Queries 15001 to 16000

GO:0016773

tr|T1FL01|T1FL01_HELRO
Uncharacterized protein
Search

0.61

GO:0007165

signal transduction

tr|T1FL02|T1FL02_HELRO
Uncharacterized protein
Search

0.43	GO:0060255	regulation of macromolecule metabolic process
0.42	GO:0090304	nucleic acid metabolic process
0.42	GO:0033554	cellular response to stress
0.42	GO:0070647	protein modification by small protein conjugation or removal
0.42	GO:0051171	regulation of nitrogen compound metabolic process
0.42	GO:0031326	regulation of cellular biosynthetic process
0.42	GO:0080090	regulation of primary metabolic process
0.42	GO:0006511	ubiquitin-dependent protein catabolic process
0.40	GO:0031325	positive regulation of cellular metabolic process
0.40	GO:0032200	telomere organization

0.50	GO:0030246	carbohydrate binding
0.42	GO:0003677	DNA binding
0.40	GO:0140110	transcription regulator activity
0.40	GO:0003682	chromatin binding
0.40	GO:0000285	1-phosphatidylinositol-3-phosphate 5-kinase activity
0.39	GO:0005515	protein binding
0.39	GO:0003727	single-stranded RNA binding
0.38	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.37	GO:0030554	adenyl nucleotide binding
0.37	GO:0097367	carbohydrate derivative binding

0.47	GO:0005634	nucleus
0.40	GO:0000781	chromosome, telomeric region
0.37	GO:0032991	macromolecular complex
0.37	GO:0070013	intracellular organelle lumen
0.36	GO:0000785	chromatin
0.36	GO:0012507	ER to Golgi transport vesicle membrane
0.35	GO:0000922	spindle pole
0.35	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0005815	microtubule organizing center
0.35	GO:0048475	coated membrane

0.40	EC:2.7.1.150	GO:0000285
0.40	KEGG:R05802	GO:0000285

tr|T1FL03|T1FL03_HELRO
Uncharacterized protein
Search

tr|T1FL04|T1FL04_HELRO
Uncharacterized protein
Search

RFX4

0.94	transcription factor RFX4

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.44	GO:0021914	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning
0.42	GO:0021516	dorsal spinal cord development
0.41	GO:0021696	cerebellar cortex morphogenesis
0.41	GO:0060271	cilium assembly
0.41	GO:0030901	midbrain development
0.40	GO:0021537	telencephalon development
0.40	GO:0006366	transcription by RNA polymerase II

0.55	GO:0003677	DNA binding
0.42	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.42	GO:0001067	regulatory region nucleic acid binding
0.39	GO:0003682	chromatin binding
0.36	GO:0005515	protein binding

0.37

GO:0005634

nucleus

tr|T1FL05|T1FL05_HELRO
Uncharacterized protein
Search

0.58	Myohemerythrin

0.40	GO:0015671	oxygen transport
0.35	GO:0007165	signal transduction
0.35	GO:0006935	chemotaxis

0.62	GO:0005506	iron ion binding
0.40	GO:0005344	oxygen carrier activity
0.35	GO:0004871	signal transducer activity

0.30

GO:0044425

membrane part

tr|T1FL06|T1FL06_HELRO
Uncharacterized protein
Search

0.61

GO:0007165

signal transduction

tr|T1FL07|T1FL07_HELRO
Uncharacterized protein
Search

0.52

GO:0035556

intracellular signal transduction

0.51

GO:0046872

metal ion binding

0.40	GO:0005622	intracellular
0.30	GO:0044425	membrane part

tr|T1FL08|T1FL08_HELRO
Uncharacterized protein
Search

tr|T1FL09|T1FL09_HELRO
Uncharacterized protein
Search

tr|T1FL10|T1FL10_HELRO
Uncharacterized protein
Search

0.41	GO:0070121	Kupffer's vesicle development
0.41	GO:0032402	melanosome transport

0.36

GO:0005515

protein binding

0.84	GO:0097546	ciliary base
0.72	GO:0030054	cell junction
0.66	GO:0005829	cytosol
0.54	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1FL11|T1FL11_HELRO
Uncharacterized protein
Search

tr|T1FL12|T1FL12_HELRO
Uncharacterized protein
Search

tr|T1FL13|T1FL13_HELRO
Uncharacterized protein
Search

tr|T1FL14|T1FL14_HELRO
Uncharacterized protein
Search

0.43	GO:0060255	regulation of macromolecule metabolic process
0.43	GO:0051171	regulation of nitrogen compound metabolic process
0.43	GO:0080090	regulation of primary metabolic process
0.43	GO:0031323	regulation of cellular metabolic process
0.43	GO:0009889	regulation of biosynthetic process
0.39	GO:0051568	histone H3-K4 methylation
0.38	GO:0097466	ubiquitin-dependent glycoprotein ERAD pathway
0.38	GO:0010467	gene expression
0.38	GO:0090304	nucleic acid metabolic process
0.37	GO:0006491	N-glycan processing

0.48	GO:0005509	calcium ion binding
0.45	GO:0003700	DNA binding transcription factor activity
0.39	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.39	GO:0003676	nucleic acid binding
0.39	GO:0016772	transferase activity, transferring phosphorus-containing groups
0.38	GO:0017016	Ras GTPase binding
0.37	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
0.36	GO:0032549	ribonucleoside binding
0.36	GO:0140098	catalytic activity, acting on RNA
0.36	GO:0004518	nuclease activity

0.41	GO:0005634	nucleus
0.38	GO:1990234	transferase complex
0.37	GO:0070013	intracellular organelle lumen
0.36	GO:0044446	intracellular organelle part
0.36	GO:0005783	endoplasmic reticulum
0.36	GO:0005604	basement membrane
0.30	GO:0016020	membrane

0.39	EC:2.7	GO:0016772
0.37	KEGG:R05982 KEGG:R06722	GO:0004571

tr|T1FL15|T1FL15_HELRO
Uncharacterized protein
Search

tr|T1FL16|T1FL16_HELRO
Uncharacterized protein
Search

tr|T1FL17|T1FL17_HELRO
Uncharacterized protein
Search

tr|T1FL18|T1FL18_HELRO
Uncharacterized protein
Search

0.53

GO:1903830

magnesium ion transmembrane transport

0.67	GO:0019706	protein-cysteine S-palmitoyltransferase activity
0.53	GO:0015095	magnesium ion transmembrane transporter activity

0.30

GO:0016021

integral component of membrane

0.67

EC:2.3.1.225

GO:0019706

tr|T1FL19|T1FL19_HELRO
Uncharacterized protein
Search

tr|T1FL21|T1FL21_HELRO
Uncharacterized protein
Search

tr|T1FL22|T1FL22_HELRO
Uncharacterized protein
Search

tr|T1FL23|T1FL23_HELRO
Uncharacterized protein
Search

0.44	GO:0060255	regulation of macromolecule metabolic process
0.44	GO:0036211	protein modification process
0.44	GO:0051171	regulation of nitrogen compound metabolic process
0.44	GO:0080090	regulation of primary metabolic process
0.44	GO:0031323	regulation of cellular metabolic process
0.44	GO:0009889	regulation of biosynthetic process
0.43	GO:0044267	cellular protein metabolic process
0.41	GO:0016310	phosphorylation
0.39	GO:0006351	transcription, DNA-templated
0.39	GO:0006996	organelle organization

0.46	GO:0003700	DNA binding transcription factor activity
0.43	GO:0004672	protein kinase activity
0.42	GO:0030554	adenyl nucleotide binding
0.41	GO:0097367	carbohydrate derivative binding
0.41	GO:0008144	drug binding
0.41	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0003676	nucleic acid binding
0.40	GO:0008270	zinc ion binding
0.39	GO:0018024	histone-lysine N-methyltransferase activity
0.38	GO:0017111	nucleoside-triphosphatase activity

0.44	GO:0005634	nucleus
0.36	GO:0005829	cytosol
0.36	GO:1902494	catalytic complex
0.35	GO:0012505	endomembrane system
0.35	GO:0005938	cell cortex
0.35	GO:0098588	bounding membrane of organelle
0.35	GO:0019898	extrinsic component of membrane
0.34	GO:0044446	intracellular organelle part
0.34	GO:0032045	guanyl-nucleotide exchange factor complex
0.34	GO:0070013	intracellular organelle lumen

0.39	EC:2.1.1.43	GO:0018024
0.36	KEGG:R05795	GO:0035005

tr|T1FL24|T1FL24_HELRO
Uncharacterized protein
Search

tr|T1FL25|T1FL25_HELRO
Uncharacterized protein
Search

tr|T1FL26|T1FL26_HELRO
Uncharacterized protein
Search

tr|T1FL27|T1FL27_HELRO
Uncharacterized protein
Search

tr|T1FL28|T1FL28_HELRO
Uncharacterized protein
Search

tr|T1FL29|T1FL29_HELRO
Uncharacterized protein
Search

tr|T1FL30|T1FL30_HELRO
Uncharacterized protein
Search

tr|T1FL31|T1FL31_HELRO
Uncharacterized protein
Search

0.70	GO:0016042	lipid catabolic process
0.35	GO:0019731	antibacterial humoral response
0.34	GO:0032049	cardiolipin biosynthetic process

0.50	GO:0016787	hydrolase activity
0.35	GO:0019904	protein domain specific binding

0.34	GO:0005815	microtubule organizing center
0.34	GO:0005615	extracellular space
0.34	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.50

GO:0016787

tr|T1FL32|T1FL32_HELRO
Uncharacterized protein
Search

tr|T1FL33|T1FL33_HELRO
Uncharacterized protein
Search

tr|T1FL34|T1FL34_HELRO
Uncharacterized protein
Search

tr|T1FL35|T1FL35_HELRO
Uncharacterized protein
Search

tr|T1FL36|T1FL36_HELRO
Uncharacterized protein
Search

tr|T1FL37|T1FL37_HELRO
Uncharacterized protein
Search

tr|T1FL38|T1FL38_HELRO
Uncharacterized protein
Search

tr|T1FL39|T1FL39_HELRO
Uncharacterized protein
Search

tr|T1FL40|T1FL40_HELRO
Uncharacterized protein
Search

tr|T1FL41|T1FL41_HELRO
Uncharacterized protein
Search

0.61	GO:1903432	regulation of TORC1 signaling
0.47	GO:0007018	microtubule-based movement

0.47	GO:0003777	microtubule motor activity
0.41	GO:0003676	nucleic acid binding
0.40	GO:0030554	adenyl nucleotide binding
0.39	GO:0097367	carbohydrate derivative binding
0.39	GO:0008144	drug binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0044425

membrane part

tr|T1FL42|T1FL42_HELRO
Uncharacterized protein
Search

tr|T1FL43|T1FL43_HELRO
Uncharacterized protein
Search

tr|T1FL44|T1FL44_HELRO
Uncharacterized protein
Search

tr|T1FL45|T1FL45_HELRO
Uncharacterized protein
Search

tr|T1FL46|T1FL46_HELRO
Uncharacterized protein
Search

0.53	GO:0006278	RNA-dependent DNA biosynthetic process
0.45	GO:0035556	intracellular signal transduction
0.44	GO:0044806	G-quadruplex DNA unwinding
0.44	GO:0032211	negative regulation of telomere maintenance via telomerase
0.44	GO:0051974	negative regulation of telomerase activity
0.42	GO:0000002	mitochondrial genome maintenance
0.41	GO:0036065	fucosylation
0.40	GO:0032508	DNA duplex unwinding
0.39	GO:0043413	macromolecule glycosylation
0.39	GO:0009101	glycoprotein biosynthetic process

0.54	GO:0003964	RNA-directed DNA polymerase activity
0.47	GO:0046872	metal ion binding
0.44	GO:0010521	telomerase inhibitor activity
0.42	GO:0043141	ATP-dependent 5'-3' DNA helicase activity
0.41	GO:0008107	galactoside 2-alpha-L-fucosyltransferase activity
0.37	GO:0043565	sequence-specific DNA binding

0.41	GO:0032580	Golgi cisterna membrane
0.40	GO:0005657	replication fork
0.40	GO:0005634	nucleus
0.37	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.54

EC:2.7.7.49

GO:0003964

tr|T1FL47|T1FL47_HELRO
Uncharacterized protein
Search

tr|T1FL48|T1FL48_HELRO
Uncharacterized protein
Search

tr|T1FL49|T1FL49_HELRO
Uncharacterized protein
Search

0.40

GO:0046872

metal ion binding

0.30

GO:0044425

membrane part

tr|T1FL50|T1FL50_HELRO
Uncharacterized protein
Search

tr|T1FL51|T1FL51_HELRO
Uncharacterized protein
Search

tr|T1FL53|T1FL53_HELRO
Uncharacterized protein
Search

tr|T1FL54|T1FL54_HELRO
Uncharacterized protein
Search

0.51

GO:0003676

nucleic acid binding

tr|T1FL55|T1FL55_HELRO
Uncharacterized protein
Search

tr|T1FL56|T1FL56_HELRO
Uncharacterized protein
Search

0.55	GO:0055085	transmembrane transport
0.34	GO:0055114	oxidation-reduction process

0.57	GO:0022857	transmembrane transporter activity
0.37	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

0.30

GO:0044425

membrane part

0.37

GO:0016705

tr|T1FL57|T1FL57_HELRO
Uncharacterized protein
Search

tr|T1FL58|T1FL58_HELRO
Uncharacterized protein
Search

0.54	GO:0007350	blastoderm segmentation
0.54	GO:0035074	pupation
0.54	GO:0035626	juvenile hormone mediated signaling pathway
0.54	GO:0035120	post-embryonic appendage morphogenesis
0.54	GO:0035114	imaginal disc-derived appendage morphogenesis
0.53	GO:0007560	imaginal disc morphogenesis
0.53	GO:0035073	pupariation
0.52	GO:0016322	neuron remodeling
0.52	GO:0016319	mushroom body development
0.51	GO:0035218	leg disc development

0.49	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.49	GO:0003707	steroid hormone receptor activity
0.48	GO:0005515	protein binding
0.48	GO:0000976	transcription regulatory region sequence-specific DNA binding
0.43	GO:0004672	protein kinase activity
0.42	GO:0008270	zinc ion binding
0.42	GO:0030552	cAMP binding
0.42	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity
0.42	GO:0015385	sodium:proton antiporter activity
0.41	GO:0045182	translation regulator activity

0.45	GO:0005634	nucleus
0.42	GO:0005913	cell-cell adherens junction
0.42	GO:0045177	apical part of cell
0.42	GO:0030688	preribosome, small subunit precursor
0.40	GO:0005667	transcription factor complex
0.39	GO:0005829	cytosol
0.39	GO:0044446	intracellular organelle part
0.39	GO:0012505	endomembrane system
0.38	GO:0005576	extracellular region
0.38	GO:0005886	plasma membrane

0.42

EC:3.1.4

GO:0004115

tr|T1FL59|T1FL59_HELRO
Uncharacterized protein
Search

tr|T1FL60|T1FL60_HELRO
Uncharacterized protein
Search

tr|T1FL61|T1FL61_HELRO
Uncharacterized protein
Search

0.67	GO:0098664	G-protein coupled serotonin receptor signaling pathway
0.53	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.48	GO:1901255	nucleotide-excision repair involved in interstrand cross-link repair
0.48	GO:0000712	resolution of meiotic recombination intermediates
0.45	GO:0000724	double-strand break repair via homologous recombination
0.42	GO:0019062	virion attachment to host cell

0.68	GO:0099589	serotonin receptor activity
0.65	GO:0099528	G-protein coupled neurotransmitter receptor activity
0.65	GO:0008227	G-protein coupled amine receptor activity
0.53	GO:0004518	nuclease activity
0.47	GO:0003677	DNA binding
0.40	GO:0140097	catalytic activity, acting on DNA

0.55	GO:0005887	integral component of plasma membrane
0.48	GO:0000110	nucleotide-excision repair factor 1 complex

0.53

GO:0004518

tr|T1FL62|T1FL62_HELRO
Uncharacterized protein
Search

0.44

GO:0046872

metal ion binding

0.30

GO:0044425

membrane part

tr|T1FL63|T1FL63_HELRO
Uncharacterized protein
Search

tr|T1FL64|T1FL64_HELRO
Uncharacterized protein
Search

0.43	GO:0036211	protein modification process
0.42	GO:0065007	biological regulation
0.42	GO:0044267	cellular protein metabolic process
0.41	GO:0016310	phosphorylation
0.39	GO:0097659	nucleic acid-templated transcription
0.39	GO:0034645	cellular macromolecule biosynthetic process
0.39	GO:0010467	gene expression
0.39	GO:0016043	cellular component organization
0.38	GO:0022414	reproductive process
0.38	GO:0007017	microtubule-based process

0.43	GO:0016772	transferase activity, transferring phosphorus-containing groups
0.42	GO:0003677	DNA binding
0.42	GO:0140096	catalytic activity, acting on a protein
0.41	GO:0097367	carbohydrate derivative binding
0.41	GO:0008144	drug binding
0.41	GO:0030554	adenyl nucleotide binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0140110	transcription regulator activity
0.40	GO:0005096	GTPase activator activity
0.37	GO:0005515	protein binding

0.45	GO:0005634	nucleus
0.42	GO:0005667	transcription factor complex
0.40	GO:0044446	intracellular organelle part
0.39	GO:1902494	catalytic complex
0.37	GO:0012505	endomembrane system
0.37	GO:0015630	microtubule cytoskeleton
0.37	GO:0070013	intracellular organelle lumen
0.36	GO:0020011	apicoplast
0.36	GO:0005911	cell-cell junction
0.36	GO:0031090	organelle membrane

0.43

EC:2.7

GO:0016772

tr|T1FL65|T1FL65_HELRO
Uncharacterized protein
Search

tr|T1FL66|T1FL66_HELRO
Uncharacterized protein
Search

0.79	GO:0007596	blood coagulation
0.62	GO:0001775	cell activation
0.60	GO:0051258	protein polymerization
0.53	GO:0010519	negative regulation of phospholipase activity
0.53	GO:0051005	negative regulation of lipoprotein lipase activity
0.53	GO:0007165	signal transduction
0.52	GO:0055091	phospholipid homeostasis
0.51	GO:0050996	positive regulation of lipid catabolic process
0.51	GO:0070328	triglyceride homeostasis
0.51	GO:0048844	artery morphogenesis

0.62	GO:0030674	protein binding, bridging
0.61	GO:0005102	receptor binding
0.51	GO:0004859	phospholipase inhibitor activity
0.48	GO:0050839	cell adhesion molecule binding
0.47	GO:0030545	receptor regulator activity
0.46	GO:0032403	protein complex binding

0.67	GO:0005577	fibrinogen complex
0.48	GO:0005769	early endosome
0.47	GO:0009986	cell surface
0.45	GO:0005794	Golgi apparatus

tr|T1FL67|T1FL67_HELRO
Uncharacterized protein
Search

tr|T1FL68|T1FL68_HELRO
Uncharacterized protein
Search

tr|T1FL69|T1FL69_HELRO
Uncharacterized protein
Search

0.44	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.44	GO:2001141	regulation of RNA biosynthetic process
0.44	GO:0010468	regulation of gene expression
0.43	GO:0036211	protein modification process
0.41	GO:0044267	cellular protein metabolic process
0.39	GO:0031156	regulation of sorocarp development
0.39	GO:0043326	chemotaxis to folate
0.38	GO:0043327	chemotaxis to cAMP
0.38	GO:0031272	regulation of pseudopodium assembly
0.37	GO:0032107	regulation of response to nutrient levels

0.45	GO:0140110	transcription regulator activity
0.43	GO:0019789	SUMO transferase activity
0.40	GO:0016874	ligase activity
0.40	GO:0003676	nucleic acid binding
0.39	GO:0004674	protein serine/threonine kinase activity
0.39	GO:0008270	zinc ion binding
0.38	GO:0030554	adenyl nucleotide binding
0.37	GO:0097367	carbohydrate derivative binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding

0.43	GO:0005634	nucleus
0.38	GO:0005815	microtubule organizing center
0.37	GO:0005881	cytoplasmic microtubule
0.36	GO:0070013	intracellular organelle lumen
0.36	GO:0005694	chromosome
0.36	GO:0032991	macromolecular complex
0.36	GO:0020011	apicoplast
0.34	GO:0005615	extracellular space
0.34	GO:0042641	actomyosin
0.34	GO:0005794	Golgi apparatus

0.40	EC:6	GO:0016874
0.37	KEGG:R03876	GO:0004842

tr|T1FL70|T1FL70_HELRO
Uncharacterized protein
Search

tr|T1FL71|T1FL71_HELRO
Uncharacterized protein
Search

tr|T1FL72|T1FL72_HELRO
Uncharacterized protein
Search

0.30

GO:0044425

membrane part

tr|T1FL73|T1FL73_HELRO
Uncharacterized protein
Search

tr|T1FL74|T1FL74_HELRO
Uncharacterized protein
Search

0.43	GO:0006325	chromatin organization
0.42	GO:0018022	peptidyl-lysine methylation
0.38	GO:0048208	COPII vesicle coating
0.38	GO:1903506	regulation of nucleic acid-templated transcription
0.38	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.38	GO:0010468	regulation of gene expression
0.36	GO:0006783	heme biosynthetic process
0.36	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.35	GO:0006352	DNA-templated transcription, initiation
0.35	GO:0035023	regulation of Rho protein signal transduction

0.44	GO:0003676	nucleic acid binding
0.44	GO:0050825	ice binding
0.43	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.39	GO:0046872	metal ion binding
0.38	GO:0003700	DNA binding transcription factor activity
0.37	GO:0004325	ferrochelatase activity
0.36	GO:0008017	microtubule binding
0.35	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.35	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.34	GO:0030554	adenyl nucleotide binding

0.43	GO:0005634	nucleus
0.42	GO:0031974	membrane-enclosed lumen
0.41	GO:0034708	methyltransferase complex
0.40	GO:0044446	intracellular organelle part
0.37	GO:0005694	chromosome
0.36	GO:0000428	DNA-directed RNA polymerase complex
0.36	GO:0005667	transcription factor complex
0.36	GO:0005794	Golgi apparatus
0.36	GO:0098588	bounding membrane of organelle
0.36	GO:0005783	endoplasmic reticulum

0.37	EC:4.99.1.1	GO:0004325
0.37	KEGG:R00310	GO:0004325

tr|T1FL75|T1FL75_HELRO
Uncharacterized protein
Search

tr|T1FL76|T1FL76_HELRO
Uncharacterized protein
Search

tr|T1FL77|T1FL77_HELRO
Uncharacterized protein
Search

tr|T1FL78|T1FL78_HELRO
Uncharacterized protein
Search

tr|T1FL79|T1FL79_HELRO
Uncharacterized protein
Search

tr|T1FL80|T1FL80_HELRO
Uncharacterized protein
Search

tr|T1FL81|T1FL81_HELRO
Uncharacterized protein
Search

tr|T1FL82|T1FL82_HELRO
Uncharacterized protein
Search

tr|T1FL83|T1FL83_HELRO
Uncharacterized protein
Search

0.43	GO:0007165	signal transduction
0.38	GO:0034220	ion transmembrane transport
0.38	GO:1903506	regulation of nucleic acid-templated transcription
0.38	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.38	GO:0010468	regulation of gene expression
0.38	GO:0006468	protein phosphorylation

0.46	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.42	GO:0005230	extracellular ligand-gated ion channel activity
0.41	GO:0030246	carbohydrate binding
0.41	GO:0004888	transmembrane signaling receptor activity
0.38	GO:0046872	metal ion binding
0.38	GO:0004672	protein kinase activity
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding

0.39	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|T1FL84|T1FL84_HELRO
Uncharacterized protein
Search

tr|T1FL85|T1FL85_HELRO
Kinase
Search

0.22

Kinase

0.82	GO:0032958	inositol phosphate biosynthetic process
0.57	GO:0016310	phosphorylation
0.44	GO:0030308	negative regulation of cell growth
0.43	GO:0043065	positive regulation of apoptotic process
0.42	GO:0046488	phosphatidylinositol metabolic process
0.42	GO:0030258	lipid modification
0.37	GO:0007227	signal transduction downstream of smoothened
0.36	GO:0045880	positive regulation of smoothened signaling pathway
0.33	GO:0006817	phosphate ion transport

0.60	GO:0016301	kinase activity
0.41	GO:0016776	phosphotransferase activity, phosphate group as acceptor

0.45	GO:0001650	fibrillar center
0.42	GO:0030054	cell junction
0.30	GO:0016020	membrane

0.41

EC:2.7.4

GO:0016776

tr|T1FL86|T1FL86_HELRO
Uncharacterized protein
Search

tr|T1FL88|T1FL88_HELRO
Uncharacterized protein
Search

tr|T1FL89|T1FL89_HELRO
Uncharacterized protein
Search

tr|T1FL90|T1FL90_HELRO
Uncharacterized protein
Search

tr|T1FL91|T1FL91_HELRO
Uncharacterized protein
Search

0.42	GO:0006357	regulation of transcription by RNA polymerase II
0.37	GO:0045893	positive regulation of transcription, DNA-templated
0.35	GO:0030042	actin filament depolymerization
0.35	GO:0036211	protein modification process
0.35	GO:0007448	anterior/posterior pattern specification, imaginal disc
0.35	GO:0044267	cellular protein metabolic process
0.35	GO:0002805	regulation of antimicrobial peptide biosynthetic process
0.35	GO:0006707	cholesterol catabolic process
0.35	GO:0046885	regulation of hormone biosynthetic process
0.34	GO:0009880	embryonic pattern specification

0.53	GO:0003677	DNA binding
0.44	GO:0001067	regulatory region nucleic acid binding
0.43	GO:0008134	transcription factor binding
0.40	GO:0003700	DNA binding transcription factor activity
0.35	GO:0004672	protein kinase activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0046872	metal ion binding
0.35	GO:0003779	actin binding
0.34	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.34	GO:0008144	drug binding

0.59	GO:0005634	nucleus
0.47	GO:0031974	membrane-enclosed lumen
0.46	GO:0005829	cytosol
0.44	GO:0005667	transcription factor complex
0.43	GO:0044446	intracellular organelle part
0.43	GO:0043232	intracellular non-membrane-bounded organelle
0.40	GO:1902494	catalytic complex
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0031224	intrinsic component of membrane

tr|T1FL92|T1FL92_HELRO
Uncharacterized protein
Search

tr|T1FL93|T1FL93_HELRO
Uncharacterized protein
Search

tr|T1FL94|T1FL94_HELRO
Uncharacterized protein
Search

PPP2R5B

0.86	Protein phosphatase 2, regulatory subunit B', beta (Fragment)

0.79	GO:0043666	regulation of phosphoprotein phosphatase activity
0.61	GO:0007165	signal transduction
0.45	GO:0008340	determination of adult lifespan
0.43	GO:0045880	positive regulation of smoothened signaling pathway
0.42	GO:1903863	P granule assembly
0.42	GO:0051225	spindle assembly
0.41	GO:0006914	autophagy
0.40	GO:0001933	negative regulation of protein phosphorylation
0.40	GO:0007059	chromosome segregation
0.39	GO:0040024	dauer larval development

0.80	GO:0019888	protein phosphatase regulator activity
0.39	GO:0019211	phosphatase activator activity
0.38	GO:0019901	protein kinase binding
0.37	GO:0004722	protein serine/threonine phosphatase activity
0.36	GO:0008270	zinc ion binding
0.35	GO:0003676	nucleic acid binding

0.81	GO:0000159	protein phosphatase type 2A complex
0.36	GO:0005634	nucleus
0.36	GO:0005829	cytosol
0.33	GO:0043233	organelle lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

tr|T1FL96|T1FL96_HELRO
Uncharacterized protein
Search

tr|T1FL97|T1FL97_HELRO
Uncharacterized protein
Search

tr|T1FL98|T1FL98_HELRO
Uncharacterized protein
Search

tr|T1FL99|T1FL99_HELRO
Uncharacterized protein
Search

tr|T1FLA0|T1FLA0_HELRO
Uncharacterized protein
Search

tr|T1FLA1|T1FLA1_HELRO
Uncharacterized protein
Search

tr|T1FLA2|T1FLA2_HELRO
Uncharacterized protein
Search

tr|T1FLA3|T1FLA3_HELRO
Uncharacterized protein
Search

tr|T1FLA4|T1FLA4_HELRO
Uncharacterized protein
Search

tr|T1FLA5|T1FLA5_HELRO
Uncharacterized protein
Search

0.60	GO:0005975	carbohydrate metabolic process
0.39	GO:1990966	ATP generation from poly-ADP-D-ribose

0.85

GO:0004649

poly(ADP-ribose) glycohydrolase activity

0.36	GO:0005654	nucleoplasm
0.36	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.85

EC:3.2.1.143

GO:0004649

tr|T1FLA6|T1FLA6_HELRO
Uncharacterized protein
Search

tr|T1FLA7|T1FLA7_HELRO
Uncharacterized protein
Search

tr|T1FLA8|T1FLA8_HELRO
Uncharacterized protein
Search

tr|T1FLA9|T1FLA9_HELRO
Uncharacterized protein
Search

tr|T1FLB0|T1FLB0_HELRO
Uncharacterized protein
Search

tr|T1FLB1|T1FLB1_HELRO
Uncharacterized protein
Search

tr|T1FLB2|T1FLB2_HELRO
Uncharacterized protein
Search

tr|T1FLB3|T1FLB3_HELRO
Uncharacterized protein
Search

0.45	GO:0048015	phosphatidylinositol-mediated signaling
0.44	GO:0046854	phosphatidylinositol phosphorylation
0.41	GO:0016192	vesicle-mediated transport
0.41	GO:0046907	intracellular transport
0.41	GO:0044267	cellular protein metabolic process
0.41	GO:0070727	cellular macromolecule localization
0.40	GO:0015031	protein transport
0.40	GO:0036211	protein modification process
0.40	GO:0045859	regulation of protein kinase activity
0.39	GO:0043039	tRNA aminoacylation

0.41	GO:0016301	kinase activity
0.41	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity
0.41	GO:0004825	methionine-tRNA ligase activity
0.39	GO:0003723	RNA binding
0.39	GO:0030554	adenyl nucleotide binding
0.39	GO:0097367	carbohydrate derivative binding
0.39	GO:0008144	drug binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0019787	ubiquitin-like protein transferase activity
0.38	GO:0019901	protein kinase binding

0.43	GO:0030117	membrane coat
0.39	GO:0044428	nuclear part
0.37	GO:0031461	cullin-RING ubiquitin ligase complex
0.37	GO:0070013	intracellular organelle lumen
0.37	GO:0005905	clathrin-coated pit
0.36	GO:0044431	Golgi apparatus part
0.35	GO:0043232	intracellular non-membrane-bounded organelle
0.35	GO:0031248	protein acetyltransferase complex
0.35	GO:1990745	EARP complex
0.35	GO:0099512	supramolecular fiber

0.41

GO:0016538

tr|T1FLB4|T1FLB4_HELRO
Uncharacterized protein
Search

tr|T1FLB5|T1FLB5_HELRO
Uncharacterized protein
Search

tr|T1FLB6|T1FLB6_HELRO
Uncharacterized protein
Search

tr|T1FLB7|T1FLB7_HELRO
Uncharacterized protein
Search

0.47	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA
0.44	GO:0043085	positive regulation of catalytic activity
0.43	GO:0006429	leucyl-tRNA aminoacylation
0.42	GO:0106074	aminoacyl-tRNA metabolism involved in translational fidelity
0.41	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.41	GO:0051171	regulation of nitrogen compound metabolic process
0.41	GO:0080090	regulation of primary metabolic process
0.40	GO:0048015	phosphatidylinositol-mediated signaling
0.39	GO:0046488	phosphatidylinositol metabolic process
0.39	GO:0046834	lipid phosphorylation

0.45	GO:0008047	enzyme activator activity
0.43	GO:0004823	leucine-tRNA ligase activity
0.43	GO:0016788	hydrolase activity, acting on ester bonds
0.42	GO:0140110	transcription regulator activity
0.38	GO:0032553	ribonucleotide binding
0.38	GO:0030554	adenyl nucleotide binding
0.38	GO:0008144	drug binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0140096	catalytic activity, acting on a protein
0.37	GO:0016772	transferase activity, transferring phosphorus-containing groups

0.37	GO:0005622	intracellular
0.36	GO:0043227	membrane-bounded organelle
0.36	GO:1990234	transferase complex
0.36	GO:0031974	membrane-enclosed lumen
0.35	GO:0043234	protein complex
0.35	GO:1990904	ribonucleoprotein complex
0.35	GO:0044422	organelle part
0.34	GO:0043228	non-membrane-bounded organelle
0.34	GO:1902555	endoribonuclease complex
0.34	GO:0017053	transcriptional repressor complex

0.43	EC:6.1.1.4	GO:0004823
0.43	KEGG:R03657	GO:0004823

tr|T1FLB8|T1FLB8_HELRO
Uncharacterized protein
Search

tr|T1FLB9|T1FLB9_HELRO
Uncharacterized protein
Search

0.48	GO:0006275	regulation of DNA replication
0.47	GO:0045893	positive regulation of transcription, DNA-templated
0.44	GO:0006260	DNA replication
0.44	GO:0043412	macromolecule modification
0.43	GO:0046907	intracellular transport
0.42	GO:0044267	cellular protein metabolic process
0.41	GO:0042254	ribosome biogenesis
0.41	GO:0016310	phosphorylation
0.41	GO:0016072	rRNA metabolic process
0.40	GO:0070727	cellular macromolecule localization

0.48	GO:0003688	DNA replication origin binding
0.43	GO:0004672	protein kinase activity
0.41	GO:0017076	purine nucleotide binding
0.41	GO:0032553	ribonucleotide binding
0.41	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0008144	drug binding
0.38	GO:0032550	purine ribonucleoside binding
0.38	GO:0003723	RNA binding
0.37	GO:0003712	transcription cofactor activity
0.37	GO:0009982	pseudouridine synthase activity

0.46	GO:0005634	nucleus
0.45	GO:0030124	AP-4 adaptor complex
0.44	GO:0030686	90S preribosome
0.44	GO:0042025	host cell nucleus
0.44	GO:0005732	small nucleolar ribonucleoprotein complex
0.43	GO:0070013	intracellular organelle lumen
0.40	GO:0044446	intracellular organelle part
0.39	GO:0043232	intracellular non-membrane-bounded organelle
0.36	GO:0020011	apicoplast
0.34	GO:0031461	cullin-RING ubiquitin ligase complex

0.37	EC:5.4.99.12	GO:0009982
0.37	KEGG:R03876	GO:0004842

tr|T1FLC0|T1FLC0_HELRO
Uncharacterized protein
Search

0.40	GO:0099120	socially cooperative development
0.38	GO:0098630	aggregation of unicellular organisms
0.38	GO:0050794	regulation of cellular process
0.38	GO:0051171	regulation of nitrogen compound metabolic process
0.38	GO:0060255	regulation of macromolecule metabolic process
0.38	GO:0080090	regulation of primary metabolic process
0.37	GO:0044248	cellular catabolic process
0.37	GO:0006907	pinocytosis
0.37	GO:0006508	proteolysis
0.37	GO:0009889	regulation of biosynthetic process

0.39	GO:0005515	protein binding
0.39	GO:0003676	nucleic acid binding
0.38	GO:0140096	catalytic activity, acting on a protein
0.38	GO:0003700	DNA binding transcription factor activity
0.37	GO:0046872	metal ion binding
0.37	GO:1901265	nucleoside phosphate binding
0.37	GO:0016787	hydrolase activity
0.36	GO:0036094	small molecule binding
0.36	GO:0098772	molecular function regulator
0.36	GO:0043168	anion binding

0.39	GO:0043227	membrane-bounded organelle
0.39	GO:0043229	intracellular organelle
0.39	GO:0012505	endomembrane system
0.37	GO:0020036	Maurer's cleft
0.37	GO:0044422	organelle part
0.37	GO:0044444	cytoplasmic part
0.37	GO:0043234	protein complex
0.36	GO:1990234	transferase complex
0.35	GO:0048475	coated membrane
0.35	GO:0098805	whole membrane

0.37	EC:3	GO:0016787
0.35	KEGG:R03083	GO:0003856

tr|T1FLC1|T1FLC1_HELRO
Uncharacterized protein
Search

tr|T1FLC2|T1FLC2_HELRO
Uncharacterized protein
Search

0.41	GO:0008643	carbohydrate transport
0.40	GO:0006352	DNA-templated transcription, initiation
0.39	GO:0065007	biological regulation
0.38	GO:0055085	transmembrane transport
0.38	GO:0016310	phosphorylation
0.38	GO:0007154	cell communication
0.38	GO:0036211	protein modification process
0.38	GO:0006368	transcription elongation from RNA polymerase II promoter
0.37	GO:0044267	cellular protein metabolic process
0.37	GO:0051716	cellular response to stimulus

0.43	GO:0046872	metal ion binding
0.40	GO:0035091	phosphatidylinositol binding
0.39	GO:0003700	DNA binding transcription factor activity
0.38	GO:0003677	DNA binding
0.38	GO:0016301	kinase activity
0.37	GO:0004435	phosphatidylinositol phospholipase C activity
0.37	GO:0046983	protein dimerization activity
0.37	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.36	GO:0008271	secondary active sulfate transmembrane transporter activity
0.36	GO:0140096	catalytic activity, acting on a protein

0.39	GO:0020011	apicoplast
0.38	GO:0005634	nucleus
0.38	GO:0045095	keratin filament
0.38	GO:0031974	membrane-enclosed lumen
0.37	GO:0000313	organellar ribosome
0.37	GO:0000428	DNA-directed RNA polymerase complex
0.35	GO:0044429	mitochondrial part
0.35	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.37	EC:3.1.4.11	GO:0004435
0.37	KEGG:R03435	GO:0004435

tr|T1FLC3|T1FLC3_HELRO
Uncharacterized protein
Search

0.68

GO:0046983

protein dimerization activity

tr|T1FLC4|T1FLC4_HELRO
Uncharacterized protein
Search

tr|T1FLC5|T1FLC5_HELRO
Uncharacterized protein
Search

tr|T1FLC6|T1FLC6_HELRO
Uncharacterized protein
Search

tr|T1FLC7|T1FLC7_HELRO
Uncharacterized protein
Search

tr|T1FLC8|T1FLC8_HELRO
Uncharacterized protein
Search

tr|T1FLC9|T1FLC9_HELRO
Uncharacterized protein
Search

0.42	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA
0.35	GO:0034428	nuclear-transcribed mRNA catabolic process, exonucleolytic, 5'-3'
0.35	GO:0031087	deadenylation-independent decapping of nuclear-transcribed mRNA
0.34	GO:0010603	regulation of cytoplasmic mRNA processing body assembly
0.34	GO:0035195	gene silencing by miRNA
0.33	GO:0006397	mRNA processing

0.72	GO:0030145	manganese ion binding
0.59	GO:0003723	RNA binding
0.51	GO:0016787	hydrolase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0000287	magnesium ion binding
0.33	GO:0005515	protein binding

0.41	GO:0000932	P-body
0.39	GO:0098745	Dcp1-Dcp2 complex
0.37	GO:0010494	cytoplasmic stress granule
0.34	GO:0005634	nucleus
0.33	GO:0005829	cytosol

0.51

GO:0016787

tr|T1FLD0|T1FLD0_HELRO
Uncharacterized protein
Search

0.47	GO:0007059	chromosome segregation
0.45	GO:0051301	cell division
0.42	GO:0065007	biological regulation
0.41	GO:0036211	protein modification process
0.40	GO:0044267	cellular protein metabolic process
0.40	GO:0071840	cellular component organization or biogenesis
0.39	GO:0043326	chemotaxis to folate
0.39	GO:0032502	developmental process
0.39	GO:0043327	chemotaxis to cAMP
0.39	GO:0016310	phosphorylation

0.49	GO:0008092	cytoskeletal protein binding
0.42	GO:0003676	nucleic acid binding
0.40	GO:0140096	catalytic activity, acting on a protein
0.40	GO:0003700	DNA binding transcription factor activity
0.39	GO:0016301	kinase activity
0.39	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.39	GO:0098772	molecular function regulator
0.39	GO:0043130	ubiquitin binding
0.39	GO:0030674	protein binding, bridging
0.38	GO:0016787	hydrolase activity

0.51	GO:0005876	spindle microtubule
0.51	GO:0000940	condensed chromosome outer kinetochore
0.43	GO:0005634	nucleus
0.39	GO:0070013	intracellular organelle lumen
0.39	GO:1990234	transferase complex
0.38	GO:0005667	transcription factor complex
0.38	GO:0005881	cytoplasmic microtubule
0.37	GO:0005815	microtubule organizing center
0.36	GO:0031362	anchored component of external side of plasma membrane
0.34	GO:0005768	endosome

0.39

GO:0016773

tr|T1FLD1|T1FLD1_HELRO
Uncharacterized protein
Search

tr|T1FLD2|T1FLD2_HELRO
Uncharacterized protein
Search

0.41

GO:0046872

metal ion binding

0.30

GO:0044425

membrane part

tr|T1FLD3|T1FLD3_HELRO
Uncharacterized protein
Search

0.48	GO:0007018	microtubule-based movement
0.38	GO:0006468	protein phosphorylation
0.38	GO:0006896	Golgi to vacuole transport
0.38	GO:0032456	endocytic recycling
0.38	GO:0007019	microtubule depolymerization
0.38	GO:0006913	nucleocytoplasmic transport
0.38	GO:0045493	xylan catabolic process
0.37	GO:0042147	retrograde transport, endosome to Golgi
0.37	GO:0000001	mitochondrion inheritance
0.37	GO:0051276	chromosome organization

0.48	GO:0003777	microtubule motor activity
0.48	GO:0008017	microtubule binding
0.43	GO:0005524	ATP binding
0.39	GO:0017056	structural constituent of nuclear pore
0.39	GO:0140096	catalytic activity, acting on a protein
0.38	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.38	GO:0019905	syntaxin binding
0.38	GO:0016301	kinase activity
0.37	GO:0017137	Rab GTPase binding
0.37	GO:0045131	pre-mRNA branch point binding

0.51	GO:0005634	nucleus
0.39	GO:0044446	intracellular organelle part
0.39	GO:0012505	endomembrane system
0.38	GO:0043234	protein complex
0.37	GO:0099023	tethering complex
0.37	GO:0031975	envelope
0.36	GO:0031410	cytoplasmic vesicle
0.36	GO:0005829	cytosol
0.36	GO:0043232	intracellular non-membrane-bounded organelle
0.35	GO:0031974	membrane-enclosed lumen

0.38

GO:0016773

tr|T1FLD4|T1FLD4_HELRO
Uncharacterized protein
Search

tr|T1FLD5|T1FLD5_HELRO
Uncharacterized protein
Search

0.47	GO:0031323	regulation of cellular metabolic process
0.47	GO:0051171	regulation of nitrogen compound metabolic process
0.47	GO:0060255	regulation of macromolecule metabolic process
0.47	GO:0080090	regulation of primary metabolic process
0.46	GO:0009889	regulation of biosynthetic process
0.40	GO:0036211	protein modification process
0.39	GO:0044267	cellular protein metabolic process
0.39	GO:0051347	positive regulation of transferase activity
0.38	GO:0043327	chemotaxis to cAMP
0.38	GO:0016310	phosphorylation

0.48	GO:0003700	DNA binding transcription factor activity
0.39	GO:0140096	catalytic activity, acting on a protein
0.39	GO:0008270	zinc ion binding
0.38	GO:0003676	nucleic acid binding
0.38	GO:0016301	kinase activity
0.38	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.38	GO:0043168	anion binding
0.38	GO:0017076	purine nucleotide binding
0.38	GO:0097367	carbohydrate derivative binding
0.37	GO:0008144	drug binding

0.43	GO:0005634	nucleus
0.41	GO:0031461	cullin-RING ubiquitin ligase complex
0.38	GO:0044446	intracellular organelle part
0.38	GO:0000331	contractile vacuole
0.37	GO:0030135	coated vesicle
0.37	GO:0012506	vesicle membrane
0.37	GO:0030117	membrane coat
0.37	GO:0005667	transcription factor complex
0.37	GO:0098805	whole membrane
0.37	GO:0098588	bounding membrane of organelle

0.38

GO:0016773

tr|T1FLD6|T1FLD6_HELRO
Uncharacterized protein
Search

0.11	Major facilitator superfamily domain-containing protein 1

0.54	GO:0055085	transmembrane transport
0.35	GO:0006260	DNA replication

0.33

GO:0003677

DNA binding

0.30

GO:0016020

membrane

tr|T1FLD7|T1FLD7_HELRO
Uncharacterized protein
Search

tr|T1FLD8|T1FLD8_HELRO
ATP-dependent DNA helicase
Search

0.10	ATP-dependent DNA helicase

0.86	GO:0044806	G-quadruplex DNA unwinding
0.86	GO:0032211	negative regulation of telomere maintenance via telomerase
0.85	GO:0051974	negative regulation of telomerase activity
0.82	GO:0000002	mitochondrial genome maintenance
0.78	GO:0000723	telomere maintenance
0.70	GO:0032508	DNA duplex unwinding
0.66	GO:0006260	DNA replication
0.65	GO:0006310	DNA recombination
0.65	GO:0006281	DNA repair

0.86	GO:0010521	telomerase inhibitor activity
0.81	GO:0043141	ATP-dependent 5'-3' DNA helicase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.74	GO:0005657	replication fork
0.61	GO:0005634	nucleus
0.61	GO:0005739	mitochondrion

0.81

EC:3.6.1

GO:0043141

tr|T1FLD9|T1FLD9_HELRO
Uncharacterized protein
Search

tr|T1FLE0|T1FLE0_HELRO
Uncharacterized protein
Search

0.41	GO:0071840	cellular component organization or biogenesis
0.39	GO:0090304	nucleic acid metabolic process
0.39	GO:0065007	biological regulation
0.39	GO:0044267	cellular protein metabolic process
0.38	GO:0007049	cell cycle
0.38	GO:0036211	protein modification process
0.38	GO:0010467	gene expression
0.37	GO:0009059	macromolecule biosynthetic process
0.36	GO:0060047	heart contraction
0.36	GO:0006936	muscle contraction

0.40	GO:0005515	protein binding
0.40	GO:0003676	nucleic acid binding
0.38	GO:0003682	chromatin binding
0.38	GO:0017076	purine nucleotide binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0032553	ribonucleotide binding
0.38	GO:0008144	drug binding
0.37	GO:0008408	3'-5' exonuclease activity
0.37	GO:0098772	molecular function regulator
0.37	GO:0008270	zinc ion binding

0.46	GO:0005634	nucleus
0.42	GO:0030684	preribosome
0.42	GO:0070013	intracellular organelle lumen
0.42	GO:0044446	intracellular organelle part
0.41	GO:0016529	sarcoplasmic reticulum
0.39	GO:0043234	protein complex
0.39	GO:0043232	intracellular non-membrane-bounded organelle
0.38	GO:0009536	plastid
0.37	GO:1990234	transferase complex
0.37	GO:0005829	cytosol

0.36

EC:3.1.13

GO:0016896

tr|T1FLE1|T1FLE1_HELRO
Uncharacterized protein
Search

tr|T1FLE2|T1FLE2_HELRO
Uncharacterized protein
Search

tr|T1FLE3|T1FLE3_HELRO
Uncharacterized protein
Search

0.49	GO:0033334	fin morphogenesis
0.48	GO:0071711	basement membrane organization
0.41	GO:0006468	protein phosphorylation

0.43	GO:0005509	calcium ion binding
0.41	GO:0004672	protein kinase activity
0.38	GO:0030554	adenyl nucleotide binding
0.38	GO:0097367	carbohydrate derivative binding
0.38	GO:0008144	drug binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0031224

intrinsic component of membrane

tr|T1FLE4|T1FLE4_HELRO
Uncharacterized protein
Search

tr|T1FLE5|T1FLE5_HELRO
Uncharacterized protein
Search

0.74

GO:0003779

actin binding

tr|T1FLE6|T1FLE6_HELRO
Uncharacterized protein
Search

tr|T1FLE7|T1FLE7_HELRO
Uncharacterized protein
Search

tr|T1FLE8|T1FLE8_HELRO
Uncharacterized protein
Search

0.50	GO:0018095	protein polyglutamylation
0.40	GO:0016180	snRNA processing
0.39	GO:0031156	regulation of sorocarp development
0.38	GO:0055085	transmembrane transport
0.37	GO:0050794	regulation of cellular process
0.37	GO:0099120	socially cooperative development
0.37	GO:0016567	protein ubiquitination
0.37	GO:0043326	chemotaxis to folate
0.37	GO:0006468	protein phosphorylation
0.37	GO:0060255	regulation of macromolecule metabolic process

0.44	GO:0030554	adenyl nucleotide binding
0.43	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0032555	purine ribonucleotide binding
0.43	GO:0008144	drug binding
0.43	GO:0043492	ATPase activity, coupled to movement of substances
0.42	GO:0015405	P-P-bond-hydrolysis-driven transmembrane transporter activity
0.38	GO:0140096	catalytic activity, acting on a protein
0.38	GO:0046872	metal ion binding
0.38	GO:0003676	nucleic acid binding
0.37	GO:0016491	oxidoreductase activity

0.42	GO:0005634	nucleus
0.39	GO:0000428	DNA-directed RNA polymerase complex
0.39	GO:0070013	intracellular organelle lumen
0.38	GO:0044446	intracellular organelle part
0.38	GO:0043234	protein complex
0.37	GO:0005856	cytoskeleton
0.36	GO:0031248	protein acetyltransferase complex
0.35	GO:0005615	extracellular space
0.35	GO:0099512	supramolecular fiber
0.35	GO:0005737	cytoplasm

0.37

GO:0016491

tr|T1FLE9|T1FLE9_HELRO
Uncharacterized protein
Search

tr|T1FLF0|T1FLF0_HELRO
Uncharacterized protein
Search

0.42	GO:0006030	chitin metabolic process
0.40	GO:0006325	chromatin organization
0.39	GO:0060255	regulation of macromolecule metabolic process
0.38	GO:0031326	regulation of cellular biosynthetic process
0.38	GO:0051171	regulation of nitrogen compound metabolic process
0.38	GO:0080090	regulation of primary metabolic process
0.38	GO:0005975	carbohydrate metabolic process
0.37	GO:0060717	chorion development
0.37	GO:0015918	sterol transport
0.37	GO:0007016	cytoskeletal anchoring at plasma membrane

0.43	GO:0008061	chitin binding
0.37	GO:0008843	endochitinase activity
0.37	GO:0032934	sterol binding
0.37	GO:0003676	nucleic acid binding
0.37	GO:0005509	calcium ion binding
0.37	GO:0004175	endopeptidase activity
0.36	GO:0003682	chromatin binding
0.36	GO:0030248	cellulose binding
0.36	GO:0042302	structural constituent of cuticle
0.36	GO:0008237	metallopeptidase activity

0.44	GO:0005576	extracellular region
0.43	GO:0005694	chromosome
0.41	GO:0005634	nucleus
0.40	GO:0044446	intracellular organelle part
0.39	GO:0070013	intracellular organelle lumen
0.38	GO:0042600	chorion
0.37	GO:0016010	dystrophin-associated glycoprotein complex
0.36	GO:0009277	fungal-type cell wall
0.36	GO:0005935	cellular bud neck
0.36	GO:0005581	collagen trimer

0.35

GO:0004674

tr|T1FLF1|T1FLF1_HELRO
Uncharacterized protein
Search

0.44	GO:0007165	signal transduction
0.39	GO:0034220	ion transmembrane transport
0.38	GO:1903506	regulation of nucleic acid-templated transcription
0.38	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.38	GO:0010468	regulation of gene expression
0.37	GO:0006468	protein phosphorylation

0.46	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.44	GO:0005230	extracellular ligand-gated ion channel activity
0.42	GO:0004888	transmembrane signaling receptor activity
0.42	GO:0030246	carbohydrate binding
0.38	GO:0046872	metal ion binding
0.37	GO:0004672	protein kinase activity
0.36	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.39	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|T1FLF2|T1FLF2_HELRO
Uncharacterized protein
Search

tr|T1FLF3|T1FLF3_HELRO
Uncharacterized protein
Search

tr|T1FLF4|T1FLF4_HELRO
Uncharacterized protein
Search

tr|T1FLF5|T1FLF5_HELRO
Uncharacterized protein
Search

tr|T1FLF6|T1FLF6_HELRO
Uncharacterized protein
Search

tr|T1FLF7|T1FLF7_HELRO
Uncharacterized protein
Search

0.49	GO:0003143	embryonic heart tube morphogenesis
0.46	GO:0070588	calcium ion transmembrane transport
0.46	GO:0015031	protein transport
0.41	GO:0010556	regulation of macromolecule biosynthetic process
0.41	GO:0031326	regulation of cellular biosynthetic process
0.41	GO:0051171	regulation of nitrogen compound metabolic process
0.41	GO:0080090	regulation of primary metabolic process
0.40	GO:0010468	regulation of gene expression
0.39	GO:0036211	protein modification process
0.39	GO:0010530	positive regulation of transposition

0.48	GO:0005245	voltage-gated calcium channel activity
0.43	GO:0003676	nucleic acid binding
0.40	GO:0140110	transcription regulator activity
0.40	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.39	GO:0140096	catalytic activity, acting on a protein
0.38	GO:0003777	microtubule motor activity
0.37	GO:0046872	metal ion binding
0.37	GO:0016301	kinase activity
0.37	GO:0030554	adenyl nucleotide binding
0.37	GO:0097367	carbohydrate derivative binding

0.48	GO:0005891	voltage-gated calcium channel complex
0.44	GO:0005634	nucleus
0.37	GO:0070013	intracellular organelle lumen
0.36	GO:0000785	chromatin
0.36	GO:0000324	fungal-type vacuole
0.36	GO:1902494	catalytic complex
0.36	GO:0005667	transcription factor complex
0.35	GO:0005829	cytosol

0.40

EC:2.4.2.30

GO:0003950

tr|T1FLF8|T1FLF8_HELRO
Uncharacterized protein
Search

0.56	GO:0006518	peptide metabolic process
0.53	GO:0055114	oxidation-reduction process

0.84	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
0.72	GO:0005507	copper ion binding
0.37	GO:0005201	extracellular matrix structural constituent
0.36	GO:0005509	calcium ion binding
0.33	GO:0003676	nucleic acid binding

0.36	GO:0005578	proteinaceous extracellular matrix
0.30	GO:0031224	intrinsic component of membrane

0.84

EC:1.14.17

GO:0016715

tr|T1FLF9|T1FLF9_HELRO
Uncharacterized protein
Search

0.55	GO:1905929	positive regulation of invadopodium disassembly
0.52	GO:0032703	negative regulation of interleukin-2 production
0.51	GO:0007026	negative regulation of microtubule depolymerization
0.51	GO:0031116	positive regulation of microtubule polymerization
0.49	GO:0030336	negative regulation of cell migration
0.35	GO:0072576	liver morphogenesis
0.34	GO:0031016	pancreas development
0.33	GO:0035335	peptidyl-tyrosine dephosphorylation
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0008017	microtubule binding
0.33	GO:0003779	actin binding
0.33	GO:0004725	protein tyrosine phosphatase activity
0.32	GO:0003700	DNA binding transcription factor activity

0.51	GO:1990752	microtubule end
0.38	GO:0005640	nuclear outer membrane
0.34	GO:0030175	filopodium
0.34	GO:0030027	lamellipodium
0.33	GO:0005794	Golgi apparatus
0.30	GO:0016021	integral component of membrane

0.33

EC:3.1.3.48

GO:0004725

tr|T1FLG0|T1FLG0_HELRO
Uncharacterized protein
Search

0.48	GO:0042254	ribosome biogenesis
0.44	GO:0016070	RNA metabolic process
0.43	GO:0010467	gene expression
0.42	GO:0006325	chromatin organization
0.42	GO:0036211	protein modification process
0.41	GO:0031323	regulation of cellular metabolic process
0.41	GO:0051171	regulation of nitrogen compound metabolic process
0.41	GO:0060255	regulation of macromolecule metabolic process
0.41	GO:0080090	regulation of primary metabolic process
0.41	GO:0034654	nucleobase-containing compound biosynthetic process

0.43	GO:0003676	nucleic acid binding
0.42	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.41	GO:0000988	transcription factor activity, protein binding
0.40	GO:0016791	phosphatase activity
0.39	GO:0140096	catalytic activity, acting on a protein
0.38	GO:1990269	RNA polymerase II C-terminal domain phosphoserine binding
0.38	GO:0003700	DNA binding transcription factor activity
0.37	GO:0004402	histone acetyltransferase activity
0.36	GO:0042393	histone binding
0.36	GO:0008270	zinc ion binding

0.53	GO:0005634	nucleus
0.44	GO:0030686	90S preribosome
0.43	GO:0005732	small nucleolar ribonucleoprotein complex
0.42	GO:0070013	intracellular organelle lumen
0.41	GO:0043232	intracellular non-membrane-bounded organelle
0.41	GO:0044446	intracellular organelle part
0.39	GO:0043234	protein complex
0.39	GO:0044444	cytoplasmic part
0.36	GO:0019898	extrinsic component of membrane
0.36	GO:0031975	envelope

0.42

GO:0003899

tr|T1FLG1|T1FLG1_HELRO
Uncharacterized protein
Search

tr|T1FLG2|T1FLG2_HELRO
Uncharacterized protein
Search

tr|T1FLG3|T1FLG3_HELRO
Uncharacterized protein
Search

tr|T1FLG4|T1FLG4_HELRO
Uncharacterized protein
Search

tr|T1FLG5|T1FLG5_HELRO
Uncharacterized protein
Search

tr|T1FLG6|T1FLG6_HELRO
Uncharacterized protein
Search

tr|T1FLG7|T1FLG7_HELRO
Uncharacterized protein
Search

tr|T1FLG8|T1FLG8_HELRO
Uncharacterized protein
Search

tr|T1FLG9|T1FLG9_HELRO
Uncharacterized protein
Search

tr|T1FLH0|T1FLH0_HELRO
Uncharacterized protein
Search

0.51	GO:0034220	ion transmembrane transport
0.44	GO:0071804	cellular potassium ion transport
0.42	GO:0034765	regulation of ion transmembrane transport
0.39	GO:0019935	cyclic-nucleotide-mediated signaling
0.38	GO:0042391	regulation of membrane potential

0.58	GO:0005216	ion channel activity
0.45	GO:0022836	gated channel activity
0.44	GO:0015079	potassium ion transmembrane transporter activity

0.41	GO:0017071	intracellular cyclic nucleotide activated cation channel complex
0.37	GO:0005887	integral component of plasma membrane
0.33	GO:0005622	intracellular

tr|T1FLH1|T1FLH1_HELRO
Uncharacterized protein
Search

tr|T1FLH2|T1FLH2_HELRO
Uncharacterized protein
Search

0.61	GO:0043484	regulation of RNA splicing
0.48	GO:0007218	neuropeptide signaling pathway
0.47	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity
0.44	GO:0009644	response to high light intensity
0.44	GO:0006396	RNA processing
0.40	GO:0016071	mRNA metabolic process
0.39	GO:1903506	regulation of nucleic acid-templated transcription
0.39	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.54	GO:0003723	RNA binding
0.49	GO:0004983	neuropeptide Y receptor activity

0.43	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|T1FLH3|T1FLH3_HELRO
Uncharacterized protein
Search

tr|T1FLH4|T1FLH4_HELRO
Uncharacterized protein
Search

tr|T1FLH5|T1FLH5_HELRO
Uncharacterized protein
Search

tr|T1FLH6|T1FLH6_HELRO
Uncharacterized protein
Search

tr|T1FLH7|T1FLH7_HELRO
Uncharacterized protein
Search

tr|T1FLH8|T1FLH8_HELRO
Uncharacterized protein
Search

tr|T1FLH9|T1FLH9_HELRO
Uncharacterized protein
Search

0.45	GO:0006355	regulation of transcription, DNA-templated
0.40	GO:0033043	regulation of organelle organization
0.40	GO:0048522	positive regulation of cellular process
0.39	GO:0018205	peptidyl-lysine modification
0.39	GO:0097230	cell motility in response to potassium ion
0.39	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.39	GO:0036051	protein localization to trailing edge
0.39	GO:0003053	circadian regulation of heart rate
0.38	GO:0061118	regulation of positive chemotaxis to cAMP
0.38	GO:0032271	regulation of protein polymerization

0.47	GO:0003700	DNA binding transcription factor activity
0.40	GO:0003676	nucleic acid binding
0.40	GO:0031386	protein tag
0.39	GO:0046983	protein dimerization activity
0.39	GO:0046872	metal ion binding
0.38	GO:0008134	transcription factor binding
0.37	GO:0004386	helicase activity
0.37	GO:0015386	potassium:proton antiporter activity
0.37	GO:0015385	sodium:proton antiporter activity
0.36	GO:0004402	histone acetyltransferase activity

0.41	GO:0005634	nucleus
0.39	GO:0030686	90S preribosome
0.38	GO:0032040	small-subunit processome
0.38	GO:0005667	transcription factor complex
0.38	GO:0070013	intracellular organelle lumen
0.38	GO:0020011	apicoplast
0.37	GO:0031256	leading edge membrane
0.36	GO:0031248	protein acetyltransferase complex
0.36	GO:0044446	intracellular organelle part
0.36	GO:0000428	DNA-directed RNA polymerase complex

0.36

GO:0004402

tr|T1FLI0|T1FLI0_HELRO
Uncharacterized protein
Search

tr|T1FLI1|T1FLI1_HELRO
Uncharacterized protein
Search

0.53	GO:0000723	telomere maintenance
0.49	GO:0032392	DNA geometric change
0.48	GO:0016567	protein ubiquitination
0.47	GO:0006310	DNA recombination
0.47	GO:0006281	DNA repair

0.56	GO:0004386	helicase activity
0.48	GO:0004842	ubiquitin-protein transferase activity
0.48	GO:0030554	adenyl nucleotide binding
0.47	GO:0008144	drug binding
0.47	GO:0032555	purine ribonucleotide binding
0.47	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0003676	nucleic acid binding
0.46	GO:0140097	catalytic activity, acting on DNA

0.48

GO:0004842

tr|T1FLI2|T1FLI2_HELRO
Uncharacterized protein
Search

tr|T1FLI3|T1FLI3_HELRO
Uncharacterized protein
Search

tr|T1FLI4|T1FLI4_HELRO
Uncharacterized protein
Search

0.45	GO:0070896	positive regulation of transposon integration
0.45	GO:0030154	cell differentiation
0.45	GO:0035282	segmentation
0.45	GO:0048731	system development
0.44	GO:0018992	germ-line sex determination
0.44	GO:0060429	epithelium development
0.44	GO:0035017	cuticle pattern formation
0.44	GO:0048067	cuticle pigmentation
0.44	GO:0008343	adult feeding behavior
0.44	GO:0048729	tissue morphogenesis

0.44	GO:0003676	nucleic acid binding
0.41	GO:0140110	transcription regulator activity
0.40	GO:0140096	catalytic activity, acting on a protein
0.40	GO:0046872	metal ion binding
0.39	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.39	GO:0046983	protein dimerization activity
0.39	GO:0016301	kinase activity
0.39	GO:0016278	lysine N-methyltransferase activity
0.38	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.38	GO:0030248	cellulose binding

0.45	GO:0005634	nucleus
0.43	GO:0070013	intracellular organelle lumen
0.41	GO:0005576	extracellular region
0.41	GO:1990234	transferase complex
0.40	GO:0044446	intracellular organelle part
0.39	GO:0005667	transcription factor complex
0.38	GO:1905368	peptidase complex
0.37	GO:0005794	Golgi apparatus
0.37	GO:0005700	polytene chromosome
0.35	GO:0098588	bounding membrane of organelle

0.39

GO:0016773

tr|T1FLI5|T1FLI5_HELRO
Uncharacterized protein
Search

tr|T1FLI6|T1FLI6_HELRO
Uncharacterized protein
Search

tr|T1FLI7|T1FLI7_HELRO
Uncharacterized protein
Search

tr|T1FLI8|T1FLI8_HELRO
Uncharacterized protein
Search

tr|T1FLI9|T1FLI9_HELRO
Uncharacterized protein
Search

tr|T1FLJ0|T1FLJ0_HELRO
Uncharacterized protein
Search

tr|T1FLJ1|T1FLJ1_HELRO
Uncharacterized protein
Search

tr|T1FLJ2|T1FLJ2_HELRO
Uncharacterized protein
Search

tr|T1FLJ3|T1FLJ3_HELRO
Uncharacterized protein
Search

tr|T1FLJ4|T1FLJ4_HELRO
Uncharacterized protein
Search

tr|T1FLJ5|T1FLJ5_HELRO
Uncharacterized protein
Search

tr|T1FLJ6|T1FLJ6_HELRO
Uncharacterized protein
Search

0.80	GO:0006654	phosphatidic acid biosynthetic process
0.79	GO:0048017	inositol lipid-mediated signaling
0.68	GO:0016042	lipid catabolic process
0.52	GO:0048214	regulation of Golgi vesicle fusion to target membrane
0.50	GO:0001703	gastrulation with mouth forming first
0.49	GO:0031340	positive regulation of vesicle fusion
0.49	GO:0007349	cellularization
0.47	GO:0007030	Golgi organization
0.46	GO:0007602	phototransduction
0.39	GO:0019375	galactolipid biosynthetic process

0.82	GO:0004630	phospholipase D activity
0.76	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity
0.71	GO:0035091	phosphatidylinositol binding
0.32	GO:0016491	oxidoreductase activity

0.45	GO:0005622	intracellular
0.44	GO:0031982	vesicle
0.36	GO:0012505	endomembrane system
0.34	GO:0005628	prospore membrane
0.30	GO:0016021	integral component of membrane

0.82

EC:3.1.4.4

GO:0004630

tr|T1FLJ7|T1FLJ7_HELRO
Uncharacterized protein
Search

tr|T1FLJ8|T1FLJ8_HELRO
Uncharacterized protein
Search

tr|T1FLJ9|T1FLJ9_HELRO
Uncharacterized protein
Search

tr|T1FLK0|T1FLK0_HELRO
Uncharacterized protein
Search

tr|T1FLK1|T1FLK1_HELRO
Uncharacterized protein
Search

tr|T1FLK2|T1FLK2_HELRO
Uncharacterized protein
Search

tr|T1FLK3|T1FLK3_HELRO
Uncharacterized protein
Search

tr|T1FLK4|T1FLK4_HELRO
Uncharacterized protein
Search

tr|T1FLK5|T1FLK5_HELRO
Uncharacterized protein
Search

tr|T1FLK6|T1FLK6_HELRO
Uncharacterized protein
Search

tr|T1FLK7|T1FLK7_HELRO
Uncharacterized protein
Search

0.81	Parkin coregulated gene protein (Fragment)

0.77	GO:0007286	spermatid development
0.73	GO:0060548	negative regulation of cell death
0.46	GO:0034620	cellular response to unfolded protein
0.34	GO:0043043	peptide biosynthetic process
0.33	GO:0044267	cellular protein metabolic process
0.33	GO:0010467	gene expression
0.33	GO:0009059	macromolecule biosynthetic process

0.81	GO:0051879	Hsp90 protein binding
0.81	GO:0030544	Hsp70 protein binding
0.81	GO:0043014	alpha-tubulin binding
0.78	GO:0048487	beta-tubulin binding
0.75	GO:0031625	ubiquitin protein ligase binding
0.75	GO:0001664	G-protein coupled receptor binding
0.72	GO:0051087	chaperone binding
0.69	GO:0003779	actin binding
0.34	GO:0003735	structural constituent of ribosome

0.82	GO:0097225	sperm midpiece
0.75	GO:0044297	cell body
0.73	GO:0043005	neuron projection
0.68	GO:0031982	vesicle
0.65	GO:0005829	cytosol
0.57	GO:0005739	mitochondrion
0.37	GO:0005634	nucleus
0.34	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

tr|T1FLK8|T1FLK8_HELRO
Uncharacterized protein
Search

tr|T1FLK9|T1FLK9_HELRO
Uncharacterized protein
Search

tr|T1FLL0|T1FLL0_HELRO
Uncharacterized protein
Search

0.51	GO:0006888	ER to Golgi vesicle-mediated transport
0.47	GO:0006886	intracellular protein transport
0.44	GO:0036211	protein modification process
0.43	GO:0044267	cellular protein metabolic process
0.41	GO:0016310	phosphorylation
0.38	GO:0010467	gene expression
0.37	GO:0030100	regulation of endocytosis
0.37	GO:0060255	regulation of macromolecule metabolic process
0.37	GO:0016071	mRNA metabolic process
0.37	GO:0043043	peptide biosynthetic process

0.46	GO:0008270	zinc ion binding
0.44	GO:0140096	catalytic activity, acting on a protein
0.43	GO:0032559	adenyl ribonucleotide binding
0.43	GO:0016301	kinase activity
0.42	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.42	GO:0008144	drug binding
0.42	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0003676	nucleic acid binding
0.38	GO:0030248	cellulose binding
0.37	GO:0003735	structural constituent of ribosome

0.51	GO:0030127	COPII vesicle coat
0.40	GO:0005761	mitochondrial ribosome
0.39	GO:0005634	nucleus
0.37	GO:0005667	transcription factor complex
0.37	GO:0020011	apicoplast
0.37	GO:0005845	mRNA cap binding complex
0.36	GO:0120114	Sm-like protein family complex
0.36	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.42

GO:0016773

tr|T1FLL1|T1FLL1_HELRO
Uncharacterized protein
Search

0.84	GO:0042073	intraciliary transport
0.79	GO:0060271	cilium assembly
0.55	GO:0003334	keratinocyte development
0.55	GO:0033630	positive regulation of cell adhesion mediated by integrin
0.53	GO:0050680	negative regulation of epithelial cell proliferation
0.53	GO:0007368	determination of left/right symmetry
0.52	GO:0007219	Notch signaling pathway
0.51	GO:0007507	heart development
0.49	GO:0045944	positive regulation of transcription by RNA polymerase II
0.44	GO:0035776	pronephric proximal tubule development

0.84	GO:0048487	beta-tubulin binding
0.50	GO:0003682	chromatin binding
0.35	GO:0140034	methylation-dependent protein binding
0.35	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.35	GO:0042393	histone binding
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0097367	carbohydrate derivative binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.84	GO:0030992	intraciliary transport particle B
0.76	GO:0005929	cilium
0.52	GO:0005813	centrosome
0.43	GO:0005634	nucleus
0.34	GO:0031410	cytoplasmic vesicle
0.34	GO:0005887	integral component of plasma membrane

0.35

EC:2.7.10.1

GO:0004714

tr|T1FLL2|T1FLL2_HELRO
Uncharacterized protein
Search

tr|T1FLL3|T1FLL3_HELRO
Uncharacterized protein
Search

tr|T1FLL5|T1FLL5_HELRO
Uncharacterized protein
Search

tr|T1FLL6|T1FLL6_HELRO
Uncharacterized protein
Search

0.10	LPXTG cell wall surface protein

0.44	GO:0007155	cell adhesion
0.40	GO:0006030	chitin metabolic process
0.39	GO:0000272	polysaccharide catabolic process
0.37	GO:0006508	proteolysis
0.36	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.36	GO:0006955	immune response
0.36	GO:0006898	receptor-mediated endocytosis
0.36	GO:1902476	chloride transmembrane transport
0.36	GO:0035335	peptidyl-tyrosine dephosphorylation
0.35	GO:0010951	negative regulation of endopeptidase activity

0.46	GO:0008061	chitin binding
0.39	GO:0008234	cysteine-type peptidase activity
0.39	GO:0005518	collagen binding
0.38	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.38	GO:0030246	carbohydrate binding
0.37	GO:0005044	scavenger receptor activity
0.37	GO:0015377	cation:chloride symporter activity
0.37	GO:0001871	pattern binding
0.36	GO:0004867	serine-type endopeptidase inhibitor activity
0.36	GO:0004725	protein tyrosine phosphatase activity

0.42	GO:0005576	extracellular region
0.36	GO:0005618	cell wall
0.36	GO:0005581	collagen trimer
0.35	GO:0031226	intrinsic component of plasma membrane
0.33	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.39

GO:0008234

tr|T1FLL8|T1FLL8_HELRO
Uncharacterized protein
Search

tr|T1FLL9|T1FLL9_HELRO
Uncharacterized protein
Search

tr|T1FLM0|T1FLM0_HELRO
Uncharacterized protein
Search

0.46	GO:1903506	regulation of nucleic acid-templated transcription
0.46	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.46	GO:0010468	regulation of gene expression
0.40	GO:0006914	autophagy
0.40	GO:0099139	cheating during chimeric sorocarp development
0.39	GO:1990126	retrograde transport, endosome to plasma membrane
0.39	GO:0045022	early endosome to late endosome transport
0.38	GO:0043412	macromolecule modification
0.38	GO:0006369	termination of RNA polymerase II transcription
0.38	GO:0010501	RNA secondary structure unwinding

0.49	GO:0003700	DNA binding transcription factor activity
0.40	GO:0019899	enzyme binding
0.40	GO:0003676	nucleic acid binding
0.40	GO:0008641	ubiquitin-like modifier activating enzyme activity
0.39	GO:0032559	adenyl ribonucleotide binding
0.39	GO:0042623	ATPase activity, coupled
0.39	GO:0008144	drug binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0004674	protein serine/threonine kinase activity
0.38	GO:0001099	basal RNA polymerase II transcription machinery binding

0.42	GO:0005634	nucleus
0.40	GO:0015629	actin cytoskeleton
0.39	GO:0097422	tubular endosome
0.39	GO:0044430	cytoskeletal part
0.38	GO:0043234	protein complex
0.38	GO:0043233	organelle lumen
0.38	GO:0005770	late endosome
0.38	GO:0005769	early endosome
0.37	GO:0030133	transport vesicle
0.37	GO:0015630	microtubule cytoskeleton

0.38	EC:2.7.11	GO:0004674
0.37	KEGG:R01801	GO:0008444

tr|T1FLM1|T1FLM1_HELRO
Uncharacterized protein
Search

0.44	GO:0065007	biological regulation
0.44	GO:0008340	determination of adult lifespan
0.42	GO:1903047	mitotic cell cycle process
0.41	GO:0032189	maintenance of actomyosin contractile ring localization
0.41	GO:0036211	protein modification process
0.41	GO:0006979	response to oxidative stress
0.40	GO:0044267	cellular protein metabolic process
0.40	GO:0006505	GPI anchor metabolic process
0.39	GO:0006661	phosphatidylinositol biosynthetic process
0.39	GO:0042158	lipoprotein biosynthetic process

0.42	GO:0003700	DNA binding transcription factor activity
0.41	GO:0003676	nucleic acid binding
0.40	GO:0008691	3-hydroxybutyryl-CoA dehydrogenase activity
0.39	GO:0004672	protein kinase activity
0.38	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity
0.38	GO:0003964	RNA-directed DNA polymerase activity
0.38	GO:0097367	carbohydrate derivative binding
0.38	GO:0008144	drug binding
0.37	GO:0004842	ubiquitin-protein transferase activity
0.37	GO:0030554	adenyl nucleotide binding

0.47	GO:0005634	nucleus
0.43	GO:0000791	euchromatin
0.43	GO:0005700	polytene chromosome
0.41	GO:0034708	methyltransferase complex
0.40	GO:0042765	GPI-anchor transamidase complex
0.40	GO:0005576	extracellular region
0.40	GO:0048476	Holliday junction resolvase complex
0.39	GO:0031974	membrane-enclosed lumen
0.36	GO:0005886	plasma membrane

0.40	EC:1.1.1.157	GO:0008691
0.37	KEGG:R03876	GO:0004842

tr|T1FLM2|T1FLM2_HELRO
Uncharacterized protein
Search

0.42	GO:0036211	protein modification process
0.40	GO:0044267	cellular protein metabolic process
0.38	GO:0060255	regulation of macromolecule metabolic process
0.38	GO:0016569	covalent chromatin modification
0.38	GO:0031323	regulation of cellular metabolic process
0.38	GO:0051171	regulation of nitrogen compound metabolic process
0.38	GO:0080090	regulation of primary metabolic process
0.37	GO:0009889	regulation of biosynthetic process
0.37	GO:0016310	phosphorylation
0.37	GO:0006886	intracellular protein transport

0.40	GO:0140096	catalytic activity, acting on a protein
0.38	GO:0016740	transferase activity
0.37	GO:0035091	phosphatidylinositol binding
0.37	GO:0140110	transcription regulator activity
0.37	GO:0097367	carbohydrate derivative binding
0.37	GO:0008144	drug binding
0.37	GO:0030554	adenyl nucleotide binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0003676	nucleic acid binding
0.35	GO:0008270	zinc ion binding

0.38	GO:0005634	nucleus
0.35	GO:0016281	eukaryotic translation initiation factor 4F complex
0.34	GO:0000932	P-body
0.34	GO:0010494	cytoplasmic stress granule
0.34	GO:0098588	bounding membrane of organelle
0.34	GO:0031984	organelle subcompartment
0.34	GO:0012505	endomembrane system
0.33	GO:0042555	MCM complex
0.33	GO:0020011	apicoplast
0.33	GO:0005856	cytoskeleton

0.38

GO:0016740

tr|T1FLM3|T1FLM3_HELRO
Uncharacterized protein
Search

tr|T1FLM4|T1FLM4_HELRO
Uncharacterized protein
Search

tr|T1FLM5|T1FLM5_HELRO
Uncharacterized protein
Search

tr|T1FLM6|T1FLM6_HELRO
Uncharacterized protein
Search

tr|T1FLM7|T1FLM7_HELRO
Uncharacterized protein
Search

tr|T1FLM8|T1FLM8_HELRO
Uncharacterized protein
Search

tr|T1FLM9|T1FLM9_HELRO
Uncharacterized protein
Search

tr|T1FLN0|T1FLN0_HELRO
Uncharacterized protein
Search

tr|T1FLN1|T1FLN1_HELRO
Uncharacterized protein
Search

0.44	GO:0044419	interspecies interaction between organisms
0.43	GO:0050808	synapse organization
0.42	GO:0019226	transmission of nerve impulse
0.42	GO:0042552	myelination
0.42	GO:0007422	peripheral nervous system development
0.42	GO:0048869	cellular developmental process
0.41	GO:0007155	cell adhesion
0.41	GO:0002175	protein localization to paranode region of axon
0.41	GO:0071205	protein localization to juxtaparanode region of axon
0.40	GO:0120036	plasma membrane bounded cell projection organization

0.42	GO:0086080	protein binding involved in heterotypic cell-cell adhesion
0.40	GO:0140096	catalytic activity, acting on a protein
0.38	GO:0019904	protein domain specific binding
0.38	GO:0030248	cellulose binding
0.38	GO:0005199	structural constituent of cell wall
0.37	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.37	GO:0017171	serine hydrolase activity
0.37	GO:0016301	kinase activity
0.37	GO:0046966	thyroid hormone receptor binding
0.37	GO:0051879	Hsp90 protein binding

0.43	GO:0036338	viral membrane
0.41	GO:0044428	nuclear part
0.41	GO:0033010	paranodal junction
0.41	GO:0005576	extracellular region
0.41	GO:0043194	axon initial segment
0.41	GO:0033270	paranode region of axon
0.40	GO:0043209	myelin sheath
0.39	GO:0032991	macromolecular complex
0.39	GO:0097454	Schwann cell microvillus
0.38	GO:0005618	cell wall

0.37

GO:0016773

tr|T1FLN2|T1FLN2_HELRO
Uncharacterized protein
Search

tr|T1FLN3|T1FLN3_HELRO
Uncharacterized protein
Search

tr|T1FLN4|T1FLN4_HELRO
Uncharacterized protein
Search

tr|T1FLN5|T1FLN5_HELRO
Uncharacterized protein
Search

tr|T1FLN6|T1FLN6_HELRO
Uncharacterized protein
Search

tr|T1FLN7|T1FLN7_HELRO
Uncharacterized protein
Search

tr|T1FLN8|T1FLN8_HELRO
Uncharacterized protein
Search

0.49	GO:0007186	G-protein coupled receptor signaling pathway
0.48	GO:0016567	protein ubiquitination
0.45	GO:0007633	pattern orientation
0.43	GO:0035220	wing disc development
0.43	GO:0007560	imaginal disc morphogenesis
0.43	GO:0007626	locomotory behavior
0.42	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway
0.42	GO:0035120	post-embryonic appendage morphogenesis
0.42	GO:0035114	imaginal disc-derived appendage morphogenesis
0.41	GO:0030534	adult behavior

0.51	GO:0008528	G-protein coupled peptide receptor activity
0.49	GO:0004842	ubiquitin-protein transferase activity
0.39	GO:0018024	histone-lysine N-methyltransferase activity
0.39	GO:0016772	transferase activity, transferring phosphorus-containing groups
0.38	GO:0043168	anion binding
0.38	GO:0030554	adenyl nucleotide binding
0.38	GO:0008144	drug binding
0.38	GO:0003676	nucleic acid binding
0.38	GO:0097367	carbohydrate derivative binding
0.38	GO:0070491	repressing transcription factor binding

0.44	GO:0005634	nucleus
0.37	GO:0005694	chromosome
0.36	GO:0005667	transcription factor complex
0.36	GO:0005737	cytoplasm
0.35	GO:0031932	TORC2 complex
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0071944	cell periphery
0.30	GO:0016020	membrane

0.39	EC:2.1.1.43	GO:0018024
0.49	KEGG:R03876	GO:0004842

tr|T1FLN9|T1FLN9_HELRO
Uncharacterized protein
Search

0.43	GO:2001141	regulation of RNA biosynthetic process
0.43	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.43	GO:0010468	regulation of gene expression
0.35	GO:0031288	sorocarp morphogenesis
0.35	GO:0031152	aggregation involved in sorocarp development
0.35	GO:0032259	methylation
0.34	GO:0045773	positive regulation of axon extension
0.34	GO:0016192	vesicle-mediated transport
0.34	GO:0007411	axon guidance
0.34	GO:0051260	protein homooligomerization

0.49	GO:0003677	DNA binding
0.37	GO:0017076	purine nucleotide binding
0.37	GO:0097367	carbohydrate derivative binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0008144	drug binding
0.35	GO:0008168	methyltransferase activity
0.35	GO:0003723	RNA binding
0.34	GO:0017111	nucleoside-triphosphatase activity
0.34	GO:0004693	cyclin-dependent protein serine/threonine kinase activity
0.34	GO:0015405	P-P-bond-hydrolysis-driven transmembrane transporter activity

0.54	GO:0005634	nucleus
0.34	GO:0000932	P-body
0.34	GO:0000178	exosome (RNase complex)
0.34	GO:0098796	membrane protein complex
0.33	GO:0048475	coated membrane
0.33	GO:0098533	ATPase dependent transmembrane transport complex
0.33	GO:0005829	cytosol
0.33	GO:0044459	plasma membrane part
0.33	GO:0070013	intracellular organelle lumen
0.32	GO:0044446	intracellular organelle part

0.35	EC:2.1.1	GO:0008168
0.34	KEGG:R00130	GO:0004140

tr|T1FLP0|T1FLP0_HELRO
Uncharacterized protein
Search

tr|T1FLP1|T1FLP1_HELRO
Uncharacterized protein
Search

tr|T1FLP2|T1FLP2_HELRO
Uncharacterized protein
Search

tr|T1FLP3|T1FLP3_HELRO
Uncharacterized protein
Search

tr|T1FLP4|T1FLP4_HELRO
Uncharacterized protein
Search

tr|T1FLP5|T1FLP5_HELRO
Uncharacterized protein
Search

tr|T1FLP6|T1FLP6_HELRO
Uncharacterized protein
Search

tr|T1FLP7|T1FLP7_HELRO
Uncharacterized protein
Search

tr|T1FLP8|T1FLP8_HELRO
Uncharacterized protein
Search

0.81	Parkin coregulated gene protein (Fragment)

0.77	GO:0007286	spermatid development
0.73	GO:0060548	negative regulation of cell death
0.46	GO:0034620	cellular response to unfolded protein
0.34	GO:0043043	peptide biosynthetic process
0.33	GO:0044267	cellular protein metabolic process
0.33	GO:0010467	gene expression
0.33	GO:0009059	macromolecule biosynthetic process

0.81	GO:0051879	Hsp90 protein binding
0.81	GO:0030544	Hsp70 protein binding
0.81	GO:0043014	alpha-tubulin binding
0.78	GO:0048487	beta-tubulin binding
0.75	GO:0031625	ubiquitin protein ligase binding
0.75	GO:0001664	G-protein coupled receptor binding
0.72	GO:0051087	chaperone binding
0.69	GO:0003779	actin binding
0.34	GO:0003735	structural constituent of ribosome

0.82	GO:0097225	sperm midpiece
0.75	GO:0044297	cell body
0.73	GO:0043005	neuron projection
0.68	GO:0031982	vesicle
0.65	GO:0005829	cytosol
0.57	GO:0005739	mitochondrion
0.37	GO:0005634	nucleus
0.34	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

tr|T1FLP9|T1FLP9_HELRO
Uncharacterized protein
Search

tr|T1FLQ0|T1FLQ0_HELRO
Uncharacterized protein
Search

0.74

GO:0007018

microtubule-based movement

0.74	GO:0003777	microtubule motor activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

tr|T1FLQ1|T1FLQ1_HELRO
Uncharacterized protein
Search

0.50

GO:0035335

peptidyl-tyrosine dephosphorylation

0.50

GO:0004725

protein tyrosine phosphatase activity

0.30

GO:0031224

intrinsic component of membrane

0.50

EC:3.1.3.48

GO:0004725

tr|T1FLQ2|T1FLQ2_HELRO
Uncharacterized protein
Search

tr|T1FLQ3|T1FLQ3_HELRO
Uncharacterized protein
Search

tr|T1FLQ4|T1FLQ4_HELRO
Uncharacterized protein
Search

tr|T1FLQ5|T1FLQ5_HELRO
Uncharacterized protein
Search

0.30

GO:0044425

membrane part

tr|T1FLQ6|T1FLQ6_HELRO
Uncharacterized protein
Search

0.54	GO:0000723	telomere maintenance
0.50	GO:0032392	DNA geometric change
0.48	GO:0006310	DNA recombination
0.47	GO:0006470	protein dephosphorylation
0.47	GO:0006281	DNA repair
0.46	GO:0016567	protein ubiquitination

0.52	GO:0004386	helicase activity
0.48	GO:0004721	phosphoprotein phosphatase activity
0.47	GO:0004842	ubiquitin-protein transferase activity
0.46	GO:0140097	catalytic activity, acting on DNA
0.45	GO:0032559	adenyl ribonucleotide binding
0.44	GO:0008144	drug binding
0.44	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0003676	nucleic acid binding

0.30

GO:0016020

membrane

0.48	EC:3.1.3.16	GO:0004721
0.47	KEGG:R03876	GO:0004842

tr|T1FLQ7|T1FLQ7_HELRO
Uncharacterized protein
Search

tr|T1FLQ8|T1FLQ8_HELRO
Uncharacterized protein
Search

tr|T1FLQ9|T1FLQ9_HELRO
Uncharacterized protein
Search

tr|T1FLR0|T1FLR0_HELRO
Uncharacterized protein
Search

tr|T1FLR1|T1FLR1_HELRO
Uncharacterized protein
Search

tr|T1FLR2|T1FLR2_HELRO
Uncharacterized protein
Search

tr|T1FLR3|T1FLR3_HELRO
Uncharacterized protein
Search

0.43	GO:0036211	protein modification process
0.42	GO:0044267	cellular protein metabolic process
0.39	GO:0006325	chromatin organization
0.39	GO:0050794	regulation of cellular process
0.38	GO:0051171	regulation of nitrogen compound metabolic process
0.38	GO:0060255	regulation of macromolecule metabolic process
0.38	GO:0080090	regulation of primary metabolic process
0.38	GO:0048518	positive regulation of biological process
0.37	GO:0009889	regulation of biosynthetic process
0.37	GO:0065009	regulation of molecular function

0.42	GO:0030554	adenyl nucleotide binding
0.41	GO:0008144	drug binding
0.41	GO:0032555	purine ribonucleotide binding
0.41	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0004842	ubiquitin-protein transferase activity
0.39	GO:0004402	histone acetyltransferase activity
0.39	GO:0003676	nucleic acid binding
0.38	GO:0004672	protein kinase activity
0.38	GO:0046872	metal ion binding
0.38	GO:0016874	ligase activity

0.40	GO:0005634	nucleus
0.36	GO:1990234	transferase complex
0.36	GO:0070013	intracellular organelle lumen
0.36	GO:0020011	apicoplast
0.35	GO:0005918	septate junction
0.35	GO:0034045	phagophore assembly site membrane
0.35	GO:0005667	transcription factor complex
0.35	GO:0045177	apical part of cell
0.34	GO:0044446	intracellular organelle part
0.34	GO:0043005	neuron projection

0.39	EC:2.3.1.48	GO:0004402
0.41	KEGG:R03876	GO:0004842

tr|T1FLR4|T1FLR4_HELRO
Uncharacterized protein
Search

0.45	GO:0060255	regulation of macromolecule metabolic process
0.44	GO:0031323	regulation of cellular metabolic process
0.44	GO:0051171	regulation of nitrogen compound metabolic process
0.44	GO:0080090	regulation of primary metabolic process
0.44	GO:0009889	regulation of biosynthetic process
0.41	GO:0099120	socially cooperative development
0.40	GO:0098630	aggregation of unicellular organisms
0.40	GO:0031285	regulation of sorocarp stalk cell differentiation
0.40	GO:0016043	cellular component organization
0.39	GO:0065009	regulation of molecular function

0.45	GO:0140110	transcription regulator activity
0.40	GO:0005515	protein binding
0.39	GO:0003676	nucleic acid binding
0.39	GO:0098772	molecular function regulator
0.38	GO:0030554	adenyl nucleotide binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0032555	purine ribonucleotide binding
0.38	GO:0008144	drug binding
0.38	GO:0046872	metal ion binding
0.38	GO:0140096	catalytic activity, acting on a protein

0.43	GO:0005634	nucleus
0.38	GO:0044446	intracellular organelle part
0.38	GO:0001931	uropod
0.37	GO:0070013	intracellular organelle lumen
0.37	GO:0005768	endosome
0.37	GO:0043234	protein complex
0.37	GO:0000428	DNA-directed RNA polymerase complex
0.37	GO:0031257	cell trailing edge membrane
0.37	GO:0005856	cytoskeleton
0.36	GO:0005829	cytosol

0.37	EC:3.6.4.4	GO:0008574
0.35	KEGG:R08715	GO:0052761

tr|T1FLR5|T1FLR5_HELRO
Uncharacterized protein
Search

0.42	GO:0060255	regulation of macromolecule metabolic process
0.42	GO:0009889	regulation of biosynthetic process
0.42	GO:0031323	regulation of cellular metabolic process
0.42	GO:0051171	regulation of nitrogen compound metabolic process
0.42	GO:0080090	regulation of primary metabolic process
0.39	GO:0099120	socially cooperative development
0.38	GO:0043412	macromolecule modification
0.38	GO:0043085	positive regulation of catalytic activity
0.38	GO:0044265	cellular macromolecule catabolic process
0.38	GO:0019538	protein metabolic process

0.42	GO:0003700	DNA binding transcription factor activity
0.39	GO:0046872	metal ion binding
0.39	GO:0003676	nucleic acid binding
0.38	GO:0008047	enzyme activator activity
0.38	GO:0005515	protein binding
0.38	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.37	GO:1901265	nucleoside phosphate binding
0.37	GO:0097367	carbohydrate derivative binding
0.37	GO:0030695	GTPase regulator activity
0.37	GO:0016772	transferase activity, transferring phosphorus-containing groups

0.42	GO:0005634	nucleus
0.36	GO:0070013	intracellular organelle lumen
0.36	GO:0044446	intracellular organelle part
0.36	GO:0048786	presynaptic active zone
0.36	GO:0032991	macromolecular complex
0.36	GO:0031301	integral component of organelle membrane
0.35	GO:0098588	bounding membrane of organelle
0.35	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.35	GO:0043232	intracellular non-membrane-bounded organelle
0.35	GO:0030134	COPII-coated ER to Golgi transport vesicle

0.38

GO:0036459

tr|T1FLR6|T1FLR6_HELRO
Uncharacterized protein
Search

tr|T1FLR7|T1FLR7_HELRO
Uncharacterized protein
Search

tr|T1FLR8|T1FLR8_HELRO
Uncharacterized protein
Search

tr|T1FLR9|T1FLR9_HELRO
Uncharacterized protein
Search

tr|T1FLS0|T1FLS0_HELRO
Uncharacterized protein
Search

tr|T1FLS1|T1FLS1_HELRO
Uncharacterized protein
Search

0.42	GO:0036211	protein modification process
0.40	GO:0044267	cellular protein metabolic process
0.39	GO:0016310	phosphorylation
0.38	GO:0007017	microtubule-based process
0.38	GO:0006928	movement of cell or subcellular component
0.38	GO:0065007	biological regulation
0.38	GO:0048869	cellular developmental process
0.37	GO:0006996	organelle organization
0.37	GO:0006950	response to stress
0.37	GO:0090304	nucleic acid metabolic process

0.41	GO:0004672	protein kinase activity
0.41	GO:0030554	adenyl nucleotide binding
0.40	GO:0097367	carbohydrate derivative binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0008144	drug binding
0.38	GO:0003777	microtubule motor activity
0.38	GO:0005515	protein binding
0.38	GO:0140110	transcription regulator activity
0.38	GO:0043565	sequence-specific DNA binding
0.37	GO:0044212	transcription regulatory region DNA binding

0.41	GO:0005634	nucleus
0.39	GO:0030286	dynein complex
0.38	GO:1990234	transferase complex
0.37	GO:0070013	intracellular organelle lumen
0.36	GO:0005667	transcription factor complex
0.35	GO:0005938	cell cortex
0.35	GO:0020011	apicoplast
0.34	GO:0005663	DNA replication factor C complex
0.34	GO:0043235	receptor complex
0.34	GO:0000922	spindle pole

0.37	EC:3.6.1.3	GO:0016887
0.37	KEGG:R03876	GO:0004842

tr|T1FLS2|T1FLS2_HELRO
Uncharacterized protein
Search

tr|T1FLS3|T1FLS3_HELRO
Uncharacterized protein
Search

tr|T1FLS4|T1FLS4_HELRO
Uncharacterized protein
Search

0.50

GO:0007186

G-protein coupled receptor signaling pathway

0.51

GO:0004930

G-protein coupled receptor activity

0.30

GO:0044425

membrane part

tr|T1FLS5|T1FLS5_HELRO
Uncharacterized protein
Search

tr|T1FLS6|T1FLS6_HELRO
Uncharacterized protein
Search

0.53	GO:0006511	ubiquitin-dependent protein catabolic process
0.41	GO:1903506	regulation of nucleic acid-templated transcription
0.41	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.41	GO:0010468	regulation of gene expression
0.39	GO:0051568	histone H3-K4 methylation
0.39	GO:0007093	mitotic cell cycle checkpoint
0.39	GO:0051304	chromosome separation
0.39	GO:0043248	proteasome assembly
0.38	GO:0010498	proteasomal protein catabolic process
0.38	GO:0016567	protein ubiquitination

0.42	GO:0003700	DNA binding transcription factor activity
0.41	GO:0035299	inositol pentakisphosphate 2-kinase activity
0.40	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.39	GO:0031593	polyubiquitin modification-dependent protein binding
0.39	GO:0004712	protein serine/threonine/tyrosine kinase activity
0.39	GO:0016639	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
0.39	GO:0003676	nucleic acid binding
0.38	GO:0032559	adenyl ribonucleotide binding
0.38	GO:0005230	extracellular ligand-gated ion channel activity
0.38	GO:0004842	ubiquitin-protein transferase activity

0.59	GO:0008540	proteasome regulatory particle, base subcomplex
0.42	GO:0005634	nucleus
0.39	GO:0034708	methyltransferase complex
0.37	GO:0043233	organelle lumen
0.37	GO:0005829	cytosol
0.35	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.41	EC:2.7.1.158	GO:0035299
0.41	KEGG:R05202	GO:0035299

tr|T1FLS7|T1FLS7_HELRO
Uncharacterized protein
Search

0.41

GO:0046872

metal ion binding

0.30

GO:0044425

membrane part

tr|T1FLS8|T1FLS8_HELRO
Uncharacterized protein
Search

tr|T1FLS9|T1FLS9_HELRO
Uncharacterized protein
Search

tr|T1FLT0|T1FLT0_HELRO
Uncharacterized protein
Search

tr|T1FLT1|T1FLT1_HELRO
Uncharacterized protein
Search

tr|T1FLT2|T1FLT2_HELRO
Uncharacterized protein
Search

tr|T1FLT3|T1FLT3_HELRO
Uncharacterized protein
Search

0.45	GO:0070727	cellular macromolecule localization
0.45	GO:0046907	intracellular transport
0.44	GO:0060255	regulation of macromolecule metabolic process
0.44	GO:0031323	regulation of cellular metabolic process
0.44	GO:0051171	regulation of nitrogen compound metabolic process
0.44	GO:0080090	regulation of primary metabolic process
0.44	GO:0008104	protein localization
0.44	GO:0009889	regulation of biosynthetic process
0.43	GO:0042886	amide transport
0.43	GO:0009725	response to hormone

0.49	GO:0017137	Rab GTPase binding
0.44	GO:0003676	nucleic acid binding
0.42	GO:0046872	metal ion binding
0.41	GO:0003700	DNA binding transcription factor activity
0.40	GO:0070491	repressing transcription factor binding
0.38	GO:0003777	microtubule motor activity
0.37	GO:0004674	protein serine/threonine kinase activity
0.37	GO:0030554	adenyl nucleotide binding
0.36	GO:0097367	carbohydrate derivative binding
0.36	GO:0008144	drug binding

0.48	GO:0005634	nucleus
0.37	GO:0030286	dynein complex
0.36	GO:0061177	type Is terminal bouton
0.36	GO:0061176	type Ib terminal bouton
0.36	GO:0097482	muscle cell postsynaptic specialization
0.36	GO:0005700	polytene chromosome
0.35	GO:0034707	chloride channel complex
0.34	GO:0030529	intracellular ribonucleoprotein complex
0.34	GO:0005737	cytoplasm
0.34	GO:0070013	intracellular organelle lumen

0.37

GO:0004674

tr|T1FLT4|T1FLT4_HELRO
Uncharacterized protein
Search

tr|T1FLT5|T1FLT5_HELRO
Uncharacterized protein
Search

0.58	Endonuclease exonuclease phosphatase domain containing protein

0.64	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.49	GO:0006278	RNA-dependent DNA biosynthetic process

0.69	GO:0004527	exonuclease activity
0.66	GO:0004519	endonuclease activity
0.49	GO:0003964	RNA-directed DNA polymerase activity

0.49

EC:2.7.7.49

GO:0003964

tr|T1FLT6|T1FLT6_HELRO
Uncharacterized protein
Search

0.42	GO:0036211	protein modification process
0.40	GO:0006355	regulation of transcription, DNA-templated
0.40	GO:0044267	cellular protein metabolic process
0.38	GO:0016310	phosphorylation
0.38	GO:0016569	covalent chromatin modification
0.38	GO:0006396	RNA processing
0.37	GO:0098732	macromolecule deacylation
0.37	GO:0006914	autophagy
0.37	GO:0007018	microtubule-based movement
0.37	GO:0016072	rRNA metabolic process

0.45	GO:0003723	RNA binding
0.42	GO:0043565	sequence-specific DNA binding
0.41	GO:0140096	catalytic activity, acting on a protein
0.41	GO:0003700	DNA binding transcription factor activity
0.40	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.39	GO:0016301	kinase activity
0.39	GO:0032555	purine ribonucleotide binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0030554	adenyl nucleotide binding
0.38	GO:0008144	drug binding

0.40	GO:0030688	preribosome, small subunit precursor
0.37	GO:0005634	nucleus
0.37	GO:0020011	apicoplast
0.37	GO:0030681	multimeric ribonuclease P complex
0.35	GO:0005874	microtubule
0.35	GO:0031974	membrane-enclosed lumen
0.30	GO:0016020	membrane

0.40

GO:0016773

tr|T1FLT7|T1FLT7_HELRO
Uncharacterized protein
Search

tr|T1FLT8|T1FLT8_HELRO
Uncharacterized protein
Search

0.33	Voltage-gated potassium channel

0.78	GO:0051260	protein homooligomerization
0.74	GO:0034765	regulation of ion transmembrane transport
0.73	GO:0071805	potassium ion transmembrane transport
0.35	GO:0030431	sleep
0.34	GO:0006379	mRNA cleavage
0.32	GO:0006351	transcription, DNA-templated

0.78	GO:0005249	voltage-gated potassium channel activity
0.33	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.33	GO:0046872	metal ion binding
0.32	GO:0003676	nucleic acid binding

0.78

GO:0008076

voltage-gated potassium channel complex

0.33

GO:0003899

tr|T1FLT9|T1FLT9_HELRO
Uncharacterized protein
Search

tr|T1FLU0|T1FLU0_HELRO
Uncharacterized protein
Search

tr|T1FLU1|T1FLU1_HELRO
Uncharacterized protein
Search

0.44	GO:0019432	triglyceride biosynthetic process
0.41	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.41	GO:0051171	regulation of nitrogen compound metabolic process
0.41	GO:0080090	regulation of primary metabolic process
0.41	GO:0010468	regulation of gene expression
0.39	GO:0007017	microtubule-based process
0.39	GO:0006996	organelle organization
0.38	GO:0036211	protein modification process
0.38	GO:0044267	cellular protein metabolic process
0.38	GO:0097435	supramolecular fiber organization

0.44	GO:0004144	diacylglycerol O-acyltransferase activity
0.43	GO:0003676	nucleic acid binding
0.39	GO:0140110	transcription regulator activity
0.38	GO:0004842	ubiquitin-protein transferase activity
0.38	GO:0005515	protein binding
0.37	GO:0097367	carbohydrate derivative binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0017076	purine nucleotide binding
0.37	GO:0030695	GTPase regulator activity
0.37	GO:0042800	histone methyltransferase activity (H3-K4 specific)

0.48	GO:0005634	nucleus
0.40	GO:0005789	endoplasmic reticulum membrane
0.38	GO:0031592	centrosomal corona
0.37	GO:0030015	CCR4-NOT core complex
0.36	GO:0000932	P-body
0.36	GO:0034708	methyltransferase complex
0.36	GO:0000922	spindle pole
0.35	GO:0030286	dynein complex
0.35	GO:0070013	intracellular organelle lumen
0.30	GO:0016021	integral component of membrane

0.44	EC:2.3.1.20	GO:0004144
0.38	KEGG:R03876	GO:0004842

tr|T1FLU2|T1FLU2_HELRO
Uncharacterized protein
Search

tr|T1FLU3|T1FLU3_HELRO
Uncharacterized protein
Search

tr|T1FLU4|T1FLU4_HELRO
Uncharacterized protein
Search

tr|T1FLU5|T1FLU5_HELRO
Uncharacterized protein
Search

0.44	Endonuclease-reverse transcriptase HmRTE-e01

0.70	GO:0006278	RNA-dependent DNA biosynthetic process
0.64	GO:0090305	nucleic acid phosphodiester bond hydrolysis

0.70	GO:0003964	RNA-directed DNA polymerase activity
0.66	GO:0004519	endonuclease activity

0.70

EC:2.7.7.49

GO:0003964

tr|T1FLU6|T1FLU6_HELRO
Uncharacterized protein
Search

tr|T1FLU7|T1FLU7_HELRO
Uncharacterized protein
Search

tr|T1FLU8|T1FLU8_HELRO
Uncharacterized protein
Search

tr|T1FLU9|T1FLU9_HELRO
Uncharacterized protein
Search

0.42	GO:0006996	organelle organization
0.42	GO:0016567	protein ubiquitination
0.41	GO:0006353	DNA-templated transcription, termination
0.39	GO:0071539	protein localization to centrosome
0.38	GO:0033227	dsRNA transport
0.38	GO:0048211	Golgi vesicle docking
0.38	GO:0120031	plasma membrane bounded cell projection assembly
0.38	GO:0045056	transcytosis
0.37	GO:0006281	DNA repair
0.37	GO:0009405	pathogenesis

0.43	GO:0005509	calcium ion binding
0.41	GO:0008484	sulfuric ester hydrolase activity
0.41	GO:0004842	ubiquitin-protein transferase activity
0.38	GO:0005515	protein binding
0.37	GO:0030554	adenyl nucleotide binding
0.37	GO:0004222	metalloendopeptidase activity
0.37	GO:0097367	carbohydrate derivative binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:1990841	promoter-specific chromatin binding

0.41	GO:0005694	chromosome
0.39	GO:0031981	nuclear lumen
0.38	GO:0033202	DNA helicase complex
0.38	GO:0005813	centrosome
0.36	GO:0012507	ER to Golgi transport vesicle membrane
0.36	GO:0005795	Golgi stack
0.36	GO:0048471	perinuclear region of cytoplasm
0.36	GO:1904949	ATPase complex
0.36	GO:0000139	Golgi membrane
0.35	GO:0005783	endoplasmic reticulum

0.41	EC:3.1.6	GO:0008484
0.41	KEGG:R03876	GO:0004842

tr|T1FLV0|T1FLV0_HELRO
Uncharacterized protein
Search

tr|T1FLV1|T1FLV1_HELRO
Uncharacterized protein
Search

tr|T1FLV2|T1FLV2_HELRO
Uncharacterized protein
Search

tr|T1FLV3|T1FLV3_HELRO
Uncharacterized protein
Search

tr|T1FLV4|T1FLV4_HELRO
Ribosomal protein L19
Search

0.45	Ribosomal protein L19

0.60	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.35	GO:0008340	determination of adult lifespan
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0030097	hemopoiesis
0.33	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.33	GO:0019083	viral transcription
0.33	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic

0.63	GO:0003735	structural constituent of ribosome
0.37	GO:0003723	RNA binding
0.33	GO:0005515	protein binding
0.33	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.33	GO:0050660	flavin adenine dinucleotide binding
0.32	GO:0016491	oxidoreductase activity

0.78	GO:0022625	cytosolic large ribosomal subunit
0.41	GO:0042788	polysomal ribosome
0.34	GO:0005925	focal adhesion
0.33	GO:0019013	viral nucleocapsid
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:3.1.26.4

GO:0004523

tr|T1FLV5|T1FLV5_HELRO
Uncharacterized protein
Search

0.47	GO:0046907	intracellular transport
0.46	GO:0070727	cellular macromolecule localization
0.46	GO:0015031	protein transport
0.43	GO:0006357	regulation of transcription by RNA polymerase II
0.40	GO:0071840	cellular component organization or biogenesis
0.39	GO:0001522	pseudouridine synthesis
0.38	GO:0048193	Golgi vesicle transport
0.38	GO:0007274	neuromuscular synaptic transmission
0.38	GO:0042551	neuron maturation
0.37	GO:0048167	regulation of synaptic plasticity

0.51	GO:0017137	Rab GTPase binding
0.46	GO:0003712	transcription cofactor activity
0.46	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.42	GO:0046872	metal ion binding
0.40	GO:0046983	protein dimerization activity
0.40	GO:0003676	nucleic acid binding
0.38	GO:0016286	small conductance calcium-activated potassium channel activity
0.37	GO:0004402	histone acetyltransferase activity
0.37	GO:0005198	structural molecule activity
0.37	GO:0008017	microtubule binding

0.46	GO:0016592	mediator complex
0.38	GO:0012505	endomembrane system
0.38	GO:0048788	cytoskeleton of presynaptic active zone
0.37	GO:0098588	bounding membrane of organelle
0.37	GO:0005694	chromosome
0.36	GO:0005882	intermediate filament
0.36	GO:0030134	COPII-coated ER to Golgi transport vesicle
0.36	GO:0030659	cytoplasmic vesicle membrane
0.36	GO:0005911	cell-cell junction
0.36	GO:0030117	membrane coat

0.37

GO:0004402

tr|T1FLV6|T1FLV6_HELRO
Uncharacterized protein
Search

0.55

GO:0003677

DNA binding

tr|T1FLV7|T1FLV7_HELRO
Uncharacterized protein
Search

0.39	GO:0019538	protein metabolic process
0.38	GO:0043412	macromolecule modification
0.38	GO:0097659	nucleic acid-templated transcription
0.38	GO:0065007	biological regulation
0.38	GO:0044260	cellular macromolecule metabolic process
0.38	GO:0006325	chromatin organization
0.38	GO:0010467	gene expression
0.37	GO:0016310	phosphorylation
0.36	GO:0051716	cellular response to stimulus
0.36	GO:0007154	cell communication

0.40	GO:0140096	catalytic activity, acting on a protein
0.39	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.39	GO:0003676	nucleic acid binding
0.39	GO:0017171	serine hydrolase activity
0.38	GO:0030554	adenyl nucleotide binding
0.38	GO:0097367	carbohydrate derivative binding
0.38	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0008144	drug binding
0.38	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.37	GO:0016301	kinase activity

0.41	GO:0005634	nucleus
0.37	GO:0070013	intracellular organelle lumen
0.36	GO:0044446	intracellular organelle part
0.36	GO:0000313	organellar ribosome
0.36	GO:1990234	transferase complex
0.34	GO:0005739	mitochondrion
0.34	GO:0005615	extracellular space
0.34	GO:0048786	presynaptic active zone
0.33	GO:0005694	chromosome
0.33	GO:0043234	protein complex

0.39

GO:0003899

tr|T1FLV8|T1FLV8_HELRO
Uncharacterized protein
Search

tr|T1FLV9|T1FLV9_HELRO
Uncharacterized protein
Search

0.47	SET domain-containing protein

tr|T1FLW0|T1FLW0_HELRO
Uncharacterized protein
Search

tr|T1FLW1|T1FLW1_HELRO
Uncharacterized protein
Search

tr|T1FLW2|T1FLW2_HELRO
Uncharacterized protein
Search

tr|T1FLW3|T1FLW3_HELRO
Uncharacterized protein
Search

0.48	GO:0043044	ATP-dependent chromatin remodeling
0.42	GO:2001141	regulation of RNA biosynthetic process
0.42	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.41	GO:0010468	regulation of gene expression
0.39	GO:0035023	regulation of Rho protein signal transduction
0.38	GO:0019538	protein metabolic process
0.38	GO:0006401	RNA catabolic process
0.38	GO:0006928	movement of cell or subcellular component
0.38	GO:0016310	phosphorylation
0.37	GO:0000001	mitochondrion inheritance

0.44	GO:0003676	nucleic acid binding
0.43	GO:0030554	adenyl nucleotide binding
0.43	GO:0003700	DNA binding transcription factor activity
0.43	GO:0008270	zinc ion binding
0.43	GO:0097367	carbohydrate derivative binding
0.43	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0008144	drug binding
0.39	GO:0004386	helicase activity
0.39	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.39	GO:0140096	catalytic activity, acting on a protein

0.42	GO:0005634	nucleus
0.38	GO:0044446	intracellular organelle part
0.37	GO:0005615	extracellular space
0.36	GO:0031461	cullin-RING ubiquitin ligase complex
0.36	GO:0031090	organelle membrane
0.35	GO:0005794	Golgi apparatus
0.35	GO:0005783	endoplasmic reticulum
0.35	GO:0015630	microtubule cytoskeleton
0.34	GO:0005739	mitochondrion
0.34	GO:0031975	envelope

0.38	EC:2.7.1	GO:0016773
0.37	KEGG:R05982 KEGG:R06722	GO:0004571

tr|T1FLW4|T1FLW4_HELRO
Uncharacterized protein
Search

0.85	GO:0061015	snRNA import into nucleus
0.78	GO:0006606	protein import into nucleus
0.39	GO:0006370	7-methylguanosine mRNA capping
0.36	GO:0045903	positive regulation of translational fidelity
0.35	GO:0022613	ribonucleoprotein complex biogenesis
0.35	GO:0000398	mRNA splicing, via spliceosome
0.35	GO:0035335	peptidyl-tyrosine dephosphorylation
0.34	GO:0071826	ribonucleoprotein complex subunit organization
0.34	GO:0034622	cellular macromolecular complex assembly
0.34	GO:0016072	rRNA metabolic process

0.81	GO:0061608	nuclear import signal receptor activity
0.57	GO:0008565	protein transporter activity
0.50	GO:0003723	RNA binding
0.40	GO:0004484	mRNA guanylyltransferase activity
0.35	GO:0004725	protein tyrosine phosphatase activity
0.34	GO:0003735	structural constituent of ribosome
0.33	GO:0005515	protein binding

0.58	GO:0005634	nucleus
0.47	GO:0005737	cytoplasm
0.37	GO:0070062	extracellular exosome
0.35	GO:0005846	nuclear cap binding complex
0.35	GO:0012505	endomembrane system
0.35	GO:0044446	intracellular organelle part
0.35	GO:0030686	90S preribosome
0.35	GO:0043234	protein complex
0.35	GO:0032040	small-subunit processome
0.35	GO:0043233	organelle lumen

0.40

EC:2.7.7.50

GO:0004484

tr|T1FLW5|T1FLW5_HELRO
Uncharacterized protein
Search

0.43	GO:0000256	allantoin catabolic process
0.39	GO:0065007	biological regulation
0.39	GO:0042147	retrograde transport, endosome to Golgi
0.38	GO:0048856	anatomical structure development
0.38	GO:0006323	DNA packaging
0.37	GO:0051703	intraspecies interaction between organisms
0.37	GO:0022607	cellular component assembly
0.37	GO:0022402	cell cycle process
0.37	GO:0051716	cellular response to stimulus
0.37	GO:0023052	signaling

0.45	GO:0003723	RNA binding
0.44	GO:0004037	allantoicase activity
0.41	GO:0017076	purine nucleotide binding
0.41	GO:0097367	carbohydrate derivative binding
0.41	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0008144	drug binding
0.39	GO:0005515	protein binding
0.38	GO:0003700	DNA binding transcription factor activity
0.37	GO:0000285	1-phosphatidylinositol-3-phosphate 5-kinase activity
0.37	GO:0140096	catalytic activity, acting on a protein

0.40	GO:0005634	nucleus
0.39	GO:0005667	transcription factor complex
0.37	GO:0044446	intracellular organelle part
0.37	GO:0098588	bounding membrane of organelle
0.37	GO:0032045	guanyl-nucleotide exchange factor complex
0.37	GO:0048786	presynaptic active zone
0.37	GO:0005829	cytosol
0.36	GO:0000793	condensed chromosome
0.36	GO:0012505	endomembrane system
0.36	GO:0044815	DNA packaging complex

0.44	EC:3.5.3.4	GO:0004037
0.44	KEGG:R02422	GO:0004037

tr|T1FLW6|T1FLW6_HELRO
Uncharacterized protein
Search

tr|T1FLW7|T1FLW7_HELRO
Uncharacterized protein
Search

0.12	C2H2-type zinc finger transcription factor (Fragment)

0.51	GO:0003676	nucleic acid binding
0.38	GO:0016788	hydrolase activity, acting on ester bonds

0.30

GO:0016021

integral component of membrane

0.38

GO:0016788

tr|T1FLW8|T1FLW8_HELRO
Uncharacterized protein
Search

0.50	RNA ligase

0.34

GO:0016556

mRNA modification

0.82	GO:0003972	RNA ligase (ATP) activity
0.53	GO:0030554	adenyl nucleotide binding
0.52	GO:0097367	carbohydrate derivative binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003723	RNA binding

0.35

GO:0031019

mitochondrial mRNA editing complex

0.82

EC:6.5.1.3

GO:0003972

tr|T1FLW9|T1FLW9_HELRO
Uncharacterized protein
Search

0.43	GO:0007018	microtubule-based movement
0.40	GO:0007186	G-protein coupled receptor signaling pathway
0.40	GO:0006629	lipid metabolic process
0.38	GO:0099120	socially cooperative development
0.38	GO:2001141	regulation of RNA biosynthetic process
0.38	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.37	GO:0010468	regulation of gene expression
0.37	GO:0043412	macromolecule modification
0.37	GO:0044260	cellular macromolecule metabolic process
0.36	GO:0019538	protein metabolic process

0.44	GO:0008502	melatonin receptor activity
0.43	GO:0003777	microtubule motor activity
0.42	GO:0008017	microtubule binding
0.41	GO:0008270	zinc ion binding
0.40	GO:0003725	double-stranded RNA binding
0.39	GO:0030554	adenyl nucleotide binding
0.39	GO:0140110	transcription regulator activity
0.39	GO:0097367	carbohydrate derivative binding
0.39	GO:0008144	drug binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding

0.39	GO:0005634	nucleus
0.37	GO:0005667	transcription factor complex
0.35	GO:0005694	chromosome
0.35	GO:0044446	intracellular organelle part
0.34	GO:0012505	endomembrane system
0.33	GO:0070013	intracellular organelle lumen
0.33	GO:0015630	microtubule cytoskeleton
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.37	EC:2.7	GO:0016772
0.34	KEGG:R03430	GO:0052659

tr|T1FLX0|T1FLX0_HELRO
Uncharacterized protein
Search

tr|T1FLX1|T1FLX1_HELRO
Uncharacterized protein
Search

tr|T1FLX2|T1FLX2_HELRO
Uncharacterized protein
Search

0.44	GO:0000256	allantoin catabolic process
0.43	GO:0019538	protein metabolic process
0.42	GO:0051028	mRNA transport
0.42	GO:0043412	macromolecule modification
0.41	GO:0060255	regulation of macromolecule metabolic process
0.40	GO:0051171	regulation of nitrogen compound metabolic process
0.40	GO:0080090	regulation of primary metabolic process
0.40	GO:0016310	phosphorylation
0.39	GO:0031323	regulation of cellular metabolic process
0.39	GO:0009889	regulation of biosynthetic process

0.45	GO:0004037	allantoicase activity
0.45	GO:0140096	catalytic activity, acting on a protein
0.42	GO:0030554	adenyl nucleotide binding
0.42	GO:0097367	carbohydrate derivative binding
0.42	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0008144	drug binding
0.41	GO:0016887	ATPase activity
0.40	GO:0016301	kinase activity
0.40	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.39	GO:0008270	zinc ion binding

0.47	GO:0009376	HslUV protease complex
0.43	GO:0005643	nuclear pore
0.38	GO:0019005	SCF ubiquitin ligase complex
0.36	GO:0000932	P-body
0.36	GO:0034399	nuclear periphery
0.36	GO:0000178	exosome (RNase complex)
0.36	GO:1990745	EARP complex
0.36	GO:0000938	GARP complex
0.35	GO:0030117	membrane coat
0.35	GO:0020036	Maurer's cleft

0.45	EC:3.5.3.4	GO:0004037
0.45	KEGG:R02422	GO:0004037

tr|T1FLX3|T1FLX3_HELRO
Uncharacterized protein
Search

0.34	Cytochrome c oxidase subunit 3

0.75	GO:0019646	aerobic electron transport chain
0.63	GO:1902600	hydrogen ion transmembrane transport

0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity

0.61	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.65

EC:1.9.3

GO:0016676

tr|T1FLX4|T1FLX4_HELRO
Uncharacterized protein
Search

tr|T1FLX5|T1FLX5_HELRO
Uncharacterized protein
Search

tr|T1FLX6|T1FLX6_HELRO
Uncharacterized protein
Search

0.42	GO:1903506	regulation of nucleic acid-templated transcription
0.42	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.42	GO:0030154	cell differentiation
0.42	GO:0010468	regulation of gene expression
0.40	GO:0007049	cell cycle
0.39	GO:0007275	multicellular organism development
0.39	GO:0006468	protein phosphorylation
0.38	GO:0009653	anatomical structure morphogenesis
0.38	GO:0016043	cellular component organization
0.37	GO:1902679	negative regulation of RNA biosynthetic process

0.46	GO:0003676	nucleic acid binding
0.41	GO:0140110	transcription regulator activity
0.41	GO:0003682	chromatin binding
0.39	GO:0004672	protein kinase activity
0.39	GO:0005515	protein binding
0.37	GO:0030554	adenyl nucleotide binding
0.37	GO:0008270	zinc ion binding
0.37	GO:0097367	carbohydrate derivative binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding

0.45	GO:0005634	nucleus
0.37	GO:0070013	intracellular organelle lumen
0.36	GO:0005813	centrosome
0.36	GO:0032991	macromolecular complex
0.36	GO:0005694	chromosome
0.35	GO:0051233	spindle midzone
0.35	GO:0005876	spindle microtubule
0.35	GO:0000922	spindle pole
0.34	GO:0005737	cytoplasm
0.33	GO:0012505	endomembrane system

0.34

GO:0008483

tr|T1FLX7|T1FLX7_HELRO
Uncharacterized protein
Search

tr|T1FLX8|T1FLX8_HELRO
Uncharacterized protein
Search

tr|T1FLX9|T1FLX9_HELRO
Uncharacterized protein
Search

tr|T1FLY0|T1FLY0_HELRO
Uncharacterized protein
Search

tr|T1FLY1|T1FLY1_HELRO
Uncharacterized protein
Search

tr|T1FLY2|T1FLY2_HELRO
Uncharacterized protein
Search

tr|T1FLY3|T1FLY3_HELRO
Uncharacterized protein
Search

tr|T1FLY4|T1FLY4_HELRO
Uncharacterized protein
Search

tr|T1FLY5|T1FLY5_HELRO
Uncharacterized protein
Search

tr|T1FLY6|T1FLY6_HELRO
Uncharacterized protein
Search

tr|T1FLY7|T1FLY7_HELRO
Uncharacterized protein
Search

tr|T1FLY8|T1FLY8_HELRO
Uncharacterized protein
Search

tr|T1FLY9|T1FLY9_HELRO
Uncharacterized protein
Search

tr|T1FLZ0|T1FLZ0_HELRO
Uncharacterized protein
Search

tr|T1FLZ1|T1FLZ1_HELRO
Uncharacterized protein
Search

0.46	GO:0000723	telomere maintenance
0.43	GO:0032392	DNA geometric change
0.42	GO:0006310	DNA recombination
0.42	GO:0016567	protein ubiquitination
0.42	GO:0006281	DNA repair
0.39	GO:0006836	neurotransmitter transport
0.35	GO:0055085	transmembrane transport

0.63	GO:0004386	helicase activity
0.52	GO:0032559	adenyl ribonucleotide binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0003676	nucleic acid binding
0.42	GO:0004842	ubiquitin-protein transferase activity
0.41	GO:0140097	catalytic activity, acting on DNA
0.39	GO:0005328	neurotransmitter:sodium symporter activity

0.30

GO:0016020

membrane

0.42

GO:0004842

tr|T1FLZ2|T1FLZ2_HELRO
Uncharacterized protein
Search

0.47

GO:0090305

nucleic acid phosphodiester bond hydrolysis

0.50	GO:0004527	exonuclease activity
0.48	GO:0004519	endonuclease activity

0.30

GO:0031224

intrinsic component of membrane

tr|T1FLZ3|T1FLZ3_HELRO
Uncharacterized protein
Search

tr|T1FLZ4|T1FLZ4_HELRO
Uncharacterized protein
Search

tr|T1FLZ5|T1FLZ5_HELRO
Uncharacterized protein
Search

tr|T1FLZ6|T1FLZ6_HELRO
Uncharacterized protein
Search

tr|T1FLZ7|T1FLZ7_HELRO
Uncharacterized protein
Search

tr|T1FLZ8|T1FLZ8_HELRO
Uncharacterized protein
Search

tr|T1FLZ9|T1FLZ9_HELRO
Uncharacterized protein
Search

0.71	GO:0009734	auxin-activated signaling pathway
0.53	GO:0006351	transcription, DNA-templated
0.53	GO:2001141	regulation of RNA biosynthetic process
0.53	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.53	GO:0010468	regulation of gene expression
0.46	GO:0036011	imaginal disc-derived leg segmentation
0.45	GO:0120036	plasma membrane bounded cell projection organization
0.45	GO:0048699	generation of neurons
0.42	GO:0048468	cell development
0.42	GO:0048800	antennal morphogenesis

0.51	GO:0003677	DNA binding
0.45	GO:0030507	spectrin binding
0.43	GO:0005516	calmodulin binding
0.42	GO:0008017	microtubule binding
0.41	GO:0005112	Notch binding
0.40	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.40	GO:0046983	protein dimerization activity
0.40	GO:0004363	glutathione synthase activity
0.39	GO:0003682	chromatin binding
0.39	GO:0008270	zinc ion binding

0.57	GO:0005634	nucleus
0.42	GO:0005874	microtubule
0.40	GO:0070013	intracellular organelle lumen
0.39	GO:0031248	protein acetyltransferase complex
0.39	GO:0005667	transcription factor complex
0.38	GO:1905368	peptidase complex
0.38	GO:0000785	chromatin
0.37	GO:1904949	ATPase complex
0.35	GO:0005737	cytoplasm

0.40	EC:6.3.2.3	GO:0004363
0.40	KEGG:R00497	GO:0004363

tr|T1FM00|T1FM00_HELRO
Uncharacterized protein
Search

0.52	GO:0016573	histone acetylation
0.47	GO:0044265	cellular macromolecule catabolic process
0.43	GO:0034655	nucleobase-containing compound catabolic process
0.43	GO:0016071	mRNA metabolic process
0.43	GO:0010629	negative regulation of gene expression
0.42	GO:0000055	ribosomal large subunit export from nucleus
0.42	GO:0030163	protein catabolic process
0.41	GO:0042273	ribosomal large subunit biogenesis
0.40	GO:0030036	actin cytoskeleton organization
0.40	GO:0006508	proteolysis

0.53	GO:0004402	histone acetyltransferase activity
0.39	GO:0004722	protein serine/threonine phosphatase activity
0.38	GO:0003676	nucleic acid binding
0.38	GO:0046872	metal ion binding
0.37	GO:0003700	DNA binding transcription factor activity
0.36	GO:0004674	protein serine/threonine kinase activity
0.36	GO:0009982	pseudouridine synthase activity
0.36	GO:0031593	polyubiquitin modification-dependent protein binding
0.35	GO:0030554	adenyl nucleotide binding
0.35	GO:0097367	carbohydrate derivative binding

0.48	GO:0030014	CCR4-NOT complex
0.45	GO:0008540	proteasome regulatory particle, base subcomplex
0.38	GO:0005634	nucleus
0.37	GO:0005881	cytoplasmic microtubule
0.37	GO:0005815	microtubule organizing center
0.35	GO:0035003	subapical complex
0.35	GO:0016327	apicolateral plasma membrane
0.35	GO:0045179	apical cortex
0.35	GO:0000808	origin recognition complex
0.35	GO:0000932	P-body

0.53	EC:2.3.1.48	GO:0004402
0.35	KEGG:R03876	GO:0004842

tr|T1FM01|T1FM01_HELRO
Uncharacterized protein
Search

tr|T1FM02|T1FM02_HELRO
Uncharacterized protein
Search

tr|T1FM03|T1FM03_HELRO
Uncharacterized protein
Search

tr|T1FM04|T1FM04_HELRO
Uncharacterized protein
Search

0.70	GO:0006334	nucleosome assembly
0.38	GO:0007166	cell surface receptor signaling pathway
0.36	GO:0007186	G-protein coupled receptor signaling pathway
0.36	GO:0010629	negative regulation of gene expression
0.36	GO:0044267	cellular protein metabolic process
0.36	GO:1903507	negative regulation of nucleic acid-templated transcription
0.36	GO:0009116	nucleoside metabolic process
0.36	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
0.36	GO:0051301	cell division
0.35	GO:1904668	positive regulation of ubiquitin protein ligase activity

0.51	GO:0003677	DNA binding
0.38	GO:0016757	transferase activity, transferring glycosyl groups
0.36	GO:0004930	G-protein coupled receptor activity
0.36	GO:0003682	chromatin binding
0.36	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.36	GO:0097367	carbohydrate derivative binding
0.36	GO:0017111	nucleoside-triphosphatase activity
0.35	GO:0043168	anion binding
0.35	GO:1901265	nucleoside phosphate binding
0.35	GO:0097027	ubiquitin-protein transferase activator activity

0.66	GO:0000786	nucleosome
0.36	GO:0005876	spindle microtubule
0.36	GO:0000940	condensed chromosome outer kinetochore
0.35	GO:0000139	Golgi membrane
0.35	GO:0048500	signal recognition particle
0.34	GO:0015934	large ribosomal subunit
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.38

EC:2.4

GO:0016757

tr|T1FM05|T1FM05_HELRO
Uncharacterized protein
Search

tr|T1FM06|T1FM06_HELRO
Uncharacterized protein
Search

tr|T1FM07|T1FM07_HELRO
Uncharacterized protein
Search

tr|T1FM08|T1FM08_HELRO
Uncharacterized protein
Search

0.43	GO:0000495	box H/ACA snoRNA 3'-end processing
0.43	GO:0043412	macromolecule modification
0.42	GO:0006364	rRNA processing
0.42	GO:0016311	dephosphorylation
0.41	GO:0016073	snRNA metabolic process
0.39	GO:0044267	cellular protein metabolic process
0.39	GO:0016071	mRNA metabolic process
0.38	GO:0060294	cilium movement involved in cell motility
0.38	GO:0006457	protein folding
0.37	GO:0034728	nucleosome organization

0.44	GO:0003723	RNA binding
0.43	GO:0004722	protein serine/threonine phosphatase activity
0.41	GO:0009982	pseudouridine synthase activity
0.38	GO:0005515	protein binding
0.37	GO:0043874	acireductone synthase activity
0.37	GO:0043716	2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase activity
0.37	GO:0043715	2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity
0.36	GO:0005216	ion channel activity
0.36	GO:0003682	chromatin binding
0.36	GO:0043168	anion binding

0.46	GO:0005732	small nucleolar ribonucleoprotein complex
0.45	GO:0044452	nucleolar part
0.41	GO:0032040	small-subunit processome
0.39	GO:0005929	cilium
0.39	GO:0032838	plasma membrane bounded cell projection cytoplasm
0.39	GO:1902494	catalytic complex
0.37	GO:0012505	endomembrane system
0.37	GO:0044430	cytoskeletal part
0.36	GO:0000785	chromatin
0.36	GO:0090575	RNA polymerase II transcription factor complex

0.41	EC:5.4.99.12	GO:0009982
0.37	KEGG:R07394	GO:0043716

tr|T1FM09|T1FM09_HELRO
Uncharacterized protein
Search

tr|T1FM10|T1FM10_HELRO
Uncharacterized protein
Search

0.44	GO:0044267	cellular protein metabolic process
0.43	GO:0036211	protein modification process
0.42	GO:0016310	phosphorylation
0.41	GO:0006518	peptide metabolic process
0.41	GO:0043604	amide biosynthetic process
0.40	GO:0010467	gene expression
0.40	GO:0032790	ribosome disassembly
0.39	GO:1901566	organonitrogen compound biosynthetic process
0.39	GO:0009059	macromolecule biosynthetic process
0.39	GO:0009166	nucleotide catabolic process

0.44	GO:0004672	protein kinase activity
0.41	GO:0032559	adenyl ribonucleotide binding
0.41	GO:0043168	anion binding
0.41	GO:0008144	drug binding
0.41	GO:0003676	nucleic acid binding
0.41	GO:0030246	carbohydrate binding
0.39	GO:0008253	5'-nucleotidase activity
0.38	GO:0043023	ribosomal large subunit binding
0.37	GO:0070035	purine NTP-dependent helicase activity
0.37	GO:0004252	serine-type endopeptidase activity

0.43	GO:0009536	plastid
0.35	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.39

EC:3.1.3.5

GO:0008253

tr|T1FM11|T1FM11_HELRO
Uncharacterized protein
Search

SCAI

0.86	Suppressor of cancer cell invasion (Fragment)

0.72	GO:1903507	negative regulation of nucleic acid-templated transcription
0.58	GO:0006351	transcription, DNA-templated
0.52	GO:0035024	negative regulation of Rho protein signal transduction
0.46	GO:0030336	negative regulation of cell migration
0.38	GO:0006355	regulation of transcription, DNA-templated
0.33	GO:0016575	histone deacetylation

0.81	GO:0003714	transcription corepressor activity
0.33	GO:0005515	protein binding

0.45	GO:0031965	nuclear membrane
0.37	GO:0005737	cytoplasm
0.33	GO:0005654	nucleoplasm
0.30	GO:0016021	integral component of membrane

tr|T1FM12|T1FM12_HELRO
Uncharacterized protein
Search

tr|T1FM13|T1FM13_HELRO
Uncharacterized protein
Search

tr|T1FM14|T1FM14_HELRO
Uncharacterized protein
Search

RNF2

0.74	E3 ubiquitin-protein ligase RING2-A

0.53	GO:0036353	histone H2A-K119 monoubiquitination
0.48	GO:0001702	gastrulation with mouth forming second
0.48	GO:0000122	negative regulation of transcription by RNA polymerase II
0.47	GO:0009948	anterior/posterior axis specification
0.47	GO:0043433	negative regulation of DNA binding transcription factor activity
0.45	GO:0007281	germ cell development
0.44	GO:0000278	mitotic cell cycle
0.38	GO:0006351	transcription, DNA-templated
0.37	GO:0048513	animal organ development
0.37	GO:0070317	negative regulation of G0 to G1 transition

0.61	GO:0016874	ligase activity
0.50	GO:0071535	RING-like zinc finger domain binding
0.45	GO:0003682	chromatin binding
0.44	GO:0061630	ubiquitin protein ligase activity
0.41	GO:0008270	zinc ion binding
0.36	GO:0005544	calcium-dependent phospholipid binding
0.34	GO:0005509	calcium ion binding

0.61	GO:0035102	PRC1 complex
0.49	GO:0071339	MLL1 complex
0.49	GO:0001739	sex chromatin
0.47	GO:0000791	euchromatin
0.45	GO:0016604	nuclear body

0.61

GO:0016874

tr|T1FM15|T1FM15_HELRO
Uncharacterized protein
Search

0.95	Adaptor protein pellino

0.85	GO:0008063	Toll signaling pathway
0.46	GO:0045751	negative regulation of Toll signaling pathway
0.46	GO:1902524	positive regulation of protein K48-linked ubiquitination
0.46	GO:0008348	negative regulation of antimicrobial humoral response
0.44	GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway
0.42	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway
0.41	GO:0042325	regulation of phosphorylation
0.39	GO:0000209	protein polyubiquitination
0.37	GO:0006955	immune response
0.35	GO:0070434	positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway

0.42	GO:0019207	kinase regulator activity
0.39	GO:0061630	ubiquitin protein ligase activity
0.38	GO:0016874	ligase activity
0.33	GO:0004252	serine-type endopeptidase activity

0.37	GO:0005886	plasma membrane
0.35	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.38

GO:0016874

tr|T1FM16|T1FM16_HELRO
Uncharacterized protein
Search

tr|T1FM17|T1FM17_HELRO
ER membrane protein complex subunit 4
Search

0.50	ER membrane protein complex subunit

0.46	GO:0034975	protein folding in endoplasmic reticulum
0.38	GO:0006508	proteolysis
0.37	GO:0006915	apoptotic process
0.34	GO:0031929	TOR signaling

0.40

GO:0004252

serine-type endopeptidase activity

0.51	GO:0072546	ER membrane protein complex
0.34	GO:0031932	TORC2 complex

0.40

GO:0004252

tr|T1FM18|T1FM18_HELRO
Uncharacterized protein
Search

0.68	Guanine nucleotide-binding protein Gq alpha subunit

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.53	GO:0045634	regulation of melanocyte differentiation
0.51	GO:0001508	action potential
0.50	GO:0048066	developmental pigmentation
0.50	GO:0007603	phototransduction, visible light
0.50	GO:0009649	entrainment of circadian clock
0.49	GO:0042711	maternal behavior
0.49	GO:1905145	cellular response to acetylcholine
0.49	GO:1903831	signal transduction involved in cellular response to ammonium ion
0.48	GO:0001501	skeletal system development

0.81	GO:0031683	G-protein beta/gamma-subunit complex binding
0.81	GO:0001664	G-protein coupled receptor binding
0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.64	GO:0004871	signal transducer activity
0.44	GO:0005096	GTPase activator activity
0.40	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity
0.36	GO:0046872	metal ion binding
0.33	GO:0016874	ligase activity

0.49	GO:0043005	neuron projection
0.48	GO:0097731	9+0 non-motile cilium
0.48	GO:0120038	plasma membrane bounded cell projection part
0.46	GO:0044297	cell body
0.46	GO:0036477	somatodendritic compartment
0.44	GO:1905360	GTPase complex
0.44	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.40	GO:0044422	organelle part
0.40	GO:0098797	plasma membrane protein complex
0.37	GO:0070062	extracellular exosome

0.40

EC:3.1.4.39

GO:0047391

tr|T1FM19|T1FM19_HELRO
Peptidyl-prolyl cis-trans isomerase
Search

0.42	Peptidyl-prolyl cis-trans isomerase

0.71	GO:0000413	protein peptidyl-prolyl isomerization
0.65	GO:0006457	protein folding
0.32	GO:0005975	carbohydrate metabolic process

0.71	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.33	GO:0016018	cyclosporin A binding
0.32	GO:0003924	GTPase activity
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0019001	guanyl nucleotide binding
0.32	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.31	GO:0032555	purine ribonucleotide binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.34	GO:0043231	intracellular membrane-bounded organelle
0.33	GO:0005829	cytosol
0.33	GO:0005768	endosome
0.33	GO:0005886	plasma membrane
0.32	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.71

GO:0003755

tr|T1FM20|T1FM20_HELRO
Uncharacterized protein
Search

PSMC3

0.72	26S protease regulatory subunit

0.81	GO:1901800	positive regulation of proteasomal protein catabolic process
0.70	GO:0030163	protein catabolic process
0.53	GO:0006508	proteolysis
0.42	GO:0043632	modification-dependent macromolecule catabolic process
0.42	GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly
0.40	GO:0034976	response to endoplasmic reticulum stress
0.40	GO:0010243	response to organonitrogen compound
0.38	GO:0044267	cellular protein metabolic process
0.36	GO:0052472	modulation by host of symbiont transcription
0.36	GO:0001824	blastocyst development

0.82	GO:0036402	proteasome-activating ATPase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0008233	peptidase activity
0.41	GO:0017025	TBP-class protein binding
0.35	GO:0042802	identical protein binding
0.34	GO:0008568	microtubule-severing ATPase activity

0.50	GO:1905369	endopeptidase complex
0.49	GO:0005737	cytoplasm
0.44	GO:0043234	protein complex
0.38	GO:0031981	nuclear lumen
0.35	GO:0035770	ribonucleoprotein granule

0.52

GO:0008233

tr|T1FM21|T1FM21_HELRO
Uncharacterized protein
Search

0.46	Zinc transporter

0.66	GO:0030001	metal ion transport
0.55	GO:0055085	transmembrane transport
0.43	GO:0072511	divalent inorganic cation transport
0.37	GO:0043043	peptide biosynthetic process
0.36	GO:0044267	cellular protein metabolic process
0.36	GO:0010467	gene expression
0.35	GO:0009059	macromolecule biosynthetic process
0.33	GO:0007165	signal transduction

0.68	GO:0046873	metal ion transmembrane transporter activity
0.44	GO:0072509	divalent inorganic cation transmembrane transporter activity
0.38	GO:0003735	structural constituent of ribosome

0.37	GO:0005840	ribosome
0.30	GO:0044425	membrane part

tr|T1FM22|T1FM22_HELRO
Uncharacterized protein
Search

TLE3

0.62	Co-repressor protein groucho

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.34	GO:0016055	Wnt signaling pathway
0.33	GO:0006468	protein phosphorylation
0.32	GO:0006351	transcription, DNA-templated

0.34	GO:0016905	myosin heavy chain kinase activity
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.42	GO:0005667	transcription factor complex
0.41	GO:0031974	membrane-enclosed lumen
0.38	GO:0044446	intracellular organelle part

0.34

EC:2.7.11.7

GO:0016905

tr|T1FM23|T1FM23_HELRO
Uncharacterized protein
Search

0.41	GO:0000122	negative regulation of transcription by RNA polymerase II
0.40	GO:0035074	pupation
0.39	GO:0071390	cellular response to ecdysone
0.39	GO:0006366	transcription by RNA polymerase II
0.39	GO:0035152	regulation of tube architecture, open tracheal system
0.39	GO:0045944	positive regulation of transcription by RNA polymerase II
0.37	GO:0035264	multicellular organism growth
0.37	GO:0003261	cardiac muscle progenitor cell migration to the midline involved in heart field formation
0.36	GO:0008078	mesodermal cell migration
0.36	GO:0042074	cell migration involved in gastrulation

0.51	GO:0003676	nucleic acid binding
0.43	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.39	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.38	GO:0042803	protein homodimerization activity
0.38	GO:0046872	metal ion binding
0.33	GO:0042302	structural constituent of cuticle
0.32	GO:0005044	scavenger receptor activity
0.32	GO:0046923	ER retention sequence binding
0.31	GO:0016491	oxidoreductase activity

0.41	GO:0005634	nucleus
0.32	GO:0005783	endoplasmic reticulum
0.30	GO:0016020	membrane

0.31

GO:0016491

tr|T1FM24|T1FM24_HELRO
Uncharacterized protein
Search

STRAP

0.84	serine-threonine kinase receptor-associated protein-like

0.52	GO:0016310	phosphorylation
0.47	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation
0.47	GO:0030277	maintenance of gastrointestinal epithelium
0.47	GO:0010719	negative regulation of epithelial to mesenchymal transition
0.46	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.46	GO:0010633	negative regulation of epithelial cell migration
0.46	GO:0007476	imaginal disc-derived wing morphogenesis
0.46	GO:0050680	negative regulation of epithelial cell proliferation
0.45	GO:0000387	spliceosomal snRNP assembly
0.44	GO:0000122	negative regulation of transcription by RNA polymerase II

0.54	GO:0016301	kinase activity
0.43	GO:0005102	receptor binding
0.35	GO:0003723	RNA binding

0.47	GO:0032797	SMN complex
0.47	GO:0034719	SMN-Sm protein complex
0.42	GO:0005829	cytosol
0.41	GO:0005654	nucleoplasm
0.37	GO:0030915	Smc5-Smc6 complex

tr|T1FM25|T1FM25_HELRO
tRNA-splicing ligase RtcB homolog
Search

RTCB

0.88	tRNA-splicing ligase RtcB homolog

0.81	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation
0.50	GO:0001890	placenta development
0.49	GO:0001701	in utero embryonic development
0.43	GO:2000237	positive regulation of tRNA processing
0.34	GO:0006281	DNA repair

0.85	GO:0003972	RNA ligase (ATP) activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0046872	metal ion binding
0.51	GO:0017166	vinculin binding
0.35	GO:0008289	lipid binding
0.34	GO:0008094	DNA-dependent ATPase activity
0.34	GO:0003676	nucleic acid binding

0.85	GO:0072669	tRNA-splicing ligase complex
0.46	GO:0005635	nuclear envelope
0.45	GO:0005789	endoplasmic reticulum membrane
0.44	GO:0005654	nucleoplasm
0.44	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.85

EC:6.5.1.3

GO:0003972

tr|T1FM26|T1FM26_HELRO
Uncharacterized protein
Search

tr|T1FM27|T1FM27_HELRO
Uncharacterized protein
Search

P4HA2

0.82	Prolyl 4-hydroxylase subunit alpha 2

0.81	GO:0019511	peptidyl-proline hydroxylation
0.51	GO:0055114	oxidation-reduction process
0.37	GO:0019471	4-hydroxyproline metabolic process
0.33	GO:0006091	generation of precursor metabolites and energy

0.82	GO:0004656	procollagen-proline 4-dioxygenase activity
0.76	GO:0031418	L-ascorbic acid binding
0.72	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.61	GO:0005506	iron ion binding
0.34	GO:0005515	protein binding
0.33	GO:0009055	electron transfer activity

0.68	GO:0005783	endoplasmic reticulum
0.48	GO:0005654	nucleoplasm
0.47	GO:0005829	cytosol
0.35	GO:1990204	oxidoreductase complex
0.34	GO:0005581	collagen trimer

0.82	EC:1.14.11.2	GO:0004656
0.82	KEGG:R03219	GO:0004656

tr|T1FM28|T1FM28_HELRO
Uncharacterized protein
Search

0.22	Universal stress protein Slr1101

0.62

GO:0006950

response to stress

0.36

GO:0005737

cytoplasm

tr|T1FM29|T1FM29_HELRO
Uncharacterized protein
Search

0.79	Cell number regulator 1

0.41	GO:0007166	cell surface receptor signaling pathway
0.38	GO:0070588	calcium ion transmembrane transport
0.37	GO:0007638	mechanosensory behavior
0.37	GO:0007231	osmosensory signaling pathway
0.37	GO:0048528	post-embryonic root development
0.37	GO:0007186	G-protein coupled receptor signaling pathway
0.36	GO:0033500	carbohydrate homeostasis
0.35	GO:0019752	carboxylic acid metabolic process
0.34	GO:0044267	cellular protein metabolic process
0.34	GO:0008610	lipid biosynthetic process

0.40	GO:0004871	signal transducer activity
0.38	GO:0005262	calcium channel activity
0.37	GO:0099600	transmembrane receptor activity
0.35	GO:0016831	carboxy-lyase activity
0.35	GO:0030170	pyridoxal phosphate binding
0.35	GO:0004831	tyrosine-tRNA ligase activity
0.35	GO:0016790	thiolester hydrolase activity
0.34	GO:0004672	protein kinase activity
0.34	GO:0005524	ATP binding
0.33	GO:0003723	RNA binding

0.35	GO:0005887	integral component of plasma membrane
0.32	GO:0005737	cytoplasm

0.35	EC:4.1.1	GO:0016831
0.35	KEGG:R02918	GO:0004831

tr|T1FM30|T1FM30_HELRO
Uncharacterized protein
Search

tr|T1FM31|T1FM31_HELRO
Uncharacterized protein
Search

NFYC

0.84	Nuclear transcription factor Y subunit gamma

0.57	GO:0006351	transcription, DNA-templated
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.44	GO:0051254	positive regulation of RNA metabolic process
0.44	GO:0010557	positive regulation of macromolecule biosynthetic process
0.44	GO:0031328	positive regulation of cellular biosynthetic process
0.35	GO:0045540	regulation of cholesterol biosynthetic process
0.34	GO:0060041	retina development in camera-type eye
0.33	GO:0006457	protein folding

0.74	GO:0046982	protein heterodimerization activity
0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0003677	DNA binding
0.47	GO:0001067	regulatory region nucleic acid binding
0.36	GO:0008134	transcription factor binding
0.34	GO:0003713	transcription coactivator activity
0.33	GO:0016779	nucleotidyltransferase activity

0.83	GO:0016602	CCAAT-binding factor complex
0.45	GO:0032993	protein-DNA complex
0.45	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:2.7.7

GO:0016779

tr|T1FM32|T1FM32_HELRO
Uncharacterized protein
Search

WDR48

0.92	WD repeat-containing protein 48

0.85	GO:1902525	regulation of protein monoubiquitination
0.84	GO:0072520	seminiferous tubule development
0.79	GO:0035264	multicellular organism growth
0.78	GO:0050679	positive regulation of epithelial cell proliferation
0.78	GO:0043588	skin development
0.77	GO:0007338	single fertilization
0.77	GO:0048705	skeletal system morphogenesis
0.75	GO:0007283	spermatogenesis
0.75	GO:0048568	embryonic organ development
0.73	GO:0016579	protein deubiquitination

0.38	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.38	GO:0016905	myosin heavy chain kinase activity
0.37	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.36	GO:0005515	protein binding
0.35	GO:0016887	ATPase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.59	GO:0005634	nucleus
0.52	GO:0005770	late endosome
0.51	GO:0005764	lysosome
0.36	GO:0043233	organelle lumen
0.35	GO:0044446	intracellular organelle part

0.38

GO:0036459

tr|T1FM33|T1FM33_HELRO
Uncharacterized protein
Search

ABHD12

0.92	Abhydrolase domain containing 12

0.55	GO:0052651	monoacylglycerol catabolic process
0.53	GO:0006660	phosphatidylserine catabolic process
0.52	GO:0010996	response to auditory stimulus
0.51	GO:0007628	adult walking behavior
0.51	GO:0002084	protein depalmitoylation
0.34	GO:0046907	intracellular transport
0.32	GO:0006508	proteolysis
0.32	GO:0006351	transcription, DNA-templated

0.72	GO:0047372	acylglycerol lipase activity
0.51	GO:0008474	palmitoyl-(protein) hydrolase activity
0.50	GO:0004622	lysophospholipase activity
0.33	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.33	GO:0017171	serine hydrolase activity
0.32	GO:0070011	peptidase activity, acting on L-amino acid peptides
0.32	GO:0003677	DNA binding

0.52	GO:0032839	dendrite cytoplasm
0.51	GO:0032281	AMPA glutamate receptor complex
0.33	GO:0005739	mitochondrion

0.72

EC:3.1.1.23

GO:0047372

tr|T1FM34|T1FM34_HELRO
Profilin
Search

0.58

Profilin

0.54

GO:0042989

sequestering of actin monomers

0.74

GO:0003779

actin binding

0.67	GO:0005856	cytoskeleton
0.48	GO:0005938	cell cortex

tr|T1FM35|T1FM35_HELRO
Uncharacterized protein
Search

UAP1

0.83	UDP-N-acetylhexosamine pyrophosphorylase

0.45	GO:0006047	UDP-N-acetylglucosamine metabolic process
0.44	GO:0046349	amino sugar biosynthetic process
0.43	GO:0009226	nucleotide-sugar biosynthetic process
0.36	GO:0016310	phosphorylation
0.35	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.35	GO:0018212	peptidyl-tyrosine modification
0.34	GO:0038065	collagen-activated signaling pathway
0.32	GO:0055114	oxidation-reduction process

0.75	GO:0070569	uridylyltransferase activity
0.46	GO:0042802	identical protein binding
0.36	GO:0016301	kinase activity
0.35	GO:0030246	carbohydrate binding
0.34	GO:0038064	collagen receptor activity
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.33	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.33	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding

0.46	GO:0005829	cytosol
0.45	GO:0005654	nucleoplasm
0.40	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.34

GO:0032440

tr|T1FM36|T1FM36_HELRO
Uncharacterized protein
Search

RPL31

0.66	Ribosomal protein L31

0.57	GO:0043043	peptide biosynthetic process
0.53	GO:0044267	cellular protein metabolic process
0.51	GO:0010467	gene expression
0.50	GO:0009059	macromolecule biosynthetic process
0.33	GO:0006298	mismatch repair
0.33	GO:0090305	nucleic acid phosphodiester bond hydrolysis

0.60	GO:0003735	structural constituent of ribosome
0.33	GO:0005515	protein binding
0.33	GO:0004519	endonuclease activity
0.33	GO:0003723	RNA binding

0.58	GO:0005840	ribosome
0.41	GO:0044445	cytosolic part
0.38	GO:0005844	polysome
0.37	GO:0044446	intracellular organelle part
0.34	GO:0005791	rough endoplasmic reticulum
0.34	GO:0005925	focal adhesion
0.34	GO:0070062	extracellular exosome
0.34	GO:0098562	cytoplasmic side of membrane
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0098588	bounding membrane of organelle

tr|T1FM37|T1FM37_HELRO
DNA-directed RNA polymerase subunit
Search

0.48	DNA-directed RNA polymerases III 12.5 kDa polypeptide

0.81	GO:0006379	mRNA cleavage
0.58	GO:0097659	nucleic acid-templated transcription
0.54	GO:0010467	gene expression
0.53	GO:0034645	cellular macromolecule biosynthetic process
0.48	GO:1903506	regulation of nucleic acid-templated transcription
0.48	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.48	GO:0010468	regulation of gene expression

0.70	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.63	GO:0008270	zinc ion binding
0.51	GO:0003676	nucleic acid binding

0.70

GO:0003899

tr|T1FM38|T1FM38_HELRO
Uncharacterized protein
Search

0.52	Phosphoribosyl pyrophosphate synthetase

0.66	GO:0009116	nucleoside metabolic process
0.51	GO:0009165	nucleotide biosynthetic process
0.47	GO:0016310	phosphorylation
0.34	GO:0006488	dolichol-linked oligosaccharide biosynthetic process

0.61	GO:0004749	ribose phosphate diphosphokinase activity
0.52	GO:0000287	magnesium ion binding
0.48	GO:0016301	kinase activity
0.35	GO:0016757	transferase activity, transferring glycosyl groups
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.41	GO:0055044	symplast
0.40	GO:0005911	cell-cell junction
0.38	GO:0005829	cytosol
0.36	GO:0005886	plasma membrane
0.34	GO:0009507	chloroplast
0.33	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

0.61	EC:2.7.6.1	GO:0004749
0.61	KEGG:R01049	GO:0004749

tr|T1FM39|T1FM39_HELRO
Transmembrane 9 superfamily member
Search

TM9SF3

0.53	Transmembrane 9 superfamily member

0.34

GO:0035335

peptidyl-tyrosine dephosphorylation

0.34

GO:0004725

protein tyrosine phosphatase activity

0.34	GO:0070382	exocytic vesicle
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:3.1.3.48

GO:0004725

tr|T1FM40|T1FM40_HELRO
Uncharacterized protein
Search

0.75	Rho guanine dissociation factor

0.69	GO:0050790	regulation of catalytic activity
0.37	GO:0007264	small GTPase mediated signal transduction
0.36	GO:0006907	pinocytosis
0.36	GO:0035023	regulation of Rho protein signal transduction
0.36	GO:0030036	actin cytoskeleton organization
0.36	GO:0000281	mitotic cytokinesis
0.35	GO:0000302	response to reactive oxygen species
0.35	GO:1901164	negative regulation of trophoblast cell migration
0.35	GO:0033043	regulation of organelle organization
0.34	GO:0032970	regulation of actin filament-based process

0.85	GO:0005094	Rho GDP-dissociation inhibitor activity
0.34	GO:0048365	Rac GTPase binding
0.34	GO:0003924	GTPase activity
0.34	GO:0103025	alpha-amylase activity (releasing maltohexaose)
0.34	GO:0004556	alpha-amylase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.33	GO:0016829	lyase activity
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.49	GO:0005737	cytoplasm
0.34	GO:0005934	cellular bud tip
0.34	GO:0005935	cellular bud neck
0.30	GO:0016020	membrane

0.34

EC:3.2.1.1

GO:0004556

tr|T1FM41|T1FM41_HELRO
Uncharacterized protein
Search

SAE1

0.93	SUMO-activating enzyme subunit 1

0.57	GO:0036211	protein modification process
0.53	GO:0044267	cellular protein metabolic process
0.51	GO:1903955	positive regulation of protein targeting to mitochondrion
0.45	GO:0061484	hematopoietic stem cell homeostasis
0.44	GO:0060216	definitive hemopoiesis
0.34	GO:0043085	positive regulation of catalytic activity

0.76	GO:0008641	ubiquitin-like modifier activating enzyme activity
0.53	GO:0044388	small protein activating enzyme binding
0.53	GO:0043008	ATP-dependent protein binding
0.51	GO:0008022	protein C-terminus binding
0.47	GO:0046982	protein heterodimerization activity
0.34	GO:0008047	enzyme activator activity

0.55	GO:0031510	SUMO activating enzyme complex
0.36	GO:0005737	cytoplasm
0.34	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1FM42|T1FM42_HELRO
Uncharacterized protein
Search

TIPRL

0.83	TOR signalling pathway protein TipA

0.68	GO:0043009	chordate embryonic development
0.67	GO:0043066	negative regulation of apoptotic process
0.45	GO:0007165	signal transduction
0.38	GO:0035335	peptidyl-tyrosine dephosphorylation
0.38	GO:0009968	negative regulation of signal transduction
0.36	GO:0042254	ribosome biogenesis

0.39	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.38	GO:0004725	protein tyrosine phosphatase activity
0.36	GO:0005515	protein binding

0.38	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

0.39

EC:3.1.3

GO:0008138

tr|T1FM43|T1FM43_HELRO
Uncharacterized protein
Search

GFOD2

0.37	Glucose-fructose oxidoreductase domain-containing protein 1

0.52	GO:0055114	oxidation-reduction process
0.38	GO:0030198	extracellular matrix organization
0.34	GO:0006309	apoptotic DNA fragmentation
0.32	GO:0006520	cellular amino acid metabolic process
0.32	GO:0009058	biosynthetic process

0.53	GO:0016491	oxidoreductase activity
0.34	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity
0.34	GO:0070546	L-phenylalanine aminotransferase activity
0.33	GO:0030170	pyridoxal phosphate binding
0.32	GO:0016787	hydrolase activity

0.38	GO:0005578	proteinaceous extracellular matrix
0.33	GO:0005634	nucleus
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.53	EC:1	GO:0016491
0.34	KEGG:R00355	GO:0004069

tr|T1FM44|T1FM44_HELRO
Uncharacterized protein
Search

HAT1

0.72	Histone acetyltransferase type B catalytic subunit

0.83	GO:0006348	chromatin silencing at telomere
0.78	GO:0016573	histone acetylation
0.51	GO:0006336	DNA replication-independent nucleosome assembly
0.51	GO:0006335	DNA replication-dependent nucleosome assembly
0.39	GO:0031055	chromatin remodeling at centromere
0.39	GO:0061641	CENP-A containing chromatin organization
0.38	GO:0043486	histone exchange
0.38	GO:0034508	centromere complex assembly
0.36	GO:0007584	response to nutrient
0.34	GO:0032392	DNA geometric change

0.80	GO:0004402	histone acetyltransferase activity
0.80	GO:0042393	histone binding
0.34	GO:0004003	ATP-dependent DNA helicase activity
0.33	GO:0070006	metalloaminopeptidase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0003677	DNA binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0046872	metal ion binding

0.80	GO:0000781	chromosome, telomeric region
0.61	GO:0005634	nucleus
0.47	GO:0000785	chromatin
0.45	GO:0031974	membrane-enclosed lumen
0.41	GO:0043234	protein complex
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.80

GO:0004402

tr|T1FM45|T1FM45_HELRO
Uncharacterized protein
Search

tr|T1FM46|T1FM46_HELRO
Uncharacterized protein
Search

0.72	DNA-directed RNA polymerase III subunit RPC6

0.81	GO:0006383	transcription by RNA polymerase III
0.47	GO:0060041	retina development in camera-type eye
0.43	GO:0032728	positive regulation of interferon-beta production
0.41	GO:0045089	positive regulation of innate immune response
0.36	GO:0009304	tRNA transcription

0.68	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.39	GO:0003690	double-stranded DNA binding

0.81	GO:0005666	DNA-directed RNA polymerase III complex
0.34	GO:0005739	mitochondrion
0.33	GO:0005829	cytosol

0.68

GO:0003899

tr|T1FM47|T1FM47_HELRO
Uncharacterized protein
Search

0.51	Glutathione S-transferase 1

0.61	GO:0004364	glutathione transferase activity
0.45	GO:0005212	structural constituent of eye lens

0.30

GO:0044425

membrane part

0.61

EC:2.5.1.18

GO:0004364

tr|T1FM48|T1FM48_HELRO
Uncharacterized protein
Search

0.20	Glutathione-S-transferase

0.51

GO:0016740

transferase activity

0.51

GO:0016740

tr|T1FM49|T1FM49_HELRO
Uncharacterized protein
Search

LANCL1

0.88	LanC lantibiotic synthetase component C-like 1 (Bacterial)

0.49

GO:0007165

signal transduction

0.85	GO:0050750	low-density lipoprotein particle receptor binding
0.84	GO:0043295	glutathione binding
0.78	GO:0017124	SH3 domain binding
0.62	GO:0008270	zinc ion binding

0.46

GO:0005886

plasma membrane

tr|T1FM50|T1FM50_HELRO
Inhibitor of growth protein
Search

ING4

0.71	Inhibitor of growth protein 4

0.78	GO:0008285	negative regulation of cell proliferation
0.77	GO:0016573	histone acetylation
0.66	GO:0043065	positive regulation of apoptotic process
0.49	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
0.47	GO:0007050	cell cycle arrest
0.46	GO:0045926	negative regulation of growth
0.45	GO:0006915	apoptotic process
0.43	GO:0045892	negative regulation of transcription, DNA-templated
0.43	GO:2001233	regulation of apoptotic signaling pathway
0.41	GO:0006260	DNA replication

0.68	GO:0140034	methylation-dependent protein binding
0.65	GO:0042393	histone binding
0.53	GO:0046872	metal ion binding
0.46	GO:0003713	transcription coactivator activity
0.41	GO:0003682	chromatin binding
0.34	GO:0050660	flavin adenine dinucleotide binding
0.34	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors

0.70	GO:0070776	MOZ/MORF histone acetyltransferase complex
0.45	GO:0045111	intermediate filament cytoskeleton
0.42	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:1.1

GO:0016614

tr|T1FM51|T1FM51_HELRO
Uncharacterized protein
Search

0.35	Peptidylprolyl isomerase

0.65	GO:0000413	protein peptidyl-prolyl isomerization
0.42	GO:0048366	leaf development
0.37	GO:0033674	positive regulation of kinase activity
0.37	GO:0051716	cellular response to stimulus
0.37	GO:0045859	regulation of protein kinase activity
0.37	GO:0007601	visual perception
0.37	GO:0016126	sterol biosynthetic process
0.37	GO:0023052	signaling
0.37	GO:0007154	cell communication
0.36	GO:0006417	regulation of translation

0.66	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.41	GO:0005516	calmodulin binding
0.38	GO:0019887	protein kinase regulator activity
0.37	GO:0019901	protein kinase binding
0.37	GO:0004421	hydroxymethylglutaryl-CoA synthase activity
0.37	GO:0043022	ribosome binding
0.37	GO:0005528	FK506 binding
0.36	GO:0031072	heat shock protein binding
0.35	GO:0016301	kinase activity
0.34	GO:0008146	sulfotransferase activity

0.36	GO:0005886	plasma membrane
0.33	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

0.66	EC:5.2.1.8	GO:0003755
0.37	KEGG:R01978	GO:0004421

tr|T1FM52|T1FM52_HELRO
Uncharacterized protein
Search

0.41	Enolase (inferred by orthology to a C. elegans protein)

0.71	GO:0006757	ATP generation from ADP
0.69	GO:0006090	pyruvate metabolic process
0.68	GO:0016052	carbohydrate catabolic process
0.67	GO:0046496	nicotinamide nucleotide metabolic process
0.43	GO:1903297	regulation of hypoxia-induced intrinsic apoptotic signaling pathway
0.43	GO:0010756	positive regulation of plasminogen activation
0.43	GO:2001171	positive regulation of ATP biosynthetic process
0.43	GO:1900038	negative regulation of cellular response to hypoxia
0.42	GO:0045933	positive regulation of muscle contraction
0.41	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway

0.78	GO:0004634	phosphopyruvate hydratase activity
0.64	GO:0000287	magnesium ion binding
0.41	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.41	GO:0045296	cadherin binding
0.40	GO:0042803	protein homodimerization activity
0.40	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.39	GO:0051020	GTPase binding
0.35	GO:0046982	protein heterodimerization activity
0.34	GO:0005212	structural constituent of eye lens
0.32	GO:0003723	RNA binding

0.77	GO:0000015	phosphopyruvate hydratase complex
0.43	GO:0001917	photoreceptor inner segment
0.43	GO:0043204	perikaryon
0.42	GO:0043209	myelin sheath
0.41	GO:0005886	plasma membrane
0.41	GO:0099738	cell cortex region
0.39	GO:0009986	cell surface
0.35	GO:0070062	extracellular exosome
0.34	GO:0031430	M band
0.34	GO:0000145	exocyst

0.78

EC:4.2.1.11

GO:0004634

tr|T1FM53|T1FM53_HELRO
Uncharacterized protein
Search

ADPRH

0.97	ADP-ribosylarginine hydrolase

0.84	GO:0051725	protein de-ADP-ribosylation
0.48	GO:0031338	regulation of vesicle fusion
0.47	GO:0090630	activation of GTPase activity
0.43	GO:0006886	intracellular protein transport
0.34	GO:0006629	lipid metabolic process

0.85	GO:0003875	ADP-ribosylarginine hydrolase activity
0.61	GO:0000287	magnesium ion binding
0.53	GO:0030955	potassium ion binding
0.46	GO:0017137	Rab GTPase binding
0.45	GO:0005096	GTPase activator activity
0.35	GO:0052689	carboxylic ester hydrolase activity

0.42	GO:0012505	endomembrane system
0.35	GO:0005622	intracellular
0.34	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.85	EC:3.2.2.19	GO:0003875
0.35	KEGG:R00630	GO:0052689

tr|T1FM54|T1FM54_HELRO
Uncharacterized protein
Search

CCT5

0.77	T-complex protein subunit epsilon

0.69	GO:0006457	protein folding
0.55	GO:1904869	regulation of protein localization to Cajal body
0.55	GO:1904851	positive regulation of establishment of protein localization to telomere
0.54	GO:1904874	positive regulation of telomerase RNA localization to Cajal body
0.53	GO:0032212	positive regulation of telomere maintenance via telomerase
0.52	GO:0007339	binding of sperm to zona pellucida
0.52	GO:1900182	positive regulation of protein localization to nucleus
0.50	GO:0050821	protein stabilization
0.50	GO:1901998	toxin transport
0.49	GO:0009615	response to virus

0.71	GO:0051082	unfolded protein binding
0.55	GO:0031681	G-protein beta-subunit binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0048487	beta-tubulin binding
0.52	GO:0003730	mRNA 3'-UTR binding
0.51	GO:0048027	mRNA 5'-UTR binding
0.49	GO:0044183	protein binding involved in protein folding

0.57	GO:0005832	chaperonin-containing T-complex
0.53	GO:0002199	zona pellucida receptor complex
0.50	GO:0043209	myelin sheath
0.50	GO:0044297	cell body
0.50	GO:0005813	centrosome
0.49	GO:0005730	nucleolus
0.48	GO:0005874	microtubule
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

tr|T1FM55|T1FM55_HELRO
Uncharacterized protein
Search

0.84	GO:0016240	autophagosome membrane docking
0.72	GO:0060271	cilium assembly
0.66	GO:0031629	synaptic vesicle fusion to presynaptic active zone membrane
0.65	GO:0016082	synaptic vesicle priming
0.60	GO:0072114	pronephros morphogenesis
0.58	GO:0048730	epidermis morphogenesis
0.44	GO:0015031	protein transport
0.41	GO:0043312	neutrophil degranulation
0.40	GO:0006903	vesicle targeting

0.62	GO:0019905	syntaxin binding
0.60	GO:0005484	SNAP receptor activity
0.36	GO:0046983	protein dimerization activity
0.34	GO:0003677	DNA binding

0.84	GO:0020018	ciliary pocket membrane
0.77	GO:0031201	SNARE complex
0.72	GO:0005776	autophagosome
0.70	GO:0005813	centrosome
0.64	GO:0005654	nucleoplasm
0.63	GO:0005829	cytosol
0.59	GO:0098793	presynapse
0.49	GO:0005774	vacuolar membrane
0.48	GO:0000139	Golgi membrane
0.47	GO:0031410	cytoplasmic vesicle

tr|T1FM56|T1FM56_HELRO
Uncharacterized protein
Search

VAPB

0.56	Vamp vesicle associated membrane protein associated protein a

0.58	GO:0030968	endoplasmic reticulum unfolded protein response
0.56	GO:0006874	cellular calcium ion homeostasis
0.48	GO:0051641	cellular localization
0.46	GO:0032075	positive regulation of nuclease activity
0.45	GO:0045070	positive regulation of viral genome replication
0.44	GO:0007029	endoplasmic reticulum organization
0.44	GO:0048194	Golgi vesicle budding
0.44	GO:0008104	protein localization
0.43	GO:0045860	positive regulation of protein kinase activity
0.40	GO:0019048	modulation by virus of host morphology or physiology

0.58	GO:0033149	FFAT motif binding
0.44	GO:0048487	beta-tubulin binding
0.44	GO:0045296	cadherin binding
0.42	GO:0042803	protein homodimerization activity
0.42	GO:0008017	microtubule binding
0.42	GO:0046982	protein heterodimerization activity
0.41	GO:0019899	enzyme binding
0.33	GO:0004004	ATP-dependent RNA helicase activity
0.32	GO:0035091	phosphatidylinositol binding
0.32	GO:0030554	adenyl nucleotide binding

0.72	GO:0005789	endoplasmic reticulum membrane
0.51	GO:0005794	Golgi apparatus
0.44	GO:0005856	cytoskeleton
0.41	GO:0098588	bounding membrane of organelle
0.38	GO:0043005	neuron projection
0.37	GO:0005615	extracellular space
0.35	GO:0005886	plasma membrane
0.35	GO:0045202	synapse
0.34	GO:0070382	exocytic vesicle
0.34	GO:0070971	endoplasmic reticulum exit site

tr|T1FM57|T1FM57_HELRO
Mitochondrial fission 1 protein
Search

0.61	Mitochondrial fission 1 protein (Fragment)

0.84

GO:0000266

mitochondrial fission

0.75	GO:0005741	mitochondrial outer membrane
0.30	GO:0044425	membrane part

tr|T1FM58|T1FM58_HELRO
Uncharacterized protein
Search

0.53	GO:0055114	oxidation-reduction process
0.37	GO:0044550	secondary metabolite biosynthetic process
0.34	GO:0046246	terpene biosynthetic process
0.33	GO:0070932	histone H3 deacetylation
0.33	GO:0045859	regulation of protein kinase activity
0.32	GO:0006351	transcription, DNA-templated
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression
0.32	GO:0055085	transmembrane transport

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.63	GO:0020037	heme binding
0.63	GO:0004497	monooxygenase activity
0.63	GO:0005506	iron ion binding
0.33	GO:0032041	NAD-dependent histone deacetylase activity (H3-K14 specific)
0.33	GO:0046982	protein heterodimerization activity
0.33	GO:0019887	protein kinase regulator activity
0.32	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity
0.32	GO:0070546	L-phenylalanine aminotransferase activity
0.32	GO:0042626	ATPase activity, coupled to transmembrane movement of substances

0.33	GO:0000786	nucleosome
0.33	GO:0005634	nucleus
0.33	GO:0005956	protein kinase CK2 complex
0.30	GO:0031224	intrinsic component of membrane

0.68	EC:1.14	GO:0016705
0.32	KEGG:R00355	GO:0004069

tr|T1FM59|T1FM59_HELRO
Uncharacterized protein
Search

SLC25A10

0.58	Mitochondrial substrate solute carrier

0.47	GO:0006839	mitochondrial transport
0.46	GO:1902356	oxaloacetate(2-) transmembrane transport
0.46	GO:0071422	succinate transmembrane transport
0.45	GO:0071423	malate transmembrane transport
0.44	GO:0015709	thiosulfate transport
0.42	GO:0035435	phosphate ion transmembrane transport
0.42	GO:1902358	sulfate transmembrane transport
0.35	GO:0070221	sulfide oxidation, using sulfide:quinone oxidoreductase
0.33	GO:0019319	hexose biosynthetic process
0.33	GO:0006006	glucose metabolic process

0.46	GO:0015131	oxaloacetate transmembrane transporter activity
0.46	GO:0015141	succinate transmembrane transporter activity
0.45	GO:0015140	malate transmembrane transporter activity
0.44	GO:0015117	thiosulfate transmembrane transporter activity
0.42	GO:0015116	sulfate transmembrane transporter activity
0.41	GO:0015291	secondary active transmembrane transporter activity
0.33	GO:0015114	phosphate ion transmembrane transporter activity
0.33	GO:0005515	protein binding
0.32	GO:0003676	nucleic acid binding

0.42	GO:0005739	mitochondrion
0.41	GO:0031967	organelle envelope
0.41	GO:0031090	organelle membrane
0.36	GO:0005654	nucleoplasm
0.36	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1FM60|T1FM60_HELRO
Uncharacterized protein
Search

0.50	Ubiquitin conjugating enzyme

0.40	GO:0016567	protein ubiquitination
0.39	GO:0006511	ubiquitin-dependent protein catabolic process
0.35	GO:0010498	proteasomal protein catabolic process
0.35	GO:0035103	sterol regulatory element binding protein cleavage
0.35	GO:0031399	regulation of protein modification process
0.34	GO:0010559	regulation of glycoprotein biosynthetic process
0.34	GO:0045676	regulation of R7 cell differentiation
0.34	GO:0048132	female germ-line stem cell asymmetric division
0.34	GO:0045842	positive regulation of mitotic metaphase/anaphase transition
0.34	GO:0016322	neuron remodeling

0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0061631	ubiquitin conjugating enzyme activity
0.39	GO:0016874	ligase activity
0.38	GO:0031625	ubiquitin protein ligase binding
0.33	GO:0061630	ubiquitin protein ligase activity

0.35	GO:0043224	nuclear SCF ubiquitin ligase complex
0.33	GO:0005694	chromosome
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.39

GO:0016874

tr|T1FM61|T1FM61_HELRO
Uncharacterized protein
Search

SNU13

0.97	Small nuclear ribonucleoprotein 13

0.67	GO:0000492	box C/D snoRNP assembly
0.67	GO:0042254	ribosome biogenesis
0.63	GO:0007338	single fertilization
0.51	GO:0000398	mRNA splicing, via spliceosome
0.48	GO:0016072	rRNA metabolic process
0.46	GO:0034470	ncRNA processing
0.44	GO:0043043	peptide biosynthetic process
0.42	GO:0044267	cellular protein metabolic process
0.40	GO:0034645	cellular macromolecule biosynthetic process
0.39	GO:0061053	somite development

0.70	GO:0030622	U4atac snRNA binding
0.68	GO:0034512	box C/D snoRNA binding
0.68	GO:0030621	U4 snRNA binding
0.67	GO:0034511	U3 snoRNA binding
0.65	GO:0051117	ATPase binding

0.73	GO:0005730	nucleolus
0.66	GO:0005732	small nucleolar ribonucleoprotein complex
0.55	GO:0071011	precatalytic spliceosome
0.53	GO:0046540	U4/U6 x U5 tri-snRNP complex
0.53	GO:0022625	cytosolic large ribosomal subunit
0.52	GO:0032040	small-subunit processome
0.49	GO:0043234	protein complex
0.37	GO:0019013	viral nucleocapsid

tr|T1FM62|T1FM62_HELRO
Uncharacterized protein
Search

LMAN2

0.81	Lectin mannose-binding 2

0.51	GO:0050766	positive regulation of phagocytosis
0.49	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.38	GO:0048881	mechanosensory lateral line system development
0.36	GO:0001172	transcription, RNA-templated
0.36	GO:0019079	viral genome replication
0.35	GO:0015031	protein transport
0.34	GO:0016310	phosphorylation
0.33	GO:0007165	signal transduction
0.33	GO:0036211	protein modification process
0.33	GO:0044267	cellular protein metabolic process

0.51	GO:0005537	mannose binding
0.48	GO:0031072	heat shock protein binding
0.36	GO:0003968	RNA-directed 5'-3' RNA polymerase activity
0.36	GO:0004703	G-protein coupled receptor kinase activity
0.33	GO:0046872	metal ion binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0003723	RNA binding

0.50	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.47	GO:0009986	cell surface
0.46	GO:0005615	extracellular space
0.46	GO:0005794	Golgi apparatus
0.44	GO:0005887	integral component of plasma membrane
0.36	GO:0031984	organelle subcompartment
0.35	GO:0031982	vesicle
0.35	GO:0043230	extracellular organelle
0.35	GO:0098588	bounding membrane of organelle
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network

0.36

EC:2.7.7.48

GO:0003968

tr|T1FM63|T1FM63_HELRO
Uncharacterized protein
Search

SYF2

0.81	Pre-mRNA-splicing factor syf2

0.67	GO:0007095	mitotic G2 DNA damage checkpoint
0.64	GO:0007369	gastrulation
0.63	GO:0001701	in utero embryonic development
0.62	GO:0048568	embryonic organ development
0.50	GO:0008380	RNA splicing
0.48	GO:0006397	mRNA processing
0.45	GO:0008284	positive regulation of cell proliferation
0.39	GO:0072488	ammonium transmembrane transport

0.39	GO:0008519	ammonium transmembrane transporter activity
0.37	GO:0003723	RNA binding
0.36	GO:0005515	protein binding
0.36	GO:0016853	isomerase activity

0.79	GO:0071013	catalytic step 2 spliceosome
0.71	GO:0000974	Prp19 complex
0.70	GO:0071014	post-mRNA release spliceosomal complex
0.67	GO:0005684	U2-type spliceosomal complex
0.67	GO:0016607	nuclear speck
0.30	GO:0016020	membrane

0.36

EC:5

GO:0016853

tr|T1FM64|T1FM64_HELRO
Uncharacterized protein
Search

tr|T1FM65|T1FM65_HELRO
Protein Wnt
Search

tr|T1FM66|T1FM66_HELRO
Uncharacterized protein
Search

RAB14

0.87	Putative rab subfamily protein of small gtpase

0.85	GO:0090382	phagosome maturation
0.85	GO:0006895	Golgi to endosome transport
0.84	GO:0032456	endocytic recycling
0.77	GO:0042742	defense response to bacterium
0.51	GO:0008543	fibroblast growth factor receptor signaling pathway
0.50	GO:0032879	regulation of localization
0.48	GO:0009790	embryo development
0.43	GO:0051128	regulation of cellular component organization
0.36	GO:0015031	protein transport
0.35	GO:0043312	neutrophil degranulation

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0031489	myosin V binding
0.34	GO:0004767	sphingomyelin phosphodiesterase activity
0.34	GO:0004866	endopeptidase inhibitor activity
0.32	GO:0016874	ligase activity

0.83	GO:0045335	phagocytic vesicle
0.82	GO:0055037	recycling endosome
0.79	GO:0005802	trans-Golgi network
0.68	GO:0005829	cytosol
0.39	GO:0031901	early endosome membrane
0.38	GO:0000139	Golgi membrane
0.36	GO:0030659	cytoplasmic vesicle membrane
0.36	GO:0030140	trans-Golgi network transport vesicle
0.36	GO:0005791	rough endoplasmic reticulum
0.36	GO:0005765	lysosomal membrane

0.34	EC:3.1.4.12	GO:0004767
0.34	KEGG:R02541	GO:0004767

tr|T1FM67|T1FM67_HELRO
Uncharacterized protein
Search

0.45	Selenophosphate synthetase

0.77	GO:0016260	selenocysteine biosynthetic process
0.57	GO:0016310	phosphorylation
0.38	GO:2000378	negative regulation of reactive oxygen species metabolic process
0.37	GO:0007444	imaginal disc development
0.37	GO:0008283	cell proliferation
0.37	GO:0008284	positive regulation of cell proliferation
0.36	GO:0007005	mitochondrion organization
0.36	GO:0006541	glutamine metabolic process
0.35	GO:0046041	ITP metabolic process
0.34	GO:0006172	ADP biosynthetic process

0.81	GO:0004756	selenide, water dikinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0042802	identical protein binding
0.35	GO:0046982	protein heterodimerization activity
0.35	GO:0046899	nucleoside triphosphate adenylate kinase activity
0.34	GO:0004017	adenylate kinase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding

0.35	GO:0031965	nuclear membrane
0.34	GO:0005759	mitochondrial matrix
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.81	EC:2.7.9.3	GO:0004756
0.81	KEGG:R03595	GO:0004756

tr|T1FM68|T1FM68_HELRO
Tetraspanin
Search

0.58	Tetraspanin

0.51	GO:0045747	positive regulation of Notch signaling pathway
0.49	GO:0007298	border follicle cell migration
0.41	GO:0072659	protein localization to plasma membrane
0.41	GO:0007399	nervous system development
0.40	GO:0007166	cell surface receptor signaling pathway
0.38	GO:0051604	protein maturation
0.37	GO:1901046	positive regulation of oviposition
0.36	GO:0040026	positive regulation of vulval development
0.36	GO:0042661	regulation of mesodermal cell fate specification
0.36	GO:0045138	nematode male tail tip morphogenesis

0.39	GO:0019899	enzyme binding
0.36	GO:0003735	structural constituent of ribosome

0.39	GO:0005887	integral component of plasma membrane
0.35	GO:0005840	ribosome
0.35	GO:0030659	cytoplasmic vesicle membrane
0.34	GO:0097197	tetraspanin-enriched microdomain
0.33	GO:0009986	cell surface

tr|T1FM69|T1FM69_HELRO
Uncharacterized protein
Search

0.67	V-type proton ATPase subunit d

0.76	GO:0015991	ATP hydrolysis coupled proton transport
0.51	GO:0036295	cellular response to increased oxygen levels
0.50	GO:0007035	vacuolar acidification
0.46	GO:0006879	cellular iron ion homeostasis
0.44	GO:0007430	terminal branching, open tracheal system
0.44	GO:0007034	vacuolar transport
0.42	GO:0008593	regulation of Notch signaling pathway
0.40	GO:0060271	cilium assembly
0.38	GO:0035675	neuromast hair cell development
0.38	GO:0008057	eye pigment granule organization

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.49	GO:0036442	proton-exporting ATPase activity
0.47	GO:0015662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
0.42	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
0.36	GO:0032403	protein complex binding
0.34	GO:0052654	L-leucine transaminase activity
0.34	GO:0052656	L-isoleucine transaminase activity
0.34	GO:0052655	L-valine transaminase activity

0.79	GO:0033179	proton-transporting V-type ATPase, V0 domain
0.50	GO:0016471	vacuolar proton-transporting V-type ATPase complex
0.49	GO:0005769	early endosome
0.47	GO:0005813	centrosome
0.45	GO:0005765	lysosomal membrane
0.44	GO:0033181	plasma membrane proton-transporting V-type ATPase complex
0.37	GO:0043679	axon terminus
0.37	GO:0008021	synaptic vesicle
0.37	GO:0016324	apical plasma membrane
0.36	GO:0070062	extracellular exosome

0.34	EC:2.6.1.42	GO:0052654
0.34	KEGG:R01090	GO:0052654

tr|T1FM70|T1FM70_HELRO
ATP synthase subunit alpha
Search

0.45	ATP synthase subunit alpha

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.69	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.35	GO:0001937	negative regulation of endothelial cell proliferation
0.35	GO:0043536	positive regulation of blood vessel endothelial cell migration
0.34	GO:0002098	tRNA wobble uridine modification
0.33	GO:0006629	lipid metabolic process

0.71	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0043532	angiostatin binding
0.35	GO:0042288	MHC class I protein binding

0.72	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)
0.34	GO:0043209	myelin sheath
0.34	GO:0008180	COP9 signalosome
0.34	GO:0033588	Elongator holoenzyme complex
0.34	GO:0005753	mitochondrial proton-transporting ATP synthase complex
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1FM71|T1FM71_HELRO
Fascin
Search

0.84

Fascin

0.75	GO:0007015	actin filament organization
0.61	GO:0016477	cell migration
0.52	GO:0007163	establishment or maintenance of cell polarity
0.48	GO:0030035	microspike assembly
0.48	GO:0032534	regulation of microvillus assembly
0.48	GO:0090091	positive regulation of extracellular matrix disassembly
0.47	GO:0071803	positive regulation of podosome assembly
0.47	GO:0010592	positive regulation of lamellipodium assembly
0.47	GO:0009653	anatomical structure morphogenesis
0.47	GO:0051491	positive regulation of filopodium assembly

0.80	GO:0030674	protein binding, bridging
0.78	GO:0051015	actin filament binding
0.45	GO:0045296	cadherin binding
0.37	GO:0008144	drug binding
0.34	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity
0.32	GO:0003723	RNA binding

0.61	GO:0005856	cytoskeleton
0.49	GO:0044393	microspike
0.48	GO:0043005	neuron projection
0.47	GO:0005902	microvillus
0.47	GO:0071437	invadopodium
0.47	GO:0030175	filopodium
0.47	GO:0001726	ruffle
0.46	GO:0031253	cell projection membrane
0.46	GO:0030027	lamellipodium
0.45	GO:0099512	supramolecular fiber

0.34

EC:1.1.1.35

GO:0003857

tr|T1FM72|T1FM72_HELRO
Uncharacterized protein
Search

NAPG

0.91	N-ethylmaleimide-sensitive factor attachment protein, gamma a

0.69	GO:0006886	intracellular protein transport
0.42	GO:0061025	membrane fusion
0.36	GO:0016192	vesicle-mediated transport
0.34	GO:0050821	protein stabilization
0.33	GO:0006461	protein complex assembly

0.49	GO:0005483	soluble NSF attachment protein activity
0.47	GO:0019905	syntaxin binding

0.50	GO:0043209	myelin sheath
0.47	GO:0031201	SNARE complex
0.45	GO:0005774	vacuolar membrane
0.43	GO:0005739	mitochondrion
0.37	GO:0005764	lysosome
0.36	GO:0070062	extracellular exosome

tr|T1FM73|T1FM73_HELRO
Uncharacterized protein
Search

tr|T1FM74|T1FM74_HELRO
Uncharacterized protein
Search

POLB

0.89	DNA polymerase beta

0.66	GO:0071897	DNA biosynthetic process
0.63	GO:0006281	DNA repair
0.56	GO:0071707	immunoglobulin heavy chain V-D-J recombination
0.54	GO:0016446	somatic hypermutation of immunoglobulin genes
0.54	GO:0048535	lymph node development
0.53	GO:0048536	spleen development
0.53	GO:0051402	neuron apoptotic process
0.52	GO:0007435	salivary gland morphogenesis
0.52	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage
0.50	GO:0006954	inflammatory response

0.69	GO:0003887	DNA-directed DNA polymerase activity
0.54	GO:0003677	DNA binding
0.49	GO:0008017	microtubule binding
0.48	GO:0019899	enzyme binding
0.44	GO:0016829	lyase activity
0.35	GO:0046872	metal ion binding

0.60	GO:0005634	nucleus
0.53	GO:0005876	spindle microtubule
0.43	GO:0043234	protein complex
0.39	GO:0005737	cytoplasm
0.35	GO:0043233	organelle lumen
0.34	GO:0000793	condensed chromosome
0.34	GO:0044427	chromosomal part
0.30	GO:0016021	integral component of membrane

0.69

GO:0003887

tr|T1FM75|T1FM75_HELRO
Uncharacterized protein
Search

CANX

0.82

Calnexin

0.69	GO:0006457	protein folding
0.41	GO:0048488	synaptic vesicle endocytosis
0.39	GO:0048916	posterior lateral line development
0.38	GO:0072583	clathrin-dependent endocytosis
0.36	GO:0007339	binding of sperm to zona pellucida
0.36	GO:0007568	aging
0.34	GO:0006461	protein complex assembly

0.71	GO:0051082	unfolded protein binding
0.70	GO:0005509	calcium ion binding
0.37	GO:0034185	apolipoprotein binding
0.37	GO:0035255	ionotropic glutamate receptor binding
0.36	GO:0044183	protein binding involved in protein folding
0.35	GO:0030246	carbohydrate binding
0.33	GO:0005198	structural molecule activity

0.70	GO:0005783	endoplasmic reticulum
0.40	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.39	GO:0031984	organelle subcompartment
0.39	GO:0044233	ER-mitochondrion membrane contact site
0.39	GO:0043209	myelin sheath
0.38	GO:0045202	synapse
0.37	GO:0032839	dendrite cytoplasm
0.36	GO:0042470	melanosome
0.36	GO:0044309	neuron spine
0.36	GO:0043025	neuronal cell body

tr|T1FM76|T1FM76_HELRO
Uncharacterized protein
Search

FAAH2

0.81	fatty-acid amide hydrolase 2-A

0.37	GO:0019369	arachidonic acid metabolic process
0.34	GO:0055114	oxidation-reduction process

0.47	GO:0016787	hydrolase activity
0.41	GO:0016874	ligase activity
0.34	GO:0016740	transferase activity
0.34	GO:0016491	oxidoreductase activity

0.36	GO:0005811	lipid droplet
0.35	GO:0012505	endomembrane system
0.30	GO:0044425	membrane part

0.47

GO:0016787

tr|T1FM77|T1FM77_HELRO
Uncharacterized protein
Search

GTF2F1

0.86	Transcription initiation factor IIF large subunit

0.81	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter
0.79	GO:0006367	transcription initiation from RNA polymerase II promoter
0.45	GO:0009615	response to virus
0.45	GO:0006368	transcription elongation from RNA polymerase II promoter
0.44	GO:0043085	positive regulation of catalytic activity
0.40	GO:0006413	translational initiation
0.35	GO:0042795	snRNA transcription by RNA polymerase II
0.34	GO:0008543	fibroblast growth factor receptor signaling pathway
0.34	GO:0050434	positive regulation of viral transcription
0.34	GO:0000398	mRNA splicing, via spliceosome

0.55	GO:0003677	DNA binding
0.48	GO:0001096	TFIIF-class transcription factor binding
0.48	GO:0019211	phosphatase activator activity
0.48	GO:0019903	protein phosphatase binding
0.45	GO:0019904	protein domain specific binding
0.40	GO:0003743	translation initiation factor activity
0.34	GO:0005549	odorant binding
0.34	GO:0003713	transcription coactivator activity
0.34	GO:0008083	growth factor activity
0.33	GO:0004252	serine-type endopeptidase activity

0.61	GO:0005634	nucleus
0.49	GO:0000428	DNA-directed RNA polymerase complex
0.49	GO:0005667	transcription factor complex
0.46	GO:0031974	membrane-enclosed lumen
0.45	GO:0030054	cell junction
0.42	GO:0044446	intracellular organelle part
0.33	GO:0005576	extracellular region
0.31	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0004252

tr|T1FM78|T1FM78_HELRO
NAD-dependent protein deacylase
Search

SIRT5

0.55	NAD-dependent protein deacylase

0.79	GO:0036048	protein desuccinylation
0.79	GO:0036046	protein demalonylation
0.74	GO:0006476	protein deacetylation
0.70	GO:0018205	peptidyl-lysine modification
0.55	GO:0061699	peptidyl-lysine deglutarylation
0.51	GO:2000378	negative regulation of reactive oxygen species metabolic process
0.51	GO:0010566	regulation of ketone biosynthetic process
0.39	GO:0010667	negative regulation of cardiac muscle cell apoptotic process
0.39	GO:0072383	plus-end-directed vesicle transport along microtubule
0.37	GO:0031667	response to nutrient levels

0.79	GO:0036055	protein-succinyllysine desuccinylase activity
0.79	GO:0036054	protein-malonyllysine demalonylase activity
0.74	GO:0070403	NAD+ binding
0.73	GO:0034979	NAD-dependent protein deacetylase activity
0.60	GO:0008270	zinc ion binding
0.55	GO:0061697	protein-glutaryllysine deglutarylase activity
0.37	GO:0003777	microtubule motor activity
0.36	GO:0008017	microtubule binding
0.34	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.34	GO:0030554	adenyl nucleotide binding

0.60	GO:0005829	cytosol
0.58	GO:0005739	mitochondrion
0.55	GO:0005634	nucleus
0.48	GO:0031970	organelle envelope lumen
0.42	GO:0019866	organelle inner membrane

0.34

EC:2.4.2.30

GO:0003950

tr|T1FM79|T1FM79_HELRO
Uncharacterized protein
Search

0.48	Prohibitin protein WPH

0.43	GO:0071456	cellular response to hypoxia
0.40	GO:0030421	defecation
0.40	GO:0043051	regulation of pharyngeal pumping
0.40	GO:0040008	regulation of growth
0.40	GO:0002082	regulation of oxidative phosphorylation
0.39	GO:0070584	mitochondrion morphogenesis
0.38	GO:0008406	gonad development
0.38	GO:0048477	oogenesis
0.38	GO:0045917	positive regulation of complement activation
0.38	GO:0007283	spermatogenesis

0.39	GO:0001850	complement component C3a binding
0.38	GO:0001851	complement component C3b binding
0.38	GO:0031871	proteinase activated receptor binding
0.37	GO:0042826	histone deacetylase binding
0.37	GO:0008022	protein C-terminus binding
0.36	GO:0044212	transcription regulatory region DNA binding
0.36	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding

0.41	GO:0035632	mitochondrial prohibitin complex
0.37	GO:0043209	myelin sheath
0.37	GO:0005769	early endosome
0.36	GO:0009986	cell surface
0.35	GO:0005654	nucleoplasm
0.35	GO:0005887	integral component of plasma membrane

tr|T1FM80|T1FM80_HELRO
Uncharacterized protein
Search

U2AF1

0.85	U2 small nuclear RNA auxiliary factor small subunit

0.75

GO:0000398

mRNA splicing, via spliceosome

0.59	GO:0003723	RNA binding
0.54	GO:0046872	metal ion binding
0.46	GO:0050733	RS domain binding

0.84	GO:0089701	U2AF
0.48	GO:0005681	spliceosomal complex
0.43	GO:0016607	nuclear speck
0.30	GO:0016021	integral component of membrane

tr|T1FM81|T1FM81_HELRO
Uncharacterized protein
Search

tr|T1FM82|T1FM82_HELRO
Calponin
Search

0.71	Muscle-specific protein 20

0.77	GO:0031032	actomyosin structure organization
0.43	GO:0000902	cell morphogenesis
0.34	GO:0030855	epithelial cell differentiation
0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression
0.34	GO:0006886	intracellular protein transport
0.33	GO:0016192	vesicle-mediated transport

0.72	GO:0003779	actin binding
0.71	GO:0005516	calmodulin binding
0.46	GO:0032403	protein complex binding
0.35	GO:0043565	sequence-specific DNA binding

0.43	GO:0005856	cytoskeleton
0.34	GO:0030131	clathrin adaptor complex
0.34	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

tr|T1FM83|T1FM83_HELRO
Uncharacterized protein
Search

TMBIM6

0.88	Transmembrane BAX inhibitor motif containing 6

0.66	GO:0043066	negative regulation of apoptotic process
0.54	GO:0031438	negative regulation of mRNA cleavage
0.54	GO:1904720	regulation of mRNA endonucleolytic cleavage involved in unfolded protein response
0.53	GO:1903895	negative regulation of IRE1-mediated unfolded protein response
0.53	GO:0051025	negative regulation of immunoglobulin secretion
0.53	GO:1902065	response to L-glutamate
0.53	GO:1903297	regulation of hypoxia-induced intrinsic apoptotic signaling pathway
0.52	GO:1990441	negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
0.52	GO:1900038	negative regulation of cellular response to hypoxia
0.51	GO:0033119	negative regulation of RNA splicing

0.50	GO:0060698	endoribonuclease inhibitor activity
0.48	GO:0031625	ubiquitin protein ligase binding

0.46	GO:0005789	endoplasmic reticulum membrane
0.42	GO:0031966	mitochondrial membrane
0.33	GO:0005887	integral component of plasma membrane
0.33	GO:0005634	nucleus

tr|T1FM84|T1FM84_HELRO
Uncharacterized protein
Search

COPS2

0.78	COP9 constitutive photomorphogenic homolog subunit 2

0.83	GO:0035914	skeletal muscle cell differentiation
0.83	GO:0000338	protein deneddylation
0.76	GO:0008283	cell proliferation
0.71	GO:0045892	negative regulation of transcription, DNA-templated
0.56	GO:0022008	neurogenesis
0.42	GO:0006357	regulation of transcription by RNA polymerase II
0.39	GO:0043687	post-translational protein modification
0.39	GO:0000715	nucleotide-excision repair, DNA damage recognition
0.39	GO:0006283	transcription-coupled nucleotide-excision repair
0.38	GO:0006366	transcription by RNA polymerase II

0.80	GO:0003714	transcription corepressor activity
0.40	GO:0005515	protein binding
0.36	GO:0004871	signal transducer activity

0.80	GO:0008180	COP9 signalosome
0.48	GO:0005737	cytoplasm
0.37	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

tr|T1FM85|T1FM85_HELRO
Uncharacterized protein
Search

DHPS

0.56	Deoxyhypusine synthase

0.82	GO:0008612	peptidyl-lysine modification to peptidyl-hypusine
0.48	GO:0042102	positive regulation of T cell proliferation
0.46	GO:0042593	glucose homeostasis
0.45	GO:0008216	spermidine metabolic process
0.38	GO:0006888	ER to Golgi vesicle-mediated transport
0.38	GO:0006598	polyamine catabolic process
0.38	GO:0051289	protein homotetramerization
0.38	GO:0031017	exocrine pancreas development
0.38	GO:0003323	type B pancreatic cell development
0.37	GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly

0.56	GO:0034038	deoxyhypusine synthase activity
0.44	GO:0042802	identical protein binding
0.35	GO:0050514	homospermidine synthase (spermidine-specific) activity
0.33	GO:0050660	flavin adenine dinucleotide binding

0.36	GO:0005737	cytoplasm
0.32	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.56

EC:2.5.1.46

GO:0034038

tr|T1FM86|T1FM86_HELRO
Uncharacterized protein
Search

0.83	Tumor differentially expressed protein 1

0.79	GO:0006658	phosphatidylserine metabolic process
0.74	GO:0006665	sphingolipid metabolic process
0.50	GO:0015825	L-serine transport
0.50	GO:0009597	detection of virus
0.49	GO:1902237	positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
0.45	GO:0045087	innate immune response
0.45	GO:0051607	defense response to virus
0.39	GO:1904219	positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity
0.39	GO:1904222	positive regulation of serine C-palmitoyltransferase activity
0.36	GO:0044091	membrane biogenesis

0.50	GO:0015194	L-serine transmembrane transporter activity
0.37	GO:0030674	protein binding, bridging
0.36	GO:0019899	enzyme binding

0.60	GO:0005789	endoplasmic reticulum membrane
0.43	GO:0005794	Golgi apparatus
0.42	GO:0005886	plasma membrane
0.35	GO:0098588	bounding membrane of organelle
0.35	GO:0070062	extracellular exosome
0.34	GO:0048471	perinuclear region of cytoplasm
0.33	GO:1990234	transferase complex
0.30	GO:0016021	integral component of membrane

tr|T1FM87|T1FM87_HELRO
Uncharacterized protein
Search

0.11	Putative sodium/potassium-transporting ATPase subunit beta-2

0.73	GO:0006814	sodium ion transport
0.71	GO:0006813	potassium ion transport
0.40	GO:0048923	posterior lateral line neuromast hair cell differentiation
0.40	GO:0048840	otolith development
0.40	GO:0001964	startle response
0.39	GO:0042472	inner ear morphogenesis
0.38	GO:0007507	heart development
0.35	GO:0007017	microtubule-based process

0.35	GO:0003924	GTPase activity
0.35	GO:0008080	N-acetyltransferase activity
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0019001	guanyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.85	GO:0005890	sodium:potassium-exchanging ATPase complex
0.35	GO:0005874	microtubule

0.35

GO:0008080

tr|T1FM88|T1FM88_HELRO
Protein transport protein Sec61 subunit beta
Search

0.75	Transport protein Sec61 subunit beta

0.69	GO:0006886	intracellular protein transport
0.50	GO:1903513	endoplasmic reticulum to cytosol transport
0.48	GO:0030433	ubiquitin-dependent ERAD pathway
0.48	GO:0006606	protein import into nucleus
0.44	GO:0072599	establishment of protein localization to endoplasmic reticulum
0.43	GO:0090150	establishment of protein localization to membrane
0.43	GO:0071806	protein transmembrane transport
0.41	GO:0065009	regulation of molecular function
0.41	GO:0010507	negative regulation of autophagy
0.35	GO:0036498	IRE1-mediated unfolded protein response

0.53	GO:0048408	epidermal growth factor binding
0.46	GO:0005086	ARF guanyl-nucleotide exchange factor activity
0.44	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
0.34	GO:0043022	ribosome binding
0.33	GO:0003723	RNA binding

0.84	GO:0005784	Sec61 translocon complex
0.48	GO:0031205	endoplasmic reticulum Sec complex
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|T1FM89|T1FM89_HELRO
Uncharacterized protein
Search

0.78	Myosin tail

0.54	GO:0007018	microtubule-based movement
0.38	GO:0060279	positive regulation of ovulation
0.38	GO:0030241	skeletal muscle myosin thick filament assembly
0.38	GO:0060298	positive regulation of sarcomere organization
0.35	GO:0040011	locomotion
0.33	GO:0009903	chloroplast avoidance movement
0.33	GO:0009904	chloroplast accumulation movement
0.33	GO:0006233	dTDP biosynthetic process
0.33	GO:0006235	dTTP biosynthetic process
0.32	GO:0000724	double-strand break repair via homologous recombination

0.72	GO:0003774	motor activity
0.55	GO:0051015	actin filament binding
0.54	GO:0008017	microtubule binding
0.44	GO:0030554	adenyl nucleotide binding
0.43	GO:0097367	carbohydrate derivative binding
0.43	GO:0008144	drug binding
0.43	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0017124	SH3 domain binding
0.36	GO:0019901	protein kinase binding
0.33	GO:0004798	thymidylate kinase activity

0.76	GO:0016459	myosin complex
0.44	GO:0030016	myofibril
0.36	GO:0044449	contractile fiber part
0.34	GO:0005576	extracellular region
0.33	GO:0030915	Smc5-Smc6 complex
0.32	GO:0099070	static microtubule bundle
0.32	GO:0005815	microtubule organizing center
0.32	GO:0005829	cytosol
0.32	GO:0005883	neurofilament
0.32	GO:0032155	cell division site part

0.33

EC:2.7.4.9

GO:0004798

tr|T1FM90|T1FM90_HELRO
Uncharacterized protein
Search

OTUB1

0.88	Ubiquitin thioesterase

0.74	GO:0071108	protein K48-linked deubiquitination
0.51	GO:1901314	regulation of histone H2A K63-linked ubiquitination
0.51	GO:0033183	negative regulation of histone ubiquitination
0.51	GO:1900045	negative regulation of protein K63-linked ubiquitination
0.49	GO:2000780	negative regulation of double-strand break repair
0.42	GO:0006974	cellular response to DNA damage stimulus
0.38	GO:0071347	cellular response to interleukin-1
0.37	GO:0002250	adaptive immune response
0.34	GO:0006259	DNA metabolic process

0.76	GO:0019784	NEDD8-specific protease activity
0.75	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.71	GO:0043130	ubiquitin binding
0.46	GO:0031625	ubiquitin protein ligase binding
0.33	GO:0008080	N-acetyltransferase activity

0.55	GO:0005634	nucleus
0.36	GO:0070062	extracellular exosome
0.33	GO:0005829	cytosol
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part

0.33

GO:0008080

tr|T1FM91|T1FM91_HELRO
Dihydrolipoyl dehydrogenase
Search

DLD

0.46	Dihydrolipoyl dehydrogenase

0.69	GO:0045454	cell redox homeostasis
0.60	GO:0022900	electron transport chain
0.49	GO:0018335	protein succinylation
0.47	GO:0048240	sperm capacitation
0.45	GO:0007369	gastrulation
0.45	GO:0006086	acetyl-CoA biosynthetic process from pyruvate
0.44	GO:0042391	regulation of membrane potential
0.42	GO:0060047	heart contraction
0.40	GO:0006119	oxidative phosphorylation
0.40	GO:0045333	cellular respiration

0.78	GO:0004148	dihydrolipoyl dehydrogenase activity
0.66	GO:0050660	flavin adenine dinucleotide binding
0.62	GO:0009055	electron transfer activity
0.48	GO:0034604	pyruvate dehydrogenase (NAD+) activity
0.35	GO:0043544	lipoamide binding
0.33	GO:0051287	NAD binding

0.48	GO:0043159	acrosomal matrix
0.46	GO:0045240	dihydrolipoyl dehydrogenase complex
0.45	GO:0043209	myelin sheath
0.44	GO:0045254	pyruvate dehydrogenase complex
0.44	GO:0005929	cilium
0.42	GO:0031974	membrane-enclosed lumen
0.42	GO:1990234	transferase complex
0.41	GO:0044428	nuclear part
0.40	GO:0005739	mitochondrion
0.34	GO:0005960	glycine cleavage complex

0.78	EC:1.8.1.4	GO:0004148
0.48	KEGG:R00209	GO:0034604

tr|T1FM92|T1FM92_HELRO
Uncharacterized protein
Search

PHYH

0.84	LOW QUALITY PROTEIN: phytanoyl-CoA dioxygenase, peroxisomal

0.63	GO:0001561	fatty acid alpha-oxidation
0.53	GO:0097089	methyl-branched fatty acid metabolic process
0.48	GO:0006103	2-oxoglutarate metabolic process
0.45	GO:0006720	isoprenoid metabolic process
0.33	GO:0055085	transmembrane transport

0.66	GO:0051213	dioxygenase activity
0.51	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.47	GO:0008198	ferrous iron binding
0.45	GO:0043177	organic acid binding
0.39	GO:0048037	cofactor binding
0.38	GO:0043168	anion binding
0.37	GO:0048029	monosaccharide binding
0.36	GO:0019842	vitamin binding
0.33	GO:0005515	protein binding
0.33	GO:0005215	transporter activity

0.47	GO:0005777	peroxisome
0.41	GO:0005739	mitochondrion
0.35	GO:0031907	microbody lumen
0.30	GO:0016020	membrane

0.51

GO:0016705

tr|T1FM93|T1FM93_HELRO
Uncharacterized protein
Search

0.11	UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase

0.37	GO:0006811	ion transport
0.35	GO:0045454	cell redox homeostasis
0.34	GO:0055114	oxidation-reduction process
0.33	GO:0009058	biosynthetic process
0.33	GO:0006629	lipid metabolic process

0.47	GO:0008483	transaminase activity
0.35	GO:0030170	pyridoxal phosphate binding
0.34	GO:0008609	alkylglycerone-phosphate synthase activity
0.34	GO:0000062	fatty-acyl-CoA binding
0.34	GO:0016746	transferase activity, transferring acyl groups
0.34	GO:0016491	oxidoreductase activity
0.33	GO:0050660	flavin adenine dinucleotide binding
0.32	GO:0003676	nucleic acid binding

0.43	GO:0005921	gap junction
0.37	GO:0005886	plasma membrane
0.34	GO:0019028	viral capsid
0.30	GO:0044425	membrane part

0.47

GO:0008483

tr|T1FM94|T1FM94_HELRO
Peptidylprolyl isomerase
Search

FKBP4

0.44	Peptidylprolyl isomerase

0.72	GO:0000413	protein peptidyl-prolyl isomerization
0.51	GO:0006463	steroid hormone receptor complex assembly
0.49	GO:0030521	androgen receptor signaling pathway
0.49	GO:0030850	prostate gland development
0.49	GO:0061077	chaperone-mediated protein folding
0.48	GO:0007566	embryo implantation
0.47	GO:0046661	male sex differentiation
0.47	GO:0031503	protein complex localization
0.39	GO:0031111	negative regulation of microtubule polymerization or depolymerization
0.39	GO:0010977	negative regulation of neuron projection development

0.82	GO:0005528	FK506 binding
0.74	GO:0031072	heat shock protein binding
0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.50	GO:0035259	glucocorticoid receptor binding
0.48	GO:0051219	phosphoprotein binding
0.42	GO:0032550	purine ribonucleoside binding
0.42	GO:0019001	guanyl nucleotide binding
0.39	GO:0048156	tau protein binding
0.38	GO:0032767	copper-dependent protein binding
0.38	GO:0032559	adenyl ribonucleotide binding

0.43	GO:0005654	nucleoplasm
0.43	GO:0005829	cytosol
0.40	GO:0044295	axonal growth cone
0.37	GO:0005874	microtubule
0.37	GO:0043025	neuronal cell body
0.36	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0070062	extracellular exosome
0.35	GO:0005739	mitochondrion
0.34	GO:0043234	protein complex

0.72

GO:0003755

tr|T1FM95|T1FM95_HELRO
Cyclin-dependent kinases regulatory subunit
Search

CKS1B

0.67	Cyclin-dependent kinases regulatory subunit

0.76	GO:0045859	regulation of protein kinase activity
0.67	GO:0051301	cell division
0.67	GO:0007049	cell cycle
0.50	GO:0008283	cell proliferation
0.49	GO:0016310	phosphorylation
0.49	GO:0045787	positive regulation of cell cycle
0.49	GO:0033674	positive regulation of kinase activity
0.48	GO:0001934	positive regulation of protein phosphorylation
0.48	GO:0007346	regulation of mitotic cell cycle
0.47	GO:0045893	positive regulation of transcription, DNA-templated

0.82	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity
0.51	GO:0043539	protein serine/threonine kinase activator activity
0.51	GO:0016301	kinase activity
0.50	GO:0043130	ubiquitin binding
0.49	GO:0042393	histone binding
0.49	GO:0019901	protein kinase binding
0.43	GO:0003682	chromatin binding
0.32	GO:0003676	nucleic acid binding

0.51	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.51	GO:0019005	SCF ubiquitin ligase complex
0.33	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

0.82

GO:0016538

tr|T1FM96|T1FM96_HELRO
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
Search

DBT

0.44	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex

0.40

GO:0009081

branched-chain amino acid metabolic process

0.63	GO:0016746	transferase activity, transferring acyl groups
0.42	GO:0031625	ubiquitin protein ligase binding

0.43

GO:0042645

mitochondrial nucleoid

0.63

EC:2.3

GO:0016746

tr|T1FM97|T1FM97_HELRO
Queuine tRNA-ribosyltransferase accessory subunit 2
Search

0.39	Queuine tRNA-ribosyltransferase accessory subunit 2

0.76	GO:0101030	tRNA-guanine transglycosylation
0.55	GO:0008616	queuosine biosynthetic process

0.79	GO:0008479	queuine tRNA-ribosyltransferase activity
0.53	GO:0046872	metal ion binding

0.46

GO:0005737

cytoplasm

0.79

EC:2.4.2.29

GO:0008479

tr|T1FM98|T1FM98_HELRO
Uncharacterized protein
Search

0.48	GO:0043484	regulation of RNA splicing
0.37	GO:0007311	maternal specification of dorsal/ventral axis, oocyte, germ-line encoded
0.37	GO:0060445	branching involved in salivary gland morphogenesis
0.37	GO:0060441	epithelial tube branching involved in lung morphogenesis
0.36	GO:0000380	alternative mRNA splicing, via spliceosome
0.36	GO:0045451	pole plasm oskar mRNA localization
0.36	GO:0050679	positive regulation of epithelial cell proliferation
0.36	GO:0046427	positive regulation of JAK-STAT cascade
0.35	GO:0042060	wound healing
0.34	GO:0006417	regulation of translation

0.59	GO:0003723	RNA binding
0.34	GO:0005515	protein binding
0.33	GO:0005328	neurotransmitter:sodium symporter activity
0.33	GO:0004672	protein kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0003677	DNA binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.50	GO:0019013	viral nucleocapsid
0.46	GO:0016604	nuclear body
0.45	GO:0030529	intracellular ribonucleoprotein complex
0.34	GO:0000786	nucleosome
0.33	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

tr|T1FM99|T1FM99_HELRO
Aconitate hydratase, mitochondrial
Search

0.69	Aconitate hydratase, mitochondrial

0.70	GO:0006099	tricarboxylic acid cycle
0.39	GO:0035900	response to isolation stress
0.37	GO:0001889	liver development
0.37	GO:0006102	isocitrate metabolic process

0.79	GO:0003994	aconitate hydratase activity
0.67	GO:0051539	4 iron, 4 sulfur cluster binding
0.52	GO:0046872	metal ion binding
0.36	GO:0051538	3 iron, 4 sulfur cluster binding
0.33	GO:0005515	protein binding

0.59	GO:0005739	mitochondrion
0.41	GO:0043209	myelin sheath
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.79

EC:4.2.1.3

GO:0003994

tr|T1FMA0|T1FMA0_HELRO
DNA helicase
Search

MCM6

0.44	Zygotic DNA replication licensing factor mcm6-B

0.75	GO:0006270	DNA replication initiation
0.65	GO:0032392	DNA geometric change
0.58	GO:0007049	cell cycle
0.57	GO:0030174	regulation of DNA-dependent DNA replication initiation

0.66	GO:0003678	DNA helicase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.55	GO:0003677	DNA binding
0.54	GO:0003682	chromatin binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0042802	identical protein binding
0.47	GO:0070035	purine NTP-dependent helicase activity
0.47	GO:0016887	ATPase activity
0.44	GO:0046872	metal ion binding

0.73	GO:0042555	MCM complex
0.58	GO:0005634	nucleus
0.49	GO:0044427	chromosomal part
0.46	GO:0031974	membrane-enclosed lumen

0.47

EC:3.6.1.3

GO:0016887

tr|T1FMA1|T1FMA1_HELRO
Uncharacterized protein
Search

0.88	Endonuclease, polyU-specific C

0.70	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.34	GO:0043144	snoRNA processing
0.34	GO:0006955	immune response
0.34	GO:0006898	receptor-mediated endocytosis
0.34	GO:0007565	female pregnancy
0.33	GO:0007034	vacuolar transport
0.33	GO:0006508	proteolysis
0.33	GO:0030001	metal ion transport

0.71	GO:0004521	endoribonuclease activity
0.35	GO:0003723	RNA binding
0.35	GO:0005044	scavenger receptor activity
0.34	GO:0001871	pattern binding
0.34	GO:0046872	metal ion binding
0.34	GO:0030246	carbohydrate binding
0.33	GO:0008233	peptidase activity
0.33	GO:0017171	serine hydrolase activity

0.34	GO:0005634	nucleus
0.33	GO:0005576	extracellular region
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.33

GO:0008233

tr|T1FMA2|T1FMA2_HELRO
Uncharacterized protein
Search

0.85	Endonuclease, polyU-specific C

0.70	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.38	GO:0006955	immune response
0.37	GO:0006898	receptor-mediated endocytosis
0.34	GO:0043144	snoRNA processing
0.33	GO:0006508	proteolysis

0.71	GO:0004521	endoribonuclease activity
0.39	GO:0005044	scavenger receptor activity
0.38	GO:0030247	polysaccharide binding
0.34	GO:0003723	RNA binding
0.33	GO:0008233	peptidase activity
0.33	GO:0046872	metal ion binding

0.34	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0008233

tr|T1FMA3|T1FMA3_HELRO
Uncharacterized protein
Search

ZCCHC4

0.73	Zinc finger CCHC domain-containing protein 4

0.53

GO:0032259

methylation

0.63	GO:0008270	zinc ion binding
0.54	GO:0008168	methyltransferase activity
0.49	GO:0003676	nucleic acid binding
0.37	GO:0016746	transferase activity, transferring acyl groups

0.30

GO:0031224

intrinsic component of membrane

0.54

GO:0008168

tr|T1FMA4|T1FMA4_HELRO
Tetraspanin
Search

0.36	Tetraspanin

0.37

GO:0007166

cell surface receptor signaling pathway

0.36

GO:0005887

integral component of plasma membrane

tr|T1FMA5|T1FMA5_HELRO
Transcription factor BTF3
Search

0.78	Transcription factor BTF3

0.63	GO:0009792	embryo development ending in birth or egg hatching
0.46	GO:0043066	negative regulation of apoptotic process
0.42	GO:0015031	protein transport
0.40	GO:0006351	transcription, DNA-templated
0.39	GO:1903506	regulation of nucleic acid-templated transcription
0.39	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.39	GO:0010468	regulation of gene expression

0.64	GO:0005829	cytosol
0.42	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016020	membrane

tr|T1FMA6|T1FMA6_HELRO
Uncharacterized protein
Search

0.71	Putative carboxypeptidase 7

0.61	GO:0006508	proteolysis
0.37	GO:0007186	G-protein coupled receptor signaling pathway

0.72	GO:0004180	carboxypeptidase activity
0.54	GO:0008237	metallopeptidase activity
0.41	GO:0046872	metal ion binding
0.37	GO:0004930	G-protein coupled receptor activity

0.30

GO:0031224

intrinsic component of membrane

tr|T1FMA7|T1FMA7_HELRO
Uncharacterized protein
Search

RMND5A

0.95	Required for meiotic nuclear division 5 homolog A

0.65	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.62	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process

0.59	GO:0004842	ubiquitin-protein transferase activity
0.49	GO:0046872	metal ion binding

0.70	GO:0034657	GID complex
0.51	GO:0005634	nucleus
0.43	GO:0005737	cytoplasm

0.59

GO:0004842

tr|T1FMA8|T1FMA8_HELRO
Uncharacterized protein
Search

PLRG1

0.50	Pleiotropic regulator 1

0.72	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle
0.67	GO:0034504	protein localization to nucleus
0.58	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator
0.58	GO:0000398	mRNA splicing, via spliceosome
0.53	GO:0043066	negative regulation of apoptotic process
0.37	GO:0030168	platelet activation
0.36	GO:0051258	protein polymerization
0.34	GO:0007165	signal transduction

0.41	GO:0004386	helicase activity
0.38	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0003676	nucleic acid binding
0.37	GO:0030674	protein binding, bridging
0.36	GO:0005102	receptor binding

0.79	GO:0005662	DNA replication factor A complex
0.74	GO:0071013	catalytic step 2 spliceosome
0.69	GO:0001650	fibrillar center
0.68	GO:0005684	U2-type spliceosomal complex
0.67	GO:0016607	nuclear speck
0.67	GO:0031965	nuclear membrane
0.64	GO:0071011	precatalytic spliceosome
0.64	GO:0000974	Prp19 complex
0.63	GO:0080008	Cul4-RING E3 ubiquitin ligase complex
0.38	GO:0005577	fibrinogen complex

tr|T1FMA9|T1FMA9_HELRO
Uncharacterized protein
Search

0.41	Eukaryotic translation elongation factor

0.61	GO:0006414	translational elongation
0.36	GO:0045727	positive regulation of translation
0.36	GO:0002244	hematopoietic progenitor cell differentiation

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.62	GO:0003746	translation elongation factor activity
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0045296	cadherin binding
0.36	GO:0019901	protein kinase binding

0.37	GO:0016235	aggresome
0.36	GO:0005829	cytosol
0.36	GO:0005844	polysome
0.35	GO:0019013	viral nucleocapsid
0.34	GO:0005886	plasma membrane

tr|T1FMB0|T1FMB0_HELRO
Uncharacterized protein
Search

0.19	Kelch domain-containing protein 1

0.59

GO:0003723

RNA binding

tr|T1FMB1|T1FMB1_HELRO
Uncharacterized protein
Search

GPSM2

0.93	G-protein-signaling modulator 2

0.66	GO:0050790	regulation of catalytic activity
0.59	GO:1905832	positive regulation of spindle assembly
0.58	GO:1904778	positive regulation of protein localization to cell cortex
0.58	GO:0051661	maintenance of centrosome location
0.58	GO:0031291	Ran protein signal transduction
0.56	GO:0000132	establishment of mitotic spindle orientation
0.55	GO:0060236	regulation of mitotic spindle organization
0.54	GO:0007052	mitotic spindle organization
0.38	GO:1905098	negative regulation of guanyl-nucleotide exchange factor activity
0.37	GO:0016239	positive regulation of macroautophagy

0.73	GO:0030695	GTPase regulator activity
0.57	GO:0001965	G-protein alpha-subunit binding
0.56	GO:0043621	protein self-association
0.55	GO:0070840	dynein complex binding
0.54	GO:0008022	protein C-terminus binding
0.51	GO:0019904	protein domain specific binding
0.50	GO:0042802	identical protein binding
0.33	GO:1901265	nucleoside phosphate binding
0.33	GO:0036094	small molecule binding

0.58	GO:0097575	lateral cell cortex
0.56	GO:0097431	mitotic spindle pole
0.52	GO:0005813	centrosome
0.49	GO:0005829	cytosol
0.44	GO:0043234	protein complex
0.42	GO:0005794	Golgi apparatus
0.40	GO:0005654	nucleoplasm
0.36	GO:0016328	lateral plasma membrane
0.36	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0098588	bounding membrane of organelle

tr|T1FMB2|T1FMB2_HELRO
Uncharacterized protein
Search

TAT

0.83	Tyrosine aminotransferase

0.68	GO:0009072	aromatic amino acid family metabolic process
0.56	GO:0009063	cellular amino acid catabolic process
0.54	GO:1901361	organic cyclic compound catabolic process
0.54	GO:0019439	aromatic compound catabolic process
0.49	GO:0009058	biosynthetic process
0.43	GO:0006103	2-oxoglutarate metabolic process
0.41	GO:0006536	glutamate metabolic process
0.34	GO:1902221	erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process
0.33	GO:0042737	drug catabolic process

0.86	GO:0070547	L-tyrosine aminotransferase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.39	GO:0070546	L-phenylalanine aminotransferase activity
0.34	GO:0005201	extracellular matrix structural constituent
0.34	GO:0016597	amino acid binding

0.38	GO:0005739	mitochondrion
0.34	GO:0005604	basement membrane
0.34	GO:0005581	collagen trimer
0.30	GO:0016020	membrane

tr|T1FMB3|T1FMB3_HELRO
Innexin
Search

INX

0.64	Innexin unc-9

0.59	GO:0006811	ion transport
0.42	GO:0006367	transcription initiation from RNA polymerase II promoter
0.36	GO:0010644	cell communication by electrical coupling
0.33	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:0055085	transmembrane transport

0.36	GO:0005243	gap junction channel activity
0.33	GO:0004930	G-protein coupled receptor activity

0.81	GO:0005921	gap junction
0.55	GO:0005886	plasma membrane
0.42	GO:0005669	transcription factor TFIID complex
0.35	GO:0045202	synapse
0.30	GO:0016021	integral component of membrane

tr|T1FMB4|T1FMB4_HELRO
Uncharacterized protein
Search

0.49	Sister chromatid cohesion protein DCC1

0.82

GO:0007064

mitotic sister chromatid cohesion

0.84

GO:0031390

Ctf18 RFC-like complex

tr|T1FMB5|T1FMB5_HELRO
Proliferating cell nuclear antigen
Search

PCNA

0.66	Proliferating cell nuclear antigen

0.77	GO:0006275	regulation of DNA replication
0.66	GO:0006260	DNA replication
0.56	GO:0019985	translesion synthesis
0.55	GO:0032077	positive regulation of deoxyribonuclease activity
0.53	GO:0045739	positive regulation of DNA repair
0.53	GO:0034644	cellular response to UV
0.51	GO:0006298	mismatch repair
0.50	GO:0030855	epithelial cell differentiation
0.48	GO:0010557	positive regulation of macromolecule biosynthetic process
0.48	GO:0031328	positive regulation of cellular biosynthetic process

0.84	GO:0030337	DNA polymerase processivity factor activity
0.57	GO:0000701	purine-specific mismatch base pair DNA N-glycosylase activity
0.56	GO:0032405	MutLalpha complex binding
0.55	GO:0032139	dinucleotide insertion or deletion binding
0.55	GO:0070182	DNA polymerase binding
0.55	GO:0035035	histone acetyltransferase binding
0.53	GO:0030971	receptor tyrosine kinase binding
0.50	GO:0003682	chromatin binding
0.48	GO:0042802	identical protein binding
0.48	GO:0003684	damaged DNA binding

0.61	GO:0005634	nucleus
0.58	GO:0043626	PCNA complex
0.50	GO:0005813	centrosome
0.49	GO:0005657	replication fork
0.46	GO:0070013	intracellular organelle lumen
0.37	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.35	GO:0070062	extracellular exosome
0.35	GO:0000781	chromosome, telomeric region
0.33	GO:0032993	protein-DNA complex
0.30	GO:0016020	membrane

0.57

EC:3.2.2

GO:0000701

tr|T1FMB6|T1FMB6_HELRO
Uncharacterized protein
Search

0.58	USP-like protein isoform 1

0.62

GO:0006950

response to stress

tr|T1FMB7|T1FMB7_HELRO
Uncharacterized protein
Search

TID

0.85	DnaJ subfamily A member 3, mitochondrial

0.74	GO:0009408	response to heat
0.69	GO:0006457	protein folding
0.42	GO:0006924	activation-induced cell death of T cells
0.42	GO:0006264	mitochondrial DNA replication
0.41	GO:0033077	T cell differentiation in thymus
0.41	GO:0042102	positive regulation of T cell proliferation
0.41	GO:0007528	neuromuscular junction development
0.40	GO:0007569	cell aging
0.40	GO:0008285	negative regulation of cell proliferation
0.40	GO:0000122	negative regulation of transcription by RNA polymerase II

0.78	GO:0031072	heat shock protein binding
0.71	GO:0051082	unfolded protein binding
0.54	GO:0030554	adenyl nucleotide binding
0.54	GO:0046872	metal ion binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0032555	purine ribonucleotide binding
0.39	GO:0030695	GTPase regulator activity
0.39	GO:0005133	interferon-gamma receptor binding
0.38	GO:0051059	NF-kappaB binding

0.41	GO:0042645	mitochondrial nucleoid
0.41	GO:0005884	actin filament
0.41	GO:0031594	neuromuscular junction
0.40	GO:0045211	postsynaptic membrane
0.39	GO:0019897	extrinsic component of plasma membrane
0.39	GO:0033256	I-kappaB/NF-kappaB complex
0.39	GO:0008385	IkappaB kinase complex
0.36	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

tr|T1FMB8|T1FMB8_HELRO
Uncharacterized protein
Search

0.65	Protein that may be involved in binding ubiquitin-conjugating enzyme (Fragment)

0.66	GO:0006336	DNA replication-independent nucleosome assembly
0.60	GO:0006511	ubiquitin-dependent protein catabolic process
0.40	GO:0017004	cytochrome complex assembly
0.39	GO:0006886	intracellular protein transport
0.36	GO:0055114	oxidation-reduction process

0.69	GO:0031624	ubiquitin conjugating enzyme binding
0.66	GO:0043130	ubiquitin binding
0.36	GO:0046872	metal ion binding

0.44	GO:0005737	cytoplasm
0.40	GO:0097708	intracellular vesicle
0.40	GO:0098805	whole membrane
0.40	GO:0098588	bounding membrane of organelle
0.39	GO:0012505	endomembrane system
0.37	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

tr|T1FMB9|T1FMB9_HELRO
DNA polymerase alpha subunit B
Search

0.41	DNA polymerase alpha subunit B

0.67	GO:0071897	DNA biosynthetic process
0.66	GO:0006260	DNA replication
0.45	GO:0000060	protein import into nucleus, translocation

0.71	GO:0003887	DNA-directed DNA polymerase activity
0.55	GO:0003677	DNA binding
0.44	GO:0046982	protein heterodimerization activity

0.57	GO:0005634	nucleus
0.45	GO:0000428	DNA-directed RNA polymerase complex
0.44	GO:0030894	replisome
0.43	GO:0031974	membrane-enclosed lumen
0.41	GO:0005829	cytosol
0.37	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.71

GO:0003887

tr|T1FMC0|T1FMC0_HELRO
Uncharacterized protein
Search

ALKBH3

0.42	Alpha-ketoglutarate-dependent dioxygenase alkB

0.66	GO:0035552	oxidative single-stranded DNA demethylation
0.62	GO:0006307	DNA dealkylation involved in DNA repair
0.37	GO:0032259	methylation

0.62	GO:0051213	dioxygenase activity
0.37	GO:0008168	methyltransferase activity

0.37

GO:0008168

tr|T1FMC1|T1FMC1_HELRO
T-complex protein 1 subunit gamma
Search

CCT3

0.69	T-complex protein 1 subunit gamma

0.69	GO:0006457	protein folding
0.52	GO:1904869	regulation of protein localization to Cajal body
0.51	GO:1904874	positive regulation of telomerase RNA localization to Cajal body
0.50	GO:0032212	positive regulation of telomere maintenance via telomerase
0.49	GO:1900182	positive regulation of protein localization to nucleus
0.49	GO:0046931	pore complex assembly
0.49	GO:0007339	binding of sperm to zona pellucida
0.48	GO:0050821	protein stabilization
0.47	GO:1901998	toxin transport
0.44	GO:0046671	negative regulation of retinal cell programmed cell death

0.71	GO:0051082	unfolded protein binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0044183	protein binding involved in protein folding
0.34	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.33	GO:0003723	RNA binding
0.33	GO:0046983	protein dimerization activity

0.52	GO:0005832	chaperonin-containing T-complex
0.50	GO:0002199	zona pellucida receptor complex
0.47	GO:0043209	myelin sheath
0.47	GO:0044297	cell body
0.45	GO:0005874	microtubule
0.39	GO:0005886	plasma membrane
0.36	GO:0070062	extracellular exosome
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

tr|T1FMC2|T1FMC2_HELRO
Uncharacterized protein
Search

tr|T1FMC3|T1FMC3_HELRO
Uncharacterized protein
Search

NPLOC4

0.93	NPL4 homolog, ubiquitin recognition factor

0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.65	GO:0039536	negative regulation of RIG-I signaling pathway
0.64	GO:0032480	negative regulation of type I interferon production
0.63	GO:1903513	endoplasmic reticulum to cytosol transport
0.62	GO:0032527	protein exit from endoplasmic reticulum
0.59	GO:0036503	ERAD pathway

0.51	GO:0046872	metal ion binding
0.50	GO:0043130	ubiquitin binding
0.49	GO:0031625	ubiquitin protein ligase binding

0.67	GO:0036501	UFD1-NPL4 complex
0.63	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex
0.42	GO:0005634	nucleus

tr|T1FMC4|T1FMC4_HELRO
Calcium-transporting ATPase
Search

0.60	Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type

0.76	GO:0070588	calcium ion transmembrane transport
0.68	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.40	GO:0006874	cellular calcium ion homeostasis
0.40	GO:0090076	relaxation of skeletal muscle
0.39	GO:0031446	regulation of fast-twitch skeletal muscle fiber contraction
0.39	GO:0051659	maintenance of mitochondrion location
0.39	GO:0045989	positive regulation of striated muscle contraction
0.38	GO:1901896	positive regulation of calcium-transporting ATPase activity
0.38	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
0.38	GO:0007629	flight behavior

0.80	GO:0005388	calcium-transporting ATPase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0008144	drug binding
0.36	GO:0042803	protein homodimerization activity
0.36	GO:0005509	calcium ion binding
0.34	GO:0004652	polynucleotide adenylyltransferase activity

0.45	GO:0016529	sarcoplasmic reticulum
0.42	GO:0005789	endoplasmic reticulum membrane
0.41	GO:0098588	bounding membrane of organelle
0.34	GO:0005739	mitochondrion
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.80

EC:3.6.3.8

GO:0005388

tr|T1FMC5|T1FMC5_HELRO
Uncharacterized protein
Search

ZNF367

0.43	Zinc finger protein 367

0.46	GO:0006357	regulation of transcription by RNA polymerase II
0.34	GO:0006351	transcription, DNA-templated
0.33	GO:0006468	protein phosphorylation

0.51	GO:0003676	nucleic acid binding
0.42	GO:0003700	DNA binding transcription factor activity
0.34	GO:0046872	metal ion binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.46

GO:0005654

nucleoplasm

tr|T1FMC6|T1FMC6_HELRO
Uncharacterized protein
Search

PHB2

0.62	Prohibitin

0.47	GO:0033600	negative regulation of mammary gland epithelial cell proliferation
0.47	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis
0.46	GO:0060744	mammary gland branching involved in thelarche
0.46	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway
0.46	GO:0031536	positive regulation of exit from mitosis
0.45	GO:0061377	mammary gland lobule development
0.45	GO:0000060	protein import into nucleus, translocation
0.45	GO:1902808	positive regulation of cell cycle G1/S phase transition
0.44	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.44	GO:0043433	negative regulation of DNA binding transcription factor activity

0.45	GO:0047485	protein N-terminus binding
0.44	GO:0008022	protein C-terminus binding
0.41	GO:0033218	amide binding

0.45	GO:0016363	nuclear matrix
0.43	GO:0005741	mitochondrial outer membrane
0.42	GO:0009986	cell surface
0.39	GO:0019866	organelle inner membrane
0.38	GO:0043234	protein complex
0.37	GO:0071944	cell periphery
0.35	GO:0030424	axon
0.35	GO:0031982	vesicle
0.34	GO:0043230	extracellular organelle
0.33	GO:0005615	extracellular space

tr|T1FMC7|T1FMC7_HELRO
Triosephosphate isomerase
Search

0.45	Triosephosphate isomerase A

0.69	GO:0006757	ATP generation from ADP
0.69	GO:0019319	hexose biosynthetic process
0.68	GO:0006098	pentose-phosphate shunt
0.67	GO:0006090	pyruvate metabolic process
0.67	GO:0006006	glucose metabolic process
0.66	GO:0016052	carbohydrate catabolic process
0.43	GO:0046166	glyceraldehyde-3-phosphate biosynthetic process
0.40	GO:0046174	polyol catabolic process
0.40	GO:0006071	glycerol metabolic process
0.37	GO:0044248	cellular catabolic process

0.77	GO:0004807	triose-phosphate isomerase activity
0.34	GO:0042802	identical protein binding

0.38	GO:0005829	cytosol
0.36	GO:0020015	glycosome

0.77	EC:5.3.1.1	GO:0004807
0.77	KEGG:R01015	GO:0004807

tr|T1FMC8|T1FMC8_HELRO
Uncharacterized protein
Search

0.45	Intestinal-type alkaline phosphatase

0.68	GO:0016311	dephosphorylation
0.35	GO:0033280	response to vitamin D
0.33	GO:0007165	signal transduction

0.76	GO:0004035	alkaline phosphatase activity
0.33	GO:0005509	calcium ion binding
0.32	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

0.36	GO:0009986	cell surface
0.34	GO:0005578	proteinaceous extracellular matrix
0.30	GO:0031224	intrinsic component of membrane

0.76

EC:3.1.3.1

GO:0004035

tr|T1FMC9|T1FMC9_HELRO
Uncharacterized protein
Search

0.52	GO:1905949	negative regulation of calcium ion import across plasma membrane
0.52	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.47	GO:0042327	positive regulation of phosphorylation
0.41	GO:0043085	positive regulation of catalytic activity
0.41	GO:0009966	regulation of signal transduction

0.70	GO:0005509	calcium ion binding
0.53	GO:0098744	1-phosphatidylinositol 4-kinase activator activity

0.42	GO:0000139	Golgi membrane
0.40	GO:0005886	plasma membrane

tr|T1FMD0|T1FMD0_HELRO
Uncharacterized protein
Search

tr|T1FMD1|T1FMD1_HELRO
Uncharacterized protein
Search

tr|T1FMD2|T1FMD2_HELRO
Uncharacterized protein
Search

0.56	Non-muscle actin II

0.53	GO:0030554	adenyl nucleotide binding
0.52	GO:0097367	carbohydrate derivative binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding

0.43	GO:0005856	cytoskeleton
0.36	GO:0005737	cytoplasm
0.34	GO:0005925	focal adhesion
0.33	GO:0005634	nucleus
0.33	GO:0043234	protein complex
0.32	GO:0005886	plasma membrane

tr|T1FMD3|T1FMD3_HELRO
Uncharacterized protein
Search

RAB4A

0.83	RAB4B member RAS oncogene family

0.64	GO:0030100	regulation of endocytosis
0.57	GO:0019882	antigen processing and presentation
0.50	GO:0015031	protein transport
0.46	GO:0001944	vasculature development
0.39	GO:0032482	Rab protein signal transduction
0.38	GO:0032781	positive regulation of ATPase activity

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008565	protein transporter activity
0.39	GO:0035255	ionotropic glutamate receptor binding
0.38	GO:0051117	ATPase binding
0.38	GO:0019905	syntaxin binding
0.38	GO:0001671	ATPase activator activity

0.60	GO:0070062	extracellular exosome
0.60	GO:0005768	endosome
0.59	GO:0048471	perinuclear region of cytoplasm
0.56	GO:0032593	insulin-responsive compartment
0.37	GO:0098794	postsynapse
0.36	GO:0005829	cytosol
0.34	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1FMD4|T1FMD4_HELRO
Uncharacterized protein
Search

0.65	Alpha/beta hydrolase domain-containing protein 17C

0.53	GO:0098734	macromolecule depalmitoylation
0.51	GO:0018345	protein palmitoylation
0.50	GO:1902816	regulation of protein localization to microtubule
0.49	GO:1905668	positive regulation of protein localization to endosome
0.48	GO:0042159	lipoprotein catabolic process
0.47	GO:1903828	negative regulation of cellular protein localization
0.45	GO:0035601	protein deacylation
0.39	GO:0072657	protein localization to membrane
0.33	GO:0006508	proteolysis

0.53	GO:0008474	palmitoyl-(protein) hydrolase activity
0.34	GO:0008236	serine-type peptidase activity

0.47	GO:0014069	postsynaptic density
0.40	GO:0010008	endosome membrane
0.36	GO:0005886	plasma membrane

0.53

EC:3.1.2.22

GO:0008474

tr|T1FMD5|T1FMD5_HELRO
Uncharacterized protein
Search

RFC4

0.59	Replication factor C subunit

0.65	GO:0006260	DNA replication
0.54	GO:1900264	positive regulation of DNA-directed DNA polymerase activity
0.43	GO:0006281	DNA repair
0.42	GO:0000076	DNA replication checkpoint
0.42	GO:0022616	DNA strand elongation
0.41	GO:0044818	mitotic G2/M transition checkpoint
0.40	GO:0034644	cellular response to UV
0.40	GO:0044774	mitotic DNA integrity checkpoint
0.40	GO:0060041	retina development in camera-type eye
0.36	GO:0010172	embryonic body morphogenesis

0.55	GO:0003689	DNA clamp loader activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0043142	single-stranded DNA-dependent ATPase activity
0.46	GO:0019899	enzyme binding
0.39	GO:0003682	chromatin binding
0.35	GO:0045296	cadherin binding
0.33	GO:0003887	DNA-directed DNA polymerase activity

0.55	GO:0005663	DNA replication factor C complex
0.52	GO:0031390	Ctf18 RFC-like complex
0.48	GO:0031391	Elg1 RFC-like complex
0.47	GO:0031981	nuclear lumen
0.36	GO:0031389	Rad17 RFC-like complex
0.35	GO:0005913	cell-cell adherens junction
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0003887

tr|T1FMD6|T1FMD6_HELRO
Uncharacterized protein
Search

FBXO16

0.97	F-box only protein 16

tr|T1FMD7|T1FMD7_HELRO
Uncharacterized protein
Search

SLC25A46

0.89	Solute carrier family 25 member 46

0.55	GO:0090149	mitochondrial membrane fission
0.35	GO:0061564	axon development
0.34	GO:0006430	lysyl-tRNA aminoacylation
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.34	GO:0004824	lysine-tRNA ligase activity
0.33	GO:0003676	nucleic acid binding
0.33	GO:0005515	protein binding
0.33	GO:0008270	zinc ion binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.50	GO:0005741	mitochondrial outer membrane
0.35	GO:0043005	neuron projection
0.34	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:6.1.1.6

GO:0004824

tr|T1FMD8|T1FMD8_HELRO
Tetraspanin
Search

0.51	Tetraspanin

0.30

GO:0044425

membrane part

tr|T1FMD9|T1FMD9_HELRO
Uncharacterized protein
Search

0.46	RAB35 member RAS oncogene family

0.45	GO:0032456	endocytic recycling
0.45	GO:0019882	antigen processing and presentation
0.44	GO:0000281	mitotic cytokinesis
0.43	GO:0017157	regulation of exocytosis
0.43	GO:0048227	plasma membrane to endosome transport
0.42	GO:0036010	protein localization to endosome
0.42	GO:1990182	exosomal secretion
0.40	GO:0031175	neuron projection development
0.35	GO:0015031	protein transport
0.35	GO:0032482	Rab protein signal transduction

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0031489	myosin V binding
0.45	GO:0030742	GTP-dependent protein binding
0.41	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.35	GO:0071532	ankyrin repeat binding
0.35	GO:0032794	GTPase activating protein binding

0.47	GO:0031410	cytoplasmic vesicle
0.45	GO:0012505	endomembrane system
0.43	GO:0098805	whole membrane
0.43	GO:0098793	presynapse
0.42	GO:0048471	perinuclear region of cytoplasm
0.42	GO:0098588	bounding membrane of organelle
0.41	GO:0045171	intercellular bridge
0.41	GO:0031253	cell projection membrane
0.38	GO:0044446	intracellular organelle part
0.37	GO:0005739	mitochondrion

tr|T1FME0|T1FME0_HELRO
Uncharacterized protein
Search

tr|T1FME1|T1FME1_HELRO
Uncharacterized protein
Search

GTF2H2

0.89	General transcription factor IIH polypeptide 2

0.73	GO:0006289	nucleotide-excision repair
0.58	GO:0006351	transcription, DNA-templated
0.44	GO:0006357	regulation of transcription by RNA polymerase II
0.36	GO:0002031	G-protein coupled receptor internalization
0.36	GO:0006468	protein phosphorylation
0.35	GO:0016567	protein ubiquitination
0.35	GO:0071824	protein-DNA complex subunit organization
0.34	GO:0034367	macromolecular complex remodeling
0.34	GO:0006359	regulation of transcription by RNA polymerase III
0.34	GO:0009411	response to UV

0.62	GO:0008270	zinc ion binding
0.50	GO:0003676	nucleic acid binding
0.38	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity
0.36	GO:0047485	protein N-terminus binding
0.36	GO:0008094	DNA-dependent ATPase activity
0.35	GO:0061630	ubiquitin protein ligase activity
0.34	GO:0000990	transcription factor activity, core RNA polymerase binding
0.34	GO:0001007	transcription factor activity, RNA polymerase III transcription factor binding
0.34	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.33	GO:0016874	ligase activity

0.81	GO:0000439	core TFIIH complex
0.51	GO:0005675	holo TFIIH complex
0.37	GO:0000112	nucleotide-excision repair factor 3 complex
0.36	GO:0016607	nuclear speck
0.35	GO:0005669	transcription factor TFIID complex
0.34	GO:0000126	transcription factor TFIIIB complex
0.30	GO:0016021	integral component of membrane

0.38

EC:2.7.11.23

GO:0008353

tr|T1FME2|T1FME2_HELRO
Uncharacterized protein
Search

0.55	Rab small monomeric gtpase

0.47	GO:0032889	regulation of vacuole fusion, non-autophagic
0.46	GO:0007033	vacuole organization
0.46	GO:0060627	regulation of vesicle-mediated transport
0.46	GO:0034727	piecemeal microautophagy of the nucleus
0.46	GO:0016197	endosomal transport
0.45	GO:0048284	organelle fusion
0.45	GO:0044090	positive regulation of vacuole organization
0.45	GO:0048308	organelle inheritance
0.45	GO:0016236	macroautophagy
0.45	GO:0032258	protein localization by the Cvt pathway

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0008832	dGTPase activity
0.34	GO:0004363	glutathione synthase activity
0.33	GO:0005200	structural constituent of cytoskeleton
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0008144	drug binding

0.47	GO:0000323	lytic vacuole
0.46	GO:1990816	vacuole-mitochondrion membrane contact site
0.45	GO:0030906	retromer, cargo-selective complex
0.45	GO:0000322	storage vacuole
0.45	GO:0098805	whole membrane
0.44	GO:0044437	vacuolar part
0.44	GO:0098588	bounding membrane of organelle
0.41	GO:0005829	cytosol
0.41	GO:0045335	phagocytic vesicle
0.39	GO:0005770	late endosome

0.36	EC:3.1.5.1	GO:0008832
0.36	KEGG:R01856	GO:0008832

tr|T1FME3|T1FME3_HELRO
Uncharacterized protein
Search

0.79	Calcineurin B homologous protein 2

0.70

GO:0005509

calcium ion binding

tr|T1FME4|T1FME4_HELRO
Uncharacterized protein
Search

0.11

Calponin

0.81	GO:0031032	actomyosin structure organization
0.37	GO:0001300	chronological cell aging
0.36	GO:0007015	actin filament organization
0.33	GO:0006351	transcription, DNA-templated
0.33	GO:2001141	regulation of RNA biosynthetic process
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.76	GO:0005516	calmodulin binding
0.73	GO:0003779	actin binding
0.36	GO:0030674	protein binding, bridging
0.36	GO:0032403	protein complex binding
0.34	GO:0008270	zinc ion binding
0.34	GO:0003677	DNA binding

0.37	GO:0030479	actin cortical patch
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

tr|T1FME5|T1FME5_HELRO
Uncharacterized protein
Search

LOC106159561

0.90	Erythrocyte band 7 integral membrane protein

0.35

GO:0005887

integral component of plasma membrane

tr|T1FME7|T1FME7_HELRO
Uncharacterized protein
Search

0.55	Cytoplasmic actin

0.39	GO:0000281	mitotic cytokinesis
0.38	GO:0007111	meiosis II cytokinesis
0.37	GO:0030866	cortical actin cytoskeleton organization
0.37	GO:0009792	embryo development ending in birth or egg hatching
0.35	GO:0040011	locomotion

0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding

0.41	GO:0005856	cytoskeleton
0.37	GO:0035060	brahma complex
0.36	GO:0005938	cell cortex
0.36	GO:0099512	supramolecular fiber
0.32	GO:0005886	plasma membrane

tr|T1FME8|T1FME8_HELRO
Uncharacterized protein
Search

0.39	Orotate phosphoribosyltransferase

0.74	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process
0.73	GO:0044205	'de novo' UMP biosynthetic process
0.40	GO:0046686	response to cadmium ion
0.40	GO:0016036	cellular response to phosphate starvation
0.34	GO:0006420	arginyl-tRNA aminoacylation
0.33	GO:0006468	protein phosphorylation

0.78	GO:0004590	orotidine-5'-phosphate decarboxylase activity
0.77	GO:0004588	orotate phosphoribosyltransferase activity
0.34	GO:0000287	magnesium ion binding
0.34	GO:0004814	arginine-tRNA ligase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0004672	protein kinase activity

0.37	GO:0005829	cytosol
0.36	GO:0005634	nucleus
0.34	GO:0045335	phagocytic vesicle

0.78	EC:4.1.1.23	GO:0004590
0.78	KEGG:R00965	GO:0004590

tr|T1FME9|T1FME9_HELRO
Lipoyl synthase, mitochondrial
Search

LIAS

0.72	Lipoyl synthase, mitochondrial

0.79	GO:0009107	lipoate biosynthetic process
0.74	GO:0009249	protein lipoylation
0.45	GO:0001843	neural tube closure
0.44	GO:0032496	response to lipopolysaccharide
0.44	GO:0006954	inflammatory response
0.41	GO:0006979	response to oxidative stress
0.33	GO:0006260	DNA replication
0.33	GO:0055085	transmembrane transport
0.33	GO:0006468	protein phosphorylation
0.32	GO:0055114	oxidation-reduction process

0.80	GO:0016992	lipoate synthase activity
0.67	GO:0051539	4 iron, 4 sulfur cluster binding
0.52	GO:0046872	metal ion binding
0.34	GO:0061731	ribonucleoside-diphosphate reductase activity
0.33	GO:0022857	transmembrane transporter activity
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0032553	ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0004672	protein kinase activity

0.57	GO:0005739	mitochondrion
0.44	GO:0009507	chloroplast
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.80

EC:2.8.1.8

GO:0016992

tr|T1FMF0|T1FMF0_HELRO
Uncharacterized protein
Search

tr|T1FMF1|T1FMF1_HELRO
Uncharacterized protein
Search

0.71	Mps one binder kinase activator

0.54	GO:0016310	phosphorylation
0.50	GO:0031952	regulation of protein autophosphorylation
0.49	GO:0035329	hippo signaling
0.49	GO:0030707	ovarian follicle cell development
0.47	GO:0008283	cell proliferation
0.47	GO:0006915	apoptotic process
0.46	GO:0042327	positive regulation of phosphorylation
0.45	GO:0007059	chromosome segregation
0.44	GO:0007275	multicellular organism development
0.34	GO:0036211	protein modification process

0.57	GO:0016301	kinase activity
0.53	GO:0019900	kinase binding
0.48	GO:0019209	kinase activator activity
0.35	GO:0046872	metal ion binding
0.34	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.33	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.49	GO:0005829	cytosol
0.47	GO:0005813	centrosome
0.45	GO:0005634	nucleus
0.43	GO:0043233	organelle lumen
0.39	GO:0005886	plasma membrane
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0016773

tr|T1FMF2|T1FMF2_HELRO
Uncharacterized protein
Search

SEPT7

0.80	Putative septin family protein p-loop gtpase

0.42	GO:0000281	mitotic cytokinesis
0.42	GO:0043065	positive regulation of apoptotic process
0.42	GO:0006915	apoptotic process
0.41	GO:0072114	pronephros morphogenesis
0.39	GO:0060271	cilium assembly
0.35	GO:0090163	establishment of epithelial cell planar polarity
0.35	GO:0060031	mediolateral intercalation
0.35	GO:0016476	regulation of embryonic cell shape
0.34	GO:0007349	cellularization
0.34	GO:0044837	actomyosin contractile ring organization

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0031625	ubiquitin protein ligase binding
0.41	GO:0042803	protein homodimerization activity
0.41	GO:0008017	microtubule binding
0.41	GO:0003779	actin binding
0.39	GO:0003924	GTPase activity
0.33	GO:0003677	DNA binding

0.72	GO:0031105	septin complex
0.44	GO:0032154	cleavage furrow
0.43	GO:0045171	intercellular bridge
0.43	GO:0070938	contractile ring
0.37	GO:0005886	plasma membrane
0.35	GO:0045177	apical part of cell
0.34	GO:0030496	midbody
0.34	GO:0005930	axoneme
0.34	GO:0005940	septin ring
0.34	GO:0000777	condensed chromosome kinetochore

tr|T1FMF3|T1FMF3_HELRO
Eukaryotic translation initiation factor 3 subunit F
Search

EIF3F

0.74	Eukaryotic translation initiation factor 3 subunit F

0.73	GO:0001731	formation of translation preinitiation complex
0.72	GO:0006446	regulation of translational initiation
0.50	GO:0075522	IRES-dependent viral translational initiation
0.46	GO:0016579	protein deubiquitination
0.43	GO:1904888	cranial skeletal system development

0.72	GO:0003743	translation initiation factor activity
0.51	GO:0031369	translation initiation factor binding
0.47	GO:0004843	thiol-dependent ubiquitin-specific protease activity

0.78	GO:0005852	eukaryotic translation initiation factor 3 complex
0.72	GO:0016282	eukaryotic 43S preinitiation complex
0.72	GO:0033290	eukaryotic 48S preinitiation complex
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

tr|T1FMF4|T1FMF4_HELRO
Uncharacterized protein
Search

RDH14

0.52	Retinol dehydrogenase

0.55	GO:0042572	retinol metabolic process
0.44	GO:0055114	oxidation-reduction process
0.39	GO:0001649	osteoblast differentiation
0.37	GO:0010842	retina layer formation
0.37	GO:0009314	response to radiation
0.37	GO:0042462	eye photoreceptor cell development
0.35	GO:0050829	defense response to Gram-negative bacterium
0.35	GO:2000377	regulation of reactive oxygen species metabolic process
0.35	GO:0016311	dephosphorylation
0.34	GO:0019290	siderophore biosynthetic process

0.55	GO:0008106	alcohol dehydrogenase (NADP+) activity
0.37	GO:0016630	protochlorophyllide reductase activity
0.36	GO:0008253	5'-nucleotidase activity
0.34	GO:0000287	magnesium ion binding
0.34	GO:0008667	2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity
0.34	GO:1901265	nucleoside phosphate binding
0.34	GO:0005509	calcium ion binding
0.33	GO:0036094	small molecule binding
0.33	GO:0097367	carbohydrate derivative binding
0.33	GO:0008144	drug binding

0.47	GO:0005783	endoplasmic reticulum
0.44	GO:0005739	mitochondrion
0.40	GO:0005765	lysosomal membrane
0.35	GO:0005634	nucleus
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.55	EC:1.1.1.2	GO:0008106
0.34	KEGG:R01505	GO:0008667

tr|T1FMF5|T1FMF5_HELRO
Histone H3
Search

tr|T1FMF6|T1FMF6_HELRO
Uncharacterized protein
Search

0.62	Neuron-specific calcium-binding protein hippocalcin (Fragment)

0.44	GO:1901385	regulation of voltage-gated calcium channel activity
0.44	GO:0071277	cellular response to calcium ion
0.43	GO:0048839	inner ear development
0.40	GO:0016310	phosphorylation
0.39	GO:0036211	protein modification process
0.38	GO:0009738	abscisic acid-activated signaling pathway
0.37	GO:0044267	cellular protein metabolic process
0.35	GO:0035556	intracellular signal transduction

0.70	GO:0005509	calcium ion binding
0.41	GO:0016301	kinase activity
0.41	GO:0042802	identical protein binding
0.41	GO:0003779	actin binding
0.40	GO:0016746	transferase activity, transferring acyl groups
0.39	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.38	GO:0140096	catalytic activity, acting on a protein
0.37	GO:0005516	calmodulin binding
0.37	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0008144	drug binding

0.35	GO:0005737	cytoplasm
0.35	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.40

EC:2.3

GO:0016746

tr|T1FMF7|T1FMF7_HELRO
Uncharacterized protein
Search

0.49	N-acetylated-alpha-linked acidic dipeptidase 2

0.53	GO:0042135	neurotransmitter catabolic process
0.45	GO:0006508	proteolysis

0.60	GO:0050129	N-formylglutamate deformylase activity
0.51	GO:0004180	carboxypeptidase activity

0.30

GO:0031224

intrinsic component of membrane

0.60	EC:3.5.1.68	GO:0050129
0.60	KEGG:R00525	GO:0050129

tr|T1FMF8|T1FMF8_HELRO
Uncharacterized protein
Search

SEPT6

0.84	Septin-6 isoform D

0.46	GO:0035469	determination of pancreatic left/right asymmetry
0.46	GO:0071910	determination of liver left/right asymmetry
0.46	GO:0003140	determination of left/right asymmetry in lateral mesoderm
0.46	GO:0071907	determination of digestive tract left/right asymmetry
0.44	GO:0061371	determination of heart left/right asymmetry
0.43	GO:0060271	cilium assembly
0.38	GO:0051291	protein heterooligomerization
0.37	GO:0051301	cell division
0.37	GO:0007049	cell cycle
0.35	GO:0007283	spermatogenesis

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding

0.75	GO:0031105	septin complex
0.46	GO:0120025	plasma membrane bounded cell projection
0.44	GO:0032173	septin collar
0.43	GO:0032154	cleavage furrow
0.42	GO:0005940	septin ring
0.42	GO:0097223	sperm part
0.42	GO:0044456	synapse part
0.42	GO:0097458	neuron part
0.42	GO:0070382	exocytic vesicle
0.40	GO:0044463	cell projection part

tr|T1FMF9|T1FMF9_HELRO
Ribosomal protein L19
Search

0.67	Ribosomal protein L19

0.60	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.34	GO:0008340	determination of adult lifespan
0.33	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic

0.64	GO:0003735	structural constituent of ribosome
0.36	GO:0003723	RNA binding
0.34	GO:0004523	RNA-DNA hybrid ribonuclease activity

0.77

GO:0022625

cytosolic large ribosomal subunit

0.34

EC:3.1.26.4

GO:0004523

tr|T1FMG0|T1FMG0_HELRO
Uncharacterized protein
Search

TXNL1

0.58	Z-linked thioredoxin like 1

0.66	GO:0045454	cell redox homeostasis
0.44	GO:0034599	cellular response to oxidative stress
0.42	GO:0098869	cellular oxidant detoxification
0.41	GO:0055114	oxidation-reduction process
0.35	GO:0006662	glycerol ether metabolic process

0.50	GO:0015036	disulfide oxidoreductase activity
0.44	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
0.44	GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor
0.42	GO:0016209	antioxidant activity

0.48	GO:0005829	cytosol
0.37	GO:1905369	endopeptidase complex
0.37	GO:0070062	extracellular exosome
0.35	GO:0005634	nucleus
0.35	GO:0043234	protein complex

0.44

EC:1.8.4

GO:0016671

tr|T1FMG1|T1FMG1_HELRO
Uncharacterized protein
Search

RPF1

0.91	Ribosome production factor 1

0.64	GO:0000470	maturation of LSU-rRNA
0.64	GO:0000460	maturation of 5.8S rRNA
0.61	GO:0000027	ribosomal large subunit assembly
0.38	GO:0000055	ribosomal large subunit export from nucleus
0.37	GO:0009793	embryo development ending in seed dormancy

0.68	GO:0042134	rRNA primary transcript binding
0.35	GO:0005515	protein binding

0.71	GO:0005730	nucleolus
0.63	GO:0030687	preribosome, large subunit precursor
0.41	GO:0019013	viral nucleocapsid
0.38	GO:0005829	cytosol
0.30	GO:0016020	membrane

tr|T1FMG2|T1FMG2_HELRO
Uncharacterized protein
Search

tr|T1FMG3|T1FMG3_HELRO
Uncharacterized protein
Search

TMED7

0.90	Transmembrane emp24 protein transport domain containing 7

0.38	GO:0007165	signal transduction
0.36	GO:2000494	positive regulation of interleukin-18-mediated signaling pathway
0.35	GO:0015031	protein transport
0.35	GO:0071651	positive regulation of chemokine (C-C motif) ligand 5 production
0.35	GO:0070671	response to interleukin-12
0.35	GO:0034145	positive regulation of toll-like receptor 4 signaling pathway
0.35	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.35	GO:0032729	positive regulation of interferon-gamma production
0.35	GO:0006888	ER to Golgi vesicle-mediated transport
0.35	GO:0032755	positive regulation of interleukin-6 production

0.34	GO:0005543	phospholipid binding
0.33	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.33	GO:0004450	isocitrate dehydrogenase (NADP+) activity
0.33	GO:0005506	iron ion binding
0.32	GO:0051287	NAD binding
0.32	GO:0000287	magnesium ion binding

0.49	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.45	GO:0005794	Golgi apparatus
0.44	GO:0005783	endoplasmic reticulum
0.38	GO:0030663	COPI-coated vesicle membrane
0.37	GO:0030120	vesicle coat
0.36	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0031984	organelle subcompartment
0.36	GO:0030133	transport vesicle
0.35	GO:0070062	extracellular exosome
0.35	GO:0030134	COPII-coated ER to Golgi transport vesicle

0.33

EC:1.13.11

GO:0016702

tr|T1FMG4|T1FMG4_HELRO
Uncharacterized protein
Search

COPS5

0.83	C-Jun activation domain binding protein-1

0.59	GO:0006508	proteolysis
0.57	GO:1990182	exosomal secretion
0.57	GO:1903894	regulation of IRE1-mediated unfolded protein response
0.54	GO:0051091	positive regulation of DNA binding transcription factor activity
0.53	GO:0046328	regulation of JNK cascade
0.52	GO:0043066	negative regulation of apoptotic process
0.50	GO:0045944	positive regulation of transcription by RNA polymerase II
0.49	GO:0051726	regulation of cell cycle
0.48	GO:0070647	protein modification by small protein conjugation or removal
0.37	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c

0.68	GO:0004222	metalloendopeptidase activity
0.59	GO:0035718	macrophage migration inhibitory factor binding
0.52	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.48	GO:0019899	enzyme binding
0.36	GO:0003713	transcription coactivator activity
0.35	GO:0019784	NEDD8-specific protease activity
0.34	GO:0046872	metal ion binding
0.34	GO:0046983	protein dimerization activity
0.34	GO:0003743	translation initiation factor activity

0.79	GO:0008180	COP9 signalosome
0.54	GO:0008021	synaptic vesicle
0.48	GO:0000785	chromatin
0.48	GO:0005829	cytosol
0.47	GO:0005654	nucleoplasm
0.39	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0030054	cell junction
0.34	GO:0005852	eukaryotic translation initiation factor 3 complex
0.34	GO:0005667	transcription factor complex
0.34	GO:0005739	mitochondrion

0.68

GO:0004222

tr|T1FMG5|T1FMG5_HELRO
Uncharacterized protein
Search

0.39	Cathepsin L proteinase

0.61	GO:0006508	proteolysis
0.38	GO:0044257	cellular protein catabolic process
0.35	GO:0097067	cellular response to thyroid hormone stimulus
0.34	GO:0010839	negative regulation of keratinocyte proliferation
0.34	GO:0046697	decidualization
0.34	GO:0031069	hair follicle morphogenesis
0.34	GO:0030574	collagen catabolic process
0.34	GO:2000249	regulation of actin cytoskeleton reorganization
0.34	GO:0002250	adaptive immune response
0.33	GO:0006415	translational termination

0.72	GO:0008234	cysteine-type peptidase activity
0.37	GO:0004175	endopeptidase activity
0.35	GO:0042393	histone binding
0.35	GO:0097655	serpin family protein binding
0.34	GO:0001968	fibronectin binding
0.34	GO:0043394	proteoglycan binding
0.34	GO:0005518	collagen binding
0.33	GO:0003747	translation release factor activity
0.33	GO:0004180	carboxypeptidase activity
0.33	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups

0.41	GO:0005764	lysosome
0.39	GO:0005615	extracellular space
0.35	GO:0045169	fusome
0.33	GO:0005730	nucleolus
0.33	GO:0031410	cytoplasmic vesicle
0.30	GO:0016020	membrane

0.72

GO:0008234

tr|T1FMG6|T1FMG6_HELRO
Uncharacterized protein
Search

0.60	Digestive cysteine protease

0.61	GO:0006508	proteolysis
0.39	GO:0044257	cellular protein catabolic process
0.38	GO:0010839	negative regulation of keratinocyte proliferation
0.38	GO:0046697	decidualization
0.38	GO:0031069	hair follicle morphogenesis
0.38	GO:2000249	regulation of actin cytoskeleton reorganization
0.36	GO:0051604	protein maturation
0.34	GO:0007586	digestion

0.72	GO:0008234	cysteine-type peptidase activity
0.37	GO:0004175	endopeptidase activity
0.37	GO:0042393	histone binding
0.36	GO:0004180	carboxypeptidase activity
0.33	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.42	GO:0005764	lysosome
0.41	GO:0005615	extracellular space
0.36	GO:0005730	nucleolus
0.36	GO:0031410	cytoplasmic vesicle
0.35	GO:0045169	fusome
0.30	GO:0016020	membrane

0.72

GO:0008234

tr|T1FMG7|T1FMG7_HELRO
Uncharacterized protein
Search

0.51	GO:0035297	regulation of Malpighian tubule diameter
0.50	GO:0048567	ectodermal digestive tract morphogenesis
0.50	GO:0007390	germ-band shortening
0.49	GO:0035262	gonad morphogenesis
0.49	GO:0046329	negative regulation of JNK cascade
0.49	GO:0007391	dorsal closure
0.48	GO:0007435	salivary gland morphogenesis
0.46	GO:0007417	central nervous system development
0.43	GO:0008360	regulation of cell shape
0.41	GO:0008104	protein localization

0.67	GO:0005509	calcium ion binding
0.36	GO:0004559	alpha-mannosidase activity
0.33	GO:0016740	transferase activity

0.38	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.36

EC:3.2.1.24

GO:0004559

tr|T1FMG8|T1FMG8_HELRO
Tubulin alpha chain
Search

0.53	Tubulin alpha chain

0.71	GO:0007017	microtubule-based process
0.71	GO:0007010	cytoskeleton organization
0.34	GO:0030705	cytoskeleton-dependent intracellular transport
0.33	GO:0051301	cell division

0.76	GO:0005200	structural constituent of cytoskeleton
0.67	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.53	GO:0032553	ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005515	protein binding

0.73	GO:0005874	microtubule
0.47	GO:0005737	cytoplasm
0.35	GO:0031982	vesicle
0.34	GO:0005634	nucleus
0.34	GO:0098857	membrane microdomain

tr|T1FMG9|T1FMG9_HELRO
Uncharacterized protein
Search

EIPR1

0.93	EARP complex and GARP complex interacting protein 1

tr|T1FMH0|T1FMH0_HELRO
Uncharacterized protein
Search

DDX47

0.62	Apolipoprotein-L domain-containing protein 1

0.53	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors
0.47	GO:0008380	RNA splicing
0.46	GO:0006364	rRNA processing
0.44	GO:0010501	RNA secondary structure unwinding
0.35	GO:0006397	mRNA processing
0.33	GO:0035556	intracellular signal transduction
0.33	GO:0006508	proteolysis

0.67	GO:0004386	helicase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0003676	nucleic acid binding
0.43	GO:0008186	RNA-dependent ATPase activity
0.39	GO:0140098	catalytic activity, acting on RNA
0.33	GO:0008234	cysteine-type peptidase activity
0.33	GO:0005515	protein binding

0.48	GO:0005730	nucleolus
0.35	GO:0005737	cytoplasm
0.33	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0008234

tr|T1FMH1|T1FMH1_HELRO
Diphosphomevalonate decarboxylase
Search

MVD

0.60	Diphosphomevalonate decarboxylase

0.83	GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway
0.76	GO:0006695	cholesterol biosynthetic process
0.46	GO:0008284	positive regulation of cell proliferation
0.36	GO:0045454	cell redox homeostasis
0.35	GO:0006489	dolichyl diphosphate biosynthetic process
0.35	GO:0009889	regulation of biosynthetic process
0.35	GO:0080090	regulation of primary metabolic process
0.34	GO:0010468	regulation of gene expression
0.34	GO:0031323	regulation of cellular metabolic process
0.34	GO:0051171	regulation of nitrogen compound metabolic process

0.84	GO:0004163	diphosphomevalonate decarboxylase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0030544	Hsp70 protein binding
0.45	GO:0042803	protein homodimerization activity
0.36	GO:0043565	sequence-specific DNA binding
0.35	GO:0008270	zinc ion binding
0.35	GO:0003700	DNA binding transcription factor activity
0.34	GO:0016301	kinase activity

0.69	GO:0005829	cytosol
0.35	GO:0005777	peroxisome
0.34	GO:0031907	microbody lumen
0.30	GO:0031224	intrinsic component of membrane

0.84	EC:4.1.1.33	GO:0004163
0.84	KEGG:R01121	GO:0004163

tr|T1FMH2|T1FMH2_HELRO
Uncharacterized protein
Search

AQP4

0.51	Water and ammonia transporting aquaporin

0.55	GO:0055085	transmembrane transport
0.39	GO:0006833	water transport
0.35	GO:0006811	ion transport
0.34	GO:0050891	multicellular organismal water homeostasis
0.34	GO:0071346	cellular response to interferon-gamma
0.33	GO:0006863	purine nucleobase transport
0.33	GO:0071320	cellular response to cAMP
0.33	GO:0015837	amine transport
0.33	GO:0015791	polyol transport
0.33	GO:0046689	response to mercury ion

0.69	GO:0022803	passive transmembrane transporter activity
0.39	GO:0005372	water transmembrane transporter activity
0.33	GO:0005345	purine nucleobase transmembrane transporter activity
0.33	GO:0005350	pyrimidine nucleobase transmembrane transporter activity

0.36	GO:0005887	integral component of plasma membrane
0.36	GO:0016323	basolateral plasma membrane
0.34	GO:0009897	external side of plasma membrane
0.34	GO:0005774	vacuolar membrane

tr|T1FMH3|T1FMH3_HELRO
Inhibitor of growth protein
Search

ING4

0.74	Inhibitor of growth protein 4

0.78	GO:0008285	negative regulation of cell proliferation
0.77	GO:0016573	histone acetylation
0.61	GO:0043065	positive regulation of apoptotic process
0.50	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
0.49	GO:0045926	negative regulation of growth
0.48	GO:0007050	cell cycle arrest
0.46	GO:0006915	apoptotic process
0.44	GO:2001233	regulation of apoptotic signaling pathway
0.44	GO:0045892	negative regulation of transcription, DNA-templated
0.43	GO:0006260	DNA replication

0.61	GO:0140034	methylation-dependent protein binding
0.59	GO:0042393	histone binding
0.53	GO:0046872	metal ion binding
0.47	GO:0003713	transcription coactivator activity
0.43	GO:0003682	chromatin binding
0.33	GO:0050660	flavin adenine dinucleotide binding
0.33	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors

0.76	GO:0070776	MOZ/MORF histone acetyltransferase complex
0.47	GO:0045111	intermediate filament cytoskeleton
0.43	GO:0005829	cytosol

0.33

EC:1.1

GO:0016614

tr|T1FMH4|T1FMH4_HELRO
Protein Wnt
Search

tr|T1FMH5|T1FMH5_HELRO
Ubiquitin carboxyl-terminal hydrolase
Search

UCHL3

0.56	Ubiquitin carboxyl-terminal hydrolase

0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.42	GO:1904888	cranial skeletal system development
0.42	GO:0007219	Notch signaling pathway
0.42	GO:0016579	protein deubiquitination

0.79	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.40	GO:0043130	ubiquitin binding
0.32	GO:0016874	ligase activity

0.45	GO:0005622	intracellular
0.35	GO:0043227	membrane-bounded organelle
0.35	GO:0043196	varicosity
0.30	GO:0016020	membrane

0.32

GO:0016874

tr|T1FMH6|T1FMH6_HELRO
Autophagy-related protein 3
Search

0.75	Autophagy-related protein 3

0.77	GO:0006914	autophagy
0.65	GO:0015031	protein transport
0.53	GO:0007033	vacuole organization
0.49	GO:0070925	organelle assembly
0.49	GO:0043653	mitochondrial fragmentation involved in apoptotic process
0.48	GO:0050765	negative regulation of phagocytosis
0.47	GO:1902017	regulation of cilium assembly
0.45	GO:0061726	mitochondrion disassembly
0.45	GO:0005980	glycogen catabolic process
0.45	GO:0009267	cellular response to starvation

0.52	GO:0019776	Atg8 ligase activity
0.50	GO:0019777	Atg12 transferase activity
0.43	GO:0019899	enzyme binding
0.35	GO:0016874	ligase activity

0.50	GO:0000153	cytoplasmic ubiquitin ligase complex
0.48	GO:0005829	cytosol
0.46	GO:0005776	autophagosome

0.35

GO:0016874

tr|T1FMH7|T1FMH7_HELRO
Uncharacterized protein
Search

SARS

0.58	Seryl-tRNA synthetase

0.79	GO:0006434	seryl-tRNA aminoacylation
0.41	GO:1904046	negative regulation of vascular endothelial growth factor production
0.39	GO:0016525	negative regulation of angiogenesis
0.38	GO:0097056	selenocysteinyl-tRNA(Sec) biosynthetic process
0.38	GO:0000122	negative regulation of transcription by RNA polymerase II
0.34	GO:0016259	selenocysteine metabolic process
0.34	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.33	GO:0007166	cell surface receptor signaling pathway
0.33	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:0008033	tRNA processing

0.79	GO:0004828	serine-tRNA ligase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0001046	core promoter sequence-specific DNA binding
0.36	GO:0098619	selenocysteine-tRNA ligase activity
0.34	GO:0042803	protein homodimerization activity
0.33	GO:0004930	G-protein coupled receptor activity
0.33	GO:0005509	calcium ion binding
0.33	GO:0003723	RNA binding

0.49	GO:0005737	cytoplasm
0.35	GO:0005634	nucleus
0.34	GO:0070062	extracellular exosome
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.79

EC:6.1.1.11

GO:0004828

tr|T1FMH8|T1FMH8_HELRO
Uncharacterized protein
Search

0.37	Lipoma HMGIC fusion partner-like 3 protein

0.30

GO:0044425

membrane part

tr|T1FMH9|T1FMH9_HELRO
Uncharacterized protein
Search

0.45	GO:0000492	box C/D snoRNP assembly
0.43	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

0.54	GO:0046872	metal ion binding
0.36	GO:0003676	nucleic acid binding

tr|T1FMI0|T1FMI0_HELRO
Uncharacterized protein
Search

0.73	Transducin beta like 1 X-linked receptor 1

0.73	GO:0016575	histone deacetylation
0.68	GO:1903507	negative regulation of nucleic acid-templated transcription
0.67	GO:0006357	regulation of transcription by RNA polymerase II
0.62	GO:0045444	fat cell differentiation
0.62	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.62	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.57	GO:0051173	positive regulation of nitrogen compound metabolic process
0.57	GO:0010604	positive regulation of macromolecule metabolic process
0.57	GO:0031325	positive regulation of cellular metabolic process
0.57	GO:2000113	negative regulation of cellular macromolecule biosynthetic process

0.77	GO:0003714	transcription corepressor activity
0.61	GO:0008013	beta-catenin binding
0.59	GO:0042393	histone binding
0.57	GO:0003682	chromatin binding
0.57	GO:0044212	transcription regulatory region DNA binding
0.55	GO:0008022	protein C-terminus binding
0.55	GO:0008134	transcription factor binding
0.52	GO:0019904	protein domain specific binding
0.51	GO:0042802	identical protein binding
0.49	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding

0.75	GO:0000118	histone deacetylase complex
0.64	GO:0017053	transcriptional repressor complex
0.60	GO:0005876	spindle microtubule
0.51	GO:0005667	transcription factor complex
0.48	GO:0005700	polytene chromosome
0.43	GO:0019013	viral nucleocapsid
0.40	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016020	membrane

0.46

GO:0004402

tr|T1FMI1|T1FMI1_HELRO
Alkylglycerone-phosphate synthase
Search

AGPS

0.84	Alkylglycerone-phosphate synthase

0.85	GO:0008611	ether lipid biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.34	GO:0043413	macromolecule glycosylation
0.33	GO:0009101	glycoprotein biosynthetic process
0.33	GO:0044267	cellular protein metabolic process
0.33	GO:0036211	protein modification process
0.33	GO:0043043	peptide biosynthetic process
0.32	GO:0010467	gene expression

0.86	GO:0008609	alkylglycerone-phosphate synthase activity
0.66	GO:0050660	flavin adenine dinucleotide binding
0.65	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors
0.34	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity
0.33	GO:0005515	protein binding
0.33	GO:0003735	structural constituent of ribosome
0.33	GO:0046872	metal ion binding

0.76	GO:0005777	peroxisome
0.47	GO:0005730	nucleolus
0.34	GO:0031907	microbody lumen
0.34	GO:0031903	microbody membrane
0.34	GO:0005739	mitochondrion
0.33	GO:0005783	endoplasmic reticulum
0.33	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

0.86

EC:2.5.1.26

GO:0008609

tr|T1FMI2|T1FMI2_HELRO
Uncharacterized protein
Search

0.10	Inosine-uridine preferring nucleoside hydrolase (Fragment)

0.30

GO:0008152

metabolic process

0.53	GO:0016798	hydrolase activity, acting on glycosyl bonds
0.37	GO:0016407	acetyltransferase activity

0.30

GO:0044425

membrane part

0.53

EC:3.2

GO:0016798

tr|T1FMI3|T1FMI3_HELRO
Uncharacterized protein
Search

DNAJA2

0.87	DnaJ subfamily A member

0.68	GO:0006457	protein folding
0.67	GO:0009408	response to heat
0.51	GO:0032781	positive regulation of ATPase activity
0.36	GO:0018885	carbon tetrachloride metabolic process
0.34	GO:0008284	positive regulation of cell proliferation

0.76	GO:0031072	heat shock protein binding
0.70	GO:0051082	unfolded protein binding
0.53	GO:0046872	metal ion binding
0.52	GO:0001671	ATPase activator activity
0.50	GO:0030554	adenyl nucleotide binding
0.50	GO:0051087	chaperone binding
0.49	GO:0097367	carbohydrate derivative binding
0.49	GO:0008144	drug binding
0.49	GO:0035639	purine ribonucleoside triphosphate binding

0.48	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|T1FMI4|T1FMI4_HELRO
Uncharacterized protein
Search

0.40	Adenosine kinase a

0.76	GO:0006166	purine ribonucleoside salvage
0.74	GO:0006167	AMP biosynthetic process
0.51	GO:0016310	phosphorylation
0.43	GO:0046086	adenosine biosynthetic process
0.38	GO:0044262	cellular carbohydrate metabolic process
0.34	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
0.33	GO:0036211	protein modification process
0.32	GO:0044267	cellular protein metabolic process

0.85	GO:0004001	adenosine kinase activity
0.39	GO:0019200	carbohydrate kinase activity
0.35	GO:0008270	zinc ion binding
0.34	GO:0003723	RNA binding
0.34	GO:0004675	transmembrane receptor protein serine/threonine kinase activity
0.34	GO:0004702	signal transducer, downstream of receptor, with serine/threonine kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.38	GO:0005829	cytosol
0.37	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.85

EC:2.7.1.20

GO:0004001

tr|T1FMI5|T1FMI5_HELRO
Uncharacterized protein
Search

DHRS4

0.29	Short-chain dehydrogenase

0.52	GO:0055114	oxidation-reduction process
0.39	GO:0044255	cellular lipid metabolic process
0.38	GO:0072330	monocarboxylic acid biosynthetic process
0.37	GO:0008610	lipid biosynthetic process
0.36	GO:0006081	cellular aldehyde metabolic process

0.53	GO:0016491	oxidoreductase activity
0.40	GO:0004312	fatty acid synthase activity
0.38	GO:0051287	NAD binding

0.38	GO:0042579	microbody
0.35	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.53

GO:0016491

tr|T1FMI6|T1FMI6_HELRO
Uncharacterized protein
Search

NAA10

0.96	N-alpha-acetyltransferase 11, NatA catalytic subunit

0.55	GO:0006474	N-terminal protein amino acid acetylation
0.54	GO:2000719	negative regulation of maintenance of mitotic sister chromatid cohesion, centromeric
0.53	GO:0030920	peptidyl-serine acetylation
0.50	GO:0018200	peptidyl-glutamic acid modification
0.49	GO:0018209	peptidyl-serine modification
0.48	GO:0006475	internal protein amino acid acetylation
0.34	GO:0000398	mRNA splicing, via spliceosome
0.34	GO:0006323	DNA packaging
0.33	GO:0043547	positive regulation of GTPase activity
0.33	GO:0006468	protein phosphorylation

0.68	GO:0008080	N-acetyltransferase activity
0.46	GO:0043022	ribosome binding
0.34	GO:0005515	protein binding
0.34	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.33	GO:0005096	GTPase activator activity
0.33	GO:0016301	kinase activity
0.32	GO:0140096	catalytic activity, acting on a protein
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0003677	DNA binding
0.32	GO:0008144	drug binding

0.59	GO:0031415	NatA complex
0.48	GO:0005829	cytosol
0.45	GO:0005730	nucleolus
0.42	GO:0030529	intracellular ribonucleoprotein complex
0.37	GO:0071339	MLL1 complex
0.36	GO:0048188	Set1C/COMPASS complex
0.30	GO:0016020	membrane

0.68

GO:0008080

tr|T1FMI7|T1FMI7_HELRO
Uncharacterized protein
Search

0.48	Calmodulin-A

0.39	GO:0016061	regulation of light-activated channel activity
0.39	GO:0016060	metarhodopsin inactivation
0.38	GO:0072499	photoreceptor cell axon guidance
0.38	GO:0035071	salivary gland cell autophagic cell death
0.38	GO:0016056	rhodopsin mediated signaling pathway
0.38	GO:0042052	rhabdomere development
0.37	GO:0046716	muscle cell cellular homeostasis
0.37	GO:2001259	positive regulation of cation channel activity
0.37	GO:0030048	actin filament-based movement
0.37	GO:0007099	centriole replication

0.70	GO:0005509	calcium ion binding
0.39	GO:0070855	myosin VI head/neck binding
0.38	GO:0031489	myosin V binding
0.35	GO:0031418	L-ascorbic acid binding
0.34	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.34	GO:0004683	calmodulin-dependent protein kinase activity
0.34	GO:0005506	iron ion binding

0.39	GO:0031476	myosin VI complex
0.38	GO:0031475	myosin V complex
0.38	GO:0016028	rhabdomere
0.38	GO:0072686	mitotic spindle
0.37	GO:0005813	centrosome
0.37	GO:0030496	midbody
0.37	GO:0005814	centriole
0.37	GO:0000922	spindle pole
0.34	GO:0044428	nuclear part
0.33	GO:0005829	cytosol

0.34

GO:0016705

tr|T1FMI8|T1FMI8_HELRO
Isocitrate dehydrogenase [NAD] subunit, mitochondrial
Search

0.63	Isocitrate dehydrogenase [NAD] subunit, mitochondrial

0.69	GO:0006099	tricarboxylic acid cycle
0.43	GO:0035072	ecdysone-mediated induction of salivary gland cell autophagic cell death
0.36	GO:0006734	NADH metabolic process
0.36	GO:0006103	2-oxoglutarate metabolic process
0.35	GO:0006102	isocitrate metabolic process
0.33	GO:0006541	glutamine metabolic process
0.33	GO:0006508	proteolysis

0.83	GO:0004449	isocitrate dehydrogenase (NAD+) activity
0.67	GO:0051287	NAD binding
0.64	GO:0000287	magnesium ion binding
0.34	GO:0004359	glutaminase activity
0.33	GO:0008233	peptidase activity
0.32	GO:0003677	DNA binding

0.59	GO:0005739	mitochondrion
0.39	GO:0031974	membrane-enclosed lumen
0.36	GO:0044446	intracellular organelle part
0.35	GO:0045242	isocitrate dehydrogenase complex (NAD+)
0.33	GO:0005634	nucleus
0.32	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

0.83

EC:1.1.1.41

GO:0004449

tr|T1FMI9|T1FMI9_HELRO
Uncharacterized protein
Search

ELMO1

0.84	Engulfment and cell motility protein 1

0.78	GO:0016477	cell migration
0.70	GO:0006909	phagocytosis
0.63	GO:0030036	actin cytoskeleton organization
0.52	GO:0016601	Rac protein signal transduction
0.50	GO:0099024	plasma membrane invagination
0.44	GO:0065009	regulation of molecular function
0.39	GO:0098609	cell-cell adhesion
0.39	GO:0001946	lymphangiogenesis
0.39	GO:0045766	positive regulation of angiogenesis
0.38	GO:0060271	cilium assembly

0.48	GO:0017124	SH3 domain binding
0.46	GO:0005085	guanyl-nucleotide exchange factor activity
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0046983	protein dimerization activity
0.32	GO:0003700	DNA binding transcription factor activity
0.32	GO:0003677	DNA binding

0.51	GO:0032045	guanyl-nucleotide exchange factor complex
0.39	GO:0005886	plasma membrane
0.37	GO:0005737	cytoplasm
0.34	GO:0005634	nucleus
0.32	GO:0005667	transcription factor complex

tr|T1FMJ0|T1FMJ0_HELRO
Uncharacterized protein
Search

RNF41

0.92	E3 ubiquitin protein ligase neuregulin receptor degradation protein-1

0.73	GO:0016567	protein ubiquitination
0.54	GO:1901525	negative regulation of mitophagy
0.53	GO:0097191	extrinsic apoptotic signaling pathway
0.52	GO:2000379	positive regulation of reactive oxygen species metabolic process
0.51	GO:0051896	regulation of protein kinase B signaling
0.51	GO:0030336	negative regulation of cell migration
0.50	GO:0045619	regulation of lymphocyte differentiation
0.50	GO:0045637	regulation of myeloid cell differentiation
0.50	GO:0051091	positive regulation of DNA binding transcription factor activity
0.50	GO:0045732	positive regulation of protein catabolic process

0.76	GO:0061630	ubiquitin protein ligase activity
0.54	GO:0005135	interleukin-3 receptor binding
0.53	GO:0005128	erythropoietin receptor binding
0.53	GO:0046872	metal ion binding
0.53	GO:0017160	Ral GTPase binding
0.52	GO:0030971	receptor tyrosine kinase binding
0.49	GO:0016874	ligase activity
0.48	GO:0019904	protein domain specific binding
0.44	GO:0017022	myosin binding
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity

0.52	GO:0071782	endoplasmic reticulum tubular network
0.49	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0005829	cytosol
0.33	GO:0005634	nucleus

0.49

GO:0016874

tr|T1FMJ1|T1FMJ1_HELRO
Uncharacterized protein
Search

0.52	GO:0055114	oxidation-reduction process
0.36	GO:0006633	fatty acid biosynthetic process

0.54	GO:0016491	oxidoreductase activity
0.39	GO:0004312	fatty acid synthase activity
0.36	GO:0051287	NAD binding

0.30

GO:0044425

membrane part

0.54

GO:0016491

tr|T1FMJ2|T1FMJ2_HELRO
Uncharacterized protein
Search

MPDU1

0.81	Mannose-P-dolichol utilization defect 1

0.45	GO:0009312	oligosaccharide biosynthetic process
0.45	GO:0006488	dolichol-linked oligosaccharide biosynthetic process
0.33	GO:0070588	calcium ion transmembrane transport
0.33	GO:0006457	protein folding
0.33	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.32	GO:0036211	protein modification process
0.32	GO:0044267	cellular protein metabolic process

0.34	GO:0005388	calcium-transporting ATPase activity
0.33	GO:0005515	protein binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0046872	metal ion binding

0.36	GO:0070062	extracellular exosome
0.34	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0042721	mitochondrial inner membrane protein insertion complex
0.33	GO:0005887	integral component of plasma membrane

0.34

EC:3.6.3.8

GO:0005388

tr|T1FMJ3|T1FMJ3_HELRO
Uncharacterized protein
Search

0.10	Putative peptidase m14 carboxypeptidase subfamily protein (Fragment)

0.61	GO:0006508	proteolysis
0.35	GO:0009405	pathogenesis
0.34	GO:0002002	regulation of angiotensin levels in blood
0.34	GO:0006357	regulation of transcription by RNA polymerase II
0.33	GO:0006351	transcription, DNA-templated
0.32	GO:0000272	polysaccharide catabolic process

0.78	GO:0004181	metallocarboxypeptidase activity
0.63	GO:0008270	zinc ion binding
0.34	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.33	GO:0003677	DNA binding
0.32	GO:0004252	serine-type endopeptidase activity

0.39	GO:0005576	extracellular region
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.78

EC:3.4.17

GO:0004181

tr|T1FMJ4|T1FMJ4_HELRO
Transgelin
Search

0.40	Transgelin

0.82	GO:0031032	actomyosin structure organization
0.37	GO:1905515	non-motile cilium assembly

0.73	GO:0003779	actin binding
0.41	GO:0005516	calmodulin binding

0.37

GO:0034464

BBSome

tr|T1FMJ5|T1FMJ5_HELRO
Uncharacterized protein
Search

0.61	GO:0006508	proteolysis
0.52	GO:0042730	fibrinolysis
0.38	GO:2000346	negative regulation of hepatocyte proliferation
0.38	GO:0003331	positive regulation of extracellular matrix constituent secretion
0.38	GO:0010757	negative regulation of plasminogen activation
0.38	GO:0051918	negative regulation of fibrinolysis
0.38	GO:0097421	liver regeneration
0.38	GO:0007596	blood coagulation
0.38	GO:0002002	regulation of angiotensin levels in blood
0.37	GO:0071333	cellular response to glucose stimulus

0.78	GO:0004181	metallocarboxypeptidase activity
0.63	GO:0008270	zinc ion binding
0.34	GO:0005509	calcium ion binding
0.34	GO:0003779	actin binding
0.34	GO:0070003	threonine-type peptidase activity
0.33	GO:0004175	endopeptidase activity
0.33	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.32	GO:0003700	DNA binding transcription factor activity

0.42	GO:0044421	extracellular region part
0.35	GO:0031982	vesicle
0.33	GO:0005839	proteasome core complex
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.78

EC:3.4.17

GO:0004181

tr|T1FMJ6|T1FMJ6_HELRO
Uncharacterized protein
Search

0.41	Synaptic vesicle-associated GTP-binding protein (Fragment)

0.43	GO:0048790	maintenance of presynaptic active zone structure
0.43	GO:0048789	cytoskeletal matrix organization at active zone
0.42	GO:0050804	modulation of chemical synaptic transmission
0.42	GO:0043051	regulation of pharyngeal pumping
0.41	GO:1905488	positive regulation of anterior/posterior axon guidance
0.41	GO:0007271	synaptic transmission, cholinergic
0.41	GO:0007617	mating behavior
0.41	GO:0007419	ventral cord development
0.39	GO:0018125	peptidyl-cysteine methylation
0.39	GO:0051944	positive regulation of catecholamine uptake involved in synaptic transmission

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0031489	myosin V binding
0.38	GO:0030742	GTP-dependent protein binding
0.34	GO:0004767	sphingomyelin phosphodiesterase activity
0.34	GO:0005337	nucleoside transmembrane transporter activity
0.33	GO:0004871	signal transducer activity

0.46	GO:0008021	synaptic vesicle
0.41	GO:0048786	presynaptic active zone
0.38	GO:0043005	neuron projection
0.37	GO:0030141	secretory granule
0.37	GO:0048471	perinuclear region of cytoplasm
0.34	GO:1905360	GTPase complex
0.34	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.34	GO:0030054	cell junction
0.33	GO:0098797	plasma membrane protein complex
0.30	GO:0016021	integral component of membrane

0.34	EC:3.1.4.12	GO:0004767
0.34	KEGG:R02541	GO:0004767

tr|T1FMJ7|T1FMJ7_HELRO
Uncharacterized protein
Search

0.75	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta

0.40	GO:0030590	first cell cycle pseudocleavage
0.40	GO:0010070	zygote asymmetric cell division
0.39	GO:0035046	pronuclear migration
0.39	GO:0009949	polarity specification of anterior/posterior axis
0.39	GO:0045167	asymmetric protein localization involved in cell fate determination
0.39	GO:0040024	dauer larval development
0.39	GO:0010286	heat acclimation
0.38	GO:0051220	cytoplasmic sequestering of protein
0.38	GO:0006611	protein export from nucleus
0.38	GO:0042308	negative regulation of protein import into nucleus

0.77	GO:0019904	protein domain specific binding
0.39	GO:0004497	monooxygenase activity
0.36	GO:0008134	transcription factor binding
0.35	GO:0008426	protein kinase C inhibitor activity
0.34	GO:0042803	protein homodimerization activity
0.34	GO:0046982	protein heterodimerization activity

0.37	GO:0005634	nucleus
0.37	GO:0005938	cell cortex
0.35	GO:0045172	germline ring canal
0.34	GO:0005769	early endosome
0.33	GO:0005829	cytosol
0.33	GO:0031967	organelle envelope
0.33	GO:0031090	organelle membrane
0.32	GO:0005886	plasma membrane

tr|T1FMJ8|T1FMJ8_HELRO
Uncharacterized protein
Search

0.36	Beta-ketoacyl-acyl-carrier-protein synthase II

0.68	GO:0006633	fatty acid biosynthetic process
0.37	GO:0051791	medium-chain fatty acid metabolic process
0.36	GO:0046459	short-chain fatty acid metabolic process
0.35	GO:0006637	acyl-CoA metabolic process

0.63

GO:0016747

transferase activity, transferring acyl groups other than amino-acyl groups

0.35	GO:0005739	mitochondrion
0.35	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.63

GO:0016747

tr|T1FMJ9|T1FMJ9_HELRO
Uncharacterized protein
Search

0.40	Monocarboxylate transporter

0.54	GO:0055085	transmembrane transport
0.36	GO:0015718	monocarboxylic acid transport
0.33	GO:0032392	DNA geometric change
0.31	GO:1901360	organic cyclic compound metabolic process
0.31	GO:0046483	heterocycle metabolic process
0.31	GO:0006725	cellular aromatic compound metabolic process
0.31	GO:0006807	nitrogen compound metabolic process
0.30	GO:0044238	primary metabolic process

0.37	GO:0008028	monocarboxylic acid transmembrane transporter activity
0.33	GO:0004003	ATP-dependent DNA helicase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0003677	DNA binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.32	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|T1FMK0|T1FMK0_HELRO
Uncharacterized protein
Search

GMPS

0.77	Guanine monophosphate synthase

0.77

GO:0006177

GMP biosynthetic process

0.79	GO:0003922	GMP synthase (glutamine-hydrolyzing) activity
0.58	GO:0016462	pyrophosphatase activity
0.56	GO:0003921	GMP synthase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.57

GO:0005829

cytosol

0.79

EC:6.3.5.2

GO:0003922

tr|T1FMK1|T1FMK1_HELRO
Uncharacterized protein
Search

tr|T1FMK2|T1FMK2_HELRO
Uncharacterized protein
Search

0.68	GO:0016192	vesicle-mediated transport
0.65	GO:0006886	intracellular protein transport
0.64	GO:0061025	membrane fusion
0.46	GO:0048284	organelle fusion
0.46	GO:0016050	vesicle organization
0.46	GO:0140056	organelle localization by membrane tethering
0.40	GO:0072666	establishment of protein localization to vacuole
0.39	GO:0007034	vacuolar transport
0.39	GO:0016197	endosomal transport

0.76	GO:0005484	SNAP receptor activity
0.47	GO:0000149	SNARE binding

0.47	GO:0031201	SNARE complex
0.44	GO:0012505	endomembrane system
0.40	GO:0030136	clathrin-coated vesicle
0.39	GO:0005774	vacuolar membrane
0.39	GO:0005798	Golgi-associated vesicle
0.30	GO:0031224	intrinsic component of membrane

tr|T1FMK3|T1FMK3_HELRO
Uncharacterized protein
Search

MSN

0.85	Ezrin-moesin-radixin

0.54	GO:0070489	T cell aggregation
0.52	GO:0022614	membrane to membrane docking
0.52	GO:1902965	regulation of protein localization to early endosome
0.52	GO:0001771	immunological synapse formation
0.52	GO:2000643	positive regulation of early endosome to late endosome transport
0.52	GO:1905668	positive regulation of protein localization to endosome
0.52	GO:0071394	cellular response to testosterone stimulus
0.52	GO:0072678	T cell migration
0.51	GO:0045198	establishment of epithelial cell apical/basal polarity
0.51	GO:0061028	establishment of endothelial barrier

0.72	GO:0003779	actin binding
0.48	GO:0050839	cell adhesion molecule binding
0.47	GO:0019901	protein kinase binding
0.46	GO:0003725	double-stranded RNA binding
0.45	GO:0005102	receptor binding
0.35	GO:0005198	structural molecule activity
0.34	GO:0044548	S100 protein binding
0.34	GO:0034237	protein kinase A regulatory subunit binding
0.34	GO:0097718	disordered domain specific binding
0.34	GO:0051117	ATPase binding

0.69	GO:0005856	cytoskeleton
0.52	GO:0071437	invadopodium
0.51	GO:0031143	pseudopodium
0.51	GO:0005902	microvillus
0.50	GO:0001931	uropod
0.50	GO:0016324	apical plasma membrane
0.50	GO:0030175	filopodium
0.48	GO:0005925	focal adhesion
0.48	GO:0043209	myelin sheath
0.48	GO:0048471	perinuclear region of cytoplasm

tr|T1FMK4|T1FMK4_HELRO
Uncharacterized protein
Search

RPL38

0.79	Ribosomal protein rpl38

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.48	GO:0022618	ribonucleoprotein complex assembly
0.47	GO:0048318	axial mesoderm development
0.47	GO:0009790	embryo development
0.45	GO:0001503	ossification
0.44	GO:0043583	ear development
0.44	GO:0007605	sensory perception of sound

0.64	GO:0003735	structural constituent of ribosome
0.40	GO:0003723	RNA binding
0.33	GO:0008168	methyltransferase activity

0.61	GO:0005840	ribosome
0.49	GO:0033291	eukaryotic 80S initiation complex
0.47	GO:0044445	cytosolic part
0.44	GO:0005844	polysome
0.41	GO:0044446	intracellular organelle part
0.36	GO:0005925	focal adhesion
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0008168

tr|T1FMK5|T1FMK5_HELRO
Uncharacterized protein
Search

0.80	GO:0060079	excitatory postsynaptic potential
0.77	GO:0035235	ionotropic glutamate receptor signaling pathway
0.59	GO:0006811	ion transport
0.48	GO:0055085	transmembrane transport
0.42	GO:0035249	synaptic transmission, glutamatergic
0.42	GO:0007274	neuromuscular synaptic transmission
0.41	GO:0030510	regulation of BMP signaling pathway
0.41	GO:0019722	calcium-mediated signaling

0.82	GO:0005234	extracellularly glutamate-gated ion channel activity
0.77	GO:0004970	ionotropic glutamate receptor activity
0.41	GO:0099604	ligand-gated calcium channel activity

0.78	GO:0098794	postsynapse
0.68	GO:0097060	synaptic membrane
0.64	GO:0030054	cell junction
0.42	GO:0008328	ionotropic glutamate receptor complex
0.41	GO:0031594	neuromuscular junction
0.35	GO:0043226	organelle
0.33	GO:0005622	intracellular

tr|T1FMK6|T1FMK6_HELRO
Uncharacterized protein
Search

0.72	Actin regulatory protein CAP-G

0.47	GO:0051017	actin filament bundle assembly
0.40	GO:0051693	actin filament capping
0.39	GO:0030043	actin filament fragmentation
0.39	GO:0051014	actin filament severing
0.35	GO:0030041	actin filament polymerization
0.35	GO:0045010	actin nucleation
0.34	GO:0007275	multicellular organism development
0.34	GO:2000012	regulation of auxin polar transport
0.34	GO:0009630	gravitropism
0.33	GO:0001558	regulation of cell growth

0.78	GO:0051015	actin filament binding
0.36	GO:0005509	calcium ion binding
0.35	GO:0005544	calcium-dependent phospholipid binding
0.35	GO:0048306	calcium-dependent protein binding
0.34	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity

0.37	GO:0005856	cytoskeleton
0.34	GO:0045335	phagocytic vesicle
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.34	EC:3.2.1.113	GO:0004571
0.34	KEGG:R05982 KEGG:R06722	GO:0004571

tr|T1FMK7|T1FMK7_HELRO
Extended synaptotagmin-like protein 2b
Search

0.59	Extended synaptotagmin-2

0.80	GO:0061817	endoplasmic reticulum-plasma membrane tethering
0.70	GO:0006869	lipid transport
0.39	GO:0016079	synaptic vesicle exocytosis
0.34	GO:0006950	response to stress
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression
0.33	GO:0016310	phosphorylation

0.71	GO:0008289	lipid binding
0.34	GO:0043168	anion binding
0.33	GO:0016301	kinase activity
0.33	GO:0050997	quaternary ammonium group binding
0.32	GO:0070405	ammonium ion binding
0.32	GO:0045296	cadherin binding
0.32	GO:0042802	identical protein binding
0.32	GO:0005509	calcium ion binding

0.39	GO:0008021	synaptic vesicle
0.37	GO:0005887	integral component of plasma membrane
0.36	GO:0005783	endoplasmic reticulum
0.32	GO:0044232	organelle membrane contact site
0.32	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.32	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.32	GO:0031984	organelle subcompartment

tr|T1FMK8|T1FMK8_HELRO
Uncharacterized protein
Search

DNAJC3

0.41	Interferon-induced, double-stranded RNA-activated protein kinase inhibitor (Fragment)

0.78	GO:0036494	positive regulation of translation initiation in response to endoplasmic reticulum stress
0.75	GO:1903912	negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
0.68	GO:0070417	cellular response to cold
0.66	GO:0006469	negative regulation of protein kinase activity
0.63	GO:0043066	negative regulation of apoptotic process
0.59	GO:0051603	proteolysis involved in cellular protein catabolic process
0.45	GO:0016310	phosphorylation
0.43	GO:0006986	response to unfolded protein
0.41	GO:0035967	cellular response to topologically incorrect protein
0.39	GO:0043312	neutrophil degranulation

0.71	GO:0051787	misfolded protein binding
0.68	GO:0004860	protein kinase inhibitor activity
0.65	GO:0019901	protein kinase binding
0.63	GO:0051087	chaperone binding
0.46	GO:0016301	kinase activity
0.35	GO:0016773	phosphotransferase activity, alcohol group as acceptor

0.70	GO:0031205	endoplasmic reticulum Sec complex
0.68	GO:0005788	endoplasmic reticulum lumen
0.58	GO:0005829	cytosol
0.47	GO:0005790	smooth endoplasmic reticulum
0.39	GO:0035578	azurophil granule lumen
0.38	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.35

GO:0016773

tr|T1FMK9|T1FMK9_HELRO
Sorting nexin
Search

SNX5

0.74	Sorting nexin

0.62	GO:0015031	protein transport
0.59	GO:0006907	pinocytosis
0.52	GO:0046907	intracellular transport
0.51	GO:0070727	cellular macromolecule localization
0.44	GO:0016050	vesicle organization
0.36	GO:0061357	positive regulation of Wnt protein secretion
0.34	GO:0030301	cholesterol transport
0.34	GO:0016241	regulation of macroautophagy
0.34	GO:0009972	cytidine deamination

0.77	GO:0035091	phosphatidylinositol binding
0.48	GO:0034452	dynactin binding
0.45	GO:0045296	cadherin binding
0.34	GO:0008565	protein transporter activity
0.34	GO:0004126	cytidine deaminase activity
0.33	GO:0046982	protein heterodimerization activity
0.33	GO:0008270	zinc ion binding

0.49	GO:0070685	macropinocytic cup
0.48	GO:0097422	tubular endosome
0.48	GO:0031313	extrinsic component of endosome membrane
0.46	GO:0031901	early endosome membrane
0.46	GO:0030904	retromer complex
0.45	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.42	GO:0005829	cytosol
0.37	GO:0001891	phagocytic cup
0.37	GO:0001726	ruffle
0.36	GO:0030659	cytoplasmic vesicle membrane

0.34

EC:3.5.4.5

GO:0004126

tr|T1FML0|T1FML0_HELRO
Uncharacterized protein
Search

LZIC

0.94	Leucine zipper and CTNNBIP1 domain containing

0.52	GO:0007417	central nervous system development
0.38	GO:0010212	response to ionizing radiation

0.84

GO:0008013

beta-catenin binding

tr|T1FML1|T1FML1_HELRO
Uncharacterized protein
Search

UBE2N

0.55	Ubiquitin-conjugating enzyme

0.51	GO:0070534	protein K63-linked ubiquitination
0.49	GO:0006301	postreplication repair
0.44	GO:0033182	regulation of histone ubiquitination
0.44	GO:0000729	DNA double-strand break processing
0.44	GO:0045739	positive regulation of DNA repair
0.43	GO:0031058	positive regulation of histone modification
0.43	GO:0050852	T cell receptor signaling pathway
0.43	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.43	GO:0016574	histone ubiquitination
0.43	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling

0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0004842	ubiquitin-protein transferase activity
0.46	GO:0031625	ubiquitin protein ligase binding
0.46	GO:0061659	ubiquitin-like protein ligase activity
0.45	GO:0061650	ubiquitin-like protein conjugating enzyme activity
0.43	GO:0043130	ubiquitin binding
0.38	GO:0016874	ligase activity
0.33	GO:0003723	RNA binding

0.46	GO:0031372	UBC13-MMS2 complex
0.46	GO:0035370	UBC13-UEV1A complex
0.43	GO:0005634	nucleus
0.41	GO:0000151	ubiquitin ligase complex
0.39	GO:0031974	membrane-enclosed lumen
0.37	GO:0043232	intracellular non-membrane-bounded organelle
0.37	GO:0005737	cytoplasm
0.37	GO:0044446	intracellular organelle part
0.36	GO:0070062	extracellular exosome
0.33	GO:0012505	endomembrane system

0.38	EC:6	GO:0016874
0.48	KEGG:R03876	GO:0004842

tr|T1FML2|T1FML2_HELRO
Carboxypeptidase
Search

CTSA

0.56	Carboxypeptidase

0.60	GO:0006508	proteolysis
0.41	GO:0044257	cellular protein catabolic process
0.35	GO:1904715	negative regulation of chaperone-mediated autophagy
0.34	GO:0031647	regulation of protein stability
0.33	GO:0006368	transcription elongation from RNA polymerase II promoter

0.74	GO:0004185	serine-type carboxypeptidase activity
0.33	GO:0005515	protein binding

0.47	GO:0005654	nucleoplasm
0.37	GO:0005765	lysosomal membrane
0.34	GO:0070062	extracellular exosome
0.33	GO:0005739	mitochondrion
0.32	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

0.74

EC:3.4.16

GO:0004185

tr|T1FML3|T1FML3_HELRO
Proteasome subunit alpha type
Search

PSMA4

0.49	Proteasome endopeptidase complex

0.72	GO:0006511	ubiquitin-dependent protein catabolic process
0.35	GO:0010608	posttranscriptional regulation of gene expression
0.35	GO:0032269	negative regulation of cellular protein metabolic process
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0034249	negative regulation of cellular amide metabolic process
0.35	GO:0006879	cellular iron ion homeostasis
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.35	GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway

0.77	GO:0004298	threonine-type endopeptidase activity
0.36	GO:0030350	iron-responsive element binding
0.36	GO:0030371	translation repressor activity
0.33	GO:0004252	serine-type endopeptidase activity
0.33	GO:0005515	protein binding

0.79	GO:0019773	proteasome core complex, alpha-subunit complex
0.61	GO:0005634	nucleus
0.50	GO:0000932	P-body
0.47	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.77

EC:3.4.25

GO:0004298

tr|T1FML4|T1FML4_HELRO
Uncharacterized protein
Search

0.83	BUD23, rRNA methyltransferase and ribosome maturation factor

0.78	GO:0070476	rRNA (guanine-N7)-methylation
0.39	GO:0000056	ribosomal small subunit export from nucleus
0.39	GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.34	GO:0001731	formation of translation preinitiation complex

0.76	GO:0016435	rRNA (guanine) methyltransferase activity
0.33	GO:0003743	translation initiation factor activity

0.44	GO:0005730	nucleolus
0.34	GO:0016282	eukaryotic 43S preinitiation complex
0.34	GO:0033290	eukaryotic 48S preinitiation complex
0.34	GO:0005852	eukaryotic translation initiation factor 3 complex
0.30	GO:0031224	intrinsic component of membrane

0.76

GO:0016435

tr|T1FML5|T1FML5_HELRO
Uncharacterized protein
Search

0.80	Charged multivesicular body protein 1

0.78	GO:0007034	vacuolar transport
0.44	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway
0.38	GO:0045184	establishment of protein localization
0.37	GO:1901673	regulation of mitotic spindle assembly
0.37	GO:0042886	amide transport
0.37	GO:0000920	cell separation after cytokinesis
0.37	GO:0007080	mitotic metaphase plate congression
0.37	GO:0010824	regulation of centrosome duplication
0.36	GO:0006997	nucleus organization
0.36	GO:0071702	organic substance transport

0.36	GO:0019904	protein domain specific binding
0.35	GO:0042802	identical protein binding

0.45	GO:0005770	late endosome
0.42	GO:0045177	apical part of cell
0.40	GO:0010008	endosome membrane
0.37	GO:0005829	cytosol
0.37	GO:0036452	ESCRT complex
0.36	GO:0030496	midbody
0.36	GO:0030117	membrane coat
0.34	GO:0005634	nucleus

tr|T1FML6|T1FML6_HELRO
Uncharacterized protein
Search

0.87	Intermediate filament gliarin

0.50	GO:0031175	neuron projection development
0.38	GO:0010625	positive regulation of Schwann cell proliferation
0.38	GO:1904714	regulation of chaperone-mediated autophagy
0.37	GO:0060020	Bergmann glial cell differentiation
0.37	GO:0045104	intermediate filament cytoskeleton organization
0.37	GO:0051580	regulation of neurotransmitter uptake
0.37	GO:0014002	astrocyte development
0.37	GO:0060291	long-term synaptic potentiation
0.37	GO:0010977	negative regulation of neuron projection development
0.37	GO:0031099	regeneration

0.62	GO:0005198	structural molecule activity
0.35	GO:0042802	identical protein binding
0.33	GO:1990254	keratin filament binding

0.79	GO:0005882	intermediate filament
0.40	GO:0044444	cytoplasmic part
0.38	GO:0097450	astrocyte end-foot
0.36	GO:0043209	myelin sheath
0.36	GO:0044297	cell body
0.33	GO:0016327	apicolateral plasma membrane
0.33	GO:0042383	sarcolemma
0.33	GO:0005885	Arp2/3 protein complex
0.33	GO:0005911	cell-cell junction
0.32	GO:0043231	intracellular membrane-bounded organelle

tr|T1FML7|T1FML7_HELRO
Uncharacterized protein
Search

PCID2

0.95	Novel protein, containing PCI domain

0.82	GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint
0.81	GO:0045579	positive regulation of B cell differentiation
0.80	GO:0048536	spleen development
0.78	GO:2000117	negative regulation of cysteine-type endopeptidase activity
0.77	GO:0043488	regulation of mRNA stability
0.72	GO:0043066	negative regulation of apoptotic process
0.70	GO:0000973	posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery
0.70	GO:0071033	nuclear retention of pre-mRNA at the site of transcription
0.68	GO:0045893	positive regulation of transcription, DNA-templated
0.67	GO:0016973	poly(A)+ mRNA export from nucleus

0.59	GO:0003690	double-stranded DNA binding
0.50	GO:0003723	RNA binding
0.40	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.40	GO:0004725	protein tyrosine phosphatase activity
0.36	GO:0005515	protein binding

0.69	GO:0070390	transcription export complex 2
0.68	GO:0035327	transcriptionally active chromatin
0.62	GO:0005643	nuclear pore
0.36	GO:0005856	cytoskeleton
0.30	GO:0016020	membrane

0.40

EC:3.1.3

GO:0008138

tr|T1FML8|T1FML8_HELRO
Uncharacterized protein
Search

0.60	Actin-binding Rho-activating protein (inferred by orthology to a human protein)

0.84

GO:0035025

positive regulation of Rho protein signal transduction

0.70

GO:0003779

actin binding

0.70	GO:0015629	actin cytoskeleton
0.30	GO:0044425	membrane part

tr|T1FML9|T1FML9_HELRO
Uncharacterized protein
Search

RDH13

0.30	Protochlorophyllide reductase

0.48	GO:0055114	oxidation-reduction process
0.35	GO:0019290	siderophore biosynthetic process
0.34	GO:0032259	methylation

0.49	GO:0016491	oxidoreductase activity
0.37	GO:0008825	cyclopropane-fatty-acyl-phospholipid synthase activity
0.37	GO:0004312	fatty acid synthase activity
0.33	GO:0016787	hydrolase activity

0.30

GO:0044425

membrane part

0.49

GO:0016491

tr|T1FMM0|T1FMM0_HELRO
Uncharacterized protein
Search

0.71	Allergen tropomyosin

0.77	GO:0006936	muscle contraction
0.70	GO:0007015	actin filament organization
0.66	GO:0034609	spicule insertion
0.57	GO:0043393	regulation of protein binding
0.56	GO:0030835	negative regulation of actin filament depolymerization
0.55	GO:0009792	embryo development ending in birth or egg hatching
0.54	GO:0030833	regulation of actin filament polymerization
0.49	GO:0040011	locomotion
0.46	GO:0006260	DNA replication
0.43	GO:0006351	transcription, DNA-templated

0.82	GO:0008307	structural constituent of muscle
0.73	GO:0051015	actin filament binding
0.44	GO:0003700	DNA binding transcription factor activity
0.41	GO:0003677	DNA binding

0.85	GO:0005862	muscle thin filament tropomyosin
0.77	GO:0005884	actin filament
0.44	GO:0005634	nucleus

tr|T1FMM1|T1FMM1_HELRO
Ribonucleoside-diphosphate reductase
Search

RRM1

0.56	Ribonucleoside-diphosphate reductase large subunit

0.66	GO:0006260	DNA replication
0.53	GO:0051290	protein heterotetramerization
0.53	GO:0055114	oxidation-reduction process
0.48	GO:0009263	deoxyribonucleotide biosynthetic process
0.36	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.36	GO:0042246	tissue regeneration
0.35	GO:0021846	cell proliferation in forebrain
0.35	GO:0015949	nucleobase-containing small molecule interconversion
0.35	GO:0008584	male gonad development
0.35	GO:0060041	retina development in camera-type eye

0.77	GO:0061731	ribonucleoside-diphosphate reductase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0097718	disordered domain specific binding
0.48	GO:0042802	identical protein binding
0.34	GO:0016992	lipoate synthase activity
0.33	GO:0051539	4 iron, 4 sulfur cluster binding
0.32	GO:0046872	metal ion binding

0.51	GO:0005971	ribonucleoside-diphosphate reductase complex
0.34	GO:0043025	neuronal cell body
0.34	GO:0070062	extracellular exosome
0.34	GO:0005635	nuclear envelope
0.33	GO:0042995	cell projection
0.33	GO:0005739	mitochondrion

0.34

EC:2.8.1.8

GO:0016992

tr|T1FMM2|T1FMM2_HELRO
Uncharacterized protein
Search

ISOC2

0.86	Isochorismatase domain-containing protein 2

0.48	GO:0031648	protein destabilization
0.34	GO:0071526	semaphorin-plexin signaling pathway
0.33	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.33	GO:0006231	dTMP biosynthetic process
0.33	GO:0000027	ribosomal large subunit assembly
0.32	GO:0032259	methylation
0.32	GO:2001141	regulation of RNA biosynthetic process
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.36	GO:0016787	hydrolase activity
0.34	GO:0017154	semaphorin receptor activity
0.34	GO:0008312	7S RNA binding
0.34	GO:0004799	thymidylate synthase activity
0.33	GO:0043565	sequence-specific DNA binding
0.33	GO:0005515	protein binding
0.33	GO:0003700	DNA binding transcription factor activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding

0.41	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016020	membrane

0.36	EC:3	GO:0016787
0.34	KEGG:R02101	GO:0004799

tr|T1FMM3|T1FMM3_HELRO
Uncharacterized protein
Search

0.51	GO:0016310	phosphorylation
0.40	GO:0017148	negative regulation of translation
0.39	GO:0006879	cellular iron ion homeostasis
0.39	GO:1901565	organonitrogen compound catabolic process
0.38	GO:0044248	cellular catabolic process
0.37	GO:0009057	macromolecule catabolic process
0.36	GO:0006508	proteolysis
0.36	GO:0006553	lysine metabolic process
0.36	GO:0044267	cellular protein metabolic process
0.35	GO:0044282	small molecule catabolic process

0.53	GO:0016301	kinase activity
0.43	GO:0030350	iron-responsive element binding
0.42	GO:0030371	translation repressor activity
0.41	GO:0008483	transaminase activity
0.41	GO:0030170	pyridoxal phosphate binding
0.40	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.39	GO:0070003	threonine-type peptidase activity
0.37	GO:0004175	endopeptidase activity
0.37	GO:0047432	2,2-dialkylglycine decarboxylase (pyruvate) activity
0.34	GO:0005515	protein binding

0.40	GO:0019773	proteasome core complex, alpha-subunit complex
0.37	GO:0005737	cytoplasm
0.35	GO:0031974	membrane-enclosed lumen
0.35	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0044446	intracellular organelle part

0.41	EC:2.6.1	GO:0008483
0.37	KEGG:R03854	GO:0047432

tr|T1FMM4|T1FMM4_HELRO
Uncharacterized protein
Search

0.53	Vacuolar proton-ATPase E-subunit

0.76	GO:0015991	ATP hydrolysis coupled proton transport
0.46	GO:0007430	terminal branching, open tracheal system
0.45	GO:0045176	apical protein localization
0.37	GO:0035556	intracellular signal transduction
0.35	GO:0035002	liquid clearance, open tracheal system
0.35	GO:0032790	ribosome disassembly
0.34	GO:0032447	protein urmylation
0.34	GO:0032543	mitochondrial translation
0.34	GO:0007229	integrin-mediated signaling pathway
0.34	GO:0034227	tRNA thio-modification

0.81	GO:0046961	proton-transporting ATPase activity, rotational mechanism
0.35	GO:0046872	metal ion binding
0.34	GO:0008553	proton-exporting ATPase activity, phosphorylative mechanism
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.72	GO:0033178	proton-transporting two-sector ATPase complex, catalytic domain
0.46	GO:0033181	plasma membrane proton-transporting V-type ATPase complex
0.37	GO:0016324	apical plasma membrane
0.34	GO:0005622	intracellular
0.34	GO:0097223	sperm part
0.34	GO:0008305	integrin complex
0.34	GO:0043227	membrane-bounded organelle
0.33	GO:0098805	whole membrane
0.33	GO:0012505	endomembrane system
0.32	GO:0044422	organelle part

0.34

EC:3.6.3.6

GO:0008553

tr|T1FMM5|T1FMM5_HELRO
Uncharacterized protein
Search

0.66	Troponin T, fast skeletal muscle

0.82	GO:0006937	regulation of muscle contraction
0.34	GO:0050832	defense response to fungus
0.33	GO:0007018	microtubule-based movement
0.33	GO:0030240	skeletal muscle thin filament assembly
0.33	GO:0031640	killing of cells of other organism
0.33	GO:0042742	defense response to bacterium
0.33	GO:0046716	muscle cell cellular homeostasis
0.33	GO:0045214	sarcomere organization
0.33	GO:0048644	muscle organ morphogenesis
0.33	GO:0007498	mesoderm development

0.33	GO:0003777	microtubule motor activity
0.33	GO:0004197	cysteine-type endopeptidase activity
0.33	GO:0016887	ATPase activity
0.32	GO:0003743	translation initiation factor activity
0.32	GO:0032553	ribonucleotide binding
0.32	GO:0017076	purine nucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0005509	calcium ion binding
0.32	GO:0003924	GTPase activity
0.32	GO:0032550	purine ribonucleoside binding

0.83	GO:0005861	troponin complex
0.34	GO:0030286	dynein complex
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:3.4.22

GO:0004197

tr|T1FMM6|T1FMM6_HELRO
Probable ribosome biogenesis protein HELRODRAFT_185298
Search

TSR3

0.72	Ribosome biogenesis protein TSR3

0.66	GO:0006364	rRNA processing
0.42	GO:0042274	ribosomal small subunit biogenesis
0.38	GO:0006415	translational termination
0.35	GO:0006695	cholesterol biosynthetic process
0.34	GO:0007076	mitotic chromosome condensation
0.33	GO:0015074	DNA integration
0.33	GO:0016310	phosphorylation
0.33	GO:0032259	methylation
0.32	GO:0006464	cellular protein modification process
0.32	GO:1903506	regulation of nucleic acid-templated transcription

0.38	GO:0003747	translation release factor activity
0.35	GO:0004631	phosphomevalonate kinase activity
0.33	GO:0004674	protein serine/threonine kinase activity
0.33	GO:0003700	DNA binding transcription factor activity
0.33	GO:0008168	methyltransferase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.41	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.35	EC:2.7.4.2	GO:0004631
0.35	KEGG:R03245	GO:0004631

tr|T1FMM7|T1FMM7_HELRO
Uncharacterized protein
Search

ALG3

0.75	Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase

0.70	GO:0097502	mannosylation
0.66	GO:0043413	macromolecule glycosylation
0.66	GO:0009101	glycoprotein biosynthetic process
0.55	GO:0006464	cellular protein modification process
0.35	GO:0006490	oligosaccharide-lipid intermediate biosynthetic process

0.78	GO:0052925	dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity
0.33	GO:0005515	protein binding

0.70	GO:0005783	endoplasmic reticulum
0.64	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.61	GO:0031984	organelle subcompartment
0.30	GO:0044425	membrane part

0.78	EC:2.4.1.258	GO:0052925
0.78	KEGG:R06258	GO:0052925

tr|T1FMM8|T1FMM8_HELRO
Uncharacterized protein
Search

PDE6D

0.84	cGMP phosphodiesterase delta subunit

0.73	GO:0007601	visual perception
0.49	GO:0034260	negative regulation of GTPase activity
0.43	GO:0001822	kidney development
0.42	GO:0001654	eye development
0.35	GO:0050896	response to stimulus
0.33	GO:0023052	signaling
0.33	GO:0007154	cell communication
0.33	GO:0050794	regulation of cellular process

0.74	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.50	GO:0005095	GTPase inhibitor activity
0.47	GO:0017137	Rab GTPase binding
0.33	GO:0004930	G-protein coupled receptor activity
0.33	GO:0005509	calcium ion binding

0.44	GO:0031410	cytoplasmic vesicle
0.43	GO:0005829	cytosol
0.37	GO:0012506	vesicle membrane
0.36	GO:0005856	cytoskeleton
0.36	GO:0042995	cell projection
0.34	GO:0044446	intracellular organelle part
0.34	GO:0098590	plasma membrane region
0.34	GO:0097458	neuron part
0.33	GO:0098588	bounding membrane of organelle
0.30	GO:0031224	intrinsic component of membrane

0.74

EC:3.1.4.17

GO:0004114

tr|T1FMM9|T1FMM9_HELRO
Delta-aminolevulinic acid dehydratase
Search

ALAD

0.49	Delta-aminolevulinic acid dehydratase

0.69	GO:0006779	porphyrin-containing compound biosynthetic process
0.50	GO:0071353	cellular response to interleukin-4
0.49	GO:1901799	negative regulation of proteasomal protein catabolic process
0.48	GO:0042168	heme metabolic process
0.47	GO:0046148	pigment biosynthetic process
0.46	GO:0051260	protein homooligomerization
0.38	GO:0070541	response to platinum ion
0.38	GO:0071284	cellular response to lead ion
0.37	GO:0010266	response to vitamin B1
0.37	GO:0033197	response to vitamin E

0.79	GO:0004655	porphobilinogen synthase activity
0.53	GO:0046872	metal ion binding
0.45	GO:0042802	identical protein binding
0.38	GO:1904854	proteasome core complex binding

0.40	GO:0005829	cytosol
0.35	GO:0005839	proteasome core complex
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0005615	extracellular space
0.35	GO:0034774	secretory granule lumen
0.34	GO:1903561	extracellular vesicle
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.79	EC:4.2.1.24	GO:0004655
0.79	KEGG:R00036	GO:0004655

tr|T1FMN0|T1FMN0_HELRO
Uncharacterized protein
Search

0.59	Putative cytochrome b5 outer mitochondrial membrane variant 1

0.35	GO:0055114	oxidation-reduction process
0.34	GO:0046686	response to cadmium ion
0.34	GO:0072663	establishment of protein localization to peroxisome
0.34	GO:0043574	peroxisomal transport
0.34	GO:0043085	positive regulation of catalytic activity
0.33	GO:0006366	transcription by RNA polymerase II
0.33	GO:0006605	protein targeting
0.33	GO:0006508	proteolysis
0.32	GO:0006355	regulation of transcription, DNA-templated

0.62	GO:0020037	heme binding
0.53	GO:0046872	metal ion binding
0.40	GO:0019899	enzyme binding
0.35	GO:0009703	nitrate reductase (NADH) activity
0.34	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.34	GO:0008047	enzyme activator activity
0.33	GO:0004252	serine-type endopeptidase activity
0.33	GO:0042623	ATPase activity, coupled
0.32	GO:0003700	DNA binding transcription factor activity
0.32	GO:0030554	adenyl nucleotide binding

0.40	GO:0005829	cytosol
0.39	GO:0005739	mitochondrion
0.37	GO:0031090	organelle membrane
0.37	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0031967	organelle envelope
0.35	GO:0098805	whole membrane
0.34	GO:0044438	microbody part
0.34	GO:0005777	peroxisome
0.33	GO:0019867	outer membrane
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:1.7.1.1

GO:0009703

tr|T1FMN1|T1FMN1_HELRO
Uncharacterized protein
Search

0.53	GO:0007160	cell-matrix adhesion
0.44	GO:0006897	endocytosis
0.40	GO:0007275	multicellular organism development
0.40	GO:0007219	Notch signaling pathway
0.40	GO:0030154	cell differentiation
0.39	GO:0060322	head development
0.39	GO:0050793	regulation of developmental process
0.38	GO:0071397	cellular response to cholesterol
0.38	GO:0051239	regulation of multicellular organismal process
0.38	GO:0038026	reelin-mediated signaling pathway

0.66	GO:0005509	calcium ion binding
0.49	GO:0030229	very-low-density lipoprotein particle receptor activity
0.38	GO:0038025	reelin receptor activity
0.38	GO:0008035	high-density lipoprotein particle binding
0.38	GO:0005041	low-density lipoprotein receptor activity
0.38	GO:0034185	apolipoprotein binding
0.37	GO:0019894	kinesin binding
0.36	GO:0048306	calcium-dependent protein binding
0.35	GO:0017147	Wnt-protein binding
0.35	GO:0042813	Wnt-activated receptor activity

0.47	GO:0005901	caveola
0.45	GO:0043235	receptor complex
0.37	GO:0014069	postsynaptic density
0.37	GO:0030425	dendrite
0.37	GO:0030424	axon
0.37	GO:0043025	neuronal cell body
0.36	GO:0005875	microtubule associated complex
0.36	GO:0005576	extracellular region
0.34	GO:0016324	apical plasma membrane
0.34	GO:0030139	endocytic vesicle

tr|T1FMN2|T1FMN2_HELRO
Uncharacterized protein
Search

0.47	L-threonine dehydratase catabolic TdcB

0.71

GO:0006567

threonine catabolic process

0.72	GO:0004794	L-threonine ammonia-lyase activity
0.37	GO:0030170	pyridoxal phosphate binding

0.30

GO:0031224

intrinsic component of membrane

0.72

EC:4.3.1.19

GO:0004794

tr|T1FMN3|T1FMN3_HELRO
Uncharacterized protein
Search

LGMN

0.91	Asparaginyl endopeptidase

0.61	GO:0006508	proteolysis
0.50	GO:0040015	negative regulation of multicellular organism growth
0.49	GO:1901185	negative regulation of ERBB signaling pathway
0.49	GO:0010447	response to acidic pH
0.49	GO:0043524	negative regulation of neuron apoptotic process
0.49	GO:0003014	renal system process
0.47	GO:0032801	receptor catabolic process
0.46	GO:0044257	cellular protein catabolic process
0.45	GO:0031103	axon regeneration
0.44	GO:0042246	tissue regeneration

0.61	GO:0008233	peptidase activity
0.33	GO:0022857	transmembrane transporter activity
0.33	GO:0015002	heme-copper terminal oxidase activity
0.33	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.33	GO:0043492	ATPase activity, coupled to movement of substances
0.33	GO:0009055	electron transfer activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.47	GO:0005770	late endosome
0.47	GO:0045177	apical part of cell
0.47	GO:0005773	vacuole
0.34	GO:0070062	extracellular exosome
0.33	GO:0031966	mitochondrial membrane
0.33	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.61

GO:0008233

tr|T1FMN4|T1FMN4_HELRO
Uncharacterized protein
Search

0.10

Cullin-4

0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.48	GO:0035518	histone H2A monoubiquitination
0.48	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle
0.47	GO:0070914	UV-damage excision repair
0.46	GO:0045732	positive regulation of protein catabolic process
0.44	GO:0010498	proteasomal protein catabolic process
0.39	GO:0035118	embryonic pectoral fin morphogenesis
0.39	GO:0071600	otic vesicle morphogenesis
0.37	GO:0007507	heart development
0.35	GO:0031175	neuron projection development

0.79	GO:0031625	ubiquitin protein ligase binding
0.43	GO:0003684	damaged DNA binding
0.42	GO:0061630	ubiquitin protein ligase activity
0.33	GO:0016874	ligase activity
0.32	GO:0008168	methyltransferase activity

0.76	GO:0031461	cullin-RING ubiquitin ligase complex
0.43	GO:0005654	nucleoplasm
0.42	GO:0005829	cytosol
0.34	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.33

GO:0016874

tr|T1FMN5|T1FMN5_HELRO
Uncharacterized protein
Search

CCZ1

0.89	CCZ1 vacuolar protein trafficking and biogenesis associated homolog

0.65	GO:0016192	vesicle-mediated transport
0.54	GO:0007041	lysosomal transport
0.51	GO:0016197	endosomal transport
0.43	GO:0065009	regulation of molecular function
0.43	GO:0090382	phagosome maturation
0.42	GO:0007040	lysosome organization
0.41	GO:0016050	vesicle organization
0.39	GO:0070925	organelle assembly
0.39	GO:0098657	import into cell
0.37	GO:0006914	autophagy

0.46	GO:0005085	guanyl-nucleotide exchange factor activity
0.42	GO:0005509	calcium ion binding
0.37	GO:0017137	Rab GTPase binding

0.65	GO:0031982	vesicle
0.53	GO:0005765	lysosomal membrane
0.49	GO:0005829	cytosol
0.45	GO:0016235	aggresome
0.43	GO:0012505	endomembrane system
0.40	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

tr|T1FMN6|T1FMN6_HELRO
Uncharacterized protein
Search

ABHD16A

0.59	Abhydrolase domain-containing protein 16A

0.51	GO:1905344	prostaglandin catabolic process
0.51	GO:0052651	monoacylglycerol catabolic process

0.48	GO:0047372	acylglycerol lipase activity
0.36	GO:0004622	lysophospholipase activity
0.33	GO:0005515	protein binding

0.33	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

0.48

EC:3.1.1.23

GO:0047372

tr|T1FMN7|T1FMN7_HELRO
Uncharacterized protein
Search

ACAD9

0.84	Very-long-chain specific acyl-CoA dehydrogenase, mitochondrial protein

0.53

GO:0055114

oxidation-reduction process

0.74	GO:0003995	acyl-CoA dehydrogenase activity
0.66	GO:0050660	flavin adenine dinucleotide binding

0.74

EC:1.3.99.3

GO:0003995

tr|T1FMN8|T1FMN8_HELRO
Uncharacterized protein
Search

COPS6

0.80	COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis)

0.84	GO:0000338	protein deneddylation
0.46	GO:0048140	male germ-line cyst encapsulation
0.45	GO:0036099	female germ-line stem cell population maintenance
0.42	GO:0050821	protein stabilization
0.42	GO:0007281	germ cell development
0.34	GO:0007292	female gamete generation
0.33	GO:0006413	translational initiation
0.33	GO:0007275	multicellular organism development

0.41	GO:0042802	identical protein binding
0.40	GO:0046983	protein dimerization activity
0.34	GO:0008270	zinc ion binding
0.33	GO:0003743	translation initiation factor activity
0.33	GO:0008237	metallopeptidase activity

0.81	GO:0008180	COP9 signalosome
0.35	GO:0005654	nucleoplasm
0.34	GO:1905369	endopeptidase complex
0.33	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1FMN9|T1FMN9_HELRO
Uncharacterized protein
Search

LENG1

0.96	Leukocyte receptor cluster member 1

0.37

GO:0006508

proteolysis

0.44	GO:0005515	protein binding
0.41	GO:0004181	metallocarboxypeptidase activity
0.38	GO:0008270	zinc ion binding
0.36	GO:0003677	DNA binding

0.41	GO:0005730	nucleolus
0.30	GO:0044425	membrane part

0.41

EC:3.4.17

GO:0004181

tr|T1FMP0|T1FMP0_HELRO
Uncharacterized protein
Search

tr|T1FMP1|T1FMP1_HELRO
Fructose-bisphosphate aldolase
Search

0.55	Fructose-bisphosphate aldolase class-I

0.70	GO:0006757	ATP generation from ADP
0.69	GO:0006090	pyruvate metabolic process
0.68	GO:0016052	carbohydrate catabolic process
0.67	GO:0019362	pyridine nucleotide metabolic process
0.37	GO:0009888	tissue development
0.37	GO:0030388	fructose 1,6-bisphosphate metabolic process
0.37	GO:0001966	thigmotaxis
0.36	GO:0030154	cell differentiation
0.36	GO:0043473	pigmentation
0.36	GO:0035282	segmentation

0.79	GO:0004332	fructose-bisphosphate aldolase activity
0.35	GO:0008092	cytoskeletal protein binding
0.35	GO:0070061	fructose binding
0.34	GO:0045296	cadherin binding

0.35	GO:0061827	sperm head
0.34	GO:0031430	M band
0.34	GO:0005829	cytosol
0.34	GO:0030018	Z disc
0.34	GO:0070062	extracellular exosome
0.33	GO:0015629	actin cytoskeleton
0.33	GO:0005739	mitochondrion

0.79

EC:4.1.2.13

GO:0004332

tr|T1FMP2|T1FMP2_HELRO
Uncharacterized protein
Search

DCAF7

0.94	WD repeat-containing protein 68

0.55	GO:0048703	embryonic viscerocranium morphogenesis
0.54	GO:0051216	cartilage development
0.51	GO:0048627	myoblast development
0.50	GO:0035332	positive regulation of hippo signaling
0.48	GO:0048747	muscle fiber development
0.47	GO:0045927	positive regulation of growth
0.47	GO:0007517	muscle organ development
0.39	GO:0019538	protein metabolic process
0.38	GO:0043412	macromolecule modification
0.36	GO:0006325	chromatin organization

0.40	GO:0008241	peptidyl-dipeptidase activity
0.39	GO:0008237	metallopeptidase activity
0.38	GO:0004180	carboxypeptidase activity
0.38	GO:0005515	protein binding
0.38	GO:0004046	aminoacylase activity
0.37	GO:0004402	histone acetyltransferase activity
0.35	GO:0005249	voltage-gated potassium channel activity
0.35	GO:0016875	ligase activity, forming carbon-oxygen bonds
0.35	GO:0140101	catalytic activity, acting on a tRNA
0.35	GO:0030554	adenyl nucleotide binding

0.69	GO:0016363	nuclear matrix
0.69	GO:0080008	Cul4-RING E3 ubiquitin ligase complex
0.65	GO:0016604	nuclear body
0.58	GO:0005829	cytosol
0.51	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.40

EC:3.4.15

GO:0008241

tr|T1FMP3|T1FMP3_HELRO
Peptidyl-prolyl cis-trans isomerase
Search

0.49	Peptidyl-prolyl cis-trans isomerase B

0.72	GO:0000413	protein peptidyl-prolyl isomerization
0.69	GO:0006457	protein folding
0.36	GO:0050821	protein stabilization
0.36	GO:0070681	glutaminyl-tRNAGln biosynthesis via transamidation
0.35	GO:0032543	mitochondrial translation
0.35	GO:0044829	positive regulation by host of viral genome replication
0.35	GO:0040018	positive regulation of multicellular organism growth
0.34	GO:0060348	bone development

0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.44	GO:0016018	cyclosporin A binding
0.35	GO:0032403	protein complex binding
0.35	GO:0050567	glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
0.34	GO:0070063	RNA polymerase binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0016740	transferase activity

0.37	GO:0005615	extracellular space
0.35	GO:0030956	glutamyl-tRNA(Gln) amidotransferase complex
0.35	GO:0034663	endoplasmic reticulum chaperone complex
0.35	GO:0031982	vesicle
0.34	GO:0005788	endoplasmic reticulum lumen
0.34	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0043230	extracellular organelle
0.33	GO:0005739	mitochondrion
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.72

GO:0003755

tr|T1FMP4|T1FMP4_HELRO
Uncharacterized protein
Search

0.52

Flotillin

0.65	GO:0061357	positive regulation of Wnt protein secretion
0.64	GO:0035011	melanotic encapsulation of foreign target
0.63	GO:0007155	cell adhesion

0.48

GO:0005198

structural molecule activity

0.64	GO:0016600	flotillin complex
0.58	GO:0030139	endocytic vesicle
0.55	GO:0005768	endosome
0.52	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

tr|T1FMP5|T1FMP5_HELRO
Uncharacterized protein
Search

HMGCS1

0.67	3-hydroxy-3-methylglutaryl coenzyme A synthase

0.79	GO:0016126	sterol biosynthetic process
0.71	GO:0008299	isoprenoid biosynthetic process
0.44	GO:0014003	oligodendrocyte development
0.34	GO:0033197	response to vitamin E
0.34	GO:0071372	cellular response to follicle-stimulating hormone stimulus
0.34	GO:0071397	cellular response to cholesterol
0.34	GO:0009645	response to low light intensity stimulus
0.34	GO:0071404	cellular response to low-density lipoprotein particle stimulus
0.34	GO:0046690	response to tellurium ion
0.34	GO:0008584	male gonad development

0.83	GO:0004421	hydroxymethylglutaryl-CoA synthase activity
0.34	GO:0008009	chemokine activity
0.33	GO:0042803	protein homodimerization activity
0.33	GO:0043177	organic acid binding
0.32	GO:0016853	isomerase activity
0.32	GO:0008144	drug binding

0.43	GO:0005739	mitochondrion
0.43	GO:0019866	organelle inner membrane
0.33	GO:0005829	cytosol
0.33	GO:0005576	extracellular region

0.83	EC:2.3.3.10	GO:0004421
0.83	KEGG:R01978	GO:0004421

tr|T1FMP6|T1FMP6_HELRO
Uncharacterized protein
Search

PRPF31

0.88	Pre-mRNA processing factor 31

0.85	GO:0000244	spliceosomal tri-snRNP complex assembly
0.48	GO:0071166	ribonucleoprotein complex localization
0.43	GO:0060041	retina development in camera-type eye
0.37	GO:0048254	snoRNA localization
0.33	GO:0006468	protein phosphorylation

0.53	GO:0030622	U4atac snRNA binding
0.52	GO:0070990	snRNP binding
0.52	GO:0030621	U4 snRNA binding
0.33	GO:0004672	protein kinase activity
0.33	GO:0005515	protein binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.81	GO:0046540	U4/U6 x U5 tri-snRNP complex
0.55	GO:0019013	viral nucleocapsid
0.53	GO:0005687	U4 snRNP
0.50	GO:0015030	Cajal body
0.50	GO:0071339	MLL1 complex
0.49	GO:0005690	U4atac snRNP
0.48	GO:0016607	nuclear speck
0.46	GO:0071011	precatalytic spliceosome
0.34	GO:0005684	U2-type spliceosomal complex
0.30	GO:0031224	intrinsic component of membrane

tr|T1FMP7|T1FMP7_HELRO
Uncharacterized protein
Search

CACYBP

0.89	Calcyclin-binding protein (inferred by orthology to a human protein)

0.42	GO:1990823	response to leukemia inhibitory factor
0.40	GO:0071345	cellular response to cytokine stimulus

0.85	GO:0044548	S100 protein binding
0.78	GO:0031625	ubiquitin protein ligase binding
0.72	GO:0015631	tubulin binding
0.40	GO:0042803	protein homodimerization activity
0.40	GO:0019904	protein domain specific binding
0.32	GO:0016874	ligase activity
0.31	GO:0003677	DNA binding

0.43	GO:0030877	beta-catenin destruction complex
0.42	GO:0005641	nuclear envelope lumen
0.41	GO:0019005	SCF ubiquitin ligase complex
0.39	GO:0005654	nucleoplasm
0.39	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016874

tr|T1FMP8|T1FMP8_HELRO
Uncharacterized protein
Search

0.44	Reactive oxygen species modulator

0.51	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.51	GO:2000379	positive regulation of reactive oxygen species metabolic process
0.51	GO:0001302	replicative cell aging
0.50	GO:0050830	defense response to Gram-positive bacterium
0.50	GO:0050829	defense response to Gram-negative bacterium
0.49	GO:0051715	cytolysis in other organism
0.48	GO:0008284	positive regulation of cell proliferation
0.47	GO:0034614	cellular response to reactive oxygen species
0.44	GO:1903146	regulation of autophagy of mitochondrion
0.32	GO:0006508	proteolysis

0.32	GO:0017171	serine hydrolase activity
0.32	GO:0070011	peptidase activity, acting on L-amino acid peptides

0.42	GO:0005739	mitochondrion
0.35	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

tr|T1FMP9|T1FMP9_HELRO
Uncharacterized protein
Search

tr|T1FMQ0|T1FMQ0_HELRO
Uncharacterized protein
Search

0.55	GO:0055085	transmembrane transport
0.41	GO:0006833	water transport
0.40	GO:0003014	renal system process
0.39	GO:0015840	urea transport
0.37	GO:0030437	ascospore formation
0.37	GO:0050891	multicellular organismal water homeostasis
0.36	GO:0071346	cellular response to interferon-gamma

0.69	GO:0022803	passive transmembrane transporter activity
0.41	GO:0005372	water transmembrane transporter activity
0.39	GO:0015204	urea transmembrane transporter activity

0.37	GO:0042807	central vacuole
0.36	GO:0009705	plant-type vacuole membrane
0.36	GO:0009897	external side of plasma membrane
0.34	GO:0031410	cytoplasmic vesicle
0.30	GO:0016021	integral component of membrane

tr|T1FMQ1|T1FMQ1_HELRO
Uncharacterized protein
Search

0.55	GO:0055085	transmembrane transport
0.43	GO:0003014	renal system process
0.42	GO:0006833	water transport
0.39	GO:0015840	urea transport
0.37	GO:0030437	ascospore formation
0.36	GO:0050891	multicellular organismal water homeostasis
0.36	GO:0071346	cellular response to interferon-gamma
0.33	GO:0006811	ion transport

0.69	GO:0022803	passive transmembrane transporter activity
0.42	GO:0005372	water transmembrane transporter activity
0.39	GO:0015204	urea transmembrane transporter activity

0.37	GO:0042807	central vacuole
0.36	GO:0009705	plant-type vacuole membrane
0.36	GO:0009897	external side of plasma membrane
0.34	GO:0031410	cytoplasmic vesicle
0.34	GO:0005887	integral component of plasma membrane

tr|T1FMQ2|T1FMQ2_HELRO
Uncharacterized protein
Search

PDCD6IP

0.81	programmed cell death 6-interacting protein isoform X2

0.65	GO:0000281	mitotic cytokinesis
0.62	GO:0048133	male germ-line stem cell asymmetric division
0.62	GO:1990182	exosomal secretion
0.61	GO:0048132	female germ-line stem cell asymmetric division
0.58	GO:0046330	positive regulation of JNK cascade
0.57	GO:0030041	actin filament polymerization
0.56	GO:1903553	positive regulation of extracellular exosome assembly
0.55	GO:0090611	ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway
0.54	GO:1903543	positive regulation of exosomal secretion
0.53	GO:0000920	cell separation after cytokinesis

0.56	GO:0031871	proteinase activated receptor binding
0.53	GO:0048306	calcium-dependent protein binding
0.52	GO:0005112	Notch binding
0.51	GO:0008022	protein C-terminus binding
0.48	GO:0042803	protein homodimerization activity
0.41	GO:0022857	transmembrane transporter activity
0.38	GO:0046982	protein heterodimerization activity
0.37	GO:0004386	helicase activity
0.37	GO:0003676	nucleic acid binding
0.35	GO:0030554	adenyl nucleotide binding

0.66	GO:0030496	midbody
0.58	GO:0045171	intercellular bridge
0.58	GO:0070938	contractile ring
0.56	GO:0044430	cytoskeletal part
0.55	GO:0031982	vesicle
0.53	GO:0070971	endoplasmic reticulum exit site
0.53	GO:0001772	immunological synapse
0.53	GO:0043230	extracellular organelle
0.52	GO:0015630	microtubule cytoskeleton
0.51	GO:0016323	basolateral plasma membrane

tr|T1FMQ3|T1FMQ3_HELRO
Tetraspanin
Search

0.37	Tetraspanin

0.45	GO:0035188	hatching
0.40	GO:0007166	cell surface receptor signaling pathway
0.35	GO:0045807	positive regulation of endocytosis
0.35	GO:0016477	cell migration
0.34	GO:0007155	cell adhesion
0.34	GO:0006468	protein phosphorylation

0.34	GO:0004672	protein kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.39	GO:0005887	integral component of plasma membrane
0.34	GO:0012505	endomembrane system

tr|T1FMQ4|T1FMQ4_HELRO
Uncharacterized protein
Search

MCAT

0.41	Malonyl-CoA-acyl carrier protein transacylase

0.49	GO:0042967	acyl-carrier-protein biosynthetic process
0.44	GO:0006633	fatty acid biosynthetic process
0.35	GO:0032447	protein urmylation
0.34	GO:0034227	tRNA thio-modification
0.34	GO:0002098	tRNA wobble uridine modification
0.32	GO:0005975	carbohydrate metabolic process
0.31	GO:0055114	oxidation-reduction process

0.64	GO:0004314	[acyl-carrier-protein] S-malonyltransferase activity
0.33	GO:0000049	tRNA binding
0.33	GO:0016772	transferase activity, transferring phosphorus-containing groups
0.33	GO:0047879	erythronolide synthase activity
0.32	GO:0031177	phosphopantetheine binding
0.32	GO:0008483	transaminase activity
0.32	GO:0070279	vitamin B6 binding
0.32	GO:0016874	ligase activity
0.31	GO:0050662	coenzyme binding
0.31	GO:0016788	hydrolase activity, acting on ester bonds

0.40	GO:0005739	mitochondrion
0.32	GO:0005835	fatty acid synthase complex
0.30	GO:0016020	membrane

0.64

EC:2.3.1.39

GO:0004314

tr|T1FMQ5|T1FMQ5_HELRO
Uncharacterized protein
Search

SAR1A

0.77	GTP-binding protein SAR1 (inferred by orthology to a C. elegans protein)

0.69	GO:0006886	intracellular protein transport
0.68	GO:0016192	vesicle-mediated transport
0.44	GO:0051668	localization within membrane
0.44	GO:0016050	vesicle organization
0.41	GO:0061024	membrane organization
0.40	GO:0034622	cellular macromolecular complex assembly
0.40	GO:0009792	embryo development ending in birth or egg hatching
0.40	GO:0030299	intestinal cholesterol absorption
0.39	GO:0035265	organ growth
0.38	GO:1904888	cranial skeletal system development

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0004427	inorganic diphosphatase activity
0.36	GO:0000287	magnesium ion binding
0.34	GO:0003924	GTPase activity
0.34	GO:0005515	protein binding
0.33	GO:0004930	G-protein coupled receptor activity

0.70	GO:0005794	Golgi apparatus
0.69	GO:0005783	endoplasmic reticulum
0.44	GO:0012507	ER to Golgi transport vesicle membrane
0.43	GO:0030120	vesicle coat
0.42	GO:0031984	organelle subcompartment
0.37	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0016528	sarcoplasm
0.34	GO:0070062	extracellular exosome
0.34	GO:0044233	ER-mitochondrion membrane contact site
0.33	GO:0005829	cytosol

0.39	EC:3.6.1.1	GO:0004427
0.39	KEGG:R00004	GO:0004427

tr|T1FMQ6|T1FMQ6_HELRO
Uncharacterized protein
Search

ECHDC3

0.94	Enoyl-CoA hydratase domain-containing protein 3, mitochondrial

0.30

GO:0008152

metabolic process

0.35	GO:0016853	isomerase activity
0.34	GO:0004300	enoyl-CoA hydratase activity
0.33	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups

0.43

GO:0005739

mitochondrion

0.35

EC:5

GO:0016853

tr|T1FMQ7|T1FMQ7_HELRO
Uncharacterized protein
Search

RPS19

0.56	Small subunit ribosomal protein S19e

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.43	GO:0035283	central nervous system segmentation
0.43	GO:0030218	erythrocyte differentiation
0.43	GO:0020027	hemoglobin metabolic process
0.42	GO:0045646	regulation of erythrocyte differentiation
0.42	GO:0000028	ribosomal small subunit assembly
0.42	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator

0.64	GO:0003735	structural constituent of ribosome
0.36	GO:0017134	fibroblast growth factor binding
0.35	GO:0019901	protein kinase binding
0.35	GO:0042803	protein homodimerization activity
0.32	GO:0016787	hydrolase activity

0.61	GO:0005840	ribosome
0.39	GO:0044445	cytosolic part
0.36	GO:0044446	intracellular organelle part
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0005634	nucleus
0.33	GO:0005794	Golgi apparatus
0.30	GO:0016021	integral component of membrane

0.32

GO:0016787

tr|T1FMQ8|T1FMQ8_HELRO
Uncharacterized protein
Search

tr|T1FMQ9|T1FMQ9_HELRO
Uncharacterized protein
Search

NTMT1

0.33	Phosphoethanolamine N-methyltransferase

0.85	GO:0006480	N-terminal protein amino acid methylation
0.47	GO:0018208	peptidyl-proline modification
0.47	GO:0018194	peptidyl-alanine modification
0.45	GO:0016571	histone methylation
0.45	GO:0018201	peptidyl-glycine modification
0.44	GO:0018209	peptidyl-serine modification
0.43	GO:0007051	spindle organization
0.42	GO:0002181	cytoplasmic translation
0.41	GO:0007059	chromosome segregation
0.36	GO:0031167	rRNA methylation

0.63	GO:0008168	methyltransferase activity
0.43	GO:0140096	catalytic activity, acting on a protein
0.36	GO:0140102	catalytic activity, acting on a rRNA
0.32	GO:0005515	protein binding
0.32	GO:0003676	nucleic acid binding

0.43	GO:0005829	cytosol
0.40	GO:0005634	nucleus
0.38	GO:0031974	membrane-enclosed lumen
0.36	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.63

GO:0008168

tr|T1FMR0|T1FMR0_HELRO
Uncharacterized protein
Search

TMEM86A

0.94	Transmembrane protein 86A

0.33

GO:0098655

cation transmembrane transport

0.33

GO:0008324

cation transmembrane transporter activity

0.30

GO:0044425

membrane part

tr|T1FMR1|T1FMR1_HELRO
Secretory carrier-associated membrane protein
Search

0.65	Secretory carrier-associated membrane protein (Fragment)

0.65	GO:0015031	protein transport
0.45	GO:0045956	positive regulation of calcium ion-dependent exocytosis
0.44	GO:0050715	positive regulation of cytokine secretion
0.43	GO:0045806	negative regulation of endocytosis
0.42	GO:0034976	response to endoplasmic reticulum stress
0.36	GO:0006887	exocytosis
0.33	GO:0006897	endocytosis
0.33	GO:0046907	intracellular transport
0.33	GO:0034613	cellular protein localization
0.33	GO:0006892	post-Golgi vesicle-mediated transport

0.35	GO:0005515	protein binding
0.33	GO:0008565	protein transporter activity
0.30	GO:0003824	catalytic activity

0.48	GO:0055038	recycling endosome membrane
0.47	GO:0032588	trans-Golgi network membrane
0.42	GO:0031201	SNARE complex
0.39	GO:0030133	transport vesicle
0.37	GO:0005886	plasma membrane
0.36	GO:0099503	secretory vesicle
0.36	GO:0098793	presynapse
0.36	GO:0030659	cytoplasmic vesicle membrane
0.36	GO:0030054	cell junction
0.35	GO:0070062	extracellular exosome

tr|T1FMR2|T1FMR2_HELRO
Uncharacterized protein
Search

HAAO

0.59	3-hydroxyanthranilate 3,4-dioxygenase

0.73	GO:0043420	anthranilate metabolic process
0.73	GO:0034354	'de novo' NAD biosynthetic process from tryptophan
0.70	GO:0019805	quinolinate biosynthetic process
0.69	GO:0006569	tryptophan catabolic process
0.53	GO:0055114	oxidation-reduction process
0.48	GO:0070050	neuron cellular homeostasis
0.47	GO:0010043	response to zinc ion
0.46	GO:0046686	response to cadmium ion

0.85	GO:0000334	3-hydroxyanthranilate 3,4-dioxygenase activity
0.71	GO:0008198	ferrous iron binding
0.33	GO:0016831	carboxy-lyase activity
0.32	GO:0016787	hydrolase activity

0.44	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.85	EC:1.13.11.6	GO:0000334
0.85	KEGG:R02665	GO:0000334

tr|T1FMR3|T1FMR3_HELRO
Uncharacterized protein
Search

SRRT

0.86	Serrate RNA effector molecule

0.65	GO:0031053	primary miRNA processing
0.62	GO:0097150	neuronal stem cell population maintenance
0.58	GO:0008283	cell proliferation
0.56	GO:0050769	positive regulation of neurogenesis
0.45	GO:2001141	regulation of RNA biosynthetic process
0.43	GO:0032515	negative regulation of phosphoprotein phosphatase activity
0.37	GO:0042795	snRNA transcription by RNA polymerase II
0.37	GO:0046685	response to arsenic-containing substance
0.36	GO:0000398	mRNA splicing, via spliceosome

0.51	GO:0003676	nucleic acid binding
0.44	GO:0004865	protein serine/threonine phosphatase inhibitor activity
0.36	GO:0005515	protein binding

0.54	GO:0005654	nucleoplasm
0.46	GO:0043234	protein complex
0.41	GO:0005737	cytoplasm

tr|T1FMR4|T1FMR4_HELRO
Catalase
Search

0.54

Catalase

0.73	GO:0042744	hydrogen peroxide catabolic process
0.71	GO:0006979	response to oxidative stress
0.69	GO:0098869	cellular oxidant detoxification
0.52	GO:0055114	oxidation-reduction process
0.45	GO:0038001	paracrine signaling
0.44	GO:0036335	intestinal stem cell homeostasis
0.44	GO:0035206	regulation of hemocyte proliferation
0.43	GO:0045471	response to ethanol
0.42	GO:0003007	heart morphogenesis
0.42	GO:0034976	response to endoplasmic reticulum stress

0.77	GO:0004096	catalase activity
0.63	GO:0020037	heme binding
0.53	GO:0046872	metal ion binding
0.33	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups

0.34	GO:0005777	peroxisome
0.33	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.77

EC:1.11.1.6

GO:0004096

tr|T1FMR5|T1FMR5_HELRO
Uncharacterized protein
Search

GNL1

0.90	LOW QUALITY PROTEIN: guanine nucleotide-binding protein-like 1

0.43	GO:0006974	cellular response to DNA damage stimulus
0.42	GO:0042254	ribosome biogenesis
0.35	GO:0002456	T cell mediated immunity
0.33	GO:0007165	signal transduction

0.66	GO:0001883	purine nucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.65	GO:0032549	ribonucleoside binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0003924	GTPase activity
0.33	GO:0005198	structural molecule activity

0.34	GO:0005634	nucleus
0.34	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

tr|T1FMR6|T1FMR6_HELRO
Uncharacterized protein
Search

0.65	Heterogeneous nuclear ribonucleoprotein L

0.67	GO:0006397	mRNA processing
0.48	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.35	GO:1902416	positive regulation of mRNA binding
0.35	GO:0048025	negative regulation of mRNA splicing, via spliceosome
0.35	GO:0034198	cellular response to amino acid starvation
0.34	GO:0007623	circadian rhythm
0.34	GO:1901652	response to peptide
0.34	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
0.34	GO:0045727	positive regulation of translation

0.57	GO:0003723	RNA binding
0.40	GO:0044212	transcription regulatory region DNA binding
0.35	GO:0005515	protein binding
0.33	GO:0008270	zinc ion binding
0.30	GO:0003824	catalytic activity

0.61	GO:0019013	viral nucleocapsid
0.59	GO:0005634	nucleus
0.54	GO:0030529	intracellular ribonucleoprotein complex
0.39	GO:0031974	membrane-enclosed lumen
0.37	GO:0044446	intracellular organelle part
0.37	GO:0043232	intracellular non-membrane-bounded organelle
0.36	GO:0070062	extracellular exosome
0.34	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|T1FMR7|T1FMR7_HELRO
Uncharacterized protein
Search

0.69	Transcription initiation factor IIA subunit 1

0.79	GO:0006367	transcription initiation from RNA polymerase II promoter
0.60	GO:0006413	translational initiation
0.38	GO:0036465	synaptic vesicle recycling
0.37	GO:2001141	regulation of RNA biosynthetic process
0.37	GO:0030100	regulation of endocytosis
0.36	GO:0006897	endocytosis
0.34	GO:0042795	snRNA transcription by RNA polymerase II
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression
0.34	GO:0006368	transcription elongation from RNA polymerase II promoter

0.60	GO:0003743	translation initiation factor activity
0.50	GO:0001103	RNA polymerase II repressing transcription factor binding
0.47	GO:0017025	TBP-class protein binding
0.45	GO:0046982	protein heterodimerization activity
0.42	GO:0003713	transcription coactivator activity
0.38	GO:0003677	DNA binding

0.83	GO:0005672	transcription factor TFIIA complex
0.47	GO:0005669	transcription factor TFIID complex
0.43	GO:0005829	cytosol
0.37	GO:0098793	presynapse
0.30	GO:0016020	membrane

tr|T1FMR8|T1FMR8_HELRO
Importin subunit alpha
Search

0.39	Importin subunit alpha

0.78

GO:0006606

protein import into nucleus

0.80	GO:0061608	nuclear import signal receptor activity
0.40	GO:0008139	nuclear localization sequence binding
0.38	GO:0008565	protein transporter activity

0.59	GO:0005634	nucleus
0.47	GO:0005737	cytoplasm
0.37	GO:0012505	endomembrane system
0.37	GO:0031974	membrane-enclosed lumen
0.36	GO:0031967	organelle envelope
0.35	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

tr|T1FMR9|T1FMR9_HELRO
Dipeptidase
Search

0.56	Membrane dipeptidase

0.60	GO:0006508	proteolysis
0.38	GO:0048589	developmental growth

0.76	GO:0016805	dipeptidase activity
0.66	GO:0008237	metallopeptidase activity
0.64	GO:0008239	dipeptidyl-peptidase activity
0.53	GO:0046872	metal ion binding

0.71	GO:0031225	anchored component of membrane
0.30	GO:0016021	integral component of membrane

0.76

EC:3.4.13

GO:0016805

tr|T1FMS0|T1FMS0_HELRO
Uncharacterized protein
Search

YKT6

0.88	Synaptobrevin homolog YKT6-A

0.69	GO:0016192	vesicle-mediated transport
0.47	GO:0051650	establishment of vesicle localization
0.47	GO:0016482	cytosolic transport
0.46	GO:0140056	organelle localization by membrane tethering
0.46	GO:0016197	endosomal transport
0.46	GO:0090174	organelle membrane fusion
0.45	GO:0032940	secretion by cell
0.45	GO:0016050	vesicle organization
0.37	GO:0015031	protein transport
0.34	GO:0042144	vacuole fusion, non-autophagic

0.50	GO:0005484	SNAP receptor activity
0.47	GO:0045296	cadherin binding
0.47	GO:0016409	palmitoyltransferase activity
0.47	GO:0019707	protein-cysteine S-acyltransferase activity
0.45	GO:0000149	SNARE binding
0.34	GO:0004683	calmodulin-dependent protein kinase activity
0.34	GO:0005516	calmodulin binding
0.33	GO:0005261	cation channel activity

0.46	GO:0031201	SNARE complex
0.46	GO:0005768	endosome
0.45	GO:0005794	Golgi apparatus
0.44	GO:0005829	cytosol
0.44	GO:0005783	endoplasmic reticulum
0.42	GO:0005887	integral component of plasma membrane
0.41	GO:0005739	mitochondrion
0.39	GO:0097441	basal dendrite
0.39	GO:0097440	apical dendrite
0.39	GO:0030659	cytoplasmic vesicle membrane

0.47

GO:0016409

tr|T1FMS1|T1FMS1_HELRO
Uncharacterized protein
Search

WWOX

0.80	WW domain containing oxidoreductase

0.78	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
0.74	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator
0.73	GO:0097191	extrinsic apoptotic signaling pathway
0.73	GO:0001649	osteoblast differentiation
0.72	GO:0030178	negative regulation of Wnt signaling pathway
0.71	GO:0071560	cellular response to transforming growth factor beta stimulus
0.71	GO:0048705	skeletal system morphogenesis
0.66	GO:0006366	transcription by RNA polymerase II
0.65	GO:0045944	positive regulation of transcription by RNA polymerase II
0.52	GO:0050829	defense response to Gram-negative bacterium

0.74	GO:0001105	RNA polymerase II transcription coactivator activity
0.62	GO:0019899	enzyme binding
0.47	GO:0016491	oxidoreductase activity
0.37	GO:0046983	protein dimerization activity
0.35	GO:0050662	coenzyme binding

0.73	GO:0005902	microvillus
0.66	GO:0090575	RNA polymerase II transcription factor complex
0.63	GO:0005794	Golgi apparatus
0.60	GO:0005829	cytosol
0.54	GO:0005739	mitochondrion
0.50	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.47

GO:0016491

tr|T1FMS2|T1FMS2_HELRO
Uncharacterized protein
Search

0.86	GO:0044719	regulation of imaginal disc-derived wing size
0.86	GO:0008039	synaptic target recognition
0.86	GO:0016203	muscle attachment

0.70

GO:0005509

calcium ion binding

0.86

GO:0005927

muscle tendon junction

tr|T1FMS3|T1FMS3_HELRO
Uncharacterized protein
Search

GPT2

0.87	Glutamic--pyruvic transaminase

0.69	GO:0006103	2-oxoglutarate metabolic process
0.68	GO:0042851	L-alanine metabolic process
0.49	GO:0009058	biosynthetic process

0.71	GO:0047635	alanine-oxo-acid transaminase activity
0.67	GO:0030170	pyridoxal phosphate binding

0.53	GO:0005739	mitochondrion
0.39	GO:0005615	extracellular space

0.71

EC:2.6.1.12

GO:0047635

tr|T1FMS4|T1FMS4_HELRO
Uncharacterized protein
Search

SLC25A37

0.48	Mitochondrial substrate/solute carrier

0.45	GO:0055085	transmembrane transport
0.45	GO:0048250	mitochondrial iron ion transport
0.40	GO:0055072	iron ion homeostasis
0.38	GO:0006421	asparaginyl-tRNA aminoacylation
0.35	GO:0006914	autophagy
0.34	GO:0006413	translational initiation
0.34	GO:0015031	protein transport

0.42	GO:0005381	iron ion transmembrane transporter activity
0.38	GO:0004816	asparagine-tRNA ligase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0003743	translation initiation factor activity
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.38	GO:0031090	organelle membrane
0.38	GO:0005740	mitochondrial envelope
0.34	GO:0044433	cytoplasmic vesicle part
0.34	GO:0005794	Golgi apparatus
0.30	GO:0031224	intrinsic component of membrane

0.38	EC:6.1.1.22	GO:0004816
0.38	KEGG:R03648	GO:0004816

tr|T1FMS5|T1FMS5_HELRO
Annexin
Search

ANXA13

0.47

Annexin

0.48	GO:2000483	negative regulation of interleukin-8 secretion
0.46	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.45	GO:0007219	Notch signaling pathway
0.45	GO:0030855	epithelial cell differentiation
0.42	GO:0006357	regulation of transcription by RNA polymerase II
0.37	GO:0051592	response to calcium ion
0.37	GO:0006909	phagocytosis
0.36	GO:0032506	cytokinetic process
0.35	GO:0009414	response to water deprivation
0.35	GO:0009651	response to salt stress

0.81	GO:0005544	calcium-dependent phospholipid binding
0.70	GO:0005509	calcium ion binding
0.48	GO:0048306	calcium-dependent protein binding
0.47	GO:0051059	NF-kappaB binding
0.43	GO:0042802	identical protein binding
0.39	GO:0008429	phosphatidylethanolamine binding
0.38	GO:0044548	S100 protein binding
0.34	GO:0023026	MHC class II protein complex binding
0.34	GO:0035374	chondroitin sulfate binding
0.34	GO:0004859	phospholipase inhibitor activity

0.45	GO:0005635	nuclear envelope
0.44	GO:0048471	perinuclear region of cytoplasm
0.44	GO:0012506	vesicle membrane
0.43	GO:0009986	cell surface
0.39	GO:0005886	plasma membrane
0.39	GO:0005654	nucleoplasm
0.38	GO:0005766	primary lysosome
0.38	GO:0042581	specific granule
0.37	GO:0045335	phagocytic vesicle
0.37	GO:0030496	midbody

tr|T1FMS6|T1FMS6_HELRO
Uncharacterized protein
Search

0.45	Glycine cleavage system protein H

0.77	GO:0019464	glycine decarboxylation via glycine cleavage system
0.34	GO:0035246	peptidyl-arginine N-methylation
0.33	GO:0009249	protein lipoylation
0.33	GO:0006730	one-carbon metabolic process
0.32	GO:0055114	oxidation-reduction process

0.34	GO:0016642	oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor
0.33	GO:0004386	helicase activity
0.33	GO:0008168	methyltransferase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003676	nucleic acid binding

0.78	GO:0005960	glycine cleavage complex
0.48	GO:0005739	mitochondrion
0.32	GO:0005840	ribosome

0.34

EC:1.4.4

GO:0016642

tr|T1FMS7|T1FMS7_HELRO
Uncharacterized protein
Search

tr|T1FMS8|T1FMS8_HELRO
Uncharacterized protein
Search

0.58	ADP ribosylation factor

0.37	GO:0032482	Rab protein signal transduction
0.34	GO:0016192	vesicle-mediated transport
0.34	GO:0015991	ATP hydrolysis coupled proton transport

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0004767	sphingomyelin phosphodiesterase activity
0.34	GO:0005515	protein binding
0.33	GO:0015078	hydrogen ion transmembrane transporter activity

0.44	GO:0005794	Golgi apparatus
0.44	GO:0043025	neuronal cell body
0.42	GO:0045202	synapse
0.36	GO:0005770	late endosome
0.34	GO:0033179	proton-transporting V-type ATPase, V0 domain
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.34	EC:3.1.4.12	GO:0004767
0.34	KEGG:R02541	GO:0004767

tr|T1FMS9|T1FMS9_HELRO
Uncharacterized protein
Search

UBE2W

0.47	Ubiquitin-conjugating enzyme

0.57	GO:0000209	protein polyubiquitination
0.55	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.46	GO:0006513	protein monoubiquitination
0.46	GO:0046854	phosphatidylinositol phosphorylation
0.40	GO:0071218	cellular response to misfolded protein
0.40	GO:0009253	peptidoglycan catabolic process
0.39	GO:0006515	protein quality control for misfolded or incompletely synthesized proteins
0.38	GO:0046416	D-amino acid metabolic process
0.36	GO:0006281	DNA repair
0.34	GO:0055114	oxidation-reduction process

0.56	GO:0031625	ubiquitin protein ligase binding
0.54	GO:0061630	ubiquitin protein ligase activity
0.46	GO:0016874	ligase activity
0.41	GO:0008144	drug binding
0.41	GO:0043168	anion binding
0.41	GO:0032559	adenyl ribonucleotide binding
0.40	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity
0.39	GO:0003884	D-amino-acid oxidase activity
0.37	GO:0008270	zinc ion binding
0.37	GO:0050662	coenzyme binding

0.47	GO:0005634	nucleus
0.40	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.46

GO:0016874

tr|T1FMT0|T1FMT0_HELRO
Eukaryotic translation initiation factor 3 subunit I
Search

EIF3I

0.68	Eukaryotic translation initiation factor 3 subunit I

0.72	GO:0006413	translational initiation
0.70	GO:0002181	cytoplasmic translation
0.69	GO:0006446	regulation of translational initiation
0.66	GO:0022618	ribonucleoprotein complex assembly
0.41	GO:0002040	sprouting angiogenesis
0.40	GO:0001889	liver development
0.35	GO:0035556	intracellular signal transduction

0.72	GO:0003743	translation initiation factor activity
0.35	GO:0005515	protein binding

0.78	GO:0005852	eukaryotic translation initiation factor 3 complex
0.70	GO:0016282	eukaryotic 43S preinitiation complex
0.70	GO:0033290	eukaryotic 48S preinitiation complex
0.36	GO:0070062	extracellular exosome
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

tr|T1FMT1|T1FMT1_HELRO
Uncharacterized protein
Search

0.69	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like

0.45	GO:0051220	cytoplasmic sequestering of protein
0.44	GO:0040024	dauer larval development
0.44	GO:0046823	negative regulation of nucleocytoplasmic transport
0.44	GO:1904590	negative regulation of protein import
0.44	GO:1900181	negative regulation of protein localization to nucleus
0.43	GO:0042306	regulation of protein import into nucleus
0.37	GO:0007095	mitotic G2 DNA damage checkpoint
0.36	GO:0051172	negative regulation of nitrogen compound metabolic process
0.36	GO:0031324	negative regulation of cellular metabolic process
0.36	GO:0043086	negative regulation of catalytic activity

0.77	GO:0019904	protein domain specific binding
0.40	GO:0008134	transcription factor binding
0.36	GO:0004497	monooxygenase activity
0.36	GO:0004857	enzyme inhibitor activity
0.35	GO:0019887	protein kinase regulator activity
0.35	GO:0032038	myosin II heavy chain binding
0.35	GO:0042802	identical protein binding
0.34	GO:0047485	protein N-terminus binding
0.34	GO:0051219	phosphoprotein binding
0.34	GO:0045296	cadherin binding

0.39	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm
0.35	GO:0032153	cell division site
0.34	GO:0015630	microtubule cytoskeleton
0.34	GO:0044430	cytoskeletal part
0.34	GO:0070938	contractile ring
0.34	GO:0051286	cell tip
0.34	GO:0015629	actin cytoskeleton
0.33	GO:0071944	cell periphery
0.33	GO:0097708	intracellular vesicle

tr|T1FMT2|T1FMT2_HELRO
Peptidylprolyl isomerase
Search

0.41	Peptidyl-prolyl cis-trans isomerase

0.71	GO:0000413	protein peptidyl-prolyl isomerization
0.40	GO:0061077	chaperone-mediated protein folding

0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.42	GO:0005528	FK506 binding

0.35	GO:0005737	cytoplasm
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.72

GO:0003755

tr|T1FMT3|T1FMT3_HELRO
Uncharacterized protein
Search

ACTR3

0.84	actin-related protein 3

0.81	GO:0034314	Arp2/3 complex-mediated actin nucleation
0.54	GO:0016344	meiotic chromosome movement towards spindle pole
0.52	GO:0033206	meiotic cytokinesis
0.51	GO:0071346	cellular response to interferon-gamma
0.51	GO:0008356	asymmetric cell division
0.51	GO:0051653	spindle localization
0.49	GO:0060271	cilium assembly
0.49	GO:0007163	establishment or maintenance of cell polarity
0.36	GO:1905836	response to triterpenoid
0.36	GO:1905834	response to pyrimidine ribonucleotide

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0051015	actin filament binding
0.48	GO:0005200	structural constituent of cytoskeleton
0.35	GO:0051117	ATPase binding

0.80	GO:0005885	Arp2/3 protein complex
0.51	GO:0030027	lamellipodium
0.51	GO:0005903	brush border
0.48	GO:0005911	cell-cell junction
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.36	GO:0061830	concave side of sperm head
0.36	GO:0061828	apical tubulobulbar complex
0.35	GO:0061825	podosome core
0.35	GO:0030056	hemidesmosome

tr|T1FMT4|T1FMT4_HELRO
Uncharacterized protein
Search

PHKG2

0.69	Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart

0.75	GO:0005978	glycogen biosynthetic process
0.63	GO:0006468	protein phosphorylation
0.47	GO:0018210	peptidyl-threonine modification
0.46	GO:0018209	peptidyl-serine modification
0.40	GO:0035556	intracellular signal transduction
0.40	GO:0001525	angiogenesis
0.35	GO:0045819	positive regulation of glycogen catabolic process
0.35	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.34	GO:0006289	nucleotide-excision repair
0.34	GO:0005980	glycogen catabolic process

0.85	GO:0004689	phosphorylase kinase activity
0.78	GO:0005516	calmodulin binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0050321	tau-protein kinase activity
0.36	GO:0019899	enzyme binding
0.34	GO:0003684	damaged DNA binding
0.33	GO:0046983	protein dimerization activity

0.85	GO:0005964	phosphorylase kinase complex
0.44	GO:0005829	cytosol
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.85

EC:2.7.11.19

GO:0004689

tr|T1FMT5|T1FMT5_HELRO
Uncharacterized protein
Search

0.82	Apoptosis regulator Bcl-2

0.74	GO:0042981	regulation of apoptotic process
0.47	GO:0006915	apoptotic process

0.30

GO:0044425

membrane part

tr|T1FMT6|T1FMT6_HELRO
Uncharacterized protein
Search

tr|T1FMT7|T1FMT7_HELRO
Mothers against decapentaplegic homolog
Search

0.62	Mothers against decapentaplegic homolog

0.78	GO:0007179	transforming growth factor beta receptor signaling pathway
0.57	GO:0006355	regulation of transcription, DNA-templated
0.55	GO:0006351	transcription, DNA-templated
0.38	GO:0051481	negative regulation of cytosolic calcium ion concentration
0.38	GO:0033689	negative regulation of osteoblast proliferation
0.38	GO:0038092	nodal signaling pathway
0.38	GO:0007183	SMAD protein complex assembly
0.38	GO:1901203	positive regulation of extracellular matrix assembly
0.38	GO:0048617	embryonic foregut morphogenesis
0.38	GO:0032909	regulation of transforming growth factor beta2 production

0.59	GO:0003700	DNA binding transcription factor activity
0.53	GO:0003677	DNA binding
0.39	GO:0031962	mineralocorticoid receptor binding
0.39	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
0.38	GO:0035259	glucocorticoid receptor binding
0.38	GO:0017151	DEAD/H-box RNA helicase binding
0.38	GO:0070410	co-SMAD binding
0.38	GO:0070878	primary miRNA binding
0.38	GO:0070412	R-SMAD binding
0.38	GO:0043425	bHLH transcription factor binding

0.71	GO:0005667	transcription factor complex
0.59	GO:0005634	nucleus
0.47	GO:0005737	cytoplasm
0.38	GO:0071141	SMAD protein complex
0.37	GO:0043235	receptor complex
0.36	GO:0000785	chromatin
0.35	GO:0012505	endomembrane system
0.35	GO:0070013	intracellular organelle lumen
0.35	GO:0019866	organelle inner membrane
0.34	GO:0005886	plasma membrane

tr|T1FMT8|T1FMT8_HELRO
Uncharacterized protein
Search

NSDHL

0.94	sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating

0.78	GO:0006694	steroid biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.50	GO:0060716	labyrinthine layer blood vessel development
0.50	GO:0007224	smoothened signaling pathway
0.50	GO:0008203	cholesterol metabolic process
0.49	GO:0001942	hair follicle development
0.47	GO:0001878	response to yeast
0.41	GO:1902653	secondary alcohol biosynthetic process
0.38	GO:0008204	ergosterol metabolic process
0.38	GO:0044108	cellular alcohol biosynthetic process

0.82	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity
0.42	GO:0000252	C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity
0.41	GO:0103067	4alpha-carboxy-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-dehydrogenase (decarboxylating) activity
0.41	GO:0103066	4alpha-carboxy-4beta-methyl-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-oxidoreductase (decarboxylating) activity
0.41	GO:0047012	sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity
0.33	GO:0020037	heme binding
0.32	GO:0050662	coenzyme binding
0.32	GO:0046872	metal ion binding
0.32	GO:0016853	isomerase activity

0.52	GO:0005811	lipid droplet
0.48	GO:0005783	endoplasmic reticulum
0.40	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.39	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.82

EC:1.1.1.145

GO:0003854

tr|T1FMT9|T1FMT9_HELRO
Uncharacterized protein
Search

0.40	GO:0070828	heterochromatin organization
0.38	GO:0016246	RNA interference
0.36	GO:0051567	histone H3-K9 methylation
0.36	GO:0042981	regulation of apoptotic process
0.36	GO:0031935	regulation of chromatin silencing
0.35	GO:0006796	phosphate-containing compound metabolic process
0.34	GO:0043488	regulation of mRNA stability
0.32	GO:0006508	proteolysis

0.77	GO:0003730	mRNA 3'-UTR binding
0.49	GO:0045296	cadherin binding
0.39	GO:0004427	inorganic diphosphatase activity
0.36	GO:0000287	magnesium ion binding
0.33	GO:0070008	serine-type exopeptidase activity
0.33	GO:0004252	serine-type endopeptidase activity

0.44	GO:0005829	cytosol
0.43	GO:0005634	nucleus
0.41	GO:0005703	polytene chromosome puff
0.38	GO:0016442	RISC complex
0.36	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0005701	polytene chromosome chromocenter
0.36	GO:0070062	extracellular exosome
0.34	GO:0005886	plasma membrane

0.39	EC:3.6.1.1	GO:0004427
0.39	KEGG:R00004	GO:0004427

tr|T1FMU0|T1FMU0_HELRO
Uncharacterized protein
Search

0.85	ATPase family AAA domain-containing protein 3-A

0.34

GO:0006508

proteolysis

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0008233	peptidase activity

0.39	GO:0031966	mitochondrial membrane
0.39	GO:0019866	organelle inner membrane
0.38	GO:0042645	mitochondrial nucleoid
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0008233

tr|T1FMU1|T1FMU1_HELRO
Eukaryotic translation initiation factor 3 subunit L
Search

EIF3L

0.71	Eukaryotic translation initiation factor 3 subunit L

0.73	GO:0001731	formation of translation preinitiation complex
0.72	GO:0006446	regulation of translational initiation
0.52	GO:0075525	viral translational termination-reinitiation
0.36	GO:0032456	endocytic recycling

0.72	GO:0003743	translation initiation factor activity
0.36	GO:0017137	Rab GTPase binding
0.33	GO:0046872	metal ion binding

0.77	GO:0005852	eukaryotic translation initiation factor 3 complex
0.72	GO:0016282	eukaryotic 43S preinitiation complex
0.72	GO:0033290	eukaryotic 48S preinitiation complex
0.49	GO:0001650	fibrillar center
0.45	GO:0005654	nucleoplasm
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

tr|T1FMU2|T1FMU2_HELRO
Uncharacterized protein
Search

0.75	WD repeat domain phosphoinositide-interacting protein 4

0.74	GO:0006914	autophagy
0.56	GO:0061726	mitochondrion disassembly
0.54	GO:0007033	vacuole organization
0.53	GO:0006497	protein lipidation
0.50	GO:0070925	organelle assembly
0.48	GO:0034613	cellular protein localization
0.38	GO:0015031	protein transport

0.60	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding
0.59	GO:0032266	phosphatidylinositol-3-phosphate binding
0.46	GO:0010314	phosphatidylinositol-5-phosphate binding
0.45	GO:0070273	phosphatidylinositol-4-phosphate binding
0.40	GO:0032559	adenyl ribonucleotide binding
0.40	GO:0008144	drug binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0005509	calcium ion binding
0.39	GO:0004386	helicase activity
0.39	GO:0003676	nucleic acid binding

0.56	GO:0034045	phagophore assembly site membrane
0.55	GO:0019898	extrinsic component of membrane
0.48	GO:0005829	cytosol
0.45	GO:0005773	vacuole
0.43	GO:0005768	endosome
0.40	GO:0098588	bounding membrane of organelle
0.38	GO:0044433	cytoplasmic vesicle part
0.36	GO:0012506	vesicle membrane
0.30	GO:0016021	integral component of membrane

tr|T1FMU3|T1FMU3_HELRO
Uncharacterized protein
Search

PSMD12

0.85	26S proteasome non-ATPase regulatory subunit 12

0.47	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.45	GO:1904888	cranial skeletal system development
0.44	GO:0001822	kidney development
0.43	GO:0007420	brain development
0.36	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.36	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.35	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation

0.71	GO:1905369	endopeptidase complex
0.58	GO:0043234	protein complex
0.44	GO:0044424	intracellular part
0.44	GO:0031974	membrane-enclosed lumen
0.40	GO:0044422	organelle part
0.40	GO:0043227	membrane-bounded organelle
0.36	GO:0043230	extracellular organelle
0.35	GO:0005615	extracellular space
0.33	GO:0012505	endomembrane system
0.30	GO:0016020	membrane

tr|T1FMU4|T1FMU4_HELRO
Tryptophan 2,3-dioxygenase
Search

0.62	Tryptophan 2,3-dioxygenase

0.78	GO:0019441	tryptophan catabolic process to kynurenine
0.67	GO:0033060	ocellus pigmentation
0.67	GO:0006726	eye pigment biosynthetic process
0.57	GO:0044550	secondary metabolite biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.51	GO:0051289	protein homotetramerization
0.46	GO:0019442	tryptophan catabolic process to acetyl-CoA
0.45	GO:0018130	heterocycle biosynthetic process
0.45	GO:1901362	organic cyclic compound biosynthetic process
0.45	GO:0019438	aromatic compound biosynthetic process

0.83	GO:0004833	tryptophan 2,3-dioxygenase activity
0.63	GO:0020037	heme binding
0.54	GO:0046872	metal ion binding
0.41	GO:0042802	identical protein binding
0.38	GO:0008234	cysteine-type peptidase activity
0.34	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.34	GO:0019825	oxygen binding
0.34	GO:0016597	amino acid binding

0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.83

EC:1.13.11.11

GO:0004833

tr|T1FMU5|T1FMU5_HELRO
Histone H3
Search

0.43	GO:0006334	nucleosome assembly
0.37	GO:0007140	male meiotic nuclear division
0.36	GO:0034724	DNA replication-independent nucleosome organization
0.36	GO:0030307	positive regulation of cell growth

0.74	GO:0046982	protein heterodimerization activity
0.55	GO:0003677	DNA binding
0.45	GO:0031491	nucleosome binding
0.39	GO:0098770	FBXO family protein binding
0.35	GO:0001067	regulatory region nucleic acid binding

0.75	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.37	GO:0005700	polytene chromosome
0.35	GO:0000781	chromosome, telomeric region
0.34	GO:0043233	organelle lumen
0.33	GO:0043234	protein complex

tr|T1FMU6|T1FMU6_HELRO
Uncharacterized protein
Search

0.51	Cell division control protein 2 cognate

0.63	GO:0006468	protein phosphorylation
0.46	GO:0044772	mitotic cell cycle phase transition
0.46	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.46	GO:0044843	cell cycle G1/S phase transition
0.45	GO:0007284	spermatogonial cell division
0.45	GO:0048142	germarium-derived cystoblast division
0.44	GO:0055059	asymmetric neuroblast division
0.44	GO:0046427	positive regulation of JAK-STAT cascade
0.44	GO:0044839	cell cycle G2/M phase transition
0.44	GO:0140013	meiotic nuclear division

0.68	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0097472	cyclin-dependent protein kinase activity
0.38	GO:0030332	cyclin binding
0.38	GO:0000993	RNA polymerase II core binding
0.37	GO:0019912	cyclin-dependent protein kinase activating kinase activity
0.37	GO:0042393	histone binding

0.41	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.40	GO:0072686	mitotic spindle
0.38	GO:0005634	nucleus
0.38	GO:0000235	astral microtubule
0.37	GO:0005816	spindle pole body
0.37	GO:0005935	cellular bud neck
0.37	GO:0010494	cytoplasmic stress granule
0.37	GO:0051233	spindle midzone
0.36	GO:0005783	endoplasmic reticulum
0.35	GO:0070013	intracellular organelle lumen

0.68	EC:2.7.11	GO:0004674
0.34	KEGG:R00425	GO:0003935

tr|T1FMU7|T1FMU7_HELRO
Uncharacterized protein
Search

0.42	Voltage-dependent anion-selective channel

0.69	GO:0098656	anion transmembrane transport
0.46	GO:0030382	sperm mitochondrion organization
0.45	GO:0031101	fin regeneration
0.45	GO:0007291	sperm individualization
0.42	GO:0007602	phototransduction
0.42	GO:0036444	mitochondrial calcium uptake
0.41	GO:1902017	regulation of cilium assembly
0.41	GO:0008016	regulation of heart contraction
0.38	GO:0007270	neuron-neuron synaptic transmission
0.38	GO:0001662	behavioral fear response

0.78	GO:0008308	voltage-gated anion channel activity
0.41	GO:0042802	identical protein binding
0.38	GO:0046983	protein dimerization activity
0.37	GO:0044325	ion channel binding
0.36	GO:0019901	protein kinase binding
0.35	GO:0015288	porin activity
0.32	GO:1901265	nucleoside phosphate binding
0.32	GO:0036094	small molecule binding

0.78	GO:0005741	mitochondrial outer membrane
0.46	GO:0016006	Nebenkern
0.38	GO:0005757	mitochondrial permeability transition pore complex
0.38	GO:0042645	mitochondrial nucleoid
0.38	GO:0043209	myelin sheath
0.36	GO:0005886	plasma membrane
0.35	GO:0019866	organelle inner membrane
0.35	GO:0065010	extracellular membrane-bounded organelle
0.34	GO:0001669	acrosomal vesicle

tr|T1FMU8|T1FMU8_HELRO
Uncharacterized protein
Search

0.61	Probable RPP1A-60S large subunit acidic ribosomal protein a1

0.68	GO:0006414	translational elongation
0.41	GO:0042254	ribosome biogenesis
0.38	GO:0002181	cytoplasmic translation

0.62	GO:0003735	structural constituent of ribosome
0.35	GO:0032403	protein complex binding

0.61	GO:0005840	ribosome
0.38	GO:0044445	cytosolic part
0.35	GO:0044446	intracellular organelle part

tr|T1FMU9|T1FMU9_HELRO
Uncharacterized protein
Search

0.56	GO:0035444	nickel cation transmembrane transport
0.49	GO:0009236	cobalamin biosynthetic process
0.48	GO:0007165	signal transduction
0.42	GO:2000274	regulation of epithelial cell migration, open tracheal system
0.42	GO:0010312	detoxification of zinc ion
0.42	GO:0042069	regulation of catecholamine metabolic process
0.41	GO:0007298	border follicle cell migration
0.38	GO:0050790	regulation of catalytic activity
0.36	GO:0006461	protein complex assembly
0.35	GO:0006357	regulation of transcription by RNA polymerase II

0.57	GO:0005230	extracellular ligand-gated ion channel activity
0.56	GO:0015099	nickel cation transmembrane transporter activity
0.54	GO:0004888	transmembrane signaling receptor activity
0.45	GO:0046872	metal ion binding
0.44	GO:0016852	sirohydrochlorin cobaltochelatase activity
0.38	GO:0030234	enzyme regulator activity
0.37	GO:0018822	nitrile hydratase activity
0.36	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.35	GO:0003924	GTPase activity
0.33	GO:0003677	DNA binding

0.43	GO:0005886	plasma membrane
0.41	GO:0097038	perinuclear endoplasmic reticulum
0.40	GO:0008021	synaptic vesicle
0.40	GO:0043025	neuronal cell body
0.40	GO:0030424	axon
0.34	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.44

EC:4.99.1.3

GO:0016852

tr|T1FMV0|T1FMV0_HELRO
Uncharacterized protein
Search

0.83

GO:0032526

response to retinoic acid

0.37	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
0.36	GO:0005515	protein binding
0.36	GO:0016829	lyase activity
0.35	GO:0003676	nucleic acid binding

0.43	GO:0005765	lysosomal membrane
0.37	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.37

GO:0016747

tr|T1FMV1|T1FMV1_HELRO
Uncharacterized protein
Search

0.51	GO:0055114	oxidation-reduction process
0.36	GO:0034650	cortisol metabolic process
0.35	GO:0033555	multicellular organismal response to stress
0.35	GO:0051492	regulation of stress fiber assembly
0.35	GO:0033993	response to lipid
0.35	GO:0042572	retinol metabolic process
0.34	GO:0048513	animal organ development
0.34	GO:1901700	response to oxygen-containing compound
0.34	GO:0046951	ketone body biosynthetic process
0.34	GO:0061008	hepaticobiliary system development

0.52	GO:0016491	oxidoreductase activity
0.33	GO:0005543	phospholipid binding
0.33	GO:0008146	sulfotransferase activity
0.32	GO:0004312	fatty acid synthase activity

0.43	GO:0005654	nucleoplasm
0.41	GO:0005739	mitochondrion
0.40	GO:0031090	organelle membrane
0.40	GO:0031967	organelle envelope
0.35	GO:0005783	endoplasmic reticulum
0.35	GO:0098552	side of membrane
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.52

GO:0016491

tr|T1FMV2|T1FMV2_HELRO
Isocitrate dehydrogenase [NAD] subunit, mitochondrial
Search

0.65	Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial

0.68	GO:0006099	tricarboxylic acid cycle
0.34	GO:0006734	NADH metabolic process
0.34	GO:0006103	2-oxoglutarate metabolic process
0.34	GO:0006102	isocitrate metabolic process

0.82	GO:0004449	isocitrate dehydrogenase (NAD+) activity
0.67	GO:0051287	NAD binding
0.64	GO:0000287	magnesium ion binding

0.59	GO:0005739	mitochondrion
0.37	GO:0043209	myelin sheath
0.35	GO:0045242	isocitrate dehydrogenase complex (NAD+)
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0005634	nucleus
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.82

EC:1.1.1.41

GO:0004449

tr|T1FMV3|T1FMV3_HELRO
Uncharacterized protein
Search

HMGCLL1

0.48	Hydroxymethylglutaryl-CoA lyase YngG

0.64	GO:0046951	ketone body biosynthetic process
0.36	GO:0051262	protein tetramerization
0.35	GO:0007005	mitochondrion organization
0.35	GO:0070542	response to fatty acid
0.34	GO:0001889	liver development
0.34	GO:0007584	response to nutrient
0.34	GO:0042594	response to starvation
0.34	GO:0006629	lipid metabolic process
0.34	GO:0010506	regulation of autophagy
0.34	GO:0006551	leucine metabolic process

0.83	GO:0004419	hydroxymethylglutaryl-CoA lyase activity
0.35	GO:0042803	protein homodimerization activity
0.35	GO:0030145	manganese ion binding
0.35	GO:0005102	receptor binding
0.34	GO:0000062	fatty-acyl-CoA binding
0.34	GO:0000287	magnesium ion binding
0.34	GO:0003852	2-isopropylmalate synthase activity
0.33	GO:0043177	organic acid binding

0.57	GO:0005829	cytosol
0.40	GO:0005739	mitochondrion
0.40	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0005783	endoplasmic reticulum
0.36	GO:0005777	peroxisome
0.35	GO:0044446	intracellular organelle part
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0031090	organelle membrane
0.34	GO:0005615	extracellular space
0.34	GO:0031975	envelope

0.83	EC:4.1.3.4	GO:0004419
0.83	KEGG:R01360	GO:0004419

tr|T1FMV4|T1FMV4_HELRO
Uncharacterized protein
Search

0.59

Annexin

0.63	GO:0050819	negative regulation of coagulation
0.42	GO:0010033	response to organic substance
0.38	GO:0007599	hemostasis
0.37	GO:0042060	wound healing
0.37	GO:0050817	coagulation
0.37	GO:0055074	calcium ion homeostasis
0.36	GO:0072503	cellular divalent inorganic cation homeostasis
0.36	GO:0006816	calcium ion transport
0.35	GO:0006875	cellular metal ion homeostasis
0.35	GO:0006937	regulation of muscle contraction

0.81	GO:0005544	calcium-dependent phospholipid binding
0.70	GO:0005509	calcium ion binding
0.38	GO:0048306	calcium-dependent protein binding
0.36	GO:0015485	cholesterol binding
0.35	GO:0005178	integrin binding
0.35	GO:0004859	phospholipase inhibitor activity
0.35	GO:0005216	ion channel activity
0.35	GO:0022834	ligand-gated channel activity
0.35	GO:0042803	protein homodimerization activity
0.34	GO:0032550	purine ribonucleoside binding

0.48	GO:0072563	endothelial microparticle
0.44	GO:0009897	external side of plasma membrane
0.38	GO:0005654	nucleoplasm
0.37	GO:0031982	vesicle
0.36	GO:0098805	whole membrane
0.36	GO:0098588	bounding membrane of organelle
0.35	GO:0012505	endomembrane system
0.35	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0005764	lysosome
0.35	GO:0044437	vacuolar part

tr|T1FMV5|T1FMV5_HELRO
Uncharacterized protein
Search

RPL4

0.62	Ribosomal protein L4-b

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.35	GO:0003360	brainstem development
0.35	GO:0045773	positive regulation of axon extension
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0071417	cellular response to organonitrogen compound
0.34	GO:0007420	brain development
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane

0.64	GO:0003735	structural constituent of ribosome
0.38	GO:0003723	RNA binding
0.34	GO:0005515	protein binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005840	ribosome
0.42	GO:0005791	rough endoplasmic reticulum
0.41	GO:0044445	cytosolic part
0.37	GO:0005634	nucleus
0.37	GO:0044446	intracellular organelle part
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.35	GO:0031672	A band
0.34	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

tr|T1FMV6|T1FMV6_HELRO
Uncharacterized protein
Search

GTF2H3

0.94	General transcription factor IIH subunit 3

0.73	GO:0006289	nucleotide-excision repair
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.49	GO:0006366	transcription by RNA polymerase II
0.46	GO:0006468	protein phosphorylation
0.40	GO:0043043	peptide biosynthetic process
0.35	GO:0006362	transcription elongation from RNA polymerase I promoter
0.35	GO:0006363	termination of RNA polymerase I transcription
0.35	GO:0006361	transcription initiation from RNA polymerase I promoter

0.55	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity
0.51	GO:0047485	protein N-terminus binding
0.48	GO:0008094	DNA-dependent ATPase activity
0.44	GO:0003684	damaged DNA binding
0.43	GO:0008135	translation factor activity, RNA binding
0.34	GO:0046872	metal ion binding
0.34	GO:0043022	ribosome binding
0.33	GO:0005199	structural constituent of cell wall
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding

0.81	GO:0000439	core TFIIH complex
0.55	GO:0005675	holo TFIIH complex
0.53	GO:0097550	transcriptional preinitiation complex
0.49	GO:0005669	transcription factor TFIID complex
0.38	GO:0000112	nucleotide-excision repair factor 3 complex
0.34	GO:0005759	mitochondrial matrix
0.33	GO:0009277	fungal-type cell wall
0.33	GO:0031966	mitochondrial membrane
0.33	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.55

EC:2.7.11.23

GO:0008353

tr|T1FMV7|T1FMV7_HELRO
Uncharacterized protein
Search

0.50	D-amino-acid oxidase

0.76	GO:0046416	D-amino acid metabolic process
0.53	GO:0055114	oxidation-reduction process
0.34	GO:0006357	regulation of transcription by RNA polymerase II
0.33	GO:0042176	regulation of protein catabolic process
0.33	GO:0006351	transcription, DNA-templated
0.33	GO:0050790	regulation of catalytic activity

0.83	GO:0003884	D-amino-acid oxidase activity
0.73	GO:0071949	FAD binding
0.42	GO:0015922	aspartate oxidase activity
0.35	GO:0001104	RNA polymerase II transcription cofactor activity
0.33	GO:0030234	enzyme regulator activity

0.35	GO:0016592	mediator complex
0.33	GO:0031903	microbody membrane
0.33	GO:0044439	peroxisomal part
0.33	GO:1905369	endopeptidase complex
0.30	GO:0016021	integral component of membrane

0.83

EC:1.4.3.3

GO:0003884

tr|T1FMV8|T1FMV8_HELRO
Proteasome subunit alpha type
Search

0.51	Proteasome subunit alpha type

0.72	GO:0006511	ubiquitin-dependent protein catabolic process
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0010498	proteasomal protein catabolic process
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation
0.35	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia
0.35	GO:0070498	interleukin-1-mediated signaling pathway
0.35	GO:0038061	NIK/NF-kappaB signaling

0.77	GO:0004298	threonine-type endopeptidase activity
0.41	GO:0042802	identical protein binding
0.34	GO:0046982	protein heterodimerization activity
0.33	GO:0003743	translation initiation factor activity
0.33	GO:0003700	DNA binding transcription factor activity

0.79	GO:0019773	proteasome core complex, alpha-subunit complex
0.61	GO:0005634	nucleus
0.53	GO:1990111	spermatoproteasome complex
0.49	GO:0005737	cytoplasm
0.41	GO:0098794	postsynapse
0.36	GO:0070062	extracellular exosome
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part
0.34	GO:0000428	DNA-directed RNA polymerase complex
0.34	GO:0005667	transcription factor complex

0.77

EC:3.4.25

GO:0004298

tr|T1FMV9|T1FMV9_HELRO
Uncharacterized protein
Search

0.77	branched-chain-amino-acid aminotransferase-like protein 2

0.69

GO:0008483

transaminase activity

0.69

GO:0008483

tr|T1FMW0|T1FMW0_HELRO
Uncharacterized protein
Search

tr|T1FMW1|T1FMW1_HELRO
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Search

SDHB

0.69	Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial

0.70	GO:0006099	tricarboxylic acid cycle
0.60	GO:0022900	electron transport chain
0.34	GO:0006105	succinate metabolic process
0.34	GO:0007264	small GTPase mediated signal transduction
0.33	GO:0065009	regulation of molecular function

0.78	GO:0051538	3 iron, 4 sulfur cluster binding
0.77	GO:0008177	succinate dehydrogenase (ubiquinone) activity
0.70	GO:0051537	2 iron, 2 sulfur cluster binding
0.65	GO:0051539	4 iron, 4 sulfur cluster binding
0.61	GO:0009055	electron transfer activity
0.53	GO:0046872	metal ion binding
0.38	GO:0048039	ubiquinone binding
0.34	GO:0005515	protein binding
0.33	GO:0098772	molecular function regulator

0.55	GO:0031966	mitochondrial membrane
0.55	GO:0019866	organelle inner membrane
0.43	GO:0045257	succinate dehydrogenase complex (ubiquinone)
0.43	GO:0045283	fumarate reductase complex
0.40	GO:0098798	mitochondrial protein complex
0.39	GO:0005654	nucleoplasm
0.36	GO:0005886	plasma membrane
0.34	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.77	EC:1.3.5.1	GO:0008177
0.77	KEGG:R02164	GO:0008177

tr|T1FMW2|T1FMW2_HELRO
PRA1 family protein
Search

tr|T1FMW3|T1FMW3_HELRO
Uncharacterized protein
Search

ST13

0.88	Suppressor of tumorigenicity protein 13

0.42	GO:0061084	negative regulation of protein refolding
0.39	GO:0051289	protein homotetramerization
0.39	GO:0051085	chaperone cofactor-dependent protein refolding
0.35	GO:0046686	response to cadmium ion
0.33	GO:0006351	transcription, DNA-templated

0.66	GO:0046983	protein dimerization activity
0.41	GO:0032564	dATP binding
0.40	GO:0030544	Hsp70 protein binding
0.38	GO:0051087	chaperone binding
0.38	GO:0019904	protein domain specific binding
0.38	GO:0032403	protein complex binding
0.37	GO:0042802	identical protein binding
0.37	GO:0051082	unfolded protein binding
0.35	GO:0030674	protein binding, bridging
0.32	GO:0005524	ATP binding

0.42	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.35	GO:0043234	protein complex
0.33	GO:0005634	nucleus

tr|T1FMW4|T1FMW4_HELRO
Uncharacterized protein
Search

0.51	Ubiquitin-conjugating enzyme

0.74	GO:0000209	protein polyubiquitination
0.71	GO:0061057	peptidoglycan recognition protein signaling pathway
0.57	GO:0006301	postreplication repair
0.46	GO:0090325	regulation of locomotion involved in locomotory behavior
0.45	GO:2000008	regulation of protein localization to cell surface
0.42	GO:0008213	protein alkylation
0.41	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.41	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.40	GO:0043414	macromolecule methylation
0.39	GO:0009725	response to hormone

0.71	GO:0031624	ubiquitin conjugating enzyme binding
0.68	GO:0061631	ubiquitin conjugating enzyme activity
0.55	GO:0031625	ubiquitin protein ligase binding
0.53	GO:0061630	ubiquitin protein ligase activity
0.39	GO:0008168	methyltransferase activity
0.39	GO:0004930	G-protein coupled receptor activity
0.37	GO:0016874	ligase activity
0.35	GO:0003677	DNA binding

0.78	GO:0035370	UBC13-UEV1A complex
0.49	GO:0005634	nucleus
0.43	GO:0005829	cytosol
0.43	GO:0043005	neuron projection
0.39	GO:0000151	ubiquitin ligase complex
0.38	GO:0031974	membrane-enclosed lumen
0.36	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.39

GO:0008168

tr|T1FMW5|T1FMW5_HELRO
Amine oxidase
Search

0.38	Amine oxidase

0.53	GO:0055114	oxidation-reduction process
0.36	GO:0042402	cellular biogenic amine catabolic process
0.34	GO:0006357	regulation of transcription by RNA polymerase II

0.54	GO:0016491	oxidoreductase activity
0.34	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.34	GO:0008270	zinc ion binding

0.34	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0019866	organelle inner membrane
0.33	GO:0044444	cytoplasmic part
0.30	GO:0044425	membrane part

0.54

GO:0016491

tr|T1FMW6|T1FMW6_HELRO
Uncharacterized protein
Search

0.26

Aquaporin

0.55	GO:0055085	transmembrane transport
0.36	GO:0006833	water transport
0.32	GO:0006811	ion transport

0.69	GO:0015267	channel activity
0.36	GO:0005372	water transmembrane transporter activity

0.34	GO:0042807	central vacuole
0.34	GO:0009705	plant-type vacuole membrane
0.34	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

tr|T1FMW7|T1FMW7_HELRO
Uncharacterized protein
Search

0.82	6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase

0.83	GO:0006003	fructose 2,6-bisphosphate metabolic process
0.82	GO:0006000	fructose metabolic process
0.74	GO:0046835	carbohydrate phosphorylation
0.34	GO:0006757	ATP generation from ADP
0.34	GO:0006006	glucose metabolic process
0.34	GO:0006090	pyruvate metabolic process
0.34	GO:0016052	carbohydrate catabolic process
0.34	GO:0019362	pyridine nucleotide metabolic process
0.34	GO:0016311	dephosphorylation
0.33	GO:0006260	DNA replication

0.84	GO:0003873	6-phosphofructo-2-kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity
0.35	GO:0019901	protein kinase binding

0.35	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

0.84	EC:2.7.1.105	GO:0003873
0.84	KEGG:R02732	GO:0003873

tr|T1FMW8|T1FMW8_HELRO
Uncharacterized protein
Search

0.78	Gooseberry

0.70	GO:0007275	multicellular organism development
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.50	GO:0042060	wound healing
0.50	GO:2000288	positive regulation of myoblast proliferation
0.48	GO:0045595	regulation of cell differentiation
0.48	GO:0031062	positive regulation of histone methylation
0.47	GO:0031099	regeneration

0.64	GO:0043565	sequence-specific DNA binding
0.48	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding
0.41	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.40	GO:0001012	RNA polymerase II regulatory region DNA binding
0.39	GO:0003690	double-stranded DNA binding
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.34	GO:0005667	transcription factor complex

tr|T1FMW9|T1FMW9_HELRO
Uncharacterized protein
Search

0.71	SET and TTL domain-containing protein.9

0.60	GO:0036211	protein modification process
0.55	GO:0044267	cellular protein metabolic process
0.33	GO:0055114	oxidation-reduction process
0.33	GO:0051028	mRNA transport
0.33	GO:0008380	RNA splicing
0.32	GO:0006397	mRNA processing

0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0016874	ligase activity
0.39	GO:0008270	zinc ion binding
0.36	GO:0003676	nucleic acid binding
0.34	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.32	GO:0045735	nutrient reservoir activity
0.32	GO:0030145	manganese ion binding

0.39	GO:0005634	nucleus
0.32	GO:0031974	membrane-enclosed lumen
0.32	GO:0005576	extracellular region
0.32	GO:0044446	intracellular organelle part
0.31	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.49

GO:0016874

tr|T1FMX0|T1FMX0_HELRO
Uncharacterized protein
Search

0.40	GTP-binding protein YPT3

0.47	GO:0006887	exocytosis
0.47	GO:0032402	melanosome transport
0.45	GO:0060627	regulation of vesicle-mediated transport
0.44	GO:0046664	dorsal closure, amnioserosa morphology change
0.44	GO:0032482	Rab protein signal transduction
0.44	GO:0048210	Golgi vesicle fusion to target membrane
0.44	GO:0030723	ovarian fusome organization
0.44	GO:0007394	dorsal closure, elongation of leading edge cells
0.44	GO:0016197	endosomal transport
0.44	GO:0008103	oocyte microtubule cytoskeleton polarization

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.43	GO:0032794	GTPase activating protein binding
0.40	GO:0019003	GDP binding
0.40	GO:0031489	myosin V binding
0.40	GO:0032403	protein complex binding
0.39	GO:0045296	cadherin binding

0.49	GO:0055037	recycling endosome
0.44	GO:0070732	spindle envelope
0.44	GO:0060187	cell pole
0.43	GO:0045169	fusome
0.42	GO:0043195	terminal bouton
0.42	GO:0097610	cell surface furrow
0.42	GO:0005776	autophagosome
0.42	GO:0030140	trans-Golgi network transport vesicle
0.41	GO:0032155	cell division site part
0.41	GO:0048471	perinuclear region of cytoplasm

tr|T1FMX1|T1FMX1_HELRO
Uncharacterized protein
Search

0.62	GO:0021682	nerve maturation
0.60	GO:0060857	establishment of glial blood-brain barrier
0.60	GO:0019991	septate junction assembly
0.60	GO:0061343	cell adhesion involved in heart morphogenesis
0.57	GO:0008366	axon ensheathment
0.43	GO:0050767	regulation of neurogenesis
0.42	GO:0051961	negative regulation of nervous system development
0.42	GO:0010721	negative regulation of cell development
0.42	GO:0007411	axon guidance
0.40	GO:0055114	oxidation-reduction process

0.40	GO:0016491	oxidoreductase activity
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0004672	protein kinase activity
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0046872	metal ion binding
0.34	GO:0003676	nucleic acid binding

0.60	GO:0005918	septate junction
0.35	GO:0005576	extracellular region
0.33	GO:0005622	intracellular
0.30	GO:0016020	membrane

0.40

GO:0016491

tr|T1FMX2|T1FMX2_HELRO
Uncharacterized protein
Search

0.56	Kazal-type serine protease inhibitor domain-containing protein 1-like

0.73	GO:0001558	regulation of cell growth
0.61	GO:0006508	proteolysis

0.76	GO:0005520	insulin-like growth factor binding
0.61	GO:0008233	peptidase activity
0.57	GO:0017171	serine hydrolase activity

0.61

GO:0005576

extracellular region

0.61

GO:0008233

tr|T1FMX3|T1FMX3_HELRO
Uncharacterized protein
Search

0.57	Golgi phosphoprotein 3 rotini

0.45	GO:0007030	Golgi organization
0.45	GO:0007053	spindle assembly involved in male meiosis
0.45	GO:0007111	meiosis II cytokinesis
0.45	GO:0007110	meiosis I cytokinesis
0.45	GO:0036089	cleavage furrow formation
0.44	GO:0007112	male meiosis cytokinesis
0.44	GO:0000301	retrograde transport, vesicle recycling within Golgi
0.43	GO:0044837	actomyosin contractile ring organization
0.43	GO:0000912	assembly of actomyosin apparatus involved in cytokinesis
0.43	GO:0090307	mitotic spindle assembly

0.84	GO:0070273	phosphatidylinositol-4-phosphate binding
0.44	GO:0010314	phosphatidylinositol-5-phosphate binding
0.44	GO:0070300	phosphatidic acid binding
0.43	GO:0032266	phosphatidylinositol-3-phosphate binding
0.42	GO:0017137	Rab GTPase binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.43	GO:0097610	cell surface furrow
0.42	GO:0032155	cell division site part
0.42	GO:0005794	Golgi apparatus
0.38	GO:0098588	bounding membrane of organelle
0.38	GO:0005829	cytosol
0.37	GO:0031984	organelle subcompartment
0.34	GO:0031410	cytoplasmic vesicle

tr|T1FMX4|T1FMX4_HELRO
Glyceraldehyde-3-phosphate dehydrogenase
Search

0.50	Glyceraldehyde-3-phosphate dehydrogenase

0.68	GO:0006006	glucose metabolic process
0.64	GO:0006757	ATP generation from ADP
0.63	GO:0006090	pyruvate metabolic process
0.62	GO:0016052	carbohydrate catabolic process
0.61	GO:0019362	pyridine nucleotide metabolic process
0.52	GO:0055114	oxidation-reduction process

0.75	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
0.67	GO:0050661	NADP binding
0.65	GO:0051287	NAD binding

0.34

GO:0005737

cytoplasm

0.75

EC:1.2.1.12

GO:0004365

tr|T1FMX5|T1FMX5_HELRO
Uncharacterized protein
Search

NRBP1

0.93	Nuclear receptor binding protein 1

0.63	GO:0006468	protein phosphorylation
0.45	GO:0006888	ER to Golgi vesicle-mediated transport
0.42	GO:0036335	intestinal stem cell homeostasis
0.41	GO:0008361	regulation of cell size
0.40	GO:0042127	regulation of cell proliferation
0.39	GO:0035556	intracellular signal transduction
0.38	GO:0009306	protein secretion
0.34	GO:0006367	transcription initiation from RNA polymerase II promoter
0.33	GO:0033554	cellular response to stress

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0042803	protein homodimerization activity

0.43	GO:0012505	endomembrane system
0.43	GO:0005829	cytosol
0.38	GO:0005938	cell cortex
0.38	GO:0030027	lamellipodium
0.38	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0043231	intracellular membrane-bounded organelle
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

tr|T1FMX6|T1FMX6_HELRO
Uncharacterized protein
Search

0.75	ATPase family AAA domain-containing protein 1-B

0.43	GO:0010498	proteasomal protein catabolic process
0.42	GO:0019941	modification-dependent protein catabolic process
0.40	GO:0005975	carbohydrate metabolic process
0.39	GO:0006626	protein targeting to mitochondrion
0.35	GO:0051013	microtubule severing

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0004610	phosphoacetylglucosamine mutase activity
0.41	GO:0000287	magnesium ion binding
0.40	GO:0016887	ATPase activity
0.33	GO:0140096	catalytic activity, acting on a protein

0.46	GO:1905369	endopeptidase complex
0.41	GO:0043234	protein complex
0.40	GO:0005777	peroxisome
0.39	GO:0031903	microbody membrane
0.39	GO:0005741	mitochondrial outer membrane
0.36	GO:0005634	nucleus
0.36	GO:0045211	postsynaptic membrane
0.35	GO:0030054	cell junction
0.30	GO:0016021	integral component of membrane

0.48	EC:5.4.2.3	GO:0004610
0.48	KEGG:R08193	GO:0004610

tr|T1FMX7|T1FMX7_HELRO
Uncharacterized protein
Search

CLYBL

0.83	Citrate lyase beta like

0.57	GO:0106064	regulation of cobalamin metabolic process
0.54	GO:0070207	protein homotrimerization
0.35	GO:0006107	oxaloacetate metabolic process

0.57	GO:0047777	(3S)-citramalyl-CoA lyase activity
0.51	GO:0046872	metal ion binding
0.51	GO:0004474	malate synthase activity
0.35	GO:0008816	citryl-CoA lyase activity

0.43	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.57	EC:4.1.3.25	GO:0047777
0.57	KEGG:R00237	GO:0047777

tr|T1FMX8|T1FMX8_HELRO
Eukaryotic translation initiation factor 3 subunit G
Search

EIF3G

0.69	Eukaryotic translation initiation factor 3 subunit G-A

0.74	GO:0001731	formation of translation preinitiation complex
0.72	GO:0006446	regulation of translational initiation
0.53	GO:0075525	viral translational termination-reinitiation
0.34	GO:0002188	translation reinitiation
0.34	GO:0090116	C-5 methylation of cytosine
0.33	GO:0006415	translational termination
0.33	GO:0006508	proteolysis
0.32	GO:0007186	G-protein coupled receptor signaling pathway

0.73	GO:0003743	translation initiation factor activity
0.34	GO:0003886	DNA (cytosine-5-)-methyltransferase activity
0.34	GO:0005515	protein binding
0.34	GO:0003682	chromatin binding
0.33	GO:0004252	serine-type endopeptidase activity
0.33	GO:0008270	zinc ion binding
0.32	GO:0003677	DNA binding
0.32	GO:0004930	G-protein coupled receptor activity

0.78	GO:0005852	eukaryotic translation initiation factor 3 complex
0.73	GO:0016282	eukaryotic 43S preinitiation complex
0.73	GO:0033290	eukaryotic 48S preinitiation complex
0.55	GO:0048471	perinuclear region of cytoplasm
0.46	GO:0005634	nucleus
0.45	GO:0005829	cytosol
0.34	GO:0043614	multi-eIF complex
0.34	GO:0010494	cytoplasmic stress granule
0.30	GO:0016020	membrane

0.34

EC:2.1.1.37

GO:0003886

tr|T1FMX9|T1FMX9_HELRO
Serine/threonine-protein kinase PLK
Search

PLK1

0.82	Serine/threonine-protein kinase PLK

0.60	GO:0006468	protein phosphorylation
0.53	GO:0051081	nuclear envelope disassembly
0.52	GO:0070194	synaptonemal complex disassembly
0.52	GO:0090435	protein localization to nuclear envelope
0.52	GO:0072425	signal transduction involved in G2 DNA damage checkpoint
0.52	GO:0010800	positive regulation of peptidyl-threonine phosphorylation
0.52	GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity
0.52	GO:1901673	regulation of mitotic spindle assembly
0.52	GO:0071168	protein localization to chromatin
0.52	GO:0016321	female meiosis chromosome segregation

0.66	GO:0004674	protein serine/threonine kinase activity
0.52	GO:0030554	adenyl nucleotide binding
0.51	GO:0097367	carbohydrate derivative binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0008144	drug binding
0.50	GO:0010997	anaphase-promoting complex binding
0.48	GO:0019901	protein kinase binding
0.47	GO:0008017	microtubule binding
0.46	GO:0042802	identical protein binding
0.43	GO:0000287	magnesium ion binding

0.50	GO:0051233	spindle midzone
0.50	GO:0030496	midbody
0.50	GO:0000795	synaptonemal complex
0.49	GO:0005876	spindle microtubule
0.49	GO:0000942	condensed nuclear chromosome outer kinetochore
0.48	GO:0000922	spindle pole
0.48	GO:0005813	centrosome
0.45	GO:0000785	chromatin
0.30	GO:0016020	membrane

0.66

GO:0004674

tr|T1FMY0|T1FMY0_HELRO
Uncharacterized protein
Search

0.78	GO:0006888	ER to Golgi vesicle-mediated transport
0.41	GO:0006470	protein dephosphorylation
0.40	GO:0051301	cell division
0.40	GO:0006506	GPI anchor biosynthetic process
0.38	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.34	GO:0050790	regulation of catalytic activity
0.34	GO:0051246	regulation of protein metabolic process
0.34	GO:0044092	negative regulation of molecular function
0.34	GO:0051172	negative regulation of nitrogen compound metabolic process
0.34	GO:0031324	negative regulation of cellular metabolic process

0.50	GO:0016787	hydrolase activity
0.35	GO:0030234	enzyme regulator activity
0.34	GO:0046982	protein heterodimerization activity
0.33	GO:0003887	DNA-directed DNA polymerase activity
0.33	GO:0003677	DNA binding
0.33	GO:0003723	RNA binding
0.32	GO:0003735	structural constituent of ribosome

0.49	GO:0005737	cytoplasm
0.42	GO:0012505	endomembrane system
0.39	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0000786	nucleosome
0.33	GO:1905369	endopeptidase complex
0.32	GO:0043234	protein complex
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016020	membrane

0.50

GO:0016787

tr|T1FMY1|T1FMY1_HELRO
Uncharacterized protein
Search

CTH

0.55	Cystathionine gamma-lyase inhibitor

0.53	GO:0019346	transsulfuration
0.51	GO:0019343	cysteine biosynthetic process via cystathionine
0.51	GO:0044524	protein sulfhydration
0.50	GO:0018272	protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine
0.50	GO:1904831	positive regulation of aortic smooth muscle cell differentiation
0.47	GO:0051289	protein homotetramerization
0.46	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.46	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.46	GO:1990823	response to leukemia inhibitory factor
0.46	GO:2001234	negative regulation of apoptotic signaling pathway

0.67	GO:0030170	pyridoxal phosphate binding
0.55	GO:0016829	lyase activity
0.46	GO:0003962	cystathionine gamma-synthase activity
0.43	GO:0042802	identical protein binding
0.35	GO:0005516	calmodulin binding

0.36	GO:0005737	cytoplasm
0.34	GO:0070062	extracellular exosome
0.33	GO:0012505	endomembrane system
0.32	GO:0043231	intracellular membrane-bounded organelle

0.55

EC:4

GO:0016829

tr|T1FMY2|T1FMY2_HELRO
Uncharacterized protein
Search

PLBD2

0.79	Phospholipase B-like

0.72	GO:0016042	lipid catabolic process
0.34	GO:0000281	mitotic cytokinesis
0.33	GO:0006468	protein phosphorylation

0.51	GO:0016787	hydrolase activity
0.33	GO:0004674	protein serine/threonine kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.39	GO:0005764	lysosome
0.30	GO:0031224	intrinsic component of membrane

0.51

GO:0016787

tr|T1FMY3|T1FMY3_HELRO
Uncharacterized protein
Search

TSTA3

0.50	GDP-L-fucose synthetase

0.74	GO:0009226	nucleotide-sugar biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.52	GO:0046368	GDP-L-fucose metabolic process
0.50	GO:0019673	GDP-mannose metabolic process
0.50	GO:0019835	cytolysis
0.35	GO:0007159	leukocyte cell-cell adhesion
0.33	GO:0006413	translational initiation
0.33	GO:0006091	generation of precursor metabolites and energy

0.60	GO:0050662	coenzyme binding
0.54	GO:0016491	oxidoreductase activity
0.48	GO:0042802	identical protein binding
0.35	GO:0016853	isomerase activity
0.33	GO:0003743	translation initiation factor activity

0.36	GO:0070062	extracellular exosome
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.54

GO:0016491

tr|T1FMY4|T1FMY4_HELRO
Uncharacterized protein
Search

0.36	RNA binding protein Gbfne

0.48	GO:0036093	germ cell proliferation
0.47	GO:0060856	establishment of blood-brain barrier
0.45	GO:0048477	oogenesis
0.39	GO:0009653	anatomical structure morphogenesis
0.39	GO:0007399	nervous system development
0.38	GO:0007612	learning
0.38	GO:0016358	dendrite development
0.38	GO:0007626	locomotory behavior
0.37	GO:0120036	plasma membrane bounded cell projection organization
0.36	GO:0000381	regulation of alternative mRNA splicing, via spliceosome

0.59

GO:0003723

RNA binding

0.37	GO:0005634	nucleus
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

tr|T1FMY5|T1FMY5_HELRO
Uncharacterized protein
Search

PDSS1

0.93	Decaprenyl diphosphate synthase subunit 1

0.71	GO:0008299	isoprenoid biosynthetic process
0.54	GO:0051290	protein heterotetramerization
0.49	GO:0006744	ubiquinone biosynthetic process
0.33	GO:0006508	proteolysis

0.56	GO:0000010	trans-hexaprenyltranstransferase activity
0.54	GO:0050347	trans-octaprenyltranstransferase activity
0.48	GO:0046982	protein heterodimerization activity
0.34	GO:0036422	heptaprenyl diphosphate synthase activity
0.34	GO:0046872	metal ion binding
0.33	GO:0008237	metallopeptidase activity

0.46	GO:1990234	transferase complex
0.42	GO:0005739	mitochondrion
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0044446	intracellular organelle part

0.54	EC:2.5.1.84 EC:2.5.1.85	GO:0050347
0.56	KEGG:R05612	GO:0000010

tr|T1FMY6|T1FMY6_HELRO
Uncharacterized protein
Search

U2AF2

0.72	U2 snRNP auxiliary factor large subunit

0.73	GO:0008380	RNA splicing
0.69	GO:0006397	mRNA processing
0.47	GO:0048025	negative regulation of mRNA splicing, via spliceosome
0.46	GO:0033120	positive regulation of RNA splicing
0.46	GO:1903146	regulation of autophagy of mitochondrion
0.46	GO:1903955	positive regulation of protein targeting to mitochondrion
0.46	GO:0031397	negative regulation of protein ubiquitination
0.44	GO:0046660	female sex differentiation

0.59	GO:0003723	RNA binding
0.47	GO:0070742	C2H2 zinc finger domain binding
0.42	GO:0019899	enzyme binding

0.61	GO:0005634	nucleus
0.46	GO:0000974	Prp19 complex
0.43	GO:0031974	membrane-enclosed lumen
0.42	GO:0030529	intracellular ribonucleoprotein complex
0.40	GO:0044446	intracellular organelle part
0.37	GO:0019013	viral nucleocapsid

tr|T1FMY7|T1FMY7_HELRO
Uncharacterized protein
Search

tr|T1FMY8|T1FMY8_HELRO
Uncharacterized protein
Search

SIRT6

0.61	NAD-dependent protein deacetylase sirtuin-6

0.53	GO:0031937	positive regulation of chromatin silencing
0.51	GO:1905547	regulation of telomeric heterochromatin assembly
0.51	GO:1905555	positive regulation blood vessel branching
0.50	GO:1902732	positive regulation of chondrocyte proliferation
0.50	GO:1990619	histone H3-K9 deacetylation
0.50	GO:1905564	positive regulation of vascular endothelial cell proliferation
0.50	GO:0031453	positive regulation of heterochromatin assembly
0.49	GO:0061647	histone H3-K9 modification
0.49	GO:0010569	regulation of double-strand break repair via homologous recombination
0.48	GO:0031938	regulation of chromatin silencing at telomere

0.77	GO:0070403	NAD+ binding
0.51	GO:0046969	NAD-dependent histone deacetylase activity (H3-K9 specific)
0.45	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity
0.43	GO:0003714	transcription corepressor activity
0.42	GO:0003682	chromatin binding
0.34	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.34	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding
0.34	GO:0004725	protein tyrosine phosphatase activity

0.49	GO:0005724	nuclear telomeric heterochromatin
0.43	GO:0005654	nucleoplasm
0.36	GO:0005730	nucleolus
0.33	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.45

EC:2.4.2.31

GO:0003956

tr|T1FMY9|T1FMY9_HELRO
Uncharacterized protein
Search

MBD2

0.88	LOW QUALITY PROTEIN: methyl-CpG-binding domain protein 2

0.54	GO:0006346	methylation-dependent chromatin silencing
0.50	GO:0042711	maternal behavior
0.49	GO:0000122	negative regulation of transcription by RNA polymerase II
0.48	GO:0030177	positive regulation of Wnt signaling pathway
0.45	GO:0042127	regulation of cell proliferation
0.44	GO:0043623	cellular protein complex assembly
0.40	GO:0030261	chromosome condensation
0.36	GO:0007275	multicellular organism development
0.35	GO:0035563	positive regulation of chromatin binding
0.35	GO:0044030	regulation of DNA methylation

0.56	GO:0008327	methyl-CpG binding
0.50	GO:0070742	C2H2 zinc finger domain binding
0.49	GO:0035197	siRNA binding
0.45	GO:0003682	chromatin binding
0.45	GO:0003729	mRNA binding
0.42	GO:0042826	histone deacetylase binding
0.41	GO:0003714	transcription corepressor activity
0.40	GO:0042803	protein homodimerization activity
0.35	GO:0003696	satellite DNA binding
0.35	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding

0.60	GO:0005634	nucleus
0.47	GO:0000792	heterochromatin
0.45	GO:0031974	membrane-enclosed lumen
0.43	GO:0005829	cytosol
0.42	GO:1902494	catalytic complex
0.42	GO:0005700	polytene chromosome
0.41	GO:0017053	transcriptional repressor complex
0.33	GO:0043234	protein complex

tr|T1FMZ0|T1FMZ0_HELRO
Uncharacterized protein
Search

ARF6

0.65	ADP-ribosylation factor

0.54	GO:0035020	regulation of Rac protein signal transduction
0.54	GO:0001889	liver development
0.54	GO:0036010	protein localization to endosome
0.54	GO:0033028	myeloid cell apoptotic process
0.54	GO:0097178	ruffle assembly
0.53	GO:0097284	hepatocyte apoptotic process
0.53	GO:0051489	regulation of filopodium assembly
0.52	GO:0032456	endocytic recycling
0.52	GO:0034394	protein localization to cell surface
0.52	GO:1903078	positive regulation of protein localization to plasma membrane

0.66	GO:0005525	GTP binding
0.55	GO:0031996	thioesterase binding
0.51	GO:0047485	protein N-terminus binding
0.35	GO:0003924	GTPase activity
0.35	GO:0031681	G-protein beta-subunit binding
0.33	GO:0031683	G-protein beta/gamma-subunit complex binding
0.32	GO:0004871	signal transducer activity

0.54	GO:0031527	filopodium membrane
0.54	GO:0090543	Flemming body
0.54	GO:0055038	recycling endosome membrane
0.53	GO:0032154	cleavage furrow
0.52	GO:0001726	ruffle
0.51	GO:0030139	endocytic vesicle
0.50	GO:0043209	myelin sheath
0.49	GO:0005938	cell cortex
0.37	GO:0005769	early endosome
0.37	GO:0005829	cytosol

tr|T1FMZ1|T1FMZ1_HELRO
Uncharacterized protein
Search

0.61	ADP-ribosylation factor

0.46	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.44	GO:1990386	mitotic cleavage furrow ingression
0.42	GO:1904748	regulation of apoptotic process involved in development
0.41	GO:0098586	cellular response to virus
0.41	GO:0048259	regulation of receptor-mediated endocytosis
0.41	GO:0048599	oocyte development
0.41	GO:0006878	cellular copper ion homeostasis
0.40	GO:0009792	embryo development ending in birth or egg hatching
0.39	GO:0015031	protein transport
0.39	GO:0007005	mitochondrion organization

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0019904	protein domain specific binding
0.39	GO:0046982	protein heterodimerization activity
0.37	GO:0000287	magnesium ion binding
0.33	GO:0005102	receptor binding
0.33	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.33	GO:0003924	GTPase activity

0.47	GO:0005794	Golgi apparatus
0.41	GO:0030017	sarcomere
0.41	GO:0031252	cell leading edge
0.38	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0005829	cytosol
0.38	GO:0005783	endoplasmic reticulum
0.36	GO:0043234	protein complex
0.36	GO:0031982	vesicle
0.36	GO:0043230	extracellular organelle
0.35	GO:0005615	extracellular space

0.33

GO:0003755

tr|T1FMZ2|T1FMZ2_HELRO
Uncharacterized protein
Search

tr|T1FMZ3|T1FMZ3_HELRO
Uncharacterized protein
Search

0.85	neuron-specific calcium-binding protein hippocalcin

0.52	GO:1901385	regulation of voltage-gated calcium channel activity
0.52	GO:0071277	cellular response to calcium ion
0.50	GO:0048839	inner ear development
0.43	GO:0048841	regulation of axon extension involved in axon guidance
0.40	GO:0019722	calcium-mediated signaling
0.39	GO:1904010	response to Aroclor 1254
0.39	GO:1901986	response to ketamine
0.39	GO:1904009	cellular response to monosodium glutamate
0.38	GO:0010562	positive regulation of phosphorus metabolic process
0.38	GO:0060341	regulation of cellular localization

0.70	GO:0005509	calcium ion binding
0.47	GO:0042802	identical protein binding
0.47	GO:0003779	actin binding
0.38	GO:0098744	1-phosphatidylinositol 4-kinase activator activity
0.36	GO:0019900	kinase binding
0.34	GO:0004843	thiol-dependent ubiquitin-specific protease activity

0.38	GO:0044327	dendritic spine head
0.38	GO:0005737	cytoplasm
0.37	GO:0032809	neuronal cell body membrane
0.37	GO:0032590	dendrite membrane
0.37	GO:0019898	extrinsic component of membrane
0.37	GO:0043204	perikaryon
0.36	GO:0030424	axon
0.35	GO:0070062	extracellular exosome
0.34	GO:0098588	bounding membrane of organelle
0.34	GO:0031984	organelle subcompartment

tr|T1FMZ4|T1FMZ4_HELRO
Uncharacterized protein
Search

UBE2R2

0.88	Ubiquitin-conjugating enzyme E2R 2

0.47	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.45	GO:0016567	protein ubiquitination

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0031625	ubiquitin protein ligase binding
0.46	GO:0061630	ubiquitin protein ligase activity

0.37

GO:0005737

cytoplasm

tr|T1FMZ5|T1FMZ5_HELRO
Uncharacterized protein
Search

tr|T1FMZ6|T1FMZ6_HELRO
Uncharacterized protein
Search

0.86	GO:1900186	negative regulation of clathrin-dependent endocytosis
0.86	GO:1904021	negative regulation of G-protein coupled receptor internalization
0.85	GO:1903071	positive regulation of ER-associated ubiquitin-dependent protein catabolic process
0.82	GO:2000785	regulation of autophagosome assembly
0.78	GO:0030433	ubiquitin-dependent ERAD pathway
0.54	GO:0042982	amyloid precursor protein metabolic process
0.44	GO:0006914	autophagy

0.52

GO:0070628

proteasome binding

0.65	GO:0005829	cytosol
0.53	GO:0005886	plasma membrane
0.45	GO:0005776	autophagosome
0.42	GO:0031410	cytoplasmic vesicle
0.39	GO:0005634	nucleus

tr|T1FMZ7|T1FMZ7_HELRO
V-type proton ATPase proteolipid subunit
Search

0.61	V-type proton ATPase proteolipid subunit

0.76	GO:0015991	ATP hydrolysis coupled proton transport
0.50	GO:0007033	vacuole organization
0.47	GO:0007035	vacuolar acidification
0.44	GO:0030177	positive regulation of Wnt signaling pathway
0.43	GO:0006623	protein targeting to vacuole
0.42	GO:0006878	cellular copper ion homeostasis
0.41	GO:0006879	cellular iron ion homeostasis
0.40	GO:0060035	notochord cell development
0.40	GO:0006897	endocytosis
0.40	GO:0001878	response to yeast

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.45	GO:0036442	proton-exporting ATPase activity
0.43	GO:0031625	ubiquitin protein ligase binding
0.43	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
0.34	GO:0008448	N-acetylglucosamine-6-phosphate deacetylase activity

0.78	GO:0033179	proton-transporting V-type ATPase, V0 domain
0.76	GO:0005774	vacuolar membrane
0.35	GO:0101003	ficolin-1-rich granule membrane
0.35	GO:0070821	tertiary granule membrane
0.35	GO:0005766	primary lysosome
0.35	GO:0030670	phagocytic vesicle membrane
0.34	GO:0005925	focal adhesion
0.34	GO:0070062	extracellular exosome
0.34	GO:0010008	endosome membrane
0.32	GO:0005886	plasma membrane

0.34

EC:3.5.1.25

GO:0008448

tr|T1FMZ8|T1FMZ8_HELRO
Adenosylhomocysteinase
Search

AHCY

0.55	Adenosylhomocysteinase A

0.79	GO:0019510	S-adenosylhomocysteine catabolic process
0.72	GO:0006730	one-carbon metabolic process
0.45	GO:0033353	S-adenosylmethionine cycle
0.35	GO:0002439	chronic inflammatory response to antigenic stimulus
0.35	GO:0042745	circadian sleep/wake cycle
0.34	GO:0071268	homocysteine biosynthetic process
0.34	GO:0001666	response to hypoxia
0.34	GO:0007584	response to nutrient
0.33	GO:0032259	methylation

0.80	GO:0004013	adenosylhomocysteinase activity
0.66	GO:0051287	NAD binding
0.34	GO:0042802	identical protein binding
0.32	GO:0030554	adenyl nucleotide binding

0.44	GO:0005829	cytosol
0.37	GO:0042470	melanosome
0.34	GO:0070062	extracellular exosome
0.34	GO:0043005	neuron projection
0.33	GO:0005634	nucleus

0.80

EC:3.3.1.1

GO:0004013

tr|T1FMZ9|T1FMZ9_HELRO
Transgelin
Search

0.64	Transgelin

0.77	GO:0035626	juvenile hormone mediated signaling pathway
0.62	GO:0031032	actomyosin structure organization
0.47	GO:0006939	smooth muscle contraction
0.41	GO:1901739	regulation of myoblast fusion
0.41	GO:0007520	myoblast fusion

0.79	GO:0070594	juvenile hormone response element binding
0.60	GO:0005516	calmodulin binding
0.60	GO:0003779	actin binding

0.46	GO:0005865	striated muscle thin filament
0.30	GO:0031224	intrinsic component of membrane

tr|T1FN00|T1FN00_HELRO
Uncharacterized protein
Search

RCAN2

0.84	Down syndrome critical region gene 1

0.84	GO:0019722	calcium-mediated signaling
0.53	GO:0048016	inositol phosphate-mediated signaling
0.47	GO:0070884	regulation of calcineurin-NFAT signaling cascade
0.44	GO:0043666	regulation of phosphoprotein phosphatase activity
0.40	GO:0031987	locomotion involved in locomotory behavior
0.39	GO:0007614	short-term memory
0.38	GO:0007219	Notch signaling pathway
0.37	GO:0006979	response to oxidative stress
0.36	GO:0002040	sprouting angiogenesis

0.51	GO:0003676	nucleic acid binding
0.48	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity

0.45	GO:0005622	intracellular
0.30	GO:0016020	membrane

tr|T1FN01|T1FN01_HELRO
ATP synthase subunit beta
Search

0.43	ATP synthase subunit beta

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.69	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.35	GO:0016477	cell migration
0.35	GO:0043050	pharyngeal pumping
0.35	GO:0030421	defecation
0.35	GO:0040024	dauer larval development
0.35	GO:0007617	mating behavior
0.34	GO:0008340	determination of adult lifespan
0.34	GO:0050829	defense response to Gram-negative bacterium

0.72	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005509	calcium ion binding
0.34	GO:0016758	transferase activity, transferring hexosyl groups
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0032561	guanyl ribonucleotide binding
0.34	GO:0019904	protein domain specific binding

0.72	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)
0.35	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0097730	non-motile cilium
0.34	GO:0005739	mitochondrion
0.34	GO:0043209	myelin sheath
0.34	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.34

EC:2.4.1

GO:0016758

tr|T1FN02|T1FN02_HELRO
Uncharacterized protein
Search

0.63	GO:0006457	protein folding
0.50	GO:0032781	positive regulation of ATPase activity
0.48	GO:0030433	ubiquitin-dependent ERAD pathway
0.47	GO:0045454	cell redox homeostasis
0.45	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
0.42	GO:0009408	response to heat
0.42	GO:0001933	negative regulation of protein phosphorylation
0.39	GO:0055114	oxidation-reduction process
0.39	GO:0006260	DNA replication
0.39	GO:0060715	syncytiotrophoblast cell differentiation involved in labyrinthine layer development

0.61	GO:0051082	unfolded protein binding
0.50	GO:0001671	ATPase activator activity
0.49	GO:0051087	chaperone binding
0.48	GO:0031072	heat shock protein binding
0.46	GO:0015036	disulfide oxidoreductase activity
0.45	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
0.45	GO:0051787	misfolded protein binding
0.45	GO:0051117	ATPase binding
0.39	GO:0008270	zinc ion binding
0.38	GO:0003676	nucleic acid binding

0.48	GO:0005788	endoplasmic reticulum lumen
0.46	GO:0034663	endoplasmic reticulum chaperone complex
0.42	GO:0005829	cytosol
0.42	GO:0005654	nucleoplasm
0.38	GO:0005886	plasma membrane
0.35	GO:0030018	Z disc
0.34	GO:0070062	extracellular exosome
0.34	GO:0048471	perinuclear region of cytoplasm
0.30	GO:0016021	integral component of membrane

0.45

EC:1.8.4

GO:0016671

tr|T1FN03|T1FN03_HELRO
Uncharacterized protein
Search

COX7C

0.81	Cytochrome oxidase subunit VIIc

0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0022900	electron transport chain
0.42	GO:0006119	oxidative phosphorylation
0.42	GO:0009060	aerobic respiration

0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity

0.50	GO:0005751	mitochondrial respiratory chain complex IV
0.30	GO:0016021	integral component of membrane

0.65

EC:1.9.3

GO:0016676

tr|T1FN04|T1FN04_HELRO
Uncharacterized protein
Search

tr|T1FN05|T1FN05_HELRO
Uncharacterized protein
Search

tr|T1FN06|T1FN06_HELRO
Uncharacterized protein
Search

0.84	Cell cycle control protein 50A

0.50	GO:0015914	phospholipid transport
0.49	GO:0070863	positive regulation of protein exit from endoplasmic reticulum
0.40	GO:0071705	nitrogen compound transport
0.37	GO:0036010	protein localization to endosome
0.36	GO:0010976	positive regulation of neuron projection development
0.36	GO:0034204	lipid translocation
0.35	GO:0006855	drug transmembrane transport

0.50	GO:0015247	aminophospholipid transmembrane transporter activity
0.34	GO:0008483	transaminase activity
0.34	GO:0030170	pyridoxal phosphate binding
0.33	GO:0005515	protein binding
0.32	GO:0003677	DNA binding

0.35	GO:0012505	endomembrane system
0.35	GO:0005886	plasma membrane
0.34	GO:0045177	apical part of cell
0.34	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0030659	cytoplasmic vesicle membrane
0.34	GO:0098805	whole membrane
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0000786	nucleosome
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0008483

tr|T1FN07|T1FN07_HELRO
Uncharacterized protein
Search

ACMSD

0.42	Aminocarboxymuconate semialdehyde decarboxylase

0.43	GO:1904984	regulation of quinolinate biosynthetic process
0.38	GO:0009890	negative regulation of biosynthetic process
0.38	GO:0051259	protein oligomerization
0.38	GO:0051172	negative regulation of nitrogen compound metabolic process
0.38	GO:0031324	negative regulation of cellular metabolic process
0.35	GO:0046874	quinolinate metabolic process
0.35	GO:0006769	nicotinamide metabolic process
0.34	GO:0006568	tryptophan metabolic process
0.33	GO:0006468	protein phosphorylation
0.32	GO:0055114	oxidation-reduction process

0.68	GO:0016831	carboxy-lyase activity
0.51	GO:0016787	hydrolase activity
0.36	GO:0008270	zinc ion binding
0.34	GO:0000334	3-hydroxyanthranilate 3,4-dioxygenase activity
0.33	GO:0004672	protein kinase activity
0.33	GO:0005506	iron ion binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.40	GO:0005829	cytosol
0.34	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.68	EC:4.1.1	GO:0016831
0.34	KEGG:R02665	GO:0000334

tr|T1FN08|T1FN08_HELRO
Uncharacterized protein
Search

OSTF1

0.56	Osteoclast-stimulating factor

0.40	GO:0043312	neutrophil degranulation
0.39	GO:0001503	ossification
0.35	GO:0007165	signal transduction

0.76

GO:0017124

SH3 domain binding

0.65	GO:0005576	extracellular region
0.41	GO:1904813	ficolin-1-rich granule lumen
0.40	GO:0034774	secretory granule lumen
0.30	GO:0044425	membrane part

tr|T1FN09|T1FN09_HELRO
Uncharacterized protein
Search

PPIL2

0.81	Peptidyl-prolyl cis-trans isomerase 2

0.72	GO:0016567	protein ubiquitination
0.72	GO:0000413	protein peptidyl-prolyl isomerization
0.68	GO:0006457	protein folding
0.48	GO:0072659	protein localization to plasma membrane
0.37	GO:0040022	feminization of hermaphroditic germ-line
0.34	GO:0050900	leukocyte migration
0.33	GO:0000723	telomere maintenance
0.33	GO:0006508	proteolysis
0.32	GO:0032392	DNA geometric change
0.32	GO:0006310	DNA recombination

0.73	GO:0004842	ubiquitin-protein transferase activity
0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.48	GO:0061659	ubiquitin-like protein ligase activity
0.34	GO:0004197	cysteine-type endopeptidase activity
0.33	GO:0005515	protein binding
0.32	GO:0003678	DNA helicase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.44	GO:0005654	nucleoplasm
0.39	GO:0005886	plasma membrane
0.37	GO:0005737	cytoplasm
0.33	GO:0012505	endomembrane system
0.30	GO:0031224	intrinsic component of membrane

0.72	EC:5.2.1.8	GO:0003755
0.73	KEGG:R03876	GO:0004842

tr|T1FN10|T1FN10_HELRO
Uncharacterized protein
Search

0.92	Misexpression suppressor of KSR

0.69	GO:0046579	positive regulation of Ras protein signal transduction
0.66	GO:0032287	peripheral nervous system myelin maintenance
0.65	GO:0045576	mast cell activation
0.58	GO:0042127	regulation of cell proliferation
0.44	GO:0090232	positive regulation of spindle checkpoint
0.43	GO:0030330	DNA damage response, signal transduction by p53 class mediator
0.43	GO:0071456	cellular response to hypoxia
0.39	GO:0048523	negative regulation of cellular process

0.42	GO:0043015	gamma-tubulin binding
0.42	GO:0045296	cadherin binding
0.42	GO:0017137	Rab GTPase binding
0.40	GO:0008017	microtubule binding

0.43	GO:0055038	recycling endosome membrane
0.42	GO:0005913	cell-cell adherens junction
0.42	GO:0043209	myelin sheath
0.41	GO:0048471	perinuclear region of cytoplasm
0.41	GO:0005813	centrosome
0.40	GO:0005874	microtubule
0.39	GO:0005829	cytosol
0.37	GO:0005634	nucleus
0.36	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|T1FN11|T1FN11_HELRO
Uncharacterized protein
Search

SMARCB1

0.89	Integrase interactor

0.78	GO:0006338	chromatin remodeling
0.50	GO:0008285	negative regulation of cell proliferation
0.48	GO:0001835	blastocyst hatching
0.47	GO:0030154	cell differentiation
0.44	GO:0043697	cell dedifferentiation
0.44	GO:0008586	imaginal disc-derived wing vein morphogenesis
0.44	GO:0007474	imaginal disc-derived wing vein specification
0.44	GO:0008587	imaginal disc-derived wing margin morphogenesis
0.44	GO:0031498	chromatin disassembly
0.44	GO:0032986	protein-DNA complex disassembly

0.46	GO:0030957	Tat protein binding
0.45	GO:0070984	SET domain binding
0.36	GO:0001164	RNA polymerase I CORE element sequence-specific DNA binding
0.36	GO:0002039	p53 binding
0.35	GO:0003713	transcription coactivator activity
0.34	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.34	GO:0031492	nucleosomal DNA binding
0.34	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.33	GO:0004222	metalloendopeptidase activity
0.33	GO:0008270	zinc ion binding

0.73	GO:0000228	nuclear chromosome
0.47	GO:0001741	XY body
0.47	GO:0001650	fibrillar center
0.46	GO:0000785	chromatin
0.44	GO:0097458	neuron part
0.44	GO:1904949	ATPase complex
0.43	GO:0005654	nucleoplasm
0.33	GO:0031012	extracellular matrix
0.33	GO:0043234	protein complex

0.33

GO:0004222

tr|T1FN12|T1FN12_HELRO
Uncharacterized protein
Search

tr|T1FN13|T1FN13_HELRO
Uncharacterized protein
Search

0.72	ER membrane protein complex subunit 3

0.46	GO:0001654	eye development
0.44	GO:0016063	rhodopsin biosynthetic process
0.43	GO:0034975	protein folding in endoplasmic reticulum
0.43	GO:0045494	photoreceptor cell maintenance
0.43	GO:0042461	photoreceptor cell development
0.42	GO:0090596	sensory organ morphogenesis
0.42	GO:0042060	wound healing
0.38	GO:0006996	organelle organization

0.32

GO:0016787

hydrolase activity

0.44	GO:0012505	endomembrane system
0.42	GO:0030136	clathrin-coated vesicle
0.41	GO:0005798	Golgi-associated vesicle
0.40	GO:0043231	intracellular membrane-bounded organelle
0.39	GO:0031984	organelle subcompartment
0.38	GO:0098796	membrane protein complex
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016787

tr|T1FN14|T1FN14_HELRO
Uncharacterized protein
Search

RBBP5

0.80	Retinoblastoma-binding protein 5

0.39	GO:0051568	histone H3-K4 methylation
0.38	GO:0043627	response to estrogen
0.37	GO:1904837	beta-catenin-TCF complex assembly
0.36	GO:0045652	regulation of megakaryocyte differentiation
0.35	GO:0043687	post-translational protein modification
0.35	GO:0006974	cellular response to DNA damage stimulus
0.33	GO:0006351	transcription, DNA-templated
0.33	GO:2001141	regulation of RNA biosynthetic process
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.38	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.38	GO:0140034	methylation-dependent protein binding
0.37	GO:0042393	histone binding
0.37	GO:0044212	transcription regulatory region DNA binding

0.79	GO:0048188	Set1C/COMPASS complex
0.38	GO:0044666	MLL3/4 complex
0.38	GO:0005730	nucleolus
0.38	GO:0071339	MLL1 complex
0.30	GO:0016020	membrane

tr|T1FN15|T1FN15_HELRO
Uncharacterized protein
Search

CYC1

0.32	Cytochrome component of the mitochondrialrespiratory chain

0.61	GO:0022900	electron transport chain
0.42	GO:0006119	oxidative phosphorylation
0.41	GO:0045333	cellular respiration
0.39	GO:0042776	mitochondrial ATP synthesis coupled proton transport

0.63	GO:0020037	heme binding
0.62	GO:0009055	electron transfer activity
0.53	GO:0046872	metal ion binding
0.35	GO:0016681	oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor

0.49	GO:0005750	mitochondrial respiratory chain complex III
0.34	GO:0042765	GPI-anchor transamidase complex
0.34	GO:0005758	mitochondrial intermembrane space
0.33	GO:0005829	cytosol

0.35

EC:1.10.2

GO:0016681

tr|T1FN16|T1FN16_HELRO
Uncharacterized protein
Search

CHMP2A

0.64	Charged multivesicular body protein 2a

0.79	GO:0007034	vacuolar transport
0.50	GO:1903723	negative regulation of centriole elongation
0.50	GO:0010458	exit from mitosis
0.50	GO:0031468	nuclear envelope reassembly
0.49	GO:1903543	positive regulation of exosomal secretion
0.48	GO:1902188	positive regulation of viral release from host cell
0.48	GO:1901673	regulation of mitotic spindle assembly
0.47	GO:0000920	cell separation after cytokinesis
0.47	GO:0051291	protein heterooligomerization
0.47	GO:0010324	membrane invagination

0.48	GO:0031210	phosphatidylcholine binding
0.44	GO:0019904	protein domain specific binding
0.33	GO:0008168	methyltransferase activity

0.48	GO:0000815	ESCRT III complex
0.46	GO:0005635	nuclear envelope
0.44	GO:0048475	coated membrane
0.43	GO:0000785	chromatin
0.41	GO:0005829	cytosol
0.40	GO:0005770	late endosome
0.34	GO:0070062	extracellular exosome
0.34	GO:0005769	early endosome
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0008168

tr|T1FN17|T1FN17_HELRO
Uncharacterized protein
Search

0.30	Fibrinolytic enzyme

0.61	GO:0006508	proteolysis
0.41	GO:0006030	chitin metabolic process
0.40	GO:0007596	blood coagulation
0.37	GO:0042730	fibrinolysis
0.36	GO:0016310	phosphorylation
0.35	GO:0007313	maternal specification of dorsal/ventral axis, oocyte, soma encoded
0.34	GO:0005975	carbohydrate metabolic process
0.34	GO:0007306	eggshell chorion assembly

0.69	GO:0004252	serine-type endopeptidase activity
0.41	GO:0008061	chitin binding
0.36	GO:0016301	kinase activity
0.36	GO:0005509	calcium ion binding
0.36	GO:0030246	carbohydrate binding
0.35	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.40	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.69

GO:0004252

tr|T1FN18|T1FN18_HELRO
Uncharacterized protein
Search

0.94	Fibrinolytic enzyme

0.61	GO:0006508	proteolysis
0.43	GO:0016310	phosphorylation
0.39	GO:0042730	fibrinolysis
0.38	GO:0007596	blood coagulation
0.36	GO:0006898	receptor-mediated endocytosis
0.34	GO:0007186	G-protein coupled receptor signaling pathway

0.69	GO:0004252	serine-type endopeptidase activity
0.44	GO:0016301	kinase activity
0.37	GO:0005044	scavenger receptor activity
0.34	GO:0004930	G-protein coupled receptor activity

0.36	GO:0046658	anchored component of plasma membrane
0.35	GO:0019897	extrinsic component of plasma membrane
0.30	GO:0016021	integral component of membrane

0.69

GO:0004252

tr|T1FN19|T1FN19_HELRO
Uncharacterized protein
Search

0.65	Fibrinolytic enzyme

0.61	GO:0006508	proteolysis
0.39	GO:0016310	phosphorylation
0.38	GO:0005975	carbohydrate metabolic process
0.38	GO:0060309	elastin catabolic process
0.38	GO:0006950	response to stress
0.38	GO:0032501	multicellular organismal process
0.37	GO:0051239	regulation of multicellular organismal process
0.37	GO:0007599	hemostasis
0.36	GO:1900047	negative regulation of hemostasis
0.36	GO:0048589	developmental growth

0.69	GO:0004252	serine-type endopeptidase activity
0.41	GO:0030246	carbohydrate binding
0.40	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.40	GO:0016301	kinase activity
0.37	GO:0005509	calcium ion binding
0.36	GO:0005044	scavenger receptor activity
0.35	GO:0001855	complement component C4b binding
0.34	GO:0048306	calcium-dependent protein binding
0.33	GO:0004435	phosphatidylinositol phospholipase C activity
0.33	GO:0004177	aminopeptidase activity

0.42	GO:0005576	extracellular region
0.41	GO:0036457	keratohyalin granule
0.34	GO:0001669	acrosomal vesicle
0.34	GO:0046658	anchored component of plasma membrane
0.34	GO:0019897	extrinsic component of plasma membrane
0.34	GO:0005829	cytosol
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.69	EC:3.4.21	GO:0004252
0.33	KEGG:R03435	GO:0004435

tr|T1FN20|T1FN20_HELRO
Uncharacterized protein
Search

PAAF1

0.96	Proteasomal ATPase-associated factor 1

0.39	GO:0070682	proteasome regulatory particle assembly
0.37	GO:0006511	ubiquitin-dependent protein catabolic process
0.36	GO:0016032	viral process
0.35	GO:0006457	protein folding
0.34	GO:0032259	methylation
0.33	GO:0007165	signal transduction

0.37	GO:0005515	protein binding
0.34	GO:0008168	methyltransferase activity
0.34	GO:0043531	ADP binding
0.34	GO:0003723	RNA binding

0.70	GO:1905369	endopeptidase complex
0.57	GO:0043234	protein complex
0.44	GO:0044424	intracellular part
0.34	GO:0043227	membrane-bounded organelle
0.33	GO:0019013	viral nucleocapsid
0.33	GO:1990904	ribonucleoprotein complex
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0008168

tr|T1FN21|T1FN21_HELRO
Uncharacterized protein
Search

HGD

0.49	Homogentisate 12-dioxygenase

0.81	GO:1902222	erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process
0.78	GO:0006570	tyrosine metabolic process
0.78	GO:0006558	L-phenylalanine metabolic process
0.76	GO:0009074	aromatic amino acid family catabolic process
0.71	GO:0042737	drug catabolic process
0.53	GO:0055114	oxidation-reduction process
0.34	GO:0001731	formation of translation preinitiation complex
0.34	GO:0006446	regulation of translational initiation

0.82	GO:0004411	homogentisate 1,2-dioxygenase activity
0.37	GO:0042802	identical protein binding
0.34	GO:0031369	translation initiation factor binding
0.33	GO:0003743	translation initiation factor activity
0.33	GO:0046872	metal ion binding

0.35	GO:0070062	extracellular exosome
0.34	GO:0055120	striated muscle dense body
0.34	GO:0016282	eukaryotic 43S preinitiation complex
0.34	GO:0033290	eukaryotic 48S preinitiation complex
0.34	GO:0005852	eukaryotic translation initiation factor 3 complex

0.82	EC:1.13.11.5	GO:0004411
0.82	KEGG:R02519	GO:0004411

tr|T1FN22|T1FN22_HELRO
Uncharacterized protein
Search

ACTR1A

0.92	alpha-centractin

0.42	GO:0019896	axonal transport of mitochondrion
0.42	GO:0008090	retrograde axonal transport
0.41	GO:0008089	anterograde axonal transport
0.37	GO:0007283	spermatogenesis
0.37	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.35	GO:0097711	ciliary basal body-plasma membrane docking
0.35	GO:0000278	mitotic cell cycle
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0044839	cell cycle G2/M phase transition
0.34	GO:0010389	regulation of G2/M transition of mitotic cell cycle

0.52	GO:0032559	adenyl ribonucleotide binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005200	structural constituent of cytoskeleton
0.34	GO:0005515	protein binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding

0.82	GO:0005869	dynactin complex
0.56	GO:0005813	centrosome
0.52	GO:0099738	cell cortex region
0.52	GO:0043209	myelin sheath
0.41	GO:1904115	axon cytoplasm
0.38	GO:0002177	manchette
0.38	GO:0070062	extracellular exosome
0.37	GO:0005814	centriole
0.37	GO:0030137	COPI-coated vesicle
0.35	GO:1904813	ficolin-1-rich granule lumen

tr|T1FN23|T1FN23_HELRO
Uncharacterized protein
Search

tr|T1FN24|T1FN24_HELRO
Uncharacterized protein
Search

WDR92

0.95	LOW QUALITY PROTEIN: WD repeat-containing protein 92

0.49

GO:0006915

apoptotic process

0.66	GO:0043130	ubiquitin binding
0.60	GO:0005509	calcium ion binding

0.30

GO:0016021

integral component of membrane

tr|T1FN25|T1FN25_HELRO
Uncharacterized protein
Search

PRDX6

0.41	Glutathione peroxidase

0.69	GO:0098869	cellular oxidant detoxification
0.68	GO:0045454	cell redox homeostasis
0.53	GO:0055114	oxidation-reduction process
0.51	GO:0048026	positive regulation of mRNA splicing, via spliceosome
0.49	GO:0046475	glycerophospholipid catabolic process
0.44	GO:0006979	response to oxidative stress
0.37	GO:0042744	hydrogen peroxide catabolic process
0.37	GO:0032060	bleb assembly
0.36	GO:1901700	response to oxygen-containing compound
0.35	GO:0043312	neutrophil degranulation

0.74	GO:0051920	peroxiredoxin activity
0.52	GO:0004601	peroxidase activity
0.52	GO:0047499	calcium-independent phospholipase A2 activity
0.48	GO:0045296	cadherin binding
0.47	GO:0031625	ubiquitin protein ligase binding
0.46	GO:0042803	protein homodimerization activity
0.42	GO:0102568	phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
0.42	GO:0102567	phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
0.33	GO:0009982	pseudouridine synthase activity
0.33	GO:0003723	RNA binding

0.47	GO:0048471	perinuclear region of cytoplasm
0.41	GO:0005634	nucleus
0.40	GO:0005764	lysosome
0.37	GO:0005615	extracellular space
0.37	GO:0005829	cytosol
0.36	GO:1903561	extracellular vesicle
0.35	GO:0034774	secretory granule lumen
0.35	GO:0005775	vacuolar lumen
0.34	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.74	EC:1.11.1.15	GO:0051920
0.52	KEGG:R03532	GO:0004601

tr|T1FN26|T1FN26_HELRO
Uncharacterized protein
Search

0.71	Regulatory particle triple-A ATPase 2, isoform B

0.81	GO:1901800	positive regulation of proteasomal protein catabolic process
0.70	GO:0030163	protein catabolic process
0.52	GO:0006508	proteolysis
0.43	GO:0043632	modification-dependent macromolecule catabolic process
0.42	GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly
0.41	GO:0034976	response to endoplasmic reticulum stress
0.40	GO:0010243	response to organonitrogen compound
0.38	GO:0044267	cellular protein metabolic process
0.36	GO:0006383	transcription by RNA polymerase III
0.35	GO:0008063	Toll signaling pathway

0.82	GO:0036402	proteasome-activating ATPase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0008233	peptidase activity
0.41	GO:0017025	TBP-class protein binding
0.34	GO:0008271	secondary active sulfate transmembrane transporter activity
0.33	GO:0003887	DNA-directed DNA polymerase activity
0.33	GO:0016758	transferase activity, transferring hexosyl groups
0.33	GO:0016788	hydrolase activity, acting on ester bonds

0.53	GO:1905369	endopeptidase complex
0.48	GO:0005737	cytoplasm
0.46	GO:0043234	protein complex
0.39	GO:0031981	nuclear lumen
0.35	GO:0055029	nuclear DNA-directed RNA polymerase complex
0.30	GO:0016020	membrane

0.50

GO:0008233

tr|T1FN27|T1FN27_HELRO
Sodium/potassium-transporting ATPase subunit alpha
Search

0.64	Sodium/potassium-transporting ATPase subunit alpha

0.84	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient
0.75	GO:0090662	ATP hydrolysis coupled transmembrane transport
0.72	GO:0006814	sodium ion transport
0.71	GO:0006813	potassium ion transport
0.43	GO:0030317	flagellated sperm motility
0.42	GO:0006937	regulation of muscle contraction
0.42	GO:0030004	cellular monovalent inorganic cation homeostasis
0.42	GO:0042391	regulation of membrane potential
0.41	GO:0007626	locomotory behavior
0.41	GO:1903416	response to glycoside

0.84	GO:0005391	sodium:potassium-exchanging ATPase activity
0.54	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.53	GO:0046872	metal ion binding
0.41	GO:1990239	steroid hormone binding
0.37	GO:0051087	chaperone binding
0.36	GO:0008900	potassium:proton exchanging ATPase activity
0.34	GO:0005234	extracellularly glutamate-gated ion channel activity

0.43	GO:0042383	sarcolemma
0.40	GO:0005890	sodium:potassium-exchanging ATPase complex
0.39	GO:0043209	myelin sheath
0.38	GO:0098590	plasma membrane region
0.37	GO:0030054	cell junction
0.37	GO:0098857	membrane microdomain
0.37	GO:0098794	postsynapse
0.36	GO:0044309	neuron spine
0.36	GO:0030425	dendrite
0.36	GO:1990794	basolateral part of cell

0.84

EC:3.6.3.9

GO:0005391

tr|T1FN28|T1FN28_HELRO
Uncharacterized protein
Search

DYNC1LI1

0.86	Cytoplasmic dynein light-intermediate chain 1

0.74	GO:0007018	microtubule-based movement
0.53	GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint
0.45	GO:0000226	microtubule cytoskeleton organization
0.40	GO:0048814	regulation of dendrite morphogenesis
0.40	GO:0048813	dendrite morphogenesis
0.40	GO:0048477	oogenesis
0.40	GO:0030705	cytoskeleton-dependent intracellular transport
0.39	GO:0007409	axonogenesis
0.39	GO:0051028	mRNA transport
0.37	GO:0009794	regulation of mitotic cell cycle, embryonic

0.75	GO:0003777	microtubule motor activity
0.55	GO:0045504	dynein heavy chain binding
0.51	GO:0019003	GDP binding
0.34	GO:0005525	GTP binding
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0008144	drug binding
0.33	GO:0003723	RNA binding
0.33	GO:0003735	structural constituent of ribosome
0.33	GO:0015078	hydrogen ion transmembrane transporter activity

0.83	GO:0005868	cytoplasmic dynein complex
0.51	GO:0005813	centrosome
0.49	GO:0000922	spindle pole
0.48	GO:0000776	kinetochore
0.39	GO:0043005	neuron projection
0.39	GO:0005635	nuclear envelope
0.36	GO:0000779	condensed chromosome, centromeric region
0.36	GO:0005874	microtubule
0.35	GO:0101003	ficolin-1-rich granule membrane
0.34	GO:0005770	late endosome

tr|T1FN29|T1FN29_HELRO
Uncharacterized protein
Search

EIF4A2

0.63	Eukaryotic initiation factor 4A-II

0.71	GO:0006413	translational initiation
0.44	GO:0010501	RNA secondary structure unwinding
0.43	GO:1900260	negative regulation of RNA-directed 5'-3' RNA polymerase activity
0.40	GO:1990823	response to leukemia inhibitory factor
0.39	GO:0071345	cellular response to cytokine stimulus
0.37	GO:0010468	regulation of gene expression
0.35	GO:0002181	cytoplasmic translation

0.77	GO:0004004	ATP-dependent RNA helicase activity
0.72	GO:0003743	translation initiation factor activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.41	GO:0005730	nucleolus
0.39	GO:0048471	perinuclear region of cytoplasm

tr|T1FN30|T1FN30_HELRO
Uncharacterized protein
Search

0.72	Myosin regulatory light chain A, smooth adductor muscle

0.40	GO:0000479	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.40	GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.39	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.38	GO:0000967	rRNA 5'-end processing
0.37	GO:0031126	snoRNA 3'-end processing
0.37	GO:0001522	pseudouridine synthesis
0.36	GO:0034964	box H/ACA snoRNA processing
0.36	GO:0040031	snRNA modification
0.35	GO:0016556	mRNA modification
0.35	GO:0006413	translational initiation

0.64	GO:0005509	calcium ion binding
0.39	GO:0003723	RNA binding
0.37	GO:0009982	pseudouridine synthase activity
0.36	GO:0004386	helicase activity
0.35	GO:0008092	cytoskeletal protein binding
0.35	GO:0005221	intracellular cyclic nucleotide activated cation channel activity
0.35	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.35	GO:0010521	telomerase inhibitor activity
0.35	GO:0008144	drug binding
0.34	GO:0030554	adenyl nucleotide binding

0.42	GO:0005730	nucleolus
0.42	GO:0030684	preribosome
0.40	GO:0005732	small nucleolar ribonucleoprotein complex
0.37	GO:0005856	cytoskeleton
0.35	GO:0043234	protein complex
0.34	GO:0016235	aggresome
0.33	GO:0005776	autophagosome
0.33	GO:0005654	nucleoplasm
0.33	GO:1902494	catalytic complex
0.33	GO:0097014	ciliary plasm

0.37

EC:5.4.99.12

GO:0009982

tr|T1FN31|T1FN31_HELRO
ATP-dependent (S)-NAD(P)H-hydrate dehydratase
Search

CARKD

0.74	ATP-dependent (S)-NAD(P)H-hydrate dehydratase

0.66	GO:0019362	pyridine nucleotide metabolic process
0.40	GO:0016310	phosphorylation
0.33	GO:0072525	pyridine-containing compound biosynthetic process
0.33	GO:0009108	coenzyme biosynthetic process
0.33	GO:0009165	nucleotide biosynthetic process

0.85	GO:0047453	ATP-dependent NAD(P)H-hydrate dehydratase activity
0.79	GO:0052855	ADP-dependent NAD(P)H-hydrate dehydratase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0052857	NADPHX epimerase activity
0.45	GO:0052856	NADHX epimerase activity
0.41	GO:0016301	kinase activity
0.33	GO:0005515	protein binding

0.47	GO:0005739	mitochondrion
0.42	GO:0005829	cytosol
0.41	GO:0009507	chloroplast
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.85	EC:4.2.1.93	GO:0047453
0.85	KEGG:R00129	GO:0047453

tr|T1FN32|T1FN32_HELRO
Uncharacterized protein
Search

0.67	60S acidic ribosomal protein P0

0.67

GO:0042254

ribosome biogenesis

0.33

GO:0016829

lyase activity

0.61	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:4

GO:0016829

tr|T1FN33|T1FN33_HELRO
Uncharacterized protein
Search

0.60	Peroxisomal membrane protein PEX16 (Fragment)

0.86	GO:0016557	peroxisome membrane biogenesis
0.85	GO:0022615	protein to membrane docking
0.85	GO:0032581	ER-dependent peroxisome organization
0.85	GO:0045046	protein import into peroxisome membrane
0.78	GO:0016558	protein import into peroxisome matrix
0.71	GO:0070972	protein localization to endoplasmic reticulum
0.35	GO:0006508	proteolysis

0.79	GO:0008022	protein C-terminus binding
0.36	GO:0004252	serine-type endopeptidase activity

0.78	GO:0031903	microbody membrane
0.78	GO:0044439	peroxisomal part
0.73	GO:0031301	integral component of organelle membrane
0.68	GO:0005789	endoplasmic reticulum membrane

0.36

GO:0004252

tr|T1FN34|T1FN34_HELRO
Uncharacterized protein
Search

0.48	Formin binding protein 1 like

0.69	GO:0006897	endocytosis
0.48	GO:0097320	plasma membrane tubulation
0.47	GO:0030050	vesicle transport along actin filament
0.46	GO:0051491	positive regulation of filopodium assembly
0.45	GO:0010324	membrane invagination
0.45	GO:0120036	plasma membrane bounded cell projection organization
0.44	GO:0006900	vesicle budding from membrane
0.42	GO:0030031	cell projection assembly
0.42	GO:0070925	organelle assembly
0.40	GO:0030708	germarium-derived female germ-line cyst encapsulation

0.44	GO:0045296	cadherin binding
0.42	GO:0051020	GTPase binding
0.40	GO:0032794	GTPase activating protein binding
0.39	GO:0008289	lipid binding
0.34	GO:0042802	identical protein binding
0.34	GO:0046982	protein heterodimerization activity
0.31	GO:0003677	DNA binding

0.44	GO:0031982	vesicle
0.41	GO:0005829	cytosol
0.39	GO:0097610	cell surface furrow
0.39	GO:0031594	neuromuscular junction
0.38	GO:0030496	midbody
0.38	GO:0032155	cell division site part
0.37	GO:0043229	intracellular organelle
0.37	GO:0005938	cell cortex
0.36	GO:0005886	plasma membrane
0.35	GO:0031090	organelle membrane

tr|T1FN35|T1FN35_HELRO
Uncharacterized protein
Search

0.75	GO:0046854	phosphatidylinositol phosphorylation
0.52	GO:0001958	endochondral ossification
0.52	GO:0002063	chondrocyte development
0.52	GO:0030204	chondroitin sulfate metabolic process
0.52	GO:0042733	embryonic digit morphogenesis
0.49	GO:0009791	post-embryonic development
0.45	GO:0016311	dephosphorylation
0.39	GO:0006021	inositol biosynthetic process
0.35	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process
0.34	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway

0.52	GO:0008254	3'-nucleotidase activity
0.40	GO:0008441	3'(2'),5'-bisphosphate nucleotidase activity
0.39	GO:0052832	inositol monophosphate 3-phosphatase activity
0.39	GO:0052833	inositol monophosphate 4-phosphatase activity
0.39	GO:0008934	inositol monophosphate 1-phosphatase activity
0.34	GO:0046872	metal ion binding
0.33	GO:0003678	DNA helicase activity
0.33	GO:0004871	signal transducer activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding

0.48	GO:0016604	nuclear body
0.46	GO:0005794	Golgi apparatus
0.45	GO:0005829	cytosol
0.34	GO:1905360	GTPase complex
0.34	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.33	GO:0098797	plasma membrane protein complex
0.30	GO:0016021	integral component of membrane

0.52

EC:3.1.3.6

GO:0008254

tr|T1FN36|T1FN36_HELRO
Uncharacterized protein
Search

RPS5

0.49	Ribosomal protein S5

0.59	GO:0043043	peptide biosynthetic process
0.54	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.37	GO:0000028	ribosomal small subunit assembly
0.34	GO:0009116	nucleoside metabolic process

0.62	GO:0003735	structural constituent of ribosome
0.57	GO:0003723	RNA binding
0.35	GO:0004731	purine-nucleoside phosphorylase activity

0.68	GO:0015935	small ribosomal subunit
0.37	GO:0022626	cytosolic ribosome

0.35

EC:2.4.2.1

GO:0004731

tr|T1FN37|T1FN37_HELRO
Uncharacterized protein
Search

TSG101

0.93	Tumor susceptibility protein 101

0.65	GO:0015031	protein transport
0.60	GO:0036211	protein modification process
0.56	GO:0044267	cellular protein metabolic process
0.53	GO:1903774	positive regulation of viral budding via host ESCRT complex
0.53	GO:2000395	regulation of ubiquitin-dependent endocytosis
0.53	GO:1903551	regulation of extracellular exosome assembly
0.52	GO:1990182	exosomal secretion
0.52	GO:1903543	positive regulation of exosomal secretion
0.52	GO:1902188	positive regulation of viral release from host cell
0.52	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity

0.53	GO:0046790	virion binding
0.51	GO:0048306	calcium-dependent protein binding
0.49	GO:0043130	ubiquitin binding
0.49	GO:0003714	transcription corepressor activity
0.48	GO:0031625	ubiquitin protein ligase binding
0.46	GO:0042803	protein homodimerization activity
0.46	GO:0032403	protein complex binding
0.34	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.33	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
0.32	GO:0003677	DNA binding

0.49	GO:0000813	ESCRT I complex
0.49	GO:0070062	extracellular exosome
0.48	GO:0005770	late endosome
0.48	GO:0005769	early endosome
0.46	GO:0005730	nucleolus
0.44	GO:0005829	cytosol
0.40	GO:0005886	plasma membrane
0.35	GO:0090543	Flemming body
0.34	GO:0005815	microtubule organizing center
0.33	GO:0044216	other organism cell

0.33

EC:1.1.1

GO:0016616

tr|T1FN38|T1FN38_HELRO
Mitogen-activated protein kinase
Search

0.59	Mitogen-activated protein kinase

0.80	GO:0000165	MAPK cascade
0.42	GO:0046534	positive regulation of photoreceptor cell differentiation
0.42	GO:0034334	adherens junction maintenance
0.42	GO:0071243	cellular response to arsenic-containing substance
0.42	GO:0008586	imaginal disc-derived wing vein morphogenesis
0.42	GO:0007474	imaginal disc-derived wing vein specification
0.41	GO:0048149	behavioral response to ethanol
0.41	GO:2000826	regulation of heart morphogenesis
0.41	GO:0016242	negative regulation of macroautophagy
0.41	GO:0071276	cellular response to cadmium ion

0.82	GO:0004707	MAP kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0019901	protein kinase binding
0.38	GO:0008134	transcription factor binding
0.34	GO:0004713	protein tyrosine kinase activity

0.45	GO:0005622	intracellular
0.41	GO:0031594	neuromuscular junction
0.39	GO:0030054	cell junction
0.37	GO:0043227	membrane-bounded organelle
0.30	GO:0016020	membrane

0.82	EC:2.7.11.24	GO:0004707
0.82	KEGG:R00162	GO:0004707

tr|T1FN39|T1FN39_HELRO
Uncharacterized protein
Search

0.36	GO:0071108	protein K48-linked deubiquitination
0.33	GO:0016567	protein ubiquitination

0.54	GO:0046872	metal ion binding
0.46	GO:0016874	ligase activity
0.36	GO:1990380	Lys48-specific deubiquitinase activity
0.36	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.32	GO:0003677	DNA binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0016740	transferase activity

0.30

GO:0031224

intrinsic component of membrane

0.46

GO:0016874

tr|T1FN40|T1FN40_HELRO
Uncharacterized protein
Search

PSMD14

0.85	Jun activation domain binding protein rpn11

0.85	GO:0070536	protein K63-linked deubiquitination
0.42	GO:0001878	response to yeast
0.41	GO:0010950	positive regulation of endopeptidase activity
0.41	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.41	GO:0006303	double-strand break repair via nonhomologous end joining
0.41	GO:0061136	regulation of proteasomal protein catabolic process
0.40	GO:0000724	double-strand break repair via homologous recombination
0.35	GO:0008063	Toll signaling pathway
0.34	GO:0045471	response to ethanol
0.34	GO:0007623	circadian rhythm

0.85	GO:0061578	Lys63-specific deubiquitinase activity
0.43	GO:0061133	endopeptidase activator activity
0.42	GO:0070628	proteasome binding
0.41	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.34	GO:0008237	metallopeptidase activity
0.33	GO:0004175	endopeptidase activity
0.33	GO:0046872	metal ion binding

0.67	GO:1905369	endopeptidase complex
0.55	GO:0043234	protein complex
0.43	GO:0044424	intracellular part
0.34	GO:0048786	presynaptic active zone
0.33	GO:0043233	organelle lumen
0.32	GO:0043227	membrane-bounded organelle
0.30	GO:0016020	membrane

0.41

GO:0036459

tr|T1FN41|T1FN41_HELRO
Uncharacterized protein
Search

API5

0.94	Apoptosis inhibitor 5-B

0.83	GO:2000270	negative regulation of fibroblast apoptotic process
0.52	GO:0006915	apoptotic process

0.85	GO:0017134	fibroblast growth factor binding
0.36	GO:0003723	RNA binding

0.77	GO:0016607	nuclear speck
0.70	GO:0005681	spliceosomal complex
0.37	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|T1FN42|T1FN42_HELRO
Uncharacterized protein
Search

PHYHD1

0.49	Peroxisomal phytanoyl-CoA hydroxylase

0.52	GO:0055114	oxidation-reduction process
0.37	GO:0090521	glomerular visceral epithelial cell migration

0.70	GO:0051213	dioxygenase activity
0.37	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.37	GO:0046872	metal ion binding
0.36	GO:0017056	structural constituent of nuclear pore
0.34	GO:0005515	protein binding

0.34	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.37

GO:0016705

tr|T1FN43|T1FN43_HELRO
Uncharacterized protein
Search

LIPT1

0.88	Lipoyltransferase 1, mitochondrial

0.77	GO:0009249	protein lipoylation
0.35	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c
0.34	GO:0000395	mRNA 5'-splice site recognition
0.33	GO:0000387	spliceosomal snRNP assembly
0.33	GO:0006629	lipid metabolic process

0.46	GO:0016979	lipoate-protein ligase activity
0.34	GO:0016746	transferase activity, transferring acyl groups
0.34	GO:0030619	U1 snRNA binding
0.33	GO:0003729	mRNA binding
0.32	GO:0008270	zinc ion binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.41	GO:0005739	mitochondrion
0.35	GO:0045275	respiratory chain complex III
0.34	GO:0044446	intracellular organelle part
0.33	GO:0031090	organelle membrane
0.33	GO:0031975	envelope
0.33	GO:0120114	Sm-like protein family complex
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0005634	nucleus
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016021	integral component of membrane

0.46

EC:6.3.4

GO:0016979

tr|T1FN44|T1FN44_HELRO
Uncharacterized protein
Search

ALYREF

0.60	RNA and export factor-binding protein 2

0.39	GO:0046784	viral mRNA export from host cell nucleus
0.38	GO:0001649	osteoblast differentiation
0.38	GO:0031297	replication fork processing
0.38	GO:0032786	positive regulation of DNA-templated transcription, elongation
0.38	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.37	GO:0000018	regulation of DNA recombination
0.37	GO:0051028	mRNA transport
0.37	GO:0006405	RNA export from nucleus
0.34	GO:0010467	gene expression

0.59	GO:0003723	RNA binding
0.37	GO:0003697	single-stranded DNA binding

0.50	GO:0016607	nuclear speck
0.38	GO:0035145	exon-exon junction complex
0.38	GO:0000346	transcription export complex
0.38	GO:0071013	catalytic step 2 spliceosome
0.38	GO:0000784	nuclear chromosome, telomeric region
0.38	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

tr|T1FN45|T1FN45_HELRO
Uncharacterized protein
Search

0.94	Theromacin

0.72

GO:0006952

defense response

0.66

GO:0005576

extracellular region

tr|T1FN46|T1FN46_HELRO
Uncharacterized protein
Search

tr|T1FN47|T1FN47_HELRO
Uncharacterized protein
Search

0.39	50S ribosome-binding GTPase

0.63	GO:0051301	cell division
0.63	GO:0007049	cell cycle
0.41	GO:0043065	positive regulation of apoptotic process
0.36	GO:0007224	smoothened signaling pathway
0.35	GO:0060271	cilium assembly
0.35	GO:0007349	cellularization
0.33	GO:0005978	glycogen biosynthetic process
0.33	GO:0006468	protein phosphorylation

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0031625	ubiquitin protein ligase binding
0.41	GO:0042803	protein homodimerization activity
0.39	GO:0003924	GTPase activity
0.34	GO:0004689	phosphorylase kinase activity
0.34	GO:0005516	calmodulin binding
0.32	GO:0030554	adenyl nucleotide binding

0.43	GO:0031105	septin complex
0.36	GO:0060170	ciliary membrane
0.36	GO:0097610	cell surface furrow
0.36	GO:0030496	midbody
0.35	GO:0032155	cell division site part
0.35	GO:0005819	spindle
0.34	GO:0070938	contractile ring
0.34	GO:0005940	septin ring
0.34	GO:0005964	phosphorylase kinase complex
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:2.7.11.19

GO:0004689

tr|T1FN49|T1FN49_HELRO
Uncharacterized protein
Search

VMP1

0.94	Vacuole membrane protein 1

0.52	GO:0034329	cell junction assembly
0.52	GO:0007566	embryo implantation
0.50	GO:0006914	autophagy
0.50	GO:0098609	cell-cell adhesion
0.49	GO:0007030	Golgi organization
0.46	GO:0007029	endoplasmic reticulum organization
0.45	GO:0032940	secretion by cell
0.42	GO:0016192	vesicle-mediated transport
0.39	GO:0002790	peptide secretion
0.38	GO:0015031	protein transport

0.35	GO:0005515	protein binding
0.34	GO:0005198	structural molecule activity

0.54	GO:0000407	phagophore assembly site
0.51	GO:0005783	endoplasmic reticulum
0.48	GO:0005730	nucleolus
0.42	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane
0.40	GO:0005774	vacuolar membrane
0.39	GO:0005776	autophagosome
0.36	GO:0005886	plasma membrane
0.34	GO:0071439	clathrin complex
0.34	GO:0030130	clathrin coat of trans-Golgi network vesicle
0.34	GO:0005905	clathrin-coated pit

tr|T1FN50|T1FN50_HELRO
Uncharacterized protein
Search

PMPCB

0.83	Mitochondrial-processing peptidase subunit beta

0.83	GO:0006627	protein processing involved in protein targeting to mitochondrion
0.43	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c
0.40	GO:0009060	aerobic respiration
0.35	GO:0007186	G-protein coupled receptor signaling pathway
0.35	GO:0006851	mitochondrial calcium ion transmembrane transport

0.70	GO:0004222	metalloendopeptidase activity
0.54	GO:0046872	metal ion binding
0.35	GO:0004930	G-protein coupled receptor activity

0.85	GO:0017087	mitochondrial processing peptidase complex
0.46	GO:0005750	mitochondrial respiratory chain complex III
0.30	GO:0016021	integral component of membrane

0.70

GO:0004222

tr|T1FN51|T1FN51_HELRO
Polyadenylate-binding protein
Search

PABPC1

0.63	Polyadenylate-binding protein 1-B

0.47	GO:2000623	negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.45	GO:0045070	positive regulation of viral genome replication
0.41	GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
0.40	GO:0031047	gene silencing by RNA
0.39	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.39	GO:0043488	regulation of mRNA stability
0.38	GO:0006397	mRNA processing
0.38	GO:0008380	RNA splicing
0.37	GO:0043489	RNA stabilization
0.37	GO:0061515	myeloid cell development

0.59	GO:0003723	RNA binding
0.44	GO:0008022	protein C-terminus binding
0.35	GO:0031370	eukaryotic initiation factor 4G binding
0.35	GO:0008494	translation activator activity
0.35	GO:0043621	protein self-association

0.48	GO:0005737	cytoplasm
0.44	GO:0035770	ribonucleoprotein granule
0.43	GO:0071013	catalytic step 2 spliceosome
0.37	GO:1990124	messenger ribonucleoprotein complex
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.36	GO:0030425	dendrite
0.34	GO:0005844	polysome
0.30	GO:0016020	membrane

tr|T1FN52|T1FN52_HELRO
Tetraspanin
Search

0.24	Tetraspanin

0.37	GO:0007166	cell surface receptor signaling pathway
0.36	GO:0042098	T cell proliferation
0.35	GO:1900746	regulation of vascular endothelial growth factor signaling pathway
0.35	GO:0050931	pigment cell differentiation
0.35	GO:0035188	hatching
0.35	GO:0016477	cell migration

0.35

GO:0005178

integrin binding

0.37	GO:0005887	integral component of plasma membrane
0.35	GO:0005604	basement membrane
0.35	GO:0005770	late endosome
0.35	GO:0005764	lysosome

tr|T1FN53|T1FN53_HELRO
Uncharacterized protein
Search

0.69	ATP synthase subunit s, mitochondrial

0.63	GO:0008270	zinc ion binding
0.59	GO:0003723	RNA binding

tr|T1FN54|T1FN54_HELRO
Uncharacterized protein
Search

0.90	AarF domain-containing protein kinase 4

0.69	GO:0006744	ubiquinone biosynthetic process
0.47	GO:0016310	phosphorylation
0.45	GO:0032836	glomerular basement membrane development
0.44	GO:0072015	glomerular visceral epithelial cell development
0.43	GO:0021692	cerebellar Purkinje cell layer morphogenesis
0.34	GO:0044267	cellular protein metabolic process
0.34	GO:0036211	protein modification process
0.34	GO:0007018	microtubule-based movement
0.33	GO:0043043	peptide biosynthetic process
0.33	GO:0010467	gene expression

0.48	GO:0016301	kinase activity
0.38	GO:0043531	ADP binding
0.34	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.34	GO:0005524	ATP binding
0.34	GO:0140096	catalytic activity, acting on a protein
0.34	GO:0035091	phosphatidylinositol binding
0.34	GO:0003735	structural constituent of ribosome
0.34	GO:0003777	microtubule motor activity
0.34	GO:0008017	microtubule binding
0.33	GO:0016788	hydrolase activity, acting on ester bonds

0.56	GO:0005739	mitochondrion
0.34	GO:0005829	cytosol
0.34	GO:0031967	organelle envelope
0.34	GO:0031090	organelle membrane
0.33	GO:0005840	ribosome
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.34

GO:0016773

tr|T1FN55|T1FN55_HELRO
Uncharacterized protein
Search

tr|T1FN56|T1FN56_HELRO
Uncharacterized protein
Search

0.68	GO:0048858	cell projection morphogenesis
0.59	GO:0003352	regulation of cilium movement
0.56	GO:0048488	synaptic vesicle endocytosis
0.56	GO:0060271	cilium assembly
0.53	GO:0046856	phosphatidylinositol dephosphorylation
0.42	GO:0090660	cerebrospinal fluid circulation
0.41	GO:0072114	pronephros morphogenesis
0.40	GO:0007368	determination of left/right symmetry

0.56	GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity
0.43	GO:0003723	RNA binding

0.51	GO:0045202	synapse
0.49	GO:0005929	cilium
0.46	GO:0005856	cytoskeleton
0.42	GO:0005829	cytosol
0.38	GO:0005634	nucleus

tr|T1FN57|T1FN57_HELRO
V-type proton ATPase proteolipid subunit
Search

0.62	V-type proton ATPase proteolipid subunit

0.76	GO:0015991	ATP hydrolysis coupled proton transport
0.48	GO:0007033	vacuole organization
0.46	GO:0007035	vacuolar acidification
0.43	GO:0030177	positive regulation of Wnt signaling pathway
0.40	GO:0060035	notochord cell development
0.40	GO:0001878	response to yeast
0.40	GO:0060059	embryonic retina morphogenesis in camera-type eye
0.39	GO:0006623	protein targeting to vacuole
0.39	GO:0006878	cellular copper ion homeostasis
0.38	GO:0006879	cellular iron ion homeostasis

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.44	GO:0036442	proton-exporting ATPase activity
0.42	GO:0031625	ubiquitin protein ligase binding
0.42	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
0.34	GO:0005245	voltage-gated calcium channel activity
0.34	GO:0008448	N-acetylglucosamine-6-phosphate deacetylase activity

0.78	GO:0033179	proton-transporting V-type ATPase, V0 domain
0.76	GO:0005774	vacuolar membrane
0.37	GO:0033181	plasma membrane proton-transporting V-type ATPase complex
0.36	GO:0045169	fusome
0.35	GO:0099503	secretory vesicle
0.35	GO:0005766	primary lysosome
0.35	GO:0030670	phagocytic vesicle membrane
0.34	GO:0048786	presynaptic active zone
0.34	GO:0012505	endomembrane system
0.34	GO:0005925	focal adhesion

0.34

EC:3.5.1.25

GO:0008448

tr|T1FN58|T1FN58_HELRO
Uncharacterized protein
Search

CA5B

0.42	Cytoplasmic carbonic anydrase

0.69	GO:0006730	one-carbon metabolic process
0.40	GO:2000021	regulation of ion homeostasis
0.37	GO:2001225	regulation of chloride transport
0.37	GO:0032230	positive regulation of synaptic transmission, GABAergic
0.36	GO:0051453	regulation of intracellular pH
0.36	GO:0032846	positive regulation of homeostatic process
0.35	GO:2000878	positive regulation of oligopeptide transport
0.35	GO:2001148	regulation of dipeptide transmembrane transport
0.35	GO:0015670	carbon dioxide transport
0.35	GO:0038166	angiotensin-activated signaling pathway

0.76	GO:0004089	carbonate dehydratase activity
0.61	GO:0008270	zinc ion binding
0.36	GO:0004064	arylesterase activity
0.33	GO:0005198	structural molecule activity

0.46	GO:0005739	mitochondrion
0.41	GO:0031225	anchored component of membrane
0.36	GO:0005886	plasma membrane
0.34	GO:0005829	cytosol
0.34	GO:0043209	myelin sheath
0.34	GO:0045177	apical part of cell
0.33	GO:0030117	membrane coat
0.33	GO:0043233	organelle lumen
0.32	GO:0044446	intracellular organelle part
0.32	GO:0005840	ribosome

0.76

EC:4.2.1.1

GO:0004089

tr|T1FN59|T1FN59_HELRO
Uncharacterized protein
Search

0.90	GDP-mannose pyrophosphorylase Aa

0.49	GO:0009058	biosynthetic process
0.38	GO:0019673	GDP-mannose metabolic process
0.32	GO:0006518	peptide metabolic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0010467	gene expression

0.63	GO:0016779	nucleotidyltransferase activity
0.35	GO:0032550	purine ribonucleoside binding
0.35	GO:0019001	guanyl nucleotide binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding
0.33	GO:0003743	translation initiation factor activity

0.34	GO:0070062	extracellular exosome
0.33	GO:0019028	viral capsid
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.63

EC:2.7.7

GO:0016779

tr|T1FN60|T1FN60_HELRO
GTP-binding nuclear protein
Search

0.72	GTP-binding nuclear protein Ran

0.72	GO:0006913	nucleocytoplasmic transport
0.65	GO:0015031	protein transport
0.42	GO:0048477	oogenesis
0.41	GO:0034504	protein localization to nucleus
0.41	GO:0009792	embryo development ending in birth or egg hatching
0.41	GO:0033750	ribosome localization
0.40	GO:0071166	ribonucleoprotein complex localization
0.40	GO:0051169	nuclear transport
0.40	GO:0051656	establishment of organelle localization
0.40	GO:0051236	establishment of RNA localization

0.67	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0000287	magnesium ion binding
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm
0.34	GO:0000777	condensed chromosome kinetochore
0.33	GO:0012505	endomembrane system
0.33	GO:0031967	organelle envelope

tr|T1FN61|T1FN61_HELRO
Eukaryotic translation initiation factor 3 subunit D
Search

0.71	Eukaryotic translation initiation factor 3 subunit D

0.80	GO:0002191	cap-dependent translational initiation
0.73	GO:0006446	regulation of translational initiation
0.73	GO:0001731	formation of translation preinitiation complex
0.36	GO:0032012	regulation of ARF protein signal transduction
0.36	GO:0007034	vacuolar transport
0.34	GO:0065009	regulation of molecular function

0.80	GO:0098808	mRNA cap binding
0.73	GO:0003743	translation initiation factor activity
0.36	GO:0005086	ARF guanyl-nucleotide exchange factor activity
0.33	GO:0008270	zinc ion binding

0.78	GO:0005852	eukaryotic translation initiation factor 3 complex
0.72	GO:0016282	eukaryotic 43S preinitiation complex
0.72	GO:0033290	eukaryotic 48S preinitiation complex
0.38	GO:0005634	nucleus
0.34	GO:1905369	endopeptidase complex
0.33	GO:0005829	cytosol

tr|T1FN62|T1FN62_HELRO
Uncharacterized protein
Search

WDR61

0.79	WD repeat and SOCS box-containing protein 2

0.86	GO:2001162	positive regulation of histone H3-K79 methylation
0.85	GO:0051571	positive regulation of histone H3-K4 methylation
0.85	GO:0080182	histone H3-K4 trimethylation
0.83	GO:0045638	negative regulation of myeloid cell differentiation
0.80	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter
0.45	GO:0016055	Wnt signaling pathway
0.39	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
0.39	GO:0006351	transcription, DNA-templated
0.37	GO:0016567	protein ubiquitination
0.36	GO:0006468	protein phosphorylation

0.40	GO:0016905	myosin heavy chain kinase activity
0.36	GO:0005515	protein binding

0.85	GO:0055087	Ski complex
0.84	GO:0035327	transcriptionally active chromatin
0.80	GO:0016593	Cdc73/Paf1 complex
0.66	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.40

EC:2.7.11.7

GO:0016905

tr|T1FN63|T1FN63_HELRO
Proteasome subunit alpha type
Search

PSMA5

0.49	Proteasome endopeptidase complex

0.78	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0045595	regulation of cell differentiation
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.35	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0051005	negative regulation of lipoprotein lipase activity
0.35	GO:0038180	nerve growth factor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway
0.35	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia

0.77	GO:0004298	threonine-type endopeptidase activity
0.35	GO:0030379	neurotensin receptor activity, non-G-protein coupled
0.35	GO:0010465	nerve growth factor receptor activity
0.35	GO:0048406	nerve growth factor binding
0.33	GO:0019899	enzyme binding

0.79	GO:0019773	proteasome core complex, alpha-subunit complex
0.59	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.35	GO:0097708	intracellular vesicle
0.35	GO:0031983	vesicle lumen
0.34	GO:0070013	intracellular organelle lumen
0.34	GO:0012505	endomembrane system
0.34	GO:0098589	membrane region
0.34	GO:0044446	intracellular organelle part

0.77

EC:3.4.25

GO:0004298

tr|T1FN64|T1FN64_HELRO
Uncharacterized protein
Search

tr|T1FN65|T1FN65_HELRO
Uncharacterized protein
Search

0.73	DNA-directed RNA polymerase II

0.58	GO:0006351	transcription, DNA-templated
0.34	GO:0035019	somatic stem cell population maintenance
0.34	GO:0032481	positive regulation of type I interferon production
0.34	GO:0060964	regulation of gene silencing by miRNA
0.34	GO:0045815	positive regulation of gene expression, epigenetic
0.34	GO:0008543	fibroblast growth factor receptor signaling pathway
0.34	GO:0016073	snRNA metabolic process
0.34	GO:0050434	positive regulation of viral transcription
0.34	GO:0006283	transcription-coupled nucleotide-excision repair
0.34	GO:0000398	mRNA splicing, via spliceosome

0.70	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.55	GO:0003677	DNA binding
0.34	GO:0005515	protein binding
0.32	GO:0008168	methyltransferase activity

0.61	GO:0005634	nucleus
0.44	GO:0000428	DNA-directed RNA polymerase complex
0.42	GO:0031974	membrane-enclosed lumen
0.39	GO:0044446	intracellular organelle part
0.37	GO:0043232	intracellular non-membrane-bounded organelle
0.34	GO:1905369	endopeptidase complex
0.33	GO:0005829	cytosol
0.33	GO:0043234	protein complex

0.70

GO:0003899

tr|T1FN66|T1FN66_HELRO
Uncharacterized protein
Search

0.69	Ribosomal protein lateral stalk subunit P2

0.69	GO:0006414	translational elongation
0.38	GO:0002181	cytoplasmic translation
0.34	GO:0016042	lipid catabolic process
0.32	GO:0042254	ribosome biogenesis

0.63	GO:0003735	structural constituent of ribosome
0.32	GO:0016787	hydrolase activity

0.61	GO:0005840	ribosome
0.37	GO:0044445	cytosolic part
0.35	GO:0044446	intracellular organelle part

0.32

GO:0016787

tr|T1FN67|T1FN67_HELRO
Uncharacterized protein
Search

PLOD3

0.79	Procollagen lysine 2-oxoglutarate 5-dioxygenase 3

0.54	GO:0046947	hydroxylysine biosynthetic process
0.53	GO:0017185	peptidyl-lysine hydroxylation
0.52	GO:0055114	oxidation-reduction process
0.52	GO:0001886	endothelial cell morphogenesis
0.52	GO:0070831	basement membrane assembly
0.51	GO:0030199	collagen fibril organization
0.51	GO:0042311	vasodilation
0.51	GO:0048730	epidermis morphogenesis
0.51	GO:0060425	lung morphogenesis
0.51	GO:0032963	collagen metabolic process

0.76	GO:0031418	L-ascorbic acid binding
0.76	GO:0008475	procollagen-lysine 5-dioxygenase activity
0.61	GO:0005506	iron ion binding
0.55	GO:0033823	procollagen glucosyltransferase activity
0.35	GO:0050211	procollagen galactosyltransferase activity
0.33	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
0.33	GO:0005515	protein binding

0.61	GO:0005783	endoplasmic reticulum
0.48	GO:0005802	trans-Golgi network
0.46	GO:0031012	extracellular matrix
0.39	GO:0005581	collagen trimer
0.37	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0098588	bounding membrane of organelle
0.36	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.76

EC:1.14.11.4

GO:0008475

tr|T1FN68|T1FN68_HELRO
Uncharacterized protein
Search

RPL5

0.58	Ribosomal protein L5

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.47	GO:0000027	ribosomal large subunit assembly
0.44	GO:2000435	negative regulation of protein neddylation
0.43	GO:2000059	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.43	GO:1904667	negative regulation of ubiquitin protein ligase activity
0.42	GO:1901796	regulation of signal transduction by p53 class mediator
0.41	GO:0050821	protein stabilization

0.79	GO:0008097	5S rRNA binding
0.64	GO:0003735	structural constituent of ribosome
0.44	GO:1990948	ubiquitin ligase inhibitor activity
0.42	GO:0003730	mRNA 3'-UTR binding
0.41	GO:0048027	mRNA 5'-UTR binding
0.41	GO:0031625	ubiquitin protein ligase binding
0.32	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.61	GO:0005840	ribosome
0.44	GO:0005829	cytosol
0.42	GO:0005730	nucleolus
0.39	GO:0005783	endoplasmic reticulum
0.39	GO:0005654	nucleoplasm
0.37	GO:0043234	protein complex
0.34	GO:0005925	focal adhesion
0.34	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.32

EC:3.2.1

GO:0004553

tr|T1FN69|T1FN69_HELRO
Uncharacterized protein
Search

0.41	Atp synthase lipid-binding mitochondrial

0.76	GO:0015991	ATP hydrolysis coupled proton transport
0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process

0.71	GO:0008289	lipid binding
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.38	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
0.38	GO:0019829	cation-transporting ATPase activity
0.33	GO:0005515	protein binding

0.72	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)
0.39	GO:0005753	mitochondrial proton-transporting ATP synthase complex
0.30	GO:0016021	integral component of membrane

tr|T1FN70|T1FN70_HELRO
Uncharacterized protein
Search

NSA2

0.80	TGF beta-inducible nuclear protein 1

0.66	GO:0000470	maturation of LSU-rRNA
0.65	GO:0000460	maturation of 5.8S rRNA
0.38	GO:0043043	peptide biosynthetic process
0.37	GO:0051260	protein homooligomerization
0.37	GO:0044267	cellular protein metabolic process
0.36	GO:0009059	macromolecule biosynthetic process

0.39	GO:0003735	structural constituent of ribosome
0.37	GO:0003723	RNA binding

0.65	GO:0030687	preribosome, large subunit precursor
0.60	GO:0005730	nucleolus
0.51	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

tr|T1FN71|T1FN71_HELRO
Uncharacterized protein
Search

tr|T1FN72|T1FN72_HELRO
Uncharacterized protein
Search

GRTP1

0.93	Growth hormone-regulated TBC protein 1-A

0.76	GO:0031338	regulation of vesicle fusion
0.76	GO:0090630	activation of GTPase activity
0.63	GO:0006886	intracellular protein transport

0.73	GO:0017137	Rab GTPase binding
0.70	GO:0005096	GTPase activator activity
0.40	GO:0016787	hydrolase activity

0.61	GO:0012505	endomembrane system
0.43	GO:0005622	intracellular
0.30	GO:0044425	membrane part

0.40

GO:0016787

tr|T1FN73|T1FN73_HELRO
Uncharacterized protein
Search

HSDL2

0.77	Hydroxysteroid dehydrogenase like protein 2

0.45

GO:0055114

oxidation-reduction process

0.46	GO:0016491	oxidoreductase activity
0.35	GO:0003723	RNA binding

0.72	GO:0042579	microbody
0.57	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.46

GO:0016491

tr|T1FN74|T1FN74_HELRO
Uncharacterized protein
Search

0.57	Ng-dimethylarginine dimethylaminohydrolase

0.38	GO:0000052	citrulline metabolic process
0.37	GO:0045429	positive regulation of nitric oxide biosynthetic process
0.36	GO:0006527	arginine catabolic process

0.51	GO:0016787	hydrolase activity
0.35	GO:0016740	transferase activity

0.30

GO:0044425

membrane part

0.51

GO:0016787

tr|T1FN75|T1FN75_HELRO
Gamma-glutamylcyclotransferase
Search

CHAC2

0.49	Glutathione-specific gamma-glutamylcyclotransferase 2

0.79	GO:0006751	glutathione catabolic process
0.34	GO:0006750	glutathione biosynthetic process

0.81	GO:0003839	gamma-glutamylcyclotransferase activity
0.61	GO:0016829	lyase activity

0.37

GO:0005829

cytosol

0.81

EC:2.3.2.4

GO:0003839

tr|T1FN76|T1FN76_HELRO
Tetraspanin
Search

0.32	Tetraspanin

0.39

GO:0071436

sodium ion export

0.39	GO:0008948	oxaloacetate decarboxylase activity
0.38	GO:0015081	sodium ion transmembrane transporter activity

0.30

GO:0016021

integral component of membrane

0.39	EC:1.1.1.38 EC:1.1.1.40 EC:4.1.1.3	GO:0008948
0.39	KEGG:R00217	GO:0008948

tr|T1FN77|T1FN77_HELRO
Uncharacterized protein
Search

NDUFS1

0.84	NADH-ubiquinone oxidoreductase subunit, mitochondrial

0.69	GO:0042773	ATP synthesis coupled electron transport
0.51	GO:0008637	apoptotic mitochondrial changes
0.47	GO:0051881	regulation of mitochondrial membrane potential
0.43	GO:0072593	reactive oxygen species metabolic process
0.34	GO:0032784	regulation of DNA-templated transcription, elongation
0.33	GO:0006357	regulation of transcription by RNA polymerase II

0.69	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.64	GO:0051536	iron-sulfur cluster binding
0.61	GO:0009055	electron transfer activity
0.34	GO:0000991	transcription factor activity, core RNA polymerase II binding
0.33	GO:0046872	metal ion binding
0.32	GO:0003677	DNA binding

0.49	GO:0005747	mitochondrial respiratory chain complex I
0.46	GO:0045272	plasma membrane respiratory chain complex I
0.46	GO:0043209	myelin sheath
0.45	GO:0005758	mitochondrial intermembrane space
0.30	GO:0031224	intrinsic component of membrane

0.69

EC:1.6.5.3

GO:0008137

tr|T1FN78|T1FN78_HELRO
Inosine triphosphate pyrophosphatase
Search

ITPA

0.72	Inosine triphosphate pyrophosphatase

0.78	GO:0009204	deoxyribonucleoside triphosphate catabolic process
0.56	GO:0009117	nucleotide metabolic process
0.52	GO:0009207	purine ribonucleoside triphosphate catabolic process
0.46	GO:0072523	purine-containing compound catabolic process
0.44	GO:1901136	carbohydrate derivative catabolic process
0.42	GO:0051276	chromosome organization
0.40	GO:0019693	ribose phosphate metabolic process

0.80	GO:0035529	NADH pyrophosphatase activity
0.72	GO:0047429	nucleoside-triphosphate diphosphatase activity
0.51	GO:0046872	metal ion binding
0.50	GO:1901265	nucleoside phosphate binding
0.49	GO:0036094	small molecule binding
0.46	GO:0042802	identical protein binding

0.47	GO:0005737	cytoplasm
0.41	GO:0005634	nucleus
0.34	GO:0019867	outer membrane

0.80	EC:3.6.1.9	GO:0035529
0.80	KEGG:R00103	GO:0035529

tr|T1FN79|T1FN79_HELRO
Uncharacterized protein
Search

RNF113A

0.60	Zinc finger protein 183

0.47	GO:0034247	snoRNA splicing
0.45	GO:0043484	regulation of RNA splicing
0.45	GO:0045292	mRNA cis splicing, via spliceosome
0.44	GO:0030182	neuron differentiation
0.34	GO:0002100	tRNA wobble adenosine to inosine editing
0.33	GO:1902476	chloride transmembrane transport

0.54	GO:0046872	metal ion binding
0.35	GO:0016874	ligase activity
0.34	GO:0008251	tRNA-specific adenosine deaminase activity
0.33	GO:0005247	voltage-gated chloride channel activity
0.33	GO:0005515	protein binding

0.45	GO:0005684	U2-type spliceosomal complex
0.30	GO:0031224	intrinsic component of membrane

0.35

GO:0016874

tr|T1FN80|T1FN80_HELRO
Uncharacterized protein
Search

0.63	Neurohemerythrin

0.39	GO:0015671	oxygen transport
0.34	GO:0046686	response to cadmium ion
0.32	GO:0007165	signal transduction

0.63	GO:0005506	iron ion binding
0.40	GO:0005344	oxygen carrier activity
0.33	GO:0004871	signal transducer activity

0.32	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

tr|T1FN81|T1FN81_HELRO
Uncharacterized protein
Search

MARCH5

0.92	Membrane associated ring-CH-type finger 5

0.56	GO:0090140	regulation of mitochondrial fission
0.56	GO:0090344	negative regulation of cell aging
0.55	GO:0051865	protein autoubiquitination
0.53	GO:0010822	positive regulation of mitochondrion organization
0.52	GO:0000209	protein polyubiquitination
0.51	GO:0070585	protein localization to mitochondrion
0.50	GO:0051094	positive regulation of developmental process

0.63	GO:0008270	zinc ion binding
0.51	GO:0016874	ligase activity
0.50	GO:0004842	ubiquitin-protein transferase activity
0.49	GO:0051020	GTPase binding

0.51	GO:0005741	mitochondrial outer membrane
0.49	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.51	EC:6	GO:0016874
0.50	KEGG:R03876	GO:0004842

tr|T1FN82|T1FN82_HELRO
Uncharacterized protein
Search

CNIH1

0.89	Putative er vesicle integral membrane protein involved in establishing cell polarity signaling

0.69	GO:0016192	vesicle-mediated transport
0.45	GO:0007310	oocyte dorsal/ventral axis specification
0.45	GO:0046843	dorsal appendage formation
0.44	GO:0007350	blastoderm segmentation
0.43	GO:0009952	anterior/posterior pattern specification
0.40	GO:0046907	intracellular transport
0.35	GO:0008314	gurken signaling pathway
0.34	GO:0000578	embryonic axis specification
0.34	GO:0051650	establishment of vesicle localization
0.34	GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation

0.34	GO:0003779	actin binding
0.34	GO:0071933	Arp2/3 complex binding
0.34	GO:0004672	protein kinase activity
0.33	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0016758	transferase activity, transferring hexosyl groups
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.42	GO:0005789	endoplasmic reticulum membrane
0.37	GO:0000139	Golgi membrane
0.35	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane
0.34	GO:0012507	ER to Golgi transport vesicle membrane
0.30	GO:0031224	intrinsic component of membrane

0.33	EC:2.4.1	GO:0016758
0.33	KEGG:R03876	GO:0004842

tr|T1FN83|T1FN83_HELRO
Uncharacterized protein
Search

PRKAR1A

0.45	cAMP-dependent protein kinase type I-alpha regulatory subunit

0.75	GO:0045859	regulation of protein kinase activity
0.51	GO:0046007	negative regulation of activated T cell proliferation
0.50	GO:0060038	cardiac muscle cell proliferation
0.49	GO:0016310	phosphorylation
0.49	GO:0045214	sarcomere organization
0.49	GO:0001707	mesoderm formation
0.48	GO:0033673	negative regulation of kinase activity
0.46	GO:0001933	negative regulation of protein phosphorylation
0.39	GO:0036211	protein modification process
0.37	GO:0044267	cellular protein metabolic process

0.85	GO:0008603	cAMP-dependent protein kinase regulator activity
0.83	GO:0030552	cAMP binding
0.51	GO:0016301	kinase activity
0.51	GO:0034236	protein kinase A catalytic subunit binding
0.50	GO:0004862	cAMP-dependent protein kinase inhibitor activity
0.47	GO:0031625	ubiquitin protein ligase binding
0.46	GO:0019904	protein domain specific binding
0.40	GO:0060089	molecular transducer activity
0.39	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.38	GO:0140096	catalytic activity, acting on a protein

0.84	GO:0005952	cAMP-dependent protein kinase complex
0.50	GO:0001772	immunological synapse
0.50	GO:0031588	nucleotide-activated protein kinase complex
0.49	GO:0044853	plasma membrane raft
0.49	GO:0031594	neuromuscular junction
0.48	GO:0005930	axoneme
0.35	GO:0097546	ciliary base
0.33	GO:0005829	cytosol

0.39

GO:0016773

tr|T1FN84|T1FN84_HELRO
Uncharacterized protein
Search

0.77	Gamma interferon inducible lysosomal thiol reductase GILT

0.45	GO:0055114	oxidation-reduction process
0.41	GO:0002376	immune system process
0.37	GO:0016567	protein ubiquitination
0.36	GO:0006508	proteolysis

0.56	GO:0016667	oxidoreductase activity, acting on a sulfur group of donors
0.40	GO:0016651	oxidoreductase activity, acting on NAD(P)H
0.37	GO:0070001	aspartic-type peptidase activity
0.37	GO:0004842	ubiquitin-protein transferase activity
0.36	GO:0004175	endopeptidase activity
0.36	GO:0008270	zinc ion binding
0.34	GO:0003676	nucleic acid binding

0.59	GO:0005764	lysosome
0.54	GO:0030054	cell junction
0.51	GO:0005829	cytosol
0.40	GO:0005576	extracellular region
0.35	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.56	EC:1.8	GO:0016667
0.37	KEGG:R03876	GO:0004842

tr|T1FN85|T1FN85_HELRO
Uncharacterized protein
Search

RAB2

0.63	Ras protein Rab 2

0.43	GO:0010256	endomembrane system organization
0.42	GO:0090390	phagosome acidification involved in apoptotic cell clearance
0.42	GO:0090325	regulation of locomotion involved in locomotory behavior
0.42	GO:1904811	positive regulation of dense core granule transport
0.42	GO:0090387	phagolysosome assembly involved in apoptotic cell clearance
0.41	GO:1901046	positive regulation of oviposition
0.40	GO:0002119	nematode larval development
0.40	GO:0021700	developmental maturation
0.39	GO:0040017	positive regulation of locomotion
0.37	GO:0040011	locomotion

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding
0.34	GO:0004767	sphingomyelin phosphodiesterase activity
0.32	GO:0046872	metal ion binding

0.47	GO:0005794	Golgi apparatus
0.41	GO:0043025	neuronal cell body
0.40	GO:0030424	axon
0.40	GO:0045335	phagocytic vesicle
0.40	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0031984	organelle subcompartment
0.39	GO:0005769	early endosome
0.39	GO:0005764	lysosome
0.36	GO:0098588	bounding membrane of organelle
0.34	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment

0.34	EC:3.1.4.12	GO:0004767
0.34	KEGG:R02541	GO:0004767

tr|T1FN86|T1FN86_HELRO
Uncharacterized protein
Search

0.88	Farnesyltransferase, CAAX box, beta

0.85	GO:0018343	protein farnesylation
0.76	GO:0042127	regulation of cell proliferation
0.46	GO:0042060	wound healing
0.44	GO:0048522	positive regulation of cellular process
0.43	GO:0007275	multicellular organism development
0.42	GO:0010557	positive regulation of macromolecule biosynthetic process
0.42	GO:0010628	positive regulation of gene expression
0.42	GO:0048523	negative regulation of cellular process
0.41	GO:0051173	positive regulation of nitrogen compound metabolic process
0.38	GO:1903506	regulation of nucleic acid-templated transcription

0.52	GO:0004660	protein farnesyltransferase activity
0.45	GO:0004311	farnesyltranstransferase activity
0.41	GO:0008270	zinc ion binding
0.36	GO:0019840	isoprenoid binding
0.35	GO:0042277	peptide binding
0.34	GO:0005515	protein binding
0.33	GO:0008144	drug binding

0.85	GO:0005965	protein farnesyltransferase complex
0.39	GO:0005875	microtubule associated complex
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.52	EC:2.5.1.58	GO:0004660
0.45	KEGG:R02061	GO:0004311

tr|T1FN87|T1FN87_HELRO
Uncharacterized protein
Search

0.43	AMP-dependent synthetase

0.36	GO:0001676	long-chain fatty acid metabolic process
0.35	GO:0009698	phenylpropanoid metabolic process
0.33	GO:0006313	transposition, DNA-mediated
0.33	GO:0055114	oxidation-reduction process

0.52	GO:0016874	ligase activity
0.34	GO:0004497	monooxygenase activity
0.33	GO:0004803	transposase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0008144	drug binding

0.30

GO:0031224

intrinsic component of membrane

0.52

GO:0016874

tr|T1FN88|T1FN88_HELRO
Uncharacterized protein
Search

0.38	Methylmalonate-semialdehyde dehydrogenase

0.53	GO:0055114	oxidation-reduction process
0.40	GO:0019859	thymine metabolic process
0.37	GO:0006573	valine metabolic process
0.35	GO:0050873	brown fat cell differentiation
0.34	GO:0006886	intracellular protein transport
0.34	GO:0016192	vesicle-mediated transport
0.34	GO:0045454	cell redox homeostasis
0.34	GO:0006208	pyrimidine nucleobase catabolic process
0.34	GO:0009083	branched-chain amino acid catabolic process
0.33	GO:0006091	generation of precursor metabolites and energy

0.80	GO:0004491	methylmalonate-semialdehyde dehydrogenase (acylating) activity
0.39	GO:0018478	malonate-semialdehyde dehydrogenase (acetylating) activity
0.36	GO:0000062	fatty-acyl-CoA binding
0.35	GO:0015035	protein disulfide oxidoreductase activity
0.34	GO:0009055	electron transfer activity
0.32	GO:0003677	DNA binding

0.35	GO:0005739	mitochondrion
0.33	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

0.80

EC:1.2.1.27

GO:0004491

tr|T1FN89|T1FN89_HELRO
Uncharacterized protein
Search

ILVBL

0.92	IlvB acetolactate synthase like

0.50

GO:0048701

embryonic cranial skeleton morphogenesis

0.73	GO:0030976	thiamine pyrophosphate binding
0.64	GO:0000287	magnesium ion binding
0.37	GO:0003984	acetolactate synthase activity
0.34	GO:0005515	protein binding

0.30

GO:0044425

membrane part

0.37

EC:2.2.1.6

GO:0003984

tr|T1FN90|T1FN90_HELRO
Uncharacterized protein
Search

UBE2K

0.70	Ubiquitin-conjugating enzyme E2Kb (UBC1 homolog, yeast)

0.43	GO:0000209	protein polyubiquitination
0.42	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0031625	ubiquitin protein ligase binding
0.42	GO:0061630	ubiquitin protein ligase activity

0.38	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm

tr|T1FN91|T1FN91_HELRO
Uncharacterized protein
Search

SNRNP40

0.91	Small nuclear ribonucleoprotein U5 subunit 40

0.45	GO:0008380	RNA splicing
0.36	GO:0006397	mRNA processing
0.34	GO:0006464	cellular protein modification process
0.33	GO:0016310	phosphorylation
0.33	GO:0032259	methylation

0.40	GO:0003723	RNA binding
0.37	GO:0016905	myosin heavy chain kinase activity
0.33	GO:0005515	protein binding
0.33	GO:0008168	methyltransferase activity

0.62	GO:0019013	viral nucleocapsid
0.58	GO:0030529	intracellular ribonucleoprotein complex
0.52	GO:0016607	nuclear speck
0.47	GO:0005829	cytosol
0.46	GO:0120114	Sm-like protein family complex
0.45	GO:1902494	catalytic complex
0.30	GO:0031224	intrinsic component of membrane

0.37

EC:2.7.11.7

GO:0016905

tr|T1FN92|T1FN92_HELRO
Pescadillo homolog
Search

PES1

0.76	Pescadillo

0.77	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.74	GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.48	GO:0007000	nucleolus organization
0.47	GO:0008283	cell proliferation
0.47	GO:0051726	regulation of cell cycle
0.44	GO:0031017	exocrine pancreas development
0.43	GO:0033365	protein localization to organelle
0.43	GO:0048709	oligodendrocyte differentiation
0.35	GO:0019915	lipid storage
0.33	GO:0009247	glycolipid biosynthetic process

0.67	GO:0043021	ribonucleoprotein complex binding
0.38	GO:0003723	RNA binding
0.35	GO:0050694	galactose 3-O-sulfotransferase activity
0.33	GO:0005515	protein binding

0.74	GO:0030687	preribosome, large subunit precursor
0.73	GO:0005730	nucleolus
0.70	GO:0005654	nucleoplasm
0.49	GO:0030686	90S preribosome
0.45	GO:0005694	chromosome
0.42	GO:0005829	cytosol
0.41	GO:0043234	protein complex
0.33	GO:0005794	Golgi apparatus
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:2.8.2

GO:0050694

tr|T1FN93|T1FN93_HELRO
Innexin
Search

INX

0.50

Innexin

0.58	GO:0006811	ion transport
0.37	GO:0016264	gap junction assembly
0.37	GO:0043051	regulation of pharyngeal pumping
0.37	GO:0018991	oviposition
0.36	GO:0055085	transmembrane transport
0.34	GO:0040011	locomotion
0.34	GO:0033227	dsRNA transport
0.34	GO:0072347	response to anesthetic
0.33	GO:0007186	G-protein coupled receptor signaling pathway

0.43	GO:0005243	gap junction channel activity
0.34	GO:0051032	nucleic acid transmembrane transporter activity
0.33	GO:0004930	G-protein coupled receptor activity

0.81	GO:0005921	gap junction
0.55	GO:0005886	plasma membrane
0.36	GO:0031252	cell leading edge
0.36	GO:0043005	neuron projection
0.35	GO:0120038	plasma membrane bounded cell projection part
0.30	GO:0016021	integral component of membrane

tr|T1FN94|T1FN94_HELRO
Uncharacterized protein
Search

EIF5

0.75	Eukaryotic translation initiation factor

0.72	GO:0006413	translational initiation
0.46	GO:0006446	regulation of translational initiation
0.37	GO:0090630	activation of GTPase activity
0.37	GO:0002181	cytoplasmic translation
0.36	GO:0022618	ribonucleoprotein complex assembly

0.73	GO:0003743	translation initiation factor activity
0.47	GO:0045296	cadherin binding
0.39	GO:0071074	eukaryotic initiation factor eIF2 binding
0.36	GO:0032550	purine ribonucleoside binding
0.36	GO:0019001	guanyl nucleotide binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0003924	GTPase activity

0.43	GO:0005829	cytosol
0.39	GO:0005886	plasma membrane
0.34	GO:0005634	nucleus

tr|T1FN95|T1FN95_HELRO
S-adenosylmethionine synthase
Search

0.54	S-adenosylmethionine synthase

0.78	GO:0006556	S-adenosylmethionine biosynthetic process
0.72	GO:0006730	one-carbon metabolic process
0.47	GO:0006555	methionine metabolic process
0.41	GO:0055013	cardiac muscle cell development
0.40	GO:0072358	cardiovascular system development
0.37	GO:0000098	sulfur amino acid catabolic process
0.37	GO:0051289	protein homotetramerization
0.36	GO:0009068	aspartate family amino acid catabolic process

0.79	GO:0004478	methionine adenosyltransferase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0046872	metal ion binding
0.36	GO:0042802	identical protein binding

0.37	GO:0005829	cytosol
0.35	GO:0048269	methionine adenosyltransferase complex
0.35	GO:0030446	hyphal cell wall
0.34	GO:0009986	cell surface
0.32	GO:0005886	plasma membrane

0.79

EC:2.5.1.6

GO:0004478

tr|T1FN96|T1FN96_HELRO
Uncharacterized protein
Search

HSPA9

0.48	Molecular chaperone DnaK

0.68	GO:0006457	protein folding
0.41	GO:0030097	hemopoiesis
0.41	GO:1902037	negative regulation of hematopoietic stem cell differentiation
0.40	GO:0045647	negative regulation of erythrocyte differentiation
0.39	GO:0006611	protein export from nucleus
0.39	GO:0034101	erythrocyte homeostasis
0.39	GO:0031101	fin regeneration
0.37	GO:0016226	iron-sulfur cluster assembly
0.37	GO:0030154	cell differentiation
0.34	GO:0010506	regulation of autophagy

0.71	GO:0051082	unfolded protein binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0031625	ubiquitin protein ligase binding
0.36	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.34	GO:0016887	ATPase activity

0.40	GO:0005759	mitochondrial matrix
0.39	GO:0043209	myelin sheath
0.38	GO:0009295	nucleoid
0.35	GO:0043232	intracellular non-membrane-bounded organelle
0.34	GO:0005615	extracellular space
0.30	GO:0016020	membrane

0.36

GO:0032440

tr|T1FN97|T1FN97_HELRO
SAGA-associated factor 11 homolog
Search

SGF11

0.73	SAGA-associated factor 11

0.78	GO:0016578	histone deubiquitination
0.69	GO:0045893	positive regulation of transcription, DNA-templated
0.55	GO:0006351	transcription, DNA-templated
0.42	GO:0051028	mRNA transport
0.39	GO:0015031	protein transport
0.36	GO:0071166	ribonucleoprotein complex localization
0.36	GO:0051169	nuclear transport
0.35	GO:0006405	RNA export from nucleus
0.35	GO:0003341	cilium movement
0.35	GO:0034613	cellular protein localization

0.72	GO:0003713	transcription coactivator activity
0.59	GO:0008270	zinc ion binding
0.34	GO:0005215	transporter activity
0.34	GO:0003777	microtubule motor activity
0.33	GO:0016887	ATPase activity
0.33	GO:0003677	DNA binding
0.33	GO:0016757	transferase activity, transferring glycosyl groups
0.32	GO:0005515	protein binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding

0.80	GO:0071819	DUBm complex
0.75	GO:0000124	SAGA complex
0.42	GO:0005643	nuclear pore
0.35	GO:0005737	cytoplasm
0.34	GO:0030286	dynein complex
0.34	GO:0044441	ciliary part
0.30	GO:0016020	membrane

0.33

EC:3.6.1.3

GO:0016887

tr|T1FN98|T1FN98_HELRO
Malate dehydrogenase
Search

0.44	NAD-dependent malate dehydrogenase

0.75	GO:0006108	malate metabolic process
0.70	GO:0006099	tricarboxylic acid cycle
0.60	GO:0005975	carbohydrate metabolic process
0.34	GO:0001300	chronological cell aging
0.34	GO:0001302	replicative cell aging
0.34	GO:0043043	peptide biosynthetic process
0.33	GO:0044267	cellular protein metabolic process
0.33	GO:0010467	gene expression
0.33	GO:0009059	macromolecule biosynthetic process

0.79	GO:0030060	L-malate dehydrogenase activity
0.34	GO:0003735	structural constituent of ribosome
0.33	GO:0003729	mRNA binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.34	GO:0005840	ribosome
0.33	GO:0005759	mitochondrial matrix

0.79

EC:1.1.1.37

GO:0030060

tr|T1FN99|T1FN99_HELRO
Uncharacterized protein
Search

0.69	cAMP-dependent protein kinase type I-alpha regulatory subunit

0.75	GO:0045859	regulation of protein kinase activity
0.53	GO:0046007	negative regulation of activated T cell proliferation
0.52	GO:0033673	negative regulation of kinase activity
0.52	GO:0060038	cardiac muscle cell proliferation
0.51	GO:0016310	phosphorylation
0.51	GO:0045214	sarcomere organization
0.51	GO:0001707	mesoderm formation
0.50	GO:0001933	negative regulation of protein phosphorylation
0.40	GO:0007611	learning or memory
0.39	GO:0051445	regulation of meiotic cell cycle

0.85	GO:0008603	cAMP-dependent protein kinase regulator activity
0.83	GO:0030552	cAMP binding
0.56	GO:0034236	protein kinase A catalytic subunit binding
0.55	GO:0004862	cAMP-dependent protein kinase inhibitor activity
0.53	GO:0016301	kinase activity
0.49	GO:0031625	ubiquitin protein ligase binding
0.48	GO:0019904	protein domain specific binding
0.34	GO:0042802	identical protein binding

0.84	GO:0005952	cAMP-dependent protein kinase complex
0.52	GO:0001772	immunological synapse
0.51	GO:0031588	nucleotide-activated protein kinase complex
0.51	GO:0044853	plasma membrane raft
0.50	GO:0031594	neuromuscular junction
0.50	GO:0005930	axoneme
0.35	GO:0097546	ciliary base
0.33	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

tr|T1FNA0|T1FNA0_HELRO
Uncharacterized protein
Search

0.88	Intermediate filament gliarin

0.62	GO:0005198	structural molecule activity
0.34	GO:0005515	protein binding

0.79	GO:0005882	intermediate filament
0.32	GO:0005737	cytoplasm

tr|T1FNA1|T1FNA1_HELRO
Uncharacterized protein
Search

0.38	Small GTP-binding protein Rab1

0.46	GO:0006888	ER to Golgi vesicle-mediated transport
0.39	GO:1990261	pre-mRNA catabolic process
0.39	GO:0048211	Golgi vesicle docking
0.39	GO:0035493	SNARE complex assembly
0.39	GO:0035494	SNARE complex disassembly
0.39	GO:0034498	early endosome to Golgi transport
0.39	GO:0061709	reticulophagy
0.39	GO:1900101	regulation of endoplasmic reticulum unfolded protein response
0.38	GO:0034497	protein localization to phagophore assembly site
0.38	GO:0032456	endocytic recycling

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0032561	guanyl ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0080115	myosin XI tail binding
0.44	GO:0030742	GTP-dependent protein binding
0.38	GO:0000149	SNARE binding
0.34	GO:0004767	sphingomyelin phosphodiesterase activity
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding

0.44	GO:0000139	Golgi membrane
0.42	GO:0005802	trans-Golgi network
0.39	GO:0005789	endoplasmic reticulum membrane
0.39	GO:0000407	phagophore assembly site
0.38	GO:0005801	cis-Golgi network
0.37	GO:0005795	Golgi stack
0.37	GO:0005886	plasma membrane
0.37	GO:0005829	cytosol
0.36	GO:0031410	cytoplasmic vesicle
0.34	GO:0005773	vacuole

0.34	EC:3.1.4.12	GO:0004767
0.34	KEGG:R02541	GO:0004767

tr|T1FNA2|T1FNA2_HELRO
Uncharacterized protein
Search

VAMP7

0.93	Vesicle associated membrane protein 7

0.68	GO:0016192	vesicle-mediated transport
0.54	GO:0002278	eosinophil activation involved in immune response
0.54	GO:0002447	eosinophil mediated immunity
0.53	GO:0090174	organelle membrane fusion
0.52	GO:1903595	positive regulation of histamine secretion by mast cell
0.52	GO:0007041	lysosomal transport
0.52	GO:0016050	vesicle organization
0.51	GO:0002283	neutrophil activation involved in immune response
0.51	GO:0002446	neutrophil mediated immunity
0.51	GO:1900483	regulation of protein targeting to vacuolar membrane

0.47	GO:0000149	SNARE binding
0.47	GO:0005484	SNAP receptor activity
0.32	GO:0003676	nucleic acid binding

0.52	GO:0031143	pseudopodium
0.52	GO:0031201	SNARE complex
0.52	GO:0035577	azurophil granule membrane
0.50	GO:0031091	platelet alpha granule
0.50	GO:0030027	lamellipodium
0.48	GO:0045335	phagocytic vesicle
0.47	GO:0005802	trans-Golgi network
0.46	GO:0045177	apical part of cell
0.46	GO:0043005	neuron projection
0.46	GO:0030133	transport vesicle

tr|T1FNA3|T1FNA3_HELRO
40S ribosomal protein SA
Search

0.59	Ribosomal protein rpsA (Fragment)

0.74	GO:0000028	ribosomal small subunit assembly
0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.41	GO:0007275	multicellular organism development
0.38	GO:0007155	cell adhesion
0.37	GO:0006407	rRNA export from nucleus
0.35	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.35	GO:0016072	rRNA metabolic process

0.64	GO:0003735	structural constituent of ribosome
0.44	GO:0005055	laminin receptor activity
0.41	GO:0043022	ribosome binding
0.40	GO:0043236	laminin binding

0.71	GO:0022627	cytosolic small ribosomal subunit
0.41	GO:0005634	nucleus
0.36	GO:0030686	90S preribosome
0.35	GO:0005886	plasma membrane
0.32	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

tr|T1FNA4|T1FNA4_HELRO
Uncharacterized protein
Search

RNF114

0.93	RING finger protein 166

0.51	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.50	GO:0000209	protein polyubiquitination
0.40	GO:0007283	spermatogenesis
0.38	GO:0030154	cell differentiation
0.38	GO:0007275	multicellular organism development
0.32	GO:0006508	proteolysis

0.52	GO:0046872	metal ion binding
0.52	GO:0031624	ubiquitin conjugating enzyme binding
0.48	GO:0061630	ubiquitin protein ligase activity
0.40	GO:0016874	ligase activity
0.35	GO:0003676	nucleic acid binding
0.33	GO:0004222	metalloendopeptidase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.48	GO:0005829	cytosol
0.42	GO:0005886	plasma membrane
0.36	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.40

GO:0016874

tr|T1FNA5|T1FNA5_HELRO
Uncharacterized protein
Search

CRNKL1

0.95	Crooked neck pre-mRNA splicing factor 1

0.63	GO:0006396	RNA processing
0.51	GO:0022618	ribonucleoprotein complex assembly
0.49	GO:0016071	mRNA metabolic process
0.35	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus
0.35	GO:0021987	cerebral cortex development
0.35	GO:1990830	cellular response to leukemia inhibitory factor

0.43	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.55	GO:0071013	catalytic step 2 spliceosome
0.52	GO:0005684	U2-type spliceosomal complex
0.48	GO:0071012	catalytic step 1 spliceosome
0.48	GO:0071011	precatalytic spliceosome
0.48	GO:0000974	Prp19 complex
0.47	GO:0071010	prespliceosome
0.47	GO:0071014	post-mRNA release spliceosomal complex
0.36	GO:0016607	nuclear speck
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|T1FNA6|T1FNA6_HELRO
Uncharacterized protein
Search

LDHD

0.50	Lactate dehydrogenase D

0.53	GO:0055114	oxidation-reduction process
0.35	GO:0006754	ATP biosynthetic process

0.66	GO:0050660	flavin adenine dinucleotide binding
0.65	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors
0.33	GO:0005515	protein binding

0.41	GO:0005739	mitochondrion
0.35	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.65

EC:1.1

GO:0016614

tr|T1FNA7|T1FNA7_HELRO
Probable tRNA N6-adenosine threonylcarbamoyltransferase
Search

OSGEP

0.83	Probable tRNA threonylcarbamoyladenosine biosynthesis protein OSGEP (Fragment)

0.75	GO:0002949	tRNA threonylcarbamoyladenosine modification
0.42	GO:0045948	positive regulation of translational initiation
0.34	GO:0006508	proteolysis
0.33	GO:0006351	transcription, DNA-templated
0.33	GO:0006355	regulation of transcription, DNA-templated
0.33	GO:0006281	DNA repair
0.33	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.32	GO:0055085	transmembrane transport

0.76	GO:0061711	N(6)-L-threonylcarbamoyladenine synthase
0.52	GO:0046872	metal ion binding
0.34	GO:0016787	hydrolase activity
0.34	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0016758	transferase activity, transferring hexosyl groups
0.33	GO:0005515	protein binding
0.32	GO:0003677	DNA binding

0.84	GO:0000408	EKC/KEOPS complex
0.59	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.45	GO:0031974	membrane-enclosed lumen
0.41	GO:0044446	intracellular organelle part
0.40	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.76

EC:2.3.1.234

GO:0061711

tr|T1FNA8|T1FNA8_HELRO
Uncharacterized protein
Search

0.72	GO:0006470	protein dephosphorylation
0.52	GO:0042347	negative regulation of NF-kappaB import into nucleus
0.49	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.48	GO:0010991	negative regulation of SMAD protein complex assembly
0.46	GO:0006499	N-terminal protein myristoylation
0.46	GO:0046827	positive regulation of protein export from nucleus
0.46	GO:0030514	negative regulation of BMP signaling pathway
0.46	GO:0030177	positive regulation of Wnt signaling pathway
0.45	GO:0071560	cellular response to transforming growth factor beta stimulus
0.44	GO:0016055	Wnt signaling pathway

0.77	GO:0004722	protein serine/threonine phosphatase activity
0.72	GO:0030145	manganese ion binding
0.64	GO:0000287	magnesium ion binding
0.47	GO:0070412	R-SMAD binding
0.33	GO:0004871	signal transducer activity

0.44	GO:0005829	cytosol
0.41	GO:0005634	nucleus
0.38	GO:0031974	membrane-enclosed lumen
0.38	GO:0005886	plasma membrane
0.37	GO:0043232	intracellular non-membrane-bounded organelle
0.36	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

tr|T1FNA9|T1FNA9_HELRO
Uncharacterized protein
Search

PRPF18

0.86	Pre-mRNA-processing factor 18

0.71	GO:0008380	RNA splicing
0.47	GO:0071048	nuclear retention of unspliced pre-mRNA at the site of transcription
0.42	GO:0006397	mRNA processing
0.42	GO:0022618	ribonucleoprotein complex assembly
0.34	GO:0032269	negative regulation of cellular protein metabolic process

0.46

GO:0000386

second spliceosomal transesterification activity

0.74	GO:0005681	spliceosomal complex
0.44	GO:0005682	U5 snRNP
0.44	GO:0046540	U4/U6 x U5 tri-snRNP complex
0.42	GO:0016607	nuclear speck
0.30	GO:0016020	membrane

tr|T1FNB0|T1FNB0_HELRO
Uncharacterized protein
Search

tr|T1FNB1|T1FNB1_HELRO
Uncharacterized protein
Search

0.83

Fascin

0.75	GO:0007015	actin filament organization
0.58	GO:0016477	cell migration
0.49	GO:0007163	establishment or maintenance of cell polarity
0.49	GO:0009887	animal organ morphogenesis
0.48	GO:0048468	cell development
0.48	GO:0007399	nervous system development
0.46	GO:0048568	embryonic organ development
0.46	GO:0002009	morphogenesis of an epithelium
0.46	GO:0007423	sensory organ development
0.44	GO:0007469	antennal development

0.80	GO:0030674	protein binding, bridging
0.78	GO:0051015	actin filament binding
0.36	GO:0045296	cadherin binding
0.34	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity
0.33	GO:0008144	drug binding

0.59	GO:0005856	cytoskeleton
0.47	GO:0043005	neuron projection
0.46	GO:0099512	supramolecular fiber
0.44	GO:0005737	cytoplasm
0.44	GO:0098858	actin-based cell projection
0.43	GO:0032421	stereocilium bundle
0.42	GO:0034399	nuclear periphery
0.42	GO:0043025	neuronal cell body
0.41	GO:0043234	protein complex
0.38	GO:0044393	microspike

0.34

EC:1.1.1.35

GO:0003857

tr|T1FNB2|T1FNB2_HELRO
Nucleoside diphosphate kinase
Search

0.46	Nucleoside diphosphate kinase B

0.79	GO:0006228	UTP biosynthetic process
0.79	GO:0006183	GTP biosynthetic process
0.75	GO:0046036	CTP metabolic process
0.70	GO:0006165	nucleoside diphosphate phosphorylation
0.44	GO:0007427	epithelial cell migration, open tracheal system
0.44	GO:0016334	establishment or maintenance of polarity of follicular epithelium
0.44	GO:0035152	regulation of tube architecture, open tracheal system
0.43	GO:0034332	adherens junction organization
0.42	GO:0018105	peptidyl-serine phosphorylation
0.42	GO:0046777	protein autophosphorylation

0.79	GO:0004550	nucleoside diphosphate kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0008017	microtubule binding
0.39	GO:0032550	purine ribonucleoside binding
0.38	GO:0019001	guanyl nucleotide binding
0.38	GO:0000287	magnesium ion binding
0.33	GO:0004673	protein histidine kinase activity
0.33	GO:0004519	endonuclease activity

0.44	GO:0005880	nuclear microtubule
0.36	GO:0001726	ruffle
0.36	GO:0030027	lamellipodium
0.34	GO:0005925	focal adhesion
0.34	GO:0005615	extracellular space
0.33	GO:0071944	cell periphery
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.79

EC:2.7.4.6

GO:0004550

tr|T1FNB3|T1FNB3_HELRO
Uncharacterized protein
Search

SMIM14

0.97	Small integral membrane protein 14

0.33

GO:0055114

oxidation-reduction process

0.34	GO:0051287	NAD binding
0.34	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
0.33	GO:0005515	protein binding

0.48	GO:0005783	endoplasmic reticulum
0.38	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.37	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:1.1.1

GO:0016616

tr|T1FNB4|T1FNB4_HELRO
Uncharacterized protein
Search

ILF2

0.94	Interleukin enhancer binding factor

0.73	GO:0006955	immune response
0.44	GO:0045893	positive regulation of transcription, DNA-templated
0.39	GO:0006351	transcription, DNA-templated
0.34	GO:0002446	neutrophil mediated immunity
0.34	GO:0043299	leukocyte degranulation
0.34	GO:0042119	neutrophil activation

0.59	GO:0003723	RNA binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0016740	transferase activity
0.38	GO:0003677	DNA binding
0.34	GO:0005515	protein binding

0.44	GO:0005730	nucleolus
0.41	GO:0005576	extracellular region
0.39	GO:0030529	intracellular ribonucleoprotein complex
0.35	GO:1904724	tertiary granule lumen
0.35	GO:0035580	specific granule lumen
0.35	GO:1904813	ficolin-1-rich granule lumen
0.30	GO:0031224	intrinsic component of membrane

0.51

GO:0016740

tr|T1FNB5|T1FNB5_HELRO
Uncharacterized protein
Search

0.55	Ribosomal protein rps4 (Fragment)

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.37	GO:0001522	pseudouridine synthesis
0.34	GO:0043009	chordate embryonic development
0.34	GO:0007420	brain development
0.33	GO:0030036	actin cytoskeleton organization

0.64	GO:0003735	structural constituent of ribosome
0.63	GO:0019843	rRNA binding
0.37	GO:0009982	pseudouridine synthase activity
0.35	GO:0003729	mRNA binding
0.34	GO:0000822	inositol hexakisphosphate binding
0.33	GO:0005515	protein binding

0.61	GO:0005840	ribosome
0.40	GO:0044445	cytosolic part
0.36	GO:0044446	intracellular organelle part
0.36	GO:0005773	vacuole
0.36	GO:0098805	whole membrane
0.36	GO:0098588	bounding membrane of organelle
0.35	GO:0005794	Golgi apparatus
0.34	GO:0009507	chloroplast
0.33	GO:0005615	extracellular space
0.33	GO:0005856	cytoskeleton

0.37

EC:5.4.99.12

GO:0009982

tr|T1FNB6|T1FNB6_HELRO
Uncharacterized protein
Search

CALU

0.79	Reticulocalbin calumenin dna supercoiling factor

0.38	GO:0007275	multicellular organism development
0.34	GO:0048678	response to axon injury
0.34	GO:0031099	regeneration
0.34	GO:0043687	post-translational protein modification
0.34	GO:0014070	response to organic cyclic compound
0.34	GO:0120036	plasma membrane bounded cell projection organization
0.34	GO:0048468	cell development
0.33	GO:0043086	negative regulation of catalytic activity
0.33	GO:0033554	cellular response to stress
0.32	GO:0055114	oxidation-reduction process

0.70	GO:0005509	calcium ion binding
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.34	GO:0005515	protein binding
0.33	GO:0004857	enzyme inhibitor activity

0.47	GO:0005783	endoplasmic reticulum
0.42	GO:0042470	melanosome
0.42	GO:0016528	sarcoplasm
0.39	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.39	GO:0005794	Golgi apparatus
0.38	GO:0031984	organelle subcompartment
0.38	GO:0043233	organelle lumen
0.38	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0032440

tr|T1FNB7|T1FNB7_HELRO
Uncharacterized protein
Search

ASH2L

0.88	ASH2 like histone lysine methyltransferase complex subunit

0.83	GO:0051568	histone H3-K4 methylation
0.52	GO:0043627	response to estrogen
0.49	GO:0008284	positive regulation of cell proliferation
0.46	GO:0045944	positive regulation of transcription by RNA polymerase II
0.44	GO:0060319	primitive erythrocyte differentiation
0.43	GO:0006974	cellular response to DNA damage stimulus
0.42	GO:0002244	hematopoietic progenitor cell differentiation
0.38	GO:0006351	transcription, DNA-templated
0.35	GO:1904837	beta-catenin-TCF complex assembly
0.35	GO:0045652	regulation of megakaryocyte differentiation

0.55	GO:0008168	methyltransferase activity
0.53	GO:1990188	euchromatin binding
0.50	GO:0008013	beta-catenin binding
0.49	GO:0044212	transcription regulatory region DNA binding
0.42	GO:0140096	catalytic activity, acting on a protein
0.41	GO:0046872	metal ion binding

0.81	GO:0048188	Set1C/COMPASS complex
0.51	GO:0044666	MLL3/4 complex
0.50	GO:0005719	nuclear euchromatin
0.49	GO:0071339	MLL1 complex
0.30	GO:0031224	intrinsic component of membrane

0.55

GO:0008168

tr|T1FNB8|T1FNB8_HELRO
Uncharacterized protein
Search

0.78	WD repeat domain phosphoinositide-interacting protein 2

0.76	GO:0006914	autophagy
0.74	GO:0007033	vacuole organization
0.66	GO:0070925	organelle assembly
0.38	GO:0061726	mitochondrion disassembly
0.38	GO:0006497	protein lipidation
0.38	GO:0034613	cellular protein localization
0.38	GO:0044090	positive regulation of vacuole organization
0.38	GO:0006624	vacuolar protein processing
0.37	GO:0045324	late endosome to vacuole transport
0.35	GO:0018410	C-terminal protein amino acid modification

0.81	GO:0032266	phosphatidylinositol-3-phosphate binding
0.79	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding
0.37	GO:0070273	phosphatidylinositol-4-phosphate binding
0.37	GO:0043130	ubiquitin binding

0.77	GO:0000407	phagophore assembly site
0.42	GO:0000329	fungal-type vacuole membrane
0.41	GO:0005768	endosome
0.39	GO:0019898	extrinsic component of membrane
0.38	GO:0061908	phagophore
0.38	GO:0005829	cytosol
0.36	GO:0061695	transferase complex, transferring phosphorus-containing groups
0.35	GO:0005776	autophagosome
0.34	GO:0044433	cytoplasmic vesicle part
0.34	GO:0005654	nucleoplasm

tr|T1FNB9|T1FNB9_HELRO
Uncharacterized protein
Search

AGXT2

0.78	Alanine-glyoxylate aminotransferase

0.54	GO:0019481	L-alanine catabolic process, by transamination
0.51	GO:0019265	glycine biosynthetic process, by transamination of glyoxylate
0.51	GO:0045429	positive regulation of nitric oxide biosynthetic process
0.50	GO:0009436	glyoxylate catabolic process
0.34	GO:0006419	alanyl-tRNA aminoacylation

0.69	GO:0008483	transaminase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.43	GO:0042802	identical protein binding
0.34	GO:0004813	alanine-tRNA ligase activity
0.34	GO:0008270	zinc ion binding
0.32	GO:0005524	ATP binding
0.32	GO:0003676	nucleic acid binding

0.43	GO:0005739	mitochondrion
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part

0.69

GO:0008483

tr|T1FNC0|T1FNC0_HELRO
Uncharacterized protein
Search

FAXDC2

0.93	fatty acid hydroxylase domain-containing protein 2

0.65	GO:0008610	lipid biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.33	GO:0009190	cyclic nucleotide biosynthetic process
0.32	GO:0035556	intracellular signal transduction

0.63	GO:0005506	iron ion binding
0.54	GO:0016491	oxidoreductase activity
0.33	GO:0016849	phosphorus-oxygen lyase activity
0.32	GO:1901265	nucleoside phosphate binding
0.32	GO:0036094	small molecule binding

0.41	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.54

GO:0016491

tr|T1FNC1|T1FNC1_HELRO
Uncharacterized protein
Search

SAR1A

0.78	GTP-binding protein SAR1 (inferred by orthology to a C. elegans protein)

0.69	GO:0006886	intracellular protein transport
0.68	GO:0016192	vesicle-mediated transport
0.50	GO:0051668	localization within membrane
0.48	GO:0016050	vesicle organization
0.45	GO:0034622	cellular macromolecular complex assembly
0.44	GO:0061024	membrane organization
0.37	GO:1901303	negative regulation of cargo loading into COPII-coated vesicle
0.37	GO:0009792	embryo development ending in birth or egg hatching
0.35	GO:0006796	phosphate-containing compound metabolic process
0.33	GO:0007186	G-protein coupled receptor signaling pathway

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0004427	inorganic diphosphatase activity
0.36	GO:0000287	magnesium ion binding
0.33	GO:0004930	G-protein coupled receptor activity
0.33	GO:0005515	protein binding

0.71	GO:0005794	Golgi apparatus
0.70	GO:0005783	endoplasmic reticulum
0.49	GO:0030127	COPII vesicle coat
0.44	GO:0031984	organelle subcompartment
0.36	GO:0016528	sarcoplasm
0.36	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.39	EC:3.6.1.1	GO:0004427
0.39	KEGG:R00004	GO:0004427

tr|T1FNC2|T1FNC2_HELRO
Uncharacterized protein
Search

0.45	Ribonuclease T2-A

0.70	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.39	GO:0006401	RNA catabolic process
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0016072	rRNA metabolic process

0.82	GO:0033897	ribonuclease T2 activity
0.59	GO:0003723	RNA binding
0.34	GO:0008847	Enterobacter ribonuclease activity

0.41	GO:0005788	endoplasmic reticulum lumen
0.40	GO:0005764	lysosome
0.39	GO:0005615	extracellular space
0.37	GO:0005775	vacuolar lumen
0.36	GO:1903561	extracellular vesicle
0.35	GO:0034774	secretory granule lumen
0.30	GO:0016020	membrane

0.82

EC:3.1.27.1

GO:0033897

tr|T1FNC3|T1FNC3_HELRO
Uncharacterized protein
Search

ABCF3

0.61	ATP-binding cassette sub-family F member

0.37	GO:0051607	defense response to virus
0.35	GO:0015716	organic phosphonate transport
0.35	GO:0015748	organophosphate ester transport
0.35	GO:0099133	ATP hydrolysis coupled anion transmembrane transport
0.32	GO:0006508	proteolysis

0.61	GO:0016887	ATPase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0045296	cadherin binding
0.35	GO:0015604	organic phosphonate transmembrane transporter activity
0.35	GO:0015605	organophosphate ester transmembrane transporter activity
0.34	GO:0008509	anion transmembrane transporter activity
0.34	GO:0015399	primary active transmembrane transporter activity
0.34	GO:0046872	metal ion binding

0.33	GO:0031012	extracellular matrix
0.30	GO:0016020	membrane

0.61

EC:3.6.1.3

GO:0016887

tr|T1FNC4|T1FNC4_HELRO
NADH-cytochrome b5 reductase
Search

0.63	NADH-cytochrome b5 reductase

0.53	GO:0055114	oxidation-reduction process
0.47	GO:0006809	nitric oxide biosynthetic process
0.45	GO:0042128	nitrate assimilation
0.40	GO:0016126	sterol biosynthetic process
0.36	GO:0001878	response to yeast
0.36	GO:0008203	cholesterol metabolic process
0.35	GO:1902653	secondary alcohol biosynthetic process
0.34	GO:0015701	bicarbonate transport
0.33	GO:0006508	proteolysis

0.74	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H
0.49	GO:0050464	nitrate reductase (NADPH) activity
0.45	GO:0030151	molybdenum ion binding
0.45	GO:0043546	molybdopterin cofactor binding
0.41	GO:0020037	heme binding
0.40	GO:0009703	nitrate reductase (NADH) activity
0.35	GO:0016208	AMP binding
0.35	GO:0043531	ADP binding
0.34	GO:0004252	serine-type endopeptidase activity
0.34	GO:0051287	NAD binding

0.41	GO:0005739	mitochondrion
0.37	GO:0005811	lipid droplet
0.36	GO:0005783	endoplasmic reticulum
0.36	GO:0005829	cytosol
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0031968	organelle outer membrane
0.35	GO:0031984	organelle subcompartment
0.34	GO:0019866	organelle inner membrane
0.34	GO:0070062	extracellular exosome
0.33	GO:0005634	nucleus

0.74

EC:1.6.2.2

GO:0004128

tr|T1FNC5|T1FNC5_HELRO
Eukaryotic translation initiation factor 3 subunit M
Search

EIF3M

0.73	Eukaryotic translation initiation factor 3 subunit M

0.70	GO:0006413	translational initiation
0.69	GO:0002181	cytoplasmic translation
0.68	GO:0006446	regulation of translational initiation
0.64	GO:0022618	ribonucleoprotein complex assembly
0.43	GO:2001272	positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis
0.42	GO:0097202	activation of cysteine-type endopeptidase activity
0.42	GO:0007291	sperm individualization
0.40	GO:0007030	Golgi organization
0.38	GO:0009306	protein secretion

0.71	GO:0003743	translation initiation factor activity
0.52	GO:0031369	translation initiation factor binding
0.42	GO:0089720	caspase binding
0.33	GO:0016757	transferase activity, transferring glycosyl groups

0.76	GO:0005852	eukaryotic translation initiation factor 3 complex
0.69	GO:0016282	eukaryotic 43S preinitiation complex
0.69	GO:0033290	eukaryotic 48S preinitiation complex
0.43	GO:0070865	investment cone
0.40	GO:0005794	Golgi apparatus
0.38	GO:0005829	cytosol

0.33

EC:2.4

GO:0016757

tr|T1FNC6|T1FNC6_HELRO
Aldehyde dehydrogenase
Search

ALDH3A2

0.42	Fatty aldehyde dehydrogenase

0.68	GO:0006081	cellular aldehyde metabolic process
0.52	GO:0055114	oxidation-reduction process
0.49	GO:0033306	phytol metabolic process
0.46	GO:0007422	peripheral nervous system development
0.45	GO:0008544	epidermis development
0.44	GO:0007417	central nervous system development
0.37	GO:0006714	sesquiterpenoid metabolic process
0.34	GO:0030148	sphingolipid biosynthetic process
0.34	GO:0009062	fatty acid catabolic process
0.34	GO:0000302	response to reactive oxygen species

0.79	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity
0.47	GO:0004029	aldehyde dehydrogenase (NAD) activity
0.47	GO:0046577	long-chain-alcohol oxidase activity
0.37	GO:0008106	alcohol dehydrogenase (NADP+) activity
0.35	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity

0.42	GO:0005783	endoplasmic reticulum
0.38	GO:0031090	organelle membrane
0.38	GO:0044429	mitochondrial part
0.38	GO:0031967	organelle envelope
0.37	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.37	GO:0005777	peroxisome
0.36	GO:0031984	organelle subcompartment
0.36	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.35	GO:0044438	microbody part

0.79

EC:1.2.1.5

GO:0004030

tr|T1FNC7|T1FNC7_HELRO
Superoxide dismutase [Cu-Zn]
Search

SOD1

0.52	Superoxide dismutase [Cu-Zn]

0.76	GO:0071450	cellular response to oxygen radical
0.76	GO:0000303	response to superoxide
0.75	GO:0006801	superoxide metabolic process
0.69	GO:0098869	cellular oxidant detoxification
0.53	GO:0055114	oxidation-reduction process
0.44	GO:0007569	cell aging
0.44	GO:0045541	negative regulation of cholesterol biosynthetic process
0.44	GO:0060087	relaxation of vascular smooth muscle
0.44	GO:1902177	positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
0.44	GO:0008090	retrograde axonal transport

0.77	GO:0004784	superoxide dismutase activity
0.54	GO:0046872	metal ion binding
0.44	GO:0030346	protein phosphatase 2B binding
0.43	GO:0048365	Rac GTPase binding
0.41	GO:0051087	chaperone binding
0.40	GO:0042802	identical protein binding
0.34	GO:0004601	peroxidase activity
0.33	GO:0046983	protein dimerization activity
0.32	GO:0003723	RNA binding
0.32	GO:0016787	hydrolase activity

0.43	GO:0032839	dendrite cytoplasm
0.43	GO:0005615	extracellular space
0.43	GO:1904115	axon cytoplasm
0.42	GO:0043209	myelin sheath
0.41	GO:0043025	neuronal cell body
0.41	GO:0005777	peroxisome
0.40	GO:0005829	cytosol
0.40	GO:0005634	nucleus
0.40	GO:0070013	intracellular organelle lumen
0.40	GO:0031012	extracellular matrix

0.77	EC:1.15.1.1	GO:0004784
0.34	KEGG:R03532	GO:0004601

tr|T1FNC8|T1FNC8_HELRO
Uncharacterized protein
Search

GUCD1

0.74	Guanylyl cyclase domain containing 1

0.50

GO:0005515

protein binding

0.30

GO:0044425

membrane part

tr|T1FNC9|T1FNC9_HELRO
Uncharacterized protein
Search

0.52	Cysteine protease

0.61	GO:0006508	proteolysis
0.43	GO:0044257	cellular protein catabolic process
0.41	GO:0010839	negative regulation of keratinocyte proliferation
0.41	GO:0046697	decidualization
0.41	GO:0031069	hair follicle morphogenesis
0.41	GO:2000249	regulation of actin cytoskeleton reorganization
0.41	GO:0097067	cellular response to thyroid hormone stimulus
0.40	GO:0030574	collagen catabolic process
0.39	GO:0002250	adaptive immune response
0.38	GO:0051604	protein maturation

0.72	GO:0008234	cysteine-type peptidase activity
0.43	GO:0042393	histone binding
0.42	GO:0097655	serpin family protein binding
0.42	GO:0004175	endopeptidase activity
0.40	GO:0001968	fibronectin binding
0.40	GO:0043394	proteoglycan binding
0.39	GO:0005518	collagen binding
0.38	GO:0004180	carboxypeptidase activity
0.37	GO:0030984	kininogen binding
0.35	GO:0042277	peptide binding

0.49	GO:0005764	lysosome
0.45	GO:0005615	extracellular space
0.39	GO:0031982	vesicle
0.38	GO:0005730	nucleolus
0.36	GO:0005775	vacuolar lumen
0.36	GO:0043204	perikaryon
0.36	GO:0005902	microvillus
0.35	GO:0009897	external side of plasma membrane
0.35	GO:0043230	extracellular organelle
0.35	GO:0045177	apical part of cell

0.72

GO:0008234

tr|T1FND0|T1FND0_HELRO
Uncharacterized protein
Search

0.70	Lateral Signaling Target

0.62	GO:0000278	mitotic cell cycle
0.55	GO:0015031	protein transport
0.45	GO:1990709	presynaptic active zone organization
0.45	GO:0001956	positive regulation of neurotransmitter secretion
0.44	GO:0030032	lamellipodium assembly
0.44	GO:0061640	cytoskeleton-dependent cytokinesis
0.43	GO:0071456	cellular response to hypoxia
0.43	GO:0000045	autophagosome assembly
0.42	GO:0006897	endocytosis
0.40	GO:0046907	intracellular transport

0.76	GO:0035091	phosphatidylinositol binding
0.34	GO:0043621	protein self-association
0.34	GO:0019902	phosphatase binding
0.33	GO:0051020	GTPase binding
0.33	GO:0016758	transferase activity, transferring hexosyl groups
0.33	GO:0003743	translation initiation factor activity

0.45	GO:0071212	subsynaptic reticulum
0.44	GO:0042734	presynaptic membrane
0.42	GO:0043025	neuronal cell body
0.42	GO:0048471	perinuclear region of cytoplasm
0.41	GO:0005938	cell cortex
0.39	GO:0031410	cytoplasmic vesicle
0.37	GO:0012506	vesicle membrane
0.35	GO:0044446	intracellular organelle part
0.34	GO:0016282	eukaryotic 43S preinitiation complex
0.34	GO:0033290	eukaryotic 48S preinitiation complex

0.33

EC:2.4.1

GO:0016758

tr|T1FND1|T1FND1_HELRO
Proteasome subunit beta type
Search

PSMB3

0.53	Proteasome subunit beta type

0.78	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.35	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation
0.35	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia
0.35	GO:0070498	interleukin-1-mediated signaling pathway
0.35	GO:0038061	NIK/NF-kappaB signaling

0.77	GO:0070003	threonine-type peptidase activity
0.65	GO:0004175	endopeptidase activity
0.34	GO:0005515	protein binding

0.82	GO:0019774	proteasome core complex, beta-subunit complex
0.59	GO:0005634	nucleus
0.47	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.35	GO:0043233	organelle lumen
0.34	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

tr|T1FND2|T1FND2_HELRO
Uncharacterized protein
Search

0.54	Receptor targeting protein Lin-7

0.76	GO:0099643	signal release from synapse
0.76	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.72	GO:0006887	exocytosis
0.70	GO:0006836	neurotransmitter transport
0.67	GO:0001505	regulation of neurotransmitter levels
0.64	GO:0051649	establishment of localization in cell
0.61	GO:0015031	protein transport
0.46	GO:0008582	regulation of synaptic growth at neuromuscular junction
0.45	GO:0007298	border follicle cell migration
0.44	GO:1903361	protein localization to basolateral plasma membrane

0.83	GO:0097016	L27 domain binding
0.34	GO:0004364	glutathione transferase activity
0.34	GO:0008092	cytoskeletal protein binding
0.33	GO:0016757	transferase activity, transferring glycosyl groups

0.82	GO:0097025	MPP7-DLG1-LIN7 complex
0.77	GO:0016323	basolateral plasma membrane
0.73	GO:0098793	presynapse
0.47	GO:0035003	subapical complex
0.44	GO:0045211	postsynaptic membrane
0.33	GO:0005622	intracellular
0.33	GO:1990904	ribonucleoprotein complex
0.30	GO:0016021	integral component of membrane

0.34

EC:2.5.1.18

GO:0004364

tr|T1FND3|T1FND3_HELRO
Uncharacterized protein
Search

DBR1

0.86	Lariat debranching enzyme A

0.70	GO:0006397	mRNA processing
0.51	GO:0000375	RNA splicing, via transesterification reactions
0.49	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.37	GO:0007124	pseudohyphal growth
0.37	GO:0032197	transposition, RNA-mediated
0.37	GO:0016074	snoRNA metabolic process
0.36	GO:0044265	cellular macromolecule catabolic process
0.35	GO:0034655	nucleobase-containing compound catabolic process
0.34	GO:0009793	embryo development ending in seed dormancy
0.34	GO:0051028	mRNA transport

0.61	GO:0016788	hydrolase activity, acting on ester bonds
0.45	GO:0140098	catalytic activity, acting on RNA
0.34	GO:0003723	RNA binding
0.33	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.33	GO:0046872	metal ion binding

0.45	GO:0005654	nucleoplasm
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.61

GO:0016788

tr|T1FND4|T1FND4_HELRO
Uncharacterized protein
Search

0.10	Ubiquinol-cytochrome c reductase core protein II

0.43	GO:0006508	proteolysis
0.42	GO:0006626	protein targeting to mitochondrion
0.40	GO:0051604	protein maturation
0.36	GO:0044267	cellular protein metabolic process

0.54	GO:0046872	metal ion binding
0.48	GO:0004222	metalloendopeptidase activity

0.42	GO:0005751	mitochondrial respiratory chain complex IV
0.42	GO:0005750	mitochondrial respiratory chain complex III
0.42	GO:0043209	myelin sheath
0.39	GO:0005654	nucleoplasm
0.30	GO:0016021	integral component of membrane

0.48

GO:0004222

tr|T1FND5|T1FND5_HELRO
Uncharacterized protein
Search

0.86	ATP synthase subunit O, mitochondrial

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.69	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.38	GO:0006839	mitochondrial transport
0.37	GO:0046907	intracellular transport
0.34	GO:0042407	cristae formation
0.33	GO:0018108	peptidyl-tyrosine phosphorylation
0.32	GO:0006415	translational termination

0.72	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism
0.35	GO:0005496	steroid binding
0.34	GO:0008144	drug binding
0.34	GO:0032403	protein complex binding
0.33	GO:0008553	proton-exporting ATPase activity, phosphorylative mechanism
0.33	GO:0004713	protein tyrosine kinase activity
0.32	GO:0003747	translation release factor activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.45	GO:0045259	proton-transporting ATP synthase complex
0.44	GO:0033178	proton-transporting two-sector ATPase complex, catalytic domain
0.40	GO:0005886	plasma membrane
0.39	GO:0098800	inner mitochondrial membrane protein complex
0.37	GO:0043209	myelin sheath
0.35	GO:0031012	extracellular matrix
0.35	GO:0070062	extracellular exosome
0.34	GO:0033177	proton-transporting two-sector ATPase complex, proton-transporting domain
0.33	GO:0005634	nucleus

0.33

EC:3.6.3.6

GO:0008553

tr|T1FND6|T1FND6_HELRO
Uncharacterized protein
Search

USP39

0.85	Ubiquitin specific peptidase 39

0.82	GO:0000245	spliceosomal complex assembly
0.76	GO:0016579	protein deubiquitination
0.47	GO:0048855	adenohypophysis morphogenesis
0.45	GO:1904888	cranial skeletal system development
0.44	GO:0043484	regulation of RNA splicing
0.35	GO:0051301	cell division
0.35	GO:0007049	cell cycle
0.34	GO:0006888	ER to Golgi vesicle-mediated transport
0.34	GO:0000413	protein peptidyl-prolyl isomerization
0.33	GO:0006886	intracellular protein transport

0.77	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.63	GO:0008270	zinc ion binding
0.34	GO:0070403	NAD+ binding
0.34	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003676	nucleic acid binding

0.46	GO:0005654	nucleoplasm
0.37	GO:0005681	spliceosomal complex
0.34	GO:0030127	COPII vesicle coat

0.77

GO:0036459

tr|T1FND7|T1FND7_HELRO
Uncharacterized protein
Search

0.18	kelch domain-containing protein 8A-like

0.55

GO:0016567

protein ubiquitination

0.55

GO:0004842

ubiquitin-protein transferase activity

0.76	GO:0016235	aggresome
0.72	GO:0043025	neuronal cell body
0.69	GO:0043005	neuron projection
0.66	GO:0015629	actin cytoskeleton
0.63	GO:0005783	endoplasmic reticulum
0.62	GO:0005829	cytosol
0.61	GO:0031463	Cul3-RING ubiquitin ligase complex

0.55

GO:0004842

tr|T1FND8|T1FND8_HELRO
Uncharacterized protein
Search

0.42	Mitochondrial hydroxyacyl-coenzyme a dehydrogenase

0.69	GO:0006631	fatty acid metabolic process
0.53	GO:0055114	oxidation-reduction process
0.38	GO:0032958	inositol phosphate biosynthetic process
0.35	GO:0016310	phosphorylation
0.34	GO:0044242	cellular lipid catabolic process
0.34	GO:0030258	lipid modification
0.34	GO:0072329	monocarboxylic acid catabolic process

0.76	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity
0.74	GO:0070403	NAD+ binding
0.37	GO:0008691	3-hydroxybutyryl-CoA dehydrogenase activity
0.35	GO:0016301	kinase activity
0.32	GO:0016853	isomerase activity
0.32	GO:0046872	metal ion binding

0.38	GO:0005654	nucleoplasm
0.37	GO:0044429	mitochondrial part
0.36	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

0.76

EC:1.1.1.35

GO:0003857

tr|T1FND9|T1FND9_HELRO
Uncharacterized protein
Search

tr|T1FNE0|T1FNE0_HELRO
Uncharacterized protein
Search

tr|T1FNE1|T1FNE1_HELRO
Uncharacterized protein
Search

SAMM50

0.92	Sorting and assembly machinery component 50

0.51	GO:0042407	cristae formation
0.49	GO:0045040	protein import into mitochondrial outer membrane
0.48	GO:0033108	mitochondrial respiratory chain complex assembly
0.34	GO:0001889	liver development
0.32	GO:0006629	lipid metabolic process

0.34	GO:0005515	protein binding
0.33	GO:0005509	calcium ion binding

0.66	GO:0019867	outer membrane
0.46	GO:0098805	whole membrane
0.46	GO:0098588	bounding membrane of organelle
0.45	GO:0098798	mitochondrial protein complex
0.45	GO:0044455	mitochondrial membrane part
0.41	GO:0098796	membrane protein complex
0.41	GO:0019866	organelle inner membrane
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

tr|T1FNE2|T1FNE2_HELRO
Annexin
Search

0.60

Annexin

0.34	GO:0001778	plasma membrane repair
0.33	GO:0009846	pollen germination
0.33	GO:0009860	pollen tube growth
0.33	GO:0009639	response to red or far red light
0.33	GO:0009555	pollen development
0.33	GO:0009414	response to water deprivation
0.33	GO:0009651	response to salt stress
0.33	GO:0055114	oxidation-reduction process
0.33	GO:0009409	response to cold
0.32	GO:0009408	response to heat

0.81	GO:0005544	calcium-dependent phospholipid binding
0.70	GO:0005509	calcium ion binding
0.35	GO:0004488	methylenetetrahydrofolate dehydrogenase (NADP+) activity
0.32	GO:0051015	actin filament binding

0.30

GO:0031224

intrinsic component of membrane

0.35	EC:1.5.1.5	GO:0004488
0.35	KEGG:R01220	GO:0004488

tr|T1FNE3|T1FNE3_HELRO
Tubulin alpha chain
Search

0.53	Tubulin alpha chain

0.72	GO:0007017	microtubule-based process
0.71	GO:0007010	cytoskeleton organization
0.36	GO:0033198	response to ATP
0.36	GO:0035590	purinergic nucleotide receptor signaling pathway
0.35	GO:0060079	excitatory postsynaptic potential
0.34	GO:0098655	cation transmembrane transport

0.77	GO:0005200	structural constituent of cytoskeleton
0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.36	GO:0004931	extracellularly ATP-gated cation channel activity
0.36	GO:0016502	nucleotide receptor activity
0.36	GO:0035586	purinergic receptor activity
0.33	GO:0005515	protein binding

0.73	GO:0005874	microtubule
0.48	GO:0005737	cytoplasm
0.38	GO:0036064	ciliary basal body
0.35	GO:0098794	postsynapse
0.34	GO:0005887	integral component of plasma membrane
0.34	GO:0005634	nucleus

tr|T1FNE4|T1FNE4_HELRO
Uncharacterized protein
Search

0.47	Mechanosensory protein 2

0.42

GO:0097206

nephrocyte filtration

0.33

GO:0005515

protein binding

0.45	GO:0005887	integral component of plasma membrane
0.35	GO:0005917	nephrocyte diaphragm

tr|T1FNE5|T1FNE5_HELRO
40S ribosomal protein S3a
Search

tr|T1FNE6|T1FNE6_HELRO
Uncharacterized protein
Search

tr|T1FNE7|T1FNE7_HELRO
Uncharacterized protein
Search

tr|T1FNE8|T1FNE8_HELRO
Uncharacterized protein
Search

0.45	Fibrinolytic enzyme, isozyme C

0.61	GO:0006508	proteolysis
0.51	GO:0042730	fibrinolysis
0.49	GO:0007596	blood coagulation
0.48	GO:0048771	tissue remodeling
0.44	GO:0052213	interaction with symbiont via secreted substance involved in symbiotic interaction
0.44	GO:0006898	receptor-mediated endocytosis
0.44	GO:0052212	modification of morphology or physiology of other organism via secreted substance involved in symbiotic interaction
0.43	GO:0051919	positive regulation of fibrinolysis
0.43	GO:0060707	trophoblast giant cell differentiation
0.42	GO:0060716	labyrinthine layer blood vessel development

0.69	GO:0004252	serine-type endopeptidase activity
0.47	GO:0005044	scavenger receptor activity
0.44	GO:1904854	proteasome core complex binding
0.43	GO:1990405	protein antigen binding
0.43	GO:0034185	apolipoprotein binding
0.42	GO:0019900	kinase binding
0.40	GO:0019904	protein domain specific binding
0.40	GO:0051087	chaperone binding
0.39	GO:0005102	receptor binding
0.37	GO:0005509	calcium ion binding

0.47	GO:0005576	extracellular region
0.42	GO:0031232	extrinsic component of external side of plasma membrane
0.38	GO:0044218	other organism cell membrane
0.34	GO:0031093	platelet alpha granule lumen
0.33	GO:1990777	lipoprotein particle
0.32	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.69

GO:0004252

tr|T1FNE9|T1FNE9_HELRO
Uncharacterized protein
Search

0.46	Fibrinolytic protein III

0.61	GO:0006508	proteolysis
0.43	GO:0006898	receptor-mediated endocytosis
0.41	GO:0006883	cellular sodium ion homeostasis
0.40	GO:0007605	sensory perception of sound
0.37	GO:0065009	regulation of molecular function
0.37	GO:0008203	cholesterol metabolic process
0.36	GO:0007596	blood coagulation
0.34	GO:0048012	hepatocyte growth factor receptor signaling pathway
0.34	GO:0007586	digestion
0.33	GO:0061138	morphogenesis of a branching epithelium

0.69	GO:0004252	serine-type endopeptidase activity
0.46	GO:0005044	scavenger receptor activity
0.40	GO:0017080	sodium channel regulator activity
0.35	GO:0005509	calcium ion binding
0.32	GO:0008483	transaminase activity
0.32	GO:0030170	pyridoxal phosphate binding
0.32	GO:0016301	kinase activity

0.39	GO:0043025	neuronal cell body
0.38	GO:0005615	extracellular space
0.38	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0046658	anchored component of plasma membrane
0.35	GO:0001669	acrosomal vesicle
0.34	GO:0019897	extrinsic component of plasma membrane
0.30	GO:0016021	integral component of membrane

0.69

GO:0004252

tr|T1FNF0|T1FNF0_HELRO
Uncharacterized protein
Search

0.44	Serine-type enodpeptidase

0.61	GO:0006508	proteolysis
0.50	GO:0006898	receptor-mediated endocytosis
0.47	GO:0002542	Factor XII activation
0.47	GO:0051919	positive regulation of fibrinolysis
0.46	GO:0010756	positive regulation of plasminogen activation
0.45	GO:0030194	positive regulation of blood coagulation
0.45	GO:0007596	blood coagulation
0.44	GO:0051788	response to misfolded protein
0.42	GO:0051604	protein maturation
0.38	GO:0042730	fibrinolysis

0.69	GO:0004252	serine-type endopeptidase activity
0.54	GO:0005044	scavenger receptor activity
0.46	GO:0005509	calcium ion binding
0.34	GO:0051787	misfolded protein binding
0.34	GO:0016301	kinase activity
0.34	GO:0070008	serine-type exopeptidase activity
0.33	GO:0005216	ion channel activity

0.47	GO:0005615	extracellular space
0.35	GO:0097209	epidermal lamellar body
0.34	GO:0005886	plasma membrane
0.34	GO:0005578	proteinaceous extracellular matrix
0.34	GO:1903561	extracellular vesicle
0.30	GO:0016021	integral component of membrane

0.69

GO:0004252

tr|T1FNF1|T1FNF1_HELRO
Lipase
Search

0.44	lipase member K

0.61	GO:0016042	lipid catabolic process
0.35	GO:0048513	animal organ development
0.35	GO:0048873	homeostasis of number of cells within a tissue
0.35	GO:0048869	cellular developmental process
0.35	GO:0048771	tissue remodeling
0.35	GO:0001816	cytokine production
0.35	GO:0060541	respiratory system development
0.34	GO:0006954	inflammatory response
0.34	GO:0008283	cell proliferation
0.34	GO:0008544	epidermis development

0.58

GO:0016788

hydrolase activity, acting on ester bonds

0.35	GO:0001650	fibrillar center
0.34	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.58

GO:0016788

tr|T1FNF2|T1FNF2_HELRO
Uncharacterized protein
Search

0.44	Serine threonine kinase

0.63	GO:0006468	protein phosphorylation
0.55	GO:1990872	negative regulation of sterol import by negative regulation of transcription from RNA polymerase II promoter
0.55	GO:0042981	regulation of apoptotic process
0.55	GO:0007232	osmosensory signaling pathway via Sho1 osmosensor
0.54	GO:0007121	bipolar cellular bud site selection
0.54	GO:0035376	sterol import
0.54	GO:0001402	signal transduction involved in filamentous growth
0.53	GO:0034063	stress granule assembly
0.53	GO:0007118	budding cell apical bud growth
0.53	GO:0007124	pseudohyphal growth

0.68	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0032555	purine ribonucleotide binding
0.53	GO:0035173	histone kinase activity
0.49	GO:0005057	signal transducer activity, downstream of receptor
0.40	GO:0048365	Rac GTPase binding
0.35	GO:0030296	protein tyrosine kinase activator activity
0.34	GO:0045296	cadherin binding

0.52	GO:0000131	incipient cellular bud site
0.51	GO:0043332	mating projection tip
0.43	GO:0005634	nucleus
0.39	GO:0071521	Cdc42 GTPase complex
0.39	GO:0120105	actomyosin contractile ring, intermediate layer
0.38	GO:0051286	cell tip
0.38	GO:0005876	spindle microtubule
0.33	GO:0005829	cytosol

0.68

GO:0004674

tr|T1FNF3|T1FNF3_HELRO
Uncharacterized protein
Search

tr|T1FNF4|T1FNF4_HELRO
Uncharacterized protein
Search

STX16

0.87	STX16-NPEPL1 readthrough (NMD candidate)

0.69	GO:0016192	vesicle-mediated transport
0.68	GO:0006886	intracellular protein transport
0.67	GO:0061025	membrane fusion
0.44	GO:0090161	Golgi ribbon formation
0.44	GO:0048284	organelle fusion
0.43	GO:0016050	vesicle organization
0.43	GO:0140056	organelle localization by membrane tethering
0.41	GO:0016482	cytosolic transport
0.41	GO:0016197	endosomal transport
0.39	GO:0039023	pronephric duct morphogenesis

0.78	GO:0005484	SNAP receptor activity
0.47	GO:0000149	SNARE binding
0.34	GO:0004197	cysteine-type endopeptidase activity
0.34	GO:0008235	metalloexopeptidase activity
0.34	GO:0030145	manganese ion binding
0.34	GO:0004177	aminopeptidase activity
0.33	GO:0008270	zinc ion binding

0.70	GO:0031201	SNARE complex
0.45	GO:0012505	endomembrane system
0.41	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0043231	intracellular membrane-bounded organelle
0.39	GO:0005829	cytosol
0.39	GO:0031984	organelle subcompartment
0.36	GO:0005925	focal adhesion
0.35	GO:0098588	bounding membrane of organelle
0.30	GO:0016021	integral component of membrane

0.34

EC:3.4.22

GO:0004197

tr|T1FNF5|T1FNF5_HELRO
Uncharacterized protein
Search

0.52	CAP, cysteine-rich secretory protein, antigen 5

0.48	GO:0060325	face morphogenesis
0.46	GO:0030198	extracellular matrix organization
0.36	GO:0048513	animal organ development
0.35	GO:0060021	palate development
0.35	GO:1904888	cranial skeletal system development
0.35	GO:0048706	embryonic skeletal system development
0.35	GO:0061448	connective tissue development
0.35	GO:0060541	respiratory system development
0.34	GO:0048598	embryonic morphogenesis
0.34	GO:0048729	tissue morphogenesis

0.46	GO:0008201	heparin binding
0.34	GO:0005246	calcium channel regulator activity
0.34	GO:0008233	peptidase activity
0.33	GO:0008061	chitin binding
0.33	GO:0050660	flavin adenine dinucleotide binding
0.32	GO:0046872	metal ion binding

0.66	GO:0005576	extracellular region
0.44	GO:0030133	transport vesicle
0.34	GO:1904813	ficolin-1-rich granule lumen
0.34	GO:0034774	secretory granule lumen
0.32	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016020	membrane

0.34

GO:0008233

tr|T1FNF6|T1FNF6_HELRO
Uncharacterized protein
Search

SLC2A1

0.64	Glucose transporter type

0.60	GO:0008643	carbohydrate transport
0.55	GO:0055085	transmembrane transport
0.45	GO:0070837	dehydroascorbic acid transport
0.41	GO:0042149	cellular response to glucose starvation
0.39	GO:0048085	adult chitin-containing cuticle pigmentation
0.39	GO:0090276	regulation of peptide hormone secretion
0.39	GO:0071332	cellular response to fructose stimulus
0.39	GO:0046887	positive regulation of hormone secretion
0.38	GO:0002793	positive regulation of peptide secretion
0.38	GO:0006461	protein complex assembly

0.57	GO:0022857	transmembrane transporter activity
0.42	GO:0043621	protein self-association
0.39	GO:0042802	identical protein binding
0.35	GO:0070061	fructose binding
0.35	GO:0019900	kinase binding
0.33	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.32	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.31	GO:0008168	methyltransferase activity
0.31	GO:0003676	nucleic acid binding

0.44	GO:0016324	apical plasma membrane
0.42	GO:0001939	female pronucleus
0.41	GO:0030864	cortical actin cytoskeleton
0.40	GO:0030496	midbody
0.40	GO:0016323	basolateral plasma membrane
0.40	GO:0098857	membrane microdomain
0.39	GO:0031982	vesicle
0.39	GO:0005887	integral component of plasma membrane
0.38	GO:0005829	cytosol
0.38	GO:0005911	cell-cell junction

0.33

GO:0032440

tr|T1FNF7|T1FNF7_HELRO
Uncharacterized protein
Search

RAD23A

0.90	UV excision repair protein RAD23 like protein A

0.77	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.73	GO:0006289	nucleotide-excision repair
0.53	GO:0045070	positive regulation of viral genome replication
0.52	GO:0031648	protein destabilization
0.51	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.49	GO:0045787	positive regulation of cell cycle
0.34	GO:0016579	protein deubiquitination
0.33	GO:0051704	multi-organism process
0.33	GO:0006468	protein phosphorylation
0.33	GO:0043043	peptide biosynthetic process

0.73	GO:0003684	damaged DNA binding
0.53	GO:1990381	ubiquitin-specific protease binding
0.52	GO:0031593	polyubiquitin modification-dependent protein binding
0.49	GO:0019900	kinase binding
0.34	GO:0003697	single-stranded DNA binding
0.33	GO:0003735	structural constituent of ribosome
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005634	nucleus
0.48	GO:0005815	microtubule organizing center
0.46	GO:0005829	cytosol
0.45	GO:0031974	membrane-enclosed lumen
0.42	GO:0043234	protein complex
0.37	GO:1905369	endopeptidase complex
0.33	GO:0005840	ribosome
0.33	GO:1990391	DNA repair complex

tr|T1FNF8|T1FNF8_HELRO
Uncharacterized protein
Search

0.78	Translocase of outer mitochondrial membrane 40 homolog

0.82	GO:0030150	protein import into mitochondrial matrix
0.38	GO:0071456	cellular response to hypoxia
0.34	GO:0051204	protein insertion into mitochondrial membrane
0.34	GO:0016236	macroautophagy
0.34	GO:0006811	ion transport
0.34	GO:0006468	protein phosphorylation
0.34	GO:0043065	positive regulation of apoptotic process

0.74	GO:0008320	protein transmembrane transporter activity
0.36	GO:0015288	porin activity
0.35	GO:0070678	preprotein binding
0.34	GO:0044877	macromolecular complex binding
0.34	GO:0004674	protein serine/threonine kinase activity
0.33	GO:0005261	cation channel activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.78	GO:0005741	mitochondrial outer membrane
0.46	GO:0098798	mitochondrial protein complex
0.46	GO:0044455	mitochondrial membrane part
0.43	GO:0031301	integral component of organelle membrane
0.42	GO:0098796	membrane protein complex
0.41	GO:0005829	cytosol
0.40	GO:0019866	organelle inner membrane
0.37	GO:0042719	mitochondrial intermembrane space protein transporter complex
0.35	GO:0070062	extracellular exosome

0.34

GO:0004674

tr|T1FNF9|T1FNF9_HELRO
Uncharacterized protein
Search

GINS3

0.71	DNA replication complex GINS protein PSF3

0.66	GO:0006260	DNA replication
0.40	GO:1903047	mitotic cell cycle process
0.37	GO:0000727	double-strand break repair via break-induced replication

0.61	GO:0005634	nucleus
0.49	GO:0031974	membrane-enclosed lumen
0.44	GO:0044446	intracellular organelle part
0.38	GO:0005694	chromosome
0.35	GO:0032993	protein-DNA complex
0.34	GO:0043234	protein complex

tr|T1FNG0|T1FNG0_HELRO
Uncharacterized protein
Search

RAB24

0.93	Max dimerization protein 3

0.35	GO:0006914	autophagy
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0015031	protein transport
0.34	GO:0060627	regulation of vesicle-mediated transport
0.33	GO:0034389	lipid particle organization
0.33	GO:0051641	cellular localization
0.33	GO:0048193	Golgi vesicle transport
0.33	GO:0140029	exocytic process
0.33	GO:0022406	membrane docking
0.33	GO:1903530	regulation of secretion by cell

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0032561	guanyl ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding
0.33	GO:0004767	sphingomyelin phosphodiesterase activity
0.33	GO:0051213	dioxygenase activity

0.54	GO:0005776	autophagosome
0.42	GO:0005739	mitochondrion
0.35	GO:0012505	endomembrane system
0.34	GO:0005829	cytosol
0.34	GO:0098588	bounding membrane of organelle
0.34	GO:0031410	cytoplasmic vesicle
0.34	GO:0012506	vesicle membrane
0.33	GO:0098805	whole membrane
0.33	GO:0044446	intracellular organelle part
0.33	GO:0005886	plasma membrane

0.33	EC:3.1.4.12	GO:0004767
0.33	KEGG:R02541	GO:0004767

tr|T1FNG1|T1FNG1_HELRO
Uncharacterized protein
Search

WDR45B

0.89	WD repeat domain phosphoinositide-interacting protein 3

0.83	GO:0034497	protein localization to phagophore assembly site
0.81	GO:0044804	autophagy of nucleus
0.81	GO:0000422	autophagy of mitochondrion
0.74	GO:0006497	protein lipidation

0.81	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding
0.79	GO:0032266	phosphatidylinositol-3-phosphate binding
0.46	GO:0003924	GTPase activity
0.45	GO:0032550	purine ribonucleoside binding
0.45	GO:0019001	guanyl nucleotide binding
0.40	GO:0032555	purine ribonucleotide binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding

0.80	GO:0034045	phagophore assembly site membrane
0.71	GO:0019898	extrinsic component of membrane
0.65	GO:0005829	cytosol

tr|T1FNG2|T1FNG2_HELRO
Uncharacterized protein
Search

0.89	Transmembrane protein 120B

0.56	GO:0045444	fat cell differentiation
0.55	GO:0051291	protein heterooligomerization
0.46	GO:0051260	protein homooligomerization

0.33

GO:0005515

protein binding

0.50	GO:0005637	nuclear inner membrane
0.30	GO:0044425	membrane part

tr|T1FNG3|T1FNG3_HELRO
Uncharacterized protein
Search

MRPL2

0.94	Mitochondrial ribosomal protein L2

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.34	GO:0043624	cellular protein complex disassembly
0.33	GO:0000226	microtubule cytoskeleton organization
0.33	GO:0043632	modification-dependent macromolecule catabolic process
0.33	GO:0030163	protein catabolic process
0.32	GO:0006508	proteolysis
0.32	GO:0036211	protein modification process

0.64	GO:0003735	structural constituent of ribosome
0.40	GO:0003723	RNA binding
0.35	GO:0016740	transferase activity
0.33	GO:0031625	ubiquitin protein ligase binding

0.61	GO:0005840	ribosome
0.49	GO:0005759	mitochondrial matrix
0.34	GO:1990393	3M complex
0.34	GO:0031467	Cul7-RING ubiquitin ligase complex
0.34	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0031966	mitochondrial membrane
0.33	GO:0019866	organelle inner membrane

0.35

GO:0016740

tr|T1FNG4|T1FNG4_HELRO
Uncharacterized protein
Search

MED8

0.93	Mediator of RNA polymerase II transcription subunit 8-B

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.58	GO:0006351	transcription, DNA-templated
0.40	GO:0016567	protein ubiquitination
0.34	GO:0007186	G-protein coupled receptor signaling pathway

0.79	GO:0001104	RNA polymerase II transcription cofactor activity
0.34	GO:0005515	protein binding
0.34	GO:0004930	G-protein coupled receptor activity

0.77	GO:0016592	mediator complex
0.30	GO:0031224	intrinsic component of membrane

tr|T1FNG5|T1FNG5_HELRO
Uncharacterized protein
Search

0.43	Glycine C-acetyltransferase

0.79	GO:0006567	threonine catabolic process
0.49	GO:0009058	biosynthetic process
0.41	GO:0006544	glycine metabolic process
0.40	GO:0042737	drug catabolic process

0.83	GO:0008890	glycine C-acetyltransferase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.50	GO:0016874	ligase activity
0.33	GO:0008483	transaminase activity

0.41	GO:0016607	nuclear speck
0.37	GO:0031966	mitochondrial membrane
0.37	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.83	EC:2.3.1.29	GO:0008890
0.83	KEGG:R00371	GO:0008890

tr|T1FNG6|T1FNG6_HELRO
Uncharacterized protein
Search

0.80	Guanine nucleotide-binding protein beta subunit

0.65	GO:1903208	negative regulation of hydrogen peroxide-induced neuron death
0.65	GO:0033123	positive regulation of purine nucleotide catabolic process
0.65	GO:0030807	positive regulation of cyclic nucleotide catabolic process
0.65	GO:0030820	regulation of cAMP catabolic process
0.65	GO:2000543	positive regulation of gastrulation
0.65	GO:0051343	positive regulation of cyclic-nucleotide phosphodiesterase activity
0.63	GO:0032464	positive regulation of protein homooligomerization
0.63	GO:0051901	positive regulation of mitochondrial depolarization
0.63	GO:0050765	negative regulation of phagocytosis
0.62	GO:0042998	positive regulation of Golgi to plasma membrane protein transport

0.64	GO:0030292	protein tyrosine kinase inhibitor activity
0.62	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process
0.62	GO:0042169	SH2 domain binding
0.61	GO:0005080	protein kinase C binding
0.60	GO:0030971	receptor tyrosine kinase binding
0.58	GO:0035591	signaling adaptor activity
0.58	GO:0019903	protein phosphatase binding
0.58	GO:0030332	cyclin binding
0.57	GO:0045296	cadherin binding
0.54	GO:0043022	ribosome binding

0.64	GO:1990630	IRE1-RACK1-PP2A complex
0.62	GO:0001891	phagocytic cup
0.59	GO:0030496	midbody
0.57	GO:0048471	perinuclear region of cytoplasm
0.55	GO:0043025	neuronal cell body
0.53	GO:0030425	dendrite
0.51	GO:0005654	nucleoplasm
0.51	GO:0005829	cytosol
0.46	GO:0005739	mitochondrion
0.43	GO:0005840	ribosome

tr|T1FNG7|T1FNG7_HELRO
Uncharacterized protein
Search

SESN3

0.92

Sestrin 3

0.85	GO:1901031	regulation of response to reactive oxygen species
0.62	GO:1904262	negative regulation of TORC1 signaling
0.60	GO:0034198	cellular response to amino acid starvation
0.60	GO:0042149	cellular response to glucose starvation
0.59	GO:0071230	cellular response to amino acid stimulus
0.58	GO:0032868	response to insulin
0.57	GO:0042593	glucose homeostasis
0.54	GO:1902010	negative regulation of translation in response to endoplasmic reticulum stress
0.53	GO:0038203	TORC2 signaling
0.52	GO:0046626	regulation of insulin receptor signaling pathway

0.53	GO:0070728	leucine binding
0.51	GO:0032542	sulfiredoxin activity
0.49	GO:0005092	GDP-dissociation inhibitor activity
0.45	GO:0016684	oxidoreductase activity, acting on peroxide as acceptor
0.35	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.61	GO:0061700	GATOR2 complex
0.58	GO:0031932	TORC2 complex
0.50	GO:1990316	Atg1/ULK1 kinase complex
0.50	GO:0031588	nucleotide-activated protein kinase complex
0.41	GO:0005739	mitochondrion
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.51

EC:1.8.98.2

GO:0032542

tr|T1FNG8|T1FNG8_HELRO
Uncharacterized protein
Search

0.48	GTP-binding protein ypt1

0.53	GO:1990261	pre-mRNA catabolic process
0.52	GO:0048211	Golgi vesicle docking
0.52	GO:0035493	SNARE complex assembly
0.51	GO:0035494	SNARE complex disassembly
0.51	GO:0034498	early endosome to Golgi transport
0.51	GO:0061709	reticulophagy
0.51	GO:1900101	regulation of endoplasmic reticulum unfolded protein response
0.51	GO:0034497	protein localization to phagophore assembly site
0.50	GO:0006888	ER to Golgi vesicle-mediated transport
0.50	GO:0032258	protein localization by the Cvt pathway

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.49	GO:0000149	SNARE binding
0.32	GO:0046872	metal ion binding

0.51	GO:0005794	Golgi apparatus
0.50	GO:0000407	phagophore assembly site
0.49	GO:0005801	cis-Golgi network
0.48	GO:0005789	endoplasmic reticulum membrane
0.47	GO:0098588	bounding membrane of organelle
0.46	GO:1904115	axon cytoplasm
0.46	GO:0097610	cell surface furrow
0.45	GO:0031982	vesicle
0.44	GO:0032155	cell division site part
0.44	GO:0005829	cytosol

tr|T1FNG9|T1FNG9_HELRO
Ferritin
Search

0.54	Soma ferritin

0.76	GO:0006879	cellular iron ion homeostasis
0.75	GO:0006826	iron ion transport
0.47	GO:0055114	oxidation-reduction process
0.43	GO:0051238	sequestering of metal ion
0.41	GO:0051651	maintenance of location in cell
0.38	GO:0008285	negative regulation of cell proliferation
0.36	GO:0006955	immune response
0.36	GO:0048145	regulation of fibroblast proliferation
0.34	GO:0060547	negative regulation of necrotic cell death
0.34	GO:0050829	defense response to Gram-negative bacterium

0.75	GO:0008199	ferric iron binding
0.68	GO:0016724	oxidoreductase activity, oxidizing metal ions, oxygen as acceptor
0.33	GO:0005515	protein binding

0.38	GO:0044754	autolysosome
0.35	GO:0005739	mitochondrion
0.35	GO:0071682	endocytic vesicle lumen
0.34	GO:0070288	ferritin complex
0.34	GO:0005576	extracellular region
0.32	GO:0005634	nucleus

0.68

EC:1.16.3

GO:0016724

tr|T1FNH0|T1FNH0_HELRO
Uncharacterized protein
Search

0.10	Thiopurine S-methyltransferase (Fragment)

0.76	GO:0010038	response to metal ion
0.63	GO:0032259	methylation

0.84

GO:0008119

thiopurine S-methyltransferase activity

0.48

GO:0005737

cytoplasm

0.84

EC:2.1.1.67

GO:0008119

tr|T1FNH1|T1FNH1_HELRO
Uncharacterized protein
Search

0.50	GO:0019706	protein-cysteine S-palmitoyltransferase activity
0.49	GO:0016779	nucleotidyltransferase activity
0.43	GO:0005515	protein binding

0.30

GO:0044425

membrane part

0.50

EC:2.3.1.225

GO:0019706

tr|T1FNH2|T1FNH2_HELRO
Uncharacterized protein
Search

CHMP1A

0.96	Charged multivesicular body protein 1a

0.78	GO:0007034	vacuolar transport
0.73	GO:0007076	mitotic chromosome condensation
0.61	GO:0016192	vesicle-mediated transport
0.52	GO:0045014	negative regulation of transcription by glucose
0.52	GO:1901673	regulation of mitotic spindle assembly
0.52	GO:0000920	cell separation after cytokinesis
0.51	GO:0007080	mitotic metaphase plate congression
0.51	GO:0010824	regulation of centrosome duplication
0.50	GO:0006997	nucleus organization
0.48	GO:0016458	gene silencing

0.48	GO:0019904	protein domain specific binding
0.47	GO:0042803	protein homodimerization activity
0.33	GO:0008237	metallopeptidase activity
0.33	GO:0008270	zinc ion binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.77	GO:0000815	ESCRT III complex
0.75	GO:0016363	nuclear matrix
0.49	GO:0005769	early endosome
0.49	GO:0000794	condensed nuclear chromosome
0.47	GO:0005815	microtubule organizing center
0.36	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

tr|T1FNH3|T1FNH3_HELRO
Uncharacterized protein
Search

0.76

Calpain B

0.61	GO:0006508	proteolysis
0.47	GO:0045214	sarcomere organization
0.39	GO:0010940	positive regulation of necrotic cell death
0.37	GO:0051493	regulation of cytoskeleton organization
0.36	GO:0030163	protein catabolic process
0.34	GO:0001578	microtubule bundle formation

0.82	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.65	GO:0005509	calcium ion binding
0.34	GO:0008017	microtubule binding

0.45	GO:0005622	intracellular
0.37	GO:0099512	supramolecular fiber
0.35	GO:0043228	non-membrane-bounded organelle
0.34	GO:0044422	organelle part
0.30	GO:0031224	intrinsic component of membrane

tr|T1FNH4|T1FNH4_HELRO
Uncharacterized protein
Search

NCS-2

0.52	Calcium-binding protein M

0.36	GO:1903169	regulation of calcium ion transmembrane transport
0.36	GO:0090281	negative regulation of calcium ion import
0.36	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.36	GO:0010523	negative regulation of calcium ion transport into cytosol
0.36	GO:1904063	negative regulation of cation transmembrane transport
0.35	GO:0042327	positive regulation of phosphorylation
0.34	GO:0071277	cellular response to calcium ion
0.34	GO:2001257	regulation of cation channel activity
0.34	GO:0048839	inner ear development
0.33	GO:0043085	positive regulation of catalytic activity

0.70	GO:0005509	calcium ion binding
0.36	GO:0098744	1-phosphatidylinositol 4-kinase activator activity
0.34	GO:0008061	chitin binding
0.33	GO:0004252	serine-type endopeptidase activity
0.33	GO:0042802	identical protein binding
0.33	GO:0003779	actin binding

0.33	GO:0000139	Golgi membrane
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0004252

tr|T1FNH5|T1FNH5_HELRO
Uncharacterized protein
Search

0.70	GO:0006955	immune response
0.64	GO:0006898	receptor-mediated endocytosis
0.54	GO:0072376	protein activation cascade
0.52	GO:0002253	activation of immune response
0.51	GO:0002252	immune effector process
0.40	GO:0038007	netrin-activated signaling pathway
0.38	GO:0000272	polysaccharide catabolic process
0.36	GO:0006508	proteolysis

0.71	GO:0005044	scavenger receptor activity
0.69	GO:0001871	pattern binding
0.62	GO:0030246	carbohydrate binding
0.42	GO:0005509	calcium ion binding
0.40	GO:0005042	netrin receptor activity
0.37	GO:0008237	metallopeptidase activity

0.55	GO:0005579	membrane attack complex
0.40	GO:0005576	extracellular region

tr|T1FNH6|T1FNH6_HELRO
Uncharacterized protein
Search

CDK1

0.68	Cyclin-dependent kinase

0.63	GO:0006468	protein phosphorylation
0.52	GO:1905448	positive regulation of mitochondrial ATP synthesis coupled electron transport
0.51	GO:0051726	regulation of cell cycle
0.51	GO:0044772	mitotic cell cycle phase transition
0.49	GO:0034501	protein localization to kinetochore
0.49	GO:0018210	peptidyl-threonine modification
0.48	GO:1900182	positive regulation of protein localization to nucleus
0.48	GO:0016570	histone modification
0.48	GO:0018209	peptidyl-serine modification
0.47	GO:0030154	cell differentiation

0.69	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0097472	cyclin-dependent protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.50	GO:0035173	histone kinase activity
0.49	GO:0030544	Hsp70 protein binding
0.48	GO:0030332	cyclin binding
0.46	GO:0003682	chromatin binding

0.52	GO:0097125	cyclin B1-CDK1 complex
0.51	GO:0072686	mitotic spindle
0.48	GO:0030496	midbody
0.48	GO:0005876	spindle microtubule
0.48	GO:0005815	microtubule organizing center
0.46	GO:0005759	mitochondrial matrix
0.44	GO:0005634	nucleus
0.44	GO:0005829	cytosol
0.35	GO:0070062	extracellular exosome
0.35	GO:0000781	chromosome, telomeric region

0.69

GO:0004674

tr|T1FNH7|T1FNH7_HELRO
Uncharacterized protein
Search

0.42	Fibrinolytic protease

0.61	GO:0006508	proteolysis
0.38	GO:0008544	epidermis development
0.38	GO:0016310	phosphorylation
0.37	GO:0007596	blood coagulation
0.33	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan
0.33	GO:0006956	complement activation
0.33	GO:0007586	digestion
0.33	GO:0008219	cell death
0.32	GO:0009166	nucleotide catabolic process
0.32	GO:0005975	carbohydrate metabolic process

0.69	GO:0004252	serine-type endopeptidase activity
0.38	GO:0016301	kinase activity
0.37	GO:0005509	calcium ion binding
0.33	GO:0008201	heparin binding
0.33	GO:0030246	carbohydrate binding
0.33	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.32	GO:0003924	GTPase activity
0.32	GO:0016788	hydrolase activity, acting on ester bonds
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0019001	guanyl nucleotide binding

0.37	GO:0005576	extracellular region
0.33	GO:0001669	acrosomal vesicle
0.32	GO:0005887	integral component of plasma membrane

0.69

GO:0004252

tr|T1FNH8|T1FNH8_HELRO
Uncharacterized protein
Search

0.46	Plasminogen activator sPA

0.61	GO:0006508	proteolysis
0.40	GO:0016310	phosphorylation
0.38	GO:0007596	blood coagulation
0.37	GO:0006898	receptor-mediated endocytosis
0.35	GO:0046598	positive regulation of viral entry into host cell
0.34	GO:1900047	negative regulation of hemostasis
0.34	GO:0050819	negative regulation of coagulation
0.34	GO:0061045	negative regulation of wound healing
0.34	GO:0030193	regulation of blood coagulation
0.34	GO:0007586	digestion

0.69	GO:0004252	serine-type endopeptidase activity
0.41	GO:0016301	kinase activity
0.38	GO:0005044	scavenger receptor activity
0.37	GO:0005509	calcium ion binding

0.38	GO:0005576	extracellular region
0.33	GO:0005737	cytoplasm
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.69

GO:0004252

tr|T1FNH9|T1FNH9_HELRO
Uncharacterized protein
Search

0.65	LOW QUALITY PROTEIN: gamma-aminobutyric acid receptor subunit rho-3

0.61	GO:0007165	signal transduction
0.60	GO:0034220	ion transmembrane transport
0.34	GO:0006821	chloride transport
0.33	GO:0006508	proteolysis
0.33	GO:0006355	regulation of transcription, DNA-templated

0.75	GO:0005230	extracellular ligand-gated ion channel activity
0.70	GO:0004888	transmembrane signaling receptor activity
0.33	GO:0070001	aspartic-type peptidase activity
0.33	GO:0140110	transcription regulator activity
0.33	GO:0004175	endopeptidase activity

0.54	GO:0005886	plasma membrane
0.35	GO:1902711	GABA-A receptor complex
0.32	GO:0016592	mediator complex
0.30	GO:0016021	integral component of membrane

tr|T1FNI0|T1FNI0_HELRO
Uncharacterized protein
Search

SLC25A3

0.88	Phosphate carrier proteinserine-threonine

0.43	GO:0006839	mitochondrial transport
0.43	GO:0035435	phosphate ion transmembrane transport
0.34	GO:1902600	hydrogen ion transmembrane transport

0.47	GO:0032403	protein complex binding
0.43	GO:0015114	phosphate ion transmembrane transporter activity
0.38	GO:0015317	phosphate:proton symporter activity

0.50	GO:0043209	myelin sheath
0.44	GO:0031966	mitochondrial membrane
0.44	GO:0019866	organelle inner membrane
0.36	GO:0070062	extracellular exosome
0.33	GO:0005887	integral component of plasma membrane

tr|T1FNI1|T1FNI1_HELRO
Uncharacterized protein
Search

UBE2A

0.49	Ubiquitin conjugating enzyme

0.48	GO:0016574	histone ubiquitination
0.47	GO:0000209	protein polyubiquitination
0.47	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.45	GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
0.45	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator
0.44	GO:0051865	protein autoubiquitination
0.44	GO:0051299	centrosome separation
0.44	GO:0006281	DNA repair
0.44	GO:0048522	positive regulation of cellular process
0.44	GO:0061726	mitochondrion disassembly

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0031625	ubiquitin protein ligase binding
0.46	GO:0061631	ubiquitin conjugating enzyme activity
0.44	GO:0002039	p53 binding
0.42	GO:0061630	ubiquitin protein ligase activity
0.41	GO:0019904	protein domain specific binding
0.39	GO:0016874	ligase activity

0.50	GO:0033503	HULC complex
0.44	GO:0001741	XY body
0.44	GO:0000790	nuclear chromatin
0.37	GO:0005737	cytoplasm
0.35	GO:0005657	replication fork
0.30	GO:0016020	membrane

0.39

GO:0016874

tr|T1FNI2|T1FNI2_HELRO
Uncharacterized protein
Search

SLC39A7

0.55	Zinc transporter

0.66	GO:0030001	metal ion transport
0.55	GO:0055085	transmembrane transport
0.42	GO:0006882	cellular zinc ion homeostasis
0.40	GO:2000274	regulation of epithelial cell migration, open tracheal system
0.40	GO:0010312	detoxification of zinc ion
0.39	GO:0042069	regulation of catecholamine metabolic process
0.39	GO:0072511	divalent inorganic cation transport
0.39	GO:0007298	border follicle cell migration
0.36	GO:0050790	regulation of catalytic activity
0.35	GO:0042147	retrograde transport, endosome to Golgi

0.69	GO:0046873	metal ion transmembrane transporter activity
0.40	GO:0072509	divalent inorganic cation transmembrane transporter activity
0.36	GO:0030234	enzyme regulator activity

0.39	GO:0097038	perinuclear endoplasmic reticulum
0.38	GO:0008021	synaptic vesicle
0.38	GO:0043025	neuronal cell body
0.38	GO:0030424	axon
0.35	GO:0030904	retromer complex
0.34	GO:0005829	cytosol
0.34	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0005794	Golgi apparatus
0.30	GO:0016021	integral component of membrane

tr|T1FNI3|T1FNI3_HELRO
Uncharacterized protein
Search

CCT6A

0.82	Chaperonin containing T-complex polypeptide subunit zeta

0.69	GO:0006457	protein folding
0.47	GO:1901998	toxin transport
0.47	GO:1904869	regulation of protein localization to Cajal body
0.47	GO:1904851	positive regulation of establishment of protein localization to telomere
0.46	GO:1904874	positive regulation of telomerase RNA localization to Cajal body
0.46	GO:0032212	positive regulation of telomere maintenance via telomerase
0.45	GO:1900182	positive regulation of protein localization to nucleus
0.44	GO:0050821	protein stabilization
0.36	GO:0007339	binding of sperm to zona pellucida
0.34	GO:0051131	chaperone-mediated protein complex assembly

0.71	GO:0051082	unfolded protein binding
0.55	GO:0044183	protein binding involved in protein folding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0071987	WD40-repeat domain binding
0.33	GO:0003723	RNA binding
0.33	GO:0008565	protein transporter activity

0.58	GO:0005832	chaperonin-containing T-complex
0.42	GO:0005874	microtubule
0.37	GO:0002199	zona pellucida receptor complex
0.36	GO:0001669	acrosomal vesicle
0.36	GO:0031012	extracellular matrix
0.36	GO:0070062	extracellular exosome
0.36	GO:0044297	cell body
0.30	GO:0016020	membrane

tr|T1FNI4|T1FNI4_HELRO
Uncharacterized protein
Search

0.63	Protein PLANT CADMIUM RESISTANCE 2

tr|T1FNI5|T1FNI5_HELRO
Uncharacterized protein
Search

STX5

0.76	Syntaxin-5

0.69	GO:0016192	vesicle-mediated transport
0.68	GO:0006886	intracellular protein transport
0.67	GO:0061025	membrane fusion
0.53	GO:0007030	Golgi organization
0.51	GO:1903358	regulation of Golgi organization
0.49	GO:0048308	organelle inheritance
0.49	GO:1903008	organelle disassembly
0.48	GO:0060305	regulation of cell diameter
0.47	GO:0016482	cytosolic transport
0.47	GO:0045732	positive regulation of protein catabolic process

0.79	GO:0005484	SNAP receptor activity
0.49	GO:0047485	protein N-terminus binding
0.48	GO:0045296	cadherin binding
0.46	GO:0000149	SNARE binding
0.42	GO:0042803	protein homodimerization activity
0.35	GO:0031625	ubiquitin protein ligase binding

0.50	GO:0005794	Golgi apparatus
0.46	GO:0031201	SNARE complex
0.45	GO:0031982	vesicle
0.44	GO:0005801	cis-Golgi network
0.43	GO:0005829	cytosol
0.42	GO:0098588	bounding membrane of organelle
0.42	GO:0031984	organelle subcompartment
0.38	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.36	GO:0005783	endoplasmic reticulum
0.34	GO:0098793	presynapse

tr|T1FNI6|T1FNI6_HELRO
Uncharacterized protein
Search

SEC23

0.58	Putative vesicle coat complex copii subunit sec23

0.82	GO:0090114	COPII-coated vesicle budding
0.69	GO:0006886	intracellular protein transport
0.48	GO:0048081	positive regulation of cuticle pigmentation
0.48	GO:0003331	positive regulation of extracellular matrix constituent secretion
0.47	GO:0035293	chitin-based larval cuticle pattern formation
0.47	GO:0035149	lumen formation, open tracheal system
0.46	GO:0016203	muscle attachment
0.46	GO:0050775	positive regulation of dendrite morphogenesis
0.46	GO:0034394	protein localization to cell surface
0.46	GO:0071711	basement membrane organization

0.62	GO:0008270	zinc ion binding
0.39	GO:0005096	GTPase activator activity
0.33	GO:0005515	protein binding

0.80	GO:0030127	COPII vesicle coat
0.74	GO:0000139	Golgi membrane
0.48	GO:0070971	endoplasmic reticulum exit site
0.44	GO:0005795	Golgi stack
0.37	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0019898	extrinsic component of membrane
0.36	GO:0005829	cytosol
0.34	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

tr|T1FNI7|T1FNI7_HELRO
Uncharacterized protein
Search

GTF2B

0.58	Transcription initiation factor TFIIB

0.78	GO:0070897	DNA-templated transcriptional preinitiation complex assembly
0.62	GO:0006413	translational initiation
0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.52	GO:1904798	positive regulation of core promoter binding
0.48	GO:0050434	positive regulation of viral transcription
0.48	GO:0006367	transcription initiation from RNA polymerase II promoter
0.35	GO:0042795	snRNA transcription by RNA polymerase II
0.34	GO:0097052	L-kynurenine metabolic process

0.79	GO:0017025	TBP-class protein binding
0.63	GO:0003743	translation initiation factor activity
0.52	GO:0046872	metal ion binding
0.51	GO:0046966	thyroid hormone receptor binding
0.50	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding
0.35	GO:0036137	kynurenine aminotransferase activity
0.33	GO:0030170	pyridoxal phosphate binding

0.51	GO:0097550	transcriptional preinitiation complex
0.48	GO:0005669	transcription factor TFIID complex
0.47	GO:0016604	nuclear body
0.30	GO:0016020	membrane

tr|T1FNI8|T1FNI8_HELRO
Uncharacterized protein
Search

0.65	Transcriptional repressor scratch 1

0.51	GO:0048699	generation of neurons
0.49	GO:0006357	regulation of transcription by RNA polymerase II
0.48	GO:0030334	regulation of cell migration
0.47	GO:0051960	regulation of nervous system development
0.47	GO:0060284	regulation of cell development
0.46	GO:0036445	neuronal stem cell division
0.46	GO:0098722	asymmetric stem cell division
0.46	GO:0072089	stem cell proliferation
0.46	GO:0045892	negative regulation of transcription, DNA-templated
0.45	GO:0061351	neural precursor cell proliferation

0.51	GO:0003676	nucleic acid binding
0.44	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.34	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.34	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.42	GO:0016604	nuclear body
0.33	GO:0000790	nuclear chromatin
0.30	GO:0016020	membrane

tr|T1FNI9|T1FNI9_HELRO
Uncharacterized protein
Search

0.11	Mediator of RNA polymerase II transcription subunit 15

0.70	GO:0006357	regulation of transcription by RNA polymerase II
0.57	GO:0006351	transcription, DNA-templated
0.35	GO:0043547	positive regulation of GTPase activity

0.78	GO:0001104	RNA polymerase II transcription cofactor activity
0.36	GO:0005096	GTPase activator activity
0.34	GO:0003723	RNA binding
0.33	GO:0046872	metal ion binding

0.77

GO:0016592

mediator complex

tr|T1FNJ0|T1FNJ0_HELRO
Uncharacterized protein
Search

0.85	Pre-B-cell leukemia transcription factor

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.44	GO:0007438	oenocyte development
0.43	GO:0000060	protein import into nucleus, translocation
0.43	GO:0007525	somatic muscle development
0.43	GO:0042659	regulation of cell fate specification
0.43	GO:0007422	peripheral nervous system development
0.42	GO:0001654	eye development
0.41	GO:0007420	brain development

0.61	GO:0003700	DNA binding transcription factor activity
0.60	GO:0043565	sequence-specific DNA binding
0.42	GO:0033613	activating transcription factor binding
0.42	GO:0035326	enhancer binding
0.41	GO:0003713	transcription coactivator activity
0.40	GO:0046982	protein heterodimerization activity
0.34	GO:0004801	sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity

0.61	GO:0005634	nucleus
0.41	GO:0005667	transcription factor complex
0.39	GO:0032993	protein-DNA complex
0.35	GO:0005737	cytoplasm
0.34	GO:0000444	MIS12/MIND type complex
0.33	GO:0097708	intracellular vesicle
0.33	GO:0098805	whole membrane
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0012505	endomembrane system
0.33	GO:0098796	membrane protein complex

0.34

EC:2.2.1.2

GO:0004801

tr|T1FNJ1|T1FNJ1_HELRO
Uncharacterized protein
Search

0.73	Actin-related protein 2/3 complex subunit

0.81	GO:0034314	Arp2/3 complex-mediated actin nucleation
0.44	GO:0030589	pseudocleavage involved in syncytial blastoderm formation
0.43	GO:0030037	actin filament reorganization involved in cell cycle
0.43	GO:0008407	chaeta morphogenesis
0.43	GO:0033627	cell adhesion mediated by integrin
0.42	GO:0007413	axonal fasciculation
0.42	GO:0051491	positive regulation of filopodium assembly
0.42	GO:0045747	positive regulation of Notch signaling pathway
0.42	GO:0001745	compound eye morphogenesis
0.41	GO:0007409	axonogenesis

0.68	GO:0003779	actin binding
0.39	GO:0032403	protein complex binding
0.38	GO:0043130	ubiquitin binding
0.33	GO:0005200	structural constituent of cytoskeleton

0.80	GO:0005885	Arp2/3 protein complex
0.47	GO:0030479	actin cortical patch
0.30	GO:0031224	intrinsic component of membrane

tr|T1FNJ2|T1FNJ2_HELRO
DNA-(apurinic or apyrimidinic site) lyase
Search

APEX1

0.64	DNA-(apurinic or apyrimidinic site) lyase

0.65	GO:0006281	DNA repair
0.64	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.48	GO:0043247	telomere maintenance in response to DNA damage
0.48	GO:0080111	DNA demethylation
0.47	GO:0043488	regulation of mRNA stability
0.45	GO:0042981	regulation of apoptotic process
0.42	GO:0045454	cell redox homeostasis
0.39	GO:1903506	regulation of nucleic acid-templated transcription
0.39	GO:0014912	negative regulation of smooth muscle cell migration
0.38	GO:0071320	cellular response to cAMP

0.70	GO:0140080	class III/IV DNA-(apurinic or apyrimidinic site) lyase activity
0.70	GO:0140078	class I DNA-(apurinic or apyrimidinic site) lyase activity
0.66	GO:0004519	endonuclease activity
0.55	GO:0003677	DNA binding
0.51	GO:0008309	double-stranded DNA exodeoxyribonuclease activity
0.50	GO:0046872	metal ion binding
0.46	GO:0008408	3'-5' exonuclease activity
0.45	GO:0003713	transcription coactivator activity
0.45	GO:0003682	chromatin binding
0.43	GO:0008081	phosphoric diester hydrolase activity

0.50	GO:0005634	nucleus
0.49	GO:0005739	mitochondrion
0.45	GO:0048471	perinuclear region of cytoplasm
0.45	GO:0005813	centrosome
0.42	GO:0031974	membrane-enclosed lumen
0.38	GO:0005783	endoplasmic reticulum
0.37	GO:0005667	transcription factor complex
0.33	GO:0000781	chromosome, telomeric region
0.32	GO:0005840	ribosome

0.43

EC:3.1.4

GO:0008081

tr|T1FNJ3|T1FNJ3_HELRO
Histone H2B
Search

0.43	GO:0006334	nucleosome assembly
0.34	GO:0006352	DNA-templated transcription, initiation

0.74	GO:0046982	protein heterodimerization activity
0.55	GO:0003677	DNA binding

0.75	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.43	GO:0031248	protein acetyltransferase complex
0.41	GO:0031974	membrane-enclosed lumen
0.39	GO:0043234	protein complex

tr|T1FNJ4|T1FNJ4_HELRO
Uncharacterized protein
Search

0.39	Apoptosis-promoting RNA-binding protein TIA-1/TIAR

0.48	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.37	GO:0000398	mRNA splicing, via spliceosome
0.32	GO:0006508	proteolysis

0.59	GO:0003723	RNA binding
0.33	GO:0005509	calcium ion binding
0.33	GO:0070001	aspartic-type peptidase activity
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.33	GO:0004175	endopeptidase activity
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003677	DNA binding

0.38	GO:0005685	U1 snRNP
0.34	GO:0019013	viral nucleocapsid
0.30	GO:0016020	membrane

tr|T1FNJ5|T1FNJ5_HELRO
Ubiquinone biosynthesis O-methyltransferase, mitochondrial
Search

UBIG

0.48	Ubiquinone biosynthesis O-methyltransferase

0.75	GO:0006744	ubiquinone biosynthetic process
0.63	GO:0032259	methylation
0.38	GO:0002119	nematode larval development
0.35	GO:0000188	inactivation of MAPK activity
0.34	GO:0006470	protein dephosphorylation
0.33	GO:0007264	small GTPase mediated signal transduction
0.33	GO:0043547	positive regulation of GTPase activity
0.33	GO:0015031	protein transport

0.80	GO:0008425	2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity
0.79	GO:0061542	3-demethylubiquinone-n 3-O-methyltransferase activity
0.64	GO:0010420	polyprenyldihydroxybenzoate methyltransferase activity
0.35	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity
0.34	GO:0005093	Rab GDP-dissociation inhibitor activity
0.33	GO:0005096	GTPase activator activity
0.33	GO:0052730	sarcosine N-methyltransferase activity
0.33	GO:0017174	glycine N-methyltransferase activity

0.60

GO:0031314

extrinsic component of mitochondrial inner membrane

0.80	EC:2.1.1	GO:0008425
0.33	KEGG:R07243	GO:0052730

tr|T1FNJ6|T1FNJ6_HELRO
Fe-S cluster assembly protein DRE2
Search

L(2)35BG

0.51	Fe-S cluster assembly protein DRE2

0.74	GO:0006915	apoptotic process
0.74	GO:0016226	iron-sulfur cluster assembly
0.73	GO:0043066	negative regulation of apoptotic process
0.63	GO:0030097	hemopoiesis
0.57	GO:0022900	electron transport chain
0.50	GO:0032259	methylation
0.43	GO:0030707	ovarian follicle cell development
0.39	GO:0036474	cell death in response to hydrogen peroxide
0.39	GO:0097468	programmed cell death in response to reactive oxygen species

0.71	GO:0051537	2 iron, 2 sulfur cluster binding
0.58	GO:0009055	electron transfer activity
0.54	GO:0046872	metal ion binding
0.51	GO:0008168	methyltransferase activity
0.33	GO:0005515	protein binding
0.32	GO:0003677	DNA binding

0.79	GO:0005758	mitochondrial intermembrane space
0.51	GO:0005634	nucleus
0.41	GO:0043232	intracellular non-membrane-bounded organelle

0.51

GO:0008168

tr|T1FNJ7|T1FNJ7_HELRO
Uncharacterized protein
Search

0.43

GO:0005515

protein binding

0.30

GO:0044425

membrane part

tr|T1FNJ8|T1FNJ8_HELRO
Uncharacterized protein
Search

SLC25A32

0.91	Mitochondrial folate transporter/carrier

0.53	GO:0006839	mitochondrial transport
0.47	GO:0035350	FAD transmembrane transport
0.47	GO:0015884	folic acid transport
0.44	GO:0006544	glycine metabolic process
0.36	GO:0035461	vitamin transmembrane transport
0.35	GO:0006855	drug transmembrane transport
0.35	GO:1903825	organic acid transmembrane transport
0.34	GO:0046655	folic acid metabolic process
0.34	GO:0015883	FAD transport

0.47	GO:0015230	FAD transmembrane transporter activity
0.47	GO:0008517	folic acid transmembrane transporter activity
0.32	GO:0016829	lyase activity
0.32	GO:0003677	DNA binding
0.31	GO:0016740	transferase activity

0.46	GO:0005739	mitochondrion
0.46	GO:0031967	organelle envelope
0.45	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.32

EC:4

GO:0016829

tr|T1FNJ9|T1FNJ9_HELRO
Uncharacterized protein
Search

CTSB

0.81	Procathepsin B

0.68	GO:0050790	regulation of catalytic activity
0.61	GO:0006508	proteolysis
0.53	GO:0097067	cellular response to thyroid hormone stimulus
0.52	GO:0030574	collagen catabolic process
0.50	GO:0046697	decidualization
0.49	GO:0060429	epithelium development
0.47	GO:0044257	cellular protein catabolic process
0.46	GO:0030154	cell differentiation
0.44	GO:0051806	entry into cell of other organism involved in symbiotic interaction
0.44	GO:0044409	entry into host

0.75	GO:0004197	cysteine-type endopeptidase activity
0.51	GO:0043394	proteoglycan binding
0.50	GO:0005518	collagen binding
0.35	GO:0030984	kininogen binding
0.34	GO:0043621	protein self-association
0.34	GO:0042277	peptide binding
0.33	GO:0004252	serine-type endopeptidase activity

0.51	GO:0005764	lysosome
0.48	GO:0048471	perinuclear region of cytoplasm
0.48	GO:0005615	extracellular space
0.46	GO:0005730	nucleolus
0.41	GO:0005739	mitochondrion
0.41	GO:0042470	melanosome
0.35	GO:1903561	extracellular vesicle
0.35	GO:0031904	endosome lumen
0.35	GO:1904813	ficolin-1-rich granule lumen
0.34	GO:0005775	vacuolar lumen

0.75

EC:3.4.22

GO:0004197

tr|T1FNK0|T1FNK0_HELRO
Uncharacterized protein
Search

ARL4C

0.93	ADP ribosylation factor like GTPase 4A

0.50	GO:0032456	endocytic recycling
0.34	GO:0016579	protein deubiquitination
0.33	GO:0006511	ubiquitin-dependent protein catabolic process

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0043014	alpha-tubulin binding
0.34	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.33	GO:0003924	GTPase activity
0.32	GO:0003676	nucleic acid binding

0.45	GO:0005622	intracellular
0.44	GO:0032154	cleavage furrow
0.40	GO:0005886	plasma membrane
0.36	GO:0030175	filopodium
0.32	GO:0043227	membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.34

GO:0036459

tr|T1FNK1|T1FNK1_HELRO
Uncharacterized protein
Search

AK1

0.42	Adenylate kinase isoenzyme 1

0.63	GO:0006172	ADP biosynthetic process
0.59	GO:0046939	nucleotide phosphorylation
0.57	GO:0046033	AMP metabolic process
0.54	GO:0009142	nucleoside triphosphate biosynthetic process
0.53	GO:0046034	ATP metabolic process
0.42	GO:0007050	cell cycle arrest
0.38	GO:0009112	nucleobase metabolic process
0.38	GO:0006221	pyrimidine nucleotide biosynthetic process
0.37	GO:0097503	sialylation
0.36	GO:0006486	protein glycosylation

0.72	GO:0019205	nucleobase-containing compound kinase activity
0.61	GO:0016776	phosphotransferase activity, phosphate group as acceptor
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0008373	sialyltransferase activity

0.44	GO:0005737	cytoplasm
0.42	GO:0036126	sperm flagellum
0.39	GO:0044441	ciliary part
0.38	GO:0099513	polymeric cytoskeletal fiber
0.36	GO:0005886	plasma membrane
0.34	GO:0005634	nucleus
0.34	GO:0070062	extracellular exosome
0.34	GO:0043005	neuron projection
0.30	GO:0016021	integral component of membrane

0.61

EC:2.7.4

GO:0016776

tr|T1FNK2|T1FNK2_HELRO
Uncharacterized protein
Search

SRSF1

0.89	Serine and arginine rich splicing factor 1

0.48	GO:0048025	negative regulation of mRNA splicing, via spliceosome
0.46	GO:0000395	mRNA 5'-splice site recognition
0.46	GO:0000380	alternative mRNA splicing, via spliceosome
0.45	GO:0060048	cardiac muscle contraction
0.44	GO:0001701	in utero embryonic development
0.37	GO:0043279	response to alkaloid
0.35	GO:0051028	mRNA transport
0.35	GO:0097421	liver regeneration
0.35	GO:0009636	response to toxic substance
0.35	GO:0033120	positive regulation of RNA splicing

0.59	GO:0003723	RNA binding
0.49	GO:0019904	protein domain specific binding
0.47	GO:0044547	DNA topoisomerase binding
0.35	GO:0043422	protein kinase B binding

0.47	GO:0005654	nucleoplasm
0.46	GO:0035145	exon-exon junction complex
0.44	GO:0071013	catalytic step 2 spliceosome
0.43	GO:0005730	nucleolus
0.34	GO:0070062	extracellular exosome
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|T1FNK3|T1FNK3_HELRO
Glutamine synthetase
Search

0.46	Glutamine synthetase

0.76	GO:0006542	glutamine biosynthetic process
0.36	GO:0008283	cell proliferation
0.36	GO:0009749	response to glucose
0.35	GO:0009267	cellular response to starvation
0.33	GO:0006468	protein phosphorylation

0.76	GO:0004356	glutamate-ammonia ligase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0004351	glutamate decarboxylase activity
0.36	GO:0042802	identical protein binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0003723	RNA binding

0.37	GO:0097386	glial cell projection
0.36	GO:0043209	myelin sheath
0.36	GO:0005739	mitochondrion
0.35	GO:0044297	cell body
0.35	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.76	EC:6.3.1.2	GO:0004356
0.76	KEGG:R00253	GO:0004356

tr|T1FNK4|T1FNK4_HELRO
Uncharacterized protein
Search

CCT8

0.78	T-complex protein 1 subunit theta

0.69	GO:0006457	protein folding
0.51	GO:1904869	regulation of protein localization to Cajal body
0.51	GO:1904851	positive regulation of establishment of protein localization to telomere
0.51	GO:1904874	positive regulation of telomerase RNA localization to Cajal body
0.50	GO:0032212	positive regulation of telomere maintenance via telomerase
0.49	GO:0046931	pore complex assembly
0.49	GO:0007339	binding of sperm to zona pellucida
0.48	GO:1900182	positive regulation of protein localization to nucleus
0.47	GO:0050821	protein stabilization
0.47	GO:1901998	toxin transport

0.71	GO:0051082	unfolded protein binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0045296	cadherin binding
0.48	GO:0044183	protein binding involved in protein folding
0.33	GO:0070001	aspartic-type peptidase activity
0.33	GO:0004175	endopeptidase activity
0.33	GO:0042623	ATPase activity, coupled

0.54	GO:0005832	chaperonin-containing T-complex
0.50	GO:0002199	zona pellucida receptor complex
0.47	GO:0044297	cell body
0.47	GO:0005815	microtubule organizing center
0.47	GO:0045111	intermediate filament cytoskeleton
0.45	GO:0005874	microtubule
0.44	GO:0005654	nucleoplasm
0.38	GO:0005929	cilium
0.36	GO:0070062	extracellular exosome
0.35	GO:1904813	ficolin-1-rich granule lumen

tr|T1FNK5|T1FNK5_HELRO
Uncharacterized protein
Search

ACADVL

0.34	Very long-chain specific acyl-mitochondrial

0.53	GO:0055114	oxidation-reduction process
0.50	GO:0046322	negative regulation of fatty acid oxidation
0.49	GO:0090181	regulation of cholesterol metabolic process
0.49	GO:0001659	temperature homeostasis
0.48	GO:0045717	negative regulation of fatty acid biosynthetic process
0.47	GO:0009409	response to cold
0.46	GO:0030855	epithelial cell differentiation
0.45	GO:0009062	fatty acid catabolic process
0.44	GO:0030258	lipid modification
0.35	GO:0060322	head development

0.74	GO:0003995	acyl-CoA dehydrogenase activity
0.66	GO:0050660	flavin adenine dinucleotide binding
0.34	GO:0000062	fatty-acyl-CoA binding
0.34	GO:0047429	nucleoside-triphosphate diphosphatase activity
0.33	GO:0008289	lipid binding
0.32	GO:0003677	DNA binding

0.47	GO:0042645	mitochondrial nucleoid
0.44	GO:0005730	nucleolus
0.42	GO:0005829	cytosol
0.41	GO:0031966	mitochondrial membrane
0.35	GO:0019866	organelle inner membrane
0.35	GO:0036128	CatSper complex

0.74

EC:1.3.99.3

GO:0003995

tr|T1FNK6|T1FNK6_HELRO
Uncharacterized protein
Search

LOC106155641

0.75	Sodium/potassium/calcium exchanger 6, mitochondrial

0.55	GO:0055085	transmembrane transport
0.53	GO:0086036	regulation of cardiac muscle cell membrane potential
0.53	GO:1901660	calcium ion export
0.52	GO:1901623	regulation of lymphocyte chemotaxis
0.51	GO:0051560	mitochondrial calcium ion homeostasis
0.51	GO:2001256	regulation of store-operated calcium entry
0.50	GO:0051283	negative regulation of sequestering of calcium ion
0.50	GO:0050796	regulation of insulin secretion
0.50	GO:0060402	calcium ion transport into cytosol
0.49	GO:0042593	glucose homeostasis

0.54	GO:0086038	calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential
0.47	GO:0042803	protein homodimerization activity

0.52	GO:0030061	mitochondrial crista
0.48	GO:0032592	integral component of mitochondrial membrane
0.43	GO:0042383	sarcolemma

tr|T1FNK7|T1FNK7_HELRO
Uncharacterized protein
Search

MAB21L2

0.94	Mab-21 like 1

0.79	GO:0043010	camera-type eye development
0.74	GO:0008284	positive regulation of cell proliferation
0.66	GO:0010172	embryonic body morphogenesis
0.50	GO:0048048	embryonic eye morphogenesis
0.50	GO:0048701	embryonic cranial skeleton morphogenesis
0.36	GO:0007399	nervous system development
0.34	GO:0006351	transcription, DNA-templated
0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression

0.41	GO:0016779	nucleotidyltransferase activity
0.38	GO:0046872	metal ion binding
0.37	GO:1901265	nucleoside phosphate binding
0.37	GO:0036094	small molecule binding
0.36	GO:0005515	protein binding
0.33	GO:0097367	carbohydrate derivative binding
0.33	GO:0008144	drug binding
0.33	GO:0043168	anion binding

0.61	GO:0005634	nucleus
0.44	GO:0005737	cytoplasm

0.41

EC:2.7.7

GO:0016779

tr|T1FNK8|T1FNK8_HELRO
Uncharacterized protein
Search

tr|T1FNK9|T1FNK9_HELRO
Uncharacterized protein
Search

IFA-1

0.89	Intermediate filament gliarin

0.35	GO:0061564	axon development
0.33	GO:0060052	neurofilament cytoskeleton organization
0.33	GO:0006629	lipid metabolic process
0.32	GO:1990830	cellular response to leukemia inhibitory factor
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression
0.31	GO:0055114	oxidation-reduction process

0.62	GO:0005198	structural molecule activity
0.33	GO:0008081	phosphoric diester hydrolase activity
0.33	GO:0003677	DNA binding
0.33	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.32	GO:0046872	metal ion binding

0.79	GO:0005882	intermediate filament
0.36	GO:0016324	apical plasma membrane
0.34	GO:0005737	cytoplasm
0.33	GO:0005634	nucleus
0.32	GO:0043209	myelin sheath
0.32	GO:0035770	ribonucleoprotein granule
0.32	GO:0036338	viral membrane
0.32	GO:0012505	endomembrane system
0.32	GO:0031974	membrane-enclosed lumen
0.32	GO:0031967	organelle envelope

0.33

EC:3.1.4

GO:0008081

tr|T1FNL0|T1FNL0_HELRO
Uncharacterized protein
Search

GTPBP10

0.69	GTP-binding protein 10

0.42	GO:0042254	ribosome biogenesis
0.34	GO:0016310	phosphorylation

0.66	GO:0001883	purine nucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.65	GO:0032549	ribonucleoside binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0003924	GTPase activity
0.40	GO:0000287	magnesium ion binding
0.34	GO:0016301	kinase activity
0.33	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.41	GO:0005739	mitochondrion
0.37	GO:0005730	nucleolus
0.33	GO:0005694	chromosome

tr|T1FNL1|T1FNL1_HELRO
Uncharacterized protein
Search

GTDC1

0.77	Glycosyltransferase domain-containing protein 1

0.42	GO:0007417	central nervous system development
0.34	GO:0006506	GPI anchor biosynthetic process
0.34	GO:0051603	proteolysis involved in cellular protein catabolic process

0.49	GO:0016740	transferase activity
0.35	GO:0070003	threonine-type peptidase activity
0.34	GO:0004175	endopeptidase activity

0.35	GO:0005839	proteasome core complex
0.30	GO:0016020	membrane

0.49

GO:0016740

tr|T1FNL2|T1FNL2_HELRO
Uncharacterized protein
Search

0.50	GO:0006468	protein phosphorylation
0.45	GO:0007165	signal transduction
0.40	GO:0016567	protein ubiquitination
0.39	GO:0006952	defense response
0.37	GO:0006955	immune response

0.50	GO:0004672	protein kinase activity
0.45	GO:0030554	adenyl nucleotide binding
0.45	GO:0097367	carbohydrate derivative binding
0.44	GO:0008144	drug binding
0.44	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0004842	ubiquitin-protein transferase activity

0.30

GO:0031224

intrinsic component of membrane

0.41

GO:0004842

tr|T1FNL3|T1FNL3_HELRO
Serine/threonine-protein phosphatase
Search

PPP4C

0.50	Serine/threonine-protein phosphatase 4 catalytic subunit

0.71	GO:0006470	protein dephosphorylation
0.53	GO:0010569	regulation of double-strand break repair via homologous recombination
0.41	GO:0045879	negative regulation of smoothened signaling pathway
0.39	GO:0007346	regulation of mitotic cell cycle
0.39	GO:0000278	mitotic cell cycle
0.38	GO:0007017	microtubule-based process
0.38	GO:0048264	determination of ventral identity
0.36	GO:0038061	NIK/NF-kappaB signaling
0.36	GO:0030513	positive regulation of BMP signaling pathway
0.35	GO:0021952	central nervous system projection neuron axonogenesis

0.71	GO:0004721	phosphoprotein phosphatase activity
0.37	GO:0004704	NF-kappaB-inducing kinase activity
0.36	GO:0046872	metal ion binding
0.35	GO:0005515	protein binding
0.33	GO:0044877	macromolecular complex binding

0.54	GO:0030289	protein phosphatase 4 complex
0.45	GO:0005829	cytosol
0.45	GO:0005634	nucleus
0.44	GO:0005815	microtubule organizing center
0.40	GO:0005886	plasma membrane
0.39	GO:0000775	chromosome, centromeric region
0.33	GO:0031974	membrane-enclosed lumen

0.71

EC:3.1.3.16

GO:0004721

tr|T1FNL4|T1FNL4_HELRO
Uncharacterized protein
Search

RANBP1

0.88	RAN binding protein 1

0.69	GO:0046907	intracellular transport
0.54	GO:0046604	positive regulation of mitotic centrosome separation
0.50	GO:0007051	spindle organization
0.47	GO:0000082	G1/S transition of mitotic cell cycle
0.46	GO:0006606	protein import into nucleus
0.45	GO:0043547	positive regulation of GTPase activity
0.45	GO:0006405	RNA export from nucleus
0.44	GO:0006511	ubiquitin-dependent protein catabolic process
0.40	GO:0000413	protein peptidyl-prolyl isomerization
0.38	GO:0072750	cellular response to leptomycin B

0.46	GO:0008536	Ran GTPase binding
0.45	GO:0005096	GTPase activator activity
0.40	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.36	GO:0005092	GDP-dissociation inhibitor activity
0.36	GO:0045296	cadherin binding
0.36	GO:0016874	ligase activity
0.36	GO:0046872	metal ion binding

0.49	GO:0005813	centrosome
0.42	GO:0005829	cytosol
0.40	GO:0005634	nucleus
0.37	GO:1904115	axon cytoplasm
0.33	GO:0012505	endomembrane system
0.32	GO:0031967	organelle envelope
0.30	GO:0031224	intrinsic component of membrane

0.40

GO:0003755

tr|T1FNL5|T1FNL5_HELRO
Uncharacterized protein
Search

0.43	Zinc finger HIT domain-containing protein 1

0.43	GO:0031063	regulation of histone deacetylation
0.42	GO:0043486	histone exchange
0.34	GO:0006955	immune response
0.34	GO:0008380	RNA splicing
0.34	GO:0007084	mitotic nuclear envelope reassembly
0.34	GO:0032958	inositol phosphate biosynthetic process
0.34	GO:0006289	nucleotide-excision repair
0.34	GO:0035307	positive regulation of protein dephosphorylation
0.33	GO:0006099	tricarboxylic acid cycle
0.33	GO:2001141	regulation of RNA biosynthetic process

0.53	GO:0046872	metal ion binding
0.43	GO:0042826	histone deacetylase binding
0.42	GO:0031491	nucleosome binding
0.35	GO:0005164	tumor necrosis factor receptor binding
0.34	GO:0003994	aconitate hydratase activity
0.34	GO:0051721	protein phosphatase 2A binding
0.33	GO:0051539	4 iron, 4 sulfur cluster binding
0.32	GO:0016301	kinase activity

0.45	GO:0005700	polytene chromosome
0.42	GO:0000812	Swr1 complex
0.35	GO:0005737	cytoplasm
0.34	GO:0000439	core TFIIH complex
0.34	GO:0019013	viral nucleocapsid
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

0.34

EC:4.2.1.3

GO:0003994

tr|T1FNL6|T1FNL6_HELRO
Uncharacterized protein
Search

MPP6

0.92	Membrane palmitoylated protein 6

0.38

GO:0006461

protein complex assembly

0.49

GO:0030165

PDZ domain binding

0.55	GO:0005886	plasma membrane
0.44	GO:0070062	extracellular exosome
0.30	GO:0044425	membrane part

tr|T1FNL7|T1FNL7_HELRO
Uncharacterized protein
Search

tr|T1FNL8|T1FNL8_HELRO
Uncharacterized protein
Search

0.34	GO:0051716	cellular response to stimulus
0.34	GO:0023052	signaling
0.33	GO:0007154	cell communication
0.33	GO:0006468	protein phosphorylation
0.33	GO:0016999	antibiotic metabolic process
0.33	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.33	GO:0006950	response to stress
0.33	GO:0065007	biological regulation
0.33	GO:0006259	DNA metabolic process
0.32	GO:0055114	oxidation-reduction process

0.70	GO:0015020	glucuronosyltransferase activity
0.34	GO:0016788	hydrolase activity, acting on ester bonds
0.34	GO:0003697	single-stranded DNA binding
0.33	GO:0004672	protein kinase activity
0.33	GO:0031177	phosphopantetheine binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0016491	oxidoreductase activity

0.36	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016020	membrane

0.70

EC:2.4.1.17

GO:0015020

tr|T1FNL9|T1FNL9_HELRO
Uncharacterized protein
Search

RAB4B

0.77	Small GTP-binding protein Rab4

0.49	GO:0030100	regulation of endocytosis
0.43	GO:0007299	ovarian follicle cell-cell adhesion
0.38	GO:0015031	protein transport
0.38	GO:0046323	glucose import
0.37	GO:0032482	Rab protein signal transduction
0.36	GO:0002376	immune system process
0.35	GO:0001944	vasculature development
0.34	GO:0016192	vesicle-mediated transport
0.34	GO:0032781	positive regulation of ATPase activity
0.34	GO:0001775	cell activation

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0032561	guanyl ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0004767	sphingomyelin phosphodiesterase activity
0.35	GO:0008565	protein transporter activity
0.35	GO:0035255	ionotropic glutamate receptor binding
0.35	GO:0051117	ATPase binding
0.34	GO:0019905	syntaxin binding
0.34	GO:0001671	ATPase activator activity

0.49	GO:0005768	endosome
0.49	GO:0032593	insulin-responsive compartment
0.41	GO:0043025	neuronal cell body
0.40	GO:0045202	synapse
0.40	GO:0005739	mitochondrion
0.39	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0070062	extracellular exosome
0.36	GO:0044433	cytoplasmic vesicle part
0.36	GO:0098805	whole membrane
0.36	GO:0005886	plasma membrane

0.36	EC:3.1.4.12	GO:0004767
0.36	KEGG:R02541	GO:0004767

tr|T1FNM0|T1FNM0_HELRO
Uncharacterized protein
Search

NIT2

0.49	Carbon-nitrogen hydrolase

0.45	GO:0006807	nitrogen compound metabolic process
0.44	GO:0006107	oxaloacetate metabolic process
0.39	GO:0032787	monocarboxylic acid metabolic process
0.36	GO:0006108	malate metabolic process
0.33	GO:0010467	gene expression
0.33	GO:0008643	carbohydrate transport
0.32	GO:1901360	organic cyclic compound metabolic process
0.32	GO:0046483	heterocycle metabolic process
0.32	GO:0006725	cellular aromatic compound metabolic process
0.32	GO:0009059	macromolecule biosynthetic process

0.50	GO:0050152	omega-amidase activity
0.35	GO:0047417	N-carbamoyl-D-amino acid hydrolase activity
0.35	GO:0000213	tRNA-intron endonuclease activity
0.34	GO:0008270	zinc ion binding
0.34	GO:0016746	transferase activity, transferring acyl groups
0.34	GO:0003676	nucleic acid binding
0.33	GO:0004040	amidase activity

0.42	GO:0005813	centrosome
0.41	GO:0005829	cytosol
0.38	GO:0005739	mitochondrion
0.36	GO:0009570	chloroplast stroma
0.30	GO:0031224	intrinsic component of membrane

0.50

EC:3.5.1.3

GO:0050152

tr|T1FNM1|T1FNM1_HELRO
Uncharacterized protein
Search

XPNPEP3

0.63	X-prolyl aminopeptidase

0.61	GO:0006508	proteolysis
0.55	GO:0003094	glomerular filtration
0.47	GO:0051604	protein maturation
0.36	GO:0007369	gastrulation

0.73	GO:0030145	manganese ion binding
0.71	GO:0004177	aminopeptidase activity
0.36	GO:0102009	proline dipeptidase activity
0.34	GO:0008237	metallopeptidase activity
0.33	GO:0008146	sulfotransferase activity

0.43	GO:0005739	mitochondrion
0.36	GO:0070062	extracellular exosome

0.71

EC:3.4.11

GO:0004177

tr|T1FNM2|T1FNM2_HELRO
40S ribosomal protein S12
Search

RPS12

0.65	40S ribosomal protein S12

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0010243	response to organonitrogen compound
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.33	GO:0019083	viral transcription
0.33	GO:0016072	rRNA metabolic process
0.33	GO:0042254	ribosome biogenesis

0.64	GO:0003735	structural constituent of ribosome
0.33	GO:0003723	RNA binding

0.61	GO:0005840	ribosome
0.47	GO:0044445	cytosolic part
0.42	GO:0005794	Golgi apparatus
0.41	GO:0044446	intracellular organelle part
0.33	GO:0043233	organelle lumen
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|T1FNM3|T1FNM3_HELRO
Uncharacterized protein
Search

0.81	Transcriptional activator protein Pur-alpha

0.69

GO:0031935

regulation of chromatin silencing

0.62	GO:0003729	mRNA binding
0.55	GO:0043565	sequence-specific DNA binding
0.38	GO:0042802	identical protein binding
0.38	GO:0004019	adenylosuccinate synthase activity

0.73	GO:1990124	messenger ribonucleoprotein complex
0.52	GO:0005634	nucleus
0.43	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.38	EC:6.3.4.4	GO:0004019
0.38	KEGG:R01135	GO:0004019

tr|T1FNM4|T1FNM4_HELRO
Uncharacterized protein
Search

0.75	Proteasome activator complex subunit

0.45	GO:0010950	positive regulation of endopeptidase activity
0.45	GO:2000045	regulation of G1/S transition of mitotic cell cycle
0.44	GO:0061136	regulation of proteasomal protein catabolic process
0.41	GO:0010951	negative regulation of endopeptidase activity
0.34	GO:0000398	mRNA splicing, via spliceosome

0.47	GO:0061133	endopeptidase activator activity
0.41	GO:0004866	endopeptidase inhibitor activity

0.85	GO:0008537	proteasome activator complex
0.44	GO:0005703	polytene chromosome puff
0.44	GO:0005705	polytene chromosome interband
0.38	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016020	membrane

tr|T1FNM5|T1FNM5_HELRO
Uncharacterized protein
Search

PCCB

0.89	Propionyl Coenzyme A carboxylase, beta polypeptide

0.44

GO:0009062

fatty acid catabolic process

0.62

GO:0016874

ligase activity

0.62

GO:0016874

tr|T1FNM6|T1FNM6_HELRO
Uncharacterized protein
Search

SLC37A2

0.82	Solute carrier family 37 (Glycerol-3-phosphate transporter), member 2

0.72	GO:0015760	glucose-6-phosphate transport
0.61	GO:0035435	phosphate ion transmembrane transport

0.74

GO:0061513

glucose 6-phosphate:inorganic phosphate antiporter activity

0.62	GO:0030176	integral component of endoplasmic reticulum membrane
0.41	GO:0070062	extracellular exosome

tr|T1FNM7|T1FNM7_HELRO
Uncharacterized protein
Search

0.77	GO:0030574	collagen catabolic process
0.61	GO:0006508	proteolysis
0.58	GO:0001503	ossification
0.53	GO:0022617	extracellular matrix disassembly
0.53	GO:0001501	skeletal system development
0.52	GO:0050900	leukocyte migration
0.51	GO:0003416	endochondral bone growth
0.50	GO:0031214	biomineral tissue development
0.49	GO:0009653	anatomical structure morphogenesis
0.49	GO:0061448	connective tissue development

0.70	GO:0004222	metalloendopeptidase activity
0.63	GO:0008270	zinc ion binding
0.51	GO:0005518	collagen binding
0.45	GO:0005509	calcium ion binding
0.41	GO:0042802	identical protein binding
0.37	GO:0004252	serine-type endopeptidase activity
0.36	GO:0001968	fibronectin binding
0.34	GO:0050750	low-density lipoprotein particle receptor binding
0.34	GO:0048306	calcium-dependent protein binding

0.74	GO:0031012	extracellular matrix
0.42	GO:0005615	extracellular space
0.37	GO:0005581	collagen trimer
0.35	GO:0046581	intercellular canaliculus
0.34	GO:1903561	extracellular vesicle
0.34	GO:1904724	tertiary granule lumen
0.34	GO:1904813	ficolin-1-rich granule lumen
0.34	GO:0005764	lysosome
0.33	GO:0005794	Golgi apparatus
0.30	GO:0016021	integral component of membrane

0.70

GO:0004222

tr|T1FNM8|T1FNM8_HELRO
Uncharacterized protein
Search

CTNNBL1

0.87	Catenin beta like 1

0.80	GO:0016445	somatic diversification of immunoglobulins
0.72	GO:0043065	positive regulation of apoptotic process
0.45	GO:0006915	apoptotic process
0.42	GO:0008380	RNA splicing
0.41	GO:0006397	mRNA processing

0.66

GO:0019899

enzyme binding

0.78	GO:0000974	Prp19 complex
0.76	GO:0005681	spliceosomal complex
0.65	GO:0005654	nucleoplasm
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|T1FNM9|T1FNM9_HELRO
Uncharacterized protein
Search

0.61	ADP-ribosylation factor

0.46	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.44	GO:1990386	mitotic cleavage furrow ingression
0.42	GO:1904748	regulation of apoptotic process involved in development
0.42	GO:0048259	regulation of receptor-mediated endocytosis
0.41	GO:0098586	cellular response to virus
0.41	GO:0048599	oocyte development
0.41	GO:0006878	cellular copper ion homeostasis
0.40	GO:0009792	embryo development ending in birth or egg hatching
0.40	GO:0015031	protein transport
0.39	GO:0007005	mitochondrion organization

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0019904	protein domain specific binding
0.39	GO:0046982	protein heterodimerization activity
0.37	GO:0000287	magnesium ion binding
0.33	GO:0005102	receptor binding
0.33	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.33	GO:0003924	GTPase activity

0.46	GO:0005794	Golgi apparatus
0.41	GO:0030017	sarcomere
0.41	GO:0031252	cell leading edge
0.38	GO:0005783	endoplasmic reticulum
0.38	GO:0005829	cytosol
0.38	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0043234	protein complex
0.36	GO:0070062	extracellular exosome
0.34	GO:0005578	proteinaceous extracellular matrix
0.33	GO:0098588	bounding membrane of organelle

0.33

GO:0003755

tr|T1FNN0|T1FNN0_HELRO
Uncharacterized protein
Search

0.70	GO:0016567	protein ubiquitination
0.57	GO:2000042	negative regulation of double-strand break repair via homologous recombination
0.56	GO:0071630	nuclear protein quality control by the ubiquitin-proteasome system
0.41	GO:0009888	tissue development
0.41	GO:0048646	anatomical structure formation involved in morphogenesis
0.41	GO:0048468	cell development
0.41	GO:0048513	animal organ development
0.40	GO:0014902	myotube differentiation
0.40	GO:0031032	actomyosin structure organization
0.39	GO:0022607	cellular component assembly

0.45	GO:0004842	ubiquitin-protein transferase activity
0.37	GO:0042802	identical protein binding
0.37	GO:0003676	nucleic acid binding

0.79	GO:0031463	Cul3-RING ubiquitin ligase complex
0.44	GO:0005634	nucleus
0.38	GO:0030127	COPII vesicle coat
0.37	GO:0005815	microtubule organizing center
0.37	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

0.45

GO:0004842

tr|T1FNN1|T1FNN1_HELRO
Uncharacterized protein
Search

NDUFS8

0.45	NADH-quinone oxidoreductase subunit NuoI

0.53	GO:0055114	oxidation-reduction process
0.37	GO:0032981	mitochondrial respiratory chain complex I assembly
0.35	GO:0006979	response to oxidative stress

0.67	GO:0051539	4 iron, 4 sulfur cluster binding
0.67	GO:0016651	oxidoreductase activity, acting on NAD(P)H
0.54	GO:0048038	quinone binding
0.50	GO:0005506	iron ion binding

0.46	GO:0005886	plasma membrane
0.37	GO:0005747	mitochondrial respiratory chain complex I

0.67

EC:1.6

GO:0016651

tr|T1FNN2|T1FNN2_HELRO
Uncharacterized protein
Search

HSP60

0.64	Heat shock protein, mitochondrial

0.76	GO:0042026	protein refolding
0.47	GO:0009409	response to cold
0.44	GO:0000413	protein peptidyl-prolyl isomerization
0.41	GO:0006986	response to unfolded protein
0.40	GO:0002368	B cell cytokine production
0.40	GO:0048291	isotype switching to IgG isotypes
0.40	GO:0002842	positive regulation of T cell mediated immune response to tumor cell
0.40	GO:0032727	positive regulation of interferon-alpha production
0.39	GO:0007005	mitochondrion organization
0.39	GO:0032729	positive regulation of interferon-gamma production

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.39	GO:0034186	apolipoprotein A-I binding
0.39	GO:0008035	high-density lipoprotein particle binding
0.38	GO:0044183	protein binding involved in protein folding
0.38	GO:0002039	p53 binding
0.37	GO:0031625	ubiquitin protein ligase binding

0.49	GO:0005737	cytoplasm
0.39	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex
0.39	GO:0043209	myelin sheath
0.38	GO:0046696	lipopolysaccharide receptor complex
0.38	GO:0070062	extracellular exosome
0.38	GO:0005905	clathrin-coated pit
0.37	GO:0097708	intracellular vesicle
0.37	GO:0009986	cell surface
0.37	GO:0070013	intracellular organelle lumen
0.35	GO:0019866	organelle inner membrane

0.44

GO:0003755

tr|T1FNN3|T1FNN3_HELRO
Importin subunit alpha
Search

KPNA3

0.60	Importin subunit alpha

0.80	GO:0006606	protein import into nucleus
0.37	GO:0042542	response to hydrogen peroxide
0.35	GO:0016125	sterol metabolic process
0.34	GO:1902594	multi-organism nuclear import
0.34	GO:0075733	intracellular transport of virus
0.33	GO:0044068	modulation by symbiont of host cellular process
0.33	GO:0006461	protein complex assembly
0.33	GO:0019048	modulation by virus of host morphology or physiology
0.33	GO:0051806	entry into cell of other organism involved in symbiotic interaction
0.33	GO:0044409	entry into host

0.83	GO:0061608	nuclear import signal receptor activity
0.66	GO:0008565	protein transporter activity
0.52	GO:0008022	protein C-terminus binding
0.46	GO:0008139	nuclear localization sequence binding
0.36	GO:0047750	cholestenol delta-isomerase activity

0.61	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.42	GO:0012505	endomembrane system
0.41	GO:0031974	membrane-enclosed lumen
0.40	GO:0031967	organelle envelope
0.39	GO:0043234	protein complex
0.34	GO:0031090	organelle membrane
0.33	GO:0044216	other organism cell
0.33	GO:0018995	host
0.30	GO:0016021	integral component of membrane

0.36

EC:5.3.3.5

GO:0047750

tr|T1FNN4|T1FNN4_HELRO
4-hydroxyphenylpyruvate dioxygenase
Search

0.56	4-hydroxyphenylpyruvate dioxygenase

0.69	GO:0009072	aromatic amino acid family metabolic process
0.53	GO:0055114	oxidation-reduction process
0.40	GO:1901606	alpha-amino acid catabolic process
0.39	GO:1901361	organic cyclic compound catabolic process
0.39	GO:0019439	aromatic compound catabolic process
0.37	GO:1902221	erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process
0.36	GO:0042737	drug catabolic process
0.34	GO:0071103	DNA conformation change
0.34	GO:0006333	chromatin assembly or disassembly
0.34	GO:0034728	nucleosome organization

0.82	GO:0003868	4-hydroxyphenylpyruvate dioxygenase activity
0.52	GO:0046872	metal ion binding
0.43	GO:0004462	lactoylglutathione lyase activity
0.33	GO:0003678	DNA helicase activity
0.33	GO:0003677	DNA binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.41	GO:0000139	Golgi membrane
0.41	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0070062	extracellular exosome
0.33	GO:0000786	nucleosome
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.82	EC:1.13.11.27	GO:0003868
0.43	KEGG:R02530	GO:0004462

tr|T1FNN5|T1FNN5_HELRO
Uncharacterized protein
Search

PMPCA

0.83	Mitochondrial-processing peptidase subunit alpha

0.83	GO:0006627	protein processing involved in protein targeting to mitochondrion
0.34	GO:0006420	arginyl-tRNA aminoacylation
0.33	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic

0.67	GO:0004222	metalloendopeptidase activity
0.54	GO:0046872	metal ion binding
0.34	GO:0016844	strictosidine synthase activity
0.34	GO:0004814	arginine-tRNA ligase activity
0.33	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0030554	adenyl nucleotide binding

0.61	GO:0005739	mitochondrion
0.41	GO:0019866	organelle inner membrane
0.33	GO:0031974	membrane-enclosed lumen

0.67	EC:3.4.24	GO:0004222
0.34	KEGG:R03738	GO:0016844

tr|T1FNN6|T1FNN6_HELRO
Uncharacterized protein
Search

PHF5A

0.80	PHD finger domain-containing protein 5A

0.74	GO:0000398	mRNA splicing, via spliceosome
0.44	GO:0045893	positive regulation of transcription, DNA-templated
0.38	GO:0006351	transcription, DNA-templated

0.40	GO:0003700	DNA binding transcription factor activity
0.38	GO:0003723	RNA binding
0.37	GO:0003677	DNA binding
0.37	GO:0046872	metal ion binding
0.35	GO:0005515	protein binding

0.85	GO:0005689	U12-type spliceosomal complex
0.82	GO:0005686	U2 snRNP
0.73	GO:0016363	nuclear matrix
0.72	GO:0071011	precatalytic spliceosome
0.70	GO:0071013	catalytic step 2 spliceosome
0.69	GO:0016607	nuclear speck
0.40	GO:0005730	nucleolus
0.30	GO:0031224	intrinsic component of membrane

tr|T1FNN7|T1FNN7_HELRO
Uncharacterized protein
Search

0.78	GO:0032786	positive regulation of DNA-templated transcription, elongation
0.78	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.74	GO:0051028	mRNA transport
0.73	GO:0006405	RNA export from nucleus
0.73	GO:0046784	viral mRNA export from host cell nucleus
0.72	GO:2000002	negative regulation of DNA damage checkpoint
0.72	GO:0030224	monocyte differentiation
0.53	GO:0010467	gene expression
0.48	GO:0045650	negative regulation of macrophage differentiation
0.48	GO:2000035	regulation of stem cell division

0.63	GO:0003729	mRNA binding
0.39	GO:0005515	protein binding

0.83	GO:0000445	THO complex part of transcription export complex
0.71	GO:0000228	nuclear chromosome
0.64	GO:0000781	chromosome, telomeric region
0.58	GO:0005654	nucleoplasm
0.36	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|T1FNN8|T1FNN8_HELRO
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial
Search

SUCLG1

0.85	Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial

0.68	GO:0006099	tricarboxylic acid cycle
0.35	GO:0006104	succinyl-CoA metabolic process
0.34	GO:0006105	succinate metabolic process
0.34	GO:0043043	peptide biosynthetic process
0.33	GO:0044267	cellular protein metabolic process
0.33	GO:0010467	gene expression
0.33	GO:0009059	macromolecule biosynthetic process

0.85	GO:0004776	succinate-CoA ligase (GDP-forming) activity
0.75	GO:0004775	succinate-CoA ligase (ADP-forming) activity
0.55	GO:0048037	cofactor binding
0.51	GO:1901265	nucleoside phosphate binding
0.50	GO:0036094	small molecule binding
0.34	GO:0019843	rRNA binding
0.34	GO:0003735	structural constituent of ribosome
0.34	GO:0046982	protein heterodimerization activity
0.33	GO:0016829	lyase activity
0.32	GO:0097367	carbohydrate derivative binding

0.59	GO:0005739	mitochondrion
0.41	GO:0005829	cytosol
0.39	GO:0031974	membrane-enclosed lumen
0.38	GO:0044446	intracellular organelle part
0.38	GO:0031090	organelle membrane
0.37	GO:0031975	envelope
0.37	GO:0005886	plasma membrane
0.36	GO:0042709	succinate-CoA ligase complex
0.34	GO:0070062	extracellular exosome
0.34	GO:0005840	ribosome

0.85	EC:6.2.1.4	GO:0004776
0.85	KEGG:R00432	GO:0004776

tr|T1FNN9|T1FNN9_HELRO
Malate dehydrogenase
Search

0.46	Malate dehydrogenase

0.78	GO:0006108	malate metabolic process
0.70	GO:0006099	tricarboxylic acid cycle
0.60	GO:0005975	carbohydrate metabolic process
0.45	GO:0006734	NADH metabolic process
0.44	GO:0006107	oxaloacetate metabolic process

0.79

GO:0030060

L-malate dehydrogenase activity

0.43	GO:0043209	myelin sheath
0.40	GO:0005829	cytosol
0.40	GO:0005739	mitochondrion
0.35	GO:0042579	microbody
0.33	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

0.79

EC:1.1.1.37

GO:0030060

tr|T1FNP0|T1FNP0_HELRO
Uncharacterized protein
Search

FTCD

0.76	Glutamate formiminotransferase / formiminotetrahydrofolate cyclodeaminase

0.39	GO:0019557	histidine catabolic process to glutamate and formate
0.39	GO:0043606	formamide metabolic process
0.38	GO:0035999	tetrahydrofolate interconversion
0.36	GO:0007010	cytoskeleton organization
0.33	GO:0006352	DNA-templated transcription, initiation
0.33	GO:0015074	DNA integration
0.33	GO:0006310	DNA recombination

0.84	GO:0005542	folic acid binding
0.51	GO:0016740	transferase activity
0.48	GO:0008017	microtubule binding
0.43	GO:0030412	formimidoyltetrahydrofolate cyclodeaminase activity
0.35	GO:0019215	intermediate filament binding
0.33	GO:0016866	intramolecular transferase activity
0.33	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity
0.32	GO:0003677	DNA binding

0.55	GO:0030868	smooth endoplasmic reticulum membrane
0.50	GO:0005794	Golgi apparatus
0.46	GO:0005829	cytosol
0.40	GO:0005886	plasma membrane
0.39	GO:0005814	centriole
0.37	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.36	GO:0070062	extracellular exosome

0.51	EC:2	GO:0016740
0.43	KEGG:R02302	GO:0030412

tr|T1FNP1|T1FNP1_HELRO
Uncharacterized protein
Search

0.30

GO:0044425

membrane part

tr|T1FNP2|T1FNP2_HELRO
Uncharacterized protein
Search

tr|T1FNP3|T1FNP3_HELRO
Uncharacterized protein
Search

DDC

0.61	Aromatic-L-amino-acid decarboxylase

0.60	GO:0006520	cellular amino acid metabolic process
0.39	GO:0046189	phenol-containing compound biosynthetic process
0.39	GO:0046333	octopamine metabolic process
0.38	GO:0042136	neurotransmitter biosynthetic process
0.38	GO:0007420	brain development
0.37	GO:0009636	response to toxic substance
0.37	GO:0033076	isoquinoline alkaloid metabolic process
0.37	GO:0042401	cellular biogenic amine biosynthetic process
0.37	GO:0015842	aminergic neurotransmitter loading into synaptic vesicle
0.37	GO:0052314	phytoalexin metabolic process

0.68	GO:0016831	carboxy-lyase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.38	GO:0019899	enzyme binding
0.35	GO:0019904	protein domain specific binding
0.35	GO:0016597	amino acid binding
0.33	GO:0016491	oxidoreductase activity
0.33	GO:0008483	transaminase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.39	GO:0043025	neuronal cell body
0.39	GO:0030424	axon
0.36	GO:0008021	synaptic vesicle
0.34	GO:0070062	extracellular exosome
0.33	GO:0005829	cytosol

0.68

EC:4.1.1

GO:0016831

tr|T1FNP4|T1FNP4_HELRO
Uncharacterized protein
Search

0.76

GO:0030261

chromosome condensation

tr|T1FNP5|T1FNP5_HELRO
Uncharacterized protein
Search

0.84	Glycerol-3-phosphate acyltransferase 3

0.42	GO:0002071	glandular epithelial cell maturation
0.41	GO:0046339	diacylglycerol metabolic process
0.41	GO:0019432	triglyceride biosynthetic process
0.40	GO:0040014	regulation of multicellular organism growth
0.40	GO:0006656	phosphatidylcholine biosynthetic process
0.38	GO:0035383	thioester metabolic process
0.37	GO:0006631	fatty acid metabolic process
0.36	GO:0006732	coenzyme metabolic process
0.36	GO:0007595	lactation
0.35	GO:0016024	CDP-diacylglycerol biosynthetic process

0.63	GO:0016746	transferase activity, transferring acyl groups
0.33	GO:0003743	translation initiation factor activity
0.33	GO:0005215	transporter activity

0.40	GO:0005783	endoplasmic reticulum
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.63

EC:2.3

GO:0016746

tr|T1FNP6|T1FNP6_HELRO
Uncharacterized protein
Search

RPS2

0.88	Ribosomal protein S2-like isoform 3

0.60	GO:0006412	translation
0.40	GO:0071353	cellular response to interleukin-4

0.64	GO:0003735	structural constituent of ribosome
0.59	GO:0003723	RNA binding

0.70

GO:0015935

small ribosomal subunit

tr|T1FNP7|T1FNP7_HELRO
Uncharacterized protein
Search

MFAP1

0.81	Microfibrillar-associated protein (Fragment)

tr|T1FNP8|T1FNP8_HELRO
Uncharacterized protein
Search

PSMD3

0.87	26S proteasome non-ATPase regulatory subunit 3

0.75	GO:0042176	regulation of protein catabolic process
0.66	GO:0050790	regulation of catalytic activity
0.46	GO:0008345	larval locomotory behavior
0.45	GO:0071599	otic vesicle development
0.43	GO:0006511	ubiquitin-dependent protein catabolic process
0.43	GO:0007420	brain development
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation

0.68	GO:0030234	enzyme regulator activity
0.34	GO:0005515	protein binding

0.70	GO:1905369	endopeptidase complex
0.58	GO:0043234	protein complex
0.44	GO:0005622	intracellular
0.36	GO:0070062	extracellular exosome
0.35	GO:0031983	vesicle lumen
0.34	GO:0012505	endomembrane system
0.30	GO:0016020	membrane

tr|T1FNP9|T1FNP9_HELRO
Uncharacterized protein
Search

BPNT1

0.52	Biphosphate nucleotidase

0.75	GO:0046854	phosphatidylinositol phosphorylation
0.36	GO:0016311	dephosphorylation

0.38	GO:0008441	3'(2'),5'-bisphosphate nucleotidase activity
0.35	GO:0004441	inositol-1,4-bisphosphate 1-phosphatase activity
0.33	GO:0000287	magnesium ion binding

0.34	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.38

EC:3.1.3.7

GO:0008441

tr|T1FNQ0|T1FNQ0_HELRO
Uncharacterized protein
Search

0.61	Heat shock 70 kDa protein cognate

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.30	GO:0044425	membrane part
0.30	GO:0005623	cell

tr|T1FNQ1|T1FNQ1_HELRO
Uncharacterized protein
Search

GAA

0.84	Lysosomal alpha-glucosidase

0.60	GO:0005975	carbohydrate metabolic process
0.55	GO:0043181	vacuolar sequestering
0.54	GO:0002086	diaphragm contraction
0.53	GO:0050884	neuromuscular process controlling posture
0.53	GO:0002026	regulation of the force of heart contraction
0.52	GO:0046716	muscle cell cellular homeostasis
0.52	GO:0060048	cardiac muscle contraction
0.52	GO:0050885	neuromuscular process controlling balance
0.51	GO:0007040	lysosome organization
0.50	GO:0003007	heart morphogenesis

0.70	GO:0030246	carbohydrate binding
0.66	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.33	GO:0051539	4 iron, 4 sulfur cluster binding
0.33	GO:0046872	metal ion binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0003677	DNA binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.49	GO:0005764	lysosome
0.38	GO:0098852	lytic vacuole membrane
0.36	GO:0070062	extracellular exosome
0.35	GO:0101003	ficolin-1-rich granule membrane
0.35	GO:0070821	tertiary granule membrane
0.35	GO:0005775	vacuolar lumen
0.32	GO:0005634	nucleus
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.66

EC:3.2.1

GO:0004553

tr|T1FNQ2|T1FNQ2_HELRO
Uncharacterized protein
Search

tr|T1FNQ3|T1FNQ3_HELRO
Tubulin beta chain
Search

0.56	Tubulin beta chain

0.72	GO:0007017	microtubule-based process
0.71	GO:0007010	cytoskeleton organization
0.38	GO:0060271	cilium assembly
0.35	GO:0042267	natural killer cell mediated cytotoxicity
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0000086	G2/M transition of mitotic cell cycle
0.34	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.34	GO:0140056	organelle localization by membrane tethering
0.34	GO:0016567	protein ubiquitination

0.77	GO:0005200	structural constituent of cytoskeleton
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.65	GO:0032561	guanyl ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0003725	double-stranded RNA binding
0.35	GO:0042288	MHC class I protein binding
0.34	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0051082	unfolded protein binding
0.33	GO:0008270	zinc ion binding

0.73	GO:0005874	microtubule
0.47	GO:0043209	myelin sheath
0.46	GO:0005737	cytoplasm
0.36	GO:0031012	extracellular matrix
0.36	GO:0070062	extracellular exosome
0.35	GO:0045298	tubulin complex
0.35	GO:0031983	vesicle lumen
0.34	GO:0030496	midbody
0.34	GO:0005634	nucleus
0.34	GO:0097708	intracellular vesicle

0.34

GO:0004842

tr|T1FNQ4|T1FNQ4_HELRO
Uncharacterized protein
Search

PGGT1B

0.79	LOW QUALITY PROTEIN: geranylgeranyl transferase type-1 subunit beta

0.56	GO:0018344	protein geranylgeranylation
0.46	GO:0001955	blood vessel maturation
0.39	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process
0.37	GO:0045787	positive regulation of cell cycle
0.37	GO:0008284	positive regulation of cell proliferation
0.37	GO:0034097	response to cytokine
0.36	GO:0035050	embryonic heart tube development

0.57	GO:0004661	protein geranylgeranyltransferase activity
0.37	GO:0019840	isoprenoid binding
0.37	GO:0042277	peptide binding
0.35	GO:0008270	zinc ion binding
0.33	GO:0008144	drug binding
0.33	GO:0005515	protein binding

0.59	GO:0005953	CAAX-protein geranylgeranyltransferase complex
0.30	GO:0016020	membrane

0.57

EC:2.5.1

GO:0004661

tr|T1FNQ5|T1FNQ5_HELRO
Uncharacterized protein
Search

DGAT2

0.84	Monoacylglycerol acyltransferase

0.54	GO:0035356	cellular triglyceride homeostasis
0.54	GO:0071400	cellular response to oleic acid
0.54	GO:0060613	fat pad development
0.54	GO:0046339	diacylglycerol metabolic process
0.53	GO:0034383	low-density lipoprotein particle clearance
0.53	GO:0055089	fatty acid homeostasis
0.52	GO:0035336	long-chain fatty-acyl-CoA metabolic process
0.52	GO:0019432	triglyceride biosynthetic process
0.52	GO:0019915	lipid storage
0.51	GO:0042632	cholesterol homeostasis

0.64	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
0.47	GO:0042803	protein homodimerization activity
0.38	GO:0003924	GTPase activity
0.38	GO:0032550	purine ribonucleoside binding
0.38	GO:0019001	guanyl nucleotide binding
0.35	GO:0032555	purine ribonucleotide binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0050662	coenzyme binding

0.51	GO:0005811	lipid droplet
0.49	GO:0048471	perinuclear region of cytoplasm
0.48	GO:0030176	integral component of endoplasmic reticulum membrane
0.42	GO:0005739	mitochondrion

0.64

GO:0016747

tr|T1FNQ6|T1FNQ6_HELRO
Uncharacterized protein
Search

0.50	Adenine nucleotide translocator

0.55	GO:0055085	transmembrane transport
0.47	GO:0015866	ADP transport
0.47	GO:0015867	ATP transport
0.45	GO:0006839	mitochondrial transport
0.42	GO:0090559	regulation of membrane permeability
0.41	GO:0007006	mitochondrial membrane organization
0.34	GO:0015074	DNA integration

0.56	GO:0022857	transmembrane transporter activity
0.32	GO:0003676	nucleic acid binding

0.61	GO:0019866	organelle inner membrane
0.61	GO:0031966	mitochondrial membrane
0.30	GO:0031224	intrinsic component of membrane

tr|T1FNQ7|T1FNQ7_HELRO
Uncharacterized protein
Search

CCT7

0.73	Chaperonin-containing T-complex polypeptide eta subunit

0.69	GO:0006457	protein folding
0.50	GO:1904869	regulation of protein localization to Cajal body
0.50	GO:1904851	positive regulation of establishment of protein localization to telomere
0.49	GO:1904874	positive regulation of telomerase RNA localization to Cajal body
0.48	GO:0032212	positive regulation of telomere maintenance via telomerase
0.47	GO:1900182	positive regulation of protein localization to nucleus
0.47	GO:0007339	binding of sperm to zona pellucida
0.46	GO:0050821	protein stabilization
0.45	GO:1901998	toxin transport
0.34	GO:0060079	excitatory postsynaptic potential

0.71	GO:0051082	unfolded protein binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0044183	protein binding involved in protein folding
0.43	GO:0042802	identical protein binding
0.34	GO:0005234	extracellularly glutamate-gated ion channel activity
0.34	GO:0004970	ionotropic glutamate receptor activity
0.32	GO:0003677	DNA binding

0.52	GO:0005832	chaperonin-containing T-complex
0.48	GO:0002199	zona pellucida receptor complex
0.45	GO:0044297	cell body
0.44	GO:0005874	microtubule
0.39	GO:0005739	mitochondrion
0.36	GO:0070062	extracellular exosome
0.34	GO:0098794	postsynapse
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

tr|T1FNQ8|T1FNQ8_HELRO
Uncharacterized protein
Search

SLC13A2

0.64	Solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2

0.73	GO:0006814	sodium ion transport
0.55	GO:0055085	transmembrane transport
0.44	GO:0006820	anion transport
0.42	GO:0072348	sulfur compound transport
0.38	GO:0015849	organic acid transport
0.38	GO:0008340	determination of adult lifespan
0.37	GO:0015893	drug transport
0.32	GO:0006351	transcription, DNA-templated
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.56	GO:0005215	transporter activity
0.33	GO:0043565	sequence-specific DNA binding
0.33	GO:0003700	DNA binding transcription factor activity

0.41	GO:0005887	integral component of plasma membrane
0.33	GO:0005634	nucleus

tr|T1FNQ9|T1FNQ9_HELRO
Uncharacterized protein
Search

CCNB3

0.56	G2/mitotic-specific cyclin-B3

0.78	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.77	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity
0.39	GO:0051321	meiotic cell cycle
0.38	GO:0035046	pronuclear migration
0.37	GO:1903047	mitotic cell cycle process
0.37	GO:0090068	positive regulation of cell cycle process
0.37	GO:0001556	oocyte maturation
0.37	GO:0007088	regulation of mitotic nuclear division
0.37	GO:0010638	positive regulation of organelle organization
0.37	GO:0051173	positive regulation of nitrogen compound metabolic process

0.75	GO:0019901	protein kinase binding
0.38	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity

0.61	GO:0005634	nucleus
0.37	GO:0031974	membrane-enclosed lumen
0.36	GO:0044446	intracellular organelle part
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.38

GO:0016538

tr|T1FNR0|T1FNR0_HELRO
Uncharacterized protein
Search

0.10	Snurportin-1 (Fragment)

0.74	GO:0006606	protein import into nucleus
0.62	GO:0061015	snRNA import into nucleus
0.42	GO:0006266	DNA ligation
0.42	GO:0006370	7-methylguanosine mRNA capping
0.39	GO:0006310	DNA recombination
0.39	GO:0006281	DNA repair
0.36	GO:0009745	sucrose mediated signaling
0.36	GO:0009731	detection of sucrose stimulus
0.35	GO:0051594	detection of glucose
0.35	GO:0010255	glucose mediated signaling pathway

0.76	GO:0061608	nuclear import signal receptor activity
0.45	GO:0008565	protein transporter activity
0.44	GO:0004484	mRNA guanylyltransferase activity
0.43	GO:0030620	U2 snRNA binding
0.43	GO:0030621	U4 snRNA binding
0.42	GO:0003910	DNA ligase (ATP) activity
0.42	GO:0030619	U1 snRNA binding
0.37	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0008144	drug binding

0.47	GO:0005634	nucleus
0.43	GO:0071254	cytoplasmic U snRNP body
0.38	GO:0031974	membrane-enclosed lumen
0.37	GO:0044446	intracellular organelle part
0.34	GO:0031461	cullin-RING ubiquitin ligase complex
0.33	GO:0005886	plasma membrane
0.32	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

0.44

EC:2.7.7.50

GO:0004484

tr|T1FNR1|T1FNR1_HELRO
T-complex protein 1 subunit delta
Search

CCT4

0.70	T-complex protein 1 subunit delta

0.69	GO:0006457	protein folding
0.42	GO:0090670	RNA localization to Cajal body
0.42	GO:1904869	regulation of protein localization to Cajal body
0.42	GO:1904851	positive regulation of establishment of protein localization to telomere
0.42	GO:1904874	positive regulation of telomerase RNA localization to Cajal body
0.42	GO:0001666	response to hypoxia
0.41	GO:0051973	positive regulation of telomerase activity
0.41	GO:0007339	binding of sperm to zona pellucida
0.41	GO:0032212	positive regulation of telomere maintenance via telomerase
0.40	GO:1900182	positive regulation of protein localization to nucleus

0.71	GO:0051082	unfolded protein binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0044183	protein binding involved in protein folding
0.33	GO:0003723	RNA binding
0.32	GO:0016740	transferase activity

0.47	GO:0005737	cytoplasm
0.46	GO:0101031	chaperone complex
0.42	GO:0002199	zona pellucida receptor complex
0.40	GO:0044297	cell body
0.39	GO:0005813	centrosome
0.38	GO:0005874	microtubule
0.38	GO:0005654	nucleoplasm
0.35	GO:0005929	cilium
0.35	GO:0097708	intracellular vesicle
0.34	GO:0070062	extracellular exosome

0.32

GO:0016740

tr|T1FNR2|T1FNR2_HELRO
Uncharacterized protein
Search

UBE2L3

0.59	Ubiquitin-conjugating enzyme

0.49	GO:0000209	protein polyubiquitination
0.47	GO:0071385	cellular response to glucocorticoid stimulus
0.46	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.46	GO:1903955	positive regulation of protein targeting to mitochondrion
0.46	GO:0044770	cell cycle phase transition
0.45	GO:0051443	positive regulation of ubiquitin-protein transferase activity
0.45	GO:0008283	cell proliferation
0.38	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.38	GO:1903506	regulation of nucleic acid-templated transcription
0.38	GO:0010468	regulation of gene expression

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0061631	ubiquitin conjugating enzyme activity
0.47	GO:0031625	ubiquitin protein ligase binding
0.45	GO:0097027	ubiquitin-protein transferase activator activity
0.45	GO:0003713	transcription coactivator activity
0.40	GO:0016874	ligase activity
0.33	GO:0003723	RNA binding

0.40	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm
0.35	GO:0070062	extracellular exosome
0.34	GO:0098793	presynapse
0.34	GO:0000151	ubiquitin ligase complex
0.33	GO:0043233	organelle lumen
0.32	GO:0044446	intracellular organelle part

0.40

GO:0016874

tr|T1FNR3|T1FNR3_HELRO
Uncharacterized protein
Search

DARS

0.49	Aspartyl-tRNA synthetase

0.79	GO:0006422	aspartyl-tRNA aminoacylation
0.37	GO:0040007	growth
0.33	GO:0006461	protein complex assembly

0.79	GO:0004815	aspartate-tRNA ligase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0003676	nucleic acid binding
0.34	GO:0004046	aminoacylase activity
0.33	GO:0005515	protein binding

0.55	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex
0.49	GO:0005737	cytoplasm
0.34	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.79

EC:6.1.1.12

GO:0004815

tr|T1FNR4|T1FNR4_HELRO
Uncharacterized protein
Search

SRM

0.49	Spermidine synthase

0.76	GO:0006596	polyamine biosynthetic process
0.51	GO:0008216	spermidine metabolic process
0.47	GO:1990830	cellular response to leukemia inhibitory factor
0.39	GO:0055114	oxidation-reduction process
0.36	GO:0001867	complement activation, lectin pathway
0.35	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.35	GO:0006396	RNA processing
0.34	GO:0010469	regulation of receptor activity
0.34	GO:0006468	protein phosphorylation
0.33	GO:0006508	proteolysis

0.51	GO:0016740	transferase activity
0.45	GO:0042803	protein homodimerization activity
0.39	GO:0016491	oxidoreductase activity
0.37	GO:0008408	3'-5' exonuclease activity
0.35	GO:0005179	hormone activity
0.34	GO:0044877	macromolecular complex binding
0.34	GO:0005509	calcium ion binding
0.34	GO:0140096	catalytic activity, acting on a protein
0.34	GO:0017171	serine hydrolase activity
0.34	GO:0003676	nucleic acid binding

0.38	GO:0000176	nuclear exosome (RNase complex)
0.34	GO:0005576	extracellular region
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.51

GO:0016740

tr|T1FNR5|T1FNR5_HELRO
Uncharacterized protein
Search

tr|T1FNR6|T1FNR6_HELRO
Uncharacterized protein
Search

0.57	GO:1902775	mitochondrial large ribosomal subunit assembly
0.47	GO:0010501	RNA secondary structure unwinding
0.41	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.33	GO:0009409	response to cold
0.33	GO:0006401	RNA catabolic process

0.58	GO:0004386	helicase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0003676	nucleic acid binding
0.45	GO:0008186	RNA-dependent ATPase activity
0.41	GO:0140098	catalytic activity, acting on RNA
0.34	GO:0008270	zinc ion binding

0.53	GO:0042645	mitochondrial nucleoid
0.51	GO:0035770	ribonucleoprotein granule
0.51	GO:0005730	nucleolus
0.46	GO:0005829	cytosol
0.37	GO:0032047	mitosome

tr|T1FNR7|T1FNR7_HELRO
Uncharacterized protein
Search

0.70	Guanine nucleotide-binding protein G alpha subunit

0.82

GO:0007188

adenylate cyclase-modulating G-protein coupled receptor signaling pathway

0.81	GO:0031683	G-protein beta/gamma-subunit complex binding
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.64	GO:0004871	signal transducer activity
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0001664	G-protein coupled receptor binding
0.34	GO:0046872	metal ion binding

0.44	GO:1905360	GTPase complex
0.43	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.40	GO:0030425	dendrite
0.40	GO:0044297	cell body
0.40	GO:0098797	plasma membrane protein complex
0.34	GO:0097730	non-motile cilium
0.30	GO:0016021	integral component of membrane

tr|T1FNR8|T1FNR8_HELRO
Uncharacterized protein
Search

RPL10

0.41	Ribosomal protein 10

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.47	GO:1990403	embryonic brain development
0.44	GO:0000027	ribosomal large subunit assembly
0.42	GO:0006417	regulation of translation
0.41	GO:0007283	spermatogenesis
0.41	GO:0007420	brain development
0.38	GO:0097421	liver regeneration

0.64	GO:0003735	structural constituent of ribosome
0.45	GO:0045182	translation regulator activity
0.38	GO:0003723	RNA binding
0.33	GO:0005515	protein binding
0.32	GO:0016787	hydrolase activity

0.61	GO:0005840	ribosome
0.45	GO:0044445	cytosolic part
0.44	GO:0005790	smooth endoplasmic reticulum
0.40	GO:0005844	polysome
0.40	GO:0044446	intracellular organelle part
0.39	GO:0005634	nucleus
0.34	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.32

GO:0016787

tr|T1FNR9|T1FNR9_HELRO
Uncharacterized protein
Search

0.66	Telomere length and silencing protein 1 homolog

0.40	GO:0072321	chaperone-mediated protein transport
0.40	GO:0045104	intermediate filament cytoskeleton organization
0.40	GO:0006998	nuclear envelope organization
0.39	GO:0048489	synaptic vesicle transport
0.38	GO:0061077	chaperone-mediated protein folding
0.38	GO:0031175	neuron projection development
0.37	GO:0007155	cell adhesion
0.34	GO:0016310	phosphorylation
0.33	GO:1901360	organic cyclic compound metabolic process
0.33	GO:0006725	cellular aromatic compound metabolic process

0.38	GO:0005515	protein binding
0.37	GO:0019205	nucleobase-containing compound kinase activity
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0003676	nucleic acid binding

0.68	GO:0005654	nucleoplasm
0.67	GO:0005829	cytosol
0.39	GO:0005788	endoplasmic reticulum lumen
0.38	GO:0005635	nuclear envelope
0.38	GO:0045202	synapse
0.30	GO:0016020	membrane

tr|T1FNS0|T1FNS0_HELRO
Uncharacterized protein
Search

THOC3

0.90	THO complex subunit 3

0.79	GO:0046784	viral mRNA export from host cell nucleus
0.77	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.73	GO:0051028	mRNA transport
0.72	GO:0006405	RNA export from nucleus
0.52	GO:0010467	gene expression
0.40	GO:0016071	mRNA metabolic process
0.40	GO:0031532	actin cytoskeleton reorganization
0.39	GO:0007155	cell adhesion
0.38	GO:0016573	histone acetylation
0.36	GO:0006457	protein folding

0.40	GO:0005515	protein binding
0.39	GO:0003723	RNA binding
0.38	GO:0004402	histone acetyltransferase activity
0.34	GO:0046872	metal ion binding

0.82	GO:0000445	THO complex part of transcription export complex
0.71	GO:0000784	nuclear chromosome, telomeric region
0.43	GO:0016607	nuclear speck
0.30	GO:0016020	membrane

0.38

GO:0004402

tr|T1FNS1|T1FNS1_HELRO
Transgelin
Search

0.10	Transgelin

0.79	GO:0031032	actomyosin structure organization
0.42	GO:0043535	regulation of blood vessel endothelial cell migration
0.42	GO:0045493	xylan catabolic process
0.41	GO:0043408	regulation of MAPK cascade

0.73	GO:0005516	calmodulin binding
0.73	GO:0003779	actin binding
0.39	GO:0016798	hydrolase activity, acting on glycosyl bonds

0.53

GO:0005856

cytoskeleton

0.39

EC:3.2

GO:0016798

tr|T1FNS2|T1FNS2_HELRO
Uncharacterized protein
Search

MOB4

0.91	Preimplantation protein 3

0.51	GO:0016310	phosphorylation
0.44	GO:0006457	protein folding
0.38	GO:0006900	vesicle budding from membrane
0.37	GO:0006479	protein methylation

0.53	GO:0016301	kinase activity
0.46	GO:0019900	kinase binding
0.39	GO:0032559	adenyl ribonucleotide binding
0.39	GO:0008144	drug binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0046872	metal ion binding
0.35	GO:0008168	methyltransferase activity

0.55	GO:0005794	Golgi apparatus
0.47	GO:0043197	dendritic spine
0.47	GO:0048471	perinuclear region of cytoplasm
0.46	GO:0043025	neuronal cell body
0.44	GO:0098588	bounding membrane of organelle
0.43	GO:0031984	organelle subcompartment
0.42	GO:0005829	cytosol

0.35

GO:0008168

tr|T1FNS3|T1FNS3_HELRO
Uncharacterized protein
Search

MRTO4

0.72	mRNA turnover protein 4 homolog

0.77	GO:0000027	ribosomal large subunit assembly
0.45	GO:0000956	nuclear-transcribed mRNA catabolic process
0.42	GO:0006364	rRNA processing

0.33	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.73	GO:0005730	nucleolus
0.48	GO:0005737	cytoplasm
0.35	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0031224	intrinsic component of membrane

tr|T1FNS4|T1FNS4_HELRO
Uncharacterized protein
Search

0.81

GO:0043130

ubiquitin binding

0.32	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

tr|T1FNS5|T1FNS5_HELRO
Uncharacterized protein
Search

GHITM

0.85	Growth hormone-inducible transmembrane protein-like

0.36	GO:0006915	apoptotic process
0.35	GO:1903507	negative regulation of nucleic acid-templated transcription

0.36	GO:0003714	transcription corepressor activity
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.33	GO:0005515	protein binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.39	GO:0005739	mitochondrion
0.36	GO:0070062	extracellular exosome
0.34	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

tr|T1FNS6|T1FNS6_HELRO
Uncharacterized protein
Search

0.62	UBX domain-containing protein 1-A

0.38	GO:0006891	intra-Golgi vesicle-mediated transport
0.35	GO:0001731	formation of translation preinitiation complex
0.35	GO:0006446	regulation of translational initiation
0.34	GO:0045665	negative regulation of neuron differentiation
0.34	GO:0007018	microtubule-based movement
0.34	GO:0043065	positive regulation of apoptotic process
0.34	GO:0070647	protein modification by small protein conjugation or removal
0.33	GO:0075525	viral translational termination-reinitiation
0.33	GO:0075522	IRES-dependent viral translational initiation
0.33	GO:0006357	regulation of transcription by RNA polymerase II

0.50	GO:0003676	nucleic acid binding
0.34	GO:0015631	tubulin binding
0.34	GO:0003777	microtubule motor activity
0.33	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.33	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.33	GO:0031625	ubiquitin protein ligase binding
0.32	GO:0008270	zinc ion binding
0.32	GO:0004842	ubiquitin-protein transferase activity
0.32	GO:0004930	G-protein coupled receptor activity
0.32	GO:0032559	adenyl ribonucleotide binding

0.38	GO:0030173	integral component of Golgi membrane
0.35	GO:0016282	eukaryotic 43S preinitiation complex
0.35	GO:0033290	eukaryotic 48S preinitiation complex
0.35	GO:0005852	eukaryotic translation initiation factor 3 complex
0.34	GO:0005634	nucleus
0.33	GO:0030015	CCR4-NOT core complex
0.33	GO:0010494	cytoplasmic stress granule
0.33	GO:0000151	ubiquitin ligase complex
0.32	GO:0005874	microtubule
0.32	GO:0005829	cytosol

0.32

GO:0004842

tr|T1FNS7|T1FNS7_HELRO
Uncharacterized protein
Search

SNRPB2

0.83	Small nuclear ribonucleoprotein polypeptide B''

0.43	GO:0000398	mRNA splicing, via spliceosome
0.36	GO:0070868	heterochromatin organization involved in chromatin silencing
0.36	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.36	GO:0048477	oogenesis

0.59	GO:0003723	RNA binding
0.39	GO:0070990	snRNP binding
0.36	GO:0005515	protein binding

0.59	GO:0019013	viral nucleocapsid
0.55	GO:0030529	intracellular ribonucleoprotein complex
0.50	GO:0001650	fibrillar center
0.50	GO:0120114	Sm-like protein family complex
0.49	GO:0016607	nuclear speck
0.42	GO:1902494	catalytic complex
0.33	GO:0043234	protein complex
0.30	GO:0016020	membrane

tr|T1FNS8|T1FNS8_HELRO
Uncharacterized protein
Search

0.65	N-acetyllactosaminide 3-alpha-galactosyltransferase

0.60	GO:0005975	carbohydrate metabolic process
0.40	GO:0045747	positive regulation of Notch signaling pathway
0.38	GO:0043413	macromolecule glycosylation
0.38	GO:0009101	glycoprotein biosynthetic process
0.37	GO:0009636	response to toxic substance
0.36	GO:0006464	cellular protein modification process

0.65	GO:0016757	transferase activity, transferring glycosyl groups
0.33	GO:0046872	metal ion binding
0.32	GO:0003723	RNA binding

0.30

GO:0044425

membrane part

0.65

EC:2.4

GO:0016757

tr|T1FNS9|T1FNS9_HELRO
Uncharacterized protein
Search

0.60	SAGA-associated factor 29 isoform X2

0.47	GO:0043966	histone H3 acetylation
0.37	GO:0071169	establishment of protein localization to chromatin
0.36	GO:0006351	transcription, DNA-templated
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:0010468	regulation of gene expression

0.48	GO:0140034	methylation-dependent protein binding
0.46	GO:0042393	histone binding
0.40	GO:0047485	protein N-terminus binding
0.38	GO:0019899	enzyme binding

0.80	GO:0000124	SAGA complex
0.48	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex

tr|T1FNT0|T1FNT0_HELRO
Uncharacterized protein
Search

ATP6V0B

0.97	ATPase H+ transporting V0 subunit b

0.76	GO:0015991	ATP hydrolysis coupled proton transport
0.51	GO:0048066	developmental pigmentation
0.51	GO:0060041	retina development in camera-type eye
0.50	GO:0007035	vacuolar acidification

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.48	GO:0036442	proton-exporting ATPase activity
0.45	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism

0.79	GO:0033179	proton-transporting V-type ATPase, V0 domain
0.58	GO:0005768	endosome
0.47	GO:0044437	vacuolar part
0.30	GO:0016021	integral component of membrane

tr|T1FNT1|T1FNT1_HELRO
Receptor expression-enhancing protein
Search

0.71	Receptor expression-enhancing protein 6

0.40	GO:0032386	regulation of intracellular transport
0.39	GO:0050908	detection of light stimulus involved in visual perception
0.34	GO:0048240	sperm capacitation
0.34	GO:0046464	acylglycerol catabolic process
0.33	GO:0043401	steroid hormone mediated signaling pathway
0.33	GO:0006418	tRNA aminoacylation for protein translation

0.34	GO:0047372	acylglycerol lipase activity
0.33	GO:0016875	ligase activity, forming carbon-oxygen bonds
0.33	GO:0140101	catalytic activity, acting on a tRNA
0.33	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.39	GO:0044317	rod spherule
0.39	GO:0012505	endomembrane system
0.39	GO:0001917	photoreceptor inner segment
0.37	GO:0045177	apical part of cell
0.37	GO:0031984	organelle subcompartment
0.35	GO:0043231	intracellular membrane-bounded organelle
0.35	GO:0044444	cytoplasmic part
0.34	GO:0097524	sperm plasma membrane
0.34	GO:0036126	sperm flagellum
0.30	GO:0016021	integral component of membrane

0.34

EC:3.1.1.23

GO:0047372

tr|T1FNT2|T1FNT2_HELRO
Uncharacterized protein
Search

0.76	Polyglutamine-binding protein 1

0.86	GO:0071360	cellular response to exogenous dsRNA
0.85	GO:0000380	alternative mRNA splicing, via spliceosome
0.85	GO:0002230	positive regulation of defense response to virus by host
0.85	GO:0032481	positive regulation of type I interferon production
0.84	GO:0048814	regulation of dendrite morphogenesis
0.80	GO:0002218	activation of innate immune response
0.79	GO:0043484	regulation of RNA splicing
0.78	GO:0031175	neuron projection development
0.76	GO:0051607	defense response to virus
0.53	GO:0045087	innate immune response

0.72	GO:0043021	ribonucleoprotein complex binding
0.71	GO:0003690	double-stranded DNA binding
0.41	GO:0008022	protein C-terminus binding
0.40	GO:0003713	transcription coactivator activity

0.87	GO:0071598	neuronal ribonucleoprotein granule
0.80	GO:0010494	cytoplasmic stress granule
0.80	GO:0016607	nuclear speck
0.67	GO:0005829	cytosol
0.41	GO:0097546	ciliary base
0.40	GO:0005813	centrosome

tr|T1FNT3|T1FNT3_HELRO
Uncharacterized protein
Search

0.93	Transmembrane protein 56-B

0.30

GO:0044425

membrane part

tr|T1FNT4|T1FNT4_HELRO
Uncharacterized protein
Search

ACSBG2

0.85	Long-chain-fatty-acid--CoA ligase 6

0.47	GO:0001676	long-chain fatty acid metabolic process
0.41	GO:0051384	response to glucocorticoid
0.40	GO:0000038	very long-chain fatty acid metabolic process
0.34	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process
0.33	GO:0007283	spermatogenesis
0.33	GO:0030154	cell differentiation
0.33	GO:0007275	multicellular organism development

0.52	GO:0016874	ligase activity
0.43	GO:0047617	acyl-CoA hydrolase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.40	GO:0005829	cytosol
0.38	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.52

GO:0016874

tr|T1FNT5|T1FNT5_HELRO
Transaldolase
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0.54	Transaldolase

0.73	GO:0006098	pentose-phosphate shunt
0.60	GO:0005975	carbohydrate metabolic process
0.34	GO:0006002	fructose 6-phosphate metabolic process
0.34	GO:0006635	fatty acid beta-oxidation

0.79	GO:0004801	sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity
0.34	GO:0003997	acyl-CoA oxidase activity
0.34	GO:0048029	monosaccharide binding
0.33	GO:0008081	phosphoric diester hydrolase activity
0.33	GO:0050660	flavin adenine dinucleotide binding

0.49	GO:0005737	cytoplasm
0.37	GO:0005654	nucleoplasm

0.79

EC:2.2.1.2

GO:0004801

tr|T1FNT6|T1FNT6_HELRO
Inosine-5'-monophosphate dehydrogenase
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0.54	Inosine-5'-monophosphate dehydrogenase

0.77	GO:0006177	GMP biosynthetic process
0.52	GO:0055114	oxidation-reduction process
0.51	GO:0046651	lymphocyte proliferation
0.44	GO:0006183	GTP biosynthetic process
0.39	GO:0071353	cellular response to interleukin-4
0.38	GO:0007623	circadian rhythm
0.37	GO:0001654	eye development
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0051289	protein homotetramerization
0.34	GO:0048066	developmental pigmentation

0.79	GO:0003938	IMP dehydrogenase activity
0.54	GO:0046872	metal ion binding
0.50	GO:1901265	nucleoside phosphate binding
0.49	GO:0036094	small molecule binding
0.39	GO:0003677	DNA binding
0.33	GO:0008168	methyltransferase activity
0.33	GO:0003723	RNA binding

0.56	GO:0005634	nucleus
0.47	GO:0005737	cytoplasm
0.35	GO:0031982	vesicle
0.34	GO:0005576	extracellular region
0.34	GO:0098805	whole membrane
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0044446	intracellular organelle part
0.33	GO:0012505	endomembrane system
0.33	GO:0031974	membrane-enclosed lumen

0.79

EC:1.1.1.205

GO:0003938

tr|T1FNT7|T1FNT7_HELRO
Uncharacterized protein
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RFC2

0.85	Replication factor C subunit 2

0.66	GO:0006260	DNA replication
0.53	GO:1900264	positive regulation of DNA-directed DNA polymerase activity
0.42	GO:0006281	DNA repair
0.35	GO:0042769	DNA damage response, detection of DNA damage
0.35	GO:1901796	regulation of signal transduction by p53 class mediator
0.34	GO:0071897	DNA biosynthetic process
0.34	GO:0000723	telomere maintenance
0.33	GO:0022402	cell cycle process
0.33	GO:0019725	cellular homeostasis
0.33	GO:0006310	DNA recombination

0.55	GO:0003689	DNA clamp loader activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0043142	single-stranded DNA-dependent ATPase activity
0.46	GO:0019899	enzyme binding
0.33	GO:0003887	DNA-directed DNA polymerase activity

0.55	GO:0005663	DNA replication factor C complex
0.51	GO:0031390	Ctf18 RFC-like complex
0.41	GO:0005634	nucleus
0.34	GO:0043233	organelle lumen

0.33

GO:0003887

tr|T1FNT8|T1FNT8_HELRO
Mitochondrial pyruvate carrier
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0.61	Mitochondrial pyruvate carrier

0.84	GO:0006850	mitochondrial pyruvate transmembrane transport
0.41	GO:0061732	mitochondrial acetyl-CoA biosynthetic process from pyruvate
0.39	GO:1990830	cellular response to leukemia inhibitory factor
0.34	GO:0097502	mannosylation

0.52	GO:0050833	pyruvate transmembrane transporter activity
0.35	GO:0019187	beta-1,4-mannosyltransferase activity
0.32	GO:0003676	nucleic acid binding

0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.46	GO:0031301	integral component of organelle membrane

0.35

EC:2.4.1

GO:0019187

tr|T1FNT9|T1FNT9_HELRO
Uncharacterized protein
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tr|T1FNU0|T1FNU0_HELRO
Uncharacterized protein
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TXNDC17

0.58	thioredoxin domain-containing protein 17

0.85	GO:0033209	tumor necrosis factor-mediated signaling pathway
0.69	GO:0098869	cellular oxidant detoxification
0.53	GO:0055114	oxidation-reduction process

0.82	GO:0047134	protein-disulfide reductase activity
0.72	GO:0004601	peroxidase activity

0.69

GO:0005829

cytosol

0.82	EC:1.8.1.8	GO:0047134
0.72	KEGG:R03532	GO:0004601

tr|T1FNU1|T1FNU1_HELRO
Uncharacterized protein
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ETFA

0.42	Electron transfer flavoprotein alpha subunit

0.60	GO:0022900	electron transport chain
0.50	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase
0.45	GO:0048567	ectodermal digestive tract morphogenesis
0.44	GO:0008258	head involution
0.44	GO:0007443	Malpighian tubule morphogenesis
0.43	GO:0007424	open tracheal system development
0.33	GO:0006119	oxidative phosphorylation
0.33	GO:0045333	cellular respiration

0.66	GO:0050660	flavin adenine dinucleotide binding
0.62	GO:0009055	electron transfer activity
0.34	GO:0005515	protein binding

0.43	GO:0005739	mitochondrion
0.37	GO:0045251	electron transfer flavoprotein complex
0.37	GO:0031974	membrane-enclosed lumen
0.36	GO:0070062	extracellular exosome
0.35	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

tr|T1FNU2|T1FNU2_HELRO
Uncharacterized protein
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CDK10

0.73	Cell division protein kinase

0.63	GO:0006468	protein phosphorylation
0.51	GO:1902018	negative regulation of cilium assembly
0.49	GO:0018210	peptidyl-threonine modification
0.48	GO:0051726	regulation of cell cycle
0.47	GO:0043410	positive regulation of MAPK cascade
0.46	GO:0032956	regulation of actin cytoskeleton organization
0.41	GO:0051301	cell division
0.35	GO:0030030	cell projection organization
0.34	GO:0043524	negative regulation of neuron apoptotic process
0.34	GO:0022008	neurogenesis

0.69	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0097472	cyclin-dependent protein kinase activity
0.34	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.33	GO:0003676	nucleic acid binding
0.33	GO:0005515	protein binding
0.33	GO:0004386	helicase activity

0.48	GO:0036064	ciliary basal body
0.44	GO:0016592	mediator complex
0.33	GO:0005737	cytoplasm

0.69