Queries 17001 to 18000

GO:0004252

tr|T1FRP8|T1FRP8_HELRO
Uncharacterized protein
Search

0.48	GO:0000256	allantoin catabolic process
0.41	GO:0006402	mRNA catabolic process
0.40	GO:0036211	protein modification process
0.39	GO:0044267	cellular protein metabolic process
0.38	GO:0016310	phosphorylation
0.37	GO:2001141	regulation of RNA biosynthetic process
0.37	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:0043085	positive regulation of catalytic activity
0.36	GO:0031285	regulation of sorocarp stalk cell differentiation
0.36	GO:0043327	chemotaxis to cAMP

0.49	GO:0004037	allantoicase activity
0.43	GO:0008270	zinc ion binding
0.43	GO:0003676	nucleic acid binding
0.39	GO:0140096	catalytic activity, acting on a protein
0.39	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.39	GO:0016301	kinase activity
0.39	GO:0017076	purine nucleotide binding
0.39	GO:0032553	ribonucleotide binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0003700	DNA binding transcription factor activity

0.41	GO:0030014	CCR4-NOT complex
0.35	GO:0005634	nucleus
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.49	EC:3.5.3.4	GO:0004037
0.49	KEGG:R02422	GO:0004037

tr|T1FRP9|T1FRP9_HELRO
Uncharacterized protein
Search

0.80	GO:0050808	synapse organization
0.42	GO:0007268	chemical synaptic transmission
0.41	GO:0099643	signal release from synapse
0.40	GO:0006836	neurotransmitter transport
0.39	GO:0051649	establishment of localization in cell
0.39	GO:0001505	regulation of neurotransmitter levels
0.38	GO:1903744	positive regulation of anterograde synaptic vesicle transport
0.38	GO:1905608	positive regulation of presynapse assembly
0.37	GO:2000582	positive regulation of ATP-dependent microtubule motor activity, plus-end-directed
0.37	GO:0018991	oviposition

0.37	GO:0030159	receptor signaling complex scaffold activity
0.37	GO:0019894	kinesin binding
0.35	GO:0042803	protein homodimerization activity
0.33	GO:0016491	oxidoreductase activity

0.75	GO:0045202	synapse
0.41	GO:0097458	neuron part
0.35	GO:0120025	plasma membrane bounded cell projection
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.33

GO:0016491

tr|T1FRQ0|T1FRQ0_HELRO
Uncharacterized protein
Search

0.51	GO:0070417	cellular response to cold
0.49	GO:0000027	ribosomal large subunit assembly
0.47	GO:0006401	RNA catabolic process

0.54	GO:0004386	helicase activity
0.52	GO:0003723	RNA binding
0.49	GO:0008186	RNA-dependent ATPase activity
0.46	GO:0032559	adenyl ribonucleotide binding
0.46	GO:0008144	drug binding
0.46	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0140098	catalytic activity, acting on RNA

0.47	GO:0019013	viral nucleocapsid
0.43	GO:0030529	intracellular ribonucleoprotein complex
0.38	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|T1FRQ1|T1FRQ1_HELRO
Uncharacterized protein
Search

0.30

GO:0044425

membrane part

tr|T1FRQ2|T1FRQ2_HELRO
Uncharacterized protein
Search

tr|T1FRQ3|T1FRQ3_HELRO
Uncharacterized protein
Search

0.71	GO:0034198	cellular response to amino acid starvation
0.70	GO:0032007	negative regulation of TOR signaling
0.69	GO:0035909	aorta morphogenesis
0.67	GO:0003281	ventricular septum development
0.67	GO:0060021	palate development
0.66	GO:0048738	cardiac muscle tissue development
0.61	GO:0043547	positive regulation of GTPase activity
0.59	GO:0038202	TORC1 signaling
0.58	GO:2000785	regulation of autophagosome assembly
0.39	GO:0045493	xylan catabolic process

0.62	GO:0005096	GTPase activator activity
0.40	GO:0030248	cellulose binding
0.40	GO:0031176	endo-1,4-beta-xylanase activity
0.38	GO:0003729	mRNA binding
0.38	GO:0004402	histone acetyltransferase activity
0.37	GO:0004672	protein kinase activity
0.37	GO:0030554	adenyl nucleotide binding
0.37	GO:0004012	phospholipid-translocating ATPase activity
0.37	GO:0032555	purine ribonucleotide binding
0.37	GO:0008144	drug binding

0.73	GO:1990130	GATOR1 complex
0.65	GO:0005765	lysosomal membrane
0.40	GO:0044451	nucleoplasm part
0.38	GO:0031248	protein acetyltransferase complex
0.37	GO:0005881	cytoplasmic microtubule
0.37	GO:0005576	extracellular region
0.36	GO:0005815	microtubule organizing center
0.34	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.40

EC:3.2.1.8

GO:0031176

tr|T1FRQ4|T1FRQ4_HELRO
Uncharacterized protein
Search

0.61	GO:0006508	proteolysis
0.48	GO:0048240	sperm capacitation
0.48	GO:0007340	acrosome reaction
0.48	GO:0007339	binding of sperm to zona pellucida
0.47	GO:0051604	protein maturation
0.42	GO:0032902	nerve growth factor production
0.42	GO:0042445	hormone metabolic process
0.41	GO:0007354	zygotic determination of anterior/posterior axis, embryo
0.41	GO:1905910	negative regulation of dauer entry
0.41	GO:0007368	determination of left/right symmetry

0.69	GO:0004252	serine-type endopeptidase activity
0.41	GO:0048406	nerve growth factor binding
0.40	GO:0008201	heparin binding
0.37	GO:0005102	receptor binding
0.36	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.34	GO:0008376	acetylgalactosaminyltransferase activity
0.34	GO:0042277	peptide binding
0.33	GO:0008942	nitrite reductase [NAD(P)H] activity
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.48	GO:0002080	acrosomal membrane
0.39	GO:0005615	extracellular space
0.38	GO:0009986	cell surface
0.38	GO:0043025	neuronal cell body
0.38	GO:0031012	extracellular matrix
0.36	GO:0005794	Golgi apparatus
0.35	GO:0005783	endoplasmic reticulum
0.34	GO:0030424	axon
0.34	GO:0043233	organelle lumen
0.34	GO:0031984	organelle subcompartment

0.69	EC:3.4.21	GO:0004252
0.33	KEGG:R00787 KEGG:R00789	GO:0008942

tr|T1FRQ5|T1FRQ5_HELRO
Uncharacterized protein
Search

0.64	GO:0006260	DNA replication
0.43	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.43	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity
0.39	GO:0051321	meiotic cell cycle
0.37	GO:0051301	cell division

0.42	GO:0019901	protein kinase binding
0.37	GO:0003723	RNA binding

0.61	GO:0005634	nucleus
0.37	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part

tr|T1FRQ6|T1FRQ6_HELRO
Uncharacterized protein
Search

0.47	GO:0006396	RNA processing
0.42	GO:0006468	protein phosphorylation
0.42	GO:0065009	regulation of molecular function
0.40	GO:0031154	culmination involved in sorocarp development
0.39	GO:0097696	STAT cascade
0.39	GO:0009966	regulation of signal transduction
0.39	GO:0007275	multicellular organism development
0.38	GO:0030435	sporulation resulting in formation of a cellular spore
0.38	GO:0006996	organelle organization
0.38	GO:0097435	supramolecular fiber organization

0.44	GO:0004674	protein serine/threonine kinase activity
0.43	GO:0098772	molecular function regulator
0.40	GO:0032559	adenyl ribonucleotide binding
0.40	GO:0043168	anion binding
0.40	GO:0008144	drug binding
0.40	GO:0005102	receptor binding
0.38	GO:0046872	metal ion binding
0.38	GO:0004386	helicase activity
0.38	GO:0042302	structural constituent of cuticle
0.38	GO:0043565	sequence-specific DNA binding

0.41	GO:0005634	nucleus
0.39	GO:0044446	intracellular organelle part
0.39	GO:0061645	endocytic patch
0.39	GO:0030863	cortical cytoskeleton
0.38	GO:0031974	membrane-enclosed lumen
0.38	GO:0015629	actin cytoskeleton
0.36	GO:0005694	chromosome
0.35	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

0.44	EC:2.7.11	GO:0004674
0.37	KEGG:R06847	GO:0004764

tr|T1FRQ7|T1FRQ7_HELRO
Uncharacterized protein
Search

0.58	GO:0046854	phosphatidylinositol phosphorylation
0.54	GO:0035556	intracellular signal transduction
0.38	GO:0006458	'de novo' protein folding
0.38	GO:0042147	retrograde transport, endosome to Golgi
0.38	GO:0061077	chaperone-mediated protein folding
0.36	GO:0030261	chromosome condensation
0.35	GO:0006353	DNA-templated transcription, termination
0.35	GO:0006914	autophagy
0.35	GO:0044780	bacterial-type flagellum assembly
0.34	GO:0015031	protein transport

0.62	GO:0016307	phosphatidylinositol phosphate kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0046872	metal ion binding
0.41	GO:0032266	phosphatidylinositol-3-phosphate binding
0.39	GO:0044183	protein binding involved in protein folding
0.37	GO:0051082	unfolded protein binding
0.36	GO:0008186	RNA-dependent ATPase activity
0.35	GO:0004386	helicase activity

0.42	GO:0000329	fungal-type vacuole membrane
0.41	GO:0070772	PAS complex
0.41	GO:0010008	endosome membrane
0.36	GO:0005829	cytosol
0.35	GO:0009424	bacterial-type flagellum hook
0.30	GO:0016021	integral component of membrane

0.62

GO:0016307

tr|T1FRQ8|T1FRQ8_HELRO
Uncharacterized protein
Search

0.51	GO:0031047	gene silencing by RNA
0.46	GO:0009435	NAD biosynthetic process
0.42	GO:0000278	mitotic cell cycle
0.42	GO:0045893	positive regulation of transcription, DNA-templated
0.41	GO:0030154	cell differentiation
0.41	GO:0006357	regulation of transcription by RNA polymerase II
0.38	GO:0007165	signal transduction
0.38	GO:0006351	transcription, DNA-templated

0.48	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity
0.45	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting
0.45	GO:0003676	nucleic acid binding
0.44	GO:0005549	odorant binding
0.43	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.42	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.40	GO:0008270	zinc ion binding
0.37	GO:0030554	adenyl nucleotide binding
0.36	GO:0032555	purine ribonucleotide binding
0.36	GO:0008144	drug binding

0.42	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.48	EC:2.4.2.19	GO:0004514
0.48	KEGG:R03348	GO:0004514

tr|T1FRQ9|T1FRQ9_HELRO
Uncharacterized protein
Search

tr|T1FRR0|T1FRR0_HELRO
Uncharacterized protein
Search

0.74	GO:0034453	microtubule anchoring
0.39	GO:0048015	phosphatidylinositol-mediated signaling
0.38	GO:0046854	phosphatidylinositol phosphorylation
0.36	GO:0016311	dephosphorylation
0.35	GO:0000027	ribosomal large subunit assembly
0.35	GO:0016567	protein ubiquitination
0.35	GO:0006396	RNA processing
0.34	GO:0016072	rRNA metabolic process
0.34	GO:0051103	DNA ligation involved in DNA repair
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.52	GO:0005509	calcium ion binding
0.38	GO:0004430	1-phosphatidylinositol 4-kinase activity
0.37	GO:0016887	ATPase activity
0.37	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0016791	phosphatase activity
0.35	GO:0008092	cytoskeletal protein binding
0.35	GO:0004842	ubiquitin-protein transferase activity
0.35	GO:0016874	ligase activity

0.67	GO:0005815	microtubule organizing center
0.36	GO:0030687	preribosome, large subunit precursor
0.30	GO:0016020	membrane

0.38	EC:2.7.1.67	GO:0004430
0.38	KEGG:R03361	GO:0004430

tr|T1FRR1|T1FRR1_HELRO
Uncharacterized protein
Search

0.63	GO:0048015	phosphatidylinositol-mediated signaling
0.60	GO:0046854	phosphatidylinositol phosphorylation
0.45	GO:0006904	vesicle docking involved in exocytosis
0.43	GO:2001141	regulation of RNA biosynthetic process
0.43	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.43	GO:0010468	regulation of gene expression
0.42	GO:0008608	attachment of spindle microtubules to kinetochore
0.41	GO:0051983	regulation of chromosome segregation
0.41	GO:0000070	mitotic sister chromatid segregation
0.38	GO:0071173	spindle assembly checkpoint

0.50	GO:0016301	kinase activity
0.45	GO:0003700	DNA binding transcription factor activity
0.40	GO:0003677	DNA binding
0.39	GO:0008270	zinc ion binding
0.39	GO:0046982	protein heterodimerization activity
0.38	GO:0043130	ubiquitin binding
0.38	GO:0004815	aspartate-tRNA ligase activity
0.37	GO:0003924	GTPase activity
0.36	GO:0032550	purine ribonucleoside binding
0.36	GO:0032561	guanyl ribonucleotide binding

0.41	GO:0005622	intracellular
0.40	GO:1990298	bub1-bub3 complex
0.39	GO:0043227	membrane-bounded organelle
0.38	GO:0044422	organelle part
0.37	GO:0043228	non-membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

0.38

EC:6.1.1.12

GO:0004815

tr|T1FRR2|T1FRR2_HELRO
Uncharacterized protein
Search

tr|T1FRR3|T1FRR3_HELRO
Uncharacterized protein
Search

0.75	GO:0051965	positive regulation of synapse assembly
0.52	GO:0046426	negative regulation of JAK-STAT cascade
0.50	GO:0006469	negative regulation of protein kinase activity
0.49	GO:0019221	cytokine-mediated signaling pathway
0.38	GO:0035023	regulation of Rho protein signal transduction
0.36	GO:0006742	NADP catabolic process
0.35	GO:0007286	spermatid development
0.35	GO:0019363	pyridine nucleotide biosynthetic process
0.34	GO:0007155	cell adhesion
0.34	GO:0051806	entry into cell of other organism involved in symbiotic interaction

0.51	GO:0004860	protein kinase inhibitor activity
0.50	GO:0005102	receptor binding
0.40	GO:0005509	calcium ion binding
0.38	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.36	GO:0004386	helicase activity
0.35	GO:0050839	cell adhesion molecule binding
0.35	GO:1901265	nucleoside phosphate binding
0.35	GO:0042803	protein homodimerization activity
0.35	GO:0046982	protein heterodimerization activity
0.34	GO:0036094	small molecule binding

0.58	GO:0044300	cerebellar mossy fiber
0.40	GO:0042734	presynaptic membrane
0.40	GO:0030054	cell junction
0.38	GO:0005737	cytoplasm
0.35	GO:0005604	basement membrane
0.35	GO:0016604	nuclear body
0.30	GO:0016021	integral component of membrane

0.33

GO:0016491

tr|T1FRR4|T1FRR4_HELRO
Uncharacterized protein
Search

tr|T1FRR5|T1FRR5_HELRO
Uncharacterized protein
Search

0.40	GO:0007043	cell-cell junction assembly
0.39	GO:0048731	system development
0.39	GO:0005975	carbohydrate metabolic process
0.38	GO:0036211	protein modification process
0.37	GO:0006508	proteolysis
0.37	GO:0006955	immune response
0.37	GO:0044267	cellular protein metabolic process
0.37	GO:0016311	dephosphorylation
0.37	GO:0006898	receptor-mediated endocytosis
0.37	GO:0009057	macromolecule catabolic process

0.43	GO:0001871	pattern binding
0.40	GO:0030246	carbohydrate binding
0.40	GO:0140096	catalytic activity, acting on a protein
0.39	GO:0016787	hydrolase activity
0.39	GO:0005044	scavenger receptor activity
0.37	GO:0005509	calcium ion binding
0.37	GO:0008417	fucosyltransferase activity
0.36	GO:0017056	structural constituent of nuclear pore
0.35	GO:0008270	zinc ion binding
0.34	GO:0003677	DNA binding

0.44	GO:0005576	extracellular region
0.37	GO:0032580	Golgi cisterna membrane
0.30	GO:0031224	intrinsic component of membrane

0.39

GO:0016787

tr|T1FRR6|T1FRR6_HELRO
Uncharacterized protein
Search

0.45	GO:0006298	mismatch repair
0.44	GO:0036211	protein modification process
0.42	GO:0016032	viral process
0.42	GO:0006325	chromatin organization
0.42	GO:0044267	cellular protein metabolic process
0.40	GO:0043414	macromolecule methylation
0.39	GO:0044248	cellular catabolic process
0.39	GO:0006796	phosphate-containing compound metabolic process
0.39	GO:0007154	cell communication
0.39	GO:0016180	snRNA processing

0.45	GO:0030983	mismatched DNA binding
0.44	GO:0140096	catalytic activity, acting on a protein
0.42	GO:0016278	lysine N-methyltransferase activity
0.42	GO:0030554	adenyl nucleotide binding
0.42	GO:0097367	carbohydrate derivative binding
0.42	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0008144	drug binding
0.40	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.40	GO:0005057	signal transducer activity, downstream of receptor
0.40	GO:0016301	kinase activity

0.47	GO:0032300	mismatch repair complex
0.42	GO:0005634	nucleus
0.41	GO:0036338	viral membrane
0.40	GO:0005694	chromosome
0.39	GO:0000428	DNA-directed RNA polymerase complex
0.39	GO:0070013	intracellular organelle lumen
0.37	GO:0070578	RISC-loading complex
0.37	GO:0044446	intracellular organelle part
0.37	GO:0035068	micro-ribonucleoprotein complex
0.37	GO:0016442	RISC complex

0.42

GO:0016278

tr|T1FRR7|T1FRR7_HELRO
Uncharacterized protein
Search

tr|T1FRR8|T1FRR8_HELRO
Uncharacterized protein
Search

0.40	GO:0042744	hydrogen peroxide catabolic process
0.40	GO:0016043	cellular component organization
0.40	GO:0005975	carbohydrate metabolic process
0.39	GO:0007163	establishment or maintenance of cell polarity
0.39	GO:0006950	response to stress
0.39	GO:0006468	protein phosphorylation
0.39	GO:0071852	fungal-type cell wall organization or biogenesis
0.39	GO:0007155	cell adhesion
0.38	GO:0098869	cellular oxidant detoxification
0.38	GO:1902404	mitotic actomyosin contractile ring contraction

0.42	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.41	GO:0030246	carbohydrate binding
0.41	GO:0004674	protein serine/threonine kinase activity
0.41	GO:0005518	collagen binding
0.39	GO:0004601	peroxidase activity
0.38	GO:0001871	pattern binding
0.38	GO:0003917	DNA topoisomerase type I activity
0.38	GO:0097367	carbohydrate derivative binding
0.38	GO:0008144	drug binding
0.37	GO:0050825	ice binding

0.42	GO:0005576	extracellular region
0.41	GO:0005618	cell wall
0.38	GO:0043229	intracellular organelle
0.38	GO:0031097	medial cortex
0.37	GO:0043227	membrane-bounded organelle
0.37	GO:0043332	mating projection tip
0.37	GO:0061645	endocytic patch
0.37	GO:0043228	non-membrane-bounded organelle
0.37	GO:0044422	organelle part
0.37	GO:0000131	incipient cellular bud site

0.42	EC:3.2.1	GO:0004553
0.39	KEGG:R03532	GO:0004601

tr|T1FRR9|T1FRR9_HELRO
Uncharacterized protein
Search

tr|T1FRS0|T1FRS0_HELRO
Uncharacterized protein
Search

0.46	GO:0007165	signal transduction
0.45	GO:0034220	ion transmembrane transport
0.39	GO:0032870	cellular response to hormone stimulus
0.38	GO:0006355	regulation of transcription, DNA-templated
0.37	GO:0009733	response to auxin
0.37	GO:0044260	cellular macromolecule metabolic process
0.37	GO:0090304	nucleic acid metabolic process
0.37	GO:0009059	macromolecule biosynthetic process
0.37	GO:0036211	protein modification process
0.37	GO:0043413	macromolecule glycosylation

0.52	GO:0005230	extracellular ligand-gated ion channel activity
0.50	GO:0004888	transmembrane signaling receptor activity
0.40	GO:0003677	DNA binding
0.39	GO:0046872	metal ion binding
0.38	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0140110	transcription regulator activity
0.37	GO:0031491	nucleosome binding
0.37	GO:0008157	protein phosphatase 1 binding

0.44	GO:0005634	nucleus
0.36	GO:0005874	microtubule
0.35	GO:0010008	endosome membrane
0.35	GO:0042025	host cell nucleus
0.34	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

0.36

GO:0004402

tr|T1FRS1|T1FRS1_HELRO
Uncharacterized protein
Search

tr|T1FRS2|T1FRS2_HELRO
Poly [ADP-ribose] polymerase
Search

0.26	Poly [ADP-ribose] polymerase

0.80	GO:0006471	protein ADP-ribosylation
0.48	GO:0051972	regulation of telomerase activity
0.46	GO:0006954	inflammatory response
0.46	GO:0008219	cell death
0.41	GO:0006366	transcription by RNA polymerase II
0.38	GO:0007004	telomere maintenance via telomerase
0.37	GO:0010918	positive regulation of mitochondrial membrane potential
0.36	GO:0070301	cellular response to hydrogen peroxide
0.35	GO:0006281	DNA repair
0.34	GO:0016192	vesicle-mediated transport

0.81	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.43	GO:0019899	enzyme binding
0.39	GO:0019904	protein domain specific binding
0.37	GO:0003779	actin binding
0.36	GO:0003677	DNA binding
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0003910	DNA ligase (ATP) activity

0.47	GO:0005876	spindle microtubule
0.42	GO:0005829	cytosol
0.42	GO:0005665	DNA-directed RNA polymerase II, core complex
0.36	GO:0070062	extracellular exosome
0.34	GO:0000439	core TFIIH complex
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0032807	DNA ligase IV complex
0.30	GO:0031224	intrinsic component of membrane

0.81

GO:0003950

tr|T1FRS3|T1FRS3_HELRO
Uncharacterized protein
Search

0.61	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.47	GO:0046907	intracellular transport
0.47	GO:0070727	cellular macromolecule localization
0.46	GO:0015031	protein transport
0.42	GO:0018108	peptidyl-tyrosine phosphorylation
0.41	GO:0016192	vesicle-mediated transport
0.39	GO:0048519	negative regulation of biological process
0.38	GO:0016071	mRNA metabolic process
0.38	GO:0006401	RNA catabolic process
0.38	GO:0019222	regulation of metabolic process

0.62	GO:0038062	protein tyrosine kinase collagen receptor activity
0.49	GO:0008536	Ran GTPase binding
0.39	GO:0030554	adenyl nucleotide binding
0.38	GO:0008144	drug binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0032555	purine ribonucleotide binding
0.36	GO:0004674	protein serine/threonine kinase activity
0.36	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.36	GO:0003700	DNA binding transcription factor activity
0.36	GO:0004842	ubiquitin-protein transferase activity

0.50	GO:0005887	integral component of plasma membrane
0.44	GO:0030123	AP-3 adaptor complex
0.43	GO:0005634	nucleus
0.39	GO:0030014	CCR4-NOT complex
0.37	GO:0030135	coated vesicle
0.36	GO:0020011	apicoplast
0.36	GO:0032300	mismatch repair complex
0.35	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.35	GO:0030173	integral component of Golgi membrane
0.35	GO:0070013	intracellular organelle lumen

0.36	EC:2.7.11	GO:0004674
0.36	KEGG:R03876	GO:0004842

tr|T1FRS4|T1FRS4_HELRO
Uncharacterized protein
Search

tr|T1FRS5|T1FRS5_HELRO
Uncharacterized protein
Search

0.50	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.49	GO:0007528	neuromuscular junction development
0.35	GO:0035848	oviduct morphogenesis
0.35	GO:0048621	post-embryonic digestive tract morphogenesis
0.35	GO:0030198	extracellular matrix organization
0.35	GO:0060729	intestinal epithelial structure maintenance
0.35	GO:0048468	cell development
0.35	GO:0055007	cardiac muscle cell differentiation
0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.65	GO:0005201	extracellular matrix structural constituent
0.37	GO:0030246	carbohydrate binding
0.36	GO:0005509	calcium ion binding
0.35	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.34	GO:0003677	DNA binding
0.34	GO:0005044	scavenger receptor activity
0.34	GO:0001664	G-protein coupled receptor binding
0.32	GO:0022857	transmembrane transporter activity

0.65	GO:0005604	basement membrane
0.63	GO:0005581	collagen trimer
0.51	GO:0098645	collagen network
0.49	GO:0031594	neuromuscular junction
0.35	GO:0098025	virus tail, baseplate
0.34	GO:0005788	endoplasmic reticulum lumen
0.33	GO:0019867	outer membrane
0.30	GO:0016021	integral component of membrane

0.35

GO:0004553

tr|T1FRS6|T1FRS6_HELRO
Uncharacterized protein
Search

0.53	GO:0033622	integrin activation
0.52	GO:0051894	positive regulation of focal adhesion assembly
0.52	GO:0033627	cell adhesion mediated by integrin
0.50	GO:0071230	cellular response to amino acid stimulus
0.42	GO:0035848	oviduct morphogenesis
0.41	GO:0048621	post-embryonic digestive tract morphogenesis
0.41	GO:0060729	intestinal epithelial structure maintenance
0.40	GO:0055013	cardiac muscle cell development
0.38	GO:0010951	negative regulation of endopeptidase activity
0.38	GO:0009405	pathogenesis

0.56	GO:0005201	extracellular matrix structural constituent
0.51	GO:0005178	integrin binding
0.39	GO:0005509	calcium ion binding
0.38	GO:0004867	serine-type endopeptidase inhibitor activity
0.38	GO:0030246	carbohydrate binding
0.36	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.34	GO:0017056	structural constituent of nuclear pore
0.34	GO:0003677	DNA binding
0.34	GO:0042802	identical protein binding
0.33	GO:0032559	adenyl ribonucleotide binding

0.59	GO:0005581	collagen trimer
0.54	GO:0005576	extracellular region
0.37	GO:0019867	outer membrane
0.35	GO:0005788	endoplasmic reticulum lumen
0.35	GO:0044613	nuclear pore central transport channel
0.35	GO:0099081	supramolecular polymer
0.34	GO:0005618	cell wall
0.34	GO:0005694	chromosome
0.30	GO:0016021	integral component of membrane

0.36

GO:0004553

tr|T1FRS7|T1FRS7_HELRO
Uncharacterized protein
Search

0.72	GO:0043547	positive regulation of GTPase activity
0.61	GO:0007165	signal transduction
0.58	GO:0007018	microtubule-based movement
0.35	GO:0030048	actin filament-based movement
0.34	GO:0035023	regulation of Rho protein signal transduction
0.34	GO:0006048	UDP-N-acetylglucosamine biosynthetic process
0.34	GO:0016567	protein ubiquitination

0.73	GO:0005096	GTPase activator activity
0.60	GO:0003774	motor activity
0.59	GO:0003779	actin binding
0.58	GO:0008017	microtubule binding
0.47	GO:0046872	metal ion binding
0.46	GO:0032559	adenyl ribonucleotide binding
0.46	GO:0008144	drug binding
0.46	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0008080	N-acetyltransferase activity
0.35	GO:0048495	Roundabout binding

0.61	GO:0016459	myosin complex
0.40	GO:0005737	cytoplasm
0.34	GO:0005884	actin filament
0.33	GO:0071944	cell periphery
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.38	EC:2.3.1	GO:0008080
0.34	KEGG:R03876	GO:0004842

tr|T1FRS8|T1FRS8_HELRO
Uncharacterized protein
Search

tr|T1FRS9|T1FRS9_HELRO
Uncharacterized protein
Search

0.13	Putative NICE-3 family member

0.30

GO:0044425

membrane part

tr|T1FRT0|T1FRT0_HELRO
Uncharacterized protein
Search

tr|T1FRT1|T1FRT1_HELRO
Uncharacterized protein
Search

0.44	GO:0022613	ribonucleoprotein complex biogenesis
0.41	GO:0016070	RNA metabolic process
0.41	GO:0010467	gene expression
0.40	GO:0045617	negative regulation of keratinocyte differentiation
0.40	GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis
0.39	GO:0048025	negative regulation of mRNA splicing, via spliceosome
0.39	GO:0006325	chromatin organization
0.39	GO:0010837	regulation of keratinocyte proliferation
0.39	GO:0034654	nucleobase-containing compound biosynthetic process
0.39	GO:0000381	regulation of alternative mRNA splicing, via spliceosome

0.46	GO:0003723	RNA binding
0.40	GO:0016817	hydrolase activity, acting on acid anhydrides
0.39	GO:0046872	metal ion binding
0.39	GO:0005528	FK506 binding
0.37	GO:0140096	catalytic activity, acting on a protein
0.37	GO:0016859	cis-trans isomerase activity
0.36	GO:0017076	purine nucleotide binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0032553	ribonucleotide binding
0.36	GO:0003677	DNA binding

0.48	GO:0005634	nucleus
0.45	GO:0070013	intracellular organelle lumen
0.41	GO:0044446	intracellular organelle part
0.40	GO:0043232	intracellular non-membrane-bounded organelle
0.39	GO:0030684	preribosome
0.35	GO:0043234	protein complex
0.34	GO:1990234	transferase complex
0.34	GO:0005891	voltage-gated calcium channel complex
0.34	GO:0120114	Sm-like protein family complex
0.34	GO:0048475	coated membrane

0.40

EC:3.6

GO:0016817

tr|T1FRT2|T1FRT2_HELRO
Uncharacterized protein
Search

0.44	GO:0032502	developmental process
0.43	GO:0071840	cellular component organization or biogenesis
0.43	GO:0032501	multicellular organismal process
0.42	GO:0016070	RNA metabolic process
0.42	GO:0043412	macromolecule modification
0.41	GO:0060735	regulation of eIF2 alpha phosphorylation by dsRNA
0.41	GO:0051640	organelle localization
0.41	GO:1904751	positive regulation of protein localization to nucleolus
0.40	GO:0044387	negative regulation of protein kinase activity by regulation of protein phosphorylation
0.40	GO:0032071	regulation of endodeoxyribonuclease activity

0.40	GO:0030957	Tat protein binding
0.40	GO:0003676	nucleic acid binding
0.40	GO:0140110	transcription regulator activity
0.40	GO:0043021	ribonucleoprotein complex binding
0.40	GO:0009982	pseudouridine synthase activity
0.40	GO:0051059	NF-kappaB binding
0.39	GO:0008270	zinc ion binding
0.39	GO:0140096	catalytic activity, acting on a protein
0.39	GO:0047485	protein N-terminus binding
0.39	GO:0033613	activating transcription factor binding

0.46	GO:0005730	nucleolus
0.41	GO:0030529	intracellular ribonucleoprotein complex
0.40	GO:0031616	spindle pole centrosome
0.40	GO:0043234	protein complex
0.39	GO:0005654	nucleoplasm
0.38	GO:0005578	proteinaceous extracellular matrix
0.37	GO:0009986	cell surface
0.37	GO:0048475	coated membrane
0.37	GO:0032993	protein-DNA complex
0.37	GO:0005829	cytosol

0.40

EC:5.4.99.12

GO:0009982

tr|T1FRT3|T1FRT3_HELRO
Uncharacterized protein
Search

0.65	Glutamate receptor, ionotropic, AMPA 4b

0.80	GO:0060079	excitatory postsynaptic potential
0.77	GO:0035235	ionotropic glutamate receptor signaling pathway
0.59	GO:0034220	ion transmembrane transport
0.46	GO:0048899	anterior lateral line development
0.45	GO:0048915	posterior lateral line system development
0.44	GO:0014032	neural crest cell development
0.44	GO:0048701	embryonic cranial skeleton morphogenesis
0.41	GO:0007399	nervous system development

0.82	GO:0005234	extracellularly glutamate-gated ion channel activity
0.77	GO:0004970	ionotropic glutamate receptor activity
0.42	GO:0099094	ligand-gated cation channel activity

0.78	GO:0045211	postsynaptic membrane
0.73	GO:0030054	cell junction
0.43	GO:0032281	AMPA glutamate receptor complex

tr|T1FRT4|T1FRT4_HELRO
Uncharacterized protein
Search

tr|T1FRT5|T1FRT5_HELRO
Uncharacterized protein
Search

tr|T1FRT6|T1FRT6_HELRO
Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial
Search

SUCLG2

0.86	Succinate-CoA ligase subunit beta

0.80	GO:0006104	succinyl-CoA metabolic process
0.70	GO:0006099	tricarboxylic acid cycle
0.44	GO:0048085	adult chitin-containing cuticle pigmentation
0.38	GO:0006105	succinate metabolic process

0.79	GO:0004776	succinate-CoA ligase (GDP-forming) activity
0.71	GO:0004775	succinate-CoA ligase (ADP-forming) activity
0.60	GO:0000287	magnesium ion binding
0.58	GO:0032550	purine ribonucleoside binding
0.58	GO:0019001	guanyl nucleotide binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0046982	protein heterodimerization activity
0.35	GO:0004777	succinate-semialdehyde dehydrogenase (NAD+) activity

0.54	GO:0005739	mitochondrion
0.42	GO:0042709	succinate-CoA ligase complex
0.37	GO:0005886	plasma membrane
0.37	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part

0.79	EC:6.2.1.4	GO:0004776
0.79	KEGG:R00432	GO:0004776

tr|T1FRT7|T1FRT7_HELRO
Uncharacterized protein
Search

tr|T1FRT8|T1FRT8_HELRO
Uncharacterized protein
Search

tr|T1FRT9|T1FRT9_HELRO
Uncharacterized protein
Search

tr|T1FRU0|T1FRU0_HELRO
Uncharacterized protein
Search

0.30

GO:0044425

membrane part

tr|T1FRU1|T1FRU1_HELRO
Uncharacterized protein
Search

0.71	GO:0006470	protein dephosphorylation
0.36	GO:0009788	negative regulation of abscisic acid-activated signaling pathway
0.35	GO:1902039	negative regulation of seed dormancy process
0.35	GO:0097438	exit from dormancy
0.35	GO:0009939	positive regulation of gibberellic acid mediated signaling pathway
0.35	GO:0010030	positive regulation of seed germination
0.35	GO:0010162	seed dormancy process
0.34	GO:0010118	stomatal movement
0.34	GO:0010150	leaf senescence
0.34	GO:0009658	chloroplast organization

0.76	GO:0004722	protein serine/threonine phosphatase activity
0.51	GO:0046872	metal ion binding
0.33	GO:0003700	DNA binding transcription factor activity
0.33	GO:0004672	protein kinase activity
0.33	GO:0005515	protein binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.34	GO:0033106	cis-Golgi network membrane
0.33	GO:0005794	Golgi apparatus
0.33	GO:0005829	cytosol
0.32	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

tr|T1FRU2|T1FRU2_HELRO
Uncharacterized protein
Search

TBC1D9B

0.92	TBC1 domain family member 9B isoform X4

0.46	GO:0031338	regulation of vesicle fusion
0.46	GO:0090630	activation of GTPase activity
0.41	GO:0006886	intracellular protein transport
0.33	GO:1902017	regulation of cilium assembly
0.32	GO:0055114	oxidation-reduction process

0.68	GO:0005509	calcium ion binding
0.45	GO:0017137	Rab GTPase binding
0.43	GO:0005096	GTPase activator activity
0.34	GO:0003756	protein disulfide isomerase activity
0.34	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
0.34	GO:0035091	phosphatidylinositol binding
0.33	GO:0003676	nucleic acid binding
0.31	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.41	GO:0012505	endomembrane system
0.35	GO:0005622	intracellular
0.32	GO:0043227	membrane-bounded organelle
0.30	GO:0016020	membrane

0.34

EC:5.3.4.1

GO:0003756

tr|T1FRU3|T1FRU3_HELRO
Beta-galactosidase
Search

GLB1

0.41	Beta-galactosidase

0.60	GO:0005975	carbohydrate metabolic process
0.41	GO:0051413	response to cortisone
0.40	GO:1904016	response to Thyroglobulin triiodothyronine
0.36	GO:0044282	small molecule catabolic process
0.35	GO:0042340	keratan sulfate catabolic process
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0006687	glycosphingolipid metabolic process
0.32	GO:0043044	ATP-dependent chromatin remodeling

0.76	GO:0004565	beta-galactosidase activity
0.40	GO:0016936	galactoside binding
0.34	GO:0004308	exo-alpha-sialidase activity
0.33	GO:0005515	protein binding
0.32	GO:0004386	helicase activity
0.31	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding
0.31	GO:0003677	DNA binding

0.46	GO:0005615	extracellular space
0.44	GO:0005794	Golgi apparatus
0.44	GO:0005773	vacuole
0.36	GO:1903561	extracellular vesicle
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen
0.34	GO:0048471	perinuclear region of cytoplasm
0.32	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.76

EC:3.2.1.23

GO:0004565

tr|T1FRU4|T1FRU4_HELRO
Uncharacterized protein
Search

0.58	GO:0034728	nucleosome organization
0.56	GO:0043044	ATP-dependent chromatin remodeling
0.46	GO:0060255	regulation of macromolecule metabolic process
0.45	GO:0031497	chromatin assembly
0.45	GO:0080090	regulation of primary metabolic process
0.45	GO:0031323	regulation of cellular metabolic process
0.45	GO:0051171	regulation of nitrogen compound metabolic process
0.44	GO:0009889	regulation of biosynthetic process
0.44	GO:0065004	protein-DNA complex assembly
0.41	GO:0044265	cellular macromolecule catabolic process

0.44	GO:0008270	zinc ion binding
0.42	GO:0003676	nucleic acid binding
0.41	GO:0035312	5'-3' exodeoxyribonuclease activity
0.40	GO:0004672	protein kinase activity
0.39	GO:0004107	chorismate synthase activity
0.38	GO:0032559	adenyl ribonucleotide binding
0.38	GO:0008144	drug binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.36	GO:0004867	serine-type endopeptidase inhibitor activity

0.46	GO:0005634	nucleus
0.43	GO:0000786	nucleosome
0.43	GO:0030014	CCR4-NOT complex
0.30	GO:0031224	intrinsic component of membrane

0.39	EC:4.2.3.5	GO:0004107
0.39	KEGG:R01714	GO:0004107

tr|T1FRU5|T1FRU5_HELRO
Uncharacterized protein
Search

0.43	GO:0036211	protein modification process
0.42	GO:0016310	phosphorylation
0.42	GO:0044267	cellular protein metabolic process
0.40	GO:0048015	phosphatidylinositol-mediated signaling
0.39	GO:0048102	autophagic cell death
0.38	GO:0046488	phosphatidylinositol metabolic process
0.38	GO:0030258	lipid modification
0.37	GO:0001522	pseudouridine synthesis
0.36	GO:0007018	microtubule-based movement
0.36	GO:0016569	covalent chromatin modification

0.43	GO:0140096	catalytic activity, acting on a protein
0.43	GO:0016301	kinase activity
0.43	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.41	GO:0046872	metal ion binding
0.41	GO:0097367	carbohydrate derivative binding
0.41	GO:0030554	adenyl nucleotide binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0008144	drug binding
0.40	GO:0003676	nucleic acid binding
0.37	GO:0005515	protein binding

0.40	GO:0043231	intracellular membrane-bounded organelle
0.37	GO:0044444	cytoplasmic part
0.36	GO:0012505	endomembrane system
0.36	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.35	GO:0044446	intracellular organelle part
0.35	GO:0031090	organelle membrane
0.35	GO:0031975	envelope
0.34	GO:0005694	chromosome
0.34	GO:0043233	organelle lumen
0.30	GO:0016021	integral component of membrane

0.43

GO:0016773

tr|T1FRU6|T1FRU6_HELRO
Uncharacterized protein
Search

0.76	GO:0008286	insulin receptor signaling pathway
0.51	GO:0016573	histone acetylation
0.48	GO:0007010	cytoskeleton organization
0.47	GO:0006357	regulation of transcription by RNA polymerase II
0.47	GO:0050793	regulation of developmental process
0.45	GO:0051128	regulation of cellular component organization
0.44	GO:0006468	protein phosphorylation
0.44	GO:0065008	regulation of biological quality
0.39	GO:0035072	ecdysone-mediated induction of salivary gland cell autophagic cell death
0.39	GO:0035562	negative regulation of chromatin binding

0.77	GO:0005158	insulin receptor binding
0.56	GO:0016905	myosin heavy chain kinase activity
0.51	GO:0004402	histone acetyltransferase activity
0.48	GO:0019905	syntaxin binding

0.45	GO:0005634	nucleus
0.38	GO:0030686	90S preribosome
0.38	GO:0005732	small nucleolar ribonucleoprotein complex
0.36	GO:0031974	membrane-enclosed lumen
0.35	GO:0043234	protein complex
0.35	GO:0043232	intracellular non-membrane-bounded organelle
0.34	GO:0044446	intracellular organelle part

0.56

EC:2.7.11.7

GO:0016905

tr|T1FRU7|T1FRU7_HELRO
Uncharacterized protein
Search

0.60	GO:0045977	positive regulation of mitotic cell cycle, embryonic
0.52	GO:0008219	cell death
0.51	GO:0016567	protein ubiquitination
0.45	GO:0032688	negative regulation of interferon-beta production
0.45	GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway
0.43	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.43	GO:0036503	ERAD pathway
0.42	GO:0036297	interstrand cross-link repair
0.38	GO:0007165	signal transduction
0.37	GO:0034470	ncRNA processing

0.58	GO:0070182	DNA polymerase binding
0.56	GO:0031624	ubiquitin conjugating enzyme binding
0.51	GO:0004842	ubiquitin-protein transferase activity
0.51	GO:0008270	zinc ion binding
0.47	GO:0061659	ubiquitin-like protein ligase activity
0.42	GO:0005057	signal transducer activity, downstream of receptor
0.39	GO:0016874	ligase activity
0.36	GO:0016301	kinase activity
0.36	GO:0003856	3-dehydroquinate synthase activity
0.36	GO:0003866	3-phosphoshikimate 1-carboxyvinyltransferase activity

0.46	GO:0005634	nucleus
0.44	GO:0000836	Hrd1p ubiquitin ligase complex
0.38	GO:0032040	small-subunit processome
0.37	GO:0020011	apicoplast
0.35	GO:0000428	DNA-directed RNA polymerase complex
0.35	GO:0043233	organelle lumen
0.34	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.39	EC:6	GO:0016874
0.51	KEGG:R03876	GO:0004842

tr|T1FRU8|T1FRU8_HELRO
Uncharacterized protein
Search

0.47	GO:0006325	chromatin organization
0.42	GO:0048015	phosphatidylinositol-mediated signaling
0.42	GO:0006281	DNA repair
0.41	GO:0046854	phosphatidylinositol phosphorylation
0.40	GO:0006351	transcription, DNA-templated
0.39	GO:0018205	peptidyl-lysine modification
0.38	GO:0060255	regulation of macromolecule metabolic process
0.38	GO:0033036	macromolecule localization
0.38	GO:0046907	intracellular transport
0.38	GO:0051171	regulation of nitrogen compound metabolic process

0.43	GO:0016817	hydrolase activity, acting on acid anhydrides
0.40	GO:0008536	Ran GTPase binding
0.39	GO:0046872	metal ion binding
0.38	GO:0018024	histone-lysine N-methyltransferase activity
0.38	GO:0003723	RNA binding
0.37	GO:0003700	DNA binding transcription factor activity
0.37	GO:0016772	transferase activity, transferring phosphorus-containing groups
0.37	GO:0008144	drug binding
0.37	GO:0043168	anion binding
0.37	GO:0004402	histone acetyltransferase activity

0.47	GO:0031011	Ino80 complex
0.38	GO:0005576	extracellular region
0.36	GO:0030687	preribosome, large subunit precursor
0.35	GO:0005581	collagen trimer
0.35	GO:0045025	mitochondrial degradosome
0.34	GO:0016459	myosin complex
0.34	GO:0000151	ubiquitin ligase complex
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.43

EC:3.6

GO:0016817

tr|T1FRU9|T1FRU9_HELRO
Uncharacterized protein
Search

tr|T1FRV0|T1FRV0_HELRO
Uncharacterized protein
Search

LOC108735239

0.56	Myotubularin-related protein 14

0.75	GO:0035335	peptidyl-tyrosine dephosphorylation
0.36	GO:0050881	musculoskeletal movement
0.36	GO:0046716	muscle cell cellular homeostasis
0.35	GO:0043009	chordate embryonic development
0.35	GO:0010506	regulation of autophagy
0.34	GO:0016236	macroautophagy
0.34	GO:0006661	phosphatidylinositol biosynthetic process

0.75	GO:0004725	protein tyrosine phosphatase activity
0.57	GO:0004438	phosphatidylinositol-3-phosphatase activity
0.35	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity
0.34	GO:0004722	protein serine/threonine phosphatase activity
0.33	GO:0005515	protein binding

0.53	GO:0001726	ruffle
0.51	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0005829	cytosol

0.75

GO:0004725

tr|T1FRV1|T1FRV1_HELRO
Uncharacterized protein
Search

0.39

GO:0016757

transferase activity, transferring glycosyl groups

0.30

GO:0044425

membrane part

0.39

GO:0016757

tr|T1FRV2|T1FRV2_HELRO
Uncharacterized protein
Search

tr|T1FRV3|T1FRV3_HELRO
Uncharacterized protein
Search

0.44	GO:0007165	signal transduction
0.40	GO:0032259	methylation
0.40	GO:0016042	lipid catabolic process
0.39	GO:0032446	protein modification by small protein conjugation
0.39	GO:0099120	socially cooperative development
0.39	GO:1904643	response to curcumin
0.38	GO:0018193	peptidyl-amino acid modification
0.38	GO:0060255	regulation of macromolecule metabolic process
0.38	GO:0098630	aggregation of unicellular organisms
0.38	GO:0051591	response to cAMP

0.49	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.46	GO:0016874	ligase activity
0.43	GO:0046872	metal ion binding
0.42	GO:0003723	RNA binding
0.40	GO:0008168	methyltransferase activity
0.40	GO:0019787	ubiquitin-like protein transferase activity
0.37	GO:0003700	DNA binding transcription factor activity
0.36	GO:0004672	protein kinase activity
0.36	GO:0003677	DNA binding
0.36	GO:0030553	cGMP binding

0.40	GO:0005634	nucleus
0.37	GO:0000428	DNA-directed RNA polymerase complex
0.37	GO:0005667	transcription factor complex
0.36	GO:0070013	intracellular organelle lumen
0.35	GO:0005811	lipid droplet
0.34	GO:0044446	intracellular organelle part
0.34	GO:0048476	Holliday junction resolvase complex
0.34	GO:0000151	ubiquitin ligase complex
0.34	GO:0005938	cell cortex
0.34	GO:0005887	integral component of plasma membrane

0.49

EC:3.1.4.17

GO:0004114

tr|T1FRV4|T1FRV4_HELRO
Uncharacterized protein
Search

tr|T1FRV5|T1FRV5_HELRO
Uncharacterized protein
Search

tr|T1FRV6|T1FRV6_HELRO
Uncharacterized protein
Search

tr|T1FRV7|T1FRV7_HELRO
Uncharacterized protein
Search

tr|T1FRV8|T1FRV8_HELRO
Uncharacterized protein
Search

tr|T1FRV9|T1FRV9_HELRO
Uncharacterized protein
Search

tr|T1FRW0|T1FRW0_HELRO
Uncharacterized protein
Search

tr|T1FRW1|T1FRW1_HELRO
Uncharacterized protein
Search

tr|T1FRW2|T1FRW2_HELRO
Uncharacterized protein
Search

tr|T1FRW3|T1FRW3_HELRO
Uncharacterized protein
Search

tr|T1FRW4|T1FRW4_HELRO
Uncharacterized protein
Search

tr|T1FRW5|T1FRW5_HELRO
Uncharacterized protein
Search

tr|T1FRW6|T1FRW6_HELRO
Uncharacterized protein
Search

0.82	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.54	GO:0006915	apoptotic process
0.45	GO:0043066	negative regulation of apoptotic process
0.41	GO:0032480	negative regulation of type I interferon production
0.41	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway
0.35	GO:0006811	ion transport

0.75	GO:0019900	kinase binding
0.42	GO:0046872	metal ion binding
0.39	GO:0043130	ubiquitin binding

0.43	GO:0070062	extracellular exosome
0.37	GO:0005829	cytosol
0.30	GO:0016020	membrane

tr|T1FRW7|T1FRW7_HELRO
Galactose-1-phosphate uridylyltransferase
Search

0.56	Galactose-1-phosphate uridylyltransferase

0.82	GO:0033499	galactose catabolic process via UDP-galactose
0.45	GO:0033501	galactose homeostasis
0.42	GO:0008344	adult locomotory behavior
0.39	GO:0006011	UDP-glucose metabolic process
0.37	GO:0009227	nucleotide-sugar catabolic process
0.37	GO:0061623	glycolytic process from galactose
0.34	GO:0052574	UDP-D-galactose biosynthetic process
0.34	GO:0042125	protein galactosylation
0.33	GO:0006508	proteolysis
0.33	GO:0046835	carbohydrate phosphorylation

0.81	GO:0008108	UDP-glucose:hexose-1-phosphate uridylyltransferase activity
0.63	GO:0008270	zinc ion binding
0.35	GO:0005534	galactose binding
0.34	GO:0004177	aminopeptidase activity
0.34	GO:0005536	glucose binding
0.34	GO:0004335	galactokinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.38	GO:0005794	Golgi apparatus
0.30	GO:0016020	membrane

0.81	EC:2.7.7.12	GO:0008108
0.81	KEGG:R00955	GO:0008108

tr|T1FRW8|T1FRW8_HELRO
Uncharacterized protein
Search

0.74	GO:0007018	microtubule-based movement
0.60	GO:0035556	intracellular signal transduction
0.60	GO:0043547	positive regulation of GTPase activity
0.38	GO:0035385	Roundabout signaling pathway
0.38	GO:0030048	actin filament-based movement
0.37	GO:0035023	regulation of Rho protein signal transduction
0.36	GO:0006468	protein phosphorylation
0.34	GO:0007605	sensory perception of sound
0.34	GO:0060088	auditory receptor cell stereocilium organization
0.34	GO:0090103	cochlea morphogenesis

0.74	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.74	GO:0003779	actin binding
0.60	GO:0005096	GTPase activator activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0046872	metal ion binding
0.40	GO:0000146	microfilament motor activity
0.39	GO:0048495	Roundabout binding

0.77	GO:0016459	myosin complex
0.38	GO:0005884	actin filament
0.37	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0005938	cell cortex
0.36	GO:0005829	cytosol
0.35	GO:0032433	filopodium tip
0.34	GO:0032426	stereocilium tip
0.34	GO:0001917	photoreceptor inner segment
0.33	GO:0001750	photoreceptor outer segment
0.33	GO:0005634	nucleus

0.35

GO:0016887

tr|T1FRW9|T1FRW9_HELRO
Uncharacterized protein
Search

tr|T1FRX0|T1FRX0_HELRO
Uncharacterized protein
Search

0.49	GO:0060255	regulation of macromolecule metabolic process
0.48	GO:0031326	regulation of cellular biosynthetic process
0.48	GO:0051171	regulation of nitrogen compound metabolic process
0.48	GO:0080090	regulation of primary metabolic process
0.48	GO:0009734	auxin-activated signaling pathway
0.42	GO:0031631	negative regulation of synaptic vesicle fusion to presynaptic active zone membrane
0.41	GO:0006928	movement of cell or subcellular component
0.41	GO:0046665	amnioserosa maintenance
0.41	GO:0006351	transcription, DNA-templated
0.41	GO:0007516	hemocyte development

0.48	GO:0140110	transcription regulator activity
0.44	GO:0004965	G-protein coupled GABA receptor activity
0.43	GO:0005515	protein binding
0.43	GO:0043565	sequence-specific DNA binding
0.41	GO:0003777	microtubule motor activity
0.40	GO:0008270	zinc ion binding
0.39	GO:0004672	protein kinase activity
0.39	GO:0016758	transferase activity, transferring hexosyl groups
0.39	GO:0030554	adenyl nucleotide binding
0.39	GO:0097367	carbohydrate derivative binding

0.46	GO:0005634	nucleus
0.42	GO:0043234	protein complex
0.42	GO:0044446	intracellular organelle part
0.41	GO:0038039	G-protein coupled receptor heterodimeric complex
0.41	GO:0005856	cytoskeleton
0.40	GO:0070013	intracellular organelle lumen
0.39	GO:0030134	COPII-coated ER to Golgi transport vesicle
0.39	GO:0030133	transport vesicle
0.39	GO:0012506	vesicle membrane
0.39	GO:0048475	coated membrane

0.39	EC:2.4.1	GO:0016758
0.37	KEGG:R00894	GO:0004357

tr|T1FRX1|T1FRX1_HELRO
Uncharacterized protein
Search

tr|T1FRX2|T1FRX2_HELRO
Uncharacterized protein
Search

0.86	LIM zinc-binding domain-containing Nebulette-like

0.43

GO:0048747

muscle fiber development

0.55	GO:0003779	actin binding
0.48	GO:0046872	metal ion binding

0.35	GO:0030018	Z disc
0.30	GO:0044425	membrane part

tr|T1FRX3|T1FRX3_HELRO
Uncharacterized protein
Search

0.50	GO:0006352	DNA-templated transcription, initiation
0.47	GO:0006413	translational initiation
0.45	GO:0035335	peptidyl-tyrosine dephosphorylation

0.54	GO:0005515	protein binding
0.48	GO:0003743	translation initiation factor activity
0.45	GO:0004725	protein tyrosine phosphatase activity

0.57	GO:0046695	SLIK (SAGA-like) complex
0.56	GO:0000124	SAGA complex
0.55	GO:0005669	transcription factor TFIID complex
0.36	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.45

GO:0004725

tr|T1FRX4|T1FRX4_HELRO
Uncharacterized protein
Search

0.56	GO:0060255	regulation of macromolecule metabolic process
0.55	GO:0007143	female meiotic nuclear division
0.53	GO:0048477	oogenesis
0.53	GO:0010923	negative regulation of phosphatase activity
0.50	GO:0006302	double-strand break repair

0.57

GO:0003723

RNA binding

0.76	GO:0005777	peroxisome
0.48	GO:0005794	Golgi apparatus
0.30	GO:0016020	membrane

tr|T1FRX5|T1FRX5_HELRO
Uncharacterized protein
Search

0.48	GO:0034968	histone lysine methylation
0.40	GO:0006468	protein phosphorylation
0.40	GO:0007165	signal transduction
0.39	GO:0018344	protein geranylgeranylation
0.38	GO:0031032	actomyosin structure organization
0.37	GO:0009190	cyclic nucleotide biosynthetic process
0.36	GO:0046058	cAMP metabolic process
0.36	GO:0022607	cellular component assembly
0.35	GO:0051639	actin filament network formation
0.35	GO:0020033	antigenic variation

0.48	GO:0018024	histone-lysine N-methyltransferase activity
0.40	GO:0004674	protein serine/threonine kinase activity
0.39	GO:0008318	protein prenyltransferase activity
0.38	GO:0003779	actin binding
0.38	GO:0046872	metal ion binding
0.37	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0016849	phosphorus-oxygen lyase activity
0.37	GO:0003723	RNA binding

0.59	GO:0097610	cell surface furrow
0.57	GO:0032155	cell division site part
0.54	GO:0005938	cell cortex
0.41	GO:0005634	nucleus
0.39	GO:0005968	Rab-protein geranylgeranyltransferase complex
0.35	GO:0032432	actin filament bundle
0.35	GO:0010494	cytoplasmic stress granule
0.35	GO:0005884	actin filament
0.35	GO:0005886	plasma membrane
0.33	GO:0005694	chromosome

0.48

GO:0018024

tr|T1FRX6|T1FRX6_HELRO
Uncharacterized protein
Search

tr|T1FRX7|T1FRX7_HELRO
Uncharacterized protein
Search

tr|T1FRX8|T1FRX8_HELRO
Uncharacterized protein
Search

tr|T1FRX9|T1FRX9_HELRO
Uncharacterized protein
Search

tr|T1FRY0|T1FRY0_HELRO
Uncharacterized protein
Search

0.48	GO:0042953	lipoprotein transport
0.46	GO:0006898	receptor-mediated endocytosis
0.42	GO:0048168	regulation of neuronal synaptic plasticity
0.40	GO:0006508	proteolysis
0.36	GO:0001867	complement activation, lectin pathway

0.64	GO:0005509	calcium ion binding
0.47	GO:0042803	protein homodimerization activity
0.43	GO:0004222	metalloendopeptidase activity
0.35	GO:0008270	zinc ion binding
0.34	GO:0004252	serine-type endopeptidase activity

0.50	GO:0005903	brush border
0.49	GO:0016324	apical plasma membrane
0.49	GO:0030139	endocytic vesicle
0.49	GO:0070062	extracellular exosome
0.49	GO:0005905	clathrin-coated pit
0.47	GO:0005768	endosome
0.46	GO:0005794	Golgi apparatus
0.45	GO:0005783	endoplasmic reticulum
0.30	GO:0016021	integral component of membrane

0.43

GO:0004222

tr|T1FRY1|T1FRY1_HELRO
Uncharacterized protein
Search

tr|T1FRY2|T1FRY2_HELRO
Uncharacterized protein
Search

0.47	GO:0007275	multicellular organism development
0.46	GO:0007219	Notch signaling pathway
0.45	GO:0035583	sequestering of TGFbeta in extracellular matrix
0.44	GO:0061430	bone trabecula morphogenesis
0.43	GO:0030501	positive regulation of bone mineralization
0.43	GO:0045669	positive regulation of osteoblast differentiation
0.42	GO:0030154	cell differentiation
0.41	GO:0048646	anatomical structure formation involved in morphogenesis
0.40	GO:0030198	extracellular matrix organization
0.40	GO:0006508	proteolysis

0.70	GO:0005509	calcium ion binding
0.54	GO:0005201	extracellular matrix structural constituent
0.43	GO:0004222	metalloendopeptidase activity
0.40	GO:0008270	zinc ion binding
0.39	GO:0042802	identical protein binding
0.38	GO:0046983	protein dimerization activity
0.37	GO:0008061	chitin binding
0.37	GO:0004872	receptor activity
0.36	GO:0061134	peptidase regulator activity
0.35	GO:0005112	Notch binding

0.53	GO:0031012	extracellular matrix
0.41	GO:0005903	brush border
0.40	GO:0099512	supramolecular fiber
0.40	GO:0016324	apical plasma membrane
0.40	GO:0030139	endocytic vesicle
0.40	GO:0070062	extracellular exosome
0.40	GO:0005905	clathrin-coated pit
0.39	GO:0005768	endosome
0.38	GO:0005794	Golgi apparatus
0.38	GO:0005783	endoplasmic reticulum

0.43

GO:0004222

tr|T1FRY3|T1FRY3_HELRO
Uncharacterized protein
Search

tr|T1FRY4|T1FRY4_HELRO
Uncharacterized protein
Search

tr|T1FRY5|T1FRY5_HELRO
Uncharacterized protein
Search

tr|T1FRY6|T1FRY6_HELRO
Uncharacterized protein
Search

0.35	GO:0001558	regulation of cell growth
0.34	GO:0060612	adipose tissue development
0.34	GO:0051647	nucleus localization
0.34	GO:0030856	regulation of epithelial cell differentiation
0.34	GO:0045444	fat cell differentiation
0.34	GO:0019915	lipid storage
0.34	GO:0007283	spermatogenesis
0.33	GO:0006629	lipid metabolic process
0.33	GO:0006396	RNA processing
0.32	GO:0055114	oxidation-reduction process

0.34	GO:0004000	adenosine deaminase activity
0.33	GO:0008270	zinc ion binding
0.33	GO:0005515	protein binding
0.32	GO:0003723	RNA binding
0.32	GO:0016491	oxidoreductase activity

0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.34

EC:3.5.4.4

GO:0004000

tr|T1FRY7|T1FRY7_HELRO
Uncharacterized protein
Search

0.49	Serine/threonine-protein kinase spk-1

0.63	GO:0006468	protein phosphorylation
0.36	GO:0000245	spliceosomal complex assembly
0.35	GO:0050684	regulation of mRNA processing
0.34	GO:0010506	regulation of autophagy
0.34	GO:0007519	skeletal muscle tissue development
0.34	GO:0035556	intracellular signal transduction
0.32	GO:0055085	transmembrane transport

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.34	GO:0005615	extracellular space
0.34	GO:0005634	nucleus
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|T1FRY8|T1FRY8_HELRO
Uncharacterized protein
Search

0.44	GO:0034126	positive regulation of MyD88-dependent toll-like receptor signaling pathway
0.43	GO:0016567	protein ubiquitination
0.43	GO:0045880	positive regulation of smoothened signaling pathway
0.42	GO:0071596	ubiquitin-dependent protein catabolic process via the N-end rule pathway
0.41	GO:0043066	negative regulation of apoptotic process
0.36	GO:0010029	regulation of seed germination
0.36	GO:0050994	regulation of lipid catabolic process
0.36	GO:0009737	response to abscisic acid
0.34	GO:0006723	cuticle hydrocarbon biosynthetic process
0.34	GO:0010025	wax biosynthetic process

0.57	GO:0008270	zinc ion binding
0.54	GO:0016874	ligase activity
0.43	GO:0061630	ubiquitin protein ligase activity
0.34	GO:0018812	3-hydroxyacyl-CoA dehydratase activity

0.39	GO:0000151	ubiquitin ligase complex
0.39	GO:0005829	cytosol
0.33	GO:0030176	integral component of endoplasmic reticulum membrane
0.33	GO:0005634	nucleus

0.54

GO:0016874

tr|T1FRY9|T1FRY9_HELRO
Uncharacterized protein
Search

0.58	GO:0035556	intracellular signal transduction
0.47	GO:0061099	negative regulation of protein tyrosine kinase activity
0.36	GO:0007301	female germline ring canal formation
0.36	GO:0042694	muscle cell fate specification
0.35	GO:0048644	muscle organ morphogenesis
0.35	GO:0007498	mesoderm development
0.35	GO:0009952	anterior/posterior pattern specification
0.34	GO:0071897	DNA biosynthetic process

0.45	GO:0004860	protein kinase inhibitor activity
0.44	GO:0017124	SH3 domain binding
0.34	GO:0003887	DNA-directed DNA polymerase activity
0.34	GO:0005509	calcium ion binding
0.33	GO:0046983	protein dimerization activity
0.32	GO:0016787	hydrolase activity

0.43	GO:0005622	intracellular
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.34

GO:0003887

tr|T1FRZ0|T1FRZ0_HELRO
Uncharacterized protein
Search

RPP25

0.95	ribonuclease P protein subunit p25

0.63	GO:0001682	tRNA 5'-leader removal
0.57	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.36	GO:0006364	rRNA processing

0.63	GO:0004526	ribonuclease P activity
0.51	GO:0003676	nucleic acid binding
0.35	GO:0005515	protein binding

0.67	GO:0030681	multimeric ribonuclease P complex
0.66	GO:0000172	ribonuclease MRP complex
0.61	GO:0005815	microtubule organizing center
0.57	GO:0005654	nucleoplasm

0.63

EC:3.1.26.5

GO:0004526

tr|T1FRZ1|T1FRZ1_HELRO
Uncharacterized protein
Search

tr|T1FRZ2|T1FRZ2_HELRO
Uncharacterized protein
Search

0.56	ATP-binding cassette sub-family F member 2

0.61	GO:0016887	ATPase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.61

GO:0016887

tr|T1FRZ3|T1FRZ3_HELRO
Uncharacterized protein
Search

tr|T1FRZ4|T1FRZ4_HELRO
Uncharacterized protein
Search

0.44	GO:0048549	positive regulation of pinocytosis
0.44	GO:0090160	Golgi to lysosome transport
0.43	GO:0034058	endosomal vesicle fusion
0.43	GO:0032439	endosome localization
0.42	GO:0042147	retrograde transport, endosome to Golgi
0.37	GO:0120009	intermembrane lipid transfer
0.34	GO:0035556	intracellular signal transduction
0.33	GO:0006508	proteolysis

0.53	GO:0046872	metal ion binding
0.42	GO:0017137	Rab GTPase binding
0.41	GO:1901981	phosphatidylinositol phosphate binding
0.37	GO:0120013	intermembrane lipid transfer activity
0.34	GO:0004197	cysteine-type endopeptidase activity

0.44	GO:0044352	pinosome
0.42	GO:0030904	retromer complex
0.41	GO:0005769	early endosome
0.41	GO:0010008	endosome membrane
0.39	GO:0005829	cytosol
0.36	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:3.4.22

GO:0004197

tr|T1FRZ5|T1FRZ5_HELRO
Uncharacterized protein
Search

tr|T1FRZ6|T1FRZ6_HELRO
Uncharacterized protein
Search

0.80	Pre-mRNA-splicing factor ISY1

0.85	GO:0000350	generation of catalytic spliceosome for second transesterification step
0.48	GO:0000389	mRNA 3'-splice site recognition
0.34	GO:0006283	transcription-coupled nucleotide-excision repair

0.48	GO:0000384	first spliceosomal transesterification activity
0.34	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.51	GO:0000974	Prp19 complex
0.48	GO:0071020	post-spliceosomal complex
0.47	GO:0071012	catalytic step 1 spliceosome
0.46	GO:0071014	post-mRNA release spliceosomal complex
0.45	GO:0071013	catalytic step 2 spliceosome
0.34	GO:0071011	precatalytic spliceosome
0.34	GO:0005684	U2-type spliceosomal complex
0.33	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

tr|T1FRZ7|T1FRZ7_HELRO
Uncharacterized protein
Search

0.67	Collagen type IV alpha 6 chain

0.44	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.41	GO:0030198	extracellular matrix organization
0.40	GO:0072001	renal system development
0.40	GO:0071230	cellular response to amino acid stimulus
0.39	GO:0007528	neuromuscular junction development
0.39	GO:0048513	animal organ development
0.38	GO:0016525	negative regulation of angiogenesis
0.38	GO:0072577	endothelial cell apoptotic process
0.37	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.37	GO:0001569	branching involved in blood vessel morphogenesis

0.77	GO:0005201	extracellular matrix structural constituent
0.38	GO:0005178	integrin binding
0.37	GO:0048407	platelet-derived growth factor binding
0.34	GO:0003777	microtubule motor activity
0.34	GO:0008017	microtubule binding
0.34	GO:0003779	actin binding
0.33	GO:0001540	amyloid-beta binding
0.33	GO:0008201	heparin binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding

0.77	GO:0005604	basement membrane
0.77	GO:0005581	collagen trimer
0.46	GO:0098645	collagen network
0.37	GO:0005615	extracellular space
0.37	GO:0031594	neuromuscular junction
0.34	GO:0016459	myosin complex
0.34	GO:0005783	endoplasmic reticulum
0.32	GO:0005829	cytosol
0.32	GO:0005887	integral component of plasma membrane

tr|T1FRZ8|T1FRZ8_HELRO
Uncharacterized protein
Search

tr|T1FRZ9|T1FRZ9_HELRO
Uncharacterized protein
Search

0.86	Long-chain-fatty-acid--CoA ligase 4

0.47	GO:0034379	very-low-density lipoprotein particle assembly
0.47	GO:2001247	positive regulation of phosphatidylcholine biosynthetic process
0.46	GO:0001676	long-chain fatty acid metabolic process
0.46	GO:0044539	long-chain fatty acid import
0.46	GO:0042998	positive regulation of Golgi to plasma membrane protein transport
0.44	GO:0051047	positive regulation of secretion
0.41	GO:1900744	regulation of p38MAPK cascade
0.41	GO:0007275	multicellular organism development
0.41	GO:0030513	positive regulation of BMP signaling pathway
0.40	GO:0051896	regulation of protein kinase B signaling

0.54	GO:0016874	ligase activity
0.43	GO:0019901	protein kinase binding
0.43	GO:0019904	protein domain specific binding
0.33	GO:0042302	structural constituent of cuticle

0.47	GO:0005811	lipid droplet
0.43	GO:0048471	perinuclear region of cytoplasm
0.41	GO:0005794	Golgi apparatus
0.41	GO:0005783	endoplasmic reticulum
0.41	GO:0044233	ER-mitochondrion membrane contact site
0.36	GO:0005739	mitochondrion
0.33	GO:0005581	collagen trimer
0.30	GO:0016021	integral component of membrane

0.54

GO:0016874

tr|T1FS00|T1FS00_HELRO
Uncharacterized protein
Search

tr|T1FS01|T1FS01_HELRO
Uncharacterized protein
Search

0.51

GO:0003676

nucleic acid binding

tr|T1FS02|T1FS02_HELRO
Uncharacterized protein
Search

KDM1B

0.96	Lysine-specific histone demethylase 1B

0.59	GO:0032259	methylation
0.57	GO:0006349	regulation of gene expression by genetic imprinting
0.57	GO:0034720	histone H3-K4 demethylation
0.56	GO:0044030	regulation of DNA methylation
0.53	GO:0055114	oxidation-reduction process
0.52	GO:0022412	cellular process involved in reproduction in multicellular organism
0.52	GO:0007276	gamete generation
0.50	GO:0006305	DNA alkylation
0.50	GO:0044728	DNA methylation or demethylation
0.36	GO:0016579	protein deubiquitination

0.63	GO:0008270	zinc ion binding
0.59	GO:0034649	histone demethylase activity (H3-monomethyl-K4 specific)
0.58	GO:0034648	histone demethylase activity (H3-dimethyl-K4 specific)
0.56	GO:0008168	methyltransferase activity
0.55	GO:0003677	DNA binding
0.53	GO:0042393	histone binding
0.50	GO:0071949	FAD binding

0.50	GO:0000786	nucleosome
0.44	GO:0005634	nucleus
0.35	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

0.56

GO:0008168

tr|T1FS03|T1FS03_HELRO
Uncharacterized protein
Search

tr|T1FS04|T1FS04_HELRO
Uncharacterized protein
Search

tr|T1FS05|T1FS05_HELRO
Uncharacterized protein
Search

0.51	GO:0030199	collagen fibril organization
0.50	GO:0002062	chondrocyte differentiation
0.49	GO:0001894	tissue homeostasis
0.49	GO:0048705	skeletal system morphogenesis
0.49	GO:0007605	sensory perception of sound
0.40	GO:0060023	soft palate development
0.39	GO:0001649	osteoblast differentiation
0.38	GO:0010951	negative regulation of endopeptidase activity
0.35	GO:0030574	collagen catabolic process
0.35	GO:0003416	endochondral bone growth

0.71	GO:0005201	extracellular matrix structural constituent
0.42	GO:0042302	structural constituent of cuticle
0.38	GO:0004867	serine-type endopeptidase inhibitor activity
0.34	GO:0046872	metal ion binding
0.34	GO:0042393	histone binding
0.34	GO:0030674	protein binding, bridging
0.33	GO:0004386	helicase activity
0.33	GO:0003676	nucleic acid binding
0.33	GO:0046332	SMAD binding
0.33	GO:0016887	ATPase activity

0.67	GO:0005581	collagen trimer
0.46	GO:0044420	extracellular matrix component
0.45	GO:0005578	proteinaceous extracellular matrix
0.36	GO:0099081	supramolecular polymer
0.35	GO:0016514	SWI/SNF complex
0.34	GO:0005788	endoplasmic reticulum lumen
0.34	GO:0005615	extracellular space
0.33	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.33

GO:0016887

tr|T1FS06|T1FS06_HELRO
Uncharacterized protein
Search

tr|T1FS07|T1FS07_HELRO
Uncharacterized protein
Search

0.55	GO:0048488	synaptic vesicle endocytosis
0.53	GO:0016079	synaptic vesicle exocytosis
0.53	GO:0030100	regulation of endocytosis
0.52	GO:0000281	mitotic cytokinesis
0.51	GO:0007602	phototransduction
0.41	GO:0055114	oxidation-reduction process
0.37	GO:0019511	peptidyl-proline hydroxylation
0.37	GO:0006449	regulation of translational termination

0.55	GO:0004506	squalene monooxygenase activity
0.49	GO:0071949	FAD binding
0.38	GO:0008146	sulfotransferase activity
0.37	GO:0031543	peptidyl-proline dioxygenase activity
0.37	GO:0003723	RNA binding
0.37	GO:0031418	L-ascorbic acid binding
0.35	GO:0005506	iron ion binding

0.51	GO:0098793	presynapse
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.55	EC:1.14.13.132	GO:0004506
0.55	KEGG:R02874	GO:0004506

tr|T1FS08|T1FS08_HELRO
Uncharacterized protein
Search

tr|T1FS09|T1FS09_HELRO
Uncharacterized protein
Search

0.55	GO:0000209	protein polyubiquitination
0.55	GO:0034976	response to endoplasmic reticulum stress
0.54	GO:0034620	cellular response to unfolded protein
0.52	GO:0051865	protein autoubiquitination
0.52	GO:0032092	positive regulation of protein binding
0.52	GO:0010243	response to organonitrogen compound
0.51	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.47	GO:0051259	protein oligomerization
0.46	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.44	GO:0007165	signal transduction

0.57	GO:1990381	ubiquitin-specific protease binding
0.55	GO:1904288	BAT3 complex binding
0.53	GO:0061630	ubiquitin protein ligase activity
0.51	GO:0016874	ligase activity
0.50	GO:0030674	protein binding, bridging
0.49	GO:0051087	chaperone binding
0.47	GO:0042802	identical protein binding
0.44	GO:0004872	receptor activity
0.36	GO:0008270	zinc ion binding
0.35	GO:0003729	mRNA binding

0.53	GO:0036513	Derlin-1 retrotranslocation complex
0.49	GO:0048471	perinuclear region of cytoplasm
0.49	GO:0030176	integral component of endoplasmic reticulum membrane
0.46	GO:0005794	Golgi apparatus
0.38	GO:0030426	growth cone
0.37	GO:0043025	neuronal cell body
0.37	GO:0030425	dendrite
0.36	GO:0005634	nucleus
0.35	GO:0044322	endoplasmic reticulum quality control compartment
0.34	GO:0043233	organelle lumen

0.51

GO:0016874

tr|T1FS10|T1FS10_HELRO
Uncharacterized protein
Search

tr|T1FS11|T1FS11_HELRO
Uncharacterized protein
Search

0.35	GO:1902600	hydrogen ion transmembrane transport
0.35	GO:0022900	electron transport chain

0.36	GO:0015002	heme-copper terminal oxidase activity
0.36	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.35	GO:0015078	hydrogen ion transmembrane transporter activity
0.35	GO:0009055	electron transfer activity

0.35	GO:0044429	mitochondrial part
0.35	GO:0031967	organelle envelope
0.30	GO:0016021	integral component of membrane

0.36

EC:1.9.3

GO:0016676

tr|T1FS12|T1FS12_HELRO
Uncharacterized protein
Search

0.80	GO:0071526	semaphorin-plexin signaling pathway
0.47	GO:0033689	negative regulation of osteoblast proliferation
0.47	GO:0061430	bone trabecula morphogenesis
0.47	GO:0043931	ossification involved in bone maturation
0.47	GO:0050772	positive regulation of axonogenesis
0.46	GO:0007162	negative regulation of cell adhesion
0.46	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling
0.44	GO:0043087	regulation of GTPase activity
0.44	GO:0048812	neuron projection morphogenesis
0.43	GO:0051493	regulation of cytoskeleton organization

0.81	GO:0017154	semaphorin receptor activity
0.47	GO:0032794	GTPase activating protein binding
0.35	GO:0003700	DNA binding transcription factor activity
0.34	GO:0030215	semaphorin receptor binding
0.33	GO:0004075	biotin carboxylase activity
0.33	GO:0005096	GTPase activator activity
0.33	GO:0030248	cellulose binding
0.33	GO:0008270	zinc ion binding
0.33	GO:0004402	histone acetyltransferase activity
0.32	GO:0004190	aspartic-type endopeptidase activity

0.49	GO:0002116	semaphorin receptor complex
0.41	GO:0005887	integral component of plasma membrane
0.33	GO:0005576	extracellular region
0.33	GO:1990745	EARP complex
0.33	GO:0000938	GARP complex
0.33	GO:0005634	nucleus
0.33	GO:0030686	90S preribosome
0.33	GO:0070013	intracellular organelle lumen
0.32	GO:0031248	protein acetyltransferase complex
0.32	GO:0005829	cytosol

0.33

EC:6.3.4.14

GO:0004075

tr|T1FS13|T1FS13_HELRO
Uncharacterized protein
Search

0.70

GO:0005509

calcium ion binding

tr|T1FS14|T1FS14_HELRO
Uncharacterized protein
Search

0.59	GO:0061723	glycophagy
0.57	GO:0061709	reticulophagy
0.56	GO:0030242	autophagy of peroxisome
0.56	GO:0000422	autophagy of mitochondrion
0.55	GO:0000045	autophagosome assembly
0.52	GO:0001934	positive regulation of protein phosphorylation
0.50	GO:0045793	positive regulation of cell size
0.49	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway
0.48	GO:0001889	liver development
0.48	GO:0070304	positive regulation of stress-activated protein kinase signaling cascade

0.54	GO:0032947	protein complex scaffold activity
0.53	GO:0019901	protein kinase binding
0.48	GO:0004035	alkaline phosphatase activity
0.46	GO:0003677	DNA binding

0.56	GO:1990316	Atg1/ULK1 kinase complex
0.55	GO:0034045	phagophore assembly site membrane
0.47	GO:0031965	nuclear membrane
0.43	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.48

EC:3.1.3.1

GO:0004035

tr|T1FS15|T1FS15_HELRO
Transmembrane 9 superfamily member
Search

TM9SF2

0.53	Transmembrane 9 superfamily member

0.46

GO:0061060

negative regulation of peptidoglycan recognition protein signaling pathway

0.37	GO:0005886	plasma membrane
0.36	GO:0010008	endosome membrane
0.36	GO:0070062	extracellular exosome
0.30	GO:0044425	membrane part

tr|T1FS16|T1FS16_HELRO
Uncharacterized protein
Search

tr|T1FS17|T1FS17_HELRO
Uncharacterized protein
Search

tr|T1FS18|T1FS18_HELRO
Uncharacterized protein
Search

tr|T1FS19|T1FS19_HELRO
Uncharacterized protein
Search

0.10	influenza virus NS1A-binding protein homolog A-like

0.64	GO:0016567	protein ubiquitination
0.51	GO:0046528	imaginal disc fusion
0.46	GO:0006511	ubiquitin-dependent protein catabolic process
0.45	GO:0007399	nervous system development
0.42	GO:0006446	regulation of translational initiation
0.42	GO:0043413	macromolecule glycosylation
0.42	GO:0009101	glycoprotein biosynthetic process
0.40	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway
0.40	GO:0002467	germinal center formation
0.39	GO:0050853	B cell receptor signaling pathway

0.60	GO:0004842	ubiquitin-protein transferase activity
0.47	GO:0045480	galactose oxidase activity
0.46	GO:0005515	protein binding
0.44	GO:0008378	galactosyltransferase activity
0.37	GO:0005509	calcium ion binding

0.73	GO:0031463	Cul3-RING ubiquitin ligase complex
0.44	GO:0015629	actin cytoskeleton
0.37	GO:0005829	cytosol
0.36	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.47	EC:1.1.3.9	GO:0045480
0.60	KEGG:R03876	GO:0004842

tr|T1FS20|T1FS20_HELRO
Uncharacterized protein
Search

0.47	GO:0016567	protein ubiquitination
0.46	GO:0000185	activation of MAPKKK activity
0.45	GO:2001235	positive regulation of apoptotic signaling pathway
0.44	GO:0006915	apoptotic process
0.34	GO:0006508	proteolysis
0.34	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.33	GO:0031929	TOR signaling
0.33	GO:0035335	peptidyl-tyrosine dephosphorylation
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:0010467	gene expression

0.58	GO:0008270	zinc ion binding
0.53	GO:0016874	ligase activity
0.45	GO:0004842	ubiquitin-protein transferase activity
0.34	GO:0008233	peptidase activity
0.34	GO:0031624	ubiquitin conjugating enzyme binding
0.34	GO:0043531	ADP binding
0.33	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.33	GO:0061659	ubiquitin-like protein ligase activity
0.33	GO:0004725	protein tyrosine phosphatase activity
0.32	GO:0003735	structural constituent of ribosome

0.43	GO:0000151	ubiquitin ligase complex
0.37	GO:0043231	intracellular membrane-bounded organelle
0.37	GO:0005886	plasma membrane
0.33	GO:0031932	TORC2 complex
0.32	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.53	EC:6	GO:0016874
0.45	KEGG:R03876	GO:0004842

tr|T1FS21|T1FS21_HELRO
Uncharacterized protein
Search

0.53	GO:0046907	intracellular transport
0.53	GO:0048015	phosphatidylinositol-mediated signaling
0.52	GO:0070727	cellular macromolecule localization
0.51	GO:0015031	protein transport
0.49	GO:0046854	phosphatidylinositol phosphorylation
0.40	GO:0044085	cellular component biogenesis
0.40	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.40	GO:0007264	small GTPase mediated signal transduction
0.39	GO:0065009	regulation of molecular function
0.39	GO:0030242	autophagy of peroxisome

0.59	GO:0008536	Ran GTPase binding
0.43	GO:0016301	kinase activity
0.42	GO:0005085	guanyl-nucleotide exchange factor activity
0.40	GO:0030492	hemoglobin binding
0.39	GO:0008320	protein transmembrane transporter activity
0.39	GO:0008139	nuclear localization sequence binding
0.39	GO:0003777	microtubule motor activity
0.39	GO:0008017	microtubule binding
0.38	GO:0005201	extracellular matrix structural constituent
0.38	GO:0017048	Rho GTPase binding

0.51	GO:0005634	nucleus
0.43	GO:0070701	mucus layer
0.40	GO:0020020	food vacuole
0.40	GO:0070013	intracellular organelle lumen
0.40	GO:0012505	endomembrane system
0.40	GO:0034272	phosphatidylinositol 3-kinase complex, class III, type II
0.40	GO:0034271	phosphatidylinositol 3-kinase complex, class III, type I
0.39	GO:0005615	extracellular space
0.39	GO:0030686	90S preribosome
0.39	GO:0000407	phagophore assembly site

0.37

GO:0016773

tr|T1FS22|T1FS22_HELRO
Uncharacterized protein
Search

0.92	arrestin domain-containing protein 4-like

0.61

GO:0007165

signal transduction

tr|T1FS23|T1FS23_HELRO
Uncharacterized protein
Search

tr|T1FS24|T1FS24_HELRO
Uncharacterized protein
Search

0.51	GO:0006357	regulation of transcription by RNA polymerase II
0.44	GO:0006351	transcription, DNA-templated
0.40	GO:1902531	regulation of intracellular signal transduction
0.39	GO:0099120	socially cooperative development
0.38	GO:0044267	cellular protein metabolic process
0.38	GO:0043412	macromolecule modification
0.38	GO:0065009	regulation of molecular function
0.38	GO:0010604	positive regulation of macromolecule metabolic process
0.38	GO:0071840	cellular component organization or biogenesis
0.38	GO:0016201	synaptic target inhibition

0.53	GO:0003712	transcription cofactor activity
0.53	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.41	GO:0003676	nucleic acid binding
0.40	GO:0017048	Rho GTPase binding
0.39	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.38	GO:0004842	ubiquitin-protein transferase activity
0.37	GO:0008146	sulfotransferase activity
0.37	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.36	GO:0015616	DNA translocase activity
0.36	GO:0001102	RNA polymerase II activating transcription factor binding

0.53	GO:0016592	mediator complex
0.41	GO:0071797	LUBAC complex
0.38	GO:0000123	histone acetyltransferase complex
0.37	GO:0000785	chromatin
0.36	GO:0005604	basement membrane
0.36	GO:0001931	uropod
0.36	GO:0031143	pseudopodium
0.36	GO:0044454	nuclear chromosome part
0.35	GO:1905368	peptidase complex
0.35	GO:0005852	eukaryotic translation initiation factor 3 complex

0.37	EC:2.8.2	GO:0008146
0.38	KEGG:R03876	GO:0004842

tr|T1FS25|T1FS25_HELRO
Uncharacterized protein
Search

HGS

0.90	Hepatocyte growth factor-regulated tyrosine kinase substrate

0.67	GO:0006886	intracellular protein transport
0.58	GO:1903543	positive regulation of exosomal secretion
0.57	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway
0.57	GO:0061462	protein localization to lysosome
0.57	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway
0.56	GO:0046426	negative regulation of JAK-STAT cascade
0.56	GO:0010324	membrane invagination
0.55	GO:0007041	lysosomal transport
0.54	GO:0072666	establishment of protein localization to vacuole
0.54	GO:0016525	negative regulation of angiogenesis

0.61	GO:0019904	protein domain specific binding
0.53	GO:0044389	ubiquitin-like protein ligase binding
0.53	GO:0046872	metal ion binding
0.52	GO:0016301	kinase activity
0.38	GO:0140036	ubiquitin-dependent protein binding
0.35	GO:0042802	identical protein binding
0.35	GO:0003735	structural constituent of ribosome

0.68	GO:0032585	multivesicular body membrane
0.65	GO:0031901	early endosome membrane
0.58	GO:0033565	ESCRT-0 complex
0.55	GO:0005829	cytosol
0.53	GO:0005764	lysosome
0.38	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0005938	cell cortex
0.36	GO:0070062	extracellular exosome
0.35	GO:0030141	secretory granule
0.35	GO:0005840	ribosome

tr|T1FS26|T1FS26_HELRO
Uncharacterized protein
Search

tr|T1FS27|T1FS27_HELRO
Uncharacterized protein
Search

tr|T1FS28|T1FS28_HELRO
Uncharacterized protein
Search

tr|T1FS29|T1FS29_HELRO
Uncharacterized protein
Search

tr|T1FS30|T1FS30_HELRO
Uncharacterized protein
Search

tr|T1FS31|T1FS31_HELRO
Uncharacterized protein
Search

CDC27

0.93	Cell division cycle protein 27

0.61	GO:0051301	cell division
0.55	GO:0007091	metaphase/anaphase transition of mitotic cell cycle
0.54	GO:0070979	protein K11-linked ubiquitination
0.36	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.36	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0031145	anaphase-promoting complex-dependent catabolic process
0.35	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.35	GO:0008283	cell proliferation
0.31	GO:0010469	regulation of receptor activity

0.52	GO:0019903	protein phosphatase binding
0.35	GO:0003677	DNA binding
0.33	GO:0005509	calcium ion binding
0.32	GO:0005179	hormone activity

0.51	GO:0005876	spindle microtubule
0.50	GO:0005680	anaphase-promoting complex
0.50	GO:0005813	centrosome
0.47	GO:0005654	nucleoplasm
0.38	GO:0005737	cytoplasm
0.31	GO:0005576	extracellular region

tr|T1FS32|T1FS32_HELRO
Uncharacterized protein
Search

0.77	GO:0007264	small GTPase mediated signal transduction
0.66	GO:0042127	regulation of cell proliferation
0.66	GO:0065009	regulation of molecular function
0.44	GO:0045314	regulation of compound eye photoreceptor development
0.43	GO:0006930	substrate-dependent cell migration, cell extension
0.43	GO:0035099	hemocyte migration
0.43	GO:0007485	imaginal disc-derived male genitalia development
0.43	GO:0016476	regulation of embryonic cell shape
0.43	GO:0007391	dorsal closure
0.43	GO:0030718	germ-line stem cell population maintenance

0.78	GO:0017034	Rap guanyl-nucleotide exchange factor activity
0.66	GO:0005096	GTPase activator activity

0.45	GO:0005622	intracellular
0.43	GO:0016327	apicolateral plasma membrane
0.41	GO:0005912	adherens junction
0.30	GO:0016021	integral component of membrane

tr|T1FS33|T1FS33_HELRO
Uncharacterized protein
Search

0.68	Formin homology 2 domain containing 3b

0.75	GO:0007015	actin filament organization
0.65	GO:0055003	cardiac myofibril assembly
0.62	GO:0045214	sarcomere organization
0.60	GO:0030837	negative regulation of actin filament polymerization

0.60

GO:0030017

sarcomere

tr|T1FS34|T1FS34_HELRO
Uncharacterized protein
Search

tr|T1FS35|T1FS35_HELRO
Uncharacterized protein
Search

tr|T1FS36|T1FS36_HELRO
Uncharacterized protein
Search

tr|T1FS37|T1FS37_HELRO
Uncharacterized protein
Search

tr|T1FS38|T1FS38_HELRO
Uncharacterized protein
Search

tr|T1FS39|T1FS39_HELRO
Uncharacterized protein
Search

0.46

GO:0005509

calcium ion binding

0.30

GO:0044425

membrane part

tr|T1FS40|T1FS40_HELRO
Uncharacterized protein
Search

0.46	GO:0006030	chitin metabolic process
0.41	GO:0005975	carbohydrate metabolic process
0.41	GO:0007399	nervous system development
0.40	GO:0030154	cell differentiation
0.40	GO:0019226	transmission of nerve impulse
0.40	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.40	GO:0007155	cell adhesion
0.40	GO:0050808	synapse organization
0.39	GO:0120036	plasma membrane bounded cell projection organization
0.39	GO:0035725	sodium ion transmembrane transport

0.48	GO:0008061	chitin binding
0.45	GO:0030246	carbohydrate binding
0.42	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.40	GO:0005509	calcium ion binding
0.39	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.39	GO:0005272	sodium channel activity
0.38	GO:0001871	pattern binding
0.38	GO:0031406	carboxylic acid binding
0.37	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.37	GO:0004713	protein tyrosine kinase activity

0.48	GO:0005576	extracellular region
0.36	GO:0005856	cytoskeleton
0.36	GO:0097458	neuron part
0.36	GO:0005927	muscle tendon junction
0.36	GO:0045169	fusome
0.35	GO:0099738	cell cortex region
0.35	GO:0005634	nucleus
0.35	GO:0030175	filopodium
0.35	GO:0005618	cell wall
0.35	GO:0030427	site of polarized growth

0.42

GO:0004553

tr|T1FS41|T1FS41_HELRO
Uncharacterized protein
Search

0.52	GO:0043043	peptide biosynthetic process
0.49	GO:0044267	cellular protein metabolic process
0.48	GO:0010467	gene expression
0.47	GO:0009059	macromolecule biosynthetic process

0.55

GO:0003735

structural constituent of ribosome

0.53	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

tr|T1FS42|T1FS42_HELRO
Elongation of very long chain fatty acids protein
Search

0.28	Elongation of very long chain fatty acids protein

0.68	GO:0006633	fatty acid biosynthetic process
0.47	GO:0000038	very long-chain fatty acid metabolic process
0.43	GO:0030148	sphingolipid biosynthetic process
0.38	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process
0.38	GO:0033559	unsaturated fatty acid metabolic process
0.34	GO:0001676	long-chain fatty acid metabolic process

0.80	GO:0102756	very-long-chain 3-ketoacyl-CoA synthase activity
0.80	GO:0102338	3-oxo-lignoceronyl-CoA synthase activity
0.80	GO:0102336	3-oxo-arachidoyl-CoA synthase activity
0.80	GO:0102337	3-oxo-cerotoyl-CoA synthase activity
0.47	GO:0009922	fatty acid elongase activity
0.35	GO:0003723	RNA binding

0.42	GO:0005783	endoplasmic reticulum
0.42	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.41	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.80

EC:2.3.1.199

GO:0102338

tr|T1FS43|T1FS43_HELRO
Uncharacterized protein
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tr|T1FS44|T1FS44_HELRO
Uncharacterized protein
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BRIX1

0.83	Brix domain-containing protein 2

0.62	GO:0000027	ribosomal large subunit assembly
0.36	GO:0006886	intracellular protein transport
0.36	GO:0061025	membrane fusion
0.36	GO:0016192	vesicle-mediated transport
0.35	GO:0006351	transcription, DNA-templated
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:0010468	regulation of gene expression

0.50	GO:0003723	RNA binding
0.38	GO:0005484	SNAP receptor activity
0.34	GO:0003677	DNA binding

0.72	GO:0005730	nucleolus
0.47	GO:0030687	preribosome, large subunit precursor
0.30	GO:0016020	membrane

tr|T1FS45|T1FS45_HELRO
Uncharacterized protein
Search

0.11	Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B (Fragment)

0.60	GO:0005975	carbohydrate metabolic process
0.42	GO:0006487	protein N-linked glycosylation
0.34	GO:0006457	protein folding
0.32	GO:0016567	protein ubiquitination
0.32	GO:0006470	protein dephosphorylation

0.69	GO:0016758	transferase activity, transferring hexosyl groups
0.41	GO:0008194	UDP-glycosyltransferase activity
0.37	GO:0140103	catalytic activity, acting on a glycoprotein
0.34	GO:0046872	metal ion binding
0.34	GO:0051082	unfolded protein binding
0.32	GO:0004842	ubiquitin-protein transferase activity
0.32	GO:0016874	ligase activity
0.32	GO:0004721	phosphoprotein phosphatase activity

0.36	GO:0012505	endomembrane system
0.36	GO:0098588	bounding membrane of organelle
0.35	GO:0031984	organelle subcompartment
0.34	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0044444	cytoplasmic part
0.30	GO:0016021	integral component of membrane

0.69	EC:2.4.1	GO:0016758
0.32	KEGG:R03876	GO:0004842

tr|T1FS46|T1FS46_HELRO
Uncharacterized protein
Search

0.68	Bifunctional arginine demethylase and lysyl-hydroxylase PSR

0.39	GO:0010172	embryonic body morphogenesis
0.39	GO:0032259	methylation
0.38	GO:0032956	regulation of actin cytoskeleton organization
0.38	GO:0098609	cell-cell adhesion
0.36	GO:0006260	DNA replication
0.34	GO:0000413	protein peptidyl-prolyl isomerization

0.39	GO:0008168	methyltransferase activity
0.38	GO:0045296	cadherin binding
0.34	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.34	GO:0003676	nucleic acid binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.39	GO:0005913	cell-cell adherens junction
0.30	GO:0016020	membrane

0.39

GO:0008168

tr|T1FS47|T1FS47_HELRO
Uncharacterized protein
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tr|T1FS48|T1FS48_HELRO
Uncharacterized protein
Search

EXD2

0.90	Exonuclease 3'-5' domain-containing protein 2

0.64	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.54	GO:0000729	DNA double-strand break processing
0.49	GO:0000724	double-strand break repair via homologous recombination
0.39	GO:0016444	somatic cell DNA recombination
0.33	GO:0006417	regulation of translation

0.71	GO:0008408	3'-5' exonuclease activity
0.53	GO:0008297	single-stranded DNA exodeoxyribonuclease activity
0.51	GO:0003676	nucleic acid binding
0.36	GO:0008852	exodeoxyribonuclease I activity
0.33	GO:0005515	protein binding

0.39	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.36

EC:3.1.11.1

GO:0008852

tr|T1FS49|T1FS49_HELRO
Uncharacterized protein
Search

tr|T1FS50|T1FS50_HELRO
Uncharacterized protein
Search

0.66	GO:0030001	metal ion transport
0.56	GO:0006882	cellular zinc ion homeostasis
0.55	GO:0055085	transmembrane transport
0.50	GO:0072511	divalent inorganic cation transport
0.47	GO:1903615	positive regulation of protein tyrosine phosphatase activity
0.47	GO:0050861	positive regulation of B cell receptor signaling pathway
0.46	GO:0002903	negative regulation of B cell apoptotic process
0.45	GO:0030890	positive regulation of B cell proliferation
0.39	GO:0042074	cell migration involved in gastrulation
0.38	GO:0001837	epithelial to mesenchymal transition

0.69	GO:0046873	metal ion transmembrane transporter activity
0.53	GO:0072509	divalent inorganic cation transmembrane transporter activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.51	GO:0031258	lamellipodium membrane
0.45	GO:0005887	integral component of plasma membrane
0.43	GO:0005783	endoplasmic reticulum
0.34	GO:0009986	cell surface

tr|T1FS51|T1FS51_HELRO
Poly [ADP-ribose] polymerase
Search

0.28	Poly [ADP-ribose] polymerase

0.83	GO:0006471	protein ADP-ribosylation
0.42	GO:0006273	lagging strand elongation
0.41	GO:0051103	DNA ligation involved in DNA repair
0.36	GO:0006302	double-strand break repair
0.36	GO:0043043	peptide biosynthetic process
0.35	GO:0010467	gene expression

0.82	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.41	GO:0003910	DNA ligase (ATP) activity
0.40	GO:0051287	NAD binding
0.39	GO:0008270	zinc ion binding
0.37	GO:0003735	structural constituent of ribosome
0.37	GO:0003677	DNA binding

0.38	GO:0005634	nucleus
0.37	GO:0005840	ribosome

0.82

GO:0003950

tr|T1FS52|T1FS52_HELRO
Uncharacterized protein
Search

0.58	GO:0006471	protein ADP-ribosylation
0.42	GO:0010332	response to gamma radiation
0.42	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage
0.41	GO:0006273	lagging strand elongation
0.41	GO:0051103	DNA ligation involved in DNA repair
0.40	GO:0043069	negative regulation of programmed cell death
0.39	GO:0006468	protein phosphorylation
0.38	GO:0018205	peptidyl-lysine modification
0.38	GO:0060255	regulation of macromolecule metabolic process
0.38	GO:0007018	microtubule-based movement

0.57	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.43	GO:0003723	RNA binding
0.40	GO:0003910	DNA ligase (ATP) activity
0.39	GO:0004672	protein kinase activity
0.38	GO:0003700	DNA binding transcription factor activity
0.38	GO:0032559	adenyl ribonucleotide binding
0.38	GO:0008923	lysine decarboxylase activity
0.38	GO:0008144	drug binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0003777	microtubule motor activity

0.40	GO:0005634	nucleus
0.38	GO:0005694	chromosome
0.37	GO:0020011	apicoplast
0.36	GO:0030688	preribosome, small subunit precursor
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.57	EC:2.4.2.30	GO:0003950
0.38	KEGG:R00462	GO:0008923

tr|T1FS53|T1FS53_HELRO
Uncharacterized protein
Search

CCNC

0.89

Cyclin C

0.76	GO:0045859	regulation of protein kinase activity
0.46	GO:0060429	epithelium development
0.45	GO:0045498	sex comb development
0.45	GO:0061318	renal filtration cell differentiation
0.44	GO:0035285	appendage segmentation
0.44	GO:0061005	cell differentiation involved in kidney development
0.44	GO:0032835	glomerulus development
0.44	GO:1901409	positive regulation of phosphorylation of RNA polymerase II C-terminal domain
0.44	GO:0022416	chaeta development
0.43	GO:0034472	snRNA 3'-end processing

0.82	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity
0.42	GO:0001104	RNA polymerase II transcription cofactor activity
0.38	GO:0016301	kinase activity
0.34	GO:0004605	phosphatidate cytidylyltransferase activity
0.34	GO:0005515	protein binding
0.33	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.32	GO:0140096	catalytic activity, acting on a protein

0.77	GO:0016592	mediator complex
0.43	GO:0000307	cyclin-dependent protein kinase holoenzyme complex

0.82

GO:0016538

tr|T1FS54|T1FS54_HELRO
Uncharacterized protein
Search

tr|T1FS55|T1FS55_HELRO
Uncharacterized protein
Search

tr|T1FS56|T1FS56_HELRO
Uncharacterized protein
Search

PFAS

0.49	Phosphoribosylformylglycinamidine synthase

0.70	GO:0006189	'de novo' IMP biosynthetic process
0.37	GO:0006541	glutamine metabolic process
0.36	GO:0042493	response to drug

0.77	GO:0004642	phosphoribosylformylglycinamidine synthase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0046872	metal ion binding
0.33	GO:0016740	transferase activity

0.37	GO:0070062	extracellular exosome
0.36	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.77	EC:6.3.5.3	GO:0004642
0.77	KEGG:R04463	GO:0004642

tr|T1FS57|T1FS57_HELRO
Uncharacterized protein
Search

COPS4

0.85	COP9 constitutive photomorphogenic homolog subunit 4

0.47	GO:0000338	protein deneddylation
0.34	GO:0043687	post-translational protein modification
0.34	GO:0000715	nucleotide-excision repair, DNA damage recognition
0.34	GO:0006283	transcription-coupled nucleotide-excision repair

0.48	GO:0019784	NEDD8-specific protease activity
0.34	GO:0005515	protein binding

0.81	GO:0008180	COP9 signalosome
0.42	GO:0008021	synaptic vesicle
0.42	GO:0005829	cytosol
0.40	GO:0030054	cell junction
0.37	GO:0016607	nuclear speck
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

tr|T1FS58|T1FS58_HELRO
Uncharacterized protein
Search

EFHD2

0.93	EF hand-containing protein 1

0.42	GO:0048856	anatomical structure development
0.41	GO:0120036	plasma membrane bounded cell projection organization
0.40	GO:0030154	cell differentiation
0.39	GO:0032501	multicellular organismal process
0.35	GO:0006413	translational initiation
0.33	GO:0006508	proteolysis

0.70	GO:0005509	calcium ion binding
0.47	GO:0045296	cadherin binding
0.35	GO:0003743	translation initiation factor activity
0.33	GO:0004252	serine-type endopeptidase activity

0.42	GO:0005927	muscle tendon junction
0.38	GO:0045121	membrane raft
0.38	GO:0031966	mitochondrial membrane
0.38	GO:0019866	organelle inner membrane
0.35	GO:0005886	plasma membrane
0.34	GO:0070062	extracellular exosome

0.33

GO:0004252

tr|T1FS59|T1FS59_HELRO
Uncharacterized protein
Search

MLH1

0.92	MutL homolog 1, colon cancer, nonpolyposis type 2

0.75	GO:0006298	mismatch repair
0.73	GO:0043060	meiotic metaphase I plate congression
0.71	GO:0016446	somatic hypermutation of immunoglobulin genes
0.70	GO:0051257	meiotic spindle midzone assembly
0.69	GO:0007140	male meiotic nuclear division
0.69	GO:0007129	synapsis
0.69	GO:0048298	positive regulation of isotype switching to IgA isotypes
0.68	GO:0045950	negative regulation of mitotic recombination
0.68	GO:0048304	positive regulation of isotype switching to IgG isotypes
0.68	GO:0016321	female meiosis chromosome segregation

0.76	GO:0030983	mismatched DNA binding
0.70	GO:0032407	MutSalpha complex binding
0.59	GO:0003682	chromatin binding
0.59	GO:0003697	single-stranded DNA binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0016887	ATPase activity

0.82	GO:0032300	mismatch repair complex
0.71	GO:0005712	chiasma
0.71	GO:0005715	late recombination nodule
0.67	GO:0000795	synaptonemal complex
0.67	GO:0001673	male germ cell nucleus
0.55	GO:0005654	nucleoplasm
0.30	GO:0016021	integral component of membrane

0.44

GO:0016887

tr|T1FS60|T1FS60_HELRO
Uncharacterized protein
Search

RBPJ

0.92	Recombination signal binding protein for immunoglobulin kappa J region b

0.72	GO:0072148	epithelial cell fate commitment
0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.69	GO:0060840	artery development
0.69	GO:0001756	somitogenesis
0.68	GO:1905068	positive regulation of canonical Wnt signaling pathway involved in heart development
0.68	GO:1901189	positive regulation of ephrin receptor signaling pathway
0.68	GO:0035270	endocrine system development
0.67	GO:1901295	regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment
0.67	GO:0060485	mesenchyme development
0.66	GO:0060486	Clara cell differentiation

0.80	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.80	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.65	GO:0001103	RNA polymerase II repressing transcription factor binding
0.62	GO:0047485	protein N-terminus binding
0.61	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.57	GO:0003682	chromatin binding
0.36	GO:0032403	protein complex binding

0.68	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex
0.61	GO:0005634	nucleus
0.61	GO:0017053	transcriptional repressor complex
0.56	GO:0005667	transcription factor complex
0.53	GO:0070013	intracellular organelle lumen
0.48	GO:0043232	intracellular non-membrane-bounded organelle
0.47	GO:0044446	intracellular organelle part
0.41	GO:0005737	cytoplasm
0.36	GO:0032993	protein-DNA complex

tr|T1FS61|T1FS61_HELRO
Uncharacterized protein
Search

tr|T1FS62|T1FS62_HELRO
Uncharacterized protein
Search

0.68	GO:0007018	microtubule-based movement
0.47	GO:0035315	hair cell differentiation
0.46	GO:0048563	post-embryonic animal organ morphogenesis
0.46	GO:0007605	sensory perception of sound
0.46	GO:0030048	actin filament-based movement
0.45	GO:0001845	phagolysosome assembly
0.45	GO:0051904	pigment granule transport
0.45	GO:0007423	sensory organ development
0.45	GO:0120036	plasma membrane bounded cell projection organization
0.44	GO:0060563	neuroepithelial cell differentiation

0.69	GO:0003777	microtubule motor activity
0.69	GO:0051015	actin filament binding
0.69	GO:0008017	microtubule binding
0.52	GO:0032559	adenyl ribonucleotide binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0030898	actin-dependent ATPase activity
0.44	GO:0000146	microfilament motor activity
0.42	GO:0019904	protein domain specific binding
0.41	GO:0032027	myosin light chain binding

0.71	GO:0016459	myosin complex
0.46	GO:0098858	actin-based cell projection
0.45	GO:0045177	apical part of cell
0.44	GO:0032391	photoreceptor connecting cilium
0.44	GO:0032421	stereocilium bundle
0.44	GO:0042470	melanosome
0.42	GO:0098590	plasma membrane region
0.42	GO:0045202	synapse
0.40	GO:0070825	micropyle
0.40	GO:0035182	female germline ring canal outer rim

tr|T1FS63|T1FS63_HELRO
Uncharacterized protein
Search

0.47	GO:1903506	regulation of nucleic acid-templated transcription
0.47	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.47	GO:0010468	regulation of gene expression
0.42	GO:0006352	DNA-templated transcription, initiation
0.39	GO:0016042	lipid catabolic process
0.38	GO:0035335	peptidyl-tyrosine dephosphorylation
0.38	GO:0048856	anatomical structure development
0.38	GO:0072718	response to cisplatin
0.37	GO:0043949	regulation of cAMP-mediated signaling
0.37	GO:0006325	chromatin organization

0.49	GO:0003700	DNA binding transcription factor activity
0.41	GO:0003676	nucleic acid binding
0.40	GO:0016887	ATPase activity
0.39	GO:0008270	zinc ion binding
0.38	GO:0032559	adenyl ribonucleotide binding
0.38	GO:0004725	protein tyrosine phosphatase activity
0.38	GO:0008144	drug binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.36	GO:0016874	ligase activity

0.40	GO:0043227	membrane-bounded organelle
0.39	GO:0043229	intracellular organelle
0.38	GO:0035032	phosphatidylinositol 3-kinase complex, class III
0.37	GO:0098805	whole membrane
0.37	GO:0044422	organelle part
0.36	GO:0044444	cytoplasmic part
0.36	GO:0030687	preribosome, large subunit precursor
0.36	GO:0031974	membrane-enclosed lumen
0.36	GO:0034708	methyltransferase complex
0.35	GO:0012505	endomembrane system

0.40

GO:0016887

tr|T1FS64|T1FS64_HELRO
Uncharacterized protein
Search

tr|T1FS65|T1FS65_HELRO
Uncharacterized protein
Search

0.43	GO:0048203	vesicle targeting, trans-Golgi to endosome
0.43	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading
0.42	GO:0006464	cellular protein modification process
0.42	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation
0.42	GO:0006508	proteolysis
0.41	GO:0007043	cell-cell junction assembly
0.41	GO:2000146	negative regulation of cell motility
0.41	GO:0050808	synapse organization
0.41	GO:0008033	tRNA processing
0.41	GO:0006030	chitin metabolic process

0.44	GO:0140096	catalytic activity, acting on a protein
0.43	GO:0097367	carbohydrate derivative binding
0.43	GO:0035650	AP-1 adaptor complex binding
0.42	GO:0005509	calcium ion binding
0.42	GO:0017171	serine hydrolase activity
0.41	GO:0043168	anion binding
0.41	GO:0016286	small conductance calcium-activated potassium channel activity
0.41	GO:0005044	scavenger receptor activity
0.41	GO:0051539	4 iron, 4 sulfur cluster binding
0.41	GO:0001871	pattern binding

0.43	GO:0070701	mucus layer
0.39	GO:0005618	cell wall
0.38	GO:0005829	cytosol
0.37	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.39

GO:0016773

tr|T1FS66|T1FS66_HELRO
Uncharacterized protein
Search

tr|T1FS67|T1FS67_HELRO
Uncharacterized protein
Search

0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression
0.43	GO:0034249	negative regulation of cellular amide metabolic process
0.42	GO:0032269	negative regulation of cellular protein metabolic process
0.41	GO:0010558	negative regulation of macromolecule biosynthetic process
0.41	GO:0031327	negative regulation of cellular biosynthetic process
0.41	GO:0034622	cellular macromolecular complex assembly

0.55	GO:0003677	DNA binding
0.45	GO:0003730	mRNA 3'-UTR binding
0.35	GO:0005515	protein binding

0.35

GO:0005737

cytoplasm

tr|T1FS68|T1FS68_HELRO
Uncharacterized protein
Search

tr|T1FS69|T1FS69_HELRO
Uncharacterized protein
Search

tr|T1FS70|T1FS70_HELRO
Uncharacterized protein
Search

tr|T1FS71|T1FS71_HELRO
Uncharacterized protein
Search

0.70	GO:0043401	steroid hormone mediated signaling pathway
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:2001141	regulation of RNA biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.43	GO:0030522	intracellular receptor signaling pathway
0.39	GO:0021982	pineal gland development
0.36	GO:0043059	regulation of forward locomotion
0.36	GO:0043058	regulation of backward locomotion
0.36	GO:0048665	neuron fate specification

0.70	GO:0003707	steroid hormone receptor activity
0.63	GO:0043565	sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.60	GO:0003700	DNA binding transcription factor activity
0.34	GO:0015385	sodium:proton antiporter activity
0.33	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups
0.33	GO:0003729	mRNA binding
0.33	GO:0003856	3-dehydroquinate synthase activity
0.33	GO:0004765	shikimate kinase activity
0.33	GO:0003855	3-dehydroquinate dehydratase activity

0.60	GO:0005634	nucleus
0.33	GO:0000808	origin recognition complex
0.33	GO:0031461	cullin-RING ubiquitin ligase complex
0.32	GO:0043233	organelle lumen
0.30	GO:0016020	membrane

0.33	EC:2.5 EC:2.5.1	GO:0016765
0.33	KEGG:R03083	GO:0003856

tr|T1FS72|T1FS72_HELRO
Uncharacterized protein
Search

0.65	GO:0016567	protein ubiquitination
0.59	GO:0006511	ubiquitin-dependent protein catabolic process
0.41	GO:2000650	negative regulation of sodium ion transmembrane transporter activity
0.41	GO:2000009	negative regulation of protein localization to cell surface
0.41	GO:1901017	negative regulation of potassium ion transmembrane transporter activity
0.41	GO:1903861	positive regulation of dendrite extension
0.40	GO:0060306	regulation of membrane repolarization
0.40	GO:0003254	regulation of membrane depolarization
0.40	GO:0010498	proteasomal protein catabolic process
0.38	GO:0010038	response to metal ion

0.65	GO:0004842	ubiquitin-protein transferase activity
0.62	GO:0061659	ubiquitin-like protein ligase activity
0.54	GO:0051087	chaperone binding
0.46	GO:0016874	ligase activity
0.41	GO:0019870	potassium channel inhibitor activity
0.41	GO:0019871	sodium channel inhibitor activity
0.40	GO:0044325	ion channel binding
0.37	GO:0061650	ubiquitin-like protein conjugating enzyme activity
0.35	GO:0046872	metal ion binding
0.34	GO:0016301	kinase activity

0.35	GO:0005886	plasma membrane
0.34	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm

0.46	EC:6	GO:0016874
0.65	KEGG:R03876	GO:0004842

tr|T1FS73|T1FS73_HELRO
Uncharacterized protein
Search

0.79	GO:0007160	cell-matrix adhesion
0.51	GO:0090528	smooth septate junction assembly
0.37	GO:0007339	binding of sperm to zona pellucida
0.35	GO:0007275	multicellular organism development

0.43	GO:0005509	calcium ion binding
0.37	GO:0050840	extracellular matrix binding
0.35	GO:0005515	protein binding

0.50	GO:0005920	smooth septate junction
0.38	GO:0016327	apicolateral plasma membrane
0.35	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

tr|T1FS74|T1FS74_HELRO
Uncharacterized protein
Search

tr|T1FS75|T1FS75_HELRO
Uncharacterized protein
Search

0.63	GO:0016180	snRNA processing
0.39	GO:0045892	negative regulation of transcription, DNA-templated
0.39	GO:0042276	error-prone translesion synthesis
0.38	GO:0000412	histone peptidyl-prolyl isomerization
0.36	GO:0006511	ubiquitin-dependent protein catabolic process
0.36	GO:0007060	male meiosis chromosome segregation
0.36	GO:0071763	nuclear membrane organization
0.36	GO:0010032	meiotic chromosome condensation
0.36	GO:0070647	protein modification by small protein conjugation or removal
0.36	GO:0051299	centrosome separation

0.52	GO:0003677	DNA binding
0.38	GO:0005528	FK506 binding
0.36	GO:0034511	U3 snoRNA binding
0.36	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.36	GO:0005521	lamin binding
0.35	GO:0016779	nucleotidyltransferase activity
0.35	GO:0005525	GTP binding
0.35	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.35	GO:0061630	ubiquitin protein ligase activity
0.35	GO:0005096	GTPase activator activity

0.63	GO:0032039	integrator complex
0.38	GO:0005730	nucleolus
0.36	GO:0005652	nuclear lamina
0.36	GO:0005700	polytene chromosome
0.35	GO:0016602	CCAAT-binding factor complex
0.35	GO:0030686	90S preribosome
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.36

EC:5.2.1.8

GO:0003755

tr|T1FS76|T1FS76_HELRO
Uncharacterized protein
Search

tr|T1FS77|T1FS77_HELRO
Uncharacterized protein
Search

tr|T1FS78|T1FS78_HELRO
Uncharacterized protein
Search

tr|T1FS79|T1FS79_HELRO
Uncharacterized protein
Search

tr|T1FS80|T1FS80_HELRO
Uncharacterized protein
Search

0.47	GO:0006417	regulation of translation
0.47	GO:0017182	peptidyl-diphthamide metabolic process
0.44	GO:1903506	regulation of nucleic acid-templated transcription
0.43	GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
0.42	GO:0097466	ubiquitin-dependent glycoprotein ERAD pathway
0.42	GO:0006491	N-glycan processing
0.42	GO:0034249	negative regulation of cellular amide metabolic process
0.41	GO:0030968	endoplasmic reticulum unfolded protein response
0.40	GO:0032269	negative regulation of cellular protein metabolic process
0.40	GO:2000113	negative regulation of cellular macromolecule biosynthetic process

0.44	GO:0017178	diphthine-ammonia ligase activity
0.44	GO:0003723	RNA binding
0.43	GO:0003700	DNA binding transcription factor activity
0.41	GO:0046872	metal ion binding
0.41	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
0.37	GO:0043565	sequence-specific DNA binding
0.37	GO:0004672	protein kinase activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.44	GO:0030015	CCR4-NOT core complex
0.43	GO:0000932	P-body
0.40	GO:0005634	nucleus
0.39	GO:0005783	endoplasmic reticulum
0.30	GO:0016020	membrane

0.44	EC:6.3.1.14	GO:0017178
0.44	KEGG:R03613	GO:0017178

tr|T1FS81|T1FS81_HELRO
Uncharacterized protein
Search

tr|T1FS82|T1FS82_HELRO
Uncharacterized protein
Search

tr|T1FS83|T1FS83_HELRO
Uncharacterized protein
Search

tr|T1FS84|T1FS84_HELRO
Uncharacterized protein
Search

0.60	GO:0007165	signal transduction
0.46	GO:0098910	regulation of atrial cardiac muscle cell action potential
0.44	GO:0098907	regulation of SA node cell action potential
0.44	GO:0086070	SA node cell to atrial cardiac muscle cell communication
0.43	GO:0086014	atrial cardiac muscle cell action potential
0.43	GO:0086005	ventricular cardiac muscle cell action potential
0.43	GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
0.43	GO:0060307	regulation of ventricular cardiac muscle cell membrane repolarization
0.43	GO:0003283	atrial septum development
0.43	GO:0086091	regulation of heart rate by cardiac conduction

0.45	GO:0030507	spectrin binding
0.42	GO:0044325	ion channel binding
0.41	GO:0019901	protein kinase binding
0.37	GO:0050839	cell adhesion molecule binding
0.33	GO:0070001	aspartic-type peptidase activity
0.33	GO:0004175	endopeptidase activity

0.42	GO:0016323	basolateral plasma membrane
0.41	GO:0043034	costamere
0.38	GO:0016328	lateral plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1FS85|T1FS85_HELRO
Uncharacterized protein
Search

tr|T1FS86|T1FS86_HELRO
Uncharacterized protein
Search

0.54	Methionine-tRNA synthetase

0.78

GO:0006431

methionyl-tRNA aminoacylation

0.79	GO:0004825	methionine-tRNA ligase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0000049	tRNA binding
0.37	GO:0046872	metal ion binding
0.36	GO:0008080	N-acetyltransferase activity
0.33	GO:0046983	protein dimerization activity

0.48	GO:0005737	cytoplasm
0.37	GO:0043231	intracellular membrane-bounded organelle
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0044446	intracellular organelle part

0.79

EC:6.1.1.10

GO:0004825

tr|T1FS87|T1FS87_HELRO
Uncharacterized protein
Search

tr|T1FS88|T1FS88_HELRO
Phosphate transporter
Search

0.38	Phosphate transporter

0.73	GO:0006817	phosphate ion transport
0.55	GO:0055085	transmembrane transport
0.39	GO:0006814	sodium ion transport

0.75	GO:0005315	inorganic phosphate transmembrane transporter activity
0.43	GO:0015319	sodium:inorganic phosphate symporter activity

0.38

GO:0005887

integral component of plasma membrane

tr|T1FS89|T1FS89_HELRO
Uncharacterized protein
Search

0.48	GO:0007186	G-protein coupled receptor signaling pathway
0.48	GO:0007166	cell surface receptor signaling pathway
0.41	GO:0005975	carbohydrate metabolic process
0.40	GO:0007399	nervous system development
0.40	GO:0030154	cell differentiation
0.38	GO:0042391	regulation of membrane potential
0.37	GO:0006508	proteolysis
0.37	GO:0071805	potassium ion transmembrane transport
0.36	GO:0006886	intracellular protein transport
0.35	GO:0006950	response to stress

0.49	GO:0004930	G-protein coupled receptor activity
0.42	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.41	GO:0030248	cellulose binding
0.38	GO:0004175	endopeptidase activity
0.38	GO:0005249	voltage-gated potassium channel activity
0.37	GO:0005509	calcium ion binding
0.37	GO:0070001	aspartic-type peptidase activity
0.36	GO:0008237	metallopeptidase activity
0.36	GO:0008270	zinc ion binding

0.46	GO:0005576	extracellular region
0.38	GO:0031083	BLOC-1 complex
0.38	GO:0005887	integral component of plasma membrane

0.42

GO:0004553

tr|T1FS90|T1FS90_HELRO
Uncharacterized protein
Search

0.44	GO:0006468	protein phosphorylation
0.42	GO:2001141	regulation of RNA biosynthetic process
0.40	GO:0006351	transcription, DNA-templated
0.40	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.40	GO:0010468	regulation of gene expression
0.38	GO:0006379	mRNA cleavage
0.38	GO:0006378	mRNA polyadenylation
0.37	GO:0007018	microtubule-based movement
0.37	GO:0007064	mitotic sister chromatid cohesion
0.36	GO:0051254	positive regulation of RNA metabolic process

0.45	GO:0003676	nucleic acid binding
0.44	GO:0004672	protein kinase activity
0.42	GO:0005515	protein binding
0.42	GO:0140110	transcription regulator activity
0.41	GO:0030554	adenyl nucleotide binding
0.40	GO:0032555	purine ribonucleotide binding
0.40	GO:0008144	drug binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0008270	zinc ion binding
0.37	GO:0003777	microtubule motor activity

0.46	GO:0005634	nucleus
0.40	GO:0031974	membrane-enclosed lumen
0.38	GO:0031248	protein acetyltransferase complex
0.38	GO:0043234	protein complex
0.38	GO:1905368	peptidase complex
0.37	GO:0044446	intracellular organelle part
0.35	GO:0005856	cytoskeleton
0.33	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:2.7.7

GO:0016779

tr|T1FS91|T1FS91_HELRO
Uncharacterized protein
Search

SLC7A9

0.82	cystine/glutamate transporter

0.55	GO:0055085	transmembrane transport
0.50	GO:0006865	amino acid transport
0.42	GO:0072337	modified amino acid transport
0.41	GO:0072348	sulfur compound transport
0.40	GO:0070527	platelet aggregation
0.37	GO:0009636	response to toxic substance
0.35	GO:0006835	dicarboxylic acid transport
0.35	GO:0006836	neurotransmitter transport
0.34	GO:0015893	drug transport
0.34	GO:0050900	leukocyte migration

0.57	GO:0022857	transmembrane transporter activity
0.35	GO:0005326	neurotransmitter transporter activity
0.35	GO:0042605	peptide antigen binding
0.33	GO:0005515	protein binding
0.32	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.44	GO:0031526	brush border membrane
0.43	GO:0016324	apical plasma membrane
0.39	GO:0009986	cell surface
0.38	GO:0005887	integral component of plasma membrane

tr|T1FS92|T1FS92_HELRO
Uncharacterized protein
Search

tr|T1FS93|T1FS93_HELRO
Uncharacterized protein
Search

tr|T1FS94|T1FS94_HELRO
Uncharacterized protein
Search

0.24	Stress response protein nhaX

0.62

GO:0006950

response to stress

tr|T1FS95|T1FS95_HELRO
Uncharacterized protein
Search

0.72	GO:0006814	sodium ion transport
0.71	GO:0006813	potassium ion transport
0.66	GO:1903281	positive regulation of calcium:sodium antiporter activity
0.66	GO:1903288	positive regulation of potassium ion import
0.66	GO:1903275	positive regulation of sodium ion export
0.66	GO:1903276	regulation of sodium ion export across plasma membrane
0.65	GO:0055119	relaxation of cardiac muscle
0.64	GO:0006883	cellular sodium ion homeostasis
0.64	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling
0.64	GO:0086009	membrane repolarization

0.62	GO:0051117	ATPase binding
0.62	GO:0005391	sodium:potassium-exchanging ATPase activity
0.60	GO:0008022	protein C-terminus binding
0.59	GO:0001671	ATPase activator activity
0.59	GO:0031402	sodium ion binding
0.57	GO:0019901	protein kinase binding
0.57	GO:0030955	potassium ion binding
0.44	GO:0030554	adenyl nucleotide binding
0.44	GO:0008144	drug binding
0.44	GO:0097367	carbohydrate derivative binding

0.84	GO:0005890	sodium:potassium-exchanging ATPase complex
0.62	GO:0014704	intercalated disc
0.62	GO:0042383	sarcolemma
0.60	GO:0043209	myelin sheath
0.60	GO:0016323	basolateral plasma membrane
0.59	GO:0016324	apical plasma membrane
0.44	GO:0005901	caveola
0.39	GO:0005622	intracellular
0.39	GO:0070062	extracellular exosome

0.62

EC:3.6.3.9

GO:0005391

tr|T1FS96|T1FS96_HELRO
Uncharacterized protein
Search

0.47	GO:0006622	protein targeting to lysosome
0.44	GO:0016197	endosomal transport
0.42	GO:0007184	SMAD protein import into nucleus
0.42	GO:0007183	SMAD protein complex assembly
0.40	GO:0007179	transforming growth factor beta receptor signaling pathway
0.36	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway
0.35	GO:0072574	hepatocyte proliferation
0.34	GO:0030509	BMP signaling pathway
0.34	GO:0030100	regulation of endocytosis
0.34	GO:0016050	vesicle organization

0.53	GO:0046872	metal ion binding
0.48	GO:0005545	1-phosphatidylinositol binding
0.46	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.42	GO:0008565	protein transporter activity
0.39	GO:0019904	protein domain specific binding
0.36	GO:0046332	SMAD binding
0.32	GO:0008173	RNA methyltransferase activity
0.31	GO:0003723	RNA binding

0.47	GO:0005769	early endosome
0.43	GO:0005829	cytosol
0.40	GO:0010008	endosome membrane
0.39	GO:0043231	intracellular membrane-bounded organelle
0.36	GO:0043234	protein complex
0.33	GO:0070701	mucus layer
0.32	GO:0019867	outer membrane
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0008173

tr|T1FS97|T1FS97_HELRO
Uncharacterized protein
Search

tr|T1FS98|T1FS98_HELRO
Uncharacterized protein
Search

tr|T1FS99|T1FS99_HELRO
Uncharacterized protein
Search

0.58	GO:0034220	ion transmembrane transport
0.54	GO:0003008	system process
0.54	GO:0006812	cation transport
0.52	GO:0006979	response to oxidative stress
0.50	GO:0002724	regulation of T cell cytokine production
0.49	GO:0061337	cardiac conduction
0.48	GO:0035296	regulation of tube diameter
0.47	GO:0042391	regulation of membrane potential
0.44	GO:0071502	cellular response to temperature stimulus
0.44	GO:0071415	cellular response to purine-containing compound

0.67	GO:0005216	ion channel activity
0.60	GO:0047631	ADP-ribose diphosphatase activity
0.56	GO:0022836	gated channel activity
0.55	GO:0008324	cation transmembrane transporter activity
0.39	GO:0015318	inorganic molecular entity transmembrane transporter activity
0.39	GO:0043262	adenosine-diphosphatase activity
0.38	GO:0004871	signal transducer activity
0.34	GO:0019135	deoxyhypusine monooxygenase activity
0.34	GO:0004674	protein serine/threonine kinase activity
0.32	GO:0046872	metal ion binding

0.42	GO:0005765	lysosomal membrane
0.40	GO:0030659	cytoplasmic vesicle membrane
0.38	GO:0005887	integral component of plasma membrane
0.36	GO:0043025	neuronal cell body
0.36	GO:0043005	neuron projection
0.35	GO:0120038	plasma membrane bounded cell projection part
0.32	GO:0005739	mitochondrion

0.60

EC:3.6.1.13

GO:0047631

tr|T1FSA0|T1FSA0_HELRO
Uncharacterized protein
Search

tr|T1FSA1|T1FSA1_HELRO
Uncharacterized protein
Search

0.73

GO:0043213

bacteriocin transport

0.52

GO:0005215

transporter activity

0.54	GO:0005794	Golgi apparatus
0.30	GO:0016021	integral component of membrane

tr|T1FSA2|T1FSA2_HELRO
Uncharacterized protein
Search

0.42	Coagulation factor IX

0.61	GO:0006508	proteolysis
0.38	GO:0006898	receptor-mediated endocytosis
0.36	GO:0050878	regulation of body fluid levels
0.36	GO:0050817	coagulation
0.36	GO:0042060	wound healing
0.35	GO:0022617	extracellular matrix disassembly
0.35	GO:0050819	negative regulation of coagulation
0.35	GO:0061045	negative regulation of wound healing
0.35	GO:0006030	chitin metabolic process
0.34	GO:0006952	defense response

0.69	GO:0004252	serine-type endopeptidase activity
0.39	GO:0005044	scavenger receptor activity
0.36	GO:0005509	calcium ion binding
0.35	GO:0008201	heparin binding
0.35	GO:0008061	chitin binding
0.34	GO:0005515	protein binding

0.40	GO:0005576	extracellular region
0.35	GO:0042629	mast cell granule
0.34	GO:0043025	neuronal cell body
0.33	GO:0046658	anchored component of plasma membrane
0.33	GO:0019897	extrinsic component of plasma membrane
0.32	GO:0030141	secretory granule
0.30	GO:0016021	integral component of membrane

0.69

GO:0004252

tr|T1FSA3|T1FSA3_HELRO
Uncharacterized protein
Search

tr|T1FSA4|T1FSA4_HELRO
Uncharacterized protein
Search

CPNE3

0.84	Copine III

0.85	GO:0071277	cellular response to calcium ion
0.66	GO:0038128	ERBB2 signaling pathway
0.59	GO:0030335	positive regulation of cell migration
0.58	GO:0071363	cellular response to growth factor stimulus
0.49	GO:0006468	protein phosphorylation
0.39	GO:0043312	neutrophil degranulation
0.36	GO:0046474	glycerophospholipid biosynthetic process

0.62	GO:0048306	calcium-dependent protein binding
0.61	GO:0030971	receptor tyrosine kinase binding
0.59	GO:0005544	calcium-dependent phospholipid binding
0.53	GO:0004674	protein serine/threonine kinase activity
0.37	GO:0003723	RNA binding
0.34	GO:0005215	transporter activity

0.61	GO:0005634	nucleus
0.59	GO:0005925	focal adhesion
0.55	GO:0005886	plasma membrane
0.52	GO:0005829	cytosol
0.52	GO:0031974	membrane-enclosed lumen
0.48	GO:0005739	mitochondrion
0.47	GO:0043232	intracellular non-membrane-bounded organelle
0.46	GO:0044446	intracellular organelle part
0.46	GO:0070062	extracellular exosome
0.43	GO:0045334	clathrin-coated endocytic vesicle

0.53

GO:0004674

tr|T1FSA5|T1FSA5_HELRO
Uncharacterized protein
Search

FBXO8

0.92	F-box only protein 8

0.81	GO:0032012	regulation of ARF protein signal transduction
0.66	GO:0065009	regulation of molecular function
0.48	GO:0006511	ubiquitin-dependent protein catabolic process

0.82

GO:0005086

ARF guanyl-nucleotide exchange factor activity

0.49	GO:0000151	ubiquitin ligase complex
0.30	GO:0031224	intrinsic component of membrane

tr|T1FSA6|T1FSA6_HELRO
Uncharacterized protein
Search

tr|T1FSA7|T1FSA7_HELRO
Uncharacterized protein
Search

0.10	CRAL-TRIO domain-containing protein C23B6.04c

0.63

GO:0045454

cell redox homeostasis

0.54

GO:0000062

fatty-acyl-CoA binding

0.30	GO:0044425	membrane part
0.30	GO:0005623	cell

tr|T1FSA8|T1FSA8_HELRO
Uncharacterized protein
Search

0.46	GO:0098656	anion transmembrane transport
0.45	GO:0015698	inorganic anion transport
0.43	GO:0045596	negative regulation of cell differentiation
0.43	GO:0051241	negative regulation of multicellular organismal process
0.42	GO:0048666	neuron development
0.42	GO:0030516	regulation of axon extension
0.42	GO:0048640	negative regulation of developmental growth
0.42	GO:0030308	negative regulation of cell growth
0.42	GO:0018108	peptidyl-tyrosine phosphorylation
0.41	GO:0031345	negative regulation of cell projection organization

0.51	GO:0005452	inorganic anion exchanger activity
0.43	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.41	GO:0005515	protein binding
0.40	GO:0140110	transcription regulator activity
0.39	GO:0003676	nucleic acid binding
0.39	GO:0044877	macromolecular complex binding
0.39	GO:0008510	sodium:bicarbonate symporter activity
0.38	GO:0008270	zinc ion binding
0.37	GO:0030554	adenyl nucleotide binding
0.37	GO:0097367	carbohydrate derivative binding

0.43	GO:0005634	nucleus
0.38	GO:0030014	CCR4-NOT complex
0.37	GO:0031248	protein acetyltransferase complex
0.37	GO:0000428	DNA-directed RNA polymerase complex
0.37	GO:0005667	transcription factor complex
0.36	GO:1905368	peptidase complex
0.35	GO:0070013	intracellular organelle lumen
0.35	GO:0005887	integral component of plasma membrane
0.35	GO:0005737	cytoplasm
0.34	GO:0044446	intracellular organelle part

0.43

EC:2.7.10.2

GO:0004715

tr|T1FSA9|T1FSA9_HELRO
Uncharacterized protein
Search

0.42	GO:0016071	mRNA metabolic process
0.42	GO:0006396	RNA processing
0.41	GO:0022613	ribonucleoprotein complex biogenesis
0.41	GO:0046907	intracellular transport
0.40	GO:0016567	protein ubiquitination
0.40	GO:0070727	cellular macromolecule localization
0.39	GO:0016192	vesicle-mediated transport
0.39	GO:0031323	regulation of cellular metabolic process
0.39	GO:0051171	regulation of nitrogen compound metabolic process
0.39	GO:0060255	regulation of macromolecule metabolic process

0.43	GO:0003676	nucleic acid binding
0.40	GO:0004842	ubiquitin-protein transferase activity
0.40	GO:0008270	zinc ion binding
0.39	GO:0042802	identical protein binding
0.38	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting
0.38	GO:0004864	protein phosphatase inhibitor activity
0.38	GO:0005487	structural constituent of nuclear pore
0.38	GO:0004633	phosphopantothenoylcysteine decarboxylase activity
0.38	GO:0004386	helicase activity
0.37	GO:0030276	clathrin binding

0.52	GO:0005634	nucleus
0.42	GO:0043234	protein complex
0.41	GO:0030684	preribosome
0.41	GO:0044446	intracellular organelle part
0.40	GO:0071513	phosphopantothenoylcysteine decarboxylase complex
0.39	GO:0043232	intracellular non-membrane-bounded organelle
0.38	GO:0097014	ciliary plasm
0.38	GO:0012505	endomembrane system
0.37	GO:0070013	intracellular organelle lumen
0.37	GO:0048475	coated membrane

0.38	EC:4.1.1.36	GO:0004633
0.40	KEGG:R03876	GO:0004842

tr|T1FSB0|T1FSB0_HELRO
Uncharacterized protein
Search

0.54	GO:0006364	rRNA processing
0.44	GO:0080111	DNA demethylation
0.40	GO:0006413	translational initiation
0.40	GO:0006904	vesicle docking involved in exocytosis
0.39	GO:0030097	hemopoiesis
0.37	GO:0006631	fatty acid metabolic process
0.36	GO:0006468	protein phosphorylation
0.35	GO:0055114	oxidation-reduction process

0.43	GO:0004386	helicase activity
0.42	GO:0032555	purine ribonucleotide binding
0.42	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0003676	nucleic acid binding
0.41	GO:0032550	purine ribonucleoside binding
0.41	GO:0019001	guanyl nucleotide binding
0.40	GO:0030554	adenyl nucleotide binding
0.40	GO:0045300	acyl-[acyl-carrier-protein] desaturase activity
0.40	GO:0008144	drug binding
0.39	GO:0003924	GTPase activity

0.57	GO:0032040	small-subunit processome
0.42	GO:0005634	nucleus
0.39	GO:0031974	membrane-enclosed lumen
0.37	GO:0019013	viral nucleocapsid
0.37	GO:0043232	intracellular non-membrane-bounded organelle
0.37	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.40

EC:1.14.19.2

GO:0045300

tr|T1FSB1|T1FSB1_HELRO
Uncharacterized protein
Search

0.42	GO:0007412	axon target recognition
0.42	GO:0045570	regulation of imaginal disc growth
0.42	GO:0008345	larval locomotory behavior
0.42	GO:0048190	wing disc dorsal/ventral pattern formation
0.42	GO:0045879	negative regulation of smoothened signaling pathway
0.41	GO:0007476	imaginal disc-derived wing morphogenesis
0.40	GO:0007411	axon guidance
0.40	GO:0000122	negative regulation of transcription by RNA polymerase II
0.34	GO:0051568	histone H3-K4 methylation
0.33	GO:0006413	translational initiation

0.51	GO:0003676	nucleic acid binding
0.40	GO:0003714	transcription corepressor activity
0.34	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.32	GO:0046872	metal ion binding

0.37	GO:0005634	nucleus
0.34	GO:0034708	methyltransferase complex
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

tr|T1FSB2|T1FSB2_HELRO
Uncharacterized protein
Search

tr|T1FSB3|T1FSB3_HELRO
Uncharacterized protein
Search

tr|T1FSB4|T1FSB4_HELRO
Uncharacterized protein
Search

tr|T1FSB5|T1FSB5_HELRO
Uncharacterized protein
Search

tr|T1FSB6|T1FSB6_HELRO
Uncharacterized protein
Search

0.61	GO:0007399	nervous system development
0.58	GO:0007155	cell adhesion
0.49	GO:0048704	embryonic skeletal system morphogenesis
0.47	GO:0060322	head development
0.41	GO:0030334	regulation of cell migration
0.41	GO:0051960	regulation of nervous system development
0.41	GO:0060284	regulation of cell development
0.40	GO:0030154	cell differentiation
0.35	GO:0009888	tissue development
0.35	GO:0048589	developmental growth

0.46	GO:0042803	protein homodimerization activity
0.36	GO:0005509	calcium ion binding
0.36	GO:0005216	ion channel activity
0.34	GO:0004725	protein tyrosine phosphatase activity
0.33	GO:0004713	protein tyrosine kinase activity
0.33	GO:0046982	protein heterodimerization activity
0.33	GO:0031433	telethonin binding
0.33	GO:0097493	structural molecule activity conferring elasticity
0.33	GO:0051371	muscle alpha-actinin binding
0.33	GO:1904929	coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway

0.46	GO:0009986	cell surface
0.40	GO:0005887	integral component of plasma membrane
0.40	GO:0005576	extracellular region
0.35	GO:0005938	cell cortex
0.34	GO:0030054	cell junction
0.33	GO:0005859	muscle myosin complex
0.33	GO:0046695	SLIK (SAGA-like) complex
0.33	GO:0031430	M band
0.33	GO:0000124	SAGA complex
0.33	GO:0030018	Z disc

0.34

GO:0004725

tr|T1FSB7|T1FSB7_HELRO
Uncharacterized protein
Search

0.73	GO:0010457	centriole-centriole cohesion
0.71	GO:0007099	centriole replication
0.62	GO:0007283	spermatogenesis
0.43	GO:0030031	cell projection assembly
0.34	GO:0090162	establishment of epithelial cell polarity
0.34	GO:0006629	lipid metabolic process
0.34	GO:0044782	cilium organization
0.33	GO:0016567	protein ubiquitination

0.41	GO:0070840	dynein complex binding
0.39	GO:0042803	protein homodimerization activity
0.38	GO:0008134	transcription factor binding
0.34	GO:0005198	structural molecule activity
0.33	GO:0004806	triglyceride lipase activity
0.33	GO:0004842	ubiquitin-protein transferase activity
0.32	GO:0016874	ligase activity
0.32	GO:0008270	zinc ion binding

0.45	GO:0031514	motile cilium
0.44	GO:0043005	neuron projection
0.36	GO:0005814	centriole
0.36	GO:0031965	nuclear membrane
0.34	GO:0097539	ciliary transition fiber
0.30	GO:0031224	intrinsic component of membrane

0.33	EC:3.1.1.3	GO:0004806
0.33	KEGG:R03876	GO:0004842

tr|T1FSB8|T1FSB8_HELRO
Uncharacterized protein
Search

0.51	GO:0005987	sucrose catabolic process
0.51	GO:2000219	positive regulation of invasive growth in response to glucose limitation
0.50	GO:0045944	positive regulation of transcription by RNA polymerase II
0.50	GO:0045991	carbon catabolite activation of transcription
0.49	GO:0000429	carbon catabolite regulation of transcription from RNA polymerase II promoter
0.47	GO:1901407	regulation of phosphorylation of RNA polymerase II C-terminal domain
0.47	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle
0.47	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle
0.46	GO:0006338	chromatin remodeling
0.46	GO:0000724	double-strand break repair via homologous recombination

0.55	GO:0003726	double-stranded RNA adenosine deaminase activity
0.50	GO:0015616	DNA translocase activity
0.49	GO:0001102	RNA polymerase II activating transcription factor binding
0.47	GO:0005199	structural constituent of cell wall
0.47	GO:0000993	RNA polymerase II core binding
0.47	GO:0002039	p53 binding
0.46	GO:0140033	acetylation-dependent protein binding
0.45	GO:0042393	histone binding
0.44	GO:0042302	structural constituent of cuticle
0.44	GO:0003682	chromatin binding

0.50	GO:0000228	nuclear chromosome
0.47	GO:0005829	cytosol
0.44	GO:0000785	chromatin
0.44	GO:0000793	condensed chromosome
0.42	GO:1904949	ATPase complex
0.42	GO:0005654	nucleoplasm
0.37	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1FSB9|T1FSB9_HELRO
Uncharacterized protein
Search

0.49

GO:0003676

nucleic acid binding

0.30

GO:0044425

membrane part

tr|T1FSC0|T1FSC0_HELRO
Uncharacterized protein
Search

tr|T1FSC1|T1FSC1_HELRO
Uncharacterized protein
Search

tr|T1FSC2|T1FSC2_HELRO
Uncharacterized protein
Search

0.46	GO:0061412	positive regulation of transcription from RNA polymerase II promoter in response to amino acid starvation
0.46	GO:0044109	cellular alcohol catabolic process
0.46	GO:0031496	positive regulation of mating type switching
0.46	GO:0005987	sucrose catabolic process
0.46	GO:0051983	regulation of chromosome segregation
0.45	GO:0000436	carbon catabolite activation of transcription from RNA polymerase II promoter
0.45	GO:0008608	attachment of spindle microtubules to kinetochore
0.44	GO:0051276	chromosome organization
0.43	GO:0140014	mitotic nuclear division
0.42	GO:0007088	regulation of mitotic nuclear division

0.54	GO:0050290	sphingomyelin phosphodiesterase D activity
0.45	GO:0015616	DNA translocase activity
0.44	GO:0001102	RNA polymerase II activating transcription factor binding
0.40	GO:0043130	ubiquitin binding
0.40	GO:0003677	DNA binding
0.38	GO:0035312	5'-3' exodeoxyribonuclease activity
0.38	GO:0003729	mRNA binding
0.38	GO:0004930	G-protein coupled receptor activity
0.37	GO:0046872	metal ion binding
0.35	GO:0003700	DNA binding transcription factor activity

0.46	GO:0005634	nucleus
0.45	GO:0044427	chromosomal part
0.42	GO:1990298	bub1-bub3 complex
0.40	GO:0070013	intracellular organelle lumen
0.40	GO:1902494	catalytic complex
0.39	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.39	GO:0031252	cell leading edge
0.39	GO:0030173	integral component of Golgi membrane
0.38	GO:0032300	mismatch repair complex
0.38	GO:0030134	COPII-coated ER to Golgi transport vesicle

0.54	EC:3.1.4.41	GO:0050290
0.54	KEGG:R02542	GO:0050290

tr|T1FSC3|T1FSC3_HELRO
Uncharacterized protein
Search

tr|T1FSC4|T1FSC4_HELRO
Uncharacterized protein
Search

tr|T1FSC5|T1FSC5_HELRO
Uncharacterized protein
Search

tr|T1FSC6|T1FSC6_HELRO
Uncharacterized protein
Search

0.71	GO:0007009	plasma membrane organization
0.41	GO:0006886	intracellular protein transport
0.40	GO:0006888	ER to Golgi vesicle-mediated transport
0.39	GO:0048106	establishment of thoracic bristle planar orientation
0.39	GO:0035321	maintenance of imaginal disc-derived wing hair orientation
0.39	GO:0031153	slug development involved in sorocarp development
0.39	GO:0036211	protein modification process
0.39	GO:0007403	glial cell fate determination
0.38	GO:0060255	regulation of macromolecule metabolic process
0.38	GO:0007400	neuroblast fate determination

0.64	GO:0003779	actin binding
0.40	GO:0042162	telomeric DNA binding
0.39	GO:0003727	single-stranded RNA binding
0.39	GO:0046872	metal ion binding
0.38	GO:0042803	protein homodimerization activity
0.38	GO:0033204	ribonuclease P RNA binding
0.37	GO:0004674	protein serine/threonine kinase activity
0.37	GO:0031625	ubiquitin protein ligase binding
0.36	GO:0008097	5S rRNA binding
0.36	GO:0003682	chromatin binding

0.41	GO:0044433	cytoplasmic vesicle part
0.40	GO:0098805	whole membrane
0.40	GO:0030134	COPII-coated ER to Golgi transport vesicle
0.40	GO:0098588	bounding membrane of organelle
0.40	GO:0030133	transport vesicle
0.40	GO:0012506	vesicle membrane
0.39	GO:0030117	membrane coat
0.38	GO:0016035	zeta DNA polymerase complex
0.37	GO:0005634	nucleus
0.37	GO:0019005	SCF ubiquitin ligase complex

0.37	EC:2.7.11	GO:0004674
0.36	KEGG:R03876	GO:0004842

tr|T1FSC7|T1FSC7_HELRO
Uncharacterized protein
Search

0.40	GO:0016192	vesicle-mediated transport
0.40	GO:0031323	regulation of cellular metabolic process
0.40	GO:0051171	regulation of nitrogen compound metabolic process
0.40	GO:0060255	regulation of macromolecule metabolic process
0.40	GO:0080090	regulation of primary metabolic process
0.40	GO:0009889	regulation of biosynthetic process
0.39	GO:0007015	actin filament organization
0.38	GO:0098657	import into cell
0.38	GO:0015031	protein transport
0.37	GO:0032446	protein modification by small protein conjugation

0.62	GO:0045735	nutrient reservoir activity
0.42	GO:0042393	histone binding
0.40	GO:0043130	ubiquitin binding
0.40	GO:0030674	protein binding, bridging
0.39	GO:0008092	cytoskeletal protein binding
0.39	GO:0003712	transcription cofactor activity
0.39	GO:0003723	RNA binding
0.39	GO:0017020	myosin phosphatase regulator activity
0.38	GO:0042802	identical protein binding
0.38	GO:0050825	ice binding

0.42	GO:0005634	nucleus
0.39	GO:0019867	outer membrane
0.39	GO:0044433	cytoplasmic vesicle part
0.39	GO:0012505	endomembrane system
0.39	GO:0044462	external encapsulating structure part
0.38	GO:0030117	membrane coat
0.38	GO:0098805	whole membrane
0.38	GO:0030313	cell envelope
0.38	GO:0098588	bounding membrane of organelle
0.38	GO:0044430	cytoskeletal part

0.37	EC:2.7.1	GO:0016538
0.36	KEGG:R03876	GO:0004842

tr|T1FSC8|T1FSC8_HELRO
Uncharacterized protein
Search

tr|T1FSC9|T1FSC9_HELRO
Uncharacterized protein
Search

tr|T1FSD0|T1FSD0_HELRO
Uncharacterized protein
Search

0.44	GO:0060255	regulation of macromolecule metabolic process
0.43	GO:0031326	regulation of cellular biosynthetic process
0.43	GO:0051171	regulation of nitrogen compound metabolic process
0.43	GO:0080090	regulation of primary metabolic process
0.41	GO:0006468	protein phosphorylation
0.40	GO:0048518	positive regulation of biological process
0.40	GO:0044093	positive regulation of molecular function
0.39	GO:0016071	mRNA metabolic process
0.39	GO:0009892	negative regulation of metabolic process
0.39	GO:0006401	RNA catabolic process

0.45	GO:0050825	ice binding
0.44	GO:0045735	nutrient reservoir activity
0.43	GO:0008270	zinc ion binding
0.42	GO:0003676	nucleic acid binding
0.41	GO:0016301	kinase activity
0.41	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.41	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.40	GO:0140096	catalytic activity, acting on a protein
0.39	GO:0030554	adenyl nucleotide binding
0.38	GO:0097367	carbohydrate derivative binding

0.46	GO:0005634	nucleus
0.38	GO:0032991	macromolecular complex
0.36	GO:0070013	intracellular organelle lumen
0.36	GO:0005737	cytoplasm
0.35	GO:0044459	plasma membrane part
0.35	GO:0097708	intracellular vesicle
0.35	GO:0044446	intracellular organelle part
0.34	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.41

GO:0016773

tr|T1FSD1|T1FSD1_HELRO
Uncharacterized protein
Search

tr|T1FSD2|T1FSD2_HELRO
Uncharacterized protein
Search

0.57	GO:0007229	integrin-mediated signaling pathway
0.50	GO:0000272	polysaccharide catabolic process
0.48	GO:0006508	proteolysis
0.43	GO:0006030	chitin metabolic process
0.37	GO:0045491	xylan metabolic process
0.37	GO:0018996	molting cycle, collagen and cuticulin-based cuticle
0.37	GO:0032392	DNA geometric change
0.36	GO:0007155	cell adhesion
0.35	GO:0030243	cellulose metabolic process
0.35	GO:0044275	cellular carbohydrate catabolic process

0.53	GO:0004222	metalloendopeptidase activity
0.45	GO:0008061	chitin binding
0.44	GO:0046872	metal ion binding
0.42	GO:0030248	cellulose binding
0.41	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.38	GO:0004003	ATP-dependent DNA helicase activity
0.36	GO:0004252	serine-type endopeptidase activity
0.36	GO:0030570	pectate lyase activity
0.35	GO:0003682	chromatin binding
0.35	GO:0004930	G-protein coupled receptor activity

0.48	GO:0005576	extracellular region
0.37	GO:0005765	lysosomal membrane
0.36	GO:0005634	nucleus
0.36	GO:0005618	cell wall
0.30	GO:0031224	intrinsic component of membrane

0.53

GO:0004222

tr|T1FSD3|T1FSD3_HELRO
FK506-binding protein
Search

0.15	Peptidylprolyl isomerase

0.71	GO:0000413	protein peptidyl-prolyl isomerization
0.54	GO:0006457	protein folding
0.51	GO:0016570	histone modification
0.33	GO:0031498	chromatin disassembly
0.33	GO:0032986	protein-DNA complex disassembly
0.33	GO:0044265	cellular macromolecule catabolic process
0.33	GO:0090304	nucleic acid metabolic process
0.33	GO:0006334	nucleosome assembly
0.33	GO:0018393	internal peptidyl-lysine acetylation
0.32	GO:0034655	nucleobase-containing compound catabolic process

0.71	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.57	GO:0005528	FK506 binding
0.33	GO:0003684	damaged DNA binding
0.33	GO:0042393	histone binding
0.32	GO:0003682	chromatin binding
0.32	GO:0004674	protein serine/threonine kinase activity
0.32	GO:0042802	identical protein binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.31	GO:0016787	hydrolase activity

0.50	GO:0005730	nucleolus
0.33	GO:0032299	ribonuclease H2 complex
0.33	GO:0044732	mitotic spindle pole body
0.32	GO:0000784	nuclear chromosome, telomeric region
0.32	GO:0034399	nuclear periphery
0.32	GO:0030687	preribosome, large subunit precursor
0.30	GO:0031224	intrinsic component of membrane

0.71

EC:5.2.1.8

GO:0003755

tr|T1FSD4|T1FSD4_HELRO
Uncharacterized protein
Search

0.59	GO:0007601	visual perception
0.46	GO:0050896	response to stimulus

0.30

GO:0016021

integral component of membrane

tr|T1FSD5|T1FSD5_HELRO
Uncharacterized protein
Search

tr|T1FSD6|T1FSD6_HELRO
Uncharacterized protein
Search

0.78	GO:0035023	regulation of Rho protein signal transduction
0.67	GO:0022011	myelination in peripheral nervous system
0.66	GO:0065009	regulation of molecular function
0.65	GO:0090307	mitotic spindle assembly
0.46	GO:0051496	positive regulation of stress fiber assembly
0.44	GO:0051298	centrosome duplication
0.36	GO:0032933	SREBP signaling pathway
0.35	GO:0048015	phosphatidylinositol-mediated signaling
0.34	GO:0046854	phosphatidylinositol phosphorylation
0.33	GO:0006816	calcium ion transport

0.78	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.44	GO:0019894	kinesin binding
0.35	GO:0005096	GTPase activator activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0004430	1-phosphatidylinositol 4-kinase activity
0.33	GO:0005216	ion channel activity
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0046872	metal ion binding

0.61	GO:0005813	centrosome
0.55	GO:0005829	cytosol
0.32	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.33	EC:2.7.1.67	GO:0004430
0.33	KEGG:R03361	GO:0004430

tr|T1FSD7|T1FSD7_HELRO
Uncharacterized protein
Search

0.54	GO:0016310	phosphorylation
0.42	GO:0000398	mRNA splicing, via spliceosome
0.38	GO:0000470	maturation of LSU-rRNA
0.38	GO:0000460	maturation of 5.8S rRNA
0.37	GO:0007076	mitotic chromosome condensation
0.36	GO:0006270	DNA replication initiation
0.36	GO:0036211	protein modification process
0.36	GO:0032392	DNA geometric change
0.35	GO:0051301	cell division
0.35	GO:0044267	cellular protein metabolic process

0.57	GO:0016301	kinase activity
0.36	GO:0004842	ubiquitin-protein transferase activity
0.36	GO:0003678	DNA helicase activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.35	GO:0003723	RNA binding
0.34	GO:0016874	ligase activity
0.34	GO:0003677	DNA binding

0.45	GO:0000974	Prp19 complex
0.42	GO:0005681	spliceosomal complex
0.38	GO:0030687	preribosome, large subunit precursor
0.37	GO:0042555	MCM complex
0.37	GO:0005730	nucleolus
0.30	GO:0016020	membrane

0.35	EC:2.7.1	GO:0016773
0.36	KEGG:R03876	GO:0004842

tr|T1FSD8|T1FSD8_HELRO
Uncharacterized protein
Search

0.41	GO:0036211	protein modification process
0.41	GO:0006030	chitin metabolic process
0.40	GO:0044267	cellular protein metabolic process
0.38	GO:0016569	covalent chromatin modification
0.37	GO:0016070	RNA metabolic process
0.37	GO:0010467	gene expression
0.37	GO:0016310	phosphorylation
0.37	GO:0043414	macromolecule methylation
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.41	GO:0008061	chitin binding
0.40	GO:0140096	catalytic activity, acting on a protein
0.39	GO:0016874	ligase activity
0.39	GO:0016740	transferase activity
0.38	GO:0003676	nucleic acid binding
0.37	GO:0046872	metal ion binding
0.37	GO:0032555	purine ribonucleotide binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0030246	carbohydrate binding
0.37	GO:0003924	GTPase activity

0.39	GO:0005634	nucleus
0.38	GO:0005576	extracellular region
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.39

GO:0016874

tr|T1FSD9|T1FSD9_HELRO
Uncharacterized protein
Search

0.63	GO:0035023	regulation of Rho protein signal transduction
0.55	GO:0065009	regulation of molecular function
0.50	GO:0035556	intracellular signal transduction
0.46	GO:0051897	positive regulation of protein kinase B signaling
0.45	GO:0043524	negative regulation of neuron apoptotic process
0.43	GO:0042327	positive regulation of phosphorylation
0.41	GO:0006897	endocytosis
0.37	GO:0007010	cytoskeleton organization
0.37	GO:0007017	microtubule-based process
0.36	GO:0006629	lipid metabolic process

0.65	GO:0005509	calcium ion binding
0.64	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.47	GO:0070064	proline-rich region binding
0.45	GO:0019209	kinase activator activity
0.45	GO:0032947	protein complex scaffold activity
0.35	GO:0004806	triglyceride lipase activity
0.35	GO:0003777	microtubule motor activity
0.35	GO:0019789	SUMO transferase activity
0.35	GO:0008017	microtubule binding
0.34	GO:0019905	syntaxin binding

0.45	GO:0030027	lamellipodium
0.45	GO:0030139	endocytic vesicle
0.44	GO:0005905	clathrin-coated pit
0.37	GO:0071944	cell periphery
0.36	GO:0005856	cytoskeleton
0.35	GO:0000938	GARP complex
0.34	GO:0005829	cytosol
0.34	GO:0099568	cytoplasmic region
0.33	GO:0032040	small-subunit processome
0.33	GO:0005634	nucleus

0.35

EC:3.1.1.3

GO:0004806

tr|T1FSE0|T1FSE0_HELRO
Uncharacterized protein
Search

tr|T1FSE1|T1FSE1_HELRO
Uncharacterized protein
Search

0.42	GO:0051014	actin filament severing
0.40	GO:0030036	actin cytoskeleton organization
0.39	GO:0006468	protein phosphorylation
0.39	GO:0006952	defense response
0.38	GO:0043331	response to dsRNA
0.38	GO:0002224	toll-like receptor signaling pathway
0.37	GO:0009615	response to virus
0.37	GO:0002252	immune effector process

0.41	GO:0051015	actin filament binding
0.39	GO:0004672	protein kinase activity
0.38	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0043168	anion binding
0.37	GO:0003725	double-stranded RNA binding
0.37	GO:0008144	drug binding
0.35	GO:0004872	receptor activity

0.36

GO:0005887

integral component of plasma membrane

tr|T1FSE2|T1FSE2_HELRO
Uncharacterized protein
Search

0.68	GO:0006886	intracellular protein transport
0.47	GO:0006606	protein import into nucleus

0.78	GO:0008536	Ran GTPase binding
0.44	GO:0008565	protein transporter activity

0.58	GO:0005634	nucleus
0.40	GO:0031974	membrane-enclosed lumen
0.39	GO:0044446	intracellular organelle part
0.39	GO:0005829	cytosol
0.39	GO:0012505	endomembrane system
0.38	GO:0043232	intracellular non-membrane-bounded organelle
0.37	GO:0031975	envelope

tr|T1FSE3|T1FSE3_HELRO
Uncharacterized protein
Search

tr|T1FSE4|T1FSE4_HELRO
Uncharacterized protein
Search

0.57	GO:0007165	signal transduction
0.39	GO:0051568	histone H3-K4 methylation
0.38	GO:0046854	phosphatidylinositol phosphorylation
0.37	GO:0009966	regulation of signal transduction
0.36	GO:0016477	cell migration
0.35	GO:0051173	positive regulation of nitrogen compound metabolic process
0.35	GO:0010604	positive regulation of macromolecule metabolic process
0.35	GO:0080090	regulation of primary metabolic process
0.35	GO:0031323	regulation of cellular metabolic process
0.35	GO:0043627	response to estrogen

0.66	GO:0008289	lipid binding
0.40	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.37	GO:0017048	Rho GTPase binding
0.36	GO:0004430	1-phosphatidylinositol 4-kinase activity
0.35	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.35	GO:0046872	metal ion binding
0.35	GO:0070325	lipoprotein particle receptor binding
0.35	GO:0003721	telomerase RNA reverse transcriptase activity
0.34	GO:0044212	transcription regulatory region DNA binding
0.34	GO:0046982	protein heterodimerization activity

0.39	GO:0035097	histone methyltransferase complex
0.35	GO:0030906	retromer, cargo-selective complex
0.34	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.36	EC:2.7.1.67	GO:0004430
0.36	KEGG:R03361	GO:0004430

tr|T1FSE5|T1FSE5_HELRO
Uncharacterized protein
Search

0.38	GO:0018108	peptidyl-tyrosine phosphorylation
0.36	GO:0032012	regulation of ARF protein signal transduction
0.36	GO:0006359	regulation of transcription by RNA polymerase III
0.35	GO:0007093	mitotic cell cycle checkpoint
0.35	GO:0051304	chromosome separation
0.35	GO:0006383	transcription by RNA polymerase III
0.35	GO:0016575	histone deacetylation
0.34	GO:0065009	regulation of molecular function
0.34	GO:0007165	signal transduction

0.62	GO:0008270	zinc ion binding
0.50	GO:0003676	nucleic acid binding
0.39	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.36	GO:0001026	TFIIIB-type transcription factor activity
0.36	GO:0005086	ARF guanyl-nucleotide exchange factor activity
0.36	GO:0004712	protein serine/threonine/tyrosine kinase activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0003700	DNA binding transcription factor activity

0.36	GO:0000126	transcription factor TFIIIB complex
0.30	GO:0016020	membrane

0.39

EC:2.7.10.2

GO:0004715

tr|T1FSE6|T1FSE6_HELRO
Uncharacterized protein
Search

0.84	GO:0090204	protein localization to nuclear pore
0.83	GO:0046833	positive regulation of RNA export from nucleus
0.82	GO:0046826	negative regulation of protein export from nucleus
0.75	GO:0006606	protein import into nucleus
0.53	GO:0051028	mRNA transport
0.52	GO:0006405	RNA export from nucleus
0.51	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.47	GO:0006611	protein export from nucleus
0.47	GO:0000056	ribosomal small subunit export from nucleus
0.46	GO:0000055	ribosomal large subunit export from nucleus

0.55	GO:0005487	structural constituent of nuclear pore
0.51	GO:0004776	succinate-CoA ligase (GDP-forming) activity
0.47	GO:0005049	nuclear export signal receptor activity
0.47	GO:0004775	succinate-CoA ligase (ADP-forming) activity
0.45	GO:0008139	nuclear localization sequence binding
0.43	GO:0032296	double-stranded RNA-specific ribonuclease activity
0.41	GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters
0.39	GO:0048037	cofactor binding
0.39	GO:0005515	protein binding
0.38	GO:1901265	nucleoside phosphate binding

0.75	GO:0005643	nuclear pore
0.45	GO:0005925	focal adhesion
0.41	GO:0005739	mitochondrion

0.51	EC:6.2.1.4	GO:0004776
0.51	KEGG:R00432	GO:0004776

tr|T1FSE7|T1FSE7_HELRO
Uncharacterized protein
Search

0.67	GO:0071897	DNA biosynthetic process
0.66	GO:0006260	DNA replication
0.65	GO:0006281	DNA repair
0.60	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.43	GO:0022616	DNA strand elongation
0.42	GO:0000278	mitotic cell cycle
0.39	GO:0044843	cell cycle G1/S phase transition
0.37	GO:0016070	RNA metabolic process

0.71	GO:0003887	DNA-directed DNA polymerase activity
0.68	GO:0008408	3'-5' exonuclease activity
0.62	GO:0008270	zinc ion binding
0.55	GO:0003677	DNA binding
0.53	GO:1901265	nucleoside phosphate binding
0.51	GO:0036094	small molecule binding
0.44	GO:0008297	single-stranded DNA exodeoxyribonuclease activity
0.38	GO:0003682	chromatin binding

0.84	GO:0008622	epsilon DNA polymerase complex
0.37	GO:0005654	nucleoplasm
0.35	GO:0005886	plasma membrane

0.71

GO:0003887

tr|T1FSE8|T1FSE8_HELRO
Uncharacterized protein
Search

tr|T1FSE9|T1FSE9_HELRO
Uncharacterized protein
Search

0.51	GO:0032233	positive regulation of actin filament bundle assembly
0.42	GO:0007275	multicellular organism development
0.39	GO:0014706	striated muscle tissue development
0.38	GO:0061061	muscle structure development
0.38	GO:2001141	regulation of RNA biosynthetic process
0.38	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.38	GO:0010468	regulation of gene expression
0.36	GO:0006468	protein phosphorylation
0.35	GO:0006351	transcription, DNA-templated

0.47	GO:0003779	actin binding
0.46	GO:0005198	structural molecule activity
0.39	GO:0003700	DNA binding transcription factor activity
0.39	GO:0046872	metal ion binding
0.39	GO:0003676	nucleic acid binding
0.39	GO:0051087	chaperone binding
0.37	GO:0004674	protein serine/threonine kinase activity
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0008144	drug binding

0.61	GO:0016607	nuclear speck
0.58	GO:0030054	cell junction
0.54	GO:0005829	cytosol
0.51	GO:0030018	Z disc
0.47	GO:0015629	actin cytoskeleton

0.37

GO:0004674

tr|T1FSF0|T1FSF0_HELRO
Uncharacterized protein
Search

0.34

GO:0003723

RNA binding

0.69

GO:0005856

cytoskeleton

tr|T1FSF1|T1FSF1_HELRO
Uncharacterized protein
Search

MSH2

0.58	DNA mismatch repair protein msh-2

0.75	GO:0006298	mismatch repair
0.52	GO:0016446	somatic hypermutation of immunoglobulin genes
0.51	GO:0043570	maintenance of DNA repeat elements
0.51	GO:0002204	somatic recombination of immunoglobulin genes involved in immune response
0.51	GO:0006311	meiotic gene conversion
0.51	GO:0006301	postreplication repair
0.51	GO:0010165	response to X-ray
0.51	GO:0051053	negative regulation of DNA metabolic process
0.51	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
0.50	GO:0002312	B cell activation involved in immune response

0.76	GO:0030983	mismatched DNA binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0000400	four-way junction DNA binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.51	GO:0000406	double-strand/single-strand DNA junction binding
0.50	GO:0000403	Y-form DNA binding
0.49	GO:0032405	MutLalpha complex binding
0.49	GO:0032357	oxidized purine DNA binding

0.82	GO:0032300	mismatch repair complex
0.53	GO:0044428	nuclear part
0.38	GO:0005694	chromosome
0.38	GO:0043233	organelle lumen
0.34	GO:0000922	spindle pole
0.33	GO:0005815	microtubule organizing center
0.30	GO:0016020	membrane

0.43

GO:0016887

tr|T1FSF2|T1FSF2_HELRO
Uncharacterized protein
Search

tr|T1FSF3|T1FSF3_HELRO
Palmitoyltransferase
Search

0.32	Palmitoyltransferase

0.39	GO:0009651	response to salt stress
0.39	GO:0018345	protein palmitoylation
0.39	GO:0099402	plant organ development
0.36	GO:0006612	protein targeting to membrane

0.78

GO:0019706

protein-cysteine S-palmitoyltransferase activity

0.39	GO:0009705	plant-type vacuole membrane
0.37	GO:0031211	endoplasmic reticulum palmitoyltransferase complex
0.37	GO:0032541	cortical endoplasmic reticulum
0.37	GO:0097038	perinuclear endoplasmic reticulum
0.36	GO:0030176	integral component of endoplasmic reticulum membrane
0.33	GO:0005886	plasma membrane

0.78

EC:2.3.1.225

GO:0019706

tr|T1FSF4|T1FSF4_HELRO
Uncharacterized protein
Search

0.72	GO:0051895	negative regulation of focal adhesion assembly
0.72	GO:2000251	positive regulation of actin cytoskeleton reorganization
0.71	GO:0071391	cellular response to estrogen stimulus
0.71	GO:0034260	negative regulation of GTPase activity
0.71	GO:0051491	positive regulation of filopodium assembly
0.69	GO:0010595	positive regulation of endothelial cell migration
0.69	GO:0090630	activation of GTPase activity
0.68	GO:0090316	positive regulation of intracellular protein transport
0.68	GO:0035148	tube formation
0.67	GO:0007030	Golgi organization

0.74	GO:0010698	acetyltransferase activator activity
0.72	GO:0035035	histone acetyltransferase binding
0.69	GO:0035257	nuclear hormone receptor binding
0.69	GO:0048487	beta-tubulin binding
0.65	GO:0042393	histone binding
0.64	GO:0003682	chromatin binding
0.41	GO:0004931	extracellularly ATP-gated cation channel activity
0.40	GO:0001614	purinergic nucleotide receptor activity
0.36	GO:0030515	snoRNA binding
0.35	GO:0003887	DNA-directed DNA polymerase activity

0.70	GO:0035327	transcriptionally active chromatin
0.68	GO:0005881	cytoplasmic microtubule
0.66	GO:0031252	cell leading edge
0.65	GO:0045111	intermediate filament cytoskeleton
0.61	GO:0005730	nucleolus
0.48	GO:0071944	cell periphery
0.39	GO:0098794	postsynapse
0.36	GO:0008622	epsilon DNA polymerase complex
0.30	GO:0016020	membrane

0.35

GO:0003887

tr|T1FSF5|T1FSF5_HELRO
Uncharacterized protein
Search

tr|T1FSF6|T1FSF6_HELRO
Uncharacterized protein
Search

0.41	GO:0034134	toll-like receptor 2 signaling pathway
0.41	GO:0050729	positive regulation of inflammatory response
0.41	GO:0002755	MyD88-dependent toll-like receptor signaling pathway
0.40	GO:0050707	regulation of cytokine secretion
0.40	GO:0002237	response to molecule of bacterial origin
0.40	GO:0006954	inflammatory response
0.40	GO:0045087	innate immune response
0.37	GO:0016310	phosphorylation
0.36	GO:0000278	mitotic cell cycle
0.36	GO:0036211	protein modification process

0.38	GO:0016301	kinase activity
0.36	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0140096	catalytic activity, acting on a protein

0.30

GO:0016020

membrane

0.36

GO:0016773

tr|T1FSF7|T1FSF7_HELRO
Uncharacterized protein
Search

0.63	GO:0006468	protein phosphorylation
0.33	GO:2001141	regulation of RNA biosynthetic process
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.64	GO:0004672	protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0001871	pattern binding
0.33	GO:0003676	nucleic acid binding
0.33	GO:0005509	calcium ion binding
0.33	GO:0030246	carbohydrate binding

0.30

GO:0031224

intrinsic component of membrane

tr|T1FSF8|T1FSF8_HELRO
Uncharacterized protein
Search

0.10	Calpain family cysteine protease

0.61	GO:0006508	proteolysis
0.51	GO:0010634	positive regulation of epithelial cell migration
0.34	GO:0016255	attachment of GPI anchor to protein

0.82	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.55	GO:0090541	MIT domain binding
0.33	GO:0005198	structural molecule activity

0.45	GO:0005622	intracellular
0.36	GO:0070062	extracellular exosome
0.33	GO:0099512	supramolecular fiber
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0044422	organelle part
0.33	GO:1902494	catalytic complex
0.32	GO:0043228	non-membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

tr|T1FSF9|T1FSF9_HELRO
Uncharacterized protein
Search

tr|T1FSG0|T1FSG0_HELRO
Uncharacterized protein
Search

0.55	Synaptophysin

0.82	GO:0008021	synaptic vesicle
0.44	GO:0099501	exocytic vesicle membrane
0.42	GO:0031301	integral component of organelle membrane

tr|T1FSG1|T1FSG1_HELRO
Uncharacterized protein
Search

0.41	GO:0030036	actin cytoskeleton organization
0.40	GO:0030154	cell differentiation
0.39	GO:0045614	negative regulation of plasmatocyte differentiation
0.39	GO:0035203	regulation of lamellocyte differentiation
0.38	GO:0048139	female germ-line cyst encapsulation
0.38	GO:0030725	germline ring canal formation
0.38	GO:0048149	behavioral response to ethanol
0.38	GO:0007616	long-term memory
0.38	GO:0048581	negative regulation of post-embryonic development
0.37	GO:1903707	negative regulation of hemopoiesis

0.74	GO:0003779	actin binding
0.45	GO:0032403	protein complex binding
0.35	GO:0030246	carbohydrate binding
0.33	GO:0004252	serine-type endopeptidase activity

0.39	GO:0035182	female germline ring canal outer rim
0.39	GO:0035183	female germline ring canal inner rim
0.38	GO:0045179	apical cortex
0.37	GO:0070938	contractile ring
0.37	GO:0030018	Z disc
0.37	GO:0005884	actin filament
0.37	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0005829	cytosol
0.34	GO:0005634	nucleus
0.34	GO:0005886	plasma membrane

0.33

GO:0004252

tr|T1FSG2|T1FSG2_HELRO
Uncharacterized protein
Search

tr|T1FSG3|T1FSG3_HELRO
Uncharacterized protein
Search

0.72	GO:0042609	CD4 receptor binding
0.37	GO:0016787	hydrolase activity

0.75	GO:0030140	trans-Golgi network transport vesicle
0.65	GO:0005829	cytosol
0.50	GO:0043231	intracellular membrane-bounded organelle

0.37

GO:0016787

tr|T1FSG4|T1FSG4_HELRO
Uncharacterized protein
Search

CUL2

0.91	Testis secretory sperm-binding protein Li 238E

0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.45	GO:0048140	male germ-line cyst encapsulation
0.45	GO:0007295	growth of a germarium-derived egg chamber
0.44	GO:0008582	regulation of synaptic growth at neuromuscular junction
0.43	GO:0030514	negative regulation of BMP signaling pathway
0.42	GO:0016567	protein ubiquitination
0.40	GO:0001944	vasculature development
0.40	GO:0043009	chordate embryonic development
0.35	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia
0.34	GO:0097193	intrinsic apoptotic signaling pathway

0.79	GO:0031625	ubiquitin protein ligase binding
0.43	GO:0061630	ubiquitin protein ligase activity
0.36	GO:0032403	protein complex binding
0.33	GO:0016874	ligase activity

0.77	GO:0031461	cullin-RING ubiquitin ligase complex
0.45	GO:0005654	nucleoplasm
0.42	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0005730	nucleolus
0.38	GO:0030891	VCB complex
0.33	GO:0005829	cytosol

0.33

GO:0016874

tr|T1FSG5|T1FSG5_HELRO
Uncharacterized protein
Search

0.44	Zinc finger protein, putative (Fragment)

0.67

GO:0071897

DNA biosynthetic process

0.71

GO:0003887

DNA-directed DNA polymerase activity

0.71

GO:0003887

tr|T1FSG6|T1FSG6_HELRO
Uncharacterized protein
Search

tr|T1FSG7|T1FSG7_HELRO
Uncharacterized protein
Search

0.59	Rho-associated protein kinase 1 (Fragment)

0.72	GO:0007266	Rho protein signal transduction
0.70	GO:0051492	regulation of stress fiber assembly
0.64	GO:2000114	regulation of establishment of cell polarity
0.62	GO:0006468	protein phosphorylation
0.60	GO:0030036	actin cytoskeleton organization
0.52	GO:0051451	myoblast migration
0.52	GO:0032060	bleb assembly
0.52	GO:0140058	neuron projection arborization
0.52	GO:0051894	positive regulation of focal adhesion assembly
0.52	GO:0003383	apical constriction

0.74	GO:0017048	Rho GTPase binding
0.68	GO:0004674	protein serine/threonine kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0008144	drug binding
0.52	GO:0046872	metal ion binding
0.38	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity

0.54	GO:0005856	cytoskeleton
0.50	GO:0106003	amyloid-beta complex
0.50	GO:0001726	ruffle
0.49	GO:0030027	lamellipodium
0.40	GO:0032059	bleb
0.40	GO:0005886	plasma membrane
0.37	GO:0000139	Golgi membrane
0.35	GO:0034774	secretory granule lumen
0.34	GO:0005773	vacuole
0.33	GO:0005829	cytosol

0.68

GO:0004674

tr|T1FSG8|T1FSG8_HELRO
Uncharacterized protein
Search

tr|T1FSG9|T1FSG9_HELRO
Uncharacterized protein
Search

0.17	WAS/WASL interacting protein family, member 2a

0.74

GO:0003779

actin binding

tr|T1FSH0|T1FSH0_HELRO
Delta-like protein
Search

0.82	GO:0007219	Notch signaling pathway
0.69	GO:0007275	multicellular organism development
0.54	GO:0060563	neuroepithelial cell differentiation
0.54	GO:0045747	positive regulation of Notch signaling pathway
0.53	GO:0009913	epidermal cell differentiation
0.51	GO:0045602	negative regulation of endothelial cell differentiation
0.51	GO:2000737	negative regulation of stem cell differentiation
0.51	GO:0002456	T cell mediated immunity
0.51	GO:0002009	morphogenesis of an epithelium
0.51	GO:0097150	neuronal stem cell population maintenance

0.85	GO:0005112	Notch binding
0.70	GO:0005509	calcium ion binding
0.46	GO:0005543	phospholipid binding
0.43	GO:0008083	growth factor activity
0.33	GO:0004872	receptor activity
0.33	GO:0005198	structural molecule activity

0.48	GO:0016324	apical plasma membrane
0.47	GO:0005912	adherens junction
0.40	GO:0005887	integral component of plasma membrane
0.33	GO:0005576	extracellular region

tr|T1FSH1|T1FSH1_HELRO
Uncharacterized protein
Search

0.76	GO:0035091	phosphatidylinositol binding
0.63	GO:0008270	zinc ion binding
0.51	GO:0003676	nucleic acid binding

tr|T1FSH2|T1FSH2_HELRO
Uncharacterized protein
Search

0.87	GO:0000493	box H/ACA snoRNP assembly
0.38	GO:0006508	proteolysis

0.71	GO:0051082	unfolded protein binding
0.41	GO:0008234	cysteine-type peptidase activity

0.70	GO:0005654	nucleoplasm
0.52	GO:0005829	cytosol

0.41

GO:0008234

tr|T1FSH3|T1FSH3_HELRO
Uncharacterized protein
Search

tr|T1FSH4|T1FSH4_HELRO
Uncharacterized protein
Search

tr|T1FSH5|T1FSH5_HELRO
Receptor protein-tyrosine kinase
Search

0.38	Receptor protein-tyrosine kinase

0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.74	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.54	GO:0023014	signal transduction by protein phosphorylation
0.52	GO:0035556	intracellular signal transduction
0.39	GO:0008071	maternal determination of dorsal/ventral axis, ovarian follicular epithelium, soma encoded
0.39	GO:0035310	notum cell fate specification
0.39	GO:0046673	negative regulation of compound eye retinal cell programmed cell death
0.39	GO:0007395	dorsal closure, spreading of leading edge cells
0.39	GO:0016330	second mitotic wave involved in compound eye morphogenesis
0.39	GO:0007479	leg disc proximal/distal pattern formation

0.78	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.68	GO:0004716	signal transducer, downstream of receptor, with protein tyrosine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.33	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.32	GO:0016787	hydrolase activity

0.40	GO:0005622	intracellular
0.39	GO:0035230	cytoneme
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.78

EC:2.7.10.1

GO:0004714

tr|T1FSH6|T1FSH6_HELRO
Uncharacterized protein
Search

tr|T1FSH7|T1FSH7_HELRO
Uncharacterized protein
Search

0.10	Putative transducin beta-like protein 3

0.68	GO:0006364	rRNA processing
0.45	GO:0042274	ribosomal small subunit biogenesis
0.42	GO:0048538	thymus development
0.41	GO:0030098	lymphocyte differentiation
0.39	GO:0010564	regulation of cell cycle process
0.39	GO:0009880	embryonic pattern specification
0.39	GO:0034471	ncRNA 5'-end processing
0.38	GO:0009793	embryo development ending in seed dormancy
0.37	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.36	GO:0051301	cell division

0.49	GO:0030515	snoRNA binding
0.33	GO:0030695	GTPase regulator activity
0.33	GO:0004674	protein serine/threonine kinase activity
0.33	GO:0005515	protein binding
0.31	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.79	GO:0032040	small-subunit processome
0.50	GO:0005730	nucleolus
0.48	GO:0030686	90S preribosome
0.41	GO:0043234	protein complex
0.33	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

0.33

GO:0004674

tr|T1FSH8|T1FSH8_HELRO
Uncharacterized protein
Search

CHM

0.76	Rab proteins geranylgeranyltransferase component A 1

0.84	GO:0018344	protein geranylgeranylation
0.77	GO:0007264	small GTPase mediated signal transduction
0.69	GO:0006886	intracellular protein transport
0.69	GO:0050790	regulation of catalytic activity
0.45	GO:0090150	establishment of protein localization to membrane
0.40	GO:0048798	swim bladder inflation
0.40	GO:0050935	iridophore differentiation
0.39	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound
0.39	GO:0010842	retina layer formation
0.39	GO:0042491	inner ear auditory receptor cell differentiation

0.83	GO:0005092	GDP-dissociation inhibitor activity
0.48	GO:0017137	Rab GTPase binding
0.44	GO:0016740	transferase activity
0.37	GO:0005096	GTPase activator activity
0.35	GO:0140096	catalytic activity, acting on a protein

0.84	GO:0005968	Rab-protein geranylgeranyltransferase complex
0.44	GO:0005829	cytosol
0.40	GO:0005818	aster
0.39	GO:0000922	spindle pole
0.39	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0005654	nucleoplasm
0.33	GO:0008021	synaptic vesicle
0.30	GO:0016020	membrane

0.44

GO:0016740

tr|T1FSH9|T1FSH9_HELRO
Uncharacterized protein
Search

0.65	GO:0072659	protein localization to plasma membrane
0.60	GO:0046854	phosphatidylinositol phosphorylation
0.56	GO:0042552	myelination
0.50	GO:0098656	anion transmembrane transport
0.50	GO:0015698	inorganic anion transport
0.40	GO:0045454	cell redox homeostasis

0.57

GO:0005452

inorganic anion exchanger activity

0.56	GO:0005829	cytosol
0.53	GO:0043005	neuron projection
0.47	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1FSI0|T1FSI0_HELRO
Uncharacterized protein
Search

tr|T1FSI1|T1FSI1_HELRO
Uncharacterized protein
Search

tr|T1FSI2|T1FSI2_HELRO
Uncharacterized protein
Search

0.65	GO:0006414	translational elongation
0.48	GO:0042254	ribosome biogenesis
0.43	GO:0002181	cytoplasmic translation
0.42	GO:0032147	activation of protein kinase activity
0.36	GO:0010043	response to zinc ion
0.36	GO:0009735	response to cytokinin
0.36	GO:0046686	response to cadmium ion
0.36	GO:0009651	response to salt stress
0.36	GO:0009409	response to cold

0.60	GO:0003735	structural constituent of ribosome
0.43	GO:0030295	protein kinase activator activity
0.35	GO:0005507	copper ion binding

0.61	GO:0005840	ribosome
0.43	GO:0044445	cytosolic part
0.40	GO:0044446	intracellular organelle part
0.36	GO:0005844	polysome
0.36	GO:0055044	symplast
0.36	GO:0048046	apoplast
0.35	GO:0005911	cell-cell junction
0.34	GO:0043233	organelle lumen
0.34	GO:0009507	chloroplast
0.34	GO:0005634	nucleus

tr|T1FSI3|T1FSI3_HELRO
Uncharacterized protein
Search

0.10	Ectonucleoside triphosphate diphosphohydrolase 7

0.45	GO:0009195	pyrimidine ribonucleoside diphosphate catabolic process
0.45	GO:0046048	UDP metabolic process
0.45	GO:0009222	pyrimidine ribonucleotide catabolic process
0.42	GO:0046133	pyrimidine ribonucleoside catabolic process
0.36	GO:0034656	nucleobase-containing small molecule catabolic process
0.35	GO:0046032	ADP catabolic process
0.35	GO:0046712	GDP catabolic process
0.34	GO:0060050	positive regulation of protein glycosylation
0.34	GO:0035262	gonad morphogenesis
0.34	GO:0030334	regulation of cell migration

0.51	GO:0016787	hydrolase activity
0.34	GO:0005201	extracellular matrix structural constituent
0.34	GO:0046872	metal ion binding

0.44	GO:0097636	intrinsic component of autophagosome membrane
0.43	GO:0031166	integral component of vacuolar membrane
0.42	GO:0030173	integral component of Golgi membrane
0.37	GO:0030659	cytoplasmic vesicle membrane
0.34	GO:0030139	endocytic vesicle
0.32	GO:0005739	mitochondrion

0.51

GO:0016787

tr|T1FSI4|T1FSI4_HELRO
Uncharacterized protein
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tr|T1FSI5|T1FSI5_HELRO
Uncharacterized protein
Search

tr|T1FSI6|T1FSI6_HELRO
Uncharacterized protein
Search

0.39	GO:0060255	regulation of macromolecule metabolic process
0.38	GO:0005992	trehalose biosynthetic process
0.38	GO:0080090	regulation of primary metabolic process
0.38	GO:0031326	regulation of cellular biosynthetic process
0.38	GO:0051171	regulation of nitrogen compound metabolic process
0.37	GO:0016567	protein ubiquitination
0.37	GO:0044085	cellular component biogenesis
0.37	GO:0016070	RNA metabolic process
0.37	GO:0007219	Notch signaling pathway
0.37	GO:0010467	gene expression

0.43	GO:0001871	pattern binding
0.41	GO:0030246	carbohydrate binding
0.38	GO:0140096	catalytic activity, acting on a protein
0.38	GO:0140110	transcription regulator activity
0.37	GO:0046982	protein heterodimerization activity
0.37	GO:0005524	ATP binding
0.37	GO:0005545	1-phosphatidylinositol binding
0.37	GO:0005044	scavenger receptor activity
0.37	GO:0030276	clathrin binding
0.37	GO:0016301	kinase activity

0.60	GO:0071203	WASH complex
0.42	GO:0005634	nucleus
0.42	GO:0070701	mucus layer
0.41	GO:0031248	protein acetyltransferase complex
0.40	GO:0031974	membrane-enclosed lumen
0.39	GO:0032040	small-subunit processome
0.38	GO:0044446	intracellular organelle part
0.38	GO:0000428	DNA-directed RNA polymerase complex
0.37	GO:0005667	transcription factor complex
0.37	GO:1905368	peptidase complex

0.37

EC:6.3.4.14

GO:0004075

tr|T1FSI7|T1FSI7_HELRO
Uncharacterized protein
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tr|T1FSI8|T1FSI8_HELRO
Uncharacterized protein
Search

tr|T1FSI9|T1FSI9_HELRO
Receptor protein-tyrosine kinase
Search

0.38	Receptor protein-tyrosine kinase

0.75	GO:0018108	peptidyl-tyrosine phosphorylation
0.63	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.52	GO:0000187	activation of MAPK activity
0.49	GO:0030154	cell differentiation
0.48	GO:0007399	nervous system development
0.42	GO:0046777	protein autophosphorylation
0.41	GO:0045087	innate immune response
0.41	GO:0042127	regulation of cell proliferation
0.34	GO:0007498	mesoderm development
0.34	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules

0.75	GO:0004713	protein tyrosine kinase activity
0.65	GO:0019199	transmembrane receptor protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0005102	receptor binding
0.33	GO:0005509	calcium ion binding
0.33	GO:0008270	zinc ion binding
0.32	GO:0003676	nucleic acid binding

0.41	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.39	GO:0005856	cytoskeleton
0.35	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.75

EC:2.7.10

GO:0004713

tr|T1FSJ0|T1FSJ0_HELRO
Uncharacterized protein
Search

tr|T1FSJ1|T1FSJ1_HELRO
Uncharacterized protein
Search

0.69	GO:0006886	intracellular protein transport
0.58	GO:0007165	signal transduction
0.52	GO:0016197	endosomal transport
0.43	GO:0098876	vesicle-mediated transport to the plasma membrane
0.36	GO:1990884	RNA acetylation
0.35	GO:0005975	carbohydrate metabolic process
0.35	GO:0042274	ribosomal small subunit biogenesis
0.34	GO:0000154	rRNA modification
0.34	GO:0006400	tRNA modification
0.34	GO:0007041	lysosomal transport

0.79	GO:0032266	phosphatidylinositol-3-phosphate binding
0.36	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.35	GO:0005515	protein binding
0.35	GO:0008080	N-acetyltransferase activity
0.34	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.45	GO:0005622	intracellular
0.40	GO:0031982	vesicle
0.39	GO:0012505	endomembrane system
0.37	GO:0001772	immunological synapse
0.36	GO:0031974	membrane-enclosed lumen
0.35	GO:0043228	non-membrane-bounded organelle
0.35	GO:0044422	organelle part
0.34	GO:0098796	membrane protein complex
0.33	GO:0098805	whole membrane
0.30	GO:0016021	integral component of membrane

0.36	EC:3.2.1	GO:0004553
0.34	KEGG:R05795	GO:0035005

tr|T1FSJ2|T1FSJ2_HELRO
Uncharacterized protein
Search

tr|T1FSJ3|T1FSJ3_HELRO
Non-specific serine/threonine protein kinase
Search

0.23	Non-specific serine/threonine protein kinase

0.62	GO:0006468	protein phosphorylation
0.45	GO:0018212	peptidyl-tyrosine modification
0.45	GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress
0.44	GO:0061351	neural precursor cell proliferation
0.44	GO:0048821	erythrocyte development
0.43	GO:0008016	regulation of heart contraction
0.42	GO:0043065	positive regulation of apoptotic process
0.34	GO:0043066	negative regulation of apoptotic process

0.69	GO:0004674	protein serine/threonine kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.41	GO:0005509	calcium ion binding

0.42	GO:0005938	cell cortex
0.39	GO:0005634	nucleus
0.37	GO:0005886	plasma membrane

0.69

GO:0004674

tr|T1FSJ4|T1FSJ4_HELRO
Uncharacterized protein
Search

0.10	Angel homolog 2 (Drosophila)

0.57	GO:0007623	circadian rhythm
0.56	GO:0048255	mRNA stabilization
0.54	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic
0.48	GO:0033962	cytoplasmic mRNA processing body assembly
0.48	GO:0045668	negative regulation of osteoblast differentiation
0.48	GO:0045600	positive regulation of fat cell differentiation
0.47	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA
0.47	GO:0042752	regulation of circadian rhythm
0.47	GO:0045995	regulation of embryonic development
0.47	GO:0032496	response to lipopolysaccharide

0.68	GO:0008190	eukaryotic initiation factor 4E binding
0.60	GO:0019904	protein domain specific binding
0.59	GO:0004535	poly(A)-specific ribonuclease activity
0.51	GO:0003729	mRNA binding
0.37	GO:0004519	endonuclease activity
0.33	GO:0046872	metal ion binding

0.65	GO:0048471	perinuclear region of cytoplasm
0.64	GO:0005801	cis-Golgi network
0.56	GO:0005783	endoplasmic reticulum
0.55	GO:0005829	cytosol
0.55	GO:0005634	nucleus
0.46	GO:0000932	P-body
0.43	GO:0031974	membrane-enclosed lumen
0.39	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.59

EC:3.1.13.4

GO:0004535

tr|T1FSJ5|T1FSJ5_HELRO
Uncharacterized protein
Search

0.52

GO:0090305

nucleic acid phosphodiester bond hydrolysis

0.55	GO:0004527	exonuclease activity
0.49	GO:0030554	adenyl nucleotide binding
0.48	GO:0097367	carbohydrate derivative binding
0.48	GO:0008144	drug binding
0.48	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0046872	metal ion binding

tr|T1FSJ6|T1FSJ6_HELRO
Uncharacterized protein
Search

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.38	GO:0006086	acetyl-CoA biosynthetic process from pyruvate
0.34	GO:0055114	oxidation-reduction process

0.72	GO:0004930	G-protein coupled receptor activity
0.71	GO:0001653	peptide receptor activity
0.37	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity

0.40	GO:0005887	integral component of plasma membrane
0.34	GO:0043227	membrane-bounded organelle
0.34	GO:0043229	intracellular organelle

0.37

EC:1.2.4.1

GO:0004739

tr|T1FSJ7|T1FSJ7_HELRO
Uncharacterized protein
Search

HGSNAT

0.61	Heparan-alpha-glucosaminide N-acetyltransferase

0.51	GO:0007041	lysosomal transport
0.45	GO:0051259	protein oligomerization
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0006027	glycosaminoglycan catabolic process

0.47

GO:0016740

transferase activity

0.50	GO:0005765	lysosomal membrane
0.35	GO:0035579	specific granule membrane
0.35	GO:0070821	tertiary granule membrane
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.47

GO:0016740

tr|T1FSJ8|T1FSJ8_HELRO
Uncharacterized protein
Search

tr|T1FSJ9|T1FSJ9_HELRO
Uncharacterized protein
Search

tr|T1FSK0|T1FSK0_HELRO
Uncharacterized protein
Search

0.56	GO:0006468	protein phosphorylation
0.41	GO:0007155	cell adhesion
0.40	GO:0035023	regulation of Rho protein signal transduction
0.39	GO:0048731	system development
0.38	GO:0090497	mesenchymal cell migration
0.38	GO:0035335	peptidyl-tyrosine dephosphorylation
0.38	GO:0035122	embryonic medial fin morphogenesis
0.37	GO:0065009	regulation of molecular function
0.37	GO:0060322	head development
0.37	GO:0120039	plasma membrane bounded cell projection morphogenesis

0.57	GO:0004672	protein kinase activity
0.50	GO:0032559	adenyl ribonucleotide binding
0.49	GO:0008144	drug binding
0.49	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0005509	calcium ion binding
0.40	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.38	GO:0004725	protein tyrosine phosphatase activity

0.44	GO:0005604	basement membrane
0.42	GO:0005938	cell cortex
0.42	GO:0030054	cell junction
0.39	GO:0070062	extracellular exosome
0.37	GO:0097610	cell surface furrow
0.36	GO:0032155	cell division site part
0.30	GO:0016020	membrane

0.38

GO:0004725

tr|T1FSK1|T1FSK1_HELRO
Uncharacterized protein
Search

tr|T1FSK2|T1FSK2_HELRO
Uncharacterized protein
Search

0.37

GO:0022008

neurogenesis

0.32	GO:0005840	ribosome
0.30	GO:0044425	membrane part

tr|T1FSK3|T1FSK3_HELRO
Uncharacterized protein
Search

tr|T1FSK4|T1FSK4_HELRO
Uncharacterized protein
Search

tr|T1FSK5|T1FSK5_HELRO
Uncharacterized protein
Search

tr|T1FSK6|T1FSK6_HELRO
Uncharacterized protein
Search

tr|T1FSK7|T1FSK7_HELRO
Uncharacterized protein
Search

TRAP1

0.87	TNF receptor associated protein 1

0.70	GO:0009386	translational attenuation
0.69	GO:0006457	protein folding
0.68	GO:1901856	negative regulation of cellular respiration
0.62	GO:0006950	response to stress

0.71	GO:0051082	unfolded protein binding
0.59	GO:0019901	protein kinase binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.58	GO:0005759	mitochondrial matrix
0.54	GO:0005654	nucleoplasm
0.49	GO:0031966	mitochondrial membrane
0.49	GO:0019866	organelle inner membrane

tr|T1FSK8|T1FSK8_HELRO
Uncharacterized protein
Search

tr|T1FSK9|T1FSK9_HELRO
Uncharacterized protein
Search

0.76	GO:0010951	negative regulation of endopeptidase activity
0.58	GO:0006508	proteolysis
0.49	GO:0006030	chitin metabolic process
0.42	GO:0030198	extracellular matrix organization
0.35	GO:0007229	integrin-mediated signaling pathway
0.33	GO:0007275	multicellular organism development
0.33	GO:0032504	multicellular organism reproduction
0.33	GO:0000902	cell morphogenesis

0.79	GO:0004867	serine-type endopeptidase inhibitor activity
0.58	GO:0008233	peptidase activity
0.49	GO:0008061	chitin binding
0.43	GO:0005201	extracellular matrix structural constituent

0.62	GO:0005576	extracellular region
0.34	GO:0005581	collagen trimer
0.30	GO:0016020	membrane

0.58

GO:0008233

tr|T1FSL0|T1FSL0_HELRO
Uncharacterized protein
Search

tr|T1FSL1|T1FSL1_HELRO
Uncharacterized protein
Search

FZD7

0.92	Frizzled class receptor 7

0.77	GO:0016055	Wnt signaling pathway
0.70	GO:0007275	multicellular organism development
0.55	GO:0042666	negative regulation of ectodermal cell fate specification
0.54	GO:0014834	skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration
0.53	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing
0.53	GO:2000726	negative regulation of cardiac muscle cell differentiation
0.53	GO:0060231	mesenchymal to epithelial transition
0.52	GO:0035412	regulation of catenin import into nucleus
0.52	GO:0048103	somatic stem cell division
0.51	GO:0034446	substrate adhesion-dependent cell spreading

0.83	GO:0042813	Wnt-activated receptor activity
0.57	GO:0017147	Wnt-protein binding
0.52	GO:0005109	frizzled binding
0.51	GO:0030165	PDZ domain binding
0.51	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.45	GO:0004930	G-protein coupled receptor activity
0.39	GO:0045545	syndecan binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.51	GO:0055038	recycling endosome membrane
0.42	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1FSL2|T1FSL2_HELRO
Uncharacterized protein
Search

0.57	GO:0007165	signal transduction
0.39	GO:0099120	socially cooperative development
0.39	GO:1903666	positive regulation of asexual reproduction
0.38	GO:0001708	cell fate specification
0.38	GO:0043085	positive regulation of catalytic activity
0.37	GO:0071230	cellular response to amino acid stimulus
0.37	GO:0030307	positive regulation of cell growth
0.37	GO:0043486	histone exchange
0.37	GO:0008361	regulation of cell size
0.37	GO:0019954	asexual reproduction

0.38	GO:0005515	protein binding
0.37	GO:0060090	molecular adaptor activity
0.37	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
0.36	GO:0003676	nucleic acid binding
0.36	GO:0005096	GTPase activator activity
0.36	GO:0003774	motor activity
0.35	GO:0005509	calcium ion binding
0.35	GO:0016875	ligase activity, forming carbon-oxygen bonds
0.35	GO:0140101	catalytic activity, acting on a tRNA
0.34	GO:0003700	DNA binding transcription factor activity

0.39	GO:0005634	nucleus
0.38	GO:0000792	heterochromatin
0.37	GO:0020011	apicoplast
0.37	GO:0005776	autophagosome
0.37	GO:0031931	TORC1 complex
0.30	GO:0031224	intrinsic component of membrane

0.37	EC:3.2.1.113	GO:0004571
0.37	KEGG:R05982 KEGG:R06722	GO:0004571

tr|T1FSL3|T1FSL3_HELRO
Uncharacterized protein
Search

0.47	GO:0030154	cell differentiation
0.47	GO:0007399	nervous system development
0.42	GO:0065007	biological regulation
0.40	GO:0016567	protein ubiquitination
0.40	GO:0050896	response to stimulus
0.40	GO:0007155	cell adhesion
0.39	GO:0023052	signaling
0.39	GO:0007154	cell communication
0.39	GO:0030198	extracellular matrix organization
0.38	GO:0006366	transcription by RNA polymerase II

0.41	GO:0046872	metal ion binding
0.40	GO:0003723	RNA binding
0.40	GO:0003700	DNA binding transcription factor activity
0.40	GO:0004842	ubiquitin-protein transferase activity
0.40	GO:0004222	metalloendopeptidase activity
0.39	GO:0008201	heparin binding
0.39	GO:0001085	RNA polymerase II transcription factor binding
0.39	GO:0030414	peptidase inhibitor activity
0.38	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.38	GO:0050840	extracellular matrix binding

0.42	GO:0005576	extracellular region
0.40	GO:0005634	nucleus
0.38	GO:0005667	transcription factor complex
0.37	GO:0031091	platelet alpha granule
0.36	GO:0009897	external side of plasma membrane
0.35	GO:0005874	microtubule
0.30	GO:0016021	integral component of membrane

0.40	EC:3.4.24	GO:0004222
0.40	KEGG:R03876	GO:0004842

tr|T1FSL4|T1FSL4_HELRO
Uncharacterized protein
Search

0.45	GO:0048015	phosphatidylinositol-mediated signaling
0.43	GO:0046854	phosphatidylinositol phosphorylation
0.41	GO:0034968	histone lysine methylation
0.38	GO:0048208	COPII vesicle coating
0.38	GO:0007224	smoothened signaling pathway
0.38	GO:0009298	GDP-mannose biosynthetic process
0.37	GO:0015031	protein transport
0.37	GO:0006030	chitin metabolic process
0.37	GO:1903506	regulation of nucleic acid-templated transcription
0.37	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.46	GO:0003723	RNA binding
0.42	GO:0018024	histone-lysine N-methyltransferase activity
0.38	GO:0008270	zinc ion binding
0.38	GO:0016301	kinase activity
0.37	GO:0004476	mannose-6-phosphate isomerase activity
0.37	GO:0008061	chitin binding
0.37	GO:0003700	DNA binding transcription factor activity
0.36	GO:0003777	microtubule motor activity
0.36	GO:0008017	microtubule binding
0.36	GO:0043565	sequence-specific DNA binding

0.38	GO:0032777	Piccolo NuA4 histone acetyltransferase complex
0.37	GO:0000139	Golgi membrane
0.35	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.42

GO:0018024

tr|T1FSL5|T1FSL5_HELRO
Uncharacterized protein
Search

0.73	Leukotriene-B(4) omega-hydroxylase 1

0.53	GO:0055114	oxidation-reduction process
0.35	GO:0016539	intein-mediated protein splicing
0.33	GO:0030258	lipid modification
0.33	GO:0006631	fatty acid metabolic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.66	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding

0.33	GO:0005789	endoplasmic reticulum membrane
0.32	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.68

EC:1.14

GO:0016705

tr|T1FSL6|T1FSL6_HELRO
Uncharacterized protein
Search

tr|T1FSL7|T1FSL7_HELRO
Uncharacterized protein
Search

tr|T1FSL8|T1FSL8_HELRO
Uncharacterized protein
Search

tr|T1FSL9|T1FSL9_HELRO
Uncharacterized protein
Search

0.39	GO:0030244	cellulose biosynthetic process
0.38	GO:0006011	UDP-glucose metabolic process
0.36	GO:0009607	response to biotic stimulus
0.34	GO:0006886	intracellular protein transport
0.34	GO:0030163	protein catabolic process
0.33	GO:0006508	proteolysis
0.33	GO:0060271	cilium assembly
0.33	GO:0006396	RNA processing
0.33	GO:0030334	regulation of cell migration
0.33	GO:0006888	ER to Golgi vesicle-mediated transport

0.57	GO:0045735	nutrient reservoir activity
0.39	GO:0005544	calcium-dependent phospholipid binding
0.37	GO:0005509	calcium ion binding
0.34	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0008270	zinc ion binding
0.33	GO:0003774	motor activity
0.33	GO:0003743	translation initiation factor activity
0.33	GO:0016791	phosphatase activity
0.33	GO:0017171	serine hydrolase activity
0.33	GO:0032559	adenyl ribonucleotide binding

0.36	GO:0019867	outer membrane
0.34	GO:0012505	endomembrane system
0.34	GO:0043227	membrane-bounded organelle
0.33	GO:0043229	intracellular organelle
0.33	GO:0030117	membrane coat
0.33	GO:0098805	whole membrane
0.33	GO:0009425	bacterial-type flagellum basal body
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.33

EC:3.1.3 EC:3.1.3.41

GO:0016791

tr|T1FSM0|T1FSM0_HELRO
Uncharacterized protein
Search

0.59	GO:0009607	response to biotic stimulus
0.40	GO:0006471	protein ADP-ribosylation
0.40	GO:0006030	chitin metabolic process
0.39	GO:0006508	proteolysis
0.35	GO:1903506	regulation of nucleic acid-templated transcription

0.41	GO:0005509	calcium ion binding
0.41	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity
0.41	GO:0004252	serine-type endopeptidase activity
0.41	GO:0005544	calcium-dependent phospholipid binding
0.39	GO:0008061	chitin binding
0.39	GO:0003713	transcription coactivator activity

0.37	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.41

EC:2.4.2.31

GO:0003956

tr|T1FSM1|T1FSM1_HELRO
Uncharacterized protein
Search

tr|T1FSM2|T1FSM2_HELRO
Uncharacterized protein
Search

0.54	GO:0035186	syncytial blastoderm mitotic cell cycle
0.46	GO:0045892	negative regulation of transcription, DNA-templated
0.46	GO:0016458	gene silencing
0.44	GO:0045814	negative regulation of gene expression, epigenetic
0.44	GO:0051276	chromosome organization
0.42	GO:0030708	germarium-derived female germ-line cyst encapsulation
0.42	GO:0030713	ovarian follicle cell stalk formation
0.41	GO:0035075	response to ecdysone
0.41	GO:0021954	central nervous system neuron development
0.40	GO:0006032	chitin catabolic process

0.53	GO:0008270	zinc ion binding
0.48	GO:0051087	chaperone binding
0.48	GO:0003682	chromatin binding
0.45	GO:0008061	chitin binding
0.42	GO:0044547	DNA topoisomerase binding
0.41	GO:0030248	cellulose binding
0.40	GO:0008237	metallopeptidase activity
0.40	GO:0042302	structural constituent of cuticle
0.40	GO:0001104	RNA polymerase II transcription cofactor activity
0.39	GO:0003917	DNA topoisomerase type I activity

0.53	GO:0005634	nucleus
0.48	GO:0000151	ubiquitin ligase complex
0.46	GO:0031974	membrane-enclosed lumen
0.43	GO:0043234	protein complex
0.43	GO:0005694	chromosome
0.42	GO:0044446	intracellular organelle part
0.38	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.39

EC:5.99.1.2

GO:0003917

tr|T1FSM3|T1FSM3_HELRO
Uncharacterized protein
Search

0.70	GO:0006261	DNA-dependent DNA replication
0.66	GO:0071897	DNA biosynthetic process
0.44	GO:0097681	double-strand break repair via alternative nonhomologous end joining
0.39	GO:2000042	negative regulation of double-strand break repair via homologous recombination
0.38	GO:0051260	protein homooligomerization
0.37	GO:0006284	base-excision repair
0.37	GO:0006289	nucleotide-excision repair
0.36	GO:0010501	RNA secondary structure unwinding
0.34	GO:0016446	somatic hypermutation of immunoglobulin genes
0.34	GO:0090305	nucleic acid phosphodiester bond hydrolysis

0.71	GO:0003887	DNA-directed DNA polymerase activity
0.53	GO:0003677	DNA binding
0.51	GO:0032559	adenyl ribonucleotide binding
0.50	GO:0008144	drug binding
0.50	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0008409	5'-3' exonuclease activity
0.40	GO:0004386	helicase activity
0.40	GO:0051575	5'-deoxyribose-5-phosphate lyase activity
0.38	GO:0043142	single-stranded DNA-dependent ATPase activity
0.37	GO:0003682	chromatin binding

0.38	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0043232	intracellular non-membrane-bounded organelle
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.71

GO:0003887

tr|T1FSM4|T1FSM4_HELRO
Uncharacterized protein
Search

0.78	GO:0016573	histone acetylation
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.49	GO:0007464	R3/R4 cell fate commitment
0.48	GO:0040040	thermosensory behavior
0.48	GO:0045466	R7 cell differentiation
0.47	GO:0045475	locomotor rhythm
0.47	GO:0008347	glial cell migration
0.47	GO:0000076	DNA replication checkpoint

0.80	GO:0004402	histone acetyltransferase activity
0.75	GO:0003712	transcription cofactor activity
0.62	GO:0008270	zinc ion binding
0.48	GO:1990226	histone methyltransferase binding
0.46	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.43	GO:0008134	transcription factor binding

0.68	GO:0000123	histone acetyltransferase complex
0.46	GO:0005700	polytene chromosome
0.45	GO:0035097	histone methyltransferase complex
0.45	GO:0098793	presynapse
0.39	GO:0043234	protein complex
0.33	GO:0005681	spliceosomal complex
0.33	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.80

GO:0004402

tr|T1FSM5|T1FSM5_HELRO
Uncharacterized protein
Search

tr|T1FSM6|T1FSM6_HELRO
Uncharacterized protein
Search

WDR37

0.53	WD repeat-containing protein 37

0.74	GO:0000470	maturation of LSU-rRNA
0.73	GO:0000460	maturation of 5.8S rRNA
0.39	GO:0018108	peptidyl-tyrosine phosphorylation
0.37	GO:0055114	oxidation-reduction process

0.42	GO:0016905	myosin heavy chain kinase activity
0.40	GO:0004713	protein tyrosine kinase activity
0.38	GO:0016491	oxidoreductase activity

0.79	GO:0070545	PeBoW complex
0.73	GO:0030687	preribosome, large subunit precursor
0.30	GO:0031224	intrinsic component of membrane

0.42

EC:2.7.11.7

GO:0016905

tr|T1FSM7|T1FSM7_HELRO
Uncharacterized protein
Search

0.53	GO:1902685	positive regulation of receptor localization to synapse
0.51	GO:0010631	epithelial cell migration
0.51	GO:0007614	short-term memory
0.51	GO:0007379	segment specification
0.51	GO:0016322	neuron remodeling
0.50	GO:0008582	regulation of synaptic growth at neuromuscular junction
0.50	GO:0046622	positive regulation of organ growth
0.50	GO:0019730	antimicrobial humoral response
0.50	GO:0007350	blastoderm segmentation
0.49	GO:0007476	imaginal disc-derived wing morphogenesis

0.44	GO:0005515	protein binding
0.43	GO:0030554	adenyl nucleotide binding
0.43	GO:0097367	carbohydrate derivative binding
0.43	GO:0008144	drug binding
0.43	GO:0003676	nucleic acid binding
0.42	GO:0003700	DNA binding transcription factor activity
0.42	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0016817	hydrolase activity, acting on acid anhydrides
0.40	GO:0008270	zinc ion binding
0.39	GO:0004674	protein serine/threonine kinase activity

0.50	GO:0005634	nucleus
0.41	GO:0005667	transcription factor complex
0.40	GO:0005911	cell-cell junction
0.38	GO:0034708	methyltransferase complex
0.38	GO:0044446	intracellular organelle part
0.37	GO:0043232	intracellular non-membrane-bounded organelle
0.37	GO:0030134	COPII-coated ER to Golgi transport vesicle
0.37	GO:0070013	intracellular organelle lumen
0.36	GO:0030133	transport vesicle
0.36	GO:0012506	vesicle membrane

0.41

EC:3.6

GO:0016817

tr|T1FSM8|T1FSM8_HELRO
Uncharacterized protein
Search

0.47	GO:0006364	rRNA processing
0.44	GO:0000256	allantoin catabolic process
0.41	GO:0007018	microtubule-based movement
0.39	GO:0006359	regulation of transcription by RNA polymerase III
0.39	GO:0006383	transcription by RNA polymerase III
0.39	GO:0030245	cellulose catabolic process
0.39	GO:0015914	phospholipid transport
0.38	GO:0006518	peptide metabolic process
0.38	GO:0043604	amide biosynthetic process
0.38	GO:0043044	ATP-dependent chromatin remodeling

0.45	GO:0004037	allantoicase activity
0.44	GO:0008270	zinc ion binding
0.40	GO:0001026	TFIIIB-type transcription factor activity
0.40	GO:0030248	cellulose binding
0.39	GO:0003735	structural constituent of ribosome
0.39	GO:0019894	kinesin binding
0.39	GO:0005548	phospholipid transporter activity
0.38	GO:0003777	microtubule motor activity
0.38	GO:0003887	DNA-directed DNA polymerase activity
0.37	GO:0003954	NADH dehydrogenase activity

0.52	GO:0032040	small-subunit processome
0.40	GO:0043229	intracellular organelle
0.39	GO:0043228	non-membrane-bounded organelle
0.38	GO:0005604	basement membrane
0.38	GO:0044422	organelle part
0.38	GO:0005667	transcription factor complex
0.38	GO:0044444	cytoplasmic part
0.37	GO:0043227	membrane-bounded organelle
0.37	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:1902494	catalytic complex

0.45	EC:3.5.3.4	GO:0004037
0.45	KEGG:R02422	GO:0004037

tr|T1FSM9|T1FSM9_HELRO
Uncharacterized protein
Search

tr|T1FSN0|T1FSN0_HELRO
Uncharacterized protein
Search

0.61	GO:0007165	signal transduction
0.60	GO:0034220	ion transmembrane transport

0.76	GO:0005230	extracellular ligand-gated ion channel activity
0.70	GO:0099600	transmembrane receptor activity
0.65	GO:0038023	signaling receptor activity

0.30

GO:0031224

intrinsic component of membrane

tr|T1FSN1|T1FSN1_HELRO
Uncharacterized protein
Search

tr|T1FSN2|T1FSN2_HELRO
Uncharacterized protein
Search

tr|T1FSN3|T1FSN3_HELRO
Uncharacterized protein
Search

tr|T1FSN4|T1FSN4_HELRO
Uncharacterized protein
Search

tr|T1FSN5|T1FSN5_HELRO
Uncharacterized protein
Search

tr|T1FSN6|T1FSN6_HELRO
Uncharacterized protein
Search

0.37	GO:0005215	transporter activity
0.34	GO:0008201	heparin binding

0.41	GO:0031901	early endosome membrane
0.34	GO:0030667	secretory granule membrane
0.34	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0030658	transport vesicle membrane
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1FSN7|T1FSN7_HELRO
Uncharacterized protein
Search

0.39	GO:0051301	cell division
0.38	GO:0019538	protein metabolic process
0.38	GO:0055085	transmembrane transport
0.37	GO:0043043	peptide biosynthetic process
0.36	GO:0010467	gene expression
0.36	GO:0009059	macromolecule biosynthetic process
0.35	GO:0044260	cellular macromolecule metabolic process

0.52	GO:0032559	adenyl ribonucleotide binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0004176	ATP-dependent peptidase activity
0.39	GO:0008237	metallopeptidase activity
0.38	GO:0003735	structural constituent of ribosome

0.39	GO:0044444	cytoplasmic part
0.38	GO:0043226	organelle
0.38	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0031224	intrinsic component of membrane

tr|T1FSN8|T1FSN8_HELRO
Uncharacterized protein
Search

CA6

0.18	Carbonic anhydrase VI

0.69	GO:0006730	one-carbon metabolic process
0.54	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste
0.36	GO:0015701	bicarbonate transport
0.33	GO:0006414	translational elongation
0.32	GO:0005975	carbohydrate metabolic process

0.75	GO:0004089	carbonate dehydratase activity
0.61	GO:0008270	zinc ion binding
0.33	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.33	GO:0003746	translation elongation factor activity

0.48	GO:0005615	extracellular space
0.40	GO:0005829	cytosol
0.37	GO:1903561	extracellular vesicle
0.36	GO:0009570	chloroplast stroma
0.30	GO:0016021	integral component of membrane

0.75

EC:4.2.1.1

GO:0004089

tr|T1FSN9|T1FSN9_HELRO
Uncharacterized protein
Search

0.78	GO:0035023	regulation of Rho protein signal transduction
0.66	GO:0065009	regulation of molecular function
0.54	GO:0035556	intracellular signal transduction
0.53	GO:0006468	protein phosphorylation
0.51	GO:0007412	axon target recognition
0.50	GO:0045887	positive regulation of synaptic growth at neuromuscular junction
0.50	GO:0016319	mushroom body development
0.50	GO:0007480	imaginal disc-derived leg morphogenesis
0.49	GO:0048675	axon extension
0.49	GO:0046579	positive regulation of Ras protein signal transduction

0.78	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.54	GO:0004672	protein kinase activity
0.47	GO:0032559	adenyl ribonucleotide binding
0.46	GO:0008144	drug binding
0.46	GO:0035639	purine ribonucleoside triphosphate binding

0.48	GO:0030426	growth cone
0.47	GO:0030424	axon
0.47	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1FSP0|T1FSP0_HELRO
DNA helicase
Search

MCM2

0.44	DNA helicase

0.75	GO:0006270	DNA replication initiation
0.70	GO:0032392	DNA geometric change
0.54	GO:0071353	cellular response to interleukin-4
0.54	GO:0007423	sensory organ development
0.50	GO:0006334	nucleosome assembly
0.49	GO:0006915	apoptotic process
0.46	GO:0048538	thymus development
0.36	GO:0030261	chromosome condensation

0.70	GO:0003678	DNA helicase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.55	GO:0003677	DNA binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0042393	histone binding
0.47	GO:0019899	enzyme binding
0.44	GO:0003682	chromatin binding

0.79	GO:0042555	MCM complex
0.61	GO:0005634	nucleus
0.51	GO:0000808	origin recognition complex
0.47	GO:0000785	chromatin
0.47	GO:0015630	microtubule cytoskeleton
0.45	GO:0031974	membrane-enclosed lumen
0.38	GO:0005737	cytoplasm
0.34	GO:0000781	chromosome, telomeric region
0.30	GO:0031224	intrinsic component of membrane

tr|T1FSP1|T1FSP1_HELRO
Uncharacterized protein
Search

tr|T1FSP2|T1FSP2_HELRO
Uncharacterized protein
Search

0.62	GO:0006468	protein phosphorylation
0.61	GO:0061643	chemorepulsion of axon
0.56	GO:0007435	salivary gland morphogenesis
0.56	GO:0008038	neuron recognition
0.50	GO:0016204	determination of muscle attachment site
0.50	GO:0008045	motor neuron axon guidance
0.50	GO:0007482	haltere development
0.49	GO:0070983	dendrite guidance
0.49	GO:0008355	olfactory learning
0.47	GO:0007613	memory

0.62	GO:0004672	protein kinase activity
0.58	GO:0017147	Wnt-protein binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0008144	drug binding
0.51	GO:0046982	protein heterodimerization activity
0.46	GO:0019901	protein kinase binding
0.44	GO:0042803	protein homodimerization activity
0.41	GO:1904929	coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway

0.53	GO:0043235	receptor complex
0.46	GO:0030425	dendrite
0.46	GO:0030424	axon
0.43	GO:0005887	integral component of plasma membrane
0.39	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm
0.33	GO:0000428	DNA-directed RNA polymerase complex
0.33	GO:0005813	centrosome
0.33	GO:0070013	intracellular organelle lumen
0.32	GO:0043234	protein complex

0.33

EC:3.6.1.15

GO:0017111

tr|T1FSP3|T1FSP3_HELRO
Uncharacterized protein
Search

0.52	GO:0045292	mRNA cis splicing, via spliceosome
0.36	GO:0006275	regulation of DNA replication
0.36	GO:0045893	positive regulation of transcription, DNA-templated
0.36	GO:0006415	translational termination
0.35	GO:0006260	DNA replication
0.34	GO:0007165	signal transduction
0.32	GO:0005975	carbohydrate metabolic process

0.63	GO:0008270	zinc ion binding
0.55	GO:0070064	proline-rich region binding
0.51	GO:0003676	nucleic acid binding
0.33	GO:0031491	nucleosome binding
0.32	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.61	GO:0005634	nucleus
0.46	GO:0031974	membrane-enclosed lumen
0.43	GO:0030529	intracellular ribonucleoprotein complex
0.42	GO:0044446	intracellular organelle part
0.35	GO:0042025	host cell nucleus

0.32

GO:0004553

tr|T1FSP4|T1FSP4_HELRO
Uncharacterized protein
Search

tr|T1FSP5|T1FSP5_HELRO
Uncharacterized protein
Search

tr|T1FSP6|T1FSP6_HELRO
Uncharacterized protein
Search

0.43	GO:0000256	allantoin catabolic process
0.38	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA
0.37	GO:0006468	protein phosphorylation
0.36	GO:0044093	positive regulation of molecular function
0.36	GO:0006357	regulation of transcription by RNA polymerase II
0.36	GO:0018212	peptidyl-tyrosine modification
0.35	GO:0031285	regulation of sorocarp stalk cell differentiation
0.35	GO:1901261	regulation of sorocarp spore cell differentiation
0.35	GO:1903665	negative regulation of asexual reproduction
0.35	GO:0060176	regulation of aggregation involved in sorocarp development

0.44	GO:0004037	allantoicase activity
0.41	GO:0008270	zinc ion binding
0.37	GO:0017076	purine nucleotide binding
0.37	GO:0097367	carbohydrate derivative binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0004672	protein kinase activity
0.36	GO:0016874	ligase activity
0.36	GO:0003676	nucleic acid binding
0.36	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.36	GO:0008144	drug binding

0.37	GO:0005634	nucleus
0.35	GO:0000932	P-body
0.34	GO:0030014	CCR4-NOT complex
0.30	GO:0016020	membrane

0.44	EC:3.5.3.4	GO:0004037
0.44	KEGG:R02422	GO:0004037

tr|T1FSP7|T1FSP7_HELRO
Uncharacterized protein
Search

0.52	GO:0016310	phosphorylation
0.50	GO:0046328	regulation of JNK cascade
0.49	GO:0007165	signal transduction
0.47	GO:0042127	regulation of cell proliferation
0.46	GO:0006915	apoptotic process
0.44	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly
0.44	GO:2000809	positive regulation of synaptic vesicle clustering
0.43	GO:0032926	negative regulation of activin receptor signaling pathway
0.42	GO:0032835	glomerulus development
0.41	GO:0032516	positive regulation of phosphoprotein phosphatase activity

0.70	GO:0032947	protein complex scaffold activity
0.54	GO:0016301	kinase activity
0.44	GO:0070699	type II activin receptor binding
0.42	GO:0046332	SMAD binding
0.42	GO:0031697	beta-1 adrenergic receptor binding
0.40	GO:0019902	phosphatase binding
0.38	GO:0004871	signal transducer activity
0.36	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.36	GO:0042802	identical protein binding
0.35	GO:0030554	adenyl nucleotide binding

0.63	GO:0005911	cell-cell junction
0.41	GO:0030425	dendrite
0.39	GO:0005634	nucleus
0.38	GO:0014069	postsynaptic density
0.37	GO:0005770	late endosome
0.37	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0005886	plasma membrane
0.35	GO:0005829	cytosol
0.35	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.36

GO:0016773

tr|T1FSP8|T1FSP8_HELRO
Uncharacterized protein
Search

0.59	GO:0006887	exocytosis
0.54	GO:0006886	intracellular protein transport
0.51	GO:0043044	ATP-dependent chromatin remodeling
0.43	GO:0035076	ecdysone receptor-mediated signaling pathway
0.41	GO:0035053	dorsal vessel heart proper cell fate commitment
0.41	GO:0035180	larval wandering behavior
0.41	GO:0035193	larval central nervous system remodeling
0.41	GO:0007349	cellularization
0.41	GO:0035297	regulation of Malpighian tubule diameter
0.40	GO:1904799	regulation of neuron remodeling

0.61	GO:0017137	Rab GTPase binding
0.43	GO:0003677	DNA binding
0.43	GO:0004884	ecdysteroid hormone receptor activity
0.41	GO:0005496	steroid binding
0.41	GO:0001225	RNA polymerase II transcription coactivator binding
0.40	GO:0008270	zinc ion binding
0.39	GO:0070491	repressing transcription factor binding
0.39	GO:0019787	ubiquitin-like protein transferase activity
0.39	GO:0042562	hormone binding
0.39	GO:0043178	alcohol binding

0.53	GO:0016514	SWI/SNF complex
0.41	GO:0008231	repressor ecdysone receptor complex
0.41	GO:0008232	activator ecdysone receptor complex
0.40	GO:0097458	neuron part
0.39	GO:0005700	polytene chromosome
0.38	GO:0120038	plasma membrane bounded cell projection part
0.37	GO:0034707	chloride channel complex
0.35	GO:0005737	cytoplasm
0.35	GO:0005730	nucleolus
0.34	GO:0000795	synaptonemal complex

0.35

GO:0004402

tr|T1FSP9|T1FSP9_HELRO
Uncharacterized protein
Search

tr|T1FSQ0|T1FSQ0_HELRO
Uncharacterized protein
Search

tr|T1FSQ1|T1FSQ1_HELRO
Uncharacterized protein
Search

0.51	GO:0043547	positive regulation of GTPase activity
0.46	GO:1900152	negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
0.45	GO:0061412	positive regulation of transcription from RNA polymerase II promoter in response to amino acid starvation
0.45	GO:0044109	cellular alcohol catabolic process
0.45	GO:0031496	positive regulation of mating type switching
0.45	GO:0045945	positive regulation of transcription by RNA polymerase III
0.45	GO:0005987	sucrose catabolic process
0.44	GO:0006325	chromatin organization
0.44	GO:0000436	carbon catabolite activation of transcription from RNA polymerase II promoter
0.44	GO:0043488	regulation of mRNA stability

0.52	GO:0005096	GTPase activator activity
0.46	GO:0033204	ribonuclease P RNA binding
0.45	GO:0005515	protein binding
0.45	GO:0051287	NAD binding
0.45	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
0.44	GO:0008143	poly(A) binding
0.44	GO:0015616	DNA translocase activity
0.43	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.43	GO:0005545	1-phosphatidylinositol binding
0.42	GO:0008097	5S rRNA binding

0.43	GO:0005634	nucleus
0.43	GO:0070013	intracellular organelle lumen
0.42	GO:0034708	methyltransferase complex
0.42	GO:0030136	clathrin-coated vesicle
0.41	GO:0008076	voltage-gated potassium channel complex
0.40	GO:0000785	chromatin
0.39	GO:1904949	ATPase complex

0.45

EC:1.1.1

GO:0016616

tr|T1FSQ2|T1FSQ2_HELRO
Uncharacterized protein
Search

tr|T1FSQ3|T1FSQ3_HELRO
Uncharacterized protein
Search

tr|T1FSQ4|T1FSQ4_HELRO
Uncharacterized protein
Search

0.72	GO:0006913	nucleocytoplasmic transport
0.54	GO:0048026	positive regulation of mRNA splicing, via spliceosome
0.54	GO:0051292	nuclear pore complex assembly
0.49	GO:0006366	transcription by RNA polymerase II
0.48	GO:0045944	positive regulation of transcription by RNA polymerase II
0.45	GO:0000973	posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery
0.45	GO:0034398	telomere tethering at nuclear periphery
0.45	GO:0006260	DNA replication
0.43	GO:0034504	protein localization to nucleus
0.43	GO:0048484	enteric nervous system development

0.79	GO:0017056	structural constituent of nuclear pore
0.53	GO:1990841	promoter-specific chromatin binding
0.53	GO:0001105	RNA polymerase II transcription coactivator activity
0.49	GO:0003729	mRNA binding
0.45	GO:0008139	nuclear localization sequence binding
0.37	GO:0022848	acetylcholine-gated cation-selective channel activity
0.36	GO:0070011	peptidase activity, acting on L-amino acid peptides
0.36	GO:0017171	serine hydrolase activity
0.35	GO:0004888	transmembrane signaling receptor activity
0.35	GO:0005515	protein binding

0.77	GO:0005643	nuclear pore
0.54	GO:0042405	nuclear inclusion body
0.51	GO:0034399	nuclear periphery
0.50	GO:0031965	nuclear membrane
0.50	GO:0000776	kinetochore
0.50	GO:0016604	nuclear body
0.43	GO:0030529	intracellular ribonucleoprotein complex
0.37	GO:0045211	postsynaptic membrane
0.35	GO:0030054	cell junction
0.35	GO:0071339	MLL1 complex

tr|T1FSQ5|T1FSQ5_HELRO
Uncharacterized protein
Search

tr|T1FSQ6|T1FSQ6_HELRO
Uncharacterized protein
Search

tr|T1FSQ7|T1FSQ7_HELRO
Uncharacterized protein
Search

0.52	GO:0000042	protein targeting to Golgi
0.50	GO:0072659	protein localization to plasma membrane
0.37	GO:0006468	protein phosphorylation
0.37	GO:0007165	signal transduction

0.68	GO:0044325	ion channel binding
0.37	GO:0004672	protein kinase activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.49	GO:0030137	COPI-coated vesicle
0.30	GO:0016020	membrane

tr|T1FSQ8|T1FSQ8_HELRO
Uncharacterized protein
Search

0.62	GO:0006629	lipid metabolic process
0.51	GO:1901575	organic substance catabolic process
0.43	GO:0019731	antibacterial humoral response
0.41	GO:0042395	ecdysis, collagen and cuticulin-based cuticle
0.37	GO:0090407	organophosphate biosynthetic process
0.36	GO:0006796	phosphate-containing compound metabolic process
0.35	GO:0044249	cellular biosynthetic process

0.44	GO:0016787	hydrolase activity
0.42	GO:0019904	protein domain specific binding

0.41	GO:0005815	microtubule organizing center
0.40	GO:0005615	extracellular space
0.39	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.44

GO:0016787

tr|T1FSQ9|T1FSQ9_HELRO
Uncharacterized protein
Search

tr|T1FSR0|T1FSR0_HELRO
Uncharacterized protein
Search

0.61

GO:0007165

signal transduction

0.64

GO:0004871

signal transducer activity

tr|T1FSR1|T1FSR1_HELRO
Uncharacterized protein
Search

RAB43

0.67	Putative rab subfamily protein of small gtpase

0.52	GO:0035526	retrograde transport, plasma membrane to Golgi
0.49	GO:0090382	phagosome maturation
0.48	GO:0007030	Golgi organization
0.46	GO:0071346	cellular response to interferon-gamma
0.45	GO:1901998	toxin transport
0.44	GO:0019068	virion assembly
0.35	GO:0032482	Rab protein signal transduction
0.34	GO:0070507	regulation of microtubule cytoskeleton organization
0.34	GO:0043547	positive regulation of GTPase activity

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0004767	sphingomyelin phosphodiesterase activity
0.34	GO:0005515	protein binding
0.34	GO:0005096	GTPase activator activity

0.48	GO:0005794	Golgi apparatus
0.48	GO:0045335	phagocytic vesicle
0.43	GO:0005768	endosome
0.41	GO:0043025	neuronal cell body
0.40	GO:0045202	synapse
0.37	GO:0030666	endocytic vesicle membrane
0.35	GO:0070062	extracellular exosome
0.33	GO:0005874	microtubule
0.33	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.36	EC:3.1.4.12	GO:0004767
0.36	KEGG:R02541	GO:0004767

tr|T1FSR2|T1FSR2_HELRO
Uncharacterized protein
Search

0.74	GO:0007018	microtubule-based movement
0.45	GO:0099089	establishment of endoplasmic reticulum localization to postsynapse
0.44	GO:0032252	secretory granule localization
0.44	GO:0031585	regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
0.44	GO:0030050	vesicle transport along actin filament
0.44	GO:0031987	locomotion involved in locomotory behavior
0.43	GO:0032402	melanosome transport
0.43	GO:0030318	melanocyte differentiation
0.43	GO:0030073	insulin secretion
0.43	GO:0048820	hair follicle maturation

0.75	GO:0051015	actin filament binding
0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0000146	microfilament motor activity
0.43	GO:0097718	disordered domain specific binding
0.42	GO:0017137	Rab GTPase binding

0.77	GO:0016459	myosin complex
0.44	GO:0032433	filopodium tip
0.44	GO:0032593	insulin-responsive compartment
0.43	GO:0042470	melanosome
0.43	GO:0035371	microtubule plus-end
0.42	GO:0001726	ruffle
0.42	GO:0042641	actomyosin
0.42	GO:0055037	recycling endosome
0.42	GO:0001750	photoreceptor outer segment
0.42	GO:0005884	actin filament

0.35

EC:1.3.1.74

GO:0032440

tr|T1FSR3|T1FSR3_HELRO
Uncharacterized protein
Search

tr|T1FSR4|T1FSR4_HELRO
Uncharacterized protein
Search

0.30

GO:0044425

membrane part

tr|T1FSR5|T1FSR5_HELRO
Polypeptide N-acetylgalactosaminyltransferase
Search

0.65	Polypeptide N-acetylgalactosaminyltransferase

0.72	GO:0043413	macromolecule glycosylation
0.72	GO:0009101	glycoprotein biosynthetic process
0.59	GO:0006464	cellular protein modification process
0.41	GO:0009312	oligosaccharide biosynthetic process
0.33	GO:0006811	ion transport
0.33	GO:0055085	transmembrane transport

0.68	GO:0030246	carbohydrate binding
0.64	GO:0016757	transferase activity, transferring glycosyl groups
0.37	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0005215	transporter activity
0.33	GO:0004386	helicase activity
0.32	GO:0046872	metal ion binding

0.72	GO:0000139	Golgi membrane
0.34	GO:0005795	Golgi stack
0.30	GO:0031224	intrinsic component of membrane

0.64

GO:0016757

tr|T1FSR6|T1FSR6_HELRO
Uncharacterized protein
Search

tr|T1FSR7|T1FSR7_HELRO
Uncharacterized protein
Search

0.49	GO:0043401	steroid hormone mediated signaling pathway
0.47	GO:0006030	chitin metabolic process
0.47	GO:0042981	regulation of apoptotic process
0.44	GO:0000128	flocculation
0.41	GO:0006351	transcription, DNA-templated
0.41	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.41	GO:1903506	regulation of nucleic acid-templated transcription
0.41	GO:0010468	regulation of gene expression

0.47

GO:0008061

chitin binding

0.43	GO:0005576	extracellular region
0.43	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|T1FSR8|T1FSR8_HELRO
Poly [ADP-ribose] polymerase
Search

0.28	Poly [ADP-ribose] polymerase

0.42	GO:0006468	protein phosphorylation
0.38	GO:0016070	RNA metabolic process
0.38	GO:1903506	regulation of nucleic acid-templated transcription
0.38	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.38	GO:0010468	regulation of gene expression
0.38	GO:0010467	gene expression
0.37	GO:0034654	nucleobase-containing compound biosynthetic process
0.36	GO:0009059	macromolecule biosynthetic process
0.36	GO:0060285	cilium-dependent cell motility
0.36	GO:0070286	axonemal dynein complex assembly

0.71	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.42	GO:0004672	protein kinase activity
0.41	GO:0003677	DNA binding
0.39	GO:0030554	adenyl nucleotide binding
0.38	GO:0097367	carbohydrate derivative binding
0.38	GO:0008144	drug binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0050825	ice binding
0.37	GO:0003723	RNA binding
0.36	GO:0046332	SMAD binding

0.41	GO:0005634	nucleus
0.38	GO:0036464	cytoplasmic ribonucleoprotein granule
0.36	GO:0042788	polysomal ribosome
0.36	GO:0030015	CCR4-NOT core complex
0.36	GO:0031974	membrane-enclosed lumen
0.35	GO:0005829	cytosol
0.34	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.71

GO:0003950

tr|T1FSR9|T1FSR9_HELRO
Poly [ADP-ribose] polymerase
Search

0.30	Poly [ADP-ribose] polymerase

0.45	GO:0006915	apoptotic process
0.40	GO:0006508	proteolysis

0.82	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.45	GO:0004197	cysteine-type endopeptidase activity
0.33	GO:0003676	nucleic acid binding

0.82

GO:0003950

tr|T1FSS0|T1FSS0_HELRO
Uncharacterized protein
Search

tr|T1FSS1|T1FSS1_HELRO
Uncharacterized protein
Search

0.48	GO:0007479	leg disc proximal/distal pattern formation
0.48	GO:0008057	eye pigment granule organization
0.48	GO:0007091	metaphase/anaphase transition of mitotic cell cycle
0.47	GO:0008052	sensory organ boundary specification
0.47	GO:0007455	eye-antennal disc morphogenesis
0.47	GO:0008407	chaeta morphogenesis
0.46	GO:0010458	exit from mitosis
0.46	GO:0001751	compound eye photoreceptor cell differentiation
0.46	GO:0006357	regulation of transcription by RNA polymerase II
0.45	GO:0031145	anaphase-promoting complex-dependent catabolic process

0.46	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.43	GO:0008536	Ran GTPase binding
0.43	GO:0044212	transcription regulatory region DNA binding
0.42	GO:0042802	identical protein binding
0.42	GO:0004842	ubiquitin-protein transferase activity
0.42	GO:0003682	chromatin binding
0.40	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.40	GO:0043565	sequence-specific DNA binding
0.40	GO:0008168	methyltransferase activity
0.39	GO:0046872	metal ion binding

0.49	GO:0005634	nucleus
0.43	GO:0031461	cullin-RING ubiquitin ligase complex
0.42	GO:0000785	chromatin
0.40	GO:0031974	membrane-enclosed lumen
0.40	GO:1904949	ATPase complex
0.30	GO:0016020	membrane

0.40	EC:3.2.1	GO:0004553
0.42	KEGG:R03876	GO:0004842

tr|T1FSS2|T1FSS2_HELRO
Uncharacterized protein
Search

tr|T1FSS3|T1FSS3_HELRO
Uncharacterized protein
Search

E2F4

0.84	E2F transcription factor 4

0.68	GO:0000278	mitotic cell cycle
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0006884	cell volume homeostasis
0.54	GO:0044843	cell cycle G1/S phase transition
0.53	GO:0002064	epithelial cell development
0.52	GO:0008015	blood circulation
0.52	GO:0060271	cilium assembly

0.67	GO:0046983	protein dimerization activity
0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:1990841	promoter-specific chromatin binding
0.55	GO:0003677	DNA binding
0.51	GO:0019904	protein domain specific binding
0.50	GO:0001067	regulatory region nucleic acid binding
0.49	GO:0008134	transcription factor binding
0.36	GO:0047485	protein N-terminus binding
0.36	GO:0008022	protein C-terminus binding
0.30	GO:0003824	catalytic activity

0.75	GO:0005667	transcription factor complex
0.61	GO:0005634	nucleus
0.49	GO:0000785	chromatin
0.46	GO:0043233	organelle lumen
0.32	GO:0005737	cytoplasm

tr|T1FSS4|T1FSS4_HELRO
Uncharacterized protein
Search

0.67	GO:0016925	protein sumoylation
0.53	GO:1990683	DNA double-strand break attachment to nuclear envelope
0.50	GO:0031397	negative regulation of protein ubiquitination
0.45	GO:0007059	chromosome segregation
0.40	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.39	GO:0016310	phosphorylation

0.68	GO:0019789	SUMO transferase activity
0.54	GO:0008270	zinc ion binding
0.44	GO:0004386	helicase activity
0.43	GO:0016874	ligase activity
0.40	GO:0004518	nuclease activity
0.40	GO:0016301	kinase activity
0.38	GO:0032559	adenyl ribonucleotide binding
0.38	GO:0008144	drug binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0016773	phosphotransferase activity, alcohol group as acceptor

0.49	GO:0005940	septin ring
0.46	GO:0000790	nuclear chromatin
0.41	GO:0005935	cellular bud neck
0.30	GO:0016020	membrane

0.43

GO:0016874

tr|T1FSS5|T1FSS5_HELRO
Uncharacterized protein
Search

0.11	collagen alpha-1(XXIII) chain-like

0.50	GO:0030198	extracellular matrix organization
0.47	GO:0035989	tendon development
0.47	GO:0007275	multicellular organism development
0.46	GO:0007155	cell adhesion
0.46	GO:0048729	tissue morphogenesis
0.46	GO:0045112	integrin biosynthetic process
0.45	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.45	GO:1903225	negative regulation of endodermal cell differentiation
0.45	GO:0032963	collagen metabolic process
0.44	GO:0052548	regulation of endopeptidase activity

0.69	GO:0005201	extracellular matrix structural constituent
0.48	GO:0048407	platelet-derived growth factor binding
0.43	GO:0043394	proteoglycan binding
0.43	GO:0004867	serine-type endopeptidase inhibitor activity
0.43	GO:0008201	heparin binding
0.41	GO:0042302	structural constituent of cuticle
0.39	GO:0005178	integrin binding
0.36	GO:0042802	identical protein binding
0.35	GO:0008191	metalloendopeptidase inhibitor activity
0.33	GO:0030246	carbohydrate binding

0.70	GO:0005581	collagen trimer
0.59	GO:0044420	extracellular matrix component
0.56	GO:0005578	proteinaceous extracellular matrix
0.46	GO:0005615	extracellular space
0.46	GO:0099080	supramolecular complex
0.37	GO:0005783	endoplasmic reticulum
0.36	GO:1903561	extracellular vesicle
0.35	GO:0031594	neuromuscular junction
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part

tr|T1FSS6|T1FSS6_HELRO
Uncharacterized protein
Search

tr|T1FSS7|T1FSS7_HELRO
Uncharacterized protein
Search

0.63	Cyclin D binding myb-like transcription factor 1

0.43	GO:0006357	regulation of transcription by RNA polymerase II
0.42	GO:0030154	cell differentiation
0.38	GO:0006366	transcription by RNA polymerase II
0.38	GO:0045893	positive regulation of transcription, DNA-templated
0.36	GO:0007049	cell cycle
0.33	GO:0043043	peptide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process

0.54	GO:0003677	DNA binding
0.46	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting
0.45	GO:0001067	regulatory region nucleic acid binding
0.44	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.33	GO:0016746	transferase activity, transferring acyl groups
0.33	GO:0003735	structural constituent of ribosome

0.47	GO:0005654	nucleoplasm
0.47	GO:0005829	cytosol
0.33	GO:0005840	ribosome

0.33

EC:2.3

GO:0016746

tr|T1FSS8|T1FSS8_HELRO
Uncharacterized protein
Search

tr|T1FSS9|T1FSS9_HELRO
Uncharacterized protein
Search

0.88	Phosphorylase phosphatase

0.76	GO:0043666	regulation of phosphoprotein phosphatase activity
0.67	GO:0006461	protein complex assembly
0.62	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
0.61	GO:0051232	meiotic spindle elongation
0.59	GO:1903538	regulation of meiotic cell cycle process involved in oocyte maturation
0.58	GO:0051306	mitotic sister chromatid separation
0.57	GO:0051754	meiotic sister chromatid cohesion, centromeric
0.56	GO:0070262	peptidyl-serine dephosphorylation
0.56	GO:0007143	female meiotic nuclear division
0.45	GO:0060561	apoptotic process involved in morphogenesis

0.77	GO:0019888	protein phosphatase regulator activity
0.63	GO:1990405	protein antigen binding
0.53	GO:0046982	protein heterodimerization activity
0.51	GO:0004722	protein serine/threonine phosphatase activity
0.39	GO:0050196	[phosphorylase] phosphatase activity
0.36	GO:0008408	3'-5' exonuclease activity
0.35	GO:0003676	nucleic acid binding
0.34	GO:0046872	metal ion binding

0.57	GO:0000159	protein phosphatase type 2A complex
0.56	GO:0000775	chromosome, centromeric region
0.48	GO:0005829	cytosol
0.44	GO:0016328	lateral plasma membrane
0.43	GO:0030425	dendrite
0.42	GO:0098857	membrane microdomain
0.39	GO:0070062	extracellular exosome
0.35	GO:0015630	microtubule cytoskeleton
0.34	GO:0005634	nucleus
0.34	GO:0005739	mitochondrion

0.39

EC:3.1.3.17

GO:0050196

tr|T1FST0|T1FST0_HELRO
Uncharacterized protein
Search

tr|T1FST1|T1FST1_HELRO
DNA polymerase epsilon subunit
Search

POLE2

0.83	DNA polymerase epsilon subunit

0.67	GO:0071897	DNA biosynthetic process
0.67	GO:0006261	DNA-dependent DNA replication
0.48	GO:0006301	postreplication repair
0.42	GO:0051781	positive regulation of cell division
0.42	GO:0009793	embryo development ending in seed dormancy
0.34	GO:0000082	G1/S transition of mitotic cell cycle
0.34	GO:0000723	telomere maintenance
0.33	GO:0060285	cilium-dependent cell motility
0.33	GO:0019725	cellular homeostasis
0.33	GO:0070286	axonemal dynein complex assembly

0.71	GO:0003887	DNA-directed DNA polymerase activity
0.55	GO:0003677	DNA binding
0.43	GO:0070182	DNA polymerase binding
0.32	GO:0020037	heme binding
0.32	GO:0005506	iron ion binding
0.32	GO:0016491	oxidoreductase activity

0.80	GO:0008622	epsilon DNA polymerase complex
0.48	GO:0016604	nuclear body
0.34	GO:0005680	anaphase-promoting complex
0.31	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.71

GO:0003887

tr|T1FST2|T1FST2_HELRO
Uncharacterized protein
Search

0.58	GO:0046329	negative regulation of JNK cascade
0.56	GO:0010212	response to ionizing radiation
0.56	GO:0048728	proboscis development
0.55	GO:0046528	imaginal disc fusion
0.54	GO:0045786	negative regulation of cell cycle
0.52	GO:0009967	positive regulation of signal transduction
0.52	GO:1902806	regulation of cell cycle G1/S phase transition
0.52	GO:0008340	determination of adult lifespan
0.51	GO:0036297	interstrand cross-link repair
0.51	GO:0001666	response to hypoxia

0.50	GO:0000403	Y-form DNA binding
0.47	GO:0018024	histone-lysine N-methyltransferase activity
0.47	GO:0070412	R-SMAD binding
0.46	GO:0000400	four-way junction DNA binding
0.46	GO:0047485	protein N-terminus binding
0.46	GO:0044212	transcription regulatory region DNA binding
0.45	GO:0003690	double-stranded DNA binding
0.45	GO:0030674	protein binding, bridging
0.43	GO:0003682	chromatin binding
0.33	GO:0043565	sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.54	GO:0034708	methyltransferase complex
0.49	GO:0070013	intracellular organelle lumen
0.46	GO:0097610	cell surface furrow
0.45	GO:0032155	cell division site part
0.45	GO:0000785	chromatin
0.41	GO:0005829	cytosol
0.39	GO:0043234	protein complex
0.36	GO:0000781	chromosome, telomeric region
0.35	GO:1905369	endopeptidase complex

0.47

GO:0018024

tr|T1FST3|T1FST3_HELRO
Uncharacterized protein
Search

0.10	Retroviral integration site protein Fli-1-like protein

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:2000504	positive regulation of blood vessel remodeling
0.54	GO:0003199	endocardial cushion to mesenchymal transition involved in heart valve formation
0.52	GO:0003197	endocardial cushion development
0.48	GO:0016477	cell migration
0.48	GO:1902680	positive regulation of RNA biosynthetic process
0.38	GO:0060217	hemangioblast cell differentiation
0.37	GO:0071542	dopaminergic neuron differentiation

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.49	GO:0001012	RNA polymerase II regulatory region DNA binding
0.48	GO:0003682	chromatin binding
0.47	GO:0003690	double-stranded DNA binding
0.34	GO:0035326	enhancer binding
0.34	GO:0005515	protein binding
0.33	GO:0004871	signal transducer activity

0.61	GO:0005634	nucleus
0.42	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0005829	cytosol
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0044446	intracellular organelle part

tr|T1FST4|T1FST4_HELRO
Uncharacterized protein
Search

0.68	GO:0045087	innate immune response
0.55	GO:0007165	signal transduction
0.46	GO:2001222	regulation of neuron migration
0.43	GO:0021828	gonadotrophin-releasing hormone neuronal migration to the hypothalamus
0.42	GO:0010033	response to organic substance
0.41	GO:0046426	negative regulation of JAK-STAT cascade
0.40	GO:0006469	negative regulation of protein kinase activity
0.39	GO:0009719	response to endogenous stimulus
0.38	GO:0042730	fibrinolysis
0.37	GO:0070887	cellular response to chemical stimulus

0.40	GO:0004860	protein kinase inhibitor activity
0.35	GO:0005525	GTP binding
0.35	GO:0005515	protein binding
0.30	GO:0003824	catalytic activity

0.40	GO:0005576	extracellular region
0.38	GO:0031362	anchored component of external side of plasma membrane
0.37	GO:0008021	synaptic vesicle
0.30	GO:0016021	integral component of membrane

tr|T1FST5|T1FST5_HELRO
Uncharacterized protein
Search

UXS1

0.85	UDP-glucuronic acid decarboxylase 1

0.50	GO:0051262	protein tetramerization
0.42	GO:0030206	chondroitin sulfate biosynthetic process
0.42	GO:0015012	heparan sulfate proteoglycan biosynthetic process
0.42	GO:0033320	UDP-D-xylose biosynthetic process
0.41	GO:0051216	cartilage development
0.41	GO:0001503	ossification
0.41	GO:0030198	extracellular matrix organization

0.80	GO:0048040	UDP-glucuronate decarboxylase activity
0.50	GO:0070403	NAD+ binding
0.48	GO:0042803	protein homodimerization activity
0.33	GO:0003723	RNA binding

0.40	GO:0005739	mitochondrion
0.39	GO:0032580	Golgi cisterna membrane
0.36	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.80	EC:4.1.1.35	GO:0048040
0.80	KEGG:R01384	GO:0048040

tr|T1FST6|T1FST6_HELRO
Uncharacterized protein
Search

0.56	GO:0033169	histone H3-K9 demethylation
0.55	GO:0032259	methylation
0.53	GO:0046293	formaldehyde biosynthetic process
0.52	GO:0007290	spermatid nucleus elongation
0.52	GO:0051573	negative regulation of histone H3-K9 methylation
0.51	GO:2000036	regulation of stem cell population maintenance
0.51	GO:0061647	histone H3-K9 modification
0.50	GO:2000736	regulation of stem cell differentiation
0.50	GO:0030521	androgen receptor signaling pathway
0.50	GO:1990830	cellular response to leukemia inhibitory factor

0.56	GO:0032454	histone demethylase activity (H3-K9 specific)
0.53	GO:0008168	methyltransferase activity
0.51	GO:0000976	transcription regulatory region sequence-specific DNA binding
0.50	GO:0050681	androgen receptor binding
0.49	GO:0001047	core promoter binding
0.48	GO:0031490	chromatin DNA binding
0.47	GO:0001012	RNA polymerase II regulatory region DNA binding
0.41	GO:0005506	iron ion binding
0.41	GO:0003700	DNA binding transcription factor activity
0.36	GO:0051213	dioxygenase activity

0.50	GO:0005654	nucleoplasm
0.44	GO:0000785	chromatin
0.37	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.53

GO:0008168

tr|T1FST7|T1FST7_HELRO
Uncharacterized protein
Search

0.40	GO:0065007	biological regulation
0.39	GO:0006397	mRNA processing
0.38	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic
0.38	GO:0036360	sorocarp stalk morphogenesis
0.38	GO:0060429	epithelium development
0.38	GO:0043412	macromolecule modification
0.38	GO:0044671	sorocarp spore cell differentiation
0.38	GO:0010876	lipid localization
0.38	GO:0006928	movement of cell or subcellular component
0.37	GO:0035017	cuticle pattern formation

0.43	GO:0003723	RNA binding
0.40	GO:0005515	protein binding
0.39	GO:0017111	nucleoside-triphosphatase activity
0.39	GO:0004534	5'-3' exoribonuclease activity
0.39	GO:0046872	metal ion binding
0.38	GO:0003677	DNA binding
0.38	GO:0003700	DNA binding transcription factor activity
0.37	GO:0017076	purine nucleotide binding
0.37	GO:0097367	carbohydrate derivative binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding

0.43	GO:0005634	nucleus
0.37	GO:0045180	basal cortex
0.36	GO:0005912	adherens junction
0.36	GO:0005813	centrosome
0.36	GO:0009986	cell surface
0.36	GO:0005911	cell-cell junction
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.39

EC:3.6.1.15

GO:0017111

tr|T1FST8|T1FST8_HELRO
Uncharacterized protein
Search

PPP2R3C

0.95	Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma

0.82	GO:0045579	positive regulation of B cell differentiation
0.81	GO:0001782	B cell homeostasis
0.80	GO:0043029	T cell homeostasis
0.75	GO:0051900	regulation of mitochondrial depolarization
0.74	GO:0002759	regulation of antimicrobial humoral response
0.73	GO:0048536	spleen development
0.67	GO:0032147	activation of protein kinase activity
0.62	GO:0030865	cortical cytoskeleton organization
0.58	GO:0000226	microtubule cytoskeleton organization

0.50	GO:0005509	calcium ion binding
0.37	GO:0005515	protein binding

0.72	GO:0005813	centrosome
0.61	GO:0005794	Golgi apparatus
0.59	GO:0005829	cytosol
0.58	GO:0005819	spindle
0.54	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

tr|T1FST9|T1FST9_HELRO
Uncharacterized protein
Search

LET-2

0.65	C-terminal tandem repeated domain in type 4 procollagen

0.39	GO:0030198	extracellular matrix organization
0.39	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.39	GO:0048731	system development
0.38	GO:0009653	anatomical structure morphogenesis
0.38	GO:0071230	cellular response to amino acid stimulus
0.38	GO:0060729	intestinal epithelial structure maintenance
0.37	GO:0035295	tube development
0.37	GO:0048468	cell development
0.37	GO:0014706	striated muscle tissue development
0.37	GO:0061061	muscle structure development

0.81	GO:0005201	extracellular matrix structural constituent
0.34	GO:0070547	L-tyrosine aminotransferase activity
0.34	GO:0048407	platelet-derived growth factor binding
0.34	GO:0051431	corticotropin-releasing hormone receptor 2 binding
0.33	GO:0003777	microtubule motor activity
0.33	GO:0008017	microtubule binding
0.33	GO:0003779	actin binding
0.33	GO:0005179	hormone activity
0.33	GO:0004867	serine-type endopeptidase inhibitor activity
0.33	GO:0070279	vitamin B6 binding

0.81	GO:0005604	basement membrane
0.78	GO:0005581	collagen trimer
0.41	GO:0098645	collagen network
0.34	GO:0031594	neuromuscular junction
0.34	GO:0005615	extracellular space
0.34	GO:0016459	myosin complex
0.30	GO:0016020	membrane

tr|T1FSU0|T1FSU0_HELRO
Uncharacterized protein
Search

tr|T1FSU1|T1FSU1_HELRO
Uncharacterized protein
Search

0.41	GO:0043547	positive regulation of GTPase activity
0.39	GO:0036211	protein modification process
0.38	GO:0044267	cellular protein metabolic process
0.37	GO:0006325	chromatin organization
0.37	GO:0016310	phosphorylation
0.37	GO:0060255	regulation of macromolecule metabolic process
0.36	GO:0031323	regulation of cellular metabolic process
0.36	GO:0051171	regulation of nitrogen compound metabolic process
0.36	GO:0080090	regulation of primary metabolic process
0.36	GO:0006351	transcription, DNA-templated

0.68	GO:0045735	nutrient reservoir activity
0.42	GO:0005096	GTPase activator activity
0.39	GO:0004672	protein kinase activity
0.38	GO:0003682	chromatin binding
0.37	GO:0001085	RNA polymerase II transcription factor binding
0.37	GO:0030554	adenyl nucleotide binding
0.37	GO:0140110	transcription regulator activity
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0032555	purine ribonucleotide binding

0.39	GO:0005634	nucleus
0.38	GO:0070013	intracellular organelle lumen
0.38	GO:0031248	protein acetyltransferase complex
0.38	GO:0043234	protein complex
0.37	GO:0044446	intracellular organelle part
0.36	GO:0000428	DNA-directed RNA polymerase complex
0.36	GO:1905368	peptidase complex
0.36	GO:0012505	endomembrane system
0.36	GO:0030134	COPII-coated ER to Golgi transport vesicle
0.35	GO:0012506	vesicle membrane

0.35

GO:0004402

tr|T1FSU2|T1FSU2_HELRO
Uncharacterized protein
Search

0.42	GO:0006357	regulation of transcription by RNA polymerase II
0.41	GO:0006413	translational initiation
0.40	GO:0045893	positive regulation of transcription, DNA-templated
0.40	GO:0051276	chromosome organization
0.40	GO:0043412	macromolecule modification
0.39	GO:0048337	positive regulation of mesodermal cell fate specification
0.39	GO:0003006	developmental process involved in reproduction
0.39	GO:1901537	positive regulation of DNA demethylation
0.38	GO:0007166	cell surface receptor signaling pathway
0.38	GO:0040018	positive regulation of multicellular organism growth

0.56	GO:0045735	nutrient reservoir activity
0.45	GO:0003712	transcription cofactor activity
0.43	GO:0008270	zinc ion binding
0.42	GO:0003676	nucleic acid binding
0.41	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.40	GO:0140096	catalytic activity, acting on a protein
0.39	GO:0016788	hydrolase activity, acting on ester bonds
0.38	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.38	GO:0035516	oxidative DNA demethylase activity
0.38	GO:0016301	kinase activity

0.45	GO:0005634	nucleus
0.42	GO:0070013	intracellular organelle lumen
0.39	GO:0044446	intracellular organelle part
0.39	GO:1990234	transferase complex
0.38	GO:0043234	protein complex
0.38	GO:1905368	peptidase complex
0.30	GO:0016020	membrane

0.39

EC:3.1

GO:0016788

tr|T1FSU3|T1FSU3_HELRO
Galectin
Search

0.31

Galectin

0.43	GO:0060255	regulation of macromolecule metabolic process
0.43	GO:0031326	regulation of cellular biosynthetic process
0.43	GO:0051171	regulation of nitrogen compound metabolic process
0.43	GO:0080090	regulation of primary metabolic process
0.42	GO:0016070	RNA metabolic process
0.41	GO:0000075	cell cycle checkpoint
0.41	GO:0010467	gene expression
0.41	GO:1901990	regulation of mitotic cell cycle phase transition
0.41	GO:0032501	multicellular organismal process
0.40	GO:2000816	negative regulation of mitotic sister chromatid separation

0.49	GO:0030246	carbohydrate binding
0.42	GO:0003676	nucleic acid binding
0.41	GO:0140110	transcription regulator activity
0.40	GO:0008270	zinc ion binding
0.40	GO:0005515	protein binding
0.38	GO:0004672	protein kinase activity
0.37	GO:0050825	ice binding
0.37	GO:0003777	microtubule motor activity
0.37	GO:0030554	adenyl nucleotide binding
0.37	GO:0032555	purine ribonucleotide binding

0.47	GO:0005634	nucleus
0.41	GO:0043234	protein complex
0.41	GO:0070013	intracellular organelle lumen
0.40	GO:1990234	transferase complex
0.39	GO:0044446	intracellular organelle part
0.39	GO:0015629	actin cytoskeleton
0.38	GO:0097458	neuron part
0.36	GO:0030175	filopodium
0.36	GO:0005700	polytene chromosome
0.36	GO:0000932	P-body

0.36	EC:1.2.1.27	GO:0004491
0.35	KEGG:R03876	GO:0004842

tr|T1FSU4|T1FSU4_HELRO
Uncharacterized protein
Search

tr|T1FSU5|T1FSU5_HELRO
Uncharacterized protein
Search

tr|T1FSU6|T1FSU6_HELRO
Uncharacterized protein
Search

MIB1

0.90	Mindbomb E3 ubiquitin protein ligase 1

0.73	GO:0016567	protein ubiquitination
0.49	GO:0007219	Notch signaling pathway
0.48	GO:0001756	somitogenesis
0.47	GO:0001947	heart looping
0.47	GO:0021915	neural tube development
0.47	GO:0016331	morphogenesis of embryonic epithelium
0.47	GO:0045807	positive regulation of endocytosis
0.47	GO:0072175	epithelial tube formation
0.47	GO:0045665	negative regulation of neuron differentiation
0.46	GO:0001568	blood vessel development

0.74	GO:0004842	ubiquitin-protein transferase activity
0.63	GO:0008270	zinc ion binding
0.54	GO:0016874	ligase activity
0.35	GO:0005515	protein binding

0.45	GO:0005813	centrosome
0.44	GO:0031410	cytoplasmic vesicle
0.37	GO:0014069	postsynaptic density
0.34	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0000151	ubiquitin ligase complex
0.34	GO:0005886	plasma membrane
0.33	GO:0005829	cytosol
0.33	GO:0043234	protein complex

0.54	EC:6	GO:0016874
0.74	KEGG:R03876	GO:0004842

tr|T1FSU7|T1FSU7_HELRO
Uncharacterized protein
Search

tr|T1FSU8|T1FSU8_HELRO
Uncharacterized protein
Search

0.56	GO:0006468	protein phosphorylation
0.45	GO:0048599	oocyte development
0.44	GO:0007050	cell cycle arrest
0.44	GO:0032008	positive regulation of TOR signaling
0.43	GO:0080090	regulation of primary metabolic process
0.43	GO:0060255	regulation of macromolecule metabolic process
0.43	GO:0031323	regulation of cellular metabolic process
0.43	GO:0051171	regulation of nitrogen compound metabolic process
0.42	GO:0016567	protein ubiquitination
0.42	GO:0009893	positive regulation of metabolic process

0.56	GO:0004672	protein kinase activity
0.49	GO:0032559	adenyl ribonucleotide binding
0.49	GO:0008144	drug binding
0.49	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0003700	DNA binding transcription factor activity
0.42	GO:0004842	ubiquitin-protein transferase activity
0.38	GO:0046872	metal ion binding
0.38	GO:0018024	histone-lysine N-methyltransferase activity
0.37	GO:0004871	signal transducer activity
0.36	GO:0001085	RNA polymerase II transcription factor binding

0.35	GO:0005622	intracellular
0.34	GO:0048786	presynaptic active zone
0.33	GO:0043234	protein complex
0.33	GO:0043227	membrane-bounded organelle
0.30	GO:0016020	membrane

0.38	EC:2.1.1.43	GO:0018024
0.42	KEGG:R03876	GO:0004842

tr|T1FSU9|T1FSU9_HELRO
Uncharacterized protein
Search

0.85	GO:0090043	regulation of tubulin deacetylation
0.83	GO:0043966	histone H3 acetylation
0.82	GO:0031063	regulation of histone deacetylation
0.74	GO:0031647	regulation of protein stability
0.70	GO:0000278	mitotic cell cycle
0.69	GO:0043967	histone H4 acetylation
0.69	GO:0045893	positive regulation of transcription, DNA-templated
0.68	GO:0001932	regulation of protein phosphorylation
0.59	GO:0006357	regulation of transcription by RNA polymerase II
0.36	GO:0006351	transcription, DNA-templated

0.83	GO:0016922	ligand-dependent nuclear receptor binding
0.80	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.78	GO:0004402	histone acetyltransferase activity
0.72	GO:0019904	protein domain specific binding
0.39	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.37	GO:0008270	zinc ion binding
0.35	GO:0003677	DNA binding

0.83	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex
0.83	GO:0030914	STAGA complex
0.83	GO:0033276	transcription factor TFTC complex
0.75	GO:0072686	mitotic spindle
0.66	GO:0000124	SAGA complex
0.30	GO:0016020	membrane

0.78

GO:0004402

tr|T1FSV0|T1FSV0_HELRO
Uncharacterized protein
Search

tr|T1FSV1|T1FSV1_HELRO
Uncharacterized protein
Search

0.70	GO:0010738	regulation of protein kinase A signaling
0.69	GO:0035329	hippo signaling
0.61	GO:0016567	protein ubiquitination
0.38	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.34	GO:0000398	mRNA splicing, via spliceosome

0.62	GO:0004842	ubiquitin-protein transferase activity
0.47	GO:0016874	ligase activity
0.47	GO:0008270	zinc ion binding
0.42	GO:0061659	ubiquitin-like protein ligase activity
0.33	GO:0003723	RNA binding

0.41	GO:0005622	intracellular
0.33	GO:0043234	protein complex
0.33	GO:0044422	organelle part
0.33	GO:0043227	membrane-bounded organelle
0.30	GO:0016020	membrane

0.47	EC:6	GO:0016874
0.62	KEGG:R03876	GO:0004842

tr|T1FSV2|T1FSV2_HELRO
Uncharacterized protein
Search

0.77	GO:0032012	regulation of ARF protein signal transduction
0.63	GO:0065009	regulation of molecular function
0.35	GO:0018193	peptidyl-amino acid modification
0.35	GO:0016570	histone modification
0.35	GO:0060255	regulation of macromolecule metabolic process
0.35	GO:0048102	autophagic cell death
0.35	GO:0006475	internal protein amino acid acetylation
0.35	GO:0031326	regulation of cellular biosynthetic process
0.35	GO:0019219	regulation of nucleobase-containing compound metabolic process
0.34	GO:0006351	transcription, DNA-templated

0.77	GO:0005086	ARF guanyl-nucleotide exchange factor activity
0.58	GO:0005543	phospholipid binding
0.36	GO:0008270	zinc ion binding
0.36	GO:0003676	nucleic acid binding
0.35	GO:0003700	DNA binding transcription factor activity
0.35	GO:0004402	histone acetyltransferase activity
0.35	GO:0140096	catalytic activity, acting on a protein
0.34	GO:0004087	carbamoyl-phosphate synthase (ammonia) activity
0.34	GO:0003682	chromatin binding
0.34	GO:0046983	protein dimerization activity

0.36	GO:0005634	nucleus
0.36	GO:0005667	transcription factor complex
0.35	GO:1990234	transferase complex
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0044446	intracellular organelle part
0.33	GO:0005615	extracellular space
0.33	GO:0015630	microtubule cytoskeleton
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.35	EC:2.3.1.48	GO:0004402
0.34	KEGG:R00149	GO:0004087

tr|T1FSV3|T1FSV3_HELRO
Uncharacterized protein
Search

COL2A1

0.77	Type IIA procollagen

0.57	GO:0030199	collagen fibril organization
0.54	GO:0048706	embryonic skeletal system development
0.54	GO:0007605	sensory perception of sound
0.53	GO:0048705	skeletal system morphogenesis
0.53	GO:0051216	cartilage development
0.52	GO:0072359	circulatory system development
0.52	GO:0036075	replacement ossification
0.52	GO:0007601	visual perception
0.51	GO:0098743	cell aggregation
0.50	GO:0048568	embryonic organ development

0.76	GO:0005201	extracellular matrix structural constituent
0.55	GO:0048407	platelet-derived growth factor binding
0.48	GO:0042289	MHC class II protein binding
0.48	GO:0042802	identical protein binding
0.46	GO:0002020	protease binding
0.38	GO:0030674	protein binding, bridging
0.38	GO:0046332	SMAD binding
0.37	GO:0042302	structural constituent of cuticle
0.34	GO:0046872	metal ion binding
0.34	GO:0004867	serine-type endopeptidase inhibitor activity

0.68	GO:0005581	collagen trimer
0.59	GO:0098643	banded collagen fibril
0.51	GO:0005615	extracellular space
0.49	GO:0005604	basement membrane
0.38	GO:0005737	cytoplasm
0.37	GO:0012505	endomembrane system
0.36	GO:0098645	collagen network
0.35	GO:0043231	intracellular membrane-bounded organelle
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0019867	outer membrane

0.32

GO:0004402

tr|T1FSV4|T1FSV4_HELRO
Uncharacterized protein
Search

0.55	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.50	GO:0045948	positive regulation of translational initiation
0.46	GO:0006413	translational initiation
0.35	GO:0006400	tRNA modification

0.67	GO:0004386	helicase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0042802	identical protein binding
0.50	GO:0140098	catalytic activity, acting on RNA
0.50	GO:0008186	RNA-dependent ATPase activity
0.47	GO:0003676	nucleic acid binding
0.35	GO:0051539	4 iron, 4 sulfur cluster binding
0.33	GO:0016740	transferase activity

0.51	GO:0005730	nucleolus
0.38	GO:0005737	cytoplasm
0.38	GO:0005681	spliceosomal complex

0.33

GO:0016740

tr|T1FSV5|T1FSV5_HELRO
Uncharacterized protein
Search

0.63	GO:0006468	protein phosphorylation
0.50	GO:0075071	autophagy involved in symbiotic interaction
0.46	GO:0031175	neuron projection development
0.45	GO:0048667	cell morphogenesis involved in neuron differentiation
0.45	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.45	GO:0048588	developmental cell growth
0.45	GO:0060560	developmental growth involved in morphogenesis
0.43	GO:0048671	negative regulation of collateral sprouting
0.41	GO:0031667	response to nutrient levels
0.40	GO:0018209	peptidyl-serine modification

0.64	GO:0004672	protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0017137	Rab GTPase binding
0.38	GO:0032403	protein complex binding
0.38	GO:0042802	identical protein binding
0.36	GO:0005509	calcium ion binding
0.35	GO:0004871	signal transducer activity

0.47	GO:0034045	phagophore assembly site membrane
0.42	GO:0005776	autophagosome
0.41	GO:0097629	extrinsic component of omegasome membrane
0.41	GO:1990316	Atg1/ULK1 kinase complex
0.40	GO:0000306	extrinsic component of vacuolar membrane
0.40	GO:0032045	guanyl-nucleotide exchange factor complex
0.37	GO:0005829	cytosol
0.34	GO:0030659	cytoplasmic vesicle membrane
0.34	GO:0016592	mediator complex
0.34	GO:0005964	phosphorylase kinase complex

0.34

EC:2.7.3

GO:0016775

tr|T1FSV6|T1FSV6_HELRO
Uncharacterized protein
Search

0.60	GO:0032259	methylation
0.41	GO:0042051	compound eye photoreceptor development
0.37	GO:0022900	electron transport chain

0.61	GO:0008168	methyltransferase activity
0.37	GO:0020037	heme binding
0.37	GO:0046872	metal ion binding
0.37	GO:0009055	electron transfer activity

0.36	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

0.61

GO:0008168

tr|T1FSV7|T1FSV7_HELRO
Uncharacterized protein
Search

0.43	GO:0016567	protein ubiquitination
0.43	GO:1903506	regulation of nucleic acid-templated transcription
0.43	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.42	GO:0010468	regulation of gene expression
0.38	GO:0007018	microtubule-based movement
0.38	GO:0030488	tRNA methylation
0.37	GO:0006366	transcription by RNA polymerase II
0.36	GO:0097466	ubiquitin-dependent glycoprotein ERAD pathway
0.36	GO:0006491	N-glycan processing
0.35	GO:0030968	endoplasmic reticulum unfolded protein response

0.44	GO:0003700	DNA binding transcription factor activity
0.43	GO:0004842	ubiquitin-protein transferase activity
0.39	GO:0003777	microtubule motor activity
0.37	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity
0.37	GO:0003676	nucleic acid binding
0.37	GO:0046872	metal ion binding
0.36	GO:0016874	ligase activity
0.36	GO:0001085	RNA polymerase II transcription factor binding
0.36	GO:0008195	phosphatidate phosphatase activity
0.36	GO:0003682	chromatin binding

0.40	GO:0005634	nucleus
0.36	GO:0031515	tRNA (m1A) methyltransferase complex
0.35	GO:0005667	transcription factor complex
0.35	GO:0070013	intracellular organelle lumen
0.35	GO:0033202	DNA helicase complex
0.35	GO:0044446	intracellular organelle part
0.34	GO:0020011	apicoplast
0.34	GO:0005783	endoplasmic reticulum
0.34	GO:0005829	cytosol
0.34	GO:0005694	chromosome

0.37	EC:2.1.1	GO:0004809
0.43	KEGG:R03876	GO:0004842

tr|T1FSV8|T1FSV8_HELRO
Uncharacterized protein
Search

0.60	GO:0002574	thrombocyte differentiation
0.57	GO:0006413	translational initiation
0.55	GO:0001207	histone displacement
0.55	GO:0051039	positive regulation of transcription involved in meiotic cell cycle
0.54	GO:0007141	male meiosis I
0.51	GO:0043484	regulation of RNA splicing
0.50	GO:0007283	spermatogenesis
0.49	GO:0006338	chromatin remodeling
0.45	GO:1901407	regulation of phosphorylation of RNA polymerase II C-terminal domain
0.45	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle

0.64	GO:0042393	histone binding
0.57	GO:0003743	translation initiation factor activity
0.57	GO:0140033	acetylation-dependent protein binding
0.55	GO:0003682	chromatin binding
0.44	GO:0000993	RNA polymerase II core binding
0.44	GO:0002039	p53 binding
0.43	GO:0008168	methyltransferase activity

0.55	GO:0000793	condensed chromosome
0.51	GO:0005634	nucleus
0.40	GO:0005829	cytosol
0.40	GO:0031974	membrane-enclosed lumen
0.37	GO:0044446	intracellular organelle part

0.43

GO:0008168

tr|T1FSV9|T1FSV9_HELRO
Uncharacterized protein
Search

tr|T1FSW0|T1FSW0_HELRO
Uncharacterized protein
Search

tr|T1FSW1|T1FSW1_HELRO
Uncharacterized protein
Search

0.49	GO:1903506	regulation of nucleic acid-templated transcription
0.45	GO:0048734	proboscis morphogenesis
0.45	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.45	GO:0010468	regulation of gene expression
0.45	GO:0048802	notum morphogenesis
0.44	GO:0007527	adult somatic muscle development
0.44	GO:0051568	histone H3-K4 methylation
0.43	GO:0045214	sarcomere organization
0.42	GO:0000209	protein polyubiquitination
0.41	GO:0036065	fucosylation

0.51	GO:0140110	transcription regulator activity
0.48	GO:0043565	sequence-specific DNA binding
0.44	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.42	GO:0008107	galactoside 2-alpha-L-fucosyltransferase activity
0.40	GO:0004842	ubiquitin-protein transferase activity
0.38	GO:0046872	metal ion binding
0.37	GO:0003723	RNA binding
0.36	GO:0030554	adenyl nucleotide binding
0.36	GO:0032555	purine ribonucleotide binding
0.36	GO:0008144	drug binding

0.52	GO:0005634	nucleus
0.42	GO:0030015	CCR4-NOT core complex
0.42	GO:0034708	methyltransferase complex
0.40	GO:0031974	membrane-enclosed lumen
0.37	GO:0044446	intracellular organelle part
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.42	EC:2.4.1.69	GO:0008107
0.40	KEGG:R03876	GO:0004842

tr|T1FSW2|T1FSW2_HELRO
Uncharacterized protein
Search

0.46	GO:0032012	regulation of ARF protein signal transduction
0.45	GO:0006397	mRNA processing
0.43	GO:0036211	protein modification process
0.42	GO:0060255	regulation of macromolecule metabolic process
0.42	GO:0006352	DNA-templated transcription, initiation
0.42	GO:0031326	regulation of cellular biosynthetic process
0.42	GO:0051171	regulation of nitrogen compound metabolic process
0.42	GO:0080090	regulation of primary metabolic process
0.42	GO:0065009	regulation of molecular function
0.41	GO:0044267	cellular protein metabolic process

0.46	GO:0005086	ARF guanyl-nucleotide exchange factor activity
0.43	GO:0140110	transcription regulator activity
0.42	GO:0003676	nucleic acid binding
0.42	GO:0004672	protein kinase activity
0.40	GO:0030554	adenyl nucleotide binding
0.40	GO:0003777	microtubule motor activity
0.40	GO:0008017	microtubule binding
0.40	GO:0097367	carbohydrate derivative binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0008144	drug binding

0.46	GO:0005634	nucleus
0.40	GO:0044446	intracellular organelle part
0.38	GO:0070013	intracellular organelle lumen
0.38	GO:0032991	macromolecular complex
0.37	GO:0044444	cytoplasmic part
0.37	GO:0031252	cell leading edge
0.36	GO:0012505	endomembrane system
0.36	GO:0012506	vesicle membrane
0.36	GO:0043232	intracellular non-membrane-bounded organelle
0.36	GO:0097708	intracellular vesicle

0.38

EC:2.4.1

GO:0004576

tr|T1FSW3|T1FSW3_HELRO
Uncharacterized protein
Search

tr|T1FSW4|T1FSW4_HELRO
Uncharacterized protein
Search

tr|T1FSW5|T1FSW5_HELRO
Uncharacterized protein
Search

tr|T1FSW6|T1FSW6_HELRO
Uncharacterized protein
Search

tr|T1FSW7|T1FSW7_HELRO
Uncharacterized protein
Search

tr|T1FSW8|T1FSW8_HELRO
Uncharacterized protein
Search

0.52	GO:0007165	signal transduction
0.42	GO:0030182	neuron differentiation
0.42	GO:0120036	plasma membrane bounded cell projection organization
0.42	GO:0048588	developmental cell growth
0.41	GO:0060560	developmental growth involved in morphogenesis
0.41	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.41	GO:0000904	cell morphogenesis involved in differentiation
0.39	GO:0048800	antennal morphogenesis
0.39	GO:0035017	cuticle pattern formation
0.39	GO:0008407	chaeta morphogenesis

0.47	GO:0032550	purine ribonucleoside binding
0.46	GO:0019001	guanyl nucleotide binding
0.42	GO:0032555	purine ribonucleotide binding
0.42	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0004012	phospholipid-translocating ATPase activity
0.38	GO:0005199	structural constituent of cell wall
0.38	GO:0016849	phosphorus-oxygen lyase activity
0.36	GO:0000287	magnesium ion binding
0.36	GO:0051536	iron-sulfur cluster binding
0.35	GO:0003676	nucleic acid binding

0.41	GO:0031252	cell leading edge
0.40	GO:0016604	nuclear body
0.39	GO:0031941	filamentous actin
0.38	GO:0005829	cytosol
0.36	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.39

EC:3.6.3.1

GO:0004012

tr|T1FSW9|T1FSW9_HELRO
Uncharacterized protein
Search

tr|T1FSX0|T1FSX0_HELRO
Uncharacterized protein
Search

tr|T1FSX1|T1FSX1_HELRO
Uncharacterized protein
Search

tr|T1FSX2|T1FSX2_HELRO
Uncharacterized protein
Search

0.56	GO:0016567	protein ubiquitination
0.35	GO:0055114	oxidation-reduction process

0.56	GO:0004842	ubiquitin-protein transferase activity
0.56	GO:0031625	ubiquitin protein ligase binding
0.54	GO:0061659	ubiquitin-like protein ligase activity
0.47	GO:0016874	ligase activity
0.43	GO:0030554	adenyl nucleotide binding
0.43	GO:0043168	anion binding
0.42	GO:0097367	carbohydrate derivative binding
0.42	GO:0008144	drug binding
0.41	GO:0003676	nucleic acid binding
0.37	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors

0.42	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

0.47	EC:6	GO:0016874
0.56	KEGG:R03876	GO:0004842

tr|T1FSX3|T1FSX3_HELRO
Uncharacterized protein
Search

0.44

GO:0030246

carbohydrate binding

0.30

GO:0044425

membrane part

tr|T1FSX4|T1FSX4_HELRO
Uncharacterized protein
Search

tr|T1FSX5|T1FSX5_HELRO
Uncharacterized protein
Search

NONO

0.84	Non-POU domain containing, octamer-binding

0.51	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
0.47	GO:0042752	regulation of circadian rhythm
0.47	GO:0002218	activation of innate immune response
0.44	GO:0000398	mRNA splicing, via spliceosome
0.44	GO:0045892	negative regulation of transcription, DNA-templated
0.39	GO:0007623	circadian rhythm
0.37	GO:0045087	innate immune response
0.36	GO:0071599	otic vesicle development
0.36	GO:0061053	somite development
0.35	GO:0006310	DNA recombination

0.59	GO:0003723	RNA binding
0.48	GO:0000976	transcription regulatory region sequence-specific DNA binding
0.48	GO:0035326	enhancer binding
0.47	GO:0001047	core promoter binding
0.45	GO:0001012	RNA polymerase II regulatory region DNA binding
0.45	GO:0003682	chromatin binding
0.45	GO:0042802	identical protein binding
0.33	GO:0003735	structural constituent of ribosome
0.32	GO:0004386	helicase activity
0.32	GO:0051539	4 iron, 4 sulfur cluster binding

0.50	GO:0042382	paraspeckles
0.48	GO:0016363	nuclear matrix
0.45	GO:0090575	RNA polymerase II transcription factor complex
0.37	GO:0016607	nuclear speck
0.36	GO:0005730	nucleolus
0.32	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

tr|T1FSX6|T1FSX6_HELRO
Uncharacterized protein
Search

tr|T1FSX7|T1FSX7_HELRO
Uncharacterized protein
Search

tr|T1FSX8|T1FSX8_HELRO
Uncharacterized protein
Search

tr|T1FSX9|T1FSX9_HELRO
Uncharacterized protein
Search

0.40	Transcription elongation factor spt6

0.75	GO:0032784	regulation of DNA-templated transcription, elongation
0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.60	GO:0061086	negative regulation of histone H3-K27 methylation
0.58	GO:0006414	translational elongation
0.55	GO:0006351	transcription, DNA-templated
0.54	GO:0010793	regulation of mRNA export from nucleus
0.53	GO:0045191	regulation of isotype switching
0.52	GO:0051147	regulation of muscle cell differentiation
0.51	GO:0050684	regulation of mRNA processing
0.50	GO:0045893	positive regulation of transcription, DNA-templated

0.85	GO:0000991	transcription factor activity, core RNA polymerase II binding
0.59	GO:0003746	translation elongation factor activity
0.55	GO:0003677	DNA binding
0.53	GO:0042393	histone binding
0.46	GO:0031491	nucleosome binding
0.40	GO:0003700	DNA binding transcription factor activity
0.32	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.32	GO:0051536	iron-sulfur cluster binding
0.31	GO:0009055	electron transfer activity

0.59	GO:0005634	nucleus
0.48	GO:0035327	transcriptionally active chromatin
0.42	GO:0070013	intracellular organelle lumen
0.40	GO:0043234	protein complex
0.37	GO:0005703	polytene chromosome puff
0.37	GO:0005705	polytene chromosome interband
0.36	GO:0000178	exosome (RNase complex)
0.30	GO:0016020	membrane

0.32

EC:1.6.5.3

GO:0008137

tr|T1FSY0|T1FSY0_HELRO
Uncharacterized protein
Search

tr|T1FSY1|T1FSY1_HELRO
Uncharacterized protein
Search

tr|T1FSY2|T1FSY2_HELRO
RuvB-like helicase
Search

RUVBL1

0.64	RuvB-like helicase

0.70	GO:0032392	DNA geometric change
0.63	GO:0006281	DNA repair
0.60	GO:0016569	covalent chromatin modification
0.59	GO:0006310	DNA recombination
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:1904874	positive regulation of telomerase RNA localization to Cajal body
0.54	GO:1903146	regulation of autophagy of mitochondrion

0.81	GO:0043141	ATP-dependent 5'-3' DNA helicase activity
0.55	GO:0001094	TFIID-class transcription factor binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0051117	ATPase binding
0.52	GO:0045296	cadherin binding
0.34	GO:0043140	ATP-dependent 3'-5' DNA helicase activity

0.83	GO:0097255	R2TP complex
0.80	GO:0035267	NuA4 histone acetyltransferase complex
0.80	GO:0031011	Ino80 complex
0.56	GO:0000812	Swr1 complex
0.52	GO:0071339	MLL1 complex
0.46	GO:0005829	cytosol
0.43	GO:0030529	intracellular ribonucleoprotein complex
0.36	GO:0016363	nuclear matrix
0.36	GO:0070062	extracellular exosome
0.34	GO:0005815	microtubule organizing center

0.81

EC:3.6.1

GO:0043141

tr|T1FSY3|T1FSY3_HELRO
Uncharacterized protein
Search

0.41	GO:0010951	negative regulation of endopeptidase activity
0.40	GO:1903354	regulation of distal tip cell migration
0.40	GO:0035262	gonad morphogenesis
0.39	GO:0006898	receptor-mediated endocytosis
0.39	GO:0007155	cell adhesion
0.38	GO:0009792	embryo development ending in birth or egg hatching
0.36	GO:0008104	protein localization
0.35	GO:0016043	cellular component organization
0.35	GO:0006508	proteolysis

0.64	GO:0005201	extracellular matrix structural constituent
0.41	GO:0004867	serine-type endopeptidase inhibitor activity
0.41	GO:0005044	scavenger receptor activity
0.38	GO:0008201	heparin binding
0.37	GO:0042302	structural constituent of cuticle
0.36	GO:0004222	metalloendopeptidase activity
0.36	GO:0005509	calcium ion binding

0.75	GO:0005581	collagen trimer
0.65	GO:0044420	extracellular matrix component
0.61	GO:0005578	proteinaceous extracellular matrix
0.39	GO:0099081	supramolecular polymer
0.30	GO:0016020	membrane

0.36

GO:0004222

tr|T1FSY4|T1FSY4_HELRO
Uncharacterized protein
Search

0.67	GO:0007010	cytoskeleton organization
0.43	GO:0072499	photoreceptor cell axon guidance
0.36	GO:0010591	regulation of lamellipodium assembly
0.36	GO:0051489	regulation of filopodium assembly

0.69	GO:0003779	actin binding
0.53	GO:0046872	metal ion binding
0.35	GO:0032403	protein complex binding

0.37	GO:0005654	nucleoplasm
0.36	GO:0009925	basal plasma membrane
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1FSY5|T1FSY5_HELRO
Uncharacterized protein
Search

0.61	COUP transcription factor

0.76	GO:0043401	steroid hormone mediated signaling pathway
0.74	GO:0030522	intracellular receptor signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.40	GO:0001935	endothelial cell proliferation
0.40	GO:0001944	vasculature development
0.37	GO:0021796	cerebral cortex regionalization
0.36	GO:0010977	negative regulation of neuron projection development

0.77	GO:0003707	steroid hormone receptor activity
0.77	GO:0004879	nuclear receptor activity
0.62	GO:0043565	sequence-specific DNA binding
0.60	GO:0008270	zinc ion binding
0.36	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.35	GO:0001012	RNA polymerase II regulatory region DNA binding
0.35	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|T1FSY6|T1FSY6_HELRO
Uncharacterized protein
Search

0.79	GO:0007229	integrin-mediated signaling pathway
0.72	GO:0007155	cell adhesion
0.43	GO:2000721	positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation
0.42	GO:1903846	positive regulation of cellular response to transforming growth factor beta stimulus
0.42	GO:0048745	smooth muscle tissue development
0.41	GO:0048333	mesodermal cell differentiation
0.41	GO:0001656	metanephros development
0.41	GO:0042472	inner ear morphogenesis
0.41	GO:0007613	memory
0.41	GO:0090100	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway

0.33

GO:0046872

metal ion binding

0.81	GO:0008305	integrin complex
0.40	GO:0045177	apical part of cell
0.39	GO:0009986	cell surface
0.38	GO:0005783	endoplasmic reticulum

tr|T1FSY7|T1FSY7_HELRO
Uncharacterized protein
Search

tr|T1FSY8|T1FSY8_HELRO
Uncharacterized protein
Search

0.71	Plasma membrane calcium-transporting ATPase 3

0.75	GO:0070588	calcium ion transmembrane transport
0.67	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.44	GO:1990034	calcium ion export across plasma membrane
0.43	GO:0006874	cellular calcium ion homeostasis
0.37	GO:0071386	cellular response to corticosterone stimulus
0.36	GO:0071305	cellular response to vitamin D
0.36	GO:0003407	neural retina development
0.35	GO:0008016	regulation of heart contraction
0.35	GO:0009628	response to abiotic stimulus
0.35	GO:0007568	aging

0.78	GO:0005388	calcium-transporting ATPase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0030165	PDZ domain binding
0.37	GO:0005516	calmodulin binding
0.35	GO:0036487	nitric-oxide synthase inhibitor activity
0.35	GO:0030346	protein phosphatase 2B binding
0.35	GO:0050998	nitric-oxide synthase binding

0.37	GO:0005634	nucleus
0.37	GO:0005887	integral component of plasma membrane
0.36	GO:0032591	dendritic spine membrane
0.36	GO:0032809	neuronal cell body membrane
0.35	GO:0016323	basolateral plasma membrane
0.35	GO:0016324	apical plasma membrane
0.35	GO:0070062	extracellular exosome
0.35	GO:0098857	membrane microdomain
0.35	GO:0009898	cytoplasmic side of plasma membrane
0.34	GO:0030315	T-tubule

0.78

EC:3.6.3.8

GO:0005388

tr|T1FSY9|T1FSY9_HELRO
Uncharacterized protein
Search

tr|T1FSZ0|T1FSZ0_HELRO
Uncharacterized protein
Search

TMEM115

0.44	Testicular tissue protein Li 201

0.81	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.49	GO:0006486	protein glycosylation
0.34	GO:0001302	replicative cell aging
0.34	GO:0008285	negative regulation of cell proliferation
0.34	GO:0006888	ER to Golgi vesicle-mediated transport
0.33	GO:0015031	protein transport

0.49	GO:0042802	identical protein binding
0.33	GO:0004386	helicase activity

0.52	GO:0017119	Golgi transport complex
0.52	GO:0032580	Golgi cisterna membrane
0.43	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

tr|T1FSZ1|T1FSZ1_HELRO
Uncharacterized protein
Search

tr|T1FSZ2|T1FSZ2_HELRO
Uncharacterized protein
Search

0.39	GO:0016573	histone acetylation
0.38	GO:0060255	regulation of macromolecule metabolic process
0.38	GO:0080090	regulation of primary metabolic process
0.38	GO:0031323	regulation of cellular metabolic process
0.38	GO:0051171	regulation of nitrogen compound metabolic process
0.38	GO:0009889	regulation of biosynthetic process
0.37	GO:0007165	signal transduction
0.36	GO:0071773	cellular response to BMP stimulus
0.36	GO:0060828	regulation of canonical Wnt signaling pathway
0.35	GO:0048513	animal organ development

0.55	GO:0005509	calcium ion binding
0.41	GO:0008270	zinc ion binding
0.40	GO:0003712	transcription cofactor activity
0.40	GO:0004402	histone acetyltransferase activity
0.37	GO:0030229	very-low-density lipoprotein particle receptor activity
0.36	GO:0004871	signal transducer activity
0.36	GO:0099600	transmembrane receptor activity
0.35	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.35	GO:0003700	DNA binding transcription factor activity
0.35	GO:0004829	threonine-tRNA ligase activity

0.41	GO:0043231	intracellular membrane-bounded organelle
0.40	GO:0012505	endomembrane system
0.38	GO:0031248	protein acetyltransferase complex
0.37	GO:0044444	cytoplasmic part
0.37	GO:0031974	membrane-enclosed lumen
0.36	GO:0031588	nucleotide-activated protein kinase complex
0.35	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

0.40

GO:0004402

tr|T1FSZ3|T1FSZ3_HELRO
Uncharacterized protein
Search

0.63	GO:0006468	protein phosphorylation
0.51	GO:0031098	stress-activated protein kinase signaling cascade
0.51	GO:1904355	positive regulation of telomere capping
0.50	GO:0051973	positive regulation of telomerase activity
0.50	GO:0032147	activation of protein kinase activity
0.50	GO:0032212	positive regulation of telomere maintenance via telomerase
0.49	GO:0034612	response to tumor necrosis factor
0.48	GO:0043406	positive regulation of MAP kinase activity
0.48	GO:0009411	response to UV
0.47	GO:0006970	response to osmotic stress

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0019901	protein kinase binding
0.42	GO:0000287	magnesium ion binding
0.42	GO:0004871	signal transducer activity
0.37	GO:0019903	protein phosphatase binding
0.34	GO:0008022	protein C-terminus binding
0.34	GO:0008009	chemokine activity

0.36	GO:0005622	intracellular
0.34	GO:0043227	membrane-bounded organelle
0.33	GO:0005576	extracellular region
0.30	GO:0016020	membrane

tr|T1FSZ4|T1FSZ4_HELRO
Uncharacterized protein
Search

0.10	Disintegrin and metalloproteinase domain-containing protein 10-like

0.84	GO:0006509	membrane protein ectodomain proteolysis
0.79	GO:0007219	Notch signaling pathway
0.66	GO:0007229	integrin-mediated signaling pathway
0.52	GO:0042117	monocyte activation
0.51	GO:0010820	positive regulation of T cell chemotaxis
0.49	GO:0007162	negative regulation of cell adhesion
0.49	GO:0034612	response to tumor necrosis factor
0.49	GO:0030307	positive regulation of cell growth
0.47	GO:0008284	positive regulation of cell proliferation
0.46	GO:0001701	in utero embryonic development

0.70	GO:0004222	metalloendopeptidase activity
0.54	GO:0046872	metal ion binding
0.48	GO:0019901	protein kinase binding
0.47	GO:0042803	protein homodimerization activity
0.38	GO:0017124	SH3 domain binding
0.34	GO:0042169	SH2 domain binding
0.34	GO:0005178	integrin binding

0.51	GO:0097197	tetraspanin-enriched microdomain
0.50	GO:0097038	perinuclear endoplasmic reticulum
0.49	GO:0014069	postsynaptic density
0.47	GO:0005798	Golgi-associated vesicle
0.47	GO:0009986	cell surface
0.46	GO:0005615	extracellular space
0.45	GO:0005794	Golgi apparatus
0.42	GO:0005634	nucleus
0.36	GO:0098588	bounding membrane of organelle
0.36	GO:0031984	organelle subcompartment

0.70

GO:0004222

tr|T1FSZ5|T1FSZ5_HELRO
Uncharacterized protein
Search

tr|T1FSZ6|T1FSZ6_HELRO
Uncharacterized protein
Search

tr|T1FSZ7|T1FSZ7_HELRO
Uncharacterized protein
Search

0.85	GO:0009301	snRNA transcription
0.54	GO:0035622	intrahepatic bile duct development
0.51	GO:0031016	pancreas development
0.49	GO:0008283	cell proliferation
0.43	GO:0006383	transcription by RNA polymerase III
0.42	GO:0006366	transcription by RNA polymerase II
0.41	GO:0030154	cell differentiation
0.40	GO:0006357	regulation of transcription by RNA polymerase II
0.40	GO:0090307	mitotic spindle assembly

0.55	GO:0003677	DNA binding
0.44	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting
0.42	GO:0001067	regulatory region nucleic acid binding
0.41	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding

0.86

GO:0019185

snRNA-activating protein complex

tr|T1FSZ8|T1FSZ8_HELRO
Uncharacterized protein
Search

tr|T1FSZ9|T1FSZ9_HELRO
Uncharacterized protein
Search

IF2B1

0.79	IGF-II mRNA-binding protein, isoform L

0.49	GO:0048680	positive regulation of axon regeneration
0.48	GO:0051124	synaptic growth at neuromuscular junction
0.48	GO:0016322	neuron remodeling
0.45	GO:0007283	spermatogenesis
0.45	GO:0042594	response to starvation
0.39	GO:0005975	carbohydrate metabolic process
0.39	GO:0000398	mRNA splicing, via spliceosome
0.33	GO:0055085	transmembrane transport

0.59

GO:0003723

RNA binding

0.46	GO:0043025	neuronal cell body
0.45	GO:0030424	axon
0.40	GO:0071011	precatalytic spliceosome
0.40	GO:0071013	catalytic step 2 spliceosome
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|T1FT00|T1FT00_HELRO
Uncharacterized protein
Search

0.60	GO:0045475	locomotor rhythm
0.36	GO:0055080	cation homeostasis
0.35	GO:0098655	cation transmembrane transport

0.36

GO:0005261

cation channel activity

0.37

GO:0034703

cation channel complex

tr|T1FT01|T1FT01_HELRO
Uncharacterized protein
Search

TAF2

0.80	Transcription initiation factor TFIID subunit 2

0.58	GO:0006413	translational initiation
0.52	GO:0006367	transcription initiation from RNA polymerase II promoter
0.51	GO:0000086	G2/M transition of mitotic cell cycle
0.50	GO:0045944	positive regulation of transcription by RNA polymerase II
0.48	GO:0006508	proteolysis
0.46	GO:0070897	DNA-templated transcriptional preinitiation complex assembly
0.36	GO:0046427	positive regulation of JAK-STAT cascade
0.36	GO:2000144	positive regulation of DNA-templated transcription, initiation
0.35	GO:0060260	regulation of transcription initiation from RNA polymerase II promoter
0.35	GO:0007219	Notch signaling pathway

0.59	GO:0003743	translation initiation factor activity
0.52	GO:0008237	metallopeptidase activity
0.50	GO:0044212	transcription regulatory region DNA binding
0.50	GO:0008270	zinc ion binding
0.49	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly
0.48	GO:0001129	RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly
0.44	GO:0003682	chromatin binding
0.41	GO:0043565	sequence-specific DNA binding
0.34	GO:0008134	transcription factor binding
0.33	GO:0004177	aminopeptidase activity

0.80	GO:0005669	transcription factor TFIID complex
0.52	GO:0033276	transcription factor TFTC complex
0.34	GO:0031390	Ctf18 RFC-like complex
0.30	GO:0016020	membrane

0.33

EC:3.4.11

GO:0004177

tr|T1FT02|T1FT02_HELRO
Uncharacterized protein
Search

tr|T1FT03|T1FT03_HELRO
Uncharacterized protein
Search

tr|T1FT04|T1FT04_HELRO
Uncharacterized protein
Search

tr|T1FT05|T1FT05_HELRO
Uncharacterized protein
Search

0.61	GO:0006508	proteolysis
0.46	GO:0051307	meiotic chromosome separation
0.37	GO:1903047	mitotic cell cycle process
0.36	GO:0000819	sister chromatid segregation
0.35	GO:0000212	meiotic spindle organization
0.35	GO:0045143	homologous chromosome segregation
0.35	GO:0009960	endosperm development
0.34	GO:0045876	positive regulation of sister chromatid cohesion
0.34	GO:0043413	macromolecule glycosylation
0.34	GO:0009101	glycoprotein biosynthetic process

0.61	GO:0008233	peptidase activity
0.35	GO:0008378	galactosyltransferase activity
0.33	GO:0005200	structural constituent of cytoskeleton

0.61	GO:0005634	nucleus
0.44	GO:0072686	mitotic spindle
0.44	GO:0005813	centrosome
0.35	GO:0005737	cytoplasm
0.35	GO:1990520	separase-securin complex
0.34	GO:0044732	mitotic spindle pole body
0.34	GO:0051233	spindle midzone
0.34	GO:0031262	Ndc80 complex
0.33	GO:0000777	condensed chromosome kinetochore
0.33	GO:0005874	microtubule

0.61

GO:0008233

tr|T1FT06|T1FT06_HELRO
Uncharacterized protein
Search

tr|T1FT07|T1FT07_HELRO
Uncharacterized protein
Search

tr|T1FT08|T1FT08_HELRO
Uncharacterized protein
Search

tr|T1FT09|T1FT09_HELRO
Uncharacterized protein
Search

0.45	GO:0036065	fucosylation
0.44	GO:0045893	positive regulation of transcription, DNA-templated
0.43	GO:0010928	regulation of auxin mediated signaling pathway
0.43	GO:2000219	positive regulation of invasive growth in response to glucose limitation
0.43	GO:0006357	regulation of transcription by RNA polymerase II
0.43	GO:0070202	regulation of establishment of protein localization to chromosome
0.42	GO:2000028	regulation of photoperiodism, flowering
0.42	GO:0055085	transmembrane transport
0.42	GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly
0.41	GO:0009734	auxin-activated signaling pathway

0.50	GO:0033830	Skp1-protein-hydroxyproline N-acetylglucosaminyltransferase activity
0.47	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting
0.47	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.46	GO:0008107	galactoside 2-alpha-L-fucosyltransferase activity
0.44	GO:0001088	transcription factor activity, TFIIE-class binding
0.44	GO:0001095	TFIIE-class transcription factor binding
0.44	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity
0.43	GO:0008193	tRNA guanylyltransferase activity
0.43	GO:0001097	TFIIH-class transcription factor binding
0.43	GO:0030554	adenyl nucleotide binding

0.45	GO:0005882	intermediate filament
0.42	GO:0070847	core mediator complex
0.40	GO:0016592	mediator complex
0.37	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.50

EC:2.4.1.229

GO:0033830

tr|T1FT10|T1FT10_HELRO
Uncharacterized protein
Search

tr|T1FT11|T1FT11_HELRO
Uncharacterized protein
Search

0.41	GO:0060255	regulation of macromolecule metabolic process
0.41	GO:0044265	cellular macromolecule catabolic process
0.40	GO:0043412	macromolecule modification
0.40	GO:0006683	galactosylceramide catabolic process
0.40	GO:0044267	cellular protein metabolic process
0.39	GO:0080090	regulation of primary metabolic process
0.39	GO:0051171	regulation of nitrogen compound metabolic process
0.39	GO:0031323	regulation of cellular metabolic process
0.39	GO:0009889	regulation of biosynthetic process
0.39	GO:0034655	nucleobase-containing compound catabolic process

0.40	GO:0004336	galactosylceramidase activity
0.40	GO:0140110	transcription regulator activity
0.39	GO:0004672	protein kinase activity
0.39	GO:0031625	ubiquitin protein ligase binding
0.39	GO:0003676	nucleic acid binding
0.38	GO:0005518	collagen binding
0.37	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0004402	histone acetyltransferase activity
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding

0.42	GO:0030014	CCR4-NOT complex
0.39	GO:1990234	transferase complex
0.38	GO:0005634	nucleus
0.37	GO:0044175	host cell endosome membrane
0.37	GO:0020011	apicoplast
0.36	GO:0005618	cell wall
0.36	GO:0020002	host cell plasma membrane
0.36	GO:0036338	viral membrane
0.36	GO:0055036	virion membrane
0.36	GO:0005576	extracellular region

0.40

EC:3.2.1.46

GO:0004336

tr|T1FT12|T1FT12_HELRO
Uncharacterized protein
Search

tr|T1FT13|T1FT13_HELRO
Uncharacterized protein
Search

tr|T1FT14|T1FT14_HELRO
Uncharacterized protein
Search

0.45	GO:0036211	protein modification process
0.43	GO:0044267	cellular protein metabolic process
0.42	GO:0016310	phosphorylation
0.39	GO:0007018	microtubule-based movement
0.38	GO:2001141	regulation of RNA biosynthetic process
0.38	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.38	GO:0090304	nucleic acid metabolic process
0.38	GO:0010468	regulation of gene expression
0.37	GO:0006974	cellular response to DNA damage stimulus
0.37	GO:0000086	G2/M transition of mitotic cell cycle

0.44	GO:0140096	catalytic activity, acting on a protein
0.43	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.43	GO:0016301	kinase activity
0.43	GO:0097367	carbohydrate derivative binding
0.42	GO:0017076	purine nucleotide binding
0.42	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0046872	metal ion binding
0.41	GO:0008144	drug binding
0.40	GO:0017111	nucleoside-triphosphatase activity
0.40	GO:0140110	transcription regulator activity

0.40	GO:0030286	dynein complex
0.37	GO:0032221	Rpd3S complex
0.37	GO:0033698	Rpd3L complex
0.37	GO:0020011	apicoplast
0.36	GO:0032865	ERMES complex
0.36	GO:0031307	integral component of mitochondrial outer membrane
0.35	GO:0016459	myosin complex

0.43

GO:0016773

tr|T1FT15|T1FT15_HELRO
Uncharacterized protein
Search

0.71	GO:0006470	protein dephosphorylation
0.50	GO:0000188	inactivation of MAPK activity
0.42	GO:0043508	negative regulation of JUN kinase activity
0.38	GO:0007400	neuroblast fate determination
0.37	GO:0007474	imaginal disc-derived wing vein specification
0.37	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA
0.37	GO:0050832	defense response to fungus
0.35	GO:0043085	positive regulation of catalytic activity

0.78	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.66	GO:0004725	protein tyrosine phosphatase activity
0.50	GO:0033549	MAP kinase phosphatase activity
0.36	GO:0008047	enzyme activator activity

0.30

GO:0016020

membrane

0.78

EC:3.1.3

GO:0008138

tr|T1FT16|T1FT16_HELRO
Uncharacterized protein
Search

tr|T1FT17|T1FT17_HELRO
Uncharacterized protein
Search

0.60	GO:0035556	intracellular signal transduction
0.37	GO:0007062	sister chromatid cohesion
0.36	GO:0006913	nucleocytoplasmic transport
0.36	GO:0006260	DNA replication
0.36	GO:0000070	mitotic sister chromatid segregation
0.35	GO:1903778	protein localization to vacuolar membrane
0.35	GO:0010513	positive regulation of phosphatidylinositol biosynthetic process
0.35	GO:0051568	histone H3-K4 methylation
0.34	GO:0030261	chromosome condensation
0.34	GO:0033674	positive regulation of kinase activity

0.42	GO:0045735	nutrient reservoir activity
0.38	GO:0017056	structural constituent of nuclear pore
0.35	GO:0045322	unmethylated CpG binding
0.34	GO:0003700	DNA binding transcription factor activity
0.34	GO:0015035	protein disulfide oxidoreductase activity
0.33	GO:0009055	electron transfer activity
0.33	GO:0046872	metal ion binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.44	GO:0005622	intracellular
0.36	GO:0043226	organelle
0.36	GO:0043234	protein complex
0.36	GO:0012505	endomembrane system
0.35	GO:1990234	transferase complex
0.35	GO:0031975	envelope
0.34	GO:0019898	extrinsic component of membrane
0.34	GO:0098805	whole membrane
0.33	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

tr|T1FT18|T1FT18_HELRO
Uncharacterized protein
Search

0.49	GO:0072577	endothelial cell apoptotic process
0.49	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.48	GO:0032836	glomerular basement membrane development
0.47	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.46	GO:0016525	negative regulation of angiogenesis
0.45	GO:0008283	cell proliferation
0.42	GO:0007155	cell adhesion
0.39	GO:0009887	animal organ morphogenesis
0.39	GO:0010466	negative regulation of peptidase activity
0.39	GO:0001501	skeletal system development

0.66	GO:0005201	extracellular matrix structural constituent
0.46	GO:0005178	integrin binding
0.39	GO:0030414	peptidase inhibitor activity
0.39	GO:0061135	endopeptidase regulator activity
0.38	GO:0005044	scavenger receptor activity
0.37	GO:0042302	structural constituent of cuticle
0.36	GO:0008201	heparin binding
0.33	GO:0042802	identical protein binding
0.33	GO:0030246	carbohydrate binding
0.33	GO:0005509	calcium ion binding

0.68	GO:0005581	collagen trimer
0.59	GO:0005604	basement membrane
0.50	GO:0098645	collagen network
0.42	GO:0005783	endoplasmic reticulum
0.37	GO:0031594	neuromuscular junction
0.35	GO:0005911	cell-cell junction
0.33	GO:0019867	outer membrane
0.33	GO:0070013	intracellular organelle lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

0.33

GO:0004553

tr|T1FT19|T1FT19_HELRO
Uncharacterized protein
Search

0.55	Transmembrane protein 9

0.36

GO:0071586

CAAX-box protein processing

0.35

GO:0004222

metalloendopeptidase activity

0.30

GO:0031224

intrinsic component of membrane

0.35

GO:0004222

tr|T1FT20|T1FT20_HELRO
Uncharacterized protein
Search

tr|T1FT21|T1FT21_HELRO
Uncharacterized protein
Search

tr|T1FT22|T1FT22_HELRO
Uncharacterized protein
Search

0.72	GO:0043547	positive regulation of GTPase activity
0.42	GO:0000902	cell morphogenesis
0.35	GO:0051013	microtubule severing
0.35	GO:0034968	histone lysine methylation
0.35	GO:0007165	signal transduction
0.35	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA
0.34	GO:1904059	regulation of locomotor rhythm
0.34	GO:0045314	regulation of compound eye photoreceptor development
0.34	GO:0030725	germline ring canal formation
0.34	GO:0035317	imaginal disc-derived wing hair organization

0.73	GO:0005096	GTPase activator activity
0.50	GO:0046872	metal ion binding
0.40	GO:0019901	protein kinase binding
0.36	GO:0003924	GTPase activity
0.35	GO:0032550	purine ribonucleoside binding
0.35	GO:0032561	guanyl ribonucleotide binding
0.35	GO:0018024	histone-lysine N-methyltransferase activity
0.35	GO:0005543	phospholipid binding
0.34	GO:0008017	microtubule binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.36	GO:0008352	katanin complex
0.34	GO:0005874	microtubule
0.34	GO:0045179	apical cortex
0.34	GO:0030686	90S preribosome
0.34	GO:0043296	apical junction complex
0.33	GO:0005634	nucleus
0.33	GO:0043233	organelle lumen
0.33	GO:0005694	chromosome
0.30	GO:0031224	intrinsic component of membrane

0.35

GO:0018024

tr|T1FT23|T1FT23_HELRO
Uncharacterized protein
Search

0.61	GO:0070588	calcium ion transmembrane transport
0.53	GO:0050976	detection of mechanical stimulus involved in sensory perception of touch
0.52	GO:0010996	response to auditory stimulus
0.52	GO:0007638	mechanosensory behavior
0.52	GO:0001964	startle response
0.51	GO:0071260	cellular response to mechanical stimulus
0.50	GO:0007605	sensory perception of sound
0.44	GO:0040011	locomotion
0.40	GO:0043666	regulation of phosphoprotein phosphatase activity
0.36	GO:0016567	protein ubiquitination

0.62	GO:0005262	calcium channel activity
0.45	GO:0003723	RNA binding
0.44	GO:0030506	ankyrin binding
0.40	GO:0019888	protein phosphatase regulator activity
0.40	GO:0022836	gated channel activity
0.36	GO:0004842	ubiquitin-protein transferase activity
0.36	GO:0004672	protein kinase activity
0.35	GO:0031625	ubiquitin protein ligase binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding

0.53	GO:0044214	spanning component of plasma membrane
0.49	GO:0043025	neuronal cell body
0.49	GO:0030425	dendrite
0.48	GO:0005929	cilium
0.41	GO:0034703	cation channel complex
0.36	GO:0030907	MBF transcription complex
0.35	GO:0000151	ubiquitin ligase complex
0.32	GO:0005737	cytoplasm

0.34	EC:2.3.1	GO:0016747
0.36	KEGG:R03876	GO:0004842

tr|T1FT24|T1FT24_HELRO
Glutamine-dependent NAD(+) synthetase
Search

NADSYN1

0.56	Glutamine-dependent NAD(+) synthetase

0.73	GO:0009435	NAD biosynthetic process
0.36	GO:0051209	release of sequestered calcium ion into cytosol
0.33	GO:0007165	signal transduction

0.79	GO:0003952	NAD+ synthase (glutamine-hydrolyzing) activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0004359	glutaminase activity
0.36	GO:0072345	NAADP-sensitive calcium-release channel activity
0.35	GO:0005245	voltage-gated calcium channel activity
0.35	GO:0008795	NAD+ synthase activity
0.33	GO:0005515	protein binding

0.45	GO:0005829	cytosol
0.39	GO:0005634	nucleus
0.35	GO:0005765	lysosomal membrane
0.30	GO:0016021	integral component of membrane

0.79

EC:6.3.5.1

GO:0003952

tr|T1FT25|T1FT25_HELRO
Uncharacterized protein
Search

0.70	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.43	GO:0001558	regulation of cell growth
0.42	GO:1990126	retrograde transport, endosome to plasma membrane
0.42	GO:0051960	regulation of nervous system development
0.41	GO:0008361	regulation of cell size
0.41	GO:0010769	regulation of cell morphogenesis involved in differentiation
0.40	GO:0048638	regulation of developmental growth
0.40	GO:0120035	regulation of plasma membrane bounded cell projection organization
0.40	GO:0048699	generation of neurons
0.38	GO:0050806	positive regulation of synaptic transmission

0.65	GO:0005509	calcium ion binding
0.40	GO:0042988	X11-like protein binding
0.39	GO:0001540	amyloid-beta binding
0.38	GO:0019894	kinesin binding
0.37	GO:0140110	transcription regulator activity
0.36	GO:0001187	RNA polymerase I CORE element sequence-specific DNA binding
0.36	GO:0004842	ubiquitin-protein transferase activity
0.36	GO:0048257	3'-flap endonuclease activity
0.36	GO:0008270	zinc ion binding
0.36	GO:0005085	guanyl-nucleotide exchange factor activity

0.38	GO:0014069	postsynaptic density
0.37	GO:0045211	postsynaptic membrane
0.37	GO:0044798	nuclear transcription factor complex
0.37	GO:0009986	cell surface
0.37	GO:0005615	extracellular space
0.36	GO:0005730	nucleolus
0.35	GO:0030126	COPI vesicle coat
0.35	GO:0048476	Holliday junction resolvase complex
0.30	GO:0016021	integral component of membrane

0.35	EC:3.1.3.33	GO:0004651
0.36	KEGG:R03876	GO:0004842

tr|T1FT26|T1FT26_HELRO
Uncharacterized protein
Search

tr|T1FT27|T1FT27_HELRO
Uncharacterized protein
Search

0.71	GO:0030036	actin cytoskeleton organization
0.69	GO:0016477	cell migration
0.63	GO:0006468	protein phosphorylation
0.60	GO:0035556	intracellular signal transduction
0.32	GO:0007163	establishment or maintenance of cell polarity
0.31	GO:0055114	oxidation-reduction process

0.70	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0046872	metal ion binding
0.41	GO:0032403	protein complex binding
0.34	GO:0017048	Rho GTPase binding
0.32	GO:0032440	2-alkenal reductase [NAD(P)] activity

0.44	GO:0042641	actomyosin
0.34	GO:0030027	lamellipodium
0.33	GO:0005911	cell-cell junction
0.33	GO:0070062	extracellular exosome
0.32	GO:0005886	plasma membrane
0.32	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.70

GO:0004674

tr|T1FT28|T1FT28_HELRO
Protein Wnt
Search

tr|T1FT29|T1FT29_HELRO
Uncharacterized protein
Search

0.74	GO:0043547	positive regulation of GTPase activity
0.60	GO:0007165	signal transduction
0.57	GO:0021816	extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration
0.55	GO:0046847	filopodium assembly
0.54	GO:0060996	dendritic spine development
0.51	GO:0048812	neuron projection morphogenesis
0.46	GO:0030336	negative regulation of cell migration
0.39	GO:2001222	regulation of neuron migration
0.39	GO:0003363	lamellipodium assembly involved in ameboidal cell migration
0.38	GO:0051014	actin filament severing

0.75	GO:0005096	GTPase activator activity
0.56	GO:0048365	Rac GTPase binding
0.49	GO:0042803	protein homodimerization activity
0.33	GO:0046982	protein heterodimerization activity
0.33	GO:0035091	phosphatidylinositol binding

0.52	GO:0045335	phagocytic vesicle
0.52	GO:0014069	postsynaptic density
0.51	GO:0045211	postsynaptic membrane
0.46	GO:0005829	cytosol
0.43	GO:0031966	mitochondrial membrane
0.43	GO:0019866	organelle inner membrane
0.39	GO:0044327	dendritic spine head
0.38	GO:0030027	lamellipodium
0.37	GO:0030054	cell junction
0.35	GO:0005634	nucleus

tr|T1FT30|T1FT30_HELRO
Uncharacterized protein
Search

0.37	GO:0007304	chorion-containing eggshell formation
0.37	GO:0006904	vesicle docking involved in exocytosis
0.37	GO:0034968	histone lysine methylation
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:0010468	regulation of gene expression
0.35	GO:0016311	dephosphorylation
0.35	GO:0016310	phosphorylation
0.34	GO:0035556	intracellular signal transduction
0.34	GO:0005975	carbohydrate metabolic process

0.49	GO:0003676	nucleic acid binding
0.37	GO:0000829	inositol heptakisphosphate kinase activity
0.37	GO:0018024	histone-lysine N-methyltransferase activity
0.37	GO:0003700	DNA binding transcription factor activity
0.37	GO:0030248	cellulose binding
0.37	GO:0003993	acid phosphatase activity
0.35	GO:0004674	protein serine/threonine kinase activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.38	GO:0005634	nucleus
0.35	GO:0019866	organelle inner membrane
0.35	GO:0031966	mitochondrial membrane
0.35	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.37

GO:0018024

tr|T1FT31|T1FT31_HELRO
Uncharacterized protein
Search

0.53	GO:0006508	proteolysis
0.36	GO:0006260	DNA replication
0.35	GO:1903506	regulation of nucleic acid-templated transcription
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression

0.69	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.63	GO:0005509	calcium ion binding
0.45	GO:0003723	RNA binding
0.37	GO:0003697	single-stranded DNA binding

0.42	GO:0005622	intracellular
0.41	GO:0019013	viral nucleocapsid
0.38	GO:1990904	ribonucleoprotein complex
0.30	GO:0044425	membrane part

tr|T1FT32|T1FT32_HELRO
Uncharacterized protein
Search

tr|T1FT33|T1FT33_HELRO
Uncharacterized protein
Search

0.61	Cys-loop ligand-gated ion channel

0.61	GO:0007165	signal transduction
0.60	GO:0034220	ion transmembrane transport

0.76	GO:0005230	extracellular ligand-gated ion channel activity
0.70	GO:0099600	transmembrane receptor activity
0.65	GO:0038023	signaling receptor activity

0.30

GO:0031224

intrinsic component of membrane

tr|T1FT34|T1FT34_HELRO
Uncharacterized protein
Search

0.41	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.41	GO:0008380	RNA splicing
0.39	GO:0042981	regulation of apoptotic process
0.36	GO:0006397	mRNA processing
0.35	GO:0070935	3'-UTR-mediated mRNA stabilization
0.35	GO:0048025	negative regulation of mRNA splicing, via spliceosome
0.35	GO:0006359	regulation of transcription by RNA polymerase III
0.35	GO:0008285	negative regulation of cell proliferation
0.35	GO:0043068	positive regulation of programmed cell death
0.34	GO:0006383	transcription by RNA polymerase III

0.55	GO:0003723	RNA binding
0.50	GO:0046872	metal ion binding
0.35	GO:0001026	TFIIIB-type transcription factor activity
0.32	GO:0003677	DNA binding

0.40	GO:0005681	spliceosomal complex
0.35	GO:0000126	transcription factor TFIIIB complex
0.35	GO:0016607	nuclear speck

tr|T1FT35|T1FT35_HELRO
Uncharacterized protein
Search

0.44	GO:0070868	heterochromatin organization involved in chromatin silencing
0.43	GO:0031935	regulation of chromatin silencing
0.43	GO:0007476	imaginal disc-derived wing morphogenesis
0.42	GO:0030178	negative regulation of Wnt signaling pathway
0.42	GO:0045931	positive regulation of mitotic cell cycle
0.40	GO:0007155	cell adhesion
0.40	GO:0006357	regulation of transcription by RNA polymerase II
0.35	GO:0045138	nematode male tail tip morphogenesis
0.35	GO:0002164	larval development
0.35	GO:0051402	neuron apoptotic process

0.51	GO:0003676	nucleic acid binding
0.37	GO:0046872	metal ion binding
0.36	GO:0003700	DNA binding transcription factor activity
0.33	GO:0008324	cation transmembrane transporter activity
0.32	GO:0008168	methyltransferase activity
0.32	GO:0046982	protein heterodimerization activity

0.42	GO:0000792	heterochromatin
0.39	GO:0005634	nucleus
0.32	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

0.32

GO:0008168

tr|T1FT36|T1FT36_HELRO
Uncharacterized protein
Search

tr|T1FT37|T1FT37_HELRO
Uncharacterized protein
Search

0.44	Putative conserved plasma membrane protein (Fragment)

0.30

GO:0044425

membrane part

tr|T1FT38|T1FT38_HELRO
Uncharacterized protein
Search

0.60	Cys-loop ligand-gated ion channel

0.61	GO:0007165	signal transduction
0.60	GO:0034220	ion transmembrane transport

0.76	GO:0005230	extracellular ligand-gated ion channel activity
0.70	GO:0099600	transmembrane receptor activity
0.65	GO:0038023	signaling receptor activity

0.30

GO:0031224

intrinsic component of membrane

tr|T1FT39|T1FT39_HELRO
Uncharacterized protein
Search

tr|T1FT40|T1FT40_HELRO
Uncharacterized protein
Search

0.41	GO:0043412	macromolecule modification
0.41	GO:0065007	biological regulation
0.40	GO:0044260	cellular macromolecule metabolic process
0.40	GO:0090304	nucleic acid metabolic process
0.39	GO:0019538	protein metabolic process
0.39	GO:0036474	cell death in response to hydrogen peroxide
0.39	GO:0097468	programmed cell death in response to reactive oxygen species
0.39	GO:0034654	nucleobase-containing compound biosynthetic process
0.38	GO:0006325	chromatin organization
0.38	GO:0009059	macromolecule biosynthetic process

0.41	GO:0003676	nucleic acid binding
0.41	GO:0140096	catalytic activity, acting on a protein
0.39	GO:0016278	lysine N-methyltransferase activity
0.39	GO:0003721	telomerase RNA reverse transcriptase activity
0.39	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.39	GO:0046872	metal ion binding
0.39	GO:0001085	RNA polymerase II transcription factor binding
0.38	GO:0017137	Rab GTPase binding
0.38	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.38	GO:0005096	GTPase activator activity

0.41	GO:0005634	nucleus
0.39	GO:0032300	mismatch repair complex
0.38	GO:0012505	endomembrane system
0.37	GO:0005667	transcription factor complex
0.37	GO:0031251	PAN complex
0.36	GO:0070701	mucus layer
0.36	GO:0005773	vacuole
0.35	GO:0031514	motile cilium
0.34	GO:0031967	organelle envelope
0.34	GO:0031090	organelle membrane

0.39	EC:2.1.1	GO:0016278
0.36	KEGG:R02472	GO:0008677

tr|T1FT41|T1FT41_HELRO
Uncharacterized protein
Search

ACE

0.65	Angiotensin-converting enzyme

0.61	GO:0006508	proteolysis
0.40	GO:1903597	negative regulation of gap junction assembly
0.40	GO:0071838	cell proliferation in bone marrow
0.40	GO:2000170	positive regulation of peptidyl-cysteine S-nitrosylation
0.39	GO:1900086	positive regulation of peptidyl-tyrosine autophosphorylation
0.39	GO:0003084	positive regulation of systemic arterial blood pressure
0.39	GO:1902033	regulation of hematopoietic stem cell proliferation
0.38	GO:0002446	neutrophil mediated immunity
0.38	GO:0061098	positive regulation of protein tyrosine kinase activity
0.38	GO:0032092	positive regulation of protein binding

0.84	GO:0008241	peptidyl-dipeptidase activity
0.72	GO:0004180	carboxypeptidase activity
0.67	GO:0008237	metallopeptidase activity
0.54	GO:0046872	metal ion binding

0.35	GO:0005615	extracellular space
0.34	GO:0005886	plasma membrane
0.33	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.84

EC:3.4.15

GO:0008241

tr|T1FT42|T1FT42_HELRO
Uncharacterized protein
Search

0.65	GO:0006357	regulation of transcription by RNA polymerase II
0.50	GO:0001525	angiogenesis
0.38	GO:0016310	phosphorylation

0.57	GO:0003700	DNA binding transcription factor activity
0.51	GO:0043565	sequence-specific DNA binding
0.39	GO:0016301	kinase activity
0.37	GO:0046872	metal ion binding

0.51	GO:0005634	nucleus
0.45	GO:0005829	cytosol
0.45	GO:0043233	organelle lumen
0.41	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

tr|T1FT43|T1FT43_HELRO
Uncharacterized protein
Search

0.63	GO:0006468	protein phosphorylation
0.47	GO:0045035	sensory organ precursor cell division
0.47	GO:0035160	maintenance of epithelial integrity, open tracheal system
0.46	GO:0018209	peptidyl-serine modification
0.46	GO:0008407	chaeta morphogenesis
0.46	GO:0016322	neuron remodeling
0.45	GO:0007314	oocyte anterior/posterior axis specification
0.45	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.44	GO:0032456	endocytic recycling
0.44	GO:0001578	microtubule bundle formation

0.64	GO:0004672	protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0017137	Rab GTPase binding
0.35	GO:0005057	signal transducer activity, downstream of receptor
0.35	GO:0036435	K48-linked polyubiquitin modification-dependent protein binding
0.34	GO:0051219	phosphoprotein binding
0.34	GO:0031625	ubiquitin protein ligase binding

0.44	GO:0051286	cell tip
0.36	GO:0005737	cytoplasm
0.34	GO:0016235	aggresome
0.34	GO:0005654	nucleoplasm
0.33	GO:0031967	organelle envelope
0.33	GO:0031090	organelle membrane
0.32	GO:0005815	microtubule organizing center
0.32	GO:0005874	microtubule
0.30	GO:0016021	integral component of membrane

tr|T1FT44|T1FT44_HELRO
Uncharacterized protein
Search

tr|T1FT45|T1FT45_HELRO
Uncharacterized protein
Search

tr|T1FT46|T1FT46_HELRO
Uncharacterized protein
Search

tr|T1FT47|T1FT47_HELRO
Uncharacterized protein
Search

0.55	GO:0007411	axon guidance
0.54	GO:0038007	netrin-activated signaling pathway
0.50	GO:0006915	apoptotic process
0.46	GO:0007432	salivary gland boundary specification
0.45	GO:0070983	dendrite guidance
0.45	GO:0050773	regulation of dendrite development
0.44	GO:0008347	glial cell migration
0.44	GO:0008038	neuron recognition
0.43	GO:0048936	peripheral nervous system neuron axonogenesis
0.43	GO:0010769	regulation of cell morphogenesis involved in differentiation

0.54	GO:0005042	netrin receptor activity
0.40	GO:0019904	protein domain specific binding
0.34	GO:0043565	sequence-specific DNA binding
0.33	GO:0004713	protein tyrosine kinase activity
0.33	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.33	GO:0046914	transition metal ion binding
0.33	GO:0020037	heme binding
0.32	GO:0003700	DNA binding transcription factor activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding

0.44	GO:0030424	axon
0.43	GO:0043025	neuronal cell body
0.43	GO:0030425	dendrite
0.42	GO:0030426	growth cone
0.39	GO:0098595	perivitelline space
0.36	GO:0005886	plasma membrane
0.34	GO:0005829	cytosol
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.33

EC:2.7.10

GO:0004713

tr|T1FT48|T1FT48_HELRO
Uncharacterized protein
Search

tr|T1FT49|T1FT49_HELRO
Uncharacterized protein
Search

tr|T1FT50|T1FT50_HELRO
Uncharacterized protein
Search

tr|T1FT51|T1FT51_HELRO
Uncharacterized protein
Search

tr|T1FT52|T1FT52_HELRO
Uncharacterized protein
Search

0.47	GO:0043547	positive regulation of GTPase activity
0.45	GO:0046854	phosphatidylinositol phosphorylation
0.39	GO:0099120	socially cooperative development
0.38	GO:0006470	protein dephosphorylation
0.38	GO:0060079	excitatory postsynaptic potential
0.38	GO:0006325	chromatin organization
0.37	GO:0060255	regulation of macromolecule metabolic process
0.37	GO:0035235	ionotropic glutamate receptor signaling pathway
0.37	GO:0007017	microtubule-based process
0.36	GO:0006914	autophagy

0.48	GO:0046872	metal ion binding
0.47	GO:0016307	phosphatidylinositol phosphate kinase activity
0.47	GO:0005096	GTPase activator activity
0.39	GO:0140096	catalytic activity, acting on a protein
0.39	GO:0030554	adenyl nucleotide binding
0.39	GO:0030306	ADP-ribosylation factor binding
0.39	GO:0097367	carbohydrate derivative binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0008144	drug binding
0.38	GO:0016787	hydrolase activity

0.40	GO:0005634	nucleus
0.38	GO:0070013	intracellular organelle lumen
0.37	GO:0098794	postsynapse
0.37	GO:0030289	protein phosphatase 4 complex
0.37	GO:0030681	multimeric ribonuclease P complex
0.37	GO:0044446	intracellular organelle part
0.36	GO:0033202	DNA helicase complex
0.36	GO:0043232	intracellular non-membrane-bounded organelle
0.35	GO:1904949	ATPase complex
0.34	GO:0043234	protein complex

0.47

GO:0016307

tr|T1FT53|T1FT53_HELRO
Uncharacterized protein
Search

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.46	GO:0072137	condensed mesenchymal cell proliferation
0.45	GO:0010923	negative regulation of phosphatase activity
0.44	GO:0072006	nephron development
0.40	GO:0044331	cell-cell adhesion mediated by cadherin
0.38	GO:0045317	equator specification
0.38	GO:0090176	microtubule cytoskeleton organization involved in establishment of planar polarity
0.38	GO:0010631	epithelial cell migration
0.38	GO:0001737	establishment of imaginal disc-derived wing hair orientation
0.38	GO:0035159	regulation of tube length, open tracheal system

0.70	GO:0005509	calcium ion binding
0.41	GO:0005515	protein binding
0.36	GO:0004930	G-protein coupled receptor activity
0.35	GO:0004022	alcohol dehydrogenase (NAD) activity
0.34	GO:0004725	protein tyrosine phosphatase activity
0.34	GO:0030246	carbohydrate binding

0.56	GO:0005886	plasma membrane
0.38	GO:0005913	cell-cell adherens junction
0.36	GO:0089717	spanning component of membrane
0.35	GO:0005902	microvillus
0.35	GO:0005903	brush border
0.35	GO:0045177	apical part of cell
0.34	GO:0120038	plasma membrane bounded cell projection part

0.35

EC:1.1.1.1

GO:0004022

tr|T1FT54|T1FT54_HELRO
Uncharacterized protein
Search

tr|T1FT55|T1FT55_HELRO
Uncharacterized protein
Search

0.38	GO:0055085	transmembrane transport
0.38	GO:0032012	regulation of ARF protein signal transduction
0.38	GO:0006334	nucleosome assembly
0.37	GO:0015858	nucleoside transport
0.37	GO:0006508	proteolysis
0.36	GO:0006816	calcium ion transport
0.36	GO:0006281	DNA repair
0.36	GO:0065009	regulation of molecular function
0.36	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.35	GO:0006396	RNA processing

0.42	GO:0022829	wide pore channel activity
0.40	GO:0005515	protein binding
0.39	GO:0005509	calcium ion binding
0.37	GO:0003676	nucleic acid binding
0.37	GO:0005337	nucleoside transmembrane transporter activity
0.36	GO:0098772	molecular function regulator
0.36	GO:0004519	endonuclease activity
0.35	GO:0004930	G-protein coupled receptor activity
0.35	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors
0.34	GO:0020037	heme binding

0.39	GO:0000785	chromatin
0.37	GO:0044815	DNA packaging complex
0.37	GO:0097458	neuron part
0.37	GO:0005634	nucleus
0.37	GO:0032993	protein-DNA complex
0.36	GO:0031974	membrane-enclosed lumen
0.36	GO:1904949	ATPase complex
0.34	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:1.3

GO:0016627

tr|T1FT56|T1FT56_HELRO
Uncharacterized protein
Search

tr|T1FT57|T1FT57_HELRO
Uncharacterized protein
Search

0.46	GO:0005975	carbohydrate metabolic process
0.45	GO:0016310	phosphorylation
0.41	GO:0009057	macromolecule catabolic process
0.40	GO:0071554	cell wall organization or biogenesis
0.39	GO:0032501	multicellular organismal process
0.39	GO:0034477	U6 snRNA 3'-end processing
0.38	GO:0045229	external encapsulating structure organization
0.38	GO:0030154	cell differentiation
0.38	GO:0006464	cellular protein modification process
0.38	GO:0090305	nucleic acid phosphodiester bond hydrolysis

0.58	GO:0000829	inositol heptakisphosphate kinase activity
0.53	GO:0030248	cellulose binding
0.44	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.40	GO:0016788	hydrolase activity, acting on ester bonds
0.38	GO:0140096	catalytic activity, acting on a protein
0.37	GO:0035091	phosphatidylinositol binding
0.37	GO:0008061	chitin binding
0.37	GO:0008270	zinc ion binding
0.37	GO:0003777	microtubule motor activity
0.37	GO:0019213	deacetylase activity

0.48	GO:0005576	extracellular region
0.40	GO:0005634	nucleus
0.38	GO:0031974	membrane-enclosed lumen
0.37	GO:1902494	catalytic complex
0.37	GO:0005618	cell wall
0.36	GO:0044427	chromosomal part
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.44

GO:0004553

tr|T1FT58|T1FT58_HELRO
Uncharacterized protein
Search

0.73	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.61	GO:0043547	positive regulation of GTPase activity
0.52	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway
0.41	GO:0009968	negative regulation of signal transduction
0.37	GO:0006914	autophagy
0.36	GO:0006438	valyl-tRNA aminoacylation
0.35	GO:0007264	small GTPase mediated signal transduction
0.35	GO:0031018	endocrine pancreas development
0.35	GO:0048699	generation of neurons
0.35	GO:0000902	cell morphogenesis

0.72	GO:0001965	G-protein alpha-subunit binding
0.61	GO:0005096	GTPase activator activity
0.36	GO:0004832	valine-tRNA ligase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0002161	aminoacyl-tRNA editing activity
0.33	GO:0005509	calcium ion binding
0.33	GO:1990380	Lys48-specific deubiquitinase activity
0.33	GO:0005089	Rho guanyl-nucleotide exchange factor activity

0.46	GO:0031410	cytoplasmic vesicle
0.45	GO:0005829	cytosol
0.42	GO:0005634	nucleus
0.42	GO:0005886	plasma membrane
0.39	GO:0005903	brush border
0.39	GO:0045121	membrane raft
0.38	GO:0043197	dendritic spine
0.38	GO:0043679	axon terminus
0.38	GO:0043025	neuronal cell body
0.36	GO:0005794	Golgi apparatus

0.36	EC:6.1.1.9	GO:0004832
0.36	KEGG:R03665	GO:0004832

tr|T1FT59|T1FT59_HELRO
Uncharacterized protein
Search

tr|T1FT60|T1FT60_HELRO
Uncharacterized protein
Search

tr|T1FT61|T1FT61_HELRO
Uncharacterized protein
Search

tr|T1FT62|T1FT62_HELRO
Uncharacterized protein
Search

0.66	GO:0030001	metal ion transport
0.55	GO:0055085	transmembrane transport
0.41	GO:0072511	divalent inorganic cation transport
0.36	GO:0051382	kinetochore assembly
0.34	GO:0006414	translational elongation
0.33	GO:0032259	methylation

0.69	GO:0046873	metal ion transmembrane transporter activity
0.42	GO:0072509	divalent inorganic cation transmembrane transporter activity
0.34	GO:0003746	translation elongation factor activity
0.34	GO:0003924	GTPase activity
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0019001	guanyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0008168	methyltransferase activity
0.33	GO:0030554	adenyl nucleotide binding

0.36	GO:0005886	plasma membrane
0.35	GO:0000776	kinetochore
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0008168

tr|T1FT63|T1FT63_HELRO
Uncharacterized protein
Search

tr|T1FT64|T1FT64_HELRO
Uncharacterized protein
Search

0.74	GO:0014029	neural crest formation
0.74	GO:0007000	nucleolus organization
0.71	GO:0014032	neural crest cell development
0.61	GO:0006417	regulation of translation
0.51	GO:0048701	embryonic cranial skeleton morphogenesis
0.45	GO:0033979	box H/ACA snoRNA metabolic process
0.43	GO:0042306	regulation of protein import into nucleus
0.42	GO:0006970	response to osmotic stress
0.42	GO:0008284	positive regulation of cell proliferation
0.42	GO:0048167	regulation of synaptic plasticity

0.76	GO:0001042	RNA polymerase I core binding
0.63	GO:0046982	protein heterodimerization activity
0.45	GO:0034512	box C/D snoRNA binding
0.45	GO:0034513	box H/ACA snoRNA binding
0.44	GO:0032550	purine ribonucleoside binding
0.44	GO:0019001	guanyl nucleotide binding
0.44	GO:0008139	nuclear localization sequence binding
0.43	GO:0016758	transferase activity, transferring hexosyl groups
0.41	GO:0019904	protein domain specific binding
0.41	GO:0008134	transcription factor binding

0.72	GO:0015030	Cajal body
0.67	GO:0001650	fibrillar center
0.44	GO:0031428	box C/D snoRNP complex
0.43	GO:0031429	box H/ACA snoRNP complex
0.36	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.43

EC:2.4.1

GO:0016758

tr|T1FT65|T1FT65_HELRO
Uncharacterized protein
Search

0.47	GO:0030514	negative regulation of BMP signaling pathway
0.46	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway
0.43	GO:0016567	protein ubiquitination
0.37	GO:0018108	peptidyl-tyrosine phosphorylation
0.35	GO:0060215	primitive hemopoiesis
0.35	GO:0030099	myeloid cell differentiation
0.34	GO:0035166	post-embryonic hemopoiesis
0.34	GO:0033333	fin development
0.34	GO:0048066	developmental pigmentation
0.34	GO:0034101	erythrocyte homeostasis

0.62	GO:0008270	zinc ion binding
0.48	GO:0070410	co-SMAD binding
0.48	GO:0070412	R-SMAD binding
0.44	GO:0016874	ligase activity
0.38	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0003677	DNA binding

0.44	GO:0005622	intracellular
0.38	GO:0043227	membrane-bounded organelle
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0044422	organelle part
0.30	GO:0016020	membrane

0.44	EC:6	GO:0016874
0.33	KEGG:R03876	GO:0004842

tr|T1FT66|T1FT66_HELRO
Uncharacterized protein
Search

tr|T1FT67|T1FT67_HELRO
Uncharacterized protein
Search

PI4K2B

0.85	Phosphatidylinositol 4-kinase type-ii

0.56	GO:0016310	phosphorylation
0.51	GO:0007032	endosome organization
0.50	GO:0007030	Golgi organization
0.47	GO:0046488	phosphatidylinositol metabolic process
0.47	GO:0030258	lipid modification
0.38	GO:0007005	mitochondrion organization
0.36	GO:0033339	pectoral fin development
0.34	GO:0046474	glycerophospholipid biosynthetic process
0.34	GO:0006352	DNA-templated transcription, initiation

0.58	GO:0016301	kinase activity
0.43	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.37	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding

0.49	GO:0005765	lysosomal membrane
0.49	GO:0005802	trans-Golgi network
0.47	GO:0005768	endosome
0.40	GO:0005886	plasma membrane
0.39	GO:0031305	integral component of mitochondrial inner membrane
0.34	GO:0005829	cytosol
0.33	GO:0005634	nucleus

0.43

GO:0016773

tr|T1FT68|T1FT68_HELRO
Uncharacterized protein
Search

0.60	Transcription initiation factor TFIID subunit 7

0.79	GO:0006367	transcription initiation from RNA polymerase II promoter
0.58	GO:0006413	translational initiation
0.47	GO:0070897	DNA-templated transcriptional preinitiation complex assembly
0.46	GO:0006357	regulation of transcription by RNA polymerase II
0.46	GO:0035067	negative regulation of histone acetylation
0.44	GO:0006469	negative regulation of protein kinase activity
0.44	GO:0030520	intracellular estrogen receptor signaling pathway
0.42	GO:0045893	positive regulation of transcription, DNA-templated
0.42	GO:0045892	negative regulation of transcription, DNA-templated
0.35	GO:0007283	spermatogenesis

0.58	GO:0003743	translation initiation factor activity
0.54	GO:0035035	histone acetyltransferase binding
0.50	GO:0003713	transcription coactivator activity
0.49	GO:0044212	transcription regulatory region DNA binding
0.48	GO:0061628	H3K27me3 modified histone binding
0.47	GO:0042809	vitamin D receptor binding
0.47	GO:0046966	thyroid hormone receptor binding
0.42	GO:0046982	protein heterodimerization activity
0.39	GO:0003700	DNA binding transcription factor activity
0.34	GO:0004449	isocitrate dehydrogenase (NAD+) activity

0.80	GO:0005669	transcription factor TFIID complex
0.46	GO:0033276	transcription factor TFTC complex
0.46	GO:0008024	cyclin/CDK positive transcription elongation factor complex
0.45	GO:0071339	MLL1 complex
0.42	GO:0005794	Golgi apparatus
0.35	GO:0005921	gap junction
0.33	GO:0010369	chromocenter
0.33	GO:0005886	plasma membrane
0.32	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

0.34

EC:1.1.1.41

GO:0004449

tr|T1FT69|T1FT69_HELRO
Uncharacterized protein
Search

0.45	GO:1902877	positive regulation of embryonic pattern specification
0.45	GO:0014881	regulation of myofibril size
0.44	GO:1904582	positive regulation of intracellular mRNA localization
0.44	GO:0071689	muscle thin filament assembly
0.44	GO:0007279	pole cell formation
0.44	GO:0060282	positive regulation of oocyte development
0.44	GO:1903431	positive regulation of cell maturation
0.44	GO:0007317	regulation of pole plasm oskar mRNA localization
0.43	GO:0007291	sperm individualization
0.42	GO:0045214	sarcomere organization

0.53	GO:0046872	metal ion binding
0.40	GO:0003779	actin binding

0.44	GO:0070864	sperm individualization complex
0.43	GO:0031672	A band
0.42	GO:0030018	Z disc
0.42	GO:0005925	focal adhesion
0.35	GO:0055120	striated muscle dense body
0.34	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|T1FT70|T1FT70_HELRO
Uncharacterized protein
Search

0.44	GO:0043326	chemotaxis to folate
0.44	GO:0060176	regulation of aggregation involved in sorocarp development
0.43	GO:0043327	chemotaxis to cAMP
0.43	GO:0031272	regulation of pseudopodium assembly
0.42	GO:0006661	phosphatidylinositol biosynthetic process
0.41	GO:0006468	protein phosphorylation
0.41	GO:0030010	establishment of cell polarity
0.41	GO:0030837	negative regulation of actin filament polymerization
0.40	GO:0099120	socially cooperative development
0.40	GO:0043951	negative regulation of cAMP-mediated signaling

0.42	GO:0140096	catalytic activity, acting on a protein
0.41	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.41	GO:0004629	phospholipase C activity
0.40	GO:0016301	kinase activity
0.40	GO:0017076	purine nucleotide binding
0.40	GO:0097367	carbohydrate derivative binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0003676	nucleic acid binding
0.39	GO:0016409	palmitoyltransferase activity
0.39	GO:0046872	metal ion binding

0.44	GO:0070772	PAS complex
0.42	GO:0005881	cytoplasmic microtubule
0.40	GO:0005815	microtubule organizing center
0.39	GO:0000792	heterochromatin
0.39	GO:0005634	nucleus
0.38	GO:0030687	preribosome, large subunit precursor
0.37	GO:0005795	Golgi stack
0.34	GO:0005739	mitochondrion
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.41

GO:0016773

tr|T1FT71|T1FT71_HELRO
Uncharacterized protein
Search

0.45	GO:0006396	RNA processing
0.43	GO:0016570	histone modification
0.43	GO:0018205	peptidyl-lysine modification
0.41	GO:0060255	regulation of macromolecule metabolic process
0.41	GO:0031323	regulation of cellular metabolic process
0.41	GO:0051171	regulation of nitrogen compound metabolic process
0.41	GO:0080090	regulation of primary metabolic process
0.40	GO:0009889	regulation of biosynthetic process
0.40	GO:0006475	internal protein amino acid acetylation
0.39	GO:0006479	protein methylation

0.47	GO:0004386	helicase activity
0.45	GO:0003676	nucleic acid binding
0.42	GO:0030554	adenyl nucleotide binding
0.42	GO:0097367	carbohydrate derivative binding
0.42	GO:0008144	drug binding
0.42	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.42	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0004402	histone acetyltransferase activity
0.39	GO:0003700	DNA binding transcription factor activity
0.39	GO:0046872	metal ion binding

0.42	GO:0005654	nucleoplasm
0.40	GO:1990234	transferase complex
0.38	GO:0043234	protein complex
0.35	GO:0015630	microtubule cytoskeleton
0.35	GO:0044430	cytoskeletal part
0.35	GO:0005576	extracellular region
0.34	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.40

GO:0004402

tr|T1FT72|T1FT72_HELRO
Uncharacterized protein
Search

tr|T1FT73|T1FT73_HELRO
Uncharacterized protein
Search

0.51

GO:0007304

chorion-containing eggshell formation

0.30

GO:0003824

catalytic activity

0.43	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

tr|T1FT74|T1FT74_HELRO
Uncharacterized protein
Search

tr|T1FT75|T1FT75_HELRO
Uncharacterized protein
Search

0.63	GO:0006468	protein phosphorylation
0.49	GO:0035556	intracellular signal transduction
0.40	GO:0051726	regulation of cell cycle
0.39	GO:0000749	response to pheromone involved in conjugation with cellular fusion
0.39	GO:0032005	signal transduction involved in conjugation with cellular fusion
0.37	GO:0022402	cell cycle process
0.37	GO:0051781	positive regulation of cell division
0.37	GO:0001403	invasive growth in response to glucose limitation
0.37	GO:0001402	signal transduction involved in filamentous growth
0.37	GO:0051130	positive regulation of cellular component organization

0.64	GO:0004672	protein kinase activity
0.58	GO:0005057	signal transducer activity, downstream of receptor
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.35	GO:0060089	molecular transducer activity
0.35	GO:0008134	transcription factor binding
0.33	GO:0042802	identical protein binding
0.33	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity

0.39	GO:0005622	intracellular
0.36	GO:0030427	site of polarized growth
0.36	GO:0043227	membrane-bounded organelle
0.36	GO:0005933	cellular bud
0.34	GO:1902554	serine/threonine protein kinase complex
0.34	GO:0043228	non-membrane-bounded organelle
0.34	GO:0005937	mating projection
0.33	GO:0120038	plasma membrane bounded cell projection part
0.33	GO:0044422	organelle part
0.32	GO:0043234	protein complex

0.33

EC:1.1.1.44

GO:0004616

tr|T1FT76|T1FT76_HELRO
Uncharacterized protein
Search

0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.50	GO:1903898	negative regulation of PERK-mediated unfolded protein response
0.49	GO:1902202	regulation of hepatocyte growth factor receptor signaling pathway
0.49	GO:0035791	platelet-derived growth factor receptor-beta signaling pathway
0.49	GO:2000646	positive regulation of receptor catabolic process
0.49	GO:0036498	IRE1-mediated unfolded protein response
0.48	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
0.48	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway
0.48	GO:0007257	activation of JUN kinase activity
0.47	GO:0008286	insulin receptor signaling pathway

0.75	GO:0004725	protein tyrosine phosphatase activity
0.47	GO:0046875	ephrin receptor binding
0.47	GO:0045296	cadherin binding
0.47	GO:0030971	receptor tyrosine kinase binding
0.40	GO:0008270	zinc ion binding
0.40	GO:0045295	gamma-catenin binding
0.39	GO:0008013	beta-catenin binding
0.39	GO:0070097	delta-catenin binding
0.38	GO:0005158	insulin receptor binding
0.38	GO:0051721	protein phosphatase 2A binding

0.49	GO:0097443	sorting endosome
0.48	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane
0.46	GO:0005769	early endosome
0.38	GO:0005886	plasma membrane
0.38	GO:0005856	cytoskeleton
0.36	GO:0005829	cytosol
0.35	GO:0005911	cell-cell junction
0.35	GO:0001750	photoreceptor outer segment
0.34	GO:0043025	neuronal cell body
0.34	GO:0030425	dendrite

0.75

GO:0004725

tr|T1FT77|T1FT77_HELRO
Uncharacterized protein
Search

tr|T1FT78|T1FT78_HELRO
Uncharacterized protein
Search

0.40	GO:1900189	positive regulation of cell adhesion involved in single-species biofilm formation
0.40	GO:0044011	single-species biofilm formation on inanimate substrate
0.39	GO:0071280	cellular response to copper ion
0.38	GO:0035690	cellular response to drug
0.37	GO:0005975	carbohydrate metabolic process
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:0010468	regulation of gene expression
0.36	GO:0009057	macromolecule catabolic process

0.38	GO:0008061	chitin binding
0.38	GO:0030248	cellulose binding
0.37	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.37	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.36	GO:0043565	sequence-specific DNA binding
0.36	GO:0046872	metal ion binding
0.35	GO:0016829	lyase activity

0.37	GO:0005634	nucleus
0.36	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.37

GO:0004553

tr|T1FT79|T1FT79_HELRO
Uncharacterized protein
Search

0.52	GO:0051569	regulation of histone H3-K4 methylation
0.49	GO:0030097	hemopoiesis
0.44	GO:2001141	regulation of RNA biosynthetic process
0.44	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.44	GO:0010468	regulation of gene expression
0.35	GO:2000219	positive regulation of invasive growth in response to glucose limitation
0.34	GO:0048519	negative regulation of biological process
0.34	GO:0097659	nucleic acid-templated transcription
0.34	GO:0070202	regulation of establishment of protein localization to chromosome
0.34	GO:0010467	gene expression

0.49	GO:0003676	nucleic acid binding
0.40	GO:0008270	zinc ion binding
0.36	GO:0140110	transcription regulator activity
0.35	GO:0005044	scavenger receptor activity
0.35	GO:0001095	TFIIE-class transcription factor binding
0.34	GO:0001097	TFIIH-class transcription factor binding
0.34	GO:0005328	neurotransmitter:sodium symporter activity
0.34	GO:0001102	RNA polymerase II activating transcription factor binding
0.33	GO:0004630	phospholipase D activity
0.33	GO:0015185	gamma-aminobutyric acid transmembrane transporter activity

0.40	GO:0005634	nucleus
0.34	GO:0044165	host cell endoplasmic reticulum
0.33	GO:1990234	transferase complex
0.33	GO:0005667	transcription factor complex
0.33	GO:0033644	host cell membrane
0.33	GO:0044446	intracellular organelle part
0.33	GO:0043005	neuron projection
0.33	GO:0031251	PAN complex
0.33	GO:0099512	supramolecular fiber
0.33	GO:0015630	microtubule cytoskeleton

0.33

EC:3.1.4.4

GO:0004630

tr|T1FT80|T1FT80_HELRO
Uncharacterized protein
Search

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.54	GO:0007399	nervous system development
0.52	GO:0048513	animal organ development
0.51	GO:0007605	sensory perception of sound
0.51	GO:0007626	locomotory behavior
0.49	GO:0120036	plasma membrane bounded cell projection organization
0.49	GO:0048468	cell development
0.43	GO:0010631	epithelial cell migration
0.43	GO:0060322	head development
0.41	GO:0007267	cell-cell signaling

0.70	GO:0005509	calcium ion binding
0.38	GO:0004664	prephenate dehydratase activity
0.35	GO:0050839	cell adhesion molecule binding
0.34	GO:0032403	protein complex binding

0.53	GO:0005886	plasma membrane
0.53	GO:0032420	stereocilium
0.42	GO:0005912	adherens junction
0.40	GO:0005911	cell-cell junction
0.36	GO:0031254	cell trailing edge
0.35	GO:0045178	basal part of cell
0.35	GO:0030055	cell-substrate junction
0.30	GO:0016021	integral component of membrane

0.38

EC:4.2.1.51

GO:0004664

tr|T1FT81|T1FT81_HELRO
Uncharacterized protein
Search

tr|T1FT82|T1FT82_HELRO
Uncharacterized protein
Search

0.48	THO complex subunit 2 (Fragment)

0.78	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.74	GO:0051028	mRNA transport
0.73	GO:0006405	RNA export from nucleus
0.65	GO:0046784	viral mRNA export from host cell nucleus
0.57	GO:0048666	neuron development
0.52	GO:0010467	gene expression
0.48	GO:0010793	regulation of mRNA export from nucleus
0.47	GO:0001824	blastocyst development
0.47	GO:0017145	stem cell division
0.47	GO:0010977	negative regulation of neuron projection development

0.70	GO:0003729	mRNA binding
0.42	GO:0008270	zinc ion binding
0.40	GO:0005515	protein binding

0.82	GO:0000445	THO complex part of transcription export complex
0.59	GO:0000784	nuclear chromosome, telomeric region
0.46	GO:0016607	nuclear speck

tr|T1FT83|T1FT83_HELRO
Palmitoyltransferase
Search

ZDHHC6

0.54	Palmitoyltransferase

0.54	GO:0018345	protein palmitoylation
0.34	GO:0071108	protein K48-linked deubiquitination
0.33	GO:0006606	protein import into nucleus
0.32	GO:0055114	oxidation-reduction process

0.79	GO:0019706	protein-cysteine S-palmitoyltransferase activity
0.34	GO:1990380	Lys48-specific deubiquitinase activity
0.34	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.34	GO:0061608	nuclear import signal receptor activity
0.33	GO:0005515	protein binding
0.33	GO:0008565	protein transporter activity
0.32	GO:0016491	oxidoreductase activity
0.32	GO:0046872	metal ion binding
0.32	GO:0003676	nucleic acid binding

0.47	GO:0005783	endoplasmic reticulum
0.39	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.38	GO:0031984	organelle subcompartment
0.32	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.79

EC:2.3.1.225

GO:0019706

tr|T1FT84|T1FT84_HELRO
Uncharacterized protein
Search

0.40	GO:0051276	chromosome organization
0.40	GO:0000724	double-strand break repair via homologous recombination
0.37	GO:0006260	DNA replication
0.35	GO:1903506	regulation of nucleic acid-templated transcription
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression

0.40	GO:0043140	ATP-dependent 3'-5' DNA helicase activity
0.40	GO:0009378	four-way junction helicase activity
0.36	GO:0003700	DNA binding transcription factor activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0003677	DNA binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.38	GO:0005694	chromosome
0.37	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|T1FT85|T1FT85_HELRO
Uncharacterized protein
Search

0.77	GO:0070588	calcium ion transmembrane transport
0.53	GO:0014051	gamma-aminobutyric acid secretion
0.52	GO:0070509	calcium ion import
0.50	GO:0048709	oligodendrocyte differentiation
0.45	GO:0006828	manganese ion transport
0.45	GO:0051480	regulation of cytosolic calcium ion concentration
0.34	GO:0051924	regulation of calcium ion transport
0.34	GO:0007338	single fertilization

0.79	GO:0005262	calcium channel activity
0.51	GO:0008013	beta-catenin binding
0.51	GO:0045296	cadherin binding
0.50	GO:0070679	inositol 1,4,5 trisphosphate binding
0.33	GO:0005509	calcium ion binding

0.51	GO:0016323	basolateral plasma membrane
0.50	GO:0034704	calcium channel complex
0.50	GO:0030863	cortical cytoskeleton
0.50	GO:0005901	caveola
0.49	GO:0005911	cell-cell junction
0.48	GO:0009986	cell surface
0.41	GO:0043234	protein complex
0.41	GO:0005887	integral component of plasma membrane

tr|T1FT86|T1FT86_HELRO
Uncharacterized protein
Search

0.45	GO:0046854	phosphatidylinositol phosphorylation
0.45	GO:0050794	regulation of cellular process
0.44	GO:0010556	regulation of macromolecule biosynthetic process
0.44	GO:0010468	regulation of gene expression
0.44	GO:0051171	regulation of nitrogen compound metabolic process
0.44	GO:0080090	regulation of primary metabolic process
0.42	GO:0043547	positive regulation of GTPase activity
0.41	GO:0023052	signaling
0.41	GO:0007154	cell communication
0.41	GO:0051716	cellular response to stimulus

0.48	GO:0005509	calcium ion binding
0.46	GO:0016307	phosphatidylinositol phosphate kinase activity
0.46	GO:0003700	DNA binding transcription factor activity
0.42	GO:0005096	GTPase activator activity
0.39	GO:0003677	DNA binding
0.39	GO:0008270	zinc ion binding
0.39	GO:0030306	ADP-ribosylation factor binding
0.38	GO:0030554	adenyl nucleotide binding
0.38	GO:0043168	anion binding
0.38	GO:0032555	purine ribonucleotide binding

0.42	GO:0005634	nucleus
0.38	GO:0070864	sperm individualization complex
0.38	GO:0036375	Kibra-Ex-Mer complex
0.37	GO:0031672	A band
0.37	GO:0030018	Z disc
0.37	GO:0034707	chloride channel complex
0.36	GO:0005925	focal adhesion
0.36	GO:0016324	apical plasma membrane
0.36	GO:0005783	endoplasmic reticulum
0.35	GO:0019028	viral capsid

0.46	EC:2.7.1	GO:0016307
0.37	KEGG:R05982 KEGG:R06722	GO:0004571

tr|T1FT87|T1FT87_HELRO
Uncharacterized protein
Search

0.78	GO:0007040	lysosome organization
0.51	GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway
0.50	GO:0042267	natural killer cell mediated cytotoxicity
0.48	GO:0043473	pigmentation
0.38	GO:0033364	mast cell secretory granule organization
0.37	GO:0042832	defense response to protozoan
0.37	GO:0030595	leukocyte chemotaxis
0.36	GO:0033299	secretion of lysosomal enzymes
0.36	GO:0055091	phospholipid homeostasis
0.36	GO:0032816	positive regulation of natural killer cell activation

0.35	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding
0.32	GO:0016301	kinase activity

0.44	GO:0015630	microtubule cytoskeleton
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

tr|T1FT88|T1FT88_HELRO
Uncharacterized protein
Search

tr|T1FT89|T1FT89_HELRO
Uncharacterized protein
Search

0.54

GO:0046872

metal ion binding

tr|T1FT90|T1FT90_HELRO
Uncharacterized protein
Search

LOC108280551

0.81	Alternative splicing factor

0.47	GO:0019068	virion assembly
0.42	GO:0006310	DNA recombination
0.41	GO:0006260	DNA replication
0.41	GO:0006974	cellular response to DNA damage stimulus
0.39	GO:0044826	viral genome integration into host DNA
0.39	GO:0075713	establishment of integrated proviral latency
0.39	GO:0015074	DNA integration
0.38	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.38	GO:0006278	RNA-dependent DNA biosynthetic process
0.37	GO:0051806	entry into cell of other organism involved in symbiotic interaction

0.63	GO:0008270	zinc ion binding
0.55	GO:0003723	RNA binding
0.43	GO:0005198	structural molecule activity
0.39	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.39	GO:0003677	DNA binding
0.39	GO:0070001	aspartic-type peptidase activity
0.38	GO:0003964	RNA-directed DNA polymerase activity
0.38	GO:0004175	endopeptidase activity
0.34	GO:0003887	DNA-directed DNA polymerase activity
0.33	GO:0036402	proteasome-activating ATPase activity

0.45	GO:0019028	viral capsid
0.40	GO:0005634	nucleus
0.39	GO:0072494	host multivesicular body
0.37	GO:0020002	host cell plasma membrane
0.37	GO:0044185	host cell late endosome membrane
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.31	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.39

EC:3.1.26.4

GO:0004523

tr|T1FT91|T1FT91_HELRO
Uncharacterized protein
Search

0.72	GO:0031175	neuron projection development
0.52	GO:0031113	regulation of microtubule polymerization
0.48	GO:0000226	microtubule cytoskeleton organization
0.47	GO:0045218	zonula adherens maintenance
0.46	GO:1903358	regulation of Golgi organization
0.46	GO:0045198	establishment of epithelial cell apical/basal polarity
0.46	GO:0090136	epithelial cell-cell adhesion
0.45	GO:0090109	regulation of cell-substrate junction assembly
0.45	GO:1903391	regulation of adherens junction organization
0.45	GO:0030952	establishment or maintenance of cytoskeleton polarity

0.79	GO:0005516	calmodulin binding
0.79	GO:0030507	spectrin binding
0.74	GO:0008017	microtubule binding
0.43	GO:0051015	actin filament binding
0.36	GO:0004852	uroporphyrinogen-III synthase activity
0.35	GO:0016303	1-phosphatidylinositol-3-kinase activity
0.34	GO:0004622	lysophospholipase activity

0.73	GO:0005874	microtubule
0.46	GO:0005915	zonula adherens
0.43	GO:0005813	centrosome
0.35	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.36	EC:4.2.1.75	GO:0004852
0.36	KEGG:R03165	GO:0004852

tr|T1FT92|T1FT92_HELRO
Uncharacterized protein
Search

tr|T1FT93|T1FT93_HELRO
Uncharacterized protein
Search

tr|T1FT94|T1FT94_HELRO
Phosphodiesterase
Search

0.21	Phosphodiesterase

0.60	GO:0007165	signal transduction
0.58	GO:0006198	cAMP catabolic process
0.54	GO:0060282	positive regulation of oocyte development
0.54	GO:0071321	cellular response to cGMP
0.54	GO:0043117	positive regulation of vascular permeability
0.54	GO:0043116	negative regulation of vascular permeability
0.53	GO:0001556	oocyte maturation
0.51	GO:0040020	regulation of meiotic nuclear division
0.50	GO:0071560	cellular response to transforming growth factor beta stimulus
0.49	GO:0050995	negative regulation of lipid catabolic process

0.78	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.53	GO:0046872	metal ion binding
0.39	GO:0030552	cAMP binding
0.33	GO:0005515	protein binding

0.48	GO:0032045	guanyl-nucleotide exchange factor complex
0.45	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.78

EC:3.1.4.17

GO:0004114

tr|T1FT95|T1FT95_HELRO
Uncharacterized protein
Search

tr|T1FT96|T1FT96_HELRO
Uncharacterized protein
Search

tr|T1FT97|T1FT97_HELRO
Uncharacterized protein
Search

tr|T1FT98|T1FT98_HELRO
Uncharacterized protein
Search

tr|T1FT99|T1FT99_HELRO
Uncharacterized protein
Search

0.48	GO:0016055	Wnt signaling pathway
0.46	GO:0030238	male sex determination
0.44	GO:0007548	sex differentiation
0.42	GO:0030154	cell differentiation
0.38	GO:2001141	regulation of RNA biosynthetic process
0.38	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.38	GO:0010468	regulation of gene expression
0.38	GO:0006351	transcription, DNA-templated
0.36	GO:0060767	epithelial cell proliferation involved in prostate gland development
0.35	GO:0060784	regulation of cell proliferation involved in tissue homeostasis

0.55	GO:0003677	DNA binding
0.43	GO:0005516	calmodulin binding
0.40	GO:0003700	DNA binding transcription factor activity
0.35	GO:0097157	pre-mRNA intronic binding
0.35	GO:0034236	protein kinase A catalytic subunit binding
0.35	GO:0008013	beta-catenin binding
0.34	GO:0004602	glutathione peroxidase activity
0.34	GO:0003682	chromatin binding
0.34	GO:0001067	regulatory region nucleic acid binding
0.34	GO:0046982	protein heterodimerization activity

0.61	GO:0005634	nucleus
0.41	GO:0070013	intracellular organelle lumen
0.38	GO:0044446	intracellular organelle part
0.34	GO:0005667	transcription factor complex
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.34

EC:1.11.1.9

GO:0004602

tr|T1FTA0|T1FTA0_HELRO
Uncharacterized protein
Search

tr|T1FTA1|T1FTA1_HELRO
Uncharacterized protein
Search

0.38

GO:0006352

DNA-templated transcription, initiation

0.39	GO:0046982	protein heterodimerization activity
0.36	GO:0003723	RNA binding

0.41	GO:0046695	SLIK (SAGA-like) complex
0.40	GO:0000124	SAGA complex
0.40	GO:0005669	transcription factor TFIID complex
0.30	GO:0044425	membrane part

tr|T1FTA2|T1FTA2_HELRO
Uncharacterized protein
Search

tr|T1FTA3|T1FTA3_HELRO
Uncharacterized protein
Search

tr|T1FTA4|T1FTA4_HELRO
Uncharacterized protein
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tr|T1FTA5|T1FTA5_HELRO
Uncharacterized protein
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tr|T1FTA6|T1FTA6_HELRO
Uncharacterized protein
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tr|T1FTA7|T1FTA7_HELRO
Uncharacterized protein
Search

tr|T1FTA8|T1FTA8_HELRO
Uncharacterized protein
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tr|T1FTA9|T1FTA9_HELRO
Uncharacterized protein
Search

0.64	GO:0051865	protein autoubiquitination
0.57	GO:0045893	positive regulation of transcription, DNA-templated
0.45	GO:0010626	negative regulation of Schwann cell proliferation
0.44	GO:0031643	positive regulation of myelination
0.39	GO:0006357	regulation of transcription by RNA polymerase II
0.36	GO:0006351	transcription, DNA-templated

0.57	GO:0004842	ubiquitin-protein transferase activity
0.50	GO:0046872	metal ion binding
0.40	GO:0044212	transcription regulatory region DNA binding
0.34	GO:0005515	protein binding
0.34	GO:0016874	ligase activity

0.42	GO:0005737	cytoplasm
0.38	GO:0005634	nucleus

0.34	EC:6	GO:0016874
0.57	KEGG:R03876	GO:0004842

tr|T1FTB0|T1FTB0_HELRO
Uncharacterized protein
Search

tr|T1FTB1|T1FTB1_HELRO
Uncharacterized protein
Search

tr|T1FTB2|T1FTB2_HELRO
Uncharacterized protein
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tr|T1FTB3|T1FTB3_HELRO
Uncharacterized protein
Search

0.43	GO:0006898	receptor-mediated endocytosis
0.40	GO:0042953	lipoprotein transport
0.37	GO:0007160	cell-matrix adhesion
0.36	GO:0006030	chitin metabolic process
0.36	GO:1905899	regulation of smooth muscle tissue development
0.35	GO:0003151	outflow tract morphogenesis
0.35	GO:0003208	cardiac ventricle morphogenesis
0.35	GO:0005975	carbohydrate metabolic process
0.35	GO:0008203	cholesterol metabolic process
0.34	GO:0006508	proteolysis

0.69	GO:0005509	calcium ion binding
0.45	GO:0005201	extracellular matrix structural constituent
0.42	GO:0005044	scavenger receptor activity
0.39	GO:0042803	protein homodimerization activity
0.36	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.36	GO:0008061	chitin binding
0.35	GO:0017056	structural constituent of nuclear pore
0.35	GO:0004175	endopeptidase activity
0.34	GO:0004930	G-protein coupled receptor activity
0.34	GO:0008237	metallopeptidase activity

0.44	GO:0044421	extracellular region part
0.42	GO:0005903	brush border
0.41	GO:0016324	apical plasma membrane
0.40	GO:0030139	endocytic vesicle
0.40	GO:0005905	clathrin-coated pit
0.40	GO:0005768	endosome
0.38	GO:0005794	Golgi apparatus
0.38	GO:0005783	endoplasmic reticulum
0.35	GO:0031253	cell projection membrane
0.35	GO:0005765	lysosomal membrane

0.36

GO:0004553

tr|T1FTB4|T1FTB4_HELRO
Uncharacterized protein
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tr|T1FTB5|T1FTB5_HELRO
Uncharacterized protein
Search

0.76	GO:0010951	negative regulation of endopeptidase activity
0.40	GO:0009620	response to fungus
0.39	GO:0006030	chitin metabolic process
0.38	GO:0001889	liver development
0.36	GO:0032504	multicellular organism reproduction
0.34	GO:0072675	osteoclast fusion
0.34	GO:0010839	negative regulation of keratinocyte proliferation
0.34	GO:0045616	regulation of keratinocyte differentiation
0.34	GO:0001942	hair follicle development
0.34	GO:0061045	negative regulation of wound healing

0.76	GO:0004866	endopeptidase inhibitor activity
0.39	GO:0008061	chitin binding
0.34	GO:0050431	transforming growth factor beta binding
0.33	GO:0003723	RNA binding

0.70	GO:0005615	extracellular space
0.33	GO:0031225	anchored component of membrane
0.33	GO:0005730	nucleolus
0.33	GO:0005654	nucleoplasm
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1FTB6|T1FTB6_HELRO
Uncharacterized protein
Search

0.76	GO:0010951	negative regulation of endopeptidase activity
0.43	GO:0072675	osteoclast fusion
0.43	GO:0061045	negative regulation of wound healing
0.43	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.43	GO:0010839	negative regulation of keratinocyte proliferation
0.42	GO:0045616	regulation of keratinocyte differentiation
0.40	GO:0050829	defense response to Gram-negative bacterium
0.40	GO:0001933	negative regulation of protein phosphorylation
0.38	GO:0001942	hair follicle development
0.32	GO:0006508	proteolysis

0.77	GO:0004866	endopeptidase inhibitor activity
0.44	GO:0050431	transforming growth factor beta binding
0.32	GO:0005509	calcium ion binding
0.32	GO:0008233	peptidase activity

0.73	GO:0005615	extracellular space
0.33	GO:0009986	cell surface
0.30	GO:0016020	membrane

0.32

GO:0008233

tr|T1FTB7|T1FTB7_HELRO
Uncharacterized protein
Search

0.76	GO:0010951	negative regulation of endopeptidase activity
0.39	GO:0050829	defense response to Gram-negative bacterium
0.38	GO:0061045	negative regulation of wound healing
0.38	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.38	GO:0006030	chitin metabolic process
0.37	GO:0072675	osteoclast fusion
0.37	GO:0010839	negative regulation of keratinocyte proliferation
0.37	GO:0045616	regulation of keratinocyte differentiation
0.36	GO:0001942	hair follicle development
0.35	GO:0001933	negative regulation of protein phosphorylation

0.76	GO:0004866	endopeptidase inhibitor activity
0.39	GO:0050431	transforming growth factor beta binding
0.38	GO:0008061	chitin binding
0.33	GO:0003723	RNA binding
0.32	GO:0008270	zinc ion binding
0.32	GO:0016887	ATPase activity
0.32	GO:0043168	anion binding
0.32	GO:0070279	vitamin B6 binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0050662	coenzyme binding

0.73	GO:0005615	extracellular space
0.34	GO:0031225	anchored component of membrane
0.33	GO:0005886	plasma membrane
0.33	GO:0098533	ATPase dependent transmembrane transport complex
0.33	GO:0098796	membrane protein complex
0.32	GO:0005634	nucleus

0.32

GO:0016887

tr|T1FTB8|T1FTB8_HELRO
Uncharacterized protein
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tr|T1FTB9|T1FTB9_HELRO
Metalloendopeptidase
Search

0.55	Metalloendopeptidase

0.61	GO:0006508	proteolysis
0.35	GO:0007275	multicellular organism development
0.35	GO:0022617	extracellular matrix disassembly
0.35	GO:0030154	cell differentiation
0.34	GO:0001503	ossification

0.70	GO:0004222	metalloendopeptidase activity
0.70	GO:0005509	calcium ion binding
0.63	GO:0008270	zinc ion binding
0.36	GO:0005518	collagen binding
0.35	GO:0003676	nucleic acid binding
0.34	GO:0016874	ligase activity
0.33	GO:0004252	serine-type endopeptidase activity

0.34	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.70

GO:0004222

tr|T1FTC0|T1FTC0_HELRO
Uncharacterized protein
Search

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.38	GO:0018095	protein polyglutamylation
0.37	GO:0006366	transcription by RNA polymerase II
0.36	GO:1902680	positive regulation of RNA biosynthetic process
0.36	GO:0007275	multicellular organism development

0.60	GO:0003700	DNA binding transcription factor activity
0.39	GO:0004835	tubulin-tyrosine ligase activity
0.37	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.36	GO:0003723	RNA binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.38	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.39

EC:6.3.2.25

GO:0004835

tr|T1FTC1|T1FTC1_HELRO
Uncharacterized protein
Search

0.60	39S ribosomal protein L49, mitochondrial

0.68	GO:0000398	mRNA splicing, via spliceosome
0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.53	GO:0009059	macromolecule biosynthetic process

0.64	GO:0003735	structural constituent of ribosome
0.36	GO:0008270	zinc ion binding

0.68	GO:0005681	spliceosomal complex
0.61	GO:0005840	ribosome

tr|T1FTC2|T1FTC2_HELRO
Uncharacterized protein
Search

0.64	GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter
0.59	GO:0006368	transcription elongation from RNA polymerase II promoter
0.56	GO:0045944	positive regulation of transcription by RNA polymerase II
0.48	GO:0006414	translational elongation

0.59	GO:0003723	RNA binding
0.36	GO:0005515	protein binding

0.86	GO:0032021	NELF complex
0.59	GO:0017053	transcriptional repressor complex
0.39	GO:0005694	chromosome

tr|T1FTC3|T1FTC3_HELRO
Uncharacterized protein
Search

0.79	GO:0007229	integrin-mediated signaling pathway
0.72	GO:0007155	cell adhesion
0.45	GO:0090245	axis elongation involved in somitogenesis
0.44	GO:0070121	Kupffer's vesicle development
0.44	GO:0001935	endothelial cell proliferation
0.43	GO:0042074	cell migration involved in gastrulation
0.42	GO:0001525	angiogenesis
0.39	GO:0033334	fin morphogenesis

0.42	GO:0050840	extracellular matrix binding
0.40	GO:0042802	identical protein binding
0.32	GO:0016740	transferase activity

0.81	GO:0008305	integrin complex
0.41	GO:0009897	external side of plasma membrane
0.41	GO:0005925	focal adhesion
0.41	GO:0070062	extracellular exosome

0.32

GO:0016740

tr|T1FTC4|T1FTC4_HELRO
Uncharacterized protein
Search

tr|T1FTC5|T1FTC5_HELRO
Uncharacterized protein
Search

tr|T1FTC6|T1FTC6_HELRO
Uncharacterized protein
Search

0.89	Mitochondrial ATPase inhibitor, IATP

0.81	GO:0032780	negative regulation of ATPase activity
0.40	GO:0006783	heme biosynthetic process
0.40	GO:0035999	tetrahydrofolate interconversion
0.40	GO:0009396	folic acid-containing compound biosynthetic process
0.40	GO:0043009	chordate embryonic development
0.35	GO:0050830	defense response to Gram-positive bacterium
0.35	GO:0030218	erythrocyte differentiation

0.82	GO:0042030	ATPase inhibitor activity
0.43	GO:0051117	ATPase binding
0.42	GO:0030272	5-formyltetrahydrofolate cyclo-ligase activity
0.32	GO:0003677	DNA binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0046872	metal ion binding

0.61	GO:0005739	mitochondrion
0.33	GO:0005634	nucleus

0.42	EC:6.3.3.2	GO:0030272
0.42	KEGG:R02301	GO:0030272

tr|T1FTC7|T1FTC7_HELRO
Uncharacterized protein
Search

ALDH4A1

0.37	Aldehyde dehydrogenase

0.79	GO:0010133	proline catabolic process to glutamate
0.53	GO:0055114	oxidation-reduction process
0.38	GO:0007005	mitochondrion organization
0.35	GO:0019470	4-hydroxyproline catabolic process
0.34	GO:0046487	glyoxylate metabolic process
0.34	GO:0006368	transcription elongation from RNA polymerase II promoter
0.33	GO:0016570	histone modification
0.33	GO:0006091	generation of precursor metabolites and energy

0.80	GO:0003842	1-pyrroline-5-carboxylate dehydrogenase activity
0.69	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.44	GO:0042802	identical protein binding
0.33	GO:0005198	structural molecule activity
0.33	GO:0009055	electron transfer activity

0.42	GO:0005739	mitochondrion
0.37	GO:0031974	membrane-enclosed lumen
0.36	GO:0044446	intracellular organelle part
0.35	GO:0045111	intermediate filament cytoskeleton
0.34	GO:0099512	supramolecular fiber
0.33	GO:0000428	DNA-directed RNA polymerase complex
0.33	GO:0005634	nucleus
0.32	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

0.80

EC:1.5.1.12

GO:0003842

tr|T1FTC8|T1FTC8_HELRO
Uncharacterized protein
Search

0.30

GO:0044425

membrane part

tr|T1FTC9|T1FTC9_HELRO
Uncharacterized protein
Search

tr|T1FTD0|T1FTD0_HELRO
Uncharacterized protein
Search

tr|T1FTD1|T1FTD1_HELRO
Uncharacterized protein
Search

tr|T1FTD2|T1FTD2_HELRO
Uncharacterized protein
Search

tr|T1FTD3|T1FTD3_HELRO
Uncharacterized protein
Search

0.44	GO:0007186	G-protein coupled receptor signaling pathway
0.39	GO:0006260	DNA replication
0.37	GO:1903506	regulation of nucleic acid-templated transcription
0.37	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.37	GO:0010468	regulation of gene expression

0.44	GO:0004930	G-protein coupled receptor activity
0.40	GO:0003697	single-stranded DNA binding
0.39	GO:0043565	sequence-specific DNA binding
0.39	GO:0046872	metal ion binding
0.38	GO:0003700	DNA binding transcription factor activity

0.38	GO:0005634	nucleus
0.30	GO:0044425	membrane part

tr|T1FTD4|T1FTD4_HELRO
Uncharacterized protein
Search

0.63

GO:0006468

protein phosphorylation

0.64	GO:0004672	protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

tr|T1FTD5|T1FTD5_HELRO
Uncharacterized protein
Search

tr|T1FTD6|T1FTD6_HELRO
Uncharacterized protein
Search

0.64	GO:0007015	actin filament organization
0.56	GO:0061462	protein localization to lysosome
0.56	GO:1904262	negative regulation of TORC1 signaling
0.55	GO:0034198	cellular response to amino acid starvation
0.55	GO:0042149	cellular response to glucose starvation
0.42	GO:0006413	translational initiation
0.38	GO:0035725	sodium ion transmembrane transport
0.38	GO:0006816	calcium ion transport
0.37	GO:0060289	compartment boundary maintenance
0.36	GO:0007455	eye-antennal disc morphogenesis

0.64	GO:0003779	actin binding
0.50	GO:0032403	protein complex binding
0.39	GO:0005432	calcium:sodium antiporter activity
0.38	GO:0051020	GTPase binding
0.38	GO:0003676	nucleic acid binding
0.36	GO:0046872	metal ion binding
0.36	GO:0016772	transferase activity, transferring phosphorus-containing groups
0.36	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.36	GO:0050825	ice binding
0.36	GO:0001104	RNA polymerase II transcription cofactor activity

0.64	GO:0015629	actin cytoskeleton
0.60	GO:0099571	postsynaptic cytoskeleton
0.58	GO:0140007	KICSTOR complex
0.54	GO:0030027	lamellipodium
0.49	GO:0099513	polymeric cytoskeletal fiber
0.44	GO:0043234	protein complex
0.36	GO:0032420	stereocilium
0.36	GO:0005634	nucleus
0.36	GO:0005765	lysosomal membrane
0.36	GO:0016035	zeta DNA polymerase complex

0.36

EC:2.7

GO:0016772

tr|T1FTD7|T1FTD7_HELRO
Uncharacterized protein
Search

0.39	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.38	GO:0016525	negative regulation of angiogenesis
0.37	GO:0007275	multicellular organism development
0.37	GO:0009653	anatomical structure morphogenesis
0.37	GO:0007492	endoderm development
0.36	GO:0071495	cellular response to endogenous stimulus
0.36	GO:0071559	response to transforming growth factor beta
0.36	GO:0071310	cellular response to organic substance
0.36	GO:0030198	extracellular matrix organization
0.36	GO:0008283	cell proliferation

0.66	GO:0005201	extracellular matrix structural constituent
0.40	GO:0042302	structural constituent of cuticle
0.37	GO:0005509	calcium ion binding
0.35	GO:0048407	platelet-derived growth factor binding
0.35	GO:0005178	integrin binding
0.34	GO:0030246	carbohydrate binding
0.34	GO:0008061	chitin binding
0.34	GO:0003677	DNA binding
0.34	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.63	GO:0005581	collagen trimer
0.48	GO:0005604	basement membrane
0.40	GO:0098645	collagen network
0.37	GO:0005829	cytosol
0.36	GO:0005615	extracellular space
0.34	GO:0005783	endoplasmic reticulum
0.30	GO:0016020	membrane

0.34

GO:0004553

tr|T1FTD8|T1FTD8_HELRO
Anoctamin
Search

0.36

Anoctamin

0.44	GO:1902476	chloride transmembrane transport
0.40	GO:0098655	cation transmembrane transport
0.34	GO:0006814	sodium ion transport

0.47	GO:0061778	intracellular chloride channel activity
0.45	GO:0005227	calcium activated cation channel activity
0.36	GO:0046983	protein dimerization activity
0.35	GO:0005272	sodium channel activity
0.34	GO:0017128	phospholipid scramblase activity

0.38	GO:0005886	plasma membrane
0.35	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

tr|T1FTD9|T1FTD9_HELRO
Uncharacterized protein
Search

0.83	GO:0071526	semaphorin-plexin signaling pathway
0.55	GO:0021935	cerebellar granule cell precursor tangential migration
0.53	GO:0060174	limb bud formation
0.52	GO:0060037	pharyngeal system development
0.52	GO:0051642	centrosome localization
0.51	GO:0001756	somitogenesis
0.51	GO:0051270	regulation of cellular component movement
0.50	GO:0040012	regulation of locomotion
0.50	GO:0021915	neural tube development
0.50	GO:0021785	branchiomotor neuron axon guidance

0.84	GO:0017154	semaphorin receptor activity
0.47	GO:0042802	identical protein binding

0.44	GO:0005887	integral component of plasma membrane
0.36	GO:0002116	semaphorin receptor complex
0.34	GO:0030054	cell junction
0.33	GO:0005634	nucleus

tr|T1FTE0|T1FTE0_HELRO
Uncharacterized protein
Search

0.38	Flagellar hook-length control protein FliK

0.47	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.45	GO:0007528	neuromuscular junction development
0.42	GO:0030198	extracellular matrix organization
0.42	GO:0007275	multicellular organism development
0.40	GO:0030154	cell differentiation
0.39	GO:0009653	anatomical structure morphogenesis
0.39	GO:0071230	cellular response to amino acid stimulus
0.37	GO:0016049	cell growth
0.37	GO:0048589	developmental growth
0.37	GO:0120036	plasma membrane bounded cell projection organization

0.68	GO:0005201	extracellular matrix structural constituent
0.39	GO:0042302	structural constituent of cuticle
0.36	GO:0048407	platelet-derived growth factor binding
0.35	GO:0004867	serine-type endopeptidase inhibitor activity
0.35	GO:0005509	calcium ion binding
0.34	GO:0008201	heparin binding
0.33	GO:0008061	chitin binding
0.33	GO:0051060	pullulanase activity
0.33	GO:0005044	scavenger receptor activity
0.32	GO:0030246	carbohydrate binding

0.68	GO:0005581	collagen trimer
0.64	GO:0005604	basement membrane
0.49	GO:0098645	collagen network
0.44	GO:0031594	neuromuscular junction
0.35	GO:0005615	extracellular space
0.34	GO:0005788	endoplasmic reticulum lumen
0.34	GO:0030054	cell junction
0.33	GO:0036338	viral membrane
0.32	GO:0071944	cell periphery
0.32	GO:0043232	intracellular non-membrane-bounded organelle

0.33

EC:3.2.1.41

GO:0051060

tr|T1FTE1|T1FTE1_HELRO
Uncharacterized protein
Search

tr|T1FTE2|T1FTE2_HELRO
Uncharacterized protein
Search

0.40	GO:0001937	negative regulation of endothelial cell proliferation
0.39	GO:0050900	leukocyte migration
0.38	GO:0006418	tRNA aminoacylation for protein translation
0.38	GO:0007267	cell-cell signaling
0.35	GO:1990564	protein polyufmylation
0.34	GO:0006954	inflammatory response
0.34	GO:0010469	regulation of receptor activity
0.32	GO:0006886	intracellular protein transport

0.63	GO:0000049	tRNA binding
0.41	GO:0016875	ligase activity, forming carbon-oxygen bonds
0.40	GO:0140101	catalytic activity, acting on a tRNA
0.38	GO:0042803	protein homodimerization activity
0.38	GO:0051020	GTPase binding
0.34	GO:0005125	cytokine activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.43	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex
0.40	GO:0017102	methionyl glutamyl tRNA synthetase complex
0.38	GO:0009986	cell surface
0.37	GO:0005783	endoplasmic reticulum
0.37	GO:0005829	cytosol
0.32	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.41

EC:6.1

GO:0016875

tr|T1FTE3|T1FTE3_HELRO
Uncharacterized protein
Search

tr|T1FTE4|T1FTE4_HELRO
Uroporphyrinogen decarboxylase
Search

0.49	Uroporphyrinogen decarboxylase

0.73	GO:0006782	protoporphyrinogen IX biosynthetic process
0.33	GO:0006412	translation

0.79	GO:0004853	uroporphyrinogen decarboxylase activity
0.33	GO:0003735	structural constituent of ribosome

0.39	GO:0005829	cytosol
0.36	GO:0005654	nucleoplasm
0.33	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.79

EC:4.1.1.37

GO:0004853

tr|T1FTE5|T1FTE5_HELRO
Uncharacterized protein
Search

0.89	Fibrinolytic enzyme, isozyme C

0.61	GO:0006508	proteolysis
0.42	GO:0016310	phosphorylation
0.39	GO:0042730	fibrinolysis
0.39	GO:0007596	blood coagulation
0.38	GO:0001867	complement activation, lectin pathway

0.69	GO:0004252	serine-type endopeptidase activity
0.43	GO:0016301	kinase activity
0.37	GO:0005509	calcium ion binding
0.36	GO:0001855	complement component C4b binding
0.35	GO:0048306	calcium-dependent protein binding

0.38	GO:0046658	anchored component of plasma membrane
0.37	GO:0019897	extrinsic component of plasma membrane
0.35	GO:0005576	extracellular region
0.35	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.69

GO:0004252

tr|T1FTE6|T1FTE6_HELRO
Uncharacterized protein
Search

tr|T1FTE7|T1FTE7_HELRO
Uncharacterized protein
Search

tr|T1FTE8|T1FTE8_HELRO
Lipase maturation factor
Search

0.43	Lipase maturation factor

0.72	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1FTE9|T1FTE9_HELRO
Uncharacterized protein
Search

0.40	GO:0034470	ncRNA processing
0.40	GO:0006904	vesicle docking involved in exocytosis
0.40	GO:0043412	macromolecule modification
0.40	GO:0016072	rRNA metabolic process
0.39	GO:0042254	ribosome biogenesis
0.39	GO:0045454	cell redox homeostasis
0.38	GO:0006508	proteolysis
0.37	GO:0043632	modification-dependent macromolecule catabolic process
0.37	GO:0044257	cellular protein catabolic process
0.36	GO:0006399	tRNA metabolic process

0.41	GO:0043531	ADP binding
0.41	GO:0008270	zinc ion binding
0.40	GO:0003676	nucleic acid binding
0.39	GO:0009982	pseudouridine synthase activity
0.38	GO:0140096	catalytic activity, acting on a protein
0.37	GO:0043021	ribonucleoprotein complex binding
0.37	GO:0016763	transferase activity, transferring pentosyl groups
0.37	GO:0032550	purine ribonucleoside binding
0.37	GO:0019001	guanyl nucleotide binding
0.36	GO:0016787	hydrolase activity

0.43	GO:0005634	nucleus
0.42	GO:0030684	preribosome
0.36	GO:0031974	membrane-enclosed lumen
0.35	GO:0043232	intracellular non-membrane-bounded organelle
0.35	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.39

EC:5.4.99.12

GO:0009982

tr|T1FTF0|T1FTF0_HELRO
Uncharacterized protein
Search

tr|T1FTF1|T1FTF1_HELRO
Uncharacterized protein
Search

0.52	GO:0032259	methylation
0.35	GO:0006869	lipid transport
0.34	GO:0071805	potassium ion transmembrane transport

0.52	GO:0008168	methyltransferase activity
0.36	GO:0005319	lipid transporter activity
0.35	GO:0016286	small conductance calcium-activated potassium channel activity

0.30

GO:0016021

integral component of membrane

0.52

GO:0008168

tr|T1FTF2|T1FTF2_HELRO
Uncharacterized protein
Search

tr|T1FTF3|T1FTF3_HELRO
Uncharacterized protein
Search

0.57	Cytosolic carboxypeptidase-like protein 5

0.61	GO:0006508	proteolysis
0.58	GO:0035608	protein deglutamylation
0.36	GO:0051607	defense response to virus

0.77	GO:0004181	metallocarboxypeptidase activity
0.63	GO:0008270	zinc ion binding
0.36	GO:0015631	tubulin binding

0.40	GO:0045171	intercellular bridge
0.40	GO:0030496	midbody
0.40	GO:0072686	mitotic spindle
0.37	GO:0005829	cytosol
0.36	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.77

EC:3.4.17

GO:0004181

tr|T1FTF4|T1FTF4_HELRO
Uncharacterized protein
Search

0.44	GO:0006629	lipid metabolic process
0.43	GO:1900402	regulation of carbohydrate metabolic process by regulation of transcription from RNA polymerase II promoter
0.36	GO:0016310	phosphorylation
0.36	GO:0006284	base-excision repair
0.36	GO:0016567	protein ubiquitination
0.34	GO:0035556	intracellular signal transduction
0.34	GO:0019637	organophosphate metabolic process
0.33	GO:0055114	oxidation-reduction process

0.60	GO:0046983	protein dimerization activity
0.47	GO:0008081	phosphoric diester hydrolase activity
0.40	GO:0000989	transcription factor activity, transcription factor binding
0.38	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity
0.38	GO:0005543	phospholipid binding
0.36	GO:0004842	ubiquitin-protein transferase activity
0.35	GO:0010181	FMN binding
0.35	GO:0003779	actin binding
0.35	GO:0016874	ligase activity
0.34	GO:0003723	RNA binding

0.41	GO:0020011	apicoplast
0.30	GO:0016020	membrane

0.47	EC:3.1.4	GO:0008081
0.38	KEGG:R03469	GO:0016308

tr|T1FTF5|T1FTF5_HELRO
Uncharacterized protein
Search

AURKA

0.59	Aurora kinase A-B

0.67	GO:0007049	cell cycle
0.63	GO:0006468	protein phosphorylation
0.60	GO:0031023	microtubule organizing center organization
0.60	GO:0000280	nuclear division
0.59	GO:0018209	peptidyl-serine modification
0.55	GO:1900195	positive regulation of oocyte maturation
0.55	GO:0016570	histone modification
0.55	GO:0022414	reproductive process
0.54	GO:0032091	negative regulation of protein binding
0.53	GO:0097421	liver regeneration

0.69	GO:0004674	protein serine/threonine kinase activity
0.59	GO:0035173	histone kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.51	GO:0019900	kinase binding
0.48	GO:0031625	ubiquitin protein ligase binding
0.47	GO:0046982	protein heterodimerization activity
0.45	GO:0004712	protein serine/threonine/tyrosine kinase activity

0.57	GO:0032133	chromosome passenger complex
0.56	GO:0031616	spindle pole centrosome
0.54	GO:0005876	spindle microtubule
0.54	GO:0042585	germinal vesicle
0.53	GO:0072687	meiotic spindle
0.53	GO:0072686	mitotic spindle
0.53	GO:0043203	axon hillock
0.52	GO:0045120	pronucleus
0.51	GO:0051233	spindle midzone
0.50	GO:0000780	condensed nuclear chromosome, centromeric region

0.69

GO:0004674

tr|T1FTF6|T1FTF6_HELRO
Uncharacterized protein
Search

0.78	GO:0030522	intracellular receptor signaling pathway
0.78	GO:0043401	steroid hormone mediated signaling pathway
0.78	GO:0001578	microtubule bundle formation
0.68	GO:0000910	cytokinesis
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression
0.36	GO:0016042	lipid catabolic process

0.84	GO:0004887	thyroid hormone receptor activity
0.79	GO:0003707	steroid hormone receptor activity
0.70	GO:0008017	microtubule binding
0.54	GO:0003677	DNA binding
0.44	GO:0008270	zinc ion binding
0.37	GO:0004806	triglyceride lipase activity

0.65	GO:0005856	cytoskeleton
0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.37

EC:3.1.1.3

GO:0004806

tr|T1FTF7|T1FTF7_HELRO
Uncharacterized protein
Search

tr|T1FTF8|T1FTF8_HELRO
Uncharacterized protein
Search

MDH

0.40	L-sulfolactate dehydrogenase

0.53	GO:0055114	oxidation-reduction process
0.34	GO:0006457	protein folding

0.54	GO:0016491	oxidoreductase activity
0.34	GO:0051082	unfolded protein binding

0.30

GO:0044425

membrane part

0.54

GO:0016491

tr|T1FTF9|T1FTF9_HELRO
Uncharacterized protein
Search

tr|T1FTG0|T1FTG0_HELRO
Uncharacterized protein
Search

0.57	GO:0090481	pyrimidine nucleotide-sugar transmembrane transport
0.52	GO:0030206	chondroitin sulfate biosynthetic process
0.49	GO:0009792	embryo development ending in birth or egg hatching
0.48	GO:0001501	skeletal system development
0.44	GO:0008643	carbohydrate transport
0.41	GO:1903354	regulation of distal tip cell migration
0.40	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process
0.40	GO:0006744	ubiquinone biosynthetic process
0.40	GO:0035262	gonad morphogenesis
0.40	GO:0040025	vulval development

0.57	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity
0.34	GO:0004814	arginine-tRNA ligase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.44	GO:0005783	endoplasmic reticulum
0.40	GO:0031314	extrinsic component of mitochondrial inner membrane
0.37	GO:0031984	organelle subcompartment
0.37	GO:0005794	Golgi apparatus
0.36	GO:0098588	bounding membrane of organelle
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.30	GO:0016021	integral component of membrane

0.34

EC:6.1.1.19

GO:0004814

tr|T1FTG1|T1FTG1_HELRO
Uncharacterized protein
Search

tr|T1FTG2|T1FTG2_HELRO
Uncharacterized protein
Search

0.85	GO:0042051	compound eye photoreceptor development
0.48	GO:0010629	negative regulation of gene expression
0.41	GO:0032259	methylation

0.56	GO:0042826	histone deacetylase binding
0.41	GO:0008168	methyltransferase activity

0.48

GO:0005737

cytoplasm

0.41

GO:0008168

tr|T1FTG3|T1FTG3_HELRO
Uncharacterized protein
Search

DHX15

0.58	Mrna splicing factor atp dependent rna helicase

0.45	GO:1900745	positive regulation of p38MAPK cascade
0.44	GO:0000398	mRNA splicing, via spliceosome
0.39	GO:0043279	response to alkaloid
0.36	GO:0009636	response to toxic substance

0.67	GO:0004386	helicase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0003725	double-stranded RNA binding
0.45	GO:0008186	RNA-dependent ATPase activity
0.40	GO:0140098	catalytic activity, acting on RNA
0.34	GO:0005515	protein binding
0.33	GO:0016779	nucleotidyltransferase activity

0.54	GO:0071008	U2-type post-mRNA release spliceosomal complex
0.54	GO:0005689	U12-type spliceosomal complex
0.52	GO:0016607	nuclear speck
0.36	GO:0005737	cytoplasm
0.36	GO:0005730	nucleolus
0.34	GO:0071011	precatalytic spliceosome
0.34	GO:0071013	catalytic step 2 spliceosome
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:2.7.7

GO:0016779

tr|T1FTG4|T1FTG4_HELRO
Uncharacterized protein
Search

0.53	GO:0055114	oxidation-reduction process
0.46	GO:0046208	spermine catabolic process
0.44	GO:1901304	regulation of spermidine biosynthetic process
0.44	GO:0046203	spermidine catabolic process
0.43	GO:0033240	positive regulation of cellular amine metabolic process
0.42	GO:0009447	putrescine catabolic process
0.41	GO:0009446	putrescine biosynthetic process
0.40	GO:0030097	hemopoiesis
0.39	GO:0031328	positive regulation of cellular biosynthetic process
0.34	GO:0006511	ubiquitin-dependent protein catabolic process

0.54	GO:0016491	oxidoreductase activity
0.39	GO:0005102	receptor binding
0.34	GO:0031625	ubiquitin protein ligase binding
0.32	GO:0051537	2 iron, 2 sulfur cluster binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.31	GO:0003676	nucleic acid binding

0.37	GO:0031965	nuclear membrane
0.36	GO:0005654	nucleoplasm

0.54

GO:0016491

tr|T1FTG5|T1FTG5_HELRO
Uncharacterized protein
Search

tr|T1FTG6|T1FTG6_HELRO
Uncharacterized protein
Search

0.63

GO:0006468

protein phosphorylation

0.64	GO:0004672	protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

tr|T1FTG7|T1FTG7_HELRO
Uncharacterized protein
Search

0.52	GO:0007018	microtubule-based movement
0.48	GO:0051568	histone H3-K4 methylation
0.47	GO:0015031	protein transport
0.42	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway
0.41	GO:0043627	response to estrogen
0.40	GO:0060255	regulation of macromolecule metabolic process
0.39	GO:0008284	positive regulation of cell proliferation
0.39	GO:0031323	regulation of cellular metabolic process
0.39	GO:0051171	regulation of nitrogen compound metabolic process
0.39	GO:0080090	regulation of primary metabolic process

0.58	GO:0019894	kinesin binding
0.48	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.39	GO:0044212	transcription regulatory region DNA binding
0.38	GO:0046872	metal ion binding
0.37	GO:0005078	MAP-kinase scaffold activity
0.37	GO:0008140	cAMP response element binding protein binding
0.36	GO:0003700	DNA binding transcription factor activity
0.36	GO:0043168	anion binding
0.36	GO:0017076	purine nucleotide binding
0.36	GO:0097367	carbohydrate derivative binding

0.53	GO:0030176	integral component of endoplasmic reticulum membrane
0.46	GO:0035097	histone methyltransferase complex
0.36	GO:0008540	proteasome regulatory particle, base subcomplex
0.35	GO:0005779	integral component of peroxisomal membrane
0.33	GO:0005840	ribosome

0.35

EC:2.1.3

GO:0016743

tr|T1FTG8|T1FTG8_HELRO
Uncharacterized protein
Search

0.67	GO:0030866	cortical actin cytoskeleton organization
0.54	GO:1904778	positive regulation of protein localization to cell cortex
0.44	GO:0031032	actomyosin structure organization
0.41	GO:0007016	cytoskeletal anchoring at plasma membrane
0.40	GO:0001558	regulation of cell growth
0.34	GO:0051301	cell division
0.34	GO:0007049	cell cycle
0.33	GO:0008360	regulation of cell shape
0.33	GO:0098655	cation transmembrane transport

0.70	GO:0008092	cytoskeletal protein binding
0.59	GO:0005198	structural molecule activity
0.53	GO:0042731	PH domain binding
0.34	GO:0046982	protein heterodimerization activity
0.34	GO:0005261	cation channel activity

0.69	GO:0005856	cytoskeleton
0.51	GO:0099738	cell cortex region
0.50	GO:0030054	cell junction
0.50	GO:0008180	COP9 signalosome
0.45	GO:0005654	nucleoplasm
0.42	GO:0005886	plasma membrane
0.39	GO:0070062	extracellular exosome
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|T1FTG9|T1FTG9_HELRO
Uncharacterized protein
Search

0.49	GO:0006429	leucyl-tRNA aminoacylation
0.47	GO:0106074	aminoacyl-tRNA metabolism involved in translational fidelity
0.43	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA
0.41	GO:0043085	positive regulation of catalytic activity
0.40	GO:0036211	protein modification process
0.39	GO:0048015	phosphatidylinositol-mediated signaling
0.39	GO:0006950	response to stress
0.39	GO:0000256	allantoin catabolic process
0.38	GO:0046854	phosphatidylinositol phosphorylation
0.38	GO:0000278	mitotic cell cycle

0.49	GO:0004823	leucine-tRNA ligase activity
0.47	GO:0002161	aminoacyl-tRNA editing activity
0.42	GO:0030554	adenyl nucleotide binding
0.42	GO:0097367	carbohydrate derivative binding
0.42	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0008144	drug binding
0.41	GO:0008047	enzyme activator activity
0.39	GO:0004037	allantoicase activity
0.39	GO:0004722	protein serine/threonine phosphatase activity
0.39	GO:0046872	metal ion binding

0.41	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm
0.37	GO:0061695	transferase complex, transferring phosphorus-containing groups
0.36	GO:0005578	proteinaceous extracellular matrix
0.35	GO:0044446	intracellular organelle part
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.49	EC:6.1.1.4	GO:0004823
0.49	KEGG:R03657	GO:0004823

tr|T1FTH0|T1FTH0_HELRO
Uncharacterized protein
Search

0.49	GO:0016570	histone modification
0.47	GO:0006368	transcription elongation from RNA polymerase II promoter
0.42	GO:0000413	protein peptidyl-prolyl isomerization
0.42	GO:0016579	protein deubiquitination
0.41	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process
0.41	GO:0042254	ribosome biogenesis
0.41	GO:0006511	ubiquitin-dependent protein catabolic process
0.38	GO:0006357	regulation of transcription by RNA polymerase II
0.38	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.38	GO:0016311	dephosphorylation

0.47	GO:0046982	protein heterodimerization activity
0.45	GO:0005528	FK506 binding
0.42	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.42	GO:1990269	RNA polymerase II C-terminal domain phosphoserine binding
0.42	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.41	GO:0003677	DNA binding
0.41	GO:0016788	hydrolase activity, acting on ester bonds
0.40	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.39	GO:0140098	catalytic activity, acting on RNA
0.38	GO:0003887	DNA-directed DNA polymerase activity

0.48	GO:0005634	nucleus
0.46	GO:0043233	organelle lumen
0.45	GO:0000428	DNA-directed RNA polymerase complex
0.42	GO:0044446	intracellular organelle part
0.40	GO:0043234	protein complex
0.38	GO:0043232	intracellular non-membrane-bounded organelle
0.37	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.42

EC:5.2.1.8

GO:0003755

tr|T1FTH1|T1FTH1_HELRO
Uncharacterized protein
Search

0.10	Myosin light chain kinase, smooth muscle (Fragment)

0.57	GO:0006468	protein phosphorylation
0.52	GO:0060414	aorta smooth muscle tissue morphogenesis
0.51	GO:0032060	bleb assembly
0.50	GO:0071476	cellular hypotonic response
0.49	GO:0090303	positive regulation of wound healing
0.49	GO:2000145	regulation of cell motility
0.49	GO:0051928	positive regulation of calcium ion transport
0.48	GO:0051272	positive regulation of cellular component movement
0.48	GO:0040017	positive regulation of locomotion
0.42	GO:0006939	smooth muscle contraction

0.58	GO:0004672	protein kinase activity
0.50	GO:0032559	adenyl ribonucleotide binding
0.50	GO:0008144	drug binding
0.50	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0005516	calmodulin binding
0.38	GO:0003779	actin binding
0.36	GO:0019899	enzyme binding
0.35	GO:0046872	metal ion binding

0.50	GO:0032154	cleavage furrow
0.49	GO:0030027	lamellipodium
0.49	GO:0097517	contractile actin filament bundle
0.49	GO:0042641	actomyosin
0.39	GO:0005886	plasma membrane
0.37	GO:0005737	cytoplasm
0.37	GO:0070062	extracellular exosome
0.36	GO:0005911	cell-cell junction

tr|T1FTH2|T1FTH2_HELRO
Uncharacterized protein
Search

tr|T1FTH3|T1FTH3_HELRO
Uncharacterized protein
Search

tr|T1FTH4|T1FTH4_HELRO
Uncharacterized protein
Search

0.83	GO:0030178	negative regulation of Wnt signaling pathway
0.74	GO:0016055	Wnt signaling pathway
0.42	GO:0060828	regulation of canonical Wnt signaling pathway
0.39	GO:1905126	regulation of axo-dendritic protein transport
0.39	GO:0046673	negative regulation of compound eye retinal cell programmed cell death
0.39	GO:0030720	oocyte localization involved in germarium-derived egg chamber formation
0.39	GO:0035293	chitin-based larval cuticle pattern formation
0.38	GO:0007367	segment polarity determination
0.38	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity
0.38	GO:0007447	imaginal disc pattern formation

0.84	GO:0008013	beta-catenin binding
0.43	GO:0016757	transferase activity, transferring glycosyl groups
0.39	GO:0008017	microtubule binding
0.32	GO:0003676	nucleic acid binding

0.38	GO:0030877	beta-catenin destruction complex
0.37	GO:0045177	apical part of cell
0.37	GO:0030424	axon
0.34	GO:0005634	nucleus

0.43

GO:0016757

tr|T1FTH5|T1FTH5_HELRO
Uncharacterized protein
Search

tr|T1FTH6|T1FTH6_HELRO
Uncharacterized protein
Search

COG4

0.56	Component of oligomeric golgi complex 4

0.86	GO:0048213	Golgi vesicle prefusion complex stabilization
0.84	GO:0000301	retrograde transport, vesicle recycling within Golgi
0.79	GO:0007030	Golgi organization
0.78	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.43	GO:0015031	protein transport
0.39	GO:0006888	ER to Golgi vesicle-mediated transport

0.44

GO:0042802

identical protein binding

0.78	GO:0017119	Golgi transport complex
0.46	GO:0000139	Golgi membrane
0.43	GO:0005783	endoplasmic reticulum
0.39	GO:0005802	trans-Golgi network

tr|T1FTH7|T1FTH7_HELRO
Uncharacterized protein
Search

0.52	GO:1901076	positive regulation of engulfment of apoptotic cell
0.42	GO:0040011	locomotion

0.53	GO:0030314	junctional membrane complex
0.30	GO:0044425	membrane part

tr|T1FTH8|T1FTH8_HELRO
Uncharacterized protein
Search

0.57	GO:0035562	negative regulation of chromatin binding
0.37	GO:0042790	nucleolar large rRNA transcription by RNA polymerase I
0.37	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly
0.36	GO:0045892	negative regulation of transcription, DNA-templated
0.35	GO:0006364	rRNA processing
0.32	GO:0050909	sensory perception of taste

0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0017025	TBP-class protein binding
0.35	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.34	GO:0017111	nucleoside-triphosphatase activity
0.34	GO:0003677	DNA binding
0.33	GO:0003700	DNA binding transcription factor activity

0.48	GO:0005654	nucleoplasm
0.35	GO:0000228	nuclear chromosome
0.30	GO:0031224	intrinsic component of membrane

0.35

GO:0003950

tr|T1FTH9|T1FTH9_HELRO
Uncharacterized protein
Search

0.33

GO:0006400

tRNA modification

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0004386	helicase activity
0.34	GO:0016763	transferase activity, transferring pentosyl groups

0.30

GO:0031224

intrinsic component of membrane

0.34

EC:2.4.2

GO:0016763

tr|T1FTI0|T1FTI0_HELRO
Gamma-tubulin complex component
Search

0.32	Gamma-tubulin complex component

0.79	GO:0007020	microtubule nucleation
0.46	GO:0090307	mitotic spindle assembly
0.46	GO:0051298	centrosome duplication
0.46	GO:0031122	cytoplasmic microtubule organization
0.44	GO:0051321	meiotic cell cycle

0.79	GO:0043015	gamma-tubulin binding
0.48	GO:0008017	microtubule binding
0.44	GO:0005200	structural constituent of cytoskeleton

0.77	GO:0000922	spindle pole
0.73	GO:0005815	microtubule organizing center
0.71	GO:0005874	microtubule
0.48	GO:0005737	cytoplasm
0.45	GO:0032155	cell division site part
0.42	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

tr|T1FTI1|T1FTI1_HELRO
Uncharacterized protein
Search

0.58

GO:0051301

cell division

0.30

GO:0044425

membrane part

tr|T1FTI2|T1FTI2_HELRO
Uncharacterized protein
Search

0.73	Transmembrane BAX inhibitor motif-containing protein 1

0.41	GO:1901215	negative regulation of neuron death
0.40	GO:0043066	negative regulation of apoptotic process
0.33	GO:0009607	response to biotic stimulus

0.30

GO:0044425

membrane part

tr|T1FTI3|T1FTI3_HELRO
Uncharacterized protein
Search

tr|T1FTI4|T1FTI4_HELRO
Uncharacterized protein
Search

0.58	GO:0006468	protein phosphorylation
0.52	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.49	GO:0031639	plasminogen activation
0.48	GO:0030538	embryonic genitalia morphogenesis
0.48	GO:0007223	Wnt signaling pathway, calcium modulating pathway
0.47	GO:0001502	cartilage condensation
0.46	GO:0060071	Wnt signaling pathway, planar cell polarity pathway
0.46	GO:0060395	SMAD protein signal transduction
0.46	GO:0042733	embryonic digit morphogenesis
0.46	GO:0001756	somitogenesis

0.59	GO:0004672	protein kinase activity
0.51	GO:0030554	adenyl nucleotide binding
0.50	GO:0097367	carbohydrate derivative binding
0.50	GO:0008144	drug binding
0.50	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0004252	serine-type endopeptidase activity
0.46	GO:0005109	frizzled binding
0.46	GO:0017147	Wnt-protein binding
0.44	GO:0005044	scavenger receptor activity
0.39	GO:0004888	transmembrane signaling receptor activity

0.43	GO:0005576	extracellular region
0.36	GO:0009986	cell surface
0.35	GO:0005622	intracellular
0.34	GO:0031982	vesicle
0.34	GO:0043025	neuronal cell body
0.34	GO:0030425	dendrite
0.34	GO:0019897	extrinsic component of plasma membrane
0.34	GO:0009898	cytoplasmic side of plasma membrane
0.33	GO:0000935	division septum
0.33	GO:0051286	cell tip

0.48	EC:3.4.21	GO:0004252
0.37	KEGG:R03876	GO:0004842

tr|T1FTI5|T1FTI5_HELRO
Uncharacterized protein
Search

ABCG2

0.83	ATP binding cassette subfamily G member 2 (Junior blood group)

0.50	GO:0055085	transmembrane transport
0.49	GO:0046415	urate metabolic process
0.48	GO:0033344	cholesterol efflux
0.43	GO:0015893	drug transport
0.37	GO:0097744	urate salt excretion
0.37	GO:1904612	response to 2,3,7,8-tetrachlorodibenzodioxine
0.37	GO:0019389	glucuronoside metabolic process
0.36	GO:1904479	negative regulation of intestinal absorption
0.36	GO:0060136	embryonic process involved in female pregnancy
0.36	GO:0051593	response to folic acid

0.61	GO:0016887	ATPase activity
0.58	GO:0015399	primary active transmembrane transporter activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0017127	cholesterol transporter activity
0.45	GO:0042803	protein homodimerization activity
0.36	GO:0042910	xenobiotic transmembrane transporter activity
0.36	GO:0015238	drug transmembrane transporter activity
0.35	GO:0005509	calcium ion binding

0.46	GO:0016324	apical plasma membrane
0.45	GO:0043235	receptor complex
0.41	GO:0005634	nucleus
0.36	GO:0031966	mitochondrial membrane
0.35	GO:0043190	ATP-binding cassette (ABC) transporter complex

0.61

GO:0016887

tr|T1FTI6|T1FTI6_HELRO
Uncharacterized protein
Search

tr|T1FTI7|T1FTI7_HELRO
Uncharacterized protein
Search

tr|T1FTI8|T1FTI8_HELRO
Uncharacterized protein
Search

tr|T1FTI9|T1FTI9_HELRO
Uncharacterized protein
Search

tr|T1FTJ0|T1FTJ0_HELRO
Uncharacterized protein
Search

0.77	Tgc transglutaminase/protease like domain containing protein involved in cytokinesis

0.39	GO:0006508	proteolysis
0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression

0.53	GO:0046872	metal ion binding
0.40	GO:0008233	peptidase activity
0.33	GO:0005515	protein binding

0.44	GO:0097610	cell surface furrow
0.43	GO:0032155	cell division site part
0.42	GO:0005938	cell cortex
0.35	GO:0005911	cell-cell junction
0.30	GO:0031224	intrinsic component of membrane

0.40

GO:0008233

tr|T1FTJ1|T1FTJ1_HELRO
Uncharacterized protein
Search

0.53	GO:0051568	histone H3-K4 methylation
0.46	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway
0.45	GO:0043627	response to estrogen
0.43	GO:0008284	positive regulation of cell proliferation
0.43	GO:0045944	positive regulation of transcription by RNA polymerase II
0.43	GO:0048268	clathrin coat assembly
0.39	GO:0006351	transcription, DNA-templated
0.39	GO:0006413	translational initiation
0.37	GO:0010216	maintenance of DNA methylation
0.37	GO:0090308	regulation of methylation-dependent chromatin silencing

0.53	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.45	GO:0044212	transcription regulatory region DNA binding
0.44	GO:0046982	protein heterodimerization activity
0.43	GO:0005545	1-phosphatidylinositol binding
0.43	GO:0046872	metal ion binding
0.42	GO:0030276	clathrin binding
0.40	GO:0140110	transcription regulator activity
0.39	GO:1990837	sequence-specific double-stranded DNA binding
0.39	GO:0003743	translation initiation factor activity
0.38	GO:0050825	ice binding

0.51	GO:0035097	histone methyltransferase complex
0.42	GO:0030136	clathrin-coated vesicle
0.42	GO:0000124	SAGA complex
0.41	GO:0046695	SLIK (SAGA-like) complex
0.40	GO:0005669	transcription factor TFIID complex
0.36	GO:0005720	nuclear heterochromatin
0.36	GO:0030173	integral component of Golgi membrane
0.36	GO:0005856	cytoskeleton
0.36	GO:0043198	dendritic shaft
0.36	GO:0030014	CCR4-NOT complex

0.35

GO:0016773

tr|T1FTJ2|T1FTJ2_HELRO
Uncharacterized protein
Search

SCARB2

0.74	Scavenger receptor class B member 2

0.68	GO:1905123	regulation of glucosylceramidase activity
0.66	GO:0006622	protein targeting to lysosome
0.62	GO:0001508	action potential
0.37	GO:0010976	positive regulation of neuron projection development

0.58	GO:0004872	receptor activity
0.55	GO:0019899	enzyme binding

0.69	GO:0005764	lysosome
0.64	GO:0005775	vacuolar lumen
0.59	GO:0098852	lytic vacuole membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1FTJ3|T1FTJ3_HELRO
Uncharacterized protein
Search

tr|T1FTJ4|T1FTJ4_HELRO
Uncharacterized protein
Search

tr|T1FTJ5|T1FTJ5_HELRO
Uncharacterized protein
Search

0.54	GO:0006397	mRNA processing
0.46	GO:0016998	cell wall macromolecule catabolic process
0.45	GO:0009253	peptidoglycan catabolic process
0.38	GO:0097435	supramolecular fiber organization
0.38	GO:0007010	cytoskeleton organization
0.38	GO:0007009	plasma membrane organization
0.37	GO:0097428	protein maturation by iron-sulfur cluster transfer
0.37	GO:0030029	actin filament-based process
0.37	GO:0032502	developmental process
0.36	GO:0043933	macromolecular complex subunit organization

0.49	GO:0045735	nutrient reservoir activity
0.48	GO:0003723	RNA binding
0.46	GO:0003796	lysozyme activity
0.40	GO:0008092	cytoskeletal protein binding
0.37	GO:0000989	transcription factor activity, transcription factor binding
0.37	GO:0047849	dextransucrase activity
0.37	GO:0019899	enzyme binding
0.36	GO:0005509	calcium ion binding
0.36	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.36	GO:0004672	protein kinase activity

0.50	GO:0005634	nucleus
0.41	GO:0005737	cytoplasm
0.36	GO:0070701	mucus layer
0.36	GO:0035371	microtubule plus-end
0.35	GO:0000922	spindle pole
0.35	GO:0000776	kinetochore
0.35	GO:0005912	adherens junction
0.35	GO:0005813	centrosome
0.35	GO:0017053	transcriptional repressor complex
0.35	GO:0015629	actin cytoskeleton

0.46

EC:3.2.1.17

GO:0003796

tr|T1FTJ6|T1FTJ6_HELRO
Uncharacterized protein
Search

tr|T1FTJ7|T1FTJ7_HELRO
Uncharacterized protein
Search

0.57	GO:0030154	cell differentiation
0.41	GO:0031507	heterochromatin assembly
0.39	GO:0006342	chromatin silencing
0.37	GO:0019226	transmission of nerve impulse
0.36	GO:0042552	myelination
0.36	GO:0007422	peripheral nervous system development
0.36	GO:0009653	anatomical structure morphogenesis
0.36	GO:0050808	synapse organization
0.35	GO:0120036	plasma membrane bounded cell projection organization
0.35	GO:0006935	chemotaxis

0.74	GO:0003682	chromatin binding
0.38	GO:0000976	transcription regulatory region sequence-specific DNA binding
0.34	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.33	GO:0005112	Notch binding
0.33	GO:0005509	calcium ion binding
0.32	GO:0030246	carbohydrate binding
0.32	GO:0008233	peptidase activity

0.41	GO:0005677	chromatin silencing complex
0.38	GO:0000785	chromatin
0.35	GO:0044421	extracellular region part
0.33	GO:0009986	cell surface
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0004553

tr|T1FTJ8|T1FTJ8_HELRO
Uncharacterized protein
Search

0.72	Mitochondrial inner membrane protease ATP23

0.61	GO:0006508	proteolysis
0.40	GO:0033615	mitochondrial proton-transporting ATP synthase complex assembly
0.40	GO:0007018	microtubule-based movement
0.38	GO:0051604	protein maturation
0.35	GO:0044267	cellular protein metabolic process
0.35	GO:0032781	positive regulation of ATPase activity
0.34	GO:0051259	protein oligomerization
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:0009059	macromolecule biosynthetic process

0.70	GO:0004222	metalloendopeptidase activity
0.53	GO:0046872	metal ion binding
0.40	GO:0003777	microtubule motor activity
0.36	GO:0032555	purine ribonucleotide binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0030554	adenyl nucleotide binding
0.36	GO:0008144	drug binding
0.35	GO:0016887	ATPase activity
0.35	GO:0001671	ATPase activator activity
0.34	GO:0051087	chaperone binding

0.41	GO:0030286	dynein complex
0.39	GO:0031314	extrinsic component of mitochondrial inner membrane
0.39	GO:0005758	mitochondrial intermembrane space
0.32	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

0.70

GO:0004222

tr|T1FTJ9|T1FTJ9_HELRO
Uncharacterized protein
Search

0.60	GO:0038007	netrin-activated signaling pathway
0.46	GO:0006956	complement activation
0.40	GO:0006508	proteolysis
0.37	GO:0032502	developmental process
0.37	GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
0.37	GO:0048015	phosphatidylinositol-mediated signaling
0.37	GO:0032501	multicellular organismal process
0.36	GO:0046854	phosphatidylinositol phosphorylation
0.36	GO:0007229	integrin-mediated signaling pathway
0.36	GO:0051171	regulation of nitrogen compound metabolic process

0.61	GO:0005042	netrin receptor activity
0.42	GO:0004222	metalloendopeptidase activity
0.38	GO:0046872	metal ion binding
0.38	GO:0003676	nucleic acid binding
0.35	GO:0008047	enzyme activator activity
0.35	GO:0000175	3'-5'-exoribonuclease activity
0.35	GO:0000829	inositol heptakisphosphate kinase activity
0.35	GO:0008234	cysteine-type peptidase activity
0.35	GO:0003700	DNA binding transcription factor activity
0.35	GO:0035091	phosphatidylinositol binding

0.47	GO:0005579	membrane attack complex
0.40	GO:0005576	extracellular region
0.37	GO:0005634	nucleus
0.35	GO:0030015	CCR4-NOT core complex
0.35	GO:0000932	P-body
0.35	GO:0020011	apicoplast
0.33	GO:0030686	90S preribosome
0.33	GO:0032040	small-subunit processome
0.33	GO:0031931	TORC1 complex
0.33	GO:0031982	vesicle

0.42

GO:0004222

tr|T1FTK0|T1FTK0_HELRO
Uncharacterized protein
Search

tr|T1FTK1|T1FTK1_HELRO
Uncharacterized protein
Search

tr|T1FTK2|T1FTK2_HELRO
Uncharacterized protein
Search

0.47	GO:0030198	extracellular matrix organization
0.46	GO:0010952	positive regulation of peptidase activity
0.45	GO:0007155	cell adhesion
0.37	GO:1901492	positive regulation of lymphangiogenesis
0.37	GO:0060837	blood vessel endothelial cell differentiation
0.36	GO:0072378	blood coagulation, fibrin clot formation
0.36	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading
0.36	GO:2000647	negative regulation of stem cell proliferation
0.36	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.36	GO:2000146	negative regulation of cell motility

0.69	GO:0005509	calcium ion binding
0.47	GO:0005540	hyaluronic acid binding
0.47	GO:0016504	peptidase activator activity
0.45	GO:0005201	extracellular matrix structural constituent
0.37	GO:0070051	fibrinogen binding
0.36	GO:0001968	fibronectin binding
0.36	GO:0016162	cellulose 1,4-beta-cellobiosidase activity
0.36	GO:0004222	metalloendopeptidase activity
0.36	GO:0008022	protein C-terminus binding
0.35	GO:0005272	sodium channel activity

0.49	GO:0031012	extracellular matrix
0.36	GO:0005615	extracellular space
0.33	GO:0043234	protein complex
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.36

EC:3.2.1.91

GO:0016162

tr|T1FTK3|T1FTK3_HELRO
Uncharacterized protein
Search

tr|T1FTK4|T1FTK4_HELRO
Uncharacterized protein
Search

tr|T1FTK5|T1FTK5_HELRO
Uncharacterized protein
Search

0.62	GO:0006396	RNA processing
0.43	GO:0007283	spermatogenesis
0.36	GO:0016071	mRNA metabolic process
0.35	GO:0006468	protein phosphorylation
0.35	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.34	GO:0000278	mitotic cell cycle
0.34	GO:0046939	nucleotide phosphorylation
0.34	GO:0022618	ribonucleoprotein complex assembly
0.33	GO:0051301	cell division
0.33	GO:0006508	proteolysis

0.58	GO:0003723	RNA binding
0.35	GO:0016301	kinase activity
0.35	GO:0140096	catalytic activity, acting on a protein
0.35	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0016776	phosphotransferase activity, phosphate group as acceptor
0.33	GO:0046872	metal ion binding
0.32	GO:0016787	hydrolase activity

0.37	GO:0005686	U2 snRNP
0.37	GO:0071013	catalytic step 2 spliceosome
0.37	GO:0005684	U2-type spliceosomal complex
0.36	GO:0016607	nuclear speck
0.35	GO:0071011	precatalytic spliceosome
0.34	GO:0071010	prespliceosome
0.34	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.35

GO:0016773

tr|T1FTK6|T1FTK6_HELRO
Uncharacterized protein
Search

tr|T1FTK7|T1FTK7_HELRO
Uncharacterized protein
Search

0.49

GO:0005975

carbohydrate metabolic process

0.53

GO:0004553

hydrolase activity, hydrolyzing O-glycosyl compounds

0.45	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.53

GO:0004553

tr|T1FTK8|T1FTK8_HELRO
Uncharacterized protein
Search

0.10	Tyrosine-protein kinase receptor (Fragment)

0.76	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.75	GO:0018108	peptidyl-tyrosine phosphorylation
0.66	GO:0046777	protein autophosphorylation
0.59	GO:0071469	cellular response to alkaline pH
0.49	GO:0060267	positive regulation of respiratory burst
0.49	GO:0045821	positive regulation of glycolytic process
0.49	GO:0045725	positive regulation of glycogen biosynthetic process
0.48	GO:0032148	activation of protein kinase B activity
0.48	GO:0051290	protein heterotetramerization
0.48	GO:0046326	positive regulation of glucose import

0.79	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.72	GO:0043560	insulin receptor substrate binding
0.71	GO:0043548	phosphatidylinositol 3-kinase binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0051425	PTB domain binding
0.49	GO:0043559	insulin binding
0.49	GO:0031995	insulin-like growth factor II binding

0.51	GO:0005887	integral component of plasma membrane
0.49	GO:0106003	amyloid-beta complex
0.47	GO:0005901	caveola
0.46	GO:0043235	receptor complex
0.45	GO:1902911	protein kinase complex
0.44	GO:0005635	nuclear envelope
0.42	GO:0031981	nuclear lumen
0.36	GO:0032809	neuronal cell body membrane
0.36	GO:0032590	dendrite membrane
0.36	GO:0009897	external side of plasma membrane

0.79

EC:2.7.10.1

GO:0004714

tr|T1FTK9|T1FTK9_HELRO
Uncharacterized protein
Search

tr|T1FTL0|T1FTL0_HELRO
Uncharacterized protein
Search

0.74	GO:0007018	microtubule-based movement
0.39	GO:0051256	mitotic spindle midzone assembly
0.38	GO:0000281	mitotic cytokinesis
0.35	GO:0005975	carbohydrate metabolic process
0.35	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.34	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER

0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0016887	ATPase activity
0.37	GO:0030246	carbohydrate binding
0.36	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.33	GO:0003677	DNA binding

0.49	GO:0015630	microtubule cytoskeleton
0.48	GO:0044430	cytoskeletal part
0.47	GO:0099512	supramolecular fiber
0.42	GO:0005829	cytosol
0.39	GO:0043234	protein complex
0.39	GO:0045171	intercellular bridge
0.38	GO:0005886	plasma membrane
0.36	GO:0005654	nucleoplasm
0.35	GO:0016363	nuclear matrix
0.34	GO:0030496	midbody

0.40

GO:0016887

tr|T1FTL1|T1FTL1_HELRO
Uncharacterized protein
Search

0.55	GO:0007605	sensory perception of sound
0.50	GO:0007017	microtubule-based process
0.50	GO:0002009	morphogenesis of an epithelium
0.50	GO:0007275	multicellular organism development
0.49	GO:0120036	plasma membrane bounded cell projection organization
0.47	GO:0040040	thermosensory behavior
0.47	GO:0030154	cell differentiation
0.46	GO:0007028	cytoplasm organization
0.46	GO:0008542	visual learning
0.46	GO:0006928	movement of cell or subcellular component

0.51	GO:0003779	actin binding
0.48	GO:0003777	microtubule motor activity
0.48	GO:0008017	microtubule binding
0.43	GO:0003729	mRNA binding
0.43	GO:0003700	DNA binding transcription factor activity
0.40	GO:0032559	adenyl ribonucleotide binding
0.40	GO:0003677	DNA binding
0.40	GO:0008144	drug binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding

0.53	GO:0016459	myosin complex
0.51	GO:0005634	nucleus
0.46	GO:0043186	P granule
0.46	GO:0030175	filopodium
0.45	GO:0043025	neuronal cell body
0.43	GO:0005938	cell cortex

tr|T1FTL2|T1FTL2_HELRO
Uncharacterized protein
Search

0.46	GO:0006468	protein phosphorylation
0.39	GO:0033674	positive regulation of kinase activity
0.39	GO:0016567	protein ubiquitination
0.38	GO:0045859	regulation of protein kinase activity
0.38	GO:0006417	regulation of translation
0.37	GO:0042254	ribosome biogenesis
0.36	GO:0033554	cellular response to stress
0.36	GO:0001522	pseudouridine synthesis
0.35	GO:0006508	proteolysis

0.46	GO:0004672	protein kinase activity
0.42	GO:0032555	purine ribonucleotide binding
0.42	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0030554	adenyl nucleotide binding
0.41	GO:0046872	metal ion binding
0.41	GO:0008144	drug binding
0.39	GO:0019887	protein kinase regulator activity
0.39	GO:0004842	ubiquitin-protein transferase activity
0.39	GO:0019901	protein kinase binding
0.38	GO:0043022	ribosome binding

0.35	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0044444	cytoplasmic part
0.30	GO:0016020	membrane

0.39

KEGG:R03876

GO:0004842

tr|T1FTL3|T1FTL3_HELRO
Uncharacterized protein
Search

tr|T1FTL4|T1FTL4_HELRO
Uncharacterized protein
Search

tr|T1FTL5|T1FTL5_HELRO
Uncharacterized protein
Search

tr|T1FTL6|T1FTL6_HELRO
Uncharacterized protein
Search

tr|T1FTL7|T1FTL7_HELRO
Uncharacterized protein
Search

0.48	GO:0031156	regulation of sorocarp development
0.45	GO:0043412	macromolecule modification
0.45	GO:0043326	chemotaxis to folate
0.44	GO:0043327	chemotaxis to cAMP
0.44	GO:0031272	regulation of pseudopodium assembly
0.43	GO:0032107	regulation of response to nutrient levels
0.43	GO:2001141	regulation of RNA biosynthetic process
0.43	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.42	GO:0010468	regulation of gene expression
0.42	GO:0044267	cellular protein metabolic process

0.42	GO:0004672	protein kinase activity
0.42	GO:0003676	nucleic acid binding
0.42	GO:0140110	transcription regulator activity
0.41	GO:0030554	adenyl nucleotide binding
0.41	GO:0097367	carbohydrate derivative binding
0.41	GO:0008144	drug binding
0.41	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0008641	ubiquitin-like modifier activating enzyme activity
0.40	GO:0000149	SNARE binding
0.40	GO:0008444	CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity

0.45	GO:0005634	nucleus
0.42	GO:0005881	cytoplasmic microtubule
0.42	GO:0097422	tubular endosome
0.41	GO:0005815	microtubule organizing center
0.40	GO:0042641	actomyosin
0.40	GO:0005667	transcription factor complex
0.40	GO:0005770	late endosome
0.40	GO:0005769	early endosome
0.39	GO:0030133	transport vesicle
0.37	GO:0005829	cytosol

0.40	EC:2.7.8.5	GO:0008444
0.40	KEGG:R01801	GO:0008444

tr|T1FTL8|T1FTL8_HELRO
Uncharacterized protein
Search

tr|T1FTL9|T1FTL9_HELRO
Uncharacterized protein
Search

tr|T1FTM0|T1FTM0_HELRO
Uncharacterized protein
Search

tr|T1FTM1|T1FTM1_HELRO
Uncharacterized protein
Search

0.94	Neuromacin propeptide

0.72

GO:0006952

defense response

0.49

GO:0005576

extracellular region

tr|T1FTM2|T1FTM2_HELRO
Uncharacterized protein
Search

0.59	GO:0006334	nucleosome assembly
0.47	GO:0000209	protein polyubiquitination
0.42	GO:0006974	cellular response to DNA damage stimulus
0.33	GO:0071805	potassium ion transmembrane transport
0.33	GO:0006259	DNA metabolic process

0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0046872	metal ion binding
0.48	GO:0016874	ligase activity
0.46	GO:0031625	ubiquitin protein ligase binding
0.45	GO:0004842	ubiquitin-protein transferase activity
0.45	GO:0003677	DNA binding
0.39	GO:0004386	helicase activity

0.57	GO:0000786	nucleosome
0.49	GO:0005634	nucleus
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0008076	voltage-gated potassium channel complex

0.48	EC:6	GO:0016874
0.45	KEGG:R03876	GO:0004842

tr|T1FTM3|T1FTM3_HELRO
Uncharacterized protein
Search

0.63	GO:0031175	neuron projection development
0.49	GO:0045218	zonula adherens maintenance
0.48	GO:1903358	regulation of Golgi organization
0.48	GO:0045198	establishment of epithelial cell apical/basal polarity
0.48	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity
0.48	GO:0090136	epithelial cell-cell adhesion
0.47	GO:0090109	regulation of cell-substrate junction assembly
0.47	GO:1903391	regulation of adherens junction organization
0.47	GO:0031113	regulation of microtubule polymerization
0.47	GO:0034453	microtubule anchoring

0.79	GO:0005516	calmodulin binding
0.74	GO:0008017	microtubule binding
0.69	GO:0030507	spectrin binding
0.45	GO:0051015	actin filament binding
0.35	GO:0004852	uroporphyrinogen-III synthase activity
0.35	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.34	GO:0016303	1-phosphatidylinositol-3-kinase activity
0.34	GO:0004622	lysophospholipase activity
0.33	GO:0046872	metal ion binding
0.32	GO:0005085	guanyl-nucleotide exchange factor activity

0.73	GO:0005874	microtubule
0.48	GO:0005915	zonula adherens
0.45	GO:0005813	centrosome
0.36	GO:0005737	cytoplasm
0.35	GO:0044666	MLL3/4 complex
0.34	GO:0043204	perikaryon
0.34	GO:0042383	sarcolemma
0.34	GO:0030425	dendrite
0.34	GO:0030424	axon
0.30	GO:0016021	integral component of membrane

0.35	EC:4.2.1.75	GO:0004852
0.35	KEGG:R03165	GO:0004852

tr|T1FTM4|T1FTM4_HELRO
Uncharacterized protein
Search

tr|T1FTM5|T1FTM5_HELRO
Uncharacterized protein
Search

tr|T1FTM6|T1FTM6_HELRO
Uncharacterized protein
Search

tr|T1FTM7|T1FTM7_HELRO
Uncharacterized protein
Search

HCP

0.54	Hydroxylamine reductase

0.52	GO:0055114	oxidation-reduction process
0.34	GO:0042542	response to hydrogen peroxide
0.33	GO:0006091	generation of precursor metabolites and energy
0.33	GO:0098869	cellular oxidant detoxification
0.31	GO:0006807	nitrogen compound metabolic process

0.81	GO:0050418	hydroxylamine reductase activity
0.64	GO:0051540	metal cluster binding
0.55	GO:0048037	cofactor binding
0.52	GO:0046872	metal ion binding
0.34	GO:0018492	carbon-monoxide dehydrogenase (acceptor) activity
0.34	GO:0009055	electron transfer activity
0.33	GO:0097367	carbohydrate derivative binding
0.33	GO:0004601	peroxidase activity
0.33	GO:0043168	anion binding
0.33	GO:1901265	nucleoside phosphate binding

0.49

GO:0005737

cytoplasm

0.81	EC:1.7.99.1	GO:0050418
0.33	KEGG:R03532	GO:0004601

tr|T1FTM8|T1FTM8_HELRO
Uncharacterized protein
Search

0.35	GO:0031648	protein destabilization
0.35	GO:1900176	negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry
0.33	GO:0006508	proteolysis
0.32	GO:0098655	cation transmembrane transport

0.69	GO:0030246	carbohydrate binding
0.34	GO:0004180	carboxypeptidase activity
0.32	GO:0005515	protein binding
0.32	GO:0008324	cation transmembrane transporter activity

0.35	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1FTM9|T1FTM9_HELRO
Uncharacterized protein
Search

tr|T1FTN0|T1FTN0_HELRO
Uncharacterized protein
Search

DNAJC5

0.95	DnaJ like protein subfamily C member 5

0.77	GO:0043524	negative regulation of neuron apoptotic process
0.41	GO:0007268	chemical synaptic transmission
0.40	GO:0043312	neutrophil degranulation
0.39	GO:0017156	calcium ion regulated exocytosis
0.39	GO:0097480	establishment of synaptic vesicle localization
0.39	GO:0099504	synaptic vesicle cycle
0.39	GO:0099003	vesicle-mediated transport in synapse
0.39	GO:0099643	signal release from synapse
0.38	GO:0006836	neurotransmitter transport
0.37	GO:0001505	regulation of neurotransmitter levels

0.47

GO:0043008

ATP-dependent protein binding

0.75	GO:0008021	synaptic vesicle
0.53	GO:0005886	plasma membrane
0.48	GO:0042470	melanosome
0.46	GO:0043195	terminal bouton
0.43	GO:0030667	secretory granule membrane
0.42	GO:0005765	lysosomal membrane
0.42	GO:0070062	extracellular exosome
0.41	GO:0061200	clathrin-sculpted gamma-aminobutyric acid transport vesicle
0.40	GO:0042583	chromaffin granule
0.40	GO:0005766	primary lysosome

tr|T1FTN1|T1FTN1_HELRO
Uncharacterized protein
Search

tr|T1FTN2|T1FTN2_HELRO
Uncharacterized protein
Search

0.71	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 (Fragment)

0.81	GO:0046856	phosphatidylinositol dephosphorylation
0.52	GO:0045659	negative regulation of neutrophil differentiation
0.52	GO:0045409	negative regulation of interleukin-6 biosynthetic process
0.52	GO:0045656	negative regulation of monocyte differentiation
0.51	GO:0045779	negative regulation of bone resorption
0.51	GO:0045579	positive regulation of B cell differentiation
0.51	GO:0030889	negative regulation of B cell proliferation
0.51	GO:0045671	negative regulation of osteoclast differentiation
0.50	GO:0045648	positive regulation of erythrocyte differentiation
0.49	GO:0016064	immunoglobulin mediated immune response

0.52	GO:0051425	PTB domain binding
0.52	GO:0004445	inositol-polyphosphate 5-phosphatase activity
0.51	GO:0034594	phosphatidylinositol trisphosphate phosphatase activity
0.48	GO:0017124	SH3 domain binding
0.43	GO:0042169	SH2 domain binding
0.35	GO:0003779	actin binding
0.35	GO:0030487	inositol-4,5-bisphosphate 5-phosphatase activity
0.35	GO:0052659	inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity
0.34	GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity
0.33	GO:0001608	G-protein coupled nucleotide receptor activity

0.48	GO:0005829	cytosol
0.40	GO:0005794	Golgi apparatus
0.37	GO:0005886	plasma membrane
0.36	GO:0098857	membrane microdomain
0.36	GO:0005856	cytoskeleton
0.36	GO:0030175	filopodium
0.35	GO:0030027	lamellipodium
0.34	GO:0005680	anaphase-promoting complex
0.34	GO:0044448	cell cortex part
0.33	GO:0099512	supramolecular fiber

0.52	EC:3.1.3.56	GO:0004445
0.35	KEGG:R03430	GO:0052659

tr|T1FTN3|T1FTN3_HELRO
Uncharacterized protein
Search

tr|T1FTN4|T1FTN4_HELRO
Uncharacterized protein
Search

tr|T1FTN5|T1FTN5_HELRO
Uncharacterized protein
Search

0.57

GO:0005509

calcium ion binding

0.30

GO:0044425

membrane part

tr|T1FTN6|T1FTN6_HELRO
Uncharacterized protein
Search

0.35	GO:0010256	endomembrane system organization
0.35	GO:0070868	heterochromatin organization involved in chromatin silencing
0.35	GO:0031935	regulation of chromatin silencing
0.35	GO:0007476	imaginal disc-derived wing morphogenesis
0.35	GO:0030178	negative regulation of Wnt signaling pathway
0.34	GO:0045931	positive regulation of mitotic cell cycle
0.34	GO:0061024	membrane organization
0.34	GO:0006357	regulation of transcription by RNA polymerase II
0.34	GO:0007155	cell adhesion
0.33	GO:0006607	NLS-bearing protein import into nucleus

0.50	GO:0003676	nucleic acid binding
0.35	GO:0005515	protein binding
0.34	GO:0008270	zinc ion binding
0.33	GO:0004386	helicase activity
0.33	GO:0005524	ATP binding
0.33	GO:0017056	structural constituent of nuclear pore
0.33	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.32	GO:0016301	kinase activity
0.32	GO:0016853	isomerase activity

0.49	GO:0005654	nucleoplasm
0.34	GO:0000792	heterochromatin
0.33	GO:0044613	nuclear pore central transport channel
0.30	GO:0031224	intrinsic component of membrane

0.32	EC:5	GO:0016853
0.33	KEGG:R03876	GO:0004842

tr|T1FTN7|T1FTN7_HELRO
Uncharacterized protein
Search

0.65	Phosphatidylinositol-binding clathrin assembly protein LAP

0.83	GO:0048268	clathrin coat assembly
0.36	GO:0048488	synaptic vesicle endocytosis
0.35	GO:0007268	chemical synaptic transmission
0.35	GO:2000370	positive regulation of clathrin-dependent endocytosis
0.35	GO:0042331	phototaxis
0.34	GO:0048489	synaptic vesicle transport
0.34	GO:0099643	signal release from synapse
0.33	GO:0006898	receptor-mediated endocytosis
0.33	GO:0006836	neurotransmitter transport
0.33	GO:0001505	regulation of neurotransmitter levels

0.84	GO:0005545	1-phosphatidylinositol binding
0.81	GO:0030276	clathrin binding
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity

0.80	GO:0030136	clathrin-coated vesicle
0.35	GO:0045202	synapse
0.34	GO:0005905	clathrin-coated pit
0.33	GO:0005794	Golgi apparatus
0.33	GO:0097458	neuron part

0.34

EC:1.3.1.74

GO:0032440

tr|T1FTN8|T1FTN8_HELRO
Uncharacterized protein
Search

IFT57

0.91	Intraflagellar transport protein 57

0.59	GO:1905515	non-motile cilium assembly
0.58	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.58	GO:0007368	determination of left/right symmetry
0.56	GO:0060972	left/right pattern formation
0.56	GO:0044458	motile cilium assembly
0.55	GO:0003143	embryonic heart tube morphogenesis
0.55	GO:0001843	neural tube closure
0.55	GO:0050680	negative regulation of epithelial cell proliferation
0.55	GO:0042073	intraciliary transport
0.55	GO:0006915	apoptotic process

0.34	GO:0005515	protein binding
0.34	GO:0003677	DNA binding

0.72	GO:0005929	cilium
0.59	GO:0030992	intraciliary transport particle B
0.57	GO:0044292	dendrite terminus
0.55	GO:0005813	centrosome
0.54	GO:0032838	plasma membrane bounded cell projection cytoplasm
0.52	GO:0005794	Golgi apparatus
0.30	GO:0016020	membrane

tr|T1FTN9|T1FTN9_HELRO
Uncharacterized protein
Search

0.53	GO:0007221	positive regulation of transcription of Notch receptor target
0.52	GO:0060412	ventricular septum morphogenesis
0.52	GO:0001569	branching involved in blood vessel morphogenesis
0.52	GO:0048536	spleen development
0.51	GO:0045638	negative regulation of myeloid cell differentiation
0.50	GO:0060674	placenta blood vessel development
0.48	GO:0000122	negative regulation of transcription by RNA polymerase II
0.41	GO:0000398	mRNA splicing, via spliceosome
0.36	GO:0051260	protein homooligomerization
0.36	GO:0071805	potassium ion transmembrane transport

0.59	GO:0003723	RNA binding
0.37	GO:0005515	protein binding
0.36	GO:0005249	voltage-gated potassium channel activity
0.33	GO:0043565	sequence-specific DNA binding

0.50	GO:0016607	nuclear speck
0.36	GO:0008076	voltage-gated potassium channel complex
0.35	GO:0031965	nuclear membrane

tr|T1FTP0|T1FTP0_HELRO
Uncharacterized protein
Search

0.44	GO:0060255	regulation of macromolecule metabolic process
0.44	GO:0080090	regulation of primary metabolic process
0.44	GO:0031323	regulation of cellular metabolic process
0.44	GO:0051171	regulation of nitrogen compound metabolic process
0.43	GO:0036211	protein modification process
0.43	GO:0009889	regulation of biosynthetic process
0.42	GO:0051346	negative regulation of hydrolase activity
0.42	GO:0048523	negative regulation of cellular process
0.41	GO:0006511	ubiquitin-dependent protein catabolic process
0.40	GO:0006289	nucleotide-excision repair

0.50	GO:0005509	calcium ion binding
0.45	GO:0003700	DNA binding transcription factor activity
0.43	GO:0140096	catalytic activity, acting on a protein
0.43	GO:0004867	serine-type endopeptidase inhibitor activity
0.41	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.41	GO:0016301	kinase activity
0.40	GO:0032559	adenyl ribonucleotide binding
0.40	GO:0008022	protein C-terminus binding
0.40	GO:0008144	drug binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding

0.48	GO:0005604	basement membrane
0.46	GO:0005938	cell cortex
0.45	GO:0030054	cell junction
0.44	GO:0005615	extracellular space
0.43	GO:1903561	extracellular vesicle
0.41	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.41

GO:0016773

tr|T1FTP1|T1FTP1_HELRO
Uncharacterized protein
Search

0.67	GO:0030968	endoplasmic reticulum unfolded protein response
0.62	GO:0045944	positive regulation of transcription by RNA polymerase II
0.51	GO:0002062	chondrocyte differentiation
0.48	GO:0006888	ER to Golgi vesicle-mediated transport
0.47	GO:0006366	transcription by RNA polymerase II
0.42	GO:0035293	chitin-based larval cuticle pattern formation
0.41	GO:0007431	salivary gland development
0.40	GO:0009953	dorsal/ventral pattern formation
0.39	GO:0042981	regulation of apoptotic process

0.69	GO:0035497	cAMP response element binding
0.61	GO:0003700	DNA binding transcription factor activity
0.41	GO:0001158	enhancer sequence-specific DNA binding

0.49	GO:0005634	nucleus
0.46	GO:0005783	endoplasmic reticulum
0.45	GO:0043233	organelle lumen
0.41	GO:0044446	intracellular organelle part
0.40	GO:0005700	polytene chromosome
0.36	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0005794	Golgi apparatus
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

tr|T1FTP2|T1FTP2_HELRO
Uncharacterized protein
Search

0.54	GO:1902600	hydrogen ion transmembrane transport
0.40	GO:0007020	microtubule nucleation
0.39	GO:0006281	DNA repair
0.38	GO:0031323	regulation of cellular metabolic process
0.38	GO:0051171	regulation of nitrogen compound metabolic process
0.38	GO:0060255	regulation of macromolecule metabolic process
0.38	GO:0080090	regulation of primary metabolic process
0.38	GO:0009889	regulation of biosynthetic process
0.37	GO:0006511	ubiquitin-dependent protein catabolic process
0.36	GO:0016567	protein ubiquitination

0.62	GO:0015299	solute:proton antiporter activity
0.41	GO:0043015	gamma-tubulin binding
0.39	GO:0003700	DNA binding transcription factor activity
0.37	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.36	GO:0004842	ubiquitin-protein transferase activity
0.36	GO:0003676	nucleic acid binding
0.35	GO:0003777	microtubule motor activity
0.35	GO:0046872	metal ion binding
0.34	GO:0003843	1,3-beta-D-glucan synthase activity
0.34	GO:0005518	collagen binding

0.40	GO:0000922	spindle pole
0.39	GO:0005815	microtubule organizing center
0.38	GO:0005634	nucleus
0.35	GO:1902494	catalytic complex
0.35	GO:0043234	protein complex
0.34	GO:0005576	extracellular region
0.33	GO:0032155	cell division site part
0.33	GO:0044444	cytoplasmic part
0.33	GO:0044459	plasma membrane part
0.32	GO:0030529	intracellular ribonucleoprotein complex

0.37	EC:3.4.19.12	GO:0036459
0.36	KEGG:R03876	GO:0004842

tr|T1FTP3|T1FTP3_HELRO
Uncharacterized protein
Search

tr|T1FTP4|T1FTP4_HELRO
Uncharacterized protein
Search

tr|T1FTP5|T1FTP5_HELRO
Uncharacterized protein
Search

0.60	GO:0007016	cytoskeletal anchoring at plasma membrane
0.43	GO:0036211	protein modification process
0.41	GO:0044267	cellular protein metabolic process
0.40	GO:0010468	regulation of gene expression
0.39	GO:0016071	mRNA metabolic process
0.39	GO:0031323	regulation of cellular metabolic process
0.39	GO:0051171	regulation of nitrogen compound metabolic process
0.39	GO:0080090	regulation of primary metabolic process
0.39	GO:0010556	regulation of macromolecule biosynthetic process
0.38	GO:0016569	covalent chromatin modification

0.40	GO:0004672	protein kinase activity
0.40	GO:0003676	nucleic acid binding
0.38	GO:0003700	DNA binding transcription factor activity
0.38	GO:0030554	adenyl nucleotide binding
0.38	GO:0043168	anion binding
0.38	GO:0032555	purine ribonucleotide binding
0.38	GO:0008144	drug binding
0.38	GO:0102965	alcohol-forming fatty acyl-CoA reductase activity
0.38	GO:0005515	protein binding
0.38	GO:0008047	enzyme activator activity

0.59	GO:0016010	dystrophin-associated glycoprotein complex
0.44	GO:0005634	nucleus
0.38	GO:0044446	intracellular organelle part
0.37	GO:0099512	supramolecular fiber
0.37	GO:0030136	clathrin-coated vesicle
0.37	GO:0048476	Holliday junction resolvase complex
0.37	GO:0030015	CCR4-NOT core complex
0.37	GO:0005856	cytoskeleton
0.36	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0005667	transcription factor complex

0.37	EC:4.2.3.5	GO:0004107
0.37	KEGG:R01714	GO:0004107

tr|T1FTP6|T1FTP6_HELRO
Uncharacterized protein
Search

tr|T1FTP7|T1FTP7_HELRO
Uncharacterized protein
Search

0.52	GO:0055114	oxidation-reduction process
0.49	GO:0070813	hydrogen sulfide metabolic process
0.49	GO:0000103	sulfate assimilation
0.49	GO:0006534	cysteine metabolic process
0.49	GO:0000097	sulfur amino acid biosynthetic process
0.48	GO:0009403	toxin biosynthetic process
0.47	GO:0009070	serine family amino acid biosynthetic process
0.43	GO:1904042	negative regulation of cystathionine beta-synthase activity
0.42	GO:0043418	homocysteine catabolic process
0.40	GO:0046655	folic acid metabolic process

0.67	GO:0010181	FMN binding
0.54	GO:0016491	oxidoreductase activity
0.47	GO:0050660	flavin adenine dinucleotide binding
0.40	GO:0070402	NADPH binding
0.34	GO:0043565	sequence-specific DNA binding
0.34	GO:0003700	DNA binding transcription factor activity
0.33	GO:0020037	heme binding
0.33	GO:0005506	iron ion binding

0.34	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0005737	cytoplasm
0.34	GO:0031968	organelle outer membrane
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0031984	organelle subcompartment
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.54

GO:0016491

tr|T1FTP8|T1FTP8_HELRO
Uncharacterized protein
Search

tr|T1FTP9|T1FTP9_HELRO
Uncharacterized protein
Search

tr|T1FTQ0|T1FTQ0_HELRO
Uncharacterized protein
Search

tr|T1FTQ1|T1FTQ1_HELRO
Uncharacterized protein
Search

0.49	Ubiquilin-1

0.81	GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process
0.77	GO:1904294	positive regulation of ERAD pathway
0.72	GO:0016241	regulation of macroautophagy
0.70	GO:0030433	ubiquitin-dependent ERAD pathway
0.69	GO:0051051	negative regulation of transport
0.66	GO:0051129	negative regulation of cellular component organization
0.66	GO:1904020	regulation of G-protein coupled receptor internalization
0.64	GO:0033043	regulation of organelle organization
0.64	GO:0035973	aggrephagy
0.63	GO:2000369	regulation of clathrin-dependent endocytosis

0.73	GO:0031593	polyubiquitin modification-dependent protein binding
0.63	GO:0042802	identical protein binding
0.55	GO:0019900	kinase binding
0.35	GO:0003676	nucleic acid binding

0.72	GO:0005776	autophagosome
0.66	GO:0005829	cytosol
0.62	GO:0031595	nuclear proteasome complex
0.61	GO:0005783	endoplasmic reticulum
0.61	GO:0016235	aggresome
0.57	GO:0048471	perinuclear region of cytoplasm
0.53	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.52	GO:0005654	nucleoplasm
0.50	GO:0031984	organelle subcompartment
0.50	GO:0005886	plasma membrane

tr|T1FTQ2|T1FTQ2_HELRO
SURF1-like protein
Search

0.44	GO:0033617	mitochondrial respiratory chain complex IV assembly
0.40	GO:0006754	ATP biosynthetic process
0.40	GO:1902600	hydrogen ion transmembrane transport
0.39	GO:0006091	generation of precursor metabolites and energy
0.39	GO:0021522	spinal cord motor neuron differentiation
0.38	GO:0048568	embryonic organ development
0.37	GO:0016310	phosphorylation
0.37	GO:0055114	oxidation-reduction process
0.36	GO:0034498	early endosome to Golgi transport
0.35	GO:0032527	protein exit from endoplasmic reticulum

0.40	GO:0015002	heme-copper terminal oxidase activity
0.40	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.40	GO:0015078	hydrogen ion transmembrane transporter activity
0.39	GO:0009055	electron transfer activity
0.33	GO:0005515	protein binding
0.32	GO:0030246	carbohydrate binding

0.61	GO:0031966	mitochondrial membrane
0.61	GO:0019866	organelle inner membrane
0.35	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.33	GO:0070469	respiratory chain
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.40

EC:1.9.3

GO:0016676

tr|T1FTQ3|T1FTQ3_HELRO
Uncharacterized protein
Search

0.30

GO:0044425

membrane part

tr|T1FTQ4|T1FTQ4_HELRO
Uncharacterized protein
Search

0.37	Splicing factor

0.81	GO:0043484	regulation of RNA splicing
0.64	GO:0006281	DNA repair
0.39	GO:0001745	compound eye morphogenesis
0.38	GO:0050684	regulation of mRNA processing
0.34	GO:0016567	protein ubiquitination
0.34	GO:0000398	mRNA splicing, via spliceosome
0.33	GO:0005975	carbohydrate metabolic process
0.33	GO:0006351	transcription, DNA-templated
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.58	GO:0003723	RNA binding
0.34	GO:0004842	ubiquitin-protein transferase activity
0.34	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.34	GO:0050660	flavin adenine dinucleotide binding
0.33	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors
0.33	GO:0046872	metal ion binding
0.33	GO:0043565	sequence-specific DNA binding
0.33	GO:0003700	DNA binding transcription factor activity

0.37	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.34	EC:3.2.1	GO:0004553
0.34	KEGG:R03876	GO:0004842

tr|T1FTQ5|T1FTQ5_HELRO
Uncharacterized protein
Search

tr|T1FTQ6|T1FTQ6_HELRO
Uncharacterized protein
Search

tr|T1FTQ7|T1FTQ7_HELRO
Uncharacterized protein
Search

tr|T1FTQ8|T1FTQ8_HELRO
Uncharacterized protein
Search

tr|T1FTQ9|T1FTQ9_HELRO
Uncharacterized protein
Search

tr|T1FTR0|T1FTR0_HELRO
Uncharacterized protein
Search

0.10	Craniofacial development protein 1

0.58	GO:0010032	meiotic chromosome condensation
0.57	GO:2000615	regulation of histone H3-K9 acetylation
0.57	GO:0051570	regulation of histone H3-K9 methylation
0.56	GO:0051569	regulation of histone H3-K4 methylation
0.54	GO:0007076	mitotic chromosome condensation
0.49	GO:0048856	anatomical structure development
0.48	GO:0032501	multicellular organismal process
0.48	GO:0043968	histone H2A acetylation
0.47	GO:0043967	histone H4 acetylation
0.47	GO:0006338	chromatin remodeling

0.56	GO:0019894	kinesin binding
0.40	GO:0003735	structural constituent of ribosome
0.39	GO:0032550	purine ribonucleoside binding
0.38	GO:0019001	guanyl nucleotide binding
0.38	GO:0008168	methyltransferase activity
0.38	GO:0005179	hormone activity
0.36	GO:0032555	purine ribonucleotide binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0003677	DNA binding
0.35	GO:0016301	kinase activity

0.56	GO:0005694	chromosome
0.50	GO:0005634	nucleus
0.49	GO:0044446	intracellular organelle part
0.47	GO:0070701	mucus layer
0.47	GO:0043234	protein complex
0.46	GO:0043233	organelle lumen
0.45	GO:0031248	protein acetyltransferase complex
0.42	GO:0022626	cytosolic ribosome
0.38	GO:0033202	DNA helicase complex
0.36	GO:1904949	ATPase complex

0.38

GO:0008168

tr|T1FTR1|T1FTR1_HELRO
Uncharacterized protein
Search

tr|T1FTR2|T1FTR2_HELRO
Uncharacterized protein
Search

tr|T1FTR3|T1FTR3_HELRO
Uncharacterized protein
Search

tr|T1FTR4|T1FTR4_HELRO
Uncharacterized protein
Search

tr|T1FTR5|T1FTR5_HELRO
Uncharacterized protein
Search

tr|T1FTR6|T1FTR6_HELRO
Uncharacterized protein
Search

0.71	GO:0000724	double-strand break repair via homologous recombination
0.36	GO:0008585	female gonad development
0.36	GO:0007530	sex determination
0.36	GO:0007283	spermatogenesis
0.35	GO:0005978	glycogen biosynthetic process
0.35	GO:2001141	regulation of RNA biosynthetic process
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression
0.34	GO:0006904	vesicle docking involved in exocytosis
0.33	GO:0007155	cell adhesion

0.38	GO:0046982	protein heterodimerization activity
0.36	GO:0003700	DNA binding transcription factor activity
0.36	GO:0004373	glycogen (starch) synthase activity
0.35	GO:0003676	nucleic acid binding
0.35	GO:0046872	metal ion binding
0.34	GO:0008061	chitin binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.38	GO:0016602	CCAAT-binding factor complex
0.35	GO:0005680	anaphase-promoting complex
0.34	GO:0008305	integrin complex

0.36

EC:2.4.1.11

GO:0004373

tr|T1FTR7|T1FTR7_HELRO
Uncharacterized protein
Search

CTBS

0.84	Di-N-acetylchitobiase

0.60	GO:0005975	carbohydrate metabolic process
0.48	GO:0006032	chitin catabolic process
0.35	GO:0006869	lipid transport
0.33	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:0036065	fucosylation
0.32	GO:0043413	macromolecule glycosylation
0.32	GO:0009101	glycoprotein biosynthetic process
0.32	GO:0009253	peptidoglycan catabolic process
0.32	GO:0036211	protein modification process
0.32	GO:0044267	cellular protein metabolic process

0.76	GO:0008061	chitin binding
0.64	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.35	GO:0005319	lipid transporter activity
0.33	GO:0030246	carbohydrate binding
0.33	GO:0004871	signal transducer activity
0.33	GO:0008417	fucosyltransferase activity
0.32	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity

0.43	GO:0005576	extracellular region
0.38	GO:0005764	lysosome
0.35	GO:0031982	vesicle
0.34	GO:1905360	GTPase complex
0.34	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.33	GO:0098797	plasma membrane protein complex
0.33	GO:0032580	Golgi cisterna membrane
0.30	GO:0016021	integral component of membrane

0.64

GO:0004553

tr|T1FTR8|T1FTR8_HELRO
Uncharacterized protein
Search

0.78	GO:0007030	Golgi organization
0.66	GO:0034497	protein localization to phagophore assembly site
0.65	GO:0032258	protein localization by the Cvt pathway
0.65	GO:0030242	autophagy of peroxisome
0.65	GO:0044804	autophagy of nucleus
0.60	GO:0006888	ER to Golgi vesicle-mediated transport
0.37	GO:0051568	histone H3-K4 methylation
0.36	GO:0065009	regulation of molecular function
0.35	GO:0006351	transcription, DNA-templated
0.35	GO:1903506	regulation of nucleic acid-templated transcription

0.39	GO:0017112	Rab guanyl-nucleotide exchange factor activity
0.37	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.37	GO:0046983	protein dimerization activity
0.36	GO:0003700	DNA binding transcription factor activity
0.35	GO:0003677	DNA binding
0.33	GO:0046872	metal ion binding

0.80	GO:0030008	TRAPP complex
0.63	GO:0000407	phagophore assembly site
0.57	GO:0044431	Golgi apparatus part
0.57	GO:0031410	cytoplasmic vesicle
0.38	GO:0005667	transcription factor complex
0.37	GO:0005634	nucleus
0.37	GO:0005829	cytosol
0.36	GO:0034708	methyltransferase complex
0.35	GO:0043233	organelle lumen

tr|T1FTR9|T1FTR9_HELRO
Uncharacterized protein
Search

0.77	GO:0072488	ammonium transmembrane transport
0.48	GO:0015695	organic cation transport

0.77

GO:0008519

ammonium transmembrane transporter activity

0.44

GO:0005887

integral component of plasma membrane

tr|T1FTS0|T1FTS0_HELRO
Uncharacterized protein
Search

tr|T1FTS1|T1FTS1_HELRO
Uncharacterized protein
Search

0.77	ADP-ribosylation factor-like protein 6-interacting protein 4

0.61

GO:0005634

nucleus

tr|T1FTS2|T1FTS2_HELRO
Uncharacterized protein
Search

0.85	GO:0031087	deadenylation-independent decapping of nuclear-transcribed mRNA
0.48	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.47	GO:0033962	cytoplasmic mRNA processing body assembly
0.34	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
0.34	GO:0034968	histone lysine methylation
0.33	GO:0006468	protein phosphorylation
0.33	GO:0055114	oxidation-reduction process
0.32	GO:0006351	transcription, DNA-templated
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:2001141	regulation of RNA biosynthetic process

0.74	GO:0003729	mRNA binding
0.57	GO:1990174	phosphodiesterase decapping endonuclease activity
0.48	GO:0042802	identical protein binding
0.35	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.34	GO:0018024	histone-lysine N-methyltransferase activity
0.34	GO:0046914	transition metal ion binding
0.34	GO:0020037	heme binding
0.33	GO:0004672	protein kinase activity
0.33	GO:0043565	sequence-specific DNA binding
0.32	GO:0003700	DNA binding transcription factor activity

0.53	GO:0036464	cytoplasmic ribonucleoprotein granule
0.33	GO:0005829	cytosol
0.32	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.35

EC:1.14.14

GO:0016712

tr|T1FTS3|T1FTS3_HELRO
Uncharacterized protein
Search

tr|T1FTS4|T1FTS4_HELRO
Bestrophin homolog
Search

0.37	Bestrophin homolog

0.75	GO:1902476	chloride transmembrane transport
0.53	GO:0007601	visual perception
0.38	GO:0045332	phospholipid translocation
0.34	GO:0055114	oxidation-reduction process

0.76	GO:0005254	chloride channel activity
0.38	GO:0004012	phospholipid-translocating ATPase activity
0.37	GO:0010181	FMN binding
0.35	GO:0000287	magnesium ion binding
0.34	GO:0016491	oxidoreductase activity
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.80	GO:0034707	chloride channel complex
0.55	GO:0005886	plasma membrane

0.38

EC:3.6.3.1

GO:0004012

tr|T1FTS5|T1FTS5_HELRO
Uncharacterized protein
Search

tr|T1FTS6|T1FTS6_HELRO
Uncharacterized protein
Search

0.48	GO:0051568	histone H3-K4 methylation
0.43	GO:0007094	mitotic spindle assembly checkpoint
0.41	GO:0044265	cellular macromolecule catabolic process
0.40	GO:0030163	protein catabolic process
0.40	GO:0006468	protein phosphorylation
0.39	GO:0010556	regulation of macromolecule biosynthetic process
0.39	GO:0031326	regulation of cellular biosynthetic process
0.39	GO:0051171	regulation of nitrogen compound metabolic process
0.39	GO:0080090	regulation of primary metabolic process
0.39	GO:0006508	proteolysis

0.49	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.41	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.41	GO:0003676	nucleic acid binding
0.41	GO:0016301	kinase activity
0.39	GO:0046872	metal ion binding
0.39	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.39	GO:0050825	ice binding
0.38	GO:0140110	transcription regulator activity
0.37	GO:0030554	adenyl nucleotide binding
0.37	GO:0045735	nutrient reservoir activity

0.47	GO:0035097	histone methyltransferase complex
0.41	GO:0031213	RSF complex
0.40	GO:0000123	histone acetyltransferase complex
0.39	GO:1905368	peptidase complex
0.38	GO:0043234	protein complex
0.37	GO:0000932	P-body
0.30	GO:0016020	membrane

0.41

EC:3.4.19.12

GO:0036459

tr|T1FTS7|T1FTS7_HELRO
Uncharacterized protein
Search

0.34	GO:0043414	macromolecule methylation
0.34	GO:0016570	histone modification
0.34	GO:0018205	peptidyl-lysine modification
0.34	GO:0008213	protein alkylation
0.33	GO:0000154	rRNA modification

0.78	GO:0008201	heparin binding
0.56	GO:0046914	transition metal ion binding
0.34	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity
0.34	GO:0042054	histone methyltransferase activity
0.34	GO:0008170	N-methyltransferase activity
0.33	GO:0140102	catalytic activity, acting on a rRNA
0.33	GO:0008173	RNA methyltransferase activity
0.33	GO:0016874	ligase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding

0.34	GO:0005730	nucleolus
0.30	GO:0016020	membrane

0.34

GO:0008170

tr|T1FTS8|T1FTS8_HELRO
Uncharacterized protein
Search

0.10	RNA recognition motif domain containing protein

0.37	GO:0000398	mRNA splicing, via spliceosome
0.35	GO:0035206	regulation of hemocyte proliferation
0.35	GO:0022611	dormancy process
0.34	GO:0018108	peptidyl-tyrosine phosphorylation
0.34	GO:0007268	chemical synaptic transmission
0.34	GO:0007275	multicellular organism development
0.34	GO:0006457	protein folding

0.59	GO:0003723	RNA binding
0.35	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.34	GO:0031072	heat shock protein binding
0.34	GO:0042803	protein homodimerization activity
0.34	GO:0051082	unfolded protein binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0046872	metal ion binding

0.38	GO:0005685	U1 snRNP
0.30	GO:0016020	membrane

0.35

EC:2.7.10.2

GO:0004715

tr|T1FTS9|T1FTS9_HELRO
Uncharacterized protein
Search

0.53	GO:0007482	haltere development
0.53	GO:0045433	male courtship behavior, veined wing generated song production
0.53	GO:0007526	larval somatic muscle development
0.52	GO:0002168	instar larval development
0.51	GO:0007591	molting cycle, chitin-based cuticle
0.40	GO:2001141	regulation of RNA biosynthetic process
0.40	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.40	GO:0010468	regulation of gene expression

0.44	GO:0032559	adenyl ribonucleotide binding
0.44	GO:0008144	drug binding
0.44	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0003700	DNA binding transcription factor activity
0.39	GO:0046872	metal ion binding
0.39	GO:0016787	hydrolase activity

0.42	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.39

GO:0016787

tr|T1FTT0|T1FTT0_HELRO
Uncharacterized protein
Search

0.46	GO:2001141	regulation of RNA biosynthetic process
0.46	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.46	GO:0010468	regulation of gene expression
0.43	GO:0016042	lipid catabolic process
0.38	GO:0055114	oxidation-reduction process
0.38	GO:0051781	positive regulation of cell division
0.38	GO:0048639	positive regulation of developmental growth
0.38	GO:0007444	imaginal disc development
0.38	GO:0008361	regulation of cell size
0.37	GO:0010467	gene expression

0.49	GO:0140110	transcription regulator activity
0.40	GO:0046872	metal ion binding
0.39	GO:0016491	oxidoreductase activity
0.39	GO:0008157	protein phosphatase 1 binding
0.38	GO:0003676	nucleic acid binding
0.38	GO:0016787	hydrolase activity
0.37	GO:0008140	cAMP response element binding protein binding
0.36	GO:0008168	methyltransferase activity
0.35	GO:0017076	purine nucleotide binding
0.35	GO:0097367	carbohydrate derivative binding

0.41	GO:0005634	nucleus
0.39	GO:0070013	intracellular organelle lumen
0.39	GO:0032433	filopodium tip
0.37	GO:0044446	intracellular organelle part
0.37	GO:0043234	protein complex
0.36	GO:1902494	catalytic complex
0.36	GO:0043232	intracellular non-membrane-bounded organelle
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.39

GO:0016491

tr|T1FTT1|T1FTT1_HELRO
Uncharacterized protein
Search

0.49

GO:0071528

tRNA re-export from nucleus

0.53	GO:0008536	Ran GTPase binding
0.41	GO:0000049	tRNA binding

0.61	GO:0005634	nucleus
0.41	GO:0031974	membrane-enclosed lumen
0.41	GO:0012505	endomembrane system
0.39	GO:0031967	organelle envelope
0.39	GO:0043234	protein complex
0.37	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

tr|T1FTT2|T1FTT2_HELRO
Uncharacterized protein
Search

0.61	GO:0001558	regulation of cell growth
0.43	GO:0006338	chromatin remodeling
0.38	GO:0007160	cell-matrix adhesion
0.37	GO:0060255	regulation of macromolecule metabolic process
0.37	GO:0031323	regulation of cellular metabolic process
0.37	GO:0051171	regulation of nitrogen compound metabolic process
0.37	GO:0080090	regulation of primary metabolic process
0.37	GO:0021999	neural plate anterior/posterior regionalization
0.36	GO:0019538	protein metabolic process
0.36	GO:0010467	gene expression

0.64	GO:0005520	insulin-like growth factor binding
0.44	GO:0045735	nutrient reservoir activity
0.38	GO:0008658	penicillin binding
0.37	GO:0003713	transcription coactivator activity
0.37	GO:0050825	ice binding
0.36	GO:0003676	nucleic acid binding
0.36	GO:0016740	transferase activity
0.36	GO:0140034	methylation-dependent protein binding
0.35	GO:0005525	GTP binding
0.35	GO:0019901	protein kinase binding

0.54	GO:0005576	extracellular region
0.43	GO:0070603	SWI/SNF superfamily-type complex
0.42	GO:0033202	DNA helicase complex
0.38	GO:1990234	transferase complex
0.37	GO:0044451	nucleoplasm part
0.36	GO:0043234	protein complex
0.36	GO:0042600	chorion
0.35	GO:0000137	Golgi cis cisterna
0.35	GO:0030173	integral component of Golgi membrane
0.35	GO:0030686	90S preribosome

0.36

GO:0016740

tr|T1FTT3|T1FTT3_HELRO
Uncharacterized protein
Search

tr|T1FTT4|T1FTT4_HELRO
Uncharacterized protein
Search

0.54	GO:0006261	DNA-dependent DNA replication
0.52	GO:0071897	DNA biosynthetic process
0.43	GO:0008608	attachment of spindle microtubules to kinetochore
0.43	GO:0051983	regulation of chromosome segregation
0.42	GO:0000070	mitotic sister chromatid segregation
0.40	GO:0071173	spindle assembly checkpoint
0.39	GO:0045839	negative regulation of mitotic nuclear division
0.39	GO:2001251	negative regulation of chromosome organization
0.39	GO:1901991	negative regulation of mitotic cell cycle phase transition
0.39	GO:0007093	mitotic cell cycle checkpoint

0.54	GO:0003887	DNA-directed DNA polymerase activity
0.42	GO:0003677	DNA binding
0.39	GO:0043130	ubiquitin binding
0.38	GO:0008409	5'-3' exonuclease activity
0.38	GO:0003729	mRNA binding

0.42	GO:0000776	kinetochore
0.41	GO:1990298	bub1-bub3 complex
0.41	GO:0033597	mitotic checkpoint complex
0.39	GO:0000445	THO complex part of transcription export complex
0.38	GO:0032300	mismatch repair complex
0.33	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.54

GO:0003887

tr|T1FTT5|T1FTT5_HELRO
Uncharacterized protein
Search

tr|T1FTT6|T1FTT6_HELRO
Uncharacterized protein
Search

0.25	Glycerophosphoryl diester phosphodiesterase

0.63	GO:0006629	lipid metabolic process
0.37	GO:0016311	dephosphorylation
0.35	GO:0007154	cell communication
0.34	GO:0009405	pathogenesis

0.73	GO:0008081	phosphoric diester hydrolase activity
0.40	GO:0016158	3-phytase activity
0.36	GO:0005509	calcium ion binding
0.33	GO:0003993	acid phosphatase activity

0.33	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.73

EC:3.1.4

GO:0008081

tr|T1FTT7|T1FTT7_HELRO
Uncharacterized protein
Search

0.37	GO:0008017	microtubule binding
0.36	GO:0005509	calcium ion binding

0.69

GO:0005856

cytoskeleton

tr|T1FTT8|T1FTT8_HELRO
Uncharacterized protein
Search

0.80	GO:0045010	actin nucleation
0.69	GO:0016192	vesicle-mediated transport
0.51	GO:0051295	establishment of meiotic spindle localization
0.43	GO:0040038	polar body extrusion after meiotic divisions
0.42	GO:0070649	formin-nucleated actin cable assembly
0.42	GO:0036089	cleavage furrow formation
0.38	GO:0046907	intracellular transport
0.37	GO:0016310	phosphorylation
0.33	GO:0015031	protein transport
0.33	GO:0045454	cell redox homeostasis

0.74	GO:0003779	actin binding
0.37	GO:0016301	kinase activity
0.34	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.33	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.33	GO:0046872	metal ion binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.42	GO:0005654	nucleoplasm
0.41	GO:0032154	cleavage furrow
0.41	GO:0005829	cytosol
0.39	GO:0030659	cytoplasmic vesicle membrane
0.39	GO:0005938	cell cortex
0.35	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0005856	cytoskeleton
0.33	GO:0005886	plasma membrane

0.33

EC:1.2.1

GO:0016620

tr|T1FTT9|T1FTT9_HELRO
Uncharacterized protein
Search

tr|T1FTU0|T1FTU0_HELRO
Uncharacterized protein
Search

0.76	GO:0016579	protein deubiquitination
0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.51	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.49	GO:0045751	negative regulation of Toll signaling pathway
0.48	GO:1900425	negative regulation of defense response to bacterium
0.47	GO:0002784	regulation of antimicrobial peptide production
0.46	GO:0035220	wing disc development
0.46	GO:0030307	positive regulation of cell growth
0.45	GO:0060968	regulation of gene silencing
0.45	GO:0043687	post-translational protein modification

0.77	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.47	GO:0004197	cysteine-type endopeptidase activity
0.35	GO:0008536	Ran GTPase binding
0.33	GO:0004601	peroxidase activity
0.33	GO:0003677	DNA binding
0.32	GO:0020037	heme binding

0.40	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.77	EC:3.4.19.12	GO:0036459
0.33	KEGG:R03532	GO:0004601

tr|T1FTU1|T1FTU1_HELRO
Uncharacterized protein
Search

tr|T1FTU2|T1FTU2_HELRO
Uncharacterized protein
Search

0.49	GO:0007275	multicellular organism development
0.47	GO:0007219	Notch signaling pathway
0.45	GO:0007155	cell adhesion
0.44	GO:0030154	cell differentiation
0.42	GO:0050793	regulation of developmental process
0.38	GO:0009653	anatomical structure morphogenesis
0.38	GO:0009888	tissue development
0.37	GO:0106036	assembly of apicomedial cortex actomyosin
0.37	GO:0051241	negative regulation of multicellular organismal process
0.37	GO:0006030	chitin metabolic process

0.70	GO:0005509	calcium ion binding
0.37	GO:0008061	chitin binding
0.36	GO:0004872	receptor activity
0.36	GO:0005080	protein kinase C binding
0.36	GO:0030507	spectrin binding
0.33	GO:0004252	serine-type endopeptidase activity
0.33	GO:0005198	structural molecule activity
0.32	GO:0003677	DNA binding

0.38	GO:0033166	hyaline layer
0.38	GO:0005886	plasma membrane
0.37	GO:0005911	cell-cell junction
0.36	GO:0016028	rhabdomere
0.36	GO:0044420	extracellular matrix component
0.36	GO:0031410	cytoplasmic vesicle
0.36	GO:0005615	extracellular space
0.35	GO:0005912	adherens junction
0.35	GO:0045177	apical part of cell
0.35	GO:0005819	spindle

0.33

GO:0004252

tr|T1FTU3|T1FTU3_HELRO
Uncharacterized protein
Search

0.59	GO:0006396	RNA processing
0.37	GO:0006914	autophagy
0.35	GO:0016071	mRNA metabolic process

0.56	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.45	GO:0005654	nucleoplasm
0.36	GO:0005681	spliceosomal complex
0.30	GO:0031224	intrinsic component of membrane

tr|T1FTU4|T1FTU4_HELRO
Uncharacterized protein
Search

0.63	GO:0032259	methylation
0.48	GO:0030187	melatonin biosynthetic process
0.39	GO:1903506	regulation of nucleic acid-templated transcription
0.39	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.39	GO:0010468	regulation of gene expression
0.36	GO:0009234	menaquinone biosynthetic process
0.36	GO:0006744	ubiquinone biosynthetic process
0.35	GO:0009060	aerobic respiration

0.73	GO:0008171	O-methyltransferase activity
0.44	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity
0.43	GO:0042803	protein homodimerization activity
0.40	GO:0003700	DNA binding transcription factor activity
0.37	GO:0102005	2-octaprenyl-6-methoxy-1,4-benzoquinone methylase activity
0.37	GO:0102955	S-adenosylmethionine:2-demethylmenaquinol-7 methyltransferase activity
0.37	GO:0008169	C-methyltransferase activity

0.73

GO:0008171

tr|T1FTU5|T1FTU5_HELRO
Uncharacterized protein
Search

tr|T1FTU6|T1FTU6_HELRO
Uncharacterized protein
Search

EIF2A

0.72	Eukaryotic translation initiation factor 2A

0.70	GO:0006413	translational initiation
0.63	GO:0006417	regulation of translation
0.49	GO:0032933	SREBP signaling pathway
0.47	GO:0042255	ribosome assembly
0.46	GO:0009967	positive regulation of signal transduction
0.41	GO:0006468	protein phosphorylation
0.39	GO:1990928	response to amino acid starvation

0.71	GO:0003743	translation initiation factor activity
0.49	GO:0043022	ribosome binding
0.49	GO:0045296	cadherin binding
0.47	GO:0000049	tRNA binding
0.45	GO:0003729	mRNA binding

0.52	GO:0005850	eukaryotic translation initiation factor 2 complex
0.46	GO:0022627	cytosolic small ribosomal subunit
0.38	GO:0070449	elongin complex
0.36	GO:0072562	blood microparticle
0.30	GO:0016020	membrane

tr|T1FTU7|T1FTU7_HELRO
Uncharacterized protein
Search

0.47	GO:0035335	peptidyl-tyrosine dephosphorylation
0.43	GO:0060255	regulation of macromolecule metabolic process
0.42	GO:0031323	regulation of cellular metabolic process
0.42	GO:0051171	regulation of nitrogen compound metabolic process
0.42	GO:0080090	regulation of primary metabolic process
0.41	GO:0009889	regulation of biosynthetic process
0.40	GO:0043044	ATP-dependent chromatin remodeling
0.40	GO:0051347	positive regulation of transferase activity
0.38	GO:0009893	positive regulation of metabolic process
0.38	GO:0006468	protein phosphorylation

0.48	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.47	GO:0004725	protein tyrosine phosphatase activity
0.44	GO:0003676	nucleic acid binding
0.42	GO:0030296	protein tyrosine kinase activator activity
0.41	GO:0003700	DNA binding transcription factor activity
0.41	GO:0050825	ice binding
0.40	GO:0017137	Rab GTPase binding
0.39	GO:0008270	zinc ion binding
0.39	GO:0045182	translation regulator activity
0.38	GO:0046982	protein heterodimerization activity

0.40	GO:0005912	adherens junction
0.40	GO:0016602	CCAAT-binding factor complex
0.30	GO:0016020	membrane

0.48

EC:3.1.3

GO:0008138

tr|T1FTU8|T1FTU8_HELRO
Uncharacterized protein
Search

0.43	GO:0048738	cardiac muscle tissue development
0.43	GO:0007519	skeletal muscle tissue development
0.43	GO:0032233	positive regulation of actin filament bundle assembly
0.33	GO:0032774	RNA biosynthetic process

0.50	GO:0046872	metal ion binding
0.40	GO:0003779	actin binding
0.35	GO:0031005	filamin binding
0.35	GO:0051393	alpha-actinin binding
0.33	GO:0003899	DNA-directed 5'-3' RNA polymerase activity

0.45	GO:0016607	nuclear speck
0.44	GO:0030054	cell junction
0.42	GO:0030018	Z disc
0.42	GO:0005829	cytosol
0.40	GO:0015629	actin cytoskeleton
0.33	GO:0044430	cytoskeletal part
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0003899

tr|T1FTU9|T1FTU9_HELRO
Uncharacterized protein
Search

tr|T1FTV0|T1FTV0_HELRO
Uncharacterized protein
Search

0.63	GO:0006468	protein phosphorylation
0.46	GO:0042149	cellular response to glucose starvation
0.44	GO:0043066	negative regulation of apoptotic process
0.42	GO:0030036	actin cytoskeleton organization
0.37	GO:0035556	intracellular signal transduction
0.35	GO:0055002	striated muscle cell development
0.35	GO:0010927	cellular component assembly involved in morphogenesis
0.35	GO:0006915	apoptotic process
0.35	GO:0097435	supramolecular fiber organization
0.34	GO:0070925	organelle assembly

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0000287	magnesium ion binding
0.36	GO:0008307	structural constituent of muscle
0.33	GO:0005515	protein binding
0.32	GO:0016787	hydrolase activity

0.43	GO:0016607	nuclear speck
0.36	GO:0031430	M band
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016787

tr|T1FTV1|T1FTV1_HELRO
Uncharacterized protein
Search

0.46	GO:0006413	translational initiation
0.42	GO:0035114	imaginal disc-derived appendage morphogenesis
0.41	GO:0035295	tube development
0.41	GO:0007009	plasma membrane organization
0.41	GO:0048731	system development
0.41	GO:0060429	epithelium development
0.39	GO:0060255	regulation of macromolecule metabolic process
0.39	GO:0031323	regulation of cellular metabolic process
0.39	GO:0051171	regulation of nitrogen compound metabolic process
0.39	GO:0080090	regulation of primary metabolic process

0.46	GO:0003743	translation initiation factor activity
0.40	GO:0003700	DNA binding transcription factor activity
0.40	GO:0005515	protein binding
0.40	GO:0043565	sequence-specific DNA binding
0.39	GO:0004491	methylmalonate-semialdehyde dehydrogenase (acylating) activity
0.38	GO:0050825	ice binding
0.38	GO:0046872	metal ion binding
0.38	GO:0001012	RNA polymerase II regulatory region DNA binding
0.37	GO:0005254	chloride channel activity
0.37	GO:0003690	double-stranded DNA binding

0.41	GO:0005634	nucleus
0.38	GO:0034707	chloride channel complex
0.37	GO:0048786	presynaptic active zone
0.35	GO:0044446	intracellular organelle part
0.35	GO:0098805	whole membrane
0.35	GO:0098588	bounding membrane of organelle
0.35	GO:0005700	polytene chromosome
0.35	GO:0045179	apical cortex
0.35	GO:0033180	proton-transporting V-type ATPase, V1 domain
0.35	GO:0070013	intracellular organelle lumen

0.39

EC:1.2.1.27

GO:0004491

tr|T1FTV2|T1FTV2_HELRO
Uncharacterized protein
Search

0.11	Phosphorylase b kinase regulatory subunit

0.75	GO:0005977	glycogen metabolic process
0.50	GO:0016310	phosphorylation
0.33	GO:0006464	cellular protein modification process

0.79	GO:0005516	calmodulin binding
0.52	GO:0016301	kinase activity
0.33	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.33	GO:0140096	catalytic activity, acting on a protein

0.55	GO:0005886	plasma membrane
0.36	GO:0005964	phosphorylase kinase complex
0.35	GO:0005634	nucleus
0.30	GO:0044425	membrane part

0.33

GO:0016773

tr|T1FTV3|T1FTV3_HELRO
Uncharacterized protein
Search

0.44	GO:0035023	regulation of Rho protein signal transduction
0.43	GO:0006030	chitin metabolic process
0.42	GO:0042594	response to starvation
0.40	GO:0065009	regulation of molecular function
0.40	GO:0098507	polynucleotide 5' dephosphorylation
0.39	GO:0051716	cellular response to stimulus
0.39	GO:0007605	sensory perception of sound
0.39	GO:0036211	protein modification process
0.38	GO:0007018	microtubule-based movement
0.38	GO:0044260	cellular macromolecule metabolic process

0.47	GO:0008270	zinc ion binding
0.44	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.43	GO:0008061	chitin binding
0.42	GO:0003676	nucleic acid binding
0.40	GO:0004674	protein serine/threonine kinase activity
0.40	GO:0004651	polynucleotide 5'-phosphatase activity
0.39	GO:0001085	RNA polymerase II transcription factor binding
0.39	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.38	GO:0051087	chaperone binding
0.38	GO:0003777	microtubule motor activity

0.44	GO:0005634	nucleus
0.40	GO:0044446	intracellular organelle part
0.40	GO:0032991	macromolecular complex
0.40	GO:0005576	extracellular region
0.39	GO:0031974	membrane-enclosed lumen
0.38	GO:0015629	actin cytoskeleton
0.36	GO:0012505	endomembrane system
0.36	GO:0005694	chromosome
0.35	GO:0031975	envelope
0.30	GO:0016020	membrane

0.40

GO:0004674

tr|T1FTV4|T1FTV4_HELRO
Uncharacterized protein
Search

tr|T1FTV5|T1FTV5_HELRO
Uncharacterized protein
Search

0.50	GO:0003676	nucleic acid binding
0.34	GO:0046872	metal ion binding

0.30

GO:0044425

membrane part

tr|T1FTV6|T1FTV6_HELRO
Uncharacterized protein
Search

tr|T1FTV7|T1FTV7_HELRO
Uncharacterized protein
Search

tr|T1FTV8|T1FTV8_HELRO
Uncharacterized protein
Search

tr|T1FTV9|T1FTV9_HELRO
Sulfhydryl oxidase
Search

0.29	Sulfhydryl oxidase

0.63	GO:0045454	cell redox homeostasis
0.51	GO:0055114	oxidation-reduction process
0.42	GO:0034975	protein folding in endoplasmic reticulum
0.40	GO:0034551	mitochondrial respiratory chain complex III assembly
0.38	GO:0016567	protein ubiquitination
0.37	GO:0030001	metal ion transport
0.35	GO:0055085	transmembrane transport
0.34	GO:0032504	multicellular organism reproduction
0.34	GO:0006836	neurotransmitter transport
0.34	GO:0034453	microtubule anchoring

0.81	GO:0016972	thiol oxidase activity
0.44	GO:0003756	protein disulfide isomerase activity
0.38	GO:0004842	ubiquitin-protein transferase activity
0.38	GO:0046873	metal ion transmembrane transporter activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005326	neurotransmitter transporter activity
0.34	GO:0015294	solute:cation symporter activity
0.33	GO:0004826	phenylalanine-tRNA ligase activity

0.44	GO:0030173	integral component of Golgi membrane
0.42	GO:0005615	extracellular space
0.40	GO:0005654	nucleoplasm
0.40	GO:0000813	ESCRT I complex
0.36	GO:0005739	mitochondrion
0.34	GO:0031965	nuclear membrane
0.33	GO:0005960	glycine cleavage complex
0.33	GO:0005813	centrosome
0.32	GO:0019866	organelle inner membrane
0.32	GO:0005886	plasma membrane

0.81	EC:1.8.3.2	GO:0016972
0.38	KEGG:R03876	GO:0004842

tr|T1FTW0|T1FTW0_HELRO
Uncharacterized protein
Search

CHD2

0.75	Down syndrome cell adhesion molecule

0.53	GO:0060218	hematopoietic stem cell differentiation
0.50	GO:0007517	muscle organ development
0.43	GO:0006974	cellular response to DNA damage stimulus
0.36	GO:0016569	covalent chromatin modification
0.35	GO:0043009	chordate embryonic development
0.35	GO:0043923	positive regulation by host of viral transcription
0.34	GO:0040011	locomotion
0.34	GO:0006338	chromatin remodeling
0.33	GO:0006357	regulation of transcription by RNA polymerase II
0.33	GO:0032392	DNA geometric change

0.56	GO:0004386	helicase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0001046	core promoter sequence-specific DNA binding
0.50	GO:0042393	histone binding
0.35	GO:0003723	RNA binding
0.34	GO:0140034	methylation-dependent protein binding
0.33	GO:0008094	DNA-dependent ATPase activity
0.33	GO:0140097	catalytic activity, acting on DNA

0.61	GO:0005634	nucleus
0.44	GO:0031974	membrane-enclosed lumen
0.41	GO:0043232	intracellular non-membrane-bounded organelle
0.41	GO:0044446	intracellular organelle part
0.38	GO:0070062	extracellular exosome
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1FTW1|T1FTW1_HELRO
Uncharacterized protein
Search

0.66	GO:0071896	protein localization to adherens junction
0.65	GO:0001921	positive regulation of receptor recycling
0.64	GO:0060561	apoptotic process involved in morphogenesis
0.64	GO:0035089	establishment of apical/basal cell polarity
0.63	GO:0050918	positive chemotaxis
0.62	GO:0001843	neural tube closure
0.62	GO:0090630	activation of GTPase activity
0.59	GO:0008283	cell proliferation
0.58	GO:0043065	positive regulation of apoptotic process
0.58	GO:0045930	negative regulation of mitotic cell cycle

0.60

GO:0045296

cadherin binding

0.67	GO:0034750	Scrib-APC-beta-catenin complex
0.63	GO:0042734	presynaptic membrane
0.61	GO:0005913	cell-cell adherens junction
0.59	GO:0031252	cell leading edge
0.58	GO:0045211	postsynaptic membrane
0.55	GO:0035748	myelin sheath abaxonal region
0.53	GO:0005654	nucleoplasm
0.53	GO:0044291	cell-cell contact zone
0.52	GO:0016323	basolateral plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1FTW2|T1FTW2_HELRO
Uncharacterized protein
Search

tr|T1FTW3|T1FTW3_HELRO
Uncharacterized protein
Search

0.39	GO:0036211	protein modification process
0.38	GO:0051276	chromosome organization
0.38	GO:0042545	cell wall modification
0.38	GO:0044267	cellular protein metabolic process
0.37	GO:0009057	macromolecule catabolic process
0.37	GO:1901565	organonitrogen compound catabolic process
0.37	GO:1901072	glucosamine-containing compound catabolic process
0.37	GO:0044248	cellular catabolic process
0.37	GO:0000724	double-strand break repair via homologous recombination
0.36	GO:0098732	macromolecule deacylation

0.44	GO:0046872	metal ion binding
0.38	GO:0030248	cellulose binding
0.38	GO:0045330	aspartyl esterase activity
0.38	GO:0030599	pectinesterase activity
0.37	GO:0061630	ubiquitin protein ligase activity
0.37	GO:0043140	ATP-dependent 3'-5' DNA helicase activity
0.37	GO:0003676	nucleic acid binding
0.37	GO:0004402	histone acetyltransferase activity
0.37	GO:0004568	chitinase activity
0.37	GO:0009378	four-way junction helicase activity

0.41	GO:0005634	nucleus
0.37	GO:1990234	transferase complex
0.37	GO:0031974	membrane-enclosed lumen
0.37	GO:0005618	cell wall
0.36	GO:0005667	transcription factor complex
0.36	GO:0005576	extracellular region
0.35	GO:0044446	intracellular organelle part
0.35	GO:0005694	chromosome
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.38

EC:3.1.1.11

GO:0030599

tr|T1FTW4|T1FTW4_HELRO
Uncharacterized protein
Search

0.44	Heterogeneous nuclear ribonucleoprotein K

0.45	GO:0006357	regulation of transcription by RNA polymerase II
0.42	GO:0006396	RNA processing
0.42	GO:0032501	multicellular organismal process
0.41	GO:0005975	carbohydrate metabolic process
0.40	GO:0051716	cellular response to stimulus
0.39	GO:0048856	anatomical structure development
0.39	GO:0006950	response to stress
0.37	GO:0023052	signaling
0.37	GO:0007154	cell communication
0.35	GO:0015074	DNA integration

0.59	GO:0003723	RNA binding
0.43	GO:0016757	transferase activity, transferring glycosyl groups
0.39	GO:0003677	DNA binding
0.39	GO:0004888	transmembrane signaling receptor activity
0.34	GO:0005515	protein binding
0.33	GO:0004386	helicase activity
0.33	GO:0004540	ribonuclease activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.47	GO:0019013	viral nucleocapsid
0.43	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0005634	nucleus
0.32	GO:0044446	intracellular organelle part
0.32	GO:0031974	membrane-enclosed lumen
0.31	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.43

GO:0016757

tr|T1FTW5|T1FTW5_HELRO
Uncharacterized protein
Search

0.48	Heterogeneous nuclear ribonucleoprotein K

0.57	GO:0006357	regulation of transcription by RNA polymerase II
0.52	GO:0006396	RNA processing
0.41	GO:1902165	regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
0.41	GO:0045716	positive regulation of low-density lipoprotein particle receptor biosynthetic process
0.41	GO:0048025	negative regulation of mRNA splicing, via spliceosome
0.40	GO:0010988	regulation of low-density lipoprotein particle clearance
0.40	GO:0048260	positive regulation of receptor-mediated endocytosis
0.39	GO:0032368	regulation of lipid transport
0.39	GO:0005975	carbohydrate metabolic process
0.38	GO:0010628	positive regulation of gene expression

0.58	GO:0003723	RNA binding
0.47	GO:0003677	DNA binding
0.40	GO:0016757	transferase activity, transferring glycosyl groups
0.39	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.39	GO:0045296	cadherin binding
0.38	GO:0019904	protein domain specific binding
0.38	GO:0001067	regulatory region nucleic acid binding
0.37	GO:0042802	identical protein binding
0.33	GO:0005521	lamin binding
0.33	GO:0051117	ATPase binding

0.51	GO:0019013	viral nucleocapsid
0.46	GO:0030529	intracellular ribonucleoprotein complex
0.39	GO:0005634	nucleus
0.37	GO:0000785	chromatin
0.37	GO:0070013	intracellular organelle lumen
0.36	GO:0002102	podosome
0.35	GO:1902494	catalytic complex
0.35	GO:0030054	cell junction
0.34	GO:0042995	cell projection
0.33	GO:0014069	postsynaptic density

0.40

GO:0016757

tr|T1FTW6|T1FTW6_HELRO
Uncharacterized protein
Search

0.53	ATP-binding cassette sub-family B member 6, mitochondrial

0.55	GO:0055085	transmembrane transport
0.46	GO:0043588	skin development
0.44	GO:0007420	brain development
0.44	GO:0015886	heme transport
0.42	GO:0006779	porphyrin-containing compound biosynthetic process
0.39	GO:0097325	melanocyte proliferation
0.39	GO:0061072	iris morphogenesis
0.35	GO:0042908	xenobiotic transport
0.35	GO:0006879	cellular iron ion homeostasis
0.34	GO:0015893	drug transport

0.66	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0015232	heme transporter activity
0.43	GO:0015562	efflux transmembrane transporter activity
0.40	GO:0020037	heme binding
0.35	GO:0042910	xenobiotic transmembrane transporter activity
0.34	GO:0015238	drug transmembrane transporter activity

0.46	GO:0031307	integral component of mitochondrial outer membrane
0.43	GO:0005768	endosome
0.43	GO:0005794	Golgi apparatus
0.42	GO:0005654	nucleoplasm
0.42	GO:0005829	cytosol
0.42	GO:0005783	endoplasmic reticulum
0.38	GO:0005886	plasma membrane
0.37	GO:0070062	extracellular exosome
0.36	GO:0044433	cytoplasmic vesicle part
0.36	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network

tr|T1FTW7|T1FTW7_HELRO
Uncharacterized protein
Search

tr|T1FTW8|T1FTW8_HELRO
Uncharacterized protein
Search

tr|T1FTW9|T1FTW9_HELRO
Uncharacterized protein
Search

tr|T1FTX0|T1FTX0_HELRO
Uncharacterized protein
Search

tr|T1FTX1|T1FTX1_HELRO
Uncharacterized protein
Search

tr|T1FTX2|T1FTX2_HELRO
Uncharacterized protein
Search

tr|T1FTX3|T1FTX3_HELRO
Uncharacterized protein
Search

tr|T1FTX4|T1FTX4_HELRO
Uncharacterized protein
Search

0.59	Cholinergic receptor nicotinic alpha 7 subunit

0.77	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.46	GO:0007271	synaptic transmission, cholinergic
0.45	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound
0.43	GO:0042472	inner ear morphogenesis
0.43	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.40	GO:0035094	response to nicotine
0.39	GO:0001988	positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure
0.39	GO:1905920	positive regulation of CoA-transferase activity
0.39	GO:0060112	generation of ovulation cycle rhythm

0.80	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0004888	transmembrane signaling receptor activity
0.39	GO:0005509	calcium ion binding
0.35	GO:0017056	structural constituent of nuclear pore
0.35	GO:0005262	calcium channel activity
0.33	GO:0022850	serotonin-gated cation-selective channel activity
0.33	GO:0005102	receptor binding

0.77	GO:0045211	postsynaptic membrane
0.72	GO:0030054	cell junction
0.51	GO:0043204	perikaryon
0.50	GO:0030424	axon
0.48	GO:0030425	dendrite
0.38	GO:0005892	acetylcholine-gated channel complex
0.37	GO:0032589	neuron projection membrane
0.37	GO:0005737	cytoplasm
0.37	GO:0009897	external side of plasma membrane
0.37	GO:0016324	apical plasma membrane

tr|T1FTX5|T1FTX5_HELRO
Uncharacterized protein
Search

tr|T1FTX6|T1FTX6_HELRO
Uncharacterized protein
Search

0.59	GO:1901622	positive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
0.54	GO:1905515	non-motile cilium assembly
0.50	GO:0006429	leucyl-tRNA aminoacylation
0.48	GO:0106074	aminoacyl-tRNA metabolism involved in translational fidelity
0.45	GO:0070870	heterochromatin maintenance involved in chromatin silencing
0.45	GO:0070869	heterochromatin assembly involved in chromatin silencing
0.44	GO:0000729	DNA double-strand break processing
0.44	GO:0042766	nucleosome mobilization
0.44	GO:0016584	nucleosome positioning
0.43	GO:0000183	chromatin silencing at rDNA

0.50	GO:0004823	leucine-tRNA ligase activity
0.48	GO:0002161	aminoacyl-tRNA editing activity
0.43	GO:0032559	adenyl ribonucleotide binding
0.43	GO:0008144	drug binding
0.43	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.42	GO:0004722	protein serine/threonine phosphatase activity
0.41	GO:0003682	chromatin binding
0.41	GO:0042802	identical protein binding
0.40	GO:0008094	DNA-dependent ATPase activity

0.49	GO:0005730	nucleolus
0.49	GO:0005794	Golgi apparatus
0.48	GO:0005654	nucleoplasm
0.47	GO:0005829	cytosol
0.44	GO:0031934	mating-type region heterochromatin
0.42	GO:0000781	chromosome, telomeric region
0.41	GO:0000775	chromosome, centromeric region
0.30	GO:0031224	intrinsic component of membrane

0.50	EC:6.1.1.4	GO:0004823
0.50	KEGG:R03657	GO:0004823

tr|T1FTX7|T1FTX7_HELRO
Uncharacterized protein
Search

0.64	GO:0016192	vesicle-mediated transport
0.64	GO:0046907	intracellular transport
0.63	GO:0034613	cellular protein localization
0.60	GO:0015031	protein transport
0.58	GO:0098657	import into cell
0.42	GO:0016050	vesicle organization
0.39	GO:0007638	mechanosensory behavior
0.39	GO:0035418	protein localization to synapse
0.39	GO:0090382	phagosome maturation
0.39	GO:0097194	execution phase of apoptosis

0.76	GO:0035091	phosphatidylinositol binding
0.39	GO:0043621	protein self-association
0.32	GO:0000996	promoter selection factor activity
0.32	GO:0003700	DNA binding transcription factor activity
0.31	GO:0003677	DNA binding
0.31	GO:0008233	peptidase activity

0.75	GO:0030904	retromer complex
0.53	GO:0005829	cytosol
0.41	GO:0005768	endosome
0.40	GO:0019898	extrinsic component of membrane
0.40	GO:0044433	cytoplasmic vesicle part
0.39	GO:0032009	early phagosome
0.39	GO:0098805	whole membrane
0.39	GO:0098588	bounding membrane of organelle
0.30	GO:0031224	intrinsic component of membrane

0.31

GO:0008233

tr|T1FTX8|T1FTX8_HELRO
Uncharacterized protein
Search

tr|T1FTX9|T1FTX9_HELRO
Uncharacterized protein
Search

0.45	universal stress protein YxiE

0.61

GO:0006950

response to stress

0.35

GO:0005737

cytoplasm

tr|T1FTY0|T1FTY0_HELRO
Uncharacterized protein
Search

0.63	GO:0006468	protein phosphorylation
0.39	GO:2000286	receptor internalization involved in canonical Wnt signaling pathway
0.39	GO:2000370	positive regulation of clathrin-dependent endocytosis
0.39	GO:0002092	positive regulation of receptor internalization
0.38	GO:0008333	endosome to lysosome transport
0.38	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.38	GO:0032504	multicellular organism reproduction
0.34	GO:0006511	ubiquitin-dependent protein catabolic process

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0005102	receptor binding
0.35	GO:0031625	ubiquitin protein ligase binding

0.35	GO:0030136	clathrin-coated vesicle
0.35	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0010008	endosome membrane
0.34	GO:0005794	Golgi apparatus
0.30	GO:0016021	integral component of membrane

tr|T1FTY1|T1FTY1_HELRO
Uncharacterized protein
Search

0.83	GO:0045292	mRNA cis splicing, via spliceosome
0.76	GO:0051028	mRNA transport
0.49	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.48	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.47	GO:0031442	positive regulation of mRNA 3'-end processing
0.47	GO:1905216	positive regulation of RNA binding
0.46	GO:0006405	RNA export from nucleus
0.46	GO:0031053	primary miRNA processing
0.46	GO:0048026	positive regulation of mRNA splicing, via spliceosome
0.45	GO:0098789	pre-mRNA cleavage required for polyadenylation

0.83	GO:0000339	RNA cap binding
0.42	GO:0003729	mRNA binding
0.32	GO:0005509	calcium ion binding

0.84	GO:0005846	nuclear cap binding complex
0.49	GO:0005845	mRNA cap binding complex
0.41	GO:0005634	nucleus
0.41	GO:0030529	intracellular ribonucleoprotein complex
0.40	GO:0005829	cytosol
0.40	GO:0031974	membrane-enclosed lumen
0.38	GO:0005739	mitochondrion
0.38	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

tr|T1FTY2|T1FTY2_HELRO
Uncharacterized protein
Search

0.11

Gremlin

0.65	GO:0010469	regulation of receptor activity
0.63	GO:0048263	determination of dorsal identity
0.62	GO:0038098	sequestering of BMP from receptor via BMP binding
0.59	GO:1900120	regulation of receptor binding
0.58	GO:0010172	embryonic body morphogenesis
0.54	GO:0019221	cytokine-mediated signaling pathway
0.47	GO:1901213	regulation of transcription from RNA polymerase II promoter involved in heart development
0.44	GO:0007167	enzyme linked receptor protein signaling pathway
0.44	GO:0090291	negative regulation of osteoclast proliferation
0.43	GO:0048729	tissue morphogenesis

0.66	GO:0005125	cytokine activity
0.62	GO:0036122	BMP binding
0.56	GO:0008201	heparin binding
0.54	GO:0042803	protein homodimerization activity
0.43	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity
0.43	GO:0043184	vascular endothelial growth factor receptor 2 binding

0.63	GO:0005615	extracellular space
0.39	GO:0009986	cell surface
0.30	GO:0016020	membrane

tr|T1FTY3|T1FTY3_HELRO
Uncharacterized protein
Search

0.45	GO:0006289	nucleotide-excision repair
0.44	GO:0032392	DNA geometric change
0.39	GO:1903506	regulation of nucleic acid-templated transcription
0.39	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.39	GO:0010468	regulation of gene expression
0.39	GO:0016925	protein sumoylation
0.39	GO:0006508	proteolysis
0.38	GO:0071805	potassium ion transmembrane transport
0.36	GO:0032012	regulation of ARF protein signal transduction
0.35	GO:0035435	phosphate ion transmembrane transport

0.45	GO:0004003	ATP-dependent DNA helicase activity
0.44	GO:0005525	GTP binding
0.41	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.40	GO:0003677	DNA binding
0.39	GO:0032559	adenyl ribonucleotide binding
0.39	GO:0003700	DNA binding transcription factor activity
0.39	GO:0008144	drug binding
0.39	GO:0019789	SUMO transferase activity
0.38	GO:0005249	voltage-gated potassium channel activity
0.37	GO:0016874	ligase activity

0.42	GO:0005634	nucleus
0.38	GO:0008076	voltage-gated potassium channel complex
0.37	GO:0020011	apicoplast
0.36	GO:0070701	mucus layer
0.35	GO:0005829	cytosol

0.37

GO:0016874

tr|T1FTY4|T1FTY4_HELRO
Uncharacterized protein
Search

tr|T1FTY5|T1FTY5_HELRO
Uncharacterized protein
Search

0.48	GO:0005975	carbohydrate metabolic process
0.42	GO:0009057	macromolecule catabolic process
0.39	GO:0044248	cellular catabolic process
0.39	GO:0010951	negative regulation of endopeptidase activity
0.36	GO:0044260	cellular macromolecule metabolic process
0.35	GO:0071554	cell wall organization or biogenesis
0.34	GO:0006508	proteolysis
0.34	GO:2000142	regulation of DNA-templated transcription, initiation
0.33	GO:0035023	regulation of Rho protein signal transduction
0.33	GO:0007010	cytoskeleton organization

0.52	GO:0030246	carbohydrate binding
0.52	GO:0016746	transferase activity, transferring acyl groups
0.51	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.48	GO:0008061	chitin binding
0.40	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.39	GO:0004867	serine-type endopeptidase inhibitor activity
0.35	GO:0005509	calcium ion binding
0.35	GO:0001871	pattern binding
0.34	GO:0140096	catalytic activity, acting on a protein
0.34	GO:0000996	promoter selection factor activity

0.41	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.52

EC:2.3

GO:0016746

tr|T1FTY6|T1FTY6_HELRO
Uncharacterized protein
Search

0.54	GO:0000413	protein peptidyl-prolyl isomerization
0.50	GO:0006457	protein folding
0.40	GO:0043484	regulation of RNA splicing
0.37	GO:0051716	cellular response to stimulus
0.37	GO:0010501	RNA secondary structure unwinding
0.36	GO:0045892	negative regulation of transcription, DNA-templated
0.36	GO:0006950	response to stress
0.36	GO:0006259	DNA metabolic process
0.35	GO:0000398	mRNA splicing, via spliceosome
0.35	GO:0006468	protein phosphorylation

0.54	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.48	GO:0003723	RNA binding
0.40	GO:0004386	helicase activity
0.39	GO:0046872	metal ion binding
0.38	GO:0032559	adenyl ribonucleotide binding
0.38	GO:0008144	drug binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0004674	protein serine/threonine kinase activity
0.36	GO:0008186	RNA-dependent ATPase activity
0.35	GO:0004842	ubiquitin-protein transferase activity

0.42	GO:0044428	nuclear part
0.41	GO:0031974	membrane-enclosed lumen
0.41	GO:0005829	cytosol
0.39	GO:0005739	mitochondrion
0.38	GO:0005773	vacuole
0.37	GO:0005886	plasma membrane
0.34	GO:1902494	catalytic complex
0.34	GO:0030529	intracellular ribonucleoprotein complex
0.34	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

0.54	EC:5.2.1.8	GO:0003755
0.35	KEGG:R03876	GO:0004842

tr|T1FTY7|T1FTY7_HELRO
Uncharacterized protein
Search

0.75	GO:0010951	negative regulation of endopeptidase activity
0.40	GO:0050829	defense response to Gram-negative bacterium
0.38	GO:0032101	regulation of response to external stimulus
0.38	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.38	GO:1903035	negative regulation of response to wounding
0.38	GO:0061041	regulation of wound healing
0.37	GO:0006030	chitin metabolic process
0.37	GO:0072675	osteoclast fusion
0.36	GO:0010839	negative regulation of keratinocyte proliferation
0.36	GO:0045616	regulation of keratinocyte differentiation

0.75	GO:0004866	endopeptidase inhibitor activity
0.39	GO:0019955	cytokine binding
0.39	GO:0019838	growth factor binding
0.37	GO:0008061	chitin binding
0.35	GO:0048306	calcium-dependent protein binding
0.35	GO:0002020	protease binding
0.34	GO:0005102	receptor binding
0.34	GO:0005509	calcium ion binding
0.33	GO:0008233	peptidase activity

0.73	GO:0005615	extracellular space
0.35	GO:0009986	cell surface
0.33	GO:1903561	extracellular vesicle
0.30	GO:0016020	membrane

0.33

GO:0008233

tr|T1FTY8|T1FTY8_HELRO
Uncharacterized protein
Search

tr|T1FTY9|T1FTY9_HELRO
Uncharacterized protein
Search

tr|T1FTZ0|T1FTZ0_HELRO
Uncharacterized protein
Search

0.77	GO:0035023	regulation of Rho protein signal transduction
0.66	GO:0065009	regulation of molecular function
0.49	GO:0035556	intracellular signal transduction
0.47	GO:0006468	protein phosphorylation

0.78	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.50	GO:0004674	protein serine/threonine kinase activity
0.42	GO:0032559	adenyl ribonucleotide binding
0.41	GO:0008144	drug binding
0.41	GO:0035639	purine ribonucleoside triphosphate binding

0.44	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.50

GO:0004674

tr|T1FTZ1|T1FTZ1_HELRO
Uncharacterized protein
Search

0.50	GO:0010466	negative regulation of peptidase activity
0.49	GO:0052548	regulation of endopeptidase activity
0.41	GO:0006508	proteolysis
0.34	GO:0006030	chitin metabolic process
0.34	GO:0002119	nematode larval development
0.33	GO:0030198	extracellular matrix organization
0.33	GO:0009792	embryo development ending in birth or egg hatching
0.33	GO:0048598	embryonic morphogenesis
0.33	GO:0032504	multicellular organism reproduction
0.33	GO:0000902	cell morphogenesis

0.66	GO:0005509	calcium ion binding
0.51	GO:0004867	serine-type endopeptidase inhibitor activity
0.41	GO:0008233	peptidase activity
0.34	GO:0008061	chitin binding
0.33	GO:0005201	extracellular matrix structural constituent
0.33	GO:0008270	zinc ion binding
0.33	GO:0003700	DNA binding transcription factor activity
0.33	GO:0051539	4 iron, 4 sulfur cluster binding

0.38	GO:0005576	extracellular region
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.41

GO:0008233

tr|T1FTZ2|T1FTZ2_HELRO
Uncharacterized protein
Search

tr|T1FTZ3|T1FTZ3_HELRO
Uncharacterized protein
Search

0.59

GO:0010951

negative regulation of endopeptidase activity

0.61

GO:0004867

serine-type endopeptidase inhibitor activity

0.50	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

tr|T1FTZ4|T1FTZ4_HELRO
Uncharacterized protein
Search

tr|T1FTZ5|T1FTZ5_HELRO
Uncharacterized protein
Search

tr|T1FTZ6|T1FTZ6_HELRO
Uncharacterized protein
Search

0.54	GO:0051284	positive regulation of sequestering of calcium ion
0.54	GO:0050982	detection of mechanical stimulus
0.54	GO:0072059	cortical collecting duct development
0.54	GO:0072055	renal cortex development
0.53	GO:0071464	cellular response to hydrostatic pressure
0.53	GO:0061441	renal artery morphogenesis
0.53	GO:0072208	metanephric smooth muscle tissue development
0.53	GO:0031587	positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
0.53	GO:0072080	nephron tubule development
0.53	GO:0001947	heart looping

0.66	GO:0005509	calcium ion binding
0.53	GO:0048763	calcium-induced calcium release activity
0.53	GO:0043398	HLH domain binding
0.51	GO:0015271	outward rectifier potassium channel activity
0.50	GO:0044325	ion channel binding
0.50	GO:0005248	voltage-gated sodium channel activity
0.49	GO:0051219	phosphoprotein binding
0.49	GO:0051117	ATPase binding
0.49	GO:0042805	actinin binding
0.49	GO:0005245	voltage-gated calcium channel activity

0.52	GO:0016323	basolateral plasma membrane
0.52	GO:0002133	polycystin complex
0.52	GO:0045180	basal cortex
0.51	GO:0071458	integral component of cytoplasmic side of endoplasmic reticulum membrane
0.51	GO:0071556	integral component of lumenal side of endoplasmic reticulum membrane
0.50	GO:0031941	filamentous actin
0.49	GO:0060170	ciliary membrane
0.49	GO:0036064	ciliary basal body
0.49	GO:0030027	lamellipodium
0.48	GO:0072686	mitotic spindle

tr|T1FTZ7|T1FTZ7_HELRO
Uncharacterized protein
Search

tr|T1FTZ8|T1FTZ8_HELRO
Uncharacterized protein
Search

0.11	WD domain, G-beta repeat protein

0.66	GO:0007035	vacuolar acidification
0.64	GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly
0.50	GO:1901546	regulation of synaptic vesicle lumen acidification
0.47	GO:0006928	movement of cell or subcellular component
0.46	GO:0014032	neural crest cell development
0.46	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.46	GO:0030100	regulation of endocytosis
0.44	GO:0007017	microtubule-based process
0.42	GO:0051674	localization of cell
0.41	GO:0040011	locomotion

0.59	GO:0017137	Rab GTPase binding
0.44	GO:0003777	microtubule motor activity
0.39	GO:0032559	adenyl ribonucleotide binding
0.39	GO:0008144	drug binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0004672	protein kinase activity

0.68	GO:0043291	RAVE complex
0.60	GO:0008021	synaptic vesicle
0.46	GO:0030286	dynein complex
0.37	GO:0031931	TORC1 complex
0.36	GO:0031932	TORC2 complex
0.30	GO:0031224	intrinsic component of membrane

tr|T1FTZ9|T1FTZ9_HELRO
Uncharacterized protein
Search

0.81	GO:0032008	positive regulation of TOR signaling
0.45	GO:0034198	cellular response to amino acid starvation
0.42	GO:0010506	regulation of autophagy
0.39	GO:0006914	autophagy
0.32	GO:0009085	lysine biosynthetic process
0.32	GO:0055114	oxidation-reduction process

0.33

GO:0004754

saccharopine dehydrogenase (NAD+, L-lysine-forming) activity

0.46	GO:0005765	lysosomal membrane
0.46	GO:0061700	GATOR2 complex
0.32	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.33	EC:1.5.1.7	GO:0004754
0.33	KEGG:R00715	GO:0004754

tr|T1FU00|T1FU00_HELRO
Uncharacterized protein
Search

0.73	GO:0051726	regulation of cell cycle
0.62	GO:0006950	response to stress

0.61

GO:0005634

nucleus

tr|T1FU01|T1FU01_HELRO
Uncharacterized protein
Search

0.65	GO:0043547	positive regulation of GTPase activity
0.54	GO:0007165	signal transduction
0.38	GO:0007426	tracheal outgrowth, open tracheal system
0.38	GO:0034470	ncRNA processing
0.37	GO:0016072	rRNA metabolic process
0.37	GO:0042254	ribosome biogenesis
0.37	GO:0007476	imaginal disc-derived wing morphogenesis
0.37	GO:0016073	snRNA metabolic process
0.36	GO:0006030	chitin metabolic process
0.35	GO:0006357	regulation of transcription by RNA polymerase II

0.66	GO:0005096	GTPase activator activity
0.42	GO:0008270	zinc ion binding
0.38	GO:0004386	helicase activity
0.37	GO:0097367	carbohydrate derivative binding
0.37	GO:0008144	drug binding
0.36	GO:0030554	adenyl nucleotide binding
0.36	GO:0001104	RNA polymerase II transcription cofactor activity
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0003676	nucleic acid binding
0.35	GO:0004674	protein serine/threonine kinase activity

0.37	GO:0044451	nucleoplasm part
0.36	GO:0055029	nuclear DNA-directed RNA polymerase complex
0.35	GO:0043234	protein complex
0.35	GO:0005576	extracellular region
0.35	GO:0005887	integral component of plasma membrane

0.35

GO:0004674

tr|T1FU02|T1FU02_HELRO
Uncharacterized protein
Search

tr|T1FU03|T1FU03_HELRO
Uncharacterized protein
Search

tr|T1FU04|T1FU04_HELRO
Uncharacterized protein
Search

0.55	GO:0034220	ion transmembrane transport
0.49	GO:0071804	cellular potassium ion transport
0.46	GO:0034765	regulation of ion transmembrane transport
0.43	GO:0019935	cyclic-nucleotide-mediated signaling
0.40	GO:0042391	regulation of membrane potential
0.35	GO:0006468	protein phosphorylation

0.63	GO:0005216	ion channel activity
0.50	GO:0022836	gated channel activity
0.49	GO:0015079	potassium ion transmembrane transporter activity
0.39	GO:0004692	cGMP-dependent protein kinase activity

0.46	GO:0017071	intracellular cyclic nucleotide activated cation channel complex
0.38	GO:0005887	integral component of plasma membrane
0.34	GO:0005622	intracellular

0.39

EC:2.7.11.12

GO:0004692

tr|T1FU05|T1FU05_HELRO
Histone-lysine N-methyltransferase
Search

0.42	Histone-lysine N-methyltransferase

0.84	GO:0010452	histone H3-K36 methylation
0.83	GO:0018027	peptidyl-lysine dimethylation
0.83	GO:0018026	peptidyl-lysine monomethylation
0.83	GO:0018023	peptidyl-lysine trimethylation
0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.51	GO:0051568	histone H3-K4 methylation
0.48	GO:0051149	positive regulation of muscle cell differentiation
0.48	GO:1902680	positive regulation of RNA biosynthetic process
0.48	GO:0010628	positive regulation of gene expression
0.41	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.84	GO:0046975	histone methyltransferase activity (H3-K36 specific)
0.76	GO:0003713	transcription coactivator activity
0.52	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.48	GO:0001102	RNA polymerase II activating transcription factor binding
0.32	GO:0003924	GTPase activity
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0019001	guanyl nucleotide binding
0.31	GO:0032555	purine ribonucleotide binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.48	GO:0000790	nuclear chromatin
0.33	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1FU06|T1FU06_HELRO
Uncharacterized protein
Search

0.52	Sorting nexin-27

0.69	GO:0006886	intracellular protein transport
0.60	GO:0007165	signal transduction
0.58	GO:0016197	endosomal transport
0.47	GO:0098876	vesicle-mediated transport to the plasma membrane
0.42	GO:0007041	lysosomal transport
0.35	GO:0006228	UTP biosynthetic process
0.35	GO:0006183	GTP biosynthetic process
0.35	GO:0016310	phosphorylation
0.35	GO:0046036	CTP metabolic process
0.35	GO:0005975	carbohydrate metabolic process

0.83	GO:0032266	phosphatidylinositol-3-phosphate binding
0.36	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.35	GO:0016301	kinase activity
0.35	GO:0016776	phosphotransferase activity, phosphate group as acceptor
0.35	GO:0005515	protein binding
0.34	GO:0004402	histone acetyltransferase activity
0.33	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.46	GO:0005769	early endosome
0.44	GO:0001772	immunological synapse
0.43	GO:0071203	WASH complex
0.43	GO:0030904	retromer complex
0.40	GO:0005829	cytosol
0.39	GO:0005654	nucleoplasm
0.36	GO:0010008	endosome membrane
0.36	GO:0005856	cytoskeleton
0.30	GO:0016021	integral component of membrane

0.36

GO:0004553

tr|T1FU07|T1FU07_HELRO
Uncharacterized protein
Search

tr|T1FU08|T1FU08_HELRO
Uncharacterized protein
Search

tr|T1FU09|T1FU09_HELRO
Uncharacterized protein
Search

0.51	GO:0036211	protein modification process
0.47	GO:0044267	cellular protein metabolic process
0.46	GO:0016310	phosphorylation
0.44	GO:0016569	covalent chromatin modification
0.43	GO:0007165	signal transduction
0.42	GO:0043414	macromolecule methylation
0.41	GO:0090702	non-reproductive fruiting body development
0.40	GO:0006357	regulation of transcription by RNA polymerase II
0.40	GO:0060078	regulation of postsynaptic membrane potential
0.40	GO:0007268	chemical synaptic transmission

0.49	GO:0004672	protein kinase activity
0.46	GO:0018024	histone-lysine N-methyltransferase activity
0.45	GO:0032559	adenyl ribonucleotide binding
0.44	GO:0008144	drug binding
0.44	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0046872	metal ion binding
0.41	GO:0019789	SUMO transferase activity
0.41	GO:0004888	transmembrane signaling receptor activity
0.41	GO:0005234	extracellularly glutamate-gated ion channel activity
0.40	GO:0005516	calmodulin binding

0.43	GO:0005634	nucleus
0.40	GO:0098794	postsynapse
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.46

GO:0018024

tr|T1FU10|T1FU10_HELRO
Uncharacterized protein
Search

tr|T1FU11|T1FU11_HELRO
Uncharacterized protein
Search

0.54	GO:0016573	histone acetylation
0.52	GO:0016042	lipid catabolic process
0.49	GO:1903506	regulation of nucleic acid-templated transcription
0.49	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.49	GO:0010468	regulation of gene expression
0.47	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.44	GO:0006351	transcription, DNA-templated

0.55	GO:0004402	histone acetyltransferase activity
0.49	GO:0004527	exonuclease activity
0.48	GO:0043565	sequence-specific DNA binding
0.48	GO:0004519	endonuclease activity
0.47	GO:0008270	zinc ion binding
0.46	GO:0003700	DNA binding transcription factor activity

0.57

GO:0072487

MSL complex

0.55

GO:0004402

tr|T1FU12|T1FU12_HELRO
Uncharacterized protein
Search

0.75	GO:0035335	peptidyl-tyrosine dephosphorylation
0.51	GO:0048679	regulation of axon regeneration
0.50	GO:1900121	negative regulation of receptor binding
0.50	GO:0031102	neuron projection regeneration
0.46	GO:0016477	cell migration
0.41	GO:0097374	sensory neuron axon guidance
0.38	GO:0007155	cell adhesion
0.38	GO:0034164	negative regulation of toll-like receptor 9 signaling pathway
0.38	GO:0032687	negative regulation of interferon-alpha production
0.38	GO:0050773	regulation of dendrite development

0.75	GO:0004725	protein tyrosine phosphatase activity
0.53	GO:0035373	chondroitin sulfate proteoglycan binding
0.46	GO:0032403	protein complex binding
0.40	GO:0008201	heparin binding
0.38	GO:0035374	chondroitin sulfate binding
0.36	GO:0019198	transmembrane receptor protein phosphatase activity
0.36	GO:0043395	heparan sulfate proteoglycan binding
0.34	GO:0030971	receptor tyrosine kinase binding
0.34	GO:0042301	phosphate ion binding
0.34	GO:0046872	metal ion binding

0.48	GO:0043025	neuronal cell body
0.47	GO:0043005	neuron projection
0.36	GO:0099146	intrinsic component of postsynaptic density membrane
0.36	GO:0099060	integral component of postsynaptic specialization membrane
0.36	GO:0070062	extracellular exosome
0.36	GO:0030285	integral component of synaptic vesicle membrane
0.35	GO:0005634	nucleus
0.35	GO:0030054	cell junction
0.34	GO:0060076	excitatory synapse
0.34	GO:0030427	site of polarized growth

0.75

GO:0004725

tr|T1FU13|T1FU13_HELRO
Uncharacterized protein
Search

tr|T1FU14|T1FU14_HELRO
Uncharacterized protein
Search

0.74	GO:0030036	actin cytoskeleton organization
0.68	GO:0097435	supramolecular fiber organization
0.60	GO:0007049	cell cycle
0.40	GO:0007276	gamete generation
0.39	GO:0051258	protein polymerization
0.35	GO:0007165	signal transduction
0.34	GO:0071420	cellular response to histamine
0.34	GO:0035372	protein localization to microtubule
0.33	GO:0051279	regulation of release of sequestered calcium ion into cytosol
0.33	GO:0032886	regulation of microtubule-based process

0.76	GO:0017048	Rho GTPase binding
0.74	GO:0003779	actin binding
0.44	GO:0045296	cadherin binding
0.33	GO:0044325	ion channel binding
0.33	GO:0005522	profilin binding
0.32	GO:0042802	identical protein binding
0.31	GO:0003723	RNA binding
0.30	GO:0003824	catalytic activity

0.34	GO:0005829	cytosol
0.34	GO:0005634	nucleus
0.33	GO:0072686	mitotic spindle
0.33	GO:0032587	ruffle membrane
0.33	GO:0005903	brush border
0.33	GO:0043005	neuron projection
0.32	GO:0005815	microtubule organizing center
0.30	GO:0016021	integral component of membrane

tr|T1FU15|T1FU15_HELRO
Transporter
Search

SLC6A9

0.45	Sodium- and chloride-dependent glycine transporter 1

0.76	GO:0006836	neurotransmitter transport
0.55	GO:0055085	transmembrane transport
0.50	GO:0006865	amino acid transport
0.45	GO:0060012	synaptic transmission, glycinergic
0.44	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.43	GO:0099643	signal release from synapse
0.43	GO:0046717	acid secretion
0.41	GO:0001505	regulation of neurotransmitter levels
0.41	GO:0015893	drug transport
0.40	GO:0051649	establishment of localization in cell

0.79	GO:0005328	neurotransmitter:sodium symporter activity
0.53	GO:0005283	sodium:amino acid symporter activity
0.45	GO:0015179	L-amino acid transmembrane transporter activity
0.45	GO:0015175	neutral amino acid transmembrane transporter activity
0.43	GO:0015238	drug transmembrane transporter activity
0.37	GO:0008504	monoamine transmembrane transporter activity
0.36	GO:1901618	organic hydroxy compound transmembrane transporter activity
0.35	GO:0008519	ammonium transmembrane transporter activity
0.34	GO:0015296	anion:cation symporter activity
0.33	GO:0005515	protein binding

0.50	GO:0005887	integral component of plasma membrane
0.43	GO:0098793	presynapse
0.34	GO:0043005	neuron projection

tr|T1FU16|T1FU16_HELRO
Uncharacterized protein
Search

tr|T1FU17|T1FU17_HELRO
Uncharacterized protein
Search

0.45	GO:0060255	regulation of macromolecule metabolic process
0.44	GO:0080090	regulation of primary metabolic process
0.44	GO:0031326	regulation of cellular biosynthetic process
0.44	GO:0051171	regulation of nitrogen compound metabolic process
0.39	GO:0016192	vesicle-mediated transport
0.39	GO:0036065	fucosylation
0.39	GO:0016482	cytosolic transport
0.39	GO:0016197	endosomal transport
0.39	GO:0090304	nucleic acid metabolic process
0.38	GO:0007018	microtubule-based movement

0.46	GO:0003700	DNA binding transcription factor activity
0.41	GO:0043565	sequence-specific DNA binding
0.41	GO:0046983	protein dimerization activity
0.39	GO:0008417	fucosyltransferase activity
0.38	GO:0003777	microtubule motor activity
0.37	GO:0003723	RNA binding
0.37	GO:0004518	nuclease activity
0.37	GO:0044212	transcription regulatory region DNA binding
0.36	GO:0008047	enzyme activator activity
0.36	GO:0097367	carbohydrate derivative binding

0.40	GO:0012505	endomembrane system
0.40	GO:0005634	nucleus
0.38	GO:0031984	organelle subcompartment
0.38	GO:0044444	cytoplasmic part
0.37	GO:0098588	bounding membrane of organelle
0.37	GO:0032991	macromolecular complex
0.35	GO:0043232	intracellular non-membrane-bounded organelle
0.35	GO:0043233	organelle lumen
0.35	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.39

EC:2.4.1

GO:0008417

tr|T1FU18|T1FU18_HELRO
Uncharacterized protein
Search

0.45	GO:0006629	lipid metabolic process
0.41	GO:0051568	histone H3-K4 methylation
0.41	GO:0099139	cheating during chimeric sorocarp development
0.39	GO:0016180	snRNA processing
0.39	GO:0006914	autophagy
0.38	GO:0000281	mitotic cytokinesis
0.38	GO:0006351	transcription, DNA-templated
0.37	GO:0060255	regulation of macromolecule metabolic process
0.37	GO:0080090	regulation of primary metabolic process
0.37	GO:0031323	regulation of cellular metabolic process

0.41	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.41	GO:0016787	hydrolase activity
0.40	GO:0003676	nucleic acid binding
0.39	GO:0030246	carbohydrate binding
0.39	GO:0008444	CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity
0.37	GO:0015399	primary active transmembrane transporter activity
0.37	GO:0005524	ATP binding
0.37	GO:0004672	protein kinase activity
0.37	GO:0004842	ubiquitin-protein transferase activity
0.37	GO:0008375	acetylglucosaminyltransferase activity

0.42	GO:0005634	nucleus
0.40	GO:1990234	transferase complex
0.40	GO:0031974	membrane-enclosed lumen
0.39	GO:0042641	actomyosin
0.36	GO:0005615	extracellular space
0.35	GO:0043234	protein complex
0.35	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.41	EC:3	GO:0016787
0.39	KEGG:R01801	GO:0008444

tr|T1FU19|T1FU19_HELRO
Uncharacterized protein
Search

tr|T1FU20|T1FU20_HELRO
Uncharacterized protein
Search

tr|T1FU21|T1FU21_HELRO
Uncharacterized protein
Search

tr|T1FU22|T1FU22_HELRO
Uncharacterized protein
Search

0.71	GO:0006338	chromatin remodeling
0.55	GO:0003408	optic cup formation involved in camera-type eye development
0.53	GO:0006344	maintenance of chromatin silencing
0.52	GO:0042921	glucocorticoid receptor signaling pathway
0.52	GO:0030520	intracellular estrogen receptor signaling pathway
0.52	GO:0007566	embryo implantation
0.52	GO:0060674	placenta blood vessel development
0.51	GO:0030521	androgen receptor signaling pathway
0.51	GO:0055007	cardiac muscle cell differentiation
0.51	GO:0001843	neural tube closure

0.52	GO:0016922	ligand-dependent nuclear receptor binding
0.51	GO:0003677	DNA binding
0.50	GO:0031491	nucleosome binding
0.36	GO:0003723	RNA binding
0.36	GO:0046872	metal ion binding
0.35	GO:0043130	ubiquitin binding
0.35	GO:0018024	histone-lysine N-methyltransferase activity
0.35	GO:0030674	protein binding, bridging
0.35	GO:0140110	transcription regulator activity
0.34	GO:0042802	identical protein binding

0.70	GO:0070603	SWI/SNF superfamily-type complex
0.47	GO:0097458	neuron part
0.45	GO:0005654	nucleoplasm
0.33	GO:0030131	clathrin adaptor complex
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.35

GO:0018024

tr|T1FU23|T1FU23_HELRO
Uncharacterized protein
Search

0.44	GO:0006468	protein phosphorylation
0.44	GO:0060255	regulation of macromolecule metabolic process
0.43	GO:0080090	regulation of primary metabolic process
0.43	GO:0031326	regulation of cellular biosynthetic process
0.43	GO:0051171	regulation of nitrogen compound metabolic process
0.39	GO:0016070	RNA metabolic process
0.38	GO:0010467	gene expression
0.38	GO:0065009	regulation of molecular function
0.37	GO:0009059	macromolecule biosynthetic process
0.37	GO:0036010	protein localization to endosome

0.46	GO:0003700	DNA binding transcription factor activity
0.44	GO:0004672	protein kinase activity
0.42	GO:0032559	adenyl ribonucleotide binding
0.41	GO:0008144	drug binding
0.41	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0003676	nucleic acid binding
0.41	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.38	GO:0005515	protein binding
0.38	GO:0098772	molecular function regulator
0.37	GO:0016500	protein-hormone receptor activity

0.37	GO:0005829	cytosol
0.36	GO:0005666	DNA-directed RNA polymerase III complex
0.36	GO:0005874	microtubule
0.35	GO:0005794	Golgi apparatus
0.34	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.41

GO:0003899

tr|T1FU24|T1FU24_HELRO
Uncharacterized protein
Search

0.69	GO:0006730	one-carbon metabolic process
0.35	GO:0015671	oxygen transport
0.35	GO:0035335	peptidyl-tyrosine dephosphorylation

0.76	GO:0004089	carbonate dehydratase activity
0.61	GO:0008270	zinc ion binding
0.35	GO:0005344	oxygen carrier activity
0.35	GO:0019825	oxygen binding
0.35	GO:0016151	nickel cation binding
0.35	GO:0005509	calcium ion binding
0.35	GO:0004725	protein tyrosine phosphatase activity
0.33	GO:0020037	heme binding

0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.76

EC:4.2.1.1

GO:0004089

tr|T1FU25|T1FU25_HELRO
Uncharacterized protein
Search

DHRS1

0.64	Dehydrogenase/reductase SDR family member 1

0.53

GO:0055114

oxidation-reduction process

0.54

GO:0016491

oxidoreductase activity

0.54

GO:0016491

tr|T1FU26|T1FU26_HELRO
Uncharacterized protein
Search

tr|T1FU27|T1FU27_HELRO
Uncharacterized protein
Search

tr|T1FU28|T1FU28_HELRO
Uncharacterized protein
Search

tr|T1FU29|T1FU29_HELRO
Uncharacterized protein
Search

0.42	GO:0055002	striated muscle cell development
0.39	GO:0030036	actin cytoskeleton organization
0.37	GO:0010927	cellular component assembly involved in morphogenesis
0.36	GO:0007610	behavior
0.36	GO:0120036	plasma membrane bounded cell projection organization
0.36	GO:0046716	muscle cell cellular homeostasis
0.36	GO:0097435	supramolecular fiber organization
0.36	GO:0070925	organelle assembly
0.35	GO:0048731	system development
0.35	GO:0035204	negative regulation of lamellocyte differentiation

0.71	GO:0003779	actin binding
0.45	GO:0032403	protein complex binding
0.41	GO:0030506	ankyrin binding
0.34	GO:0046872	metal ion binding
0.34	GO:0042802	identical protein binding
0.33	GO:0030246	carbohydrate binding
0.33	GO:0022857	transmembrane transporter activity

0.40	GO:0042383	sarcolemma
0.38	GO:0005829	cytosol
0.36	GO:0030018	Z disc
0.36	GO:0035182	female germline ring canal outer rim
0.35	GO:0035183	female germline ring canal inner rim
0.35	GO:0045179	apical cortex
0.35	GO:0043034	costamere
0.34	GO:0070938	contractile ring
0.34	GO:0005856	cytoskeleton
0.34	GO:0016528	sarcoplasm

tr|T1FU30|T1FU30_HELRO
Uncharacterized protein
Search

0.78	Troponin i

0.43	GO:0006936	muscle contraction
0.41	GO:0043057	backward locomotion
0.41	GO:0043050	pharyngeal pumping
0.40	GO:0045214	sarcomere organization
0.38	GO:0009792	embryo development ending in birth or egg hatching

0.48	GO:0030172	troponin C binding
0.38	GO:0003779	actin binding
0.34	GO:0046872	metal ion binding

0.83	GO:0005861	troponin complex
0.40	GO:0005862	muscle thin filament tropomyosin
0.30	GO:0031224	intrinsic component of membrane

tr|T1FU31|T1FU31_HELRO
Uncharacterized protein
Search

MRE11

0.89	Double-strand break repair protein MRE11

0.76	GO:0051321	meiotic cell cycle
0.75	GO:0006302	double-strand break repair
0.64	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.57	GO:0031860	telomeric 3' overhang formation
0.57	GO:0031573	intra-S DNA damage checkpoint
0.56	GO:0032876	negative regulation of DNA endoreduplication
0.55	GO:0031954	positive regulation of protein autophosphorylation
0.54	GO:0032206	positive regulation of telomere maintenance
0.54	GO:0007095	mitotic G2 DNA damage checkpoint
0.52	GO:0000726	non-recombinational repair

0.72	GO:0030145	manganese ion binding
0.71	GO:0008408	3'-5' exonuclease activity
0.66	GO:0004519	endonuclease activity
0.53	GO:0008022	protein C-terminus binding
0.52	GO:0045296	cadherin binding
0.49	GO:0042802	identical protein binding
0.48	GO:0004003	ATP-dependent DNA helicase activity
0.48	GO:0004536	deoxyribonuclease activity
0.41	GO:0003677	DNA binding
0.35	GO:0018024	histone-lysine N-methyltransferase activity

0.83	GO:0030870	Mre11 complex
0.54	GO:0016605	PML body
0.53	GO:0035861	site of double-strand break
0.53	GO:0000784	nuclear chromosome, telomeric region
0.38	GO:0005737	cytoplasm
0.34	GO:0000794	condensed nuclear chromosome
0.34	GO:0000790	nuclear chromatin
0.31	GO:0030529	intracellular ribonucleoprotein complex

0.35

GO:0018024

tr|T1FU32|T1FU32_HELRO
Uncharacterized protein
Search

0.74	GO:0007018	microtubule-based movement
0.56	GO:0021685	cerebellar granular layer structural organization
0.56	GO:0032487	regulation of Rap protein signal transduction
0.55	GO:0033624	negative regulation of integrin activation
0.55	GO:0021693	cerebellar Purkinje cell layer structural organization
0.53	GO:0031641	regulation of myelination
0.53	GO:0021846	cell proliferation in forebrain
0.53	GO:0021772	olfactory bulb development
0.53	GO:1903429	regulation of cell maturation
0.52	GO:0034446	substrate adhesion-dependent cell spreading

0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0030165	PDZ domain binding
0.49	GO:0019901	protein kinase binding
0.44	GO:0016887	ATPase activity
0.33	GO:0003779	actin binding

0.53	GO:0090543	Flemming body
0.53	GO:0005874	microtubule
0.51	GO:0051233	spindle midzone
0.47	GO:0005871	kinesin complex
0.45	GO:0005829	cytosol
0.40	GO:0005886	plasma membrane
0.34	GO:0005634	nucleus
0.32	GO:0000792	heterochromatin
0.30	GO:0016021	integral component of membrane

0.44

GO:0016887

tr|T1FU33|T1FU33_HELRO
Uncharacterized protein
Search

MED21

0.83	Mediator of RNA polymerase II transcription subunit 21

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.51	GO:0019827	stem cell population maintenance
0.50	GO:0001824	blastocyst development
0.46	GO:1902680	positive regulation of RNA biosynthetic process
0.37	GO:0016567	protein ubiquitination

0.52	GO:0003712	transcription cofactor activity
0.49	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.37	GO:0061630	ubiquitin protein ligase activity
0.35	GO:0005515	protein binding
0.33	GO:0003899	DNA-directed 5'-3' RNA polymerase activity

0.77	GO:0016592	mediator complex
0.37	GO:0000151	ubiquitin ligase complex

0.33

GO:0003899

tr|T1FU34|T1FU34_HELRO
Uncharacterized protein
Search

tr|T1FU35|T1FU35_HELRO
Uncharacterized protein
Search

tr|T1FU36|T1FU36_HELRO
Uncharacterized protein
Search

tr|T1FU37|T1FU37_HELRO
Uncharacterized protein
Search

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.51	GO:0006366	transcription by RNA polymerase II
0.51	GO:1902680	positive regulation of RNA biosynthetic process
0.49	GO:0050774	negative regulation of dendrite morphogenesis
0.48	GO:0001707	mesoderm formation
0.48	GO:0048484	enteric nervous system development
0.40	GO:0035015	elongation of arista core
0.39	GO:0007480	imaginal disc-derived leg morphogenesis

0.64	GO:0043565	sequence-specific DNA binding
0.54	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.48	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.47	GO:0001012	RNA polymerase II regulatory region DNA binding
0.45	GO:0003690	double-stranded DNA binding
0.34	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm
0.35	GO:0043234	protein complex

tr|T1FU38|T1FU38_HELRO
Uncharacterized protein
Search

tr|T1FU39|T1FU39_HELRO
DNA polymerase
Search

0.21	DNA polymerase

0.84	GO:0019985	translesion synthesis
0.59	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.59	GO:0006260	DNA replication
0.35	GO:0007186	G-protein coupled receptor signaling pathway

0.71	GO:0003887	DNA-directed DNA polymerase activity
0.66	GO:0008408	3'-5' exonuclease activity
0.55	GO:0051539	4 iron, 4 sulfur cluster binding
0.55	GO:0003677	DNA binding
0.53	GO:1901265	nucleoside phosphate binding
0.51	GO:0036094	small molecule binding
0.47	GO:0046872	metal ion binding
0.34	GO:0004871	signal transducer activity

0.85	GO:0016035	zeta DNA polymerase complex
0.52	GO:0005634	nucleus
0.36	GO:1905360	GTPase complex
0.36	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.36	GO:0031974	membrane-enclosed lumen
0.35	GO:0043232	intracellular non-membrane-bounded organelle
0.35	GO:0098797	plasma membrane protein complex

0.71

GO:0003887

tr|T1FU40|T1FU40_HELRO
Uncharacterized protein
Search

0.52	Ring finger protein 40

0.84	GO:0010390	histone monoubiquitination
0.35	GO:2001168	positive regulation of histone H2B ubiquitination
0.35	GO:1900364	negative regulation of mRNA polyadenylation
0.34	GO:0033523	histone H2B ubiquitination
0.34	GO:0005975	carbohydrate metabolic process
0.34	GO:0031062	positive regulation of histone methylation
0.34	GO:0030336	negative regulation of cell migration
0.34	GO:0000209	protein polyubiquitination
0.34	GO:0007219	Notch signaling pathway
0.33	GO:0045893	positive regulation of transcription, DNA-templated

0.74	GO:0004842	ubiquitin-protein transferase activity
0.50	GO:0016874	ligase activity
0.45	GO:0046872	metal ion binding
0.35	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.34	GO:0002039	p53 binding
0.34	GO:0003730	mRNA 3'-UTR binding
0.34	GO:0042393	histone binding
0.34	GO:0031625	ubiquitin protein ligase binding
0.34	GO:0003713	transcription coactivator activity
0.34	GO:0003682	chromatin binding

0.38	GO:0005634	nucleus
0.35	GO:0033503	HULC complex
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0016459	myosin complex

0.50	EC:6	GO:0016874
0.74	KEGG:R03876	GO:0004842

tr|T1FU41|T1FU41_HELRO
Uncharacterized protein
Search

0.80	GO:0045995	regulation of embryonic development
0.76	GO:0030334	regulation of cell migration
0.73	GO:0030155	regulation of cell adhesion
0.71	GO:0007155	cell adhesion
0.55	GO:0060445	branching involved in salivary gland morphogenesis
0.54	GO:0001658	branching involved in ureteric bud morphogenesis
0.54	GO:0001755	neural crest cell migration
0.53	GO:0060541	respiratory system development
0.53	GO:0001738	morphogenesis of a polarized epithelium
0.52	GO:0030323	respiratory tube development

0.70	GO:0005102	receptor binding
0.51	GO:0050839	cell adhesion molecule binding
0.49	GO:0032403	protein complex binding
0.38	GO:0003735	structural constituent of ribosome

0.57	GO:0043259	laminin-10 complex
0.55	GO:0043083	synaptic cleft
0.48	GO:0005615	extracellular space
0.42	GO:0005610	laminin-5 complex
0.40	GO:0036062	presynaptic periactive zone
0.38	GO:1903561	extracellular vesicle
0.38	GO:0043260	laminin-11 complex
0.37	GO:0005840	ribosome
0.35	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

tr|T1FU42|T1FU42_HELRO
Uncharacterized protein
Search

tr|T1FU43|T1FU43_HELRO
Uncharacterized protein
Search

tr|T1FU44|T1FU44_HELRO
Uncharacterized protein
Search

0.40	GO:0007160	cell-matrix adhesion
0.39	GO:0006751	glutathione catabolic process
0.38	GO:0005975	carbohydrate metabolic process
0.36	GO:0009057	macromolecule catabolic process
0.36	GO:0006508	proteolysis

0.40	GO:0030248	cellulose binding
0.39	GO:0036374	glutathione hydrolase activity
0.38	GO:0017056	structural constituent of nuclear pore
0.34	GO:0003676	nucleic acid binding

0.39	GO:0030014	CCR4-NOT complex
0.38	GO:0005643	nuclear pore
0.37	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.39	EC:3.4.19.13	GO:0036374
0.39	KEGG:R00494	GO:0036374

tr|T1FU45|T1FU45_HELRO
Uncharacterized protein
Search

0.71	GTP binding protein alpha subunit Gi

0.81	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.37	GO:1904778	positive regulation of protein localization to cell cortex
0.37	GO:0001973	adenosine receptor signaling pathway
0.37	GO:0007214	gamma-aminobutyric acid signaling pathway
0.36	GO:0060236	regulation of mitotic spindle organization
0.36	GO:0035690	cellular response to drug
0.36	GO:0051301	cell division
0.35	GO:1903831	signal transduction involved in cellular response to ammonium ion
0.35	GO:1905144	response to acetylcholine
0.35	GO:1901701	cellular response to oxygen-containing compound

0.81	GO:0031683	G-protein beta/gamma-subunit complex binding
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.64	GO:0004871	signal transducer activity
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0001664	G-protein coupled receptor binding
0.34	GO:0046872	metal ion binding
0.32	GO:0016773	phosphotransferase activity, alcohol group as acceptor

0.45	GO:0030425	dendrite
0.45	GO:0044297	cell body
0.44	GO:1905360	GTPase complex
0.44	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.40	GO:0098797	plasma membrane protein complex
0.38	GO:0030496	midbody
0.38	GO:0005813	centrosome
0.37	GO:0005829	cytosol
0.36	GO:0099738	cell cortex region
0.36	GO:0044428	nuclear part

0.32

GO:0016773

tr|T1FU46|T1FU46_HELRO
Uncharacterized protein
Search

tr|T1FU47|T1FU47_HELRO
Uncharacterized protein
Search

0.38	GO:0009607	response to biotic stimulus
0.38	GO:0016192	vesicle-mediated transport
0.37	GO:0006468	protein phosphorylation
0.36	GO:0098657	import into cell
0.36	GO:0046907	intracellular transport
0.36	GO:0006355	regulation of transcription, DNA-templated
0.35	GO:0070727	cellular macromolecule localization
0.35	GO:0046898	response to cycloheximide
0.35	GO:0006351	transcription, DNA-templated
0.35	GO:0015031	protein transport

0.40	GO:0005544	calcium-dependent phospholipid binding
0.38	GO:0042302	structural constituent of cuticle
0.38	GO:0005509	calcium ion binding
0.37	GO:0043565	sequence-specific DNA binding
0.37	GO:0004672	protein kinase activity
0.37	GO:0005044	scavenger receptor activity
0.36	GO:0003700	DNA binding transcription factor activity
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding

0.38	GO:0005581	collagen trimer
0.37	GO:0030660	Golgi-associated vesicle membrane
0.36	GO:0005634	nucleus
0.36	GO:0030134	COPII-coated ER to Golgi transport vesicle
0.36	GO:0030658	transport vesicle membrane
0.36	GO:0030120	vesicle coat
0.35	GO:0000139	Golgi membrane
0.34	GO:0044291	cell-cell contact zone
0.34	GO:0044432	endoplasmic reticulum part
0.34	GO:0045335	phagocytic vesicle

0.35

GO:0016887

tr|T1FU48|T1FU48_HELRO
Uncharacterized protein
Search

tr|T1FU49|T1FU49_HELRO
DNA polymerase
Search

0.25	DNA polymerase

0.67	GO:0071897	DNA biosynthetic process
0.66	GO:0006260	DNA replication
0.42	GO:0032042	mitochondrial DNA metabolic process
0.41	GO:0006287	base-excision repair, gap-filling
0.38	GO:0090305	nucleic acid phosphodiester bond hydrolysis

0.71	GO:0003887	DNA-directed DNA polymerase activity
0.55	GO:0003677	DNA binding
0.40	GO:0008408	3'-5' exonuclease activity
0.40	GO:0002020	protease binding
0.38	GO:0003682	chromatin binding
0.34	GO:0016874	ligase activity

0.85	GO:0005760	gamma DNA polymerase complex
0.39	GO:0042645	mitochondrial nucleoid
0.35	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

0.71

GO:0003887

tr|T1FU50|T1FU50_HELRO
Uncharacterized protein
Search

tr|T1FU51|T1FU51_HELRO
Uncharacterized protein
Search

tr|T1FU52|T1FU52_HELRO
Uncharacterized protein
Search

tr|T1FU53|T1FU53_HELRO
Uncharacterized protein
Search

0.77

GO:0006914

autophagy

tr|T1FU54|T1FU54_HELRO
Uncharacterized protein
Search

0.39	GO:0035556	intracellular signal transduction
0.35	GO:0005975	carbohydrate metabolic process
0.35	GO:0006508	proteolysis

0.64	GO:0005509	calcium ion binding
0.38	GO:0004563	beta-N-acetylhexosaminidase activity
0.38	GO:0005201	extracellular matrix structural constituent
0.38	GO:0004197	cysteine-type endopeptidase activity
0.34	GO:0003677	DNA binding

0.37	GO:0005578	proteinaceous extracellular matrix
0.34	GO:0005622	intracellular
0.30	GO:0044425	membrane part

0.38

EC:3.2.1.52

GO:0004563

tr|T1FU55|T1FU55_HELRO
Uncharacterized protein
Search

tr|T1FU56|T1FU56_HELRO
Uncharacterized protein
Search

tr|T1FU57|T1FU57_HELRO
Uncharacterized protein
Search

0.33	GO:0006284	base-excision repair
0.33	GO:0031110	regulation of microtubule polymerization or depolymerization

0.61	GO:0008270	zinc ion binding
0.50	GO:0003676	nucleic acid binding
0.34	GO:0003905	alkylbase DNA N-glycosylase activity

0.44	GO:0005829	cytosol
0.42	GO:0005634	nucleus
0.33	GO:0005783	endoplasmic reticulum

0.34

EC:3.2.2.21

GO:0003905

tr|T1FU58|T1FU58_HELRO
Uncharacterized protein
Search

tr|T1FU59|T1FU59_HELRO
Uncharacterized protein
Search

tr|T1FU60|T1FU60_HELRO
Uncharacterized protein
Search

tr|T1FU61|T1FU61_HELRO
Uncharacterized protein
Search

0.11	Phosphoserine phosphatase-like

0.77	GO:0006564	L-serine biosynthetic process
0.68	GO:0016311	dephosphorylation
0.37	GO:0033574	response to testosterone
0.36	GO:0009612	response to mechanical stimulus
0.35	GO:0031667	response to nutrient levels

0.81	GO:0004647	phosphoserine phosphatase activity
0.44	GO:0042803	protein homodimerization activity
0.42	GO:0005509	calcium ion binding
0.41	GO:0000287	magnesium ion binding

0.35

GO:0043005

neuron projection

0.81

EC:3.1.3.3

GO:0004647

tr|T1FU62|T1FU62_HELRO
Uncharacterized protein
Search

0.61	GO:0006508	proteolysis
0.41	GO:0007399	nervous system development
0.37	GO:0080009	mRNA methylation
0.37	GO:0006370	7-methylguanosine mRNA capping
0.34	GO:0007601	visual perception
0.34	GO:0032456	endocytic recycling
0.33	GO:0016567	protein ubiquitination
0.33	GO:0000910	cytokinesis
0.32	GO:0050896	response to stimulus
0.32	GO:0006355	regulation of transcription, DNA-templated

0.82	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.52	GO:0046872	metal ion binding
0.37	GO:0004483	mRNA (nucleoside-2'-O-)-methyltransferase activity
0.34	GO:0030306	ADP-ribosylation factor binding
0.33	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0017137	Rab GTPase binding
0.33	GO:0003676	nucleic acid binding
0.33	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.32	GO:0003700	DNA binding transcription factor activity

0.45

GO:0005622

intracellular

0.37	EC:2.1.1.57	GO:0004483
0.33	KEGG:R03876	GO:0004842

tr|T1FU63|T1FU63_HELRO
Uncharacterized protein
Search

BMS1

0.66	Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 9

0.66	GO:0042254	ribosome biogenesis
0.41	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.41	GO:0016072	rRNA metabolic process
0.40	GO:0034470	ncRNA processing
0.39	GO:0000966	RNA 5'-end processing
0.34	GO:0031016	pancreas development
0.34	GO:0001889	liver development
0.34	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:0006351	transcription, DNA-templated
0.32	GO:0043386	mycotoxin biosynthetic process

0.64	GO:0032550	purine ribonucleoside binding
0.64	GO:0019001	guanyl nucleotide binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0034511	U3 snoRNA binding
0.40	GO:0003924	GTPase activity
0.37	GO:0030554	adenyl nucleotide binding
0.37	GO:0008144	drug binding
0.34	GO:0004930	G-protein coupled receptor activity
0.34	GO:0003899	DNA-directed 5'-3' RNA polymerase activity

0.61	GO:0005634	nucleus
0.44	GO:0030686	90S preribosome
0.38	GO:0031974	membrane-enclosed lumen
0.36	GO:0043232	intracellular non-membrane-bounded organelle
0.36	GO:0044446	intracellular organelle part
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.34

GO:0003899

tr|T1FU64|T1FU64_HELRO
Uncharacterized protein
Search

tr|T1FU65|T1FU65_HELRO
Uncharacterized protein
Search

0.60	GO:0007165	signal transduction
0.60	GO:1901386	negative regulation of voltage-gated calcium channel activity
0.52	GO:1901841	regulation of high voltage-gated calcium channel activity
0.37	GO:0042423	catecholamine biosynthetic process
0.36	GO:0045943	positive regulation of transcription by RNA polymerase I
0.35	GO:0009072	aromatic amino acid family metabolic process
0.33	GO:0055114	oxidation-reduction process

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0004511	tyrosine 3-monooxygenase activity
0.34	GO:0005506	iron ion binding

0.39	GO:0009898	cytoplasmic side of plasma membrane
0.35	GO:0005730	nucleolus

0.37

EC:1.14.16.2

GO:0004511

tr|T1FU66|T1FU66_HELRO
Uncharacterized protein
Search

0.10	Neurexin-4

0.56	GO:0021678	third ventricle development
0.55	GO:0021670	lateral ventricle development
0.54	GO:0003351	epithelial cilium movement
0.54	GO:0060972	left/right pattern formation
0.53	GO:0030317	flagellated sperm motility
0.52	GO:0007368	determination of left/right symmetry
0.51	GO:0007283	spermatogenesis
0.34	GO:0007229	integrin-mediated signaling pathway
0.34	GO:0007155	cell adhesion

0.39	GO:0008897	holo-[acyl-carrier-protein] synthase activity
0.37	GO:0000287	magnesium ion binding
0.34	GO:0005509	calcium ion binding
0.33	GO:0005515	protein binding

0.34	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.39

EC:2.7.8.7

GO:0008897

tr|T1FU67|T1FU67_HELRO
Uncharacterized protein
Search

0.63	probable ubiquitin carboxyl-terminal hydrolase FAF-X

0.76	GO:0016579	protein deubiquitination
0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.47	GO:0016477	cell migration
0.47	GO:0030509	BMP signaling pathway
0.47	GO:0048675	axon extension
0.47	GO:0007179	transforming growth factor beta receptor signaling pathway
0.38	GO:0021698	cerebellar cortex structural organization
0.37	GO:0021766	hippocampus development
0.36	GO:0001701	in utero embryonic development
0.36	GO:0009791	post-embryonic development

0.77	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.49	GO:0070410	co-SMAD binding
0.33	GO:0004197	cysteine-type endopeptidase activity

0.47	GO:0030426	growth cone
0.37	GO:0005737	cytoplasm
0.36	GO:0045177	apical part of cell
0.30	GO:0016020	membrane

0.77

EC:3.4.19.12

GO:0036459

tr|T1FU68|T1FU68_HELRO
Uncharacterized protein
Search

0.53	Small subunit ribosomal protein S23e

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.39	GO:0034063	stress granule assembly

0.64

GO:0003735

structural constituent of ribosome

0.70	GO:0015935	small ribosomal subunit
0.48	GO:0022626	cytosolic ribosome
0.43	GO:0042788	polysomal ribosome
0.38	GO:0005783	endoplasmic reticulum
0.34	GO:0098562	cytoplasmic side of membrane
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

tr|T1FU69|T1FU69_HELRO
Uncharacterized protein
Search

tr|T1FU70|T1FU70_HELRO
Uncharacterized protein
Search

0.72	GO:0035023	regulation of Rho protein signal transduction
0.62	GO:0065009	regulation of molecular function
0.40	GO:0043534	blood vessel endothelial cell migration
0.39	GO:0007369	gastrulation
0.39	GO:0001525	angiogenesis
0.37	GO:0000256	allantoin catabolic process
0.37	GO:0060255	regulation of macromolecule metabolic process
0.36	GO:0080090	regulation of primary metabolic process
0.36	GO:0031326	regulation of cellular biosynthetic process
0.36	GO:0051171	regulation of nitrogen compound metabolic process

0.72	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.37	GO:0003700	DNA binding transcription factor activity
0.37	GO:0004037	allantoicase activity
0.36	GO:0018024	histone-lysine N-methyltransferase activity
0.35	GO:0046872	metal ion binding
0.35	GO:0000829	inositol heptakisphosphate kinase activity
0.35	GO:0042578	phosphoric ester hydrolase activity
0.34	GO:0035091	phosphatidylinositol binding
0.34	GO:0003723	RNA binding
0.33	GO:0032559	adenyl ribonucleotide binding

0.32	GO:0005622	intracellular
0.30	GO:0016020	membrane

0.37	EC:3.5.3.4	GO:0004037
0.37	KEGG:R02422	GO:0004037

tr|T1FU71|T1FU71_HELRO
Uncharacterized protein
Search

tr|T1FU72|T1FU72_HELRO
NAD(P)H-hydrate epimerase
Search

0.32	NAD(P)H-hydrate epimerase

0.51	GO:0051289	protein homotetramerization
0.48	GO:0019362	pyridine nucleotide metabolic process
0.35	GO:0031580	membrane raft distribution
0.35	GO:0010874	regulation of cholesterol efflux
0.35	GO:0002040	sprouting angiogenesis
0.34	GO:0016525	negative regulation of angiogenesis
0.34	GO:0006836	neurotransmitter transport
0.33	GO:0072525	pyridine-containing compound biosynthetic process
0.33	GO:0009108	coenzyme biosynthetic process
0.33	GO:0009165	nucleotide biosynthetic process

0.77	GO:0052856	NADHX epimerase activity
0.52	GO:0046872	metal ion binding
0.51	GO:1901265	nucleoside phosphate binding
0.50	GO:0036094	small molecule binding
0.49	GO:0052857	NADPHX epimerase activity
0.47	GO:0042803	protein homodimerization activity
0.34	GO:0052855	ADP-dependent NAD(P)H-hydrate dehydratase activity
0.34	GO:0008641	ubiquitin-like modifier activating enzyme activity
0.34	GO:0005328	neurotransmitter:sodium symporter activity
0.32	GO:0016787	hydrolase activity

0.53	GO:0005576	extracellular region
0.52	GO:0005739	mitochondrion
0.49	GO:0044297	cell body
0.48	GO:0005929	cilium
0.45	GO:0005654	nucleoplasm
0.45	GO:0005829	cytosol
0.35	GO:0031982	vesicle
0.30	GO:0031224	intrinsic component of membrane

0.77

EC:5.1

GO:0052856

tr|T1FU73|T1FU73_HELRO
Uncharacterized protein
Search

0.53	2-oxoglutarate dehydrogenase, mitochondrial

0.71	GO:0006099	tricarboxylic acid cycle
0.46	GO:0090501	RNA phosphodiester bond hydrolysis
0.45	GO:0008033	tRNA processing
0.37	GO:0061034	olfactory bulb mitral cell layer development
0.36	GO:0018335	protein succinylation
0.36	GO:0021860	pyramidal neuron development
0.36	GO:0022028	tangential migration from the subventricular zone to the olfactory bulb
0.36	GO:0021794	thalamus development
0.36	GO:0021756	striatum development
0.36	GO:0006104	succinyl-CoA metabolic process

0.80	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity
0.73	GO:0030976	thiamine pyrophosphate binding
0.46	GO:0004540	ribonuclease activity
0.37	GO:0034602	oxoglutarate dehydrogenase (NAD+) activity
0.32	GO:0046872	metal ion binding

0.39	GO:0045252	oxoglutarate dehydrogenase complex
0.36	GO:0005739	mitochondrion
0.36	GO:0005829	cytosol
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0005634	nucleus
0.33	GO:0044446	intracellular organelle part

0.80	EC:1.2.4.2	GO:0004591
0.37	KEGG:R08549	GO:0034602

tr|T1FU74|T1FU74_HELRO
Uncharacterized protein
Search

tr|T1FU75|T1FU75_HELRO
Uncharacterized protein
Search

tr|T1FU76|T1FU76_HELRO
Stathmin
Search

0.57

Stathmin

0.84

GO:0031110

regulation of microtubule polymerization or depolymerization

tr|T1FU77|T1FU77_HELRO
Uncharacterized protein
Search

tr|T1FU78|T1FU78_HELRO
Uncharacterized protein
Search

0.49	GO:0036211	protein modification process
0.48	GO:0016569	covalent chromatin modification
0.47	GO:0044267	cellular protein metabolic process
0.43	GO:0016310	phosphorylation
0.43	GO:0006030	chitin metabolic process
0.43	GO:0043414	macromolecule methylation
0.42	GO:0019985	translesion synthesis
0.42	GO:0006888	ER to Golgi vesicle-mediated transport
0.41	GO:0006873	cellular ion homeostasis
0.40	GO:0006886	intracellular protein transport

0.47	GO:0140096	catalytic activity, acting on a protein
0.47	GO:0016278	lysine N-methyltransferase activity
0.45	GO:0016772	transferase activity, transferring phosphorus-containing groups
0.43	GO:0046872	metal ion binding
0.42	GO:0008061	chitin binding
0.42	GO:0003713	transcription coactivator activity
0.41	GO:0003676	nucleic acid binding
0.41	GO:0046982	protein heterodimerization activity
0.41	GO:0000166	nucleotide binding
0.40	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding

0.45	GO:0005634	nucleus
0.44	GO:0061695	transferase complex, transferring phosphorus-containing groups
0.43	GO:0030127	COPII vesicle coat
0.41	GO:1902493	acetyltransferase complex
0.41	GO:0000139	Golgi membrane
0.41	GO:0005667	transcription factor complex
0.41	GO:0005789	endoplasmic reticulum membrane
0.40	GO:1905368	peptidase complex
0.40	GO:0005576	extracellular region
0.39	GO:0031974	membrane-enclosed lumen

0.47

GO:0016278

tr|T1FU79|T1FU79_HELRO
Uncharacterized protein
Search

0.54	GO:0007264	small GTPase mediated signal transduction
0.49	GO:0065009	regulation of molecular function
0.46	GO:0006396	RNA processing

0.53	GO:0005085	guanyl-nucleotide exchange factor activity
0.53	GO:0004000	adenosine deaminase activity
0.44	GO:0003723	RNA binding

0.38	GO:0005622	intracellular
0.30	GO:0044425	membrane part

0.53

EC:3.5.4.4

GO:0004000

tr|T1FU80|T1FU80_HELRO
Transcription elongation factor SPT5
Search

SUPT5H

0.66	Transcription elongation factor SPT5

0.71	GO:0032784	regulation of DNA-templated transcription, elongation
0.67	GO:0006357	regulation of transcription by RNA polymerase II
0.58	GO:0006414	translational elongation
0.54	GO:0006351	transcription, DNA-templated
0.51	GO:1900364	negative regulation of mRNA polyadenylation
0.49	GO:0016239	positive regulation of macroautophagy
0.45	GO:0045893	positive regulation of transcription, DNA-templated
0.45	GO:0045892	negative regulation of transcription, DNA-templated
0.43	GO:0006397	mRNA processing
0.35	GO:1902038	positive regulation of hematopoietic stem cell differentiation

0.59	GO:0003746	translation elongation factor activity
0.46	GO:0046982	protein heterodimerization activity
0.45	GO:0003682	chromatin binding
0.45	GO:0003729	mRNA binding
0.45	GO:0019899	enzyme binding
0.39	GO:0003677	DNA binding
0.34	GO:0000339	RNA cap binding
0.33	GO:0003743	translation initiation factor activity

0.57	GO:0005634	nucleus
0.46	GO:0031974	membrane-enclosed lumen
0.43	GO:0043234	protein complex
0.42	GO:0044446	intracellular organelle part
0.35	GO:0000428	DNA-directed RNA polymerase complex
0.34	GO:0016282	eukaryotic 43S preinitiation complex
0.34	GO:0033290	eukaryotic 48S preinitiation complex

tr|T1FU81|T1FU81_HELRO
Uncharacterized protein
Search

0.53	GO:0051649	establishment of localization in cell
0.52	GO:0070727	cellular macromolecule localization
0.50	GO:0015031	protein transport
0.46	GO:0006468	protein phosphorylation
0.42	GO:0065007	biological regulation
0.42	GO:0030154	cell differentiation
0.42	GO:0007275	multicellular organism development
0.41	GO:0071840	cellular component organization or biogenesis
0.41	GO:0007154	cell communication
0.40	GO:0050896	response to stimulus

0.59	GO:0017137	Rab GTPase binding
0.46	GO:0046872	metal ion binding
0.46	GO:0004672	protein kinase activity
0.42	GO:0030554	adenyl nucleotide binding
0.42	GO:0097367	carbohydrate derivative binding
0.42	GO:0008144	drug binding
0.42	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0140110	transcription regulator activity
0.40	GO:0003676	nucleic acid binding
0.38	GO:0050825	ice binding

0.45	GO:0005634	nucleus
0.41	GO:0099738	cell cortex region
0.41	GO:0099569	presynaptic cytoskeleton
0.40	GO:0000785	chromatin
0.40	GO:0070013	intracellular organelle lumen
0.39	GO:0048786	presynaptic active zone
0.39	GO:0030863	cortical cytoskeleton
0.38	GO:0032991	macromolecular complex
0.36	GO:0045177	apical part of cell
0.36	GO:0000324	fungal-type vacuole

0.36

GO:0000179

tr|T1FU82|T1FU82_HELRO
Uncharacterized protein
Search

0.60	GO:0006468	protein phosphorylation
0.42	GO:0009816	defense response to bacterium, incompatible interaction
0.41	GO:0006623	protein targeting to vacuole
0.37	GO:0035973	aggrephagy
0.37	GO:0045022	early endosome to late endosome transport
0.36	GO:0043248	proteasome assembly
0.36	GO:0043551	regulation of phosphatidylinositol 3-kinase activity
0.35	GO:0006511	ubiquitin-dependent protein catabolic process
0.35	GO:0005975	carbohydrate metabolic process
0.34	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process

0.61	GO:0004672	protein kinase activity
0.52	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0035014	phosphatidylinositol 3-kinase regulator activity
0.35	GO:0004588	orotate phosphoribosyltransferase activity
0.35	GO:0004590	orotidine-5'-phosphate decarboxylase activity
0.34	GO:0005515	protein binding
0.32	GO:0003723	RNA binding

0.37	GO:0031313	extrinsic component of endosome membrane
0.37	GO:0080008	Cul4-RING E3 ubiquitin ligase complex
0.36	GO:0000421	autophagosome membrane
0.36	GO:0031901	early endosome membrane
0.36	GO:0031902	late endosome membrane
0.36	GO:0005765	lysosomal membrane
0.34	GO:0005829	cytosol
0.34	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

0.35	EC:2.4.2.10	GO:0004588
0.35	KEGG:R00965	GO:0004590

tr|T1FU83|T1FU83_HELRO
Uncharacterized protein
Search

tr|T1FU84|T1FU84_HELRO
Uncharacterized protein
Search

0.81	Septin-7 isoform B

0.41	GO:0072114	pronephros morphogenesis
0.40	GO:0060271	cilium assembly
0.37	GO:0051301	cell division
0.37	GO:0017157	regulation of exocytosis
0.37	GO:0007049	cell cycle
0.36	GO:0090163	establishment of epithelial cell planar polarity
0.35	GO:0060031	mediolateral intercalation
0.35	GO:0016476	regulation of embryonic cell shape

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity
0.34	GO:0003924	GTPase activity

0.69	GO:0031105	septin complex
0.37	GO:0008021	synaptic vesicle
0.36	GO:0005940	septin ring
0.35	GO:0032154	cleavage furrow
0.35	GO:0030496	midbody
0.34	GO:0005930	axoneme
0.34	GO:0016324	apical plasma membrane
0.34	GO:0000777	condensed chromosome kinetochore
0.34	GO:0005819	spindle
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:2.8.2.8

GO:0015016

tr|T1FU85|T1FU85_HELRO
Uncharacterized protein
Search

tr|T1FU86|T1FU86_HELRO
Uncharacterized protein
Search

tr|T1FU87|T1FU87_HELRO
Uncharacterized protein
Search

HEXB

0.37	Beta-hexosaminidase

0.60	GO:0005975	carbohydrate metabolic process
0.47	GO:0043615	astrocyte cell migration
0.46	GO:0007341	penetration of zona pellucida
0.46	GO:0006689	ganglioside catabolic process
0.45	GO:0050885	neuromuscular process controlling balance
0.45	GO:0008049	male courtship behavior
0.45	GO:0001525	angiogenesis
0.45	GO:0042552	myelination
0.45	GO:0007040	lysosome organization
0.45	GO:0019915	lipid storage

0.79	GO:0004563	beta-N-acetylhexosaminidase activity
0.72	GO:0102148	N-acetyl-beta-D-galactosaminidase activity
0.42	GO:0008375	acetylglucosaminyltransferase activity
0.42	GO:0042803	protein homodimerization activity
0.42	GO:0046982	protein heterodimerization activity
0.34	GO:0005230	extracellular ligand-gated ion channel activity
0.34	GO:0030246	carbohydrate binding

0.45	GO:0042582	azurophil granule
0.44	GO:0001669	acrosomal vesicle
0.41	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.35	GO:0043202	lysosomal lumen
0.35	GO:0034774	secretory granule lumen
0.33	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.79

EC:3.2.1.52

GO:0004563

tr|T1FU88|T1FU88_HELRO
Uncharacterized protein
Search

0.72	GO:0031122	cytoplasmic microtubule organization
0.70	GO:0007020	microtubule nucleation
0.41	GO:0000212	meiotic spindle organization
0.36	GO:1902408	mitotic cytokinesis, site selection
0.36	GO:0007052	mitotic spindle organization
0.35	GO:0051255	spindle midzone assembly
0.35	GO:0051231	spindle elongation
0.35	GO:0000070	mitotic sister chromatid segregation
0.34	GO:0007346	regulation of mitotic cell cycle
0.34	GO:0010564	regulation of cell cycle process

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.58	GO:0005200	structural constituent of cytoskeleton
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0042802	identical protein binding
0.33	GO:0008097	5S rRNA binding
0.32	GO:0003735	structural constituent of ribosome

0.73	GO:0005874	microtubule
0.72	GO:0000930	gamma-tubulin complex
0.45	GO:0000242	pericentriolar material
0.43	GO:0005819	spindle
0.41	GO:0055037	recycling endosome
0.41	GO:0005814	centriole
0.40	GO:0036064	ciliary basal body
0.40	GO:0097730	non-motile cilium
0.40	GO:0045177	apical part of cell
0.40	GO:0031252	cell leading edge

tr|T1FU89|T1FU89_HELRO
Uncharacterized protein
Search

0.43	GO:0030245	cellulose catabolic process
0.41	GO:0006888	ER to Golgi vesicle-mediated transport
0.40	GO:0007018	microtubule-based movement
0.39	GO:0016567	protein ubiquitination
0.38	GO:0006364	rRNA processing
0.37	GO:0006281	DNA repair
0.37	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.36	GO:0055114	oxidation-reduction process
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.44	GO:0030248	cellulose binding
0.44	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.43	GO:0050825	ice binding
0.41	GO:0005507	copper ion binding
0.40	GO:0004040	amidase activity
0.40	GO:0003777	microtubule motor activity
0.39	GO:0004842	ubiquitin-protein transferase activity
0.38	GO:0003684	damaged DNA binding
0.38	GO:0043565	sequence-specific DNA binding
0.38	GO:0032550	purine ribonucleoside binding

0.48	GO:0070701	mucus layer
0.41	GO:0032040	small-subunit processome
0.39	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.44	EC:3.2.1	GO:0004553
0.39	KEGG:R03876	GO:0004842

tr|T1FU90|T1FU90_HELRO
Uncharacterized protein
Search

0.16	Nuclear RNA export factor 1

0.79	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.76	GO:0051028	mRNA transport
0.74	GO:0006405	RNA export from nucleus
0.53	GO:0010467	gene expression

0.58

GO:0003723

RNA binding

0.61	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm

tr|T1FU91|T1FU91_HELRO
Uncharacterized protein
Search

0.52	GO:0018095	protein polyglutamylation
0.44	GO:2001141	regulation of RNA biosynthetic process
0.44	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.44	GO:0010468	regulation of gene expression
0.43	GO:0006351	transcription, DNA-templated
0.40	GO:0006629	lipid metabolic process
0.40	GO:0031156	regulation of sorocarp development
0.40	GO:0051254	positive regulation of RNA metabolic process
0.40	GO:0010557	positive regulation of macromolecule biosynthetic process
0.40	GO:0031328	positive regulation of cellular biosynthetic process

0.46	GO:0046983	protein dimerization activity
0.43	GO:0030554	adenyl nucleotide binding
0.43	GO:0097367	carbohydrate derivative binding
0.43	GO:0008144	drug binding
0.43	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0003676	nucleic acid binding
0.39	GO:0004672	protein kinase activity
0.39	GO:0003700	DNA binding transcription factor activity
0.39	GO:0016787	hydrolase activity
0.37	GO:0008134	transcription factor binding

0.47	GO:0005634	nucleus
0.40	GO:0061695	transferase complex, transferring phosphorus-containing groups
0.39	GO:0070013	intracellular organelle lumen
0.38	GO:0044446	intracellular organelle part
0.38	GO:0043234	protein complex
0.37	GO:0005856	cytoskeleton
0.36	GO:0005615	extracellular space
0.35	GO:0005694	chromosome
0.35	GO:0044444	cytoplasmic part
0.30	GO:0016020	membrane

0.39

GO:0016787

tr|T1FU92|T1FU92_HELRO
Amino acid transporter
Search

0.30	Amino acid transporter

0.55	GO:0055085	transmembrane transport
0.38	GO:0008345	larval locomotory behavior

0.72

GO:0015293

symporter activity

0.30

GO:0031224

intrinsic component of membrane

tr|T1FU93|T1FU93_HELRO
Uncharacterized protein
Search

tr|T1FU94|T1FU94_HELRO
Uncharacterized protein
Search

tr|T1FU95|T1FU95_HELRO
Uncharacterized protein
Search

tr|T1FU96|T1FU96_HELRO
Uncharacterized protein
Search

0.53	GO:0016032	viral process
0.39	GO:0000056	ribosomal small subunit export from nucleus
0.37	GO:0042274	ribosomal small subunit biogenesis
0.35	GO:0006950	response to stress

0.39	GO:0005199	structural constituent of cell wall
0.37	GO:0030246	carbohydrate binding
0.34	GO:0003676	nucleic acid binding

0.55	GO:0036338	viral membrane
0.38	GO:0071339	MLL1 complex
0.38	GO:0048188	Set1C/COMPASS complex
0.37	GO:0005618	cell wall
0.36	GO:0005576	extracellular region
0.30	GO:0016020	membrane

tr|T1FU97|T1FU97_HELRO
Uncharacterized protein
Search

0.53	GO:0036211	protein modification process
0.50	GO:0044267	cellular protein metabolic process
0.48	GO:0016310	phosphorylation
0.39	GO:0030707	ovarian follicle cell development
0.39	GO:0048749	compound eye development
0.39	GO:0016569	covalent chromatin modification
0.39	GO:0048674	collateral sprouting of injured axon
0.39	GO:0031660	regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle
0.38	GO:0048569	post-embryonic animal organ development
0.38	GO:2001141	regulation of RNA biosynthetic process

0.60	GO:0035091	phosphatidylinositol binding
0.52	GO:0004672	protein kinase activity
0.47	GO:0030554	adenyl nucleotide binding
0.47	GO:0008144	drug binding
0.46	GO:0097367	carbohydrate derivative binding
0.46	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0004842	ubiquitin-protein transferase activity
0.39	GO:0018024	histone-lysine N-methyltransferase activity
0.38	GO:0008270	zinc ion binding
0.38	GO:0043565	sequence-specific DNA binding

0.41	GO:0005634	nucleus
0.38	GO:0005694	chromosome
0.37	GO:0043234	protein complex
0.36	GO:0098805	whole membrane
0.36	GO:0098588	bounding membrane of organelle
0.35	GO:0044446	intracellular organelle part
0.35	GO:0038201	TOR complex
0.35	GO:0030137	COPI-coated vesicle
0.35	GO:0000151	ubiquitin ligase complex
0.35	GO:0012506	vesicle membrane

0.39	EC:2.1.1.43	GO:0018024
0.46	KEGG:R03876	GO:0004842

tr|T1FU98|T1FU98_HELRO
Uncharacterized protein
Search

tr|T1FU99|T1FU99_HELRO
Uncharacterized protein
Search

tr|T1FUA0|T1FUA0_HELRO
Uncharacterized protein
Search

tr|T1FUA1|T1FUA1_HELRO
Uncharacterized protein
Search

tr|T1FUA2|T1FUA2_HELRO
Uncharacterized protein
Search

0.43	GO:0007084	mitotic nuclear envelope reassembly
0.42	GO:0035307	positive regulation of protein dephosphorylation
0.42	GO:0042244	spore wall assembly
0.36	GO:0016310	phosphorylation
0.36	GO:2001141	regulation of RNA biosynthetic process
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:0010468	regulation of gene expression

0.43	GO:0051721	protein phosphatase 2A binding
0.41	GO:0030248	cellulose binding
0.41	GO:0016740	transferase activity
0.38	GO:0003676	nucleic acid binding
0.37	GO:0008270	zinc ion binding

0.43	GO:0070701	mucus layer
0.42	GO:0031160	spore wall
0.42	GO:0090665	glycoprotein complex
0.39	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.41

GO:0016740

tr|T1FUA3|T1FUA3_HELRO
Uncharacterized protein
Search

tr|T1FUA4|T1FUA4_HELRO
Uncharacterized protein
Search

0.45

GO:0006950

response to stress

0.41

GO:0003677

DNA binding

0.30

GO:0044425

membrane part

tr|T1FUA5|T1FUA5_HELRO
Uncharacterized protein
Search

tr|T1FUA6|T1FUA6_HELRO
Uncharacterized protein
Search

tr|T1FUA7|T1FUA7_HELRO
Uncharacterized protein
Search

0.39	GO:0007155	cell adhesion
0.39	GO:0007399	nervous system development
0.38	GO:0030154	cell differentiation

0.38

GO:0030246

carbohydrate binding

0.46	GO:0070701	mucus layer
0.30	GO:0044425	membrane part

tr|T1FUA8|T1FUA8_HELRO
Uncharacterized protein
Search

0.69

GO:0006364

rRNA processing

0.83	GO:0030688	preribosome, small subunit precursor
0.39	GO:0030687	preribosome, large subunit precursor
0.36	GO:0005634	nucleus

tr|T1FUA9|T1FUA9_HELRO
Uncharacterized protein
Search

0.51	GO:0006468	protein phosphorylation
0.45	GO:0046854	phosphatidylinositol phosphorylation
0.39	GO:0045433	male courtship behavior, veined wing generated song production
0.39	GO:0007474	imaginal disc-derived wing vein specification
0.39	GO:0018212	peptidyl-tyrosine modification
0.38	GO:0019226	transmission of nerve impulse
0.38	GO:0042552	myelination
0.38	GO:0016043	cellular component organization
0.38	GO:0007422	peripheral nervous system development
0.38	GO:0006928	movement of cell or subcellular component

0.53	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.52	GO:0016301	kinase activity
0.48	GO:0030554	adenyl nucleotide binding
0.48	GO:0140096	catalytic activity, acting on a protein
0.47	GO:0097367	carbohydrate derivative binding
0.47	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0008144	drug binding
0.43	GO:0005509	calcium ion binding
0.41	GO:0005515	protein binding
0.37	GO:0003682	chromatin binding

0.39	GO:0035102	PRC1 complex
0.38	GO:0035098	ESC/E(Z) complex
0.38	GO:0005700	polytene chromosome
0.37	GO:0005813	centrosome
0.37	GO:0033010	paranodal junction
0.37	GO:0043194	axon initial segment
0.36	GO:0033270	paranode region of axon
0.36	GO:0043209	myelin sheath
0.34	GO:0005829	cytosol
0.33	GO:0005886	plasma membrane

0.53	EC:2.7.1	GO:0016773
0.35	KEGG:R01220	GO:0004488

tr|T1FUB0|T1FUB0_HELRO
Uncharacterized protein
Search

0.73	GO:0040008	regulation of growth
0.69	GO:0016567	protein ubiquitination
0.60	GO:0035556	intracellular signal transduction
0.49	GO:0050868	negative regulation of T cell activation
0.48	GO:0010498	proteasomal protein catabolic process
0.47	GO:0046426	negative regulation of JAK-STAT cascade
0.45	GO:0006469	negative regulation of protein kinase activity
0.45	GO:0019221	cytokine-mediated signaling pathway
0.36	GO:0001678	cellular glucose homeostasis
0.35	GO:0006886	intracellular protein transport

0.46	GO:0004860	protein kinase inhibitor activity
0.38	GO:0003723	RNA binding
0.34	GO:0004430	1-phosphatidylinositol 4-kinase activity
0.34	GO:0005515	protein binding
0.33	GO:0018024	histone-lysine N-methyltransferase activity
0.33	GO:0046872	metal ion binding
0.33	GO:0051539	4 iron, 4 sulfur cluster binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.52	GO:0001772	immunological synapse
0.44	GO:0005622	intracellular
0.36	GO:0048475	coated membrane
0.34	GO:0098796	membrane protein complex
0.32	GO:0043227	membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.34	EC:2.7.1.67	GO:0004430
0.34	KEGG:R03361	GO:0004430

tr|T1FUB1|T1FUB1_HELRO
Uncharacterized protein
Search

HSP70

0.50	Heat shock 70 kDa protein cognate

0.41	GO:0006616	SRP-dependent cotranslational protein targeting to membrane, translocation
0.39	GO:0006457	protein folding
0.38	GO:0030163	protein catabolic process
0.37	GO:0071211	protein targeting to vacuole involved in autophagy
0.37	GO:0072318	clathrin coat disassembly
0.37	GO:0006622	protein targeting to lysosome
0.37	GO:0034605	cellular response to heat
0.36	GO:0090344	negative regulation of cell aging
0.36	GO:0044265	cellular macromolecule catabolic process
0.36	GO:1902904	negative regulation of supramolecular fiber organization

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0051082	unfolded protein binding
0.37	GO:0055131	C3HC4-type RING finger domain binding
0.36	GO:0045296	cadherin binding
0.36	GO:0016887	ATPase activity
0.36	GO:0001664	G-protein coupled receptor binding
0.36	GO:0031625	ubiquitin protein ligase binding

0.37	GO:0005829	cytosol
0.36	GO:0000974	Prp19 complex
0.36	GO:0005634	nucleus
0.36	GO:0101031	chaperone complex
0.36	GO:0070062	extracellular exosome
0.36	GO:0005844	polysome
0.36	GO:0009277	fungal-type cell wall
0.36	GO:0000329	fungal-type vacuole membrane
0.35	GO:0000151	ubiquitin ligase complex
0.34	GO:0043209	myelin sheath

0.36

GO:0016887

tr|T1FUB2|T1FUB2_HELRO
Uncharacterized protein
Search

0.49	GO:0006364	rRNA processing
0.47	GO:0016925	protein sumoylation
0.40	GO:0006468	protein phosphorylation
0.38	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway
0.37	GO:0006491	N-glycan processing
0.37	GO:0016575	histone deacetylation
0.36	GO:0007018	microtubule-based movement
0.36	GO:0042274	ribosomal small subunit biogenesis
0.36	GO:0001522	pseudouridine synthesis
0.35	GO:0018209	peptidyl-serine modification

0.48	GO:0019948	SUMO activating enzyme activity
0.42	GO:0032559	adenyl ribonucleotide binding
0.42	GO:0003723	RNA binding
0.41	GO:0008144	drug binding
0.41	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.40	GO:0016301	kinase activity
0.40	GO:0140096	catalytic activity, acting on a protein
0.40	GO:0046872	metal ion binding
0.37	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity

0.56	GO:0030688	preribosome, small subunit precursor
0.39	GO:0005634	nucleus
0.36	GO:0000139	Golgi membrane
0.35	GO:0005783	endoplasmic reticulum
0.35	GO:0031974	membrane-enclosed lumen
0.35	GO:0043232	intracellular non-membrane-bounded organelle
0.34	GO:0042555	MCM complex
0.34	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

0.41	EC:2.7.1	GO:0016773
0.37	KEGG:R05982 KEGG:R06722	GO:0004571

tr|T1FUB3|T1FUB3_HELRO
Uncharacterized protein
Search

tr|T1FUB4|T1FUB4_HELRO
Uncharacterized protein
Search

tr|T1FUB5|T1FUB5_HELRO
Uncharacterized protein
Search

tr|T1FUB6|T1FUB6_HELRO
Uncharacterized protein
Search

0.81	GO:0007076	mitotic chromosome condensation
0.61	GO:0051301	cell division
0.46	GO:0010032	meiotic chromosome condensation
0.43	GO:0051304	chromosome separation
0.37	GO:0010469	regulation of receptor activity
0.36	GO:0071266	'de novo' L-methionine biosynthetic process
0.34	GO:1903342	negative regulation of meiotic DNA double-strand break formation
0.34	GO:0043007	maintenance of rDNA
0.34	GO:0070058	tRNA gene clustering
0.34	GO:0007130	synaptonemal complex assembly

0.43	GO:0042393	histone binding
0.42	GO:0003682	chromatin binding
0.37	GO:0005179	hormone activity
0.37	GO:0004121	cystathionine beta-lyase activity
0.35	GO:0070279	vitamin B6 binding
0.34	GO:0050662	coenzyme binding
0.34	GO:0003723	RNA binding
0.34	GO:0004743	pyruvate kinase activity
0.34	GO:0030955	potassium ion binding
0.33	GO:0043168	anion binding

0.61	GO:0005634	nucleus
0.44	GO:0000796	condensin complex
0.43	GO:0000779	condensed chromosome, centromeric region
0.40	GO:0043233	organelle lumen
0.35	GO:0005576	extracellular region
0.34	GO:0035327	transcriptionally active chromatin
0.33	GO:0000776	kinetochore
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.37

EC:4.4.1.8

GO:0004121

tr|T1FUB7|T1FUB7_HELRO
Uncharacterized protein
Search

0.47	GO:0018095	protein polyglutamylation
0.42	GO:0016310	phosphorylation
0.41	GO:0065007	biological regulation
0.38	GO:0007010	cytoskeleton organization
0.38	GO:0043326	chemotaxis to folate
0.38	GO:0009451	RNA modification
0.37	GO:0043327	chemotaxis to cAMP
0.37	GO:0070925	organelle assembly
0.37	GO:0007017	microtubule-based process
0.37	GO:0022402	cell cycle process

0.49	GO:0000829	inositol heptakisphosphate kinase activity
0.42	GO:0030554	adenyl nucleotide binding
0.42	GO:0097367	carbohydrate derivative binding
0.42	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0008144	drug binding
0.40	GO:0004674	protein serine/threonine kinase activity
0.40	GO:0003676	nucleic acid binding
0.39	GO:0019899	enzyme binding
0.39	GO:0003700	DNA binding transcription factor activity
0.38	GO:0042578	phosphoric ester hydrolase activity

0.40	GO:0005634	nucleus
0.39	GO:0044430	cytoskeletal part
0.37	GO:0015630	microtubule cytoskeleton
0.37	GO:0005667	transcription factor complex
0.36	GO:0097422	tubular endosome
0.36	GO:0015629	actin cytoskeleton
0.36	GO:0005615	extracellular space
0.35	GO:0005770	late endosome
0.35	GO:0005769	early endosome
0.35	GO:0099512	supramolecular fiber

0.40	EC:2.7.11	GO:0004674
0.35	KEGG:R01801	GO:0008444

tr|T1FUB8|T1FUB8_HELRO
Uncharacterized protein
Search

tr|T1FUB9|T1FUB9_HELRO
Uncharacterized protein
Search

NDEL1-B

0.82	Nuclear distribution protein nudE 1-A

0.82	GO:2000574	regulation of microtubule motor activity
0.54	GO:0007100	mitotic centrosome separation
0.52	GO:0060052	neurofilament cytoskeleton organization
0.47	GO:0007399	nervous system development
0.41	GO:0047496	vesicle transport along microtubule
0.41	GO:0000132	establishment of mitotic spindle orientation
0.41	GO:0051303	establishment of chromosome localization
0.41	GO:0051642	centrosome localization
0.40	GO:0007020	microtubule nucleation
0.40	GO:0016477	cell migration

0.39	GO:0008017	microtubule binding
0.37	GO:0005247	voltage-gated chloride channel activity
0.36	GO:0042802	identical protein binding
0.36	GO:0004672	protein kinase activity
0.35	GO:0008168	methyltransferase activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0008144	drug binding
0.34	GO:0045330	aspartyl esterase activity
0.34	GO:0030599	pectinesterase activity

0.40	GO:0000776	kinetochore
0.40	GO:0005813	centrosome
0.39	GO:0005871	kinesin complex
0.38	GO:0005819	spindle
0.37	GO:0045202	synapse
0.34	GO:0005874	microtubule
0.34	GO:0005618	cell wall
0.32	GO:0005737	cytoplasm
0.32	GO:0005886	plasma membrane
0.32	GO:0005634	nucleus

0.35	EC:2.1.1	GO:0008168
0.33	KEGG:R02728	GO:0008801

tr|T1FUC0|T1FUC0_HELRO
Uncharacterized protein
Search

0.48	GO:0009298	GDP-mannose biosynthetic process
0.44	GO:0006629	lipid metabolic process
0.42	GO:2001141	regulation of RNA biosynthetic process
0.42	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.41	GO:0010468	regulation of gene expression
0.41	GO:0005975	carbohydrate metabolic process
0.40	GO:0036211	protein modification process
0.39	GO:0016310	phosphorylation
0.39	GO:0048015	phosphatidylinositol-mediated signaling
0.38	GO:0044267	cellular protein metabolic process

0.49	GO:0004806	triglyceride lipase activity
0.48	GO:0004476	mannose-6-phosphate isomerase activity
0.44	GO:0003700	DNA binding transcription factor activity
0.43	GO:0003723	RNA binding
0.42	GO:0008270	zinc ion binding
0.40	GO:0016301	kinase activity
0.39	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.39	GO:0030554	adenyl nucleotide binding
0.39	GO:0140096	catalytic activity, acting on a protein
0.38	GO:0097367	carbohydrate derivative binding

0.39	GO:0005634	nucleus
0.38	GO:0005875	microtubule associated complex
0.38	GO:0005628	prospore membrane
0.37	GO:0030124	AP-4 adaptor complex
0.36	GO:1902494	catalytic complex
0.36	GO:0071561	nucleus-vacuole junction
0.35	GO:1990816	vacuole-mitochondrion membrane contact site
0.35	GO:0072686	mitotic spindle
0.34	GO:0000785	chromatin
0.34	GO:0019898	extrinsic component of membrane

0.49	EC:3.1.1.3	GO:0004806
0.35	KEGG:R01213	GO:0003852

tr|T1FUC1|T1FUC1_HELRO
Uncharacterized protein
Search

CMTR1

0.84	Cap-specific mRNA (Nucleoside-2'-O-)-methyltransferase

0.79	GO:0080009	mRNA methylation
0.74	GO:0006370	7-methylguanosine mRNA capping

0.81	GO:0004483	mRNA (nucleoside-2'-O-)-methyltransferase activity
0.50	GO:0003676	nucleic acid binding

0.35	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.81

EC:2.1.1.57

GO:0004483

tr|T1FUC2|T1FUC2_HELRO
Uncharacterized protein
Search

0.33

GO:0032774

RNA biosynthetic process

0.51	GO:0003676	nucleic acid binding
0.34	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.33	GO:0008270	zinc ion binding

0.30

GO:0044425

membrane part

0.34

GO:0003899

tr|T1FUC3|T1FUC3_HELRO
Uncharacterized protein
Search

0.51	GO:0016310	phosphorylation
0.46	GO:0042048	olfactory behavior
0.46	GO:0045471	response to ethanol
0.46	GO:0007613	memory
0.45	GO:0050803	regulation of synapse structure or activity
0.35	GO:0009967	positive regulation of signal transduction
0.33	GO:0007186	G-protein coupled receptor signaling pathway

0.53	GO:0016301	kinase activity
0.43	GO:0043565	sequence-specific DNA binding
0.37	GO:0005070	SH3/SH2 adaptor activity
0.33	GO:0004930	G-protein coupled receptor activity
0.33	GO:0030246	carbohydrate binding

0.43	GO:0045202	synapse
0.42	GO:0005634	nucleus
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1FUC4|T1FUC4_HELRO
Nucleolar GTP-binding protein 2
Search

GNL2

0.73	Nucleolar GTP-binding protein 2

0.43	GO:0001654	eye development
0.42	GO:0090596	sensory organ morphogenesis
0.41	GO:0042254	ribosome biogenesis
0.37	GO:0007096	regulation of exit from mitosis
0.36	GO:0045664	regulation of neuron differentiation
0.35	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.35	GO:0016072	rRNA metabolic process
0.35	GO:0034470	ncRNA processing
0.34	GO:0035307	positive regulation of protein dephosphorylation

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0003924	GTPase activity
0.33	GO:0003723	RNA binding

0.73	GO:0005730	nucleolus
0.39	GO:0005654	nucleoplasm
0.34	GO:0071595	Nem1-Spo7 phosphatase complex
0.30	GO:0031224	intrinsic component of membrane

tr|T1FUC5|T1FUC5_HELRO
Uncharacterized protein
Search

0.74	GO:0007018	microtubule-based movement
0.45	GO:0090307	mitotic spindle assembly
0.43	GO:0030334	regulation of cell migration
0.36	GO:0007399	nervous system development
0.36	GO:0030154	cell differentiation
0.35	GO:0051301	cell division
0.35	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.35	GO:0007019	microtubule depolymerization
0.34	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.34	GO:0007062	sister chromatid cohesion

0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0016887	ATPase activity
0.34	GO:0019901	protein kinase binding

0.71	GO:0005874	microtubule
0.46	GO:0120103	centriolar subdistal appendage
0.45	GO:0097228	sperm principal piece
0.44	GO:0005814	centriole
0.43	GO:0000922	spindle pole
0.43	GO:0005871	kinesin complex
0.43	GO:0005813	centrosome
0.42	GO:0016604	nuclear body
0.41	GO:0005730	nucleolus
0.34	GO:0005764	lysosome

0.38

GO:0016887

tr|T1FUC6|T1FUC6_HELRO
Uncharacterized protein
Search

0.78	GO:0016573	histone acetylation
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.49	GO:0007464	R3/R4 cell fate commitment
0.49	GO:0040040	thermosensory behavior
0.49	GO:0045466	R7 cell differentiation
0.48	GO:0045475	locomotor rhythm
0.48	GO:0008347	glial cell migration
0.47	GO:0000076	DNA replication checkpoint

0.80	GO:0004402	histone acetyltransferase activity
0.76	GO:0003712	transcription cofactor activity
0.63	GO:0008270	zinc ion binding
0.49	GO:1990226	histone methyltransferase binding
0.47	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.43	GO:0008134	transcription factor binding
0.34	GO:0031369	translation initiation factor binding
0.34	GO:0016849	phosphorus-oxygen lyase activity
0.33	GO:0003743	translation initiation factor activity
0.32	GO:1901265	nucleoside phosphate binding

0.68	GO:0000123	histone acetyltransferase complex
0.47	GO:0005700	polytene chromosome
0.45	GO:0035097	histone methyltransferase complex
0.45	GO:0098793	presynapse
0.40	GO:0043234	protein complex
0.34	GO:0005681	spliceosomal complex
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.80

GO:0004402

tr|T1FUC7|T1FUC7_HELRO
Uncharacterized protein
Search

tr|T1FUC8|T1FUC8_HELRO
Uncharacterized protein
Search

0.44	GO:0016567	protein ubiquitination
0.39	GO:0009789	positive regulation of abscisic acid-activated signaling pathway
0.38	GO:0006511	ubiquitin-dependent protein catabolic process
0.38	GO:0009737	response to abscisic acid
0.37	GO:0009414	response to water deprivation
0.37	GO:0009651	response to salt stress
0.37	GO:0006189	'de novo' IMP biosynthetic process
0.35	GO:0010498	proteasomal protein catabolic process
0.35	GO:0006520	cellular amino acid metabolic process
0.35	GO:0001707	mesoderm formation

0.46	GO:0008270	zinc ion binding
0.43	GO:0016874	ligase activity
0.39	GO:0061630	ubiquitin protein ligase activity
0.38	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity
0.38	GO:0004644	phosphoribosylglycinamide formyltransferase activity
0.38	GO:0070546	L-phenylalanine aminotransferase activity
0.36	GO:0030170	pyridoxal phosphate binding
0.32	GO:0003677	DNA binding

0.42	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0005768	endosome
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.43	EC:6	GO:0016874
0.38	KEGG:R00355	GO:0004069

tr|T1FUC9|T1FUC9_HELRO
Uncharacterized protein
Search

tr|T1FUD0|T1FUD0_HELRO
Uncharacterized protein
Search

tr|T1FUD1|T1FUD1_HELRO
Uncharacterized protein
Search

0.39	GO:0006364	rRNA processing
0.36	GO:0016567	protein ubiquitination
0.36	GO:0000128	flocculation
0.36	GO:0006367	transcription initiation from RNA polymerase II promoter
0.36	GO:0006907	pinocytosis
0.36	GO:0023051	regulation of signaling
0.35	GO:0051276	chromosome organization
0.35	GO:0034976	response to endoplasmic reticulum stress
0.35	GO:0098813	nuclear chromosome segregation
0.35	GO:0042274	ribosomal small subunit biogenesis

0.49	GO:0003676	nucleic acid binding
0.36	GO:0004842	ubiquitin-protein transferase activity
0.35	GO:0017056	structural constituent of nuclear pore
0.35	GO:0008484	sulfuric ester hydrolase activity
0.34	GO:0005509	calcium ion binding
0.34	GO:0004672	protein kinase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0003700	DNA binding transcription factor activity

0.42	GO:0032040	small-subunit processome
0.38	GO:0005634	nucleus
0.36	GO:0031974	membrane-enclosed lumen
0.36	GO:0000428	DNA-directed RNA polymerase complex
0.35	GO:0005667	transcription factor complex
0.35	GO:0044446	intracellular organelle part
0.34	GO:0043232	intracellular non-membrane-bounded organelle
0.34	GO:0012505	endomembrane system
0.33	GO:0031975	envelope
0.33	GO:0005886	plasma membrane

0.35	EC:3.1.6	GO:0008484
0.36	KEGG:R03876	GO:0004842

tr|T1FUD2|T1FUD2_HELRO
Uncharacterized protein
Search

tr|T1FUD3|T1FUD3_HELRO
Uncharacterized protein
Search

XRCC6

0.83	X-ray repair complementing defective repair in Chinese hamster cells 6

0.81	GO:0006303	double-strand break repair via nonhomologous end joining
0.79	GO:0000723	telomere maintenance
0.70	GO:0032392	DNA geometric change
0.54	GO:0071480	cellular response to gamma radiation
0.54	GO:0051290	protein heterotetramerization
0.52	GO:0048660	regulation of smooth muscle cell proliferation
0.51	GO:0002218	activation of innate immune response
0.50	GO:0045860	positive regulation of protein kinase activity
0.48	GO:0045944	positive regulation of transcription by RNA polymerase II
0.47	GO:0045892	negative regulation of transcription, DNA-templated

0.82	GO:0042162	telomeric DNA binding
0.73	GO:0003684	damaged DNA binding
0.72	GO:0004003	ATP-dependent DNA helicase activity
0.55	GO:0051575	5'-deoxyribose-5-phosphate lyase activity
0.51	GO:0008022	protein C-terminus binding
0.51	GO:0030332	cyclin binding
0.48	GO:0044212	transcription regulatory region DNA binding
0.47	GO:0003690	double-stranded DNA binding
0.46	GO:0044877	macromolecular complex binding
0.35	GO:0003723	RNA binding

0.84	GO:0043564	Ku70:Ku80 complex
0.55	GO:0070419	nonhomologous end joining complex
0.50	GO:0000784	nuclear chromosome, telomeric region
0.48	GO:0005667	transcription factor complex
0.47	GO:0005730	nucleolus
0.47	GO:0032993	protein-DNA complex
0.46	GO:0005654	nucleoplasm
0.34	GO:0005737	cytoplasm
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016020	membrane

tr|T1FUD4|T1FUD4_HELRO
Uncharacterized protein
Search

IRAK4

0.54	Interleukin 1 receptor associated kinase 4

0.63	GO:0006468	protein phosphorylation
0.50	GO:0002446	neutrophil mediated immunity
0.49	GO:1990266	neutrophil migration
0.48	GO:0001816	cytokine production
0.48	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.48	GO:0007154	cell communication
0.46	GO:0071345	cellular response to cytokine stimulus
0.46	GO:0023052	signaling
0.43	GO:0009856	pollination
0.43	GO:0008037	cell recognition

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0005149	interleukin-1 receptor binding
0.48	GO:0030246	carbohydrate binding
0.47	GO:0000287	magnesium ion binding
0.38	GO:0001871	pattern binding
0.37	GO:0099600	transmembrane receptor activity
0.37	GO:0005509	calcium ion binding

0.39	GO:0005615	extracellular space
0.36	GO:0005634	nucleus
0.34	GO:0005886	plasma membrane
0.34	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

tr|T1FUD5|T1FUD5_HELRO
Uncharacterized protein
Search

tr|T1FUD6|T1FUD6_HELRO
Uncharacterized protein
Search

tr|T1FUD7|T1FUD7_HELRO
Uncharacterized protein
Search

COPS3

0.87	COP9 constitutive photomorphogenic homolog subunit 3

0.53	GO:0000338	protein deneddylation
0.46	GO:0001701	in utero embryonic development
0.43	GO:0048140	male germ-line cyst encapsulation
0.43	GO:0048142	germarium-derived cystoblast division
0.42	GO:0036099	female germ-line stem cell population maintenance
0.41	GO:0006511	ubiquitin-dependent protein catabolic process
0.40	GO:0050821	protein stabilization
0.40	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle
0.34	GO:0043687	post-translational protein modification
0.34	GO:0000715	nucleotide-excision repair, DNA damage recognition

0.34	GO:0005515	protein binding
0.33	GO:0098772	molecular function regulator
0.32	GO:0016301	kinase activity

0.81	GO:0008180	COP9 signalosome
0.45	GO:0005829	cytosol
0.45	GO:0005654	nucleoplasm
0.36	GO:1905369	endopeptidase complex
0.30	GO:0016020	membrane

tr|T1FUD8|T1FUD8_HELRO
Uncharacterized protein
Search

tr|T1FUD9|T1FUD9_HELRO
Uncharacterized protein
Search

0.38	GO:0048015	phosphatidylinositol-mediated signaling
0.37	GO:0046854	phosphatidylinositol phosphorylation
0.37	GO:0035073	pupariation
0.37	GO:0006429	leucyl-tRNA aminoacylation
0.37	GO:0016569	covalent chromatin modification
0.36	GO:0035076	ecdysone receptor-mediated signaling pathway
0.36	GO:0042766	nucleosome mobilization
0.36	GO:0046426	negative regulation of JAK-STAT cascade
0.36	GO:0045747	positive regulation of Notch signaling pathway
0.36	GO:0106074	aminoacyl-tRNA metabolism involved in translational fidelity

0.81	GO:0140034	methylation-dependent protein binding
0.77	GO:0042393	histone binding
0.52	GO:0046872	metal ion binding
0.37	GO:0004823	leucine-tRNA ligase activity
0.37	GO:0070615	nucleosome-dependent ATPase activity
0.36	GO:0016922	ligand-dependent nuclear receptor binding
0.36	GO:0140033	acetylation-dependent protein binding
0.36	GO:0002161	aminoacyl-tRNA editing activity
0.35	GO:0004402	histone acetyltransferase activity
0.35	GO:0004430	1-phosphatidylinositol 4-kinase activity

0.81	GO:0016589	NURF complex
0.33	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.37	EC:6.1.1.4	GO:0004823
0.37	KEGG:R03657	GO:0004823

tr|T1FUE0|T1FUE0_HELRO
Uncharacterized protein
Search

tr|T1FUE1|T1FUE1_HELRO
Uncharacterized protein
Search

SPAST

0.70

Spastin

0.68	GO:0034214	protein hexamerization
0.68	GO:0031117	positive regulation of microtubule depolymerization
0.68	GO:0051013	microtubule severing
0.59	GO:0007409	axonogenesis
0.58	GO:0006888	ER to Golgi vesicle-mediated transport
0.56	GO:0019896	axonal transport of mitochondrion
0.56	GO:0032506	cytokinetic process
0.55	GO:0051228	mitotic spindle disassembly
0.55	GO:0008089	anterograde axonal transport
0.54	GO:0090148	membrane fission

0.68	GO:0008568	microtubule-severing ATPase activity
0.58	GO:0008017	microtubule binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0043014	alpha-tubulin binding
0.52	GO:0048487	beta-tubulin binding
0.34	GO:0032403	protein complex binding
0.33	GO:0008324	cation transmembrane transporter activity

0.59	GO:0005815	microtubule organizing center
0.59	GO:0005819	spindle
0.58	GO:0048471	perinuclear region of cytoplasm
0.57	GO:0005874	microtubule
0.56	GO:0030496	midbody
0.54	GO:1904115	axon cytoplasm
0.52	GO:0005768	endosome
0.51	GO:0031965	nuclear membrane
0.49	GO:0005783	endoplasmic reticulum
0.46	GO:0005654	nucleoplasm

0.68

EC:3.6.4.3

GO:0008568

tr|T1FUE2|T1FUE2_HELRO
Uncharacterized protein
Search

0.42	GO:0006325	chromatin organization
0.41	GO:0018022	peptidyl-lysine methylation
0.38	GO:0007162	negative regulation of cell adhesion
0.38	GO:0060255	regulation of macromolecule metabolic process
0.37	GO:0080090	regulation of primary metabolic process
0.37	GO:0031326	regulation of cellular biosynthetic process
0.37	GO:0051171	regulation of nitrogen compound metabolic process
0.36	GO:0035246	peptidyl-arginine N-methylation
0.36	GO:0006468	protein phosphorylation
0.35	GO:0048208	COPII vesicle coating

0.42	GO:0003676	nucleic acid binding
0.42	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.39	GO:0046872	metal ion binding
0.38	GO:0003700	DNA binding transcription factor activity
0.38	GO:0032555	purine ribonucleotide binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0030554	adenyl nucleotide binding
0.37	GO:0008144	drug binding
0.37	GO:0004386	helicase activity
0.36	GO:0045735	nutrient reservoir activity

0.43	GO:0005634	nucleus
0.42	GO:0034708	methyltransferase complex
0.40	GO:0031974	membrane-enclosed lumen
0.38	GO:0044446	intracellular organelle part
0.34	GO:0000015	phosphopyruvate hydratase complex
0.34	GO:0005886	plasma membrane
0.34	GO:0005794	Golgi apparatus
0.34	GO:0098588	bounding membrane of organelle
0.34	GO:0005783	endoplasmic reticulum
0.30	GO:0031224	intrinsic component of membrane

0.35	EC:3.4	GO:0008233
0.35	KEGG:R00310	GO:0004325

tr|T1FUE3|T1FUE3_HELRO
Uncharacterized protein
Search

0.60	GO:0006508	proteolysis
0.55	GO:0007229	integrin-mediated signaling pathway
0.43	GO:2000391	positive regulation of neutrophil extravasation
0.42	GO:0051044	positive regulation of membrane protein ectodomain proteolysis
0.42	GO:2000415	positive regulation of fibronectin-dependent thymocyte migration
0.41	GO:0071456	cellular response to hypoxia
0.41	GO:2000309	positive regulation of tumor necrosis factor (ligand) superfamily member 11 production
0.41	GO:2000418	positive regulation of eosinophil migration
0.41	GO:0070245	positive regulation of thymocyte apoptotic process
0.41	GO:0033089	positive regulation of T cell differentiation in thymus

0.70	GO:0004222	metalloendopeptidase activity
0.53	GO:0046872	metal ion binding
0.42	GO:0005515	protein binding
0.41	GO:0090729	toxin activity
0.35	GO:0016504	peptidase activator activity
0.33	GO:0016301	kinase activity
0.32	GO:0004842	ubiquitin-protein transferase activity
0.32	GO:0050660	flavin adenine dinucleotide binding
0.32	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors
0.32	GO:0016874	ligase activity

0.44	GO:0032127	dense core granule membrane
0.43	GO:0071065	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex
0.43	GO:0032010	phagolysosome
0.42	GO:0070820	tertiary granule
0.42	GO:0042581	specific granule
0.42	GO:0002102	podosome
0.41	GO:0071133	alpha9-beta1 integrin-ADAM8 complex
0.39	GO:0009986	cell surface
0.39	GO:0005794	Golgi apparatus
0.38	GO:0005887	integral component of plasma membrane

0.70	EC:3.4.24	GO:0004222
0.32	KEGG:R03876	GO:0004842

tr|T1FUE4|T1FUE4_HELRO
Uncharacterized protein
Search

0.61	GO:0034389	lipid particle organization
0.61	GO:1903513	endoplasmic reticulum to cytosol transport
0.61	GO:0032527	protein exit from endoplasmic reticulum
0.58	GO:0030433	ubiquitin-dependent ERAD pathway
0.53	GO:0043086	negative regulation of catalytic activity
0.41	GO:0006986	response to unfolded protein
0.38	GO:0043312	neutrophil degranulation
0.36	GO:0044782	cilium organization
0.35	GO:0007186	G-protein coupled receptor signaling pathway

0.64	GO:0035473	lipase binding
0.61	GO:0055102	lipase inhibitor activity
0.58	GO:0043130	ubiquitin binding
0.57	GO:0031625	ubiquitin protein ligase binding
0.35	GO:0004930	G-protein coupled receptor activity
0.33	GO:0003723	RNA binding

0.62	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex
0.60	GO:0005811	lipid droplet
0.38	GO:0035578	azurophil granule lumen
0.36	GO:0036064	ciliary basal body
0.36	GO:0005813	centrosome
0.35	GO:0005576	extracellular region
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

tr|T1FUE5|T1FUE5_HELRO
Uncharacterized protein
Search

tr|T1FUE6|T1FUE6_HELRO
Uncharacterized protein
Search

tr|T1FUE7|T1FUE7_HELRO
Uncharacterized protein
Search

tr|T1FUE8|T1FUE8_HELRO
Uncharacterized protein
Search

tr|T1FUE9|T1FUE9_HELRO
Uncharacterized protein
Search

0.76	GO:0010951	negative regulation of endopeptidase activity
0.70	GO:0007596	blood coagulation

0.79	GO:0004867	serine-type endopeptidase inhibitor activity
0.71	GO:0008201	heparin binding

0.66	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

tr|T1FUF0|T1FUF0_HELRO
Uncharacterized protein
Search

0.50	GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.49	GO:0007219	Notch signaling pathway
0.45	GO:0045892	negative regulation of transcription, DNA-templated
0.41	GO:0000413	protein peptidyl-prolyl isomerization
0.39	GO:0032259	methylation
0.38	GO:0006468	protein phosphorylation

0.47	GO:0003682	chromatin binding
0.45	GO:0003676	nucleic acid binding
0.45	GO:0008270	zinc ion binding
0.42	GO:0008171	O-methyltransferase activity
0.41	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.39	GO:0004386	helicase activity
0.39	GO:0032559	adenyl ribonucleotide binding
0.39	GO:0004672	protein kinase activity
0.38	GO:0008144	drug binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding

0.52	GO:0005730	nucleolus
0.47	GO:0030684	preribosome
0.30	GO:0031224	intrinsic component of membrane

0.42

GO:0008171

tr|T1FUF1|T1FUF1_HELRO
Uncharacterized protein
Search

tr|T1FUF2|T1FUF2_HELRO
Uncharacterized protein
Search

0.45	GO:0035023	regulation of Rho protein signal transduction
0.44	GO:1903452	positive regulation of G1 to G0 transition
0.44	GO:0033234	negative regulation of protein sumoylation
0.42	GO:0003407	neural retina development
0.42	GO:0065009	regulation of molecular function
0.41	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.41	GO:0032465	regulation of cytokinesis
0.40	GO:0016567	protein ubiquitination
0.39	GO:0006260	DNA replication
0.39	GO:0016310	phosphorylation

0.64	GO:0051010	microtubule plus-end binding
0.51	GO:0005509	calcium ion binding
0.48	GO:0017016	Ras GTPase binding
0.45	GO:0005085	guanyl-nucleotide exchange factor activity
0.43	GO:0030306	ADP-ribosylation factor binding
0.41	GO:0061630	ubiquitin protein ligase activity
0.40	GO:0042803	protein homodimerization activity
0.40	GO:0016301	kinase activity
0.37	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.37	GO:0003723	RNA binding

0.65	GO:0035371	microtubule plus-end
0.63	GO:0005881	cytoplasmic microtubule
0.44	GO:0033768	SUMO-targeted ubiquitin ligase complex
0.43	GO:0055038	recycling endosome membrane
0.42	GO:0032154	cleavage furrow
0.42	GO:0030496	midbody
0.41	GO:0030139	endocytic vesicle
0.41	GO:0048471	perinuclear region of cytoplasm
0.41	GO:0005875	microtubule associated complex

0.37

GO:0016773

tr|T1FUF3|T1FUF3_HELRO
Uncharacterized protein
Search

tr|T1FUF4|T1FUF4_HELRO
Uncharacterized protein
Search

tr|T1FUF5|T1FUF5_HELRO
Uncharacterized protein
Search

tr|T1FUF6|T1FUF6_HELRO
Uncharacterized protein
Search

tr|T1FUF7|T1FUF7_HELRO
Uncharacterized protein
Search

0.75	GO:1904684	negative regulation of metalloendopeptidase activity
0.73	GO:0001955	blood vessel maturation
0.72	GO:0007566	embryo implantation
0.71	GO:0035115	embryonic forelimb morphogenesis
0.70	GO:0030334	regulation of cell migration
0.68	GO:2000146	negative regulation of cell motility
0.66	GO:0030198	extracellular matrix organization
0.56	GO:1990791	dorsal root ganglion development
0.53	GO:1903670	regulation of sprouting angiogenesis
0.53	GO:0002040	sprouting angiogenesis

0.65	GO:0030414	peptidase inhibitor activity
0.64	GO:0061135	endopeptidase regulator activity
0.39	GO:0005509	calcium ion binding
0.39	GO:0008233	peptidase activity
0.36	GO:0005515	protein binding
0.34	GO:0017171	serine hydrolase activity
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0032561	guanyl ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.48	GO:0005886	plasma membrane
0.42	GO:0031225	anchored component of membrane
0.39	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.39

GO:0008233

tr|T1FUF8|T1FUF8_HELRO
Uncharacterized protein
Search

0.57	GO:0035088	establishment or maintenance of apical/basal cell polarity
0.57	GO:0021747	cochlear nucleus development
0.57	GO:0016080	synaptic vesicle targeting
0.56	GO:0071896	protein localization to adherens junction
0.55	GO:0001921	positive regulation of receptor recycling
0.55	GO:0060561	apoptotic process involved in morphogenesis
0.55	GO:0060088	auditory receptor cell stereocilium organization
0.55	GO:0061162	establishment of monopolar cell polarity
0.55	GO:0060603	mammary gland duct morphogenesis
0.54	GO:0050918	positive chemotaxis

0.52	GO:0035255	ionotropic glutamate receptor binding
0.52	GO:0045296	cadherin binding
0.48	GO:0004385	guanylate kinase activity
0.35	GO:0004842	ubiquitin-protein transferase activity
0.34	GO:0046982	protein heterodimerization activity

0.57	GO:0034750	Scrib-APC-beta-catenin complex
0.56	GO:0035748	myelin sheath abaxonal region
0.55	GO:0016323	basolateral plasma membrane
0.54	GO:0042734	presynaptic membrane
0.54	GO:0045211	postsynaptic membrane
0.53	GO:0044291	cell-cell contact zone
0.53	GO:0005829	cytosol
0.53	GO:0005913	cell-cell adherens junction
0.52	GO:0031252	cell leading edge
0.50	GO:0008328	ionotropic glutamate receptor complex

0.48	EC:2.7.4.8	GO:0004385
0.35	KEGG:R03876	GO:0004842

tr|T1FUF9|T1FUF9_HELRO
Uncharacterized protein
Search

0.30

GO:0044425

membrane part

tr|T1FUG0|T1FUG0_HELRO
Uncharacterized protein
Search

tr|T1FUG1|T1FUG1_HELRO
Sulfhydryl oxidase
Search

0.30	Sulfhydryl oxidase

0.64	GO:0045454	cell redox homeostasis
0.52	GO:0055114	oxidation-reduction process
0.36	GO:0016242	negative regulation of macroautophagy
0.35	GO:0034453	microtubule anchoring

0.84	GO:0016972	thiol oxidase activity
0.41	GO:0003756	protein disulfide isomerase activity
0.34	GO:0008017	microtubule binding

0.42	GO:0005794	Golgi apparatus
0.40	GO:0005654	nucleoplasm
0.40	GO:0031301	integral component of organelle membrane
0.39	GO:0005615	extracellular space
0.38	GO:0098588	bounding membrane of organelle
0.38	GO:0031984	organelle subcompartment
0.36	GO:0045171	intercellular bridge
0.36	GO:1903561	extracellular vesicle
0.35	GO:0005813	centrosome

0.84

EC:1.8.3.2

GO:0016972

tr|T1FUG2|T1FUG2_HELRO
Uncharacterized protein
Search

0.67	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening
0.48	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.43	GO:0046856	phosphatidylinositol dephosphorylation
0.38	GO:0006351	transcription, DNA-templated
0.38	GO:1903506	regulation of nucleic acid-templated transcription
0.38	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.50	GO:0004527	exonuclease activity
0.45	GO:0004519	endonuclease activity
0.42	GO:0004540	ribonuclease activity
0.39	GO:0003723	RNA binding
0.37	GO:0046872	metal ion binding

0.67	GO:0030015	CCR4-NOT core complex
0.65	GO:0000932	P-body
0.39	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|T1FUG3|T1FUG3_HELRO
Uncharacterized protein
Search

0.63	GO:0032380	regulation of intracellular sterol transport
0.62	GO:0051000	positive regulation of nitric-oxide synthase activity
0.62	GO:0019408	dolichol biosynthetic process
0.60	GO:0032374	regulation of cholesterol transport
0.60	GO:0043536	positive regulation of blood vessel endothelial cell migration
0.60	GO:0038084	vascular endothelial growth factor signaling pathway
0.59	GO:0035268	protein mannosylation
0.59	GO:0042632	cholesterol homeostasis
0.38	GO:0001525	angiogenesis
0.37	GO:0030154	cell differentiation

0.69	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups
0.34	GO:0000287	magnesium ion binding

0.52	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

0.69

EC:2.5 EC:2.5.1

GO:0016765

tr|T1FUG4|T1FUG4_HELRO
Uncharacterized protein
Search

0.62	GO:0018395	peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine
0.62	GO:0070079	histone H4-R3 demethylation
0.62	GO:0070078	histone H3-R2 demethylation
0.57	GO:0006909	phagocytosis
0.56	GO:0002040	sprouting angiogenesis
0.56	GO:0048024	regulation of mRNA splicing, via spliceosome
0.55	GO:0048821	erythrocyte development
0.54	GO:0033077	T cell differentiation in thymus
0.54	GO:0042116	macrophage activation
0.54	GO:0032259	methylation

0.62	GO:0033749	histone demethylase activity (H4-R3 specific)
0.62	GO:0033746	histone demethylase activity (H3-R2 specific)
0.59	GO:0070815	peptidyl-lysine 5-dioxygenase activity
0.54	GO:0008168	methyltransferase activity
0.54	GO:0003727	single-stranded RNA binding
0.50	GO:0042802	identical protein binding
0.46	GO:0046983	protein dimerization activity
0.45	GO:0004872	receptor activity
0.45	GO:0005506	iron ion binding
0.34	GO:0005216	ion channel activity

0.51	GO:0005730	nucleolus
0.50	GO:0005654	nucleoplasm
0.47	GO:0005829	cytosol
0.43	GO:0030529	intracellular ribonucleoprotein complex
0.41	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.54

GO:0008168

tr|T1FUG5|T1FUG5_HELRO
Uncharacterized protein
Search

0.48	GO:0006177	GMP biosynthetic process
0.43	GO:0043044	ATP-dependent chromatin remodeling
0.41	GO:0010556	regulation of macromolecule biosynthetic process
0.41	GO:0080090	regulation of primary metabolic process
0.41	GO:0031326	regulation of cellular biosynthetic process
0.41	GO:0051171	regulation of nitrogen compound metabolic process
0.41	GO:0030522	intracellular receptor signaling pathway
0.41	GO:0043401	steroid hormone mediated signaling pathway
0.40	GO:0098507	polynucleotide 5' dephosphorylation
0.40	GO:0045005	DNA-dependent DNA replication maintenance of fidelity

0.49	GO:0003938	IMP dehydrogenase activity
0.45	GO:0046872	metal ion binding
0.42	GO:0004887	thyroid hormone receptor activity
0.42	GO:0044212	transcription regulatory region DNA binding
0.42	GO:1901265	nucleoside phosphate binding
0.41	GO:0003707	steroid hormone receptor activity
0.41	GO:0003723	RNA binding
0.41	GO:0036094	small molecule binding
0.41	GO:0004651	polynucleotide 5'-phosphatase activity
0.40	GO:0003712	transcription cofactor activity

0.45	GO:0070603	SWI/SNF superfamily-type complex
0.41	GO:0000124	SAGA complex
0.40	GO:0097458	neuron part
0.30	GO:0031224	intrinsic component of membrane

0.49

EC:1.1.1.205

GO:0003938

tr|T1FUG6|T1FUG6_HELRO
Uncharacterized protein
Search

tr|T1FUG7|T1FUG7_HELRO
Uncharacterized protein
Search

tr|T1FUG8|T1FUG8_HELRO
Uncharacterized protein
Search

tr|T1FUG9|T1FUG9_HELRO
Uncharacterized protein
Search

0.42	GO:2001141	regulation of RNA biosynthetic process
0.42	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.41	GO:0010468	regulation of gene expression
0.36	GO:0036211	protein modification process
0.36	GO:0010029	regulation of seed germination
0.36	GO:0044267	cellular protein metabolic process
0.35	GO:0055114	oxidation-reduction process
0.35	GO:0007017	microtubule-based process
0.35	GO:0008104	protein localization
0.35	GO:0016569	covalent chromatin modification

0.43	GO:0003700	DNA binding transcription factor activity
0.43	GO:0003676	nucleic acid binding
0.37	GO:0008270	zinc ion binding
0.36	GO:0016787	hydrolase activity
0.36	GO:0016491	oxidoreductase activity
0.36	GO:0140096	catalytic activity, acting on a protein
0.36	GO:0030248	cellulose binding
0.35	GO:0005515	protein binding
0.35	GO:0016278	lysine N-methyltransferase activity
0.34	GO:0030554	adenyl nucleotide binding

0.36	GO:0005634	nucleus
0.36	GO:1990234	transferase complex
0.35	GO:0070013	intracellular organelle lumen
0.35	GO:0005576	extracellular region
0.35	GO:0044446	intracellular organelle part
0.34	GO:0005856	cytoskeleton
0.34	GO:0043234	protein complex
0.33	GO:0099512	supramolecular fiber
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.36

GO:0016787

tr|T1FUH0|T1FUH0_HELRO
Glutathione peroxidase
Search

0.45	Phospholipid hydroperoxide glutathione peroxidase, mitochondrial

0.71	GO:0006979	response to oxidative stress
0.69	GO:0098869	cellular oxidant detoxification
0.52	GO:0055114	oxidation-reduction process
0.42	GO:0110075	regulation of ferroptosis
0.40	GO:0007283	spermatogenesis
0.39	GO:0043069	negative regulation of programmed cell death
0.38	GO:0007275	multicellular organism development
0.37	GO:0051258	protein polymerization
0.35	GO:0006325	chromatin organization
0.35	GO:0032355	response to estradiol

0.79	GO:0004602	glutathione peroxidase activity
0.42	GO:0047066	phospholipid-hydroperoxide glutathione peroxidase activity
0.37	GO:0042802	identical protein binding
0.35	GO:0008430	selenium binding
0.32	GO:0016740	transferase activity

0.37	GO:0005739	mitochondrion
0.37	GO:0044428	nuclear part
0.36	GO:0031974	membrane-enclosed lumen
0.36	GO:0070062	extracellular exosome
0.36	GO:0005829	cytosol
0.35	GO:0012505	endomembrane system
0.35	GO:0043234	protein complex
0.34	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.79

EC:1.11.1.9

GO:0004602

tr|T1FUH1|T1FUH1_HELRO
Receptor protein serine/threonine kinase
Search

0.37	Receptor protein serine/threonine kinase

0.80	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
0.66	GO:0023014	signal transduction by protein phosphorylation
0.57	GO:1901163	regulation of trophoblast cell migration
0.51	GO:0006915	apoptotic process
0.50	GO:0032927	positive regulation of activin receptor signaling pathway
0.50	GO:0045648	positive regulation of erythrocyte differentiation
0.49	GO:0001942	hair follicle development
0.48	GO:1901383	negative regulation of chorionic trophoblast cell proliferation
0.48	GO:0010604	positive regulation of macromolecule metabolic process
0.48	GO:0018107	peptidyl-threonine phosphorylation

0.82	GO:0004675	transmembrane receptor protein serine/threonine kinase activity
0.79	GO:0004702	signal transducer, downstream of receptor, with serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0019838	growth factor binding
0.51	GO:0034711	inhibin binding
0.50	GO:0048185	activin binding
0.49	GO:0046332	SMAD binding

0.57	GO:0048179	activin receptor complex
0.45	GO:0009986	cell surface
0.43	GO:0005829	cytosol
0.35	GO:0070062	extracellular exosome

0.82

GO:0004675

tr|T1FUH2|T1FUH2_HELRO
Uncharacterized protein
Search

0.45	GO:0009788	negative regulation of abscisic acid-activated signaling pathway
0.45	GO:0016567	protein ubiquitination
0.44	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.41	GO:0010200	response to chitin
0.40	GO:0046686	response to cadmium ion
0.39	GO:0010738	regulation of protein kinase A signaling
0.39	GO:0000266	mitochondrial fission
0.39	GO:0035329	hippo signaling
0.38	GO:0043326	chemotaxis to folate
0.38	GO:0060176	regulation of aggregation involved in sorocarp development

0.48	GO:0016874	ligase activity
0.45	GO:0004842	ubiquitin-protein transferase activity
0.43	GO:0061659	ubiquitin-like protein ligase activity
0.43	GO:0008270	zinc ion binding
0.39	GO:0001871	pattern binding
0.37	GO:0030246	carbohydrate binding
0.37	GO:0000988	transcription factor activity, protein binding
0.36	GO:0004402	histone acetyltransferase activity
0.36	GO:0004672	protein kinase activity
0.35	GO:0005319	lipid transporter activity

0.40	GO:0005829	cytosol
0.39	GO:0005634	nucleus
0.37	GO:0005881	cytoplasmic microtubule
0.36	GO:0005815	microtubule organizing center
0.30	GO:0016020	membrane

0.48	EC:6	GO:0016874
0.45	KEGG:R03876	GO:0004842

tr|T1FUH3|T1FUH3_HELRO
Uncharacterized protein
Search

0.50	GO:0016573	histone acetylation
0.45	GO:1903506	regulation of nucleic acid-templated transcription
0.45	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.45	GO:0010468	regulation of gene expression
0.42	GO:0006511	ubiquitin-dependent protein catabolic process
0.40	GO:0006438	valyl-tRNA aminoacylation
0.38	GO:0048856	anatomical structure development
0.37	GO:0106074	aminoacyl-tRNA metabolism involved in translational fidelity
0.37	GO:0051703	intraspecies interaction between organisms
0.37	GO:0032501	multicellular organismal process

0.51	GO:0004402	histone acetyltransferase activity
0.47	GO:0003700	DNA binding transcription factor activity
0.40	GO:0004832	valine-tRNA ligase activity
0.38	GO:0017076	purine nucleotide binding
0.38	GO:0097367	carbohydrate derivative binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0008144	drug binding
0.37	GO:0002161	aminoacyl-tRNA editing activity
0.36	GO:0003676	nucleic acid binding
0.36	GO:0004672	protein kinase activity

0.45	GO:0008540	proteasome regulatory particle, base subcomplex
0.39	GO:0005634	nucleus
0.36	GO:0005765	lysosomal membrane
0.35	GO:0005829	cytosol
0.34	GO:0017053	transcriptional repressor complex
0.34	GO:0048786	presynaptic active zone
0.34	GO:0000428	DNA-directed RNA polymerase complex
0.33	GO:0005938	cell cortex
0.33	GO:0005856	cytoskeleton
0.33	GO:0070013	intracellular organelle lumen

0.51	EC:2.3.1.48	GO:0004402
0.40	KEGG:R03665	GO:0004832

tr|T1FUH4|T1FUH4_HELRO
Uncharacterized protein
Search

0.41	GO:0036211	protein modification process
0.40	GO:0044267	cellular protein metabolic process
0.39	GO:0065007	biological regulation
0.38	GO:0016310	phosphorylation
0.37	GO:0016192	vesicle-mediated transport
0.37	GO:0033036	macromolecule localization
0.37	GO:0016070	RNA metabolic process
0.37	GO:0006508	proteolysis
0.37	GO:0098662	inorganic cation transmembrane transport
0.36	GO:0046907	intracellular transport

0.41	GO:1990380	Lys48-specific deubiquitinase activity
0.40	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.39	GO:0140110	transcription regulator activity
0.38	GO:0016301	kinase activity
0.38	GO:0030554	adenyl nucleotide binding
0.38	GO:0015299	solute:proton antiporter activity
0.38	GO:0097367	carbohydrate derivative binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0003676	nucleic acid binding
0.38	GO:0005086	ARF guanyl-nucleotide exchange factor activity

0.40	GO:0005634	nucleus
0.40	GO:0030124	AP-4 adaptor complex
0.36	GO:0070013	intracellular organelle lumen
0.36	GO:0044446	intracellular organelle part
0.35	GO:0043232	intracellular non-membrane-bounded organelle
0.34	GO:0005667	transcription factor complex
0.34	GO:0030681	multimeric ribonuclease P complex
0.34	GO:0005576	extracellular region
0.34	GO:0020011	apicoplast
0.33	GO:0033061	DNA recombinase mediator complex

0.38	EC:2.7.1	GO:0016773
0.36	KEGG:R03876	GO:0004842

tr|T1FUH5|T1FUH5_HELRO
Uncharacterized protein
Search

0.58	GO:0006367	transcription initiation from RNA polymerase II promoter
0.53	GO:0006413	translational initiation
0.46	GO:0044085	cellular component biogenesis
0.44	GO:0043933	macromolecular complex subunit organization
0.43	GO:0006996	organelle organization
0.40	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound
0.40	GO:0007291	sperm individualization
0.40	GO:0016072	rRNA metabolic process
0.40	GO:0031445	regulation of heterochromatin assembly
0.39	GO:0030317	flagellated sperm motility

0.54	GO:0003743	translation initiation factor activity
0.43	GO:0019901	protein kinase binding
0.40	GO:0016887	ATPase activity
0.39	GO:0008144	drug binding
0.39	GO:0030554	adenyl nucleotide binding
0.39	GO:0043168	anion binding
0.39	GO:0097367	carbohydrate derivative binding
0.39	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.38	GO:0051082	unfolded protein binding
0.38	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding

0.47	GO:0005634	nucleus
0.43	GO:0030684	preribosome
0.41	GO:0070013	intracellular organelle lumen
0.40	GO:0044446	intracellular organelle part
0.39	GO:0043232	intracellular non-membrane-bounded organelle
0.38	GO:0120114	Sm-like protein family complex
0.37	GO:0043234	protein complex
0.37	GO:0005732	small nucleolar ribonucleoprotein complex
0.37	GO:0044444	cytoplasmic part
0.36	GO:0012505	endomembrane system

0.40

GO:0016887

tr|T1FUH6|T1FUH6_HELRO
Uncharacterized protein
Search

0.48	GO:0033674	positive regulation of kinase activity
0.47	GO:0045859	regulation of protein kinase activity
0.47	GO:0007018	microtubule-based movement
0.46	GO:0006417	regulation of translation
0.43	GO:0033554	cellular response to stress
0.43	GO:0036211	protein modification process
0.41	GO:0044267	cellular protein metabolic process
0.38	GO:0016310	phosphorylation
0.37	GO:0006508	proteolysis
0.35	GO:0006886	intracellular protein transport

0.48	GO:0019887	protein kinase regulator activity
0.48	GO:0019901	protein kinase binding
0.47	GO:0003777	microtubule motor activity
0.47	GO:0043022	ribosome binding
0.43	GO:0140096	catalytic activity, acting on a protein
0.39	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.39	GO:0016874	ligase activity
0.39	GO:0016301	kinase activity
0.38	GO:0097367	carbohydrate derivative binding
0.38	GO:0008144	drug binding

0.44	GO:0005634	nucleus
0.36	GO:0070701	mucus layer
0.35	GO:0031012	extracellular matrix
0.35	GO:0005929	cilium
0.34	GO:0043233	organelle lumen
0.33	GO:0005737	cytoplasm
0.33	GO:0043234	protein complex
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.39

GO:0016773

tr|T1FUH7|T1FUH7_HELRO
Diphthine--ammonia ligase
Search

0.37	Diphthine--ammonia ligase

0.62	GO:0017182	peptidyl-diphthamide metabolic process
0.62	GO:1900247	regulation of cytoplasmic translational elongation
0.41	GO:0009058	biosynthetic process
0.37	GO:1903955	positive regulation of protein targeting to mitochondrion
0.36	GO:0031647	regulation of protein stability
0.36	GO:0051321	meiotic cell cycle

0.68	GO:0017178	diphthine-ammonia ligase activity
0.49	GO:0032559	adenyl ribonucleotide binding
0.48	GO:0008144	drug binding
0.48	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0016787	hydrolase activity

0.35	GO:0005634	nucleus
0.35	GO:0005829	cytosol
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0043232	intracellular non-membrane-bounded organelle
0.33	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.68	EC:6.3.1.14	GO:0017178
0.68	KEGG:R03613	GO:0017178

tr|T1FUH8|T1FUH8_HELRO
Uncharacterized protein
Search

0.74	GO:0007018	microtubule-based movement
0.47	GO:0010923	negative regulation of phosphatase activity
0.41	GO:0051641	cellular localization
0.38	GO:0098927	vesicle-mediated transport between endosomal compartments
0.37	GO:0048803	imaginal disc-derived male genitalia morphogenesis
0.37	GO:0071907	determination of digestive tract left/right asymmetry
0.36	GO:0007498	mesoderm development
0.36	GO:0030900	forebrain development

0.74	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.74	GO:0003779	actin binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0019904	protein domain specific binding
0.38	GO:0030898	actin-dependent ATPase activity
0.37	GO:0000146	microfilament motor activity

0.77	GO:0016459	myosin complex
0.46	GO:0005903	brush border
0.45	GO:0043209	myelin sheath
0.45	GO:0043025	neuronal cell body
0.44	GO:0030424	axon
0.38	GO:0097440	apical dendrite
0.37	GO:0016323	basolateral plasma membrane
0.37	GO:0005790	smooth endoplasmic reticulum
0.37	GO:0032589	neuron projection membrane
0.36	GO:0031410	cytoplasmic vesicle

tr|T1FUH9|T1FUH9_HELRO
Uncharacterized protein
Search

tr|T1FUI0|T1FUI0_HELRO
Uncharacterized protein
Search

tr|T1FUI1|T1FUI1_HELRO
Uncharacterized protein
Search

tr|T1FUI2|T1FUI2_HELRO
Uncharacterized protein
Search

tr|T1FUI3|T1FUI3_HELRO
Uncharacterized protein
Search

tr|T1FUI4|T1FUI4_HELRO
Uncharacterized protein
Search

tr|T1FUI5|T1FUI5_HELRO
Uncharacterized protein
Search

tr|T1FUI6|T1FUI6_HELRO
Uncharacterized protein
Search

tr|T1FUI7|T1FUI7_HELRO
Putative Activin/Myostatin/TGF-beta-class TGF-beta signal molecule
Search

0.64	Myostatin 1

0.76

GO:0010469

regulation of receptor activity

0.78

GO:0008083

growth factor activity

0.66

GO:0005576

extracellular region

tr|T1FUI8|T1FUI8_HELRO
Uncharacterized protein
Search

0.43	GO:0070701	mucus layer
0.30	GO:0044425	membrane part

tr|T1FUI9|T1FUI9_HELRO
Uncharacterized protein
Search

tr|T1FUJ0|T1FUJ0_HELRO
Uncharacterized protein
Search

0.36	GO:0006511	ubiquitin-dependent protein catabolic process
0.34	GO:0097659	nucleic acid-templated transcription
0.33	GO:0010467	gene expression
0.33	GO:0034645	cellular macromolecule biosynthetic process

0.35	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.35	GO:0008270	zinc ion binding
0.34	GO:0003677	DNA binding

0.34	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.35

GO:0003899

tr|T1FUJ1|T1FUJ1_HELRO
Uncharacterized protein
Search

tr|T1FUJ2|T1FUJ2_HELRO
Uncharacterized protein
Search

tr|T1FUJ3|T1FUJ3_HELRO
Uncharacterized protein
Search

0.48	GO:0035277	spiracle morphogenesis, open tracheal system
0.48	GO:0060429	epithelium development
0.48	GO:0035120	post-embryonic appendage morphogenesis
0.48	GO:0035114	imaginal disc-derived appendage morphogenesis
0.47	GO:0035025	positive regulation of Rho protein signal transduction
0.47	GO:0048563	post-embryonic animal organ morphogenesis
0.47	GO:0048707	instar larval or pupal morphogenesis
0.47	GO:0007552	metamorphosis
0.46	GO:0035239	tube morphogenesis
0.46	GO:0048667	cell morphogenesis involved in neuron differentiation

0.44	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.44	GO:0140110	transcription regulator activity
0.42	GO:0003677	DNA binding
0.40	GO:0008270	zinc ion binding
0.40	GO:0046983	protein dimerization activity
0.39	GO:0140096	catalytic activity, acting on a protein
0.38	GO:0097367	carbohydrate derivative binding
0.37	GO:0017171	serine hydrolase activity
0.37	GO:0001102	RNA polymerase II activating transcription factor binding
0.37	GO:0008144	drug binding

0.48	GO:0045179	apical cortex
0.47	GO:0005634	nucleus
0.43	GO:1990234	transferase complex
0.42	GO:1905368	peptidase complex
0.42	GO:0070013	intracellular organelle lumen
0.41	GO:0005667	transcription factor complex
0.40	GO:0044446	intracellular organelle part
0.39	GO:0098536	deuterosome
0.37	GO:0005694	chromosome
0.36	GO:0015630	microtubule cytoskeleton

0.34