Queries 18001 to 19000

GO:0016874

tr|T1FUJ8|T1FUJ8_HELRO
Uncharacterized protein
Search

0.59	GO:0035556	intracellular signal transduction
0.42	GO:0010761	fibroblast migration
0.41	GO:0007044	cell-substrate junction assembly
0.37	GO:0016310	phosphorylation
0.35	GO:0001100	negative regulation of exit from mitosis
0.34	GO:0009272	fungal-type cell wall biogenesis
0.34	GO:0043547	positive regulation of GTPase activity
0.34	GO:0043213	bacteriocin transport
0.34	GO:0032259	methylation
0.34	GO:0007062	sister chromatid cohesion

0.49	GO:0046872	metal ion binding
0.37	GO:0016301	kinase activity
0.35	GO:0003779	actin binding
0.35	GO:0008455	alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity
0.34	GO:0005096	GTPase activator activity
0.34	GO:0008168	methyltransferase activity
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding

0.44	GO:0005622	intracellular
0.41	GO:0005912	adherens junction
0.40	GO:0030055	cell-substrate junction
0.35	GO:0009986	cell surface
0.35	GO:1902773	GTPase activator complex
0.34	GO:0043228	non-membrane-bounded organelle
0.33	GO:0044422	organelle part
0.33	GO:0012505	endomembrane system
0.32	GO:0043227	membrane-bounded organelle
0.30	GO:0016020	membrane

0.35

EC:2.4.1.143

GO:0008455

tr|T1FUJ9|T1FUJ9_HELRO
Uncharacterized protein
Search

ACAD8

0.50	Isobutyryl-CoA dehydrogenaseserine-threonine

0.56	GO:0006629	lipid metabolic process
0.53	GO:0055114	oxidation-reduction process
0.37	GO:0006574	valine catabolic process
0.34	GO:0000387	spliceosomal snRNP assembly
0.33	GO:0035335	peptidyl-tyrosine dephosphorylation
0.32	GO:0006351	transcription, DNA-templated
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.74	GO:0003995	acyl-CoA dehydrogenase activity
0.66	GO:0050660	flavin adenine dinucleotide binding
0.33	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.33	GO:0004725	protein tyrosine phosphatase activity
0.32	GO:0046872	metal ion binding

0.34	GO:0032797	SMN complex
0.34	GO:0005739	mitochondrion
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.74

EC:1.3.99.3

GO:0003995

tr|T1FUK0|T1FUK0_HELRO
Uncharacterized protein
Search

tr|T1FUK1|T1FUK1_HELRO
Uncharacterized protein
Search

0.70

GO:0006397

mRNA processing

0.54

GO:0046872

metal ion binding

0.30

GO:0031224

intrinsic component of membrane

tr|T1FUK2|T1FUK2_HELRO
Uncharacterized protein
Search

tr|T1FUK3|T1FUK3_HELRO
Uncharacterized protein
Search

tr|T1FUK4|T1FUK4_HELRO
Uncharacterized protein
Search

0.54	GO:0048149	behavioral response to ethanol
0.53	GO:0007616	long-term memory
0.49	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.48	GO:0016567	protein ubiquitination
0.38	GO:1900095	regulation of dosage compensation by inactivation of X chromosome
0.38	GO:0060816	random inactivation of X chromosome
0.37	GO:0001578	microtubule bundle formation
0.36	GO:0000910	cytokinesis

0.50	GO:0016874	ligase activity
0.49	GO:0061630	ubiquitin protein ligase activity
0.42	GO:0008270	zinc ion binding
0.36	GO:0008017	microtubule binding

0.36	GO:0005634	nucleus
0.35	GO:0005856	cytoskeleton
0.30	GO:0016020	membrane

0.50

GO:0016874

tr|T1FUK5|T1FUK5_HELRO
Uncharacterized protein
Search

tr|T1FUK6|T1FUK6_HELRO
Uncharacterized protein
Search

0.69	GO:0006401	RNA catabolic process
0.45	GO:0016071	mRNA metabolic process
0.45	GO:0030968	endoplasmic reticulum unfolded protein response
0.45	GO:0010629	negative regulation of gene expression
0.35	GO:0035864	response to potassium ion
0.34	GO:0040029	regulation of gene expression, epigenetic
0.34	GO:0051607	defense response to virus
0.33	GO:0006417	regulation of translation
0.33	GO:0006813	potassium ion transport
0.33	GO:0016310	phosphorylation

0.73	GO:0003724	RNA helicase activity
0.57	GO:0003723	RNA binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0008186	RNA-dependent ATPase activity
0.41	GO:0070035	purine NTP-dependent helicase activity
0.34	GO:0019205	nucleobase-containing compound kinase activity
0.33	GO:0005515	protein binding
0.32	GO:0003677	DNA binding

0.55	GO:0055087	Ski complex
0.34	GO:0005773	vacuole
0.33	GO:0005829	cytosol
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.73

GO:0003724

tr|T1FUK7|T1FUK7_HELRO
Uncharacterized protein
Search

tr|T1FUK8|T1FUK8_HELRO
Uncharacterized protein
Search

0.52	GO:0031161	phosphatidylinositol catabolic process
0.51	GO:2001135	regulation of endocytic recycling
0.51	GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein
0.51	GO:0001921	positive regulation of receptor recycling
0.50	GO:0003299	muscle hypertrophy in response to stress
0.50	GO:0014887	cardiac muscle adaptation
0.50	GO:0003300	cardiac muscle hypertrophy
0.50	GO:0048681	negative regulation of axon regeneration
0.48	GO:0008344	adult locomotory behavior
0.47	GO:0046856	phosphatidylinositol dephosphorylation

0.68	GO:0042578	phosphoric ester hydrolase activity
0.46	GO:0042803	protein homodimerization activity
0.34	GO:0016706	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
0.34	GO:0031418	L-ascorbic acid binding
0.33	GO:0005506	iron ion binding
0.32	GO:0016301	kinase activity

0.49	GO:0045334	clathrin-coated endocytic vesicle
0.48	GO:0055037	recycling endosome
0.48	GO:0005905	clathrin-coated pit
0.48	GO:0005769	early endosome
0.47	GO:0043025	neuronal cell body
0.47	GO:0030425	dendrite
0.47	GO:0030424	axon
0.34	GO:0010008	endosome membrane
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0042578

tr|T1FUK9|T1FUK9_HELRO
Uncharacterized protein
Search

0.38	GO:0035556	intracellular signal transduction
0.37	GO:0006468	protein phosphorylation
0.37	GO:0035023	regulation of Rho protein signal transduction
0.35	GO:0065009	regulation of molecular function

0.41	GO:0005543	phospholipid binding
0.39	GO:0005509	calcium ion binding
0.39	GO:0016162	cellulose 1,4-beta-cellobiosidase activity
0.37	GO:0004672	protein kinase activity
0.37	GO:0005515	protein binding
0.36	GO:0098772	molecular function regulator
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.34	GO:0005622	intracellular
0.30	GO:0016020	membrane

0.39

EC:3.2.1.91

GO:0016162

tr|T1FUL0|T1FUL0_HELRO
Uncharacterized protein
Search

0.56	GO:0007219	Notch signaling pathway
0.52	GO:0007155	cell adhesion
0.51	GO:0032501	multicellular organismal process
0.50	GO:0030154	cell differentiation
0.49	GO:0048856	anatomical structure development
0.48	GO:0050793	regulation of developmental process
0.41	GO:0042060	wound healing
0.39	GO:0007599	hemostasis
0.39	GO:0045967	negative regulation of growth rate
0.38	GO:0046579	positive regulation of Ras protein signal transduction

0.70	GO:0005509	calcium ion binding
0.42	GO:0005178	integrin binding
0.40	GO:0060089	molecular transducer activity
0.38	GO:0004252	serine-type endopeptidase activity
0.37	GO:0005112	Notch binding
0.37	GO:0008270	zinc ion binding
0.36	GO:0042802	identical protein binding
0.34	GO:0051059	NF-kappaB binding
0.34	GO:0008429	phosphatidylethanolamine binding
0.34	GO:0001786	phosphatidylserine binding

0.46	GO:0005604	basement membrane
0.43	GO:0005615	extracellular space
0.42	GO:0005886	plasma membrane
0.39	GO:0043235	receptor complex
0.37	GO:0009986	cell surface
0.36	GO:0005654	nucleoplasm
0.34	GO:1903561	extracellular vesicle
0.33	GO:0005929	cilium
0.33	GO:0019898	extrinsic component of membrane
0.33	GO:0098552	side of membrane

0.38

GO:0004252

tr|T1FUL1|T1FUL1_HELRO
Uncharacterized protein
Search

tr|T1FUL2|T1FUL2_HELRO
Uncharacterized protein
Search

tr|T1FUL3|T1FUL3_HELRO
Uncharacterized protein
Search

0.53	GO:0055114	oxidation-reduction process
0.36	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.35	GO:0034219	carbohydrate transmembrane transport
0.35	GO:0009401	phosphoenolpyruvate-dependent sugar phosphotransferase system

0.54	GO:0016491	oxidoreductase activity
0.35	GO:0008982	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
0.35	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses
0.35	GO:0004842	ubiquitin-protein transferase activity
0.34	GO:0016887	ATPase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.36	GO:0031463	Cul3-RING ubiquitin ligase complex
0.30	GO:0016020	membrane

0.54	EC:1	GO:0016491
0.35	KEGG:R03876	GO:0004842

tr|T1FUL4|T1FUL4_HELRO
Uncharacterized protein
Search

tr|T1FUL5|T1FUL5_HELRO
Uncharacterized protein
Search

tr|T1FUL6|T1FUL6_HELRO
Uncharacterized protein
Search

tr|T1FUL7|T1FUL7_HELRO
Uncharacterized protein
Search

0.72	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic
0.71	GO:0006402	mRNA catabolic process
0.56	GO:0110008	ncRNA deadenylation
0.55	GO:0090669	telomerase RNA stabilization
0.54	GO:1904872	regulation of telomerase RNA localization to Cajal body
0.53	GO:0051973	positive regulation of telomerase activity
0.53	GO:0032212	positive regulation of telomere maintenance via telomerase
0.34	GO:0022414	reproductive process
0.34	GO:0043488	regulation of mRNA stability
0.34	GO:0032501	multicellular organismal process

0.82	GO:0004535	poly(A)-specific ribonuclease activity
0.57	GO:0003723	RNA binding
0.52	GO:0046872	metal ion binding
0.49	GO:0019901	protein kinase binding

0.59	GO:0005634	nucleus
0.47	GO:0005737	cytoplasm
0.34	GO:0043233	organelle lumen
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.82

EC:3.1.13.4

GO:0004535

tr|T1FUL8|T1FUL8_HELRO
Uncharacterized protein
Search

0.45	GO:2001141	regulation of RNA biosynthetic process
0.45	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.45	GO:0010468	regulation of gene expression
0.40	GO:0016310	phosphorylation
0.39	GO:0019538	protein metabolic process
0.39	GO:0043412	macromolecule modification
0.39	GO:0043326	chemotaxis to folate
0.39	GO:0060176	regulation of aggregation involved in sorocarp development
0.38	GO:0043327	chemotaxis to cAMP
0.38	GO:0031272	regulation of pseudopodium assembly

0.47	GO:0046982	protein heterodimerization activity
0.43	GO:0003677	DNA binding
0.41	GO:0016301	kinase activity
0.41	GO:0140096	catalytic activity, acting on a protein
0.40	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.40	GO:0003712	transcription cofactor activity
0.38	GO:0030554	adenyl nucleotide binding
0.37	GO:0097367	carbohydrate derivative binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding

0.51	GO:0005634	nucleus
0.41	GO:0070013	intracellular organelle lumen
0.39	GO:0044446	intracellular organelle part
0.37	GO:1902494	catalytic complex
0.36	GO:0005694	chromosome
0.36	GO:0020011	apicoplast
0.36	GO:0099512	supramolecular fiber
0.36	GO:0015630	microtubule cytoskeleton
0.35	GO:0043234	protein complex
0.35	GO:0097458	neuron part

0.40

GO:0016773

tr|T1FUL9|T1FUL9_HELRO
Uncharacterized protein
Search

0.42	GO:0065007	biological regulation
0.40	GO:0006606	protein import into nucleus
0.39	GO:0006907	pinocytosis
0.38	GO:0044260	cellular macromolecule metabolic process
0.38	GO:0051716	cellular response to stimulus
0.38	GO:0097659	nucleic acid-templated transcription
0.38	GO:0036211	protein modification process
0.38	GO:0023052	signaling
0.38	GO:0007154	cell communication
0.38	GO:0009272	fungal-type cell wall biogenesis

0.41	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.40	GO:0043565	sequence-specific DNA binding
0.39	GO:0005515	protein binding
0.39	GO:0030234	enzyme regulator activity
0.38	GO:0140096	catalytic activity, acting on a protein
0.38	GO:0008270	zinc ion binding
0.37	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.37	GO:0016301	kinase activity
0.37	GO:0001012	RNA polymerase II regulatory region DNA binding
0.37	GO:0004491	methylmalonate-semialdehyde dehydrogenase (acylating) activity

0.44	GO:0005634	nucleus
0.37	GO:0030015	CCR4-NOT core complex
0.37	GO:0000932	P-body
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.37

GO:0016773

tr|T1FUM0|T1FUM0_HELRO
Uncharacterized protein
Search

DARS2

0.65	Aspartyl-tRNA synthetase

0.67	GO:0006418	tRNA aminoacylation for protein translation
0.53	GO:0000959	mitochondrial RNA metabolic process
0.52	GO:0032543	mitochondrial translation

0.68	GO:0016875	ligase activity, forming carbon-oxygen bonds
0.65	GO:0140101	catalytic activity, acting on a tRNA
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0042803	protein homodimerization activity
0.49	GO:0003676	nucleic acid binding
0.34	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
0.34	GO:0005509	calcium ion binding

0.49	GO:0005737	cytoplasm
0.44	GO:0005634	nucleus
0.36	GO:0031974	membrane-enclosed lumen
0.34	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.68	EC:6.1	GO:0016875
0.34	KEGG:R05982 KEGG:R06722	GO:0004571

tr|T1FUM1|T1FUM1_HELRO
Uncharacterized protein
Search

0.44	GO:0006468	protein phosphorylation
0.42	GO:0046854	phosphatidylinositol phosphorylation
0.41	GO:0032501	multicellular organismal process
0.40	GO:0030154	cell differentiation
0.40	GO:0048856	anatomical structure development
0.39	GO:0006508	proteolysis
0.39	GO:0035988	chondrocyte proliferation
0.39	GO:0120036	plasma membrane bounded cell projection organization
0.39	GO:0002175	protein localization to paranode region of axon
0.39	GO:0050808	synapse organization

0.45	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.45	GO:0016301	kinase activity
0.44	GO:0140096	catalytic activity, acting on a protein
0.42	GO:0030554	adenyl nucleotide binding
0.42	GO:0005509	calcium ion binding
0.42	GO:0097367	carbohydrate derivative binding
0.42	GO:0008144	drug binding
0.42	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0017171	serine hydrolase activity
0.39	GO:0005515	protein binding

0.39	GO:0033010	paranodal junction
0.39	GO:0043194	axon initial segment
0.38	GO:0033270	paranode region of axon
0.37	GO:0043209	myelin sheath
0.37	GO:0097454	Schwann cell microvillus
0.35	GO:0030425	dendrite
0.35	GO:0043231	intracellular membrane-bounded organelle
0.35	GO:0009986	cell surface
0.35	GO:0031012	extracellular matrix
0.35	GO:0005886	plasma membrane

0.45	EC:2.7.1	GO:0016773
0.36	KEGG:R04463	GO:0004642

tr|T1FUM2|T1FUM2_HELRO
Uncharacterized protein
Search

tr|T1FUM3|T1FUM3_HELRO
Uncharacterized protein
Search

0.54	GO:0006955	immune response
0.53	GO:0006898	receptor-mediated endocytosis
0.42	GO:0007165	signal transduction
0.41	GO:0050829	defense response to Gram-negative bacterium
0.41	GO:0006909	phagocytosis
0.39	GO:0043087	regulation of GTPase activity
0.39	GO:0005975	carbohydrate metabolic process
0.39	GO:0009405	pathogenesis
0.38	GO:0007399	nervous system development
0.38	GO:0120039	plasma membrane bounded cell projection morphogenesis

0.58	GO:0005044	scavenger receptor activity
0.56	GO:0001871	pattern binding
0.53	GO:0030246	carbohydrate binding
0.39	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.39	GO:0046982	protein heterodimerization activity
0.36	GO:0008233	peptidase activity
0.36	GO:0004930	G-protein coupled receptor activity
0.35	GO:0005509	calcium ion binding
0.35	GO:0003682	chromatin binding
0.34	GO:0008484	sulfuric ester hydrolase activity

0.40	GO:0005576	extracellular region
0.35	GO:0016324	apical plasma membrane
0.34	GO:0005887	integral component of plasma membrane
0.33	GO:0005634	nucleus

0.39

GO:0004553

tr|T1FUM4|T1FUM4_HELRO
Uncharacterized protein
Search

tr|T1FUM5|T1FUM5_HELRO
Uncharacterized protein
Search

tr|T1FUM6|T1FUM6_HELRO
Uncharacterized protein
Search

0.61	GO:0035023	regulation of Rho protein signal transduction
0.54	GO:0065009	regulation of molecular function
0.46	GO:0018095	protein polyglutamylation
0.45	GO:0035556	intracellular signal transduction
0.38	GO:0055085	transmembrane transport
0.37	GO:2001141	regulation of RNA biosynthetic process
0.37	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.37	GO:0010468	regulation of gene expression
0.37	GO:0016180	snRNA processing
0.36	GO:0008643	carbohydrate transport

0.62	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.41	GO:0030554	adenyl nucleotide binding
0.41	GO:0043168	anion binding
0.40	GO:0097367	carbohydrate derivative binding
0.40	GO:0008144	drug binding
0.40	GO:0043492	ATPase activity, coupled to movement of substances
0.39	GO:0015405	P-P-bond-hydrolysis-driven transmembrane transporter activity
0.37	GO:0003700	DNA binding transcription factor activity
0.37	GO:0008289	lipid binding
0.37	GO:0140096	catalytic activity, acting on a protein

0.39	GO:0005634	nucleus
0.37	GO:0000428	DNA-directed RNA polymerase complex
0.36	GO:0070013	intracellular organelle lumen
0.35	GO:0043234	protein complex
0.35	GO:0044446	intracellular organelle part
0.34	GO:0031248	protein acetyltransferase complex
0.33	GO:0000151	ubiquitin ligase complex
0.33	GO:1905368	peptidase complex
0.33	GO:0005694	chromosome
0.32	GO:0005739	mitochondrion

0.35	EC:2.7.1	GO:0016773
0.34	KEGG:R01801	GO:0008444

tr|T1FUM7|T1FUM7_HELRO
alpha-1,2-Mannosidase
Search

0.21	alpha-1,2-Mannosidase

0.48	GO:0006491	N-glycan processing
0.41	GO:0097466	ubiquitin-dependent glycoprotein ERAD pathway
0.38	GO:0006517	protein deglycosylation
0.38	GO:0030968	endoplasmic reticulum unfolded protein response
0.35	GO:0009101	glycoprotein biosynthetic process
0.35	GO:0006029	proteoglycan metabolic process
0.34	GO:0006013	mannose metabolic process
0.34	GO:0035010	encapsulation of foreign target
0.34	GO:0043413	macromolecule glycosylation
0.32	GO:0098655	cation transmembrane transport

0.82	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
0.70	GO:0005509	calcium ion binding
0.33	GO:0031625	ubiquitin protein ligase binding
0.32	GO:0008324	cation transmembrane transporter activity

0.44	GO:0005783	endoplasmic reticulum
0.43	GO:0000139	Golgi membrane
0.34	GO:0070062	extracellular exosome
0.33	GO:0031301	integral component of organelle membrane
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network

0.82	EC:3.2.1.113	GO:0004571
0.82	KEGG:R05982 KEGG:R06722	GO:0004571

tr|T1FUM8|T1FUM8_HELRO
Uncharacterized protein
Search

tr|T1FUM9|T1FUM9_HELRO
Uncharacterized protein
Search

tr|T1FUN0|T1FUN0_HELRO
Uncharacterized protein
Search

tr|T1FUN1|T1FUN1_HELRO
Uncharacterized protein
Search

tr|T1FUN2|T1FUN2_HELRO
Uncharacterized protein
Search

tr|T1FUN3|T1FUN3_HELRO
Uncharacterized protein
Search

tr|T1FUN4|T1FUN4_HELRO
Uncharacterized protein
Search

tr|T1FUN5|T1FUN5_HELRO
Uncharacterized protein
Search

tr|T1FUN6|T1FUN6_HELRO
Uncharacterized protein
Search

0.62	Glycine receptor subunit beta

0.61	GO:0007165	signal transduction
0.60	GO:0034220	ion transmembrane transport
0.35	GO:0006821	chloride transport
0.35	GO:0060012	synaptic transmission, glycinergic
0.34	GO:0043200	response to amino acid
0.34	GO:0060078	regulation of postsynaptic membrane potential
0.33	GO:0019538	protein metabolic process
0.32	GO:0006355	regulation of transcription, DNA-templated
0.32	GO:0043412	macromolecule modification
0.32	GO:0016310	phosphorylation

0.75	GO:0005230	extracellular ligand-gated ion channel activity
0.70	GO:0004888	transmembrane signaling receptor activity
0.35	GO:0016594	glycine binding
0.35	GO:0099095	ligand-gated anion channel activity
0.34	GO:0005254	chloride channel activity
0.33	GO:0070001	aspartic-type peptidase activity
0.33	GO:0044877	macromolecular complex binding
0.33	GO:0004674	protein serine/threonine kinase activity
0.33	GO:0140110	transcription regulator activity
0.33	GO:0004175	endopeptidase activity

0.54	GO:0005886	plasma membrane
0.35	GO:1902711	GABA-A receptor complex
0.34	GO:0098794	postsynapse
0.32	GO:0016592	mediator complex
0.30	GO:0016021	integral component of membrane

0.33

GO:0004674

tr|T1FUN7|T1FUN7_HELRO
Uncharacterized protein
Search

tr|T1FUN8|T1FUN8_HELRO
Uncharacterized protein
Search

tr|T1FUN9|T1FUN9_HELRO
Uncharacterized protein
Search

tr|T1FUP0|T1FUP0_HELRO
Uncharacterized protein
Search

0.27	Aminopeptidase

0.80	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I
0.75	GO:0008217	regulation of blood pressure
0.60	GO:0006508	proteolysis
0.48	GO:0045766	positive regulation of angiogenesis
0.47	GO:0043171	peptide catabolic process
0.45	GO:0007267	cell-cell signaling
0.41	GO:0007165	signal transduction
0.38	GO:0002250	adaptive immune response
0.37	GO:0030163	protein catabolic process
0.34	GO:0045444	fat cell differentiation

0.71	GO:0070006	metalloaminopeptidase activity
0.63	GO:0008270	zinc ion binding
0.54	GO:0005138	interleukin-6 receptor binding
0.47	GO:0042277	peptide binding
0.35	GO:0005151	interleukin-1, Type II receptor binding
0.35	GO:0004175	endopeptidase activity
0.34	GO:0005164	tumor necrosis factor receptor binding

0.65	GO:0005783	endoplasmic reticulum
0.65	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.61	GO:0031984	organelle subcompartment
0.45	GO:0005576	extracellular region
0.39	GO:0005886	plasma membrane
0.39	GO:0031982	vesicle
0.38	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0031090	organelle membrane
0.34	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.34	GO:0043233	organelle lumen

tr|T1FUP1|T1FUP1_HELRO
Uncharacterized protein
Search

tr|T1FUP2|T1FUP2_HELRO
Uncharacterized protein
Search

tr|T1FUP3|T1FUP3_HELRO
Uncharacterized protein
Search

0.45	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA
0.42	GO:0006359	regulation of transcription by RNA polymerase III
0.42	GO:0006383	transcription by RNA polymerase III
0.42	GO:0043085	positive regulation of catalytic activity
0.42	GO:0006429	leucyl-tRNA aminoacylation
0.41	GO:0016567	protein ubiquitination
0.40	GO:0048015	phosphatidylinositol-mediated signaling
0.40	GO:0106074	aminoacyl-tRNA metabolism involved in translational fidelity
0.39	GO:0046854	phosphatidylinositol phosphorylation
0.37	GO:0007017	microtubule-based process

0.43	GO:0001026	TFIIIB-type transcription factor activity
0.42	GO:0008047	enzyme activator activity
0.42	GO:0004842	ubiquitin-protein transferase activity
0.42	GO:0004823	leucine-tRNA ligase activity
0.40	GO:0002161	aminoacyl-tRNA editing activity
0.40	GO:0003676	nucleic acid binding
0.38	GO:0008270	zinc ion binding
0.38	GO:0030554	adenyl nucleotide binding
0.37	GO:0003700	DNA binding transcription factor activity
0.37	GO:0097367	carbohydrate derivative binding

0.43	GO:0000126	transcription factor TFIIIB complex
0.36	GO:0005737	cytoplasm
0.35	GO:0035770	ribonucleoprotein granule
0.35	GO:0031965	nuclear membrane
0.35	GO:0044430	cytoskeletal part
0.34	GO:0030015	CCR4-NOT core complex
0.34	GO:0015630	microtubule cytoskeleton
0.34	GO:0009986	cell surface
0.34	GO:0005886	plasma membrane
0.34	GO:0016592	mediator complex

0.42	EC:6.1.1.4	GO:0004823
0.42	KEGG:R03876	GO:0004842

tr|T1FUP4|T1FUP4_HELRO
Uncharacterized protein
Search

tr|T1FUP5|T1FUP5_HELRO
Uncharacterized protein
Search

tr|T1FUP6|T1FUP6_HELRO
Uncharacterized protein
Search

tr|T1FUP7|T1FUP7_HELRO
Uncharacterized protein
Search

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.51	GO:0001889	liver development
0.50	GO:0030968	endoplasmic reticulum unfolded protein response
0.48	GO:0006366	transcription by RNA polymerase II
0.48	GO:0048785	hatching gland development
0.48	GO:0060691	epithelial cell maturation involved in salivary gland development
0.48	GO:0035188	hatching
0.47	GO:1900100	positive regulation of plasma cell differentiation

0.61	GO:0003700	DNA binding transcription factor activity
0.47	GO:0044212	transcription regulatory region DNA binding
0.47	GO:1990837	sequence-specific double-stranded DNA binding
0.44	GO:0001085	RNA polymerase II transcription factor binding
0.42	GO:0046982	protein heterodimerization activity
0.38	GO:0031490	chromatin DNA binding
0.37	GO:0002020	protease binding
0.37	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding
0.36	GO:0031625	ubiquitin protein ligase binding
0.36	GO:0019901	protein kinase binding

0.42	GO:0005634	nucleus
0.41	GO:0005783	endoplasmic reticulum
0.36	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0031984	organelle subcompartment
0.35	GO:0005829	cytosol
0.34	GO:0098793	presynapse
0.33	GO:0070013	intracellular organelle lumen
0.30	GO:0016021	integral component of membrane

tr|T1FUP8|T1FUP8_HELRO
Uncharacterized protein
Search

tr|T1FUP9|T1FUP9_HELRO
Uncharacterized protein
Search

VPS4A

0.60	Vacuolar protein sorting-associated protein 4

0.46	GO:0045470	R8 cell-mediated photoreceptor organization
0.45	GO:0045463	R8 cell development
0.44	GO:0044130	negative regulation of growth of symbiont in host
0.44	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway
0.44	GO:0016322	neuron remodeling
0.43	GO:0097352	autophagosome maturation
0.43	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
0.43	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity
0.43	GO:0045746	negative regulation of Notch signaling pathway
0.41	GO:0007010	cytoskeleton organization

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0016887	ATPase activity
0.34	GO:0046983	protein dimerization activity
0.34	GO:0008022	protein C-terminus binding
0.34	GO:0005198	structural molecule activity
0.34	GO:0140096	catalytic activity, acting on a protein
0.34	GO:0042802	identical protein binding

0.36	GO:0005634	nucleus
0.36	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0010008	endosome membrane
0.35	GO:0090543	Flemming body
0.34	GO:0036452	ESCRT complex
0.34	GO:0000922	spindle pole
0.34	GO:0005813	centrosome
0.33	GO:0005829	cytosol
0.33	GO:1904949	ATPase complex
0.33	GO:0098796	membrane protein complex

0.37

GO:0016887

tr|T1FUQ0|T1FUQ0_HELRO
Uncharacterized protein
Search

tr|T1FUQ1|T1FUQ1_HELRO
Uncharacterized protein
Search

0.37	Phosphorylase b kinase regulatory subunit

0.73	GO:0005977	glycogen metabolic process
0.51	GO:0016310	phosphorylation
0.37	GO:0036211	protein modification process
0.36	GO:0044267	cellular protein metabolic process
0.34	GO:0006108	malate metabolic process
0.33	GO:0006099	tricarboxylic acid cycle
0.33	GO:0006508	proteolysis

0.77	GO:0005516	calmodulin binding
0.53	GO:0016301	kinase activity
0.37	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.37	GO:0140096	catalytic activity, acting on a protein
0.34	GO:0030060	L-malate dehydrogenase activity
0.33	GO:0017171	serine hydrolase activity

0.53	GO:0005886	plasma membrane
0.43	GO:0005964	phosphorylase kinase complex
0.30	GO:0016021	integral component of membrane

0.37

GO:0016773

tr|T1FUQ2|T1FUQ2_HELRO
Uncharacterized protein
Search

tr|T1FUQ3|T1FUQ3_HELRO
Uncharacterized protein
Search

tr|T1FUQ4|T1FUQ4_HELRO
Uncharacterized protein
Search

0.37	von Willebrand factor A domain-containing protein 2-like

tr|T1FUQ5|T1FUQ5_HELRO
Uncharacterized protein
Search

tr|T1FUQ6|T1FUQ6_HELRO
Uncharacterized protein
Search

0.63	GO:0098789	pre-mRNA cleavage required for polyadenylation
0.59	GO:0006378	mRNA polyadenylation
0.43	GO:0032509	endosome transport via multivesicular body sorting pathway
0.40	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.40	GO:0018108	peptidyl-tyrosine phosphorylation
0.40	GO:0072277	metanephric glomerular capillary formation
0.39	GO:0000398	mRNA splicing, via spliceosome
0.39	GO:0001553	luteinization
0.39	GO:0033327	Leydig cell differentiation
0.39	GO:0023019	signal transduction involved in regulation of gene expression

0.49	GO:0003723	RNA binding
0.44	GO:0032266	phosphatidylinositol-3-phosphate binding
0.43	GO:0043130	ubiquitin binding
0.41	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.39	GO:0048407	platelet-derived growth factor binding
0.37	GO:0030674	protein binding, bridging
0.37	GO:0004842	ubiquitin-protein transferase activity
0.37	GO:0004930	G-protein coupled receptor activity
0.37	GO:0032403	protein complex binding
0.36	GO:0046872	metal ion binding

0.73	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex
0.44	GO:0000814	ESCRT II complex
0.38	GO:0005902	microvillus
0.38	GO:0000439	core TFIIH complex
0.38	GO:0009897	external side of plasma membrane
0.38	GO:0031902	late endosome membrane
0.38	GO:0071013	catalytic step 2 spliceosome
0.30	GO:0016021	integral component of membrane

0.41	EC:2.7.10.1	GO:0004714
0.37	KEGG:R03876	GO:0004842

tr|T1FUQ7|T1FUQ7_HELRO
Uncharacterized protein
Search

0.70	GO:0061007	hepaticobiliary system process
0.44	GO:0016310	phosphorylation

0.45

GO:0016301

kinase activity

0.57	GO:0019013	viral nucleocapsid
0.50	GO:1990904	ribonucleoprotein complex
0.40	GO:0044424	intracellular part

tr|T1FUQ8|T1FUQ8_HELRO
Uncharacterized protein
Search

tr|T1FUQ9|T1FUQ9_HELRO
Uncharacterized protein
Search

tr|T1FUR0|T1FUR0_HELRO
Uncharacterized protein
Search

0.52

GO:0008033

tRNA processing

0.45	GO:0030554	adenyl nucleotide binding
0.45	GO:0097367	carbohydrate derivative binding
0.45	GO:0008144	drug binding
0.45	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0046872	metal ion binding
0.43	GO:0016740	transferase activity

0.30

GO:0031224

intrinsic component of membrane

0.43

GO:0016740

tr|T1FUR1|T1FUR1_HELRO
Uncharacterized protein
Search

0.65	GO:0006414	translational elongation
0.42	GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter
0.37	GO:0051571	positive regulation of histone H3-K4 methylation
0.37	GO:0006352	DNA-templated transcription, initiation
0.36	GO:0045944	positive regulation of transcription by RNA polymerase II
0.34	GO:0009736	cytokinin-activated signaling pathway
0.34	GO:0010104	regulation of ethylene-activated signaling pathway
0.34	GO:0006325	chromatin organization
0.34	GO:0009867	jasmonic acid mediated signaling pathway
0.33	GO:0051016	barbed-end actin filament capping

0.66	GO:0003746	translation elongation factor activity
0.38	GO:0046982	protein heterodimerization activity
0.36	GO:0003682	chromatin binding
0.33	GO:0001102	RNA polymerase II activating transcription factor binding
0.33	GO:0140110	transcription regulator activity
0.33	GO:0017025	TBP-class protein binding
0.33	GO:0004402	histone acetyltransferase activity
0.33	GO:0003743	translation initiation factor activity
0.32	GO:0140096	catalytic activity, acting on a protein
0.32	GO:0017171	serine hydrolase activity

0.42	GO:0032021	NELF complex
0.39	GO:0046695	SLIK (SAGA-like) complex
0.39	GO:0000124	SAGA complex
0.39	GO:0005669	transcription factor TFIID complex
0.38	GO:0016604	nuclear body
0.36	GO:0005829	cytosol
0.33	GO:0017053	transcriptional repressor complex
0.33	GO:0030479	actin cortical patch
0.33	GO:0005694	chromosome
0.30	GO:0016020	membrane

0.33

GO:0004402

tr|T1FUR2|T1FUR2_HELRO
Uncharacterized protein
Search

tr|T1FUR3|T1FUR3_HELRO
Uncharacterized protein
Search

0.42	Serine proteinase

0.61	GO:0006508	proteolysis
0.51	GO:0042730	fibrinolysis
0.50	GO:0007596	blood coagulation
0.49	GO:0048771	tissue remodeling
0.45	GO:0006898	receptor-mediated endocytosis
0.45	GO:0052213	interaction with symbiont via secreted substance involved in symbiotic interaction
0.44	GO:0052212	modification of morphology or physiology of other organism via secreted substance involved in symbiotic interaction
0.44	GO:0051919	positive regulation of fibrinolysis
0.43	GO:0060707	trophoblast giant cell differentiation
0.43	GO:0051918	negative regulation of fibrinolysis

0.69	GO:0004252	serine-type endopeptidase activity
0.48	GO:0005044	scavenger receptor activity
0.44	GO:1904854	proteasome core complex binding
0.44	GO:1990405	protein antigen binding
0.43	GO:0034185	apolipoprotein binding
0.43	GO:0019900	kinase binding
0.40	GO:0019904	protein domain specific binding
0.40	GO:0051087	chaperone binding
0.40	GO:0005102	receptor binding
0.38	GO:0005509	calcium ion binding

0.48	GO:0005576	extracellular region
0.43	GO:0031232	extrinsic component of external side of plasma membrane
0.38	GO:0044218	other organism cell membrane
0.34	GO:0031093	platelet alpha granule lumen
0.33	GO:1990777	lipoprotein particle
0.32	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.69

GO:0004252

tr|T1FUR4|T1FUR4_HELRO
Uncharacterized protein
Search

0.11	Sorting nexin-13

0.50	GO:0043547	positive regulation of GTPase activity
0.39	GO:0010667	negative regulation of cardiac muscle cell apoptotic process
0.38	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway
0.35	GO:0005975	carbohydrate metabolic process
0.33	GO:0009057	macromolecule catabolic process
0.33	GO:0030154	cell differentiation
0.33	GO:0048731	system development
0.33	GO:0006030	chitin metabolic process
0.33	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.32	GO:0015074	DNA integration

0.74	GO:0035091	phosphatidylinositol binding
0.35	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.34	GO:0030246	carbohydrate binding
0.33	GO:0050661	NADP binding
0.33	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.33	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.33	GO:0051287	NAD binding
0.33	GO:0008061	chitin binding
0.32	GO:0001871	pattern binding
0.32	GO:0003676	nucleic acid binding

0.34	GO:0005576	extracellular region
0.32	GO:0031982	vesicle
0.30	GO:0016020	membrane

0.35

GO:0004553

tr|T1FUR5|T1FUR5_HELRO
Uncharacterized protein
Search

tr|T1FUR6|T1FUR6_HELRO
Uncharacterized protein
Search

0.50	GO:0048015	phosphatidylinositol-mediated signaling
0.49	GO:0046488	phosphatidylinositol metabolic process
0.49	GO:0030258	lipid modification
0.45	GO:0043137	DNA replication, removal of RNA primer
0.42	GO:0033554	cellular response to stress
0.42	GO:0016310	phosphorylation
0.41	GO:2001141	regulation of RNA biosynthetic process
0.41	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.41	GO:0010468	regulation of gene expression
0.40	GO:0099120	socially cooperative development

0.45	GO:0048256	flap endonuclease activity
0.43	GO:0008409	5'-3' exonuclease activity
0.43	GO:0016301	kinase activity
0.42	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters
0.42	GO:0003677	DNA binding
0.42	GO:0140110	transcription regulator activity
0.40	GO:0052832	inositol monophosphate 3-phosphatase activity
0.40	GO:0052833	inositol monophosphate 4-phosphatase activity
0.40	GO:0000287	magnesium ion binding
0.40	GO:0008934	inositol monophosphate 1-phosphatase activity

0.48	GO:0005634	nucleus
0.42	GO:0070013	intracellular organelle lumen
0.41	GO:0044446	intracellular organelle part
0.40	GO:0031461	cullin-RING ubiquitin ligase complex
0.39	GO:0043232	intracellular non-membrane-bounded organelle
0.39	GO:0005739	mitochondrion
0.37	GO:0000331	contractile vacuole
0.36	GO:0005829	cytosol
0.36	GO:0012505	endomembrane system
0.35	GO:0005618	cell wall

0.42

EC:3.1.21

GO:0016888

tr|T1FUR7|T1FUR7_HELRO
Uncharacterized protein
Search

tr|T1FUR8|T1FUR8_HELRO
Uncharacterized protein
Search

tr|T1FUR9|T1FUR9_HELRO
Uncharacterized protein
Search

tr|T1FUS0|T1FUS0_HELRO
Uncharacterized protein
Search

tr|T1FUS1|T1FUS1_HELRO
Uncharacterized protein
Search

tr|T1FUS2|T1FUS2_HELRO
Uncharacterized protein
Search

tr|T1FUS3|T1FUS3_HELRO
Uncharacterized protein
Search

tr|T1FUS4|T1FUS4_HELRO
Uncharacterized protein
Search

tr|T1FUS5|T1FUS5_HELRO
Uncharacterized protein
Search

0.54	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.40	GO:0006307	DNA dealkylation involved in DNA repair
0.40	GO:0048488	synaptic vesicle endocytosis
0.39	GO:0032418	lysosome localization
0.37	GO:0006351	transcription, DNA-templated
0.37	GO:0006486	protein glycosylation
0.36	GO:0006508	proteolysis
0.36	GO:0005975	carbohydrate metabolic process

0.40	GO:0005199	structural constituent of cell wall
0.38	GO:0008378	galactosyltransferase activity
0.37	GO:0030246	carbohydrate binding
0.37	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.36	GO:0008233	peptidase activity

0.85	GO:0099053	activating signal cointegrator 1 complex
0.58	GO:0005634	nucleus
0.38	GO:0045202	synapse
0.37	GO:0031974	membrane-enclosed lumen
0.36	GO:0005794	Golgi apparatus
0.35	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.38

GO:0008378

tr|T1FUS6|T1FUS6_HELRO
Uncharacterized protein
Search

tr|T1FUS7|T1FUS7_HELRO
Uncharacterized protein
Search

0.71	GO:0007166	cell surface receptor signaling pathway
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.50	GO:0019933	cAMP-mediated signaling
0.49	GO:0060347	heart trabecula formation
0.48	GO:0022011	myelination in peripheral nervous system
0.44	GO:0007005	mitochondrion organization
0.35	GO:0009952	anterior/posterior pattern specification
0.35	GO:0009792	embryo development ending in birth or egg hatching
0.35	GO:0097264	self proteolysis
0.35	GO:0019953	sexual reproduction

0.72	GO:0004930	G-protein coupled receptor activity
0.48	GO:0043236	laminin binding
0.48	GO:0030246	carbohydrate binding
0.35	GO:0042803	protein homodimerization activity
0.35	GO:0005509	calcium ion binding
0.34	GO:0005518	collagen binding
0.34	GO:0004175	endopeptidase activity

0.40	GO:0005886	plasma membrane
0.36	GO:0005622	intracellular
0.34	GO:0009986	cell surface
0.30	GO:0016021	integral component of membrane

tr|T1FUS8|T1FUS8_HELRO
Uncharacterized protein
Search

0.62

GO:0035335

peptidyl-tyrosine dephosphorylation

0.62

GO:0004725

protein tyrosine phosphatase activity

0.35	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.62

GO:0004725

tr|T1FUS9|T1FUS9_HELRO
Uncharacterized protein
Search

tr|T1FUT0|T1FUT0_HELRO
Uncharacterized protein
Search

tr|T1FUT1|T1FUT1_HELRO
Uncharacterized protein
Search

tr|T1FUT2|T1FUT2_HELRO
Uncharacterized protein
Search

0.68	GO:0019318	hexose metabolic process
0.34	GO:0046365	monosaccharide catabolic process
0.33	GO:0046835	carbohydrate phosphorylation
0.33	GO:0000160	phosphorelay signal transduction system

0.76	GO:0004034	aldose 1-epimerase activity
0.70	GO:0030246	carbohydrate binding
0.34	GO:0004335	galactokinase activity
0.33	GO:0000287	magnesium ion binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.32	GO:0005622	intracellular
0.30	GO:0031224	intrinsic component of membrane

0.76	EC:5.1.3.3	GO:0004034
0.34	KEGG:R01092	GO:0004335

tr|T1FUT3|T1FUT3_HELRO
Uncharacterized protein
Search

0.49

GO:0006508

proteolysis

0.60	GO:0005201	extracellular matrix structural constituent
0.54	GO:0070001	aspartic-type peptidase activity
0.51	GO:0004175	endopeptidase activity
0.50	GO:0004386	helicase activity
0.44	GO:0030554	adenyl nucleotide binding
0.43	GO:0097367	carbohydrate derivative binding
0.43	GO:0008144	drug binding
0.43	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0003676	nucleic acid binding

0.57

GO:0005578

proteinaceous extracellular matrix

tr|T1FUT4|T1FUT4_HELRO
Uncharacterized protein
Search

0.79	GO:0045663	positive regulation of myoblast differentiation
0.75	GO:0007224	smoothened signaling pathway
0.73	GO:0045664	regulation of neuron differentiation
0.71	GO:0048598	embryonic morphogenesis
0.64	GO:0014816	skeletal muscle satellite cell differentiation
0.63	GO:0043497	regulation of protein heterodimerization activity
0.62	GO:0048643	positive regulation of skeletal muscle tissue development
0.61	GO:2000179	positive regulation of neural precursor cell proliferation
0.61	GO:0007520	myoblast fusion
0.60	GO:0002088	lens development in camera-type eye

0.46	GO:0005112	Notch binding
0.40	GO:0005509	calcium ion binding
0.37	GO:0004872	receptor activity

0.62	GO:0005887	integral component of plasma membrane
0.37	GO:0009986	cell surface

tr|T1FUT5|T1FUT5_HELRO
Uncharacterized protein
Search

tr|T1FUT6|T1FUT6_HELRO
Uncharacterized protein
Search

tr|T1FUT7|T1FUT7_HELRO
Uncharacterized protein
Search

0.63	GO:0006629	lipid metabolic process
0.47	GO:0071926	endocannabinoid signaling pathway
0.46	GO:0036269	swimming behavior
0.46	GO:0007634	optokinetic behavior
0.43	GO:0007409	axonogenesis
0.37	GO:0007405	neuroblast proliferation
0.36	GO:0006690	icosanoid metabolic process
0.36	GO:0042136	neurotransmitter biosynthetic process
0.35	GO:1901575	organic substance catabolic process
0.35	GO:0055114	oxidation-reduction process

0.51	GO:0016787	hydrolase activity
0.37	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.33	GO:0004930	G-protein coupled receptor activity
0.32	GO:0046872	metal ion binding

0.34	GO:0005634	nucleus
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.51

GO:0016787

tr|T1FUT8|T1FUT8_HELRO
Uncharacterized protein
Search

tr|T1FUT9|T1FUT9_HELRO
Uncharacterized protein
Search

LOC106169064

0.69	Exocyst complex component 2

0.84	GO:0006893	Golgi to plasma membrane transport
0.45	GO:0048214	regulation of Golgi vesicle fusion to target membrane
0.44	GO:0071896	protein localization to adherens junction
0.44	GO:0035147	branch fusion, open tracheal system
0.44	GO:0045056	transcytosis
0.44	GO:0031340	positive regulation of vesicle fusion
0.44	GO:0001927	exocyst assembly
0.43	GO:0072697	protein localization to cell cortex
0.43	GO:0007349	cellularization
0.43	GO:0007298	border follicle cell migration

0.42	GO:0017137	Rab GTPase binding
0.37	GO:0017160	Ral GTPase binding
0.36	GO:0047485	protein N-terminus binding
0.34	GO:0019901	protein kinase binding
0.34	GO:0005509	calcium ion binding
0.32	GO:0003676	nucleic acid binding

0.79	GO:0000145	exocyst
0.44	GO:0005642	annulate lamellae
0.44	GO:0035003	subapical complex
0.44	GO:0016028	rhabdomere
0.42	GO:0055037	recycling endosome
0.41	GO:0030136	clathrin-coated vesicle
0.34	GO:0098793	presynapse
0.30	GO:0016021	integral component of membrane

tr|T1FUU0|T1FUU0_HELRO
Uncharacterized protein
Search

tr|T1FUU1|T1FUU1_HELRO
Uncharacterized protein
Search

tr|T1FUU2|T1FUU2_HELRO
Uncharacterized protein
Search

0.41	GO:0035989	tendon development
0.41	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound
0.41	GO:0001502	cartilage condensation
0.41	GO:0002063	chondrocyte development
0.40	GO:0090596	sensory organ morphogenesis
0.40	GO:0035987	endodermal cell differentiation
0.40	GO:0055010	ventricular cardiac muscle tissue morphogenesis
0.40	GO:0030199	collagen fibril organization
0.40	GO:0050953	sensory perception of light stimulus
0.40	GO:0006029	proteoglycan metabolic process

0.66	GO:0042302	structural constituent of cuticle
0.53	GO:0005201	extracellular matrix structural constituent
0.37	GO:0003676	nucleic acid binding
0.36	GO:0003700	DNA binding transcription factor activity
0.34	GO:0004713	protein tyrosine kinase activity
0.34	GO:0003777	microtubule motor activity
0.34	GO:0005096	GTPase activator activity
0.34	GO:0046983	protein dimerization activity
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0008168	methyltransferase activity

0.61	GO:0005581	collagen trimer
0.41	GO:0098643	banded collagen fibril
0.39	GO:0005634	nucleus
0.38	GO:0005615	extracellular space
0.37	GO:0005667	transcription factor complex
0.35	GO:0033596	TSC1-TSC2 complex
0.35	GO:0045202	synapse
0.34	GO:0000786	nucleosome
0.30	GO:0016020	membrane

0.34

EC:2.7.10

GO:0004713

tr|T1FUU3|T1FUU3_HELRO
Uncharacterized protein
Search

0.60	GO:0005975	carbohydrate metabolic process
0.42	GO:0007186	G-protein coupled receptor signaling pathway

0.42	GO:0004930	G-protein coupled receptor activity
0.38	GO:0030246	carbohydrate binding
0.35	GO:0016787	hydrolase activity

0.40	GO:0005618	cell wall
0.30	GO:0044425	membrane part

0.35

GO:0016787

tr|T1FUU4|T1FUU4_HELRO
Uncharacterized protein
Search

0.36	GO:0045162	clustering of voltage-gated sodium channels
0.36	GO:0001525	angiogenesis
0.35	GO:0006928	movement of cell or subcellular component
0.35	GO:0007155	cell adhesion
0.35	GO:0007409	axonogenesis
0.34	GO:0042221	response to chemical
0.34	GO:0098870	action potential propagation
0.34	GO:0042330	taxis
0.34	GO:0007017	microtubule-based process
0.34	GO:0019226	transmission of nerve impulse

0.36	GO:0030506	ankyrin binding
0.34	GO:0086080	protein binding involved in heterotypic cell-cell adhesion
0.34	GO:0004896	cytokine receptor activity
0.34	GO:0003777	microtubule motor activity
0.34	GO:0003714	transcription corepressor activity
0.34	GO:0042393	histone binding
0.33	GO:0050839	cell adhesion molecule binding
0.33	GO:0004722	protein serine/threonine phosphatase activity
0.33	GO:0019904	protein domain specific binding
0.33	GO:0004832	valine-tRNA ligase activity

0.36	GO:0030424	axon
0.35	GO:0030426	growth cone
0.34	GO:0005634	nucleus
0.34	GO:0043025	neuronal cell body
0.33	GO:0009986	cell surface
0.33	GO:0045202	synapse
0.33	GO:0031012	extracellular matrix
0.33	GO:0005886	plasma membrane
0.33	GO:0030286	dynein complex
0.30	GO:0016021	integral component of membrane

0.33	EC:6.1.1.9	GO:0004832
0.33	KEGG:R03665	GO:0004832

tr|T1FUU5|T1FUU5_HELRO
Uncharacterized protein
Search

0.52	GO:0007017	microtubule-based process
0.38	GO:0031156	regulation of sorocarp development
0.38	GO:0043412	macromolecule modification
0.37	GO:0050794	regulation of cellular process
0.37	GO:0000278	mitotic cell cycle
0.37	GO:0046907	intracellular transport
0.37	GO:0010467	gene expression
0.37	GO:0010556	regulation of macromolecule biosynthetic process
0.37	GO:0051171	regulation of nitrogen compound metabolic process
0.37	GO:0080090	regulation of primary metabolic process

0.38	GO:0046872	metal ion binding
0.38	GO:0003676	nucleic acid binding
0.37	GO:0005515	protein binding
0.37	GO:0004672	protein kinase activity
0.36	GO:0030554	adenyl nucleotide binding
0.36	GO:0097367	carbohydrate derivative binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0140110	transcription regulator activity
0.35	GO:0042623	ATPase activity, coupled

0.57	GO:0005869	dynactin complex
0.39	GO:0005634	nucleus
0.37	GO:0005815	microtubule organizing center
0.36	GO:0000922	spindle pole
0.36	GO:0012505	endomembrane system
0.36	GO:0070013	intracellular organelle lumen
0.35	GO:0044433	cytoplasmic vesicle part
0.35	GO:0005874	microtubule
0.35	GO:0042641	actomyosin
0.35	GO:0005829	cytosol

0.35	EC:5.4.99.12	GO:0009982
0.35	KEGG:R01801	GO:0008444

tr|T1FUU6|T1FUU6_HELRO
Uncharacterized protein
Search

0.43	GO:0005975	carbohydrate metabolic process
0.43	GO:0042545	cell wall modification
0.43	GO:0070098	chemokine-mediated signaling pathway
0.40	GO:0006935	chemotaxis
0.40	GO:0007186	G-protein coupled receptor signaling pathway

0.43	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.43	GO:0045330	aspartyl esterase activity
0.43	GO:0030599	pectinesterase activity
0.43	GO:0004950	chemokine receptor activity
0.42	GO:0008061	chitin binding
0.41	GO:0030246	carbohydrate binding

0.41	GO:0005618	cell wall
0.40	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.43

GO:0004553

tr|T1FUU7|T1FUU7_HELRO
Uncharacterized protein
Search

tr|T1FUU8|T1FUU8_HELRO
Uncharacterized protein
Search

0.46	GO:0006342	chromatin silencing
0.44	GO:0016570	histone modification
0.43	GO:0018393	internal peptidyl-lysine acetylation
0.42	GO:0002064	epithelial cell development
0.42	GO:0006413	translational initiation
0.41	GO:0007374	posterior midgut invagination
0.41	GO:0048383	mesectoderm development
0.41	GO:0048646	anatomical structure formation involved in morphogenesis
0.41	GO:0043519	regulation of myosin II filament organization
0.40	GO:0007362	terminal region determination

0.43	GO:0004402	histone acetyltransferase activity
0.43	GO:0050825	ice binding
0.42	GO:0003743	translation initiation factor activity
0.39	GO:0001664	G-protein coupled receptor binding
0.39	GO:0003714	transcription corepressor activity
0.38	GO:0003713	transcription coactivator activity
0.38	GO:0017171	serine hydrolase activity
0.38	GO:0031177	phosphopantetheine binding
0.38	GO:0008061	chitin binding
0.37	GO:0042802	identical protein binding

0.43	GO:0000781	chromosome, telomeric region
0.40	GO:0032221	Rpd3S complex
0.40	GO:0033698	Rpd3L complex
0.39	GO:0009277	fungal-type cell wall
0.36	GO:0005576	extracellular region
0.36	GO:0005829	cytosol
0.35	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.43

GO:0004402

tr|T1FUU9|T1FUU9_HELRO
Uncharacterized protein
Search

0.39	GO:0035335	peptidyl-tyrosine dephosphorylation
0.36	GO:0014066	regulation of phosphatidylinositol 3-kinase signaling
0.34	GO:0006886	intracellular protein transport
0.34	GO:0006429	leucyl-tRNA aminoacylation
0.33	GO:0106074	aminoacyl-tRNA metabolism involved in translational fidelity
0.33	GO:0006508	proteolysis
0.33	GO:0006355	regulation of transcription, DNA-templated
0.32	GO:0006629	lipid metabolic process
0.32	GO:0005975	carbohydrate metabolic process
0.32	GO:0055114	oxidation-reduction process

0.79	GO:0032947	protein complex scaffold activity
0.39	GO:0004725	protein tyrosine phosphatase activity
0.37	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding
0.35	GO:0032266	phosphatidylinositol-3-phosphate binding
0.34	GO:0102965	alcohol-forming fatty acyl-CoA reductase activity
0.34	GO:0080019	fatty-acyl-CoA reductase (alcohol-forming) activity
0.34	GO:0004823	leucine-tRNA ligase activity
0.33	GO:0002161	aminoacyl-tRNA editing activity
0.33	GO:0008233	peptidase activity
0.33	GO:0043565	sequence-specific DNA binding

0.37	GO:0005856	cytoskeleton
0.37	GO:0012505	endomembrane system
0.36	GO:0030027	lamellipodium
0.34	GO:0005634	nucleus
0.33	GO:0005886	plasma membrane
0.33	GO:0005737	cytoplasm
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016021	integral component of membrane

0.39	EC:3.1.3.48	GO:0004725
0.34	KEGG:R03657	GO:0004823

tr|T1FUV0|T1FUV0_HELRO
Uncharacterized protein
Search

0.83	GO:1902902	negative regulation of autophagosome assembly
0.61	GO:0007411	axon guidance
0.42	GO:0008088	axo-dendritic transport
0.41	GO:0017157	regulation of exocytosis
0.38	GO:0015031	protein transport
0.37	GO:0007165	signal transduction

0.42

GO:0019894

kinesin binding

0.61	GO:0030424	axon
0.42	GO:0005744	mitochondrial inner membrane presequence translocase complex
0.38	GO:0005856	cytoskeleton
0.30	GO:0031224	intrinsic component of membrane

tr|T1FUV1|T1FUV1_HELRO
Uncharacterized protein
Search

0.47	GO:0006888	ER to Golgi vesicle-mediated transport
0.45	GO:0006886	intracellular protein transport
0.44	GO:0060255	regulation of macromolecule metabolic process
0.44	GO:0071310	cellular response to organic substance
0.43	GO:0031326	regulation of cellular biosynthetic process
0.43	GO:0051171	regulation of nitrogen compound metabolic process
0.43	GO:0080090	regulation of primary metabolic process
0.43	GO:0009733	response to auxin
0.42	GO:0071495	cellular response to endogenous stimulus
0.42	GO:0006325	chromatin organization

0.42	GO:0005515	protein binding
0.42	GO:0050825	ice binding
0.41	GO:0016286	small conductance calcium-activated potassium channel activity
0.41	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.41	GO:0140110	transcription regulator activity
0.41	GO:0004540	ribonuclease activity
0.40	GO:0098772	molecular function regulator
0.40	GO:0045735	nutrient reservoir activity
0.39	GO:0003677	DNA binding
0.39	GO:0008270	zinc ion binding

0.48	GO:0030127	COPII vesicle coat
0.47	GO:0005634	nucleus
0.43	GO:1990234	transferase complex
0.43	GO:0070013	intracellular organelle lumen
0.40	GO:0030015	CCR4-NOT core complex
0.40	GO:0005765	lysosomal membrane
0.40	GO:0000932	P-body
0.39	GO:1905368	peptidase complex
0.30	GO:0016021	integral component of membrane

0.39

GO:0008233

tr|T1FUV2|T1FUV2_HELRO
Uncharacterized protein
Search

0.54	GO:0030041	actin filament polymerization
0.50	GO:0061371	determination of heart left/right asymmetry
0.48	GO:0044782	cilium organization
0.46	GO:0006508	proteolysis
0.42	GO:0007018	microtubule-based movement
0.41	GO:0006470	protein dephosphorylation

0.47	GO:0008233	peptidase activity
0.42	GO:0003777	microtubule motor activity
0.41	GO:0004721	phosphoprotein phosphatase activity
0.41	GO:0005509	calcium ion binding

0.47	GO:0005634	nucleus
0.41	GO:0015629	actin cytoskeleton
0.30	GO:0016020	membrane

0.47

GO:0008233

tr|T1FUV3|T1FUV3_HELRO
Uncharacterized protein
Search

tr|T1FUV4|T1FUV4_HELRO
Uncharacterized protein
Search

0.60	GO:0006508	proteolysis
0.48	GO:0051604	protein maturation
0.46	GO:0006898	receptor-mediated endocytosis
0.37	GO:0007596	blood coagulation
0.36	GO:2000331	regulation of terminal button organization
0.35	GO:0006030	chitin metabolic process
0.33	GO:0030001	metal ion transport
0.32	GO:0016310	phosphorylation

0.68	GO:0004252	serine-type endopeptidase activity
0.49	GO:0005044	scavenger receptor activity
0.41	GO:0005509	calcium ion binding
0.35	GO:0008061	chitin binding
0.33	GO:0016301	kinase activity

0.47	GO:0005576	extracellular region
0.34	GO:0016324	apical plasma membrane
0.33	GO:0043235	receptor complex
0.30	GO:0016021	integral component of membrane

0.68

GO:0004252

tr|T1FUV5|T1FUV5_HELRO
Uncharacterized protein
Search

0.61	GO:0006508	proteolysis
0.54	GO:0001867	complement activation, lectin pathway
0.43	GO:0007596	blood coagulation
0.39	GO:0065009	regulation of molecular function
0.36	GO:0006468	protein phosphorylation

0.69	GO:0004252	serine-type endopeptidase activity
0.49	GO:0001855	complement component C4b binding
0.48	GO:0005509	calcium ion binding
0.46	GO:0048306	calcium-dependent protein binding
0.44	GO:0017080	sodium channel regulator activity
0.37	GO:0030246	carbohydrate binding
0.36	GO:0004672	protein kinase activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.46	GO:0046658	anchored component of plasma membrane
0.45	GO:0019897	extrinsic component of plasma membrane
0.42	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.69

GO:0004252

tr|T1FUV6|T1FUV6_HELRO
Uncharacterized protein
Search

0.51	GO:0016032	viral process
0.37	GO:0048477	oogenesis
0.37	GO:0019538	protein metabolic process
0.36	GO:0051276	chromosome organization
0.36	GO:0002066	columnar/cuboidal epithelial cell development
0.36	GO:0006898	receptor-mediated endocytosis
0.36	GO:0009405	pathogenesis
0.36	GO:0090304	nucleic acid metabolic process
0.35	GO:0043412	macromolecule modification
0.35	GO:0044260	cellular macromolecule metabolic process

0.37	GO:0140096	catalytic activity, acting on a protein
0.37	GO:0005044	scavenger receptor activity
0.37	GO:0016787	hydrolase activity
0.36	GO:0030554	adenyl nucleotide binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0032555	purine ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0003676	nucleic acid binding
0.35	GO:0016740	transferase activity
0.35	GO:0030246	carbohydrate binding

0.49	GO:0036338	viral membrane
0.40	GO:0070701	mucus layer
0.37	GO:0005634	nucleus
0.36	GO:0000178	exosome (RNase complex)
0.35	GO:0055036	virion membrane
0.35	GO:0042600	chorion
0.34	GO:0070013	intracellular organelle lumen
0.34	GO:0000159	protein phosphatase type 2A complex
0.34	GO:0034708	methyltransferase complex
0.34	GO:0005774	vacuolar membrane

0.37

GO:0016787

tr|T1FUV7|T1FUV7_HELRO
Uncharacterized protein
Search

tr|T1FUV8|T1FUV8_HELRO
Uncharacterized protein
Search

tr|T1FUV9|T1FUV9_HELRO
Uncharacterized protein
Search

0.59	GO:0006352	DNA-templated transcription, initiation
0.50	GO:1903506	regulation of nucleic acid-templated transcription
0.50	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.49	GO:0010468	regulation of gene expression
0.39	GO:0006270	DNA replication initiation
0.39	GO:0008380	RNA splicing
0.39	GO:0007155	cell adhesion
0.38	GO:0006397	mRNA processing
0.37	GO:0006508	proteolysis

0.53	GO:0003700	DNA binding transcription factor activity
0.48	GO:0003677	DNA binding
0.43	GO:0050825	ice binding
0.39	GO:0004222	metalloendopeptidase activity
0.36	GO:0003723	RNA binding

0.43	GO:0020011	apicoplast
0.40	GO:0005681	spliceosomal complex
0.30	GO:0016020	membrane

0.39

GO:0004222

tr|T1FUW0|T1FUW0_HELRO
Isocitrate dehydrogenase [NADP]
Search

IDH1

0.49	Isocitrate dehydrogenase [NADP] cytoplasmic

0.81	GO:0006102	isocitrate metabolic process
0.64	GO:0006099	tricarboxylic acid cycle
0.41	GO:0030097	hemopoiesis
0.40	GO:0006103	2-oxoglutarate metabolic process
0.39	GO:0006979	response to oxidative stress
0.39	GO:0060696	regulation of phospholipid catabolic process
0.38	GO:0071071	regulation of phospholipid biosynthetic process
0.37	GO:0006749	glutathione metabolic process
0.37	GO:0070887	cellular response to chemical stimulus
0.36	GO:0033554	cellular response to stress

0.79	GO:0004450	isocitrate dehydrogenase (NADP+) activity
0.68	GO:0051287	NAD binding
0.64	GO:0000287	magnesium ion binding
0.40	GO:0045296	cadherin binding
0.39	GO:0042803	protein homodimerization activity
0.38	GO:0005102	receptor binding
0.32	GO:0003677	DNA binding

0.39	GO:0005777	peroxisome
0.38	GO:0005739	mitochondrion
0.38	GO:0005829	cytosol
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.79

EC:1.1.1.42

GO:0004450

tr|T1FUW1|T1FUW1_HELRO
Uncharacterized protein
Search

0.52	GO:0006817	phosphate ion transport
0.50	GO:0006468	protein phosphorylation
0.44	GO:0055085	transmembrane transport
0.42	GO:0006364	rRNA processing
0.41	GO:0006325	chromatin organization
0.39	GO:0032012	regulation of ARF protein signal transduction
0.38	GO:0018022	peptidyl-lysine methylation
0.37	GO:0042274	ribosomal small subunit biogenesis
0.37	GO:0065009	regulation of molecular function
0.36	GO:0006281	DNA repair

0.53	GO:0005315	inorganic phosphate transmembrane transporter activity
0.51	GO:0004672	protein kinase activity
0.45	GO:0032559	adenyl ribonucleotide binding
0.45	GO:0008144	drug binding
0.45	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0005199	structural constituent of cell wall
0.39	GO:0005086	ARF guanyl-nucleotide exchange factor activity
0.39	GO:0018024	histone-lysine N-methyltransferase activity
0.36	GO:0008080	N-acetyltransferase activity
0.36	GO:0016887	ATPase activity

0.46	GO:0032040	small-subunit processome
0.43	GO:0045095	keratin filament
0.39	GO:0031981	nuclear lumen
0.38	GO:0033202	DNA helicase complex
0.38	GO:0000785	chromatin
0.37	GO:0005887	integral component of plasma membrane
0.37	GO:1904949	ATPase complex

0.39

GO:0018024

tr|T1FUW2|T1FUW2_HELRO
Uncharacterized protein
Search

0.42	GO:0044265	cellular macromolecule catabolic process
0.42	GO:0018344	protein geranylgeranylation
0.41	GO:0006470	protein dephosphorylation
0.40	GO:0007264	small GTPase mediated signal transduction
0.40	GO:0006366	transcription by RNA polymerase II
0.40	GO:0045944	positive regulation of transcription by RNA polymerase II
0.39	GO:0030154	cell differentiation
0.39	GO:0009405	pathogenesis
0.39	GO:0030163	protein catabolic process
0.39	GO:0034655	nucleobase-containing compound catabolic process

0.43	GO:0030554	adenyl nucleotide binding
0.43	GO:0032555	purine ribonucleotide binding
0.43	GO:0008144	drug binding
0.43	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0001085	RNA polymerase II transcription factor binding
0.42	GO:0004722	protein serine/threonine phosphatase activity
0.42	GO:0005092	GDP-dissociation inhibitor activity
0.41	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.41	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.41	GO:0003682	chromatin binding

0.43	GO:0005634	nucleus
0.42	GO:0005968	Rab-protein geranylgeranyltransferase complex
0.40	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

0.40

GO:0003724

tr|T1FUW3|T1FUW3_HELRO
Uncharacterized protein
Search

0.43	GO:0006470	protein dephosphorylation
0.41	GO:0034968	histone lysine methylation
0.37	GO:0032774	RNA biosynthetic process
0.37	GO:0035171	lamellocyte differentiation
0.37	GO:0045612	positive regulation of hemocyte differentiation
0.37	GO:0060288	formation of a compartment boundary
0.37	GO:0045316	negative regulation of compound eye photoreceptor development
0.37	GO:0060289	compartment boundary maintenance
0.37	GO:0035172	hemocyte proliferation
0.37	GO:0042689	regulation of crystal cell differentiation

0.44	GO:0004722	protein serine/threonine phosphatase activity
0.41	GO:0018024	histone-lysine N-methyltransferase activity
0.40	GO:0003723	RNA binding
0.39	GO:0046872	metal ion binding
0.37	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.36	GO:0008504	monoamine transmembrane transporter activity
0.36	GO:0005351	sugar:proton symporter activity
0.36	GO:0017076	purine nucleotide binding
0.36	GO:0097367	carbohydrate derivative binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding

0.38	GO:0043231	intracellular membrane-bounded organelle
0.38	GO:0012505	endomembrane system
0.36	GO:0035003	subapical complex
0.36	GO:0044444	cytoplasmic part
0.35	GO:0005912	adherens junction
0.35	GO:0098588	bounding membrane of organelle
0.35	GO:0009986	cell surface
0.35	GO:0031984	organelle subcompartment
0.35	GO:0097708	intracellular vesicle
0.33	GO:0043234	protein complex

0.41

GO:0018024

tr|T1FUW4|T1FUW4_HELRO
Uncharacterized protein
Search

tr|T1FUW5|T1FUW5_HELRO
Uncharacterized protein
Search

tr|T1FUW6|T1FUW6_HELRO
Uncharacterized protein
Search

0.40	GO:0016311	dephosphorylation
0.40	GO:0030111	regulation of Wnt signaling pathway
0.40	GO:0098869	cellular oxidant detoxification
0.38	GO:0006644	phospholipid metabolic process
0.38	GO:0030258	lipid modification
0.36	GO:0090175	regulation of establishment of planar polarity
0.36	GO:0007165	signal transduction

0.43	GO:0008195	phosphatidate phosphatase activity
0.43	GO:0042577	lipid phosphatase activity
0.41	GO:0004601	peroxidase activity

0.37

GO:0005887

integral component of plasma membrane

0.43	EC:3.1.3.4	GO:0008195
0.41	KEGG:R03532	GO:0004601

tr|T1FUW7|T1FUW7_HELRO
Uncharacterized protein
Search

tr|T1FUW8|T1FUW8_HELRO
Uncharacterized protein
Search

tr|T1FUW9|T1FUW9_HELRO
Uncharacterized protein
Search

tr|T1FUX0|T1FUX0_HELRO
Uncharacterized protein
Search

0.77	GO:0000245	spliceosomal complex assembly
0.76	GO:0000387	spliceosomal snRNP assembly
0.47	GO:0048675	axon extension
0.37	GO:0060255	regulation of macromolecule metabolic process
0.37	GO:0080090	regulation of primary metabolic process
0.37	GO:0031323	regulation of cellular metabolic process
0.37	GO:0051171	regulation of nitrogen compound metabolic process
0.37	GO:0009889	regulation of biosynthetic process
0.36	GO:0035023	regulation of Rho protein signal transduction
0.35	GO:0007084	mitotic nuclear envelope reassembly

0.37	GO:0019899	enzyme binding
0.36	GO:0043565	sequence-specific DNA binding
0.36	GO:0003700	DNA binding transcription factor activity
0.35	GO:0098772	molecular function regulator
0.35	GO:0005199	structural constituent of cell wall
0.35	GO:0008241	peptidyl-dipeptidase activity
0.34	GO:0004180	carboxypeptidase activity
0.33	GO:0008237	metallopeptidase activity
0.33	GO:0016301	kinase activity
0.32	GO:0046872	metal ion binding

0.72	GO:0005681	spliceosomal complex
0.57	GO:0097504	Gemini of coiled bodies
0.56	GO:0032797	SMN complex
0.56	GO:0034719	SMN-Sm protein complex
0.49	GO:0005730	nucleolus
0.47	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.35

EC:3.4.15

GO:0008241

tr|T1FUX1|T1FUX1_HELRO
Uncharacterized protein
Search

tr|T1FUX2|T1FUX2_HELRO
Uncharacterized protein
Search

tr|T1FUX3|T1FUX3_HELRO
Uncharacterized protein
Search

0.51	GO:0016567	protein ubiquitination
0.42	GO:0000256	allantoin catabolic process
0.42	GO:2001141	regulation of RNA biosynthetic process
0.42	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.42	GO:0008608	attachment of spindle microtubules to kinetochore
0.42	GO:0000280	nuclear division
0.41	GO:0010468	regulation of gene expression
0.41	GO:0051983	regulation of chromosome segregation
0.40	GO:0000819	sister chromatid segregation
0.40	GO:1903047	mitotic cell cycle process

0.52	GO:0004842	ubiquitin-protein transferase activity
0.43	GO:0004037	allantoicase activity
0.43	GO:0003700	DNA binding transcription factor activity
0.40	GO:0016772	transferase activity, transferring phosphorus-containing groups
0.39	GO:0003676	nucleic acid binding
0.38	GO:0043130	ubiquitin binding
0.37	GO:0061659	ubiquitin-like protein ligase activity
0.36	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity
0.36	GO:0017076	purine nucleotide binding
0.36	GO:0097367	carbohydrate derivative binding

0.41	GO:0000776	kinetochore
0.40	GO:1990298	bub1-bub3 complex
0.39	GO:0033597	mitotic checkpoint complex
0.36	GO:0031981	nuclear lumen
0.36	GO:0020011	apicoplast
0.35	GO:0055029	nuclear DNA-directed RNA polymerase complex
0.34	GO:0005829	cytosol
0.34	GO:0005739	mitochondrion
0.34	GO:0005840	ribosome
0.34	GO:0005576	extracellular region

0.43	EC:3.5.3.4	GO:0004037
0.52	KEGG:R03876	GO:0004842

tr|T1FUX4|T1FUX4_HELRO
Uncharacterized protein
Search

0.44	GO:0060446	branching involved in open tracheal system development
0.42	GO:0048523	negative regulation of cellular process
0.42	GO:0045664	regulation of neuron differentiation
0.42	GO:0040029	regulation of gene expression, epigenetic
0.41	GO:0009887	animal organ morphogenesis
0.41	GO:0048102	autophagic cell death
0.41	GO:0048468	cell development
0.41	GO:0060033	anatomical structure regression
0.41	GO:1903429	regulation of cell maturation
0.40	GO:2001141	regulation of RNA biosynthetic process

0.41	GO:0003700	DNA binding transcription factor activity
0.38	GO:0001085	RNA polymerase II transcription factor binding
0.38	GO:0003688	DNA replication origin binding
0.38	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.37	GO:0003682	chromatin binding
0.37	GO:0005200	structural constituent of cytoskeleton
0.36	GO:0046983	protein dimerization activity
0.36	GO:0008080	N-acetyltransferase activity

0.39	GO:0030425	dendrite
0.39	GO:0030424	axon
0.39	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0005634	nucleus
0.38	GO:0000178	exosome (RNase complex)
0.37	GO:0005819	spindle
0.36	GO:0005829	cytosol
0.36	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.36

GO:0008080

tr|T1FUX5|T1FUX5_HELRO
Uncharacterized protein
Search

tr|T1FUX6|T1FUX6_HELRO
Uncharacterized protein
Search

0.10	Venom allergen

0.35	GO:0007339	binding of sperm to zona pellucida
0.35	GO:0043086	negative regulation of catalytic activity
0.35	GO:0032269	negative regulation of cellular protein metabolic process
0.34	GO:0052547	regulation of peptidase activity
0.34	GO:0007050	cell cycle arrest
0.34	GO:0060325	face morphogenesis
0.33	GO:0071900	regulation of protein serine/threonine kinase activity
0.33	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.33	GO:0042326	negative regulation of phosphorylation
0.33	GO:0006508	proteolysis

0.35	GO:0004857	enzyme inhibitor activity
0.34	GO:0061134	peptidase regulator activity
0.34	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity
0.34	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.33	GO:0008233	peptidase activity
0.33	GO:0005509	calcium ion binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.66	GO:0005576	extracellular region
0.36	GO:0097224	sperm connecting piece
0.35	GO:0031982	vesicle
0.34	GO:0012505	endomembrane system
0.34	GO:0045121	membrane raft
0.33	GO:0043229	intracellular organelle
0.33	GO:0044444	cytoplasmic part
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.34

GO:0016538

tr|T1FUX7|T1FUX7_HELRO
Uncharacterized protein
Search

0.48	GO:0043968	histone H2A acetylation
0.48	GO:0043967	histone H4 acetylation
0.43	GO:0002244	hematopoietic progenitor cell differentiation
0.36	GO:0045944	positive regulation of transcription by RNA polymerase II
0.35	GO:0040008	regulation of growth
0.34	GO:0030522	intracellular receptor signaling pathway
0.33	GO:0007166	cell surface receptor signaling pathway
0.33	GO:0006351	transcription, DNA-templated

0.34	GO:0004887	thyroid hormone receptor activity
0.33	GO:0005515	protein binding

0.83	GO:0000812	Swr1 complex
0.79	GO:0035267	NuA4 histone acetyltransferase complex
0.41	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

tr|T1FUX8|T1FUX8_HELRO
Uncharacterized protein
Search

tr|T1FUX9|T1FUX9_HELRO
Uncharacterized protein
Search

tr|T1FUY0|T1FUY0_HELRO
Uncharacterized protein
Search

tr|T1FUY1|T1FUY1_HELRO
Uncharacterized protein
Search

tr|T1FUY2|T1FUY2_HELRO
Uncharacterized protein
Search

0.72	GO:0006898	receptor-mediated endocytosis
0.33	GO:0032259	methylation

0.81	GO:0005044	scavenger receptor activity
0.41	GO:0030246	carbohydrate binding
0.33	GO:0008168	methyltransferase activity

0.30

GO:0031224

intrinsic component of membrane

0.33

GO:0008168

tr|T1FUY3|T1FUY3_HELRO
Uncharacterized protein
Search

tr|T1FUY4|T1FUY4_HELRO
Uncharacterized protein
Search

0.43	GO:0055085	transmembrane transport
0.39	GO:0006338	chromatin remodeling
0.39	GO:0016070	RNA metabolic process
0.39	GO:0010467	gene expression
0.38	GO:0050794	regulation of cellular process
0.38	GO:0009059	macromolecule biosynthetic process
0.38	GO:0034654	nucleobase-containing compound biosynthetic process
0.38	GO:0044260	cellular macromolecule metabolic process
0.37	GO:0051641	cellular localization
0.37	GO:0010556	regulation of macromolecule biosynthetic process

0.39	GO:0003676	nucleic acid binding
0.38	GO:0003712	transcription cofactor activity
0.38	GO:0043168	anion binding
0.37	GO:1901567	fatty acid derivative binding
0.37	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.37	GO:1901681	sulfur compound binding
0.37	GO:0017076	purine nucleotide binding
0.37	GO:0097367	carbohydrate derivative binding
0.37	GO:0008144	drug binding
0.37	GO:0140096	catalytic activity, acting on a protein

0.42	GO:0031981	nuclear lumen
0.40	GO:0090575	RNA polymerase II transcription factor complex
0.39	GO:0055029	nuclear DNA-directed RNA polymerase complex
0.37	GO:0005694	chromosome
0.36	GO:0033202	DNA helicase complex
0.35	GO:0031248	protein acetyltransferase complex
0.35	GO:0032040	small-subunit processome
0.35	GO:0015934	large ribosomal subunit
0.35	GO:1905368	peptidase complex
0.35	GO:1904949	ATPase complex

0.36

EC:2.7

GO:0016772

tr|T1FUY5|T1FUY5_HELRO
Uncharacterized protein
Search

0.48	GO:0007165	signal transduction
0.45	GO:0006468	protein phosphorylation
0.39	GO:0018212	peptidyl-tyrosine modification
0.37	GO:0016570	histone modification
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:0010468	regulation of gene expression
0.36	GO:0051726	regulation of cell cycle
0.36	GO:0018022	peptidyl-lysine methylation
0.35	GO:0006368	transcription elongation from RNA polymerase II promoter

0.45	GO:0004672	protein kinase activity
0.44	GO:0032559	adenyl ribonucleotide binding
0.44	GO:0008144	drug binding
0.44	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0003700	DNA binding transcription factor activity
0.36	GO:0008270	zinc ion binding
0.36	GO:0046983	protein dimerization activity
0.36	GO:0003676	nucleic acid binding
0.36	GO:0018024	histone-lysine N-methyltransferase activity
0.36	GO:0004087	carbamoyl-phosphate synthase (ammonia) activity

0.37	GO:0016591	DNA-directed RNA polymerase II, holoenzyme
0.35	GO:0008023	transcription elongation factor complex
0.35	GO:0005871	kinesin complex
0.34	GO:0000781	chromosome, telomeric region
0.30	GO:0016020	membrane

0.36	EC:2.1.1.43	GO:0018024
0.36	KEGG:R00149	GO:0004087

tr|T1FUY6|T1FUY6_HELRO
Uncharacterized protein
Search

tr|T1FUY7|T1FUY7_HELRO
DNA polymerase
Search

POLA1

0.41	DNA polymerase

0.67	GO:0071897	DNA biosynthetic process
0.66	GO:0006260	DNA replication
0.63	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.49	GO:0022616	DNA strand elongation
0.48	GO:0006303	double-strand break repair via nonhomologous end joining
0.39	GO:0016070	RNA metabolic process
0.36	GO:1903046	meiotic cell cycle process
0.33	GO:0070914	UV-damage excision repair
0.32	GO:0008283	cell proliferation

0.72	GO:0008408	3'-5' exonuclease activity
0.71	GO:0003887	DNA-directed DNA polymerase activity
0.65	GO:0051539	4 iron, 4 sulfur cluster binding
0.64	GO:0001882	nucleoside binding
0.55	GO:0003677	DNA binding
0.53	GO:0046872	metal ion binding
0.53	GO:1901265	nucleoside phosphate binding
0.43	GO:0046982	protein heterodimerization activity
0.36	GO:0003896	DNA primase activity
0.32	GO:0019901	protein kinase binding

0.60	GO:0005634	nucleus
0.50	GO:0000428	DNA-directed RNA polymerase complex
0.50	GO:0030894	replisome
0.47	GO:0031974	membrane-enclosed lumen
0.42	GO:0005829	cytosol
0.32	GO:0000785	chromatin
0.32	GO:0012505	endomembrane system
0.32	GO:0031967	organelle envelope

0.71

EC:2.7.7.7

GO:0003887

tr|T1FUY8|T1FUY8_HELRO
Uncharacterized protein
Search

NELFB

0.93	Negative elongation factor complex member B

0.72	GO:0045892	negative regulation of transcription, DNA-templated
0.56	GO:0006414	translational elongation
0.46	GO:0034243	regulation of transcription elongation from RNA polymerase II promoter
0.42	GO:1902038	positive regulation of hematopoietic stem cell differentiation
0.40	GO:0045944	positive regulation of transcription by RNA polymerase II
0.34	GO:0006368	transcription elongation from RNA polymerase II promoter
0.34	GO:0050434	positive regulation of viral transcription
0.32	GO:0007165	signal transduction

0.56	GO:0003746	translation elongation factor activity
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.45	GO:0031974	membrane-enclosed lumen
0.41	GO:0044446	intracellular organelle part
0.39	GO:0043234	protein complex
0.34	GO:0017053	transcriptional repressor complex
0.33	GO:0005694	chromosome
0.32	GO:0005737	cytoplasm

tr|T1FUY9|T1FUY9_HELRO
Uncharacterized protein
Search

DNAJC2

0.83	Putative ribosome-associated chaperone zuotin translation

0.50	GO:2000279	negative regulation of DNA biosynthetic process
0.46	GO:0045893	positive regulation of transcription, DNA-templated
0.43	GO:0006260	DNA replication
0.38	GO:0016569	covalent chromatin modification
0.35	GO:0006351	transcription, DNA-templated
0.35	GO:1900034	regulation of cellular response to heat
0.35	GO:0051083	'de novo' cotranslational protein folding
0.34	GO:0032781	positive regulation of ATPase activity
0.33	GO:0006468	protein phosphorylation

0.55	GO:0003677	DNA binding
0.54	GO:0061649	ubiquitin modification-dependent histone binding
0.51	GO:0030544	Hsp70 protein binding
0.48	GO:0003682	chromatin binding
0.34	GO:0001671	ATPase activator activity
0.33	GO:0004672	protein kinase activity
0.33	GO:0003723	RNA binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.58	GO:0005634	nucleus
0.45	GO:0005829	cytosol
0.43	GO:0012505	endomembrane system
0.41	GO:0031967	organelle envelope
0.41	GO:0031090	organelle membrane
0.33	GO:0043233	organelle lumen
0.30	GO:0031224	intrinsic component of membrane

tr|T1FUZ0|T1FUZ0_HELRO
Uncharacterized protein
Search

0.11	DNA repair protein REV1

0.72	GO:0042276	error-prone translesion synthesis
0.38	GO:0009411	response to UV
0.35	GO:0016180	snRNA processing
0.34	GO:0006508	proteolysis
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression
0.32	GO:0016310	phosphorylation

0.67	GO:0003684	damaged DNA binding
0.55	GO:0016779	nucleotidyltransferase activity
0.35	GO:0004222	metalloendopeptidase activity
0.34	GO:0016757	transferase activity, transferring glycosyl groups
0.34	GO:0043565	sequence-specific DNA binding
0.34	GO:0003700	DNA binding transcription factor activity
0.33	GO:0005515	protein binding
0.33	GO:0046872	metal ion binding
0.32	GO:0016301	kinase activity

0.52	GO:0005634	nucleus
0.34	GO:0000428	DNA-directed RNA polymerase complex
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0043234	protein complex
0.33	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.55

GO:0016779

tr|T1FUZ1|T1FUZ1_HELRO
Uncharacterized protein
Search

tr|T1FUZ2|T1FUZ2_HELRO
Uncharacterized protein
Search

0.81	GO:0018344	protein geranylgeranylation
0.39	GO:0005975	carbohydrate metabolic process
0.34	GO:0043687	post-translational protein modification
0.34	GO:0007601	visual perception
0.34	GO:0042981	regulation of apoptotic process
0.33	GO:0006298	mismatch repair
0.33	GO:0006461	protein complex assembly
0.33	GO:0006468	protein phosphorylation
0.33	GO:0055114	oxidation-reduction process
0.32	GO:0016579	protein deubiquitination

0.84	GO:0004663	Rab geranylgeranyltransferase activity
0.42	GO:0030246	carbohydrate binding
0.41	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.37	GO:0017137	Rab GTPase binding
0.35	GO:0008270	zinc ion binding
0.35	GO:0003995	acyl-CoA dehydrogenase activity
0.34	GO:0019840	isoprenoid binding
0.34	GO:0050660	flavin adenine dinucleotide binding
0.34	GO:0046982	protein heterodimerization activity
0.33	GO:0030983	mismatched DNA binding

0.47	GO:0005968	Rab-protein geranylgeranyltransferase complex
0.33	GO:0005829	cytosol
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.84

EC:2.5.1.60

GO:0004663

tr|T1FUZ3|T1FUZ3_HELRO
Uncharacterized protein
Search

0.40	GO:0009190	cyclic nucleotide biosynthetic process
0.38	GO:0007039	protein catabolic process in the vacuole
0.38	GO:0006325	chromatin organization
0.38	GO:0043547	positive regulation of GTPase activity
0.38	GO:0007154	cell communication
0.38	GO:0050789	regulation of biological process
0.38	GO:0046856	phosphatidylinositol dephosphorylation
0.38	GO:0051716	cellular response to stimulus
0.37	GO:0006986	response to unfolded protein
0.37	GO:0046058	cAMP metabolic process

0.40	GO:0016849	phosphorus-oxygen lyase activity
0.38	GO:0050825	ice binding
0.38	GO:0005096	GTPase activator activity
0.37	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.37	GO:0003700	DNA binding transcription factor activity
0.37	GO:0009975	cyclase activity
0.36	GO:0003677	DNA binding
0.36	GO:0004527	exonuclease activity
0.36	GO:0008017	microtubule binding
0.36	GO:0042578	phosphoric ester hydrolase activity

0.73	GO:0005680	anaphase-promoting complex
0.37	GO:0070603	SWI/SNF superfamily-type complex
0.36	GO:0005773	vacuole
0.36	GO:0005874	microtubule
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.40

EC:4.6

GO:0016849

tr|T1FUZ4|T1FUZ4_HELRO
Uncharacterized protein
Search

tr|T1FUZ5|T1FUZ5_HELRO
Palmitoyltransferase
Search

0.33	Palmitoyltransferase

0.35	GO:0018345	protein palmitoylation
0.34	GO:0006508	proteolysis

0.79	GO:0019706	protein-cysteine S-palmitoyltransferase activity
0.35	GO:0004252	serine-type endopeptidase activity

0.36	GO:0005774	vacuolar membrane
0.34	GO:0005794	Golgi apparatus
0.34	GO:0005783	endoplasmic reticulum
0.30	GO:0044425	membrane part

0.79

GO:0019706

tr|T1FUZ6|T1FUZ6_HELRO
Uncharacterized protein
Search

tr|T1FUZ7|T1FUZ7_HELRO
Uncharacterized protein
Search

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding

tr|T1FUZ8|T1FUZ8_HELRO
Uncharacterized protein
Search

0.42	GO:0051568	histone H3-K4 methylation
0.37	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway
0.36	GO:0043627	response to estrogen
0.36	GO:0005992	trehalose biosynthetic process
0.36	GO:1903013	response to differentiation-inducing factor 1
0.36	GO:0016573	histone acetylation
0.36	GO:0006357	regulation of transcription by RNA polymerase II
0.36	GO:0006338	chromatin remodeling
0.36	GO:0007162	negative regulation of cell adhesion
0.35	GO:0008284	positive regulation of cell proliferation

0.47	GO:0003676	nucleic acid binding
0.42	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.40	GO:0045735	nutrient reservoir activity
0.37	GO:0046872	metal ion binding
0.36	GO:0005515	protein binding
0.35	GO:0004386	helicase activity
0.35	GO:0016407	acetyltransferase activity
0.35	GO:0008452	RNA ligase activity
0.34	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.34	GO:0070403	NAD+ binding

0.42	GO:0005654	nucleoplasm
0.41	GO:0034708	methyltransferase complex
0.38	GO:0031248	protein acetyltransferase complex
0.36	GO:0090575	RNA polymerase II transcription factor complex
0.35	GO:0055029	nuclear DNA-directed RNA polymerase complex
0.35	GO:0005640	nuclear outer membrane
0.35	GO:1905368	peptidase complex
0.35	GO:0005637	nuclear inner membrane
0.34	GO:0005813	centrosome
0.33	GO:0005886	plasma membrane

0.35

GO:0016407

tr|T1FUZ9|T1FUZ9_HELRO
Uncharacterized protein
Search

0.55	GO:0006396	RNA processing
0.40	GO:0060255	regulation of macromolecule metabolic process
0.39	GO:0031326	regulation of cellular biosynthetic process
0.39	GO:0051171	regulation of nitrogen compound metabolic process
0.39	GO:0080090	regulation of primary metabolic process
0.38	GO:0043412	macromolecule modification
0.37	GO:0044267	cellular protein metabolic process
0.37	GO:0007275	multicellular organism development
0.37	GO:0016310	phosphorylation
0.36	GO:0023056	positive regulation of signaling

0.40	GO:0140110	transcription regulator activity
0.38	GO:0008270	zinc ion binding
0.38	GO:0003676	nucleic acid binding
0.38	GO:0140096	catalytic activity, acting on a protein
0.37	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.37	GO:0016301	kinase activity
0.37	GO:0005515	protein binding
0.36	GO:0030554	adenyl nucleotide binding
0.36	GO:0097367	carbohydrate derivative binding
0.36	GO:0008144	drug binding

0.39	GO:0005634	nucleus
0.36	GO:0070013	intracellular organelle lumen
0.36	GO:0032991	macromolecular complex
0.36	GO:0043232	intracellular non-membrane-bounded organelle
0.35	GO:0044446	intracellular organelle part
0.35	GO:0098831	presynaptic active zone cytoplasmic component
0.34	GO:0060293	germ plasm
0.33	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.37

GO:0016773

tr|T1FV00|T1FV00_HELRO
Uncharacterized protein
Search

tr|T1FV01|T1FV01_HELRO
Uncharacterized protein
Search

tr|T1FV02|T1FV02_HELRO
Uncharacterized protein
Search

tr|T1FV03|T1FV03_HELRO
Uncharacterized protein
Search

tr|T1FV04|T1FV04_HELRO
Uncharacterized protein
Search

0.43	GO:0043044	ATP-dependent chromatin remodeling
0.43	GO:0019432	triglyceride biosynthetic process
0.41	GO:0043412	macromolecule modification
0.40	GO:0044267	cellular protein metabolic process
0.38	GO:0016310	phosphorylation
0.38	GO:0065007	biological regulation
0.37	GO:0016070	RNA metabolic process
0.36	GO:0006913	nucleocytoplasmic transport
0.36	GO:0000973	posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery
0.36	GO:0034398	telomere tethering at nuclear periphery

0.43	GO:0004144	diacylglycerol O-acyltransferase activity
0.41	GO:0003676	nucleic acid binding
0.41	GO:0030554	adenyl nucleotide binding
0.40	GO:0097367	carbohydrate derivative binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0008144	drug binding
0.40	GO:0140096	catalytic activity, acting on a protein
0.39	GO:0016301	kinase activity
0.39	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.38	GO:0003700	DNA binding transcription factor activity

0.40	GO:0012505	endomembrane system
0.40	GO:0043231	intracellular membrane-bounded organelle
0.39	GO:0031984	organelle subcompartment
0.37	GO:0044444	cytoplasmic part
0.36	GO:0043234	protein complex
0.35	GO:0043232	intracellular non-membrane-bounded organelle
0.34	GO:0031967	organelle envelope
0.34	GO:1902494	catalytic complex
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0070013	intracellular organelle lumen

0.43

EC:2.3.1.20

GO:0004144

tr|T1FV05|T1FV05_HELRO
Uncharacterized protein
Search

0.58	Inositol polyphosphate 5-phosphatase K

0.81	GO:0046856	phosphatidylinositol dephosphorylation
0.45	GO:0098529	neuromuscular junction development, skeletal muscle fiber
0.42	GO:0002088	lens development in camera-type eye
0.42	GO:0061053	somite development
0.37	GO:0120031	plasma membrane bounded cell projection assembly
0.37	GO:2001153	positive regulation of renal water transport
0.37	GO:2000466	negative regulation of glycogen (starch) synthase activity
0.37	GO:0010243	response to organonitrogen compound
0.37	GO:0045869	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate
0.37	GO:0014070	response to organic cyclic compound

0.51	GO:0016787	hydrolase activity
0.36	GO:0005000	vasopressin receptor activity
0.32	GO:0005509	calcium ion binding

0.36	GO:0032587	ruffle membrane
0.35	GO:0005802	trans-Golgi network
0.35	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0043005	neuron projection
0.34	GO:0005783	endoplasmic reticulum
0.34	GO:0005829	cytosol
0.34	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.51

GO:0016787

tr|T1FV06|T1FV06_HELRO
Uncharacterized protein
Search

tr|T1FV07|T1FV07_HELRO
Uncharacterized protein
Search

0.46	GO:0006366	transcription by RNA polymerase II
0.45	GO:0031323	regulation of cellular metabolic process
0.45	GO:0051171	regulation of nitrogen compound metabolic process
0.45	GO:0060255	regulation of macromolecule metabolic process
0.45	GO:0080090	regulation of primary metabolic process
0.44	GO:0009889	regulation of biosynthetic process
0.43	GO:0009966	regulation of signal transduction
0.42	GO:0007275	multicellular organism development
0.42	GO:0036211	protein modification process
0.41	GO:0023056	positive regulation of signaling

0.48	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.48	GO:0000987	proximal promoter sequence-specific DNA binding
0.45	GO:0140110	transcription regulator activity
0.42	GO:0005515	protein binding
0.42	GO:0060090	molecular adaptor activity
0.41	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.40	GO:0004672	protein kinase activity
0.39	GO:0016874	ligase activity
0.39	GO:0017076	purine nucleotide binding
0.39	GO:0097367	carbohydrate derivative binding

0.44	GO:0005634	nucleus
0.42	GO:0070013	intracellular organelle lumen
0.41	GO:0034708	methyltransferase complex
0.39	GO:0044446	intracellular organelle part
0.38	GO:0032040	small-subunit processome
0.37	GO:0043234	protein complex
0.36	GO:0005891	voltage-gated calcium channel complex
0.36	GO:0031248	protein acetyltransferase complex
0.36	GO:1905368	peptidase complex
0.35	GO:0005783	endoplasmic reticulum

0.39

GO:0016874

tr|T1FV08|T1FV08_HELRO
Uncharacterized protein
Search

0.43	GO:0007016	cytoskeletal anchoring at plasma membrane
0.40	GO:0007155	cell adhesion

0.74	GO:0003779	actin binding
0.41	GO:0005200	structural constituent of cytoskeleton
0.41	GO:0032403	protein complex binding

0.43	GO:0001726	ruffle
0.42	GO:0005925	focal adhesion
0.39	GO:0005856	cytoskeleton

tr|T1FV09|T1FV09_HELRO
Uncharacterized protein
Search

tr|T1FV10|T1FV10_HELRO
Uncharacterized protein
Search

0.61	Transcription factor IIIB subunit

0.82	GO:0006359	regulation of transcription by RNA polymerase III
0.81	GO:0070897	DNA-templated transcriptional preinitiation complex assembly
0.80	GO:0006383	transcription by RNA polymerase III
0.40	GO:0006413	translational initiation
0.37	GO:0090074	negative regulation of protein homodimerization activity
0.37	GO:0070893	transposon integration
0.37	GO:0001120	protein-DNA complex remodeling
0.35	GO:0045893	positive regulation of transcription, DNA-templated
0.34	GO:0000387	spliceosomal snRNP assembly
0.34	GO:0042176	regulation of protein catabolic process

0.84	GO:0001026	TFIIIB-type transcription factor activity
0.82	GO:0017025	TBP-class protein binding
0.43	GO:0046872	metal ion binding
0.40	GO:0003743	translation initiation factor activity
0.37	GO:0000994	RNA polymerase III core binding
0.37	GO:0001156	TFIIIC-class transcription factor binding
0.37	GO:0001006	RNA polymerase III type 3 promoter sequence-specific DNA binding
0.33	GO:0030234	enzyme regulator activity

0.83	GO:0000126	transcription factor TFIIIB complex
0.33	GO:1905369	endopeptidase complex
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0031224	intrinsic component of membrane

tr|T1FV11|T1FV11_HELRO
Uncharacterized protein
Search

tr|T1FV12|T1FV12_HELRO
Uncharacterized protein
Search

0.61	GO:0006508	proteolysis
0.52	GO:0050435	amyloid-beta metabolic process
0.37	GO:0007416	synapse assembly
0.35	GO:0051289	protein homotetramerization
0.34	GO:0043312	neutrophil degranulation
0.33	GO:0006415	translational termination
0.33	GO:0006303	double-strand break repair via nonhomologous end joining
0.33	GO:0000723	telomere maintenance
0.31	GO:0055114	oxidation-reduction process

0.67	GO:0017171	serine hydrolase activity
0.62	GO:0070011	peptidase activity, acting on L-amino acid peptides
0.46	GO:0042802	identical protein binding
0.33	GO:0042162	telomeric DNA binding
0.33	GO:0003723	RNA binding
0.33	GO:0046872	metal ion binding
0.33	GO:0003684	damaged DNA binding
0.32	GO:0050660	flavin adenine dinucleotide binding
0.32	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors

0.48	GO:0031965	nuclear membrane
0.44	GO:0005829	cytosol
0.36	GO:0048786	presynaptic active zone
0.35	GO:0070062	extracellular exosome
0.35	GO:1904813	ficolin-1-rich granule lumen
0.34	GO:0005773	vacuole
0.33	GO:0009507	chloroplast
0.33	GO:0043564	Ku70:Ku80 complex

0.32

EC:1.1

GO:0016614

tr|T1FV13|T1FV13_HELRO
Uncharacterized protein
Search

tr|T1FV14|T1FV14_HELRO
Uncharacterized protein
Search

0.47	DNA-directed RNA polymerase I/III subunit

0.62

GO:0006366

transcription by RNA polymerase II

0.70	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.68	GO:0046983	protein dimerization activity
0.50	GO:0003677	DNA binding

0.66

GO:0005665

DNA-directed RNA polymerase II, core complex

0.70

GO:0003899

tr|T1FV15|T1FV15_HELRO
Uncharacterized protein
Search

0.34	GO:0017187	peptidyl-glutamic acid carboxylation
0.34	GO:0007155	cell adhesion

0.61	GO:0016887	ATPase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0008488	gamma-glutamyl carboxylase activity

0.42	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.61

GO:0016887

tr|T1FV16|T1FV16_HELRO
Uncharacterized protein
Search

tr|T1FV17|T1FV17_HELRO
Uncharacterized protein
Search

0.37	GO:0032259	methylation
0.36	GO:0043547	positive regulation of GTPase activity

0.75	GO:0047429	nucleoside-triphosphate diphosphatase activity
0.37	GO:0008168	methyltransferase activity
0.36	GO:0005096	GTPase activator activity
0.33	GO:0046872	metal ion binding

0.45

GO:0005737

cytoplasm

0.75

EC:3.6.1.19

GO:0047429

tr|T1FV18|T1FV18_HELRO
Uncharacterized protein
Search

0.77	GO:0035023	regulation of Rho protein signal transduction
0.66	GO:0065009	regulation of molecular function
0.62	GO:0007264	small GTPase mediated signal transduction
0.52	GO:0008361	regulation of cell size
0.50	GO:0016477	cell migration
0.50	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity
0.48	GO:0006909	phagocytosis
0.48	GO:0030217	T cell differentiation
0.47	GO:0007229	integrin-mediated signaling pathway
0.46	GO:0045785	positive regulation of cell adhesion

0.78	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.54	GO:0001784	phosphotyrosine residue binding
0.52	GO:0046872	metal ion binding
0.49	GO:0048365	Rac GTPase binding
0.45	GO:0005154	epidermal growth factor receptor binding
0.35	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.34	GO:0004697	protein kinase C activity
0.33	GO:0016491	oxidoreductase activity
0.33	GO:0140110	transcription regulator activity
0.33	GO:0008830	dTDP-4-dehydrorhamnose 3,5-epimerase activity

0.46	GO:0005911	cell-cell junction
0.45	GO:0005622	intracellular
0.37	GO:0005886	plasma membrane
0.33	GO:1902493	acetyltransferase complex
0.32	GO:1905368	peptidase complex
0.32	GO:0012505	endomembrane system
0.32	GO:0031974	membrane-enclosed lumen
0.32	GO:0031975	envelope
0.32	GO:0043234	protein complex
0.32	GO:0044422	organelle part

0.35	EC:2.7.1.153	GO:0046934
0.35	KEGG:R04545	GO:0046934

tr|T1FV19|T1FV19_HELRO
Uncharacterized protein
Search

tr|T1FV20|T1FV20_HELRO
Uncharacterized protein
Search

tr|T1FV21|T1FV21_HELRO
Uncharacterized protein
Search

0.32	Glutamine amidotransferase

0.54	GO:0006508	proteolysis
0.46	GO:0006541	glutamine metabolic process
0.32	GO:0055114	oxidation-reduction process

0.55	GO:0008233	peptidase activity
0.39	GO:0016798	hydrolase activity, acting on glycosyl bonds
0.38	GO:0016740	transferase activity
0.33	GO:0004462	lactoylglutathione lyase activity
0.32	GO:0016491	oxidoreductase activity
0.32	GO:0046872	metal ion binding

0.30

GO:0031224

intrinsic component of membrane

0.55	EC:3.4	GO:0008233
0.33	KEGG:R02530	GO:0004462

tr|T1FV22|T1FV22_HELRO
Uncharacterized protein
Search

tr|T1FV23|T1FV23_HELRO
Uncharacterized protein
Search

0.50	GO:0043231	intracellular membrane-bounded organelle
0.49	GO:0005737	cytoplasm

tr|T1FV24|T1FV24_HELRO
Uncharacterized protein
Search

tr|T1FV25|T1FV25_HELRO
Uncharacterized protein
Search

0.21	Aminopeptidase

0.63	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I
0.61	GO:0006508	proteolysis
0.53	GO:0008217	regulation of blood pressure
0.41	GO:0043171	peptide catabolic process
0.39	GO:0060177	regulation of angiotensin metabolic process
0.38	GO:0050886	endocrine process
0.38	GO:0007267	cell-cell signaling
0.37	GO:0042445	hormone metabolic process
0.36	GO:0051604	protein maturation
0.35	GO:0002250	adaptive immune response

0.69	GO:0004177	aminopeptidase activity
0.67	GO:0008237	metallopeptidase activity
0.63	GO:0008270	zinc ion binding
0.42	GO:0042277	peptide binding
0.33	GO:0004175	endopeptidase activity
0.33	GO:0010181	FMN binding
0.33	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.32	GO:0051287	NAD binding
0.32	GO:0051539	4 iron, 4 sulfur cluster binding
0.32	GO:0003676	nucleic acid binding

0.53	GO:0005783	endoplasmic reticulum
0.46	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.45	GO:0031984	organelle subcompartment
0.35	GO:0005886	plasma membrane
0.33	GO:0043233	organelle lumen
0.30	GO:0016021	integral component of membrane

0.69

EC:3.4.11

GO:0004177

tr|T1FV26|T1FV26_HELRO
Uncharacterized protein
Search

0.10	O-acyltransferase

0.75	GO:0019432	triglyceride biosynthetic process
0.57	GO:0055088	lipid homeostasis
0.56	GO:0034379	very-low-density lipoprotein particle assembly
0.55	GO:0034435	cholesterol esterification
0.52	GO:0019915	lipid storage
0.50	GO:0046339	diacylglycerol metabolic process
0.49	GO:0035336	long-chain fatty-acyl-CoA metabolic process
0.47	GO:0055081	anion homeostasis
0.46	GO:0042986	positive regulation of amyloid precursor protein biosynthetic process
0.45	GO:0010742	macrophage derived foam cell differentiation

0.74	GO:0008374	O-acyltransferase activity
0.43	GO:0015485	cholesterol binding
0.43	GO:0000062	fatty-acyl-CoA binding
0.36	GO:0004325	ferrochelatase activity
0.36	GO:0103095	wax ester synthase activity
0.36	GO:0102966	arachidoyl-CoA:1-dodecanol O-acyltransferase activity
0.35	GO:0005504	fatty acid binding
0.34	GO:0019992	diacylglycerol binding
0.33	GO:0005515	protein binding
0.32	GO:0004252	serine-type endopeptidase activity

0.66	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0035579	specific granule membrane
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.74	EC:2.3.1	GO:0008374
0.36	KEGG:R00310	GO:0004325

tr|T1FV27|T1FV27_HELRO
Uncharacterized protein
Search

0.52	GO:0006508	proteolysis
0.47	GO:0017186	peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase
0.33	GO:0001172	transcription, RNA-templated
0.33	GO:0006468	protein phosphorylation

0.82	GO:0016603	glutaminyl-peptide cyclotransferase activity
0.52	GO:0008233	peptidase activity
0.48	GO:0046872	metal ion binding
0.33	GO:0003968	RNA-directed 5'-3' RNA polymerase activity
0.33	GO:0004672	protein kinase activity
0.32	GO:0003723	RNA binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.39	GO:0005794	Golgi apparatus
0.38	GO:0005576	extracellular region
0.37	GO:0005739	mitochondrion
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.82

EC:2.3.2.5

GO:0016603

tr|T1FV28|T1FV28_HELRO
DNA-directed RNA polymerase subunit
Search

POLR2A

0.49	DNA-directed RNA polymerase subunit

0.71	GO:0006366	transcription by RNA polymerase II
0.42	GO:2000543	positive regulation of gastrulation
0.42	GO:0009299	mRNA transcription
0.41	GO:0051254	positive regulation of RNA metabolic process
0.41	GO:0010628	positive regulation of gene expression
0.40	GO:0007369	gastrulation
0.40	GO:0009792	embryo development ending in birth or egg hatching
0.39	GO:0010557	positive regulation of macromolecule biosynthetic process
0.38	GO:0031328	positive regulation of cellular biosynthetic process
0.38	GO:0043484	regulation of RNA splicing

0.70	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.55	GO:0003677	DNA binding
0.47	GO:0001067	regulatory region nucleic acid binding
0.37	GO:0031625	ubiquitin protein ligase binding
0.35	GO:0046872	metal ion binding
0.33	GO:0003723	RNA binding
0.33	GO:0003968	RNA-directed 5'-3' RNA polymerase activity
0.32	GO:0005524	ATP binding
0.32	GO:0016491	oxidoreductase activity

0.76	GO:0005665	DNA-directed RNA polymerase II, core complex
0.50	GO:0005719	nuclear euchromatin
0.41	GO:0035327	transcriptionally active chromatin
0.39	GO:0000974	Prp19 complex
0.36	GO:0005730	nucleolus
0.33	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.70

GO:0003899

tr|T1FV29|T1FV29_HELRO
Uncharacterized protein
Search

tr|T1FV30|T1FV30_HELRO
Uncharacterized protein
Search

tr|T1FV31|T1FV31_HELRO
Uncharacterized protein
Search

0.40	GO:0050482	arachidonic acid secretion
0.40	GO:0048731	system development
0.40	GO:0006003	fructose 2,6-bisphosphate metabolic process
0.40	GO:0006000	fructose metabolic process
0.39	GO:0007228	positive regulation of hh target transcription factor activity
0.39	GO:0006030	chitin metabolic process
0.38	GO:0030154	cell differentiation
0.38	GO:0007186	G-protein coupled receptor signaling pathway
0.38	GO:0046835	carbohydrate phosphorylation
0.38	GO:0035120	post-embryonic appendage morphogenesis

0.43	GO:0008061	chitin binding
0.40	GO:0004623	phospholipase A2 activity
0.40	GO:0030248	cellulose binding
0.40	GO:0003873	6-phosphofructo-2-kinase activity
0.39	GO:0005119	smoothened binding
0.38	GO:0004930	G-protein coupled receptor activity
0.38	GO:0004252	serine-type endopeptidase activity
0.37	GO:0019901	protein kinase binding
0.37	GO:0042803	protein homodimerization activity
0.37	GO:0003777	microtubule motor activity

0.40	GO:0005576	extracellular region
0.39	GO:0035301	Hedgehog signaling complex
0.37	GO:0005929	cilium
0.37	GO:0005875	microtubule associated complex
0.37	GO:0012506	vesicle membrane
0.34	GO:0005886	plasma membrane
0.33	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.40	EC:3.1.1.4	GO:0004623
0.40	KEGG:R02732	GO:0003873

tr|T1FV32|T1FV32_HELRO
Uncharacterized protein
Search

tr|T1FV33|T1FV33_HELRO
Uncharacterized protein
Search

0.61	GO:0006508	proteolysis
0.46	GO:0019953	sexual reproduction
0.45	GO:0007190	activation of adenylate cyclase activity
0.44	GO:0048609	multicellular organismal reproductive process
0.42	GO:0009988	cell-cell recognition
0.42	GO:0009950	dorsal/ventral axis specification
0.41	GO:0002066	columnar/cuboidal epithelial cell development
0.41	GO:0048469	cell maturation
0.41	GO:0010927	cellular component assembly involved in morphogenesis
0.41	GO:0044706	multi-multicellular organism process

0.69	GO:0004252	serine-type endopeptidase activity
0.44	GO:0005537	mannose binding
0.40	GO:0005044	scavenger receptor activity
0.39	GO:0042806	fucose binding
0.38	GO:0005509	calcium ion binding
0.38	GO:0004040	amidase activity
0.37	GO:0070053	thrombospondin receptor activity
0.36	GO:0008201	heparin binding
0.36	GO:0001530	lipopolysaccharide binding
0.36	GO:0005515	protein binding

0.60	GO:0001669	acrosomal vesicle
0.40	GO:0044437	vacuolar part
0.39	GO:0044433	cytoplasmic vesicle part
0.39	GO:0005576	extracellular region
0.37	GO:0043234	protein complex
0.37	GO:0046658	anchored component of plasma membrane
0.36	GO:0019897	extrinsic component of plasma membrane
0.36	GO:0009897	external side of plasma membrane
0.35	GO:0005798	Golgi-associated vesicle
0.33	GO:0005634	nucleus

0.69

GO:0004252

tr|T1FV34|T1FV34_HELRO
Uncharacterized protein
Search

tr|T1FV35|T1FV35_HELRO
Uncharacterized protein
Search

tr|T1FV36|T1FV36_HELRO
Uncharacterized protein
Search

tr|T1FV37|T1FV37_HELRO
Uncharacterized protein
Search

0.76	Major facilitator superfamily transporter domain-containing protein 1

0.54	GO:0055085	transmembrane transport
0.34	GO:0006260	DNA replication
0.33	GO:0008643	carbohydrate transport

0.33	GO:0003677	DNA binding
0.33	GO:0005215	transporter activity
0.32	GO:0004386	helicase activity
0.31	GO:0030554	adenyl nucleotide binding
0.31	GO:0097367	carbohydrate derivative binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0016020

membrane

tr|T1FV38|T1FV38_HELRO
Uncharacterized protein
Search

tr|T1FV39|T1FV39_HELRO
Uncharacterized protein
Search

0.63	GO:0006468	protein phosphorylation
0.59	GO:0007165	signal transduction
0.55	GO:0071549	cellular response to dexamethasone stimulus
0.54	GO:0046627	negative regulation of insulin receptor signaling pathway
0.54	GO:0001662	behavioral fear response
0.54	GO:0045948	positive regulation of translational initiation
0.53	GO:0032869	cellular response to insulin stimulus
0.53	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway
0.52	GO:0000082	G1/S transition of mitotic cell cycle
0.52	GO:0045931	positive regulation of mitotic cell cycle

0.70	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.52	GO:0004712	protein serine/threonine/tyrosine kinase activity
0.50	GO:0004435	phosphatidylinositol phospholipase C activity
0.37	GO:0051721	protein phosphatase 2A binding
0.37	GO:0030165	PDZ domain binding
0.36	GO:0042277	peptide binding

0.47	GO:0005654	nucleoplasm
0.43	GO:0005739	mitochondrion
0.38	GO:0045202	synapse
0.38	GO:0097458	neuron part
0.38	GO:0031968	organelle outer membrane
0.37	GO:0030054	cell junction
0.37	GO:0120025	plasma membrane bounded cell projection
0.36	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0009986	cell surface
0.35	GO:0005829	cytosol

0.70	EC:2.7.11	GO:0004674
0.50	KEGG:R03435	GO:0004435

tr|T1FV40|T1FV40_HELRO
Uncharacterized protein
Search

SMYD5

0.95	SET and MYND domain-containing protein 5

0.65	GO:0060215	primitive hemopoiesis
0.64	GO:0060216	definitive hemopoiesis
0.63	GO:0045638	negative regulation of myeloid cell differentiation
0.51	GO:0032259	methylation
0.45	GO:0048738	cardiac muscle tissue development
0.45	GO:0007519	skeletal muscle tissue development
0.38	GO:0016570	histone modification
0.38	GO:0018205	peptidyl-lysine modification
0.38	GO:0008213	protein alkylation
0.38	GO:1903506	regulation of nucleic acid-templated transcription

0.52	GO:0008168	methyltransferase activity
0.43	GO:0016757	transferase activity, transferring glycosyl groups
0.40	GO:0043565	sequence-specific DNA binding
0.40	GO:0046872	metal ion binding

0.41	GO:0005634	nucleus
0.38	GO:0000785	chromatin
0.37	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

0.52

GO:0008168

tr|T1FV41|T1FV41_HELRO
Uncharacterized protein
Search

0.75	GO:0009190	cyclic nucleotide biosynthetic process
0.68	GO:0046058	cAMP metabolic process
0.63	GO:0035556	intracellular signal transduction
0.59	GO:0009152	purine ribonucleotide biosynthetic process
0.50	GO:0007613	memory
0.49	GO:0007409	axonogenesis
0.48	GO:0042752	regulation of circadian rhythm
0.47	GO:0046068	cGMP metabolic process
0.41	GO:0090328	regulation of olfactory learning
0.41	GO:0001661	conditioned taste aversion

0.75	GO:0016849	phosphorus-oxygen lyase activity
0.68	GO:0009975	cyclase activity
0.52	GO:1901265	nucleoside phosphate binding
0.51	GO:0036094	small molecule binding
0.43	GO:0097367	carbohydrate derivative binding
0.43	GO:0008144	drug binding
0.43	GO:0043168	anion binding
0.37	GO:0005516	calmodulin binding
0.35	GO:0004672	protein kinase activity
0.34	GO:0016775	phosphotransferase activity, nitrogenous group as acceptor

0.50	GO:0005886	plasma membrane
0.48	GO:0008074	guanylate cyclase complex, soluble
0.37	GO:0098857	membrane microdomain
0.35	GO:0070062	extracellular exosome
0.34	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.75

EC:4.6

GO:0016849

tr|T1FV42|T1FV42_HELRO
Uncharacterized protein
Search

tr|T1FV43|T1FV43_HELRO
Uncharacterized protein
Search

0.30	Phosphoribosylglycinamide synthetase

0.71	GO:0009113	purine nucleobase biosynthetic process
0.71	GO:0006189	'de novo' IMP biosynthetic process
0.43	GO:0043473	pigmentation
0.42	GO:0043010	camera-type eye development
0.42	GO:0043009	chordate embryonic development
0.39	GO:0003360	brainstem development
0.38	GO:0021549	cerebellum development
0.38	GO:0021987	cerebral cortex development
0.36	GO:0046654	tetrahydrofolate biosynthetic process
0.36	GO:0006544	glycine metabolic process

0.79	GO:0004641	phosphoribosylformylglycinamidine cyclo-ligase activity
0.75	GO:0004637	phosphoribosylamine-glycine ligase activity
0.69	GO:0004644	phosphoribosylglycinamide formyltransferase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0046872	metal ion binding
0.33	GO:0004643	phosphoribosylaminoimidazolecarboxamide formyltransferase activity
0.33	GO:0003937	IMP cyclohydrolase activity

0.49	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.79	EC:6.3.3.1	GO:0004641
0.79	KEGG:R04208	GO:0004641

tr|T1FV44|T1FV44_HELRO
Uncharacterized protein
Search

0.69	GO:0010951	negative regulation of endopeptidase activity
0.39	GO:0035556	intracellular signal transduction

0.71	GO:0004867	serine-type endopeptidase inhibitor activity
0.42	GO:0008270	zinc ion binding
0.38	GO:0003676	nucleic acid binding

0.72	GO:0005578	proteinaceous extracellular matrix
0.42	GO:0005634	nucleus

tr|T1FV45|T1FV45_HELRO
Uncharacterized protein
Search

NR2F1

0.86	Ovalbumin upstream promoter-transcription factor I

0.80	GO:0030522	intracellular receptor signaling pathway
0.79	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.46	GO:1902679	negative regulation of RNA biosynthetic process
0.45	GO:0050673	epithelial cell proliferation
0.44	GO:0048731	system development
0.41	GO:0030154	cell differentiation

0.82	GO:0004879	nuclear receptor activity
0.80	GO:0003707	steroid hormone receptor activity
0.63	GO:0043565	sequence-specific DNA binding
0.61	GO:0008270	zinc ion binding
0.50	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.46	GO:0001012	RNA polymerase II regulatory region DNA binding
0.44	GO:0003690	double-stranded DNA binding
0.37	GO:0042803	protein homodimerization activity
0.37	GO:0046982	protein heterodimerization activity
0.34	GO:0003713	transcription coactivator activity

0.61	GO:0005634	nucleus
0.43	GO:0005829	cytosol
0.43	GO:0070013	intracellular organelle lumen
0.39	GO:0044446	intracellular organelle part

tr|T1FV46|T1FV46_HELRO
40S ribosomal protein S8
Search

RPS8

0.66	40S ribosomal protein S8

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.42	GO:0042274	ribosomal small subunit biogenesis
0.40	GO:0016072	rRNA metabolic process
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0043009	chordate embryonic development
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.33	GO:0019083	viral transcription

0.64	GO:0003735	structural constituent of ribosome
0.33	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.61	GO:0005840	ribosome
0.44	GO:0044445	cytosolic part
0.41	GO:0005783	endoplasmic reticulum
0.39	GO:0044446	intracellular organelle part
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.34	GO:0005634	nucleus
0.33	GO:0043233	organelle lumen
0.30	GO:0031224	intrinsic component of membrane

tr|T1FV47|T1FV47_HELRO
AP complex subunit beta
Search

AP1B1

0.64	AP complex subunit beta

0.69	GO:0006886	intracellular protein transport
0.69	GO:0016192	vesicle-mediated transport
0.46	GO:0048513	animal organ development
0.44	GO:0007368	determination of left/right symmetry
0.42	GO:0072359	circulatory system development
0.38	GO:0048882	lateral line development
0.38	GO:0050974	detection of mechanical stimulus involved in sensory perception
0.38	GO:2000649	regulation of sodium ion transmembrane transporter activity
0.38	GO:0035315	hair cell differentiation
0.38	GO:1903076	regulation of protein localization to plasma membrane

0.80	GO:0030276	clathrin binding
0.43	GO:0019901	protein kinase binding
0.34	GO:0004725	protein tyrosine phosphatase activity
0.33	GO:0008565	protein transporter activity
0.32	GO:0046872	metal ion binding

0.79	GO:0030131	clathrin adaptor complex
0.45	GO:0005794	Golgi apparatus
0.43	GO:0030136	clathrin-coated vesicle
0.42	GO:0005905	clathrin-coated pit
0.40	GO:0005829	cytosol
0.40	GO:0031984	organelle subcompartment
0.36	GO:0030662	coated vesicle membrane
0.36	GO:0005886	plasma membrane
0.34	GO:0005765	lysosomal membrane
0.34	GO:0030666	endocytic vesicle membrane

0.34

GO:0004725

tr|T1FV48|T1FV48_HELRO
Uncharacterized protein
Search

tr|T1FV49|T1FV49_HELRO
Uncharacterized protein
Search

tr|T1FV50|T1FV50_HELRO
Uncharacterized protein
Search

tr|T1FV51|T1FV51_HELRO
Uncharacterized protein
Search

0.44	GO:0035023	regulation of Rho protein signal transduction
0.41	GO:0016192	vesicle-mediated transport
0.41	GO:0046907	intracellular transport
0.41	GO:0016441	posttranscriptional gene silencing
0.41	GO:0010390	histone monoubiquitination
0.40	GO:0065009	regulation of molecular function
0.40	GO:0015031	protein transport
0.40	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic
0.39	GO:0006401	RNA catabolic process
0.39	GO:0007165	signal transduction

0.44	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.42	GO:0046982	protein heterodimerization activity
0.41	GO:0000175	3'-5'-exoribonuclease activity
0.40	GO:0003700	DNA binding transcription factor activity
0.39	GO:0004842	ubiquitin-protein transferase activity
0.39	GO:0046872	metal ion binding
0.38	GO:0003924	GTPase activity
0.38	GO:0003677	DNA binding
0.37	GO:0032550	purine ribonucleoside binding
0.37	GO:0019001	guanyl nucleotide binding

0.44	GO:0005634	nucleus
0.41	GO:0030906	retromer, cargo-selective complex
0.41	GO:0000932	P-body
0.40	GO:0000178	exosome (RNase complex)
0.39	GO:0030117	membrane coat
0.38	GO:0005829	cytosol
0.38	GO:0043233	organelle lumen
0.36	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

0.41	EC:3.1.13	GO:0000175
0.39	KEGG:R03876	GO:0004842

tr|T1FV52|T1FV52_HELRO
Uncharacterized protein
Search

0.65	GO:0000904	cell morphogenesis involved in differentiation
0.60	GO:0007634	optokinetic behavior
0.60	GO:0031581	hemidesmosome assembly
0.60	GO:0048570	notochord morphogenesis
0.60	GO:0022617	extracellular matrix disassembly
0.59	GO:0050908	detection of light stimulus involved in visual perception
0.58	GO:0048854	brain morphogenesis
0.58	GO:0006928	movement of cell or subcellular component
0.57	GO:0031589	cell-substrate adhesion
0.57	GO:0061053	somite development

0.56

GO:0005201

extracellular matrix structural constituent

0.59	GO:0005604	basement membrane
0.30	GO:0016020	membrane

tr|T1FV53|T1FV53_HELRO
Uncharacterized protein
Search

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.46	GO:0030518	intracellular steroid hormone receptor signaling pathway
0.45	GO:0019827	stem cell population maintenance
0.41	GO:0006367	transcription initiation from RNA polymerase II promoter
0.41	GO:0021591	ventricular system development
0.40	GO:0048514	blood vessel morphogenesis
0.39	GO:0045893	positive regulation of transcription, DNA-templated

0.79	GO:0001104	RNA polymerase II transcription cofactor activity
0.41	GO:0003713	transcription coactivator activity
0.38	GO:0004872	receptor activity
0.35	GO:0042809	vitamin D receptor binding

0.77	GO:0016592	mediator complex
0.44	GO:0070847	core mediator complex
0.30	GO:0016021	integral component of membrane

tr|T1FV54|T1FV54_HELRO
Uncharacterized protein
Search

0.72	Myocyte enhancer factor 2 b

0.74	GO:0045944	positive regulation of transcription by RNA polymerase II
0.58	GO:0006351	transcription, DNA-templated
0.41	GO:0060914	heart formation
0.41	GO:0051146	striated muscle cell differentiation
0.40	GO:0035051	cardiocyte differentiation
0.40	GO:0014706	striated muscle tissue development
0.40	GO:0055001	muscle cell development
0.39	GO:0003143	embryonic heart tube morphogenesis
0.37	GO:0046928	regulation of neurotransmitter secretion
0.37	GO:0000122	negative regulation of transcription by RNA polymerase II

0.76	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.68	GO:0046983	protein dimerization activity
0.36	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.35	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding
0.35	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding
0.35	GO:0003680	AT DNA binding
0.35	GO:0001158	enhancer sequence-specific DNA binding
0.35	GO:0033613	activating transcription factor binding
0.34	GO:0071837	HMG box domain binding
0.34	GO:0042826	histone deacetylase binding

0.61	GO:0005634	nucleus
0.33	GO:0070013	intracellular organelle lumen
0.33	GO:0098794	postsynapse
0.33	GO:0043234	protein complex
0.33	GO:0044446	intracellular organelle part
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.34

GO:0032440

tr|T1FV55|T1FV55_HELRO
Uncharacterized protein
Search

tr|T1FV56|T1FV56_HELRO
Uncharacterized protein
Search

tr|T1FV57|T1FV57_HELRO
Uncharacterized protein
Search

0.65	GO:0016567	protein ubiquitination
0.58	GO:0006996	organelle organization
0.38	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.37	GO:0090419	negative regulation of transcription involved in G2/M transition of mitotic cell cycle
0.37	GO:1903468	positive regulation of DNA replication initiation
0.37	GO:0090282	positive regulation of transcription involved in G2/M transition of mitotic cell cycle
0.37	GO:2000221	negative regulation of pseudohyphal growth
0.37	GO:0071930	negative regulation of transcription involved in G1/S transition of mitotic cell cycle
0.37	GO:0061186	negative regulation of chromatin silencing at silent mating-type cassette
0.36	GO:0042981	regulation of apoptotic process

0.65	GO:0004842	ubiquitin-protein transferase activity
0.48	GO:0016874	ligase activity
0.38	GO:0005164	tumor necrosis factor receptor binding
0.36	GO:0001085	RNA polymerase II transcription factor binding
0.36	GO:0003688	DNA replication origin binding
0.36	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.35	GO:0003682	chromatin binding
0.35	GO:0003777	microtubule motor activity
0.35	GO:0008017	microtubule binding
0.35	GO:0008270	zinc ion binding

0.34	GO:0005829	cytosol
0.34	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.48	EC:6	GO:0016874
0.65	KEGG:R03876	GO:0004842

tr|T1FV58|T1FV58_HELRO
Uncharacterized protein
Search

0.10	Leucine-rich repeat flightless-interacting protein 2-like protein

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.35	GO:1902679	negative regulation of RNA biosynthetic process
0.35	GO:0009950	dorsal/ventral axis specification
0.34	GO:0044093	positive regulation of molecular function
0.34	GO:0016055	Wnt signaling pathway
0.34	GO:0048518	positive regulation of biological process
0.32	GO:0006351	transcription, DNA-templated
0.32	GO:0006030	chitin metabolic process

0.39	GO:0030275	LRR domain binding
0.37	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.37	GO:0045296	cadherin binding
0.37	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.36	GO:0042803	protein homodimerization activity
0.32	GO:0051087	chaperone binding
0.32	GO:0008061	chitin binding
0.32	GO:0003755	peptidyl-prolyl cis-trans isomerase activity

0.35	GO:0005829	cytosol
0.34	GO:0005886	plasma membrane
0.33	GO:0005581	collagen trimer
0.32	GO:0005634	nucleus
0.32	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.32

GO:0003755

tr|T1FV59|T1FV59_HELRO
Uncharacterized protein
Search

tr|T1FV60|T1FV60_HELRO
Uncharacterized protein
Search

0.61	GO:0006508	proteolysis
0.53	GO:0030574	collagen catabolic process

0.70	GO:0004222	metalloendopeptidase activity
0.63	GO:0008270	zinc ion binding
0.35	GO:0004386	helicase activity

0.74	GO:0031012	extracellular matrix
0.30	GO:0031224	intrinsic component of membrane

0.70

GO:0004222

tr|T1FV61|T1FV61_HELRO
Uncharacterized protein
Search

0.61	GO:0006508	proteolysis
0.51	GO:0030574	collagen catabolic process
0.38	GO:0042756	drinking behavior
0.37	GO:0001822	kidney development
0.36	GO:0006468	protein phosphorylation

0.70	GO:0004222	metalloendopeptidase activity
0.63	GO:0008270	zinc ion binding
0.36	GO:0004672	protein kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.74	GO:0031012	extracellular matrix
0.30	GO:0031224	intrinsic component of membrane

0.70

GO:0004222

tr|T1FV62|T1FV62_HELRO
Uncharacterized protein
Search

PLEKHB2

0.82	Pleckstrin like proteiny domain-containing family B member 2

0.55

GO:0045595

regulation of cell differentiation

0.44	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.35	GO:0005515	protein binding

0.46	GO:0055038	recycling endosome membrane
0.30	GO:0044425	membrane part

tr|T1FV63|T1FV63_HELRO
Uncharacterized protein
Search

tr|T1FV64|T1FV64_HELRO
Uncharacterized protein
Search

0.87

GO:0090084

negative regulation of inclusion body assembly

0.85	GO:0030544	Hsp70 protein binding
0.84	GO:0070628	proteasome binding
0.77	GO:0051087	chaperone binding

0.61	GO:0005634	nucleus
0.61	GO:0005739	mitochondrion

tr|T1FV65|T1FV65_HELRO
MICOS complex subunit MIC60
Search

0.42	MICOS complex subunit MIC60

0.52	GO:0042407	cristae formation
0.50	GO:0051560	mitochondrial calcium ion homeostasis
0.43	GO:0070584	mitochondrion morphogenesis
0.40	GO:0000302	response to reactive oxygen species
0.34	GO:0009409	response to cold

0.33	GO:0005515	protein binding
0.33	GO:0003723	RNA binding

0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.48	GO:0098798	mitochondrial protein complex
0.48	GO:0043209	myelin sheath
0.46	GO:0031301	integral component of organelle membrane
0.43	GO:0098796	membrane protein complex

tr|T1FV66|T1FV66_HELRO
Uncharacterized protein
Search

PCSK1

0.84	Proprotein convertase subtilisin/kexin type

0.61	GO:0006508	proteolysis
0.49	GO:0042445	hormone metabolic process
0.48	GO:0051604	protein maturation
0.43	GO:0006518	peptide metabolic process
0.42	GO:0043604	amide biosynthetic process
0.41	GO:1905910	negative regulation of dauer entry
0.40	GO:0045887	positive regulation of synaptic growth at neuromuscular junction
0.40	GO:0070593	dendrite self-avoidance
0.40	GO:1901142	insulin metabolic process
0.40	GO:2000009	negative regulation of protein localization to cell surface

0.69	GO:0004252	serine-type endopeptidase activity
0.47	GO:0042802	identical protein binding
0.37	GO:0005102	receptor binding
0.35	GO:0043559	insulin binding
0.34	GO:0051087	chaperone binding
0.34	GO:0032403	protein complex binding
0.33	GO:0046872	metal ion binding

0.48	GO:0005615	extracellular space
0.39	GO:0043025	neuronal cell body
0.38	GO:0030133	transport vesicle
0.38	GO:0034774	secretory granule lumen
0.35	GO:0043005	neuron projection
0.35	GO:0005802	trans-Golgi network
0.35	GO:0005783	endoplasmic reticulum
0.34	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0098793	presynapse
0.34	GO:0120038	plasma membrane bounded cell projection part

0.69

GO:0004252

tr|T1FV67|T1FV67_HELRO
Uncharacterized protein
Search

0.61	GO:0006508	proteolysis
0.36	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.35	GO:0006396	RNA processing

0.70	GO:0004222	metalloendopeptidase activity
0.54	GO:0046872	metal ion binding
0.37	GO:0004525	ribonuclease III activity
0.35	GO:0004180	carboxypeptidase activity

0.30

GO:0031224

intrinsic component of membrane

0.70

GO:0004222

tr|T1FV68|T1FV68_HELRO
Uncharacterized protein
Search

0.42	GO:0044419	interspecies interaction between organisms
0.36	GO:0048268	clathrin coat assembly
0.36	GO:0000272	polysaccharide catabolic process
0.35	GO:0051049	regulation of transport
0.35	GO:0002027	regulation of heart rate
0.35	GO:0006508	proteolysis
0.35	GO:0031321	ascospore-type prospore assembly
0.34	GO:0016310	phosphorylation
0.34	GO:0090501	RNA phosphodiester bond hydrolysis
0.34	GO:0006357	regulation of transcription by RNA polymerase II

0.57	GO:0008270	zinc ion binding
0.37	GO:0005545	1-phosphatidylinositol binding
0.36	GO:0030276	clathrin binding
0.36	GO:0070001	aspartic-type peptidase activity
0.35	GO:0004175	endopeptidase activity
0.35	GO:0001104	RNA polymerase II transcription cofactor activity
0.35	GO:0016301	kinase activity
0.35	GO:0030246	carbohydrate binding
0.35	GO:0030552	cAMP binding
0.34	GO:0004540	ribonuclease activity

0.43	GO:0036338	viral membrane
0.42	GO:0005622	intracellular
0.35	GO:0031982	vesicle
0.35	GO:0005576	extracellular region
0.34	GO:0000935	division septum
0.34	GO:0009277	fungal-type cell wall
0.34	GO:0019867	outer membrane
0.34	GO:0031974	membrane-enclosed lumen
0.34	GO:0055036	virion membrane
0.33	GO:0043234	protein complex

0.34

GO:0016874

tr|T1FV69|T1FV69_HELRO
Uncharacterized protein
Search

0.86

GO:0003953

NAD+ nucleosidase activity

tr|T1FV70|T1FV70_HELRO
Uncharacterized protein
Search

0.61	GO:0010714	positive regulation of collagen metabolic process
0.61	GO:0032965	regulation of collagen biosynthetic process
0.60	GO:0046850	regulation of bone remodeling
0.60	GO:0045669	positive regulation of osteoblast differentiation
0.52	GO:0010557	positive regulation of macromolecule biosynthetic process
0.38	GO:0006457	protein folding
0.36	GO:0001503	ossification
0.35	GO:0007275	multicellular organism development
0.34	GO:0006357	regulation of transcription by RNA polymerase II

0.38	GO:0051082	unfolded protein binding
0.34	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.33	GO:0008270	zinc ion binding
0.32	GO:0003676	nucleic acid binding

0.58	GO:0005791	rough endoplasmic reticulum
0.40	GO:0016272	prefoldin complex
0.35	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0098588	bounding membrane of organelle
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

tr|T1FV71|T1FV71_HELRO
Uncharacterized protein
Search

tr|T1FV72|T1FV72_HELRO
Uncharacterized protein
Search

tr|T1FV73|T1FV73_HELRO
Uncharacterized protein
Search

tr|T1FV74|T1FV74_HELRO
Uncharacterized protein
Search

tr|T1FV75|T1FV75_HELRO
Uncharacterized protein
Search

tr|T1FV76|T1FV76_HELRO
Uncharacterized protein
Search

0.52	Adenosine kinase b

0.77	GO:0006166	purine ribonucleoside salvage
0.75	GO:0006167	AMP biosynthetic process
0.50	GO:0016310	phosphorylation
0.47	GO:0046086	adenosine biosynthetic process
0.40	GO:0044262	cellular carbohydrate metabolic process
0.34	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
0.33	GO:0006144	purine nucleobase metabolic process
0.32	GO:0036211	protein modification process
0.32	GO:0044267	cellular protein metabolic process

0.85	GO:0004001	adenosine kinase activity
0.42	GO:0019200	carbohydrate kinase activity
0.34	GO:0004675	transmembrane receptor protein serine/threonine kinase activity
0.34	GO:0004702	signal transducer, downstream of receptor, with serine/threonine kinase activity
0.34	GO:0008270	zinc ion binding
0.33	GO:0003723	RNA binding
0.33	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.40	GO:0005829	cytosol
0.38	GO:0005634	nucleus
0.34	GO:0031514	motile cilium
0.30	GO:0016020	membrane

0.85

EC:2.7.1.20

GO:0004001

tr|T1FV77|T1FV77_HELRO
Uncharacterized protein
Search

0.58	GO:0045454	cell redox homeostasis
0.43	GO:0009408	response to heat
0.43	GO:0006457	protein folding
0.40	GO:0030433	ubiquitin-dependent ERAD pathway
0.40	GO:0006260	DNA replication
0.39	GO:0002377	immunoglobulin production
0.39	GO:0030183	B cell differentiation
0.36	GO:0000742	karyogamy involved in conjugation with cellular fusion

0.46	GO:0031072	heat shock protein binding
0.43	GO:0051082	unfolded protein binding
0.40	GO:0051787	misfolded protein binding
0.39	GO:0008270	zinc ion binding
0.38	GO:0051087	chaperone binding
0.37	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005509	calcium ion binding
0.33	GO:0003723	RNA binding

0.39	GO:0005788	endoplasmic reticulum lumen
0.36	GO:0005829	cytosol
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.30	GO:0031224	intrinsic component of membrane

tr|T1FV78|T1FV78_HELRO
Uncharacterized protein
Search

CEP41

0.93	Centrosomal protein of 41 kDa B

0.80	GO:0060271	cilium assembly
0.64	GO:0018095	protein polyglutamylation
0.50	GO:0001578	microtubule bundle formation
0.48	GO:0015031	protein transport
0.40	GO:0000086	G2/M transition of mitotic cell cycle
0.39	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.39	GO:0140056	organelle localization by membrane tethering

0.54	GO:0070740	tubulin-glutamic acid ligase activity
0.36	GO:0005515	protein binding

0.80	GO:0036064	ciliary basal body
0.80	GO:0005814	centriole
0.73	GO:0005813	centrosome
0.37	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.54

EC:6.3.2

GO:0070740

tr|T1FV79|T1FV79_HELRO
Uncharacterized protein
Search

0.52	GO:0045944	positive regulation of transcription by RNA polymerase II
0.52	GO:0001933	negative regulation of protein phosphorylation
0.39	GO:0031156	regulation of sorocarp development
0.39	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA
0.38	GO:0034729	histone H3-K79 methylation
0.37	GO:0043085	positive regulation of catalytic activity
0.37	GO:0051726	regulation of cell cycle
0.35	GO:0006281	DNA repair
0.34	GO:0006351	transcription, DNA-templated

0.39	GO:0031151	histone methyltransferase activity (H3-K79 specific)
0.38	GO:0008047	enzyme activator activity
0.35	GO:0003723	RNA binding

0.50	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1FV80|T1FV80_HELRO
Uncharacterized protein
Search

0.59	GO:0006508	proteolysis
0.41	GO:0051493	regulation of cytoskeleton organization
0.40	GO:0007586	digestion
0.37	GO:0021785	branchiomotor neuron axon guidance
0.36	GO:0006869	lipid transport
0.36	GO:0007420	brain development
0.34	GO:0051260	protein homooligomerization
0.34	GO:0048523	negative regulation of cellular process
0.34	GO:0042981	regulation of apoptotic process
0.34	GO:0006413	translational initiation

0.80	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.57	GO:0005509	calcium ion binding
0.37	GO:0005319	lipid transporter activity
0.34	GO:0003743	translation initiation factor activity
0.34	GO:0017111	nucleoside-triphosphatase activity
0.34	GO:0004866	endopeptidase inhibitor activity
0.33	GO:0004519	endonuclease activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0032561	guanyl ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.44	GO:0005622	intracellular
0.44	GO:0009986	cell surface
0.35	GO:0005615	extracellular space
0.34	GO:0005925	focal adhesion
0.34	GO:1903561	extracellular vesicle
0.30	GO:0016020	membrane

0.34

EC:3.6.1.15

GO:0017111

tr|T1FV81|T1FV81_HELRO
Uncharacterized protein
Search

0.43	GO:0035950	regulation of oligopeptide transport by regulation of transcription from RNA polymerase II promoter
0.43	GO:2000877	negative regulation of oligopeptide transport
0.43	GO:2000531	regulation of fatty acid biosynthetic process by regulation of transcription from RNA polymerase II promoter
0.43	GO:0090089	regulation of dipeptide transport
0.42	GO:0016584	nucleosome positioning
0.40	GO:2001020	regulation of response to DNA damage stimulus
0.40	GO:0000122	negative regulation of transcription by RNA polymerase II
0.40	GO:0006338	chromatin remodeling
0.40	GO:0043547	positive regulation of GTPase activity
0.39	GO:0006366	transcription by RNA polymerase II

0.45	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity
0.42	GO:0033925	mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity
0.42	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.41	GO:0046982	protein heterodimerization activity
0.41	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.41	GO:0042826	histone deacetylase binding
0.40	GO:0005096	GTPase activator activity
0.38	GO:0016746	transferase activity, transferring acyl groups
0.36	GO:0003676	nucleic acid binding
0.35	GO:0046872	metal ion binding

0.51	GO:0005576	extracellular region
0.41	GO:0017053	transcriptional repressor complex
0.40	GO:0005634	nucleus
0.38	GO:0044462	external encapsulating structure part
0.38	GO:0019867	outer membrane
0.38	GO:0030313	cell envelope
0.30	GO:0016021	integral component of membrane

0.45

EC:3.5.1.28

GO:0008745

tr|T1FV82|T1FV82_HELRO
Uncharacterized protein
Search

tr|T1FV83|T1FV83_HELRO
Uncharacterized protein
Search

0.43	GO:0072502	cellular trivalent inorganic anion homeostasis
0.43	GO:0072501	cellular divalent inorganic anion homeostasis
0.43	GO:0030320	cellular monovalent inorganic anion homeostasis
0.43	GO:0055062	phosphate ion homeostasis
0.43	GO:0035435	phosphate ion transmembrane transport
0.42	GO:0009615	response to virus
0.40	GO:0051828	entry into other organism involved in symbiotic interaction
0.39	GO:0019058	viral life cycle
0.38	GO:0014004	microglia differentiation
0.36	GO:0001501	skeletal system development

0.45	GO:0000822	inositol hexakisphosphate binding
0.45	GO:0104005	hijacked molecular function
0.43	GO:0015114	phosphate ion transmembrane transporter activity
0.42	GO:0015562	efflux transmembrane transporter activity
0.39	GO:0004872	receptor activity
0.34	GO:0004335	galactokinase activity
0.34	GO:0005534	galactose binding
0.33	GO:0003779	actin binding
0.32	GO:0004871	signal transducer activity
0.32	GO:0003723	RNA binding

0.39	GO:0031226	intrinsic component of plasma membrane
0.34	GO:0005737	cytoplasm
0.32	GO:0005634	nucleus
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016021	integral component of membrane

0.34	EC:2.7.1.6	GO:0004335
0.34	KEGG:R01092	GO:0004335

tr|T1FV84|T1FV84_HELRO
Uncharacterized protein
Search

tr|T1FV85|T1FV85_HELRO
Uncharacterized protein
Search

tr|T1FV86|T1FV86_HELRO
Uncharacterized protein
Search

0.44	GO:0007093	mitotic cell cycle checkpoint
0.44	GO:0051304	chromosome separation
0.42	GO:0042254	ribosome biogenesis
0.41	GO:0036211	protein modification process
0.41	GO:2001141	regulation of RNA biosynthetic process
0.41	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.41	GO:0010468	regulation of gene expression
0.40	GO:0044267	cellular protein metabolic process
0.39	GO:0016310	phosphorylation
0.38	GO:0006996	organelle organization

0.44	GO:0004712	protein serine/threonine/tyrosine kinase activity
0.41	GO:0003700	DNA binding transcription factor activity
0.40	GO:0003723	RNA binding
0.40	GO:0046872	metal ion binding
0.40	GO:0017076	purine nucleotide binding
0.40	GO:0097367	carbohydrate derivative binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0008144	drug binding
0.37	GO:0022839	ion gated channel activity
0.37	GO:0008381	mechanosensitive ion channel activity

0.44	GO:0005634	nucleus
0.39	GO:0043232	intracellular non-membrane-bounded organelle
0.39	GO:0070013	intracellular organelle lumen
0.38	GO:0044446	intracellular organelle part
0.37	GO:0034703	cation channel complex
0.37	GO:0099512	supramolecular fiber
0.36	GO:0043234	protein complex
0.35	GO:0005887	integral component of plasma membrane
0.35	GO:0030686	90S preribosome
0.35	GO:0005934	cellular bud tip

0.44	EC:2.7.12.1	GO:0004712
0.36	KEGG:R03876	GO:0004842

tr|T1FV87|T1FV87_HELRO
Uncharacterized protein
Search

tr|T1FV88|T1FV88_HELRO
Uncharacterized protein
Search

0.11	small acidic protein-like

0.58	GO:0006629	lipid metabolic process
0.40	GO:0032259	methylation
0.40	GO:0015031	protein transport

0.48	GO:0016787	hydrolase activity
0.44	GO:0008017	microtubule binding
0.40	GO:0008168	methyltransferase activity

0.40	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.48

GO:0016787

tr|T1FV89|T1FV89_HELRO
Uncharacterized protein
Search

0.67	GO:0071805	potassium ion transmembrane transport
0.44	GO:0030322	stabilization of membrane potential
0.33	GO:0006468	protein phosphorylation
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.70	GO:0005267	potassium channel activity
0.42	GO:0022842	narrow pore channel activity
0.38	GO:0022843	voltage-gated cation channel activity
0.35	GO:0005509	calcium ion binding
0.33	GO:0004672	protein kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.38	GO:0005887	integral component of plasma membrane
0.32	GO:0005634	nucleus

tr|T1FV90|T1FV90_HELRO
Alpha-1,3-glucosyltransferase
Search

0.42	Alpha-1,3-glucosyltransferase

0.73	GO:0006486	protein glycosylation
0.52	GO:0006490	oligosaccharide-lipid intermediate biosynthetic process
0.46	GO:0097502	mannosylation
0.34	GO:0007377	germ-band extension
0.34	GO:0003384	apical constriction involved in gastrulation
0.32	GO:0006508	proteolysis

0.69	GO:0016758	transferase activity, transferring hexosyl groups
0.32	GO:0005515	protein binding
0.32	GO:0004222	metalloendopeptidase activity
0.32	GO:0008270	zinc ion binding

0.72	GO:0005789	endoplasmic reticulum membrane
0.32	GO:0031012	extracellular matrix
0.30	GO:0016021	integral component of membrane

0.69

GO:0016758

tr|T1FV91|T1FV91_HELRO
Uncharacterized protein
Search

0.10	High affinity cationic amino acid transporter 1

0.55	GO:0055085	transmembrane transport
0.46	GO:0015807	L-amino acid transport

0.57

GO:0022857

transmembrane transporter activity

0.30

GO:0016021

integral component of membrane

tr|T1FV92|T1FV92_HELRO
Uncharacterized protein
Search

0.60	GO:0005975	carbohydrate metabolic process
0.45	GO:1990966	ATP generation from poly-ADP-D-ribose
0.35	GO:0016045	detection of bacterium
0.34	GO:0006535	cysteine biosynthetic process from serine
0.34	GO:0036099	female germ-line stem cell population maintenance
0.34	GO:0030576	Cajal body organization
0.34	GO:0051457	maintenance of protein location in nucleus
0.34	GO:0045739	positive regulation of DNA repair
0.34	GO:0006950	response to stress
0.34	GO:0035065	regulation of histone acetylation

0.85	GO:0004649	poly(ADP-ribose) glycohydrolase activity
0.35	GO:0004683	calmodulin-dependent protein kinase activity
0.34	GO:0005516	calmodulin binding
0.33	GO:0003682	chromatin binding
0.32	GO:0004519	endonuclease activity
0.32	GO:0003723	RNA binding
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0046872	metal ion binding
0.32	GO:0032561	guanyl ribonucleotide binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.40	GO:0005654	nucleoplasm
0.39	GO:0005829	cytosol
0.33	GO:0005759	mitochondrial matrix
0.33	GO:0000785	chromatin
0.32	GO:0005681	spliceosomal complex
0.30	GO:0031224	intrinsic component of membrane

0.85

EC:3.2.1.143

GO:0004649

tr|T1FV93|T1FV93_HELRO
Uncharacterized protein
Search

0.56	Thousand and one amino acid protein kinase

0.63	GO:0006468	protein phosphorylation
0.46	GO:1902533	positive regulation of intracellular signal transduction
0.45	GO:0048036	central complex development
0.44	GO:0036335	intestinal stem cell homeostasis
0.44	GO:0035330	regulation of hippo signaling
0.44	GO:0042220	response to cocaine
0.44	GO:0016319	mushroom body development
0.44	GO:0035094	response to nicotine
0.44	GO:0046621	negative regulation of organ growth
0.43	GO:0006915	apoptotic process

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0005057	signal transducer activity, downstream of receptor
0.33	GO:0005515	protein binding

0.43	GO:0045178	basal part of cell
0.41	GO:0005819	spindle
0.40	GO:0005874	microtubule
0.36	GO:0005886	plasma membrane
0.34	GO:0043204	perikaryon
0.34	GO:0005737	cytoplasm
0.34	GO:0030424	axon
0.30	GO:0016021	integral component of membrane

tr|T1FV94|T1FV94_HELRO
Uncharacterized protein
Search

tr|T1FV95|T1FV95_HELRO
Uncharacterized protein
Search

tr|T1FV96|T1FV96_HELRO
Uncharacterized protein
Search

0.10	Pirin C-terminal cupin domain protein

0.83	GO:1903131	mononuclear cell differentiation
0.79	GO:0002573	myeloid leukocyte differentiation
0.54	GO:1903506	regulation of nucleic acid-templated transcription
0.52	GO:0055114	oxidation-reduction process
0.39	GO:0007586	digestion
0.38	GO:0006351	transcription, DNA-templated
0.38	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.38	GO:0010468	regulation of gene expression

0.84	GO:0008127	quercetin 2,3-dioxygenase activity
0.70	GO:0003712	transcription cofactor activity
0.51	GO:0046872	metal ion binding
0.36	GO:0005515	protein binding

0.65	GO:0005829	cytosol
0.58	GO:0005634	nucleus
0.36	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.84	EC:1.13.11.24	GO:0008127
0.84	KEGG:R02156	GO:0008127

tr|T1FV97|T1FV97_HELRO
Uncharacterized protein
Search

tr|T1FV98|T1FV98_HELRO
Uncharacterized protein
Search

tr|T1FV99|T1FV99_HELRO
Uncharacterized protein
Search

0.63	GO:0006468	protein phosphorylation
0.48	GO:0034340	response to type I interferon
0.48	GO:0035456	response to interferon-beta
0.48	GO:0010884	positive regulation of lipid storage
0.47	GO:0038061	NIK/NF-kappaB signaling
0.47	GO:0007249	I-kappaB kinase/NF-kappaB signaling
0.47	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage
0.47	GO:0098586	cellular response to virus
0.46	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.45	GO:0051260	protein homooligomerization

0.64	GO:0004672	protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0036435	K48-linked polyubiquitin modification-dependent protein binding
0.46	GO:0005057	signal transducer activity, downstream of receptor
0.45	GO:0031625	ubiquitin protein ligase binding
0.41	GO:0005509	calcium ion binding
0.36	GO:0005516	calmodulin binding

0.47	GO:0016605	PML body
0.40	GO:0031966	mitochondrial membrane
0.35	GO:0005829	cytosol
0.34	GO:0010008	endosome membrane
0.33	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.30	GO:0016021	integral component of membrane

0.32

GO:0008375

tr|T1FVA0|T1FVA0_HELRO
Uncharacterized protein
Search

tr|T1FVA1|T1FVA1_HELRO
Uncharacterized protein
Search

0.73	GO:0031047	gene silencing by RNA
0.44	GO:0006401	RNA catabolic process
0.42	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.39	GO:0006468	protein phosphorylation
0.37	GO:0043044	ATP-dependent chromatin remodeling
0.36	GO:0006357	regulation of transcription by RNA polymerase II

0.42	GO:0004518	nuclease activity
0.39	GO:0016301	kinase activity
0.39	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.38	GO:0050825	ice binding
0.38	GO:0032559	adenyl ribonucleotide binding
0.38	GO:0140096	catalytic activity, acting on a protein
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0001104	RNA polymerase II transcription cofactor activity
0.37	GO:0008270	zinc ion binding

0.78	GO:0016442	RISC complex
0.42	GO:0001669	acrosomal vesicle
0.42	GO:0005634	nucleus
0.36	GO:0031974	membrane-enclosed lumen
0.35	GO:0043234	protein complex
0.34	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.42

GO:0004518

tr|T1FVA2|T1FVA2_HELRO
Uncharacterized protein
Search

PITRM1

0.71	Pitrilysin metallopeptidase 1

0.60

GO:0006508

proteolysis

0.57	GO:0004222	metalloendopeptidase activity
0.54	GO:0046872	metal ion binding

0.60

GO:0005759

mitochondrial matrix

0.57

GO:0004222

tr|T1FVA3|T1FVA3_HELRO
Uncharacterized protein
Search

0.40	GO:0006259	DNA metabolic process
0.38	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.34	GO:0060906	negative regulation of chromatin silencing by small RNA
0.33	GO:0031125	rRNA 3'-end processing
0.33	GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.32	GO:0008643	carbohydrate transport
0.32	GO:0055085	transmembrane transport

0.54	GO:0008270	zinc ion binding
0.50	GO:0003676	nucleic acid binding
0.40	GO:0004527	exonuclease activity
0.33	GO:0032296	double-stranded RNA-specific ribonuclease activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.31	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|T1FVA4|T1FVA4_HELRO
Uncharacterized protein
Search

tr|T1FVA5|T1FVA5_HELRO
Uncharacterized protein
Search

0.71

GO:0040016

embryonic cleavage

0.39

GO:0005515

protein binding

0.67	GO:0032154	cleavage furrow
0.62	GO:0005813	centrosome
0.41	GO:0019028	viral capsid
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1FVA6|T1FVA6_HELRO
Uncharacterized protein
Search

0.40	GO:0006508	proteolysis
0.39	GO:0005975	carbohydrate metabolic process
0.37	GO:0006030	chitin metabolic process
0.36	GO:0016567	protein ubiquitination
0.34	GO:0016310	phosphorylation
0.34	GO:0060255	regulation of macromolecule metabolic process

0.49	GO:0003677	DNA binding
0.43	GO:0030248	cellulose binding
0.43	GO:0004222	metalloendopeptidase activity
0.41	GO:0008270	zinc ion binding
0.40	GO:0015925	galactosidase activity
0.38	GO:0030570	pectate lyase activity
0.37	GO:0003682	chromatin binding
0.37	GO:0015926	glucosidase activity
0.37	GO:0008061	chitin binding
0.37	GO:0004842	ubiquitin-protein transferase activity

0.47	GO:0005576	extracellular region
0.38	GO:0045095	keratin filament
0.37	GO:0009341	beta-galactosidase complex
0.30	GO:0031224	intrinsic component of membrane

0.43	EC:3.4.24	GO:0004222
0.37	KEGG:R03876	GO:0004842

tr|T1FVA7|T1FVA7_HELRO
Uncharacterized protein
Search

tr|T1FVA8|T1FVA8_HELRO
Uncharacterized protein
Search

0.51	GO:0035335	peptidyl-tyrosine dephosphorylation
0.44	GO:0016567	protein ubiquitination
0.43	GO:0006357	regulation of transcription by RNA polymerase II
0.40	GO:0035556	intracellular signal transduction

0.51	GO:0004725	protein tyrosine phosphatase activity
0.44	GO:0004842	ubiquitin-protein transferase activity
0.44	GO:0003700	DNA binding transcription factor activity
0.41	GO:0046872	metal ion binding
0.40	GO:0016874	ligase activity
0.40	GO:0003676	nucleic acid binding

0.40	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.51	EC:3.1.3.48	GO:0004725
0.44	KEGG:R03876	GO:0004842

tr|T1FVA9|T1FVA9_HELRO
Uncharacterized protein
Search

tr|T1FVB0|T1FVB0_HELRO
Uncharacterized protein
Search

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.51	GO:0060912	cardiac cell fate specification
0.50	GO:0046959	habituation
0.50	GO:0045887	positive regulation of synaptic growth at neuromuscular junction
0.45	GO:0048523	negative regulation of cellular process
0.44	GO:0008589	regulation of smoothened signaling pathway
0.43	GO:0010558	negative regulation of macromolecule biosynthetic process
0.43	GO:0051172	negative regulation of nitrogen compound metabolic process

0.60	GO:0043565	sequence-specific DNA binding
0.59	GO:0008270	zinc ion binding
0.57	GO:0003700	DNA binding transcription factor activity
0.37	GO:0005515	protein binding
0.37	GO:0031492	nucleosomal DNA binding
0.37	GO:0035326	enhancer binding
0.36	GO:0001012	RNA polymerase II regulatory region DNA binding
0.35	GO:0003690	double-stranded DNA binding

0.52	GO:0005654	nucleoplasm
0.49	GO:0090545	CHD-type complex
0.47	GO:0017053	transcriptional repressor complex
0.35	GO:0005576	extracellular region
0.34	GO:0043234	protein complex

tr|T1FVB1|T1FVB1_HELRO
Uncharacterized protein
Search

tr|T1FVB2|T1FVB2_HELRO
Uncharacterized protein
Search

0.54	GO:0048208	COPII vesicle coating
0.50	GO:0009734	auxin-activated signaling pathway
0.46	GO:0060255	regulation of macromolecule metabolic process
0.46	GO:0031326	regulation of cellular biosynthetic process
0.46	GO:0051171	regulation of nitrogen compound metabolic process
0.46	GO:0080090	regulation of primary metabolic process
0.44	GO:0006325	chromatin organization
0.43	GO:0034198	cellular response to amino acid starvation
0.43	GO:0006351	transcription, DNA-templated
0.41	GO:0090113	regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis

0.45	GO:0003712	transcription cofactor activity
0.43	GO:0005515	protein binding
0.42	GO:0003677	DNA binding
0.42	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.41	GO:0008270	zinc ion binding
0.40	GO:0003682	chromatin binding
0.40	GO:0004407	histone deacetylase activity
0.39	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.39	GO:0015616	DNA translocase activity
0.39	GO:0016853	isomerase activity

0.52	GO:0005634	nucleus
0.49	GO:0000139	Golgi membrane
0.46	GO:0070013	intracellular organelle lumen
0.43	GO:1902494	catalytic complex
0.42	GO:0000785	chromatin
0.40	GO:0070971	endoplasmic reticulum exit site
0.39	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.40

GO:0004407

tr|T1FVB3|T1FVB3_HELRO
Uncharacterized protein
Search

tr|T1FVB4|T1FVB4_HELRO
Uncharacterized protein
Search

0.53	GO:0010923	negative regulation of phosphatase activity
0.43	GO:0055085	transmembrane transport
0.42	GO:0006438	valyl-tRNA aminoacylation
0.41	GO:0106074	aminoacyl-tRNA metabolism involved in translational fidelity
0.41	GO:0007018	microtubule-based movement
0.41	GO:0045292	mRNA cis splicing, via spliceosome
0.39	GO:0051028	mRNA transport
0.38	GO:2001141	regulation of RNA biosynthetic process
0.38	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.38	GO:0010468	regulation of gene expression

0.53	GO:0019902	phosphatase binding
0.49	GO:0043492	ATPase activity, coupled to movement of substances
0.48	GO:0015405	P-P-bond-hydrolysis-driven transmembrane transporter activity
0.46	GO:0030554	adenyl nucleotide binding
0.46	GO:0097367	carbohydrate derivative binding
0.46	GO:0008144	drug binding
0.46	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0004832	valine-tRNA ligase activity
0.41	GO:0002161	aminoacyl-tRNA editing activity
0.41	GO:0003777	microtubule motor activity

0.41	GO:0005846	nuclear cap binding complex
0.41	GO:0016459	myosin complex
0.37	GO:0020020	food vacuole
0.34	GO:0030286	dynein complex
0.34	GO:0019013	viral nucleocapsid
0.34	GO:0005829	cytosol
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016020	membrane

0.42	EC:6.1.1.9	GO:0004832
0.42	KEGG:R03665	GO:0004832

tr|T1FVB5|T1FVB5_HELRO
Innexin
Search

0.37

Innexin

0.59

GO:0006811

ion transport

0.81	GO:0005921	gap junction
0.56	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1FVB6|T1FVB6_HELRO
Uncharacterized protein
Search

tr|T1FVB7|T1FVB7_HELRO
Poly [ADP-ribose] polymerase
Search

0.10	Poly [ADP-ribose] polymerase

0.82	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.35	GO:0046872	metal ion binding

0.30

GO:0044425

membrane part

0.82

EC:2.4.2.30

GO:0003950

tr|T1FVB8|T1FVB8_HELRO
Uncharacterized protein
Search

0.63	GO:0006468	protein phosphorylation
0.43	GO:0046844	micropyle formation
0.43	GO:0007561	imaginal disc eversion
0.43	GO:0007395	dorsal closure, spreading of leading edge cells
0.42	GO:0030381	chorion-containing eggshell pattern formation
0.42	GO:0034769	basement membrane disassembly
0.42	GO:0048803	imaginal disc-derived male genitalia morphogenesis
0.42	GO:0046528	imaginal disc fusion
0.42	GO:0045610	regulation of hemocyte differentiation
0.42	GO:0043652	engulfment of apoptotic cell

0.64	GO:0004672	protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0005078	MAP-kinase scaffold activity
0.40	GO:0019901	protein kinase binding
0.38	GO:0045182	translation regulator activity
0.38	GO:0004871	signal transducer activity
0.36	GO:0016775	phosphotransferase activity, nitrogenous group as acceptor

0.40	GO:0030424	axon
0.35	GO:0005622	intracellular
0.34	GO:0043227	membrane-bounded organelle
0.34	GO:0048475	coated membrane
0.34	GO:0098805	whole membrane
0.34	GO:0012505	endomembrane system
0.33	GO:0098796	membrane protein complex
0.33	GO:0044422	organelle part
0.30	GO:0016021	integral component of membrane

0.36

EC:2.7.3

GO:0016775

tr|T1FVB9|T1FVB9_HELRO
Uncharacterized protein
Search

tr|T1FVC0|T1FVC0_HELRO
Uncharacterized protein
Search

0.69	GO:0007186	G-protein coupled receptor signaling pathway
0.45	GO:0006508	proteolysis

0.70	GO:0004930	G-protein coupled receptor activity
0.52	GO:0004197	cysteine-type endopeptidase activity

0.30

GO:0044425

membrane part

0.52

EC:3.4.22

GO:0004197

tr|T1FVC1|T1FVC1_HELRO
Uncharacterized protein
Search

0.57	GO:0048268	clathrin coat assembly
0.48	GO:0009734	auxin-activated signaling pathway
0.43	GO:2001141	regulation of RNA biosynthetic process
0.43	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.43	GO:0010468	regulation of gene expression
0.42	GO:0007318	pole plasm protein localization
0.42	GO:0008103	oocyte microtubule cytoskeleton polarization
0.42	GO:0006351	transcription, DNA-templated
0.42	GO:0045451	pole plasm oskar mRNA localization
0.38	GO:0008380	RNA splicing

0.58	GO:0005545	1-phosphatidylinositol binding
0.56	GO:0030276	clathrin binding
0.42	GO:0003676	nucleic acid binding
0.40	GO:0140110	transcription regulator activity
0.40	GO:0051087	chaperone binding
0.40	GO:0031369	translation initiation factor binding
0.40	GO:0046872	metal ion binding
0.38	GO:0046983	protein dimerization activity
0.37	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.37	GO:0016301	kinase activity

0.56	GO:0030136	clathrin-coated vesicle
0.46	GO:0005634	nucleus
0.39	GO:0043234	protein complex
0.38	GO:0012505	endomembrane system
0.38	GO:0044446	intracellular organelle part
0.38	GO:0070013	intracellular organelle lumen
0.37	GO:0031248	protein acetyltransferase complex
0.37	GO:0000428	DNA-directed RNA polymerase complex
0.37	GO:1905368	peptidase complex
0.36	GO:0031975	envelope

0.37

EC:3.1.4.17

GO:0004114

tr|T1FVC2|T1FVC2_HELRO
Uncharacterized protein
Search

SETD6

0.83	SET domain containing 6

0.78	GO:0018026	peptidyl-lysine monomethylation
0.55	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.51	GO:0050727	regulation of inflammatory response
0.47	GO:0019827	stem cell population maintenance
0.47	GO:0048863	stem cell differentiation
0.47	GO:0034968	histone lysine methylation

0.72	GO:0016279	protein-lysine N-methyltransferase activity
0.55	GO:0051059	NF-kappaB binding

0.43	GO:0005829	cytosol
0.43	GO:0005634	nucleus

0.72

GO:0016279

tr|T1FVC3|T1FVC3_HELRO
Uncharacterized protein
Search

tr|T1FVC4|T1FVC4_HELRO
Uncharacterized protein
Search

tr|T1FVC5|T1FVC5_HELRO
Uncharacterized protein
Search

tr|T1FVC6|T1FVC6_HELRO
Uncharacterized protein
Search

tr|T1FVC7|T1FVC7_HELRO
Uncharacterized protein
Search

PTP4A3

0.85	Tyrosine phosphatase type IVA

0.71	GO:0006470	protein dephosphorylation
0.51	GO:0043542	endothelial cell migration
0.50	GO:1901224	positive regulation of NIK/NF-kappaB signaling
0.49	GO:0043117	positive regulation of vascular permeability
0.48	GO:1900746	regulation of vascular endothelial growth factor signaling pathway
0.48	GO:1904951	positive regulation of establishment of protein localization
0.47	GO:1990830	cellular response to leukemia inhibitory factor
0.46	GO:0007219	Notch signaling pathway
0.40	GO:1903506	regulation of nucleic acid-templated transcription
0.40	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.76	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.48	GO:0004725	protein tyrosine phosphatase activity
0.33	GO:0005515	protein binding

0.44	GO:0005634	nucleus
0.39	GO:0005737	cytoplasm
0.36	GO:0005886	plasma membrane
0.35	GO:0097708	intracellular vesicle
0.34	GO:0012505	endomembrane system
0.30	GO:0016021	integral component of membrane

0.76

GO:0008138

tr|T1FVC8|T1FVC8_HELRO
Uncharacterized protein
Search

0.10	Inositol-pentakisphosphate 2-kinase

0.56	GO:0016310	phosphorylation
0.45	GO:0006359	regulation of transcription by RNA polymerase III
0.44	GO:0006383	transcription by RNA polymerase III

0.83	GO:0035299	inositol pentakisphosphate 2-kinase activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0001026	TFIIIB-type transcription factor activity
0.37	GO:0003677	DNA binding

0.45	GO:0000126	transcription factor TFIIIB complex
0.41	GO:0005581	collagen trimer

0.83	EC:2.7.1.158	GO:0035299
0.83	KEGG:R05202	GO:0035299

tr|T1FVC9|T1FVC9_HELRO
Uncharacterized protein
Search

0.51	GO:0035335	peptidyl-tyrosine dephosphorylation
0.46	GO:0048036	central complex development
0.45	GO:0040040	thermosensory behavior
0.45	GO:1902284	neuron projection extension involved in neuron projection guidance
0.45	GO:0016319	mushroom body development
0.45	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway
0.44	GO:0048675	axon extension
0.43	GO:0007411	axon guidance
0.42	GO:0018108	peptidyl-tyrosine phosphorylation
0.41	GO:0031032	actomyosin structure organization

0.51	GO:0004725	protein tyrosine phosphatase activity
0.50	GO:0008092	cytoskeletal protein binding
0.40	GO:0005200	structural constituent of cytoskeleton
0.35	GO:0017080	sodium channel regulator activity
0.35	GO:0001784	phosphotyrosine residue binding
0.35	GO:0051117	ATPase binding

0.69	GO:0005856	cytoskeleton
0.37	GO:0005737	cytoplasm
0.34	GO:0009898	cytoplasmic side of plasma membrane
0.33	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.51

GO:0004725

tr|T1FVD0|T1FVD0_HELRO
Uncharacterized protein
Search

0.37	GO:0008612	peptidyl-lysine modification to peptidyl-hypusine
0.36	GO:0000398	mRNA splicing, via spliceosome
0.36	GO:0019358	nicotinate nucleotide salvage
0.35	GO:0006357	regulation of transcription by RNA polymerase II
0.35	GO:0009435	NAD biosynthetic process
0.34	GO:0046627	negative regulation of insulin receptor signaling pathway
0.34	GO:0042593	glucose homeostasis
0.33	GO:0055114	oxidation-reduction process
0.33	GO:0006351	transcription, DNA-templated
0.33	GO:0006886	intracellular protein transport

0.58	GO:0003723	RNA binding
0.37	GO:0019135	deoxyhypusine monooxygenase activity
0.36	GO:0004516	nicotinate phosphoribosyltransferase activity
0.35	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity
0.35	GO:0001104	RNA polymerase II transcription cofactor activity
0.34	GO:0008536	Ran GTPase binding
0.33	GO:0003682	chromatin binding
0.33	GO:0008234	cysteine-type peptidase activity

0.38	GO:0071011	precatalytic spliceosome
0.35	GO:0044451	nucleoplasm part
0.34	GO:0043234	protein complex
0.34	GO:0043232	intracellular non-membrane-bounded organelle
0.33	GO:0044444	cytoplasmic part
0.30	GO:0031224	intrinsic component of membrane

0.37	EC:1.14.99.29	GO:0019135
0.36	KEGG:R01724	GO:0004516

tr|T1FVD1|T1FVD1_HELRO
Uncharacterized protein
Search

tr|T1FVD2|T1FVD2_HELRO
Uncharacterized protein
Search

tr|T1FVD3|T1FVD3_HELRO
Uncharacterized protein
Search

tr|T1FVD4|T1FVD4_HELRO
Uncharacterized protein
Search

tr|T1FVD5|T1FVD5_HELRO
Uncharacterized protein
Search

0.48	GO:0007355	anterior region determination
0.47	GO:0007367	segment polarity determination
0.46	GO:0060255	regulation of macromolecule metabolic process
0.45	GO:0031326	regulation of cellular biosynthetic process
0.45	GO:0051171	regulation of nitrogen compound metabolic process
0.45	GO:0080090	regulation of primary metabolic process
0.45	GO:0051568	histone H3-K4 methylation
0.44	GO:0009891	positive regulation of biosynthetic process
0.44	GO:0048609	multicellular organismal reproductive process
0.44	GO:0030154	cell differentiation

0.48	GO:0046982	protein heterodimerization activity
0.46	GO:0030371	translation repressor activity
0.45	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.45	GO:0003730	mRNA 3'-UTR binding
0.44	GO:0043565	sequence-specific DNA binding
0.44	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.42	GO:0046966	thyroid hormone receptor binding
0.41	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.40	GO:0050825	ice binding
0.39	GO:0042393	histone binding

0.52	GO:0005634	nucleus
0.45	GO:0034708	methyltransferase complex
0.43	GO:0070013	intracellular organelle lumen
0.40	GO:0044446	intracellular organelle part
0.38	GO:0005667	transcription factor complex
0.36	GO:0005829	cytosol
0.36	GO:0031248	protein acetyltransferase complex
0.35	GO:0000428	DNA-directed RNA polymerase complex
0.35	GO:1905368	peptidase complex
0.35	GO:0030134	COPII-coated ER to Golgi transport vesicle

0.36

EC:2.7.1.33

GO:0004594

tr|T1FVD6|T1FVD6_HELRO
Uncharacterized protein
Search

0.46	GO:0006338	chromatin remodeling
0.43	GO:0097659	nucleic acid-templated transcription
0.42	GO:0010467	gene expression
0.42	GO:0006281	DNA repair
0.41	GO:1903506	regulation of nucleic acid-templated transcription
0.41	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.40	GO:0010468	regulation of gene expression
0.40	GO:0034645	cellular macromolecule biosynthetic process
0.38	GO:0010501	RNA secondary structure unwinding
0.38	GO:0048856	anatomical structure development

0.43	GO:0016887	ATPase activity
0.41	GO:0003700	DNA binding transcription factor activity
0.40	GO:0008270	zinc ion binding
0.40	GO:0003676	nucleic acid binding
0.38	GO:0030554	adenyl nucleotide binding
0.38	GO:0005230	extracellular ligand-gated ion channel activity
0.38	GO:0097367	carbohydrate derivative binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0008144	drug binding
0.37	GO:0003724	RNA helicase activity

0.47	GO:0031011	Ino80 complex
0.37	GO:0005730	nucleolus
0.36	GO:0005912	adherens junction
0.36	GO:0098794	postsynapse
0.34	GO:0005737	cytoplasm
0.34	GO:0005886	plasma membrane
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016021	integral component of membrane

0.43

GO:0016887

tr|T1FVD7|T1FVD7_HELRO
Uncharacterized protein
Search

GIT1

0.77	G protein-coupled receptor kinase interacting ArfGAP 1

0.74	GO:0043547	positive regulation of GTPase activity
0.60	GO:0048013	ephrin receptor signaling pathway
0.56	GO:0032465	regulation of cytokinesis
0.51	GO:0001525	angiogenesis
0.42	GO:0042074	cell migration involved in gastrulation
0.41	GO:0016310	phosphorylation
0.39	GO:0022604	regulation of cell morphogenesis
0.35	GO:0034613	cellular protein localization

0.75	GO:0005096	GTPase activator activity
0.55	GO:0032403	protein complex binding
0.52	GO:0046872	metal ion binding
0.42	GO:0016301	kinase activity

0.58	GO:0005925	focal adhesion
0.51	GO:0005829	cytosol
0.37	GO:0032587	ruffle membrane

tr|T1FVD8|T1FVD8_HELRO
Uncharacterized protein
Search

tr|T1FVD9|T1FVD9_HELRO
Uncharacterized protein
Search

tr|T1FVE0|T1FVE0_HELRO
Uncharacterized protein
Search

0.51	GO:1903506	regulation of nucleic acid-templated transcription
0.51	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.50	GO:0010468	regulation of gene expression
0.39	GO:0032482	Rab protein signal transduction
0.38	GO:0016192	vesicle-mediated transport
0.38	GO:0016573	histone acetylation
0.38	GO:0072659	protein localization to plasma membrane
0.37	GO:0017157	regulation of exocytosis
0.37	GO:0140056	organelle localization by membrane tethering
0.36	GO:0009306	protein secretion

0.43	GO:0003924	GTPase activity
0.42	GO:0032550	purine ribonucleoside binding
0.42	GO:0019001	guanyl nucleotide binding
0.38	GO:0032555	purine ribonucleotide binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0004402	histone acetyltransferase activity
0.37	GO:0046982	protein heterodimerization activity
0.35	GO:0003700	DNA binding transcription factor activity
0.34	GO:0003677	DNA binding

0.40	GO:0005634	nucleus
0.38	GO:0030667	secretory granule membrane
0.38	GO:0055037	recycling endosome
0.37	GO:0008021	synaptic vesicle
0.37	GO:0031248	protein acetyltransferase complex
0.37	GO:0005667	transcription factor complex
0.36	GO:0031974	membrane-enclosed lumen
0.35	GO:0031226	intrinsic component of plasma membrane
0.30	GO:0016021	integral component of membrane

0.38

GO:0004402

tr|T1FVE1|T1FVE1_HELRO
Uncharacterized protein
Search

0.82	GO:0061817	endoplasmic reticulum-plasma membrane tethering
0.71	GO:0006869	lipid transport
0.45	GO:0017158	regulation of calcium ion-dependent exocytosis
0.37	GO:0007340	acrosome reaction
0.36	GO:0016192	vesicle-mediated transport
0.36	GO:0098657	import into cell
0.35	GO:0006687	glycosphingolipid metabolic process
0.35	GO:0042981	regulation of apoptotic process
0.34	GO:0046907	intracellular transport
0.34	GO:0097480	establishment of synaptic vesicle localization

0.65	GO:0008289	lipid binding
0.53	GO:0050997	quaternary ammonium group binding
0.50	GO:0070405	ammonium ion binding
0.50	GO:0045296	cadherin binding
0.47	GO:0042802	identical protein binding
0.46	GO:0005509	calcium ion binding
0.39	GO:0043168	anion binding
0.34	GO:0019905	syntaxin binding
0.34	GO:0030276	clathrin binding
0.34	GO:0017137	Rab GTPase binding

0.52	GO:0044232	organelle membrane contact site
0.50	GO:0031227	intrinsic component of endoplasmic reticulum membrane
0.49	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.44	GO:0005887	integral component of plasma membrane
0.34	GO:0098793	presynapse
0.33	GO:0005634	nucleus

tr|T1FVE2|T1FVE2_HELRO
Uncharacterized protein
Search

0.10	Monocarboxylate transporter (Fragment)

0.55	GO:0055085	transmembrane transport
0.39	GO:0015718	monocarboxylic acid transport
0.36	GO:0015850	organic hydroxy compound transport
0.33	GO:0032392	DNA geometric change
0.32	GO:1901360	organic cyclic compound metabolic process
0.32	GO:0046483	heterocycle metabolic process
0.32	GO:0006725	cellular aromatic compound metabolic process
0.31	GO:0006807	nitrogen compound metabolic process
0.30	GO:0044238	primary metabolic process

0.40	GO:0008028	monocarboxylic acid transmembrane transporter activity
0.36	GO:1901618	organic hydroxy compound transmembrane transporter activity
0.34	GO:0015293	symporter activity
0.33	GO:0004003	ATP-dependent DNA helicase activity
0.32	GO:0005515	protein binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0003677	DNA binding
0.32	GO:0046872	metal ion binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.36	GO:0005887	integral component of plasma membrane
0.32	GO:0005634	nucleus
0.31	GO:0005737	cytoplasm

tr|T1FVE3|T1FVE3_HELRO
Uncharacterized protein
Search

0.66	DDHD domain containing 2

0.64	GO:0006888	ER to Golgi vesicle-mediated transport
0.46	GO:0007030	Golgi organization
0.37	GO:0016050	vesicle organization
0.37	GO:0007338	single fertilization
0.37	GO:0007286	spermatid development
0.36	GO:0010927	cellular component assembly involved in morphogenesis
0.35	GO:0070925	organelle assembly
0.35	GO:0048199	vesicle targeting, to, from or within Golgi
0.34	GO:0006886	intracellular protein transport
0.34	GO:0006461	protein complex assembly

0.54	GO:0046872	metal ion binding
0.45	GO:0004620	phospholipase activity
0.35	GO:0004806	triglyceride lipase activity
0.34	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.47	GO:0005794	Golgi apparatus
0.46	GO:0030134	COPII-coated ER to Golgi transport vesicle
0.37	GO:0070971	endoplasmic reticulum exit site
0.37	GO:0097038	perinuclear endoplasmic reticulum
0.36	GO:0005801	cis-Golgi network
0.36	GO:0030658	transport vesicle membrane
0.36	GO:0030660	Golgi-associated vesicle membrane
0.36	GO:0030662	coated vesicle membrane
0.35	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.34	GO:0005829	cytosol

0.45

EC:3.1.1

GO:0004620

tr|T1FVE4|T1FVE4_HELRO
Uncharacterized protein
Search

0.83	GO:0036297	interstrand cross-link repair
0.64	GO:0090305	nucleic acid phosphodiester bond hydrolysis

0.64	GO:0004518	nuclease activity
0.51	GO:0003676	nucleic acid binding
0.35	GO:0140097	catalytic activity, acting on DNA

0.37

GO:0005634

nucleus

0.64

GO:0004518

tr|T1FVE5|T1FVE5_HELRO
Uncharacterized protein
Search

tr|T1FVE6|T1FVE6_HELRO
Uncharacterized protein
Search

0.34	Global transcriptional regulator cell division control protein

0.62	GO:0051301	cell division
0.56	GO:0034724	DNA replication-independent nucleosome organization
0.54	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter
0.52	GO:0006368	transcription elongation from RNA polymerase II promoter
0.42	GO:0001672	regulation of chromatin assembly or disassembly
0.40	GO:0006281	DNA repair
0.37	GO:0006260	DNA replication

0.55	GO:0031491	nucleosome binding
0.53	GO:0042393	histone binding
0.41	GO:0047485	protein N-terminus binding
0.39	GO:0046982	protein heterodimerization activity
0.38	GO:0008094	DNA-dependent ATPase activity
0.35	GO:0030554	adenyl nucleotide binding
0.35	GO:0003677	DNA binding
0.35	GO:0032555	purine ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.58	GO:0035101	FACT complex
0.42	GO:0005703	polytene chromosome puff
0.42	GO:0005705	polytene chromosome interband
0.38	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|T1FVE7|T1FVE7_HELRO
Uncharacterized protein
Search

tr|T1FVE8|T1FVE8_HELRO
Uncharacterized protein
Search

ANKRD42

0.50	Ankyrin repeat domain-containing protein 42

0.68	GO:1900017	positive regulation of cytokine production involved in inflammatory response
0.64	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.52	GO:0006915	apoptotic process
0.45	GO:0006508	proteolysis
0.40	GO:0006468	protein phosphorylation
0.39	GO:0006744	ubiquinone biosynthetic process
0.38	GO:0009116	nucleoside metabolic process
0.35	GO:0055114	oxidation-reduction process

0.67	GO:0051059	NF-kappaB binding
0.53	GO:0004197	cysteine-type endopeptidase activity
0.41	GO:0004672	protein kinase activity
0.38	GO:0032559	adenyl ribonucleotide binding
0.38	GO:0008144	drug binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding

0.50	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.53

EC:3.4.22

GO:0004197

tr|T1FVE9|T1FVE9_HELRO
Uncharacterized protein
Search

TEKT1

0.52

Tektin 1

0.84	GO:0030317	flagellated sperm motility
0.79	GO:0060294	cilium movement involved in cell motility
0.78	GO:0060271	cilium assembly
0.74	GO:0080154	regulation of fertilization
0.43	GO:0098813	nuclear chromosome segregation
0.41	GO:0070193	synaptonemal complex organization
0.40	GO:0070192	chromosome organization involved in meiotic cell cycle
0.40	GO:0007127	meiosis I
0.39	GO:0000724	double-strand break repair via homologous recombination

0.83	GO:0036126	sperm flagellum
0.74	GO:0002080	acrosomal membrane
0.56	GO:0005634	nucleus
0.53	GO:0005874	microtubule
0.49	GO:0070062	extracellular exosome
0.43	GO:0000793	condensed chromosome
0.41	GO:0044427	chromosomal part
0.40	GO:0106068	SUMO ligase complex
0.37	GO:0043233	organelle lumen

tr|T1FVF0|T1FVF0_HELRO
Uncharacterized protein
Search

tr|T1FVF1|T1FVF1_HELRO
Uncharacterized protein
Search

RNF121

0.56	RING finger protein 121

0.47	GO:0030968	endoplasmic reticulum unfolded protein response
0.46	GO:0030433	ubiquitin-dependent ERAD pathway
0.44	GO:0001966	thigmotaxis
0.44	GO:1903069	regulation of ER-associated ubiquitin-dependent protein catabolic process
0.44	GO:0016567	protein ubiquitination
0.43	GO:0019228	neuronal action potential
0.42	GO:0072659	protein localization to plasma membrane
0.32	GO:0055114	oxidation-reduction process

0.45	GO:0061630	ubiquitin protein ligase activity
0.40	GO:0046872	metal ion binding
0.35	GO:0016874	ligase activity
0.34	GO:0005515	protein binding
0.33	GO:0050660	flavin adenine dinucleotide binding
0.32	GO:0016491	oxidoreductase activity

0.44	GO:0000139	Golgi membrane
0.44	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.35

GO:0016874

tr|T1FVF2|T1FVF2_HELRO
Uncharacterized protein
Search

0.47	GO:0008045	motor neuron axon guidance
0.46	GO:0035332	positive regulation of hippo signaling
0.44	GO:0006325	chromatin organization
0.43	GO:0018022	peptidyl-lysine methylation
0.43	GO:0010256	endomembrane system organization
0.42	GO:0060255	regulation of macromolecule metabolic process
0.42	GO:0051171	regulation of nitrogen compound metabolic process
0.42	GO:0080090	regulation of primary metabolic process
0.41	GO:0031326	regulation of cellular biosynthetic process
0.40	GO:0051641	cellular localization

0.45	GO:0003676	nucleic acid binding
0.42	GO:0005515	protein binding
0.40	GO:0046872	metal ion binding
0.37	GO:0043024	ribosomal small subunit binding
0.37	GO:0015574	trehalose transmembrane transporter activity
0.37	GO:0005487	structural constituent of nuclear pore
0.37	GO:0004107	chorismate synthase activity
0.36	GO:0003700	DNA binding transcription factor activity
0.35	GO:0004252	serine-type endopeptidase activity
0.35	GO:0043168	anion binding

0.50	GO:0005634	nucleus
0.45	GO:0070013	intracellular organelle lumen
0.43	GO:0044446	intracellular organelle part
0.42	GO:0034708	methyltransferase complex
0.40	GO:0012505	endomembrane system
0.39	GO:0010494	cytoplasmic stress granule
0.39	GO:0043234	protein complex
0.38	GO:0031248	protein acetyltransferase complex
0.38	GO:0000428	DNA-directed RNA polymerase complex
0.38	GO:1905368	peptidase complex

0.37	EC:4.2.3.5	GO:0004107
0.37	KEGG:R01714	GO:0004107

tr|T1FVF3|T1FVF3_HELRO
Uncharacterized protein
Search

0.83

GO:0090307

mitotic spindle assembly

0.38

GO:0016874

ligase activity

0.38

GO:0016874

tr|T1FVF4|T1FVF4_HELRO
Uncharacterized protein
Search

BCKDK

0.95	Branched chain alpha ketoacid dehydrogenase kinase

0.56	GO:0016310	phosphorylation
0.45	GO:0036211	protein modification process
0.43	GO:0044267	cellular protein metabolic process
0.41	GO:0009083	branched-chain amino acid catabolic process

0.56	GO:0016772	transferase activity, transferring phosphorus-containing groups
0.44	GO:0140096	catalytic activity, acting on a protein
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005515	protein binding

0.45	GO:0005739	mitochondrion
0.41	GO:0045240	dihydrolipoyl dehydrogenase complex
0.38	GO:0031974	membrane-enclosed lumen
0.36	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.56

EC:2.7

GO:0016772

tr|T1FVF5|T1FVF5_HELRO
Uncharacterized protein
Search

0.50	GO:0045600	positive regulation of fat cell differentiation
0.47	GO:0001934	positive regulation of protein phosphorylation
0.32	GO:0035335	peptidyl-tyrosine dephosphorylation
0.32	GO:0006886	intracellular protein transport

0.54	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding
0.32	GO:0004725	protein tyrosine phosphatase activity

0.48	GO:0005769	early endosome
0.30	GO:0016020	membrane

0.32

GO:0004725

tr|T1FVF6|T1FVF6_HELRO
Uncharacterized protein
Search

tr|T1FVF7|T1FVF7_HELRO
Uncharacterized protein
Search

0.67	GO:0060361	flight
0.66	GO:1903147	negative regulation of autophagy of mitochondrion
0.63	GO:0001751	compound eye photoreceptor cell differentiation
0.63	GO:0046427	positive regulation of JAK-STAT cascade
0.63	GO:0045214	sarcomere organization
0.63	GO:0019730	antimicrobial humoral response
0.58	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.58	GO:0043066	negative regulation of apoptotic process
0.57	GO:0007005	mitochondrion organization

0.58	GO:0019901	protein kinase binding
0.54	GO:0003723	RNA binding
0.44	GO:0032559	adenyl ribonucleotide binding
0.44	GO:0008144	drug binding
0.44	GO:0035639	purine ribonucleoside triphosphate binding

0.64	GO:0031430	M band
0.62	GO:0030018	Z disc

tr|T1FVF8|T1FVF8_HELRO
Uncharacterized protein
Search

0.80	SWI/SNF complex subunit SMARCC2

0.76

GO:0043044

ATP-dependent chromatin remodeling

0.55

GO:0003677

DNA binding

0.82	GO:0016514	SWI/SNF complex
0.53	GO:0071565	nBAF complex
0.53	GO:0071564	npBAF complex
0.30	GO:0031224	intrinsic component of membrane

tr|T1FVF9|T1FVF9_HELRO
Uncharacterized protein
Search

tr|T1FVG0|T1FVG0_HELRO
Uncharacterized protein
Search

0.45	GO:0060255	regulation of macromolecule metabolic process
0.44	GO:0031326	regulation of cellular biosynthetic process
0.44	GO:0051171	regulation of nitrogen compound metabolic process
0.44	GO:0080090	regulation of primary metabolic process
0.42	GO:0051568	histone H3-K4 methylation
0.41	GO:0007165	signal transduction
0.40	GO:0044093	positive regulation of molecular function
0.40	GO:0051289	protein homotetramerization
0.39	GO:0032870	cellular response to hormone stimulus
0.39	GO:0007275	multicellular organism development

0.44	GO:0046872	metal ion binding
0.43	GO:0140110	transcription regulator activity
0.43	GO:0003676	nucleic acid binding
0.42	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.41	GO:0008140	cAMP response element binding protein binding
0.38	GO:0017076	purine nucleotide binding
0.38	GO:0097367	carbohydrate derivative binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0050072	m7G(5')pppN diphosphatase activity
0.37	GO:0008047	enzyme activator activity

0.47	GO:0005634	nucleus
0.41	GO:0034708	methyltransferase complex
0.40	GO:0070013	intracellular organelle lumen
0.38	GO:0044446	intracellular organelle part
0.36	GO:0000932	P-body
0.36	GO:0034707	chloride channel complex
0.35	GO:0044815	DNA packaging complex
0.35	GO:0032993	protein-DNA complex
0.35	GO:0005694	chromosome
0.34	GO:0043234	protein complex

0.37	EC:3.6.1.30	GO:0050072
0.37	KEGG:R00472	GO:0004474

tr|T1FVG1|T1FVG1_HELRO
Uncharacterized protein
Search

tr|T1FVG2|T1FVG2_HELRO
Uncharacterized protein
Search

tr|T1FVG3|T1FVG3_HELRO
Uncharacterized protein
Search

0.81	GO:0032456	endocytic recycling
0.77	GO:0042147	retrograde transport, endosome to Golgi
0.72	GO:0007041	lysosomal transport
0.66	GO:0006914	autophagy
0.66	GO:0007030	Golgi organization
0.61	GO:0048193	Golgi vesicle transport
0.48	GO:0006869	lipid transport
0.44	GO:0015031	protein transport
0.41	GO:0044241	lipid digestion
0.40	GO:0010517	regulation of phospholipase activity

0.43	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
0.40	GO:0030306	ADP-ribosylation factor binding
0.38	GO:0000033	alpha-1,3-mannosyltransferase activity
0.38	GO:0005549	odorant binding
0.37	GO:0004984	olfactory receptor activity

0.85	GO:1990745	EARP complex
0.85	GO:0000938	GARP complex
0.66	GO:0005829	cytosol
0.63	GO:0005730	nucleolus
0.44	GO:0005802	trans-Golgi network
0.38	GO:0000139	Golgi membrane
0.36	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

0.43

EC:1.3.1

GO:0016628

tr|T1FVG4|T1FVG4_HELRO
Uncharacterized protein
Search

tr|T1FVG5|T1FVG5_HELRO
Uncharacterized protein
Search

DYNC2LI1

0.64	Cytoplasmic dynein 2 light intermediate chain 1

0.86	GO:0035721	intraciliary retrograde transport
0.86	GO:0035735	intraciliary transport involved in cilium assembly

0.86	GO:0045504	dynein heavy chain binding
0.85	GO:0008569	ATP-dependent microtubule motor activity, minus-end-directed

0.83	GO:0005868	cytoplasmic dynein complex
0.83	GO:0036064	ciliary basal body
0.82	GO:0005930	axoneme

0.85

EC:3.6.4.5

GO:0008569

tr|T1FVG6|T1FVG6_HELRO
Uncharacterized protein
Search

0.55	GO:0043153	entrainment of circadian clock by photoperiod
0.53	GO:0032922	circadian regulation of gene expression
0.51	GO:0032055	negative regulation of translation in response to stress
0.51	GO:0002192	IRES-dependent translational initiation of linear mRNA
0.50	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.49	GO:0048518	positive regulation of biological process
0.49	GO:0046822	regulation of nucleocytoplasmic transport
0.49	GO:0035278	miRNA mediated inhibition of translation
0.49	GO:0051147	regulation of muscle cell differentiation
0.48	GO:0045947	negative regulation of translational initiation

0.61	GO:0008270	zinc ion binding
0.59	GO:0003723	RNA binding
0.47	GO:0030332	cyclin binding
0.33	GO:0003682	chromatin binding

0.49	GO:0005654	nucleoplasm
0.49	GO:0005829	cytosol
0.47	GO:0010494	cytoplasmic stress granule
0.47	GO:0005730	nucleolus
0.41	GO:0043234	protein complex
0.39	GO:0048471	perinuclear region of cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1FVG7|T1FVG7_HELRO
Uncharacterized protein
Search

tr|T1FVG8|T1FVG8_HELRO
Uncharacterized protein
Search

0.11	Calcium-transporting ATPase

0.76	GO:0070588	calcium ion transmembrane transport
0.68	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.45	GO:1990034	calcium ion export across plasma membrane
0.45	GO:0006874	cellular calcium ion homeostasis

0.79	GO:0005388	calcium-transporting ATPase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0030165	PDZ domain binding
0.37	GO:0005516	calmodulin binding
0.32	GO:0020037	heme binding

0.40	GO:0005794	Golgi apparatus
0.37	GO:0005887	integral component of plasma membrane

0.79

EC:3.6.3.8

GO:0005388

tr|T1FVG9|T1FVG9_HELRO
Uncharacterized protein
Search

0.57	GO:0006458	'de novo' protein folding
0.56	GO:0042147	retrograde transport, endosome to Golgi
0.55	GO:0061077	chaperone-mediated protein folding
0.54	GO:0006694	steroid biosynthetic process
0.53	GO:0046854	phosphatidylinositol phosphorylation
0.42	GO:0055114	oxidation-reduction process

0.61	GO:0000285	1-phosphatidylinositol-3-phosphate 5-kinase activity
0.59	GO:0044183	protein binding involved in protein folding
0.56	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity
0.51	GO:0051082	unfolded protein binding
0.43	GO:0032559	adenyl ribonucleotide binding
0.42	GO:0008144	drug binding
0.42	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0046872	metal ion binding

0.55	GO:0010008	endosome membrane
0.50	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.61	EC:2.7.1.150	GO:0000285
0.61	KEGG:R05802	GO:0000285

tr|T1FVH0|T1FVH0_HELRO
Uncharacterized protein
Search

tr|T1FVH1|T1FVH1_HELRO
Uncharacterized protein
Search

tr|T1FVH2|T1FVH2_HELRO
Uncharacterized protein
Search

tr|T1FVH3|T1FVH3_HELRO
Uncharacterized protein
Search

SELENOT

0.95	Selenoprotein t

0.57	GO:0035773	insulin secretion involved in cellular response to glucose stimulus
0.53	GO:0031016	pancreas development
0.47	GO:0045454	cell redox homeostasis
0.42	GO:0060124	positive regulation of growth hormone secretion
0.40	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.38	GO:0098869	cellular oxidant detoxification
0.35	GO:0055114	oxidation-reduction process
0.34	GO:0001514	selenocysteine incorporation

0.40	GO:0004791	thioredoxin-disulfide reductase activity
0.35	GO:0008430	selenium binding
0.32	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.32	GO:0020037	heme binding
0.32	GO:0005506	iron ion binding

0.48	GO:0005783	endoplasmic reticulum
0.39	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.38	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.40	EC:1.8.1.9	GO:0004791
0.40	KEGG:R02016	GO:0004791

tr|T1FVH4|T1FVH4_HELRO
Uncharacterized protein
Search

0.69	GO:0010923	negative regulation of phosphatase activity
0.40	GO:0009966	regulation of signal transduction
0.40	GO:0006030	chitin metabolic process
0.39	GO:0042051	compound eye photoreceptor development
0.37	GO:0019310	inositol catabolic process
0.37	GO:0023057	negative regulation of signaling
0.37	GO:0010648	negative regulation of cell communication
0.37	GO:0006396	RNA processing
0.37	GO:0007283	spermatogenesis
0.36	GO:0048585	negative regulation of response to stimulus

0.70	GO:0019902	phosphatase binding
0.40	GO:0008061	chitin binding
0.38	GO:0050113	inositol oxygenase activity
0.38	GO:0008083	growth factor activity
0.38	GO:0030159	receptor signaling complex scaffold activity
0.37	GO:0050825	ice binding
0.37	GO:0046872	metal ion binding
0.36	GO:0004222	metalloendopeptidase activity
0.36	GO:0003723	RNA binding
0.35	GO:0008017	microtubule binding

0.59	GO:0005829	cytosol
0.39	GO:0005634	nucleus
0.39	GO:0019898	extrinsic component of membrane
0.38	GO:0005576	extracellular region
0.38	GO:1905360	GTPase complex
0.37	GO:0043234	protein complex
0.37	GO:0009898	cytoplasmic side of plasma membrane
0.37	GO:0012505	endomembrane system
0.36	GO:0044446	intracellular organelle part
0.36	GO:0048475	coated membrane

0.38	EC:1.13.99.1	GO:0050113
0.38	KEGG:R01184	GO:0050113

tr|T1FVH5|T1FVH5_HELRO
Uncharacterized protein
Search

0.50	GO:0035518	histone H2A monoubiquitination
0.49	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process
0.46	GO:0000122	negative regulation of transcription by RNA polymerase II
0.46	GO:0043065	positive regulation of apoptotic process
0.44	GO:0045893	positive regulation of transcription, DNA-templated
0.37	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
0.37	GO:0006915	apoptotic process
0.37	GO:0043066	negative regulation of apoptotic process
0.36	GO:0050777	negative regulation of immune response
0.35	GO:0070317	negative regulation of G0 to G1 transition

0.54	GO:0046872	metal ion binding
0.50	GO:0003714	transcription corepressor activity
0.40	GO:0003713	transcription coactivator activity
0.39	GO:0003677	DNA binding
0.34	GO:0005515	protein binding

0.48	GO:0031519	PcG protein complex
0.45	GO:0005654	nucleoplasm
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|T1FVH6|T1FVH6_HELRO
Uncharacterized protein
Search

tr|T1FVH7|T1FVH7_HELRO
Uncharacterized protein
Search

tr|T1FVH8|T1FVH8_HELRO
Uncharacterized protein
Search

0.63	GO:0015937	coenzyme A biosynthetic process
0.50	GO:0016310	phosphorylation
0.46	GO:0019985	translesion synthesis
0.44	GO:0016573	histone acetylation
0.41	GO:0006289	nucleotide-excision repair
0.38	GO:0006511	ubiquitin-dependent protein catabolic process
0.36	GO:0007367	segment polarity determination
0.36	GO:0042067	establishment of ommatidial planar polarity
0.36	GO:0045879	negative regulation of smoothened signaling pathway
0.36	GO:0006629	lipid metabolic process

0.66	GO:0004594	pantothenate kinase activity
0.48	GO:0030554	adenyl nucleotide binding
0.48	GO:0097367	carbohydrate derivative binding
0.48	GO:0008144	drug binding
0.48	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0004402	histone acetyltransferase activity
0.42	GO:0003887	DNA-directed DNA polymerase activity
0.41	GO:0003684	damaged DNA binding
0.38	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity
0.37	GO:0008081	phosphoric diester hydrolase activity

0.47	GO:0016035	zeta DNA polymerase complex
0.39	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.66

EC:2.7.1.33

GO:0004594

tr|T1FVH9|T1FVH9_HELRO
Uncharacterized protein
Search

tr|T1FVI0|T1FVI0_HELRO
Uncharacterized protein
Search

tr|T1FVI1|T1FVI1_HELRO
Uncharacterized protein
Search

tr|T1FVI2|T1FVI2_HELRO
Uncharacterized protein
Search

0.43	GO:1904005	regulation of phospholipase D activity
0.43	GO:0110014	negative regulation of aggregation involved in sorocarp development
0.42	GO:0048837	sorocarp sorus development
0.41	GO:0010518	positive regulation of phospholipase activity
0.40	GO:0019933	cAMP-mediated signaling
0.39	GO:0009372	quorum sensing
0.39	GO:0030833	regulation of actin filament polymerization
0.39	GO:0022407	regulation of cell-cell adhesion
0.38	GO:0036211	protein modification process
0.38	GO:0060255	regulation of macromolecule metabolic process

0.42	GO:0005199	structural constituent of cell wall
0.39	GO:0004674	protein serine/threonine kinase activity
0.37	GO:0008061	chitin binding
0.37	GO:0004722	protein serine/threonine phosphatase activity
0.36	GO:0004871	signal transducer activity
0.36	GO:0003700	DNA binding transcription factor activity
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0005509	calcium ion binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0003676	nucleic acid binding

0.60	GO:0005856	cytoskeleton
0.42	GO:0070701	mucus layer
0.40	GO:0005618	cell wall
0.35	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.39

GO:0004674

tr|T1FVI3|T1FVI3_HELRO
Uncharacterized protein
Search

tr|T1FVI4|T1FVI4_HELRO
Uncharacterized protein
Search

tr|T1FVI5|T1FVI5_HELRO
Uncharacterized protein
Search

tr|T1FVI6|T1FVI6_HELRO
Uncharacterized protein
Search

0.55	GO:0055085	transmembrane transport
0.41	GO:0006833	water transport
0.37	GO:0006811	ion transport
0.36	GO:0046331	lateral inhibition
0.36	GO:0044719	regulation of imaginal disc-derived wing size
0.36	GO:0007398	ectoderm development
0.36	GO:0030707	ovarian follicle cell development
0.36	GO:0007498	mesoderm development
0.35	GO:0007219	Notch signaling pathway
0.35	GO:0098609	cell-cell adhesion

0.69	GO:0015267	channel activity
0.42	GO:0005372	water transmembrane transporter activity
0.33	GO:0008324	cation transmembrane transporter activity
0.32	GO:0003676	nucleic acid binding

0.43	GO:0042807	central vacuole
0.42	GO:0009705	plant-type vacuole membrane
0.38	GO:0005887	integral component of plasma membrane
0.35	GO:0005912	adherens junction
0.34	GO:0031410	cytoplasmic vesicle

tr|T1FVI7|T1FVI7_HELRO
Uncharacterized protein
Search

tr|T1FVI8|T1FVI8_HELRO
Uncharacterized protein
Search

tr|T1FVI9|T1FVI9_HELRO
Uncharacterized protein
Search

0.10	Myosin-Ib (Fragment)

0.73	GO:0007018	microtubule-based movement
0.49	GO:0006892	post-Golgi vesicle-mediated transport
0.47	GO:0007015	actin filament organization
0.45	GO:0030048	actin filament-based movement
0.40	GO:0022607	cellular component assembly
0.36	GO:0033572	transferrin transport
0.34	GO:0007399	nervous system development

0.74	GO:0003777	microtubule motor activity
0.73	GO:0008017	microtubule binding
0.73	GO:0003779	actin binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0000146	microfilament motor activity
0.49	GO:0045296	cadherin binding
0.47	GO:0032403	protein complex binding
0.46	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding

0.77	GO:0016459	myosin complex
0.51	GO:0032588	trans-Golgi network membrane
0.50	GO:0005884	actin filament
0.49	GO:0005769	early endosome
0.48	GO:0048471	perinuclear region of cytoplasm
0.48	GO:0010008	endosome membrane
0.45	GO:0030175	filopodium
0.45	GO:0005903	brush border
0.40	GO:0005886	plasma membrane
0.37	GO:0045177	apical part of cell

tr|T1FVJ0|T1FVJ0_HELRO
Uncharacterized protein
Search

tr|T1FVJ1|T1FVJ1_HELRO
Uncharacterized protein
Search

0.42	GO:0048731	system development
0.42	GO:0071495	cellular response to endogenous stimulus
0.41	GO:0071310	cellular response to organic substance
0.41	GO:1905167	positive regulation of lysosomal protein catabolic process
0.41	GO:1900223	positive regulation of amyloid-beta clearance
0.41	GO:0071772	response to BMP
0.41	GO:0097242	amyloid-beta clearance
0.40	GO:0061900	glial cell activation
0.40	GO:0006898	receptor-mediated endocytosis
0.40	GO:0060828	regulation of canonical Wnt signaling pathway

0.65	GO:0005509	calcium ion binding
0.43	GO:0016964	alpha-2 macroglobulin receptor activity
0.41	GO:0032050	clathrin heavy chain binding
0.41	GO:0034185	apolipoprotein binding
0.40	GO:0004252	serine-type endopeptidase activity
0.38	GO:0032403	protein complex binding
0.38	GO:0005044	scavenger receptor activity
0.35	GO:0004930	G-protein coupled receptor activity
0.34	GO:0008083	growth factor activity
0.34	GO:0031419	cobalamin binding

0.42	GO:0012505	endomembrane system
0.39	GO:0016323	basolateral plasma membrane
0.38	GO:0043235	receptor complex
0.38	GO:0043227	membrane-bounded organelle
0.38	GO:0044444	cytoplasmic part
0.37	GO:0043229	intracellular organelle
0.36	GO:0005604	basement membrane
0.35	GO:0098589	membrane region
0.33	GO:0005887	integral component of plasma membrane

0.40

GO:0004252

tr|T1FVJ2|T1FVJ2_HELRO
Uncharacterized protein
Search

0.52	GO:0055114	oxidation-reduction process
0.36	GO:0006979	response to oxidative stress
0.34	GO:0006996	organelle organization
0.34	GO:0018393	internal peptidyl-lysine acetylation
0.34	GO:0065009	regulation of molecular function
0.33	GO:0032012	regulation of ARF protein signal transduction
0.33	GO:0006261	DNA-dependent DNA replication
0.33	GO:1902358	sulfate transmembrane transport
0.33	GO:0007017	microtubule-based process
0.33	GO:0098869	cellular oxidant detoxification

0.74	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity
0.64	GO:0051287	NAD binding
0.40	GO:0008679	2-hydroxy-3-oxopropionate reductase activity
0.37	GO:0003858	3-hydroxybutyrate dehydrogenase activity
0.34	GO:0098772	molecular function regulator
0.34	GO:0061505	DNA topoisomerase II activity
0.34	GO:0008237	metallopeptidase activity
0.34	GO:0042623	ATPase activity, coupled
0.34	GO:0008271	secondary active sulfate transmembrane transporter activity
0.33	GO:0046872	metal ion binding

0.35	GO:0005829	cytosol
0.34	GO:0043229	intracellular organelle
0.34	GO:0043227	membrane-bounded organelle
0.34	GO:1902493	acetyltransferase complex
0.33	GO:0043228	non-membrane-bounded organelle
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.32	GO:0044422	organelle part
0.30	GO:0016020	membrane

0.74	EC:1.1.1.44	GO:0004616
0.37	KEGG:R01361	GO:0003858

tr|T1FVJ3|T1FVJ3_HELRO
Uncharacterized protein
Search

tr|T1FVJ4|T1FVJ4_HELRO
Uncharacterized protein
Search

0.71	Mitochondrial glutamate carrier 2

0.52	GO:0055085	transmembrane transport
0.45	GO:0015813	L-glutamate transport
0.38	GO:0006839	mitochondrial transport
0.33	GO:0005975	carbohydrate metabolic process
0.33	GO:0019752	carboxylic acid metabolic process
0.32	GO:0055114	oxidation-reduction process

0.48	GO:0005314	high-affinity glutamate transmembrane transporter activity
0.34	GO:0004459	L-lactate dehydrogenase activity

0.36	GO:0031966	mitochondrial membrane
0.36	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.34

EC:1.1.1.27

GO:0004459

tr|T1FVJ5|T1FVJ5_HELRO
Uncharacterized protein
Search

tr|T1FVJ6|T1FVJ6_HELRO
Uncharacterized protein
Search

tr|T1FVJ7|T1FVJ7_HELRO
Uncharacterized protein
Search

0.74

GO:0008017

microtubule binding

tr|T1FVJ8|T1FVJ8_HELRO
Uncharacterized protein
Search

0.57	GO:0016310	phosphorylation
0.51	GO:0030258	lipid modification
0.50	GO:0045039	protein import into mitochondrial inner membrane
0.50	GO:0046513	ceramide biosynthetic process
0.44	GO:0008654	phospholipid biosynthetic process
0.37	GO:0007280	pole cell migration
0.35	GO:0046486	glycerolipid metabolic process
0.32	GO:0006002	fructose 6-phosphate metabolic process
0.32	GO:0046031	ADP metabolic process
0.32	GO:0006090	pyruvate metabolic process

0.76	GO:0003951	NAD+ kinase activity
0.58	GO:0001727	lipid kinase activity
0.42	GO:0000287	magnesium ion binding
0.39	GO:0032559	adenyl ribonucleotide binding
0.39	GO:0008144	drug binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0004143	diacylglycerol kinase activity
0.39	GO:0047620	acylglycerol kinase activity
0.32	GO:0003872	6-phosphofructokinase activity
0.32	GO:0003723	RNA binding

0.50	GO:0042721	mitochondrial inner membrane protein insertion complex
0.49	GO:0031305	integral component of mitochondrial inner membrane
0.48	GO:0005758	mitochondrial intermembrane space
0.34	GO:0005741	mitochondrial outer membrane
0.33	GO:0005829	cytosol
0.33	GO:0005634	nucleus

0.76	EC:2.7.1.23	GO:0003951
0.76	KEGG:R00104	GO:0003951

tr|T1FVJ9|T1FVJ9_HELRO
Uncharacterized protein
Search

0.36

GO:0005975

carbohydrate metabolic process

0.54	GO:0003677	DNA binding
0.38	GO:0030246	carbohydrate binding
0.38	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.60	GO:0005634	nucleus
0.38	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.38

GO:0004553

tr|T1FVK0|T1FVK0_HELRO
Uncharacterized protein
Search

tr|T1FVK1|T1FVK1_HELRO
Uncharacterized protein
Search

tr|T1FVK2|T1FVK2_HELRO
Uncharacterized protein
Search

tr|T1FVK3|T1FVK3_HELRO
Uncharacterized protein
Search

tr|T1FVK4|T1FVK4_HELRO
Uncharacterized protein
Search

0.50	GO:0021799	cerebral cortex radially oriented cell migration
0.50	GO:0051642	centrosome localization

0.61

GO:0005509

calcium ion binding

0.46	GO:0005813	centrosome
0.37	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

tr|T1FVK5|T1FVK5_HELRO
Uncharacterized protein
Search

ALDH2

0.37	Aldehyde dehydrogenase, mitochondrial

0.53	GO:0055114	oxidation-reduction process
0.39	GO:0006068	ethanol catabolic process
0.39	GO:2001038	regulation of cellular response to drug
0.36	GO:0006081	cellular aldehyde metabolic process
0.35	GO:0006470	protein dephosphorylation
0.33	GO:0006468	protein phosphorylation
0.33	GO:0005975	carbohydrate metabolic process
0.33	GO:0006091	generation of precursor metabolites and energy

0.69	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.36	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.36	GO:0051287	NAD binding
0.34	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors
0.34	GO:0050660	flavin adenine dinucleotide binding
0.34	GO:0004462	lactoylglutathione lyase activity
0.33	GO:0009055	electron transfer activity
0.33	GO:0004672	protein kinase activity
0.32	GO:0046872	metal ion binding
0.32	GO:0005524	ATP binding

0.39	GO:0005739	mitochondrion
0.36	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part
0.34	GO:0070062	extracellular exosome

0.69	EC:1.2.1	GO:0016620
0.34	KEGG:R02530	GO:0004462

tr|T1FVK6|T1FVK6_HELRO
Uncharacterized protein
Search

tr|T1FVK7|T1FVK7_HELRO
Uncharacterized protein
Search

tr|T1FVK8|T1FVK8_HELRO
Uncharacterized protein
Search

tr|T1FVK9|T1FVK9_HELRO
Uncharacterized protein
Search

tr|T1FVL0|T1FVL0_HELRO
Uncharacterized protein
Search

0.85	GO:0031591	wybutosine biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.33	GO:0032259	methylation

0.80	GO:0016706	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
0.69	GO:0000049	tRNA binding
0.48	GO:0042803	protein homodimerization activity
0.43	GO:0005506	iron ion binding
0.35	GO:0140101	catalytic activity, acting on a tRNA
0.33	GO:0008168	methyltransferase activity

0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.80

EC:1.14.11

GO:0016706

tr|T1FVL1|T1FVL1_HELRO
Uncharacterized protein
Search

tr|T1FVL2|T1FVL2_HELRO
Battenin
Search

0.44

Battenin

0.45	GO:0007040	lysosome organization
0.44	GO:0008340	determination of adult lifespan
0.42	GO:0030003	cellular cation homeostasis
0.42	GO:0015809	arginine transport
0.41	GO:0001932	regulation of protein phosphorylation
0.41	GO:0098771	inorganic ion homeostasis
0.41	GO:0008593	regulation of Notch signaling pathway
0.41	GO:0043524	negative regulation of neuron apoptotic process
0.41	GO:0070302	regulation of stress-activated protein kinase signaling cascade
0.41	GO:0097352	autophagosome maturation

0.40	GO:0048306	calcium-dependent protein binding
0.33	GO:0051082	unfolded protein binding

0.72	GO:0005765	lysosomal membrane
0.44	GO:0005770	late endosome
0.42	GO:0031528	microvillus membrane
0.40	GO:0005769	early endosome
0.40	GO:0016324	apical plasma membrane
0.40	GO:0005776	autophagosome
0.37	GO:0005901	caveola
0.37	GO:0005739	mitochondrion
0.36	GO:0031967	organelle envelope
0.36	GO:0008021	synaptic vesicle

tr|T1FVL3|T1FVL3_HELRO
Uncharacterized protein
Search

0.77	Novel zinc knuckle containing protein (Ortholog of human step II splicing factor SLU7) (Fragment)

0.60	GO:0000375	RNA splicing, via transesterification reactions
0.49	GO:0034605	cellular response to heat
0.46	GO:0022618	ribonucleoprotein complex assembly
0.45	GO:0006397	mRNA processing
0.45	GO:0006886	intracellular protein transport
0.37	GO:0007165	signal transduction
0.34	GO:0006369	termination of RNA polymerase II transcription
0.34	GO:0071166	ribonucleoprotein complex localization
0.34	GO:0051169	nuclear transport
0.34	GO:0031123	RNA 3'-end processing

0.69	GO:0000386	second spliceosomal transesterification activity
0.55	GO:0008270	zinc ion binding
0.52	GO:0030628	pre-mRNA 3'-splice site binding
0.39	GO:0005509	calcium ion binding
0.38	GO:0016787	hydrolase activity
0.33	GO:0005515	protein binding
0.32	GO:0016740	transferase activity

0.60	GO:0005681	spliceosomal complex
0.48	GO:0016607	nuclear speck
0.48	GO:0030532	small nuclear ribonucleoprotein complex
0.44	GO:0005829	cytosol
0.42	GO:1902494	catalytic complex
0.41	GO:0005578	proteinaceous extracellular matrix
0.40	GO:0005615	extracellular space
0.30	GO:0016020	membrane

0.38

GO:0016787

tr|T1FVL4|T1FVL4_HELRO
Uncharacterized protein
Search

tr|T1FVL5|T1FVL5_HELRO
Methyltransferase-like protein
Search

METTL16

0.41	Methyltransferase 10 domain containing (Fragment)

0.63	GO:0032259	methylation
0.55	GO:0120049	snRNA (adenine-N6)-methylation
0.51	GO:0061157	mRNA destabilization
0.50	GO:0048024	regulation of mRNA splicing, via spliceosome
0.49	GO:0016556	mRNA modification
0.46	GO:0006402	mRNA catabolic process
0.42	GO:0000154	rRNA modification
0.37	GO:0008380	RNA splicing
0.37	GO:0006397	mRNA processing
0.36	GO:0000132	establishment of mitotic spindle orientation

0.63	GO:0008168	methyltransferase activity
0.55	GO:0030629	U6 snRNA 3'-end binding
0.53	GO:0035613	RNA stem-loop binding
0.44	GO:0140098	catalytic activity, acting on RNA
0.36	GO:0070840	dynein complex binding
0.35	GO:0003887	DNA-directed DNA polymerase activity
0.33	GO:0003677	DNA binding
0.33	GO:0046983	protein dimerization activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding

0.43	GO:0005634	nucleus
0.35	GO:0005875	microtubule associated complex
0.35	GO:0005815	microtubule organizing center
0.35	GO:0005874	microtubule
0.33	GO:0034707	chloride channel complex
0.32	GO:0005737	cytoplasm

0.63

GO:0008168

tr|T1FVL6|T1FVL6_HELRO
Uncharacterized protein
Search

0.56	GO:0006898	receptor-mediated endocytosis
0.49	GO:0006508	proteolysis
0.47	GO:0048268	clathrin coat assembly
0.45	GO:0007377	germ-band extension
0.44	GO:2000369	regulation of clathrin-dependent endocytosis
0.43	GO:0048592	eye morphogenesis
0.42	GO:0007411	axon guidance
0.42	GO:0009405	pathogenesis
0.41	GO:0045944	positive regulation of transcription by RNA polymerase II
0.40	GO:0045892	negative regulation of transcription, DNA-templated

0.62	GO:0005044	scavenger receptor activity
0.54	GO:0004252	serine-type endopeptidase activity
0.48	GO:0005545	1-phosphatidylinositol binding
0.47	GO:0030276	clathrin binding
0.45	GO:0050825	ice binding
0.39	GO:0032550	purine ribonucleoside binding
0.39	GO:0032561	guanyl ribonucleotide binding
0.39	GO:0043565	sequence-specific DNA binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0003700	DNA binding transcription factor activity

0.46	GO:0030136	clathrin-coated vesicle
0.39	GO:0005829	cytosol
0.39	GO:0005576	extracellular region
0.38	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.54

GO:0004252

tr|T1FVL7|T1FVL7_HELRO
Uncharacterized protein
Search

0.49	GO:0036211	protein modification process
0.46	GO:0044267	cellular protein metabolic process
0.45	GO:0016569	covalent chromatin modification
0.44	GO:0015031	protein transport
0.43	GO:0051726	regulation of cell cycle
0.43	GO:0043414	macromolecule methylation
0.40	GO:0007458	progression of morphogenetic furrow involved in compound eye morphogenesis
0.40	GO:1900114	positive regulation of histone H3-K9 trimethylation
0.40	GO:0035332	positive regulation of hippo signaling
0.40	GO:1903506	regulation of nucleic acid-templated transcription

0.47	GO:0031151	histone methyltransferase activity (H3-K79 specific)
0.43	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.41	GO:0140110	transcription regulator activity
0.40	GO:0019787	ubiquitin-like protein transferase activity
0.40	GO:0032559	adenyl ribonucleotide binding
0.39	GO:0008144	drug binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.38	GO:0003676	nucleic acid binding
0.37	GO:0004003	ATP-dependent DNA helicase activity

0.46	GO:0005634	nucleus
0.43	GO:0031974	membrane-enclosed lumen
0.42	GO:0030686	90S preribosome
0.42	GO:0005732	small nucleolar ribonucleoprotein complex
0.41	GO:1990234	transferase complex
0.40	GO:0044446	intracellular organelle part
0.39	GO:0005700	polytene chromosome
0.39	GO:0043234	protein complex
0.38	GO:0005768	endosome
0.38	GO:1905368	peptidase complex

0.43

GO:0004715

tr|T1FVL8|T1FVL8_HELRO
Uncharacterized protein
Search

tr|T1FVL9|T1FVL9_HELRO
Uncharacterized protein
Search

tr|T1FVM0|T1FVM0_HELRO
Uncharacterized protein
Search

0.48	GO:0000122	negative regulation of transcription by RNA polymerase II
0.41	GO:0048733	sebaceous gland development
0.37	GO:0006325	chromatin organization
0.36	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter
0.36	GO:0043412	macromolecule modification
0.36	GO:0003006	developmental process involved in reproduction
0.36	GO:0031338	regulation of vesicle fusion
0.36	GO:0090630	activation of GTPase activity
0.35	GO:0042493	response to drug
0.35	GO:0006351	transcription, DNA-templated

0.40	GO:0140034	methylation-dependent protein binding
0.39	GO:0042393	histone binding
0.39	GO:0003727	single-stranded RNA binding
0.39	GO:0003682	chromatin binding
0.36	GO:0017016	Ras GTPase binding
0.36	GO:0003700	DNA binding transcription factor activity
0.35	GO:0000829	inositol heptakisphosphate kinase activity
0.35	GO:0005096	GTPase activator activity
0.34	GO:0003677	DNA binding
0.34	GO:0016773	phosphotransferase activity, alcohol group as acceptor

0.58	GO:0005634	nucleus
0.47	GO:0000785	chromatin
0.45	GO:0005829	cytosol
0.45	GO:0031974	membrane-enclosed lumen
0.42	GO:0043234	protein complex
0.40	GO:0000151	ubiquitin ligase complex
0.34	GO:0033202	DNA helicase complex
0.34	GO:0012505	endomembrane system
0.33	GO:1904949	ATPase complex
0.30	GO:0016020	membrane

0.34

GO:0016773

tr|T1FVM1|T1FVM1_HELRO
Uncharacterized protein
Search

tr|T1FVM2|T1FVM2_HELRO
Uncharacterized protein
Search

tr|T1FVM3|T1FVM3_HELRO
Uncharacterized protein
Search

tr|T1FVM4|T1FVM4_HELRO
Uncharacterized protein
Search

0.74	GO:0007018	microtubule-based movement
0.56	GO:0036159	inner dynein arm assembly
0.42	GO:0006072	glycerol-3-phosphate metabolic process
0.42	GO:0007605	sensory perception of sound
0.41	GO:0071910	determination of liver left/right asymmetry
0.36	GO:0055114	oxidation-reduction process
0.35	GO:0060285	cilium-dependent cell motility
0.33	GO:0061817	endoplasmic reticulum-plasma membrane tethering
0.33	GO:0006468	protein phosphorylation
0.33	GO:0006869	lipid transport

0.75	GO:0003777	microtubule motor activity
0.59	GO:0005509	calcium ion binding
0.53	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0045503	dynein light chain binding
0.50	GO:0051959	dynein light intermediate chain binding
0.50	GO:0045505	dynein intermediate chain binding
0.43	GO:0004368	glycerol-3-phosphate dehydrogenase activity
0.43	GO:0016887	ATPase activity

0.79	GO:0030286	dynein complex
0.55	GO:0044447	axoneme part
0.45	GO:0005829	cytosol
0.43	GO:0009331	glycerol-3-phosphate dehydrogenase complex
0.35	GO:0005874	microtubule
0.30	GO:0016021	integral component of membrane

0.43

EC:1.1.5.3

GO:0004368

tr|T1FVM5|T1FVM5_HELRO
Uncharacterized protein
Search

tr|T1FVM6|T1FVM6_HELRO
Uncharacterized protein
Search

tr|T1FVM7|T1FVM7_HELRO
Uncharacterized protein
Search

0.48	GO:0007165	signal transduction
0.45	GO:0016567	protein ubiquitination
0.44	GO:0048203	vesicle targeting, trans-Golgi to endosome
0.44	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading
0.43	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation
0.42	GO:2000146	negative regulation of cell motility
0.40	GO:0045732	positive regulation of protein catabolic process
0.39	GO:0034220	ion transmembrane transport

0.61	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.44	GO:0035650	AP-1 adaptor complex binding
0.42	GO:0005216	ion channel activity
0.40	GO:0019706	protein-cysteine S-palmitoyltransferase activity
0.39	GO:0030151	molybdenum ion binding
0.39	GO:0004842	ubiquitin-protein transferase activity
0.38	GO:0070279	vitamin B6 binding
0.37	GO:0008270	zinc ion binding
0.36	GO:0003723	RNA binding
0.36	GO:0050662	coenzyme binding

0.39	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.61	EC:2.4.2.30	GO:0003950
0.39	KEGG:R03876	GO:0004842

tr|T1FVM8|T1FVM8_HELRO
Uncharacterized protein
Search

tr|T1FVM9|T1FVM9_HELRO
Uncharacterized protein
Search

tr|T1FVN0|T1FVN0_HELRO
Uncharacterized protein
Search

0.49	GO:0030223	neutrophil differentiation
0.46	GO:0030225	macrophage differentiation
0.46	GO:0060218	hematopoietic stem cell differentiation
0.38	GO:0030902	hindbrain development
0.38	GO:0009952	anterior/posterior pattern specification
0.37	GO:0000122	negative regulation of transcription by RNA polymerase II
0.35	GO:0006325	chromatin organization
0.34	GO:0006476	protein deacetylation
0.34	GO:0006351	transcription, DNA-templated
0.33	GO:0007616	long-term memory

0.54	GO:0003677	DNA binding
0.39	GO:0016922	ligand-dependent nuclear receptor binding
0.37	GO:0003714	transcription corepressor activity
0.34	GO:0032041	NAD-dependent histone deacetylase activity (H3-K14 specific)
0.33	GO:0050825	ice binding
0.33	GO:0051082	unfolded protein binding
0.33	GO:0003700	DNA binding transcription factor activity
0.33	GO:0046872	metal ion binding
0.33	GO:0043141	ATP-dependent 5'-3' DNA helicase activity
0.33	GO:0001104	RNA polymerase II transcription cofactor activity

0.60	GO:0005634	nucleus
0.37	GO:0031974	membrane-enclosed lumen
0.36	GO:1902494	catalytic complex
0.35	GO:0044446	intracellular organelle part
0.33	GO:0005694	chromosome
0.33	GO:0097255	R2TP complex
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0032041

tr|T1FVN1|T1FVN1_HELRO
Uncharacterized protein
Search

0.58	Matrix metalloproteinase

0.61	GO:0006508	proteolysis
0.50	GO:0006954	inflammatory response
0.46	GO:0060022	hard palate development
0.41	GO:0030574	collagen catabolic process
0.37	GO:0032879	regulation of localization
0.37	GO:0042060	wound healing
0.37	GO:0016477	cell migration
0.37	GO:0010727	negative regulation of hydrogen peroxide metabolic process
0.37	GO:0048193	Golgi vesicle transport
0.37	GO:0040012	regulation of locomotion

0.70	GO:0004222	metalloendopeptidase activity
0.63	GO:0008270	zinc ion binding
0.36	GO:0005518	collagen binding
0.36	GO:0001047	core promoter binding
0.35	GO:0008201	heparin binding
0.35	GO:0005509	calcium ion binding
0.34	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.34	GO:0004252	serine-type endopeptidase activity
0.34	GO:0043565	sequence-specific DNA binding
0.34	GO:0016504	peptidase activator activity

0.74	GO:0031012	extracellular matrix
0.38	GO:0030008	TRAPP complex
0.37	GO:0005886	plasma membrane
0.36	GO:0005615	extracellular space
0.35	GO:0009986	cell surface
0.35	GO:0031225	anchored component of membrane
0.35	GO:0035579	specific granule membrane
0.34	GO:1903561	extracellular vesicle
0.34	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0005634	nucleus

0.70

GO:0004222

tr|T1FVN2|T1FVN2_HELRO
Uncharacterized protein
Search

WDR47

0.75	WD repeat-containing protein 47 (Fragment)

0.70	GO:0007219	Notch signaling pathway
0.62	GO:0045892	negative regulation of transcription, DNA-templated
0.48	GO:0055085	transmembrane transport
0.46	GO:0007275	multicellular organism development
0.44	GO:0120036	plasma membrane bounded cell projection organization
0.43	GO:0048468	cell development
0.40	GO:0006438	valyl-tRNA aminoacylation
0.39	GO:0106074	aminoacyl-tRNA metabolism involved in translational fidelity
0.39	GO:0006366	transcription by RNA polymerase II
0.38	GO:0000413	protein peptidyl-prolyl isomerization

0.66	GO:0003682	chromatin binding
0.55	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.48	GO:0032559	adenyl ribonucleotide binding
0.47	GO:0008144	drug binding
0.47	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0030507	spectrin binding
0.45	GO:0005516	calmodulin binding
0.43	GO:0008017	microtubule binding
0.40	GO:0004832	valine-tRNA ligase activity
0.39	GO:0002161	aminoacyl-tRNA editing activity

0.47	GO:0005874	microtubule
0.35	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.40	EC:6.1.1.9	GO:0004832
0.40	KEGG:R03665	GO:0004832

tr|T1FVN3|T1FVN3_HELRO
Uncharacterized protein
Search

tr|T1FVN4|T1FVN4_HELRO
Uncharacterized protein
Search

0.35	GO:0048208	COPII vesicle coating
0.35	GO:0032012	regulation of ARF protein signal transduction
0.35	GO:0006334	nucleosome assembly
0.34	GO:0006914	autophagy
0.34	GO:0006508	proteolysis
0.34	GO:0065009	regulation of molecular function
0.33	GO:0015031	protein transport
0.33	GO:0006281	DNA repair
0.33	GO:0006396	RNA processing
0.33	GO:0090305	nucleic acid phosphodiester bond hydrolysis

0.71	GO:0003779	actin binding
0.35	GO:0005086	ARF guanyl-nucleotide exchange factor activity
0.34	GO:0005509	calcium ion binding
0.34	GO:0003677	DNA binding
0.34	GO:0005102	receptor binding
0.33	GO:0004519	endonuclease activity
0.33	GO:0003723	RNA binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding

0.38	GO:0009986	cell surface
0.36	GO:0000785	chromatin
0.34	GO:0044815	DNA packaging complex
0.34	GO:0097458	neuron part
0.34	GO:0005634	nucleus
0.34	GO:0000139	Golgi membrane
0.34	GO:0032993	protein-DNA complex
0.34	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:1904949	ATPase complex

tr|T1FVN5|T1FVN5_HELRO
Uncharacterized protein
Search

0.84	GO:0097010	eukaryotic translation initiation factor 4F complex assembly
0.69	GO:0006413	translational initiation
0.40	GO:0002181	cytoplasmic translation
0.39	GO:0022618	ribonucleoprotein complex assembly
0.36	GO:0007053	spindle assembly involved in male meiosis
0.36	GO:0035186	syncytial blastoderm mitotic cell cycle
0.35	GO:0000001	mitochondrion inheritance
0.34	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening
0.34	GO:0006446	regulation of translational initiation
0.33	GO:0001522	pseudouridine synthesis

0.62	GO:0003743	translation initiation factor activity
0.42	GO:0043024	ribosomal small subunit binding
0.41	GO:0034057	RNA strand-exchange activity
0.41	GO:0033592	RNA strand annealing activity
0.35	GO:0003729	mRNA binding
0.33	GO:0009982	pseudouridine synthase activity
0.33	GO:0004540	ribonuclease activity
0.33	GO:0017111	nucleoside-triphosphatase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding

0.42	GO:0016281	eukaryotic translation initiation factor 4F complex
0.41	GO:0005844	polysome
0.40	GO:0005829	cytosol
0.34	GO:0043025	neuronal cell body
0.34	GO:0030425	dendrite
0.34	GO:0005882	intermediate filament
0.33	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.33

EC:5.4.99.12

GO:0009982

tr|T1FVN6|T1FVN6_HELRO
Uncharacterized protein
Search

tr|T1FVN7|T1FVN7_HELRO
Uncharacterized protein
Search

tr|T1FVN8|T1FVN8_HELRO
Uncharacterized protein
Search

tr|T1FVN9|T1FVN9_HELRO
Uncharacterized protein
Search

0.30

GO:0044425

membrane part

tr|T1FVP0|T1FVP0_HELRO
Uncharacterized protein
Search

tr|T1FVP1|T1FVP1_HELRO
Uncharacterized protein
Search

tr|T1FVP2|T1FVP2_HELRO
Uncharacterized protein
Search

tr|T1FVP3|T1FVP3_HELRO
Uncharacterized protein
Search

0.54	GO:0035556	intracellular signal transduction
0.45	GO:0016477	cell migration
0.43	GO:0048286	lung alveolus development
0.43	GO:0007044	cell-substrate junction assembly
0.41	GO:0008284	positive regulation of cell proliferation
0.40	GO:0005975	carbohydrate metabolic process
0.38	GO:0006508	proteolysis

0.43	GO:0046872	metal ion binding
0.41	GO:0004565	beta-galactosidase activity
0.41	GO:0008061	chitin binding
0.40	GO:0003779	actin binding
0.39	GO:0004252	serine-type endopeptidase activity
0.38	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds

0.49	GO:0005912	adherens junction
0.46	GO:0030055	cell-substrate junction
0.42	GO:0005622	intracellular
0.41	GO:0009341	beta-galactosidase complex
0.40	GO:0005615	extracellular space
0.40	GO:0009986	cell surface
0.37	GO:0043228	non-membrane-bounded organelle
0.30	GO:0016020	membrane

0.41

EC:3.2.1.23

GO:0004565

tr|T1FVP4|T1FVP4_HELRO
Uncharacterized protein
Search

RTF1

0.83	LOW QUALITY PROTEIN: RNA polymerase-associated protein RTF1 homolog

0.78	GO:0006368	transcription elongation from RNA polymerase II promoter
0.71	GO:0016570	histone modification
0.56	GO:0001711	endodermal cell fate commitment
0.55	GO:0051571	positive regulation of histone H3-K4 methylation
0.54	GO:0043009	chordate embryonic development
0.54	GO:0018023	peptidyl-lysine trimethylation
0.53	GO:0019827	stem cell population maintenance
0.52	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter
0.51	GO:0000122	negative regulation of transcription by RNA polymerase II
0.49	GO:0048589	developmental growth

0.53	GO:0003677	DNA binding
0.48	GO:1990269	RNA polymerase II C-terminal domain phosphoserine binding
0.44	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.33	GO:0003723	RNA binding

0.78	GO:0016593	Cdc73/Paf1 complex
0.48	GO:0005730	nucleolus

tr|T1FVP5|T1FVP5_HELRO
Uncharacterized protein
Search

tr|T1FVP6|T1FVP6_HELRO
Uncharacterized protein
Search

tr|T1FVP7|T1FVP7_HELRO
Uncharacterized protein
Search

0.11	N-alpha-acetyltransferase 35, NatC auxiliary subunit (Fragment)

0.42

GO:0006474

N-terminal protein amino acid acetylation

0.51

GO:0016740

transferase activity

0.43	GO:0031417	NatC complex
0.30	GO:0031224	intrinsic component of membrane

0.51

GO:0016740

tr|T1FVP8|T1FVP8_HELRO
Uncharacterized protein
Search

0.41	GO:0032515	negative regulation of phosphoprotein phosphatase activity
0.41	GO:0050808	synapse organization
0.41	GO:0030004	cellular monovalent inorganic cation homeostasis
0.37	GO:0006468	protein phosphorylation

0.42	GO:0004864	protein phosphatase inhibitor activity
0.41	GO:0004633	phosphopantothenoylcysteine decarboxylase activity
0.40	GO:0042802	identical protein binding
0.37	GO:0004672	protein kinase activity
0.36	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.44	GO:0071513	phosphopantothenoylcysteine decarboxylase complex
0.43	GO:1990143	CoA-synthesizing protein complex
0.30	GO:0016020	membrane

0.41	EC:4.1.1.36	GO:0004633
0.41	KEGG:R03269	GO:0004633

tr|T1FVP9|T1FVP9_HELRO
Uncharacterized protein
Search

tr|T1FVQ0|T1FVQ0_HELRO
Uncharacterized protein
Search

0.62	GO:0006468	protein phosphorylation
0.54	GO:1905224	clathrin-coated pit assembly
0.52	GO:0072318	clathrin coat disassembly
0.52	GO:0090160	Golgi to lysosome transport
0.51	GO:0072600	establishment of protein localization to Golgi
0.50	GO:0010977	negative regulation of neuron projection development
0.49	GO:0072659	protein localization to plasma membrane
0.49	GO:0007030	Golgi organization
0.48	GO:0006898	receptor-mediated endocytosis
0.36	GO:0007029	endoplasmic reticulum organization

0.63	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0030332	cyclin binding
0.34	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.34	GO:0051087	chaperone binding

0.48	GO:0005829	cytosol
0.48	GO:0031982	vesicle
0.46	GO:0048471	perinuclear region of cytoplasm
0.45	GO:0005794	Golgi apparatus
0.36	GO:0005925	focal adhesion
0.34	GO:0045202	synapse
0.30	GO:0016020	membrane

0.34

GO:0008138

tr|T1FVQ1|T1FVQ1_HELRO
Uncharacterized protein
Search

0.48	GO:0045571	negative regulation of imaginal disc growth
0.48	GO:0008069	dorsal/ventral axis specification, ovarian follicular epithelium
0.48	GO:0016318	ommatidial rotation
0.47	GO:0001752	compound eye photoreceptor fate commitment
0.46	GO:0007265	Ras protein signal transduction
0.45	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.42	GO:0010628	positive regulation of gene expression
0.35	GO:0000398	mRNA splicing, via spliceosome
0.35	GO:0034063	stress granule assembly
0.35	GO:0090305	nucleic acid phosphodiester bond hydrolysis

0.59	GO:0003723	RNA binding
0.35	GO:0004386	helicase activity
0.35	GO:0004519	endonuclease activity
0.35	GO:0005515	protein binding
0.34	GO:0008186	RNA-dependent ATPase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0003677	DNA binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0008094	DNA-dependent ATPase activity

0.47	GO:0005829	cytosol
0.44	GO:0010494	cytoplasmic stress granule
0.37	GO:0071011	precatalytic spliceosome
0.36	GO:0071013	catalytic step 2 spliceosome
0.34	GO:0005925	focal adhesion
0.34	GO:0005886	plasma membrane

tr|T1FVQ2|T1FVQ2_HELRO
Uncharacterized protein
Search

0.42	Protein disulfide-isomerase

0.69	GO:0045454	cell redox homeostasis
0.43	GO:0018171	peptidyl-cysteine oxidation
0.43	GO:0034976	response to endoplasmic reticulum stress
0.40	GO:0006457	protein folding
0.34	GO:0019953	sexual reproduction
0.33	GO:0002576	platelet degranulation
0.33	GO:0001654	eye development
0.33	GO:0034599	cellular response to oxidative stress
0.32	GO:0006886	intracellular protein transport
0.32	GO:0006468	protein phosphorylation

0.77	GO:0003756	protein disulfide isomerase activity
0.42	GO:0016972	thiol oxidase activity
0.34	GO:0015037	peptide disulfide oxidoreductase activity
0.33	GO:0016757	transferase activity, transferring glycosyl groups
0.33	GO:0017137	Rab GTPase binding
0.32	GO:0015035	protein disulfide oxidoreductase activity
0.32	GO:0004672	protein kinase activity
0.31	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.67	GO:0005783	endoplasmic reticulum
0.46	GO:0043233	organelle lumen
0.44	GO:0044446	intracellular organelle part
0.41	GO:0009986	cell surface
0.39	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0005615	extracellular space
0.33	GO:0031091	platelet alpha granule
0.32	GO:0012506	vesicle membrane
0.32	GO:0098805	whole membrane
0.32	GO:0098588	bounding membrane of organelle

0.77

EC:5.3.4.1

GO:0003756

tr|T1FVQ3|T1FVQ3_HELRO
Uncharacterized protein
Search

0.61	GO:0010941	regulation of cell death
0.60	GO:0016567	protein ubiquitination
0.59	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling
0.52	GO:0007165	signal transduction
0.47	GO:0045087	innate immune response
0.45	GO:0031325	positive regulation of cellular metabolic process
0.44	GO:0045746	negative regulation of Notch signaling pathway
0.43	GO:0050688	regulation of defense response to virus
0.43	GO:0009615	response to virus
0.43	GO:0009617	response to bacterium

0.67	GO:0005164	tumor necrosis factor receptor binding
0.61	GO:0004842	ubiquitin-protein transferase activity
0.58	GO:0008270	zinc ion binding
0.34	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
0.34	GO:0005509	calcium ion binding
0.33	GO:0008234	cysteine-type peptidase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0032561	guanyl ribonucleotide binding
0.33	GO:0003676	nucleic acid binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.34	GO:0005622	intracellular
0.32	GO:0043227	membrane-bounded organelle
0.30	GO:0016020	membrane

0.34	EC:3.2.1.113	GO:0004571
0.61	KEGG:R03876	GO:0004842

tr|T1FVQ4|T1FVQ4_HELRO
Uncharacterized protein
Search

0.50	C-terminal tandem repeated domain in type 4 procollagen

0.47	GO:0030198	extracellular matrix organization
0.46	GO:0043589	skin morphogenesis
0.46	GO:0032964	collagen biosynthetic process
0.46	GO:0034505	tooth mineralization
0.46	GO:0060351	cartilage development involved in endochondral bone morphogenesis
0.45	GO:0071230	cellular response to amino acid stimulus
0.45	GO:0001957	intramembranous ossification
0.45	GO:0070208	protein heterotrimerization
0.45	GO:0060346	bone trabecula formation
0.45	GO:0010718	positive regulation of epithelial to mesenchymal transition

0.72	GO:0005201	extracellular matrix structural constituent
0.46	GO:0048407	platelet-derived growth factor binding
0.44	GO:0002020	protease binding
0.42	GO:0042802	identical protein binding
0.39	GO:0008201	heparin binding
0.36	GO:0004867	serine-type endopeptidase inhibitor activity
0.35	GO:0005509	calcium ion binding
0.34	GO:0042302	structural constituent of cuticle
0.33	GO:0005178	integrin binding
0.33	GO:0030246	carbohydrate binding

0.69	GO:0005581	collagen trimer
0.59	GO:0044420	extracellular matrix component
0.57	GO:0005578	proteinaceous extracellular matrix
0.46	GO:0099081	supramolecular polymer
0.43	GO:0005615	extracellular space
0.35	GO:0005783	endoplasmic reticulum
0.35	GO:0030141	secretory granule
0.34	GO:0031594	neuromuscular junction
0.34	GO:0005794	Golgi apparatus
0.33	GO:0070013	intracellular organelle lumen

0.32

GO:0004553

tr|T1FVQ5|T1FVQ5_HELRO
Uncharacterized protein
Search

0.50	GO:2001141	regulation of RNA biosynthetic process
0.50	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.49	GO:0002121	inter-male aggressive behavior
0.49	GO:0010468	regulation of gene expression
0.49	GO:0007526	larval somatic muscle development
0.48	GO:0008586	imaginal disc-derived wing vein morphogenesis
0.48	GO:0007480	imaginal disc-derived leg morphogenesis
0.48	GO:0045879	negative regulation of smoothened signaling pathway
0.48	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway
0.47	GO:0006325	chromatin organization

0.58	GO:0003682	chromatin binding
0.55	GO:0003677	DNA binding
0.53	GO:0140110	transcription regulator activity
0.52	GO:0008270	zinc ion binding
0.47	GO:0070491	repressing transcription factor binding
0.46	GO:0004407	histone deacetylase activity
0.39	GO:0034979	NAD-dependent protein deacetylase activity
0.35	GO:0008267	poly-glutamine tract binding

0.61	GO:0005634	nucleus
0.48	GO:0005705	polytene chromosome interband
0.39	GO:0043233	organelle lumen
0.38	GO:1902494	catalytic complex
0.33	GO:0005829	cytosol

0.46

GO:0004407

tr|T1FVQ6|T1FVQ6_HELRO
Uncharacterized protein
Search

0.50	GO:2001141	regulation of RNA biosynthetic process
0.50	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.49	GO:0010468	regulation of gene expression
0.49	GO:0002121	inter-male aggressive behavior
0.49	GO:0007526	larval somatic muscle development
0.48	GO:0008586	imaginal disc-derived wing vein morphogenesis
0.48	GO:0045879	negative regulation of smoothened signaling pathway
0.48	GO:0007480	imaginal disc-derived leg morphogenesis
0.48	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway
0.47	GO:0035065	regulation of histone acetylation

0.58	GO:0003682	chromatin binding
0.55	GO:0003677	DNA binding
0.53	GO:0140110	transcription regulator activity
0.52	GO:0008270	zinc ion binding
0.47	GO:0070491	repressing transcription factor binding
0.46	GO:0004407	histone deacetylase activity
0.39	GO:0034979	NAD-dependent protein deacetylase activity
0.35	GO:0008267	poly-glutamine tract binding
0.34	GO:0001784	phosphotyrosine residue binding
0.32	GO:0004871	signal transducer activity

0.61	GO:0005634	nucleus
0.48	GO:0005705	polytene chromosome interband
0.39	GO:0043233	organelle lumen
0.38	GO:1902494	catalytic complex
0.33	GO:0005829	cytosol

0.46

GO:0004407

tr|T1FVQ7|T1FVQ7_HELRO
Uncharacterized protein
Search

tr|T1FVQ8|T1FVQ8_HELRO
Uncharacterized protein
Search

0.43	GO:0007160	cell-matrix adhesion
0.36	GO:0040008	regulation of growth
0.34	GO:0007346	regulation of mitotic cell cycle

0.36	GO:0102567	phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
0.36	GO:0102568	phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
0.35	GO:0004623	phospholipase A2 activity
0.34	GO:0005515	protein binding
0.34	GO:0003735	structural constituent of ribosome

0.41	GO:0009986	cell surface
0.40	GO:0005886	plasma membrane
0.37	GO:0005765	lysosomal membrane
0.36	GO:0070062	extracellular exosome
0.35	GO:0005783	endoplasmic reticulum
0.34	GO:0005634	nucleus
0.34	GO:0005739	mitochondrion
0.30	GO:0044425	membrane part

0.35

EC:3.1.1.4

GO:0004623

tr|T1FVQ9|T1FVQ9_HELRO
Uncharacterized protein
Search

0.56

Coactosin

0.74

GO:0003779

actin binding

0.45

GO:0005622

intracellular

tr|T1FVR0|T1FVR0_HELRO
Uncharacterized protein
Search

0.48	GO:0043983	histone H4-K12 acetylation
0.47	GO:0043982	histone H4-K8 acetylation
0.47	GO:0043981	histone H4-K5 acetylation
0.46	GO:0043966	histone H3 acetylation
0.40	GO:0060395	SMAD protein signal transduction
0.39	GO:0051865	protein autoubiquitination
0.39	GO:1990138	neuron projection extension
0.39	GO:0000209	protein polyubiquitination
0.39	GO:0050769	positive regulation of neurogenesis
0.36	GO:0050790	regulation of catalytic activity

0.54	GO:0046872	metal ion binding
0.38	GO:0061630	ubiquitin protein ligase activity
0.36	GO:0030234	enzyme regulator activity
0.35	GO:0018024	histone-lysine N-methyltransferase activity

0.43	GO:0000123	histone acetyltransferase complex
0.30	GO:0031224	intrinsic component of membrane

0.35

GO:0018024

tr|T1FVR1|T1FVR1_HELRO
Uncharacterized protein
Search

tr|T1FVR2|T1FVR2_HELRO
Uncharacterized protein
Search

0.44	GO:0034968	histone lysine methylation
0.42	GO:0045944	positive regulation of transcription by RNA polymerase II
0.36	GO:0006351	transcription, DNA-templated

0.53	GO:0046872	metal ion binding
0.44	GO:0018024	histone-lysine N-methyltransferase activity
0.42	GO:0044212	transcription regulatory region DNA binding
0.41	GO:0003700	DNA binding transcription factor activity
0.38	GO:0043565	sequence-specific DNA binding

0.42	GO:0005634	nucleus
0.40	GO:0034708	methyltransferase complex
0.38	GO:0043233	organelle lumen
0.36	GO:0044446	intracellular organelle part

0.44

GO:0018024

tr|T1FVR3|T1FVR3_HELRO
Uncharacterized protein
Search

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.51	GO:2000036	regulation of stem cell population maintenance
0.50	GO:0001829	trophectodermal cell differentiation
0.45	GO:0034249	negative regulation of cellular amide metabolic process
0.44	GO:0006401	RNA catabolic process
0.43	GO:0032269	negative regulation of cellular protein metabolic process
0.43	GO:0016071	mRNA metabolic process
0.43	GO:0010558	negative regulation of macromolecule biosynthetic process

0.38	GO:0005246	calcium channel regulator activity
0.37	GO:0004535	poly(A)-specific ribonuclease activity
0.33	GO:0005515	protein binding

0.82	GO:0030015	CCR4-NOT core complex
0.61	GO:0005634	nucleus
0.51	GO:0000932	P-body
0.34	GO:0005829	cytosol

0.37

EC:3.1.13.4

GO:0004535

tr|T1FVR4|T1FVR4_HELRO
Uncharacterized protein
Search

tr|T1FVR5|T1FVR5_HELRO
Uncharacterized protein
Search

tr|T1FVR6|T1FVR6_HELRO
Tetraspanin
Search

0.58	Tetraspanin

0.30

GO:0044425

membrane part

tr|T1FVR7|T1FVR7_HELRO
Uncharacterized protein
Search

tr|T1FVR8|T1FVR8_HELRO
Uncharacterized protein
Search

tr|T1FVR9|T1FVR9_HELRO
Uncharacterized protein
Search

tr|T1FVS0|T1FVS0_HELRO
Uncharacterized protein
Search

tr|T1FVS1|T1FVS1_HELRO
Uncharacterized protein
Search

0.56

GO:0016192

vesicle-mediated transport

0.51

GO:0016788

hydrolase activity, acting on ester bonds

0.41	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.51

GO:0016788

tr|T1FVS2|T1FVS2_HELRO
Uncharacterized protein
Search

0.51	GO:2001141	regulation of RNA biosynthetic process
0.51	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.51	GO:0010468	regulation of gene expression
0.50	GO:0045624	positive regulation of T-helper cell differentiation
0.49	GO:0051574	positive regulation of histone H3-K9 methylation
0.49	GO:0051571	positive regulation of histone H3-K4 methylation
0.46	GO:0051254	positive regulation of RNA metabolic process
0.45	GO:0006338	chromatin remodeling
0.45	GO:0010557	positive regulation of macromolecule biosynthetic process
0.45	GO:0031328	positive regulation of cellular biosynthetic process

0.55	GO:0003677	DNA binding
0.47	GO:0001067	regulatory region nucleic acid binding
0.44	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting
0.42	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.35	GO:0071987	WD40-repeat domain binding
0.34	GO:0003713	transcription coactivator activity
0.32	GO:0008270	zinc ion binding

0.39	GO:0005634	nucleus
0.35	GO:0000785	chromatin
0.34	GO:0070013	intracellular organelle lumen
0.34	GO:0031523	Myb complex
0.33	GO:0005829	cytosol
0.33	GO:0005700	polytene chromosome
0.32	GO:0042025	host cell nucleus
0.30	GO:0016020	membrane

tr|T1FVS3|T1FVS3_HELRO
Uncharacterized protein
Search

0.43	GO:0007018	microtubule-based movement
0.42	GO:0007059	chromosome segregation
0.41	GO:0016567	protein ubiquitination
0.39	GO:0016042	lipid catabolic process
0.39	GO:0051301	cell division
0.38	GO:0060255	regulation of macromolecule metabolic process
0.38	GO:0009889	regulation of biosynthetic process
0.38	GO:0031323	regulation of cellular metabolic process
0.38	GO:0051171	regulation of nitrogen compound metabolic process
0.38	GO:0080090	regulation of primary metabolic process

0.47	GO:0008017	microtubule binding
0.43	GO:0003777	microtubule motor activity
0.41	GO:0004842	ubiquitin-protein transferase activity
0.41	GO:0030554	adenyl nucleotide binding
0.40	GO:0097367	carbohydrate derivative binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0008144	drug binding
0.40	GO:0003723	RNA binding
0.39	GO:0140110	transcription regulator activity
0.36	GO:0004386	helicase activity

0.43	GO:0005876	spindle microtubule
0.43	GO:0000940	condensed chromosome outer kinetochore
0.36	GO:0043231	intracellular membrane-bounded organelle
0.35	GO:0005871	kinesin complex
0.34	GO:0044444	cytoplasmic part
0.34	GO:0012505	endomembrane system
0.34	GO:0005667	transcription factor complex
0.33	GO:0005886	plasma membrane
0.33	GO:0035770	ribonucleoprotein granule
0.33	GO:0070013	intracellular organelle lumen

0.36	EC:3.4	GO:0008233
0.41	KEGG:R03876	GO:0004842

tr|T1FVS4|T1FVS4_HELRO
Uncharacterized protein
Search

0.42	GO:0006030	chitin metabolic process
0.40	GO:0006508	proteolysis
0.40	GO:0005975	carbohydrate metabolic process
0.39	GO:0007016	cytoskeletal anchoring at plasma membrane
0.38	GO:0009057	macromolecule catabolic process
0.37	GO:0007155	cell adhesion
0.36	GO:0006955	immune response
0.36	GO:0006898	receptor-mediated endocytosis
0.35	GO:0044267	cellular protein metabolic process
0.35	GO:0036211	protein modification process

0.41	GO:0008061	chitin binding
0.41	GO:0005509	calcium ion binding
0.40	GO:0008233	peptidase activity
0.40	GO:0030247	polysaccharide binding
0.39	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.38	GO:0004872	receptor activity
0.37	GO:0017171	serine hydrolase activity
0.37	GO:0008270	zinc ion binding
0.35	GO:0016788	hydrolase activity, acting on ester bonds
0.35	GO:0005201	extracellular matrix structural constituent

0.47	GO:0070701	mucus layer
0.38	GO:0016010	dystrophin-associated glycoprotein complex
0.35	GO:0031012	extracellular matrix
0.34	GO:0005618	cell wall
0.34	GO:0016607	nuclear speck
0.33	GO:0016459	myosin complex
0.30	GO:0016021	integral component of membrane

0.40

GO:0008233

tr|T1FVS5|T1FVS5_HELRO
Uncharacterized protein
Search

0.58	GO:0006695	cholesterol biosynthetic process
0.41	GO:0055114	oxidation-reduction process
0.40	GO:0016310	phosphorylation
0.39	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.38	GO:0006703	estrogen biosynthetic process
0.37	GO:0018212	peptidyl-tyrosine modification

0.61	GO:0000253	3-keto sterol reductase activity
0.41	GO:0016301	kinase activity
0.39	GO:0038064	collagen receptor activity
0.37	GO:0004303	estradiol 17-beta-dehydrogenase activity
0.37	GO:0003676	nucleic acid binding
0.35	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.35	GO:0140096	catalytic activity, acting on a protein
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.50	GO:0005783	endoplasmic reticulum
0.36	GO:0005887	integral component of plasma membrane
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0031984	organelle subcompartment

0.61

EC:1.1.1.270

GO:0000253

tr|T1FVS6|T1FVS6_HELRO
Uncharacterized protein
Search

0.63	GO:0006468	protein phosphorylation
0.41	GO:0005978	glycogen biosynthetic process
0.40	GO:0018209	peptidyl-serine modification
0.40	GO:0035556	intracellular signal transduction
0.37	GO:0009789	positive regulation of abscisic acid-activated signaling pathway
0.37	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway
0.36	GO:0009405	pathogenesis
0.36	GO:0009738	abscisic acid-activated signaling pathway
0.35	GO:0007049	cell cycle
0.35	GO:0000226	microtubule cytoskeleton organization

0.63	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0005509	calcium ion binding
0.43	GO:0005516	calmodulin binding
0.37	GO:0000287	magnesium ion binding
0.36	GO:0004143	diacylglycerol kinase activity
0.36	GO:0003951	NAD+ kinase activity
0.35	GO:0004872	receptor activity

0.43	GO:0005964	phosphorylase kinase complex
0.36	GO:0005634	nucleus
0.35	GO:0005829	cytosol
0.35	GO:0031616	spindle pole centrosome
0.35	GO:0032133	chromosome passenger complex
0.34	GO:0051233	spindle midzone
0.34	GO:0099512	supramolecular fiber
0.34	GO:0000779	condensed chromosome, centromeric region
0.34	GO:0005886	plasma membrane
0.33	GO:0031974	membrane-enclosed lumen

0.36	EC:2.7.1.107	GO:0004143
0.36	KEGG:R00104	GO:0003951

tr|T1FVS7|T1FVS7_HELRO
Uncharacterized protein
Search

0.59	GO:0006468	protein phosphorylation
0.41	GO:0005978	glycogen biosynthetic process
0.36	GO:0018210	peptidyl-threonine modification
0.36	GO:0018209	peptidyl-serine modification
0.34	GO:0035556	intracellular signal transduction

0.60	GO:0004672	protein kinase activity
0.52	GO:0032559	adenyl ribonucleotide binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0046872	metal ion binding
0.41	GO:0005516	calmodulin binding

0.43	GO:0005964	phosphorylase kinase complex
0.30	GO:0016020	membrane

tr|T1FVS8|T1FVS8_HELRO
Uncharacterized protein
Search

tr|T1FVS9|T1FVS9_HELRO
Uncharacterized protein
Search

tr|T1FVT0|T1FVT0_HELRO
Uncharacterized protein
Search

0.74	Phosphatidylinositol-4-phosphate 5-kinase type-1 alpha

0.75	GO:0046854	phosphatidylinositol phosphorylation
0.39	GO:0010761	fibroblast migration
0.39	GO:0048041	focal adhesion assembly
0.38	GO:0097178	ruffle assembly
0.38	GO:0090630	activation of GTPase activity
0.38	GO:0072659	protein localization to plasma membrane
0.38	GO:0060326	cell chemotaxis
0.37	GO:0006661	phosphatidylinositol biosynthetic process
0.37	GO:0031532	actin cytoskeleton reorganization

0.82	GO:0016307	phosphatidylinositol phosphate kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0019900	kinase binding

0.38	GO:0032587	ruffle membrane
0.38	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex
0.38	GO:0030027	lamellipodium
0.37	GO:0016607	nuclear speck
0.36	GO:0005829	cytosol
0.35	GO:0005747	mitochondrial respiratory chain complex I
0.30	GO:0016021	integral component of membrane

0.82

GO:0016307

tr|T1FVT1|T1FVT1_HELRO
Tetraspanin
Search

0.25	Tetraspanin

0.43	GO:0014005	microglia development
0.42	GO:0014002	astrocyte development
0.42	GO:0048709	oligodendrocyte differentiation
0.41	GO:0042552	myelination
0.41	GO:0006954	inflammatory response
0.40	GO:0061564	axon development
0.36	GO:0007166	cell surface receptor signaling pathway
0.34	GO:0006631	fatty acid metabolic process
0.32	GO:0055114	oxidation-reduction process

0.35

GO:0003857

3-hydroxyacyl-CoA dehydrogenase activity

0.41	GO:0043209	myelin sheath
0.36	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.35

EC:1.1.1.35

GO:0003857

tr|T1FVT2|T1FVT2_HELRO
Uncharacterized protein
Search

tr|T1FVT3|T1FVT3_HELRO
Uncharacterized protein
Search

tr|T1FVT4|T1FVT4_HELRO
Uncharacterized protein
Search

0.70	GO:0006414	translational elongation
0.34	GO:0030041	actin filament polymerization
0.33	GO:0009617	response to bacterium

0.71	GO:0003746	translation elongation factor activity
0.36	GO:0003924	GTPase activity
0.35	GO:0032550	purine ribonucleoside binding
0.35	GO:0019001	guanyl nucleotide binding
0.34	GO:0003785	actin monomer binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003677	DNA binding

0.83	GO:0005853	eukaryotic translation elongation factor 1 complex
0.34	GO:0045335	phagocytic vesicle
0.33	GO:0005938	cell cortex
0.33	GO:0005615	extracellular space
0.30	GO:0016020	membrane

tr|T1FVT5|T1FVT5_HELRO
Uncharacterized protein
Search

tr|T1FVT6|T1FVT6_HELRO
Uncharacterized protein
Search

tr|T1FVT7|T1FVT7_HELRO
Uncharacterized protein
Search

RHBDF1

0.88	Inactive rhomboid protein 1

0.59	GO:0006508	proteolysis
0.54	GO:0042058	regulation of epidermal growth factor receptor signaling pathway
0.54	GO:0050709	negative regulation of protein secretion
0.51	GO:0061136	regulation of proteasomal protein catabolic process
0.51	GO:0008283	cell proliferation
0.50	GO:0016477	cell migration
0.41	GO:0051604	protein maturation
0.37	GO:0015031	protein transport

0.67	GO:0004252	serine-type endopeptidase activity
0.40	GO:0019838	growth factor binding

0.49	GO:0005789	endoplasmic reticulum membrane
0.49	GO:0000139	Golgi membrane
0.34	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.67

GO:0004252

tr|T1FVT8|T1FVT8_HELRO
Uncharacterized protein
Search

0.81	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.62	GO:0006468	protein phosphorylation
0.48	GO:0032204	regulation of telomere maintenance
0.47	GO:0018209	peptidyl-serine modification
0.46	GO:2001020	regulation of response to DNA damage stimulus
0.45	GO:0046854	phosphatidylinositol phosphorylation
0.40	GO:0006281	DNA repair
0.38	GO:0007274	neuromuscular synaptic transmission
0.38	GO:0048489	synaptic vesicle transport
0.38	GO:0050808	synapse organization

0.69	GO:0004674	protein serine/threonine kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0042162	telomeric DNA binding
0.33	GO:0004930	G-protein coupled receptor activity
0.33	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding
0.33	GO:0003723	RNA binding

0.43	GO:0005654	nucleoplasm
0.37	GO:0045202	synapse
0.36	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0004674

tr|T1FVT9|T1FVT9_HELRO
Uncharacterized protein
Search

0.66

GO:0048190

wing disc dorsal/ventral pattern formation

0.63	GO:0030014	CCR4-NOT complex
0.47	GO:0005829	cytosol
0.42	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

tr|T1FVU0|T1FVU0_HELRO
Uncharacterized protein
Search

0.55	GO:0055085	transmembrane transport
0.44	GO:0015747	urate transport
0.42	GO:0043252	sodium-independent organic anion transport
0.40	GO:0015698	inorganic anion transport
0.38	GO:0046415	urate metabolic process
0.35	GO:0008643	carbohydrate transport
0.35	GO:0042493	response to drug

0.52	GO:0005215	transporter activity
0.37	GO:0030165	PDZ domain binding
0.33	GO:0003677	DNA binding

0.40	GO:0044459	plasma membrane part
0.38	GO:0045177	apical part of cell
0.35	GO:0005840	ribosome
0.35	GO:0009986	cell surface
0.34	GO:0098552	side of membrane
0.30	GO:0016021	integral component of membrane

tr|T1FVU1|T1FVU1_HELRO
Sugar transporter SWEET
Search

0.48	Sugar transporter SWEET

0.69

GO:0008643

carbohydrate transport

0.38	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

tr|T1FVU2|T1FVU2_HELRO
Uncharacterized protein
Search

0.42	GO:0006030	chitin metabolic process
0.41	GO:0016579	protein deubiquitination
0.41	GO:0005975	carbohydrate metabolic process
0.40	GO:0006511	ubiquitin-dependent protein catabolic process
0.40	GO:0016567	protein ubiquitination
0.40	GO:0060255	regulation of macromolecule metabolic process
0.37	GO:0006351	transcription, DNA-templated
0.36	GO:0080090	regulation of primary metabolic process
0.36	GO:0031326	regulation of cellular biosynthetic process
0.36	GO:0051171	regulation of nitrogen compound metabolic process

0.45	GO:0030246	carbohydrate binding
0.44	GO:0050825	ice binding
0.43	GO:0003682	chromatin binding
0.42	GO:0001871	pattern binding
0.42	GO:0008061	chitin binding
0.41	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.41	GO:0004842	ubiquitin-protein transferase activity
0.40	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.40	GO:0005509	calcium ion binding
0.38	GO:0043565	sequence-specific DNA binding

0.48	GO:0005576	extracellular region
0.38	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.41	EC:3.4.19.12	GO:0036459
0.41	KEGG:R03876	GO:0004842

tr|T1FVU3|T1FVU3_HELRO
Uncharacterized protein
Search

tr|T1FVU4|T1FVU4_HELRO
Uncharacterized protein
Search

tr|T1FVU5|T1FVU5_HELRO
Uncharacterized protein
Search

0.43	GO:1903506	regulation of nucleic acid-templated transcription
0.43	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.43	GO:0010468	regulation of gene expression
0.42	GO:0016575	histone deacetylation
0.38	GO:0006413	translational initiation
0.38	GO:0006468	protein phosphorylation
0.38	GO:0065009	regulation of molecular function
0.38	GO:0043044	ATP-dependent chromatin remodeling
0.37	GO:0046907	intracellular transport
0.37	GO:0031338	regulation of vesicle fusion

0.43	GO:0003700	DNA binding transcription factor activity
0.41	GO:0003676	nucleic acid binding
0.38	GO:0098772	molecular function regulator
0.38	GO:0005515	protein binding
0.38	GO:0004672	protein kinase activity
0.38	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0060090	molecular adaptor activity
0.36	GO:0003777	microtubule motor activity

0.42	GO:0005634	nucleus
0.37	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.37	GO:0030173	integral component of Golgi membrane
0.37	GO:0046658	anchored component of plasma membrane
0.37	GO:0030134	COPII-coated ER to Golgi transport vesicle
0.36	GO:0000785	chromatin
0.36	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0031974	membrane-enclosed lumen
0.36	GO:1904949	ATPase complex

0.35

GO:0016887

tr|T1FVU6|T1FVU6_HELRO
Uncharacterized protein
Search

0.68	GO:1901642	nucleoside transmembrane transport
0.40	GO:0016567	protein ubiquitination
0.40	GO:2001141	regulation of RNA biosynthetic process
0.40	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.39	GO:0010468	regulation of gene expression
0.36	GO:0006334	nucleosome assembly
0.36	GO:0032502	developmental process
0.36	GO:0015862	uridine transport
0.36	GO:0051173	positive regulation of nitrogen compound metabolic process
0.35	GO:0010604	positive regulation of macromolecule metabolic process

0.67	GO:0005337	nucleoside transmembrane transporter activity
0.41	GO:0003700	DNA binding transcription factor activity
0.41	GO:0004842	ubiquitin-protein transferase activity
0.36	GO:0008270	zinc ion binding
0.36	GO:0003676	nucleic acid binding
0.36	GO:0016874	ligase activity
0.36	GO:0005515	protein binding
0.35	GO:0003682	chromatin binding
0.35	GO:0016534	cyclin-dependent protein kinase 5 activator activity
0.35	GO:0005509	calcium ion binding

0.52	GO:0005887	integral component of plasma membrane
0.44	GO:0016323	basolateral plasma membrane
0.44	GO:0016324	apical plasma membrane
0.38	GO:0005634	nucleus
0.35	GO:0032991	macromolecular complex
0.35	GO:0000785	chromatin
0.34	GO:0098794	postsynapse
0.34	GO:0097458	neuron part
0.34	GO:0010008	endosome membrane
0.33	GO:0070013	intracellular organelle lumen

0.36	EC:6	GO:0016874
0.41	KEGG:R03876	GO:0004842

tr|T1FVU7|T1FVU7_HELRO
Uncharacterized protein
Search

0.46	GO:0048082	regulation of adult chitin-containing cuticle pigmentation
0.44	GO:0042335	cuticle development
0.44	GO:0043401	steroid hormone mediated signaling pathway
0.44	GO:2001141	regulation of RNA biosynthetic process
0.44	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.43	GO:0010468	regulation of gene expression
0.42	GO:0006468	protein phosphorylation
0.41	GO:0006996	organelle organization
0.40	GO:0007162	negative regulation of cell adhesion
0.40	GO:0048207	vesicle targeting, rough ER to cis-Golgi

0.46	GO:0003677	DNA binding
0.45	GO:0003700	DNA binding transcription factor activity
0.44	GO:0003707	steroid hormone receptor activity
0.42	GO:0004672	protein kinase activity
0.42	GO:0001067	regulatory region nucleic acid binding
0.42	GO:0008270	zinc ion binding
0.41	GO:0046982	protein heterodimerization activity
0.41	GO:0005102	receptor binding
0.41	GO:0043168	anion binding
0.40	GO:0030554	adenyl nucleotide binding

0.51	GO:0005634	nucleus
0.38	GO:0000139	Golgi membrane
0.38	GO:0032991	macromolecular complex
0.38	GO:0000785	chromatin
0.37	GO:0070013	intracellular organelle lumen
0.36	GO:0005886	plasma membrane
0.36	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.37

GO:0004181

tr|T1FVU8|T1FVU8_HELRO
Uncharacterized protein
Search

tr|T1FVU9|T1FVU9_HELRO
Uncharacterized protein
Search

0.39	GO:0036211	protein modification process
0.39	GO:0044267	cellular protein metabolic process
0.39	GO:0050794	regulation of cellular process
0.39	GO:0043051	regulation of pharyngeal pumping
0.38	GO:1901362	organic cyclic compound biosynthetic process
0.38	GO:0018130	heterocycle biosynthetic process
0.38	GO:0019438	aromatic compound biosynthetic process
0.38	GO:0007275	multicellular organism development
0.38	GO:0046662	regulation of oviposition
0.38	GO:0044271	cellular nitrogen compound biosynthetic process

0.41	GO:0050825	ice binding
0.41	GO:0003676	nucleic acid binding
0.39	GO:0016772	transferase activity, transferring phosphorus-containing groups
0.39	GO:0008270	zinc ion binding
0.39	GO:0140096	catalytic activity, acting on a protein
0.39	GO:0017076	purine nucleotide binding
0.39	GO:0097367	carbohydrate derivative binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0008144	drug binding
0.38	GO:0004852	uroporphyrinogen-III synthase activity

0.39	GO:0005634	nucleus
0.37	GO:0009360	DNA polymerase III complex
0.30	GO:0016020	membrane

0.39	EC:2.7	GO:0016772
0.38	KEGG:R03165	GO:0004852

tr|T1FVV0|T1FVV0_HELRO
Uncharacterized protein
Search

0.48	GO:0008104	protein localization
0.44	GO:0016310	phosphorylation

0.54	GO:0019901	protein kinase binding
0.47	GO:0030246	carbohydrate binding
0.45	GO:0016301	kinase activity
0.40	GO:0016787	hydrolase activity

0.55	GO:0005802	trans-Golgi network
0.49	GO:0005829	cytosol
0.43	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

0.40

GO:0016787

tr|T1FVV1|T1FVV1_HELRO
Uncharacterized protein
Search

0.48	GO:1902476	chloride transmembrane transport
0.41	GO:0032259	methylation
0.38	GO:0007162	negative regulation of cell adhesion
0.37	GO:0007165	signal transduction
0.36	GO:0006030	chitin metabolic process
0.36	GO:0009405	pathogenesis
0.36	GO:0007399	nervous system development
0.36	GO:0016570	histone modification
0.35	GO:0018205	peptidyl-lysine modification
0.35	GO:0008213	protein alkylation

0.48	GO:0005247	voltage-gated chloride channel activity
0.41	GO:0008168	methyltransferase activity
0.38	GO:0004871	signal transducer activity
0.36	GO:0008061	chitin binding
0.36	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.36	GO:0005509	calcium ion binding
0.36	GO:0070001	aspartic-type peptidase activity
0.36	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.35	GO:0099600	transmembrane receptor activity
0.35	GO:0030246	carbohydrate binding

0.35	GO:0005886	plasma membrane
0.35	GO:0005576	extracellular region
0.35	GO:0019867	outer membrane
0.30	GO:0016021	integral component of membrane

0.41

GO:0008168

tr|T1FVV2|T1FVV2_HELRO
Uncharacterized protein
Search

0.60	GO:0050790	regulation of catalytic activity
0.54	GO:0007165	signal transduction
0.41	GO:0035307	positive regulation of protein dephosphorylation
0.40	GO:0007098	centrosome cycle
0.39	GO:0046822	regulation of nucleocytoplasmic transport
0.39	GO:0035690	cellular response to drug
0.39	GO:0030155	regulation of cell adhesion
0.39	GO:0045944	positive regulation of transcription by RNA polymerase II
0.39	GO:0000278	mitotic cell cycle
0.38	GO:0044093	positive regulation of molecular function

0.78	GO:0019901	protein kinase binding
0.69	GO:0019208	phosphatase regulator activity
0.41	GO:0071889	14-3-3 protein binding
0.39	GO:0004857	enzyme inhibitor activity
0.33	GO:0046983	protein dimerization activity

0.41	GO:0072357	PTW/PP1 phosphatase complex
0.40	GO:0031672	A band
0.40	GO:0030018	Z disc
0.39	GO:0000776	kinetochore
0.39	GO:0005813	centrosome
0.38	GO:0015629	actin cytoskeleton
0.37	GO:0005829	cytosol
0.35	GO:0070701	mucus layer

tr|T1FVV3|T1FVV3_HELRO
Uncharacterized protein
Search

tr|T1FVV4|T1FVV4_HELRO
Uncharacterized protein
Search

0.47	GO:0035154	terminal cell fate specification, open tracheal system
0.47	GO:0060562	epithelial tube morphogenesis
0.47	GO:0045463	R8 cell development
0.47	GO:0032446	protein modification by small protein conjugation
0.46	GO:0045467	R7 cell development
0.46	GO:0007419	ventral cord development
0.45	GO:0006357	regulation of transcription by RNA polymerase II
0.44	GO:0032793	positive regulation of CREB transcription factor activity
0.44	GO:0048813	dendrite morphogenesis
0.44	GO:0061138	morphogenesis of a branching epithelium

0.45	GO:0008140	cAMP response element binding protein binding
0.44	GO:0031386	protein tag
0.43	GO:0004842	ubiquitin-protein transferase activity
0.43	GO:0003676	nucleic acid binding
0.42	GO:0015616	DNA translocase activity
0.42	GO:0001102	RNA polymerase II activating transcription factor binding
0.40	GO:0016874	ligase activity
0.39	GO:0008061	chitin binding
0.39	GO:0004801	sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity
0.38	GO:0005245	voltage-gated calcium channel activity

0.51	GO:0005634	nucleus
0.43	GO:0070013	intracellular organelle lumen
0.40	GO:0044446	intracellular organelle part
0.38	GO:0005829	cytosol
0.38	GO:0005891	voltage-gated calcium channel complex
0.38	GO:1902494	catalytic complex
0.38	GO:0005694	chromosome
0.37	GO:0005576	extracellular region
0.34	GO:0043234	protein complex

0.40	EC:6	GO:0016874
0.43	KEGG:R03876	GO:0004842

tr|T1FVV5|T1FVV5_HELRO
Uncharacterized protein
Search

0.42	GO:0031018	endocrine pancreas development
0.34	GO:0030245	cellulose catabolic process
0.33	GO:0042981	regulation of apoptotic process

0.62	GO:0008270	zinc ion binding
0.49	GO:0003677	DNA binding
0.34	GO:0030248	cellulose binding
0.33	GO:0042578	phosphoric ester hydrolase activity
0.33	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.33	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

0.33

GO:0042578

tr|T1FVV6|T1FVV6_HELRO
Uncharacterized protein
Search

0.30

GO:0044425

membrane part

tr|T1FVV7|T1FVV7_HELRO
Uncharacterized protein
Search

tr|T1FVV8|T1FVV8_HELRO
Uncharacterized protein
Search

tr|T1FVV9|T1FVV9_HELRO
Uncharacterized protein
Search

0.63	GO:0060271	cilium assembly
0.45	GO:0021508	floor plate formation
0.44	GO:0060972	left/right pattern formation
0.43	GO:0042073	intraciliary transport
0.43	GO:0001947	heart looping
0.43	GO:0001843	neural tube closure
0.42	GO:0007224	smoothened signaling pathway
0.42	GO:0001578	microtubule bundle formation

0.37	GO:0005515	protein binding
0.36	GO:0008080	N-acetyltransferase activity
0.36	GO:0004386	helicase activity
0.32	GO:0003676	nucleic acid binding

0.67	GO:0030992	intraciliary transport particle B
0.62	GO:0005929	cilium
0.62	GO:0005654	nucleoplasm
0.62	GO:0005813	centrosome
0.43	GO:0120038	plasma membrane bounded cell projection part
0.41	GO:0099568	cytoplasmic region
0.30	GO:0031224	intrinsic component of membrane

0.36

GO:0008080

tr|T1FVW0|T1FVW0_HELRO
Uncharacterized protein
Search

tr|T1FVW1|T1FVW1_HELRO
Uncharacterized protein
Search

0.52	GO:0006413	translational initiation
0.38	GO:0002181	cytoplasmic translation
0.37	GO:0006030	chitin metabolic process
0.36	GO:0065009	regulation of molecular function
0.35	GO:0045332	phospholipid translocation
0.35	GO:0006396	RNA processing
0.35	GO:0006796	phosphate-containing compound metabolic process
0.34	GO:0016072	rRNA metabolic process
0.34	GO:0042254	ribosome biogenesis
0.34	GO:0046134	pyrimidine nucleoside biosynthetic process

0.52	GO:0003743	translation initiation factor activity
0.38	GO:0005085	guanyl-nucleotide exchange factor activity
0.37	GO:0008061	chitin binding
0.35	GO:0004012	phospholipid-translocating ATPase activity
0.35	GO:0004849	uridine kinase activity
0.35	GO:0003993	acid phosphatase activity
0.35	GO:0046872	metal ion binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0003700	DNA binding transcription factor activity

0.40	GO:0005851	eukaryotic translation initiation factor 2B complex
0.36	GO:0005576	extracellular region
0.36	GO:0032040	small-subunit processome
0.35	GO:0089701	U2AF
0.30	GO:0016020	membrane

0.35

EC:3.6.3.1

GO:0004012

tr|T1FVW2|T1FVW2_HELRO
Uncharacterized protein
Search

tr|T1FVW3|T1FVW3_HELRO
Uncharacterized protein
Search

tr|T1FVW4|T1FVW4_HELRO
Uncharacterized protein
Search

0.69	Small GTPase superfamily

0.42	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.42	GO:0006891	intra-Golgi vesicle-mediated transport
0.41	GO:0042147	retrograde transport, endosome to Golgi
0.40	GO:0060471	cortical granule exocytosis
0.35	GO:0072600	establishment of protein localization to Golgi
0.34	GO:0015031	protein transport

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0031489	myosin V binding

0.43	GO:0005794	Golgi apparatus
0.39	GO:0060473	cortical granule
0.39	GO:0005829	cytosol
0.36	GO:0031984	organelle subcompartment
0.33	GO:0098588	bounding membrane of organelle
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1FVW5|T1FVW5_HELRO
Uncharacterized protein
Search

0.69	GO:0006357	regulation of transcription by RNA polymerase II
0.46	GO:0048674	collateral sprouting of injured axon
0.45	GO:0031660	regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle
0.45	GO:0016330	second mitotic wave involved in compound eye morphogenesis
0.45	GO:0007464	R3/R4 cell fate commitment
0.45	GO:0046529	imaginal disc fusion, thorax closure
0.44	GO:0009792	embryo development ending in birth or egg hatching
0.44	GO:0048085	adult chitin-containing cuticle pigmentation
0.44	GO:0051124	synaptic growth at neuromuscular junction
0.44	GO:0045475	locomotor rhythm

0.60	GO:0003700	DNA binding transcription factor activity
0.54	GO:0003677	DNA binding
0.43	GO:0070491	repressing transcription factor binding
0.41	GO:0046982	protein heterodimerization activity
0.34	GO:0004672	protein kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.57	GO:0005667	transcription factor complex
0.41	GO:0005634	nucleus
0.39	GO:0015630	microtubule cytoskeleton
0.35	GO:0005737	cytoplasm
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part

tr|T1FVW6|T1FVW6_HELRO
Uncharacterized protein
Search

0.56	ATP-binding cassette sub-family D member

0.71	GO:0006635	fatty acid beta-oxidation
0.64	GO:0000038	very long-chain fatty acid metabolic process
0.55	GO:0055085	transmembrane transport
0.52	GO:0032000	positive regulation of fatty acid beta-oxidation
0.40	GO:0030301	cholesterol transport
0.34	GO:0015909	long-chain fatty acid transport
0.34	GO:0042908	xenobiotic transport
0.33	GO:0015893	drug transport

0.66	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0042803	protein homodimerization activity
0.34	GO:0005324	long-chain fatty acid transporter activity
0.34	GO:0042910	xenobiotic transmembrane transporter activity
0.33	GO:0015238	drug transmembrane transporter activity

0.70	GO:0005777	peroxisome
0.60	GO:0031903	microbody membrane
0.33	GO:0005739	mitochondrion
0.33	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

tr|T1FVW7|T1FVW7_HELRO
Uncharacterized protein
Search

tr|T1FVW8|T1FVW8_HELRO
Palmitoyltransferase
Search

0.21	Palmitoyltransferase

0.79	GO:0019706	protein-cysteine S-palmitoyltransferase activity
0.33	GO:0008270	zinc ion binding
0.32	GO:0016787	hydrolase activity

0.33	GO:0005840	ribosome
0.30	GO:0044425	membrane part

0.79

GO:0019706

tr|T1FVW9|T1FVW9_HELRO
Uncharacterized protein
Search

tr|T1FVX0|T1FVX0_HELRO
Uncharacterized protein
Search

SLC30A6

0.96	Zinc transporter 6-A

0.61	GO:0098655	cation transmembrane transport
0.49	GO:0061088	regulation of sequestering of zinc ion
0.48	GO:0010043	response to zinc ion
0.47	GO:0006829	zinc II ion transport
0.40	GO:0098660	inorganic ion transmembrane transport
0.36	GO:0006895	Golgi to endosome transport

0.61	GO:0008324	cation transmembrane transporter activity
0.40	GO:0015318	inorganic molecular entity transmembrane transporter activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.50	GO:0005794	Golgi apparatus
0.34	GO:0005829	cytosol
0.34	GO:0005739	mitochondrion
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

tr|T1FVX1|T1FVX1_HELRO
Uncharacterized protein
Search

0.69	GO:0018108	peptidyl-tyrosine phosphorylation
0.64	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.59	GO:2001028	positive regulation of endothelial cell chemotaxis
0.57	GO:0050918	positive chemotaxis
0.56	GO:0071526	semaphorin-plexin signaling pathway
0.52	GO:0070495	negative regulation of thrombin-activated receptor signaling pathway
0.52	GO:1905098	negative regulation of guanyl-nucleotide exchange factor activity
0.51	GO:1901299	negative regulation of hydrogen peroxide-mediated programmed cell death
0.51	GO:0001886	endothelial cell morphogenesis
0.50	GO:0051497	negative regulation of stress fiber assembly

0.69	GO:0004713	protein tyrosine kinase activity
0.66	GO:0019199	transmembrane receptor protein kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0008144	drug binding
0.48	GO:0019903	protein phosphatase binding
0.45	GO:0042802	identical protein binding
0.34	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.34	GO:0043274	phospholipase binding

0.50	GO:0009925	basal plasma membrane
0.35	GO:0009986	cell surface
0.34	GO:0060076	excitatory synapse
0.34	GO:0005576	extracellular region
0.34	GO:0036126	sperm flagellum
0.34	GO:0014069	postsynaptic density
0.34	GO:0043025	neuronal cell body
0.34	GO:0030425	dendrite
0.34	GO:0045211	postsynaptic membrane
0.33	GO:0016281	eukaryotic translation initiation factor 4F complex

0.69	EC:2.7.10	GO:0004713
0.34	KEGG:R04545	GO:0046934

tr|T1FVX2|T1FVX2_HELRO
Uncharacterized protein
Search

0.50	GO:0006359	regulation of transcription by RNA polymerase III
0.50	GO:0006383	transcription by RNA polymerase III
0.46	GO:0006364	rRNA processing
0.44	GO:0007018	microtubule-based movement
0.43	GO:0048015	phosphatidylinositol-mediated signaling
0.43	GO:0006270	DNA replication initiation
0.42	GO:0046854	phosphatidylinositol phosphorylation
0.37	GO:0000027	ribosomal large subunit assembly
0.36	GO:0006508	proteolysis
0.36	GO:0045454	cell redox homeostasis

0.51	GO:0001026	TFIIIB-type transcription factor activity
0.44	GO:0003777	microtubule motor activity
0.42	GO:0032555	purine ribonucleotide binding
0.42	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0003677	DNA binding
0.41	GO:0030554	adenyl nucleotide binding
0.41	GO:0008144	drug binding
0.41	GO:0008270	zinc ion binding
0.40	GO:0008017	microtubule binding
0.40	GO:0032550	purine ribonucleoside binding

0.51	GO:0000126	transcription factor TFIIIB complex
0.50	GO:0032040	small-subunit processome
0.39	GO:0030286	dynein complex
0.38	GO:0005794	Golgi apparatus
0.36	GO:0005730	nucleolus
0.30	GO:0016020	membrane

0.35

EC:3.1.3 EC:3.1.3.41

GO:0016791

tr|T1FVX3|T1FVX3_HELRO
Uncharacterized protein
Search

tr|T1FVX4|T1FVX4_HELRO
Uncharacterized protein
Search

0.61	GO:0097156	fasciculation of motor neuron axon
0.58	GO:0022416	chaeta development
0.58	GO:0032418	lysosome localization
0.58	GO:0046622	positive regulation of organ growth
0.56	GO:0048749	compound eye development
0.56	GO:0001578	microtubule bundle formation
0.56	GO:0050807	regulation of synapse organization
0.55	GO:0031396	regulation of protein ubiquitination
0.54	GO:0007420	brain development
0.42	GO:0035973	aggrephagy

0.54	GO:0046872	metal ion binding
0.42	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity
0.40	GO:0005545	1-phosphatidylinositol binding

0.57	GO:0031594	neuromuscular junction
0.56	GO:0048786	presynaptic active zone
0.54	GO:0005764	lysosome
0.42	GO:0097635	extrinsic component of autophagosome membrane
0.42	GO:0034274	Atg12-Atg5-Atg16 complex
0.40	GO:0016605	PML body
0.40	GO:0016234	inclusion body
0.39	GO:0005635	nuclear envelope
0.38	GO:0005730	nucleolus
0.37	GO:0005829	cytosol

0.42

EC:2.4.1.38

GO:0003831

tr|T1FVX5|T1FVX5_HELRO
Uncharacterized protein
Search

0.57	GO:0035973	aggrephagy
0.35	GO:0007275	multicellular organism development
0.34	GO:0005975	carbohydrate metabolic process
0.32	GO:0008213	protein alkylation
0.32	GO:0016310	phosphorylation
0.32	GO:0043414	macromolecule methylation

0.55	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity
0.53	GO:0005545	1-phosphatidylinositol binding
0.53	GO:0046872	metal ion binding
0.37	GO:0004649	poly(ADP-ribose) glycohydrolase activity
0.33	GO:0005515	protein binding
0.32	GO:0016301	kinase activity
0.32	GO:0008168	methyltransferase activity

0.56	GO:0034274	Atg12-Atg5-Atg16 complex
0.55	GO:0097635	extrinsic component of autophagosome membrane
0.54	GO:0016605	PML body
0.53	GO:0016234	inclusion body
0.50	GO:0005635	nuclear envelope
0.49	GO:0005730	nucleolus
0.47	GO:0005829	cytosol
0.41	GO:0005886	plasma membrane
0.37	GO:0043204	perikaryon
0.36	GO:0030424	axon

0.55

EC:2.4.1.38

GO:0003831

tr|T1FVX6|T1FVX6_HELRO
Uncharacterized protein
Search

0.53	GO:0035973	aggrephagy
0.43	GO:0097156	fasciculation of motor neuron axon
0.42	GO:0022416	chaeta development
0.42	GO:0032418	lysosome localization
0.42	GO:0046622	positive regulation of organ growth
0.41	GO:0048749	compound eye development
0.41	GO:0001578	microtubule bundle formation
0.41	GO:0050807	regulation of synapse organization
0.41	GO:0031396	regulation of protein ubiquitination
0.40	GO:0007420	brain development

0.53	GO:0046872	metal ion binding
0.51	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity
0.50	GO:0005545	1-phosphatidylinositol binding
0.36	GO:0016301	kinase activity
0.33	GO:0005515	protein binding

0.53	GO:0034274	Atg12-Atg5-Atg16 complex
0.51	GO:0097635	extrinsic component of autophagosome membrane
0.51	GO:0016605	PML body
0.51	GO:0016234	inclusion body
0.47	GO:0005635	nuclear envelope
0.47	GO:0005730	nucleolus
0.45	GO:0005829	cytosol
0.42	GO:0031594	neuromuscular junction
0.41	GO:0048786	presynaptic active zone
0.40	GO:0005764	lysosome

0.51

EC:2.4.1.38

GO:0003831

tr|T1FVX7|T1FVX7_HELRO
Uncharacterized protein
Search

tr|T1FVX8|T1FVX8_HELRO
Uncharacterized protein
Search

0.36	GO:0036211	protein modification process
0.35	GO:0044267	cellular protein metabolic process
0.35	GO:0016310	phosphorylation
0.34	GO:0099139	cheating during chimeric sorocarp development
0.34	GO:0014706	striated muscle tissue development
0.34	GO:0007165	signal transduction
0.34	GO:0016311	dephosphorylation
0.34	GO:0043327	chemotaxis to cAMP
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.45	GO:0003682	chromatin binding
0.38	GO:0003676	nucleic acid binding
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0008144	drug binding
0.35	GO:0140096	catalytic activity, acting on a protein
0.35	GO:0016301	kinase activity
0.35	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.34	GO:0016791	phosphatase activity
0.34	GO:0017111	nucleoside-triphosphatase activity

0.54	GO:0005634	nucleus
0.34	GO:1905742	Ras guanyl-nucleotide exchange factor complex
0.34	GO:0042641	actomyosin
0.33	GO:0017053	transcriptional repressor complex
0.32	GO:0043233	organelle lumen
0.32	GO:0005737	cytoplasm
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.35	EC:2.7.1	GO:0016773
0.33	KEGG:R02472	GO:0008677

tr|T1FVX9|T1FVX9_HELRO
Uncharacterized protein
Search

0.40	GO:0060255	regulation of macromolecule metabolic process
0.40	GO:0031323	regulation of cellular metabolic process
0.40	GO:0051171	regulation of nitrogen compound metabolic process
0.40	GO:0080090	regulation of primary metabolic process
0.40	GO:0009889	regulation of biosynthetic process
0.39	GO:0048856	anatomical structure development
0.39	GO:0032501	multicellular organismal process
0.38	GO:0001708	cell fate specification
0.37	GO:0050896	response to stimulus
0.37	GO:0040015	negative regulation of multicellular organism growth

0.67	GO:0008093	cytoskeletal adaptor activity
0.65	GO:0070840	dynein complex binding
0.41	GO:0003676	nucleic acid binding
0.40	GO:0046983	protein dimerization activity
0.39	GO:0140110	transcription regulator activity
0.37	GO:0050825	ice binding
0.37	GO:0046872	metal ion binding
0.37	GO:0008140	cAMP response element binding protein binding
0.36	GO:0042578	phosphoric ester hydrolase activity
0.36	GO:0051393	alpha-actinin binding

0.43	GO:0005634	nucleus
0.37	GO:0000785	chromatin
0.36	GO:0044815	DNA packaging complex
0.35	GO:0043025	neuronal cell body
0.35	GO:0032993	protein-DNA complex
0.35	GO:0070013	intracellular organelle lumen
0.35	GO:0009986	cell surface
0.34	GO:0043234	protein complex
0.34	GO:0005886	plasma membrane
0.33	GO:0005737	cytoplasm

0.36

GO:0042578

tr|T1FVY0|T1FVY0_HELRO
Uncharacterized protein
Search

VPS45

0.64	Vacuolar protein sorting-associated protein 45

0.80	GO:0006904	vesicle docking involved in exocytosis
0.35	GO:0006425	glutaminyl-tRNA aminoacylation
0.35	GO:0015031	protein transport
0.34	GO:0007596	blood coagulation
0.33	GO:0046907	intracellular transport
0.33	GO:0034613	cellular protein localization

0.35	GO:0004819	glutamine-tRNA ligase activity
0.35	GO:0005515	protein binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0046872	metal ion binding

0.46	GO:0010008	endosome membrane
0.45	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:6.1.1.18

GO:0004819

tr|T1FVY1|T1FVY1_HELRO
Uncharacterized protein
Search

tr|T1FVY2|T1FVY2_HELRO
Uncharacterized protein
Search

0.54	GO:0031532	actin cytoskeleton reorganization
0.43	GO:0055114	oxidation-reduction process
0.41	GO:0016180	snRNA processing
0.39	GO:0070544	histone H3-K36 demethylation
0.38	GO:0032259	methylation
0.37	GO:0007018	microtubule-based movement
0.36	GO:0016042	lipid catabolic process
0.34	GO:2001141	regulation of RNA biosynthetic process
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression

0.52	GO:0003779	actin binding
0.44	GO:0016491	oxidoreductase activity
0.44	GO:0046872	metal ion binding
0.39	GO:0032452	histone demethylase activity
0.38	GO:0008168	methyltransferase activity
0.37	GO:0003777	microtubule motor activity
0.36	GO:0003723	RNA binding
0.35	GO:0016887	ATPase activity
0.35	GO:0003700	DNA binding transcription factor activity
0.34	GO:0005524	ATP binding

0.49	GO:0005829	cytosol
0.48	GO:0005634	nucleus
0.40	GO:0031974	membrane-enclosed lumen
0.40	GO:0000428	DNA-directed RNA polymerase complex
0.37	GO:0044446	intracellular organelle part
0.37	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.44

GO:0016491

tr|T1FVY3|T1FVY3_HELRO
Uncharacterized protein
Search

0.50	GO:0007094	mitotic spindle assembly checkpoint
0.46	GO:0036211	protein modification process
0.44	GO:0006338	chromatin remodeling
0.44	GO:0044267	cellular protein metabolic process
0.43	GO:0006950	response to stress
0.41	GO:0031122	cytoplasmic microtubule organization
0.41	GO:0006796	phosphate-containing compound metabolic process
0.41	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.41	GO:0007020	microtubule nucleation
0.40	GO:0045454	cell redox homeostasis

0.47	GO:0035312	5'-3' exodeoxyribonuclease activity
0.46	GO:0140096	catalytic activity, acting on a protein
0.43	GO:0032555	purine ribonucleotide binding
0.43	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.42	GO:0030554	adenyl nucleotide binding
0.42	GO:0008144	drug binding
0.42	GO:0016301	kinase activity
0.40	GO:0005509	calcium ion binding
0.40	GO:0003676	nucleic acid binding

0.44	GO:0005634	nucleus
0.43	GO:0020011	apicoplast
0.41	GO:0000930	gamma-tubulin complex
0.39	GO:0005874	microtubule
0.39	GO:0019013	viral nucleocapsid
0.37	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016021	integral component of membrane

0.42

GO:0016773

tr|T1FVY4|T1FVY4_HELRO
Uncharacterized protein
Search

tr|T1FVY5|T1FVY5_HELRO
Uncharacterized protein
Search

0.43	GO:0000272	polysaccharide catabolic process
0.40	GO:0006508	proteolysis
0.39	GO:0035335	peptidyl-tyrosine dephosphorylation
0.38	GO:0006030	chitin metabolic process
0.37	GO:0007016	cytoskeletal anchoring at plasma membrane
0.37	GO:1903963	arachidonate transport
0.37	GO:0032309	icosanoid secretion
0.37	GO:0050896	response to stimulus
0.36	GO:0044255	cellular lipid metabolic process
0.36	GO:0006898	receptor-mediated endocytosis

0.42	GO:0030246	carbohydrate binding
0.41	GO:0016787	hydrolase activity
0.41	GO:0140096	catalytic activity, acting on a protein
0.41	GO:0005509	calcium ion binding
0.40	GO:0008061	chitin binding
0.39	GO:0008270	zinc ion binding
0.38	GO:0001871	pattern binding
0.38	GO:0031177	phosphopantetheine binding
0.37	GO:0005044	scavenger receptor activity
0.35	GO:0032550	purine ribonucleoside binding

0.49	GO:0070701	mucus layer
0.37	GO:0098797	plasma membrane protein complex
0.37	GO:0090665	glycoprotein complex
0.36	GO:0098533	ATPase dependent transmembrane transport complex
0.32	GO:0005622	intracellular

0.41

GO:0016787

tr|T1FVY6|T1FVY6_HELRO
Uncharacterized protein
Search

KLHL10

0.87	Kelch protein 10

0.83	GO:0048808	male genitalia morphogenesis
0.83	GO:0007286	spermatid development
0.82	GO:0008584	male gonad development
0.81	GO:0048873	homeostasis of number of cells within a tissue
0.80	GO:0009566	fertilization
0.69	GO:0000902	cell morphogenesis
0.59	GO:0016567	protein ubiquitination
0.48	GO:0007349	cellularization
0.47	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.34	GO:0055114	oxidation-reduction process

0.57	GO:0004842	ubiquitin-protein transferase activity
0.36	GO:0005515	protein binding
0.34	GO:0016491	oxidoreductase activity

0.66	GO:0031463	Cul3-RING ubiquitin ligase complex
0.48	GO:0005737	cytoplasm

0.34	EC:1	GO:0016491
0.57	KEGG:R03876	GO:0004842

tr|T1FVY7|T1FVY7_HELRO
Uncharacterized protein
Search

0.55	GO:0055085	transmembrane transport
0.39	GO:0015718	monocarboxylic acid transport
0.33	GO:0032392	DNA geometric change
0.32	GO:1901360	organic cyclic compound metabolic process
0.32	GO:0046483	heterocycle metabolic process
0.32	GO:0006725	cellular aromatic compound metabolic process
0.31	GO:0006807	nitrogen compound metabolic process
0.30	GO:0044238	primary metabolic process

0.39	GO:0008028	monocarboxylic acid transmembrane transporter activity
0.33	GO:0004003	ATP-dependent DNA helicase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0003677	DNA binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.32	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|T1FVY8|T1FVY8_HELRO
Uncharacterized protein
Search

tr|T1FVY9|T1FVY9_HELRO
Uncharacterized protein
Search

tr|T1FVZ0|T1FVZ0_HELRO
Uncharacterized protein
Search

ABCC10

0.75	Multidrug resistance-associated protein 7 (Fragment)

0.55	GO:0055085	transmembrane transport
0.39	GO:0015723	bilirubin transport
0.38	GO:0042144	vacuole fusion, non-autophagic
0.37	GO:0010038	response to metal ion
0.37	GO:0006749	glutathione metabolic process
0.36	GO:0045454	cell redox homeostasis
0.34	GO:0042908	xenobiotic transport
0.34	GO:0015893	drug transport
0.34	GO:0099133	ATP hydrolysis coupled anion transmembrane transport
0.32	GO:0015691	cadmium ion transport

0.66	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0015127	bilirubin transmembrane transporter activity
0.35	GO:0042910	xenobiotic transmembrane transporter activity
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.34	GO:0015238	drug transmembrane transporter activity
0.32	GO:0046982	protein heterodimerization activity
0.32	GO:0015086	cadmium ion transmembrane transporter activity

0.41	GO:0005887	integral component of plasma membrane
0.39	GO:0005774	vacuolar membrane
0.38	GO:0000323	lytic vacuole
0.37	GO:0000322	storage vacuole
0.35	GO:0000325	plant-type vacuole
0.33	GO:0005856	cytoskeleton

0.34

GO:0032440

tr|T1FVZ1|T1FVZ1_HELRO
Uncharacterized protein
Search

tr|T1FVZ2|T1FVZ2_HELRO
Uncharacterized protein
Search

0.77	GO:0006816	calcium ion transport
0.66	GO:0048016	inositol phosphate-mediated signaling
0.60	GO:0034220	ion transmembrane transport
0.54	GO:0051283	negative regulation of sequestering of calcium ion
0.53	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.47	GO:0051649	establishment of localization in cell
0.36	GO:0046000	positive regulation of ecdysteroid secretion
0.35	GO:0030536	larval feeding behavior
0.35	GO:0007629	flight behavior
0.35	GO:0035071	salivary gland cell autophagic cell death

0.70	GO:0005216	ion channel activity
0.66	GO:0070679	inositol 1,4,5 trisphosphate binding
0.63	GO:0015085	calcium ion transmembrane transporter activity
0.60	GO:0022834	ligand-gated channel activity
0.52	GO:0004871	signal transducer activity
0.47	GO:0005509	calcium ion binding
0.33	GO:0004252	serine-type endopeptidase activity

0.56	GO:0005783	endoplasmic reticulum
0.41	GO:0005886	plasma membrane
0.35	GO:0044295	axonal growth cone
0.30	GO:0016021	integral component of membrane

0.33

GO:0004252

tr|T1FVZ3|T1FVZ3_HELRO
Uncharacterized protein
Search

0.10	Inositol 1,4,5-trisphosphate receptor (Fragment)

0.85	GO:0048016	inositol phosphate-mediated signaling
0.77	GO:0070588	calcium ion transmembrane transport
0.50	GO:0051283	negative regulation of sequestering of calcium ion
0.50	GO:0060402	calcium ion transport into cytosol
0.47	GO:0050917	sensory perception of umami taste
0.47	GO:0050916	sensory perception of sweet taste
0.46	GO:0050913	sensory perception of bitter taste
0.46	GO:0060291	long-term synaptic potentiation
0.45	GO:0051592	response to calcium ion
0.45	GO:0007613	memory

0.85	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
0.85	GO:0070679	inositol 1,4,5 trisphosphate binding
0.44	GO:0035091	phosphatidylinositol binding
0.42	GO:0005509	calcium ion binding
0.37	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding
0.36	GO:0000822	inositol hexakisphosphate binding
0.35	GO:0005515	protein binding

0.70	GO:0005783	endoplasmic reticulum
0.44	GO:0043235	receptor complex
0.43	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.42	GO:0005730	nucleolus
0.42	GO:0031984	organelle subcompartment
0.41	GO:0005654	nucleoplasm
0.40	GO:0005887	integral component of plasma membrane
0.36	GO:0098588	bounding membrane of organelle
0.36	GO:0005903	brush border
0.36	GO:0043209	myelin sheath

tr|T1FVZ4|T1FVZ4_HELRO
Uncharacterized protein
Search

0.41	WD domain, G-beta repeat protein

0.83	GO:1904668	positive regulation of ubiquitin protein ligase activity
0.45	GO:0031536	positive regulation of exit from mitosis
0.45	GO:0007455	eye-antennal disc morphogenesis
0.44	GO:0008347	glial cell migration
0.44	GO:0031145	anaphase-promoting complex-dependent catabolic process
0.44	GO:0001745	compound eye morphogenesis
0.43	GO:0010001	glial cell differentiation
0.41	GO:0016567	protein ubiquitination
0.37	GO:0010458	exit from mitosis
0.36	GO:0051301	cell division

0.84	GO:0097027	ubiquitin-protein transferase activator activity
0.84	GO:0010997	anaphase-promoting complex binding
0.42	GO:0061630	ubiquitin protein ligase activity
0.34	GO:0004402	histone acetyltransferase activity
0.34	GO:0004721	phosphoprotein phosphatase activity
0.32	GO:0046872	metal ion binding

0.43	GO:0005814	centriole
0.43	GO:0005680	anaphase-promoting complex
0.42	GO:0030424	axon
0.42	GO:0005813	centrosome
0.42	GO:0005819	spindle
0.34	GO:0031965	nuclear membrane
0.34	GO:0005654	nucleoplasm

0.34

GO:0004402

tr|T1FVZ5|T1FVZ5_HELRO
Uncharacterized protein
Search

0.42	GO:0006030	chitin metabolic process
0.41	GO:0009405	pathogenesis
0.41	GO:0007160	cell-matrix adhesion
0.40	GO:0007495	visceral mesoderm-endoderm interaction involved in midgut development
0.39	GO:0003002	regionalization
0.39	GO:0098586	cellular response to virus
0.38	GO:0060429	epithelium development
0.38	GO:0035335	peptidyl-tyrosine dephosphorylation
0.38	GO:0048646	anatomical structure formation involved in morphogenesis
0.38	GO:0010604	positive regulation of macromolecule metabolic process

0.42	GO:0008061	chitin binding
0.41	GO:0005509	calcium ion binding
0.38	GO:0004725	protein tyrosine phosphatase activity
0.38	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.37	GO:0008017	microtubule binding
0.36	GO:1990380	Lys48-specific deubiquitinase activity
0.36	GO:0030248	cellulose binding
0.36	GO:0070628	proteasome binding
0.36	GO:0043565	sequence-specific DNA binding
0.36	GO:0070011	peptidase activity, acting on L-amino acid peptides

0.44	GO:0005576	extracellular region
0.37	GO:0005874	microtubule
0.36	GO:0005634	nucleus
0.36	GO:0005618	cell wall
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.38

GO:0004725

tr|T1FVZ6|T1FVZ6_HELRO
Uncharacterized protein
Search

tr|T1FVZ7|T1FVZ7_HELRO
Uncharacterized protein
Search

DNAJC11

0.87	DnaJ like protein subfamily C member 11

0.73

GO:0042407

cristae formation

0.35

GO:0005515

protein binding

0.79	GO:0001401	mitochondrial sorting and assembly machinery complex
0.72	GO:0061617	MICOS complex
0.41	GO:0070062	extracellular exosome

tr|T1FVZ8|T1FVZ8_HELRO
Uncharacterized protein
Search

0.67	GO:0043666	regulation of phosphoprotein phosphatase activity
0.54	GO:0007165	signal transduction
0.47	GO:0032446	protein modification by small protein conjugation
0.39	GO:2001141	regulation of RNA biosynthetic process
0.39	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.39	GO:0010468	regulation of gene expression
0.39	GO:0008052	sensory organ boundary specification
0.38	GO:0048592	eye morphogenesis
0.38	GO:0008407	chaeta morphogenesis
0.38	GO:0030182	neuron differentiation

0.68	GO:0019888	protein phosphatase regulator activity
0.47	GO:0004842	ubiquitin-protein transferase activity
0.40	GO:0003700	DNA binding transcription factor activity
0.40	GO:0043565	sequence-specific DNA binding
0.38	GO:0004722	protein serine/threonine phosphatase activity
0.37	GO:0046872	metal ion binding
0.37	GO:0043425	bHLH transcription factor binding
0.35	GO:0016874	ligase activity
0.35	GO:0005525	GTP binding
0.35	GO:0004430	1-phosphatidylinositol 4-kinase activity

0.72	GO:0030289	protein phosphatase 4 complex
0.38	GO:0005634	nucleus
0.36	GO:0005700	polytene chromosome
0.35	GO:0030688	preribosome, small subunit precursor
0.35	GO:0030122	AP-2 adaptor complex
0.34	GO:0043233	organelle lumen
0.30	GO:0016021	integral component of membrane

0.35	EC:6	GO:0016874
0.47	KEGG:R03876	GO:0004842

tr|T1FVZ9|T1FVZ9_HELRO
Uncharacterized protein
Search

0.68	GO:0045454	cell redox homeostasis
0.47	GO:0006662	glycerol ether metabolic process
0.38	GO:0055114	oxidation-reduction process
0.36	GO:0000413	protein peptidyl-prolyl isomerization
0.36	GO:0006457	protein folding
0.33	GO:0043043	peptide biosynthetic process
0.33	GO:0010467	gene expression
0.33	GO:0009059	macromolecule biosynthetic process

0.46	GO:0015035	protein disulfide oxidoreductase activity
0.40	GO:0008270	zinc ion binding
0.36	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.34	GO:0003735	structural constituent of ribosome

0.35	GO:0005622	intracellular
0.33	GO:1990904	ribonucleoprotein complex
0.33	GO:0043228	non-membrane-bounded organelle
0.30	GO:0044425	membrane part

0.36

GO:0003755

tr|T1FW00|T1FW00_HELRO
Uncharacterized protein
Search

tr|T1FW01|T1FW01_HELRO
Uncharacterized protein
Search

tr|T1FW02|T1FW02_HELRO
Uncharacterized protein
Search

tr|T1FW03|T1FW03_HELRO
Uncharacterized protein
Search

0.66	GO:0007018	microtubule-based movement
0.43	GO:0030518	intracellular steroid hormone receptor signaling pathway
0.41	GO:0007099	centriole replication
0.41	GO:0045944	positive regulation of transcription by RNA polymerase II
0.39	GO:0016055	Wnt signaling pathway
0.37	GO:0006809	nitric oxide biosynthetic process
0.37	GO:0006351	transcription, DNA-templated
0.37	GO:0060271	cilium assembly
0.36	GO:0007062	sister chromatid cohesion
0.36	GO:0030261	chromosome condensation

0.66	GO:0003777	microtubule motor activity
0.61	GO:0008017	microtubule binding
0.48	GO:0032559	adenyl ribonucleotide binding
0.47	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0008144	drug binding
0.45	GO:0070016	armadillo repeat domain binding
0.43	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.43	GO:0008013	beta-catenin binding
0.43	GO:0008022	protein C-terminus binding
0.43	GO:0001047	core promoter binding

0.43	GO:0015630	microtubule cytoskeleton
0.43	GO:0044430	cytoskeletal part
0.42	GO:0098536	deuterosome
0.41	GO:0000790	nuclear chromatin
0.38	GO:0005829	cytosol
0.36	GO:0005618	cell wall
0.36	GO:0099512	supramolecular fiber
0.35	GO:0005576	extracellular region
0.35	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.37

EC:1.14.13.39

GO:0004517

tr|T1FW04|T1FW04_HELRO
Uncharacterized protein
Search

SMARCAL1

0.85	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A protein 1

0.81	GO:0000733	DNA strand renaturation
0.79	GO:0031297	replication fork processing
0.61	GO:0006281	DNA repair
0.39	GO:0006357	regulation of transcription by RNA polymerase II
0.35	GO:0036292	DNA rewinding
0.35	GO:0030491	heteroduplex formation
0.33	GO:0032508	DNA duplex unwinding
0.33	GO:0006310	DNA recombination
0.32	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.32	GO:0006468	protein phosphorylation

0.83	GO:0036310	annealing helicase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0008094	DNA-dependent ATPase activity
0.35	GO:0004386	helicase activity
0.33	GO:0004683	calmodulin-dependent protein kinase activity
0.33	GO:0008270	zinc ion binding
0.32	GO:0004519	endonuclease activity

0.43	GO:0005662	DNA replication factor A complex
0.42	GO:0035861	site of double-strand break
0.39	GO:0005654	nucleoplasm
0.35	GO:0005705	polytene chromosome interband
0.30	GO:0016020	membrane

0.33

EC:2.7.11.17

GO:0004683

tr|T1FW05|T1FW05_HELRO
Uncharacterized protein
Search

tr|T1FW06|T1FW06_HELRO
Uncharacterized protein
Search

tr|T1FW07|T1FW07_HELRO
Uncharacterized protein
Search

tr|T1FW08|T1FW08_HELRO
Uncharacterized protein
Search

tr|T1FW09|T1FW09_HELRO
Uncharacterized protein
Search

tr|T1FW10|T1FW10_HELRO
Uncharacterized protein
Search

tr|T1FW11|T1FW11_HELRO
Uncharacterized protein
Search

tr|T1FW12|T1FW12_HELRO
Uncharacterized protein
Search

tr|T1FW13|T1FW13_HELRO
Uncharacterized protein
Search

tr|T1FW14|T1FW14_HELRO
Uncharacterized protein
Search

0.61	GO:0016567	protein ubiquitination
0.57	GO:0071379	cellular response to prostaglandin stimulus
0.56	GO:0008584	male gonad development
0.55	GO:0007286	spermatid development
0.55	GO:0009566	fertilization
0.51	GO:0071466	cellular response to xenobiotic stimulus
0.51	GO:0042994	cytoplasmic sequestering of transcription factor
0.49	GO:0002467	germinal center formation
0.49	GO:0043433	negative regulation of DNA binding transcription factor activity
0.48	GO:0050853	B cell receptor signaling pathway

0.56	GO:0004842	ubiquitin-protein transferase activity
0.52	GO:0008134	transcription factor binding
0.41	GO:0030246	carbohydrate binding
0.41	GO:0004252	serine-type endopeptidase activity
0.40	GO:0018024	histone-lysine N-methyltransferase activity
0.35	GO:0016491	oxidoreductase activity

0.68	GO:0031463	Cul3-RING ubiquitin ligase complex
0.39	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.41	EC:3.4.21	GO:0004252
0.56	KEGG:R03876	GO:0004842

tr|T1FW15|T1FW15_HELRO
Uncharacterized protein
Search

tr|T1FW16|T1FW16_HELRO
Uncharacterized protein
Search

0.25	Tetraspanin

0.41	GO:0035188	hatching
0.40	GO:0007166	cell surface receptor signaling pathway
0.39	GO:1901223	negative regulation of NIK/NF-kappaB signaling
0.39	GO:0039532	negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway
0.37	GO:1900746	regulation of vascular endothelial growth factor signaling pathway
0.37	GO:0050931	pigment cell differentiation
0.36	GO:0045807	positive regulation of endocytosis
0.36	GO:0016477	cell migration
0.35	GO:0007155	cell adhesion

0.39	GO:0005887	integral component of plasma membrane
0.36	GO:0012505	endomembrane system
0.36	GO:0005764	lysosome
0.35	GO:0031410	cytoplasmic vesicle

tr|T1FW17|T1FW17_HELRO
Uncharacterized protein
Search

0.38	GO:1903506	regulation of nucleic acid-templated transcription
0.38	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.38	GO:0010468	regulation of gene expression
0.37	GO:0006950	response to stress
0.37	GO:0006260	DNA replication
0.37	GO:0051716	cellular response to stimulus
0.37	GO:0006310	DNA recombination
0.36	GO:0016567	protein ubiquitination
0.35	GO:0006413	translational initiation
0.35	GO:0098754	detoxification

0.44	GO:0003723	RNA binding
0.39	GO:0003700	DNA binding transcription factor activity
0.38	GO:0003697	single-stranded DNA binding
0.37	GO:0046872	metal ion binding
0.36	GO:0004842	ubiquitin-protein transferase activity
0.35	GO:0004601	peroxidase activity
0.34	GO:0016874	ligase activity
0.34	GO:0020037	heme binding
0.34	GO:0017111	nucleoside-triphosphatase activity
0.34	GO:0005267	potassium channel activity

0.38	GO:0019013	viral nucleocapsid
0.37	GO:0030529	intracellular ribonucleoprotein complex
0.37	GO:0005634	nucleus
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.35	EC:1.11.1.7	GO:0004601
0.36	KEGG:R03876	GO:0004842

tr|T1FW18|T1FW18_HELRO
Uncharacterized protein
Search

0.42	N-glycosylase/DNA lyase

0.71	GO:0006284	base-excision repair
0.70	GO:0006289	nucleotide-excision repair
0.35	GO:0034599	cellular response to oxidative stress
0.34	GO:0006364	rRNA processing
0.34	GO:0070987	error-free translesion synthesis
0.34	GO:0007004	telomere maintenance via telomerase
0.33	GO:0051568	histone H3-K4 methylation
0.33	GO:0055085	transmembrane transport
0.32	GO:0006352	DNA-templated transcription, initiation
0.32	GO:1903506	regulation of nucleic acid-templated transcription

0.76	GO:0008534	oxidized purine nucleobase lesion DNA N-glycosylase activity
0.70	GO:0003684	damaged DNA binding
0.49	GO:0016829	lyase activity
0.33	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.33	GO:0004386	helicase activity
0.33	GO:0003700	DNA binding transcription factor activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0003723	RNA binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.34	GO:0031518	CBF3 complex
0.33	GO:0005739	mitochondrion
0.33	GO:0030688	preribosome, small subunit precursor
0.33	GO:0005634	nucleus
0.33	GO:0034708	methyltransferase complex
0.32	GO:0031974	membrane-enclosed lumen
0.30	GO:0016020	membrane

0.76

EC:3.2.2.23

GO:0008534

tr|T1FW19|T1FW19_HELRO
Uncharacterized protein
Search

tr|T1FW20|T1FW20_HELRO
Uncharacterized protein
Search

tr|T1FW21|T1FW21_HELRO
Tubulin alpha chain
Search

0.53	Tubulin alpha chain

0.71	GO:0007017	microtubule-based process
0.71	GO:0007010	cytoskeleton organization
0.41	GO:0007094	mitotic spindle assembly checkpoint

0.76	GO:0005200	structural constituent of cytoskeleton
0.67	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding

0.73	GO:0005874	microtubule
0.46	GO:0005737	cytoplasm
0.36	GO:0044441	ciliary part

tr|T1FW22|T1FW22_HELRO
Uncharacterized protein
Search

0.49	GO:0071364	cellular response to epidermal growth factor stimulus
0.48	GO:1990830	cellular response to leukemia inhibitory factor
0.47	GO:0045944	positive regulation of transcription by RNA polymerase II
0.46	GO:1901838	positive regulation of transcription of nucleolar large rRNA by RNA polymerase I
0.44	GO:0001525	angiogenesis
0.42	GO:0017148	negative regulation of translation
0.41	GO:1903025	regulation of RNA polymerase II regulatory region sequence-specific DNA binding
0.41	GO:0045600	positive regulation of fat cell differentiation
0.40	GO:0045332	phospholipid translocation
0.40	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

0.46	GO:0044547	DNA topoisomerase binding
0.44	GO:0003723	RNA binding
0.44	GO:0008022	protein C-terminus binding
0.44	GO:0042162	telomeric DNA binding
0.42	GO:0042802	identical protein binding
0.40	GO:0004012	phospholipid-translocating ATPase activity
0.39	GO:0003724	RNA helicase activity
0.38	GO:0032559	adenyl ribonucleotide binding
0.38	GO:0004842	ubiquitin-protein transferase activity
0.38	GO:0008144	drug binding

0.49	GO:0005730	nucleolus
0.43	GO:0036464	cytoplasmic ribonucleoprotein granule
0.43	GO:0005654	nucleoplasm
0.42	GO:0005938	cell cortex
0.40	GO:0070062	extracellular exosome
0.39	GO:0032040	small-subunit processome
0.30	GO:0016020	membrane

0.40	EC:3.6.3.1	GO:0004012
0.38	KEGG:R03876	GO:0004842

tr|T1FW23|T1FW23_HELRO
Uncharacterized protein
Search

tr|T1FW24|T1FW24_HELRO
Uncharacterized protein
Search

MCCC2

0.50	Methylcrotonyl-CoA carboxylase carboxyl transferase subunit

0.38	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.37	GO:0006396	RNA processing
0.34	GO:0006552	leucine catabolic process

0.62	GO:0016874	ligase activity
0.40	GO:0032296	double-stranded RNA-specific ribonuclease activity
0.39	GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters
0.37	GO:0047154	methylmalonyl-CoA carboxytransferase activity
0.33	GO:0050897	cobalt ion binding
0.32	GO:0008270	zinc ion binding

0.41	GO:1905202	methylcrotonoyl-CoA carboxylase complex
0.38	GO:0005759	mitochondrial matrix

0.62

GO:0016874

tr|T1FW25|T1FW25_HELRO
Uncharacterized protein
Search

tr|T1FW26|T1FW26_HELRO
Uncharacterized protein
Search

0.74	Hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase, alpha subunit b

0.77

GO:0006635

fatty acid beta-oxidation

0.79	GO:0004300	enoyl-CoA hydratase activity
0.76	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity

0.86

GO:0016507

mitochondrial fatty acid beta-oxidation multienzyme complex

0.79

EC:4.2.1.17

GO:0004300

tr|T1FW27|T1FW27_HELRO
Uncharacterized protein
Search

tr|T1FW28|T1FW28_HELRO
Uncharacterized protein
Search

0.35

GO:0006265

DNA topological change

0.68	GO:0046983	protein dimerization activity
0.38	GO:0070888	E-box binding
0.35	GO:0061505	DNA topoisomerase II activity
0.34	GO:0008094	DNA-dependent ATPase activity
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

tr|T1FW29|T1FW29_HELRO
Uncharacterized protein
Search

tr|T1FW30|T1FW30_HELRO
Uncharacterized protein
Search

0.51	GO:0032259	methylation
0.39	GO:0034721	histone H3-K4 demethylation, trimethyl-H3-K4-specific
0.37	GO:0040028	regulation of vulval development
0.37	GO:0008340	determination of adult lifespan
0.36	GO:0036098	male germ-line stem cell population maintenance
0.35	GO:0043970	histone H3-K9 acetylation
0.35	GO:0030717	karyosome formation
0.35	GO:0007526	larval somatic muscle development
0.35	GO:2000737	negative regulation of stem cell differentiation
0.35	GO:0045475	locomotor rhythm

0.53	GO:0046872	metal ion binding
0.52	GO:0003677	DNA binding
0.51	GO:0008168	methyltransferase activity
0.39	GO:0034647	histone demethylase activity (H3-trimethyl-K4 specific)
0.37	GO:0034648	histone demethylase activity (H3-dimethyl-K4 specific)
0.36	GO:0043992	histone acetyltransferase activity (H3-K9 specific)
0.32	GO:0016491	oxidoreductase activity
0.32	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.34	GO:0000785	chromatin
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:1902494	catalytic complex
0.30	GO:0016020	membrane

0.51

GO:0008168

tr|T1FW31|T1FW31_HELRO
Uncharacterized protein
Search

0.38	GO:1903288	positive regulation of potassium ion import
0.38	GO:0009734	auxin-activated signaling pathway
0.37	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.37	GO:0035220	wing disc development
0.37	GO:0046777	protein autophosphorylation
0.37	GO:0007411	axon guidance
0.35	GO:0060255	regulation of macromolecule metabolic process
0.35	GO:0035023	regulation of Rho protein signal transduction
0.34	GO:0006351	transcription, DNA-templated
0.34	GO:0019219	regulation of nucleobase-containing compound metabolic process

0.76	GO:0045735	nutrient reservoir activity
0.38	GO:0005199	structural constituent of cell wall
0.37	GO:0050825	ice binding
0.35	GO:0004674	protein serine/threonine kinase activity
0.35	GO:0003677	DNA binding
0.35	GO:0003682	chromatin binding
0.35	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.35	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.35

GO:0004674

tr|T1FW32|T1FW32_HELRO
Uncharacterized protein
Search

0.73	GO:0008272	sulfate transport
0.70	GO:0098661	inorganic anion transmembrane transport
0.62	GO:0045852	pH elevation
0.59	GO:0051453	regulation of intracellular pH
0.55	GO:0015701	bicarbonate transport
0.52	GO:0019532	oxalate transport
0.51	GO:0006821	chloride transport
0.49	GO:0070633	transepithelial transport
0.48	GO:0071346	cellular response to interferon-gamma
0.45	GO:0042391	regulation of membrane potential

0.76	GO:0008271	secondary active sulfate transmembrane transporter activity
0.61	GO:0015301	anion:anion antiporter activity
0.53	GO:0015106	bicarbonate transmembrane transporter activity
0.52	GO:0019531	oxalate transmembrane transporter activity
0.51	GO:0015108	chloride transmembrane transporter activity
0.48	GO:0005253	anion channel activity
0.39	GO:0004842	ubiquitin-protein transferase activity
0.39	GO:0051117	ATPase binding
0.38	GO:0004930	G-protein coupled receptor activity
0.37	GO:0005509	calcium ion binding

0.50	GO:0005887	integral component of plasma membrane
0.48	GO:0016324	apical plasma membrane
0.48	GO:0031526	brush border membrane
0.47	GO:0016323	basolateral plasma membrane
0.37	GO:0009986	cell surface
0.35	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0043229	intracellular organelle
0.33	GO:0043228	non-membrane-bounded organelle
0.33	GO:0044444	cytoplasmic part
0.33	GO:0043227	membrane-bounded organelle

0.34	EC:3.4.21	GO:0004252
0.39	KEGG:R03876	GO:0004842

tr|T1FW33|T1FW33_HELRO
Uncharacterized protein
Search

tr|T1FW34|T1FW34_HELRO
Uncharacterized protein
Search

0.74	GO:0043547	positive regulation of GTPase activity
0.61	GO:0007165	signal transduction
0.42	GO:0030336	negative regulation of cell migration
0.36	GO:0060101	negative regulation of phagocytosis, engulfment
0.35	GO:0070587	regulation of cell-cell adhesion involved in gastrulation
0.34	GO:0022409	positive regulation of cell-cell adhesion

0.75	GO:0005096	GTPase activator activity
0.43	GO:0048365	Rac GTPase binding
0.35	GO:0043621	protein self-association
0.34	GO:0042802	identical protein binding

0.35	GO:0005737	cytoplasm
0.34	GO:0005912	adherens junction
0.34	GO:0016342	catenin complex
0.30	GO:0016021	integral component of membrane

tr|T1FW35|T1FW35_HELRO
Uncharacterized protein
Search

tr|T1FW36|T1FW36_HELRO
Uncharacterized protein
Search

0.91	Hippocampus abundant gene transcript 1

0.55	GO:0055085	transmembrane transport
0.33	GO:0008643	carbohydrate transport
0.33	GO:0015992	proton transport

0.56

GO:0005215

transporter activity

0.34	GO:0000139	Golgi membrane
0.30	GO:0016021	integral component of membrane

tr|T1FW37|T1FW37_HELRO
Uncharacterized protein
Search

0.71

GO:0019899

enzyme binding

tr|T1FW38|T1FW38_HELRO
Uncharacterized protein
Search

SYRM

0.63	Probable arginine--tRNA ligase, mitochondrial

0.77	GO:0006420	arginyl-tRNA aminoacylation
0.44	GO:0032543	mitochondrial translation
0.41	GO:0048854	brain morphogenesis
0.32	GO:0055085	transmembrane transport
0.32	GO:0042886	amide transport
0.32	GO:0071702	organic substance transport

0.78	GO:0004814	arginine-tRNA ligase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.32	GO:0015197	peptide transporter activity
0.32	GO:0003723	RNA binding

0.45	GO:0005737	cytoplasm
0.41	GO:0043231	intracellular membrane-bounded organelle
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.78

EC:6.1.1.19

GO:0004814

tr|T1FW39|T1FW39_HELRO
Uncharacterized protein
Search

tr|T1FW40|T1FW40_HELRO
Uncharacterized protein
Search

0.39	GO:0009734	auxin-activated signaling pathway
0.38	GO:0006352	DNA-templated transcription, initiation
0.37	GO:0007162	negative regulation of cell adhesion
0.36	GO:0016567	protein ubiquitination
0.35	GO:2001141	regulation of RNA biosynthetic process
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression
0.35	GO:0035335	peptidyl-tyrosine dephosphorylation
0.34	GO:0006629	lipid metabolic process
0.33	GO:0055114	oxidation-reduction process

0.39	GO:0046982	protein heterodimerization activity
0.37	GO:0004491	methylmalonate-semialdehyde dehydrogenase (acylating) activity
0.37	GO:0004842	ubiquitin-protein transferase activity
0.35	GO:0003677	DNA binding
0.35	GO:0016874	ligase activity
0.35	GO:0004725	protein tyrosine phosphatase activity
0.34	GO:0008270	zinc ion binding

0.41	GO:0046695	SLIK (SAGA-like) complex
0.41	GO:0000124	SAGA complex
0.41	GO:0005669	transcription factor TFIID complex
0.35	GO:0005794	Golgi apparatus
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.37	EC:1.2.1.27	GO:0004491
0.37	KEGG:R03876	GO:0004842

tr|T1FW41|T1FW41_HELRO
Uncharacterized protein
Search

0.53	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway
0.53	GO:0051764	actin crosslink formation
0.53	GO:0034394	protein localization to cell surface
0.53	GO:0051220	cytoplasmic sequestering of protein
0.53	GO:0042993	positive regulation of transcription factor import into nucleus
0.52	GO:0043113	receptor clustering
0.52	GO:2001046	positive regulation of integrin-mediated signaling pathway
0.51	GO:0042177	negative regulation of protein catabolic process
0.51	GO:0043433	negative regulation of DNA binding transcription factor activity
0.51	GO:0016479	negative regulation of transcription by RNA polymerase I

0.76	GO:0051015	actin filament binding
0.56	GO:0034988	Fc-gamma receptor I complex binding
0.52	GO:0048365	Rac GTPase binding
0.51	GO:0017160	Ral GTPase binding
0.51	GO:0015459	potassium channel regulator activity
0.50	GO:0044325	ion channel binding
0.49	GO:0045296	cadherin binding
0.48	GO:0001664	G-protein coupled receptor binding
0.47	GO:0019900	kinase binding
0.47	GO:0008134	transcription factor binding

0.52	GO:0031523	Myb complex
0.50	GO:0031941	filamentous actin
0.47	GO:0005911	cell-cell junction
0.46	GO:0005730	nucleolus
0.44	GO:0005829	cytosol
0.40	GO:0005886	plasma membrane
0.38	GO:0097440	apical dendrite
0.37	GO:0005938	cell cortex
0.37	GO:0043198	dendritic shaft
0.37	GO:0030018	Z disc

tr|T1FW42|T1FW42_HELRO
Uncharacterized protein
Search

tr|T1FW43|T1FW43_HELRO
Uncharacterized protein
Search

0.53	GO:0043044	ATP-dependent chromatin remodeling
0.41	GO:0036211	protein modification process
0.39	GO:0044267	cellular protein metabolic process
0.39	GO:0071824	protein-DNA complex subunit organization
0.39	GO:0006796	phosphate-containing compound metabolic process
0.38	GO:0031323	regulation of cellular metabolic process
0.38	GO:0051171	regulation of nitrogen compound metabolic process
0.38	GO:0060255	regulation of macromolecule metabolic process
0.38	GO:0080090	regulation of primary metabolic process
0.38	GO:0009889	regulation of biosynthetic process

0.45	GO:0046872	metal ion binding
0.44	GO:0030554	adenyl nucleotide binding
0.43	GO:0097367	carbohydrate derivative binding
0.43	GO:0008144	drug binding
0.43	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0140096	catalytic activity, acting on a protein
0.40	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.39	GO:0016301	kinase activity
0.39	GO:0005515	protein binding
0.39	GO:0140110	transcription regulator activity

0.42	GO:0005634	nucleus
0.39	GO:0070013	intracellular organelle lumen
0.39	GO:1902494	catalytic complex
0.38	GO:0044446	intracellular organelle part
0.37	GO:0043234	protein complex
0.36	GO:0020011	apicoplast
0.36	GO:0030018	Z disc
0.36	GO:0005694	chromosome
0.35	GO:0005829	cytosol
0.34	GO:0005886	plasma membrane

0.40

GO:0016773

tr|T1FW44|T1FW44_HELRO
Uncharacterized protein
Search

tr|T1FW45|T1FW45_HELRO
Uncharacterized protein
Search

tr|T1FW46|T1FW46_HELRO
Uncharacterized protein
Search

0.72	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.68	GO:0016567	protein ubiquitination
0.40	GO:0007018	microtubule-based movement

0.71	GO:0061630	ubiquitin protein ligase activity
0.40	GO:0003777	microtubule motor activity
0.40	GO:0008017	microtubule binding
0.38	GO:0032550	purine ribonucleoside binding
0.38	GO:0019001	guanyl nucleotide binding
0.37	GO:0032555	purine ribonucleotide binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0030554	adenyl nucleotide binding
0.35	GO:0008144	drug binding

0.49

GO:0005761

mitochondrial ribosome

tr|T1FW47|T1FW47_HELRO
Uncharacterized protein
Search

tr|T1FW48|T1FW48_HELRO
Uncharacterized protein
Search

tr|T1FW49|T1FW49_HELRO
Uncharacterized protein
Search

0.12	Coiled-coil domain containing 149a

0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding

0.84

GO:0016602

CCAAT-binding factor complex

tr|T1FW50|T1FW50_HELRO
Uncharacterized protein
Search

tr|T1FW51|T1FW51_HELRO
Uncharacterized protein
Search

tr|T1FW52|T1FW52_HELRO
Uncharacterized protein
Search

tr|T1FW53|T1FW53_HELRO
Uncharacterized protein
Search

0.61	GO:0006508	proteolysis
0.50	GO:0007229	integrin-mediated signaling pathway
0.40	GO:0001542	ovulation from ovarian follicle
0.39	GO:0060347	heart trabecula formation
0.39	GO:0006030	chitin metabolic process
0.38	GO:0001822	kidney development

0.70	GO:0004222	metalloendopeptidase activity
0.53	GO:0046872	metal ion binding
0.39	GO:0008061	chitin binding
0.38	GO:0008201	heparin binding

0.39	GO:0005576	extracellular region
0.37	GO:0031410	cytoplasmic vesicle
0.30	GO:0031224	intrinsic component of membrane

0.70

GO:0004222

tr|T1FW54|T1FW54_HELRO
Uncharacterized protein
Search

tr|T1FW55|T1FW55_HELRO
Uncharacterized protein
Search

0.10	Inositol-tetrakisphosphate 1-kinase-like protein

0.57	GO:0032957	inositol trisphosphate metabolic process
0.45	GO:0016310	phosphorylation
0.43	GO:1903506	regulation of nucleic acid-templated transcription
0.43	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.43	GO:0010468	regulation of gene expression
0.41	GO:0032012	regulation of ARF protein signal transduction
0.40	GO:0071310	cellular response to organic substance
0.40	GO:0035154	terminal cell fate specification, open tracheal system
0.40	GO:0045463	R8 cell development
0.40	GO:0009725	response to hormone

0.57	GO:0052726	inositol-1,3,4-trisphosphate 5-kinase activity
0.57	GO:0047325	inositol tetrakisphosphate 1-kinase activity
0.57	GO:0052725	inositol-1,3,4-trisphosphate 6-kinase activity
0.46	GO:0000287	magnesium ion binding
0.43	GO:0030554	adenyl nucleotide binding
0.43	GO:0043168	anion binding
0.43	GO:0097367	carbohydrate derivative binding
0.43	GO:0008144	drug binding
0.43	GO:0003676	nucleic acid binding
0.42	GO:0005515	protein binding

0.45	GO:0005634	nucleus
0.39	GO:0005856	cytoskeleton
0.36	GO:0005952	cAMP-dependent protein kinase complex
0.36	GO:0000138	Golgi trans cisterna
0.36	GO:0034707	chloride channel complex
0.36	GO:0005797	Golgi medial cisterna
0.36	GO:0000324	fungal-type vacuole
0.35	GO:0000151	ubiquitin ligase complex
0.35	GO:1905369	endopeptidase complex
0.35	GO:0043234	protein complex

0.57	EC:2.7.1.159	GO:0052726
0.57	KEGG:R03428	GO:0052726

tr|T1FW56|T1FW56_HELRO
Uncharacterized protein
Search

0.39	GO:2001154	regulation of glycolytic fermentation to ethanol
0.39	GO:0090180	positive regulation of thiamine biosynthetic process
0.38	GO:0043412	macromolecule modification
0.38	GO:0051197	positive regulation of coenzyme metabolic process
0.38	GO:1903580	positive regulation of ATP metabolic process
0.38	GO:0010907	positive regulation of glucose metabolic process
0.38	GO:0043547	positive regulation of GTPase activity
0.37	GO:0016311	dephosphorylation
0.37	GO:0044267	cellular protein metabolic process
0.37	GO:2001141	regulation of RNA biosynthetic process

0.46	GO:0003677	DNA binding
0.38	GO:0043168	anion binding
0.38	GO:0017076	purine nucleotide binding
0.38	GO:0097367	carbohydrate derivative binding
0.38	GO:0003723	RNA binding
0.38	GO:0005096	GTPase activator activity
0.38	GO:0001067	regulatory region nucleic acid binding
0.37	GO:0016791	phosphatase activity
0.37	GO:0009982	pseudouridine synthase activity
0.37	GO:0008144	drug binding

0.42	GO:0005634	nucleus
0.37	GO:1990225	rhoptry neck
0.36	GO:1990130	GATOR1 complex
0.35	GO:0042555	MCM complex
0.35	GO:0005774	vacuolar membrane
0.35	GO:0030659	cytoplasmic vesicle membrane
0.34	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.37	EC:3.1.3 EC:3.1.3.41	GO:0016791
0.35	KEGG:R01055	GO:0004730

tr|T1FW57|T1FW57_HELRO
Uncharacterized protein
Search

0.43	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.42	GO:0016525	negative regulation of angiogenesis
0.41	GO:0030198	extracellular matrix organization
0.41	GO:0072577	endothelial cell apoptotic process
0.40	GO:0007275	multicellular organism development
0.40	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.39	GO:0008283	cell proliferation
0.38	GO:0009888	tissue development
0.37	GO:0061061	muscle structure development
0.37	GO:0071560	cellular response to transforming growth factor beta stimulus

0.66	GO:0005201	extracellular matrix structural constituent
0.40	GO:0005178	integrin binding
0.39	GO:0030246	carbohydrate binding
0.37	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.35	GO:0061783	peptidoglycan muralytic activity
0.35	GO:0003676	nucleic acid binding

0.62	GO:0005581	collagen trimer
0.60	GO:0005604	basement membrane
0.43	GO:0098645	collagen network
0.37	GO:0005783	endoplasmic reticulum
0.36	GO:0005615	extracellular space
0.30	GO:0016020	membrane

0.37

GO:0004553

tr|T1FW58|T1FW58_HELRO
Uncharacterized protein
Search

0.85	GO:0048312	intracellular distribution of mitochondria
0.41	GO:0006413	translational initiation

0.56	GO:0003723	RNA binding
0.35	GO:0042302	structural constituent of cuticle

0.48	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1FW59|T1FW59_HELRO
Uncharacterized protein
Search

LOC106168199

0.76	E3 ubiquitin-protein ligase TRIM56-like isoform X1

0.62	GO:0008270	zinc ion binding
0.62	GO:0016874	ligase activity

0.45

GO:0005622

intracellular

0.62

GO:0016874

tr|T1FW60|T1FW60_HELRO
Uncharacterized protein
Search

tr|T1FW61|T1FW61_HELRO
Uncharacterized protein
Search

0.55	GO:0009734	auxin-activated signaling pathway
0.46	GO:0009908	flower development
0.46	GO:0006355	regulation of transcription, DNA-templated
0.44	GO:0007624	ultradian rhythm
0.43	GO:0006351	transcription, DNA-templated
0.43	GO:0010512	negative regulation of phosphatidylinositol biosynthetic process
0.43	GO:0006897	endocytosis
0.42	GO:0048268	clathrin coat assembly
0.41	GO:0007018	microtubule-based movement
0.40	GO:0043547	positive regulation of GTPase activity

0.44	GO:0003676	nucleic acid binding
0.42	GO:0005515	protein binding
0.42	GO:0005545	1-phosphatidylinositol binding
0.41	GO:0140110	transcription regulator activity
0.41	GO:0003777	microtubule motor activity
0.40	GO:0005096	GTPase activator activity
0.39	GO:0017171	serine hydrolase activity
0.39	GO:0046872	metal ion binding
0.38	GO:0070011	peptidase activity, acting on L-amino acid peptides
0.37	GO:0016740	transferase activity

0.51	GO:0005634	nucleus
0.43	GO:0031410	cytoplasmic vesicle
0.41	GO:0030479	actin cortical patch
0.39	GO:0098805	whole membrane
0.39	GO:0098588	bounding membrane of organelle
0.38	GO:0012505	endomembrane system
0.30	GO:0016021	integral component of membrane

0.37

GO:0016740

tr|T1FW62|T1FW62_HELRO
Uncharacterized protein
Search

0.56	GO:0006886	intracellular protein transport
0.56	GO:0016192	vesicle-mediated transport
0.49	GO:0007034	vacuolar transport
0.49	GO:0016197	endosomal transport
0.37	GO:0006508	proteolysis

0.63	GO:0030276	clathrin binding
0.39	GO:0004222	metalloendopeptidase activity

0.60	GO:0030117	membrane coat
0.50	GO:0012510	trans-Golgi network transport vesicle membrane
0.48	GO:0005768	endosome
0.47	GO:0044431	Golgi apparatus part
0.30	GO:0031224	intrinsic component of membrane

0.39

GO:0004222

tr|T1FW63|T1FW63_HELRO
Uncharacterized protein
Search

0.44	Cleavage and polyadenylation specificity factor subunit

0.33

GO:0006313

transposition, DNA-mediated

0.56	GO:0003723	RNA binding
0.33	GO:0004803	transposase activity

0.36

GO:0005849

mRNA cleavage factor complex

tr|T1FW64|T1FW64_HELRO
Uncharacterized protein
Search

0.10	Kyphoscoliosis peptidase

0.38	GO:0006508	proteolysis
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression
0.33	GO:0061061	muscle structure development

0.52	GO:0046872	metal ion binding
0.38	GO:0008233	peptidase activity
0.33	GO:0005515	protein binding

0.46	GO:0097610	cell surface furrow
0.44	GO:0032155	cell division site part
0.43	GO:0005938	cell cortex
0.36	GO:0005911	cell-cell junction
0.34	GO:0055120	striated muscle dense body
0.30	GO:0031224	intrinsic component of membrane

0.38

GO:0008233

tr|T1FW65|T1FW65_HELRO
Uncharacterized protein
Search

tr|T1FW66|T1FW66_HELRO
Uncharacterized protein
Search

0.47	GO:0012501	programmed cell death
0.45	GO:0016567	protein ubiquitination
0.36	GO:0043409	negative regulation of MAPK cascade
0.36	GO:0035690	cellular response to drug
0.35	GO:0031647	regulation of protein stability
0.35	GO:0048010	vascular endothelial growth factor receptor signaling pathway
0.35	GO:0038084	vascular endothelial growth factor signaling pathway
0.34	GO:0007264	small GTPase mediated signal transduction
0.34	GO:0018108	peptidyl-tyrosine phosphorylation
0.33	GO:0065009	regulation of molecular function

0.48	GO:0016874	ligase activity
0.45	GO:0004842	ubiquitin-protein transferase activity
0.35	GO:0005509	calcium ion binding
0.35	GO:0061659	ubiquitin-like protein ligase activity
0.35	GO:0005021	vascular endothelial growth factor-activated receptor activity
0.34	GO:0005085	guanyl-nucleotide exchange factor activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0003777	microtubule motor activity

0.37	GO:0005737	cytoplasm
0.33	GO:0005887	integral component of plasma membrane

0.48	EC:6	GO:0016874
0.45	KEGG:R03876	GO:0004842

tr|T1FW67|T1FW67_HELRO
Uncharacterized protein
Search

0.74	GO:0016925	protein sumoylation
0.71	GO:0000724	double-strand break repair via homologous recombination
0.65	GO:0016567	protein ubiquitination
0.38	GO:0038169	somatostatin receptor signaling pathway
0.38	GO:0006468	protein phosphorylation
0.37	GO:0030097	hemopoiesis
0.37	GO:0009755	hormone-mediated signaling pathway
0.36	GO:0051726	regulation of cell cycle
0.36	GO:0023051	regulation of signaling
0.35	GO:0006396	RNA processing

0.76	GO:0019789	SUMO transferase activity
0.66	GO:0004842	ubiquitin-protein transferase activity
0.59	GO:0008270	zinc ion binding
0.38	GO:0060089	molecular transducer activity
0.38	GO:0004672	protein kinase activity
0.37	GO:0004563	beta-N-acetylhexosaminidase activity
0.37	GO:0004871	signal transducer activity
0.37	GO:0004000	adenosine deaminase activity
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding

0.74	GO:0030915	Smc5-Smc6 complex
0.35	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.37	EC:3.2.1.52	GO:0004563
0.66	KEGG:R03876	GO:0004842

tr|T1FW68|T1FW68_HELRO
Uncharacterized protein
Search

0.78	GO:0016573	histone acetylation
0.50	GO:0016310	phosphorylation
0.38	GO:0006281	DNA repair
0.36	GO:0016578	histone deubiquitination
0.34	GO:0015074	DNA integration
0.33	GO:2001141	regulation of RNA biosynthetic process

0.52	GO:0016301	kinase activity
0.35	GO:0003712	transcription cofactor activity
0.33	GO:0003676	nucleic acid binding

0.76	GO:0000123	histone acetyltransferase complex
0.36	GO:0000812	Swr1 complex
0.35	GO:0090575	RNA polymerase II transcription factor complex
0.35	GO:0016591	DNA-directed RNA polymerase II, holoenzyme
0.35	GO:0005794	Golgi apparatus

tr|T1FW69|T1FW69_HELRO
Uncharacterized protein
Search

HDAC2

0.51	Histone deacetylase

0.80	GO:0016575	histone deacetylation
0.53	GO:0006351	transcription, DNA-templated
0.53	GO:2001141	regulation of RNA biosynthetic process
0.53	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.52	GO:0010468	regulation of gene expression
0.48	GO:0010870	positive regulation of receptor biosynthetic process
0.45	GO:0042127	regulation of cell proliferation
0.45	GO:0045862	positive regulation of proteolysis
0.43	GO:0051254	positive regulation of RNA metabolic process
0.43	GO:0051253	negative regulation of RNA metabolic process

0.81	GO:0004407	histone deacetylase activity
0.71	GO:0034979	NAD-dependent protein deacetylase activity
0.53	GO:0046872	metal ion binding
0.48	GO:0051059	NF-kappaB binding
0.47	GO:0001103	RNA polymerase II repressing transcription factor binding
0.46	GO:0042826	histone deacetylase binding
0.40	GO:0043565	sequence-specific DNA binding
0.36	GO:0003714	transcription corepressor activity
0.35	GO:0035851	Krueppel-associated box domain binding
0.35	GO:0001226	RNA polymerase II transcription corepressor binding

0.56	GO:0005634	nucleus
0.46	GO:0017053	transcriptional repressor complex
0.45	GO:0034708	methyltransferase complex
0.43	GO:0000785	chromatin
0.42	GO:0070013	intracellular organelle lumen
0.42	GO:1904949	ATPase complex
0.40	GO:0043234	protein complex
0.36	GO:0005705	polytene chromosome interband
0.36	GO:0005737	cytoplasm
0.34	GO:0005657	replication fork

0.81

GO:0004407

tr|T1FW70|T1FW70_HELRO
Uncharacterized protein
Search

0.53	GO:0006468	protein phosphorylation
0.42	GO:0045087	innate immune response
0.42	GO:0007165	signal transduction
0.38	GO:0035159	regulation of tube length, open tracheal system
0.37	GO:0008045	motor neuron axon guidance
0.36	GO:0051336	regulation of hydrolase activity
0.36	GO:0090548	response to nitrate starvation
0.36	GO:1901333	positive regulation of lateral root development
0.36	GO:1902025	nitrate import
0.36	GO:0003002	regionalization

0.54	GO:0004672	protein kinase activity
0.47	GO:0032559	adenyl ribonucleotide binding
0.47	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0008144	drug binding
0.36	GO:0030234	enzyme regulator activity
0.35	GO:0005515	protein binding
0.35	GO:0004826	phenylalanine-tRNA ligase activity
0.35	GO:0017046	peptide hormone binding
0.34	GO:0001653	peptide receptor activity
0.34	GO:0044877	macromolecular complex binding

0.36	GO:0005886	plasma membrane
0.35	GO:0000164	protein phosphatase type 1 complex
0.33	GO:0005968	Rab-protein geranylgeranyltransferase complex
0.33	GO:0005615	extracellular space
0.33	GO:0005929	cilium
0.30	GO:0016021	integral component of membrane

0.35

EC:6.1.1.20

GO:0004826

tr|T1FW71|T1FW71_HELRO
Uncharacterized protein
Search

0.43	GO:0007409	axonogenesis
0.43	GO:1903288	positive regulation of potassium ion import
0.42	GO:0060429	epithelium development
0.42	GO:0043412	macromolecule modification
0.41	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.41	GO:2001141	regulation of RNA biosynthetic process
0.40	GO:0060250	germ-line stem-cell niche homeostasis
0.40	GO:0097485	neuron projection guidance
0.40	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.40	GO:0044267	cellular protein metabolic process

0.45	GO:0042393	histone binding
0.42	GO:0097367	carbohydrate derivative binding
0.42	GO:0003677	DNA binding
0.42	GO:0017076	purine nucleotide binding
0.42	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0003713	transcription coactivator activity
0.41	GO:0004672	protein kinase activity
0.41	GO:0045735	nutrient reservoir activity
0.40	GO:0008144	drug binding
0.40	GO:0046872	metal ion binding

0.47	GO:0005634	nucleus
0.39	GO:0000331	contractile vacuole
0.39	GO:0031143	pseudopodium
0.38	GO:0044446	intracellular organelle part
0.38	GO:0043235	receptor complex
0.38	GO:0045335	phagocytic vesicle
0.38	GO:0005667	transcription factor complex
0.37	GO:0120114	Sm-like protein family complex
0.37	GO:0032153	cell division site
0.36	GO:0098805	whole membrane

tr|T1FW72|T1FW72_HELRO
Uncharacterized protein
Search

tr|T1FW73|T1FW73_HELRO
Uncharacterized protein
Search

tr|T1FW74|T1FW74_HELRO
Uncharacterized protein
Search

0.66	Misshapen (inferred by orthology to a D. melanogaster protein)

0.61	GO:0006468	protein phosphorylation
0.51	GO:0000185	activation of MAPKKK activity
0.43	GO:0048812	neuron projection morphogenesis
0.43	GO:0035556	intracellular signal transduction
0.42	GO:0032228	regulation of synaptic transmission, GABAergic
0.42	GO:0002119	nematode larval development
0.41	GO:0010171	body morphogenesis
0.41	GO:0061564	axon development
0.41	GO:0048667	cell morphogenesis involved in neuron differentiation
0.40	GO:0005975	carbohydrate metabolic process

0.61	GO:0004672	protein kinase activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0005057	signal transducer activity, downstream of receptor
0.43	GO:0030246	carbohydrate binding
0.42	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.36	GO:0005622	intracellular
0.32	GO:0071944	cell periphery
0.30	GO:0016021	integral component of membrane

0.42

GO:0004553

tr|T1FW75|T1FW75_HELRO
Uncharacterized protein
Search

tr|T1FW76|T1FW76_HELRO
Uncharacterized protein
Search

VHL

0.78	von Hippel-Lindau tumor suppressor

0.67	GO:0039022	pronephric duct development
0.65	GO:0043576	regulation of respiratory gaseous exchange
0.64	GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway
0.63	GO:0030218	erythrocyte differentiation
0.61	GO:0045765	regulation of angiogenesis
0.61	GO:0001525	angiogenesis
0.41	GO:0016567	protein ubiquitination

0.42

GO:0061630

ubiquitin protein ligase activity

0.46	GO:0030891	VCB complex
0.38	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|T1FW77|T1FW77_HELRO
Uncharacterized protein
Search

tr|T1FW78|T1FW78_HELRO
Uncharacterized protein
Search

0.76	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.48	GO:0035271	ring gland development
0.48	GO:0001748	optic lobe placode development
0.47	GO:0002121	inter-male aggressive behavior
0.47	GO:0014019	neuroblast development
0.47	GO:0007362	terminal region determination

0.76	GO:0003707	steroid hormone receptor activity
0.64	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.37	GO:0001012	RNA polymerase II regulatory region DNA binding
0.36	GO:0003690	double-stranded DNA binding
0.34	GO:0004824	lysine-tRNA ligase activity
0.33	GO:0004518	nuclease activity
0.33	GO:0005515	protein binding
0.32	GO:0030554	adenyl nucleotide binding

0.61	GO:0005634	nucleus
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:6.1.1.6

GO:0004824

tr|T1FW79|T1FW79_HELRO
Uncharacterized protein
Search

tr|T1FW80|T1FW80_HELRO
Uncharacterized protein
Search

tr|T1FW81|T1FW81_HELRO
Uncharacterized protein
Search

tr|T1FW82|T1FW82_HELRO
Protein tweety homolog
Search

tr|T1FW83|T1FW83_HELRO
Uncharacterized protein
Search

tr|T1FW84|T1FW84_HELRO
Uncharacterized protein
Search

0.73	GO:0006289	nucleotide-excision repair
0.39	GO:0010224	response to UV-B
0.39	GO:0031573	intra-S DNA damage checkpoint
0.39	GO:0070914	UV-damage excision repair
0.37	GO:1901990	regulation of mitotic cell cycle phase transition
0.36	GO:0051276	chromosome organization
0.36	GO:0048478	replication fork protection
0.35	GO:0006298	mismatch repair
0.35	GO:0055114	oxidation-reduction process
0.34	GO:0042981	regulation of apoptotic process

0.73	GO:0003684	damaged DNA binding
0.37	GO:0003697	single-stranded DNA binding
0.35	GO:0016491	oxidoreductase activity
0.34	GO:0016758	transferase activity, transferring hexosyl groups
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005634	nucleus
0.37	GO:1990391	DNA repair complex
0.36	GO:0031974	membrane-enclosed lumen
0.35	GO:0005739	mitochondrion
0.35	GO:0043234	protein complex
0.35	GO:0043232	intracellular non-membrane-bounded organelle
0.34	GO:0044446	intracellular organelle part
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.35

GO:0016491

tr|T1FW85|T1FW85_HELRO
Uncharacterized protein
Search

tr|T1FW86|T1FW86_HELRO
Uncharacterized protein
Search

0.35	GO:0043547	positive regulation of GTPase activity
0.35	GO:0006352	DNA-templated transcription, initiation
0.35	GO:0006030	chitin metabolic process
0.34	GO:0016042	lipid catabolic process
0.33	GO:0007165	signal transduction

0.50	GO:0003676	nucleic acid binding
0.35	GO:0005096	GTPase activator activity
0.34	GO:0046872	metal ion binding
0.34	GO:0008061	chitin binding
0.34	GO:0004004	ATP-dependent RNA helicase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.34	GO:0005576	extracellular region
0.34	GO:0019867	outer membrane
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

tr|T1FW87|T1FW87_HELRO
Uncharacterized protein
Search

0.35	GO:0035023	regulation of Rho protein signal transduction
0.34	GO:0065009	regulation of molecular function
0.33	GO:0006886	intracellular protein transport
0.33	GO:0035556	intracellular signal transduction
0.33	GO:0006811	ion transport
0.32	GO:0055085	transmembrane transport
0.32	GO:0055114	oxidation-reduction process

0.76	GO:0004075	biotin carboxylase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0046872	metal ion binding
0.48	GO:0004485	methylcrotonoyl-CoA carboxylase activity
0.36	GO:0017016	Ras GTPase binding
0.35	GO:0005085	guanyl-nucleotide exchange factor activity
0.34	GO:0008083	growth factor activity
0.34	GO:0005230	extracellular ligand-gated ion channel activity

0.42	GO:1905202	methylcrotonoyl-CoA carboxylase complex
0.39	GO:0005759	mitochondrial matrix
0.37	GO:0005765	lysosomal membrane
0.35	GO:0031966	mitochondrial membrane
0.35	GO:0019866	organelle inner membrane
0.33	GO:0005576	extracellular region
0.33	GO:0005634	nucleus
0.32	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

0.76	EC:6.3.4.14	GO:0004075
0.48	KEGG:R04138	GO:0004485

tr|T1FW88|T1FW88_HELRO
Uncharacterized protein
Search

0.52	GO:0006697	ecdysone biosynthetic process
0.50	GO:0016233	telomere capping
0.49	GO:0006357	regulation of transcription by RNA polymerase II
0.47	GO:0007010	cytoskeleton organization
0.46	GO:0022604	regulation of cell morphogenesis

0.63	GO:0008270	zinc ion binding
0.47	GO:0003682	chromatin binding
0.44	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.38	GO:0003677	DNA binding
0.37	GO:0005515	protein binding

0.52	GO:0035012	polytene chromosome, telomeric region
0.51	GO:0005705	polytene chromosome interband
0.50	GO:0000791	euchromatin
0.49	GO:0000792	heterochromatin
0.45	GO:0005634	nucleus
0.42	GO:0031974	membrane-enclosed lumen
0.41	GO:0043234	protein complex
0.36	GO:0005737	cytoplasm

tr|T1FW89|T1FW89_HELRO
Uncharacterized protein
Search

0.42	GO:2001141	regulation of RNA biosynthetic process
0.42	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.41	GO:0010468	regulation of gene expression
0.39	GO:0060903	positive regulation of meiosis I
0.38	GO:0045332	phospholipid translocation
0.38	GO:0006997	nucleus organization
0.38	GO:0043631	RNA polyadenylation
0.38	GO:0009792	embryo development ending in birth or egg hatching
0.38	GO:0051302	regulation of cell division
0.37	GO:0009190	cyclic nucleotide biosynthetic process

0.49	GO:0016779	nucleotidyltransferase activity
0.44	GO:0140110	transcription regulator activity
0.39	GO:0003723	RNA binding
0.38	GO:0004012	phospholipid-translocating ATPase activity
0.37	GO:0016849	phosphorus-oxygen lyase activity
0.37	GO:0030554	adenyl nucleotide binding
0.37	GO:0097367	carbohydrate derivative binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0004386	helicase activity

0.40	GO:0031379	RNA-directed RNA polymerase complex
0.39	GO:0043186	P granule
0.37	GO:0005634	nucleus
0.36	GO:0005881	cytoplasmic microtubule
0.36	GO:0043234	protein complex
0.35	GO:0032580	Golgi cisterna membrane
0.35	GO:0005815	microtubule organizing center
0.35	GO:1990225	rhoptry neck
0.34	GO:0070013	intracellular organelle lumen
0.34	GO:0031248	protein acetyltransferase complex

0.49

GO:0016779

tr|T1FW90|T1FW90_HELRO
Poly [ADP-ribose] polymerase
Search

0.10	Poly [ADP-ribose] polymerase

0.45	GO:0006915	apoptotic process
0.41	GO:0006508	proteolysis

0.82	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.45	GO:0004197	cysteine-type endopeptidase activity
0.34	GO:0003676	nucleic acid binding
0.33	GO:0046872	metal ion binding

0.82

EC:2.4.2.30

GO:0003950

tr|T1FW91|T1FW91_HELRO
Uncharacterized protein
Search

0.74	GO:0007018	microtubule-based movement
0.72	GO:0001539	cilium or flagellum-dependent cell motility
0.45	GO:0060271	cilium assembly
0.38	GO:0061371	determination of heart left/right asymmetry
0.34	GO:0000413	protein peptidyl-prolyl isomerization

0.75	GO:0003777	microtubule motor activity
0.61	GO:0016887	ATPase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0045503	dynein light chain binding
0.48	GO:0051959	dynein light intermediate chain binding
0.48	GO:0045505	dynein intermediate chain binding
0.34	GO:0003755	peptidyl-prolyl cis-trans isomerase activity

0.84	GO:0005858	axonemal dynein complex
0.34	GO:0031514	motile cilium
0.30	GO:0031224	intrinsic component of membrane

0.61

GO:0016887

tr|T1FW92|T1FW92_HELRO
Uncharacterized protein
Search

tr|T1FW93|T1FW93_HELRO
Uncharacterized protein
Search

tr|T1FW94|T1FW94_HELRO
Uncharacterized protein
Search

0.11	2-(3-amino-3-carboxypropyl)histidine synthase subunit 2

0.83	GO:0017182	peptidyl-diphthamide metabolic process
0.82	GO:1900247	regulation of cytoplasmic translational elongation
0.49	GO:0044249	cellular biosynthetic process

0.50

GO:0016740

transferase activity

0.44	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.50

GO:0016740

tr|T1FW95|T1FW95_HELRO
Uncharacterized protein
Search

tr|T1FW96|T1FW96_HELRO
Uncharacterized protein
Search

tr|T1FW97|T1FW97_HELRO
Uncharacterized protein
Search

0.43	GO:0006357	regulation of transcription by RNA polymerase II
0.42	GO:0048522	positive regulation of cellular process
0.42	GO:0007624	ultradian rhythm
0.42	GO:0010512	negative regulation of phosphatidylinositol biosynthetic process
0.41	GO:0060237	regulation of fungal-type cell wall organization
0.41	GO:0007118	budding cell apical bud growth
0.41	GO:0010557	positive regulation of macromolecule biosynthetic process
0.41	GO:0010628	positive regulation of gene expression
0.41	GO:0000920	cell separation after cytokinesis
0.41	GO:0030950	establishment or maintenance of actin cytoskeleton polarity

0.42	GO:0000989	transcription factor activity, transcription factor binding
0.41	GO:0004674	protein serine/threonine kinase activity
0.41	GO:0004423	iduronate-2-sulfatase activity
0.41	GO:0005515	protein binding
0.41	GO:0046872	metal ion binding
0.40	GO:0008420	CTD phosphatase activity
0.39	GO:0003676	nucleic acid binding
0.39	GO:0005267	potassium channel activity
0.39	GO:0005096	GTPase activator activity
0.38	GO:0043168	anion binding

0.43	GO:0005634	nucleus
0.43	GO:0036464	cytoplasmic ribonucleoprotein granule
0.42	GO:0005938	cell cortex
0.42	GO:0000428	DNA-directed RNA polymerase complex
0.41	GO:0000131	incipient cellular bud site
0.41	GO:0005934	cellular bud tip
0.40	GO:0043332	mating projection tip
0.40	GO:0005935	cellular bud neck
0.40	GO:0044446	intracellular organelle part
0.40	GO:0031251	PAN complex

0.41

GO:0004674

tr|T1FW98|T1FW98_HELRO
Uncharacterized protein
Search

0.37	Mediator of RNA polymerase II transcription subunit 7

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.58	GO:0006351	transcription, DNA-templated
0.51	GO:0019827	stem cell population maintenance
0.36	GO:0016567	protein ubiquitination

0.79	GO:0001104	RNA polymerase II transcription cofactor activity
0.44	GO:0003713	transcription coactivator activity
0.37	GO:0061630	ubiquitin protein ligase activity
0.34	GO:0005515	protein binding

0.77	GO:0016592	mediator complex
0.49	GO:0016604	nuclear body
0.48	GO:0005667	transcription factor complex
0.38	GO:1990234	transferase complex
0.30	GO:0031224	intrinsic component of membrane

tr|T1FW99|T1FW99_HELRO
Uncharacterized protein
Search

0.43	GO:0007155	cell adhesion
0.40	GO:0035556	intracellular signal transduction
0.39	GO:0005975	carbohydrate metabolic process
0.39	GO:0022900	electron transport chain

0.41	GO:0003676	nucleic acid binding
0.39	GO:0009055	electron transfer activity

0.35	GO:0005622	intracellular
0.30	GO:0044425	membrane part

tr|T1FWA0|T1FWA0_HELRO
Uncharacterized protein
Search

tr|T1FWA1|T1FWA1_HELRO
Uncharacterized protein
Search

tr|T1FWA2|T1FWA2_HELRO
Uncharacterized protein
Search

ADAT2

0.44	tRNA-specific adenosine deaminase 2

0.61	GO:0002100	tRNA wobble adenosine to inosine editing
0.36	GO:0007049	cell cycle
0.35	GO:0006468	protein phosphorylation
0.33	GO:0032259	methylation

0.62	GO:0008251	tRNA-specific adenosine deaminase activity
0.60	GO:0008270	zinc ion binding
0.36	GO:0016874	ligase activity
0.35	GO:0004672	protein kinase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0003908	methylated-DNA-[protein]-cysteine S-methyltransferase activity
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005515	protein binding

0.49	GO:0052718	tRNA-specific adenosine-34 deaminase complex
0.33	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

0.62

EC:3.5.4

GO:0008251

tr|T1FWA3|T1FWA3_HELRO
Uncharacterized protein
Search

0.38	UDP-N-acetylglucosamine transporter

0.69	GO:0008643	carbohydrate transport
0.63	GO:1902600	hydrogen ion transmembrane transport
0.49	GO:0090481	pyrimidine nucleotide-sugar transmembrane transport
0.43	GO:0098656	anion transmembrane transport
0.43	GO:0015711	organic anion transport
0.32	GO:0055114	oxidation-reduction process

0.79	GO:0005351	sugar:proton symporter activity
0.48	GO:0005463	UDP-N-acetylgalactosamine transmembrane transporter activity
0.48	GO:0005459	UDP-galactose transmembrane transporter activity
0.38	GO:0005456	CMP-N-acetylneuraminate transmembrane transporter activity
0.38	GO:0005461	UDP-glucuronic acid transmembrane transporter activity
0.37	GO:0005464	UDP-xylose transmembrane transporter activity

0.74	GO:0000139	Golgi membrane
0.46	GO:0005797	Golgi medial cisterna
0.35	GO:0031301	integral component of organelle membrane
0.34	GO:0005783	endoplasmic reticulum
0.33	GO:0005634	nucleus

tr|T1FWA4|T1FWA4_HELRO
Uncharacterized protein
Search

tr|T1FWA5|T1FWA5_HELRO
Uncharacterized protein
Search

tr|T1FWA6|T1FWA6_HELRO
Uncharacterized protein
Search

0.36	GO:0018205	peptidyl-lysine modification
0.36	GO:0016571	histone methylation
0.35	GO:1903288	positive regulation of potassium ion import
0.35	GO:0006468	protein phosphorylation
0.35	GO:0006508	proteolysis
0.34	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.34	GO:0035220	wing disc development
0.34	GO:0007411	axon guidance
0.34	GO:0070647	protein modification by small protein conjugation or removal
0.34	GO:0006367	transcription initiation from RNA polymerase II promoter

0.49	GO:0003676	nucleic acid binding
0.37	GO:0140096	catalytic activity, acting on a protein
0.36	GO:0016278	lysine N-methyltransferase activity
0.35	GO:0016301	kinase activity
0.35	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.34	GO:0046872	metal ion binding
0.34	GO:0140110	transcription regulator activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.36	GO:0044666	MLL3/4 complex
0.34	GO:0005730	nucleolus
0.34	GO:0016592	mediator complex
0.33	GO:0010008	endosome membrane
0.30	GO:0031224	intrinsic component of membrane

0.36

GO:0016278

tr|T1FWA7|T1FWA7_HELRO
Uncharacterized protein
Search

0.76	GO:0097742	de novo centriole assembly
0.76	GO:1903251	multi-ciliated epithelial cell differentiation
0.73	GO:0007099	centriole replication
0.47	GO:0007018	microtubule-based movement
0.40	GO:0006468	protein phosphorylation
0.37	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
0.37	GO:0000070	mitotic sister chromatid segregation
0.37	GO:0055114	oxidation-reduction process
0.36	GO:0043933	macromolecular complex subunit organization
0.36	GO:0022411	cellular component disassembly

0.47	GO:0003777	microtubule motor activity
0.46	GO:0008017	microtubule binding
0.42	GO:0030554	adenyl nucleotide binding
0.42	GO:0097367	carbohydrate derivative binding
0.42	GO:0008144	drug binding
0.42	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0004672	protein kinase activity
0.37	GO:0016491	oxidoreductase activity
0.36	GO:0043515	kinetochore binding
0.36	GO:0004888	transmembrane signaling receptor activity

0.76	GO:0098536	deuterosome
0.65	GO:0005815	microtubule organizing center
0.37	GO:0005871	kinesin complex
0.36	GO:0005911	cell-cell junction
0.36	GO:0005828	kinetochore microtubule
0.36	GO:1990023	mitotic spindle midzone
0.35	GO:0031981	nuclear lumen
0.35	GO:0030496	midbody
0.35	GO:0000940	condensed chromosome outer kinetochore
0.35	GO:0005829	cytosol

0.37

GO:0016491

tr|T1FWA8|T1FWA8_HELRO
Uncharacterized protein
Search

0.61

GO:0006508

proteolysis

0.67	GO:0008236	serine-type peptidase activity
0.36	GO:0004177	aminopeptidase activity
0.34	GO:0042802	identical protein binding
0.34	GO:0004175	endopeptidase activity

0.34	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.36

EC:3.4.11

GO:0004177

tr|T1FWA9|T1FWA9_HELRO
Transgelin
Search

0.10	Transgelin

tr|T1FWB0|T1FWB0_HELRO
Uncharacterized protein
Search

0.83	GO:0006471	protein ADP-ribosylation
0.51	GO:0006281	DNA repair
0.51	GO:0097191	extrinsic apoptotic signaling pathway
0.49	GO:0006273	lagging strand elongation
0.49	GO:0018209	peptidyl-serine modification
0.48	GO:0051106	positive regulation of DNA ligation
0.48	GO:1990166	protein localization to site of double-strand break
0.47	GO:0006266	DNA ligation
0.46	GO:0060236	regulation of mitotic spindle organization
0.44	GO:0000723	telomere maintenance

0.81	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.54	GO:1990404	protein ADP-ribosylase activity
0.48	GO:0003910	DNA ligase (ATP) activity
0.41	GO:0008270	zinc ion binding
0.34	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity
0.34	GO:0005515	protein binding
0.33	GO:0003677	DNA binding

0.46	GO:0005730	nucleolus
0.45	GO:0035861	site of double-strand break
0.45	GO:0005654	nucleoplasm
0.37	GO:0005737	cytoplasm
0.33	GO:0055044	symplast
0.33	GO:0070062	extracellular exosome
0.33	GO:0099023	tethering complex
0.33	GO:0005911	cell-cell junction
0.33	GO:0005815	microtubule organizing center
0.32	GO:0043234	protein complex

0.81

EC:2.4.2.30

GO:0003950

tr|T1FWB1|T1FWB1_HELRO
Uncharacterized protein
Search

0.59	GO:1902960	negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
0.59	GO:1902771	positive regulation of choline O-acetyltransferase activity
0.59	GO:1902955	positive regulation of early endosome to recycling endosome transport
0.59	GO:1902997	negative regulation of neurofibrillary tangle assembly
0.59	GO:1902948	negative regulation of tau-protein kinase activity
0.58	GO:1902963	negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
0.58	GO:1902953	positive regulation of ER to Golgi vesicle-mediated transport
0.57	GO:2001137	positive regulation of endocytic recycling
0.57	GO:1902430	negative regulation of amyloid-beta formation
0.57	GO:1902965	regulation of protein localization to early endosome

0.57	GO:0071814	protein-lipid complex binding
0.56	GO:0030306	ADP-ribosylation factor binding
0.55	GO:0001540	amyloid-beta binding
0.51	GO:0005509	calcium ion binding
0.41	GO:0030228	lipoprotein particle receptor activity
0.37	GO:0034437	glycoprotein transporter activity
0.37	GO:0034185	apolipoprotein binding
0.37	GO:0048306	calcium-dependent protein binding
0.36	GO:0004888	transmembrane signaling receptor activity
0.35	GO:0003779	actin binding

0.63	GO:0005794	Golgi apparatus
0.56	GO:0005641	nuclear envelope lumen
0.53	GO:0055037	recycling endosome
0.52	GO:0005769	early endosome
0.50	GO:0005615	extracellular space
0.49	GO:0005783	endoplasmic reticulum
0.47	GO:0031984	organelle subcompartment
0.41	GO:1990777	lipoprotein particle
0.40	GO:0043235	receptor complex
0.40	GO:0016324	apical plasma membrane

0.32

GO:0008168

tr|T1FWB2|T1FWB2_HELRO
Uncharacterized protein
Search

tr|T1FWB3|T1FWB3_HELRO
Uncharacterized protein
Search

tr|T1FWB4|T1FWB4_HELRO
Uncharacterized protein
Search

0.37	GO:0043412	macromolecule modification
0.36	GO:0006913	nucleocytoplasmic transport
0.36	GO:0000973	posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery
0.36	GO:0034398	telomere tethering at nuclear periphery
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:0010468	regulation of gene expression
0.36	GO:0008033	tRNA processing
0.36	GO:0036065	fucosylation
0.36	GO:0031505	fungal-type cell wall organization

0.48	GO:0003676	nucleic acid binding
0.37	GO:0033218	amide binding
0.37	GO:0017056	structural constituent of nuclear pore
0.37	GO:0033830	Skp1-protein-hydroxyproline N-acetylglucosaminyltransferase activity
0.37	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity
0.36	GO:0033293	monocarboxylic acid binding
0.36	GO:0008193	tRNA guanylyltransferase activity
0.36	GO:0046872	metal ion binding
0.36	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity
0.36	GO:0008107	galactoside 2-alpha-L-fucosyltransferase activity

0.37	GO:0005643	nuclear pore
0.36	GO:0031362	anchored component of external side of plasma membrane
0.36	GO:0008023	transcription elongation factor complex
0.35	GO:0009277	fungal-type cell wall
0.34	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.37

EC:2.4.1.229

GO:0033830

tr|T1FWB5|T1FWB5_HELRO
Uncharacterized protein
Search

0.80	GO:0007229	integrin-mediated signaling pathway
0.72	GO:0007155	cell adhesion
0.36	GO:0007432	salivary gland boundary specification
0.36	GO:0035160	maintenance of epithelial integrity, open tracheal system
0.36	GO:0048567	ectodermal digestive tract morphogenesis
0.36	GO:0007414	axonal defasciculation
0.36	GO:0007475	apposition of dorsal and ventral imaginal disc-derived wing surfaces
0.36	GO:0007426	tracheal outgrowth, open tracheal system
0.36	GO:0007427	epithelial cell migration, open tracheal system
0.36	GO:0007494	midgut development

0.35	GO:0050840	extracellular matrix binding
0.35	GO:0004621	glycosylphosphatidylinositol phospholipase D activity
0.35	GO:0050839	cell adhesion molecule binding
0.34	GO:0046982	protein heterodimerization activity
0.34	GO:0003777	microtubule motor activity
0.34	GO:0008017	microtubule binding
0.34	GO:0004872	receptor activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.81	GO:0008305	integrin complex
0.36	GO:0009925	basal plasma membrane
0.35	GO:0016328	lateral plasma membrane
0.35	GO:0005925	focal adhesion
0.35	GO:0016324	apical plasma membrane

0.35

EC:3.1.4.50

GO:0004621

tr|T1FWB6|T1FWB6_HELRO
Uncharacterized protein
Search

0.83	Putative ubiquitin carboxyl-terminal hydrolase 6

0.66	GO:0031338	regulation of vesicle fusion
0.66	GO:0090630	activation of GTPase activity
0.65	GO:0035526	retrograde transport, plasma membrane to Golgi
0.63	GO:0048227	plasma membrane to endosome transport
0.62	GO:1903358	regulation of Golgi organization
0.58	GO:0007030	Golgi organization
0.56	GO:0006886	intracellular protein transport
0.52	GO:0019068	virion assembly

0.70	GO:0017137	Rab GTPase binding
0.66	GO:0005096	GTPase activator activity
0.40	GO:0016787	hydrolase activity

0.55	GO:0012505	endomembrane system
0.53	GO:0031410	cytoplasmic vesicle
0.44	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.40

GO:0016787

tr|T1FWB7|T1FWB7_HELRO
Uncharacterized protein
Search

tr|T1FWB8|T1FWB8_HELRO
Uncharacterized protein
Search

0.49	GO:0007098	centrosome cycle
0.43	GO:0006950	response to stress
0.41	GO:0051716	cellular response to stimulus
0.41	GO:0031667	response to nutrient levels
0.41	GO:0006468	protein phosphorylation
0.40	GO:0006886	intracellular protein transport
0.39	GO:0065007	biological regulation
0.39	GO:0098754	detoxification
0.38	GO:0006310	DNA recombination
0.37	GO:0023052	signaling

0.42	GO:0008430	selenium binding
0.41	GO:0004672	protein kinase activity
0.40	GO:0004930	G-protein coupled receptor activity
0.39	GO:0004601	peroxidase activity
0.39	GO:0004222	metalloendopeptidase activity
0.39	GO:0046983	protein dimerization activity
0.38	GO:0032559	adenyl ribonucleotide binding
0.38	GO:0043565	sequence-specific DNA binding
0.38	GO:0008144	drug binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding

0.51	GO:0035253	ciliary rootlet
0.42	GO:0030915	Smc5-Smc6 complex
0.42	GO:0005634	nucleus
0.40	GO:0005667	transcription factor complex
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.39	EC:1.11.1.7	GO:0004601
0.39	KEGG:R03532	GO:0004601

tr|T1FWB9|T1FWB9_HELRO
Uncharacterized protein
Search

tr|T1FWC0|T1FWC0_HELRO
Uncharacterized protein
Search

0.92	Fibroblast growth factor (Acidic) intracellular binding protein a

0.85

GO:0017134

fibroblast growth factor binding

0.30

GO:0044425

membrane part

tr|T1FWC1|T1FWC1_HELRO
Uncharacterized protein
Search

tr|T1FWC2|T1FWC2_HELRO
Uncharacterized protein
Search

tr|T1FWC3|T1FWC3_HELRO
Uncharacterized protein
Search

0.62	GO:0007160	cell-matrix adhesion
0.39	GO:0007099	centriole replication
0.39	GO:0032958	inositol phosphate biosynthetic process
0.39	GO:0036211	protein modification process
0.38	GO:0032465	regulation of cytokinesis
0.38	GO:0006511	ubiquitin-dependent protein catabolic process
0.38	GO:0035023	regulation of Rho protein signal transduction
0.37	GO:0016569	covalent chromatin modification
0.37	GO:0009405	pathogenesis
0.37	GO:0016310	phosphorylation

0.55	GO:0005509	calcium ion binding
0.39	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.39	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.38	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.38	GO:0008658	penicillin binding
0.37	GO:0016301	kinase activity
0.37	GO:0008270	zinc ion binding
0.36	GO:0003676	nucleic acid binding
0.36	GO:0004872	receptor activity
0.35	GO:0016773	phosphotransferase activity, alcohol group as acceptor

0.53	GO:0005576	extracellular region
0.45	GO:0005680	anaphase-promoting complex
0.39	GO:0005814	centriole
0.30	GO:0016020	membrane

0.39

EC:3.4.19.12

GO:0036459

tr|T1FWC4|T1FWC4_HELRO
Uncharacterized protein
Search

tr|T1FWC5|T1FWC5_HELRO
Uncharacterized protein
Search

0.55	GO:0055085	transmembrane transport
0.40	GO:0006869	lipid transport
0.35	GO:0048730	epidermis morphogenesis

0.66	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.45	GO:0097208	alveolar lamellar body
0.42	GO:0097232	lamellar body membrane
0.36	GO:0005886	plasma membrane
0.36	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

tr|T1FWC6|T1FWC6_HELRO
Uncharacterized protein
Search

tr|T1FWC7|T1FWC7_HELRO
Uncharacterized protein
Search

tr|T1FWC8|T1FWC8_HELRO
Uncharacterized protein
Search

tr|T1FWC9|T1FWC9_HELRO
Uncharacterized protein
Search

tr|T1FWD0|T1FWD0_HELRO
Uncharacterized protein
Search

0.69

GO:0016192

vesicle-mediated transport

0.30

GO:0044425

membrane part

tr|T1FWD1|T1FWD1_HELRO
Uncharacterized protein
Search

0.73	GO:0007018	microtubule-based movement
0.37	GO:0001558	regulation of cell growth
0.37	GO:0048057	R3/R4 development
0.37	GO:0090419	negative regulation of transcription involved in G2/M transition of mitotic cell cycle
0.37	GO:1903468	positive regulation of DNA replication initiation
0.37	GO:0090282	positive regulation of transcription involved in G2/M transition of mitotic cell cycle
0.36	GO:0070785	negative regulation of growth of unicellular organism as a thread of attached cells
0.36	GO:0071930	negative regulation of transcription involved in G1/S transition of mitotic cell cycle
0.36	GO:0070593	dendrite self-avoidance
0.36	GO:0016318	ommatidial rotation

0.74	GO:0003777	microtubule motor activity
0.73	GO:0008017	microtubule binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0008144	drug binding
0.36	GO:0001085	RNA polymerase II transcription factor binding
0.35	GO:0005057	signal transducer activity, downstream of receptor
0.35	GO:0003688	DNA replication origin binding
0.35	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding

0.37	GO:0005871	kinesin complex
0.35	GO:0005911	cell-cell junction
0.35	GO:0000139	Golgi membrane
0.34	GO:0005829	cytosol
0.33	GO:0005634	nucleus
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.35

GO:0016887

tr|T1FWD2|T1FWD2_HELRO
Uncharacterized protein
Search

tr|T1FWD3|T1FWD3_HELRO
Uncharacterized protein
Search

tr|T1FWD4|T1FWD4_HELRO
Uncharacterized protein
Search

0.56	Electroneutral potassium-chloride cotransporter 1

0.86	GO:0071477	cellular hypotonic salinity response
0.77	GO:1902476	chloride transmembrane transport
0.47	GO:0007638	mechanosensory behavior
0.38	GO:0003333	amino acid transmembrane transport
0.36	GO:0007268	chemical synaptic transmission
0.35	GO:0071805	potassium ion transmembrane transport
0.34	GO:0006884	cell volume homeostasis

0.85	GO:0015379	potassium:chloride symporter activity
0.38	GO:0015171	amino acid transmembrane transporter activity
0.36	GO:0022820	potassium ion symporter activity

0.67	GO:0005887	integral component of plasma membrane
0.45	GO:0043025	neuronal cell body
0.45	GO:0030424	axon

tr|T1FWD5|T1FWD5_HELRO
Uncharacterized protein
Search

tr|T1FWD6|T1FWD6_HELRO
Chloride channel protein
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CLCN7

0.52	Chloride channel protein (Fragment)

0.76	GO:1902476	chloride transmembrane transport
0.34	GO:0009268	response to pH

0.77

GO:0005247

voltage-gated chloride channel activity

0.45	GO:0005654	nucleoplasm
0.34	GO:0031410	cytoplasmic vesicle
0.30	GO:0031224	intrinsic component of membrane

tr|T1FWD7|T1FWD7_HELRO
Uncharacterized protein
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tr|T1FWD8|T1FWD8_HELRO
Calcium-transporting ATPase
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0.58	Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type

0.77	GO:0070588	calcium ion transmembrane transport
0.69	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.37	GO:0044057	regulation of system process
0.35	GO:0051241	negative regulation of multicellular organismal process
0.35	GO:0090076	relaxation of skeletal muscle
0.34	GO:0001947	heart looping
0.34	GO:0009612	response to mechanical stimulus
0.34	GO:0006874	cellular calcium ion homeostasis
0.34	GO:0051240	positive regulation of multicellular organismal process

0.80	GO:0005388	calcium-transporting ATPase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005509	calcium ion binding

0.36	GO:0033017	sarcoplasmic reticulum membrane
0.35	GO:0031673	H zone
0.34	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.34	GO:0031674	I band
0.34	GO:0048471	perinuclear region of cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.80

EC:3.6.3.8

GO:0005388

tr|T1FWD9|T1FWD9_HELRO
Uncharacterized protein
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tr|T1FWE0|T1FWE0_HELRO
Uncharacterized protein
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0.61	GO:0005977	glycogen metabolic process
0.58	GO:2000465	regulation of glycogen (starch) synthase activity
0.58	GO:0005979	regulation of glycogen biosynthetic process
0.40	GO:0005981	regulation of glycogen catabolic process
0.40	GO:0016192	vesicle-mediated transport
0.40	GO:0043044	ATP-dependent chromatin remodeling
0.37	GO:0006470	protein dephosphorylation
0.37	GO:0042254	ribosome biogenesis
0.36	GO:0006396	RNA processing
0.36	GO:0032784	regulation of DNA-templated transcription, elongation

0.58	GO:2001069	glycogen binding
0.54	GO:0019903	protein phosphatase binding
0.37	GO:0004386	helicase activity
0.37	GO:0000991	transcription factor activity, core RNA polymerase II binding
0.37	GO:0004721	phosphoprotein phosphatase activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0043565	sequence-specific DNA binding
0.35	GO:0008270	zinc ion binding

0.41	GO:0042587	glycogen granule
0.38	GO:0005730	nucleolus
0.30	GO:0016020	membrane

0.37

EC:3.1.3.16

GO:0004721

tr|T1FWE1|T1FWE1_HELRO
Uncharacterized protein
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tr|T1FWE2|T1FWE2_HELRO
Uncharacterized protein
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0.45	GO:0016567	protein ubiquitination
0.41	GO:1903506	regulation of nucleic acid-templated transcription
0.41	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.41	GO:0010468	regulation of gene expression
0.41	GO:0006886	intracellular protein transport
0.41	GO:0016192	vesicle-mediated transport
0.38	GO:0006413	translational initiation
0.37	GO:0031156	regulation of sorocarp development
0.37	GO:1902680	positive regulation of RNA biosynthetic process
0.37	GO:0032502	developmental process

0.45	GO:0004842	ubiquitin-protein transferase activity
0.42	GO:0003700	DNA binding transcription factor activity
0.41	GO:0003723	RNA binding
0.39	GO:0005198	structural molecule activity
0.37	GO:0003677	DNA binding
0.37	GO:0001085	RNA polymerase II transcription factor binding
0.36	GO:0008270	zinc ion binding
0.36	GO:0016874	ligase activity
0.36	GO:0003682	chromatin binding
0.36	GO:0001067	regulatory region nucleic acid binding

0.43	GO:0030126	COPI vesicle coat
0.38	GO:0005634	nucleus
0.36	GO:0005667	transcription factor complex
0.35	GO:0005576	extracellular region
0.35	GO:0043232	intracellular non-membrane-bounded organelle
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0000178	exosome (RNase complex)
0.33	GO:1904949	ATPase complex
0.33	GO:0033202	DNA helicase complex
0.33	GO:0030529	intracellular ribonucleoprotein complex

0.36	EC:6	GO:0016874
0.45	KEGG:R03876	GO:0004842

tr|T1FWE3|T1FWE3_HELRO
Uncharacterized protein
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tr|T1FWE4|T1FWE4_HELRO
Uncharacterized protein
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0.45	GO:0045944	positive regulation of transcription by RNA polymerase II
0.39	GO:0007296	vitellogenesis
0.39	GO:0048146	positive regulation of fibroblast proliferation
0.38	GO:0048844	artery morphogenesis
0.38	GO:0045582	positive regulation of T cell differentiation
0.38	GO:0001570	vasculogenesis
0.38	GO:0045747	positive regulation of Notch signaling pathway
0.38	GO:0007569	cell aging
0.38	GO:0003007	heart morphogenesis
0.38	GO:0048589	developmental growth

0.63	GO:0008270	zinc ion binding
0.47	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.37	GO:0016874	ligase activity
0.33	GO:0005515	protein binding

0.46	GO:0043596	nuclear replication fork
0.43	GO:0005654	nucleoplasm
0.39	GO:0005739	mitochondrion

0.37

GO:0016874

tr|T1FWE5|T1FWE5_HELRO
Uncharacterized protein
Search

0.52	GO:0007296	vitellogenesis
0.51	GO:0048146	positive regulation of fibroblast proliferation
0.50	GO:0048844	artery morphogenesis
0.50	GO:0045582	positive regulation of T cell differentiation
0.50	GO:0001570	vasculogenesis
0.50	GO:0045747	positive regulation of Notch signaling pathway
0.49	GO:0007569	cell aging
0.49	GO:0003007	heart morphogenesis
0.48	GO:0048589	developmental growth
0.48	GO:0001701	in utero embryonic development

0.62	GO:0008270	zinc ion binding
0.34	GO:0019706	protein-cysteine S-palmitoyltransferase activity
0.34	GO:0016874	ligase activity
0.33	GO:0005515	protein binding
0.33	GO:0005509	calcium ion binding

0.45	GO:0005654	nucleoplasm
0.32	GO:0005737	cytoplasm
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.34

GO:0019706

tr|T1FWE6|T1FWE6_HELRO
Uncharacterized protein
Search

0.57	GO:0048015	phosphatidylinositol-mediated signaling
0.53	GO:0021707	cerebellar granule cell differentiation
0.53	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.52	GO:0021702	cerebellar Purkinje cell differentiation
0.51	GO:0016266	O-glycan processing
0.50	GO:0046530	photoreceptor cell differentiation
0.49	GO:0043009	chordate embryonic development
0.47	GO:0005975	carbohydrate metabolic process

0.50	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.49	GO:0005201	extracellular matrix structural constituent
0.48	GO:0008061	chitin binding
0.47	GO:0030246	carbohydrate binding

0.60	GO:0070701	mucus layer
0.53	GO:0005615	extracellular space
0.52	GO:0005796	Golgi lumen
0.49	GO:1903561	extracellular vesicle
0.40	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.50

GO:0004553

tr|T1FWE7|T1FWE7_HELRO
Uncharacterized protein
Search

0.75	GO:0006517	protein deglycosylation
0.68	GO:0006044	N-acetylglucosamine metabolic process
0.40	GO:0010616	negative regulation of cardiac muscle adaptation
0.40	GO:0060051	negative regulation of protein glycosylation
0.40	GO:0046060	dATP metabolic process
0.40	GO:0051901	positive regulation of mitochondrial depolarization
0.40	GO:0060124	positive regulation of growth hormone secretion
0.39	GO:0046326	positive regulation of glucose import
0.39	GO:0010524	positive regulation of calcium ion transport into cytosol
0.39	GO:0070265	necrotic cell death

0.86	GO:0016231	beta-N-acetylglucosaminidase activity
0.47	GO:0102571	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity
0.47	GO:0102166	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity
0.47	GO:0102167	[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity
0.39	GO:0004415	hyalurononglucosaminidase activity
0.38	GO:0004402	histone acetyltransferase activity
0.36	GO:0005515	protein binding

0.61	GO:0005829	cytosol
0.39	GO:0005634	nucleus
0.35	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

0.47

EC:3.2.1.169

GO:0102571

tr|T1FWE8|T1FWE8_HELRO
Uncharacterized protein
Search

FUT8

0.89	Alpha-(1,6)-fucosyltransferase

0.80	GO:0036071	N-glycan fucosylation
0.80	GO:0033578	protein glycosylation in Golgi
0.54	GO:0018279	protein N-linked glycosylation via asparagine
0.53	GO:0046368	GDP-L-fucose metabolic process
0.52	GO:0007585	respiratory gaseous exchange
0.51	GO:1900407	regulation of cellular response to oxidative stress
0.51	GO:0006491	N-glycan processing
0.51	GO:0007179	transforming growth factor beta receptor signaling pathway
0.50	GO:0043112	receptor metabolic process
0.49	GO:0007229	integrin-mediated signaling pathway

0.81	GO:0008424	glycoprotein 6-alpha-L-fucosyltransferase activity
0.41	GO:0017124	SH3 domain binding
0.39	GO:0046702	galactoside 6-L-fucosyltransferase activity
0.32	GO:0046872	metal ion binding
0.32	GO:0016491	oxidoreductase activity

0.72	GO:0032580	Golgi cisterna membrane
0.46	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.81	EC:2.4.1.68	GO:0008424
0.81	KEGG:R05988	GO:0008424

tr|T1FWE9|T1FWE9_HELRO
Uncharacterized protein
Search

0.51	GO:0043402	glucocorticoid mediated signaling pathway
0.50	GO:0042921	glucocorticoid receptor signaling pathway
0.47	GO:0042332	gravitaxis
0.43	GO:0006351	transcription, DNA-templated
0.43	GO:1903506	regulation of nucleic acid-templated transcription
0.42	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.41	GO:0010468	regulation of gene expression
0.37	GO:0006886	intracellular protein transport

0.51	GO:0004883	glucocorticoid receptor activity
0.48	GO:0005496	steroid binding
0.47	GO:0003676	nucleic acid binding
0.44	GO:0140110	transcription regulator activity
0.41	GO:0008270	zinc ion binding
0.40	GO:0032559	adenyl ribonucleotide binding
0.39	GO:0008144	drug binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0016887	ATPase activity

0.47	GO:0005634	nucleus
0.44	GO:0031974	membrane-enclosed lumen
0.42	GO:1990234	transferase complex
0.41	GO:0005667	transcription factor complex
0.40	GO:0044446	intracellular organelle part
0.38	GO:1905368	peptidase complex
0.30	GO:0016020	membrane

0.35

GO:0016887

tr|T1FWF0|T1FWF0_HELRO
Uncharacterized protein
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tr|T1FWF1|T1FWF1_HELRO
Uncharacterized protein
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0.14	box C/D snoRNA protein 1-like

0.59	GO:0048254	snoRNA localization
0.57	GO:0000492	box C/D snoRNP assembly
0.50	GO:0051259	protein oligomerization
0.40	GO:0042254	ribosome biogenesis

0.58	GO:0001094	TFIID-class transcription factor binding
0.56	GO:0051117	ATPase binding
0.54	GO:0046872	metal ion binding
0.50	GO:0042802	identical protein binding

0.58

GO:0070761

pre-snoRNP complex

tr|T1FWF2|T1FWF2_HELRO
Uncharacterized protein
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tr|T1FWF3|T1FWF3_HELRO
Uncharacterized protein
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0.77	GO:0006887	exocytosis
0.48	GO:0051601	exocyst localization
0.47	GO:0022617	extracellular matrix disassembly
0.45	GO:0007032	endosome organization
0.45	GO:0048278	vesicle docking
0.42	GO:0043623	cellular protein complex assembly
0.35	GO:0015031	protein transport
0.33	GO:0016241	regulation of macroautophagy
0.32	GO:0055114	oxidation-reduction process

0.46	GO:0017160	Ral GTPase binding
0.33	GO:0031418	L-ascorbic acid binding
0.32	GO:0035091	phosphatidylinositol binding
0.32	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.32	GO:0005506	iron ion binding

0.79	GO:0000145	exocyst
0.44	GO:0005770	late endosome
0.41	GO:0005829	cytosol
0.38	GO:0030426	growth cone
0.37	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0031252	cell leading edge
0.33	GO:0097546	ciliary base
0.33	GO:0097731	9+0 non-motile cilium
0.32	GO:0005886	plasma membrane

0.32

GO:0016705

tr|T1FWF4|T1FWF4_HELRO
Uncharacterized protein
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tr|T1FWF5|T1FWF5_HELRO
Uncharacterized protein
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tr|T1FWF6|T1FWF6_HELRO
Uncharacterized protein
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tr|T1FWF7|T1FWF7_HELRO
Uncharacterized protein
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tr|T1FWF8|T1FWF8_HELRO
Uncharacterized protein
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tr|T1FWF9|T1FWF9_HELRO
Uncharacterized protein
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tr|T1FWG0|T1FWG0_HELRO
Uncharacterized protein
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tr|T1FWG1|T1FWG1_HELRO
Uncharacterized protein
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tr|T1FWG2|T1FWG2_HELRO
Uncharacterized protein
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0.61	GO:0006508	proteolysis
0.43	GO:0051604	protein maturation
0.40	GO:0006518	peptide metabolic process
0.36	GO:1901142	insulin metabolic process
0.35	GO:0051384	response to glucocorticoid
0.34	GO:0042445	hormone metabolic process
0.34	GO:0006501	C-terminal protein lipidation
0.33	GO:1901575	organic substance catabolic process
0.33	GO:0042737	drug catabolic process
0.33	GO:0005976	polysaccharide metabolic process

0.77	GO:0004181	metallocarboxypeptidase activity
0.63	GO:0008270	zinc ion binding
0.53	GO:0004185	serine-type carboxypeptidase activity
0.34	GO:0030246	carbohydrate binding
0.32	GO:0004197	cysteine-type endopeptidase activity
0.32	GO:0005509	calcium ion binding
0.32	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.32	GO:0016301	kinase activity

0.44	GO:0005615	extracellular space
0.40	GO:0009986	cell surface
0.35	GO:0031982	vesicle
0.35	GO:0031225	anchored component of membrane
0.35	GO:0043025	neuronal cell body
0.35	GO:0097060	synaptic membrane
0.34	GO:0043230	extracellular organelle
0.34	GO:0005794	Golgi apparatus
0.30	GO:0016021	integral component of membrane

0.77

GO:0004181

tr|T1FWG3|T1FWG3_HELRO
Uncharacterized protein
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tr|T1FWG4|T1FWG4_HELRO
Uncharacterized protein
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tr|T1FWG5|T1FWG5_HELRO
Uncharacterized protein
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0.75	DEAD box polypeptide 3 Y-linked short isoform

0.48	GO:0010501	RNA secondary structure unwinding
0.45	GO:0007059	chromosome segregation
0.44	GO:0006413	translational initiation
0.39	GO:0010468	regulation of gene expression

0.67	GO:0004386	helicase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0003676	nucleic acid binding
0.46	GO:0008186	RNA-dependent ATPase activity
0.41	GO:0140098	catalytic activity, acting on RNA

0.47	GO:0036464	cytoplasmic ribonucleoprotein granule
0.45	GO:0005730	nucleolus
0.30	GO:0031224	intrinsic component of membrane

tr|T1FWG6|T1FWG6_HELRO
Uncharacterized protein
Search

0.60	Hippocampus abundant transcript protein 1

0.55

GO:0055085

transmembrane transport

0.56

GO:0005215

transporter activity

0.30

GO:0044425

membrane part

tr|T1FWG7|T1FWG7_HELRO
Uncharacterized protein
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tr|T1FWG8|T1FWG8_HELRO
Uncharacterized protein
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CAMK4

0.77	Calcium/calmodulin-dependent protein kinase type IV

0.63	GO:0006468	protein phosphorylation
0.53	GO:0043011	myeloid dendritic cell differentiation
0.52	GO:0007616	long-term memory
0.49	GO:0045893	positive regulation of transcription, DNA-templated
0.48	GO:0018209	peptidyl-serine modification
0.41	GO:0035556	intracellular signal transduction
0.39	GO:0060216	definitive hemopoiesis
0.38	GO:0002372	myeloid dendritic cell cytokine production
0.37	GO:0002250	adaptive immune response
0.37	GO:0006954	inflammatory response

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0005516	calmodulin binding
0.35	GO:0046875	ephrin receptor binding

0.50	GO:0001650	fibrillar center
0.45	GO:0005654	nucleoplasm
0.37	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

tr|T1FWG9|T1FWG9_HELRO
Uncharacterized protein
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tr|T1FWH0|T1FWH0_HELRO
Uncharacterized protein
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tr|T1FWH1|T1FWH1_HELRO
Uncharacterized protein
Search

0.69	GO:0007298	border follicle cell migration
0.44	GO:0043547	positive regulation of GTPase activity
0.40	GO:0045454	cell redox homeostasis

0.45	GO:0005096	GTPase activator activity
0.35	GO:0016787	hydrolase activity

0.30	GO:0031224	intrinsic component of membrane
0.30	GO:0005623	cell

0.35

GO:0016787

tr|T1FWH2|T1FWH2_HELRO
Uncharacterized protein
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tr|T1FWH3|T1FWH3_HELRO
Uncharacterized protein
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tr|T1FWH4|T1FWH4_HELRO
Uncharacterized protein
Search

0.42	GO:0099120	socially cooperative development
0.42	GO:0060255	regulation of macromolecule metabolic process
0.41	GO:0031323	regulation of cellular metabolic process
0.41	GO:0051171	regulation of nitrogen compound metabolic process
0.41	GO:0080090	regulation of primary metabolic process
0.41	GO:0009889	regulation of biosynthetic process
0.41	GO:0006325	chromatin organization
0.40	GO:0031156	regulation of sorocarp development
0.38	GO:0036211	protein modification process
0.38	GO:0016070	RNA metabolic process

0.42	GO:0003700	DNA binding transcription factor activity
0.39	GO:0046872	metal ion binding
0.39	GO:0017111	nucleoside-triphosphatase activity
0.39	GO:0044212	transcription regulatory region DNA binding
0.39	GO:0017076	purine nucleotide binding
0.39	GO:0097367	carbohydrate derivative binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0016301	kinase activity
0.38	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.38	GO:0140096	catalytic activity, acting on a protein

0.43	GO:0005634	nucleus
0.40	GO:0033202	DNA helicase complex
0.39	GO:0070013	intracellular organelle lumen
0.39	GO:0000785	chromatin
0.38	GO:1904949	ATPase complex
0.36	GO:0005576	extracellular region
0.36	GO:0043234	protein complex
0.35	GO:0010494	cytoplasmic stress granule
0.35	GO:1990234	transferase complex
0.34	GO:0005829	cytosol

0.39	EC:3.6.1.15	GO:0017111
0.34	KEGG:R03665	GO:0004832

tr|T1FWH5|T1FWH5_HELRO
Uncharacterized protein
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tr|T1FWH6|T1FWH6_HELRO
Uncharacterized protein
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tr|T1FWH7|T1FWH7_HELRO
Uncharacterized protein
Search

0.43	GO:0006468	protein phosphorylation
0.42	GO:0006030	chitin metabolic process
0.41	GO:0008643	carbohydrate transport
0.39	GO:0043326	chemotaxis to folate
0.39	GO:0060176	regulation of aggregation involved in sorocarp development
0.39	GO:0043327	chemotaxis to cAMP
0.39	GO:0031272	regulation of pseudopodium assembly
0.39	GO:0055085	transmembrane transport
0.38	GO:0031087	deadenylation-independent decapping of nuclear-transcribed mRNA
0.38	GO:0030245	cellulose catabolic process

0.43	GO:0140096	catalytic activity, acting on a protein
0.42	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.42	GO:0008061	chitin binding
0.42	GO:0016301	kinase activity
0.41	GO:0030246	carbohydrate binding
0.40	GO:0032559	adenyl ribonucleotide binding
0.40	GO:0043168	anion binding
0.38	GO:0046982	protein heterodimerization activity
0.37	GO:0016409	palmitoyltransferase activity
0.37	GO:0003700	DNA binding transcription factor activity

0.40	GO:0005576	extracellular region
0.38	GO:0020011	apicoplast
0.38	GO:0005838	proteasome regulatory particle
0.38	GO:0005881	cytoplasmic microtubule
0.37	GO:0000932	P-body
0.37	GO:0005815	microtubule organizing center
0.30	GO:0016020	membrane

0.42

GO:0016773

tr|T1FWH8|T1FWH8_HELRO
Uncharacterized protein
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tr|T1FWH9|T1FWH9_HELRO
Uncharacterized protein
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0.55	GO:0006914	autophagy
0.49	GO:0008104	protein localization
0.48	GO:0042886	amide transport
0.47	GO:0071702	organic substance transport
0.46	GO:0006508	proteolysis
0.40	GO:0016567	protein ubiquitination
0.39	GO:0006629	lipid metabolic process
0.39	GO:0048015	phosphatidylinositol-mediated signaling
0.37	GO:0007018	microtubule-based movement
0.37	GO:1901575	organic substance catabolic process

0.52	GO:0008234	cysteine-type peptidase activity
0.40	GO:0004842	ubiquitin-protein transferase activity
0.40	GO:0003924	GTPase activity
0.39	GO:0005525	GTP binding
0.38	GO:0003777	microtubule motor activity
0.37	GO:0003700	DNA binding transcription factor activity
0.37	GO:0046872	metal ion binding
0.36	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.36	GO:0016301	kinase activity
0.36	GO:0003676	nucleic acid binding

0.40	GO:0005737	cytoplasm
0.37	GO:0005634	nucleus
0.36	GO:0070013	intracellular organelle lumen
0.36	GO:1990234	transferase complex
0.35	GO:0044446	intracellular organelle part
0.34	GO:0005929	cilium
0.34	GO:0070263	external side of fungal-type cell wall
0.34	GO:0012505	endomembrane system
0.33	GO:0031362	anchored component of external side of plasma membrane
0.33	GO:0005694	chromosome

0.52	EC:3.4	GO:0008234
0.40	KEGG:R03876	GO:0004842

tr|T1FWI0|T1FWI0_HELRO
Uncharacterized protein
Search

DHRS7B

0.59	11beta hydroxysteroid dehydrogenase type 1

0.52	GO:0055114	oxidation-reduction process
0.33	GO:0016485	protein processing
0.33	GO:0007017	microtubule-based process
0.33	GO:0007010	cytoskeleton organization

0.53	GO:0016491	oxidoreductase activity
0.33	GO:0005200	structural constituent of cytoskeleton
0.32	GO:0003924	GTPase activity
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.36	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0005576	extracellular region
0.33	GO:0005874	microtubule
0.30	GO:0031224	intrinsic component of membrane

0.53

GO:0016491

tr|T1FWI1|T1FWI1_HELRO
Uncharacterized protein
Search

tr|T1FWI2|T1FWI2_HELRO
Uncharacterized protein
Search

PNO1

0.85	Partner of NOB1 homolog

0.59

GO:0003723

RNA binding

0.62

GO:0005730

nucleolus

tr|T1FWI3|T1FWI3_HELRO
Uncharacterized protein
Search

0.53	Ferrous iron transporter B

0.47	GO:0010077	maintenance of inflorescence meristem identity
0.46	GO:0048825	cotyledon development
0.45	GO:2000024	regulation of leaf development
0.45	GO:0048444	floral organ morphogenesis
0.45	GO:0045604	regulation of epidermal cell differentiation
0.44	GO:0045995	regulation of embryonic development
0.41	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
0.41	GO:0045934	negative regulation of nucleobase-containing compound metabolic process
0.41	GO:0042254	ribosome biogenesis
0.40	GO:0010629	negative regulation of gene expression

0.66	GO:0005525	GTP binding
0.43	GO:0003924	GTPase activity
0.35	GO:0048027	mRNA 5'-UTR binding
0.33	GO:0004222	metalloendopeptidase activity
0.33	GO:0004672	protein kinase activity
0.32	GO:0046872	metal ion binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0008144	drug binding

0.47	GO:0005730	nucleolus
0.43	GO:0055044	symplast
0.42	GO:0005911	cell-cell junction
0.37	GO:0005654	nucleoplasm
0.35	GO:0005697	telomerase holoenzyme complex
0.34	GO:0005829	cytosol
0.33	GO:0005739	mitochondrion
0.33	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.33

GO:0004222

tr|T1FWI4|T1FWI4_HELRO
Uncharacterized protein
Search

tr|T1FWI5|T1FWI5_HELRO
Uncharacterized protein
Search

tr|T1FWI6|T1FWI6_HELRO
alpha-1,2-Mannosidase
Search

0.24	alpha-1,2-Mannosidase

0.52	GO:0097466	ubiquitin-dependent glycoprotein ERAD pathway
0.48	GO:0036509	trimming of terminal mannose on B branch
0.48	GO:1904154	positive regulation of retrograde protein transport, ER to cytosol
0.47	GO:0035977	protein deglycosylation involved in glycoprotein catabolic process
0.44	GO:0006491	N-glycan processing
0.44	GO:0030968	endoplasmic reticulum unfolded protein response

0.82	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
0.70	GO:0005509	calcium ion binding

0.47	GO:0044322	endoplasmic reticulum quality control compartment
0.30	GO:0031224	intrinsic component of membrane

0.82	EC:3.2.1.113	GO:0004571
0.82	KEGG:R05982 KEGG:R06722	GO:0004571

tr|T1FWI7|T1FWI7_HELRO
Uncharacterized protein
Search

0.45	GO:0018108	peptidyl-tyrosine phosphorylation
0.44	GO:0000186	activation of MAPKK activity
0.43	GO:0007155	cell adhesion
0.43	GO:0000165	MAPK cascade
0.41	GO:0006508	proteolysis
0.40	GO:0006910	phagocytosis, recognition
0.40	GO:0050766	positive regulation of phagocytosis
0.40	GO:0010811	positive regulation of cell-substrate adhesion
0.40	GO:0050830	defense response to Gram-positive bacterium
0.39	GO:0006898	receptor-mediated endocytosis

0.45	GO:0005509	calcium ion binding
0.45	GO:0140096	catalytic activity, acting on a protein
0.44	GO:0016301	kinase activity
0.44	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.42	GO:0005057	signal transducer activity, downstream of receptor
0.41	GO:0005044	scavenger receptor activity
0.41	GO:0097367	carbohydrate derivative binding
0.41	GO:0030554	adenyl nucleotide binding
0.40	GO:0008144	drug binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding

0.41	GO:0005578	proteinaceous extracellular matrix
0.40	GO:0044420	extracellular matrix component
0.38	GO:0009986	cell surface
0.34	GO:0005622	intracellular
0.30	GO:0016020	membrane

0.44

GO:0016773

tr|T1FWI8|T1FWI8_HELRO
Uncharacterized protein
Search

tr|T1FWI9|T1FWI9_HELRO
Uncharacterized protein
Search

tr|T1FWJ0|T1FWJ0_HELRO
Uncharacterized protein
Search

tr|T1FWJ1|T1FWJ1_HELRO
Uncharacterized protein
Search

tr|T1FWJ2|T1FWJ2_HELRO
Uncharacterized protein
Search

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.40	GO:1901045	negative regulation of oviposition
0.36	GO:0008345	larval locomotory behavior
0.35	GO:0002209	behavioral defense response
0.35	GO:0008344	adult locomotory behavior
0.33	GO:0035556	intracellular signal transduction

0.78

GO:0008528

G-protein coupled peptide receptor activity

0.34	GO:0005887	integral component of plasma membrane
0.32	GO:0005622	intracellular

tr|T1FWJ3|T1FWJ3_HELRO
Uncharacterized protein
Search

tr|T1FWJ4|T1FWJ4_HELRO
Uncharacterized protein
Search

0.21	Short-chain dehydrogenase

0.51	GO:0055114	oxidation-reduction process
0.45	GO:0006621	protein retention in ER lumen
0.41	GO:0019290	siderophore biosynthetic process
0.37	GO:0006629	lipid metabolic process

0.52	GO:0016491	oxidoreductase activity
0.46	GO:0004312	fatty acid synthase activity
0.45	GO:0046923	ER retention sequence binding
0.39	GO:0008374	O-acyltransferase activity

0.41	GO:0005783	endoplasmic reticulum
0.30	GO:0016020	membrane

0.52

GO:0016491

tr|T1FWJ5|T1FWJ5_HELRO
Uncharacterized protein
Search

tr|T1FWJ6|T1FWJ6_HELRO
Uncharacterized protein
Search

0.75	GO:0006338	chromatin remodeling
0.38	GO:0007305	vitelline membrane formation involved in chorion-containing eggshell formation
0.38	GO:2001141	regulation of RNA biosynthetic process
0.38	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.38	GO:0040029	regulation of gene expression, epigenetic
0.38	GO:0007306	eggshell chorion assembly
0.38	GO:0007480	imaginal disc-derived leg morphogenesis
0.37	GO:1905268	negative regulation of chromatin organization
0.37	GO:0060969	negative regulation of gene silencing
0.37	GO:0051253	negative regulation of RNA metabolic process

0.72	GO:0003682	chromatin binding
0.51	GO:0003677	DNA binding
0.46	GO:0042393	histone binding
0.41	GO:0140030	modification-dependent protein binding
0.37	GO:0030554	adenyl nucleotide binding
0.37	GO:0097367	carbohydrate derivative binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0015616	DNA translocase activity
0.35	GO:0046872	metal ion binding

0.80	GO:0016586	RSC-type complex
0.40	GO:0016589	NURF complex
0.38	GO:0035060	brahma complex
0.37	GO:0005700	polytene chromosome
0.36	GO:0016514	SWI/SNF complex
0.35	GO:0000775	chromosome, centromeric region
0.34	GO:0017119	Golgi transport complex
0.33	GO:0046695	SLIK (SAGA-like) complex
0.33	GO:0000124	SAGA complex
0.30	GO:0016020	membrane

0.33

EC:3.4.25

GO:0004298

tr|T1FWJ7|T1FWJ7_HELRO
Uncharacterized protein
Search

tr|T1FWJ8|T1FWJ8_HELRO
Uncharacterized protein
Search

RPS14

0.63	Ribosomal protein S14

0.57	GO:0043043	peptide biosynthetic process
0.53	GO:0044267	cellular protein metabolic process
0.51	GO:0010467	gene expression
0.50	GO:0030218	erythrocyte differentiation
0.50	GO:0009059	macromolecule biosynthetic process
0.47	GO:0000028	ribosomal small subunit assembly
0.44	GO:0000122	negative regulation of transcription by RNA polymerase II
0.43	GO:0061515	myeloid cell development
0.43	GO:0071695	anatomical structure maturation
0.42	GO:0048469	cell maturation

0.60	GO:0003735	structural constituent of ribosome
0.46	GO:0048027	mRNA 5'-UTR binding
0.45	GO:0045182	translation regulator activity
0.42	GO:0070181	small ribosomal subunit rRNA binding
0.35	GO:0042289	MHC class II protein binding

0.58	GO:0005840	ribosome
0.44	GO:0044445	cytosolic part
0.43	GO:0005730	nucleolus
0.39	GO:0005739	mitochondrion
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.35	GO:0031012	extracellular matrix
0.33	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1FWJ9|T1FWJ9_HELRO
Uncharacterized protein
Search

0.65	GO:0003062	regulation of heart rate by chemical signal
0.63	GO:0060307	regulation of ventricular cardiac muscle cell membrane repolarization
0.52	GO:0046662	regulation of oviposition
0.51	GO:0046716	muscle cell cellular homeostasis
0.51	GO:0045214	sarcomere organization
0.49	GO:0007626	locomotory behavior
0.49	GO:0040017	positive regulation of locomotion
0.46	GO:0006468	protein phosphorylation
0.39	GO:0050790	regulation of catalytic activity
0.38	GO:0051716	cellular response to stimulus

0.51	GO:0008307	structural constituent of muscle
0.50	GO:0008641	ubiquitin-like modifier activating enzyme activity
0.50	GO:0050998	nitric-oxide synthase binding
0.46	GO:0004672	protein kinase activity
0.44	GO:0030235	nitric-oxide synthase regulator activity
0.42	GO:0017049	GTP-Rho binding
0.41	GO:0032559	adenyl ribonucleotide binding
0.41	GO:0008144	drug binding
0.41	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0003676	nucleic acid binding

0.55	GO:0044449	contractile fiber part
0.50	GO:0016010	dystrophin-associated glycoprotein complex
0.49	GO:0030315	T-tubule
0.49	GO:0030424	axon
0.48	GO:0033017	sarcoplasmic reticulum membrane
0.47	GO:0005901	caveola
0.46	GO:0030016	myofibril
0.40	GO:0005739	mitochondrion
0.38	GO:0032783	ELL-EAF complex
0.37	GO:0020011	apicoplast

0.38	EC:3.2.1	GO:0004553
0.36	KEGG:R03876	GO:0004842

tr|T1FWK0|T1FWK0_HELRO
Uncharacterized protein
Search

tr|T1FWK1|T1FWK1_HELRO
Uncharacterized protein
Search

0.53	GO:0055114	oxidation-reduction process
0.33	GO:0035023	regulation of Rho protein signal transduction
0.32	GO:0065009	regulation of molecular function

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.65	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.33	GO:0005089	Rho guanyl-nucleotide exchange factor activity

0.33	GO:0005789	endoplasmic reticulum membrane
0.32	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

tr|T1FWK2|T1FWK2_HELRO
Uncharacterized protein
Search

tr|T1FWK3|T1FWK3_HELRO
Uncharacterized protein
Search

tr|T1FWK4|T1FWK4_HELRO
Uncharacterized protein
Search

tr|T1FWK5|T1FWK5_HELRO
Uncharacterized protein
Search

tr|T1FWK6|T1FWK6_HELRO
Receptor expression-enhancing protein
Search

0.37	Receptor expression-enhancing protein

0.48	GO:0034976	response to endoplasmic reticulum stress
0.37	GO:0006997	nucleus organization
0.37	GO:0010256	endomembrane system organization
0.35	GO:1903047	mitotic cell cycle process
0.35	GO:0061024	membrane organization
0.35	GO:0032581	ER-dependent peroxisome organization
0.34	GO:0046931	pore complex assembly
0.34	GO:0048308	organelle inheritance
0.33	GO:0043623	cellular protein complex assembly
0.33	GO:0016192	vesicle-mediated transport

0.45	GO:0005783	endoplasmic reticulum
0.34	GO:0044448	cell cortex part
0.33	GO:0032153	cell division site
0.33	GO:0031984	organelle subcompartment
0.30	GO:0044425	membrane part

tr|T1FWK7|T1FWK7_HELRO
Peptidylprolyl isomerase
Search

0.15	Peptidylprolyl isomerase

0.71	GO:0000413	protein peptidyl-prolyl isomerization
0.46	GO:0006457	protein folding
0.35	GO:0044691	tooth eruption
0.35	GO:0070166	enamel mineralization
0.35	GO:0016310	phosphorylation
0.34	GO:0016570	histone modification
0.34	GO:0071902	positive regulation of protein serine/threonine kinase activity
0.34	GO:0055074	calcium ion homeostasis

0.71	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.42	GO:0005528	FK506 binding
0.42	GO:0005509	calcium ion binding
0.36	GO:0004674	protein serine/threonine kinase activity
0.34	GO:0043539	protein serine/threonine kinase activator activity

0.35	GO:0005783	endoplasmic reticulum
0.34	GO:0005615	extracellular space
0.33	GO:0005794	Golgi apparatus
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0031984	organelle subcompartment
0.33	GO:0098796	membrane protein complex
0.33	GO:0005730	nucleolus
0.30	GO:0016021	integral component of membrane

0.71

GO:0003755

tr|T1FWK8|T1FWK8_HELRO
Uncharacterized protein
Search

0.35	GO:0035335	peptidyl-tyrosine dephosphorylation
0.34	GO:0044355	clearance of foreign intracellular DNA
0.34	GO:0006304	DNA modification
0.34	GO:0032485	regulation of Ral protein signal transduction
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0080090	regulation of primary metabolic process
0.33	GO:0010468	regulation of gene expression
0.33	GO:0051171	regulation of nitrogen compound metabolic process
0.33	GO:0000272	polysaccharide catabolic process
0.33	GO:0090071	negative regulation of ribosome biogenesis

0.74	GO:0005543	phospholipid binding
0.54	GO:0003779	actin binding
0.35	GO:0004725	protein tyrosine phosphatase activity
0.33	GO:0004519	endonuclease activity
0.33	GO:0098772	molecular function regulator
0.33	GO:0005509	calcium ion binding
0.33	GO:0030246	carbohydrate binding
0.33	GO:0016772	transferase activity, transferring phosphorus-containing groups
0.33	GO:0003677	DNA binding
0.33	GO:0051020	GTPase binding

0.34	GO:0005730	nucleolus
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.35

GO:0004725

tr|T1FWK9|T1FWK9_HELRO
Uncharacterized protein
Search

0.72	GO:0042325	regulation of phosphorylation
0.35	GO:0006418	tRNA aminoacylation for protein translation
0.35	GO:0043486	histone exchange
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.35	GO:0016875	ligase activity, forming carbon-oxygen bonds
0.35	GO:0140101	catalytic activity, acting on a tRNA
0.34	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.49	GO:0005737	cytoplasm
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.35

EC:6.1

GO:0016875

tr|T1FWL0|T1FWL0_HELRO
Uncharacterized protein
Search

0.55	GO:0007165	signal transduction
0.55	GO:0034220	ion transmembrane transport
0.42	GO:0031285	regulation of sorocarp stalk cell differentiation
0.42	GO:1901261	regulation of sorocarp spore cell differentiation
0.41	GO:0030708	germarium-derived female germ-line cyst encapsulation
0.41	GO:0035317	imaginal disc-derived wing hair organization
0.40	GO:0051173	positive regulation of nitrogen compound metabolic process
0.40	GO:0010604	positive regulation of macromolecule metabolic process
0.40	GO:0097320	plasma membrane tubulation
0.40	GO:0031325	positive regulation of cellular metabolic process

0.67	GO:0005230	extracellular ligand-gated ion channel activity
0.62	GO:0004888	transmembrane signaling receptor activity
0.41	GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential
0.39	GO:0022835	transmitter-gated channel activity
0.39	GO:0140135	mechanosensitive cation channel activity
0.39	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.38	GO:0005096	GTPase activator activity
0.38	GO:0008289	lipid binding
0.37	GO:0004674	protein serine/threonine kinase activity
0.37	GO:0046983	protein dimerization activity

0.40	GO:0045211	postsynaptic membrane
0.39	GO:0030054	cell junction
0.38	GO:0005768	endosome
0.36	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.37

GO:0004674

tr|T1FWL1|T1FWL1_HELRO
Uncharacterized protein
Search

0.57	GO:0007186	G-protein coupled receptor signaling pathway
0.42	GO:0099139	cheating during chimeric sorocarp development
0.40	GO:0034968	histone lysine methylation
0.39	GO:0006836	neurotransmitter transport
0.38	GO:0060255	regulation of macromolecule metabolic process
0.38	GO:0007155	cell adhesion
0.38	GO:0065009	regulation of molecular function
0.38	GO:0035023	regulation of Rho protein signal transduction
0.37	GO:0055085	transmembrane transport
0.37	GO:0007018	microtubule-based movement

0.58	GO:0004930	G-protein coupled receptor activity
0.41	GO:0018024	histone-lysine N-methyltransferase activity
0.39	GO:0022804	active transmembrane transporter activity
0.39	GO:0005515	protein binding
0.39	GO:0005326	neurotransmitter transporter activity
0.39	GO:0016462	pyrophosphatase activity
0.39	GO:0098772	molecular function regulator
0.38	GO:0032559	adenyl ribonucleotide binding
0.38	GO:0046872	metal ion binding
0.38	GO:0015081	sodium ion transmembrane transporter activity

0.41	GO:0005634	nucleus
0.40	GO:0005667	transcription factor complex
0.36	GO:0005618	cell wall
0.35	GO:0019867	outer membrane
0.35	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.41	EC:2.1.1.43	GO:0018024
0.36	KEGG:R03876	GO:0004842

tr|T1FWL2|T1FWL2_HELRO
Uncharacterized protein
Search

tr|T1FWL3|T1FWL3_HELRO
Uncharacterized protein
Search

tr|T1FWL4|T1FWL4_HELRO
Uncharacterized protein
Search

0.80	Lipid phosphate phosphohydrolase 3

0.63	GO:0030111	regulation of Wnt signaling pathway
0.62	GO:0016311	dephosphorylation
0.57	GO:0006629	lipid metabolic process
0.53	GO:1902068	regulation of sphingolipid mediated signaling pathway
0.52	GO:0060020	Bergmann glial cell differentiation
0.50	GO:0001702	gastrulation with mouth forming second
0.50	GO:0060070	canonical Wnt signaling pathway
0.49	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
0.49	GO:0051091	positive regulation of DNA binding transcription factor activity
0.48	GO:0019637	organophosphate metabolic process

0.71	GO:0042577	lipid phosphatase activity
0.61	GO:0008195	phosphatidate phosphatase activity
0.54	GO:0042392	sphingosine-1-phosphate phosphatase activity
0.50	GO:0005178	integrin binding
0.35	GO:0005319	lipid transporter activity
0.33	GO:0004721	phosphoprotein phosphatase activity

0.46	GO:0005886	plasma membrane
0.40	GO:0005918	septate junction
0.40	GO:0045177	apical part of cell
0.37	GO:0070062	extracellular exosome
0.36	GO:0012505	endomembrane system
0.35	GO:0031984	organelle subcompartment
0.34	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0044444	cytoplasmic part
0.34	GO:0005912	adherens junction
0.30	GO:0016021	integral component of membrane

0.61

EC:3.1.3.4

GO:0008195

tr|T1FWL5|T1FWL5_HELRO
Uncharacterized protein
Search

0.46	GO:0006913	nucleocytoplasmic transport
0.45	GO:1902877	positive regulation of embryonic pattern specification
0.44	GO:0014881	regulation of myofibril size
0.44	GO:1904582	positive regulation of intracellular mRNA localization
0.44	GO:0071689	muscle thin filament assembly
0.44	GO:0007279	pole cell formation
0.44	GO:0060282	positive regulation of oocyte development
0.44	GO:1903431	positive regulation of cell maturation
0.44	GO:0007317	regulation of pole plasm oskar mRNA localization
0.43	GO:0007291	sperm individualization

0.43	GO:0046872	metal ion binding
0.42	GO:0003779	actin binding
0.39	GO:0008140	cAMP response element binding protein binding
0.39	GO:0017056	structural constituent of nuclear pore
0.38	GO:0008677	2-dehydropantoate 2-reductase activity
0.38	GO:0003676	nucleic acid binding
0.36	GO:0003887	DNA-directed DNA polymerase activity
0.36	GO:0004674	protein serine/threonine kinase activity
0.35	GO:0016746	transferase activity, transferring acyl groups
0.34	GO:0032559	adenyl ribonucleotide binding

0.48	GO:0005643	nuclear pore
0.44	GO:0070864	sperm individualization complex
0.43	GO:0031672	A band
0.42	GO:0030018	Z disc
0.42	GO:0005925	focal adhesion
0.30	GO:0031224	intrinsic component of membrane

0.38	EC:1.1.1.169	GO:0008677
0.38	KEGG:R02472	GO:0008677

tr|T1FWL6|T1FWL6_HELRO
Uncharacterized protein
Search

ZFAND5A

0.72	AN1-type zinc finger protein 6

0.50	GO:0010761	fibroblast migration
0.50	GO:0003016	respiratory system process
0.50	GO:0048745	smooth muscle tissue development
0.49	GO:0048008	platelet-derived growth factor receptor signaling pathway
0.49	GO:0060324	face development
0.47	GO:0048705	skeletal system morphogenesis
0.47	GO:0001944	vasculature development
0.46	GO:0001701	in utero embryonic development

0.63	GO:0008270	zinc ion binding
0.54	GO:0003677	DNA binding
0.35	GO:0019904	protein domain specific binding

0.32	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

tr|T1FWL7|T1FWL7_HELRO
Uncharacterized protein
Search

tr|T1FWL8|T1FWL8_HELRO
Uncharacterized protein
Search

0.36	GO:0007155	cell adhesion
0.36	GO:0007219	Notch signaling pathway
0.35	GO:0030154	cell differentiation
0.34	GO:0050793	regulation of developmental process

0.68	GO:0005509	calcium ion binding
0.45	GO:0005201	extracellular matrix structural constituent
0.38	GO:0003682	chromatin binding

0.44	GO:0044421	extracellular region part
0.36	GO:0005581	collagen trimer
0.33	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

tr|T1FWL9|T1FWL9_HELRO
Uncharacterized protein
Search

tr|T1FWM0|T1FWM0_HELRO
Uncharacterized protein
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tr|T1FWM1|T1FWM1_HELRO
Uncharacterized protein
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0.57	GO:0009107	lipoate biosynthetic process
0.55	GO:0009249	protein lipoylation
0.49	GO:0017182	peptidyl-diphthamide metabolic process
0.49	GO:1900247	regulation of cytoplasmic translational elongation
0.45	GO:0006468	protein phosphorylation
0.42	GO:0032259	methylation

0.57	GO:0016992	lipoate synthase activity
0.50	GO:0051539	4 iron, 4 sulfur cluster binding
0.50	GO:0004164	diphthine synthase activity
0.45	GO:0004672	protein kinase activity
0.43	GO:0046872	metal ion binding
0.41	GO:0032559	adenyl ribonucleotide binding
0.41	GO:0008144	drug binding
0.41	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0003676	nucleic acid binding

0.61	GO:0020011	apicoplast
0.30	GO:0016020	membrane

0.57

EC:2.8.1.8

GO:0016992

tr|T1FWM2|T1FWM2_HELRO
Uncharacterized protein
Search

tr|T1FWM3|T1FWM3_HELRO
Uncharacterized protein
Search

tr|T1FWM4|T1FWM4_HELRO
Uncharacterized protein
Search

0.60	GO:0006468	protein phosphorylation
0.53	GO:0018209	peptidyl-serine modification
0.53	GO:1900181	negative regulation of protein localization to nucleus
0.52	GO:0035556	intracellular signal transduction
0.48	GO:0018210	peptidyl-threonine modification
0.41	GO:0070727	cellular macromolecule localization
0.41	GO:0046907	intracellular transport
0.40	GO:0015031	protein transport
0.39	GO:0033750	ribosome localization
0.39	GO:0071166	ribonucleoprotein complex localization

0.60	GO:0004672	protein kinase activity
0.52	GO:0030554	adenyl nucleotide binding
0.51	GO:0097367	carbohydrate derivative binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0008144	drug binding
0.41	GO:0008536	Ran GTPase binding
0.37	GO:0005516	calmodulin binding
0.33	GO:0043565	sequence-specific DNA binding
0.33	GO:0019001	guanyl nucleotide binding
0.33	GO:0016787	hydrolase activity

0.46	GO:0005634	nucleus
0.39	GO:0005737	cytoplasm
0.37	GO:1990234	transferase complex
0.34	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part
0.33	GO:0012505	endomembrane system
0.32	GO:0043234	protein complex
0.32	GO:0031975	envelope
0.30	GO:0016020	membrane

0.33	EC:3	GO:0016787
0.32	KEGG:R03876	GO:0004842

tr|T1FWM5|T1FWM5_HELRO
Uncharacterized protein
Search

0.48	GO:0051568	histone H3-K4 methylation
0.45	GO:0055085	transmembrane transport
0.43	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway
0.43	GO:0045893	positive regulation of transcription, DNA-templated
0.42	GO:0043627	response to estrogen
0.42	GO:0006357	regulation of transcription by RNA polymerase II
0.41	GO:0008284	positive regulation of cell proliferation
0.40	GO:0048268	clathrin coat assembly
0.40	GO:0048699	generation of neurons
0.40	GO:0009880	embryonic pattern specification

0.49	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.46	GO:0005215	transporter activity
0.43	GO:0044212	transcription regulatory region DNA binding
0.43	GO:0005515	protein binding
0.41	GO:0005545	1-phosphatidylinositol binding
0.40	GO:0046872	metal ion binding
0.38	GO:1990837	sequence-specific double-stranded DNA binding
0.38	GO:0140110	transcription regulator activity
0.37	GO:0005096	GTPase activator activity
0.35	GO:0050825	ice binding

0.47	GO:0035097	histone methyltransferase complex
0.40	GO:0030136	clathrin-coated vesicle
0.37	GO:0000228	nuclear chromosome
0.36	GO:0000124	SAGA complex
0.36	GO:0000785	chromatin
0.35	GO:0030173	integral component of Golgi membrane
0.35	GO:1904949	ATPase complex
0.35	GO:0046695	SLIK (SAGA-like) complex
0.34	GO:0005669	transcription factor TFIID complex
0.34	GO:0005886	plasma membrane

0.35

GO:0016773

tr|T1FWM6|T1FWM6_HELRO
Uncharacterized protein
Search

0.45	GO:0045162	clustering of voltage-gated sodium channels
0.44	GO:0035023	regulation of Rho protein signal transduction
0.44	GO:0098870	action potential propagation
0.43	GO:0001525	angiogenesis
0.43	GO:0034113	heterotypic cell-cell adhesion
0.43	GO:0031290	retinal ganglion cell axon guidance
0.42	GO:0019226	transmission of nerve impulse
0.42	GO:0050767	regulation of neurogenesis
0.42	GO:0006468	protein phosphorylation
0.41	GO:0120035	regulation of plasma membrane bounded cell projection organization

0.45	GO:0030506	ankyrin binding
0.44	GO:0086080	protein binding involved in heterotypic cell-cell adhesion
0.44	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.42	GO:0004672	protein kinase activity
0.41	GO:0005509	calcium ion binding
0.38	GO:0030554	adenyl nucleotide binding
0.38	GO:0032555	purine ribonucleotide binding
0.38	GO:0008144	drug binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0004601	peroxidase activity

0.41	GO:0030424	axon
0.40	GO:0045202	synapse
0.38	GO:0005576	extracellular region
0.36	GO:0071944	cell periphery
0.35	GO:0099568	cytoplasmic region
0.35	GO:0030054	cell junction
0.34	GO:0120038	plasma membrane bounded cell projection part
0.30	GO:0016020	membrane

0.37	EC:1.11.1.7	GO:0004601
0.37	KEGG:R03532	GO:0004601

tr|T1FWM7|T1FWM7_HELRO
Uncharacterized protein
Search

tr|T1FWM8|T1FWM8_HELRO
Uncharacterized protein
Search

0.42	GO:0000956	nuclear-transcribed mRNA catabolic process
0.38	GO:0006396	RNA processing

0.36

GO:0005515

protein binding

0.85	GO:0055087	Ski complex
0.83	GO:0035327	transcriptionally active chromatin
0.67	GO:0005654	nucleoplasm
0.66	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

tr|T1FWM9|T1FWM9_HELRO
Uncharacterized protein
Search

0.42	GO:0008643	carbohydrate transport
0.41	GO:0036211	protein modification process
0.40	GO:0065007	biological regulation
0.40	GO:0044267	cellular protein metabolic process
0.39	GO:0016310	phosphorylation
0.39	GO:0006401	RNA catabolic process
0.38	GO:0016071	mRNA metabolic process
0.37	GO:0032502	developmental process
0.37	GO:0071840	cellular component organization or biogenesis
0.37	GO:0051716	cellular response to stimulus

0.41	GO:0004674	protein serine/threonine kinase activity
0.40	GO:0046872	metal ion binding
0.39	GO:0003676	nucleic acid binding
0.39	GO:0008047	enzyme activator activity
0.38	GO:0030554	adenyl nucleotide binding
0.38	GO:0032555	purine ribonucleotide binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0008144	drug binding
0.37	GO:0004842	ubiquitin-protein transferase activity
0.37	GO:0140110	transcription regulator activity

0.43	GO:0005634	nucleus
0.38	GO:0032991	macromolecular complex
0.36	GO:0070013	intracellular organelle lumen
0.36	GO:0044444	cytoplasmic part
0.35	GO:0044446	intracellular organelle part
0.35	GO:0043232	intracellular non-membrane-bounded organelle
0.34	GO:0005912	adherens junction
0.34	GO:0020036	Maurer's cleft
0.33	GO:0012505	endomembrane system
0.33	GO:0048475	coated membrane

0.41	EC:2.7.11	GO:0004674
0.37	KEGG:R03876	GO:0004842

tr|T1FWN0|T1FWN0_HELRO
Uncharacterized protein
Search

tr|T1FWN1|T1FWN1_HELRO
Uncharacterized protein
Search

tr|T1FWN2|T1FWN2_HELRO
Uncharacterized protein
Search

0.60	GO:0005975	carbohydrate metabolic process
0.34	GO:0060271	cilium assembly

0.75

GO:0004565

beta-galactosidase activity

0.38	GO:0005773	vacuole
0.35	GO:0097546	ciliary base
0.30	GO:0031224	intrinsic component of membrane

0.75

EC:3.2.1.23

GO:0004565

tr|T1FWN3|T1FWN3_HELRO
Uncharacterized protein
Search

0.10	Galactosidase beta 1 like 3

0.60	GO:0005975	carbohydrate metabolic process
0.34	GO:0060271	cilium assembly

0.76

GO:0004565

beta-galactosidase activity

0.41	GO:0005773	vacuole
0.35	GO:0097546	ciliary base
0.33	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.76

EC:3.2.1.23

GO:0004565

tr|T1FWN4|T1FWN4_HELRO
Uncharacterized protein
Search

0.89	Pre-B-cell leukemia transcription factor

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.46	GO:0001654	eye development
0.46	GO:0061061	muscle structure development
0.46	GO:0007420	brain development
0.44	GO:0048468	cell development
0.44	GO:0001742	oenocyte differentiation
0.43	GO:0000060	protein import into nucleus, translocation
0.43	GO:0042659	regulation of cell fate specification

0.63	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.42	GO:0033613	activating transcription factor binding
0.42	GO:0035326	enhancer binding
0.41	GO:0003713	transcription coactivator activity
0.40	GO:0046982	protein heterodimerization activity

0.61	GO:0005634	nucleus
0.40	GO:0005667	transcription factor complex
0.39	GO:0032993	protein-DNA complex
0.34	GO:0005737	cytoplasm
0.34	GO:0001741	XY body
0.30	GO:0016020	membrane

tr|T1FWN5|T1FWN5_HELRO
Uncharacterized protein
Search

tr|T1FWN6|T1FWN6_HELRO
Uncharacterized protein
Search

0.44	GO:0060255	regulation of macromolecule metabolic process
0.43	GO:0031326	regulation of cellular biosynthetic process
0.43	GO:0051171	regulation of nitrogen compound metabolic process
0.43	GO:0080090	regulation of primary metabolic process
0.41	GO:0006468	protein phosphorylation
0.40	GO:0016070	RNA metabolic process
0.40	GO:0007458	progression of morphogenetic furrow involved in compound eye morphogenesis
0.40	GO:0007264	small GTPase mediated signal transduction
0.40	GO:0010467	gene expression
0.39	GO:0035332	positive regulation of hippo signaling

0.45	GO:0008270	zinc ion binding
0.45	GO:0016874	ligase activity
0.43	GO:0140110	transcription regulator activity
0.43	GO:0003676	nucleic acid binding
0.42	GO:0017076	purine nucleotide binding
0.42	GO:0097367	carbohydrate derivative binding
0.42	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0005515	protein binding
0.42	GO:0008144	drug binding
0.41	GO:0004672	protein kinase activity

0.46	GO:0005634	nucleus
0.40	GO:0036464	cytoplasmic ribonucleoprotein granule
0.39	GO:0005703	polytene chromosome puff
0.39	GO:0005667	transcription factor complex
0.38	GO:0000131	incipient cellular bud site
0.38	GO:0005934	cellular bud tip
0.38	GO:0043332	mating projection tip
0.38	GO:0005935	cellular bud neck
0.37	GO:0034708	methyltransferase complex
0.37	GO:0005938	cell cortex

0.45

GO:0016874

tr|T1FWN7|T1FWN7_HELRO
Uncharacterized protein
Search

0.61

GO:0007165

signal transduction

tr|T1FWN8|T1FWN8_HELRO
Uncharacterized protein
Search

tr|T1FWN9|T1FWN9_HELRO
Uncharacterized protein
Search

0.77	GO:0007264	small GTPase mediated signal transduction
0.66	GO:0065009	regulation of molecular function

0.75	GO:0005085	guanyl-nucleotide exchange factor activity
0.53	GO:0017160	Ral GTPase binding
0.46	GO:0030695	GTPase regulator activity

0.49	GO:0005903	brush border
0.45	GO:0005622	intracellular
0.39	GO:0043227	membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

tr|T1FWP0|T1FWP0_HELRO
Uncharacterized protein
Search

0.57	GO:0043044	ATP-dependent chromatin remodeling
0.51	GO:0035278	miRNA mediated inhibition of translation
0.41	GO:0055114	oxidation-reduction process
0.38	GO:0016570	histone modification
0.37	GO:0005975	carbohydrate metabolic process
0.37	GO:0006482	protein demethylation
0.37	GO:0006032	chitin catabolic process
0.37	GO:0016998	cell wall macromolecule catabolic process
0.37	GO:0007165	signal transduction
0.36	GO:1903506	regulation of nucleic acid-templated transcription

0.45	GO:0032559	adenyl ribonucleotide binding
0.44	GO:0008144	drug binding
0.44	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0046872	metal ion binding
0.42	GO:0016491	oxidoreductase activity
0.40	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.38	GO:0003676	nucleic acid binding
0.38	GO:0050825	ice binding
0.38	GO:0032452	histone demethylase activity
0.37	GO:0003700	DNA binding transcription factor activity

0.40	GO:0005911	cell-cell junction
0.39	GO:0005634	nucleus
0.37	GO:0009277	fungal-type cell wall
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0044446	intracellular organelle part
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.42

GO:0016491

tr|T1FWP1|T1FWP1_HELRO
Uncharacterized protein
Search

0.46	GO:2001141	regulation of RNA biosynthetic process
0.46	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.46	GO:0010468	regulation of gene expression
0.37	GO:0016192	vesicle-mediated transport
0.36	GO:0016482	cytosolic transport
0.36	GO:0016197	endosomal transport
0.36	GO:0010587	miRNA catabolic process
0.36	GO:0010467	gene expression
0.36	GO:0033043	regulation of organelle organization
0.35	GO:0009059	macromolecule biosynthetic process

0.47	GO:0003676	nucleic acid binding
0.39	GO:0140110	transcription regulator activity
0.38	GO:0005515	protein binding
0.36	GO:0046872	metal ion binding
0.36	GO:0031386	protein tag
0.36	GO:0000285	1-phosphatidylinositol-3-phosphate 5-kinase activity
0.35	GO:0017056	structural constituent of nuclear pore
0.35	GO:0140098	catalytic activity, acting on RNA
0.35	GO:1901265	nucleoside phosphate binding
0.34	GO:0016849	phosphorus-oxygen lyase activity

0.46	GO:0005634	nucleus
0.37	GO:0044446	intracellular organelle part
0.36	GO:0043234	protein complex
0.36	GO:0070013	intracellular organelle lumen
0.36	GO:0000313	organellar ribosome
0.36	GO:0012505	endomembrane system
0.35	GO:0098588	bounding membrane of organelle
0.35	GO:0005829	cytosol
0.35	GO:0005739	mitochondrion
0.34	GO:0031410	cytoplasmic vesicle

0.36	EC:2.7.1.150	GO:0000285
0.36	KEGG:R05802	GO:0000285

tr|T1FWP2|T1FWP2_HELRO
Uncharacterized protein
Search

0.10	Solute carrier family 23 member 2

0.85	GO:0015882	L-ascorbic acid transport
0.57	GO:0070633	transepithelial transport
0.55	GO:0055085	transmembrane transport
0.55	GO:0070837	dehydroascorbic acid transport
0.50	GO:0030324	lung development
0.49	GO:0007420	brain development
0.47	GO:0006814	sodium ion transport
0.45	GO:0009636	response to toxic substance
0.37	GO:0019852	L-ascorbic acid metabolic process
0.34	GO:0006979	response to oxidative stress

0.85	GO:0070890	sodium-dependent L-ascorbate transmembrane transporter activity
0.60	GO:0008520	L-ascorbate:sodium symporter activity
0.55	GO:0033300	dehydroascorbic acid transmembrane transporter activity
0.34	GO:0015205	nucleobase transmembrane transporter activity
0.33	GO:0005515	protein binding

0.56	GO:0009925	basal plasma membrane
0.54	GO:0016324	apical plasma membrane
0.39	GO:0043229	intracellular organelle
0.39	GO:0005737	cytoplasm
0.35	GO:0005887	integral component of plasma membrane
0.35	GO:0070062	extracellular exosome
0.34	GO:0005903	brush border

tr|T1FWP3|T1FWP3_HELRO
Uncharacterized protein
Search

tr|T1FWP4|T1FWP4_HELRO
Uncharacterized protein
Search

0.41	GO:0006030	chitin metabolic process
0.38	GO:0036211	protein modification process
0.37	GO:0016311	dephosphorylation
0.37	GO:0044267	cellular protein metabolic process
0.37	GO:0006508	proteolysis
0.36	GO:0055114	oxidation-reduction process
0.36	GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
0.35	GO:0005975	carbohydrate metabolic process
0.35	GO:0007018	microtubule-based movement
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.41	GO:0008061	chitin binding
0.39	GO:0140096	catalytic activity, acting on a protein
0.38	GO:0003676	nucleic acid binding
0.38	GO:0042578	phosphoric ester hydrolase activity
0.37	GO:0046872	metal ion binding
0.36	GO:0016491	oxidoreductase activity
0.36	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.35	GO:0003777	microtubule motor activity
0.35	GO:0008017	microtubule binding
0.35	GO:0017171	serine hydrolase activity

0.40	GO:0005576	extracellular region
0.35	GO:0005634	nucleus
0.35	GO:1990234	transferase complex
0.34	GO:0030015	CCR4-NOT core complex
0.34	GO:0000932	P-body
0.33	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.38

GO:0042578

tr|T1FWP5|T1FWP5_HELRO
Uncharacterized protein
Search

tr|T1FWP6|T1FWP6_HELRO
Uncharacterized protein
Search

0.41	GO:0006402	mRNA catabolic process
0.40	GO:0009298	GDP-mannose biosynthetic process
0.40	GO:0035434	copper ion transmembrane transport
0.38	GO:0007186	G-protein coupled receptor signaling pathway
0.38	GO:0006396	RNA processing
0.36	GO:0006518	peptide metabolic process
0.36	GO:0006508	proteolysis
0.36	GO:0005975	carbohydrate metabolic process
0.36	GO:0043604	amide biosynthetic process
0.36	GO:0044267	cellular protein metabolic process

0.42	GO:0004654	polyribonucleotide nucleotidyltransferase activity
0.40	GO:0005375	copper ion transmembrane transporter activity
0.40	GO:0004476	mannose-6-phosphate isomerase activity
0.38	GO:0004930	G-protein coupled receptor activity
0.38	GO:0004222	metalloendopeptidase activity
0.37	GO:0003723	RNA binding
0.37	GO:0003735	structural constituent of ribosome
0.37	GO:0008270	zinc ion binding
0.34	GO:0019904	protein domain specific binding
0.33	GO:0019899	enzyme binding

0.52	GO:0005765	lysosomal membrane
0.38	GO:0005576	extracellular region
0.36	GO:0005840	ribosome
0.35	GO:0097636	intrinsic component of autophagosome membrane
0.35	GO:0031088	platelet dense granule membrane
0.35	GO:0044754	autolysosome
0.35	GO:0030670	phagocytic vesicle membrane
0.35	GO:0031166	integral component of vacuolar membrane
0.34	GO:0031902	late endosome membrane

0.42

EC:2.7.7.8

GO:0004654

tr|T1FWP7|T1FWP7_HELRO
Uncharacterized protein
Search

0.76	GO:0048193	Golgi vesicle transport
0.60	GO:1902504	regulation of signal transduction involved in mitotic G2 DNA damage checkpoint
0.57	GO:0060628	regulation of ER to Golgi vesicle-mediated transport
0.35	GO:0007049	cell cycle
0.34	GO:0015031	protein transport
0.34	GO:0001522	pseudouridine synthesis
0.32	GO:0006518	peptide metabolic process
0.32	GO:0043604	amide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:1901566	organonitrogen compound biosynthetic process

0.34	GO:0009982	pseudouridine synthase activity
0.33	GO:0005515	protein binding
0.33	GO:0003723	RNA binding
0.33	GO:0003735	structural constituent of ribosome

0.70	GO:0005783	endoplasmic reticulum
0.51	GO:0099023	tethering complex
0.44	GO:0043234	protein complex
0.43	GO:0044446	intracellular organelle part
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0005829	cytosol
0.33	GO:0005840	ribosome
0.30	GO:0044425	membrane part

0.34

EC:5.4.99.12

GO:0009982

tr|T1FWP8|T1FWP8_HELRO
Uncharacterized protein
Search

0.60	GO:0007165	signal transduction
0.36	GO:0043547	positive regulation of GTPase activity
0.33	GO:0051056	regulation of small GTPase mediated signal transduction
0.33	GO:0006037	cell wall chitin metabolic process
0.33	GO:0031505	fungal-type cell wall organization
0.33	GO:0006259	DNA metabolic process
0.32	GO:0006470	protein dephosphorylation
0.32	GO:0042254	ribosome biogenesis
0.32	GO:0006508	proteolysis

0.36	GO:0005096	GTPase activator activity
0.35	GO:0004531	deoxyribonuclease II activity
0.34	GO:0043022	ribosome binding
0.34	GO:0005509	calcium ion binding
0.32	GO:0004722	protein serine/threonine phosphatase activity
0.32	GO:0070001	aspartic-type peptidase activity
0.32	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.32	GO:0016757	transferase activity, transferring glycosyl groups
0.32	GO:0008270	zinc ion binding
0.32	GO:0004175	endopeptidase activity

0.34	GO:0043227	membrane-bounded organelle
0.34	GO:0043229	intracellular organelle
0.33	GO:0071944	cell periphery
0.33	GO:0000131	incipient cellular bud site
0.33	GO:0044444	cytoplasmic part
0.30	GO:0016020	membrane

0.35

EC:3.1.22.1

GO:0004531

tr|T1FWP9|T1FWP9_HELRO
Uncharacterized protein
Search

0.42

GO:0008298

intracellular mRNA localization

0.56	GO:0003723	RNA binding
0.41	GO:0016874	ligase activity

0.36

GO:0009507

chloroplast

0.41

GO:0016874

tr|T1FWQ0|T1FWQ0_HELRO
Uncharacterized protein
Search

tr|T1FWQ1|T1FWQ1_HELRO
Uncharacterized protein
Search

0.40	GO:1902476	chloride transmembrane transport
0.35	GO:0016579	protein deubiquitination
0.35	GO:0006511	ubiquitin-dependent protein catabolic process
0.34	GO:0055114	oxidation-reduction process

0.40	GO:0005247	voltage-gated chloride channel activity
0.36	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.35	GO:0020037	heme binding
0.35	GO:0005506	iron ion binding
0.35	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity

0.30

GO:0016020

membrane

0.36

GO:0016705

tr|T1FWQ2|T1FWQ2_HELRO
Uncharacterized protein
Search

0.56	GO:0016055	Wnt signaling pathway
0.53	GO:0007275	multicellular organism development
0.40	GO:0006030	chitin metabolic process
0.40	GO:0035725	sodium ion transmembrane transport
0.39	GO:0010447	response to acidic pH
0.39	GO:0043200	response to amino acid
0.39	GO:0007094	mitotic spindle assembly checkpoint
0.39	GO:0048477	oogenesis
0.38	GO:0006468	protein phosphorylation
0.38	GO:0016071	mRNA metabolic process

0.41	GO:0005272	sodium channel activity
0.40	GO:0008061	chitin binding
0.39	GO:0004672	protein kinase activity
0.38	GO:0003676	nucleic acid binding
0.38	GO:0042813	Wnt-activated receptor activity
0.36	GO:0017076	purine nucleotide binding
0.36	GO:0032553	ribonucleotide binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0004601	peroxidase activity
0.36	GO:0020037	heme binding

0.44	GO:0005576	extracellular region
0.41	GO:0005634	nucleus
0.36	GO:0005703	polytene chromosome puff
0.35	GO:0030014	CCR4-NOT complex
0.35	GO:0048786	presynaptic active zone
0.35	GO:0000428	DNA-directed RNA polymerase complex
0.35	GO:0005667	transcription factor complex
0.34	GO:0005874	microtubule
0.34	GO:0005783	endoplasmic reticulum
0.34	GO:0070013	intracellular organelle lumen

0.36	EC:1.11.1.7	GO:0004601
0.36	KEGG:R03532	GO:0004601

tr|T1FWQ3|T1FWQ3_HELRO
Uncharacterized protein
Search

tr|T1FWQ4|T1FWQ4_HELRO
Uncharacterized protein
Search

0.30

GO:0044425

membrane part

tr|T1FWQ5|T1FWQ5_HELRO
Uncharacterized protein
Search

tr|T1FWQ6|T1FWQ6_HELRO
Uncharacterized protein
Search

tr|T1FWQ7|T1FWQ7_HELRO
Uncharacterized protein
Search

0.51	Amyloid protein-binding protein 2

0.69	GO:0046907	intracellular transport
0.41	GO:0015031	protein transport
0.37	GO:0034613	cellular protein localization

0.39	GO:0005515	protein binding
0.38	GO:0003777	microtubule motor activity

0.76	GO:0030659	cytoplasmic vesicle membrane
0.44	GO:0005874	microtubule
0.40	GO:0005634	nucleus
0.39	GO:0005875	microtubule associated complex
0.30	GO:0016021	integral component of membrane

tr|T1FWQ8|T1FWQ8_HELRO
Uncharacterized protein
Search

tr|T1FWQ9|T1FWQ9_HELRO
Uncharacterized protein
Search

0.70	GO:0006541	glutamine metabolic process
0.38	GO:0006537	glutamate biosynthetic process
0.38	GO:0009065	glutamine family amino acid catabolic process
0.35	GO:1903955	positive regulation of protein targeting to mitochondrion
0.34	GO:0001967	suckling behavior
0.34	GO:0002087	regulation of respiratory gaseous exchange by neurological system process
0.34	GO:0042981	regulation of apoptotic process
0.34	GO:0071805	potassium ion transmembrane transport
0.34	GO:0072593	reactive oxygen species metabolic process
0.34	GO:0051289	protein homotetramerization

0.78	GO:0004359	glutaminase activity
0.37	GO:0004067	asparaginase activity
0.34	GO:0005249	voltage-gated potassium channel activity
0.33	GO:0005509	calcium ion binding

0.39	GO:0005739	mitochondrion
0.36	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.78

EC:3.5.1.2

GO:0004359

tr|T1FWR0|T1FWR0_HELRO
Uncharacterized protein
Search

0.42	GO:0036211	protein modification process
0.41	GO:0044267	cellular protein metabolic process
0.41	GO:0065007	biological regulation
0.41	GO:0016310	phosphorylation
0.40	GO:0035186	syncytial blastoderm mitotic cell cycle
0.39	GO:0006364	rRNA processing
0.38	GO:0006996	organelle organization
0.38	GO:0042273	ribosomal large subunit biogenesis
0.37	GO:0007154	cell communication
0.37	GO:0022618	ribonucleoprotein complex assembly

0.43	GO:0030554	adenyl nucleotide binding
0.43	GO:0004672	protein kinase activity
0.42	GO:0097367	carbohydrate derivative binding
0.42	GO:0008144	drug binding
0.42	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0005515	protein binding
0.42	GO:0016887	ATPase activity
0.40	GO:0140110	transcription regulator activity
0.39	GO:0003682	chromatin binding
0.37	GO:0003676	nucleic acid binding

0.40	GO:0030684	preribosome
0.40	GO:0005634	nucleus
0.39	GO:0070013	intracellular organelle lumen
0.38	GO:0044446	intracellular organelle part
0.37	GO:0000151	ubiquitin ligase complex
0.37	GO:0043234	protein complex
0.36	GO:0005694	chromosome
0.34	GO:0031248	protein acetyltransferase complex
0.34	GO:0005737	cytoplasm
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network

0.42	EC:3.6.1.3	GO:0016887
0.36	KEGG:R03876	GO:0004842

tr|T1FWR1|T1FWR1_HELRO
Uncharacterized protein
Search

tr|T1FWR2|T1FWR2_HELRO
Uncharacterized protein
Search

0.44	GO:0061101	neuroendocrine cell differentiation
0.43	GO:0051050	positive regulation of transport
0.43	GO:0090087	regulation of peptide transport
0.42	GO:0045944	positive regulation of transcription by RNA polymerase II
0.42	GO:0046883	regulation of hormone secretion
0.42	GO:0097435	supramolecular fiber organization
0.42	GO:0006996	organelle organization
0.41	GO:0051258	protein polymerization
0.40	GO:0023056	positive regulation of signaling
0.40	GO:0010647	positive regulation of cell communication

0.43	GO:0003676	nucleic acid binding
0.42	GO:0043015	gamma-tubulin binding
0.41	GO:0046872	metal ion binding
0.41	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.40	GO:0050825	ice binding
0.40	GO:0004386	helicase activity
0.39	GO:0004691	cAMP-dependent protein kinase activity
0.39	GO:0046983	protein dimerization activity
0.38	GO:0030554	adenyl nucleotide binding
0.38	GO:0097367	carbohydrate derivative binding

0.44	GO:0005634	nucleus
0.41	GO:0000922	spindle pole
0.40	GO:0005815	microtubule organizing center
0.40	GO:1990234	transferase complex
0.40	GO:0070013	intracellular organelle lumen
0.38	GO:0005952	cAMP-dependent protein kinase complex
0.38	GO:0005884	actin filament
0.38	GO:0000324	fungal-type vacuole
0.37	GO:0005615	extracellular space
0.36	GO:1905368	peptidase complex

0.41

EC:3.1.4.17

GO:0004114

tr|T1FWR3|T1FWR3_HELRO
Uncharacterized protein
Search

tr|T1FWR4|T1FWR4_HELRO
Uncharacterized protein
Search

0.11	Palmitoyltransferase (Fragment)

0.34	GO:0000056	ribosomal small subunit export from nucleus
0.34	GO:0007018	microtubule-based movement
0.34	GO:0006970	response to osmotic stress
0.34	GO:0032880	regulation of protein localization
0.34	GO:0034599	cellular response to oxidative stress
0.34	GO:0042274	ribosomal small subunit biogenesis
0.33	GO:0055114	oxidation-reduction process
0.33	GO:0006468	protein phosphorylation
0.32	GO:0034220	ion transmembrane transport

0.76	GO:0019706	protein-cysteine S-palmitoyltransferase activity
0.35	GO:0003723	RNA binding
0.35	GO:0005515	protein binding
0.34	GO:0003777	microtubule motor activity
0.33	GO:0016874	ligase activity
0.33	GO:0004674	protein serine/threonine kinase activity
0.33	GO:0016491	oxidoreductase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.36	GO:0005794	Golgi apparatus
0.34	GO:0016459	myosin complex
0.34	GO:0098588	bounding membrane of organelle
0.33	GO:0031984	organelle subcompartment
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.76

GO:0019706

tr|T1FWR5|T1FWR5_HELRO
Uncharacterized protein
Search

tr|T1FWR6|T1FWR6_HELRO
Uncharacterized protein
Search

0.39	GO:0016579	protein deubiquitination
0.38	GO:0006511	ubiquitin-dependent protein catabolic process
0.34	GO:0055114	oxidation-reduction process

0.40	GO:0005199	structural constituent of cell wall
0.39	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.39	GO:0004185	serine-type carboxypeptidase activity
0.37	GO:0050660	flavin adenine dinucleotide binding
0.37	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors

0.39	GO:0005669	transcription factor TFIID complex
0.30	GO:0016020	membrane

0.39

EC:3.4.19.12

GO:0036459

tr|T1FWR7|T1FWR7_HELRO
Uncharacterized protein
Search

0.43	GO:0016192	vesicle-mediated transport
0.42	GO:0006402	mRNA catabolic process
0.41	GO:0006886	intracellular protein transport
0.40	GO:0099120	socially cooperative development
0.40	GO:0043412	macromolecule modification
0.39	GO:0043085	positive regulation of catalytic activity
0.38	GO:0010918	positive regulation of mitochondrial membrane potential
0.38	GO:0098630	aggregation of unicellular organisms
0.38	GO:0044267	cellular protein metabolic process
0.38	GO:0010604	positive regulation of macromolecule metabolic process

0.39	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.39	GO:0043565	sequence-specific DNA binding
0.39	GO:0004842	ubiquitin-protein transferase activity
0.38	GO:0008270	zinc ion binding
0.38	GO:0008047	enzyme activator activity
0.37	GO:0005515	protein binding
0.37	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.37	GO:1901265	nucleoside phosphate binding
0.37	GO:0004037	allantoicase activity
0.36	GO:0008168	methyltransferase activity

0.46	GO:0030123	AP-3 adaptor complex
0.41	GO:0005634	nucleus
0.41	GO:0030014	CCR4-NOT complex
0.37	GO:0005667	transcription factor complex
0.36	GO:0020011	apicoplast
0.35	GO:0030135	coated vesicle
0.35	GO:0031248	protein acetyltransferase complex
0.35	GO:0000428	DNA-directed RNA polymerase complex
0.35	GO:1905368	peptidase complex
0.34	GO:0070013	intracellular organelle lumen

0.39	EC:2.7.10.2	GO:0004715
0.39	KEGG:R03876	GO:0004842

tr|T1FWR8|T1FWR8_HELRO
Uncharacterized protein
Search

tr|T1FWR9|T1FWR9_HELRO
Uncharacterized protein
Search

0.51	Leucine-zipper-like transcriptional regulator 1

0.39	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.38	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.38	GO:0030162	regulation of proteolysis

0.39

GO:0031625

ubiquitin protein ligase binding

0.41	GO:0000151	ubiquitin ligase complex
0.36	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

tr|T1FWS0|T1FWS0_HELRO
Uncharacterized protein
Search

0.88

Histone 1

0.73	GO:0006334	nucleosome assembly
0.35	GO:0032012	regulation of ARF protein signal transduction
0.35	GO:0030261	chromosome condensation
0.34	GO:0006508	proteolysis
0.34	GO:1901642	nucleoside transmembrane transport
0.34	GO:0065009	regulation of molecular function
0.33	GO:0006281	DNA repair
0.33	GO:0006396	RNA processing
0.33	GO:0009072	aromatic amino acid family metabolic process
0.33	GO:0090305	nucleic acid phosphodiester bond hydrolysis

0.52	GO:0003677	DNA binding
0.36	GO:0005515	protein binding
0.34	GO:0005509	calcium ion binding
0.34	GO:0003868	4-hydroxyphenylpyruvate dioxygenase activity
0.34	GO:0005337	nucleoside transmembrane transporter activity
0.34	GO:0098772	molecular function regulator
0.33	GO:0004519	endonuclease activity
0.33	GO:0003723	RNA binding
0.33	GO:0004930	G-protein coupled receptor activity
0.32	GO:0000166	nucleotide binding

0.69	GO:0000786	nucleosome
0.58	GO:0005634	nucleus
0.34	GO:0097458	neuron part
0.34	GO:0031974	membrane-enclosed lumen
0.34	GO:1904949	ATPase complex
0.30	GO:0016020	membrane

0.34

EC:1.13.11.27

GO:0003868

tr|T1FWS1|T1FWS1_HELRO
Uncharacterized protein
Search

tr|T1FWS2|T1FWS2_HELRO
Uncharacterized protein
Search

tr|T1FWS3|T1FWS3_HELRO
Uncharacterized protein
Search

0.11	Vangogh [Tribolium castaneum] (Fragment)

0.70	GO:0007275	multicellular organism development
0.47	GO:0060028	convergent extension involved in axis elongation
0.47	GO:0036342	post-anal tail morphogenesis
0.47	GO:0003402	planar cell polarity pathway involved in axis elongation
0.46	GO:0060601	lateral sprouting from an epithelium
0.46	GO:0060600	dichotomous subdivision of an epithelial terminal unit
0.46	GO:0048105	establishment of body hair planar orientation
0.46	GO:0042249	establishment of planar polarity of embryonic epithelium
0.46	GO:0090178	regulation of establishment of planar polarity involved in neural tube closure
0.46	GO:0043473	pigmentation

0.34

GO:0005515

protein binding

0.52	GO:0005886	plasma membrane
0.46	GO:0060187	cell pole
0.45	GO:0097517	contractile actin filament bundle
0.44	GO:0042641	actomyosin
0.43	GO:0045177	apical part of cell
0.43	GO:0030134	COPII-coated ER to Golgi transport vesicle
0.42	GO:0005911	cell-cell junction
0.30	GO:0016021	integral component of membrane

tr|T1FWS4|T1FWS4_HELRO
Uncharacterized protein
Search

tr|T1FWS5|T1FWS5_HELRO
Uncharacterized protein
Search

0.40	GO:0036211	protein modification process
0.39	GO:0016569	covalent chromatin modification
0.39	GO:0007018	microtubule-based movement
0.39	GO:0010468	regulation of gene expression
0.39	GO:2001141	regulation of RNA biosynthetic process
0.39	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.38	GO:0044267	cellular protein metabolic process
0.38	GO:0031154	culmination involved in sorocarp development
0.37	GO:0010587	miRNA catabolic process
0.37	GO:0043414	macromolecule methylation

0.43	GO:0003723	RNA binding
0.40	GO:0003700	DNA binding transcription factor activity
0.39	GO:0003777	microtubule motor activity
0.39	GO:0018024	histone-lysine N-methyltransferase activity
0.38	GO:0046872	metal ion binding
0.38	GO:0032555	purine ribonucleotide binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0004674	protein serine/threonine kinase activity
0.37	GO:0003924	GTPase activity
0.37	GO:0030554	adenyl nucleotide binding

0.46	GO:0005856	cytoskeleton
0.37	GO:0005634	nucleus
0.36	GO:0043234	protein complex
0.36	GO:0000428	DNA-directed RNA polymerase complex
0.36	GO:0020011	apicoplast
0.35	GO:0044446	intracellular organelle part
0.35	GO:0044233	ER-mitochondrion membrane contact site
0.35	GO:0031974	membrane-enclosed lumen
0.35	GO:0031301	integral component of organelle membrane
0.34	GO:0098805	whole membrane

0.39	EC:2.1.1.43	GO:0018024
0.35	KEGG:R03876	GO:0004842

tr|T1FWS6|T1FWS6_HELRO
Uncharacterized protein
Search

0.75	GO:0006428	isoleucyl-tRNA aminoacylation
0.70	GO:0106074	aminoacyl-tRNA metabolism involved in translational fidelity
0.45	GO:1903670	regulation of sprouting angiogenesis
0.37	GO:0001649	osteoblast differentiation

0.76	GO:0004822	isoleucine-tRNA ligase activity
0.70	GO:0002161	aminoacyl-tRNA editing activity
0.68	GO:0000049	tRNA binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0051020	GTPase binding
0.33	GO:0008270	zinc ion binding

0.52	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex
0.48	GO:0005737	cytoplasm
0.37	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.76	EC:6.1.1.5	GO:0004822
0.76	KEGG:R03656	GO:0004822

tr|T1FWS7|T1FWS7_HELRO
Uncharacterized protein
Search

tr|T1FWS8|T1FWS8_HELRO
Uncharacterized protein
Search

tr|T1FWS9|T1FWS9_HELRO
Uncharacterized protein
Search

0.50	GO:0006898	receptor-mediated endocytosis
0.45	GO:0006508	proteolysis
0.44	GO:0006030	chitin metabolic process
0.41	GO:0031505	fungal-type cell wall organization
0.40	GO:0019430	removal of superoxide radicals
0.38	GO:0044267	cellular protein metabolic process
0.37	GO:0055085	transmembrane transport
0.37	GO:0043632	modification-dependent macromolecule catabolic process
0.37	GO:0036211	protein modification process
0.37	GO:0030163	protein catabolic process

0.54	GO:0005044	scavenger receptor activity
0.49	GO:0004252	serine-type endopeptidase activity
0.44	GO:0017056	structural constituent of nuclear pore
0.44	GO:0008061	chitin binding
0.43	GO:0030246	carbohydrate binding
0.41	GO:0004784	superoxide dismutase activity
0.40	GO:0050825	ice binding
0.38	GO:0031177	phosphopantetheine binding
0.37	GO:0004842	ubiquitin-protein transferase activity
0.36	GO:0004672	protein kinase activity

0.44	GO:0005643	nuclear pore
0.44	GO:0005576	extracellular region
0.41	GO:0043190	ATP-binding cassette (ABC) transporter complex
0.40	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex

0.49	EC:3.4.21	GO:0004252
0.37	KEGG:R03876	GO:0004842

tr|T1FWT0|T1FWT0_HELRO
Uncharacterized protein
Search

tr|T1FWT1|T1FWT1_HELRO
Uncharacterized protein
Search

tr|T1FWT2|T1FWT2_HELRO
Uncharacterized protein
Search

tr|T1FWT3|T1FWT3_HELRO
Uncharacterized protein
Search

tr|T1FWT4|T1FWT4_HELRO
Uncharacterized protein
Search

tr|T1FWT5|T1FWT5_HELRO
Uncharacterized protein
Search

tr|T1FWT6|T1FWT6_HELRO
Uncharacterized protein
Search

0.55	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2

0.65	GO:0071805	potassium ion transmembrane transport
0.62	GO:0043269	regulation of ion transport
0.61	GO:0034762	regulation of transmembrane transport
0.53	GO:0016057	regulation of membrane potential in photoreceptor cell
0.53	GO:0007637	proboscis extension reflex
0.53	GO:0071632	optomotor response
0.53	GO:0050802	circadian sleep/wake cycle, sleep
0.52	GO:0071484	cellular response to light intensity
0.52	GO:0045938	positive regulation of circadian sleep/wake cycle, sleep
0.51	GO:0050433	regulation of catecholamine secretion

0.69	GO:0005216	ion channel activity
0.66	GO:0022832	voltage-gated channel activity
0.65	GO:0015079	potassium ion transmembrane transporter activity
0.44	GO:0030552	cAMP binding
0.33	GO:0015081	sodium ion transmembrane transporter activity

0.36

GO:0005887

integral component of plasma membrane

tr|T1FWT7|T1FWT7_HELRO
Uncharacterized protein
Search

tr|T1FWT8|T1FWT8_HELRO
Uncharacterized protein
Search

tr|T1FWT9|T1FWT9_HELRO
Uncharacterized protein
Search

tr|T1FWU0|T1FWU0_HELRO
Uncharacterized protein
Search

tr|T1FWU1|T1FWU1_HELRO
Uncharacterized protein
Search

0.61	GO:0007004	telomere maintenance via telomerase
0.61	GO:0000722	telomere maintenance via recombination
0.60	GO:0016233	telomere capping
0.59	GO:0070192	chromosome organization involved in meiotic cell cycle
0.58	GO:0007131	reciprocal meiotic recombination
0.56	GO:0000724	double-strand break repair via homologous recombination
0.52	GO:0032392	DNA geometric change
0.51	GO:0046939	nucleotide phosphorylation
0.48	GO:0090305	nucleic acid phosphodiester bond hydrolysis

0.62	GO:0051880	G-quadruplex DNA binding
0.62	GO:0003691	double-stranded telomeric DNA binding
0.60	GO:0043047	single-stranded telomeric DNA binding
0.60	GO:0000014	single-stranded DNA endodeoxyribonuclease activity
0.56	GO:0004017	adenylate kinase activity
0.55	GO:0003723	RNA binding
0.53	GO:0004003	ATP-dependent DNA helicase activity
0.53	GO:0008408	3'-5' exonuclease activity
0.44	GO:0030554	adenyl nucleotide binding
0.43	GO:0032555	purine ribonucleotide binding

0.59	GO:0030870	Mre11 complex
0.59	GO:0035861	site of double-strand break
0.58	GO:0000784	nuclear chromosome, telomeric region
0.57	GO:0000794	condensed nuclear chromosome
0.54	GO:0000790	nuclear chromatin

0.56

EC:2.7.4.3

GO:0004017

tr|T1FWU2|T1FWU2_HELRO
Uncharacterized protein
Search

0.92	Putative golgi-associated microtubule-binding protein hook3 (Fragment)

0.81	GO:0045022	early endosome to late endosome transport
0.80	GO:0008333	endosome to lysosome transport
0.78	GO:0007032	endosome organization
0.78	GO:0007040	lysosome organization
0.76	GO:0031122	cytoplasmic microtubule organization
0.74	GO:0022027	interkinetic nuclear migration
0.72	GO:0051645	Golgi localization
0.72	GO:0097150	neuronal stem cell population maintenance
0.71	GO:0034454	microtubule anchoring at centrosome
0.71	GO:0071539	protein localization to centrosome

0.72	GO:0008017	microtubule binding
0.68	GO:0042802	identical protein binding
0.66	GO:0051959	dynein light intermediate chain binding
0.52	GO:0003779	actin binding
0.44	GO:0008318	protein prenyltransferase activity
0.40	GO:0017137	Rab GTPase binding
0.37	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.36	GO:0016301	kinase activity
0.35	GO:0030554	adenyl nucleotide binding
0.35	GO:0097367	carbohydrate derivative binding

0.84	GO:0070695	FHF complex
0.80	GO:0030897	HOPS complex
0.72	GO:0005813	centrosome
0.66	GO:0005801	cis-Golgi network
0.66	GO:0044450	microtubule organizing center part
0.64	GO:0005829	cytosol
0.45	GO:0005874	microtubule
0.42	GO:0012505	endomembrane system
0.39	GO:0045202	synapse
0.39	GO:0030054	cell junction

0.44

EC:2.5.1

GO:0008318

tr|T1FWU3|T1FWU3_HELRO
Uncharacterized protein
Search

0.54	GO:0016311	dephosphorylation
0.46	GO:0045944	positive regulation of transcription by RNA polymerase II
0.40	GO:0006351	transcription, DNA-templated

0.57	GO:0004619	phosphoglycerate mutase activity
0.54	GO:0016791	phosphatase activity
0.48	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.48	GO:0000987	proximal promoter sequence-specific DNA binding
0.44	GO:0046983	protein dimerization activity

0.41	GO:0005634	nucleus
0.41	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.57

EC:5.4.2.1

GO:0004619

tr|T1FWU4|T1FWU4_HELRO
Uncharacterized protein
Search

tr|T1FWU5|T1FWU5_HELRO
Uncharacterized protein
Search

0.81	Retinoic acid receptor RXR-alpha-A

0.78	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.38	GO:0048384	retinoic acid receptor signaling pathway
0.36	GO:0051289	protein homotetramerization
0.35	GO:0051254	positive regulation of RNA metabolic process
0.35	GO:0010557	positive regulation of macromolecule biosynthetic process
0.35	GO:0031328	positive regulation of cellular biosynthetic process

0.80	GO:0003707	steroid hormone receptor activity
0.65	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.37	GO:0016918	retinal binding
0.37	GO:0044212	transcription regulatory region DNA binding
0.36	GO:0003690	double-stranded DNA binding
0.34	GO:0003779	actin binding
0.33	GO:0035100	ecdysone binding
0.33	GO:0003723	RNA binding

0.61	GO:0005634	nucleus
0.35	GO:0043005	neuron projection
0.34	GO:0120038	plasma membrane bounded cell projection part
0.34	GO:0005667	transcription factor complex
0.34	GO:0030427	site of polarized growth
0.33	GO:0036477	somatodendritic compartment
0.33	GO:0043235	receptor complex
0.32	GO:0005737	cytoplasm
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

tr|T1FWU6|T1FWU6_HELRO
Uncharacterized protein
Search

tr|T1FWU7|T1FWU7_HELRO
Uncharacterized protein
Search

0.85	GO:1904158	axonemal central apparatus assembly
0.83	GO:0060438	trachea development
0.82	GO:0021591	ventricular system development
0.78	GO:0003341	cilium movement
0.76	GO:0002064	epithelial cell development
0.47	GO:0010469	regulation of receptor activity
0.39	GO:0032259	methylation

0.48	GO:0005179	hormone activity
0.41	GO:0030976	thiamine pyrophosphate binding
0.39	GO:0008168	methyltransferase activity
0.39	GO:0000287	magnesium ion binding

0.86	GO:1990718	axonemal central pair projection
0.43	GO:0005576	extracellular region

0.39

GO:0008168

tr|T1FWU8|T1FWU8_HELRO
Uncharacterized protein
Search

TRMT10A

0.93	tRNA methyltransferase 10 A

0.60	GO:0032259	methylation
0.48	GO:0006400	tRNA modification
0.39	GO:0044260	cellular macromolecule metabolic process
0.38	GO:0010960	magnesium ion homeostasis

0.61	GO:0008168	methyltransferase activity
0.48	GO:0000049	tRNA binding
0.47	GO:0140101	catalytic activity, acting on a tRNA

0.50	GO:0005730	nucleolus
0.50	GO:0015629	actin cytoskeleton
0.48	GO:0005654	nucleoplasm
0.48	GO:0005829	cytosol
0.37	GO:0070062	extracellular exosome

0.61

GO:0008168

tr|T1FWU9|T1FWU9_HELRO
Uncharacterized protein
Search

0.85	CUGBP Elav family member 4

0.47	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.37	GO:0032224	positive regulation of synaptic transmission, cholinergic
0.37	GO:0032230	positive regulation of synaptic transmission, GABAergic
0.37	GO:0007271	synaptic transmission, cholinergic
0.36	GO:0045664	regulation of neuron differentiation
0.35	GO:0006397	mRNA processing
0.33	GO:0017148	negative regulation of translation
0.32	GO:2001141	regulation of RNA biosynthetic process

0.59	GO:0003723	RNA binding
0.35	GO:0042803	protein homodimerization activity
0.34	GO:0003713	transcription coactivator activity
0.32	GO:0003677	DNA binding

0.36	GO:0016607	nuclear speck
0.34	GO:0043234	protein complex
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|T1FWV0|T1FWV0_HELRO
Uncharacterized protein
Search

0.50	Nucleoside permease

0.79	GO:1901642	nucleoside transmembrane transport
0.40	GO:0072530	purine-containing compound transmembrane transport
0.39	GO:0015864	pyrimidine nucleoside transport
0.39	GO:0006863	purine nucleobase transport
0.37	GO:0072531	pyrimidine-containing compound transmembrane transport
0.37	GO:0015855	pyrimidine nucleobase transport

0.78	GO:0005337	nucleoside transmembrane transporter activity
0.45	GO:0015370	solute:sodium symporter activity
0.39	GO:0005345	purine nucleobase transmembrane transporter activity
0.37	GO:0005350	pyrimidine nucleobase transmembrane transporter activity
0.33	GO:0016887	ATPase activity
0.33	GO:0046983	protein dimerization activity
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.43

GO:0005887

integral component of plasma membrane

0.33

GO:0016887

tr|T1FWV1|T1FWV1_HELRO
Uncharacterized protein
Search

UBE2T

0.96	Ubiquitin conjugating enzyme E2 T

0.60	GO:0000209	protein polyubiquitination
0.56	GO:0051865	protein autoubiquitination
0.55	GO:0006513	protein monoubiquitination
0.51	GO:0006974	cellular response to DNA damage stimulus
0.46	GO:0006259	DNA metabolic process
0.45	GO:0010994	free ubiquitin chain polymerization
0.37	GO:0034644	cellular response to UV
0.36	GO:1902426	deactivation of mitotic spindle assembly checkpoint
0.35	GO:0006511	ubiquitin-dependent protein catabolic process
0.34	GO:0045116	protein neddylation

0.58	GO:0061631	ubiquitin conjugating enzyme activity
0.57	GO:0031625	ubiquitin protein ligase binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0003682	chromatin binding
0.49	GO:0061630	ubiquitin protein ligase activity
0.34	GO:0016874	ligase activity
0.34	GO:0019788	NEDD8 transferase activity

0.50	GO:0005730	nucleolus
0.44	GO:0031371	ubiquitin conjugating enzyme complex
0.38	GO:0005737	cytoplasm
0.34	GO:0005654	nucleoplasm

0.34

GO:0016874

tr|T1FWV2|T1FWV2_HELRO
Uncharacterized protein
Search

0.38	Glucosamine--fructose-6-phosphate aminotransferase 2

0.59	GO:1901137	carbohydrate derivative biosynthetic process
0.45	GO:1990830	cellular response to leukemia inhibitory factor
0.42	GO:0006047	UDP-N-acetylglucosamine metabolic process
0.41	GO:0006002	fructose 6-phosphate metabolic process
0.40	GO:0043413	macromolecule glycosylation
0.40	GO:0009100	glycoprotein metabolic process
0.37	GO:0036211	protein modification process
0.36	GO:0006541	glutamine metabolic process
0.36	GO:0044267	cellular protein metabolic process
0.36	GO:1901566	organonitrogen compound biosynthetic process

0.75	GO:0004360	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
0.54	GO:0097367	carbohydrate derivative binding
0.34	GO:0004044	amidophosphoribosyltransferase activity
0.33	GO:0005515	protein binding

0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.75	EC:2.6.1.16	GO:0004360
0.75	KEGG:R00768	GO:0004360

tr|T1FWV3|T1FWV3_HELRO
Uncharacterized protein
Search

0.78	metalloendoproteinase 4-MMP-like

0.61	GO:0006508	proteolysis
0.55	GO:0097186	amelogenesis
0.55	GO:0022617	extracellular matrix disassembly
0.47	GO:0030163	protein catabolic process
0.38	GO:1904807	negative regulation of protein oxidation
0.38	GO:1904109	positive regulation of cholesterol import
0.37	GO:1902479	positive regulation of defense response to bacterium, incompatible interaction
0.37	GO:1904000	positive regulation of eating behavior
0.37	GO:1900036	positive regulation of cellular response to heat
0.37	GO:0042395	ecdysis, collagen and cuticulin-based cuticle

0.70	GO:0004222	metalloendopeptidase activity
0.63	GO:0008270	zinc ion binding
0.35	GO:0004252	serine-type endopeptidase activity
0.33	GO:0005515	protein binding
0.32	GO:0005509	calcium ion binding

0.74	GO:0031012	extracellular matrix
0.34	GO:0031225	anchored component of membrane
0.34	GO:0005615	extracellular space
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.70

GO:0004222

tr|T1FWV4|T1FWV4_HELRO
Uncharacterized protein
Search

0.40	GO:0071938	vitamin A transport
0.40	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly
0.40	GO:1900244	positive regulation of synaptic vesicle endocytosis
0.39	GO:1900073	regulation of neuromuscular synaptic transmission
0.39	GO:2000331	regulation of terminal button organization
0.39	GO:0051124	synaptic growth at neuromuscular junction
0.39	GO:0007274	neuromuscular synaptic transmission
0.38	GO:0008306	associative learning
0.37	GO:0040012	regulation of locomotion
0.36	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity

0.49	GO:0005509	calcium ion binding
0.40	GO:0097109	neuroligin family protein binding
0.39	GO:0034185	apolipoprotein binding
0.39	GO:0042043	neurexin family protein binding

0.40	GO:0098889	intrinsic component of presynaptic membrane
0.40	GO:0098820	trans-synaptic protein complex
0.39	GO:0099699	integral component of synaptic membrane
0.38	GO:0031594	neuromuscular junction

tr|T1FWV5|T1FWV5_HELRO
Uncharacterized protein
Search

0.49

GO:0071805

potassium ion transmembrane transport

0.51

GO:0005267

potassium channel activity

0.54	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

tr|T1FWV6|T1FWV6_HELRO
Uncharacterized protein
Search

tr|T1FWV7|T1FWV7_HELRO
Uncharacterized protein
Search

0.10	Suppressor of cytokine signaling 4

0.69	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.69	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity
0.63	GO:0016567	protein ubiquitination
0.62	GO:0035556	intracellular signal transduction
0.47	GO:0007173	epidermal growth factor receptor signaling pathway
0.46	GO:0046426	negative regulation of JAK-STAT cascade
0.44	GO:0019221	cytokine-mediated signaling pathway
0.37	GO:0097699	vascular endothelial cell response to fluid shear stress
0.37	GO:0045629	negative regulation of T-helper 2 cell differentiation
0.37	GO:0045627	positive regulation of T-helper 1 cell differentiation

0.45	GO:0004860	protein kinase inhibitor activity
0.36	GO:0005154	epidermal growth factor receptor binding
0.36	GO:0030971	receptor tyrosine kinase binding
0.34	GO:0005126	cytokine receptor binding

0.45

GO:0005622

intracellular

tr|T1FWV8|T1FWV8_HELRO
Uncharacterized protein
Search

0.41	GO:1903506	regulation of nucleic acid-templated transcription
0.41	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.40	GO:0010468	regulation of gene expression
0.36	GO:0006351	transcription, DNA-templated
0.35	GO:0000413	protein peptidyl-prolyl isomerization
0.35	GO:0040034	regulation of development, heterochronic
0.35	GO:0006457	protein folding
0.34	GO:0044085	cellular component biogenesis
0.33	GO:0071824	protein-DNA complex subunit organization
0.33	GO:0016072	rRNA metabolic process

0.51	GO:0003676	nucleic acid binding
0.40	GO:0046872	metal ion binding
0.35	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.35	GO:0001152	transcription factor activity, RNA polymerase III type 1 promoter sequence-specific binding, TFIIIC recruiting
0.34	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.33	GO:0005216	ion channel activity
0.33	GO:0005515	protein binding

0.39	GO:0005634	nucleus
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.35

GO:0003755

tr|T1FWV9|T1FWV9_HELRO
Uncharacterized protein
Search

tr|T1FWW0|T1FWW0_HELRO
Uncharacterized protein
Search

0.33	Splicing factor arginine/serine-rich 6

0.52	GO:0048025	negative regulation of mRNA splicing, via spliceosome
0.37	GO:0032868	response to insulin
0.36	GO:0002244	hematopoietic progenitor cell differentiation
0.35	GO:0008380	RNA splicing
0.34	GO:0006397	mRNA processing
0.34	GO:0006369	termination of RNA polymerase II transcription
0.34	GO:0006886	intracellular protein transport
0.34	GO:0071166	ribonucleoprotein complex localization
0.34	GO:0051169	nuclear transport
0.34	GO:0031123	RNA 3'-end processing

0.59	GO:0003723	RNA binding
0.33	GO:0003839	gamma-glutamylcyclotransferase activity
0.33	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.33	GO:0008270	zinc ion binding
0.33	GO:0005515	protein binding
0.33	GO:0003700	DNA binding transcription factor activity
0.32	GO:0004672	protein kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.49	GO:0016607	nuclear speck
0.34	GO:0005742	mitochondrial outer membrane translocase complex
0.30	GO:0016021	integral component of membrane

0.33

EC:2.3.2.4

GO:0003839

tr|T1FWW1|T1FWW1_HELRO
Uncharacterized protein
Search

0.68	Synapsin III

0.82	GO:0099643	signal release from synapse
0.82	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.76	GO:0006836	neurotransmitter transport
0.72	GO:0001505	regulation of neurotransmitter levels
0.69	GO:0051649	establishment of localization in cell
0.46	GO:0097479	synaptic vesicle localization
0.36	GO:0050804	modulation of chemical synaptic transmission
0.36	GO:0051588	regulation of neurotransmitter transport
0.35	GO:1903530	regulation of secretion by cell
0.35	GO:0060341	regulation of cellular localization

0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0019901	protein kinase binding
0.38	GO:0046872	metal ion binding
0.38	GO:0048306	calcium-dependent protein binding
0.37	GO:0008092	cytoskeletal protein binding
0.34	GO:0046983	protein dimerization activity
0.32	GO:0005215	transporter activity

0.82	GO:0008021	synaptic vesicle
0.52	GO:0099501	exocytic vesicle membrane
0.51	GO:0014069	postsynaptic density
0.48	GO:0043209	myelin sheath
0.47	GO:0000795	synaptonemal complex
0.46	GO:0048786	presynaptic active zone
0.46	GO:0030424	axon
0.42	GO:0005856	cytoskeleton
0.40	GO:0031201	SNARE complex
0.39	GO:0030054	cell junction

tr|T1FWW2|T1FWW2_HELRO
Uncharacterized protein
Search

PFDN1

0.88	Prefoldin subunit 1

0.69	GO:0006457	protein folding
0.45	GO:0007010	cytoskeleton organization
0.37	GO:0021549	cerebellum development
0.37	GO:0042113	B cell activation
0.37	GO:0021537	telencephalon development
0.36	GO:0030029	actin filament-based process
0.35	GO:0015948	methanogenesis
0.33	GO:0032259	methylation
0.33	GO:2001141	regulation of RNA biosynthetic process
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.71	GO:0051082	unfolded protein binding
0.52	GO:0044183	protein binding involved in protein folding
0.36	GO:0042086	5-methyl-5,6,7,8-tetrahydromethanopterin-dependent methyltransferase activity
0.34	GO:0008172	S-methyltransferase activity
0.33	GO:0003700	DNA binding transcription factor activity

0.80	GO:0016272	prefoldin complex
0.37	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.34

GO:0008172

tr|T1FWW3|T1FWW3_HELRO
Uncharacterized protein
Search

tr|T1FWW4|T1FWW4_HELRO
Uncharacterized protein
Search

0.56	Follicle-stimulating hormone receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.52	GO:0019933	cAMP-mediated signaling
0.51	GO:0008584	male gonad development
0.44	GO:0060658	nipple morphogenesis
0.43	GO:0060427	lung connective tissue development
0.43	GO:0007567	parturition
0.40	GO:0030198	extracellular matrix organization
0.39	GO:0030154	cell differentiation
0.37	GO:0032870	cellular response to hormone stimulus
0.37	GO:0060359	response to ammonium ion

0.72	GO:0004930	G-protein coupled receptor activity
0.59	GO:0016500	protein-hormone receptor activity
0.42	GO:0042562	hormone binding
0.39	GO:0030594	neurotransmitter receptor activity
0.35	GO:0001653	peptide receptor activity
0.34	GO:0042277	peptide binding
0.33	GO:0046872	metal ion binding
0.33	GO:0009881	photoreceptor activity
0.33	GO:0099589	serotonin receptor activity
0.33	GO:0008373	sialyltransferase activity

0.40	GO:0005886	plasma membrane
0.36	GO:0005622	intracellular
0.33	GO:0001750	photoreceptor outer segment
0.30	GO:0016021	integral component of membrane

0.33

EC:2.4.99

GO:0008373

tr|T1FWW5|T1FWW5_HELRO
Uncharacterized protein
Search

TBC1D20

0.94	Putative gtpase activator protein (Fragment)

0.57	GO:1902953	positive regulation of ER to Golgi vesicle-mediated transport
0.57	GO:0046726	positive regulation by virus of viral protein levels in host cell
0.56	GO:0044829	positive regulation by host of viral genome replication
0.56	GO:0070309	lens fiber cell morphogenesis
0.56	GO:0090110	cargo loading into COPII-coated vesicle
0.55	GO:0001675	acrosome assembly
0.55	GO:0072520	seminiferous tubule development
0.54	GO:0034389	lipid particle organization
0.52	GO:0007030	Golgi organization
0.51	GO:0043547	positive regulation of GTPase activity

0.54	GO:0017137	Rab GTPase binding
0.52	GO:0005096	GTPase activator activity
0.35	GO:0004672	protein kinase activity
0.34	GO:0004427	inorganic diphosphatase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0000287	magnesium ion binding

0.52	GO:0030173	integral component of Golgi membrane
0.51	GO:0031965	nuclear membrane
0.50	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane

0.34	EC:3.6.1.1	GO:0004427
0.34	KEGG:R00004	GO:0004427

tr|T1FWW6|T1FWW6_HELRO
Uncharacterized protein
Search

tr|T1FWW7|T1FWW7_HELRO
AP-3 complex subunit beta
Search

AP3B2

0.81	AP-3 complex subunit beta

0.69	GO:0006886	intracellular protein transport
0.68	GO:0016192	vesicle-mediated transport
0.53	GO:0008089	anterograde axonal transport
0.52	GO:0047496	vesicle transport along microtubule
0.51	GO:0097480	establishment of synaptic vesicle localization
0.32	GO:0006518	peptide metabolic process
0.32	GO:0043604	amide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:1901566	organonitrogen compound biosynthetic process
0.32	GO:0010467	gene expression

0.41	GO:0030276	clathrin binding
0.32	GO:0005215	transporter activity
0.32	GO:0003735	structural constituent of ribosome

0.80	GO:0030123	AP-3 adaptor complex
0.52	GO:1904115	axon cytoplasm
0.36	GO:0030665	clathrin-coated vesicle membrane
0.35	GO:0030131	clathrin adaptor complex
0.35	GO:0005794	Golgi apparatus
0.34	GO:0030137	COPI-coated vesicle
0.33	GO:0031984	organelle subcompartment
0.32	GO:0005840	ribosome

tr|T1FWW8|T1FWW8_HELRO
Uncharacterized protein
Search

SRSF5

0.91	Serine and arginine rich splicing factor 5

0.52	GO:0048025	negative regulation of mRNA splicing, via spliceosome
0.41	GO:0032868	response to insulin
0.39	GO:0097421	liver regeneration
0.38	GO:0008380	RNA splicing
0.38	GO:0033120	positive regulation of RNA splicing
0.38	GO:0006397	mRNA processing
0.38	GO:0071375	cellular response to peptide hormone stimulus
0.37	GO:0002244	hematopoietic progenitor cell differentiation
0.37	GO:0006369	termination of RNA polymerase II transcription
0.36	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus

0.58	GO:0003723	RNA binding
0.39	GO:0043422	protein kinase B binding
0.37	GO:0050733	RS domain binding

0.51	GO:0031981	nuclear lumen
0.47	GO:0005829	cytosol
0.43	GO:0043232	intracellular non-membrane-bounded organelle

tr|T1FWW9|T1FWW9_HELRO
Uncharacterized protein
Search

0.52	GO:1905167	positive regulation of lysosomal protein catabolic process
0.51	GO:0002265	astrocyte activation involved in immune response
0.51	GO:1900223	positive regulation of amyloid-beta clearance
0.51	GO:0097242	amyloid-beta clearance
0.50	GO:0045056	transcytosis
0.50	GO:1904646	cellular response to amyloid-beta
0.50	GO:0006898	receptor-mediated endocytosis
0.49	GO:1903078	positive regulation of protein localization to plasma membrane
0.48	GO:0032092	positive regulation of protein binding
0.48	GO:0045807	positive regulation of endocytosis

0.66	GO:0005509	calcium ion binding
0.52	GO:0016964	alpha-2 macroglobulin receptor activity
0.50	GO:0032050	clathrin heavy chain binding
0.50	GO:0034185	apolipoprotein binding
0.45	GO:0032403	protein complex binding
0.37	GO:0004252	serine-type endopeptidase activity
0.36	GO:0030226	apolipoprotein receptor activity
0.36	GO:0005041	low-density lipoprotein receptor activity
0.35	GO:0043395	heparan sulfate proteoglycan binding
0.35	GO:0070325	lipoprotein particle receptor binding

0.49	GO:0043235	receptor complex
0.48	GO:0098590	plasma membrane region
0.47	GO:0005768	endosome
0.41	GO:0045177	apical part of cell
0.40	GO:0005905	clathrin-coated pit
0.40	GO:0030425	dendrite
0.40	GO:0005794	Golgi apparatus
0.40	GO:0005903	brush border
0.40	GO:0030139	endocytic vesicle
0.40	GO:0009897	external side of plasma membrane

0.37

GO:0004252

tr|T1FWX0|T1FWX0_HELRO
Uncharacterized protein
Search

0.61	GO:0006508	proteolysis
0.43	GO:0008217	regulation of blood pressure
0.41	GO:0060177	regulation of angiotensin metabolic process
0.41	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I
0.41	GO:0043171	peptide catabolic process
0.41	GO:0050886	endocrine process
0.39	GO:0042445	hormone metabolic process
0.38	GO:0051604	protein maturation
0.34	GO:0007267	cell-cell signaling
0.33	GO:1990947	exit from meiosis

0.67	GO:0008237	metallopeptidase activity
0.66	GO:0004177	aminopeptidase activity
0.63	GO:0008270	zinc ion binding
0.41	GO:0042277	peptide binding
0.33	GO:0042802	identical protein binding
0.32	GO:0003924	GTPase activity
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0019001	guanyl nucleotide binding
0.32	GO:0016301	kinase activity
0.32	GO:0016491	oxidoreductase activity

0.38	GO:0005783	endoplasmic reticulum
0.36	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0031984	organelle subcompartment
0.33	GO:0097431	mitotic spindle pole
0.32	GO:0005886	plasma membrane
0.32	GO:0000793	condensed chromosome
0.32	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.66

EC:3.4.11

GO:0004177

tr|T1FWX1|T1FWX1_HELRO
Uncharacterized protein
Search

tr|T1FWX2|T1FWX2_HELRO
Uncharacterized protein
Search

0.42	GO:0048172	regulation of short-term neuronal synaptic plasticity
0.42	GO:0008586	imaginal disc-derived wing vein morphogenesis
0.42	GO:0007474	imaginal disc-derived wing vein specification
0.42	GO:0046716	muscle cell cellular homeostasis
0.42	GO:0007274	neuromuscular synaptic transmission
0.42	GO:0046928	regulation of neurotransmitter secretion
0.41	GO:0030010	establishment of cell polarity
0.36	GO:0007517	muscle organ development

0.63	GO:0008270	zinc ion binding
0.57	GO:0003779	actin binding
0.42	GO:0050699	WW domain binding
0.38	GO:0008307	structural constituent of muscle

0.41	GO:0016010	dystrophin-associated glycoprotein complex
0.40	GO:0045202	synapse
0.39	GO:0005856	cytoskeleton
0.38	GO:0042383	sarcolemma
0.36	GO:0005938	cell cortex
0.35	GO:0098590	plasma membrane region
0.34	GO:0030054	cell junction

tr|T1FWX3|T1FWX3_HELRO
Methylthioribose-1-phosphate isomerase
Search

0.57	Methylthioribose-1-phosphate isomerase

0.75	GO:0019509	L-methionine salvage from methylthioadenosine
0.73	GO:0019284	L-methionine salvage from S-adenosylmethionine
0.42	GO:0006413	translational initiation
0.36	GO:0006898	receptor-mediated endocytosis
0.35	GO:0071732	cellular response to nitric oxide
0.34	GO:0071281	cellular response to iron ion
0.34	GO:0071369	cellular response to ethylene stimulus
0.34	GO:0016310	phosphorylation
0.33	GO:0055114	oxidation-reduction process
0.33	GO:0006508	proteolysis

0.79	GO:0046523	S-methyl-5-thioribose-1-phosphate isomerase activity
0.42	GO:0003743	translation initiation factor activity
0.37	GO:0005044	scavenger receptor activity
0.36	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor
0.36	GO:0046522	S-methyl-5-thioribose kinase activity
0.36	GO:0005507	copper ion binding
0.34	GO:0008239	dipeptidyl-peptidase activity
0.34	GO:0008017	microtubule binding
0.33	GO:0004672	protein kinase activity
0.33	GO:0008270	zinc ion binding

0.60	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.34	GO:0055044	symplast
0.34	GO:0005911	cell-cell junction
0.33	GO:0005874	microtubule
0.30	GO:0031224	intrinsic component of membrane

0.79	EC:5.3.1.23	GO:0046523
0.79	KEGG:R04420	GO:0046523

tr|T1FWX4|T1FWX4_HELRO
Uncharacterized protein
Search

0.49	Transmembrane protein 26

0.34	GO:0008641	ubiquitin-like modifier activating enzyme activity
0.33	GO:0016779	nucleotidyltransferase activity
0.33	GO:0008270	zinc ion binding
0.33	GO:0003723	RNA binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0031224

intrinsic component of membrane

0.33

GO:0016779

tr|T1FWX5|T1FWX5_HELRO
Uncharacterized protein
Search

EHD1

0.68	EH domain-containing protein 1

0.79	GO:0032456	endocytic recycling
0.49	GO:0051260	protein homooligomerization
0.47	GO:1990255	subsynaptic reticulum organization
0.46	GO:0048052	R1/R6 cell differentiation
0.46	GO:0007291	sperm individualization
0.46	GO:0007474	imaginal disc-derived wing vein specification
0.46	GO:0008587	imaginal disc-derived wing margin morphogenesis
0.45	GO:0042670	retinal cone cell differentiation
0.45	GO:0045466	R7 cell differentiation
0.44	GO:0048477	oogenesis

0.67	GO:0005509	calcium ion binding
0.66	GO:0005525	GTP binding
0.50	GO:0045296	cadherin binding
0.34	GO:0019904	protein domain specific binding
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0016887	ATPase activity
0.32	GO:0003676	nucleic acid binding

0.53	GO:0055038	recycling endosome membrane
0.49	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0071212	subsynaptic reticulum
0.46	GO:0005783	endoplasmic reticulum
0.36	GO:0031901	early endosome membrane
0.35	GO:0070062	extracellular exosome
0.35	GO:0020018	ciliary pocket membrane
0.34	GO:0043209	myelin sheath
0.34	GO:0030139	endocytic vesicle
0.33	GO:0005829	cytosol

0.33

GO:0016887

tr|T1FWX6|T1FWX6_HELRO
Uncharacterized protein
Search

0.37	G-protein-linked Acetylcholine Receptor

0.72	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway
0.57	GO:0046541	saliva secretion
0.56	GO:0045987	positive regulation of smooth muscle contraction
0.42	GO:0007271	synaptic transmission, cholinergic
0.41	GO:0006939	smooth muscle contraction
0.40	GO:0003056	regulation of vascular smooth muscle contraction
0.38	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.38	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.36	GO:0007218	neuropeptide signaling pathway
0.35	GO:0050890	cognition

0.72	GO:0016907	G-protein coupled acetylcholine receptor activity
0.38	GO:0016492	G-protein coupled neurotensin receptor activity
0.36	GO:0042166	acetylcholine binding
0.34	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.33	GO:0005515	protein binding
0.32	GO:0098772	molecular function regulator

0.56	GO:0005887	integral component of plasma membrane
0.52	GO:0045211	postsynaptic membrane
0.50	GO:0030054	cell junction
0.36	GO:0016323	basolateral plasma membrane
0.35	GO:0043005	neuron projection
0.35	GO:0032279	asymmetric synapse
0.35	GO:0036477	somatodendritic compartment
0.35	GO:0098793	presynapse
0.34	GO:0120038	plasma membrane bounded cell projection part

0.34

GO:0004715

tr|T1FWX7|T1FWX7_HELRO
Uncharacterized protein
Search

GABARAPL2

0.97	Gamma-aminobutyric acid receptor-associated protein 2

0.77	GO:0006914	autophagy
0.55	GO:1901799	negative regulation of proteasomal protein catabolic process
0.50	GO:0006995	cellular response to nitrogen starvation
0.49	GO:0061726	mitochondrion disassembly
0.47	GO:0007033	vacuole organization
0.44	GO:0070925	organelle assembly
0.37	GO:0006891	intra-Golgi vesicle-mediated transport
0.36	GO:0032781	positive regulation of ATPase activity
0.36	GO:0015031	protein transport
0.34	GO:0043241	protein complex disassembly

0.51	GO:0031625	ubiquitin protein ligase binding
0.37	GO:0051117	ATPase binding
0.36	GO:0000149	SNARE binding
0.35	GO:0050811	GABA receptor binding
0.35	GO:0048487	beta-tubulin binding
0.34	GO:0008017	microtubule binding
0.33	GO:0004252	serine-type endopeptidase activity

0.58	GO:0000421	autophagosome membrane
0.50	GO:0000139	Golgi membrane
0.43	GO:0005829	cytosol
0.37	GO:0031410	cytoplasmic vesicle

0.33

GO:0004252

tr|T1FWX8|T1FWX8_HELRO
Anoctamin
Search

0.65

Anoctamin

0.65	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus
0.63	GO:1902476	chloride transmembrane transport
0.61	GO:0034605	cellular response to heat
0.49	GO:0050965	detection of temperature stimulus involved in sensory perception of pain
0.45	GO:0061588	calcium activated phospholipid scrambling
0.45	GO:0050829	defense response to Gram-negative bacterium
0.45	GO:0015705	iodide transport
0.43	GO:0002407	dendritic cell chemotaxis
0.42	GO:0030501	positive regulation of bone mineralization
0.41	GO:0034767	positive regulation of ion transmembrane transport

0.68	GO:0046983	protein dimerization activity
0.52	GO:0061778	intracellular chloride channel activity
0.48	GO:0097603	temperature-gated ion channel activity
0.46	GO:0015111	iodide transmembrane transporter activity
0.45	GO:0005247	voltage-gated chloride channel activity
0.43	GO:0005227	calcium activated cation channel activity
0.36	GO:0017128	phospholipid scramblase activity
0.36	GO:0042802	identical protein binding

0.46	GO:0005886	plasma membrane
0.42	GO:0045177	apical part of cell
0.36	GO:0009986	cell surface
0.36	GO:0098552	side of membrane
0.35	GO:0070062	extracellular exosome
0.34	GO:0034707	chloride channel complex
0.32	GO:0005737	cytoplasm

tr|T1FWX9|T1FWX9_HELRO
Uncharacterized protein
Search

0.10	Putative acetylcholine receptor (Fragment)

0.69	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.34	GO:0006511	ubiquitin-dependent protein catabolic process
0.32	GO:0006812	cation transport

0.75	GO:0005230	extracellular ligand-gated ion channel activity
0.71	GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential
0.70	GO:0004888	transmembrane signaling receptor activity
0.66	GO:0022835	transmitter-gated channel activity
0.65	GO:0140135	mechanosensitive cation channel activity
0.34	GO:0070003	threonine-type peptidase activity
0.33	GO:0008270	zinc ion binding
0.33	GO:0004175	endopeptidase activity
0.33	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
0.32	GO:0005509	calcium ion binding

0.68	GO:0045211	postsynaptic membrane
0.64	GO:0030054	cell junction
0.34	GO:0019773	proteasome core complex, alpha-subunit complex
0.33	GO:0005634	nucleus
0.32	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.33	EC:3.2.1.113	GO:0004571
0.33	KEGG:R05982 KEGG:R06722	GO:0004571

tr|T1FWY0|T1FWY0_HELRO
Anion exchange protein
Search

0.65	Anion exchange protein (Fragment)

0.69	GO:0098656	anion transmembrane transport
0.69	GO:0015698	inorganic anion transport
0.41	GO:0015701	bicarbonate transport
0.38	GO:0006814	sodium ion transport
0.38	GO:0030641	regulation of cellular pH
0.38	GO:0007271	synaptic transmission, cholinergic
0.38	GO:0032228	regulation of synaptic transmission, GABAergic
0.37	GO:0046685	response to arsenic-containing substance
0.37	GO:0098660	inorganic ion transmembrane transport
0.36	GO:0098655	cation transmembrane transport

0.83	GO:0005452	inorganic anion exchanger activity
0.41	GO:0015301	anion:anion antiporter activity
0.41	GO:0008510	sodium:bicarbonate symporter activity
0.37	GO:0015108	chloride transmembrane transporter activity

0.37	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1FWY1|T1FWY1_HELRO
Uncharacterized protein
Search

0.42	Adenylate kinase isoenzyme 1

0.60	GO:0046939	nucleotide phosphorylation
0.54	GO:0006172	ADP biosynthetic process
0.51	GO:0046034	ATP metabolic process
0.50	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process
0.50	GO:0046033	AMP metabolic process
0.48	GO:0006221	pyrimidine nucleotide biosynthetic process
0.47	GO:0009142	nucleoside triphosphate biosynthetic process
0.39	GO:0007050	cell cycle arrest
0.36	GO:0032496	response to lipopolysaccharide
0.34	GO:0097503	sialylation

0.72	GO:0019205	nucleobase-containing compound kinase activity
0.62	GO:0016776	phosphotransferase activity, phosphate group as acceptor
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0008373	sialyltransferase activity
0.34	GO:0030695	GTPase regulator activity
0.32	GO:0008270	zinc ion binding

0.44	GO:0005737	cytoplasm
0.40	GO:0005634	nucleus
0.39	GO:0036126	sperm flagellum
0.35	GO:0044441	ciliary part
0.35	GO:0099513	polymeric cytoskeletal fiber
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.62

EC:2.7.4

GO:0016776

tr|T1FWY2|T1FWY2_HELRO
Alpha-mannosidase
Search

0.38	Alpha-mannosidase

0.81	GO:0006013	mannose metabolic process
0.41	GO:0006517	protein deglycosylation
0.35	GO:0007611	learning or memory

0.79	GO:0004559	alpha-mannosidase activity
0.70	GO:0030246	carbohydrate binding
0.53	GO:0046872	metal ion binding
0.33	GO:0042302	structural constituent of cuticle
0.32	GO:0003676	nucleic acid binding
0.32	GO:0036094	small molecule binding

0.37	GO:0005773	vacuole
0.37	GO:0009505	plant-type cell wall
0.36	GO:0048046	apoplast
0.35	GO:0098805	whole membrane
0.35	GO:0098588	bounding membrane of organelle
0.34	GO:0044446	intracellular organelle part
0.34	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.79

EC:3.2.1.24

GO:0004559

tr|T1FWY3|T1FWY3_HELRO
Uncharacterized protein
Search

MTMR4

0.82	myotubularin-related protein 4

0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.71	GO:0007179	transforming growth factor beta receptor signaling pathway
0.54	GO:0060304	regulation of phosphatidylinositol dephosphorylation
0.45	GO:0046856	phosphatidylinositol dephosphorylation
0.38	GO:0014877	response to muscle inactivity involved in regulation of muscle adaptation
0.36	GO:1904562	phosphatidylinositol 5-phosphate metabolic process
0.35	GO:2000785	regulation of autophagosome assembly
0.35	GO:0042149	cellular response to glucose starvation
0.35	GO:0046855	inositol phosphate dephosphorylation
0.34	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway

0.74	GO:0004725	protein tyrosine phosphatase activity
0.66	GO:0004722	protein serine/threonine phosphatase activity
0.51	GO:0019903	protein phosphatase binding
0.49	GO:0046872	metal ion binding
0.46	GO:0052866	phosphatidylinositol phosphate phosphatase activity
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0032561	guanyl ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0004672	protein kinase activity
0.33	GO:0003735	structural constituent of ribosome

0.48	GO:0005768	endosome
0.35	GO:0005829	cytosol
0.35	GO:0005615	extracellular space
0.34	GO:0019898	extrinsic component of membrane
0.33	GO:0044433	cytoplasmic vesicle part
0.33	GO:0098805	whole membrane
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0005840	ribosome

0.74

GO:0004725

tr|T1FWY4|T1FWY4_HELRO
Uncharacterized protein
Search

0.31	Long-chain-fatty-acid--CoA ligase

0.57	GO:0090316	positive regulation of intracellular protein transport
0.56	GO:0071482	cellular response to light stimulus
0.41	GO:0016310	phosphorylation

0.47	GO:0016874	ligase activity
0.42	GO:0016301	kinase activity
0.38	GO:0016787	hydrolase activity

0.50	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.47

GO:0016874

tr|T1FWY5|T1FWY5_HELRO
Uncharacterized protein
Search

ASCC3

0.78	Activating signal cointegrator 1 complex subunit

0.55	GO:0006307	DNA dealkylation involved in DNA repair
0.55	GO:0008283	cell proliferation
0.50	GO:0032392	DNA geometric change
0.37	GO:0006351	transcription, DNA-templated
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:0010468	regulation of gene expression

0.55	GO:0032559	adenyl ribonucleotide binding
0.55	GO:0043140	ATP-dependent 3'-5' DNA helicase activity
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0003676	nucleic acid binding
0.34	GO:0005515	protein binding

0.61	GO:0099053	activating signal cointegrator 1 complex
0.49	GO:0005829	cytosol
0.46	GO:0005634	nucleus
0.35	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

tr|T1FWY6|T1FWY6_HELRO
Uncharacterized protein
Search

WWP2

0.57	E3 ubiquitin-protein ligase

0.73	GO:0016567	protein ubiquitination
0.71	GO:0006511	ubiquitin-dependent protein catabolic process
0.55	GO:0006858	extracellular transport
0.55	GO:1901016	regulation of potassium ion transmembrane transporter activity
0.55	GO:0032410	negative regulation of transporter activity
0.54	GO:0043433	negative regulation of DNA binding transcription factor activity
0.53	GO:0051224	negative regulation of protein transport
0.53	GO:0010498	proteasomal protein catabolic process
0.52	GO:0000122	negative regulation of transcription by RNA polymerase II
0.51	GO:0042391	regulation of membrane potential

0.74	GO:0061630	ubiquitin protein ligase activity
0.55	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.54	GO:0001085	RNA polymerase II transcription factor binding
0.53	GO:0016874	ligase activity

0.46	GO:0005576	extracellular region
0.44	GO:0005634	nucleus
0.39	GO:0005737	cytoplasm
0.37	GO:0031982	vesicle
0.34	GO:0000151	ubiquitin ligase complex
0.30	GO:0016020	membrane

0.53

GO:0016874

tr|T1FWY7|T1FWY7_HELRO
Uncharacterized protein
Search

0.52	GO:0006468	protein phosphorylation
0.44	GO:0007165	signal transduction
0.42	GO:0006952	defense response
0.37	GO:0046007	negative regulation of activated T cell proliferation
0.37	GO:0006955	immune response
0.37	GO:0050707	regulation of cytokine secretion
0.37	GO:0008056	ocellus development
0.37	GO:0050709	negative regulation of protein secretion
0.37	GO:0001818	negative regulation of cytokine production
0.36	GO:0048518	positive regulation of biological process

0.52	GO:0004672	protein kinase activity
0.48	GO:0032559	adenyl ribonucleotide binding
0.46	GO:0043168	anion binding
0.46	GO:0008144	drug binding
0.36	GO:0060089	molecular transducer activity
0.35	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.35	GO:0017046	peptide hormone binding
0.35	GO:0004871	signal transducer activity
0.34	GO:0003727	single-stranded RNA binding
0.33	GO:0022857	transmembrane transporter activity

0.35	GO:0005654	nucleoplasm
0.34	GO:0031226	intrinsic component of plasma membrane
0.30	GO:0016021	integral component of membrane

0.35

GO:0032440

tr|T1FWY8|T1FWY8_HELRO
Uncharacterized protein
Search

0.12	Putative rala-binding protein 1 (Fragment)

0.61	GO:0007165	signal transduction
0.42	GO:0043547	positive regulation of GTPase activity
0.42	GO:1900753	doxorubicin transport
0.40	GO:0006855	drug transmembrane transport
0.39	GO:0006897	endocytosis
0.38	GO:1903378	positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
0.38	GO:0048662	negative regulation of smooth muscle cell proliferation
0.37	GO:0007052	mitotic spindle organization
0.36	GO:0051056	regulation of small GTPase mediated signal transduction
0.36	GO:0006935	chemotaxis

0.45	GO:0017160	Ral GTPase binding
0.43	GO:0048365	Rac GTPase binding
0.42	GO:0005096	GTPase activator activity
0.39	GO:0015238	drug transmembrane transporter activity
0.38	GO:0016887	ATPase activity
0.37	GO:0015399	primary active transmembrane transporter activity

0.37	GO:0005829	cytosol
0.37	GO:0000922	spindle pole
0.36	GO:0043005	neuron projection
0.34	GO:0005886	plasma membrane

0.38

GO:0016887

tr|T1FWY9|T1FWY9_HELRO
Uncharacterized protein
Search

0.76	GO:0006303	double-strand break repair via nonhomologous end joining
0.63	GO:0006468	protein phosphorylation
0.46	GO:1902400	intracellular signal transduction involved in G1 DNA damage checkpoint
0.45	GO:1902402	signal transduction involved in mitotic DNA damage checkpoint
0.45	GO:0031571	mitotic G1 DNA damage checkpoint
0.45	GO:0002328	pro-B cell differentiation
0.45	GO:0002326	B cell lineage commitment
0.44	GO:0033152	immunoglobulin V(D)J recombination
0.44	GO:0035234	ectopic germ cell programmed cell death
0.44	GO:0002568	somatic diversification of T cell receptor genes

0.86	GO:0004677	DNA-dependent protein kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0003677	DNA binding
0.41	GO:0019904	protein domain specific binding
0.40	GO:0008134	transcription factor binding
0.40	GO:0019899	enzyme binding
0.32	GO:0004812	aminoacyl-tRNA ligase activity

0.59	GO:0005634	nucleus
0.46	GO:0070419	nonhomologous end joining complex
0.40	GO:0005667	transcription factor complex
0.40	GO:0070013	intracellular organelle lumen
0.40	GO:0032993	protein-DNA complex
0.38	GO:0043232	intracellular non-membrane-bounded organelle
0.37	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.86

GO:0004677

tr|T1FWZ1|T1FWZ1_HELRO
Uncharacterized protein
Search

tr|T1FWZ2|T1FWZ2_HELRO
Uncharacterized protein
Search

0.10	Flagellar hook-length control protein FliK

0.45	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.44	GO:0071230	cellular response to amino acid stimulus
0.43	GO:0007155	cell adhesion
0.43	GO:0030198	extracellular matrix organization
0.40	GO:0007275	multicellular organism development
0.40	GO:0007528	neuromuscular junction development
0.38	GO:0009888	tissue development
0.38	GO:0033622	integrin activation
0.37	GO:0051894	positive regulation of focal adhesion assembly
0.37	GO:0018996	molting cycle, collagen and cuticulin-based cuticle

0.74	GO:0005201	extracellular matrix structural constituent
0.38	GO:0005509	calcium ion binding
0.38	GO:0048407	platelet-derived growth factor binding
0.38	GO:0004252	serine-type endopeptidase activity
0.37	GO:0005178	integrin binding
0.36	GO:0042302	structural constituent of cuticle

0.68	GO:0005581	collagen trimer
0.66	GO:0005604	basement membrane
0.46	GO:0098645	collagen network
0.37	GO:0031594	neuromuscular junction
0.36	GO:0005615	extracellular space
0.35	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.38

GO:0004252

tr|T1FWZ3|T1FWZ3_HELRO
Uncharacterized protein
Search

0.65	Centromere/kinetochore protein zw10-like protein-like protein (Fragment)

0.75	GO:0000278	mitotic cell cycle
0.53	GO:0034501	protein localization to kinetochore
0.53	GO:0007088	regulation of mitotic nuclear division
0.53	GO:0051294	establishment of spindle orientation
0.53	GO:0045930	negative regulation of mitotic cell cycle
0.53	GO:0051310	metaphase plate congression
0.53	GO:0000075	cell cycle checkpoint
0.53	GO:1901990	regulation of mitotic cell cycle phase transition
0.52	GO:0006888	ER to Golgi vesicle-mediated transport
0.52	GO:0007030	Golgi organization

0.35	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.35	GO:0019237	centromeric DNA binding
0.34	GO:0005242	inward rectifier potassium channel activity
0.34	GO:0005515	protein binding
0.33	GO:0060090	molecular adaptor activity
0.33	GO:0004803	transposase activity
0.32	GO:0044877	macromolecular complex binding

0.77	GO:0000775	chromosome, centromeric region
0.61	GO:0005634	nucleus
0.56	GO:0070939	Dsl1/NZR complex
0.54	GO:0005828	kinetochore microtubule
0.50	GO:0000922	spindle pole
0.46	GO:0005829	cytosol
0.37	GO:0000793	condensed chromosome
0.37	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0036063	acroblast
0.34	GO:0051233	spindle midzone

0.35

EC:3.4.19.12

GO:0036459

tr|T1FWZ4|T1FWZ4_HELRO
Uncharacterized protein
Search

0.86	G-protein-linked acetylcholine receptor protein 2

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.64	GO:0095500	acetylcholine receptor signaling pathway
0.39	GO:0007271	synaptic transmission, cholinergic
0.36	GO:0090520	sphingolipid mediated signaling pathway
0.34	GO:0018108	peptidyl-tyrosine phosphorylation
0.33	GO:0019933	cAMP-mediated signaling

0.72	GO:0004930	G-protein coupled receptor activity
0.64	GO:0015464	acetylcholine receptor activity
0.34	GO:0004715	non-membrane spanning protein tyrosine kinase activity

0.51	GO:0005887	integral component of plasma membrane
0.32	GO:0005739	mitochondrion

0.34

GO:0004715

tr|T1FWZ5|T1FWZ5_HELRO
Uncharacterized protein
Search

0.50	Dual specificity phosphatase

0.79	GO:0000188	inactivation of MAPK activity
0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.51	GO:0001706	endoderm formation
0.49	GO:0035970	peptidyl-threonine dephosphorylation
0.48	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.40	GO:0060795	cell fate commitment involved in formation of primary germ layer
0.40	GO:0001708	cell fate specification
0.35	GO:0042981	regulation of apoptotic process
0.34	GO:0033574	response to testosterone
0.34	GO:0071850	mitotic cell cycle arrest

0.79	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity
0.74	GO:0004725	protein tyrosine phosphatase activity
0.51	GO:0008330	protein tyrosine/threonine phosphatase activity
0.50	GO:1990439	MAP kinase serine/threonine phosphatase activity
0.46	GO:0051019	mitogen-activated protein kinase binding
0.34	GO:0004222	metalloendopeptidase activity
0.33	GO:0019838	growth factor binding
0.33	GO:0016301	kinase activity
0.32	GO:0046872	metal ion binding

0.45	GO:0044428	nuclear part
0.41	GO:0031974	membrane-enclosed lumen
0.40	GO:0012505	endomembrane system
0.39	GO:0031967	organelle envelope
0.39	GO:0031090	organelle membrane
0.33	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.79

GO:0017017

tr|T1FWZ6|T1FWZ6_HELRO
Uncharacterized protein
Search

HSF

0.48	Heat shock transcription factor

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.47	GO:0043010	camera-type eye development
0.46	GO:0070207	protein homotrimerization
0.46	GO:0009408	response to heat
0.44	GO:0072738	cellular response to diamide
0.43	GO:1903936	cellular response to sodium arsenite
0.43	GO:0008284	positive regulation of cell proliferation
0.43	GO:0043497	regulation of protein heterodimerization activity

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.43	GO:0061770	translation elongation factor binding
0.43	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding
0.42	GO:0051879	Hsp90 protein binding
0.42	GO:1990841	promoter-specific chromatin binding
0.42	GO:0043621	protein self-association
0.41	GO:0031490	chromatin DNA binding
0.40	GO:0019901	protein kinase binding
0.40	GO:0001012	RNA polymerase II regulatory region DNA binding

0.61	GO:0005634	nucleus
0.42	GO:0097431	mitotic spindle pole
0.41	GO:0070013	intracellular organelle lumen
0.40	GO:0048471	perinuclear region of cytoplasm
0.40	GO:0035770	ribonucleoprotein granule
0.40	GO:0000776	kinetochore
0.40	GO:0005813	centrosome
0.38	GO:0005829	cytosol
0.36	GO:0000791	euchromatin
0.36	GO:0000792	heterochromatin

tr|T1FWZ7|T1FWZ7_HELRO
Uncharacterized protein
Search

HSD17B10

0.38	Short chain alcohol dehydrogenase/3 hydroxyacyl coa dehydrogenase

0.51	GO:0055114	oxidation-reduction process
0.47	GO:0007018	microtubule-based movement
0.37	GO:0005975	carbohydrate metabolic process
0.34	GO:0032253	dense core granule localization
0.34	GO:0051296	establishment of meiotic spindle orientation
0.34	GO:1904811	positive regulation of dense core granule transport
0.34	GO:0009409	response to cold
0.34	GO:1902473	regulation of protein localization to synapse
0.34	GO:0051932	synaptic transmission, GABAergic
0.34	GO:0051661	maintenance of centrosome location

0.52	GO:0016491	oxidoreductase activity
0.47	GO:0003777	microtubule motor activity
0.42	GO:0016887	ATPase activity
0.40	GO:0032559	adenyl ribonucleotide binding
0.39	GO:0008144	drug binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.34	GO:0042393	histone binding
0.33	GO:0004312	fatty acid synthase activity
0.32	GO:0000049	tRNA binding

0.48	GO:0030286	dynein complex
0.34	GO:0030678	mitochondrial ribonuclease P complex
0.34	GO:1904115	axon cytoplasm
0.33	GO:0000922	spindle pole
0.33	GO:0000776	kinetochore
0.33	GO:0005634	nucleus
0.33	GO:0005938	cell cortex
0.33	GO:0045202	synapse
0.33	GO:0012505	endomembrane system
0.32	GO:0031967	organelle envelope

0.52

GO:0016491

tr|T1FWZ8|T1FWZ8_HELRO
Uncharacterized protein
Search

WASF1

0.60	Wiskott-Aldrich syndrome protein family member 3

0.74	GO:0030036	actin cytoskeleton organization
0.56	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus
0.56	GO:0072673	lamellipodium morphogenesis
0.55	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway
0.55	GO:0016601	Rac protein signal transduction
0.55	GO:0097484	dendrite extension
0.53	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation
0.47	GO:0006897	endocytosis
0.36	GO:0035855	megakaryocyte development
0.36	GO:0051497	negative regulation of stress fiber assembly

0.67	GO:0003779	actin binding
0.53	GO:0048365	Rac GTPase binding
0.53	GO:0051018	protein kinase A binding
0.49	GO:0032403	protein complex binding
0.35	GO:0045296	cadherin binding
0.35	GO:0017124	SH3 domain binding

0.69	GO:0005856	cytoskeleton
0.54	GO:0031209	SCAR complex
0.52	GO:0030027	lamellipodium
0.49	GO:0005741	mitochondrial outer membrane
0.39	GO:0030054	cell junction
0.37	GO:0045202	synapse
0.36	GO:0001726	ruffle
0.35	GO:0005769	early endosome
0.35	GO:0045120	pronucleus
0.34	GO:0032154	cleavage furrow

tr|T1FWZ9|T1FWZ9_HELRO
Uncharacterized protein
Search

0.62	GO:0015701	bicarbonate transport
0.62	GO:0019532	oxalate transport
0.60	GO:0051453	regulation of intracellular pH
0.57	GO:0010469	regulation of receptor activity
0.57	GO:0042391	regulation of membrane potential
0.56	GO:1902476	chloride transmembrane transport
0.56	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic
0.55	GO:1902358	sulfate transmembrane transport

0.63	GO:0005184	neuropeptide hormone activity
0.63	GO:0015106	bicarbonate transmembrane transporter activity
0.62	GO:0019531	oxalate transmembrane transporter activity
0.60	GO:0015301	anion:anion antiporter activity
0.59	GO:0000175	3'-5'-exoribonuclease activity
0.57	GO:0008271	secondary active sulfate transmembrane transporter activity
0.57	GO:0005254	chloride channel activity
0.42	GO:0003676	nucleic acid binding

0.51

GO:0005887

integral component of plasma membrane

0.59

EC:3.1.13

GO:0000175

tr|T1FX00|T1FX00_HELRO
Uncharacterized protein
Search

0.38	SET domain-containing 1Bb

0.78	GO:0034968	histone lysine methylation
0.51	GO:2001141	regulation of RNA biosynthetic process
0.51	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.50	GO:0010468	regulation of gene expression
0.43	GO:1903341	regulation of meiotic DNA double-strand break formation
0.43	GO:0035066	positive regulation of histone acetylation
0.43	GO:0018027	peptidyl-lysine dimethylation
0.42	GO:0018023	peptidyl-lysine trimethylation
0.42	GO:0030437	ascospore formation
0.41	GO:0000723	telomere maintenance

0.79	GO:0018024	histone-lysine N-methyltransferase activity
0.39	GO:0003676	nucleic acid binding
0.36	GO:0046872	metal ion binding
0.36	GO:0004518	nuclease activity
0.34	GO:0051219	phosphoprotein binding
0.34	GO:0004130	cytochrome-c peroxidase activity
0.33	GO:0004672	protein kinase activity
0.33	GO:0003735	structural constituent of ribosome
0.33	GO:0004824	lysine-tRNA ligase activity
0.33	GO:0030554	adenyl nucleotide binding

0.61	GO:0005634	nucleus
0.60	GO:0005694	chromosome
0.46	GO:0034708	methyltransferase complex
0.42	GO:0070013	intracellular organelle lumen
0.39	GO:0044446	intracellular organelle part
0.33	GO:0044444	cytoplasmic part
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016020	membrane

0.79

GO:0018024

tr|T1FX01|T1FX01_HELRO
Uncharacterized protein
Search

tr|T1FX02|T1FX02_HELRO
Uncharacterized protein
Search

0.20	Glutathione S-transferase protein

0.30

GO:0008152

metabolic process

0.54

GO:0004364

glutathione transferase activity

0.54

EC:2.5.1.18

GO:0004364

tr|T1FX03|T1FX03_HELRO
Uncharacterized protein
Search

DMAP1

0.92	DNA methyltransferase 1-associated protein 1

0.85	GO:0043968	histone H2A acetylation
0.84	GO:0043967	histone H4 acetylation
0.78	GO:0006338	chromatin remodeling
0.71	GO:0045892	negative regulation of transcription, DNA-templated
0.65	GO:0006281	DNA repair
0.56	GO:0032259	methylation
0.52	GO:0042993	positive regulation of transcription factor import into nucleus
0.46	GO:0006357	regulation of transcription by RNA polymerase II
0.44	GO:0060041	retina development in camera-type eye
0.37	GO:0045471	response to ethanol

0.56	GO:0008168	methyltransferase activity
0.53	GO:0003714	transcription corepressor activity
0.52	GO:0001103	RNA polymerase II repressing transcription factor binding
0.34	GO:0003677	DNA binding

0.80	GO:0035267	NuA4 histone acetyltransferase complex
0.47	GO:0005657	replication fork
0.45	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.56

GO:0008168

tr|T1FX04|T1FX04_HELRO
Uncharacterized protein
Search

0.10	Flagellar hook-length control protein FliK

0.46	GO:0030198	extracellular matrix organization
0.45	GO:0072001	renal system development
0.44	GO:0048513	animal organ development
0.41	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.40	GO:0007528	neuromuscular junction development
0.40	GO:0001101	response to acid chemical
0.39	GO:0001569	branching involved in blood vessel morphogenesis
0.39	GO:1901700	response to oxygen-containing compound
0.38	GO:0071417	cellular response to organonitrogen compound
0.38	GO:0007155	cell adhesion

0.69	GO:0005201	extracellular matrix structural constituent
0.40	GO:0048407	platelet-derived growth factor binding
0.35	GO:0004252	serine-type endopeptidase activity
0.35	GO:0097493	structural molecule activity conferring elasticity
0.35	GO:0042302	structural constituent of cuticle
0.34	GO:0005509	calcium ion binding
0.33	GO:0004867	serine-type endopeptidase inhibitor activity
0.32	GO:0004222	metalloendopeptidase activity
0.32	GO:0003677	DNA binding
0.32	GO:0003700	DNA binding transcription factor activity

0.70	GO:0005581	collagen trimer
0.64	GO:0005604	basement membrane
0.49	GO:0098645	collagen network
0.37	GO:0005615	extracellular space
0.35	GO:0030056	hemidesmosome
0.35	GO:0031594	neuromuscular junction
0.35	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0016020	membrane

0.35

GO:0004252

tr|T1FX05|T1FX05_HELRO
Uncharacterized protein
Search

0.60	GO:0035556	intracellular signal transduction
0.51	GO:0035335	peptidyl-tyrosine dephosphorylation
0.35	GO:0007018	microtubule-based movement
0.35	GO:0006886	intracellular protein transport
0.33	GO:0016310	phosphorylation

0.51	GO:0004725	protein tyrosine phosphatase activity
0.49	GO:0046872	metal ion binding
0.37	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.36	GO:0008536	Ran GTPase binding
0.35	GO:0003777	microtubule motor activity
0.35	GO:0008017	microtubule binding
0.34	GO:0003676	nucleic acid binding
0.34	GO:0016301	kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding

0.44	GO:0005622	intracellular
0.30	GO:0016020	membrane

0.51

GO:0004725

tr|T1FX06|T1FX06_HELRO
Uncharacterized protein
Search

UCP2

0.85	Mitochondrial uncoupling protein B

0.75	GO:0006839	mitochondrial transport
0.52	GO:0051881	regulation of mitochondrial membrane potential
0.52	GO:0001666	response to hypoxia
0.48	GO:1990845	adaptive thermogenesis
0.46	GO:0009409	response to cold
0.41	GO:0032868	response to insulin
0.41	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus
0.41	GO:0071391	cellular response to estrogen stimulus
0.41	GO:0000303	response to superoxide
0.41	GO:0015992	proton transport

0.50	GO:0017077	oxidative phosphorylation uncoupler activity
0.33	GO:0005515	protein binding
0.33	GO:0015078	hydrogen ion transmembrane transporter activity

0.61	GO:0031966	mitochondrial membrane
0.40	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1FX07|T1FX07_HELRO
Uncharacterized protein
Search

0.41	GO:0006366	transcription by RNA polymerase II
0.41	GO:0022008	neurogenesis
0.39	GO:0045944	positive regulation of transcription by RNA polymerase II
0.37	GO:0007165	signal transduction
0.37	GO:0097534	lymphoid lineage cell migration
0.37	GO:0031077	post-embryonic camera-type eye development
0.37	GO:0035701	hematopoietic stem cell migration
0.36	GO:0002681	somatic recombination of T cell receptor gene segments
0.36	GO:0003334	keratinocyte development
0.36	GO:0021756	striatum development

0.51	GO:0003676	nucleic acid binding
0.40	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.37	GO:0046872	metal ion binding
0.33	GO:0016817	hydrolase activity, acting on acid anhydrides
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0097367	carbohydrate derivative binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.38	GO:0005634	nucleus
0.35	GO:0043005	neuron projection
0.30	GO:0016020	membrane

0.33

EC:3.6

GO:0016817

tr|T1FX08|T1FX08_HELRO
Uncharacterized protein
Search

0.78	GO:0035023	regulation of Rho protein signal transduction
0.66	GO:0065009	regulation of molecular function
0.58	GO:0006468	protein phosphorylation
0.46	GO:0035556	intracellular signal transduction
0.46	GO:0045599	negative regulation of fat cell differentiation
0.34	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway
0.34	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:0043065	positive regulation of apoptotic process

0.78	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.62	GO:0004674	protein serine/threonine kinase activity
0.47	GO:0032559	adenyl ribonucleotide binding
0.46	GO:0008144	drug binding
0.46	GO:0035639	purine ribonucleoside triphosphate binding

0.38	GO:0005622	intracellular
0.33	GO:0099512	supramolecular fiber
0.32	GO:0043228	non-membrane-bounded organelle
0.32	GO:0044422	organelle part
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.62

GO:0004674

tr|T1FX09|T1FX09_HELRO
Uncharacterized protein
Search

0.61	Zinc finger MYM-type protein (Fragment)

0.38	GO:0006357	regulation of transcription by RNA polymerase II
0.35	GO:0007275	multicellular organism development
0.33	GO:0016310	phosphorylation

0.68	GO:0046983	protein dimerization activity
0.39	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.36	GO:0003677	DNA binding
0.33	GO:0016301	kinase activity

0.38	GO:0005654	nucleoplasm
0.34	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

tr|T1FX10|T1FX10_HELRO
Uncharacterized protein
Search

0.60	GO:0005975	carbohydrate metabolic process
0.30	GO:0044237	cellular metabolic process

0.66	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.39	GO:0030246	carbohydrate binding

0.30

GO:0044425

membrane part

0.66

GO:0004553

tr|T1FX11|T1FX11_HELRO
Uncharacterized protein
Search

tr|T1FX12|T1FX12_HELRO
Uncharacterized protein
Search

0.37	Cytochrome b ascorbate-dependent protein 3

0.53	GO:0055114	oxidation-reduction process
0.37	GO:0006091	generation of precursor metabolites and energy

0.45	GO:0000293	ferric-chelate reductase activity
0.41	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.55	GO:0031902	late endosome membrane
0.54	GO:0005765	lysosomal membrane
0.33	GO:0009507	chloroplast
0.30	GO:0031224	intrinsic component of membrane

0.45

EC:1.16.1.7

GO:0000293

tr|T1FX13|T1FX13_HELRO
Uncharacterized protein
Search

0.48	GO:0035848	oviduct morphogenesis
0.47	GO:0048621	post-embryonic digestive tract morphogenesis
0.46	GO:0060729	intestinal epithelial structure maintenance
0.45	GO:0055013	cardiac muscle cell development
0.39	GO:0007155	cell adhesion
0.38	GO:0005975	carbohydrate metabolic process
0.37	GO:0006351	transcription, DNA-templated
0.37	GO:0006508	proteolysis
0.37	GO:1903506	regulation of nucleic acid-templated transcription
0.37	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.50	GO:0005201	extracellular matrix structural constituent
0.46	GO:0005509	calcium ion binding
0.41	GO:0030246	carbohydrate binding
0.40	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.39	GO:0004252	serine-type endopeptidase activity
0.38	GO:0043565	sequence-specific DNA binding
0.38	GO:0003700	DNA binding transcription factor activity

0.59	GO:0005581	collagen trimer
0.50	GO:0005604	basement membrane
0.38	GO:0019867	outer membrane
0.30	GO:0016021	integral component of membrane

0.40

GO:0004553

tr|T1FX14|T1FX14_HELRO
Uncharacterized protein
Search

0.78	GO:0034968	histone lysine methylation
0.59	GO:0035441	cell migration involved in vasculogenesis
0.57	GO:0060977	coronary vasculature morphogenesis
0.56	GO:1905634	regulation of protein localization to chromatin
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010793	regulation of mRNA export from nucleus
0.56	GO:0034340	response to type I interferon
0.56	GO:0032727	positive regulation of interferon-alpha production
0.56	GO:0060039	pericardium development

0.79	GO:0018024	histone-lysine N-methyltransferase activity
0.55	GO:0043014	alpha-tubulin binding
0.34	GO:0003777	microtubule motor activity
0.34	GO:0008017	microtubule binding
0.33	GO:0046872	metal ion binding
0.33	GO:0003723	RNA binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.67	GO:0005694	chromosome
0.58	GO:0005634	nucleus
0.34	GO:0044446	intracellular organelle part
0.34	GO:0120114	Sm-like protein family complex
0.34	GO:0099512	supramolecular fiber
0.34	GO:0015630	microtubule cytoskeleton
0.33	GO:0043233	organelle lumen
0.33	GO:1990904	ribonucleoprotein complex
0.30	GO:0031224	intrinsic component of membrane

0.79

GO:0018024

tr|T1FX15|T1FX15_HELRO
Phosphoinositide phospholipase C
Search

0.24	Phosphoinositide phospholipase C

0.70	GO:0016042	lipid catabolic process
0.70	GO:0032228	regulation of synaptic transmission, GABAergic
0.61	GO:0035556	intracellular signal transduction
0.54	GO:0002337	B-1a B cell differentiation
0.53	GO:0050859	negative regulation of B cell receptor signaling pathway
0.53	GO:0002322	B cell proliferation involved in immune response
0.53	GO:1900122	positive regulation of receptor binding
0.51	GO:0007214	gamma-aminobutyric acid signaling pathway
0.50	GO:0033135	regulation of peptidyl-serine phosphorylation
0.43	GO:0032065	cortical protein anchoring

0.80	GO:0004435	phosphatidylinositol phospholipase C activity
0.71	GO:0050811	GABA receptor binding
0.69	GO:0070679	inositol 1,4,5 trisphosphate binding
0.60	GO:0004871	signal transducer activity
0.48	GO:0005509	calcium ion binding
0.41	GO:0005543	phospholipid binding
0.33	GO:0016757	transferase activity, transferring glycosyl groups
0.32	GO:0016779	nucleotidyltransferase activity

0.44	GO:0005622	intracellular
0.36	GO:0071944	cell periphery
0.34	GO:0043227	membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.80	EC:3.1.4.11	GO:0004435
0.80	KEGG:R03435	GO:0004435

tr|T1FX16|T1FX16_HELRO
Uncharacterized protein
Search

KCNH1

0.78	Potassium voltage-gated channel protein eag

0.74	GO:0034765	regulation of ion transmembrane transport
0.73	GO:0071805	potassium ion transmembrane transport
0.63	GO:0023014	signal transduction by protein phosphorylation
0.61	GO:0000160	phosphorelay signal transduction system
0.48	GO:0021576	hindbrain formation
0.46	GO:0001756	somitogenesis
0.44	GO:0071277	cellular response to calcium ion
0.42	GO:0048015	phosphatidylinositol-mediated signaling
0.42	GO:0042391	regulation of membrane potential
0.41	GO:0042127	regulation of cell proliferation

0.78	GO:0005249	voltage-gated potassium channel activity
0.64	GO:0000155	phosphorelay sensor kinase activity
0.43	GO:1902936	phosphatidylinositol bisphosphate binding
0.35	GO:0071889	14-3-3 protein binding
0.35	GO:0044325	ion channel binding
0.34	GO:0005516	calmodulin binding
0.34	GO:0019901	protein kinase binding
0.34	GO:0030551	cyclic nucleotide binding
0.34	GO:0046982	protein heterodimerization activity
0.34	GO:0042802	identical protein binding

0.59	GO:0005887	integral component of plasma membrane
0.44	GO:0005622	intracellular
0.42	GO:0034705	potassium channel complex
0.40	GO:0031982	vesicle
0.40	GO:0098805	whole membrane
0.40	GO:0098588	bounding membrane of organelle
0.39	GO:0012505	endomembrane system
0.35	GO:0030673	axolemma
0.35	GO:0042734	presynaptic membrane
0.35	GO:0043204	perikaryon

0.64

EC:2.7.3

GO:0000155

tr|T1FX17|T1FX17_HELRO
Ditrans,polycis-polyprenyl diphosphate synthase ((2E,6E)-farnesyl diphosphate specific)
Search

DHDDS

0.73	Dehydrodolichyl diphosphate synthase complex subunit DHDDS

0.74	GO:0006486	protein glycosylation
0.49	GO:0016094	polyprenol biosynthetic process
0.47	GO:0050908	detection of light stimulus involved in visual perception
0.46	GO:0042462	eye photoreceptor cell development
0.35	GO:0006489	dolichyl diphosphate biosynthetic process

0.68	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups
0.35	GO:0031492	nucleosomal DNA binding
0.33	GO:0005515	protein binding

0.35	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0000785	chromatin
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.68

EC:2.5 EC:2.5.1

GO:0016765

tr|T1FX18|T1FX18_HELRO
Uncharacterized protein
Search

0.49	Mitogen-activated protein kinase kinase kinase

0.63	GO:0006468	protein phosphorylation
0.52	GO:0043410	positive regulation of MAPK cascade
0.50	GO:0070304	positive regulation of stress-activated protein kinase signaling cascade
0.50	GO:0046328	regulation of JNK cascade
0.48	GO:0043405	regulation of MAP kinase activity
0.48	GO:0032147	activation of protein kinase activity
0.48	GO:0071902	positive regulation of protein serine/threonine kinase activity
0.47	GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress
0.46	GO:1902170	cellular response to reactive nitrogen species
0.46	GO:0048082	regulation of adult chitin-containing cuticle pigmentation

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0005057	signal transducer activity, downstream of receptor
0.45	GO:0019903	protein phosphatase binding
0.43	GO:0019901	protein kinase binding
0.43	GO:0019904	protein domain specific binding
0.42	GO:0042803	protein homodimerization activity
0.40	GO:0000287	magnesium ion binding

0.47	GO:1990604	IRE1-TRAF2-ASK1 complex
0.44	GO:1902911	protein kinase complex
0.36	GO:0009897	external side of plasma membrane
0.34	GO:0005829	cytosol
0.33	GO:0015630	microtubule cytoskeleton
0.30	GO:0016021	integral component of membrane

0.33

EC:1.2.1

GO:0016620

tr|T1FX19|T1FX19_HELRO
Uncharacterized protein
Search

ISL1

0.96	LIM homeodomain transcription factor islet-1

0.60	GO:0048936	peripheral nervous system neuron axonogenesis
0.59	GO:0060913	cardiac cell fate determination
0.59	GO:0048665	neuron fate specification
0.58	GO:0003139	secondary heart field specification
0.58	GO:0071657	positive regulation of granulocyte colony-stimulating factor production
0.58	GO:0031016	pancreas development
0.58	GO:0021524	visceral motor neuron differentiation
0.58	GO:0032730	positive regulation of interleukin-1 alpha production
0.57	GO:0003266	regulation of secondary heart field cardioblast proliferation
0.57	GO:0060379	cardiac muscle cell myoblast differentiation

0.64	GO:0043565	sequence-specific DNA binding
0.57	GO:0043425	bHLH transcription factor binding
0.56	GO:0001105	RNA polymerase II transcription coactivator activity
0.56	GO:0001102	RNA polymerase II activating transcription factor binding
0.56	GO:0035326	enhancer binding
0.55	GO:1990841	promoter-specific chromatin binding
0.53	GO:0046872	metal ion binding
0.49	GO:0003690	double-stranded DNA binding
0.40	GO:0016922	ligand-dependent nuclear receptor binding
0.40	GO:0030331	estrogen receptor binding

0.61	GO:0005634	nucleus
0.47	GO:0070013	intracellular organelle lumen
0.43	GO:0044446	intracellular organelle part
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1FX20|T1FX20_HELRO
Uncharacterized protein
Search

0.72	GO:0006470	protein dephosphorylation
0.54	GO:0000188	inactivation of MAPK activity
0.46	GO:0043622	cortical microtubule organization
0.44	GO:0009737	response to abscisic acid
0.41	GO:0030036	actin cytoskeleton organization
0.37	GO:0055002	striated muscle cell development
0.37	GO:0010927	cellular component assembly involved in morphogenesis
0.36	GO:0016310	phosphorylation
0.36	GO:0070925	organelle assembly

0.79	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.66	GO:0004725	protein tyrosine phosphatase activity
0.54	GO:0033549	MAP kinase phosphatase activity
0.37	GO:0016301	kinase activity

0.30

GO:0016020

membrane

0.79

GO:0008138

tr|T1FX21|T1FX21_HELRO
Uncharacterized protein
Search

MAEA

0.89	Macrophage erythroblast attacher

0.85	GO:0045721	negative regulation of gluconeogenesis
0.48	GO:0048821	erythrocyte development
0.47	GO:0043066	negative regulation of apoptotic process
0.47	GO:0043353	enucleate erythrocyte differentiation
0.46	GO:0033032	regulation of myeloid cell apoptotic process
0.45	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.44	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.42	GO:0071695	anatomical structure maturation
0.42	GO:0048469	cell maturation
0.41	GO:0007155	cell adhesion

0.44	GO:0003779	actin binding
0.43	GO:0004842	ubiquitin-protein transferase activity
0.35	GO:0016874	ligase activity
0.33	GO:0043565	sequence-specific DNA binding
0.33	GO:0008270	zinc ion binding
0.33	GO:0003700	DNA binding transcription factor activity

0.48	GO:0034657	GID complex
0.47	GO:0016363	nuclear matrix
0.45	GO:0005826	actomyosin contractile ring
0.43	GO:0005819	spindle
0.41	GO:0005654	nucleoplasm
0.40	GO:0005887	integral component of plasma membrane

0.35	EC:6	GO:0016874
0.43	KEGG:R03876	GO:0004842

tr|T1FX22|T1FX22_HELRO
Uncharacterized protein
Search

AKAP17A

0.85	Akinase anchor protein 17Alike [Saccoglossus kowalevskii]

0.68	GO:0043484	regulation of RNA splicing
0.46	GO:0016310	phosphorylation
0.42	GO:0007411	axon guidance
0.34	GO:0042113	B cell activation
0.34	GO:0006606	protein import into nucleus
0.34	GO:0032259	methylation
0.34	GO:0008380	RNA splicing
0.33	GO:0006397	mRNA processing
0.33	GO:0006508	proteolysis
0.33	GO:0007165	signal transduction

0.71	GO:0051018	protein kinase A binding
0.48	GO:0016301	kinase activity
0.45	GO:0003676	nucleic acid binding
0.35	GO:0008171	O-methyltransferase activity
0.34	GO:0061608	nuclear import signal receptor activity
0.34	GO:0004252	serine-type endopeptidase activity

0.46	GO:0016607	nuclear speck
0.42	GO:0005829	cytosol
0.34	GO:0005681	spliceosomal complex
0.30	GO:0031224	intrinsic component of membrane

0.35

GO:0008171

tr|T1FX23|T1FX23_HELRO
Uncharacterized protein
Search

0.79	GO:0006002	fructose 6-phosphate metabolic process
0.78	GO:0061615	glycolytic process through fructose-6-phosphate
0.32	GO:0046835	carbohydrate phosphorylation

0.79	GO:0003872	6-phosphofructokinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0046872	metal ion binding
0.32	GO:0047334	diphosphate-fructose-6-phosphate 1-phosphotransferase activity

0.48	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.79

EC:2.7.1.11

GO:0003872

tr|T1FX24|T1FX24_HELRO
Uncharacterized protein
Search

0.54	Cyclin and CBS domain divalent metal cation transport mediator 2b

0.52	GO:0010960	magnesium ion homeostasis
0.49	GO:0070166	enamel mineralization
0.48	GO:1903830	magnesium ion transmembrane transport
0.48	GO:0035725	sodium ion transmembrane transport
0.46	GO:0060041	retina development in camera-type eye

0.48	GO:0015095	magnesium ion transmembrane transporter activity
0.47	GO:0015081	sodium ion transmembrane transporter activity

0.50	GO:0016323	basolateral plasma membrane
0.43	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

tr|T1FX25|T1FX25_HELRO
Uncharacterized protein
Search

APTX

0.74

Aprataxin

0.65	GO:0006281	DNA repair
0.64	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.50	GO:0042542	response to hydrogen peroxide
0.48	GO:0031647	regulation of protein stability
0.47	GO:0006266	DNA ligation
0.44	GO:0016311	dephosphorylation
0.33	GO:0000398	mRNA splicing, via spliceosome
0.32	GO:0006508	proteolysis

0.85	GO:0033699	DNA 5'-adenosine monophosphate hydrolase activity
0.55	GO:0003677	DNA binding
0.51	GO:0047485	protein N-terminus binding
0.50	GO:0051219	phosphoprotein binding
0.49	GO:0008967	phosphoglycolate phosphatase activity
0.48	GO:0003682	chromatin binding
0.47	GO:0003725	double-stranded RNA binding
0.47	GO:0120108	DNA-3'-diphospho-5'-guanosine diphosphatase
0.38	GO:0046403	polynucleotide 3'-phosphatase activity
0.36	GO:0046872	metal ion binding

0.48	GO:0005730	nucleolus
0.47	GO:0005654	nucleoplasm
0.47	GO:0000790	nuclear chromatin
0.34	GO:0071011	precatalytic spliceosome
0.32	GO:0005737	cytoplasm

0.49	EC:3.1.3.18	GO:0008967
0.49	KEGG:R01334	GO:0008967

tr|T1FX26|T1FX26_HELRO
Uncharacterized protein
Search

0.39	Neutral and basic amino acid transport protein rBAT

0.60	GO:0005975	carbohydrate metabolic process
0.42	GO:0044248	cellular catabolic process
0.42	GO:1901575	organic substance catabolic process
0.32	GO:0044281	small molecule metabolic process

0.51	GO:0008788	alpha,alpha-phosphotrehalase activity
0.43	GO:0090599	alpha-glucosidase activity
0.37	GO:0004556	alpha-amylase activity
0.37	GO:0103025	alpha-amylase activity (releasing maltohexaose)
0.36	GO:0043896	glucan 1,6-alpha-glucosidase activity
0.34	GO:0004565	beta-galactosidase activity
0.33	GO:0043169	cation binding
0.32	GO:0016829	lyase activity

0.38	GO:0031526	brush border membrane
0.37	GO:0005737	cytoplasm
0.35	GO:0019866	organelle inner membrane
0.34	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.51

EC:3.2.1.93

GO:0008788

tr|T1FX27|T1FX27_HELRO
Uncharacterized protein
Search

SPSB4

0.86	SPRY domain-containing SOCS box protein 1

0.60	GO:0035556	intracellular signal transduction
0.50	GO:0007280	pole cell migration
0.49	GO:0035017	cuticle pattern formation
0.49	GO:0046843	dorsal appendage formation
0.49	GO:0007315	pole plasm assembly
0.47	GO:0007472	wing disc morphogenesis
0.46	GO:0045732	positive regulation of protein catabolic process
0.41	GO:0008104	protein localization
0.35	GO:0006465	signal peptide processing
0.33	GO:0055114	oxidation-reduction process

0.35	GO:0005544	calcium-dependent phospholipid binding
0.35	GO:0030246	carbohydrate binding
0.35	GO:0004488	methylenetetrahydrofolate dehydrogenase (NADP+) activity
0.34	GO:0005509	calcium ion binding
0.34	GO:0005515	protein binding
0.34	GO:0008233	peptidase activity

0.49	GO:0031466	Cul5-RING ubiquitin ligase complex
0.48	GO:0045495	pole plasm
0.48	GO:0070449	elongin complex
0.46	GO:0048471	perinuclear region of cytoplasm
0.45	GO:0005938	cell cortex
0.36	GO:0005787	signal peptidase complex
0.30	GO:0016021	integral component of membrane

0.35	EC:1.5.1.5	GO:0004488
0.35	KEGG:R01220	GO:0004488

tr|T1FX28|T1FX28_HELRO
Uncharacterized protein
Search

0.20	Hematopoietic prostaglandin D synthase

0.72	GO:0006692	prostanoid metabolic process
0.61	GO:2000255	negative regulation of male germ cell proliferation
0.47	GO:1901685	glutathione derivative metabolic process
0.44	GO:0019369	arachidonic acid metabolic process
0.44	GO:0046456	icosanoid biosynthetic process
0.44	GO:0006636	unsaturated fatty acid biosynthetic process
0.43	GO:0007626	locomotory behavior
0.39	GO:0044272	sulfur compound biosynthetic process
0.38	GO:0007165	signal transduction
0.36	GO:1901566	organonitrogen compound biosynthetic process

0.78	GO:0004667	prostaglandin-D synthase activity
0.64	GO:0042803	protein homodimerization activity
0.60	GO:0005509	calcium ion binding
0.56	GO:0000287	magnesium ion binding
0.47	GO:0016740	transferase activity

0.40

GO:0005829

cytosol

0.78	EC:5.3.99.2	GO:0004667
0.78	KEGG:R02266	GO:0004667

tr|T1FX29|T1FX29_HELRO
Uncharacterized protein
Search

0.45	Progestin and adipoQ receptor family member VII, a

0.30

GO:0044425

membrane part

tr|T1FX30|T1FX30_HELRO
Uncharacterized protein
Search

0.80	Tubulin polymerization-promoting protein homolog

0.67	GO:0001578	microtubule bundle formation
0.66	GO:0046785	microtubule polymerization
0.43	GO:0048675	axon extension
0.35	GO:0035556	intracellular signal transduction

0.64	GO:0015631	tubulin binding
0.56	GO:0005509	calcium ion binding

0.42

GO:0005829

cytosol

tr|T1FX31|T1FX31_HELRO
Phosphodiesterase
Search

0.55	Phosphodiesterase

0.60	GO:0007165	signal transduction
0.42	GO:0048793	pronephros development
0.34	GO:0010754	negative regulation of cGMP-mediated signaling
0.34	GO:0090038	negative regulation of protein kinase C signaling
0.34	GO:0046069	cGMP catabolic process
0.34	GO:0032528	microvillus organization
0.34	GO:0010446	response to alkaline pH
0.34	GO:0007635	chemosensory behavior
0.34	GO:0008340	determination of adult lifespan
0.34	GO:0042542	response to hydrogen peroxide

0.79	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.53	GO:0046872	metal ion binding
0.33	GO:0005516	calmodulin binding

0.30

GO:0016020

membrane

0.79

EC:3.1.4.17

GO:0004114

tr|T1FX32|T1FX32_HELRO
Acylphosphatase
Search

ACYP1

0.54	Acylphosphatase

0.35	GO:0007131	reciprocal meiotic recombination
0.34	GO:0006298	mismatch repair
0.34	GO:0051693	actin filament capping
0.33	GO:0007010	cytoskeleton organization
0.32	GO:0016310	phosphorylation

0.81	GO:0003998	acylphosphatase activity
0.33	GO:0030983	mismatched DNA binding
0.33	GO:0005200	structural constituent of cytoskeleton
0.33	GO:0005543	phospholipid binding
0.33	GO:0003779	actin binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0016301	kinase activity

0.35	GO:0032300	mismatch repair complex
0.34	GO:0008091	spectrin
0.34	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.81

EC:3.6.1.7

GO:0003998

tr|T1FX33|T1FX33_HELRO
Uncharacterized protein
Search

LAMB2

0.66	Laminin subunit beta-2

0.68	GO:0070831	basement membrane assembly
0.63	GO:0016203	muscle attachment
0.63	GO:0009790	embryo development
0.63	GO:0009888	tissue development
0.55	GO:0034446	substrate adhesion-dependent cell spreading
0.52	GO:0021812	neuronal-glial interaction involved in cerebral cortex radial glia guided migration
0.51	GO:0009887	animal organ morphogenesis
0.48	GO:0031175	neuron projection development
0.47	GO:0040017	positive regulation of locomotion
0.47	GO:0033627	cell adhesion mediated by integrin

0.50	GO:0003944	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase activity
0.47	GO:0005201	extracellular matrix structural constituent
0.45	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.41	GO:0003747	translation release factor activity
0.39	GO:0005230	extracellular ligand-gated ion channel activity
0.39	GO:0005178	integrin binding

0.57	GO:0005605	basal lamina
0.46	GO:0005615	extracellular space
0.41	GO:0043234	protein complex
0.40	GO:0043083	synaptic cleft
0.35	GO:0005886	plasma membrane
0.35	GO:1903561	extracellular vesicle
0.30	GO:0016021	integral component of membrane

0.50

EC:3.1.4.45

GO:0003944

tr|T1FX34|T1FX34_HELRO
Uncharacterized protein
Search

tr|T1FX35|T1FX35_HELRO
Uncharacterized protein
Search

0.60	Cdk5 and Abl enzyme substrate 1

0.73	GO:0051726	regulation of cell cycle
0.43	GO:0048731	system development
0.42	GO:0035120	post-embryonic appendage morphogenesis
0.42	GO:0035114	imaginal disc-derived appendage morphogenesis
0.41	GO:0048707	instar larval or pupal morphogenesis
0.41	GO:0007552	metamorphosis
0.41	GO:0060562	epithelial tube morphogenesis
0.40	GO:0090066	regulation of anatomical structure size
0.33	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing
0.33	GO:0000082	G1/S transition of mitotic cell cycle

0.33	GO:0003735	structural constituent of ribosome
0.33	GO:0005515	protein binding
0.32	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.32	GO:0004519	endonuclease activity
0.32	GO:0020037	heme binding
0.32	GO:0005506	iron ion binding

0.40	GO:0005829	cytosol
0.33	GO:0030426	growth cone
0.33	GO:0005634	nucleus
0.33	GO:0005840	ribosome
0.32	GO:0031974	membrane-enclosed lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.32

GO:0016705

tr|T1FX36|T1FX36_HELRO
Uncharacterized protein
Search

PDS5A

0.91	Sister chromatid cohesion protein PDS5 like protein A

0.76	GO:0007064	mitotic sister chromatid cohesion
0.74	GO:0008156	negative regulation of DNA replication
0.55	GO:0061774	cohesin unloading
0.53	GO:0030717	karyosome formation
0.48	GO:0006281	DNA repair
0.43	GO:0051301	cell division
0.34	GO:0055114	oxidation-reduction process

0.38	GO:0005515	protein binding
0.36	GO:0051287	NAD binding
0.36	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

0.67	GO:0000785	chromatin
0.63	GO:0005654	nucleoplasm
0.51	GO:0005886	plasma membrane
0.51	GO:0005700	polytene chromosome
0.38	GO:0000775	chromosome, centromeric region
0.36	GO:0005829	cytosol

0.36

EC:1.1.1

GO:0016616

tr|T1FX37|T1FX37_HELRO
Uncharacterized protein
Search

0.53	GO:0032836	glomerular basement membrane development
0.43	GO:0007155	cell adhesion
0.40	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.38	GO:0061304	retinal blood vessel morphogenesis
0.38	GO:0052548	regulation of endopeptidase activity
0.38	GO:0001569	branching involved in blood vessel morphogenesis
0.38	GO:0071711	basement membrane organization
0.38	GO:0061333	renal tubule morphogenesis
0.38	GO:0007528	neuromuscular junction development
0.37	GO:0072577	endothelial cell apoptotic process

0.76	GO:0005201	extracellular matrix structural constituent
0.38	GO:0048407	platelet-derived growth factor binding
0.37	GO:0005178	integrin binding
0.36	GO:0004867	serine-type endopeptidase inhibitor activity
0.35	GO:0004222	metalloendopeptidase activity
0.33	GO:0003677	DNA binding

0.74	GO:0005581	collagen trimer
0.72	GO:0005604	basement membrane
0.55	GO:0098645	collagen network
0.36	GO:0005615	extracellular space
0.35	GO:0005829	cytosol
0.35	GO:0005783	endoplasmic reticulum
0.30	GO:0016020	membrane

0.35

GO:0004222

tr|T1FX38|T1FX38_HELRO
Uncharacterized protein
Search

0.72	5'-AMP-activated protein kinase subunit gamma-1

0.53	GO:0016310	phosphorylation
0.49	GO:0042595	behavioral response to starvation
0.49	GO:0030730	sequestering of triglyceride
0.47	GO:0042632	cholesterol homeostasis
0.45	GO:0045787	positive regulation of cell cycle
0.45	GO:0009267	cellular response to starvation
0.45	GO:0006914	autophagy
0.40	GO:0006629	lipid metabolic process
0.37	GO:0010628	positive regulation of gene expression
0.36	GO:0051170	nuclear import

0.55	GO:0016301	kinase activity
0.44	GO:0019901	protein kinase binding
0.36	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.35	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.34	GO:0044212	transcription regulatory region DNA binding
0.33	GO:0003746	translation elongation factor activity
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.33	GO:0046872	metal ion binding

0.41	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm
0.35	GO:0034708	methyltransferase complex
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.35

GO:0016773

tr|T1FX39|T1FX39_HELRO
Uncharacterized protein
Search

0.41	F-box/WD repeat-containing protein 7

0.55	GO:0006468	protein phosphorylation
0.42	GO:0000132	establishment of mitotic spindle orientation
0.39	GO:0006364	rRNA processing
0.39	GO:0071276	cellular response to cadmium ion
0.38	GO:0051301	cell division
0.36	GO:0007165	signal transduction
0.36	GO:0006508	proteolysis
0.35	GO:2001125	negative regulation of translational frameshifting
0.35	GO:1902660	negative regulation of glucose mediated signaling pathway
0.35	GO:0032995	regulation of fungal-type cell wall biogenesis

0.60	GO:0004674	protein serine/threonine kinase activity
0.48	GO:0030554	adenyl nucleotide binding
0.48	GO:0097367	carbohydrate derivative binding
0.48	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0008144	drug binding
0.44	GO:0005515	protein binding
0.39	GO:0044877	macromolecular complex binding
0.38	GO:0060090	molecular adaptor activity
0.37	GO:0003924	GTPase activity
0.37	GO:0019001	guanyl nucleotide binding

0.40	GO:0000922	spindle pole
0.40	GO:0005875	microtubule associated complex
0.39	GO:0005874	microtubule
0.39	GO:0019005	SCF ubiquitin ligase complex
0.34	GO:0005737	cytoplasm
0.34	GO:0000152	nuclear ubiquitin ligase complex
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0005730	nucleolus
0.33	GO:0019013	viral nucleocapsid
0.30	GO:0016020	membrane

0.60

GO:0004674

tr|T1FX40|T1FX40_HELRO
Uncharacterized protein
Search

0.10	Putative very low-density lipoprotein receptor

0.53	GO:0006898	receptor-mediated endocytosis
0.51	GO:0034436	glycoprotein transport
0.51	GO:0034447	very-low-density lipoprotein particle clearance
0.49	GO:0038026	reelin-mediated signaling pathway
0.48	GO:1900006	positive regulation of dendrite development
0.48	GO:0021517	ventral spinal cord development
0.48	GO:0048813	dendrite morphogenesis
0.46	GO:0045860	positive regulation of protein kinase activity
0.45	GO:0000122	negative regulation of transcription by RNA polymerase II
0.37	GO:0006508	proteolysis

0.63	GO:0005509	calcium ion binding
0.61	GO:0030228	lipoprotein particle receptor activity
0.51	GO:0038025	reelin receptor activity
0.51	GO:0034437	glycoprotein transporter activity
0.51	GO:0034189	very-low-density lipoprotein particle binding
0.50	GO:0034185	apolipoprotein binding
0.48	GO:0048306	calcium-dependent protein binding
0.39	GO:0004252	serine-type endopeptidase activity
0.37	GO:0071936	coreceptor activity involved in Wnt signaling pathway
0.36	GO:0017147	Wnt-protein binding

0.47	GO:0043235	receptor complex
0.44	GO:0005615	extracellular space
0.38	GO:0005794	Golgi apparatus
0.37	GO:0098589	membrane region
0.36	GO:1990851	Wnt-Frizzled-LRP5/6 complex
0.36	GO:1990909	Wnt signalosome
0.36	GO:1990777	lipoprotein particle
0.36	GO:0098590	plasma membrane region
0.35	GO:0005765	lysosomal membrane
0.35	GO:0043025	neuronal cell body

0.39

GO:0004252

tr|T1FX41|T1FX41_HELRO
Uncharacterized protein
Search

PYROXD1

0.83	Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1

0.51	GO:0055114	oxidation-reduction process
0.49	GO:0034599	cellular response to oxidative stress

0.52	GO:0016491	oxidoreductase activity
0.33	GO:0005515	protein binding

0.52	GO:0030017	sarcomere
0.44	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.52

GO:0016491

tr|T1FX42|T1FX42_HELRO
Uncharacterized protein
Search

0.70	Helix-loop-helix DNA-binding domain protein (Fragment)

0.77	GO:0001708	cell fate specification
0.74	GO:0007417	central nervous system development
0.73	GO:0030182	neuron differentiation
0.65	GO:0021781	glial cell fate commitment
0.62	GO:0042552	myelination
0.62	GO:0048513	animal organ development
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:2001141	regulation of RNA biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.50	GO:0050767	regulation of neurogenesis

0.68	GO:0046983	protein dimerization activity
0.50	GO:0140110	transcription regulator activity
0.47	GO:0071837	HMG box domain binding
0.42	GO:0042802	identical protein binding
0.36	GO:0003677	DNA binding
0.35	GO:0052856	NADHX epimerase activity
0.33	GO:0004534	5'-3' exoribonuclease activity
0.32	GO:0046872	metal ion binding
0.32	GO:1901265	nucleoside phosphate binding
0.32	GO:0036094	small molecule binding

0.39	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm
0.33	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

0.35

EC:5.1

GO:0052856

tr|T1FX43|T1FX43_HELRO
Uncharacterized protein
Search

tr|T1FX44|T1FX44_HELRO
Uncharacterized protein
Search

0.86	50 kDa hatching enzyme

0.61	GO:0006508	proteolysis
0.40	GO:0000003	reproduction
0.37	GO:0030574	collagen catabolic process
0.35	GO:0006954	inflammatory response
0.34	GO:0016567	protein ubiquitination

0.70	GO:0004222	metalloendopeptidase activity
0.63	GO:0008270	zinc ion binding
0.34	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0016874	ligase activity

0.74	GO:0031012	extracellular matrix
0.35	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.70	EC:3.4.24	GO:0004222
0.34	KEGG:R03876	GO:0004842

tr|T1FX45|T1FX45_HELRO
Uncharacterized protein
Search

tr|T1FX46|T1FX46_HELRO
Uncharacterized protein
Search

tr|T1FX47|T1FX47_HELRO
Uncharacterized protein
Search

THUMPD3

0.85	THUMP domain-containing protein 3

0.42	GO:0030488	tRNA methylation
0.34	GO:0045892	negative regulation of transcription, DNA-templated

0.58	GO:0003723	RNA binding
0.42	GO:0016423	tRNA (guanine) methyltransferase activity

0.50	GO:0005730	nucleolus
0.48	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.42

GO:0016423

tr|T1FX48|T1FX48_HELRO
Uncharacterized protein
Search

0.83	SRY-box containing transcription factor 7 (Fragment)

0.50	GO:0007275	multicellular organism development
0.47	GO:0000122	negative regulation of transcription by RNA polymerase II
0.46	GO:0009888	tissue development
0.46	GO:0009653	anatomical structure morphogenesis
0.46	GO:0042127	regulation of cell proliferation
0.45	GO:0030154	cell differentiation
0.44	GO:0042789	mRNA transcription by RNA polymerase II
0.43	GO:0042662	negative regulation of mesodermal cell fate specification
0.43	GO:2000043	regulation of cardiac cell fate specification
0.43	GO:0003308	negative regulation of Wnt signaling pathway involved in heart development

0.55	GO:0003677	DNA binding
0.43	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.42	GO:0008013	beta-catenin binding
0.42	GO:0001067	regulatory region nucleic acid binding
0.42	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.40	GO:0046982	protein heterodimerization activity
0.40	GO:0003713	transcription coactivator activity
0.40	GO:0008134	transcription factor binding
0.35	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.41	GO:0005667	transcription factor complex
0.37	GO:0044446	intracellular organelle part
0.34	GO:0005694	chromosome
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0005737	cytoplasm

tr|T1FX49|T1FX49_HELRO
Uncharacterized protein
Search

MMACHC

0.97	Methylmalonic aciduria and homocystinuria type C

0.71	GO:0070988	demethylation
0.67	GO:0006749	glutathione metabolic process
0.63	GO:0009236	cobalamin biosynthetic process
0.48	GO:0055114	oxidation-reduction process
0.47	GO:0000122	negative regulation of transcription by RNA polymerase II
0.44	GO:0006457	protein folding

0.83	GO:0033787	cyanocobalamin reductase (cyanide-eliminating) activity
0.75	GO:0043295	glutathione binding
0.74	GO:0032451	demethylase activity
0.65	GO:0071949	FAD binding
0.62	GO:0042803	protein homodimerization activity
0.50	GO:0001106	RNA polymerase II transcription corepressor activity
0.45	GO:0051082	unfolded protein binding

0.52	GO:0005739	mitochondrion
0.48	GO:0016272	prefoldin complex
0.30	GO:0016020	membrane

0.83	EC:1.16.1.6	GO:0033787
0.83	KEGG:R02999	GO:0033787

tr|T1FX50|T1FX50_HELRO
Purple acid phosphatase
Search

0.57	Purple acid phosphatase

0.67	GO:0016311	dephosphorylation
0.33	GO:0007018	microtubule-based movement

0.78	GO:0003993	acid phosphatase activity
0.53	GO:0046872	metal ion binding
0.33	GO:0003777	microtubule motor activity
0.32	GO:0016887	ATPase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.34	GO:0005576	extracellular region
0.34	GO:0030286	dynein complex
0.30	GO:0031224	intrinsic component of membrane

0.78

EC:3.1.3.2

GO:0003993

tr|T1FX51|T1FX51_HELRO
Uncharacterized protein
Search

HSPA4L

0.71	Polo-like kinase 4 (Drosophila)

0.85	GO:0007099	centriole replication
0.69	GO:0046601	positive regulation of centriole replication
0.66	GO:0098535	de novo centriole assembly involved in multi-ciliated epithelial cell differentiation
0.63	GO:0006468	protein phosphorylation
0.62	GO:0060707	trophoblast giant cell differentiation

0.70	GO:0004674	protein serine/threonine kinase activity
0.57	GO:0042802	identical protein binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.83	GO:0005814	centriole
0.66	GO:0098536	deuterosome
0.63	GO:0001741	XY body
0.59	GO:0005813	centrosome
0.56	GO:0005730	nucleolus
0.53	GO:0005829	cytosol

0.70

GO:0004674

tr|T1FX52|T1FX52_HELRO
Uncharacterized protein
Search

0.44	Membrane-associated tyrosine-and threonine-specific cdc2-inhibitory kinase

0.63	GO:0006468	protein phosphorylation
0.38	GO:0090485	chromosome number maintenance
0.38	GO:0002119	nematode larval development
0.38	GO:0019220	regulation of phosphate metabolic process
0.38	GO:1904145	negative regulation of meiotic cell cycle process involved in oocyte maturation
0.38	GO:0051078	meiotic nuclear envelope disassembly
0.37	GO:0060280	negative regulation of ovulation
0.37	GO:0010563	negative regulation of phosphorus metabolic process
0.37	GO:0050790	regulation of catalytic activity
0.37	GO:0048477	oogenesis

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity
0.34	GO:0005057	signal transducer activity, downstream of receptor
0.33	GO:0046872	metal ion binding

0.37	GO:0005794	Golgi apparatus
0.36	GO:0097038	perinuclear endoplasmic reticulum
0.36	GO:0044428	nuclear part
0.35	GO:0000793	condensed chromosome
0.35	GO:0098588	bounding membrane of organelle
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0031984	organelle subcompartment
0.34	GO:0019898	extrinsic component of membrane
0.34	GO:0031967	organelle envelope
0.33	GO:0005886	plasma membrane

tr|T1FX53|T1FX53_HELRO
Uncharacterized protein
Search

tr|T1FX54|T1FX54_HELRO
Uncharacterized protein
Search

0.36	GO:0016310	phosphorylation
0.33	GO:0006464	cellular protein modification process

0.68	GO:0046983	protein dimerization activity
0.36	GO:0016301	kinase activity
0.33	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.33	GO:0140096	catalytic activity, acting on a protein
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0044425

membrane part

0.33

GO:0016773

tr|T1FX55|T1FX55_HELRO
Uncharacterized protein
Search

0.30

GO:0044425

membrane part

tr|T1FX56|T1FX56_HELRO
Uncharacterized protein
Search

0.79	Putative syntaxin-binding protein 2 (Fragment)

0.37	GO:0006904	vesicle docking involved in exocytosis
0.36	GO:0060271	cilium assembly
0.35	GO:0043044	ATP-dependent chromatin remodeling
0.35	GO:0007018	microtubule-based movement
0.35	GO:0034765	regulation of ion transmembrane transport
0.35	GO:0070588	calcium ion transmembrane transport
0.35	GO:0001578	microtubule bundle formation
0.35	GO:0016569	covalent chromatin modification
0.34	GO:0031503	protein complex localization
0.34	GO:0030705	cytoskeleton-dependent intracellular transport

0.36	GO:0005245	voltage-gated calcium channel activity
0.36	GO:0031491	nucleosome binding
0.35	GO:0045503	dynein light chain binding
0.35	GO:0051959	dynein light intermediate chain binding
0.35	GO:0008569	ATP-dependent microtubule motor activity, minus-end-directed
0.35	GO:0045505	dynein intermediate chain binding
0.34	GO:0046875	ephrin receptor binding
0.34	GO:0004386	helicase activity
0.34	GO:0004333	fumarate hydratase activity
0.34	GO:0004731	purine-nucleoside phosphorylase activity

0.36	GO:0016589	NURF complex
0.36	GO:0005929	cilium
0.36	GO:0005891	voltage-gated calcium channel complex
0.35	GO:0032838	plasma membrane bounded cell projection cytoplasm
0.34	GO:0030992	intraciliary transport particle B
0.34	GO:0030286	dynein complex
0.34	GO:0045239	tricarboxylic acid cycle enzyme complex
0.33	GO:0005576	extracellular region
0.33	GO:0005739	mitochondrion

0.35	EC:3.6.4.5	GO:0008569
0.34	KEGG:R01082	GO:0004333

tr|T1FX57|T1FX57_HELRO
Uncharacterized protein
Search

0.63	YTH domain family protein 2 (Fragment)

0.51	GO:0061157	mRNA destabilization
0.49	GO:1903538	regulation of meiotic cell cycle process involved in oocyte maturation
0.48	GO:1903679	positive regulation of cap-independent translational initiation
0.48	GO:0001556	oocyte maturation
0.47	GO:0098508	endothelial to hematopoietic transition
0.46	GO:1902036	regulation of hematopoietic stem cell differentiation
0.45	GO:0045746	negative regulation of Notch signaling pathway
0.43	GO:0048598	embryonic morphogenesis
0.40	GO:0006402	mRNA catabolic process
0.34	GO:0006959	humoral immune response

0.59	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.45	GO:0000932	P-body
0.42	GO:0005815	microtubule organizing center
0.42	GO:0005829	cytosol
0.40	GO:0005634	nucleus

tr|T1FX58|T1FX58_HELRO
Uncharacterized protein
Search

0.79	RNA-binding protein Elav1

0.40	GO:0051239	regulation of multicellular organismal process
0.39	GO:0050793	regulation of developmental process
0.39	GO:0048856	anatomical structure development
0.39	GO:0032501	multicellular organismal process
0.38	GO:0048518	positive regulation of biological process
0.38	GO:0030154	cell differentiation
0.37	GO:0043489	RNA stabilization
0.37	GO:0008298	intracellular mRNA localization
0.37	GO:0043488	regulation of mRNA stability
0.36	GO:1903312	negative regulation of mRNA metabolic process

0.59	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.36	GO:0005938	cell cortex
0.35	GO:0005634	nucleus
0.35	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0019013	viral nucleocapsid
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

tr|T1FX59|T1FX59_HELRO
Uncharacterized protein
Search

0.45	GO:0016348	imaginal disc-derived leg joint morphogenesis
0.45	GO:0007366	periodic partitioning by pair rule gene
0.43	GO:0007443	Malpighian tubule morphogenesis
0.41	GO:0000122	negative regulation of transcription by RNA polymerase II
0.40	GO:0045944	positive regulation of transcription by RNA polymerase II
0.37	GO:0060216	definitive hemopoiesis
0.34	GO:0006351	transcription, DNA-templated

0.51	GO:0003676	nucleic acid binding
0.36	GO:0046872	metal ion binding
0.35	GO:0003700	DNA binding transcription factor activity
0.32	GO:0005515	protein binding

0.37	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|T1FX60|T1FX60_HELRO
Uncharacterized protein
Search

0.57	GO:0019752	carboxylic acid metabolic process
0.45	GO:0042136	neurotransmitter biosynthetic process
0.39	GO:0016053	organic acid biosynthetic process
0.37	GO:1901564	organonitrogen compound metabolic process
0.36	GO:0042493	response to drug
0.36	GO:0016054	organic acid catabolic process
0.35	GO:0007268	chemical synaptic transmission
0.34	GO:0017144	drug metabolic process
0.34	GO:0035641	locomotory exploration behavior
0.34	GO:0035176	social behavior

0.68	GO:0016831	carboxy-lyase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.40	GO:0016595	glutamate binding
0.37	GO:0046982	protein heterodimerization activity
0.34	GO:0047485	protein N-terminus binding
0.33	GO:0004673	protein histidine kinase activity
0.32	GO:0004871	signal transducer activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.47	GO:0030424	axon
0.46	GO:0045202	synapse
0.38	GO:0099501	exocytic vesicle membrane
0.37	GO:0031225	anchored component of membrane
0.37	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0005829	cytosol
0.37	GO:0098590	plasma membrane region
0.36	GO:0030054	cell junction
0.36	GO:0000139	Golgi membrane
0.35	GO:0061200	clathrin-sculpted gamma-aminobutyric acid transport vesicle

0.68

EC:4.1.1

GO:0016831

tr|T1FX61|T1FX61_HELRO
Uncharacterized protein
Search

0.68

GO:0046983

protein dimerization activity

tr|T1FX62|T1FX62_HELRO
Uncharacterized protein
Search

SLC35E3

0.95	Siah E3 ubiquitin protein ligase family member 3

0.30

GO:0044425

membrane part

tr|T1FX63|T1FX63_HELRO
Uncharacterized protein
Search

0.51	Cation efflux protein/ zinc transporter

0.61	GO:0098655	cation transmembrane transport
0.47	GO:0010043	response to zinc ion
0.43	GO:0097501	stress response to metal ion
0.42	GO:0061088	regulation of sequestering of zinc ion
0.41	GO:0006829	zinc II ion transport
0.39	GO:0098754	detoxification
0.37	GO:0032119	sequestering of zinc ion
0.37	GO:0098660	inorganic ion transmembrane transport
0.32	GO:0055114	oxidation-reduction process
0.32	GO:1903506	regulation of nucleic acid-templated transcription

0.61	GO:0008324	cation transmembrane transporter activity
0.37	GO:0015318	inorganic molecular entity transmembrane transporter activity
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.32	GO:0003700	DNA binding transcription factor activity

0.43	GO:0005794	Golgi apparatus
0.42	GO:0016323	basolateral plasma membrane
0.36	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0031410	cytoplasmic vesicle
0.34	GO:0032040	small-subunit processome
0.32	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.34

GO:0032440

tr|T1FX64|T1FX64_HELRO
Uncharacterized protein
Search

tr|T1FX65|T1FX65_HELRO
Uncharacterized protein
Search

0.10	Zinc finger MYM-type protein 1

0.37	GO:0016310	phosphorylation
0.36	GO:0006357	regulation of transcription by RNA polymerase II
0.34	GO:0006310	DNA recombination
0.34	GO:0000723	telomere maintenance
0.34	GO:0032196	transposition
0.33	GO:0032392	DNA geometric change
0.33	GO:0015074	DNA integration
0.33	GO:0006281	DNA repair
0.32	GO:0055114	oxidation-reduction process

0.68	GO:0046983	protein dimerization activity
0.37	GO:0016301	kinase activity
0.36	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.34	GO:0003677	DNA binding
0.34	GO:0140097	catalytic activity, acting on DNA
0.34	GO:0019901	protein kinase binding
0.33	GO:0004386	helicase activity
0.33	GO:0043168	anion binding
0.33	GO:1901265	nucleoside phosphate binding
0.33	GO:0042578	phosphoric ester hydrolase activity

0.36	GO:0005654	nucleoplasm
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.33

GO:0042578

tr|T1FX66|T1FX66_HELRO
Uncharacterized protein
Search

0.43	GO:0040034	regulation of development, heterochronic
0.43	GO:1903506	regulation of nucleic acid-templated transcription
0.43	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.43	GO:0010468	regulation of gene expression

0.51	GO:0003676	nucleic acid binding
0.40	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.37	GO:0004386	helicase activity
0.35	GO:0046872	metal ion binding

0.46	GO:0005634	nucleus
0.30	GO:0044425	membrane part

tr|T1FX67|T1FX67_HELRO
Uncharacterized protein
Search

UBFD1

0.93	To Ubiquitin domain-containing protein UBFD1

0.45	GO:0006508	proteolysis
0.39	GO:0006397	mRNA processing
0.39	GO:0090501	RNA phosphodiester bond hydrolysis
0.38	GO:0006468	protein phosphorylation

0.72	GO:0045296	cadherin binding
0.45	GO:0008233	peptidase activity
0.39	GO:0004540	ribonuclease activity
0.39	GO:0003723	RNA binding
0.38	GO:0004672	protein kinase activity
0.36	GO:0030554	adenyl nucleotide binding
0.36	GO:0097367	carbohydrate derivative binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0008144	drug binding

0.45

GO:0008233

tr|T1FX68|T1FX68_HELRO
Uncharacterized protein
Search

0.10	Putative E3 ubiquitin-protein ligase UBR7

0.35

GO:0016567

protein ubiquitination

0.63	GO:0008270	zinc ion binding
0.48	GO:0016874	ligase activity
0.33	GO:0016740	transferase activity

0.30

GO:0031224

intrinsic component of membrane

0.48

GO:0016874

tr|T1FX69|T1FX69_HELRO
Uncharacterized protein
Search

0.63	GO:1904158	axonemal central apparatus assembly
0.61	GO:0060438	trachea development
0.60	GO:0021591	ventricular system development
0.58	GO:0003341	cilium movement
0.58	GO:0010469	regulation of receptor activity
0.57	GO:0002064	epithelial cell development

0.60	GO:0005179	hormone activity
0.52	GO:0030976	thiamine pyrophosphate binding
0.48	GO:0000287	magnesium ion binding

0.65	GO:1990718	axonemal central pair projection
0.52	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

tr|T1FX70|T1FX70_HELRO
Uncharacterized protein
Search

0.76	GO:0051262	protein tetramerization
0.60	GO:0034220	ion transmembrane transport
0.44	GO:0010960	magnesium ion homeostasis
0.44	GO:0055069	zinc ion homeostasis
0.42	GO:0016049	cell growth
0.41	GO:0007005	mitochondrion organization
0.41	GO:0070838	divalent metal ion transport
0.39	GO:0016048	detection of temperature stimulus
0.39	GO:0050951	sensory perception of temperature stimulus
0.35	GO:0043052	thermotaxis

0.70	GO:0005216	ion channel activity
0.42	GO:0022836	gated channel activity
0.39	GO:0046873	metal ion transmembrane transporter activity

0.41

GO:0034703

cation channel complex

tr|T1FX71|T1FX71_HELRO
Uncharacterized protein
Search

SEC61G

0.95	Transport protein Sec61 subunit gamma

0.71	GO:0006605	protein targeting
0.70	GO:0071806	protein transmembrane transport
0.41	GO:0072599	establishment of protein localization to endoplasmic reticulum
0.39	GO:0001555	oocyte growth
0.38	GO:0030728	ovulation
0.36	GO:0010507	negative regulation of autophagy
0.35	GO:0036498	IRE1-mediated unfolded protein response
0.35	GO:0016310	phosphorylation
0.34	GO:0006695	cholesterol biosynthetic process
0.34	GO:0022406	membrane docking

0.75	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
0.35	GO:0016301	kinase activity
0.34	GO:0005543	phospholipid binding
0.33	GO:0016776	phosphotransferase activity, phosphate group as acceptor
0.33	GO:0005515	protein binding

0.45	GO:0005622	intracellular
0.41	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.37	GO:0044422	organelle part
0.37	GO:0043227	membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:2.7.4

GO:0016776

tr|T1FX72|T1FX72_HELRO
Uncharacterized protein
Search

0.24	Zinc finger MYM-type protein 1

0.68

GO:0046983

protein dimerization activity

tr|T1FX73|T1FX73_HELRO
Guanylate cyclase
Search

0.40	Guanylate cyclase

0.80	GO:0006182	cGMP biosynthetic process
0.62	GO:0006468	protein phosphorylation
0.61	GO:0035556	intracellular signal transduction
0.38	GO:0035845	photoreceptor cell outer segment organization
0.38	GO:0007601	visual perception
0.35	GO:0050962	detection of light stimulus involved in sensory perception
0.34	GO:0009584	detection of visible light
0.34	GO:0035725	sodium ion transmembrane transport
0.34	GO:0018212	peptidyl-tyrosine modification

0.80	GO:0004383	guanylate cyclase activity
0.62	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0004016	adenylate cyclase activity
0.34	GO:0005272	sodium channel activity
0.33	GO:0099600	transmembrane receptor activity
0.33	GO:0038023	signaling receptor activity

0.44	GO:0005622	intracellular
0.37	GO:0043234	protein complex
0.36	GO:0005886	plasma membrane
0.34	GO:0009986	cell surface
0.34	GO:0098552	side of membrane
0.30	GO:0016021	integral component of membrane

0.80

EC:4.6.1.2

GO:0004383

tr|T1FX74|T1FX74_HELRO
Uncharacterized protein
Search

0.75	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.43	GO:1902680	positive regulation of RNA biosynthetic process
0.42	GO:1902679	negative regulation of RNA biosynthetic process
0.38	GO:1900078	positive regulation of cellular response to insulin stimulus
0.38	GO:0032355	response to estradiol
0.38	GO:0045670	regulation of osteoclast differentiation

0.75	GO:0003707	steroid hormone receptor activity
0.66	GO:0005496	steroid binding
0.65	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.45	GO:0019904	protein domain specific binding
0.44	GO:0001012	RNA polymerase II regulatory region DNA binding
0.42	GO:0003690	double-stranded DNA binding
0.32	GO:0016491	oxidoreductase activity
0.32	GO:0003723	RNA binding

0.61	GO:0005634	nucleus
0.48	GO:0045171	intercellular bridge
0.43	GO:0015630	microtubule cytoskeleton
0.42	GO:0043233	organelle lumen
0.39	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.32

GO:0016491

tr|T1FX75|T1FX75_HELRO
Uncharacterized protein
Search

NME5

0.40	Nucleoside diphosphate kinase

0.79	GO:0006228	UTP biosynthetic process
0.79	GO:0006183	GTP biosynthetic process
0.75	GO:0046036	CTP metabolic process
0.70	GO:0006165	nucleoside diphosphate phosphorylation
0.57	GO:0048515	spermatid differentiation
0.53	GO:1902176	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
0.50	GO:0003351	epithelial cilium movement
0.50	GO:0021591	ventricular system development
0.47	GO:0007281	germ cell development
0.47	GO:0060271	cilium assembly

0.79	GO:0004550	nucleoside diphosphate kinase activity
0.45	GO:0032559	adenyl ribonucleotide binding
0.44	GO:0008144	drug binding
0.44	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0046872	metal ion binding
0.35	GO:0004430	1-phosphatidylinositol 4-kinase activity
0.32	GO:0004519	endonuclease activity

0.49	GO:0036126	sperm flagellum
0.40	GO:0005737	cytoplasm
0.32	GO:0005856	cytoskeleton
0.32	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016020	membrane

0.79	EC:2.7.4.6	GO:0004550
0.35	KEGG:R03361	GO:0004430

tr|T1FX76|T1FX76_HELRO
Uncharacterized protein
Search

0.63	GO:0007155	cell adhesion
0.58	GO:0007202	activation of phospholipase C activity
0.57	GO:0045123	cellular extravasation
0.57	GO:0002092	positive regulation of receptor internalization
0.55	GO:0070555	response to interleukin-1
0.50	GO:0030029	actin filament-based process
0.49	GO:1905226	regulation of adhesion of symbiont to host epithelial cell
0.48	GO:0043152	induction of bacterial agglutination
0.48	GO:0052405	negative regulation by host of symbiont molecular function
0.48	GO:0043129	surfactant homeostasis

0.58	GO:0033691	sialic acid binding
0.58	GO:0030246	carbohydrate binding
0.58	GO:0043274	phospholipase binding
0.49	GO:0004888	transmembrane signaling receptor activity
0.48	GO:0005509	calcium ion binding
0.38	GO:0042802	identical protein binding
0.35	GO:0005044	scavenger receptor activity
0.35	GO:0001530	lipopolysaccharide binding
0.35	GO:0001871	pattern binding
0.34	GO:0005507	copper ion binding

0.55	GO:0005901	caveola
0.53	GO:0005905	clathrin-coated pit
0.53	GO:0030863	cortical cytoskeleton
0.52	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0005581	collagen trimer
0.50	GO:0005615	extracellular space
0.47	GO:0005887	integral component of plasma membrane
0.36	GO:0005578	proteinaceous extracellular matrix
0.35	GO:0005771	multivesicular body
0.35	GO:0005791	rough endoplasmic reticulum

tr|T1FX77|T1FX77_HELRO
Uncharacterized protein
Search

tr|T1FX78|T1FX78_HELRO
Uncharacterized protein
Search

0.48	MAP/microtubule affinity-regulating kinase 4

0.77	GO:0030010	establishment of cell polarity
0.72	GO:0000226	microtubule cytoskeleton organization
0.63	GO:0006468	protein phosphorylation
0.44	GO:0007399	nervous system development
0.37	GO:0008284	positive regulation of cell proliferation
0.37	GO:0035556	intracellular signal transduction
0.36	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity
0.35	GO:0031346	positive regulation of cell projection organization
0.35	GO:0010769	regulation of cell morphogenesis involved in differentiation
0.35	GO:0010720	positive regulation of cell development

0.69	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0050321	tau-protein kinase activity
0.46	GO:0043015	gamma-tubulin binding
0.44	GO:0008017	microtubule binding
0.35	GO:0045296	cadherin binding
0.34	GO:0060072	large conductance calcium-activated potassium channel activity
0.34	GO:0000287	magnesium ion binding

0.46	GO:0036064	ciliary basal body
0.45	GO:0005813	centrosome
0.44	GO:0043005	neuron projection
0.37	GO:0000930	gamma-tubulin complex
0.37	GO:0099513	polymeric cytoskeletal fiber
0.36	GO:0005634	nucleus
0.36	GO:0097427	microtubule bundle
0.36	GO:0016328	lateral plasma membrane
0.35	GO:0045180	basal cortex
0.35	GO:0015629	actin cytoskeleton

0.69

GO:0004674

tr|T1FX79|T1FX79_HELRO
Aminoacylase
Search

ACY1

0.65	LOW QUALITY PROTEIN: aminoacylase-1

0.60	GO:0006520	cellular amino acid metabolic process
0.57	GO:0006508	proteolysis
0.33	GO:0006886	intracellular protein transport
0.33	GO:0008033	tRNA processing
0.33	GO:0032259	methylation

0.85	GO:0004046	aminoacylase activity
0.63	GO:0008237	metallopeptidase activity
0.34	GO:0008536	Ran GTPase binding
0.33	GO:0008270	zinc ion binding
0.33	GO:0008168	methyltransferase activity
0.32	GO:0003676	nucleic acid binding

0.49	GO:0005737	cytoplasm
0.33	GO:0005634	nucleus

0.85

EC:3.5.1.14

GO:0004046

tr|T1FX80|T1FX80_HELRO
Uncharacterized protein
Search

0.10	B-cell CLL/lymphoma 7 protein family member C

0.48

GO:0045892

negative regulation of transcription, DNA-templated

0.44

GO:0005515

protein binding

0.30

GO:0044425

membrane part

tr|T1FX81|T1FX81_HELRO
Uncharacterized protein
Search

0.46	Phytanoyl-CoA dioxygenase

0.52	GO:0055114	oxidation-reduction process
0.34	GO:0007186	G-protein coupled receptor signaling pathway

0.69	GO:0051213	dioxygenase activity
0.34	GO:0004930	G-protein coupled receptor activity

0.30

GO:0044425

membrane part

tr|T1FX82|T1FX82_HELRO
Uncharacterized protein
Search

RPS13

0.69	Ribosomal protein rps13

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.48	GO:0033119	negative regulation of RNA splicing
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0048015	phosphatidylinositol-mediated signaling
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0046854	phosphatidylinositol phosphorylation
0.34	GO:0019083	viral transcription

0.64	GO:0003735	structural constituent of ribosome
0.46	GO:0048027	mRNA 5'-UTR binding
0.44	GO:0070181	small ribosomal subunit rRNA binding
0.36	GO:1990932	5.8S rRNA binding
0.34	GO:0035091	phosphatidylinositol binding
0.33	GO:0008408	3'-5' exonuclease activity
0.33	GO:0005515	protein binding
0.33	GO:0016301	kinase activity

0.61	GO:0005840	ribosome
0.46	GO:0005730	nucleolus
0.46	GO:0044445	cytosolic part
0.36	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.33	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1FX83|T1FX83_HELRO
Uncharacterized protein
Search

tr|T1FX84|T1FX84_HELRO
Uncharacterized protein
Search

0.12	Vascular endothelial growth factor receptor 1

0.71	GO:0008543	fibroblast growth factor receptor signaling pathway
0.71	GO:0018108	peptidyl-tyrosine phosphorylation
0.68	GO:0008284	positive regulation of cell proliferation
0.47	GO:0006915	apoptotic process

0.74	GO:0005007	fibroblast growth factor-activated receptor activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.39	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1FX85|T1FX85_HELRO
Uncharacterized protein
Search

tr|T1FX86|T1FX86_HELRO
Uncharacterized protein
Search

0.76	GO:0019432	triglyceride biosynthetic process
0.71	GO:0007474	imaginal disc-derived wing vein specification
0.68	GO:0030514	negative regulation of BMP signaling pathway
0.66	GO:0019217	regulation of fatty acid metabolic process
0.66	GO:0055088	lipid homeostasis
0.63	GO:0042594	response to starvation
0.56	GO:0007029	endoplasmic reticulum organization
0.55	GO:0006997	nucleus organization
0.55	GO:0016311	dephosphorylation
0.54	GO:0009062	fatty acid catabolic process

0.67	GO:0008195	phosphatidate phosphatase activity
0.58	GO:0003713	transcription coactivator activity
0.42	GO:0044212	transcription regulatory region DNA binding
0.36	GO:0016491	oxidoreductase activity

0.75	GO:0035183	female germline ring canal inner rim
0.57	GO:0005634	nucleus
0.44	GO:0005811	lipid droplet
0.44	GO:0005737	cytoplasm
0.42	GO:0019898	extrinsic component of membrane
0.40	GO:0012505	endomembrane system
0.39	GO:0031967	organelle envelope
0.38	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

0.67

EC:3.1.3.4

GO:0008195

tr|T1FX87|T1FX87_HELRO
Uncharacterized protein
Search

0.85	Mitogen inducible protein product

0.80	GO:0007229	integrin-mediated signaling pathway
0.45	GO:0007517	muscle organ development
0.44	GO:0009887	animal organ morphogenesis
0.43	GO:0048738	cardiac muscle tissue development
0.43	GO:0007160	cell-matrix adhesion
0.42	GO:1904901	positive regulation of myosin II filament organization
0.42	GO:1903356	positive regulation of distal tip cell migration
0.42	GO:0001525	angiogenesis
0.42	GO:0040035	hermaphrodite genitalia development
0.42	GO:0060279	positive regulation of ovulation

0.40	GO:0043621	protein self-association
0.40	GO:0005178	integrin binding
0.39	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.36	GO:0005198	structural molecule activity

0.45	GO:0030054	cell junction
0.42	GO:0005856	cytoskeleton
0.41	GO:0055120	striated muscle dense body
0.41	GO:0031430	M band
0.38	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.37	GO:0005654	nucleoplasm
0.36	GO:0031258	lamellipodium membrane
0.35	GO:0031674	I band
0.35	GO:0043234	protein complex
0.34	GO:0005938	cell cortex

tr|T1FX88|T1FX88_HELRO
Uncharacterized protein
Search

tr|T1FX89|T1FX89_HELRO
Uncharacterized protein
Search

0.61	programmed cell death 6-interacting protein-like

0.74	GO:0000281	mitotic cytokinesis
0.73	GO:0048133	male germ-line stem cell asymmetric division
0.73	GO:1990182	exosomal secretion
0.73	GO:0048132	female germ-line stem cell asymmetric division
0.68	GO:0046330	positive regulation of JNK cascade
0.67	GO:0030041	actin filament polymerization
0.62	GO:1903553	positive regulation of extracellular exosome assembly
0.62	GO:0090611	ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway
0.61	GO:1903543	positive regulation of exosomal secretion
0.59	GO:0000920	cell separation after cytokinesis

0.63	GO:0031871	proteinase activated receptor binding
0.59	GO:0048306	calcium-dependent protein binding
0.53	GO:0042803	protein homodimerization activity
0.46	GO:0005112	Notch binding
0.45	GO:0008022	protein C-terminus binding
0.41	GO:0017124	SH3 domain binding
0.40	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.40	GO:0046982	protein heterodimerization activity
0.36	GO:0003676	nucleic acid binding
0.35	GO:0046872	metal ion binding

0.75	GO:0030496	midbody
0.68	GO:0045171	intercellular bridge
0.68	GO:0070938	contractile ring
0.64	GO:0005815	microtubule organizing center
0.59	GO:0070971	endoplasmic reticulum exit site
0.59	GO:0001772	immunological synapse
0.56	GO:0070062	extracellular exosome
0.56	GO:0042641	actomyosin
0.54	GO:0043209	myelin sheath
0.50	GO:0005829	cytosol

tr|T1FX90|T1FX90_HELRO
Uncharacterized protein
Search

0.11	Zinc finger MYM-type protein 1

0.34	GO:0016310	phosphorylation
0.34	GO:0006357	regulation of transcription by RNA polymerase II
0.34	GO:0007275	multicellular organism development

0.68	GO:0046983	protein dimerization activity
0.35	GO:0016301	kinase activity
0.34	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.33	GO:0003677	DNA binding

0.34	GO:0005654	nucleoplasm
0.32	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

tr|T1FX91|T1FX91_HELRO
Uncharacterized protein
Search

MTRF1L

0.42	Mitochondrial translational release factor 1 like

0.74	GO:0006415	translational termination
0.34	GO:0032543	mitochondrial translation

0.75

GO:0003747

translation release factor activity

0.42	GO:0005739	mitochondrion
0.33	GO:0070013	intracellular organelle lumen
0.32	GO:0044446	intracellular organelle part

tr|T1FX92|T1FX92_HELRO
Uncharacterized protein
Search

tr|T1FX93|T1FX93_HELRO
Uncharacterized protein
Search

tr|T1FX94|T1FX94_HELRO
Uncharacterized protein
Search

0.64	Voltage and ligand gated potassium channel

0.72	GO:0071805	potassium ion transmembrane transport
0.67	GO:0034765	regulation of ion transmembrane transport
0.65	GO:0023014	signal transduction by protein phosphorylation
0.62	GO:0000160	phosphorelay signal transduction system
0.39	GO:0042391	regulation of membrane potential
0.37	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.36	GO:0019098	reproductive behavior
0.35	GO:0048150	behavioral response to ether
0.35	GO:0042066	perineurial glial growth
0.34	GO:0003008	system process

0.76	GO:0005249	voltage-gated potassium channel activity
0.66	GO:0000155	phosphorelay sensor kinase activity
0.34	GO:0019901	protein kinase binding

0.44	GO:0005622	intracellular
0.37	GO:0005887	integral component of plasma membrane
0.36	GO:0009986	cell surface
0.34	GO:0031528	microvillus membrane
0.34	GO:0034705	potassium channel complex

0.66

EC:2.7.3

GO:0000155

tr|T1FX95|T1FX95_HELRO
Uncharacterized protein
Search

tr|T1FX96|T1FX96_HELRO
Uncharacterized protein
Search

PKNOX1

0.96	Homeobox-containing protein PKNOX1

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0030218	erythrocyte differentiation
0.53	GO:0030217	T cell differentiation
0.52	GO:0051254	positive regulation of RNA metabolic process
0.52	GO:0010557	positive regulation of macromolecule biosynthetic process
0.52	GO:0031328	positive regulation of cellular biosynthetic process
0.52	GO:0006366	transcription by RNA polymerase II
0.52	GO:0001525	angiogenesis

0.55	GO:0003677	DNA binding
0.54	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.53	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.49	GO:0046982	protein heterodimerization activity
0.41	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.41	GO:0003682	chromatin binding
0.33	GO:0005432	calcium:sodium antiporter activity

0.61	GO:0005634	nucleus
0.49	GO:0005667	transcription factor complex
0.39	GO:0005737	cytoplasm
0.33	GO:0043233	organelle lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

tr|T1FX97|T1FX97_HELRO
Uncharacterized protein
Search

0.12	General transcription factor ii-i repeat domain-containing protein 2-like protein (Fragment)

0.68

GO:0046983

protein dimerization activity

0.30

GO:0044425

membrane part

tr|T1FX98|T1FX98_HELRO
Uncharacterized protein
Search

0.88	Putative mitochondrial ribosomal protein l12 strongylocentrotus purpuratus

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.45	GO:0016049	cell growth
0.43	GO:0007005	mitochondrion organization
0.43	GO:0006839	mitochondrial transport
0.42	GO:0000959	mitochondrial RNA metabolic process
0.40	GO:0045893	positive regulation of transcription, DNA-templated
0.36	GO:0034654	nucleobase-containing compound biosynthetic process

0.64	GO:0003735	structural constituent of ribosome
0.43	GO:0003682	chromatin binding
0.36	GO:0022857	transmembrane transporter activity
0.35	GO:0004967	glucagon receptor activity
0.33	GO:0016301	kinase activity
0.33	GO:0046872	metal ion binding
0.32	GO:0003677	DNA binding

0.61	GO:0005840	ribosome
0.45	GO:0005759	mitochondrial matrix
0.39	GO:0031966	mitochondrial membrane
0.38	GO:0019866	organelle inner membrane
0.33	GO:0005634	nucleus
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1FX99|T1FX99_HELRO
Rhomboid-like protein
Search

0.61	GO:0006508	proteolysis
0.52	GO:0050709	negative regulation of protein secretion
0.49	GO:0042058	regulation of epidermal growth factor receptor signaling pathway
0.43	GO:0051604	protein maturation
0.39	GO:0061136	regulation of proteasomal protein catabolic process
0.39	GO:0008283	cell proliferation
0.38	GO:0016477	cell migration
0.35	GO:0015031	protein transport
0.34	GO:0015671	oxygen transport

0.69	GO:0004252	serine-type endopeptidase activity
0.37	GO:0019838	growth factor binding
0.34	GO:0005344	oxygen carrier activity
0.34	GO:0019825	oxygen binding
0.33	GO:0020037	heme binding
0.33	GO:0005506	iron ion binding

0.48	GO:0005789	endoplasmic reticulum membrane
0.40	GO:0005886	plasma membrane
0.38	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0004252

tr|T1FXA0|T1FXA0_HELRO
Uncharacterized protein
Search

0.63	Neuronal PAS domain protein 3 isoform H

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.42	GO:0007425	epithelial cell fate determination, open tracheal system
0.41	GO:1902680	positive regulation of RNA biosynthetic process
0.41	GO:0035277	spiracle morphogenesis, open tracheal system
0.41	GO:0007443	Malpighian tubule morphogenesis
0.40	GO:0007435	salivary gland morphogenesis
0.40	GO:0072175	epithelial tube formation

0.68	GO:0046983	protein dimerization activity
0.47	GO:0003677	DNA binding
0.41	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.41	GO:0005829	cytosol
0.41	GO:0043233	organelle lumen
0.38	GO:0044446	intracellular organelle part

tr|T1FXA1|T1FXA1_HELRO
Elongation of very long chain fatty acids protein
Search

ELOVL7

0.55	Elongation of very long chain fatty acids protein 5

0.76	GO:0019367	fatty acid elongation, saturated fatty acid
0.75	GO:0042761	very long-chain fatty acid biosynthetic process
0.67	GO:0019368	fatty acid elongation, unsaturated fatty acid
0.65	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process
0.62	GO:0006636	unsaturated fatty acid biosynthetic process
0.48	GO:0030148	sphingolipid biosynthetic process
0.35	GO:0045723	positive regulation of fatty acid biosynthetic process
0.33	GO:0090378	seed trichome elongation

0.82	GO:0102756	very-long-chain 3-ketoacyl-CoA synthase activity
0.82	GO:0102338	3-oxo-lignoceronyl-CoA synthase activity
0.82	GO:0102336	3-oxo-arachidoyl-CoA synthase activity
0.82	GO:0102337	3-oxo-cerotoyl-CoA synthase activity
0.76	GO:0009922	fatty acid elongase activity
0.33	GO:0005515	protein binding

0.62	GO:0005783	endoplasmic reticulum
0.57	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.54	GO:0031984	organelle subcompartment
0.41	GO:0030425	dendrite
0.34	GO:0043025	neuronal cell body
0.30	GO:0031224	intrinsic component of membrane

0.82

EC:2.3.1.199

GO:0102338

tr|T1FXA2|T1FXA2_HELRO
Uncharacterized protein
Search

0.53	GO:0035335	peptidyl-tyrosine dephosphorylation
0.48	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity
0.39	GO:0046488	phosphatidylinositol metabolic process
0.39	GO:0035023	regulation of Rho protein signal transduction
0.39	GO:0030258	lipid modification
0.37	GO:0048015	phosphatidylinositol-mediated signaling
0.37	GO:0002949	tRNA threonylcarbamoyladenosine modification
0.36	GO:0016310	phosphorylation
0.34	GO:0006897	endocytosis
0.34	GO:0006886	intracellular protein transport

0.54	GO:0046872	metal ion binding
0.53	GO:0004725	protein tyrosine phosphatase activity
0.46	GO:0032266	phosphatidylinositol-3-phosphate binding
0.39	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.37	GO:0061711	N(6)-L-threonylcarbamoyladenine synthase
0.36	GO:0034597	phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity
0.36	GO:0016301	kinase activity
0.35	GO:0030276	clathrin binding
0.35	GO:0003779	actin binding
0.34	GO:0016773	phosphotransferase activity, alcohol group as acceptor

0.47	GO:0031901	early endosome membrane
0.42	GO:0005829	cytosol
0.39	GO:0000408	EKC/KEOPS complex
0.35	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.53

GO:0004725

tr|T1FXA3|T1FXA3_HELRO
Uncharacterized protein
Search

0.85	Putative 4-mercaptohistidine N1-methyltransferase

0.63

GO:0032259

methylation

0.63

GO:0008168

methyltransferase activity

0.63

GO:0008168

tr|T1FXA4|T1FXA4_HELRO
Uncharacterized protein
Search

0.67	Dopamine receptor, invertebrate (Fragment)

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.40	GO:0007615	anesthesia-resistant memory
0.36	GO:0019933	cAMP-mediated signaling
0.36	GO:0018108	peptidyl-tyrosine phosphorylation
0.35	GO:0007267	cell-cell signaling
0.33	GO:0007166	cell surface receptor signaling pathway

0.72	GO:0004930	G-protein coupled receptor activity
0.57	GO:0030594	neurotransmitter receptor activity
0.42	GO:0001653	peptide receptor activity
0.36	GO:0004715	non-membrane spanning protein tyrosine kinase activity

0.50	GO:0005887	integral component of plasma membrane
0.32	GO:0005622	intracellular

0.36

GO:0004715

tr|T1FXA5|T1FXA5_HELRO
Uncharacterized protein
Search

ISPD

0.67	Isoprenoid synthase domain containing

0.71	GO:0008299	isoprenoid biosynthetic process
0.62	GO:0035269	protein O-linked mannosylation
0.58	GO:0007411	axon guidance
0.37	GO:0060049	regulation of protein glycosylation
0.37	GO:0048854	brain morphogenesis
0.37	GO:0048747	muscle fiber development

0.76	GO:0070567	cytidylyltransferase activity
0.55	GO:0042803	protein homodimerization activity

0.51

GO:0005829

cytosol

tr|T1FXA6|T1FXA6_HELRO
Uncharacterized protein
Search

tr|T1FXA7|T1FXA7_HELRO
Uncharacterized protein
Search

0.10	Putative chitin synthase/hyaluronan synthase glycosyltransferase (Fragment)

0.40	GO:0006038	cell wall chitin biosynthetic process
0.39	GO:0006035	cuticle chitin biosynthetic process
0.35	GO:0061063	positive regulation of nematode larval development
0.33	GO:0007018	microtubule-based movement
0.33	GO:0055085	transmembrane transport

0.69	GO:0016758	transferase activity, transferring hexosyl groups
0.39	GO:0008194	UDP-glycosyltransferase activity
0.34	GO:0003779	actin binding
0.33	GO:0003777	microtubule motor activity
0.33	GO:0008017	microtubule binding
0.33	GO:0005215	transporter activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.39	GO:0030428	cell septum
0.35	GO:0071944	cell periphery
0.34	GO:0016459	myosin complex
0.30	GO:0016020	membrane

0.69

GO:0016758

tr|T1FXA8|T1FXA8_HELRO
Uncharacterized protein
Search

0.60	Polyadenylate-binding protein II

0.49	GO:1904247	positive regulation of polynucleotide adenylyltransferase activity
0.33	GO:0006397	mRNA processing
0.33	GO:0006520	cellular amino acid metabolic process
0.32	GO:0055114	oxidation-reduction process

0.59	GO:0003723	RNA binding
0.36	GO:0043621	protein self-association
0.34	GO:0016639	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor

0.39	GO:0016607	nuclear speck
0.35	GO:0005774	vacuolar membrane
0.34	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:1.4.1

GO:0016639

tr|T1FXA9|T1FXA9_HELRO
Uncharacterized protein
Search

CLASP2

0.95	Cytoplasmic linker associated protein 2 (Fragment)

0.40	GO:1903690	negative regulation of wound healing, spreading of epidermal cells
0.40	GO:1904259	regulation of basement membrane assembly involved in embryonic body morphogenesis
0.40	GO:0090091	positive regulation of extracellular matrix disassembly
0.40	GO:1901203	positive regulation of extracellular matrix assembly
0.40	GO:0030953	astral microtubule organization
0.40	GO:0051497	negative regulation of stress fiber assembly
0.39	GO:0010458	exit from mitosis
0.39	GO:0007026	negative regulation of microtubule depolymerization
0.39	GO:0040019	positive regulation of embryonic development
0.39	GO:0010470	regulation of gastrulation

0.85	GO:0043515	kinetochore binding
0.85	GO:0051010	microtubule plus-end binding
0.39	GO:0002162	dystroglycan binding

0.85	GO:0005828	kinetochore microtubule
0.83	GO:0005881	cytoplasmic microtubule
0.40	GO:0031592	centrosomal corona
0.40	GO:0045180	basal cortex
0.40	GO:0030981	cortical microtubule cytoskeleton
0.40	GO:0005794	Golgi apparatus
0.38	GO:0005925	focal adhesion
0.38	GO:0000776	kinetochore
0.36	GO:0005829	cytosol

tr|T1FXB0|T1FXB0_HELRO
Uncharacterized protein
Search

PFKM

0.43	ATP-dependent 6-phosphofructokinase

0.79	GO:0006002	fructose 6-phosphate metabolic process
0.78	GO:0061615	glycolytic process through fructose-6-phosphate
0.49	GO:0061718	glucose catabolic process to pyruvate
0.49	GO:0006735	NADH regeneration
0.48	GO:0050796	regulation of insulin secretion
0.48	GO:0046716	muscle cell cellular homeostasis
0.47	GO:0090277	positive regulation of peptide hormone secretion
0.47	GO:0050714	positive regulation of protein secretion
0.46	GO:0042593	glucose homeostasis
0.46	GO:0005980	glycogen catabolic process

0.79	GO:0003872	6-phosphofructokinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0070061	fructose binding
0.51	GO:0046872	metal ion binding
0.47	GO:0008022	protein C-terminus binding
0.47	GO:0019900	kinase binding
0.45	GO:0042802	identical protein binding
0.42	GO:0046983	protein dimerization activity

0.51	GO:0005945	6-phosphofructokinase complex
0.48	GO:0097228	sperm principal piece
0.46	GO:0016324	apical plasma membrane
0.40	GO:0005634	nucleus
0.37	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.79

EC:2.7.1.11

GO:0003872

tr|T1FXB1|T1FXB1_HELRO
Uncharacterized protein
Search

0.61	GO:0006508	proteolysis
0.36	GO:0006869	lipid transport
0.32	GO:0008610	lipid biosynthetic process
0.32	GO:0055114	oxidation-reduction process

0.78	GO:0004181	metallocarboxypeptidase activity
0.63	GO:0008270	zinc ion binding
0.36	GO:0005319	lipid transporter activity
0.32	GO:0005506	iron ion binding
0.32	GO:0016491	oxidoreductase activity

0.38	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

0.78

GO:0004181

tr|T1FXB2|T1FXB2_HELRO
Uncharacterized protein
Search

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.43	GO:0048731	system development
0.42	GO:0007163	establishment or maintenance of cell polarity
0.42	GO:0048468	cell development
0.41	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.41	GO:0120036	plasma membrane bounded cell projection organization
0.41	GO:0035329	hippo signaling
0.40	GO:0060429	epithelium development
0.40	GO:0035239	tube morphogenesis
0.40	GO:0072137	condensed mesenchymal cell proliferation

0.70	GO:0005509	calcium ion binding
0.37	GO:0050839	cell adhesion molecule binding
0.35	GO:0004888	transmembrane signaling receptor activity
0.34	GO:0008013	beta-catenin binding
0.33	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity
0.33	GO:0045295	gamma-catenin binding
0.33	GO:0032794	GTPase activating protein binding
0.33	GO:0030506	ankyrin binding
0.33	GO:0004022	alcohol dehydrogenase (NAD) activity
0.33	GO:0004713	protein tyrosine kinase activity

0.56	GO:0005886	plasma membrane
0.43	GO:0098858	actin-based cell projection
0.42	GO:0005911	cell-cell junction
0.42	GO:0048471	perinuclear region of cytoplasm
0.41	GO:0030027	lamellipodium
0.40	GO:0045177	apical part of cell
0.38	GO:0043005	neuron projection
0.38	GO:0032421	stereocilium bundle
0.37	GO:0005634	nucleus
0.37	GO:0005912	adherens junction

0.33

EC:2.7.11.23

GO:0008353

tr|T1FXB3|T1FXB3_HELRO
Uncharacterized protein
Search

AGBL4

0.50	Cytosolic carboxypeptidase

0.59	GO:0006508	proteolysis
0.48	GO:0035609	C-terminal protein deglutamylation
0.47	GO:0035610	protein side chain deglutamylation
0.43	GO:0051607	defense response to virus
0.35	GO:0018991	oviposition
0.33	GO:0006360	transcription by RNA polymerase I

0.75	GO:0004181	metallocarboxypeptidase activity
0.61	GO:0008270	zinc ion binding
0.42	GO:0015631	tubulin binding
0.33	GO:0001054	RNA polymerase I activity
0.32	GO:0003677	DNA binding

0.46	GO:0036064	ciliary basal body
0.46	GO:0005814	centriole
0.42	GO:0005794	Golgi apparatus
0.41	GO:0005829	cytosol
0.33	GO:0005736	DNA-directed RNA polymerase I complex
0.30	GO:0016020	membrane

0.75

GO:0004181

tr|T1FXB4|T1FXB4_HELRO
Peptidyl-prolyl cis-trans isomerase
Search

PPIC

0.41	Peptidyl-prolyl cis-trans isomerase C

0.72	GO:0000413	protein peptidyl-prolyl isomerization
0.66	GO:0006457	protein folding
0.39	GO:0045087	innate immune response
0.39	GO:0002252	immune effector process
0.39	GO:0006914	autophagy
0.39	GO:0009615	response to virus
0.39	GO:0098542	defense response to other organism
0.38	GO:0045069	regulation of viral genome replication
0.38	GO:0016567	protein ubiquitination
0.36	GO:0034389	lipid particle organization

0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.43	GO:0016018	cyclosporin A binding
0.38	GO:0004842	ubiquitin-protein transferase activity
0.37	GO:0043022	ribosome binding
0.37	GO:0051082	unfolded protein binding
0.36	GO:0008270	zinc ion binding
0.35	GO:0003723	RNA binding
0.34	GO:0043565	sequence-specific DNA binding
0.33	GO:0046790	virion binding
0.32	GO:0042802	identical protein binding

0.36	GO:0005829	cytosol
0.36	GO:0005576	extracellular region
0.36	GO:0005634	nucleus
0.34	GO:0043209	myelin sheath
0.34	GO:0031982	vesicle
0.33	GO:0005925	focal adhesion
0.33	GO:0005788	endoplasmic reticulum lumen
0.33	GO:0030496	midbody
0.32	GO:0031514	motile cilium
0.32	GO:0005773	vacuole

0.72	EC:5.2.1.8	GO:0003755
0.38	KEGG:R03876	GO:0004842

tr|T1FXB5|T1FXB5_HELRO
Uncharacterized protein
Search

MTR

0.52	Methionine synthase

0.71	GO:0009086	methionine biosynthetic process
0.69	GO:0042558	pteridine-containing compound metabolic process
0.62	GO:0032259	methylation
0.48	GO:0009235	cobalamin metabolic process
0.38	GO:0071732	cellular response to nitric oxide
0.38	GO:0031103	axon regeneration
0.36	GO:0061431	cellular response to methionine
0.34	GO:0050667	homocysteine metabolic process
0.34	GO:0006305	DNA alkylation
0.34	GO:0044728	DNA methylation or demethylation

0.79	GO:0008705	methionine synthase activity
0.74	GO:0031419	cobalamin binding
0.62	GO:0008270	zinc ion binding
0.35	GO:0005542	folic acid binding
0.34	GO:0016597	amino acid binding
0.33	GO:0005515	protein binding

0.49	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.79	EC:2.1.1.13	GO:0008705
0.79	KEGG:R00946	GO:0008705

tr|T1FXB6|T1FXB6_HELRO
Uncharacterized protein
Search

0.50	GO:0007507	heart development
0.50	GO:0001568	blood vessel development
0.43	GO:0003250	regulation of cell proliferation involved in heart valve morphogenesis
0.42	GO:0048570	notochord morphogenesis
0.42	GO:0006030	chitin metabolic process
0.41	GO:0001885	endothelial cell development
0.40	GO:0007155	cell adhesion
0.39	GO:0090287	regulation of cellular response to growth factor stimulus
0.38	GO:0071363	cellular response to growth factor stimulus
0.38	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway

0.70	GO:0005509	calcium ion binding
0.56	GO:0005201	extracellular matrix structural constituent
0.53	GO:0050436	microfibril binding
0.51	GO:0050431	transforming growth factor beta binding
0.42	GO:0008061	chitin binding
0.38	GO:0016504	peptidase activator activity
0.36	GO:0004888	transmembrane signaling receptor activity
0.35	GO:0005178	integrin binding
0.35	GO:0008201	heparin binding
0.34	GO:0042802	identical protein binding

0.58	GO:0005578	proteinaceous extracellular matrix
0.52	GO:0001527	microfibril
0.46	GO:0005615	extracellular space
0.40	GO:0043234	protein complex
0.35	GO:0043025	neuronal cell body
0.35	GO:0030425	dendrite
0.35	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0005788	endoplasmic reticulum lumen
0.33	GO:0005739	mitochondrion
0.32	GO:0005634	nucleus

0.33

GO:0004725

tr|T1FXB7|T1FXB7_HELRO
DNA-directed RNA polymerase subunit beta
Search

0.41	DNA-directed RNA polymerase subunit beta

0.58	GO:0006351	transcription, DNA-templated
0.46	GO:0045793	positive regulation of cell size
0.44	GO:0016049	cell growth
0.35	GO:0016072	rRNA metabolic process

0.70	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.65	GO:0001882	nucleoside binding
0.54	GO:0003677	DNA binding
0.33	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.40	GO:0000428	DNA-directed RNA polymerase complex
0.38	GO:0031974	membrane-enclosed lumen
0.36	GO:0043232	intracellular non-membrane-bounded organelle
0.36	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.70

GO:0003899

tr|T1FXB8|T1FXB8_HELRO
Uncharacterized protein
Search

0.71	RNA binding protein Bruno-like 5a

0.42	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.41	GO:0032224	positive regulation of synaptic transmission, cholinergic
0.41	GO:0032230	positive regulation of synaptic transmission, GABAergic
0.40	GO:0007271	synaptic transmission, cholinergic
0.39	GO:0045664	regulation of neuron differentiation
0.36	GO:0030575	nuclear body organization
0.36	GO:0048026	positive regulation of mRNA splicing, via spliceosome
0.36	GO:0030317	flagellated sperm motility
0.36	GO:0098781	ncRNA transcription
0.35	GO:0007283	spermatogenesis

0.59	GO:0003723	RNA binding
0.33	GO:0008270	zinc ion binding
0.32	GO:0050660	flavin adenine dinucleotide binding
0.32	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors

0.40	GO:0016604	nuclear body
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.32

EC:1.1

GO:0016614

tr|T1FXB9|T1FXB9_HELRO
Uncharacterized protein
Search

0.42	ATP-dependent 6-phosphofructokinase

0.79	GO:0006002	fructose 6-phosphate metabolic process
0.78	GO:0061615	glycolytic process through fructose-6-phosphate
0.44	GO:0046835	carbohydrate phosphorylation
0.35	GO:1990830	cellular response to leukemia inhibitory factor

0.79	GO:0003872	6-phosphofructokinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0046872	metal ion binding
0.37	GO:0047334	diphosphate-fructose-6-phosphate 1-phosphotransferase activity
0.35	GO:0045296	cadherin binding
0.34	GO:0032403	protein complex binding

0.48	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.79

EC:2.7.1.11

GO:0003872

tr|T1FXC0|T1FXC0_HELRO
Uncharacterized protein
Search

TRHR

0.89	Thyrotropin-releasing hormone receptor a

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.34	GO:0090073	positive regulation of protein homodimerization activity
0.34	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.33	GO:0018108	peptidyl-tyrosine phosphorylation

0.86	GO:0004997	thyrotropin-releasing hormone receptor activity
0.33	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.33	GO:0042803	protein homodimerization activity
0.33	GO:0016520	growth hormone-releasing hormone receptor activity
0.32	GO:0004983	neuropeptide Y receptor activity

0.34	GO:0005886	plasma membrane
0.33	GO:0009986	cell surface
0.30	GO:0016021	integral component of membrane

0.33

GO:0004715

tr|T1FXC1|T1FXC1_HELRO
Uncharacterized protein
Search

tr|T1FXC2|T1FXC2_HELRO
Uncharacterized protein
Search

DCAF13

0.82	WD repeat and SOF domain-containing protein 1

0.64	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.46	GO:0070647	protein modification by small protein conjugation or removal
0.38	GO:0043687	post-translational protein modification
0.38	GO:0016573	histone acetylation
0.37	GO:0070897	DNA-templated transcriptional preinitiation complex assembly
0.37	GO:0006511	ubiquitin-dependent protein catabolic process
0.36	GO:0045454	cell redox homeostasis
0.36	GO:0007186	G-protein coupled receptor signaling pathway
0.35	GO:0006413	translational initiation
0.34	GO:0006355	regulation of transcription, DNA-templated

0.47	GO:0030331	estrogen receptor binding
0.39	GO:0003723	RNA binding
0.38	GO:0004402	histone acetyltransferase activity
0.37	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.37	GO:0017025	TBP-class protein binding
0.36	GO:0004930	G-protein coupled receptor activity
0.34	GO:0003677	DNA binding
0.33	GO:0046872	metal ion binding

0.71	GO:0005730	nucleolus
0.69	GO:0005813	centrosome
0.68	GO:0080008	Cul4-RING E3 ubiquitin ligase complex
0.67	GO:0030054	cell junction
0.63	GO:0032040	small-subunit processome
0.62	GO:0005829	cytosol
0.37	GO:0072686	mitotic spindle
0.36	GO:0005654	nucleoplasm
0.30	GO:0016021	integral component of membrane

0.38

GO:0004402

tr|T1FXC3|T1FXC3_HELRO
Uncharacterized protein
Search

0.10	FEZ family zinc finger 2 (Fragment)

0.53	GO:0021797	forebrain anterior/posterior pattern specification
0.52	GO:0043697	cell dedifferentiation
0.50	GO:0021772	olfactory bulb development
0.50	GO:0001764	neuron migration
0.49	GO:0007411	axon guidance
0.49	GO:0045666	positive regulation of neuron differentiation
0.48	GO:0008285	negative regulation of cell proliferation
0.47	GO:0000122	negative regulation of transcription by RNA polymerase II
0.46	GO:0045893	positive regulation of transcription, DNA-templated
0.38	GO:0021879	forebrain neuron differentiation

0.51	GO:0003676	nucleic acid binding
0.49	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.47	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.36	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.36	GO:0046872	metal ion binding
0.35	GO:0003682	chromatin binding
0.33	GO:0008080	N-acetyltransferase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0016491	oxidoreductase activity
0.32	GO:0032555	purine ribonucleotide binding

0.43	GO:0005829	cytosol
0.43	GO:0005634	nucleus
0.33	GO:0043233	organelle lumen
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.32	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0008080

tr|T1FXC4|T1FXC4_HELRO
Uncharacterized protein
Search

PUS7

0.89	Pseudouridylate synthase 7

0.72	GO:0001522	pseudouridine synthesis
0.38	GO:0040031	snRNA modification
0.37	GO:0006396	RNA processing
0.37	GO:0016556	mRNA modification
0.36	GO:0006399	tRNA metabolic process
0.36	GO:0022613	ribonucleoprotein complex biogenesis
0.35	GO:0016072	rRNA metabolic process
0.35	GO:0048193	Golgi vesicle transport
0.34	GO:0050684	regulation of mRNA processing
0.34	GO:0071826	ribonucleoprotein complex subunit organization

0.72	GO:0009982	pseudouridine synthase activity
0.59	GO:0003723	RNA binding
0.49	GO:0019899	enzyme binding
0.37	GO:0004730	pseudouridylate synthase activity
0.34	GO:0004674	protein serine/threonine kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.42	GO:0005634	nucleus
0.34	GO:0005783	endoplasmic reticulum
0.33	GO:0005615	extracellular space
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.72	EC:5.4.99.12	GO:0009982
0.37	KEGG:R01055	GO:0004730

tr|T1FXC5|T1FXC5_HELRO
Uncharacterized protein
Search

OVOL1

0.66	Ovo like transcriptional repressor 1

0.52	GO:0051729	germline cell cycle switching, mitotic to meiotic cell cycle
0.51	GO:0008544	epidermis development
0.50	GO:1901994	negative regulation of meiotic cell cycle phase transition
0.50	GO:2000647	negative regulation of stem cell proliferation
0.49	GO:0000122	negative regulation of transcription by RNA polymerase II
0.48	GO:0007498	mesoderm development
0.48	GO:0043588	skin development
0.48	GO:0001822	kidney development
0.47	GO:0007283	spermatogenesis
0.44	GO:0070896	positive regulation of transposon integration

0.51	GO:0003676	nucleic acid binding
0.49	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.34	GO:0046872	metal ion binding

0.43	GO:0005634	nucleus
0.33	GO:0043233	organelle lumen
0.32	GO:0044446	intracellular organelle part
0.32	GO:0005737	cytoplasm

tr|T1FXC6|T1FXC6_HELRO
Golgi SNAP receptor complex member 1
Search

GOSR1

0.72	Golgi SNAP receptor complex member 1

0.76	GO:0006888	ER to Golgi vesicle-mediated transport
0.58	GO:0015031	protein transport
0.49	GO:0048209	regulation of vesicle targeting, to, from or within Golgi
0.49	GO:0042147	retrograde transport, endosome to Golgi
0.47	GO:0061025	membrane fusion
0.47	GO:0006891	intra-Golgi vesicle-mediated transport
0.46	GO:0048284	organelle fusion
0.46	GO:0016050	vesicle organization

0.53	GO:0005484	SNAP receptor activity
0.47	GO:0000149	SNARE binding

0.80	GO:0005801	cis-Golgi network
0.72	GO:0000139	Golgi membrane
0.48	GO:0005797	Golgi medial cisterna
0.47	GO:0031201	SNARE complex
0.44	GO:0005829	cytosol
0.35	GO:0000138	Golgi trans cisterna
0.34	GO:0030133	transport vesicle
0.30	GO:0016021	integral component of membrane

tr|T1FXC7|T1FXC7_HELRO
Uncharacterized protein
Search

CNEP1R1

0.76	Nuclear envelope phosphatase-regulatory subunit 1

0.85	GO:0035307	positive regulation of protein dephosphorylation
0.54	GO:0010867	positive regulation of triglyceride biosynthetic process
0.48	GO:0034504	protein localization to nucleus
0.37	GO:0006629	lipid metabolic process
0.35	GO:0007077	mitotic nuclear envelope disassembly

0.33

GO:0005515

protein binding

0.86	GO:0071595	Nem1-Spo7 phosphatase complex
0.49	GO:0031965	nuclear membrane
0.45	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|T1FXC8|T1FXC8_HELRO
Uncharacterized protein
Search

0.28	Monocarboxylate transporter 5

0.55	GO:0055085	transmembrane transport
0.46	GO:0015718	monocarboxylic acid transport
0.39	GO:0006629	lipid metabolic process
0.38	GO:0070327	thyroid hormone transport
0.37	GO:0015850	organic hydroxy compound transport
0.36	GO:0007281	germ cell development
0.33	GO:0035234	ectopic germ cell programmed cell death

0.46	GO:0008028	monocarboxylic acid transmembrane transporter activity
0.38	GO:0015349	thyroid hormone transmembrane transporter activity
0.37	GO:1901618	organic hydroxy compound transmembrane transporter activity
0.34	GO:0015293	symporter activity
0.32	GO:0005515	protein binding

0.41	GO:0005789	endoplasmic reticulum membrane
0.41	GO:0005887	integral component of plasma membrane
0.33	GO:0005794	Golgi apparatus

tr|T1FXC9|T1FXC9_HELRO
Palmitoyltransferase
Search

0.54	Palmitoyltransferase

0.44	GO:0018345	protein palmitoylation
0.35	GO:0016188	synaptic vesicle maturation
0.32	GO:0055114	oxidation-reduction process

0.79	GO:0019706	protein-cysteine S-palmitoyltransferase activity
0.32	GO:0016491	oxidoreductase activity
0.31	GO:0003676	nucleic acid binding

0.37	GO:0005886	plasma membrane
0.33	GO:0042765	GPI-anchor transamidase complex

0.79

GO:0019706

tr|T1FXD0|T1FXD0_HELRO
Uncharacterized protein
Search

0.10	E3 ubiquitin-protein ligase PDZRN3

0.56	GO:0016567	protein ubiquitination
0.42	GO:0070201	regulation of establishment of protein localization
0.34	GO:0046598	positive regulation of viral entry into host cell
0.34	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.34	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling

0.57	GO:0004842	ubiquitin-protein transferase activity
0.54	GO:0008270	zinc ion binding
0.44	GO:0016874	ligase activity
0.34	GO:0042802	identical protein binding
0.34	GO:0003723	RNA binding

0.45	GO:0016235	aggresome
0.37	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.44	EC:6	GO:0016874
0.57	KEGG:R03876	GO:0004842

tr|T1FXD1|T1FXD1_HELRO
Uncharacterized protein
Search

0.85	Quaking protein A

0.67	GO:0006417	regulation of translation
0.36	GO:1903311	regulation of mRNA metabolic process
0.36	GO:0001709	cell fate determination
0.35	GO:0043484	regulation of RNA splicing
0.35	GO:0007438	oenocyte development
0.35	GO:0007284	spermatogonial cell division
0.35	GO:2000026	regulation of multicellular organismal development
0.35	GO:0007475	apposition of dorsal and ventral imaginal disc-derived wing surfaces
0.35	GO:0008078	mesodermal cell migration
0.35	GO:0042693	muscle cell fate commitment

0.74	GO:0003727	single-stranded RNA binding
0.38	GO:0046872	metal ion binding
0.35	GO:0003730	mRNA 3'-UTR binding
0.35	GO:0097157	pre-mRNA intronic binding
0.34	GO:0048027	mRNA 5'-UTR binding
0.33	GO:0005515	protein binding

0.36	GO:0043186	P granule
0.33	GO:0005634	nucleus
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

tr|T1FXD2|T1FXD2_HELRO
Uncharacterized protein
Search

SLC35B2

0.84	Adenosine 3'-phospho 5'-phosphosulfate transporter

0.55	GO:0055085	transmembrane transport
0.49	GO:0046963	3'-phosphoadenosine 5'-phosphosulfate transport
0.40	GO:0006518	peptide metabolic process
0.40	GO:0043604	amide biosynthetic process
0.39	GO:1901566	organonitrogen compound biosynthetic process
0.39	GO:0019538	protein metabolic process
0.39	GO:0031290	retinal ganglion cell axon guidance
0.38	GO:0009059	macromolecule biosynthetic process
0.38	GO:0042476	odontogenesis
0.38	GO:0001649	osteoblast differentiation

0.49	GO:0046964	3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity
0.42	GO:0003735	structural constituent of ribosome
0.34	GO:0005242	inward rectifier potassium channel activity
0.33	GO:0070003	threonine-type peptidase activity
0.33	GO:0016746	transferase activity, transferring acyl groups
0.33	GO:0004175	endopeptidase activity

0.44	GO:0030173	integral component of Golgi membrane
0.42	GO:0030176	integral component of endoplasmic reticulum membrane
0.41	GO:0005840	ribosome
0.33	GO:0019773	proteasome core complex, alpha-subunit complex
0.32	GO:0005634	nucleus

0.33

EC:2.3

GO:0016746

tr|T1FXD3|T1FXD3_HELRO
Uncharacterized protein
Search

0.51	DNA-directed RNA polymerase I

0.58	GO:0006351	transcription, DNA-templated
0.33	GO:0006413	translational initiation

0.70	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.63	GO:0008270	zinc ion binding
0.55	GO:0003677	DNA binding
0.38	GO:0051087	chaperone binding
0.33	GO:0003743	translation initiation factor activity

0.44	GO:0005736	DNA-directed RNA polymerase I complex
0.43	GO:0005666	DNA-directed RNA polymerase III complex
0.43	GO:0005665	DNA-directed RNA polymerase II, core complex
0.30	GO:0031224	intrinsic component of membrane

0.70

GO:0003899

tr|T1FXD4|T1FXD4_HELRO
Katanin p60 ATPase-containing subunit A-like 2
Search

KATNAL2

0.92	Katanin p60 ATPase containing subunit

0.78

GO:0051013

microtubule severing

0.79	GO:0008568	microtubule-severing ATPase activity
0.69	GO:0008017	microtubule binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0032553	ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding

0.74	GO:0000922	spindle pole
0.68	GO:0005874	microtubule
0.47	GO:0005737	cytoplasm
0.41	GO:0005634	nucleus

0.79

EC:3.6.4.3

GO:0008568

tr|T1FXD5|T1FXD5_HELRO
Uncharacterized protein
Search

FZD7

0.94	Frizzled class receptor 1

0.77	GO:0016055	Wnt signaling pathway
0.68	GO:0007275	multicellular organism development
0.55	GO:0035412	regulation of catenin import into nucleus
0.54	GO:0060429	epithelium development
0.54	GO:0042666	negative regulation of ectodermal cell fate specification
0.53	GO:0014834	skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration
0.52	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing
0.52	GO:2000726	negative regulation of cardiac muscle cell differentiation
0.51	GO:0009653	anatomical structure morphogenesis
0.51	GO:0048103	somatic stem cell division

0.84	GO:0042813	Wnt-activated receptor activity
0.58	GO:0017147	Wnt-protein binding
0.55	GO:0005109	frizzled binding
0.54	GO:0030165	PDZ domain binding
0.50	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.45	GO:0004930	G-protein coupled receptor activity
0.37	GO:0045545	syndecan binding
0.34	GO:0042803	protein homodimerization activity
0.34	GO:0046982	protein heterodimerization activity
0.33	GO:0004672	protein kinase activity

0.50	GO:0055038	recycling endosome membrane
0.41	GO:0005886	plasma membrane
0.41	GO:0009986	cell surface
0.36	GO:0005925	focal adhesion
0.35	GO:1990909	Wnt signalosome
0.34	GO:0043005	neuron projection
0.30	GO:0016021	integral component of membrane

tr|T1FXD6|T1FXD6_HELRO
Uncharacterized protein
Search

0.77	Methylmalonic aciduria and homocystinuria type D, mitochondrial

0.72	GO:0009235	cobalamin metabolic process
0.43	GO:0009108	coenzyme biosynthetic process

0.33

GO:0005515

protein binding

0.42	GO:0005739	mitochondrion
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|T1FXD7|T1FXD7_HELRO
Uncharacterized protein
Search

0.61	Pikachurin

0.63	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.37	GO:0007389	pattern specification process
0.37	GO:0000904	cell morphogenesis involved in differentiation
0.37	GO:0030182	neuron differentiation
0.37	GO:0120036	plasma membrane bounded cell projection organization
0.37	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.37	GO:0007422	peripheral nervous system development
0.36	GO:0007417	central nervous system development
0.36	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.35	GO:0044331	cell-cell adhesion mediated by cadherin

0.70	GO:0005509	calcium ion binding
0.35	GO:0050839	cell adhesion molecule binding
0.34	GO:0008013	beta-catenin binding
0.33	GO:0070492	oligosaccharide binding
0.33	GO:0002020	protease binding
0.33	GO:0042803	protein homodimerization activity
0.32	GO:0004872	receptor activity
0.32	GO:0016887	ATPase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding

0.47	GO:0005886	plasma membrane
0.33	GO:0030425	dendrite
0.33	GO:0030424	axon
0.33	GO:0005911	cell-cell junction
0.33	GO:0009986	cell surface
0.33	GO:0098552	side of membrane
0.31	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

0.32

GO:0016887

tr|T1FXD8|T1FXD8_HELRO
Uncharacterized protein
Search

PDPK1

0.57	3-phosphoinositide-dependent protein kinase 1

0.63	GO:0006468	protein phosphorylation
0.54	GO:1905564	positive regulation of vascular endothelial cell proliferation
0.53	GO:0032148	activation of protein kinase B activity
0.53	GO:0071364	cellular response to epidermal growth factor stimulus
0.53	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol
0.53	GO:0010518	positive regulation of phospholipase activity
0.52	GO:0043536	positive regulation of blood vessel endothelial cell migration
0.52	GO:1903078	positive regulation of protein localization to plasma membrane
0.52	GO:0007173	epidermal growth factor receptor signaling pathway
0.52	GO:0097191	extrinsic apoptotic signaling pathway

0.64	GO:0004672	protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0016004	phospholipase activator activity
0.54	GO:0043274	phospholipase binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0032555	purine ribonucleotide binding
0.38	GO:0005158	insulin receptor binding
0.37	GO:0019901	protein kinase binding

0.48	GO:0014069	postsynaptic density
0.45	GO:0042995	cell projection
0.44	GO:0031410	cytoplasmic vesicle
0.40	GO:0005886	plasma membrane
0.38	GO:0043204	perikaryon
0.37	GO:0005925	focal adhesion
0.35	GO:0005829	cytosol
0.34	GO:0005634	nucleus
0.33	GO:0070013	intracellular organelle lumen
0.32	GO:0044446	intracellular organelle part

tr|T1FXD9|T1FXD9_HELRO
Uncharacterized protein
Search

CLCN2

0.43	Chloride channel, voltage-sensitive 1b

0.77	GO:1902476	chloride transmembrane transport
0.35	GO:0060689	cell differentiation involved in salivary gland development
0.35	GO:0060041	retina development in camera-type eye
0.32	GO:0034765	regulation of ion transmembrane transport

0.78

GO:0005247

voltage-gated chloride channel activity

0.33	GO:0034707	chloride channel complex
0.31	GO:0005886	plasma membrane

tr|T1FXE0|T1FXE0_HELRO
Uncharacterized protein
Search

0.77	GO:0035725	sodium ion transmembrane transport
0.76	GO:0034765	regulation of ion transmembrane transport
0.48	GO:0019233	sensory perception of pain
0.36	GO:0001508	action potential
0.36	GO:0035637	multicellular organismal signaling
0.35	GO:0045433	male courtship behavior, veined wing generated song production
0.35	GO:0060371	regulation of atrial cardiac muscle cell membrane depolarization
0.35	GO:0007638	mechanosensory behavior
0.34	GO:0051899	membrane depolarization
0.34	GO:0055117	regulation of cardiac muscle contraction

0.84	GO:0005248	voltage-gated sodium channel activity
0.73	GO:0022832	voltage-gated channel activity
0.71	GO:0022839	ion gated channel activity
0.70	GO:0008381	mechanosensitive ion channel activity
0.66	GO:0005509	calcium ion binding
0.34	GO:0044325	ion channel binding

0.83

GO:0001518

voltage-gated sodium channel complex

tr|T1FXE2|T1FXE2_HELRO
Uncharacterized protein
Search

0.35	Promiscuous glyoxal/methylglyoxal reductase

0.53	GO:0055114	oxidation-reduction process
0.37	GO:0006396	RNA processing

0.54	GO:0016491	oxidoreductase activity
0.39	GO:0004000	adenosine deaminase activity
0.36	GO:0003723	RNA binding

0.30

GO:0031224

intrinsic component of membrane

0.54

GO:0016491

tr|T1FXE3|T1FXE3_HELRO
Uncharacterized protein
Search

0.48	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.46	GO:0016567	protein ubiquitination
0.38	GO:0032463	negative regulation of protein homooligomerization
0.38	GO:0090073	positive regulation of protein homodimerization activity
0.38	GO:0034766	negative regulation of ion transmembrane transport
0.34	GO:0035118	embryonic pectoral fin morphogenesis
0.34	GO:0071600	otic vesicle morphogenesis
0.34	GO:0060173	limb development

0.53	GO:0046872	metal ion binding
0.36	GO:0008233	peptidase activity
0.33	GO:0005515	protein binding

0.51	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex
0.46	GO:0005730	nucleolus
0.37	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.36