	GO:0007267	cell-cell signaling
0.34	GO:0006310	DNA recombination
0.34	GO:0006281	DNA repair

0.60	GO:0008168	methyltransferase activity
0.45	GO:0004222	metalloendopeptidase activity
0.35	GO:0003910	DNA ligase (ATP) activity
0.33	GO:0005515	protein binding
0.33	GO:0003723	RNA binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0046872	metal ion binding

0.44	GO:0030659	cytoplasmic vesicle membrane
0.34	GO:0030133	transport vesicle
0.34	GO:0000139	Golgi membrane
0.34	GO:0098805	whole membrane
0.30	GO:0016021	integral component of membrane

0.60

GO:0008168

tr|T1G118|T1G118_HELRO
Fatty acyl-CoA reductase
Search

0.49	Fatty acyl-CoA reductase

0.62	GO:0006629	lipid metabolic process
0.52	GO:0055114	oxidation-reduction process
0.48	GO:0035336	long-chain fatty-acyl-CoA metabolic process
0.44	GO:0010025	wax biosynthetic process
0.37	GO:0008340	determination of adult lifespan
0.34	GO:1902358	sulfate transmembrane transport
0.32	GO:0006508	proteolysis
0.32	GO:0072330	monocarboxylic acid biosynthetic process

0.83	GO:0102965	alcohol-forming fatty acyl-CoA reductase activity
0.83	GO:0080019	fatty-acyl-CoA reductase (alcohol-forming) activity
0.35	GO:0008271	secondary active sulfate transmembrane transporter activity
0.34	GO:0016805	dipeptidase activity
0.33	GO:0008237	metallopeptidase activity
0.32	GO:0102756	very-long-chain 3-ketoacyl-CoA synthase activity
0.32	GO:0102338	3-oxo-lignoceronyl-CoA synthase activity
0.32	GO:0102336	3-oxo-arachidoyl-CoA synthase activity
0.32	GO:0102337	3-oxo-cerotoyl-CoA synthase activity
0.32	GO:0016887	ATPase activity

0.45	GO:0005779	integral component of peroxisomal membrane
0.33	GO:0043190	ATP-binding cassette (ABC) transporter complex

0.34

EC:3.4.13

GO:0016805

tr|T1G119|T1G119_HELRO
Uncharacterized protein
Search

0.49

Flotillin

0.51	GO:0006629	lipid metabolic process
0.50	GO:0060355	positive regulation of cell adhesion molecule production
0.50	GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin
0.50	GO:0034141	positive regulation of toll-like receptor 3 signaling pathway
0.49	GO:1903044	protein localization to membrane raft
0.49	GO:0070528	protein kinase C signaling
0.49	GO:0034116	positive regulation of heterotypic cell-cell adhesion
0.49	GO:0071360	cellular response to exogenous dsRNA
0.49	GO:1901741	positive regulation of myoblast fusion
0.49	GO:0022617	extracellular matrix disassembly

0.54	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors
0.47	GO:0002020	protease binding
0.47	GO:0016972	thiol oxidase activity
0.44	GO:0046982	protein heterodimerization activity
0.43	GO:0022857	transmembrane transporter activity
0.41	GO:0008168	methyltransferase activity
0.40	GO:0005198	structural molecule activity

0.57	GO:0016600	flotillin complex
0.49	GO:0001931	uropod
0.48	GO:0034451	centriolar satellite
0.48	GO:0044291	cell-cell contact zone
0.47	GO:0005913	cell-cell adherens junction
0.47	GO:0030027	lamellipodium
0.47	GO:0016323	basolateral plasma membrane
0.46	GO:0008180	COP9 signalosome
0.46	GO:0030864	cortical actin cytoskeleton
0.46	GO:0005769	early endosome

0.54

EC:1.3

GO:0016627

tr|T1G120|T1G120_HELRO
Uncharacterized protein
Search

0.39	GO:0035987	endodermal cell differentiation
0.38	GO:0010466	negative regulation of peptidase activity
0.38	GO:0052548	regulation of endopeptidase activity
0.35	GO:0030198	extracellular matrix organization
0.35	GO:0007412	axon target recognition
0.35	GO:0043277	apoptotic cell clearance
0.35	GO:1902284	neuron projection extension involved in neuron projection guidance
0.35	GO:0031290	retinal ganglion cell axon guidance
0.34	GO:0048675	axon extension
0.34	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway

0.49	GO:0042302	structural constituent of cuticle
0.44	GO:0005201	extracellular matrix structural constituent
0.38	GO:0004867	serine-type endopeptidase inhibitor activity
0.35	GO:0042802	identical protein binding
0.34	GO:0005044	scavenger receptor activity
0.34	GO:0001664	G-protein coupled receptor binding
0.33	GO:0005509	calcium ion binding
0.33	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
0.33	GO:0004519	endonuclease activity
0.32	GO:0004601	peroxidase activity

0.70	GO:0005581	collagen trimer
0.44	GO:0005604	basement membrane
0.36	GO:0098645	collagen network
0.34	GO:0042600	chorion
0.33	GO:0005615	extracellular space
0.33	GO:0031514	motile cilium
0.30	GO:0016020	membrane

0.33	EC:3.5.1	GO:0016811
0.32	KEGG:R03532	GO:0004601

tr|T1G121|T1G121_HELRO
Uncharacterized protein
Search

EOGT

0.41	EGF domain specific O-linked N-acetylglucosamine transferase

0.56	GO:0006493	protein O-linked glycosylation
0.45	GO:0008363	larval chitin-based cuticle development
0.43	GO:0018210	peptidyl-threonine modification

0.65	GO:0016757	transferase activity, transferring glycosyl groups
0.44	GO:0140096	catalytic activity, acting on a protein

0.48

GO:0005788

endoplasmic reticulum lumen

0.65

GO:0016757

tr|T1G122|T1G122_HELRO
Uncharacterized protein
Search

0.45	40-residue YVTN family beta-propeller (Fragment)

0.39	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.39	GO:0032836	glomerular basement membrane development
0.39	GO:0007528	neuromuscular junction development
0.38	GO:0007155	cell adhesion
0.37	GO:0035848	oviduct morphogenesis
0.37	GO:0048621	post-embryonic digestive tract morphogenesis
0.36	GO:0060729	intestinal epithelial structure maintenance
0.36	GO:0055013	cardiac muscle cell development
0.35	GO:0010951	negative regulation of endopeptidase activity
0.35	GO:0009405	pathogenesis

0.70	GO:0005201	extracellular matrix structural constituent
0.37	GO:0042302	structural constituent of cuticle
0.36	GO:0004867	serine-type endopeptidase inhibitor activity
0.34	GO:0016301	kinase activity
0.33	GO:0030246	carbohydrate binding
0.33	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.33	GO:0003677	DNA binding

0.69	GO:0005581	collagen trimer
0.62	GO:0005604	basement membrane
0.43	GO:0098645	collagen network
0.39	GO:0031594	neuromuscular junction
0.36	GO:0042383	sarcolemma
0.36	GO:0005615	extracellular space
0.34	GO:0019867	outer membrane
0.30	GO:0016021	integral component of membrane

0.33

GO:0004553

tr|T1G123|T1G123_HELRO
Uncharacterized protein
Search

0.38	GO:0006413	translational initiation
0.36	GO:0008380	RNA splicing
0.35	GO:0006397	mRNA processing
0.34	GO:0006366	transcription by RNA polymerase II

0.59	GO:0003723	RNA binding
0.37	GO:0043175	RNA polymerase core enzyme binding
0.34	GO:0019904	protein domain specific binding

0.45	GO:0005654	nucleoplasm
0.37	GO:0016363	nuclear matrix
0.36	GO:0005681	spliceosomal complex
0.30	GO:0016020	membrane

tr|T1G124|T1G124_HELRO
Uncharacterized protein
Search

0.27	Nucleoside-diphosphate-sugar epimerase

0.54	GO:0006694	steroid biosynthetic process
0.42	GO:0055114	oxidation-reduction process
0.37	GO:0032259	methylation
0.34	GO:0016310	phosphorylation
0.34	GO:0018212	peptidyl-tyrosine modification
0.32	GO:0055085	transmembrane transport
0.32	GO:0043043	peptide biosynthetic process
0.31	GO:0010467	gene expression
0.31	GO:0009059	macromolecule biosynthetic process

0.56	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity
0.56	GO:0050662	coenzyme binding
0.38	GO:0045552	dihydrokaempferol 4-reductase activity
0.37	GO:0008168	methyltransferase activity
0.35	GO:0016301	kinase activity
0.34	GO:0003676	nucleic acid binding
0.34	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.33	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0043168	anion binding

0.32	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.56

EC:1.1.1.145

GO:0003854

tr|T1G125|T1G125_HELRO
Uncharacterized protein
Search

0.38	Collagen triple helix repeat-containing protein (Fragment)

0.41	GO:0030199	collagen fibril organization
0.41	GO:0001957	intramembranous ossification
0.41	GO:0060346	bone trabecula formation
0.41	GO:0032964	collagen biosynthetic process
0.41	GO:0034505	tooth mineralization
0.41	GO:0043589	skin morphogenesis
0.41	GO:0070208	protein heterotrimerization
0.41	GO:0001958	endochondral ossification
0.40	GO:0060351	cartilage development involved in endochondral bone morphogenesis
0.40	GO:0060325	face morphogenesis

0.59	GO:0005201	extracellular matrix structural constituent
0.41	GO:0048407	platelet-derived growth factor binding
0.40	GO:0002020	protease binding
0.38	GO:0042802	identical protein binding
0.37	GO:0004867	serine-type endopeptidase inhibitor activity
0.36	GO:0042302	structural constituent of cuticle
0.35	GO:0005509	calcium ion binding
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0032555	purine ribonucleotide binding

0.64	GO:0005581	collagen trimer
0.46	GO:0031012	extracellular matrix
0.43	GO:0005615	extracellular space
0.39	GO:0099081	supramolecular polymer
0.36	GO:0005694	chromosome
0.34	GO:0005788	endoplasmic reticulum lumen
0.34	GO:1903561	extracellular vesicle
0.34	GO:0031594	neuromuscular junction
0.30	GO:0016020	membrane

tr|T1G126|T1G126_HELRO
Uncharacterized protein
Search

0.65	Respiratory supercomplex factor 1, mitochondrial

0.39	GO:0097250	mitochondrial respiratory chain supercomplex assembly
0.36	GO:0006506	GPI anchor biosynthetic process

0.37

GO:0051377

mannose-ethanolamine phosphotransferase activity

0.37	GO:0005739	mitochondrion
0.36	GO:0044446	intracellular organelle part
0.35	GO:0031090	organelle membrane
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0031975	envelope
0.35	GO:0005783	endoplasmic reticulum
0.30	GO:0031224	intrinsic component of membrane

tr|T1G127|T1G127_HELRO
Uncharacterized protein
Search

RARS

0.65	Arginyl-tRNA synthetase

0.77	GO:0006420	arginyl-tRNA aminoacylation
0.33	GO:0006869	lipid transport
0.33	GO:0006364	rRNA processing
0.33	GO:0008033	tRNA processing
0.33	GO:0032259	methylation

0.78	GO:0004814	arginine-tRNA ligase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0045296	cadherin binding
0.37	GO:0034618	arginine binding
0.35	GO:0000049	tRNA binding
0.33	GO:0008168	methyltransferase activity

0.56	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex
0.48	GO:0005737	cytoplasm
0.47	GO:0005654	nucleoplasm
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.78

EC:6.1.1.19

GO:0004814

tr|T1G128|T1G128_HELRO
Uncharacterized protein
Search

0.58	GO:0038007	netrin-activated signaling pathway
0.49	GO:0048584	positive regulation of response to stimulus
0.49	GO:0072376	protein activation cascade
0.48	GO:0006959	humoral immune response
0.47	GO:0006508	proteolysis
0.46	GO:0002252	immune effector process
0.46	GO:0007229	integrin-mediated signaling pathway
0.46	GO:0002684	positive regulation of immune system process
0.46	GO:0010573	vascular endothelial growth factor production
0.45	GO:0032964	collagen biosynthetic process

0.58	GO:0005042	netrin receptor activity
0.51	GO:0004222	metalloendopeptidase activity
0.44	GO:0046872	metal ion binding
0.36	GO:0004930	G-protein coupled receptor activity
0.33	GO:0008201	heparin binding
0.33	GO:0004970	ionotropic glutamate receptor activity
0.33	GO:0008061	chitin binding
0.33	GO:0004867	serine-type endopeptidase inhibitor activity
0.33	GO:0030246	carbohydrate binding
0.33	GO:0004252	serine-type endopeptidase activity

0.50	GO:0005579	membrane attack complex
0.48	GO:0005576	extracellular region
0.34	GO:0009986	cell surface
0.34	GO:0031982	vesicle
0.32	GO:0005829	cytosol

0.51

GO:0004222

tr|T1G129|T1G129_HELRO
Uncharacterized protein
Search

0.46	Mitochondrial import inner membrane translocase subunit Tim9

0.65	GO:0015031	protein transport
0.59	GO:0071456	cellular response to hypoxia
0.41	GO:0072655	establishment of protein localization to mitochondrion
0.41	GO:0006839	mitochondrial transport
0.40	GO:0007005	mitochondrion organization
0.39	GO:0046907	intracellular transport
0.36	GO:0090150	establishment of protein localization to membrane
0.36	GO:0055085	transmembrane transport
0.35	GO:0061024	membrane organization

0.54	GO:0046872	metal ion binding
0.39	GO:0008565	protein transporter activity
0.38	GO:1904680	peptide transmembrane transporter activity
0.38	GO:0022884	macromolecule transmembrane transporter activity
0.36	GO:0015399	primary active transmembrane transporter activity

0.61	GO:0005739	mitochondrion
0.41	GO:0031970	organelle envelope lumen
0.38	GO:1990351	transporter complex
0.37	GO:0098796	membrane protein complex
0.37	GO:0019866	organelle inner membrane

tr|T1G130|T1G130_HELRO
Uncharacterized protein
Search

0.44	probable RNA-binding protein EIF1AD

0.72

GO:0006413

translational initiation

0.72

GO:0003743

translation initiation factor activity

0.46

GO:0005634

nucleus

tr|T1G131|T1G131_HELRO
Uncharacterized protein
Search

tr|T1G132|T1G132_HELRO
Uncharacterized protein
Search

PAQR3

0.95	Progestin and adipoQ receptor family member IIIb

0.53	GO:0033137	negative regulation of peptidyl-serine phosphorylation
0.52	GO:0034067	protein localization to Golgi apparatus
0.52	GO:0010977	negative regulation of neuron projection development
0.51	GO:0043407	negative regulation of MAP kinase activity
0.34	GO:0000165	MAPK cascade
0.34	GO:0033211	adiponectin-activated signaling pathway
0.33	GO:0000281	mitotic cytokinesis
0.33	GO:0006897	endocytosis
0.32	GO:0006886	intracellular protein transport
0.32	GO:0006465	signal peptide processing

0.42	GO:0004872	receptor activity
0.33	GO:0042562	hormone binding
0.33	GO:0005515	protein binding
0.33	GO:0035091	phosphatidylinositol binding
0.33	GO:0016301	kinase activity
0.32	GO:0050660	flavin adenine dinucleotide binding
0.32	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors
0.32	GO:0005506	iron ion binding
0.32	GO:0008233	peptidase activity

0.46	GO:0005794	Golgi apparatus
0.35	GO:0098588	bounding membrane of organelle
0.34	GO:0031984	organelle subcompartment
0.32	GO:1905368	peptidase complex
0.32	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.32	GO:0044432	endoplasmic reticulum part
0.32	GO:0005886	plasma membrane
0.32	GO:0098796	membrane protein complex
0.30	GO:0016021	integral component of membrane

0.32

EC:1.1

GO:0016614

tr|T1G133|T1G133_HELRO
Uncharacterized protein
Search

0.58	GO:0001558	regulation of cell growth
0.40	GO:0006357	regulation of transcription by RNA polymerase II
0.39	GO:0071773	cellular response to BMP stimulus
0.39	GO:0090101	negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
0.39	GO:0051216	cartilage development
0.39	GO:0009953	dorsal/ventral pattern formation
0.39	GO:0090288	negative regulation of cellular response to growth factor stimulus
0.39	GO:0030178	negative regulation of Wnt signaling pathway
0.38	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
0.38	GO:0035335	peptidyl-tyrosine dephosphorylation

0.60	GO:0005520	insulin-like growth factor binding
0.39	GO:0008144	drug binding
0.39	GO:0097367	carbohydrate derivative binding
0.39	GO:0003676	nucleic acid binding
0.39	GO:0030554	adenyl nucleotide binding
0.38	GO:0004725	protein tyrosine phosphatase activity
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0004386	helicase activity
0.38	GO:0098772	molecular function regulator
0.37	GO:0003700	DNA binding transcription factor activity

0.50	GO:0005576	extracellular region
0.37	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.38	EC:3.1.3.48	GO:0004725
0.36	KEGG:R03532	GO:0004601

tr|T1G134|T1G134_HELRO
Uncharacterized protein
Search

0.86	Cytochrome P450, subfamily IIIA, polypeptide 4

0.53	GO:0055114	oxidation-reduction process
0.36	GO:0002933	lipid hydroxylation
0.36	GO:0010628	positive regulation of gene expression
0.35	GO:0070988	demethylation
0.35	GO:0017085	response to insecticide
0.34	GO:0008202	steroid metabolic process
0.33	GO:0017144	drug metabolic process
0.32	GO:0006813	potassium ion transport
0.32	GO:0045454	cell redox homeostasis

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.67	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.36	GO:0003958	NADPH-hemoprotein reductase activity
0.35	GO:0032451	demethylase activity
0.34	GO:0010181	FMN binding
0.34	GO:0005509	calcium ion binding
0.32	GO:0050660	flavin adenine dinucleotide binding
0.32	GO:0004386	helicase activity

0.38	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

0.68

GO:0016705

tr|T1G135|T1G135_HELRO
Uncharacterized protein
Search

0.56	GO:0007219	Notch signaling pathway
0.52	GO:0007275	multicellular organism development
0.51	GO:0030154	cell differentiation
0.49	GO:0050793	regulation of developmental process
0.45	GO:0051171	regulation of nitrogen compound metabolic process
0.45	GO:0060255	regulation of macromolecule metabolic process
0.45	GO:0080090	regulation of primary metabolic process
0.44	GO:0031323	regulation of cellular metabolic process
0.44	GO:0007160	cell-matrix adhesion
0.44	GO:0030198	extracellular matrix organization

0.70	GO:0005509	calcium ion binding
0.50	GO:0005201	extracellular matrix structural constituent
0.49	GO:0004872	receptor activity
0.41	GO:0016504	peptidase activator activity
0.41	GO:0043237	laminin-1 binding
0.41	GO:0043394	proteoglycan binding
0.40	GO:0005518	collagen binding
0.37	GO:0070051	fibrinogen binding
0.36	GO:0001968	fibronectin binding
0.36	GO:0050431	transforming growth factor beta binding

0.51	GO:0005578	proteinaceous extracellular matrix
0.41	GO:0044420	extracellular matrix component
0.40	GO:0005615	extracellular space
0.35	GO:0071944	cell periphery
0.34	GO:0043234	protein complex
0.34	GO:0005902	microvillus
0.33	GO:0005913	cell-cell adherens junction
0.33	GO:0005634	nucleus
0.32	GO:1903561	extracellular vesicle
0.30	GO:0016020	membrane

0.33

EC:1.11.1.6

GO:0004096

tr|T1G136|T1G136_HELRO
Uncharacterized protein
Search

0.50	GO:0010729	positive regulation of hydrogen peroxide biosynthetic process
0.49	GO:0009789	positive regulation of abscisic acid-activated signaling pathway
0.47	GO:0016567	protein ubiquitination
0.44	GO:0009737	response to abscisic acid
0.44	GO:0009414	response to water deprivation
0.41	GO:0009630	gravitropism
0.38	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.35	GO:1903506	regulation of nucleic acid-templated transcription
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression

0.48	GO:0016874	ligase activity
0.47	GO:0004842	ubiquitin-protein transferase activity
0.46	GO:0008270	zinc ion binding
0.39	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.38	GO:0061659	ubiquitin-like protein ligase activity
0.36	GO:0005515	protein binding
0.34	GO:0003676	nucleic acid binding

0.41	GO:0009501	amyloplast
0.40	GO:0005829	cytosol
0.35	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.48	EC:6	GO:0016874
0.47	KEGG:R03876	GO:0004842

tr|T1G137|T1G137_HELRO
Uncharacterized protein
Search

CABZ01088365.1

0.67	Rho GTPase activating protein 9

0.71	GO:0043547	positive regulation of GTPase activity
0.61	GO:0007165	signal transduction
0.34	GO:0016192	vesicle-mediated transport
0.34	GO:0002283	neutrophil activation involved in immune response
0.34	GO:0002446	neutrophil mediated immunity
0.34	GO:0098657	import into cell
0.33	GO:0051056	regulation of small GTPase mediated signal transduction
0.33	GO:0032940	secretion by cell

0.72	GO:0005096	GTPase activator activity
0.52	GO:0005543	phospholipid binding
0.34	GO:0017124	SH3 domain binding

0.36	GO:0005829	cytosol
0.36	GO:0031974	membrane-enclosed lumen
0.35	GO:0044428	nuclear part
0.33	GO:0030141	secretory granule
0.33	GO:0044433	cytoplasmic vesicle part
0.32	GO:0005576	extracellular region
0.30	GO:0016020	membrane

tr|T1G138|T1G138_HELRO
Uncharacterized protein
Search

PIGA

0.88	Phosphatidylinositol N-acetylglucosaminyltransferase subunit A

0.78	GO:0006506	GPI anchor biosynthetic process
0.52	GO:1990830	cellular response to leukemia inhibitory factor
0.36	GO:0046854	phosphatidylinositol phosphorylation
0.33	GO:0009893	positive regulation of metabolic process
0.33	GO:0035556	intracellular signal transduction
0.33	GO:0006470	protein dephosphorylation
0.33	GO:0016567	protein ubiquitination

0.54	GO:0016757	transferase activity, transferring glycosyl groups
0.36	GO:0016307	phosphatidylinositol phosphate kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0004721	phosphoprotein phosphatase activity
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005515	protein binding

0.58	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex
0.30	GO:0016021	integral component of membrane

0.54

GO:0016757

tr|T1G139|T1G139_HELRO
Uncharacterized protein
Search

GMFB

0.92	Glia maturation factor gamma

0.84	GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation
0.63	GO:2000249	regulation of actin cytoskeleton reorganization
0.50	GO:0071846	actin filament debranching
0.50	GO:0007612	learning
0.49	GO:0007626	locomotory behavior
0.40	GO:0010469	regulation of receptor activity
0.36	GO:0006469	negative regulation of protein kinase activity
0.35	GO:0043085	positive regulation of catalytic activity
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0006468	protein phosphorylation

0.84	GO:0071933	Arp2/3 complex binding
0.71	GO:0003779	actin binding
0.40	GO:0008083	growth factor activity
0.36	GO:0004860	protein kinase inhibitor activity
0.35	GO:0008047	enzyme activator activity
0.33	GO:0004871	signal transducer activity

0.44	GO:0005622	intracellular
0.35	GO:0031983	vesicle lumen
0.33	GO:0012505	endomembrane system
0.33	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

tr|T1G140|T1G140_HELRO
Uncharacterized protein
Search

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.52	GO:0007420	brain development
0.51	GO:0030182	neuron differentiation
0.49	GO:0061351	neural precursor cell proliferation
0.48	GO:0009952	anterior/posterior pattern specification
0.48	GO:0072001	renal system development
0.47	GO:0048562	embryonic organ morphogenesis
0.47	GO:0090596	sensory organ morphogenesis

0.64	GO:0043565	sequence-specific DNA binding
0.42	GO:0005351	sugar:proton symporter activity
0.38	GO:0003700	DNA binding transcription factor activity
0.35	GO:0001012	RNA polymerase II regulatory region DNA binding
0.35	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding
0.35	GO:0003690	double-stranded DNA binding
0.34	GO:0031490	chromatin DNA binding
0.34	GO:0035326	enhancer binding
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.41	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1G141|T1G141_HELRO
Uncharacterized protein
Search

0.53	BTB/POZ domain-containing protein 10

0.73	GO:0050975	sensory perception of touch
0.53	GO:1901215	negative regulation of neuron death
0.50	GO:0042327	positive regulation of phosphorylation
0.46	GO:0043413	macromolecule glycosylation
0.46	GO:0009101	glycoprotein biosynthetic process
0.42	GO:0044342	type B pancreatic cell proliferation
0.41	GO:0036211	protein modification process
0.39	GO:0044267	cellular protein metabolic process
0.39	GO:0035023	regulation of Rho protein signal transduction
0.38	GO:0006313	transposition, DNA-mediated

0.49	GO:0004576	oligosaccharyl transferase activity
0.45	GO:0004370	glycerol kinase activity
0.39	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.38	GO:0004803	transposase activity
0.35	GO:0003677	DNA binding

0.53	GO:0001650	fibrillar center
0.38	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.49	EC:2.4.1	GO:0004576
0.45	KEGG:R00847	GO:0004370

tr|T1G142|T1G142_HELRO
Uncharacterized protein
Search

tr|T1G143|T1G143_HELRO
Uncharacterized protein
Search

tr|T1G144|T1G144_HELRO
Uncharacterized protein
Search

0.76	GO:0070588	calcium ion transmembrane transport
0.69	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.38	GO:0006874	cellular calcium ion homeostasis

0.80	GO:0005388	calcium-transporting ATPase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0030165	PDZ domain binding

0.35	GO:0005887	integral component of plasma membrane
0.33	GO:0043231	intracellular membrane-bounded organelle

0.80

EC:3.6.3.8

GO:0005388

tr|T1G145|T1G145_HELRO
Uncharacterized protein
Search

0.75	GO:0035335	peptidyl-tyrosine dephosphorylation
0.55	GO:0071364	cellular response to epidermal growth factor stimulus
0.53	GO:0042058	regulation of epidermal growth factor receptor signaling pathway
0.39	GO:0040007	growth
0.39	GO:0031099	regeneration
0.38	GO:0042060	wound healing
0.37	GO:0009888	tissue development
0.35	GO:2000587	negative regulation of platelet-derived growth factor receptor-beta signaling pathway
0.35	GO:0031669	cellular response to nutrient levels
0.35	GO:0038128	ERBB2 signaling pathway

0.75	GO:0004725	protein tyrosine phosphatase activity
0.51	GO:0017124	SH3 domain binding
0.35	GO:0033549	MAP kinase phosphatase activity

0.55	GO:0002102	podosome
0.46	GO:0005829	cytosol
0.36	GO:0005925	focal adhesion
0.35	GO:0042995	cell projection
0.34	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.75

GO:0004725

tr|T1G146|T1G146_HELRO
Uncharacterized protein
Search

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.44	GO:0007210	serotonin receptor signaling pathway
0.42	GO:0007610	behavior
0.40	GO:0019933	cAMP-mediated signaling
0.39	GO:0050890	cognition
0.38	GO:0070098	chemokine-mediated signaling pathway
0.36	GO:0006935	chemotaxis
0.35	GO:0007267	cell-cell signaling
0.35	GO:1900101	regulation of endoplasmic reticulum unfolded protein response
0.35	GO:0002304	gamma-delta intraepithelial T cell differentiation

0.72	GO:0004930	G-protein coupled receptor activity
0.57	GO:0030594	neurotransmitter receptor activity
0.44	GO:0099589	serotonin receptor activity
0.39	GO:0001653	peptide receptor activity
0.38	GO:0004896	cytokine receptor activity

0.51	GO:0005887	integral component of plasma membrane
0.34	GO:0061827	sperm head
0.34	GO:0097225	sperm midpiece
0.33	GO:0009986	cell surface
0.33	GO:0005622	intracellular
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0043227	membrane-bounded organelle

tr|T1G147|T1G147_HELRO
Uncharacterized protein
Search

0.69

Filamin-A

0.34	GO:0008302	female germline ring canal formation, actin assembly
0.33	GO:0045614	negative regulation of plasmatocyte differentiation
0.33	GO:0035203	regulation of lamellocyte differentiation
0.33	GO:0030708	germarium-derived female germ-line cyst encapsulation
0.33	GO:0007303	cytoplasmic transport, nurse cell to oocyte
0.33	GO:0048149	behavioral response to ethanol
0.33	GO:0007616	long-term memory
0.33	GO:0048581	negative regulation of post-embryonic development
0.33	GO:0008045	motor neuron axon guidance
0.33	GO:0045214	sarcomere organization

0.74	GO:0003779	actin binding
0.33	GO:0032403	protein complex binding
0.32	GO:0030246	carbohydrate binding

0.34	GO:0035182	female germline ring canal outer rim
0.34	GO:0035183	female germline ring canal inner rim
0.33	GO:0045179	apical cortex
0.33	GO:0070938	contractile ring
0.33	GO:0030018	Z disc
0.33	GO:0005884	actin filament
0.33	GO:0048471	perinuclear region of cytoplasm
0.32	GO:0005829	cytosol
0.32	GO:0005634	nucleus
0.32	GO:0005886	plasma membrane

tr|T1G148|T1G148_HELRO
Uncharacterized protein
Search

tr|T1G149|T1G149_HELRO
Uncharacterized protein
Search

0.49	Glutathione gamma-glutamylcysteinyltransferase

0.85	GO:0046937	phytochelatin metabolic process
0.77	GO:0010038	response to metal ion
0.74	GO:0044550	secondary metabolite biosynthetic process
0.60	GO:0043043	peptide biosynthetic process
0.41	GO:0061687	detoxification of inorganic compound
0.37	GO:0006950	response to stress
0.37	GO:0042344	indole glucosinolate catabolic process
0.36	GO:0071241	cellular response to inorganic substance
0.36	GO:0052543	callose deposition in cell wall
0.36	GO:1901684	arsenate ion transmembrane transport

0.85	GO:0016756	glutathione gamma-glutamylcysteinyltransferase activity
0.54	GO:0046872	metal ion binding
0.36	GO:0015446	ATPase-coupled arsenite transmembrane transporter activity
0.33	GO:0042302	structural constituent of cuticle

0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.85

EC:2.3.2.15

GO:0016756

tr|T1G150|T1G150_HELRO
Uncharacterized protein
Search

0.48	GO:0016567	protein ubiquitination
0.44	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.34	GO:1901666	positive regulation of NAD+ ADP-ribosyltransferase activity
0.34	GO:2000646	positive regulation of receptor catabolic process
0.34	GO:1902966	positive regulation of protein localization to early endosome
0.34	GO:0035563	positive regulation of chromatin binding
0.34	GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining
0.34	GO:0051444	negative regulation of ubiquitin-protein transferase activity
0.34	GO:0002230	positive regulation of defense response to virus by host
0.34	GO:0008333	endosome to lysosome transport

0.49	GO:0008270	zinc ion binding
0.48	GO:0061630	ubiquitin protein ligase activity
0.45	GO:0016874	ligase activity
0.34	GO:0097677	STAT family protein binding
0.33	GO:0042393	histone binding
0.33	GO:0044389	ubiquitin-like protein ligase binding
0.33	GO:0008047	enzyme activator activity
0.33	GO:0004857	enzyme inhibitor activity
0.33	GO:0016817	hydrolase activity, acting on acid anhydrides
0.32	GO:0032559	adenyl ribonucleotide binding

0.33	GO:0044428	nuclear part
0.33	GO:0005769	early endosome
0.33	GO:0005764	lysosome
0.33	GO:0031461	cullin-RING ubiquitin ligase complex
0.33	GO:0005886	plasma membrane
0.33	GO:0005829	cytosol
0.32	GO:0031974	membrane-enclosed lumen
0.32	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

0.45

GO:0016874

tr|T1G151|T1G151_HELRO
Uncharacterized protein
Search

0.77	Hyperpolarization-activated cyclic nucleotide-modulated cation channel splice variant ABs-II

0.69	GO:0071805	potassium ion transmembrane transport
0.61	GO:0043269	regulation of ion transport
0.60	GO:0034762	regulation of transmembrane transport
0.46	GO:0016057	regulation of membrane potential in photoreceptor cell
0.46	GO:0007637	proboscis extension reflex
0.46	GO:0071632	optomotor response
0.46	GO:0050802	circadian sleep/wake cycle, sleep
0.46	GO:0071484	cellular response to light intensity
0.45	GO:0045938	positive regulation of circadian sleep/wake cycle, sleep
0.45	GO:0050433	regulation of catecholamine secretion

0.73	GO:0005249	voltage-gated potassium channel activity
0.35	GO:0004692	cGMP-dependent protein kinase activity
0.33	GO:0003677	DNA binding
0.32	GO:1901265	nucleoside phosphate binding
0.32	GO:0036094	small molecule binding

0.36	GO:0005887	integral component of plasma membrane
0.33	GO:0005634	nucleus

0.35

EC:2.7.11.12

GO:0004692

tr|T1G152|T1G152_HELRO
Uncharacterized protein
Search

VPS53

0.85	Vacuolar protein sorting-associated protein 53

0.81	GO:0042147	retrograde transport, endosome to Golgi
0.74	GO:0032456	endocytic recycling
0.71	GO:0007041	lysosomal transport
0.51	GO:0015031	protein transport

0.40

GO:0005515

protein binding

0.86	GO:0000938	GARP complex
0.79	GO:1990745	EARP complex
0.69	GO:0005829	cytosol
0.67	GO:0005802	trans-Golgi network
0.67	GO:0048471	perinuclear region of cytoplasm
0.59	GO:0010008	endosome membrane
0.43	GO:0000139	Golgi membrane

tr|T1G153|T1G153_HELRO
Protein YIPF
Search

YIPF7

0.88	Yip1 domain family member 7

0.30

GO:0044425

membrane part

tr|T1G154|T1G154_HELRO
Uncharacterized protein
Search

0.49	Anaphase-promoting complex subunit 13

0.69	GO:0046854	phosphatidylinositol phosphorylation
0.43	GO:0006458	'de novo' protein folding
0.43	GO:0042147	retrograde transport, endosome to Golgi
0.42	GO:0061077	chaperone-mediated protein folding

0.74	GO:0016307	phosphatidylinositol phosphate kinase activity
0.52	GO:0046872	metal ion binding
0.51	GO:0032559	adenyl ribonucleotide binding
0.50	GO:0008144	drug binding
0.50	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0044183	protein binding involved in protein folding
0.41	GO:0051082	unfolded protein binding

0.42	GO:0010008	endosome membrane
0.40	GO:0005829	cytosol

0.74

GO:0016307

tr|T1G155|T1G155_HELRO
Uncharacterized protein
Search

0.63	Sex-lethal

0.43	GO:0000380	alternative mRNA splicing, via spliceosome
0.42	GO:0007530	sex determination
0.40	GO:0051239	regulation of multicellular organismal process
0.39	GO:0050793	regulation of developmental process
0.39	GO:0048518	positive regulation of biological process
0.38	GO:0043489	RNA stabilization
0.38	GO:0043488	regulation of mRNA stability
0.37	GO:1903312	negative regulation of mRNA metabolic process
0.37	GO:0007275	multicellular organism development
0.36	GO:0060964	regulation of gene silencing by miRNA

0.59	GO:0003723	RNA binding
0.35	GO:0019901	protein kinase binding
0.35	GO:0042803	protein homodimerization activity

0.35	GO:0005938	cell cortex
0.35	GO:0005634	nucleus
0.35	GO:1990904	ribonucleoprotein complex
0.34	GO:0005829	cytosol
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.33	GO:0019013	viral nucleocapsid
0.30	GO:0016020	membrane

tr|T1G156|T1G156_HELRO
Uncharacterized protein
Search

SLC8A1

0.57	Sodium calcium exchanger membrane region and Na-Ca exchanger integrin-beta4 domain containing protein

0.76	GO:0035725	sodium ion transmembrane transport
0.76	GO:0006816	calcium ion transport
0.59	GO:0007154	cell communication
0.34	GO:0023052	signaling
0.34	GO:0051716	cellular response to stimulus
0.33	GO:0006468	protein phosphorylation
0.33	GO:0065007	biological regulation

0.84	GO:0005432	calcium:sodium antiporter activity
0.34	GO:0004672	protein kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0008270	zinc ion binding

0.30

GO:0016020

membrane

tr|T1G157|T1G157_HELRO
Uncharacterized protein
Search

0.46	GO:0048488	synaptic vesicle endocytosis
0.36	GO:0009235	cobalamin metabolic process
0.32	GO:0055114	oxidation-reduction process

0.32	GO:0008270	zinc ion binding
0.32	GO:0016491	oxidoreductase activity

0.43	GO:0045202	synapse
0.30	GO:0044425	membrane part
0.30	GO:0005623	cell

0.32

GO:0016491

tr|T1G158|T1G158_HELRO
Uncharacterized protein
Search

0.69	PCTP-like protein (inferred by orthology to a human protein)

0.41	GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway
0.41	GO:0032782	bile acid secretion
0.34	GO:0006869	lipid transport
0.32	GO:0016043	cellular component organization

0.72	GO:0008289	lipid binding
0.33	GO:0003779	actin binding

0.43	GO:0046581	intercellular canaliculus
0.42	GO:0005902	microvillus
0.38	GO:0005829	cytosol
0.34	GO:0031514	motile cilium
0.30	GO:0044425	membrane part

tr|T1G159|T1G159_HELRO
Uncharacterized protein
Search

0.60	GO:0007166	cell surface receptor signaling pathway
0.59	GO:0044344	cellular response to fibroblast growth factor stimulus
0.57	GO:0090175	regulation of establishment of planar polarity
0.57	GO:0060026	convergent extension
0.57	GO:0001736	establishment of planar polarity
0.57	GO:0006468	protein phosphorylation
0.57	GO:0008284	positive regulation of cell proliferation
0.56	GO:0018212	peptidyl-tyrosine modification
0.53	GO:0198738	cell-cell signaling by wnt
0.50	GO:0060484	lung-associated mesenchyme development

0.61	GO:0005007	fibroblast growth factor-activated receptor activity
0.59	GO:1904929	coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway
0.50	GO:0030554	adenyl nucleotide binding
0.49	GO:0097367	carbohydrate derivative binding
0.49	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0008144	drug binding
0.44	GO:0017134	fibroblast growth factor binding
0.44	GO:0005509	calcium ion binding
0.43	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.43	GO:0017048	Rho GTPase binding

0.50	GO:0031226	intrinsic component of plasma membrane
0.46	GO:0030054	cell junction
0.42	GO:0030133	transport vesicle
0.41	GO:0005794	Golgi apparatus
0.41	GO:0005783	endoplasmic reticulum
0.39	GO:0005604	basement membrane
0.39	GO:0031430	M band
0.37	GO:0005938	cell cortex
0.36	GO:0009986	cell surface
0.36	GO:0048471	perinuclear region of cytoplasm

0.34	EC:2.7.1.153	GO:0046934
0.34	KEGG:R04545	GO:0046934

tr|T1G160|T1G160_HELRO
Uncharacterized protein
Search

SNRPD2

0.84	Small nuclear ribonucleoprotein D2 polypeptide

0.74	GO:0008380	RNA splicing
0.47	GO:0022618	ribonucleoprotein complex assembly
0.46	GO:0006397	mRNA processing
0.34	GO:0051170	nuclear import
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.38	GO:1990446	U1 snRNP binding
0.34	GO:0043565	sequence-specific DNA binding
0.34	GO:0003700	DNA binding transcription factor activity
0.33	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.78	GO:0030532	small nuclear ribonucleoprotein complex
0.61	GO:0019013	viral nucleocapsid
0.50	GO:0071013	catalytic step 2 spliceosome
0.48	GO:0071011	precatalytic spliceosome
0.47	GO:0034709	methylosome
0.47	GO:0034715	pICln-Sm protein complex
0.46	GO:0034719	SMN-Sm protein complex
0.46	GO:0005689	U12-type spliceosomal complex
0.43	GO:0005684	U2-type spliceosomal complex
0.41	GO:0005829	cytosol

tr|T1G161|T1G161_HELRO
Uncharacterized protein
Search

0.64	TRP channel protein nanchung

0.60	GO:0034220	ion transmembrane transport
0.53	GO:0048060	negative gravitaxis
0.51	GO:0050884	neuromuscular process controlling posture
0.51	GO:0010996	response to auditory stimulus
0.51	GO:0001964	startle response
0.51	GO:0007628	adult walking behavior
0.50	GO:0009270	response to humidity
0.48	GO:0007605	sensory perception of sound
0.48	GO:0050976	detection of mechanical stimulus involved in sensory perception of touch
0.42	GO:0043052	thermotaxis

0.70	GO:0005216	ion channel activity
0.38	GO:0015085	calcium ion transmembrane transporter activity
0.33	GO:0005515	protein binding
0.32	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.36	GO:0034703	cation channel complex
0.36	GO:0005887	integral component of plasma membrane

tr|T1G162|T1G162_HELRO
Uncharacterized protein
Search

tr|T1G163|T1G163_HELRO
Uncharacterized protein
Search

0.63	GO:0006629	lipid metabolic process
0.54	GO:0071926	endocannabinoid signaling pathway
0.50	GO:0098920	retrograde trans-synaptic signaling by lipid
0.49	GO:0099542	trans-synaptic signaling by endocannabinoid
0.48	GO:0007216	G-protein coupled glutamate receptor signaling pathway
0.47	GO:0007405	neuroblast proliferation
0.47	GO:0006690	icosanoid metabolic process
0.44	GO:0042136	neurotransmitter biosynthetic process
0.43	GO:0036269	swimming behavior
0.43	GO:0007634	optokinetic behavior

0.51	GO:0016787	hydrolase activity
0.33	GO:0046872	metal ion binding
0.32	GO:0051537	2 iron, 2 sulfur cluster binding

0.49	GO:0043196	varicosity
0.45	GO:0045211	postsynaptic membrane
0.33	GO:0043025	neuronal cell body
0.32	GO:0005759	mitochondrial matrix
0.30	GO:0016021	integral component of membrane

0.51

GO:0016787

tr|T1G164|T1G164_HELRO
Uncharacterized protein
Search

VIPR2

0.87	Vasoactive intestinal polypeptide receptor 2

0.70	GO:0007166	cell surface receptor signaling pathway
0.69	GO:0007186	G-protein coupled receptor signaling pathway
0.41	GO:0007190	activation of adenylate cyclase activity
0.40	GO:0048662	negative regulation of smooth muscle cell proliferation
0.34	GO:0007267	cell-cell signaling

0.84

GO:0004999

vasoactive intestinal polypeptide receptor activity

0.47	GO:0005886	plasma membrane
0.36	GO:0043235	receptor complex
0.34	GO:0005929	cilium
0.30	GO:0044425	membrane part

tr|T1G165|T1G165_HELRO
Uncharacterized protein
Search

tr|T1G166|T1G166_HELRO
Transporter
Search

0.49	Sodium-dependent dopamine transporter

0.74	GO:0006836	neurotransmitter transport
0.55	GO:0042066	perineurial glial growth
0.54	GO:0055085	transmembrane transport
0.52	GO:0019226	transmission of nerve impulse
0.42	GO:0007165	signal transduction
0.41	GO:0015718	monocarboxylic acid transport
0.40	GO:0006865	amino acid transport
0.34	GO:0015734	taurine transport
0.33	GO:0006812	cation transport

0.77	GO:0005328	neurotransmitter:sodium symporter activity
0.55	GO:0005034	osmosensor activity
0.50	GO:0009881	photoreceptor activity
0.43	GO:0015185	gamma-aminobutyric acid transmembrane transporter activity
0.43	GO:0015355	secondary active monocarboxylate transmembrane transporter activity
0.42	GO:0005343	organic acid:sodium symporter activity
0.42	GO:0015296	anion:cation symporter activity
0.41	GO:0005416	amino acid:cation symporter activity
0.34	GO:0005368	taurine transmembrane transporter activity
0.34	GO:0015193	L-proline transmembrane transporter activity

0.44	GO:0005887	integral component of plasma membrane
0.34	GO:0031526	brush border membrane

tr|T1G167|T1G167_HELRO
Uncharacterized protein
Search

RBM24

0.57	RNA binding motif protein 24

0.58	GO:0010830	regulation of myotube differentiation
0.52	GO:0043488	regulation of mRNA stability
0.49	GO:0043484	regulation of RNA splicing
0.41	GO:0006397	mRNA processing
0.41	GO:0032502	developmental process
0.40	GO:0008380	RNA splicing
0.38	GO:0032956	regulation of actin cytoskeleton organization
0.38	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
0.38	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
0.38	GO:0040012	regulation of locomotion

0.59	GO:0003723	RNA binding
0.34	GO:0003779	actin binding

0.46	GO:0005654	nucleoplasm
0.45	GO:0005829	cytosol
0.36	GO:0030529	intracellular ribonucleoprotein complex
0.35	GO:0005852	eukaryotic translation initiation factor 3 complex
0.30	GO:0031224	intrinsic component of membrane

tr|T1G168|T1G168_HELRO
Uncharacterized protein
Search

tr|T1G169|T1G169_HELRO
Uncharacterized protein
Search

0.61	Galactosyltransferase

0.60	GO:0005975	carbohydrate metabolic process
0.46	GO:0006688	glycosphingolipid biosynthetic process
0.43	GO:0006044	N-acetylglucosamine metabolic process
0.38	GO:0048840	otolith development
0.37	GO:0009950	dorsal/ventral axis specification
0.37	GO:0030513	positive regulation of BMP signaling pathway
0.37	GO:0030166	proteoglycan biosynthetic process

0.65	GO:0016757	transferase activity, transferring glycosyl groups
0.44	GO:0140103	catalytic activity, acting on a glycoprotein

0.41	GO:0005794	Golgi apparatus
0.30	GO:0016020	membrane

0.65

GO:0016757

tr|T1G170|T1G170_HELRO
Uncharacterized protein
Search

NOL10

0.92	Nucleolar protein 10

0.33

GO:0003723

RNA binding

0.61	GO:0005634	nucleus
0.46	GO:0031974	membrane-enclosed lumen
0.43	GO:0043232	intracellular non-membrane-bounded organelle
0.42	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

tr|T1G171|T1G171_HELRO
Uncharacterized protein
Search

0.56

GO:0016579

protein deubiquitination

0.56

GO:0036459

thiol-dependent ubiquitinyl hydrolase activity

0.30

GO:0031224

intrinsic component of membrane

0.56

GO:0036459

tr|T1G172|T1G172_HELRO
Uncharacterized protein
Search

0.87	Histone-arginine methyltransferase CARMER

0.73	GO:0008213	protein alkylation
0.67	GO:0043414	macromolecule methylation
0.46	GO:0018195	peptidyl-arginine modification
0.44	GO:0048742	regulation of skeletal muscle fiber development
0.44	GO:0016570	histone modification
0.41	GO:0006338	chromatin remodeling
0.38	GO:1903506	regulation of nucleic acid-templated transcription
0.38	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.38	GO:0010468	regulation of gene expression
0.37	GO:0006351	transcription, DNA-templated

0.63	GO:0008168	methyltransferase activity
0.39	GO:0140096	catalytic activity, acting on a protein
0.36	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.36	GO:0070577	lysine-acetylated histone binding
0.35	GO:0044212	transcription regulatory region DNA binding

0.40	GO:0035097	histone methyltransferase complex
0.39	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.63

GO:0008168

tr|T1G173|T1G173_HELRO
Uncharacterized protein
Search

HTR4

0.72	Octopamine receptor

0.76	GO:0032098	regulation of appetite
0.74	GO:0098664	G-protein coupled serotonin receptor signaling pathway
0.68	GO:0007268	chemical synaptic transmission
0.45	GO:0007214	gamma-aminobutyric acid signaling pathway
0.42	GO:0071875	adrenergic receptor signaling pathway
0.35	GO:0007187	G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
0.34	GO:0007218	neuropeptide signaling pathway
0.34	GO:0019933	cAMP-mediated signaling
0.34	GO:0050890	cognition
0.32	GO:0018108	peptidyl-tyrosine phosphorylation

0.75	GO:0008227	G-protein coupled amine receptor activity
0.74	GO:0099589	serotonin receptor activity
0.71	GO:0099528	G-protein coupled neurotransmitter receptor activity
0.35	GO:0004983	neuropeptide Y receptor activity
0.33	GO:0005515	protein binding
0.33	GO:0004715	non-membrane spanning protein tyrosine kinase activity

0.59	GO:0005887	integral component of plasma membrane
0.37	GO:0005768	endosome

0.33

GO:0004715

tr|T1G174|T1G174_HELRO
Uncharacterized protein
Search

tr|T1G175|T1G175_HELRO
Receptor expression-enhancing protein
Search

0.49	Receptor expression-enhancing protein (Fragment)

0.52	GO:0032596	protein transport into membrane raft
0.51	GO:0050916	sensory perception of sweet taste
0.50	GO:0071786	endoplasmic reticulum tubular network organization
0.50	GO:0050913	sensory perception of bitter taste
0.48	GO:0032386	regulation of intracellular transport

0.53

GO:0031883

taste receptor binding

0.49	GO:0005881	cytoplasmic microtubule
0.45	GO:0005789	endoplasmic reticulum membrane
0.43	GO:0005887	integral component of plasma membrane
0.34	GO:0070062	extracellular exosome

tr|T1G176|T1G176_HELRO
Uncharacterized protein
Search

0.41	GO:0010609	mRNA localization resulting in posttranscriptional regulation of gene expression
0.40	GO:0061157	mRNA destabilization
0.37	GO:0000381	regulation of alternative mRNA splicing, via spliceosome

0.59	GO:0003723	RNA binding
0.35	GO:0046872	metal ion binding

0.42	GO:0048471	perinuclear region of cytoplasm
0.40	GO:0005634	nucleus
0.37	GO:0005829	cytosol
0.37	GO:0043233	organelle lumen
0.35	GO:0044446	intracellular organelle part

tr|T1G177|T1G177_HELRO
Uncharacterized protein
Search

FAM96B

0.65	Mitotic spindle-associated MMXD complex subunit MIP18

0.64	GO:0007059	chromosome segregation
0.61	GO:0031163	metallo-sulfur cluster assembly
0.55	GO:0006790	sulfur compound metabolic process
0.53	GO:0051188	cofactor biosynthetic process
0.38	GO:0001510	RNA methylation
0.35	GO:0006508	proteolysis

0.37	GO:0008168	methyltransferase activity
0.36	GO:0004252	serine-type endopeptidase activity

0.80	GO:0097361	CIA complex
0.79	GO:0071817	MMXD complex
0.62	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.37

GO:0008168

tr|T1G178|T1G178_HELRO
Uncharacterized protein
Search

0.25	E3 ubiquitin-protein ligase

0.47	GO:0001967	suckling behavior
0.46	GO:0042048	olfactory behavior
0.44	GO:0001701	in utero embryonic development
0.44	GO:0016567	protein ubiquitination
0.44	GO:0006511	ubiquitin-dependent protein catabolic process
0.43	GO:0007608	sensory perception of smell
0.41	GO:0010498	proteasomal protein catabolic process
0.36	GO:0034126	positive regulation of MyD88-dependent toll-like receptor signaling pathway
0.36	GO:0045880	positive regulation of smoothened signaling pathway
0.35	GO:0043066	negative regulation of apoptotic process

0.63	GO:0008270	zinc ion binding
0.55	GO:0016874	ligase activity
0.46	GO:0061630	ubiquitin protein ligase activity
0.33	GO:0005515	protein binding
0.32	GO:0003723	RNA binding

0.41	GO:0000151	ubiquitin ligase complex
0.35	GO:0005737	cytoplasm
0.32	GO:0005634	nucleus
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016020	membrane

0.55

GO:0016874

tr|T1G179|T1G179_HELRO
Uncharacterized protein
Search

0.59	GO:0007155	cell adhesion
0.53	GO:0007399	nervous system development
0.50	GO:0060060	post-embryonic retina morphogenesis in camera-type eye
0.48	GO:0030154	cell differentiation
0.47	GO:0007626	locomotory behavior
0.47	GO:0060284	regulation of cell development
0.47	GO:0006468	protein phosphorylation
0.47	GO:0040017	positive regulation of locomotion
0.47	GO:0061387	regulation of extent of cell growth
0.47	GO:0051239	regulation of multicellular organismal process

0.47	GO:0004672	protein kinase activity
0.43	GO:0097493	structural molecule activity conferring elasticity
0.43	GO:0051371	muscle alpha-actinin binding
0.43	GO:0030554	adenyl nucleotide binding
0.43	GO:0008307	structural constituent of muscle
0.42	GO:0097367	carbohydrate derivative binding
0.42	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0008144	drug binding
0.41	GO:0051015	actin filament binding
0.40	GO:0019899	enzyme binding

0.48	GO:0005887	integral component of plasma membrane
0.47	GO:0030424	axon
0.47	GO:0030426	growth cone
0.45	GO:0031672	A band
0.43	GO:0005859	muscle myosin complex
0.42	GO:0030018	Z disc
0.39	GO:0030054	cell junction
0.38	GO:0045202	synapse
0.37	GO:0005865	striated muscle thin filament
0.37	GO:0000794	condensed nuclear chromosome

0.36	EC:1.11.1.7	GO:0004601
0.36	KEGG:R03532	GO:0004601

tr|T1G180|T1G180_HELRO
Uncharacterized protein
Search

0.11	probable palmitoyltransferase ZDHHC1

0.59

GO:0018345

protein palmitoylation

0.79	GO:0019706	protein-cysteine S-palmitoyltransferase activity
0.33	GO:0003677	DNA binding

0.50	GO:0005783	endoplasmic reticulum
0.38	GO:0070062	extracellular exosome
0.30	GO:0044425	membrane part

0.79

GO:0019706

tr|T1G181|T1G181_HELRO
Uncharacterized protein
Search

0.49	GO:0030513	positive regulation of BMP signaling pathway
0.47	GO:0007219	Notch signaling pathway
0.44	GO:0045893	positive regulation of transcription, DNA-templated
0.43	GO:0045892	negative regulation of transcription, DNA-templated
0.35	GO:0007399	nervous system development
0.34	GO:0030154	cell differentiation
0.33	GO:0006351	transcription, DNA-templated

0.51	GO:0003676	nucleic acid binding
0.35	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding

0.43	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1G182|T1G182_HELRO
Uncharacterized protein
Search

0.78	Paired box protein Pax-9

0.70	GO:0007275	multicellular organism development
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.40	GO:1902680	positive regulation of RNA biosynthetic process
0.35	GO:0030154	cell differentiation
0.34	GO:0009653	anatomical structure morphogenesis
0.33	GO:0006030	chitin metabolic process

0.56	GO:0043565	sequence-specific DNA binding
0.42	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.42	GO:0001012	RNA polymerase II regulatory region DNA binding
0.42	GO:0008270	zinc ion binding
0.41	GO:0003690	double-stranded DNA binding
0.33	GO:0008061	chitin binding

0.61	GO:0005634	nucleus
0.33	GO:0005576	extracellular region
0.30	GO:0016020	membrane

tr|T1G183|T1G183_HELRO
Uncharacterized protein
Search

0.79	Transcription factor SOX-14

0.51	GO:2001141	regulation of RNA biosynthetic process
0.51	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.50	GO:0010468	regulation of gene expression
0.44	GO:0007417	central nervous system development
0.42	GO:0043049	otic placode formation
0.42	GO:0048699	generation of neurons
0.41	GO:0007422	peripheral nervous system development
0.40	GO:0060322	head development
0.39	GO:0061386	closure of optic fissure
0.39	GO:0044093	positive regulation of molecular function

0.55	GO:0003677	DNA binding
0.44	GO:0140110	transcription regulator activity
0.36	GO:0008013	beta-catenin binding
0.35	GO:0001067	regulatory region nucleic acid binding
0.34	GO:0008135	translation factor activity, RNA binding
0.33	GO:0005516	calmodulin binding
0.32	GO:0005198	structural molecule activity

0.61	GO:0005634	nucleus
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part
0.33	GO:0005923	bicellular tight junction
0.33	GO:0005737	cytoplasm
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1G184|T1G184_HELRO
rRNA adenine N(6)-methyltransferase
Search

DIMT1

0.63	rRNA adenine N(6)-methyltransferase

0.72	GO:0031167	rRNA methylation
0.53	GO:2000234	positive regulation of rRNA processing
0.33	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic

0.78	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity
0.59	GO:0003723	RNA binding
0.41	GO:0052909	18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity
0.34	GO:0004523	RNA-DNA hybrid ribonuclease activity

0.47	GO:0005730	nucleolus
0.44	GO:0005829	cytosol
0.44	GO:0005759	mitochondrial matrix
0.36	GO:0005654	nucleoplasm

0.78

GO:0000179

tr|T1G185|T1G185_HELRO
Uncharacterized protein
Search

0.18	Transposase

0.34	GO:0015074	DNA integration
0.34	GO:0010951	negative regulation of endopeptidase activity
0.34	GO:0007165	signal transduction
0.33	GO:0051607	defense response to virus
0.32	GO:0006310	DNA recombination

0.51	GO:0003676	nucleic acid binding
0.35	GO:0046872	metal ion binding
0.34	GO:0004867	serine-type endopeptidase inhibitor activity
0.32	GO:0004871	signal transducer activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.32	GO:0005622	intracellular
0.32	GO:0043227	membrane-bounded organelle
0.30	GO:0016020	membrane

tr|T1G186|T1G186_HELRO
Uncharacterized protein
Search

EPB41L4B

0.77	Erythrocyte membrane protein band 4.1 like 4B

0.50	GO:0051549	positive regulation of keratinocyte migration
0.49	GO:0046665	amnioserosa maintenance
0.48	GO:0031032	actomyosin structure organization
0.48	GO:0007390	germ-band shortening
0.47	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity
0.47	GO:0008258	head involution
0.47	GO:0030859	polarized epithelial cell differentiation
0.47	GO:0035089	establishment of apical/basal cell polarity
0.47	GO:0007391	dorsal closure
0.46	GO:0090162	establishment of epithelial cell polarity

0.67	GO:0008092	cytoskeletal protein binding
0.41	GO:0005200	structural constituent of cytoskeleton

0.69	GO:0005856	cytoskeleton
0.49	GO:0005912	adherens junction
0.47	GO:0005918	septate junction
0.46	GO:0045177	apical part of cell
0.45	GO:0016323	basolateral plasma membrane
0.42	GO:0005829	cytosol
0.38	GO:0005923	bicellular tight junction
0.33	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

tr|T1G187|T1G187_HELRO
Uncharacterized protein
Search

0.47	L-threonine dehydratase catabolic TdcB

0.71

GO:0006567

threonine catabolic process

0.72	GO:0004794	L-threonine ammonia-lyase activity
0.33	GO:0030170	pyridoxal phosphate binding

0.30

GO:0031224

intrinsic component of membrane

0.72

EC:4.3.1.19

GO:0004794

tr|T1G188|T1G188_HELRO
Uncharacterized protein
Search

tr|T1G189|T1G189_HELRO
Uncharacterized protein
Search

0.51

GO:0006508

proteolysis

0.59

GO:0008234

cysteine-type peptidase activity

0.30

GO:0044425

membrane part

0.59

GO:0008234

tr|T1G190|T1G190_HELRO
Uncharacterized protein
Search

0.84	Potassium inwardly rectifying channel DIR

0.78	GO:0034765	regulation of ion transmembrane transport
0.71	GO:0006813	potassium ion transport
0.61	GO:0098655	cation transmembrane transport
0.45	GO:0045475	locomotor rhythm
0.44	GO:0035220	wing disc development
0.43	GO:0042391	regulation of membrane potential
0.36	GO:0098660	inorganic ion transmembrane transport
0.34	GO:0046662	regulation of oviposition
0.34	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.34	GO:0006836	neurotransmitter transport

0.84	GO:0005242	inward rectifier potassium channel activity
0.34	GO:0005328	neurotransmitter:sodium symporter activity
0.32	GO:0008270	zinc ion binding
0.32	GO:0003676	nucleic acid binding

0.37	GO:0005887	integral component of plasma membrane
0.34	GO:0043025	neuronal cell body
0.34	GO:0043005	neuron projection

tr|T1G191|T1G191_HELRO
Uncharacterized protein
Search

0.66	Suppressor of lurcher protein 1

0.41	GO:0055114	oxidation-reduction process
0.41	GO:0050830	defense response to Gram-positive bacterium
0.38	GO:0006898	receptor-mediated endocytosis
0.36	GO:0006508	proteolysis

0.51	GO:0004471	malate dehydrogenase (decarboxylating) (NAD+) activity
0.47	GO:0005509	calcium ion binding
0.46	GO:0051287	NAD binding
0.40	GO:0005044	scavenger receptor activity
0.37	GO:0004252	serine-type endopeptidase activity

0.30

GO:0031224

intrinsic component of membrane

0.51	EC:1.1.1.38 EC:1.1.1.39	GO:0004471
0.51	KEGG:R00214	GO:0004471

tr|T1G192|T1G192_HELRO
Histone acetyltransferase
Search

0.36	Histone acetyltransferase

0.78	GO:0016573	histone acetylation
0.65	GO:0006334	nucleosome assembly
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.47	GO:2000873	regulation of histone H4 acetylation involved in response to DNA damage stimulus
0.46	GO:0048518	positive regulation of biological process
0.46	GO:1990823	response to leukemia inhibitory factor
0.45	GO:0048523	negative regulation of cellular process
0.45	GO:0030330	DNA damage response, signal transduction by p53 class mediator

0.80	GO:0004402	histone acetyltransferase activity
0.50	GO:0046872	metal ion binding
0.48	GO:0003677	DNA binding
0.43	GO:0003713	transcription coactivator activity
0.43	GO:0008134	transcription factor binding
0.42	GO:0003682	chromatin binding
0.35	GO:0032403	protein complex binding
0.33	GO:0009982	pseudouridine synthase activity
0.33	GO:0003700	DNA binding transcription factor activity
0.32	GO:0008168	methyltransferase activity

0.62	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.53	GO:0031248	protein acetyltransferase complex
0.49	GO:0070013	intracellular organelle lumen
0.46	GO:0005705	polytene chromosome interband
0.46	GO:0000805	X chromosome
0.42	GO:0005667	transcription factor complex
0.38	GO:0030529	intracellular ribonucleoprotein complex
0.37	GO:0034507	chromosome, centromeric outer repeat region
0.33	GO:0005829	cytosol

0.80

GO:0004402

tr|T1G193|T1G193_HELRO
Uncharacterized protein
Search

MINDY2

0.96	Ubiquitin carboxyl-terminal hydrolase MINDY-2

0.85

GO:0071108

protein K48-linked deubiquitination

0.85	GO:1990380	Lys48-specific deubiquitinase activity
0.80	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.61	GO:0070004	cysteine-type exopeptidase activity
0.60	GO:0036435	K48-linked polyubiquitin modification-dependent protein binding
0.53	GO:0071795	K11-linked polyubiquitin modification-dependent protein binding
0.53	GO:0071796	K6-linked polyubiquitin modification-dependent protein binding
0.51	GO:0004180	carboxypeptidase activity
0.50	GO:0070530	K63-linked polyubiquitin modification-dependent protein binding

0.50	GO:0005654	nucleoplasm
0.35	GO:0070062	extracellular exosome

tr|T1G194|T1G194_HELRO
Calcium-transporting ATPase
Search

0.58	Calcium-transporting ATPase

0.77	GO:0070588	calcium ion transmembrane transport
0.69	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.43	GO:0006874	cellular calcium ion homeostasis

0.81	GO:0005388	calcium-transporting ATPase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.35	GO:0005886	plasma membrane
0.32	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.81

EC:3.6.3.8

GO:0005388

tr|T1G195|T1G195_HELRO
Uncharacterized protein
Search

ATL2

0.58	Atlastin GTPase 2

0.52	GO:1990809	endoplasmic reticulum tubular network membrane organization
0.49	GO:0007030	Golgi organization
0.47	GO:0051260	protein homooligomerization
0.35	GO:0006888	ER to Golgi vesicle-mediated transport

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0042802	identical protein binding

0.52	GO:0098826	endoplasmic reticulum tubular network membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1G197|T1G197_HELRO
Uncharacterized protein
Search

0.10	Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 (Fragment)

0.71	GO:0043547	positive regulation of GTPase activity
0.47	GO:0007165	signal transduction
0.43	GO:0072375	medium-term memory
0.42	GO:0033601	positive regulation of mammary gland epithelial cell proliferation
0.42	GO:0060749	mammary gland alveolus development
0.41	GO:0046427	positive regulation of JAK-STAT cascade
0.40	GO:0043066	negative regulation of apoptotic process
0.39	GO:0045944	positive regulation of transcription by RNA polymerase II
0.35	GO:1901099	negative regulation of signal transduction in absence of ligand
0.35	GO:2001239	regulation of extrinsic apoptotic signaling pathway in absence of ligand

0.72	GO:0005096	GTPase activator activity
0.67	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0046872	metal ion binding
0.39	GO:0005543	phospholipid binding
0.34	GO:0030295	protein kinase activator activity
0.34	GO:0019901	protein kinase binding

0.39	GO:0005730	nucleolus
0.36	GO:0005739	mitochondrion
0.33	GO:0031982	vesicle
0.33	GO:0005829	cytosol
0.33	GO:0043230	extracellular organelle
0.33	GO:0005615	extracellular space
0.32	GO:0012505	endomembrane system
0.30	GO:0016020	membrane

tr|T1G198|T1G198_HELRO
Uncharacterized protein
Search

SLC12A9

0.38	Cation chloride cotransporter

0.59	GO:0006811	ion transport
0.55	GO:0055085	transmembrane transport
0.34	GO:0043413	macromolecule glycosylation
0.33	GO:0009101	glycoprotein biosynthetic process
0.33	GO:0006886	intracellular protein transport
0.33	GO:0016192	vesicle-mediated transport
0.33	GO:0006464	cellular protein modification process
0.32	GO:0006351	transcription, DNA-templated
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.56	GO:0005215	transporter activity
0.33	GO:0030246	carbohydrate binding
0.33	GO:0016757	transferase activity, transferring glycosyl groups
0.33	GO:0005198	structural molecule activity
0.33	GO:0003700	DNA binding transcription factor activity
0.32	GO:0003677	DNA binding
0.32	GO:0016491	oxidoreductase activity
0.32	GO:1901265	nucleoside phosphate binding
0.32	GO:0036094	small molecule binding

0.35	GO:0005794	Golgi apparatus
0.34	GO:0030663	COPI-coated vesicle membrane
0.34	GO:0030120	vesicle coat
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.33

GO:0016757

tr|T1G1A0|T1G1A0_HELRO
Uncharacterized protein
Search

0.37	molybdate-anion transporter

0.77	GO:0015689	molybdate ion transport
0.39	GO:0006352	DNA-templated transcription, initiation
0.33	GO:0006886	intracellular protein transport
0.33	GO:0016192	vesicle-mediated transport
0.32	GO:0007186	G-protein coupled receptor signaling pathway

0.79	GO:0015098	molybdate ion transmembrane transporter activity
0.41	GO:0046982	protein heterodimerization activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0004930	G-protein coupled receptor activity
0.31	GO:0003723	RNA binding

0.42	GO:0005669	transcription factor TFIID complex
0.37	GO:0005794	Golgi apparatus
0.36	GO:0005768	endosome
0.36	GO:0005774	vacuolar membrane
0.35	GO:0031984	organelle subcompartment
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1G1A1|T1G1A1_HELRO
Uncharacterized protein
Search

0.54	Double-strand-break repair protein rad21

0.46	GO:0007062	sister chromatid cohesion
0.45	GO:0016322	neuron remodeling
0.44	GO:0000070	mitotic sister chromatid segregation
0.44	GO:0070193	synaptonemal complex organization
0.42	GO:0010604	positive regulation of macromolecule metabolic process
0.41	GO:0003187	ventriculo bulbo valve morphogenesis
0.39	GO:0003181	atrioventricular valve morphogenesis
0.39	GO:0060037	pharyngeal system development
0.39	GO:0048484	enteric nervous system development
0.39	GO:0006302	double-strand break repair

0.41	GO:0003682	chromatin binding
0.37	GO:0003924	GTPase activity
0.37	GO:0005525	GTP binding
0.36	GO:0043565	sequence-specific DNA binding
0.34	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.33	GO:0032403	protein complex binding
0.33	GO:0003735	structural constituent of ribosome

0.69	GO:0000228	nuclear chromosome
0.47	GO:0008278	cohesin complex
0.45	GO:0005705	polytene chromosome interband
0.44	GO:0005721	pericentric heterochromatin
0.34	GO:0016363	nuclear matrix
0.33	GO:0005654	nucleoplasm
0.33	GO:0005840	ribosome
0.30	GO:0016020	membrane

tr|T1G1A2|T1G1A2_HELRO
Uncharacterized protein
Search

IMP3

0.81	U3 small nucleolar ribonucleoprotein protein IMP3

0.46	GO:0045903	positive regulation of translational fidelity
0.42	GO:0006364	rRNA processing
0.36	GO:0042274	ribosomal small subunit biogenesis
0.34	GO:0035335	peptidyl-tyrosine dephosphorylation
0.33	GO:0007165	signal transduction
0.33	GO:0034220	ion transmembrane transport
0.33	GO:0006508	proteolysis
0.32	GO:0006468	protein phosphorylation

0.66	GO:0019843	rRNA binding
0.46	GO:0030515	snoRNA binding
0.40	GO:0003735	structural constituent of ribosome
0.36	GO:0030519	snoRNP binding
0.34	GO:0005230	extracellular ligand-gated ion channel activity
0.34	GO:0004725	protein tyrosine phosphatase activity
0.34	GO:0004181	metallocarboxypeptidase activity
0.34	GO:0004888	transmembrane signaling receptor activity
0.33	GO:0004674	protein serine/threonine kinase activity
0.33	GO:0008270	zinc ion binding

0.56	GO:0019013	viral nucleocapsid
0.52	GO:0030529	intracellular ribonucleoprotein complex
0.45	GO:0044452	nucleolar part
0.39	GO:0043234	protein complex
0.39	GO:0044444	cytoplasmic part
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.34

GO:0004725

tr|T1G1A3|T1G1A3_HELRO
Uncharacterized protein
Search

FAM213A

0.92	Selenoprotein U

0.60	GO:0045670	regulation of osteoclast differentiation
0.54	GO:0098869	cellular oxidant detoxification
0.52	GO:0055114	oxidation-reduction process

0.54

GO:0016209

antioxidant activity

0.41	GO:0005737	cytoplasm
0.36	GO:0005576	extracellular region
0.35	GO:0043227	membrane-bounded organelle
0.34	GO:0043229	intracellular organelle
0.30	GO:0044425	membrane part

tr|T1G1A4|T1G1A4_HELRO
Protein kish
Search

0.44	GO:0009306	protein secretion
0.43	GO:0046907	intracellular transport
0.33	GO:0043043	peptide biosynthetic process
0.33	GO:0010467	gene expression
0.33	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.33	GO:0044267	cellular protein metabolic process
0.33	GO:0009059	macromolecule biosynthetic process
0.33	GO:0006399	tRNA metabolic process

0.34	GO:0003735	structural constituent of ribosome
0.34	GO:0004526	ribonuclease P activity
0.32	GO:0003676	nucleic acid binding

0.55	GO:0000139	Golgi membrane
0.33	GO:0005840	ribosome
0.33	GO:0005739	mitochondrion
0.32	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.34

EC:3.1.26.5

GO:0004526

tr|T1G1A5|T1G1A5_HELRO
Uncharacterized protein
Search

0.61	AAR2 splicing factor homolog (S. cerevisiae)

0.85

GO:0000244

spliceosomal tri-snRNP complex assembly

tr|T1G1A6|T1G1A6_HELRO
Uncharacterized protein
Search

0.37	Carbonate dehydratase, eukaryotic-type

0.65	GO:0006730	one-carbon metabolic process
0.46	GO:0032849	positive regulation of cellular pH reduction
0.46	GO:2001225	regulation of chloride transport
0.45	GO:0032230	positive regulation of synaptic transmission, GABAergic
0.43	GO:0036269	swimming behavior
0.36	GO:0010037	response to carbon dioxide
0.36	GO:0006470	protein dephosphorylation

0.71	GO:0004089	carbonate dehydratase activity
0.57	GO:0008270	zinc ion binding
0.36	GO:0004722	protein serine/threonine phosphatase activity

0.40	GO:0005829	cytosol
0.38	GO:0046658	anchored component of plasma membrane
0.30	GO:0016021	integral component of membrane

0.71

GO:0004089

tr|T1G1A7|T1G1A7_HELRO
Uncharacterized protein
Search

0.66	Phosphatase 1K, mitochondrial

0.72	GO:0006470	protein dephosphorylation
0.42	GO:0031016	pancreas development
0.42	GO:0001889	liver development
0.42	GO:0048565	digestive tract development
0.41	GO:0007507	heart development
0.41	GO:0007420	brain development
0.41	GO:0043066	negative regulation of apoptotic process
0.35	GO:0061191	positive regulation of vacuole fusion, non-autophagic
0.34	GO:1901098	positive regulation of autophagosome maturation
0.34	GO:1903715	regulation of aerobic respiration

0.77	GO:0004722	protein serine/threonine phosphatase activity
0.52	GO:0046872	metal ion binding
0.33	GO:0004411	homogentisate 1,2-dioxygenase activity
0.33	GO:0004672	protein kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032553	ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.34	GO:0000329	fungal-type vacuole membrane
0.33	GO:0005759	mitochondrial matrix
0.32	GO:0031966	mitochondrial membrane
0.32	GO:0019866	organelle inner membrane
0.32	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.33	EC:1.13.11.5	GO:0004411
0.33	KEGG:R02519	GO:0004411

tr|T1G1A8|T1G1A8_HELRO
Uncharacterized protein
Search

0.82	Disks large homolog 2 isoform 3

0.72	GO:0010923	negative regulation of phosphatase activity
0.71	GO:0019233	sensory perception of pain
0.71	GO:0007268	chemical synaptic transmission
0.70	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity
0.68	GO:0097120	receptor localization to synapse
0.67	GO:0043113	receptor clustering
0.67	GO:0046710	GDP metabolic process
0.64	GO:0046037	GMP metabolic process
0.59	GO:0007399	nervous system development
0.50	GO:0043297	apical junction assembly

0.69	GO:0035255	ionotropic glutamate receptor binding
0.69	GO:0019900	kinase binding
0.67	GO:0004385	guanylate kinase activity
0.53	GO:0019902	phosphatase binding
0.47	GO:0031625	ubiquitin protein ligase binding
0.45	GO:0008022	protein C-terminus binding
0.43	GO:0019904	protein domain specific binding
0.41	GO:0015459	potassium channel regulator activity
0.40	GO:0044325	ion channel binding
0.40	GO:0046982	protein heterodimerization activity

0.76	GO:0014069	postsynaptic density
0.74	GO:0044224	juxtaparanode region of axon
0.73	GO:0045211	postsynaptic membrane
0.69	GO:0008328	ionotropic glutamate receptor complex
0.69	GO:0030054	cell junction
0.64	GO:0016323	basolateral plasma membrane
0.52	GO:0034703	cation channel complex
0.43	GO:0016328	lateral plasma membrane
0.42	GO:0043219	lateral loop
0.41	GO:0035748	myelin sheath abaxonal region

0.67

GO:0004385

tr|T1G1A9|T1G1A9_HELRO
Uncharacterized protein
Search

tr|T1G1B0|T1G1B0_HELRO
Glucose-6-phosphate 1-dehydrogenase
Search

G6PD

0.43	Glucose-6-phosphate 1-dehydrogenase X

0.72	GO:0006098	pentose-phosphate shunt
0.71	GO:0006006	glucose metabolic process
0.53	GO:0055114	oxidation-reduction process
0.52	GO:0019322	pentose biosynthetic process
0.51	GO:0010732	regulation of protein glutathionylation
0.50	GO:0043249	erythrocyte maturation
0.48	GO:0006695	cholesterol biosynthetic process
0.45	GO:0006749	glutathione metabolic process
0.45	GO:0034599	cellular response to oxidative stress
0.45	GO:0031400	negative regulation of protein modification process

0.79	GO:0004345	glucose-6-phosphate dehydrogenase activity
0.70	GO:0050661	NADP binding
0.47	GO:0005536	glucose binding
0.45	GO:0042803	protein homodimerization activity
0.33	GO:0004527	exonuclease activity

0.45	GO:0009898	cytoplasmic side of plasma membrane
0.43	GO:0005829	cytosol
0.37	GO:0070062	extracellular exosome
0.34	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.79

EC:1.1.1.49

GO:0004345

tr|T1G1B1|T1G1B1_HELRO
RuvB-like helicase
Search

RUVBL2

0.65	RuvB-like helicase

0.70	GO:0032508	DNA duplex unwinding
0.60	GO:0006281	DNA repair
0.57	GO:0016569	covalent chromatin modification
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0006310	DNA recombination
0.56	GO:0010468	regulation of gene expression
0.52	GO:0071899	negative regulation of estrogen receptor binding
0.52	GO:0000492	box C/D snoRNP assembly

0.81	GO:0043141	ATP-dependent 5'-3' DNA helicase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.51	GO:0001094	TFIID-class transcription factor binding
0.50	GO:0051117	ATPase binding
0.50	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding
0.50	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.49	GO:0031490	chromatin DNA binding

0.83	GO:0097255	R2TP complex
0.80	GO:0035267	NuA4 histone acetyltransferase complex
0.80	GO:0031011	Ino80 complex
0.54	GO:0000812	Swr1 complex
0.49	GO:0005719	nuclear euchromatin
0.49	GO:0071339	MLL1 complex
0.46	GO:0005813	centrosome
0.43	GO:0005829	cytosol
0.41	GO:0030529	intracellular ribonucleoprotein complex
0.39	GO:0070209	ASTRA complex

0.81

EC:3.6.1

GO:0043141

tr|T1G1B2|T1G1B2_HELRO
Uncharacterized protein
Search

PDXH

0.41	Pyridoxamine-phosphate oxidase

0.77	GO:0008615	pyridoxine biosynthetic process
0.77	GO:0042823	pyridoxal phosphate biosynthetic process
0.52	GO:0055114	oxidation-reduction process
0.43	GO:0009744	response to sucrose
0.42	GO:0006734	NADH metabolic process
0.39	GO:0006739	NADP metabolic process

0.81	GO:0004733	pyridoxamine-phosphate oxidase activity
0.70	GO:0010181	FMN binding
0.44	GO:0052856	NADHX epimerase activity
0.43	GO:0052857	NADPHX epimerase activity
0.37	GO:0046872	metal ion binding

0.38	GO:0005829	cytosol
0.37	GO:0009507	chloroplast
0.36	GO:0005739	mitochondrion

0.81

EC:1.4.3.5

GO:0004733

tr|T1G1B3|T1G1B3_HELRO
Uncharacterized protein
Search

0.40	Phosphodiesterase

0.61	GO:0007165	signal transduction
0.36	GO:0046068	cGMP metabolic process
0.35	GO:0007610	behavior
0.35	GO:0010754	negative regulation of cGMP-mediated signaling
0.35	GO:0090038	negative regulation of protein kinase C signaling
0.35	GO:0032528	microvillus organization
0.35	GO:0010446	response to alkaline pH
0.34	GO:0009214	cyclic nucleotide catabolic process
0.34	GO:0008340	determination of adult lifespan
0.34	GO:0042542	response to hydrogen peroxide

0.80	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.54	GO:0046872	metal ion binding
0.35	GO:0005516	calmodulin binding

0.33	GO:0005615	extracellular space
0.30	GO:0016020	membrane

0.80

GO:0004114

tr|T1G1B4|T1G1B4_HELRO
Uncharacterized protein
Search

0.67	Transcription initiation factor IIE subunit beta

0.79	GO:0006367	transcription initiation from RNA polymerase II promoter
0.60	GO:0006413	translational initiation
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression

0.61	GO:0003743	translation initiation factor activity
0.55	GO:0003677	DNA binding

0.85

GO:0005673

transcription factor TFIIE complex

tr|T1G1B5|T1G1B5_HELRO
Uncharacterized protein
Search

tr|T1G1B6|T1G1B6_HELRO
Uncharacterized protein
Search

0.38	NADH dehydrogenase 1 alpha subcomplex subunit 6

0.56	GO:0006979	response to oxidative stress
0.50	GO:0055114	oxidation-reduction process
0.36	GO:0032981	mitochondrial respiratory chain complex I assembly
0.36	GO:0006119	oxidative phosphorylation
0.34	GO:0065009	regulation of molecular function

0.38	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.35	GO:0005085	guanyl-nucleotide exchange factor activity

0.61	GO:0070469	respiratory chain
0.60	GO:0031966	mitochondrial membrane
0.60	GO:0019866	organelle inner membrane
0.60	GO:0030964	NADH dehydrogenase complex
0.56	GO:0098798	mitochondrial protein complex
0.53	GO:1990204	oxidoreductase complex
0.49	GO:0098796	membrane protein complex
0.30	GO:0031224	intrinsic component of membrane

0.38

GO:0008137

tr|T1G1B7|T1G1B7_HELRO
Uncharacterized protein
Search

0.64	Myocyte-specific enhancer factor 2A

0.74	GO:0045944	positive regulation of transcription by RNA polymerase II
0.58	GO:0006351	transcription, DNA-templated
0.49	GO:0060914	heart formation
0.48	GO:0055007	cardiac muscle cell differentiation
0.47	GO:0003143	embryonic heart tube morphogenesis
0.46	GO:0003185	sinoatrial valve morphogenesis
0.46	GO:0071374	cellular response to parathyroid hormone stimulus
0.46	GO:2001016	positive regulation of skeletal muscle cell differentiation
0.46	GO:2000987	positive regulation of behavioral fear response
0.46	GO:2000111	positive regulation of macrophage apoptotic process

0.77	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.68	GO:0046983	protein dimerization activity
0.45	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding
0.44	GO:0003680	AT DNA binding
0.44	GO:0033613	activating transcription factor binding
0.44	GO:0071837	HMG box domain binding
0.44	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.43	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding
0.42	GO:0001158	enhancer sequence-specific DNA binding
0.42	GO:0042826	histone deacetylase binding

0.61	GO:0005634	nucleus
0.41	GO:0070013	intracellular organelle lumen
0.41	GO:0098794	postsynapse
0.38	GO:0044446	intracellular organelle part
0.38	GO:0043234	protein complex
0.38	GO:0016528	sarcoplasm
0.33	GO:0030017	sarcomere
0.33	GO:0005794	Golgi apparatus
0.33	GO:0098588	bounding membrane of organelle
0.30	GO:0016021	integral component of membrane

0.34

GO:0008376

tr|T1G1B8|T1G1B8_HELRO
Uncharacterized protein
Search

EMC2

0.44	ER membrane protein complex subunit 2-B

0.70

GO:0034975

protein folding in endoplasmic reticulum

0.36

GO:0005515

protein binding

0.82	GO:0072546	ER membrane protein complex
0.55	GO:0005739	mitochondrion
0.45	GO:0005634	nucleus

tr|T1G1B9|T1G1B9_HELRO
60S ribosome subunit biogenesis protein NIP7 homolog
Search

NIP7

0.81	60S ribosome subunit biogenesis protein NIP7 homolog

0.74	GO:0042255	ribosome assembly
0.44	GO:0042273	ribosomal large subunit biogenesis

0.58

GO:0003723

RNA binding

0.60	GO:0005634	nucleus
0.45	GO:0030687	preribosome, large subunit precursor
0.43	GO:0031974	membrane-enclosed lumen
0.41	GO:0043232	intracellular non-membrane-bounded organelle
0.40	GO:0044446	intracellular organelle part
0.40	GO:0005829	cytosol

tr|T1G1C0|T1G1C0_HELRO
Uncharacterized protein
Search

0.67	GO:0043547	positive regulation of GTPase activity
0.47	GO:0007165	signal transduction
0.36	GO:0072375	medium-term memory
0.36	GO:0000060	protein import into nucleus, translocation
0.35	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.35	GO:0034614	cellular response to reactive oxygen species

0.68	GO:0005096	GTPase activator activity
0.65	GO:0003924	GTPase activity
0.63	GO:0032550	purine ribonucleoside binding
0.63	GO:0019001	guanyl nucleotide binding
0.52	GO:0032555	purine ribonucleotide binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0046872	metal ion binding
0.37	GO:0005543	phospholipid binding
0.36	GO:0031593	polyubiquitin modification-dependent protein binding

0.33	GO:0005737	cytoplasm
0.33	GO:0005634	nucleus
0.33	GO:0071944	cell periphery
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016020	membrane

tr|T1G1C1|T1G1C1_HELRO
Lipase maturation factor
Search

LMF1

0.78	Lipase maturation factor

0.55	GO:0071830	triglyceride-rich lipoprotein particle clearance
0.54	GO:0051006	positive regulation of lipoprotein lipase activity
0.54	GO:0033578	protein glycosylation in Golgi
0.53	GO:0090181	regulation of cholesterol metabolic process
0.52	GO:0090207	regulation of triglyceride metabolic process
0.50	GO:0006641	triglyceride metabolic process
0.50	GO:0051604	protein maturation
0.49	GO:0006888	ER to Golgi vesicle-mediated transport
0.46	GO:0009306	protein secretion

0.33

GO:0005515

protein binding

0.70	GO:0005789	endoplasmic reticulum membrane
0.46	GO:0005794	Golgi apparatus
0.30	GO:0016021	integral component of membrane

tr|T1G1C2|T1G1C2_HELRO
Ribonuclease
Search

RNASEH2A

0.55	Ribonuclease

0.70	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.50	GO:0006298	mismatch repair
0.50	GO:0043137	DNA replication, removal of RNA primer
0.41	GO:0045005	DNA-dependent DNA replication maintenance of fidelity
0.34	GO:0007010	cytoskeleton organization
0.34	GO:0006468	protein phosphorylation
0.34	GO:0035556	intracellular signal transduction
0.33	GO:0006265	DNA topological change

0.74	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.59	GO:0003723	RNA binding
0.34	GO:0004674	protein serine/threonine kinase activity
0.34	GO:0000287	magnesium ion binding
0.33	GO:0003917	DNA topoisomerase type I activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003677	DNA binding

0.55	GO:0032299	ribonuclease H2 complex
0.43	GO:0005654	nucleoplasm
0.42	GO:0005829	cytosol

0.74

EC:3.1.26.4

GO:0004523

tr|T1G1C3|T1G1C3_HELRO
Adenylate kinase
Search

ADK2

0.46	Adenylate kinase

0.81	GO:0006172	ADP biosynthetic process
0.69	GO:0046939	nucleotide phosphorylation
0.68	GO:0046033	AMP metabolic process
0.57	GO:0046034	ATP metabolic process
0.36	GO:0090038	negative regulation of protein kinase C signaling
0.35	GO:0035172	hemocyte proliferation
0.35	GO:2000114	regulation of establishment of cell polarity
0.35	GO:0046060	dATP metabolic process
0.35	GO:0048513	animal organ development
0.35	GO:0097066	response to thyroid hormone

0.78	GO:0004017	adenylate kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.75	GO:0005758	mitochondrial intermembrane space
0.62	GO:0005829	cytosol
0.44	GO:0097226	sperm mitochondrial sheath
0.37	GO:0031966	mitochondrial membrane
0.37	GO:0019866	organelle inner membrane
0.34	GO:0070062	extracellular exosome
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.78

EC:2.7.4.3

GO:0004017

tr|T1G1C4|T1G1C4_HELRO
Uncharacterized protein
Search

GAD1

0.44	Glutamic acid decarboxylase

0.57	GO:0019752	carboxylic acid metabolic process
0.46	GO:0042412	taurine biosynthetic process
0.41	GO:0051932	synaptic transmission, GABAergic
0.35	GO:0042136	neurotransmitter biosynthetic process
0.33	GO:0044273	sulfur compound catabolic process
0.33	GO:0016054	organic acid catabolic process
0.33	GO:1901565	organonitrogen compound catabolic process
0.30	GO:0044238	primary metabolic process

0.68	GO:0016831	carboxy-lyase activity
0.67	GO:0030170	pyridoxal phosphate binding

0.40	GO:0060077	inhibitory synapse
0.39	GO:0043204	perikaryon
0.39	GO:0008021	synaptic vesicle
0.39	GO:0030424	axon
0.33	GO:0005829	cytosol

0.68

EC:4.1.1

GO:0016831

tr|T1G1C5|T1G1C5_HELRO
Uncharacterized protein
Search

tr|T1G1C6|T1G1C6_HELRO
Uncharacterized protein
Search

0.64	KIAA0999 protein (Predicted) (Fragment)

0.63

GO:0006468

protein phosphorylation

0.64	GO:0004672	protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

tr|T1G1C7|T1G1C7_HELRO
Uncharacterized protein
Search

tr|T1G1C8|T1G1C8_HELRO
Uncharacterized protein
Search

0.58	LIM class homeodomain transcription factor, apterous subclass

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.42	GO:0007481	haltere disc morphogenesis
0.42	GO:0002164	larval development
0.41	GO:0007479	leg disc proximal/distal pattern formation
0.41	GO:0007482	haltere development
0.41	GO:0007409	axonogenesis
0.41	GO:0036011	imaginal disc-derived leg segmentation
0.40	GO:0048190	wing disc dorsal/ventral pattern formation

0.64	GO:0043565	sequence-specific DNA binding
0.51	GO:0046872	metal ion binding
0.40	GO:0001012	RNA polymerase II regulatory region DNA binding
0.39	GO:0003690	double-stranded DNA binding
0.33	GO:0004725	protein tyrosine phosphatase activity
0.32	GO:0016740	transferase activity

0.61	GO:0005634	nucleus
0.34	GO:0043204	perikaryon
0.34	GO:0030424	axon
0.30	GO:0016020	membrane

0.33

GO:0004725

tr|T1G1C9|T1G1C9_HELRO
Uncharacterized protein
Search

0.82	Gamma-aminobutyric acid receptor subunit beta

0.61	GO:0007165	signal transduction
0.60	GO:0034220	ion transmembrane transport
0.39	GO:0006821	chloride transport
0.35	GO:0007268	chemical synaptic transmission
0.35	GO:0060078	regulation of postsynaptic membrane potential
0.35	GO:0043058	regulation of backward locomotion
0.34	GO:0010033	response to organic substance
0.34	GO:0032501	multicellular organismal process
0.34	GO:0006836	neurotransmitter transport
0.34	GO:0060828	regulation of canonical Wnt signaling pathway

0.76	GO:0004890	GABA-A receptor activity
0.76	GO:0005230	extracellular ligand-gated ion channel activity
0.40	GO:0016594	glycine binding
0.39	GO:0030594	neurotransmitter receptor activity
0.38	GO:0005254	chloride channel activity
0.37	GO:0099095	ligand-gated anion channel activity
0.34	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
0.33	GO:0005507	copper ion binding
0.33	GO:0005509	calcium ion binding

0.55	GO:0005886	plasma membrane
0.43	GO:1902711	GABA-A receptor complex
0.38	GO:0098794	postsynapse
0.37	GO:0034707	chloride channel complex
0.36	GO:0030054	cell junction
0.35	GO:0030285	integral component of synaptic vesicle membrane
0.34	GO:0031594	neuromuscular junction

0.34

EC:1.14.17

GO:0016715

tr|T1G1D0|T1G1D0_HELRO
Uncharacterized protein
Search

RHBDD1

0.90	Rhomboid-related protein 4

0.61	GO:0006508	proteolysis
0.49	GO:0010954	positive regulation of protein processing
0.49	GO:0034620	cellular response to unfolded protein
0.48	GO:2000254	regulation of male germ cell proliferation
0.47	GO:0034644	cellular response to UV
0.47	GO:0048515	spermatid differentiation
0.46	GO:0043687	post-translational protein modification
0.46	GO:1903513	endoplasmic reticulum to cytosol transport
0.46	GO:0032527	protein exit from endoplasmic reticulum
0.46	GO:0034976	response to endoplasmic reticulum stress

0.69	GO:0004252	serine-type endopeptidase activity
0.37	GO:0005515	protein binding

0.49	GO:0044322	endoplasmic reticulum quality control compartment
0.45	GO:0030176	integral component of endoplasmic reticulum membrane
0.39	GO:0005739	mitochondrion

0.69

GO:0004252

tr|T1G1D1|T1G1D1_HELRO
Uncharacterized protein
Search

0.77	Musashi RNA binding protein 2

0.48	GO:0048864	stem cell development
0.40	GO:0021772	olfactory bulb development

0.56	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.48	GO:0005844	polysome
0.36	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1G1D2|T1G1D2_HELRO
Uncharacterized protein
Search

0.35	GO:0007264	small GTPase mediated signal transduction
0.35	GO:0043547	positive regulation of GTPase activity
0.34	GO:0071526	semaphorin-plexin signaling pathway
0.34	GO:0007283	spermatogenesis
0.34	GO:0015031	protein transport
0.34	GO:0006325	chromatin organization

0.36	GO:0005093	Rab GDP-dissociation inhibitor activity
0.35	GO:0005096	GTPase activator activity
0.35	GO:0003723	RNA binding
0.34	GO:0017154	semaphorin receptor activity

0.61	GO:0005634	nucleus
0.43	GO:0031974	membrane-enclosed lumen
0.40	GO:0044446	intracellular organelle part
0.37	GO:0045171	intercellular bridge
0.34	GO:0005694	chromosome
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|T1G1D3|T1G1D3_HELRO
Uncharacterized protein
Search

0.65	GO:1990255	subsynaptic reticulum organization
0.62	GO:0051124	synaptic growth at neuromuscular junction
0.62	GO:2000050	regulation of non-canonical Wnt signaling pathway
0.44	GO:0098698	postsynaptic specialization assembly
0.44	GO:1904861	excitatory synapse assembly
0.44	GO:0097106	postsynaptic density organization
0.44	GO:0006888	ER to Golgi vesicle-mediated transport
0.42	GO:0006901	vesicle coating
0.42	GO:0048199	vesicle targeting, to, from or within Golgi
0.42	GO:0048194	Golgi vesicle budding

0.45	GO:0005216	ion channel activity
0.45	GO:0030160	GKAP/Homer scaffold activity
0.41	GO:0008093	cytoskeletal adaptor activity
0.41	GO:0051117	ATPase binding
0.41	GO:0030507	spectrin binding
0.39	GO:0016301	kinase activity
0.39	GO:0018024	histone-lysine N-methyltransferase activity
0.38	GO:0015085	calcium ion transmembrane transporter activity
0.38	GO:0008422	beta-glucosidase activity
0.38	GO:0022834	ligand-gated channel activity

0.60	GO:0031594	neuromuscular junction
0.59	GO:0014069	postsynaptic density
0.45	GO:1905369	endopeptidase complex
0.42	GO:0005654	nucleoplasm
0.42	GO:0014731	spectrin-associated cytoskeleton
0.41	GO:0005829	cytosol
0.40	GO:0043234	protein complex
0.40	GO:0000139	Golgi membrane
0.40	GO:0032421	stereocilium bundle
0.37	GO:0015630	microtubule cytoskeleton

0.39

EC:2.1.1.43

GO:0018024

tr|T1G1D4|T1G1D4_HELRO
Uncharacterized protein
Search

tr|T1G1D5|T1G1D5_HELRO
Uncharacterized protein
Search

0.52	Mitochondrial sulfide quinone oxidoreductase

0.52	GO:0055114	oxidation-reduction process
0.38	GO:0070219	cellular sulfide ion homeostasis
0.38	GO:0098849	cellular detoxification of cadmium ion
0.37	GO:0042762	regulation of sulfur metabolic process
0.37	GO:0046937	phytochelatin metabolic process
0.36	GO:0006750	glutathione biosynthetic process
0.36	GO:0044550	secondary metabolite biosynthetic process
0.35	GO:0070813	hydrogen sulfide metabolic process
0.34	GO:0007313	maternal specification of dorsal/ventral axis, oocyte, soma encoded
0.34	GO:0007306	eggshell chorion assembly

0.53	GO:0016491	oxidoreductase activity
0.36	GO:0071949	FAD binding
0.34	GO:0048038	quinone binding
0.33	GO:0003777	microtubule motor activity
0.33	GO:0008017	microtubule binding
0.33	GO:0003883	CTP synthase activity
0.33	GO:0004252	serine-type endopeptidase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.40	GO:0005739	mitochondrion
0.39	GO:0019866	organelle inner membrane
0.33	GO:0005874	microtubule
0.32	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.53

GO:0016491

tr|T1G1D6|T1G1D6_HELRO
Uncharacterized protein
Search

0.70	caltractin

0.44	GO:0000226	microtubule cytoskeleton organization
0.43	GO:0070925	organelle assembly
0.42	GO:0032465	regulation of cytokinesis
0.42	GO:0007283	spermatogenesis
0.41	GO:0022027	interkinetic nuclear migration
0.41	GO:0006289	nucleotide-excision repair
0.40	GO:0022402	cell cycle process
0.39	GO:0044782	cilium organization
0.39	GO:0120031	plasma membrane bounded cell projection assembly
0.36	GO:0051301	cell division

0.70	GO:0005509	calcium ion binding
0.47	GO:0032795	heterotrimeric G-protein binding
0.44	GO:0031683	G-protein beta/gamma-subunit complex binding
0.41	GO:0008017	microtubule binding
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.32	GO:0016787	hydrolase activity

0.46	GO:0071942	XPC complex
0.45	GO:0005814	centriole
0.44	GO:0032391	photoreceptor connecting cilium
0.44	GO:0036064	ciliary basal body
0.43	GO:0005813	centrosome
0.34	GO:0000922	spindle pole
0.30	GO:0016020	membrane

0.34

GO:0032440

tr|T1G1D7|T1G1D7_HELRO
Uncharacterized protein
Search

tr|T1G1D8|T1G1D8_HELRO
Uncharacterized protein
Search

0.61	GO:0006508	proteolysis
0.51	GO:2000347	positive regulation of hepatocyte proliferation
0.51	GO:0034769	basement membrane disassembly
0.51	GO:0010756	positive regulation of plasminogen activation
0.50	GO:0043923	positive regulation by host of viral transcription
0.50	GO:0010719	negative regulation of epithelial to mesenchymal transition
0.49	GO:0007313	maternal specification of dorsal/ventral axis, oocyte, soma encoded
0.48	GO:0050680	negative regulation of epithelial cell proliferation
0.48	GO:0030307	positive regulation of cell growth
0.48	GO:0007306	eggshell chorion assembly

0.69	GO:0004252	serine-type endopeptidase activity
0.55	GO:0070008	serine-type exopeptidase activity
0.43	GO:0015269	calcium-activated potassium channel activity
0.41	GO:0005044	scavenger receptor activity
0.34	GO:0005509	calcium ion binding
0.34	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.33	GO:0004222	metalloendopeptidase activity
0.33	GO:0008270	zinc ion binding
0.32	GO:0016301	kinase activity
0.32	GO:0016491	oxidoreductase activity

0.47	GO:0031965	nuclear membrane
0.45	GO:0009986	cell surface
0.44	GO:0005789	endoplasmic reticulum membrane
0.42	GO:0005887	integral component of plasma membrane
0.42	GO:0043025	neuronal cell body
0.41	GO:0005911	cell-cell junction
0.38	GO:0005576	extracellular region
0.36	GO:0030141	secretory granule
0.35	GO:0016324	apical plasma membrane

0.69

GO:0004252

tr|T1G1D9|T1G1D9_HELRO
Uncharacterized protein
Search

tr|T1G1E0|T1G1E0_HELRO
Uncharacterized protein
Search

DYNLT1

0.86	Dynein molecular motor protein light chain

0.81	GO:0019060	intracellular transport of viral protein in host cell
0.60	GO:0008090	retrograde axonal transport
0.57	GO:0008340	determination of adult lifespan
0.56	GO:0007286	spermatid development
0.48	GO:0000132	establishment of mitotic spindle orientation
0.47	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.47	GO:0050768	negative regulation of neurogenesis
0.45	GO:0010976	positive regulation of neuron projection development
0.45	GO:1905709	negative regulation of membrane permeability
0.44	GO:0035022	positive regulation of Rac protein signal transduction

0.73	GO:0042802	identical protein binding
0.59	GO:0051959	dynein light intermediate chain binding
0.58	GO:0097718	disordered domain specific binding
0.58	GO:0045505	dynein intermediate chain binding
0.49	GO:0046983	protein dimerization activity
0.45	GO:0003774	motor activity
0.42	GO:0008022	protein C-terminus binding
0.40	GO:0031681	G-protein beta-subunit binding
0.40	GO:0030742	GTP-dependent protein binding
0.35	GO:0042623	ATPase activity, coupled

0.79	GO:0030286	dynein complex
0.76	GO:0005881	cytoplasmic microtubule
0.72	GO:0099503	secretory vesicle
0.59	GO:0033267	axon part
0.58	GO:0044216	other organism cell
0.58	GO:0018995	host
0.58	GO:0120111	neuron projection cytoplasm
0.45	GO:0030426	growth cone
0.45	GO:0005819	spindle
0.44	GO:0044297	cell body

tr|T1G1E1|T1G1E1_HELRO
Transcription initiation factor IIA subunit 2
Search

0.73	Transcription initiation factor IIA subunit 2

0.79	GO:0006367	transcription initiation from RNA polymerase II promoter
0.58	GO:0006413	translational initiation
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.52	GO:0070897	DNA-templated transcriptional preinitiation complex assembly
0.49	GO:1902680	positive regulation of RNA biosynthetic process
0.46	GO:0044093	positive regulation of molecular function
0.35	GO:0042795	snRNA transcription by RNA polymerase II
0.34	GO:0006368	transcription elongation from RNA polymerase II promoter

0.59	GO:0003743	translation initiation factor activity
0.51	GO:0003713	transcription coactivator activity
0.49	GO:0017025	TBP-class protein binding
0.48	GO:0001103	RNA polymerase II repressing transcription factor binding
0.45	GO:0042803	protein homodimerization activity
0.44	GO:0046982	protein heterodimerization activity
0.44	GO:0001129	RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly
0.43	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.42	GO:0001104	RNA polymerase II transcription cofactor activity

0.83	GO:0005672	transcription factor TFIIA complex
0.46	GO:0005669	transcription factor TFIID complex
0.45	GO:0030054	cell junction
0.30	GO:0031224	intrinsic component of membrane

tr|T1G1E2|T1G1E2_HELRO
Uncharacterized protein
Search

0.41	Cobyrinic acid ac diamide synthase

0.67	GO:0006400	tRNA modification
0.35	GO:0007018	microtubule-based movement
0.33	GO:0006605	protein targeting
0.33	GO:0015992	proton transport
0.32	GO:0055085	transmembrane transport
0.32	GO:0015074	DNA integration

0.35	GO:0003777	microtubule motor activity
0.35	GO:0008017	microtubule binding
0.33	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0003723	RNA binding
0.32	GO:0046872	metal ion binding

0.34	GO:0098805	whole membrane
0.34	GO:0098588	bounding membrane of organelle
0.34	GO:0033176	proton-transporting V-type ATPase complex
0.34	GO:0044437	vacuolar part
0.33	GO:0098798	mitochondrial protein complex
0.33	GO:0044455	mitochondrial membrane part
0.33	GO:0019867	outer membrane
0.30	GO:0016021	integral component of membrane

tr|T1G1E3|T1G1E3_HELRO
Poly [ADP-ribose] polymerase
Search

0.29	Poly [ADP-ribose] polymerase

0.41	GO:1902216	positive regulation of interleukin-4-mediated signaling pathway
0.41	GO:0060331	negative regulation of response to interferon-gamma
0.40	GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein
0.40	GO:0060334	regulation of interferon-gamma-mediated signaling pathway
0.40	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein
0.39	GO:0006471	protein ADP-ribosylation
0.38	GO:0001960	negative regulation of cytokine-mediated signaling pathway
0.37	GO:0010629	negative regulation of gene expression

0.82	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.38	GO:0046872	metal ion binding
0.37	GO:0019899	enzyme binding
0.35	GO:0003676	nucleic acid binding

0.37

GO:0005829

cytosol

0.82

GO:0003950

tr|T1G1E4|T1G1E4_HELRO
Uncharacterized protein
Search

CHMP5

0.72	Charged multivesicular body protein 5

0.79	GO:0007034	vacuolar transport
0.38	GO:0071985	multivesicular body sorting pathway
0.37	GO:1901673	regulation of mitotic spindle assembly
0.37	GO:0000920	cell separation after cytokinesis
0.37	GO:0007080	mitotic metaphase plate congression
0.37	GO:0010824	regulation of centrosome duplication
0.37	GO:0006997	nucleus organization
0.35	GO:0015031	protein transport
0.35	GO:0046755	viral budding
0.34	GO:0016197	endosomal transport

0.37	GO:0045296	cadherin binding
0.34	GO:0004499	N,N-dimethylaniline monooxygenase activity
0.33	GO:0050661	NADP binding
0.33	GO:0050660	flavin adenine dinucleotide binding

0.37	GO:0010008	endosome membrane
0.37	GO:0005829	cytosol
0.34	GO:0036452	ESCRT complex
0.33	GO:0098796	membrane protein complex

0.34

EC:1.14.13.8

GO:0004499

tr|T1G1E5|T1G1E5_HELRO
Uncharacterized protein
Search

tr|T1G1E6|T1G1E6_HELRO
Uncharacterized protein
Search

GRB2

0.69	Growth factor receptor-bound protein 2 (Fragment)

0.73	GO:0007265	Ras protein signal transduction
0.53	GO:0018108	peptidyl-tyrosine phosphorylation
0.51	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.48	GO:0043408	regulation of MAPK cascade
0.48	GO:0030154	cell differentiation
0.47	GO:0009967	positive regulation of signal transduction
0.47	GO:0046777	protein autophosphorylation
0.46	GO:0048513	animal organ development
0.46	GO:0032868	response to insulin
0.46	GO:0031623	receptor internalization

0.55	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.49	GO:0046875	ephrin receptor binding
0.48	GO:0005070	SH3/SH2 adaptor activity
0.47	GO:0043560	insulin receptor substrate binding
0.47	GO:0005154	epidermal growth factor receptor binding
0.47	GO:0005168	neurotrophin TRKA receptor binding
0.47	GO:0017124	SH3 domain binding
0.46	GO:0001784	phosphotyrosine residue binding
0.45	GO:0019903	protein phosphatase binding
0.43	GO:0019901	protein kinase binding

0.48	GO:0070436	Grb2-EGFR complex
0.44	GO:0008180	COP9 signalosome
0.44	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.43	GO:0005768	endosome
0.43	GO:0005911	cell-cell junction
0.43	GO:0012506	vesicle membrane
0.42	GO:0005730	nucleolus
0.41	GO:0005654	nucleoplasm
0.40	GO:0045121	membrane raft
0.40	GO:0005794	Golgi apparatus

0.55	EC:2.7.10.2	GO:0004715
0.33	KEGG:R04545	GO:0046934

tr|T1G1E7|T1G1E7_HELRO
Guanine nucleotide-binding protein subunit gamma
Search

GNG7

0.70	Guanine nucleotide-binding protein subunit gamma

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.36	GO:0007168	receptor guanylyl cyclase signaling pathway
0.36	GO:0001662	behavioral fear response
0.36	GO:0045761	regulation of adenylate cyclase activity
0.35	GO:0007626	locomotory behavior
0.35	GO:0071377	cellular response to glucagon stimulus
0.34	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.34	GO:0006915	apoptotic process
0.34	GO:0000226	microtubule cytoskeleton organization
0.33	GO:0007602	phototransduction

0.64	GO:0004871	signal transducer activity
0.39	GO:0003924	GTPase activity
0.34	GO:0051015	actin filament binding
0.33	GO:0008017	microtubule binding
0.33	GO:0003995	acyl-CoA dehydrogenase activity
0.33	GO:0050660	flavin adenine dinucleotide binding

0.81	GO:1905360	GTPase complex
0.80	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.66	GO:0098797	plasma membrane protein complex
0.35	GO:0070062	extracellular exosome
0.33	GO:0005874	microtubule

0.33

EC:1.3.99.3

GO:0003995

tr|T1G1E8|T1G1E8_HELRO
Uncharacterized protein
Search

0.71	Small androgen receptor-interacting protein 1

0.71	GO:0002181	cytoplasmic translation
0.68	GO:1903833	positive regulation of cellular response to amino acid starvation
0.66	GO:0034198	cellular response to amino acid starvation
0.63	GO:0031333	negative regulation of protein complex assembly
0.63	GO:0006469	negative regulation of protein kinase activity
0.45	GO:0010998	regulation of translational initiation by eIF2 alpha phosphorylation
0.43	GO:0000077	DNA damage checkpoint
0.40	GO:0006260	DNA replication

0.64	GO:0004860	protein kinase inhibitor activity
0.45	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity
0.43	GO:0003697	single-stranded DNA binding
0.37	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0005515	protein binding

0.74

GO:0005844

polysome

0.45

GO:0004694

tr|T1G1E9|T1G1E9_HELRO
Uncharacterized protein
Search

tr|T1G1F0|T1G1F0_HELRO
Uncharacterized protein
Search

0.67	ATP synthase subunit gamma

0.69	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.69	GO:0006754	ATP biosynthetic process
0.68	GO:0099132	ATP hydrolysis coupled cation transmembrane transport

0.70	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism
0.38	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding

0.70	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)
0.38	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1G1F1|T1G1F1_HELRO
Uncharacterized protein
Search

0.69	Feline leukemia virus subgroup C cellular receptor family, member 2b

0.57	GO:0097037	heme export
0.56	GO:0030218	erythrocyte differentiation
0.53	GO:0048536	spleen development
0.53	GO:0060323	head morphogenesis
0.52	GO:0042733	embryonic digit morphogenesis
0.52	GO:0035264	multicellular organism growth
0.52	GO:0046620	regulation of organ growth
0.51	GO:0048704	embryonic skeletal system morphogenesis
0.51	GO:0055085	transmembrane transport
0.50	GO:0001568	blood vessel development

0.50	GO:0015232	heme transporter activity
0.35	GO:0020037	heme binding
0.35	GO:0104005	hijacked molecular function
0.33	GO:0030246	carbohydrate binding
0.33	GO:0005515	protein binding
0.32	GO:0016788	hydrolase activity, acting on ester bonds

0.42	GO:0005739	mitochondrion
0.34	GO:0005886	plasma membrane
0.34	GO:0031967	organelle envelope
0.34	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

0.32

GO:0016788

tr|T1G1F2|T1G1F2_HELRO
Uncharacterized protein
Search

LACTB2

0.46	Beta-lactamase protein 2

0.63	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.43	GO:0046777	protein autophosphorylation
0.34	GO:0055114	oxidation-reduction process

0.70	GO:0003727	single-stranded RNA binding
0.63	GO:0004521	endoribonuclease activity
0.57	GO:0008270	zinc ion binding
0.43	GO:0004712	protein serine/threonine/tyrosine kinase activity
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0016491	oxidoreductase activity

0.67	GO:0005759	mitochondrial matrix
0.30	GO:0031224	intrinsic component of membrane

0.43

EC:2.7.12.1

GO:0004712

tr|T1G1F3|T1G1F3_HELRO
Uncharacterized protein
Search

0.87	Voltage dependent calcium channel

0.77	GO:0034765	regulation of ion transmembrane transport
0.77	GO:0070588	calcium ion transmembrane transport
0.42	GO:0035545	determination of left/right asymmetry in nervous system
0.41	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.40	GO:0007626	locomotory behavior
0.39	GO:0042594	response to starvation
0.39	GO:0009408	response to heat
0.38	GO:0001505	regulation of neurotransmitter levels
0.37	GO:0086010	membrane depolarization during action potential

0.82	GO:0005245	voltage-gated calcium channel activity
0.67	GO:0005509	calcium ion binding
0.39	GO:0008022	protein C-terminus binding

0.81	GO:0005891	voltage-gated calcium channel complex
0.43	GO:0048787	presynaptic active zone membrane

tr|T1G1F4|T1G1F4_HELRO
Uncharacterized protein
Search

0.39	Thioredoxin domain-containing protein 9

0.68	GO:0045454	cell redox homeostasis
0.43	GO:0008616	queuosine biosynthetic process
0.34	GO:0033227	dsRNA transport

0.48	GO:0045296	cadherin binding
0.45	GO:0008479	queuine tRNA-ribosyltransferase activity
0.35	GO:0051032	nucleic acid transmembrane transporter activity

0.49	GO:0030496	midbody
0.46	GO:0005813	centrosome
0.43	GO:0005829	cytosol
0.41	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.45

EC:2.4.2.29

GO:0008479

tr|T1G1F5|T1G1F5_HELRO
Uncharacterized protein
Search

MITD1

0.93	Microtubule interacting and trafficking domain containing 1

0.79	GO:0000920	cell separation after cytokinesis
0.78	GO:0032091	negative regulation of protein binding
0.74	GO:0000281	mitotic cytokinesis
0.42	GO:0030163	protein catabolic process
0.41	GO:0071985	multivesicular body sorting pathway
0.41	GO:0039702	viral budding via host ESCRT complex
0.39	GO:0006508	proteolysis

0.70	GO:0019904	protein domain specific binding
0.70	GO:0035091	phosphatidylinositol binding
0.69	GO:0042803	protein homodimerization activity
0.44	GO:0004176	ATP-dependent peptidase activity
0.42	GO:0004252	serine-type endopeptidase activity
0.37	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0008270	zinc ion binding
0.33	GO:0003676	nucleic acid binding

0.76	GO:0030496	midbody
0.69	GO:0019898	extrinsic component of membrane
0.53	GO:0043231	intracellular membrane-bounded organelle
0.45	GO:0008537	proteasome activator complex
0.44	GO:0031902	late endosome membrane
0.41	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.42

GO:0004252

tr|T1G1F6|T1G1F6_HELRO
Uncharacterized protein
Search

TYW3

0.51	tRNA wybutosine-synthesizing protein 3

0.66	GO:0031591	wybutosine biosynthetic process
0.58	GO:0030488	tRNA methylation
0.37	GO:0006278	RNA-dependent DNA biosynthetic process
0.34	GO:0006486	protein glycosylation

0.58	GO:0008175	tRNA methyltransferase activity
0.37	GO:0003964	RNA-directed DNA polymerase activity
0.34	GO:0102522	tRNA 4-demethylwyosine alpha-amino-alpha-carboxypropyltransferase activity
0.33	GO:0016757	transferase activity, transferring glycosyl groups
0.33	GO:0046872	metal ion binding

0.30

GO:0031224

intrinsic component of membrane

0.58

GO:0008175

tr|T1G1F7|T1G1F7_HELRO
Alpha-1,3-glucosyltransferase
Search

ALG6

0.60	Alpha-1,3-glucosyltransferase

0.73	GO:0006486	protein glycosylation
0.46	GO:0006490	oligosaccharide-lipid intermediate biosynthetic process
0.36	GO:0040003	chitin-based cuticle development
0.34	GO:0008299	isoprenoid biosynthetic process
0.33	GO:0006098	pentose-phosphate shunt
0.33	GO:0009060	aerobic respiration
0.33	GO:0016310	phosphorylation
0.33	GO:0005975	carbohydrate metabolic process

0.69	GO:0016758	transferase activity, transferring hexosyl groups
0.35	GO:0019706	protein-cysteine S-palmitoyltransferase activity
0.35	GO:0004496	mevalonate kinase activity
0.34	GO:0004801	sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity
0.34	GO:0035091	phosphatidylinositol binding
0.33	GO:0008080	N-acetyltransferase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.72	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.69	EC:2.4.1	GO:0016758
0.35	KEGG:R02245	GO:0004496

tr|T1G1F8|T1G1F8_HELRO
Uncharacterized protein
Search

tr|T1G1F9|T1G1F9_HELRO
Uncharacterized protein
Search

0.60	GO:0009395	phospholipid catabolic process
0.58	GO:0035556	intracellular signal transduction
0.55	GO:0018108	peptidyl-tyrosine phosphorylation
0.52	GO:0046777	protein autophosphorylation
0.48	GO:0045087	innate immune response
0.48	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.47	GO:0042127	regulation of cell proliferation
0.45	GO:0030154	cell differentiation
0.41	GO:0016477	cell migration
0.35	GO:0034220	ion transmembrane transport

0.66	GO:0004435	phosphatidylinositol phospholipase C activity
0.57	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.53	GO:0004871	signal transducer activity
0.51	GO:0005509	calcium ion binding
0.45	GO:0005102	receptor binding
0.42	GO:0032559	adenyl ribonucleotide binding
0.42	GO:0008144	drug binding
0.42	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0003779	actin binding
0.35	GO:0015075	ion transmembrane transporter activity

0.48	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.37	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.66	EC:3.1.4.11	GO:0004435
0.66	KEGG:R03435	GO:0004435

tr|T1G1G0|T1G1G0_HELRO
Innexin
Search

INX

0.65	Innexin unc-9

0.58	GO:0006811	ion transport
0.43	GO:0006367	transcription initiation from RNA polymerase II promoter
0.37	GO:0048598	embryonic morphogenesis
0.36	GO:0010644	cell communication by electrical coupling
0.33	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:0055085	transmembrane transport

0.37	GO:0005243	gap junction channel activity
0.33	GO:0004930	G-protein coupled receptor activity

0.80	GO:0005921	gap junction
0.55	GO:0005886	plasma membrane
0.43	GO:0005669	transcription factor TFIID complex
0.35	GO:0045202	synapse
0.33	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

tr|T1G1G1|T1G1G1_HELRO
Uncharacterized protein
Search

tr|T1G1G2|T1G1G2_HELRO
Uncharacterized protein
Search

0.59	GO:0003723	RNA binding
0.58	GO:0008270	zinc ion binding

0.30

GO:0044425

membrane part

tr|T1G1G3|T1G1G3_HELRO
Uncharacterized protein
Search

0.49	GO:0034220	ion transmembrane transport
0.44	GO:0016310	phosphorylation
0.43	GO:0006464	cellular protein modification process

0.54	GO:0005216	ion channel activity
0.46	GO:0016301	kinase activity
0.43	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.42	GO:0140096	catalytic activity, acting on a protein
0.41	GO:0016757	transferase activity, transferring glycosyl groups
0.41	GO:0030554	adenyl nucleotide binding
0.40	GO:0097367	carbohydrate derivative binding
0.40	GO:0008144	drug binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0044425

membrane part

0.43

GO:0016773

tr|T1G1G4|T1G1G4_HELRO
Uncharacterized protein
Search

DNAI2

0.89	Axonemal outer arm dynein intermediate chain 1

0.85	GO:0036158	outer dynein arm assembly
0.73	GO:0003341	cilium movement
0.66	GO:0007368	determination of left/right symmetry
0.61	GO:0046692	sperm competition
0.60	GO:0010996	response to auditory stimulus
0.56	GO:0007605	sensory perception of sound
0.37	GO:1902476	chloride transmembrane transport

0.68	GO:0045504	dynein heavy chain binding
0.67	GO:0045503	dynein light chain binding
0.66	GO:0003777	microtubule motor activity
0.52	GO:0042623	ATPase activity, coupled
0.39	GO:0008017	microtubule binding
0.38	GO:0005254	chloride channel activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.78	GO:0036157	outer dynein arm
0.67	GO:0036126	sperm flagellum
0.65	GO:0009897	external side of plasma membrane
0.56	GO:0043025	neuronal cell body
0.56	GO:0030425	dendrite
0.42	GO:0005874	microtubule
0.38	GO:0034707	chloride channel complex

tr|T1G1G5|T1G1G5_HELRO
Uncharacterized protein
Search

tr|T1G1G6|T1G1G6_HELRO
Uncharacterized protein
Search

tr|T1G1G7|T1G1G7_HELRO
Uncharacterized protein
Search

0.81	Class a scavenger receptor srcr domain with lysyl oxidase domain, nb: only one srcr domain

0.71	GO:0006898	receptor-mediated endocytosis
0.53	GO:0055114	oxidation-reduction process
0.47	GO:1902455	negative regulation of stem cell population maintenance
0.46	GO:0002040	sprouting angiogenesis
0.46	GO:0032332	positive regulation of chondrocyte differentiation
0.46	GO:0001935	endothelial cell proliferation
0.45	GO:0010718	positive regulation of epithelial to mesenchymal transition
0.45	GO:0030199	collagen fibril organization
0.45	GO:0070828	heterochromatin organization
0.45	GO:0043542	endothelial cell migration

0.81	GO:0005044	scavenger receptor activity
0.77	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor
0.72	GO:0005507	copper ion binding
0.46	GO:0070492	oligosaccharide binding
0.38	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0005515	protein binding
0.33	GO:0009055	electron transfer activity

0.42	GO:0005615	extracellular space
0.41	GO:0000785	chromatin
0.41	GO:0005783	endoplasmic reticulum
0.40	GO:0005654	nucleoplasm
0.37	GO:0005604	basement membrane
0.35	GO:0043235	receptor complex
0.30	GO:0016020	membrane

0.77

EC:1.4.3

GO:0016641

tr|T1G1G8|T1G1G8_HELRO
Uncharacterized protein
Search

APOA1BP

0.66	NAD(P)H-hydrate epimerase

0.51	GO:0051289	protein homotetramerization
0.49	GO:0019362	pyridine nucleotide metabolic process
0.35	GO:0031580	membrane raft distribution
0.35	GO:0010874	regulation of cholesterol efflux
0.35	GO:0002040	sprouting angiogenesis
0.35	GO:0016525	negative regulation of angiogenesis
0.34	GO:0006836	neurotransmitter transport
0.33	GO:0072525	pyridine-containing compound biosynthetic process
0.33	GO:0009108	coenzyme biosynthetic process
0.33	GO:0009165	nucleotide biosynthetic process

0.77	GO:0052856	NADHX epimerase activity
0.52	GO:0046872	metal ion binding
0.51	GO:1901265	nucleoside phosphate binding
0.50	GO:0036094	small molecule binding
0.49	GO:0052857	NADPHX epimerase activity
0.47	GO:0042803	protein homodimerization activity
0.34	GO:0052855	ADP-dependent NAD(P)H-hydrate dehydratase activity
0.34	GO:0008641	ubiquitin-like modifier activating enzyme activity
0.34	GO:0005328	neurotransmitter:sodium symporter activity
0.32	GO:0016787	hydrolase activity

0.53	GO:0005739	mitochondrion
0.52	GO:0005576	extracellular region
0.50	GO:0044297	cell body
0.48	GO:0005929	cilium
0.46	GO:0005654	nucleoplasm
0.45	GO:0005829	cytosol
0.35	GO:0031982	vesicle
0.30	GO:0031224	intrinsic component of membrane

0.77

EC:5.1

GO:0052856

tr|T1G1G9|T1G1G9_HELRO
Uncharacterized protein
Search

UROC1

0.49	urocanate hydratase

0.46	GO:0006548	histidine catabolic process
0.38	GO:0043606	formamide metabolic process
0.37	GO:0015942	formate metabolic process
0.37	GO:0006536	glutamate metabolic process
0.32	GO:0016310	phosphorylation

0.82	GO:0016153	urocanate hydratase activity
0.33	GO:0016301	kinase activity
0.32	GO:0003676	nucleic acid binding

0.43	GO:0005829	cytosol
0.30	GO:0044425	membrane part

0.82	EC:4.2.1.49	GO:0016153
0.82	KEGG:R02914	GO:0016153

tr|T1G1H0|T1G1H0_HELRO
Uncharacterized protein
Search

0.53	GO:0007420	brain development
0.52	GO:0014912	negative regulation of smooth muscle cell migration
0.52	GO:0014911	positive regulation of smooth muscle cell migration
0.47	GO:0042048	olfactory behavior
0.47	GO:0001700	embryonic development via the syncytial blastoderm
0.40	GO:0006508	proteolysis
0.36	GO:0050919	negative chemotaxis
0.35	GO:0030154	cell differentiation
0.34	GO:0046901	tetrahydrofolylpolyglutamate biosynthetic process
0.34	GO:0007018	microtubule-based movement

0.52	GO:0030215	semaphorin receptor binding
0.43	GO:0008237	metallopeptidase activity
0.38	GO:0046872	metal ion binding
0.34	GO:0004326	tetrahydrofolylpolyglutamate synthase activity
0.34	GO:0003777	microtubule motor activity
0.34	GO:0008017	microtubule binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0003677	DNA binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.46	GO:0005794	Golgi apparatus
0.41	GO:0005886	plasma membrane
0.35	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:6.3.2.17

GO:0004326

tr|T1G1H1|T1G1H1_HELRO
Uncharacterized protein
Search

0.84	Zinc finger protein sens

0.55	GO:2001141	regulation of RNA biosynthetic process
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.51	GO:0051569	regulation of histone H3-K4 methylation
0.49	GO:0030097	hemopoiesis
0.44	GO:0016360	sensory organ precursor cell fate determination
0.44	GO:0008594	photoreceptor cell morphogenesis
0.43	GO:0008407	chaeta morphogenesis
0.43	GO:0051253	negative regulation of RNA metabolic process
0.43	GO:0010558	negative regulation of macromolecule biosynthetic process

0.51	GO:0003676	nucleic acid binding
0.43	GO:0043425	bHLH transcription factor binding
0.42	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.42	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.37	GO:0046872	metal ion binding
0.36	GO:0003714	transcription corepressor activity
0.35	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.35	GO:0001104	RNA polymerase II transcription cofactor activity
0.33	GO:0001085	RNA polymerase II transcription factor binding
0.33	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding

0.42	GO:0005700	polytene chromosome
0.42	GO:0005634	nucleus
0.40	GO:0005819	spindle
0.39	GO:0070013	intracellular organelle lumen
0.33	GO:0005667	transcription factor complex
0.31	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.31

GO:0016740

tr|T1G1H2|T1G1H2_HELRO
Uncharacterized protein
Search

TRHR

0.90	Thyrotropin-releasing hormone receptor b

0.68	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:0018108	peptidyl-tyrosine phosphorylation

0.85	GO:0004997	thyrotropin-releasing hormone receptor activity
0.34	GO:0004715	non-membrane spanning protein tyrosine kinase activity

0.34	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

0.34

GO:0004715

tr|T1G1H3|T1G1H3_HELRO
Uncharacterized protein
Search

0.46	GO:2001141	regulation of RNA biosynthetic process
0.46	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.46	GO:0010468	regulation of gene expression
0.44	GO:0051253	negative regulation of RNA metabolic process
0.44	GO:0010558	negative regulation of macromolecule biosynthetic process
0.44	GO:0031327	negative regulation of cellular biosynthetic process
0.42	GO:0071157	negative regulation of cell cycle arrest
0.41	GO:0030335	positive regulation of cell migration
0.41	GO:0008285	negative regulation of cell proliferation
0.40	GO:0008284	positive regulation of cell proliferation

0.51	GO:0003676	nucleic acid binding
0.43	GO:0046872	metal ion binding
0.40	GO:0003700	DNA binding transcription factor activity
0.34	GO:0001222	transcription corepressor binding
0.33	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.33	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
0.33	GO:0071949	FAD binding

0.40	GO:0005634	nucleus
0.39	GO:0015629	actin cytoskeleton
0.39	GO:0005829	cytosol
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part
0.33	GO:0019898	extrinsic component of membrane
0.32	GO:0005794	Golgi apparatus
0.32	GO:0042995	cell projection
0.32	GO:0031090	organelle membrane
0.32	GO:0005739	mitochondrion

0.33

EC:1.14.14

GO:0016712

tr|T1G1H4|T1G1H4_HELRO
Methionine aminopeptidase
Search

0.46	Methionine aminopeptidase

0.73	GO:0070084	protein initiator methionine removal
0.61	GO:0006508	proteolysis
0.35	GO:0048203	vesicle targeting, trans-Golgi to endosome
0.35	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading
0.34	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation
0.34	GO:2000146	negative regulation of cell motility
0.33	GO:0007018	microtubule-based movement
0.33	GO:0042254	ribosome biogenesis
0.33	GO:0051604	protein maturation
0.33	GO:0010629	negative regulation of gene expression

0.74	GO:0008235	metalloexopeptidase activity
0.71	GO:0004177	aminopeptidase activity
0.54	GO:0046872	metal ion binding
0.39	GO:0016758	transferase activity, transferring hexosyl groups
0.35	GO:0035650	AP-1 adaptor complex binding
0.33	GO:0003729	mRNA binding
0.33	GO:0003777	microtubule motor activity
0.33	GO:0008017	microtubule binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding

0.34	GO:0005829	cytosol
0.34	GO:0010494	cytoplasmic stress granule
0.33	GO:0005634	nucleus
0.32	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.71

EC:3.4.11

GO:0004177

tr|T1G1H5|T1G1H5_HELRO
Uncharacterized protein
Search

RNF11

0.79	RING finger protein 11

0.75	GO:0051865	protein autoubiquitination
0.72	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.62	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process

0.70	GO:0004842	ubiquitin-protein transferase activity
0.61	GO:0061659	ubiquitin-like protein ligase activity
0.43	GO:0016874	ligase activity
0.38	GO:0005515	protein binding
0.37	GO:0046872	metal ion binding
0.34	GO:0003677	DNA binding

0.67	GO:0000151	ubiquitin ligase complex
0.44	GO:0055037	recycling endosome
0.44	GO:0005769	early endosome
0.39	GO:0005634	nucleus
0.38	GO:0070062	extracellular exosome

0.43	EC:6	GO:0016874
0.70	KEGG:R03876	GO:0004842

tr|T1G1H6|T1G1H6_HELRO
Uncharacterized protein
Search

0.66	Centriolin

0.66	GO:0000278	mitotic cell cycle
0.59	GO:0051301	cell division
0.54	GO:0034162	toll-like receptor 9 signaling pathway
0.51	GO:0050729	positive regulation of inflammatory response
0.51	GO:0002755	MyD88-dependent toll-like receptor signaling pathway
0.51	GO:0050707	regulation of cytokine secretion
0.50	GO:0002237	response to molecule of bacterial origin
0.50	GO:0045087	innate immune response
0.40	GO:0120036	plasma membrane bounded cell projection organization
0.39	GO:0032741	positive regulation of interleukin-18 production

0.46	GO:0004888	transmembrane signaling receptor activity
0.40	GO:0016301	kinase activity
0.37	GO:0005149	interleukin-1 receptor binding
0.37	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.36	GO:0140096	catalytic activity, acting on a protein
0.36	GO:0035197	siRNA binding
0.36	GO:0045322	unmethylated CpG binding
0.35	GO:0003779	actin binding
0.35	GO:0005524	ATP binding
0.35	GO:0042803	protein homodimerization activity

0.54	GO:0120103	centriolar subdistal appendage
0.49	GO:0005813	centrosome
0.45	GO:0005829	cytosol
0.39	GO:0032009	early phagosome
0.39	GO:0097431	mitotic spindle pole
0.39	GO:0036019	endolysosome
0.38	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0090543	Flemming body
0.36	GO:0005783	endoplasmic reticulum
0.36	GO:0005578	proteinaceous extracellular matrix

0.37

GO:0016773

tr|T1G1H7|T1G1H7_HELRO
Uncharacterized protein
Search

0.10	DNA replication complex GINS protein SLD5

0.70	GO:0006261	DNA-dependent DNA replication
0.61	GO:0001833	inner cell mass cell proliferation
0.49	GO:0000727	double-strand break repair via break-induced replication
0.44	GO:0032392	DNA geometric change
0.36	GO:0022616	DNA strand elongation

0.47	GO:0043138	3'-5' DNA helicase activity
0.35	GO:0003682	chromatin binding
0.35	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.45	GO:0005657	replication fork
0.45	GO:0032993	protein-DNA complex
0.43	GO:0031974	membrane-enclosed lumen
0.40	GO:0043234	protein complex
0.40	GO:0005737	cytoplasm

tr|T1G1H8|T1G1H8_HELRO
4-hydroxybenzoate polyprenyltransferase, mitochondrial
Search

COQ2

0.54	4-hydroxybenzoate polyprenyltransferase, mitochondrial

0.72	GO:0006744	ubiquinone biosynthetic process
0.64	GO:0008299	isoprenoid biosynthetic process
0.45	GO:0048009	insulin-like growth factor receptor signaling pathway
0.44	GO:0050830	defense response to Gram-positive bacterium
0.44	GO:0008340	determination of adult lifespan
0.43	GO:0050829	defense response to Gram-negative bacterium
0.43	GO:0050832	defense response to fungus
0.34	GO:0006360	transcription by RNA polymerase I
0.34	GO:0006383	transcription by RNA polymerase III

0.77	GO:0047293	4-hydroxybenzoate nonaprenyltransferase activity
0.77	GO:0002083	4-hydroxybenzoate decaprenyltransferase activity
0.49	GO:0008412	4-hydroxybenzoate octaprenyltransferase activity
0.34	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.33	GO:0003676	nucleic acid binding

0.72	GO:0031305	integral component of mitochondrial inner membrane
0.39	GO:0005886	plasma membrane
0.35	GO:0005666	DNA-directed RNA polymerase III complex
0.34	GO:0005736	DNA-directed RNA polymerase I complex

0.77

EC:2.5.1.39

GO:0047293

tr|T1G1H9|T1G1H9_HELRO
Uncharacterized protein
Search

0.90	Mitochondrial carrier triple repeat protein 1

0.43	GO:0006839	mitochondrial transport
0.38	GO:0055085	transmembrane transport

0.38	GO:0022857	transmembrane transporter activity
0.34	GO:0030246	carbohydrate binding

0.40	GO:0005739	mitochondrion
0.39	GO:0019866	organelle inner membrane
0.30	GO:0044425	membrane part

tr|T1G1I0|T1G1I0_HELRO
Uncharacterized protein
Search

SPCS2

0.92	Signal peptidase complex subunit 2

0.80	GO:0006465	signal peptide processing
0.45	GO:0045047	protein targeting to ER
0.37	GO:0051260	protein homooligomerization
0.37	GO:0034765	regulation of ion transmembrane transport
0.36	GO:0071804	cellular potassium ion transport
0.35	GO:0032367	intracellular cholesterol transport
0.35	GO:0098662	inorganic cation transmembrane transport
0.34	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.34	GO:0007186	G-protein coupled receptor signaling pathway

0.61	GO:0008233	peptidase activity
0.37	GO:0005249	voltage-gated potassium channel activity
0.35	GO:0017127	cholesterol transporter activity
0.34	GO:0004984	olfactory receptor activity
0.34	GO:0004308	exo-alpha-sialidase activity
0.34	GO:0004930	G-protein coupled receptor activity
0.33	GO:0016887	ATPase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.82	GO:0005787	signal peptidase complex
0.37	GO:0031090	organelle membrane
0.37	GO:0008076	voltage-gated potassium channel complex

0.61

GO:0008233

tr|T1G1I1|T1G1I1_HELRO
Uncharacterized protein
Search

PBX3

0.87	Pre-B-cell leukemia transcription factor

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.42	GO:0002087	regulation of respiratory gaseous exchange by neurological system process
0.42	GO:0021516	dorsal spinal cord development
0.41	GO:0007585	respiratory gaseous exchange
0.41	GO:0008344	adult locomotory behavior
0.40	GO:0048468	cell development
0.40	GO:0051254	positive regulation of RNA metabolic process
0.40	GO:0010557	positive regulation of macromolecule biosynthetic process

0.61	GO:0003700	DNA binding transcription factor activity
0.59	GO:0043565	sequence-specific DNA binding
0.43	GO:0035326	enhancer binding
0.39	GO:0001012	RNA polymerase II regulatory region DNA binding
0.38	GO:0003690	double-stranded DNA binding
0.37	GO:0033613	activating transcription factor binding
0.36	GO:0003713	transcription coactivator activity
0.36	GO:0046982	protein heterodimerization activity
0.30	GO:0003824	catalytic activity

0.61	GO:0005634	nucleus
0.41	GO:0005667	transcription factor complex
0.35	GO:0032993	protein-DNA complex
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|T1G1I2|T1G1I2_HELRO
Uncharacterized protein
Search

0.70	Phosphatidylinositol 4-phosphate 5-kinase type-1 beta

0.75	GO:0046854	phosphatidylinositol phosphorylation
0.39	GO:0006661	phosphatidylinositol biosynthetic process
0.36	GO:0014066	regulation of phosphatidylinositol 3-kinase signaling

0.82	GO:0016307	phosphatidylinositol phosphate kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0052812	phosphatidylinositol-3,4-bisphosphate 5-kinase activity
0.38	GO:0052810	1-phosphatidylinositol-5-kinase activity
0.36	GO:0017056	structural constituent of nuclear pore
0.35	GO:0005515	protein binding

0.42	GO:0001931	uropod
0.38	GO:0005829	cytosol
0.37	GO:0012505	endomembrane system
0.30	GO:0016020	membrane

0.82

GO:0016307

tr|T1G1I3|T1G1I3_HELRO
Uncharacterized protein
Search

0.87	disks large homolog 1 isoform X16

0.79	GO:0046710	GDP metabolic process
0.76	GO:0046037	GMP metabolic process

0.79

GO:0004385

guanylate kinase activity

0.79

GO:0004385

tr|T1G1I4|T1G1I4_HELRO
Uncharacterized protein
Search

0.10	Regulating synaptic membrane exocytosis protein 2

0.63	GO:0006886	intracellular protein transport
0.54	GO:0070073	clustering of voltage-gated calcium channels
0.51	GO:0007274	neuromuscular synaptic transmission
0.51	GO:0006887	exocytosis
0.50	GO:0048167	regulation of synaptic plasticity
0.44	GO:0048489	synaptic vesicle transport
0.44	GO:0099504	synaptic vesicle cycle
0.44	GO:0099643	signal release from synapse
0.44	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.42	GO:0006836	neurotransmitter transport

0.76	GO:0017137	Rab GTPase binding
0.51	GO:0046872	metal ion binding
0.34	GO:0004421	hydroxymethylglutaryl-CoA synthase activity

0.58	GO:0048786	presynaptic active zone
0.48	GO:0099569	presynaptic cytoskeleton
0.45	GO:0099738	cell cortex region
0.44	GO:0030863	cortical cytoskeleton
0.44	GO:0008021	synaptic vesicle
0.30	GO:0016020	membrane

0.34	EC:2.3.3.10	GO:0004421
0.34	KEGG:R01978	GO:0004421

tr|T1G1I5|T1G1I5_HELRO
Uncharacterized protein
Search

0.74	GO:0007018	microtubule-based movement
0.70	GO:0099518	vesicle cytoskeletal trafficking
0.48	GO:0035459	cargo loading into vesicle
0.48	GO:0032438	melanosome organization
0.47	GO:0008333	endosome to lysosome transport
0.45	GO:0032465	regulation of cytokinesis
0.43	GO:0006886	intracellular protein transport
0.36	GO:0043001	Golgi to plasma membrane protein transport
0.36	GO:0036049	peptidyl-lysine desuccinylation
0.36	GO:0036047	peptidyl-lysine demalonylation

0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0016887	ATPase activity
0.36	GO:0036055	protein-succinyllysine desuccinylase activity
0.36	GO:0036054	protein-malonyllysine demalonylase activity
0.36	GO:0034979	NAD-dependent protein deacetylase activity
0.35	GO:0070403	NAD+ binding

0.47	GO:0015630	microtubule cytoskeleton
0.47	GO:0044430	cytoskeletal part
0.46	GO:0030496	midbody
0.45	GO:0010008	endosome membrane
0.42	GO:0099512	supramolecular fiber
0.37	GO:0043234	protein complex
0.37	GO:0032588	trans-Golgi network membrane
0.35	GO:0005829	cytosol
0.34	GO:0005634	nucleus
0.34	GO:0005739	mitochondrion

0.37

EC:3.6.1.3

GO:0016887

tr|T1G1I6|T1G1I6_HELRO
Uncharacterized protein
Search

PTRHD1

0.83	Peptidyl-tRNA hydrolase domain containing 1

0.36	GO:0035335	peptidyl-tyrosine dephosphorylation
0.35	GO:0016567	protein ubiquitination
0.35	GO:0006171	cAMP biosynthetic process
0.33	GO:0035556	intracellular signal transduction
0.33	GO:0006182	cGMP biosynthetic process
0.33	GO:0016569	covalent chromatin modification
0.32	GO:0006351	transcription, DNA-templated
0.32	GO:0006355	regulation of transcription, DNA-templated

0.78	GO:0004045	aminoacyl-tRNA hydrolase activity
0.37	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity
0.36	GO:0003993	acid phosphatase activity
0.35	GO:0004016	adenylate cyclase activity
0.33	GO:0004383	guanylate cyclase activity
0.33	GO:0003723	RNA binding
0.32	GO:1901265	nucleoside phosphate binding
0.32	GO:0036094	small molecule binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding

0.34	GO:0008074	guanylate cyclase complex, soluble
0.33	GO:0016580	Sin3 complex
0.33	GO:0035267	NuA4 histone acetyltransferase complex
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.78

EC:3.1.1.29

GO:0004045

tr|T1G1I7|T1G1I7_HELRO
Uncharacterized protein
Search

0.75	Heparan-sulfate 6-O-sulfotransferase

0.54	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification
0.41	GO:0001569	branching involved in blood vessel morphogenesis
0.41	GO:0048048	embryonic eye morphogenesis
0.35	GO:0040018	positive regulation of multicellular organism growth
0.34	GO:0007517	muscle organ development
0.33	GO:0030154	cell differentiation
0.33	GO:0006024	glycosaminoglycan biosynthetic process
0.32	GO:0006468	protein phosphorylation

0.78	GO:0008146	sulfotransferase activity
0.33	GO:0004674	protein serine/threonine kinase activity
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0008144	drug binding

0.39	GO:0005654	nucleoplasm
0.35	GO:0070062	extracellular exosome
0.33	GO:0000139	Golgi membrane
0.30	GO:0016021	integral component of membrane

0.78

EC:2.8.2

GO:0008146

tr|T1G1I8|T1G1I8_HELRO
Uncharacterized protein
Search

SNX29

0.53	Sorting nexin 29

0.37	GO:0007018	microtubule-based movement
0.35	GO:0030705	cytoskeleton-dependent intracellular transport
0.33	GO:0043043	peptide biosynthetic process
0.33	GO:0007264	small GTPase mediated signal transduction
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process

0.76	GO:0035091	phosphatidylinositol binding
0.37	GO:0003777	microtubule motor activity
0.35	GO:0016887	ATPase activity
0.34	GO:0003924	GTPase activity
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0019001	guanyl nucleotide binding
0.33	GO:0003735	structural constituent of ribosome
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.38	GO:0005871	kinesin complex
0.35	GO:0070062	extracellular exosome
0.34	GO:0015934	large ribosomal subunit
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:3.6.1.3

GO:0016887

tr|T1G1I9|T1G1I9_HELRO
Uncharacterized protein
Search

0.62	GO:0007219	Notch signaling pathway
0.56	GO:0030154	cell differentiation
0.55	GO:0007275	multicellular organism development
0.53	GO:0050793	regulation of developmental process
0.43	GO:0043547	positive regulation of GTPase activity
0.42	GO:0036211	protein modification process
0.41	GO:0044267	cellular protein metabolic process
0.39	GO:0016310	phosphorylation
0.38	GO:0035556	intracellular signal transduction
0.38	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.55	GO:0005509	calcium ion binding
0.43	GO:0005096	GTPase activator activity
0.41	GO:0004672	protein kinase activity
0.39	GO:0032559	adenyl ribonucleotide binding
0.39	GO:0008144	drug binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0003700	DNA binding transcription factor activity
0.39	GO:0019706	protein-cysteine S-palmitoyltransferase activity
0.37	GO:0002039	p53 binding
0.37	GO:0003950	NAD+ ADP-ribosyltransferase activity

0.35	GO:0005694	chromosome
0.34	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.39

GO:0019706

tr|T1G1J0|T1G1J0_HELRO
Uncharacterized protein
Search

0.44	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.43	GO:0016567	protein ubiquitination
0.35	GO:0006952	defense response
0.34	GO:0045454	cell redox homeostasis

0.46	GO:0016874	ligase activity
0.44	GO:0061630	ubiquitin protein ligase activity
0.41	GO:0008270	zinc ion binding
0.37	GO:0035091	phosphatidylinositol binding
0.33	GO:0016787	hydrolase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003676	nucleic acid binding

0.35	GO:0005680	anaphase-promoting complex
0.30	GO:0016021	integral component of membrane

0.46

GO:0016874

tr|T1G1J1|T1G1J1_HELRO
Uncharacterized protein
Search

0.57	Phosphatidylinositol-binding clathrin assembly protein LAP

0.82	GO:0048268	clathrin coat assembly
0.35	GO:0006897	endocytosis
0.35	GO:0036465	synaptic vesicle recycling
0.35	GO:0099003	vesicle-mediated transport in synapse
0.34	GO:2000370	positive regulation of clathrin-dependent endocytosis
0.34	GO:0042331	phototaxis
0.34	GO:0007268	chemical synaptic transmission
0.34	GO:0097480	establishment of synaptic vesicle localization
0.34	GO:0006420	arginyl-tRNA aminoacylation
0.33	GO:0099643	signal release from synapse

0.84	GO:0005545	1-phosphatidylinositol binding
0.80	GO:0030276	clathrin binding
0.34	GO:0004814	arginine-tRNA ligase activity
0.33	GO:0003779	actin binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.79	GO:0030136	clathrin-coated vesicle
0.34	GO:0045202	synapse
0.34	GO:0005905	clathrin-coated pit
0.33	GO:0005794	Golgi apparatus
0.33	GO:0097458	neuron part
0.30	GO:0016021	integral component of membrane

0.34

EC:6.1.1.19

GO:0004814

tr|T1G1J2|T1G1J2_HELRO
Uncharacterized protein
Search

0.67	SprT domain-containing protein Spartan

0.61	GO:0006974	cellular response to DNA damage stimulus
0.56	GO:0006259	DNA metabolic process
0.53	GO:0009411	response to UV
0.51	GO:0031398	positive regulation of protein ubiquitination
0.41	GO:0051606	detection of stimulus
0.40	GO:0034654	nucleobase-containing compound biosynthetic process
0.39	GO:0009059	macromolecule biosynthetic process
0.38	GO:0000278	mitotic cell cycle
0.37	GO:0006556	S-adenosylmethionine biosynthetic process
0.34	GO:0009187	cyclic nucleotide metabolic process

0.55	GO:0031593	polyubiquitin modification-dependent protein binding
0.52	GO:0003677	DNA binding
0.51	GO:0043130	ubiquitin binding
0.37	GO:0004478	methionine adenosyltransferase activity
0.34	GO:0046872	metal ion binding
0.33	GO:0016849	phosphorus-oxygen lyase activity

0.50	GO:0016607	nuclear speck
0.41	GO:0042585	germinal vesicle
0.41	GO:0001940	male pronucleus
0.36	GO:0005694	chromosome
0.30	GO:0016020	membrane

0.37

EC:2.5.1.6

GO:0004478

tr|T1G1J3|T1G1J3_HELRO
Uncharacterized protein
Search

0.61	Pleckstrin similarity domain protein

0.87	GO:1904259	regulation of basement membrane assembly involved in embryonic body morphogenesis
0.87	GO:1903690	negative regulation of wound healing, spreading of epidermal cells
0.87	GO:1901203	positive regulation of extracellular matrix assembly
0.86	GO:0051497	negative regulation of stress fiber assembly
0.86	GO:0051895	negative regulation of focal adhesion assembly
0.85	GO:0040019	positive regulation of embryonic development
0.85	GO:0010470	regulation of gastrulation
0.85	GO:0010717	regulation of epithelial to mesenchymal transition
0.81	GO:0070507	regulation of microtubule cytoskeleton organization
0.75	GO:0000226	microtubule cytoskeleton organization

0.80

GO:0045296

cadherin binding

0.86	GO:0045180	basal cortex
0.80	GO:0005925	focal adhesion
0.79	GO:0031252	cell leading edge
0.75	GO:0045111	intermediate filament cytoskeleton
0.66	GO:0005829	cytosol
0.54	GO:0005886	plasma membrane

tr|T1G1J4|T1G1J4_HELRO
Uncharacterized protein
Search

NTN1

0.89	Putative extracellular matrix glycoprotein laminin subunit beta (Fragment)

0.56	GO:0050770	regulation of axonogenesis
0.55	GO:0061387	regulation of extent of cell growth
0.55	GO:0007411	axon guidance
0.53	GO:0048638	regulation of developmental growth
0.51	GO:0048513	animal organ development
0.49	GO:0016358	dendrite development
0.49	GO:0021952	central nervous system projection neuron axonogenesis
0.48	GO:0010770	positive regulation of cell morphogenesis involved in differentiation
0.48	GO:0048598	embryonic morphogenesis
0.48	GO:0010976	positive regulation of neuron projection development

0.42	GO:0005102	receptor binding
0.33	GO:0004386	helicase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003676	nucleic acid binding

0.64	GO:0005576	extracellular region
0.42	GO:0005794	Golgi apparatus
0.40	GO:0030424	axon
0.38	GO:0030426	growth cone
0.33	GO:0071944	cell periphery
0.32	GO:0005829	cytosol
0.30	GO:0016020	membrane

tr|T1G1J5|T1G1J5_HELRO
Uncharacterized protein
Search

0.64	Aly/REF export factor 2

0.39	GO:0051028	mRNA transport
0.38	GO:0008380	RNA splicing
0.37	GO:0006397	mRNA processing
0.36	GO:0050790	regulation of catalytic activity
0.36	GO:0046784	viral mRNA export from host cell nucleus
0.35	GO:0001649	osteoblast differentiation
0.35	GO:0031297	replication fork processing
0.35	GO:0032786	positive regulation of DNA-templated transcription, elongation
0.35	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.35	GO:0000018	regulation of DNA recombination

0.59	GO:0003723	RNA binding
0.39	GO:0005094	Rho GDP-dissociation inhibitor activity
0.36	GO:0004306	ethanolamine-phosphate cytidylyltransferase activity
0.35	GO:0070403	NAD+ binding
0.34	GO:0003697	single-stranded DNA binding
0.32	GO:0005515	protein binding

0.46	GO:0016607	nuclear speck
0.39	GO:0031514	motile cilium
0.36	GO:0005681	spliceosomal complex
0.35	GO:0035145	exon-exon junction complex
0.35	GO:0000346	transcription export complex
0.35	GO:0000784	nuclear chromosome, telomeric region
0.35	GO:0070062	extracellular exosome
0.35	GO:0005737	cytoplasm
0.33	GO:1902494	catalytic complex
0.30	GO:0016020	membrane

0.36

EC:2.7.7.14

GO:0004306

tr|T1G1J6|T1G1J6_HELRO
Uncharacterized protein
Search

ANAPC2

0.78	Anaphase-promoting complex subunit

0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.51	GO:0050807	regulation of synapse organization
0.51	GO:0070979	protein K11-linked ubiquitination
0.51	GO:0050804	modulation of chemical synaptic transmission
0.49	GO:0051960	regulation of nervous system development
0.45	GO:0051094	positive regulation of developmental process
0.45	GO:0051240	positive regulation of multicellular organismal process
0.44	GO:0051130	positive regulation of cellular component organization
0.44	GO:0048638	regulation of developmental growth
0.43	GO:0045926	negative regulation of growth

0.79	GO:0031625	ubiquitin protein ligase binding
0.42	GO:0061630	ubiquitin protein ligase activity
0.34	GO:0019902	phosphatase binding

0.52	GO:0005680	anaphase-promoting complex
0.33	GO:0005654	nucleoplasm
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

tr|T1G1J7|T1G1J7_HELRO
Uncharacterized protein
Search

0.63	GO:0006468	protein phosphorylation
0.63	GO:0035556	intracellular signal transduction
0.51	GO:0038033	positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway
0.51	GO:1901727	positive regulation of histone deacetylase activity
0.50	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway
0.50	GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway
0.50	GO:0050862	positive regulation of T cell receptor signaling pathway
0.50	GO:0045765	regulation of angiogenesis
0.50	GO:0032743	positive regulation of interleukin-2 production
0.49	GO:0032793	positive regulation of CREB transcription factor activity

0.84	GO:0004697	protein kinase C activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0046872	metal ion binding
0.49	GO:0005080	protein kinase C binding

0.45	GO:0005622	intracellular
0.43	GO:0031974	membrane-enclosed lumen
0.39	GO:0044422	organelle part
0.39	GO:0043227	membrane-bounded organelle
0.35	GO:0012505	endomembrane system
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.84

EC:2.7.11.13

GO:0004697

tr|T1G1J8|T1G1J8_HELRO
Uncharacterized protein
Search

WARS

0.54	Tryptophanyl-tRNA synthetase

0.78	GO:0006436	tryptophanyl-tRNA aminoacylation
0.47	GO:0010835	regulation of protein ADP-ribosylation
0.44	GO:0045765	regulation of angiogenesis
0.44	GO:0006469	negative regulation of protein kinase activity
0.43	GO:0031334	positive regulation of protein complex assembly
0.42	GO:0010628	positive regulation of gene expression
0.41	GO:0048813	dendrite morphogenesis
0.36	GO:0001525	angiogenesis
0.34	GO:0031204	posttranslational protein targeting to membrane, translocation
0.34	GO:0008285	negative regulation of cell proliferation

0.79	GO:0004830	tryptophan-tRNA ligase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0019210	kinase inhibitor activity
0.43	GO:0019901	protein kinase binding
0.43	GO:0019904	protein domain specific binding
0.42	GO:0046983	protein dimerization activity
0.42	GO:0042802	identical protein binding

0.49	GO:0005737	cytoplasm
0.39	GO:0005634	nucleus
0.38	GO:0043234	protein complex
0.34	GO:0070062	extracellular exosome
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.79

EC:6.1.1.2

GO:0004830

tr|T1G1J9|T1G1J9_HELRO
Uncharacterized protein
Search

tr|T1G1K0|T1G1K0_HELRO
Uncharacterized protein
Search

0.50	GO:0006468	protein phosphorylation
0.47	GO:0006888	ER to Golgi vesicle-mediated transport
0.46	GO:1903288	positive regulation of potassium ion import
0.45	GO:0006396	RNA processing
0.44	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.44	GO:0035220	wing disc development
0.44	GO:0006886	intracellular protein transport
0.43	GO:0007411	axon guidance
0.43	GO:0051568	histone H3-K4 methylation
0.41	GO:0006357	regulation of transcription by RNA polymerase II

0.52	GO:0004674	protein serine/threonine kinase activity
0.44	GO:0032559	adenyl ribonucleotide binding
0.43	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.43	GO:0008144	drug binding
0.43	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0001104	RNA polymerase II transcription cofactor activity
0.40	GO:0046872	metal ion binding
0.40	GO:0046983	protein dimerization activity
0.36	GO:0003677	DNA binding

0.47	GO:0030127	COPII vesicle coat
0.45	GO:0044451	nucleoplasm part
0.42	GO:0034708	methyltransferase complex
0.30	GO:0016021	integral component of membrane

0.52

GO:0004674

tr|T1G1K1|T1G1K1_HELRO
Uncharacterized protein
Search

POC1A

0.96	POC1 centriolar protein like protein A

0.84	GO:0003431	growth plate cartilage chondrocyte development
0.81	GO:0010825	positive regulation of centrosome duplication
0.77	GO:1905515	non-motile cilium assembly
0.75	GO:0007052	mitotic spindle organization
0.73	GO:0007283	spermatogenesis
0.49	GO:0007634	optokinetic behavior
0.49	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry
0.48	GO:0010842	retina layer formation
0.47	GO:0003014	renal system process
0.45	GO:0007507	heart development

0.36	GO:0005515	protein binding
0.33	GO:0003676	nucleic acid binding

0.79	GO:0005814	centriole
0.78	GO:0036064	ciliary basal body
0.74	GO:0000922	spindle pole
0.73	GO:0005813	centrosome

tr|T1G1K2|T1G1K2_HELRO
Uncharacterized protein
Search

tr|T1G1K3|T1G1K3_HELRO
Uncharacterized protein
Search

TMEM145

0.66	Transmembrane protein 145

0.82	GO:0019236	response to pheromone
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.36	GO:0008203	cholesterol metabolic process
0.35	GO:0016042	lipid catabolic process
0.32	GO:0016579	protein deubiquitination
0.32	GO:0006511	ubiquitin-dependent protein catabolic process

0.35	GO:0016298	lipase activity
0.35	GO:0005509	calcium ion binding
0.33	GO:0008270	zinc ion binding
0.32	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.31	GO:0003723	RNA binding

0.30

GO:0031224

intrinsic component of membrane

0.35

EC:3.1.1

GO:0016298

tr|T1G1K4|T1G1K4_HELRO
Uncharacterized protein
Search

tr|T1G1K5|T1G1K5_HELRO
Uncharacterized protein
Search

0.58	Two pore potassium channel protein sup-9 (Fragment)

0.67	GO:0071805	potassium ion transmembrane transport
0.42	GO:0030322	stabilization of membrane potential
0.38	GO:0042321	negative regulation of circadian sleep/wake cycle, sleep
0.38	GO:0045837	negative regulation of membrane potential
0.38	GO:1903351	cellular response to dopamine
0.33	GO:0032259	methylation
0.32	GO:0007018	microtubule-based movement
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.70	GO:0005267	potassium channel activity
0.42	GO:0022842	narrow pore channel activity
0.33	GO:0008168	methyltransferase activity
0.33	GO:0022843	voltage-gated cation channel activity
0.32	GO:0003777	microtubule motor activity
0.32	GO:0008017	microtubule binding
0.31	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.38	GO:0005887	integral component of plasma membrane
0.32	GO:0005634	nucleus

0.33

GO:0008168

tr|T1G1K6|T1G1K6_HELRO
Uncharacterized protein
Search

0.10	Growth factor receptor-bound protein 2 (Fragment)

0.76	GO:0007265	Ras protein signal transduction
0.58	GO:0008286	insulin receptor signaling pathway
0.58	GO:0031623	receptor internalization
0.57	GO:0071479	cellular response to ionizing radiation
0.57	GO:0042770	signal transduction in response to DNA damage
0.57	GO:2000379	positive regulation of reactive oxygen species metabolic process
0.57	GO:0060670	branching involved in labyrinthine layer morphogenesis
0.54	GO:0030838	positive regulation of actin filament polymerization
0.53	GO:0043408	regulation of MAPK cascade
0.52	GO:0009967	positive regulation of signal transduction

0.60	GO:0005168	neurotrophin TRKA receptor binding
0.60	GO:0043560	insulin receptor substrate binding
0.59	GO:0005154	epidermal growth factor receptor binding
0.58	GO:0001784	phosphotyrosine residue binding
0.58	GO:0046875	ephrin receptor binding
0.57	GO:0005070	SH3/SH2 adaptor activity
0.56	GO:0019903	protein phosphatase binding
0.54	GO:0017124	SH3 domain binding
0.53	GO:0019901	protein kinase binding
0.51	GO:0042802	identical protein binding

0.61	GO:0070436	Grb2-EGFR complex
0.55	GO:0008180	COP9 signalosome
0.53	GO:0005768	endosome
0.53	GO:0005911	cell-cell junction
0.52	GO:0012506	vesicle membrane
0.51	GO:0005730	nucleolus
0.50	GO:0005654	nucleoplasm
0.45	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.39	GO:0005794	Golgi apparatus
0.36	GO:0070062	extracellular exosome

0.45	EC:2.7.10.2	GO:0004715
0.35	KEGG:R04545	GO:0046934

tr|T1G1K7|T1G1K7_HELRO
Uncharacterized protein
Search

ATR

0.51	Serine/threonine-protein kinase ATR

0.59	GO:0006468	protein phosphorylation
0.59	GO:1904884	positive regulation of telomerase catalytic core complex assembly
0.59	GO:0097694	establishment of RNA localization to telomere
0.58	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator
0.57	GO:0070198	protein localization to chromosome, telomeric region
0.57	GO:0090399	replicative senescence
0.57	GO:0071480	cellular response to gamma radiation
0.55	GO:0034644	cellular response to UV
0.54	GO:0018209	peptidyl-serine modification
0.53	GO:0008156	negative regulation of DNA replication

0.66	GO:0004674	protein serine/threonine kinase activity
0.59	GO:0032407	MutSalpha complex binding
0.58	GO:0032405	MutLalpha complex binding
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0046982	protein heterodimerization activity
0.34	GO:0003677	DNA binding

0.55	GO:0016605	PML body
0.49	GO:0005794	Golgi apparatus
0.37	GO:0001741	XY body
0.35	GO:0000784	nuclear chromosome, telomeric region
0.33	GO:0055044	symplast
0.33	GO:0005911	cell-cell junction
0.30	GO:0031224	intrinsic component of membrane

0.66

GO:0004674

tr|T1G1K8|T1G1K8_HELRO
Uncharacterized protein
Search

DOLPP1

0.96	Dolichyl pyrophosphate phosphatase 1

0.54	GO:0006487	protein N-linked glycosylation
0.41	GO:0008610	lipid biosynthetic process
0.35	GO:0098869	cellular oxidant detoxification
0.35	GO:0046465	dolichyl diphosphate metabolic process
0.34	GO:0006488	dolichol-linked oligosaccharide biosynthetic process
0.34	GO:0008053	mitochondrial fusion
0.33	GO:0090407	organophosphate biosynthetic process
0.33	GO:0006749	glutathione metabolic process
0.32	GO:0045454	cell redox homeostasis
0.32	GO:0055114	oxidation-reduction process

0.61	GO:0047874	dolichyldiphosphatase activity
0.36	GO:0016209	antioxidant activity
0.35	GO:0016684	oxidoreductase activity, acting on peroxide as acceptor
0.33	GO:0015038	glutathione disulfide oxidoreductase activity
0.33	GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor
0.32	GO:0050661	NADP binding
0.32	GO:0050660	flavin adenine dinucleotide binding

0.52

GO:0030176

integral component of endoplasmic reticulum membrane

0.61

EC:3.6.1.43

GO:0047874

tr|T1G1K9|T1G1K9_HELRO
DNA-directed RNA polymerase subunit
Search

ZNRD1

0.45	DNA-directed RNA polymerase subunit

0.80	GO:0006379	mRNA cleavage
0.58	GO:0006351	transcription, DNA-templated
0.37	GO:0040029	regulation of gene expression, epigenetic
0.36	GO:0051172	negative regulation of nitrogen compound metabolic process
0.36	GO:0031324	negative regulation of cellular metabolic process
0.36	GO:0010605	negative regulation of macromolecule metabolic process
0.36	GO:0009890	negative regulation of biosynthetic process
0.34	GO:0080090	regulation of primary metabolic process
0.34	GO:0016072	rRNA metabolic process
0.34	GO:0006325	chromatin organization

0.70	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.63	GO:0008270	zinc ion binding
0.51	GO:0003676	nucleic acid binding
0.37	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding
0.35	GO:0004865	protein serine/threonine phosphatase inhibitor activity

0.71	GO:0005730	nucleolus
0.47	GO:0055029	nuclear DNA-directed RNA polymerase complex
0.35	GO:0005654	nucleoplasm

0.70

GO:0003899

tr|T1G1L0|T1G1L0_HELRO
Uncharacterized protein
Search

METTL9

0.96	Methyltransferase like 9

0.60	GO:0032259	methylation
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:2001141	regulation of RNA biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.60	GO:0008168	methyltransferase activity
0.35	GO:0030554	adenyl nucleotide binding
0.34	GO:0097367	carbohydrate derivative binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005515	protein binding
0.33	GO:0003676	nucleic acid binding

0.33	GO:0005634	nucleus
0.30	GO:0044425	membrane part

0.60

GO:0008168

tr|T1G1L1|T1G1L1_HELRO
Uncharacterized protein
Search

0.53	Polynucleotide adenylyltransferase PAP1

0.80	GO:0043631	RNA polyadenylation
0.76	GO:0031123	RNA 3'-end processing
0.58	GO:0033621	nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts
0.56	GO:0043144	snoRNA processing
0.50	GO:0006397	mRNA processing
0.33	GO:0071450	cellular response to oxygen radical
0.33	GO:0000303	response to superoxide
0.33	GO:0006801	superoxide metabolic process
0.33	GO:0098869	cellular oxidant detoxification
0.32	GO:0055114	oxidation-reduction process

0.78	GO:0004652	polynucleotide adenylyltransferase activity
0.59	GO:0003723	RNA binding
0.49	GO:0032559	adenyl ribonucleotide binding
0.48	GO:0046872	metal ion binding
0.48	GO:0008144	drug binding
0.48	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0004784	superoxide dismutase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0032561	guanyl ribonucleotide binding

0.61	GO:0005634	nucleus
0.49	GO:0005829	cytosol
0.48	GO:0031974	membrane-enclosed lumen
0.44	GO:0043234	protein complex
0.43	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.78

EC:2.7.7.19

GO:0004652

tr|T1G1L2|T1G1L2_HELRO
Uncharacterized protein
Search

0.63	GO:0006468	protein phosphorylation
0.41	GO:0018209	peptidyl-serine modification
0.40	GO:0018210	peptidyl-threonine modification
0.39	GO:0007165	signal transduction
0.37	GO:0030010	establishment of cell polarity
0.36	GO:0000226	microtubule cytoskeleton organization
0.35	GO:0051726	regulation of cell cycle
0.34	GO:0032147	activation of protein kinase activity
0.34	GO:0007049	cell cycle
0.34	GO:0005978	glycogen biosynthetic process

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0005509	calcium ion binding
0.36	GO:0005516	calmodulin binding
0.34	GO:0003774	motor activity
0.33	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.33	GO:0060089	molecular transducer activity
0.32	GO:0000287	magnesium ion binding

0.36	GO:0005634	nucleus
0.34	GO:0016459	myosin complex
0.34	GO:0005964	phosphorylase kinase complex
0.30	GO:0016020	membrane

0.33

GO:0003950

tr|T1G1L3|T1G1L3_HELRO
Uncharacterized protein
Search

0.39	GO:0035118	embryonic pectoral fin morphogenesis
0.38	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:0051569	regulation of histone H3-K4 methylation
0.36	GO:0010468	regulation of gene expression
0.36	GO:0007020	microtubule nucleation
0.35	GO:0030097	hemopoiesis
0.32	GO:0006351	transcription, DNA-templated

0.51	GO:0003676	nucleic acid binding
0.39	GO:0008270	zinc ion binding
0.36	GO:0043015	gamma-tubulin binding
0.35	GO:0003700	DNA binding transcription factor activity

0.39	GO:0005634	nucleus
0.36	GO:0000922	spindle pole
0.35	GO:0005815	microtubule organizing center
0.34	GO:0043233	organelle lumen

tr|T1G1L4|T1G1L4_HELRO
Anoctamin
Search

0.36

Anoctamin

0.72

GO:0061588

calcium activated phospholipid scrambling

0.64	GO:0046983	protein dimerization activity
0.45	GO:0017128	phospholipid scramblase activity

0.30

GO:0044425

membrane part

tr|T1G1L5|T1G1L5_HELRO
Uncharacterized protein
Search

tr|T1G1L6|T1G1L6_HELRO
Uncharacterized protein
Search

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.37	GO:0018108	peptidyl-tyrosine phosphorylation
0.37	GO:0007631	feeding behavior
0.34	GO:0009116	nucleoside metabolic process
0.34	GO:0007166	cell surface receptor signaling pathway
0.34	GO:0009165	nucleotide biosynthetic process

0.72	GO:0004930	G-protein coupled receptor activity
0.67	GO:0001653	peptide receptor activity
0.39	GO:0030594	neurotransmitter receptor activity
0.38	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.37	GO:0050254	rhodopsin kinase activity
0.35	GO:0004749	ribose phosphate diphosphokinase activity
0.34	GO:0000287	magnesium ion binding

0.37

GO:0005887

integral component of plasma membrane

0.38	EC:2.7.10.2	GO:0004715
0.35	KEGG:R01049	GO:0004749

tr|T1G1L7|T1G1L7_HELRO
Coronin
Search

0.67

Coronin

0.70	GO:0030036	actin cytoskeleton organization
0.61	GO:0016477	cell migration
0.59	GO:0001845	phagolysosome assembly
0.57	GO:2000394	positive regulation of lamellipodium morphogenesis
0.57	GO:0030334	regulation of cell migration
0.57	GO:0044387	negative regulation of protein kinase activity by regulation of protein phosphorylation
0.56	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading
0.56	GO:0051895	negative regulation of focal adhesion assembly
0.56	GO:1900027	regulation of ruffle assembly
0.55	GO:0014032	neural crest cell development

0.76	GO:0051015	actin filament binding
0.55	GO:0048365	Rac GTPase binding
0.51	GO:0032036	myosin heavy chain binding
0.50	GO:0043548	phosphatidylinositol 3-kinase binding
0.49	GO:0003785	actin monomer binding
0.48	GO:0008022	protein C-terminus binding
0.46	GO:0042803	protein homodimerization activity

0.70	GO:0015629	actin cytoskeleton
0.59	GO:0030027	lamellipodium
0.57	GO:0016600	flotillin complex
0.55	GO:0016328	lateral plasma membrane
0.54	GO:0031982	vesicle
0.50	GO:0001891	phagocytic cup
0.50	GO:0001772	immunological synapse
0.47	GO:0030863	cortical cytoskeleton
0.47	GO:0030424	axon
0.46	GO:0005911	cell-cell junction

tr|T1G1L8|T1G1L8_HELRO
Uncharacterized protein
Search

NCS1

0.84	Neuronal calcium sensor 1 (inferred by orthology to a human protein)

0.46	GO:1905949	negative regulation of calcium ion import across plasma membrane
0.46	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.43	GO:0042327	positive regulation of phosphorylation
0.40	GO:0048731	system development
0.39	GO:0120035	regulation of plasma membrane bounded cell projection organization
0.39	GO:0051960	regulation of nervous system development
0.39	GO:0060284	regulation of cell development
0.39	GO:0043085	positive regulation of catalytic activity
0.39	GO:0023051	regulation of signaling
0.39	GO:0010646	regulation of cell communication

0.70	GO:0005509	calcium ion binding
0.47	GO:0098744	1-phosphatidylinositol 4-kinase activator activity
0.39	GO:0005245	voltage-gated calcium channel activity
0.37	GO:0019901	protein kinase binding
0.35	GO:0000287	magnesium ion binding
0.35	GO:0008427	calcium-dependent protein kinase inhibitor activity
0.34	GO:0008092	cytoskeletal protein binding
0.34	GO:0004784	superoxide dismutase activity
0.33	GO:0003777	microtubule motor activity
0.33	GO:0042802	identical protein binding

0.48	GO:0030425	dendrite
0.48	GO:0030424	axon
0.42	GO:0005886	plasma membrane
0.41	GO:0043231	intracellular membrane-bounded organelle
0.40	GO:0012505	endomembrane system
0.39	GO:0014069	postsynaptic density
0.39	GO:0005737	cytoplasm
0.38	GO:0098588	bounding membrane of organelle
0.38	GO:0031984	organelle subcompartment
0.37	GO:0030054	cell junction

0.34

EC:1.15.1.1

GO:0004784

tr|T1G1L9|T1G1L9_HELRO
Uncharacterized protein
Search

CCDC65

0.77	Coiled-coil domain-containing protein 65

0.85	GO:0003352	regulation of cilium movement
0.77	GO:0060271	cilium assembly
0.36	GO:0000278	mitotic cell cycle
0.35	GO:0051301	cell division

0.42	GO:0003779	actin binding
0.40	GO:0008270	zinc ion binding

tr|T1G1M0|T1G1M0_HELRO
Uncharacterized protein
Search

0.75	von Willebrand factor A domain-containing protein 5A

0.44	GO:0016192	vesicle-mediated transport
0.43	GO:0006334	nucleosome assembly
0.38	GO:0006606	protein import into nucleus
0.38	GO:0006366	transcription by RNA polymerase II
0.37	GO:0018108	peptidyl-tyrosine phosphorylation
0.35	GO:0030212	hyaluronan metabolic process
0.34	GO:0010951	negative regulation of endopeptidase activity

0.38	GO:0061608	nuclear import signal receptor activity
0.38	GO:0003677	DNA binding
0.37	GO:0004713	protein tyrosine kinase activity
0.35	GO:0008270	zinc ion binding
0.35	GO:0004867	serine-type endopeptidase inhibitor activity

0.53	GO:0005654	nucleoplasm
0.42	GO:0000786	nucleosome
0.38	GO:0005576	extracellular region
0.38	GO:0055029	nuclear DNA-directed RNA polymerase complex
0.30	GO:0031224	intrinsic component of membrane

0.37

GO:0004713

tr|T1G1M1|T1G1M1_HELRO
Uncharacterized protein
Search

CHID1

0.85	Chitinase domain-containing protein 1

0.59	GO:0005975	carbohydrate metabolic process
0.43	GO:0006032	chitin catabolic process
0.40	GO:1900016	negative regulation of cytokine production involved in inflammatory response
0.38	GO:0006954	inflammatory response
0.32	GO:0071897	DNA biosynthetic process
0.32	GO:0006260	DNA replication

0.75	GO:0008061	chitin binding
0.45	GO:0004568	chitinase activity
0.39	GO:0070492	oligosaccharide binding
0.33	GO:0016853	isomerase activity
0.33	GO:0003887	DNA-directed DNA polymerase activity
0.32	GO:0003677	DNA binding
0.32	GO:1901265	nucleoside phosphate binding
0.32	GO:0036094	small molecule binding

0.41	GO:0005576	extracellular region
0.40	GO:0005764	lysosome
0.38	GO:0005770	late endosome
0.38	GO:0005802	trans-Golgi network
0.35	GO:0005783	endoplasmic reticulum
0.30	GO:0031224	intrinsic component of membrane

0.45

EC:3.2.1.14

GO:0004568

tr|T1G1M2|T1G1M2_HELRO
Uncharacterized protein
Search

0.25	DNA replication licensing factor, MCM2 component

0.75	GO:0006270	DNA replication initiation
0.51	GO:0000724	double-strand break repair via homologous recombination
0.50	GO:0007292	female gamete generation
0.34	GO:0008380	RNA splicing

0.55	GO:0032559	adenyl ribonucleotide binding
0.55	GO:0003677	DNA binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0004386	helicase activity
0.33	GO:0005515	protein binding

0.59	GO:0097362	MCM8-MCM9 complex
0.38	GO:0005634	nucleus
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

tr|T1G1M3|T1G1M3_HELRO
Uncharacterized protein
Search

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.40	GO:0048663	neuron fate commitment
0.39	GO:0007411	axon guidance
0.36	GO:0021515	cell differentiation in spinal cord
0.35	GO:0060573	cell fate specification involved in pattern specification
0.34	GO:0021513	spinal cord dorsal/ventral patterning
0.34	GO:0021517	ventral spinal cord development
0.34	GO:0021953	central nervous system neuron differentiation

0.64

GO:0043565

sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|T1G1M4|T1G1M4_HELRO
Uncharacterized protein
Search

0.47	GO:0061158	3'-UTR-mediated mRNA destabilization
0.43	GO:1900153	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
0.43	GO:0016246	RNA interference
0.38	GO:0097403	cellular response to raffinose
0.38	GO:1904582	positive regulation of intracellular mRNA localization
0.38	GO:0003343	septum transversum development
0.38	GO:1902172	regulation of keratinocyte apoptotic process
0.38	GO:0060710	chorio-allantoic fusion
0.38	GO:0038066	p38MAPK cascade
0.38	GO:0045657	positive regulation of monocyte differentiation

0.54	GO:0046872	metal ion binding
0.46	GO:0003730	mRNA 3'-UTR binding
0.45	GO:0017091	AU-rich element binding
0.38	GO:0071889	14-3-3 protein binding
0.33	GO:0003677	DNA binding

0.37	GO:0005829	cytosol
0.37	GO:0000932	P-body
0.35	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|T1G1M5|T1G1M5_HELRO
Uncharacterized protein
Search

0.40	Transmembrane and TPR repeat-containing protein 1

0.81	GO:0042073	intraciliary transport
0.76	GO:0060271	cilium assembly
0.62	GO:0036372	opsin transport
0.61	GO:0018095	protein polyglutamylation
0.57	GO:0001736	establishment of planar polarity
0.56	GO:0007368	determination of left/right symmetry
0.36	GO:0007165	signal transduction

0.64	GO:0070738	tubulin-glycine ligase activity
0.45	GO:0005215	transporter activity
0.39	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.36	GO:0005515	protein binding
0.34	GO:0046872	metal ion binding

0.75	GO:0030992	intraciliary transport particle B
0.74	GO:0005929	cilium
0.60	GO:0005881	cytoplasmic microtubule
0.58	GO:0032838	plasma membrane bounded cell projection cytoplasm
0.43	GO:0005815	microtubule organizing center
0.30	GO:0031224	intrinsic component of membrane

0.64

EC:6.3.2

GO:0070738

tr|T1G1M6|T1G1M6_HELRO
Uncharacterized protein
Search

0.67	GO:0009967	positive regulation of signal transduction
0.55	GO:0007165	signal transduction
0.44	GO:0006915	apoptotic process
0.39	GO:0006413	translational initiation
0.37	GO:0070932	histone H3 deacetylation
0.36	GO:0016310	phosphorylation
0.34	GO:0006351	transcription, DNA-templated
0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression

0.75	GO:0005070	SH3/SH2 adaptor activity
0.39	GO:0003743	translation initiation factor activity
0.38	GO:0016630	protochlorophyllide reductase activity
0.37	GO:0032041	NAD-dependent histone deacetylase activity (H3-K14 specific)
0.37	GO:0016301	kinase activity

0.34	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.38

EC:1.3.1.33

GO:0016630

tr|T1G1M7|T1G1M7_HELRO
Uncharacterized protein
Search

tr|T1G1M8|T1G1M8_HELRO
Uncharacterized protein
Search

0.54	52 kDa repressor of the inhibitor of the protein kinase

0.56

GO:0016310

phosphorylation

0.68	GO:0046983	protein dimerization activity
0.59	GO:0016301	kinase activity

tr|T1G1M9|T1G1M9_HELRO
Uncharacterized protein
Search

0.60	Proprotein convertase subtilisin/kexin type 1

0.61	GO:0006508	proteolysis
0.36	GO:0008038	neuron recognition
0.36	GO:0097688	glutamate receptor clustering
0.36	GO:0097090	presynaptic membrane organization
0.36	GO:0051604	protein maturation
0.36	GO:0001941	postsynaptic membrane organization
0.35	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.35	GO:0018108	peptidyl-tyrosine phosphorylation
0.34	GO:1905910	negative regulation of dauer entry
0.34	GO:0042445	hormone metabolic process

0.69	GO:0004252	serine-type endopeptidase activity
0.35	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.34	GO:0005509	calcium ion binding
0.33	GO:0005515	protein binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0008237	metallopeptidase activity
0.32	GO:0008270	zinc ion binding
0.32	GO:0016491	oxidoreductase activity

0.35	GO:0005615	extracellular space
0.35	GO:0098791	Golgi subcompartment
0.34	GO:0098588	bounding membrane of organelle
0.34	GO:0043025	neuronal cell body
0.33	GO:0001669	acrosomal vesicle
0.33	GO:0030659	cytoplasmic vesicle membrane
0.33	GO:0005886	plasma membrane
0.32	GO:0098805	whole membrane
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0004252

tr|T1G1N0|T1G1N0_HELRO
Uncharacterized protein
Search

0.74	Serine threonine-protein kinase unc-51 (Fragment)

0.63	GO:0006468	protein phosphorylation
0.38	GO:0045138	nematode male tail tip morphogenesis
0.38	GO:0040024	dauer larval development
0.38	GO:0043277	apoptotic cell clearance
0.38	GO:0030516	regulation of axon extension
0.38	GO:0040014	regulation of multicellular organism growth
0.38	GO:0008340	determination of adult lifespan
0.37	GO:0007411	axon guidance
0.37	GO:0009792	embryo development ending in birth or egg hatching
0.37	GO:0016477	cell migration

0.67	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.37	GO:0043025	neuronal cell body
0.37	GO:0030424	axon
0.31	GO:0005622	intracellular
0.30	GO:0016020	membrane

0.67

GO:0004674

tr|T1G1N1|T1G1N1_HELRO
Uncharacterized protein
Search

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.44	GO:0007166	cell surface receptor signaling pathway
0.44	GO:0007186	G-protein coupled receptor signaling pathway
0.41	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.40	GO:0007267	cell-cell signaling
0.40	GO:0007399	nervous system development
0.38	GO:0016477	cell migration
0.38	GO:1902358	sulfate transmembrane transport
0.37	GO:0090132	epithelium migration
0.37	GO:0090175	regulation of establishment of planar polarity

0.70	GO:0005509	calcium ion binding
0.44	GO:0004930	G-protein coupled receptor activity
0.38	GO:0015116	sulfate transmembrane transporter activity
0.36	GO:0015291	secondary active transmembrane transporter activity
0.34	GO:0005515	protein binding
0.30	GO:0003824	catalytic activity

0.56	GO:0005886	plasma membrane
0.37	GO:0005913	cell-cell adherens junction
0.34	GO:0089717	spanning component of membrane
0.34	GO:0070062	extracellular exosome
0.34	GO:0005902	microvillus
0.34	GO:0005903	brush border
0.34	GO:0045177	apical part of cell
0.33	GO:0120038	plasma membrane bounded cell projection part

tr|T1G1N2|T1G1N2_HELRO
Uncharacterized protein
Search

0.59	mitogen-activated protein kinase kinase kinase 3-like

0.61	GO:0006468	protein phosphorylation
0.55	GO:0071864	positive regulation of cell proliferation in bone marrow
0.54	GO:2000773	negative regulation of cellular senescence
0.54	GO:1900745	positive regulation of p38MAPK cascade
0.54	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis
0.52	GO:0072359	circulatory system development
0.52	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.46	GO:0031098	stress-activated protein kinase signaling cascade
0.45	GO:0032147	activation of protein kinase activity
0.44	GO:0007346	regulation of mitotic cell cycle

0.62	GO:0004672	protein kinase activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0019901	protein kinase binding
0.35	GO:0005057	signal transducer activity, downstream of receptor
0.33	GO:0046872	metal ion binding

0.39	GO:0005829	cytosol
0.39	GO:0005654	nucleoplasm

tr|T1G1N3|T1G1N3_HELRO
Uncharacterized protein
Search

0.10	Collagen triple helix repeat protein (Fragment)

0.48	GO:0071230	cellular response to amino acid stimulus
0.48	GO:0030198	extracellular matrix organization
0.47	GO:1903225	negative regulation of endodermal cell differentiation
0.46	GO:0001654	eye development
0.45	GO:0009653	anatomical structure morphogenesis
0.45	GO:0043588	skin development
0.44	GO:0001501	skeletal system development
0.42	GO:0097435	supramolecular fiber organization
0.41	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.41	GO:0071822	protein complex subunit organization

0.66	GO:0005201	extracellular matrix structural constituent
0.45	GO:0046332	SMAD binding
0.41	GO:0048407	platelet-derived growth factor binding
0.41	GO:0005044	scavenger receptor activity
0.41	GO:0042302	structural constituent of cuticle
0.38	GO:0005102	receptor binding
0.36	GO:0004867	serine-type endopeptidase inhibitor activity
0.36	GO:0005509	calcium ion binding
0.36	GO:0050839	cell adhesion molecule binding
0.35	GO:0008201	heparin binding

0.67	GO:0005581	collagen trimer
0.57	GO:0044420	extracellular matrix component
0.54	GO:0005578	proteinaceous extracellular matrix
0.45	GO:0099081	supramolecular polymer
0.44	GO:0005615	extracellular space
0.35	GO:0005788	endoplasmic reticulum lumen
0.33	GO:0031594	neuromuscular junction
0.33	GO:0030666	endocytic vesicle membrane
0.32	GO:0005887	integral component of plasma membrane
0.32	GO:0016607	nuclear speck

0.32

EC:5.4.99.12

GO:0009982

tr|T1G1N4|T1G1N4_HELRO
Uncharacterized protein
Search

0.53	Glutamate receptor, ionotropic, AMPA 4b

0.79	GO:0060079	excitatory postsynaptic potential
0.77	GO:0035235	ionotropic glutamate receptor signaling pathway
0.59	GO:0034220	ion transmembrane transport
0.59	GO:0048899	anterior lateral line development
0.57	GO:0048915	posterior lateral line system development
0.55	GO:0014032	neural crest cell development
0.55	GO:0048701	embryonic cranial skeleton morphogenesis
0.50	GO:0007399	nervous system development

0.82	GO:0005234	extracellularly glutamate-gated ion channel activity
0.77	GO:0004970	ionotropic glutamate receptor activity
0.43	GO:0099094	ligand-gated cation channel activity

0.79	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.44	GO:0032281	AMPA glutamate receptor complex

tr|T1G1N5|T1G1N5_HELRO
Uncharacterized protein
Search

TTLL10

0.66	Tubulin tyrosine ligase like 10

0.60

GO:0006464

cellular protein modification process

0.42	GO:0016874	ligase activity
0.41	GO:0030554	adenyl nucleotide binding
0.41	GO:0032555	purine ribonucleotide binding
0.41	GO:0008144	drug binding
0.41	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0140096	catalytic activity, acting on a protein
0.32	GO:0003677	DNA binding

0.35	GO:0019013	viral nucleocapsid
0.34	GO:1990904	ribonucleoprotein complex
0.32	GO:0044424	intracellular part
0.30	GO:0031224	intrinsic component of membrane

0.42

GO:0016874

tr|T1G1N6|T1G1N6_HELRO
Putative lipoyltransferase 2, mitochondrial
Search

0.93	Lipoyltransferase 2 mitochondrial (Fragment)

0.77	GO:0009249	protein lipoylation
0.37	GO:2000376	positive regulation of oxygen metabolic process
0.35	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.34	GO:0070932	histone H3 deacetylation
0.34	GO:0060271	cilium assembly
0.32	GO:0006351	transcription, DNA-templated
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:0010468	regulation of gene expression

0.80	GO:0033819	lipoyl(octanoyl) transferase activity
0.75	GO:0102555	octanoyl transferase activity (acting on glycine-cleavage complex H protein)
0.38	GO:0016874	ligase activity
0.36	GO:0008408	3'-5' exonuclease activity
0.34	GO:0032041	NAD-dependent histone deacetylase activity (H3-K14 specific)
0.33	GO:0003676	nucleic acid binding
0.33	GO:0008270	zinc ion binding

0.57	GO:0005739	mitochondrion
0.34	GO:0005813	centrosome
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.80

EC:2.3.1.181

GO:0033819

tr|T1G1N7|T1G1N7_HELRO
Uncharacterized protein
Search

0.77	Centrosomal protein of 164 kDa (Fragment)

0.79	GO:0060271	cilium assembly
0.44	GO:0051301	cell division
0.43	GO:0007049	cell cycle
0.43	GO:0006281	DNA repair

0.42

GO:0005515

protein binding

0.86	GO:0097539	ciliary transition fiber
0.83	GO:0005814	centriole
0.78	GO:0005813	centrosome
0.67	GO:0005654	nucleoplasm
0.52	GO:0005615	extracellular space

tr|T1G1N8|T1G1N8_HELRO
Ribulose-phosphate 3-epimerase
Search

RPE

0.42	Ribulose-phosphate 3-epimerase

0.70	GO:0006098	pentose-phosphate shunt
0.60	GO:0005975	carbohydrate metabolic process
0.38	GO:0044282	small molecule catabolic process
0.37	GO:1901575	organic substance catabolic process
0.34	GO:0060271	cilium assembly
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.77	GO:0004750	ribulose-phosphate 3-epimerase activity
0.52	GO:0046872	metal ion binding
0.36	GO:0019706	protein-cysteine S-palmitoyltransferase activity
0.34	GO:0030159	receptor signaling complex scaffold activity
0.33	GO:0003700	DNA binding transcription factor activity

0.38	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.77	EC:5.1.3.1	GO:0004750
0.77	KEGG:R01529	GO:0004750

tr|T1G1N9|T1G1N9_HELRO
Uncharacterized protein
Search

0.48	GO:1903225	negative regulation of endodermal cell differentiation
0.47	GO:0071230	cellular response to amino acid stimulus
0.47	GO:0030198	extracellular matrix organization
0.45	GO:0043588	skin development
0.45	GO:0009653	anatomical structure morphogenesis
0.45	GO:0001654	eye development
0.44	GO:0001501	skeletal system development
0.42	GO:0097435	supramolecular fiber organization
0.41	GO:0071822	protein complex subunit organization
0.40	GO:0010951	negative regulation of endopeptidase activity

0.73	GO:0005201	extracellular matrix structural constituent
0.45	GO:0046332	SMAD binding
0.40	GO:0004867	serine-type endopeptidase inhibitor activity
0.40	GO:0042302	structural constituent of cuticle
0.36	GO:0048407	platelet-derived growth factor binding
0.34	GO:0042802	identical protein binding
0.34	GO:0043394	proteoglycan binding
0.33	GO:0008201	heparin binding
0.33	GO:0005178	integrin binding
0.33	GO:0004175	endopeptidase activity

0.65	GO:0005581	collagen trimer
0.56	GO:0044420	extracellular matrix component
0.53	GO:0005578	proteinaceous extracellular matrix
0.44	GO:0099081	supramolecular polymer
0.43	GO:0005615	extracellular space
0.35	GO:0005788	endoplasmic reticulum lumen
0.34	GO:0031594	neuromuscular junction
0.32	GO:0005694	chromosome
0.32	GO:0009360	DNA polymerase III complex
0.30	GO:0016020	membrane

0.32

EC:2.7.7.7

GO:0003887

tr|T1G1P0|T1G1P0_HELRO
Uncharacterized protein
Search

0.11	General transcription factor II-I repeat domain-containing protein 2

0.48	GO:0006351	transcription, DNA-templated
0.48	GO:2001141	regulation of RNA biosynthetic process
0.48	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.48	GO:0014883	transition between fast and slow fiber
0.47	GO:0010468	regulation of gene expression
0.44	GO:0007275	multicellular organism development

0.59	GO:0046983	protein dimerization activity
0.46	GO:0003677	DNA binding
0.45	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding

0.51	GO:0005634	nucleus
0.43	GO:0031974	membrane-enclosed lumen
0.40	GO:0044446	intracellular organelle part
0.37	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1G1P1|T1G1P1_HELRO
Uncharacterized protein
Search

0.77	GO:0016055	Wnt signaling pathway
0.41	GO:0043547	positive regulation of GTPase activity
0.35	GO:0007186	G-protein coupled receptor signaling pathway

0.60	GO:0030159	receptor signaling complex scaffold activity
0.41	GO:0005096	GTPase activator activity
0.36	GO:0001965	G-protein alpha-subunit binding
0.36	GO:0005092	GDP-dissociation inhibitor activity

0.61	GO:0030877	beta-catenin destruction complex
0.36	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1G1P2|T1G1P2_HELRO
Uncharacterized protein
Search

DTWD2

0.43	DTW domain-containing protein 2

0.70	GO:0061053	somite development
0.66	GO:1903955	positive regulation of protein targeting to mitochondrion

0.36

GO:0003677

DNA binding

tr|T1G1P3|T1G1P3_HELRO
Uncharacterized protein
Search

0.85	RNA polymerase II subunit L

0.58	GO:0006351	transcription, DNA-templated
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process

0.70	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.63	GO:0008270	zinc ion binding
0.55	GO:0003677	DNA binding
0.38	GO:0051087	chaperone binding
0.33	GO:0003735	structural constituent of ribosome

0.47	GO:0005665	DNA-directed RNA polymerase II, core complex
0.44	GO:0005736	DNA-directed RNA polymerase I complex
0.44	GO:0005666	DNA-directed RNA polymerase III complex
0.36	GO:0000418	DNA-directed RNA polymerase IV complex
0.36	GO:0000419	DNA-directed RNA polymerase V complex
0.34	GO:0022625	cytosolic large ribosomal subunit
0.30	GO:0016020	membrane

0.70

GO:0003899

tr|T1G1P4|T1G1P4_HELRO
Uncharacterized protein
Search

0.38	Mitochondrial import inner membrane translocase subunit TIM14, putative

0.41	GO:0015031	protein transport
0.37	GO:0032781	positive regulation of ATPase activity
0.37	GO:1990542	mitochondrial transmembrane transport
0.36	GO:0072655	establishment of protein localization to mitochondrion
0.36	GO:0007005	mitochondrion organization
0.35	GO:0046907	intracellular transport
0.34	GO:0006508	proteolysis

0.42	GO:0008566	mitochondrial protein-transporting ATPase activity
0.37	GO:0001671	ATPase activator activity
0.35	GO:0008237	metallopeptidase activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0016874	ligase activity
0.34	GO:0008270	zinc ion binding

0.38	GO:0031966	mitochondrial membrane
0.38	GO:0019866	organelle inner membrane
0.36	GO:0098798	mitochondrial protein complex
0.34	GO:0098796	membrane protein complex
0.30	GO:0031224	intrinsic component of membrane

0.42

EC:3.6.3.51

GO:0008566

tr|T1G1P5|T1G1P5_HELRO
Uncharacterized protein
Search

0.76	GO:0010923	negative regulation of phosphatase activity
0.43	GO:1903506	regulation of nucleic acid-templated transcription
0.43	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.42	GO:0010468	regulation of gene expression

0.47	GO:0001883	purine nucleoside binding
0.46	GO:0019001	guanyl nucleotide binding
0.46	GO:0032549	ribonucleoside binding
0.45	GO:0003700	DNA binding transcription factor activity
0.41	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0032555	purine ribonucleotide binding

tr|T1G1P6|T1G1P6_HELRO
Uncharacterized protein
Search

0.61	GO:0045995	regulation of embryonic development
0.59	GO:0040012	regulation of locomotion
0.58	GO:0007155	cell adhesion
0.58	GO:0051270	regulation of cellular component movement
0.56	GO:0030155	regulation of cell adhesion
0.48	GO:0000904	cell morphogenesis involved in differentiation
0.48	GO:0022008	neurogenesis
0.46	GO:0035001	dorsal trunk growth, open tracheal system
0.46	GO:0048513	animal organ development
0.46	GO:0035011	melanotic encapsulation of foreign target

0.54	GO:0005102	receptor binding
0.48	GO:0005509	calcium ion binding
0.45	GO:0043236	laminin binding
0.36	GO:0035374	chondroitin sulfate binding
0.35	GO:0033691	sialic acid binding
0.35	GO:0002162	dystroglycan binding
0.35	GO:0043395	heparan sulfate proteoglycan binding
0.35	GO:0098772	molecular function regulator
0.34	GO:0017022	myosin binding
0.34	GO:0005518	collagen binding

0.52	GO:0005604	basement membrane
0.46	GO:0036062	presynaptic periactive zone
0.40	GO:0042383	sarcolemma
0.39	GO:0005615	extracellular space
0.36	GO:0043005	neuron projection
0.36	GO:0005829	cytosol
0.35	GO:0030054	cell junction
0.35	GO:0031982	vesicle
0.35	GO:0120038	plasma membrane bounded cell projection part
0.35	GO:0002142	stereocilia ankle link complex

0.34

EC:2.7.10.1

GO:0004714

tr|T1G1P7|T1G1P7_HELRO
Uncharacterized protein
Search

GLA

0.69	Alpha-N-acetylgalactosaminidase

0.60	GO:0005975	carbohydrate metabolic process
0.48	GO:0016139	glycoside catabolic process
0.47	GO:0019377	glycolipid catabolic process
0.46	GO:0006677	glycosylceramide metabolic process
0.46	GO:0046514	ceramide catabolic process
0.37	GO:0051001	negative regulation of nitric-oxide synthase activity
0.37	GO:0045019	negative regulation of nitric oxide biosynthetic process
0.36	GO:0030282	bone mineralization
0.33	GO:0009057	macromolecule catabolic process
0.33	GO:0048870	cell motility

0.66	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.44	GO:0042803	protein homodimerization activity
0.42	GO:0005102	receptor binding
0.37	GO:0016936	galactoside binding
0.35	GO:0030246	carbohydrate binding
0.33	GO:0005509	calcium ion binding

0.44	GO:0005764	lysosome
0.42	GO:0005794	Golgi apparatus
0.40	GO:0005576	extracellular region
0.34	GO:0031514	motile cilium
0.33	GO:0031982	vesicle
0.30	GO:0016020	membrane

0.66

GO:0004553

tr|T1G1P8|T1G1P8_HELRO
Uncharacterized protein
Search

0.54	Adenosine receptor A1

0.78	GO:0001973	adenosine receptor signaling pathway
0.53	GO:0002880	regulation of chronic inflammatory response to non-antigenic stimulus
0.51	GO:0002678	positive regulation of chronic inflammatory response
0.51	GO:0060087	relaxation of vascular smooth muscle
0.51	GO:0033008	positive regulation of mast cell activation involved in immune response
0.50	GO:0043302	positive regulation of leukocyte degranulation
0.50	GO:0002888	positive regulation of myeloid leukocyte mediated immunity
0.50	GO:0031284	positive regulation of guanylate cyclase activity
0.50	GO:0043304	regulation of mast cell degranulation
0.50	GO:0010575	positive regulation of vascular endothelial growth factor production

0.78	GO:0001609	G-protein coupled adenosine receptor activity
0.37	GO:0030594	neurotransmitter receptor activity
0.36	GO:0042802	identical protein binding
0.36	GO:0008227	G-protein coupled amine receptor activity
0.36	GO:0019899	enzyme binding
0.35	GO:0004983	neuropeptide Y receptor activity
0.34	GO:0008502	melatonin receptor activity

0.50	GO:0005886	plasma membrane
0.37	GO:0098794	postsynapse
0.36	GO:0005622	intracellular
0.34	GO:0009986	cell surface
0.30	GO:0016021	integral component of membrane

tr|T1G1P9|T1G1P9_HELRO
Uncharacterized protein
Search

tr|T1G1Q0|T1G1Q0_HELRO
Uncharacterized protein
Search

0.56	GO:0006334	nucleosome assembly
0.52	GO:0006357	regulation of transcription by RNA polymerase II
0.47	GO:0002574	thrombocyte differentiation
0.47	GO:0016569	covalent chromatin modification
0.44	GO:0007283	spermatogenesis
0.41	GO:0006413	translational initiation
0.41	GO:0006351	transcription, DNA-templated
0.40	GO:0016310	phosphorylation

0.59	GO:0070577	lysine-acetylated histone binding
0.55	GO:0003682	chromatin binding
0.42	GO:0003743	translation initiation factor activity
0.41	GO:0016301	kinase activity
0.41	GO:0016787	hydrolase activity

0.65	GO:0016607	nuclear speck
0.40	GO:0005737	cytoplasm

0.41

GO:0016787

tr|T1G1Q1|T1G1Q1_HELRO
Uncharacterized protein
Search

GANAB

0.79	Neutral alpha-glucosidase AB

0.60	GO:0005975	carbohydrate metabolic process
0.36	GO:0006491	N-glycan processing
0.35	GO:0031288	sorocarp morphogenesis
0.34	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.34	GO:0043687	post-translational protein modification
0.34	GO:0006486	protein glycosylation
0.33	GO:0006886	intracellular protein transport
0.33	GO:0006457	protein folding

0.70	GO:0030246	carbohydrate binding
0.66	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.34	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity
0.33	GO:0008565	protein transporter activity
0.33	GO:0003723	RNA binding
0.33	GO:0005515	protein binding
0.32	GO:0046872	metal ion binding

0.51	GO:0017177	glucosidase II complex
0.39	GO:0042470	melanosome
0.38	GO:0005794	Golgi apparatus
0.36	GO:0031012	extracellular matrix
0.36	GO:0070062	extracellular exosome
0.34	GO:0005788	endoplasmic reticulum lumen
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.66

GO:0004553

tr|T1G1Q2|T1G1Q2_HELRO
Uncharacterized protein
Search

0.88	Iroquois-class homeodomain protein irx-1-A (Fragment)

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.45	GO:0009954	proximal/distal pattern formation
0.43	GO:0072268	pattern specification involved in metanephros development
0.42	GO:0072070	loop of Henle development
0.42	GO:0009887	animal organ morphogenesis
0.42	GO:0009790	embryo development
0.42	GO:0007379	segment specification
0.42	GO:0072210	metanephric nephron development

0.65	GO:0043565	sequence-specific DNA binding
0.39	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.36	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|T1G1Q3|T1G1Q3_HELRO
Uncharacterized protein
Search

TXNL4A

0.67	Mitosis protein dim1

0.75	GO:0000398	mRNA splicing, via spliceosome
0.42	GO:0022618	ribonucleoprotein complex assembly
0.34	GO:0051301	cell division
0.34	GO:0007049	cell cycle
0.33	GO:0009059	macromolecule biosynthetic process
0.32	GO:0044271	cellular nitrogen compound biosynthetic process
0.32	GO:0006518	peptide metabolic process
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.33	GO:0005515	protein binding
0.33	GO:0003735	structural constituent of ribosome
0.32	GO:0003723	RNA binding

0.76	GO:0005681	spliceosomal complex
0.48	GO:0031965	nuclear membrane
0.45	GO:0005682	U5 snRNP
0.44	GO:0046540	U4/U6 x U5 tri-snRNP complex
0.44	GO:0005829	cytosol
0.34	GO:0005654	nucleoplasm
0.33	GO:0015935	small ribosomal subunit
0.32	GO:0043234	protein complex

tr|T1G1Q4|T1G1Q4_HELRO
Uncharacterized protein
Search

0.10	RhoGAP domain containing protein (Fragment)

0.65	GO:0043547	positive regulation of GTPase activity
0.61	GO:0007165	signal transduction
0.38	GO:0051645	Golgi localization
0.36	GO:0051657	maintenance of organelle location
0.35	GO:0072384	organelle transport along microtubule
0.35	GO:0007030	Golgi organization

0.65	GO:0005096	GTPase activator activity
0.58	GO:0005543	phospholipid binding
0.33	GO:0003774	motor activity
0.33	GO:0046872	metal ion binding
0.32	GO:0003677	DNA binding

0.35	GO:0005622	intracellular
0.34	GO:0030054	cell junction
0.34	GO:0012505	endomembrane system
0.33	GO:0043228	non-membrane-bounded organelle
0.33	GO:0043227	membrane-bounded organelle
0.33	GO:0005886	plasma membrane

tr|T1G1Q5|T1G1Q5_HELRO
Uncharacterized protein
Search

0.46	GO:0039528	cytoplasmic pattern recognition receptor signaling pathway in response to virus
0.46	GO:0035549	positive regulation of interferon-beta secretion
0.46	GO:0043331	response to dsRNA
0.46	GO:1904469	positive regulation of tumor necrosis factor secretion
0.46	GO:1902741	positive regulation of interferon-alpha secretion
0.45	GO:2000778	positive regulation of interleukin-6 secretion
0.45	GO:0060760	positive regulation of response to cytokine stimulus
0.44	GO:0045087	innate immune response
0.44	GO:1901699	cellular response to nitrogen compound
0.43	GO:0071407	cellular response to organic cyclic compound

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.53	GO:0004386	helicase activity
0.51	GO:0003676	nucleic acid binding
0.43	GO:0004525	ribonuclease III activity
0.42	GO:0008270	zinc ion binding
0.41	GO:0005515	protein binding
0.40	GO:0043021	ribonucleoprotein complex binding

0.36	GO:0032587	ruffle membrane
0.36	GO:0005737	cytoplasm
0.35	GO:0005923	bicellular tight junction
0.35	GO:0016442	RISC complex
0.35	GO:0015629	actin cytoskeleton
0.34	GO:0005634	nucleus
0.33	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.43

EC:3.1.26.3

GO:0004525

tr|T1G1Q6|T1G1Q6_HELRO
Uncharacterized protein
Search

0.40

GO:0055085

transmembrane transport

0.30

GO:0044425

membrane part

tr|T1G1Q7|T1G1Q7_HELRO
Uncharacterized protein
Search

0.36	Collagen triple helix repeat domain containing protein

0.47	GO:0071230	cellular response to amino acid stimulus
0.47	GO:0030198	extracellular matrix organization
0.45	GO:0001654	eye development
0.44	GO:0009653	anatomical structure morphogenesis
0.44	GO:1903225	negative regulation of endodermal cell differentiation
0.43	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.42	GO:0043588	skin development
0.42	GO:0007528	neuromuscular junction development
0.41	GO:0001501	skeletal system development
0.41	GO:0061326	renal tubule development

0.65	GO:0005201	extracellular matrix structural constituent
0.47	GO:0042302	structural constituent of cuticle
0.43	GO:0048407	platelet-derived growth factor binding
0.42	GO:0046332	SMAD binding
0.40	GO:0030414	peptidase inhibitor activity
0.39	GO:0061135	endopeptidase regulator activity
0.34	GO:0005509	calcium ion binding
0.33	GO:0097493	structural molecule activity conferring elasticity
0.33	GO:0005102	receptor binding
0.33	GO:0044877	macromolecular complex binding

0.64	GO:0005581	collagen trimer
0.56	GO:0044420	extracellular matrix component
0.53	GO:0005578	proteinaceous extracellular matrix
0.44	GO:0099081	supramolecular polymer
0.44	GO:0005615	extracellular space
0.34	GO:0005788	endoplasmic reticulum lumen
0.33	GO:0005938	cell cortex
0.33	GO:0031594	neuromuscular junction
0.33	GO:1903561	extracellular vesicle
0.32	GO:0036338	viral membrane

0.32

GO:0004715

tr|T1G1Q8|T1G1Q8_HELRO
Uncharacterized protein
Search

0.12	Serine/threonine-protein kinase Nek7 (Fragment)

0.63	GO:0006468	protein phosphorylation
0.40	GO:1904355	positive regulation of telomere capping
0.40	GO:0051973	positive regulation of telomerase activity
0.40	GO:0032212	positive regulation of telomere maintenance via telomerase
0.39	GO:0051225	spindle assembly
0.38	GO:0007346	regulation of mitotic cell cycle

0.65	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0046872	metal ion binding

0.38	GO:0000922	spindle pole
0.38	GO:0005815	microtubule organizing center
0.37	GO:0005874	microtubule
0.37	GO:0005654	nucleoplasm
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.65

GO:0004674

tr|T1G1Q9|T1G1Q9_HELRO
Uncharacterized protein
Search

TRMT44

0.81	tRNA methyltransferase 44 homolog

0.63	GO:0032259	methylation
0.41	GO:0006400	tRNA modification
0.35	GO:0044260	cellular macromolecule metabolic process
0.33	GO:0006629	lipid metabolic process
0.33	GO:0035556	intracellular signal transduction
0.32	GO:0006508	proteolysis

0.63	GO:0008168	methyltransferase activity
0.49	GO:0046872	metal ion binding
0.40	GO:0140101	catalytic activity, acting on a tRNA
0.34	GO:0004435	phosphatidylinositol phospholipase C activity
0.33	GO:0004181	metallocarboxypeptidase activity
0.32	GO:0003723	RNA binding

0.33

GO:0005737

cytoplasm

0.63	EC:2.1.1	GO:0008168
0.34	KEGG:R03435	GO:0004435

tr|T1G1R0|T1G1R0_HELRO
Uncharacterized protein
Search

tr|T1G1R1|T1G1R1_HELRO
Vesicle transport protein
Search

0.68	Vesicle transport protein (Fragment)

0.69	GO:0016192	vesicle-mediated transport
0.65	GO:0015031	protein transport
0.36	GO:0016482	cytosolic transport
0.36	GO:0016197	endosomal transport

0.35	GO:0000139	Golgi membrane
0.35	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

tr|T1G1R2|T1G1R2_HELRO
Uncharacterized protein
Search

0.49	Mitogen-activated protein kinase kinase kinase 12

0.74	GO:0000186	activation of MAPKK activity
0.71	GO:0046777	protein autophosphorylation
0.70	GO:0000165	MAPK cascade
0.53	GO:0031098	stress-activated protein kinase signaling cascade
0.47	GO:2000672	negative regulation of motor neuron apoptotic process
0.45	GO:0048674	collateral sprouting of injured axon
0.45	GO:0016572	histone phosphorylation
0.44	GO:0018107	peptidyl-threonine phosphorylation
0.44	GO:2000331	regulation of terminal button organization
0.44	GO:0018105	peptidyl-serine phosphorylation

0.75	GO:0004709	MAP kinase kinase kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0019901	protein kinase binding
0.42	GO:0042803	protein homodimerization activity
0.35	GO:0005096	GTPase activator activity
0.33	GO:0046872	metal ion binding
0.33	GO:0004713	protein tyrosine kinase activity

0.48	GO:0030424	axon
0.44	GO:0030426	growth cone
0.42	GO:0005622	intracellular
0.37	GO:0005886	plasma membrane
0.34	GO:1902554	serine/threonine protein kinase complex
0.33	GO:0045202	synapse
0.33	GO:0030054	cell junction
0.30	GO:0016021	integral component of membrane

0.75

EC:2.7.11 EC:2.7.11.25

GO:0004709

tr|T1G1R3|T1G1R3_HELRO
Uncharacterized protein
Search

0.34	Proto-oncogene tyrosine-protein kinase Src

0.74	GO:0018108	peptidyl-tyrosine phosphorylation
0.61	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.44	GO:0038179	neurotrophin signaling pathway
0.42	GO:0071469	cellular response to alkaline pH
0.41	GO:0090594	inflammatory response to wounding
0.41	GO:0023014	signal transduction by protein phosphorylation
0.40	GO:0002446	neutrophil mediated immunity
0.40	GO:0035556	intracellular signal transduction
0.38	GO:0042742	defense response to bacterium
0.38	GO:0016477	cell migration

0.74	GO:0004713	protein tyrosine kinase activity
0.62	GO:0019199	transmembrane receptor protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0005030	neurotrophin receptor activity
0.44	GO:0005057	signal transducer activity, downstream of receptor
0.37	GO:0004674	protein serine/threonine kinase activity
0.35	GO:0005102	receptor binding
0.35	GO:0038064	collagen receptor activity

0.44	GO:0005887	integral component of plasma membrane
0.36	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.33	GO:0005737	cytoplasm

0.74

GO:0004713

tr|T1G1R4|T1G1R4_HELRO
Translocon-associated protein subunit beta
Search

0.83	Translocon-associated protein subunit beta

0.42

GO:0006613

cotranslational protein targeting to membrane

0.37

GO:0005048

signal sequence binding

0.70	GO:0005783	endoplasmic reticulum
0.68	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.64	GO:0031984	organelle subcompartment
0.37	GO:0005786	signal recognition particle, endoplasmic reticulum targeting
0.30	GO:0031224	intrinsic component of membrane

tr|T1G1R5|T1G1R5_HELRO
Uncharacterized protein
Search

0.87	Neuralized E3 ubiquitin protein ligase 2

0.61	GO:0035556	intracellular signal transduction
0.41	GO:0032446	protein modification by small protein conjugation
0.36	GO:0034227	tRNA thio-modification
0.36	GO:0002098	tRNA wobble uridine modification

0.35	GO:0000049	tRNA binding
0.34	GO:0016779	nucleotidyltransferase activity
0.34	GO:0008270	zinc ion binding

0.44	GO:0005622	intracellular
0.33	GO:0043227	membrane-bounded organelle

0.34

EC:2.7.7

GO:0016779

tr|T1G1R6|T1G1R6_HELRO
Uncharacterized protein
Search

0.55	RING finger protein 157

0.39	GO:0016567	protein ubiquitination
0.38	GO:0006887	exocytosis
0.35	GO:1903506	regulation of nucleic acid-templated transcription
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression

0.58	GO:0016874	ligase activity
0.39	GO:0004842	ubiquitin-protein transferase activity
0.39	GO:0046872	metal ion binding
0.36	GO:0043565	sequence-specific DNA binding
0.35	GO:0003700	DNA binding transcription factor activity

0.38	GO:0000145	exocyst
0.35	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.58	EC:6	GO:0016874
0.39	KEGG:R03876	GO:0004842

tr|T1G1R7|T1G1R7_HELRO
Proteasome assembly chaperone 2
Search

0.42	Proteasome assembly chaperone 2

0.49

GO:0043248

proteasome assembly

0.73	GO:1905369	endopeptidase complex
0.59	GO:0043234	protein complex
0.45	GO:0044424	intracellular part
0.40	GO:0043227	membrane-bounded organelle

tr|T1G1R8|T1G1R8_HELRO
Uncharacterized protein
Search

0.62	Zinc finger C2HC-type containing 1B

0.40	GO:0046872	metal ion binding
0.35	GO:0003676	nucleic acid binding

0.30

GO:0044425

membrane part

tr|T1G1R9|T1G1R9_HELRO
Uncharacterized protein
Search

0.44	Glucose-dependent insulinotropic receptor (Fragment)

0.35	GO:0070647	protein modification by small protein conjugation or removal
0.35	GO:0009190	cyclic nucleotide biosynthetic process
0.35	GO:0070143	mitochondrial alanyl-tRNA aminoacylation
0.34	GO:0007165	signal transduction
0.34	GO:0006508	proteolysis
0.33	GO:1990823	response to leukemia inhibitory factor
0.33	GO:0043966	histone H3 acetylation
0.33	GO:0060078	regulation of postsynaptic membrane potential
0.33	GO:0071103	DNA conformation change
0.33	GO:2001141	regulation of RNA biosynthetic process

0.35	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.35	GO:0017056	structural constituent of nuclear pore
0.35	GO:0016849	phosphorus-oxygen lyase activity
0.34	GO:0008080	N-acetyltransferase activity
0.34	GO:0046872	metal ion binding
0.34	GO:0004842	ubiquitin-protein transferase activity
0.34	GO:0004983	neuropeptide Y receptor activity
0.34	GO:0004813	alanine-tRNA ligase activity
0.33	GO:0003676	nucleic acid binding
0.33	GO:0052590	sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity

0.35	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0044444	cytoplasmic part
0.34	GO:0012505	endomembrane system
0.34	GO:0032991	macromolecular complex
0.34	GO:0044446	intracellular organelle part
0.33	GO:0045211	postsynaptic membrane
0.33	GO:0031975	envelope
0.33	GO:0030054	cell junction
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.32	GO:0070013	intracellular organelle lumen

0.35	EC:4.6	GO:0016849
0.34	KEGG:R03876	GO:0004842

tr|T1G1S0|T1G1S0_HELRO
Uncharacterized protein
Search

0.44	GO:0030198	extracellular matrix organization
0.43	GO:0007275	multicellular organism development
0.43	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.42	GO:0071230	cellular response to amino acid stimulus
0.41	GO:0033622	integrin activation
0.41	GO:0007155	cell adhesion
0.41	GO:0051894	positive regulation of focal adhesion assembly
0.40	GO:0009653	anatomical structure morphogenesis
0.40	GO:0009888	tissue development
0.40	GO:0010951	negative regulation of endopeptidase activity

0.70	GO:0005201	extracellular matrix structural constituent
0.41	GO:0005178	integrin binding
0.41	GO:0042302	structural constituent of cuticle
0.40	GO:0004867	serine-type endopeptidase inhibitor activity
0.38	GO:0008061	chitin binding
0.38	GO:0048407	platelet-derived growth factor binding
0.35	GO:0046332	SMAD binding
0.35	GO:0002020	protease binding
0.35	GO:0008201	heparin binding
0.34	GO:0042802	identical protein binding

0.68	GO:0005581	collagen trimer
0.61	GO:0044420	extracellular matrix component
0.57	GO:0005578	proteinaceous extracellular matrix
0.44	GO:0099081	supramolecular polymer
0.38	GO:0005615	extracellular space
0.38	GO:0031594	neuromuscular junction
0.35	GO:0005788	endoplasmic reticulum lumen
0.34	GO:0005911	cell-cell junction
0.33	GO:0005938	cell cortex
0.33	GO:0005829	cytosol

0.32

GO:0004674

tr|T1G1S1|T1G1S1_HELRO
Uncharacterized protein
Search

SLC35A2

0.67	UDP-N-acetylglucosamine transporter

0.69	GO:0008643	carbohydrate transport
0.63	GO:1902600	hydrogen ion transmembrane transport

0.79	GO:0005351	sugar:proton symporter activity
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.74	GO:0000139	Golgi membrane
0.34	GO:0005783	endoplasmic reticulum
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

tr|T1G1S2|T1G1S2_HELRO
Uncharacterized protein
Search

0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:1903506	regulation of nucleic acid-templated transcription
0.35	GO:0010468	regulation of gene expression

0.51

GO:0003676

nucleic acid binding

0.36

GO:0005634

nucleus

tr|T1G1S4|T1G1S4_HELRO
Uncharacterized protein
Search

RNF181

0.37	E3 ubiquitin-protein ligase

0.50	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.50	GO:0000209	protein polyubiquitination
0.49	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.38	GO:0016192	vesicle-mediated transport
0.37	GO:0009788	negative regulation of abscisic acid-activated signaling pathway
0.36	GO:0009737	response to abscisic acid
0.33	GO:0006355	regulation of transcription, DNA-templated

0.50	GO:0016874	ligase activity
0.48	GO:0061630	ubiquitin protein ligase activity
0.43	GO:0008270	zinc ion binding
0.37	GO:0003860	3-hydroxyisobutyryl-CoA hydrolase activity
0.34	GO:0003700	DNA binding transcription factor activity
0.33	GO:0003676	nucleic acid binding

0.35	GO:0005829	cytosol
0.34	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.50

GO:0016874

tr|T1G1S5|T1G1S5_HELRO
Sulfhydryl oxidase
Search

0.60	Sulfhydryl oxidase

0.52	GO:0055114	oxidation-reduction process
0.42	GO:0042246	tissue regeneration
0.42	GO:0001889	liver development
0.41	GO:0045041	protein import into mitochondrial intermembrane space
0.38	GO:0006879	cellular iron ion homeostasis
0.38	GO:0007507	heart development
0.38	GO:0034599	cellular response to oxidative stress
0.36	GO:0016310	phosphorylation
0.34	GO:0006270	DNA replication initiation
0.34	GO:0036388	pre-replicative complex assembly

0.84	GO:0016972	thiol oxidase activity
0.42	GO:0015035	protein disulfide oxidoreductase activity
0.40	GO:0050660	flavin adenine dinucleotide binding
0.38	GO:0019205	nucleobase-containing compound kinase activity
0.37	GO:0042803	protein homodimerization activity
0.36	GO:0005524	ATP binding
0.34	GO:0017116	single-stranded DNA-dependent ATP-dependent DNA helicase activity
0.34	GO:0008083	growth factor activity
0.34	GO:0008379	thioredoxin peroxidase activity
0.33	GO:0003688	DNA replication origin binding

0.42	GO:0005739	mitochondrion
0.40	GO:0031970	organelle envelope lumen
0.39	GO:0005829	cytosol
0.35	GO:0042555	MCM complex
0.34	GO:0030529	intracellular ribonucleoprotein complex
0.34	GO:0005656	nuclear pre-replicative complex
0.34	GO:0071162	CMG complex
0.34	GO:0031298	replication fork protection complex
0.34	GO:0000781	chromosome, telomeric region
0.33	GO:0031090	organelle membrane

0.84

EC:1.8.3.2

GO:0016972

tr|T1G1S6|T1G1S6_HELRO
Uncharacterized protein
Search

0.43	Cuticle collagen dpy-5

0.39	GO:0048598	embryonic morphogenesis
0.39	GO:0010951	negative regulation of endopeptidase activity
0.39	GO:0048646	anatomical structure formation involved in morphogenesis
0.38	GO:0030903	notochord development
0.37	GO:0007492	endoderm development
0.37	GO:0060322	head development
0.37	GO:0009887	animal organ morphogenesis
0.36	GO:0007399	nervous system development
0.36	GO:0006508	proteolysis
0.36	GO:0030154	cell differentiation

0.62	GO:0042302	structural constituent of cuticle
0.44	GO:0005201	extracellular matrix structural constituent
0.39	GO:0004867	serine-type endopeptidase inhibitor activity
0.38	GO:0004252	serine-type endopeptidase activity
0.36	GO:0042802	identical protein binding
0.36	GO:0008289	lipid binding
0.34	GO:0045735	nutrient reservoir activity
0.33	GO:0009982	pseudouridine synthase activity
0.33	GO:0030246	carbohydrate binding
0.33	GO:0008186	RNA-dependent ATPase activity

0.62	GO:0005581	collagen trimer
0.43	GO:0005604	basement membrane
0.34	GO:0019867	outer membrane
0.33	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.38

GO:0004252

tr|T1G1S7|T1G1S7_HELRO
Uncharacterized protein
Search

PGRMC1

0.92	Membrane-associated progesterone receptor component

0.46	GO:1903538	regulation of meiotic cell cycle process involved in oocyte maturation
0.38	GO:1903537	meiotic cell cycle process involved in oocyte maturation
0.35	GO:0099563	modification of synaptic structure
0.35	GO:0043312	neutrophil degranulation
0.35	GO:1905809	negative regulation of synapse organization
0.34	GO:1903078	positive regulation of protein localization to plasma membrane
0.34	GO:0008306	associative learning
0.34	GO:0007613	memory
0.34	GO:0007411	axon guidance
0.32	GO:0055114	oxidation-reduction process

0.42	GO:0005496	steroid binding
0.41	GO:0020037	heme binding
0.34	GO:0005515	protein binding
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.34	GO:0042562	hormone binding
0.34	GO:0043178	alcohol binding

0.43	GO:0012505	endomembrane system
0.38	GO:0070062	extracellular exosome
0.38	GO:0031984	organelle subcompartment
0.37	GO:0098588	bounding membrane of organelle
0.37	GO:0042585	germinal vesicle
0.37	GO:1990385	meiotic spindle midzone
0.37	GO:0106003	amyloid-beta complex
0.36	GO:0030496	midbody
0.36	GO:0043025	neuronal cell body
0.35	GO:0044428	nuclear part

0.34

GO:0032440

tr|T1G1S8|T1G1S8_HELRO
Uncharacterized protein
Search

HDAC11

0.50	Histone deacetylase

0.68	GO:0016575	histone deacetylation
0.48	GO:0006351	transcription, DNA-templated
0.47	GO:1903506	regulation of nucleic acid-templated transcription
0.47	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.47	GO:0010468	regulation of gene expression

0.69	GO:0004407	histone deacetylase activity
0.62	GO:0034979	NAD-dependent protein deacetylase activity

0.54	GO:0005634	nucleus
0.47	GO:0031974	membrane-enclosed lumen
0.45	GO:1902494	catalytic complex
0.43	GO:0044446	intracellular organelle part
0.42	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.69

EC:3.5.1.98

GO:0004407

tr|T1G1S9|T1G1S9_HELRO
Uncharacterized protein
Search

0.92	Gastrulation brain homeobox protein

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0051960	regulation of nervous system development
0.53	GO:0007417	central nervous system development
0.51	GO:0021903	rostrocaudal neural tube patterning
0.51	GO:0048513	animal organ development
0.51	GO:0007411	axon guidance
0.51	GO:0060322	head development
0.50	GO:0001569	branching involved in blood vessel morphogenesis

0.64	GO:0043565	sequence-specific DNA binding
0.49	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.48	GO:0001047	core promoter binding
0.47	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.46	GO:0001012	RNA polymerase II regulatory region DNA binding
0.45	GO:0003690	double-stranded DNA binding
0.34	GO:0004000	adenosine deaminase activity

0.61	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.34

EC:3.5.4.4

GO:0004000

tr|T1G1T0|T1G1T0_HELRO
Uncharacterized protein
Search

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.42	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle
0.42	GO:0000082	G1/S transition of mitotic cell cycle
0.38	GO:0007631	feeding behavior
0.38	GO:0018108	peptidyl-tyrosine phosphorylation
0.37	GO:0097211	cellular response to gonadotropin-releasing hormone
0.37	GO:0010447	response to acidic pH

0.72	GO:0004930	G-protein coupled receptor activity
0.68	GO:0001653	peptide receptor activity
0.41	GO:0016500	protein-hormone receptor activity
0.38	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.37	GO:0050254	rhodopsin kinase activity
0.36	GO:0042277	peptide binding

0.35

GO:0005887

integral component of plasma membrane

0.38

GO:0004715

tr|T1G1T1|T1G1T1_HELRO
Uncharacterized protein
Search

0.72	Neuropeptides capa receptor

0.75	GO:0007218	neuropeptide signaling pathway
0.34	GO:0006468	protein phosphorylation

0.75	GO:0008188	neuropeptide receptor activity
0.37	GO:0016520	growth hormone-releasing hormone receptor activity
0.36	GO:0050254	rhodopsin kinase activity
0.35	GO:0004997	thyrotropin-releasing hormone receptor activity

0.46

GO:0005887

integral component of plasma membrane

0.36

EC:2.7.11.14

GO:0050254

tr|T1G1T2|T1G1T2_HELRO
Uncharacterized protein
Search

0.77

GO:0006030

chitin metabolic process

0.76

GO:0008061

chitin binding

0.66

GO:0005576

extracellular region

tr|T1G1T3|T1G1T3_HELRO
Uncharacterized protein
Search

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.46	GO:0072137	condensed mesenchymal cell proliferation
0.45	GO:0072307	regulation of metanephric nephron tubule epithelial cell differentiation
0.45	GO:0043931	ossification involved in bone maturation
0.45	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.44	GO:0035329	hippo signaling
0.44	GO:0001658	branching involved in ureteric bud morphogenesis
0.44	GO:0060122	inner ear receptor cell stereocilium organization
0.43	GO:0007507	heart development
0.43	GO:0021987	cerebral cortex development

0.70	GO:0005509	calcium ion binding
0.37	GO:0004930	G-protein coupled receptor activity
0.36	GO:0042803	protein homodimerization activity
0.34	GO:0045296	cadherin binding
0.33	GO:0004867	serine-type endopeptidase inhibitor activity
0.33	GO:0004725	protein tyrosine phosphatase activity
0.33	GO:0030246	carbohydrate binding
0.32	GO:0008233	peptidase activity

0.56	GO:0005886	plasma membrane
0.44	GO:0045177	apical part of cell
0.37	GO:0098858	actin-based cell projection
0.35	GO:0070062	extracellular exosome
0.34	GO:0005911	cell-cell junction
0.34	GO:0005622	intracellular
0.33	GO:0032421	stereocilium bundle
0.33	GO:0005912	adherens junction
0.33	GO:0043005	neuron projection
0.32	GO:0044422	organelle part

0.33

GO:0004725

tr|T1G1T4|T1G1T4_HELRO
Uncharacterized protein
Search

0.10	Collagen type I alpha 2 (Fragment)

0.44	GO:0030199	collagen fibril organization
0.44	GO:0071230	cellular response to amino acid stimulus
0.44	GO:0043589	skin morphogenesis
0.44	GO:0070208	protein heterotrimerization
0.43	GO:0007179	transforming growth factor beta receptor signaling pathway
0.43	GO:0072359	circulatory system development
0.43	GO:0007266	Rho protein signal transduction
0.42	GO:0001501	skeletal system development
0.42	GO:0008217	regulation of blood pressure
0.38	GO:0009405	pathogenesis

0.64	GO:0005201	extracellular matrix structural constituent
0.45	GO:0048407	platelet-derived growth factor binding
0.43	GO:0042302	structural constituent of cuticle
0.43	GO:0002020	protease binding
0.43	GO:0046332	SMAD binding
0.42	GO:0030674	protein binding, bridging
0.41	GO:0042802	identical protein binding
0.38	GO:0005178	integrin binding
0.36	GO:0008061	chitin binding
0.35	GO:0042289	MHC class II protein binding

0.58	GO:0005581	collagen trimer
0.49	GO:0044420	extracellular matrix component
0.47	GO:0005578	proteinaceous extracellular matrix
0.41	GO:0099081	supramolecular polymer
0.41	GO:0005615	extracellular space
0.40	GO:0005783	endoplasmic reticulum
0.37	GO:0019867	outer membrane
0.35	GO:1990316	Atg1/ULK1 kinase complex
0.33	GO:0046695	SLIK (SAGA-like) complex
0.33	GO:0000124	SAGA complex

0.34

GO:0004252

tr|T1G1T5|T1G1T5_HELRO
Uncharacterized protein
Search

0.45	GO:0071230	cellular response to amino acid stimulus
0.45	GO:0030198	extracellular matrix organization
0.43	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.40	GO:0009888	tissue development
0.40	GO:0009653	anatomical structure morphogenesis
0.40	GO:0048513	animal organ development
0.40	GO:0007155	cell adhesion
0.39	GO:0033622	integrin activation
0.39	GO:0001568	blood vessel development
0.39	GO:0051894	positive regulation of focal adhesion assembly

0.68	GO:0005201	extracellular matrix structural constituent
0.43	GO:0042302	structural constituent of cuticle
0.41	GO:0048407	platelet-derived growth factor binding
0.39	GO:0005178	integrin binding
0.36	GO:0004867	serine-type endopeptidase inhibitor activity
0.35	GO:0043394	proteoglycan binding
0.35	GO:0046332	SMAD binding
0.35	GO:0002020	protease binding
0.35	GO:0008201	heparin binding
0.34	GO:0008061	chitin binding

0.66	GO:0005581	collagen trimer
0.62	GO:0044420	extracellular matrix component
0.58	GO:0005578	proteinaceous extracellular matrix
0.42	GO:0099081	supramolecular polymer
0.38	GO:0005615	extracellular space
0.34	GO:1903561	extracellular vesicle
0.34	GO:0046695	SLIK (SAGA-like) complex
0.34	GO:0000124	SAGA complex
0.33	GO:0005669	transcription factor TFIID complex
0.33	GO:0019867	outer membrane

0.32

GO:0004553

tr|T1G1T6|T1G1T6_HELRO
Uncharacterized protein
Search

CDK20

0.80	CMGC/CDK protein kinase

0.62	GO:0006468	protein phosphorylation
0.47	GO:1904031	positive regulation of cyclin-dependent protein kinase activity
0.44	GO:0060271	cilium assembly
0.41	GO:0051301	cell division
0.39	GO:0007275	multicellular organism development
0.38	GO:0007049	cell cycle

0.69	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0019912	cyclin-dependent protein kinase activating kinase activity
0.48	GO:0004693	cyclin-dependent protein serine/threonine kinase activity
0.34	GO:0005515	protein binding

0.69	GO:0070985	TFIIK complex
0.40	GO:0005929	cilium
0.36	GO:0005737	cytoplasm

0.69

EC:2.7.11.23

GO:0008353

tr|T1G1T7|T1G1T7_HELRO
Uncharacterized protein
Search

tr|T1G1T8|T1G1T8_HELRO
Protein YIPF
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tr|T1G1T9|T1G1T9_HELRO
Uncharacterized protein
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0.41	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.40	GO:0030198	extracellular matrix organization
0.39	GO:0052548	regulation of endopeptidase activity
0.39	GO:0007275	multicellular organism development
0.38	GO:0016525	negative regulation of angiogenesis
0.38	GO:0032268	regulation of cellular protein metabolic process
0.38	GO:0051346	negative regulation of hydrolase activity
0.38	GO:0009653	anatomical structure morphogenesis
0.38	GO:0009888	tissue development
0.37	GO:0071310	cellular response to organic substance

0.69	GO:0005201	extracellular matrix structural constituent
0.45	GO:0042302	structural constituent of cuticle
0.38	GO:0004867	serine-type endopeptidase inhibitor activity
0.37	GO:0048407	platelet-derived growth factor binding
0.36	GO:0005178	integrin binding
0.35	GO:0030169	low-density lipoprotein particle binding
0.35	GO:0038187	pattern recognition receptor activity
0.34	GO:0042802	identical protein binding
0.33	GO:0030246	carbohydrate binding
0.33	GO:0038023	signaling receptor activity

0.68	GO:0005581	collagen trimer
0.63	GO:0005604	basement membrane
0.41	GO:0098645	collagen network
0.36	GO:0005615	extracellular space
0.35	GO:0005783	endoplasmic reticulum
0.32	GO:0019867	outer membrane
0.30	GO:0016021	integral component of membrane

0.32

GO:0016787

tr|T1G1U0|T1G1U0_HELRO
Uncharacterized protein
Search

0.58	GO:0016874	ligase activity
0.35	GO:0046872	metal ion binding

0.50

GO:0005856

cytoskeleton

0.58

GO:0016874

tr|T1G1U1|T1G1U1_HELRO
Uncharacterized protein
Search

0.35	Collagen alpha 1(XIV) chain

0.41	GO:0030199	collagen fibril organization
0.40	GO:0043589	skin morphogenesis
0.40	GO:0070208	protein heterotrimerization
0.39	GO:0001501	skeletal system development
0.39	GO:0007266	Rho protein signal transduction
0.39	GO:0071230	cellular response to amino acid stimulus
0.39	GO:0007179	transforming growth factor beta receptor signaling pathway
0.39	GO:0008217	regulation of blood pressure
0.39	GO:0072359	circulatory system development
0.36	GO:0006030	chitin metabolic process

0.63	GO:0005201	extracellular matrix structural constituent
0.47	GO:0042302	structural constituent of cuticle
0.40	GO:0048407	platelet-derived growth factor binding
0.39	GO:0046332	SMAD binding
0.39	GO:0002020	protease binding
0.39	GO:0030674	protein binding, bridging
0.39	GO:0005509	calcium ion binding
0.37	GO:0042802	identical protein binding
0.36	GO:0008061	chitin binding
0.35	GO:0005044	scavenger receptor activity

0.59	GO:0005581	collagen trimer
0.50	GO:0031012	extracellular matrix
0.43	GO:0005615	extracellular space
0.38	GO:0099081	supramolecular polymer
0.37	GO:0005783	endoplasmic reticulum
0.34	GO:1903561	extracellular vesicle
0.34	GO:0031594	neuromuscular junction
0.33	GO:0019867	outer membrane
0.32	GO:0070013	intracellular organelle lumen
0.32	GO:0044446	intracellular organelle part

0.33

GO:0004553

tr|T1G1U2|T1G1U2_HELRO
Uncharacterized protein
Search

0.61	GO:0007015	actin filament organization
0.48	GO:0007155	cell adhesion
0.40	GO:0006897	endocytosis
0.37	GO:0035023	regulation of Rho protein signal transduction
0.36	GO:0000281	mitotic cytokinesis
0.36	GO:0018108	peptidyl-tyrosine phosphorylation
0.36	GO:0065009	regulation of molecular function
0.35	GO:0035556	intracellular signal transduction
0.35	GO:0006886	intracellular protein transport

0.58	GO:0004104	cholinesterase activity
0.37	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.36	GO:0004713	protein tyrosine kinase activity
0.36	GO:0016874	ligase activity
0.36	GO:0035091	phosphatidylinositol binding
0.34	GO:1901265	nucleoside phosphate binding
0.34	GO:0036094	small molecule binding
0.33	GO:0097367	carbohydrate derivative binding
0.33	GO:0008144	drug binding

0.36	GO:0030659	cytoplasmic vesicle membrane
0.30	GO:0016021	integral component of membrane

0.58

EC:3.1.1.8

GO:0004104

tr|T1G1U3|T1G1U3_HELRO
Uncharacterized protein
Search

0.39	Tetratricopeptide repeat protein 17

0.40	GO:0030041	actin filament polymerization
0.36	GO:0006004	fucose metabolic process
0.36	GO:0019673	GDP-mannose metabolic process

0.36	GO:0008446	GDP-mannose 4,6-dehydratase activity
0.34	GO:0016757	transferase activity, transferring glycosyl groups

0.38	GO:0015629	actin cytoskeleton
0.30	GO:0031224	intrinsic component of membrane

0.36	EC:4.2.1.47	GO:0008446
0.36	KEGG:R00888	GO:0008446

tr|T1G1U4|T1G1U4_HELRO
Uncharacterized protein
Search

MMD

0.90	Monocyte to macrophage differentiation-associated

0.70	GO:0019835	cytolysis
0.47	GO:0045666	positive regulation of neuron differentiation
0.46	GO:0045860	positive regulation of protein kinase activity
0.44	GO:0032880	regulation of protein localization
0.42	GO:0003007	heart morphogenesis
0.41	GO:0006468	protein phosphorylation
0.41	GO:0036302	atrioventricular canal development
0.40	GO:0003197	endocardial cushion development
0.40	GO:0072132	mesenchyme morphogenesis
0.38	GO:0046578	regulation of Ras protein signal transduction

0.41	GO:0004672	protein kinase activity
0.33	GO:0004872	receptor activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.43	GO:0005794	Golgi apparatus
0.37	GO:0031902	late endosome membrane
0.36	GO:0005765	lysosomal membrane
0.33	GO:0005887	integral component of plasma membrane

tr|T1G1U5|T1G1U5_HELRO
Uncharacterized protein
Search

0.42	Sodium-dependent dopamine transporter

0.76	GO:0006836	neurotransmitter transport
0.55	GO:0055085	transmembrane transport
0.50	GO:0015872	dopamine transport
0.46	GO:0099509	regulation of presynaptic cytosolic calcium ion concentration
0.46	GO:1990834	response to odorant
0.45	GO:0042745	circadian sleep/wake cycle
0.44	GO:0030431	sleep
0.44	GO:0090493	catecholamine uptake
0.43	GO:0008344	adult locomotory behavior
0.43	GO:0001963	synaptic transmission, dopaminergic

0.79	GO:0005328	neurotransmitter:sodium symporter activity
0.50	GO:0005329	dopamine transmembrane transporter activity
0.47	GO:0019811	cocaine binding
0.38	GO:0005254	chloride channel activity
0.38	GO:0005275	amine transmembrane transporter activity
0.33	GO:0046872	metal ion binding
0.32	GO:0016772	transferase activity, transferring phosphorus-containing groups

0.46	GO:0098793	presynapse
0.41	GO:0005887	integral component of plasma membrane
0.40	GO:0043005	neuron projection
0.40	GO:0032809	neuronal cell body membrane
0.39	GO:0031256	leading edge membrane
0.39	GO:0031253	cell projection membrane
0.39	GO:0097060	synaptic membrane

0.32

EC:2.7

GO:0016772

tr|T1G1U6|T1G1U6_HELRO
Uncharacterized protein
Search

tr|T1G1U7|T1G1U7_HELRO
Uncharacterized protein
Search

0.48	Fibrinogen alpha chain

0.80	GO:0030168	platelet activation
0.73	GO:0051258	protein polymerization
0.68	GO:0072378	blood coagulation, fibrin clot formation
0.67	GO:0034116	positive regulation of heterotypic cell-cell adhesion
0.67	GO:0042730	fibrinolysis
0.66	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.66	GO:0045907	positive regulation of vasoconstriction
0.66	GO:2000352	negative regulation of endothelial cell apoptotic process
0.65	GO:0031639	plasminogen activation
0.65	GO:0034109	homotypic cell-cell adhesion

0.76	GO:0030674	protein binding, bridging
0.69	GO:0005102	receptor binding
0.61	GO:0050839	cell adhesion molecule binding
0.49	GO:0005198	structural molecule activity
0.38	GO:0046872	metal ion binding
0.37	GO:0042803	protein homodimerization activity
0.37	GO:1990782	protein tyrosine kinase binding
0.35	GO:0030246	carbohydrate binding
0.35	GO:0004222	metalloendopeptidase activity

0.83	GO:0005577	fibrinogen complex
0.66	GO:0031091	platelet alpha granule
0.62	GO:0009897	external side of plasma membrane
0.51	GO:0005938	cell cortex
0.41	GO:0072562	blood microparticle
0.39	GO:0070062	extracellular exosome
0.38	GO:0034774	secretory granule lumen
0.37	GO:0005578	proteinaceous extracellular matrix
0.37	GO:0005788	endoplasmic reticulum lumen
0.36	GO:0005581	collagen trimer

0.35

GO:0004222

tr|T1G1U8|T1G1U8_HELRO
Uncharacterized protein
Search

0.10	GRAM domain containing 1B

0.34	GO:0007076	mitotic chromosome condensation
0.33	GO:0006364	rRNA processing

0.32

GO:0016740

transferase activity

0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016740

tr|T1G1U9|T1G1U9_HELRO
Uncharacterized protein
Search

0.37	Dual specificity mitogen-activated protein kinase kinase MAPKK

0.63	GO:0006468	protein phosphorylation
0.47	GO:0032147	activation of protein kinase activity
0.44	GO:0031098	stress-activated protein kinase signaling cascade
0.43	GO:0043406	positive regulation of MAP kinase activity
0.43	GO:0051726	regulation of cell cycle
0.41	GO:0000750	pheromone-dependent signal transduction involved in conjugation with cellular fusion
0.41	GO:2000241	regulation of reproductive process
0.41	GO:0060284	regulation of cell development
0.41	GO:0010941	regulation of cell death
0.41	GO:0046999	regulation of conjugation

0.65	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0004708	MAP kinase kinase activity
0.40	GO:0031435	mitogen-activated protein kinase kinase kinase binding
0.34	GO:0008897	holo-[acyl-carrier-protein] synthase activity
0.33	GO:0000287	magnesium ion binding
0.33	GO:0004713	protein tyrosine kinase activity

0.41	GO:0051286	cell tip
0.39	GO:0032153	cell division site
0.35	GO:0005622	intracellular
0.33	GO:0043025	neuronal cell body
0.33	GO:0030424	axon
0.30	GO:0016020	membrane

0.65

GO:0004674

tr|T1G1V0|T1G1V0_HELRO
Uncharacterized protein
Search

0.11

Fukutin

0.61	GO:0046329	negative regulation of JNK cascade
0.60	GO:0035269	protein O-linked mannosylation
0.56	GO:0008285	negative regulation of cell proliferation
0.50	GO:0060049	regulation of protein glycosylation
0.47	GO:0001570	vasculogenesis
0.47	GO:0048747	muscle fiber development
0.39	GO:0043486	histone exchange
0.36	GO:0007399	nervous system development
0.35	GO:0007517	muscle organ development
0.35	GO:0016477	cell migration

0.35	GO:0016740	transferase activity
0.34	GO:0008324	cation transmembrane transporter activity
0.34	GO:0005216	ion channel activity
0.33	GO:0015318	inorganic molecular entity transmembrane transporter activity

0.58	GO:0005801	cis-Golgi network
0.53	GO:0005794	Golgi apparatus
0.52	GO:0005783	endoplasmic reticulum
0.48	GO:0005634	nucleus
0.37	GO:0098588	bounding membrane of organelle
0.37	GO:0031984	organelle subcompartment
0.35	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
0.35	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane

0.35

GO:0016740

tr|T1G1V1|T1G1V1_HELRO
Uncharacterized protein
Search

tr|T1G1V2|T1G1V2_HELRO
Uncharacterized protein
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tr|T1G1V3|T1G1V3_HELRO
Uncharacterized protein
Search

0.15	Huntingtin-interacting protein 1 (Fragment)

0.82	GO:0048268	clathrin coat assembly
0.77	GO:0006915	apoptotic process
0.72	GO:0072583	clathrin-dependent endocytosis
0.43	GO:2000588	positive regulation of platelet-derived growth factor receptor-beta signaling pathway
0.42	GO:0099632	protein transport within plasma membrane
0.42	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway
0.42	GO:0048260	positive regulation of receptor-mediated endocytosis
0.41	GO:0051897	positive regulation of protein kinase B signaling
0.41	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.40	GO:0050821	protein stabilization

0.81	GO:0030276	clathrin binding
0.76	GO:0035091	phosphatidylinositol binding
0.74	GO:0003779	actin binding
0.43	GO:0035612	AP-2 adaptor complex binding
0.42	GO:0035254	glutamate receptor binding
0.42	GO:0005154	epidermal growth factor receptor binding
0.42	GO:0098748	endocytic adaptor activity
0.41	GO:0008009	chemokine activity
0.40	GO:0005200	structural constituent of cytoskeleton
0.39	GO:0042803	protein homodimerization activity

0.79	GO:0030136	clathrin-coated vesicle
0.44	GO:0098890	extrinsic component of postsynaptic membrane
0.44	GO:0098888	extrinsic component of presynaptic membrane
0.41	GO:0030666	endocytic vesicle membrane
0.41	GO:0030132	clathrin coat of coated pit
0.40	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.40	GO:0030131	clathrin adaptor complex
0.40	GO:0030120	vesicle coat
0.39	GO:0005794	Golgi apparatus
0.38	GO:0005856	cytoskeleton

tr|T1G1V4|T1G1V4_HELRO
Uncharacterized protein
Search

0.46	Forkhead box protein K2 (Fragment)

0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.50	GO:0051254	positive regulation of RNA metabolic process
0.49	GO:0010557	positive regulation of macromolecule biosynthetic process
0.49	GO:0031328	positive regulation of cellular biosynthetic process
0.46	GO:0051253	negative regulation of RNA metabolic process
0.46	GO:0010558	negative regulation of macromolecule biosynthetic process
0.46	GO:0031327	negative regulation of cellular biosynthetic process
0.44	GO:0030154	cell differentiation

0.64	GO:0043565	sequence-specific DNA binding
0.60	GO:0003700	DNA binding transcription factor activity
0.52	GO:0001012	RNA polymerase II regulatory region DNA binding
0.49	GO:0003690	double-stranded DNA binding
0.39	GO:0000287	magnesium ion binding
0.35	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|T1G1V5|T1G1V5_HELRO
Uncharacterized protein
Search

0.70	NACHT and WD repeat domain-containing protein 2

0.57

GO:0006886

intracellular protein transport

0.40	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

tr|T1G1V7|T1G1V7_HELRO
Uncharacterized protein
Search

0.76	Serine/threonine-protein kinase Doa

0.63	GO:0006468	protein phosphorylation
0.48	GO:0006486	protein glycosylation
0.37	GO:0032526	response to retinoic acid
0.37	GO:0045721	negative regulation of gluconeogenesis
0.37	GO:0010212	response to ionizing radiation
0.37	GO:0043484	regulation of RNA splicing
0.36	GO:0018212	peptidyl-tyrosine modification
0.34	GO:0015031	protein transport

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0016757	transferase activity, transferring glycosyl groups
0.36	GO:0042802	identical protein binding
0.34	GO:0031625	ubiquitin protein ligase binding
0.33	GO:0003676	nucleic acid binding

0.34	GO:0005634	nucleus
0.34	GO:0070062	extracellular exosome
0.33	GO:0000139	Golgi membrane
0.33	GO:0043233	organelle lumen
0.30	GO:0031224	intrinsic component of membrane

0.44

GO:0016757

tr|T1G1V8|T1G1V8_HELRO
Uncharacterized protein
Search

IFT172

0.96	LOW QUALITY PROTEIN: intraflagellar transport protein 172 homolog

0.58	GO:0060271	cilium assembly
0.57	GO:0070986	left/right axis specification
0.57	GO:0061525	hindgut development
0.56	GO:0045880	positive regulation of smoothened signaling pathway
0.56	GO:0021522	spinal cord motor neuron differentiation
0.55	GO:0001947	heart looping
0.55	GO:0060021	palate development
0.55	GO:0001843	neural tube closure
0.55	GO:0050680	negative regulation of epithelial cell proliferation
0.55	GO:0031122	cytoplasmic microtubule organization

0.35	GO:0005515	protein binding
0.35	GO:0004867	serine-type endopeptidase inhibitor activity

0.75	GO:0031514	motile cilium
0.59	GO:0097598	sperm cytoplasmic droplet
0.57	GO:0030992	intraciliary transport particle B
0.54	GO:0044441	ciliary part
0.49	GO:0032838	plasma membrane bounded cell projection cytoplasm
0.47	GO:0005815	microtubule organizing center
0.37	GO:1903561	extracellular vesicle
0.33	GO:0005634	nucleus

tr|T1G1V9|T1G1V9_HELRO
Uncharacterized protein
Search

tr|T1G1W0|T1G1W0_HELRO
Uncharacterized protein
Search

0.45	GO:0060271	cilium assembly
0.40	GO:0097205	renal filtration
0.40	GO:0010842	retina layer formation
0.40	GO:0048793	pronephros development
0.39	GO:0001843	neural tube closure
0.39	GO:0007369	gastrulation

0.84	GO:0034464	BBSome
0.30	GO:0031224	intrinsic component of membrane

tr|T1G1W1|T1G1W1_HELRO
Uncharacterized protein
Search

GPHN

0.86	Gephyrin b

0.78	GO:0032324	molybdopterin cofactor biosynthetic process
0.73	GO:0006777	Mo-molybdopterin cofactor biosynthetic process
0.58	GO:0072578	neurotransmitter-gated ion channel clustering
0.56	GO:0001941	postsynaptic membrane organization
0.47	GO:0010038	response to metal ion
0.45	GO:0018315	molybdenum incorporation into molybdenum-molybdopterin complex
0.38	GO:0055114	oxidation-reduction process
0.38	GO:0098970	postsynaptic neurotransmitter receptor diffusion trapping
0.38	GO:0007529	establishment of synaptic specificity at neuromuscular junction
0.36	GO:0098880	maintenance of postsynaptic specialization structure

0.48	GO:0008940	nitrate reductase activity
0.47	GO:0043546	molybdopterin cofactor binding
0.44	GO:0061598	molybdopterin adenylyltransferase activity
0.44	GO:0061599	molybdopterin molybdotransferase activity
0.36	GO:0098879	structural constituent of postsynaptic specialization
0.35	GO:0005515	protein binding
0.35	GO:0060090	molecular adaptor activity
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0008144	drug binding

0.49	GO:0030425	dendrite
0.48	GO:0045211	postsynaptic membrane
0.37	GO:0060077	inhibitory synapse
0.37	GO:0030054	cell junction
0.36	GO:0099572	postsynaptic specialization
0.36	GO:0043025	neuronal cell body
0.36	GO:0005856	cytoskeleton
0.36	GO:0019897	extrinsic component of plasma membrane
0.35	GO:0005737	cytoplasm
0.34	GO:0009898	cytoplasmic side of plasma membrane

0.48

EC:1.7.99.4

GO:0008940

tr|T1G1W2|T1G1W2_HELRO
Uncharacterized protein
Search

tr|T1G1W3|T1G1W3_HELRO
Uncharacterized protein
Search

tr|T1G1W4|T1G1W4_HELRO
Uncharacterized protein
Search

RTN4IP1

0.65	Zinc-binding oxidoreductase

0.53	GO:0055114	oxidation-reduction process
0.43	GO:0016319	mushroom body development
0.39	GO:0050773	regulation of dendrite development
0.35	GO:0010842	retina layer formation
0.34	GO:0042462	eye photoreceptor cell development
0.33	GO:0099139	cheating during chimeric sorocarp development

0.55	GO:0008270	zinc ion binding
0.54	GO:0016491	oxidoreductase activity
0.33	GO:0003924	GTPase activity
0.33	GO:0005515	protein binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0043168	anion binding
0.32	GO:0072341	modified amino acid binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0016740	transferase activity

0.54	GO:0005739	mitochondrion
0.47	GO:0031968	organelle outer membrane
0.30	GO:0031224	intrinsic component of membrane

0.54

GO:0016491

tr|T1G1W5|T1G1W5_HELRO
Uncharacterized protein
Search

0.64	Pleckstrin homology domain containing protein (Fragment)

tr|T1G1W6|T1G1W6_HELRO
Poly [ADP-ribose] polymerase
Search

0.54	Poly [ADP-ribose] polymerase

0.35	GO:0045071	negative regulation of viral genome replication
0.35	GO:0061014	positive regulation of mRNA catabolic process
0.34	GO:0009615	response to virus

0.82	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.46	GO:0046872	metal ion binding
0.34	GO:0045296	cadherin binding
0.33	GO:0003723	RNA binding

0.33

GO:0005829

cytosol

0.82

GO:0003950

tr|T1G1W7|T1G1W7_HELRO
Uncharacterized protein
Search

0.46	Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase

0.53	GO:0055114	oxidation-reduction process
0.44	GO:0019310	inositol catabolic process
0.39	GO:0042843	D-xylose catabolic process

0.54

GO:0016491

oxidoreductase activity

0.54

GO:0016491

tr|T1G1W8|T1G1W8_HELRO
Uncharacterized protein
Search

tr|T1G1W9|T1G1W9_HELRO
Uncharacterized protein
Search

DHX37

0.91	DEAH (Asp-Glu-Ala-His) box polypeptide 37

0.44	GO:0048026	positive regulation of mRNA splicing, via spliceosome
0.40	GO:0006396	RNA processing
0.37	GO:0042274	ribosomal small subunit biogenesis
0.37	GO:0016072	rRNA metabolic process

0.67	GO:0004386	helicase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0003676	nucleic acid binding
0.43	GO:0008186	RNA-dependent ATPase activity
0.40	GO:0140098	catalytic activity, acting on RNA

0.44	GO:0005730	nucleolus
0.37	GO:0032040	small-subunit processome
0.36	GO:0005737	cytoplasm
0.33	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1G1X0|T1G1X0_HELRO
Uncharacterized protein
Search

SLC12A2

0.80	Bumetanide-sensitive Na-K-Cl cotransporter

0.75	GO:1902476	chloride transmembrane transport
0.55	GO:0070634	transepithelial ammonium transport
0.54	GO:0030321	transepithelial chloride transport
0.50	GO:0072488	ammonium transmembrane transport
0.42	GO:0045795	positive regulation of cell volume
0.40	GO:0007214	gamma-aminobutyric acid signaling pathway
0.39	GO:0006972	hyperosmotic response
0.39	GO:0007568	aging
0.39	GO:0060763	mammary duct terminal end bud growth
0.38	GO:0006814	sodium ion transport

0.83	GO:0015377	cation:chloride symporter activity
0.50	GO:0008519	ammonium transmembrane transporter activity
0.49	GO:0019901	protein kinase binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.46	GO:0016324	apical plasma membrane
0.38	GO:0016323	basolateral plasma membrane
0.37	GO:0070062	extracellular exosome
0.33	GO:0005887	integral component of plasma membrane

0.33

GO:0004553

tr|T1G1X1|T1G1X1_HELRO
Uncharacterized protein
Search

BDHA

0.59	D-beta-hydroxybutyrate dehydrogenase

0.52

GO:0055114

oxidation-reduction process

0.82

GO:0003858

3-hydroxybutyrate dehydrogenase activity

0.82	EC:1.1.1.30	GO:0003858
0.82	KEGG:R01361	GO:0003858

tr|T1G1X2|T1G1X2_HELRO
Uncharacterized protein
Search

tr|T1G1X3|T1G1X3_HELRO
Uncharacterized protein
Search

0.67	Homeobox protein Nkx-2.4

0.70	GO:1903779	regulation of cardiac conduction
0.68	GO:0060048	cardiac muscle contraction
0.66	GO:0007507	heart development
0.59	GO:0060037	pharyngeal system development
0.58	GO:0006357	regulation of transcription by RNA polymerase II
0.57	GO:0014706	striated muscle tissue development
0.56	GO:0051146	striated muscle cell differentiation
0.56	GO:0048568	embryonic organ development
0.55	GO:0035295	tube development
0.55	GO:0014855	striated muscle cell proliferation

0.65	GO:0043565	sequence-specific DNA binding
0.53	GO:0003700	DNA binding transcription factor activity
0.49	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.48	GO:0001012	RNA polymerase II regulatory region DNA binding
0.47	GO:0003682	chromatin binding
0.46	GO:0001104	RNA polymerase II transcription cofactor activity
0.46	GO:0003690	double-stranded DNA binding
0.45	GO:0042803	protein homodimerization activity
0.45	GO:0008134	transcription factor binding
0.45	GO:0046982	protein heterodimerization activity

0.61	GO:0005634	nucleus
0.47	GO:0005667	transcription factor complex
0.45	GO:0032993	protein-DNA complex
0.40	GO:0044446	intracellular organelle part
0.36	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1G1X4|T1G1X4_HELRO
Uncharacterized protein
Search

0.40	Long-chain-fatty-acid--CoA ligase 4

0.50	GO:0061502	early endosome to recycling endosome transport
0.49	GO:0030510	regulation of BMP signaling pathway
0.49	GO:0010890	positive regulation of sequestering of triglyceride
0.48	GO:0045886	negative regulation of synaptic growth at neuromuscular junction
0.48	GO:0003002	regionalization
0.46	GO:0001676	long-chain fatty acid metabolic process
0.46	GO:0090101	negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
0.46	GO:0090288	negative regulation of cellular response to growth factor stimulus
0.46	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process
0.45	GO:0007411	axon guidance

0.49	GO:0016874	ligase activity
0.34	GO:0019901	protein kinase binding
0.34	GO:0019904	protein domain specific binding
0.33	GO:0016758	transferase activity, transferring hexosyl groups

0.45	GO:0030424	axon
0.43	GO:0005783	endoplasmic reticulum
0.42	GO:0042579	microbody
0.42	GO:0005829	cytosol
0.36	GO:0005811	lipid droplet
0.35	GO:0044233	ER-mitochondrion membrane contact site
0.34	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0005794	Golgi apparatus
0.33	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.49

GO:0016874

tr|T1G1X5|T1G1X5_HELRO
Eukaryotic translation initiation factor 3 subunit E
Search

EIF3E

0.69	Eukaryotic translation initiation factor 3 subunit E-A

0.73	GO:0001731	formation of translation preinitiation complex
0.71	GO:0006446	regulation of translational initiation
0.54	GO:1902416	positive regulation of mRNA binding
0.51	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.48	GO:0045727	positive regulation of translation
0.34	GO:0017148	negative regulation of translation

0.73	GO:0003743	translation initiation factor activity
0.51	GO:0047485	protein N-terminus binding
0.50	GO:0045296	cadherin binding

0.78	GO:0005852	eukaryotic translation initiation factor 3 complex
0.72	GO:0016282	eukaryotic 43S preinitiation complex
0.72	GO:0033290	eukaryotic 48S preinitiation complex
0.57	GO:0005634	nucleus
0.45	GO:0005829	cytosol
0.45	GO:0043233	organelle lumen
0.41	GO:0044446	intracellular organelle part
0.34	GO:0070062	extracellular exosome
0.33	GO:0005694	chromosome
0.30	GO:0016020	membrane

tr|T1G1X6|T1G1X6_HELRO
Uncharacterized protein
Search

tr|T1G1X7|T1G1X7_HELRO
Uncharacterized protein
Search

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.38	GO:0030154	cell differentiation
0.37	GO:0060811	intracellular mRNA localization involved in anterior/posterior axis specification
0.37	GO:0007028	cytoplasm organization
0.37	GO:0008358	maternal determination of anterior/posterior axis, embryo
0.36	GO:0010821	regulation of mitochondrion organization
0.36	GO:0021700	developmental maturation
0.36	GO:0007292	female gamete generation

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.36	GO:0003714	transcription corepressor activity

0.61

GO:0005634

nucleus

tr|T1G1X8|T1G1X8_HELRO
Uncharacterized protein
Search

0.54	Mitochondrial ribosomal protein L16

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.39	GO:0015889	cobalamin transport
0.33	GO:0043624	cellular protein complex disassembly

0.66	GO:0019843	rRNA binding
0.64	GO:0003735	structural constituent of ribosome
0.38	GO:0031419	cobalamin binding
0.33	GO:0004386	helicase activity
0.32	GO:0046872	metal ion binding

0.61	GO:0005840	ribosome
0.48	GO:0005759	mitochondrial matrix
0.33	GO:0031966	mitochondrial membrane
0.33	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1G1X9|T1G1X9_HELRO
Uncharacterized protein
Search

0.88	HMG box containing protein 2

0.58	GO:0007530	sex determination
0.53	GO:0007548	sex differentiation
0.51	GO:1903506	regulation of nucleic acid-templated transcription
0.51	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.51	GO:0010468	regulation of gene expression
0.50	GO:0030154	cell differentiation
0.50	GO:0007275	multicellular organism development
0.43	GO:0006351	transcription, DNA-templated
0.36	GO:1902679	negative regulation of RNA biosynthetic process
0.35	GO:0060324	face development

0.55	GO:0003677	DNA binding
0.52	GO:0005516	calmodulin binding
0.44	GO:0140110	transcription regulator activity
0.36	GO:0001067	regulatory region nucleic acid binding
0.35	GO:0046982	protein heterodimerization activity

0.61	GO:0005634	nucleus
0.49	GO:0031974	membrane-enclosed lumen
0.44	GO:0044446	intracellular organelle part
0.35	GO:0005667	transcription factor complex
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1G1Y0|T1G1Y0_HELRO
Histone-lysine N-methyltransferase, H3 lysine-79 specific
Search

0.42	Histone-lysine N-methyltransferase, H3 lysine-79 specific

0.85	GO:0034729	histone H3-K79 methylation
0.73	GO:0051726	regulation of cell cycle
0.63	GO:0006342	chromatin silencing
0.52	GO:2000677	regulation of transcription regulatory region DNA binding
0.49	GO:0046425	regulation of JAK-STAT cascade
0.47	GO:0008284	positive regulation of cell proliferation
0.46	GO:0045944	positive regulation of transcription by RNA polymerase II
0.44	GO:0060729	intestinal epithelial structure maintenance
0.42	GO:0060070	canonical Wnt signaling pathway
0.39	GO:0006281	DNA repair

0.85	GO:0031151	histone methyltransferase activity (H3-K79 specific)
0.37	GO:0008134	transcription factor binding
0.34	GO:0004222	metalloendopeptidase activity
0.33	GO:0008080	N-acetyltransferase activity
0.32	GO:0046872	metal ion binding
0.32	GO:0003677	DNA binding

0.61	GO:0005634	nucleus
0.43	GO:0000781	chromosome, telomeric region
0.43	GO:0031974	membrane-enclosed lumen
0.40	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0004222

tr|T1G1Y1|T1G1Y1_HELRO
Uncharacterized protein
Search

0.74	GO:0003779	actin binding
0.34	GO:0032403	protein complex binding

0.30

GO:0031224

intrinsic component of membrane

tr|T1G1Y2|T1G1Y2_HELRO
Uncharacterized protein
Search

HELQ

0.61	Helicase POLQ

0.47	GO:0000724	double-strand break repair via homologous recombination
0.46	GO:0009951	polarity specification of dorsal/ventral axis
0.46	GO:0009949	polarity specification of anterior/posterior axis
0.46	GO:0007294	germarium-derived oocyte fate determination
0.46	GO:0016321	female meiosis chromosome segregation
0.46	GO:0030717	karyosome formation
0.45	GO:0010501	RNA secondary structure unwinding
0.44	GO:0008298	intracellular mRNA localization
0.34	GO:0032392	DNA geometric change
0.34	GO:0000712	resolution of meiotic recombination intermediates

0.57	GO:0004386	helicase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0003676	nucleic acid binding
0.43	GO:0008186	RNA-dependent ATPase activity
0.39	GO:0140098	catalytic activity, acting on RNA
0.35	GO:0043142	single-stranded DNA-dependent ATPase activity
0.34	GO:0051117	ATPase binding
0.33	GO:0005509	calcium ion binding

0.42	GO:0005730	nucleolus
0.36	GO:0005737	cytoplasm
0.35	GO:0017117	single-stranded DNA-dependent ATP-dependent DNA helicase complex
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:3.2

GO:0016798

tr|T1G1Y3|T1G1Y3_HELRO
Uncharacterized protein
Search

0.89	Cholinergic receptor nicotinic alpha 4 subunit

0.76	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.49	GO:0035094	response to nicotine
0.47	GO:0007271	synaptic transmission, cholinergic
0.46	GO:0060080	inhibitory postsynaptic potential
0.46	GO:0050433	regulation of catecholamine secretion
0.45	GO:0035640	exploration behavior
0.45	GO:0051899	membrane depolarization
0.45	GO:0007585	respiratory gaseous exchange
0.45	GO:0019233	sensory perception of pain

0.79	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0004888	transmembrane signaling receptor activity
0.43	GO:0042166	acetylcholine binding
0.33	GO:0005515	protein binding
0.33	GO:0022850	serotonin-gated cation-selective channel activity
0.32	GO:0008270	zinc ion binding
0.32	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups

0.75	GO:0045211	postsynaptic membrane
0.71	GO:0030054	cell junction
0.49	GO:0005892	acetylcholine-gated channel complex
0.44	GO:0009897	external side of plasma membrane
0.42	GO:0043204	perikaryon
0.41	GO:0030425	dendrite
0.41	GO:0030424	axon
0.34	GO:0005737	cytoplasm
0.33	GO:0032589	neuron projection membrane
0.33	GO:0016324	apical plasma membrane

0.32

EC:2.3.1

GO:0016747

tr|T1G1Y4|T1G1Y4_HELRO
Uncharacterized protein
Search

0.53	Angiopoietin-related protein 7

0.59	GO:0001525	angiogenesis
0.57	GO:0043066	negative regulation of apoptotic process
0.48	GO:0042060	wound healing
0.47	GO:0007599	hemostasis
0.47	GO:0050817	coagulation
0.46	GO:0072376	protein activation cascade
0.45	GO:2000351	regulation of endothelial cell apoptotic process
0.45	GO:0045087	innate immune response
0.45	GO:0051005	negative regulation of lipoprotein lipase activity
0.45	GO:0001775	cell activation

0.55	GO:0033691	sialic acid binding
0.45	GO:0005509	calcium ion binding
0.45	GO:0030674	protein binding, bridging
0.45	GO:0005102	receptor binding
0.44	GO:0030246	carbohydrate binding
0.43	GO:0004857	enzyme inhibitor activity
0.40	GO:0042802	identical protein binding
0.40	GO:0038187	pattern recognition receptor activity
0.38	GO:0061135	endopeptidase regulator activity
0.37	GO:0004222	metalloendopeptidase activity

0.57	GO:0005615	extracellular space
0.45	GO:0005581	collagen trimer
0.41	GO:0031232	extrinsic component of external side of plasma membrane
0.37	GO:0031091	platelet alpha granule
0.30	GO:0016021	integral component of membrane

0.37

GO:0004222

tr|T1G1Y5|T1G1Y5_HELRO
Uncharacterized protein
Search

tr|T1G1Y6|T1G1Y6_HELRO
Uncharacterized protein
Search

tr|T1G1Y7|T1G1Y7_HELRO
Uncharacterized protein
Search

NDOR1

0.62	NADPH-dependent diflavin oxidoreductase 1

0.64	GO:0016226	iron-sulfur cluster assembly
0.53	GO:0036245	cellular response to menadione
0.53	GO:0055114	oxidation-reduction process
0.48	GO:0008219	cell death
0.45	GO:0009793	embryo development ending in seed dormancy
0.40	GO:0000103	sulfate assimilation
0.40	GO:0019344	cysteine biosynthetic process
0.39	GO:0070814	hydrogen sulfide biosynthetic process
0.34	GO:0006091	generation of precursor metabolites and energy

0.74	GO:0003958	NADPH-hemoprotein reductase activity
0.70	GO:0010181	FMN binding
0.61	GO:0050661	NADP binding
0.59	GO:0050660	flavin adenine dinucleotide binding
0.45	GO:0043546	molybdopterin cofactor binding
0.43	GO:0004783	sulfite reductase (NADPH) activity
0.42	GO:0051536	iron-sulfur cluster binding
0.38	GO:0046872	metal ion binding
0.35	GO:0008940	nitrate reductase activity
0.35	GO:0042602	riboflavin reductase (NADPH) activity

0.54	GO:0048471	perinuclear region of cytoplasm
0.48	GO:0045111	intermediate filament cytoskeleton
0.45	GO:0005829	cytosol
0.45	GO:0005634	nucleus
0.34	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.74	EC:1.6.2.4	GO:0003958
0.35	KEGG:R05707	GO:0042602

tr|T1G1Y8|T1G1Y8_HELRO
Uncharacterized protein
Search

0.40	Glutaredoxin GRX

0.69	GO:0045454	cell redox homeostasis
0.61	GO:0022900	electron transport chain
0.38	GO:0006886	intracellular protein transport
0.37	GO:0003147	neural crest cell migration involved in heart formation
0.37	GO:0080058	protein deglutathionylation
0.37	GO:0009636	response to toxic substance
0.37	GO:0070887	cellular response to chemical stimulus
0.36	GO:0010035	response to inorganic substance
0.36	GO:0001944	vasculature development
0.35	GO:0007417	central nervous system development

0.72	GO:0015035	protein disulfide oxidoreductase activity
0.62	GO:0009055	electron transfer activity
0.38	GO:0004791	thioredoxin-disulfide reductase activity
0.36	GO:0050660	flavin adenine dinucleotide binding
0.33	GO:0046872	metal ion binding
0.33	GO:0033743	peptide-methionine (R)-S-oxide reductase activity
0.33	GO:0004222	metalloendopeptidase activity
0.33	GO:0042802	identical protein binding
0.33	GO:0051537	2 iron, 2 sulfur cluster binding
0.33	GO:0003723	RNA binding

0.39	GO:0030176	integral component of endoplasmic reticulum membrane
0.37	GO:0048046	apoplast
0.37	GO:0005829	cytosol
0.36	GO:0005773	vacuole
0.36	GO:0005794	Golgi apparatus
0.34	GO:0005739	mitochondrion
0.34	GO:0005886	plasma membrane
0.33	GO:0005654	nucleoplasm

0.38	EC:1.8.1.9	GO:0004791
0.38	KEGG:R02016	GO:0004791

tr|T1G1Y9|T1G1Y9_HELRO
Uncharacterized protein
Search

tr|T1G1Z0|T1G1Z0_HELRO
Uncharacterized protein
Search

0.41	Glutaredoxin (thioltransferase)

0.69	GO:0045454	cell redox homeostasis
0.61	GO:0022900	electron transport chain
0.49	GO:0045838	positive regulation of membrane potential
0.49	GO:2000651	positive regulation of sodium ion transmembrane transporter activity
0.46	GO:0080058	protein deglutathionylation
0.45	GO:0003147	neural crest cell migration involved in heart formation
0.41	GO:0001944	vasculature development
0.41	GO:0007417	central nervous system development
0.40	GO:0046688	response to copper ion
0.40	GO:0055070	copper ion homeostasis

0.72	GO:0015035	protein disulfide oxidoreductase activity
0.62	GO:0009055	electron transfer activity
0.47	GO:0047485	protein N-terminus binding
0.37	GO:0047139	glutathione-homocystine transhydrogenase activity
0.36	GO:0015038	glutathione disulfide oxidoreductase activity
0.36	GO:0016740	transferase activity
0.34	GO:0019153	protein-disulfide reductase (glutathione) activity
0.34	GO:0033743	peptide-methionine (R)-S-oxide reductase activity
0.33	GO:0004222	metalloendopeptidase activity
0.32	GO:0046872	metal ion binding

0.40	GO:0044444	cytoplasmic part
0.39	GO:0005634	nucleus
0.38	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.37	GO:0031984	organelle subcompartment
0.35	GO:0070062	extracellular exosome
0.34	GO:0043025	neuronal cell body
0.34	GO:0030425	dendrite
0.34	GO:0031970	organelle envelope lumen
0.30	GO:0016021	integral component of membrane

0.37	EC:1.8.4.1	GO:0047139
0.34	KEGG:R07607	GO:0033743

tr|T1G1Z1|T1G1Z1_HELRO
Uncharacterized protein
Search

0.67	Myosuppressin receptor

0.71

GO:0007186

G-protein coupled receptor signaling pathway

0.79

GO:0008528

G-protein coupled peptide receptor activity

0.30

GO:0044425

membrane part

tr|T1G1Z2|T1G1Z2_HELRO
Uncharacterized protein
Search

0.51	Diadenosine and diphosphoinositol polyphosphate phosphohydrolase

0.57	GO:0071543	diphosphoinositol polyphosphate metabolic process
0.51	GO:1901909	diadenosine hexaphosphate catabolic process
0.51	GO:1901907	diadenosine pentaphosphate catabolic process
0.51	GO:1901910	adenosine 5'-(hexahydrogen pentaphosphate) metabolic process
0.50	GO:0009169	purine ribonucleoside monophosphate catabolic process
0.48	GO:0071545	inositol phosphate catabolic process
0.48	GO:0009154	purine ribonucleotide catabolic process
0.45	GO:0046626	regulation of insulin receptor signaling pathway
0.44	GO:0055088	lipid homeostasis
0.43	GO:0042593	glucose homeostasis

0.61	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity
0.51	GO:0034431	bis(5'-adenosyl)-hexaphosphatase activity
0.51	GO:0034432	bis(5'-adenosyl)-pentaphosphatase activity
0.50	GO:0050072	m7G(5')pppN diphosphatase activity
0.50	GO:0000298	endopolyphosphatase activity
0.43	GO:0052848	inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity
0.43	GO:0052844	inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity
0.43	GO:0052845	inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity
0.43	GO:0052846	inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity
0.43	GO:0052847	inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity

0.45	GO:0005829	cytosol
0.43	GO:0005634	nucleus
0.36	GO:0070062	extracellular exosome
0.33	GO:0005882	intermediate filament
0.33	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

0.61	EC:3.6.1.52	GO:0008486
0.61	KEGG:R05777	GO:0008486

tr|T1G1Z3|T1G1Z3_HELRO
Uncharacterized protein
Search

tr|T1G1Z4|T1G1Z4_HELRO
Uncharacterized protein
Search

SNRPD1

0.76	Small nuclear ribonucleoprotein D1 polypeptide

0.81	GO:0000387	spliceosomal snRNP assembly
0.46	GO:0000245	spliceosomal complex assembly
0.40	GO:0007507	heart development
0.35	GO:1901800	positive regulation of proteasomal protein catabolic process
0.35	GO:0030163	protein catabolic process
0.34	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.34	GO:0070647	protein modification by small protein conjugation or removal
0.34	GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.34	GO:0006378	mRNA polyadenylation
0.34	GO:0001756	somitogenesis

0.39	GO:0003723	RNA binding
0.38	GO:1990446	U1 snRNP binding
0.36	GO:0036402	proteasome-activating ATPase activity
0.33	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.33	GO:0008270	zinc ion binding
0.33	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005515	protein binding

0.60	GO:0030529	intracellular ribonucleoprotein complex
0.60	GO:0019013	viral nucleocapsid
0.54	GO:0034715	pICln-Sm protein complex
0.53	GO:0034719	SMN-Sm protein complex
0.50	GO:0034709	methylosome
0.46	GO:0044428	nuclear part
0.44	GO:0005829	cytosol
0.34	GO:0031974	membrane-enclosed lumen
0.34	GO:0005813	centrosome
0.33	GO:0031410	cytoplasmic vesicle

0.33	EC:3.4.19.12	GO:0036459
0.33	KEGG:R03876	GO:0004842

tr|T1G1Z5|T1G1Z5_HELRO
Uncharacterized protein
Search

GHRHRA

0.85	Growth hormone releasing hormone receptor a (Fragment)

0.71	GO:0007166	cell surface receptor signaling pathway
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.56	GO:0060133	somatotropin secreting cell development
0.55	GO:0030252	growth hormone secretion
0.55	GO:0040018	positive regulation of multicellular organism growth
0.55	GO:0060124	positive regulation of growth hormone secretion
0.54	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway
0.54	GO:0007595	lactation
0.53	GO:0019933	cAMP-mediated signaling
0.53	GO:0032868	response to insulin

0.72	GO:0004930	G-protein coupled receptor activity
0.54	GO:0017046	peptide hormone binding
0.51	GO:0019838	growth factor binding

0.53	GO:0005640	nuclear outer membrane
0.53	GO:0005886	plasma membrane
0.52	GO:0016363	nuclear matrix
0.51	GO:0005637	nuclear inner membrane
0.50	GO:0030141	secretory granule
0.49	GO:0009986	cell surface
0.30	GO:0016021	integral component of membrane

tr|T1G1Z6|T1G1Z6_HELRO
Uncharacterized protein
Search

tr|T1G1Z7|T1G1Z7_HELRO
Uncharacterized protein
Search

0.74	Junctophilin-1

0.46	GO:0007517	muscle organ development
0.45	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity
0.44	GO:0060402	calcium ion transport into cytosol
0.44	GO:0051283	negative regulation of sequestering of calcium ion
0.42	GO:0035640	exploration behavior
0.42	GO:0070588	calcium ion transmembrane transport
0.41	GO:0048168	regulation of neuronal synaptic plasticity
0.41	GO:0050885	neuromuscular process controlling balance
0.41	GO:0007613	memory
0.41	GO:0007612	learning

0.48	GO:0008307	structural constituent of muscle
0.44	GO:0015278	calcium-release channel activity
0.39	GO:0010314	phosphatidylinositol-5-phosphate binding
0.39	GO:0070300	phosphatidic acid binding
0.39	GO:0001786	phosphatidylserine binding
0.39	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.38	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding
0.38	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.38	GO:0070273	phosphatidylinositol-4-phosphate binding
0.38	GO:0032266	phosphatidylinositol-3-phosphate binding

0.78	GO:0030314	junctional membrane complex
0.50	GO:0014701	junctional sarcoplasmic reticulum membrane
0.48	GO:0030018	Z disc
0.43	GO:0005654	nucleoplasm
0.40	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1G1Z8|T1G1Z8_HELRO
Uncharacterized protein
Search

SLC4A11

0.91	Sodium bicarbonate transporter protein 11

0.69	GO:0015698	inorganic anion transport
0.50	GO:0015701	bicarbonate transport
0.49	GO:0042044	fluid transport
0.49	GO:0035725	sodium ion transmembrane transport
0.48	GO:0030003	cellular cation homeostasis
0.47	GO:0006855	drug transmembrane transport
0.46	GO:0098656	anion transmembrane transport
0.44	GO:0006885	regulation of pH
0.41	GO:1902600	hydrogen ion transmembrane transport
0.33	GO:0006526	arginine biosynthetic process

0.83	GO:0005452	inorganic anion exchanger activity
0.52	GO:0046715	active borate transmembrane transporter activity
0.50	GO:0015106	bicarbonate transmembrane transporter activity
0.50	GO:0015252	proton channel activity
0.48	GO:0005272	sodium channel activity
0.43	GO:0046983	protein dimerization activity
0.36	GO:0015301	anion:anion antiporter activity
0.35	GO:0015293	symporter activity
0.33	GO:0004055	argininosuccinate synthase activity
0.32	GO:0032559	adenyl ribonucleotide binding

0.40	GO:0005887	integral component of plasma membrane
0.34	GO:0016323	basolateral plasma membrane

0.33

EC:6.3.4.5

GO:0004055

tr|T1G1Z9|T1G1Z9_HELRO
Uncharacterized protein
Search

ALG13

0.37	Glycosyltransferase

0.48	GO:0006488	dolichol-linked oligosaccharide biosynthetic process
0.35	GO:0070084	protein initiator methionine removal
0.35	GO:0006508	proteolysis
0.34	GO:0070897	DNA-templated transcriptional preinitiation complex assembly
0.34	GO:0019083	viral transcription
0.34	GO:0001172	transcription, RNA-templated
0.32	GO:0006355	regulation of transcription, DNA-templated

0.69	GO:0016758	transferase activity, transferring hexosyl groups
0.46	GO:0008194	UDP-glycosyltransferase activity
0.35	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.35	GO:0070006	metalloaminopeptidase activity
0.34	GO:0005515	protein binding
0.34	GO:0003968	RNA-directed 5'-3' RNA polymerase activity
0.33	GO:0003723	RNA binding
0.33	GO:0046872	metal ion binding

0.50	GO:0043541	UDP-N-acetylglucosamine transferase complex
0.34	GO:0042406	extrinsic component of endoplasmic reticulum membrane
0.32	GO:0005829	cytosol

0.69

GO:0016758

tr|T1G200|T1G200_HELRO
Uncharacterized protein
Search

TMEM14C

0.60	Transmembrane protein 14Cb

0.30

GO:0044425

membrane part

tr|T1G201|T1G201_HELRO
Uncharacterized protein
Search

NDUFS2

0.85	NADH dehydrogenase-ubiquinone Fe-S protein 2

0.53	GO:0055114	oxidation-reduction process
0.46	GO:0006979	response to oxidative stress
0.43	GO:0006119	oxidative phosphorylation
0.34	GO:0032981	mitochondrial respiratory chain complex I assembly
0.33	GO:0007166	cell surface receptor signaling pathway

0.72	GO:0048038	quinone binding
0.68	GO:0051287	NAD binding
0.67	GO:0016651	oxidoreductase activity, acting on NAD(P)H
0.48	GO:0031625	ubiquitin protein ligase binding
0.38	GO:0051539	4 iron, 4 sulfur cluster binding
0.35	GO:0046872	metal ion binding
0.33	GO:0004888	transmembrane signaling receptor activity
0.33	GO:0009055	electron transfer activity

0.50	GO:0005747	mitochondrial respiratory chain complex I
0.45	GO:0005654	nucleoplasm
0.34	GO:0005759	mitochondrial matrix
0.30	GO:0031224	intrinsic component of membrane

0.67

EC:1.6

GO:0016651

tr|T1G202|T1G202_HELRO
Uncharacterized protein
Search

0.51	Electroneutral potassium-chloride cotransporter 1

0.86	GO:0071477	cellular hypotonic salinity response
0.77	GO:1902476	chloride transmembrane transport
0.45	GO:0007638	mechanosensory behavior
0.41	GO:0007268	chemical synaptic transmission
0.40	GO:0071805	potassium ion transmembrane transport
0.38	GO:0003333	amino acid transmembrane transport
0.34	GO:0034975	protein folding in endoplasmic reticulum

0.85	GO:0015379	potassium:chloride symporter activity
0.42	GO:0022820	potassium ion symporter activity
0.38	GO:0015171	amino acid transmembrane transporter activity

0.67	GO:0005887	integral component of plasma membrane
0.43	GO:0043025	neuronal cell body
0.43	GO:0030424	axon
0.34	GO:0072546	ER membrane protein complex

tr|T1G203|T1G203_HELRO
Uncharacterized protein
Search

PICK1

0.91	PRKCA-binding protein isoform B

0.53	GO:0015844	monoamine transport
0.52	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway
0.46	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation
0.41	GO:0097062	dendritic spine maintenance
0.41	GO:0060292	long term synaptic depression
0.41	GO:0002092	positive regulation of receptor internalization
0.40	GO:0051126	negative regulation of actin nucleation
0.40	GO:0042149	cellular response to glucose starvation
0.40	GO:0021782	glial cell development
0.40	GO:0036294	cellular response to decreased oxygen levels

0.77	GO:0019904	protein domain specific binding
0.52	GO:0008022	protein C-terminus binding
0.46	GO:0019899	enzyme binding
0.40	GO:0071933	Arp2/3 complex binding
0.39	GO:0051015	actin filament binding
0.37	GO:0016301	kinase activity
0.37	GO:0001664	G-protein coupled receptor binding
0.36	GO:0042802	identical protein binding
0.35	GO:0035255	ionotropic glutamate receptor binding
0.34	GO:0046872	metal ion binding

0.53	GO:0042734	presynaptic membrane
0.52	GO:0016235	aggresome
0.45	GO:0005829	cytosol
0.43	GO:0005739	mitochondrion
0.40	GO:0014069	postsynaptic density
0.39	GO:0045211	postsynaptic membrane
0.39	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0043005	neuron projection
0.38	GO:0030054	cell junction
0.37	GO:0005856	cytoskeleton

tr|T1G204|T1G204_HELRO
Uncharacterized protein
Search

tr|T1G205|T1G205_HELRO
Uncharacterized protein
Search

RPL6

0.61	Large subunit ribosomal protein 6 (Fragment)

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.42	GO:0000027	ribosomal large subunit assembly
0.40	GO:0008340	determination of adult lifespan
0.38	GO:0031016	pancreas development
0.37	GO:0043009	chordate embryonic development
0.34	GO:0034613	cellular protein localization
0.34	GO:0045184	establishment of protein localization

0.64	GO:0003735	structural constituent of ribosome
0.38	GO:0003723	RNA binding
0.35	GO:0045296	cadherin binding
0.34	GO:0004385	guanylate kinase activity
0.33	GO:0008168	methyltransferase activity

0.61	GO:0005840	ribosome
0.42	GO:0044445	cytosolic part
0.38	GO:0044446	intracellular organelle part
0.35	GO:0005844	polysome
0.34	GO:0030123	AP-3 adaptor complex
0.34	GO:0036464	cytoplasmic ribonucleoprotein granule
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0004385

tr|T1G206|T1G206_HELRO
Uncharacterized protein
Search

tr|T1G207|T1G207_HELRO
Uncharacterized protein
Search

DHX29

0.83	ATP-dependent RNA helicase Dhx29

0.70	GO:0045948	positive regulation of translational initiation
0.64	GO:0006413	translational initiation
0.41	GO:0006396	RNA processing

0.69	GO:0004004	ATP-dependent RNA helicase activity
0.63	GO:0003743	translation initiation factor activity
0.56	GO:0043024	ribosomal small subunit binding
0.53	GO:0045296	cadherin binding
0.52	GO:0032559	adenyl ribonucleotide binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0008270	zinc ion binding

0.52	GO:0016282	eukaryotic 43S preinitiation complex
0.44	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

tr|T1G208|T1G208_HELRO
Uncharacterized protein
Search

0.11	Pre-mRNA-splicing factor syf2 (Fragment)

0.73	GO:0007095	mitotic G2 DNA damage checkpoint
0.69	GO:0007369	gastrulation
0.67	GO:0048568	embryonic organ development
0.67	GO:0001701	in utero embryonic development
0.57	GO:0008380	RNA splicing
0.55	GO:0006397	mRNA processing
0.50	GO:0008284	positive regulation of cell proliferation

0.40	GO:0003723	RNA binding
0.38	GO:0005515	protein binding

0.79	GO:0071013	catalytic step 2 spliceosome
0.73	GO:0005684	U2-type spliceosomal complex
0.73	GO:0016607	nuclear speck
0.69	GO:0000974	Prp19 complex
0.68	GO:0071014	post-mRNA release spliceosomal complex

tr|T1G209|T1G209_HELRO
Uncharacterized protein
Search

0.63

GO:0044255

cellular lipid metabolic process

0.69

GO:0052689

carboxylic ester hydrolase activity

0.30

GO:0044425

membrane part

0.69	EC:3.1.1 EC:3.1.1.1	GO:0052689
0.69	KEGG:R00630	GO:0052689

tr|T1G210|T1G210_HELRO
Uncharacterized protein
Search

OPA1

0.83	Dynamin-like protein, mitochondrial isoform D

0.78	GO:0006915	apoptotic process
0.75	GO:0007005	mitochondrion organization
0.50	GO:0097749	membrane tubulation
0.47	GO:0090201	negative regulation of release of cytochrome c from mitochondria
0.47	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
0.47	GO:0048284	organelle fusion
0.47	GO:0090398	cellular senescence
0.45	GO:0007601	visual perception
0.45	GO:1905232	cellular response to L-glutamate
0.45	GO:0046039	GTP metabolic process

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.49	GO:1901612	cardiolipin binding
0.48	GO:0070300	phosphatidic acid binding
0.41	GO:0019900	kinase binding
0.40	GO:0008017	microtubule binding
0.35	GO:0000287	magnesium ion binding

0.61	GO:0005739	mitochondrion
0.45	GO:0031970	organelle envelope lumen
0.45	GO:0031968	organelle outer membrane
0.43	GO:0030425	dendrite
0.43	GO:0005654	nucleoplasm
0.42	GO:0005829	cytosol
0.41	GO:0031312	extrinsic component of organelle membrane
0.40	GO:0019866	organelle inner membrane
0.38	GO:1904115	axon cytoplasm
0.30	GO:0016021	integral component of membrane

tr|T1G211|T1G211_HELRO
Uncharacterized protein
Search

RAB8A

0.83	Putative rab subfamily protein of small gtpase

0.53	GO:0045046	protein import into peroxisome membrane
0.49	GO:0051640	organelle localization
0.49	GO:0072659	protein localization to plasma membrane
0.49	GO:0140029	exocytic process
0.49	GO:0022406	membrane docking
0.48	GO:0017157	regulation of exocytosis
0.48	GO:0019882	antigen processing and presentation
0.45	GO:0009306	protein secretion
0.44	GO:0035845	photoreceptor cell outer segment organization
0.43	GO:0048210	Golgi vesicle fusion to target membrane

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.54	GO:0019003	GDP binding
0.46	GO:0005102	receptor binding
0.42	GO:0031489	myosin V binding
0.39	GO:0030911	TPR domain binding
0.37	GO:0071532	ankyrin repeat binding
0.36	GO:0032794	GTPase activating protein binding
0.35	GO:0019901	protein kinase binding
0.34	GO:0017137	Rab GTPase binding

0.53	GO:0045335	phagocytic vesicle
0.51	GO:0098805	whole membrane
0.50	GO:0098588	bounding membrane of organelle
0.49	GO:0044438	microbody part
0.48	GO:0016604	nuclear body
0.48	GO:0030133	transport vesicle
0.48	GO:0005768	endosome
0.48	GO:0030141	secretory granule
0.48	GO:0005777	peroxisome
0.48	GO:0044433	cytoplasmic vesicle part

tr|T1G212|T1G212_HELRO
Uncharacterized protein
Search

CHN1

0.87	N-chimaerin

0.66	GO:0043087	regulation of GTPase activity
0.65	GO:0051345	positive regulation of hydrolase activity
0.63	GO:0035556	intracellular signal transduction
0.58	GO:0051056	regulation of small GTPase mediated signal transduction
0.51	GO:0008045	motor neuron axon guidance
0.50	GO:0050770	regulation of axonogenesis
0.40	GO:0021622	oculomotor nerve morphogenesis
0.39	GO:0021603	cranial nerve formation
0.38	GO:0015991	ATP hydrolysis coupled proton transport
0.38	GO:0048013	ephrin receptor signaling pathway

0.66	GO:0005096	GTPase activator activity
0.53	GO:0046872	metal ion binding
0.51	GO:0046875	ephrin receptor binding
0.42	GO:0001565	phorbol ester receptor activity
0.39	GO:0046961	proton-transporting ATPase activity, rotational mechanism
0.34	GO:0005070	SH3/SH2 adaptor activity
0.33	GO:0051082	unfolded protein binding

0.45	GO:0005622	intracellular
0.37	GO:0033178	proton-transporting two-sector ATPase complex, catalytic domain
0.33	GO:0071944	cell periphery
0.30	GO:0031224	intrinsic component of membrane

tr|T1G213|T1G213_HELRO
Uncharacterized protein
Search

KLHL5

0.87	Kelch like family member 5

0.65

GO:0016567

protein ubiquitination

0.65

GO:0004842

ubiquitin-protein transferase activity

0.73	GO:0031463	Cul3-RING ubiquitin ligase complex
0.57	GO:0005815	microtubule organizing center
0.30	GO:0031224	intrinsic component of membrane

0.65

GO:0004842

tr|T1G214|T1G214_HELRO
Synaptotagmin 16
Search

0.85	Putative ca2+-dependent phospholipid-binding protein synaptotagmin

0.71	GO:0006887	exocytosis
0.49	GO:0017158	regulation of calcium ion-dependent exocytosis
0.48	GO:0048489	synaptic vesicle transport
0.48	GO:0099504	synaptic vesicle cycle
0.48	GO:0006906	vesicle fusion
0.48	GO:0099643	signal release from synapse
0.48	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.45	GO:0006836	neurotransmitter transport
0.44	GO:0001505	regulation of neurotransmitter levels
0.34	GO:0046854	phosphatidylinositol phosphorylation

0.50	GO:0005543	phospholipid binding
0.48	GO:0019905	syntaxin binding
0.47	GO:0042803	protein homodimerization activity
0.47	GO:0030276	clathrin binding
0.47	GO:0046982	protein heterodimerization activity
0.43	GO:0005509	calcium ion binding
0.35	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity

0.39	GO:0005886	plasma membrane
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.35	EC:2.7.1.154	GO:0035005
0.35	KEGG:R05795	GO:0035005

tr|T1G215|T1G215_HELRO
Uncharacterized protein
Search

PNPLA4

0.97	Patatin like phospholipase domain containing 4

0.72	GO:0016042	lipid catabolic process
0.69	GO:0042572	retinol metabolic process
0.57	GO:0010898	positive regulation of triglyceride catabolic process
0.46	GO:0055088	lipid homeostasis
0.45	GO:0006641	triglyceride metabolic process
0.40	GO:0001889	liver development
0.40	GO:0044248	cellular catabolic process
0.34	GO:0010891	negative regulation of sequestering of triglyceride

0.73	GO:0050253	retinyl-palmitate esterase activity
0.71	GO:0004806	triglyceride lipase activity

0.46	GO:0005811	lipid droplet
0.42	GO:0005739	mitochondrion
0.33	GO:0005829	cytosol
0.33	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

0.73	EC:3.1.1	GO:0050253
0.73	KEGG:R02368	GO:0050253

tr|T1G216|T1G216_HELRO
Uncharacterized protein
Search

LYPLAL1

0.74	Lysophospholipase like 1

0.47	GO:0002084	protein depalmitoylation
0.36	GO:0042997	negative regulation of Golgi to plasma membrane protein transport
0.33	GO:0006631	fatty acid metabolic process
0.32	GO:0055114	oxidation-reduction process

0.51	GO:0016787	hydrolase activity
0.38	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.32	GO:0003677	DNA binding

0.44	GO:0005829	cytosol
0.35	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.51

GO:0016787

tr|T1G217|T1G217_HELRO
Uncharacterized protein
Search

0.38	GO:0016042	lipid catabolic process
0.37	GO:0006289	nucleotide-excision repair
0.36	GO:0035556	intracellular signal transduction
0.35	GO:0006351	transcription, DNA-templated

0.39	GO:0004435	phosphatidylinositol phospholipase C activity
0.36	GO:0004871	signal transducer activity
0.36	GO:0005515	protein binding
0.36	GO:0008270	zinc ion binding
0.34	GO:0003676	nucleic acid binding

0.68	GO:0005654	nucleoplasm
0.66	GO:0005829	cytosol
0.39	GO:0000439	core TFIIH complex
0.30	GO:0016020	membrane

0.39	EC:3.1.4.11	GO:0004435
0.39	KEGG:R03435	GO:0004435

tr|T1G218|T1G218_HELRO
Uncharacterized protein
Search

0.10	Calcium-binding EGF domain containing protein

0.78	GO:0007219	Notch signaling pathway
0.68	GO:0030154	cell differentiation
0.66	GO:0007275	multicellular organism development
0.65	GO:0050793	regulation of developmental process
0.52	GO:0045967	negative regulation of growth rate
0.49	GO:0046849	bone remodeling
0.49	GO:0046579	positive regulation of Ras protein signal transduction
0.48	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.48	GO:0007050	cell cycle arrest
0.46	GO:0006355	regulation of transcription, DNA-templated

0.70	GO:0005509	calcium ion binding
0.50	GO:0060089	molecular transducer activity
0.41	GO:0008270	zinc ion binding
0.37	GO:0051059	NF-kappaB binding
0.35	GO:0019899	enzyme binding
0.34	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.33	GO:0004871	signal transducer activity

0.46	GO:0043235	receptor complex
0.45	GO:0009986	cell surface
0.43	GO:0005654	nucleoplasm
0.43	GO:0005887	integral component of plasma membrane
0.35	GO:0005576	extracellular region
0.35	GO:0005929	cilium
0.34	GO:0005829	cytosol
0.34	GO:0000139	Golgi membrane
0.34	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0031982	vesicle

tr|T1G219|T1G219_HELRO
Uncharacterized protein
Search

0.30

GO:0044425

membrane part

tr|T1G220|T1G220_HELRO
Uncharacterized protein
Search

0.16	Actin-related protein 8

0.78	GO:0006338	chromatin remodeling
0.64	GO:0006310	DNA recombination
0.64	GO:0006281	DNA repair
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression

0.54	GO:0030554	adenyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.80

GO:0031011

Ino80 complex

tr|T1G221|T1G221_HELRO
Uncharacterized protein
Search

0.78	GO:0035023	regulation of Rho protein signal transduction
0.66	GO:0065009	regulation of molecular function
0.53	GO:0035556	intracellular signal transduction
0.39	GO:0007186	G-protein coupled receptor signaling pathway
0.36	GO:0006897	endocytosis
0.35	GO:0071802	negative regulation of podosome assembly
0.35	GO:1902219	negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress
0.35	GO:0071225	cellular response to muramyl dipeptide
0.35	GO:0060546	negative regulation of necroptotic process
0.35	GO:2001224	positive regulation of neuron migration

0.78	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.48	GO:0046872	metal ion binding
0.34	GO:0008092	cytoskeletal protein binding
0.34	GO:0048365	Rac GTPase binding
0.34	GO:0016301	kinase activity
0.33	GO:0008134	transcription factor binding
0.33	GO:0005096	GTPase activator activity
0.32	GO:0048037	cofactor binding

0.41	GO:0005622	intracellular
0.38	GO:0030054	cell junction
0.35	GO:0043228	non-membrane-bounded organelle
0.35	GO:0044422	organelle part
0.34	GO:0043198	dendritic shaft
0.34	GO:0032587	ruffle membrane
0.34	GO:0014069	postsynaptic density
0.34	GO:0043025	neuronal cell body
0.33	GO:0099512	supramolecular fiber
0.33	GO:0031982	vesicle

tr|T1G222|T1G222_HELRO
Uncharacterized protein
Search

GPB-1

0.74	Guanine nucleotide-binding protein subunit beta

0.61	GO:0007165	signal transduction
0.43	GO:0046662	regulation of oviposition
0.42	GO:0000132	establishment of mitotic spindle orientation
0.41	GO:0040013	negative regulation of locomotion
0.40	GO:0009792	embryo development ending in birth or egg hatching
0.36	GO:0016573	histone acetylation
0.35	GO:0048920	posterior lateral line neuromast primordium migration
0.34	GO:0051301	cell division
0.34	GO:1901642	nucleoside transmembrane transport
0.33	GO:0006413	translational initiation

0.37	GO:0004402	histone acetyltransferase activity
0.36	GO:0004871	signal transducer activity
0.34	GO:0005516	calmodulin binding
0.34	GO:0005337	nucleoside transmembrane transporter activity
0.33	GO:0003743	translation initiation factor activity

0.34	GO:1905360	GTPase complex
0.34	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.33	GO:0098797	plasma membrane protein complex
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.37

GO:0004402

tr|T1G223|T1G223_HELRO
Uncharacterized protein
Search

POLE3

0.81	DNA polymerase epsilon subunit 3

0.52	GO:0043966	histone H3 acetylation
0.43	GO:0034080	CENP-A containing nucleosome assembly
0.43	GO:0071480	cellular response to gamma radiation
0.42	GO:0042766	nucleosome mobilization
0.38	GO:0006974	cellular response to DNA damage stimulus
0.37	GO:0071897	DNA biosynthetic process
0.35	GO:0032201	telomere maintenance via semi-conservative replication
0.34	GO:0000082	G1/S transition of mitotic cell cycle
0.34	GO:0006270	DNA replication initiation
0.33	GO:0006779	porphyrin-containing compound biosynthetic process

0.74	GO:0046982	protein heterodimerization activity
0.41	GO:0004402	histone acetyltransferase activity
0.38	GO:0003887	DNA-directed DNA polymerase activity
0.35	GO:0003677	DNA binding
0.34	GO:0031491	nucleosome binding
0.34	GO:0070615	nucleosome-dependent ATPase activity
0.33	GO:0004655	porphobilinogen synthase activity
0.33	GO:0004386	helicase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding

0.59	GO:0005634	nucleus
0.51	GO:0031248	protein acetyltransferase complex
0.48	GO:0044427	chromosomal part
0.48	GO:0042575	DNA polymerase complex
0.47	GO:0031974	membrane-enclosed lumen
0.43	GO:0043234	protein complex
0.38	GO:1904949	ATPase complex

0.41	EC:2.3.1.48	GO:0004402
0.33	KEGG:R00036	GO:0004655

tr|T1G224|T1G224_HELRO
Uncharacterized protein
Search

0.10	5'-nucleotidase

0.75	GO:0009166	nucleotide catabolic process
0.46	GO:0046086	adenosine biosynthetic process
0.45	GO:0007159	leukocyte cell-cell adhesion
0.45	GO:0009169	purine ribonucleoside monophosphate catabolic process
0.44	GO:0050728	negative regulation of inflammatory response
0.43	GO:0016311	dephosphorylation
0.42	GO:0072523	purine-containing compound catabolic process
0.42	GO:0046033	AMP metabolic process
0.41	GO:0042737	drug catabolic process
0.41	GO:1901136	carbohydrate derivative catabolic process

0.61	GO:0016788	hydrolase activity, acting on ester bonds
0.54	GO:0046872	metal ion binding
0.53	GO:1901265	nucleoside phosphate binding
0.51	GO:0036094	small molecule binding
0.33	GO:0102485	dATP phosphohydrolase activity
0.33	GO:0102490	8-oxo-dGTP phosphohydrolase activity
0.33	GO:0102486	dCTP phosphohydrolase activity
0.33	GO:0102487	dUTP phosphohydrolase activity
0.33	GO:0102488	dTTP phosphohydrolase activity
0.33	GO:0102489	GTP phosphohydrolase activity

0.41	GO:0005654	nucleoplasm
0.40	GO:0005829	cytosol
0.37	GO:0005886	plasma membrane
0.36	GO:0031225	anchored component of membrane
0.35	GO:0070062	extracellular exosome
0.34	GO:0009986	cell surface
0.33	GO:0044456	synapse part
0.32	GO:0035145	exon-exon junction complex
0.32	GO:0071013	catalytic step 2 spliceosome
0.32	GO:0005911	cell-cell junction

0.61

GO:0016788

tr|T1G225|T1G225_HELRO
Uncharacterized protein
Search

0.55

GO:0055085

transmembrane transport

0.57	GO:0022857	transmembrane transporter activity
0.33	GO:0046872	metal ion binding

0.34	GO:0016323	basolateral plasma membrane
0.32	GO:0005887	integral component of plasma membrane

tr|T1G226|T1G226_HELRO
Uncharacterized protein
Search

0.70

LqfR-S

0.64	GO:0016192	vesicle-mediated transport
0.43	GO:0048477	oogenesis
0.43	GO:0008283	cell proliferation
0.38	GO:0098657	import into cell
0.38	GO:0036465	synaptic vesicle recycling
0.37	GO:0099643	signal release from synapse
0.37	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.37	GO:0048268	clathrin coat assembly
0.36	GO:0006836	neurotransmitter transport
0.36	GO:0045682	regulation of epidermis development

0.51	GO:0045296	cadherin binding
0.51	GO:0030276	clathrin binding
0.36	GO:0008289	lipid binding

0.68	GO:0005794	Golgi apparatus
0.47	GO:0005654	nucleoplasm
0.43	GO:0031410	cytoplasmic vesicle
0.40	GO:0031984	organelle subcompartment
0.37	GO:0045095	keratin filament
0.37	GO:0098793	presynapse
0.37	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|T1G227|T1G227_HELRO
Uncharacterized protein
Search

0.59	Glucose-dependent insulinotropic receptor

0.36	GO:0070647	protein modification by small protein conjugation or removal
0.34	GO:0042073	intraciliary transport
0.34	GO:0060271	cilium assembly
0.33	GO:0006508	proteolysis
0.33	GO:0006351	transcription, DNA-templated
0.33	GO:0006313	transposition, DNA-mediated
0.33	GO:0015074	DNA integration
0.33	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.32	GO:0016192	vesicle-mediated transport
0.32	GO:0006355	regulation of transcription, DNA-templated

0.35	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.34	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0015631	tubulin binding
0.33	GO:0043565	sequence-specific DNA binding
0.33	GO:0031683	G-protein beta/gamma-subunit complex binding
0.33	GO:0008270	zinc ion binding
0.33	GO:0000062	fatty-acyl-CoA binding
0.33	GO:0003700	DNA binding transcription factor activity
0.33	GO:0004636	phosphoribosyl-ATP diphosphatase activity
0.33	GO:0036094	small molecule binding

0.34	GO:0030992	intraciliary transport particle B
0.34	GO:0031514	motile cilium
0.33	GO:0030008	TRAPP complex
0.33	GO:0043231	intracellular membrane-bounded organelle
0.32	GO:0044444	cytoplasmic part
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.33	EC:3.6.1.31	GO:0004636
0.34	KEGG:R03876	GO:0004842

tr|T1G228|T1G228_HELRO
Uncharacterized protein
Search

0.42	GO:0006338	chromatin remodeling
0.40	GO:0060303	regulation of nucleosome density
0.38	GO:0032392	DNA geometric change

0.48	GO:0032559	adenyl ribonucleotide binding
0.47	GO:0008144	drug binding
0.47	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0043140	ATP-dependent 3'-5' DNA helicase activity

0.79	GO:0005869	dynactin complex
0.44	GO:0055120	striated muscle dense body
0.39	GO:0031011	Ino80 complex
0.36	GO:0005886	plasma membrane

tr|T1G229|T1G229_HELRO
Uncharacterized protein
Search

SSU72

0.88	RNA polymerase II subunit

0.72	GO:0006470	protein dephosphorylation
0.70	GO:0006397	mRNA processing
0.49	GO:0043631	RNA polyadenylation
0.48	GO:0031123	RNA 3'-end processing
0.47	GO:0006369	termination of RNA polymerase II transcription
0.47	GO:0006357	regulation of transcription by RNA polymerase II

0.72	GO:0004721	phosphoprotein phosphatase activity
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.44	GO:0031974	membrane-enclosed lumen
0.40	GO:0044446	intracellular organelle part
0.40	GO:0005829	cytosol
0.39	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

0.72

EC:3.1.3.16

GO:0004721

tr|T1G230|T1G230_HELRO
Serine/threonine-protein phosphatase
Search

0.39	Serine/threonine-protein phosphatase

0.71	GO:0006470	protein dephosphorylation
0.64	GO:0050906	detection of stimulus involved in sensory perception
0.36	GO:0045920	negative regulation of exocytosis
0.35	GO:0010801	negative regulation of peptidyl-threonine phosphorylation
0.35	GO:0043409	negative regulation of MAPK cascade
0.34	GO:0033365	protein localization to organelle
0.32	GO:0032259	methylation
0.32	GO:0055114	oxidation-reduction process
0.32	GO:0000055	ribosomal large subunit export from nucleus
0.32	GO:0060326	cell chemotaxis

0.72	GO:0004721	phosphoprotein phosphatase activity
0.65	GO:0005509	calcium ion binding
0.62	GO:0030145	manganese ion binding
0.54	GO:0005506	iron ion binding
0.38	GO:0051879	Hsp90 protein binding
0.36	GO:0031435	mitogen-activated protein kinase kinase kinase binding
0.36	GO:0030544	Hsp70 protein binding
0.32	GO:0008168	methyltransferase activity
0.32	GO:0016491	oxidoreductase activity
0.32	GO:0008009	chemokine activity

0.39	GO:0043025	neuronal cell body
0.35	GO:0072686	mitotic spindle
0.34	GO:0030425	dendrite
0.34	GO:0030424	axon
0.34	GO:0005929	cilium
0.33	GO:0043234	protein complex
0.32	GO:0005886	plasma membrane
0.32	GO:0005737	cytoplasm
0.32	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane

0.72

EC:3.1.3.16

GO:0004721

tr|T1G231|T1G231_HELRO
Uncharacterized protein
Search

NT5E

0.47	Trifunctional nucleotide phosphoesterase protein YfkN

0.75	GO:0009166	nucleotide catabolic process
0.51	GO:0046086	adenosine biosynthetic process
0.50	GO:0007159	leukocyte cell-cell adhesion
0.50	GO:0009169	purine ribonucleoside monophosphate catabolic process
0.48	GO:0050728	negative regulation of inflammatory response
0.46	GO:0072523	purine-containing compound catabolic process
0.45	GO:0046033	AMP metabolic process
0.45	GO:0016311	dephosphorylation
0.44	GO:0042737	drug catabolic process
0.44	GO:1901136	carbohydrate derivative catabolic process

0.60	GO:0016788	hydrolase activity, acting on ester bonds
0.53	GO:0046872	metal ion binding
0.53	GO:1901265	nucleoside phosphate binding
0.51	GO:0036094	small molecule binding
0.33	GO:0008768	UDP-sugar diphosphatase activity
0.32	GO:0003677	DNA binding

0.44	GO:0005654	nucleoplasm
0.43	GO:0005829	cytosol
0.39	GO:0005886	plasma membrane
0.37	GO:0031225	anchored component of membrane
0.35	GO:0070062	extracellular exosome
0.35	GO:0009986	cell surface
0.34	GO:0044456	synapse part
0.30	GO:0016021	integral component of membrane

0.60

GO:0016788

tr|T1G232|T1G232_HELRO
Uncharacterized protein
Search

0.10	adenylate cyclase type 9-like

0.76	GO:0009190	cyclic nucleotide biosynthetic process
0.63	GO:0035556	intracellular signal transduction
0.49	GO:0046058	cAMP metabolic process
0.47	GO:0071875	adrenergic receptor signaling pathway
0.46	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.45	GO:0009152	purine ribonucleotide biosynthetic process
0.45	GO:0046068	cGMP metabolic process
0.33	GO:0043547	positive regulation of GTPase activity
0.33	GO:0008610	lipid biosynthetic process
0.33	GO:0006281	DNA repair

0.75	GO:0016849	phosphorus-oxygen lyase activity
0.52	GO:1901265	nucleoside phosphate binding
0.50	GO:0009975	cyclase activity
0.50	GO:0036094	small molecule binding
0.34	GO:0046872	metal ion binding
0.34	GO:0005096	GTPase activator activity
0.33	GO:0097367	carbohydrate derivative binding
0.33	GO:0008144	drug binding
0.33	GO:0046982	protein heterodimerization activity
0.33	GO:0043168	anion binding

0.46	GO:0008074	guanylate cyclase complex, soluble
0.41	GO:0005887	integral component of plasma membrane
0.35	GO:0030425	dendrite
0.35	GO:0030424	axon

0.75

EC:4.6

GO:0016849

tr|T1G233|T1G233_HELRO
Uncharacterized protein
Search

0.48	Cytospin-A

0.49	GO:0051301	cell division
0.49	GO:0007049	cell cycle
0.45	GO:0097095	frontonasal suture morphogenesis
0.44	GO:0009966	regulation of signal transduction
0.43	GO:0043547	positive regulation of GTPase activity
0.42	GO:0060325	face morphogenesis
0.42	GO:0007026	negative regulation of microtubule depolymerization
0.41	GO:0030835	negative regulation of actin filament depolymerization
0.41	GO:0036211	protein modification process
0.40	GO:0007165	signal transduction

0.52	GO:0004386	helicase activity
0.45	GO:0005524	ATP binding
0.44	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.43	GO:0003676	nucleic acid binding
0.43	GO:0005096	GTPase activator activity
0.42	GO:0004674	protein serine/threonine kinase activity
0.40	GO:0008083	growth factor activity
0.40	GO:0001609	G-protein coupled adenosine receptor activity
0.39	GO:0004725	protein tyrosine phosphatase activity
0.38	GO:0002162	dystroglycan binding

0.56	GO:0005921	gap junction
0.54	GO:0005819	spindle
0.42	GO:0031941	filamentous actin
0.40	GO:0005815	microtubule organizing center
0.40	GO:0005737	cytoplasm
0.35	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.42

GO:0004674

tr|T1G234|T1G234_HELRO
Uncharacterized protein
Search

SELENOT

0.93	Selenoprotein T

0.55	GO:0035773	insulin secretion involved in cellular response to glucose stimulus
0.52	GO:0031016	pancreas development
0.46	GO:0045454	cell redox homeostasis
0.42	GO:0060124	positive regulation of growth hormone secretion
0.40	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.38	GO:0098869	cellular oxidant detoxification
0.35	GO:0055114	oxidation-reduction process
0.34	GO:0001514	selenocysteine incorporation
0.33	GO:0035556	intracellular signal transduction

0.40	GO:0004791	thioredoxin-disulfide reductase activity
0.35	GO:0008430	selenium binding
0.34	GO:0005201	extracellular matrix structural constituent
0.32	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.32	GO:0020037	heme binding
0.32	GO:0005506	iron ion binding

0.47	GO:0005783	endoplasmic reticulum
0.39	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.38	GO:0031984	organelle subcompartment
0.34	GO:0005604	basement membrane
0.34	GO:0005581	collagen trimer
0.30	GO:0016021	integral component of membrane

0.40	EC:1.8.1.9	GO:0004791
0.40	KEGG:R02016	GO:0004791

tr|T1G235|T1G235_HELRO
Uncharacterized protein
Search

tr|T1G236|T1G236_HELRO
Uncharacterized protein
Search

0.80	GO:0007219	Notch signaling pathway
0.70	GO:0030154	cell differentiation
0.68	GO:0007275	multicellular organism development
0.65	GO:0050793	regulation of developmental process
0.39	GO:0060325	face morphogenesis
0.38	GO:0042246	tissue regeneration
0.38	GO:0061448	connective tissue development
0.38	GO:0042593	glucose homeostasis
0.38	GO:0048646	anatomical structure formation involved in morphogenesis
0.36	GO:2001141	regulation of RNA biosynthetic process

0.70	GO:0005509	calcium ion binding
0.38	GO:0004872	receptor activity
0.36	GO:0008270	zinc ion binding
0.35	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.34	GO:0004713	protein tyrosine kinase activity
0.34	GO:0102568	phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
0.34	GO:0102567	phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
0.34	GO:0004623	phospholipase A2 activity
0.34	GO:0045296	cadherin binding
0.33	GO:0003682	chromatin binding

0.34	GO:0035003	subapical complex
0.34	GO:0043235	receptor complex
0.34	GO:0030139	endocytic vesicle
0.34	GO:0005770	late endosome
0.33	GO:0005912	adherens junction
0.33	GO:0005764	lysosome
0.33	GO:0015629	actin cytoskeleton
0.33	GO:0009986	cell surface
0.33	GO:0005634	nucleus
0.33	GO:0005829	cytosol

0.35

GO:0032440

tr|T1G237|T1G237_HELRO
Uncharacterized protein
Search

DLG1

0.70	Disks large like protein 1

0.76	GO:1903760	regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization
0.76	GO:1903764	regulation of potassium ion export across plasma membrane
0.75	GO:0051660	establishment of centrosome localization
0.75	GO:1903286	regulation of potassium ion import
0.75	GO:1903753	negative regulation of p38MAPK cascade
0.74	GO:0060022	hard palate development
0.74	GO:0001771	immunological synapse formation
0.74	GO:0030432	peristalsis
0.74	GO:0002369	T cell cytokine production
0.73	GO:0030953	astral microtubule organization

0.73	GO:0031434	mitogen-activated protein kinase kinase binding
0.73	GO:0097016	L27 domain binding
0.71	GO:0015459	potassium channel regulator activity
0.69	GO:0044325	ion channel binding
0.68	GO:0008022	protein C-terminus binding
0.68	GO:0019902	phosphatase binding
0.67	GO:0045296	cadherin binding
0.67	GO:0032947	protein complex scaffold activity
0.55	GO:0035255	ionotropic glutamate receptor binding
0.53	GO:0004385	guanylate kinase activity

0.75	GO:0043219	lateral loop
0.74	GO:0035748	myelin sheath abaxonal region
0.74	GO:0014069	postsynaptic density
0.73	GO:0033268	node of Ranvier
0.73	GO:0016323	basolateral plasma membrane
0.72	GO:0097025	MPP7-DLG1-LIN7 complex
0.72	GO:0005605	basal lamina
0.71	GO:0001772	immunological synapse
0.70	GO:0016328	lateral plasma membrane
0.69	GO:0031594	neuromuscular junction

0.53

GO:0004385

tr|T1G238|T1G238_HELRO
Uncharacterized protein
Search

0.48	Myosin essential light chain striated adductor

0.33	GO:0006468	protein phosphorylation
0.33	GO:0006950	response to stress

0.70	GO:0005509	calcium ion binding
0.34	GO:0017024	myosin I binding
0.33	GO:0004672	protein kinase activity
0.33	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.39	GO:0016459	myosin complex
0.32	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

tr|T1G239|T1G239_HELRO
Uncharacterized protein
Search

0.56	Stromal membrane-associated protein 1

0.76	GO:0043547	positive regulation of GTPase activity
0.33	GO:0016567	protein ubiquitination
0.33	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.32	GO:2001141	regulation of RNA biosynthetic process
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.76	GO:0005096	GTPase activator activity
0.52	GO:0046872	metal ion binding
0.34	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.34	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0003676	nucleic acid binding

0.34	EC:3.1.26.4	GO:0004523
0.34	KEGG:R03876	GO:0004842

tr|T1G240|T1G240_HELRO
Uncharacterized protein
Search

0.73	GO:0007219	Notch signaling pathway
0.62	GO:0007275	multicellular organism development
0.54	GO:0030154	cell differentiation
0.51	GO:0050793	regulation of developmental process
0.43	GO:0006355	regulation of transcription, DNA-templated
0.42	GO:0060561	apoptotic process involved in morphogenesis
0.41	GO:0009888	tissue development
0.41	GO:0045747	positive regulation of Notch signaling pathway
0.41	GO:0046629	gamma-delta T cell activation
0.40	GO:0003016	respiratory system process

0.70	GO:0005509	calcium ion binding
0.64	GO:0005112	Notch binding
0.47	GO:0004872	receptor activity
0.38	GO:0008083	growth factor activity
0.35	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.35	GO:0031490	chromatin DNA binding
0.35	GO:0001047	core promoter binding
0.35	GO:0004222	metalloendopeptidase activity
0.34	GO:0004857	enzyme inhibitor activity
0.34	GO:0046982	protein heterodimerization activity

0.37	GO:0005887	integral component of plasma membrane
0.37	GO:0043235	receptor complex
0.36	GO:0009986	cell surface
0.36	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex
0.35	GO:0016324	apical plasma membrane
0.35	GO:0005912	adherens junction
0.34	GO:0005634	nucleus
0.34	GO:0031410	cytoplasmic vesicle
0.34	GO:0005783	endoplasmic reticulum
0.34	GO:0070013	intracellular organelle lumen

0.35

GO:0004222

tr|T1G241|T1G241_HELRO
Uncharacterized protein
Search

0.67	OTXb-paired class homeobox protein (Fragment)

0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.53	GO:0007275	multicellular organism development
0.39	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.39	GO:0006366	transcription by RNA polymerase II
0.39	GO:0000904	cell morphogenesis involved in differentiation
0.39	GO:0051254	positive regulation of RNA metabolic process
0.39	GO:0010557	positive regulation of macromolecule biosynthetic process
0.39	GO:0031328	positive regulation of cellular biosynthetic process

0.63	GO:0043565	sequence-specific DNA binding
0.48	GO:0003700	DNA binding transcription factor activity
0.39	GO:0001012	RNA polymerase II regulatory region DNA binding
0.38	GO:0003690	double-stranded DNA binding
0.34	GO:0061630	ubiquitin protein ligase activity
0.34	GO:0042803	protein homodimerization activity
0.33	GO:0046982	protein heterodimerization activity
0.33	GO:0017171	serine hydrolase activity
0.32	GO:0070011	peptidase activity, acting on L-amino acid peptides

0.61	GO:0005634	nucleus
0.39	GO:0030426	growth cone
0.35	GO:0043234	protein complex

tr|T1G242|T1G242_HELRO
Uncharacterized protein
Search

0.47	Zinc finger, CDGSH-type

0.70

GO:0051537

2 iron, 2 sulfur cluster binding

0.55

GO:0043231

intracellular membrane-bounded organelle

tr|T1G243|T1G243_HELRO
Uncharacterized protein
Search

0.74	Ras-specific guanine nucleotide-releasing factor

0.77	GO:0007264	small GTPase mediated signal transduction
0.73	GO:0035023	regulation of Rho protein signal transduction
0.66	GO:0065009	regulation of molecular function
0.35	GO:1903013	response to differentiation-inducing factor 1
0.35	GO:0046956	positive phototaxis
0.35	GO:0043052	thermotaxis
0.34	GO:0051301	cell division
0.33	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.33	GO:0006508	proteolysis

0.75	GO:0005085	guanyl-nucleotide exchange factor activity
0.62	GO:0017048	Rho GTPase binding
0.34	GO:0004222	metalloendopeptidase activity
0.34	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.34	GO:0046982	protein heterodimerization activity
0.33	GO:0003676	nucleic acid binding
0.32	GO:0046872	metal ion binding
0.32	GO:0016740	transferase activity

0.45	GO:0005622	intracellular
0.33	GO:0005576	extracellular region
0.33	GO:0044815	DNA packaging complex
0.33	GO:0032993	protein-DNA complex
0.32	GO:0043228	non-membrane-bounded organelle
0.32	GO:0044422	organelle part
0.32	GO:0043227	membrane-bounded organelle
0.30	GO:0016020	membrane

0.34

GO:0004222

tr|T1G244|T1G244_HELRO
Uncharacterized protein
Search

TTLL9

0.84	probable tubulin polyglutamylase TTLL9

0.60

GO:0006464

cellular protein modification process

0.52	GO:0030554	adenyl nucleotide binding
0.51	GO:0097367	carbohydrate derivative binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0016874	ligase activity

0.40	GO:0005929	cilium
0.40	GO:0005874	microtubule
0.34	GO:0005737	cytoplasm

0.39

GO:0016874

tr|T1G245|T1G245_HELRO
Uncharacterized protein
Search

CPD

0.44	Carboxypeptidase D

0.61	GO:0006508	proteolysis
0.39	GO:0051604	protein maturation
0.37	GO:0006518	peptide metabolic process

0.78	GO:0004181	metallocarboxypeptidase activity
0.63	GO:0008270	zinc ion binding
0.54	GO:0004185	serine-type carboxypeptidase activity

0.40	GO:0005615	extracellular space
0.32	GO:0005622	intracellular
0.30	GO:0031224	intrinsic component of membrane

0.78

EC:3.4.17

GO:0004181

tr|T1G246|T1G246_HELRO
Uncharacterized protein
Search

TRAPPC13

0.95	Trafficking protein particle complex subunit 13

0.51

GO:0065009

regulation of molecular function

0.62

GO:0017112

Rab guanyl-nucleotide exchange factor activity

0.52

GO:0005829

cytosol

tr|T1G247|T1G247_HELRO
Uncharacterized protein
Search

UXS1

0.82	UDP-glucuronic acid decarboxylase

0.51	GO:0051262	protein tetramerization
0.42	GO:0033320	UDP-D-xylose biosynthetic process
0.39	GO:0030206	chondroitin sulfate biosynthetic process
0.39	GO:0015012	heparan sulfate proteoglycan biosynthetic process
0.39	GO:0051216	cartilage development
0.38	GO:0001503	ossification
0.38	GO:0030198	extracellular matrix organization

0.78	GO:0048040	UDP-glucuronate decarboxylase activity
0.51	GO:0070403	NAD+ binding
0.48	GO:0042803	protein homodimerization activity

0.40	GO:0005739	mitochondrion
0.39	GO:0032580	Golgi cisterna membrane
0.36	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.78	EC:4.1.1.35	GO:0048040
0.78	KEGG:R01384	GO:0048040

tr|T1G248|T1G248_HELRO
Uncharacterized protein
Search

IFT122

0.95	Intraflagellar transport protein 122

0.51	GO:0035721	intraciliary retrograde transport
0.50	GO:0061512	protein localization to cilium
0.50	GO:0045879	negative regulation of smoothened signaling pathway
0.49	GO:0060830	ciliary receptor clustering involved in smoothened signaling pathway
0.49	GO:0035720	intraciliary anterograde transport
0.49	GO:0060971	embryonic heart tube left/right pattern formation
0.49	GO:0007227	signal transduction downstream of smoothened
0.49	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning
0.49	GO:0010172	embryonic body morphogenesis
0.48	GO:0021513	spinal cord dorsal/ventral patterning

0.77	GO:0031514	motile cilium
0.50	GO:0030991	intraciliary transport particle A
0.47	GO:0097546	ciliary base
0.47	GO:0032391	photoreceptor connecting cilium
0.46	GO:0036064	ciliary basal body
0.42	GO:0005654	nucleoplasm
0.41	GO:0005829	cytosol
0.30	GO:0016020	membrane

tr|T1G249|T1G249_HELRO
Uncharacterized protein
Search

0.10	NO-insensitive guanylyl cyclase III (Fragment)

0.81	GO:0006182	cGMP biosynthetic process
0.63	GO:0035556	intracellular signal transduction
0.60	GO:0006468	protein phosphorylation
0.44	GO:0045792	negative regulation of cell size
0.42	GO:0007030	Golgi organization
0.42	GO:0045931	positive regulation of mitotic cell cycle
0.41	GO:0008284	positive regulation of cell proliferation
0.35	GO:0006506	GPI anchor biosynthetic process
0.34	GO:0007020	microtubule nucleation
0.34	GO:0055093	response to hyperoxia

0.81	GO:0004383	guanylate cyclase activity
0.61	GO:0004672	protein kinase activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0004016	adenylate cyclase activity
0.36	GO:0020037	heme binding
0.35	GO:0051377	mannose-ethanolamine phosphotransferase activity
0.35	GO:0004872	receptor activity
0.34	GO:0051287	NAD binding

0.45	GO:0005622	intracellular
0.37	GO:0043234	protein complex
0.37	GO:0005886	plasma membrane
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0009986	cell surface
0.34	GO:0098552	side of membrane
0.33	GO:0044422	organelle part
0.33	GO:0043227	membrane-bounded organelle
0.32	GO:0043228	non-membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.81

GO:0004383

tr|T1G250|T1G250_HELRO
Protein-serine/threonine kinase
Search

0.69	G protein-coupled receptor kinase

0.63	GO:0006468	protein phosphorylation
0.61	GO:0007165	signal transduction
0.49	GO:0031623	receptor internalization
0.42	GO:0003315	heart rudiment formation
0.41	GO:0042429	serotonin catabolic process
0.41	GO:0051239	regulation of multicellular organismal process
0.41	GO:0060160	negative regulation of dopamine receptor signaling pathway
0.40	GO:0040010	positive regulation of growth rate
0.40	GO:1902074	response to salt
0.40	GO:0048520	positive regulation of behavior

0.85	GO:0004703	G-protein coupled receptor kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0047696	beta-adrenergic receptor kinase activity
0.35	GO:0031748	D1 dopamine receptor binding
0.34	GO:0016868	intramolecular transferase activity, phosphotransferases
0.33	GO:0000287	magnesium ion binding

0.35	GO:0044292	dendrite terminus
0.35	GO:0097225	sperm midpiece
0.35	GO:0043198	dendritic shaft
0.34	GO:0043197	dendritic spine
0.34	GO:0005829	cytosol
0.34	GO:0030018	Z disc
0.34	GO:0030424	axon
0.34	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0005634	nucleus
0.32	GO:0005886	plasma membrane

0.85

EC:2.7.11.16

GO:0004703

tr|T1G251|T1G251_HELRO
Uncharacterized protein
Search

0.63	Guanylate cyclase soluble subunit beta-2

0.80	GO:0006182	cGMP biosynthetic process
0.63	GO:0035556	intracellular signal transduction
0.57	GO:0006468	protein phosphorylation
0.34	GO:0060038	cardiac muscle cell proliferation
0.34	GO:0007601	visual perception
0.33	GO:0006508	proteolysis
0.33	GO:0008654	phospholipid biosynthetic process
0.32	GO:0006355	regulation of transcription, DNA-templated

0.80	GO:0004383	guanylate cyclase activity
0.57	GO:0004672	protein kinase activity
0.52	GO:1901265	nucleoside phosphate binding
0.51	GO:0036094	small molecule binding
0.49	GO:0097367	carbohydrate derivative binding
0.49	GO:0008144	drug binding
0.48	GO:0043168	anion binding
0.43	GO:0020037	heme binding
0.42	GO:0004016	adenylate cyclase activity
0.34	GO:0005515	protein binding

0.45	GO:0005622	intracellular
0.37	GO:0043234	protein complex
0.37	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.80

GO:0004383

tr|T1G252|T1G252_HELRO
Uncharacterized protein
Search

0.66	Glycogenin glucosyltransferase

0.38	GO:0005978	glycogen biosynthetic process
0.32	GO:0006508	proteolysis

0.65	GO:0016757	transferase activity, transferring glycosyl groups
0.33	GO:0004185	serine-type carboxypeptidase activity

0.37	GO:0005829	cytosol
0.30	GO:0044425	membrane part

0.65

GO:0016757

tr|T1G253|T1G253_HELRO
DNA ligase
Search

LIG4

0.40	DNA ligase

0.80	GO:0051103	DNA ligation involved in DNA repair
0.67	GO:0071897	DNA biosynthetic process
0.65	GO:0006310	DNA recombination
0.63	GO:0006260	DNA replication
0.55	GO:0006297	nucleotide-excision repair, DNA gap filling
0.55	GO:0097680	double-strand break repair via classical nonhomologous end joining
0.54	GO:0002328	pro-B cell differentiation
0.53	GO:0016445	somatic diversification of immunoglobulins
0.53	GO:0000012	single strand break repair
0.53	GO:0002568	somatic diversification of T cell receptor genes

0.78	GO:0003910	DNA ligase (ATP) activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.55	GO:0003677	DNA binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0008022	protein C-terminus binding
0.43	GO:0004672	protein kinase activity
0.34	GO:0046872	metal ion binding
0.33	GO:0003777	microtubule motor activity
0.33	GO:0008017	microtubule binding

0.56	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex
0.56	GO:0032807	DNA ligase IV complex
0.50	GO:0036464	cytoplasmic ribonucleoprotein granule
0.48	GO:0000793	condensed chromosome
0.46	GO:0005654	nucleoplasm
0.34	GO:0000784	nuclear chromosome, telomeric region
0.30	GO:0016020	membrane

0.78

EC:6.5.1.1

GO:0003910

tr|T1G254|T1G254_HELRO
Uncharacterized protein
Search

RIMBP2

0.45	RIMS binding protein 2

0.79

GO:0010923

negative regulation of phosphatase activity

0.48

GO:0030156

benzodiazepine receptor binding

0.46	GO:0045202	synapse
0.46	GO:0030054	cell junction
0.39	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

tr|T1G255|T1G255_HELRO
Uncharacterized protein
Search

LOC102367966

0.96	Pleckstrin y domain-containing family A member 3

0.71

GO:0120009

intermembrane lipid transfer

0.71	GO:0120013	intermembrane lipid transfer activity
0.53	GO:0008289	lipid binding

0.44	GO:0005737	cytoplasm
0.42	GO:0005581	collagen trimer
0.30	GO:0044425	membrane part

tr|T1G256|T1G256_HELRO
Uncharacterized protein
Search

0.58	Ubiquitin specific peptidase 54

0.76

GO:0016579

protein deubiquitination

0.77	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.34	GO:0005515	protein binding

0.77

GO:0036459

tr|T1G257|T1G257_HELRO
Uncharacterized protein
Search

tr|T1G258|T1G258_HELRO
Uncharacterized protein
Search

0.60	Putative syntaxin-binding protein 2 (Fragment)

0.39	GO:0046856	phosphatidylinositol dephosphorylation
0.38	GO:0016579	protein deubiquitination
0.38	GO:0006270	DNA replication initiation
0.34	GO:0005975	carbohydrate metabolic process

0.40	GO:0034597	phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity
0.39	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.36	GO:0046983	protein dimerization activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0003677	DNA binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0016853	isomerase activity
0.33	GO:0016740	transferase activity

0.30

GO:0016020

membrane

0.40

EC:3.1.3.66

GO:0034597

tr|T1G259|T1G259_HELRO
Uncharacterized protein
Search

0.69	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta

0.44	GO:0040024	dauer larval development
0.44	GO:0051220	cytoplasmic sequestering of protein
0.44	GO:0042308	negative regulation of protein import into nucleus
0.37	GO:0030590	first cell cycle pseudocleavage
0.37	GO:0010070	zygote asymmetric cell division
0.36	GO:0035046	pronuclear migration
0.36	GO:0009949	polarity specification of anterior/posterior axis
0.36	GO:0045167	asymmetric protein localization involved in cell fate determination
0.36	GO:0006911	phagocytosis, engulfment
0.36	GO:0010286	heat acclimation

0.77	GO:0019904	protein domain specific binding
0.40	GO:0008134	transcription factor binding
0.33	GO:0004222	metalloendopeptidase activity
0.33	GO:0004497	monooxygenase activity
0.32	GO:0046872	metal ion binding

0.38	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm
0.33	GO:0071944	cell periphery
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0004222

tr|T1G260|T1G260_HELRO
Uncharacterized protein
Search

0.83	Zinc finger protein ZIC 5

0.55	GO:0007417	central nervous system development
0.53	GO:0060322	head development
0.53	GO:0048513	animal organ development
0.50	GO:0061351	neural precursor cell proliferation
0.46	GO:0048598	embryonic morphogenesis
0.43	GO:0021915	neural tube development
0.42	GO:0072175	epithelial tube formation
0.41	GO:0030154	cell differentiation
0.41	GO:0060070	canonical Wnt signaling pathway
0.40	GO:0008589	regulation of smoothened signaling pathway

0.51	GO:0003676	nucleic acid binding
0.39	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.34	GO:0046872	metal ion binding

0.40	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm

tr|T1G261|T1G261_HELRO
Uncharacterized protein
Search

0.47	GO:1902001	fatty acid transmembrane transport
0.44	GO:0045893	positive regulation of transcription, DNA-templated

0.44	GO:0003723	RNA binding
0.41	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.38	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding

0.45	GO:0005779	integral component of peroxisomal membrane
0.40	GO:0005634	nucleus

tr|T1G262|T1G262_HELRO
Uncharacterized protein
Search

FGD6

0.70	Putative rho/rac guanine nucleotide exchange factor/faciogenital dysplasia protein 3 (Fragment)

0.78	GO:0035023	regulation of Rho protein signal transduction
0.66	GO:0065009	regulation of molecular function

0.78	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.54	GO:0046872	metal ion binding

tr|T1G263|T1G263_HELRO
Uncharacterized protein
Search

SPG7

0.88	Spastic paraplegia 7 (pure and complicated autosomal recessive)

0.61	GO:0006508	proteolysis
0.52	GO:1902686	mitochondrial outer membrane permeabilization involved in programmed cell death
0.51	GO:0008089	anterograde axonal transport
0.35	GO:0051013	microtubule severing
0.35	GO:0006851	mitochondrial calcium ion transmembrane transport
0.34	GO:0043043	peptide biosynthetic process
0.34	GO:0044267	cellular protein metabolic process
0.34	GO:0030155	regulation of cell adhesion
0.34	GO:0007399	nervous system development
0.33	GO:0007155	cell adhesion

0.70	GO:0004222	metalloendopeptidase activity
0.60	GO:0008270	zinc ion binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0008568	microtubule-severing ATPase activity
0.35	GO:0003735	structural constituent of ribosome
0.35	GO:0051082	unfolded protein binding
0.34	GO:0004176	ATP-dependent peptidase activity
0.32	GO:0003676	nucleic acid binding

0.53	GO:0005757	mitochondrial permeability transition pore complex
0.52	GO:0005745	m-AAA complex
0.50	GO:1904115	axon cytoplasm
0.34	GO:0005840	ribosome

0.70

GO:0004222

tr|T1G264|T1G264_HELRO
Uncharacterized protein
Search

DDX51

0.55	DEAD (Asp-Glu-Ala-Asp) box polypeptide 51

0.46	GO:0010501	RNA secondary structure unwinding
0.36	GO:0006364	rRNA processing
0.35	GO:0030522	intracellular receptor signaling pathway
0.35	GO:0043401	steroid hormone mediated signaling pathway
0.33	GO:0048254	snoRNA localization
0.33	GO:0006351	transcription, DNA-templated
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:0010468	regulation of gene expression
0.33	GO:0034471	ncRNA 5'-end processing

0.66	GO:0004386	helicase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0003676	nucleic acid binding
0.45	GO:0008186	RNA-dependent ATPase activity
0.40	GO:0140098	catalytic activity, acting on RNA
0.36	GO:0004887	thyroid hormone receptor activity
0.35	GO:0003707	steroid hormone receptor activity
0.34	GO:0008270	zinc ion binding

0.44	GO:0005730	nucleolus
0.36	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1G265|T1G265_HELRO
Uncharacterized protein
Search

UBE2A

0.50	Ubiquitin-conjugating enzyme

0.50	GO:0016574	histone ubiquitination
0.49	GO:0000209	protein polyubiquitination
0.46	GO:0051865	protein autoubiquitination
0.45	GO:0009411	response to UV
0.45	GO:0060135	maternal process involved in female pregnancy
0.44	GO:0008284	positive regulation of cell proliferation
0.44	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.43	GO:0006281	DNA repair
0.43	GO:0001701	in utero embryonic development

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0061631	ubiquitin conjugating enzyme activity
0.49	GO:0031625	ubiquitin protein ligase binding
0.43	GO:0061630	ubiquitin protein ligase activity
0.38	GO:0016874	ligase activity
0.34	GO:0043130	ubiquitin binding
0.33	GO:0003697	single-stranded DNA binding

0.53	GO:0031371	ubiquitin conjugating enzyme complex
0.49	GO:0000792	heterochromatin
0.47	GO:0000151	ubiquitin ligase complex
0.46	GO:0000790	nuclear chromatin
0.46	GO:0001741	XY body
0.36	GO:0005737	cytoplasm
0.33	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.38

GO:0016874

tr|T1G266|T1G266_HELRO
Oxysterol-binding protein
Search

0.50	Oxysterol-binding protein (Fragment)

0.74

GO:0006869

lipid transport

0.32

GO:0016787

hydrolase activity

0.30

GO:0044425

membrane part

0.32

GO:0016787

tr|T1G267|T1G267_HELRO
Uncharacterized protein
Search

0.52	Potassium voltage-gated channel protein Shaw

0.73	GO:0071805	potassium ion transmembrane transport
0.73	GO:0034765	regulation of ion transmembrane transport
0.73	GO:0051260	protein homooligomerization
0.34	GO:0006379	mRNA cleavage
0.33	GO:0006351	transcription, DNA-templated

0.78	GO:0005249	voltage-gated potassium channel activity
0.36	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.33	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.33	GO:0046872	metal ion binding
0.32	GO:0003676	nucleic acid binding

0.78	GO:0008076	voltage-gated potassium channel complex
0.35	GO:0032809	neuronal cell body membrane
0.35	GO:0032590	dendrite membrane
0.35	GO:0030673	axolemma

0.36

GO:0004114

tr|T1G268|T1G268_HELRO
Uncharacterized protein
Search

ABCD4

0.95	ATP-binding cassette sub-family D member 4

0.55	GO:0055085	transmembrane transport
0.54	GO:1990823	response to leukemia inhibitory factor
0.51	GO:0071345	cellular response to cytokine stimulus
0.48	GO:0009235	cobalamin metabolic process

0.66	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.50	GO:0042579	microbody
0.48	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0005765	lysosomal membrane
0.33	GO:0043190	ATP-binding cassette (ABC) transporter complex

tr|T1G269|T1G269_HELRO
Uncharacterized protein
Search

ERF1

0.69	Eukaryotic peptide chain release factor subunit

0.74	GO:0006415	translational termination
0.42	GO:0008213	protein alkylation
0.40	GO:0043414	macromolecule methylation
0.40	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.39	GO:0007420	brain development
0.34	GO:0007224	smoothened signaling pathway
0.34	GO:0006449	regulation of translational termination
0.33	GO:0016032	viral process

0.75	GO:0008079	translation termination factor activity
0.47	GO:1990825	sequence-specific mRNA binding
0.34	GO:0043022	ribosome binding
0.33	GO:0005515	protein binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.49	GO:0005737	cytoplasm
0.34	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|T1G270|T1G270_HELRO
Uncharacterized protein
Search

0.51	GO:0006468	protein phosphorylation
0.41	GO:0010376	stomatal complex formation
0.41	GO:1905034	regulation of antifungal innate immune response
0.41	GO:0010375	stomatal complex patterning
0.40	GO:0010090	trichome morphogenesis
0.40	GO:0071215	cellular response to abscisic acid stimulus
0.39	GO:0008356	asymmetric cell division
0.39	GO:0050832	defense response to fungus
0.36	GO:0002376	immune system process
0.36	GO:0007165	signal transduction

0.51	GO:0004672	protein kinase activity
0.45	GO:0030554	adenyl nucleotide binding
0.45	GO:0097367	carbohydrate derivative binding
0.45	GO:0008144	drug binding
0.45	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0033612	receptor serine/threonine kinase binding
0.38	GO:0042277	peptide binding
0.36	GO:0005509	calcium ion binding
0.36	GO:0004180	carboxypeptidase activity
0.35	GO:0004930	G-protein coupled receptor activity

0.36	GO:0031012	extracellular matrix
0.36	GO:0009505	plant-type cell wall
0.36	GO:0055044	symplast
0.36	GO:0005911	cell-cell junction
0.35	GO:0005886	plasma membrane
0.34	GO:0005615	extracellular space
0.33	GO:0005829	cytosol
0.33	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.35	EC:3.1.3.16	GO:0004721
0.34	KEGG:R03876	GO:0004842

tr|T1G271|T1G271_HELRO
Uncharacterized protein
Search

0.69	GO:0006357	regulation of transcription by RNA polymerase II
0.49	GO:0048518	positive regulation of biological process
0.49	GO:0006366	transcription by RNA polymerase II
0.46	GO:0002070	epithelial cell maturation
0.46	GO:0007028	cytoplasm organization
0.45	GO:0007431	salivary gland development
0.45	GO:0008340	determination of adult lifespan
0.45	GO:0009653	anatomical structure morphogenesis
0.43	GO:0040008	regulation of growth
0.42	GO:0001568	blood vessel development

0.60	GO:0003700	DNA binding transcription factor activity
0.48	GO:0043565	sequence-specific DNA binding
0.45	GO:0001012	RNA polymerase II regulatory region DNA binding
0.44	GO:0003690	double-stranded DNA binding
0.40	GO:0008022	protein C-terminus binding
0.38	GO:0008134	transcription factor binding
0.35	GO:0004386	helicase activity
0.34	GO:0008270	zinc ion binding
0.34	GO:0003746	translation elongation factor activity
0.33	GO:0005524	ATP binding

0.47	GO:0005634	nucleus
0.44	GO:0043233	organelle lumen
0.41	GO:0044446	intracellular organelle part
0.41	GO:0005829	cytosol
0.38	GO:0005739	mitochondrion
0.38	GO:0043232	intracellular non-membrane-bounded organelle
0.35	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

tr|T1G272|T1G272_HELRO
Uncharacterized protein
Search

0.51	Thrombospondin 1

0.81	GO:0016525	negative regulation of angiogenesis
0.81	GO:0030198	extracellular matrix organization
0.74	GO:0006954	inflammatory response
0.72	GO:0007155	cell adhesion
0.56	GO:0002605	negative regulation of dendritic cell antigen processing and presentation
0.56	GO:0010754	negative regulation of cGMP-mediated signaling
0.56	GO:0010751	negative regulation of nitric oxide mediated signal transduction
0.55	GO:2001027	negative regulation of endothelial cell chemotaxis
0.55	GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport
0.55	GO:0010757	negative regulation of plasminogen activation

0.80	GO:0008201	heparin binding
0.78	GO:0050840	extracellular matrix binding
0.70	GO:0005509	calcium ion binding
0.56	GO:0070052	collagen V binding
0.56	GO:0070051	fibrinogen binding
0.54	GO:0030169	low-density lipoprotein particle binding
0.54	GO:0001968	fibronectin binding
0.53	GO:0017134	fibroblast growth factor binding
0.53	GO:0001786	phosphatidylserine binding
0.52	GO:0005178	integrin binding

0.74	GO:0031012	extracellular matrix
0.69	GO:0005615	extracellular space
0.55	GO:0031091	platelet alpha granule
0.51	GO:0009897	external side of plasma membrane
0.42	GO:0016529	sarcoplasmic reticulum
0.42	GO:0043234	protein complex
0.38	GO:1903561	extracellular vesicle
0.35	GO:0034774	secretory granule lumen
0.35	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0016021	integral component of membrane

tr|T1G273|T1G273_HELRO
Uncharacterized protein
Search

MAPKAPK5

0.75	Mitogen-activated protein kinase-activated protein kinase 5

0.63	GO:0006468	protein phosphorylation
0.50	GO:0018209	peptidyl-serine modification
0.44	GO:0031328	positive regulation of cellular biosynthetic process
0.44	GO:0010557	positive regulation of macromolecule biosynthetic process
0.44	GO:0044351	macropinocytosis
0.44	GO:0007569	cell aging
0.44	GO:0051173	positive regulation of nitrogen compound metabolic process
0.44	GO:0035556	intracellular signal transduction
0.44	GO:0070935	3'-UTR-mediated mRNA stabilization
0.43	GO:0051246	regulation of protein metabolic process

0.64	GO:0004672	protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.45	GO:0019901	protein kinase binding
0.41	GO:0005516	calmodulin binding
0.41	GO:0031625	ubiquitin protein ligase binding
0.40	GO:0042803	protein homodimerization activity
0.39	GO:0002039	p53 binding

0.44	GO:0005654	nucleoplasm
0.41	GO:0005813	centrosome
0.41	GO:0000781	chromosome, telomeric region
0.39	GO:0005794	Golgi apparatus
0.36	GO:0005829	cytosol
0.33	GO:0005641	nuclear envelope lumen
0.33	GO:0031588	nucleotide-activated protein kinase complex
0.32	GO:0000324	fungal-type vacuole
0.32	GO:0072686	mitotic spindle
0.30	GO:0016020	membrane

tr|T1G274|T1G274_HELRO
Uncharacterized protein
Search

0.78	sterile alpha and TIR motif-containing protein 1

0.61	GO:0007165	signal transduction
0.36	GO:1901214	regulation of neuron death

0.35	GO:0030425	dendrite
0.30	GO:0044425	membrane part

tr|T1G275|T1G275_HELRO
Uncharacterized protein
Search

PDE12

0.94	Putative glucose-repressible alcohol dehydrogenase transcriptional effector ccr4

0.86	GO:0000958	mitochondrial mRNA catabolic process
0.85	GO:0090324	negative regulation of oxidative phosphorylation
0.85	GO:0044528	regulation of mitochondrial mRNA stability
0.85	GO:0035457	cellular response to interferon-alpha
0.83	GO:0045070	positive regulation of viral genome replication
0.81	GO:0071346	cellular response to interferon-gamma
0.80	GO:0071359	cellular response to dsRNA
0.77	GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
0.74	GO:0060548	negative regulation of cell death
0.72	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic

0.77	GO:0000175	3'-5'-exoribonuclease activity
0.39	GO:0004519	endonuclease activity
0.38	GO:0046872	metal ion binding
0.37	GO:0004017	adenylate kinase activity
0.34	GO:0016887	ATPase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.71	GO:0005759	mitochondrial matrix
0.35	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.77

EC:3.1.13

GO:0000175

tr|T1G276|T1G276_HELRO
Uncharacterized protein
Search

ASCC1

0.93	Activating signal cointegrator 1 complex subunit 1

0.40	GO:1903506	regulation of nucleic acid-templated transcription
0.40	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.39	GO:0010468	regulation of gene expression
0.37	GO:0061055	myotome development
0.37	GO:0001966	thigmotaxis
0.36	GO:0007528	neuromuscular junction development
0.35	GO:0007409	axonogenesis
0.34	GO:0006307	DNA dealkylation involved in DNA repair
0.33	GO:0006351	transcription, DNA-templated
0.33	GO:0007165	signal transduction

0.58	GO:0003723	RNA binding
0.34	GO:0005509	calcium ion binding
0.33	GO:0016874	ligase activity
0.33	GO:0005515	protein binding

0.50	GO:0031594	neuromuscular junction
0.46	GO:0005667	transcription factor complex
0.41	GO:0005634	nucleus
0.34	GO:0005578	proteinaceous extracellular matrix
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.33

GO:0016874

tr|T1G277|T1G277_HELRO
Uncharacterized protein
Search

PIWIL1

0.90	Piwi like RNA-mediated gene silencing 1

0.79	GO:0031047	gene silencing by RNA
0.68	GO:0007286	spermatid development
0.54	GO:0034587	piRNA metabolic process
0.52	GO:0010529	negative regulation of transposition
0.50	GO:0043486	histone exchange
0.49	GO:0006997	nucleus organization
0.47	GO:0006323	DNA packaging
0.45	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.39	GO:0009653	anatomical structure morphogenesis
0.38	GO:0051321	meiotic cell cycle

0.74	GO:0034584	piRNA binding
0.48	GO:0003727	single-stranded RNA binding
0.48	GO:0019901	protein kinase binding
0.47	GO:0003729	mRNA binding
0.45	GO:0004521	endoribonuclease activity
0.34	GO:0003743	translation initiation factor activity
0.34	GO:0046872	metal ion binding

0.52	GO:0033391	chromatoid body
0.51	GO:0097433	dense body
0.51	GO:0005845	mRNA cap binding complex
0.49	GO:0005844	polysome
0.44	GO:0043186	P granule
0.42	GO:0005634	nucleus
0.33	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

tr|T1G278|T1G278_HELRO
Uncharacterized protein
Search

0.78	GO:0008543	fibroblast growth factor receptor signaling pathway
0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.73	GO:0008284	positive regulation of cell proliferation
0.47	GO:2000830	positive regulation of parathyroid hormone secretion
0.46	GO:0021769	orbitofrontal cortex development
0.46	GO:0048378	regulation of lateral mesodermal cell fate specification
0.46	GO:0010518	positive regulation of phospholipase activity
0.46	GO:0021847	ventricular zone neuroblast division
0.46	GO:1903465	positive regulation of mitotic cell cycle DNA replication
0.46	GO:1904849	positive regulation of cell chemotaxis to fibroblast growth factor

0.81	GO:0005007	fibroblast growth factor-activated receptor activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0017134	fibroblast growth factor binding
0.46	GO:0090722	receptor-receptor interaction
0.42	GO:0042802	identical protein binding
0.41	GO:1901681	sulfur compound binding
0.40	GO:0046983	protein dimerization activity

0.43	GO:0043235	receptor complex
0.41	GO:0005730	nucleolus
0.38	GO:0005886	plasma membrane
0.36	GO:0031410	cytoplasmic vesicle
0.34	GO:0030424	axon
0.34	GO:0012505	endomembrane system
0.34	GO:0005829	cytosol
0.34	GO:0009986	cell surface
0.34	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0005764	lysosome

0.32

EC:3.6.1.3

GO:0016887

tr|T1G279|T1G279_HELRO
Receptor protein serine/threonine kinase
Search

0.47	Receptor protein serine/threonine kinase

0.80	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
0.66	GO:0023014	signal transduction by protein phosphorylation
0.51	GO:0071363	cellular response to growth factor stimulus
0.50	GO:0071559	response to transforming growth factor beta
0.49	GO:0071495	cellular response to endogenous stimulus
0.46	GO:0060541	respiratory system development
0.46	GO:0072001	renal system development
0.46	GO:0035239	tube morphogenesis
0.46	GO:0007389	pattern specification process
0.46	GO:0048598	embryonic morphogenesis

0.79	GO:0004702	signal transducer, downstream of receptor, with serine/threonine kinase activity
0.79	GO:0004675	transmembrane receptor protein serine/threonine kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.48	GO:0046872	metal ion binding
0.46	GO:0048185	activin binding
0.45	GO:0019838	growth factor binding
0.41	GO:0019955	cytokine binding

0.49	GO:0043235	receptor complex
0.42	GO:0035230	cytoneme
0.41	GO:0005771	multivesicular body
0.39	GO:0005769	early endosome
0.39	GO:1902554	serine/threonine protein kinase complex
0.38	GO:0098793	presynapse
0.37	GO:0005887	integral component of plasma membrane
0.36	GO:0043234	protein complex
0.34	GO:0045178	basal part of cell
0.33	GO:0005829	cytosol

0.79	EC:2.7.11	GO:0004702
0.33	KEGG:R01364	GO:0004334

tr|T1G280|T1G280_HELRO
Phospholipid-transporting ATPase
Search

0.50	Phospholipid-transporting ATPase

0.80	GO:0045332	phospholipid translocation
0.39	GO:0007030	Golgi organization
0.37	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.37	GO:0032880	regulation of protein localization
0.36	GO:0006833	water transport
0.33	GO:0055085	transmembrane transport

0.81	GO:0004012	phospholipid-translocating ATPase activity
0.64	GO:0000287	magnesium ion binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0022803	passive transmembrane transporter activity

0.39	GO:0071683	sensory dendrite
0.37	GO:0005929	cilium
0.37	GO:0012505	endomembrane system
0.35	GO:0097223	sperm part
0.35	GO:0043227	membrane-bounded organelle
0.34	GO:0044444	cytoplasmic part
0.34	GO:0043229	intracellular organelle
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.81

EC:3.6.3.1

GO:0004012

tr|T1G281|T1G281_HELRO
Protein phosphatase methylesterase 1
Search

PPME1

0.73	Protein phosphatase methylesterase 1

0.84	GO:0006482	protein demethylation
0.46	GO:0043666	regulation of phosphoprotein phosphatase activity
0.35	GO:0000086	G2/M transition of mitotic cell cycle
0.35	GO:0002028	regulation of sodium ion transport
0.35	GO:0035308	negative regulation of protein dephosphorylation
0.35	GO:0010923	negative regulation of phosphatase activity

0.79	GO:0051723	protein methylesterase activity
0.57	GO:0051721	protein phosphatase 2A binding
0.53	GO:0045296	cadherin binding
0.47	GO:0019888	protein phosphatase regulator activity
0.37	GO:0019901	protein kinase binding
0.35	GO:0019212	phosphatase inhibitor activity
0.33	GO:0016740	transferase activity

0.34	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0016740

tr|T1G282|T1G282_HELRO
Uncharacterized protein
Search

NT5E

0.48	5'-nucleotidase ecto

0.75	GO:0009166	nucleotide catabolic process
0.51	GO:0046086	adenosine biosynthetic process
0.49	GO:0007159	leukocyte cell-cell adhesion
0.49	GO:0009169	purine ribonucleoside monophosphate catabolic process
0.48	GO:0050728	negative regulation of inflammatory response
0.45	GO:0072523	purine-containing compound catabolic process
0.45	GO:0046033	AMP metabolic process
0.44	GO:0016311	dephosphorylation
0.43	GO:0042737	drug catabolic process
0.43	GO:1901136	carbohydrate derivative catabolic process

0.60	GO:0016788	hydrolase activity, acting on ester bonds
0.53	GO:0046872	metal ion binding
0.52	GO:1901265	nucleoside phosphate binding
0.51	GO:0036094	small molecule binding
0.33	GO:0008768	UDP-sugar diphosphatase activity
0.32	GO:0003677	DNA binding

0.43	GO:0005654	nucleoplasm
0.43	GO:0005829	cytosol
0.39	GO:0005886	plasma membrane
0.37	GO:0031225	anchored component of membrane
0.35	GO:0070062	extracellular exosome
0.35	GO:0009986	cell surface
0.33	GO:0044456	synapse part
0.30	GO:0016021	integral component of membrane

0.60

GO:0016788

tr|T1G283|T1G283_HELRO
Uncharacterized protein
Search

tr|T1G284|T1G284_HELRO
Uncharacterized protein
Search

0.56	calsyntenin-1

0.75	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.47	GO:0051965	positive regulation of synapse assembly
0.47	GO:0050806	positive regulation of synaptic transmission
0.40	GO:0001558	regulation of cell growth
0.39	GO:1990126	retrograde transport, endosome to plasma membrane
0.38	GO:0050770	regulation of axonogenesis
0.38	GO:0008361	regulation of cell size
0.38	GO:0048638	regulation of developmental growth
0.35	GO:0051609	inhibition of neurotransmitter uptake
0.34	GO:0009405	pathogenesis

0.70	GO:0005509	calcium ion binding
0.39	GO:0042988	X11-like protein binding
0.38	GO:0001540	amyloid-beta binding
0.38	GO:0019894	kinesin binding
0.34	GO:0090729	toxin activity
0.34	GO:0008013	beta-catenin binding
0.34	GO:0004222	metalloendopeptidase activity
0.33	GO:0003735	structural constituent of ribosome
0.33	GO:0001883	purine nucleoside binding
0.33	GO:0032561	guanyl ribonucleotide binding

0.47	GO:0014069	postsynaptic density
0.45	GO:0045211	postsynaptic membrane
0.44	GO:0009986	cell surface
0.36	GO:0005615	extracellular space
0.36	GO:0000139	Golgi membrane
0.35	GO:0005789	endoplasmic reticulum membrane
0.34	GO:1903561	extracellular vesicle
0.33	GO:0030054	cell junction
0.33	GO:0005840	ribosome
0.33	GO:0042995	cell projection

0.34

GO:0004222

tr|T1G285|T1G285_HELRO
Uncharacterized protein
Search

0.43	Hypoxanthine phosphoribosyltransferase

0.77	GO:0032264	IMP salvage
0.75	GO:0006166	purine ribonucleoside salvage

0.79	GO:0004422	hypoxanthine phosphoribosyltransferase activity
0.78	GO:0052657	guanine phosphoribosyltransferase activity
0.52	GO:0046872	metal ion binding
0.51	GO:1901265	nucleoside phosphate binding
0.50	GO:0036094	small molecule binding

0.48	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.79	EC:2.4.2.8	GO:0004422
0.79	KEGG:R01132	GO:0004422

tr|T1G286|T1G286_HELRO
Uncharacterized protein
Search

tr|T1G287|T1G287_HELRO
Uncharacterized protein
Search

ECA

0.88	Transmembrane emp24 domain-containing protein eca

0.49	GO:0009953	dorsal/ventral pattern formation
0.40	GO:0048042	regulation of post-mating oviposition
0.37	GO:0048193	Golgi vesicle transport
0.37	GO:0061355	Wnt protein secretion
0.36	GO:0034389	lipid particle organization
0.36	GO:0035220	wing disc development
0.36	GO:0007030	Golgi organization
0.35	GO:0006432	phenylalanyl-tRNA aminoacylation
0.34	GO:0046907	intracellular transport

0.35	GO:0004826	phenylalanine-tRNA ligase activity
0.34	GO:0000049	tRNA binding
0.34	GO:0005215	transporter activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003677	DNA binding

0.68	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0071565	nBAF complex
0.34	GO:0071564	npBAF complex
0.34	GO:0016514	SWI/SNF complex
0.30	GO:0016021	integral component of membrane

0.35

EC:6.1.1.20

GO:0004826

tr|T1G288|T1G288_HELRO
Cytochrome c oxidase subunit
Search

0.73	Cytochrome c oxidase polypeptide VIb

0.51	GO:0033617	mitochondrial respiratory chain complex IV assembly
0.43	GO:1902600	hydrogen ion transmembrane transport
0.43	GO:0022900	electron transport chain
0.34	GO:0021762	substantia nigra development
0.33	GO:0034968	histone lysine methylation
0.33	GO:2001141	regulation of RNA biosynthetic process
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression
0.33	GO:0006119	oxidative phosphorylation
0.33	GO:0009060	aerobic respiration

0.44	GO:0015002	heme-copper terminal oxidase activity
0.44	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.43	GO:0015078	hydrogen ion transmembrane transporter activity
0.43	GO:0009055	electron transfer activity
0.33	GO:0043565	sequence-specific DNA binding
0.33	GO:0018024	histone-lysine N-methyltransferase activity
0.33	GO:0003700	DNA binding transcription factor activity
0.32	GO:0008270	zinc ion binding

0.61	GO:0005739	mitochondrion
0.50	GO:0031970	organelle envelope lumen
0.48	GO:0045277	respiratory chain complex IV
0.45	GO:0019866	organelle inner membrane
0.34	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.44

EC:1.9.3

GO:0016676

tr|T1G289|T1G289_HELRO
Uncharacterized protein
Search

0.55	GO:0055085	transmembrane transport
0.49	GO:0042908	xenobiotic transport
0.45	GO:0015893	drug transport
0.36	GO:0071702	organic substance transport
0.36	GO:0032940	secretion by cell
0.36	GO:0042886	amide transport
0.35	GO:0045184	establishment of protein localization
0.34	GO:0043207	response to external biotic stimulus
0.34	GO:0006811	ion transport
0.34	GO:0051704	multi-organism process

0.66	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0042910	xenobiotic transmembrane transporter activity
0.46	GO:0015238	drug transmembrane transporter activity
0.36	GO:0015197	peptide transporter activity
0.35	GO:0008281	sulfonylurea receptor activity
0.35	GO:0008514	organic anion transmembrane transporter activity
0.35	GO:0032440	2-alkenal reductase [NAD(P)] activity

0.40	GO:0000325	plant-type vacuole
0.39	GO:0005887	integral component of plasma membrane
0.39	GO:0005774	vacuolar membrane
0.37	GO:0030256	type I protein secretion system complex
0.33	GO:0005634	nucleus

0.35

GO:0032440

tr|T1G290|T1G290_HELRO
Uncharacterized protein
Search

TLK2

0.92	Tousled like protein kinase

0.62	GO:0006468	protein phosphorylation
0.50	GO:0071480	cellular response to gamma radiation
0.50	GO:0001672	regulation of chromatin assembly or disassembly
0.49	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process
0.47	GO:0018209	peptidyl-serine modification
0.44	GO:0007059	chromosome segregation
0.42	GO:0006974	cellular response to DNA damage stimulus
0.41	GO:0035556	intracellular signal transduction
0.34	GO:0010507	negative regulation of autophagy
0.34	GO:0016569	covalent chromatin modification

0.62	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005515	protein binding

0.50	GO:0005634	nucleus
0.47	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0005882	intermediate filament
0.30	GO:0016020	membrane

tr|T1G291|T1G291_HELRO
Uncharacterized protein
Search

0.95	Winged helix transcription factor delta (Fragment)

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:1902257	negative regulation of apoptotic process involved in outflow tract morphogenesis
0.56	GO:0014032	neural crest cell development
0.55	GO:0072010	glomerular epithelium development
0.54	GO:0048341	paraxial mesoderm formation
0.54	GO:0003018	vascular process in circulatory system
0.54	GO:0001756	somitogenesis
0.54	GO:0001944	vasculature development

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.53	GO:1990841	promoter-specific chromatin binding
0.49	GO:0031490	chromatin DNA binding
0.49	GO:0044212	transcription regulatory region DNA binding
0.45	GO:0042802	identical protein binding
0.43	GO:0001223	transcription coactivator binding
0.41	GO:0008301	DNA binding, bending
0.41	GO:0003713	transcription coactivator activity
0.38	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.45	GO:0070013	intracellular organelle lumen
0.41	GO:0044446	intracellular organelle part
0.38	GO:0005829	cytosol
0.38	GO:0005694	chromosome
0.30	GO:0016020	membrane

tr|T1G292|T1G292_HELRO
Uncharacterized protein
Search

PIGS

0.75	Phosphatidylinositol glycan anchor biosynthesis class S

0.83	GO:0016255	attachment of GPI anchor to protein
0.33	GO:0015074	DNA integration
0.32	GO:0055114	oxidation-reduction process

0.54	GO:0003923	GPI-anchor transamidase activity
0.33	GO:0016706	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
0.33	GO:0031418	L-ascorbic acid binding
0.33	GO:0005515	protein binding
0.32	GO:0005506	iron ion binding
0.32	GO:0003676	nucleic acid binding

0.81

GO:0042765

GPI-anchor transamidase complex

0.54

GO:0003923

tr|T1G293|T1G293_HELRO
Uncharacterized protein
Search

0.74	TNF receptor-associated factor 1 (Fragment)

0.74	GO:0042981	regulation of apoptotic process
0.58	GO:1902533	positive regulation of intracellular signal transduction
0.56	GO:0007165	signal transduction
0.54	GO:1901222	regulation of NIK/NF-kappaB signaling
0.53	GO:0046328	regulation of JNK cascade
0.53	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling
0.51	GO:0032147	activation of protein kinase activity
0.51	GO:0071902	positive regulation of protein serine/threonine kinase activity
0.44	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.43	GO:0090073	positive regulation of protein homodimerization activity

0.78	GO:0005164	tumor necrosis factor receptor binding
0.61	GO:0008270	zinc ion binding
0.50	GO:0031996	thioesterase binding
0.47	GO:0031625	ubiquitin protein ligase binding
0.45	GO:0042802	identical protein binding
0.43	GO:0050699	WW domain binding
0.41	GO:0019901	protein kinase binding

0.37	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm

tr|T1G294|T1G294_HELRO
Uncharacterized protein
Search

0.83	GO:0071526	semaphorin-plexin signaling pathway
0.54	GO:1902667	regulation of axon guidance
0.51	GO:0008045	motor neuron axon guidance
0.51	GO:0021644	vagus nerve morphogenesis
0.51	GO:0021784	postganglionic parasympathetic fiber development
0.50	GO:0021615	glossopharyngeal nerve morphogenesis
0.50	GO:0061643	chemorepulsion of axon
0.50	GO:0050923	regulation of negative chemotaxis
0.50	GO:0021637	trigeminal nerve structural organization
0.50	GO:0021960	anterior commissure morphogenesis

0.84	GO:0017154	semaphorin receptor activity
0.44	GO:0010853	cyclase activator activity
0.44	GO:0071889	14-3-3 protein binding
0.44	GO:0030249	guanylate cyclase regulator activity
0.43	GO:0008201	heparin binding
0.41	GO:0005096	GTPase activator activity

0.36	GO:0005887	integral component of plasma membrane
0.34	GO:0002116	semaphorin receptor complex
0.34	GO:0005622	intracellular

tr|T1G295|T1G295_HELRO
Uncharacterized protein
Search

0.47	GO:0007482	haltere development
0.47	GO:0045433	male courtship behavior, veined wing generated song production
0.46	GO:0007526	larval somatic muscle development
0.46	GO:0002168	instar larval development
0.45	GO:0007591	molting cycle, chitin-based cuticle
0.37	GO:1903506	regulation of nucleic acid-templated transcription
0.37	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.37	GO:0010468	regulation of gene expression
0.34	GO:0034968	histone lysine methylation
0.34	GO:0071805	potassium ion transmembrane transport

0.54	GO:0046872	metal ion binding
0.39	GO:0003700	DNA binding transcription factor activity
0.34	GO:0018024	histone-lysine N-methyltransferase activity
0.34	GO:0005249	voltage-gated potassium channel activity

0.39	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.34

EC:2.1.1.43

GO:0018024

tr|T1G296|T1G296_HELRO
Uncharacterized protein
Search

GET4

0.93	Golgi to ER traffic protein 4

0.80	GO:0045048	protein insertion into ER membrane
0.74	GO:1904378	maintenance of unfolded protein involved in ERAD pathway
0.70	GO:0051220	cytoplasmic sequestering of protein

0.62	GO:0051087	chaperone binding
0.39	GO:0016798	hydrolase activity, acting on glycosyl bonds
0.35	GO:0003723	RNA binding

0.85	GO:0071818	BAT3 complex
0.60	GO:0005730	nucleolus
0.57	GO:0005654	nucleoplasm
0.39	GO:0106094	nuclear membrane microtubule tethering complex
0.39	GO:0034992	microtubule organizing center attachment site
0.39	GO:0031229	intrinsic component of nuclear inner membrane
0.38	GO:0031301	integral component of organelle membrane

0.39

EC:3.2

GO:0016798

tr|T1G297|T1G297_HELRO
Uncharacterized protein
Search

tr|T1G298|T1G298_HELRO
Uncharacterized protein
Search

0.52	Collagen alpha-1(IV) chain preproprotein (Fragment)

0.51	GO:0052548	regulation of endopeptidase activity
0.51	GO:0010466	negative regulation of peptidase activity
0.45	GO:0035987	endodermal cell differentiation
0.42	GO:0030198	extracellular matrix organization
0.42	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.40	GO:0007528	neuromuscular junction development
0.39	GO:0071230	cellular response to amino acid stimulus
0.39	GO:0061304	retinal blood vessel morphogenesis
0.39	GO:0007399	nervous system development
0.39	GO:0001569	branching involved in blood vessel morphogenesis

0.70	GO:0005201	extracellular matrix structural constituent
0.52	GO:0004867	serine-type endopeptidase inhibitor activity
0.42	GO:0042802	identical protein binding
0.39	GO:0048407	platelet-derived growth factor binding
0.36	GO:0042302	structural constituent of cuticle
0.35	GO:0005509	calcium ion binding
0.34	GO:0097367	carbohydrate derivative binding
0.34	GO:0005102	receptor binding
0.34	GO:0008144	drug binding
0.34	GO:0030554	adenyl nucleotide binding

0.71	GO:0005581	collagen trimer
0.64	GO:0005604	basement membrane
0.43	GO:0098644	complex of collagen trimers
0.39	GO:0099081	supramolecular polymer
0.39	GO:0005615	extracellular space
0.35	GO:0005694	chromosome
0.35	GO:0031594	neuromuscular junction
0.34	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane
0.34	GO:0005788	endoplasmic reticulum lumen
0.34	GO:0030056	hemidesmosome

0.34

GO:0004715

tr|T1G299|T1G299_HELRO
Uncharacterized protein
Search

tr|T1G2A0|T1G2A0_HELRO
Uncharacterized protein
Search

0.50	GO:0035989	tendon development
0.50	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound
0.49	GO:0035987	endodermal cell differentiation
0.49	GO:0001502	cartilage condensation
0.49	GO:0030198	extracellular matrix organization
0.49	GO:0002063	chondrocyte development
0.48	GO:0055010	ventricular cardiac muscle tissue morphogenesis
0.47	GO:0042472	inner ear morphogenesis
0.47	GO:0006029	proteoglycan metabolic process
0.47	GO:0048704	embryonic skeletal system morphogenesis

0.72	GO:0005201	extracellular matrix structural constituent
0.45	GO:0042302	structural constituent of cuticle
0.40	GO:0048407	platelet-derived growth factor binding
0.37	GO:0005178	integrin binding
0.35	GO:0097493	structural molecule activity conferring elasticity
0.34	GO:0002020	protease binding
0.34	GO:0050840	extracellular matrix binding
0.34	GO:0008061	chitin binding
0.34	GO:0004867	serine-type endopeptidase inhibitor activity
0.34	GO:0030674	protein binding, bridging

0.69	GO:0005581	collagen trimer
0.60	GO:0044420	extracellular matrix component
0.57	GO:0005578	proteinaceous extracellular matrix
0.47	GO:0099081	supramolecular polymer
0.46	GO:0005615	extracellular space
0.36	GO:0005788	endoplasmic reticulum lumen
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|T1G2A1|T1G2A1_HELRO
Uncharacterized protein
Search

0.49	GO:0016525	negative regulation of angiogenesis
0.48	GO:0030198	extracellular matrix organization
0.45	GO:0007155	cell adhesion

0.48	GO:0008201	heparin binding
0.44	GO:0005509	calcium ion binding

0.68	GO:0005654	nucleoplasm
0.46	GO:0031012	extracellular matrix

tr|T1G2A2|T1G2A2_HELRO
Uncharacterized protein
Search

TIMM10

0.79	Translocase of inner mitochondrial membrane 10

0.84	GO:0045039	protein import into mitochondrial inner membrane
0.50	GO:0072321	chaperone-mediated protein transport
0.40	GO:0040014	regulation of multicellular organism growth
0.38	GO:0000003	reproduction
0.34	GO:0007605	sensory perception of sound

0.70	GO:0008565	protein transporter activity
0.54	GO:0046872	metal ion binding
0.45	GO:0051087	chaperone binding
0.45	GO:0042803	protein homodimerization activity

0.85	GO:0042719	mitochondrial intermembrane space protein transporter complex
0.84	GO:0042721	mitochondrial inner membrane protein insertion complex
0.34	GO:0005744	mitochondrial inner membrane presequence translocase complex
0.30	GO:0031224	intrinsic component of membrane

tr|T1G2A3|T1G2A3_HELRO
Uncharacterized protein
Search

tr|T1G2A4|T1G2A4_HELRO
Uncharacterized protein
Search

0.61	GO:0006508	proteolysis
0.44	GO:0006898	receptor-mediated endocytosis
0.37	GO:0006958	complement activation, classical pathway
0.36	GO:0009166	nucleotide catabolic process
0.35	GO:0006030	chitin metabolic process
0.34	GO:0007190	activation of adenylate cyclase activity
0.34	GO:0007340	acrosome reaction
0.34	GO:0007596	blood coagulation
0.33	GO:0051604	protein maturation

0.69	GO:0004252	serine-type endopeptidase activity
0.46	GO:0005044	scavenger receptor activity
0.36	GO:0005509	calcium ion binding
0.35	GO:0008061	chitin binding
0.34	GO:0042806	fucose binding
0.34	GO:0005537	mannose binding
0.34	GO:0016788	hydrolase activity, acting on ester bonds
0.33	GO:0004040	amidase activity
0.33	GO:0004181	metallocarboxypeptidase activity
0.33	GO:1901265	nucleoside phosphate binding

0.42	GO:0005576	extracellular region
0.41	GO:0031226	intrinsic component of plasma membrane
0.37	GO:0001669	acrosomal vesicle
0.36	GO:0031225	anchored component of membrane
0.36	GO:0019897	extrinsic component of plasma membrane
0.33	GO:0044437	vacuolar part
0.33	GO:0044433	cytoplasmic vesicle part
0.32	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.69

GO:0004252

tr|T1G2A5|T1G2A5_HELRO
Uncharacterized protein
Search

FUT8

0.89	Fucosyltransferase 8

0.80	GO:0036071	N-glycan fucosylation
0.80	GO:0033578	protein glycosylation in Golgi
0.52	GO:0018279	protein N-linked glycosylation via asparagine
0.51	GO:0046368	GDP-L-fucose metabolic process
0.50	GO:0007585	respiratory gaseous exchange
0.49	GO:1900407	regulation of cellular response to oxidative stress
0.49	GO:0006491	N-glycan processing
0.49	GO:0007179	transforming growth factor beta receptor signaling pathway
0.48	GO:0043112	receptor metabolic process
0.47	GO:0007229	integrin-mediated signaling pathway

0.81	GO:0046921	alpha-(1->6)-fucosyltransferase activity
0.73	GO:0140103	catalytic activity, acting on a glycoprotein
0.39	GO:0017124	SH3 domain binding
0.33	GO:0030983	mismatched DNA binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.72	GO:0032580	Golgi cisterna membrane
0.45	GO:0005829	cytosol
0.35	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.81

GO:0046921

tr|T1G2A6|T1G2A6_HELRO
Eukaryotic translation initiation factor 6
Search

EIF6

0.69	Eukaryotic translation initiation factor 6

0.79	GO:0042256	mature ribosome assembly
0.74	GO:0042273	ribosomal large subunit biogenesis
0.72	GO:0006413	translational initiation
0.61	GO:0000054	ribosomal subunit export from nucleus
0.43	GO:1902626	assembly of large subunit precursor of preribosome
0.42	GO:0000460	maturation of 5.8S rRNA
0.37	GO:0045652	regulation of megakaryocyte differentiation
0.36	GO:0006110	regulation of glycolytic process
0.36	GO:0042304	regulation of fatty acid biosynthetic process
0.36	GO:0032868	response to insulin

0.76	GO:0043023	ribosomal large subunit binding
0.74	GO:0043022	ribosome binding
0.72	GO:0003743	translation initiation factor activity
0.35	GO:0005537	mannose binding
0.33	GO:0004930	G-protein coupled receptor activity

0.71	GO:0005730	nucleolus
0.48	GO:0005737	cytoplasm
0.42	GO:0030687	preribosome, large subunit precursor
0.37	GO:0005638	lamin filament
0.34	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

tr|T1G2A7|T1G2A7_HELRO
Uncharacterized protein
Search

tr|T1G2A8|T1G2A8_HELRO
Uncharacterized protein
Search

EPHX4

0.39	Pimeloyl-ACP methyl ester carboxylesterase

0.37	GO:0044255	cellular lipid metabolic process
0.36	GO:0009166	nucleotide catabolic process

0.46	GO:0016787	hydrolase activity
0.35	GO:0016746	transferase activity, transferring acyl groups
0.33	GO:0046872	metal ion binding
0.33	GO:0000166	nucleotide binding

0.30

GO:0031224

intrinsic component of membrane

0.46

GO:0016787

tr|T1G2A9|T1G2A9_HELRO
Uncharacterized protein
Search

0.36	GO:0048208	COPII vesicle coating
0.36	GO:0009443	pyridoxal 5'-phosphate salvage
0.35	GO:0018193	peptidyl-amino acid modification
0.35	GO:0006475	internal protein amino acid acetylation
0.35	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.35	GO:0016570	histone modification
0.34	GO:0006357	regulation of transcription by RNA polymerase II
0.34	GO:0015031	protein transport
0.34	GO:0006457	protein folding
0.33	GO:0016310	phosphorylation

0.37	GO:0003712	transcription cofactor activity
0.36	GO:0008478	pyridoxal kinase activity
0.35	GO:0004402	histone acetyltransferase activity
0.35	GO:0046872	metal ion binding
0.35	GO:0031683	G-protein beta/gamma-subunit complex binding
0.34	GO:0003697	single-stranded DNA binding
0.34	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.34	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0003700	DNA binding transcription factor activity

0.35	GO:0000139	Golgi membrane
0.35	GO:0005783	endoplasmic reticulum
0.35	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.36

EC:2.7.1.35

GO:0008478

tr|T1G2B0|T1G2B0_HELRO
Uncharacterized protein
Search

NDUFA2

0.41	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit

0.55	GO:0032981	mitochondrial respiratory chain complex I assembly
0.52	GO:0055114	oxidation-reduction process

0.47

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.62	GO:0070469	respiratory chain
0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.56	GO:0030964	NADH dehydrogenase complex
0.53	GO:0098798	mitochondrial protein complex
0.50	GO:1990204	oxidoreductase complex
0.46	GO:0098796	membrane protein complex

0.47

GO:0008137

tr|T1G2B1|T1G2B1_HELRO
Uncharacterized protein
Search

0.48	GO:0001952	regulation of cell-matrix adhesion
0.48	GO:0030239	myofibril assembly
0.38	GO:0006468	protein phosphorylation
0.35	GO:0001878	response to yeast
0.33	GO:0051496	positive regulation of stress fiber assembly
0.33	GO:0007165	signal transduction
0.32	GO:0007399	nervous system development

0.54	GO:0046872	metal ion binding
0.50	GO:0051371	muscle alpha-actinin binding
0.45	GO:0003779	actin binding
0.38	GO:0004672	protein kinase activity
0.36	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005201	extracellular matrix structural constituent
0.32	GO:0004871	signal transducer activity

0.50	GO:0005927	muscle tendon junction
0.50	GO:0005915	zonula adherens
0.49	GO:0045178	basal part of cell
0.48	GO:0097517	contractile actin filament bundle
0.48	GO:0042641	actomyosin
0.48	GO:0030018	Z disc
0.47	GO:0016323	basolateral plasma membrane
0.47	GO:0005925	focal adhesion
0.47	GO:0045177	apical part of cell
0.47	GO:0031252	cell leading edge

tr|T1G2B2|T1G2B2_HELRO
Uncharacterized protein
Search

0.10	Accumulation-associated protein (Fragment)

0.50	GO:0030198	extracellular matrix organization
0.47	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.46	GO:0071230	cellular response to amino acid stimulus
0.42	GO:0006508	proteolysis
0.40	GO:0010811	positive regulation of cell-substrate adhesion
0.39	GO:0006614	SRP-dependent cotranslational protein targeting to membrane

0.57	GO:0005201	extracellular matrix structural constituent
0.43	GO:0005509	calcium ion binding
0.42	GO:0008233	peptidase activity
0.40	GO:0003774	motor activity
0.40	GO:0050840	extracellular matrix binding
0.39	GO:0003779	actin binding
0.37	GO:0003924	GTPase activity
0.37	GO:0032550	purine ribonucleoside binding
0.37	GO:0032561	guanyl ribonucleotide binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.60	GO:0005581	collagen trimer
0.57	GO:0005604	basement membrane
0.48	GO:0098645	collagen network
0.41	GO:0016459	myosin complex
0.38	GO:0005615	extracellular space
0.37	GO:0031226	intrinsic component of plasma membrane
0.34	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.42

GO:0008233

tr|T1G2B3|T1G2B3_HELRO
Uncharacterized protein
Search

0.53	Lysine-specific demethylase 5A

0.53	GO:0032259	methylation
0.47	GO:0034721	histone H3-K4 demethylation, trimethyl-H3-K4-specific
0.43	GO:0051090	regulation of DNA binding transcription factor activity
0.43	GO:1901726	negative regulation of histone deacetylase activity
0.42	GO:0045893	positive regulation of transcription, DNA-templated
0.41	GO:0032922	circadian regulation of gene expression
0.39	GO:0000122	negative regulation of transcription by RNA polymerase II
0.33	GO:0036098	male germ-line stem cell population maintenance
0.33	GO:0043970	histone H3-K9 acetylation
0.33	GO:0030717	karyosome formation

0.54	GO:0003677	DNA binding
0.53	GO:0046872	metal ion binding
0.53	GO:0008168	methyltransferase activity
0.47	GO:0034647	histone demethylase activity (H3-trimethyl-K4 specific)
0.47	GO:0034648	histone demethylase activity (H3-dimethyl-K4 specific)
0.45	GO:0140034	methylation-dependent protein binding
0.43	GO:0042393	histone binding
0.42	GO:0001067	regulatory region nucleic acid binding
0.39	GO:0003713	transcription coactivator activity
0.39	GO:0003682	chromatin binding

0.61	GO:0005634	nucleus
0.45	GO:0150005	enzyme activator complex
0.44	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.38	GO:0032993	protein-DNA complex
0.38	GO:0044446	intracellular organelle part
0.32	GO:0005694	chromosome
0.32	GO:0031974	membrane-enclosed lumen
0.30	GO:0016020	membrane

0.53

GO:0008168

tr|T1G2B4|T1G2B4_HELRO
Uncharacterized protein
Search

0.48	GO:0009190	cyclic nucleotide biosynthetic process
0.46	GO:0007165	signal transduction
0.45	GO:0045087	innate immune response
0.44	GO:0016310	phosphorylation
0.43	GO:0046058	cAMP metabolic process
0.42	GO:0051014	actin filament severing
0.41	GO:0036211	protein modification process
0.40	GO:0009152	purine ribonucleotide biosynthetic process
0.40	GO:0007010	cytoskeleton organization
0.40	GO:0044267	cellular protein metabolic process

0.47	GO:0016849	phosphorus-oxygen lyase activity
0.46	GO:0016301	kinase activity
0.43	GO:0009975	cyclase activity
0.42	GO:0042802	identical protein binding
0.41	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.40	GO:0140096	catalytic activity, acting on a protein
0.40	GO:0051015	actin filament binding
0.40	GO:0030554	adenyl nucleotide binding
0.40	GO:0000287	magnesium ion binding
0.39	GO:0097367	carbohydrate derivative binding

0.36	GO:0005622	intracellular
0.35	GO:0031982	vesicle
0.35	GO:0012505	endomembrane system
0.34	GO:0097610	cell surface furrow
0.34	GO:0009897	external side of plasma membrane
0.34	GO:0032155	cell division site part
0.33	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.47

EC:4.6

GO:0016849

tr|T1G2B5|T1G2B5_HELRO
Uncharacterized protein
Search

BCS1L

0.76	BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone

0.84	GO:0017062	respiratory chain complex III assembly
0.84	GO:0097033	mitochondrial respiratory chain complex III biogenesis
0.81	GO:0033108	mitochondrial respiratory chain complex assembly
0.54	GO:0097031	mitochondrial respiratory chain complex I biogenesis
0.54	GO:0010257	NADH dehydrogenase complex assembly
0.53	GO:0097034	mitochondrial respiratory chain complex IV biogenesis
0.53	GO:0008535	respiratory chain complex IV assembly
0.33	GO:0055114	oxidation-reduction process

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.34	GO:0020037	heme binding
0.34	GO:0005506	iron ion binding
0.33	GO:0005515	protein binding

0.61	GO:0005739	mitochondrion
0.36	GO:0019866	organelle inner membrane
0.34	GO:0045275	respiratory chain complex III
0.30	GO:0016021	integral component of membrane

0.34

GO:0016705

tr|T1G2B6|T1G2B6_HELRO
Uncharacterized protein
Search

0.47	Myosin essential light chain, striated adductor muscle

0.33

GO:0006950

response to stress

0.70

GO:0005509

calcium ion binding

0.39	GO:0016459	myosin complex
0.30	GO:0031224	intrinsic component of membrane

tr|T1G2B7|T1G2B7_HELRO
Uncharacterized protein
Search

0.73	GO:0035335	peptidyl-tyrosine dephosphorylation
0.37	GO:0000188	inactivation of MAPK activity
0.36	GO:0016310	phosphorylation
0.35	GO:0001522	pseudouridine synthesis

0.79	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.73	GO:0004725	protein tyrosine phosphatase activity
0.40	GO:0051015	actin filament binding
0.37	GO:0033549	MAP kinase phosphatase activity
0.36	GO:0016301	kinase activity
0.35	GO:0009982	pseudouridine synthase activity
0.33	GO:0003723	RNA binding

0.34

GO:0005887

integral component of plasma membrane

0.79

EC:3.1.3

GO:0008138

tr|T1G2B8|T1G2B8_HELRO
Uncharacterized protein
Search

tr|T1G2B9|T1G2B9_HELRO
Uncharacterized protein
Search

0.73	LYR motif-containing protein 4

0.66	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity
0.58	GO:0006289	nucleotide-excision repair
0.52	GO:0016226	iron-sulfur cluster assembly
0.48	GO:0006508	proteolysis

0.67	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity
0.54	GO:0031071	cysteine desulfurase activity
0.53	GO:0004252	serine-type endopeptidase activity

0.64	GO:0005675	holo TFIIH complex
0.60	GO:1990221	L-cysteine desulfurase complex
0.55	GO:0031314	extrinsic component of mitochondrial inner membrane
0.52	GO:0005759	mitochondrial matrix

0.54

EC:2.8.1.7

GO:0031071

tr|T1G2C0|T1G2C0_HELRO
Uncharacterized protein
Search

0.31	Aminoacyl-tRNA hydrolase

0.74	GO:0006415	translational termination
0.45	GO:0072344	rescue of stalled ribosome
0.43	GO:0032543	mitochondrial translation

0.75	GO:0003747	translation release factor activity
0.44	GO:0004045	aminoacyl-tRNA hydrolase activity

0.44	GO:0005762	mitochondrial large ribosomal subunit
0.33	GO:0031966	mitochondrial membrane
0.33	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

0.44

EC:3.1.1.29

GO:0004045

tr|T1G2C1|T1G2C1_HELRO
Uncharacterized protein
Search

0.42	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.41	GO:0035987	endodermal cell differentiation
0.40	GO:0016525	negative regulation of angiogenesis
0.40	GO:0071560	cellular response to transforming growth factor beta stimulus
0.38	GO:0010466	negative regulation of peptidase activity
0.37	GO:0052548	regulation of endopeptidase activity
0.37	GO:0061327	anterior Malpighian tubule development
0.37	GO:0007443	Malpighian tubule morphogenesis
0.36	GO:0007519	skeletal muscle tissue development
0.36	GO:0006351	transcription, DNA-templated

0.67	GO:0005201	extracellular matrix structural constituent
0.38	GO:0030414	peptidase inhibitor activity
0.37	GO:0061135	endopeptidase regulator activity
0.37	GO:0005509	calcium ion binding
0.35	GO:0042302	structural constituent of cuticle
0.34	GO:0003677	DNA binding
0.34	GO:0008201	heparin binding
0.34	GO:0030246	carbohydrate binding
0.32	GO:0005515	protein binding

0.63	GO:0005581	collagen trimer
0.55	GO:0044420	extracellular matrix component
0.53	GO:0005578	proteinaceous extracellular matrix
0.40	GO:0099081	supramolecular polymer
0.40	GO:0005615	extracellular space
0.35	GO:0005938	cell cortex
0.33	GO:1903561	extracellular vesicle
0.33	GO:0009986	cell surface
0.30	GO:0016020	membrane

tr|T1G2C2|T1G2C2_HELRO
Uncharacterized protein
Search

0.63	Potassium voltage-gated channel subfamily KQT member

0.73	GO:0071805	potassium ion transmembrane transport
0.49	GO:0060048	cardiac muscle contraction
0.49	GO:0001700	embryonic development via the syncytial blastoderm
0.48	GO:0002027	regulation of heart rate

0.78

GO:0005249

voltage-gated potassium channel activity

0.78

GO:0008076

voltage-gated potassium channel complex

tr|T1G2C3|T1G2C3_HELRO
Uncharacterized protein
Search

0.45	GO:0052548	regulation of endopeptidase activity
0.45	GO:0010466	negative regulation of peptidase activity
0.43	GO:0030198	extracellular matrix organization
0.42	GO:0007275	multicellular organism development
0.41	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.40	GO:0009653	anatomical structure morphogenesis
0.40	GO:0071230	cellular response to amino acid stimulus
0.39	GO:0007528	neuromuscular junction development
0.38	GO:0009888	tissue development
0.38	GO:0060322	head development

0.65	GO:0005201	extracellular matrix structural constituent
0.49	GO:0042302	structural constituent of cuticle
0.45	GO:0004867	serine-type endopeptidase inhibitor activity
0.41	GO:0048407	platelet-derived growth factor binding
0.37	GO:0002020	protease binding
0.37	GO:0005178	integrin binding
0.36	GO:0046332	SMAD binding
0.36	GO:0030674	protein binding, bridging
0.35	GO:0042802	identical protein binding
0.35	GO:0008201	heparin binding

0.67	GO:0005581	collagen trimer
0.60	GO:0044420	extracellular matrix component
0.58	GO:0005578	proteinaceous extracellular matrix
0.41	GO:0005615	extracellular space
0.41	GO:0099081	supramolecular polymer
0.40	GO:0042383	sarcolemma
0.37	GO:0005783	endoplasmic reticulum
0.34	GO:0031594	neuromuscular junction
0.33	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part

0.33

GO:0004252

tr|T1G2C4|T1G2C4_HELRO
Uncharacterized protein
Search

ACOT13

0.38	Acyl-coenzyme A thioesterase 13

0.50	GO:0051289	protein homotetramerization
0.30	GO:0008152	metabolic process

0.77	GO:0047617	acyl-CoA hydrolase activity
0.42	GO:0004040	amidase activity
0.41	GO:0016758	transferase activity, transferring hexosyl groups

0.42	GO:0005737	cytoplasm
0.39	GO:0043231	intracellular membrane-bounded organelle

0.77

EC:3.1.2 EC:3.1.2.20

GO:0047617

tr|T1G2C5|T1G2C5_HELRO
Kinesin-like protein
Search

0.74	GO:0007018	microtubule-based movement
0.46	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity
0.45	GO:0030705	cytoskeleton-dependent intracellular transport
0.45	GO:0035617	stress granule disassembly
0.45	GO:0007317	regulation of pole plasm oskar mRNA localization
0.45	GO:0045451	pole plasm oskar mRNA localization
0.45	GO:0007097	nuclear migration
0.45	GO:0008345	larval locomotory behavior
0.45	GO:0007310	oocyte dorsal/ventral axis specification
0.45	GO:0046843	dorsal appendage formation

0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0005523	tropomyosin binding
0.39	GO:0042623	ATPase activity, coupled
0.37	GO:0022853	active ion transmembrane transporter activity
0.36	GO:0015405	P-P-bond-hydrolysis-driven transmembrane transporter activity

0.69	GO:0005874	microtubule
0.45	GO:0005871	kinesin complex
0.45	GO:0030478	actin cap
0.45	GO:0032839	dendrite cytoplasm
0.44	GO:1904115	axon cytoplasm
0.42	GO:0045202	synapse
0.40	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)
0.35	GO:0005635	nuclear envelope
0.33	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

tr|T1G2C6|T1G2C6_HELRO
Uncharacterized protein
Search

0.40	Nuclear transport factor

tr|T1G2C7|T1G2C7_HELRO
Uncharacterized protein
Search

0.50	Myeloid/lymphoid or mixed-lineage leukemia (Trithorax homolog) (Fragment)

0.61	GO:0060729	intestinal epithelial structure maintenance
0.58	GO:0060070	canonical Wnt signaling pathway
0.52	GO:2001161	negative regulation of histone H3-K79 methylation
0.52	GO:0035812	renal sodium excretion
0.52	GO:0036359	renal potassium excretion
0.52	GO:0035811	negative regulation of urine volume
0.50	GO:0010765	positive regulation of sodium ion transport
0.49	GO:0045944	positive regulation of transcription by RNA polymerase II

0.54

GO:0046872

metal ion binding

0.41	GO:0005654	nucleoplasm
0.41	GO:0005829	cytosol
0.38	GO:0043234	protein complex

tr|T1G2C8|T1G2C8_HELRO
Uncharacterized protein
Search

0.42	GO:0071230	cellular response to amino acid stimulus
0.41	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.41	GO:0052548	regulation of endopeptidase activity
0.41	GO:0010466	negative regulation of peptidase activity
0.41	GO:0030198	extracellular matrix organization
0.41	GO:0007275	multicellular organism development
0.40	GO:0009653	anatomical structure morphogenesis
0.40	GO:0007155	cell adhesion
0.39	GO:0009888	tissue development
0.39	GO:0033622	integrin activation

0.62	GO:0005201	extracellular matrix structural constituent
0.46	GO:0042302	structural constituent of cuticle
0.41	GO:0004867	serine-type endopeptidase inhibitor activity
0.39	GO:0005178	integrin binding
0.38	GO:0048407	platelet-derived growth factor binding
0.36	GO:0042802	identical protein binding
0.34	GO:0046332	SMAD binding
0.34	GO:0005509	calcium ion binding
0.33	GO:0097493	structural molecule activity conferring elasticity
0.32	GO:0008488	gamma-glutamyl carboxylase activity

0.64	GO:0005581	collagen trimer
0.55	GO:0044420	extracellular matrix component
0.53	GO:0005578	proteinaceous extracellular matrix
0.39	GO:0099080	supramolecular complex
0.38	GO:0005615	extracellular space
0.35	GO:0031594	neuromuscular junction
0.34	GO:0005783	endoplasmic reticulum
0.33	GO:0070013	intracellular organelle lumen
0.33	GO:0005938	cell cortex
0.33	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane

0.32

EC:4.1.1

GO:0008488

tr|T1G2C9|T1G2C9_HELRO
Uncharacterized protein
Search

0.68	Phosphofurin acidic cluster sorting protein 2

0.36	GO:0097421	liver regeneration
0.35	GO:0008380	RNA splicing
0.35	GO:0033120	positive regulation of RNA splicing
0.35	GO:0007506	gonadal mesoderm development
0.35	GO:0032869	cellular response to insulin stimulus
0.35	GO:0040009	regulation of growth rate
0.35	GO:0006397	mRNA processing
0.35	GO:0002119	nematode larval development
0.35	GO:0009611	response to wounding
0.34	GO:0007283	spermatogenesis

0.59	GO:0003723	RNA binding
0.36	GO:0050733	RS domain binding
0.36	GO:0043422	protein kinase B binding
0.34	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.33	GO:0004730	pseudouridylate synthase activity

0.36	GO:0005730	nucleolus
0.35	GO:0005829	cytosol
0.35	GO:0016607	nuclear speck
0.30	GO:0031224	intrinsic component of membrane

0.34	EC:2.7.7.6	GO:0003899
0.33	KEGG:R01055	GO:0004730

tr|T1G2D0|T1G2D0_HELRO
Uncharacterized protein
Search

PGPEP1

0.65	Pyroglutamyl-peptidase 1 pyroglutamyl-peptidase i pyrrolidone-carboxylate peptidase pgp-i pyroglutamyl aminopeptidase i pap-i

0.60	GO:0006508	proteolysis
0.31	GO:2001141	regulation of RNA biosynthetic process
0.31	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.31	GO:0010468	regulation of gene expression

0.82	GO:0016920	pyroglutamyl-peptidase activity
0.39	GO:0004177	aminopeptidase activity
0.35	GO:0008234	cysteine-type peptidase activity
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0019001	guanyl nucleotide binding
0.32	GO:0003700	DNA binding transcription factor activity
0.31	GO:0032553	ribonucleotide binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.67

GO:0005829

cytosol

0.82

EC:3.4.19

GO:0016920

tr|T1G2D1|T1G2D1_HELRO
Uncharacterized protein
Search

UPRT

0.44	Uracil phosphoribosyltransferase

0.66	GO:0009116	nucleoside metabolic process
0.44	GO:0008655	pyrimidine-containing compound salvage
0.43	GO:0009174	pyrimidine ribonucleoside monophosphate biosynthetic process
0.43	GO:0006206	pyrimidine nucleobase metabolic process
0.43	GO:0009218	pyrimidine ribonucleotide metabolic process
0.42	GO:0006221	pyrimidine nucleotide biosynthetic process
0.42	GO:1901659	glycosyl compound biosynthetic process
0.41	GO:0009260	ribonucleotide biosynthetic process
0.36	GO:0007595	lactation
0.36	GO:0007565	female pregnancy

0.55	GO:0016757	transferase activity, transferring glycosyl groups
0.45	GO:0004849	uridine kinase activity
0.36	GO:0032550	purine ribonucleoside binding
0.36	GO:0032561	guanyl ribonucleotide binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005515	protein binding

0.42	GO:0005829	cytosol
0.35	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.55

GO:0016757

tr|T1G2D2|T1G2D2_HELRO
Galactoside 2-alpha-L-fucosyltransferase
Search

0.50	Galactoside 2-alpha-L-fucosyltransferase

0.81	GO:0036065	fucosylation
0.74	GO:0043413	macromolecule glycosylation
0.74	GO:0009101	glycoprotein biosynthetic process
0.60	GO:0005975	carbohydrate metabolic process
0.60	GO:0006464	cellular protein modification process

0.84

GO:0008107

galactoside 2-alpha-L-fucosyltransferase activity

0.81	GO:0032580	Golgi cisterna membrane
0.30	GO:0016021	integral component of membrane

0.84

EC:2.4.1.69

GO:0008107

tr|T1G2D3|T1G2D3_HELRO
Uncharacterized protein
Search

tr|T1G2D4|T1G2D4_HELRO
Uncharacterized protein
Search

0.39	Serine/threonine-protein kinase RIO1

0.63	GO:0006468	protein phosphorylation
0.39	GO:2000234	positive regulation of rRNA processing
0.39	GO:0016479	negative regulation of transcription by RNA polymerase I
0.38	GO:0007096	regulation of exit from mitosis
0.38	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.35	GO:0060252	positive regulation of glial cell proliferation
0.34	GO:0036093	germ cell proliferation
0.34	GO:0040026	positive regulation of vulval development
0.33	GO:0002119	nematode larval development
0.33	GO:0046579	positive regulation of Ras protein signal transduction

0.70	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0004252	serine-type endopeptidase activity

0.39	GO:0030874	nucleolar chromatin
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.70

GO:0004674

tr|T1G2D5|T1G2D5_HELRO
Palmitoyltransferase
Search

0.23	Palmitoyltransferase

0.50	GO:0018345	protein palmitoylation
0.34	GO:0000027	ribosomal large subunit assembly
0.33	GO:0006508	proteolysis

0.80	GO:0019706	protein-cysteine S-palmitoyltransferase activity
0.33	GO:0004252	serine-type endopeptidase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.49	GO:0005783	endoplasmic reticulum
0.45	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.44	GO:0031984	organelle subcompartment
0.35	GO:0005794	Golgi apparatus
0.30	GO:0016021	integral component of membrane

0.80

GO:0019706

tr|T1G2D6|T1G2D6_HELRO
Uncharacterized protein
Search

0.87	Arf-GAP with dual PH domain-containing protein 1

0.76	GO:0043547	positive regulation of GTPase activity
0.37	GO:0048016	inositol phosphate-mediated signaling
0.33	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:0007166	cell surface receptor signaling pathway
0.32	GO:2001141	regulation of RNA biosynthetic process
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression
0.31	GO:0006807	nitrogen compound metabolic process

0.83	GO:1902936	phosphatidylinositol bisphosphate binding
0.76	GO:0005096	GTPase activator activity
0.50	GO:0046872	metal ion binding
0.39	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.35	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding
0.33	GO:0004930	G-protein coupled receptor activity
0.33	GO:0003924	GTPase activity
0.33	GO:0043565	sequence-specific DNA binding
0.33	GO:0005515	protein binding
0.33	GO:0032550	purine ribonucleoside binding

0.43	GO:0005829	cytosol
0.41	GO:0005634	nucleus
0.39	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1G2D7|T1G2D7_HELRO
Uncharacterized protein
Search

0.24	Glutamine synthetase family protein

0.44	GO:0033622	integrin activation
0.43	GO:0051894	positive regulation of focal adhesion assembly
0.43	GO:0033627	cell adhesion mediated by integrin
0.42	GO:0071230	cellular response to amino acid stimulus
0.39	GO:0000160	phosphorelay signal transduction system
0.39	GO:0006413	translational initiation

0.44	GO:0005199	structural constituent of cell wall
0.43	GO:0005178	integrin binding
0.42	GO:0005201	extracellular matrix structural constituent
0.39	GO:0003743	translation initiation factor activity

0.55	GO:0005581	collagen trimer
0.44	GO:0031012	extracellular matrix
0.34	GO:0005622	intracellular
0.30	GO:0016020	membrane

tr|T1G2D8|T1G2D8_HELRO
Uncharacterized protein
Search

0.50	GO:0030509	BMP signaling pathway
0.50	GO:0048513	animal organ development
0.49	GO:0060828	regulation of canonical Wnt signaling pathway
0.49	GO:0070447	positive regulation of oligodendrocyte progenitor proliferation
0.48	GO:0140058	neuron projection arborization
0.48	GO:1904447	folic acid import across plasma membrane
0.47	GO:0061156	pulmonary artery morphogenesis
0.46	GO:0035904	aorta development
0.46	GO:0030514	negative regulation of BMP signaling pathway
0.46	GO:0001843	neural tube closure

0.65	GO:0005509	calcium ion binding
0.43	GO:0004252	serine-type endopeptidase activity
0.39	GO:0030229	very-low-density lipoprotein particle receptor activity
0.35	GO:0017147	Wnt-protein binding
0.35	GO:0042813	Wnt-activated receptor activity
0.34	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0008144	drug binding

0.46	GO:0031526	brush border membrane
0.45	GO:0016324	apical plasma membrane
0.45	GO:0009897	external side of plasma membrane
0.45	GO:0030139	endocytic vesicle
0.44	GO:0005905	clathrin-coated pit
0.44	GO:0030425	dendrite
0.44	GO:0030424	axon
0.44	GO:0043235	receptor complex
0.43	GO:0005768	endosome
0.42	GO:0005794	Golgi apparatus

0.43

GO:0004252

tr|T1G2D9|T1G2D9_HELRO
Uncharacterized protein
Search

0.51	GO:0034158	toll-like receptor 8 signaling pathway
0.48	GO:0002755	MyD88-dependent toll-like receptor signaling pathway
0.48	GO:0050707	regulation of cytokine secretion
0.47	GO:0006954	inflammatory response
0.47	GO:0045087	innate immune response
0.46	GO:0051607	defense response to virus
0.46	GO:0016310	phosphorylation
0.44	GO:0036211	protein modification process
0.42	GO:0044267	cellular protein metabolic process

0.47	GO:0016301	kinase activity
0.47	GO:0003727	single-stranded RNA binding
0.46	GO:0005509	calcium ion binding
0.46	GO:0003725	double-stranded RNA binding
0.44	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.43	GO:0140096	catalytic activity, acting on a protein
0.41	GO:0032559	adenyl ribonucleotide binding
0.41	GO:0008144	drug binding
0.41	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0003677	DNA binding

0.30

GO:0016020

membrane

0.44

GO:0016773

tr|T1G2E0|T1G2E0_HELRO
Uncharacterized protein
Search

0.69	Adipose triglyceride lipase brummer

0.72	GO:0016042	lipid catabolic process
0.54	GO:0010898	positive regulation of triglyceride catabolic process
0.45	GO:0055088	lipid homeostasis
0.45	GO:0006641	triglyceride metabolic process
0.45	GO:0010891	negative regulation of sequestering of triglyceride
0.44	GO:0010884	positive regulation of lipid storage
0.39	GO:0044248	cellular catabolic process
0.37	GO:0001889	liver development
0.35	GO:0071805	potassium ion transmembrane transport
0.33	GO:0006397	mRNA processing

0.55	GO:0004806	triglyceride lipase activity
0.35	GO:0005267	potassium channel activity
0.33	GO:0003723	RNA binding

0.46	GO:0005811	lipid droplet
0.34	GO:0005829	cytosol
0.34	GO:0005634	nucleus
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.55

EC:3.1.1.3

GO:0004806

tr|T1G2E1|T1G2E1_HELRO
Uncharacterized protein
Search

tr|T1G2E2|T1G2E2_HELRO
Uncharacterized protein
Search

0.51	GO:0003676	nucleic acid binding
0.38	GO:0046872	metal ion binding

tr|T1G2E3|T1G2E3_HELRO
Uncharacterized protein
Search

0.10	Collagen type IX alpha 1 (Fragment)

0.46	GO:1903225	negative regulation of endodermal cell differentiation
0.45	GO:0030199	collagen fibril organization
0.45	GO:0009653	anatomical structure morphogenesis
0.45	GO:0071230	cellular response to amino acid stimulus
0.45	GO:0007275	multicellular organism development
0.39	GO:0030154	cell differentiation
0.39	GO:0009888	tissue development
0.38	GO:0010951	negative regulation of endopeptidase activity
0.37	GO:0031099	regeneration
0.37	GO:0042060	wound healing

0.68	GO:0005201	extracellular matrix structural constituent
0.44	GO:0046332	SMAD binding
0.40	GO:0042302	structural constituent of cuticle
0.38	GO:0004867	serine-type endopeptidase inhibitor activity
0.35	GO:0048407	platelet-derived growth factor binding
0.35	GO:0042802	identical protein binding
0.35	GO:0005178	integrin binding
0.34	GO:0002020	protease binding
0.33	GO:0005044	scavenger receptor activity
0.33	GO:0030674	protein binding, bridging

0.61	GO:0005581	collagen trimer
0.49	GO:0044420	extracellular matrix component
0.47	GO:0005578	proteinaceous extracellular matrix
0.42	GO:0005615	extracellular space
0.42	GO:0099081	supramolecular polymer
0.38	GO:0005783	endoplasmic reticulum
0.34	GO:0000139	Golgi membrane
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0019867	outer membrane
0.32	GO:0070013	intracellular organelle lumen

0.32

GO:0008168

tr|T1G2E4|T1G2E4_HELRO
Bestrophin homolog
Search

BEST2

0.62	Bestrophin

0.76	GO:1902476	chloride transmembrane transport
0.51	GO:0043271	negative regulation of ion transport
0.51	GO:0007601	visual perception
0.37	GO:0051899	membrane depolarization
0.36	GO:0050962	detection of light stimulus involved in sensory perception
0.36	GO:0007608	sensory perception of smell
0.36	GO:0051924	regulation of calcium ion transport
0.36	GO:0009584	detection of visible light
0.35	GO:0030321	transepithelial chloride transport
0.34	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay

0.77	GO:0005254	chloride channel activity
0.34	GO:0042802	identical protein binding

0.81	GO:0034707	chloride channel complex
0.55	GO:0005886	plasma membrane
0.36	GO:0005929	cilium

tr|T1G2E5|T1G2E5_HELRO
Uncharacterized protein
Search

0.52	Kinesin heavy chain

0.74	GO:0007018	microtubule-based movement
0.51	GO:0035617	stress granule disassembly
0.49	GO:0007028	cytoplasm organization
0.49	GO:0030705	cytoskeleton-dependent intracellular transport
0.47	GO:0051650	establishment of vesicle localization
0.47	GO:0007411	axon guidance
0.45	GO:0032230	positive regulation of synaptic transmission, GABAergic
0.45	GO:0060341	regulation of cellular localization
0.45	GO:0051642	centrosome localization
0.44	GO:0071346	cellular response to interferon-gamma

0.75	GO:0003777	microtubule motor activity
0.72	GO:0008017	microtubule binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0042623	ATPase activity, coupled
0.43	GO:0045296	cadherin binding
0.42	GO:0005523	tropomyosin binding
0.42	GO:0022853	active ion transmembrane transporter activity

0.67	GO:0005874	microtubule
0.47	GO:0043005	neuron projection
0.47	GO:0035253	ciliary rootlet
0.47	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)
0.47	GO:0005871	kinesin complex
0.44	GO:0045335	phagocytic vesicle
0.43	GO:0030478	actin cap
0.42	GO:0005815	microtubule organizing center
0.41	GO:0032838	plasma membrane bounded cell projection cytoplasm
0.41	GO:0036477	somatodendritic compartment

tr|T1G2E6|T1G2E6_HELRO
Uncharacterized protein
Search

CWF19L2

0.77	CWF19 like 2, cell cycle control (S. pombe)

0.56

GO:0006468

protein phosphorylation

0.56	GO:0004672	protein kinase activity
0.49	GO:0030554	adenyl nucleotide binding
0.49	GO:0097367	carbohydrate derivative binding
0.49	GO:0008144	drug binding
0.49	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0031224

intrinsic component of membrane

tr|T1G2E7|T1G2E7_HELRO
Uncharacterized protein
Search

0.10	Low-density lipoprotein receptor domain class A (Fragment)

0.42	GO:0032370	positive regulation of lipid transport
0.41	GO:0007165	signal transduction
0.40	GO:0034220	ion transmembrane transport
0.39	GO:0006508	proteolysis
0.38	GO:0006898	receptor-mediated endocytosis
0.37	GO:0007275	multicellular organism development
0.37	GO:0071773	cellular response to BMP stimulus
0.37	GO:0060828	regulation of canonical Wnt signaling pathway
0.36	GO:0006357	regulation of transcription by RNA polymerase II
0.35	GO:0015884	folic acid transport

0.58	GO:0005509	calcium ion binding
0.45	GO:0005230	extracellular ligand-gated ion channel activity
0.43	GO:0004888	transmembrane signaling receptor activity
0.43	GO:0071813	lipoprotein particle binding
0.41	GO:0004252	serine-type endopeptidase activity
0.39	GO:0005044	scavenger receptor activity
0.33	GO:0005515	protein binding

0.37	GO:0005794	Golgi apparatus
0.36	GO:0005886	plasma membrane
0.35	GO:0031410	cytoplasmic vesicle
0.34	GO:0005903	brush border
0.34	GO:0005905	clathrin-coated pit
0.34	GO:0030425	dendrite
0.34	GO:0045177	apical part of cell
0.34	GO:0030424	axon
0.34	GO:0043235	receptor complex
0.34	GO:0009986	cell surface

0.41

GO:0004252

tr|T1G2E8|T1G2E8_HELRO
Uncharacterized protein
Search

0.93	Sodium-potassium ATPase beta

0.73	GO:0006814	sodium ion transport
0.71	GO:0006813	potassium ion transport
0.46	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient
0.46	GO:0007605	sensory perception of sound
0.44	GO:0035158	regulation of tube diameter, open tracheal system
0.44	GO:0060857	establishment of glial blood-brain barrier
0.44	GO:0061343	cell adhesion involved in heart morphogenesis
0.44	GO:0090662	ATP hydrolysis coupled transmembrane transport
0.44	GO:0019991	septate junction assembly
0.42	GO:0010996	response to auditory stimulus

0.46	GO:0005391	sodium:potassium-exchanging ATPase activity
0.35	GO:0005267	potassium channel activity
0.34	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
0.33	GO:0005509	calcium ion binding

0.85	GO:0005890	sodium:potassium-exchanging ATPase complex
0.43	GO:0005918	septate junction
0.41	GO:0030424	axon

0.46	EC:3.6.3.9	GO:0005391
0.34	KEGG:R05982 KEGG:R06722	GO:0004571

tr|T1G2E9|T1G2E9_HELRO
Uncharacterized protein
Search

0.44	GO:0030198	extracellular matrix organization
0.43	GO:0048731	system development
0.40	GO:0009653	anatomical structure morphogenesis
0.40	GO:0009888	tissue development
0.39	GO:0030154	cell differentiation
0.39	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.38	GO:0097435	supramolecular fiber organization
0.38	GO:0071230	cellular response to amino acid stimulus
0.37	GO:0007605	sensory perception of sound
0.37	GO:0048589	developmental growth

0.66	GO:0005201	extracellular matrix structural constituent
0.41	GO:0042302	structural constituent of cuticle
0.39	GO:0048407	platelet-derived growth factor binding
0.37	GO:0043394	proteoglycan binding
0.37	GO:0008201	heparin binding
0.36	GO:0030414	peptidase inhibitor activity
0.36	GO:0061135	endopeptidase regulator activity
0.34	GO:0008270	zinc ion binding
0.34	GO:0005044	scavenger receptor activity
0.34	GO:0005178	integrin binding

0.65	GO:0005581	collagen trimer
0.51	GO:0044420	extracellular matrix component
0.49	GO:0005578	proteinaceous extracellular matrix
0.39	GO:0099081	supramolecular polymer
0.36	GO:0005615	extracellular space
0.34	GO:0005783	endoplasmic reticulum
0.33	GO:0070013	intracellular organelle lumen
0.32	GO:0005938	cell cortex
0.32	GO:0044446	intracellular organelle part
0.32	GO:0005840	ribosome

0.32

EC:2.3.1

GO:0008374

tr|T1G2F0|T1G2F0_HELRO
Uncharacterized protein
Search

0.45	GO:0030198	extracellular matrix organization
0.45	GO:0007167	enzyme linked receptor protein signaling pathway
0.44	GO:0043589	skin morphogenesis
0.44	GO:0070208	protein heterotrimerization
0.43	GO:0071560	cellular response to transforming growth factor beta stimulus
0.43	GO:0071230	cellular response to amino acid stimulus
0.43	GO:0038065	collagen-activated signaling pathway
0.42	GO:0007266	Rho protein signal transduction
0.42	GO:0001501	skeletal system development
0.42	GO:0001568	blood vessel development

0.72	GO:0005201	extracellular matrix structural constituent
0.44	GO:0048407	platelet-derived growth factor binding
0.43	GO:0002020	protease binding
0.42	GO:0046332	SMAD binding
0.41	GO:0030674	protein binding, bridging
0.41	GO:0042302	structural constituent of cuticle
0.40	GO:0042802	identical protein binding
0.39	GO:0008201	heparin binding
0.34	GO:0030414	peptidase inhibitor activity
0.34	GO:0046872	metal ion binding

0.69	GO:0005581	collagen trimer
0.65	GO:0044420	extracellular matrix component
0.61	GO:0005578	proteinaceous extracellular matrix
0.46	GO:0099081	supramolecular polymer
0.41	GO:0005615	extracellular space
0.40	GO:0031594	neuromuscular junction
0.39	GO:0005783	endoplasmic reticulum
0.35	GO:0019867	outer membrane
0.34	GO:1903561	extracellular vesicle
0.33	GO:0070013	intracellular organelle lumen

0.32

EC:3.1.1.74

GO:0050525

tr|T1G2F1|T1G2F1_HELRO
Uncharacterized protein
Search

tr|T1G2F2|T1G2F2_HELRO
Uncharacterized protein
Search

0.77	Putative pattern-formation protein/guanine nucleotide exchange factor

0.81	GO:0032012	regulation of ARF protein signal transduction
0.66	GO:0065009	regulation of molecular function
0.42	GO:0008586	imaginal disc-derived wing vein morphogenesis
0.42	GO:0040018	positive regulation of multicellular organism growth
0.42	GO:0001700	embryonic development via the syncytial blastoderm
0.41	GO:0030100	regulation of endocytosis
0.41	GO:0110020	regulation of actomyosin structure organization
0.41	GO:0043410	positive regulation of MAPK cascade
0.40	GO:0016331	morphogenesis of embryonic epithelium
0.36	GO:0046579	positive regulation of Ras protein signal transduction

0.82	GO:0005086	ARF guanyl-nucleotide exchange factor activity
0.42	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.40	GO:0042803	protein homodimerization activity
0.35	GO:0003743	translation initiation factor activity
0.34	GO:0034450	ubiquitin-ubiquitin ligase activity
0.34	GO:0008061	chitin binding
0.33	GO:0016791	phosphatase activity
0.33	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds

0.43	GO:1904269	cell leading edge cell cortex
0.42	GO:0032154	cleavage furrow
0.41	GO:0070938	contractile ring
0.41	GO:0005913	cell-cell adherens junction
0.36	GO:0005886	plasma membrane
0.35	GO:0005852	eukaryotic translation initiation factor 3 complex
0.35	GO:0000139	Golgi membrane
0.34	GO:0005829	cytosol
0.34	GO:0000151	ubiquitin ligase complex
0.33	GO:0005576	extracellular region

0.33

EC:3.1.3 EC:3.1.3.41

GO:0016791

tr|T1G2F3|T1G2F3_HELRO
Uncharacterized protein
Search

0.40	Collagen triple helix repeat-containing protein (Fragment)

0.52	GO:0030199	collagen fibril organization
0.49	GO:0001501	skeletal system development
0.48	GO:0061448	connective tissue development
0.48	GO:0009887	animal organ morphogenesis
0.48	GO:0001894	tissue homeostasis
0.48	GO:0007605	sensory perception of sound
0.45	GO:0030154	cell differentiation
0.42	GO:1903225	negative regulation of endodermal cell differentiation
0.40	GO:0043588	skin development
0.40	GO:0060023	soft palate development

0.69	GO:0005201	extracellular matrix structural constituent
0.41	GO:0042302	structural constituent of cuticle
0.39	GO:0046332	SMAD binding
0.34	GO:0005044	scavenger receptor activity
0.34	GO:0030674	protein binding, bridging
0.33	GO:0046872	metal ion binding
0.33	GO:0030246	carbohydrate binding
0.32	GO:0000155	phosphorelay sensor kinase activity
0.32	GO:0016787	hydrolase activity
0.31	GO:0003677	DNA binding

0.63	GO:0005581	collagen trimer
0.47	GO:0044420	extracellular matrix component
0.46	GO:0005578	proteinaceous extracellular matrix
0.39	GO:0099081	supramolecular polymer
0.38	GO:0005615	extracellular space
0.37	GO:0019867	outer membrane
0.34	GO:0005788	endoplasmic reticulum lumen
0.34	GO:0031594	neuromuscular junction
0.33	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.32

EC:2.7.3

GO:0000155

tr|T1G2F4|T1G2F4_HELRO
Uncharacterized protein
Search

0.71	Synaptogyrin

0.42	GO:0032411	positive regulation of transporter activity
0.41	GO:0045055	regulated exocytosis
0.35	GO:0006470	protein dephosphorylation
0.34	GO:0015886	heme transport
0.33	GO:0016310	phosphorylation

0.42	GO:0042169	SH2 domain binding
0.42	GO:0047485	protein N-terminus binding
0.35	GO:0004722	protein serine/threonine phosphatase activity
0.34	GO:0015232	heme transporter activity
0.33	GO:0016301	kinase activity

0.49	GO:0031594	neuromuscular junction
0.47	GO:0008021	synaptic vesicle
0.47	GO:0099501	exocytic vesicle membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1G2F5|T1G2F5_HELRO
Uncharacterized protein
Search

0.58	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.53	GO:0006468	protein phosphorylation
0.50	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.50	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.49	GO:0007605	sensory perception of sound
0.49	GO:0048839	inner ear development
0.48	GO:0016055	Wnt signaling pathway
0.38	GO:2000027	regulation of organ morphogenesis
0.38	GO:1905490	negative regulation of sensory neuron axon guidance
0.38	GO:1905815	regulation of dorsal/ventral axon guidance

0.53	GO:0004672	protein kinase activity
0.51	GO:0017147	Wnt-protein binding
0.51	GO:0042813	Wnt-activated receptor activity
0.49	GO:0005509	calcium ion binding
0.47	GO:0030554	adenyl nucleotide binding
0.46	GO:0097367	carbohydrate derivative binding
0.46	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0008144	drug binding
0.36	GO:1904929	coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway
0.35	GO:0019904	protein domain specific binding

0.50	GO:0043679	axon terminus
0.49	GO:0043235	receptor complex
0.40	GO:0005886	plasma membrane
0.36	GO:0001725	stress fiber
0.35	GO:0030424	axon
0.35	GO:0009986	cell surface
0.32	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

tr|T1G2F6|T1G2F6_HELRO
Uncharacterized protein
Search

0.53	Homeobox protein ceh-5 (inferred by orthology to a C. elegans protein)

0.65	GO:0048513	animal organ development
0.64	GO:0009653	anatomical structure morphogenesis
0.63	GO:0061564	axon development
0.63	GO:0060322	head development
0.63	GO:0007417	central nervous system development
0.57	GO:0007601	visual perception
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0009790	embryo development
0.56	GO:0010468	regulation of gene expression

0.64	GO:0043565	sequence-specific DNA binding
0.57	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding
0.55	GO:0003700	DNA binding transcription factor activity
0.54	GO:0031490	chromatin DNA binding
0.51	GO:0001012	RNA polymerase II regulatory region DNA binding
0.49	GO:0003690	double-stranded DNA binding
0.33	GO:0008289	lipid binding
0.32	GO:0046872	metal ion binding
0.32	GO:0016787	hydrolase activity

0.61	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm

0.32

GO:0016787

tr|T1G2F7|T1G2F7_HELRO
Uncharacterized protein
Search

TMPPE

0.22	Transmembrane protein with metallophosphoesterase domain

0.32

GO:0090305

nucleic acid phosphodiester bond hydrolysis

0.51	GO:0016787	hydrolase activity
0.34	GO:0046872	metal ion binding
0.32	GO:0003676	nucleic acid binding

0.30

GO:0044425

membrane part

0.51

GO:0016787

tr|T1G2F8|T1G2F8_HELRO
Uncharacterized protein
Search

tr|T1G2F9|T1G2F9_HELRO
Cytochrome b-c1 complex subunit 7
Search

0.67	Cytochrome b-c1 complex subunit

0.74	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c
0.39	GO:0017062	respiratory chain complex III assembly
0.39	GO:0097033	mitochondrial respiratory chain complex III biogenesis
0.39	GO:0033108	mitochondrial respiratory chain complex assembly
0.38	GO:0006757	ATP generation from ADP
0.38	GO:0006090	pyruvate metabolic process
0.38	GO:0016052	carbohydrate catabolic process
0.38	GO:0019362	pyridine nucleotide metabolic process
0.37	GO:0001525	angiogenesis
0.36	GO:0009060	aerobic respiration

0.40	GO:0004634	phosphopyruvate hydratase activity
0.39	GO:0016681	oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor
0.37	GO:0000287	magnesium ion binding
0.37	GO:0009055	electron transfer activity
0.33	GO:0004672	protein kinase activity
0.33	GO:0003723	RNA binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.83	GO:0005750	mitochondrial respiratory chain complex III
0.39	GO:0000015	phosphopyruvate hydratase complex

0.40

EC:4.2.1.11

GO:0004634

tr|T1G2G0|T1G2G0_HELRO
Uncharacterized protein
Search

0.10	phosphatidylinositol 3-kinase regulatory subunit gamma-like

0.85	GO:0043551	regulation of phosphatidylinositol 3-kinase activity
0.52	GO:0007165	signal transduction
0.51	GO:0016310	phosphorylation
0.46	GO:0032869	cellular response to insulin stimulus
0.42	GO:0042993	positive regulation of transcription factor import into nucleus
0.42	GO:1903076	regulation of protein localization to plasma membrane
0.42	GO:0051492	regulation of stress fiber assembly
0.41	GO:0001678	cellular glucose homeostasis
0.41	GO:0034976	response to endoplasmic reticulum stress
0.40	GO:0046488	phosphatidylinositol metabolic process

0.85	GO:0035014	phosphatidylinositol 3-kinase regulator activity
0.53	GO:0016301	kinase activity
0.43	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding
0.39	GO:0046982	protein heterodimerization activity
0.39	GO:0008134	transcription factor binding
0.35	GO:0046872	metal ion binding

0.83	GO:0005942	phosphatidylinositol 3-kinase complex
0.41	GO:0005925	focal adhesion
0.37	GO:0005634	nucleus

tr|T1G2G1|T1G2G1_HELRO
Uncharacterized protein
Search

0.50	GO:0046872	metal ion binding
0.42	GO:0003676	nucleic acid binding

0.45

GO:0005634

nucleus

tr|T1G2G2|T1G2G2_HELRO
Uncharacterized protein
Search

TMEM170A

0.94	Transmembrane domain-containing protein (Fragment)

0.49	GO:0071786	endoplasmic reticulum tubular network organization
0.46	GO:0051292	nuclear pore complex assembly
0.45	GO:0006998	nuclear envelope organization

0.33

GO:0005515

protein binding

0.45	GO:0005635	nuclear envelope
0.44	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1G2G3|T1G2G3_HELRO
Uncharacterized protein
Search

0.67	Transport protein particle trapp complex subunit

0.76	GO:0048193	Golgi vesicle transport
0.34	GO:0006901	vesicle coating
0.34	GO:0046907	intracellular transport
0.34	GO:0006903	vesicle targeting
0.34	GO:0006264	mitochondrial DNA replication
0.34	GO:0065009	regulation of molecular function
0.34	GO:0071897	DNA biosynthetic process
0.33	GO:0035335	peptidyl-tyrosine dephosphorylation
0.33	GO:0006461	protein complex assembly
0.33	GO:0090305	nucleic acid phosphodiester bond hydrolysis

0.36	GO:0017112	Rab guanyl-nucleotide exchange factor activity
0.34	GO:0003887	DNA-directed DNA polymerase activity
0.33	GO:0004725	protein tyrosine phosphatase activity
0.33	GO:0005509	calcium ion binding
0.33	GO:0008408	3'-5' exonuclease activity
0.33	GO:0003677	DNA binding

0.82	GO:0030008	TRAPP complex
0.36	GO:0005760	gamma DNA polymerase complex
0.35	GO:0005794	Golgi apparatus
0.35	GO:0005783	endoplasmic reticulum
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0005829	cytosol
0.33	GO:0031984	organelle subcompartment
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:2.7.7.7

GO:0003887

tr|T1G2G4|T1G2G4_HELRO
Uncharacterized protein
Search

0.61	Chitin synthase variant

0.39	GO:0006038	cell wall chitin biosynthetic process
0.37	GO:0006035	cuticle chitin biosynthetic process
0.34	GO:0007018	microtubule-based movement
0.34	GO:0009792	embryo development ending in birth or egg hatching
0.33	GO:0055085	transmembrane transport
0.33	GO:0006508	proteolysis

0.69	GO:0016758	transferase activity, transferring hexosyl groups
0.38	GO:0008194	UDP-glycosyltransferase activity
0.35	GO:0003779	actin binding
0.35	GO:0003774	motor activity
0.34	GO:0008017	microtubule binding
0.33	GO:0004222	metalloendopeptidase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0005215	transporter activity
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.38	GO:0030428	cell septum
0.35	GO:0016459	myosin complex
0.34	GO:0071944	cell periphery
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0016758

tr|T1G2G5|T1G2G5_HELRO
Uncharacterized protein
Search

0.61	GO:0007165	signal transduction
0.60	GO:0034220	ion transmembrane transport
0.57	GO:0060078	regulation of postsynaptic membrane potential
0.55	GO:0007268	chemical synaptic transmission
0.35	GO:0042595	behavioral response to starvation
0.35	GO:0032000	positive regulation of fatty acid beta-oxidation
0.34	GO:0006821	chloride transport
0.33	GO:0006812	cation transport

0.76	GO:0005230	extracellular ligand-gated ion channel activity
0.70	GO:0004888	transmembrane signaling receptor activity
0.58	GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential
0.55	GO:0022835	transmitter-gated channel activity
0.54	GO:0140135	mechanosensitive cation channel activity
0.34	GO:0005254	chloride channel activity

0.56	GO:0045211	postsynaptic membrane
0.53	GO:0030054	cell junction
0.34	GO:0043025	neuronal cell body
0.30	GO:0016021	integral component of membrane

tr|T1G2G6|T1G2G6_HELRO
Uncharacterized protein
Search

0.63	GO:0006468	protein phosphorylation
0.42	GO:0071689	muscle thin filament assembly
0.41	GO:0045214	sarcomere organization
0.40	GO:0007498	mesoderm development
0.35	GO:0072428	signal transduction involved in intra-S DNA damage checkpoint
0.35	GO:0000086	G2/M transition of mitotic cell cycle
0.35	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage
0.35	GO:0090307	mitotic spindle assembly
0.35	GO:0001302	replicative cell aging
0.35	GO:0071688	striated muscle myosin thick filament assembly

0.63	GO:0004672	protein kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0008307	structural constituent of muscle
0.35	GO:0097493	structural molecule activity conferring elasticity
0.35	GO:0051371	muscle alpha-actinin binding
0.35	GO:0019899	enzyme binding
0.34	GO:0042803	protein homodimerization activity

0.41	GO:0030018	Z disc
0.35	GO:0016605	PML body
0.35	GO:0005859	muscle myosin complex
0.35	GO:0031430	M band
0.35	GO:0000781	chromosome, telomeric region
0.34	GO:0005794	Golgi apparatus
0.32	GO:0005887	integral component of plasma membrane

tr|T1G2G7|T1G2G7_HELRO
Uncharacterized protein
Search

0.47	GO:0007165	signal transduction
0.45	GO:0006468	protein phosphorylation
0.44	GO:0048749	compound eye development
0.43	GO:0045087	innate immune response
0.41	GO:0002218	activation of innate immune response
0.40	GO:0051607	defense response to virus
0.39	GO:0046426	negative regulation of JAK-STAT cascade
0.38	GO:0006469	negative regulation of protein kinase activity
0.38	GO:0071345	cellular response to cytokine stimulus
0.36	GO:0009190	cyclic nucleotide biosynthetic process

0.45	GO:0016301	kinase activity
0.44	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.43	GO:0140096	catalytic activity, acting on a protein
0.41	GO:0004888	transmembrane signaling receptor activity
0.41	GO:0032559	adenyl ribonucleotide binding
0.41	GO:0008144	drug binding
0.41	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0003727	single-stranded RNA binding
0.38	GO:0004860	protein kinase inhibitor activity
0.37	GO:0032440	2-alkenal reductase [NAD(P)] activity

0.37	GO:0005886	plasma membrane
0.36	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.44

GO:0016773

tr|T1G2G8|T1G2G8_HELRO
Uncharacterized protein
Search

0.53	GO:0043331	response to dsRNA
0.53	GO:0002224	toll-like receptor signaling pathway
0.51	GO:0045087	innate immune response
0.51	GO:0051607	defense response to virus

0.50	GO:0003725	double-stranded RNA binding
0.45	GO:0004872	receptor activity

0.46

GO:0005887

integral component of plasma membrane

tr|T1G2G9|T1G2G9_HELRO
Uncharacterized protein
Search

0.63	GO:0006468	protein phosphorylation
0.42	GO:0035556	intracellular signal transduction
0.41	GO:0007049	cell cycle
0.40	GO:0048518	positive regulation of biological process
0.40	GO:0051726	regulation of cell cycle
0.39	GO:2000352	negative regulation of endothelial cell apoptotic process
0.39	GO:0007010	cytoskeleton organization
0.39	GO:1902542	regulation of protein localization to mitotic spindle pole body
0.39	GO:0070887	cellular response to chemical stimulus
0.39	GO:1903353	regulation of nucleus organization

0.64	GO:0004672	protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0098641	cadherin binding involved in cell-cell adhesion
0.38	GO:0005057	signal transducer activity, downstream of receptor
0.38	GO:0019237	centromeric DNA binding
0.37	GO:0051219	phosphoprotein binding
0.36	GO:0048365	Rac GTPase binding

0.39	GO:1990023	mitotic spindle midzone
0.38	GO:0005913	cell-cell adherens junction
0.38	GO:0005634	nucleus
0.37	GO:0000922	spindle pole
0.37	GO:0005935	cellular bud neck
0.37	GO:0044732	mitotic spindle pole body
0.36	GO:1990385	meiotic spindle midzone
0.36	GO:0032133	chromosome passenger complex
0.36	GO:0000939	condensed chromosome inner kinetochore
0.36	GO:0005828	kinetochore microtubule

0.34

EC:3.1.3.67

GO:0016314

tr|T1G2H0|T1G2H0_HELRO
Uncharacterized protein
Search

CMC2

0.67	COX assembly mitochondrial protein 2 homolog

0.60

GO:0005739

mitochondrion

tr|T1G2H1|T1G2H1_HELRO
Uncharacterized protein
Search

RPIA

0.47	Ribose 5-phosphate isomerase A

0.80	GO:0009052	pentose-phosphate shunt, non-oxidative branch
0.46	GO:0006014	D-ribose metabolic process

0.79	GO:0004751	ribose-5-phosphate isomerase activity
0.47	GO:0042802	identical protein binding
0.36	GO:0048029	monosaccharide binding

0.42	GO:0005829	cytosol
0.38	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

0.79	EC:5.3.1.6	GO:0004751
0.79	KEGG:R01056	GO:0004751

tr|T1G2H2|T1G2H2_HELRO
Elongation of very long chain fatty acids protein
Search

ELOVL7

0.55	Elongation of very long chain fatty acids protein 7

0.74	GO:0019367	fatty acid elongation, saturated fatty acid
0.73	GO:0042761	very long-chain fatty acid biosynthetic process
0.68	GO:0019368	fatty acid elongation, unsaturated fatty acid
0.67	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process
0.63	GO:0006636	unsaturated fatty acid biosynthetic process
0.45	GO:0030148	sphingolipid biosynthetic process
0.40	GO:0048794	swim bladder development
0.40	GO:0007111	meiosis II cytokinesis
0.39	GO:0042811	pheromone biosynthetic process
0.39	GO:0007110	meiosis I cytokinesis

0.82	GO:0102756	very-long-chain 3-ketoacyl-CoA synthase activity
0.82	GO:0102338	3-oxo-lignoceronyl-CoA synthase activity
0.82	GO:0102336	3-oxo-arachidoyl-CoA synthase activity
0.82	GO:0102337	3-oxo-cerotoyl-CoA synthase activity
0.74	GO:0009922	fatty acid elongase activity
0.33	GO:0005515	protein binding

0.61	GO:0005783	endoplasmic reticulum
0.57	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.55	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.82

EC:2.3.1.199

GO:0102338

tr|T1G2H3|T1G2H3_HELRO
Uncharacterized protein
Search

0.37	GO:0006979	response to oxidative stress
0.36	GO:0098869	cellular oxidant detoxification
0.35	GO:0009651	response to salt stress
0.35	GO:0045010	actin nucleation
0.35	GO:0016560	protein import into peroxisome matrix, docking
0.34	GO:0043085	positive regulation of catalytic activity
0.34	GO:0072583	clathrin-dependent endocytosis
0.34	GO:0055114	oxidation-reduction process
0.33	GO:0016310	phosphorylation
0.33	GO:0035556	intracellular signal transduction

0.85	GO:0030156	benzodiazepine receptor binding
0.37	GO:0004601	peroxidase activity
0.36	GO:0019900	kinase binding
0.35	GO:0020037	heme binding
0.35	GO:0008017	microtubule binding
0.34	GO:0008047	enzyme activator activity
0.34	GO:0003677	DNA binding
0.34	GO:0016301	kinase activity
0.33	GO:0046872	metal ion binding

0.35	GO:0005634	nucleus
0.35	GO:0030479	actin cortical patch
0.34	GO:0005777	peroxisome
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.37	EC:1.11.1.7	GO:0004601
0.37	KEGG:R03532	GO:0004601

tr|T1G2H4|T1G2H4_HELRO
Uncharacterized protein
Search

0.39	Aminoacyl-tRNA hydrolase

0.37	GO:0010466	negative regulation of peptidase activity
0.36	GO:0016579	protein deubiquitination
0.35	GO:0006511	ubiquitin-dependent protein catabolic process
0.35	GO:0006468	protein phosphorylation
0.34	GO:0045721	negative regulation of gluconeogenesis
0.33	GO:0010498	proteasomal protein catabolic process

0.78	GO:0004045	aminoacyl-tRNA hydrolase activity
0.37	GO:0030414	peptidase inhibitor activity
0.36	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.36	GO:0004674	protein serine/threonine kinase activity
0.34	GO:0008270	zinc ion binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.36	GO:0005576	extracellular region
0.34	GO:0031966	mitochondrial membrane

0.78

EC:3.1.1.29

GO:0004045

tr|T1G2H5|T1G2H5_HELRO
Uncharacterized protein
Search

MED18

0.86	Mediator of RNA polymerase II transcription subunit 18

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.58	GO:0006351	transcription, DNA-templated
0.37	GO:0016567	protein ubiquitination
0.35	GO:0006508	proteolysis

0.79	GO:0001104	RNA polymerase II transcription cofactor activity
0.38	GO:0061630	ubiquitin protein ligase activity
0.37	GO:0005515	protein binding
0.36	GO:0008237	metallopeptidase activity

0.77	GO:0016592	mediator complex
0.51	GO:0070847	core mediator complex
0.38	GO:0000151	ubiquitin ligase complex

tr|T1G2H6|T1G2H6_HELRO
Uncharacterized protein
Search

0.68	AMPA glutamate receptor subunit 2A flop isoform (Fragment)

0.77	GO:0035235	ionotropic glutamate receptor signaling pathway
0.56	GO:0034220	ion transmembrane transport

0.77

GO:0004970

ionotropic glutamate receptor activity

0.30

GO:0016020

membrane

tr|T1G2H7|T1G2H7_HELRO
Uncharacterized protein
Search

FLAD1

0.75	Flavin adenine dinucleotide synthetase 1

0.46	GO:0072388	flavin adenine dinucleotide biosynthetic process
0.46	GO:0046443	FAD metabolic process
0.36	GO:0055114	oxidation-reduction process

0.46

GO:0003919

FMN adenylyltransferase activity

0.39	GO:0005829	cytosol
0.36	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.46	EC:2.7.7.2	GO:0003919
0.46	KEGG:R00161	GO:0003919

tr|T1G2H8|T1G2H8_HELRO
Uncharacterized protein
Search

0.48	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.44	GO:0007528	neuromuscular junction development
0.43	GO:0030198	extracellular matrix organization
0.40	GO:0071230	cellular response to amino acid stimulus
0.40	GO:0032501	multicellular organismal process
0.39	GO:0048856	anatomical structure development
0.38	GO:0030154	cell differentiation
0.37	GO:0052548	regulation of endopeptidase activity
0.36	GO:0060249	anatomical structure homeostasis
0.36	GO:0003006	developmental process involved in reproduction

0.69	GO:0005201	extracellular matrix structural constituent
0.54	GO:0042302	structural constituent of cuticle
0.36	GO:0048407	platelet-derived growth factor binding
0.36	GO:0004867	serine-type endopeptidase inhibitor activity
0.35	GO:0005178	integrin binding
0.34	GO:0005272	sodium channel activity
0.33	GO:0005509	calcium ion binding
0.32	GO:0008061	chitin binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding

0.70	GO:0005581	collagen trimer
0.66	GO:0044420	extracellular matrix component
0.62	GO:0005578	proteinaceous extracellular matrix
0.44	GO:0099081	supramolecular polymer
0.43	GO:0031594	neuromuscular junction
0.36	GO:0005615	extracellular space
0.35	GO:0005783	endoplasmic reticulum
0.34	GO:0030056	hemidesmosome
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0005938	cell cortex

tr|T1G2H9|T1G2H9_HELRO
Uncharacterized protein
Search

0.70

GO:0009966

regulation of signal transduction

0.82	GO:0046658	anchored component of plasma membrane
0.76	GO:0005578	proteinaceous extracellular matrix

tr|T1G2I0|T1G2I0_HELRO
Uncharacterized protein
Search

0.50	Phosphatidylinositol 4-kinase beta

0.79	GO:0048015	phosphatidylinositol-mediated signaling
0.74	GO:0046854	phosphatidylinositol phosphorylation
0.40	GO:0060872	semicircular canal development
0.34	GO:0006661	phosphatidylinositol biosynthetic process
0.33	GO:0006898	receptor-mediated endocytosis

0.59	GO:0016301	kinase activity
0.43	GO:0071889	14-3-3 protein binding
0.40	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.37	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0008430	selenium binding

0.44	GO:0005622	intracellular
0.41	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.41	GO:0098805	whole membrane
0.41	GO:0098588	bounding membrane of organelle
0.39	GO:0019867	outer membrane
0.38	GO:0031975	envelope
0.33	GO:0031982	vesicle
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.40

GO:0016773

tr|T1G2I1|T1G2I1_HELRO
Uncharacterized protein
Search

tr|T1G2I2|T1G2I2_HELRO
Uncharacterized protein
Search

0.36	Carbonic anhydrase

0.60	GO:0006730	one-carbon metabolic process
0.57	GO:0036269	swimming behavior
0.38	GO:0015701	bicarbonate transport

0.68	GO:0004089	carbonate dehydratase activity
0.53	GO:0008270	zinc ion binding

0.41	GO:0031225	anchored component of membrane
0.38	GO:0031233	intrinsic component of external side of plasma membrane
0.38	GO:0031526	brush border membrane
0.38	GO:0030667	secretory granule membrane
0.38	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.37	GO:0005791	rough endoplasmic reticulum
0.37	GO:0016324	apical plasma membrane
0.37	GO:0070062	extracellular exosome
0.37	GO:0005802	trans-Golgi network
0.37	GO:0048471	perinuclear region of cytoplasm

0.68

GO:0004089

tr|T1G2I3|T1G2I3_HELRO
Uncharacterized protein
Search

SIX1

0.91	SIX homeobox 1

0.64	GO:0008283	cell proliferation
0.62	GO:0006915	apoptotic process
0.61	GO:0048513	animal organ development
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0090189	regulation of branching involved in ureteric bud morphogenesis
0.54	GO:0072107	positive regulation of ureteric bud formation
0.54	GO:2000729	positive regulation of mesenchymal cell proliferation involved in ureter development
0.54	GO:0071699	olfactory placode morphogenesis

0.65	GO:0043565	sequence-specific DNA binding
0.52	GO:0003700	DNA binding transcription factor activity
0.50	GO:0001012	RNA polymerase II regulatory region DNA binding
0.48	GO:0003682	chromatin binding
0.47	GO:0003690	double-stranded DNA binding
0.41	GO:0008134	transcription factor binding
0.37	GO:0032403	protein complex binding

0.61	GO:0005634	nucleus
0.47	GO:0005667	transcription factor complex
0.44	GO:0070013	intracellular organelle lumen
0.41	GO:0043232	intracellular non-membrane-bounded organelle
0.40	GO:0044446	intracellular organelle part
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|T1G2I4|T1G2I4_HELRO
Uncharacterized protein
Search

0.61	Serine/threonine protein phosphatase 2A regulatory subunit

0.79	GO:0043666	regulation of phosphoprotein phosphatase activity
0.61	GO:0007165	signal transduction
0.42	GO:0045880	positive regulation of smoothened signaling pathway
0.41	GO:0008340	determination of adult lifespan
0.41	GO:0051225	spindle assembly
0.40	GO:0006914	autophagy
0.39	GO:0001933	negative regulation of protein phosphorylation
0.39	GO:0007059	chromosome segregation
0.34	GO:0007623	circadian rhythm

0.80	GO:0019888	protein phosphatase regulator activity
0.34	GO:0005515	protein binding

0.81	GO:0000159	protein phosphatase type 2A complex
0.39	GO:0005829	cytosol
0.33	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1G2I5|T1G2I5_HELRO
Uncharacterized protein
Search

0.71	26S protease regulatory subunit

0.80	GO:1901800	positive regulation of proteasomal protein catabolic process
0.70	GO:0030163	protein catabolic process
0.49	GO:0006508	proteolysis
0.43	GO:0043632	modification-dependent macromolecule catabolic process
0.41	GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly
0.40	GO:0034976	response to endoplasmic reticulum stress
0.39	GO:0010243	response to organonitrogen compound
0.38	GO:0006378	mRNA polyadenylation
0.38	GO:0044267	cellular protein metabolic process
0.38	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

0.81	GO:0036402	proteasome-activating ATPase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.48	GO:0008233	peptidase activity
0.43	GO:0031531	thyrotropin-releasing hormone receptor binding
0.41	GO:0008134	transcription factor binding
0.38	GO:0003729	mRNA binding
0.37	GO:0044877	macromolecular complex binding

0.50	GO:1905369	endopeptidase complex
0.49	GO:0005737	cytoplasm
0.45	GO:0043234	protein complex
0.42	GO:0005634	nucleus
0.41	GO:0070013	intracellular organelle lumen
0.38	GO:0044446	intracellular organelle part
0.38	GO:0097708	intracellular vesicle
0.38	GO:0030687	preribosome, large subunit precursor
0.35	GO:0043232	intracellular non-membrane-bounded organelle
0.35	GO:0072562	blood microparticle

0.48

GO:0008233

tr|T1G2I6|T1G2I6_HELRO
Uncharacterized protein
Search

0.86	Oligodendrocyte transcription factor (Fragment)

0.58	GO:0045165	cell fate commitment
0.56	GO:0048699	generation of neurons
0.56	GO:0007417	central nervous system development
0.55	GO:0006357	regulation of transcription by RNA polymerase II
0.51	GO:0010001	glial cell differentiation
0.48	GO:0048513	animal organ development
0.45	GO:0061074	regulation of neural retina development
0.45	GO:0048384	retinoic acid receptor signaling pathway
0.44	GO:0045893	positive regulation of transcription, DNA-templated
0.44	GO:0009888	tissue development

0.68	GO:0046983	protein dimerization activity
0.47	GO:0003677	DNA binding
0.45	GO:0001067	regulatory region nucleic acid binding
0.43	GO:0003700	DNA binding transcription factor activity
0.41	GO:0003682	chromatin binding
0.34	GO:0052856	NADHX epimerase activity
0.33	GO:0004534	5'-3' exoribonuclease activity
0.33	GO:0004930	G-protein coupled receptor activity
0.32	GO:1901265	nucleoside phosphate binding
0.32	GO:0036094	small molecule binding

0.45	GO:0005667	transcription factor complex
0.37	GO:0005634	nucleus
0.33	GO:0044446	intracellular organelle part
0.33	GO:0005737	cytoplasm
0.33	GO:0043233	organelle lumen
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:5.1

GO:0052856

tr|T1G2I7|T1G2I7_HELRO
Uncharacterized protein
Search

0.38	Prolyl-tRNA synthetase

0.78	GO:0006433	prolyl-tRNA aminoacylation
0.52	GO:0106074	aminoacyl-tRNA metabolism involved in translational fidelity
0.35	GO:0032543	mitochondrial translation
0.34	GO:0046856	phosphatidylinositol dephosphorylation

0.78	GO:0004827	proline-tRNA ligase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0002161	aminoacyl-tRNA editing activity
0.33	GO:0042578	phosphoric ester hydrolase activity

0.49	GO:0005737	cytoplasm
0.33	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016020	membrane

0.78

EC:6.1.1.15

GO:0004827

tr|T1G2I8|T1G2I8_HELRO
Uncharacterized protein
Search

0.67	Vesicle transport through interaction with t-SNAREs homolog 1A

0.69	GO:0006886	intracellular protein transport
0.68	GO:0016192	vesicle-mediated transport
0.56	GO:0061025	membrane fusion
0.42	GO:0072666	establishment of protein localization to vacuole
0.41	GO:0048284	organelle fusion
0.41	GO:0016482	cytosolic transport
0.41	GO:0016050	vesicle organization
0.41	GO:0007034	vacuolar transport
0.41	GO:0016197	endosomal transport

0.65	GO:0005484	SNAP receptor activity
0.42	GO:0000149	SNARE binding
0.33	GO:0008270	zinc ion binding

0.58	GO:0005794	Golgi apparatus
0.42	GO:0031902	late endosome membrane
0.42	GO:0031201	SNARE complex
0.41	GO:0012507	ER to Golgi transport vesicle membrane
0.39	GO:0005789	endoplasmic reticulum membrane
0.39	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

tr|T1G2I9|T1G2I9_HELRO
Uncharacterized protein
Search

tr|T1G2J0|T1G2J0_HELRO
Uncharacterized protein
Search

0.10	Snail homolog 2 (Fragment)

0.54	GO:0000122	negative regulation of transcription by RNA polymerase II
0.53	GO:0035921	desmosome disassembly
0.52	GO:0070563	negative regulation of vitamin D receptor signaling pathway
0.51	GO:0010957	negative regulation of vitamin D biosynthetic process
0.51	GO:0045596	negative regulation of cell differentiation
0.51	GO:0035414	negative regulation of catenin import into nucleus
0.51	GO:0010839	negative regulation of keratinocyte proliferation
0.51	GO:2000810	regulation of bicellular tight junction assembly
0.51	GO:2000811	negative regulation of anoikis
0.51	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator

0.57	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.55	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.51	GO:0003676	nucleic acid binding
0.42	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.40	GO:0005507	copper ion binding
0.40	GO:0003682	chromatin binding

0.46	GO:0005634	nucleus
0.45	GO:0000785	chromatin
0.43	GO:0070013	intracellular organelle lumen
0.42	GO:0005667	transcription factor complex
0.34	GO:0005737	cytoplasm

tr|T1G2J1|T1G2J1_HELRO
Uncharacterized protein
Search

tr|T1G2J2|T1G2J2_HELRO
Uncharacterized protein
Search

0.44	GO:1903506	regulation of nucleic acid-templated transcription
0.44	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.44	GO:0010468	regulation of gene expression
0.42	GO:0040034	regulation of development, heterochronic
0.40	GO:0070895	negative regulation of transposon integration
0.37	GO:1902679	negative regulation of RNA biosynthetic process
0.35	GO:0006351	transcription, DNA-templated
0.32	GO:0055085	transmembrane transport

0.51	GO:0003676	nucleic acid binding
0.44	GO:0046872	metal ion binding
0.40	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding

0.42	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|T1G2J3|T1G2J3_HELRO
Uncharacterized protein
Search

0.10	Dehydrogenase/reductase (SDR family) member 9

0.51	GO:0055114	oxidation-reduction process
0.37	GO:0001890	placenta development
0.37	GO:0001701	in utero embryonic development
0.37	GO:0032526	response to retinoic acid
0.35	GO:0034650	cortisol metabolic process
0.35	GO:0033555	multicellular organismal response to stress
0.34	GO:0051412	response to corticosterone
0.34	GO:0046951	ketone body biosynthetic process
0.34	GO:0060612	adipose tissue development
0.34	GO:0060416	response to growth hormone

0.53	GO:0004745	retinol dehydrogenase activity
0.45	GO:0003858	3-hydroxybutyrate dehydrogenase activity
0.40	GO:0047035	testosterone dehydrogenase (NAD+) activity
0.40	GO:0004303	estradiol 17-beta-dehydrogenase activity
0.35	GO:0052588	diacetyl reductase ((S)-acetoin forming) activity
0.35	GO:0008678	2-deoxy-D-gluconate 3-dehydrogenase activity
0.34	GO:0047001	2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase activity
0.33	GO:0005543	phospholipid binding
0.33	GO:0102131	3-oxo-glutaryl-[acp] methyl ester reductase activity
0.33	GO:0102132	3-oxo-pimeloyl-[acp] methyl ester reductase activity

0.45	GO:0031981	nuclear lumen
0.40	GO:0005829	cytosol
0.40	GO:0005739	mitochondrion
0.39	GO:0019866	organelle inner membrane
0.38	GO:0043232	intracellular non-membrane-bounded organelle
0.37	GO:0098576	lumenal side of membrane
0.30	GO:0031224	intrinsic component of membrane

0.53	EC:1.1.1.105	GO:0004745
0.45	KEGG:R01361	GO:0003858

tr|T1G2J4|T1G2J4_HELRO
Uncharacterized protein
Search

0.12	Steroid receptor RNA activator 1 (Fragment)

tr|T1G2J5|T1G2J5_HELRO
Uncharacterized protein
Search

tr|T1G2J6|T1G2J6_HELRO
Uncharacterized protein
Search

0.67	Calcium-binding protein NCS-1

0.47	GO:1905949	negative regulation of calcium ion import across plasma membrane
0.47	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.44	GO:0042327	positive regulation of phosphorylation
0.38	GO:0043085	positive regulation of catalytic activity
0.37	GO:0009966	regulation of signal transduction
0.34	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway
0.34	GO:0016310	phosphorylation

0.70	GO:0005509	calcium ion binding
0.48	GO:0098744	1-phosphatidylinositol 4-kinase activator activity
0.35	GO:0016301	kinase activity
0.33	GO:0003676	nucleic acid binding
0.33	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.38	GO:0000139	Golgi membrane
0.38	GO:0005886	plasma membrane

0.33

GO:0016773

tr|T1G2J7|T1G2J7_HELRO
Uncharacterized protein
Search

tr|T1G2J8|T1G2J8_HELRO
Mothers against decapentaplegic homolog
Search

0.47	Mothers against decapentaplegic homolog

0.77	GO:0007179	transforming growth factor beta receptor signaling pathway
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0006351	transcription, DNA-templated

0.58	GO:0003700	DNA binding transcription factor activity
0.52	GO:0003677	DNA binding
0.36	GO:0042302	structural constituent of cuticle

0.70	GO:0005667	transcription factor complex
0.58	GO:0005634	nucleus
0.46	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|T1G2J9|T1G2J9_HELRO
Uncharacterized protein
Search

tr|T1G2K0|T1G2K0_HELRO
Uncharacterized protein
Search

0.48	GO:0030198	extracellular matrix organization
0.47	GO:0007160	cell-matrix adhesion
0.46	GO:2000721	positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation
0.46	GO:0010694	positive regulation of alkaline phosphatase activity
0.46	GO:0033631	cell-cell adhesion mediated by integrin
0.45	GO:0007275	multicellular organism development
0.45	GO:1903846	positive regulation of cellular response to transforming growth factor beta stimulus
0.45	GO:0045987	positive regulation of smooth muscle contraction
0.45	GO:0097195	pilomotor reflex
0.44	GO:0045669	positive regulation of osteoblast differentiation

0.70	GO:0005509	calcium ion binding
0.49	GO:0005201	extracellular matrix structural constituent
0.44	GO:0005178	integrin binding
0.39	GO:0008061	chitin binding
0.37	GO:0004872	receptor activity
0.35	GO:0004871	signal transducer activity
0.35	GO:0008201	heparin binding
0.35	GO:0030247	polysaccharide binding
0.34	GO:0050436	microfibril binding
0.34	GO:0004447	iodide peroxidase activity

0.51	GO:0031012	extracellular matrix
0.47	GO:0034678	integrin alpha8-beta1 complex
0.46	GO:0030485	smooth muscle contractile fiber
0.42	GO:0005615	extracellular space
0.34	GO:0005927	muscle tendon junction
0.34	GO:1903561	extracellular vesicle
0.33	GO:0005903	brush border
0.33	GO:0016324	apical plasma membrane
0.33	GO:0030139	endocytic vesicle
0.33	GO:0005905	clathrin-coated pit

0.34

EC:1.11.1.8

GO:0004447

tr|T1G2K1|T1G2K1_HELRO
Uncharacterized protein
Search

EXOC1

0.80	Exocyst complex component 1

0.77	GO:0006887	exocytosis
0.41	GO:0050714	positive regulation of protein secretion
0.41	GO:0051601	exocyst localization
0.41	GO:0048015	phosphatidylinositol-mediated signaling
0.40	GO:0006893	Golgi to plasma membrane transport
0.37	GO:0010457	centriole-centriole cohesion
0.37	GO:0007099	centriole replication
0.32	GO:0016241	regulation of macroautophagy
0.32	GO:0015031	protein transport
0.32	GO:0051607	defense response to virus

0.40	GO:0017049	GTP-Rho binding
0.40	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding

0.79	GO:0000145	exocyst
0.43	GO:0098592	cytoplasmic side of apical plasma membrane
0.33	GO:0090543	Flemming body
0.32	GO:0048471	perinuclear region of cytoplasm
0.32	GO:0005829	cytosol

tr|T1G2K2|T1G2K2_HELRO
Uncharacterized protein
Search

0.11	OTU domain-containing protein 7A-like

0.68	GO:0035871	protein K11-linked deubiquitination
0.57	GO:0032717	negative regulation of interleukin-8 production
0.56	GO:0070536	protein K63-linked deubiquitination
0.56	GO:0071108	protein K48-linked deubiquitination
0.56	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling
0.55	GO:0002385	mucosal immune response
0.55	GO:1900181	negative regulation of protein localization to nucleus
0.51	GO:0000122	negative regulation of transcription by RNA polymerase II
0.49	GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process
0.45	GO:0007219	Notch signaling pathway

0.59	GO:0008270	zinc ion binding
0.56	GO:0070530	K63-linked polyubiquitin modification-dependent protein binding
0.55	GO:1990380	Lys48-specific deubiquitinase activity
0.53	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.52	GO:0003677	DNA binding

0.45	GO:0005634	nucleus
0.39	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|T1G2K3|T1G2K3_HELRO
Uncharacterized protein
Search

CYP4B1

0.73	Leukotriene-B(4) omega-hydroxylase 1

0.53	GO:0055114	oxidation-reduction process
0.36	GO:0016539	intein-mediated protein splicing
0.33	GO:0030258	lipid modification
0.33	GO:0006631	fatty acid metabolic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.67	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding

0.33	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

tr|T1G2K4|T1G2K4_HELRO
Uncharacterized protein
Search

0.51	Angiotensin-converting enzyme

0.61	GO:0006508	proteolysis
0.50	GO:0071838	cell proliferation in bone marrow
0.50	GO:1903597	negative regulation of gap junction assembly
0.50	GO:2000170	positive regulation of peptidyl-cysteine S-nitrosylation
0.49	GO:1900086	positive regulation of peptidyl-tyrosine autophosphorylation
0.49	GO:0003084	positive regulation of systemic arterial blood pressure
0.48	GO:1902033	regulation of hematopoietic stem cell proliferation
0.47	GO:0002446	neutrophil mediated immunity
0.47	GO:0061098	positive regulation of protein tyrosine kinase activity
0.46	GO:0032092	positive regulation of protein binding

0.84	GO:0008241	peptidyl-dipeptidase activity
0.72	GO:0004180	carboxypeptidase activity
0.67	GO:0008237	metallopeptidase activity
0.54	GO:0046872	metal ion binding
0.36	GO:0031711	bradykinin receptor binding
0.36	GO:0031434	mitogen-activated protein kinase kinase binding
0.36	GO:0008240	tripeptidyl-peptidase activity
0.36	GO:0051019	mitogen-activated protein kinase binding
0.35	GO:0031404	chloride ion binding
0.34	GO:0016805	dipeptidase activity

0.42	GO:0097223	sperm part
0.40	GO:0030141	secretory granule
0.38	GO:0005886	plasma membrane
0.35	GO:0045178	basal part of cell
0.35	GO:0097729	9+2 motile cilium
0.35	GO:0005903	brush border
0.35	GO:0070062	extracellular exosome
0.35	GO:0005764	lysosome
0.35	GO:0044441	ciliary part
0.34	GO:0009986	cell surface

0.84

EC:3.4.15

GO:0008241

tr|T1G2K5|T1G2K5_HELRO
Uncharacterized protein
Search

0.10	AT rich interactive domain 3B (BRIGHT-like) (Fragment)

0.72	GO:0006338	chromatin remodeling
0.47	GO:0014017	neuroblast fate commitment
0.46	GO:0048085	adult chitin-containing cuticle pigmentation
0.46	GO:0007406	negative regulation of neuroblast proliferation
0.46	GO:0048190	wing disc dorsal/ventral pattern formation
0.46	GO:0008586	imaginal disc-derived wing vein morphogenesis
0.46	GO:0008587	imaginal disc-derived wing margin morphogenesis
0.46	GO:0007379	segment specification
0.46	GO:0007480	imaginal disc-derived leg morphogenesis
0.45	GO:0042058	regulation of epidermal growth factor receptor signaling pathway

0.55	GO:0003677	DNA binding
0.39	GO:0001104	RNA polymerase II transcription cofactor activity
0.36	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.35	GO:0001067	regulatory region nucleic acid binding
0.33	GO:0005515	protein binding

0.71	GO:0070603	SWI/SNF superfamily-type complex
0.39	GO:0016592	mediator complex
0.30	GO:0031224	intrinsic component of membrane

tr|T1G2K6|T1G2K6_HELRO
Uncharacterized protein
Search

IPO9

0.95	Importin-9

0.68	GO:0006886	intracellular protein transport
0.47	GO:0006606	protein import into nucleus
0.34	GO:0050821	protein stabilization
0.33	GO:0042254	ribosome biogenesis

0.78	GO:0008536	Ran GTPase binding
0.50	GO:0008565	protein transporter activity
0.37	GO:0042393	histone binding

0.58	GO:0005634	nucleus
0.43	GO:0005829	cytosol
0.43	GO:0012505	endomembrane system
0.41	GO:0031967	organelle envelope
0.30	GO:0031224	intrinsic component of membrane

tr|T1G2K7|T1G2K7_HELRO
Uncharacterized protein
Search

WDR26

0.61	LOW QUALITY PROTEIN: WD repeat-containing protein 26

0.32

GO:0008654

phospholipid biosynthetic process

0.39	GO:0005515	protein binding
0.33	GO:0016780	phosphotransferase activity, for other substituted phosphate groups

0.67	GO:0005654	nucleoplasm
0.66	GO:0005829	cytosol
0.43	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:2.7.8

GO:0016780

tr|T1G2K8|T1G2K8_HELRO
Uncharacterized protein
Search

ECSIT

0.93	Intermediate in Toll signal transduction pathway

0.74	GO:0045087	innate immune response
0.45	GO:0051341	regulation of oxidoreductase activity
0.37	GO:0055114	oxidation-reduction process

0.40	GO:0016651	oxidoreductase activity, acting on NAD(P)H
0.39	GO:0005515	protein binding

0.39	GO:0005634	nucleus
0.39	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.40

EC:1.6

GO:0016651

tr|T1G2K9|T1G2K9_HELRO
Uncharacterized protein
Search

NEK4

0.52	Serine/threonine-protein kinase Nek4 isoform 1 (Fragment)

0.63	GO:0006468	protein phosphorylation
0.43	GO:1900062	regulation of replicative cell aging
0.42	GO:2000772	regulation of cellular senescence
0.42	GO:0031098	stress-activated protein kinase signaling cascade
0.41	GO:0032147	activation of protein kinase activity
0.40	GO:2001020	regulation of response to DNA damage stimulus
0.40	GO:0007346	regulation of mitotic cell cycle
0.40	GO:0000278	mitotic cell cycle
0.40	GO:0042981	regulation of apoptotic process
0.39	GO:0045893	positive regulation of transcription, DNA-templated

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0030145	manganese ion binding
0.35	GO:0016757	transferase activity, transferring glycosyl groups

0.39	GO:0005929	cilium
0.38	GO:0005829	cytosol
0.37	GO:0032838	plasma membrane bounded cell projection cytoplasm
0.36	GO:0005815	microtubule organizing center
0.30	GO:0016020	membrane

0.35

GO:0016757

tr|T1G2L0|T1G2L0_HELRO
Uncharacterized protein
Search

LAB

0.95	Labial homeobox protein (Fragment)

0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.48	GO:0048706	embryonic skeletal system development
0.46	GO:0007399	nervous system development
0.45	GO:0060876	semicircular canal formation
0.45	GO:0007600	sensory perception
0.45	GO:0042473	outer ear morphogenesis
0.45	GO:0007634	optokinetic behavior
0.44	GO:0090103	cochlea morphogenesis

0.64	GO:0043565	sequence-specific DNA binding
0.41	GO:0042802	identical protein binding
0.34	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.34	GO:0004000	adenosine deaminase activity

0.61	GO:0005634	nucleus
0.40	GO:0031974	membrane-enclosed lumen
0.37	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.34

EC:3.5.4.4

GO:0004000

tr|T1G2L1|T1G2L1_HELRO
Uncharacterized protein
Search

0.78	GO:0051260	protein homooligomerization
0.47	GO:0002121	inter-male aggressive behavior
0.46	GO:0008343	adult feeding behavior
0.46	GO:0008049	male courtship behavior
0.45	GO:0008344	adult locomotory behavior
0.38	GO:0045892	negative regulation of transcription, DNA-templated
0.33	GO:0051607	defense response to virus
0.33	GO:0007275	multicellular organism development
0.32	GO:0006508	proteolysis
0.32	GO:0006351	transcription, DNA-templated

0.40	GO:0003714	transcription corepressor activity
0.39	GO:0042802	identical protein binding
0.39	GO:0008134	transcription factor binding
0.34	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.33	GO:0004252	serine-type endopeptidase activity
0.32	GO:0004871	signal transducer activity

0.36	GO:0005634	nucleus
0.32	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.34

GO:0004114

tr|T1G2L2|T1G2L2_HELRO
Uncharacterized protein
Search

0.55	Homeodomain transcription factor

0.65	GO:0007275	multicellular organism development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.37	GO:0034101	erythrocyte homeostasis
0.35	GO:0009653	anatomical structure morphogenesis
0.33	GO:0006351	transcription, DNA-templated

0.64	GO:0043565	sequence-specific DNA binding
0.57	GO:0003700	DNA binding transcription factor activity
0.35	GO:0004000	adenosine deaminase activity

0.61

GO:0005634

nucleus

0.35

EC:3.5.4.4

GO:0004000

tr|T1G2L3|T1G2L3_HELRO
Uncharacterized protein
Search

0.11	neuronal acetylcholine receptor subunit alpha-10-like

0.61	GO:0007165	signal transduction
0.60	GO:0034220	ion transmembrane transport
0.46	GO:0060078	regulation of postsynaptic membrane potential
0.45	GO:0098916	anterograde trans-synaptic signaling

0.75	GO:0005230	extracellular ligand-gated ion channel activity
0.70	GO:0099600	transmembrane receptor activity
0.65	GO:0038023	signaling receptor activity
0.44	GO:0140135	mechanosensitive cation channel activity

0.46	GO:0045211	postsynaptic membrane
0.42	GO:0030054	cell junction
0.30	GO:0031224	intrinsic component of membrane

tr|T1G2L4|T1G2L4_HELRO
Uncharacterized protein
Search

NIM1K

0.54	CAMK/CAMKL protein kinase

0.63	GO:0006468	protein phosphorylation
0.50	GO:0030010	establishment of cell polarity
0.47	GO:0000226	microtubule cytoskeleton organization
0.41	GO:0035556	intracellular signal transduction
0.36	GO:0001958	endochondral ossification
0.36	GO:0060351	cartilage development involved in endochondral bone morphogenesis
0.35	GO:0035264	multicellular organism growth
0.35	GO:0035108	limb morphogenesis
0.35	GO:0043066	negative regulation of apoptotic process
0.34	GO:0032880	regulation of protein localization

0.68	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0000287	magnesium ion binding
0.36	GO:0060072	large conductance calcium-activated potassium channel activity
0.33	GO:0005509	calcium ion binding
0.33	GO:0008289	lipid binding
0.33	GO:0005515	protein binding

0.42	GO:0005634	nucleus
0.37	GO:0031974	membrane-enclosed lumen
0.36	GO:0005737	cytoplasm
0.36	GO:0044446	intracellular organelle part
0.33	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.68

GO:0004674

tr|T1G2L5|T1G2L5_HELRO
Uncharacterized protein
Search

GOSR2

0.91	Golgi SNAP receptor complex member 2

0.68	GO:0016192	vesicle-mediated transport
0.67	GO:0061025	membrane fusion
0.55	GO:0015031	protein transport
0.42	GO:0072666	establishment of protein localization to vacuole
0.41	GO:0048284	organelle fusion
0.41	GO:0016482	cytosolic transport
0.41	GO:0016050	vesicle organization
0.41	GO:0007034	vacuolar transport
0.41	GO:0016197	endosomal transport
0.36	GO:0036498	IRE1-mediated unfolded protein response

0.80	GO:0005484	SNAP receptor activity
0.42	GO:0000149	SNARE binding
0.34	GO:0004930	G-protein coupled receptor activity

0.70	GO:0005794	Golgi apparatus
0.42	GO:0031902	late endosome membrane
0.42	GO:0031201	SNARE complex
0.41	GO:0012507	ER to Golgi transport vesicle membrane
0.41	GO:0005789	endoplasmic reticulum membrane
0.39	GO:0005829	cytosol
0.35	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane
0.30	GO:0016021	integral component of membrane

tr|T1G2L6|T1G2L6_HELRO
Uncharacterized protein
Search

0.44	RNA-binding proteins (RRM domain)

0.35

GO:0006402

mRNA catabolic process

0.59

GO:0003723

RNA binding

0.36	GO:0030014	CCR4-NOT complex
0.30	GO:0044425	membrane part

tr|T1G2L7|T1G2L7_HELRO
Uncharacterized protein
Search

0.65	GO:0051569	regulation of histone H3-K4 methylation
0.60	GO:0030097	hemopoiesis
0.49	GO:1903506	regulation of nucleic acid-templated transcription
0.49	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.49	GO:0070105	positive regulation of interleukin-6-mediated signaling pathway
0.48	GO:0010468	regulation of gene expression
0.48	GO:0010956	negative regulation of calcidiol 1-monooxygenase activity
0.46	GO:0034121	regulation of toll-like receptor signaling pathway
0.45	GO:0010977	negative regulation of neuron projection development
0.45	GO:0071222	cellular response to lipopolysaccharide

0.51	GO:0003676	nucleic acid binding
0.47	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.40	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding
0.32	GO:0008168	methyltransferase activity
0.32	GO:0140102	catalytic activity, acting on a rRNA

0.45	GO:0016363	nuclear matrix
0.44	GO:0017053	transcriptional repressor complex
0.44	GO:0016604	nuclear body
0.30	GO:0016020	membrane

0.32

GO:0008168

tr|T1G2L8|T1G2L8_HELRO
Uncharacterized protein
Search

0.39	Peptide chain release factor subunit 3

0.60	GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
0.59	GO:0006415	translational termination
0.45	GO:0006414	translational elongation
0.40	GO:0002181	cytoplasmic translation

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.58	GO:0008079	translation termination factor activity
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0003746	translation elongation factor activity
0.35	GO:0004781	sulfate adenylyltransferase (ATP) activity

0.42	GO:0018444	translation release factor complex
0.39	GO:0005829	cytosol

0.35

EC:2.7.7.4

GO:0004781

tr|T1G2L9|T1G2L9_HELRO
Uncharacterized protein
Search

0.39	Succinate dehydrogenase complex subunit C

0.71	GO:0006099	tricarboxylic acid cycle
0.57	GO:0022900	electron transport chain
0.36	GO:0006119	oxidative phosphorylation

0.77	GO:0000104	succinate dehydrogenase activity
0.58	GO:0009055	electron transfer activity
0.51	GO:0046872	metal ion binding
0.36	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor

0.80	GO:0045281	succinate dehydrogenase complex
0.40	GO:0045283	fumarate reductase complex
0.39	GO:0005746	mitochondrial respiratory chain
0.38	GO:0098800	inner mitochondrial membrane protein complex
0.30	GO:0016021	integral component of membrane

0.77

EC:1.3.99.1

GO:0000104

tr|T1G2M0|T1G2M0_HELRO
Uncharacterized protein
Search

0.48

epsin-1

0.63	GO:1903671	negative regulation of sprouting angiogenesis
0.60	GO:0006897	endocytosis
0.58	GO:0007565	female pregnancy
0.56	GO:0001701	in utero embryonic development
0.56	GO:0007219	Notch signaling pathway
0.55	GO:0048568	embryonic organ development
0.39	GO:1905445	positive regulation of clathrin coat assembly
0.38	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway
0.36	GO:1902358	sulfate transmembrane transport
0.36	GO:0061024	membrane organization

0.40	GO:0008289	lipid binding
0.38	GO:0035615	clathrin adaptor activity
0.38	GO:0044325	ion channel binding
0.37	GO:0008271	secondary active sulfate transmembrane transporter activity
0.36	GO:0008134	transcription factor binding
0.34	GO:0003723	RNA binding

0.68	GO:0030139	endocytic vesicle
0.65	GO:0030125	clathrin vesicle coat
0.53	GO:0005829	cytosol
0.49	GO:0031143	pseudopodium
0.49	GO:0001891	phagocytic cup
0.42	GO:0005905	clathrin-coated pit
0.40	GO:0098890	extrinsic component of postsynaptic membrane
0.40	GO:0098888	extrinsic component of presynaptic membrane
0.39	GO:0005634	nucleus
0.38	GO:0043195	terminal bouton

tr|T1G2M1|T1G2M1_HELRO
Uncharacterized protein
Search

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.41	GO:0048731	system development
0.39	GO:0072137	condensed mesenchymal cell proliferation
0.39	GO:0050808	synapse organization
0.39	GO:0007267	cell-cell signaling
0.39	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.39	GO:0048729	tissue morphogenesis
0.38	GO:0035329	hippo signaling
0.38	GO:0035239	tube morphogenesis
0.38	GO:0060429	epithelium development

0.70	GO:0005509	calcium ion binding
0.35	GO:0050839	cell adhesion molecule binding
0.34	GO:0032403	protein complex binding
0.33	GO:0060089	molecular transducer activity
0.33	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity
0.33	GO:0004022	alcohol dehydrogenase (NAD) activity
0.33	GO:0004867	serine-type endopeptidase inhibitor activity
0.33	GO:0004871	signal transducer activity

0.56	GO:0005886	plasma membrane
0.37	GO:0045177	apical part of cell
0.35	GO:0005912	adherens junction
0.35	GO:0098858	actin-based cell projection
0.35	GO:0031254	cell trailing edge
0.34	GO:0045178	basal part of cell
0.34	GO:0030055	cell-substrate junction
0.33	GO:0005911	cell-cell junction
0.33	GO:0089717	spanning component of membrane
0.33	GO:0005903	brush border

0.33

EC:2.7.11.23

GO:0008353

tr|T1G2M2|T1G2M2_HELRO
Uncharacterized protein
Search

GCLC

0.72	Glutamate--cysteine ligase catalytic subunit

0.79	GO:0006750	glutathione biosynthetic process
0.55	GO:0051900	regulation of mitochondrial depolarization
0.54	GO:0008637	apoptotic mitochondrial changes
0.54	GO:0019852	L-ascorbic acid metabolic process
0.53	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway
0.53	GO:0031397	negative regulation of protein ubiquitination
0.53	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.52	GO:0050880	regulation of blood vessel size
0.52	GO:0046685	response to arsenic-containing substance
0.50	GO:0009410	response to xenobiotic stimulus

0.79	GO:0004357	glutamate-cysteine ligase activity
0.56	GO:0016595	glutamate binding
0.49	GO:0043531	ADP binding
0.49	GO:0046982	protein heterodimerization activity
0.45	GO:0000287	magnesium ion binding
0.43	GO:0050662	coenzyme binding
0.33	GO:0005524	ATP binding
0.33	GO:0003676	nucleic acid binding

0.58	GO:0017109	glutamate-cysteine ligase complex
0.46	GO:0005829	cytosol
0.34	GO:0005921	gap junction
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.79	EC:6.3.2.2	GO:0004357
0.79	KEGG:R00894	GO:0004357

tr|T1G2M3|T1G2M3_HELRO
Uncharacterized protein
Search

SRL

0.91	Putative sarcoplasmic reticulum glycoprotein putative sarcalumenin

0.54	GO:0014873	response to muscle activity involved in regulation of muscle adaptation
0.52	GO:0002115	store-operated calcium entry
0.36	GO:0032456	endocytic recycling
0.34	GO:0030036	actin cytoskeleton organization

0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0005509	calcium ion binding
0.32	GO:0003924	GTPase activity

0.40	GO:0033018	sarcoplasmic reticulum lumen
0.30	GO:0031224	intrinsic component of membrane

tr|T1G2M4|T1G2M4_HELRO
Histone acetyltransferase
Search

KAT7

0.54	Histone acetyltransferase

0.78	GO:0016573	histone acetylation
0.58	GO:0072739	response to anisomycin
0.58	GO:0072720	response to dithiothreitol
0.57	GO:0072708	response to sorbitol
0.57	GO:0006355	regulation of transcription, DNA-templated
0.57	GO:0072716	response to actinomycin D
0.56	GO:0090240	positive regulation of histone H4 acetylation
0.56	GO:0072710	response to hydroxyurea
0.53	GO:1900182	positive regulation of protein localization to nucleus
0.53	GO:0031098	stress-activated protein kinase signaling cascade

0.80	GO:0004402	histone acetyltransferase activity
0.62	GO:0008270	zinc ion binding
0.60	GO:0003700	DNA binding transcription factor activity
0.50	GO:0003688	DNA replication origin binding
0.49	GO:0044212	transcription regulatory region DNA binding
0.43	GO:0003713	transcription coactivator activity
0.41	GO:0008134	transcription factor binding

0.61	GO:0005634	nucleus
0.49	GO:0031248	protein acetyltransferase complex
0.47	GO:0005829	cytosol
0.46	GO:0031974	membrane-enclosed lumen
0.42	GO:0044446	intracellular organelle part
0.34	GO:0043232	intracellular non-membrane-bounded organelle

0.80

GO:0004402

tr|T1G2M5|T1G2M5_HELRO
Uncharacterized protein
Search

0.51	GO:1903506	regulation of nucleic acid-templated transcription
0.51	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.50	GO:0010468	regulation of gene expression
0.37	GO:0045773	positive regulation of axon extension
0.37	GO:0006351	transcription, DNA-templated
0.37	GO:0007411	axon guidance
0.34	GO:1902679	negative regulation of RNA biosynthetic process
0.34	GO:0061321	garland nephrocyte differentiation
0.34	GO:0007516	hemocyte development
0.34	GO:0007280	pole cell migration

0.51	GO:0003676	nucleic acid binding
0.45	GO:0046872	metal ion binding
0.39	GO:0003700	DNA binding transcription factor activity
0.33	GO:0004140	dephospho-CoA kinase activity
0.32	GO:0005515	protein binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.52	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.33	EC:2.7.1.24	GO:0004140
0.33	KEGG:R00130	GO:0004140

tr|T1G2M6|T1G2M6_HELRO
Uncharacterized protein
Search

0.16	WD repeat-containing protein 86 (Fragment)

0.84	GO:0031642	negative regulation of myelination
0.79	GO:0045746	negative regulation of Notch signaling pathway
0.75	GO:0001525	angiogenesis
0.73	GO:1902531	regulation of intracellular signal transduction
0.62	GO:1903223	positive regulation of oxidative stress-induced neuron death
0.61	GO:0045741	positive regulation of epidermal growth factor-activated receptor activity
0.61	GO:0032876	negative regulation of DNA endoreduplication
0.60	GO:2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.59	GO:0043525	positive regulation of neuron apoptotic process
0.59	GO:1903146	regulation of autophagy of mitochondrion

0.62	GO:0050816	phosphothreonine residue binding
0.57	GO:0097027	ubiquitin-protein transferase activator activity
0.56	GO:0030332	cyclin binding
0.55	GO:0030674	protein binding, bridging
0.55	GO:0031625	ubiquitin protein ligase binding
0.52	GO:0042802	identical protein binding

0.62	GO:1990452	Parkin-FBXW7-Cul1 ubiquitin ligase complex
0.57	GO:0019005	SCF ubiquitin ligase complex
0.40	GO:0005737	cytoplasm

tr|T1G2M7|T1G2M7_HELRO
Uncharacterized protein
Search

DHRS11

0.30	NADP-dependent 3-hydroxy acid dehydrogenase YdfG

0.55	GO:0006694	steroid biosynthetic process
0.52	GO:0055114	oxidation-reduction process
0.41	GO:0008210	estrogen metabolic process
0.39	GO:0042446	hormone biosynthetic process
0.36	GO:0046710	GDP metabolic process
0.35	GO:0046037	GMP metabolic process
0.34	GO:0044249	cellular biosynthetic process
0.32	GO:0016310	phosphorylation

0.64	GO:0072555	17-beta-ketosteroid reductase activity
0.64	GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity
0.62	GO:0000253	3-keto sterol reductase activity
0.60	GO:0004303	estradiol 17-beta-dehydrogenase activity
0.37	GO:0102132	3-oxo-pimeloyl-[acp] methyl ester reductase activity
0.37	GO:0102131	3-oxo-glutaryl-[acp] methyl ester reductase activity
0.36	GO:0004316	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
0.36	GO:0004385	guanylate kinase activity
0.34	GO:1901265	nucleoside phosphate binding
0.34	GO:0050038	L-xylulose reductase (NADP+) activity

0.37	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.62	EC:1.1.1.270	GO:0000253
0.34	KEGG:R01904	GO:0050038

tr|T1G2M8|T1G2M8_HELRO
Uncharacterized protein
Search

0.51	GO:0007411	axon guidance
0.50	GO:0006468	protein phosphorylation
0.49	GO:0048583	regulation of response to stimulus
0.49	GO:0023051	regulation of signaling
0.49	GO:0010646	regulation of cell communication
0.48	GO:0007166	cell surface receptor signaling pathway
0.47	GO:0071345	cellular response to cytokine stimulus
0.46	GO:0018212	peptidyl-tyrosine modification
0.46	GO:0065009	regulation of molecular function
0.44	GO:0021772	olfactory bulb development

0.50	GO:0004672	protein kinase activity
0.49	GO:0019955	cytokine binding
0.48	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.48	GO:0004888	transmembrane signaling receptor activity
0.45	GO:0030554	adenyl nucleotide binding
0.44	GO:0097367	carbohydrate derivative binding
0.44	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0008144	drug binding
0.41	GO:0019903	protein phosphatase binding
0.41	GO:0042802	identical protein binding

0.43	GO:1990682	CSF1-CSF1R complex
0.41	GO:0009986	cell surface
0.39	GO:0044459	plasma membrane part
0.38	GO:0044421	extracellular region part
0.38	GO:0044304	main axon
0.37	GO:0031252	cell leading edge
0.37	GO:0005654	nucleoplasm
0.37	GO:0005938	cell cortex
0.36	GO:0030054	cell junction
0.36	GO:0031982	vesicle

0.38

GO:0008233

tr|T1G2M9|T1G2M9_HELRO
Uncharacterized protein
Search

SLC17A9

0.67	Collagen type XX alpha 1 chain

0.55	GO:0055085	transmembrane transport
0.50	GO:1903146	regulation of autophagy of mitochondrion
0.50	GO:1903955	positive regulation of protein targeting to mitochondrion
0.41	GO:0006820	anion transport
0.35	GO:0006887	exocytosis
0.32	GO:0000278	mitotic cell cycle

0.49	GO:0005215	transporter activity
0.32	GO:0046872	metal ion binding

0.32	GO:0009536	plastid
0.32	GO:0000775	chromosome, centromeric region
0.32	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|T1G2N0|T1G2N0_HELRO
Uncharacterized protein
Search

ADCK5

0.90	AarF domain-containing protein kinase

0.54	GO:0016310	phosphorylation
0.37	GO:0036211	protein modification process
0.36	GO:0044267	cellular protein metabolic process
0.36	GO:0090382	phagosome maturation
0.35	GO:0006895	Golgi to endosome transport
0.35	GO:0032456	endocytic recycling
0.35	GO:0042742	defense response to bacterium
0.33	GO:0055114	oxidation-reduction process

0.56	GO:0016301	kinase activity
0.37	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.36	GO:0140096	catalytic activity, acting on a protein
0.35	GO:0032555	purine ribonucleotide binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.35	GO:0004497	monooxygenase activity
0.35	GO:0030554	adenyl nucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0020037	heme binding

0.35	GO:0005739	mitochondrion
0.35	GO:0045335	phagocytic vesicle
0.35	GO:0055037	recycling endosome
0.35	GO:0005802	trans-Golgi network
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.37

GO:0016773

tr|T1G2N1|T1G2N1_HELRO
Uncharacterized protein
Search

TMEM33

0.97	Transmembrane protein 33

0.56	GO:1903896	positive regulation of IRE1-mediated unfolded protein response
0.55	GO:1903899	positive regulation of PERK-mediated unfolded protein response
0.55	GO:1903371	regulation of endoplasmic reticulum tubular network organization
0.50	GO:0034976	response to endoplasmic reticulum stress
0.50	GO:0051292	nuclear pore complex assembly
0.50	GO:0071786	endoplasmic reticulum tubular network organization
0.43	GO:0034613	cellular protein localization
0.33	GO:0007186	G-protein coupled receptor signaling pathway

0.47	GO:0017056	structural constituent of nuclear pore
0.34	GO:0005515	protein binding
0.33	GO:0004930	G-protein coupled receptor activity

0.52	GO:0042470	melanosome
0.51	GO:0005635	nuclear envelope
0.49	GO:0030176	integral component of endoplasmic reticulum membrane
0.40	GO:0043234	protein complex
0.35	GO:0070062	extracellular exosome

tr|T1G2N2|T1G2N2_HELRO
DNA replication complex GINS protein PSF2
Search

GINS2

0.75	DNA replication complex GINS protein PSF2

0.65	GO:0006260	DNA replication
0.49	GO:0000727	double-strand break repair via break-induced replication
0.46	GO:1903047	mitotic cell cycle process
0.44	GO:0032392	DNA geometric change
0.36	GO:0022616	DNA strand elongation
0.34	GO:0032784	regulation of DNA-templated transcription, elongation

0.47	GO:0043138	3'-5' DNA helicase activity
0.34	GO:0003682	chromatin binding
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.45	GO:0005657	replication fork
0.45	GO:0032993	protein-DNA complex
0.43	GO:0031974	membrane-enclosed lumen
0.40	GO:0043234	protein complex
0.30	GO:0016020	membrane

tr|T1G2N3|T1G2N3_HELRO
Uncharacterized protein
Search

0.51	Dolichol kinase (Fragment)

0.84	GO:0043048	dolichyl monophosphate biosynthetic process
0.57	GO:0016310	phosphorylation
0.44	GO:0006486	protein glycosylation
0.35	GO:0000724	double-strand break repair via homologous recombination
0.34	GO:0051276	chromosome organization

0.84	GO:0004168	dolichol kinase activity
0.36	GO:0016779	nucleotidyltransferase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.46	GO:0030176	integral component of endoplasmic reticulum membrane
0.35	GO:0030915	Smc5-Smc6 complex

0.84

EC:2.7.1.108

GO:0004168

tr|T1G2N4|T1G2N4_HELRO
Uncharacterized protein
Search

0.10	PDZ domain-containing RING finger protein 3

0.51	GO:0007528	neuromuscular junction development
0.47	GO:0016567	protein ubiquitination
0.36	GO:0022904	respiratory electron transport chain

0.59	GO:0016874	ligase activity
0.48	GO:0061630	ubiquitin protein ligase activity
0.42	GO:0008270	zinc ion binding
0.36	GO:0005515	protein binding

0.51	GO:0031594	neuromuscular junction
0.44	GO:0005654	nucleoplasm
0.43	GO:0005829	cytosol
0.41	GO:0030054	cell junction
0.36	GO:0005882	intermediate filament
0.30	GO:0044425	membrane part

0.59

GO:0016874

tr|T1G2N5|T1G2N5_HELRO
Uncharacterized protein
Search

UBE2F

0.74	Putative ubiquitin-conjugating enzyme

0.49	GO:0045116	protein neddylation
0.44	GO:0016567	protein ubiquitination
0.34	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.34	GO:0043687	post-translational protein modification
0.33	GO:0006886	intracellular protein transport

0.54	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0019788	NEDD8 transferase activity
0.46	GO:0031625	ubiquitin protein ligase binding
0.45	GO:0061630	ubiquitin protein ligase activity
0.37	GO:0016874	ligase activity
0.33	GO:0008565	protein transporter activity

0.36	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.37

GO:0016874

tr|T1G2N6|T1G2N6_HELRO
Uncharacterized protein
Search

0.79	Leukotriene-B(4) omega-hydroxylase 1

0.53	GO:0055114	oxidation-reduction process
0.36	GO:0016539	intein-mediated protein splicing
0.33	GO:0030258	lipid modification
0.33	GO:0006631	fatty acid metabolic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.66	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding

0.33	GO:0005789	endoplasmic reticulum membrane
0.32	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

tr|T1G2N7|T1G2N7_HELRO
Uncharacterized protein
Search

0.58	Glutamate receptor 1

0.78	GO:0060079	excitatory postsynaptic potential
0.77	GO:0035235	ionotropic glutamate receptor signaling pathway
0.58	GO:0006811	ion transport
0.51	GO:0055085	transmembrane transport
0.38	GO:0099566	regulation of postsynaptic cytosolic calcium ion concentration
0.38	GO:0050805	negative regulation of synaptic transmission
0.38	GO:0048167	regulation of synaptic plasticity
0.37	GO:0031623	receptor internalization
0.37	GO:0007616	long-term memory
0.34	GO:0050806	positive regulation of synaptic transmission

0.80	GO:0005234	extracellularly glutamate-gated ion channel activity
0.77	GO:0004970	ionotropic glutamate receptor activity
0.43	GO:0099094	ligand-gated cation channel activity
0.38	GO:0099583	neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration
0.37	GO:1904315	transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential
0.35	GO:0005272	sodium channel activity
0.35	GO:0098782	mechanosensitived potassium channel activity
0.32	GO:0003676	nucleic acid binding

0.76	GO:0045211	postsynaptic membrane
0.71	GO:0030054	cell junction
0.45	GO:0032281	AMPA glutamate receptor complex
0.40	GO:0043025	neuronal cell body
0.39	GO:0030425	dendrite
0.38	GO:0044308	axonal spine
0.38	GO:0014069	postsynaptic density
0.37	GO:0032589	neuron projection membrane
0.37	GO:0098793	presynapse
0.37	GO:0070382	exocytic vesicle

tr|T1G2N8|T1G2N8_HELRO
Uncharacterized protein
Search

0.63	Pre-mRNA processing factor 4B

0.63	GO:0006468	protein phosphorylation
0.37	GO:0008380	RNA splicing
0.37	GO:0006397	mRNA processing

0.64	GO:0004672	protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0060089	molecular transducer activity
0.33	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.51	GO:0071013	catalytic step 2 spliceosome
0.50	GO:0016607	nuclear speck
0.45	GO:0005694	chromosome
0.30	GO:0031224	intrinsic component of membrane

tr|T1G2N9|T1G2N9_HELRO
Uncharacterized protein
Search

ALKBH7

0.96	Alpha-ketoglutarate-dependent dioxygenase alkB, mitochondrial

0.86	GO:1902445	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death
0.65	GO:0006974	cellular response to DNA damage stimulus
0.47	GO:0010883	regulation of lipid storage
0.42	GO:0006631	fatty acid metabolic process
0.42	GO:0055114	oxidation-reduction process
0.37	GO:0006333	chromatin assembly or disassembly
0.35	GO:0043043	peptide biosynthetic process
0.34	GO:0044267	cellular protein metabolic process
0.34	GO:0010467	gene expression
0.34	GO:0009059	macromolecule biosynthetic process

0.50	GO:0051213	dioxygenase activity
0.35	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.33	GO:0046872	metal ion binding

0.75	GO:0005759	mitochondrial matrix
0.34	GO:0005634	nucleus

0.35

GO:0016705

tr|T1G2P0|T1G2P0_HELRO
Uncharacterized protein
Search

HNRNPR

0.69	Heterogeneous nuclear ribonucleoprotein R

0.60	GO:0016554	cytidine to uridine editing
0.40	GO:0002244	hematopoietic progenitor cell differentiation
0.40	GO:2000742	regulation of anterior head development
0.38	GO:0016556	mRNA modification
0.38	GO:0060322	head development
0.37	GO:0061157	mRNA destabilization
0.37	GO:0007623	circadian rhythm
0.35	GO:1902284	neuron projection extension involved in neuron projection guidance
0.35	GO:0043086	negative regulation of catalytic activity
0.35	GO:0048675	axon extension

0.59	GO:0003723	RNA binding
0.33	GO:0004842	ubiquitin-protein transferase activity
0.32	GO:0005515	protein binding
0.32	GO:0046872	metal ion binding

0.49	GO:0019013	viral nucleocapsid
0.47	GO:0030529	intracellular ribonucleoprotein complex
0.42	GO:0005654	nucleoplasm
0.40	GO:1902494	catalytic complex
0.39	GO:0030895	apolipoprotein B mRNA editing enzyme complex
0.37	GO:0043679	axon terminus
0.37	GO:0030426	growth cone
0.36	GO:0030425	dendrite
0.35	GO:0005730	nucleolus
0.33	GO:0005737	cytoplasm

0.33

GO:0004842

tr|T1G2P1|T1G2P1_HELRO
Uncharacterized protein
Search

ALG10

0.90	Asparagine-linked glycosylation 10

0.83	GO:0006488	dolichol-linked oligosaccharide biosynthetic process
0.50	GO:0060117	auditory receptor cell development
0.48	GO:0007605	sensory perception of sound
0.38	GO:0043413	macromolecule glycosylation
0.38	GO:0009101	glycoprotein biosynthetic process
0.38	GO:1901980	positive regulation of inward rectifier potassium channel activity
0.37	GO:0048366	leaf development
0.37	GO:0009651	response to salt stress
0.37	GO:0060050	positive regulation of protein glycosylation
0.36	GO:0036211	protein modification process

0.85	GO:0004583	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity
0.42	GO:0106073	dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity
0.36	GO:0015459	potassium channel regulator activity
0.32	GO:0003964	RNA-directed DNA polymerase activity

0.72	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.85

GO:0004583

tr|T1G2P2|T1G2P2_HELRO
Uncharacterized protein
Search

0.53	Mitogen-activated protein kinase kinase kinase 13

0.81	GO:0000186	activation of MAPKK activity
0.78	GO:0046777	protein autophosphorylation
0.77	GO:0000165	MAPK cascade
0.64	GO:0031098	stress-activated protein kinase signaling cascade
0.53	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.48	GO:2000672	negative regulation of motor neuron apoptotic process
0.46	GO:0016572	histone phosphorylation
0.46	GO:0048674	collateral sprouting of injured axon
0.46	GO:0018107	peptidyl-threonine phosphorylation
0.45	GO:0018105	peptidyl-serine phosphorylation

0.82	GO:0004709	MAP kinase kinase kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0042803	protein homodimerization activity
0.44	GO:0019901	protein kinase binding
0.39	GO:0046872	metal ion binding

0.50	GO:0008385	IkappaB kinase complex
0.49	GO:0030424	axon
0.46	GO:0030426	growth cone
0.38	GO:0005886	plasma membrane

0.82

EC:2.7.11 EC:2.7.11.25

GO:0004709

tr|T1G2P3|T1G2P3_HELRO
Uncharacterized protein
Search

0.22	S-adenosyl-L-methionine-dependent methyltransferase

0.73	GO:0008213	protein alkylation
0.67	GO:0043414	macromolecule methylation
0.46	GO:0018195	peptidyl-arginine modification
0.44	GO:0016570	histone modification
0.35	GO:1903506	regulation of nucleic acid-templated transcription
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression
0.33	GO:0016310	phosphorylation

0.63	GO:0008168	methyltransferase activity
0.39	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0005515	protein binding
0.33	GO:0016301	kinase activity

0.39	GO:0005634	nucleus
0.37	GO:0005829	cytosol
0.33	GO:0005840	ribosome

0.63

GO:0008168

tr|T1G2P4|T1G2P4_HELRO
Phosphodiesterase
Search

0.48	Camp-specific 3-cyclic phosphodiesterase

0.61	GO:0007165	signal transduction
0.35	GO:0006546	glycine catabolic process
0.33	GO:0055114	oxidation-reduction process

0.80	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.54	GO:0046872	metal ion binding
0.35	GO:0016642	oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor

0.80

GO:0004114

tr|T1G2P5|T1G2P5_HELRO
Uncharacterized protein
Search

tr|T1G2P6|T1G2P6_HELRO
Uncharacterized protein
Search

0.61	Calcium-independent phospholipase A2-gamma

0.71	GO:0016042	lipid catabolic process
0.53	GO:0043651	linoleic acid metabolic process
0.51	GO:0046457	prostanoid biosynthetic process
0.51	GO:0019369	arachidonic acid metabolic process
0.51	GO:0006693	prostaglandin metabolic process
0.49	GO:0046470	phosphatidylcholine metabolic process
0.49	GO:1903963	arachidonate transport
0.49	GO:0032309	icosanoid secretion
0.48	GO:0046337	phosphatidylethanolamine metabolic process
0.47	GO:0008219	cell death

0.53	GO:0047499	calcium-independent phospholipase A2 activity
0.36	GO:0004622	lysophospholipase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.48	GO:0031903	microbody membrane
0.48	GO:0044439	peroxisomal part
0.35	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0000139	Golgi membrane
0.35	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

0.36

EC:3.1.1.5

GO:0004622

tr|T1G2P7|T1G2P7_HELRO
Uncharacterized protein
Search

tr|T1G2P8|T1G2P8_HELRO
Uncharacterized protein
Search

0.66	Ultrabithorax

0.61	GO:0007275	multicellular organism development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.45	GO:0006366	transcription by RNA polymerase II
0.44	GO:1902680	positive regulation of RNA biosynthetic process
0.43	GO:0008354	germ cell migration
0.42	GO:0009888	tissue development
0.42	GO:0009653	anatomical structure morphogenesis
0.42	GO:1902679	negative regulation of RNA biosynthetic process

0.64	GO:0043565	sequence-specific DNA binding
0.55	GO:0003700	DNA binding transcription factor activity
0.45	GO:0001012	RNA polymerase II regulatory region DNA binding
0.43	GO:0003690	double-stranded DNA binding
0.43	GO:0035326	enhancer binding
0.34	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.33	GO:0071837	HMG box domain binding

0.61	GO:0005634	nucleus
0.41	GO:0031974	membrane-enclosed lumen
0.40	GO:0030054	cell junction
0.38	GO:0044446	intracellular organelle part
0.32	GO:0005829	cytosol
0.32	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

0.34

GO:0003950

tr|T1G2P9|T1G2P9_HELRO
Polypeptide N-acetylgalactosaminyltransferase
Search

0.62	Polypeptide N-acetylgalactosaminyltransferase

0.71	GO:0006486	protein glycosylation
0.45	GO:0007049	cell cycle
0.43	GO:0018210	peptidyl-threonine modification
0.41	GO:0006351	transcription, DNA-templated
0.41	GO:0018209	peptidyl-serine modification
0.33	GO:0006298	mismatch repair
0.31	GO:0006508	proteolysis

0.67	GO:0030246	carbohydrate binding
0.63	GO:0016757	transferase activity, transferring glycosyl groups
0.39	GO:0030145	manganese ion binding
0.37	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0030983	mismatched DNA binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.31	GO:0017171	serine hydrolase activity

0.70	GO:0000139	Golgi membrane
0.54	GO:0070176	DRM complex
0.40	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0031985	Golgi cisterna
0.34	GO:0005576	extracellular region
0.34	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.63

GO:0016757

tr|T1G2Q0|T1G2Q0_HELRO
Uncharacterized protein
Search

tr|T1G2Q1|T1G2Q1_HELRO
Uncharacterized protein
Search

0.43	Na-K-Cl cotransporter

0.55	GO:0055085	transmembrane transport
0.43	GO:0006821	chloride transport
0.41	GO:0071804	cellular potassium ion transport
0.34	GO:0006865	amino acid transport
0.34	GO:0060271	cilium assembly
0.33	GO:0006886	intracellular protein transport
0.33	GO:0016192	vesicle-mediated transport
0.33	GO:0007043	cell-cell junction assembly
0.33	GO:0007507	heart development
0.32	GO:0007268	chemical synaptic transmission

0.45	GO:0015379	potassium:chloride symporter activity
0.43	GO:0022820	potassium ion symporter activity
0.35	GO:0015171	amino acid transmembrane transporter activity
0.34	GO:0005247	voltage-gated chloride channel activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0005509	calcium ion binding

0.34	GO:0048475	coated membrane
0.33	GO:0098796	membrane protein complex
0.32	GO:0044444	cytoplasmic part
0.30	GO:0016021	integral component of membrane

tr|T1G2Q2|T1G2Q2_HELRO
Uncharacterized protein
Search

ORC5

0.90	Origin recognition complex subunit 5

0.66	GO:0006260	DNA replication
0.35	GO:0000082	G1/S transition of mitotic cell cycle
0.34	GO:0000055	ribosomal large subunit export from nucleus
0.33	GO:0042273	ribosomal large subunit biogenesis
0.33	GO:0030036	actin cytoskeleton organization
0.33	GO:0031938	regulation of chromatin silencing at telomere
0.33	GO:0030466	chromatin silencing at silent mating-type cassette
0.32	GO:0065004	protein-DNA complex assembly
0.32	GO:0019441	tryptophan catabolic process to kynurenine

0.47	GO:0003688	DNA replication origin binding
0.34	GO:0005515	protein binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0004061	arylformamidase activity

0.82	GO:0000808	origin recognition complex
0.61	GO:0005634	nucleus
0.49	GO:0031974	membrane-enclosed lumen
0.48	GO:0005829	cytosol
0.37	GO:0000781	chromosome, telomeric region
0.33	GO:0036387	pre-replicative complex
0.30	GO:0016020	membrane

0.32

EC:3.5.1.9

GO:0004061

tr|T1G2Q3|T1G2Q3_HELRO
Uncharacterized protein
Search

0.64	GO:0051270	regulation of cellular component movement
0.63	GO:0040012	regulation of locomotion
0.62	GO:0045995	regulation of embryonic development
0.59	GO:0007155	cell adhesion
0.58	GO:0030155	regulation of cell adhesion
0.53	GO:0003143	embryonic heart tube morphogenesis
0.52	GO:0097155	fasciculation of sensory neuron axon
0.52	GO:0060971	embryonic heart tube left/right pattern formation
0.51	GO:0071907	determination of digestive tract left/right asymmetry
0.50	GO:0045773	positive regulation of axon extension

0.56	GO:0005102	receptor binding
0.51	GO:0005509	calcium ion binding
0.48	GO:0008022	protein C-terminus binding
0.36	GO:0005044	scavenger receptor activity
0.36	GO:0004672	protein kinase activity
0.35	GO:0030554	adenyl nucleotide binding
0.34	GO:0097367	carbohydrate derivative binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0001849	complement component C1q binding

0.55	GO:0005605	basal lamina
0.46	GO:0005615	extracellular space
0.41	GO:0005634	nucleus
0.40	GO:0043234	protein complex
0.34	GO:1903561	extracellular vesicle
0.34	GO:0042383	sarcolemma
0.34	GO:0001891	phagocytic cup
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0036459

tr|T1G2Q4|T1G2Q4_HELRO
Uncharacterized protein
Search

tr|T1G2Q5|T1G2Q5_HELRO
Uncharacterized protein
Search

TM2D1

0.50	TM2 domain-containing protein 1

0.50	GO:0097190	apoptotic signaling pathway
0.46	GO:0007186	G-protein coupled receptor signaling pathway
0.41	GO:0006030	chitin metabolic process
0.37	GO:0055085	transmembrane transport
0.33	GO:0008643	carbohydrate transport

0.52	GO:0001540	amyloid-beta binding
0.46	GO:0004930	G-protein coupled receptor activity
0.41	GO:0008061	chitin binding
0.37	GO:0022857	transmembrane transporter activity

0.46	GO:0005654	nucleoplasm
0.44	GO:0005887	integral component of plasma membrane
0.39	GO:0005576	extracellular region

tr|T1G2Q6|T1G2Q6_HELRO
Uncharacterized protein
Search

FADS2

0.81	Fatty acid desaturase A

0.63	GO:0006629	lipid metabolic process
0.52	GO:0055114	oxidation-reduction process
0.39	GO:0072330	monocarboxylic acid biosynthetic process
0.33	GO:0017144	drug metabolic process

0.53	GO:0016491	oxidoreductase activity
0.34	GO:0020037	heme binding
0.33	GO:0046872	metal ion binding

0.38	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0005887	integral component of plasma membrane

0.53

GO:0016491

tr|T1G2Q7|T1G2Q7_HELRO
DNA primase large subunit
Search

PRIM2

0.72	DNA primase large subunit

0.75	GO:0006269	DNA replication, synthesis of RNA primer
0.43	GO:0071897	DNA biosynthetic process
0.35	GO:0032201	telomere maintenance via semi-conservative replication
0.34	GO:0006302	double-strand break repair
0.34	GO:0000082	G1/S transition of mitotic cell cycle
0.34	GO:0006270	DNA replication initiation

0.78	GO:0003896	DNA primase activity
0.65	GO:0051539	4 iron, 4 sulfur cluster binding
0.52	GO:0046872	metal ion binding
0.51	GO:0003677	DNA binding
0.44	GO:0003887	DNA-directed DNA polymerase activity
0.34	GO:0005515	protein binding
0.32	GO:0003723	RNA binding

0.50	GO:0005658	alpha DNA polymerase:primase complex
0.43	GO:0055044	symplast
0.41	GO:0005911	cell-cell junction
0.34	GO:0005635	nuclear envelope
0.33	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

0.78

EC:2.7.7

GO:0003896

tr|T1G2Q8|T1G2Q8_HELRO
Uncharacterized protein
Search

0.71	GO:0034472	snRNA 3'-end processing
0.43	GO:0007179	transforming growth factor beta receptor signaling pathway
0.43	GO:0055114	oxidation-reduction process
0.41	GO:0006465	signal peptide processing
0.37	GO:0006351	transcription, DNA-templated
0.37	GO:1903506	regulation of nucleic acid-templated transcription
0.37	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:0010468	regulation of gene expression

0.60	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
0.53	GO:0005507	copper ion binding
0.38	GO:0003700	DNA binding transcription factor activity
0.37	GO:0008233	peptidase activity
0.36	GO:0003677	DNA binding

0.42	GO:0032039	integrator complex
0.41	GO:0005787	signal peptidase complex
0.41	GO:0005667	transcription factor complex
0.30	GO:0031224	intrinsic component of membrane

0.60

EC:1.14.17

GO:0016715

tr|T1G2Q9|T1G2Q9_HELRO
Uncharacterized protein
Search

NR2F1

0.90	Ovalbumin upstream promoter-transcription factor I

0.80	GO:0030522	intracellular receptor signaling pathway
0.79	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.47	GO:0072359	circulatory system development
0.46	GO:0051253	negative regulation of RNA metabolic process
0.46	GO:0010558	negative regulation of macromolecule biosynthetic process
0.46	GO:0031327	negative regulation of cellular biosynthetic process

0.82	GO:0004879	nuclear receptor activity
0.80	GO:0003707	steroid hormone receptor activity
0.64	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.49	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.45	GO:0001012	RNA polymerase II regulatory region DNA binding
0.43	GO:0003690	double-stranded DNA binding
0.41	GO:0001972	retinoic acid binding
0.40	GO:0042803	protein homodimerization activity
0.37	GO:0046982	protein heterodimerization activity

0.61	GO:0005634	nucleus
0.44	GO:0005829	cytosol
0.43	GO:0070013	intracellular organelle lumen
0.40	GO:0044446	intracellular organelle part

tr|T1G2R0|T1G2R0_HELRO
Uncharacterized protein
Search

0.54	Glucose-dependent insulinotropic receptor (Fragment)

0.35	GO:0000413	protein peptidyl-prolyl isomerization
0.35	GO:0006457	protein folding
0.34	GO:0006072	glycerol-3-phosphate metabolic process
0.34	GO:0045332	phospholipid translocation
0.33	GO:0006090	pyruvate metabolic process
0.32	GO:0055114	oxidation-reduction process

0.35	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.34	GO:0052590	sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity
0.34	GO:0017056	structural constituent of nuclear pore
0.34	GO:0004012	phospholipid-translocating ATPase activity
0.34	GO:0004742	dihydrolipoyllysine-residue acetyltransferase activity
0.33	GO:0005509	calcium ion binding
0.33	GO:0000287	magnesium ion binding
0.32	GO:0003723	RNA binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding

0.34	GO:1990204	oxidoreductase complex
0.34	GO:0005643	nuclear pore
0.34	GO:0044444	cytoplasmic part
0.30	GO:0031224	intrinsic component of membrane

0.35

GO:0003755

tr|T1G2R1|T1G2R1_HELRO
U6 snRNA phosphodiesterase
Search

0.72	U6 snRNA phosphodiesterase

0.85	GO:0034477	U6 snRNA 3'-end processing
0.70	GO:0008380	RNA splicing
0.66	GO:0006397	mRNA processing
0.64	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.48	GO:0030223	neutrophil differentiation
0.45	GO:0043484	regulation of RNA splicing
0.34	GO:0006414	translational elongation

0.64	GO:0004518	nuclease activity
0.37	GO:0140098	catalytic activity, acting on RNA
0.34	GO:0005515	protein binding
0.33	GO:0003735	structural constituent of ribosome

0.59	GO:0005634	nucleus
0.33	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.64

GO:0004518

tr|T1G2R2|T1G2R2_HELRO
Uncharacterized protein
Search

0.53	Transcription factor 4 (Fragment)

0.48	GO:0045666	positive regulation of neuron differentiation
0.48	GO:0042118	endothelial cell activation
0.48	GO:1900746	regulation of vascular endothelial growth factor signaling pathway
0.46	GO:0016525	negative regulation of angiogenesis
0.46	GO:0045944	positive regulation of transcription by RNA polymerase II
0.45	GO:0006367	transcription initiation from RNA polymerase II promoter
0.44	GO:0065004	protein-DNA complex assembly
0.44	GO:0000122	negative regulation of transcription by RNA polymerase II

0.67	GO:0046983	protein dimerization activity
0.51	GO:0001087	transcription factor activity, TFIIB-class binding
0.50	GO:0001011	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting
0.49	GO:0001093	TFIIB-class transcription factor binding
0.48	GO:0070888	E-box binding
0.47	GO:0043621	protein self-association
0.46	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.45	GO:0043425	bHLH transcription factor binding
0.45	GO:0003714	transcription corepressor activity
0.44	GO:0003682	chromatin binding

0.46	GO:0005667	transcription factor complex
0.41	GO:0005634	nucleus
0.36	GO:0000785	chromatin
0.35	GO:0043233	organelle lumen
0.33	GO:0032993	protein-DNA complex
0.30	GO:0016020	membrane

tr|T1G2R3|T1G2R3_HELRO
Uncharacterized protein
Search

tr|T1G2R4|T1G2R4_HELRO
Uncharacterized protein
Search

tr|T1G2R5|T1G2R5_HELRO
Uncharacterized protein
Search

0.44

Paxillin

0.74	GO:0007160	cell-matrix adhesion
0.44	GO:2001141	regulation of RNA biosynthetic process

0.55	GO:0003712	transcription cofactor activity
0.54	GO:0046872	metal ion binding

0.69	GO:0005856	cytoskeleton
0.58	GO:0005925	focal adhesion
0.46	GO:0043234	protein complex
0.45	GO:0044446	intracellular organelle part

tr|T1G2R6|T1G2R6_HELRO
Uncharacterized protein
Search

0.53	Glucose-dependent insulinotropic receptor

0.36	GO:0070647	protein modification by small protein conjugation or removal
0.34	GO:0042073	intraciliary transport
0.34	GO:0060271	cilium assembly
0.34	GO:0006508	proteolysis
0.33	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:0006351	transcription, DNA-templated
0.33	GO:0006313	transposition, DNA-mediated
0.33	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.33	GO:0015074	DNA integration
0.33	GO:0006355	regulation of transcription, DNA-templated

0.36	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.35	GO:0004842	ubiquitin-protein transferase activity
0.34	GO:0031683	G-protein beta/gamma-subunit complex binding
0.34	GO:0015631	tubulin binding
0.33	GO:0043565	sequence-specific DNA binding
0.33	GO:0008270	zinc ion binding
0.33	GO:0003700	DNA binding transcription factor activity
0.33	GO:0004636	phosphoribosyl-ATP diphosphatase activity
0.33	GO:0003924	GTPase activity
0.33	GO:0017076	purine nucleotide binding

0.35	GO:0030992	intraciliary transport particle B
0.34	GO:0031514	motile cilium
0.33	GO:0043231	intracellular membrane-bounded organelle
0.32	GO:0044444	cytoplasmic part
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.33	EC:3.6.1.31	GO:0004636
0.35	KEGG:R03876	GO:0004842

tr|T1G2R7|T1G2R7_HELRO
Carboxylic ester hydrolase
Search

ACHE1

0.44	Carboxylic ester hydrolase

0.45	GO:0006581	acetylcholine catabolic process
0.42	GO:0007271	synaptic transmission, cholinergic
0.39	GO:0071405	cellular response to methanol
0.38	GO:0001975	response to amphetamine
0.37	GO:0007528	neuromuscular junction development
0.37	GO:0045471	response to ethanol
0.37	GO:0009749	response to glucose
0.37	GO:0030239	myofibril assembly
0.37	GO:0050803	regulation of synapse structure or activity
0.36	GO:0048666	neuron development

0.81	GO:0004104	cholinesterase activity
0.33	GO:0016298	lipase activity
0.32	GO:0005515	protein binding

0.42	GO:0043083	synaptic cleft
0.33	GO:0005794	Golgi apparatus
0.33	GO:0005783	endoplasmic reticulum
0.30	GO:0016020	membrane

0.81

EC:3.1.1.8

GO:0004104

tr|T1G2R8|T1G2R8_HELRO
Uncharacterized protein
Search

0.46	Phosphatase and actin regulator

0.76	GO:0032515	negative regulation of phosphoprotein phosphatase activity
0.43	GO:0030036	actin cytoskeleton organization
0.39	GO:0006418	tRNA aminoacylation for protein translation
0.38	GO:2001045	negative regulation of integrin-mediated signaling pathway
0.38	GO:0061386	closure of optic fissure
0.38	GO:0006928	movement of cell or subcellular component
0.38	GO:0051674	localization of cell
0.37	GO:0048484	enteric nervous system development
0.37	GO:0014032	neural crest cell development
0.37	GO:0001843	neural tube closure

0.76	GO:0004864	protein phosphatase inhibitor activity
0.68	GO:0003779	actin binding
0.60	GO:0008157	protein phosphatase 1 binding
0.39	GO:0016875	ligase activity, forming carbon-oxygen bonds
0.38	GO:0140101	catalytic activity, acting on a tRNA
0.38	GO:0072542	protein phosphatase activator activity
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0015631	tubulin binding

0.37	GO:0030027	lamellipodium
0.35	GO:0005829	cytosol
0.35	GO:0031092	platelet alpha granule membrane
0.34	GO:0005634	nucleus
0.34	GO:0000922	spindle pole
0.33	GO:0005815	microtubule organizing center
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.39

EC:6.1

GO:0016875

tr|T1G2R9|T1G2R9_HELRO
Uncharacterized protein
Search

0.68	Protein-glucosylgalactosylhydroxylysine glucosidase

0.60	GO:0005975	carbohydrate metabolic process
0.34	GO:0071497	cellular response to freezing
0.34	GO:0071465	cellular response to desiccation
0.34	GO:0071361	cellular response to ethanol
0.32	GO:0044248	cellular catabolic process
0.32	GO:1901575	organic substance catabolic process

0.53	GO:0047402	protein-glucosylgalactosylhydroxylysine glucosidase activity
0.37	GO:0030246	carbohydrate binding
0.33	GO:0008801	beta-phosphoglucomutase activity
0.33	GO:0004555	alpha,alpha-trehalase activity
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0043565	sequence-specific DNA binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.45	GO:0005618	cell wall
0.42	GO:0005829	cytosol
0.34	GO:0030287	cell wall-bounded periplasmic space
0.33	GO:0000324	fungal-type vacuole
0.33	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.53	EC:3.2.1.107	GO:0047402
0.33	KEGG:R02728	GO:0008801

tr|T1G2S0|T1G2S0_HELRO
Uncharacterized protein
Search

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.36	GO:0090278	negative regulation of peptide hormone secretion
0.35	GO:0070328	triglyceride homeostasis
0.33	GO:0018108	peptidyl-tyrosine phosphorylation
0.32	GO:0006518	peptide metabolic process
0.32	GO:0043604	amide biosynthetic process
0.32	GO:1901566	organonitrogen compound biosynthetic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process

0.72	GO:0004930	G-protein coupled receptor activity
0.49	GO:0001653	peptide receptor activity
0.33	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.32	GO:0003735	structural constituent of ribosome
0.32	GO:0005515	protein binding

0.35	GO:0043025	neuronal cell body
0.34	GO:0005887	integral component of plasma membrane
0.32	GO:0005840	ribosome

0.33

GO:0004715

tr|T1G2S1|T1G2S1_HELRO
Uncharacterized protein
Search

0.19	RNA binding motif protein, X-linked

0.45	GO:0006509	membrane protein ectodomain proteolysis
0.44	GO:0071347	cellular response to interleukin-1
0.44	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.42	GO:0045944	positive regulation of transcription by RNA polymerase II
0.42	GO:0006366	transcription by RNA polymerase II
0.41	GO:0051259	protein oligomerization
0.38	GO:0048025	negative regulation of mRNA splicing, via spliceosome
0.38	GO:0048026	positive regulation of mRNA splicing, via spliceosome
0.38	GO:0008380	RNA splicing
0.37	GO:0006397	mRNA processing

0.59	GO:0003723	RNA binding
0.44	GO:0001047	core promoter binding
0.42	GO:0003682	chromatin binding
0.41	GO:0019904	protein domain specific binding
0.40	GO:0042802	identical protein binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0032561	guanyl ribonucleotide binding
0.33	GO:0016853	isomerase activity
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0016787	hydrolase activity

0.46	GO:0044530	supraspliceosomal complex
0.45	GO:0019013	viral nucleocapsid
0.44	GO:0005719	nuclear euchromatin
0.43	GO:0071013	catalytic step 2 spliceosome
0.43	GO:0070062	extracellular exosome
0.37	GO:0005852	eukaryotic translation initiation factor 3 complex
0.33	GO:0016282	eukaryotic 43S preinitiation complex
0.33	GO:0033290	eukaryotic 48S preinitiation complex
0.33	GO:0005654	nucleoplasm
0.33	GO:0005789	endoplasmic reticulum membrane

0.33

EC:5

GO:0016853

tr|T1G2S2|T1G2S2_HELRO
Uncharacterized protein
Search

0.68	GO:0051290	protein heterotetramerization
0.68	GO:0007346	regulation of mitotic cell cycle
0.65	GO:0000082	G1/S transition of mitotic cell cycle
0.64	GO:0007052	mitotic spindle organization
0.64	GO:0051225	spindle assembly
0.61	GO:0051783	regulation of nuclear division
0.59	GO:0006607	NLS-bearing protein import into nucleus
0.59	GO:0010564	regulation of cell cycle process
0.57	GO:0007059	chromosome segregation
0.57	GO:0046822	regulation of nucleocytoplasmic transport

0.71	GO:0043199	sulfate binding
0.71	GO:0005087	Ran guanyl-nucleotide exchange factor activity
0.69	GO:0003682	chromatin binding
0.62	GO:0042393	histone binding
0.59	GO:0046982	protein heterodimerization activity
0.57	GO:0044877	macromolecular complex binding
0.46	GO:0003677	DNA binding
0.43	GO:0008157	protein phosphatase 1 binding
0.41	GO:0019888	protein phosphatase regulator activity
0.40	GO:0003779	actin binding

0.68	GO:0000793	condensed chromosome
0.66	GO:0031965	nuclear membrane
0.59	GO:0000790	nuclear chromatin
0.58	GO:0005654	nucleoplasm
0.49	GO:0043234	protein complex
0.44	GO:0005737	cytoplasm
0.37	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016021	integral component of membrane

tr|T1G2S3|T1G2S3_HELRO
Uncharacterized protein
Search

0.37	GO:0007417	central nervous system development
0.37	GO:0048513	animal organ development
0.34	GO:0061351	neural precursor cell proliferation
0.34	GO:0001841	neural tube formation
0.34	GO:0060070	canonical Wnt signaling pathway
0.34	GO:0060322	head development
0.34	GO:0050767	regulation of neurogenesis
0.34	GO:0042127	regulation of cell proliferation

0.51	GO:0003676	nucleic acid binding
0.36	GO:0004075	biotin carboxylase activity
0.34	GO:0046872	metal ion binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.36

EC:6.3.4.14

GO:0004075

tr|T1G2S4|T1G2S4_HELRO
Uncharacterized protein
Search

TMEM50B

0.77	HCV p7-trans-regulated protein 3

0.33

GO:0055085

transmembrane transport

0.34	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.49	GO:0005783	endoplasmic reticulum
0.39	GO:0000139	Golgi membrane
0.38	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

tr|T1G2S5|T1G2S5_HELRO
Uncharacterized protein
Search

0.54	GO:0006468	protein phosphorylation
0.38	GO:0006259	DNA metabolic process
0.36	GO:0061723	glycophagy
0.36	GO:0000413	protein peptidyl-prolyl isomerization
0.36	GO:0061709	reticulophagy
0.36	GO:0045793	positive regulation of cell size
0.36	GO:0030242	autophagy of peroxisome
0.36	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway
0.36	GO:0000422	autophagy of mitochondrion
0.36	GO:0001889	liver development

0.59	GO:0004674	protein serine/threonine kinase activity
0.48	GO:0032559	adenyl ribonucleotide binding
0.47	GO:0008144	drug binding
0.47	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0008663	2',3'-cyclic-nucleotide 2'-phosphodiesterase activity
0.40	GO:0008854	exodeoxyribonuclease V activity
0.39	GO:0004381	fucosylgalactoside 3-alpha-galactosyltransferase activity
0.37	GO:0009035	Type I site-specific deoxyribonuclease activity
0.36	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.35	GO:0032947	protein complex scaffold activity

0.57	GO:0031514	motile cilium
0.36	GO:1990316	Atg1/ULK1 kinase complex
0.36	GO:0034045	phagophore assembly site membrane
0.35	GO:0031965	nuclear membrane
0.34	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.59

GO:0004674

tr|T1G2S6|T1G2S6_HELRO
Uncharacterized protein
Search

0.53	Microtubule-associated serine/threonine-protein kinase 2 (Fragment)

0.63

GO:0006468

protein phosphorylation

0.70	GO:0004674	protein serine/threonine kinase activity
0.63	GO:0000287	magnesium ion binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0031224

intrinsic component of membrane

0.70

GO:0004674

tr|T1G2S7|T1G2S7_HELRO
Uncharacterized protein
Search

SETD9

0.74	SET domain containing 9

tr|T1G2S8|T1G2S8_HELRO
Uncharacterized protein
Search

POLR1C

0.89	RNA polymerase I subunit C

0.58	GO:0006351	transcription, DNA-templated
0.45	GO:0048703	embryonic viscerocranium morphogenesis
0.44	GO:0051216	cartilage development
0.40	GO:0042254	ribosome biogenesis
0.36	GO:0040029	regulation of gene expression, epigenetic
0.35	GO:0032481	positive regulation of type I interferon production
0.34	GO:0016458	gene silencing
0.34	GO:0006325	chromatin organization
0.34	GO:0010628	positive regulation of gene expression
0.34	GO:0045892	negative regulation of transcription, DNA-templated

0.70	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.68	GO:0046983	protein dimerization activity
0.53	GO:0003677	DNA binding

0.56	GO:0005736	DNA-directed RNA polymerase I complex
0.55	GO:0005666	DNA-directed RNA polymerase III complex
0.33	GO:0005829	cytosol

0.70

GO:0003899

tr|T1G2S9|T1G2S9_HELRO
Uncharacterized protein
Search

0.70	GO:0071805	potassium ion transmembrane transport
0.47	GO:0030322	stabilization of membrane potential
0.34	GO:0043044	ATP-dependent chromatin remodeling
0.33	GO:0016925	protein sumoylation
0.32	GO:0032259	methylation

0.73	GO:0005267	potassium channel activity
0.47	GO:0022842	narrow pore channel activity
0.33	GO:0005509	calcium ion binding
0.32	GO:0003677	DNA binding
0.32	GO:0008168	methyltransferase activity
0.32	GO:0016787	hydrolase activity

0.41	GO:0005887	integral component of plasma membrane
0.34	GO:0016514	SWI/SNF complex

0.32

GO:0008168

tr|T1G2T0|T1G2T0_HELRO
Uncharacterized protein
Search

0.45	GO:0000042	protein targeting to Golgi
0.44	GO:0051642	centrosome localization
0.44	GO:0018022	peptidyl-lysine methylation
0.43	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.43	GO:0072385	minus-end-directed organelle transport along microtubule
0.43	GO:0070507	regulation of microtubule cytoskeleton organization
0.42	GO:0072393	microtubule anchoring at microtubule organizing center
0.33	GO:0051028	mRNA transport

0.85	GO:0008093	cytoskeletal adaptor activity
0.84	GO:0070840	dynein complex binding
0.44	GO:0016279	protein-lysine N-methyltransferase activity
0.42	GO:0034452	dynactin binding
0.41	GO:0051959	dynein light intermediate chain binding
0.40	GO:0017137	Rab GTPase binding

0.45	GO:0005642	annulate lamellae
0.42	GO:0005813	centrosome
0.42	GO:0005643	nuclear pore
0.40	GO:0005794	Golgi apparatus
0.39	GO:0005829	cytosol
0.39	GO:0031410	cytoplasmic vesicle
0.36	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.44

GO:0016279

tr|T1G2T1|T1G2T1_HELRO
Uncharacterized protein
Search

RAB33B

0.83	Putative rab subfamily protein of small gtpase

0.56	GO:1903434	negative regulation of constitutive secretory pathway
0.55	GO:2000156	regulation of retrograde vesicle-mediated transport, Golgi to ER
0.54	GO:1903358	regulation of Golgi organization
0.53	GO:0000042	protein targeting to Golgi
0.52	GO:2000785	regulation of autophagosome assembly
0.51	GO:0048705	skeletal system morphogenesis
0.50	GO:0000045	autophagosome assembly
0.46	GO:0019882	antigen processing and presentation
0.36	GO:0050678	regulation of epithelial cell proliferation
0.35	GO:0001558	regulation of cell growth

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0004767	sphingomyelin phosphodiesterase activity
0.34	GO:0005515	protein binding
0.33	GO:0003723	RNA binding

0.54	GO:0005796	Golgi lumen
0.37	GO:0000139	Golgi membrane
0.36	GO:0070062	extracellular exosome
0.33	GO:0005886	plasma membrane

0.35	EC:3.1.4.12	GO:0004767
0.35	KEGG:R02541	GO:0004767

tr|T1G2T2|T1G2T2_HELRO
Uncharacterized protein
Search

0.65	DENN domain containing 4C

0.69	GO:0032869	cellular response to insulin stimulus
0.68	GO:0072659	protein localization to plasma membrane
0.58	GO:0065009	regulation of molecular function
0.39	GO:0009966	regulation of signal transduction
0.38	GO:0015031	protein transport

0.71	GO:0017112	Rab guanyl-nucleotide exchange factor activity
0.41	GO:0005179	hormone activity

0.73	GO:0032593	insulin-responsive compartment
0.67	GO:0030904	retromer complex
0.63	GO:0000813	ESCRT I complex
0.57	GO:0005829	cytosol
0.48	GO:0005886	plasma membrane
0.40	GO:0030659	cytoplasmic vesicle membrane
0.38	GO:0005576	extracellular region
0.37	GO:0005794	Golgi apparatus
0.30	GO:0031224	intrinsic component of membrane

tr|T1G2T3|T1G2T3_HELRO
Uncharacterized protein
Search

RPL14

0.60	Ribosomal protein L14

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.49	GO:0042273	ribosomal large subunit biogenesis
0.41	GO:0016072	rRNA metabolic process
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.33	GO:0019083	viral transcription

0.64	GO:0003735	structural constituent of ribosome
0.45	GO:0045296	cadherin binding
0.40	GO:0003723	RNA binding
0.32	GO:0016787	hydrolase activity

0.61	GO:0005840	ribosome
0.44	GO:0044445	cytosolic part
0.39	GO:0044446	intracellular organelle part
0.36	GO:0070062	extracellular exosome
0.34	GO:0005791	rough endoplasmic reticulum
0.34	GO:0098562	cytoplasmic side of membrane
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0098588	bounding membrane of organelle
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016787

tr|T1G2T4|T1G2T4_HELRO
Uncharacterized protein
Search

SLC33A1

0.85	Acetyl-coenzyme A transporter

0.85	GO:0015876	acetyl-CoA transport
0.46	GO:0060395	SMAD protein signal transduction
0.46	GO:0030509	BMP signaling pathway
0.39	GO:1902600	hydrogen ion transmembrane transport
0.36	GO:0021955	central nervous system neuron axonogenesis
0.36	GO:0030514	negative regulation of BMP signaling pathway
0.32	GO:0005975	carbohydrate metabolic process

0.85	GO:0008521	acetyl-CoA transmembrane transporter activity
0.43	GO:0015295	solute:proton symporter activity
0.33	GO:0016746	transferase activity, transferring acyl groups
0.33	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds

0.40	GO:0005887	integral component of plasma membrane
0.34	GO:0005789	endoplasmic reticulum membrane

0.33

EC:2.3

GO:0016746

tr|T1G2T5|T1G2T5_HELRO
Phosphodiesterase
Search

PDE4B

0.52	Phosphodiesterase

0.60	GO:0007165	signal transduction
0.51	GO:0009214	cyclic nucleotide catabolic process
0.51	GO:0032743	positive regulation of interleukin-2 production
0.51	GO:0009154	purine ribonucleotide catabolic process
0.51	GO:0032729	positive regulation of interferon-gamma production
0.49	GO:0001780	neutrophil homeostasis
0.49	GO:0030593	neutrophil chemotaxis
0.48	GO:0046058	cAMP metabolic process
0.48	GO:0002253	activation of immune response
0.48	GO:0071222	cellular response to lipopolysaccharide

0.79	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.54	GO:0046872	metal ion binding
0.51	GO:0030552	cAMP binding
0.46	GO:0043015	gamma-tubulin binding
0.38	GO:0044325	ion channel binding
0.37	GO:0097110	scaffold protein binding
0.37	GO:0051117	ATPase binding
0.36	GO:0005516	calmodulin binding
0.33	GO:0008144	drug binding
0.33	GO:0003924	GTPase activity

0.48	GO:0060076	excitatory synapse
0.47	GO:0043197	dendritic spine
0.47	GO:0014069	postsynaptic density
0.47	GO:0000930	gamma-tubulin complex
0.46	GO:0008021	synaptic vesicle
0.46	GO:0005813	centrosome
0.43	GO:0005829	cytosol
0.39	GO:0071944	cell periphery
0.38	GO:0034704	calcium channel complex
0.36	GO:0031965	nuclear membrane

0.79

GO:0004114

tr|T1G2T6|T1G2T6_HELRO
Delta-like protein
Search

0.63	GO:0007219	Notch signaling pathway
0.61	GO:0007275	multicellular organism development
0.46	GO:0098742	cell-cell adhesion via plasma-membrane adhesion molecules
0.46	GO:0030154	cell differentiation
0.44	GO:0050793	regulation of developmental process
0.41	GO:0097150	neuronal stem cell population maintenance
0.41	GO:0034351	negative regulation of glial cell apoptotic process
0.41	GO:0032693	negative regulation of interleukin-10 production
0.41	GO:2000505	regulation of energy homeostasis
0.41	GO:0060429	epithelium development

0.70	GO:0005509	calcium ion binding
0.50	GO:0005112	Notch binding
0.41	GO:0030957	Tat protein binding
0.40	GO:0097110	scaffold protein binding
0.36	GO:0004872	receptor activity
0.34	GO:0008270	zinc ion binding
0.34	GO:0003700	DNA binding transcription factor activity
0.34	GO:0004866	endopeptidase inhibitor activity
0.34	GO:0005201	extracellular matrix structural constituent
0.34	GO:0004175	endopeptidase activity

0.40	GO:0005886	plasma membrane
0.40	GO:0045177	apical part of cell
0.40	GO:0005912	adherens junction
0.39	GO:0031410	cytoplasmic vesicle
0.39	GO:0098857	membrane microdomain
0.35	GO:0005576	extracellular region
0.35	GO:0005634	nucleus
0.34	GO:0009986	cell surface
0.34	GO:0043296	apical junction complex
0.34	GO:0005764	lysosome

0.32

GO:0016491

tr|T1G2T7|T1G2T7_HELRO
Uncharacterized protein
Search

tr|T1G2T8|T1G2T8_HELRO
Uncharacterized protein
Search

0.44	Glucose-dependent insulinotropic receptor (Fragment)

0.35	GO:0036211	protein modification process
0.34	GO:0016192	vesicle-mediated transport
0.34	GO:0006796	phosphate-containing compound metabolic process
0.34	GO:0044267	cellular protein metabolic process
0.34	GO:0140056	organelle localization by membrane tethering
0.33	GO:0065007	biological regulation
0.33	GO:0006270	DNA replication initiation
0.33	GO:0007571	age-dependent general metabolic decline
0.33	GO:0030154	cell differentiation
0.33	GO:0032940	secretion by cell

0.34	GO:0016772	transferase activity, transferring phosphorus-containing groups
0.34	GO:0140096	catalytic activity, acting on a protein
0.34	GO:0008144	drug binding
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0043168	anion binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0004999	vasoactive intestinal polypeptide receptor activity
0.33	GO:0003677	DNA binding
0.33	GO:0005509	calcium ion binding
0.33	GO:0030234	enzyme regulator activity

0.34	GO:0005634	nucleus
0.33	GO:0043234	protein complex
0.33	GO:0044444	cytoplasmic part
0.33	GO:0099023	tethering complex
0.33	GO:0048475	coated membrane
0.33	GO:1990204	oxidoreductase complex
0.32	GO:0005694	chromosome
0.30	GO:0016021	integral component of membrane

0.34	EC:2.7	GO:0016772
0.33	KEGG:R01730	GO:0004665

tr|T1G2T9|T1G2T9_HELRO
Uncharacterized protein
Search

tr|T1G2U0|T1G2U0_HELRO
Defective in cullin neddylation protein
Search

0.38	Defective in cullin neddylation protein

0.60	GO:0045116	protein neddylation
0.59	GO:0051443	positive regulation of ubiquitin-protein transferase activity

0.62	GO:0097602	cullin family protein binding
0.61	GO:0031624	ubiquitin conjugating enzyme binding
0.58	GO:0032182	ubiquitin-like protein binding
0.38	GO:0016874	ligase activity

0.55	GO:0000151	ubiquitin ligase complex
0.30	GO:0044425	membrane part

0.38

GO:0016874

tr|T1G2U1|T1G2U1_HELRO
Uncharacterized protein
Search

0.94	Normal mucosa of esophagus specific 1

0.30

GO:0044425

membrane part

tr|T1G2U2|T1G2U2_HELRO
Uncharacterized protein
Search

0.79	Signal peptidase complex subunit

0.80	GO:0006465	signal peptide processing
0.41	GO:0045047	protein targeting to ER
0.34	GO:0006030	chitin metabolic process
0.33	GO:0008299	isoprenoid biosynthetic process

0.61	GO:0008233	peptidase activity
0.34	GO:0008061	chitin binding
0.34	GO:0004452	isopentenyl-diphosphate delta-isomerase activity
0.33	GO:0016887	ATPase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.82	GO:0005787	signal peptidase complex
0.34	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

0.61	EC:3.4	GO:0008233
0.34	KEGG:R01123	GO:0004452

tr|T1G2U3|T1G2U3_HELRO
Uncharacterized protein
Search

0.97	SRY-box containing transcription factor 21 (Fragment)

0.54	GO:0007399	nervous system development
0.46	GO:1903506	regulation of nucleic acid-templated transcription
0.46	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.46	GO:0010468	regulation of gene expression
0.42	GO:0060573	cell fate specification involved in pattern specification
0.42	GO:0002089	lens morphogenesis in camera-type eye
0.41	GO:1990830	cellular response to leukemia inhibitory factor
0.41	GO:0009953	dorsal/ventral pattern formation
0.41	GO:0048518	positive regulation of biological process
0.40	GO:0060322	head development

0.55	GO:0003677	DNA binding
0.41	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.40	GO:0001067	regulatory region nucleic acid binding
0.35	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.34	GO:0003682	chromatin binding
0.34	GO:0046982	protein heterodimerization activity

0.61	GO:0005634	nucleus
0.35	GO:0005667	transcription factor complex
0.33	GO:0044446	intracellular organelle part
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.35

GO:0032440

tr|T1G2U4|T1G2U4_HELRO
Uncharacterized protein
Search

0.66	GO:0045995	regulation of embryonic development
0.62	GO:0030334	regulation of cell migration
0.60	GO:0030155	regulation of cell adhesion
0.60	GO:0007155	cell adhesion
0.49	GO:0007275	multicellular organism development
0.47	GO:0009888	tissue development
0.47	GO:0009653	anatomical structure morphogenesis
0.46	GO:0030154	cell differentiation
0.45	GO:0008104	protein localization
0.44	GO:0120036	plasma membrane bounded cell projection organization

0.58	GO:0005102	receptor binding
0.45	GO:0032403	protein complex binding
0.42	GO:0017022	myosin binding
0.42	GO:0050839	cell adhesion molecule binding
0.40	GO:0042803	protein homodimerization activity
0.39	GO:0005509	calcium ion binding
0.37	GO:0004930	G-protein coupled receptor activity
0.36	GO:0005198	structural molecule activity
0.36	GO:0016849	phosphorus-oxygen lyase activity
0.33	GO:1901265	nucleoside phosphate binding

0.52	GO:0005604	basement membrane
0.44	GO:0060171	stereocilium membrane
0.44	GO:0002142	stereocilia ankle link complex
0.44	GO:0043083	synaptic cleft
0.44	GO:1990696	USH2 complex
0.44	GO:1990075	periciliary membrane compartment
0.43	GO:0001917	photoreceptor inner segment
0.43	GO:0032391	photoreceptor connecting cilium
0.42	GO:0036064	ciliary basal body
0.41	GO:0016324	apical plasma membrane

0.36

EC:4.6

GO:0016849

tr|T1G2U5|T1G2U5_HELRO
Uncharacterized protein
Search

0.85	MBT domain-containing protein 1

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0045814	negative regulation of gene expression, epigenetic
0.55	GO:0016458	gene silencing
0.52	GO:0006325	chromatin organization
0.52	GO:1902679	negative regulation of RNA biosynthetic process
0.37	GO:0048706	embryonic skeletal system development
0.35	GO:0007398	ectoderm development
0.35	GO:0035067	negative regulation of histone acetylation
0.35	GO:0031062	positive regulation of histone methylation

0.71	GO:0140034	methylation-dependent protein binding
0.67	GO:0042393	histone binding
0.62	GO:0008270	zinc ion binding
0.37	GO:0003677	DNA binding
0.35	GO:1990841	promoter-specific chromatin binding
0.35	GO:0005044	scavenger receptor activity
0.34	GO:0008168	methyltransferase activity

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.34

GO:0008168

tr|T1G2U6|T1G2U6_HELRO
Uncharacterized protein
Search

tr|T1G2U7|T1G2U7_HELRO
Uncharacterized protein
Search

0.11	DDB1 and CUL4 associated factor 6

tr|T1G2U8|T1G2U8_HELRO
Uncharacterized protein
Search

0.49	LIM domain only protein 3

0.46	GO:0035483	gastric emptying
0.45	GO:0036011	imaginal disc-derived leg segmentation
0.44	GO:0042220	response to cocaine
0.44	GO:0022416	chaeta development
0.44	GO:0045475	locomotor rhythm
0.43	GO:0007476	imaginal disc-derived wing morphogenesis
0.43	GO:0008593	regulation of Notch signaling pathway
0.41	GO:1903508	positive regulation of nucleic acid-templated transcription
0.40	GO:0010628	positive regulation of gene expression
0.40	GO:0022414	reproductive process

0.54	GO:0046872	metal ion binding
0.36	GO:0005515	protein binding
0.32	GO:0016740	transferase activity

0.35	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.32

GO:0016740

tr|T1G2U9|T1G2U9_HELRO
Uncharacterized protein
Search

CDC14B

0.87	Dual specificity protein phosphatase CDC14A

0.75	GO:0035335	peptidyl-tyrosine dephosphorylation
0.47	GO:0072425	signal transduction involved in G2 DNA damage checkpoint
0.46	GO:1904668	positive regulation of ubiquitin protein ligase activity
0.45	GO:0051256	mitotic spindle midzone assembly
0.45	GO:0060271	cilium assembly
0.45	GO:0051301	cell division
0.45	GO:0071850	mitotic cell cycle arrest
0.43	GO:0007096	regulation of exit from mitosis
0.33	GO:0006281	DNA repair

0.79	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.75	GO:0004725	protein tyrosine phosphatase activity
0.46	GO:0004722	protein serine/threonine phosphatase activity
0.33	GO:0005515	protein binding

0.45	GO:0005730	nucleolus
0.44	GO:0005819	spindle
0.44	GO:0005654	nucleoplasm
0.43	GO:0005813	centrosome
0.38	GO:0000793	condensed chromosome
0.37	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.79

EC:3.1.3

GO:0008138

tr|T1G2V0|T1G2V0_HELRO
Uncharacterized protein
Search

CFAP61

0.80	Cilia and flagella associated protein 61

0.48	GO:0003341	cilium movement
0.47	GO:0044782	cilium organization
0.42	GO:0055114	oxidation-reduction process
0.33	GO:0046939	nucleotide phosphorylation

0.42	GO:0016491	oxidoreductase activity
0.34	GO:0004017	adenylate kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.71	GO:0031514	motile cilium
0.53	GO:0001536	radial spoke stalk
0.30	GO:0031224	intrinsic component of membrane

0.42

GO:0016491

tr|T1G2V1|T1G2V1_HELRO
Uncharacterized protein
Search

0.78	Hyperpolarization-activated cyclic nucleotide-modulated cation channel splice variant ABs-II

0.69	GO:0071805	potassium ion transmembrane transport
0.61	GO:0043269	regulation of ion transport
0.60	GO:0034762	regulation of transmembrane transport
0.47	GO:0016057	regulation of membrane potential in photoreceptor cell
0.47	GO:0007637	proboscis extension reflex
0.46	GO:0071632	optomotor response
0.46	GO:0050802	circadian sleep/wake cycle, sleep
0.46	GO:0071484	cellular response to light intensity
0.46	GO:0045938	positive regulation of circadian sleep/wake cycle, sleep
0.45	GO:0050433	regulation of catecholamine secretion

0.73	GO:0005249	voltage-gated potassium channel activity
0.35	GO:0004692	cGMP-dependent protein kinase activity
0.32	GO:0003677	DNA binding

0.36	GO:0005887	integral component of plasma membrane
0.33	GO:0005634	nucleus

0.35

EC:2.7.11.12

GO:0004692

tr|T1G2V2|T1G2V2_HELRO
Uncharacterized protein
Search

0.53	ULK/FUSED protein kinase

0.63	GO:0006468	protein phosphorylation
0.52	GO:0007228	positive regulation of hh target transcription factor activity
0.50	GO:0003351	epithelial cilium movement
0.50	GO:0045880	positive regulation of smoothened signaling pathway
0.49	GO:0044782	cilium organization
0.49	GO:0120031	plasma membrane bounded cell projection assembly
0.48	GO:0007275	multicellular organism development
0.47	GO:0060322	head development
0.46	GO:0070925	organelle assembly
0.43	GO:0007112	male meiosis cytokinesis

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0008134	transcription factor binding
0.42	GO:0019894	kinesin binding
0.34	GO:0015179	L-amino acid transmembrane transporter activity
0.33	GO:0046872	metal ion binding
0.33	GO:0015297	antiporter activity
0.33	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

0.43	GO:0005829	cytosol
0.42	GO:0009524	phragmoplast
0.41	GO:0005634	nucleus
0.34	GO:0035301	Hedgehog signaling complex
0.33	GO:0005929	cilium
0.33	GO:0005887	integral component of plasma membrane

0.33

GO:0016705

tr|T1G2V3|T1G2V3_HELRO
Uncharacterized protein
Search

0.60	Slingshot protein phosphatase 1a (Fragment)

0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.58	GO:0030036	actin cytoskeleton organization
0.43	GO:0010591	regulation of lamellipodium assembly
0.42	GO:0050770	regulation of axonogenesis
0.41	GO:0008064	regulation of actin polymerization or depolymerization
0.41	GO:0071318	cellular response to ATP
0.38	GO:0000902	cell morphogenesis
0.37	GO:0032268	regulation of cellular protein metabolic process
0.35	GO:1904719	positive regulation of AMPA glutamate receptor clustering
0.35	GO:0098976	excitatory chemical synaptic transmission

0.79	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.75	GO:0004725	protein tyrosine phosphatase activity
0.42	GO:0003779	actin binding
0.34	GO:0033549	MAP kinase phosphatase activity
0.34	GO:0046983	protein dimerization activity
0.33	GO:0043565	sequence-specific DNA binding
0.32	GO:0003700	DNA binding transcription factor activity

0.35	GO:0005737	cytoplasm
0.35	GO:0005886	plasma membrane
0.34	GO:0030426	growth cone
0.34	GO:0005856	cytoskeleton
0.34	GO:0005925	focal adhesion
0.34	GO:0031252	cell leading edge
0.34	GO:0045177	apical part of cell
0.32	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.79

EC:3.1.3

GO:0008138

tr|T1G2V4|T1G2V4_HELRO
Uncharacterized protein
Search

0.49	Zinc finger MYM-type protein 1

0.68

GO:0046983

protein dimerization activity

0.30

GO:0044425

membrane part

tr|T1G2V5|T1G2V5_HELRO
Guanylate cyclase
Search

0.46	Guanylate cyclase

0.80	GO:0006182	cGMP biosynthetic process
0.62	GO:0006468	protein phosphorylation
0.61	GO:0035556	intracellular signal transduction
0.44	GO:0060038	cardiac muscle cell proliferation
0.37	GO:0007168	receptor guanylyl cyclase signaling pathway
0.35	GO:0042127	regulation of cell proliferation
0.35	GO:0045792	negative regulation of cell size
0.34	GO:0007030	Golgi organization
0.34	GO:0045931	positive regulation of mitotic cell cycle
0.33	GO:0035725	sodium ion transmembrane transport

0.80	GO:0004383	guanylate cyclase activity
0.62	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0004016	adenylate cyclase activity
0.37	GO:0016941	natriuretic peptide receptor activity
0.34	GO:0005272	sodium channel activity
0.33	GO:0004930	G-protein coupled receptor activity
0.33	GO:0051287	NAD binding

0.44	GO:0005622	intracellular
0.37	GO:0043234	protein complex
0.36	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.80

GO:0004383

tr|T1G2V6|T1G2V6_HELRO
Uncharacterized protein
Search

0.85	Centromere protein S

0.79	GO:0051382	kinetochore assembly
0.62	GO:0006281	DNA repair
0.57	GO:0000712	resolution of meiotic recombination intermediates
0.55	GO:0031297	replication fork processing
0.49	GO:0006312	mitotic recombination
0.46	GO:0010469	regulation of receptor activity
0.41	GO:0019521	D-gluconate metabolic process
0.40	GO:0006098	pentose-phosphate shunt
0.38	GO:0051301	cell division
0.36	GO:0034080	CENP-A containing nucleosome assembly

0.74	GO:0046982	protein heterodimerization activity
0.52	GO:0003682	chromatin binding
0.50	GO:0003690	double-stranded DNA binding
0.47	GO:0005179	hormone activity
0.41	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity
0.35	GO:0016783	sulfurtransferase activity

0.85	GO:0071821	FANCM-MHF complex
0.74	GO:0000776	kinetochore
0.56	GO:0043240	Fanconi anaemia nuclear complex
0.43	GO:0005576	extracellular region
0.41	GO:0000779	condensed chromosome, centromeric region
0.34	GO:0031903	microbody membrane
0.34	GO:0044439	peroxisomal part
0.34	GO:0005829	cytosol

0.41

EC:1.1.1.44

GO:0004616

tr|T1G2V7|T1G2V7_HELRO
Uncharacterized protein
Search

CERS1

0.97	Ceramide synthase 1

0.52	GO:0046513	ceramide biosynthetic process
0.42	GO:0072721	cellular response to dithiothreitol
0.41	GO:0036146	cellular response to mycotoxin
0.40	GO:0071492	cellular response to UV-A
0.40	GO:0051974	negative regulation of telomerase activity
0.38	GO:0035690	cellular response to drug
0.38	GO:0007420	brain development
0.35	GO:0010469	regulation of receptor activity

0.54	GO:0050291	sphingosine N-acyltransferase activity
0.36	GO:0008083	growth factor activity
0.34	GO:0003677	DNA binding

0.46	GO:0005783	endoplasmic reticulum
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0005634	nucleus
0.35	GO:0031984	organelle subcompartment
0.34	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.54

EC:2.3.1.24

GO:0050291

tr|T1G2V8|T1G2V8_HELRO
Uncharacterized protein
Search

tr|T1G2V9|T1G2V9_HELRO
Uncharacterized protein
Search

0.54	GO:0018279	protein N-linked glycosylation via asparagine
0.50	GO:0050890	cognition
0.48	GO:1903830	magnesium ion transmembrane transport

0.48	GO:0015095	magnesium ion transmembrane transporter activity
0.47	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity
0.39	GO:0005102	receptor binding

0.53	GO:0008250	oligosaccharyltransferase complex
0.42	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.47

EC:2.4.1.119

GO:0004579

tr|T1G2W0|T1G2W0_HELRO
Uncharacterized protein
Search

tr|T1G2W1|T1G2W1_HELRO
Uncharacterized protein
Search

GST1

0.38	Glutathione S-transferase Ia

0.34	GO:0045087	innate immune response
0.34	GO:0006749	glutathione metabolic process
0.34	GO:0098869	cellular oxidant detoxification
0.33	GO:0055114	oxidation-reduction process

0.62	GO:0004364	glutathione transferase activity
0.36	GO:0005212	structural constituent of eye lens
0.35	GO:0004602	glutathione peroxidase activity
0.34	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.34	GO:0004497	monooxygenase activity
0.33	GO:0020037	heme binding
0.33	GO:0005506	iron ion binding

0.35	GO:0005903	brush border
0.35	GO:0043292	contractile fiber
0.30	GO:0044425	membrane part

0.62

EC:2.5.1.18

GO:0004364

tr|T1G2W2|T1G2W2_HELRO
Uncharacterized protein
Search

0.54	Microfibril associated protein 4

0.48	GO:0030199	collagen fibril organization
0.46	GO:0007155	cell adhesion
0.45	GO:0042127	regulation of cell proliferation
0.43	GO:1905240	negative regulation of canonical Wnt signaling pathway involved in osteoblast differentiation
0.42	GO:0001867	complement activation, lectin pathway
0.42	GO:0002076	osteoblast development
0.42	GO:0048699	generation of neurons
0.40	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.40	GO:0000904	cell morphogenesis involved in differentiation
0.39	GO:0120036	plasma membrane bounded cell projection organization

0.43	GO:0033691	sialic acid binding
0.41	GO:0005178	integrin binding
0.40	GO:0090729	toxin activity
0.40	GO:0008061	chitin binding
0.39	GO:0042802	identical protein binding
0.38	GO:0030246	carbohydrate binding
0.38	GO:0046872	metal ion binding
0.35	GO:0016491	oxidoreductase activity
0.35	GO:0022857	transmembrane transporter activity
0.34	GO:0003676	nucleic acid binding

0.52	GO:0031012	extracellular matrix
0.42	GO:1990026	hippocampal mossy fiber expansion
0.42	GO:0097442	CA3 pyramidal cell dendrite
0.40	GO:0005581	collagen trimer
0.40	GO:0043025	neuronal cell body
0.39	GO:0009986	cell surface
0.30	GO:0016020	membrane

0.35

GO:0016491

tr|T1G2W3|T1G2W3_HELRO
Uncharacterized protein
Search

KAT2A

0.84	Lysine acetyltransferase 2A

0.78	GO:0016573	histone acetylation
0.71	GO:0035948	positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter
0.69	GO:0018335	protein succinylation
0.68	GO:0045589	regulation of regulatory T cell differentiation
0.68	GO:0046600	negative regulation of centriole replication
0.66	GO:0007616	long-term memory
0.66	GO:0030901	midbrain development
0.66	GO:1903146	regulation of autophagy of mitochondrion
0.65	GO:0001756	somitogenesis
0.65	GO:0001843	neural tube closure

0.80	GO:0004402	histone acetyltransferase activity
0.71	GO:0106075	peptide N-succinyltransferase activity
0.66	GO:0042826	histone deacetylase binding
0.62	GO:0003713	transcription coactivator activity
0.61	GO:0003682	chromatin binding
0.58	GO:0008134	transcription factor binding
0.42	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor
0.41	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity
0.40	GO:0019901	protein kinase binding
0.39	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding

0.67	GO:0030914	STAGA complex
0.67	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex
0.67	GO:0033276	transcription factor TFTC complex
0.62	GO:0072686	mitotic spindle
0.61	GO:0005813	centrosome
0.61	GO:0045252	oxoglutarate dehydrogenase complex
0.41	GO:0031672	A band
0.41	GO:0042641	actomyosin
0.41	GO:0031674	I band
0.40	GO:0000776	kinetochore

0.80

GO:0004402

tr|T1G2W4|T1G2W4_HELRO
Guanylate cyclase
Search

0.45	Guanylate cyclase

0.81	GO:0006182	cGMP biosynthetic process
0.62	GO:0006468	protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.46	GO:0060038	cardiac muscle cell proliferation
0.38	GO:0007168	receptor guanylyl cyclase signaling pathway
0.38	GO:0018212	peptidyl-tyrosine modification
0.35	GO:0042127	regulation of cell proliferation
0.35	GO:0045792	negative regulation of cell size
0.34	GO:0007030	Golgi organization
0.34	GO:0045931	positive regulation of mitotic cell cycle

0.81	GO:0004383	guanylate cyclase activity
0.63	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0004016	adenylate cyclase activity
0.38	GO:0016941	natriuretic peptide receptor activity
0.34	GO:0005272	sodium channel activity
0.33	GO:0004930	G-protein coupled receptor activity
0.33	GO:0051287	NAD binding

0.45	GO:0005622	intracellular
0.37	GO:0043234	protein complex
0.36	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.81

GO:0004383

tr|T1G2W5|T1G2W5_HELRO
Uncharacterized protein
Search

PRPF6

0.80	Pre-mRNA-processing factor 6

0.75	GO:0000398	mRNA splicing, via spliceosome
0.48	GO:0022618	ribonucleoprotein complex assembly
0.47	GO:0045944	positive regulation of transcription by RNA polymerase II
0.46	GO:0006403	RNA localization

0.52	GO:0050681	androgen receptor binding
0.48	GO:0003713	transcription coactivator activity
0.46	GO:0043021	ribonucleoprotein complex binding
0.41	GO:0003723	RNA binding

0.61	GO:0005634	nucleus
0.50	GO:0120114	Sm-like protein family complex
0.44	GO:0031974	membrane-enclosed lumen
0.43	GO:1902494	catalytic complex
0.43	GO:0030529	intracellular ribonucleoprotein complex
0.41	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

tr|T1G2W6|T1G2W6_HELRO
Cytochrome b-c1 complex subunit Rieske, mitochondrial
Search

0.68	Cytochrome b-c1 complex subunit Rieske, mitochondrial

0.59	GO:0022900	electron transport chain
0.43	GO:0006119	oxidative phosphorylation
0.42	GO:0009060	aerobic respiration

0.71	GO:0016681	oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor
0.68	GO:0051537	2 iron, 2 sulfur cluster binding
0.60	GO:0009055	electron transfer activity
0.32	GO:0046872	metal ion binding

0.57	GO:0070469	respiratory chain
0.57	GO:0031966	mitochondrial membrane
0.57	GO:0019866	organelle inner membrane
0.47	GO:0098798	mitochondrial protein complex
0.45	GO:0070069	cytochrome complex
0.45	GO:1990204	oxidoreductase complex
0.42	GO:0098796	membrane protein complex
0.30	GO:0031224	intrinsic component of membrane

0.71

EC:1.10.2

GO:0016681

tr|T1G2W7|T1G2W7_HELRO
Guanylate cyclase
Search

0.47	Guanylate cyclase

0.80	GO:0006182	cGMP biosynthetic process
0.62	GO:0006468	protein phosphorylation
0.61	GO:0035556	intracellular signal transduction
0.45	GO:0060038	cardiac muscle cell proliferation
0.37	GO:0007168	receptor guanylyl cyclase signaling pathway
0.35	GO:0018212	peptidyl-tyrosine modification
0.34	GO:0042127	regulation of cell proliferation
0.33	GO:0035725	sodium ion transmembrane transport
0.33	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:0009636	response to toxic substance

0.80	GO:0004383	guanylate cyclase activity
0.62	GO:0004672	protein kinase activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0004016	adenylate cyclase activity
0.37	GO:0016941	natriuretic peptide receptor activity
0.34	GO:0005272	sodium channel activity
0.33	GO:0004930	G-protein coupled receptor activity
0.33	GO:0051287	NAD binding

0.44	GO:0005622	intracellular
0.37	GO:0043234	protein complex
0.36	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.80

GO:0004383

tr|T1G2W8|T1G2W8_HELRO
Uncharacterized protein
Search

PLEKHF2

0.87	Pleckstrin homology and FYVE domain containing 2

0.41	GO:0008333	endosome to lysosome transport
0.40	GO:0007032	endosome organization
0.38	GO:0006897	endocytosis
0.34	GO:0015031	protein transport
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process

0.54	GO:0046872	metal ion binding
0.39	GO:0035091	phosphatidylinositol binding
0.34	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
0.33	GO:0005515	protein binding
0.33	GO:0003735	structural constituent of ribosome

0.47	GO:0030133	transport vesicle
0.41	GO:0005769	early endosome
0.40	GO:0005770	late endosome
0.36	GO:0010008	endosome membrane
0.34	GO:0005783	endoplasmic reticulum
0.34	GO:0016324	apical plasma membrane
0.34	GO:0005938	cell cortex
0.33	GO:0015934	large ribosomal subunit
0.30	GO:0016021	integral component of membrane

0.34	EC:3.2.1.113	GO:0004571
0.34	KEGG:R05982 KEGG:R06722	GO:0004571

tr|T1G2W9|T1G2W9_HELRO
Guanylate cyclase
Search

0.46	Guanylate cyclase

0.81	GO:0006182	cGMP biosynthetic process
0.62	GO:0006468	protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.45	GO:0060038	cardiac muscle cell proliferation
0.39	GO:0007168	receptor guanylyl cyclase signaling pathway
0.35	GO:1900194	negative regulation of oocyte maturation
0.35	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus
0.34	GO:0051447	negative regulation of meiotic cell cycle
0.34	GO:0060348	bone development
0.33	GO:0042127	regulation of cell proliferation

0.81	GO:0004383	guanylate cyclase activity
0.63	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0004016	adenylate cyclase activity
0.39	GO:0016941	natriuretic peptide receptor activity
0.34	GO:0017046	peptide hormone binding
0.34	GO:0005272	sodium channel activity
0.33	GO:0042802	identical protein binding

0.45	GO:0005622	intracellular
0.37	GO:0043234	protein complex
0.36	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.81

GO:0004383

tr|T1G2X0|T1G2X0_HELRO
Uncharacterized protein
Search

0.48	GO:0007017	microtubule-based process
0.44	GO:0097435	supramolecular fiber organization
0.43	GO:0007010	cytoskeleton organization
0.42	GO:0035335	peptidyl-tyrosine dephosphorylation
0.42	GO:0006928	movement of cell or subcellular component
0.39	GO:0016255	attachment of GPI anchor to protein
0.39	GO:0006351	transcription, DNA-templated
0.38	GO:0009793	embryo development ending in seed dormancy
0.38	GO:1903506	regulation of nucleic acid-templated transcription
0.38	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.69	GO:0051010	microtubule plus-end binding
0.43	GO:0003777	microtubule motor activity
0.43	GO:0004725	protein tyrosine phosphatase activity
0.38	GO:0004806	triglyceride lipase activity
0.38	GO:0003676	nucleic acid binding
0.38	GO:0008270	zinc ion binding
0.37	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding

0.70	GO:0035371	microtubule plus-end
0.68	GO:0005881	cytoplasmic microtubule
0.40	GO:0043231	intracellular membrane-bounded organelle
0.37	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.37	GO:0031984	organelle subcompartment
0.36	GO:1902494	catalytic complex
0.30	GO:0031224	intrinsic component of membrane

0.43

GO:0004725

tr|T1G2X1|T1G2X1_HELRO
Uncharacterized protein
Search

XDH

0.49	Molybdopterin-binding domain of aldehyde dehydrogenase

0.58	GO:0022900	electron transport chain
0.53	GO:0009115	xanthine catabolic process
0.49	GO:2001213	negative regulation of vasculogenesis
0.48	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway
0.47	GO:0045602	negative regulation of endothelial cell differentiation
0.47	GO:1900745	positive regulation of p38MAPK cascade
0.46	GO:0001937	negative regulation of endothelial cell proliferation
0.46	GO:0051898	negative regulation of protein kinase B signaling
0.46	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.46	GO:2000379	positive regulation of reactive oxygen species metabolic process

0.75	GO:0004855	xanthine oxidase activity
0.74	GO:0004854	xanthine dehydrogenase activity
0.69	GO:0051537	2 iron, 2 sulfur cluster binding
0.66	GO:0043546	molybdopterin cofactor binding
0.65	GO:0050660	flavin adenine dinucleotide binding
0.64	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors
0.62	GO:0005506	iron ion binding
0.59	GO:0009055	electron transfer activity
0.48	GO:0030151	molybdenum ion binding
0.43	GO:0042803	protein homodimerization activity

0.44	GO:0016529	sarcoplasmic reticulum
0.41	GO:0005829	cytosol
0.36	GO:0005777	peroxisome
0.36	GO:0005615	extracellular space
0.30	GO:0016020	membrane

0.75

EC:1.17.3.2

GO:0004855

tr|T1G2X2|T1G2X2_HELRO
Uncharacterized protein
Search

0.76	Phytanoyl-CoA hydroxylase-interacting protein (Fragment)

0.56

GO:0042450

arginine biosynthetic process via ornithine

0.57	GO:0004056	argininosuccinate lyase activity
0.50	GO:0008270	zinc ion binding
0.49	GO:0005515	protein binding

0.39

GO:0005622

intracellular

0.57

EC:4.3.2.1

GO:0004056

tr|T1G2X3|T1G2X3_HELRO
Synaptotagmin 15a
Search

SYT15

0.89	Synaptotagmin-15 isoform C

0.49	GO:0006887	exocytosis
0.47	GO:0017158	regulation of calcium ion-dependent exocytosis
0.46	GO:0048489	synaptic vesicle transport
0.46	GO:0099504	synaptic vesicle cycle
0.46	GO:0006906	vesicle fusion
0.46	GO:0099643	signal release from synapse
0.46	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.44	GO:0006836	neurotransmitter transport
0.43	GO:0001505	regulation of neurotransmitter levels

0.50	GO:0005544	calcium-dependent phospholipid binding
0.46	GO:0019905	syntaxin binding
0.46	GO:0030276	clathrin binding
0.42	GO:0005509	calcium ion binding

0.47	GO:0019898	extrinsic component of membrane
0.45	GO:0098793	presynapse
0.38	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1G2X4|T1G2X4_HELRO
Uncharacterized protein
Search

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.46	GO:0007186	G-protein coupled receptor signaling pathway
0.45	GO:0007166	cell surface receptor signaling pathway
0.41	GO:0007275	multicellular organism development
0.39	GO:0120036	plasma membrane bounded cell projection organization
0.39	GO:0048468	cell development
0.38	GO:0009653	anatomical structure morphogenesis
0.37	GO:0001667	ameboidal-type cell migration
0.37	GO:0007267	cell-cell signaling
0.36	GO:0007605	sensory perception of sound

0.70	GO:0005509	calcium ion binding
0.46	GO:0004930	G-protein coupled receptor activity
0.35	GO:0005515	protein binding
0.33	GO:0008233	peptidase activity

0.56	GO:0005886	plasma membrane
0.37	GO:0032420	stereocilium
0.34	GO:0044291	cell-cell contact zone
0.34	GO:0030426	growth cone
0.34	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0008233

tr|T1G2X5|T1G2X5_HELRO
Uncharacterized protein
Search

0.93	Out at first, isoform B

0.45	GO:0016321	female meiosis chromosome segregation
0.44	GO:0007275	multicellular organism development

0.30

GO:0044425

membrane part

tr|T1G2X6|T1G2X6_HELRO
Guanylate cyclase
Search

0.44	Guanylate cyclase

0.80	GO:0006182	cGMP biosynthetic process
0.61	GO:0006468	protein phosphorylation
0.61	GO:0035556	intracellular signal transduction
0.44	GO:0060038	cardiac muscle cell proliferation
0.37	GO:0007168	receptor guanylyl cyclase signaling pathway
0.34	GO:0042127	regulation of cell proliferation
0.33	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:0018212	peptidyl-tyrosine modification
0.33	GO:0035725	sodium ion transmembrane transport
0.33	GO:0009636	response to toxic substance

0.80	GO:0004383	guanylate cyclase activity
0.62	GO:0004672	protein kinase activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0004016	adenylate cyclase activity
0.37	GO:0016941	natriuretic peptide receptor activity
0.34	GO:0005272	sodium channel activity
0.34	GO:0004930	G-protein coupled receptor activity
0.33	GO:0051287	NAD binding

0.44	GO:0005622	intracellular
0.37	GO:0043234	protein complex
0.36	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.80

GO:0004383

tr|T1G2X7|T1G2X7_HELRO
Uncharacterized protein
Search

0.10	UPF0420 protein C16orf58 (inferred by orthology to a human protein)

0.35	GO:0002532	production of molecular mediator involved in inflammatory response
0.34	GO:0010390	histone monoubiquitination
0.34	GO:0019221	cytokine-mediated signaling pathway

0.34	GO:0004896	cytokine receptor activity
0.34	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0003677	DNA binding

0.30

GO:0044425

membrane part

0.34

GO:0004842

tr|T1G2X8|T1G2X8_HELRO
Uncharacterized protein
Search

0.84	Homeotic protein even-skipped

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.48	GO:0021521	ventral spinal cord interneuron specification
0.45	GO:0009792	embryo development ending in birth or egg hatching
0.43	GO:1902680	positive regulation of RNA biosynthetic process
0.39	GO:0033334	fin morphogenesis
0.35	GO:0042661	regulation of mesodermal cell fate specification
0.35	GO:0036342	post-anal tail morphogenesis
0.34	GO:0043043	peptide biosynthetic process

0.64	GO:0043565	sequence-specific DNA binding
0.35	GO:0003700	DNA binding transcription factor activity
0.34	GO:0003735	structural constituent of ribosome
0.33	GO:0003723	RNA binding

0.61	GO:0005634	nucleus
0.41	GO:0031974	membrane-enclosed lumen
0.38	GO:0044446	intracellular organelle part
0.34	GO:0005840	ribosome
0.30	GO:0016020	membrane

tr|T1G2X9|T1G2X9_HELRO
Uncharacterized protein
Search

0.39	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit

0.45	GO:0015914	phospholipid transport
0.42	GO:0045947	negative regulation of translational initiation
0.41	GO:0055114	oxidation-reduction process
0.38	GO:0006119	oxidative phosphorylation

0.48	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.45	GO:0005548	phospholipid transporter activity
0.44	GO:0008190	eukaryotic initiation factor 4E binding
0.38	GO:0003676	nucleic acid binding

0.56	GO:0005747	mitochondrial respiratory chain complex I
0.47	GO:0005634	nucleus
0.41	GO:0000178	exosome (RNase complex)
0.38	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.48

GO:0008137

tr|T1G2Y1|T1G2Y1_HELRO
Uncharacterized protein
Search

tr|T1G2Y2|T1G2Y2_HELRO
Uncharacterized protein
Search

0.30

GO:0008152

metabolic process

0.63

GO:0016746

transferase activity, transferring acyl groups

0.30

GO:0044425

membrane part

0.63

EC:2.3

GO:0016746

tr|T1G2Y3|T1G2Y3_HELRO
Guanylate cyclase
Search

0.47	Guanylate cyclase

0.82	GO:0006182	cGMP biosynthetic process
0.63	GO:0035556	intracellular signal transduction
0.62	GO:0006468	protein phosphorylation
0.41	GO:0042127	regulation of cell proliferation
0.39	GO:0009636	response to toxic substance
0.38	GO:0060038	cardiac muscle cell proliferation
0.36	GO:0018212	peptidyl-tyrosine modification
0.33	GO:0006508	proteolysis

0.82	GO:0004383	guanylate cyclase activity
0.63	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0004016	adenylate cyclase activity
0.34	GO:0015643	toxic substance binding
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0019001	guanyl nucleotide binding
0.33	GO:0004222	metalloendopeptidase activity

0.47	GO:0008074	guanylate cyclase complex, soluble
0.38	GO:0005886	plasma membrane
0.34	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

0.82

GO:0004383

tr|T1G2Y4|T1G2Y4_HELRO
Guanylate cyclase
Search

0.44	Guanylate cyclase

0.81	GO:0006182	cGMP biosynthetic process
0.63	GO:0035556	intracellular signal transduction
0.61	GO:0006468	protein phosphorylation
0.44	GO:0060038	cardiac muscle cell proliferation
0.37	GO:0018212	peptidyl-tyrosine modification
0.37	GO:0007168	receptor guanylyl cyclase signaling pathway
0.35	GO:0042127	regulation of cell proliferation
0.34	GO:0045792	negative regulation of cell size
0.34	GO:0007030	Golgi organization
0.34	GO:0045931	positive regulation of mitotic cell cycle

0.82	GO:0004383	guanylate cyclase activity
0.62	GO:0004672	protein kinase activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0004016	adenylate cyclase activity
0.38	GO:0016941	natriuretic peptide receptor activity
0.33	GO:0005272	sodium channel activity
0.33	GO:0004930	G-protein coupled receptor activity
0.33	GO:0051287	NAD binding

0.45	GO:0005622	intracellular
0.37	GO:0043234	protein complex
0.36	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.82

GO:0004383

tr|T1G2Y5|T1G2Y5_HELRO
Uncharacterized protein
Search

tr|T1G2Y6|T1G2Y6_HELRO
Uncharacterized protein
Search

0.70	Heterogeneous nuclear ribonucleoprotein A/Bb

0.59

GO:0003723

RNA binding

0.68	GO:0019013	viral nucleocapsid
0.58	GO:0030529	intracellular ribonucleoprotein complex
0.35	GO:0005654	nucleoplasm

tr|T1G2Y7|T1G2Y7_HELRO
Uncharacterized protein
Search

CANT1

0.92	Soluble calcium-activated nucleotidase 1

0.56	GO:0030166	proteoglycan biosynthetic process
0.36	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.35	GO:0009191	ribonucleoside diphosphate catabolic process
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0007165	signal transduction

0.80	GO:0017110	nucleoside-diphosphatase activity
0.68	GO:0005509	calcium ion binding
0.50	GO:0042803	protein homodimerization activity
0.34	GO:0004871	signal transducer activity

0.37	GO:0032580	Golgi cisterna membrane
0.37	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0070062	extracellular exosome
0.36	GO:1904724	tertiary granule lumen
0.36	GO:0035580	specific granule lumen
0.35	GO:1904813	ficolin-1-rich granule lumen
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.80

EC:3.6.1.6

GO:0017110

tr|T1G2Y8|T1G2Y8_HELRO
Uncharacterized protein
Search

0.36	GO:0006357	regulation of transcription by RNA polymerase II
0.33	GO:0006468	protein phosphorylation
0.33	GO:0006508	proteolysis

0.68	GO:0046983	protein dimerization activity
0.47	GO:0003677	DNA binding
0.37	GO:0001067	regulatory region nucleic acid binding
0.35	GO:0003700	DNA binding transcription factor activity
0.33	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0017171	serine hydrolase activity
0.33	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.33	GO:0016301	kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding

0.39	GO:0005654	nucleoplasm
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0016773

tr|T1G2Y9|T1G2Y9_HELRO
Uncharacterized protein
Search

tr|T1G2Z0|T1G2Z0_HELRO
Uncharacterized protein
Search

0.57	Tumor suppressor candidate 3

0.46	GO:0018279	protein N-linked glycosylation via asparagine
0.44	GO:0035010	encapsulation of foreign target
0.41	GO:0016477	cell migration
0.41	GO:0050890	cognition
0.41	GO:0015693	magnesium ion transport
0.37	GO:0098662	inorganic cation transmembrane transport
0.33	GO:0010469	regulation of receptor activity

0.43	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity
0.40	GO:0015095	magnesium ion transmembrane transporter activity
0.34	GO:0008270	zinc ion binding
0.33	GO:0005179	hormone activity
0.33	GO:0000062	fatty-acyl-CoA binding
0.33	GO:0003676	nucleic acid binding

0.45	GO:0008250	oligosaccharyltransferase complex
0.37	GO:0005739	mitochondrion
0.33	GO:0005634	nucleus
0.33	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.43

EC:2.4.1.119

GO:0004579

tr|T1G2Z1|T1G2Z1_HELRO
Uncharacterized protein
Search

0.38	GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.37	GO:0000472	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.37	GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

0.50

GO:0016740

transferase activity

0.41	GO:0005730	nucleolus
0.30	GO:0031224	intrinsic component of membrane

0.50

GO:0016740

tr|T1G2Z2|T1G2Z2_HELRO
Uncharacterized protein
Search

ZNF706

0.95	Zinc finger protein 706

0.85	GO:1902455	negative regulation of stem cell population maintenance
0.67	GO:0045892	negative regulation of transcription, DNA-templated
0.46	GO:0006417	regulation of translation

0.39	GO:0046872	metal ion binding
0.38	GO:0019904	protein domain specific binding
0.37	GO:0003676	nucleic acid binding

0.58	GO:0005634	nucleus
0.47	GO:0005737	cytoplasm

tr|T1G2Z3|T1G2Z3_HELRO
Uncharacterized protein
Search

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.41	GO:0030154	cell differentiation
0.41	GO:0009653	anatomical structure morphogenesis
0.38	GO:1902680	positive regulation of RNA biosynthetic process
0.38	GO:0006366	transcription by RNA polymerase II
0.33	GO:1902679	negative regulation of RNA biosynthetic process

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.39	GO:0001012	RNA polymerase II regulatory region DNA binding
0.38	GO:0003690	double-stranded DNA binding
0.37	GO:0000287	magnesium ion binding

0.61	GO:0005634	nucleus
0.35	GO:0044599	AP-5 adaptor complex
0.30	GO:0016021	integral component of membrane

tr|T1G2Z4|T1G2Z4_HELRO
Uncharacterized protein
Search

0.59	GO:0006649	phospholipid transfer to membrane
0.59	GO:0007601	visual perception
0.56	GO:0045494	photoreceptor cell maintenance
0.55	GO:0055085	transmembrane transport
0.53	GO:0045332	phospholipid translocation
0.37	GO:0038027	apolipoprotein A-I-mediated signaling pathway
0.37	GO:0034380	high-density lipoprotein particle assembly
0.37	GO:0033700	phospholipid efflux
0.36	GO:0033344	cholesterol efflux
0.36	GO:0007603	phototransduction, visible light

0.66	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.60	GO:0090555	phosphatidylethanolamine-translocating ATPase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0090556	phosphatidylserine-translocating ATPase activity
0.37	GO:0034188	apolipoprotein A-I receptor activity
0.37	GO:0090554	phosphatidylcholine-translocating ATPase activity
0.35	GO:0019842	vitamin binding
0.34	GO:0050662	coenzyme binding

0.56	GO:0001750	photoreceptor outer segment
0.52	GO:0005887	integral component of plasma membrane
0.41	GO:0043227	membrane-bounded organelle
0.39	GO:0043229	intracellular organelle
0.38	GO:0031253	cell projection membrane
0.35	GO:0012505	endomembrane system
0.35	GO:0030054	cell junction
0.34	GO:0098805	whole membrane
0.34	GO:0042555	MCM complex
0.34	GO:0044444	cytoplasmic part

0.33

GO:0016705

tr|T1G2Z5|T1G2Z5_HELRO
Uncharacterized protein
Search

POP4

0.78	ribonuclease P protein subunit p29

0.81	GO:0006379	mRNA cleavage
0.68	GO:0006364	rRNA processing
0.66	GO:0008033	tRNA processing
0.55	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic

0.70	GO:0004540	ribonuclease activity
0.59	GO:0003723	RNA binding
0.55	GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
0.52	GO:0140101	catalytic activity, acting on a tRNA
0.34	GO:0005515	protein binding
0.32	GO:0046872	metal ion binding

0.84	GO:0000172	ribonuclease MRP complex
0.83	GO:0030681	multimeric ribonuclease P complex
0.76	GO:0044452	nucleolar part
0.34	GO:0005654	nucleoplasm

0.55

EC:3.1.30

GO:0016893

tr|T1G2Z6|T1G2Z6_HELRO
Uncharacterized protein
Search

0.57	Atrial natriuretic peptide receptor 2 (Fragment)

0.81	GO:0006182	cGMP biosynthetic process
0.63	GO:0035556	intracellular signal transduction
0.57	GO:0006468	protein phosphorylation
0.43	GO:0060038	cardiac muscle cell proliferation
0.36	GO:0007168	receptor guanylyl cyclase signaling pathway
0.33	GO:0018212	peptidyl-tyrosine modification
0.33	GO:0007186	G-protein coupled receptor signaling pathway
0.32	GO:0055114	oxidation-reduction process

0.81	GO:0004383	guanylate cyclase activity
0.57	GO:0004672	protein kinase activity
0.52	GO:1901265	nucleoside phosphate binding
0.51	GO:0036094	small molecule binding
0.49	GO:0097367	carbohydrate derivative binding
0.49	GO:0008144	drug binding
0.48	GO:0043168	anion binding
0.42	GO:0004016	adenylate cyclase activity
0.37	GO:0016941	natriuretic peptide receptor activity
0.35	GO:0020037	heme binding

0.45	GO:0005622	intracellular
0.37	GO:0043234	protein complex
0.36	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.81

GO:0004383

tr|T1G2Z7|T1G2Z7_HELRO
Palmitoyltransferase
Search

ZDHHC3

0.54	Palmitoyltransferase

0.48	GO:0018345	protein palmitoylation
0.43	GO:0046854	phosphatidylinositol phosphorylation
0.42	GO:0006605	protein targeting
0.36	GO:0018231	peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine

0.79

GO:0019706

protein-cysteine S-palmitoyltransferase activity

0.46	GO:0005794	Golgi apparatus
0.34	GO:0098588	bounding membrane of organelle
0.34	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.79

GO:0019706

tr|T1G2Z8|T1G2Z8_HELRO
Guanylate cyclase
Search

0.45	Guanylate cyclase

0.82	GO:0006182	cGMP biosynthetic process
0.63	GO:0035556	intracellular signal transduction
0.59	GO:0006468	protein phosphorylation
0.44	GO:0060038	cardiac muscle cell proliferation
0.37	GO:0007168	receptor guanylyl cyclase signaling pathway
0.34	GO:0007186	G-protein coupled receptor signaling pathway
0.34	GO:0018212	peptidyl-tyrosine modification

0.82	GO:0004383	guanylate cyclase activity
0.60	GO:0004672	protein kinase activity
0.53	GO:1901265	nucleoside phosphate binding
0.51	GO:0097367	carbohydrate derivative binding
0.51	GO:0008144	drug binding
0.51	GO:0036094	small molecule binding
0.50	GO:0043168	anion binding
0.42	GO:0004016	adenylate cyclase activity
0.37	GO:0016941	natriuretic peptide receptor activity
0.34	GO:0004930	G-protein coupled receptor activity

0.45	GO:0005622	intracellular
0.37	GO:0043234	protein complex
0.36	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.82

GO:0004383

tr|T1G2Z9|T1G2Z9_HELRO
Uncharacterized protein
Search

0.60	Glucose-dependent insulinotropic receptor

0.36	GO:0070647	protein modification by small protein conjugation or removal
0.34	GO:0042073	intraciliary transport
0.34	GO:0006508	proteolysis
0.33	GO:0060271	cilium assembly
0.33	GO:0006351	transcription, DNA-templated
0.33	GO:0006313	transposition, DNA-mediated
0.33	GO:0015074	DNA integration
0.33	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.33	GO:0007186	G-protein coupled receptor signaling pathway
0.32	GO:0006355	regulation of transcription, DNA-templated

0.35	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.34	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0031683	G-protein beta/gamma-subunit complex binding
0.33	GO:0043565	sequence-specific DNA binding
0.33	GO:0015631	tubulin binding
0.33	GO:0008270	zinc ion binding
0.33	GO:0003700	DNA binding transcription factor activity
0.33	GO:0004636	phosphoribosyl-ATP diphosphatase activity
0.33	GO:0036094	small molecule binding
0.33	GO:1901265	nucleoside phosphate binding

0.34	GO:0030992	intraciliary transport particle B
0.33	GO:0031514	motile cilium
0.33	GO:0030008	TRAPP complex
0.33	GO:0043231	intracellular membrane-bounded organelle
0.32	GO:0044444	cytoplasmic part
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.33	EC:3.6.1.31	GO:0004636
0.34	KEGG:R03876	GO:0004842

tr|T1G300|T1G300_HELRO
Uncharacterized protein
Search

CHAF1B

0.89	LOW QUALITY PROTEIN: chromatin assembly factor 1 subunit B

0.84	GO:0006335	DNA replication-dependent nucleosome assembly
0.49	GO:0060041	retina development in camera-type eye
0.48	GO:0048568	embryonic organ development
0.46	GO:0007049	cell cycle
0.40	GO:0006260	DNA replication
0.39	GO:0006281	DNA repair
0.38	GO:0006351	transcription, DNA-templated
0.37	GO:1903506	regulation of nucleic acid-templated transcription
0.37	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.37	GO:0010468	regulation of gene expression

0.59	GO:0042393	histone binding
0.38	GO:0003682	chromatin binding
0.37	GO:0051082	unfolded protein binding
0.34	GO:0008270	zinc ion binding

0.85	GO:0033186	CAF-1 complex
0.70	GO:0000790	nuclear chromatin
0.66	GO:0005654	nucleoplasm
0.39	GO:0005829	cytosol

tr|T1G301|T1G301_HELRO
Uncharacterized protein
Search

0.41	GO:0034453	microtubule anchoring
0.40	GO:1903690	negative regulation of wound healing, spreading of epidermal cells
0.40	GO:1904259	regulation of basement membrane assembly involved in embryonic body morphogenesis
0.40	GO:0090091	positive regulation of extracellular matrix disassembly
0.40	GO:0031023	microtubule organizing center organization
0.40	GO:1901203	positive regulation of extracellular matrix assembly
0.40	GO:0007020	microtubule nucleation
0.40	GO:0030953	astral microtubule organization
0.40	GO:0051497	negative regulation of stress fiber assembly
0.40	GO:0010458	exit from mitosis

0.83	GO:0043515	kinetochore binding
0.81	GO:0051010	microtubule plus-end binding
0.39	GO:0002162	dystroglycan binding

0.81	GO:0005828	kinetochore microtubule
0.79	GO:0005881	cytoplasmic microtubule
0.41	GO:0031592	centrosomal corona
0.40	GO:0045180	basal cortex
0.40	GO:0030981	cortical microtubule cytoskeleton
0.39	GO:0000776	kinetochore
0.38	GO:0005925	focal adhesion
0.38	GO:0005794	Golgi apparatus
0.35	GO:0000779	condensed chromosome, centromeric region

tr|T1G302|T1G302_HELRO
Uncharacterized protein
Search

METTL15

0.69	Putative S-adenosyl-L-methionine-dependent methyltransferase

0.63	GO:0032259	methylation
0.55	GO:0000154	rRNA modification
0.41	GO:0044260	cellular macromolecule metabolic process
0.33	GO:0016311	dephosphorylation
0.33	GO:0055114	oxidation-reduction process
0.32	GO:0036211	protein modification process

0.63	GO:0008168	methyltransferase activity
0.55	GO:0140102	catalytic activity, acting on a rRNA
0.34	GO:0004329	formate-tetrahydrofolate ligase activity
0.34	GO:0004488	methylenetetrahydrofolate dehydrogenase (NADP+) activity
0.34	GO:0004725	protein tyrosine phosphatase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.41	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.63	EC:2.1.1	GO:0008168
0.34	KEGG:R01220	GO:0004488

tr|T1G303|T1G303_HELRO
Uncharacterized protein
Search

0.72	Calcium and integrin binding protein CIB

0.63	GO:0007229	integrin-mediated signaling pathway
0.49	GO:0106058	positive regulation of calcineurin-mediated signaling
0.49	GO:2000256	positive regulation of male germ cell proliferation
0.49	GO:0007113	endomitotic cell cycle
0.49	GO:0070884	regulation of calcineurin-NFAT signaling cascade
0.48	GO:0038163	thrombopoietin-mediated signaling pathway
0.48	GO:0045653	negative regulation of megakaryocyte differentiation
0.48	GO:0033630	positive regulation of cell adhesion mediated by integrin
0.48	GO:1990090	cellular response to nerve growth factor stimulus
0.48	GO:0090314	positive regulation of protein targeting to membrane

0.70	GO:0005509	calcium ion binding
0.49	GO:0008427	calcium-dependent protein kinase inhibitor activity
0.48	GO:0043495	protein membrane anchor
0.46	GO:0030291	protein serine/threonine kinase inhibitor activity
0.46	GO:0044325	ion channel binding
0.44	GO:0017016	Ras GTPase binding
0.38	GO:0016301	kinase activity
0.35	GO:0008022	protein C-terminus binding
0.35	GO:0019901	protein kinase binding
0.32	GO:0051015	actin filament binding

0.48	GO:0032433	filopodium tip
0.47	GO:0042383	sarcolemma
0.47	GO:0030426	growth cone
0.46	GO:0030027	lamellipodium
0.45	GO:0043025	neuronal cell body
0.45	GO:0048471	perinuclear region of cytoplasm
0.45	GO:0005813	centrosome
0.42	GO:0005654	nucleoplasm
0.42	GO:0005783	endoplasmic reticulum
0.38	GO:0032587	ruffle membrane

tr|T1G304|T1G304_HELRO
Uncharacterized protein
Search

0.49	GO:0036211	protein modification process
0.46	GO:0044267	cellular protein metabolic process
0.45	GO:0016310	phosphorylation
0.45	GO:0007165	signal transduction
0.44	GO:0070941	eisosome assembly
0.42	GO:0034220	ion transmembrane transport
0.40	GO:0016192	vesicle-mediated transport

0.49	GO:0004672	protein kinase activity
0.45	GO:0005216	ion channel activity
0.44	GO:0031625	ubiquitin protein ligase binding
0.44	GO:0032559	adenyl ribonucleotide binding
0.43	GO:0008144	drug binding
0.43	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0004842	ubiquitin-protein transferase activity

0.43	GO:0000151	ubiquitin ligase complex
0.43	GO:0032126	eisosome
0.43	GO:0030008	TRAPP complex
0.39	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.43

GO:0004842

tr|T1G305|T1G305_HELRO
Uncharacterized protein
Search

CTDSP1

0.91	Carboxy-terminal domain RNA polymerase II polypeptide A small

0.68	GO:0016311	dephosphorylation
0.57	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle
0.52	GO:0001933	negative regulation of protein phosphorylation
0.49	GO:0045665	negative regulation of neuron differentiation
0.46	GO:0036211	protein modification process
0.44	GO:0006357	regulation of transcription by RNA polymerase II
0.43	GO:0044267	cellular protein metabolic process
0.37	GO:0046662	regulation of oviposition
0.36	GO:0030182	neuron differentiation
0.35	GO:0036498	IRE1-mediated unfolded protein response

0.69	GO:0016791	phosphatase activity
0.44	GO:0140096	catalytic activity, acting on a protein
0.37	GO:0030274	LIM domain binding
0.36	GO:0030674	protein binding, bridging
0.36	GO:0019900	kinase binding
0.34	GO:0046872	metal ion binding
0.34	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.33	GO:0051015	actin filament binding
0.33	GO:0046873	metal ion transmembrane transporter activity

0.45	GO:0005654	nucleoplasm
0.37	GO:0031430	M band
0.36	GO:0031674	I band
0.35	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.69

EC:3.1.3 EC:3.1.3.41

GO:0016791

tr|T1G306|T1G306_HELRO
Guanylate cyclase
Search

0.47	Guanylate cyclase

0.80	GO:0006182	cGMP biosynthetic process
0.62	GO:0006468	protein phosphorylation
0.61	GO:0035556	intracellular signal transduction
0.45	GO:0060038	cardiac muscle cell proliferation
0.38	GO:0007168	receptor guanylyl cyclase signaling pathway
0.35	GO:1900194	negative regulation of oocyte maturation
0.35	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus
0.34	GO:0051447	negative regulation of meiotic cell cycle
0.34	GO:0060348	bone development
0.33	GO:0042127	regulation of cell proliferation

0.81	GO:0004383	guanylate cyclase activity
0.62	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0004016	adenylate cyclase activity
0.38	GO:0016941	natriuretic peptide receptor activity
0.34	GO:0017046	peptide hormone binding
0.34	GO:0005272	sodium channel activity
0.34	GO:0042802	identical protein binding

0.44	GO:0005622	intracellular
0.37	GO:0043234	protein complex
0.36	GO:0005886	plasma membrane
0.33	GO:0099512	supramolecular fiber
0.32	GO:0043228	non-membrane-bounded organelle
0.32	GO:0044422	organelle part
0.30	GO:0016021	integral component of membrane

0.81

GO:0004383

tr|T1G307|T1G307_HELRO
Uncharacterized protein
Search

tr|T1G308|T1G308_HELRO
Uncharacterized protein
Search

0.40	Ubiquitin carboxyl-terminal hydrolase (Fragment)

0.76	GO:0016579	protein deubiquitination
0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.62	GO:0051289	protein homotetramerization
0.58	GO:0016570	histone modification
0.58	GO:0140014	mitotic nuclear division
0.57	GO:0051726	regulation of cell cycle
0.56	GO:0045893	positive regulation of transcription, DNA-templated
0.52	GO:0051301	cell division
0.50	GO:0045901	positive regulation of translational elongation
0.47	GO:0006974	cellular response to DNA damage stimulus

0.77	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.60	GO:0043130	ubiquitin binding
0.60	GO:0008270	zinc ion binding
0.59	GO:0042393	histone binding
0.59	GO:0003713	transcription coactivator activity
0.57	GO:0004197	cysteine-type endopeptidase activity

0.51	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part

0.77

GO:0036459

tr|T1G309|T1G309_HELRO
Uncharacterized protein
Search

0.80	V-rel avian reticuloendotheliosis viral oncogene homolog A

0.64	GO:0006357	regulation of transcription by RNA polymerase II
0.57	GO:0007165	signal transduction
0.52	GO:0045083	negative regulation of interleukin-12 biosynthetic process
0.52	GO:0010956	negative regulation of calcidiol 1-monooxygenase activity
0.52	GO:1900127	positive regulation of hyaluronan biosynthetic process
0.52	GO:0071316	cellular response to nicotine
0.51	GO:2000630	positive regulation of miRNA metabolic process
0.50	GO:0071354	cellular response to interleukin-6
0.50	GO:0035994	response to muscle stretch
0.50	GO:1904385	cellular response to angiotensin

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.50	GO:0001067	regulatory region nucleic acid binding
0.49	GO:0003682	chromatin binding
0.48	GO:0042805	actinin binding
0.45	GO:0042803	protein homodimerization activity
0.45	GO:0046982	protein heterodimerization activity
0.45	GO:0008134	transcription factor binding

0.61	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.48	GO:0033256	I-kappaB/NF-kappaB complex
0.43	GO:0070013	intracellular organelle lumen
0.40	GO:0044446	intracellular organelle part
0.34	GO:0071159	NF-kappaB complex
0.34	GO:0031983	vesicle lumen
0.33	GO:0097708	intracellular vesicle
0.33	GO:0012505	endomembrane system
0.33	GO:0005576	extracellular region

tr|T1G310|T1G310_HELRO
Uncharacterized protein
Search

tr|T1G311|T1G311_HELRO
Guanylate cyclase
Search

0.45	Guanylate cyclase

0.81	GO:0006182	cGMP biosynthetic process
0.63	GO:0035556	intracellular signal transduction
0.60	GO:0006468	protein phosphorylation
0.39	GO:0060038	cardiac muscle cell proliferation
0.38	GO:0042127	regulation of cell proliferation
0.37	GO:0035845	photoreceptor cell outer segment organization
0.37	GO:0007601	visual perception
0.36	GO:0007168	receptor guanylyl cyclase signaling pathway
0.36	GO:0009636	response to toxic substance
0.36	GO:0018212	peptidyl-tyrosine modification

0.82	GO:0004383	guanylate cyclase activity
0.61	GO:0004672	protein kinase activity
0.52	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0004016	adenylate cyclase activity
0.37	GO:0016941	natriuretic peptide receptor activity
0.36	GO:0020037	heme binding
0.34	GO:0017046	peptide hormone binding
0.34	GO:0005515	protein binding

0.45	GO:0005622	intracellular
0.37	GO:0043234	protein complex
0.36	GO:0005886	plasma membrane
0.34	GO:0009986	cell surface
0.34	GO:0098552	side of membrane
0.30	GO:0016021	integral component of membrane

0.82

GO:0004383

tr|T1G312|T1G312_HELRO
Structure-specific endonuclease subunit SLX1 homolog
Search

0.76	Structure-specific endonuclease subunit SLX1

0.63	GO:0006310	DNA recombination
0.63	GO:0006281	DNA repair
0.62	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.50	GO:1904431	positive regulation of t-circle formation
0.50	GO:0001325	formation of extrachromosomal circular DNA
0.50	GO:0090737	telomere maintenance via telomere trimming
0.35	GO:0061820	telomeric D-loop disassembly
0.35	GO:1904357	negative regulation of telomere maintenance via telomere lengthening
0.35	GO:0010833	telomere maintenance via telomere lengthening

0.79	GO:0017108	5'-flap endonuclease activity
0.50	GO:0008821	crossover junction endodeoxyribonuclease activity
0.42	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding

0.82	GO:0033557	Slx1-Slx4 complex
0.33	GO:0005654	nucleoplasm

0.50

EC:3.1.22.4

GO:0008821

tr|T1G313|T1G313_HELRO
Guanylate cyclase
Search

0.46	Guanylate cyclase

0.81	GO:0006182	cGMP biosynthetic process
0.63	GO:0035556	intracellular signal transduction
0.60	GO:0006468	protein phosphorylation
0.41	GO:0060038	cardiac muscle cell proliferation
0.40	GO:0007168	receptor guanylyl cyclase signaling pathway
0.38	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus
0.38	GO:1900194	negative regulation of oocyte maturation
0.37	GO:0051447	negative regulation of meiotic cell cycle
0.37	GO:0060348	bone development
0.36	GO:0042127	regulation of cell proliferation

0.81	GO:0004383	guanylate cyclase activity
0.61	GO:0004672	protein kinase activity
0.52	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0004016	adenylate cyclase activity
0.41	GO:0016941	natriuretic peptide receptor activity
0.38	GO:0017046	peptide hormone binding
0.36	GO:0042802	identical protein binding
0.35	GO:0020037	heme binding

0.45	GO:0005622	intracellular
0.37	GO:0043234	protein complex
0.37	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.81

GO:0004383

tr|T1G314|T1G314_HELRO
Uncharacterized protein
Search

SLC30A2

0.72	Cation efflux protein/ zinc transporter

0.61	GO:0098655	cation transmembrane transport
0.55	GO:0006829	zinc II ion transport
0.52	GO:0006882	cellular zinc ion homeostasis
0.50	GO:0061088	regulation of sequestering of zinc ion
0.49	GO:0010043	response to zinc ion
0.46	GO:0098660	inorganic ion transmembrane transport
0.45	GO:0030073	insulin secretion
0.44	GO:0051238	sequestering of metal ion
0.44	GO:0009749	response to glucose
0.41	GO:0032846	positive regulation of homeostatic process

0.61	GO:0008324	cation transmembrane transporter activity
0.45	GO:0015318	inorganic molecular entity transmembrane transporter activity
0.41	GO:0042803	protein homodimerization activity
0.34	GO:0008270	zinc ion binding
0.34	GO:0004862	cAMP-dependent protein kinase inhibitor activity
0.34	GO:0030246	carbohydrate binding
0.33	GO:0015267	channel activity

0.48	GO:0031410	cytoplasmic vesicle
0.43	GO:0012505	endomembrane system
0.38	GO:0005886	plasma membrane
0.38	GO:0031090	organelle membrane
0.37	GO:0044446	intracellular organelle part
0.36	GO:0098805	whole membrane
0.36	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

tr|T1G315|T1G315_HELRO
Uncharacterized protein
Search

MSH4

0.61	MutS homolog 4 variant alpha

0.73	GO:0006298	mismatch repair
0.53	GO:0007129	synapsis
0.53	GO:0001541	ovarian follicle development
0.51	GO:0007292	female gamete generation
0.51	GO:0007283	spermatogenesis
0.44	GO:0007131	reciprocal meiotic recombination
0.39	GO:0022607	cellular component assembly
0.33	GO:0018344	protein geranylgeranylation
0.32	GO:0055114	oxidation-reduction process

0.74	GO:0030983	mismatched DNA binding
0.55	GO:0003684	damaged DNA binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0008094	DNA-dependent ATPase activity
0.33	GO:0004663	Rab geranylgeranyltransferase activity
0.33	GO:0005515	protein binding
0.33	GO:0003995	acyl-CoA dehydrogenase activity
0.32	GO:0050660	flavin adenine dinucleotide binding

0.56	GO:0005713	recombination nodule
0.54	GO:0000795	synaptonemal complex
0.52	GO:0032300	mismatch repair complex
0.34	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

0.33

EC:2.5.1.60

GO:0004663

tr|T1G316|T1G316_HELRO
Uncharacterized protein
Search

RPF2

0.85	Brix domain-containing protein 1

0.77	GO:1902570	protein localization to nucleolus
0.72	GO:1901796	regulation of signal transduction by p53 class mediator
0.72	GO:0042273	ribosomal large subunit biogenesis
0.60	GO:0042255	ribosome assembly
0.56	GO:0006364	rRNA processing
0.46	GO:0090307	mitotic spindle assembly
0.46	GO:1902626	assembly of large subunit precursor of preribosome
0.42	GO:0006438	valyl-tRNA aminoacylation
0.41	GO:0106074	aminoacyl-tRNA metabolism involved in translational fidelity
0.35	GO:0017062	respiratory chain complex III assembly

0.69	GO:0008097	5S rRNA binding
0.43	GO:0008312	7S RNA binding
0.42	GO:0004832	valine-tRNA ligase activity
0.41	GO:0002161	aminoacyl-tRNA editing activity
0.37	GO:0030554	adenyl nucleotide binding
0.36	GO:0032555	purine ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding

0.71	GO:0005730	nucleolus
0.34	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.42	EC:6.1.1.9	GO:0004832
0.42	KEGG:R03665	GO:0004832

tr|T1G317|T1G317_HELRO
Molybdenum cofactor sulfurase
Search

0.39	Molybdenum cofactor sulfurase

0.69	GO:0006777	Mo-molybdopterin cofactor biosynthetic process
0.35	GO:0018315	molybdenum incorporation into molybdenum-molybdopterin complex
0.34	GO:0045037	protein import into chloroplast stroma
0.34	GO:0043289	apocarotenoid biosynthetic process
0.34	GO:1902645	tertiary alcohol biosynthetic process
0.34	GO:0009687	abscisic acid metabolic process
0.34	GO:0010118	stomatal movement
0.34	GO:0010182	sugar mediated signaling pathway
0.34	GO:0016106	sesquiterpenoid biosynthetic process
0.34	GO:0032324	molybdopterin cofactor biosynthetic process

0.83	GO:0008265	Mo-molybdopterin cofactor sulfurase activity
0.78	GO:0102867	molybdenum cofactor sulfurtransferase activity
0.72	GO:0030151	molybdenum ion binding
0.64	GO:0030170	pyridoxal phosphate binding
0.56	GO:0016829	lyase activity
0.33	GO:0005515	protein binding
0.33	GO:0008483	transaminase activity
0.33	GO:0008270	zinc ion binding

0.33	GO:0005829	cytosol
0.33	GO:0033588	Elongator holoenzyme complex
0.32	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.78

EC:2.8.1.9

GO:0102867

tr|T1G318|T1G318_HELRO
Uncharacterized protein
Search

0.66	GO:0018344	protein geranylgeranylation
0.38	GO:0016310	phosphorylation

0.66	GO:0008318	protein prenyltransferase activity
0.58	GO:0005509	calcium ion binding
0.39	GO:0016301	kinase activity

0.67

GO:0005968

Rab-protein geranylgeranyltransferase complex

0.66

EC:2.5.1

GO:0008318

tr|T1G319|T1G319_HELRO
Uncharacterized protein
Search

0.52	Tyrosine sulfotransferase culex quinquefasciatus tyrosine sulfotransferase

0.84	GO:0006478	peptidyl-tyrosine sulfation
0.36	GO:0060468	prevention of polyspermy
0.36	GO:0042338	cuticle development involved in collagen and cuticulin-based cuticle molting cycle
0.36	GO:0007342	fusion of sperm to egg plasma membrane involved in single fertilization
0.36	GO:0061062	regulation of nematode larval development
0.36	GO:0032963	collagen metabolic process
0.35	GO:0006367	transcription initiation from RNA polymerase II promoter
0.35	GO:0040012	regulation of locomotion
0.35	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process
0.33	GO:0009306	protein secretion

0.84	GO:0008476	protein-tyrosine sulfotransferase activity
0.47	GO:0042803	protein homodimerization activity
0.33	GO:0005509	calcium ion binding
0.32	GO:0003676	nucleic acid binding
0.32	GO:0016787	hydrolase activity

0.46	GO:0012505	endomembrane system
0.42	GO:0043231	intracellular membrane-bounded organelle
0.41	GO:0044444	cytoplasmic part
0.38	GO:0031984	organelle subcompartment
0.38	GO:0098588	bounding membrane of organelle
0.35	GO:0070062	extracellular exosome
0.35	GO:0000428	DNA-directed RNA polymerase complex
0.34	GO:0005667	transcription factor complex
0.34	GO:0031974	membrane-enclosed lumen
0.30	GO:0016021	integral component of membrane

0.84

EC:2.8.2.20

GO:0008476

tr|T1G320|T1G320_HELRO
Uncharacterized protein
Search

TPGS2

0.67	Tubulin polyglutamylase complex subunit 2

0.62

GO:0018095

protein polyglutamylation

0.73	GO:0005874	microtubule
0.52	GO:0005829	cytosol

tr|T1G321|T1G321_HELRO
Uncharacterized protein
Search

TRMT13

0.91	Coiled-coil domain containing 76

0.66	GO:0008033	tRNA processing
0.63	GO:0032259	methylation
0.41	GO:0009451	RNA modification
0.36	GO:0044260	cellular macromolecule metabolic process
0.32	GO:0006520	cellular amino acid metabolic process

0.63	GO:0008168	methyltransferase activity
0.41	GO:0140101	catalytic activity, acting on a tRNA
0.33	GO:0004046	aminoacylase activity
0.33	GO:0046872	metal ion binding

0.31	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.63

GO:0008168

tr|T1G322|T1G322_HELRO
Uncharacterized protein
Search

SIGMAR1

0.96	sigma non-opioid intracellular receptor 1

0.54	GO:0070207	protein homotrimerization
0.52	GO:0043523	regulation of neuron apoptotic process
0.44	GO:0006869	lipid transport
0.37	GO:0009611	response to wounding

0.44

GO:0004872

receptor activity

0.54	GO:0005783	endoplasmic reticulum
0.53	GO:0005635	nuclear envelope
0.52	GO:0014069	postsynaptic density
0.45	GO:0031968	organelle outer membrane
0.43	GO:0031410	cytoplasmic vesicle
0.43	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.42	GO:0031984	organelle subcompartment
0.40	GO:0019866	organelle inner membrane
0.38	GO:0030426	growth cone
0.37	GO:0005811	lipid droplet

tr|T1G323|T1G323_HELRO
Uncharacterized protein
Search

0.83	Ligand-binding domain of nuclear hormone receptor

0.80	GO:0030522	intracellular receptor signaling pathway
0.79	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0060838	lymphatic endothelial cell fate commitment
0.48	GO:0001568	blood vessel development
0.47	GO:0009956	radial pattern formation
0.47	GO:0060707	trophoblast giant cell differentiation

0.82	GO:0004879	nuclear receptor activity
0.80	GO:0003707	steroid hormone receptor activity
0.63	GO:0043565	sequence-specific DNA binding
0.61	GO:0008270	zinc ion binding
0.47	GO:0001972	retinoic acid binding
0.44	GO:0042803	protein homodimerization activity
0.43	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.39	GO:0001012	RNA polymerase II regulatory region DNA binding
0.38	GO:0003690	double-stranded DNA binding
0.37	GO:0046982	protein heterodimerization activity

0.61	GO:0005634	nucleus
0.43	GO:0005829	cytosol
0.43	GO:0070013	intracellular organelle lumen
0.39	GO:0044446	intracellular organelle part

tr|T1G324|T1G324_HELRO
Uncharacterized protein
Search

tr|T1G325|T1G325_HELRO
Uncharacterized protein
Search

tr|T1G326|T1G326_HELRO
Uncharacterized protein
Search

0.57	E3 ubiquitin-protein ligase rififylin (Fragment)

0.59	GO:2001271	negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis
0.57	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.57	GO:1901797	negative regulation of signal transduction by p53 class mediator
0.56	GO:0070936	protein K48-linked ubiquitination
0.56	GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway
0.54	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.52	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.41	GO:2000374	regulation of oxygen metabolic process
0.40	GO:0035872	nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway
0.40	GO:0070417	cellular response to cold

0.55	GO:0002039	p53 binding
0.54	GO:0016874	ligase activity
0.53	GO:0002020	protease binding
0.53	GO:0031625	ubiquitin protein ligase binding
0.51	GO:0061630	ubiquitin protein ligase activity
0.51	GO:0019901	protein kinase binding
0.39	GO:0046872	metal ion binding
0.38	GO:1901981	phosphatidylinositol phosphate binding
0.36	GO:0008094	DNA-dependent ATPase activity
0.34	GO:0005524	ATP binding

0.58	GO:0002947	tumor necrosis factor receptor superfamily complex
0.51	GO:0010008	endosome membrane
0.42	GO:0005886	plasma membrane
0.39	GO:0016604	nuclear body
0.38	GO:0055037	recycling endosome
0.36	GO:0005764	lysosome
0.36	GO:0005829	cytosol
0.35	GO:0000139	Golgi membrane

0.54

GO:0016874

tr|T1G327|T1G327_HELRO
Uncharacterized protein
Search

RPL22

0.58	Chromodomain helicase DNA binding protein 5

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.46	GO:0030217	T cell differentiation
0.43	GO:0046631	alpha-beta T cell activation
0.36	GO:0060216	definitive hemopoiesis
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.33	GO:0019083	viral transcription

0.64	GO:0003735	structural constituent of ribosome
0.43	GO:0008201	heparin binding
0.40	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.61	GO:0005840	ribosome
0.43	GO:0044445	cytosolic part
0.38	GO:0044446	intracellular organelle part
0.38	GO:0005634	nucleus
0.36	GO:0031012	extracellular matrix
0.35	GO:0005925	focal adhesion
0.35	GO:0070062	extracellular exosome
0.34	GO:0005791	rough endoplasmic reticulum
0.34	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0098562	cytoplasmic side of membrane

tr|T1G328|T1G328_HELRO
Uncharacterized protein
Search

0.78	GO:0051321	meiotic cell cycle
0.44	GO:0035023	regulation of Rho protein signal transduction
0.41	GO:0065009	regulation of molecular function
0.40	GO:0006468	protein phosphorylation
0.34	GO:0032259	methylation
0.33	GO:0007165	signal transduction
0.33	GO:0043043	peptide biosynthetic process
0.33	GO:0010467	gene expression
0.33	GO:0009059	macromolecule biosynthetic process

0.44	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.40	GO:0004672	protein kinase activity
0.37	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0008168	methyltransferase activity
0.34	GO:0003735	structural constituent of ribosome

0.33	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.35

GO:0008168

tr|T1G329|T1G329_HELRO
Sphingomyelin phosphodiesterase
Search

SMPD1

0.52	Sphingomyelin phosphodiesterase

0.83	GO:0006685	sphingomyelin catabolic process
0.50	GO:0023021	termination of signal transduction
0.49	GO:0046513	ceramide biosynthetic process
0.48	GO:0035307	positive regulation of protein dephosphorylation
0.47	GO:0043407	negative regulation of MAP kinase activity
0.36	GO:0042220	response to cocaine
0.35	GO:0043065	positive regulation of apoptotic process
0.35	GO:0005975	carbohydrate metabolic process
0.34	GO:0007186	G-protein coupled receptor signaling pathway
0.34	GO:0006687	glycosphingolipid metabolic process

0.82	GO:0004767	sphingomyelin phosphodiesterase activity
0.60	GO:0016798	hydrolase activity, acting on glycosyl bonds
0.52	GO:0046872	metal ion binding
0.34	GO:0004930	G-protein coupled receptor activity
0.33	GO:0001653	peptide receptor activity
0.32	GO:0005515	protein binding

0.47	GO:0005764	lysosome
0.45	GO:0005768	endosome
0.44	GO:0005615	extracellular space
0.38	GO:0005886	plasma membrane
0.37	GO:0042599	lamellar body
0.35	GO:1903561	extracellular vesicle
0.34	GO:0044437	vacuolar part
0.33	GO:0045121	membrane raft
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0043233	organelle lumen

0.82	EC:3.1.4.12	GO:0004767
0.82	KEGG:R02541	GO:0004767

tr|T1G330|T1G330_HELRO
Uncharacterized protein
Search

0.45	Serine/threonine-protein kinase ICK

0.63

GO:0006468

protein phosphorylation

0.64	GO:0004672	protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

tr|T1G331|T1G331_HELRO
POU domain protein
Search

0.66	POU domain protein (Fragment)

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.42	GO:0010604	positive regulation of macromolecule metabolic process
0.42	GO:0001706	endoderm formation
0.42	GO:0060795	cell fate commitment involved in formation of primary germ layer
0.42	GO:0009786	regulation of asymmetric cell division
0.41	GO:0007398	ectoderm development
0.41	GO:0019827	stem cell population maintenance

0.63	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.45	GO:0035326	enhancer binding
0.45	GO:0019955	cytokine binding
0.42	GO:0003690	double-stranded DNA binding
0.41	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding
0.40	GO:0031625	ubiquitin protein ligase binding
0.40	GO:0031490	chromatin DNA binding
0.39	GO:0003714	transcription corepressor activity
0.39	GO:0046982	protein heterodimerization activity

0.61	GO:0005634	nucleus
0.42	GO:0000785	chromatin
0.41	GO:0070013	intracellular organelle lumen
0.39	GO:0017053	transcriptional repressor complex
0.39	GO:0005667	transcription factor complex
0.36	GO:0005829	cytosol
0.35	GO:0005739	mitochondrion
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1G332|T1G332_HELRO
Palmitoyltransferase
Search

ZDHHC16

0.48	Palmitoyltransferase

0.47	GO:0018345	protein palmitoylation
0.46	GO:0001654	eye development
0.45	GO:0007507	heart development
0.42	GO:0021899	fibroblast growth factor receptor signaling pathway involved in forebrain neuron fate commitment
0.42	GO:0021537	telencephalon development
0.41	GO:0006974	cellular response to DNA damage stimulus
0.36	GO:0006915	apoptotic process
0.32	GO:0055114	oxidation-reduction process

0.80	GO:0019706	protein-cysteine S-palmitoyltransferase activity
0.34	GO:0005515	protein binding
0.32	GO:0016491	oxidoreductase activity
0.31	GO:0016787	hydrolase activity

0.37	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.80

GO:0019706

tr|T1G333|T1G333_HELRO
Uncharacterized protein
Search

0.64	RNA-binding protein Musashi

0.42	GO:0007417	central nervous system development
0.36	GO:0050877	nervous system process
0.34	GO:0030154	cell differentiation
0.34	GO:0060429	epithelium development
0.33	GO:0009725	response to hormone

0.59	GO:0003723	RNA binding
0.44	GO:0042802	identical protein binding

0.47	GO:0005844	polysome
0.40	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1G334|T1G334_HELRO
Uncharacterized protein
Search

HUNK

0.67	Carbon catabolite derepressing protein kinase

0.63	GO:0006468	protein phosphorylation
0.39	GO:0030010	establishment of cell polarity
0.38	GO:0035556	intracellular signal transduction
0.38	GO:0000226	microtubule cytoskeleton organization
0.34	GO:0006887	exocytosis
0.34	GO:1902408	mitotic cytokinesis, site selection
0.33	GO:0061389	regulation of direction of cell growth
0.33	GO:0071963	establishment or maintenance of cell polarity regulating cell shape
0.33	GO:0030950	establishment or maintenance of actin cytoskeleton polarity
0.33	GO:0007009	plasma membrane organization

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005509	calcium ion binding
0.33	GO:0004197	cysteine-type endopeptidase activity
0.32	GO:0003735	structural constituent of ribosome
0.32	GO:0005515	protein binding
0.32	GO:0051287	NAD binding
0.32	GO:0003677	DNA binding

0.41	GO:0070985	TFIIK complex
0.35	GO:0005737	cytoplasm
0.34	GO:1990873	intrinsic component of plasma membrane of cell tip
0.34	GO:0035842	old cell tip after activation of bipolar cell growth
0.34	GO:0032178	medial membrane band
0.33	GO:0035841	new growing cell tip
0.33	GO:0035839	non-growing cell tip
0.32	GO:0030998	linear element
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016021	integral component of membrane

0.33

EC:3.4.22

GO:0004197

tr|T1G335|T1G335_HELRO
Uncharacterized protein
Search

0.79	Tctex1 domain-containing protein 2

0.69	GO:0001731	formation of translation preinitiation complex
0.68	GO:0006446	regulation of translational initiation

0.63

GO:0003743

translation initiation factor activity

0.68	GO:0016282	eukaryotic 43S preinitiation complex
0.68	GO:0033290	eukaryotic 48S preinitiation complex
0.68	GO:0005852	eukaryotic translation initiation factor 3 complex
0.30	GO:0016020	membrane

tr|T1G336|T1G336_HELRO
Uncharacterized protein
Search

tr|T1G337|T1G337_HELRO
Uncharacterized protein
Search

0.52	NADH:ubiquinone oxidoreductase domain containing protein

0.52

GO:0055114

oxidation-reduction process

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.60

GO:0005739

mitochondrion

0.69

GO:0008137

tr|T1G338|T1G338_HELRO
Uncharacterized protein
Search

0.55	T-box transcription factor TBX2

0.57	GO:0006351	transcription, DNA-templated
0.57	GO:0006355	regulation of transcription, DNA-templated
0.42	GO:0046884	follicle-stimulating hormone secretion
0.42	GO:0032275	luteinizing hormone secretion
0.41	GO:0030540	female genitalia development
0.41	GO:0009888	tissue development
0.41	GO:0045662	negative regulation of myoblast differentiation
0.41	GO:0042733	embryonic digit morphogenesis
0.41	GO:0035115	embryonic forelimb morphogenesis
0.41	GO:0030539	male genitalia development

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.39	GO:0001067	regulatory region nucleic acid binding
0.37	GO:0001102	RNA polymerase II activating transcription factor binding
0.34	GO:0051087	chaperone binding
0.34	GO:0031419	cobalamin binding
0.33	GO:0019899	enzyme binding

0.61	GO:0005634	nucleus
0.33	GO:0005667	transcription factor complex
0.32	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

tr|T1G339|T1G339_HELRO
Uncharacterized protein
Search

0.65	Transient receptor potential cation channel subfamily V member 6

0.60	GO:0034220	ion transmembrane transport
0.45	GO:0048060	negative gravitaxis
0.45	GO:0009612	response to mechanical stimulus
0.44	GO:0050884	neuromuscular process controlling posture
0.44	GO:0001964	startle response
0.44	GO:0007610	behavior
0.43	GO:0006816	calcium ion transport
0.42	GO:0009270	response to humidity
0.42	GO:0007600	sensory perception
0.39	GO:0022401	negative adaptation of signaling pathway

0.70	GO:0005216	ion channel activity
0.43	GO:0015085	calcium ion transmembrane transporter activity
0.32	GO:0005515	protein binding
0.32	GO:0046872	metal ion binding
0.32	GO:0004672	protein kinase activity
0.31	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.39	GO:0005887	integral component of plasma membrane
0.38	GO:0097730	non-motile cilium
0.38	GO:0043025	neuronal cell body
0.38	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0034703	cation channel complex

tr|T1G340|T1G340_HELRO
Uncharacterized protein
Search

DAPP1

0.97	Dual adapter for phosphotyrosine and 3-phosphotyrosine and

0.41	GO:0038083	peptidyl-tyrosine autophosphorylation
0.40	GO:0007165	signal transduction
0.40	GO:0045087	innate immune response
0.39	GO:0016477	cell migration
0.39	GO:0042127	regulation of cell proliferation
0.38	GO:0000413	protein peptidyl-prolyl isomerization
0.38	GO:0030154	cell differentiation
0.38	GO:0006470	protein dephosphorylation
0.36	GO:0043547	positive regulation of GTPase activity
0.35	GO:0072659	protein localization to plasma membrane

0.84	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding
0.83	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.63	GO:0030165	PDZ domain binding
0.40	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.38	GO:0005102	receptor binding
0.38	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.36	GO:0005096	GTPase activator activity
0.36	GO:0042169	SH2 domain binding
0.35	GO:0005070	SH3/SH2 adaptor activity
0.35	GO:0019903	protein phosphatase binding

0.54	GO:0005886	plasma membrane
0.41	GO:0005737	cytoplasm
0.39	GO:0098562	cytoplasmic side of membrane
0.39	GO:0019898	extrinsic component of membrane
0.35	GO:0043235	receptor complex
0.35	GO:0005911	cell-cell junction
0.33	GO:0005634	nucleus

0.40

GO:0004715

tr|T1G341|T1G341_HELRO
Uncharacterized protein
Search

tr|T1G342|T1G342_HELRO
Uncharacterized protein
Search

0.67	Complement component 1, q subcomponent-like protein

0.52	GO:0051259	protein oligomerization
0.49	GO:2000055	positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification
0.46	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.45	GO:0009953	dorsal/ventral pattern formation
0.39	GO:0048731	system development
0.38	GO:0032269	negative regulation of cellular protein metabolic process
0.38	GO:0030154	cell differentiation
0.38	GO:0009888	tissue development
0.37	GO:0060999	positive regulation of dendritic spine development
0.37	GO:0099175	regulation of postsynapse organization

0.52	GO:0042802	identical protein binding
0.40	GO:0005201	extracellular matrix structural constituent
0.37	GO:0004867	serine-type endopeptidase inhibitor activity
0.34	GO:0003723	RNA binding
0.34	GO:0030246	carbohydrate binding
0.33	GO:0046872	metal ion binding

0.70	GO:0005581	collagen trimer
0.55	GO:0005576	extracellular region
0.33	GO:0005886	plasma membrane
0.33	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

tr|T1G343|T1G343_HELRO
Uncharacterized protein
Search

tr|T1G344|T1G344_HELRO
Uncharacterized protein
Search

GBF1

0.89	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

0.80	GO:0032012	regulation of ARF protein signal transduction
0.65	GO:0065009	regulation of molecular function
0.59	GO:1903420	protein localization to endoplasmic reticulum tubular network
0.58	GO:0048205	COPI coating of Golgi vesicle
0.58	GO:0090166	Golgi disassembly
0.57	GO:0070973	protein localization to endoplasmic reticulum exit site
0.57	GO:0097111	endoplasmic reticulum-Golgi intermediate compartment organization
0.56	GO:0061162	establishment of monopolar cell polarity
0.55	GO:2000008	regulation of protein localization to cell surface
0.55	GO:0030593	neutrophil chemotaxis

0.80	GO:0005086	ARF guanyl-nucleotide exchange factor activity
0.55	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.54	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding
0.35	GO:0003700	DNA binding transcription factor activity
0.35	GO:0043565	sequence-specific DNA binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.54	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.53	GO:0005801	cis-Golgi network
0.53	GO:0005802	trans-Golgi network
0.52	GO:0031252	cell leading edge
0.49	GO:0000139	Golgi membrane
0.47	GO:0005829	cytosol
0.39	GO:0005788	endoplasmic reticulum lumen
0.38	GO:0005795	Golgi stack
0.38	GO:0005777	peroxisome
0.36	GO:0005811	lipid droplet

tr|T1G345|T1G345_HELRO
Uncharacterized protein
Search

0.65

GO:0016757

transferase activity, transferring glycosyl groups

0.30

GO:0044425

membrane part

0.65

GO:0016757

tr|T1G346|T1G346_HELRO
Uncharacterized protein
Search

0.68	GO:0045454	cell redox homeostasis
0.43	GO:0098869	cellular oxidant detoxification
0.43	GO:0031397	negative regulation of protein ubiquitination
0.42	GO:0030178	negative regulation of Wnt signaling pathway
0.41	GO:0072358	cardiovascular system development
0.36	GO:0030154	cell differentiation
0.36	GO:0016055	Wnt signaling pathway
0.35	GO:0055114	oxidation-reduction process
0.35	GO:0080092	regulation of pollen tube growth
0.35	GO:0010183	pollen tube guidance

0.47	GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor
0.46	GO:0015036	disulfide oxidoreductase activity
0.43	GO:0016209	antioxidant activity
0.33	GO:0005515	protein binding
0.33	GO:0003743	translation initiation factor activity
0.32	GO:0008270	zinc ion binding
0.32	GO:0016746	transferase activity, transferring acyl groups
0.32	GO:0003735	structural constituent of ribosome
0.32	GO:0016829	lyase activity
0.32	GO:0016853	isomerase activity

0.37	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.32	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

0.47

EC:1.8.1

GO:0016668

tr|T1G347|T1G347_HELRO
Uncharacterized protein
Search

SLC25A12

0.61	Calcium-binding mitochondrial carrier protein Aralar1

0.58	GO:0043490	malate-aspartate shuttle
0.57	GO:0089712	L-aspartate transmembrane transport
0.53	GO:0089711	L-glutamate transmembrane transport
0.52	GO:0051592	response to calcium ion
0.36	GO:0006754	ATP biosynthetic process
0.33	GO:0019319	hexose biosynthetic process
0.33	GO:0006006	glucose metabolic process
0.32	GO:0006518	peptide metabolic process
0.32	GO:0043604	amide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process

0.70	GO:0005509	calcium ion binding
0.57	GO:0015183	L-aspartate transmembrane transporter activity
0.53	GO:0005313	L-glutamate transmembrane transporter activity
0.33	GO:0003735	structural constituent of ribosome

0.50	GO:0043209	myelin sheath
0.44	GO:0031966	mitochondrial membrane
0.44	GO:0019866	organelle inner membrane
0.32	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

tr|T1G348|T1G348_HELRO
Uncharacterized protein
Search

0.70	Myotubularin-related protein 13

0.68	GO:0043087	regulation of GTPase activity
0.56	GO:0035556	intracellular signal transduction
0.42	GO:0051262	protein tetramerization

0.71	GO:0019208	phosphatase regulator activity
0.49	GO:0046872	metal ion binding
0.43	GO:0017112	Rab guanyl-nucleotide exchange factor activity
0.42	GO:0019902	phosphatase binding
0.41	GO:0035091	phosphatidylinositol binding
0.40	GO:0042803	protein homodimerization activity

0.42	GO:0005622	intracellular
0.40	GO:0098805	whole membrane
0.39	GO:0098588	bounding membrane of organelle

tr|T1G349|T1G349_HELRO
Uncharacterized protein
Search

0.75	Sodium-coupled monocarboxylate transporter

0.55	GO:0055085	transmembrane transport
0.34	GO:0006915	apoptotic process
0.34	GO:0006814	sodium ion transport
0.34	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway
0.33	GO:0015718	monocarboxylic acid transport
0.33	GO:0042891	antibiotic transport
0.32	GO:0005975	carbohydrate metabolic process

0.57

GO:0022857

transmembrane transporter activity

0.35	GO:0016324	apical plasma membrane
0.34	GO:0070062	extracellular exosome
0.32	GO:0005887	integral component of plasma membrane
0.32	GO:0005739	mitochondrion

tr|T1G350|T1G350_HELRO
Uncharacterized protein
Search

0.74	Gamma-aminobutyric acid receptor subunit rho-2

0.61	GO:0007165	signal transduction
0.60	GO:0034220	ion transmembrane transport
0.42	GO:0006821	chloride transport
0.40	GO:0042391	regulation of membrane potential
0.40	GO:0031987	locomotion involved in locomotory behavior
0.40	GO:0043051	regulation of pharyngeal pumping
0.39	GO:0007601	visual perception
0.39	GO:0007268	chemical synaptic transmission
0.35	GO:0042462	eye photoreceptor cell development
0.35	GO:0042493	response to drug

0.75	GO:0005230	extracellular ligand-gated ion channel activity
0.70	GO:0004888	transmembrane signaling receptor activity
0.42	GO:0005254	chloride channel activity
0.41	GO:0099095	ligand-gated anion channel activity
0.35	GO:0019904	protein domain specific binding
0.35	GO:0016594	glycine binding
0.33	GO:0070001	aspartic-type peptidase activity
0.33	GO:0004175	endopeptidase activity
0.33	GO:0003700	DNA binding transcription factor activity
0.32	GO:0003676	nucleic acid binding

0.54	GO:0005886	plasma membrane
0.41	GO:1902711	GABA-A receptor complex
0.40	GO:0098794	postsynapse
0.36	GO:0034707	chloride channel complex
0.35	GO:0030054	cell junction
0.34	GO:0030424	axon

tr|T1G351|T1G351_HELRO
Uncharacterized protein
Search

0.60	Cardioacceleratory peptide receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.47	GO:0032870	cellular response to hormone stimulus
0.46	GO:1901652	response to peptide
0.41	GO:1901699	cellular response to nitrogen compound
0.39	GO:1901701	cellular response to oxygen-containing compound
0.39	GO:0007268	chemical synaptic transmission
0.37	GO:0007210	serotonin receptor signaling pathway
0.36	GO:0065008	regulation of biological quality
0.36	GO:0032501	multicellular organismal process
0.35	GO:0042060	wound healing

0.72	GO:0004930	G-protein coupled receptor activity
0.52	GO:0016500	protein-hormone receptor activity
0.50	GO:0001653	peptide receptor activity
0.45	GO:0042277	peptide binding
0.39	GO:0030594	neurotransmitter receptor activity
0.37	GO:0099589	serotonin receptor activity
0.35	GO:0051378	serotonin binding
0.35	GO:0008081	phosphoric diester hydrolase activity
0.34	GO:0004984	olfactory receptor activity
0.33	GO:0005515	protein binding

0.42	GO:0005887	integral component of plasma membrane
0.38	GO:0005654	nucleoplasm
0.38	GO:0043005	neuron projection

0.35

EC:3.1.4

GO:0008081

tr|T1G352|T1G352_HELRO
Carboxypeptidase
Search

CPVL

0.47	Serine carboxypeptidase CPVL

0.61	GO:0006508	proteolysis
0.43	GO:0044257	cellular protein catabolic process
0.36	GO:0033227	dsRNA transport

0.75	GO:0004185	serine-type carboxypeptidase activity
0.33	GO:0004252	serine-type endopeptidase activity

0.36	GO:0070062	extracellular exosome
0.33	GO:0005773	vacuole
0.30	GO:0031224	intrinsic component of membrane

0.75

EC:3.4.16

GO:0004185

tr|T1G353|T1G353_HELRO
Uncharacterized protein
Search

TBC1D19

0.96	TBC1 domain family member 19 isoform B

0.55	GO:1902017	regulation of cilium assembly
0.51	GO:0043547	positive regulation of GTPase activity

0.51	GO:0005096	GTPase activator activity
0.41	GO:0005515	protein binding

0.30

GO:0044425

membrane part

tr|T1G354|T1G354_HELRO
Uncharacterized protein
Search

0.73	LIM domain only protein 4

0.46	GO:0035483	gastric emptying
0.45	GO:0036011	imaginal disc-derived leg segmentation
0.44	GO:0042220	response to cocaine
0.44	GO:0022416	chaeta development
0.44	GO:0045475	locomotor rhythm
0.44	GO:0007476	imaginal disc-derived wing morphogenesis
0.43	GO:0008593	regulation of Notch signaling pathway
0.41	GO:1903508	positive regulation of nucleic acid-templated transcription
0.41	GO:0010628	positive regulation of gene expression
0.40	GO:0022414	reproductive process

0.54	GO:0046872	metal ion binding
0.36	GO:0005515	protein binding
0.33	GO:0016740	transferase activity

0.35	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.33

GO:0016740

tr|T1G355|T1G355_HELRO
Uncharacterized protein
Search

0.36

GO:0006313

transposition, DNA-mediated

0.51	GO:0003676	nucleic acid binding
0.36	GO:0004803	transposase activity
0.36	GO:0046872	metal ion binding

0.30

GO:0031224

intrinsic component of membrane

tr|T1G356|T1G356_HELRO
Ubiquitinyl hydrolase 1
Search

USP49

0.44	Ubiquitinyl hydrolase 1

0.76	GO:0016579	protein deubiquitination
0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.50	GO:0000398	mRNA splicing, via spliceosome
0.50	GO:0016570	histone modification
0.40	GO:1904667	negative regulation of ubiquitin protein ligase activity

0.76	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.63	GO:0008270	zinc ion binding
0.52	GO:0042393	histone binding
0.50	GO:0004197	cysteine-type endopeptidase activity

0.36

GO:0005634

nucleus

0.76