Queries 16001 to 17000

GO:0004518

tr|T1FNU5|T1FNU5_HELRO
Uncharacterized protein
Search

0.52	Adrenodoxin protein, mitochondrial

0.61	GO:0022900	electron transport chain
0.42	GO:0045966	positive regulation of ecdysteroid metabolic process
0.42	GO:0007554	regulation of ecdysteroid biosynthetic process
0.41	GO:0090031	positive regulation of steroid hormone biosynthetic process
0.41	GO:0035073	pupariation
0.34	GO:0006700	C21-steroid hormone biosynthetic process
0.34	GO:0016125	sterol metabolic process
0.32	GO:0044281	small molecule metabolic process

0.71	GO:0051537	2 iron, 2 sulfur cluster binding
0.62	GO:0009055	electron transfer activity
0.34	GO:0046872	metal ion binding
0.33	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.36	GO:0005759	mitochondrial matrix
0.33	GO:0019013	viral nucleocapsid
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0031224	intrinsic component of membrane

tr|T1FNU6|T1FNU6_HELRO
Uncharacterized protein
Search

GTPBP6

0.80	GTP-binding protein 6

0.33	GO:0015074	DNA integration
0.33	GO:0032259	methylation
0.32	GO:0016310	phosphorylation

0.66	GO:0001883	purine nucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.65	GO:0032549	ribonucleoside binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0003924	GTPase activity
0.41	GO:0043022	ribosome binding
0.33	GO:0008168	methyltransferase activity
0.33	GO:0016301	kinase activity
0.32	GO:0046872	metal ion binding

0.38	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0008168

tr|T1FNU7|T1FNU7_HELRO
Uncharacterized protein
Search

tr|T1FNU8|T1FNU8_HELRO
Deoxyhypusine hydroxylase
Search

DOHH

0.73	Deoxyhypusine hydroxylase

0.81	GO:0008612	peptidyl-lysine modification to peptidyl-hypusine
0.52	GO:0055114	oxidation-reduction process
0.41	GO:0006915	apoptotic process
0.38	GO:0001522	pseudouridine synthesis

0.85	GO:0019135	deoxyhypusine monooxygenase activity
0.51	GO:0046872	metal ion binding
0.38	GO:0009982	pseudouridine synthase activity
0.35	GO:0003723	RNA binding

0.41	GO:0005761	mitochondrial ribosome
0.39	GO:0015935	small ribosomal subunit
0.30	GO:0031224	intrinsic component of membrane

0.85

EC:1.14.99.29

GO:0019135

tr|T1FNU9|T1FNU9_HELRO
Uncharacterized protein
Search

0.38	GO:1902476	chloride transmembrane transport
0.37	GO:0042357	thiamine diphosphate metabolic process
0.36	GO:0072528	pyrimidine-containing compound biosynthetic process
0.36	GO:0044272	sulfur compound biosynthetic process
0.36	GO:0009108	coenzyme biosynthetic process
0.36	GO:0032259	methylation
0.35	GO:0090407	organophosphate biosynthetic process
0.35	GO:0006508	proteolysis
0.35	GO:0016310	phosphorylation
0.34	GO:0019438	aromatic compound biosynthetic process

0.39	GO:0004788	thiamine diphosphokinase activity
0.38	GO:0030975	thiamine binding
0.38	GO:0005247	voltage-gated chloride channel activity
0.36	GO:0004252	serine-type endopeptidase activity
0.36	GO:0008168	methyltransferase activity
0.35	GO:0016301	kinase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0016020

membrane

0.39

EC:2.7.6.2

GO:0004788

tr|T1FNV0|T1FNV0_HELRO
Uncharacterized protein
Search

0.37	Carbonic anhydrase VII

0.69	GO:0006730	one-carbon metabolic process
0.42	GO:0035335	peptidyl-tyrosine dephosphorylation
0.38	GO:0015701	bicarbonate transport
0.36	GO:2000021	regulation of ion homeostasis
0.35	GO:0006885	regulation of pH
0.35	GO:2001225	regulation of chloride transport
0.35	GO:0032230	positive regulation of synaptic transmission, GABAergic
0.35	GO:0035810	positive regulation of urine volume
0.35	GO:0044062	regulation of excretion
0.35	GO:0098801	regulation of renal system process

0.74	GO:0004089	carbonate dehydratase activity
0.60	GO:0008270	zinc ion binding
0.42	GO:0004725	protein tyrosine phosphatase activity

0.42	GO:0031225	anchored component of membrane
0.39	GO:0031233	intrinsic component of external side of plasma membrane
0.38	GO:0016324	apical plasma membrane
0.38	GO:0031526	brush border membrane
0.38	GO:0030667	secretory granule membrane
0.38	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.38	GO:0005791	rough endoplasmic reticulum
0.38	GO:0070062	extracellular exosome
0.37	GO:0005802	trans-Golgi network
0.37	GO:0048471	perinuclear region of cytoplasm

0.74

EC:4.2.1.1

GO:0004089

tr|T1FNV1|T1FNV1_HELRO
Uncharacterized protein
Search

RGP1

0.94	Retrograde Golgi transport protein RGP1

0.78	GO:0042147	retrograde transport, endosome to Golgi
0.76	GO:1903363	negative regulation of cellular protein catabolic process
0.68	GO:0043547	positive regulation of GTPase activity
0.39	GO:0007165	signal transduction
0.36	GO:0006508	proteolysis

0.81	GO:0017112	Rab guanyl-nucleotide exchange factor activity
0.37	GO:0004252	serine-type endopeptidase activity

0.85	GO:0034066	RIC1-RGP1 guanyl-nucleotide exchange factor complex
0.66	GO:0005829	cytosol
0.57	GO:0000139	Golgi membrane
0.51	GO:0005886	plasma membrane
0.38	GO:0005802	trans-Golgi network
0.30	GO:0031224	intrinsic component of membrane

0.37

GO:0004252

tr|T1FNV2|T1FNV2_HELRO
Uncharacterized protein
Search

0.60	GRIM-19 superfamily protein, accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase, involved in animal cell death programs

0.45	GO:0097191	extrinsic apoptotic signaling pathway
0.44	GO:0035458	cellular response to interferon-beta
0.43	GO:0071300	cellular response to retinoic acid
0.43	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway
0.43	GO:0045039	protein import into mitochondrial inner membrane
0.43	GO:0032981	mitochondrial respiratory chain complex I assembly
0.43	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.42	GO:0030308	negative regulation of cell growth
0.42	GO:0045732	positive regulation of protein catabolic process
0.40	GO:0072593	reactive oxygen species metabolic process

0.40	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0008144	drug binding
0.33	GO:0005515	protein binding
0.32	GO:0003677	DNA binding

0.42	GO:0005747	mitochondrial respiratory chain complex I
0.39	GO:0005654	nucleoplasm
0.37	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.40

EC:1.6.5.3

GO:0008137

tr|T1FNV3|T1FNV3_HELRO
Uncharacterized protein
Search

0.49	Thyroid receptor-interacting protein 13

0.41	GO:0051598	meiotic recombination checkpoint
0.36	GO:0007131	reciprocal meiotic recombination
0.35	GO:0007144	female meiosis I
0.35	GO:0001556	oocyte maturation
0.35	GO:0007141	male meiosis I
0.35	GO:0007130	synaptonemal complex assembly
0.34	GO:0007286	spermatid development
0.34	GO:0007094	mitotic spindle assembly checkpoint
0.34	GO:0042138	meiotic DNA double-strand break formation
0.34	GO:0051013	microtubule severing

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0016787	hydrolase activity
0.34	GO:0042802	identical protein binding
0.33	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors
0.32	GO:0140096	catalytic activity, acting on a protein

0.35	GO:0001673	male germ cell nucleus
0.33	GO:0005694	chromosome
0.30	GO:0016020	membrane

0.36

GO:0016787

tr|T1FNV4|T1FNV4_HELRO
Pyrroline-5-carboxylate reductase
Search

PROC

0.41	Pyrroline-5-carboxylate reductase

0.75	GO:0006561	proline biosynthetic process
0.58	GO:0017144	drug metabolic process
0.53	GO:0055114	oxidation-reduction process

0.79

GO:0004735

pyrroline-5-carboxylate reductase activity

0.48	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.79

EC:1.5.1.2

GO:0004735

tr|T1FNV5|T1FNV5_HELRO
Uncharacterized protein
Search

CNOT11

0.78	CCR4-NOT transcription complex subunit

0.38	GO:0006417	regulation of translation
0.37	GO:0031047	gene silencing by RNA
0.36	GO:0006402	mRNA catabolic process
0.35	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
0.35	GO:0034249	negative regulation of cellular amide metabolic process
0.35	GO:0032269	negative regulation of cellular protein metabolic process
0.35	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
0.34	GO:0008283	cell proliferation
0.34	GO:0006351	transcription, DNA-templated
0.34	GO:1903506	regulation of nucleic acid-templated transcription

0.33	GO:0005515	protein binding
0.32	GO:0046872	metal ion binding

0.82	GO:0030014	CCR4-NOT complex
0.35	GO:0005634	nucleus
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

tr|T1FNV6|T1FNV6_HELRO
Uncharacterized protein
Search

0.78	6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase short form

0.83	GO:0006003	fructose 2,6-bisphosphate metabolic process
0.83	GO:0006000	fructose metabolic process
0.74	GO:0046835	carbohydrate phosphorylation
0.37	GO:0016311	dephosphorylation
0.36	GO:0006757	ATP generation from ADP
0.36	GO:0006090	pyruvate metabolic process
0.36	GO:0016052	carbohydrate catabolic process
0.36	GO:0019362	pyridine nucleotide metabolic process

0.84	GO:0003873	6-phosphofructo-2-kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity
0.34	GO:0042802	identical protein binding

0.35	GO:0043540	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex
0.30	GO:0016020	membrane

0.84	EC:2.7.1.105	GO:0003873
0.84	KEGG:R02732	GO:0003873

tr|T1FNV7|T1FNV7_HELRO
ATPase ASNA1 homolog
Search

ASNA1

0.83	Arsenical pump-driving ATPase (Fragment)

0.80	GO:0045048	protein insertion into ER membrane
0.41	GO:0007416	synapse assembly
0.35	GO:0036498	IRE1-mediated unfolded protein response
0.34	GO:0015698	inorganic anion transport
0.34	GO:0071722	detoxification of arsenic-containing substance
0.34	GO:1901684	arsenate ion transmembrane transport
0.34	GO:0050482	arachidonic acid secretion
0.33	GO:0016042	lipid catabolic process
0.33	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.33	GO:0006644	phospholipid metabolic process

0.61	GO:0016887	ATPase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0046872	metal ion binding
0.35	GO:0015105	arsenite transmembrane transporter activity
0.34	GO:1901683	arsenate ion transmembrane transporter activity
0.34	GO:0004623	phospholipase A2 activity
0.33	GO:0022853	active ion transmembrane transporter activity
0.33	GO:0015291	secondary active transmembrane transporter activity

0.70	GO:0005783	endoplasmic reticulum
0.46	GO:0005730	nucleolus
0.36	GO:0070062	extracellular exosome
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.61

GO:0016887

tr|T1FNV8|T1FNV8_HELRO
Uncharacterized protein
Search

0.52	Mitochondrial thiamine pyrophosphate carrier

0.54	GO:0055085	transmembrane transport
0.42	GO:0080121	AMP transport
0.40	GO:0015866	ADP transport
0.40	GO:0015867	ATP transport
0.40	GO:0006839	mitochondrial transport
0.39	GO:0015744	succinate transport
0.37	GO:0045117	azole transport
0.36	GO:0009060	aerobic respiration
0.36	GO:0072348	sulfur compound transport
0.36	GO:0051180	vitamin transport

0.42	GO:0080122	AMP transmembrane transporter activity
0.40	GO:0015217	ADP transmembrane transporter activity
0.40	GO:0005347	ATP transmembrane transporter activity
0.39	GO:0015141	succinate transmembrane transporter activity
0.37	GO:1901474	azole transmembrane transporter activity
0.36	GO:0090482	vitamin transmembrane transporter activity
0.36	GO:1901682	sulfur compound transmembrane transporter activity
0.33	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.33	GO:0004725	protein tyrosine phosphatase activity
0.33	GO:0005337	nucleoside transmembrane transporter activity

0.40	GO:0031090	organelle membrane
0.40	GO:0005739	mitochondrion
0.39	GO:0044446	intracellular organelle part
0.38	GO:0005773	vacuole
0.38	GO:0098805	whole membrane
0.38	GO:0031975	envelope
0.37	GO:0009536	plastid
0.34	GO:0045111	intermediate filament cytoskeleton
0.33	GO:0099512	supramolecular fiber
0.33	GO:0009505	plant-type cell wall

0.33

EC:3.1.3

GO:0008138

tr|T1FNV9|T1FNV9_HELRO
GMP reductase
Search

GMPR

0.57	GMP reductase

0.67	GO:0006144	purine nucleobase metabolic process
0.59	GO:0006163	purine nucleotide metabolic process
0.53	GO:0055114	oxidation-reduction process
0.36	GO:0072522	purine-containing compound biosynthetic process
0.36	GO:0009409	response to cold
0.36	GO:0009165	nucleotide biosynthetic process
0.33	GO:0043094	cellular metabolic compound salvage

0.82	GO:0003920	GMP reductase activity
0.52	GO:0046872	metal ion binding
0.38	GO:0003938	IMP dehydrogenase activity

0.81	GO:1902560	GMP reductase complex
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.82	EC:1.7.1.7	GO:0003920
0.82	KEGG:R01134	GO:0003920

tr|T1FNW0|T1FNW0_HELRO
Uncharacterized protein
Search

ERG28

0.97	Ergosterol biosynthesis 28 homolog

0.47	GO:0016126	sterol biosynthetic process
0.47	GO:0008204	ergosterol metabolic process
0.47	GO:0044108	cellular alcohol biosynthetic process
0.47	GO:0016129	phytosteroid biosynthetic process
0.47	GO:0097384	cellular lipid biosynthetic process
0.47	GO:1902653	secondary alcohol biosynthetic process

0.47

GO:0030674

protein binding, bridging

0.55	GO:0030133	transport vesicle
0.45	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1FNW1|T1FNW1_HELRO
Uncharacterized protein
Search

MNAT1

0.74	MNAT CDK-activating kinase assembly factor 1

0.85	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity
0.73	GO:0006289	nucleotide-excision repair
0.52	GO:0007512	adult heart development
0.51	GO:0021591	ventricular system development
0.50	GO:0016310	phosphorylation
0.50	GO:0051592	response to calcium ion
0.47	GO:0006366	transcription by RNA polymerase II
0.47	GO:0006357	regulation of transcription by RNA polymerase II
0.45	GO:0045893	positive regulation of transcription, DNA-templated
0.43	GO:0036211	protein modification process

0.85	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity
0.54	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity
0.50	GO:0047485	protein N-terminus binding
0.44	GO:0008094	DNA-dependent ATPase activity
0.44	GO:0004693	cyclin-dependent protein serine/threonine kinase activity
0.34	GO:0046872	metal ion binding
0.34	GO:0000990	transcription factor activity, core RNA polymerase binding
0.34	GO:0016874	ligase activity

0.83	GO:0005675	holo TFIIH complex
0.44	GO:0005829	cytosol
0.35	GO:0042585	germinal vesicle
0.33	GO:0005694	chromosome

0.54

EC:2.7.11.23

GO:0008353

tr|T1FNW2|T1FNW2_HELRO
Elongation factor Tu
Search

0.45	Elongation factor Tu

0.69	GO:0006414	translational elongation
0.42	GO:0007030	Golgi organization
0.42	GO:0008283	cell proliferation
0.41	GO:0000278	mitotic cell cycle
0.34	GO:0007017	microtubule-based process
0.34	GO:0007010	cytoskeleton organization
0.34	GO:0032543	mitochondrial translation
0.34	GO:0051258	protein polymerization
0.34	GO:0097435	supramolecular fiber organization
0.33	GO:0006413	translational initiation

0.69	GO:0003746	translation elongation factor activity
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0043015	gamma-tubulin binding
0.34	GO:0005484	SNAP receptor activity
0.34	GO:0005200	structural constituent of cytoskeleton
0.33	GO:0003743	translation initiation factor activity

0.44	GO:0005622	intracellular
0.38	GO:0043209	myelin sheath
0.36	GO:0009295	nucleoid
0.35	GO:0043227	membrane-bounded organelle
0.35	GO:0044422	organelle part
0.35	GO:0031974	membrane-enclosed lumen
0.35	GO:0043228	non-membrane-bounded organelle
0.35	GO:0031975	envelope
0.33	GO:0099512	supramolecular fiber
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0016779

tr|T1FNW3|T1FNW3_HELRO
Uncharacterized protein
Search

0.84	Lipid phosphate phosphohydrolase 3

0.63	GO:0030111	regulation of Wnt signaling pathway
0.61	GO:0016311	dephosphorylation
0.56	GO:0006629	lipid metabolic process
0.53	GO:1902068	regulation of sphingolipid mediated signaling pathway
0.52	GO:0060020	Bergmann glial cell differentiation
0.51	GO:0060070	canonical Wnt signaling pathway
0.50	GO:0001702	gastrulation with mouth forming second
0.49	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
0.49	GO:0051091	positive regulation of DNA binding transcription factor activity
0.48	GO:0019637	organophosphate metabolic process

0.71	GO:0042577	lipid phosphatase activity
0.60	GO:0008195	phosphatidate phosphatase activity
0.54	GO:0042392	sphingosine-1-phosphate phosphatase activity
0.50	GO:0005178	integrin binding
0.37	GO:0005319	lipid transporter activity
0.33	GO:0004721	phosphoprotein phosphatase activity
0.33	GO:0004386	helicase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0008144	drug binding

0.46	GO:0005886	plasma membrane
0.37	GO:0045177	apical part of cell
0.36	GO:0070062	extracellular exosome
0.36	GO:0012505	endomembrane system
0.35	GO:0031984	organelle subcompartment
0.34	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0044444	cytoplasmic part
0.34	GO:0005912	adherens junction
0.30	GO:0016021	integral component of membrane

0.60

EC:3.1.3.4

GO:0008195

tr|T1FNW4|T1FNW4_HELRO
Uncharacterized protein
Search

PRPF19

0.74	Pre-mRNA-processing factor

0.71	GO:0016567	protein ubiquitination
0.52	GO:0048711	positive regulation of astrocyte differentiation
0.51	GO:0048026	positive regulation of mRNA splicing, via spliceosome
0.51	GO:0072422	signal transduction involved in DNA damage checkpoint
0.51	GO:0000244	spliceosomal tri-snRNP complex assembly
0.50	GO:0001833	inner cell mass cell proliferation
0.49	GO:0045665	negative regulation of neuron differentiation
0.49	GO:0000349	generation of catalytic spliceosome for first transesterification step
0.49	GO:0000245	spliceosomal complex assembly
0.49	GO:0006303	double-strand break repair via nonhomologous end joining

0.72	GO:0004842	ubiquitin-protein transferase activity
0.48	GO:0061659	ubiquitin-like protein ligase activity
0.46	GO:0042802	identical protein binding
0.36	GO:0003743	translation initiation factor activity

0.54	GO:0000974	Prp19 complex
0.52	GO:0005684	U2-type spliceosomal complex
0.51	GO:0005662	DNA replication factor A complex
0.50	GO:0035861	site of double-strand break
0.49	GO:0005811	lipid droplet
0.49	GO:0071013	catalytic step 2 spliceosome
0.49	GO:0016607	nuclear speck
0.48	GO:0071012	catalytic step 1 spliceosome
0.38	GO:0005819	spindle
0.37	GO:0005737	cytoplasm

0.72

GO:0004842

tr|T1FNW5|T1FNW5_HELRO
Uncharacterized protein
Search

0.50	AN1-type zinc finger protein 5

0.52	GO:0010761	fibroblast migration
0.52	GO:0003016	respiratory system process
0.51	GO:0048745	smooth muscle tissue development
0.51	GO:0048008	platelet-derived growth factor receptor signaling pathway
0.51	GO:0060324	face development
0.49	GO:0048705	skeletal system morphogenesis
0.48	GO:0001944	vasculature development
0.47	GO:0001701	in utero embryonic development

0.63	GO:0008270	zinc ion binding
0.54	GO:0003677	DNA binding
0.33	GO:0005515	protein binding

0.33

GO:0005737

cytoplasm

tr|T1FNW6|T1FNW6_HELRO
S-adenosylmethionine decarboxylase proenzyme
Search

AMD1

0.54	S-adenosylmethionine decarboxylase proenzyme

0.85	GO:0006597	spermine biosynthetic process
0.78	GO:0008295	spermidine biosynthetic process
0.73	GO:0006557	S-adenosylmethioninamine biosynthetic process
0.38	GO:0050829	defense response to Gram-negative bacterium
0.36	GO:0001701	in utero embryonic development
0.34	GO:0046500	S-adenosylmethionine metabolic process
0.33	GO:0016567	protein ubiquitination

0.82	GO:0004014	adenosylmethionine decarboxylase activity
0.46	GO:0019810	putrescine binding
0.33	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0005515	protein binding
0.33	GO:0008270	zinc ion binding

0.42	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.82	EC:4.1.1.50	GO:0004014
0.82	KEGG:R00178	GO:0004014

tr|T1FNW7|T1FNW7_HELRO
Uncharacterized protein
Search

CSNK1A1

0.72	Casein kinase 1 protein catalytic subunit

0.63	GO:0006468	protein phosphorylation
0.47	GO:0018209	peptidyl-serine modification
0.45	GO:0006909	phagocytosis
0.44	GO:0016055	Wnt signaling pathway
0.44	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.41	GO:0051128	regulation of cellular component organization
0.41	GO:0022603	regulation of anatomical structure morphogenesis
0.41	GO:1904424	regulation of GTP binding
0.40	GO:0045104	intermediate filament cytoskeleton organization
0.39	GO:0007030	Golgi organization

0.67	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0004610	phosphoacetylglucosamine mutase activity
0.34	GO:0005057	signal transducer activity, downstream of receptor
0.33	GO:0000287	magnesium ion binding

0.42	GO:0005813	centrosome
0.41	GO:0005634	nucleus
0.40	GO:0030877	beta-catenin destruction complex
0.40	GO:0045095	keratin filament
0.39	GO:0036064	ciliary basal body
0.39	GO:0005829	cytosol
0.37	GO:0031974	membrane-enclosed lumen
0.35	GO:0030529	intracellular ribonucleoprotein complex
0.34	GO:0000777	condensed chromosome kinetochore
0.34	GO:0000139	Golgi membrane

0.67	EC:2.7.11	GO:0004674
0.37	KEGG:R08193	GO:0004610

tr|T1FNW8|T1FNW8_HELRO
Uncharacterized protein
Search

MTPN

0.97	Myotrophin

0.85	GO:0014742	positive regulation of muscle hypertrophy
0.85	GO:0010611	regulation of cardiac muscle hypertrophy
0.85	GO:2000812	regulation of barbed-end actin filament capping
0.79	GO:0008361	regulation of cell size
0.57	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.56	GO:0030307	positive regulation of cell growth
0.53	GO:0021684	cerebellar granular layer formation
0.52	GO:0043403	skeletal muscle tissue regeneration
0.52	GO:0021533	cell differentiation in hindbrain
0.52	GO:0051247	positive regulation of protein metabolic process

0.43	GO:0043565	sequence-specific DNA binding
0.39	GO:0005515	protein binding

0.81	GO:0008290	F-actin capping protein complex
0.55	GO:0030424	axon
0.54	GO:0048471	perinuclear region of cytoplasm
0.49	GO:0005829	cytosol
0.47	GO:0005634	nucleus
0.44	GO:0070062	extracellular exosome

tr|T1FNW9|T1FNW9_HELRO
Uncharacterized protein
Search

0.65	N-terminal domain of NEFA-interacting nuclear protein NIP30

0.48	GO:0050819	negative regulation of coagulation
0.46	GO:0016578	histone deubiquitination
0.43	GO:0006511	ubiquitin-dependent protein catabolic process
0.39	GO:0032259	methylation

0.47	GO:0005544	calcium-dependent phospholipid binding
0.45	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.43	GO:0005509	calcium ion binding
0.39	GO:0008168	methyltransferase activity

0.45	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.39

GO:0008168

tr|T1FNX0|T1FNX0_HELRO
Uncharacterized protein
Search

ALDH2

0.38	aldehyde dehydrogenase, mitochondrial

0.53	GO:0055114	oxidation-reduction process
0.47	GO:0006081	cellular aldehyde metabolic process
0.40	GO:0010941	regulation of cell death
0.40	GO:0006068	ethanol catabolic process
0.39	GO:0021768	nucleus accumbens development
0.39	GO:0045471	response to ethanol
0.39	GO:0060166	olfactory pit development
0.39	GO:0070384	Harderian gland development
0.39	GO:0002072	optic cup morphogenesis involved in camera-type eye development
0.39	GO:0060013	righting reflex

0.69	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.38	GO:0070324	thyroid hormone binding
0.37	GO:0051287	NAD binding
0.37	GO:0042802	identical protein binding
0.36	GO:0046983	protein dimerization activity
0.34	GO:0043168	anion binding
0.33	GO:0004222	metalloendopeptidase activity
0.33	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors
0.33	GO:0004672	protein kinase activity
0.33	GO:0016853	isomerase activity

0.39	GO:0005739	mitochondrion
0.37	GO:0070013	intracellular organelle lumen
0.36	GO:0005829	cytosol
0.35	GO:0005634	nucleus
0.35	GO:0070062	extracellular exosome
0.35	GO:0044446	intracellular organelle part
0.34	GO:0000793	condensed chromosome
0.34	GO:0015630	microtubule cytoskeleton
0.34	GO:0005886	plasma membrane
0.33	GO:0032991	macromolecular complex

0.69

EC:1.2.1

GO:0016620

tr|T1FNX1|T1FNX1_HELRO
Uncharacterized protein
Search

0.66	Actin regulatory protein CAP-G

0.56	GO:0051017	actin filament bundle assembly
0.47	GO:0051693	actin filament capping
0.47	GO:0051014	actin filament severing
0.43	GO:0045010	actin nucleation
0.40	GO:2000012	regulation of auxin polar transport
0.40	GO:0009630	gravitropism
0.38	GO:0001558	regulation of cell growth
0.35	GO:0030043	actin filament fragmentation
0.34	GO:0030041	actin filament polymerization
0.33	GO:0009734	auxin-activated signaling pathway

0.78	GO:0051015	actin filament binding
0.41	GO:0005509	calcium ion binding
0.34	GO:0005544	calcium-dependent phospholipid binding
0.33	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity

0.39	GO:0032432	actin filament bundle
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.33	EC:3.2.1.113	GO:0004571
0.33	KEGG:R05982 KEGG:R06722	GO:0004571

tr|T1FNX2|T1FNX2_HELRO
Uncharacterized protein
Search

0.53	GO:1900264	positive regulation of DNA-directed DNA polymerase activity
0.40	GO:0006260	DNA replication
0.35	GO:0007049	cell cycle
0.32	GO:0055114	oxidation-reduction process
0.32	GO:0006629	lipid metabolic process

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0003689	DNA clamp loader activity
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0043142	single-stranded DNA-dependent ATPase activity
0.33	GO:0005515	protein binding
0.33	GO:0004386	helicase activity
0.32	GO:0016874	ligase activity
0.32	GO:0016491	oxidoreductase activity

0.50	GO:0031390	Ctf18 RFC-like complex
0.46	GO:0005654	nucleoplasm
0.45	GO:0005829	cytosol
0.43	GO:0005663	DNA replication factor C complex
0.30	GO:0016020	membrane

0.32

GO:0016874

tr|T1FNX3|T1FNX3_HELRO
Uncharacterized protein
Search

0.69	Vesicle (multivesicular body) trafficking 1

0.81	GO:0071985	multivesicular body sorting pathway
0.66	GO:0032781	positive regulation of ATPase activity
0.63	GO:0016197	endosomal transport
0.60	GO:0046755	viral budding

0.69	GO:0008022	protein C-terminus binding
0.66	GO:0001671	ATPase activator activity

0.73	GO:1990621	ESCRT IV complex
0.69	GO:0005771	multivesicular body
0.59	GO:0005654	nucleoplasm
0.58	GO:0005829	cytosol

tr|T1FNX4|T1FNX4_HELRO
Uncharacterized protein
Search

SLC25A42

0.89	Putative mitochondrial coenzyme a transporter

0.55	GO:0055085	transmembrane transport
0.47	GO:0080121	AMP transport
0.47	GO:0015880	coenzyme A transport
0.46	GO:0006839	mitochondrial transport
0.45	GO:0015866	ADP transport
0.41	GO:0015867	ATP transport
0.37	GO:0050829	defense response to Gram-negative bacterium
0.36	GO:0045089	positive regulation of innate immune response
0.34	GO:0007006	mitochondrial membrane organization
0.33	GO:0006468	protein phosphorylation

0.47	GO:0080122	AMP transmembrane transporter activity
0.47	GO:0071077	adenosine 3',5'-bisphosphate transmembrane transporter activity
0.45	GO:0015217	ADP transmembrane transporter activity
0.44	GO:0051185	coenzyme transmembrane transporter activity
0.43	GO:0043262	adenosine-diphosphatase activity
0.41	GO:0005347	ATP transmembrane transporter activity
0.41	GO:0015297	antiporter activity
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding

0.55	GO:0031966	mitochondrial membrane
0.55	GO:0019866	organelle inner membrane
0.34	GO:0031301	integral component of organelle membrane

tr|T1FNX5|T1FNX5_HELRO
Uncharacterized protein
Search

BCAS2

0.89	BCAS2, pre-mRNA processing factor

0.70	GO:0006397	mRNA processing
0.37	GO:0008380	RNA splicing
0.33	GO:0034314	Arp2/3 complex-mediated actin nucleation

0.33	GO:0005515	protein binding
0.33	GO:0008270	zinc ion binding
0.33	GO:0016874	ligase activity

0.52	GO:0071013	catalytic step 2 spliceosome
0.52	GO:0005662	DNA replication factor A complex
0.49	GO:0016607	nuclear speck
0.49	GO:0005684	U2-type spliceosomal complex
0.49	GO:0000974	Prp19 complex
0.48	GO:0005813	centrosome
0.48	GO:0071011	precatalytic spliceosome
0.37	GO:0005730	nucleolus
0.33	GO:0071203	WASH complex
0.33	GO:0005769	early endosome

0.33

GO:0016874

tr|T1FNX6|T1FNX6_HELRO
Uncharacterized protein
Search

FABP5

0.73	Fatty acid-binding protein, epidermal

0.39	GO:0006656	phosphatidylcholine biosynthetic process
0.38	GO:0015758	glucose transport
0.38	GO:0001947	heart looping
0.37	GO:0043009	chordate embryonic development
0.37	GO:0006006	glucose metabolic process
0.35	GO:0033552	response to vitamin B3
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0019433	triglyceride catabolic process
0.35	GO:0034694	response to prostaglandin
0.34	GO:0008544	epidermis development

0.72	GO:0008289	lipid binding
0.34	GO:0015349	thyroid hormone transmembrane transporter activity
0.34	GO:0033293	monocarboxylic acid binding
0.33	GO:0005515	protein binding

0.35	GO:0035578	azurophil granule lumen
0.35	GO:0030667	secretory granule membrane
0.34	GO:0070062	extracellular exosome
0.33	GO:0005654	nucleoplasm
0.33	GO:0005829	cytosol
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1FNX7|T1FNX7_HELRO
Uncharacterized protein
Search

0.52	Tubulin folding cofactor D

0.84	GO:0007021	tubulin complex assembly
0.84	GO:0007023	post-chaperonin tubulin folding pathway
0.76	GO:0043547	positive regulation of GTPase activity
0.53	GO:0031115	negative regulation of microtubule polymerization
0.51	GO:0048667	cell morphogenesis involved in neuron differentiation
0.49	GO:0000278	mitotic cell cycle
0.48	GO:0070830	bicellular tight junction assembly
0.48	GO:0034333	adherens junction assembly
0.48	GO:0000226	microtubule cytoskeleton organization
0.43	GO:0045196	establishment or maintenance of neuroblast polarity

0.84	GO:0048487	beta-tubulin binding
0.76	GO:0005096	GTPase activator activity
0.34	GO:0051087	chaperone binding
0.33	GO:0009036	Type II site-specific deoxyribonuclease activity
0.33	GO:0008137	NADH dehydrogenase (ubiquinone) activity

0.48	GO:0015630	microtubule cytoskeleton
0.48	GO:0016328	lateral plasma membrane
0.48	GO:0044430	cytoskeletal part
0.47	GO:0005923	bicellular tight junction
0.46	GO:0005912	adherens junction
0.44	GO:0099512	supramolecular fiber
0.34	GO:0005829	cytosol
0.34	GO:0055044	symplast
0.30	GO:0016021	integral component of membrane

0.33

EC:3.1.21.4

GO:0009036

tr|T1FNX8|T1FNX8_HELRO
Uncharacterized protein
Search

GGCT

0.43	Gamma-glutamyl cyclotransferase a

0.41	GO:0001836	release of cytochrome c from mitochondria
0.36	GO:0042381	hemolymph coagulation
0.36	GO:0006750	glutathione biosynthetic process
0.35	GO:0000387	spliceosomal snRNP assembly

0.81	GO:0003839	gamma-glutamylcyclotransferase activity
0.38	GO:0042803	protein homodimerization activity
0.36	GO:0016829	lyase activity

0.37	GO:0005829	cytosol
0.37	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.81

EC:2.3.2.4

GO:0003839

tr|T1FNX9|T1FNX9_HELRO
Uncharacterized protein
Search

PAICS

0.41	Phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase

0.71	GO:0006189	'de novo' IMP biosynthetic process
0.38	GO:0043473	pigmentation
0.38	GO:0060041	retina development in camera-type eye
0.37	GO:0043009	chordate embryonic development
0.34	GO:0000082	G1/S transition of mitotic cell cycle
0.34	GO:0009113	purine nucleobase biosynthetic process
0.32	GO:0016310	phosphorylation

0.79	GO:0004639	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
0.44	GO:0045296	cadherin binding
0.42	GO:0042802	identical protein binding
0.40	GO:0004638	phosphoribosylaminoimidazole carboxylase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0016301	kinase activity

0.36	GO:0070062	extracellular exosome
0.35	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.79	EC:6.3.2.6	GO:0004639
0.79	KEGG:R04591	GO:0004639

tr|T1FNY0|T1FNY0_HELRO
Uncharacterized protein
Search

NAGK

0.61	N-acetyl-D-glucosamine kinase

0.54	GO:0016310	phosphorylation
0.45	GO:0044262	cellular carbohydrate metabolic process
0.40	GO:0046348	amino sugar catabolic process
0.39	GO:0006054	N-acetylneuraminate metabolic process
0.38	GO:0006044	N-acetylglucosamine metabolic process
0.38	GO:0042737	drug catabolic process
0.37	GO:0046395	carboxylic acid catabolic process
0.35	GO:0006050	mannosamine metabolic process
0.35	GO:0006048	UDP-N-acetylglucosamine biosynthetic process
0.34	GO:0015991	ATP hydrolysis coupled proton transport

0.57	GO:0016301	kinase activity
0.35	GO:0097367	carbohydrate derivative binding
0.35	GO:0030554	adenyl nucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.34	GO:0016835	carbon-oxygen lyase activity
0.33	GO:0005515	protein binding
0.31	GO:0046872	metal ion binding

0.37	GO:0070062	extracellular exosome
0.35	GO:0033180	proton-transporting V-type ATPase, V1 domain
0.34	GO:0005829	cytosol

0.34

GO:0016773

tr|T1FNY1|T1FNY1_HELRO
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit
Search

DDOST

0.78	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

0.85	GO:0018279	protein N-linked glycosylation via asparagine
0.51	GO:0042110	T cell activation
0.49	GO:0034097	response to cytokine
0.38	GO:0034389	lipid particle organization
0.38	GO:0007030	Golgi organization
0.37	GO:0006334	nucleosome assembly
0.37	GO:0007018	microtubule-based movement
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0070828	heterochromatin organization
0.32	GO:0006355	regulation of transcription, DNA-templated

0.65	GO:0016757	transferase activity, transferring glycosyl groups
0.37	GO:0003777	microtubule motor activity
0.37	GO:0008017	microtubule binding
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0003677	DNA binding
0.34	GO:0003682	chromatin binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.72	GO:0005789	endoplasmic reticulum membrane
0.42	GO:0043234	protein complex
0.40	GO:1990234	transferase complex
0.37	GO:0000786	nucleosome
0.35	GO:0035577	azurophil granule membrane
0.35	GO:0005634	nucleus
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.65

GO:0016757

tr|T1FNY2|T1FNY2_HELRO
Peptidyl-prolyl cis-trans isomerase
Search

PPIC

0.47	Peptidyl-prolyl cis-trans isomerase C

0.72	GO:0000413	protein peptidyl-prolyl isomerization
0.66	GO:0006457	protein folding
0.33	GO:0042981	regulation of apoptotic process
0.33	GO:0016567	protein ubiquitination
0.32	GO:0046677	response to antibiotic
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression
0.32	GO:0009252	peptidoglycan biosynthetic process
0.32	GO:0008360	regulation of cell shape

0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.46	GO:0016018	cyclosporin A binding
0.33	GO:0005515	protein binding
0.33	GO:0043022	ribosome binding
0.33	GO:0004842	ubiquitin-protein transferase activity
0.32	GO:0050380	undecaprenyl-diphosphatase activity
0.32	GO:0003723	RNA binding
0.32	GO:0003677	DNA binding

0.34	GO:0070062	extracellular exosome
0.34	GO:0000178	exosome (RNase complex)
0.33	GO:0005829	cytosol
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.72	EC:5.2.1.8	GO:0003755
0.33	KEGG:R03876	GO:0004842

tr|T1FNY3|T1FNY3_HELRO
Uncharacterized protein
Search

tr|T1FNY4|T1FNY4_HELRO
Uncharacterized protein
Search

0.43	Serine proteinase

0.61	GO:0006508	proteolysis
0.46	GO:0002542	Factor XII activation
0.46	GO:0006898	receptor-mediated endocytosis
0.45	GO:0051919	positive regulation of fibrinolysis
0.45	GO:0010756	positive regulation of plasminogen activation
0.44	GO:0007596	blood coagulation
0.44	GO:0030194	positive regulation of blood coagulation
0.43	GO:0051788	response to misfolded protein
0.42	GO:0051604	protein maturation
0.38	GO:0042730	fibrinolysis

0.69	GO:0004252	serine-type endopeptidase activity
0.49	GO:0005044	scavenger receptor activity
0.45	GO:0005509	calcium ion binding
0.36	GO:0017080	sodium channel regulator activity
0.35	GO:0008061	chitin binding
0.33	GO:0051787	misfolded protein binding
0.33	GO:0070008	serine-type exopeptidase activity
0.33	GO:0005216	ion channel activity
0.32	GO:0016301	kinase activity
0.32	GO:0003779	actin binding

0.46	GO:0005576	extracellular region
0.35	GO:0031226	intrinsic component of plasma membrane
0.35	GO:0005737	cytoplasm
0.35	GO:0043025	neuronal cell body
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0031984	organelle subcompartment
0.33	GO:0031225	anchored component of membrane
0.33	GO:0019897	extrinsic component of plasma membrane
0.33	GO:0031982	vesicle
0.32	GO:0043231	intracellular membrane-bounded organelle

0.69

GO:0004252

tr|T1FNY5|T1FNY5_HELRO
Uncharacterized protein
Search

SLC17A5

0.61	Vesicular glutamate transporter

0.55	GO:0055085	transmembrane transport
0.43	GO:0015739	sialic acid transport
0.35	GO:0042137	sequestering of neurotransmitter
0.34	GO:0051938	L-glutamate import
0.34	GO:0016188	synaptic vesicle maturation
0.34	GO:0070050	neuron cellular homeostasis
0.34	GO:0035249	synaptic transmission, glutamatergic
0.34	GO:0007616	long-term memory
0.34	GO:0099504	synaptic vesicle cycle
0.34	GO:0060079	excitatory postsynaptic potential

0.43	GO:0015136	sialic acid transmembrane transporter activity
0.35	GO:0015293	symporter activity
0.35	GO:0008068	extracellularly glutamate-gated chloride channel activity
0.34	GO:0015114	phosphate ion transmembrane transporter activity
0.33	GO:0015081	sodium ion transmembrane transporter activity
0.33	GO:0022853	active ion transmembrane transporter activity
0.33	GO:0016758	transferase activity, transferring hexosyl groups
0.32	GO:0003677	DNA binding

0.42	GO:0005765	lysosomal membrane
0.39	GO:0031410	cytoplasmic vesicle
0.38	GO:0005829	cytosol
0.36	GO:0098793	presynapse
0.36	GO:0005886	plasma membrane
0.36	GO:0012506	vesicle membrane
0.35	GO:0012505	endomembrane system
0.35	GO:0044300	cerebellar mossy fiber
0.34	GO:0060076	excitatory synapse
0.34	GO:0098794	postsynapse

0.33

GO:0016758

tr|T1FNY6|T1FNY6_HELRO
Uncharacterized protein
Search

0.45	U2 snRNP auxiliary factor large subunit

0.70	GO:0008380	RNA splicing
0.68	GO:0006397	mRNA processing
0.38	GO:0046660	female sex differentiation
0.35	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.35	GO:0046833	positive regulation of RNA export from nucleus
0.34	GO:0032958	inositol phosphate biosynthetic process
0.34	GO:0051168	nuclear export
0.33	GO:0006508	proteolysis
0.32	GO:0016310	phosphorylation

0.59	GO:0003723	RNA binding
0.33	GO:0008234	cysteine-type peptidase activity
0.33	GO:0005515	protein binding
0.33	GO:0016301	kinase activity
0.32	GO:0004386	helicase activity
0.32	GO:0030554	adenyl nucleotide binding
0.31	GO:0032555	purine ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.60	GO:0005634	nucleus
0.38	GO:0030529	intracellular ribonucleoprotein complex
0.38	GO:0019013	viral nucleocapsid
0.37	GO:0031974	membrane-enclosed lumen
0.36	GO:0043234	protein complex
0.35	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.33

GO:0008234

tr|T1FNY7|T1FNY7_HELRO
Uncharacterized protein
Search

ACAA2

0.45	Acetyl-Coenzyme A acyltransferase

0.42	GO:1902109	negative regulation of mitochondrial membrane permeability involved in apoptotic process
0.41	GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
0.40	GO:0071456	cellular response to hypoxia
0.40	GO:0006635	fatty acid beta-oxidation
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.64	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
0.34	GO:0003779	actin binding
0.34	GO:0003774	motor activity
0.33	GO:0003700	DNA binding transcription factor activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.38	GO:0005739	mitochondrion
0.36	GO:0019866	organelle inner membrane
0.34	GO:0016459	myosin complex
0.30	GO:0031224	intrinsic component of membrane

0.64

GO:0016747

tr|T1FNY8|T1FNY8_HELRO
Uncharacterized protein
Search

PP2B-14D

0.38	Serine/threonine-protein phosphatase

0.57	GO:0006470	protein dephosphorylation
0.44	GO:1900739	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
0.44	GO:1901030	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
0.43	GO:1903749	positive regulation of establishment of protein localization to mitochondrion
0.41	GO:0007420	brain development
0.41	GO:1905477	positive regulation of protein localization to membrane

0.57	GO:0004721	phosphoprotein phosphatase activity
0.41	GO:0005516	calmodulin binding
0.36	GO:0046872	metal ion binding

0.42	GO:0070062	extracellular exosome
0.39	GO:0005829	cytosol
0.37	GO:0005739	mitochondrion

0.57

GO:0004721

tr|T1FNY9|T1FNY9_HELRO
Uncharacterized protein
Search

UBASH3B

0.73	Ubiquitin-associated and SH3 domain-containing protein B

0.84	GO:0045779	negative regulation of bone resorption
0.84	GO:0090331	negative regulation of platelet aggregation
0.83	GO:0045671	negative regulation of osteoclast differentiation
0.82	GO:0070527	platelet aggregation
0.81	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.80	GO:0051279	regulation of release of sequestered calcium ion into cytosol
0.77	GO:0043393	regulation of protein binding
0.75	GO:0006469	negative regulation of protein kinase activity
0.70	GO:0009968	negative regulation of signal transduction
0.69	GO:0035335	peptidyl-tyrosine dephosphorylation

0.78	GO:0051219	phosphoprotein binding
0.70	GO:0004725	protein tyrosine phosphatase activity
0.69	GO:0042802	identical protein binding
0.46	GO:0031625	ubiquitin protein ligase binding
0.40	GO:0004619	phosphoglycerate mutase activity
0.39	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.39	GO:0000987	proximal promoter sequence-specific DNA binding
0.37	GO:0046983	protein dimerization activity

0.44	GO:0005634	nucleus
0.43	GO:0005794	Golgi apparatus
0.42	GO:0043233	organelle lumen
0.39	GO:0044446	intracellular organelle part

0.70

GO:0004725

tr|T1FNZ0|T1FNZ0_HELRO
Uncharacterized protein
Search

0.11	Kelch-like protein 9

0.79	GO:0014029	neural crest formation
0.76	GO:0014032	neural crest cell development
0.74	GO:0006513	protein monoubiquitination
0.58	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.53	GO:0008584	male gonad development
0.52	GO:0007286	spermatid development
0.52	GO:0009566	fertilization
0.43	GO:0006417	regulation of translation
0.38	GO:0043687	post-translational protein modification

0.62	GO:0004842	ubiquitin-protein transferase activity
0.43	GO:0050290	sphingomyelin phosphodiesterase D activity
0.35	GO:0005515	protein binding

0.82	GO:0031463	Cul3-RING ubiquitin ligase complex
0.45	GO:0005819	spindle
0.43	GO:0005794	Golgi apparatus
0.36	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.43	EC:3.1.4.41	GO:0050290
0.62	KEGG:R03876	GO:0004842

tr|T1FNZ1|T1FNZ1_HELRO
Uncharacterized protein
Search

RHBG

0.80	Ammonium transporter Rh type B-B

0.77	GO:0072488	ammonium transmembrane transport
0.45	GO:0070634	transepithelial ammonium transport
0.43	GO:0015695	organic cation transport
0.41	GO:0015840	urea transport
0.37	GO:0097272	ammonia homeostasis

0.77	GO:0008519	ammonium transmembrane transporter activity
0.44	GO:0030506	ankyrin binding
0.35	GO:0051087	chaperone binding

0.46	GO:0014731	spectrin-associated cytoskeleton
0.45	GO:0016323	basolateral plasma membrane
0.43	GO:0046658	anchored component of plasma membrane
0.42	GO:0005887	integral component of plasma membrane
0.39	GO:0030659	cytoplasmic vesicle membrane

tr|T1FNZ2|T1FNZ2_HELRO
Uncharacterized protein
Search

TMEM87B

0.79	Putative lung seven transmembrane receptor

0.48

GO:0042147

retrograde transport, endosome to Golgi

0.33

GO:0005509

calcium ion binding

0.44	GO:0005829	cytosol
0.36	GO:0000139	Golgi membrane
0.34	GO:0031985	Golgi cisterna
0.30	GO:0044425	membrane part

tr|T1FNZ3|T1FNZ3_HELRO
Mitogen-activated protein kinase
Search

MAPK14

0.58	Mitogen-activated protein kinase

0.79	GO:0000165	MAPK cascade
0.49	GO:0014835	myoblast differentiation involved in skeletal muscle regeneration
0.49	GO:2001184	positive regulation of interleukin-12 secretion
0.49	GO:0090336	positive regulation of brown fat cell differentiation
0.49	GO:1905050	positive regulation of metallopeptidase activity
0.49	GO:0002741	positive regulation of cytokine secretion involved in immune response
0.49	GO:1901741	positive regulation of myoblast fusion
0.49	GO:0090400	stress-induced premature senescence
0.48	GO:0071223	cellular response to lipoteichoic acid
0.48	GO:0010759	positive regulation of macrophage chemotaxis

0.81	GO:0004707	MAP kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0048273	mitogen-activated protein kinase p38 binding
0.49	GO:0051525	NFAT protein binding
0.46	GO:0019903	protein phosphatase binding

0.46	GO:0016607	nuclear speck
0.45	GO:0000922	spindle pole
0.42	GO:0005829	cytosol
0.39	GO:0005739	mitochondrion

0.81	EC:2.7.11.24	GO:0004707
0.81	KEGG:R00162	GO:0004707

tr|T1FNZ4|T1FNZ4_HELRO
Uncharacterized protein
Search

FNBP1

0.88	Formin-binding protein 1

0.71	GO:0006897	endocytosis
0.40	GO:0007399	nervous system development
0.39	GO:0030154	cell differentiation
0.38	GO:0061024	membrane organization

0.49	GO:0042802	identical protein binding
0.48	GO:0008289	lipid binding

0.52	GO:0005905	clathrin-coated pit
0.51	GO:0005764	lysosome
0.50	GO:0005938	cell cortex
0.48	GO:0031410	cytoplasmic vesicle
0.47	GO:0005856	cytoskeleton
0.41	GO:0005886	plasma membrane
0.39	GO:0005829	cytosol

tr|T1FNZ5|T1FNZ5_HELRO
Uncharacterized protein
Search

0.71	LIM domain-containing protein jub

0.46	GO:0035331	negative regulation of hippo signaling
0.46	GO:0035329	hippo signaling
0.46	GO:2000637	positive regulation of gene silencing by miRNA
0.44	GO:0060429	epithelium development
0.44	GO:0001666	response to hypoxia
0.43	GO:1903507	negative regulation of nucleic acid-templated transcription
0.42	GO:0045572	positive regulation of imaginal disc growth
0.42	GO:0000278	mitotic cell cycle
0.42	GO:0007010	cytoskeleton organization
0.42	GO:0120031	plasma membrane bounded cell projection assembly

0.54	GO:0046872	metal ion binding
0.44	GO:0003714	transcription corepressor activity
0.39	GO:0045294	alpha-catenin binding
0.38	GO:0003779	actin binding
0.37	GO:0003682	chromatin binding
0.37	GO:0032403	protein complex binding
0.34	GO:0005096	GTPase activator activity
0.32	GO:0016740	transferase activity

0.46	GO:0005912	adherens junction
0.45	GO:0005911	cell-cell junction
0.44	GO:0000932	P-body
0.43	GO:0005815	microtubule organizing center
0.42	GO:0005667	transcription factor complex
0.41	GO:0045179	apical cortex
0.41	GO:0120025	plasma membrane bounded cell projection
0.38	GO:0005634	nucleus
0.38	GO:0030055	cell-substrate junction
0.38	GO:0031252	cell leading edge

0.32

GO:0016740

tr|T1FNZ6|T1FNZ6_HELRO
Uncharacterized protein
Search

0.83	Copine III

0.64	GO:0038128	ERBB2 signaling pathway
0.64	GO:0071277	cellular response to calcium ion
0.57	GO:0030335	positive regulation of cell migration
0.57	GO:0071363	cellular response to growth factor stimulus
0.47	GO:0006468	protein phosphorylation
0.46	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway
0.46	GO:1901223	negative regulation of NIK/NF-kappaB signaling
0.44	GO:0043392	negative regulation of DNA binding
0.44	GO:0051897	positive regulation of protein kinase B signaling
0.44	GO:1990138	neuron projection extension

0.61	GO:0048306	calcium-dependent protein binding
0.59	GO:0030971	receptor tyrosine kinase binding
0.59	GO:0005544	calcium-dependent phospholipid binding
0.51	GO:0004674	protein serine/threonine kinase activity
0.45	GO:0051059	NF-kappaB binding
0.45	GO:0001786	phosphatidylserine binding
0.43	GO:0003723	RNA binding
0.42	GO:0042803	protein homodimerization activity
0.40	GO:0005509	calcium ion binding
0.39	GO:0004175	endopeptidase activity

0.64	GO:0031965	nuclear membrane
0.64	GO:0031981	nuclear lumen
0.58	GO:0005925	focal adhesion
0.53	GO:0005829	cytosol
0.47	GO:0005739	mitochondrion
0.46	GO:0043232	intracellular non-membrane-bounded organelle
0.46	GO:0005886	plasma membrane
0.43	GO:0035577	azurophil granule membrane
0.43	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.51

GO:0004674

tr|T1FNZ7|T1FNZ7_HELRO
Uncharacterized protein
Search

PCGF3

0.93	Polycomb group RING finger protein 3

0.84	GO:0036353	histone H2A-K119 monoubiquitination
0.74	GO:0060819	inactivation of X chromosome by genetic imprinting
0.48	GO:0045892	negative regulation of transcription, DNA-templated
0.40	GO:0006351	transcription, DNA-templated
0.35	GO:0007568	aging

0.57	GO:0008022	protein C-terminus binding
0.38	GO:0046872	metal ion binding
0.34	GO:0003677	DNA binding

0.82	GO:0031519	PcG protein complex
0.70	GO:0000805	X chromosome
0.64	GO:0005654	nucleoplasm
0.52	GO:0000152	nuclear ubiquitin ligase complex
0.30	GO:0031224	intrinsic component of membrane

tr|T1FNZ8|T1FNZ8_HELRO
Glutamate dehydrogenase
Search

0.46	Mitochondrial glutamate dehydrogenase 1

0.59	GO:0006520	cellular amino acid metabolic process
0.52	GO:0055114	oxidation-reduction process
0.37	GO:0032094	response to food
0.35	GO:0032024	positive regulation of insulin secretion
0.34	GO:0072350	tricarboxylic acid metabolic process

0.75	GO:0016639	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
0.34	GO:0016758	transferase activity, transferring hexosyl groups

0.34	GO:0005759	mitochondrial matrix
0.33	GO:0031966	mitochondrial membrane
0.33	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.75

EC:1.4.1

GO:0016639

tr|T1FNZ9|T1FNZ9_HELRO
Uncharacterized protein
Search

0.71	Multifunctional chaperone

0.44	GO:0040024	dauer larval development
0.44	GO:0051220	cytoplasmic sequestering of protein
0.43	GO:0042308	negative regulation of protein import into nucleus
0.37	GO:0030590	first cell cycle pseudocleavage
0.37	GO:0010070	zygote asymmetric cell division
0.37	GO:0035046	pronuclear migration
0.37	GO:0009949	polarity specification of anterior/posterior axis
0.37	GO:0045167	asymmetric protein localization involved in cell fate determination
0.36	GO:0055114	oxidation-reduction process
0.36	GO:0010286	heat acclimation

0.77	GO:0019904	protein domain specific binding
0.40	GO:0004497	monooxygenase activity
0.40	GO:0008134	transcription factor binding
0.32	GO:0016301	kinase activity

0.38	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm
0.33	GO:0071944	cell periphery

tr|T1FP00|T1FP00_HELRO
Transmembrane 9 superfamily member
Search

0.54	Transmembrane 9 superfamily member

0.30

GO:0044425

membrane part

tr|T1FP01|T1FP01_HELRO
Protein Wnt
Search

0.77	GO:0016055	Wnt signaling pathway
0.70	GO:0007275	multicellular organism development
0.46	GO:0030154	cell differentiation
0.44	GO:0060560	developmental growth involved in morphogenesis
0.43	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.42	GO:0120036	plasma membrane bounded cell projection organization
0.42	GO:0061061	muscle structure development
0.42	GO:0016049	cell growth
0.41	GO:0051270	regulation of cellular component movement
0.41	GO:0040017	positive regulation of locomotion

0.73	GO:0005102	receptor binding
0.37	GO:0044212	transcription regulatory region DNA binding
0.36	GO:0030295	protein kinase activator activity
0.36	GO:0005096	GTPase activator activity
0.35	GO:0030545	receptor regulator activity
0.34	GO:0019904	protein domain specific binding
0.33	GO:0003700	DNA binding transcription factor activity
0.32	GO:0005328	neurotransmitter:sodium symporter activity

0.76	GO:0005578	proteinaceous extracellular matrix
0.42	GO:0005615	extracellular space
0.34	GO:0009986	cell surface
0.33	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1FP02|T1FP02_HELRO
Uncharacterized protein
Search

0.89	HUS1 checkpoint clamp component

0.81	GO:0000077	DNA damage checkpoint
0.49	GO:0044778	meiotic DNA integrity checkpoint
0.47	GO:0033314	mitotic DNA replication checkpoint
0.44	GO:0000724	double-strand break repair via homologous recombination
0.43	GO:0006289	nucleotide-excision repair
0.34	GO:0071479	cellular response to ionizing radiation

0.84	GO:0030896	checkpoint clamp complex
0.73	GO:0005730	nucleolus
0.46	GO:0035861	site of double-strand break
0.30	GO:0016020	membrane

tr|T1FP03|T1FP03_HELRO
Uncharacterized protein
Search

RPL27A

0.47	60S ribosomal protein L27a (inferred by orthology to a human protein)

0.60	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.32	GO:1901135	carbohydrate derivative metabolic process

0.63	GO:0003735	structural constituent of ribosome
0.39	GO:0003723	RNA binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0016787	hydrolase activity

0.68	GO:0015934	large ribosomal subunit
0.44	GO:0022626	cytosolic ribosome
0.37	GO:0005783	endoplasmic reticulum
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016787

tr|T1FP04|T1FP04_HELRO
Uncharacterized protein
Search

0.82	SecY translocase

0.65	GO:0015031	protein transport
0.46	GO:0034761	positive regulation of iron ion transmembrane transport
0.45	GO:0046598	positive regulation of viral entry into host cell
0.45	GO:0008258	head involution
0.44	GO:0007391	dorsal closure
0.44	GO:0042335	cuticle development
0.43	GO:0098586	cellular response to virus
0.42	GO:0010942	positive regulation of cell death
0.41	GO:0010507	negative regulation of autophagy
0.34	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER

0.36

GO:0070569

uridylyltransferase activity

0.45	GO:0045169	fusome
0.43	GO:0005791	rough endoplasmic reticulum
0.33	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

tr|T1FP05|T1FP05_HELRO
Uncharacterized protein
Search

0.33	GO:0008302	female germline ring canal formation, actin assembly
0.33	GO:0045614	negative regulation of plasmatocyte differentiation
0.33	GO:0035203	regulation of lamellocyte differentiation
0.33	GO:0030708	germarium-derived female germ-line cyst encapsulation
0.33	GO:0007303	cytoplasmic transport, nurse cell to oocyte
0.33	GO:0048149	behavioral response to ethanol
0.33	GO:0007616	long-term memory
0.33	GO:0048581	negative regulation of post-embryonic development
0.33	GO:0008045	motor neuron axon guidance
0.33	GO:0045214	sarcomere organization

0.74	GO:0003779	actin binding
0.32	GO:0030246	carbohydrate binding

0.33	GO:0035182	female germline ring canal outer rim
0.33	GO:0035183	female germline ring canal inner rim
0.33	GO:0045179	apical cortex
0.33	GO:0070938	contractile ring
0.33	GO:0030018	Z disc
0.33	GO:0005884	actin filament
0.32	GO:0048471	perinuclear region of cytoplasm
0.32	GO:0005829	cytosol
0.32	GO:0005634	nucleus
0.32	GO:0005886	plasma membrane

tr|T1FP06|T1FP06_HELRO
Uncharacterized protein
Search

MYO1D

0.78	Unconventional myosin-Id

0.74	GO:0007018	microtubule-based movement
0.49	GO:0010923	negative regulation of phosphatase activity
0.43	GO:0051641	cellular localization
0.39	GO:0098927	vesicle-mediated transport between endosomal compartments
0.37	GO:0030900	forebrain development
0.37	GO:0071976	cell gliding
0.36	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.36	GO:0072678	T cell migration
0.36	GO:0002456	T cell mediated immunity
0.35	GO:0031589	cell-substrate adhesion

0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.74	GO:0003779	actin binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0019904	protein domain specific binding
0.39	GO:0030898	actin-dependent ATPase activity
0.38	GO:0000146	microfilament motor activity
0.38	GO:0005516	calmodulin binding

0.77	GO:0016459	myosin complex
0.48	GO:0005903	brush border
0.48	GO:0043209	myelin sheath
0.47	GO:0043025	neuronal cell body
0.47	GO:0030424	axon
0.39	GO:0097440	apical dendrite
0.39	GO:0031256	leading edge membrane
0.38	GO:0016323	basolateral plasma membrane
0.38	GO:0005790	smooth endoplasmic reticulum
0.38	GO:0031982	vesicle

tr|T1FP07|T1FP07_HELRO
ATP-dependent 6-phosphofructokinase
Search

0.44	ATP-dependent 6-phosphofructokinase

0.79	GO:0006002	fructose 6-phosphate metabolic process
0.78	GO:0061615	glycolytic process through fructose-6-phosphate

0.79	GO:0003872	6-phosphofructokinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0046872	metal ion binding

0.49	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.79

EC:2.7.1.11

GO:0003872

tr|T1FP08|T1FP08_HELRO
Uncharacterized protein
Search

tr|T1FP09|T1FP09_HELRO
Glucosamine-6-phosphate isomerase
Search

GNPDA1

0.72	Glucosamine-6-phosphate isomerase

0.78	GO:0006044	N-acetylglucosamine metabolic process
0.60	GO:0005975	carbohydrate metabolic process
0.57	GO:0006043	glucosamine catabolic process
0.42	GO:0006091	generation of precursor metabolites and energy
0.36	GO:0019953	sexual reproduction
0.35	GO:0045950	negative regulation of mitotic recombination
0.35	GO:1903775	regulation of DNA double-strand break processing
0.34	GO:0006002	fructose 6-phosphate metabolic process
0.34	GO:0045132	meiotic chromosome segregation
0.34	GO:0051304	chromosome separation

0.81	GO:0004342	glucosamine-6-phosphate deaminase activity
0.34	GO:0003682	chromatin binding
0.33	GO:0005515	protein binding
0.32	GO:0003676	nucleic acid binding

0.48	GO:0005737	cytoplasm
0.37	GO:0070062	extracellular exosome
0.34	GO:0000775	chromosome, centromeric region
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.81	EC:3.5.99.6	GO:0004342
0.81	KEGG:R00765	GO:0004342

tr|T1FP10|T1FP10_HELRO
Probable cytosolic iron-sulfur protein assembly protein CIAO1 homolog
Search

CIAO1

0.73	Probable cytosolic iron-sulfur protein assembly protein 1

0.72	GO:0031163	metallo-sulfur cluster assembly
0.64	GO:0006790	sulfur compound metabolic process
0.61	GO:0051188	cofactor biosynthetic process
0.43	GO:0002098	tRNA wobble uridine modification
0.34	GO:0006298	mismatch repair
0.33	GO:0009116	nucleoside metabolic process
0.33	GO:0055085	transmembrane transport
0.32	GO:0055114	oxidation-reduction process

0.34	GO:0051539	4 iron, 4 sulfur cluster binding
0.34	GO:0005515	protein binding
0.34	GO:0030983	mismatched DNA binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0016746	transferase activity, transferring acyl groups
0.33	GO:0046872	metal ion binding
0.32	GO:0016887	ATPase activity
0.32	GO:0016491	oxidoreductase activity

0.84	GO:0097361	CIA complex
0.40	GO:0005634	nucleus
0.35	GO:0019013	viral nucleocapsid
0.34	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016020	membrane

0.33

EC:2.3

GO:0016746

tr|T1FP11|T1FP11_HELRO
Glutamine synthetase
Search

0.46	Glutamine synthetase

0.76	GO:0006542	glutamine biosynthetic process
0.38	GO:0032094	response to food
0.34	GO:0009749	response to glucose
0.34	GO:0008283	cell proliferation
0.34	GO:0009267	cellular response to starvation

0.76	GO:0004356	glutamate-ammonia ligase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0004351	glutamate decarboxylase activity
0.33	GO:0042802	identical protein binding

0.35	GO:0097386	glial cell projection
0.34	GO:0043209	myelin sheath
0.34	GO:0044297	cell body
0.33	GO:0005739	mitochondrion
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.76	EC:6.3.1.2	GO:0004356
0.76	KEGG:R00253	GO:0004356

tr|T1FP12|T1FP12_HELRO
Uncharacterized protein
Search

AVL9

0.60	Late secretory pathway protein AVL9

0.69

GO:0016477

cell migration

0.73	GO:0055037	recycling endosome
0.30	GO:0044425	membrane part

tr|T1FP13|T1FP13_HELRO
Uncharacterized protein
Search

UGP2

0.53	UTP--glucose-1-phosphate uridylyltransferase

0.77	GO:0006011	UDP-glucose metabolic process
0.43	GO:0005977	glycogen metabolic process
0.40	GO:0019255	glucose 1-phosphate metabolic process
0.35	GO:0006065	UDP-glucuronate biosynthetic process
0.34	GO:0009250	glucan biosynthetic process

0.79	GO:0003983	UTP:glucose-1-phosphate uridylyltransferase activity
0.47	GO:0042802	identical protein binding
0.40	GO:0032557	pyrimidine ribonucleotide binding
0.38	GO:0005536	glucose binding
0.34	GO:0046872	metal ion binding
0.32	GO:0003677	DNA binding

0.37	GO:0070062	extracellular exosome
0.36	GO:0005737	cytoplasm
0.35	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.79	EC:2.7.7.9	GO:0003983
0.79	KEGG:R00289	GO:0003983

tr|T1FP14|T1FP14_HELRO
Serine/threonine-protein phosphatase
Search

PPP1CC

0.49	Serine/threonine-protein phosphatase

0.72	GO:0006470	protein dephosphorylation
0.56	GO:0043153	entrainment of circadian clock by photoperiod
0.54	GO:0032922	circadian regulation of gene expression
0.48	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
0.46	GO:0048754	branching morphogenesis of an epithelial tube
0.46	GO:0030324	lung development
0.46	GO:0046822	regulation of nucleocytoplasmic transport
0.45	GO:0098609	cell-cell adhesion
0.41	GO:0005977	glycogen metabolic process
0.39	GO:0051301	cell division

0.77	GO:0004722	protein serine/threonine phosphatase activity
0.53	GO:0046872	metal ion binding
0.48	GO:0098641	cadherin binding involved in cell-cell adhesion
0.47	GO:0047485	protein N-terminus binding
0.45	GO:0019901	protein kinase binding
0.41	GO:0008157	protein phosphatase 1 binding
0.39	GO:0005521	lamin binding
0.39	GO:0032403	protein complex binding
0.38	GO:0008022	protein C-terminus binding
0.37	GO:0019904	protein domain specific binding

0.84	GO:0000164	protein phosphatase type 1 complex
0.71	GO:0072357	PTW/PP1 phosphatase complex
0.52	GO:0000784	nuclear chromosome, telomeric region
0.47	GO:0005913	cell-cell adherens junction
0.45	GO:0005654	nucleoplasm
0.45	GO:0005730	nucleolus
0.45	GO:0005741	mitochondrial outer membrane
0.43	GO:0005829	cytosol
0.41	GO:0032154	cleavage furrow
0.41	GO:0043197	dendritic spine

tr|T1FP15|T1FP15_HELRO
Uncharacterized protein
Search

PTPRFA

0.29	Tyrosine-protein phosphatase Lar

0.75	GO:0035335	peptidyl-tyrosine dephosphorylation
0.43	GO:1900121	negative regulation of receptor binding
0.43	GO:0031175	neuron projection development
0.43	GO:0048679	regulation of axon regeneration
0.42	GO:0031099	regeneration
0.41	GO:0006928	movement of cell or subcellular component
0.40	GO:0040011	locomotion
0.39	GO:0051674	localization of cell
0.38	GO:0048667	cell morphogenesis involved in neuron differentiation
0.38	GO:0120039	plasma membrane bounded cell projection morphogenesis

0.75	GO:0004725	protein tyrosine phosphatase activity
0.44	GO:0035373	chondroitin sulfate proteoglycan binding
0.40	GO:0032403	protein complex binding
0.36	GO:0008201	heparin binding
0.35	GO:0019198	transmembrane receptor protein phosphatase activity

0.41	GO:0043025	neuronal cell body
0.40	GO:0043005	neuron projection
0.34	GO:0070062	extracellular exosome
0.33	GO:0005887	integral component of plasma membrane

0.75

GO:0004725

tr|T1FP16|T1FP16_HELRO
Uncharacterized protein
Search

HCRTR2

0.81	Hypocretin (Orexin) receptor 2 (Fragment)

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.57	GO:0007631	feeding behavior
0.48	GO:0022410	circadian sleep/wake cycle process
0.45	GO:1901652	response to peptide
0.44	GO:0030186	melatonin metabolic process
0.43	GO:0032870	cellular response to hormone stimulus
0.43	GO:0045187	regulation of circadian sleep/wake cycle, sleep
0.39	GO:0043006	activation of phospholipase A2 activity by calcium-mediated signaling
0.38	GO:0007417	central nervous system development
0.37	GO:0048016	inositol phosphate-mediated signaling

0.76	GO:0008528	G-protein coupled peptide receptor activity
0.45	GO:0042277	peptide binding
0.38	GO:0061778	intracellular chloride channel activity
0.36	GO:0022839	ion gated channel activity
0.36	GO:0008381	mechanosensitive ion channel activity
0.35	GO:0005525	GTP binding
0.34	GO:0004896	cytokine receptor activity
0.34	GO:0035717	chemokine (C-C motif) ligand 7 binding
0.34	GO:0071791	chemokine (C-C motif) ligand 5 binding
0.33	GO:0004435	phosphatidylinositol phospholipase C activity

0.41	GO:0005887	integral component of plasma membrane
0.37	GO:0097730	non-motile cilium
0.33	GO:0009897	external side of plasma membrane
0.32	GO:0005622	intracellular

0.33	EC:3.1.4.11	GO:0004435
0.33	KEGG:R03435	GO:0004435

tr|T1FP17|T1FP17_HELRO
Uncharacterized protein
Search

UBE2A

0.53	Ubiquitin-conjugating enzyme

0.50	GO:0016574	histone ubiquitination
0.49	GO:0000209	protein polyubiquitination
0.48	GO:0051865	protein autoubiquitination
0.47	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.47	GO:0009411	response to UV
0.46	GO:0060135	maternal process involved in female pregnancy
0.46	GO:0008284	positive regulation of cell proliferation
0.45	GO:0006281	DNA repair
0.45	GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
0.45	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0031625	ubiquitin protein ligase binding
0.49	GO:0061631	ubiquitin conjugating enzyme activity
0.44	GO:0061630	ubiquitin protein ligase activity
0.44	GO:0002039	p53 binding
0.42	GO:0019904	protein domain specific binding
0.37	GO:0016874	ligase activity
0.34	GO:0043130	ubiquitin binding

0.53	GO:0033503	HULC complex
0.48	GO:0001741	XY body
0.46	GO:0000790	nuclear chromatin
0.37	GO:0005737	cytoplasm
0.33	GO:0005654	nucleoplasm

0.37

GO:0016874

tr|T1FP18|T1FP18_HELRO
Uncharacterized protein
Search

ATP6V1B2

0.71	Vacuolar ATP synthase subunit B

0.75	GO:0015991	ATP hydrolysis coupled proton transport
0.61	GO:0046034	ATP metabolic process
0.40	GO:0051453	regulation of intracellular pH
0.37	GO:0060142	regulation of syncytium formation by plasma membrane fusion
0.37	GO:0045851	pH reduction
0.37	GO:0001666	response to hypoxia
0.36	GO:0043068	positive regulation of programmed cell death
0.36	GO:0008219	cell death
0.36	GO:0098609	cell-cell adhesion
0.35	GO:0033572	transferrin transport

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0046961	proton-transporting ATPase activity, rotational mechanism
0.33	GO:0005515	protein binding

0.80	GO:0033180	proton-transporting V-type ATPase, V1 domain
0.50	GO:0005902	microvillus
0.49	GO:0001726	ruffle
0.49	GO:0043209	myelin sheath
0.44	GO:0005829	cytosol
0.41	GO:0043227	membrane-bounded organelle
0.40	GO:0005886	plasma membrane
0.39	GO:0043229	intracellular organelle
0.36	GO:0012505	endomembrane system
0.36	GO:0043230	extracellular organelle

tr|T1FP19|T1FP19_HELRO
Uncharacterized protein
Search

0.61	LOW QUALITY PROTEIN: tubulin epsilon chain

0.72	GO:0007017	microtubule-based process
0.36	GO:0009408	response to heat
0.36	GO:0009190	cyclic nucleotide biosynthetic process
0.35	GO:0006457	protein folding
0.34	GO:0035556	intracellular signal transduction
0.33	GO:0006030	chitin metabolic process
0.33	GO:0007010	cytoskeleton organization
0.33	GO:0022402	cell cycle process

0.68	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0031072	heat shock protein binding
0.36	GO:0016849	phosphorus-oxygen lyase activity
0.35	GO:0051082	unfolded protein binding
0.35	GO:0030554	adenyl nucleotide binding
0.35	GO:0008144	drug binding

0.73	GO:0005874	microtubule
0.34	GO:0005815	microtubule organizing center
0.33	GO:0005737	cytoplasm
0.32	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.36

EC:4.6

GO:0016849

tr|T1FP20|T1FP20_HELRO
Uncharacterized protein
Search

MYO7A

0.72	Unconventional myosin-VIIa

0.73	GO:0007018	microtubule-based movement
0.52	GO:0035315	hair cell differentiation
0.51	GO:0060122	inner ear receptor cell stereocilium organization
0.50	GO:0050954	sensory perception of mechanical stimulus
0.49	GO:0001845	phagolysosome assembly
0.49	GO:0051904	pigment granule transport
0.48	GO:0048563	post-embryonic animal organ morphogenesis
0.48	GO:0060563	neuroepithelial cell differentiation
0.48	GO:0030048	actin filament-based movement
0.48	GO:0050957	equilibrioception

0.76	GO:0051015	actin filament binding
0.74	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0000146	microfilament motor activity
0.46	GO:0030507	spectrin binding
0.45	GO:0019904	protein domain specific binding
0.44	GO:0005516	calmodulin binding

0.76	GO:0016459	myosin complex
0.48	GO:0032391	photoreceptor connecting cilium
0.48	GO:0032420	stereocilium
0.48	GO:0042470	melanosome
0.47	GO:0045177	apical part of cell
0.47	GO:0001917	photoreceptor inner segment
0.46	GO:0001750	photoreceptor outer segment
0.45	GO:0005765	lysosomal membrane
0.45	GO:0098590	plasma membrane region
0.44	GO:0045202	synapse

tr|T1FP21|T1FP21_HELRO
Uncharacterized protein
Search

0.40	Tetracycline resistance

0.55	GO:0055085	transmembrane transport
0.50	GO:0043252	sodium-independent organic anion transport
0.47	GO:0015904	tetracycline transport
0.39	GO:0016578	histone deubiquitination
0.38	GO:0048477	oogenesis
0.37	GO:0045893	positive regulation of transcription, DNA-templated
0.35	GO:0006351	transcription, DNA-templated
0.35	GO:0006915	apoptotic process
0.34	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway

0.51	GO:0005215	transporter activity
0.38	GO:0003713	transcription coactivator activity
0.36	GO:0008270	zinc ion binding
0.35	GO:0016746	transferase activity, transferring acyl groups
0.33	GO:0043531	ADP binding
0.33	GO:0004871	signal transducer activity
0.33	GO:0003700	DNA binding transcription factor activity
0.32	GO:0003677	DNA binding

0.51	GO:0031526	brush border membrane
0.46	GO:0030659	cytoplasmic vesicle membrane
0.39	GO:0071819	DUBm complex
0.38	GO:0000124	SAGA complex
0.36	GO:0032040	small-subunit processome
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:2.3

GO:0016746

tr|T1FP22|T1FP22_HELRO
Uncharacterized protein
Search

0.80	Nicotinic acetylcholine receptor subunit type A

0.77	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.46	GO:0017085	response to insecticide
0.46	GO:0007271	synaptic transmission, cholinergic
0.45	GO:0046716	muscle cell cellular homeostasis
0.38	GO:0006812	cation transport

0.80	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0099600	transmembrane receptor activity
0.42	GO:0005509	calcium ion binding

0.76	GO:0045211	postsynaptic membrane
0.72	GO:0030054	cell junction
0.45	GO:0005892	acetylcholine-gated channel complex
0.35	GO:0042995	cell projection

tr|T1FP23|T1FP23_HELRO
Uncharacterized protein
Search

tr|T1FP24|T1FP24_HELRO
Uncharacterized protein
Search

0.52	Haloacid dehalogenase like hydrolase domain containing 5

0.68	GO:0046474	glycerophospholipid biosynthetic process
0.47	GO:0000350	generation of catalytic spliceosome for second transesterification step

0.58	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

tr|T1FP25|T1FP25_HELRO
Mothers against decapentaplegic homolog
Search

SMAD5

0.64	Mothers against decapentaplegic homolog

0.83	GO:0007179	transforming growth factor beta receptor signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0002051	osteoblast fate commitment
0.55	GO:0030099	myeloid cell differentiation
0.53	GO:0071773	cellular response to BMP stimulus
0.53	GO:0045669	positive regulation of osteoblast differentiation
0.53	GO:0060395	SMAD protein signal transduction

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.54	GO:0017151	DEAD/H-box RNA helicase binding
0.50	GO:0031625	ubiquitin protein ligase binding
0.48	GO:0001067	regulatory region nucleic acid binding
0.42	GO:0046982	protein heterodimerization activity
0.35	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
0.34	GO:0046872	metal ion binding

0.75	GO:0005667	transcription factor complex
0.61	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.45	GO:0070013	intracellular organelle lumen
0.41	GO:0044446	intracellular organelle part
0.35	GO:0071141	SMAD protein complex
0.30	GO:0016020	membrane

tr|T1FP26|T1FP26_HELRO
Uncharacterized protein
Search

CAD

0.70	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase

0.74	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process
0.68	GO:0006541	glutamine metabolic process
0.62	GO:0021644	vagus nerve morphogenesis
0.61	GO:0021615	glossopharyngeal nerve morphogenesis
0.61	GO:0021636	trigeminal nerve morphogenesis
0.60	GO:0021610	facial nerve morphogenesis
0.59	GO:1900746	regulation of vascular endothelial growth factor signaling pathway
0.59	GO:0001946	lymphangiogenesis
0.58	GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway
0.56	GO:0008593	regulation of Notch signaling pathway

0.79	GO:0004070	aspartate carbamoyltransferase activity
0.76	GO:0016597	amino acid binding
0.75	GO:0004088	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
0.75	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0046872	metal ion binding
0.54	GO:0004087	carbamoyl-phosphate synthase (ammonia) activity
0.35	GO:0042802	identical protein binding

0.38	GO:0005737	cytoplasm
0.36	GO:0016363	nuclear matrix
0.35	GO:0005654	nucleoplasm

0.79	EC:2.1.3.2	GO:0004070
0.79	KEGG:R01397	GO:0004070

tr|T1FP27|T1FP27_HELRO
Uncharacterized protein
Search

METTL13

0.78	Antiapoptotic protein FEAT

0.62	GO:0032259	methylation
0.34	GO:0006596	polyamine biosynthetic process

0.63	GO:0008168	methyltransferase activity
0.33	GO:0005515	protein binding

0.30

GO:0031224

intrinsic component of membrane

0.63

GO:0008168

tr|T1FP28|T1FP28_HELRO
Uncharacterized protein
Search

0.66	Unc-13 homolog B

0.78	GO:0007268	chemical synaptic transmission
0.62	GO:0035556	intracellular signal transduction
0.44	GO:0017156	calcium ion regulated exocytosis
0.44	GO:0097480	establishment of synaptic vesicle localization
0.44	GO:0099504	synaptic vesicle cycle
0.44	GO:0099003	vesicle-mediated transport in synapse
0.44	GO:0099643	signal release from synapse
0.42	GO:0006836	neurotransmitter transport
0.41	GO:0001505	regulation of neurotransmitter levels
0.41	GO:0046907	intracellular transport

0.85	GO:0019992	diacylglycerol binding
0.75	GO:0005543	phospholipid binding
0.70	GO:0005509	calcium ion binding
0.38	GO:0005516	calmodulin binding
0.37	GO:0030742	GTP-dependent protein binding

0.45	GO:0005622	intracellular
0.45	GO:0043195	terminal bouton
0.42	GO:0045211	postsynaptic membrane
0.38	GO:0031982	vesicle
0.37	GO:0012505	endomembrane system
0.36	GO:0048786	presynaptic active zone
0.35	GO:0097470	ribbon synapse
0.35	GO:0031594	neuromuscular junction
0.30	GO:0016021	integral component of membrane

tr|T1FP29|T1FP29_HELRO
Uncharacterized protein
Search

CDK6

0.68	Cell division protein kinase 6

0.63	GO:0006468	protein phosphorylation
0.61	GO:0043697	cell dedifferentiation
0.54	GO:0042127	regulation of cell proliferation
0.54	GO:0051726	regulation of cell cycle
0.50	GO:0007049	cell cycle
0.46	GO:0045656	negative regulation of monocyte differentiation
0.46	GO:1904628	cellular response to phorbol 13-acetate 12-myristate
0.46	GO:2000773	negative regulation of cellular senescence
0.45	GO:0003323	type B pancreatic cell development
0.45	GO:0045668	negative regulation of osteoblast differentiation

0.66	GO:0004674	protein serine/threonine kinase activity
0.60	GO:0097472	cyclin-dependent protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.48	GO:0030332	cyclin binding
0.47	GO:0098770	FBXO family protein binding
0.39	GO:0004540	ribonuclease activity
0.34	GO:0042803	protein homodimerization activity

0.48	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.44	GO:0001726	ruffle
0.42	GO:0005813	centrosome
0.41	GO:0005634	nucleus
0.40	GO:0070013	intracellular organelle lumen
0.40	GO:0005829	cytosol
0.36	GO:0072686	mitotic spindle
0.35	GO:0000785	chromatin
0.34	GO:0030176	integral component of endoplasmic reticulum membrane

0.66

GO:0004674

tr|T1FP30|T1FP30_HELRO
Uncharacterized protein
Search

0.10	Target of EGR1, member 1 (nuclear)

0.56	GO:0034472	snRNA 3'-end processing
0.52	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic
0.48	GO:0070050	neuron cellular homeostasis
0.45	GO:0007420	brain development

0.56	GO:0004535	poly(A)-specific ribonuclease activity
0.55	GO:0017069	snRNA binding
0.53	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.56	GO:0015030	Cajal body
0.40	GO:0016607	nuclear speck
0.39	GO:0005737	cytoplasm
0.38	GO:0005730	nucleolus

0.56

EC:3.1.13.4

GO:0004535

tr|T1FP31|T1FP31_HELRO
Uncharacterized protein
Search

TXNRD3

0.43	Thioredoxin reductase

0.68	GO:0098869	cellular oxidant detoxification
0.67	GO:0045454	cell redox homeostasis
0.59	GO:0022900	electron transport chain
0.43	GO:0000305	response to oxygen radical
0.39	GO:0001707	mesoderm formation
0.38	GO:0008283	cell proliferation
0.37	GO:0006749	glutathione metabolic process
0.36	GO:0007283	spermatogenesis
0.36	GO:0007507	heart development
0.35	GO:0030097	hemopoiesis

0.77	GO:0004791	thioredoxin-disulfide reductase activity
0.65	GO:0050660	flavin adenine dinucleotide binding
0.60	GO:0009055	electron transfer activity
0.58	GO:0015035	protein disulfide oxidoreductase activity
0.35	GO:0005515	protein binding

0.51	GO:0005829	cytosol
0.47	GO:0005654	nucleoplasm
0.44	GO:0005739	mitochondrion
0.39	GO:0001650	fibrillar center
0.35	GO:0005783	endoplasmic reticulum
0.34	GO:0043025	neuronal cell body
0.34	GO:0030425	dendrite
0.34	GO:0030424	axon
0.30	GO:0031224	intrinsic component of membrane

0.77	EC:1.8.1.9	GO:0004791
0.77	KEGG:R02016	GO:0004791

tr|T1FP32|T1FP32_HELRO
Arp2/3 complex 34 kDa subunit
Search

ARPC2

0.67	Actin-related protein 2/3 complex subunit 2

0.83	GO:0030041	actin filament polymerization
0.81	GO:0034314	Arp2/3 complex-mediated actin nucleation
0.50	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading
0.50	GO:0010592	positive regulation of lamellipodium assembly
0.40	GO:0030866	cortical actin cytoskeleton organization
0.38	GO:0000902	cell morphogenesis
0.38	GO:0030031	cell projection assembly
0.37	GO:0008360	regulation of cell shape
0.36	GO:1905924	regulation of invadopodium assembly
0.36	GO:2000814	positive regulation of barbed-end actin filament capping

0.73	GO:0003779	actin binding
0.49	GO:0005200	structural constituent of cytoskeleton
0.48	GO:0032403	protein complex binding
0.35	GO:0035254	glutamate receptor binding
0.35	GO:0051117	ATPase binding
0.35	GO:0019894	kinesin binding
0.33	GO:0004930	G-protein coupled receptor activity
0.33	GO:0016779	nucleotidyltransferase activity

0.80	GO:0005885	Arp2/3 protein complex
0.52	GO:0036195	muscle cell projection membrane
0.49	GO:0005737	cytoplasm
0.48	GO:0005925	focal adhesion
0.48	GO:0031252	cell leading edge
0.45	GO:0031982	vesicle
0.43	GO:0012505	endomembrane system
0.38	GO:0043005	neuron projection
0.38	GO:0045202	synapse
0.37	GO:0043230	extracellular organelle

0.33

GO:0016779

tr|T1FP33|T1FP33_HELRO
Adenosylhomocysteinase
Search

0.56	Adenosylhomocysteinase

0.72	GO:0006730	one-carbon metabolic process
0.40	GO:0042045	epithelial fluid transport
0.40	GO:0010765	positive regulation of sodium ion transport
0.39	GO:0038166	angiotensin-activated signaling pathway
0.39	GO:0031440	regulation of mRNA 3'-end processing
0.39	GO:0006611	protein export from nucleus
0.39	GO:0044070	regulation of anion transport
0.39	GO:0051592	response to calcium ion
0.39	GO:0032412	regulation of ion transmembrane transporter activity
0.38	GO:0006378	mRNA polyadenylation

0.80	GO:0004013	adenosylhomocysteinase activity
0.37	GO:0042802	identical protein binding
0.34	GO:0005125	cytokine activity
0.34	GO:0008083	growth factor activity

0.39	GO:0005829	cytosol
0.34	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016020	membrane

0.80

EC:3.3.1.1

GO:0004013

tr|T1FP34|T1FP34_HELRO
Secretory carrier-associated membrane protein
Search

0.67	Secretory carrier-associated membrane protein 3

0.65	GO:0015031	protein transport
0.34	GO:0032526	response to retinoic acid
0.33	GO:0046907	intracellular transport
0.33	GO:0034613	cellular protein localization
0.33	GO:0006468	protein phosphorylation

0.35	GO:0031625	ubiquitin protein ligase binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.34	GO:0000139	Golgi membrane
0.33	GO:0031410	cytoplasmic vesicle
0.30	GO:0031224	intrinsic component of membrane

tr|T1FP35|T1FP35_HELRO
Uncharacterized protein
Search

TAPT1

0.96	Transmembrane anterior posterior transformation protein 1

0.60	GO:0045724	positive regulation of cilium assembly
0.52	GO:0048706	embryonic skeletal system development
0.50	GO:0009791	post-embryonic development
0.50	GO:0001701	in utero embryonic development
0.50	GO:1903012	positive regulation of bone development
0.48	GO:0061036	positive regulation of cartilage development
0.48	GO:0014032	neural crest cell development
0.47	GO:0001503	ossification
0.45	GO:1904888	cranial skeletal system development
0.40	GO:0051216	cartilage development

0.35

GO:0016520

growth hormone-releasing hormone receptor activity

0.53	GO:0036064	ciliary basal body
0.51	GO:0005813	centrosome
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1FP36|T1FP36_HELRO
Uncharacterized protein
Search

EXT2

0.90	Exostosin glycosyltransferase 2

0.85	GO:0015012	heparan sulfate proteoglycan biosynthetic process
0.74	GO:0006486	protein glycosylation
0.69	GO:0006024	glycosaminoglycan biosynthetic process
0.55	GO:0001503	ossification
0.53	GO:0048598	embryonic morphogenesis
0.51	GO:0009888	tissue development
0.50	GO:0030154	cell differentiation
0.47	GO:0048646	anatomical structure formation involved in morphogenesis
0.47	GO:0035138	pectoral fin morphogenesis
0.47	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway

0.82	GO:0015020	glucuronosyltransferase activity
0.49	GO:0008375	acetylglucosaminyltransferase activity
0.47	GO:0042803	protein homodimerization activity
0.47	GO:0046982	protein heterodimerization activity
0.34	GO:0030170	pyridoxal phosphate binding
0.33	GO:0046872	metal ion binding

0.53	GO:0043541	UDP-N-acetylglucosamine transferase complex
0.46	GO:0005794	Golgi apparatus
0.36	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.36	GO:0098588	bounding membrane of organelle
0.30	GO:0016021	integral component of membrane

0.82

EC:2.4.1.17

GO:0015020

tr|T1FP37|T1FP37_HELRO
Uncharacterized protein
Search

0.12	Ubiquitin-associated domain-containing protein 2

0.43	GO:0016567	protein ubiquitination
0.39	GO:1904153	negative regulation of retrograde protein transport, ER to cytosol
0.38	GO:0006508	proteolysis
0.37	GO:0070972	protein localization to endoplasmic reticulum
0.35	GO:0043632	modification-dependent macromolecule catabolic process
0.35	GO:0044257	cellular protein catabolic process
0.35	GO:0035278	miRNA mediated inhibition of translation
0.34	GO:0006289	nucleotide-excision repair
0.32	GO:0055114	oxidation-reduction process

0.43	GO:0004842	ubiquitin-protein transferase activity
0.41	GO:0043130	ubiquitin binding
0.38	GO:0004252	serine-type endopeptidase activity
0.35	GO:0016874	ligase activity
0.34	GO:0003684	damaged DNA binding
0.34	GO:0061659	ubiquitin-like protein ligase activity
0.33	GO:0008270	zinc ion binding
0.32	GO:0016491	oxidoreductase activity

0.36	GO:0005783	endoplasmic reticulum
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.38	EC:3.4.21	GO:0004252
0.43	KEGG:R03876	GO:0004842

tr|T1FP38|T1FP38_HELRO
Uncharacterized protein
Search

0.67	GO:0006397	mRNA processing
0.45	GO:0007319	negative regulation of oskar mRNA translation
0.45	GO:0008103	oocyte microtubule cytoskeleton polarization
0.44	GO:0008586	imaginal disc-derived wing vein morphogenesis
0.44	GO:0007291	sperm individualization
0.44	GO:0008587	imaginal disc-derived wing margin morphogenesis
0.38	GO:0045595	regulation of cell differentiation
0.35	GO:0060470	positive regulation of cytosolic calcium ion concentration involved in egg activation
0.35	GO:0060729	intestinal epithelial structure maintenance
0.35	GO:0075522	IRES-dependent viral translational initiation

0.59	GO:0003723	RNA binding
0.44	GO:0000900	translation repressor activity, nucleic acid binding
0.36	GO:0032440	2-alkenal reductase [NAD(P)] activity

0.59	GO:0005634	nucleus
0.38	GO:0005829	cytosol
0.37	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016020	membrane

0.36

EC:1.3.1.74

GO:0032440

tr|T1FP39|T1FP39_HELRO
Protein kinase C
Search

PRKCZ

0.92	Protein kinase C zeta type

0.63	GO:0006468	protein phosphorylation
0.57	GO:0007163	establishment or maintenance of cell polarity
0.55	GO:2001181	positive regulation of interleukin-10 secretion
0.55	GO:2000667	positive regulation of interleukin-13 secretion
0.55	GO:0045630	positive regulation of T-helper 2 cell differentiation
0.55	GO:2000664	positive regulation of interleukin-5 secretion
0.55	GO:2000553	positive regulation of T-helper 2 cell cytokine production
0.53	GO:0032753	positive regulation of interleukin-4 production
0.52	GO:0035556	intracellular signal transduction
0.52	GO:1990138	neuron projection extension

0.70	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0046872	metal ion binding

0.54	GO:0035748	myelin sheath abaxonal region
0.54	GO:0043203	axon hillock
0.53	GO:0045179	apical cortex
0.52	GO:0016363	nuclear matrix
0.50	GO:0016324	apical plasma membrane
0.50	GO:0005923	bicellular tight junction
0.48	GO:0005635	nuclear envelope
0.48	GO:0005815	microtubule organizing center
0.47	GO:0031982	vesicle
0.43	GO:0005829	cytosol

0.70

GO:0004674

tr|T1FP40|T1FP40_HELRO
Nucleoside diphosphate kinase
Search

NDK

0.46	Nucleoside diphosphate kinase A

0.79	GO:0006228	UTP biosynthetic process
0.78	GO:0006183	GTP biosynthetic process
0.75	GO:0046036	CTP metabolic process
0.70	GO:0006165	nucleoside diphosphate phosphorylation
0.45	GO:0007595	lactation
0.44	GO:0050679	positive regulation of epithelial cell proliferation
0.44	GO:0043388	positive regulation of DNA binding
0.40	GO:0033574	response to testosterone
0.40	GO:0014075	response to amine
0.40	GO:0002762	negative regulation of myeloid leukocyte differentiation

0.79	GO:0004550	nucleoside diphosphate kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0046872	metal ion binding
0.44	GO:0043024	ribosomal small subunit binding
0.41	GO:0042802	identical protein binding
0.40	GO:0004536	deoxyribonuclease activity
0.40	GO:0019215	intermediate filament binding

0.44	GO:0001726	ruffle
0.44	GO:0005737	cytoplasm
0.43	GO:0031256	leading edge membrane
0.43	GO:0043209	myelin sheath
0.43	GO:0031253	cell projection membrane
0.39	GO:0005634	nucleus
0.38	GO:0005882	intermediate filament
0.38	GO:0005813	centrosome
0.38	GO:0031968	organelle outer membrane
0.36	GO:0005615	extracellular space

0.79

EC:2.7.4.6

GO:0004550

tr|T1FP41|T1FP41_HELRO
Uncharacterized protein
Search

0.61	Major heat shock 70 kDa protein Bbb

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0044425

membrane part

tr|T1FP42|T1FP42_HELRO
Uncharacterized protein
Search

PGM1

0.45	Phosphoglucomutase (inferred by orthology to a D. melanogaster protein)

0.60	GO:0005975	carbohydrate metabolic process
0.41	GO:0006112	energy reserve metabolic process
0.39	GO:0044282	small molecule catabolic process
0.38	GO:1901575	organic substance catabolic process
0.36	GO:0009059	macromolecule biosynthetic process
0.35	GO:0044260	cellular macromolecule metabolic process
0.35	GO:0044249	cellular biosynthetic process
0.34	GO:0032496	response to lipopolysaccharide
0.34	GO:0030239	myofibril assembly
0.34	GO:0014706	striated muscle tissue development

0.74	GO:0016868	intramolecular transferase activity, phosphotransferases
0.64	GO:0000287	magnesium ion binding
0.36	GO:0005509	calcium ion binding

0.39	GO:0005829	cytosol
0.38	GO:0015629	actin cytoskeleton
0.30	GO:0016020	membrane

0.74

EC:5.4.2

GO:0016868

tr|T1FP43|T1FP43_HELRO
Uncharacterized protein
Search

FAHD1

0.44	Fumarylacetoacetate hydrolase domain-containing protein 1

0.40	GO:1901023	4-hydroxyphenylacetate catabolic process
0.34	GO:0009439	cyanate metabolic process
0.32	GO:0016310	phosphorylation

0.43	GO:0016853	isomerase activity
0.41	GO:0018800	5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase activity
0.39	GO:0016787	hydrolase activity
0.36	GO:0050385	ureidoglycolate lyase activity
0.35	GO:0005507	copper ion binding
0.35	GO:0008948	oxaloacetate decarboxylase activity
0.34	GO:0008824	cyanate hydratase activity
0.32	GO:0043565	sequence-specific DNA binding
0.32	GO:0016301	kinase activity

0.35	GO:0005739	mitochondrion
0.34	GO:0005829	cytosol
0.34	GO:0005654	nucleoplasm
0.33	GO:0019866	organelle inner membrane

0.43	EC:5	GO:0016853
0.36	KEGG:R00776	GO:0050385

tr|T1FP44|T1FP44_HELRO
Uncharacterized protein
Search

0.55	Tyrosine-protein kinase

0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.38	GO:0060465	pharynx development
0.35	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.35	GO:0042127	regulation of cell proliferation
0.35	GO:0046777	protein autophosphorylation
0.35	GO:0045087	innate immune response
0.34	GO:0016477	cell migration
0.34	GO:0030154	cell differentiation
0.33	GO:0044344	cellular response to fibroblast growth factor stimulus
0.33	GO:0035556	intracellular signal transduction

0.77	GO:0004713	protein tyrosine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0019199	transmembrane receptor protein kinase activity
0.34	GO:0005102	receptor binding
0.32	GO:0004252	serine-type endopeptidase activity
0.31	GO:0016491	oxidoreductase activity

0.35	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.33	GO:0005856	cytoskeleton
0.30	GO:0016021	integral component of membrane

0.77

GO:0004713

tr|T1FP45|T1FP45_HELRO
Uncharacterized protein
Search

0.29	Non-specific protein-tyrosine kinase

0.72	GO:0018108	peptidyl-tyrosine phosphorylation
0.40	GO:0046777	protein autophosphorylation
0.40	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.39	GO:0045087	innate immune response
0.38	GO:0042127	regulation of cell proliferation
0.38	GO:0030154	cell differentiation
0.37	GO:0016477	cell migration

0.74	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.52	GO:0032559	adenyl ribonucleotide binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0005102	receptor binding
0.35	GO:0004714	transmembrane receptor protein tyrosine kinase activity

0.39	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.74

EC:2.7.10.2

GO:0004715

tr|T1FP46|T1FP46_HELRO
Uncharacterized protein
Search

CCNYL1

0.75	Cyclin Y like 1

0.80	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity
0.49	GO:0030317	flagellated sperm motility
0.47	GO:0007283	spermatogenesis

0.78

GO:0019901

protein kinase binding

0.39	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1FP47|T1FP47_HELRO
Uncharacterized protein
Search

PARVA

0.85	LOW QUALITY PROTEIN: alpha-parvin

0.77	GO:0031532	actin cytoskeleton reorganization
0.72	GO:0007155	cell adhesion
0.52	GO:0071670	smooth muscle cell chemotaxis
0.50	GO:0007163	establishment or maintenance of cell polarity
0.49	GO:0003148	outflow tract septum morphogenesis
0.49	GO:0070252	actin-mediated cell contraction
0.49	GO:0002040	sprouting angiogenesis
0.46	GO:0000904	cell morphogenesis involved in differentiation
0.44	GO:0030032	lamellipodium assembly
0.40	GO:0008360	regulation of cell shape

0.74	GO:0003779	actin binding
0.36	GO:0045296	cadherin binding
0.34	GO:0019904	protein domain specific binding
0.33	GO:0003700	DNA binding transcription factor activity
0.33	GO:0016301	kinase activity

0.52	GO:0005925	focal adhesion
0.51	GO:0030027	lamellipodium
0.45	GO:0015629	actin cytoskeleton
0.43	GO:0005829	cytosol
0.40	GO:0005634	nucleus
0.38	GO:0030018	Z disc
0.33	GO:0005886	plasma membrane
0.32	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

tr|T1FP48|T1FP48_HELRO
Fructose-bisphosphate aldolase
Search

0.53	Fructose-bisphosphate aldolase class-I

0.70	GO:0006757	ATP generation from ADP
0.69	GO:0006090	pyruvate metabolic process
0.68	GO:0016052	carbohydrate catabolic process
0.67	GO:0019362	pyridine nucleotide metabolic process
0.34	GO:0007498	mesoderm development
0.34	GO:0042593	glucose homeostasis

0.79	GO:0004332	fructose-bisphosphate aldolase activity
0.32	GO:0003677	DNA binding

0.35	GO:0031430	M band
0.34	GO:0030018	Z disc
0.33	GO:0005829	cytosol
0.33	GO:0000786	nucleosome

0.79

EC:4.1.2.13

GO:0004332

tr|T1FP49|T1FP49_HELRO
Tubulin beta chain
Search

0.49	Tubulin beta chain

0.72	GO:0007017	microtubule-based process
0.71	GO:0007010	cytoskeleton organization
0.48	GO:0007435	salivary gland morphogenesis
0.35	GO:0070925	organelle assembly
0.34	GO:0022402	cell cycle process

0.77	GO:0005200	structural constituent of cytoskeleton
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0042288	MHC class I protein binding
0.35	GO:0031625	ubiquitin protein ligase binding

0.73	GO:0005874	microtubule
0.45	GO:0005737	cytoplasm
0.36	GO:0005641	nuclear envelope lumen
0.35	GO:0044297	cell body
0.35	GO:0035770	ribonucleoprotein granule
0.30	GO:0016020	membrane

tr|T1FP50|T1FP50_HELRO
Uncharacterized protein
Search

RBPJ

0.90	Recombination signal binding protein for immunoglobulin kappa J region

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.53	GO:1905068	positive regulation of canonical Wnt signaling pathway involved in heart development
0.53	GO:1901189	positive regulation of ephrin receptor signaling pathway
0.52	GO:0097101	blood vessel endothelial cell fate specification
0.52	GO:1901295	regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment
0.52	GO:0060844	arterial endothelial cell fate commitment
0.52	GO:0060486	Clara cell differentiation
0.52	GO:0072554	blood vessel lumenization
0.52	GO:0072602	interleukin-4 secretion
0.51	GO:0009957	epidermal cell fate specification

0.80	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.80	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.51	GO:0001103	RNA polymerase II repressing transcription factor binding
0.49	GO:0047485	protein N-terminus binding
0.49	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.46	GO:0003682	chromatin binding
0.34	GO:0032403	protein complex binding
0.34	GO:0000150	recombinase activity

0.61	GO:0005634	nucleus
0.53	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex
0.49	GO:0017053	transcriptional repressor complex
0.45	GO:0005667	transcription factor complex
0.44	GO:0070013	intracellular organelle lumen
0.41	GO:0043232	intracellular non-membrane-bounded organelle
0.40	GO:0044446	intracellular organelle part
0.37	GO:0005737	cytoplasm
0.33	GO:0032993	protein-DNA complex
0.30	GO:0016020	membrane

tr|T1FP51|T1FP51_HELRO
Uncharacterized protein
Search

0.27	RNA-binding protein cabeza

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.37	GO:0009303	rRNA transcription
0.37	GO:0001947	heart looping
0.36	GO:0006364	rRNA processing
0.35	GO:0001522	pseudouridine synthesis
0.34	GO:0006414	translational elongation
0.34	GO:0006281	DNA repair
0.33	GO:0016074	snoRNA metabolic process

0.58	GO:0003723	RNA binding
0.52	GO:0046872	metal ion binding
0.34	GO:0008094	DNA-dependent ATPase activity
0.34	GO:0003677	DNA binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0004386	helicase activity
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0009982	pseudouridine synthase activity
0.33	GO:0008168	methyltransferase activity

0.35	GO:0031429	box H/ACA snoRNP complex
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.33

EC:5.4.99.12

GO:0009982

tr|T1FP52|T1FP52_HELRO
Uncharacterized protein
Search

0.63	Eukaryotic translation initiation factor 2C 2

0.45	GO:0035073	pupariation
0.38	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.38	GO:0002181	cytoplasmic translation
0.37	GO:0000387	spliceosomal snRNP assembly
0.35	GO:0006413	translational initiation
0.34	GO:0007076	mitotic chromosome condensation

0.36	GO:0003723	RNA binding
0.35	GO:0003735	structural constituent of ribosome

0.57	GO:0005840	ribosome
0.37	GO:0044445	cytosolic part
0.36	GO:0005681	spliceosomal complex
0.34	GO:0000796	condensin complex
0.30	GO:0016020	membrane

tr|T1FP53|T1FP53_HELRO
Uncharacterized protein
Search

DDX46

0.91	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46

0.55	GO:0010501	RNA secondary structure unwinding
0.51	GO:0000398	mRNA splicing, via spliceosome
0.42	GO:0060255	regulation of macromolecule metabolic process

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0004004	ATP-dependent RNA helicase activity
0.51	GO:0003676	nucleic acid binding

0.66	GO:0001650	fibrillar center
0.64	GO:0016607	nuclear speck
0.39	GO:0005737	cytoplasm

tr|T1FP54|T1FP54_HELRO
Uncharacterized protein
Search

0.60	Serine/threonine protein phosphatase 2A regulatory subunit

0.79	GO:0043666	regulation of phosphoprotein phosphatase activity
0.61	GO:0007165	signal transduction
0.42	GO:0008340	determination of adult lifespan
0.41	GO:1903863	P granule assembly
0.40	GO:0009966	regulation of signal transduction
0.40	GO:0040024	dauer larval development
0.40	GO:0048523	negative regulation of cellular process
0.39	GO:0023056	positive regulation of signaling
0.39	GO:0010647	positive regulation of cell communication
0.39	GO:0010883	regulation of lipid storage

0.80	GO:0019888	protein phosphatase regulator activity
0.39	GO:0019211	phosphatase activator activity
0.38	GO:0019901	protein kinase binding
0.38	GO:0004722	protein serine/threonine phosphatase activity
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0032561	guanyl ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.81	GO:0000159	protein phosphatase type 2A complex
0.37	GO:0005829	cytosol
0.30	GO:0016020	membrane

tr|T1FP55|T1FP55_HELRO
V-type proton ATPase subunit a
Search

0.43	V-type proton ATPase subunit a

0.76	GO:0015991	ATP hydrolysis coupled proton transport
0.50	GO:0070482	response to oxygen levels
0.48	GO:0007035	vacuolar acidification
0.47	GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly
0.46	GO:0002119	nematode larval development
0.44	GO:0007271	synaptic transmission, cholinergic
0.44	GO:0006879	cellular iron ion homeostasis
0.43	GO:0050830	defense response to Gram-positive bacterium
0.43	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.43	GO:0006754	ATP biosynthetic process

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.47	GO:0051117	ATPase binding
0.46	GO:0036442	proton-exporting ATPase activity
0.43	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
0.36	GO:0004788	thiamine diphosphokinase activity
0.36	GO:0030975	thiamine binding
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0097367	carbohydrate derivative binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0004791	thioredoxin-disulfide reductase activity

0.79	GO:0033179	proton-transporting V-type ATPase, V0 domain
0.71	GO:0044437	vacuolar part
0.47	GO:0098805	whole membrane
0.46	GO:0098588	bounding membrane of organelle
0.46	GO:0001669	acrosomal vesicle
0.39	GO:0016324	apical plasma membrane
0.37	GO:0000323	lytic vacuole
0.35	GO:0044440	endosomal part
0.34	GO:0045335	phagocytic vesicle
0.33	GO:0000322	storage vacuole

0.36	EC:2.7.6.2	GO:0004788
0.33	KEGG:R02016	GO:0004791

tr|T1FP56|T1FP56_HELRO
Uncharacterized protein
Search

SLC2A1

0.82	Glucose transporter type 1

0.70	GO:1904659	glucose transmembrane transport
0.51	GO:0070837	dehydroascorbic acid transport
0.50	GO:0071548	response to dexamethasone
0.50	GO:0032868	response to insulin
0.48	GO:0042149	cellular response to glucose starvation
0.45	GO:0006461	protein complex assembly
0.39	GO:1904016	response to Thyroglobulin triiodothyronine
0.38	GO:0010827	regulation of glucose transport
0.38	GO:0071470	cellular response to osmotic stress
0.38	GO:0048731	system development

0.70	GO:0005355	glucose transmembrane transporter activity
0.51	GO:0043621	protein self-association
0.51	GO:0033300	dehydroascorbic acid transmembrane transporter activity
0.45	GO:0042802	identical protein binding
0.37	GO:0042910	xenobiotic transmembrane transporter activity
0.37	GO:0019900	kinase binding
0.34	GO:0005536	glucose binding
0.32	GO:0003676	nucleic acid binding

0.49	GO:0001939	female pronucleus
0.49	GO:0030864	cortical actin cytoskeleton
0.48	GO:0030496	midbody
0.47	GO:0016323	basolateral plasma membrane
0.47	GO:0045121	membrane raft
0.46	GO:0016324	apical plasma membrane
0.45	GO:0031982	vesicle
0.44	GO:0005887	integral component of plasma membrane
0.43	GO:0005829	cytosol
0.38	GO:0042383	sarcolemma

tr|T1FP57|T1FP57_HELRO
Uncharacterized protein
Search

STXBP1

0.87	Neural-specific syntaxin-binding protein 1

0.80	GO:0006904	vesicle docking involved in exocytosis
0.44	GO:0099643	signal release from synapse
0.44	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.43	GO:0007317	regulation of pole plasm oskar mRNA localization
0.43	GO:0048468	cell development
0.42	GO:0006836	neurotransmitter transport
0.42	GO:0002576	platelet degranulation
0.42	GO:1900006	positive regulation of dendrite development
0.42	GO:0070527	platelet aggregation
0.41	GO:0001505	regulation of neurotransmitter levels

0.42	GO:0017075	syntaxin-1 binding
0.32	GO:0022857	transmembrane transporter activity

0.44	GO:0030424	axon
0.43	GO:0098793	presynapse
0.42	GO:0005829	cytosol
0.42	GO:0031091	platelet alpha granule
0.42	GO:0044306	neuron projection terminus
0.40	GO:0019898	extrinsic component of membrane
0.39	GO:0045335	phagocytic vesicle
0.39	GO:0043209	myelin sheath
0.39	GO:0097060	synaptic membrane
0.38	GO:0005654	nucleoplasm

tr|T1FP58|T1FP58_HELRO
Uncharacterized protein
Search

0.80	Alpha-actinin, sarcomeric

0.35	GO:0051017	actin filament bundle assembly
0.34	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:0035335	peptidyl-tyrosine dephosphorylation

0.74	GO:0003779	actin binding
0.69	GO:0005509	calcium ion binding
0.35	GO:0019863	IgE binding
0.34	GO:0004930	G-protein coupled receptor activity
0.33	GO:0004725	protein tyrosine phosphatase activity

0.30

GO:0016021

integral component of membrane

0.33

GO:0004725

tr|T1FP59|T1FP59_HELRO
Uncharacterized protein
Search

0.56	GO:0006368	transcription elongation from RNA polymerase II promoter
0.53	GO:0016570	histone modification
0.51	GO:2001141	regulation of RNA biosynthetic process
0.50	GO:0043001	Golgi to plasma membrane protein transport

0.69	GO:0003713	transcription coactivator activity
0.51	GO:0035254	glutamate receptor binding
0.50	GO:0030165	PDZ domain binding
0.43	GO:0003677	DNA binding
0.38	GO:0016787	hydrolase activity

0.59	GO:0005634	nucleus
0.53	GO:0000428	DNA-directed RNA polymerase complex
0.50	GO:0030672	synaptic vesicle membrane
0.49	GO:0031974	membrane-enclosed lumen
0.48	GO:0030425	dendrite
0.48	GO:0005802	trans-Golgi network
0.45	GO:0043234	protein complex

0.38

GO:0016787

tr|T1FP60|T1FP60_HELRO
V-type proton ATPase subunit a
Search

0.52	V-type proton ATPase subunit a

0.76	GO:0015991	ATP hydrolysis coupled proton transport
0.46	GO:0051452	intracellular pH reduction
0.43	GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly
0.42	GO:0007430	terminal branching, open tracheal system
0.41	GO:0097352	autophagosome maturation
0.40	GO:0048749	compound eye development
0.39	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.39	GO:0006754	ATP biosynthetic process
0.39	GO:0009416	response to light stimulus
0.38	GO:0007032	endosome organization

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.43	GO:0051117	ATPase binding
0.43	GO:0036442	proton-exporting ATPase activity
0.41	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
0.39	GO:0009881	photoreceptor activity
0.39	GO:0005516	calmodulin binding
0.34	GO:0015662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism

0.80	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain
0.42	GO:0016471	vacuolar proton-transporting V-type ATPase complex
0.41	GO:0070382	exocytic vesicle
0.41	GO:0005768	endosome
0.39	GO:0098793	presynapse
0.38	GO:0016324	apical plasma membrane
0.37	GO:0044298	cell body membrane
0.36	GO:0031526	brush border membrane
0.30	GO:0016021	integral component of membrane

tr|T1FP61|T1FP61_HELRO
Uncharacterized protein
Search

0.40	Developmentally-regulated GTP-binding protein 1

0.33	GO:0007275	multicellular organism development
0.32	GO:0006351	transcription, DNA-templated

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0042802	identical protein binding
0.33	GO:0008134	transcription factor binding

0.46	GO:0005844	polysome
0.45	GO:0016604	nuclear body
0.42	GO:0005829	cytosol
0.35	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

tr|T1FP62|T1FP62_HELRO
Sodium/potassium-transporting ATPase subunit alpha
Search

0.40	Sodium/potassium-transporting ATPase subunit alpha

0.80	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient
0.72	GO:0090662	ATP hydrolysis coupled transmembrane transport
0.69	GO:0006814	sodium ion transport
0.68	GO:0006813	potassium ion transport
0.47	GO:0042538	hyperosmotic salinity response
0.47	GO:0060416	response to growth hormone

0.80	GO:0005391	sodium:potassium-exchanging ATPase activity
0.53	GO:0030554	adenyl nucleotide binding
0.52	GO:0097367	carbohydrate derivative binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0046872	metal ion binding

0.30

GO:0016020

membrane

0.80

EC:3.6.3.9

GO:0005391

tr|T1FP63|T1FP63_HELRO
Uncharacterized protein
Search

0.55	GO:0055085	transmembrane transport
0.47	GO:1901998	toxin transport
0.44	GO:0042221	response to chemical
0.42	GO:0015031	protein transport
0.34	GO:0042908	xenobiotic transport
0.34	GO:0002790	peptide secretion
0.34	GO:0032940	secretion by cell
0.33	GO:0006508	proteolysis

0.66	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0019534	toxin transmembrane transporter activity
0.45	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
0.45	GO:0015562	efflux transmembrane transporter activity
0.34	GO:0042910	xenobiotic transmembrane transporter activity
0.33	GO:0015238	drug transmembrane transporter activity
0.33	GO:0008233	peptidase activity

0.40	GO:0000324	fungal-type vacuole
0.36	GO:0005886	plasma membrane
0.35	GO:0030256	type I protein secretion system complex
0.30	GO:0016021	integral component of membrane

0.33

GO:0008233

tr|T1FP64|T1FP64_HELRO
Uncharacterized protein
Search

NUP54

0.95	Putative nucleoporin p54 strongylocentrotus purpuratus

0.47	GO:0036228	protein localization to nuclear inner membrane
0.46	GO:0006607	NLS-bearing protein import into nucleus
0.46	GO:0006999	nuclear pore organization
0.36	GO:0007077	mitotic nuclear envelope disassembly
0.36	GO:0070208	protein heterotrimerization
0.36	GO:1900034	regulation of cellular response to heat
0.36	GO:0051290	protein heterotetramerization
0.36	GO:0071431	tRNA-containing ribonucleoprotein complex export from nucleus
0.36	GO:0006110	regulation of glycolytic process
0.36	GO:0051031	tRNA transport

0.44	GO:0017056	structural constituent of nuclear pore
0.34	GO:0004872	receptor activity
0.33	GO:0005515	protein binding

0.73	GO:0005643	nuclear pore
0.36	GO:0005764	lysosome
0.35	GO:0031965	nuclear membrane
0.33	GO:0043657	host cell
0.30	GO:0016021	integral component of membrane

tr|T1FP65|T1FP65_HELRO
Uncharacterized protein
Search

DHRS1

0.32	Short-chain dehydrogenase

0.51	GO:0097502	mannosylation
0.49	GO:0006486	protein glycosylation
0.48	GO:0055114	oxidation-reduction process
0.32	GO:0071897	DNA biosynthetic process
0.32	GO:0006260	DNA replication

0.54	GO:0000033	alpha-1,3-mannosyltransferase activity
0.49	GO:0016491	oxidoreductase activity
0.38	GO:0004312	fatty acid synthase activity
0.32	GO:0003887	DNA-directed DNA polymerase activity
0.32	GO:0003677	DNA binding

0.42	GO:0005783	endoplasmic reticulum
0.39	GO:0031966	mitochondrial membrane
0.39	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.54

GO:0000033

tr|T1FP66|T1FP66_HELRO
Uncharacterized protein
Search

0.63	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.42	GO:0006417	regulation of translation
0.35	GO:0043043	peptide biosynthetic process
0.34	GO:0044267	cellular protein metabolic process
0.34	GO:0009059	macromolecule biosynthetic process

0.38	GO:0003723	RNA binding
0.37	GO:0008146	sulfotransferase activity
0.36	GO:0005515	protein binding
0.36	GO:0003735	structural constituent of ribosome
0.35	GO:0016788	hydrolase activity, acting on ester bonds
0.34	GO:0008270	zinc ion binding

0.70	GO:0005730	nucleolus
0.61	GO:0032040	small-subunit processome
0.54	GO:0005739	mitochondrion
0.46	GO:0030175	filopodium
0.44	GO:0030425	dendrite
0.44	GO:0030424	axon
0.43	GO:0000775	chromosome, centromeric region
0.43	GO:0005654	nucleoplasm
0.36	GO:0019013	viral nucleocapsid
0.35	GO:0005840	ribosome

0.37

EC:2.8.2

GO:0008146

tr|T1FP67|T1FP67_HELRO
Uncharacterized protein
Search

0.85	Preli domain-containing protein mitochondrial

0.45	GO:0015914	phospholipid transport
0.41	GO:2001247	positive regulation of phosphatidylcholine biosynthetic process
0.40	GO:0097035	regulation of membrane lipid distribution
0.39	GO:0032048	cardiolipin metabolic process
0.37	GO:0010917	negative regulation of mitochondrial membrane potential
0.37	GO:1901857	positive regulation of cellular respiration
0.37	GO:2001140	positive regulation of phospholipid transport
0.37	GO:0070234	positive regulation of T cell apoptotic process
0.36	GO:0090201	negative regulation of release of cytochrome c from mitochondria
0.36	GO:0001578	microtubule bundle formation

0.49	GO:1990050	phosphatidic acid transporter activity
0.35	GO:0008017	microtubule binding
0.34	GO:0008289	lipid binding

0.79	GO:0005758	mitochondrial intermembrane space
0.39	GO:0031314	extrinsic component of mitochondrial inner membrane
0.36	GO:0030061	mitochondrial crista
0.34	GO:0005856	cytoskeleton
0.34	GO:0005654	nucleoplasm
0.33	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

tr|T1FP68|T1FP68_HELRO
Calcium-transporting ATPase
Search

0.57	Calcium-transporting ATPase

0.77	GO:0070588	calcium ion transmembrane transport
0.69	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.44	GO:0006874	cellular calcium ion homeostasis
0.37	GO:0040010	positive regulation of growth rate
0.36	GO:0002119	nematode larval development
0.36	GO:0045807	positive regulation of endocytosis
0.35	GO:0040017	positive regulation of locomotion
0.35	GO:0009792	embryo development ending in birth or egg hatching
0.35	GO:0006897	endocytosis

0.81	GO:0005388	calcium-transporting ATPase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.36	GO:0005886	plasma membrane
0.32	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.81

EC:3.6.3.8

GO:0005388

tr|T1FP69|T1FP69_HELRO
Uncharacterized protein
Search

0.77	Disco-interacting protein 2 B-A

0.30

GO:0008152

metabolic process

0.39

GO:0050564

N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase activity

0.30

GO:0044425

membrane part

0.39	EC:6.3.2.26	GO:0050564
0.39	KEGG:R04870	GO:0050564

tr|T1FP70|T1FP70_HELRO
Uncharacterized protein
Search

tr|T1FP71|T1FP71_HELRO
Uncharacterized protein
Search

GCDH

0.49	Glutaryl-CoA dehydrogenaseserine-threonine

0.53	GO:0055114	oxidation-reduction process
0.46	GO:0009062	fatty acid catabolic process
0.46	GO:0030258	lipid modification
0.38	GO:0046949	fatty-acyl-CoA biosynthetic process
0.36	GO:0006568	tryptophan metabolic process
0.34	GO:0006554	lysine catabolic process

0.74	GO:0003995	acyl-CoA dehydrogenase activity
0.66	GO:0050660	flavin adenine dinucleotide binding
0.37	GO:0000062	fatty-acyl-CoA binding
0.33	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups

0.41	GO:0005739	mitochondrion
0.36	GO:0043233	organelle lumen
0.34	GO:0044446	intracellular organelle part
0.33	GO:0031090	organelle membrane
0.33	GO:0031975	envelope

0.74

EC:1.3.99.3

GO:0003995

tr|T1FP72|T1FP72_HELRO
Uncharacterized protein
Search

0.42	Guanine nucleotide-binding protein G alpha subunit

0.81	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.46	GO:0014045	establishment of endothelial blood-brain barrier
0.46	GO:0042595	behavioral response to starvation
0.45	GO:0060857	establishment of glial blood-brain barrier
0.45	GO:0061343	cell adhesion involved in heart morphogenesis
0.45	GO:0001737	establishment of imaginal disc-derived wing hair orientation
0.45	GO:0019991	septate junction assembly
0.45	GO:0007419	ventral cord development
0.45	GO:0032291	axon ensheathment in central nervous system
0.45	GO:0045886	negative regulation of synaptic growth at neuromuscular junction

0.81	GO:0031683	G-protein beta/gamma-subunit complex binding
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.64	GO:0004871	signal transducer activity
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0001664	G-protein coupled receptor binding
0.34	GO:0051428	peptide hormone receptor binding
0.34	GO:0046872	metal ion binding

0.51	GO:1905360	GTPase complex
0.51	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.45	GO:0098797	plasma membrane protein complex
0.45	GO:0030425	dendrite
0.45	GO:0044297	cell body
0.35	GO:0005829	cytosol
0.34	GO:0070062	extracellular exosome
0.33	GO:0005635	nuclear envelope
0.33	GO:0005783	endoplasmic reticulum
0.30	GO:0031224	intrinsic component of membrane

tr|T1FP73|T1FP73_HELRO
Uncharacterized protein
Search

SLC25A28

0.91	Mitochondrial iron transporter 1

0.56	GO:0048250	mitochondrial iron ion transport
0.50	GO:0034755	iron ion transmembrane transport
0.45	GO:0055072	iron ion homeostasis
0.45	GO:0043249	erythrocyte maturation
0.44	GO:0035162	embryonic hemopoiesis
0.34	GO:0015684	ferrous iron transport

0.50	GO:0005381	iron ion transmembrane transporter activity
0.34	GO:0072509	divalent inorganic cation transmembrane transporter activity

0.45	GO:0005739	mitochondrion
0.42	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1FP74|T1FP74_HELRO
Uncharacterized protein
Search

PREP

0.64	Prolyl endopeptidase

0.61	GO:0006508	proteolysis
0.33	GO:0006414	translational elongation
0.32	GO:1902600	hydrogen ion transmembrane transport
0.32	GO:0022900	electron transport chain

0.73	GO:0070008	serine-type exopeptidase activity
0.69	GO:0004252	serine-type endopeptidase activity
0.35	GO:0008234	cysteine-type peptidase activity
0.34	GO:0042277	peptide binding
0.33	GO:0003746	translation elongation factor activity
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.33	GO:0005515	protein binding
0.32	GO:0015002	heme-copper terminal oxidase activity

0.46	GO:0005829	cytosol
0.43	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.73

GO:0070008

tr|T1FP75|T1FP75_HELRO
Uncharacterized protein
Search

0.85	Small nuclear ribonucleoprotein-associated protein B'

0.45	GO:0000398	mRNA splicing, via spliceosome
0.37	GO:0009725	response to hormone
0.37	GO:0022618	ribonucleoprotein complex assembly
0.35	GO:0008213	protein alkylation
0.34	GO:0043414	macromolecule methylation

0.55	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.60	GO:0030529	intracellular ribonucleoprotein complex
0.59	GO:0019013	viral nucleocapsid
0.57	GO:0005634	nucleus
0.46	GO:0120114	Sm-like protein family complex
0.43	GO:0031974	membrane-enclosed lumen
0.42	GO:0044446	intracellular organelle part
0.41	GO:1902494	catalytic complex
0.36	GO:0005737	cytoplasm
0.35	GO:0043234	protein complex
0.30	GO:0016020	membrane

tr|T1FP76|T1FP76_HELRO
Uncharacterized protein
Search

GCH1

0.31	GTP cyclohydrolase 1

0.75	GO:0046654	tetrahydrofolate biosynthetic process
0.50	GO:0014916	regulation of lung blood pressure
0.50	GO:0046146	tetrahydrobiopterin metabolic process
0.49	GO:0034312	diol biosynthetic process
0.49	GO:0010460	positive regulation of heart rate
0.49	GO:0042416	dopamine biosynthetic process
0.48	GO:0051000	positive regulation of nitric-oxide synthase activity
0.48	GO:2000121	regulation of removal of superoxide radicals
0.48	GO:0050884	neuromuscular process controlling posture
0.47	GO:0034341	response to interferon-gamma

0.79	GO:0003934	GTP cyclohydrolase I activity
0.48	GO:0051019	mitogen-activated protein kinase binding
0.44	GO:0042803	protein homodimerization activity
0.43	GO:0060308	GTP cyclohydrolase I regulator activity
0.43	GO:0032550	purine ribonucleoside binding
0.43	GO:0019001	guanyl nucleotide binding
0.42	GO:0008270	zinc ion binding
0.42	GO:0003924	GTPase activity
0.40	GO:0030742	GTP-dependent protein binding
0.39	GO:0032555	purine ribonucleotide binding

0.49	GO:0005737	cytoplasm
0.46	GO:0031965	nuclear membrane
0.43	GO:0097708	intracellular vesicle
0.43	GO:0005654	nucleoplasm
0.40	GO:0043234	protein complex
0.34	GO:0044306	neuron projection terminus

0.79	EC:3.5.4.16	GO:0003934
0.79	KEGG:R00424	GO:0003934

tr|T1FP77|T1FP77_HELRO
Uncharacterized protein
Search

ACTR2

0.85	Actin-related protein 2 isoform b

0.81	GO:0034314	Arp2/3 complex-mediated actin nucleation
0.53	GO:0016344	meiotic chromosome movement towards spindle pole
0.51	GO:0033206	meiotic cytokinesis
0.50	GO:0071346	cellular response to interferon-gamma
0.50	GO:0008356	asymmetric cell division
0.50	GO:0051653	spindle localization
0.49	GO:0060271	cilium assembly
0.48	GO:0016482	cytosolic transport
0.48	GO:0007163	establishment or maintenance of cell polarity
0.40	GO:0050807	regulation of synapse organization

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0051015	actin filament binding
0.48	GO:0005200	structural constituent of cytoskeleton

0.80	GO:0005885	Arp2/3 protein complex
0.52	GO:0030478	actin cap
0.44	GO:0005829	cytosol
0.40	GO:0061825	podosome core
0.39	GO:0042995	cell projection
0.38	GO:0014069	postsynaptic density
0.38	GO:0031252	cell leading edge
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.35	GO:1904813	ficolin-1-rich granule lumen

tr|T1FP78|T1FP78_HELRO
Uncharacterized protein
Search

EFL1

0.71	Elongation factor Tu GTP-binding domain-containing protein 1

0.62	GO:0006414	translational elongation
0.50	GO:0042256	mature ribosome assembly
0.49	GO:0046039	GTP metabolic process

0.66	GO:0003924	GTPase activity
0.64	GO:0032550	purine ribonucleoside binding
0.64	GO:0019001	guanyl nucleotide binding
0.63	GO:0003746	translation elongation factor activity
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0043022	ribosome binding

0.30

GO:0016020

membrane

tr|T1FP79|T1FP79_HELRO
Uncharacterized protein
Search

XPO1

0.84	Exportin-1

0.68	GO:0006886	intracellular protein transport
0.56	GO:0006611	protein export from nucleus
0.55	GO:0046825	regulation of protein export from nucleus
0.54	GO:0033750	ribosome localization
0.53	GO:0071166	ribonucleoprotein complex localization
0.53	GO:0051169	nuclear transport
0.52	GO:0051656	establishment of organelle localization
0.52	GO:0010824	regulation of centrosome duplication
0.50	GO:0051236	establishment of RNA localization
0.50	GO:0050657	nucleic acid transport

0.79	GO:0008536	Ran GTPase binding
0.57	GO:0005049	nuclear export signal receptor activity
0.46	GO:0008565	protein transporter activity
0.36	GO:0019904	protein domain specific binding
0.36	GO:0005487	structural constituent of nuclear pore
0.34	GO:0003723	RNA binding

0.61	GO:0005634	nucleus
0.55	GO:0005642	annulate lamellae
0.50	GO:0000776	kinetochore
0.46	GO:0005829	cytosol
0.45	GO:0031974	membrane-enclosed lumen
0.43	GO:0031967	organelle envelope
0.43	GO:0031090	organelle membrane
0.43	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0044216	other organism cell
0.33	GO:0018995	host

tr|T1FP80|T1FP80_HELRO
Uncharacterized protein
Search

TM7SF2

0.75	Lamin B receptor

0.52	GO:0055114	oxidation-reduction process
0.48	GO:0016126	sterol biosynthetic process
0.39	GO:1902653	secondary alcohol biosynthetic process
0.38	GO:0042074	cell migration involved in gastrulation
0.37	GO:0008203	cholesterol metabolic process
0.36	GO:0008204	ergosterol metabolic process
0.36	GO:0044108	cellular alcohol biosynthetic process
0.36	GO:0016129	phytosteroid biosynthetic process
0.36	GO:0097384	cellular lipid biosynthetic process
0.35	GO:0045540	regulation of cholesterol biosynthetic process

0.73	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
0.43	GO:0070087	chromo shadow domain binding
0.36	GO:0050661	NADP binding
0.35	GO:0008139	nuclear localization sequence binding
0.34	GO:0051087	chaperone binding
0.33	GO:0003723	RNA binding
0.32	GO:0003677	DNA binding
0.32	GO:0046872	metal ion binding

0.50	GO:0031965	nuclear membrane
0.49	GO:0005783	endoplasmic reticulum
0.48	GO:0043235	receptor complex
0.44	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.43	GO:0031984	organelle subcompartment
0.42	GO:0019866	organelle inner membrane
0.36	GO:0031301	integral component of organelle membrane
0.34	GO:0005643	nuclear pore
0.33	GO:0005887	integral component of plasma membrane

0.73

EC:1.3.1

GO:0016628

tr|T1FP81|T1FP81_HELRO
Uncharacterized protein
Search

PPP1R13L

0.76	Apoptosis-stimulating of protein 2 (Fragment)

0.74	GO:0006915	apoptotic process
0.58	GO:0003215	cardiac right ventricle morphogenesis
0.57	GO:0031076	embryonic camera-type eye development
0.57	GO:0003229	ventricular cardiac muscle tissue development
0.57	GO:0042633	hair cycle
0.56	GO:0060048	cardiac muscle contraction
0.56	GO:0035264	multicellular organism growth
0.56	GO:0006351	transcription, DNA-templated
0.55	GO:0048871	multicellular organismal homeostasis
0.53	GO:0009791	post-embryonic development

0.69	GO:0008134	transcription factor binding
0.54	GO:0045296	cadherin binding
0.51	GO:0042802	identical protein binding
0.43	GO:0030296	protein tyrosine kinase activator activity
0.37	GO:0004003	ATP-dependent DNA helicase activity
0.36	GO:0102568	phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
0.36	GO:0102567	phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
0.36	GO:0004623	phospholipase A2 activity
0.36	GO:0003714	transcription corepressor activity
0.34	GO:0032559	adenyl ribonucleotide binding

0.57	GO:0045171	intercellular bridge
0.54	GO:0030054	cell junction
0.49	GO:0005829	cytosol
0.37	GO:0005634	nucleus
0.34	GO:0043233	organelle lumen
0.34	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.36

EC:3.1.1.4

GO:0004623

tr|T1FP82|T1FP82_HELRO
Uncharacterized protein
Search

BCKDHA

0.64	Branched chain alpha-keto acid dehydrogenase complex alpha subunit

0.80	GO:0009083	branched-chain amino acid catabolic process
0.53	GO:0055114	oxidation-reduction process
0.36	GO:0006275	regulation of DNA replication
0.35	GO:0006260	DNA replication
0.34	GO:0046949	fatty-acyl-CoA biosynthetic process
0.34	GO:0051591	response to cAMP
0.34	GO:0000413	protein peptidyl-prolyl isomerization
0.34	GO:0051384	response to glucocorticoid
0.34	GO:0007584	response to nutrient
0.34	GO:0006457	protein folding

0.83	GO:0003826	alpha-ketoacid dehydrogenase activity
0.82	GO:0003863	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity
0.37	GO:0030337	DNA polymerase processivity factor activity
0.35	GO:0047101	2-oxoisovalerate dehydrogenase (acylating) activity
0.34	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.34	GO:0046872	metal ion binding
0.34	GO:0032403	protein complex binding
0.33	GO:0003677	DNA binding

0.38	GO:0005759	mitochondrial matrix
0.36	GO:0098798	mitochondrial protein complex
0.35	GO:0045240	dihydrolipoyl dehydrogenase complex
0.34	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.82

EC:1.2.4.4

GO:0003863

tr|T1FP83|T1FP83_HELRO
Uncharacterized protein
Search

0.48	Haloacid dehalogenase like hydrolase domain containing 5

0.63

GO:0046474

glycerophospholipid biosynthetic process

0.36

GO:0016787

hydrolase activity

0.58	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.36

GO:0016787

tr|T1FP84|T1FP84_HELRO
Uncharacterized protein
Search

PSMD11

0.72	26S proteasome non-ATPase regulatory subunit

0.80	GO:0043248	proteasome assembly
0.54	GO:0048863	stem cell differentiation
0.50	GO:0006511	ubiquitin-dependent protein catabolic process
0.35	GO:0051347	positive regulation of transferase activity
0.35	GO:0010498	proteasomal protein catabolic process
0.35	GO:0031401	positive regulation of protein modification process
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.35	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway

0.40	GO:0005198	structural molecule activity
0.35	GO:0016534	cyclin-dependent protein kinase 5 activator activity
0.34	GO:0005515	protein binding

0.65	GO:1905369	endopeptidase complex
0.54	GO:0043234	protein complex
0.42	GO:0005622	intracellular
0.36	GO:0070062	extracellular exosome
0.35	GO:0031983	vesicle lumen
0.34	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex
0.33	GO:0012505	endomembrane system
0.30	GO:0016020	membrane

tr|T1FP85|T1FP85_HELRO
Uncharacterized protein
Search

0.43	Glyoxylate and hydroxypyruvate reductase

0.53	GO:0055114	oxidation-reduction process
0.34	GO:0007588	excretion
0.34	GO:0046487	glyoxylate metabolic process
0.34	GO:0044085	cellular component biogenesis
0.33	GO:0016072	rRNA metabolic process
0.33	GO:0071822	protein complex subunit organization
0.33	GO:0008033	tRNA processing
0.33	GO:0032259	methylation
0.33	GO:2001141	regulation of RNA biosynthetic process
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.68	GO:0051287	NAD binding
0.66	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
0.34	GO:0070402	NADPH binding
0.34	GO:0042803	protein homodimerization activity
0.33	GO:0008168	methyltransferase activity
0.33	GO:0003723	RNA binding

0.38	GO:0005829	cytosol
0.33	GO:0005634	nucleus

0.66

EC:1.1.1

GO:0016616

tr|T1FP86|T1FP86_HELRO
Uncharacterized protein
Search

TEKT3

0.95	Putative cystoskeletal protein tektin

0.76	GO:0030317	flagellated sperm motility
0.73	GO:0080154	regulation of fertilization
0.72	GO:0060271	cilium assembly
0.66	GO:0060294	cilium movement involved in cell motility
0.35	GO:0007165	signal transduction

0.36	GO:0003924	GTPase activity
0.35	GO:0032550	purine ribonucleoside binding
0.35	GO:0019001	guanyl nucleotide binding
0.35	GO:0005515	protein binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.72	GO:0036126	sperm flagellum
0.63	GO:0002080	acrosomal membrane
0.50	GO:0015630	microtubule cytoskeleton
0.49	GO:0005634	nucleus
0.43	GO:0099513	polymeric cytoskeletal fiber
0.40	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

tr|T1FP87|T1FP87_HELRO
Uncharacterized protein
Search

LOC108733709

0.76	5'-AMP-activated protein kinase subunit gamma-2

0.54	GO:0016310	phosphorylation
0.54	GO:0042595	behavioral response to starvation
0.54	GO:0030730	sequestering of triglyceride
0.51	GO:0042632	cholesterol homeostasis
0.49	GO:0045787	positive regulation of cell cycle
0.49	GO:0009267	cellular response to starvation
0.48	GO:0006914	autophagy
0.43	GO:0006629	lipid metabolic process

0.56	GO:0016301	kinase activity
0.45	GO:0019901	protein kinase binding

0.42	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|T1FP88|T1FP88_HELRO
Uncharacterized protein
Search

ELAV

0.79	RNA binding protein Gbfne

0.47	GO:0036093	germ cell proliferation
0.46	GO:0060856	establishment of blood-brain barrier
0.43	GO:0048477	oogenesis
0.43	GO:0031441	negative regulation of mRNA 3'-end processing
0.40	GO:0007417	central nervous system development
0.36	GO:0048646	anatomical structure formation involved in morphogenesis
0.34	GO:0007319	negative regulation of oskar mRNA translation
0.33	GO:0009792	embryo development ending in birth or egg hatching
0.32	GO:0055114	oxidation-reduction process

0.59	GO:0003723	RNA binding
0.34	GO:0000900	translation repressor activity, nucleic acid binding
0.32	GO:0016491	oxidoreductase activity

0.42	GO:0015030	Cajal body
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016491

tr|T1FP89|T1FP89_HELRO
Obg-like ATPase 1
Search

0.91	Putative gtp-binding protein odn superfamily (Fragment)

0.66

GO:0005525

GTP binding

tr|T1FP90|T1FP90_HELRO
Uncharacterized protein
Search

tr|T1FP91|T1FP91_HELRO
Uncharacterized protein
Search

ACTR10

0.95	Actin-related protein 10 homolog (S. cerevisiae)

0.70	GO:0007018	microtubule-based movement
0.61	GO:0051654	establishment of mitochondrion localization
0.58	GO:0030705	cytoskeleton-dependent intracellular transport
0.44	GO:0034314	Arp2/3 complex-mediated actin nucleation
0.41	GO:0010469	regulation of receptor activity
0.41	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.40	GO:0043312	neutrophil degranulation
0.39	GO:0006888	ER to Golgi vesicle-mediated transport
0.35	GO:0006338	chromatin remodeling
0.35	GO:0006511	ubiquitin-dependent protein catabolic process

0.42	GO:0008083	growth factor activity
0.38	GO:1901265	nucleoside phosphate binding
0.37	GO:0036094	small molecule binding
0.37	GO:0097367	carbohydrate derivative binding
0.37	GO:0008144	drug binding
0.37	GO:0043168	anion binding
0.35	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.33	GO:0070001	aspartic-type peptidase activity
0.33	GO:0004175	endopeptidase activity
0.33	GO:0004672	protein kinase activity

0.69	GO:0005869	dynactin complex
0.60	GO:1904115	axon cytoplasm
0.44	GO:0005885	Arp2/3 protein complex
0.41	GO:0005576	extracellular region
0.41	GO:1904813	ficolin-1-rich granule lumen
0.41	GO:0035578	azurophil granule lumen
0.37	GO:0005829	cytosol
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

tr|T1FP92|T1FP92_HELRO
Uncharacterized protein
Search

0.81

Vinculin

0.72	GO:0007155	cell adhesion
0.35	GO:0007016	cytoskeletal anchoring at plasma membrane

0.78	GO:0051015	actin filament binding
0.58	GO:0005198	structural molecule activity

0.69	GO:0015629	actin cytoskeleton
0.45	GO:0098592	cytoplasmic side of apical plasma membrane
0.34	GO:0005925	focal adhesion
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1FP93|T1FP93_HELRO
Uncharacterized protein
Search

0.55	Mitochondrial ornithine transporter

0.44	GO:0000066	mitochondrial ornithine transport
0.43	GO:1903352	L-ornithine transmembrane transport
0.39	GO:0006508	proteolysis
0.34	GO:0000050	urea cycle
0.34	GO:0006182	cGMP biosynthetic process
0.33	GO:0006310	DNA recombination

0.44	GO:0000064	L-ornithine transmembrane transporter activity
0.41	GO:0017171	serine hydrolase activity
0.40	GO:0070011	peptidase activity, acting on L-amino acid peptides
0.34	GO:0004383	guanylate cyclase activity
0.34	GO:0070035	purine NTP-dependent helicase activity
0.33	GO:0042623	ATPase activity, coupled
0.33	GO:0008270	zinc ion binding
0.33	GO:0003676	nucleic acid binding
0.33	GO:0020037	heme binding
0.32	GO:0032559	adenyl ribonucleotide binding

0.39	GO:0005739	mitochondrion
0.39	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:4.6.1.2

GO:0004383

tr|T1FP94|T1FP94_HELRO
Uncharacterized protein
Search

DNPEP

0.77	Aspartyl aminopeptidase

0.58	GO:0006508	proteolysis
0.40	GO:0061077	chaperone-mediated protein folding
0.39	GO:0006518	peptide metabolic process

0.67	GO:0004177	aminopeptidase activity
0.63	GO:0008237	metallopeptidase activity
0.60	GO:0008270	zinc ion binding
0.34	GO:0042802	identical protein binding

0.44	GO:0005829	cytosol
0.41	GO:0000328	fungal-type vacuole lumen
0.40	GO:0005576	extracellular region
0.33	GO:0005634	nucleus

0.67

EC:3.4.11

GO:0004177

tr|T1FP95|T1FP95_HELRO
Alpha-1,4 glucan phosphorylase
Search

0.51	Glycogen phosphorylase

0.60	GO:0005975	carbohydrate metabolic process
0.42	GO:0006112	energy reserve metabolic process
0.40	GO:0009057	macromolecule catabolic process
0.39	GO:0044248	cellular catabolic process
0.36	GO:0070266	necroptotic process
0.35	GO:0044260	cellular macromolecule metabolic process
0.35	GO:0042593	glucose homeostasis

0.80	GO:0102250	linear malto-oligosaccharide phosphorylase activity
0.80	GO:0102499	SHG alpha-glucan phosphorylase activity
0.80	GO:0008184	glycogen phosphorylase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.36	GO:0002060	purine nucleobase binding
0.36	GO:0032052	bile acid binding
0.35	GO:0016208	AMP binding
0.33	GO:0005524	ATP binding
0.32	GO:0016787	hydrolase activity

0.35	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.32

GO:0016787

tr|T1FP96|T1FP96_HELRO
Uncharacterized protein
Search

0.16	Metastasis-associated protein MTA1

0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression

0.77	GO:0003682	chromatin binding
0.65	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity

0.61

GO:0005634

nucleus

tr|T1FP97|T1FP97_HELRO
Uncharacterized protein
Search

0.57	Signal transducer and activator of transcription (Fragment)

0.75	GO:0046579	positive regulation of Ras protein signal transduction
0.52	GO:0032287	peripheral nervous system myelin maintenance
0.51	GO:0045576	mast cell activation
0.51	GO:0048538	thymus development
0.50	GO:0045580	regulation of T cell differentiation
0.47	GO:0042127	regulation of cell proliferation
0.39	GO:0007165	signal transduction

0.39

GO:0016787

hydrolase activity

0.35

GO:0005737

cytoplasm

0.39

GO:0016787

tr|T1FP98|T1FP98_HELRO
Uncharacterized protein
Search

0.51	Nucleoporin seh1

0.73	GO:1904263	positive regulation of TORC1 signaling
0.59	GO:0015031	protein transport
0.49	GO:1905499	trichome papilla formation
0.49	GO:0010091	trichome branching
0.48	GO:0009911	positive regulation of flower development
0.48	GO:0009867	jasmonic acid mediated signaling pathway
0.48	GO:0010114	response to red light
0.48	GO:0010218	response to far red light
0.47	GO:0009585	red, far-red light phototransduction
0.46	GO:0050832	defense response to fungus

0.70	GO:0017056	structural constituent of nuclear pore
0.40	GO:0003677	DNA binding
0.38	GO:0033204	ribonuclease P RNA binding
0.37	GO:0140110	transcription regulator activity
0.37	GO:0008143	poly(A) binding
0.36	GO:0008097	5S rRNA binding
0.36	GO:0140096	catalytic activity, acting on a protein
0.36	GO:0008312	7S RNA binding
0.36	GO:0005515	protein binding
0.35	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity

0.45	GO:0044451	nucleoplasm part
0.40	GO:0043234	protein complex
0.37	GO:1990234	transferase complex
0.36	GO:1905368	peptidase complex
0.35	GO:0005887	integral component of plasma membrane
0.35	GO:0030136	clathrin-coated vesicle
0.35	GO:0034705	potassium channel complex

0.35

EC:3.1.4.17

GO:0004114

tr|T1FP99|T1FP99_HELRO
Structural maintenance of chromosomes protein
Search

0.10	Putative structural maintenance (Fragment)

0.75	GO:0007064	mitotic sister chromatid cohesion
0.60	GO:0006281	DNA repair
0.54	GO:0072423	response to DNA damage checkpoint signaling
0.54	GO:0032876	negative regulation of DNA endoreduplication
0.53	GO:1901673	regulation of mitotic spindle assembly
0.51	GO:0019827	stem cell population maintenance
0.49	GO:0051321	meiotic cell cycle
0.49	GO:0009314	response to radiation
0.37	GO:0051301	cell division
0.36	GO:0048731	system development

0.70	GO:0003682	chromatin binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0036033	mediator complex binding
0.48	GO:0046982	protein heterodimerization activity
0.34	GO:0003723	RNA binding

0.77	GO:0008278	cohesin complex
0.59	GO:0005634	nucleus
0.53	GO:0097431	mitotic spindle pole
0.50	GO:0000776	kinetochore
0.45	GO:0005829	cytosol
0.45	GO:0031974	membrane-enclosed lumen
0.34	GO:0000779	condensed chromosome, centromeric region
0.30	GO:0031224	intrinsic component of membrane

tr|T1FPA0|T1FPA0_HELRO
Uncharacterized protein
Search

0.71	Casein kinase I

0.63	GO:0006468	protein phosphorylation
0.48	GO:2000052	positive regulation of non-canonical Wnt signaling pathway
0.48	GO:0032922	circadian regulation of gene expression
0.47	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.47	GO:0042752	regulation of circadian rhythm
0.46	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.46	GO:0018209	peptidyl-serine modification
0.44	GO:0016055	Wnt signaling pathway
0.42	GO:0030178	negative regulation of Wnt signaling pathway
0.42	GO:1905515	non-motile cilium assembly

0.68	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0045296	cadherin binding
0.38	GO:0050321	tau-protein kinase activity
0.35	GO:0042277	peptide binding
0.32	GO:0003723	RNA binding

0.42	GO:0005634	nucleus
0.41	GO:0005876	spindle microtubule
0.40	GO:0048471	perinuclear region of cytoplasm
0.40	GO:0005815	microtubule organizing center
0.39	GO:0005794	Golgi apparatus
0.37	GO:0030529	intracellular ribonucleoprotein complex
0.36	GO:0043005	neuron projection
0.36	GO:0005886	plasma membrane
0.34	GO:0043025	neuronal cell body
0.34	GO:0030427	site of polarized growth

0.68

GO:0004674

tr|T1FPA1|T1FPA1_HELRO
Uncharacterized protein
Search

PRKACB

0.75	cAMP-dependent protein kinase catalytic subunit alpha

0.62	GO:0006468	protein phosphorylation
0.47	GO:1901621	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
0.45	GO:0001843	neural tube closure
0.45	GO:0070613	regulation of protein processing

0.68	GO:0004674	protein serine/threonine kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0031625	ubiquitin protein ligase binding
0.40	GO:0060089	molecular transducer activity
0.39	GO:0000287	magnesium ion binding

0.46	GO:0045171	intercellular bridge
0.45	GO:0097546	ciliary base
0.43	GO:0005813	centrosome
0.41	GO:0005829	cytosol

0.68

GO:0004674

tr|T1FPA2|T1FPA2_HELRO
Uncharacterized protein
Search

ALDH2

0.37	Mitochondrial aldehyde dehydrogenase 2

0.53	GO:0055114	oxidation-reduction process
0.40	GO:0006068	ethanol catabolic process
0.39	GO:2001038	regulation of cellular response to drug
0.35	GO:0006470	protein dephosphorylation
0.34	GO:0006081	cellular aldehyde metabolic process
0.34	GO:0006468	protein phosphorylation
0.33	GO:0006508	proteolysis
0.33	GO:0005975	carbohydrate metabolic process
0.33	GO:0006091	generation of precursor metabolites and energy

0.69	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.36	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.36	GO:0050662	coenzyme binding
0.35	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors
0.35	GO:1901265	nucleoside phosphate binding
0.34	GO:0036094	small molecule binding
0.34	GO:0004462	lactoylglutathione lyase activity
0.34	GO:0004672	protein kinase activity
0.33	GO:0004222	metalloendopeptidase activity
0.33	GO:0043168	anion binding

0.40	GO:0005739	mitochondrion
0.36	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part
0.34	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.69	EC:1.2.1	GO:0016620
0.34	KEGG:R02530	GO:0004462

tr|T1FPA3|T1FPA3_HELRO
Uncharacterized protein
Search

HM13

0.87	Histocompatibility minor 13

0.61	GO:0006508	proteolysis
0.51	GO:1903513	endoplasmic reticulum to cytosol transport
0.51	GO:0032527	protein exit from endoplasmic reticulum
0.48	GO:0034976	response to endoplasmic reticulum stress
0.48	GO:0010243	response to organonitrogen compound
0.45	GO:0044257	cellular protein catabolic process
0.42	GO:0043523	regulation of neuron apoptotic process
0.34	GO:0051289	protein homotetramerization

0.70	GO:0070001	aspartic-type peptidase activity
0.65	GO:0004175	endopeptidase activity
0.48	GO:0031625	ubiquitin protein ligase binding
0.47	GO:0042803	protein homodimerization activity

0.55	GO:0071458	integral component of cytoplasmic side of endoplasmic reticulum membrane
0.54	GO:0071556	integral component of lumenal side of endoplasmic reticulum membrane
0.51	GO:0036513	Derlin-1 retrotranslocation complex
0.49	GO:0005791	rough endoplasmic reticulum
0.45	GO:0005765	lysosomal membrane
0.44	GO:0030660	Golgi-associated vesicle membrane
0.37	GO:0009986	cell surface
0.33	GO:0005886	plasma membrane

tr|T1FPA4|T1FPA4_HELRO
Uncharacterized protein
Search

PIK3R4

0.49	Phosphoinositide-3-kinase regulatory subunit 4

0.62	GO:0006468	protein phosphorylation
0.56	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity
0.53	GO:0042149	cellular response to glucose starvation
0.52	GO:0032801	receptor catabolic process
0.51	GO:0032465	regulation of cytokinesis
0.47	GO:0030242	autophagy of peroxisome
0.47	GO:0006623	protein targeting to vacuole
0.47	GO:0045324	late endosome to vacuole transport
0.46	GO:0016236	macroautophagy
0.35	GO:0034162	toll-like receptor 9 signaling pathway

0.62	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0016303	1-phosphatidylinositol-3-kinase activity
0.34	GO:0005515	protein binding

0.55	GO:0035032	phosphatidylinositol 3-kinase complex, class III
0.54	GO:0005770	late endosome
0.52	GO:0005930	axoneme
0.49	GO:0071561	nucleus-vacuole junction
0.48	GO:0015630	microtubule cytoskeleton
0.45	GO:0005643	nuclear pore
0.39	GO:0005776	autophagosome
0.35	GO:0030670	phagocytic vesicle membrane
0.33	GO:0005829	cytosol

0.35	EC:2.7.1.137	GO:0016303
0.35	KEGG:R03362	GO:0016303

tr|T1FPA5|T1FPA5_HELRO
Uncharacterized protein
Search

DECR1

0.52	2,4-dienoyl-CoA reductase, mitochondrial

0.80	GO:0051289	protein homotetramerization
0.73	GO:0006635	fatty acid beta-oxidation

0.83	GO:0008670	2,4-dienoyl-CoA reductase (NADPH) activity
0.75	GO:0070402	NADPH binding
0.37	GO:0016651	oxidoreductase activity, acting on NAD(P)H

0.66	GO:0005654	nucleoplasm
0.65	GO:0005829	cytosol
0.58	GO:0005739	mitochondrion
0.43	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.83

EC:1.3.1.34

GO:0008670

tr|T1FPA6|T1FPA6_HELRO
Uncharacterized protein
Search

DDB1

0.87	Damage specific DNA binding protein 1

0.65	GO:0006281	DNA repair
0.57	GO:0046726	positive regulation by virus of viral protein levels in host cell
0.56	GO:1902188	positive regulation of viral release from host cell
0.55	GO:0035518	histone H2A monoubiquitination
0.55	GO:0045070	positive regulation of viral genome replication
0.54	GO:0051702	interaction with symbiont
0.53	GO:0034644	cellular response to UV
0.53	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.52	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.51	GO:0045732	positive regulation of protein catabolic process

0.57	GO:0071987	WD40-repeat domain binding
0.55	GO:0097602	cullin family protein binding
0.51	GO:0030674	protein binding, bridging
0.51	GO:0003676	nucleic acid binding
0.49	GO:0032403	protein complex binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005634	nucleus
0.57	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex
0.55	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex
0.46	GO:0043233	organelle lumen
0.43	GO:0043234	protein complex
0.42	GO:0044446	intracellular organelle part
0.39	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.34	GO:0005694	chromosome

tr|T1FPA7|T1FPA7_HELRO
Uncharacterized protein
Search

NMD3

0.69	60S ribosomal export protein NMD3

0.65	GO:0015031	protein transport
0.45	GO:0033750	ribosome localization
0.45	GO:0071166	ribonucleoprotein complex localization
0.45	GO:0051169	nuclear transport
0.44	GO:0051656	establishment of organelle localization
0.43	GO:0051236	establishment of RNA localization
0.43	GO:0050657	nucleic acid transport
0.41	GO:0034613	cellular protein localization
0.41	GO:0042254	ribosome biogenesis
0.40	GO:1904751	positive regulation of protein localization to nucleolus

0.44	GO:0043023	ribosomal large subunit binding
0.38	GO:0030674	protein binding, bridging
0.34	GO:0003723	RNA binding
0.32	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.32	GO:0016787	hydrolase activity

0.61	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.45	GO:0031974	membrane-enclosed lumen
0.42	GO:0043232	intracellular non-membrane-bounded organelle
0.41	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.32

GO:0016773

tr|T1FPA8|T1FPA8_HELRO
Uncharacterized protein
Search

PIGU

0.84	Phosphatidylinositol glycan anchor biosynthesis class U

0.83	GO:0016255	attachment of GPI anchor to protein
0.52	GO:0046425	regulation of JAK-STAT cascade
0.44	GO:0050976	detection of mechanical stimulus involved in sensory perception of touch
0.44	GO:0034394	protein localization to cell surface
0.34	GO:0042554	superoxide anion generation
0.33	GO:0051301	cell division
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:0055114	oxidation-reduction process
0.32	GO:0007165	signal transduction

0.56	GO:0003923	GPI-anchor transamidase activity
0.55	GO:0034235	GPI anchor binding
0.34	GO:0016175	superoxide-generating NADPH oxidase activity
0.34	GO:0003713	transcription coactivator activity
0.32	GO:0099600	transmembrane receptor activity
0.32	GO:0038023	signaling receptor activity

0.81	GO:0042765	GPI-anchor transamidase complex
0.41	GO:0005886	plasma membrane
0.32	GO:0005634	nucleus

0.56

GO:0003923

tr|T1FPA9|T1FPA9_HELRO
6-phosphogluconate dehydrogenase, decarboxylating
Search

0.55	6-phosphogluconate dehydrogenase, decarboxylating

0.80	GO:0019521	D-gluconate metabolic process
0.72	GO:0006098	pentose-phosphate shunt
0.52	GO:0055114	oxidation-reduction process
0.46	GO:0061688	glycolytic process via Entner-Doudoroff Pathway
0.44	GO:0046176	aldonic acid catabolic process
0.39	GO:0019322	pentose biosynthetic process
0.34	GO:0006886	intracellular protein transport
0.34	GO:0016192	vesicle-mediated transport
0.34	GO:0009737	response to abscisic acid
0.34	GO:0009414	response to water deprivation

0.75	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity
0.40	GO:0050661	NADP binding

0.35

GO:0030131

clathrin adaptor complex

0.75

EC:1.1.1.44

GO:0004616

tr|T1FPB0|T1FPB0_HELRO
Uncharacterized protein
Search

0.52	5-hydroxytryptamine receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.67	GO:0007210	serotonin receptor signaling pathway
0.53	GO:0019933	cAMP-mediated signaling
0.40	GO:0032355	response to estradiol
0.40	GO:0021766	hippocampus development
0.37	GO:0035587	purinergic receptor signaling pathway
0.36	GO:0055117	regulation of cardiac muscle contraction
0.36	GO:0019229	regulation of vasoconstriction
0.36	GO:0095500	acetylcholine receptor signaling pathway
0.33	GO:0032088	negative regulation of NF-kappaB transcription factor activity

0.72	GO:0008227	G-protein coupled amine receptor activity
0.67	GO:0099589	serotonin receptor activity
0.65	GO:0099528	G-protein coupled neurotransmitter receptor activity
0.47	GO:0051378	serotonin binding
0.39	GO:0004952	dopamine neurotransmitter receptor activity
0.37	GO:0001609	G-protein coupled adenosine receptor activity
0.36	GO:0015464	acetylcholine receptor activity
0.35	GO:0008528	G-protein coupled peptide receptor activity
0.33	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors

0.54	GO:0005887	integral component of plasma membrane
0.40	GO:0043204	perikaryon
0.39	GO:0005791	rough endoplasmic reticulum
0.39	GO:0030425	dendrite
0.37	GO:0005794	Golgi apparatus

0.33

EC:1.3

GO:0016627

tr|T1FPB1|T1FPB1_HELRO
Uncharacterized protein
Search

PICK1

0.91	PRKCA-binding protein isoform A

0.54	GO:0015844	monoamine transport
0.52	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway
0.46	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation
0.41	GO:0097062	dendritic spine maintenance
0.41	GO:0060292	long term synaptic depression
0.41	GO:0002092	positive regulation of receptor internalization
0.40	GO:0051126	negative regulation of actin nucleation
0.40	GO:0042149	cellular response to glucose starvation
0.40	GO:0021782	glial cell development
0.40	GO:0036294	cellular response to decreased oxygen levels

0.77	GO:0019904	protein domain specific binding
0.52	GO:0008022	protein C-terminus binding
0.47	GO:0019899	enzyme binding
0.40	GO:0071933	Arp2/3 complex binding
0.39	GO:0051015	actin filament binding
0.37	GO:0001664	G-protein coupled receptor binding
0.36	GO:0042802	identical protein binding
0.36	GO:0016301	kinase activity
0.35	GO:0035255	ionotropic glutamate receptor binding
0.35	GO:0046872	metal ion binding

0.53	GO:0042734	presynaptic membrane
0.53	GO:0016235	aggresome
0.45	GO:0005829	cytosol
0.43	GO:0005739	mitochondrion
0.40	GO:0014069	postsynaptic density
0.39	GO:0045211	postsynaptic membrane
0.39	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0043005	neuron projection
0.38	GO:0030054	cell junction
0.37	GO:0005856	cytoskeleton

tr|T1FPB2|T1FPB2_HELRO
Uncharacterized protein
Search

KCNF1A

0.46	Potassium voltage-gated channel protein Shab

0.75	GO:0051260	protein homooligomerization
0.75	GO:0034765	regulation of ion transmembrane transport
0.73	GO:0071805	potassium ion transmembrane transport
0.35	GO:0060025	regulation of synaptic activity
0.35	GO:0045938	positive regulation of circadian sleep/wake cycle, sleep
0.35	GO:0008345	larval locomotory behavior
0.35	GO:0001508	action potential
0.34	GO:0008016	regulation of heart contraction
0.34	GO:0007268	chemical synaptic transmission

0.78

GO:0005249

voltage-gated potassium channel activity

0.78

GO:0008076

voltage-gated potassium channel complex

tr|T1FPB3|T1FPB3_HELRO
Uncharacterized protein
Search

0.10	Putative apoptosis stimulating of p53 (Fragment)

0.63	GO:0061098	positive regulation of protein tyrosine kinase activity
0.55	GO:0006915	apoptotic process
0.49	GO:0043066	negative regulation of apoptotic process
0.44	GO:0006351	transcription, DNA-templated
0.39	GO:0007165	signal transduction

0.64	GO:0030296	protein tyrosine kinase activator activity
0.52	GO:0002039	p53 binding
0.51	GO:0008134	transcription factor binding
0.39	GO:0102568	phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
0.39	GO:0102567	phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
0.39	GO:0004623	phospholipase A2 activity
0.34	GO:0003676	nucleic acid binding

0.59	GO:0005912	adherens junction
0.36	GO:0005737	cytoplasm
0.35	GO:0005634	nucleus
0.35	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016020	membrane

0.39

EC:3.1.1.4

GO:0004623

tr|T1FPB4|T1FPB4_HELRO
Uncharacterized protein
Search

0.65	GO:0015031	protein transport
0.34	GO:0016579	protein deubiquitination
0.34	GO:0006511	ubiquitin-dependent protein catabolic process
0.33	GO:0006895	Golgi to endosome transport

0.35

GO:0004843

thiol-dependent ubiquitin-specific protease activity

0.32

GO:0005829

cytosol

tr|T1FPB5|T1FPB5_HELRO
Uncharacterized protein
Search

0.27	S1 RNA-binding domain-containing protein 1

0.49	GO:0046483	heterocycle metabolic process
0.49	GO:1901360	organic cyclic compound metabolic process
0.49	GO:0006725	cellular aromatic compound metabolic process
0.45	GO:0006807	nitrogen compound metabolic process
0.36	GO:0006974	cellular response to DNA damage stimulus
0.34	GO:0044260	cellular macromolecule metabolic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process
0.32	GO:0044249	cellular biosynthetic process
0.30	GO:0044238	primary metabolic process

0.51	GO:0003676	nucleic acid binding
0.35	GO:0004654	polyribonucleotide nucleotidyltransferase activity

0.35

GO:0005840

ribosome

0.35

EC:2.7.7.8

GO:0004654

tr|T1FPB6|T1FPB6_HELRO
Uncharacterized protein
Search

CFAP52

0.94	LOW QUALITY PROTEIN: cilia- and flagella-associated protein 52

0.41	GO:0016579	protein deubiquitination
0.41	GO:0006511	ubiquitin-dependent protein catabolic process

0.41	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.39	GO:0005515	protein binding

0.72	GO:0031514	motile cilium
0.39	GO:0005737	cytoplasm

0.41

EC:3.4.19.12

GO:0036459

tr|T1FPB7|T1FPB7_HELRO
Palmitoyltransferase
Search

0.39	Palmitoyltransferase

0.53	GO:0018345	protein palmitoylation
0.48	GO:0018231	peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine
0.48	GO:0048733	sebaceous gland development
0.45	GO:0001942	hair follicle development
0.33	GO:0050999	regulation of nitric-oxide synthase activity
0.33	GO:0006897	endocytosis
0.33	GO:1903830	magnesium ion transmembrane transport
0.32	GO:0006508	proteolysis
0.32	GO:0043043	peptide biosynthetic process
0.31	GO:0010467	gene expression

0.80	GO:0019706	protein-cysteine S-palmitoyltransferase activity
0.34	GO:0004792	thiosulfate sulfurtransferase activity
0.33	GO:0005515	protein binding
0.33	GO:0015095	magnesium ion transmembrane transporter activity
0.32	GO:0004177	aminopeptidase activity
0.32	GO:0019843	rRNA binding
0.32	GO:0003735	structural constituent of ribosome
0.32	GO:0008270	zinc ion binding

0.45	GO:0012505	endomembrane system
0.41	GO:0043231	intracellular membrane-bounded organelle
0.40	GO:0044444	cytoplasmic part
0.38	GO:0005886	plasma membrane
0.35	GO:0031984	organelle subcompartment
0.32	GO:0098588	bounding membrane of organelle
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.32	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

0.80	EC:2.3.1.225	GO:0019706
0.34	KEGG:R01931	GO:0004792

tr|T1FPB8|T1FPB8_HELRO
AP complex subunit beta
Search

0.64	AP complex subunit beta

0.69	GO:0006886	intracellular protein transport
0.69	GO:0016192	vesicle-mediated transport
0.41	GO:0007275	multicellular organism development
0.40	GO:0098657	import into cell
0.38	GO:0051668	localization within membrane
0.37	GO:0043112	receptor metabolic process
0.34	GO:0035335	peptidyl-tyrosine dephosphorylation

0.80	GO:0030276	clathrin binding
0.34	GO:0004725	protein tyrosine phosphatase activity

0.78	GO:0030131	clathrin adaptor complex
0.41	GO:0005905	clathrin-coated pit
0.40	GO:0030136	clathrin-coated vesicle
0.39	GO:0030666	endocytic vesicle membrane
0.38	GO:0030120	vesicle coat
0.37	GO:0005802	trans-Golgi network
0.36	GO:0098797	plasma membrane protein complex

0.34

GO:0004725

tr|T1FPB9|T1FPB9_HELRO
Uncharacterized protein
Search

0.10	Sorting nexin 4

0.63	GO:0015031	protein transport
0.55	GO:1903595	positive regulation of histamine secretion by mast cell
0.52	GO:0032456	endocytic recycling
0.45	GO:0016050	vesicle organization
0.42	GO:0006897	endocytosis

0.74	GO:0035091	phosphatidylinositol binding
0.55	GO:1990460	leptin receptor binding
0.54	GO:1990459	transferrin receptor binding
0.53	GO:0005158	insulin receptor binding
0.53	GO:0005154	epidermal growth factor receptor binding

0.52	GO:0031901	early endosome membrane
0.51	GO:0031201	SNARE complex
0.51	GO:0005868	cytoplasmic dynein complex
0.44	GO:0019898	extrinsic component of membrane
0.40	GO:0005886	plasma membrane

tr|T1FPC0|T1FPC0_HELRO
Uncharacterized protein
Search

0.10	Putative small GTPase superfamily, P-loop containing nucleoside triphosphate hydrolase

0.40	GO:0033298	contractile vacuole organization
0.39	GO:0032482	Rab protein signal transduction
0.39	GO:0051641	cellular localization
0.39	GO:0016192	vesicle-mediated transport
0.39	GO:0007231	osmosensory signaling pathway
0.39	GO:0071476	cellular hypotonic response
0.38	GO:1903024	positive regulation of ascospore-type prospore membrane assembly
0.38	GO:1990395	meiotic spindle pole body organization
0.38	GO:0000281	mitotic cytokinesis
0.37	GO:0033036	macromolecule localization

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.39	GO:0032794	GTPase activating protein binding
0.38	GO:0017112	Rab guanyl-nucleotide exchange factor activity
0.34	GO:0005509	calcium ion binding
0.34	GO:0003676	nucleic acid binding
0.33	GO:0004386	helicase activity
0.33	GO:0004252	serine-type endopeptidase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0008144	drug binding

0.40	GO:0031982	vesicle
0.40	GO:0012505	endomembrane system
0.38	GO:0090619	meiotic spindle pole
0.38	GO:0044444	cytoplasmic part
0.37	GO:0005628	prospore membrane
0.36	GO:0098805	whole membrane
0.36	GO:0043231	intracellular membrane-bounded organelle
0.36	GO:0098588	bounding membrane of organelle
0.35	GO:0071944	cell periphery
0.34	GO:0042555	MCM complex

0.33

GO:0004252

tr|T1FPC1|T1FPC1_HELRO
Uncharacterized protein
Search

0.84	GO:0032218	riboflavin transport
0.52	GO:0007605	sensory perception of sound
0.51	GO:0034605	cellular response to heat

0.84	GO:0032217	riboflavin transmembrane transporter activity
0.33	GO:0005515	protein binding

0.67	GO:0005887	integral component of plasma membrane
0.35	GO:0016324	apical plasma membrane

tr|T1FPC2|T1FPC2_HELRO
Uncharacterized protein
Search

CDO1

0.56	Cysteine dioxygenase type I

0.53	GO:0055114	oxidation-reduction process
0.42	GO:0046305	alkanesulfonate biosynthetic process
0.41	GO:0019530	taurine metabolic process
0.39	GO:0019448	L-cysteine catabolic process
0.38	GO:0033762	response to glucagon
0.38	GO:0007595	lactation
0.38	GO:0051591	response to cAMP
0.37	GO:0051384	response to glucocorticoid
0.37	GO:0045471	response to ethanol
0.37	GO:0043200	response to amino acid

0.75	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.63	GO:0005506	iron ion binding

0.45	GO:0005829	cytosol
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.75

EC:1.13.11

GO:0016702

tr|T1FPC3|T1FPC3_HELRO
Glycerol-3-phosphate dehydrogenase [NAD(+)]
Search

0.66	Glycerol-3-phosphate dehydrogenase [NAD(+)]

0.79	GO:0046168	glycerol-3-phosphate catabolic process
0.60	GO:0005975	carbohydrate metabolic process
0.53	GO:0055114	oxidation-reduction process
0.37	GO:0006973	intracellular accumulation of glycerol
0.36	GO:0007629	flight behavior
0.36	GO:0055093	response to hyperoxia
0.35	GO:0006067	ethanol metabolic process
0.35	GO:0006641	triglyceride metabolic process
0.34	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation
0.33	GO:0007018	microtubule-based movement

0.79	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity
0.75	GO:0042803	protein homodimerization activity
0.68	GO:0051287	NAD binding
0.34	GO:0000213	tRNA-intron endonuclease activity
0.34	GO:0004368	glycerol-3-phosphate dehydrogenase activity
0.33	GO:0003777	microtubule motor activity
0.33	GO:0008017	microtubule binding
0.33	GO:0008168	methyltransferase activity
0.32	GO:0003676	nucleic acid binding
0.32	GO:0005524	ATP binding

0.76	GO:0009331	glycerol-3-phosphate dehydrogenase complex
0.36	GO:0031430	M band
0.35	GO:0030018	Z disc
0.30	GO:0031224	intrinsic component of membrane

0.79	EC:1.1.1.8 EC:1.1.1.94	GO:0004367
0.79	KEGG:R00842	GO:0004367

tr|T1FPC5|T1FPC5_HELRO
Uncharacterized protein
Search

CDK9

0.88	Cell division protein kinase 9

0.63	GO:0006468	protein phosphorylation
0.50	GO:1903839	positive regulation of mRNA 3'-UTR binding
0.49	GO:0033129	positive regulation of histone phosphorylation
0.49	GO:2001168	positive regulation of histone H2B ubiquitination
0.48	GO:0045944	positive regulation of transcription by RNA polymerase II
0.48	GO:1900364	negative regulation of mRNA polyadenylation
0.48	GO:0051726	regulation of cell cycle
0.47	GO:0006368	transcription elongation from RNA polymerase II promoter
0.46	GO:0051147	regulation of muscle cell differentiation
0.46	GO:0031297	replication fork processing

0.68	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0097472	cyclin-dependent protein kinase activity
0.49	GO:0097322	7SK snRNA binding
0.48	GO:0001223	transcription coactivator binding
0.47	GO:0044212	transcription regulatory region DNA binding
0.45	GO:0030332	cyclin binding

0.52	GO:0008024	cyclin/CDK positive transcription elongation factor complex
0.47	GO:0016605	PML body
0.45	GO:0036464	cytoplasmic ribonucleoprotein granule
0.43	GO:0005694	chromosome
0.42	GO:0032783	ELL-EAF complex
0.30	GO:0016020	membrane

0.68

GO:0004674

tr|T1FPC6|T1FPC6_HELRO
Uncharacterized protein
Search

GLYCTK

0.49	Glycerate kinase

0.56	GO:0016310	phosphorylation
0.47	GO:0036211	protein modification process
0.44	GO:0044267	cellular protein metabolic process
0.36	GO:0061624	fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate
0.35	GO:0003341	cilium movement
0.34	GO:0006334	nucleosome assembly
0.34	GO:0006352	DNA-templated transcription, initiation
0.33	GO:0051478	mannosylglycerate metabolic process
0.33	GO:0016138	glycoside biosynthetic process
0.33	GO:0006979	response to oxidative stress

0.58	GO:0016301	kinase activity
0.47	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0016618	hydroxypyruvate reductase activity
0.35	GO:0046982	protein heterodimerization activity
0.35	GO:0004842	ubiquitin-protein transferase activity
0.34	GO:0003777	microtubule motor activity
0.33	GO:0050531	mannosyl-3-phosphoglycerate phosphatase activity

0.49	GO:0005794	Golgi apparatus
0.48	GO:0005829	cytosol
0.35	GO:0000786	nucleosome
0.35	GO:0005858	axonemal dynein complex
0.35	GO:0005739	mitochondrion
0.34	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.47	EC:2.7.1	GO:0016773
0.35	KEGG:R03876	GO:0004842

tr|T1FPC7|T1FPC7_HELRO
Uncharacterized protein
Search

tr|T1FPC8|T1FPC8_HELRO
Uncharacterized protein
Search

tr|T1FPC9|T1FPC9_HELRO
Uncharacterized protein
Search

tr|T1FPD0|T1FPD0_HELRO
Uncharacterized protein
Search

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0002040	sprouting angiogenesis
0.53	GO:0060718	chorionic trophoblast cell differentiation
0.53	GO:0070365	hepatocyte differentiation
0.52	GO:0033301	cell cycle comprising mitosis without cytokinesis
0.50	GO:0032466	negative regulation of cytokinesis
0.49	GO:1902680	positive regulation of RNA biosynthetic process

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.49	GO:0003714	transcription corepressor activity
0.48	GO:0001067	regulatory region nucleic acid binding
0.46	GO:0042803	protein homodimerization activity
0.34	GO:0046872	metal ion binding

0.75	GO:0005667	transcription factor complex
0.61	GO:0005634	nucleus
0.45	GO:0005829	cytosol
0.44	GO:0031974	membrane-enclosed lumen
0.41	GO:0043232	intracellular non-membrane-bounded organelle
0.41	GO:0044446	intracellular organelle part

tr|T1FPD1|T1FPD1_HELRO
Uncharacterized protein
Search

tr|T1FPD2|T1FPD2_HELRO
Uncharacterized protein
Search

tr|T1FPD3|T1FPD3_HELRO
Uncharacterized protein
Search

tr|T1FPD4|T1FPD4_HELRO
Uncharacterized protein
Search

0.53	GO:0045995	regulation of embryonic development
0.51	GO:0030334	regulation of cell migration
0.50	GO:0030155	regulation of cell adhesion
0.50	GO:0007155	cell adhesion
0.44	GO:0007411	axon guidance
0.42	GO:0003412	establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis
0.41	GO:0060035	notochord cell development
0.41	GO:0061303	cornea development in camera-type eye
0.41	GO:0007634	optokinetic behavior
0.40	GO:0048854	brain morphogenesis

0.53	GO:0005509	calcium ion binding
0.48	GO:0005102	receptor binding
0.36	GO:0043236	laminin binding
0.35	GO:0005539	glycosaminoglycan binding
0.35	GO:0050839	cell adhesion molecule binding
0.34	GO:0032403	protein complex binding
0.33	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors
0.33	GO:0050660	flavin adenine dinucleotide binding

0.39	GO:0005576	extracellular region
0.35	GO:0042383	sarcolemma
0.34	GO:0044456	synapse part
0.33	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.33

EC:1.3

GO:0016627

tr|T1FPD5|T1FPD5_HELRO
Uncharacterized protein
Search

0.45	GO:0043113	receptor clustering
0.42	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway
0.41	GO:1903274	negative regulation of sodium ion export
0.41	GO:1903407	negative regulation of sodium:potassium-exchanging ATPase activity
0.41	GO:2000539	regulation of protein geranylgeranylation
0.40	GO:0045213	neurotransmitter receptor metabolic process
0.40	GO:1903276	regulation of sodium ion export across plasma membrane
0.40	GO:0086036	regulation of cardiac muscle cell membrane potential
0.40	GO:0045887	positive regulation of synaptic growth at neuromuscular junction
0.39	GO:0043525	positive regulation of neuron apoptotic process

0.70	GO:0005509	calcium ion binding
0.43	GO:0043236	laminin binding
0.40	GO:0035374	chondroitin sulfate binding
0.40	GO:0033691	sialic acid binding
0.39	GO:0030548	acetylcholine receptor regulator activity
0.39	GO:0002162	dystroglycan binding
0.39	GO:0043395	heparan sulfate proteoglycan binding
0.39	GO:0044325	ion channel binding
0.38	GO:0042030	ATPase inhibitor activity

0.40	GO:0005796	Golgi lumen
0.39	GO:0043083	synaptic cleft
0.39	GO:0005605	basal lamina
0.39	GO:0042383	sarcolemma
0.37	GO:0009986	cell surface
0.37	GO:0030054	cell junction
0.37	GO:0005615	extracellular space
0.36	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

tr|T1FPD6|T1FPD6_HELRO
Uncharacterized protein
Search

TRM2A

0.26	S-adenosyl-L-methionine-dependent methyltransferase

0.69	GO:0001510	RNA methylation
0.63	GO:0006396	RNA processing
0.34	GO:0005975	carbohydrate metabolic process

0.69	GO:0008173	RNA methyltransferase activity
0.51	GO:0003723	RNA binding
0.34	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.34	GO:0030246	carbohydrate binding
0.33	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity
0.33	GO:0140101	catalytic activity, acting on a tRNA
0.33	GO:0046872	metal ion binding
0.32	GO:0051539	4 iron, 4 sulfur cluster binding

0.30

GO:0031224

intrinsic component of membrane

0.69

GO:0008173

tr|T1FPD7|T1FPD7_HELRO
Uncharacterized protein
Search

tr|T1FPD8|T1FPD8_HELRO
Uncharacterized protein
Search

0.61	GO:0006508	proteolysis
0.40	GO:0007218	neuropeptide signaling pathway
0.39	GO:0030282	bone mineralization
0.38	GO:0042445	hormone metabolic process
0.38	GO:0051604	protein maturation
0.36	GO:0006518	peptide metabolic process
0.35	GO:0071492	cellular response to UV-A
0.35	GO:0071493	cellular response to UV-B
0.35	GO:0046449	creatinine metabolic process
0.35	GO:0090399	replicative senescence

0.70	GO:0004222	metalloendopeptidase activity
0.33	GO:0008238	exopeptidase activity
0.33	GO:0004735	pyrroline-5-carboxylate reductase activity
0.33	GO:0008270	zinc ion binding
0.32	GO:0016740	transferase activity

0.42	GO:0016529	sarcoplasmic reticulum
0.39	GO:0005615	extracellular space
0.37	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0005794	Golgi apparatus
0.35	GO:0044306	neuron projection terminus
0.35	GO:0005903	brush border
0.35	GO:0008021	synaptic vesicle
0.34	GO:0030425	dendrite
0.34	GO:0030424	axon
0.34	GO:0045121	membrane raft

0.70

GO:0004222

tr|T1FPD9|T1FPD9_HELRO
Uncharacterized protein
Search

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.39	GO:0007163	establishment or maintenance of cell polarity
0.38	GO:0007015	actin filament organization
0.36	GO:0007275	multicellular organism development
0.36	GO:0007186	G-protein coupled receptor signaling pathway
0.35	GO:0007267	cell-cell signaling
0.35	GO:0072137	condensed mesenchymal cell proliferation
0.35	GO:0007166	cell surface receptor signaling pathway
0.34	GO:0006508	proteolysis

0.70	GO:0005509	calcium ion binding
0.36	GO:0004930	G-protein coupled receptor activity
0.34	GO:0008233	peptidase activity

0.56	GO:0005886	plasma membrane
0.41	GO:0005911	cell-cell junction
0.40	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0030175	filopodium
0.39	GO:0030027	lamellipodium
0.36	GO:0005634	nucleus
0.35	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane

0.34

GO:0008233

tr|T1FPE0|T1FPE0_HELRO
Uncharacterized protein
Search

0.30

GO:0044425

membrane part

tr|T1FPE1|T1FPE1_HELRO
Uncharacterized protein
Search

0.48	GO:0006352	DNA-templated transcription, initiation
0.47	GO:0031498	chromatin disassembly
0.47	GO:0032986	protein-DNA complex disassembly
0.46	GO:0006413	translational initiation
0.45	GO:0035023	regulation of Rho protein signal transduction
0.45	GO:0043044	ATP-dependent chromatin remodeling
0.44	GO:0034728	nucleosome organization
0.44	GO:0006030	chitin metabolic process
0.42	GO:0051716	cellular response to stimulus
0.42	GO:0006357	regulation of transcription by RNA polymerase II

0.57	GO:0046982	protein heterodimerization activity
0.47	GO:0003676	nucleic acid binding
0.45	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.43	GO:0008061	chitin binding
0.39	GO:0003700	DNA binding transcription factor activity

0.57	GO:0005634	nucleus
0.54	GO:0005667	transcription factor complex
0.52	GO:0031248	protein acetyltransferase complex
0.51	GO:0000428	DNA-directed RNA polymerase complex
0.50	GO:0031974	membrane-enclosed lumen
0.50	GO:1905368	peptidase complex
0.47	GO:0044446	intracellular organelle part
0.41	GO:0005694	chromosome
0.41	GO:1904949	ATPase complex
0.40	GO:0005576	extracellular region

tr|T1FPE2|T1FPE2_HELRO
Uncharacterized protein
Search

tr|T1FPE3|T1FPE3_HELRO
Uncharacterized protein
Search

0.56	ABC transporter, ATP-binding protein

0.85	GO:0015910	peroxisomal long-chain fatty acid import
0.55	GO:0055085	transmembrane transport

0.75	GO:0042803	protein homodimerization activity
0.66	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.76	GO:0042579	microbody
0.30	GO:0016020	membrane

tr|T1FPE4|T1FPE4_HELRO
Uncharacterized protein
Search

tr|T1FPE5|T1FPE5_HELRO
Uncharacterized protein
Search

tr|T1FPE6|T1FPE6_HELRO
Uncharacterized protein
Search

tr|T1FPE7|T1FPE7_HELRO
Uncharacterized protein
Search

tr|T1FPE8|T1FPE8_HELRO
Uncharacterized protein
Search

0.51	GO:0006886	intracellular protein transport
0.45	GO:1903506	regulation of nucleic acid-templated transcription
0.45	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.45	GO:0010468	regulation of gene expression
0.42	GO:0032446	protein modification by small protein conjugation
0.39	GO:0006610	ribosomal protein import into nucleus
0.38	GO:0006607	NLS-bearing protein import into nucleus
0.38	GO:0097466	ubiquitin-dependent glycoprotein ERAD pathway
0.38	GO:0018205	peptidyl-lysine modification
0.37	GO:0006491	N-glycan processing

0.57	GO:0008536	Ran GTPase binding
0.47	GO:0003700	DNA binding transcription factor activity
0.40	GO:0031386	protein tag
0.39	GO:0004842	ubiquitin-protein transferase activity
0.38	GO:0008139	nuclear localization sequence binding
0.38	GO:0004386	helicase activity
0.38	GO:0003676	nucleic acid binding
0.37	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.37	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
0.37	GO:0046872	metal ion binding

0.51	GO:0005634	nucleus
0.38	GO:0043233	organelle lumen
0.37	GO:0012505	endomembrane system
0.37	GO:0005777	peroxisome
0.36	GO:0000785	chromatin
0.35	GO:1904949	ATPase complex
0.35	GO:0031967	organelle envelope
0.35	GO:0031090	organelle membrane
0.34	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.37	EC:3.2.1.113	GO:0004571
0.39	KEGG:R03876	GO:0004842

tr|T1FPE9|T1FPE9_HELRO
Uncharacterized protein
Search

0.55	GO:0006999	nuclear pore organization
0.53	GO:0046931	pore complex assembly
0.46	GO:0043623	cellular protein complex assembly
0.37	GO:0007077	mitotic nuclear envelope disassembly
0.36	GO:1900034	regulation of cellular response to heat
0.36	GO:0071431	tRNA-containing ribonucleoprotein complex export from nucleus
0.36	GO:0006110	regulation of glycolytic process
0.36	GO:0051031	tRNA transport
0.36	GO:0060964	regulation of gene silencing by miRNA
0.36	GO:0097064	ncRNA export from nucleus

0.52	GO:0017056	structural constituent of nuclear pore
0.35	GO:0015288	porin activity
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0019001	guanyl nucleotide binding
0.34	GO:0005515	protein binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.78	GO:0005643	nuclear pore
0.50	GO:0034399	nuclear periphery
0.49	GO:0031965	nuclear membrane
0.35	GO:0046930	pore complex
0.34	GO:0043657	host cell

tr|T1FPF0|T1FPF0_HELRO
Uncharacterized protein
Search

tr|T1FPF1|T1FPF1_HELRO
Uncharacterized protein
Search

tr|T1FPF2|T1FPF2_HELRO
Uncharacterized protein
Search

tr|T1FPF3|T1FPF3_HELRO
Uncharacterized protein
Search

tr|T1FPF4|T1FPF4_HELRO
Uncharacterized protein
Search

tr|T1FPF5|T1FPF5_HELRO
Uncharacterized protein
Search

tr|T1FPF6|T1FPF6_HELRO
Uncharacterized protein
Search

tr|T1FPF7|T1FPF7_HELRO
Uncharacterized protein
Search

NADK

0.43	NAD kinase a

0.78	GO:0006741	NADP biosynthetic process
0.72	GO:0019674	NAD metabolic process
0.57	GO:0016310	phosphorylation
0.33	GO:0046034	ATP metabolic process

0.76	GO:0003951	NAD+ kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.76	EC:2.7.1.23	GO:0003951
0.76	KEGG:R00104	GO:0003951

tr|T1FPF8|T1FPF8_HELRO
Uncharacterized protein
Search

tr|T1FPF9|T1FPF9_HELRO
Uncharacterized protein
Search

0.61	GO:0030036	actin cytoskeleton organization
0.44	GO:0035147	branch fusion, open tracheal system
0.39	GO:0090140	regulation of mitochondrial fission
0.35	GO:0007165	signal transduction
0.33	GO:0006471	protein ADP-ribosylation
0.33	GO:0035023	regulation of Rho protein signal transduction
0.33	GO:0051260	protein homooligomerization
0.32	GO:0065009	regulation of molecular function

0.74	GO:0003779	actin binding
0.63	GO:0017048	Rho GTPase binding
0.33	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.33	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.33	GO:0008270	zinc ion binding

0.38	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0016235	aggresome
0.32	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

0.33

EC:2.4.2.30

GO:0003950

tr|T1FPG0|T1FPG0_HELRO
Uncharacterized protein
Search

0.54	GO:0007275	multicellular organism development
0.54	GO:0030154	cell differentiation
0.53	GO:0007009	plasma membrane organization
0.52	GO:0007219	Notch signaling pathway
0.50	GO:0009653	anatomical structure morphogenesis
0.45	GO:0050793	regulation of developmental process
0.41	GO:0009888	tissue development
0.41	GO:0097150	neuronal stem cell population maintenance
0.41	GO:0060322	head development
0.40	GO:0030513	positive regulation of BMP signaling pathway

0.70	GO:0005509	calcium ion binding
0.43	GO:0005112	Notch binding
0.42	GO:0004872	receptor activity
0.39	GO:0003682	chromatin binding
0.38	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.38	GO:0004857	enzyme inhibitor activity
0.38	GO:0001047	core promoter binding
0.38	GO:0019899	enzyme binding
0.37	GO:0046982	protein heterodimerization activity
0.36	GO:0045296	cadherin binding

0.54	GO:0005902	microvillus
0.54	GO:0005913	cell-cell adherens junction
0.44	GO:0043234	protein complex
0.42	GO:0005886	plasma membrane
0.41	GO:0045177	apical part of cell
0.39	GO:0043235	receptor complex
0.39	GO:0005576	extracellular region
0.37	GO:0009986	cell surface
0.37	GO:0001917	photoreceptor inner segment
0.36	GO:0031410	cytoplasmic vesicle

tr|T1FPG1|T1FPG1_HELRO
Uncharacterized protein
Search

tr|T1FPG2|T1FPG2_HELRO
Uncharacterized protein
Search

0.41	Mitogen-activated protein kinase kinase kinase kinase

0.60	GO:0006468	protein phosphorylation
0.56	GO:0001748	optic lobe placode development
0.55	GO:0046529	imaginal disc fusion, thorax closure
0.55	GO:0008594	photoreceptor cell morphogenesis
0.54	GO:0016476	regulation of embryonic cell shape
0.53	GO:0007391	dorsal closure
0.53	GO:1902531	regulation of intracellular signal transduction
0.53	GO:0007097	nuclear migration
0.52	GO:0031098	stress-activated protein kinase signaling cascade
0.51	GO:0007411	axon guidance

0.60	GO:0004672	protein kinase activity
0.52	GO:0032559	adenyl ribonucleotide binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0005057	signal transducer activity, downstream of receptor

0.49	GO:0005938	cell cortex
0.41	GO:0070938	contractile ring

tr|T1FPG3|T1FPG3_HELRO
Uncharacterized protein
Search

tr|T1FPG4|T1FPG4_HELRO
Uncharacterized protein
Search

tr|T1FPG5|T1FPG5_HELRO
Uncharacterized protein
Search

tr|T1FPG6|T1FPG6_HELRO
Uncharacterized protein
Search

0.77	GO:0035023	regulation of Rho protein signal transduction
0.66	GO:0065009	regulation of molecular function
0.39	GO:0001886	endothelial cell morphogenesis
0.39	GO:0097178	ruffle assembly
0.34	GO:0016310	phosphorylation

0.78	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.36	GO:0016740	transferase activity

0.30

GO:0031224

intrinsic component of membrane

0.36

GO:0016740

tr|T1FPG7|T1FPG7_HELRO
Uncharacterized protein
Search

0.10	DNA mismatch repair protein Msh6

0.75	GO:0006298	mismatch repair
0.54	GO:0051096	positive regulation of helicase activity
0.53	GO:0016446	somatic hypermutation of immunoglobulin genes
0.53	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage
0.53	GO:0002204	somatic recombination of immunoglobulin genes involved in immune response
0.52	GO:0045910	negative regulation of DNA recombination
0.52	GO:0002312	B cell activation involved in immune response
0.51	GO:0009411	response to UV
0.51	GO:0045830	positive regulation of isotype switching
0.50	GO:0008340	determination of adult lifespan

0.76	GO:0030983	mismatched DNA binding
0.55	GO:0000400	four-way junction DNA binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.55	GO:0032405	MutLalpha complex binding
0.54	GO:0032357	oxidized purine DNA binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0140034	methylation-dependent protein binding
0.50	GO:0042393	histone binding
0.47	GO:0003682	chromatin binding

0.56	GO:0032301	MutSalpha complex
0.46	GO:0005794	Golgi apparatus
0.46	GO:0000790	nuclear chromatin
0.46	GO:0005654	nucleoplasm
0.45	GO:0005829	cytosol

0.44

GO:0016887

tr|T1FPG8|T1FPG8_HELRO
Uncharacterized protein
Search

0.32	S-adenosyl-L-methionine-dependent methyltransferase

0.62	GO:0032259	methylation
0.40	GO:0006400	tRNA modification
0.39	GO:0051017	actin filament bundle assembly
0.35	GO:0044260	cellular macromolecule metabolic process

0.62	GO:0008168	methyltransferase activity
0.39	GO:0140101	catalytic activity, acting on a tRNA
0.38	GO:0030674	protein binding, bridging
0.38	GO:0051015	actin filament binding
0.34	GO:0030976	thiamine pyrophosphate binding
0.33	GO:0000287	magnesium ion binding
0.33	GO:0005509	calcium ion binding
0.33	GO:0016829	lyase activity

0.39	GO:0032432	actin filament bundle
0.39	GO:0005884	actin filament
0.39	GO:0030479	actin cortical patch
0.30	GO:0016020	membrane

0.62

GO:0008168

tr|T1FPG9|T1FPG9_HELRO
Uncharacterized protein
Search

0.37	GO:0006796	phosphate-containing compound metabolic process
0.36	GO:0036211	protein modification process
0.35	GO:0044267	cellular protein metabolic process
0.33	GO:0006799	polyphosphate biosynthetic process
0.33	GO:0006266	DNA ligation
0.32	GO:0006310	DNA recombination
0.32	GO:0006281	DNA repair

0.61	GO:0008796	bis(5'-nucleosyl)-tetraphosphatase activity
0.37	GO:0016301	kinase activity
0.36	GO:0140096	catalytic activity, acting on a protein
0.35	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.35	GO:0016791	phosphatase activity
0.34	GO:0016151	nickel cation binding
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0019001	guanyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.33	GO:0009358	polyphosphate kinase complex
0.30	GO:0016020	membrane

0.61

EC:3.6.1

GO:0008796

tr|T1FPH0|T1FPH0_HELRO
Uncharacterized protein
Search

0.47	GO:0008380	RNA splicing
0.46	GO:0007155	cell adhesion

0.42	GO:0003723	RNA binding
0.40	GO:0046872	metal ion binding
0.40	GO:0003677	DNA binding

0.30

GO:0044425

membrane part

tr|T1FPH1|T1FPH1_HELRO
Uncharacterized protein
Search

0.44	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.44	GO:1903506	regulation of nucleic acid-templated transcription
0.43	GO:0010468	regulation of gene expression

0.58	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.47	GO:0008270	zinc ion binding
0.41	GO:0003676	nucleic acid binding

0.52	GO:0005634	nucleus
0.30	GO:0044425	membrane part

tr|T1FPH2|T1FPH2_HELRO
Uncharacterized protein
Search

tr|T1FPH3|T1FPH3_HELRO
Alpha-mannosidase
Search

0.47	Alpha-mannosidase

0.81	GO:0006013	mannose metabolic process
0.44	GO:0006517	protein deglycosylation
0.35	GO:0007611	learning or memory

0.79	GO:0004559	alpha-mannosidase activity
0.70	GO:0030246	carbohydrate binding
0.54	GO:0046872	metal ion binding
0.32	GO:0036094	small molecule binding

0.35	GO:0005576	extracellular region
0.35	GO:0005764	lysosome
0.33	GO:0031982	vesicle
0.30	GO:0031224	intrinsic component of membrane

0.79

EC:3.2.1.24

GO:0004559

tr|T1FPH4|T1FPH4_HELRO
Uncharacterized protein
Search

tr|T1FPH5|T1FPH5_HELRO
Uncharacterized protein
Search

0.48

GO:0006465

signal peptide processing

0.42	GO:0016788	hydrolase activity, acting on ester bonds
0.42	GO:0008233	peptidase activity

0.57	GO:0070062	extracellular exosome
0.49	GO:0005787	signal peptidase complex
0.30	GO:0031224	intrinsic component of membrane

0.42

GO:0016788

tr|T1FPH6|T1FPH6_HELRO
Uncharacterized protein
Search

0.82	Histone-lysine N-methyltransferase eggless

0.78	GO:0034968	histone lysine methylation
0.43	GO:0048132	female germ-line stem cell asymmetric division
0.43	GO:0044026	DNA hypermethylation
0.43	GO:0061647	histone H3-K9 modification
0.43	GO:0090309	positive regulation of methylation-dependent chromatin silencing
0.43	GO:0051038	negative regulation of transcription involved in meiotic cell cycle
0.41	GO:0045814	negative regulation of gene expression, epigenetic
0.34	GO:2001229	negative regulation of response to gamma radiation
0.34	GO:0031507	heterochromatin assembly
0.34	GO:0097549	chromatin organization involved in negative regulation of transcription

0.79	GO:0018024	histone-lysine N-methyltransferase activity
0.63	GO:0008270	zinc ion binding
0.54	GO:0003677	DNA binding
0.34	GO:0004672	protein kinase activity
0.34	GO:0052689	carboxylic ester hydrolase activity
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding

0.64	GO:0005694	chromosome
0.61	GO:0005634	nucleus
0.36	GO:0044446	intracellular organelle part
0.34	GO:0005737	cytoplasm
0.34	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.79	EC:2.1.1.43	GO:0018024
0.34	KEGG:R00630	GO:0052689

tr|T1FPH7|T1FPH7_HELRO
Uncharacterized protein
Search

MYO1D

0.75	unconventional myosin-Id

0.74	GO:0007018	microtubule-based movement
0.49	GO:0010923	negative regulation of phosphatase activity
0.45	GO:0048803	imaginal disc-derived male genitalia morphogenesis
0.45	GO:0071907	determination of digestive tract left/right asymmetry
0.43	GO:0007498	mesoderm development
0.42	GO:0051641	cellular localization
0.39	GO:0071976	cell gliding
0.39	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.39	GO:0098927	vesicle-mediated transport between endosomal compartments
0.38	GO:0072678	T cell migration

0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.74	GO:0003779	actin binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0019904	protein domain specific binding
0.39	GO:0030898	actin-dependent ATPase activity
0.39	GO:0005516	calmodulin binding
0.38	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding

0.77	GO:0016459	myosin complex
0.48	GO:0005903	brush border
0.47	GO:0043209	myelin sheath
0.47	GO:0043025	neuronal cell body
0.47	GO:0030424	axon
0.42	GO:0005938	cell cortex
0.40	GO:0031256	leading edge membrane
0.39	GO:0097440	apical dendrite
0.38	GO:0001891	phagocytic cup
0.38	GO:0016323	basolateral plasma membrane

tr|T1FPH8|T1FPH8_HELRO
Tetraspanin
Search

0.47	Tetraspanin

0.30

GO:0044425

membrane part

tr|T1FPH9|T1FPH9_HELRO
Uncharacterized protein
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tr|T1FPI0|T1FPI0_HELRO
Uncharacterized protein
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tr|T1FPI1|T1FPI1_HELRO
Uncharacterized protein
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tr|T1FPI2|T1FPI2_HELRO
Uncharacterized protein
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CHCHD2

0.91	Coiled-coil-helix-coiled-coil-helix domain containing

0.70	GO:1900037	regulation of cellular response to hypoxia
0.65	GO:0045944	positive regulation of transcription by RNA polymerase II
0.61	GO:0007005	mitochondrion organization
0.45	GO:0015980	energy derivation by oxidation of organic compounds
0.44	GO:0009250	glucan biosynthetic process
0.41	GO:0006468	protein phosphorylation
0.36	GO:0006351	transcription, DNA-templated

0.59	GO:0008134	transcription factor binding
0.57	GO:0043565	sequence-specific DNA binding
0.48	GO:0004689	phosphorylase kinase activity
0.45	GO:0005516	calmodulin binding
0.40	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.38	GO:0032559	adenyl ribonucleotide binding
0.38	GO:0008144	drug binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding

0.67	GO:0005758	mitochondrial intermembrane space
0.57	GO:0005634	nucleus
0.48	GO:0005964	phosphorylase kinase complex
0.30	GO:0031224	intrinsic component of membrane

0.48

EC:2.7.11.19

GO:0004689

tr|T1FPI3|T1FPI3_HELRO
Uncharacterized protein
Search

0.10	RNA polymerase I-specific transcription initiation factor RRN3

0.68	GO:0006413	translational initiation
0.52	GO:0006356	regulation of transcription by RNA polymerase I
0.41	GO:0006360	transcription by RNA polymerase I
0.37	GO:0006352	DNA-templated transcription, initiation
0.35	GO:0006629	lipid metabolic process

0.69	GO:0003743	translation initiation factor activity
0.55	GO:0001181	transcription factor activity, core RNA polymerase I binding
0.54	GO:0001042	RNA polymerase I core binding
0.40	GO:0001082	transcription factor activity, RNA polymerase I transcription factor binding
0.40	GO:0001179	RNA polymerase I transcription factor binding
0.39	GO:0000182	rDNA binding
0.38	GO:0001169	transcription factor activity, RNA polymerase I CORE element sequence-specific binding
0.34	GO:0016787	hydrolase activity

0.42	GO:0005634	nucleus
0.36	GO:0031974	membrane-enclosed lumen
0.35	GO:0043232	intracellular non-membrane-bounded organelle
0.35	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.34

GO:0016787

tr|T1FPI4|T1FPI4_HELRO
Uncharacterized protein
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tr|T1FPI5|T1FPI5_HELRO
Uncharacterized protein
Search

tr|T1FPI6|T1FPI6_HELRO
Uncharacterized protein
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tr|T1FPI7|T1FPI7_HELRO
Uncharacterized protein
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tr|T1FPI8|T1FPI8_HELRO
Uncharacterized protein
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tr|T1FPI9|T1FPI9_HELRO
Uncharacterized protein
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MOCS1

0.49	Molybdenum cofactor biosynthesis protein A

0.71	GO:0006777	Mo-molybdopterin cofactor biosynthetic process
0.40	GO:0032324	molybdopterin cofactor biosynthetic process

0.65	GO:0051539	4 iron, 4 sulfur cluster binding
0.53	GO:0046872	metal ion binding
0.40	GO:0061799	cyclic pyranopterin monophosphate synthase activity
0.40	GO:0061798	GTP 3',8'-cyclase activity
0.36	GO:0032550	purine ribonucleoside binding
0.36	GO:0019001	guanyl nucleotide binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.76	GO:0019008	molybdopterin synthase complex
0.34	GO:0005829	cytosol
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.40

EC:4.6.1.17

GO:0061799

tr|T1FPJ0|T1FPJ0_HELRO
Uncharacterized protein
Search

0.62	GO:0043547	positive regulation of GTPase activity
0.41	GO:0036211	protein modification process
0.40	GO:0044267	cellular protein metabolic process
0.40	GO:0007010	cytoskeleton organization
0.39	GO:0016310	phosphorylation
0.38	GO:0009116	nucleoside metabolic process
0.38	GO:0007165	signal transduction

0.63	GO:0005096	GTPase activator activity
0.46	GO:0046872	metal ion binding
0.42	GO:0140096	catalytic activity, acting on a protein
0.41	GO:0016409	palmitoyltransferase activity
0.40	GO:0031625	ubiquitin protein ligase binding
0.40	GO:0016417	S-acyltransferase activity
0.40	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.39	GO:0016301	kinase activity
0.38	GO:0032559	adenyl ribonucleotide binding
0.38	GO:0008144	drug binding

0.42	GO:0030139	endocytic vesicle
0.40	GO:0000151	ubiquitin ligase complex
0.37	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.41

GO:0016409

tr|T1FPJ1|T1FPJ1_HELRO
Uncharacterized protein
Search

TMEM55A

0.96	Type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase

0.81

GO:0046856

phosphatidylinositol dephosphorylation

0.86

GO:0034597

phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity

0.46	GO:0031902	late endosome membrane
0.46	GO:0005765	lysosomal membrane
0.30	GO:0031224	intrinsic component of membrane

0.86

EC:3.1.3.66

GO:0034597

tr|T1FPJ2|T1FPJ2_HELRO
Uncharacterized protein
Search

tr|T1FPJ3|T1FPJ3_HELRO
Uncharacterized protein
Search

0.84	GO:0035735	intraciliary transport involved in cilium assembly
0.52	GO:0071539	protein localization to centrosome
0.52	GO:0010824	regulation of centrosome duplication
0.50	GO:0090316	positive regulation of intracellular protein transport
0.49	GO:0008284	positive regulation of cell proliferation
0.38	GO:0097503	sialylation
0.37	GO:0043413	macromolecule glycosylation
0.37	GO:0009101	glycoprotein biosynthetic process
0.37	GO:0097711	ciliary basal body-plasma membrane docking
0.36	GO:0007275	multicellular organism development

0.47	GO:0042803	protein homodimerization activity
0.47	GO:0032403	protein complex binding
0.38	GO:0008373	sialyltransferase activity
0.35	GO:0004842	ubiquitin-protein transferase activity
0.34	GO:0005102	receptor binding
0.34	GO:0016874	ligase activity
0.34	GO:0016887	ATPase activity
0.33	GO:0046872	metal ion binding
0.33	GO:0030507	spectrin binding
0.33	GO:0005516	calmodulin binding

0.73	GO:0005929	cilium
0.53	GO:0034451	centriolar satellite
0.51	GO:0045171	intercellular bridge
0.47	GO:0120038	plasma membrane bounded cell projection part
0.40	GO:0043231	intracellular membrane-bounded organelle
0.36	GO:0001669	acrosomal vesicle
0.35	GO:0005610	laminin-5 complex
0.34	GO:0005829	cytosol
0.33	GO:0005874	microtubule
0.30	GO:0031224	intrinsic component of membrane

0.38	EC:2.4.99	GO:0008373
0.35	KEGG:R03876	GO:0004842

tr|T1FPJ4|T1FPJ4_HELRO
Uncharacterized protein
Search

tr|T1FPJ5|T1FPJ5_HELRO
Uncharacterized protein
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tr|T1FPJ6|T1FPJ6_HELRO
Uncharacterized protein
Search

tr|T1FPJ7|T1FPJ7_HELRO
Uncharacterized protein
Search

0.73	Group XV phospholipase A2

0.62	GO:0006629	lipid metabolic process
0.35	GO:0034968	histone lysine methylation
0.33	GO:0006468	protein phosphorylation
0.33	GO:0048149	behavioral response to ethanol
0.33	GO:0007616	long-term memory
0.33	GO:0007165	signal transduction
0.33	GO:0006508	proteolysis
0.33	GO:0050482	arachidonic acid secretion
0.32	GO:0045859	regulation of protein kinase activity
0.32	GO:0000272	polysaccharide catabolic process

0.73	GO:0008374	O-acyltransferase activity
0.35	GO:0018024	histone-lysine N-methyltransferase activity
0.34	GO:0003682	chromatin binding
0.34	GO:0004672	protein kinase activity
0.33	GO:0046872	metal ion binding
0.33	GO:0008195	phosphatidate phosphatase activity
0.33	GO:0008233	peptidase activity
0.33	GO:0003677	DNA binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0004623	phospholipase A2 activity

0.35	GO:0070701	mucus layer
0.33	GO:0005634	nucleus
0.33	GO:0098549	somatic ring canal
0.33	GO:0035324	female germline ring canal
0.33	GO:0031588	nucleotide-activated protein kinase complex
0.32	GO:0031012	extracellular matrix
0.32	GO:0031410	cytoplasmic vesicle
0.30	GO:0031224	intrinsic component of membrane

0.73

GO:0008374

tr|T1FPJ8|T1FPJ8_HELRO
Uncharacterized protein
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tr|T1FPJ9|T1FPJ9_HELRO
Uncharacterized protein
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tr|T1FPK0|T1FPK0_HELRO
Uncharacterized protein
Search

0.46	GO:0044267	cellular protein metabolic process
0.44	GO:0043043	peptide biosynthetic process
0.44	GO:0043632	modification-dependent macromolecule catabolic process
0.44	GO:0030163	protein catabolic process
0.42	GO:0010467	gene expression
0.42	GO:0009059	macromolecule biosynthetic process
0.40	GO:0006508	proteolysis
0.40	GO:0035483	gastric emptying
0.39	GO:0032790	ribosome disassembly
0.39	GO:0032259	methylation

0.46	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.40	GO:0008168	methyltransferase activity
0.39	GO:0003700	DNA binding transcription factor activity
0.38	GO:0043023	ribosomal large subunit binding
0.36	GO:0046872	metal ion binding
0.35	GO:0003676	nucleic acid binding

0.51	GO:0005634	nucleus
0.39	GO:0020011	apicoplast
0.38	GO:1905369	endopeptidase complex
0.35	GO:0043234	protein complex
0.35	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.46

EC:3.4.19.12

GO:0036459

tr|T1FPK1|T1FPK1_HELRO
Uncharacterized protein
Search

0.38	GO:0045892	negative regulation of transcription, DNA-templated
0.35	GO:0055114	oxidation-reduction process

0.65	GO:0005201	extracellular matrix structural constituent
0.43	GO:0042302	structural constituent of cuticle
0.40	GO:0003714	transcription corepressor activity
0.37	GO:0050660	flavin adenine dinucleotide binding
0.37	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors

0.65	GO:0005581	collagen trimer
0.40	GO:0005604	basement membrane
0.30	GO:0044425	membrane part

0.37

EC:1.1

GO:0016614

tr|T1FPK2|T1FPK2_HELRO
Uncharacterized protein
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tr|T1FPK3|T1FPK3_HELRO
Uncharacterized protein
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tr|T1FPK4|T1FPK4_HELRO
Uncharacterized protein
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tr|T1FPK5|T1FPK5_HELRO
Uncharacterized protein
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tr|T1FPK6|T1FPK6_HELRO
Uncharacterized protein
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tr|T1FPK7|T1FPK7_HELRO
Uncharacterized protein
Search

0.51	GO:0048015	phosphatidylinositol-mediated signaling
0.49	GO:0046854	phosphatidylinositol phosphorylation

0.36	GO:0005622	intracellular
0.30	GO:0044425	membrane part

tr|T1FPK8|T1FPK8_HELRO
Transporter
Search

0.47	Sodium- and chloride-dependent glycine transporter 1

0.76	GO:0006836	neurotransmitter transport
0.59	GO:0003333	amino acid transmembrane transport
0.49	GO:0015807	L-amino acid transport
0.48	GO:0015804	neutral amino acid transport
0.46	GO:0060012	synaptic transmission, glycinergic
0.46	GO:0015893	drug transport
0.45	GO:0001505	regulation of neurotransmitter levels
0.44	GO:0099643	signal release from synapse
0.44	GO:0043090	amino acid import
0.44	GO:0099531	presynaptic process involved in chemical synaptic transmission

0.79	GO:0005328	neurotransmitter:sodium symporter activity
0.61	GO:0005283	sodium:amino acid symporter activity
0.53	GO:0015187	glycine transmembrane transporter activity
0.42	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity
0.42	GO:0015296	anion:cation symporter activity
0.33	GO:0005515	protein binding
0.32	GO:0005272	sodium channel activity

0.53	GO:0005887	integral component of plasma membrane
0.45	GO:0044456	synapse part
0.42	GO:0097458	neuron part

tr|T1FPK9|T1FPK9_HELRO
Uncharacterized protein
Search

tr|T1FPL0|T1FPL0_HELRO
Uncharacterized protein
Search

0.61	GO:0014002	astrocyte development
0.59	GO:0001654	eye development
0.58	GO:0000904	cell morphogenesis involved in differentiation
0.58	GO:0007601	visual perception
0.44	GO:0007634	optokinetic behavior
0.44	GO:0048570	notochord morphogenesis
0.44	GO:0050962	detection of light stimulus involved in sensory perception
0.43	GO:0048854	brain morphogenesis
0.43	GO:0061053	somite development
0.43	GO:0007519	skeletal muscle tissue development

0.41	GO:0016849	phosphorus-oxygen lyase activity
0.40	GO:0005198	structural molecule activity
0.36	GO:1901265	nucleoside phosphate binding
0.35	GO:0036094	small molecule binding

0.60	GO:0005604	basement membrane
0.46	GO:0005882	intermediate filament
0.30	GO:0016020	membrane

0.41

EC:4.6

GO:0016849

tr|T1FPL1|T1FPL1_HELRO
Uncharacterized protein
Search

CPQ

0.87	Plasma glutamate carboxypeptidase

0.58	GO:0006508	proteolysis
0.52	GO:0006590	thyroid hormone generation
0.51	GO:0043171	peptide catabolic process
0.43	GO:0042246	tissue regeneration

0.65	GO:0008238	exopeptidase activity
0.50	GO:0042803	protein homodimerization activity
0.47	GO:0008237	metallopeptidase activity
0.35	GO:0046872	metal ion binding
0.33	GO:0003723	RNA binding

0.50	GO:0005615	extracellular space
0.49	GO:0005794	Golgi apparatus
0.42	GO:0005764	lysosome
0.40	GO:0005783	endoplasmic reticulum
0.37	GO:1903561	extracellular vesicle
0.30	GO:0031224	intrinsic component of membrane

tr|T1FPL2|T1FPL2_HELRO
Uncharacterized protein
Search

tr|T1FPL3|T1FPL3_HELRO
Uncharacterized protein
Search

0.56	GO:0008203	cholesterol metabolic process
0.52	GO:0006364	rRNA processing
0.51	GO:0016042	lipid catabolic process
0.48	GO:0032392	DNA geometric change
0.47	GO:0042274	ribosomal small subunit biogenesis
0.47	GO:0006260	DNA replication
0.46	GO:0010469	regulation of receptor activity
0.46	GO:0006281	DNA repair

0.53	GO:0043140	ATP-dependent 3'-5' DNA helicase activity
0.52	GO:0016298	lipase activity
0.47	GO:0008083	growth factor activity
0.41	GO:0032559	adenyl ribonucleotide binding
0.41	GO:0008144	drug binding
0.41	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0003676	nucleic acid binding

0.55	GO:0005730	nucleolus
0.49	GO:0030686	90S preribosome
0.48	GO:0032040	small-subunit processome
0.41	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.52

EC:3.1.1

GO:0016298

tr|T1FPL4|T1FPL4_HELRO
Uncharacterized protein
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tr|T1FPL5|T1FPL5_HELRO
Uncharacterized protein
Search

tr|T1FPL6|T1FPL6_HELRO
Uncharacterized protein
Search

0.52	GO:0036211	protein modification process
0.49	GO:0044267	cellular protein metabolic process
0.47	GO:0016310	phosphorylation
0.46	GO:0016569	covalent chromatin modification
0.44	GO:0045292	mRNA cis splicing, via spliceosome
0.44	GO:0007018	microtubule-based movement
0.43	GO:0048015	phosphatidylinositol-mediated signaling
0.43	GO:0051028	mRNA transport
0.41	GO:0046488	phosphatidylinositol metabolic process
0.41	GO:0030258	lipid modification

0.50	GO:0004672	protein kinase activity
0.47	GO:0030554	adenyl nucleotide binding
0.46	GO:0032555	purine ribonucleotide binding
0.46	GO:0008144	drug binding
0.46	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0004402	histone acetyltransferase activity
0.44	GO:0000339	RNA cap binding
0.44	GO:0003777	microtubule motor activity
0.44	GO:0008017	microtubule binding
0.44	GO:0003779	actin binding

0.48	GO:0072487	MSL complex
0.45	GO:0005846	nuclear cap binding complex
0.45	GO:0016459	myosin complex
0.44	GO:1990429	peroxisomal importomer complex
0.30	GO:0016020	membrane

0.46	EC:2.3.1.48	GO:0004402
0.41	KEGG:R03361	GO:0004430

tr|T1FPL7|T1FPL7_HELRO
Uncharacterized protein
Search

0.51	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.48	GO:0000209	protein polyubiquitination
0.37	GO:0006915	apoptotic process
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:0010468	regulation of gene expression

0.63	GO:0008270	zinc ion binding
0.49	GO:0043621	protein self-association
0.47	GO:0016874	ligase activity
0.46	GO:0061630	ubiquitin protein ligase activity
0.39	GO:0005507	copper ion binding
0.37	GO:0003700	DNA binding transcription factor activity
0.35	GO:0003677	DNA binding

0.37	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.47

GO:0016874

tr|T1FPL8|T1FPL8_HELRO
Uncharacterized protein
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tr|T1FPL9|T1FPL9_HELRO
Uncharacterized protein
Search

TBC1D10A

0.70	Gh regulated tbc protein-1

0.71	GO:0051345	positive regulation of hydrolase activity
0.69	GO:0042147	retrograde transport, endosome to Golgi
0.69	GO:0043087	regulation of GTPase activity
0.69	GO:0031338	regulation of vesicle fusion
0.58	GO:0006886	intracellular protein transport
0.55	GO:0035149	lumen formation, open tracheal system
0.49	GO:0031638	zymogen activation
0.48	GO:2000116	regulation of cysteine-type endopeptidase activity
0.47	GO:0045862	positive regulation of proteolysis
0.44	GO:1902017	regulation of cilium assembly

0.70	GO:0005096	GTPase activator activity
0.66	GO:0017137	Rab GTPase binding
0.49	GO:0030165	PDZ domain binding
0.48	GO:0045296	cadherin binding
0.37	GO:0005085	guanyl-nucleotide exchange factor activity
0.34	GO:0003723	RNA binding

0.60	GO:0005829	cytosol
0.56	GO:0012505	endomembrane system
0.53	GO:0098858	actin-based cell projection
0.50	GO:0005886	plasma membrane
0.38	GO:0070062	extracellular exosome

tr|T1FPM0|T1FPM0_HELRO
Uncharacterized protein
Search

0.61	FGFR1 oncogene partner 2

tr|T1FPM1|T1FPM1_HELRO
Uncharacterized protein
Search

tr|T1FPM2|T1FPM2_HELRO
Uncharacterized protein
Search

0.66	GO:0046854	phosphatidylinositol phosphorylation
0.41	GO:0034968	histone lysine methylation
0.37	GO:0006468	protein phosphorylation
0.36	GO:0000959	mitochondrial RNA metabolic process
0.35	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.35	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.35	GO:0016567	protein ubiquitination
0.34	GO:0051301	cell division

0.73	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity
0.50	GO:0032559	adenyl ribonucleotide binding
0.50	GO:0008144	drug binding
0.50	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0018024	histone-lysine N-methyltransferase activity
0.37	GO:0004672	protein kinase activity
0.36	GO:0050032	L-rhamnonate dehydratase activity
0.35	GO:0004519	endonuclease activity
0.35	GO:0004040	amidase activity
0.35	GO:0004842	ubiquitin-protein transferase activity

0.34	GO:0031226	intrinsic component of plasma membrane
0.34	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

0.73	EC:2.7.1.68	GO:0016308
0.73	KEGG:R03469	GO:0016308

tr|T1FPM3|T1FPM3_HELRO
Uncharacterized protein
Search

tr|T1FPM4|T1FPM4_HELRO
Uncharacterized protein
Search

tr|T1FPM5|T1FPM5_HELRO
Uncharacterized protein
Search

0.51	GO:0045944	positive regulation of transcription by RNA polymerase II
0.46	GO:0033566	gamma-tubulin complex localization
0.45	GO:0035335	peptidyl-tyrosine dephosphorylation
0.45	GO:0007512	adult heart development
0.45	GO:1904707	positive regulation of vascular smooth muscle cell proliferation
0.45	GO:0001958	endochondral ossification
0.44	GO:0006351	transcription, DNA-templated
0.44	GO:0035914	skeletal muscle cell differentiation
0.44	GO:0002062	chondrocyte differentiation
0.44	GO:0001649	osteoblast differentiation

0.52	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.48	GO:0046983	protein dimerization activity
0.47	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.45	GO:0004725	protein tyrosine phosphatase activity
0.44	GO:0033613	activating transcription factor binding
0.44	GO:0042826	histone deacetylase binding
0.43	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.43	GO:0000987	proximal promoter sequence-specific DNA binding
0.42	GO:0004842	ubiquitin-protein transferase activity
0.42	GO:0042802	identical protein binding

0.51	GO:0005634	nucleus
0.46	GO:0008274	gamma-tubulin ring complex
0.45	GO:0043233	organelle lumen
0.44	GO:0031461	cullin-RING ubiquitin ligase complex
0.41	GO:0012505	endomembrane system
0.39	GO:0030134	COPII-coated ER to Golgi transport vesicle
0.39	GO:0030120	vesicle coat
0.39	GO:0030660	Golgi-associated vesicle membrane
0.39	GO:0035068	micro-ribonucleoprotein complex
0.38	GO:0000932	P-body

0.47	EC:3.1.3	GO:0008138
0.42	KEGG:R03876	GO:0004842

tr|T1FPM6|T1FPM6_HELRO
Uncharacterized protein
Search

0.52	GO:0005975	carbohydrate metabolic process
0.45	GO:0048149	behavioral response to ethanol
0.44	GO:0007616	long-term memory
0.44	GO:0009057	macromolecule catabolic process
0.43	GO:0006508	proteolysis
0.42	GO:0042127	regulation of cell proliferation
0.39	GO:0071554	cell wall organization or biogenesis
0.38	GO:0035335	peptidyl-tyrosine dephosphorylation
0.38	GO:0044248	cellular catabolic process
0.38	GO:0007229	integrin-mediated signaling pathway

0.59	GO:0030248	cellulose binding
0.51	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.44	GO:0140096	catalytic activity, acting on a protein
0.41	GO:0005509	calcium ion binding
0.40	GO:0008270	zinc ion binding
0.37	GO:0016791	phosphatase activity
0.36	GO:0050660	flavin adenine dinucleotide binding
0.36	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors
0.36	GO:0017171	serine hydrolase activity
0.35	GO:0016773	phosphotransferase activity, alcohol group as acceptor

0.53	GO:0005576	extracellular region
0.41	GO:0031410	cytoplasmic vesicle
0.30	GO:0016020	membrane

0.51

GO:0004553

tr|T1FPM7|T1FPM7_HELRO
Uncharacterized protein
Search

0.54	GO:1904643	response to curcumin
0.53	GO:1903778	protein localization to vacuolar membrane
0.53	GO:0010513	positive regulation of phosphatidylinositol biosynthetic process
0.52	GO:0031152	aggregation involved in sorocarp development
0.49	GO:0051409	response to nitrosative stress
0.49	GO:0006972	hyperosmotic response
0.49	GO:0019933	cAMP-mediated signaling
0.48	GO:0036211	protein modification process
0.48	GO:0033674	positive regulation of kinase activity
0.47	GO:0032259	methylation

0.48	GO:0004712	protein serine/threonine/tyrosine kinase activity
0.48	GO:0018024	histone-lysine N-methyltransferase activity
0.47	GO:0003682	chromatin binding
0.44	GO:0004674	protein serine/threonine kinase activity
0.42	GO:0030554	adenyl nucleotide binding
0.42	GO:0032555	purine ribonucleotide binding
0.42	GO:0008144	drug binding
0.42	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0046872	metal ion binding
0.42	GO:0003700	DNA binding transcription factor activity

0.51	GO:0070772	PAS complex
0.49	GO:0000329	fungal-type vacuole membrane
0.44	GO:0005829	cytosol
0.41	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.48

EC:2.7.12.1

GO:0004712

tr|T1FPM8|T1FPM8_HELRO
Uncharacterized protein
Search

tr|T1FPM9|T1FPM9_HELRO
Uncharacterized protein
Search

tr|T1FPN0|T1FPN0_HELRO
Uncharacterized protein
Search

tr|T1FPN1|T1FPN1_HELRO
Uncharacterized protein
Search

0.48	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.48	GO:0000209	protein polyubiquitination
0.46	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.37	GO:0048364	root development
0.35	GO:0051301	cell division

0.60	GO:0016874	ligase activity
0.46	GO:0061630	ubiquitin protein ligase activity
0.37	GO:0008270	zinc ion binding

0.39

GO:0005829

cytosol

0.60

GO:0016874

tr|T1FPN2|T1FPN2_HELRO
Uncharacterized protein
Search

0.52	GO:0006275	regulation of DNA replication
0.51	GO:0045893	positive regulation of transcription, DNA-templated
0.47	GO:0006260	DNA replication
0.41	GO:0043547	positive regulation of GTPase activity
0.41	GO:0009734	auxin-activated signaling pathway
0.41	GO:0051568	histone H3-K4 methylation
0.40	GO:0007162	negative regulation of cell adhesion
0.39	GO:0001932	regulation of protein phosphorylation
0.38	GO:0006351	transcription, DNA-templated
0.38	GO:0009908	flower development

0.53	GO:0003688	DNA replication origin binding
0.44	GO:0003713	transcription coactivator activity
0.42	GO:0005515	protein binding
0.41	GO:0030234	enzyme regulator activity
0.41	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.40	GO:0046872	metal ion binding
0.40	GO:0003682	chromatin binding
0.38	GO:0005545	1-phosphatidylinositol binding
0.37	GO:0044877	macromolecular complex binding
0.37	GO:0035591	signaling adaptor activity

0.47	GO:0042025	host cell nucleus
0.46	GO:0005634	nucleus
0.40	GO:1990234	transferase complex
0.40	GO:0070013	intracellular organelle lumen
0.38	GO:0044446	intracellular organelle part
0.37	GO:0030136	clathrin-coated vesicle
0.37	GO:0005667	transcription factor complex
0.35	GO:0005886	plasma membrane
0.35	GO:0012505	endomembrane system
0.35	GO:0099503	secretory vesicle

0.37

GO:0004721

tr|T1FPN3|T1FPN3_HELRO
Uncharacterized protein
Search

0.73	Suppressor of lurcher protein 1

0.49	GO:0001764	neuron migration
0.49	GO:2000312	regulation of kainate selective glutamate receptor activity
0.47	GO:0031175	neuron projection development
0.44	GO:0006898	receptor-mediated endocytosis
0.41	GO:0006508	proteolysis
0.40	GO:0018996	molting cycle, collagen and cuticulin-based cuticle
0.40	GO:0043632	modification-dependent macromolecule catabolic process
0.40	GO:0044257	cellular protein catabolic process
0.40	GO:0048008	platelet-derived growth factor receptor signaling pathway
0.39	GO:0006955	immune response

0.45	GO:0005044	scavenger receptor activity
0.44	GO:0005509	calcium ion binding
0.41	GO:0004471	malate dehydrogenase (decarboxylating) (NAD+) activity
0.40	GO:0005161	platelet-derived growth factor receptor binding
0.40	GO:0001871	pattern binding
0.39	GO:0051287	NAD binding
0.39	GO:0004175	endopeptidase activity
0.38	GO:0022850	serotonin-gated cation-selective channel activity
0.38	GO:0008083	growth factor activity
0.38	GO:0030246	carbohydrate binding

0.42	GO:0005887	integral component of plasma membrane
0.38	GO:0005576	extracellular region
0.37	GO:0005903	brush border
0.37	GO:0016324	apical plasma membrane
0.37	GO:0030139	endocytic vesicle
0.37	GO:0005905	clathrin-coated pit
0.36	GO:0005768	endosome
0.36	GO:0005794	Golgi apparatus
0.36	GO:0005783	endoplasmic reticulum

0.41	EC:1.1.1.38 EC:1.1.1.39	GO:0004471
0.41	KEGG:R00214	GO:0004471

tr|T1FPN4|T1FPN4_HELRO
Uncharacterized protein
Search

tr|T1FPN5|T1FPN5_HELRO
Uncharacterized protein
Search

tr|T1FPN6|T1FPN6_HELRO
Uncharacterized protein
Search

0.53	GO:0006914	autophagy
0.39	GO:0036211	protein modification process
0.39	GO:0065007	biological regulation
0.39	GO:0016070	RNA metabolic process
0.39	GO:0030010	establishment of cell polarity
0.38	GO:0043413	macromolecule glycosylation
0.38	GO:0009101	glycoprotein biosynthetic process
0.38	GO:0044267	cellular protein metabolic process
0.38	GO:0051649	establishment of localization in cell
0.38	GO:0016043	cellular component organization

0.42	GO:0046872	metal ion binding
0.40	GO:0043531	ADP binding
0.39	GO:0031386	protein tag
0.38	GO:0003676	nucleic acid binding
0.38	GO:0003724	RNA helicase activity
0.37	GO:0140110	transcription regulator activity
0.37	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed
0.37	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.37	GO:0005515	protein binding
0.37	GO:0016757	transferase activity, transferring glycosyl groups

0.46	GO:0043231	intracellular membrane-bounded organelle
0.40	GO:0015630	microtubule cytoskeleton
0.39	GO:0044430	cytoskeletal part
0.39	GO:0099512	supramolecular fiber
0.38	GO:0089713	Cbf1-Met4-Met28 complex
0.37	GO:1990234	transferase complex
0.36	GO:0032045	guanyl-nucleotide exchange factor complex
0.36	GO:0070013	intracellular organelle lumen
0.36	GO:0005737	cytoplasm
0.35	GO:1905368	peptidase complex

0.38

GO:0003724

tr|T1FPN7|T1FPN7_HELRO
Uncharacterized protein
Search

0.55	Uridine-cytidine kinase

0.74	GO:0043097	pyrimidine nucleoside salvage
0.74	GO:0032262	pyrimidine nucleotide salvage
0.71	GO:0046035	CMP metabolic process
0.69	GO:0006222	UMP biosynthetic process
0.67	GO:0046036	CTP metabolic process
0.67	GO:0009209	pyrimidine ribonucleoside triphosphate biosynthetic process
0.57	GO:0016310	phosphorylation
0.44	GO:0006206	pyrimidine nucleobase metabolic process
0.34	GO:0048678	response to axon injury
0.34	GO:0007631	feeding behavior

0.78	GO:0019206	nucleoside kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0004639	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
0.34	GO:0005515	protein binding
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0032561	guanyl ribonucleotide binding

0.43	GO:0005829	cytosol
0.32	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.35	EC:6.3.2.6	GO:0004639
0.35	KEGG:R04591	GO:0004639

tr|T1FPN8|T1FPN8_HELRO
Uncharacterized protein
Search

0.44	GO:0007411	axon guidance
0.44	GO:0007160	cell-matrix adhesion
0.44	GO:0050808	synapse organization
0.43	GO:0016477	cell migration
0.37	GO:0010975	regulation of neuron projection development
0.36	GO:0061387	regulation of extent of cell growth
0.36	GO:0010770	positive regulation of cell morphogenesis involved in differentiation
0.36	GO:0045162	clustering of voltage-gated sodium channels
0.36	GO:0030307	positive regulation of cell growth
0.36	GO:0048639	positive regulation of developmental growth

0.43	GO:0019904	protein domain specific binding
0.36	GO:0030506	ankyrin binding
0.36	GO:0033691	sialic acid binding
0.35	GO:0043621	protein self-association
0.35	GO:0005178	integrin binding
0.35	GO:0086080	protein binding involved in heterotypic cell-cell adhesion
0.34	GO:0004896	cytokine receptor activity
0.34	GO:0042802	identical protein binding
0.34	GO:0003714	transcription corepressor activity
0.34	GO:0042393	histone binding

0.44	GO:0030424	axon
0.44	GO:0043025	neuronal cell body
0.43	GO:0009986	cell surface
0.42	GO:0031012	extracellular matrix
0.37	GO:0005886	plasma membrane
0.36	GO:0030426	growth cone
0.35	GO:0045202	synapse
0.35	GO:0044306	neuron projection terminus
0.35	GO:0005925	focal adhesion
0.35	GO:0030425	dendrite

tr|T1FPN9|T1FPN9_HELRO
Uncharacterized protein
Search

tr|T1FPP0|T1FPP0_HELRO
Uncharacterized protein
Search

0.40	GO:0010951	negative regulation of endopeptidase activity
0.39	GO:0030198	extracellular matrix organization
0.38	GO:0071230	cellular response to amino acid stimulus
0.38	GO:0048513	animal organ development
0.38	GO:0009653	anatomical structure morphogenesis
0.38	GO:0061326	renal tubule development
0.37	GO:0072359	circulatory system development
0.37	GO:0070208	protein heterotrimerization
0.36	GO:0009790	embryo development
0.36	GO:0060322	head development

0.62	GO:0005201	extracellular matrix structural constituent
0.41	GO:0004867	serine-type endopeptidase inhibitor activity
0.38	GO:0048407	platelet-derived growth factor binding
0.38	GO:0030246	carbohydrate binding
0.37	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.36	GO:0042302	structural constituent of cuticle
0.36	GO:0008201	heparin binding
0.35	GO:0042802	identical protein binding
0.35	GO:0002020	protease binding
0.35	GO:0005509	calcium ion binding

0.63	GO:0005581	collagen trimer
0.58	GO:0044420	extracellular matrix component
0.55	GO:0005578	proteinaceous extracellular matrix
0.38	GO:0099081	supramolecular polymer
0.37	GO:0005615	extracellular space
0.35	GO:0005694	chromosome
0.35	GO:0031514	motile cilium
0.34	GO:0030056	hemidesmosome
0.34	GO:0005783	endoplasmic reticulum
0.33	GO:0019867	outer membrane

0.37

GO:0004553

tr|T1FPP1|T1FPP1_HELRO
Uncharacterized protein
Search

0.67	Solute carrier family 25 member

0.46	GO:0055085	transmembrane transport
0.41	GO:0006839	mitochondrial transport
0.38	GO:0006828	manganese ion transport
0.36	GO:0031921	pyridoxal phosphate transport
0.35	GO:0006783	heme biosynthetic process
0.32	GO:0016310	phosphorylation

0.38	GO:0016530	metallochaperone activity
0.36	GO:0022857	transmembrane transporter activity
0.34	GO:0030170	pyridoxal phosphate binding
0.33	GO:0005509	calcium ion binding
0.32	GO:0016301	kinase activity

0.39	GO:0005739	mitochondrion
0.38	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

tr|T1FPP2|T1FPP2_HELRO
Uncharacterized protein
Search

0.49	GO:0006606	protein import into nucleus
0.42	GO:0006518	peptide metabolic process
0.42	GO:0044267	cellular protein metabolic process
0.42	GO:0043327	chemotaxis to cAMP
0.41	GO:0099120	socially cooperative development
0.41	GO:0090304	nucleic acid metabolic process
0.40	GO:0016310	phosphorylation
0.40	GO:0006996	organelle organization
0.40	GO:0043604	amide biosynthetic process
0.40	GO:0043038	amino acid activation

0.43	GO:0017076	purine nucleotide binding
0.43	GO:0097367	carbohydrate derivative binding
0.43	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0008144	drug binding
0.42	GO:0000829	inositol heptakisphosphate kinase activity
0.42	GO:0016787	hydrolase activity
0.41	GO:0004832	valine-tRNA ligase activity
0.40	GO:0003723	RNA binding
0.40	GO:0005515	protein binding
0.40	GO:0008270	zinc ion binding

0.44	GO:0019013	viral nucleocapsid
0.39	GO:0044430	cytoskeletal part
0.38	GO:0015629	actin cytoskeleton
0.38	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm
0.36	GO:0043234	protein complex
0.36	GO:0015630	microtubule cytoskeleton
0.30	GO:0016020	membrane

0.42	EC:3	GO:0016787
0.41	KEGG:R03665	GO:0004832

tr|T1FPP3|T1FPP3_HELRO
Uncharacterized protein
Search

0.57	GO:0043065	positive regulation of apoptotic process
0.42	GO:0045493	xylan catabolic process
0.41	GO:0007422	peripheral nervous system development
0.40	GO:0061564	axon development
0.39	GO:0016203	muscle attachment
0.39	GO:0006030	chitin metabolic process
0.39	GO:0106030	neuron projection fasciculation
0.38	GO:0019226	transmission of nerve impulse
0.38	GO:0042552	myelination
0.38	GO:0006508	proteolysis

0.43	GO:0031176	endo-1,4-beta-xylanase activity
0.38	GO:0008061	chitin binding
0.38	GO:0003723	RNA binding
0.38	GO:0140096	catalytic activity, acting on a protein
0.38	GO:0030248	cellulose binding
0.36	GO:0003779	actin binding
0.36	GO:0005509	calcium ion binding
0.36	GO:0017171	serine hydrolase activity
0.35	GO:0003677	DNA binding
0.35	GO:0005198	structural molecule activity

0.42	GO:0005634	nucleus
0.40	GO:0005576	extracellular region
0.40	GO:0033202	DNA helicase complex
0.40	GO:0031974	membrane-enclosed lumen
0.39	GO:0000785	chromatin
0.38	GO:1904949	ATPase complex
0.38	GO:0043025	neuronal cell body
0.37	GO:0030424	axon
0.36	GO:0005856	cytoskeleton
0.34	GO:0005886	plasma membrane

0.43

EC:3.2.1.8

GO:0031176

tr|T1FPP4|T1FPP4_HELRO
Uncharacterized protein
Search

tr|T1FPP5|T1FPP5_HELRO
Uncharacterized protein
Search

tr|T1FPP6|T1FPP6_HELRO
Uncharacterized protein
Search

0.44	GO:1902463	protein localization to cell leading edge
0.42	GO:0008298	intracellular mRNA localization
0.42	GO:1903506	regulation of nucleic acid-templated transcription
0.42	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.41	GO:0010468	regulation of gene expression
0.40	GO:0036211	protein modification process
0.40	GO:0043547	positive regulation of GTPase activity
0.40	GO:0006281	DNA repair
0.39	GO:0016310	phosphorylation
0.39	GO:0098732	macromolecule deacylation

0.46	GO:0003676	nucleic acid binding
0.42	GO:0070492	oligosaccharide binding
0.41	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.40	GO:0004325	ferrochelatase activity
0.40	GO:0016301	kinase activity
0.40	GO:0005096	GTPase activator activity
0.40	GO:0032041	NAD-dependent histone deacetylase activity (H3-K14 specific)
0.39	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.39	GO:0003700	DNA binding transcription factor activity
0.38	GO:0032559	adenyl ribonucleotide binding

0.43	GO:0005634	nucleus
0.41	GO:0031252	cell leading edge
0.36	GO:0005886	plasma membrane
0.34	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.41	EC:2.7.1	GO:0016773
0.40	KEGG:R00310	GO:0004325

tr|T1FPP7|T1FPP7_HELRO
Uncharacterized protein
Search

tr|T1FPP8|T1FPP8_HELRO
Uncharacterized protein
Search

0.57	Splicing factor 1

0.75	GO:0000398	mRNA splicing, via spliceosome
0.40	GO:0033327	Leydig cell differentiation
0.40	GO:0030575	nuclear body organization
0.40	GO:0030238	male sex determination
0.39	GO:0050810	regulation of steroid biosynthetic process
0.36	GO:0000413	protein peptidyl-prolyl isomerization
0.35	GO:0006457	protein folding
0.34	GO:0048662	negative regulation of smooth muscle cell proliferation
0.34	GO:0060041	retina development in camera-type eye
0.33	GO:0022618	ribonucleoprotein complex assembly

0.85	GO:0045131	pre-mRNA branch point binding
0.62	GO:0008270	zinc ion binding
0.37	GO:0042802	identical protein binding
0.36	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.34	GO:0003714	transcription corepressor activity
0.33	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.33	GO:0046983	protein dimerization activity
0.32	GO:0008047	enzyme activator activity

0.40	GO:0005681	spliceosomal complex
0.38	GO:0016604	nuclear body
0.36	GO:0005829	cytosol
0.32	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.36

EC:5.2.1.8

GO:0003755

tr|T1FPP9|T1FPP9_HELRO
Uncharacterized protein
Search

tr|T1FPQ0|T1FPQ0_HELRO
Uncharacterized protein
Search

0.66	GO:0006397	mRNA processing
0.49	GO:0008298	intracellular mRNA localization
0.40	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.39	GO:0051028	mRNA transport
0.38	GO:0008380	RNA splicing
0.38	GO:0006417	regulation of translation
0.38	GO:0007264	small GTPase mediated signal transduction
0.36	GO:0065009	regulation of molecular function
0.35	GO:0006464	cellular protein modification process
0.34	GO:0016310	phosphorylation

0.56	GO:0003723	RNA binding
0.47	GO:0031625	ubiquitin protein ligase binding
0.45	GO:0042802	identical protein binding
0.38	GO:0005085	guanyl-nucleotide exchange factor activity
0.35	GO:0004672	protein kinase activity
0.34	GO:0003779	actin binding
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0008417	fucosyltransferase activity
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0008144	drug binding

0.80	GO:0035145	exon-exon junction complex
0.47	GO:0031965	nuclear membrane
0.41	GO:0030529	intracellular ribonucleoprotein complex
0.39	GO:0030425	dendrite
0.39	GO:0016607	nuclear speck
0.39	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0043232	intracellular non-membrane-bounded organelle
0.34	GO:0020011	apicoplast
0.34	GO:0032580	Golgi cisterna membrane
0.33	GO:0005829	cytosol

0.34

GO:0008417

tr|T1FPQ1|T1FPQ1_HELRO
Uncharacterized protein
Search

tr|T1FPQ2|T1FPQ2_HELRO
Uncharacterized protein
Search

0.73	Troponin i

0.40

GO:0006936

muscle contraction

0.84

GO:0005861

troponin complex

tr|T1FPQ3|T1FPQ3_HELRO
Uncharacterized protein
Search

0.40	GO:0001700	embryonic development via the syncytial blastoderm
0.35	GO:0007399	nervous system development
0.35	GO:0030154	cell differentiation
0.33	GO:0050919	negative chemotaxis
0.32	GO:0006366	transcription by RNA polymerase II
0.32	GO:0045944	positive regulation of transcription by RNA polymerase II
0.32	GO:0016567	protein ubiquitination
0.32	GO:0007018	microtubule-based movement
0.32	GO:0055085	transmembrane transport
0.32	GO:0016310	phosphorylation

0.43	GO:0030215	semaphorin receptor binding
0.32	GO:0001085	RNA polymerase II transcription factor binding
0.32	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.32	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.32	GO:0003682	chromatin binding
0.32	GO:0004842	ubiquitin-protein transferase activity
0.32	GO:0022857	transmembrane transporter activity
0.32	GO:0003777	microtubule motor activity
0.32	GO:0008061	chitin binding
0.32	GO:0046914	transition metal ion binding

0.39	GO:0005887	integral component of plasma membrane
0.34	GO:0005829	cytosol
0.32	GO:0005615	extracellular space
0.32	GO:0020011	apicoplast
0.32	GO:0005667	transcription factor complex
0.32	GO:0005634	nucleus

0.32	EC:1.14	GO:0016705
0.32	KEGG:R03876	GO:0004842

tr|T1FPQ4|T1FPQ4_HELRO
Uncharacterized protein
Search

tr|T1FPQ5|T1FPQ5_HELRO
Uncharacterized protein
Search

tr|T1FPQ6|T1FPQ6_HELRO
Uncharacterized protein
Search

NR2C2AP

0.88	Galactose-binding domain-containing protein

0.39	GO:0006367	transcription initiation from RNA polymerase II promoter
0.37	GO:0007155	cell adhesion
0.36	GO:0042254	ribosome biogenesis
0.36	GO:0006396	RNA processing

0.39	GO:0005540	hyaluronic acid binding
0.36	GO:0005515	protein binding
0.30	GO:0003824	catalytic activity

0.66	GO:0005654	nucleoplasm
0.42	GO:0070062	extracellular exosome
0.37	GO:0005730	nucleolus

tr|T1FPQ7|T1FPQ7_HELRO
Uncharacterized protein
Search

0.39	GO:0051569	regulation of histone H3-K4 methylation
0.39	GO:0006458	'de novo' protein folding
0.38	GO:0016925	protein sumoylation
0.38	GO:0042147	retrograde transport, endosome to Golgi
0.38	GO:0061077	chaperone-mediated protein folding
0.38	GO:0006629	lipid metabolic process
0.38	GO:0030097	hemopoiesis
0.38	GO:0009190	cyclic nucleotide biosynthetic process
0.36	GO:1901575	organic substance catabolic process
0.35	GO:0035556	intracellular signal transduction

0.40	GO:0000285	1-phosphatidylinositol-3-phosphate 5-kinase activity
0.39	GO:0044183	protein binding involved in protein folding
0.39	GO:0031386	protein tag
0.37	GO:0016849	phosphorus-oxygen lyase activity
0.37	GO:0051082	unfolded protein binding
0.37	GO:1901265	nucleoside phosphate binding
0.37	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups
0.36	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.36	GO:0036094	small molecule binding
0.36	GO:0003676	nucleic acid binding

0.38	GO:0010008	endosome membrane
0.36	GO:0005829	cytosol
0.35	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.40	EC:2.7.1.150	GO:0000285
0.40	KEGG:R05802	GO:0000285

tr|T1FPQ8|T1FPQ8_HELRO
Uncharacterized protein
Search

BBS4

0.95	Bardet-Biedl syndrome 4 protein homolog

0.85	GO:0035845	photoreceptor cell outer segment organization
0.81	GO:0038108	negative regulation of appetite by leptin-mediated signaling pathway
0.81	GO:0060613	fat pad development
0.81	GO:0060295	regulation of cilium movement involved in cell motility
0.81	GO:1903546	protein localization to photoreceptor outer segment
0.80	GO:1902855	regulation of non-motile cilium assembly
0.80	GO:0046548	retinal rod cell development
0.79	GO:0003356	regulation of cilium beat frequency
0.79	GO:0003085	negative regulation of systemic arterial blood pressure
0.79	GO:0021756	striatum development

0.80	GO:0034452	dynactin binding
0.77	GO:0001103	RNA polymerase II repressing transcription factor binding
0.77	GO:0043014	alpha-tubulin binding
0.74	GO:0048487	beta-tubulin binding
0.67	GO:0003777	microtubule motor activity

0.80	GO:0034451	centriolar satellite
0.78	GO:0000242	pericentriolar material
0.77	GO:0060170	ciliary membrane
0.77	GO:0001917	photoreceptor inner segment
0.76	GO:0032391	photoreceptor connecting cilium
0.76	GO:0034464	BBSome
0.75	GO:0001750	photoreceptor outer segment
0.73	GO:0036064	ciliary basal body
0.73	GO:0005814	centriole
0.73	GO:0031514	motile cilium

tr|T1FPQ9|T1FPQ9_HELRO
Uncharacterized protein
Search

0.37	GO:0030001	metal ion transport
0.36	GO:0006468	protein phosphorylation
0.35	GO:0055085	transmembrane transport

0.37	GO:0046873	metal ion transmembrane transporter activity
0.36	GO:0004672	protein kinase activity
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0097367	carbohydrate derivative binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding

0.35	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

tr|T1FPR0|T1FPR0_HELRO
Uncharacterized protein
Search

0.40	GO:0065007	biological regulation
0.40	GO:0036211	protein modification process
0.39	GO:0044267	cellular protein metabolic process
0.38	GO:0023052	signaling
0.38	GO:0007154	cell communication
0.38	GO:0050896	response to stimulus
0.37	GO:0006996	organelle organization
0.37	GO:0016311	dephosphorylation
0.36	GO:0097659	nucleic acid-templated transcription
0.36	GO:1901998	toxin transport

0.40	GO:0046872	metal ion binding
0.39	GO:0140110	transcription regulator activity
0.39	GO:0140096	catalytic activity, acting on a protein
0.38	GO:0038023	signaling receptor activity
0.38	GO:0030234	enzyme regulator activity
0.37	GO:0016740	transferase activity
0.37	GO:0005515	protein binding
0.37	GO:0016791	phosphatase activity
0.37	GO:0099600	transmembrane receptor activity
0.36	GO:0003676	nucleic acid binding

0.39	GO:0005634	nucleus
0.36	GO:0010494	cytoplasmic stress granule
0.36	GO:0070013	intracellular organelle lumen
0.34	GO:0043234	protein complex
0.34	GO:0000428	DNA-directed RNA polymerase complex
0.34	GO:0044446	intracellular organelle part
0.34	GO:0005829	cytosol
0.33	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.37

GO:0016740

tr|T1FPR1|T1FPR1_HELRO
Uncharacterized protein
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tr|T1FPR2|T1FPR2_HELRO
Uncharacterized protein
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LANCL1

0.82	LanC lantibiotic synthetase component C-like 2 (Bacterial)

0.52	GO:0009789	positive regulation of abscisic acid-activated signaling pathway
0.48	GO:0007165	signal transduction
0.45	GO:0045892	negative regulation of transcription, DNA-templated

0.81	GO:0050750	low-density lipoprotein particle receptor binding
0.79	GO:0043295	glutathione binding
0.74	GO:0017124	SH3 domain binding
0.59	GO:0008270	zinc ion binding
0.51	GO:0010314	phosphatidylinositol-5-phosphate binding
0.49	GO:0070273	phosphatidylinositol-4-phosphate binding
0.49	GO:0032266	phosphatidylinositol-3-phosphate binding

0.48	GO:0030864	cortical actin cytoskeleton
0.48	GO:0005886	plasma membrane
0.44	GO:0005829	cytosol
0.41	GO:0005634	nucleus

tr|T1FPR3|T1FPR3_HELRO
Uncharacterized protein
Search

tr|T1FPR4|T1FPR4_HELRO
Uncharacterized protein
Search

0.10	Propionyl-CoA carboxylase alpha chain, mitochondrial

0.37	GO:0006508	proteolysis
0.35	GO:0007015	actin filament organization
0.34	GO:0055114	oxidation-reduction process

0.76	GO:0004075	biotin carboxylase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0046872	metal ion binding
0.42	GO:0008241	peptidyl-dipeptidase activity
0.39	GO:0004180	carboxypeptidase activity
0.38	GO:0008237	metallopeptidase activity
0.38	GO:0004658	propionyl-CoA carboxylase activity
0.35	GO:0032403	protein complex binding

0.36	GO:0031209	SCAR complex
0.33	GO:0005759	mitochondrial matrix
0.30	GO:0016020	membrane

0.76

EC:6.3.4.14

GO:0004075

tr|T1FPR5|T1FPR5_HELRO
Uncharacterized protein
Search

tr|T1FPR6|T1FPR6_HELRO
Uncharacterized protein
Search

0.74	GO:0043547	positive regulation of GTPase activity
0.37	GO:0033036	macromolecule localization
0.36	GO:0071702	organic substance transport
0.36	GO:0042886	amide transport
0.36	GO:0042157	lipoprotein metabolic process
0.35	GO:0032940	secretion by cell
0.35	GO:0048205	COPI coating of Golgi vesicle
0.35	GO:0046907	intracellular transport
0.35	GO:1990542	mitochondrial transmembrane transport
0.34	GO:0007005	mitochondrion organization

0.75	GO:0005096	GTPase activator activity
0.49	GO:0046872	metal ion binding
0.35	GO:0008289	lipid binding

0.42	GO:0005794	Golgi apparatus
0.41	GO:0005829	cytosol
0.36	GO:0005886	plasma membrane
0.35	GO:0005744	mitochondrial inner membrane presequence translocase complex
0.35	GO:0005576	extracellular region
0.35	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.34	GO:0030663	COPI-coated vesicle membrane
0.34	GO:0030120	vesicle coat
0.33	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

tr|T1FPR7|T1FPR7_HELRO
Uncharacterized protein
Search

KYAT3

0.81	Kynurenine--oxoglutarate transaminase

0.78	GO:0097052	L-kynurenine metabolic process
0.51	GO:0006575	cellular modified amino acid metabolic process
0.49	GO:0009058	biosynthetic process
0.48	GO:0006103	2-oxoglutarate metabolic process
0.36	GO:0000398	mRNA splicing, via spliceosome
0.35	GO:0042182	ketone catabolic process
0.34	GO:1901606	alpha-amino acid catabolic process
0.34	GO:1901361	organic cyclic compound catabolic process
0.34	GO:0019439	aromatic compound catabolic process
0.33	GO:0006558	L-phenylalanine metabolic process

0.84	GO:0036137	kynurenine aminotransferase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.65	GO:0047804	cysteine-S-conjugate beta-lyase activity
0.57	GO:0070548	L-glutamine aminotransferase activity
0.46	GO:0042803	protein homodimerization activity
0.36	GO:0047312	L-phenylalanine:pyruvate aminotransferase activity
0.35	GO:0003723	RNA binding
0.34	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity
0.33	GO:0046872	metal ion binding

0.41	GO:0043231	intracellular membrane-bounded organelle
0.41	GO:0044444	cytoplasmic part
0.39	GO:0070013	intracellular organelle lumen
0.38	GO:0044446	intracellular organelle part
0.34	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.65	EC:4.4.1.13	GO:0047804
0.36	KEGG:R00692	GO:0047312

tr|T1FPR8|T1FPR8_HELRO
Uncharacterized protein
Search

0.67	Cysteine conjugate-beta lyase; cytoplasmic (Glutamine transaminase K, kyneurenine aminotransferase)

0.70	GO:0097052	L-kynurenine metabolic process
0.53	GO:0006575	cellular modified amino acid metabolic process
0.49	GO:0009058	biosynthetic process
0.42	GO:0006103	2-oxoglutarate metabolic process
0.37	GO:0034275	kynurenic acid metabolic process
0.36	GO:0042182	ketone catabolic process
0.35	GO:1901606	alpha-amino acid catabolic process
0.34	GO:1901361	organic cyclic compound catabolic process
0.34	GO:0019439	aromatic compound catabolic process
0.33	GO:0009072	aromatic amino acid family metabolic process

0.75	GO:0036137	kynurenine aminotransferase activity
0.67	GO:0047804	cysteine-S-conjugate beta-lyase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.59	GO:0070548	L-glutamine aminotransferase activity
0.41	GO:0042803	protein homodimerization activity
0.37	GO:0047312	L-phenylalanine:pyruvate aminotransferase activity
0.37	GO:0047536	2-aminoadipate transaminase activity
0.34	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity
0.33	GO:0033854	glutamate-prephenate aminotransferase activity
0.33	GO:0033853	aspartate-prephenate aminotransferase activity

0.40	GO:0005654	nucleoplasm
0.40	GO:0005829	cytosol
0.38	GO:0005739	mitochondrion
0.32	GO:0009570	chloroplast stroma

0.67	EC:4.4.1.13	GO:0047804
0.37	KEGG:R00692	GO:0047312

tr|T1FPR9|T1FPR9_HELRO
Uncharacterized protein
Search

0.37	GO:0007517	muscle organ development
0.36	GO:0006396	RNA processing
0.34	GO:0032259	methylation
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:0010468	regulation of gene expression

0.79	GO:0017056	structural constituent of nuclear pore
0.35	GO:0003723	RNA binding
0.35	GO:0046983	protein dimerization activity
0.34	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
0.34	GO:0008168	methyltransferase activity
0.33	GO:0003677	DNA binding

0.36	GO:0005634	nucleus
0.35	GO:0043233	organelle lumen
0.34	GO:0043232	intracellular non-membrane-bounded organelle
0.34	GO:0044446	intracellular organelle part

0.34

GO:0016747

tr|T1FPS0|T1FPS0_HELRO
Uncharacterized protein
Search

IPO5

0.84	Karyopherin-beta 3 variant

0.68	GO:0006886	intracellular protein transport
0.63	GO:0006610	ribosomal protein import into nucleus
0.62	GO:0006607	NLS-bearing protein import into nucleus
0.55	GO:0042307	positive regulation of protein import into nucleus
0.55	GO:0071230	cellular response to amino acid stimulus
0.37	GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity
0.37	GO:0034260	negative regulation of GTPase activity
0.34	GO:0016032	viral process

0.78	GO:0008536	Ran GTPase binding
0.55	GO:0008139	nuclear localization sequence binding
0.53	GO:0008565	protein transporter activity
0.37	GO:0005095	GTPase inhibitor activity
0.35	GO:0003723	RNA binding

0.56	GO:0005634	nucleus
0.47	GO:0012505	endomembrane system
0.47	GO:0031974	membrane-enclosed lumen
0.44	GO:0031967	organelle envelope
0.44	GO:0031090	organelle membrane
0.41	GO:0005737	cytoplasm
0.35	GO:0097708	intracellular vesicle
0.34	GO:0043234	protein complex
0.34	GO:0043232	intracellular non-membrane-bounded organelle

tr|T1FPS1|T1FPS1_HELRO
Tyrosine-protein kinase
Search

0.33	Tyrosine-protein kinase

0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.49	GO:0007165	signal transduction
0.49	GO:0042127	regulation of cell proliferation
0.47	GO:0032101	regulation of response to external stimulus
0.47	GO:0071226	cellular response to molecule of fungal origin
0.47	GO:0046777	protein autophosphorylation
0.46	GO:0030155	regulation of cell adhesion
0.46	GO:0002554	serotonin secretion by platelet
0.46	GO:0090237	regulation of arachidonic acid secretion
0.46	GO:2000026	regulation of multicellular organismal development

0.76	GO:0004713	protein tyrosine kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0035325	Toll-like receptor binding
0.44	GO:0042169	SH2 domain binding
0.44	GO:0001784	phosphotyrosine residue binding
0.43	GO:0005178	integrin binding
0.43	GO:0019902	phosphatase binding

0.48	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.46	GO:0032009	early phagosome
0.45	GO:0019815	B cell receptor complex
0.44	GO:0042101	T cell receptor complex
0.42	GO:0005925	focal adhesion
0.41	GO:0005856	cytoskeleton
0.38	GO:0005634	nucleus
0.34	GO:0005829	cytosol
0.33	GO:0030673	axolemma
0.33	GO:0031430	M band

0.76

GO:0004713

tr|T1FPS2|T1FPS2_HELRO
Uncharacterized protein
Search

0.48	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA
0.45	GO:0043085	positive regulation of catalytic activity
0.43	GO:2001141	regulation of RNA biosynthetic process
0.43	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.37	GO:0006468	protein phosphorylation
0.37	GO:0097466	ubiquitin-dependent glycoprotein ERAD pathway
0.37	GO:0031087	deadenylation-independent decapping of nuclear-transcribed mRNA
0.37	GO:0006491	N-glycan processing
0.36	GO:0030968	endoplasmic reticulum unfolded protein response
0.36	GO:0006629	lipid metabolic process

0.46	GO:0008047	enzyme activator activity
0.45	GO:0003700	DNA binding transcription factor activity
0.38	GO:0003676	nucleic acid binding
0.38	GO:0004672	protein kinase activity
0.37	GO:0046872	metal ion binding
0.36	GO:0008536	Ran GTPase binding
0.36	GO:0004932	mating-type factor pheromone receptor activity
0.36	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
0.36	GO:0016788	hydrolase activity, acting on ester bonds
0.36	GO:0030554	adenyl nucleotide binding

0.39	GO:0005634	nucleus
0.36	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex
0.36	GO:0000932	P-body
0.36	GO:0012505	endomembrane system
0.35	GO:0044433	cytoplasmic vesicle part
0.34	GO:0098805	whole membrane
0.34	GO:0098588	bounding membrane of organelle
0.34	GO:0031984	organelle subcompartment
0.33	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.36	EC:3.2.1.113	GO:0004571
0.36	KEGG:R05982 KEGG:R06722	GO:0004571

tr|T1FPS3|T1FPS3_HELRO
Uncharacterized protein
Search

0.47	GO:0060290	transdifferentiation
0.45	GO:0090068	positive regulation of cell cycle process
0.45	GO:0003310	pancreatic A cell differentiation
0.45	GO:0061104	adrenal chromaffin cell differentiation
0.44	GO:0003309	type B pancreatic cell differentiation
0.44	GO:0003358	noradrenergic neuron development
0.44	GO:0042421	norepinephrine biosynthetic process
0.44	GO:0071156	regulation of cell cycle arrest
0.44	GO:0061549	sympathetic ganglion development
0.43	GO:2000179	positive regulation of neural precursor cell proliferation

0.51	GO:0003676	nucleic acid binding
0.43	GO:0042826	histone deacetylase binding
0.43	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.42	GO:0003682	chromatin binding
0.42	GO:0030332	cyclin binding
0.40	GO:0001085	RNA polymerase II transcription factor binding
0.36	GO:0046872	metal ion binding
0.34	GO:0005096	GTPase activator activity
0.33	GO:0003714	transcription corepressor activity

0.44	GO:0017053	transcriptional repressor complex
0.41	GO:0005634	nucleus
0.33	GO:0005829	cytosol
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0044446	intracellular organelle part

tr|T1FPS4|T1FPS4_HELRO
Uncharacterized protein
Search

tr|T1FPS5|T1FPS5_HELRO
Uncharacterized protein
Search

tr|T1FPS6|T1FPS6_HELRO
Uncharacterized protein
Search

tr|T1FPS7|T1FPS7_HELRO
Uncharacterized protein
Search

0.70	GO:0006289	nucleotide-excision repair
0.64	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.52	GO:0036297	interstrand cross-link repair
0.33	GO:0000256	allantoin catabolic process

0.70	GO:0003697	single-stranded DNA binding
0.64	GO:0004518	nuclease activity
0.33	GO:0140097	catalytic activity, acting on DNA
0.33	GO:0004037	allantoicase activity
0.33	GO:0046872	metal ion binding

0.60

GO:0005634

nucleus

0.64	EC:3.1	GO:0004518
0.33	KEGG:R02422	GO:0004037

tr|T1FPS8|T1FPS8_HELRO
Uncharacterized protein
Search

tr|T1FPS9|T1FPS9_HELRO
Uncharacterized protein
Search

0.45	GO:0009968	negative regulation of signal transduction
0.44	GO:0045893	positive regulation of transcription, DNA-templated
0.44	GO:0030727	germarium-derived female germ-line cyst formation
0.44	GO:0007526	larval somatic muscle development
0.43	GO:0030718	germ-line stem cell population maintenance
0.43	GO:0007528	neuromuscular junction development
0.42	GO:0030100	regulation of endocytosis
0.42	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.41	GO:0006281	DNA repair
0.40	GO:0006357	regulation of transcription by RNA polymerase II

0.44	GO:0003682	chromatin binding
0.43	GO:0035035	histone acetyltransferase binding
0.43	GO:0003677	DNA binding
0.42	GO:0030515	snoRNA binding
0.42	GO:0050825	ice binding
0.41	GO:0001067	regulatory region nucleic acid binding
0.40	GO:0045735	nutrient reservoir activity
0.39	GO:0046983	protein dimerization activity
0.38	GO:0016757	transferase activity, transferring glycosyl groups
0.36	GO:0016301	kinase activity

0.47	GO:0005634	nucleus
0.43	GO:0005705	polytene chromosome interband
0.41	GO:0031248	protein acetyltransferase complex
0.39	GO:0043233	organelle lumen
0.38	GO:0005737	cytoplasm
0.37	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

0.38

GO:0016757

tr|T1FPT0|T1FPT0_HELRO
Uncharacterized protein
Search

MCU

0.94	Mitochondrial calcium uniporter

0.57	GO:0036444	mitochondrial calcium uptake
0.56	GO:0051560	mitochondrial calcium ion homeostasis
0.54	GO:0035786	protein complex oligomerization
0.53	GO:0032024	positive regulation of insulin secretion
0.52	GO:0019722	calcium-mediated signaling
0.51	GO:0042593	glucose homeostasis
0.35	GO:0060027	convergent extension involved in gastrulation
0.34	GO:0008016	regulation of heart contraction
0.34	GO:0043009	chordate embryonic development
0.34	GO:0007015	actin filament organization

0.58	GO:0015292	uniporter activity
0.52	GO:0005262	calcium channel activity
0.47	GO:0042802	identical protein binding

0.57	GO:1990246	uniplex complex
0.53	GO:0031305	integral component of mitochondrial inner membrane

tr|T1FPT1|T1FPT1_HELRO
Uncharacterized protein
Search

tr|T1FPT2|T1FPT2_HELRO
Uncharacterized protein
Search

tr|T1FPT3|T1FPT3_HELRO
Uncharacterized protein
Search

0.40	GO:0051493	regulation of cytoskeleton organization
0.39	GO:0007010	cytoskeleton organization
0.38	GO:0005975	carbohydrate metabolic process
0.38	GO:0043547	positive regulation of GTPase activity
0.38	GO:0032970	regulation of actin filament-based process
0.38	GO:0097435	supramolecular fiber organization
0.37	GO:0030029	actin filament-based process
0.37	GO:0045840	positive regulation of mitotic nuclear division
0.37	GO:0000082	G1/S transition of mitotic cell cycle
0.37	GO:0099120	socially cooperative development

0.52	GO:0046872	metal ion binding
0.41	GO:0017056	structural constituent of nuclear pore
0.39	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.39	GO:0008092	cytoskeletal protein binding
0.38	GO:0030246	carbohydrate binding
0.38	GO:0017016	Ras GTPase binding
0.37	GO:0098772	molecular function regulator
0.37	GO:0098748	endocytic adaptor activity
0.36	GO:0008061	chitin binding
0.36	GO:0043130	ubiquitin binding

0.38	GO:0005938	cell cortex
0.38	GO:0005576	extracellular region
0.37	GO:0044430	cytoskeletal part
0.36	GO:0005634	nucleus
0.36	GO:0015630	microtubule cytoskeleton
0.35	GO:0015629	actin cytoskeleton
0.35	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.39

GO:0004553

tr|T1FPT4|T1FPT4_HELRO
Uncharacterized protein
Search

0.38	GO:0030574	collagen catabolic process
0.37	GO:0015074	DNA integration
0.36	GO:0010951	negative regulation of endopeptidase activity
0.36	GO:0007155	cell adhesion
0.36	GO:0007229	integrin-mediated signaling pathway
0.33	GO:0055114	oxidation-reduction process

0.54	GO:0005509	calcium ion binding
0.46	GO:0005201	extracellular matrix structural constituent
0.37	GO:0004867	serine-type endopeptidase inhibitor activity
0.35	GO:0005515	protein binding
0.34	GO:0003676	nucleic acid binding

0.54	GO:0005581	collagen trimer
0.46	GO:0005578	proteinaceous extracellular matrix
0.30	GO:0016020	membrane

tr|T1FPT5|T1FPT5_HELRO
Uncharacterized protein
Search

tr|T1FPT6|T1FPT6_HELRO
Uncharacterized protein
Search

tr|T1FPT7|T1FPT7_HELRO
Uncharacterized protein
Search

0.39	GO:0051685	maintenance of ER location
0.38	GO:0061817	endoplasmic reticulum-plasma membrane tethering
0.36	GO:0070972	protein localization to endoplasmic reticulum
0.34	GO:0030968	endoplasmic reticulum unfolded protein response
0.34	GO:0006874	cellular calcium ion homeostasis
0.33	GO:0008654	phospholipid biosynthetic process

0.39	GO:0033149	FFAT motif binding
0.36	GO:0046875	ephrin receptor binding

0.72	GO:0005789	endoplasmic reticulum membrane
0.41	GO:0005856	cytoskeleton
0.33	GO:0005794	Golgi apparatus
0.33	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

tr|T1FPT8|T1FPT8_HELRO
Uncharacterized protein
Search

PSMD8

0.73	Epididymis secretory sperm binding protein Li 91n

0.61	GO:0006508	proteolysis
0.51	GO:1903955	positive regulation of protein targeting to mitochondrion
0.48	GO:0031647	regulation of protein stability
0.45	GO:0043248	proteasome assembly
0.44	GO:0043632	modification-dependent macromolecule catabolic process
0.43	GO:0044257	cellular protein catabolic process
0.40	GO:0009405	pathogenesis
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.35	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle

0.41

GO:0090729

toxin activity

0.81	GO:0005838	proteasome regulatory particle
0.41	GO:0005829	cytosol
0.39	GO:0005634	nucleus
0.37	GO:0070062	extracellular exosome
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part

tr|T1FPT9|T1FPT9_HELRO
Uncharacterized protein
Search

0.52	GO:0016310	phosphorylation
0.42	GO:0007165	signal transduction

0.54	GO:0016301	kinase activity
0.40	GO:0004386	helicase activity

0.46	GO:0070701	mucus layer
0.30	GO:0031224	intrinsic component of membrane

tr|T1FPU0|T1FPU0_HELRO
Uncharacterized protein
Search

0.52	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.52	GO:0016310	phosphorylation
0.43	GO:0007165	signal transduction

0.54

GO:0016301

kinase activity

0.53	GO:0014069	postsynaptic density
0.52	GO:0031463	Cul3-RING ubiquitin ligase complex
0.52	GO:0043025	neuronal cell body
0.50	GO:0043005	neuron projection

tr|T1FPU1|T1FPU1_HELRO
Uncharacterized protein
Search

0.57	GO:0000266	mitochondrial fission
0.51	GO:0016567	protein ubiquitination
0.41	GO:0030433	ubiquitin-dependent ERAD pathway

0.51	GO:0004842	ubiquitin-protein transferase activity
0.45	GO:0061659	ubiquitin-like protein ligase activity
0.45	GO:0008270	zinc ion binding
0.42	GO:0003723	RNA binding
0.42	GO:0016874	ligase activity

0.42	GO:0000836	Hrd1p ubiquitin ligase complex
0.30	GO:0016021	integral component of membrane

0.42	EC:6	GO:0016874
0.51	KEGG:R03876	GO:0004842

tr|T1FPU2|T1FPU2_HELRO
Uncharacterized protein
Search

0.56	Glycine receptor subunit alpha-3

0.63	GO:0006821	chloride transport
0.61	GO:0007165	signal transduction
0.60	GO:0034220	ion transmembrane transport
0.60	GO:0060078	regulation of postsynaptic membrane potential
0.59	GO:0007268	chemical synaptic transmission
0.49	GO:0097112	gamma-aminobutyric acid receptor clustering
0.48	GO:0060013	righting reflex
0.48	GO:0001964	startle response
0.47	GO:0007628	adult walking behavior
0.47	GO:0007340	acrosome reaction

0.76	GO:0005230	extracellular ligand-gated ion channel activity
0.70	GO:0099600	transmembrane receptor activity
0.65	GO:0099095	ligand-gated anion channel activity
0.65	GO:0038023	signaling receptor activity
0.59	GO:0005254	chloride channel activity
0.49	GO:0016594	glycine binding
0.34	GO:0005515	protein binding
0.33	GO:0070001	aspartic-type peptidase activity
0.32	GO:0004175	endopeptidase activity
0.32	GO:0003700	DNA binding transcription factor activity

0.60	GO:0045211	postsynaptic membrane
0.50	GO:0016935	glycine-gated chloride channel complex
0.49	GO:0098982	GABA-ergic synapse
0.37	GO:0030054	cell junction
0.37	GO:1902711	GABA-A receptor complex
0.36	GO:0030425	dendrite
0.33	GO:0043204	perikaryon
0.33	GO:0009897	external side of plasma membrane
0.33	GO:0005783	endoplasmic reticulum

tr|T1FPU3|T1FPU3_HELRO
Uncharacterized protein
Search

0.82	GO:0030010	establishment of cell polarity
0.76	GO:0000226	microtubule cytoskeleton organization
0.63	GO:0006468	protein phosphorylation
0.45	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity
0.44	GO:0010976	positive regulation of neuron projection development
0.44	GO:0050770	regulation of axonogenesis
0.39	GO:0035556	intracellular signal transduction
0.34	GO:0000422	autophagy of mitochondrion
0.34	GO:0001764	neuron migration
0.34	GO:0018210	peptidyl-threonine modification

0.70	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0045296	cadherin binding
0.39	GO:0000287	magnesium ion binding
0.35	GO:0050321	tau-protein kinase activity
0.34	GO:0030295	protein kinase activator activity
0.33	GO:0008289	lipid binding
0.32	GO:0003723	RNA binding

0.46	GO:0097427	microtubule bundle
0.44	GO:0016328	lateral plasma membrane
0.44	GO:0005884	actin filament
0.41	GO:0005654	nucleoplasm
0.33	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.70

GO:0004674

tr|T1FPU4|T1FPU4_HELRO
Uncharacterized protein
Search

tr|T1FPU5|T1FPU5_HELRO
Uncharacterized protein
Search

0.78	GO:0006338	chromatin remodeling
0.65	GO:0006281	DNA repair
0.58	GO:0006351	transcription, DNA-templated
0.45	GO:0010571	positive regulation of nuclear cell cycle DNA replication
0.44	GO:0071479	cellular response to ionizing radiation
0.43	GO:0034644	cellular response to UV
0.43	GO:0030307	positive regulation of cell growth
0.43	GO:2000045	regulation of G1/S transition of mitotic cell cycle
0.43	GO:0051225	spindle assembly
0.42	GO:0000070	mitotic sister chromatid segregation

0.61	GO:0016887	ATPase activity
0.55	GO:0003677	DNA binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0004386	helicase activity
0.44	GO:0043014	alpha-tubulin binding
0.39	GO:0001067	regulatory region nucleic acid binding
0.38	GO:0140097	catalytic activity, acting on DNA

0.79	GO:0031011	Ino80 complex
0.42	GO:0045111	intermediate filament cytoskeleton
0.42	GO:0016604	nuclear body
0.41	GO:0005700	polytene chromosome
0.37	GO:0005886	plasma membrane
0.34	GO:0005747	mitochondrial respiratory chain complex I
0.30	GO:0031224	intrinsic component of membrane

0.61

GO:0016887

tr|T1FPU6|T1FPU6_HELRO
Uncharacterized protein
Search

tr|T1FPU7|T1FPU7_HELRO
Uncharacterized protein
Search

0.43	GO:0016043	cellular component organization
0.43	GO:2001141	regulation of RNA biosynthetic process
0.42	GO:0048207	vesicle targeting, rough ER to cis-Golgi
0.42	GO:0070271	protein complex biogenesis
0.42	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.42	GO:0010468	regulation of gene expression
0.41	GO:0006914	autophagy
0.40	GO:1903013	response to differentiation-inducing factor 1
0.40	GO:0043157	response to cation stress
0.39	GO:0015031	protein transport

0.53	GO:0045735	nutrient reservoir activity
0.46	GO:0003712	transcription cofactor activity
0.42	GO:0005545	1-phosphatidylinositol binding
0.41	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.41	GO:0030276	clathrin binding
0.40	GO:0003700	DNA binding transcription factor activity
0.39	GO:0003677	DNA binding
0.38	GO:0004842	ubiquitin-protein transferase activity
0.38	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.38	GO:0003779	actin binding

0.46	GO:0005634	nucleus
0.44	GO:0070013	intracellular organelle lumen
0.42	GO:0044446	intracellular organelle part
0.42	GO:0043234	protein complex
0.41	GO:0030136	clathrin-coated vesicle
0.40	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.39	GO:0005794	Golgi apparatus
0.39	GO:0098588	bounding membrane of organelle
0.39	GO:0005783	endoplasmic reticulum
0.39	GO:1990234	transferase complex

0.37	EC:3.2.1.24	GO:0004559
0.38	KEGG:R03876	GO:0004842

tr|T1FPU8|T1FPU8_HELRO
Uncharacterized protein
Search

0.46	GO:0032012	regulation of ARF protein signal transduction
0.45	GO:0034968	histone lysine methylation
0.45	GO:0007495	visceral mesoderm-endoderm interaction involved in midgut development
0.42	GO:0098586	cellular response to virus
0.42	GO:0007018	microtubule-based movement
0.41	GO:0065009	regulation of molecular function
0.41	GO:0051607	defense response to virus
0.40	GO:0010628	positive regulation of gene expression
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.46	GO:0005086	ARF guanyl-nucleotide exchange factor activity
0.45	GO:0018024	histone-lysine N-methyltransferase activity
0.42	GO:0003777	microtubule motor activity
0.41	GO:0003676	nucleic acid binding
0.40	GO:0046872	metal ion binding
0.39	GO:0032550	purine ribonucleoside binding
0.39	GO:0019001	guanyl nucleotide binding
0.37	GO:0003700	DNA binding transcription factor activity
0.36	GO:0032555	purine ribonucleotide binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding

0.37	GO:0005634	nucleus
0.36	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.45

EC:2.1.1.43

GO:0018024

tr|T1FPU9|T1FPU9_HELRO
Uncharacterized protein
Search

0.89	homeodomain-interacting protein kinase 2-like isoform X4

0.63	GO:0006468	protein phosphorylation
0.51	GO:0060235	lens induction in camera-type eye
0.50	GO:0050882	voluntary musculoskeletal movement
0.50	GO:0061072	iris morphogenesis
0.50	GO:0060059	embryonic retina morphogenesis in camera-type eye
0.49	GO:0010842	retina layer formation
0.49	GO:0048596	embryonic camera-type eye morphogenesis
0.49	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
0.49	GO:0007628	adult walking behavior
0.48	GO:0043388	positive regulation of DNA binding

0.64	GO:0004672	protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0046790	virion binding
0.49	GO:0003677	DNA binding
0.48	GO:0001105	RNA polymerase II transcription coactivator activity
0.48	GO:0001102	RNA polymerase II activating transcription factor binding
0.47	GO:0003714	transcription corepressor activity

0.47	GO:0016605	PML body
0.45	GO:0090575	RNA polymerase II transcription factor complex
0.36	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|T1FPV0|T1FPV0_HELRO
Uncharacterized protein
Search

0.65	Peptidase M neutral zinc metallopeptidases zinc binding site

0.78	GO:0030148	sphingolipid biosynthetic process
0.50	GO:0055114	oxidation-reduction process
0.47	GO:0006672	ceramide metabolic process
0.44	GO:0046519	sphingoid metabolic process
0.42	GO:0034311	diol metabolic process
0.40	GO:0043604	amide biosynthetic process
0.36	GO:0046173	polyol biosynthetic process
0.31	GO:0006508	proteolysis

0.81	GO:0042284	sphingolipid delta-4 desaturase activity
0.44	GO:0000170	sphingosine hydroxylase activity
0.33	GO:0004497	monooxygenase activity
0.33	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
0.32	GO:0008235	metalloexopeptidase activity
0.32	GO:0046872	metal ion binding
0.32	GO:0004177	aminopeptidase activity

0.34	GO:0005783	endoplasmic reticulum
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0031984	organelle subcompartment
0.33	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

0.33

GO:0016747

tr|T1FPV1|T1FPV1_HELRO
Uncharacterized protein
Search

tr|T1FPV2|T1FPV2_HELRO
Uncharacterized protein
Search

0.42	GO:0055113	epiboly involved in gastrulation with mouth forming second
0.41	GO:0060972	left/right pattern formation
0.41	GO:0042074	cell migration involved in gastrulation
0.40	GO:0007368	determination of left/right symmetry
0.35	GO:0008039	synaptic target recognition
0.33	GO:0006351	transcription, DNA-templated
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.65	GO:0005509	calcium ion binding
0.33	GO:0043565	sequence-specific DNA binding
0.33	GO:0003700	DNA binding transcription factor activity

0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|T1FPV3|T1FPV3_HELRO
Uncharacterized protein
Search

0.47	GO:1903506	regulation of nucleic acid-templated transcription
0.47	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.47	GO:0010468	regulation of gene expression
0.36	GO:0006366	transcription by RNA polymerase II
0.35	GO:0006526	arginine biosynthetic process
0.35	GO:1902680	positive regulation of RNA biosynthetic process
0.32	GO:0032259	methylation
0.32	GO:0055114	oxidation-reduction process

0.59	GO:0003723	RNA binding
0.36	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.36	GO:0004055	argininosuccinate synthase activity
0.36	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0016706	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0008168	methyltransferase activity

0.34	GO:0005634	nucleus
0.33	GO:0005737	cytoplasm

0.36

EC:6.3.4.5

GO:0004055

tr|T1FPV4|T1FPV4_HELRO
Uncharacterized protein
Search

0.79	GO:0034063	stress granule assembly
0.78	GO:0010603	regulation of cytoplasmic mRNA processing body assembly
0.50	GO:0090328	regulation of olfactory learning
0.50	GO:0097167	circadian regulation of translation
0.50	GO:0051823	regulation of synapse structural plasticity
0.49	GO:0046959	habituation
0.49	GO:0060965	negative regulation of gene silencing by miRNA
0.48	GO:0042051	compound eye photoreceptor development
0.48	GO:0022416	chaeta development
0.48	GO:0045475	locomotor rhythm

0.70	GO:0045296	cadherin binding
0.48	GO:0003723	RNA binding
0.36	GO:0003924	GTPase activity
0.36	GO:0005525	GTP binding
0.35	GO:0004674	protein serine/threonine kinase activity
0.35	GO:0004721	phosphoprotein phosphatase activity
0.35	GO:0003712	transcription cofactor activity
0.34	GO:0031072	heat shock protein binding
0.34	GO:0051087	chaperone binding
0.34	GO:0003777	microtubule motor activity

0.74	GO:0010494	cytoplasmic stress granule
0.69	GO:0016607	nuclear speck
0.60	GO:0005829	cytosol
0.36	GO:0035068	micro-ribonucleoprotein complex
0.35	GO:0000932	P-body
0.35	GO:1990234	transferase complex
0.35	GO:0012505	endomembrane system
0.35	GO:0043234	protein complex
0.35	GO:0030018	Z disc
0.34	GO:0030134	COPII-coated ER to Golgi transport vesicle

0.35

GO:0004674

tr|T1FPV5|T1FPV5_HELRO
Uncharacterized protein
Search

tr|T1FPV6|T1FPV6_HELRO
Uncharacterized protein
Search

tr|T1FPV7|T1FPV7_HELRO
Uncharacterized protein
Search

tr|T1FPV8|T1FPV8_HELRO
Uncharacterized protein
Search

0.67	GO:0009408	response to heat
0.52	GO:0000380	alternative mRNA splicing, via spliceosome
0.50	GO:0007530	sex determination
0.44	GO:0006888	ER to Golgi vesicle-mediated transport
0.43	GO:0061077	chaperone-mediated protein folding
0.43	GO:0007232	osmosensory signaling pathway via Sho1 osmosensor
0.41	GO:0006886	intracellular protein transport
0.41	GO:0006972	hyperosmotic response
0.40	GO:0030010	establishment of cell polarity

0.42	GO:0005034	osmosensor activity
0.41	GO:0003723	RNA binding
0.41	GO:0051082	unfolded protein binding
0.39	GO:0008270	zinc ion binding

0.44	GO:0030127	COPII vesicle coat
0.40	GO:0030427	site of polarized growth
0.39	GO:0009986	cell surface
0.37	GO:0005576	extracellular region
0.35	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1FPV9|T1FPV9_HELRO
Uncharacterized protein
Search

tr|T1FPW0|T1FPW0_HELRO
Uncharacterized protein
Search

tr|T1FPW1|T1FPW1_HELRO
POU domain protein
Search

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.44	GO:1902680	positive regulation of RNA biosynthetic process
0.43	GO:1902679	negative regulation of RNA biosynthetic process
0.36	GO:0060019	radial glial cell differentiation
0.35	GO:0007219	Notch signaling pathway
0.35	GO:0042981	regulation of apoptotic process
0.34	GO:0016073	snRNA metabolic process

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.46	GO:0001047	core promoter binding
0.44	GO:0001012	RNA polymerase II regulatory region DNA binding
0.43	GO:0003690	double-stranded DNA binding
0.36	GO:0001223	transcription coactivator binding

0.61	GO:0005634	nucleus
0.44	GO:0005667	transcription factor complex
0.43	GO:0005783	endoplasmic reticulum
0.42	GO:0043233	organelle lumen
0.39	GO:0044446	intracellular organelle part

tr|T1FPW2|T1FPW2_HELRO
Uncharacterized protein
Search

tr|T1FPW3|T1FPW3_HELRO
Uncharacterized protein
Search

tr|T1FPW4|T1FPW4_HELRO
Uncharacterized protein
Search

tr|T1FPW5|T1FPW5_HELRO
Uncharacterized protein
Search

tr|T1FPW6|T1FPW6_HELRO
Uncharacterized protein
Search

tr|T1FPW7|T1FPW7_HELRO
Uncharacterized protein
Search

tr|T1FPW8|T1FPW8_HELRO
Uncharacterized protein
Search

0.41	GO:0060219	camera-type eye photoreceptor cell differentiation
0.41	GO:0010842	retina layer formation
0.41	GO:0007416	synapse assembly
0.39	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.38	GO:0070647	protein modification by small protein conjugation or removal
0.37	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic
0.36	GO:0031323	regulation of cellular metabolic process
0.36	GO:0051171	regulation of nitrogen compound metabolic process
0.36	GO:0060255	regulation of macromolecule metabolic process
0.36	GO:0080090	regulation of primary metabolic process

0.38	GO:0008270	zinc ion binding
0.37	GO:0003676	nucleic acid binding
0.37	GO:0004534	5'-3' exoribonuclease activity
0.36	GO:0003700	DNA binding transcription factor activity
0.36	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.36	GO:0031386	protein tag
0.36	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.35	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity
0.35	GO:0004842	ubiquitin-protein transferase activity
0.35	GO:0005262	calcium channel activity

0.39	GO:0045202	synapse
0.38	GO:0005634	nucleus
0.36	GO:0098595	perivitelline space
0.36	GO:0030126	COPI vesicle coat
0.34	GO:0005615	extracellular space
0.33	GO:0005694	chromosome
0.33	GO:0005887	integral component of plasma membrane
0.33	GO:0070013	intracellular organelle lumen

0.37	EC:3.1.13	GO:0004534
0.35	KEGG:R03876	GO:0004842

tr|T1FPW9|T1FPW9_HELRO
Uncharacterized protein
Search

tr|T1FPX0|T1FPX0_HELRO
Uncharacterized protein
Search

0.63	GO:0006468	protein phosphorylation
0.54	GO:0007165	signal transduction
0.53	GO:0030536	larval feeding behavior
0.53	GO:2000331	regulation of terminal button organization
0.53	GO:0051124	synaptic growth at neuromuscular junction
0.52	GO:0045793	positive regulation of cell size
0.52	GO:0007525	somatic muscle development
0.52	GO:0007520	myoblast fusion
0.51	GO:0016239	positive regulation of macroautophagy
0.51	GO:0035264	multicellular organism growth

0.70	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005515	protein binding

0.50	GO:0048786	presynaptic active zone
0.39	GO:0005634	nucleus
0.36	GO:0005829	cytosol
0.36	GO:0043233	organelle lumen
0.35	GO:0044446	intracellular organelle part
0.34	GO:0005840	ribosome

0.70

GO:0004674

tr|T1FPX1|T1FPX1_HELRO
Uncharacterized protein
Search

0.53	GO:0045087	innate immune response
0.47	GO:0007165	signal transduction
0.45	GO:0002218	activation of innate immune response
0.45	GO:0006468	protein phosphorylation
0.44	GO:0050729	positive regulation of inflammatory response
0.43	GO:0043330	response to exogenous dsRNA
0.43	GO:0032722	positive regulation of chemokine production
0.43	GO:0098542	defense response to other organism
0.41	GO:0009615	response to virus
0.41	GO:0002252	immune effector process

0.45	GO:0004672	protein kinase activity
0.42	GO:0004888	transmembrane signaling receptor activity
0.41	GO:0003725	double-stranded RNA binding
0.41	GO:0030554	adenyl nucleotide binding
0.41	GO:0097367	carbohydrate derivative binding
0.41	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0008144	drug binding
0.36	GO:0016849	phosphorus-oxygen lyase activity
0.35	GO:0004180	carboxypeptidase activity
0.34	GO:0016874	ligase activity

0.36	GO:0048226	Casparian strip
0.36	GO:0005783	endoplasmic reticulum
0.36	GO:0005615	extracellular space
0.36	GO:0120025	plasma membrane bounded cell projection
0.34	GO:0031252	cell leading edge
0.34	GO:0005887	integral component of plasma membrane

0.36

EC:4.6

GO:0016849

tr|T1FPX2|T1FPX2_HELRO
Uncharacterized protein
Search

tr|T1FPX3|T1FPX3_HELRO
Uncharacterized protein
Search

tr|T1FPX4|T1FPX4_HELRO
Uncharacterized protein
Search

tr|T1FPX5|T1FPX5_HELRO
Uncharacterized protein
Search

0.81	GO:0007517	muscle organ development
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0007518	myoblast fate determination
0.55	GO:1901741	positive regulation of myoblast fusion
0.54	GO:0043503	skeletal muscle fiber adaptation
0.54	GO:0043415	positive regulation of skeletal muscle tissue regeneration
0.54	GO:0071392	cellular response to estradiol stimulus
0.53	GO:0014908	myotube differentiation involved in skeletal muscle regeneration

0.68	GO:0046983	protein dimerization activity
0.55	GO:0003677	DNA binding
0.51	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.51	GO:0035257	nuclear hormone receptor binding
0.50	GO:0001067	regulatory region nucleic acid binding
0.49	GO:0003682	chromatin binding
0.48	GO:0031625	ubiquitin protein ligase binding
0.48	GO:0003713	transcription coactivator activity
0.45	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.36	GO:0005249	voltage-gated potassium channel activity

0.61	GO:0005634	nucleus
0.49	GO:0030016	myofibril
0.48	GO:0005667	transcription factor complex
0.46	GO:0000785	chromatin
0.44	GO:0005829	cytosol
0.44	GO:0070013	intracellular organelle lumen
0.36	GO:0008076	voltage-gated potassium channel complex
0.34	GO:0005581	collagen trimer

tr|T1FPX6|T1FPX6_HELRO
Uncharacterized protein
Search

tr|T1FPX7|T1FPX7_HELRO
Uncharacterized protein
Search

tr|T1FPX8|T1FPX8_HELRO
Uncharacterized protein
Search

0.39	GO:0006508	proteolysis
0.36	GO:0061061	muscle structure development
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:0010468	regulation of gene expression

0.53	GO:0046872	metal ion binding
0.39	GO:0008233	peptidase activity

0.41	GO:0005911	cell-cell junction
0.37	GO:0055120	striated muscle dense body
0.30	GO:0044425	membrane part

0.39

GO:0008233

tr|T1FPX9|T1FPX9_HELRO
Uncharacterized protein
Search

0.77	GO:0070588	calcium ion transmembrane transport
0.46	GO:0016322	neuron remodeling
0.45	GO:0019722	calcium-mediated signaling
0.37	GO:1901385	regulation of voltage-gated calcium channel activity
0.37	GO:0007528	neuromuscular junction development
0.36	GO:0007268	chemical synaptic transmission

0.82

GO:0005245

voltage-gated calcium channel activity

0.81	GO:0005891	voltage-gated calcium channel complex
0.34	GO:0005622	intracellular

tr|T1FPY0|T1FPY0_HELRO
Galactoside 2-alpha-L-fucosyltransferase
Search

0.40	Galactoside 2-alpha-L-fucosyltransferase

0.73	GO:0036065	fucosylation
0.68	GO:0043413	macromolecule glycosylation
0.68	GO:0009101	glycoprotein biosynthetic process
0.56	GO:0005975	carbohydrate metabolic process
0.56	GO:0036211	protein modification process
0.52	GO:0044267	cellular protein metabolic process
0.39	GO:0003008	system process
0.38	GO:0010669	epithelial structure maintenance
0.38	GO:0060177	regulation of angiotensin metabolic process
0.38	GO:0016486	peptide hormone processing

0.77	GO:0008107	galactoside 2-alpha-L-fucosyltransferase activity
0.43	GO:0005509	calcium ion binding
0.40	GO:0008237	metallopeptidase activity
0.39	GO:0008270	zinc ion binding
0.38	GO:0004175	endopeptidase activity
0.37	GO:0005518	collagen binding
0.37	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.36	GO:0004177	aminopeptidase activity
0.36	GO:0030246	carbohydrate binding

0.74	GO:0032580	Golgi cisterna membrane
0.40	GO:0031012	extracellular matrix
0.36	GO:0005618	cell wall
0.30	GO:0016021	integral component of membrane

0.77

EC:2.4.1.69

GO:0008107

tr|T1FPY1|T1FPY1_HELRO
Uncharacterized protein
Search

0.73	GO:0051262	protein tetramerization
0.60	GO:0034220	ion transmembrane transport
0.44	GO:0010960	magnesium ion homeostasis
0.43	GO:0055069	zinc ion homeostasis
0.42	GO:0016049	cell growth
0.41	GO:0007005	mitochondrion organization
0.40	GO:0070838	divalent metal ion transport
0.39	GO:0002724	regulation of T cell cytokine production
0.39	GO:0061337	cardiac conduction
0.39	GO:0042310	vasoconstriction

0.69	GO:0005216	ion channel activity
0.42	GO:0022836	gated channel activity
0.39	GO:0046873	metal ion transmembrane transporter activity
0.33	GO:0004089	carbonate dehydratase activity
0.32	GO:0003700	DNA binding transcription factor activity
0.32	GO:0008270	zinc ion binding

0.41

GO:0034703

cation channel complex

0.33

EC:4.2.1.1

GO:0004089

tr|T1FPY2|T1FPY2_HELRO
Uncharacterized protein
Search

tr|T1FPY3|T1FPY3_HELRO
Uncharacterized protein
Search

tr|T1FPY4|T1FPY4_HELRO
Uncharacterized protein
Search

tr|T1FPY5|T1FPY5_HELRO
Uncharacterized protein
Search

0.46	GO:0006030	chitin metabolic process
0.41	GO:0006508	proteolysis
0.41	GO:0005975	carbohydrate metabolic process
0.38	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.38	GO:0006751	glutathione catabolic process
0.38	GO:0035335	peptidyl-tyrosine dephosphorylation
0.37	GO:0007018	microtubule-based movement
0.35	GO:0032502	developmental process
0.35	GO:0016567	protein ubiquitination
0.35	GO:0043632	modification-dependent macromolecule catabolic process

0.45	GO:0008061	chitin binding
0.45	GO:0030248	cellulose binding
0.43	GO:0004222	metalloendopeptidase activity
0.42	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.41	GO:0008270	zinc ion binding
0.40	GO:0005509	calcium ion binding
0.38	GO:0036374	glutathione hydrolase activity
0.38	GO:0004725	protein tyrosine phosphatase activity
0.37	GO:0003777	microtubule motor activity
0.37	GO:0008017	microtubule binding

0.50	GO:0005576	extracellular region
0.36	GO:0000151	ubiquitin ligase complex
0.35	GO:0005886	plasma membrane
0.34	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.43	EC:3.4.24	GO:0004222
0.38	KEGG:R00494	GO:0036374

tr|T1FPY6|T1FPY6_HELRO
Uncharacterized protein
Search

tr|T1FPY7|T1FPY7_HELRO
Uncharacterized protein
Search

tr|T1FPY8|T1FPY8_HELRO
Uncharacterized protein
Search

tr|T1FPY9|T1FPY9_HELRO
Uncharacterized protein
Search

tr|T1FPZ0|T1FPZ0_HELRO
Uncharacterized protein
Search

tr|T1FPZ1|T1FPZ1_HELRO
Uncharacterized protein
Search

tr|T1FPZ2|T1FPZ2_HELRO
Uncharacterized protein
Search

tr|T1FPZ3|T1FPZ3_HELRO
Uncharacterized protein
Search

tr|T1FPZ4|T1FPZ4_HELRO
Uncharacterized protein
Search

0.43	GO:0060255	regulation of macromolecule metabolic process
0.43	GO:0031323	regulation of cellular metabolic process
0.43	GO:0051171	regulation of nitrogen compound metabolic process
0.43	GO:0080090	regulation of primary metabolic process
0.43	GO:0009889	regulation of biosynthetic process
0.41	GO:0006468	protein phosphorylation
0.39	GO:0006397	mRNA processing
0.37	GO:0007018	microtubule-based movement
0.36	GO:0031098	stress-activated protein kinase signaling cascade
0.36	GO:0051347	positive regulation of transferase activity

0.45	GO:0003700	DNA binding transcription factor activity
0.42	GO:0004674	protein serine/threonine kinase activity
0.40	GO:0003676	nucleic acid binding
0.39	GO:0008270	zinc ion binding
0.38	GO:0032559	adenyl ribonucleotide binding
0.38	GO:0008144	drug binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0003777	microtubule motor activity
0.35	GO:0046982	protein heterodimerization activity
0.35	GO:0004842	ubiquitin-protein transferase activity

0.39	GO:0005634	nucleus
0.36	GO:0020011	apicoplast
0.35	GO:0005667	transcription factor complex
0.35	GO:0044164	host cell cytosol
0.34	GO:0019013	viral nucleocapsid
0.34	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0012505	endomembrane system
0.33	GO:0031967	organelle envelope
0.33	GO:0031090	organelle membrane
0.33	GO:0005886	plasma membrane

0.42	EC:2.7.11	GO:0004674
0.35	KEGG:R03876	GO:0004842

tr|T1FPZ5|T1FPZ5_HELRO
Uncharacterized protein
Search

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0032286	central nervous system myelin maintenance
0.53	GO:0031643	positive regulation of myelination
0.46	GO:1902680	positive regulation of RNA biosynthetic process
0.34	GO:0006508	proteolysis
0.34	GO:0090304	nucleic acid metabolic process
0.34	GO:0006974	cellular response to DNA damage stimulus
0.34	GO:0034654	nucleobase-containing compound biosynthetic process

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.36	GO:0042802	identical protein binding
0.34	GO:0008233	peptidase activity
0.34	GO:0004518	nuclease activity
0.33	GO:0004930	G-protein coupled receptor activity

0.46	GO:0005794	Golgi apparatus
0.45	GO:0005654	nucleoplasm
0.45	GO:0005829	cytosol
0.36	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

0.34

GO:0008233

tr|T1FPZ6|T1FPZ6_HELRO
Uncharacterized protein
Search

tr|T1FPZ7|T1FPZ7_HELRO
Uncharacterized protein
Search

RNF185

0.95	Ring finger protein 185 (Predicted)

0.49	GO:0030433	ubiquitin-dependent ERAD pathway
0.47	GO:0071712	ER-associated misfolded protein catabolic process
0.45	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.45	GO:0051865	protein autoubiquitination
0.38	GO:0006914	autophagy
0.35	GO:1904380	endoplasmic reticulum mannose trimming
0.34	GO:0033137	negative regulation of peptidyl-serine phosphorylation
0.34	GO:0010977	negative regulation of neuron projection development
0.34	GO:0046856	phosphatidylinositol dephosphorylation
0.32	GO:0055085	transmembrane transport

0.51	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway
0.51	GO:0016874	ligase activity
0.50	GO:0044390	ubiquitin-like protein conjugating enzyme binding
0.37	GO:0046872	metal ion binding
0.35	GO:0034485	phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity

0.51	GO:0036513	Derlin-1 retrotranslocation complex
0.38	GO:0005741	mitochondrial outer membrane
0.34	GO:0044322	endoplasmic reticulum quality control compartment
0.34	GO:0043198	dendritic shaft
0.34	GO:0030426	growth cone
0.34	GO:0001726	ruffle
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.51

GO:0016874

tr|T1FPZ8|T1FPZ8_HELRO
Uncharacterized protein
Search

tr|T1FPZ9|T1FPZ9_HELRO
Uncharacterized protein
Search

tr|T1FQ00|T1FQ00_HELRO
Uncharacterized protein
Search

tr|T1FQ01|T1FQ01_HELRO
Uncharacterized protein
Search

tr|T1FQ02|T1FQ02_HELRO
Uncharacterized protein
Search

0.69	GO:0048015	phosphatidylinositol-mediated signaling
0.65	GO:0046854	phosphatidylinositol phosphorylation
0.46	GO:0007017	microtubule-based process
0.43	GO:0030242	autophagy of peroxisome
0.43	GO:0006928	movement of cell or subcellular component
0.43	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process
0.42	GO:0000045	autophagosome assembly
0.41	GO:0016197	endosomal transport
0.40	GO:0006396	RNA processing
0.40	GO:0006897	endocytosis

0.51	GO:0016301	kinase activity
0.45	GO:0003777	microtubule motor activity
0.45	GO:0008017	microtubule binding
0.44	GO:0030492	hemoglobin binding
0.39	GO:0005509	calcium ion binding
0.38	GO:0032559	adenyl ribonucleotide binding
0.38	GO:0008144	drug binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.35	GO:0003676	nucleic acid binding

0.45	GO:0020020	food vacuole
0.44	GO:0034272	phosphatidylinositol 3-kinase complex, class III, type II
0.44	GO:0034271	phosphatidylinositol 3-kinase complex, class III, type I
0.42	GO:0000407	phagophore assembly site
0.41	GO:0005777	peroxisome
0.41	GO:0005768	endosome
0.40	GO:0005874	microtubule
0.38	GO:0043656	intracellular region of host
0.30	GO:0016021	integral component of membrane

0.38

GO:0016773

tr|T1FQ03|T1FQ03_HELRO
Uncharacterized protein
Search

tr|T1FQ04|T1FQ04_HELRO
Uncharacterized protein
Search

0.48	GO:0043213	bacteriocin transport
0.40	GO:0070647	protein modification by small protein conjugation or removal
0.39	GO:0016192	vesicle-mediated transport
0.39	GO:0046907	intracellular transport
0.39	GO:0065007	biological regulation
0.39	GO:0009116	nucleoside metabolic process
0.39	GO:0006996	organelle organization
0.38	GO:0033036	macromolecule localization
0.38	GO:0006511	ubiquitin-dependent protein catabolic process
0.38	GO:0031154	culmination involved in sorocarp development

0.42	GO:0003723	RNA binding
0.41	GO:0050825	ice binding
0.40	GO:0008092	cytoskeletal protein binding
0.40	GO:0003712	transcription cofactor activity
0.40	GO:0005215	transporter activity
0.38	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.37	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding
0.37	GO:0003830	beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity
0.37	GO:0098772	molecular function regulator
0.37	GO:0008168	methyltransferase activity

0.41	GO:0005634	nucleus
0.40	GO:0030123	AP-3 adaptor complex
0.39	GO:0070013	intracellular organelle lumen
0.38	GO:0031248	protein acetyltransferase complex
0.37	GO:0044446	intracellular organelle part
0.37	GO:1902773	GTPase activator complex
0.37	GO:0005764	lysosome
0.36	GO:0043232	intracellular non-membrane-bounded organelle
0.36	GO:1905368	peptidase complex
0.35	GO:0005829	cytosol

0.38	EC:2.4.2.30	GO:0003950
0.36	KEGG:R03876	GO:0004842

tr|T1FQ05|T1FQ05_HELRO
Uncharacterized protein
Search

tr|T1FQ06|T1FQ06_HELRO
Uncharacterized protein
Search

tr|T1FQ07|T1FQ07_HELRO
Uncharacterized protein
Search

0.76	GO:0000226	microtubule cytoskeleton organization
0.44	GO:0008355	olfactory learning
0.43	GO:0060052	neurofilament cytoskeleton organization
0.43	GO:0008582	regulation of synaptic growth at neuromuscular junction
0.43	GO:0008088	axo-dendritic transport
0.42	GO:0048813	dendrite morphogenesis
0.42	GO:0043524	negative regulation of neuron apoptotic process
0.41	GO:0007409	axonogenesis

0.74	GO:0008017	microtubule binding
0.41	GO:0019900	kinase binding

0.73	GO:0005874	microtubule
0.42	GO:0043025	neuronal cell body
0.42	GO:0030425	dendrite
0.41	GO:0030424	axon
0.40	GO:0005875	microtubule associated complex

tr|T1FQ08|T1FQ08_HELRO
Uncharacterized protein
Search

0.41	GO:0044648	histone H3-K4 dimethylation
0.41	GO:1901674	regulation of histone H3-K27 acetylation
0.40	GO:2001040	positive regulation of cellular response to drug
0.40	GO:0048172	regulation of short-term neuronal synaptic plasticity
0.40	GO:0071440	regulation of histone H3-K14 acetylation
0.40	GO:0051571	positive regulation of histone H3-K4 methylation
0.40	GO:0080182	histone H3-K4 trimethylation
0.40	GO:0035640	exploration behavior
0.40	GO:0060216	definitive hemopoiesis
0.40	GO:0043984	histone H4-K16 acetylation

0.40	GO:0045322	unmethylated CpG binding
0.39	GO:0070577	lysine-acetylated histone binding
0.39	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.39	GO:0001046	core promoter sequence-specific DNA binding
0.38	GO:0003682	chromatin binding
0.38	GO:0042803	protein homodimerization activity
0.36	GO:0008270	zinc ion binding

0.39	GO:0071339	MLL1 complex
0.37	GO:0005829	cytosol
0.30	GO:0016020	membrane

tr|T1FQ09|T1FQ09_HELRO
Alpha-tubulin N-acetyltransferase
Search

0.47	Alpha-tubulin N-acetyltransferase

0.86	GO:0071929	alpha-tubulin acetylation
0.76	GO:0070507	regulation of microtubule cytoskeleton organization
0.68	GO:0048666	neuron development
0.39	GO:0048149	behavioral response to ethanol
0.36	GO:1900227	positive regulation of NLRP3 inflammasome complex assembly
0.36	GO:0021542	dentate gyrus development
0.35	GO:0045598	regulation of fat cell differentiation
0.35	GO:0001966	thigmotaxis
0.35	GO:0007283	spermatogenesis
0.33	GO:0045454	cell redox homeostasis

0.86	GO:0019799	tubulin N-acetyltransferase activity
0.38	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor
0.35	GO:0050220	prostaglandin-E synthase activity
0.34	GO:0050662	coenzyme binding
0.33	GO:0015035	protein disulfide oxidoreductase activity
0.33	GO:0009055	electron transfer activity
0.33	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.32	GO:0046982	protein heterodimerization activity
0.32	GO:0003677	DNA binding
0.32	GO:0008270	zinc ion binding

0.73	GO:0005874	microtubule
0.43	GO:0005925	focal adhesion
0.43	GO:0005905	clathrin-coated pit
0.43	GO:0030424	axon
0.42	GO:0005819	spindle
0.36	GO:0097427	microtubule bundle
0.35	GO:0005737	cytoplasm
0.33	GO:0043231	intracellular membrane-bounded organelle
0.32	GO:0005667	transcription factor complex
0.30	GO:0031224	intrinsic component of membrane

0.86	EC:2.3.1.108	GO:0019799
0.35	KEGG:R02265	GO:0050220

tr|T1FQ10|T1FQ10_HELRO
Uncharacterized protein
Search

tr|T1FQ11|T1FQ11_HELRO
Uncharacterized protein
Search

tr|T1FQ12|T1FQ12_HELRO
Uncharacterized protein
Search

tr|T1FQ13|T1FQ13_HELRO
Uncharacterized protein
Search

0.60	GO:0043486	histone exchange
0.55	GO:0017182	peptidyl-diphthamide metabolic process
0.55	GO:1900247	regulation of cytoplasmic translational elongation
0.52	GO:0106074	aminoacyl-tRNA metabolism involved in translational fidelity
0.49	GO:0006418	tRNA aminoacylation for protein translation
0.46	GO:0006468	protein phosphorylation
0.45	GO:1903506	regulation of nucleic acid-templated transcription

0.52	GO:0002161	aminoacyl-tRNA editing activity
0.49	GO:0005509	calcium ion binding
0.49	GO:0016875	ligase activity, forming carbon-oxygen bonds
0.47	GO:0032559	adenyl ribonucleotide binding
0.46	GO:0008144	drug binding
0.46	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0004672	protein kinase activity

0.47

GO:0005634

nucleus

0.49

EC:6.1

GO:0016875

tr|T1FQ14|T1FQ14_HELRO
Uncharacterized protein
Search

tr|T1FQ15|T1FQ15_HELRO
Uncharacterized protein
Search

0.46	GO:0045087	innate immune response
0.42	GO:0007165	signal transduction
0.41	GO:0050707	regulation of cytokine secretion
0.41	GO:0002218	activation of innate immune response
0.40	GO:0098542	defense response to other organism
0.40	GO:0051014	actin filament severing
0.39	GO:0006954	inflammatory response
0.39	GO:0009615	response to virus
0.39	GO:0002252	immune effector process
0.38	GO:0007409	axonogenesis

0.53	GO:0005509	calcium ion binding
0.39	GO:0003727	single-stranded RNA binding
0.39	GO:0051015	actin filament binding
0.39	GO:0003725	double-stranded RNA binding
0.38	GO:0016301	kinase activity
0.37	GO:0001875	lipopolysaccharide receptor activity
0.37	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.36	GO:0140096	catalytic activity, acting on a protein
0.36	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding

0.47	GO:0005576	extracellular region
0.37	GO:0046696	lipopolysaccharide receptor complex
0.33	GO:0005886	plasma membrane

0.37

GO:0016773

tr|T1FQ16|T1FQ16_HELRO
Uncharacterized protein
Search

tr|T1FQ17|T1FQ17_HELRO
Uncharacterized protein
Search

tr|T1FQ18|T1FQ18_HELRO
Uncharacterized protein
Search

tr|T1FQ19|T1FQ19_HELRO
Uncharacterized protein
Search

0.10	Putative patatin-like phospholipase domain-containing protein 7

0.72	GO:0046470	phosphatidylcholine metabolic process
0.72	GO:0016042	lipid catabolic process
0.38	GO:0032502	developmental process
0.35	GO:0034349	glial cell apoptotic process
0.35	GO:2000480	negative regulation of cAMP-dependent protein kinase activity
0.34	GO:0051402	neuron apoptotic process
0.34	GO:0045494	photoreceptor cell maintenance
0.34	GO:0007608	sensory perception of smell
0.33	GO:0072657	protein localization to membrane
0.33	GO:0006643	membrane lipid metabolic process

0.73	GO:0004622	lysophospholipase activity
0.35	GO:0034236	protein kinase A catalytic subunit binding
0.34	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.34	GO:0005044	scavenger receptor activity
0.33	GO:0001871	pattern binding
0.33	GO:0030246	carbohydrate binding

0.38	GO:0005783	endoplasmic reticulum
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0031984	organelle subcompartment
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.73

EC:3.1.1.5

GO:0004622

tr|T1FQ20|T1FQ20_HELRO
Uncharacterized protein
Search

0.78	GO:0008203	cholesterol metabolic process
0.68	GO:0016042	lipid catabolic process
0.45	GO:0006642	triglyceride mobilization
0.34	GO:0019236	response to pheromone
0.33	GO:0007186	G-protein coupled receptor signaling pathway

0.71	GO:0016298	lipase activity
0.33	GO:0052689	carboxylic ester hydrolase activity
0.33	GO:0046983	protein dimerization activity

0.43	GO:0005811	lipid droplet
0.40	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.71	EC:3.1.1	GO:0016298
0.33	KEGG:R00630	GO:0052689

tr|T1FQ21|T1FQ21_HELRO
Uncharacterized protein
Search

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0021524	visceral motor neuron differentiation
0.52	GO:0048665	neuron fate specification
0.51	GO:0031290	retinal ganglion cell axon guidance
0.49	GO:0045665	negative regulation of neuron differentiation
0.40	GO:0031017	exocrine pancreas development
0.40	GO:0048675	axon extension
0.36	GO:0048935	peripheral nervous system neuron development

0.64	GO:0043565	sequence-specific DNA binding
0.53	GO:0046872	metal ion binding
0.46	GO:0042578	phosphoric ester hydrolase activity
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.46

GO:0042578

tr|T1FQ22|T1FQ22_HELRO
Uncharacterized protein
Search

tr|T1FQ23|T1FQ23_HELRO
Uncharacterized protein
Search

0.60	OTU domain-containing protein 6B

0.55	GO:0006508	proteolysis
0.46	GO:0070647	protein modification by small protein conjugation or removal
0.46	GO:0008283	cell proliferation
0.41	GO:0042089	cytokine biosynthetic process

0.56	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.36	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds

0.50	GO:0005829	cytosol
0.30	GO:0044425	membrane part

0.56

EC:3.4.19.12

GO:0036459

tr|T1FQ24|T1FQ24_HELRO
Uncharacterized protein
Search

tr|T1FQ25|T1FQ25_HELRO
Uncharacterized protein
Search

0.47	GO:0006470	protein dephosphorylation
0.38	GO:0034968	histone lysine methylation

0.49	GO:0004722	protein serine/threonine phosphatase activity
0.38	GO:0018024	histone-lysine N-methyltransferase activity
0.34	GO:0046872	metal ion binding

0.30

GO:0031224

intrinsic component of membrane

0.38

EC:2.1.1.43

GO:0018024

tr|T1FQ26|T1FQ26_HELRO
Uncharacterized protein
Search

tr|T1FQ27|T1FQ27_HELRO
Uncharacterized protein
Search

0.57	GO:0006334	nucleosome assembly
0.51	GO:0006357	regulation of transcription by RNA polymerase II
0.47	GO:0032784	regulation of DNA-templated transcription, elongation
0.46	GO:0006265	DNA topological change
0.46	GO:0045893	positive regulation of transcription, DNA-templated
0.41	GO:0007165	signal transduction
0.40	GO:0006351	transcription, DNA-templated

0.51	GO:0000991	transcription factor activity, core RNA polymerase II binding
0.48	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.48	GO:0000987	proximal promoter sequence-specific DNA binding
0.48	GO:0003917	DNA topoisomerase type I activity
0.44	GO:0046983	protein dimerization activity
0.43	GO:0016874	ligase activity
0.43	GO:0004871	signal transducer activity

0.54	GO:0005634	nucleus
0.49	GO:0017053	transcriptional repressor complex
0.45	GO:0005694	chromosome

0.48

EC:5.99.1.2

GO:0003917

tr|T1FQ28|T1FQ28_HELRO
Uncharacterized protein
Search

0.55	Multiple coagulation factor deficiency protein 2

0.40

GO:0032504

multicellular organism reproduction

0.67	GO:0005509	calcium ion binding
0.33	GO:0016853	isomerase activity
0.32	GO:0003676	nucleic acid binding

0.35	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:5

GO:0016853

tr|T1FQ29|T1FQ29_HELRO
Uncharacterized protein
Search

UFD1L

0.83	Ubiquitin recognition factor in ER-associated degradation protein 1

0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.51	GO:0039536	negative regulation of RIG-I signaling pathway
0.51	GO:0032480	negative regulation of type I interferon production
0.50	GO:0071712	ER-associated misfolded protein catabolic process
0.50	GO:1903513	endoplasmic reticulum to cytosol transport
0.50	GO:0032527	protein exit from endoplasmic reticulum
0.42	GO:0071466	cellular response to xenobiotic stimulus
0.35	GO:0070987	error-free translesion synthesis
0.34	GO:0001501	skeletal system development
0.34	GO:0016579	protein deubiquitination

0.51	GO:0036435	K48-linked polyubiquitin modification-dependent protein binding
0.38	GO:0051117	ATPase binding
0.37	GO:0032403	protein complex binding
0.36	GO:0005102	receptor binding
0.34	GO:0004843	thiol-dependent ubiquitin-specific protease activity

0.53	GO:0036501	UFD1-NPL4 complex
0.51	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex
0.35	GO:0005829	cytosol
0.34	GO:0005634	nucleus
0.33	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

tr|T1FQ30|T1FQ30_HELRO
Uncharacterized protein
Search

0.75	T-box transcription factor TBX1 (inferred by orthology to a zebrafish protein)

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.48	GO:0014043	negative regulation of neuron maturation
0.47	GO:0001756	somitogenesis
0.47	GO:0007498	mesoderm development
0.47	GO:0007369	gastrulation
0.46	GO:0001708	cell fate specification
0.46	GO:0000578	embryonic axis specification

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.46	GO:0001102	RNA polymerase II activating transcription factor binding
0.46	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.45	GO:0001067	regulatory region nucleic acid binding

0.61	GO:0005634	nucleus
0.34	GO:0005667	transcription factor complex
0.30	GO:0044425	membrane part

tr|T1FQ31|T1FQ31_HELRO
Tetraspanin
Search

0.47	Tetraspanin

0.30

GO:0044425

membrane part

tr|T1FQ32|T1FQ32_HELRO
Uncharacterized protein
Search

TXNRD2

0.36	FAD dependent oxidoreductase

0.68	GO:0045454	cell redox homeostasis
0.68	GO:0098869	cellular oxidant detoxification
0.58	GO:0022900	electron transport chain
0.40	GO:0000305	response to oxygen radical
0.36	GO:0008340	determination of adult lifespan
0.36	GO:0001666	response to hypoxia

0.77	GO:0004791	thioredoxin-disulfide reductase activity
0.66	GO:0050660	flavin adenine dinucleotide binding
0.59	GO:0009055	electron transfer activity
0.38	GO:0015035	protein disulfide oxidoreductase activity
0.38	GO:0004362	glutathione-disulfide reductase activity
0.35	GO:0042803	protein homodimerization activity

0.40	GO:0005739	mitochondrion
0.38	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.77	EC:1.8.1.9	GO:0004791
0.77	KEGG:R02016	GO:0004791

tr|T1FQ33|T1FQ33_HELRO
Uncharacterized protein
Search

0.68	GO:0007018	microtubule-based movement
0.43	GO:0070650	actin filament bundle distribution
0.43	GO:0021555	midbrain-hindbrain boundary morphogenesis
0.40	GO:0007605	sensory perception of sound
0.38	GO:0008360	regulation of cell shape
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:0010468	regulation of gene expression
0.34	GO:0007165	signal transduction
0.34	GO:0016192	vesicle-mediated transport

0.71	GO:0003779	actin binding
0.70	GO:0003774	motor activity
0.69	GO:0008017	microtubule binding
0.65	GO:0032403	protein complex binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0016758	transferase activity, transferring hexosyl groups
0.36	GO:0003700	DNA binding transcription factor activity
0.35	GO:0004386	helicase activity

0.74	GO:0016459	myosin complex
0.34	GO:0017053	transcriptional repressor complex
0.34	GO:0005874	microtubule
0.30	GO:0031224	intrinsic component of membrane

0.44

GO:0016758

tr|T1FQ34|T1FQ34_HELRO
Uncharacterized protein
Search

0.60	GO:0072583	clathrin-dependent endocytosis
0.51	GO:0048260	positive regulation of receptor-mediated endocytosis
0.50	GO:0097320	plasma membrane tubulation
0.45	GO:0015031	protein transport
0.41	GO:2000507	positive regulation of energy homeostasis
0.41	GO:2000253	positive regulation of feeding behavior
0.41	GO:0002021	response to dietary excess
0.37	GO:0035556	intracellular signal transduction
0.34	GO:0042594	response to starvation

0.48	GO:0017124	SH3 domain binding
0.47	GO:0005543	phospholipid binding
0.46	GO:0008017	microtubule binding

0.51	GO:0030122	AP-2 adaptor complex
0.34	GO:0043195	terminal bouton
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|T1FQ35|T1FQ35_HELRO
Uncharacterized protein
Search

tr|T1FQ36|T1FQ36_HELRO
Uncharacterized protein
Search

0.69	GO:0030163	protein catabolic process
0.53	GO:0033522	histone H2A ubiquitination
0.53	GO:0071233	cellular response to leucine
0.50	GO:0010529	negative regulation of transposition
0.50	GO:0007141	male meiosis I
0.50	GO:0006342	chromatin silencing
0.50	GO:0032007	negative regulation of TOR signaling
0.48	GO:0007131	reciprocal meiotic recombination
0.48	GO:0043632	modification-dependent macromolecule catabolic process
0.47	GO:0007283	spermatogenesis

0.61	GO:0008270	zinc ion binding
0.53	GO:0070728	leucine binding
0.52	GO:0016874	ligase activity
0.49	GO:0061630	ubiquitin protein ligase activity
0.33	GO:0005515	protein binding
0.32	GO:0008233	peptidase activity

0.49	GO:0000151	ubiquitin ligase complex
0.45	GO:0000785	chromatin
0.35	GO:0005737	cytoplasm
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.52

GO:0016874

tr|T1FQ37|T1FQ37_HELRO
Succinyl-CoA:3-ketoacid-coenzyme A transferase
Search

0.72	Succinyl-CoA:3-ketoacid-coenzyme A transferase

0.81	GO:0046952	ketone body catabolic process
0.36	GO:0042182	ketone catabolic process
0.35	GO:0016579	protein deubiquitination
0.35	GO:0014823	response to activity
0.35	GO:0060612	adipose tissue development
0.35	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus
0.35	GO:0045471	response to ethanol
0.35	GO:0006511	ubiquitin-dependent protein catabolic process
0.34	GO:0007584	response to nutrient
0.34	GO:0007507	heart development

0.80	GO:0008260	3-oxoacid CoA-transferase activity
0.35	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.34	GO:0042803	protein homodimerization activity
0.34	GO:0008235	metalloexopeptidase activity
0.34	GO:0008775	acetate CoA-transferase activity
0.33	GO:0030145	manganese ion binding
0.33	GO:0004177	aminopeptidase activity
0.33	GO:0003735	structural constituent of ribosome
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding

0.58	GO:0005739	mitochondrion
0.35	GO:0005654	nucleoplasm
0.33	GO:0005840	ribosome

0.80

EC:2.8.3.5

GO:0008260

tr|T1FQ38|T1FQ38_HELRO
Uncharacterized protein
Search

0.60	GO:0006508	proteolysis
0.32	GO:0000160	phosphorelay signal transduction system

0.81	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.39	GO:0020037	heme binding
0.34	GO:0001883	purine nucleoside binding
0.34	GO:0019001	guanyl nucleotide binding
0.34	GO:0032549	ribonucleoside binding
0.33	GO:0019706	protein-cysteine S-palmitoyltransferase activity
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0008270	zinc ion binding

0.45	GO:0005622	intracellular
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:2.3.1.225

GO:0019706

tr|T1FQ39|T1FQ39_HELRO
Uncharacterized protein
Search

tr|T1FQ40|T1FQ40_HELRO
Uncharacterized protein
Search

0.13	Kelch-like protein 8

0.72	GO:0016567	protein ubiquitination
0.57	GO:0006511	ubiquitin-dependent protein catabolic process

0.48

GO:0004842

ubiquitin-protein transferase activity

0.82	GO:0031463	Cul3-RING ubiquitin ligase complex
0.54	GO:0005654	nucleoplasm
0.42	GO:0014069	postsynaptic density
0.42	GO:0043025	neuronal cell body
0.41	GO:0043005	neuron projection
0.40	GO:0030054	cell junction

0.48

GO:0004842

tr|T1FQ41|T1FQ41_HELRO
Uncharacterized protein
Search

0.10	Nucleolin protein nsr1

0.40	GO:0022613	ribonucleoprotein complex biogenesis
0.40	GO:0031047	gene silencing by RNA
0.39	GO:0071826	ribonucleoprotein complex subunit organization
0.39	GO:0002183	cytoplasmic translational initiation
0.39	GO:0006446	regulation of translational initiation
0.39	GO:0000412	histone peptidyl-prolyl isomerization
0.39	GO:0034622	cellular macromolecular complex assembly
0.38	GO:0006396	RNA processing
0.38	GO:0016072	rRNA metabolic process
0.37	GO:0001522	pseudouridine synthesis

0.55	GO:0003723	RNA binding
0.40	GO:0008139	nuclear localization sequence binding
0.39	GO:0043047	single-stranded telomeric DNA binding
0.39	GO:0005528	FK506 binding
0.39	GO:0031369	translation initiation factor binding
0.37	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.36	GO:0004386	helicase activity
0.35	GO:0140098	catalytic activity, acting on RNA
0.35	GO:0030554	adenyl nucleotide binding
0.35	GO:0008186	RNA-dependent ATPase activity

0.40	GO:0044428	nuclear part
0.40	GO:0005852	eukaryotic translation initiation factor 3 complex
0.40	GO:0016282	eukaryotic 43S preinitiation complex
0.39	GO:0033290	eukaryotic 48S preinitiation complex
0.39	GO:0072588	box H/ACA RNP complex
0.39	GO:0070013	intracellular organelle lumen
0.37	GO:0012505	endomembrane system
0.37	GO:0043232	intracellular non-membrane-bounded organelle
0.36	GO:0019013	viral nucleocapsid
0.36	GO:0031967	organelle envelope

0.37

EC:5.2.1.8

GO:0003755

tr|T1FQ42|T1FQ42_HELRO
Uncharacterized protein
Search

tr|T1FQ43|T1FQ43_HELRO
Uncharacterized protein
Search

tr|T1FQ44|T1FQ44_HELRO
Uncharacterized protein
Search

tr|T1FQ45|T1FQ45_HELRO
Uncharacterized protein
Search

0.76	GO:0080009	mRNA methylation
0.41	GO:0008380	RNA splicing
0.40	GO:0006397	mRNA processing
0.40	GO:0010951	negative regulation of endopeptidase activity
0.34	GO:0055114	oxidation-reduction process

0.40	GO:0004866	endopeptidase inhibitor activity
0.37	GO:0003723	RNA binding
0.35	GO:0008270	zinc ion binding
0.34	GO:0016491	oxidoreductase activity

0.84	GO:0036396	RNA N6-methyladenosine methyltransferase complex
0.76	GO:0016607	nuclear speck
0.65	GO:0005829	cytosol
0.39	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0016491

tr|T1FQ46|T1FQ46_HELRO
Uncharacterized protein
Search

ZFYVE21

0.73	Zinc finger, FYVE domain containing 21

0.39	GO:0000724	double-strand break repair via homologous recombination
0.38	GO:0000910	cytokinesis
0.37	GO:1904669	ATP export
0.37	GO:1903319	positive regulation of protein maturation
0.37	GO:0045053	protein retention in Golgi apparatus
0.37	GO:0006623	protein targeting to vacuole
0.37	GO:0045324	late endosome to vacuole transport
0.36	GO:0071985	multivesicular body sorting pathway
0.35	GO:0009306	protein secretion
0.34	GO:0035023	regulation of Rho protein signal transduction

0.54	GO:0046872	metal ion binding
0.42	GO:0032266	phosphatidylinositol-3-phosphate binding
0.36	GO:0043130	ubiquitin binding
0.36	GO:0019904	protein domain specific binding
0.36	GO:0046982	protein heterodimerization activity
0.34	GO:0016307	phosphatidylinositol phosphate kinase activity
0.34	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.38	GO:0044440	endosomal part
0.35	GO:0098805	whole membrane
0.35	GO:0098588	bounding membrane of organelle
0.34	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.34

GO:0016307

tr|T1FQ47|T1FQ47_HELRO
Uncharacterized protein
Search

tr|T1FQ48|T1FQ48_HELRO
Uncharacterized protein
Search

tr|T1FQ49|T1FQ49_HELRO
Uncharacterized protein
Search

0.56	GO:0006811	ion transport
0.55	GO:0055085	transmembrane transport
0.47	GO:1901571	fatty acid derivative transport
0.45	GO:0006869	lipid transport
0.43	GO:0015849	organic acid transport
0.33	GO:0015850	organic hydroxy compound transport
0.33	GO:0007588	excretion
0.32	GO:0006351	transcription, DNA-templated
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.56	GO:0005215	transporter activity
0.33	GO:0003700	DNA binding transcription factor activity
0.32	GO:0030246	carbohydrate binding
0.32	GO:0003677	DNA binding

0.53	GO:0005886	plasma membrane
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

tr|T1FQ50|T1FQ50_HELRO
Uncharacterized protein
Search

0.39	Collagen triple helix repeat

0.35

GO:0005975

carbohydrate metabolic process

0.60	GO:0005509	calcium ion binding
0.57	GO:0005201	extracellular matrix structural constituent
0.37	GO:0030246	carbohydrate binding
0.36	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.74	GO:0005581	collagen trimer
0.36	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.36

GO:0004553

tr|T1FQ51|T1FQ51_HELRO
Uncharacterized protein
Search

0.40	Collagen triple helix repeat-containing protein (Fragment)

0.39	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.38	GO:0071230	cellular response to amino acid stimulus
0.38	GO:0030198	extracellular matrix organization
0.37	GO:0006338	chromatin remodeling
0.36	GO:0009405	pathogenesis
0.36	GO:0005975	carbohydrate metabolic process
0.35	GO:1903506	regulation of nucleic acid-templated transcription
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression
0.35	GO:0015074	DNA integration

0.60	GO:0005201	extracellular matrix structural constituent
0.48	GO:0005509	calcium ion binding
0.41	GO:0030246	carbohydrate binding
0.37	GO:0042393	histone binding
0.37	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.35	GO:0004386	helicase activity
0.35	GO:0016887	ATPase activity
0.35	GO:0003677	DNA binding
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0097367	carbohydrate derivative binding

0.64	GO:0005581	collagen trimer
0.57	GO:0005604	basement membrane
0.39	GO:0098645	collagen network
0.38	GO:0016514	SWI/SNF complex
0.35	GO:0019867	outer membrane
0.33	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane

0.37	EC:3.2.1	GO:0004553
0.34	KEGG:R03532	GO:0004601

tr|T1FQ52|T1FQ52_HELRO
Uncharacterized protein
Search

0.54	GO:0007165	signal transduction
0.51	GO:0016567	protein ubiquitination
0.43	GO:0034220	ion transmembrane transport
0.41	GO:0043065	positive regulation of apoptotic process
0.40	GO:0006816	calcium ion transport
0.39	GO:0198738	cell-cell signaling by wnt
0.37	GO:0006508	proteolysis
0.36	GO:0006471	protein ADP-ribosylation
0.36	GO:0006915	apoptotic process
0.35	GO:0071804	cellular potassium ion transport

0.47	GO:0005216	ion channel activity
0.40	GO:0017147	Wnt-protein binding
0.40	GO:0015085	calcium ion transmembrane transporter activity
0.38	GO:0070001	aspartic-type peptidase activity
0.38	GO:0043531	ADP binding
0.37	GO:0004175	endopeptidase activity
0.36	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.36	GO:0004842	ubiquitin-protein transferase activity
0.36	GO:0008080	N-acetyltransferase activity
0.36	GO:0022832	voltage-gated channel activity

0.43	GO:0031436	BRCA1-BARD1 complex
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.36	EC:2.4.2.30	GO:0003950
0.36	KEGG:R03876	GO:0004842

tr|T1FQ53|T1FQ53_HELRO
Uncharacterized protein
Search

tr|T1FQ54|T1FQ54_HELRO
Uncharacterized protein
Search

0.79

GO:0006334

nucleosome assembly

0.55

GO:0003677

DNA binding

0.74

GO:0000786

nucleosome

tr|T1FQ55|T1FQ55_HELRO
Uncharacterized protein
Search

tr|T1FQ56|T1FQ56_HELRO
Uncharacterized protein
Search

tr|T1FQ57|T1FQ57_HELRO
Uncharacterized protein
Search

tr|T1FQ58|T1FQ58_HELRO
Uncharacterized protein
Search

tr|T1FQ59|T1FQ59_HELRO
Uncharacterized protein
Search

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.39	GO:0007163	establishment or maintenance of cell polarity
0.39	GO:0001736	establishment of planar polarity
0.39	GO:0007424	open tracheal system development
0.39	GO:0048513	animal organ development
0.39	GO:0031346	positive regulation of cell projection organization
0.38	GO:0120035	regulation of plasma membrane bounded cell projection organization
0.38	GO:0060269	centripetally migrating follicle cell migration
0.38	GO:1902463	protein localization to cell leading edge
0.38	GO:0007295	growth of a germarium-derived egg chamber

0.70	GO:0005509	calcium ion binding
0.37	GO:0004930	G-protein coupled receptor activity
0.36	GO:0050839	cell adhesion molecule binding
0.36	GO:0032403	protein complex binding
0.35	GO:0005057	signal transducer activity, downstream of receptor
0.33	GO:0008237	metallopeptidase activity

0.56	GO:0005886	plasma membrane
0.39	GO:0030054	cell junction
0.38	GO:0098858	actin-based cell projection
0.38	GO:0031254	cell trailing edge
0.37	GO:0045178	basal part of cell
0.35	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0030027	lamellipodium
0.34	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

tr|T1FQ60|T1FQ60_HELRO
Uncharacterized protein
Search

0.74	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1FQ61|T1FQ61_HELRO
Uncharacterized protein
Search

tr|T1FQ62|T1FQ62_HELRO
Uncharacterized protein
Search

0.42	GO:0060627	regulation of vesicle-mediated transport
0.41	GO:0061191	positive regulation of vacuole fusion, non-autophagic
0.40	GO:0007035	vacuolar acidification
0.40	GO:0042144	vacuole fusion, non-autophagic
0.40	GO:0016192	vesicle-mediated transport
0.40	GO:0033059	cellular pigmentation
0.39	GO:0051641	cellular localization
0.39	GO:0000011	vacuole inheritance
0.39	GO:0034727	piecemeal microautophagy of the nucleus
0.38	GO:0016236	macroautophagy

0.66	GO:0003924	GTPase activity
0.64	GO:0032550	purine ribonucleoside binding
0.64	GO:0019001	guanyl nucleotide binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0005509	calcium ion binding
0.35	GO:0042578	phosphoric ester hydrolase activity
0.35	GO:0003972	RNA ligase (ATP) activity
0.34	GO:0004620	phospholipase activity
0.34	GO:0008168	methyltransferase activity

0.42	GO:0012505	endomembrane system
0.40	GO:0031982	vesicle
0.39	GO:1990816	vacuole-mitochondrion membrane contact site
0.39	GO:0098588	bounding membrane of organelle
0.39	GO:0000324	fungal-type vacuole
0.39	GO:0098805	whole membrane
0.38	GO:0044437	vacuolar part
0.37	GO:0005829	cytosol
0.36	GO:0031984	organelle subcompartment
0.36	GO:0098796	membrane protein complex

0.35	EC:3.1	GO:0042578
0.33	KEGG:R03876	GO:0004842

tr|T1FQ63|T1FQ63_HELRO
Uncharacterized protein
Search

tr|T1FQ64|T1FQ64_HELRO
Uncharacterized protein
Search

tr|T1FQ65|T1FQ65_HELRO
Uncharacterized protein
Search

0.70	GO:0006397	mRNA processing
0.43	GO:0006285	base-excision repair, AP site formation
0.33	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile

0.50	GO:0003676	nucleic acid binding
0.43	GO:0000703	oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity
0.41	GO:0140080	class III/IV DNA-(apurinic or apyrimidinic site) lyase activity
0.41	GO:0140078	class I DNA-(apurinic or apyrimidinic site) lyase activity
0.37	GO:0051539	4 iron, 4 sulfur cluster binding
0.35	GO:0046872	metal ion binding

0.38	GO:0005634	nucleus
0.37	GO:0005739	mitochondrion
0.34	GO:1902494	catalytic complex
0.34	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0044446	intracellular organelle part
0.32	GO:0005829	cytosol
0.30	GO:0016020	membrane

tr|T1FQ66|T1FQ66_HELRO
Uncharacterized protein
Search

0.58	GO:0006397	mRNA processing
0.46	GO:0006464	cellular protein modification process
0.44	GO:0008380	RNA splicing
0.42	GO:0016310	phosphorylation
0.41	GO:0007219	Notch signaling pathway
0.39	GO:0045892	negative regulation of transcription, DNA-templated
0.38	GO:0043484	regulation of RNA splicing
0.37	GO:0016569	covalent chromatin modification
0.37	GO:0006886	intracellular protein transport
0.37	GO:0061025	membrane fusion

0.45	GO:0004672	protein kinase activity
0.44	GO:0003676	nucleic acid binding
0.42	GO:0004842	ubiquitin-protein transferase activity
0.41	GO:0030554	adenyl nucleotide binding
0.40	GO:0032555	purine ribonucleotide binding
0.40	GO:0008144	drug binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0003682	chromatin binding
0.39	GO:0008270	zinc ion binding
0.39	GO:0005484	SNAP receptor activity

0.43	GO:0005634	nucleus
0.38	GO:0044446	intracellular organelle part
0.38	GO:0031974	membrane-enclosed lumen
0.38	GO:0034708	methyltransferase complex
0.36	GO:0043234	protein complex
0.36	GO:0030529	intracellular ribonucleoprotein complex
0.36	GO:0019013	viral nucleocapsid
0.36	GO:0005829	cytosol
0.34	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

0.37	EC:3.1.3.16	GO:0004721
0.42	KEGG:R03876	GO:0004842

tr|T1FQ67|T1FQ67_HELRO
Uncharacterized protein
Search

tr|T1FQ68|T1FQ68_HELRO
Uncharacterized protein
Search

tr|T1FQ69|T1FQ69_HELRO
Coatomer subunit delta
Search

ARCN1

0.68	Coatomer subunit delta

0.80	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.64	GO:0015031	protein transport
0.53	GO:0021691	cerebellar Purkinje cell layer maturation
0.49	GO:0008344	adult locomotory behavior
0.49	GO:0043473	pigmentation
0.34	GO:0006891	intra-Golgi vesicle-mediated transport
0.34	GO:0006888	ER to Golgi vesicle-mediated transport
0.33	GO:0034613	cellular protein localization

0.33	GO:0003723	RNA binding
0.33	GO:0005515	protein binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.80	GO:0030126	COPI vesicle coat
0.72	GO:0000139	Golgi membrane
0.44	GO:0005783	endoplasmic reticulum
0.34	GO:0030133	transport vesicle
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0005829	cytosol

tr|T1FQ70|T1FQ70_HELRO
Elongation of very long chain fatty acids protein
Search

0.35	Elongation of very long chain fatty acids protein

0.70	GO:0006633	fatty acid biosynthetic process
0.64	GO:0000038	very long-chain fatty acid metabolic process
0.60	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process
0.59	GO:0033559	unsaturated fatty acid metabolic process
0.43	GO:0030148	sphingolipid biosynthetic process
0.36	GO:0048794	swim bladder development
0.31	GO:0055114	oxidation-reduction process

0.82	GO:0102756	very-long-chain 3-ketoacyl-CoA synthase activity
0.82	GO:0102338	3-oxo-lignoceronyl-CoA synthase activity
0.82	GO:0102336	3-oxo-arachidoyl-CoA synthase activity
0.82	GO:0102337	3-oxo-cerotoyl-CoA synthase activity
0.66	GO:0009922	fatty acid elongase activity
0.31	GO:0016491	oxidoreductase activity

0.55	GO:0005783	endoplasmic reticulum
0.54	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.52	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.82

EC:2.3.1.199

GO:0102338

tr|T1FQ71|T1FQ71_HELRO
Uncharacterized protein
Search

SMARCE1

0.83	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member

0.77	GO:0043044	ATP-dependent chromatin remodeling
0.37	GO:0031498	chromatin disassembly
0.37	GO:0032986	protein-DNA complex disassembly
0.36	GO:0034728	nucleosome organization
0.35	GO:0022008	neurogenesis
0.35	GO:0045892	negative regulation of transcription, DNA-templated

0.53	GO:0003677	DNA binding
0.37	GO:0016922	ligand-dependent nuclear receptor binding
0.37	GO:0047485	protein N-terminus binding
0.35	GO:0008080	N-acetyltransferase activity
0.34	GO:0003723	RNA binding

0.78	GO:0016514	SWI/SNF complex
0.36	GO:0071565	nBAF complex
0.36	GO:0071564	npBAF complex
0.36	GO:0017053	transcriptional repressor complex
0.36	GO:0005654	nucleoplasm

0.35

GO:0008080

tr|T1FQ72|T1FQ72_HELRO
Uncharacterized protein
Search

0.10	solute carrier family 45 member 3-like

0.58	GO:0015770	sucrose transport
0.51	GO:0045723	positive regulation of fatty acid biosynthetic process
0.51	GO:0048713	regulation of oligodendrocyte differentiation
0.50	GO:0010907	positive regulation of glucose metabolic process
0.49	GO:0055085	transmembrane transport
0.47	GO:0048066	developmental pigmentation
0.42	GO:0042948	salicin transport
0.40	GO:0009846	pollen germination
0.39	GO:0015768	maltose transport
0.38	GO:0009416	response to light stimulus

0.59	GO:0008506	sucrose:proton symporter activity
0.42	GO:0015573	beta-glucoside transmembrane transporter activity
0.41	GO:0005364	maltose:proton symporter activity
0.40	GO:0015665	alcohol transmembrane transporter activity
0.37	GO:0015238	drug transmembrane transporter activity
0.35	GO:0008083	growth factor activity

0.38	GO:0005887	integral component of plasma membrane
0.34	GO:0033162	melanosome membrane

tr|T1FQ73|T1FQ73_HELRO
Tetraspanin
Search

0.40	Tetraspanin

0.30

GO:0044425

membrane part

tr|T1FQ74|T1FQ74_HELRO
Uncharacterized protein
Search

0.54	GO:0007219	Notch signaling pathway
0.49	GO:0045967	negative regulation of growth rate
0.49	GO:0030154	cell differentiation
0.48	GO:0007275	multicellular organism development
0.47	GO:2000974	negative regulation of pro-B cell differentiation
0.47	GO:1903849	positive regulation of aorta morphogenesis
0.47	GO:2001027	negative regulation of endothelial cell chemotaxis
0.47	GO:0002085	inhibition of neuroepithelial cell differentiation
0.47	GO:0072602	interleukin-4 secretion
0.47	GO:0061419	positive regulation of transcription from RNA polymerase II promoter in response to hypoxia

0.69	GO:0005509	calcium ion binding
0.47	GO:0004872	receptor activity
0.47	GO:0005112	Notch binding
0.45	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.45	GO:0031490	chromatin DNA binding
0.44	GO:0001047	core promoter binding
0.42	GO:0004857	enzyme inhibitor activity
0.42	GO:0046982	protein heterodimerization activity
0.41	GO:0019899	enzyme binding
0.39	GO:0043565	sequence-specific DNA binding

0.47	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex
0.44	GO:0043235	receptor complex
0.44	GO:0016324	apical plasma membrane
0.43	GO:0009986	cell surface
0.43	GO:0005912	adherens junction
0.42	GO:0031410	cytoplasmic vesicle
0.41	GO:0005783	endoplasmic reticulum
0.39	GO:0005634	nucleus
0.38	GO:0005576	extracellular region
0.37	GO:0005581	collagen trimer

0.39

GO:0004674

tr|T1FQ75|T1FQ75_HELRO
Uncharacterized protein
Search

0.78	GO:0060285	cilium-dependent cell motility
0.75	GO:0070286	axonemal dynein complex assembly
0.67	GO:0007368	determination of left/right symmetry
0.64	GO:0007507	heart development
0.45	GO:0006397	mRNA processing
0.39	GO:0007018	microtubule-based movement
0.38	GO:0006508	proteolysis
0.35	GO:0008654	phospholipid biosynthetic process

0.40	GO:0004222	metalloendopeptidase activity
0.40	GO:0003777	microtubule motor activity
0.40	GO:0008017	microtubule binding
0.37	GO:0046872	metal ion binding
0.36	GO:0016780	phosphotransferase activity, for other substituted phosphate groups
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0003676	nucleic acid binding

0.53	GO:0005930	axoneme
0.36	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.40

GO:0004222

tr|T1FQ76|T1FQ76_HELRO
Uncharacterized protein
Search

tr|T1FQ77|T1FQ77_HELRO
Uncharacterized protein
Search

0.42

GO:0016567

protein ubiquitination

0.42

GO:0004842

ubiquitin-protein transferase activity

0.42	GO:0020005	symbiont-containing vacuole membrane
0.42	GO:0020036	Maurer's cleft
0.37	GO:0033644	host cell membrane
0.30	GO:0031224	intrinsic component of membrane

0.42

GO:0004842

tr|T1FQ78|T1FQ78_HELRO
Uncharacterized protein
Search

DNAH7

0.63	Dynein heavy chain

0.74	GO:0007018	microtubule-based movement
0.59	GO:0036159	inner dynein arm assembly
0.44	GO:0071910	determination of liver left/right asymmetry
0.38	GO:0060285	cilium-dependent cell motility
0.35	GO:0006468	protein phosphorylation

0.75	GO:0003777	microtubule motor activity
0.55	GO:0005509	calcium ion binding
0.55	GO:0045503	dynein light chain binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.55	GO:0051959	dynein light intermediate chain binding
0.54	GO:0045505	dynein intermediate chain binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0016887	ATPase activity
0.35	GO:0004672	protein kinase activity

0.78	GO:0030286	dynein complex
0.57	GO:0044447	axoneme part
0.46	GO:0005829	cytosol
0.39	GO:0005874	microtubule
0.30	GO:0016021	integral component of membrane

0.47

GO:0016887

tr|T1FQ79|T1FQ79_HELRO
Uncharacterized protein
Search

0.66	GO:0031848	protection from non-homologous end joining at telomere
0.62	GO:0031860	telomeric 3' overhang formation
0.62	GO:0036297	interstrand cross-link repair
0.62	GO:0031627	telomeric loop formation
0.59	GO:0010833	telomere maintenance via telomere lengthening
0.58	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.55	GO:0000075	cell cycle checkpoint
0.53	GO:0006303	double-strand break repair via nonhomologous end joining
0.37	GO:0006468	protein phosphorylation
0.36	GO:0007216	G-protein coupled glutamate receptor signaling pathway

0.62	GO:0004527	exonuclease activity
0.53	GO:0042803	protein homodimerization activity
0.50	GO:0044877	macromolecular complex binding
0.49	GO:0003684	damaged DNA binding
0.49	GO:0004536	deoxyribonuclease activity
0.37	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.37	GO:0016301	kinase activity
0.36	GO:0043047	single-stranded telomeric DNA binding
0.36	GO:0140096	catalytic activity, acting on a protein
0.36	GO:0030554	adenyl nucleotide binding

0.61	GO:0000784	nuclear chromosome, telomeric region
0.55	GO:0005813	centrosome
0.54	GO:0016604	nuclear body
0.34	GO:0005887	integral component of plasma membrane
0.34	GO:0005737	cytoplasm
0.34	GO:0070419	nonhomologous end joining complex
0.33	GO:0012505	endomembrane system

0.37

GO:0016773

tr|T1FQ80|T1FQ80_HELRO
Uncharacterized protein
Search

tr|T1FQ81|T1FQ81_HELRO
Uncharacterized protein
Search

CLIP3

0.82	CAP-Gly domain-containing linker protein 3

0.54	GO:0018231	peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine
0.54	GO:0031115	negative regulation of microtubule polymerization
0.54	GO:0072321	chaperone-mediated protein transport
0.53	GO:0010828	positive regulation of glucose transport
0.52	GO:1903078	positive regulation of protein localization to plasma membrane
0.52	GO:0018345	protein palmitoylation
0.52	GO:0045444	fat cell differentiation
0.51	GO:0045807	positive regulation of endocytosis
0.49	GO:0043065	positive regulation of apoptotic process
0.49	GO:0001934	positive regulation of protein phosphorylation

0.55	GO:0035594	ganglioside binding
0.48	GO:0008017	microtubule binding
0.39	GO:0070840	dynein complex binding
0.38	GO:0005085	guanyl-nucleotide exchange factor activity
0.37	GO:0005509	calcium ion binding
0.35	GO:0071889	14-3-3 protein binding
0.34	GO:0016491	oxidoreductase activity
0.34	GO:0019901	protein kinase binding
0.34	GO:0003777	microtubule motor activity
0.32	GO:0032559	adenyl ribonucleotide binding

0.53	GO:0043231	intracellular membrane-bounded organelle
0.52	GO:0055038	recycling endosome membrane
0.52	GO:0031901	early endosome membrane
0.50	GO:0045121	membrane raft
0.45	GO:0031984	organelle subcompartment
0.40	GO:0005886	plasma membrane
0.38	GO:0005869	dynactin complex
0.35	GO:1905369	endopeptidase complex
0.34	GO:0030424	axon
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0016491

tr|T1FQ82|T1FQ82_HELRO
Uncharacterized protein
Search

tr|T1FQ83|T1FQ83_HELRO
Uncharacterized protein
Search

tr|T1FQ84|T1FQ84_HELRO
Uncharacterized protein
Search

tr|T1FQ85|T1FQ85_HELRO
Uncharacterized protein
Search

tr|T1FQ86|T1FQ86_HELRO
Uncharacterized protein
Search

0.52

GO:0046872

metal ion binding

0.39	GO:0005794	Golgi apparatus
0.30	GO:0044425	membrane part

tr|T1FQ87|T1FQ87_HELRO
Uncharacterized protein
Search

tr|T1FQ88|T1FQ88_HELRO
Uncharacterized protein
Search

0.56	GO:0051568	histone H3-K4 methylation
0.41	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway
0.40	GO:0043627	response to estrogen
0.39	GO:0008284	positive regulation of cell proliferation
0.39	GO:0045944	positive regulation of transcription by RNA polymerase II
0.37	GO:0031497	chromatin assembly
0.37	GO:0034728	nucleosome organization
0.36	GO:0065004	protein-DNA complex assembly
0.35	GO:0070647	protein modification by small protein conjugation or removal
0.35	GO:0006338	chromatin remodeling

0.57	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.51	GO:0046872	metal ion binding
0.39	GO:0044212	transcription regulatory region DNA binding
0.36	GO:0003723	RNA binding
0.35	GO:0043168	anion binding
0.35	GO:0017076	purine nucleotide binding
0.35	GO:0097367	carbohydrate derivative binding
0.35	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.35	GO:0008144	drug binding
0.35	GO:0070063	RNA polymerase binding

0.54	GO:0035097	histone methyltransferase complex
0.36	GO:0005730	nucleolus
0.36	GO:0000790	nuclear chromatin
0.34	GO:1904949	ATPase complex
0.34	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex
0.33	GO:0090568	nuclear transcriptional repressor complex
0.33	GO:0031430	M band
0.33	GO:0000118	histone deacetylase complex
0.33	GO:1905368	peptidase complex
0.33	GO:0005865	striated muscle thin filament

0.35	EC:2.7.7.6	GO:0003899
0.34	KEGG:R05202	GO:0035299

tr|T1FQ89|T1FQ89_HELRO
Uncharacterized protein
Search

MTMR2

0.97	Myotubularin-related protein 2

0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.48	GO:0046856	phosphatidylinositol dephosphorylation
0.46	GO:0031642	negative regulation of myelination
0.45	GO:0060304	regulation of phosphatidylinositol dephosphorylation
0.45	GO:0032288	myelin assembly
0.43	GO:0051262	protein tetramerization
0.43	GO:0046855	inositol phosphate dephosphorylation
0.42	GO:0048666	neuron development
0.40	GO:2000645	negative regulation of receptor catabolic process
0.39	GO:0097062	dendritic spine maintenance

0.74	GO:0004725	protein tyrosine phosphatase activity
0.50	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity
0.50	GO:0004438	phosphatidylinositol-3-phosphatase activity
0.41	GO:0042803	protein homodimerization activity
0.37	GO:0008138	protein tyrosine/serine/threonine phosphatase activity

0.46	GO:0031901	early endosome membrane
0.42	GO:0005829	cytosol
0.42	GO:0005774	vacuolar membrane
0.38	GO:0043197	dendritic spine
0.38	GO:0014069	postsynaptic density
0.38	GO:0005634	nucleus
0.38	GO:0008021	synaptic vesicle
0.38	GO:0070062	extracellular exosome
0.38	GO:0030424	axon
0.37	GO:0097060	synaptic membrane

0.74

GO:0004725

tr|T1FQ90|T1FQ90_HELRO
Uncharacterized protein
Search

tr|T1FQ91|T1FQ91_HELRO
Uncharacterized protein
Search

0.55	Insulin-like growth factor 2 mRNA-binding protein 3

0.34	GO:0051028	mRNA transport
0.34	GO:0006417	regulation of translation

0.70	GO:0003729	mRNA binding
0.33	GO:0005515	protein binding

0.46	GO:0005829	cytosol
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

tr|T1FQ92|T1FQ92_HELRO
Uncharacterized protein
Search

0.43	GO:0050982	detection of mechanical stimulus
0.42	GO:0070588	calcium ion transmembrane transport
0.39	GO:0003127	detection of nodal flow
0.38	GO:0070986	left/right axis specification
0.36	GO:0098609	cell-cell adhesion

0.67	GO:0005509	calcium ion binding
0.43	GO:0005262	calcium channel activity
0.35	GO:0005515	protein binding

0.40	GO:0097730	non-motile cilium
0.40	GO:0034704	calcium channel complex
0.37	GO:0060170	ciliary membrane

tr|T1FQ93|T1FQ93_HELRO
Uncharacterized protein
Search

tr|T1FQ94|T1FQ94_HELRO
Uncharacterized protein
Search

tr|T1FQ95|T1FQ95_HELRO
Uncharacterized protein
Search

COL23A1

0.41	Collagen type XXIII alpha 1 chain

0.44	GO:0033622	integrin activation
0.44	GO:0071230	cellular response to amino acid stimulus
0.44	GO:0051894	positive regulation of focal adhesion assembly
0.43	GO:0033627	cell adhesion mediated by integrin
0.43	GO:0010951	negative regulation of endopeptidase activity
0.41	GO:0035987	endodermal cell differentiation
0.37	GO:0030198	extracellular matrix organization
0.37	GO:0048513	animal organ development
0.37	GO:0072359	circulatory system development
0.36	GO:0035295	tube development

0.53	GO:0005201	extracellular matrix structural constituent
0.43	GO:0004867	serine-type endopeptidase inhibitor activity
0.43	GO:0005178	integrin binding
0.38	GO:0042802	identical protein binding
0.38	GO:0042302	structural constituent of cuticle
0.37	GO:0048407	platelet-derived growth factor binding
0.35	GO:0046332	SMAD binding
0.35	GO:0002020	protease binding
0.34	GO:0003697	single-stranded DNA binding
0.34	GO:0004715	non-membrane spanning protein tyrosine kinase activity

0.66	GO:0005581	collagen trimer
0.52	GO:0031012	extracellular matrix
0.36	GO:0099081	supramolecular polymer
0.35	GO:0005615	extracellular space
0.34	GO:0005788	endoplasmic reticulum lumen
0.34	GO:0044214	spanning component of plasma membrane
0.33	GO:0030056	hemidesmosome
0.33	GO:0031594	neuromuscular junction
0.33	GO:0005938	cell cortex
0.32	GO:0019867	outer membrane

0.34

EC:2.7.10.2

GO:0004715

tr|T1FQ96|T1FQ96_HELRO
Uncharacterized protein
Search

TBPL1

0.53	TATA-box binding protein like 1

0.69	GO:0006352	DNA-templated transcription, initiation
0.41	GO:0006366	transcription by RNA polymerase II
0.40	GO:0035209	pupal development
0.40	GO:0035277	spiracle morphogenesis, open tracheal system
0.40	GO:0035071	salivary gland cell autophagic cell death
0.40	GO:0060963	positive regulation of ribosomal protein gene transcription by RNA polymerase II
0.39	GO:0035075	response to ecdysone
0.39	GO:0009792	embryo development ending in birth or egg hatching
0.38	GO:0065004	protein-DNA complex assembly
0.35	GO:0006413	translational initiation

0.55	GO:0003677	DNA binding
0.39	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly
0.38	GO:0001067	regulatory region nucleic acid binding
0.38	GO:0003682	chromatin binding
0.36	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.35	GO:0003743	translation initiation factor activity
0.34	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.33	GO:0008270	zinc ion binding

0.40	GO:0001674	female germ cell nucleus
0.39	GO:0001673	male germ cell nucleus
0.39	GO:0005700	polytene chromosome
0.38	GO:0005669	transcription factor TFIID complex
0.32	GO:0005737	cytoplasm

0.36

EC:1.3.1.74

GO:0032440

tr|T1FQ97|T1FQ97_HELRO
Uncharacterized protein
Search

0.60	GO:0006508	proteolysis
0.34	GO:0097659	nucleic acid-templated transcription
0.34	GO:2001141	regulation of RNA biosynthetic process
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression
0.33	GO:0010467	gene expression
0.33	GO:0055114	oxidation-reduction process
0.33	GO:0034645	cellular macromolecule biosynthetic process

0.77	GO:0070003	threonine-type peptidase activity
0.64	GO:0004175	endopeptidase activity
0.37	GO:0008798	beta-aspartyl-peptidase activity
0.33	GO:0003677	DNA binding
0.33	GO:0016491	oxidoreductase activity

0.34

GO:0005634

nucleus

0.37

EC:3.4.19.5

GO:0008798

tr|T1FQ98|T1FQ98_HELRO
Uncharacterized protein
Search

0.66	GO:0043547	positive regulation of GTPase activity
0.64	GO:0010469	regulation of receptor activity
0.57	GO:0006897	endocytosis
0.41	GO:0018996	molting cycle, collagen and cuticulin-based cuticle
0.38	GO:0051036	regulation of endosome size
0.34	GO:0006915	apoptotic process
0.33	GO:0015031	protein transport
0.33	GO:0010976	positive regulation of neuron projection development
0.33	GO:0060271	cilium assembly
0.32	GO:0061025	membrane fusion

0.66	GO:0008083	growth factor activity
0.66	GO:0005096	GTPase activator activity
0.50	GO:0046872	metal ion binding
0.41	GO:0032794	GTPase activating protein binding
0.40	GO:0019904	protein domain specific binding
0.40	GO:0042803	protein homodimerization activity
0.37	GO:0017137	Rab GTPase binding
0.35	GO:0033925	mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity
0.32	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

0.56	GO:0005768	endosome
0.41	GO:0030139	endocytic vesicle
0.36	GO:0043234	protein complex
0.36	GO:0043231	intracellular membrane-bounded organelle
0.32	GO:0005615	extracellular space
0.32	GO:0044433	cytoplasmic vesicle part
0.32	GO:0098805	whole membrane
0.32	GO:0098588	bounding membrane of organelle
0.30	GO:0016021	integral component of membrane

0.35

EC:3.2.1.96

GO:0033925

tr|T1FQ99|T1FQ99_HELRO
Uncharacterized protein
Search

tr|T1FQA0|T1FQA0_HELRO
Uncharacterized protein
Search

0.42	GO:0010639	negative regulation of organelle organization
0.39	GO:1901880	negative regulation of protein depolymerization
0.39	GO:0030834	regulation of actin filament depolymerization
0.39	GO:0032272	negative regulation of protein polymerization
0.39	GO:1902904	negative regulation of supramolecular fiber organization
0.39	GO:0001522	pseudouridine synthesis
0.39	GO:0071173	spindle assembly checkpoint
0.39	GO:1902100	negative regulation of metaphase/anaphase transition of cell cycle
0.39	GO:1905819	negative regulation of chromosome separation
0.39	GO:0030833	regulation of actin filament polymerization

0.63	GO:0045735	nutrient reservoir activity
0.43	GO:0030156	benzodiazepine receptor binding
0.41	GO:0005509	calcium ion binding
0.39	GO:0016301	kinase activity
0.38	GO:0005487	structural constituent of nuclear pore
0.37	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.36	GO:0140096	catalytic activity, acting on a protein
0.36	GO:0016775	phosphotransferase activity, nitrogenous group as acceptor
0.36	GO:0004871	signal transducer activity
0.35	GO:0008270	zinc ion binding

0.40	GO:0030479	actin cortical patch
0.38	GO:0005643	nuclear pore
0.37	GO:1905369	endopeptidase complex
0.37	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.36

GO:0016775

tr|T1FQA1|T1FQA1_HELRO
Uncharacterized protein
Search

0.53	GO:0055114	oxidation-reduction process
0.51	GO:0006690	icosanoid metabolic process
0.50	GO:0098869	cellular oxidant detoxification
0.49	GO:1901570	fatty acid derivative biosynthetic process
0.48	GO:0002540	leukotriene production involved in inflammatory response
0.48	GO:0031408	oxylipin biosynthetic process
0.39	GO:0033559	unsaturated fatty acid metabolic process
0.39	GO:0001676	long-chain fatty acid metabolic process
0.37	GO:0051240	positive regulation of multicellular organismal process
0.37	GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway

0.75	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.56	GO:0005506	iron ion binding
0.54	GO:0004096	catalase activity
0.47	GO:0020037	heme binding
0.37	GO:0004464	leukotriene-C4 synthase activity
0.36	GO:0008391	arachidonic acid monooxygenase activity
0.35	GO:0005515	protein binding
0.35	GO:0016166	phytoene dehydrogenase activity
0.34	GO:0005509	calcium ion binding

0.51	GO:0005641	nuclear envelope lumen
0.49	GO:0016363	nuclear matrix
0.48	GO:0031965	nuclear membrane
0.44	GO:0005829	cytosol
0.44	GO:0005654	nucleoplasm
0.36	GO:0042383	sarcolemma
0.35	GO:0030425	dendrite
0.35	GO:0019898	extrinsic component of membrane
0.34	GO:0005615	extracellular space
0.34	GO:0005856	cytoskeleton

0.75	EC:1.13.11	GO:0016702
0.37	KEGG:R03059	GO:0004464

tr|T1FQA2|T1FQA2_HELRO
Uncharacterized protein
Search

UNKL

0.80	Putative E3 ubiquitin-protein ligase UNKL isoform B

0.57	GO:0016874	ligase activity
0.54	GO:0046872	metal ion binding

0.57

GO:0016874

tr|T1FQA3|T1FQA3_HELRO
Uncharacterized protein
Search

0.55	GO:0006811	ion transport
0.52	GO:0055085	transmembrane transport
0.47	GO:0006884	cell volume homeostasis
0.44	GO:0071477	cellular hypotonic salinity response
0.37	GO:0036211	protein modification process
0.37	GO:0007268	chemical synaptic transmission
0.36	GO:0044267	cellular protein metabolic process
0.36	GO:0016310	phosphorylation
0.35	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA
0.35	GO:0043085	positive regulation of catalytic activity

0.53	GO:0015379	potassium:chloride symporter activity
0.39	GO:0022820	potassium ion symporter activity
0.37	GO:0004672	protein kinase activity
0.35	GO:0030554	adenyl nucleotide binding
0.35	GO:0097367	carbohydrate derivative binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0008270	zinc ion binding
0.34	GO:0008420	CTD phosphatase activity
0.34	GO:0008047	enzyme activator activity

0.44	GO:0005887	integral component of plasma membrane
0.35	GO:0005634	nucleus
0.34	GO:1990234	transferase complex
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0071561	nucleus-vacuole junction
0.33	GO:0044446	intracellular organelle part
0.33	GO:0031410	cytoplasmic vesicle
0.33	GO:0043234	protein complex
0.33	GO:0012505	endomembrane system
0.33	GO:0012506	vesicle membrane

0.33	EC:3.1.3.2	GO:0003993
0.33	KEGG:R03876	GO:0004842

tr|T1FQA4|T1FQA4_HELRO
Uncharacterized protein
Search

tr|T1FQA5|T1FQA5_HELRO
Uncharacterized protein
Search

COG5

0.83	Oligomeric Golgi complex subunit

0.81	GO:0006891	intra-Golgi vesicle-mediated transport
0.34	GO:0015031	protein transport
0.34	GO:0006888	ER to Golgi vesicle-mediated transport

0.33

GO:0005515

protein binding

0.80	GO:0017119	Golgi transport complex
0.48	GO:0005654	nucleoplasm
0.35	GO:0000139	Golgi membrane
0.35	GO:0005829	cytosol
0.34	GO:0005802	trans-Golgi network

tr|T1FQA6|T1FQA6_HELRO
Uncharacterized protein
Search

0.10	Neural proliferation differentiation and control protein 1

0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression
0.32	GO:0097659	nucleic acid-templated transcription
0.32	GO:0010467	gene expression
0.32	GO:0034645	cellular macromolecule biosynthetic process
0.32	GO:0055114	oxidation-reduction process

0.34	GO:0003700	DNA binding transcription factor activity
0.33	GO:0003677	DNA binding
0.33	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.33	GO:0005515	protein binding
0.33	GO:0020037	heme binding
0.33	GO:0005506	iron ion binding

0.34	GO:0005634	nucleus
0.30	GO:0044425	membrane part

0.33

EC:1.14

GO:0016705

tr|T1FQA7|T1FQA7_HELRO
Uncharacterized protein
Search

tr|T1FQA8|T1FQA8_HELRO
Uncharacterized protein
Search

0.30

GO:0044425

membrane part

tr|T1FQA9|T1FQA9_HELRO
Uncharacterized protein
Search

0.41	GO:0006270	DNA replication initiation
0.38	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA
0.38	GO:0016570	histone modification
0.37	GO:0006355	regulation of transcription, DNA-templated
0.37	GO:0043085	positive regulation of catalytic activity
0.37	GO:0018022	peptidyl-lysine methylation
0.36	GO:0006351	transcription, DNA-templated
0.36	GO:0031156	regulation of sorocarp development
0.36	GO:0007018	microtubule-based movement
0.36	GO:0020033	antigenic variation

0.42	GO:0046872	metal ion binding
0.42	GO:0003723	RNA binding
0.38	GO:0003677	DNA binding
0.38	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0017111	nucleoside-triphosphatase activity
0.37	GO:0008047	enzyme activator activity
0.37	GO:0003700	DNA binding transcription factor activity
0.37	GO:0018024	histone-lysine N-methyltransferase activity

0.40	GO:0005634	nucleus
0.35	GO:0098794	postsynapse
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.37	EC:3.6.1.15	GO:0017111
0.35	KEGG:R03876	GO:0004842

tr|T1FQB0|T1FQB0_HELRO
Uncharacterized protein
Search

0.67	GO:0006886	intracellular protein transport
0.54	GO:0035281	pre-miRNA export from nucleus
0.54	GO:1900370	positive regulation of RNA interference
0.53	GO:0006611	protein export from nucleus
0.46	GO:0046825	regulation of protein export from nucleus
0.35	GO:0006360	transcription by RNA polymerase I
0.35	GO:0006383	transcription by RNA polymerase III

0.77	GO:0008536	Ran GTPase binding
0.50	GO:0070883	pre-miRNA binding
0.47	GO:0003729	mRNA binding
0.46	GO:0005049	nuclear export signal receptor activity
0.45	GO:0008565	protein transporter activity
0.44	GO:0000049	tRNA binding
0.36	GO:0001054	RNA polymerase I activity
0.35	GO:0001056	RNA polymerase III activity

0.61	GO:0005634	nucleus
0.55	GO:0042565	RNA nuclear export complex
0.52	GO:0035068	micro-ribonucleoprotein complex
0.44	GO:0005829	cytosol
0.44	GO:0031974	membrane-enclosed lumen
0.40	GO:0044446	intracellular organelle part
0.35	GO:0000428	DNA-directed RNA polymerase complex
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

tr|T1FQB1|T1FQB1_HELRO
Uncharacterized protein
Search

tr|T1FQB2|T1FQB2_HELRO
Kynureninase
Search

KYNU

0.60	Kynureninase

0.77	GO:0006569	tryptophan catabolic process
0.75	GO:0097053	L-kynurenine catabolic process
0.75	GO:0043420	anthranilate metabolic process
0.74	GO:0034354	'de novo' NAD biosynthetic process from tryptophan
0.72	GO:0019805	quinolinate biosynthetic process
0.46	GO:0034516	response to vitamin B6
0.43	GO:0034341	response to interferon-gamma
0.35	GO:0006084	acetyl-CoA metabolic process

0.83	GO:0030429	kynureninase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.41	GO:0042803	protein homodimerization activity
0.32	GO:0016740	transferase activity

0.49	GO:0005737	cytoplasm
0.40	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.83

EC:3.7.1.3

GO:0030429

tr|T1FQB3|T1FQB3_HELRO
Uncharacterized protein
Search

tr|T1FQB4|T1FQB4_HELRO
Uncharacterized protein
Search

0.84	Putative swap mrna splicing regulator

0.49	GO:0001178	regulation of transcriptional start site selection at RNA polymerase II promoter
0.48	GO:0031440	regulation of mRNA 3'-end processing
0.47	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.44	GO:0008380	RNA splicing
0.44	GO:0006397	mRNA processing
0.41	GO:0032324	molybdopterin cofactor biosynthetic process
0.40	GO:0006777	Mo-molybdopterin cofactor biosynthetic process
0.36	GO:0006275	regulation of DNA replication
0.35	GO:0006260	DNA replication
0.35	GO:0007018	microtubule-based movement

0.48	GO:0008187	poly-pyrimidine tract binding
0.44	GO:0003729	mRNA binding
0.40	GO:0003700	DNA binding transcription factor activity
0.35	GO:0017111	nucleoside-triphosphatase activity
0.35	GO:0003677	DNA binding
0.34	GO:0005515	protein binding
0.34	GO:0003887	DNA-directed DNA polymerase activity
0.33	GO:1901265	nucleoside phosphate binding
0.33	GO:0036094	small molecule binding
0.33	GO:0016301	kinase activity

0.54	GO:0005654	nucleoplasm
0.38	GO:0034719	SMN-Sm protein complex
0.37	GO:0071011	precatalytic spliceosome
0.37	GO:0071013	catalytic step 2 spliceosome
0.36	GO:0030286	dynein complex
0.35	GO:0042025	host cell nucleus
0.34	GO:0000786	nucleosome
0.33	GO:0019028	viral capsid
0.30	GO:0016020	membrane

0.35

EC:3.6.1.15

GO:0017111

tr|T1FQB5|T1FQB5_HELRO
Uncharacterized protein
Search

tr|T1FQB6|T1FQB6_HELRO
Uncharacterized protein
Search

0.50	GO:0048734	proboscis morphogenesis
0.49	GO:0048802	notum morphogenesis
0.48	GO:0007527	adult somatic muscle development
0.48	GO:0051301	cell division
0.48	GO:0007049	cell cycle
0.48	GO:0030036	actin cytoskeleton organization
0.46	GO:0007026	negative regulation of microtubule depolymerization
0.46	GO:0060325	face morphogenesis
0.46	GO:0055002	striated muscle cell development
0.45	GO:0010927	cellular component assembly involved in morphogenesis

0.47	GO:0004386	helicase activity
0.43	GO:0004725	protein tyrosine phosphatase activity
0.43	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.42	GO:0005096	GTPase activator activity
0.42	GO:0005524	ATP binding
0.41	GO:0004674	protein serine/threonine kinase activity
0.40	GO:0003676	nucleic acid binding
0.39	GO:0008083	growth factor activity

0.55	GO:0005921	gap junction
0.53	GO:0005819	spindle
0.46	GO:0031941	filamentous actin
0.43	GO:0005815	microtubule organizing center
0.39	GO:0005737	cytoplasm
0.39	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.43

GO:0004725

tr|T1FQB7|T1FQB7_HELRO
Uncharacterized protein
Search

0.67	GO:0016192	vesicle-mediated transport
0.51	GO:0045682	regulation of epidermis development
0.35	GO:0016042	lipid catabolic process
0.34	GO:0006032	chitin catabolic process
0.34	GO:0071554	cell wall organization or biogenesis
0.34	GO:0055114	oxidation-reduction process
0.33	GO:0050794	regulation of cellular process
0.33	GO:0034220	ion transmembrane transport
0.33	GO:0023052	signaling
0.33	GO:0007154	cell communication

0.40	GO:0045296	cadherin binding
0.39	GO:0030276	clathrin binding
0.36	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.35	GO:0020037	heme binding
0.35	GO:0005506	iron ion binding
0.34	GO:0004568	chitinase activity
0.34	GO:0005216	ion channel activity
0.34	GO:0004888	transmembrane signaling receptor activity
0.34	GO:0030248	cellulose binding
0.34	GO:0045330	aspartyl esterase activity

0.70	GO:0005794	Golgi apparatus
0.37	GO:0005654	nucleoplasm
0.33	GO:0005618	cell wall
0.33	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.36

EC:1.14

GO:0016705

tr|T1FQB8|T1FQB8_HELRO
Uncharacterized protein
Search

tr|T1FQB9|T1FQB9_HELRO
Uncharacterized protein
Search

0.47	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.47	GO:2001141	regulation of RNA biosynthetic process
0.47	GO:0010468	regulation of gene expression
0.42	GO:0006325	chromatin organization
0.41	GO:0036211	protein modification process
0.41	GO:0044267	cellular protein metabolic process
0.38	GO:0106074	aminoacyl-tRNA metabolism involved in translational fidelity
0.38	GO:0043414	macromolecule methylation
0.37	GO:0043039	tRNA aminoacylation
0.37	GO:0010467	gene expression

0.49	GO:0140110	transcription regulator activity
0.40	GO:0018024	histone-lysine N-methyltransferase activity
0.40	GO:0003676	nucleic acid binding
0.40	GO:0046872	metal ion binding
0.39	GO:0046983	protein dimerization activity
0.38	GO:0030554	adenyl nucleotide binding
0.38	GO:0016788	hydrolase activity, acting on ester bonds
0.38	GO:0032553	ribonucleotide binding
0.38	GO:0008144	drug binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding

0.42	GO:0005634	nucleus
0.37	GO:0031248	protein acetyltransferase complex
0.37	GO:1905368	peptidase complex
0.36	GO:0005667	transcription factor complex
0.36	GO:0070013	intracellular organelle lumen
0.36	GO:0044446	intracellular organelle part
0.35	GO:0005935	cellular bud neck
0.35	GO:0000932	P-body
0.35	GO:0010494	cytoplasmic stress granule
0.30	GO:0016020	membrane

0.40	EC:2.1.1.43	GO:0018024
0.37	KEGG:R03656	GO:0004822

tr|T1FQC0|T1FQC0_HELRO
Uncharacterized protein
Search

0.74	IQ and AAA domain-containing protein 1 isoform C

0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0016887	ATPase activity

0.34

GO:0016887

tr|T1FQC1|T1FQC1_HELRO
Uncharacterized protein
Search

tr|T1FQC2|T1FQC2_HELRO
Uncharacterized protein
Search

tr|T1FQC3|T1FQC3_HELRO
Inhibitor of growth protein
Search

ING3

0.51	Inhibitor of growth protein 3

0.71	GO:0016569	covalent chromatin modification
0.53	GO:0043065	positive regulation of apoptotic process
0.53	GO:0018393	internal peptidyl-lysine acetylation
0.40	GO:0040008	regulation of growth
0.36	GO:0006351	transcription, DNA-templated
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:0010468	regulation of gene expression

0.54	GO:0140034	methylation-dependent protein binding
0.54	GO:0004402	histone acetyltransferase activity
0.52	GO:0042393	histone binding
0.52	GO:0046872	metal ion binding

0.83	GO:0000812	Swr1 complex
0.79	GO:0035267	NuA4 histone acetyltransferase complex

0.54

GO:0004402

tr|T1FQC4|T1FQC4_HELRO
Uncharacterized protein
Search

CCDC102A

0.49	Coiled-coil domain-containing protein 102A

0.35

GO:0016032

viral process

0.73

GO:0003774

motor activity

0.77

GO:0016459

myosin complex

tr|T1FQC5|T1FQC5_HELRO
Uncharacterized protein
Search

tr|T1FQC6|T1FQC6_HELRO
Uncharacterized protein
Search

tr|T1FQC7|T1FQC7_HELRO
Uncharacterized protein
Search

tr|T1FQC8|T1FQC8_HELRO
Uncharacterized protein
Search

MYO7A

0.87	Unconventional myosin-X

0.73	GO:0007018	microtubule-based movement
0.40	GO:0050957	equilibrioception
0.40	GO:0060088	auditory receptor cell stereocilium organization
0.40	GO:0001845	phagolysosome assembly
0.39	GO:0051904	pigment granule transport
0.39	GO:0030048	actin filament-based movement
0.39	GO:0048563	post-embryonic animal organ morphogenesis
0.38	GO:0007605	sensory perception of sound
0.38	GO:0007601	visual perception
0.36	GO:0006886	intracellular protein transport

0.75	GO:0051015	actin filament binding
0.74	GO:0003777	microtubule motor activity
0.73	GO:0008017	microtubule binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0000146	microfilament motor activity
0.39	GO:0030507	spectrin binding
0.38	GO:0005516	calmodulin binding
0.38	GO:0019904	protein domain specific binding

0.76	GO:0016459	myosin complex
0.39	GO:0001917	photoreceptor inner segment
0.39	GO:0032391	photoreceptor connecting cilium
0.39	GO:0032420	stereocilium
0.39	GO:0042470	melanosome
0.39	GO:0001750	photoreceptor outer segment
0.38	GO:0005765	lysosomal membrane
0.38	GO:0016324	apical plasma membrane
0.37	GO:0045202	synapse
0.36	GO:0005829	cytosol

tr|T1FQC9|T1FQC9_HELRO
Uncharacterized protein
Search

tr|T1FQD0|T1FQD0_HELRO
Uncharacterized protein
Search

tr|T1FQD1|T1FQD1_HELRO
Uncharacterized protein
Search

tr|T1FQD2|T1FQD2_HELRO
Uncharacterized protein
Search

tr|T1FQD3|T1FQD3_HELRO
Uncharacterized protein
Search

tr|T1FQD4|T1FQD4_HELRO
Uncharacterized protein
Search

tr|T1FQD5|T1FQD5_HELRO
Uncharacterized protein
Search

0.10	Integrator complex subunit 9

0.82	GO:0016180	snRNA processing
0.35	GO:0042795	snRNA transcription by RNA polymerase II
0.33	GO:2001141	regulation of RNA biosynthetic process
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.33	GO:0005515	protein binding
0.33	GO:0003677	DNA binding

0.82	GO:0032039	integrator complex
0.48	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|T1FQD6|T1FQD6_HELRO
Ubiquitin carboxyl-terminal hydrolase
Search

0.38	Ubiquitin carboxyl-terminal hydrolase

0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.54	GO:0061519	macrophage homeostasis
0.54	GO:0035521	monoubiquitinated histone deubiquitination
0.52	GO:0071108	protein K48-linked deubiquitination
0.51	GO:1900015	regulation of cytokine production involved in inflammatory response
0.50	GO:0001558	regulation of cell growth
0.50	GO:1903955	positive regulation of protein targeting to mitochondrion
0.47	GO:0051726	regulation of cell cycle
0.46	GO:0010035	response to inorganic substance
0.35	GO:1904888	cranial skeletal system development

0.80	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.49	GO:0003682	chromatin binding
0.33	GO:0005515	protein binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003676	nucleic acid binding

0.55	GO:0035517	PR-DUB complex
0.44	GO:0005654	nucleoplasm
0.44	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|T1FQD7|T1FQD7_HELRO
Uncharacterized protein
Search

MED19

0.97	Mediator of RNA polymerase II transcription subunit 19

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.58	GO:0006351	transcription, DNA-templated
0.43	GO:0045893	positive regulation of transcription, DNA-templated
0.34	GO:0098734	macromolecule depalmitoylation
0.32	GO:0006520	cellular amino acid metabolic process
0.32	GO:0036068	light-independent chlorophyll biosynthetic process
0.32	GO:0019685	photosynthesis, dark reaction
0.31	GO:0055114	oxidation-reduction process

0.79	GO:0001104	RNA polymerase II transcription cofactor activity
0.43	GO:0008134	transcription factor binding
0.34	GO:0098599	palmitoyl hydrolase activity
0.33	GO:0016831	carboxy-lyase activity
0.33	GO:0030170	pyridoxal phosphate binding
0.32	GO:0003723	RNA binding
0.32	GO:0046872	metal ion binding
0.32	GO:0016636	oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor
0.32	GO:0016730	oxidoreductase activity, acting on iron-sulfur proteins as donors
0.32	GO:0051539	4 iron, 4 sulfur cluster binding

0.77	GO:0016592	mediator complex
0.32	GO:0009507	chloroplast
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:4.1.1

GO:0016831

tr|T1FQD8|T1FQD8_HELRO
Uncharacterized protein
Search

LIN7C

0.58	Receptor targeting protein Lin-7

0.76	GO:0099643	signal release from synapse
0.76	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.71	GO:0006887	exocytosis
0.70	GO:0006836	neurotransmitter transport
0.67	GO:0001505	regulation of neurotransmitter levels
0.64	GO:0051649	establishment of localization in cell
0.61	GO:0015031	protein transport
0.50	GO:0060429	epithelium development
0.49	GO:0045199	maintenance of epithelial cell apical/basal polarity
0.48	GO:1903361	protein localization to basolateral plasma membrane

0.83	GO:0097016	L27 domain binding
0.44	GO:0008092	cytoskeletal protein binding
0.36	GO:0030165	PDZ domain binding
0.34	GO:0004364	glutathione transferase activity
0.33	GO:0016757	transferase activity, transferring glycosyl groups
0.33	GO:0032403	protein complex binding

0.82	GO:0097025	MPP7-DLG1-LIN7 complex
0.76	GO:0016323	basolateral plasma membrane
0.73	GO:0098793	presynapse
0.52	GO:0005911	cell-cell junction
0.45	GO:0045211	postsynaptic membrane
0.38	GO:0014069	postsynaptic density
0.37	GO:0043005	neuron projection
0.37	GO:0005737	cytoplasm
0.34	GO:0070062	extracellular exosome
0.33	GO:0030529	intracellular ribonucleoprotein complex

0.34

EC:2.5.1.18

GO:0004364

tr|T1FQD9|T1FQD9_HELRO
Uncharacterized protein
Search

DNAJC25

0.51	DnaJ domain containing protein 5

0.33

GO:0007186

G-protein coupled receptor signaling pathway

0.33

GO:0004871

signal transducer activity

0.34	GO:1905360	GTPase complex
0.34	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.33	GO:0012505	endomembrane system
0.33	GO:0098797	plasma membrane protein complex
0.30	GO:0031224	intrinsic component of membrane

tr|T1FQE0|T1FQE0_HELRO
Uncharacterized protein
Search

tr|T1FQE1|T1FQE1_HELRO
Uncharacterized protein
Search

tr|T1FQE2|T1FQE2_HELRO
Uncharacterized protein
Search

tr|T1FQE3|T1FQE3_HELRO
Uncharacterized protein
Search

0.54	GO:0016579	protein deubiquitination
0.52	GO:0006511	ubiquitin-dependent protein catabolic process
0.41	GO:0051649	establishment of localization in cell
0.39	GO:0006457	protein folding
0.39	GO:0006810	transport
0.38	GO:0019725	cellular homeostasis
0.38	GO:0050794	regulation of cellular process
0.37	GO:0030421	defecation
0.37	GO:0031581	hemidesmosome assembly
0.37	GO:0009636	response to toxic substance

0.54	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.40	GO:0005509	calcium ion binding
0.40	GO:0051082	unfolded protein binding
0.37	GO:0005262	calcium channel activity
0.37	GO:0005217	intracellular ligand-gated ion channel activity
0.36	GO:0140135	mechanosensitive cation channel activity
0.36	GO:0008270	zinc ion binding
0.35	GO:0016772	transferase activity, transferring phosphorus-containing groups
0.35	GO:0001104	RNA polymerase II transcription cofactor activity
0.35	GO:0003777	microtubule motor activity

0.47	GO:0005856	cytoskeleton
0.40	GO:0043227	membrane-bounded organelle
0.39	GO:0012505	endomembrane system
0.38	GO:0044444	cytoplasmic part
0.35	GO:0044446	intracellular organelle part
0.35	GO:0044421	extracellular region part
0.35	GO:0044815	DNA packaging complex
0.35	GO:0070013	intracellular organelle lumen
0.35	GO:0032993	protein-DNA complex
0.34	GO:0005694	chromosome

0.54	EC:3.4.19.12	GO:0036459
0.33	KEGG:R00630	GO:0052689

tr|T1FQE4|T1FQE4_HELRO
Uncharacterized protein
Search

CTDNEP1

0.94	Serine/threonine-protein phosphatase dullard-A

0.68	GO:0016311	dephosphorylation
0.55	GO:0010867	positive regulation of triglyceride biosynthetic process
0.53	GO:0006998	nuclear envelope organization
0.50	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.50	GO:0007498	mesoderm development
0.49	GO:0034504	protein localization to nucleus
0.48	GO:0007276	gamete generation
0.43	GO:0036211	protein modification process
0.41	GO:0044267	cellular protein metabolic process
0.35	GO:0007399	nervous system development

0.69	GO:0016791	phosphatase activity
0.42	GO:0140096	catalytic activity, acting on a protein
0.34	GO:0005515	protein binding
0.32	GO:0046872	metal ion binding

0.54	GO:0071595	Nem1-Spo7 phosphatase complex
0.51	GO:0005811	lipid droplet
0.50	GO:0031965	nuclear membrane
0.47	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0048471	perinuclear region of cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.69

EC:3.1.3 EC:3.1.3.41

GO:0016791

tr|T1FQE5|T1FQE5_HELRO
Uncharacterized protein
Search

0.76	GO:0006071	glycerol metabolic process
0.57	GO:0016310	phosphorylation
0.43	GO:0039534	negative regulation of MDA-5 signaling pathway
0.40	GO:0097237	cellular response to toxic substance
0.35	GO:0019662	non-glycolytic fermentation
0.34	GO:0019405	alditol catabolic process

0.79	GO:0004371	glycerone kinase activity
0.50	GO:0032559	adenyl ribonucleotide binding
0.49	GO:0008144	drug binding
0.49	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0050354	triokinase activity
0.43	GO:0034012	FAD-AMP lyase (cyclizing) activity
0.34	GO:0004408	holocytochrome-c synthase activity

0.33	GO:0005829	cytosol
0.32	GO:0005739	mitochondrion

0.79	EC:2.7.1.29	GO:0004371
0.79	KEGG:R01011	GO:0004371

tr|T1FQE6|T1FQE6_HELRO
Uncharacterized protein
Search

tr|T1FQE7|T1FQE7_HELRO
Uncharacterized protein
Search

tr|T1FQE8|T1FQE8_HELRO
Uncharacterized protein
Search

0.52	Sterile alpha motif containing protein (Fragment)

0.71	GO:0050808	synapse organization
0.48	GO:0099643	signal release from synapse
0.48	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.46	GO:0006836	neurotransmitter transport
0.45	GO:0001505	regulation of neurotransmitter levels
0.45	GO:0051649	establishment of localization in cell
0.41	GO:1903744	positive regulation of anterograde synaptic vesicle transport
0.41	GO:1905608	positive regulation of presynapse assembly
0.39	GO:2000582	positive regulation of ATP-dependent microtubule motor activity, plus-end-directed
0.39	GO:0018991	oviposition

0.39	GO:0030159	receptor signaling complex scaffold activity
0.39	GO:0019894	kinesin binding
0.37	GO:0042803	protein homodimerization activity
0.32	GO:0016491	oxidoreductase activity

0.76	GO:0045202	synapse
0.58	GO:0097458	neuron part
0.37	GO:0001669	acrosomal vesicle
0.37	GO:0120025	plasma membrane bounded cell projection
0.35	GO:0098875	epididymosome
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.32

GO:0016491

tr|T1FQE9|T1FQE9_HELRO
Uncharacterized protein
Search

0.37	GO:2000584	negative regulation of platelet-derived growth factor receptor-alpha signaling pathway
0.37	GO:2000790	regulation of mesenchymal cell proliferation involved in lung development
0.37	GO:0072201	negative regulation of mesenchymal cell proliferation
0.36	GO:0048286	lung alveolus development
0.35	GO:0051093	negative regulation of developmental process
0.35	GO:0000122	negative regulation of transcription by RNA polymerase II
0.35	GO:0051241	negative regulation of multicellular organismal process
0.32	GO:0016310	phosphorylation

0.53	GO:0046872	metal ion binding
0.32	GO:0003700	DNA binding transcription factor activity
0.32	GO:0016301	kinase activity
0.31	GO:0003677	DNA binding

0.34	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|T1FQF0|T1FQF0_HELRO
Uncharacterized protein
Search

0.56	GO:0006413	translational initiation
0.54	GO:0031323	regulation of cellular metabolic process
0.54	GO:0051171	regulation of nitrogen compound metabolic process
0.54	GO:0060255	regulation of macromolecule metabolic process
0.54	GO:0080090	regulation of primary metabolic process
0.52	GO:0009889	regulation of biosynthetic process
0.51	GO:0097659	nucleic acid-templated transcription
0.50	GO:0007050	cell cycle arrest
0.49	GO:0051348	negative regulation of transferase activity
0.43	GO:0009892	negative regulation of metabolic process

0.60	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.58	GO:0046983	protein dimerization activity
0.56	GO:0003743	translation initiation factor activity
0.51	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity
0.49	GO:0003700	DNA binding transcription factor activity
0.37	GO:0010484	H3 histone acetyltransferase activity
0.36	GO:0046872	metal ion binding
0.36	GO:0050825	ice binding
0.35	GO:0140096	catalytic activity, acting on a protein
0.35	GO:0016301	kinase activity

0.57	GO:0005634	nucleus
0.53	GO:0000428	DNA-directed RNA polymerase complex
0.53	GO:0005667	transcription factor complex
0.49	GO:0070013	intracellular organelle lumen
0.45	GO:0044446	intracellular organelle part
0.36	GO:0098588	bounding membrane of organelle
0.36	GO:0005764	lysosome
0.36	GO:0098805	whole membrane
0.34	GO:0005794	Golgi apparatus
0.34	GO:0005694	chromosome

0.34

GO:0016773

tr|T1FQF1|T1FQF1_HELRO
Uncharacterized protein
Search

0.61	GO:0006707	cholesterol catabolic process
0.61	GO:0006699	bile acid biosynthetic process
0.60	GO:0071333	cellular response to glucose stimulus
0.59	GO:0042632	cholesterol homeostasis
0.53	GO:0055114	oxidation-reduction process
0.38	GO:0046457	prostanoid biosynthetic process
0.38	GO:0006693	prostaglandin metabolic process
0.38	GO:0070857	regulation of bile acid biosynthetic process
0.36	GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway
0.35	GO:0045019	negative regulation of nitric oxide biosynthetic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.64	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.39	GO:0008116	prostaglandin-I synthase activity

0.64	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0005901	caveola
0.33	GO:0031090	organelle membrane
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.68	EC:1.14	GO:0016705
0.39	KEGG:R02267	GO:0008116

tr|T1FQF2|T1FQF2_HELRO
Uncharacterized protein
Search

GAS8

0.93	Growth arrest-specific protein 8

0.71	GO:0048870	cell motility
0.52	GO:0003341	cilium movement
0.48	GO:1904526	regulation of microtubule binding
0.46	GO:0034613	cellular protein localization
0.45	GO:0035082	axoneme assembly
0.45	GO:0007368	determination of left/right symmetry
0.44	GO:0007420	brain development
0.38	GO:0045880	positive regulation of smoothened signaling pathway
0.37	GO:0055001	muscle cell development
0.36	GO:0015937	coenzyme A biosynthetic process

0.51	GO:0017137	Rab GTPase binding
0.43	GO:0008017	microtubule binding
0.36	GO:0004594	pantothenate kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.80	GO:0031514	motile cilium
0.52	GO:0005930	axoneme
0.51	GO:0005874	microtubule
0.47	GO:0005794	Golgi apparatus
0.45	GO:0036064	ciliary basal body
0.45	GO:0097223	sperm part

0.36

EC:2.7.1.33

GO:0004594

tr|T1FQF3|T1FQF3_HELRO
Uncharacterized protein
Search

tr|T1FQF4|T1FQF4_HELRO
Uncharacterized protein
Search

tr|T1FQF5|T1FQF5_HELRO
Uncharacterized protein
Search

tr|T1FQF6|T1FQF6_HELRO
Uncharacterized protein
Search

0.63	GO:0007346	regulation of mitotic cell cycle
0.60	GO:0071900	regulation of protein serine/threonine kinase activity
0.59	GO:0044387	negative regulation of protein kinase activity by regulation of protein phosphorylation
0.59	GO:0071569	protein ufmylation
0.58	GO:1901798	positive regulation of signal transduction by p53 class mediator
0.57	GO:0030262	apoptotic nuclear changes
0.57	GO:1904029	regulation of cyclin-dependent protein kinase activity
0.57	GO:0031572	G2 DNA damage checkpoint
0.56	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.56	GO:1903363	negative regulation of cellular protein catabolic process

0.59	GO:0097371	MDM2/MDM4 family protein binding
0.58	GO:0051019	mitogen-activated protein kinase binding
0.58	GO:0051059	NF-kappaB binding
0.55	GO:0030332	cyclin binding
0.53	GO:0044389	ubiquitin-like protein ligase binding
0.44	GO:0050825	ice binding
0.42	GO:0017137	Rab GTPase binding
0.41	GO:0050072	m7G(5')pppN diphosphatase activity
0.41	GO:0003712	transcription cofactor activity
0.39	GO:0140096	catalytic activity, acting on a protein

0.53	GO:0005813	centrosome
0.51	GO:0099513	polymeric cytoskeletal fiber
0.50	GO:0005730	nucleolus
0.50	GO:0012505	endomembrane system
0.48	GO:0005829	cytosol
0.45	GO:0043234	protein complex
0.39	GO:0000932	P-body
0.38	GO:0015629	actin cytoskeleton
0.35	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.41

EC:3.6.1.30

GO:0050072

tr|T1FQF7|T1FQF7_HELRO
Uncharacterized protein
Search

0.52	GO:0035556	intracellular signal transduction
0.43	GO:0006468	protein phosphorylation
0.40	GO:0018212	peptidyl-tyrosine modification
0.36	GO:0043326	chemotaxis to folate
0.36	GO:0060176	regulation of aggregation involved in sorocarp development
0.36	GO:0007018	microtubule-based movement
0.36	GO:0043327	chemotaxis to cAMP
0.36	GO:0031272	regulation of pseudopodium assembly
0.36	GO:0018095	protein polyglutamylation
0.36	GO:0006886	intracellular protein transport

0.43	GO:0004672	protein kinase activity
0.41	GO:0032559	adenyl ribonucleotide binding
0.41	GO:0008144	drug binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0046872	metal ion binding
0.36	GO:0003777	microtubule motor activity
0.36	GO:0008017	microtubule binding
0.36	GO:0003700	DNA binding transcription factor activity
0.36	GO:0098772	molecular function regulator
0.35	GO:0030248	cellulose binding

0.41	GO:0005622	intracellular
0.36	GO:0048475	coated membrane
0.35	GO:0043227	membrane-bounded organelle
0.35	GO:0098796	membrane protein complex
0.34	GO:0099512	supramolecular fiber
0.34	GO:0043228	non-membrane-bounded organelle
0.34	GO:0005576	extracellular region
0.34	GO:0012505	endomembrane system
0.34	GO:0044422	organelle part
0.34	GO:0031974	membrane-enclosed lumen

0.34

GO:0004553

tr|T1FQF8|T1FQF8_HELRO
Uncharacterized protein
Search

0.51	Complement C1q tumor necrosis factor-related protein 3

0.44	GO:0060414	aorta smooth muscle tissue morphogenesis
0.43	GO:2001223	negative regulation of neuron migration
0.43	GO:0035025	positive regulation of Rho protein signal transduction
0.42	GO:0030199	collagen fibril organization
0.42	GO:0021987	cerebral cortex development
0.42	GO:0071230	cellular response to amino acid stimulus
0.42	GO:0018149	peptide cross-linking
0.42	GO:0043588	skin development
0.42	GO:0048565	digestive tract development
0.41	GO:0007179	transforming growth factor beta receptor signaling pathway

0.54	GO:0005201	extracellular matrix structural constituent
0.43	GO:0048407	platelet-derived growth factor binding
0.42	GO:0046332	SMAD binding
0.42	GO:0005178	integrin binding
0.42	GO:0002020	protease binding
0.40	GO:0042302	structural constituent of cuticle

0.58	GO:0005581	collagen trimer
0.49	GO:0044420	extracellular matrix component
0.47	GO:0005578	proteinaceous extracellular matrix
0.39	GO:0005615	extracellular space
0.39	GO:0099512	supramolecular fiber
0.30	GO:0016020	membrane

tr|T1FQF9|T1FQF9_HELRO
Uncharacterized protein
Search

0.30

GO:0044425

membrane part

tr|T1FQG0|T1FQG0_HELRO
Uncharacterized protein
Search

tr|T1FQG1|T1FQG1_HELRO
Uncharacterized protein
Search

tr|T1FQG2|T1FQG2_HELRO
Uncharacterized protein
Search

0.85	GO:0000012	single strand break repair
0.36	GO:0006284	base-excision repair
0.33	GO:0009405	pathogenesis
0.33	GO:0007605	sensory perception of sound
0.33	GO:0009253	peptidoglycan catabolic process
0.32	GO:0032259	methylation
0.32	GO:0006508	proteolysis

0.72	GO:0003684	damaged DNA binding
0.36	GO:0005509	calcium ion binding
0.34	GO:0003723	RNA binding
0.33	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity
0.33	GO:0051015	actin filament binding
0.33	GO:0004386	helicase activity
0.32	GO:0004252	serine-type endopeptidase activity
0.32	GO:0008168	methyltransferase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding

0.61	GO:0005634	nucleus
0.33	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.33

EC:3.5.1.28

GO:0008745

tr|T1FQG3|T1FQG3_HELRO
Uncharacterized protein
Search

tr|T1FQG4|T1FQG4_HELRO
Uncharacterized protein
Search

0.68	GO:0006397	mRNA processing
0.38	GO:0060997	dendritic spine morphogenesis
0.38	GO:0021952	central nervous system projection neuron axonogenesis
0.37	GO:0007411	axon guidance
0.37	GO:0060548	negative regulation of cell death
0.34	GO:0006508	proteolysis
0.34	GO:0007062	sister chromatid cohesion
0.34	GO:0030261	chromosome condensation
0.34	GO:0007018	microtubule-based movement
0.34	GO:0006259	DNA metabolic process

0.56	GO:0003723	RNA binding
0.48	GO:0046872	metal ion binding
0.36	GO:0008234	cysteine-type peptidase activity
0.35	GO:0050825	ice binding
0.34	GO:0003777	microtubule motor activity
0.34	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0003700	DNA binding transcription factor activity

0.37	GO:0005634	nucleus
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.36	EC:3.4	GO:0008234
0.34	KEGG:R03876	GO:0004842

tr|T1FQG5|T1FQG5_HELRO
Uncharacterized protein
Search

tr|T1FQG6|T1FQG6_HELRO
Uncharacterized protein
Search

0.54	GO:0018095	protein polyglutamylation
0.43	GO:0016180	snRNA processing
0.41	GO:0055085	transmembrane transport
0.38	GO:0009452	7-methylguanosine RNA capping
0.38	GO:0006511	ubiquitin-dependent protein catabolic process
0.38	GO:0016567	protein ubiquitination
0.37	GO:0032259	methylation
0.37	GO:0099120	socially cooperative development
0.36	GO:0017182	peptidyl-diphthamide metabolic process
0.36	GO:1900247	regulation of cytoplasmic translational elongation

0.47	GO:0043492	ATPase activity, coupled to movement of substances
0.47	GO:0030554	adenyl nucleotide binding
0.46	GO:0015399	primary active transmembrane transporter activity
0.46	GO:0032555	purine ribonucleotide binding
0.46	GO:0008144	drug binding
0.46	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0003723	RNA binding
0.39	GO:0061630	ubiquitin protein ligase activity
0.38	GO:0046983	protein dimerization activity
0.38	GO:0004835	tubulin-tyrosine ligase activity

0.44	GO:0032039	integrator complex
0.36	GO:0005615	extracellular space
0.36	GO:0000151	ubiquitin ligase complex
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.38

EC:6.3.2.25

GO:0004835

tr|T1FQG7|T1FQG7_HELRO
Uncharacterized protein
Search

tr|T1FQG8|T1FQG8_HELRO
Uncharacterized protein
Search

tr|T1FQG9|T1FQG9_HELRO
Uncharacterized protein
Search

0.53	GO:0001764	neuron migration
0.51	GO:0007417	central nervous system development
0.41	GO:0060255	regulation of macromolecule metabolic process
0.41	GO:0043412	macromolecule modification
0.40	GO:0043085	positive regulation of catalytic activity
0.40	GO:0031323	regulation of cellular metabolic process
0.40	GO:0051171	regulation of nitrogen compound metabolic process
0.40	GO:0080090	regulation of primary metabolic process
0.40	GO:0099120	socially cooperative development
0.39	GO:0046700	heterocycle catabolic process

0.54	GO:0070325	lipoprotein particle receptor binding
0.39	GO:0008270	zinc ion binding
0.39	GO:0003700	DNA binding transcription factor activity
0.39	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.38	GO:0008047	enzyme activator activity
0.37	GO:0003676	nucleic acid binding
0.37	GO:0019787	ubiquitin-like protein transferase activity
0.37	GO:0031386	protein tag
0.37	GO:0009982	pseudouridine synthase activity
0.37	GO:0004037	allantoicase activity

0.40	GO:0005634	nucleus
0.37	GO:0005667	transcription factor complex
0.36	GO:0030014	CCR4-NOT complex
0.36	GO:0030425	dendrite
0.35	GO:0031248	protein acetyltransferase complex
0.35	GO:0005578	proteinaceous extracellular matrix
0.35	GO:0000428	DNA-directed RNA polymerase complex
0.35	GO:0005615	extracellular space
0.35	GO:1905368	peptidase complex
0.34	GO:0070013	intracellular organelle lumen

0.39	EC:2.7.10.2	GO:0004715
0.37	KEGG:R02422	GO:0004037

tr|T1FQH0|T1FQH0_HELRO
Uncharacterized protein
Search

0.44	GO:1902476	chloride transmembrane transport
0.43	GO:0019674	NAD metabolic process
0.42	GO:0032774	RNA biosynthetic process
0.41	GO:2001141	regulation of RNA biosynthetic process
0.41	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.41	GO:0010468	regulation of gene expression
0.40	GO:0032259	methylation
0.39	GO:1900089	negative regulation of inositol biosynthetic process
0.39	GO:1900468	regulation of phosphatidylserine biosynthetic process
0.39	GO:0016310	phosphorylation

0.45	GO:0005247	voltage-gated chloride channel activity
0.44	GO:0003951	NAD+ kinase activity
0.42	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.41	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.40	GO:0008168	methyltransferase activity
0.40	GO:0046872	metal ion binding
0.39	GO:0003677	DNA binding
0.38	GO:0070491	repressing transcription factor binding
0.37	GO:0001067	regulatory region nucleic acid binding
0.36	GO:0000989	transcription factor activity, transcription factor binding

0.43	GO:0005634	nucleus
0.39	GO:0005576	extracellular region
0.37	GO:0000785	chromatin
0.37	GO:0070013	intracellular organelle lumen
0.36	GO:1902494	catalytic complex
0.35	GO:0009277	fungal-type cell wall
0.35	GO:0031225	anchored component of membrane
0.34	GO:0036338	viral membrane
0.34	GO:0030117	membrane coat
0.33	GO:0031966	mitochondrial membrane

0.44	EC:2.7.1.23	GO:0003951
0.44	KEGG:R00104	GO:0003951

tr|T1FQH1|T1FQH1_HELRO
Uncharacterized protein
Search

tr|T1FQH2|T1FQH2_HELRO
Uncharacterized protein
Search

tr|T1FQH3|T1FQH3_HELRO
Sodium/potassium-transporting ATPase subunit alpha
Search

0.46	Sodium/potassium-transporting ATPase subunit alpha

0.79	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient
0.70	GO:0090662	ATP hydrolysis coupled transmembrane transport
0.68	GO:0006814	sodium ion transport
0.67	GO:0006813	potassium ion transport
0.39	GO:0099132	ATP hydrolysis coupled cation transmembrane transport

0.79	GO:0005391	sodium:potassium-exchanging ATPase activity
0.53	GO:0030554	adenyl nucleotide binding
0.52	GO:0097367	carbohydrate derivative binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0046872	metal ion binding

0.30

GO:0016020

membrane

0.79

EC:3.6.3.9

GO:0005391

tr|T1FQH4|T1FQH4_HELRO
Uncharacterized protein
Search

CISD3

0.42	CDGSH iron-sulfur domain-containing protein 3 mitochondrial

0.46	GO:0006537	glutamate biosynthetic process
0.38	GO:0055114	oxidation-reduction process

0.71	GO:0051537	2 iron, 2 sulfur cluster binding
0.46	GO:0015930	glutamate synthase activity
0.34	GO:0016639	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
0.33	GO:0046872	metal ion binding

0.56	GO:0043231	intracellular membrane-bounded organelle
0.37	GO:0044444	cytoplasmic part
0.30	GO:0031224	intrinsic component of membrane

0.46

EC:1.4

GO:0015930

tr|T1FQH5|T1FQH5_HELRO
Uncharacterized protein
Search

tr|T1FQH6|T1FQH6_HELRO
Uncharacterized protein
Search

LDB1

0.63	LIM domain-binding protein 2

0.70	GO:0006357	regulation of transcription by RNA polymerase II
0.55	GO:0007563	regulation of eclosion
0.55	GO:0060429	epithelium development
0.55	GO:0045893	positive regulation of transcription, DNA-templated
0.55	GO:0010669	epithelial structure maintenance
0.55	GO:0035019	somatic stem cell population maintenance
0.54	GO:0070983	dendrite guidance
0.54	GO:0048513	animal organ development
0.51	GO:0030334	regulation of cell migration
0.51	GO:0035120	post-embryonic appendage morphogenesis

0.84	GO:0030274	LIM domain binding
0.71	GO:0000989	transcription factor activity, transcription factor binding
0.51	GO:0001085	RNA polymerase II transcription factor binding
0.48	GO:0019899	enzyme binding
0.38	GO:0003682	chromatin binding
0.33	GO:0003677	DNA binding

0.61	GO:0005634	nucleus
0.52	GO:0031252	cell leading edge
0.50	GO:0005667	transcription factor complex
0.47	GO:0031974	membrane-enclosed lumen
0.43	GO:0043232	intracellular non-membrane-bounded organelle
0.43	GO:0044446	intracellular organelle part
0.42	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1FQH7|T1FQH7_HELRO
Uncharacterized protein
Search

0.78	GO:1990564	protein polyufmylation
0.76	GO:0033146	regulation of intracellular estrogen receptor signaling pathway
0.74	GO:1902065	response to L-glutamate
0.74	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.73	GO:0031397	negative regulation of protein ubiquitination
0.72	GO:0060252	positive regulation of glial cell proliferation
0.71	GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process
0.68	GO:0034976	response to endoplasmic reticulum stress
0.64	GO:0032880	regulation of protein localization
0.44	GO:0043066	negative regulation of apoptotic process

0.80	GO:0071568	UFM1 transferase activity
0.54	GO:0016874	ligase activity
0.38	GO:0005515	protein binding
0.35	GO:0004871	signal transducer activity

0.63	GO:0043005	neuron projection
0.62	GO:0005789	endoplasmic reticulum membrane
0.53	GO:0043234	protein complex
0.43	GO:0005829	cytosol
0.38	GO:1905360	GTPase complex
0.38	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane

0.54

GO:0016874

tr|T1FQH8|T1FQH8_HELRO
Uncharacterized protein
Search

TAF5

0.57	Transcription initiation factor TFIID subunit

0.61	GO:0006413	translational initiation
0.59	GO:0006367	transcription initiation from RNA polymerase II promoter
0.56	GO:0016573	histone acetylation
0.46	GO:2001141	regulation of RNA biosynthetic process
0.46	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.46	GO:0010468	regulation of gene expression
0.42	GO:0007219	Notch signaling pathway
0.42	GO:0070897	DNA-templated transcriptional preinitiation complex assembly
0.40	GO:0051254	positive regulation of RNA metabolic process
0.40	GO:0010557	positive regulation of macromolecule biosynthetic process

0.62	GO:0003743	translation initiation factor activity
0.57	GO:0004402	histone acetyltransferase activity
0.55	GO:0044212	transcription regulatory region DNA binding
0.54	GO:0042802	identical protein binding
0.51	GO:0046983	protein dimerization activity
0.48	GO:0003700	DNA binding transcription factor activity

0.62	GO:0033276	transcription factor TFTC complex
0.59	GO:0005669	transcription factor TFIID complex
0.54	GO:0000790	nuclear chromatin
0.54	GO:0015629	actin cytoskeleton
0.37	GO:0030914	STAGA complex
0.36	GO:0005730	nucleolus
0.33	GO:0019013	viral nucleocapsid
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0031224	intrinsic component of membrane

0.57

GO:0004402

tr|T1FQH9|T1FQH9_HELRO
Uncharacterized protein
Search

0.61	GO:0006508	proteolysis
0.49	GO:0002002	regulation of angiotensin levels in blood
0.40	GO:0042730	fibrinolysis
0.37	GO:0009057	macromolecule catabolic process
0.37	GO:0043413	macromolecule glycosylation
0.37	GO:0009101	glycoprotein biosynthetic process
0.36	GO:0005976	polysaccharide metabolic process
0.36	GO:0016052	carbohydrate catabolic process
0.35	GO:0044267	cellular protein metabolic process
0.35	GO:0036211	protein modification process

0.78	GO:0004181	metallocarboxypeptidase activity
0.63	GO:0008270	zinc ion binding
0.37	GO:0008378	galactosyltransferase activity
0.35	GO:0070003	threonine-type peptidase activity
0.34	GO:0005254	chloride channel activity
0.34	GO:0004175	endopeptidase activity

0.45	GO:0044421	extracellular region part
0.35	GO:0005839	proteasome core complex
0.35	GO:0034707	chloride channel complex
0.34	GO:0005634	nucleus
0.33	GO:0005886	plasma membrane

0.78

EC:3.4.17

GO:0004181

tr|T1FQI0|T1FQI0_HELRO
Polypeptide N-acetylgalactosaminyltransferase
Search

0.65	Polypeptide N-acetylgalactosaminyltransferase

0.72	GO:0043413	macromolecule glycosylation
0.72	GO:0009101	glycoprotein biosynthetic process
0.59	GO:0006464	cellular protein modification process
0.40	GO:0009312	oligosaccharide biosynthetic process

0.68	GO:0030246	carbohydrate binding
0.64	GO:0016757	transferase activity, transferring glycosyl groups
0.37	GO:0140096	catalytic activity, acting on a protein
0.32	GO:0046872	metal ion binding

0.72	GO:0000139	Golgi membrane
0.40	GO:0005783	endoplasmic reticulum
0.34	GO:0005795	Golgi stack
0.34	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.64

GO:0016757

tr|T1FQI1|T1FQI1_HELRO
Uncharacterized protein
Search

tr|T1FQI2|T1FQI2_HELRO
Peptidylprolyl isomerase
Search

0.40	Peptidylprolyl isomerase

0.71	GO:0000413	protein peptidyl-prolyl isomerization
0.40	GO:0061077	chaperone-mediated protein folding
0.34	GO:0001933	negative regulation of protein phosphorylation
0.33	GO:0008272	sulfate transport
0.33	GO:0098661	inorganic anion transmembrane transport
0.32	GO:0016570	histone modification

0.71	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.41	GO:0005528	FK506 binding
0.35	GO:0097718	disordered domain specific binding
0.34	GO:0042802	identical protein binding
0.34	GO:0008271	secondary active sulfate transmembrane transporter activity

0.34	GO:0005737	cytoplasm
0.33	GO:0012505	endomembrane system
0.33	GO:0043234	protein complex
0.33	GO:0043231	intracellular membrane-bounded organelle
0.32	GO:0031974	membrane-enclosed lumen
0.32	GO:0043232	intracellular non-membrane-bounded organelle
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.71

EC:5.2.1.8

GO:0003755

tr|T1FQI3|T1FQI3_HELRO
Uncharacterized protein
Search

MYH9

0.61	Myosin heavy chain 9

0.73	GO:0007018	microtubule-based movement
0.57	GO:1903923	positive regulation of protein processing in phagocytic vesicle
0.57	GO:1903919	negative regulation of actin filament severing
0.55	GO:0032796	uropod organization
0.54	GO:0001768	establishment of T cell polarity
0.54	GO:0051295	establishment of meiotic spindle localization
0.54	GO:0006911	phagocytosis, engulfment
0.54	GO:1903131	mononuclear cell differentiation
0.54	GO:0030220	platelet formation
0.53	GO:0043534	blood vessel endothelial cell migration

0.76	GO:0051015	actin filament binding
0.74	GO:0003777	microtubule motor activity
0.73	GO:0008017	microtubule binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0030898	actin-dependent ATPase activity
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0000146	microfilament motor activity
0.53	GO:0043495	protein membrane anchor

0.77	GO:0016459	myosin complex
0.54	GO:0001931	uropod
0.53	GO:0001725	stress fiber
0.53	GO:0001772	immunological synapse
0.52	GO:0032154	cleavage furrow
0.52	GO:0005925	focal adhesion
0.52	GO:0005826	actomyosin contractile ring
0.51	GO:0031594	neuromuscular junction
0.51	GO:0005903	brush border
0.51	GO:0001726	ruffle

0.34

EC:3.6.3.9

GO:0005391

tr|T1FQI4|T1FQI4_HELRO
Uncharacterized protein
Search

tr|T1FQI5|T1FQI5_HELRO
Uncharacterized protein
Search

0.40	Gamma-glutamyltranspeptidase 1

0.79	GO:0006751	glutathione catabolic process
0.61	GO:0006508	proteolysis
0.34	GO:0009416	response to light stimulus
0.33	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:0006805	xenobiotic metabolic process
0.33	GO:0006352	DNA-templated transcription, initiation

0.80	GO:0036374	glutathione hydrolase activity
0.40	GO:0102953	hypoglycin A gamma-glutamyl transpeptidase activity
0.40	GO:0103068	leukotriene C4 gamma-glutamyl transferase activity
0.33	GO:0004930	G-protein coupled receptor activity

0.34	GO:0005669	transcription factor TFIID complex
0.33	GO:0005615	extracellular space
0.33	GO:0000324	fungal-type vacuole
0.30	GO:0016020	membrane

0.80	EC:3.4.19.13	GO:0036374
0.80	KEGG:R00494	GO:0036374

tr|T1FQI6|T1FQI6_HELRO
Uncharacterized protein
Search

0.44	GO:0006338	chromatin remodeling
0.40	GO:2001141	regulation of RNA biosynthetic process
0.40	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.40	GO:0010468	regulation of gene expression
0.35	GO:0030042	actin filament depolymerization
0.34	GO:0006261	DNA-dependent DNA replication
0.33	GO:0016573	histone acetylation
0.32	GO:0006508	proteolysis

0.53	GO:0046872	metal ion binding
0.34	GO:0003779	actin binding
0.34	GO:0004386	helicase activity
0.34	GO:0003682	chromatin binding
0.33	GO:0004402	histone acetyltransferase activity
0.32	GO:0008233	peptidase activity
0.32	GO:0005524	ATP binding

0.54	GO:0005634	nucleus
0.45	GO:0000785	chromatin
0.43	GO:0031974	membrane-enclosed lumen
0.43	GO:1904949	ATPase complex
0.34	GO:0015629	actin cytoskeleton

0.33

GO:0004402

tr|T1FQI7|T1FQI7_HELRO
Uncharacterized protein
Search

0.11	Putative E3 ubiquitin-protein ligase MYCBP2 (Fragment)

0.39	GO:0021785	branchiomotor neuron axon guidance
0.39	GO:0021952	central nervous system projection neuron axonogenesis
0.38	GO:0042177	negative regulation of protein catabolic process
0.37	GO:0051493	regulation of cytoskeleton organization
0.37	GO:0032880	regulation of protein localization
0.35	GO:0016567	protein ubiquitination
0.33	GO:0006351	transcription, DNA-templated
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.62	GO:0016874	ligase activity
0.37	GO:0042803	protein homodimerization activity
0.33	GO:0003676	nucleic acid binding
0.33	GO:0046872	metal ion binding
0.33	GO:0016740	transferase activity

0.38	GO:0030424	axon
0.36	GO:0015630	microtubule cytoskeleton
0.36	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.62

GO:0016874

tr|T1FQI8|T1FQI8_HELRO
Uncharacterized protein
Search

0.53	GO:0007432	salivary gland boundary specification
0.53	GO:2000274	regulation of epithelial cell migration, open tracheal system
0.52	GO:0042685	cardioblast cell fate specification
0.51	GO:0003151	outflow tract morphogenesis
0.50	GO:0008038	neuron recognition
0.50	GO:0048036	central complex development
0.50	GO:0035050	embryonic heart tube development
0.49	GO:0007411	axon guidance
0.49	GO:0007419	ventral cord development
0.49	GO:0008406	gonad development

0.45	GO:0042803	protein homodimerization activity
0.40	GO:0004672	protein kinase activity
0.39	GO:0008201	heparin binding
0.38	GO:0005509	calcium ion binding
0.38	GO:0030554	adenyl nucleotide binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0032555	purine ribonucleotide binding
0.37	GO:0008144	drug binding
0.37	GO:0004872	receptor activity
0.36	GO:0004725	protein tyrosine phosphatase activity

0.49	GO:0030424	axon
0.42	GO:0071666	Slit-Robo signaling complex
0.40	GO:0030426	growth cone
0.39	GO:0043025	neuronal cell body
0.39	GO:0030425	dendrite
0.38	GO:0031982	vesicle
0.35	GO:0043234	protein complex
0.35	GO:0005886	plasma membrane
0.34	GO:0005912	adherens junction
0.34	GO:0045202	synapse

0.36

GO:0004725

tr|T1FQI9|T1FQI9_HELRO
Uncharacterized protein
Search

0.66	GO:0014707	branchiomeric skeletal muscle development
0.64	GO:0060539	diaphragm development
0.62	GO:0060021	palate development
0.59	GO:0072277	metanephric glomerular capillary formation
0.59	GO:0060435	bronchiole development
0.59	GO:0072162	metanephric mesenchymal cell differentiation
0.58	GO:0060426	lung vasculature development
0.58	GO:0000122	negative regulation of transcription by RNA polymerase II
0.57	GO:0060766	negative regulation of androgen receptor signaling pathway
0.56	GO:0048286	lung alveolus development

0.68	GO:0046983	protein dimerization activity
0.61	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.58	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.56	GO:0043425	bHLH transcription factor binding
0.55	GO:0050681	androgen receptor binding
0.54	GO:0042826	histone deacetylase binding
0.54	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.52	GO:0000987	proximal promoter sequence-specific DNA binding
0.50	GO:0001158	enhancer sequence-specific DNA binding
0.50	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding

0.49	GO:0005634	nucleus
0.44	GO:0043233	organelle lumen
0.40	GO:0044446	intracellular organelle part

tr|T1FQJ0|T1FQJ0_HELRO
Uncharacterized protein
Search

IARS2

0.41	Isoleucyl-tRNA synthetase, mitochondrial

0.79	GO:0006428	isoleucyl-tRNA aminoacylation
0.73	GO:0106074	aminoacyl-tRNA metabolism involved in translational fidelity
0.33	GO:0046907	intracellular transport

0.79	GO:0004822	isoleucine-tRNA ligase activity
0.73	GO:0002161	aminoacyl-tRNA editing activity
0.66	GO:0000049	tRNA binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.49	GO:0005737	cytoplasm
0.41	GO:0043231	intracellular membrane-bounded organelle
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0044446	intracellular organelle part

0.79	EC:6.1.1.5	GO:0004822
0.79	KEGG:R03656	GO:0004822

tr|T1FQJ1|T1FQJ1_HELRO
Uncharacterized protein
Search

CDC37

0.82	Hsp90 chaperone protein kinase-targeting subunit

0.48	GO:0098779	positive regulation of mitophagy in response to mitochondrial depolarization
0.48	GO:0060330	regulation of response to interferon-gamma
0.44	GO:0050821	protein stabilization
0.43	GO:0060338	regulation of type I interferon-mediated signaling pathway
0.43	GO:0045859	regulation of protein kinase activity
0.43	GO:0051301	cell division
0.42	GO:0010608	posttranscriptional regulation of gene expression
0.41	GO:0006457	protein folding
0.35	GO:0018108	peptidyl-tyrosine phosphorylation
0.35	GO:0038128	ERBB2 signaling pathway

0.78	GO:0019901	protein kinase binding
0.49	GO:0031072	heat shock protein binding
0.47	GO:0097110	scaffold protein binding
0.44	GO:0019887	protein kinase regulator activity
0.43	GO:0051087	chaperone binding
0.42	GO:0051082	unfolded protein binding
0.35	GO:0004713	protein tyrosine kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.49	GO:1990565	HSP90-CDC37 chaperone complex
0.42	GO:0005829	cytosol
0.34	GO:0070062	extracellular exosome
0.34	GO:0005856	cytoskeleton
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.35

GO:0004713

tr|T1FQJ2|T1FQJ2_HELRO
Cystatin
Search

0.10

Cystatin

0.76

GO:0010951

negative regulation of endopeptidase activity

0.83

GO:0004869

cysteine-type endopeptidase inhibitor activity

tr|T1FQJ3|T1FQJ3_HELRO
Uncharacterized protein
Search

0.58	GO:0006508	proteolysis
0.41	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.35	GO:0006334	nucleosome assembly
0.35	GO:0060997	dendritic spine morphogenesis
0.35	GO:0021952	central nervous system projection neuron axonogenesis
0.34	GO:0070896	positive regulation of transposon integration
0.34	GO:0016348	imaginal disc-derived leg joint morphogenesis
0.34	GO:0018992	germ-line sex determination
0.34	GO:0035017	cuticle pattern formation
0.34	GO:0048067	cuticle pigmentation

0.68	GO:0008234	cysteine-type peptidase activity
0.39	GO:0004930	G-protein coupled receptor activity
0.35	GO:0003723	RNA binding
0.34	GO:0005540	hyaluronic acid binding
0.34	GO:0005509	calcium ion binding
0.34	GO:0005201	extracellular matrix structural constituent
0.33	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0005515	protein binding
0.33	GO:0004521	endoribonuclease activity
0.33	GO:0003677	DNA binding

0.43	GO:0005634	nucleus
0.36	GO:0005886	plasma membrane
0.35	GO:0033165	interphotoreceptor matrix
0.34	GO:0005829	cytosol
0.34	GO:0031974	membrane-enclosed lumen
0.34	GO:0044446	intracellular organelle part
0.33	GO:0005667	transcription factor complex
0.30	GO:0016021	integral component of membrane

0.68	EC:3.4	GO:0008234
0.33	KEGG:R03876	GO:0004842

tr|T1FQJ4|T1FQJ4_HELRO
Uncharacterized protein
Search

0.10	Translocation protein SEC63

0.82	GO:0031204	posttranslational protein targeting to membrane, translocation
0.41	GO:0001889	liver development
0.39	GO:0042552	myelination
0.39	GO:0030968	endoplasmic reticulum unfolded protein response
0.36	GO:0010259	multicellular organism aging
0.36	GO:0072001	renal system development
0.35	GO:0009408	response to heat
0.35	GO:0006457	protein folding
0.35	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.35	GO:0006436	tryptophanyl-tRNA aminoacylation

0.36	GO:0031072	heat shock protein binding
0.36	GO:0051082	unfolded protein binding
0.35	GO:0004830	tryptophan-tRNA ligase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0003677	DNA binding
0.33	GO:0046872	metal ion binding

0.75	GO:0030176	integral component of endoplasmic reticulum membrane
0.33	GO:0005634	nucleus

0.35

EC:6.1.1.2

GO:0004830

tr|T1FQJ5|T1FQJ5_HELRO
Uncharacterized protein
Search

SERBP1

0.89	PAI-1 mRNA-binding protein variant

0.43	GO:0070828	heterochromatin organization
0.42	GO:0016246	RNA interference
0.35	GO:0051567	histone H3-K9 methylation
0.35	GO:0031935	regulation of chromatin silencing
0.34	GO:0042981	regulation of apoptotic process
0.33	GO:0043488	regulation of mRNA stability
0.33	GO:0006414	translational elongation
0.33	GO:1903013	response to differentiation-inducing factor 1
0.33	GO:0043326	chemotaxis to folate
0.33	GO:0043327	chemotaxis to cAMP

0.76	GO:0003730	mRNA 3'-UTR binding
0.47	GO:0045296	cadherin binding
0.34	GO:0004427	inorganic diphosphatase activity
0.33	GO:0000287	magnesium ion binding
0.33	GO:0003746	translation elongation factor activity
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.43	GO:0005829	cytosol
0.43	GO:0005703	polytene chromosome puff
0.43	GO:0005634	nucleus
0.41	GO:0016442	RISC complex
0.35	GO:0005701	polytene chromosome chromocenter
0.34	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0070062	extracellular exosome
0.32	GO:0005886	plasma membrane
0.32	GO:0045335	phagocytic vesicle

0.34	EC:3.6.1.1	GO:0004427
0.34	KEGG:R00004	GO:0004427

tr|T1FQJ6|T1FQJ6_HELRO
Uncharacterized protein
Search

tr|T1FQJ7|T1FQJ7_HELRO
Uncharacterized protein
Search

0.77	GO:1903363	negative regulation of cellular protein catabolic process
0.77	GO:0042147	retrograde transport, endosome to Golgi
0.71	GO:0043087	regulation of GTPase activity
0.68	GO:0051345	positive regulation of hydrolase activity
0.53	GO:0006886	intracellular protein transport

0.80

GO:0017112

Rab guanyl-nucleotide exchange factor activity

0.85	GO:0034066	RIC1-RGP1 guanyl-nucleotide exchange factor complex
0.65	GO:0005829	cytosol
0.56	GO:0000139	Golgi membrane
0.38	GO:0005802	trans-Golgi network
0.30	GO:0031224	intrinsic component of membrane

tr|T1FQJ8|T1FQJ8_HELRO
Uncharacterized protein
Search

tr|T1FQJ9|T1FQJ9_HELRO
Uncharacterized protein
Search

CDCA7

0.62	Cell division cycle-associated protein 7

0.74	GO:0042127	regulation of cell proliferation
0.57	GO:0048522	positive regulation of cellular process
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.55	GO:0051301	cell division
0.35	GO:0006915	apoptotic process
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation
0.34	GO:0048538	thymus development
0.34	GO:0043405	regulation of MAP kinase activity

0.34	GO:0004709	MAP kinase kinase kinase activity
0.33	GO:0005515	protein binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003677	DNA binding
0.32	GO:0008168	methyltransferase activity

0.46	GO:0005829	cytosol
0.46	GO:0031981	nuclear lumen
0.38	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

0.34

EC:2.7.11 EC:2.7.11.25

GO:0004709

tr|T1FQK0|T1FQK0_HELRO
Uncharacterized protein
Search

tr|T1FQK1|T1FQK1_HELRO
Uncharacterized protein
Search

0.48	GO:0006397	mRNA processing
0.42	GO:0016310	phosphorylation

0.43	GO:0003723	RNA binding
0.43	GO:0016301	kinase activity
0.41	GO:0004386	helicase activity
0.38	GO:0008270	zinc ion binding
0.37	GO:0030554	adenyl nucleotide binding
0.37	GO:0097367	carbohydrate derivative binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding

0.44	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

tr|T1FQK2|T1FQK2_HELRO
Uncharacterized protein
Search

tr|T1FQK3|T1FQK3_HELRO
Uncharacterized protein
Search

tr|T1FQK4|T1FQK4_HELRO
Uncharacterized protein
Search

tr|T1FQK5|T1FQK5_HELRO
Uncharacterized protein
Search

tr|T1FQK6|T1FQK6_HELRO
Uncharacterized protein
Search

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.48	GO:0051606	detection of stimulus
0.48	GO:0007600	sensory perception
0.43	GO:0042221	response to chemical
0.40	GO:0007631	feeding behavior
0.37	GO:0007268	chemical synaptic transmission
0.36	GO:0009416	response to light stimulus
0.36	GO:0018298	protein-chromophore linkage
0.36	GO:0009605	response to external stimulus
0.34	GO:0006955	immune response

0.72	GO:0004930	G-protein coupled receptor activity
0.50	GO:0001653	peptide receptor activity
0.48	GO:0004984	olfactory receptor activity
0.36	GO:0016500	protein-hormone receptor activity
0.36	GO:0009881	photoreceptor activity
0.35	GO:0004896	cytokine receptor activity
0.35	GO:0005549	odorant binding
0.35	GO:0004180	carboxypeptidase activity

0.40	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1FQK7|T1FQK7_HELRO
Uncharacterized protein
Search

tr|T1FQK8|T1FQK8_HELRO
Uncharacterized protein
Search

tr|T1FQK9|T1FQK9_HELRO
Uncharacterized protein
Search

tr|T1FQL0|T1FQL0_HELRO
Uncharacterized protein
Search

PDPK1

0.44	3-phosphoinositide-dependent protein kinase 1

0.63	GO:0006468	protein phosphorylation
0.40	GO:0051124	synaptic growth at neuromuscular junction
0.40	GO:0045793	positive regulation of cell size
0.39	GO:0051239	regulation of multicellular organismal process
0.39	GO:0043066	negative regulation of apoptotic process
0.39	GO:1901700	response to oxygen-containing compound
0.39	GO:0010033	response to organic substance
0.39	GO:0007166	cell surface receptor signaling pathway
0.39	GO:1905564	positive regulation of vascular endothelial cell proliferation
0.38	GO:0048638	regulation of developmental growth

0.64	GO:0004672	protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0032555	purine ribonucleotide binding
0.39	GO:0016004	phospholipase activator activity
0.39	GO:0043274	phospholipase binding

0.39	GO:0031594	neuromuscular junction
0.35	GO:0042995	cell projection
0.35	GO:0014069	postsynaptic density
0.34	GO:0031410	cytoplasmic vesicle
0.34	GO:0005886	plasma membrane
0.33	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

tr|T1FQL1|T1FQL1_HELRO
Uncharacterized protein
Search

tr|T1FQL2|T1FQL2_HELRO
Uncharacterized protein
Search

0.64	Epidermal growth factor receptor pathway substrate 15-like 1a

0.44	GO:0006895	Golgi to endosome transport
0.43	GO:0048268	clathrin coat assembly
0.41	GO:0006897	endocytosis
0.40	GO:1902579	multi-organism localization
0.40	GO:0051806	entry into cell of other organism involved in symbiotic interaction
0.40	GO:0044409	entry into host
0.39	GO:0019058	viral life cycle
0.37	GO:0001921	positive regulation of receptor recycling
0.36	GO:0032456	endocytic recycling
0.35	GO:0042127	regulation of cell proliferation

0.68	GO:0005509	calcium ion binding
0.46	GO:0045296	cadherin binding
0.44	GO:0031593	polyubiquitin modification-dependent protein binding
0.41	GO:0042802	identical protein binding
0.34	GO:0051082	unfolded protein binding
0.34	GO:0017124	SH3 domain binding

0.46	GO:0030132	clathrin coat of coated pit
0.44	GO:0016235	aggresome
0.44	GO:0060170	ciliary membrane
0.44	GO:0030128	clathrin coat of endocytic vesicle
0.42	GO:0030131	clathrin adaptor complex
0.40	GO:0005829	cytosol
0.37	GO:0043231	intracellular membrane-bounded organelle
0.37	GO:0009925	basal plasma membrane
0.36	GO:0016324	apical plasma membrane
0.36	GO:0005769	early endosome

tr|T1FQL3|T1FQL3_HELRO
Uncharacterized protein
Search

DIS3

0.90	DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease

0.62	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.61	GO:0071034	CUT catabolic process
0.56	GO:0016075	rRNA catabolic process
0.49	GO:0065009	regulation of molecular function
0.49	GO:0071027	nuclear RNA surveillance
0.46	GO:0006364	rRNA processing
0.46	GO:0051607	defense response to virus
0.45	GO:0000278	mitotic cell cycle
0.39	GO:0060255	regulation of macromolecule metabolic process
0.34	GO:0031329	regulation of cellular catabolic process

0.67	GO:0004527	exonuclease activity
0.57	GO:0004540	ribonuclease activity
0.54	GO:0005085	guanyl-nucleotide exchange factor activity
0.54	GO:0004519	endonuclease activity
0.34	GO:0003723	RNA binding
0.34	GO:0003678	DNA helicase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.64	GO:0000176	nuclear exosome (RNase complex)
0.51	GO:0005654	nucleoplasm
0.51	GO:0005829	cytosol
0.50	GO:0005652	nuclear lamina
0.38	GO:0005730	nucleolus
0.30	GO:0016020	membrane

tr|T1FQL4|T1FQL4_HELRO
Uncharacterized protein
Search

0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.73	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.61	GO:0023014	signal transduction by protein phosphorylation
0.58	GO:0035556	intracellular signal transduction
0.48	GO:0009880	embryonic pattern specification
0.48	GO:0048863	stem cell differentiation
0.47	GO:0001667	ameboidal-type cell migration
0.47	GO:0010721	negative regulation of cell development
0.47	GO:0061026	cardiac muscle tissue regeneration
0.47	GO:0045165	cell fate commitment

0.79	GO:0004716	signal transducer, downstream of receptor, with protein tyrosine kinase activity
0.78	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.46	GO:0005154	epidermal growth factor receptor binding
0.42	GO:0044212	transcription regulatory region DNA binding
0.42	GO:0042803	protein homodimerization activity
0.34	GO:0038132	neuregulin binding

0.44	GO:0016323	basolateral plasma membrane
0.43	GO:0043235	receptor complex
0.43	GO:0005622	intracellular
0.43	GO:0035230	cytoneme
0.37	GO:0043227	membrane-bounded organelle
0.33	GO:0005901	caveola
0.33	GO:0014069	postsynaptic density
0.32	GO:0031974	membrane-enclosed lumen
0.32	GO:0005576	extracellular region
0.32	GO:0044422	organelle part

0.79	EC:2.7.10	GO:0004716
0.34	KEGG:R04545	GO:0046934

tr|T1FQL5|T1FQL5_HELRO
Uncharacterized protein
Search

tr|T1FQL6|T1FQL6_HELRO
Uncharacterized protein
Search

tr|T1FQL7|T1FQL7_HELRO
Uncharacterized protein
Search

tr|T1FQL8|T1FQL8_HELRO
Uncharacterized protein
Search

tr|T1FQL9|T1FQL9_HELRO
Transporter
Search

0.49	Transporter

0.75	GO:0006836	neurotransmitter transport
0.55	GO:0055085	transmembrane transport
0.43	GO:0009636	response to toxic substance
0.41	GO:1903346	positive regulation of protein polyglycylation
0.40	GO:0043092	L-amino acid import
0.39	GO:0030317	flagellated sperm motility
0.38	GO:0015804	neutral amino acid transport
0.38	GO:0006520	cellular amino acid metabolic process
0.37	GO:0015893	drug transport
0.36	GO:0006812	cation transport

0.78	GO:0005328	neurotransmitter:sodium symporter activity
0.40	GO:0015187	glycine transmembrane transporter activity
0.35	GO:0005034	osmosensor activity
0.34	GO:0009881	photoreceptor activity
0.34	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity
0.34	GO:0005283	sodium:amino acid symporter activity
0.34	GO:0015296	anion:cation symporter activity

0.43	GO:0005887	integral component of plasma membrane
0.37	GO:0031526	brush border membrane
0.34	GO:0070062	extracellular exosome

tr|T1FQM0|T1FQM0_HELRO
Mannosyltransferase
Search

0.24	Mannosyltransferase

0.42	GO:0006506	GPI anchor biosynthetic process
0.42	GO:0097502	mannosylation
0.34	GO:0006281	DNA repair

0.65	GO:0016757	transferase activity, transferring glycosyl groups
0.34	GO:0008094	DNA-dependent ATPase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0003677	DNA binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.72	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

0.65

GO:0016757

tr|T1FQM1|T1FQM1_HELRO
Uncharacterized protein
Search

0.44	GO:1903690	negative regulation of wound healing, spreading of epidermal cells
0.44	GO:1904259	regulation of basement membrane assembly involved in embryonic body morphogenesis
0.44	GO:0090091	positive regulation of extracellular matrix disassembly
0.43	GO:1901203	positive regulation of extracellular matrix assembly
0.43	GO:0030953	astral microtubule organization
0.43	GO:0051497	negative regulation of stress fiber assembly
0.43	GO:0010458	exit from mitosis
0.43	GO:0007026	negative regulation of microtubule depolymerization
0.43	GO:0040019	positive regulation of embryonic development
0.42	GO:0010470	regulation of gastrulation

0.85	GO:0043515	kinetochore binding
0.85	GO:0051010	microtubule plus-end binding
0.43	GO:0002162	dystroglycan binding

0.85	GO:0005828	kinetochore microtubule
0.83	GO:0005881	cytoplasmic microtubule
0.44	GO:0031592	centrosomal corona
0.43	GO:0045180	basal cortex
0.43	GO:0030981	cortical microtubule cytoskeleton
0.41	GO:0005925	focal adhesion
0.41	GO:0000776	kinetochore
0.39	GO:0005794	Golgi apparatus
0.37	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

tr|T1FQM2|T1FQM2_HELRO
Uncharacterized protein
Search

tr|T1FQM3|T1FQM3_HELRO
Uncharacterized protein
Search

0.63	GO:0006468	protein phosphorylation
0.60	GO:0035556	intracellular signal transduction
0.54	GO:0007426	tracheal outgrowth, open tracheal system
0.52	GO:0007476	imaginal disc-derived wing morphogenesis
0.43	GO:0008293	torso signaling pathway
0.42	GO:0007351	tripartite regional subdivision
0.42	GO:0043410	positive regulation of MAPK cascade
0.42	GO:0046579	positive regulation of Ras protein signal transduction
0.42	GO:0000578	embryonic axis specification
0.42	GO:0009948	anterior/posterior axis specification

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0046872	metal ion binding
0.37	GO:0004871	signal transducer activity

0.44	GO:0005622	intracellular
0.33	GO:0005886	plasma membrane
0.32	GO:0012505	endomembrane system
0.31	GO:0043227	membrane-bounded organelle

tr|T1FQM4|T1FQM4_HELRO
Uncharacterized protein
Search

tr|T1FQM5|T1FQM5_HELRO
Uncharacterized protein
Search

tr|T1FQM6|T1FQM6_HELRO
Uncharacterized protein
Search

tr|T1FQM7|T1FQM7_HELRO
Uncharacterized protein
Search

0.62	GO:0006468	protein phosphorylation
0.41	GO:0018210	peptidyl-threonine modification
0.40	GO:0018209	peptidyl-serine modification
0.38	GO:0007165	signal transduction
0.37	GO:0035023	regulation of Rho protein signal transduction
0.35	GO:0065009	regulation of molecular function
0.35	GO:0006915	apoptotic process
0.34	GO:0018212	peptidyl-tyrosine modification

0.63	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.36	GO:0005509	calcium ion binding
0.34	GO:0016775	phosphotransferase activity, nitrogenous group as acceptor
0.34	GO:0038023	signaling receptor activity
0.32	GO:0003676	nucleic acid binding

0.34	GO:0005622	intracellular
0.30	GO:0016020	membrane

0.34

GO:0016775

tr|T1FQM8|T1FQM8_HELRO
Uncharacterized protein
Search

tr|T1FQM9|T1FQM9_HELRO
Uncharacterized protein
Search

tr|T1FQN0|T1FQN0_HELRO
Uncharacterized protein
Search

tr|T1FQN1|T1FQN1_HELRO
Uncharacterized protein
Search

tr|T1FQN2|T1FQN2_HELRO
Uncharacterized protein
Search

tr|T1FQN3|T1FQN3_HELRO
Uncharacterized protein
Search

0.56	Poly(A) RNA polymerase GLD2

0.64	GO:0071044	histone mRNA catabolic process
0.61	GO:0002244	hematopoietic progenitor cell differentiation
0.60	GO:0043631	RNA polyadenylation
0.48	GO:0007616	long-term memory
0.43	GO:1990603	dark adaptation
0.42	GO:0006397	mRNA processing
0.40	GO:0021766	hippocampus development
0.40	GO:0060041	retina development in camera-type eye
0.39	GO:0030182	neuron differentiation
0.38	GO:0048477	oogenesis

0.63	GO:0004652	polynucleotide adenylyltransferase activity
0.38	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0046872	metal ion binding
0.37	GO:0005515	protein binding
0.33	GO:0003723	RNA binding
0.33	GO:0030983	mismatched DNA binding
0.32	GO:0003700	DNA binding transcription factor activity

0.50	GO:0005634	nucleus
0.45	GO:0043005	neuron projection
0.42	GO:0043233	organelle lumen
0.39	GO:0044446	intracellular organelle part
0.38	GO:0005737	cytoplasm
0.37	GO:0031379	RNA-directed RNA polymerase complex
0.32	GO:0012505	endomembrane system
0.32	GO:0071944	cell periphery
0.30	GO:0016020	membrane

0.63

EC:2.7.7.19

GO:0004652

tr|T1FQN4|T1FQN4_HELRO
Uncharacterized protein
Search

tr|T1FQN5|T1FQN5_HELRO
Uncharacterized protein
Search

0.51	GO:0043044	ATP-dependent chromatin remodeling
0.45	GO:0031047	gene silencing by RNA
0.44	GO:0007162	negative regulation of cell adhesion
0.43	GO:0006888	ER to Golgi vesicle-mediated transport
0.42	GO:0031050	dsRNA fragmentation
0.41	GO:0016441	posttranscriptional gene silencing
0.41	GO:0006886	intracellular protein transport
0.40	GO:0017148	negative regulation of translation
0.39	GO:0043547	positive regulation of GTPase activity
0.39	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic

0.42	GO:0003676	nucleic acid binding
0.41	GO:0045735	nutrient reservoir activity
0.40	GO:0032296	double-stranded RNA-specific ribonuclease activity
0.40	GO:0019104	DNA N-glycosylase activity
0.40	GO:0003712	transcription cofactor activity
0.39	GO:0005096	GTPase activator activity
0.39	GO:0004252	serine-type endopeptidase activity
0.39	GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters
0.37	GO:0016887	ATPase activity
0.37	GO:0046872	metal ion binding

0.47	GO:0016514	SWI/SNF complex
0.44	GO:0030127	COPII vesicle coat
0.41	GO:0000124	SAGA complex
0.37	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.40

EC:3.2.2

GO:0019104

tr|T1FQN6|T1FQN6_HELRO
Uncharacterized protein
Search

0.43	GO:0007426	tracheal outgrowth, open tracheal system
0.42	GO:0006888	ER to Golgi vesicle-mediated transport
0.42	GO:0065007	biological regulation
0.41	GO:0007476	imaginal disc-derived wing morphogenesis
0.40	GO:0006886	intracellular protein transport
0.39	GO:0051716	cellular response to stimulus
0.38	GO:0010033	response to organic substance
0.38	GO:0023052	signaling
0.38	GO:0007154	cell communication
0.37	GO:0071041	antisense RNA transcript catabolic process

0.43	GO:0003676	nucleic acid binding
0.40	GO:0140110	transcription regulator activity
0.39	GO:0008270	zinc ion binding
0.39	GO:0004674	protein serine/threonine kinase activity
0.38	GO:0030554	adenyl nucleotide binding
0.38	GO:0097367	carbohydrate derivative binding
0.38	GO:0008144	drug binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0050825	ice binding
0.37	GO:0005515	protein binding

0.44	GO:0005634	nucleus
0.43	GO:0030127	COPII vesicle coat
0.37	GO:0005929	cilium
0.37	GO:0005765	lysosomal membrane
0.37	GO:0035649	Nrd1 complex
0.37	GO:0005856	cytoskeleton
0.37	GO:1902494	catalytic complex
0.36	GO:0070013	intracellular organelle lumen
0.36	GO:0032838	plasma membrane bounded cell projection cytoplasm
0.35	GO:0000785	chromatin

0.39

GO:0004674

tr|T1FQN7|T1FQN7_HELRO
Uncharacterized protein
Search

0.40	GO:1903506	regulation of nucleic acid-templated transcription
0.40	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.40	GO:0010468	regulation of gene expression
0.34	GO:0006351	transcription, DNA-templated
0.34	GO:0008298	intracellular mRNA localization
0.34	GO:0051646	mitochondrion localization
0.33	GO:0007005	mitochondrion organization
0.33	GO:0006401	RNA catabolic process
0.33	GO:0016071	mRNA metabolic process
0.33	GO:0010605	negative regulation of macromolecule metabolic process

0.51	GO:0003676	nucleic acid binding
0.38	GO:0046872	metal ion binding
0.35	GO:0140110	transcription regulator activity

0.36	GO:0005634	nucleus
0.34	GO:0032473	cytoplasmic side of mitochondrial outer membrane
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

tr|T1FQN8|T1FQN8_HELRO
Uncharacterized protein
Search

0.50	GO:0007155	cell adhesion
0.41	GO:0035335	peptidyl-tyrosine dephosphorylation
0.41	GO:0031104	dendrite regeneration
0.40	GO:0048678	response to axon injury
0.40	GO:0008347	glial cell migration
0.39	GO:0001764	neuron migration
0.39	GO:0007411	axon guidance
0.35	GO:0006979	response to oxidative stress
0.35	GO:0098869	cellular oxidant detoxification
0.35	GO:0006898	receptor-mediated endocytosis

0.56	GO:0005540	hyaluronic acid binding
0.51	GO:0005509	calcium ion binding
0.41	GO:0004725	protein tyrosine phosphatase activity
0.39	GO:0005201	extracellular matrix structural constituent
0.36	GO:0005044	scavenger receptor activity
0.36	GO:0008146	sulfotransferase activity
0.36	GO:0004601	peroxidase activity
0.34	GO:0020037	heme binding

0.41	GO:0005578	proteinaceous extracellular matrix
0.39	GO:0044420	extracellular matrix component
0.38	GO:0005615	extracellular space
0.30	GO:0016020	membrane

0.41	EC:3.1.3.48	GO:0004725
0.36	KEGG:R03532	GO:0004601

tr|T1FQN9|T1FQN9_HELRO
Uncharacterized protein
Search

0.46	GO:0030198	extracellular matrix organization
0.44	GO:0006508	proteolysis
0.43	GO:0006030	chitin metabolic process
0.42	GO:1900047	negative regulation of hemostasis
0.42	GO:0050819	negative regulation of coagulation
0.42	GO:0061045	negative regulation of wound healing
0.41	GO:0030193	regulation of blood coagulation
0.41	GO:0035122	embryonic medial fin morphogenesis
0.40	GO:0090092	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
0.40	GO:0090287	regulation of cellular response to growth factor stimulus

0.70	GO:0005509	calcium ion binding
0.49	GO:0005201	extracellular matrix structural constituent
0.49	GO:0004222	metalloendopeptidase activity
0.44	GO:0008270	zinc ion binding
0.43	GO:0008061	chitin binding
0.38	GO:0016504	peptidase activator activity
0.36	GO:0005178	integrin binding
0.35	GO:0008201	heparin binding
0.34	GO:0042802	identical protein binding
0.34	GO:0004888	transmembrane signaling receptor activity

0.53	GO:0005576	extracellular region
0.36	GO:0099512	supramolecular fiber
0.33	GO:0005737	cytoplasm
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.49

GO:0004222

tr|T1FQP0|T1FQP0_HELRO
Uncharacterized protein
Search

0.47	GO:0016042	lipid catabolic process
0.43	GO:1903506	regulation of nucleic acid-templated transcription
0.43	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.43	GO:0010468	regulation of gene expression
0.38	GO:0030953	astral microtubule organization
0.37	GO:0002128	tRNA nucleoside ribose methylation
0.37	GO:0009107	lipoate biosynthetic process
0.37	GO:0009249	protein lipoylation
0.37	GO:0002181	cytoplasmic translation
0.37	GO:0034508	centromere complex assembly

0.46	GO:0003723	RNA binding
0.44	GO:0003700	DNA binding transcription factor activity
0.40	GO:0016787	hydrolase activity
0.37	GO:0016992	lipoate synthase activity
0.37	GO:0005515	protein binding
0.37	GO:0098772	molecular function regulator
0.36	GO:0008175	tRNA methyltransferase activity
0.36	GO:0051539	4 iron, 4 sulfur cluster binding
0.35	GO:0003677	DNA binding
0.35	GO:0044877	macromolecular complex binding

0.38	GO:0031592	centrosomal corona
0.38	GO:0020011	apicoplast
0.36	GO:0005634	nucleus
0.34	GO:0005694	chromosome
0.34	GO:0043233	organelle lumen
0.33	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.40

GO:0016787

tr|T1FQP1|T1FQP1_HELRO
Uncharacterized protein
Search

tr|T1FQP2|T1FQP2_HELRO
Uncharacterized protein
Search

tr|T1FQP3|T1FQP3_HELRO
Uncharacterized protein
Search

tr|T1FQP4|T1FQP4_HELRO
Hexosyltransferase
Search

0.21	Hexosyltransferase

0.74	GO:0006486	protein glycosylation
0.57	GO:0006682	galactosylceramide biosynthetic process
0.51	GO:0030259	lipid glycosylation
0.48	GO:0009312	oligosaccharide biosynthetic process

0.81	GO:0008378	galactosyltransferase activity
0.49	GO:0008194	UDP-glycosyltransferase activity

0.74	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

0.81

GO:0008378

tr|T1FQP5|T1FQP5_HELRO
Uncharacterized protein
Search

tr|T1FQP6|T1FQP6_HELRO
Phosphate transporter
Search

0.22	Phosphate transporter

0.73	GO:0006817	phosphate ion transport
0.54	GO:0055085	transmembrane transport
0.41	GO:0006814	sodium ion transport

0.74	GO:0005315	inorganic phosphate transmembrane transporter activity
0.45	GO:0015319	sodium:inorganic phosphate symporter activity

0.40

GO:0005887

integral component of plasma membrane

tr|T1FQP7|T1FQP7_HELRO
Uncharacterized protein
Search

tr|T1FQP8|T1FQP8_HELRO
Uncharacterized protein
Search

tr|T1FQP9|T1FQP9_HELRO
Uncharacterized protein
Search

tr|T1FQQ0|T1FQQ0_HELRO
Uncharacterized protein
Search

0.52	GO:0007186	G-protein coupled receptor signaling pathway
0.41	GO:0033554	cellular response to stress
0.40	GO:0036211	protein modification process
0.40	GO:0010604	positive regulation of macromolecule metabolic process
0.40	GO:0051173	positive regulation of nitrogen compound metabolic process
0.40	GO:0048522	positive regulation of cellular process
0.39	GO:0006357	regulation of transcription by RNA polymerase II
0.39	GO:0044267	cellular protein metabolic process
0.39	GO:0009891	positive regulation of biosynthetic process
0.39	GO:0090305	nucleic acid phosphodiester bond hydrolysis

0.52	GO:0004930	G-protein coupled receptor activity
0.39	GO:0005515	protein binding
0.39	GO:0016788	hydrolase activity, acting on ester bonds
0.39	GO:0140096	catalytic activity, acting on a protein
0.39	GO:0046872	metal ion binding
0.38	GO:0016301	kinase activity
0.38	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.38	GO:0003676	nucleic acid binding
0.38	GO:0097367	carbohydrate derivative binding
0.38	GO:0017076	purine nucleotide binding

0.44	GO:0005634	nucleus
0.38	GO:0070013	intracellular organelle lumen
0.38	GO:0044446	intracellular organelle part
0.38	GO:0005694	chromosome
0.37	GO:0032991	macromolecular complex
0.36	GO:0005829	cytosol
0.35	GO:0012505	endomembrane system
0.35	GO:0005773	vacuole
0.34	GO:0044448	cell cortex part
0.34	GO:0098805	whole membrane

0.39

GO:0016788

tr|T1FQQ1|T1FQQ1_HELRO
Uncharacterized protein
Search

0.70	Upstream activation factor subunit spp27

0.43	GO:0090304	nucleic acid metabolic process
0.42	GO:0044085	cellular component biogenesis
0.42	GO:0071824	protein-DNA complex subunit organization
0.41	GO:0010467	gene expression
0.40	GO:0031498	chromatin disassembly
0.40	GO:0071103	DNA conformation change
0.39	GO:0051304	chromosome separation
0.39	GO:0006359	regulation of transcription by RNA polymerase III
0.39	GO:0016573	histone acetylation
0.38	GO:0032984	macromolecular complex disassembly

0.46	GO:0005509	calcium ion binding
0.42	GO:0016788	hydrolase activity, acting on ester bonds
0.41	GO:0003676	nucleic acid binding
0.40	GO:0003756	protein disulfide isomerase activity
0.40	GO:0005515	protein binding
0.39	GO:0001026	TFIIIB-type transcription factor activity
0.39	GO:0004650	polygalacturonase activity
0.38	GO:0003917	DNA topoisomerase type I activity
0.38	GO:0008270	zinc ion binding
0.38	GO:0017111	nucleoside-triphosphatase activity

0.46	GO:0034457	Mpp10 complex
0.45	GO:0005732	small nucleolar ribonucleoprotein complex
0.43	GO:0044798	nuclear transcription factor complex
0.42	GO:0019013	viral nucleocapsid
0.41	GO:0016591	DNA-directed RNA polymerase II, holoenzyme
0.38	GO:0005783	endoplasmic reticulum
0.37	GO:0005694	chromosome
0.37	GO:0005829	cytosol
0.36	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.42

GO:0016788

tr|T1FQQ2|T1FQQ2_HELRO
Uncharacterized protein
Search

tr|T1FQQ3|T1FQQ3_HELRO
Uncharacterized protein
Search

tr|T1FQQ4|T1FQQ4_HELRO
Uncharacterized protein
Search

0.55	Cytoskeletal beta-actin

0.43	GO:1904000	positive regulation of eating behavior
0.42	GO:0030536	larval feeding behavior
0.42	GO:0030033	microvillus assembly
0.41	GO:0002119	nematode larval development
0.40	GO:0035148	tube formation
0.36	GO:0072749	cellular response to cytochalasin B
0.36	GO:0098974	postsynaptic actin cytoskeleton organization
0.35	GO:0000916	actomyosin contractile ring contraction
0.35	GO:0000011	vacuole inheritance
0.35	GO:1903475	mitotic actomyosin contractile ring assembly

0.52	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0098973	structural constituent of postsynaptic actin cytoskeleton
0.36	GO:0030957	Tat protein binding
0.36	GO:0042802	identical protein binding
0.36	GO:0050998	nitric-oxide synthase binding
0.35	GO:0019894	kinesin binding
0.35	GO:0004402	histone acetyltransferase activity
0.34	GO:0019901	protein kinase binding

0.43	GO:0097516	microvillar actin bundle
0.42	GO:1990357	terminal web
0.40	GO:0097433	dense body
0.39	GO:0005925	focal adhesion
0.36	GO:0035267	NuA4 histone acetyltransferase complex
0.36	GO:0120106	actomyosin contractile ring, distal actin filament layer
0.35	GO:0120104	actomyosin contractile ring, proximal layer
0.35	GO:0000142	cellular bud neck contractile ring
0.35	GO:0120105	actomyosin contractile ring, intermediate layer
0.35	GO:0000812	Swr1 complex

0.35

GO:0004402

tr|T1FQQ5|T1FQQ5_HELRO
Uncharacterized protein
Search

0.95	Putative beta amyloid-binding protein

0.71	GO:0072657	protein localization to membrane
0.56	GO:1905852	positive regulation of backward locomotion
0.55	GO:1902946	protein localization to early endosome
0.54	GO:0040026	positive regulation of vulval development
0.53	GO:0050975	sensory perception of touch
0.53	GO:0007270	neuron-neuron synaptic transmission
0.52	GO:0097120	receptor localization to synapse
0.51	GO:0009612	response to mechanical stimulus
0.50	GO:1990778	protein localization to cell periphery
0.41	GO:0006468	protein phosphorylation

0.50	GO:0017137	Rab GTPase binding
0.41	GO:0004672	protein kinase activity
0.38	GO:0032559	adenyl ribonucleotide binding
0.38	GO:0008144	drug binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding

0.53	GO:0000138	Golgi trans cisterna
0.50	GO:0030140	trans-Golgi network transport vesicle
0.50	GO:0043025	neuronal cell body
0.50	GO:0030425	dendrite
0.48	GO:0045202	synapse
0.42	GO:0032580	Golgi cisterna membrane
0.40	GO:0030054	cell junction
0.40	GO:0005886	plasma membrane

tr|T1FQQ6|T1FQQ6_HELRO
Uncharacterized protein
Search

tr|T1FQQ7|T1FQQ7_HELRO
Uncharacterized protein
Search

tr|T1FQQ8|T1FQQ8_HELRO
Uncharacterized protein
Search

0.73	GO:0043547	positive regulation of GTPase activity
0.59	GO:0007165	signal transduction
0.52	GO:0060101	negative regulation of phagocytosis, engulfment
0.50	GO:0070587	regulation of cell-cell adhesion involved in gastrulation
0.48	GO:0030336	negative regulation of cell migration
0.46	GO:0022409	positive regulation of cell-cell adhesion
0.39	GO:0030833	regulation of actin filament polymerization

0.73	GO:0005096	GTPase activator activity
0.50	GO:0048365	Rac GTPase binding
0.49	GO:0043621	protein self-association
0.32	GO:0016740	transferase activity

0.48	GO:0016342	catenin complex
0.47	GO:0005912	adherens junction
0.45	GO:0005938	cell cortex
0.40	GO:0055037	recycling endosome
0.30	GO:0016021	integral component of membrane

0.32

GO:0016740

tr|T1FQQ9|T1FQQ9_HELRO
Uncharacterized protein
Search

0.45	GO:0007165	signal transduction
0.44	GO:0006030	chitin metabolic process
0.42	GO:0005975	carbohydrate metabolic process
0.41	GO:0010951	negative regulation of endopeptidase activity
0.41	GO:1902358	sulfate transmembrane transport
0.40	GO:0046939	nucleotide phosphorylation
0.36	GO:0055114	oxidation-reduction process

0.45	GO:0030246	carbohydrate binding
0.44	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.44	GO:0008061	chitin binding
0.42	GO:0004867	serine-type endopeptidase inhibitor activity
0.42	GO:0001871	pattern binding
0.42	GO:0004017	adenylate kinase activity
0.42	GO:0008271	secondary active sulfate transmembrane transporter activity
0.37	GO:0016491	oxidoreductase activity
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding

0.41	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.44

GO:0004553

tr|T1FQR0|T1FQR0_HELRO
Phosphoinositide phospholipase C
Search

0.25	Phosphoinositide phospholipase C

0.72	GO:0016042	lipid catabolic process
0.63	GO:0035556	intracellular signal transduction
0.43	GO:0003073	regulation of systemic arterial blood pressure
0.36	GO:0007420	brain development
0.36	GO:0051726	regulation of cell cycle

0.82	GO:0004435	phosphatidylinositol phospholipase C activity
0.67	GO:0005509	calcium ion binding
0.63	GO:0004871	signal transducer activity
0.42	GO:0045296	cadherin binding
0.41	GO:0005516	calmodulin binding

0.45	GO:0005622	intracellular
0.39	GO:0043233	organelle lumen
0.37	GO:0043234	protein complex
0.37	GO:0043227	membrane-bounded organelle

0.82	EC:3.1.4.11	GO:0004435
0.82	KEGG:R03435	GO:0004435

tr|T1FQR1|T1FQR1_HELRO
Uncharacterized protein
Search

tr|T1FQR2|T1FQR2_HELRO
Uncharacterized protein
Search

0.59	GO:0019371	cyclooxygenase pathway
0.56	GO:0008217	regulation of blood pressure
0.54	GO:0006954	inflammatory response
0.50	GO:0006979	response to oxidative stress
0.49	GO:0098869	cellular oxidant detoxification
0.46	GO:0010466	negative regulation of peptidase activity
0.45	GO:0052548	regulation of endopeptidase activity
0.44	GO:0007219	Notch signaling pathway
0.44	GO:0007275	multicellular organism development
0.42	GO:0030154	cell differentiation

0.62	GO:0005509	calcium ion binding
0.59	GO:0004666	prostaglandin-endoperoxide synthase activity
0.50	GO:0004601	peroxidase activity
0.46	GO:0046906	tetrapyrrole binding
0.44	GO:0030414	peptidase inhibitor activity
0.43	GO:0061135	endopeptidase regulator activity
0.43	GO:0048037	cofactor binding
0.38	GO:0042803	protein homodimerization activity
0.38	GO:0005112	Notch binding
0.38	GO:0019899	enzyme binding

0.46	GO:0005581	collagen trimer
0.39	GO:0120025	plasma membrane bounded cell projection
0.39	GO:0097458	neuron part
0.38	GO:0005783	endoplasmic reticulum
0.36	GO:0005576	extracellular region
0.35	GO:0005886	plasma membrane
0.35	GO:0043202	lysosomal lumen
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0005903	brush border
0.34	GO:0031090	organelle membrane

0.59	EC:1.14.99.1	GO:0004666
0.50	KEGG:R03532	GO:0004601

tr|T1FQR3|T1FQR3_HELRO
Uncharacterized protein
Search

tr|T1FQR4|T1FQR4_HELRO
Uncharacterized protein
Search

0.92	Mitochondrial ATP synthase subunit g

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.36	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.32	GO:0055114	oxidation-reduction process

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.37	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
0.36	GO:0019829	cation-transporting ATPase activity
0.34	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen

0.78	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
0.30	GO:0016021	integral component of membrane

0.34

EC:1.13.11

GO:0016702

tr|T1FQR5|T1FQR5_HELRO
Uncharacterized protein
Search

tr|T1FQR6|T1FQR6_HELRO
Uncharacterized protein
Search

0.61	SREK1-interacting protein 1

0.34

GO:0019991

septate junction assembly

0.62	GO:0008270	zinc ion binding
0.50	GO:0003676	nucleic acid binding
0.34	GO:0005509	calcium ion binding

0.34	GO:0005918	septate junction
0.34	GO:0005634	nucleus
0.33	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

tr|T1FQR7|T1FQR7_HELRO
Uncharacterized protein
Search

0.64	GO:0010952	positive regulation of peptidase activity
0.63	GO:0030198	extracellular matrix organization
0.45	GO:0072378	blood coagulation, fibrin clot formation
0.45	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading
0.45	GO:2000647	negative regulation of stem cell proliferation
0.44	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.43	GO:2000146	negative regulation of cell motility
0.38	GO:0007566	embryo implantation
0.38	GO:1904188	negative regulation of transformation of host cell by virus
0.37	GO:1904237	positive regulation of substrate-dependent cell migration, cell attachment to substrate

0.70	GO:0005509	calcium ion binding
0.65	GO:0016504	peptidase activator activity
0.50	GO:0005201	extracellular matrix structural constituent
0.46	GO:0070051	fibrinogen binding
0.45	GO:0001968	fibronectin binding
0.43	GO:0008022	protein C-terminus binding
0.41	GO:0042802	identical protein binding
0.38	GO:0005178	integrin binding
0.34	GO:0004725	protein tyrosine phosphatase activity
0.34	GO:0005044	scavenger receptor activity

0.59	GO:0005578	proteinaceous extracellular matrix
0.46	GO:0071953	elastic fiber
0.45	GO:0005577	fibrinogen complex
0.36	GO:0070062	extracellular exosome
0.32	GO:0005622	intracellular
0.30	GO:0016020	membrane

0.34

GO:0004725

tr|T1FQR8|T1FQR8_HELRO
Uncharacterized protein
Search

0.51	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.49	GO:0000733	DNA strand renaturation
0.48	GO:0031297	replication fork processing
0.43	GO:0036292	DNA rewinding
0.42	GO:0006281	DNA repair
0.39	GO:0030491	heteroduplex formation
0.38	GO:0048478	replication fork protection
0.38	GO:0009411	response to UV
0.38	GO:0006338	chromatin remodeling
0.38	GO:0045910	negative regulation of DNA recombination

0.55	GO:0004386	helicase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0004519	endonuclease activity
0.50	GO:0036310	annealing helicase activity
0.45	GO:0046872	metal ion binding
0.39	GO:0070530	K63-linked polyubiquitin modification-dependent protein binding
0.36	GO:0004536	deoxyribonuclease activity
0.36	GO:0008094	DNA-dependent ATPase activity

0.39	GO:0044427	chromosomal part
0.38	GO:0005700	polytene chromosome
0.38	GO:0005634	nucleus
0.37	GO:0031974	membrane-enclosed lumen
0.34	GO:1904949	ATPase complex
0.33	GO:0009941	chloroplast envelope
0.33	GO:0000938	GARP complex
0.32	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0004674

tr|T1FQR9|T1FQR9_HELRO
Uncharacterized protein
Search

0.49	GO:2000031	regulation of salicylic acid mediated signaling pathway
0.49	GO:0071446	cellular response to salicylic acid stimulus
0.44	GO:0031347	regulation of defense response
0.42	GO:0006468	protein phosphorylation
0.36	GO:0005975	carbohydrate metabolic process
0.36	GO:0006508	proteolysis

0.42	GO:0004672	protein kinase activity
0.42	GO:0030507	spectrin binding
0.39	GO:0032559	adenyl ribonucleotide binding
0.39	GO:0008144	drug binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.37	GO:0008236	serine-type peptidase activity

0.48	GO:1905369	endopeptidase complex
0.42	GO:0043234	protein complex
0.37	GO:0044424	intracellular part
0.30	GO:0016020	membrane

0.38

GO:0004553

tr|T1FQS0|T1FQS0_HELRO
Pyruvate dehydrogenase E1 component subunit alpha
Search

0.52	Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

0.78	GO:0006086	acetyl-CoA biosynthetic process from pyruvate
0.53	GO:0055114	oxidation-reduction process
0.34	GO:0006006	glucose metabolic process
0.34	GO:0006101	citrate metabolic process
0.34	GO:0019362	pyridine nucleotide metabolic process
0.34	GO:0006091	generation of precursor metabolites and energy
0.33	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:0046031	ADP metabolic process
0.33	GO:0006165	nucleoside diphosphate phosphorylation
0.33	GO:0016052	carbohydrate catabolic process

0.77	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity
0.35	GO:0034604	pyruvate dehydrogenase (NAD+) activity
0.34	GO:2001070	starch binding
0.34	GO:0008528	G-protein coupled peptide receptor activity
0.33	GO:0008081	phosphoric diester hydrolase activity

0.54	GO:0043231	intracellular membrane-bounded organelle
0.37	GO:0045254	pyruvate dehydrogenase complex
0.35	GO:0043233	organelle lumen
0.34	GO:0044446	intracellular organelle part
0.32	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

0.77	EC:1.2.4.1	GO:0004739
0.35	KEGG:R00209	GO:0034604

tr|T1FQS1|T1FQS1_HELRO
Integrin beta
Search

0.38	Integrin beta

0.79	GO:0007229	integrin-mediated signaling pathway
0.69	GO:0007155	cell adhesion
0.36	GO:0031581	hemidesmosome assembly
0.34	GO:0048870	cell motility
0.32	GO:0007186	G-protein coupled receptor signaling pathway

0.47	GO:0004872	receptor activity
0.34	GO:0003723	RNA binding
0.33	GO:0005509	calcium ion binding
0.32	GO:0004871	signal transducer activity

0.55	GO:0008305	integrin complex
0.39	GO:0071438	invadopodium membrane
0.38	GO:0032587	ruffle membrane
0.38	GO:0097610	cell surface furrow
0.38	GO:0042470	melanosome
0.38	GO:0030027	lamellipodium
0.38	GO:0032155	cell division site part
0.37	GO:0030054	cell junction

tr|T1FQS2|T1FQS2_HELRO
Integrin beta
Search

0.38	Integrin beta

0.80	GO:0007229	integrin-mediated signaling pathway
0.74	GO:0007160	cell-matrix adhesion
0.53	GO:0034113	heterotypic cell-cell adhesion
0.52	GO:0007159	leukocyte cell-cell adhesion
0.52	GO:0043113	receptor clustering
0.52	GO:0072678	T cell migration
0.51	GO:0045123	cellular extravasation
0.50	GO:0034446	substrate adhesion-dependent cell spreading
0.49	GO:0001667	ameboidal-type cell migration
0.39	GO:0043315	positive regulation of neutrophil degranulation

0.59	GO:0004872	receptor activity
0.49	GO:0050839	cell adhesion molecule binding
0.37	GO:0019901	protein kinase binding
0.37	GO:0031072	heat shock protein binding
0.35	GO:0004871	signal transducer activity
0.35	GO:0104005	hijacked molecular function
0.34	GO:0098531	transcription factor activity, direct ligand regulated sequence-specific DNA binding
0.33	GO:0003723	RNA binding
0.33	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.33	GO:0046872	metal ion binding

0.73	GO:0008305	integrin complex
0.47	GO:0009986	cell surface
0.37	GO:0044853	plasma membrane raft
0.37	GO:0070062	extracellular exosome
0.36	GO:0099568	cytoplasmic region
0.32	GO:0005634	nucleus

tr|T1FQS3|T1FQS3_HELRO
Uncharacterized protein
Search

0.49	GO:0045454	cell redox homeostasis
0.44	GO:0045332	phospholipid translocation
0.41	GO:0006364	rRNA processing
0.38	GO:0034471	ncRNA 5'-end processing
0.38	GO:0032259	methylation
0.38	GO:0006470	protein dephosphorylation
0.37	GO:0042274	ribosomal small subunit biogenesis
0.37	GO:0007018	microtubule-based movement
0.37	GO:0016567	protein ubiquitination
0.37	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic

0.44	GO:0003756	protein disulfide isomerase activity
0.44	GO:0004012	phospholipid-translocating ATPase activity
0.42	GO:0008270	zinc ion binding
0.39	GO:0000287	magnesium ion binding
0.39	GO:0032559	adenyl ribonucleotide binding
0.39	GO:0004722	protein serine/threonine phosphatase activity
0.39	GO:0008144	drug binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0008168	methyltransferase activity
0.38	GO:0003676	nucleic acid binding

0.41	GO:0032040	small-subunit processome
0.37	GO:0005730	nucleolus
0.30	GO:0016021	integral component of membrane

0.44

EC:5.3.4.1

GO:0003756

tr|T1FQS4|T1FQS4_HELRO
Uncharacterized protein
Search

0.57	GO:0015711	organic anion transport
0.54	GO:0055085	transmembrane transport
0.39	GO:0042144	vacuole fusion, non-autophagic
0.37	GO:0010038	response to metal ion
0.37	GO:0006749	glutathione metabolic process
0.37	GO:0015849	organic acid transport
0.36	GO:0042908	xenobiotic transport
0.36	GO:0045454	cell redox homeostasis
0.35	GO:0071705	nitrogen compound transport
0.35	GO:0015893	drug transport

0.65	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.59	GO:0008514	organic anion transmembrane transporter activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0005342	organic acid transmembrane transporter activity
0.36	GO:0042910	xenobiotic transmembrane transporter activity
0.36	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.35	GO:0015318	inorganic molecular entity transmembrane transporter activity

0.56	GO:0005887	integral component of plasma membrane
0.38	GO:0000329	fungal-type vacuole membrane
0.35	GO:0016323	basolateral plasma membrane

0.36

EC:1.3.1.74

GO:0032440

tr|T1FQS5|T1FQS5_HELRO
Uncharacterized protein
Search

0.55	GO:0055085	transmembrane transport
0.46	GO:0015711	organic anion transport
0.45	GO:0099039	sphingolipid translocation
0.44	GO:0042939	tripeptide transport
0.44	GO:0042908	xenobiotic transport
0.43	GO:0072337	modified amino acid transport
0.42	GO:0042493	response to drug
0.42	GO:0072348	sulfur compound transport
0.42	GO:0051181	cofactor transport
0.41	GO:0015748	organophosphate ester transport

0.65	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0034634	glutathione transmembrane transporter activity
0.46	GO:0046623	sphingolipid-translocating ATPase activity
0.44	GO:0042910	xenobiotic transmembrane transporter activity
0.42	GO:0004012	phospholipid-translocating ATPase activity
0.42	GO:0015238	drug transmembrane transporter activity
0.34	GO:0090482	vitamin transmembrane transporter activity

0.49	GO:0016323	basolateral plasma membrane
0.47	GO:0005887	integral component of plasma membrane
0.36	GO:0031088	platelet dense granule membrane
0.35	GO:0016324	apical plasma membrane
0.34	GO:0070062	extracellular exosome
0.34	GO:0005929	cilium

0.42

EC:3.6.3.1

GO:0004012

tr|T1FQS6|T1FQS6_HELRO
Uncharacterized protein
Search

tr|T1FQS7|T1FQS7_HELRO
Uncharacterized protein
Search

0.80	GO:2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.60	GO:0007253	cytoplasmic sequestering of NF-kappaB
0.55	GO:0006893	Golgi to plasma membrane transport
0.55	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.54	GO:0006878	cellular copper ion homeostasis
0.42	GO:0006468	protein phosphorylation
0.38	GO:0046854	phosphatidylinositol phosphorylation

0.80	GO:0097602	cullin family protein binding
0.45	GO:0003924	GTPase activity
0.44	GO:0032550	purine ribonucleoside binding
0.44	GO:0019001	guanyl nucleotide binding
0.43	GO:0032555	purine ribonucleotide binding
0.43	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.42	GO:0016301	kinase activity
0.40	GO:0140096	catalytic activity, acting on a protein
0.40	GO:0030554	adenyl nucleotide binding

0.30

GO:0005623

cell

0.43

GO:0016773

tr|T1FQS8|T1FQS8_HELRO
Uncharacterized protein
Search

tr|T1FQS9|T1FQS9_HELRO
Uncharacterized protein
Search

tr|T1FQT0|T1FQT0_HELRO
Uncharacterized protein
Search

tr|T1FQT1|T1FQT1_HELRO
Uncharacterized protein
Search

SLC5A8

0.62	Solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6

0.55

GO:0055085

transmembrane transport

0.57

GO:0022857

transmembrane transporter activity

0.30

GO:0044425

membrane part

tr|T1FQT2|T1FQT2_HELRO
Uncharacterized protein
Search

UBXN7

0.85	UBX domain-containing protein 7

0.39

GO:0043687

post-translational protein modification

0.78	GO:0043130	ubiquitin binding
0.77	GO:0031625	ubiquitin protein ligase binding
0.70	GO:0008134	transcription factor binding
0.34	GO:0046872	metal ion binding

0.85	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex
0.75	GO:0016604	nuclear body
0.37	GO:0005829	cytosol

tr|T1FQT3|T1FQT3_HELRO
Uncharacterized protein
Search

tr|T1FQT4|T1FQT4_HELRO
Uncharacterized protein
Search

tr|T1FQT5|T1FQT5_HELRO
Uncharacterized protein
Search

0.41	GO:0006468	protein phosphorylation
0.38	GO:0007606	sensory perception of chemical stimulus
0.38	GO:0006413	translational initiation
0.38	GO:0006030	chitin metabolic process
0.37	GO:0007018	microtubule-based movement
0.36	GO:0043254	regulation of protein complex assembly
0.36	GO:2001141	regulation of RNA biosynthetic process
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression
0.35	GO:0005975	carbohydrate metabolic process

0.41	GO:0003723	RNA binding
0.40	GO:0004672	protein kinase activity
0.38	GO:0097367	carbohydrate derivative binding
0.38	GO:0017076	purine nucleotide binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0003777	microtubule motor activity
0.37	GO:0008017	microtubule binding
0.37	GO:0003924	GTPase activity
0.37	GO:0008144	drug binding
0.36	GO:0003700	DNA binding transcription factor activity

0.38	GO:0031588	nucleotide-activated protein kinase complex
0.38	GO:0005871	kinesin complex
0.36	GO:0005576	extracellular region
0.35	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.36

GO:0004553

tr|T1FQT6|T1FQT6_HELRO
Uncharacterized protein
Search

0.51	GO:0006887	exocytosis
0.38	GO:0030245	cellulose catabolic process
0.34	GO:0055085	transmembrane transport

0.39	GO:0030246	carbohydrate binding
0.38	GO:0008810	cellulase activity
0.35	GO:0003676	nucleic acid binding

0.54	GO:0071203	WASH complex
0.52	GO:0005764	lysosome
0.36	GO:0043190	ATP-binding cassette (ABC) transporter complex
0.36	GO:0005634	nucleus

0.38

EC:3.2.1.4

GO:0008810

tr|T1FQT7|T1FQT7_HELRO
Uncharacterized protein
Search

0.41	GO:0002682	regulation of immune system process
0.38	GO:0005975	carbohydrate metabolic process
0.35	GO:0006508	proteolysis

0.46	GO:0001681	sialate O-acetylesterase activity
0.36	GO:0008236	serine-type peptidase activity

0.30

GO:0031224

intrinsic component of membrane

0.46

EC:3.1.1.53

GO:0001681

tr|T1FQT8|T1FQT8_HELRO
Uncharacterized protein
Search

0.66	GO:0006364	rRNA processing
0.44	GO:0042274	ribosomal small subunit biogenesis
0.40	GO:0034471	ncRNA 5'-end processing
0.39	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.37	GO:0000027	ribosomal large subunit assembly
0.35	GO:0007283	spermatogenesis
0.35	GO:0051321	meiotic cell cycle
0.35	GO:0046907	intracellular transport
0.34	GO:0043087	regulation of GTPase activity
0.34	GO:0030154	cell differentiation

0.35	GO:0016887	ATPase activity
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0008144	drug binding
0.33	GO:0003968	RNA-directed 5'-3' RNA polymerase activity
0.33	GO:0005515	protein binding
0.33	GO:0034511	U3 snoRNA binding
0.33	GO:0030234	enzyme regulator activity
0.33	GO:0016301	kinase activity

0.76	GO:0032040	small-subunit processome
0.44	GO:0005730	nucleolus
0.39	GO:0019013	viral nucleocapsid
0.34	GO:0005829	cytosol
0.33	GO:0030686	90S preribosome
0.33	GO:0031965	nuclear membrane
0.33	GO:0000781	chromosome, telomeric region
0.32	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.35

GO:0016887

tr|T1FQT9|T1FQT9_HELRO
Uncharacterized protein
Search

0.42	GO:0006468	protein phosphorylation
0.41	GO:0034670	chemotaxis to arachidonic acid
0.41	GO:0097231	cell motility in response to calcium ion
0.41	GO:0007010	cytoskeleton organization
0.41	GO:0008039	synaptic target recognition
0.41	GO:1903506	regulation of nucleic acid-templated transcription
0.41	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.40	GO:0010468	regulation of gene expression
0.40	GO:0031152	aggregation involved in sorocarp development
0.40	GO:0032507	maintenance of protein location in cell

0.47	GO:0045735	nutrient reservoir activity
0.42	GO:0003676	nucleic acid binding
0.42	GO:0004672	protein kinase activity
0.40	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
0.39	GO:0030554	adenyl nucleotide binding
0.39	GO:0003700	DNA binding transcription factor activity
0.39	GO:0070679	inositol 1,4,5 trisphosphate binding
0.39	GO:0097367	carbohydrate derivative binding
0.39	GO:0008144	drug binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding

0.45	GO:0005634	nucleus
0.41	GO:0016010	dystrophin-associated glycoprotein complex
0.38	GO:0030659	cytoplasmic vesicle membrane
0.37	GO:0005829	cytosol
0.37	GO:0005783	endoplasmic reticulum
0.37	GO:0005667	transcription factor complex
0.30	GO:0016021	integral component of membrane

0.38

EC:3.1.3.33

GO:0004651

tr|T1FQU0|T1FQU0_HELRO
Uncharacterized protein
Search

0.77	GO:0035725	sodium ion transmembrane transport
0.48	GO:0055078	sodium ion homeostasis
0.47	GO:0050891	multicellular organismal water homeostasis
0.38	GO:0050909	sensory perception of taste
0.34	GO:0016567	protein ubiquitination
0.34	GO:0050896	response to stimulus
0.34	GO:0006487	protein N-linked glycosylation
0.34	GO:0008217	regulation of blood pressure
0.34	GO:0040011	locomotion

0.81	GO:0005272	sodium channel activity
0.59	GO:0099094	ligand-gated cation channel activity
0.46	GO:0050699	WW domain binding
0.35	GO:0061630	ubiquitin protein ligase activity
0.34	GO:0016779	nucleotidyltransferase activity
0.33	GO:0008270	zinc ion binding
0.33	GO:0003779	actin binding

0.46	GO:0060170	ciliary membrane
0.46	GO:0034706	sodium channel complex
0.46	GO:0016324	apical plasma membrane
0.45	GO:0031514	motile cilium
0.44	GO:0070062	extracellular exosome
0.41	GO:0005887	integral component of plasma membrane
0.36	GO:0005737	cytoplasm
0.35	GO:0009897	external side of plasma membrane
0.35	GO:0043025	neuronal cell body
0.34	GO:0044446	intracellular organelle part

0.34

GO:0016779

tr|T1FQU1|T1FQU1_HELRO
Uncharacterized protein
Search

tr|T1FQU2|T1FQU2_HELRO
Uncharacterized protein
Search

tr|T1FQU3|T1FQU3_HELRO
Uncharacterized protein
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tr|T1FQU4|T1FQU4_HELRO
Uncharacterized protein
Search

0.11	Aminopeptidase

0.61	GO:0006508	proteolysis
0.53	GO:0002002	regulation of angiotensin levels in blood
0.48	GO:0042445	hormone metabolic process
0.46	GO:0051604	protein maturation
0.45	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I
0.43	GO:0006518	peptide metabolic process
0.37	GO:1901565	organonitrogen compound catabolic process
0.36	GO:0044248	cellular catabolic process
0.34	GO:0031288	sorocarp morphogenesis
0.33	GO:0098609	cell-cell adhesion

0.68	GO:0004177	aminopeptidase activity
0.67	GO:0008237	metallopeptidase activity
0.63	GO:0008270	zinc ion binding
0.39	GO:0042277	peptide binding
0.33	GO:0019901	protein kinase binding

0.41	GO:0005783	endoplasmic reticulum
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0031984	organelle subcompartment
0.33	GO:0005815	microtubule organizing center
0.33	GO:0005874	microtubule
0.32	GO:0005654	nucleoplasm
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.68

EC:3.4.11

GO:0004177

tr|T1FQU5|T1FQU5_HELRO
Uncharacterized protein
Search

tr|T1FQU6|T1FQU6_HELRO
Uncharacterized protein
Search

tr|T1FQU7|T1FQU7_HELRO
Uncharacterized protein
Search

tr|T1FQU8|T1FQU8_HELRO
Uncharacterized protein
Search

LOC106156405

0.92	Cys-loop ligand-gated ion channel

0.61	GO:0007165	signal transduction
0.60	GO:0034220	ion transmembrane transport

0.76	GO:0005230	extracellular ligand-gated ion channel activity
0.70	GO:0099600	transmembrane receptor activity
0.65	GO:0038023	signaling receptor activity

0.30

GO:0031224

intrinsic component of membrane

tr|T1FQU9|T1FQU9_HELRO
Uncharacterized protein
Search

0.53	GO:0055114	oxidation-reduction process
0.35	GO:0043043	peptide biosynthetic process
0.34	GO:0044267	cellular protein metabolic process
0.34	GO:0010467	gene expression
0.34	GO:0009059	macromolecule biosynthetic process

0.36	GO:0003735	structural constituent of ribosome
0.30	GO:0003824	catalytic activity

0.35	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

tr|T1FQV0|T1FQV0_HELRO
Uncharacterized protein
Search

tr|T1FQV1|T1FQV1_HELRO
Uncharacterized protein
Search

0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.75	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.46	GO:0023014	signal transduction by protein phosphorylation
0.45	GO:0035556	intracellular signal transduction
0.39	GO:0008071	maternal determination of dorsal/ventral axis, ovarian follicular epithelium, soma encoded
0.39	GO:0035310	notum cell fate specification
0.39	GO:0046673	negative regulation of compound eye retinal cell programmed cell death
0.39	GO:0007395	dorsal closure, spreading of leading edge cells
0.39	GO:0016330	second mitotic wave involved in compound eye morphogenesis
0.39	GO:0007479	leg disc proximal/distal pattern formation

0.77	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.56	GO:0004716	signal transducer, downstream of receptor, with protein tyrosine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.35	GO:0005102	receptor binding
0.34	GO:0042802	identical protein binding

0.39	GO:0035230	cytoneme
0.37	GO:0005622	intracellular
0.35	GO:0019897	extrinsic component of plasma membrane
0.35	GO:0009898	cytoplasmic side of plasma membrane
0.30	GO:0016021	integral component of membrane

0.77

EC:2.7.10.1

GO:0004714

tr|T1FQV2|T1FQV2_HELRO
Uncharacterized protein
Search

0.34	GO:0008333	endosome to lysosome transport
0.34	GO:0030178	negative regulation of Wnt signaling pathway
0.34	GO:0016055	Wnt signaling pathway
0.32	GO:0018106	peptidyl-histidine phosphorylation
0.32	GO:0023014	signal transduction by protein phosphorylation
0.32	GO:0000160	phosphorelay signal transduction system

0.54	GO:0003677	DNA binding
0.32	GO:0000155	phosphorelay sensor kinase activity

0.61	GO:0005634	nucleus
0.45	GO:0000785	chromatin
0.43	GO:0070013	intracellular organelle lumen
0.43	GO:1904949	ATPase complex
0.30	GO:0016021	integral component of membrane

0.32

GO:0000155

tr|T1FQV3|T1FQV3_HELRO
Uncharacterized protein
Search

tr|T1FQV4|T1FQV4_HELRO
Uncharacterized protein
Search

TYW1

0.59	S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase

0.66	GO:0008033	tRNA processing
0.52	GO:0055114	oxidation-reduction process
0.34	GO:0043043	peptide biosynthetic process
0.33	GO:0044267	cellular protein metabolic process
0.33	GO:0009059	macromolecule biosynthetic process

0.69	GO:0010181	FMN binding
0.67	GO:0051539	4 iron, 4 sulfur cluster binding
0.45	GO:0102521	tRNA-4-demethylwyosine synthase activity
0.36	GO:0046872	metal ion binding
0.35	GO:0019843	rRNA binding
0.34	GO:0003735	structural constituent of ribosome

0.34	GO:0005840	ribosome
0.30	GO:0016020	membrane

tr|T1FQV5|T1FQV5_HELRO
Uncharacterized protein
Search

0.47	GO:0008285	negative regulation of cell proliferation
0.39	GO:0007062	sister chromatid cohesion
0.39	GO:0030261	chromosome condensation
0.37	GO:0006260	DNA replication
0.34	GO:0051988	regulation of attachment of spindle microtubules to kinetochore
0.33	GO:0051301	cell division

0.70	GO:0008092	cytoskeletal protein binding
0.35	GO:0030554	adenyl nucleotide binding
0.35	GO:0032555	purine ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0003677	DNA binding

0.68	GO:0005856	cytoskeleton
0.34	GO:0005615	extracellular space
0.34	GO:0005737	cytoplasm

tr|T1FQV6|T1FQV6_HELRO
Uncharacterized protein
Search

tr|T1FQV7|T1FQV7_HELRO
Uncharacterized protein
Search

0.66	GO:0018108	peptidyl-tyrosine phosphorylation
0.55	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.45	GO:0007172	signal complex assembly
0.38	GO:0007417	central nervous system development
0.37	GO:1903034	regulation of response to wounding
0.36	GO:1901244	positive regulation of transcription from RNA polymerase II promoter involved in defense response to fungus
0.36	GO:0032101	regulation of response to external stimulus
0.36	GO:0006869	lipid transport
0.36	GO:0002922	positive regulation of humoral immune response
0.35	GO:0002833	positive regulation of response to biotic stimulus

0.67	GO:0004713	protein tyrosine kinase activity
0.56	GO:0019199	transmembrane receptor protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0005319	lipid transporter activity
0.34	GO:0004127	cytidylate kinase activity
0.34	GO:0004017	adenylate kinase activity
0.34	GO:0046983	protein dimerization activity
0.33	GO:0004252	serine-type endopeptidase activity

0.43	GO:0005925	focal adhesion
0.40	GO:0005856	cytoskeleton
0.33	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.67

GO:0004713

tr|T1FQV8|T1FQV8_HELRO
Uncharacterized protein
Search

0.77	Glutamate ionotropic receptor AMPA type subunit 3

0.80	GO:0060079	excitatory postsynaptic potential
0.77	GO:0035235	ionotropic glutamate receptor signaling pathway
0.60	GO:0034220	ion transmembrane transport
0.42	GO:0099566	regulation of postsynaptic cytosolic calcium ion concentration
0.41	GO:0060292	long term synaptic depression
0.41	GO:0031623	receptor internalization
0.41	GO:0007616	long-term memory

0.82	GO:0005234	extracellularly glutamate-gated ion channel activity
0.77	GO:0004970	ionotropic glutamate receptor activity
0.51	GO:0099094	ligand-gated cation channel activity
0.42	GO:0099583	neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration
0.40	GO:1904315	transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential

0.79	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.54	GO:0032281	AMPA glutamate receptor complex
0.42	GO:0032591	dendritic spine membrane
0.42	GO:0044308	axonal spine
0.40	GO:0014069	postsynaptic density
0.40	GO:0055037	recycling endosome
0.40	GO:0008021	synaptic vesicle
0.40	GO:0043025	neuronal cell body
0.39	GO:0009986	cell surface

tr|T1FQV9|T1FQV9_HELRO
Uncharacterized protein
Search

tr|T1FQW0|T1FQW0_HELRO
Uncharacterized protein
Search

HIF1AN

0.96	Hypoxia inducible factor 1 alpha subunit inhibitor

0.85	GO:0042265	peptidyl-asparagine hydroxylation
0.85	GO:0036138	peptidyl-histidine hydroxylation
0.85	GO:0042264	peptidyl-aspartic acid hydroxylation
0.83	GO:0061428	negative regulation of transcription from RNA polymerase II promoter in response to hypoxia
0.78	GO:0045663	positive regulation of myoblast differentiation
0.77	GO:0045746	negative regulation of Notch signaling pathway
0.60	GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway
0.58	GO:1901343	negative regulation of vasculature development
0.50	GO:0055114	oxidation-reduction process
0.40	GO:2001214	positive regulation of vasculogenesis

0.85	GO:0036139	peptidyl-histidine dioxygenase activity
0.85	GO:0036140	peptidyl-asparagine 3-dioxygenase activity
0.83	GO:0071532	ankyrin repeat binding
0.79	GO:0051059	NF-kappaB binding
0.78	GO:0005112	Notch binding
0.68	GO:0042803	protein homodimerization activity
0.65	GO:0031406	carboxylic acid binding
0.58	GO:0008270	zinc ion binding
0.57	GO:0005506	iron ion binding
0.51	GO:0048037	cofactor binding

0.72	GO:0048471	perinuclear region of cytoplasm
0.63	GO:0005654	nucleoplasm
0.62	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.44

EC:1.14.11.16

GO:0004597

tr|T1FQW1|T1FQW1_HELRO
Uncharacterized protein
Search

ATXN3

0.87	Ataxin 3 variant ref

0.76	GO:0016579	protein deubiquitination
0.46	GO:0035640	exploration behavior
0.45	GO:0071218	cellular response to misfolded protein
0.45	GO:0010810	regulation of cell-substrate adhesion
0.44	GO:0034605	cellular response to heat
0.43	GO:0006515	protein quality control for misfolded or incompletely synthesized proteins
0.43	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.41	GO:1904327	protein localization to cytosolic proteasome complex
0.39	GO:1904294	positive regulation of ERAD pathway
0.39	GO:0045104	intermediate filament cytoskeleton organization

0.80	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.44	GO:0031625	ubiquitin protein ligase binding
0.40	GO:0051117	ATPase binding
0.39	GO:0061578	Lys63-specific deubiquitinase activity
0.39	GO:1990380	Lys48-specific deubiquitinase activity
0.37	GO:0042802	identical protein binding
0.36	GO:0004407	histone deacetylase activity
0.36	GO:0001012	RNA polymerase II regulatory region DNA binding
0.34	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity
0.33	GO:0030976	thiamine pyrophosphate binding

0.46	GO:0042405	nuclear inclusion body
0.42	GO:0005759	mitochondrial matrix
0.39	GO:0005730	nucleolus
0.39	GO:0031966	mitochondrial membrane
0.37	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0005829	cytosol
0.36	GO:0005886	plasma membrane
0.34	GO:0016363	nuclear matrix
0.33	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.36

EC:3.5.1.98

GO:0004407

tr|T1FQW2|T1FQW2_HELRO
Uncharacterized protein
Search

ADCK1

0.93	AarF domain-containing protein kinase 1

0.59	GO:0006468	protein phosphorylation
0.35	GO:0055088	lipid homeostasis
0.34	GO:0007005	mitochondrion organization
0.33	GO:0006955	immune response
0.32	GO:0006508	proteolysis

0.59	GO:0004672	protein kinase activity
0.52	GO:0032559	adenyl ribonucleotide binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005164	tumor necrosis factor receptor binding
0.33	GO:0004222	metalloendopeptidase activity
0.32	GO:0008270	zinc ion binding

0.39	GO:0005739	mitochondrion
0.36	GO:0005576	extracellular region
0.33	GO:0019866	organelle inner membrane
0.33	GO:0031301	integral component of organelle membrane

0.33

GO:0004222

tr|T1FQW3|T1FQW3_HELRO
Uncharacterized protein
Search

tr|T1FQW4|T1FQW4_HELRO
Uncharacterized protein
Search

tr|T1FQW5|T1FQW5_HELRO
Uncharacterized protein
Search

tr|T1FQW6|T1FQW6_HELRO
Uncharacterized protein
Search

0.42	GO:0016360	sensory organ precursor cell fate determination
0.42	GO:0048190	wing disc dorsal/ventral pattern formation
0.39	GO:0031532	actin cytoskeleton reorganization
0.39	GO:0016567	protein ubiquitination
0.38	GO:0006357	regulation of transcription by RNA polymerase II
0.38	GO:0031285	regulation of sorocarp stalk cell differentiation
0.38	GO:1901261	regulation of sorocarp spore cell differentiation
0.37	GO:0070143	mitochondrial alanyl-tRNA aminoacylation
0.36	GO:0000915	actomyosin contractile ring assembly
0.36	GO:0038007	netrin-activated signaling pathway

0.39	GO:0004842	ubiquitin-protein transferase activity
0.38	GO:0030554	adenyl nucleotide binding
0.38	GO:0097367	carbohydrate derivative binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0008144	drug binding
0.37	GO:0005515	protein binding
0.37	GO:0003676	nucleic acid binding
0.37	GO:0003700	DNA binding transcription factor activity
0.36	GO:0046872	metal ion binding
0.36	GO:0005042	netrin receptor activity

0.41	GO:0045179	apical cortex
0.40	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0005813	centrosome
0.36	GO:0043231	intracellular membrane-bounded organelle
0.35	GO:0005875	microtubule associated complex
0.30	GO:0016020	membrane

0.36	EC:6.1.1.7	GO:0004813
0.39	KEGG:R03876	GO:0004842

tr|T1FQW7|T1FQW7_HELRO
Uncharacterized protein
Search

0.38	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.38	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.37	GO:0006396	RNA processing
0.36	GO:0015031	protein transport
0.35	GO:0043412	macromolecule modification
0.35	GO:1903506	regulation of nucleic acid-templated transcription
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0006325	chromatin organization
0.35	GO:0010468	regulation of gene expression
0.34	GO:0016310	phosphorylation

0.39	GO:0032296	double-stranded RNA-specific ribonuclease activity
0.38	GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters
0.35	GO:0004672	protein kinase activity
0.34	GO:0003700	DNA binding transcription factor activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008270	zinc ion binding
0.34	GO:0022857	transmembrane transporter activity
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.38	GO:0030126	COPI vesicle coat
0.35	GO:0000139	Golgi membrane
0.35	GO:0005634	nucleus
0.34	GO:0031966	mitochondrial membrane
0.34	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

0.38

EC:3.1.26

GO:0016891

tr|T1FQW8|T1FQW8_HELRO
Non-specific serine/threonine protein kinase
Search

CHEK1

0.90	Serine/threonine-protein kinase grp

0.76	GO:0000077	DNA damage checkpoint
0.63	GO:0006468	protein phosphorylation
0.54	GO:0010767	regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage
0.53	GO:0048096	chromatin-mediated maintenance of transcription
0.52	GO:0045930	negative regulation of mitotic cell cycle
0.52	GO:2000615	regulation of histone H3-K9 acetylation
0.51	GO:1902742	apoptotic process involved in development
0.51	GO:0018210	peptidyl-threonine modification
0.50	GO:0000086	G2/M transition of mitotic cell cycle
0.49	GO:0001833	inner cell mass cell proliferation

0.69	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0035173	histone kinase activity
0.37	GO:0019904	protein domain specific binding
0.34	GO:0004576	oligosaccharyl transferase activity
0.33	GO:0050660	flavin adenine dinucleotide binding
0.33	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors

0.46	GO:0000785	chromatin
0.46	GO:0005657	replication fork
0.45	GO:0005654	nucleoplasm
0.39	GO:0000794	condensed nuclear chromosome
0.39	GO:0005813	centrosome
0.37	GO:0000781	chromosome, telomeric region
0.37	GO:0005737	cytoplasm
0.35	GO:0005615	extracellular space
0.34	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.69

GO:0004674

tr|T1FQW9|T1FQW9_HELRO
Uncharacterized protein
Search

0.54	GO:0043044	ATP-dependent chromatin remodeling
0.50	GO:0016569	covalent chromatin modification
0.42	GO:0006468	protein phosphorylation
0.41	GO:0006508	proteolysis
0.40	GO:0098734	macromolecule depalmitoylation
0.39	GO:0006355	regulation of transcription, DNA-templated
0.38	GO:0046854	phosphatidylinositol phosphorylation
0.38	GO:0007018	microtubule-based movement
0.38	GO:0043632	modification-dependent macromolecule catabolic process
0.38	GO:0044257	cellular protein catabolic process

0.48	GO:0004386	helicase activity
0.46	GO:0032559	adenyl ribonucleotide binding
0.45	GO:0008144	drug binding
0.45	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0004674	protein serine/threonine kinase activity
0.44	GO:0016887	ATPase activity
0.43	GO:0003677	DNA binding
0.43	GO:0008234	cysteine-type peptidase activity
0.41	GO:0000285	1-phosphatidylinositol-3-phosphate 5-kinase activity
0.40	GO:0004530	deoxyribonuclease I activity

0.55	GO:0016589	NURF complex
0.30	GO:0016020	membrane

0.44	EC:2.7.11	GO:0004674
0.41	KEGG:R05802	GO:0000285

tr|T1FQX0|T1FQX0_HELRO
Uncharacterized protein
Search

0.41	GO:0007155	cell adhesion
0.39	GO:0006030	chitin metabolic process
0.38	GO:0007275	multicellular organism development
0.37	GO:2000026	regulation of multicellular organismal development
0.37	GO:0090287	regulation of cellular response to growth factor stimulus
0.37	GO:0009653	anatomical structure morphogenesis
0.36	GO:0071694	maintenance of protein location in extracellular region
0.36	GO:0035581	sequestering of extracellular ligand from receptor
0.36	GO:0010721	negative regulation of cell development
0.35	GO:0006357	regulation of transcription by RNA polymerase II

0.67	GO:0005509	calcium ion binding
0.47	GO:0005201	extracellular matrix structural constituent
0.40	GO:0005540	hyaluronic acid binding
0.38	GO:0008061	chitin binding
0.36	GO:0005178	integrin binding
0.36	GO:0008201	heparin binding
0.35	GO:0042802	identical protein binding
0.34	GO:0050436	microfibril binding
0.34	GO:0050431	transforming growth factor beta binding
0.33	GO:0004252	serine-type endopeptidase activity

0.47	GO:0031012	extracellular matrix
0.37	GO:0005615	extracellular space
0.35	GO:0099512	supramolecular fiber
0.32	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.33

GO:0004252

tr|T1FQX1|T1FQX1_HELRO
Acyl-coenzyme A oxidase
Search

0.56	Peroxisomal acyl-coenzyme A oxidase

0.75	GO:0006635	fatty acid beta-oxidation
0.49	GO:1902884	positive regulation of response to oxidative stress
0.46	GO:0010942	positive regulation of cell death
0.35	GO:0006699	bile acid biosynthetic process

0.81	GO:0003997	acyl-CoA oxidase activity
0.70	GO:0071949	FAD binding
0.52	GO:0033791	3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity
0.44	GO:0005102	receptor binding
0.42	GO:0003995	acyl-CoA dehydrogenase activity
0.35	GO:0042803	protein homodimerization activity

0.74	GO:0005777	peroxisome
0.43	GO:0005829	cytosol
0.35	GO:0031907	microbody lumen

0.81

EC:1.3.3.6

GO:0003997

tr|T1FQX2|T1FQX2_HELRO
Uncharacterized protein
Search

0.49	GO:0036211	protein modification process
0.47	GO:0044267	cellular protein metabolic process
0.45	GO:0016569	covalent chromatin modification
0.44	GO:0006366	transcription by RNA polymerase II
0.41	GO:0016310	phosphorylation
0.41	GO:0000349	generation of catalytic spliceosome for first transesterification step
0.39	GO:1903341	regulation of meiotic DNA double-strand break formation
0.38	GO:0043326	chemotaxis to folate
0.38	GO:0060176	regulation of aggregation involved in sorocarp development
0.38	GO:0043327	chemotaxis to cAMP

0.49	GO:0043531	ADP binding
0.46	GO:0004842	ubiquitin-protein transferase activity
0.45	GO:0032947	protein complex scaffold activity
0.45	GO:0043130	ubiquitin binding
0.44	GO:0003682	chromatin binding
0.43	GO:0042802	identical protein binding
0.43	GO:0004672	protein kinase activity
0.39	GO:0043565	sequence-specific DNA binding
0.39	GO:0003743	translation initiation factor activity
0.38	GO:0042800	histone methyltransferase activity (H3-K4 specific)

0.46	GO:0046695	SLIK (SAGA-like) complex
0.45	GO:0000124	SAGA complex
0.45	GO:0005669	transcription factor TFIID complex
0.41	GO:0071006	U2-type catalytic step 1 spliceosome
0.40	GO:0000974	Prp19 complex
0.37	GO:0048188	Set1C/COMPASS complex
0.37	GO:0000781	chromosome, telomeric region
0.37	GO:0005881	cytoplasmic microtubule
0.36	GO:0005815	microtubule organizing center
0.30	GO:0016020	membrane

0.46

GO:0004842

tr|T1FQX3|T1FQX3_HELRO
Uncharacterized protein
Search

tr|T1FQX4|T1FQX4_HELRO
Uncharacterized protein
Search

0.30

GO:0044425

membrane part

tr|T1FQX5|T1FQX5_HELRO
Uncharacterized protein
Search

tr|T1FQX6|T1FQX6_HELRO
Uncharacterized protein
Search

tr|T1FQX7|T1FQX7_HELRO
Uncharacterized protein
Search

0.66	GO:0008033	tRNA processing
0.56	GO:0043628	ncRNA 3'-end processing
0.52	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.49	GO:0000959	mitochondrial RNA metabolic process
0.44	GO:0140053	mitochondrial gene expression
0.37	GO:0006355	regulation of transcription, DNA-templated
0.36	GO:0055114	oxidation-reduction process

0.53	GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters
0.38	GO:0003700	DNA binding transcription factor activity
0.36	GO:0016491	oxidoreductase activity

0.41	GO:0005739	mitochondrion
0.40	GO:0005634	nucleus
0.37	GO:0009295	nucleoid
0.36	GO:0031974	membrane-enclosed lumen
0.35	GO:0043232	intracellular non-membrane-bounded organelle
0.35	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.53

EC:3.1.26

GO:0016891

tr|T1FQX8|T1FQX8_HELRO
Uncharacterized protein
Search

0.80

GO:0001009

transcription by RNA polymerase III

0.87	GO:0001003	RNA polymerase III type 2 promoter sequence-specific DNA binding
0.86	GO:0001002	RNA polymerase III type 1 promoter sequence-specific DNA binding

0.86

GO:0000127

transcription factor TFIIIC complex

tr|T1FQX9|T1FQX9_HELRO
Uncharacterized protein
Search

tr|T1FQY0|T1FQY0_HELRO
Uncharacterized protein
Search

TM6SF1

0.76	LOW QUALITY PROTEIN: transmembrane 6 superfamily member 1

0.35

GO:0007155

cell adhesion

0.36

GO:0005540

hyaluronic acid binding

0.42	GO:0005765	lysosomal membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1FQY1|T1FQY1_HELRO
Uncharacterized protein
Search

0.39	GO:0006368	transcription elongation from RNA polymerase II promoter
0.38	GO:0016570	histone modification
0.38	GO:0035317	imaginal disc-derived wing hair organization
0.37	GO:0017157	regulation of exocytosis
0.35	GO:0016192	vesicle-mediated transport
0.34	GO:0006508	proteolysis
0.34	GO:2001141	regulation of RNA biosynthetic process
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression

0.38	GO:0008923	lysine decarboxylase activity
0.37	GO:0005515	protein binding
0.36	GO:0008234	cysteine-type peptidase activity
0.35	GO:0003676	nucleic acid binding
0.35	GO:0016874	ligase activity
0.35	GO:0008270	zinc ion binding
0.34	GO:0003700	DNA binding transcription factor activity
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0008144	drug binding

0.39	GO:0016593	Cdc73/Paf1 complex
0.30	GO:0016020	membrane

0.38	EC:4.1.1.18	GO:0008923
0.38	KEGG:R00462	GO:0008923

tr|T1FQY2|T1FQY2_HELRO
Uncharacterized protein
Search

CWC27

0.82	Peptidyl-prolyl cis-trans isomerase SDCCAG10

0.72	GO:0000413	protein peptidyl-prolyl isomerization
0.68	GO:0006457	protein folding
0.35	GO:0016485	protein processing
0.34	GO:0043085	positive regulation of catalytic activity
0.34	GO:0006506	GPI anchor biosynthetic process
0.34	GO:0000398	mRNA splicing, via spliceosome
0.33	GO:0006757	ATP generation from ADP
0.33	GO:0006090	pyruvate metabolic process
0.33	GO:0030001	metal ion transport
0.33	GO:0016052	carbohydrate catabolic process

0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.35	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity
0.34	GO:0004807	triose-phosphate isomerase activity
0.33	GO:0046873	metal ion transmembrane transporter activity

0.51	GO:0071013	catalytic step 2 spliceosome
0.46	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.72	EC:5.2.1.8	GO:0003755
0.34	KEGG:R01015	GO:0004807

tr|T1FQY3|T1FQY3_HELRO
5-aminolevulinate synthase
Search

0.66	5-aminolevulinate synthase

0.72	GO:0006782	protoporphyrinogen IX biosynthetic process
0.41	GO:0040003	chitin-based cuticle development
0.33	GO:0043043	peptide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0010467	gene expression
0.32	GO:0055114	oxidation-reduction process
0.32	GO:0009059	macromolecule biosynthetic process

0.84	GO:0003870	5-aminolevulinate synthase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.36	GO:0016874	ligase activity
0.34	GO:0008113	peptide-methionine (S)-S-oxide reductase activity
0.34	GO:0042802	identical protein binding
0.33	GO:0008483	transaminase activity
0.33	GO:0003735	structural constituent of ribosome
0.32	GO:0003676	nucleic acid binding

0.73	GO:0005759	mitochondrial matrix
0.33	GO:0005654	nucleoplasm
0.33	GO:0005829	cytosol
0.33	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

0.84	EC:2.3.1.37	GO:0003870
0.84	KEGG:R00830	GO:0003870

tr|T1FQY4|T1FQY4_HELRO
Uncharacterized protein
Search

0.63

GO:0035556

intracellular signal transduction

0.45

GO:0005622

intracellular

tr|T1FQY5|T1FQY5_HELRO
Uncharacterized protein
Search

tr|T1FQY6|T1FQY6_HELRO
Uncharacterized protein
Search

0.10

Filamin-A

0.62	GO:0030029	actin filament-based process
0.62	GO:0030154	cell differentiation
0.60	GO:0007010	cytoskeleton organization
0.47	GO:0061061	muscle structure development
0.44	GO:0071346	cellular response to interferon-gamma
0.43	GO:0043588	skin development
0.43	GO:0008544	epidermis development
0.43	GO:0014706	striated muscle tissue development
0.42	GO:0060429	epithelium development
0.42	GO:0032989	cellular component morphogenesis

0.73	GO:0003779	actin binding
0.58	GO:0032403	protein complex binding
0.45	GO:0045296	cadherin binding
0.43	GO:0042802	identical protein binding
0.42	GO:0030506	ankyrin binding
0.35	GO:0017160	Ral GTPase binding
0.35	GO:0034987	immunoglobulin receptor binding
0.35	GO:0015459	potassium channel regulator activity
0.35	GO:0048365	Rac GTPase binding
0.35	GO:0044325	ion channel binding

0.44	GO:0097517	contractile actin filament bundle
0.44	GO:0042641	actomyosin
0.44	GO:0005829	cytosol
0.43	GO:0005903	brush border
0.43	GO:0045335	phagocytic vesicle
0.43	GO:0005925	focal adhesion
0.41	GO:0042383	sarcolemma
0.36	GO:0099512	supramolecular fiber
0.36	GO:0031523	Myb complex
0.34	GO:0005911	cell-cell junction

tr|T1FQY7|T1FQY7_HELRO
Uncharacterized protein
Search

tr|T1FQY8|T1FQY8_HELRO
Uncharacterized protein
Search

tr|T1FQY9|T1FQY9_HELRO
Uncharacterized protein
Search

tr|T1FQZ0|T1FQZ0_HELRO
Uncharacterized protein
Search

0.48	Serine/threonine-protein kinase Nek9

0.63

GO:0006468

protein phosphorylation

0.64	GO:0004672	protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

tr|T1FQZ1|T1FQZ1_HELRO
Uncharacterized protein
Search

0.20	ATP-dependent DNA helicase

0.65	GO:0006310	DNA recombination
0.62	GO:0032392	DNA geometric change
0.59	GO:0006260	DNA replication
0.58	GO:0006281	DNA repair
0.45	GO:0009432	SOS response
0.35	GO:0006265	DNA topological change
0.35	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.33	GO:0043043	peptide biosynthetic process
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.70	GO:0070035	purine NTP-dependent helicase activity
0.70	GO:0043138	3'-5' DNA helicase activity
0.64	GO:0042623	ATPase activity, coupled
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0003676	nucleic acid binding
0.36	GO:0008408	3'-5' exonuclease activity
0.35	GO:0003917	DNA topoisomerase type I activity
0.33	GO:0003735	structural constituent of ribosome

0.53	GO:0005634	nucleus
0.33	GO:0005840	ribosome

0.35

EC:5.99.1.2

GO:0003917

tr|T1FQZ2|T1FQZ2_HELRO
Uncharacterized protein
Search

tr|T1FQZ3|T1FQZ3_HELRO
Uncharacterized protein
Search

0.58	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.41	GO:0035458	cellular response to interferon-beta
0.39	GO:0000077	DNA damage checkpoint
0.36	GO:0006259	DNA metabolic process

0.62	GO:0004527	exonuclease activity
0.58	GO:0032407	MutSalpha complex binding
0.58	GO:0032405	MutLalpha complex binding
0.51	GO:0003676	nucleic acid binding
0.42	GO:0032558	adenyl deoxyribonucleotide binding
0.38	GO:0042803	protein homodimerization activity
0.38	GO:0004536	deoxyribonuclease activity
0.30	GO:0043167	ion binding

0.47	GO:0005829	cytosol
0.30	GO:0016020	membrane

tr|T1FQZ4|T1FQZ4_HELRO
Uncharacterized protein
Search

0.61	GO:0006508	proteolysis
0.50	GO:0006954	inflammatory response
0.46	GO:0060022	hard palate development
0.39	GO:0035202	tracheal pit formation in open tracheal system
0.39	GO:0007505	adult fat body development
0.39	GO:1901202	negative regulation of extracellular matrix assembly
0.39	GO:0003144	embryonic heart tube formation
0.39	GO:0003319	cardioblast migration to the midline involved in heart rudiment formation
0.39	GO:0007561	imaginal disc eversion
0.39	GO:0097156	fasciculation of motor neuron axon

0.70	GO:0004222	metalloendopeptidase activity
0.63	GO:0008270	zinc ion binding
0.34	GO:0003975	UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity
0.34	GO:0004435	phosphatidylinositol phospholipase C activity
0.34	GO:0008963	phospho-N-acetylmuramoyl-pentapeptide-transferase activity
0.34	GO:0016504	peptidase activator activity
0.32	GO:0005509	calcium ion binding
0.32	GO:0003676	nucleic acid binding

0.74	GO:0031012	extracellular matrix
0.38	GO:0005886	plasma membrane
0.37	GO:0030425	dendrite
0.37	GO:0009986	cell surface
0.36	GO:0098552	side of membrane
0.36	GO:0031225	anchored component of membrane
0.34	GO:0035579	specific granule membrane
0.33	GO:0005581	collagen trimer
0.30	GO:0016021	integral component of membrane

0.70	EC:3.4.24	GO:0004222
0.34	KEGG:R03435	GO:0004435

tr|T1FQZ5|T1FQZ5_HELRO
Uncharacterized protein
Search

0.30

GO:0044425

membrane part

tr|T1FQZ6|T1FQZ6_HELRO
Uncharacterized protein
Search

tr|T1FQZ7|T1FQZ7_HELRO
Uncharacterized protein
Search

tr|T1FQZ8|T1FQZ8_HELRO
Uncharacterized protein
Search

tr|T1FQZ9|T1FQZ9_HELRO
Uncharacterized protein
Search

tr|T1FR00|T1FR00_HELRO
Uncharacterized protein
Search

tr|T1FR01|T1FR01_HELRO
Uncharacterized protein
Search

tr|T1FR02|T1FR02_HELRO
Uncharacterized protein
Search

tr|T1FR03|T1FR03_HELRO
Uncharacterized protein
Search

0.36

GO:0006468

protein phosphorylation

0.36	GO:0004672	protein kinase activity
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0097367	carbohydrate derivative binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0031224

intrinsic component of membrane

tr|T1FR04|T1FR04_HELRO
Uncharacterized protein
Search

0.35	GO:0000398	mRNA splicing, via spliceosome
0.32	GO:0032774	RNA biosynthetic process

0.52	GO:0046872	metal ion binding
0.33	GO:0003723	RNA binding
0.33	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.33	GO:0005515	protein binding

0.48	GO:0016607	nuclear speck
0.36	GO:0071011	precatalytic spliceosome
0.36	GO:0071013	catalytic step 2 spliceosome
0.34	GO:0043234	protein complex

0.33

EC:2.7.7.6

GO:0003899

tr|T1FR05|T1FR05_HELRO
Uncharacterized protein
Search

tr|T1FR06|T1FR06_HELRO
Uncharacterized protein
Search

0.44

GO:0051726

regulation of cell cycle

0.57	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

tr|T1FR07|T1FR07_HELRO
Uncharacterized protein
Search

tr|T1FR08|T1FR08_HELRO
Uncharacterized protein
Search

0.74	Upstream stimulatory factor

0.43	GO:0000432	positive regulation of transcription from RNA polymerase II promoter by glucose
0.41	GO:0007595	lactation
0.41	GO:0055088	lipid homeostasis
0.37	GO:0006366	transcription by RNA polymerase II
0.36	GO:0019086	late viral transcription
0.35	GO:0032869	cellular response to insulin stimulus
0.35	GO:0001666	response to hypoxia
0.35	GO:0009411	response to UV
0.34	GO:0008203	cholesterol metabolic process
0.33	GO:0016042	lipid catabolic process

0.68	GO:0046983	protein dimerization activity
0.39	GO:0043425	bHLH transcription factor binding
0.39	GO:0070888	E-box binding
0.39	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.37	GO:0042802	identical protein binding
0.35	GO:0042826	histone deacetylase binding
0.35	GO:0019901	protein kinase binding
0.34	GO:0016298	lipase activity

0.37	GO:0005634	nucleus
0.36	GO:0070013	intracellular organelle lumen
0.35	GO:0044446	intracellular organelle part
0.34	GO:0034708	methyltransferase complex
0.34	GO:0005667	transcription factor complex
0.34	GO:0005694	chromosome
0.34	GO:1904949	ATPase complex
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:3.1.1

GO:0016298

tr|T1FR09|T1FR09_HELRO
Uncharacterized protein
Search

0.11	Putative conserved proteinconserved protein (Fragment)

0.66	GO:0009116	nucleoside metabolic process
0.45	GO:0042981	regulation of apoptotic process
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:0010468	regulation of gene expression

0.35	GO:0008270	zinc ion binding
0.35	GO:0016874	ligase activity
0.33	GO:0003700	DNA binding transcription factor activity

0.30

GO:0044425

membrane part

0.35

GO:0016874

tr|T1FR10|T1FR10_HELRO
Uncharacterized protein
Search

0.36	GO:0019538	protein metabolic process
0.35	GO:0043412	macromolecule modification
0.35	GO:0016310	phosphorylation
0.33	GO:0044260	cellular macromolecule metabolic process

0.37	GO:0004252	serine-type endopeptidase activity
0.36	GO:0004672	protein kinase activity
0.35	GO:0003676	nucleic acid binding
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0097367	carbohydrate derivative binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.77

GO:0008023

transcription elongation factor complex

0.37

GO:0004252

tr|T1FR11|T1FR11_HELRO
Solute carrier organic anion transporter family member
Search

0.33	Solute carrier organic anion transporter family member

0.55	GO:0055085	transmembrane transport
0.54	GO:0006811	ion transport
0.43	GO:0071702	organic substance transport
0.39	GO:1901998	toxin transport
0.39	GO:0010876	lipid localization
0.37	GO:0042886	amide transport
0.36	GO:0070327	thyroid hormone transport

0.56	GO:0005215	transporter activity
0.33	GO:0030246	carbohydrate binding

0.52	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

tr|T1FR12|T1FR12_HELRO
Uncharacterized protein
Search

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0060480	lung goblet cell differentiation
0.54	GO:0060576	intestinal epithelial cell development
0.54	GO:0010455	positive regulation of cell fate commitment
0.53	GO:0010454	negative regulation of cell fate commitment
0.50	GO:0043065	positive regulation of apoptotic process
0.47	GO:1902680	positive regulation of RNA biosynthetic process
0.47	GO:1902679	negative regulation of RNA biosynthetic process

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity

0.58

GO:0005634

nucleus

tr|T1FR13|T1FR13_HELRO
Uncharacterized protein
Search

tr|T1FR14|T1FR14_HELRO
Uncharacterized protein
Search

tr|T1FR15|T1FR15_HELRO
Uncharacterized protein
Search

0.80	GO:0060079	excitatory postsynaptic potential
0.77	GO:0035235	ionotropic glutamate receptor signaling pathway
0.58	GO:0006811	ion transport
0.54	GO:0072375	medium-term memory
0.53	GO:0050975	sensory perception of touch
0.52	GO:0007616	long-term memory
0.50	GO:0055085	transmembrane transport
0.36	GO:0035249	synaptic transmission, glutamatergic
0.36	GO:0007274	neuromuscular synaptic transmission
0.36	GO:0030510	regulation of BMP signaling pathway

0.82	GO:0005234	extracellularly glutamate-gated ion channel activity
0.77	GO:0004970	ionotropic glutamate receptor activity
0.50	GO:0099094	ligand-gated cation channel activity
0.48	GO:0022843	voltage-gated cation channel activity
0.35	GO:0005262	calcium channel activity

0.78	GO:0098794	postsynapse
0.69	GO:0097060	synaptic membrane
0.65	GO:0030054	cell junction
0.52	GO:0008328	ionotropic glutamate receptor complex
0.36	GO:0031594	neuromuscular junction
0.33	GO:0043226	organelle
0.32	GO:0005622	intracellular

tr|T1FR16|T1FR16_HELRO
Uncharacterized protein
Search

0.56	Nonsense-mediated mRNA decay protein 2

0.55	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.53	GO:0031100	animal organ regeneration
0.51	GO:0001889	liver development
0.41	GO:0007274	neuromuscular synaptic transmission
0.40	GO:0050808	synapse organization
0.36	GO:0016246	RNA interference
0.36	GO:0035195	gene silencing by miRNA
0.36	GO:0006986	response to unfolded protein
0.34	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.34	GO:0051028	mRNA transport

0.59	GO:0003723	RNA binding
0.50	GO:0042162	telomeric DNA binding
0.33	GO:0005515	protein binding

0.54	GO:0035145	exon-exon junction complex
0.49	GO:0036464	cytoplasmic ribonucleoprotein granule
0.45	GO:0005829	cytosol
0.45	GO:0005844	polysome
0.36	GO:0048471	perinuclear region of cytoplasm
0.30	GO:0016020	membrane

tr|T1FR17|T1FR17_HELRO
Uncharacterized protein
Search

CTNNB1

0.94	Catenin (cadherin-associated protein), beta 1

0.85	GO:0034333	adherens junction assembly
0.61	GO:0007165	signal transduction
0.53	GO:1904499	regulation of chromatin-mediated maintenance of transcription
0.53	GO:1904793	regulation of euchromatin binding
0.53	GO:0072054	renal outer medulla development
0.53	GO:0072053	renal inner medulla development
0.53	GO:0003340	negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
0.53	GO:0061198	fungiform papilla formation
0.52	GO:0070602	regulation of centromeric sister chromatid cohesion
0.52	GO:0045976	negative regulation of mitotic cell cycle, embryonic

0.64	GO:0004871	signal transducer activity
0.54	GO:0045294	alpha-catenin binding
0.52	GO:0001105	RNA polymerase II transcription coactivator activity
0.51	GO:0019903	protein phosphatase binding
0.51	GO:0045296	cadherin binding
0.51	GO:0070411	I-SMAD binding
0.50	GO:0030331	estrogen receptor binding
0.50	GO:0097718	disordered domain specific binding
0.49	GO:0001102	RNA polymerase II activating transcription factor binding
0.49	GO:0070491	repressing transcription factor binding

0.55	GO:0016342	catenin complex
0.53	GO:1990907	beta-catenin-TCF complex
0.52	GO:0034750	Scrib-APC-beta-catenin complex
0.52	GO:0071664	catenin-TCF7L2 complex
0.51	GO:1990909	Wnt signalosome
0.51	GO:0005913	cell-cell adherens junction
0.51	GO:0016600	flotillin complex
0.51	GO:0031528	microvillus membrane
0.51	GO:0030877	beta-catenin destruction complex
0.50	GO:0016328	lateral plasma membrane

tr|T1FR18|T1FR18_HELRO
POU domain protein
Search

0.63	GO:0006366	transcription by RNA polymerase II
0.59	GO:0007275	multicellular organism development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.39	GO:0031099	regeneration

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding

0.61

GO:0005634

nucleus

tr|T1FR19|T1FR19_HELRO
Uncharacterized protein
Search

tr|T1FR20|T1FR20_HELRO
Uncharacterized protein
Search

tr|T1FR21|T1FR21_HELRO
Uncharacterized protein
Search

tr|T1FR22|T1FR22_HELRO
Uncharacterized protein
Search

tr|T1FR23|T1FR23_HELRO
Uncharacterized protein
Search

tr|T1FR24|T1FR24_HELRO
Uncharacterized protein
Search

0.45	GO:0099120	socially cooperative development
0.42	GO:0098630	aggregation of unicellular organisms
0.42	GO:0036211	protein modification process
0.41	GO:0031158	negative regulation of aggregate size involved in sorocarp development
0.40	GO:0048518	positive regulation of biological process
0.40	GO:0044267	cellular protein metabolic process
0.40	GO:0090419	negative regulation of transcription involved in G2/M transition of mitotic cell cycle
0.40	GO:0009267	cellular response to starvation
0.40	GO:0006366	transcription by RNA polymerase II
0.40	GO:2000221	negative regulation of pseudohyphal growth

0.40	GO:0140110	transcription regulator activity
0.40	GO:0004672	protein kinase activity
0.40	GO:0051267	CP2 mannose-ethanolamine phosphotransferase activity
0.39	GO:0097367	carbohydrate derivative binding
0.39	GO:0008144	drug binding
0.39	GO:0030554	adenyl nucleotide binding
0.39	GO:0017056	structural constituent of nuclear pore
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0001085	RNA polymerase II transcription factor binding
0.38	GO:0045182	translation regulator activity

0.41	GO:0020008	rhoptry
0.39	GO:0044451	nucleoplasm part
0.38	GO:0055029	nuclear DNA-directed RNA polymerase complex
0.37	GO:0030176	integral component of endoplasmic reticulum membrane
0.37	GO:0043234	protein complex
0.36	GO:0005829	cytosol
0.35	GO:0005576	extracellular region

tr|T1FR25|T1FR25_HELRO
Uncharacterized protein
Search

tr|T1FR26|T1FR26_HELRO
Uncharacterized protein
Search

tr|T1FR27|T1FR27_HELRO
Uncharacterized protein
Search

0.73	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.45	GO:0070932	histone H3 deacetylation
0.44	GO:0048015	phosphatidylinositol-mediated signaling
0.42	GO:0007399	nervous system development
0.41	GO:0006400	tRNA modification
0.41	GO:0046854	phosphatidylinositol phosphorylation
0.40	GO:0007267	cell-cell signaling
0.40	GO:0006468	protein phosphorylation
0.39	GO:1903506	regulation of nucleic acid-templated transcription
0.39	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.66	GO:0005509	calcium ion binding
0.46	GO:0008193	tRNA guanylyltransferase activity
0.45	GO:0032041	NAD-dependent histone deacetylase activity (H3-K14 specific)
0.43	GO:0035091	phosphatidylinositol binding
0.40	GO:0000287	magnesium ion binding
0.40	GO:0004672	protein kinase activity
0.38	GO:0005315	inorganic phosphate transmembrane transporter activity
0.38	GO:0033830	Skp1-protein-hydroxyproline N-acetylglucosaminyltransferase activity
0.37	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0008144	drug binding

0.53	GO:0005886	plasma membrane
0.40	GO:0005634	nucleus
0.32	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.46

GO:0008193

tr|T1FR28|T1FR28_HELRO
Uncharacterized protein
Search

tr|T1FR29|T1FR29_HELRO
Uncharacterized protein
Search

tr|T1FR30|T1FR30_HELRO
Uncharacterized protein
Search

0.62	GO:0019050	suppression by virus of host apoptotic process
0.49	GO:0007219	Notch signaling pathway
0.46	GO:0030154	cell differentiation
0.46	GO:0007275	multicellular organism development
0.44	GO:0050793	regulation of developmental process
0.39	GO:1903506	regulation of nucleic acid-templated transcription
0.39	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.39	GO:0010468	regulation of gene expression
0.39	GO:0050790	regulation of catalytic activity
0.37	GO:0060026	convergent extension

0.69	GO:0005509	calcium ion binding
0.42	GO:0004872	receptor activity
0.40	GO:0030695	GTPase regulator activity
0.37	GO:0005201	extracellular matrix structural constituent
0.36	GO:0043565	sequence-specific DNA binding
0.35	GO:0003700	DNA binding transcription factor activity
0.35	GO:0008234	cysteine-type peptidase activity

0.44	GO:0005576	extracellular region
0.37	GO:0009986	cell surface
0.35	GO:0005634	nucleus
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.35

GO:0008234

tr|T1FR31|T1FR31_HELRO
Uncharacterized protein
Search

0.58	Collagen type XIII alpha 1 chain

0.46	GO:0035987	endodermal cell differentiation
0.44	GO:0070208	protein heterotrimerization
0.43	GO:0071230	cellular response to amino acid stimulus
0.40	GO:0048731	system development
0.40	GO:0048519	negative regulation of biological process
0.39	GO:0052548	regulation of endopeptidase activity
0.39	GO:0051346	negative regulation of hydrolase activity
0.39	GO:0030198	extracellular matrix organization
0.39	GO:0007155	cell adhesion
0.39	GO:2000026	regulation of multicellular organismal development

0.61	GO:0005201	extracellular matrix structural constituent
0.46	GO:0048407	platelet-derived growth factor binding
0.40	GO:0004867	serine-type endopeptidase inhibitor activity
0.36	GO:0043394	proteoglycan binding
0.36	GO:0008201	heparin binding
0.36	GO:0042302	structural constituent of cuticle
0.33	GO:0042802	identical protein binding
0.33	GO:0005044	scavenger receptor activity
0.33	GO:0030246	carbohydrate binding
0.33	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.67	GO:0005581	collagen trimer
0.53	GO:0031012	extracellular matrix
0.43	GO:0042383	sarcolemma
0.42	GO:0005615	extracellular space
0.38	GO:0099080	supramolecular complex
0.35	GO:0005765	lysosomal membrane
0.35	GO:1903561	extracellular vesicle
0.34	GO:0030056	hemidesmosome
0.34	GO:0005788	endoplasmic reticulum lumen
0.34	GO:0005634	nucleus

0.33

GO:0004553

tr|T1FR32|T1FR32_HELRO
Uncharacterized protein
Search

tr|T1FR33|T1FR33_HELRO
Uncharacterized protein
Search

tr|T1FR34|T1FR34_HELRO
Uncharacterized protein
Search

tr|T1FR35|T1FR35_HELRO
Uncharacterized protein
Search

tr|T1FR36|T1FR36_HELRO
Uncharacterized protein
Search

tr|T1FR37|T1FR37_HELRO
Uncharacterized protein
Search

MYO5B

0.76	Unconventional myosin-Va

0.74	GO:0007018	microtubule-based movement
0.45	GO:0099089	establishment of endoplasmic reticulum localization to postsynapse
0.45	GO:0051648	vesicle localization
0.44	GO:0031585	regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
0.44	GO:0031987	locomotion involved in locomotory behavior
0.43	GO:0099515	actin filament-based transport
0.43	GO:0030318	melanocyte differentiation
0.43	GO:0030073	insulin secretion
0.43	GO:0042759	long-chain fatty acid biosynthetic process
0.43	GO:0042438	melanin biosynthetic process

0.77	GO:0051015	actin filament binding
0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0017137	Rab GTPase binding
0.44	GO:0000146	microfilament motor activity
0.43	GO:0097718	disordered domain specific binding

0.77	GO:0016459	myosin complex
0.43	GO:0032593	insulin-responsive compartment
0.43	GO:0032433	filopodium tip
0.43	GO:0055037	recycling endosome
0.43	GO:0035371	microtubule plus-end
0.42	GO:0042470	melanosome
0.42	GO:0042641	actomyosin
0.42	GO:0001750	photoreceptor outer segment
0.42	GO:0043025	neuronal cell body
0.42	GO:0001726	ruffle

0.33

GO:0016747

tr|T1FR38|T1FR38_HELRO
Uncharacterized protein
Search

0.47	GO:0016569	covalent chromatin modification
0.46	GO:0035066	positive regulation of histone acetylation
0.46	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle
0.44	GO:0008285	negative regulation of cell proliferation
0.43	GO:2001141	regulation of RNA biosynthetic process
0.43	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.43	GO:0010468	regulation of gene expression
0.42	GO:0051254	positive regulation of RNA metabolic process
0.42	GO:0010557	positive regulation of macromolecule biosynthetic process
0.42	GO:0031328	positive regulation of cellular biosynthetic process

0.83	GO:0070577	lysine-acetylated histone binding
0.46	GO:0002039	p53 binding
0.45	GO:0003714	transcription corepressor activity
0.44	GO:0003713	transcription coactivator activity
0.43	GO:0044212	transcription regulatory region DNA binding
0.42	GO:0008134	transcription factor binding
0.41	GO:0015379	potassium:chloride symporter activity
0.38	GO:0030246	carbohydrate binding
0.34	GO:0046872	metal ion binding

0.42	GO:0005654	nucleoplasm
0.41	GO:0005829	cytosol
0.37	GO:0005887	integral component of plasma membrane

tr|T1FR39|T1FR39_HELRO
Uncharacterized protein
Search

0.73	GO:0006914	autophagy
0.62	GO:0007033	vacuole organization
0.56	GO:0070925	organelle assembly
0.49	GO:0048203	vesicle targeting, trans-Golgi to endosome
0.46	GO:0061726	mitochondrion disassembly
0.44	GO:0006497	protein lipidation
0.42	GO:0034613	cellular protein localization
0.34	GO:0034599	cellular response to oxidative stress
0.34	GO:0036498	IRE1-mediated unfolded protein response
0.34	GO:0061365	positive regulation of triglyceride lipase activity

0.78	GO:0032266	phosphatidylinositol-3-phosphate binding
0.68	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding
0.48	GO:0050681	androgen receptor binding
0.48	GO:0030331	estrogen receptor binding
0.35	GO:0070273	phosphatidylinositol-4-phosphate binding
0.33	GO:0010314	phosphatidylinositol-5-phosphate binding
0.33	GO:0043130	ubiquitin binding
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding

0.66	GO:0000407	phagophore assembly site
0.48	GO:0000421	autophagosome membrane
0.45	GO:0005802	trans-Golgi network
0.45	GO:0010008	endosome membrane
0.45	GO:0005829	cytosol
0.43	GO:0019898	extrinsic component of membrane
0.37	GO:0000329	fungal-type vacuole membrane
0.35	GO:0030136	clathrin-coated vesicle
0.34	GO:0005856	cytoskeleton
0.33	GO:0045335	phagocytic vesicle

0.32

EC:2.4.2.31

GO:0003956

tr|T1FR40|T1FR40_HELRO
Uncharacterized protein
Search

0.46	GO:0016310	phosphorylation
0.43	GO:0036211	protein modification process
0.41	GO:0065007	biological regulation
0.41	GO:0044267	cellular protein metabolic process
0.41	GO:0016042	lipid catabolic process
0.38	GO:0043326	chemotaxis to folate
0.38	GO:0043327	chemotaxis to cAMP
0.37	GO:0034227	tRNA thio-modification
0.37	GO:0006886	intracellular protein transport
0.37	GO:0035070	salivary gland histolysis

0.51	GO:0000829	inositol heptakisphosphate kinase activity
0.44	GO:0004672	protein kinase activity
0.41	GO:0030554	adenyl nucleotide binding
0.41	GO:0097367	carbohydrate derivative binding
0.41	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0008144	drug binding
0.40	GO:0098772	molecular function regulator
0.39	GO:0003700	DNA binding transcription factor activity
0.38	GO:0003723	RNA binding
0.37	GO:0016787	hydrolase activity

0.38	GO:0005634	nucleus
0.37	GO:0030131	clathrin adaptor complex
0.37	GO:0005881	cytoplasmic microtubule
0.37	GO:0020011	apicoplast
0.36	GO:0005815	microtubule organizing center
0.36	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0070013	intracellular organelle lumen
0.35	GO:1902494	catalytic complex
0.34	GO:0005794	Golgi apparatus
0.34	GO:0000785	chromatin

0.37	EC:3	GO:0016787
0.36	KEGG:R03361	GO:0004430

tr|T1FR41|T1FR41_HELRO
Uncharacterized protein
Search

0.53	GO:0046872	metal ion binding
0.37	GO:0030246	carbohydrate binding
0.34	GO:0003676	nucleic acid binding

0.30

GO:0044425

membrane part

tr|T1FR42|T1FR42_HELRO
Uncharacterized protein
Search

tr|T1FR43|T1FR43_HELRO
Uncharacterized protein
Search

NSF

0.78	N-ethylmaleimide-sensitive factor a

0.47	GO:0001921	positive regulation of receptor recycling
0.44	GO:0060439	trachea morphogenesis
0.44	GO:0045732	positive regulation of protein catabolic process
0.44	GO:0008582	regulation of synaptic growth at neuromuscular junction
0.44	GO:0007274	neuromuscular synaptic transmission
0.43	GO:0006813	potassium ion transport
0.42	GO:0051641	cellular localization
0.41	GO:0015031	protein transport
0.40	GO:0048893	afferent axon development in lateral line nerve
0.40	GO:0048929	efferent axon development in posterior lateral line nerve

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0017075	syntaxin-1 binding
0.47	GO:0035255	ionotropic glutamate receptor binding
0.46	GO:0019901	protein kinase binding
0.46	GO:0030165	PDZ domain binding
0.43	GO:0032403	protein complex binding
0.41	GO:0042623	ATPase activity, coupled

0.47	GO:0043209	myelin sheath
0.41	GO:0005829	cytosol
0.38	GO:0005765	lysosomal membrane
0.37	GO:0005886	plasma membrane
0.36	GO:0043198	dendritic shaft
0.36	GO:0044456	synapse part
0.36	GO:0005576	extracellular region
0.36	GO:0032279	asymmetric synapse
0.35	GO:0005795	Golgi stack
0.35	GO:0031982	vesicle

0.34	EC:3.1.1 EC:3.1.1.1	GO:0052689
0.34	KEGG:R00630	GO:0052689

tr|T1FR44|T1FR44_HELRO
Uncharacterized protein
Search

0.83	GO:0006003	fructose 2,6-bisphosphate metabolic process
0.83	GO:0006000	fructose metabolic process
0.74	GO:0046835	carbohydrate phosphorylation
0.42	GO:0034227	tRNA thio-modification
0.41	GO:0032447	protein urmylation
0.41	GO:0002098	tRNA wobble uridine modification
0.35	GO:0016311	dephosphorylation
0.34	GO:0007420	brain development

0.84	GO:0003873	6-phosphofructo-2-kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0000049	tRNA binding
0.38	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity
0.37	GO:0016779	nucleotidyltransferase activity
0.33	GO:0016746	transferase activity, transferring acyl groups

0.38	GO:0005654	nucleoplasm
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.84	EC:2.7.1.105	GO:0003873
0.84	KEGG:R02732	GO:0003873

tr|T1FR45|T1FR45_HELRO
Uncharacterized protein
Search

0.55	E3 ubiquitin-protein ligase UBR4

0.51	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.35	GO:0043312	neutrophil degranulation
0.33	GO:0016032	viral process

0.60	GO:0008270	zinc ion binding
0.52	GO:0016874	ligase activity
0.47	GO:0004842	ubiquitin-protein transferase activity
0.37	GO:0005516	calmodulin binding

0.49	GO:0005813	centrosome
0.46	GO:0005654	nucleoplasm
0.45	GO:0005829	cytosol
0.35	GO:0101003	ficolin-1-rich granule membrane
0.35	GO:0035579	specific granule membrane
0.35	GO:0070821	tertiary granule membrane
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.52	EC:6	GO:0016874
0.47	KEGG:R03876	GO:0004842

tr|T1FR46|T1FR46_HELRO
Uncharacterized protein
Search

0.53

GO:0042787

protein ubiquitination involved in ubiquitin-dependent protein catabolic process

0.63	GO:0008270	zinc ion binding
0.49	GO:0004842	ubiquitin-protein transferase activity
0.47	GO:0016874	ligase activity
0.33	GO:0005516	calmodulin binding

0.51	GO:0005813	centrosome
0.47	GO:0005654	nucleoplasm
0.47	GO:0005829	cytosol
0.30	GO:0044425	membrane part

0.47	EC:6	GO:0016874
0.49	KEGG:R03876	GO:0004842

tr|T1FR47|T1FR47_HELRO
Uncharacterized protein
Search

0.44	GO:0006491	N-glycan processing
0.41	GO:0016567	protein ubiquitination
0.41	GO:0006364	rRNA processing
0.39	GO:0006508	proteolysis
0.37	GO:0006355	regulation of transcription, DNA-templated

0.43	GO:0003676	nucleic acid binding
0.43	GO:0008234	cysteine-type peptidase activity
0.41	GO:0004842	ubiquitin-protein transferase activity
0.40	GO:0005509	calcium ion binding
0.38	GO:0003700	DNA binding transcription factor activity

0.45	GO:0030688	preribosome, small subunit precursor
0.38	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.43	EC:3.4	GO:0008234
0.41	KEGG:R03876	GO:0004842

tr|T1FR48|T1FR48_HELRO
Uncharacterized protein
Search

0.48	GO:0006325	chromatin organization
0.45	GO:0006357	regulation of transcription by RNA polymerase II
0.43	GO:0018022	peptidyl-lysine methylation
0.42	GO:0005987	sucrose catabolic process
0.42	GO:2000219	positive regulation of invasive growth in response to glucose limitation
0.41	GO:0045893	positive regulation of transcription, DNA-templated
0.41	GO:2000877	negative regulation of oligopeptide transport
0.41	GO:0090089	regulation of dipeptide transport
0.41	GO:0045990	carbon catabolite regulation of transcription
0.40	GO:0048583	regulation of response to stimulus

0.47	GO:0000989	transcription factor activity, transcription factor binding
0.42	GO:0003676	nucleic acid binding
0.41	GO:0015616	DNA translocase activity
0.41	GO:0001102	RNA polymerase II activating transcription factor binding
0.40	GO:0003700	DNA binding transcription factor activity
0.40	GO:0019899	enzyme binding
0.38	GO:0008270	zinc ion binding
0.37	GO:0098772	molecular function regulator

0.47	GO:0005634	nucleus
0.44	GO:0031974	membrane-enclosed lumen
0.43	GO:0034708	methyltransferase complex
0.41	GO:0044446	intracellular organelle part
0.39	GO:0030123	AP-3 adaptor complex
0.39	GO:0017053	transcriptional repressor complex
0.39	GO:0032040	small-subunit processome
0.37	GO:0005829	cytosol
0.37	GO:0005694	chromosome
0.37	GO:1904949	ATPase complex

tr|T1FR49|T1FR49_HELRO
Uncharacterized protein
Search

tr|T1FR50|T1FR50_HELRO
Uncharacterized protein
Search

tr|T1FR51|T1FR51_HELRO
Uncharacterized protein
Search

tr|T1FR52|T1FR52_HELRO
Uncharacterized protein
Search

tr|T1FR53|T1FR53_HELRO
Uncharacterized protein
Search

0.46	GO:0006886	intracellular protein transport
0.45	GO:0016192	vesicle-mediated transport
0.41	GO:1905499	trichome papilla formation
0.40	GO:0010091	trichome branching
0.40	GO:0009911	positive regulation of flower development
0.40	GO:0010114	response to red light
0.40	GO:0010218	response to far red light
0.40	GO:0009867	jasmonic acid mediated signaling pathway
0.40	GO:0009585	red, far-red light phototransduction
0.39	GO:0050832	defense response to fungus

0.38	GO:0003743	translation initiation factor activity
0.38	GO:0008092	cytoskeletal protein binding
0.37	GO:0000175	3'-5'-exoribonuclease activity
0.37	GO:0003700	DNA binding transcription factor activity
0.36	GO:0003777	microtubule motor activity
0.36	GO:0003682	chromatin binding
0.35	GO:0003677	DNA binding
0.35	GO:0008270	zinc ion binding
0.34	GO:0004519	endonuclease activity
0.34	GO:0032559	adenyl ribonucleotide binding

0.53	GO:0030124	AP-4 adaptor complex
0.38	GO:0016592	mediator complex
0.37	GO:0000932	P-body
0.37	GO:0000178	exosome (RNase complex)
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.37

EC:3.1.13

GO:0000175

tr|T1FR54|T1FR54_HELRO
Uncharacterized protein
Search

tr|T1FR55|T1FR55_HELRO
Uncharacterized protein
Search

tr|T1FR56|T1FR56_HELRO
Uncharacterized protein
Search

0.63	GO:0009116	nucleoside metabolic process
0.38	GO:0006468	protein phosphorylation
0.37	GO:0006338	chromatin remodeling
0.37	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
0.36	GO:0006413	translational initiation
0.35	GO:0006281	DNA repair
0.34	GO:0006508	proteolysis
0.34	GO:0006351	transcription, DNA-templated
0.34	GO:0006355	regulation of transcription, DNA-templated

0.39	GO:0043531	ADP binding
0.38	GO:0004672	protein kinase activity
0.36	GO:0003777	microtubule motor activity
0.36	GO:0005524	ATP binding
0.36	GO:0003743	translation initiation factor activity
0.36	GO:0004222	metalloendopeptidase activity
0.35	GO:0004888	transmembrane signaling receptor activity
0.35	GO:0016887	ATPase activity
0.34	GO:0003700	DNA binding transcription factor activity
0.34	GO:0046872	metal ion binding

0.37	GO:0005871	kinesin complex
0.37	GO:0031011	Ino80 complex
0.34	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.36

GO:0004222

tr|T1FR57|T1FR57_HELRO
Uncharacterized protein
Search

tr|T1FR58|T1FR58_HELRO
Uncharacterized protein
Search

tr|T1FR59|T1FR59_HELRO
Uncharacterized protein
Search

0.62	GO:0005730	nucleolus
0.59	GO:0005829	cytosol

tr|T1FR60|T1FR60_HELRO
Uncharacterized protein
Search

0.44	GO:0006357	regulation of transcription by RNA polymerase II
0.44	GO:0090114	COPII-coated vesicle budding
0.43	GO:0048207	vesicle targeting, rough ER to cis-Golgi
0.43	GO:0006901	vesicle coating
0.42	GO:0048569	post-embryonic animal organ development
0.42	GO:0002165	instar larval or pupal development
0.42	GO:0045893	positive regulation of transcription, DNA-templated
0.41	GO:0030707	ovarian follicle cell development
0.41	GO:0007552	metamorphosis
0.41	GO:0009886	post-embryonic animal morphogenesis

0.44	GO:0008270	zinc ion binding
0.42	GO:0140110	transcription regulator activity
0.42	GO:0005515	protein binding
0.41	GO:0003676	nucleic acid binding
0.41	GO:0004842	ubiquitin-protein transferase activity
0.39	GO:0005509	calcium ion binding
0.37	GO:0005198	structural molecule activity
0.37	GO:0016874	ligase activity
0.37	GO:0004476	mannose-6-phosphate isomerase activity
0.37	GO:0050825	ice binding

0.47	GO:0005634	nucleus
0.42	GO:0044446	intracellular organelle part
0.41	GO:0070013	intracellular organelle lumen
0.41	GO:0005794	Golgi apparatus
0.41	GO:0098588	bounding membrane of organelle
0.39	GO:0005783	endoplasmic reticulum
0.39	GO:1990234	transferase complex
0.38	GO:0005667	transcription factor complex
0.38	GO:0005700	polytene chromosome
0.38	GO:1905368	peptidase complex

0.37	EC:6	GO:0016874
0.41	KEGG:R03876	GO:0004842

tr|T1FR61|T1FR61_HELRO
Uncharacterized protein
Search

0.44	GO:0006030	chitin metabolic process
0.43	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle
0.39	GO:0099120	socially cooperative development
0.39	GO:0001708	cell fate specification
0.39	GO:0006352	DNA-templated transcription, initiation
0.38	GO:0006357	regulation of transcription by RNA polymerase II
0.38	GO:0071456	cellular response to hypoxia
0.37	GO:0019954	asexual reproduction
0.37	GO:0006888	ER to Golgi vesicle-mediated transport
0.37	GO:0006662	glycerol ether metabolic process

0.44	GO:0003676	nucleic acid binding
0.44	GO:0008061	chitin binding
0.41	GO:0008270	zinc ion binding
0.41	GO:0046983	protein dimerization activity
0.37	GO:0016491	oxidoreductase activity
0.37	GO:0032550	purine ribonucleoside binding
0.37	GO:0019001	guanyl nucleotide binding
0.37	GO:0003777	microtubule motor activity
0.37	GO:0042302	structural constituent of cuticle
0.36	GO:0140096	catalytic activity, acting on a protein

0.50	GO:0005634	nucleus
0.44	GO:0005667	transcription factor complex
0.42	GO:0044446	intracellular organelle part
0.42	GO:0005576	extracellular region
0.42	GO:0031974	membrane-enclosed lumen
0.40	GO:0031248	protein acetyltransferase complex
0.40	GO:0000428	DNA-directed RNA polymerase complex
0.39	GO:1905368	peptidase complex
0.38	GO:0005694	chromosome
0.37	GO:0030134	COPII-coated ER to Golgi transport vesicle

0.37

GO:0016491

tr|T1FR62|T1FR62_HELRO
Uncharacterized protein
Search

tr|T1FR63|T1FR63_HELRO
Uncharacterized protein
Search

0.41	GO:0046854	phosphatidylinositol phosphorylation
0.40	GO:0045924	regulation of female receptivity
0.40	GO:0008049	male courtship behavior
0.40	GO:0036211	protein modification process
0.39	GO:0010556	regulation of macromolecule biosynthetic process
0.39	GO:0031326	regulation of cellular biosynthetic process
0.39	GO:0051171	regulation of nitrogen compound metabolic process
0.39	GO:0080090	regulation of primary metabolic process
0.39	GO:0048813	dendrite morphogenesis
0.39	GO:0009890	negative regulation of biosynthetic process

0.43	GO:0016307	phosphatidylinositol phosphate kinase activity
0.40	GO:0005509	calcium ion binding
0.39	GO:0005515	protein binding
0.39	GO:0004722	protein serine/threonine phosphatase activity
0.39	GO:0019789	SUMO transferase activity
0.39	GO:0140110	transcription regulator activity
0.38	GO:0008144	drug binding
0.38	GO:0030554	adenyl nucleotide binding
0.38	GO:0043168	anion binding
0.38	GO:0000976	transcription regulatory region sequence-specific DNA binding

0.40	GO:0005634	nucleus
0.38	GO:0030015	CCR4-NOT core complex
0.38	GO:0044446	intracellular organelle part
0.38	GO:0000932	P-body
0.36	GO:0070013	intracellular organelle lumen
0.36	GO:0031090	organelle membrane
0.36	GO:0034751	aryl hydrocarbon receptor complex
0.35	GO:0005739	mitochondrion
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0005794	Golgi apparatus

0.43

GO:0016307

tr|T1FR64|T1FR64_HELRO
Uncharacterized protein
Search

0.42	GO:0035171	lamellocyte differentiation
0.42	GO:0045612	positive regulation of hemocyte differentiation
0.42	GO:0060288	formation of a compartment boundary
0.42	GO:0045316	negative regulation of compound eye photoreceptor development
0.42	GO:0060289	compartment boundary maintenance
0.42	GO:0035172	hemocyte proliferation
0.42	GO:0042689	regulation of crystal cell differentiation
0.42	GO:0048052	R1/R6 cell differentiation
0.41	GO:0045614	negative regulation of plasmatocyte differentiation
0.41	GO:0035203	regulation of lamellocyte differentiation

0.69	GO:0005509	calcium ion binding
0.39	GO:0003682	chromatin binding
0.37	GO:0005044	scavenger receptor activity

0.41	GO:0035003	subapical complex
0.39	GO:0030139	endocytic vesicle
0.39	GO:0005770	late endosome
0.39	GO:0005912	adherens junction
0.39	GO:0005576	extracellular region
0.39	GO:0005764	lysosome
0.38	GO:0009986	cell surface
0.36	GO:0005634	nucleus
0.35	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

tr|T1FR65|T1FR65_HELRO
Uncharacterized protein
Search

0.44	GO:0009405	pathogenesis
0.44	GO:0006334	nucleosome assembly
0.42	GO:0000453	enzyme-directed rRNA 2'-O-methylation
0.41	GO:0006508	proteolysis
0.40	GO:0043632	modification-dependent macromolecule catabolic process
0.40	GO:0061564	axon development
0.40	GO:0044257	cellular protein catabolic process
0.40	GO:0070647	protein modification by small protein conjugation or removal
0.40	GO:0046160	heme a metabolic process
0.40	GO:0048033	heme o metabolic process

0.43	GO:0070039	rRNA (guanosine-2'-O-)-methyltransferase activity
0.42	GO:0070011	peptidase activity, acting on L-amino acid peptides
0.41	GO:0101005	ubiquitinyl hydrolase activity
0.40	GO:0008495	protoheme IX farnesyltransferase activity
0.39	GO:0008484	sulfuric ester hydrolase activity
0.38	GO:0016758	transferase activity, transferring hexosyl groups
0.38	GO:0017171	serine hydrolase activity
0.37	GO:0003723	RNA binding
0.37	GO:0008270	zinc ion binding
0.35	GO:0003677	DNA binding

0.48	GO:0070701	mucus layer
0.42	GO:0043231	intracellular membrane-bounded organelle
0.42	GO:0005883	neurofilament
0.39	GO:0009986	cell surface
0.36	GO:0031967	organelle envelope
0.36	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

0.40

EC:2.5.1

GO:0008495

tr|T1FR66|T1FR66_HELRO
Uncharacterized protein
Search

tr|T1FR67|T1FR67_HELRO
Uncharacterized protein
Search

tr|T1FR68|T1FR68_HELRO
Uncharacterized protein
Search

tr|T1FR69|T1FR69_HELRO
Uncharacterized protein
Search

tr|T1FR70|T1FR70_HELRO
Uncharacterized protein
Search

tr|T1FR71|T1FR71_HELRO
Uncharacterized protein
Search

0.57	GO:0007155	cell adhesion
0.45	GO:0006030	chitin metabolic process
0.42	GO:0007018	microtubule-based movement

0.64	GO:0008022	protein C-terminus binding
0.44	GO:0008061	chitin binding
0.42	GO:0003777	microtubule motor activity
0.38	GO:0008270	zinc ion binding

0.69	GO:0043220	Schmidt-Lanterman incisure
0.67	GO:0016327	apicolateral plasma membrane
0.63	GO:0016324	apical plasma membrane
0.63	GO:0005923	bicellular tight junction
0.57	GO:0031410	cytoplasmic vesicle
0.41	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

tr|T1FR72|T1FR72_HELRO
Uncharacterized protein
Search

0.48	GO:0055114	oxidation-reduction process
0.43	GO:0070544	histone H3-K36 demethylation
0.38	GO:0015031	protein transport
0.37	GO:0032259	methylation
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:0010468	regulation of gene expression

0.49	GO:0016491	oxidoreductase activity
0.48	GO:0046872	metal ion binding
0.42	GO:0032452	histone demethylase activity
0.37	GO:0003700	DNA binding transcription factor activity
0.37	GO:0008168	methyltransferase activity
0.36	GO:0003677	DNA binding

0.42	GO:0030123	AP-3 adaptor complex
0.41	GO:0034399	nuclear periphery
0.30	GO:0016021	integral component of membrane

0.49

GO:0016491

tr|T1FR73|T1FR73_HELRO
Uncharacterized protein
Search

tr|T1FR74|T1FR74_HELRO
Uncharacterized protein
Search

0.44	GO:0007018	microtubule-based movement
0.39	GO:0031154	culmination involved in sorocarp development
0.38	GO:0006886	intracellular protein transport
0.38	GO:0016192	vesicle-mediated transport
0.38	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA
0.37	GO:0016570	histone modification
0.36	GO:0018393	internal peptidyl-lysine acetylation
0.36	GO:0007275	multicellular organism development
0.36	GO:0007099	centriole replication
0.35	GO:0006368	transcription elongation from RNA polymerase II promoter

0.60	GO:0030145	manganese ion binding
0.50	GO:0003723	RNA binding
0.47	GO:0016787	hydrolase activity
0.44	GO:0008017	microtubule binding
0.39	GO:0017076	purine nucleotide binding
0.39	GO:0097367	carbohydrate derivative binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0008144	drug binding
0.37	GO:0004402	histone acetyltransferase activity
0.36	GO:0046983	protein dimerization activity

0.41	GO:0030123	AP-3 adaptor complex
0.38	GO:0015630	microtubule cytoskeleton
0.37	GO:0044430	cytoskeletal part
0.37	GO:0000932	P-body
0.37	GO:0020011	apicoplast
0.36	GO:0005634	nucleus
0.36	GO:0099512	supramolecular fiber
0.36	GO:0030135	coated vesicle
0.35	GO:0000428	DNA-directed RNA polymerase complex
0.35	GO:0048786	presynaptic active zone

0.47

GO:0016787

tr|T1FR75|T1FR75_HELRO
Uncharacterized protein
Search

tr|T1FR76|T1FR76_HELRO
Uncharacterized protein
Search

0.27	Cathepsin L protease

0.61	GO:0006508	proteolysis
0.40	GO:0044257	cellular protein catabolic process
0.38	GO:0097067	cellular response to thyroid hormone stimulus
0.38	GO:0030574	collagen catabolic process
0.37	GO:0002250	adaptive immune response
0.36	GO:0010839	negative regulation of keratinocyte proliferation
0.36	GO:0046697	decidualization
0.36	GO:0031069	hair follicle morphogenesis
0.35	GO:2000249	regulation of actin cytoskeleton reorganization
0.35	GO:0071888	macrophage apoptotic process

0.72	GO:0008234	cysteine-type peptidase activity
0.39	GO:0004175	endopeptidase activity
0.39	GO:0097655	serpin family protein binding
0.38	GO:0042393	histone binding
0.38	GO:0001968	fibronectin binding
0.37	GO:0043394	proteoglycan binding
0.37	GO:0005518	collagen binding
0.34	GO:0004180	carboxypeptidase activity
0.34	GO:0017171	serine hydrolase activity
0.33	GO:0003747	translation release factor activity

0.43	GO:0005764	lysosome
0.41	GO:0005615	extracellular space
0.35	GO:0031410	cytoplasmic vesicle
0.34	GO:0045169	fusome
0.34	GO:0043233	organelle lumen
0.34	GO:0005634	nucleus
0.34	GO:1903561	extracellular vesicle
0.33	GO:0044446	intracellular organelle part
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.33	GO:0012505	endomembrane system

0.72

GO:0008234

tr|T1FR77|T1FR77_HELRO
Uncharacterized protein
Search

tr|T1FR78|T1FR78_HELRO
Uncharacterized protein
Search

tr|T1FR79|T1FR79_HELRO
Uncharacterized protein
Search

tr|T1FR80|T1FR80_HELRO
Uncharacterized protein
Search

0.73	GO:0032474	otolith morphogenesis
0.68	GO:0061371	determination of heart left/right asymmetry
0.64	GO:0060271	cilium assembly

0.52

GO:0003779

actin binding

0.35	GO:0005840	ribosome
0.30	GO:0044425	membrane part

tr|T1FR81|T1FR81_HELRO
Uncharacterized protein
Search

tr|T1FR82|T1FR82_HELRO
Uncharacterized protein
Search

0.20	Matrix metalloproteinase-9

0.61	GO:0006508	proteolysis
0.52	GO:0006954	inflammatory response
0.48	GO:0060022	hard palate development
0.39	GO:0010727	negative regulation of hydrogen peroxide metabolic process
0.39	GO:0001554	luteolysis
0.39	GO:0001542	ovulation from ovarian follicle
0.38	GO:0032461	positive regulation of protein oligomerization
0.38	GO:0051591	response to cAMP
0.38	GO:0001541	ovarian follicle development
0.37	GO:0097186	amelogenesis

0.70	GO:0004222	metalloendopeptidase activity
0.63	GO:0008270	zinc ion binding
0.40	GO:0016758	transferase activity, transferring hexosyl groups
0.35	GO:0004252	serine-type endopeptidase activity
0.34	GO:0016504	peptidase activator activity
0.32	GO:0003676	nucleic acid binding

0.74	GO:0031012	extracellular matrix
0.40	GO:0005789	endoplasmic reticulum membrane
0.39	GO:0005615	extracellular space
0.38	GO:0005886	plasma membrane
0.36	GO:0031225	anchored component of membrane
0.35	GO:0035579	specific granule membrane
0.34	GO:0009986	cell surface
0.30	GO:0016021	integral component of membrane

0.70

GO:0004222

tr|T1FR83|T1FR83_HELRO
Uncharacterized protein
Search

tr|T1FR84|T1FR84_HELRO
Uncharacterized protein
Search

tr|T1FR85|T1FR85_HELRO
Uncharacterized protein
Search

LOC106156405

0.60	Cys-loop ligand-gated ionic channel

0.61	GO:0007165	signal transduction
0.60	GO:0034220	ion transmembrane transport

0.76	GO:0005230	extracellular ligand-gated ion channel activity
0.70	GO:0099600	transmembrane receptor activity
0.65	GO:0038023	signaling receptor activity

0.30

GO:0031224

intrinsic component of membrane

tr|T1FR86|T1FR86_HELRO
Uncharacterized protein
Search

0.69	GO:0016192	vesicle-mediated transport
0.67	GO:0006886	intracellular protein transport
0.55	GO:1902774	late endosome to lysosome transport
0.51	GO:0090174	organelle membrane fusion
0.50	GO:0016050	vesicle organization
0.49	GO:0016197	endosomal transport
0.49	GO:0006914	autophagy
0.44	GO:0048066	developmental pigmentation
0.43	GO:0001654	eye development
0.33	GO:0008593	regulation of Notch signaling pathway

0.35	GO:0005515	protein binding
0.35	GO:0004491	methylmalonate-semialdehyde dehydrogenase (acylating) activity
0.33	GO:0102568	phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
0.33	GO:0102567	phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
0.32	GO:0004623	phospholipase A2 activity
0.31	GO:0046872	metal ion binding

0.53	GO:0030897	HOPS complex
0.52	GO:0005765	lysosomal membrane
0.51	GO:0031902	late endosome membrane
0.51	GO:0030123	AP-3 adaptor complex

0.35

EC:1.2.1.27

GO:0004491

tr|T1FR87|T1FR87_HELRO
Uncharacterized protein
Search

0.44	GO:0000398	mRNA splicing, via spliceosome
0.36	GO:0018108	peptidyl-tyrosine phosphorylation
0.33	GO:0035556	intracellular signal transduction
0.32	GO:0055114	oxidation-reduction process

0.58	GO:0003723	RNA binding
0.36	GO:0004713	protein tyrosine kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0051213	dioxygenase activity
0.32	GO:0008270	zinc ion binding
0.32	GO:0003677	DNA binding

0.55	GO:0019013	viral nucleocapsid
0.49	GO:0030529	intracellular ribonucleoprotein complex
0.43	GO:0005634	nucleus
0.33	GO:0005856	cytoskeleton
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.36

GO:0004713

tr|T1FR88|T1FR88_HELRO
Uncharacterized protein
Search

tr|T1FR89|T1FR89_HELRO
Uncharacterized protein
Search

0.64	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.53	GO:0000712	resolution of meiotic recombination intermediates
0.53	GO:0031573	intra-S DNA damage checkpoint
0.52	GO:0044818	mitotic G2/M transition checkpoint
0.51	GO:0072429	response to intra-S DNA damage checkpoint signaling
0.50	GO:0006308	DNA catabolic process
0.49	GO:0000724	double-strand break repair via homologous recombination
0.47	GO:0031572	G2 DNA damage checkpoint
0.47	GO:0031297	replication fork processing
0.46	GO:0010520	regulation of reciprocal meiotic recombination

0.64	GO:0004518	nuclease activity
0.55	GO:0003677	DNA binding
0.46	GO:0140097	catalytic activity, acting on DNA
0.35	GO:0046872	metal ion binding
0.34	GO:0035091	phosphatidylinositol binding
0.34	GO:0005515	protein binding
0.33	GO:0004386	helicase activity

0.50	GO:0048476	Holliday junction resolvase complex
0.40	GO:0005634	nucleus
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0043232	intracellular non-membrane-bounded organelle
0.34	GO:0044446	intracellular organelle part

0.64

GO:0004518

tr|T1FR90|T1FR90_HELRO
Uncharacterized protein
Search

tr|T1FR91|T1FR91_HELRO
Uncharacterized protein
Search

tr|T1FR92|T1FR92_HELRO
Uncharacterized protein
Search

0.45	GO:0005975	carbohydrate metabolic process
0.44	GO:2000026	regulation of multicellular organismal development
0.44	GO:0008101	decapentaplegic signaling pathway
0.44	GO:0036335	intestinal stem cell homeostasis
0.43	GO:0009996	negative regulation of cell fate specification
0.43	GO:0046843	dorsal appendage formation
0.43	GO:0016319	mushroom body development
0.43	GO:2000648	positive regulation of stem cell proliferation
0.43	GO:2000179	positive regulation of neural precursor cell proliferation
0.43	GO:0018990	ecdysis, chitin-based cuticle

0.48	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.47	GO:0030248	cellulose binding
0.42	GO:0008270	zinc ion binding
0.42	GO:0004887	thyroid hormone receptor activity
0.41	GO:0003707	steroid hormone receptor activity
0.40	GO:0004725	protein tyrosine phosphatase activity
0.40	GO:0003924	GTPase activity
0.39	GO:0004842	ubiquitin-protein transferase activity
0.39	GO:0005525	GTP binding
0.38	GO:0003676	nucleic acid binding

0.49	GO:0031362	anchored component of external side of plasma membrane
0.43	GO:0005783	endoplasmic reticulum
0.37	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.48	EC:3.2.1	GO:0004553
0.39	KEGG:R03876	GO:0004842

tr|T1FR93|T1FR93_HELRO
Uncharacterized protein
Search

0.38	GO:1903506	regulation of nucleic acid-templated transcription
0.38	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.38	GO:0010468	regulation of gene expression
0.36	GO:0016573	histone acetylation

0.51	GO:0003676	nucleic acid binding
0.39	GO:0046872	metal ion binding
0.36	GO:0004402	histone acetyltransferase activity

0.35	GO:0005622	intracellular
0.35	GO:0043227	membrane-bounded organelle

0.36

GO:0004402

tr|T1FR94|T1FR94_HELRO
Uncharacterized protein
Search

tr|T1FR95|T1FR95_HELRO
Uncharacterized protein
Search

tr|T1FR96|T1FR96_HELRO
Uncharacterized protein
Search

tr|T1FR97|T1FR97_HELRO
Uncharacterized protein
Search

0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.41	GO:0008345	larval locomotory behavior
0.40	GO:0002209	behavioral defense response
0.40	GO:0008344	adult locomotory behavior
0.39	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.34	GO:0001992	regulation of systemic arterial blood pressure by vasopressin

0.71	GO:0004930	G-protein coupled receptor activity
0.49	GO:0001653	peptide receptor activity

0.37

GO:0005887

integral component of plasma membrane

tr|T1FR98|T1FR98_HELRO
Uncharacterized protein
Search

tr|T1FR99|T1FR99_HELRO
Uncharacterized protein
Search

0.47

GO:0003676

nucleic acid binding

0.30

GO:0044425

membrane part

tr|T1FRA0|T1FRA0_HELRO
Uncharacterized protein
Search

tr|T1FRA1|T1FRA1_HELRO
Uncharacterized protein
Search

0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.41	GO:0008345	larval locomotory behavior
0.41	GO:0002209	behavioral defense response
0.40	GO:0008344	adult locomotory behavior
0.40	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.35	GO:0001992	regulation of systemic arterial blood pressure by vasopressin
0.33	GO:1902476	chloride transmembrane transport

0.71	GO:0004930	G-protein coupled receptor activity
0.50	GO:0001653	peptide receptor activity
0.34	GO:0015377	cation:chloride symporter activity

0.37

GO:0005887

integral component of plasma membrane

tr|T1FRA2|T1FRA2_HELRO
Uncharacterized protein
Search

tr|T1FRA3|T1FRA3_HELRO
Uncharacterized protein
Search

0.49	GO:0006275	regulation of DNA replication
0.47	GO:0045893	positive regulation of transcription, DNA-templated
0.44	GO:0006260	DNA replication
0.42	GO:0006996	organelle organization
0.41	GO:0060285	cilium-dependent cell motility
0.41	GO:0036211	protein modification process
0.41	GO:0071495	cellular response to endogenous stimulus
0.41	GO:0048207	vesicle targeting, rough ER to cis-Golgi
0.41	GO:0006461	protein complex assembly
0.41	GO:0071559	response to transforming growth factor beta

0.49	GO:0003688	DNA replication origin binding
0.41	GO:1901265	nucleoside phosphate binding
0.41	GO:0140096	catalytic activity, acting on a protein
0.41	GO:0097367	carbohydrate derivative binding
0.40	GO:0016301	kinase activity
0.40	GO:0036094	small molecule binding
0.40	GO:0043168	anion binding
0.40	GO:0008144	drug binding
0.40	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.40	GO:0046872	metal ion binding

0.45	GO:0042025	host cell nucleus
0.40	GO:0005814	centriole
0.39	GO:0005667	transcription factor complex
0.39	GO:0000139	Golgi membrane
0.38	GO:0005634	nucleus
0.38	GO:0005789	endoplasmic reticulum membrane
0.37	GO:0016459	myosin complex
0.36	GO:0005694	chromosome
0.30	GO:0016021	integral component of membrane

0.40

GO:0016773

tr|T1FRA4|T1FRA4_HELRO
Uncharacterized protein
Search

0.56	GO:0035556	intracellular signal transduction
0.42	GO:0046854	phosphatidylinositol phosphorylation
0.36	GO:0060963	positive regulation of ribosomal protein gene transcription by RNA polymerase II
0.36	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic
0.35	GO:0008361	regulation of cell size
0.35	GO:0035017	cuticle pattern formation
0.35	GO:0035222	wing disc pattern formation
0.35	GO:0001751	compound eye photoreceptor cell differentiation
0.35	GO:0016441	posttranscriptional gene silencing
0.35	GO:0008589	regulation of smoothened signaling pathway

0.43	GO:0016307	phosphatidylinositol phosphate kinase activity
0.41	GO:0005509	calcium ion binding
0.38	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0030306	ADP-ribosylation factor binding
0.36	GO:0016896	exoribonuclease activity, producing 5'-phosphomonoesters
0.35	GO:0008408	3'-5' exonuclease activity
0.35	GO:0000829	inositol heptakisphosphate kinase activity
0.35	GO:0005272	sodium channel activity

0.43	GO:0005622	intracellular
0.35	GO:0043227	membrane-bounded organelle
0.35	GO:1905354	exoribonuclease complex
0.34	GO:0048475	coated membrane
0.34	GO:0009986	cell surface
0.34	GO:0043233	organelle lumen
0.33	GO:0098796	membrane protein complex
0.33	GO:1990904	ribonucleoprotein complex
0.33	GO:0043228	non-membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.43

GO:0016307

tr|T1FRA5|T1FRA5_HELRO
Uncharacterized protein
Search

0.39	GO:0044267	cellular protein metabolic process
0.38	GO:0060255	regulation of macromolecule metabolic process
0.38	GO:0036211	protein modification process
0.38	GO:0050794	regulation of cellular process
0.38	GO:0031152	aggregation involved in sorocarp development
0.38	GO:0007064	mitotic sister chromatid cohesion
0.38	GO:0080090	regulation of primary metabolic process
0.38	GO:0051171	regulation of nitrogen compound metabolic process
0.38	GO:0009889	regulation of biosynthetic process
0.37	GO:0065009	regulation of molecular function

0.38	GO:0003743	translation initiation factor activity
0.38	GO:0005515	protein binding
0.38	GO:0004725	protein tyrosine phosphatase activity
0.38	GO:0098772	molecular function regulator
0.37	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.37	GO:0003727	single-stranded RNA binding
0.37	GO:0061630	ubiquitin protein ligase activity
0.37	GO:0004674	protein serine/threonine kinase activity
0.36	GO:0004526	ribonuclease P activity
0.35	GO:0003690	double-stranded DNA binding

0.39	GO:0000123	histone acetyltransferase complex
0.37	GO:0005669	transcription factor TFIID complex
0.36	GO:0005576	extracellular region
0.36	GO:0005938	cell cortex
0.36	GO:1905368	peptidase complex
0.30	GO:0016020	membrane

0.38

GO:0004725

tr|T1FRA6|T1FRA6_HELRO
Uncharacterized protein
Search

0.64

GO:0007018

microtubule-based movement

0.65	GO:0003777	microtubule motor activity
0.65	GO:0008017	microtubule binding
0.64	GO:0003779	actin binding
0.61	GO:0032403	protein complex binding
0.49	GO:0030554	adenyl nucleotide binding
0.49	GO:0032555	purine ribonucleotide binding
0.49	GO:0008144	drug binding
0.49	GO:0035639	purine ribonucleoside triphosphate binding

0.69	GO:0005856	cytoskeleton
0.53	GO:0043234	protein complex
0.51	GO:0044446	intracellular organelle part

tr|T1FRA7|T1FRA7_HELRO
Uncharacterized protein
Search

tr|T1FRA8|T1FRA8_HELRO
Uncharacterized protein
Search

tr|T1FRA9|T1FRA9_HELRO
Uncharacterized protein
Search

tr|T1FRB0|T1FRB0_HELRO
Uncharacterized protein
Search

tr|T1FRB1|T1FRB1_HELRO
Uncharacterized protein
Search

tr|T1FRB2|T1FRB2_HELRO
Uncharacterized protein
Search

0.85	Rna binding protein hnrnp m

0.59

GO:0003723

RNA binding

tr|T1FRB3|T1FRB3_HELRO
Uncharacterized protein
Search

0.48	GO:0017145	stem cell division
0.46	GO:0007281	germ cell development
0.46	GO:0008284	positive regulation of cell proliferation
0.38	GO:1903608	protein localization to cytoplasmic stress granule
0.38	GO:0042036	negative regulation of cytokine biosynthetic process
0.37	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.37	GO:0048024	regulation of mRNA splicing, via spliceosome
0.37	GO:0034249	negative regulation of cellular amide metabolic process
0.36	GO:0010629	negative regulation of gene expression
0.36	GO:2001141	regulation of RNA biosynthetic process

0.54	GO:0003723	RNA binding
0.47	GO:0003677	DNA binding
0.37	GO:0003700	DNA binding transcription factor activity
0.36	GO:0017076	purine nucleotide binding
0.36	GO:0097367	carbohydrate derivative binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0008144	drug binding
0.36	GO:0017111	nucleoside-triphosphatase activity
0.35	GO:0004672	protein kinase activity
0.34	GO:0005515	protein binding

0.47	GO:0010494	cytoplasmic stress granule
0.43	GO:0005634	nucleus
0.37	GO:0070013	intracellular organelle lumen
0.36	GO:0005829	cytosol
0.36	GO:0044446	intracellular organelle part
0.34	GO:0070062	extracellular exosome
0.34	GO:0005694	chromosome
0.34	GO:0032300	mismatch repair complex
0.34	GO:0031248	protein acetyltransferase complex
0.33	GO:0033202	DNA helicase complex

0.36

EC:3.6.1.15

GO:0017111

tr|T1FRB4|T1FRB4_HELRO
Uncharacterized protein
Search

tr|T1FRB5|T1FRB5_HELRO
Uncharacterized protein
Search

DDX56

0.63	DEAD-box helicase 56

0.53	GO:0010501	RNA secondary structure unwinding
0.47	GO:0006364	rRNA processing
0.43	GO:0010976	positive regulation of neuron projection development

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0003676	nucleic acid binding
0.51	GO:0004004	ATP-dependent RNA helicase activity

0.62	GO:0005730	nucleolus
0.38	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|T1FRB6|T1FRB6_HELRO
Uncharacterized protein
Search

0.46	GO:0000122	negative regulation of transcription by RNA polymerase II
0.45	GO:0045944	positive regulation of transcription by RNA polymerase II
0.35	GO:0006417	regulation of translation
0.34	GO:0006351	transcription, DNA-templated

0.48	GO:0046872	metal ion binding
0.39	GO:0016874	ligase activity
0.34	GO:0005515	protein binding
0.34	GO:0003723	RNA binding
0.33	GO:0016740	transferase activity

0.56	GO:0031981	nuclear lumen
0.53	GO:0005700	polytene chromosome
0.30	GO:0016020	membrane

0.39

GO:0016874

tr|T1FRB7|T1FRB7_HELRO
Uncharacterized protein
Search

tr|T1FRB8|T1FRB8_HELRO
Uncharacterized protein
Search

tr|T1FRB9|T1FRB9_HELRO
Uncharacterized protein
Search

0.49	Heterogeneous nuclear ribonucleoprotein K

0.61	GO:0006357	regulation of transcription by RNA polymerase II
0.55	GO:0006396	RNA processing
0.47	GO:0048024	regulation of mRNA splicing, via spliceosome
0.46	GO:1902165	regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
0.45	GO:0033119	negative regulation of RNA splicing
0.45	GO:0045716	positive regulation of low-density lipoprotein particle receptor biosynthetic process
0.44	GO:0010988	regulation of low-density lipoprotein particle clearance
0.43	GO:0048260	positive regulation of receptor-mediated endocytosis
0.42	GO:0032368	regulation of lipid transport
0.42	GO:0050686	negative regulation of mRNA processing

0.58	GO:0003723	RNA binding
0.49	GO:0003677	DNA binding
0.42	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.42	GO:0045296	cadherin binding
0.41	GO:0019904	protein domain specific binding
0.40	GO:0001067	regulatory region nucleic acid binding
0.40	GO:0042802	identical protein binding
0.39	GO:0008134	transcription factor binding
0.34	GO:0005521	lamin binding
0.34	GO:0008092	cytoskeletal protein binding

0.52	GO:0019013	viral nucleocapsid
0.50	GO:0035062	omega speckle
0.48	GO:0030529	intracellular ribonucleoprotein complex
0.47	GO:0000785	chromatin
0.41	GO:0044454	nuclear chromosome part
0.37	GO:0002102	podosome
0.37	GO:1902494	catalytic complex
0.36	GO:0030054	cell junction
0.35	GO:0031012	extracellular matrix
0.35	GO:0042995	cell projection

0.33

EC:1.2.1.27

GO:0004491

tr|T1FRC0|T1FRC0_HELRO
Uncharacterized protein
Search

tr|T1FRC1|T1FRC1_HELRO
Uncharacterized protein
Search

SUMF2

0.48	Sulfatase-modifying factor

0.46

GO:0055114

oxidation-reduction process

0.61	GO:0042803	protein homodimerization activity
0.47	GO:0016491	oxidoreductase activity

0.58	GO:0005783	endoplasmic reticulum
0.30	GO:0031224	intrinsic component of membrane

0.47

GO:0016491

tr|T1FRC2|T1FRC2_HELRO
Uncharacterized protein
Search

tr|T1FRC3|T1FRC3_HELRO
Uncharacterized protein
Search

tr|T1FRC4|T1FRC4_HELRO
Uncharacterized protein
Search

tr|T1FRC5|T1FRC5_HELRO
Uncharacterized protein
Search

0.52	WD repeat-containing protein 82

0.53	GO:0051568	histone H3-K4 methylation
0.50	GO:0018023	peptidyl-lysine trimethylation
0.38	GO:0030837	negative regulation of actin filament polymerization
0.33	GO:0016192	vesicle-mediated transport
0.33	GO:0006418	tRNA aminoacylation for protein translation
0.33	GO:0006468	protein phosphorylation

0.50	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.47	GO:0003682	chromatin binding
0.40	GO:0003779	actin binding
0.35	GO:0016905	myosin heavy chain kinase activity
0.33	GO:0003924	GTPase activity
0.33	GO:0016875	ligase activity, forming carbon-oxygen bonds
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.33	GO:0140101	catalytic activity, acting on a tRNA
0.33	GO:0032555	purine ribonucleotide binding

0.84	GO:0072357	PTW/PP1 phosphatase complex
0.80	GO:0048188	Set1C/COMPASS complex
0.46	GO:0000784	nuclear chromosome, telomeric region
0.44	GO:0005730	nucleolus
0.43	GO:0000785	chromatin
0.34	GO:0005802	trans-Golgi network
0.34	GO:0031982	vesicle
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:2.7.11.7

GO:0016905

tr|T1FRC6|T1FRC6_HELRO
Uncharacterized protein
Search

0.38	Cytoplasmic aconitate hydratase

0.81	GO:0010040	response to iron(II) ion
0.70	GO:0006879	cellular iron ion homeostasis
0.42	GO:0007370	ventral furrow formation
0.30	GO:0008152	metabolic process

0.75	GO:0003994	aconitate hydratase activity
0.66	GO:0051539	4 iron, 4 sulfur cluster binding
0.45	GO:0030350	iron-responsive element binding

0.47	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.75

EC:4.2.1.3

GO:0003994

tr|T1FRC7|T1FRC7_HELRO
Uncharacterized protein
Search

0.10	Transportin-3

0.50	GO:0006886	intracellular protein transport
0.41	GO:0006606	protein import into nucleus
0.36	GO:0016567	protein ubiquitination
0.34	GO:0016310	phosphorylation
0.34	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity
0.33	GO:0006289	nucleotide-excision repair

0.55	GO:0008536	Ran GTPase binding
0.42	GO:0008139	nuclear localization sequence binding
0.39	GO:0008565	protein transporter activity
0.36	GO:0004842	ubiquitin-protein transferase activity
0.34	GO:0016301	kinase activity
0.34	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity

0.61	GO:0005634	nucleus
0.38	GO:0012505	endomembrane system
0.37	GO:0031967	organelle envelope
0.37	GO:0031090	organelle membrane
0.34	GO:0005737	cytoplasm
0.33	GO:1902554	serine/threonine protein kinase complex
0.33	GO:0000428	DNA-directed RNA polymerase complex
0.33	GO:0005667	transcription factor complex
0.33	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

0.36

GO:0004842

tr|T1FRC8|T1FRC8_HELRO
Uncharacterized protein
Search

0.44	GO:0009996	negative regulation of cell fate specification
0.40	GO:0006325	chromatin organization
0.39	GO:0018205	peptidyl-lysine modification
0.39	GO:0055088	lipid homeostasis
0.38	GO:0006479	protein methylation
0.38	GO:0070896	positive regulation of transposon integration
0.37	GO:0006886	intracellular protein transport
0.37	GO:0016348	imaginal disc-derived leg joint morphogenesis
0.37	GO:0018992	germ-line sex determination
0.37	GO:0035017	cuticle pattern formation

0.49	GO:0032559	adenyl ribonucleotide binding
0.49	GO:0008144	drug binding
0.49	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0004386	helicase activity
0.40	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.39	GO:0017137	Rab GTPase binding
0.38	GO:0003676	nucleic acid binding
0.37	GO:0046872	metal ion binding
0.36	GO:0004402	histone acetyltransferase activity
0.36	GO:0003713	transcription coactivator activity

0.40	GO:0005634	nucleus
0.38	GO:0034708	methyltransferase complex
0.37	GO:0044446	intracellular organelle part
0.37	GO:0031974	membrane-enclosed lumen
0.36	GO:0012505	endomembrane system
0.35	GO:0031090	organelle membrane
0.35	GO:0031975	envelope
0.30	GO:0016021	integral component of membrane

0.36

GO:0004402

tr|T1FRC9|T1FRC9_HELRO
Uncharacterized protein
Search

MPPE1

0.43	Metallophosphoesterase

0.77	GO:0006888	ER to Golgi vesicle-mediated transport
0.44	GO:0006506	GPI anchor biosynthetic process
0.41	GO:0006044	N-acetylglucosamine metabolic process
0.40	GO:0051301	cell division
0.39	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.37	GO:0005975	carbohydrate metabolic process
0.34	GO:0071805	potassium ion transmembrane transport
0.32	GO:0006468	protein phosphorylation

0.51	GO:0016787	hydrolase activity
0.41	GO:0034235	GPI anchor binding
0.40	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses
0.38	GO:0030145	manganese ion binding
0.35	GO:0016286	small conductance calcium-activated potassium channel activity
0.34	GO:0005516	calmodulin binding
0.32	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0008144	drug binding

0.48	GO:0005737	cytoplasm
0.45	GO:0012505	endomembrane system
0.43	GO:0005654	nucleoplasm
0.40	GO:0005801	cis-Golgi network
0.38	GO:0098588	bounding membrane of organelle
0.34	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane

0.51

GO:0016787

tr|T1FRD0|T1FRD0_HELRO
Uncharacterized protein
Search

tr|T1FRD1|T1FRD1_HELRO
Uncharacterized protein
Search

0.10	calcium-binding acidic-repeat protein-like

0.51	GO:0007155	cell adhesion
0.44	GO:0030198	extracellular matrix organization
0.39	GO:0006457	protein folding
0.38	GO:0006950	response to stress
0.35	GO:0036211	protein modification process
0.34	GO:0044267	cellular protein metabolic process
0.34	GO:0046776	suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I
0.33	GO:0016310	phosphorylation
0.32	GO:0006508	proteolysis

0.68	GO:0005509	calcium ion binding
0.40	GO:0051082	unfolded protein binding
0.36	GO:0032555	purine ribonucleotide binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0030554	adenyl nucleotide binding
0.36	GO:0008144	drug binding
0.35	GO:0004674	protein serine/threonine kinase activity
0.34	GO:0042288	MHC class I protein binding
0.34	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.34	GO:0032550	purine ribonucleoside binding

0.43	GO:0030312	external encapsulating structure
0.42	GO:0019867	outer membrane
0.42	GO:0030313	cell envelope
0.42	GO:0031012	extracellular matrix
0.34	GO:0044165	host cell endoplasmic reticulum
0.30	GO:0016021	integral component of membrane

0.35

GO:0004674

tr|T1FRD2|T1FRD2_HELRO
Uncharacterized protein
Search

0.52	GO:0030433	ubiquitin-dependent ERAD pathway
0.39	GO:0005975	carbohydrate metabolic process
0.38	GO:0006986	response to unfolded protein
0.37	GO:0036211	protein modification process
0.37	GO:0006397	mRNA processing
0.35	GO:0016310	phosphorylation

0.41	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.37	GO:0016805	dipeptidase activity
0.37	GO:0030246	carbohydrate binding
0.36	GO:0016757	transferase activity, transferring glycosyl groups
0.36	GO:0004672	protein kinase activity
0.35	GO:0003676	nucleic acid binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.47	GO:0005783	endoplasmic reticulum
0.46	GO:0005829	cytosol
0.39	GO:0005576	extracellular region
0.37	GO:0005635	nuclear envelope
0.37	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.41

GO:0004553

tr|T1FRD3|T1FRD3_HELRO
Uncharacterized protein
Search

0.25	Chromatin target of PRMT1 protein

tr|T1FRD4|T1FRD4_HELRO
Uncharacterized protein
Search

0.47	GO:0034368	protein-lipid complex remodeling
0.45	GO:0006621	protein retention in ER lumen
0.45	GO:0030433	ubiquitin-dependent ERAD pathway
0.44	GO:0016050	vesicle organization
0.44	GO:0006505	GPI anchor metabolic process
0.44	GO:0006888	ER to Golgi vesicle-mediated transport
0.37	GO:0015031	protein transport

0.61	GO:0016788	hydrolase activity, acting on ester bonds
0.33	GO:0008374	O-acyltransferase activity

0.43	GO:0005783	endoplasmic reticulum
0.38	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.37	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.61

GO:0016788

tr|T1FRD5|T1FRD5_HELRO
Uncharacterized protein
Search

0.67	Ran GTPase-activating protein 1

0.75	GO:0043547	positive regulation of GTPase activity
0.55	GO:0007165	signal transduction
0.35	GO:0051641	cellular localization
0.33	GO:0051234	establishment of localization
0.32	GO:0046825	regulation of protein export from nucleus
0.32	GO:0046823	negative regulation of nucleocytoplasmic transport
0.32	GO:0051224	negative regulation of protein transport
0.32	GO:0045185	maintenance of protein location

0.76	GO:0005096	GTPase activator activity
0.33	GO:0046872	metal ion binding
0.32	GO:0045296	cadherin binding
0.32	GO:0008536	Ran GTPase binding
0.31	GO:0003723	RNA binding

0.36	GO:0000776	kinetochore
0.33	GO:0005737	cytoplasm
0.32	GO:0016235	aggresome
0.32	GO:0031965	nuclear membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1FRD6|T1FRD6_HELRO
Uncharacterized protein
Search

0.11	Sorting nexin-30 (Fragment)

0.42	GO:0016050	vesicle organization
0.40	GO:0016192	vesicle-mediated transport
0.40	GO:0098657	import into cell
0.35	GO:0001889	liver development
0.35	GO:0016482	cytosolic transport
0.35	GO:0016197	endosomal transport
0.35	GO:0043066	negative regulation of apoptotic process
0.35	GO:0006915	apoptotic process
0.34	GO:0015031	protein transport
0.34	GO:0034727	piecemeal microautophagy of the nucleus

0.77	GO:0035091	phosphatidylinositol binding
0.36	GO:0097153	cysteine-type endopeptidase activity involved in apoptotic process
0.32	GO:0003779	actin binding
0.32	GO:0004672	protein kinase activity
0.32	GO:0005524	ATP binding

0.42	GO:0005768	endosome
0.42	GO:0019898	extrinsic component of membrane
0.34	GO:0005829	cytosol
0.34	GO:0000407	phagophore assembly site
0.30	GO:0016021	integral component of membrane

tr|T1FRD7|T1FRD7_HELRO
Clathrin heavy chain
Search

0.40	Clathrin heavy chain

0.83	GO:0048268	clathrin coat assembly
0.69	GO:0006886	intracellular protein transport
0.69	GO:0016192	vesicle-mediated transport
0.40	GO:0022609	multicellular organism adhesion to substrate
0.40	GO:0046667	compound eye retinal cell programmed cell death
0.39	GO:2000366	positive regulation of STAT protein import into nucleus
0.39	GO:0035002	liquid clearance, open tracheal system
0.39	GO:0008103	oocyte microtubule cytoskeleton polarization
0.39	GO:0045451	pole plasm oskar mRNA localization
0.39	GO:0035159	regulation of tube length, open tracheal system

0.85	GO:0032051	clathrin light chain binding
0.61	GO:0005198	structural molecule activity
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.85	GO:0071439	clathrin complex
0.81	GO:0030130	clathrin coat of trans-Golgi network vesicle
0.80	GO:0030132	clathrin coat of coated pit
0.41	GO:0019028	viral capsid
0.38	GO:0030141	secretory granule
0.37	GO:0005802	trans-Golgi network
0.37	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0098793	presynapse
0.37	GO:0005938	cell cortex

tr|T1FRD8|T1FRD8_HELRO
Uncharacterized protein
Search

0.41	GO:0016188	synaptic vesicle maturation
0.41	GO:0016082	synaptic vesicle priming
0.41	GO:0035249	synaptic transmission, glutamatergic
0.41	GO:0035023	regulation of Rho protein signal transduction
0.40	GO:0065009	regulation of molecular function
0.40	GO:0048268	clathrin coat assembly
0.39	GO:0035556	intracellular signal transduction
0.39	GO:0007059	chromosome segregation
0.38	GO:0051301	cell division
0.38	GO:0036211	protein modification process

0.52	GO:0045735	nutrient reservoir activity
0.44	GO:0005515	protein binding
0.43	GO:0005509	calcium ion binding
0.42	GO:0005543	phospholipid binding
0.41	GO:0098772	molecular function regulator
0.40	GO:0019992	diacylglycerol binding
0.39	GO:0003677	DNA binding
0.38	GO:0004674	protein serine/threonine kinase activity
0.38	GO:0030554	adenyl nucleotide binding
0.37	GO:0097367	carbohydrate derivative binding

0.39	GO:0030136	clathrin-coated vesicle
0.39	GO:0098793	presynapse
0.38	GO:0005634	nucleus
0.37	GO:0044430	cytoskeletal part
0.37	GO:0099512	supramolecular fiber
0.37	GO:0005927	muscle tendon junction
0.36	GO:0005915	zonula adherens
0.36	GO:0045178	basal part of cell
0.36	GO:0071944	cell periphery
0.36	GO:0015629	actin cytoskeleton

0.38

GO:0004674

tr|T1FRD9|T1FRD9_HELRO
Uncharacterized protein
Search

0.78	Heterogeneous nuclear ribonucleoprotein H

0.43	GO:0030855	epithelial cell differentiation
0.41	GO:0007311	maternal specification of dorsal/ventral axis, oocyte, germ-line encoded
0.40	GO:0045451	pole plasm oskar mRNA localization
0.39	GO:0046427	positive regulation of JAK-STAT cascade
0.38	GO:0042060	wound healing
0.37	GO:0006417	regulation of translation
0.36	GO:0051276	chromosome organization
0.34	GO:0000398	mRNA splicing, via spliceosome

0.59	GO:0003723	RNA binding
0.34	GO:0005515	protein binding

0.60	GO:0019013	viral nucleocapsid
0.53	GO:0030529	intracellular ribonucleoprotein complex
0.43	GO:0005654	nucleoplasm
0.36	GO:0005829	cytosol
0.35	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

tr|T1FRE0|T1FRE0_HELRO
Uncharacterized protein
Search

0.40	Fanconi anemia group J protein

0.70	GO:0032392	DNA geometric change
0.49	GO:0046483	heterocycle metabolic process
0.49	GO:1901360	organic cyclic compound metabolic process
0.49	GO:0006725	cellular aromatic compound metabolic process
0.45	GO:0006807	nitrogen compound metabolic process
0.30	GO:0044238	primary metabolic process

0.72	GO:0004003	ATP-dependent DNA helicase activity
0.55	GO:0030554	adenyl nucleotide binding
0.55	GO:0003677	DNA binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.60

GO:0005634

nucleus

tr|T1FRE1|T1FRE1_HELRO
Uncharacterized protein
Search

tr|T1FRE2|T1FRE2_HELRO
Uncharacterized protein
Search

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.39	GO:0008101	decapentaplegic signaling pathway
0.39	GO:0036335	intestinal stem cell homeostasis
0.39	GO:0009996	negative regulation of cell fate specification
0.39	GO:0046843	dorsal appendage formation
0.39	GO:0002052	positive regulation of neuroblast proliferation
0.39	GO:0016319	mushroom body development
0.39	GO:0001751	compound eye photoreceptor cell differentiation

0.61	GO:0003700	DNA binding transcription factor activity
0.35	GO:0017095	heparan sulfate 6-O-sulfotransferase activity

0.35	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.35

EC:2.8.2

GO:0017095

tr|T1FRE3|T1FRE3_HELRO
Uncharacterized protein
Search

0.54	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.42	GO:1903041	regulation of chondrocyte hypertrophy
0.41	GO:0021954	central nervous system neuron development
0.40	GO:0051256	mitotic spindle midzone assembly
0.38	GO:0007088	regulation of mitotic nuclear division
0.37	GO:0060548	negative regulation of cell death
0.37	GO:1903288	positive regulation of potassium ion import
0.36	GO:0090263	positive regulation of canonical Wnt signaling pathway

0.57	GO:0003723	RNA binding
0.51	GO:0046872	metal ion binding
0.38	GO:0003682	chromatin binding
0.37	GO:0005544	calcium-dependent phospholipid binding
0.36	GO:0005515	protein binding
0.35	GO:0045735	nutrient reservoir activity
0.35	GO:0004386	helicase activity
0.35	GO:0008146	sulfotransferase activity
0.34	GO:0004674	protein serine/threonine kinase activity
0.34	GO:0032559	adenyl ribonucleotide binding

0.47	GO:0031981	nuclear lumen
0.38	GO:0005737	cytoplasm
0.35	GO:0043232	intracellular non-membrane-bounded organelle
0.33	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.35

EC:2.8.2

GO:0008146

tr|T1FRE4|T1FRE4_HELRO
Uncharacterized protein
Search

tr|T1FRE5|T1FRE5_HELRO
Uncharacterized protein
Search

tr|T1FRE6|T1FRE6_HELRO
Uncharacterized protein
Search

0.51	GO:0007411	axon guidance
0.50	GO:0019226	transmission of nerve impulse
0.50	GO:0042552	myelination
0.50	GO:0007422	peripheral nervous system development
0.49	GO:0050808	synapse organization
0.44	GO:0035023	regulation of Rho protein signal transduction
0.42	GO:0006468	protein phosphorylation
0.41	GO:0065009	regulation of molecular function
0.40	GO:0007155	cell adhesion
0.40	GO:0021828	gonadotrophin-releasing hormone neuronal migration to the hypothalamus

0.44	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.42	GO:0004672	protein kinase activity
0.41	GO:0005509	calcium ion binding
0.39	GO:0005042	netrin receptor activity
0.39	GO:0032559	adenyl ribonucleotide binding
0.38	GO:0008144	drug binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0016787	hydrolase activity
0.34	GO:0003676	nucleic acid binding

0.35

GO:0005887

integral component of plasma membrane

0.34

GO:0016787

tr|T1FRE7|T1FRE7_HELRO
Uncharacterized protein
Search

tr|T1FRE8|T1FRE8_HELRO
Uncharacterized protein
Search

tr|T1FRE9|T1FRE9_HELRO
Uncharacterized protein
Search

tr|T1FRF0|T1FRF0_HELRO
Uncharacterized protein
Search

tr|T1FRF1|T1FRF1_HELRO
Uncharacterized protein
Search

tr|T1FRF2|T1FRF2_HELRO
Uncharacterized protein
Search

tr|T1FRF3|T1FRF3_HELRO
Uncharacterized protein
Search

0.51	TIMELESS-interacting protein

0.85	GO:0048478	replication fork protection
0.67	GO:0007049	cell cycle
0.65	GO:0006974	cellular response to DNA damage stimulus
0.46	GO:0000076	DNA replication checkpoint
0.44	GO:0008284	positive regulation of cell proliferation
0.44	GO:0045930	negative regulation of mitotic cell cycle
0.42	GO:0043111	replication fork arrest
0.41	GO:0033262	regulation of nuclear cell cycle DNA replication
0.41	GO:0009411	response to UV
0.36	GO:0071515	genetic imprinting at mating-type locus

0.35	GO:0031072	heat shock protein binding
0.35	GO:0003677	DNA binding
0.35	GO:0051082	unfolded protein binding
0.33	GO:0046872	metal ion binding

0.61	GO:0005634	nucleus
0.42	GO:0000785	chromatin
0.41	GO:0031974	membrane-enclosed lumen
0.39	GO:0005657	replication fork
0.36	GO:0043234	protein complex
0.35	GO:0005737	cytoplasm

tr|T1FRF4|T1FRF4_HELRO
Uncharacterized protein
Search

0.42	Putative serine/threonine protein phosphatase

0.72	GO:0006470	protein dephosphorylation
0.44	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
0.44	GO:0000165	MAPK cascade
0.33	GO:0007264	small GTPase mediated signal transduction
0.33	GO:0000398	mRNA splicing, via spliceosome
0.33	GO:0065009	regulation of molecular function

0.77	GO:0004722	protein serine/threonine phosphatase activity
0.51	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding
0.33	GO:0098772	molecular function regulator
0.32	GO:0003676	nucleic acid binding

0.35	GO:0005622	intracellular
0.34	GO:0070062	extracellular exosome
0.32	GO:0043234	protein complex
0.32	GO:0044422	organelle part
0.30	GO:0016020	membrane

tr|T1FRF5|T1FRF5_HELRO
Uncharacterized protein
Search

tr|T1FRF6|T1FRF6_HELRO
Uncharacterized protein
Search

tr|T1FRF7|T1FRF7_HELRO
Uncharacterized protein
Search

0.53	GO:0007165	signal transduction
0.49	GO:0045879	negative regulation of smoothened signaling pathway
0.46	GO:0055034	Bolwig's organ development
0.46	GO:0045165	cell fate commitment
0.46	GO:0035107	appendage morphogenesis
0.46	GO:2000274	regulation of epithelial cell migration, open tracheal system
0.46	GO:0060562	epithelial tube morphogenesis
0.45	GO:0007411	axon guidance
0.45	GO:0035215	genital disc development
0.45	GO:0009887	animal organ morphogenesis

0.75	GO:0008158	hedgehog receptor activity
0.45	GO:0030228	lipoprotein particle receptor activity
0.43	GO:0005119	smoothened binding
0.43	GO:0097108	hedgehog family protein binding
0.41	GO:0005113	patched binding
0.40	GO:0015485	cholesterol binding
0.40	GO:0008201	heparin binding
0.40	GO:0030332	cyclin binding
0.38	GO:0032403	protein complex binding
0.34	GO:0004149	dihydrolipoyllysine-residue succinyltransferase activity

0.46	GO:0048471	perinuclear region of cytoplasm
0.45	GO:0045169	fusome
0.45	GO:0005929	cilium
0.44	GO:0030139	endocytic vesicle
0.40	GO:0044459	plasma membrane part
0.40	GO:0030496	midbody
0.39	GO:0098857	membrane microdomain
0.39	GO:0044294	dendritic growth cone
0.38	GO:0044295	axonal growth cone
0.38	GO:0005794	Golgi apparatus

0.34	EC:2.3.1.61	GO:0004149
0.34	KEGG:R03876	GO:0004842

tr|T1FRF8|T1FRF8_HELRO
Uncharacterized protein
Search

tr|T1FRF9|T1FRF9_HELRO
Uncharacterized protein
Search

0.61	GO:0006468	protein phosphorylation
0.45	GO:0007018	microtubule-based movement
0.39	GO:0000916	actomyosin contractile ring contraction
0.39	GO:0000920	cell separation after cytokinesis
0.39	GO:0044837	actomyosin contractile ring organization
0.39	GO:0000912	assembly of actomyosin apparatus involved in cytokinesis

0.67	GO:0004674	protein serine/threonine kinase activity
0.48	GO:0032559	adenyl ribonucleotide binding
0.47	GO:0008144	drug binding
0.47	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0051015	actin filament binding
0.45	GO:0003777	microtubule motor activity
0.45	GO:0008017	microtubule binding
0.37	GO:0000146	microfilament motor activity

0.46	GO:0016459	myosin complex
0.40	GO:0000142	cellular bud neck contractile ring
0.39	GO:0000131	incipient cellular bud site
0.30	GO:0016020	membrane

0.67

GO:0004674

tr|T1FRG0|T1FRG0_HELRO
Uncharacterized protein
Search

0.41	GO:0036211	protein modification process
0.40	GO:0006325	chromatin organization
0.40	GO:0044267	cellular protein metabolic process
0.39	GO:0065007	biological regulation
0.39	GO:0031154	culmination involved in sorocarp development
0.39	GO:0006796	phosphate-containing compound metabolic process
0.39	GO:0051179	localization
0.38	GO:0051716	cellular response to stimulus
0.38	GO:0031038	myosin II filament organization
0.37	GO:0022406	membrane docking

0.42	GO:0003676	nucleic acid binding
0.41	GO:0140096	catalytic activity, acting on a protein
0.40	GO:0017076	purine nucleotide binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0032553	ribonucleotide binding
0.40	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.40	GO:0046872	metal ion binding
0.39	GO:0016301	kinase activity
0.39	GO:0003924	GTPase activity
0.39	GO:0001883	purine nucleoside binding

0.44	GO:0005634	nucleus
0.39	GO:0070013	intracellular organelle lumen
0.38	GO:1902494	catalytic complex
0.38	GO:0044446	intracellular organelle part
0.38	GO:0043232	intracellular non-membrane-bounded organelle
0.37	GO:0032300	mismatch repair complex
0.37	GO:0070938	contractile ring
0.36	GO:0032155	cell division site part
0.36	GO:0005615	extracellular space
0.36	GO:0044448	cell cortex part

0.40

GO:0016773

tr|T1FRG1|T1FRG1_HELRO
Uncharacterized protein
Search

LOC106156405

0.76	Cys-loop ligand-gated ionic channel

0.60	GO:0007165	signal transduction
0.60	GO:0034220	ion transmembrane transport
0.35	GO:0015074	DNA integration
0.35	GO:0006821	chloride transport
0.35	GO:0006486	protein glycosylation
0.35	GO:0006310	DNA recombination
0.34	GO:0006334	nucleosome assembly

0.75	GO:0005230	extracellular ligand-gated ion channel activity
0.69	GO:0004888	transmembrane signaling receptor activity
0.35	GO:0008378	galactosyltransferase activity
0.35	GO:0004075	biotin carboxylase activity
0.35	GO:0005254	chloride channel activity
0.34	GO:0003677	DNA binding
0.34	GO:0042393	histone binding
0.34	GO:0046982	protein heterodimerization activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding

0.35	GO:0005794	Golgi apparatus
0.35	GO:0000788	nuclear nucleosome
0.30	GO:0016020	membrane

0.35

GO:0008378

tr|T1FRG2|T1FRG2_HELRO
Uncharacterized protein
Search

tr|T1FRG3|T1FRG3_HELRO
Uncharacterized protein
Search

tr|T1FRG4|T1FRG4_HELRO
Uncharacterized protein
Search

0.51	Orexin receptor type 2

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.54	GO:0007631	feeding behavior
0.48	GO:0043006	activation of phospholipase A2 activity by calcium-mediated signaling
0.47	GO:0007625	grooming behavior
0.47	GO:0002021	response to dietary excess
0.47	GO:0048265	response to pain
0.46	GO:0051480	regulation of cytosolic calcium ion concentration
0.46	GO:0035587	purinergic receptor signaling pathway
0.46	GO:0048016	inositol phosphate-mediated signaling
0.45	GO:0050482	arachidonic acid secretion

0.72	GO:0004930	G-protein coupled receptor activity
0.68	GO:0001653	peptide receptor activity
0.48	GO:0042924	neuromedin U binding
0.47	GO:0061778	intracellular chloride channel activity
0.46	GO:0035586	purinergic receptor activity
0.44	GO:0030594	neurotransmitter receptor activity
0.42	GO:0022839	ion gated channel activity
0.42	GO:0008381	mechanosensitive ion channel activity
0.40	GO:0005525	GTP binding
0.35	GO:0050254	rhodopsin kinase activity

0.42	GO:0005887	integral component of plasma membrane
0.35	GO:0005622	intracellular
0.34	GO:0012506	vesicle membrane
0.34	GO:0098805	whole membrane
0.34	GO:0098588	bounding membrane of organelle
0.34	GO:0012505	endomembrane system
0.34	GO:0098793	presynapse
0.33	GO:0048475	coated membrane
0.32	GO:0098796	membrane protein complex

0.35

EC:2.7.11.14

GO:0050254

tr|T1FRG5|T1FRG5_HELRO
Transporter
Search

SLC6A14

0.47	Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)

0.76	GO:0006836	neurotransmitter transport
0.55	GO:0055085	transmembrane transport
0.45	GO:0009636	response to toxic substance
0.38	GO:0006520	cellular amino acid metabolic process
0.36	GO:0006865	amino acid transport
0.35	GO:0015837	amine transport
0.35	GO:0060012	synaptic transmission, glycinergic
0.34	GO:0071450	cellular response to oxygen radical
0.34	GO:0000303	response to superoxide
0.34	GO:0006801	superoxide metabolic process

0.79	GO:0005328	neurotransmitter:sodium symporter activity
0.35	GO:0005283	sodium:amino acid symporter activity
0.34	GO:0004784	superoxide dismutase activity
0.34	GO:0015187	glycine transmembrane transporter activity
0.34	GO:0005275	amine transmembrane transporter activity
0.34	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity
0.34	GO:0015296	anion:cation symporter activity
0.32	GO:0046872	metal ion binding

0.42	GO:0005887	integral component of plasma membrane
0.39	GO:0031526	brush border membrane
0.35	GO:0070062	extracellular exosome

0.34

EC:1.15.1.1

GO:0004784

tr|T1FRG6|T1FRG6_HELRO
Uncharacterized protein
Search

tr|T1FRG7|T1FRG7_HELRO
Uncharacterized protein
Search

0.10	Twinkle protein, mitochondrial (Fragment)

0.70	GO:0032392	DNA geometric change
0.66	GO:0006260	DNA replication
0.55	GO:0032042	mitochondrial DNA metabolic process
0.54	GO:0034214	protein hexamerization
0.53	GO:0006390	mitochondrial transcription
0.50	GO:0051260	protein homooligomerization
0.39	GO:0071333	cellular response to glucose stimulus
0.34	GO:0046854	phosphatidylinositol phosphorylation
0.33	GO:0051301	cell division
0.33	GO:0009072	aromatic amino acid family metabolic process

0.71	GO:0003678	DNA helicase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0002020	protease binding
0.49	GO:0003697	single-stranded DNA binding
0.36	GO:0003690	double-stranded DNA binding
0.35	GO:0051537	2 iron, 2 sulfur cluster binding
0.33	GO:0003868	4-hydroxyphenylpyruvate dioxygenase activity
0.33	GO:0020037	heme binding

0.52	GO:0042645	mitochondrial nucleoid
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:1.13.11.27

GO:0003868

tr|T1FRG8|T1FRG8_HELRO
Uncharacterized protein
Search

tr|T1FRG9|T1FRG9_HELRO
Uncharacterized protein
Search

tr|T1FRH0|T1FRH0_HELRO
Uncharacterized protein
Search

tr|T1FRH1|T1FRH1_HELRO
Uncharacterized protein
Search

0.80	GO:0071526	semaphorin-plexin signaling pathway
0.51	GO:0021935	cerebellar granule cell precursor tangential migration
0.49	GO:0060174	limb bud formation
0.48	GO:0060037	pharyngeal system development
0.48	GO:0051642	centrosome localization
0.47	GO:0001756	somitogenesis
0.47	GO:0051270	regulation of cellular component movement
0.47	GO:0040012	regulation of locomotion
0.47	GO:0021915	neural tube development
0.47	GO:0021785	branchiomotor neuron axon guidance

0.80	GO:0017154	semaphorin receptor activity
0.44	GO:0042802	identical protein binding
0.37	GO:0016984	ribulose-bisphosphate carboxylase activity
0.36	GO:0000287	magnesium ion binding
0.34	GO:0016788	hydrolase activity, acting on ester bonds
0.34	GO:0003777	microtubule motor activity
0.33	GO:0000829	inositol heptakisphosphate kinase activity
0.33	GO:0046983	protein dimerization activity
0.33	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0016874	ligase activity

0.42	GO:0005887	integral component of plasma membrane
0.35	GO:0002116	semaphorin receptor complex
0.33	GO:0005634	nucleus
0.32	GO:0000785	chromatin
0.32	GO:0070013	intracellular organelle lumen
0.32	GO:1904949	ATPase complex
0.31	GO:0005737	cytoplasm

0.37	EC:4.1.1.39	GO:0016984
0.33	KEGG:R03876	GO:0004842

tr|T1FRH2|T1FRH2_HELRO
Uncharacterized protein
Search

tr|T1FRH3|T1FRH3_HELRO
Uncharacterized protein
Search

0.46	Mitogen-activated protein kinase kinase kinase

0.63	GO:0006468	protein phosphorylation
0.49	GO:0048082	regulation of adult chitin-containing cuticle pigmentation
0.47	GO:0043410	positive regulation of MAPK cascade
0.46	GO:0070304	positive regulation of stress-activated protein kinase signaling cascade
0.46	GO:0046328	regulation of JNK cascade
0.41	GO:0043405	regulation of MAP kinase activity
0.41	GO:0032147	activation of protein kinase activity
0.41	GO:0071902	positive regulation of protein serine/threonine kinase activity
0.37	GO:0018212	peptidyl-tyrosine modification
0.37	GO:0035556	intracellular signal transduction

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0005057	signal transducer activity, downstream of receptor
0.33	GO:0016428	tRNA (cytosine-5-)-methyltransferase activity
0.33	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.33	GO:0005509	calcium ion binding
0.32	GO:0003723	RNA binding
0.32	GO:0003755	peptidyl-prolyl cis-trans isomerase activity

0.37	GO:1902911	protein kinase complex
0.34	GO:0005622	intracellular
0.30	GO:0016020	membrane

0.33

GO:0016428

tr|T1FRH4|T1FRH4_HELRO
Uncharacterized protein
Search

0.75	Stromal interaction molecule 1a

0.66	GO:0065009	regulation of molecular function
0.59	GO:1904427	positive regulation of calcium ion transmembrane transport
0.48	GO:0002115	store-operated calcium entry
0.45	GO:0006874	cellular calcium ion homeostasis

0.85	GO:0005246	calcium channel regulator activity
0.42	GO:0005509	calcium ion binding

0.51	GO:0005783	endoplasmic reticulum
0.48	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.46	GO:0031984	organelle subcompartment
0.38	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1FRH5|T1FRH5_HELRO
Uncharacterized protein
Search

0.68

GO:0051726

regulation of cell cycle

0.45

GO:0005634

nucleus

tr|T1FRH6|T1FRH6_HELRO
Uncharacterized protein
Search

0.43	GO:0006468	protein phosphorylation
0.41	GO:0050829	defense response to Gram-negative bacterium
0.40	GO:0051641	cellular localization
0.39	GO:0032504	multicellular organism reproduction
0.39	GO:0060255	regulation of macromolecule metabolic process
0.38	GO:0080090	regulation of primary metabolic process
0.38	GO:0031323	regulation of cellular metabolic process
0.38	GO:0051171	regulation of nitrogen compound metabolic process
0.38	GO:0140029	exocytic process
0.37	GO:0022406	membrane docking

0.43	GO:0004672	protein kinase activity
0.40	GO:0032559	adenyl ribonucleotide binding
0.40	GO:0008144	drug binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0005509	calcium ion binding
0.39	GO:0003676	nucleic acid binding
0.39	GO:0003700	DNA binding transcription factor activity
0.38	GO:0005515	protein binding
0.37	GO:0008270	zinc ion binding
0.36	GO:0008047	enzyme activator activity

0.39	GO:0043231	intracellular membrane-bounded organelle
0.38	GO:0005615	extracellular space
0.38	GO:0012505	endomembrane system
0.37	GO:0005667	transcription factor complex
0.37	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0031362	anchored component of external side of plasma membrane
0.36	GO:0005938	cell cortex
0.35	GO:0030687	preribosome, large subunit precursor
0.35	GO:0097458	neuron part
0.34	GO:0000785	chromatin

0.36

GO:0004721

tr|T1FRH7|T1FRH7_HELRO
Uncharacterized protein
Search

tr|T1FRH8|T1FRH8_HELRO
Uncharacterized protein
Search

tr|T1FRH9|T1FRH9_HELRO
Uncharacterized protein
Search

tr|T1FRI0|T1FRI0_HELRO
Uncharacterized protein
Search

0.35	Calcium binding protein 39

0.71	GO:0001700	embryonic development via the syncytial blastoderm
0.66	GO:0010800	positive regulation of peptidyl-threonine phosphorylation
0.62	GO:0032147	activation of protein kinase activity
0.62	GO:0018105	peptidyl-serine phosphorylation
0.61	GO:0071902	positive regulation of protein serine/threonine kinase activity
0.52	GO:0023014	signal transduction by protein phosphorylation
0.50	GO:0035556	intracellular signal transduction
0.45	GO:0051291	protein heterooligomerization
0.39	GO:0006357	regulation of transcription by RNA polymerase II

0.64	GO:0043539	protein serine/threonine kinase activator activity
0.60	GO:0019900	kinase binding
0.56	GO:0004674	protein serine/threonine kinase activity
0.41	GO:0001104	RNA polymerase II transcription cofactor activity

0.54	GO:0005634	nucleus
0.44	GO:0005737	cytoplasm
0.40	GO:0043234	protein complex
0.39	GO:0070062	extracellular exosome
0.38	GO:0031974	membrane-enclosed lumen
0.36	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.56

GO:0004674

tr|T1FRI1|T1FRI1_HELRO
Uncharacterized protein
Search

0.45	GO:0007166	cell surface receptor signaling pathway
0.44	GO:0048731	system development
0.43	GO:0036211	protein modification process
0.43	GO:0035924	cellular response to vascular endothelial growth factor stimulus
0.43	GO:0030154	cell differentiation
0.41	GO:0044267	cellular protein metabolic process
0.41	GO:0006928	movement of cell or subcellular component
0.40	GO:0006796	phosphate-containing compound metabolic process
0.40	GO:0009653	anatomical structure morphogenesis
0.40	GO:0006508	proteolysis

0.53	GO:0005509	calcium ion binding
0.45	GO:0140096	catalytic activity, acting on a protein
0.44	GO:0004888	transmembrane signaling receptor activity
0.41	GO:0016791	phosphatase activity
0.40	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.40	GO:0016301	kinase activity
0.39	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.39	GO:0097367	carbohydrate derivative binding
0.38	GO:0008144	drug binding
0.38	GO:0030554	adenyl nucleotide binding

0.41	GO:0005576	extracellular region
0.40	GO:0099568	cytoplasmic region
0.39	GO:0030054	cell junction
0.39	GO:0005887	integral component of plasma membrane
0.38	GO:0120025	plasma membrane bounded cell projection
0.37	GO:0031252	cell leading edge
0.37	GO:0044463	cell projection part
0.36	GO:0098590	plasma membrane region
0.36	GO:0097458	neuron part
0.35	GO:0044430	cytoskeletal part

0.41

EC:3.1.3 EC:3.1.3.41

GO:0016791

tr|T1FRI2|T1FRI2_HELRO
Uncharacterized protein
Search

0.70	GO:0018108	peptidyl-tyrosine phosphorylation
0.39	GO:0006182	cGMP biosynthetic process
0.39	GO:0016573	histone acetylation
0.38	GO:0016567	protein ubiquitination
0.38	GO:0006813	potassium ion transport
0.36	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:1903506	regulation of nucleic acid-templated transcription
0.35	GO:0010468	regulation of gene expression

0.70	GO:0004713	protein tyrosine kinase activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0004674	protein serine/threonine kinase activity
0.40	GO:0004383	guanylate cyclase activity
0.39	GO:0004402	histone acetyltransferase activity
0.39	GO:0019199	transmembrane receptor protein kinase activity
0.38	GO:0004842	ubiquitin-protein transferase activity
0.37	GO:0032550	purine ribonucleoside binding

0.34	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.70	EC:2.7.10	GO:0004713
0.38	KEGG:R03876	GO:0004842

tr|T1FRI3|T1FRI3_HELRO
Uncharacterized protein
Search

tr|T1FRI4|T1FRI4_HELRO
Uncharacterized protein
Search

tr|T1FRI5|T1FRI5_HELRO
Uncharacterized protein
Search

tr|T1FRI6|T1FRI6_HELRO
Uncharacterized protein
Search

tr|T1FRI7|T1FRI7_HELRO
Uncharacterized protein
Search

tr|T1FRI8|T1FRI8_HELRO
Uncharacterized protein
Search

tr|T1FRI9|T1FRI9_HELRO
Uncharacterized protein
Search

0.47	GO:0006338	chromatin remodeling
0.43	GO:0014017	neuroblast fate commitment
0.43	GO:0048085	adult chitin-containing cuticle pigmentation
0.43	GO:0007406	negative regulation of neuroblast proliferation
0.43	GO:0048190	wing disc dorsal/ventral pattern formation
0.43	GO:0008586	imaginal disc-derived wing vein morphogenesis
0.43	GO:0008587	imaginal disc-derived wing margin morphogenesis
0.43	GO:0007379	segment specification
0.43	GO:0007480	imaginal disc-derived leg morphogenesis
0.42	GO:0042058	regulation of epidermal growth factor receptor signaling pathway

0.57	GO:0005544	calcium-dependent phospholipid binding
0.52	GO:0005509	calcium ion binding
0.39	GO:0003676	nucleic acid binding
0.35	GO:0005096	GTPase activator activity
0.34	GO:0008270	zinc ion binding
0.34	GO:0030246	carbohydrate binding
0.33	GO:0005515	protein binding
0.33	GO:0004672	protein kinase activity
0.33	GO:0016775	phosphotransferase activity, nitrogenous group as acceptor
0.33	GO:0030554	adenyl nucleotide binding

0.47	GO:0070603	SWI/SNF superfamily-type complex
0.36	GO:0030117	membrane coat
0.35	GO:0012507	ER to Golgi transport vesicle membrane
0.33	GO:0005654	nucleoplasm
0.32	GO:0005829	cytosol
0.32	GO:0005739	mitochondrion
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.33

GO:0016775

tr|T1FRJ0|T1FRJ0_HELRO
Uncharacterized protein
Search

tr|T1FRJ1|T1FRJ1_HELRO
Uncharacterized protein
Search

0.58	GO:0006508	proteolysis
0.36	GO:0032446	protein modification by small protein conjugation
0.35	GO:0048804	imaginal disc-derived female genitalia morphogenesis
0.35	GO:0007394	dorsal closure, elongation of leading edge cells
0.35	GO:0048803	imaginal disc-derived male genitalia morphogenesis
0.35	GO:0046528	imaginal disc fusion
0.35	GO:0007256	activation of JNKK activity
0.35	GO:0030154	cell differentiation
0.35	GO:0071361	cellular response to ethanol
0.35	GO:0007257	activation of JUN kinase activity

0.64	GO:0008236	serine-type peptidase activity
0.38	GO:0004177	aminopeptidase activity
0.36	GO:0004842	ubiquitin-protein transferase activity
0.36	GO:0005525	GTP binding
0.35	GO:0004706	JUN kinase kinase kinase activity
0.35	GO:0001085	RNA polymerase II transcription factor binding
0.35	GO:0046872	metal ion binding
0.34	GO:0003677	DNA binding
0.34	GO:0004175	endopeptidase activity
0.34	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding

0.35	GO:0005634	nucleus
0.34	GO:0005667	transcription factor complex
0.34	GO:0005938	cell cortex
0.34	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.38	EC:3.4.11	GO:0004177
0.36	KEGG:R03876	GO:0004842

tr|T1FRJ2|T1FRJ2_HELRO
Uncharacterized protein
Search

0.47	GO:0048015	phosphatidylinositol-mediated signaling
0.47	GO:0046854	phosphatidylinositol phosphorylation
0.45	GO:0006325	chromatin organization
0.43	GO:0043412	macromolecule modification
0.42	GO:0019538	protein metabolic process
0.41	GO:2001141	regulation of RNA biosynthetic process
0.41	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.41	GO:0010468	regulation of gene expression
0.41	GO:0036098	male germ-line stem cell population maintenance
0.40	GO:0030717	karyosome formation

0.44	GO:0140096	catalytic activity, acting on a protein
0.43	GO:0003676	nucleic acid binding
0.43	GO:0016301	kinase activity
0.41	GO:0016407	acetyltransferase activity
0.41	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.40	GO:0005230	extracellular ligand-gated ion channel activity
0.39	GO:0032451	demethylase activity
0.39	GO:0030554	adenyl nucleotide binding
0.39	GO:0097367	carbohydrate derivative binding
0.39	GO:0008144	drug binding

0.47	GO:0044454	nuclear chromosome part
0.45	GO:0000785	chromatin
0.42	GO:1904949	ATPase complex
0.39	GO:0033202	DNA helicase complex
0.39	GO:0000118	histone deacetylase complex
0.39	GO:0000794	condensed nuclear chromosome
0.38	GO:0005856	cytoskeleton
0.36	GO:0005886	plasma membrane
0.35	GO:0043234	protein complex
0.34	GO:0005737	cytoplasm

0.41

GO:0016407

tr|T1FRJ3|T1FRJ3_HELRO
Uncharacterized protein
Search

0.55	GO:0006357	regulation of transcription by RNA polymerase II
0.48	GO:0097659	nucleic acid-templated transcription
0.46	GO:0010467	gene expression
0.45	GO:0034645	cellular macromolecule biosynthetic process
0.44	GO:0042705	ocellus photoreceptor cell differentiation
0.43	GO:0007468	regulation of rhodopsin gene expression
0.43	GO:0042052	rhabdomere development
0.40	GO:0010557	positive regulation of macromolecule biosynthetic process
0.40	GO:0031328	positive regulation of cellular biosynthetic process
0.40	GO:0010628	positive regulation of gene expression

0.59	GO:0003712	transcription cofactor activity
0.58	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.43	GO:0003676	nucleic acid binding
0.41	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.40	GO:0042802	identical protein binding
0.39	GO:0046983	protein dimerization activity
0.36	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.36	GO:0043130	ubiquitin binding
0.36	GO:0046872	metal ion binding
0.36	GO:0030674	protein binding, bridging

0.57	GO:0016592	mediator complex
0.42	GO:0000124	SAGA complex
0.38	GO:0016514	SWI/SNF complex
0.37	GO:0046695	SLIK (SAGA-like) complex
0.36	GO:0005669	transcription factor TFIID complex
0.35	GO:0005844	polysome
0.35	GO:0010494	cytoplasmic stress granule
0.35	GO:0000786	nucleosome
0.34	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.36

EC:3.1.4.17

GO:0004114

tr|T1FRJ4|T1FRJ4_HELRO
Uncharacterized protein
Search

0.52	GO:0045944	positive regulation of transcription by RNA polymerase II
0.51	GO:0035120	post-embryonic appendage morphogenesis
0.51	GO:0035114	imaginal disc-derived appendage morphogenesis
0.51	GO:0007560	imaginal disc morphogenesis
0.48	GO:0070896	positive regulation of transposon integration
0.48	GO:0006413	translational initiation
0.48	GO:0035316	non-sensory hair organization
0.47	GO:0018992	germ-line sex determination
0.47	GO:0035285	appendage segmentation
0.47	GO:0035017	cuticle pattern formation

0.49	GO:0003743	translation initiation factor activity
0.48	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.46	GO:0046983	protein dimerization activity
0.44	GO:0035800	deubiquitinase activator activity
0.42	GO:0051019	mitogen-activated protein kinase binding
0.42	GO:0008301	DNA binding, bending
0.42	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.41	GO:0017137	Rab GTPase binding
0.40	GO:0003682	chromatin binding
0.38	GO:0046872	metal ion binding

0.51	GO:0005634	nucleus
0.40	GO:0044427	chromosomal part
0.40	GO:0031248	protein acetyltransferase complex
0.40	GO:0000428	DNA-directed RNA polymerase complex
0.40	GO:0005667	transcription factor complex
0.39	GO:0070013	intracellular organelle lumen
0.39	GO:1905368	peptidase complex
0.37	GO:0005700	polytene chromosome
0.37	GO:0034707	chloride channel complex
0.33	GO:0005886	plasma membrane

0.36	EC:2.7.7	GO:0016779
0.38	KEGG:R03876	GO:0004842

tr|T1FRJ5|T1FRJ5_HELRO
Uncharacterized protein
Search

0.40	GO:0005975	carbohydrate metabolic process
0.40	GO:0036211	protein modification process
0.40	GO:0019222	regulation of metabolic process
0.39	GO:0016310	phosphorylation
0.39	GO:0043326	chemotaxis to folate
0.39	GO:0060176	regulation of aggregation involved in sorocarp development
0.38	GO:0044267	cellular protein metabolic process
0.38	GO:0043327	chemotaxis to cAMP
0.38	GO:0031272	regulation of pseudopodium assembly
0.38	GO:1903778	protein localization to vacuolar membrane

0.42	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.40	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.40	GO:0140096	catalytic activity, acting on a protein
0.40	GO:0140110	transcription regulator activity
0.40	GO:0016301	kinase activity
0.39	GO:0030554	adenyl nucleotide binding
0.39	GO:0043565	sequence-specific DNA binding
0.39	GO:0097367	carbohydrate derivative binding
0.39	GO:0008144	drug binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding

0.37	GO:0005773	vacuole
0.37	GO:0005881	cytoplasmic microtubule
0.37	GO:1990234	transferase complex
0.36	GO:0005815	microtubule organizing center
0.36	GO:0016592	mediator complex
0.36	GO:0019898	extrinsic component of membrane
0.36	GO:0098805	whole membrane
0.35	GO:0098588	bounding membrane of organelle
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.42

GO:0004553

tr|T1FRJ6|T1FRJ6_HELRO
Uncharacterized protein
Search

tr|T1FRJ7|T1FRJ7_HELRO
Uncharacterized protein
Search

0.45	GO:0060255	regulation of macromolecule metabolic process
0.45	GO:0031323	regulation of cellular metabolic process
0.45	GO:0051171	regulation of nitrogen compound metabolic process
0.45	GO:0080090	regulation of primary metabolic process
0.45	GO:0009889	regulation of biosynthetic process
0.43	GO:0048518	positive regulation of biological process
0.42	GO:0051289	protein homotetramerization
0.41	GO:0044093	positive regulation of molecular function
0.40	GO:0032502	developmental process
0.39	GO:0032501	multicellular organismal process

0.44	GO:0008270	zinc ion binding
0.43	GO:0008140	cAMP response element binding protein binding
0.42	GO:0140110	transcription regulator activity
0.41	GO:0003676	nucleic acid binding
0.39	GO:0046983	protein dimerization activity
0.39	GO:0017076	purine nucleotide binding
0.39	GO:0097367	carbohydrate derivative binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0016874	ligase activity
0.38	GO:0008144	drug binding

0.48	GO:0005634	nucleus
0.39	GO:0005700	polytene chromosome
0.38	GO:0043233	organelle lumen
0.37	GO:0032991	macromolecular complex
0.37	GO:0044446	intracellular organelle part
0.36	GO:0005737	cytoplasm
0.35	GO:0015629	actin cytoskeleton
0.35	GO:0099512	supramolecular fiber
0.34	GO:0000131	incipient cellular bud site
0.34	GO:0005934	cellular bud tip

0.38

GO:0016874

tr|T1FRJ8|T1FRJ8_HELRO
Uncharacterized protein
Search

tr|T1FRJ9|T1FRJ9_HELRO
Uncharacterized protein
Search

tr|T1FRK0|T1FRK0_HELRO
Uncharacterized protein
Search

0.41

GO:0007018

microtubule-based movement

0.41	GO:0003777	microtubule motor activity
0.41	GO:0008017	microtubule binding
0.37	GO:0008270	zinc ion binding
0.36	GO:0030554	adenyl nucleotide binding
0.36	GO:0097367	carbohydrate derivative binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0031224

intrinsic component of membrane

tr|T1FRK1|T1FRK1_HELRO
Uncharacterized protein
Search

0.49	GO:0043972	histone H3-K23 acetylation
0.43	GO:0045893	positive regulation of transcription, DNA-templated
0.39	GO:0070647	protein modification by small protein conjugation or removal
0.39	GO:0046486	glycerolipid metabolic process
0.38	GO:0046460	neutral lipid biosynthetic process
0.38	GO:0048015	phosphatidylinositol-mediated signaling
0.37	GO:0046834	lipid phosphorylation
0.36	GO:0006348	chromatin silencing at telomere
0.36	GO:0016070	RNA metabolic process
0.36	GO:0006644	phospholipid metabolic process

0.49	GO:0043994	histone acetyltransferase activity (H3-K23 specific)
0.46	GO:0046872	metal ion binding
0.44	GO:0003676	nucleic acid binding
0.39	GO:0004842	ubiquitin-protein transferase activity
0.38	GO:0004144	diacylglycerol O-acyltransferase activity
0.36	GO:0030554	adenyl nucleotide binding
0.36	GO:0097367	carbohydrate derivative binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0016301	kinase activity

0.47	GO:0070776	MOZ/MORF histone acetyltransferase complex
0.42	GO:0005829	cytosol
0.38	GO:0005886	plasma membrane
0.36	GO:0005783	endoplasmic reticulum
0.36	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0000781	chromosome, telomeric region
0.36	GO:0031984	organelle subcompartment
0.34	GO:0000790	nuclear chromatin
0.34	GO:0009570	chloroplast stroma
0.34	GO:0005667	transcription factor complex

0.38	EC:2.3.1.20	GO:0004144
0.39	KEGG:R03876	GO:0004842

tr|T1FRK2|T1FRK2_HELRO
Uncharacterized protein
Search

0.71	Transmembrane BAX inhibitor motif containing 1

0.51	GO:0021681	cerebellar granular layer development
0.51	GO:0021702	cerebellar Purkinje cell differentiation
0.50	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.50	GO:0002931	response to ischemia
0.49	GO:0043523	regulation of neuron apoptotic process
0.48	GO:1901215	negative regulation of neuron death
0.37	GO:0006915	apoptotic process
0.35	GO:0043044	ATP-dependent chromatin remodeling
0.34	GO:0043113	receptor clustering
0.34	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway

0.44	GO:0005544	calcium-dependent phospholipid binding
0.41	GO:0005509	calcium ion binding
0.35	GO:0043236	laminin binding
0.34	GO:0140096	catalytic activity, acting on a protein
0.34	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.33	GO:0097367	carbohydrate derivative binding
0.33	GO:0008144	drug binding
0.33	GO:0016301	kinase activity
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.48	GO:0098857	membrane microdomain
0.44	GO:0005794	Golgi apparatus
0.44	GO:0005783	endoplasmic reticulum
0.38	GO:0045211	postsynaptic membrane
0.37	GO:0030054	cell junction
0.35	GO:0016514	SWI/SNF complex
0.34	GO:0044433	cytoplasmic vesicle part
0.34	GO:0030134	COPII-coated ER to Golgi transport vesicle
0.34	GO:0005581	collagen trimer
0.34	GO:0030133	transport vesicle

0.34	EC:2.7.1	GO:0016773
0.32	KEGG:R08193	GO:0004610

tr|T1FRK3|T1FRK3_HELRO
Uncharacterized protein
Search

0.10	Ubiquitin-conjugating enzyme E2 J1

0.56	GO:1904153	negative regulation of retrograde protein transport, ER to cytosol
0.56	GO:0042534	regulation of tumor necrosis factor biosynthetic process
0.54	GO:0018279	protein N-linked glycosylation via asparagine
0.53	GO:0007286	spermatid development
0.53	GO:0030433	ubiquitin-dependent ERAD pathway
0.50	GO:0016567	protein ubiquitination

0.55	GO:0061631	ubiquitin conjugating enzyme activity
0.53	GO:0031625	ubiquitin protein ligase binding
0.43	GO:0061630	ubiquitin protein ligase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.36	GO:0005737	cytoplasm
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0031984	organelle subcompartment
0.33	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

tr|T1FRK4|T1FRK4_HELRO
Uncharacterized protein
Search

0.57	GO:0000746	conjugation
0.45	GO:0045944	positive regulation of transcription by RNA polymerase II
0.42	GO:0006351	transcription, DNA-templated
0.39	GO:0006413	translational initiation
0.39	GO:0009272	fungal-type cell wall biogenesis
0.38	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.37	GO:0006338	chromatin remodeling
0.37	GO:0007165	signal transduction
0.37	GO:0007512	adult heart development
0.37	GO:1904707	positive regulation of vascular smooth muscle cell proliferation

0.45	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.42	GO:0046983	protein dimerization activity
0.40	GO:0008270	zinc ion binding
0.39	GO:0003743	translation initiation factor activity
0.39	GO:0004697	protein kinase C activity
0.37	GO:0003682	chromatin binding
0.37	GO:0005509	calcium ion binding
0.36	GO:0008233	peptidase activity
0.36	GO:0000339	RNA cap binding
0.36	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding

0.45	GO:0005634	nucleus
0.41	GO:0070013	intracellular organelle lumen
0.39	GO:0044446	intracellular organelle part
0.38	GO:0000428	DNA-directed RNA polymerase complex
0.38	GO:0005667	transcription factor complex
0.37	GO:0043232	intracellular non-membrane-bounded organelle
0.35	GO:0030686	90S preribosome
0.35	GO:0030687	preribosome, large subunit precursor
0.35	GO:1904949	ATPase complex
0.35	GO:0005886	plasma membrane

0.39

EC:2.7.11.13

GO:0004697

tr|T1FRK5|T1FRK5_HELRO
Uncharacterized protein
Search

0.75	Core 1 udp-galactose:n-acetylgalactosamine-alpha-r beta galactosyltransferase

0.73	GO:0016266	O-glycan processing
0.35	GO:0060576	intestinal epithelial cell development
0.34	GO:0001525	angiogenesis
0.33	GO:0006508	proteolysis
0.32	GO:0055085	transmembrane transport

0.73	GO:0016263	glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity
0.33	GO:0004252	serine-type endopeptidase activity
0.33	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.32	GO:0046872	metal ion binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0016020

membrane

0.73

EC:2.4.1.122

GO:0016263

tr|T1FRK6|T1FRK6_HELRO
Uncharacterized protein
Search

tr|T1FRK7|T1FRK7_HELRO
Uncharacterized protein
Search

LCMT1

0.64	Leucine carboxyl methyltransferase

0.63	GO:0032259	methylation
0.42	GO:0018410	C-terminal protein amino acid modification
0.40	GO:0008213	protein alkylation
0.36	GO:0090266	regulation of mitotic cell cycle spindle assembly checkpoint
0.35	GO:0010906	regulation of glucose metabolic process
0.35	GO:0031333	negative regulation of protein complex assembly
0.34	GO:0042981	regulation of apoptotic process

0.63	GO:0008168	methyltransferase activity
0.37	GO:0140096	catalytic activity, acting on a protein

0.39	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.63

GO:0008168

tr|T1FRK8|T1FRK8_HELRO
Uncharacterized protein
Search

tr|T1FRK9|T1FRK9_HELRO
Uncharacterized protein
Search

0.63	GO:0097120	receptor localization to synapse
0.62	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity
0.62	GO:0043113	receptor clustering
0.58	GO:0046710	GDP metabolic process
0.56	GO:0046037	GMP metabolic process
0.55	GO:0007399	nervous system development
0.52	GO:0007268	chemical synaptic transmission
0.48	GO:0043412	macromolecule modification
0.45	GO:0016311	dephosphorylation
0.45	GO:0044267	cellular protein metabolic process

0.64	GO:0035255	ionotropic glutamate receptor binding
0.58	GO:0004385	guanylate kinase activity
0.47	GO:0004721	phosphoprotein phosphatase activity
0.41	GO:0004835	tubulin-tyrosine ligase activity
0.41	GO:0004672	protein kinase activity
0.40	GO:0004842	ubiquitin-protein transferase activity
0.39	GO:0032559	adenyl ribonucleotide binding
0.39	GO:0008144	drug binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0008168	methyltransferase activity

0.60	GO:0016323	basolateral plasma membrane
0.58	GO:0045211	postsynaptic membrane
0.56	GO:0008328	ionotropic glutamate receptor complex
0.55	GO:0014069	postsynaptic density
0.44	GO:0042622	photoreceptor outer segment membrane
0.43	GO:0001917	photoreceptor inner segment
0.40	GO:0032039	integrator complex

0.58	EC:2.7.4.8	GO:0004385
0.40	KEGG:R03876	GO:0004842

tr|T1FRL0|T1FRL0_HELRO
Uncharacterized protein
Search

LOC108734237

0.64	Methenyltetrahydrofolate synthetase domain containing

0.50

GO:0008298

intracellular mRNA localization

0.55	GO:0003723	RNA binding
0.39	GO:0016874	ligase activity

0.37	GO:0005737	cytoplasm
0.33	GO:1990904	ribonucleoprotein complex
0.33	GO:0043232	intracellular non-membrane-bounded organelle

0.39

GO:0016874

tr|T1FRL1|T1FRL1_HELRO
Uncharacterized protein
Search

tr|T1FRL2|T1FRL2_HELRO
Uncharacterized protein
Search

0.44	GO:0035023	regulation of Rho protein signal transduction
0.41	GO:0065009	regulation of molecular function
0.40	GO:0006357	regulation of transcription by RNA polymerase II
0.39	GO:0016310	phosphorylation
0.39	GO:0007416	synapse assembly
0.39	GO:0007162	negative regulation of cell adhesion
0.39	GO:0010467	gene expression
0.38	GO:0030522	intracellular receptor signaling pathway
0.38	GO:0016070	RNA metabolic process
0.38	GO:0043401	steroid hormone mediated signaling pathway

0.44	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.44	GO:0050825	ice binding
0.41	GO:0008270	zinc ion binding
0.40	GO:0003700	DNA binding transcription factor activity
0.40	GO:0016772	transferase activity, transferring phosphorus-containing groups
0.40	GO:0003676	nucleic acid binding
0.39	GO:0032559	adenyl ribonucleotide binding
0.39	GO:0043168	anion binding
0.39	GO:0008144	drug binding
0.39	GO:0003707	steroid hormone receptor activity

0.40	GO:0005634	nucleus
0.39	GO:0072588	box H/ACA RNP complex
0.39	GO:0048786	presynaptic active zone
0.38	GO:0000015	phosphopyruvate hydratase complex
0.36	GO:0070013	intracellular organelle lumen
0.35	GO:0043232	intracellular non-membrane-bounded organelle
0.35	GO:0044446	intracellular organelle part
0.35	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.40

EC:2.7

GO:0016772

tr|T1FRL3|T1FRL3_HELRO
Uncharacterized protein
Search

0.56	GO:1990872	negative regulation of sterol import by negative regulation of transcription from RNA polymerase II promoter
0.54	GO:0035376	sterol import
0.53	GO:0000011	vacuole inheritance
0.52	GO:0042307	positive regulation of protein import into nucleus
0.52	GO:0031106	septin ring organization
0.51	GO:0007096	regulation of exit from mitosis
0.51	GO:0019236	response to pheromone
0.43	GO:0006468	protein phosphorylation
0.42	GO:0005975	carbohydrate metabolic process

0.51	GO:0030248	cellulose binding
0.46	GO:0004674	protein serine/threonine kinase activity
0.44	GO:0003700	DNA binding transcription factor activity
0.40	GO:0003677	DNA binding
0.40	GO:0032559	adenyl ribonucleotide binding
0.40	GO:0008144	drug binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding

0.51	GO:0005933	cellular bud
0.50	GO:0000324	fungal-type vacuole
0.48	GO:0005634	nucleus
0.45	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.46

GO:0004674

tr|T1FRL4|T1FRL4_HELRO
Uncharacterized protein
Search

0.46	GO:0016567	protein ubiquitination
0.38	GO:0006468	protein phosphorylation
0.37	GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.37	GO:0032456	endocytic recycling
0.37	GO:0007030	Golgi organization
0.37	GO:0006478	peptidyl-tyrosine sulfation
0.37	GO:0042147	retrograde transport, endosome to Golgi
0.36	GO:0048193	Golgi vesicle transport
0.36	GO:0060255	regulation of macromolecule metabolic process
0.35	GO:0007186	G-protein coupled receptor signaling pathway

0.46	GO:0004842	ubiquitin-protein transferase activity
0.39	GO:0046872	metal ion binding
0.38	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.38	GO:0016301	kinase activity
0.37	GO:0030248	cellulose binding
0.37	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups
0.37	GO:0008476	protein-tyrosine sulfotransferase activity
0.37	GO:0003676	nucleic acid binding
0.37	GO:0009678	hydrogen-translocating pyrophosphatase activity
0.37	GO:0031683	G-protein beta/gamma-subunit complex binding

0.38	GO:0005634	nucleus
0.38	GO:1990745	EARP complex
0.38	GO:0000938	GARP complex
0.37	GO:0030686	90S preribosome
0.36	GO:0031461	cullin-RING ubiquitin ligase complex
0.35	GO:0005829	cytosol
0.35	GO:0031974	membrane-enclosed lumen
0.35	GO:0005576	extracellular region
0.34	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

0.38	EC:2.7.1	GO:0016773
0.46	KEGG:R03876	GO:0004842

tr|T1FRL5|T1FRL5_HELRO
Uncharacterized protein
Search

tr|T1FRL6|T1FRL6_HELRO
Uncharacterized protein
Search

tr|T1FRL7|T1FRL7_HELRO
Uncharacterized protein
Search

tr|T1FRL8|T1FRL8_HELRO
Uncharacterized protein
Search

ARMT1

0.61	Acidic residue methyltransferase 1

0.64	GO:2001020	regulation of response to DNA damage stimulus
0.61	GO:0008213	protein alkylation
0.57	GO:0032259	methylation
0.48	GO:0016311	dephosphorylation
0.41	GO:0043401	steroid hormone mediated signaling pathway
0.38	GO:0006974	cellular response to DNA damage stimulus
0.37	GO:0006351	transcription, DNA-templated
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:0010468	regulation of gene expression

0.65	GO:0051998	protein carboxyl O-methyltransferase activity
0.58	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity
0.54	GO:0019899	enzyme binding
0.48	GO:0016791	phosphatase activity
0.44	GO:0030284	estrogen receptor activity
0.42	GO:0005496	steroid binding
0.38	GO:0043565	sequence-specific DNA binding
0.38	GO:0008270	zinc ion binding
0.37	GO:0003700	DNA binding transcription factor activity
0.36	GO:0071949	FAD binding

0.39	GO:0005634	nucleus
0.37	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.48

EC:3.1.3 EC:3.1.3.41

GO:0016791

tr|T1FRL9|T1FRL9_HELRO
Uncharacterized protein
Search

0.10	Zinc finger SWIM-type containing 8

0.34	GO:0006898	receptor-mediated endocytosis
0.33	GO:0006508	proteolysis

0.63	GO:0008270	zinc ion binding
0.35	GO:0005044	scavenger receptor activity
0.34	GO:0004252	serine-type endopeptidase activity

0.32	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.34

GO:0004252

tr|T1FRM0|T1FRM0_HELRO
Uncharacterized protein
Search

0.47	GO:0016998	cell wall macromolecule catabolic process
0.46	GO:0009253	peptidoglycan catabolic process
0.45	GO:0007605	sensory perception of sound
0.44	GO:0000416	positive regulation of histone H3-K36 methylation
0.44	GO:0060717	chorion development
0.44	GO:0048304	positive regulation of isotype switching to IgG isotypes
0.44	GO:0051571	positive regulation of histone H3-K4 methylation
0.43	GO:0060612	adipose tissue development
0.43	GO:0030330	DNA damage response, signal transduction by p53 class mediator
0.43	GO:0045332	phospholipid translocation

0.49	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.49	GO:0008061	chitin binding
0.46	GO:0030246	carbohydrate binding
0.45	GO:0061783	peptidoglycan muralytic activity
0.44	GO:0005201	extracellular matrix structural constituent
0.43	GO:0004012	phospholipid-translocating ATPase activity
0.42	GO:0003712	transcription cofactor activity
0.41	GO:0016301	kinase activity
0.41	GO:0005509	calcium ion binding
0.39	GO:0000287	magnesium ion binding

0.44	GO:0032040	small-subunit processome
0.44	GO:0044451	nucleoplasm part
0.43	GO:1990234	transferase complex
0.42	GO:0005578	proteinaceous extracellular matrix
0.41	GO:1905368	peptidase complex
0.38	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.49

GO:0004553

tr|T1FRM1|T1FRM1_HELRO
Uncharacterized protein
Search

0.41	GO:0006357	regulation of transcription by RNA polymerase II
0.41	GO:0007275	multicellular organism development
0.39	GO:2000144	positive regulation of DNA-templated transcription, initiation
0.39	GO:0016578	histone deubiquitination
0.38	GO:0065009	regulation of molecular function
0.38	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.38	GO:0002009	morphogenesis of an epithelium
0.38	GO:0035023	regulation of Rho protein signal transduction
0.38	GO:0010467	gene expression
0.38	GO:0090304	nucleic acid metabolic process

0.42	GO:0046872	metal ion binding
0.42	GO:0016887	ATPase activity
0.40	GO:0030554	adenyl nucleotide binding
0.40	GO:0003700	DNA binding transcription factor activity
0.40	GO:0003677	DNA binding
0.40	GO:0097367	carbohydrate derivative binding
0.40	GO:0008144	drug binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0098772	molecular function regulator
0.39	GO:0005515	protein binding

0.47	GO:0005634	nucleus
0.46	GO:0031248	protein acetyltransferase complex
0.45	GO:1905368	peptidase complex
0.43	GO:0070013	intracellular organelle lumen
0.42	GO:0044446	intracellular organelle part
0.41	GO:0043234	protein complex
0.39	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.39	GO:0005783	endoplasmic reticulum
0.37	GO:0097505	Rad6-Rad18 complex
0.36	GO:0005829	cytosol

0.42

GO:0016887

tr|T1FRM2|T1FRM2_HELRO
Uncharacterized protein
Search

DDX21

0.94	DEAD (Asp-Glu-Ala-Asp) box polypeptide 21

0.63	GO:0043330	response to exogenous dsRNA
0.61	GO:0006366	transcription by RNA polymerase II
0.58	GO:0009615	response to virus
0.53	GO:0010501	RNA secondary structure unwinding

0.71	GO:0097322	7SK snRNA binding
0.69	GO:0035198	miRNA binding
0.67	GO:0004386	helicase activity
0.65	GO:0030515	snoRNA binding
0.62	GO:0008186	RNA-dependent ATPase activity
0.58	GO:0003725	double-stranded RNA binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0019843	rRNA binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005634	nucleus
0.56	GO:0031974	membrane-enclosed lumen
0.50	GO:0043232	intracellular non-membrane-bounded organelle
0.49	GO:0044446	intracellular organelle part
0.38	GO:0005737	cytoplasm

tr|T1FRM3|T1FRM3_HELRO
Uncharacterized protein
Search

tr|T1FRM4|T1FRM4_HELRO
Uncharacterized protein
Search

0.77	GO:0006816	calcium ion transport
0.74	GO:0051283	negative regulation of sequestering of calcium ion
0.72	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.61	GO:0051649	establishment of localization in cell
0.60	GO:0034220	ion transmembrane transport

0.74	GO:0015278	calcium-release channel activity
0.66	GO:0005509	calcium ion binding

0.30	GO:0016020	membrane
0.30	GO:0005623	cell

tr|T1FRM5|T1FRM5_HELRO
Uncharacterized protein
Search

0.58	GO:0023052	signaling
0.57	GO:0007154	cell communication
0.56	GO:0045087	innate immune response
0.54	GO:0051716	cellular response to stimulus
0.51	GO:0007625	grooming behavior
0.51	GO:0065007	biological regulation
0.51	GO:0021756	striatum development
0.49	GO:0048813	dendrite morphogenesis
0.48	GO:0043588	skin development
0.48	GO:0030534	adult behavior

0.37	GO:0099103	channel activator activity
0.37	GO:0015459	potassium channel regulator activity
0.36	GO:0004860	protein kinase inhibitor activity
0.36	GO:0044325	ion channel binding
0.35	GO:0005249	voltage-gated potassium channel activity
0.35	GO:0004721	phosphoprotein phosphatase activity
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0032561	guanyl ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.47	GO:0043235	receptor complex
0.35	GO:0008076	voltage-gated potassium channel complex
0.35	GO:0005578	proteinaceous extracellular matrix
0.35	GO:0005615	extracellular space
0.32	GO:0005737	cytoplasm

0.35

GO:0004721

tr|T1FRM6|T1FRM6_HELRO
Uncharacterized protein
Search

tr|T1FRM7|T1FRM7_HELRO
Uncharacterized protein
Search

tr|T1FRM8|T1FRM8_HELRO
Uncharacterized protein
Search

tr|T1FRM9|T1FRM9_HELRO
Uncharacterized protein
Search

tr|T1FRN0|T1FRN0_HELRO
Uncharacterized protein
Search

tr|T1FRN1|T1FRN1_HELRO
Uncharacterized protein
Search

tr|T1FRN2|T1FRN2_HELRO
Uncharacterized protein
Search

0.76	GO:0034968	histone lysine methylation
0.56	GO:0018027	peptidyl-lysine dimethylation
0.54	GO:1903709	uterine gland development
0.54	GO:1903699	tarsal gland development
0.53	GO:0002674	negative regulation of acute inflammatory response
0.53	GO:0061038	uterus morphogenesis
0.53	GO:0032635	interleukin-6 production
0.51	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling
0.50	GO:0097722	sperm motility
0.50	GO:0019953	sexual reproduction

0.77	GO:0003682	chromatin binding
0.77	GO:0018024	histone-lysine N-methyltransferase activity
0.53	GO:0046872	metal ion binding
0.50	GO:0003677	DNA binding
0.43	GO:0035035	histone acetyltransferase binding
0.40	GO:0042802	identical protein binding
0.36	GO:0140034	methylation-dependent protein binding
0.35	GO:0042393	histone binding
0.34	GO:0008641	ubiquitin-like modifier activating enzyme activity
0.34	GO:0004842	ubiquitin-protein transferase activity

0.61	GO:0005634	nucleus
0.48	GO:0070013	intracellular organelle lumen
0.47	GO:0000785	chromatin
0.46	GO:0005794	Golgi apparatus
0.43	GO:0005700	polytene chromosome
0.41	GO:1904949	ATPase complex
0.37	GO:0070062	extracellular exosome
0.37	GO:0043234	protein complex
0.36	GO:0005923	bicellular tight junction
0.30	GO:0016020	membrane

0.77	EC:2.1.1.43	GO:0018024
0.34	KEGG:R03876	GO:0004842

tr|T1FRN3|T1FRN3_HELRO
Uncharacterized protein
Search

tr|T1FRN4|T1FRN4_HELRO
Uncharacterized protein
Search

0.76	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.68	GO:0000479	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.66	GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.65	GO:0000967	rRNA 5'-end processing
0.41	GO:0016569	covalent chromatin modification
0.40	GO:0007275	multicellular organism development
0.40	GO:0035690	cellular response to drug
0.40	GO:0006568	tryptophan metabolic process

0.61	GO:0042802	identical protein binding
0.42	GO:0004640	phosphoribosylanthranilate isomerase activity
0.42	GO:0004425	indole-3-glycerol-phosphate synthase activity
0.38	GO:0003723	RNA binding

0.74	GO:0032040	small-subunit processome
0.69	GO:0005730	nucleolus
0.30	GO:0016020	membrane

0.42	EC:5.3.1.24	GO:0004640
0.42	KEGG:R03509	GO:0004640

tr|T1FRN5|T1FRN5_HELRO
Uncharacterized protein
Search

tr|T1FRN6|T1FRN6_HELRO
Uncharacterized protein
Search

0.48	GO:0036211	protein modification process
0.46	GO:0046854	phosphatidylinositol phosphorylation
0.45	GO:0044267	cellular protein metabolic process
0.45	GO:0000128	flocculation
0.37	GO:1904059	regulation of locomotor rhythm
0.37	GO:0045314	regulation of compound eye photoreceptor development
0.37	GO:0030725	germline ring canal formation
0.37	GO:0035317	imaginal disc-derived wing hair organization
0.36	GO:0007391	dorsal closure
0.36	GO:0048675	axon extension

0.48	GO:0004842	ubiquitin-protein transferase activity
0.48	GO:0016307	phosphatidylinositol phosphate kinase activity
0.47	GO:0005509	calcium ion binding
0.46	GO:0019901	protein kinase binding
0.45	GO:0004672	protein kinase activity
0.43	GO:0032559	adenyl ribonucleotide binding
0.43	GO:0008144	drug binding
0.43	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0030306	ADP-ribosylation factor binding
0.38	GO:0003723	RNA binding

0.36	GO:0045179	apical cortex
0.36	GO:0043296	apical junction complex
0.34	GO:0005694	chromosome
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.48	EC:2.7.1	GO:0016307
0.48	KEGG:R03876	GO:0004842

tr|T1FRN7|T1FRN7_HELRO
Uncharacterized protein
Search

0.76	GO:0009967	positive regulation of signal transduction
0.61	GO:0007165	signal transduction

0.85

GO:0005070

SH3/SH2 adaptor activity

tr|T1FRN8|T1FRN8_HELRO
Calcium-transporting ATPase
Search

0.59	Calcium-transporting ATPase

0.77	GO:0070588	calcium ion transmembrane transport
0.69	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.41	GO:0006874	cellular calcium ion homeostasis
0.38	GO:0034505	tooth mineralization
0.38	GO:0048919	posterior lateral line neuromast development
0.38	GO:0048840	otolith development
0.38	GO:0030282	bone mineralization
0.37	GO:0060119	inner ear receptor cell development
0.37	GO:0060349	bone morphogenesis
0.37	GO:0007605	sensory perception of sound

0.80	GO:0005388	calcium-transporting ATPase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0030165	PDZ domain binding

0.38	GO:0005887	integral component of plasma membrane
0.36	GO:0043231	intracellular membrane-bounded organelle

0.80

EC:3.6.3.8

GO:0005388

tr|T1FRN9|T1FRN9_HELRO
Uncharacterized protein
Search

tr|T1FRP0|T1FRP0_HELRO
Uncharacterized protein
Search

tr|T1FRP1|T1FRP1_HELRO
Uncharacterized protein
Search

ERLIN1

0.93	Endoplasmic reticulum lipid raft-associated protein 2

0.82	GO:0030433	ubiquitin-dependent ERAD pathway
0.62	GO:0045541	negative regulation of cholesterol biosynthetic process
0.62	GO:0032933	SREBP signaling pathway
0.58	GO:0045717	negative regulation of fatty acid biosynthetic process
0.44	GO:0008203	cholesterol metabolic process
0.37	GO:0007252	I-kappaB phosphorylation
0.36	GO:0032006	regulation of TOR signaling
0.34	GO:1902741	positive regulation of interferon-alpha secretion
0.34	GO:0038061	NIK/NF-kappaB signaling
0.34	GO:0071276	cellular response to cadmium ion

0.79	GO:0031625	ubiquitin protein ligase binding
0.56	GO:0015485	cholesterol binding
0.39	GO:0008233	peptidase activity
0.37	GO:0008384	IkappaB kinase activity
0.34	GO:0097110	scaffold protein binding
0.34	GO:0070330	aromatase activity
0.34	GO:0004713	protein tyrosine kinase activity
0.33	GO:0042803	protein homodimerization activity
0.33	GO:0046982	protein heterodimerization activity
0.33	GO:0032559	adenyl ribonucleotide binding

0.70	GO:0005783	endoplasmic reticulum
0.54	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.52	GO:0031984	organelle subcompartment
0.49	GO:0045121	membrane raft
0.45	GO:0043234	protein complex
0.45	GO:0005829	cytosol
0.40	GO:0005886	plasma membrane
0.35	GO:0070062	extracellular exosome
0.33	GO:0005654	nucleoplasm
0.30	GO:0016021	integral component of membrane

0.39