Queries 16001 to 17000

GO:0016681

sp|P00157|CYB_BOVIN
Cytochrome b
Search

CYTB

0.44	Cytochrome b

0.72

GO:0006122

mitochondrial electron transport, ubiquinol to cytochrome c

0.72	GO:0016681	oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor
0.62	GO:0009055	electron transfer activity
0.53	GO:0046872	metal ion binding
0.35	GO:0048039	ubiquinone binding
0.33	GO:0020037	heme binding

0.71	GO:0045275	respiratory chain complex III
0.61	GO:0031966	mitochondrial membrane
0.61	GO:0019866	organelle inner membrane
0.35	GO:0031301	integral component of organelle membrane
0.34	GO:0098798	mitochondrial protein complex

0.72

GO:0016681

sp|P00171|CYB5_BOVIN
Cytochrome b5
Search

CYB5A

0.64	Microsomal cytochrome b5 type A

0.42	GO:0071466	cellular response to xenobiotic stimulus
0.39	GO:0046686	response to cadmium ion
0.36	GO:0055114	oxidation-reduction process
0.35	GO:0019852	L-ascorbic acid metabolic process
0.34	GO:0006091	generation of precursor metabolites and energy
0.33	GO:0006631	fatty acid metabolic process
0.33	GO:1902600	hydrogen ion transmembrane transport

0.60	GO:0020037	heme binding
0.52	GO:0046872	metal ion binding
0.48	GO:0019899	enzyme binding
0.35	GO:0004033	aldo-keto reductase (NADP) activity
0.35	GO:0004768	stearoyl-CoA 9-desaturase activity
0.34	GO:0009055	electron transfer activity
0.33	GO:0015002	heme-copper terminal oxidase activity
0.33	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.33	GO:0015078	hydrogen ion transmembrane transporter activity

0.47	GO:0005829	cytosol
0.43	GO:0005739	mitochondrion
0.41	GO:0005789	endoplasmic reticulum membrane
0.38	GO:0031090	organelle membrane
0.36	GO:0070062	extracellular exosome
0.34	GO:0098805	whole membrane
0.33	GO:0019867	outer membrane
0.33	GO:0031967	organelle envelope
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:1.1.1

GO:0004033

sp|P00189|CP11A_BOVIN
Cholesterol side-chain cleavage enzyme, mitochondrial
Search

CYP11A1

0.94	Cholesterol side-chain cleavage enzyme, mitochondrial

0.84	GO:0006700	C21-steroid hormone biosynthetic process
0.77	GO:0008203	cholesterol metabolic process
0.53	GO:0055114	oxidation-reduction process
0.42	GO:0034650	cortisol metabolic process
0.39	GO:0042359	vitamin D metabolic process
0.37	GO:0033595	response to genistein
0.37	GO:0018879	biphenyl metabolic process
0.37	GO:0018963	phthalate metabolic process
0.37	GO:0032341	aldosterone metabolic process
0.37	GO:0018894	dibenzo-p-dioxin metabolic process

0.84	GO:0008386	cholesterol monooxygenase (side-chain-cleaving) activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.37	GO:0047783	corticosterone 18-monooxygenase activity
0.37	GO:0004507	steroid 11-beta-monooxygenase activity
0.35	GO:0015485	cholesterol binding
0.34	GO:0005515	protein binding
0.33	GO:0004743	pyruvate kinase activity
0.33	GO:0030955	potassium ion binding
0.32	GO:0000287	magnesium ion binding

0.58	GO:0031966	mitochondrial membrane
0.41	GO:0019866	organelle inner membrane
0.36	GO:0043204	perikaryon
0.35	GO:0005759	mitochondrial matrix
0.30	GO:0031224	intrinsic component of membrane

0.84

EC:1.14.15.6

GO:0008386

sp|P00191|CP21A_BOVIN
Steroid 21-hydroxylase
Search

CYP21A2

0.97	Mutant 21-hydroxylase B

0.53	GO:0055114	oxidation-reduction process
0.43	GO:0006694	steroid biosynthetic process
0.38	GO:0008212	mineralocorticoid metabolic process
0.36	GO:0042446	hormone biosynthetic process
0.36	GO:0008211	glucocorticoid metabolic process
0.36	GO:0042448	progesterone metabolic process
0.35	GO:0006956	complement activation
0.35	GO:0071375	cellular response to peptide hormone stimulus
0.35	GO:0016125	sterol metabolic process
0.35	GO:0006954	inflammatory response

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.66	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.45	GO:0005496	steroid binding
0.34	GO:0004866	endopeptidase inhibitor activity
0.32	GO:0016829	lyase activity

0.42	GO:0005789	endoplasmic reticulum membrane
0.39	GO:0031090	organelle membrane
0.34	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane

0.68

EC:1.14

GO:0016705

sp|P00257|ADX_BOVIN
Adrenodoxin, mitochondrial
Search

FDX1

0.61	Adrenodoxin, mitochondrial

0.61	GO:0022900	electron transport chain
0.55	GO:1904321	response to forskolin
0.54	GO:0071320	cellular response to cAMP
0.53	GO:1901655	cellular response to ketone
0.53	GO:0008203	cholesterol metabolic process
0.51	GO:0035690	cellular response to drug
0.51	GO:0042446	hormone biosynthetic process
0.50	GO:0071396	cellular response to lipid
0.44	GO:1904087	negative regulation of epiboly involved in gastrulation with mouth forming second
0.41	GO:0006694	steroid biosynthetic process

0.71	GO:0051537	2 iron, 2 sulfur cluster binding
0.62	GO:0009055	electron transfer activity
0.35	GO:0046872	metal ion binding
0.35	GO:0008022	protein C-terminus binding
0.35	GO:0008386	cholesterol monooxygenase (side-chain-cleaving) activity
0.35	GO:0015039	NADPH-adrenodoxin reductase activity
0.35	GO:0042803	protein homodimerization activity
0.34	GO:0019899	enzyme binding

0.44	GO:0005739	mitochondrion
0.38	GO:0031974	membrane-enclosed lumen
0.36	GO:0044446	intracellular organelle part
0.33	GO:0031090	organelle membrane
0.33	GO:0031975	envelope
0.30	GO:0044425	membrane part

0.35

EC:1.14.15.6

GO:0008386

sp|P00366|DHE3_BOVIN
Glutamate dehydrogenase 1, mitochondrial
Search

GLUD1

0.45	Glutamate dehydrogenase

0.57	GO:0006520	cellular amino acid metabolic process
0.50	GO:0055114	oxidation-reduction process
0.47	GO:0032024	positive regulation of insulin secretion
0.43	GO:0072350	tricarboxylic acid metabolic process
0.42	GO:0043649	dicarboxylic acid catabolic process
0.40	GO:0032094	response to food
0.39	GO:0043650	dicarboxylic acid biosynthetic process
0.39	GO:1901565	organonitrogen compound catabolic process
0.38	GO:0021762	substantia nigra development
0.38	GO:0010044	response to aluminum ion

0.71	GO:0016639	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
0.44	GO:0070728	leucine binding
0.40	GO:0043531	ADP binding
0.39	GO:0032550	purine ribonucleoside binding
0.39	GO:0019001	guanyl nucleotide binding
0.38	GO:0070403	NAD+ binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0005515	protein binding
0.35	GO:0008144	drug binding

0.46	GO:0005759	mitochondrial matrix
0.40	GO:0031966	mitochondrial membrane
0.40	GO:0019866	organelle inner membrane

0.71

EC:1.4.1

GO:0016639

sp|P00376|DYR_BOVIN
Dihydrofolate reductase
Search

DHFR

0.42	Viral dihydrofolate reductase

0.75	GO:0046654	tetrahydrofolate biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.49	GO:0051000	positive regulation of nitric-oxide synthase activity
0.49	GO:2000121	regulation of removal of superoxide radicals
0.48	GO:0046146	tetrahydrobiopterin metabolic process
0.48	GO:0034312	diol biosynthetic process
0.45	GO:0031427	response to methotrexate
0.44	GO:0003232	bulbus arteriosus development
0.43	GO:0046452	dihydrofolate metabolic process
0.43	GO:0046655	folic acid metabolic process

0.79	GO:0004146	dihydrofolate reductase activity
0.44	GO:0051870	methotrexate binding
0.44	GO:0003729	mRNA binding
0.43	GO:0000900	translation repressor activity, nucleic acid binding
0.42	GO:0005542	folic acid binding
0.41	GO:0070402	NADPH binding
0.40	GO:0051871	dihydrofolic acid binding
0.36	GO:0033560	folate reductase activity
0.33	GO:0004386	helicase activity
0.33	GO:0016757	transferase activity, transferring glycosyl groups

0.43	GO:0005739	mitochondrion
0.35	GO:0005829	cytosol
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0019866	organelle inner membrane
0.34	GO:0000439	core TFIIH complex
0.30	GO:0016021	integral component of membrane

0.79	EC:1.5.1.3	GO:0004146
0.33	KEGG:R02101	GO:0004799

sp|P00396|COX1_BOVIN
Cytochrome c oxidase subunit 1
Search

COX1

0.43	Cytochrome c oxidase subunit 1

0.64	GO:0006119	oxidative phosphorylation
0.64	GO:0009060	aerobic respiration
0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0022900	electron transport chain

0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0020037	heme binding
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.63	GO:0005506	iron ion binding
0.62	GO:0009055	electron transfer activity

0.75	GO:0045277	respiratory chain complex IV
0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.35	GO:0098798	mitochondrial protein complex
0.34	GO:0045275	respiratory chain complex III
0.30	GO:0016021	integral component of membrane

0.65

GO:0016676

sp|P00415|COX3_BOVIN
Cytochrome c oxidase subunit 3
Search

COX3

0.45	Cytochrome c oxidase subunit 3

0.76	GO:0019646	aerobic electron transport chain
0.63	GO:1902600	hydrogen ion transmembrane transport
0.44	GO:0008535	respiratory chain complex IV assembly

0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity

0.61	GO:0005739	mitochondrion
0.42	GO:0045277	respiratory chain complex IV
0.38	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.65

GO:0016676

sp|P00423|COX41_BOVIN
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial
Search

COX4I1

0.56	Mitochondrial cytochrome c oxidase subunit IV

0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0022900	electron transport chain
0.42	GO:0001666	response to hypoxia
0.41	GO:0006119	oxidative phosphorylation
0.41	GO:0009060	aerobic respiration
0.38	GO:0007584	response to nutrient
0.34	GO:0006470	protein dephosphorylation
0.34	GO:0050829	defense response to Gram-negative bacterium
0.34	GO:0007017	microtubule-based process
0.34	GO:0007010	cytoskeleton organization

0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity
0.35	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.34	GO:0005200	structural constituent of cytoskeleton
0.34	GO:0001530	lipopolysaccharide binding
0.34	GO:0005515	protein binding
0.33	GO:0004725	protein tyrosine phosphatase activity
0.33	GO:0003924	GTPase activity

0.55	GO:0005751	mitochondrial respiratory chain complex IV
0.44	GO:0005634	nucleus
0.36	GO:0070062	extracellular exosome
0.34	GO:0005874	microtubule
0.30	GO:0031224	intrinsic component of membrane

0.65

GO:0016676

sp|P00426|COX5A_BOVIN
Cytochrome c oxidase subunit 5A, mitochondrial
Search

COX5A

0.88	Cytochrome c oxidase polypeptide Va

0.62	GO:1902600	hydrogen ion transmembrane transport
0.60	GO:0022900	electron transport chain
0.41	GO:0006119	oxidative phosphorylation
0.41	GO:0009060	aerobic respiration
0.37	GO:0021522	spinal cord motor neuron differentiation
0.36	GO:0048568	embryonic organ development

0.64	GO:0015002	heme-copper terminal oxidase activity
0.64	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.62	GO:0015078	hydrogen ion transmembrane transporter activity
0.61	GO:0009055	electron transfer activity
0.40	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding
0.32	GO:0003676	nucleic acid binding

0.61	GO:0031966	mitochondrial membrane
0.61	GO:0019866	organelle inner membrane
0.52	GO:0043209	myelin sheath
0.51	GO:0045277	respiratory chain complex IV
0.51	GO:0098798	mitochondrial protein complex
0.37	GO:0070062	extracellular exosome

0.64

GO:0016676

sp|P00428|COX5B_BOVIN
Cytochrome c oxidase subunit 5B, mitochondrial
Search

COX5B

0.85	Cytochrome c oxidase polypeptide Vb

0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0022900	electron transport chain
0.47	GO:0006839	mitochondrial transport
0.45	GO:0006754	ATP biosynthetic process
0.44	GO:0046907	intracellular transport
0.43	GO:0006119	oxidative phosphorylation
0.43	GO:0009060	aerobic respiration
0.35	GO:0007585	respiratory gaseous exchange
0.35	GO:0043434	response to peptide hormone
0.34	GO:0033617	mitochondrial respiratory chain complex IV assembly

0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity
0.36	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding
0.32	GO:0003700	DNA binding transcription factor activity
0.31	GO:0003677	DNA binding

0.62	GO:0044429	mitochondrial part
0.62	GO:0031967	organelle envelope
0.47	GO:0045277	respiratory chain complex IV
0.42	GO:0031090	organelle membrane
0.36	GO:0043209	myelin sheath
0.36	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.65

GO:0016676

sp|P00429|CX6B1_BOVIN
Cytochrome c oxidase subunit 6B1
Search

COX6B1

0.74	Cytochrome c oxidase subunit

0.38	GO:0021762	substantia nigra development
0.35	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen
0.34	GO:0034968	histone lysine methylation
0.34	GO:1902600	hydrogen ion transmembrane transport
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.34	GO:0043565	sequence-specific DNA binding
0.34	GO:0018024	histone-lysine N-methyltransferase activity
0.34	GO:0015002	heme-copper terminal oxidase activity
0.34	GO:0016675	oxidoreductase activity, acting on a heme group of donors
0.34	GO:0003700	DNA binding transcription factor activity
0.34	GO:0015078	hydrogen ion transmembrane transporter activity
0.34	GO:0009055	electron transfer activity
0.33	GO:0008270	zinc ion binding

0.61	GO:0005739	mitochondrion
0.43	GO:0031967	organelle envelope
0.42	GO:0031090	organelle membrane
0.37	GO:0031974	membrane-enclosed lumen
0.34	GO:0005634	nucleus
0.34	GO:0045277	respiratory chain complex IV
0.30	GO:0016021	integral component of membrane

0.34

EC:2.1.1.43

GO:0018024

sp|P00430|COX7C_BOVIN
Cytochrome c oxidase subunit 7C, mitochondrial
Search

COX7C

0.94	Cytochrome c oxidase polypeptide VIIc

0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0022900	electron transport chain
0.45	GO:0006119	oxidative phosphorylation
0.45	GO:0009060	aerobic respiration

0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity

0.54	GO:0005751	mitochondrial respiratory chain complex IV
0.30	GO:0031224	intrinsic component of membrane

0.65

GO:0016676

sp|P00432|CATA_BOVIN
Catalase
Search

CAT

0.54

Catalase

0.76	GO:0042744	hydrogen peroxide catabolic process
0.71	GO:0006979	response to oxidative stress
0.69	GO:0098869	cellular oxidant detoxification
0.55	GO:0009650	UV protection
0.55	GO:0020027	hemoglobin metabolic process
0.53	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling
0.53	GO:0051289	protein homotetramerization
0.53	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.52	GO:0055114	oxidation-reduction process
0.52	GO:0051092	positive regulation of NF-kappaB transcription factor activity

0.77	GO:0004096	catalase activity
0.63	GO:0020037	heme binding
0.53	GO:0004046	aminoacylase activity
0.53	GO:0046872	metal ion binding
0.49	GO:0042803	protein homodimerization activity
0.48	GO:0005102	receptor binding
0.47	GO:0019899	enzyme binding
0.47	GO:0050661	NADP binding
0.35	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity

0.53	GO:0005777	peroxisome
0.51	GO:0031903	microbody membrane
0.44	GO:0005739	mitochondrion
0.37	GO:0031970	organelle envelope lumen
0.37	GO:0005764	lysosome
0.36	GO:0005615	extracellular space
0.36	GO:0005925	focal adhesion
0.36	GO:1903561	extracellular vesicle
0.36	GO:0005794	Golgi apparatus
0.36	GO:0005783	endoplasmic reticulum

0.77

EC:1.11.1.6

GO:0004096

sp|P00435|GPX1_BOVIN
Glutathione peroxidase 1
Search

GPX1

0.47	Glutathione peroxidase

0.71	GO:0006979	response to oxidative stress
0.69	GO:0098869	cellular oxidant detoxification
0.53	GO:0055114	oxidation-reduction process
0.53	GO:0009609	response to symbiotic bacterium
0.51	GO:0002862	negative regulation of inflammatory response to antigenic stimulus
0.51	GO:0051450	myoblast proliferation
0.51	GO:0010269	response to selenium ion
0.50	GO:0001659	temperature homeostasis
0.50	GO:1902176	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
0.50	GO:0043403	skeletal muscle tissue regeneration

0.79	GO:0004602	glutathione peroxidase activity
0.46	GO:0017124	SH3 domain binding
0.36	GO:0003924	GTPase activity
0.36	GO:0005525	GTP binding
0.33	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.33	GO:0031685	adenosine receptor binding
0.33	GO:0009055	electron transfer activity
0.32	GO:0042802	identical protein binding

0.50	GO:0097413	Lewy body
0.44	GO:0005829	cytosol
0.41	GO:0005739	mitochondrion
0.39	GO:0005615	extracellular space
0.38	GO:1903561	extracellular vesicle
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0005634	nucleus
0.33	GO:0044446	intracellular organelle part
0.31	GO:0005886	plasma membrane

0.79

EC:1.11.1.9

GO:0004602

sp|P00442|SODC_BOVIN
Superoxide dismutase [Cu-Zn]
Search

SOD1

0.54	Superoxide dismutase [Cu-Zn]

0.75	GO:0006801	superoxide metabolic process
0.75	GO:0071450	cellular response to oxygen radical
0.75	GO:0000303	response to superoxide
0.69	GO:0098869	cellular oxidant detoxification
0.58	GO:0045541	negative regulation of cholesterol biosynthetic process
0.57	GO:0060087	relaxation of vascular smooth muscle
0.57	GO:0050665	hydrogen peroxide biosynthetic process
0.56	GO:0060088	auditory receptor cell stereocilium organization
0.56	GO:0032287	peripheral nervous system myelin maintenance
0.56	GO:0060052	neurofilament cytoskeleton organization

0.77	GO:0004784	superoxide dismutase activity
0.58	GO:0030346	protein phosphatase 2B binding
0.54	GO:0046872	metal ion binding
0.52	GO:0048365	Rac GTPase binding
0.51	GO:0051087	chaperone binding
0.48	GO:0042802	identical protein binding
0.35	GO:0046983	protein dimerization activity
0.34	GO:0004842	ubiquitin-protein transferase activity

0.57	GO:0032839	dendrite cytoplasm
0.53	GO:0043025	neuronal cell body
0.51	GO:1904115	axon cytoplasm
0.51	GO:0005615	extracellular space
0.50	GO:0043209	myelin sheath
0.50	GO:0031012	extracellular matrix
0.49	GO:0031410	cytoplasmic vesicle
0.49	GO:0005777	peroxisome
0.48	GO:0005829	cytosol
0.46	GO:0005634	nucleus

0.77	EC:1.15.1.1	GO:0004784
0.34	KEGG:R03876	GO:0004842

sp|P00514|KAP0_BOVIN
cAMP-dependent protein kinase type I-alpha regulatory subunit
Search

PRKAR1A

0.97	cAMP-dependent protein kinase type I-alpha regulatory subunit

0.75	GO:0045859	regulation of protein kinase activity
0.57	GO:0046007	negative regulation of activated T cell proliferation
0.56	GO:0060038	cardiac muscle cell proliferation
0.54	GO:0033673	negative regulation of kinase activity
0.54	GO:0045214	sarcomere organization
0.54	GO:0001707	mesoderm formation
0.51	GO:0001933	negative regulation of protein phosphorylation
0.51	GO:0016310	phosphorylation
0.40	GO:0051445	regulation of meiotic cell cycle
0.39	GO:0007143	female meiotic nuclear division

0.84	GO:0008603	cAMP-dependent protein kinase regulator activity
0.83	GO:0030552	cAMP binding
0.58	GO:0034236	protein kinase A catalytic subunit binding
0.57	GO:0004862	cAMP-dependent protein kinase inhibitor activity
0.53	GO:0016301	kinase activity
0.52	GO:0031625	ubiquitin protein ligase binding
0.51	GO:0019904	protein domain specific binding
0.34	GO:0042802	identical protein binding
0.33	GO:0004888	transmembrane signaling receptor activity
0.32	GO:0016773	phosphotransferase activity, alcohol group as acceptor

0.83	GO:0005952	cAMP-dependent protein kinase complex
0.56	GO:0001772	immunological synapse
0.55	GO:0031588	nucleotide-activated protein kinase complex
0.54	GO:0044853	plasma membrane raft
0.54	GO:0031594	neuromuscular junction
0.53	GO:0005930	axoneme
0.35	GO:0097546	ciliary base
0.33	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.32

GO:0016773

sp|P00515|KAP2_BOVIN
cAMP-dependent protein kinase type II-alpha regulatory subunit
Search

PRKAR2A

0.96	cAMP-dependent protein kinase type II-alpha regulatory subunit

0.74	GO:0045859	regulation of protein kinase activity
0.57	GO:0033673	negative regulation of kinase activity
0.54	GO:0001933	negative regulation of protein phosphorylation
0.50	GO:0016310	phosphorylation
0.47	GO:0007612	learning
0.42	GO:0006631	fatty acid metabolic process
0.39	GO:0097338	response to clozapine
0.37	GO:1904146	positive regulation of meiotic cell cycle process involved in oocyte maturation
0.35	GO:0071377	cellular response to glucagon stimulus
0.35	GO:0003091	renal water homeostasis

0.84	GO:0008603	cAMP-dependent protein kinase regulator activity
0.83	GO:0030552	cAMP binding
0.61	GO:0034236	protein kinase A catalytic subunit binding
0.61	GO:0004862	cAMP-dependent protein kinase inhibitor activity
0.56	GO:0031625	ubiquitin protein ligase binding
0.52	GO:0016301	kinase activity
0.51	GO:0019904	protein domain specific binding
0.36	GO:0031698	beta-2 adrenergic receptor binding
0.35	GO:0005476	carnitine:acyl carnitine antiporter activity
0.35	GO:0015226	carnitine transmembrane transporter activity

0.83	GO:0005952	cAMP-dependent protein kinase complex
0.56	GO:0044441	ciliary part
0.56	GO:0005813	centrosome
0.54	GO:0031588	nucleotide-activated protein kinase complex
0.54	GO:0044853	plasma membrane raft
0.52	GO:0032838	plasma membrane bounded cell projection cytoplasm
0.48	GO:0043198	dendritic shaft
0.47	GO:0043197	dendritic spine
0.37	GO:0070062	extracellular exosome
0.37	GO:0048471	perinuclear region of cytoplasm

sp|P00516|KGP1_BOVIN
cGMP-dependent protein kinase 1
Search

0.84	cGMP-dependent protein kinase

0.63	GO:0006468	protein phosphorylation
0.55	GO:0090331	negative regulation of platelet aggregation
0.54	GO:1904753	negative regulation of vascular associated smooth muscle cell migration
0.53	GO:1904706	negative regulation of vascular smooth muscle cell proliferation
0.51	GO:0060087	relaxation of vascular smooth muscle
0.51	GO:0019934	cGMP-mediated signaling
0.49	GO:0001764	neuron migration
0.49	GO:0016358	dendrite development
0.48	GO:0043087	regulation of GTPase activity
0.48	GO:0030900	forebrain development

0.85	GO:0004692	cGMP-dependent protein kinase activity
0.73	GO:0030553	cGMP binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.53	GO:0005246	calcium channel regulator activity
0.38	GO:0042802	identical protein binding
0.38	GO:0008603	cAMP-dependent protein kinase regulator activity
0.36	GO:0048273	mitogen-activated protein kinase p38 binding
0.34	GO:0046983	protein dimerization activity

0.44	GO:0005794	Golgi apparatus
0.40	GO:0005886	plasma membrane
0.38	GO:0005952	cAMP-dependent protein kinase complex
0.36	GO:0005829	cytosol
0.35	GO:0001669	acrosomal vesicle
0.34	GO:0005654	nucleoplasm
0.32	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.85

EC:2.7.11.12

GO:0004692

sp|P00517|KAPCA_BOVIN
cAMP-dependent protein kinase catalytic subunit alpha
Search

PRKACA

0.83	cAMP-dependent protein kinase catalytic subunit alpha

0.62	GO:0006468	protein phosphorylation
0.59	GO:1901621	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
0.56	GO:0001843	neural tube closure
0.56	GO:0070613	regulation of protein processing
0.51	GO:2000810	regulation of bicellular tight junction assembly
0.51	GO:0071374	cellular response to parathyroid hormone stimulus
0.50	GO:0048240	sperm capacitation
0.50	GO:0034605	cellular response to heat
0.50	GO:0071333	cellular response to glucose stimulus
0.49	GO:0071158	positive regulation of cell cycle arrest

0.69	GO:0004674	protein serine/threonine kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.54	GO:0031625	ubiquitin protein ligase binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0008144	drug binding
0.52	GO:0034237	protein kinase A regulatory subunit binding
0.49	GO:0060089	molecular transducer activity
0.48	GO:0004712	protein serine/threonine/tyrosine kinase activity
0.47	GO:0000287	magnesium ion binding

0.58	GO:0097546	ciliary base
0.57	GO:0045171	intercellular bridge
0.53	GO:0005813	centrosome
0.51	GO:0005952	cAMP-dependent protein kinase complex
0.50	GO:0036126	sperm flagellum
0.50	GO:0001669	acrosomal vesicle
0.50	GO:0048471	perinuclear region of cytoplasm
0.49	GO:0005829	cytosol
0.49	GO:0044853	plasma membrane raft
0.48	GO:0043197	dendritic spine

0.69

GO:0004674

sp|P00570|KAD1_BOVIN
Adenylate kinase isoenzyme 1
Search

AK1

0.91	Adenylate kinase isoenzyme 1

0.77	GO:0006172	ADP biosynthetic process
0.67	GO:0046033	AMP metabolic process
0.66	GO:0046939	nucleotide phosphorylation
0.64	GO:0009142	nucleoside triphosphate biosynthetic process
0.59	GO:0046034	ATP metabolic process
0.52	GO:0007050	cell cycle arrest
0.37	GO:0097503	sialylation
0.37	GO:0033993	response to lipid
0.36	GO:0006486	protein glycosylation
0.36	GO:1901700	response to oxygen-containing compound

0.74	GO:0004017	adenylate kinase activity
0.73	GO:0004550	nucleoside diphosphate kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0008373	sialyltransferase activity
0.35	GO:0030695	GTPase regulator activity
0.34	GO:0019206	nucleoside kinase activity

0.54	GO:0001520	outer dense fiber
0.47	GO:0005737	cytoplasm
0.41	GO:0005886	plasma membrane
0.36	GO:0070062	extracellular exosome
0.35	GO:0005815	microtubule organizing center
0.34	GO:0043005	neuron projection
0.30	GO:0016021	integral component of membrane

0.74

EC:2.7.4.3

GO:0004017

sp|P00586|THTR_BOVIN
Thiosulfate sulfurtransferase
Search

TST

0.50	Thiosulfate sulfurtransferase

0.62	GO:0035928	rRNA import into mitochondrion
0.54	GO:0030855	epithelial cell differentiation
0.36	GO:0009440	cyanate catabolic process
0.34	GO:0016226	iron-sulfur cluster assembly

0.78	GO:0004792	thiosulfate sulfurtransferase activity
0.54	GO:0008097	5S rRNA binding
0.33	GO:0005515	protein binding

0.46	GO:0044429	mitochondrial part
0.46	GO:0019866	organelle inner membrane
0.38	GO:0031974	membrane-enclosed lumen
0.36	GO:0070062	extracellular exosome

0.78	EC:2.8.1.1	GO:0004792
0.78	KEGG:R01931	GO:0004792

sp|P00593|PA21B_BOVIN
Phospholipase A2
Search

PLA2G1B

0.67	Phospholipase A2, major isoenzyme

0.82	GO:0050482	arachidonic acid secretion
0.72	GO:0016042	lipid catabolic process
0.67	GO:0006644	phospholipid metabolic process
0.55	GO:0002227	innate immune response in mucosa
0.55	GO:0044241	lipid digestion
0.54	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.53	GO:0044243	multicellular organismal catabolic process
0.53	GO:0019731	antibacterial humoral response
0.53	GO:0045740	positive regulation of DNA replication
0.52	GO:0050830	defense response to Gram-positive bacterium

0.82	GO:0004623	phospholipase A2 activity
0.79	GO:0102568	phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
0.79	GO:0102567	phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
0.70	GO:0005509	calcium ion binding
0.48	GO:0005102	receptor binding
0.41	GO:0090729	toxin activity
0.37	GO:0032052	bile acid binding
0.33	GO:0003723	RNA binding
0.32	GO:0016301	kinase activity

0.65	GO:0005576	extracellular region
0.49	GO:0009986	cell surface
0.46	GO:0005829	cytosol
0.37	GO:0030141	secretory granule
0.36	GO:0072556	other organism presynaptic membrane
0.30	GO:0016020	membrane

0.82

EC:3.1.1.4

GO:0004623

sp|P00639|DNAS1_BOVIN
Deoxyribonuclease-1
Search

DNASE1

0.63	Deoxyribonuclease

0.76	GO:0006308	DNA catabolic process
0.61	GO:0070948	regulation of neutrophil mediated cytotoxicity
0.59	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.59	GO:0002283	neutrophil activation involved in immune response
0.58	GO:0002673	regulation of acute inflammatory response
0.49	GO:0003335	corneocyte development
0.46	GO:0001942	hair follicle development
0.44	GO:0006915	apoptotic process
0.36	GO:0010623	programmed cell death involved in cell development
0.35	GO:0022411	cellular component disassembly

0.71	GO:0004536	deoxyribonuclease activity
0.61	GO:0004519	endonuclease activity
0.42	GO:0003779	actin binding
0.33	GO:0005509	calcium ion binding
0.32	GO:0003677	DNA binding

0.43	GO:0005634	nucleus
0.41	GO:0012505	endomembrane system
0.41	GO:0005576	extracellular region
0.39	GO:0031967	organelle envelope
0.35	GO:0031982	vesicle
0.33	GO:0044444	cytoplasmic part
0.30	GO:0031224	intrinsic component of membrane

sp|P00669|RNS_BOVIN
Seminal ribonuclease
Search

RNASE1

0.55	Seminal ribonuclease

0.62	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.49	GO:0051607	defense response to virus
0.46	GO:0016070	RNA metabolic process

0.71	GO:0004522	ribonuclease A activity
0.51	GO:0003676	nucleic acid binding
0.48	GO:0042802	identical protein binding

0.54

GO:0005576

extracellular region

0.71

EC:3.1.27.5

GO:0004522

sp|P00711|LALBA_BOVIN
Alpha-lactalbumin
Search

LALBA

0.91	Alpha-lactalbumin protein variant D

0.86	GO:0005989	lactose biosynthetic process
0.46	GO:1903496	response to 11-deoxycorticosterone
0.46	GO:1903494	response to dehydroepiandrosterone
0.44	GO:0032570	response to progesterone
0.44	GO:0032355	response to estradiol
0.44	GO:0050830	defense response to Gram-positive bacterium
0.43	GO:0050829	defense response to Gram-negative bacterium
0.42	GO:0016998	cell wall macromolecule catabolic process
0.34	GO:0006915	apoptotic process
0.34	GO:0007267	cell-cell signaling

0.86	GO:0004461	lactose synthase activity
0.70	GO:0005509	calcium ion binding
0.42	GO:0003796	lysozyme activity
0.35	GO:0042802	identical protein binding

0.44	GO:0005576	extracellular region
0.35	GO:0005796	Golgi lumen
0.34	GO:0000139	Golgi membrane

0.86

EC:2.4.1.22

GO:0004461

sp|P00727|AMPL_BOVIN
Cytosol aminopeptidase
Search

LAP3

0.70	Cytosol aminopeptidase

0.61

GO:0006508

proteolysis

0.74	GO:0008235	metalloexopeptidase activity
0.73	GO:0030145	manganese ion binding
0.71	GO:0004177	aminopeptidase activity
0.35	GO:0097718	disordered domain specific binding

0.55	GO:0030496	midbody
0.49	GO:0005654	nucleoplasm
0.49	GO:0005737	cytoplasm
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.36	GO:0031984	organelle subcompartment
0.36	GO:0012505	endomembrane system

0.71

EC:3.4.11

GO:0004177

sp|P00730|CBPA1_BOVIN
Carboxypeptidase A1
Search

CPA1

0.83	Preprocarboxypeptidase A

0.61	GO:0006508	proteolysis
0.35	GO:0044257	cellular protein catabolic process

0.78	GO:0004181	metallocarboxypeptidase activity
0.63	GO:0008270	zinc ion binding
0.33	GO:0005515	protein binding

0.50	GO:0005615	extracellular space
0.34	GO:0005773	vacuole
0.30	GO:0016020	membrane

0.78

GO:0004181

sp|P00732|CBPB1_BOVIN
Carboxypeptidase B
Search

CPB1

0.79	Pancreatic carboxypeptidase B

0.60	GO:0006508	proteolysis
0.36	GO:0002002	regulation of angiotensin levels in blood
0.36	GO:0042730	fibrinolysis
0.34	GO:0071466	cellular response to xenobiotic stimulus

0.76	GO:0004181	metallocarboxypeptidase activity
0.62	GO:0008270	zinc ion binding

0.45	GO:0005615	extracellular space
0.42	GO:0046658	anchored component of plasma membrane
0.35	GO:0031012	extracellular matrix
0.35	GO:0016324	apical plasma membrane
0.30	GO:0016021	integral component of membrane

0.76

GO:0004181

sp|P00735|THRB_BOVIN
Prothrombin
Search

0.97	Prothrombin

0.78	GO:0007596	blood coagulation
0.77	GO:0006953	acute-phase response
0.61	GO:0051838	cytolysis by host of symbiont cells
0.60	GO:0070945	neutrophil mediated killing of gram-negative bacterium
0.60	GO:1900738	positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway
0.58	GO:1900016	negative regulation of cytokine production involved in inflammatory response
0.58	GO:0048712	negative regulation of astrocyte differentiation
0.58	GO:0006508	proteolysis
0.58	GO:0042730	fibrinolysis
0.58	GO:0032967	positive regulation of collagen biosynthetic process

0.67	GO:0005509	calcium ion binding
0.66	GO:0004252	serine-type endopeptidase activity
0.60	GO:0070053	thrombospondin receptor activity
0.55	GO:0008201	heparin binding
0.55	GO:0001530	lipopolysaccharide binding
0.50	GO:0005102	receptor binding
0.35	GO:0030545	receptor regulator activity
0.30	GO:0070051	fibrinogen binding

0.63	GO:0005576	extracellular region
0.54	GO:0009897	external side of plasma membrane
0.36	GO:0005796	Golgi lumen
0.36	GO:0031982	vesicle
0.36	GO:0005788	endoplasmic reticulum lumen

0.66

GO:0004252

sp|P00741|FA9_BOVIN
Coagulation factor IX
Search

0.85	Coagulation factor IXb

0.81	GO:0007596	blood coagulation
0.63	GO:0031638	zymogen activation
0.47	GO:0051897	positive regulation of protein kinase B signaling
0.37	GO:0017187	peptidyl-glutamic acid carboxylation
0.37	GO:0072376	protein activation cascade
0.36	GO:0006465	signal peptide processing
0.36	GO:0006888	ER to Golgi vesicle-mediated transport
0.34	GO:0030335	positive regulation of cell migration

0.68	GO:0004252	serine-type endopeptidase activity
0.67	GO:0005509	calcium ion binding
0.44	GO:0005543	phospholipid binding
0.34	GO:0005515	protein binding
0.34	GO:0000287	magnesium ion binding

0.64	GO:0005576	extracellular region
0.37	GO:0005796	Golgi lumen
0.37	GO:0005788	endoplasmic reticulum lumen
0.36	GO:0031982	vesicle
0.34	GO:0031233	intrinsic component of external side of plasma membrane
0.30	GO:0016021	integral component of membrane

0.68

GO:0004252

sp|P00743|FA10_BOVIN
Coagulation factor X
Search

F10

0.85	Coagulation factor IX

0.76	GO:0007596	blood coagulation
0.61	GO:0006508	proteolysis
0.59	GO:0051897	positive regulation of protein kinase B signaling
0.42	GO:0035807	positive regulation of blood coagulation in other organism
0.42	GO:0044469	envenomation resulting in positive regulation of blood coagulation in other organism
0.39	GO:0010952	positive regulation of peptidase activity
0.37	GO:0009405	pathogenesis
0.35	GO:0017187	peptidyl-glutamic acid carboxylation
0.35	GO:0072376	protein activation cascade
0.35	GO:0030335	positive regulation of cell migration

0.69	GO:0004252	serine-type endopeptidase activity
0.67	GO:0005509	calcium ion binding
0.54	GO:0005543	phospholipid binding
0.39	GO:0016504	peptidase activator activity
0.38	GO:0090729	toxin activity
0.35	GO:0005515	protein binding

0.64	GO:0005576	extracellular region
0.36	GO:0005796	Golgi lumen
0.36	GO:0031233	intrinsic component of external side of plasma membrane
0.36	GO:0005783	endoplasmic reticulum
0.34	GO:0005765	lysosomal membrane
0.30	GO:0016021	integral component of membrane

0.69

GO:0004252

sp|P00744|PROZ_BOVIN
Vitamin K-dependent protein Z
Search

PROZ

0.97	Vitamin K-dependent protein Z

0.74	GO:0007596	blood coagulation
0.58	GO:0006508	proteolysis
0.51	GO:0030193	regulation of blood coagulation
0.51	GO:1900047	negative regulation of hemostasis
0.51	GO:0050819	negative regulation of coagulation
0.51	GO:0061045	negative regulation of wound healing
0.43	GO:0051897	positive regulation of protein kinase B signaling
0.41	GO:0007219	Notch signaling pathway
0.39	GO:0030154	cell differentiation
0.38	GO:0007275	multicellular organism development

0.70	GO:0005509	calcium ion binding
0.66	GO:0004252	serine-type endopeptidase activity
0.41	GO:0005543	phospholipid binding
0.37	GO:0004872	receptor activity
0.36	GO:0016504	peptidase activator activity
0.36	GO:0090729	toxin activity
0.34	GO:0005515	protein binding
0.34	GO:0004623	phospholipase A2 activity
0.32	GO:0004725	protein tyrosine phosphatase activity
0.32	GO:0004672	protein kinase activity

0.64	GO:0005576	extracellular region
0.38	GO:0031982	vesicle
0.37	GO:0005796	Golgi lumen
0.37	GO:0005788	endoplasmic reticulum lumen
0.34	GO:0031233	intrinsic component of external side of plasma membrane
0.32	GO:0015935	small ribosomal subunit
0.30	GO:0016021	integral component of membrane

0.66

GO:0004252

sp|P00745|PROC_BOVIN
Vitamin K-dependent protein C (Fragment)
Search

PROC

0.92	Vitamin K-dependent protein C

0.77	GO:0007596	blood coagulation
0.62	GO:1903142	positive regulation of establishment of endothelial barrier
0.61	GO:0050819	negative regulation of coagulation
0.60	GO:0006508	proteolysis
0.60	GO:1900047	negative regulation of hemostasis
0.60	GO:0061045	negative regulation of wound healing
0.59	GO:0030193	regulation of blood coagulation
0.59	GO:0044537	regulation of circulating fibrinogen levels
0.58	GO:0050728	negative regulation of inflammatory response
0.54	GO:0001889	liver development

0.69	GO:0004252	serine-type endopeptidase activity
0.67	GO:0005509	calcium ion binding
0.37	GO:0070012	oligopeptidase activity
0.36	GO:0043621	protein self-association
0.34	GO:0004143	diacylglycerol kinase activity
0.34	GO:0003951	NAD+ kinase activity
0.34	GO:0005543	phospholipid binding
0.33	GO:0003677	DNA binding
0.33	GO:0005102	receptor binding
0.32	GO:0030554	adenyl nucleotide binding

0.64	GO:0005576	extracellular region
0.51	GO:0005794	Golgi apparatus
0.51	GO:0005783	endoplasmic reticulum
0.41	GO:1905286	serine-type peptidase complex
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0005634	nucleus
0.34	GO:0044446	intracellular organelle part
0.32	GO:0031982	vesicle
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.69	EC:3.4.21	GO:0004252
0.34	KEGG:R00104	GO:0003951

sp|P00760|TRY1_BOVIN
Cationic trypsin
Search

0.47	Cationic trypsinogen

0.61	GO:0006508	proteolysis
0.53	GO:0007586	digestion
0.38	GO:0007584	response to nutrient
0.38	GO:0031000	response to caffeine
0.38	GO:0030574	collagen catabolic process
0.38	GO:0035094	response to nicotine
0.36	GO:0043542	endothelial cell migration
0.35	GO:0022617	extracellular matrix disassembly
0.33	GO:0051604	protein maturation
0.33	GO:0009235	cobalamin metabolic process

0.69	GO:0004252	serine-type endopeptidase activity
0.38	GO:0005509	calcium ion binding
0.36	GO:0097655	serpin family protein binding
0.34	GO:0046982	protein heterodimerization activity

0.51	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.36	GO:0097180	serine protease inhibitor complex
0.30	GO:0016020	membrane

0.69

GO:0004252

sp|P00766|CTRA_BOVIN
Chymotrypsinogen A
Search

0.84	Chymotrypsinogen A

0.61	GO:0006508	proteolysis
0.43	GO:0007586	digestion
0.37	GO:0022617	extracellular matrix disassembly
0.35	GO:0009235	cobalamin metabolic process
0.35	GO:0032094	response to food
0.34	GO:0007584	response to nutrient
0.34	GO:0043434	response to peptide hormone
0.34	GO:0043065	positive regulation of apoptotic process
0.34	GO:0034097	response to cytokine
0.34	GO:0007596	blood coagulation

0.69	GO:0004252	serine-type endopeptidase activity
0.36	GO:0097655	serpin family protein binding
0.33	GO:0005509	calcium ion binding

0.40	GO:0005615	extracellular space
0.36	GO:0097180	serine protease inhibitor complex
0.34	GO:0005764	lysosome
0.34	GO:0000145	exocyst
0.30	GO:0016020	membrane

0.69

GO:0004252

sp|P00767|CTRB_BOVIN
Chymotrypsinogen B
Search

0.82	Chymotrypsinogen B

0.61	GO:0006508	proteolysis
0.42	GO:0007586	digestion
0.37	GO:0022617	extracellular matrix disassembly
0.35	GO:0032094	response to food
0.35	GO:0009235	cobalamin metabolic process
0.35	GO:0007584	response to nutrient
0.35	GO:0043434	response to peptide hormone
0.34	GO:0043065	positive regulation of apoptotic process
0.34	GO:0034097	response to cytokine
0.34	GO:0007596	blood coagulation

0.69	GO:0004252	serine-type endopeptidase activity
0.36	GO:0097655	serpin family protein binding
0.33	GO:0005509	calcium ion binding

0.40	GO:0005615	extracellular space
0.35	GO:0097180	serine protease inhibitor complex
0.34	GO:0005764	lysosome

0.69

GO:0004252

sp|P00792|PEPA_BOVIN
Pepsin A
Search

0.91	Pepsinogen III

0.61	GO:0006508	proteolysis
0.49	GO:0007586	digestion
0.49	GO:0006914	autophagy
0.46	GO:0030163	protein catabolic process
0.43	GO:0051604	protein maturation
0.39	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.34	GO:0044267	cellular protein metabolic process

0.70	GO:0070001	aspartic-type peptidase activity
0.65	GO:0004175	endopeptidase activity
0.36	GO:0042803	protein homodimerization activity

0.43	GO:0005576	extracellular region
0.40	GO:0097486	multivesicular body lumen
0.30	GO:0031224	intrinsic component of membrane

sp|P00794|CHYM_BOVIN
Chymosin
Search

0.92	Preprochymosin b

0.61	GO:0006508	proteolysis
0.48	GO:0007586	digestion
0.48	GO:0006914	autophagy
0.46	GO:0030163	protein catabolic process
0.39	GO:0051604	protein maturation
0.36	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.34	GO:0002803	positive regulation of antibacterial peptide production
0.34	GO:0003406	retinal pigment epithelium development
0.34	GO:0044265	cellular macromolecule catabolic process
0.34	GO:0044267	cellular protein metabolic process

0.70	GO:0070001	aspartic-type peptidase activity
0.65	GO:0004175	endopeptidase activity
0.35	GO:0042803	protein homodimerization activity

0.40	GO:0005576	extracellular region
0.37	GO:0097486	multivesicular body lumen
0.36	GO:0005764	lysosome
0.30	GO:0016020	membrane

sp|P00829|ATPB_BOVIN
ATP synthase subunit beta, mitochondrial
Search

ATP5B

0.43	Mitochondrial ATP synthase subunit beta

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.69	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.54	GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration
0.53	GO:0043536	positive regulation of blood vessel endothelial cell migration
0.51	GO:0051453	regulation of intracellular pH
0.51	GO:0001525	angiogenesis
0.42	GO:0006629	lipid metabolic process
0.36	GO:0001649	osteoblast differentiation
0.35	GO:0042407	cristae formation

0.71	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism
0.55	GO:0043532	angiostatin binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0042288	MHC class I protein binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0046961	proton-transporting ATPase activity, rotational mechanism
0.35	GO:0030228	lipoprotein particle receptor activity
0.34	GO:0005509	calcium ion binding
0.32	GO:0003677	DNA binding

0.71	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)
0.51	GO:0042645	mitochondrial nucleoid
0.50	GO:0043209	myelin sheath
0.49	GO:0005753	mitochondrial proton-transporting ATP synthase complex
0.48	GO:0009986	cell surface
0.40	GO:0005886	plasma membrane
0.36	GO:0031012	extracellular matrix
0.36	GO:0070062	extracellular exosome
0.35	GO:0005634	nucleus
0.34	GO:0045121	membrane raft

sp|P00847|ATP6_BOVIN
ATP synthase subunit a
Search

ATP6

0.42	ATP synthase subunit a

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.33	GO:0016887	ATPase activity

0.72	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)
0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.37	GO:0098798	mitochondrial protein complex
0.30	GO:0016021	integral component of membrane

0.33

GO:0016887

sp|P00921|CAH2_BOVIN
Carbonic anhydrase 2
Search

CA2

0.43	Red blood cell carbonic anhydrase II

0.71	GO:0006730	one-carbon metabolic process
0.57	GO:0015670	carbon dioxide transport
0.56	GO:0038166	angiotensin-activated signaling pathway
0.55	GO:2000878	positive regulation of oligopeptide transport
0.55	GO:2001148	regulation of dipeptide transmembrane transport
0.55	GO:0044070	regulation of anion transport
0.53	GO:0032849	positive regulation of cellular pH reduction
0.52	GO:0032230	positive regulation of synaptic transmission, GABAergic
0.50	GO:0034764	positive regulation of transmembrane transport
0.47	GO:0002009	morphogenesis of an epithelium

0.77	GO:0004089	carbonate dehydratase activity
0.63	GO:0008270	zinc ion binding
0.54	GO:0004064	arylesterase activity
0.34	GO:0005515	protein binding

0.52	GO:0045177	apical part of cell
0.48	GO:0043209	myelin sheath
0.44	GO:0005829	cytosol
0.42	GO:0005886	plasma membrane
0.39	GO:0005902	microvillus
0.38	GO:0030424	axon
0.37	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.30	GO:0016021	integral component of membrane

0.77

EC:4.2.1.1

GO:0004089

sp|P00974|BPT1_BOVIN
Pancreatic trypsin inhibitor
Search

0.59	Pancreatic trypsin inhibitor

0.76	GO:0010951	negative regulation of endopeptidase activity
0.44	GO:0006508	proteolysis
0.38	GO:0050878	regulation of body fluid levels
0.38	GO:0070495	negative regulation of thrombin-activated receptor signaling pathway
0.38	GO:1902572	negative regulation of serine-type peptidase activity
0.38	GO:1900003	regulation of serine-type endopeptidase activity
0.38	GO:0034111	negative regulation of homotypic cell-cell adhesion
0.37	GO:0002119	nematode larval development
0.37	GO:0050819	negative regulation of coagulation
0.37	GO:0061045	negative regulation of wound healing

0.79	GO:0004867	serine-type endopeptidase inhibitor activity
0.44	GO:0008233	peptidase activity
0.38	GO:0035375	zymogen binding
0.38	GO:0043199	sulfate binding
0.38	GO:0019870	potassium channel inhibitor activity
0.37	GO:0019862	IgA binding
0.37	GO:0002020	protease binding
0.37	GO:0046983	protein dimerization activity
0.35	GO:0042802	identical protein binding
0.35	GO:0005509	calcium ion binding

0.47	GO:0005576	extracellular region
0.39	GO:0097223	sperm part
0.38	GO:0097180	serine protease inhibitor complex
0.38	GO:0030141	secretory granule
0.34	GO:0042151	nematocyst
0.34	GO:0005886	plasma membrane
0.33	GO:0009986	cell surface
0.30	GO:0016021	integral component of membrane

0.44

GO:0008233

sp|P00975|IBPS_BOVIN
Serum basic protease inhibitor
Search

0.57	Serum basic protease inhibitor

0.76	GO:0010951	negative regulation of endopeptidase activity
0.43	GO:0006508	proteolysis
0.39	GO:0050878	regulation of body fluid levels
0.38	GO:0006030	chitin metabolic process
0.37	GO:0050817	coagulation
0.37	GO:0002119	nematode larval development
0.37	GO:0042060	wound healing
0.36	GO:0070495	negative regulation of thrombin-activated receptor signaling pathway
0.36	GO:0009792	embryo development ending in birth or egg hatching
0.36	GO:0048598	embryonic morphogenesis

0.79	GO:0004867	serine-type endopeptidase inhibitor activity
0.43	GO:0008233	peptidase activity
0.38	GO:0008061	chitin binding
0.38	GO:0019862	IgA binding
0.37	GO:0035375	zymogen binding
0.36	GO:0043199	sulfate binding
0.36	GO:0019870	potassium channel inhibitor activity
0.36	GO:0046983	protein dimerization activity
0.36	GO:0002020	protease binding
0.36	GO:0042802	identical protein binding

0.48	GO:0005576	extracellular region
0.39	GO:0097223	sperm part
0.38	GO:0030141	secretory granule
0.37	GO:0097180	serine protease inhibitor complex
0.34	GO:0005886	plasma membrane
0.33	GO:0009986	cell surface
0.30	GO:0016021	integral component of membrane

0.43

GO:0008233

sp|P00976|IBPC_BOVIN
Colostrum trypsin inhibitor
Search

ELP

0.95	Colostrum trypsin inhibitor

0.76	GO:0010951	negative regulation of endopeptidase activity
0.44	GO:0006508	proteolysis
0.40	GO:0006030	chitin metabolic process
0.39	GO:0007596	blood coagulation
0.38	GO:0030198	extracellular matrix organization
0.38	GO:1901318	negative regulation of flagellated sperm motility
0.37	GO:0090281	negative regulation of calcium ion import
0.37	GO:0042742	defense response to bacterium
0.35	GO:0051259	protein oligomerization
0.35	GO:0007275	multicellular organism development

0.79	GO:0004867	serine-type endopeptidase inhibitor activity
0.44	GO:0008233	peptidase activity
0.40	GO:0008061	chitin binding
0.38	GO:0005201	extracellular matrix structural constituent
0.33	GO:0005515	protein binding

0.54	GO:0005576	extracellular region
0.42	GO:0097223	sperm part
0.41	GO:0030141	secretory granule
0.37	GO:0009986	cell surface
0.34	GO:0043234	protein complex
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.44

GO:0008233

sp|P00978|AMBP_BOVIN
Protein AMBP
Search

AMBP

0.97	Alpha-1-microglobulin/bikunin precursor

0.76	GO:0010951	negative regulation of endopeptidase activity
0.43	GO:0018298	protein-chromophore linkage
0.38	GO:0030163	protein catabolic process
0.37	GO:0042167	heme catabolic process
0.37	GO:0046329	negative regulation of JNK cascade
0.36	GO:0007565	female pregnancy
0.35	GO:0050777	negative regulation of immune response
0.35	GO:0007155	cell adhesion
0.35	GO:0006898	receptor-mediated endocytosis
0.35	GO:0007018	microtubule-based movement

0.78	GO:0004867	serine-type endopeptidase inhibitor activity
0.69	GO:0019862	IgA binding
0.57	GO:0042803	protein homodimerization activity
0.50	GO:0020037	heme binding
0.38	GO:0046904	calcium oxalate binding
0.37	GO:0019855	calcium channel inhibitor activity
0.35	GO:0003777	microtubule motor activity
0.35	GO:0008017	microtubule binding
0.33	GO:0008233	peptidase activity
0.33	GO:0090729	toxin activity

0.54	GO:0031012	extracellular matrix
0.46	GO:0005886	plasma membrane
0.39	GO:0072562	blood microparticle
0.39	GO:0009986	cell surface
0.38	GO:0070062	extracellular exosome
0.35	GO:0043229	intracellular organelle
0.35	GO:0099512	supramolecular fiber
0.34	GO:0072556	other organism presynaptic membrane
0.33	GO:0043228	non-membrane-bounded organelle
0.33	GO:0044422	organelle part

0.33

GO:0008233

sp|P00996|ISK1_BOVIN
Serine protease inhibitor Kazal-type 1
Search

SPINK1

0.83	pancreatic secretory trypsin inhibitor

0.69	GO:0010951	negative regulation of endopeptidase activity
0.57	GO:1902572	negative regulation of serine-type peptidase activity
0.57	GO:1900003	regulation of serine-type endopeptidase activity
0.56	GO:0060046	regulation of acrosome reaction
0.51	GO:0010751	negative regulation of nitric oxide mediated signal transduction
0.49	GO:0090281	negative regulation of calcium ion import
0.49	GO:0048240	sperm capacitation
0.49	GO:2001256	regulation of store-operated calcium entry
0.49	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation
0.48	GO:0006508	proteolysis

0.71	GO:0004867	serine-type endopeptidase inhibitor activity
0.49	GO:0008233	peptidase activity
0.39	GO:0005509	calcium ion binding
0.39	GO:0043236	laminin binding
0.38	GO:0019870	potassium channel inhibitor activity
0.37	GO:0002020	protease binding
0.33	GO:0016301	kinase activity

0.50	GO:0005615	extracellular space
0.50	GO:0097223	sperm part
0.48	GO:0030141	secretory granule
0.38	GO:0090651	apical cytoplasm
0.37	GO:0005605	basal lamina
0.34	GO:0005829	cytosol
0.34	GO:0005886	plasma membrane
0.34	GO:0043234	protein complex

0.49

GO:0008233

sp|P01000|IAC1_BOVIN
Acrosin inhibitor 1
Search

0.83	Serine protease inhibitor Kazal-type 2

0.71	GO:0010951	negative regulation of endopeptidase activity
0.54	GO:1902572	negative regulation of serine-type peptidase activity
0.54	GO:1900003	regulation of serine-type endopeptidase activity
0.50	GO:0060046	regulation of acrosome reaction
0.45	GO:0002176	male germ cell proliferation
0.44	GO:0006508	proteolysis
0.44	GO:0007286	spermatid development
0.44	GO:0072520	seminiferous tubule development
0.42	GO:0009566	fertilization
0.41	GO:0043065	positive regulation of apoptotic process

0.72	GO:0004867	serine-type endopeptidase inhibitor activity
0.45	GO:0008233	peptidase activity
0.43	GO:0005509	calcium ion binding
0.42	GO:0032190	acrosin binding
0.41	GO:0002020	protease binding
0.37	GO:0050840	extracellular matrix binding
0.37	GO:0005518	collagen binding
0.36	GO:0005044	scavenger receptor activity
0.35	GO:0003968	RNA-directed 5'-3' RNA polymerase activity
0.34	GO:0016788	hydrolase activity, acting on ester bonds

0.50	GO:0097223	sperm part
0.49	GO:0005576	extracellular region
0.49	GO:0030141	secretory granule
0.42	GO:0097180	serine protease inhibitor complex
0.41	GO:0043005	neuron projection
0.30	GO:0016020	membrane

0.45

GO:0008233

sp|P01001|ISK6_BOVIN
Serine protease inhibitor Kazal-type 6
Search

SPINK6

0.97	Serine protease inhibitor Kazal-type 6

0.64	GO:1900004	negative regulation of serine-type endopeptidase activity
0.53	GO:0006508	proteolysis
0.39	GO:0070268	cornification
0.38	GO:0043113	receptor clustering
0.37	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway
0.34	GO:0007422	peripheral nervous system development
0.34	GO:0009952	anterior/posterior pattern specification
0.34	GO:0007409	axonogenesis
0.34	GO:0007417	central nervous system development

0.62	GO:0004867	serine-type endopeptidase inhibitor activity
0.53	GO:0008233	peptidase activity
0.39	GO:0005509	calcium ion binding
0.38	GO:0043236	laminin binding

0.50	GO:0005576	extracellular region
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.53

GO:0008233

sp|P01017|ANGT_BOVIN
Angiotensinogen (Fragment)
Search

0.10	Angiotensinogen (Fragment)

0.30	GO:0035296	regulation of tube diameter
0.30	GO:0051234	establishment of localization
0.30	GO:0009566	fertilization
0.30	GO:0009987	cellular process
0.30	GO:0003018	vascular process in circulatory system
0.30	GO:0008015	blood circulation

0.30

GO:0005576

extracellular region

sp|P01030|CO4_BOVIN
Complement C4 (Fragments)
Search

0.86	Sex-limited protein Slp(w7) alpha-gamma chain (Fragment)

0.64	GO:0010951	negative regulation of endopeptidase activity
0.43	GO:0006956	complement activation
0.42	GO:0006954	inflammatory response
0.42	GO:0002455	humoral immune response mediated by circulating immunoglobulin
0.40	GO:0045087	innate immune response
0.35	GO:0007566	embryo implantation

0.64

GO:0004866

endopeptidase inhibitor activity

0.70	GO:0005615	extracellular space
0.41	GO:0030425	dendrite
0.41	GO:0030424	axon
0.40	GO:0045202	synapse
0.39	GO:0030054	cell junction
0.33	GO:1903561	extracellular vesicle

sp|P01035|CYTC_BOVIN
Cystatin-C
Search

CST3

0.67	Cystatin-C

0.76	GO:0010951	negative regulation of endopeptidase activity
0.58	GO:0010711	negative regulation of collagen catabolic process
0.57	GO:0060311	negative regulation of elastin catabolic process
0.56	GO:0060313	negative regulation of blood vessel remodeling
0.56	GO:0010716	negative regulation of extracellular matrix disassembly
0.52	GO:2000116	regulation of cysteine-type endopeptidase activity
0.48	GO:0097435	supramolecular fiber organization
0.47	GO:0006952	defense response
0.46	GO:0042747	circadian sleep/wake cycle, REM sleep
0.44	GO:0060009	Sertoli cell development

0.83	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.60	GO:0002020	protease binding
0.53	GO:0001540	amyloid-beta binding
0.48	GO:0042802	identical protein binding
0.33	GO:0008233	peptidase activity

0.54	GO:0005615	extracellular space
0.43	GO:0005771	multivesicular body
0.42	GO:0005604	basement membrane
0.42	GO:0043025	neuronal cell body
0.42	GO:0043292	contractile fiber
0.42	GO:0030424	axon
0.41	GO:0031965	nuclear membrane
0.41	GO:0048471	perinuclear region of cytoplasm
0.41	GO:0005764	lysosome
0.40	GO:1903561	extracellular vesicle

0.33

GO:0008233

sp|P01044|KNG1_BOVIN
Kininogen-1
Search

KNG1

0.94	High molecular weight kininogen II

0.75	GO:0010951	negative regulation of endopeptidase activity
0.61	GO:0030195	negative regulation of blood coagulation
0.58	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.54	GO:0007162	negative regulation of cell adhesion
0.46	GO:0042311	vasodilation
0.44	GO:0006954	inflammatory response
0.42	GO:0007596	blood coagulation
0.37	GO:0002576	platelet degranulation
0.37	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.36	GO:0072376	protein activation cascade

0.82	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.51	GO:0005102	receptor binding
0.36	GO:0008201	heparin binding
0.34	GO:0008270	zinc ion binding
0.32	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.32	GO:0002020	protease binding
0.32	GO:0051537	2 iron, 2 sulfur cluster binding
0.31	GO:0043565	sequence-specific DNA binding
0.31	GO:0009055	electron transfer activity

0.55	GO:0005615	extracellular space
0.52	GO:0031012	extracellular matrix
0.37	GO:0031093	platelet alpha granule lumen
0.36	GO:0005788	endoplasmic reticulum lumen
0.36	GO:1903561	extracellular vesicle
0.33	GO:0005886	plasma membrane
0.32	GO:0043204	perikaryon
0.31	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|P01045|KNG2_BOVIN
Kininogen-2
Search

KNG1

0.93	High molecular weight kininogen II

0.75	GO:0010951	negative regulation of endopeptidase activity
0.62	GO:0030195	negative regulation of blood coagulation
0.59	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.54	GO:0007162	negative regulation of cell adhesion
0.46	GO:0042311	vasodilation
0.44	GO:0006954	inflammatory response
0.43	GO:0007596	blood coagulation
0.37	GO:0002576	platelet degranulation
0.37	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.36	GO:0072376	protein activation cascade

0.82	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.51	GO:0005102	receptor binding
0.36	GO:0008201	heparin binding
0.34	GO:0008270	zinc ion binding
0.32	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.32	GO:0002020	protease binding
0.32	GO:0051537	2 iron, 2 sulfur cluster binding
0.31	GO:0043565	sequence-specific DNA binding
0.31	GO:0009055	electron transfer activity

0.55	GO:0005615	extracellular space
0.52	GO:0031012	extracellular matrix
0.37	GO:0031093	platelet alpha granule lumen
0.36	GO:0005788	endoplasmic reticulum lumen
0.36	GO:1903561	extracellular vesicle
0.33	GO:0005886	plasma membrane
0.32	GO:0043204	perikaryon
0.31	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|P01096|ATIF1_BOVIN
ATPase inhibitor, mitochondrial
Search

ATPIF1

0.97	Mitochondrial ATPase inhibitory factor 1

0.80	GO:0032780	negative regulation of ATPase activity
0.58	GO:0051882	mitochondrial depolarization
0.56	GO:1904925	positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization
0.56	GO:1901030	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
0.55	GO:0001937	negative regulation of endothelial cell proliferation
0.55	GO:0030218	erythrocyte differentiation
0.54	GO:1903578	regulation of ATP metabolic process
0.54	GO:1903214	regulation of protein targeting to mitochondrion
0.52	GO:1903052	positive regulation of proteolysis involved in cellular protein catabolic process
0.51	GO:0006783	heme biosynthetic process

0.80	GO:0042030	ATPase inhibitor activity
0.58	GO:0043532	angiostatin binding
0.58	GO:0051117	ATPase binding
0.49	GO:0030272	5-formyltetrahydrofolate cyclo-ligase activity
0.42	GO:0005516	calmodulin binding
0.41	GO:0042803	protein homodimerization activity
0.33	GO:0004588	orotate phosphoribosyltransferase activity
0.33	GO:0004590	orotidine-5'-phosphate decarboxylase activity
0.33	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters

0.60	GO:0005739	mitochondrion
0.50	GO:0009986	cell surface
0.48	GO:0045259	proton-transporting ATP synthase complex
0.44	GO:0019866	organelle inner membrane

0.49	EC:6.3.3.2	GO:0030272
0.49	KEGG:R02301	GO:0030272

sp|P01131|LDLR_BOVIN
Low-density lipoprotein receptor
Search

LDLR

0.87	Low density lipoprotein receptor a

0.57	GO:0090118	receptor-mediated endocytosis involved in cholesterol transport
0.57	GO:0061889	negative regulation of astrocyte activation
0.56	GO:1903979	negative regulation of microglial cell activation
0.56	GO:1905167	positive regulation of lysosomal protein catabolic process
0.56	GO:0010899	regulation of phosphatidylcholine catabolic process
0.56	GO:0061771	response to caloric restriction
0.56	GO:1905907	negative regulation of amyloid fibril formation
0.56	GO:0010986	positive regulation of lipoprotein particle clearance
0.56	GO:1900223	positive regulation of amyloid-beta clearance
0.55	GO:0097242	amyloid-beta clearance

0.69	GO:0005509	calcium ion binding
0.57	GO:0005041	low-density lipoprotein receptor activity
0.55	GO:0030169	low-density lipoprotein particle binding
0.55	GO:0030229	very-low-density lipoprotein particle receptor activity
0.53	GO:0001540	amyloid-beta binding
0.51	GO:0002020	protease binding
0.47	GO:0042802	identical protein binding
0.37	GO:0032050	clathrin heavy chain binding
0.37	GO:0104005	hijacked molecular function
0.32	GO:0004930	G-protein coupled receptor activity

0.55	GO:1990666	PCSK9-LDLR complex
0.55	GO:0097443	sorting endosome
0.52	GO:0005770	late endosome
0.52	GO:0005769	early endosome
0.51	GO:0005905	clathrin-coated pit
0.51	GO:0005764	lysosome
0.51	GO:0016323	basolateral plasma membrane
0.50	GO:0045177	apical part of cell
0.50	GO:0009897	external side of plasma membrane
0.50	GO:0036477	somatodendritic compartment

sp|P01154|POPI_BOVIN
Posterior pituitary peptide
Search

0.40	Posterior pituitary peptide

sp|P01156|NEUT_BOVIN
Neurotensin/neuromedin N
Search

NTS

0.97	Neurotensin/neuromedin N

0.76	GO:0010469	regulation of receptor activity
0.43	GO:0050880	regulation of blood vessel size
0.37	GO:0097332	response to antipsychotic drug
0.37	GO:0051412	response to corticosterone
0.37	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.37	GO:0071285	cellular response to lithium ion
0.37	GO:0071549	cellular response to dexamethasone stimulus
0.37	GO:0001975	response to amphetamine
0.36	GO:1990090	cellular response to nerve growth factor stimulus
0.36	GO:0042220	response to cocaine

0.85

GO:0005184

neuropeptide hormone activity

0.66	GO:0005576	extracellular region
0.51	GO:0043679	axon terminus
0.42	GO:0030133	transport vesicle
0.36	GO:0043025	neuronal cell body
0.30	GO:0016020	membrane

sp|P01175|NEU1_BOVIN
Oxytocin-neurophysin 1
Search

OXT

0.96	Prepropeptide for oxytocin and neurophysin

0.76	GO:0010469	regulation of receptor activity
0.52	GO:0032094	response to food
0.50	GO:0070528	protein kinase C signaling
0.50	GO:0090201	negative regulation of release of cytochrome c from mitochondria
0.50	GO:0070371	ERK1 and ERK2 cascade
0.49	GO:0009612	response to mechanical stimulus
0.48	GO:0033138	positive regulation of peptidyl-serine phosphorylation
0.48	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.46	GO:0006915	apoptotic process
0.45	GO:0002125	maternal aggressive behavior

0.86	GO:0005185	neurohypophyseal hormone activity
0.53	GO:0031894	V1A vasopressin receptor binding
0.49	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.44	GO:0031855	oxytocin receptor binding
0.41	GO:0004871	signal transducer activity
0.41	GO:0004672	protein kinase activity
0.40	GO:0031895	V1B vasopressin receptor binding
0.36	GO:0031896	V2 vasopressin receptor binding
0.34	GO:0052795	exo-alpha-(2->6)-sialidase activity
0.34	GO:0052796	exo-alpha-(2->8)-sialidase activity

0.66	GO:0005576	extracellular region
0.43	GO:0043005	neuron projection
0.43	GO:0120038	plasma membrane bounded cell projection part
0.42	GO:0030141	secretory granule
0.40	GO:0036477	somatodendritic compartment
0.40	GO:0098793	presynapse
0.38	GO:0044297	cell body
0.34	GO:0030665	clathrin-coated vesicle membrane
0.33	GO:0005829	cytosol
0.30	GO:0044425	membrane part

0.34

EC:3.2.1.18

GO:0052795

sp|P01180|NEU2_BOVIN
Vasopressin-neurophysin 2-copeptin
Search

0.95	Prepropeptide for oxytocin and neurophysin

0.76	GO:0010469	regulation of receptor activity
0.52	GO:0070528	protein kinase C signaling
0.51	GO:0090201	negative regulation of release of cytochrome c from mitochondria
0.51	GO:0070371	ERK1 and ERK2 cascade
0.50	GO:0033138	positive regulation of peptidyl-serine phosphorylation
0.50	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.48	GO:0032094	response to food
0.47	GO:0006915	apoptotic process
0.45	GO:0009612	response to mechanical stimulus
0.45	GO:0010628	positive regulation of gene expression

0.86	GO:0005185	neurohypophyseal hormone activity
0.54	GO:0031894	V1A vasopressin receptor binding
0.51	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.42	GO:0004871	signal transducer activity
0.42	GO:0004672	protein kinase activity
0.41	GO:0031855	oxytocin receptor binding
0.40	GO:0031895	V1B vasopressin receptor binding
0.36	GO:0031896	V2 vasopressin receptor binding
0.33	GO:0052795	exo-alpha-(2->6)-sialidase activity
0.33	GO:0052796	exo-alpha-(2->8)-sialidase activity

0.66	GO:0005576	extracellular region
0.42	GO:0043005	neuron projection
0.42	GO:0120038	plasma membrane bounded cell projection part
0.41	GO:0030141	secretory granule
0.40	GO:0036477	somatodendritic compartment
0.38	GO:0044297	cell body
0.38	GO:0098793	presynapse
0.35	GO:0030665	clathrin-coated vesicle membrane
0.34	GO:0005829	cytosol
0.30	GO:0044425	membrane part

0.33	EC:3.2.1.18	GO:0052795
0.33	KEGG:R03876	GO:0004842

sp|P01190|COLI_BOVIN
Pro-opiomelanocortin
Search

POMC

0.60	Proopiomelanocortin (Adrenocorticotropin/ beta-lipotropin/ alpha-melanocyte stimulating hormone/ beta-melanocyte stimulating hormone/ beta-endorphin)

0.75	GO:0010469	regulation of receptor activity
0.58	GO:2000852	regulation of corticosterone secretion
0.54	GO:0032098	regulation of appetite
0.54	GO:0032720	negative regulation of tumor necrosis factor production
0.54	GO:0070873	regulation of glycogen metabolic process
0.54	GO:0033059	cellular pigmentation
0.52	GO:0008217	regulation of blood pressure
0.51	GO:0042593	glucose homeostasis
0.49	GO:0007267	cell-cell signaling
0.49	GO:0045944	positive regulation of transcription by RNA polymerase II

0.78	GO:0005179	hormone activity
0.57	GO:0070996	type 1 melanocortin receptor binding
0.57	GO:0031781	type 3 melanocortin receptor binding
0.57	GO:0031782	type 4 melanocortin receptor binding
0.32	GO:0009008	DNA-methyltransferase activity
0.32	GO:0008270	zinc ion binding

0.66	GO:0005576	extracellular region
0.52	GO:0030141	secretory granule
0.36	GO:0060205	cytoplasmic vesicle lumen
0.36	GO:0031907	microbody lumen
0.35	GO:0044439	peroxisomal part
0.30	GO:0016020	membrane

0.32

GO:0009008

sp|P01211|PENK_BOVIN
Proenkephalin-A
Search

PENK

0.97	Proenkephalin-A-A

0.80	GO:0007218	neuropeptide signaling pathway
0.62	GO:0010469	regulation of receptor activity
0.61	GO:0002118	aggressive behavior
0.60	GO:0001964	startle response
0.60	GO:0001662	behavioral fear response
0.59	GO:0019233	sensory perception of pain
0.57	GO:0007626	locomotory behavior
0.46	GO:0007268	chemical synaptic transmission
0.41	GO:0051867	general adaptation syndrome, behavioral process
0.41	GO:2000987	positive regulation of behavioral fear response

0.72	GO:0001515	opioid peptide activity
0.51	GO:0031628	opioid receptor binding
0.48	GO:0005184	neuropeptide hormone activity
0.35	GO:0016849	phosphorus-oxygen lyase activity
0.33	GO:0090729	toxin activity

0.54	GO:0005576	extracellular region
0.49	GO:0043679	axon terminus
0.47	GO:0043025	neuronal cell body
0.47	GO:0030425	dendrite
0.41	GO:0032280	symmetric synapse
0.41	GO:0070852	cell body fiber
0.39	GO:0030424	axon
0.39	GO:0005886	plasma membrane
0.35	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0016021	integral component of membrane

0.35

EC:4.6

GO:0016849

sp|P01217|GLHA_BOVIN
Glycoprotein hormones alpha chain
Search

CGA

0.93	Glycoprotein hormones alpha chain

0.76	GO:0010469	regulation of receptor activity
0.54	GO:0046884	follicle-stimulating hormone secretion
0.53	GO:0032275	luteinizing hormone secretion
0.52	GO:0006590	thyroid hormone generation
0.51	GO:0030878	thyroid gland development
0.51	GO:0046621	negative regulation of organ growth
0.49	GO:0008406	gonad development
0.48	GO:0048589	developmental growth
0.47	GO:0032870	cellular response to hormone stimulus
0.34	GO:0006702	androgen biosynthetic process

0.79	GO:0005179	hormone activity
0.44	GO:0046982	protein heterodimerization activity
0.35	GO:0008083	growth factor activity

0.66	GO:0005576	extracellular region
0.30	GO:0016020	membrane

sp|P01223|TSHB_BOVIN
Thyrotropin subunit beta
Search

TSHB

0.91	Thyroid stimulating hormone beta subunit

0.76	GO:0010469	regulation of receptor activity
0.40	GO:0010033	response to organic substance
0.39	GO:0071495	cellular response to endogenous stimulus
0.39	GO:0007267	cell-cell signaling
0.38	GO:0007186	G-protein coupled receptor signaling pathway
0.37	GO:0033273	response to vitamin
0.37	GO:0043627	response to estrogen
0.37	GO:0051592	response to calcium ion
0.37	GO:0070887	cellular response to chemical stimulus

0.79

GO:0005179

hormone activity

0.66	GO:0005576	extracellular region
0.34	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

sp|P01239|PRL_BOVIN
Prolactin
Search

PRL

0.92	Prolactin variant

0.76	GO:0010469	regulation of receptor activity
0.54	GO:1902895	positive regulation of pri-miRNA transcription by RNA polymerase II
0.53	GO:0001937	negative regulation of endothelial cell proliferation
0.53	GO:0046427	positive regulation of JAK-STAT cascade
0.52	GO:0040014	regulation of multicellular organism growth
0.50	GO:0007595	lactation
0.48	GO:0030072	peptide hormone secretion
0.48	GO:0045723	positive regulation of fatty acid biosynthetic process
0.45	GO:0043066	negative regulation of apoptotic process
0.42	GO:1903489	positive regulation of lactation

0.79	GO:0005179	hormone activity
0.51	GO:0005148	prolactin receptor binding
0.35	GO:0005125	cytokine activity

0.66	GO:0005576	extracellular region
0.35	GO:0031904	endosome lumen
0.35	GO:0005788	endoplasmic reticulum lumen
0.34	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

sp|P01246|SOMA_BOVIN
Somatotropin
Search

0.79	Growth hormone, variant B

0.76	GO:0010469	regulation of receptor activity
0.58	GO:1903408	positive regulation of sodium:potassium-exchanging ATPase activity
0.57	GO:0030073	insulin secretion
0.56	GO:0032930	positive regulation of superoxide anion generation
0.55	GO:0010960	magnesium ion homeostasis
0.55	GO:0055078	sodium ion homeostasis
0.55	GO:0042538	hyperosmotic salinity response
0.53	GO:0032094	response to food
0.51	GO:0055074	calcium ion homeostasis
0.49	GO:0040018	positive regulation of multicellular organism growth

0.85	GO:0005131	growth hormone receptor binding
0.79	GO:0005179	hormone activity
0.40	GO:0046872	metal ion binding
0.35	GO:0005148	prolactin receptor binding
0.35	GO:0004346	glucose-6-phosphatase activity
0.34	GO:0008083	growth factor activity
0.33	GO:0004888	transmembrane signaling receptor activity

0.73	GO:0005615	extracellular space
0.47	GO:0030141	secretory granule
0.47	GO:0005802	trans-Golgi network
0.41	GO:0005634	nucleus
0.39	GO:0005886	plasma membrane
0.36	GO:0031012	extracellular matrix
0.35	GO:0070195	growth hormone receptor complex
0.35	GO:0005829	cytosol
0.34	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

0.35	EC:3.1.3.9	GO:0004346
0.35	KEGG:R00303	GO:0004346

sp|P01249|THP1_BOVIN
Thymopoietin-1
Search

0.95	Thymopoietin-1

0.43	GO:0031468	nuclear envelope reassembly
0.40	GO:1903047	mitotic cell cycle process
0.38	GO:1903506	regulation of nucleic acid-templated transcription
0.38	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.37	GO:0010468	regulation of gene expression
0.37	GO:0010469	regulation of receptor activity

0.55	GO:0003677	DNA binding
0.45	GO:0045296	cadherin binding
0.40	GO:0003682	chromatin binding
0.39	GO:0005521	lamin binding
0.37	GO:0005179	hormone activity
0.35	GO:0042802	identical protein binding

0.44	GO:0005635	nuclear envelope
0.43	GO:0005694	chromosome
0.39	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0031090	organelle membrane
0.34	GO:0098827	endoplasmic reticulum subcompartment
0.30	GO:0031224	intrinsic component of membrane

sp|P01250|THP2_BOVIN
Thymopoietin-2
Search

0.95	Thymopoietin-2

0.43	GO:0031468	nuclear envelope reassembly
0.40	GO:1903047	mitotic cell cycle process
0.38	GO:1903506	regulation of nucleic acid-templated transcription
0.38	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.37	GO:0010468	regulation of gene expression
0.37	GO:0010469	regulation of receptor activity

0.55	GO:0003677	DNA binding
0.45	GO:0045296	cadherin binding
0.40	GO:0003682	chromatin binding
0.39	GO:0005521	lamin binding
0.37	GO:0005179	hormone activity
0.35	GO:0042802	identical protein binding

0.44	GO:0005635	nuclear envelope
0.43	GO:0005694	chromosome
0.39	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0031090	organelle membrane
0.34	GO:0098827	endoplasmic reticulum subcompartment
0.30	GO:0031224	intrinsic component of membrane

sp|P01251|THPS_BOVIN
Splenin
Search

0.95	Thymopoietin-2

0.43	GO:0031468	nuclear envelope reassembly
0.39	GO:1903047	mitotic cell cycle process
0.38	GO:1903506	regulation of nucleic acid-templated transcription
0.38	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.38	GO:0010468	regulation of gene expression
0.37	GO:0010469	regulation of receptor activity

0.55	GO:0003677	DNA binding
0.45	GO:0045296	cadherin binding
0.40	GO:0003682	chromatin binding
0.39	GO:0005521	lamin binding
0.37	GO:0005179	hormone activity
0.35	GO:0042802	identical protein binding

0.44	GO:0005635	nuclear envelope
0.43	GO:0005694	chromosome
0.39	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0031090	organelle membrane
0.34	GO:0098827	endoplasmic reticulum subcompartment
0.30	GO:0031224	intrinsic component of membrane

sp|P01252|PTMA_BOVIN
Prothymosin alpha
Search

PTMA

0.96	Prothymosin alpha

0.61	GO:0043486	histone exchange
0.41	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.41	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.40	GO:0008283	cell proliferation
0.39	GO:0045944	positive regulation of transcription by RNA polymerase II
0.39	GO:0030154	cell differentiation
0.38	GO:0016024	CDP-diacylglycerol biosynthetic process
0.38	GO:0032049	cardiolipin biosynthetic process
0.36	GO:0006351	transcription, DNA-templated

0.66	GO:0033613	activating transcription factor binding
0.59	GO:0042393	histone binding
0.39	GO:0035091	phosphatidylinositol binding
0.38	GO:0004605	phosphatidate cytidylyltransferase activity
0.37	GO:0030554	adenyl nucleotide binding
0.37	GO:0032555	purine ribonucleotide binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0003676	nucleic acid binding

0.59	GO:0005654	nucleoplasm
0.58	GO:0005829	cytosol
0.45	GO:0070062	extracellular exosome
0.37	GO:0031011	Ino80 complex
0.36	GO:0031966	mitochondrial membrane
0.36	GO:0019866	organelle inner membrane

0.38

EC:2.7.7.41

GO:0004605

sp|P01260|CALC_BOVIN
Calcitonin
Search

CALCA

0.73	Calcitonin

0.76

GO:0010469

regulation of receptor activity

0.79

GO:0005179

hormone activity

0.66

GO:0005576

extracellular region

sp|P01267|THYG_BOVIN
Thyroglobulin
Search

0.55	Thyroglobulin

0.75	GO:0015705	iodide transport
0.72	GO:0042403	thyroid hormone metabolic process
0.71	GO:0031641	regulation of myelination
0.71	GO:0030878	thyroid gland development
0.44	GO:2001141	regulation of RNA biosynthetic process
0.44	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.43	GO:0010468	regulation of gene expression
0.35	GO:0097105	presynaptic membrane assembly
0.35	GO:0097104	postsynaptic membrane assembly
0.35	GO:0007158	neuron cell-cell adhesion

0.35	GO:0005102	receptor binding
0.34	GO:0030545	receptor regulator activity
0.34	GO:0052689	carboxylic ester hydrolase activity
0.33	GO:0004872	receptor activity
0.30	GO:0042393	histone binding

0.61	GO:0005576	extracellular region
0.46	GO:0005634	nucleus
0.34	GO:0009986	cell surface
0.34	GO:0045202	synapse
0.33	GO:0005887	integral component of plasma membrane

0.34	EC:3.1.1 EC:3.1.1.1	GO:0052689
0.34	KEGG:R00630	GO:0052689

sp|P01268|PTHY_BOVIN
Parathyroid hormone
Search

PTH

0.97	Parathyroid hormone

0.80	GO:0006874	cellular calcium ion homeostasis
0.79	GO:0046326	positive regulation of glucose import
0.76	GO:0010469	regulation of receptor activity
0.73	GO:0090290	positive regulation of osteoclast proliferation
0.72	GO:0071866	negative regulation of apoptotic process in bone marrow
0.72	GO:0060732	positive regulation of inositol phosphate biosynthetic process
0.72	GO:0045725	positive regulation of glycogen biosynthetic process
0.72	GO:0071864	positive regulation of cell proliferation in bone marrow
0.71	GO:0007202	activation of phospholipase C activity
0.70	GO:0030819	positive regulation of cAMP biosynthetic process

0.79	GO:0005179	hormone activity
0.76	GO:0031856	parathyroid hormone receptor binding
0.72	GO:0051428	peptide hormone receptor binding
0.68	GO:0047485	protein N-terminus binding
0.68	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding

0.66	GO:0005576	extracellular region
0.40	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|P01272|GLUC_BOVIN
Glucagon
Search

GCG

0.96	Preproglucagon A

0.76	GO:0010469	regulation of receptor activity
0.61	GO:0032099	negative regulation of appetite
0.57	GO:0010737	protein kinase A signaling
0.56	GO:0035948	positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter
0.56	GO:1900118	negative regulation of execution phase of apoptosis
0.56	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus
0.56	GO:0090280	positive regulation of calcium ion import
0.56	GO:0051571	positive regulation of histone H3-K4 methylation
0.55	GO:0010800	positive regulation of peptidyl-threonine phosphorylation
0.54	GO:0033138	positive regulation of peptidyl-serine phosphorylation

0.79	GO:0005179	hormone activity
0.50	GO:0042802	identical protein binding
0.48	GO:0031769	glucagon receptor binding
0.37	GO:0017171	serine hydrolase activity
0.36	GO:0070011	peptidase activity, acting on L-amino acid peptides
0.34	GO:0004386	helicase activity
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0003677	DNA binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0008144	drug binding

0.66	GO:0005576	extracellular region
0.38	GO:0005737	cytoplasm
0.36	GO:0031983	vesicle lumen
0.35	GO:0097708	intracellular vesicle
0.34	GO:0012505	endomembrane system
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|P01289|TKN1_BOVIN
Protachykinin-1
Search

0.73	Tachykinin precursor 1

0.85	GO:0007217	tachykinin receptor signaling pathway
0.50	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.49	GO:0006954	inflammatory response
0.49	GO:1990090	cellular response to nerve growth factor stimulus
0.49	GO:0048265	response to pain
0.48	GO:0019233	sensory perception of pain
0.43	GO:0007267	cell-cell signaling
0.43	GO:0007218	neuropeptide signaling pathway

0.41

GO:0005102

receptor binding

0.47	GO:0005576	extracellular region
0.47	GO:0043025	neuronal cell body
0.46	GO:0030424	axon

sp|P01302|PAHO_BOVIN
Pancreatic prohormone
Search

PPY

0.88	Pancreatic polypeptide

0.76	GO:0010469	regulation of receptor activity
0.46	GO:0032098	regulation of appetite
0.45	GO:0007631	feeding behavior
0.45	GO:0007586	digestion
0.44	GO:0007218	neuropeptide signaling pathway
0.43	GO:0007267	cell-cell signaling

0.79	GO:0005179	hormone activity
0.50	GO:0001664	G-protein coupled receptor binding

0.66	GO:0005576	extracellular region
0.35	GO:0005737	cytoplasm

sp|P01317|INS_BOVIN
Insulin
Search

INS

0.96

Insulin

0.76	GO:0010469	regulation of receptor activity
0.70	GO:0006006	glucose metabolic process
0.51	GO:0010243	response to organonitrogen compound
0.50	GO:0050995	negative regulation of lipid catabolic process
0.50	GO:0045818	negative regulation of glycogen catabolic process
0.50	GO:0033861	negative regulation of NAD(P)H oxidase activity
0.49	GO:1902952	positive regulation of dendritic spine maintenance
0.49	GO:0060266	negative regulation of respiratory burst involved in inflammatory response
0.49	GO:0046628	positive regulation of insulin receptor signaling pathway
0.49	GO:2000252	negative regulation of feeding behavior

0.79	GO:0005179	hormone activity
0.54	GO:0005159	insulin-like growth factor receptor binding
0.51	GO:0005158	insulin receptor binding
0.48	GO:0002020	protease binding
0.44	GO:0042802	identical protein binding
0.36	GO:0051087	chaperone binding

0.66	GO:0005576	extracellular region
0.41	GO:0030141	secretory granule
0.39	GO:0060205	cytoplasmic vesicle lumen
0.37	GO:0005829	cytosol
0.36	GO:0005732	small nucleolar ribonucleoprotein complex
0.36	GO:0031904	endosome lumen
0.36	GO:0005796	Golgi lumen
0.35	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane
0.35	GO:0005788	endoplasmic reticulum lumen
0.35	GO:0030133	transport vesicle

sp|P01352|GAST_BOVIN
Gastrin
Search

GAST

0.97

Gastrin

0.74	GO:0010469	regulation of receptor activity
0.65	GO:0032094	response to food
0.50	GO:0007186	G-protein coupled receptor signaling pathway

0.78

GO:0005179

hormone activity

0.66

GO:0005576

extracellular region

sp|P01576|IFNB2_BOVIN
Interferon beta-2
Search

IFNB1

0.96	Interferon beta

0.77	GO:0051607	defense response to virus
0.75	GO:0010469	regulation of receptor activity
0.64	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein
0.62	GO:0043330	response to exogenous dsRNA
0.61	GO:0002285	lymphocyte activation involved in immune response
0.61	GO:0042113	B cell activation
0.58	GO:0019221	cytokine-mediated signaling pathway
0.57	GO:0045087	innate immune response
0.57	GO:2000552	negative regulation of T-helper 2 cell cytokine production
0.56	GO:0046651	lymphocyte proliferation

0.80	GO:0005125	cytokine activity
0.79	GO:0005126	cytokine receptor binding
0.53	GO:0008811	chloramphenicol O-acetyltransferase activity
0.51	GO:0032403	protein complex binding

0.73

GO:0005615

extracellular space

0.53	EC:2.3.1.28	GO:0008811
0.53	KEGG:R03065	GO:0008811

sp|P01577|IFNB3_BOVIN
Interferon beta-3
Search

IFNB1

0.97	Interferon beta

0.77	GO:0051607	defense response to virus
0.75	GO:0010469	regulation of receptor activity
0.64	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein
0.62	GO:0043330	response to exogenous dsRNA
0.61	GO:0002285	lymphocyte activation involved in immune response
0.61	GO:0042113	B cell activation
0.58	GO:0019221	cytokine-mediated signaling pathway
0.57	GO:0045087	innate immune response
0.57	GO:2000552	negative regulation of T-helper 2 cell cytokine production
0.56	GO:0030101	natural killer cell activation

0.80	GO:0005125	cytokine activity
0.79	GO:0005126	cytokine receptor binding
0.53	GO:0008811	chloramphenicol O-acetyltransferase activity
0.51	GO:0032403	protein complex binding

0.73

GO:0005615

extracellular space

0.53	EC:2.3.1.28	GO:0008811
0.53	KEGG:R03065	GO:0008811

sp|P01578|IFNB1_BOVIN
Interferon beta-1
Search

IFNB1

0.97	Interferon beta

0.77	GO:0051607	defense response to virus
0.75	GO:0010469	regulation of receptor activity
0.65	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein
0.63	GO:0043330	response to exogenous dsRNA
0.62	GO:0002285	lymphocyte activation involved in immune response
0.62	GO:0042113	B cell activation
0.59	GO:2000552	negative regulation of T-helper 2 cell cytokine production
0.59	GO:0019221	cytokine-mediated signaling pathway
0.58	GO:0045087	innate immune response
0.57	GO:0035458	cellular response to interferon-beta

0.80	GO:0005125	cytokine activity
0.79	GO:0005126	cytokine receptor binding
0.54	GO:0008811	chloramphenicol O-acetyltransferase activity
0.51	GO:0032403	protein complex binding

0.73

GO:0005615

extracellular space

0.54	EC:2.3.1.28	GO:0008811
0.54	KEGG:R03065	GO:0008811

sp|P01888|B2MG_BOVIN
Beta-2-microglobulin
Search

B2M

0.87	Beta-2-microglobulin

0.81	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I
0.74	GO:0006955	immune response
0.56	GO:1904440	positive regulation of ferrous iron import across plasma membrane
0.56	GO:1904434	positive regulation of ferrous iron binding
0.56	GO:1904435	regulation of transferrin receptor binding
0.56	GO:0071283	cellular response to iron(III) ion
0.56	GO:0002481	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
0.55	GO:1900122	positive regulation of receptor binding
0.55	GO:0002726	positive regulation of T cell cytokine production
0.55	GO:1900121	negative regulation of receptor binding

0.48	GO:0042802	identical protein binding
0.32	GO:0046872	metal ion binding

0.81	GO:0042612	MHC class I protein complex
0.66	GO:0005576	extracellular region
0.54	GO:1990712	HFE-transferrin receptor complex
0.50	GO:0009897	external side of plasma membrane
0.47	GO:0005794	Golgi apparatus
0.46	GO:0005829	cytosol
0.37	GO:0030670	phagocytic vesicle membrane
0.36	GO:0005925	focal adhesion
0.36	GO:0031905	early endosome lumen
0.35	GO:1904724	tertiary granule lumen

sp|P01966|HBA_BOVIN
Hemoglobin subunit alpha
Search

0.76	Hemoglobin subunit alpha

0.79	GO:0015671	oxygen transport
0.36	GO:0048821	erythrocyte development
0.36	GO:0051291	protein heterooligomerization
0.36	GO:0098869	cellular oxidant detoxification
0.36	GO:0042542	response to hydrogen peroxide
0.35	GO:0001701	in utero embryonic development
0.35	GO:0010942	positive regulation of cell death
0.35	GO:0042744	hydrogen peroxide catabolic process
0.35	GO:0035634	response to stilbenoid
0.34	GO:0015701	bicarbonate transport

0.80	GO:0005344	oxygen carrier activity
0.79	GO:0019825	oxygen binding
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.40	GO:0031720	haptoglobin binding
0.36	GO:0004601	peroxidase activity

0.83	GO:0005833	hemoglobin complex
0.39	GO:0031838	haptoglobin-hemoglobin complex
0.37	GO:0022627	cytosolic small ribosomal subunit
0.36	GO:0005615	extracellular space
0.35	GO:0071682	endocytic vesicle lumen
0.34	GO:0043209	myelin sheath
0.34	GO:1903561	extracellular vesicle
0.30	GO:0016020	membrane

0.36	EC:1.11.1.7	GO:0004601
0.36	KEGG:R03532	GO:0004601

sp|P02070|HBB_BOVIN
Hemoglobin subunit beta
Search

HBB

0.83	Hemoglobin fetal subunit beta

0.79	GO:0015671	oxygen transport
0.42	GO:0070293	renal absorption
0.42	GO:0051291	protein heterooligomerization
0.41	GO:0042542	response to hydrogen peroxide
0.40	GO:0010942	positive regulation of cell death
0.40	GO:0042744	hydrogen peroxide catabolic process
0.38	GO:0098869	cellular oxidant detoxification
0.36	GO:0007596	blood coagulation
0.35	GO:0030185	nitric oxide transport
0.35	GO:0043312	neutrophil degranulation

0.80	GO:0005344	oxygen carrier activity
0.79	GO:0019825	oxygen binding
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.44	GO:0031720	haptoglobin binding
0.42	GO:0030492	hemoglobin binding
0.39	GO:0004601	peroxidase activity

0.83	GO:0005833	hemoglobin complex
0.44	GO:0031838	haptoglobin-hemoglobin complex
0.39	GO:0005615	extracellular space
0.35	GO:0071682	endocytic vesicle lumen
0.35	GO:1904724	tertiary granule lumen
0.35	GO:1904813	ficolin-1-rich granule lumen
0.34	GO:1903561	extracellular vesicle

0.39	EC:1.11.1.7	GO:0004601
0.39	KEGG:R03532	GO:0004601

sp|P02081|HBBF_BOVIN
Hemoglobin fetal subunit beta
Search

HBB

0.86	Hemoglobin fetal subunit beta

0.79	GO:0015671	oxygen transport
0.43	GO:0070293	renal absorption
0.42	GO:0051291	protein heterooligomerization
0.41	GO:0042542	response to hydrogen peroxide
0.40	GO:0010942	positive regulation of cell death
0.40	GO:0042744	hydrogen peroxide catabolic process
0.38	GO:0098869	cellular oxidant detoxification
0.35	GO:0030185	nitric oxide transport
0.34	GO:0043312	neutrophil degranulation
0.34	GO:0070527	platelet aggregation

0.80	GO:0005344	oxygen carrier activity
0.79	GO:0019825	oxygen binding
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.44	GO:0031720	haptoglobin binding
0.42	GO:0030492	hemoglobin binding
0.39	GO:0004601	peroxidase activity

0.83	GO:0005833	hemoglobin complex
0.44	GO:0031838	haptoglobin-hemoglobin complex
0.39	GO:0005615	extracellular space
0.35	GO:0071682	endocytic vesicle lumen
0.35	GO:1904724	tertiary granule lumen
0.35	GO:1904813	ficolin-1-rich granule lumen
0.34	GO:1903561	extracellular vesicle

0.39	EC:1.11.1.7	GO:0004601
0.39	KEGG:R03532	GO:0004601

sp|P02192|MYG_BOVIN
Myoglobin
Search

0.83

Myoglobin

0.79	GO:0015671	oxygen transport
0.46	GO:0043353	enucleate erythrocyte differentiation
0.44	GO:0050873	brown fat cell differentiation
0.44	GO:0001666	response to hypoxia
0.43	GO:0007507	heart development
0.41	GO:0031444	slow-twitch skeletal muscle fiber contraction
0.39	GO:0042542	response to hydrogen peroxide
0.37	GO:0009725	response to hormone

0.80	GO:0005344	oxygen carrier activity
0.79	GO:0019825	oxygen binding
0.63	GO:0020037	heme binding
0.54	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.35	GO:0070062	extracellular exosome
0.33	GO:0005829	cytosol

sp|P02253|H12_BOVIN
Histone H1.2
Search

0.97	Histone cluster 1 H1 family member c

0.79	GO:0006334	nucleosome assembly
0.58	GO:0098532	histone H3-K27 trimethylation
0.56	GO:0080182	histone H3-K4 trimethylation
0.55	GO:0016584	nucleosome positioning
0.55	GO:0000122	negative regulation of transcription by RNA polymerase II
0.47	GO:0071169	establishment of protein localization to chromatin
0.47	GO:0051574	positive regulation of histone H3-K9 methylation
0.45	GO:0030307	positive regulation of cell growth
0.44	GO:0050821	protein stabilization
0.43	GO:0048260	positive regulation of receptor-mediated endocytosis

0.66	GO:0031490	chromatin DNA binding
0.45	GO:0042826	histone deacetylase binding
0.42	GO:0008201	heparin binding
0.41	GO:0032564	dATP binding
0.38	GO:0016208	AMP binding
0.38	GO:0043531	ADP binding
0.37	GO:0003690	double-stranded DNA binding
0.37	GO:0005509	calcium ion binding
0.36	GO:0003723	RNA binding
0.36	GO:0032550	purine ribonucleoside binding

0.75	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.59	GO:0000791	euchromatin
0.55	GO:0031974	membrane-enclosed lumen
0.52	GO:0000792	heterochromatin
0.50	GO:0035327	transcriptionally active chromatin
0.41	GO:0031982	vesicle
0.40	GO:0009986	cell surface
0.37	GO:0043230	extracellular organelle
0.36	GO:0005615	extracellular space

sp|P02313|HMGN2_BOVIN
Non-histone chromosomal protein HMG-17
Search

HMGN2

0.94	High mobility group nucleosome-binding domain-containing protein 4

0.38	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.37	GO:0031640	killing of cells of other organism
0.36	GO:0040034	regulation of development, heterochronic
0.35	GO:0000122	negative regulation of transcription by RNA polymerase II
0.34	GO:0061098	positive regulation of protein tyrosine kinase activity
0.34	GO:0008154	actin polymerization or depolymerization
0.33	GO:0006334	nucleosome assembly
0.33	GO:0019538	protein metabolic process
0.33	GO:0043413	macromolecule glycosylation
0.33	GO:1901566	organonitrogen compound biosynthetic process

0.85	GO:0031492	nucleosomal DNA binding
0.35	GO:0030296	protein tyrosine kinase activator activity
0.34	GO:0004181	metallocarboxypeptidase activity
0.34	GO:0003723	RNA binding
0.33	GO:0005509	calcium ion binding
0.33	GO:0005515	protein binding
0.33	GO:0003735	structural constituent of ribosome
0.33	GO:0008270	zinc ion binding
0.33	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups

0.72	GO:0000785	chromatin
0.61	GO:0005634	nucleus
0.36	GO:0005615	extracellular space
0.35	GO:0005737	cytoplasm
0.33	GO:0030529	intracellular ribonucleoprotein complex

0.34

GO:0004181

sp|P02316|HMGN1_BOVIN
Non-histone chromosomal protein HMG-14
Search

HMGN1

0.93	Non-histone chromosomal protein HMG-14

0.43	GO:0048597	post-embryonic camera-type eye morphogenesis
0.43	GO:0000720	pyrimidine dimer repair by nucleotide-excision repair
0.43	GO:1901666	positive regulation of NAD+ ADP-ribosyltransferase activity
0.42	GO:0010225	response to UV-C
0.41	GO:0040034	regulation of development, heterochronic
0.41	GO:0010224	response to UV-B
0.40	GO:0050678	regulation of epithelial cell proliferation
0.40	GO:0006283	transcription-coupled nucleotide-excision repair
0.39	GO:0006325	chromatin organization
0.38	GO:0006357	regulation of transcription by RNA polymerase II

0.85	GO:0031492	nucleosomal DNA binding
0.34	GO:0005515	protein binding

0.72	GO:0000785	chromatin
0.61	GO:0005634	nucleus
0.35	GO:0031974	membrane-enclosed lumen
0.33	GO:0005737	cytoplasm

sp|P02318|HSP1_BOVIN
Sperm protamine P1
Search

PRM1

0.96	Protamine 1

0.80	GO:0007283	spermatogenesis
0.76	GO:0030261	chromosome condensation
0.72	GO:0030154	cell differentiation
0.68	GO:0007275	multicellular organism development
0.39	GO:0006997	nucleus organization
0.38	GO:0022412	cellular process involved in reproduction in multicellular organism
0.38	GO:0003006	developmental process involved in reproduction

0.55

GO:0003677

DNA binding

0.74	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.33	GO:0005737	cytoplasm

sp|P02453|CO1A1_BOVIN
Collagen alpha-1(I) chain
Search

COL1A1

0.82	Collagen type II alpha 1 chain

0.61	GO:0030199	collagen fibril organization
0.61	GO:0001958	endochondral ossification
0.61	GO:0060351	cartilage development involved in endochondral bone morphogenesis
0.59	GO:0048706	embryonic skeletal system development
0.59	GO:0007605	sensory perception of sound
0.57	GO:0032964	collagen biosynthetic process
0.57	GO:0007601	visual perception
0.57	GO:0034505	tooth mineralization
0.57	GO:0043589	skin morphogenesis
0.56	GO:0072359	circulatory system development

0.77	GO:0005201	extracellular matrix structural constituent
0.64	GO:0048407	platelet-derived growth factor binding
0.54	GO:0002020	protease binding
0.54	GO:0042802	identical protein binding
0.51	GO:0042289	MHC class II protein binding
0.37	GO:0046872	metal ion binding

0.73	GO:0005581	collagen trimer
0.63	GO:0098643	banded collagen fibril
0.55	GO:0005615	extracellular space
0.47	GO:0005604	basement membrane
0.40	GO:0005737	cytoplasm
0.38	GO:0097708	intracellular vesicle
0.38	GO:0012505	endomembrane system
0.35	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part

sp|P02459|CO2A1_BOVIN
Collagen alpha-1(II) chain
Search

COL2A1

0.86	Collagen type II alpha 1 chain

0.65	GO:0060272	embryonic skeletal joint morphogenesis
0.63	GO:0060174	limb bud formation
0.62	GO:0001502	cartilage condensation
0.62	GO:0030199	collagen fibril organization
0.62	GO:0071599	otic vesicle development
0.62	GO:0001958	endochondral ossification
0.62	GO:2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
0.62	GO:0060351	cartilage development involved in endochondral bone morphogenesis
0.62	GO:0030903	notochord development
0.61	GO:0002062	chondrocyte differentiation

0.80	GO:0005201	extracellular matrix structural constituent
0.65	GO:0048407	platelet-derived growth factor binding
0.64	GO:0042289	MHC class II protein binding
0.54	GO:0042802	identical protein binding
0.37	GO:0046872	metal ion binding

0.73	GO:0005581	collagen trimer
0.64	GO:0098643	banded collagen fibril
0.58	GO:0005604	basement membrane
0.55	GO:0005615	extracellular space
0.40	GO:0005737	cytoplasm
0.35	GO:0012505	endomembrane system
0.35	GO:0043233	organelle lumen
0.34	GO:0044446	intracellular organelle part
0.34	GO:0043231	intracellular membrane-bounded organelle

sp|P02465|CO1A2_BOVIN
Collagen alpha-2(I) chain
Search

COL1A2

0.90	Procollagen type I alpha 2 chain

0.57	GO:0043589	skin morphogenesis
0.56	GO:0070208	protein heterotrimerization
0.55	GO:0030199	collagen fibril organization
0.54	GO:0007266	Rho protein signal transduction
0.54	GO:0071230	cellular response to amino acid stimulus
0.53	GO:0007179	transforming growth factor beta receptor signaling pathway
0.53	GO:0008217	regulation of blood pressure
0.52	GO:0001501	skeletal system development
0.52	GO:0001568	blood vessel development
0.45	GO:0009612	response to mechanical stimulus

0.81	GO:0005201	extracellular matrix structural constituent
0.57	GO:0048407	platelet-derived growth factor binding
0.54	GO:0002020	protease binding
0.54	GO:0046332	SMAD binding
0.52	GO:0030674	protein binding, bridging
0.49	GO:0042802	identical protein binding
0.36	GO:0046872	metal ion binding

0.67	GO:0005581	collagen trimer
0.57	GO:0098643	banded collagen fibril
0.51	GO:0005615	extracellular space
0.48	GO:0005783	endoplasmic reticulum
0.35	GO:1903561	extracellular vesicle
0.33	GO:0070013	intracellular organelle lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|P02470|CRYAA_BOVIN
Alpha-crystallin A chain
Search

CRYAA

0.97	Alpha-crystallin A chain

0.53	GO:0070309	lens fiber cell morphogenesis
0.53	GO:0070141	response to UV-A
0.52	GO:0060561	apoptotic process involved in morphogenesis
0.52	GO:0048596	embryonic camera-type eye morphogenesis
0.51	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.50	GO:0007021	tubulin complex assembly
0.50	GO:0042542	response to hydrogen peroxide
0.50	GO:0030307	positive regulation of cell growth
0.50	GO:0001666	response to hypoxia
0.48	GO:0001934	positive regulation of protein phosphorylation

0.85	GO:0005212	structural constituent of eye lens
0.44	GO:0046872	metal ion binding
0.39	GO:0051082	unfolded protein binding
0.35	GO:0042802	identical protein binding

0.47	GO:0005634	nucleus
0.42	GO:0005737	cytoplasm
0.36	GO:0043233	organelle lumen
0.36	GO:0070062	extracellular exosome
0.35	GO:0044446	intracellular organelle part

sp|P02510|CRYAB_BOVIN
Alpha-crystallin B chain
Search

CRYAB

0.96	Alpha-crystallin B chain

0.62	GO:1905907	negative regulation of amyloid fibril formation
0.61	GO:0032463	negative regulation of protein homooligomerization
0.60	GO:0060561	apoptotic process involved in morphogenesis
0.59	GO:0071480	cellular response to gamma radiation
0.59	GO:0032387	negative regulation of intracellular transport
0.58	GO:0002088	lens development in camera-type eye
0.58	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.57	GO:0007021	tubulin complex assembly
0.57	GO:0042542	response to hydrogen peroxide
0.57	GO:0001666	response to hypoxia

0.83	GO:0005212	structural constituent of eye lens
0.58	GO:0001540	amyloid-beta binding
0.55	GO:0042803	protein homodimerization activity
0.53	GO:0032403	protein complex binding
0.51	GO:0051082	unfolded protein binding
0.39	GO:0008017	microtubule binding
0.38	GO:0046872	metal ion binding
0.36	GO:0008426	protein kinase C inhibitor activity
0.35	GO:0005080	protein kinase C binding
0.35	GO:0044183	protein binding involved in protein folding

0.58	GO:0030018	Z disc
0.57	GO:0043209	myelin sheath
0.50	GO:0005829	cytosol
0.47	GO:0005634	nucleus
0.46	GO:0005739	mitochondrion
0.43	GO:0005886	plasma membrane
0.42	GO:0097512	cardiac myofibril
0.41	GO:0031430	M band
0.41	GO:0043204	perikaryon
0.41	GO:0043197	dendritic spine

0.33

GO:0016757

sp|P02522|CRBB2_BOVIN
Beta-crystallin B2
Search

CRYBB2

0.97	Beta B2-crystallin short isoform

0.73	GO:0007601	visual perception
0.53	GO:0043010	camera-type eye development
0.34	GO:0006468	protein phosphorylation
0.34	GO:0050896	response to stimulus
0.33	GO:0023052	signaling
0.33	GO:0007154	cell communication
0.33	GO:0050789	regulation of biological process

0.80	GO:0005212	structural constituent of eye lens
0.51	GO:0042803	protein homodimerization activity
0.38	GO:0047696	beta-adrenergic receptor kinase activity
0.36	GO:0004703	G-protein coupled receptor kinase activity
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0097367	carbohydrate derivative binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.38

EC:2.7.11.15

GO:0047696

sp|P02526|CRGB_BOVIN
Gamma-crystallin B
Search

0.97	Gamma-crystallin B

0.77	GO:0002088	lens development in camera-type eye
0.63	GO:0030855	epithelial cell differentiation
0.60	GO:0007601	visual perception
0.59	GO:0048593	camera-type eye morphogenesis
0.56	GO:0000904	cell morphogenesis involved in differentiation
0.50	GO:0034614	cellular response to reactive oxygen species
0.41	GO:0043434	response to peptide hormone
0.36	GO:0006102	isocitrate metabolic process
0.33	GO:0055114	oxidation-reduction process

0.76	GO:0005212	structural constituent of eye lens
0.36	GO:0004450	isocitrate dehydrogenase (NADP+) activity
0.35	GO:0005515	protein binding
0.34	GO:0051287	NAD binding
0.34	GO:0000287	magnesium ion binding

0.54	GO:0005634	nucleus
0.45	GO:0005737	cytoplasm

0.36

GO:0004450

sp|P02527|CRGA_BOVIN
Gamma-crystallin A
Search

0.96	Gamma-crystallin A

0.78	GO:0002088	lens development in camera-type eye
0.62	GO:0030855	epithelial cell differentiation
0.61	GO:0048593	camera-type eye morphogenesis
0.58	GO:0007601	visual perception
0.58	GO:0000904	cell morphogenesis involved in differentiation
0.47	GO:0034614	cellular response to reactive oxygen species
0.39	GO:0043434	response to peptide hormone
0.36	GO:0006102	isocitrate metabolic process
0.33	GO:0055114	oxidation-reduction process

0.76	GO:0005212	structural constituent of eye lens
0.36	GO:0004450	isocitrate dehydrogenase (NADP+) activity
0.35	GO:0051287	NAD binding
0.34	GO:0000287	magnesium ion binding
0.34	GO:0005515	protein binding

0.54	GO:0005634	nucleus
0.44	GO:0005737	cytoplasm

0.36

GO:0004450

sp|P02548|NFL_BOVIN
Neurofilament light polypeptide
Search

NEFL

0.97	Neurofilament light polypeptide

0.75	GO:0061564	axon development
0.63	GO:0033693	neurofilament bundle assembly
0.61	GO:0019896	axonal transport of mitochondrion
0.60	GO:0008090	retrograde axonal transport
0.59	GO:0008089	anterograde axonal transport
0.58	GO:0031133	regulation of axon diameter
0.56	GO:0031102	neuron projection regeneration
0.56	GO:0048678	response to axon injury
0.55	GO:0050885	neuromuscular process controlling balance
0.55	GO:0050772	positive regulation of axonogenesis

0.62	GO:0005198	structural molecule activity
0.57	GO:0008022	protein C-terminus binding
0.53	GO:0030674	protein binding, bridging
0.52	GO:0042802	identical protein binding
0.40	GO:0043274	phospholipase binding
0.38	GO:0019904	protein domain specific binding
0.37	GO:0046982	protein heterodimerization activity
0.35	GO:0019901	protein kinase binding
0.35	GO:0005088	Ras guanyl-nucleotide exchange factor activity

0.85	GO:0005883	neurofilament
0.59	GO:0033596	TSC1-TSC2 complex
0.58	GO:1904115	axon cytoplasm
0.54	GO:0043209	myelin sheath
0.39	GO:0030426	growth cone
0.36	GO:0097418	neurofibrillary tangle
0.36	GO:0031965	nuclear membrane
0.36	GO:0036464	cytoplasmic ribonucleoprotein granule
0.35	GO:0045098	type III intermediate filament
0.35	GO:0005654	nucleoplasm

sp|P02584|PROF1_BOVIN
Profilin-1
Search

PFN1

0.69

Profilin

0.73	GO:0030036	actin cytoskeleton organization
0.68	GO:0030833	regulation of actin filament polymerization
0.56	GO:0032231	regulation of actin filament bundle assembly
0.55	GO:1900027	regulation of ruffle assembly
0.53	GO:0110020	regulation of actomyosin structure organization
0.53	GO:1902905	positive regulation of supramolecular fiber organization
0.53	GO:0051495	positive regulation of cytoskeleton organization
0.53	GO:0010632	regulation of epithelial cell migration
0.53	GO:0044089	positive regulation of cellular component biogenesis
0.52	GO:0032272	negative regulation of protein polymerization

0.74	GO:0003779	actin binding
0.53	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.51	GO:0070064	proline-rich region binding
0.48	GO:0045296	cadherin binding
0.47	GO:0000774	adenyl-nucleotide exchange factor activity
0.46	GO:0017048	Rho GTPase binding
0.38	GO:0016887	ATPase activity
0.37	GO:0005102	receptor binding
0.34	GO:0003723	RNA binding

0.46	GO:0005938	cell cortex
0.46	GO:0005615	extracellular space
0.45	GO:0043195	terminal bouton
0.42	GO:0005634	nucleus
0.38	GO:1903561	extracellular vesicle
0.38	GO:0005856	cytoskeleton
0.37	GO:0005925	focal adhesion
0.35	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.38

GO:0016887

sp|P02633|S100G_BOVIN
Protein S100-G
Search

0.56	Calcium-binding protein, intestinal, major form

0.41	GO:0042127	regulation of cell proliferation
0.33	GO:0006468	protein phosphorylation

0.70	GO:0005509	calcium ion binding
0.54	GO:0046914	transition metal ion binding
0.51	GO:0005499	vitamin D binding
0.44	GO:0048306	calcium-dependent protein binding
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0097367	carbohydrate derivative binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0004672	protein kinase activity

0.62	GO:0016323	basolateral plasma membrane
0.61	GO:0016324	apical plasma membrane
0.33	GO:0005634	nucleus
0.32	GO:0005737	cytoplasm

sp|P02638|S100B_BOVIN
Protein S100-B
Search

S100B

0.40	S100 calcium binding protein B

0.53	GO:0048168	regulation of neuronal synaptic plasticity
0.53	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.52	GO:0007613	memory
0.49	GO:0050727	regulation of inflammatory response
0.48	GO:0045087	innate immune response
0.42	GO:0048708	astrocyte differentiation
0.42	GO:0031643	positive regulation of myelination
0.42	GO:0051597	response to methylmercury
0.42	GO:2001015	negative regulation of skeletal muscle cell differentiation
0.41	GO:0060291	long-term synaptic potentiation

0.70	GO:0005509	calcium ion binding
0.63	GO:0050786	RAGE receptor binding
0.63	GO:0008270	zinc ion binding
0.56	GO:0044548	S100 protein binding
0.55	GO:0048306	calcium-dependent protein binding
0.52	GO:0035662	Toll-like receptor 4 binding
0.52	GO:0050544	arachidonic acid binding
0.51	GO:0042803	protein homodimerization activity
0.48	GO:0008092	cytoskeletal protein binding
0.35	GO:0019210	kinase inhibitor activity

0.54	GO:0001726	ruffle
0.52	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0043025	neuronal cell body
0.45	GO:0005634	nucleus
0.40	GO:0005576	extracellular region
0.39	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.37	GO:0005829	cytosol
0.37	GO:0012505	endomembrane system
0.36	GO:0045178	basal part of cell
0.36	GO:0031967	organelle envelope

sp|P02639|S10A1_BOVIN
Protein S100-A1
Search

sp|P02662|CASA1_BOVIN
Alpha-S1-casein
Search

CSN1S1

0.93	Alpha-S1-casein

0.55	GO:1903456	positive regulation of androst-4-ene-3,17-dione biosynthetic process
0.55	GO:2000837	regulation of androstenedione secretion
0.54	GO:2000184	positive regulation of progesterone biosynthetic process
0.53	GO:2000872	positive regulation of progesterone secretion
0.53	GO:1903496	response to 11-deoxycorticosterone
0.53	GO:1903494	response to dehydroepiandrosterone
0.50	GO:0032570	response to progesterone
0.50	GO:0060416	response to growth hormone
0.50	GO:0032355	response to estradiol
0.47	GO:0043066	negative regulation of apoptotic process

0.44	GO:0001540	amyloid-beta binding
0.40	GO:0016209	antioxidant activity

0.66	GO:0005576	extracellular region
0.51	GO:0005796	Golgi lumen
0.30	GO:0031224	intrinsic component of membrane

sp|P02663|CASA2_BOVIN
Alpha-S2-casein
Search

CSN1S2

0.97	Alpha-S2-casein variant A

0.44	GO:1903494	response to dehydroepiandrosterone
0.44	GO:1903496	response to 11-deoxycorticosterone
0.42	GO:0032570	response to progesterone
0.42	GO:0060416	response to growth hormone
0.42	GO:0032355	response to estradiol
0.40	GO:0042742	defense response to bacterium

0.51	GO:0035375	zymogen binding
0.45	GO:0042803	protein homodimerization activity

0.66	GO:0005576	extracellular region
0.43	GO:0005796	Golgi lumen

sp|P02666|CASB_BOVIN
Beta-casein
Search

CSN2

0.97	Beta-casein

0.53	GO:0007595	lactation
0.51	GO:2000117	negative regulation of cysteine-type endopeptidase activity
0.47	GO:1903488	negative regulation of lactation
0.42	GO:0006816	calcium ion transport
0.38	GO:1903720	negative regulation of I-kappaB phosphorylation
0.38	GO:1903494	response to dehydroepiandrosterone
0.38	GO:1903496	response to 11-deoxycorticosterone
0.37	GO:0009408	response to heat
0.37	GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway
0.37	GO:0032570	response to progesterone

0.50	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.40	GO:0005509	calcium ion binding
0.37	GO:0042803	protein homodimerization activity
0.37	GO:0019870	potassium channel inhibitor activity
0.37	GO:0008191	metalloendopeptidase inhibitor activity
0.35	GO:0016209	antioxidant activity

0.65	GO:0005576	extracellular region
0.37	GO:0005796	Golgi lumen

sp|P02668|CASK_BOVIN
Kappa-casein
Search

CSN3

0.91	Kappa-casein

0.49	GO:1903496	response to 11-deoxycorticosterone
0.49	GO:1903494	response to dehydroepiandrosterone
0.47	GO:0032570	response to progesterone
0.47	GO:0032355	response to estradiol
0.44	GO:0051260	protein homooligomerization
0.40	GO:0007595	lactation
0.39	GO:0050821	protein stabilization

0.49	GO:0035375	zymogen binding
0.34	GO:0042802	identical protein binding

0.66	GO:0005576	extracellular region
0.47	GO:0005796	Golgi lumen
0.30	GO:0031224	intrinsic component of membrane

sp|P02672|FIBA_BOVIN
Fibrinogen alpha chain
Search

FGA

0.80	Fibrinogen alpha chain

0.83	GO:0030168	platelet activation
0.75	GO:0051258	protein polymerization
0.62	GO:0072377	blood coagulation, common pathway
0.60	GO:0043152	induction of bacterial agglutination
0.59	GO:0007165	signal transduction
0.59	GO:0034116	positive regulation of heterotypic cell-cell adhesion
0.59	GO:0042730	fibrinolysis
0.58	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.58	GO:0045907	positive regulation of vasoconstriction
0.58	GO:2000352	negative regulation of endothelial cell apoptotic process

0.78	GO:0030674	protein binding, bridging
0.71	GO:0005102	receptor binding
0.54	GO:0050839	cell adhesion molecule binding
0.45	GO:0005198	structural molecule activity
0.34	GO:0046872	metal ion binding

0.85	GO:0005577	fibrinogen complex
0.58	GO:0031091	platelet alpha granule
0.55	GO:0009897	external side of plasma membrane
0.52	GO:0005938	cell cortex
0.38	GO:0034774	secretory granule lumen
0.38	GO:0072562	blood microparticle
0.37	GO:0005788	endoplasmic reticulum lumen
0.37	GO:0070062	extracellular exosome
0.32	GO:0005791	rough endoplasmic reticulum
0.30	GO:0016021	integral component of membrane

sp|P02676|FIBB_BOVIN
Fibrinogen beta chain
Search

FGB

0.72	Fibrinogen beta chain

0.82	GO:0030168	platelet activation
0.75	GO:0051258	protein polymerization
0.62	GO:0072378	blood coagulation, fibrin clot formation
0.62	GO:0043152	induction of bacterial agglutination
0.61	GO:0034116	positive regulation of heterotypic cell-cell adhesion
0.61	GO:0042730	fibrinolysis
0.60	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.60	GO:0045907	positive regulation of vasoconstriction
0.60	GO:2000352	negative regulation of endothelial cell apoptotic process
0.60	GO:0031639	plasminogen activation

0.78	GO:0030674	protein binding, bridging
0.71	GO:0005102	receptor binding
0.56	GO:0050839	cell adhesion molecule binding
0.54	GO:0051087	chaperone binding
0.46	GO:0005198	structural molecule activity
0.32	GO:0046872	metal ion binding

0.85	GO:0005577	fibrinogen complex
0.60	GO:0031091	platelet alpha granule
0.56	GO:0009897	external side of plasma membrane
0.54	GO:0005938	cell cortex
0.51	GO:0005783	endoplasmic reticulum
0.41	GO:0072562	blood microparticle
0.36	GO:0070062	extracellular exosome
0.35	GO:0034774	secretory granule lumen

sp|P02687|MBP_BOVIN
Myelin basic protein
Search

MBP

0.96	myelin basic protein isoform X4

0.54	GO:0042552	myelination
0.50	GO:0007605	sensory perception of sound
0.44	GO:0007417	central nervous system development
0.44	GO:0009636	response to toxic substance
0.44	GO:0061024	membrane organization
0.41	GO:1904207	regulation of chemokine (C-C motif) ligand 2 secretion
0.40	GO:0035633	maintenance of permeability of blood-brain barrier
0.40	GO:1904685	positive regulation of metalloendopeptidase activity
0.40	GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production
0.40	GO:0034115	negative regulation of heterotypic cell-cell adhesion

0.86	GO:0019911	structural constituent of myelin sheath
0.51	GO:0002020	protease binding
0.50	GO:0005516	calmodulin binding
0.35	GO:0005543	phospholipid binding

0.58	GO:0033269	internode region of axon
0.55	GO:0043209	myelin sheath
0.53	GO:0043025	neuronal cell body
0.42	GO:0043234	protein complex
0.42	GO:0071944	cell periphery
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|P02690|MYP2_BOVIN
Myelin P2 protein
Search

PMP2

0.93	Fatty acid-binding protein, adipocyte

0.57	GO:0061024	membrane organization
0.56	GO:0050727	regulation of inflammatory response
0.50	GO:0050872	white fat cell differentiation
0.49	GO:0071285	cellular response to lithium ion
0.49	GO:0050873	brown fat cell differentiation
0.48	GO:0042632	cholesterol homeostasis
0.48	GO:0001816	cytokine production
0.47	GO:0071356	cellular response to tumor necrosis factor
0.46	GO:0032103	positive regulation of response to external stimulus
0.46	GO:0006469	negative regulation of protein kinase activity

0.72	GO:0008289	lipid binding
0.59	GO:0033293	monocarboxylic acid binding
0.54	GO:0043178	alcohol binding
0.37	GO:0097159	organic cyclic compound binding
0.34	GO:0005515	protein binding

0.68	GO:0043209	myelin sheath
0.37	GO:0031982	vesicle
0.37	GO:0043230	extracellular organelle
0.36	GO:0005829	cytosol
0.36	GO:0005615	extracellular space
0.35	GO:0097223	sperm part
0.35	GO:0005634	nucleus
0.35	GO:0043025	neuronal cell body
0.35	GO:0005911	cell-cell junction
0.34	GO:0042995	cell projection

sp|P02694|RET1_BOVIN
Retinol-binding protein 1
Search

RBP1

0.97	Nicotinamide nucleotide adenylyltransferase 3

0.84	GO:0006776	vitamin A metabolic process
0.83	GO:0002138	retinoic acid biosynthetic process
0.55	GO:0033189	response to vitamin A
0.54	GO:0030852	regulation of granulocyte differentiation
0.53	GO:0042572	retinol metabolic process
0.38	GO:0055088	lipid homeostasis
0.35	GO:0009435	NAD biosynthetic process
0.34	GO:0009611	response to wounding
0.32	GO:0016310	phosphorylation

0.72	GO:0008289	lipid binding
0.41	GO:0019842	vitamin binding
0.41	GO:0043178	alcohol binding
0.38	GO:0016779	nucleotidyltransferase activity
0.32	GO:0005515	protein binding
0.32	GO:0016301	kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.64	GO:0005829	cytosol
0.51	GO:0005811	lipid droplet
0.47	GO:0005654	nucleoplasm
0.38	GO:0044297	cell body
0.34	GO:0070062	extracellular exosome
0.32	GO:0005739	mitochondrion

0.38

EC:2.7.7

GO:0016779

sp|P02698|GBG1_BOVIN
Guanine nucleotide-binding protein G(T) subunit gamma-T1
Search

0.71	Guanine nucleotide-binding protein subunit gamma

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.52	GO:0042462	eye photoreceptor cell development
0.50	GO:0007602	phototransduction
0.44	GO:0008104	protein localization
0.40	GO:0010659	cardiac muscle cell apoptotic process
0.38	GO:0071456	cellular response to hypoxia
0.35	GO:0022400	regulation of rhodopsin mediated signaling pathway
0.35	GO:0071377	cellular response to glucagon stimulus
0.35	GO:0071482	cellular response to light stimulus
0.35	GO:0009584	detection of visible light

0.64	GO:0004871	signal transducer activity
0.41	GO:0003924	GTPase activity
0.34	GO:0005515	protein binding
0.34	GO:0003995	acyl-CoA dehydrogenase activity
0.33	GO:0050660	flavin adenine dinucleotide binding

0.81	GO:1905360	GTPase complex
0.79	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.65	GO:0098797	plasma membrane protein complex
0.39	GO:0001750	photoreceptor outer segment
0.38	GO:0001917	photoreceptor inner segment
0.37	GO:0060170	ciliary membrane

0.34

EC:1.3.99.3

GO:0003995

sp|P02699|OPSD_BOVIN
Rhodopsin
Search

RHO

0.57

Rhodopsin

0.79	GO:0007602	phototransduction
0.75	GO:0007601	visual perception
0.72	GO:0018298	protein-chromophore linkage
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.65	GO:0016037	light absorption
0.59	GO:0071482	cellular response to light stimulus
0.57	GO:0045494	photoreceptor cell maintenance
0.55	GO:0060041	retina development in camera-type eye
0.51	GO:0009584	detection of visible light
0.46	GO:0006468	protein phosphorylation

0.76	GO:0009881	photoreceptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.53	GO:0005502	11-cis retinal binding
0.40	GO:0042802	identical protein binding
0.39	GO:0046872	metal ion binding
0.38	GO:0046983	protein dimerization activity
0.37	GO:0030507	spectrin binding
0.36	GO:0002046	opsin binding
0.36	GO:1990763	arrestin family protein binding
0.35	GO:0001965	G-protein alpha-subunit binding

0.66	GO:0060342	photoreceptor inner segment membrane
0.65	GO:0097381	photoreceptor disc membrane
0.64	GO:0042622	photoreceptor outer segment membrane
0.52	GO:0005911	cell-cell junction
0.50	GO:0005794	Golgi apparatus
0.36	GO:0031984	organelle subcompartment
0.35	GO:0097648	G-protein coupled receptor complex
0.35	GO:0005791	rough endoplasmic reticulum
0.34	GO:0030660	Golgi-associated vesicle membrane
0.34	GO:0000786	nucleosome

sp|P02702|FOLR1_BOVIN
Folate receptor alpha
Search

0.72	Folate receptor alpha

0.85	GO:0015884	folic acid transport
0.61	GO:0071231	cellular response to folic acid
0.54	GO:0061713	anterior neural tube closure
0.53	GO:0003147	neural crest cell migration involved in heart formation
0.53	GO:0003253	cardiac neural crest cell migration involved in outflow tract morphogenesis
0.52	GO:0061626	pharyngeal arch artery morphogenesis
0.51	GO:0031103	axon regeneration
0.50	GO:0001947	heart looping
0.49	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway
0.48	GO:0060828	regulation of canonical Wnt signaling pathway

0.85	GO:0008517	folic acid transmembrane transporter activity
0.82	GO:0005542	folic acid binding
0.61	GO:0061714	folic acid receptor activity
0.60	GO:0051870	methotrexate binding
0.33	GO:0008270	zinc ion binding

0.58	GO:0031362	anchored component of external side of plasma membrane
0.49	GO:0016324	apical plasma membrane
0.49	GO:0016323	basolateral plasma membrane
0.41	GO:0031526	brush border membrane
0.41	GO:0005634	nucleus
0.40	GO:0031982	vesicle
0.39	GO:0005576	extracellular region
0.37	GO:0012505	endomembrane system
0.35	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane
0.34	GO:0019898	extrinsic component of membrane

sp|P02709|ACHA_BOVIN
Acetylcholine receptor subunit alpha
Search

CHRNA1

0.94	Nicotinic acetylcholine recepter alpha-subunit

0.79	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.47	GO:0007274	neuromuscular synaptic transmission
0.47	GO:0048630	skeletal muscle tissue growth
0.46	GO:0035094	response to nicotine
0.46	GO:0007271	synaptic transmission, cholinergic
0.46	GO:0070050	neuron cellular homeostasis
0.46	GO:0003009	skeletal muscle contraction
0.45	GO:0019228	neuronal action potential
0.45	GO:0046716	muscle cell cellular homeostasis

0.82	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0004888	transmembrane signaling receptor activity
0.48	GO:0042166	acetylcholine binding
0.36	GO:0005515	protein binding

0.78	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.47	GO:0005892	acetylcholine-gated channel complex
0.45	GO:0031594	neuromuscular junction
0.42	GO:0009986	cell surface

sp|P02715|ACHE_BOVIN
Acetylcholine receptor subunit epsilon
Search

CHRNE

0.90	Cholinergic receptor nicotinic epsilon subunit

0.80	GO:0060079	excitatory postsynaptic potential
0.63	GO:0007271	synaptic transmission, cholinergic
0.60	GO:0034220	ion transmembrane transport
0.55	GO:0035094	response to nicotine
0.54	GO:0007274	neuromuscular synaptic transmission
0.43	GO:0006812	cation transport

0.83	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0099600	transmembrane receptor activity
0.56	GO:0042166	acetylcholine binding

0.79	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.63	GO:0005892	acetylcholine-gated channel complex

sp|P02720|PPCT_BOVIN
Phosphatidylcholine transfer protein
Search

PCTP

0.97	phosphatidylcholine transfer protein isoform X1

0.48	GO:0015914	phospholipid transport
0.37	GO:0008203	cholesterol metabolic process
0.35	GO:0006656	phosphatidylcholine biosynthetic process
0.33	GO:0043933	macromolecular complex subunit organization
0.33	GO:0022411	cellular component disassembly
0.33	GO:0031497	chromatin assembly
0.32	GO:0006518	peptide metabolic process
0.32	GO:0043604	amide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0010467	gene expression

0.72	GO:0008289	lipid binding
0.53	GO:0008525	phosphatidylcholine transporter activity
0.52	GO:0050997	quaternary ammonium group binding
0.49	GO:0070405	ammonium ion binding
0.38	GO:0043168	anion binding
0.33	GO:0005515	protein binding
0.33	GO:0008079	translation termination factor activity

0.44	GO:0005829	cytosol
0.32	GO:0005634	nucleus

sp|P02721|ATP5J_BOVIN
ATP synthase-coupling factor 6, mitochondrial
Search

ATP5J

0.95	ATP synthase-coupling factor 6, mitochondrial

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.38	GO:0021762	substantia nigra development
0.35	GO:0042407	cristae formation
0.35	GO:0046907	intracellular transport
0.35	GO:1904263	positive regulation of TORC1 signaling
0.35	GO:0006839	mitochondrial transport
0.35	GO:0048194	Golgi vesicle budding
0.33	GO:0015031	protein transport

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.43	GO:0016887	ATPase activity
0.36	GO:0047624	adenosine-tetraphosphatase activity
0.33	GO:0005198	structural molecule activity
0.32	GO:1901265	nucleoside phosphate binding
0.32	GO:0036094	small molecule binding

0.78	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
0.34	GO:0030127	COPII vesicle coat
0.34	GO:0000139	Golgi membrane
0.33	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.43

GO:0016887

sp|P02722|ADT1_BOVIN
ADP/ATP translocase 1
Search

SLC25A4

0.90	Solute carrier family 25 (Mitochondrial carrier adenine nucleotide translocator), member 4

0.57	GO:0015866	ADP transport
0.55	GO:0046902	regulation of mitochondrial membrane permeability
0.55	GO:0055085	transmembrane transport
0.53	GO:0060546	negative regulation of necroptotic process
0.52	GO:0008637	apoptotic mitochondrial changes
0.51	GO:0015867	ATP transport
0.47	GO:0010823	negative regulation of mitochondrion organization
0.46	GO:2001234	negative regulation of apoptotic signaling pathway
0.45	GO:0051051	negative regulation of transport
0.45	GO:0008284	positive regulation of cell proliferation

0.57	GO:0022857	transmembrane transporter activity
0.43	GO:0031625	ubiquitin protein ligase binding
0.33	GO:0003723	RNA binding

0.62	GO:0005743	mitochondrial inner membrane
0.54	GO:0043209	myelin sheath
0.48	GO:0071817	MMXD complex
0.44	GO:0042645	mitochondrial nucleoid
0.39	GO:0032592	integral component of mitochondrial membrane
0.36	GO:0098805	whole membrane
0.35	GO:0031012	extracellular matrix
0.35	GO:0098588	bounding membrane of organelle
0.34	GO:0005634	nucleus
0.34	GO:0019867	outer membrane

sp|P02754|LACB_BOVIN
Beta-lactoglobulin
Search

0.95	Major allergen beta-lactoglobulin

0.39	GO:1902491	negative regulation of sperm capacitation
0.39	GO:2000359	regulation of binding of sperm to zona pellucida
0.38	GO:2000667	positive regulation of interleukin-13 secretion
0.38	GO:0032725	positive regulation of granulocyte macrophage colony-stimulating factor production
0.38	GO:2000778	positive regulation of interleukin-6 secretion
0.36	GO:0006915	apoptotic process

0.63	GO:0019841	retinol binding
0.40	GO:0042802	identical protein binding
0.40	GO:0036041	long-chain fatty acid binding

0.50

GO:0005576

extracellular region

sp|P02769|ALBU_BOVIN
Serum albumin
Search

ALB

0.94	serum albumin precursor

0.62	GO:0051659	maintenance of mitochondrion location
0.58	GO:0019836	hemolysis by symbiont of host erythrocytes
0.54	GO:0009267	cellular response to starvation
0.54	GO:0043066	negative regulation of apoptotic process
0.38	GO:0001542	ovulation from ovarian follicle
0.38	GO:0042448	progesterone metabolic process
0.37	GO:0001895	retina homeostasis
0.37	GO:0060395	SMAD protein signal transduction
0.36	GO:0070541	response to platinum ion
0.36	GO:0007584	response to nutrient

0.58	GO:0005504	fatty acid binding
0.56	GO:0015643	toxic substance binding
0.54	GO:0019825	oxygen binding
0.50	GO:0051087	chaperone binding
0.48	GO:0042802	identical protein binding
0.48	GO:0030170	pyridoxal phosphate binding
0.42	GO:0003677	DNA binding
0.39	GO:0046872	metal ion binding
0.35	GO:0008431	vitamin E binding
0.34	GO:0004817	cysteine-tRNA ligase activity

0.73	GO:0005615	extracellular space
0.52	GO:0043209	myelin sheath
0.51	GO:1903561	extracellular vesicle
0.49	GO:0005794	Golgi apparatus
0.48	GO:0005783	endoplasmic reticulum
0.45	GO:0043234	protein complex
0.36	GO:0031093	platelet alpha granule lumen
0.35	GO:0060417	yolk
0.35	GO:0005604	basement membrane
0.34	GO:0005634	nucleus

0.34

EC:6.1.1.16

GO:0004817

sp|P02777|PLF4_BOVIN
Platelet factor 4
Search

PF4

0.87	Platelet factor 4

0.85	GO:0045653	negative regulation of megakaryocyte differentiation
0.84	GO:0030168	platelet activation
0.84	GO:0030595	leukocyte chemotaxis
0.83	GO:0043950	positive regulation of cAMP-mediated signaling
0.81	GO:0030816	positive regulation of cAMP metabolic process
0.78	GO:0016525	negative regulation of angiogenesis
0.75	GO:0090023	positive regulation of neutrophil chemotaxis
0.74	GO:0006955	immune response
0.74	GO:0019221	cytokine-mediated signaling pathway
0.71	GO:0042127	regulation of cell proliferation

0.85	GO:0048248	CXCR3 chemokine receptor binding
0.84	GO:0008009	chemokine activity
0.83	GO:0008201	heparin binding

0.68	GO:0005615	extracellular space
0.54	GO:0097679	other organism cytoplasm
0.54	GO:0020005	symbiont-containing vacuole membrane
0.37	GO:0005737	cytoplasm

sp|P02784|SFP1_BOVIN
Seminal plasma protein PDC-109
Search

0.95	Seminal plasma protein HSP-1

0.72	GO:0048240	sperm capacitation
0.51	GO:0007041	lysosomal transport
0.50	GO:0007338	single fertilization
0.47	GO:1902492	positive regulation of sperm capacitation
0.46	GO:0030574	collagen catabolic process
0.45	GO:0016477	cell migration
0.45	GO:0033700	phospholipid efflux
0.44	GO:0001503	ossification
0.42	GO:0048732	gland development
0.41	GO:0003128	heart field specification

0.64	GO:0008201	heparin binding
0.50	GO:0051219	phosphoprotein binding
0.43	GO:0004872	receptor activity
0.43	GO:0005537	mannose binding
0.42	GO:0005520	insulin-like growth factor binding
0.41	GO:0004222	metalloendopeptidase activity
0.41	GO:0001972	retinoic acid binding
0.40	GO:0001965	G-protein alpha-subunit binding
0.40	GO:0042802	identical protein binding
0.39	GO:0008270	zinc ion binding

0.60	GO:0009986	cell surface
0.58	GO:0005576	extracellular region
0.43	GO:0005641	nuclear envelope lumen
0.42	GO:0030140	trans-Golgi network transport vesicle
0.42	GO:0030139	endocytic vesicle
0.42	GO:0005770	late endosome
0.42	GO:0005769	early endosome
0.41	GO:0005802	trans-Golgi network
0.39	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0030118	clathrin coat

0.41

GO:0004222

sp|P02817|AMELX_BOVIN
Amelogenin, X isoform
Search

AMELX

0.87	Y-linked amelogenin

0.70	GO:0007275	multicellular organism development
0.48	GO:0009888	tissue development
0.46	GO:0009653	anatomical structure morphogenesis
0.38	GO:0010714	positive regulation of collagen metabolic process
0.38	GO:0032965	regulation of collagen biosynthetic process
0.37	GO:0001649	osteoblast differentiation
0.37	GO:0051260	protein homooligomerization
0.37	GO:0042127	regulation of cell proliferation
0.37	GO:0051592	response to calcium ion
0.37	GO:0010469	regulation of receptor activity

0.54	GO:0030345	structural constituent of tooth enamel
0.40	GO:0046848	hydroxyapatite binding
0.38	GO:0042802	identical protein binding
0.37	GO:0008083	growth factor activity
0.36	GO:0031402	sodium ion binding
0.36	GO:0005509	calcium ion binding
0.35	GO:0046983	protein dimerization activity

0.76	GO:0005578	proteinaceous extracellular matrix
0.37	GO:0009986	cell surface
0.36	GO:0030139	endocytic vesicle
0.36	GO:0044420	extracellular matrix component
0.36	GO:0099080	supramolecular complex
0.36	GO:0012505	endomembrane system
0.34	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0043234	protein complex
0.33	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part

sp|P02820|OSTCN_BOVIN
Osteocalcin
Search

BGLAP

0.97	Osteocalcin

0.85	GO:0030500	regulation of bone mineralization
0.66	GO:0033280	response to vitamin D
0.63	GO:0001649	osteoblast differentiation
0.62	GO:0031214	biomineral tissue development
0.42	GO:0033594	response to hydroxyisoflavone
0.41	GO:0032571	response to vitamin K
0.41	GO:0033574	response to testosterone
0.41	GO:0071295	cellular response to vitamin
0.40	GO:0014823	response to activity
0.40	GO:0009629	response to gravity

0.70	GO:0005509	calcium ion binding
0.43	GO:0008147	structural constituent of bone
0.39	GO:0046848	hydroxyapatite binding
0.35	GO:0042803	protein homodimerization activity
0.33	GO:0046914	transition metal ion binding

0.66	GO:0005576	extracellular region
0.44	GO:0005737	cytoplasm
0.40	GO:0043204	perikaryon
0.39	GO:0030425	dendrite
0.38	GO:0031982	vesicle
0.37	GO:0012505	endomembrane system
0.35	GO:0070013	intracellular organelle lumen
0.35	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0044446	intracellular organelle part

sp|P03887|NU1M_BOVIN
NADH-ubiquinone oxidoreductase chain 1
Search

ND1

0.44	NADH-ubiquinone oxidoreductase chain 1

0.53	GO:0055114	oxidation-reduction process
0.33	GO:0006091	generation of precursor metabolites and energy

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.38	GO:0045271	respiratory chain complex I
0.37	GO:0098798	mitochondrial protein complex
0.36	GO:1990204	oxidoreductase complex
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0008137

sp|P03892|NU2M_BOVIN
NADH-ubiquinone oxidoreductase chain 2
Search

ND2

0.44	NADH-ubiquinone oxidoreductase chain 2

0.75	GO:0006120	mitochondrial electron transport, NADH to ubiquinone
0.35	GO:0072593	reactive oxygen species metabolic process

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.62	GO:0070469	respiratory chain
0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.37	GO:0030964	NADH dehydrogenase complex
0.36	GO:0098798	mitochondrial protein complex
0.35	GO:1990204	oxidoreductase complex
0.34	GO:0098796	membrane protein complex
0.30	GO:0016021	integral component of membrane

0.69

GO:0008137

sp|P03898|NU3M_BOVIN
NADH-ubiquinone oxidoreductase chain 3
Search

ND3

0.46	NADH-ubiquinone oxidoreductase chain 3

0.53

GO:0055114

oxidation-reduction process

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.62	GO:0070469	respiratory chain
0.61	GO:0031966	mitochondrial membrane
0.38	GO:0030964	NADH dehydrogenase complex
0.37	GO:0098798	mitochondrial protein complex
0.36	GO:1990204	oxidoreductase complex
0.35	GO:0098796	membrane protein complex
0.35	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0008137

sp|P03902|NU4LM_BOVIN
NADH-ubiquinone oxidoreductase chain 4L
Search

ND4L

0.50	NADH-ubiquinone oxidoreductase chain 4L

0.69

GO:0042773

ATP synthesis coupled electron transport

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.61	GO:0005739	mitochondrion
0.39	GO:0070469	respiratory chain
0.38	GO:0031967	organelle envelope
0.38	GO:0031090	organelle membrane
0.36	GO:0030964	NADH dehydrogenase complex
0.34	GO:1990204	oxidoreductase complex
0.34	GO:0098796	membrane protein complex
0.30	GO:0016021	integral component of membrane

0.69

GO:0008137

sp|P03910|NU4M_BOVIN
NADH-ubiquinone oxidoreductase chain 4
Search

ND4

0.48	NADH-ubiquinone oxidoreductase chain 4

0.75

GO:0006120

mitochondrial electron transport, NADH to ubiquinone

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.61	GO:0005739	mitochondrion
0.36	GO:0045271	respiratory chain complex I
0.35	GO:0031967	organelle envelope
0.35	GO:0031090	organelle membrane
0.34	GO:1990204	oxidoreductase complex
0.30	GO:0016021	integral component of membrane

0.69

GO:0008137

sp|P03920|NU5M_BOVIN
NADH-ubiquinone oxidoreductase chain 5
Search

ND5

0.46	NADH-ubiquinone oxidoreductase chain 5

0.69

GO:0042773

ATP synthesis coupled electron transport

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.62	GO:0070469	respiratory chain
0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.36	GO:0030964	NADH dehydrogenase complex
0.35	GO:0098798	mitochondrial protein complex
0.35	GO:1990204	oxidoreductase complex
0.34	GO:0098796	membrane protein complex
0.30	GO:0016021	integral component of membrane

0.69

GO:0008137

sp|P03924|NU6M_BOVIN
NADH-ubiquinone oxidoreductase chain 6
Search

ND6

0.50	NADH-ubiquinone oxidoreductase chain 6

0.53

GO:0055114

oxidation-reduction process

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.61	GO:0005739	mitochondrion
0.34	GO:0070469	respiratory chain
0.34	GO:0031967	organelle envelope
0.34	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0008137

sp|P03929|ATP8_BOVIN
ATP synthase protein 8
Search

ATP8

0.49	ATP synthase protein 8

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.34	GO:0016887	ATPase activity

0.78	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
0.30	GO:0016021	integral component of membrane

0.34

GO:0016887

sp|P03968|FGF1_BOVIN
Fibroblast growth factor 1
Search

FGF1

0.54	Fibroblast growth factor 1

0.84	GO:0008543	fibroblast growth factor receptor signaling pathway
0.76	GO:0010469	regulation of receptor activity
0.66	GO:0051781	positive regulation of cell division
0.65	GO:0001525	angiogenesis
0.64	GO:0060681	branch elongation involved in ureteric bud branching
0.63	GO:0045542	positive regulation of cholesterol biosynthetic process
0.62	GO:0045766	positive regulation of angiogenesis
0.60	GO:1901509	regulation of endothelial tube morphogenesis
0.60	GO:0010595	positive regulation of endothelial cell migration
0.60	GO:1903670	regulation of sprouting angiogenesis

0.84	GO:0005104	fibroblast growth factor receptor binding
0.78	GO:0008083	growth factor activity
0.66	GO:0008201	heparin binding
0.60	GO:0044548	S100 protein binding
0.59	GO:0005178	integrin binding
0.44	GO:0030544	Hsp70 protein binding
0.41	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.40	GO:0016303	1-phosphatidylinositol-3-kinase activity
0.40	GO:0090722	receptor-receptor interaction
0.39	GO:0042056	chemoattractant activity

0.66	GO:0005576	extracellular region
0.58	GO:0005938	cell cortex
0.54	GO:0005829	cytosol
0.51	GO:0005634	nucleus
0.39	GO:0070013	intracellular organelle lumen
0.37	GO:0043232	intracellular non-membrane-bounded organelle
0.37	GO:0044446	intracellular organelle part

0.41	EC:2.7.1.153	GO:0046934
0.41	KEGG:R04545	GO:0046934

sp|P03969|FGF2_BOVIN
Fibroblast growth factor 2
Search

FGF2

0.61	Fibroblast growth factor

0.84	GO:0008543	fibroblast growth factor receptor signaling pathway
0.76	GO:0010469	regulation of receptor activity
0.64	GO:0001525	angiogenesis
0.61	GO:0051781	positive regulation of cell division
0.58	GO:0045766	positive regulation of angiogenesis
0.57	GO:0030154	cell differentiation
0.57	GO:0001759	organ induction
0.57	GO:0010595	positive regulation of endothelial cell migration
0.55	GO:0042127	regulation of cell proliferation
0.55	GO:0035295	tube development

0.85	GO:0005104	fibroblast growth factor receptor binding
0.78	GO:0008083	growth factor activity
0.61	GO:0008201	heparin binding
0.50	GO:0044548	S100 protein binding
0.49	GO:0005178	integrin binding
0.39	GO:0090722	receptor-receptor interaction
0.38	GO:0042056	chemoattractant activity
0.38	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.37	GO:0005125	cytokine activity
0.37	GO:0030544	Hsp70 protein binding

0.66	GO:0005576	extracellular region
0.54	GO:0005938	cell cortex
0.50	GO:0005829	cytosol
0.48	GO:0005634	nucleus
0.36	GO:0070013	intracellular organelle lumen
0.34	GO:0043232	intracellular non-membrane-bounded organelle
0.34	GO:0044446	intracellular organelle part

0.36	EC:2.7.1.153	GO:0046934
0.36	KEGG:R04545	GO:0046934

sp|P03972|MIS_BOVIN
Muellerian-inhibiting factor
Search

AMH

0.86	Anti-Mullerian hormone

0.82	GO:0008406	gonad development
0.76	GO:0010469	regulation of receptor activity
0.73	GO:0001880	Mullerian duct regression
0.56	GO:0010628	positive regulation of gene expression
0.45	GO:0001655	urogenital system development
0.43	GO:2000355	negative regulation of ovarian follicle development
0.43	GO:0048162	multi-layer follicle stage
0.41	GO:0022602	ovulation cycle process
0.41	GO:0046545	development of primary female sexual characteristics
0.41	GO:0051092	positive regulation of NF-kappaB transcription factor activity

0.78	GO:0008083	growth factor activity
0.41	GO:0005160	transforming growth factor beta receptor binding
0.40	GO:0005179	hormone activity

0.65	GO:0005576	extracellular region
0.37	GO:0060473	cortical granule
0.35	GO:0005783	endoplasmic reticulum

sp|P04038|COX6C_BOVIN
Cytochrome c oxidase subunit 6C
Search

COX6C

0.95	Cytochrome c oxidase polypeptide VIc

0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0022900	electron transport chain
0.34	GO:0006119	oxidative phosphorylation
0.34	GO:0009060	aerobic respiration

0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016675	oxidoreductase activity, acting on a heme group of donors
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity

0.50	GO:0031966	mitochondrial membrane
0.50	GO:0019866	organelle inner membrane
0.39	GO:0045277	respiratory chain complex IV
0.36	GO:0098798	mitochondrial protein complex
0.30	GO:0016021	integral component of membrane

0.65

GO:0016675

sp|P04116|MYPR_BOVIN
Myelin proteolipid protein
Search

PLP1

0.93	Myelin proteolipid protein B

0.62	GO:0022010	central nervous system myelination
0.62	GO:0014002	astrocyte development
0.61	GO:0042759	long-chain fatty acid biosynthetic process
0.58	GO:0048469	cell maturation
0.57	GO:0006954	inflammatory response
0.56	GO:0061564	axon development
0.53	GO:0010628	positive regulation of gene expression
0.41	GO:0007229	integrin-mediated signaling pathway
0.39	GO:0021762	substantia nigra development
0.35	GO:0007268	chemical synaptic transmission

0.43	GO:0019911	structural constituent of myelin sheath
0.38	GO:0042802	identical protein binding

0.60	GO:0043209	myelin sheath
0.45	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P04258|CO3A1_BOVIN
Collagen alpha-1(III) chain
Search

COL3A1

0.88	Collagen type III alpha 1 chain

0.63	GO:0030199	collagen fibril organization
0.61	GO:0043588	skin development
0.61	GO:0071230	cellular response to amino acid stimulus
0.60	GO:0060414	aorta smooth muscle tissue morphogenesis
0.60	GO:2001223	negative regulation of neuron migration
0.58	GO:0060322	head development
0.58	GO:0035025	positive regulation of Rho protein signal transduction
0.57	GO:0018149	peptide cross-linking
0.57	GO:0071560	cellular response to transforming growth factor beta stimulus
0.55	GO:0042060	wound healing

0.79	GO:0005201	extracellular matrix structural constituent
0.66	GO:0048407	platelet-derived growth factor binding
0.62	GO:0002020	protease binding
0.57	GO:0005178	integrin binding
0.56	GO:0046332	SMAD binding
0.45	GO:0042802	identical protein binding
0.36	GO:0046872	metal ion binding

0.73	GO:0005581	collagen trimer
0.65	GO:0098643	banded collagen fibril
0.56	GO:0005615	extracellular space
0.37	GO:0030141	secretory granule
0.37	GO:0005783	endoplasmic reticulum
0.36	GO:0005794	Golgi apparatus
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|P04260|K2C4_BOVIN
Keratin, type II cytoskeletal 59 kDa, component IV (Fragment)
Search

0.87	Keratin, type II cytoskeletal 6A

0.46	GO:0002244	hematopoietic progenitor cell differentiation
0.42	GO:0031424	keratinization
0.38	GO:0012501	programmed cell death
0.38	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.38	GO:0051803	negative regulation of cytolysis in other organism involved in symbiotic interaction
0.38	GO:0001898	regulation of cytolysis by symbiont of host cells
0.38	GO:0007010	cytoskeleton organization
0.38	GO:0045103	intermediate filament-based process
0.38	GO:0002009	morphogenesis of an epithelium
0.38	GO:0050830	defense response to Gram-positive bacterium

0.62	GO:0005198	structural molecule activity
0.49	GO:0097110	scaffold protein binding

0.82	GO:0045095	keratin filament
0.40	GO:0070062	extracellular exosome
0.40	GO:0005739	mitochondrion
0.38	GO:0005886	plasma membrane
0.37	GO:0005829	cytosol
0.34	GO:0005634	nucleus
0.33	GO:0036338	viral membrane

sp|P04261|K2C3_BOVIN
Keratin, type II cytoskeletal 60 kDa, component III (Fragment)
Search

0.92	Keratin, type II cytoskeletal 60 kDa, component III (Fragment)

0.41	GO:0030154	cell differentiation
0.41	GO:0048513	animal organ development
0.39	GO:0002376	immune system process
0.39	GO:0060429	epithelium development
0.38	GO:0008544	epidermis development
0.37	GO:0045109	intermediate filament organization
0.36	GO:0050830	defense response to Gram-positive bacterium
0.36	GO:0031581	hemidesmosome assembly
0.36	GO:0050680	negative regulation of epithelial cell proliferation
0.36	GO:0043901	negative regulation of multi-organism process

0.61	GO:0005198	structural molecule activity
0.57	GO:0097110	scaffold protein binding
0.33	GO:0030414	peptidase inhibitor activity

0.80	GO:0045095	keratin filament
0.44	GO:0005739	mitochondrion
0.42	GO:0005886	plasma membrane
0.38	GO:0070062	extracellular exosome
0.34	GO:0005829	cytosol
0.34	GO:0005634	nucleus
0.34	GO:0036338	viral membrane
0.33	GO:0005578	proteinaceous extracellular matrix
0.33	GO:0042579	microbody
0.30	GO:0031224	intrinsic component of membrane

sp|P04262|K2CB_BOVIN
Keratin, type II cytoskeletal 68 kDa, component IB (Fragment)
Search

0.91	Keratin, type II cytoskeletal 68 kDa, component IB (Fragment)

0.53	GO:0045104	intermediate filament cytoskeleton organization
0.48	GO:0048733	sebaceous gland development
0.47	GO:0008544	epidermis development
0.45	GO:0043473	pigmentation
0.43	GO:0030154	cell differentiation
0.41	GO:0060429	epithelium development
0.41	GO:0030097	hemopoiesis
0.38	GO:0032980	keratinocyte activation
0.38	GO:0051546	keratinocyte migration
0.37	GO:0043616	keratinocyte proliferation

0.62	GO:0005198	structural molecule activity
0.37	GO:0005515	protein binding
0.34	GO:0044877	macromolecular complex binding

0.82	GO:0045095	keratin filament
0.38	GO:0070062	extracellular exosome
0.37	GO:0001533	cornified envelope
0.36	GO:0009986	cell surface
0.35	GO:0005829	cytosol
0.34	GO:0043231	intracellular membrane-bounded organelle

sp|P04263|K2CA_BOVIN
Keratin, type II cytoskeletal 68 kDa, component IA (Fragment)
Search

0.83	Keratin, type II cytoskeletal 6A

0.51	GO:0043588	skin development
0.48	GO:0008544	epidermis development
0.45	GO:0043473	pigmentation
0.45	GO:0045104	intermediate filament cytoskeleton organization
0.44	GO:0048732	gland development
0.43	GO:0018149	peptide cross-linking
0.42	GO:0030855	epithelial cell differentiation
0.42	GO:0033561	regulation of water loss via skin
0.41	GO:0050728	negative regulation of inflammatory response
0.41	GO:0006959	humoral immune response

0.62	GO:0005198	structural molecule activity
0.37	GO:0030246	carbohydrate binding
0.37	GO:0005515	protein binding
0.33	GO:0004872	receptor activity

0.82	GO:0045095	keratin filament
0.44	GO:0001533	cornified envelope
0.39	GO:0070062	extracellular exosome
0.37	GO:0005829	cytosol
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0009986	cell surface
0.35	GO:0072562	blood microparticle
0.35	GO:0005634	nucleus
0.34	GO:0031012	extracellular matrix

sp|P04272|ANXA2_BOVIN
Annexin A2
Search

ANXA2

0.60

Annexin

0.72	GO:0043086	negative regulation of catalytic activity
0.60	GO:0052362	catabolism by host of symbiont protein
0.59	GO:0044147	negative regulation of development of symbiont involved in interaction with host
0.59	GO:1905597	positive regulation of low-density lipoprotein particle receptor binding
0.59	GO:1905599	positive regulation of low-density lipoprotein receptor activity
0.59	GO:1905581	positive regulation of low-density lipoprotein particle clearance
0.59	GO:1905602	positive regulation of receptor-mediated endocytosis involved in cholesterol transport
0.59	GO:0032804	negative regulation of low-density lipoprotein particle receptor catabolic process
0.58	GO:0036035	osteoclast development
0.58	GO:0052405	negative regulation by host of symbiont molecular function

0.85	GO:0004859	phospholipase inhibitor activity
0.81	GO:0005544	calcium-dependent phospholipid binding
0.71	GO:0008092	cytoskeletal protein binding
0.69	GO:0005509	calcium ion binding
0.57	GO:0098641	cadherin binding involved in cell-cell adhesion
0.56	GO:0044548	S100 protein binding
0.55	GO:0048306	calcium-dependent protein binding
0.55	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.54	GO:0002020	protease binding
0.50	GO:0042802	identical protein binding

0.59	GO:1990667	PCSK9-AnxA2 complex
0.54	GO:0005913	cell-cell adherens junction
0.54	GO:0035749	myelin sheath adaxonal region
0.54	GO:0031902	late endosome membrane
0.54	GO:0030496	midbody
0.53	GO:0005811	lipid droplet
0.53	GO:0070062	extracellular exosome
0.53	GO:0005765	lysosomal membrane
0.53	GO:0043220	Schmidt-Lanterman incisure
0.53	GO:0098857	membrane microdomain

sp|P04394|NDUV2_BOVIN
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial
Search

NDUFV2

0.87	NADH:ubiquinone oxidoreductase core subunit V2

0.76	GO:0048738	cardiac muscle tissue development
0.70	GO:0006120	mitochondrial electron transport, NADH to ubiquinone
0.68	GO:0007399	nervous system development

0.70	GO:0051537	2 iron, 2 sulfur cluster binding
0.65	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.54	GO:0046872	metal ion binding

0.76	GO:0005747	mitochondrial respiratory chain complex I
0.59	GO:0045272	plasma membrane respiratory chain complex I
0.57	GO:0043209	myelin sheath

0.65

GO:0008137

sp|P04409|KPCA_BOVIN
Protein kinase C alpha type
Search

PRKCA

0.76	Protein kinase C alpha type

0.64	GO:0035408	histone H3-T6 phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.59	GO:0045766	positive regulation of angiogenesis
0.59	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway
0.59	GO:0034351	negative regulation of glial cell apoptotic process
0.58	GO:0090330	regulation of platelet aggregation
0.57	GO:0002159	desmosome assembly
0.56	GO:0001938	positive regulation of endothelial cell proliferation
0.56	GO:0010595	positive regulation of endothelial cell migration
0.55	GO:0043535	regulation of blood vessel endothelial cell migration

0.82	GO:0004697	protein kinase C activity
0.64	GO:0035403	histone kinase activity (H3-T6 specific)
0.62	GO:0008270	zinc ion binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.52	GO:0019899	enzyme binding
0.46	GO:0050681	androgen receptor binding
0.45	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity

0.51	GO:0005829	cytosol
0.49	GO:0005886	plasma membrane
0.48	GO:0005783	endoplasmic reticulum
0.41	GO:0005654	nucleoplasm
0.39	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0070062	extracellular exosome
0.38	GO:0001750	photoreceptor outer segment
0.36	GO:0043025	neuronal cell body
0.36	GO:0030425	dendrite
0.36	GO:0045177	apical part of cell

0.82

EC:2.7.11.13

GO:0004697

sp|P04421|LYSC_BOVIN
Lysozyme C
Search

LYZ

0.51	Lysozyme C, non-stomach isozyme

0.78	GO:0042742	defense response to bacterium
0.77	GO:0019835	cytolysis
0.46	GO:0007586	digestion
0.45	GO:0031640	killing of cells of other organism
0.45	GO:0016998	cell wall macromolecule catabolic process
0.34	GO:0043312	neutrophil degranulation
0.34	GO:0001895	retina homeostasis
0.34	GO:0019730	antimicrobial humoral response
0.34	GO:0006954	inflammatory response
0.32	GO:0044267	cellular protein metabolic process

0.78	GO:0003796	lysozyme activity
0.43	GO:0042802	identical protein binding

0.49	GO:0005576	extracellular region
0.35	GO:1904724	tertiary granule lumen
0.35	GO:0035580	specific granule lumen
0.35	GO:0035578	azurophil granule lumen

0.78

EC:3.2.1.17

GO:0003796

sp|P04467|CALB1_BOVIN
Calbindin
Search

CALB1

0.96	Cerebellar calbindin

0.74	GO:0055074	calcium ion homeostasis
0.61	GO:0072027	connecting tubule development
0.60	GO:0072221	metanephric distal convoluted tubule development
0.60	GO:0035502	metanephric part of ureteric bud development
0.60	GO:0072205	metanephric collecting duct development
0.59	GO:0007614	short-term memory
0.58	GO:1900271	regulation of long-term synaptic potentiation
0.58	GO:0007616	long-term memory
0.58	GO:0010842	retina layer formation
0.55	GO:0007626	locomotory behavior

0.70	GO:0005509	calcium ion binding
0.46	GO:0008270	zinc ion binding
0.43	GO:0005499	vitamin D binding
0.33	GO:0005515	protein binding

0.55	GO:0043005	neuron projection
0.55	GO:0043025	neuronal cell body
0.54	GO:0045202	synapse
0.53	GO:0120038	plasma membrane bounded cell projection part
0.52	GO:0005829	cytosol
0.47	GO:0005634	nucleus
0.43	GO:0005921	gap junction
0.36	GO:0070062	extracellular exosome
0.34	GO:0098590	plasma membrane region
0.34	GO:0012506	vesicle membrane

sp|P04557|SFP3_BOVIN
Seminal plasma protein A3
Search

0.89	Binder of sperm protein homolog 1

0.84	GO:0048240	sperm capacitation
0.59	GO:1902492	positive regulation of sperm capacitation
0.55	GO:0033700	phospholipid efflux
0.52	GO:0007338	single fertilization
0.47	GO:0030574	collagen catabolic process
0.45	GO:0050900	leukocyte migration
0.45	GO:0001503	ossification
0.39	GO:0006508	proteolysis

0.63	GO:0008201	heparin binding
0.41	GO:0004222	metalloendopeptidase activity
0.40	GO:0008270	zinc ion binding
0.38	GO:0005509	calcium ion binding
0.37	GO:0003677	DNA binding

0.67	GO:0044421	extracellular region part
0.58	GO:0009986	cell surface
0.30	GO:0031224	intrinsic component of membrane

0.41

GO:0004222

sp|P04651|LSHB_BOVIN
Lutropin subunit beta
Search

LHB

0.92	LOW QUALITY PROTEIN: lutropin subunit beta

0.76	GO:0010469	regulation of receptor activity
0.58	GO:0030728	ovulation
0.52	GO:0007267	cell-cell signaling
0.52	GO:0009755	hormone-mediated signaling pathway
0.49	GO:0007186	G-protein coupled receptor signaling pathway
0.42	GO:0030823	regulation of cGMP metabolic process
0.40	GO:0010817	regulation of hormone levels
0.38	GO:0015850	organic hydroxy compound transport
0.38	GO:0008584	male gonad development
0.38	GO:0006869	lipid transport

0.79

GO:0005179

hormone activity

0.66	GO:0005576	extracellular region
0.39	GO:0005737	cytoplasm
0.39	GO:0031982	vesicle
0.36	GO:0012505	endomembrane system
0.36	GO:0031974	membrane-enclosed lumen
0.34	GO:0044446	intracellular organelle part
0.34	GO:0043231	intracellular membrane-bounded organelle

sp|P04695|GNAT1_BOVIN
Guanine nucleotide-binding protein G(t) subunit alpha-1
Search

GNAT1

0.79	Short photoreceptor transducin-alpha subunit

0.82	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.62	GO:0050917	sensory perception of umami taste
0.59	GO:0050908	detection of light stimulus involved in visual perception
0.57	GO:0042462	eye photoreceptor cell development
0.56	GO:0060041	retina development in camera-type eye
0.55	GO:0071257	cellular response to electrical stimulus
0.55	GO:0007603	phototransduction, visible light
0.51	GO:0008283	cell proliferation
0.50	GO:0050913	sensory perception of bitter taste
0.47	GO:0050916	sensory perception of sweet taste

0.81	GO:0031683	G-protein beta/gamma-subunit complex binding
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.64	GO:0004871	signal transducer activity
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0001664	G-protein coupled receptor binding
0.37	GO:0000035	acyl binding
0.36	GO:0019901	protein kinase binding

0.60	GO:0001917	photoreceptor inner segment
0.59	GO:0001750	photoreceptor outer segment
0.53	GO:0032391	photoreceptor connecting cilium
0.49	GO:1905360	GTPase complex
0.49	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.44	GO:0098797	plasma membrane protein complex
0.41	GO:0098590	plasma membrane region
0.41	GO:0045177	apical part of cell
0.38	GO:0030141	secretory granule
0.38	GO:0043025	neuronal cell body

sp|P04696|GNAT2_BOVIN
Guanine nucleotide-binding protein G(t) subunit alpha-2
Search

GNAT2

0.94	Guanine nucleotide-binding protein Gt subunit alpha-X

0.82	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.64	GO:0050908	detection of light stimulus involved in visual perception
0.60	GO:0042462	eye photoreceptor cell development
0.59	GO:0050909	sensory perception of taste
0.58	GO:0060041	retina development in camera-type eye
0.56	GO:0007602	phototransduction
0.55	GO:0048593	camera-type eye morphogenesis
0.49	GO:0050907	detection of chemical stimulus involved in sensory perception
0.47	GO:0071257	cellular response to electrical stimulus
0.44	GO:0008283	cell proliferation

0.81	GO:0031683	G-protein beta/gamma-subunit complex binding
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.64	GO:0004871	signal transducer activity
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0001664	G-protein coupled receptor binding
0.37	GO:0000035	acyl binding
0.36	GO:0046872	metal ion binding

0.64	GO:0001917	photoreceptor inner segment
0.63	GO:0001750	photoreceptor outer segment
0.52	GO:1905360	GTPase complex
0.52	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.46	GO:0043234	protein complex
0.46	GO:0032391	photoreceptor connecting cilium
0.41	GO:0098590	plasma membrane region
0.40	GO:0045177	apical part of cell
0.38	GO:0030141	secretory granule
0.38	GO:0097223	sperm part

sp|P04758|ACHB_BOVIN
Acetylcholine receptor subunit beta
Search

CHRNB1

0.97	Acetylcholine receptor subunit beta

0.79	GO:0060079	excitatory postsynaptic potential
0.62	GO:0007271	synaptic transmission, cholinergic
0.60	GO:0034220	ion transmembrane transport
0.60	GO:0035095	behavioral response to nicotine
0.59	GO:0007274	neuromuscular synaptic transmission
0.58	GO:0001941	postsynaptic membrane organization
0.56	GO:0048747	muscle fiber development
0.56	GO:0006936	muscle contraction
0.51	GO:0050877	nervous system process
0.46	GO:0006812	cation transport

0.82	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0004888	transmembrane signaling receptor activity
0.60	GO:0042166	acetylcholine binding
0.33	GO:0005515	protein binding

0.78	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.64	GO:0005892	acetylcholine-gated channel complex
0.35	GO:0009897	external side of plasma membrane
0.35	GO:0043204	perikaryon
0.34	GO:0030425	dendrite
0.34	GO:0030424	axon
0.32	GO:0005737	cytoplasm

sp|P04759|ACHD_BOVIN
Acetylcholine receptor subunit delta
Search

CHRND

0.89	Acetylcholine receptor subunit delta

0.77	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.51	GO:0035094	response to nicotine
0.51	GO:0007271	synaptic transmission, cholinergic
0.51	GO:0007274	neuromuscular synaptic transmission
0.49	GO:0048630	skeletal muscle tissue growth
0.49	GO:0050881	musculoskeletal movement
0.43	GO:0006936	muscle contraction
0.40	GO:0006812	cation transport
0.37	GO:0050905	neuromuscular process

0.80	GO:0022848	acetylcholine-gated cation-selective channel activity
0.69	GO:0099600	transmembrane receptor activity
0.54	GO:0042166	acetylcholine binding
0.37	GO:0004252	serine-type endopeptidase activity
0.35	GO:0005515	protein binding

0.77	GO:0045211	postsynaptic membrane
0.72	GO:0030054	cell junction
0.53	GO:0005892	acetylcholine-gated channel complex
0.42	GO:0005654	nucleoplasm
0.42	GO:0005829	cytosol

0.37

GO:0004252

sp|P04815|BPT2_BOVIN
Spleen trypsin inhibitor I
Search

0.58	Pancreatic trypsin inhibitor

0.76	GO:0010951	negative regulation of endopeptidase activity
0.41	GO:0006508	proteolysis
0.40	GO:0050878	regulation of body fluid levels
0.39	GO:0070495	negative regulation of thrombin-activated receptor signaling pathway
0.39	GO:1902572	negative regulation of serine-type peptidase activity
0.39	GO:1900003	regulation of serine-type endopeptidase activity
0.39	GO:0034111	negative regulation of homotypic cell-cell adhesion
0.38	GO:0006030	chitin metabolic process
0.38	GO:0050819	negative regulation of coagulation
0.38	GO:0061045	negative regulation of wound healing

0.79	GO:0004867	serine-type endopeptidase inhibitor activity
0.40	GO:0008233	peptidase activity
0.39	GO:0035375	zymogen binding
0.39	GO:0043199	sulfate binding
0.39	GO:0019870	potassium channel inhibitor activity
0.38	GO:0008061	chitin binding
0.38	GO:0002020	protease binding
0.37	GO:0005509	calcium ion binding
0.36	GO:0046982	protein heterodimerization activity
0.35	GO:0097108	hedgehog family protein binding

0.47	GO:0005576	extracellular region
0.39	GO:0097180	serine protease inhibitor complex
0.34	GO:0005581	collagen trimer
0.30	GO:0016020	membrane

0.40

GO:0008233

sp|P04836|CBPE_BOVIN
Carboxypeptidase E
Search

CPE

0.96	Carboxypeptidase E

0.62	GO:0030070	insulin processing
0.59	GO:0003214	cardiac left ventricle morphogenesis
0.53	GO:0016055	Wnt signaling pathway
0.51	GO:0072657	protein localization to membrane
0.36	GO:2000173	negative regulation of branching morphogenesis of a nerve
0.36	GO:0034230	enkephalin processing
0.35	GO:0007218	neuropeptide signaling pathway
0.35	GO:0043171	peptide catabolic process
0.33	GO:0036211	protein modification process
0.33	GO:0044267	cellular protein metabolic process

0.75	GO:0004181	metallocarboxypeptidase activity
0.61	GO:0008270	zinc ion binding
0.58	GO:0042043	neurexin family protein binding
0.54	GO:0050839	cell adhesion molecule binding
0.45	GO:0004185	serine-type carboxypeptidase activity
0.35	GO:0050897	cobalt ion binding
0.34	GO:0019904	protein domain specific binding

0.52	GO:0005615	extracellular space
0.51	GO:0005794	Golgi apparatus
0.47	GO:0043025	neuronal cell body
0.47	GO:0030141	secretory granule
0.46	GO:0097060	synaptic membrane
0.41	GO:0030658	transport vesicle membrane
0.37	GO:1903561	extracellular vesicle
0.35	GO:0030425	dendrite
0.35	GO:0045121	membrane raft
0.33	GO:0005634	nucleus

0.75

GO:0004181

sp|P04837|FSHB_BOVIN
Follitropin subunit beta
Search

FSHB

0.95	Follicle stimulating hormone beta subunit

0.76	GO:0010469	regulation of receptor activity
0.58	GO:0042699	follicle-stimulating hormone signaling pathway
0.58	GO:0060011	Sertoli cell proliferation
0.57	GO:0007179	transforming growth factor beta receptor signaling pathway
0.57	GO:0045780	positive regulation of bone resorption
0.55	GO:0045670	regulation of osteoclast differentiation
0.49	GO:0010628	positive regulation of gene expression
0.45	GO:0007267	cell-cell signaling
0.45	GO:0009755	hormone-mediated signaling pathway
0.38	GO:0009914	hormone transport

0.79

GO:0005179

hormone activity

0.66	GO:0005576	extracellular region
0.40	GO:0005737	cytoplasm
0.35	GO:0031982	vesicle
0.33	GO:0043234	protein complex
0.30	GO:0016020	membrane

sp|P04896|GNAS2_BOVIN
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
Search

GNAS

0.80	Guanine nucleotide-binding protein alpha-stimulating activity polypeptide 1

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.54	GO:0043950	positive regulation of cAMP-mediated signaling
0.53	GO:0030819	positive regulation of cAMP biosynthetic process
0.53	GO:0019933	cAMP-mediated signaling
0.50	GO:0060789	hair follicle placode formation
0.49	GO:2000828	regulation of parathyroid hormone secretion
0.48	GO:0043547	positive regulation of GTPase activity
0.48	GO:0040032	post-embryonic body morphogenesis
0.48	GO:0070527	platelet aggregation
0.47	GO:0045672	positive regulation of osteoclast differentiation

0.81	GO:0031683	G-protein beta/gamma-subunit complex binding
0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.64	GO:0004871	signal transducer activity
0.51	GO:0031852	mu-type opioid receptor binding
0.51	GO:0051430	corticotropin-releasing hormone receptor 1 binding
0.50	GO:0031698	beta-2 adrenergic receptor binding
0.50	GO:0031748	D1 dopamine receptor binding
0.49	GO:0035255	ionotropic glutamate receptor binding
0.49	GO:0005159	insulin-like growth factor receptor binding

0.48	GO:1905360	GTPase complex
0.48	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.45	GO:0032588	trans-Golgi network membrane
0.45	GO:0030425	dendrite
0.43	GO:0098797	plasma membrane protein complex
0.42	GO:0070062	extracellular exosome
0.42	GO:0005829	cytosol
0.42	GO:0048471	perinuclear region of cytoplasm
0.41	GO:0016324	apical plasma membrane
0.39	GO:0042383	sarcolemma

0.44

GO:0047391

sp|P04972|CNRG_BOVIN
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma
Search

PDE6G

0.96	Retinal rod rhodopsin-sensitive cgmp 3'5'-cyclic phosphodiesterase subunit gamma

0.77	GO:0007601	visual perception
0.52	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway
0.52	GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway
0.50	GO:0000187	activation of MAPK activity
0.38	GO:0050896	response to stimulus
0.36	GO:0022400	regulation of rhodopsin mediated signaling pathway
0.36	GO:0043086	negative regulation of catalytic activity
0.35	GO:0198738	cell-cell signaling by wnt

0.85	GO:0030553	cGMP binding
0.78	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.39	GO:0030507	spectrin binding
0.36	GO:0004857	enzyme inhibitor activity
0.34	GO:0008270	zinc ion binding

0.38	GO:0097381	photoreceptor disc membrane
0.36	GO:0042622	photoreceptor outer segment membrane

0.78

GO:0004114

sp|P04973|CLCA_BOVIN
Clathrin light chain A
Search

CLTA

0.68	Clathrin light chain A

0.69	GO:0006886	intracellular protein transport
0.69	GO:0016192	vesicle-mediated transport
0.53	GO:0048268	clathrin coat assembly
0.45	GO:0098657	import into cell
0.37	GO:0051301	cell division
0.37	GO:0007049	cell cycle
0.37	GO:0032802	low-density lipoprotein particle receptor catabolic process
0.36	GO:0034383	low-density lipoprotein particle clearance
0.36	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.35	GO:0007018	microtubule-based movement

0.62	GO:0005198	structural molecule activity
0.59	GO:0032050	clathrin heavy chain binding
0.39	GO:0042277	peptide binding
0.38	GO:0032403	protein complex binding
0.38	GO:0051020	GTPase binding

0.83	GO:0030130	clathrin coat of trans-Golgi network vesicle
0.82	GO:0030132	clathrin coat of coated pit
0.54	GO:0071439	clathrin complex
0.40	GO:0030672	synaptic vesicle membrane
0.40	GO:0099631	postsynaptic endocytic zone cytoplasmic component
0.39	GO:0005819	spindle
0.38	GO:0045334	clathrin-coated endocytic vesicle
0.37	GO:0036020	endolysosome membrane
0.36	GO:0005802	trans-Golgi network
0.36	GO:0030666	endocytic vesicle membrane

sp|P04975|CLCB_BOVIN
Clathrin light chain B
Search

CLTB

0.67	Clathrin light chain B

0.69	GO:0006886	intracellular protein transport
0.69	GO:0016192	vesicle-mediated transport
0.45	GO:0098657	import into cell
0.43	GO:0048268	clathrin coat assembly
0.35	GO:0036465	synaptic vesicle recycling
0.35	GO:0097480	establishment of synaptic vesicle localization
0.35	GO:0061024	membrane organization
0.35	GO:0099643	signal release from synapse
0.35	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.35	GO:0016050	vesicle organization

0.62	GO:0005198	structural molecule activity
0.55	GO:0032050	clathrin heavy chain binding
0.39	GO:0042277	peptide binding
0.35	GO:0005326	neurotransmitter transporter activity
0.34	GO:0000287	magnesium ion binding
0.34	GO:0032403	protein complex binding
0.34	GO:0051020	GTPase binding

0.83	GO:0030130	clathrin coat of trans-Golgi network vesicle
0.82	GO:0030132	clathrin coat of coated pit
0.56	GO:0060170	ciliary membrane
0.53	GO:0005802	trans-Golgi network
0.48	GO:0005829	cytosol
0.43	GO:0071439	clathrin complex
0.36	GO:0098793	presynapse
0.35	GO:0045334	clathrin-coated endocytic vesicle
0.34	GO:0099501	exocytic vesicle membrane
0.34	GO:0005819	spindle

sp|P04985|ELN_BOVIN
Elastin
Search

ELN

0.97

Elastin

0.53	GO:0043149	stress fiber assembly
0.51	GO:0007519	skeletal muscle tissue development
0.50	GO:0030198	extracellular matrix organization
0.49	GO:0030833	regulation of actin filament polymerization
0.38	GO:0071298	cellular response to L-ascorbic acid
0.37	GO:0071280	cellular response to copper ion
0.37	GO:0071549	cellular response to dexamethasone stimulus
0.37	GO:0055093	response to hyperoxia
0.37	GO:0007585	respiratory gaseous exchange
0.37	GO:0001974	blood vessel remodeling

0.79	GO:0005201	extracellular matrix structural constituent
0.51	GO:0050840	extracellular matrix binding
0.38	GO:0005515	protein binding
0.37	GO:0097493	structural molecule activity conferring elasticity
0.35	GO:0016740	transferase activity
0.35	GO:0008234	cysteine-type peptidase activity
0.33	GO:0046872	metal ion binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.73	GO:0005578	proteinaceous extracellular matrix
0.58	GO:0071953	elastic fiber
0.42	GO:0005739	mitochondrion
0.38	GO:0005581	collagen trimer
0.35	GO:0005615	extracellular space
0.32	GO:0019867	outer membrane
0.30	GO:0016021	integral component of membrane

0.35

GO:0016740

sp|P05007|IFNAA_BOVIN
Interferon alpha-A
Search

0.88	Interferon alpha-A

0.78	GO:0051607	defense response to virus
0.76	GO:0010469	regulation of receptor activity
0.58	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein
0.58	GO:0002323	natural killer cell activation involved in immune response
0.57	GO:0042100	B cell proliferation
0.57	GO:0002286	T cell activation involved in immune response
0.56	GO:0043330	response to exogenous dsRNA
0.56	GO:0030183	B cell differentiation
0.55	GO:0002250	adaptive immune response
0.54	GO:0006959	humoral immune response

0.81	GO:0005125	cytokine activity
0.79	GO:0005126	cytokine receptor binding
0.51	GO:0032403	protein complex binding

0.73	GO:0005615	extracellular space
0.31	GO:0005622	intracellular

sp|P05008|IFNAB_BOVIN
Interferon alpha-B
Search

0.88	Interferon alpha-B

0.78	GO:0051607	defense response to virus
0.76	GO:0010469	regulation of receptor activity
0.59	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein
0.59	GO:0002323	natural killer cell activation involved in immune response
0.58	GO:0042100	B cell proliferation
0.57	GO:0002286	T cell activation involved in immune response
0.57	GO:0043330	response to exogenous dsRNA
0.57	GO:0030183	B cell differentiation
0.55	GO:0002250	adaptive immune response
0.55	GO:0006959	humoral immune response

0.81	GO:0005125	cytokine activity
0.79	GO:0005126	cytokine receptor binding
0.52	GO:0032403	protein complex binding

0.73	GO:0005615	extracellular space
0.31	GO:0005622	intracellular

sp|P05009|IFNAC_BOVIN
Interferon alpha-C
Search

0.88	Interferon alpha-C

0.78	GO:0051607	defense response to virus
0.76	GO:0010469	regulation of receptor activity
0.60	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein
0.60	GO:0002323	natural killer cell activation involved in immune response
0.59	GO:0042100	B cell proliferation
0.58	GO:0002286	T cell activation involved in immune response
0.58	GO:0043330	response to exogenous dsRNA
0.58	GO:0030183	B cell differentiation
0.56	GO:0002250	adaptive immune response
0.56	GO:0006959	humoral immune response

0.81	GO:0005125	cytokine activity
0.79	GO:0005126	cytokine receptor binding
0.52	GO:0032403	protein complex binding

0.73	GO:0005615	extracellular space
0.31	GO:0005622	intracellular

sp|P05010|IFNAD_BOVIN
Interferon alpha-D
Search

0.88	Interferon alpha-D

0.78	GO:0051607	defense response to virus
0.76	GO:0010469	regulation of receptor activity
0.59	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein
0.59	GO:0002323	natural killer cell activation involved in immune response
0.58	GO:0042100	B cell proliferation
0.57	GO:0002286	T cell activation involved in immune response
0.57	GO:0043330	response to exogenous dsRNA
0.56	GO:0030183	B cell differentiation
0.55	GO:0002250	adaptive immune response
0.55	GO:0006959	humoral immune response

0.81	GO:0005125	cytokine activity
0.79	GO:0005126	cytokine receptor binding
0.51	GO:0032403	protein complex binding

0.73	GO:0005615	extracellular space
0.31	GO:0005622	intracellular

sp|P05016|IL2_BOVIN
Interleukin-2
Search

IL2

0.96	Interleukin-2

0.83	GO:0002250	adaptive immune response
0.76	GO:0010469	regulation of receptor activity
0.58	GO:0002903	negative regulation of B cell apoptotic process
0.58	GO:0042104	positive regulation of activated T cell proliferation
0.58	GO:0032740	positive regulation of interleukin-17 production
0.58	GO:0046013	regulation of T cell homeostatic proliferation
0.57	GO:2000320	negative regulation of T-helper 17 cell differentiation
0.57	GO:0051024	positive regulation of immunoglobulin secretion
0.57	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein
0.57	GO:0030890	positive regulation of B cell proliferation

0.87	GO:0005134	interleukin-2 receptor binding
0.80	GO:0005125	cytokine activity
0.78	GO:0008083	growth factor activity
0.39	GO:0031851	kappa-type opioid receptor binding
0.38	GO:0043208	glycosphingolipid binding
0.36	GO:0019209	kinase activator activity
0.35	GO:0030246	carbohydrate binding
0.34	GO:0005088	Ras guanyl-nucleotide exchange factor activity

0.73	GO:0005615	extracellular space
0.32	GO:0005622	intracellular

sp|P05059|CMGA_BOVIN
Chromogranin-A
Search

CHGA

0.97	Chromogranin-A

0.69	GO:2000707	positive regulation of dense core granule biogenesis
0.68	GO:0032762	mast cell cytokine production
0.68	GO:0002551	mast cell chemotaxis
0.67	GO:0033604	negative regulation of catecholamine secretion
0.65	GO:0002279	mast cell activation involved in immune response
0.65	GO:0002448	mast cell mediated immunity
0.64	GO:0043299	leukocyte degranulation
0.64	GO:0032418	lysosome localization
0.62	GO:0050830	defense response to Gram-positive bacterium
0.62	GO:0050829	defense response to Gram-negative bacterium

0.36	GO:0005509	calcium ion binding
0.34	GO:0005515	protein binding
0.32	GO:0004871	signal transducer activity
0.31	GO:0005198	structural molecule activity

0.81	GO:0030141	secretory granule
0.65	GO:0042629	mast cell granule
0.57	GO:0048471	perinuclear region of cytoplasm
0.43	GO:0030658	transport vesicle membrane
0.40	GO:0005576	extracellular region
0.34	GO:0005618	cell wall
0.32	GO:0005883	neurofilament
0.30	GO:0016021	integral component of membrane

sp|P05126|KPCB_BOVIN
Protein kinase C beta type
Search

PRKCB

0.92	Protein kinase C beta type

0.63	GO:0006468	protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.57	GO:0018210	peptidyl-threonine modification
0.56	GO:0045766	positive regulation of angiogenesis
0.55	GO:0050853	B cell receptor signaling pathway
0.55	GO:0050861	positive regulation of B cell receptor signaling pathway
0.55	GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway
0.54	GO:0010829	negative regulation of glucose transport
0.53	GO:0042113	B cell activation
0.53	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling

0.82	GO:0004697	protein kinase C activity
0.62	GO:0035403	histone kinase activity (H3-T6 specific)
0.62	GO:0008270	zinc ion binding
0.56	GO:0050681	androgen receptor binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.54	GO:0005080	protein kinase C binding

0.49	GO:0005829	cytosol
0.46	GO:0005654	nucleoplasm
0.43	GO:0005886	plasma membrane
0.40	GO:0005783	endoplasmic reticulum
0.38	GO:0070062	extracellular exosome
0.38	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0120038	plasma membrane bounded cell projection part
0.36	GO:0097733	photoreceptor cell cilium
0.35	GO:0031966	mitochondrial membrane
0.35	GO:0005903	brush border

0.82

EC:2.7.11.13

GO:0004697

sp|P05128|KPCG_BOVIN
Protein kinase C gamma type (Fragment)
Search

PRKCG

0.90	Protein kinase C gamma type

0.63	GO:0006468	protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.57	GO:0032425	positive regulation of mismatch repair
0.55	GO:0043278	response to morphine
0.55	GO:0032095	regulation of response to food
0.55	GO:0048265	response to pain
0.54	GO:0031397	negative regulation of protein ubiquitination
0.54	GO:1901799	negative regulation of proteasomal protein catabolic process
0.53	GO:0060384	innervation
0.53	GO:0042752	regulation of circadian rhythm

0.82	GO:0004697	protein kinase C activity
0.62	GO:0008270	zinc ion binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0008144	drug binding
0.51	GO:0004712	protein serine/threonine/tyrosine kinase activity
0.48	GO:0035403	histone kinase activity (H3-T6 specific)
0.42	GO:0009931	calcium-dependent protein serine/threonine kinase activity
0.41	GO:0019899	enzyme binding

0.52	GO:0030425	dendrite
0.51	GO:0014069	postsynaptic density
0.50	GO:0097060	synaptic membrane
0.49	GO:0030054	cell junction
0.45	GO:0005622	intracellular
0.43	GO:0043227	membrane-bounded organelle
0.40	GO:0012505	endomembrane system
0.36	GO:0001750	photoreceptor outer segment
0.36	GO:0043230	extracellular organelle
0.35	GO:0035866	alphav-beta3 integrin-PKCalpha complex

0.82

EC:2.7.11.13

GO:0004697

sp|P05131|KAPCB_BOVIN
cAMP-dependent protein kinase catalytic subunit beta
Search

PRKACB

0.91	cAMP-dependent protein kinase catalytic subunit alpha

0.61	GO:0006468	protein phosphorylation
0.59	GO:1901621	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
0.55	GO:0001843	neural tube closure
0.55	GO:0070613	regulation of protein processing
0.48	GO:0071374	cellular response to parathyroid hormone stimulus
0.48	GO:2000810	regulation of bicellular tight junction assembly
0.47	GO:0048240	sperm capacitation
0.47	GO:0071158	positive regulation of cell cycle arrest
0.47	GO:0034605	cellular response to heat
0.47	GO:0071333	cellular response to glucose stimulus

0.67	GO:0004674	protein serine/threonine kinase activity
0.53	GO:0031625	ubiquitin protein ligase binding
0.53	GO:0030554	adenyl nucleotide binding
0.52	GO:0097367	carbohydrate derivative binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0034237	protein kinase A regulatory subunit binding
0.48	GO:0060089	molecular transducer activity
0.46	GO:0000287	magnesium ion binding
0.45	GO:0004712	protein serine/threonine/tyrosine kinase activity

0.57	GO:0097546	ciliary base
0.56	GO:0045171	intercellular bridge
0.52	GO:0005813	centrosome
0.49	GO:0005829	cytosol
0.49	GO:0005952	cAMP-dependent protein kinase complex
0.48	GO:0036126	sperm flagellum
0.48	GO:0001669	acrosomal vesicle
0.48	GO:0048471	perinuclear region of cytoplasm
0.46	GO:0043197	dendritic spine
0.46	GO:0044853	plasma membrane raft

0.67

GO:0004674

sp|P05185|CP17A_BOVIN
Steroid 17-alpha-hydroxylase/17,20 lyase
Search

CYP17A1

0.93	steroid 17-alpha-hydroxylase/17,20 lyase precursor

0.71	GO:0006694	steroid biosynthetic process
0.67	GO:0042448	progesterone metabolic process
0.65	GO:0007548	sex differentiation
0.60	GO:0042446	hormone biosynthetic process
0.58	GO:0008211	glucocorticoid metabolic process
0.53	GO:0055114	oxidation-reduction process
0.41	GO:0042181	ketone biosynthetic process
0.37	GO:0008209	androgen metabolic process
0.36	GO:0018879	biphenyl metabolic process
0.36	GO:0018963	phthalate metabolic process

0.84	GO:0004508	steroid 17-alpha-monooxygenase activity
0.84	GO:0047442	17-alpha-hydroxyprogesterone aldolase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.46	GO:0047006	17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity
0.35	GO:0019825	oxygen binding

0.54	GO:0043025	neuronal cell body
0.53	GO:0030424	axon
0.44	GO:0005739	mitochondrion
0.35	GO:0005783	endoplasmic reticulum
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.84

EC:1.14.99.9

GO:0004508

sp|P05307|PDIA1_BOVIN
Protein disulfide-isomerase
Search

P4HB

0.48	Dolichyl-diphosphooligosaccharide--protein glycotransferase

0.68	GO:0045454	cell redox homeostasis
0.57	GO:1902175	regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
0.57	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline
0.56	GO:0046598	positive regulation of viral entry into host cell
0.53	GO:0034976	response to endoplasmic reticulum stress
0.53	GO:0071456	cellular response to hypoxia
0.42	GO:0006457	protein folding
0.41	GO:0055114	oxidation-reduction process
0.36	GO:0034378	chylomicron assembly
0.36	GO:0038155	interleukin-23-mediated signaling pathway

0.79	GO:0003756	protein disulfide isomerase activity
0.56	GO:0031545	peptidyl-proline 4-dioxygenase activity
0.54	GO:0019798	procollagen-proline dioxygenase activity
0.53	GO:0005178	integrin binding
0.52	GO:0015037	peptide disulfide oxidoreductase activity
0.51	GO:0046982	protein heterodimerization activity
0.37	GO:0019899	enzyme binding
0.34	GO:0003723	RNA binding
0.32	GO:0016740	transferase activity

0.69	GO:0005783	endoplasmic reticulum
0.53	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.52	GO:0009897	external side of plasma membrane
0.47	GO:1990204	oxidoreductase complex
0.43	GO:0044446	intracellular organelle part
0.43	GO:0042470	melanosome
0.43	GO:0043234	protein complex
0.40	GO:0043233	organelle lumen
0.37	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion

0.79

EC:5.3.4.1

GO:0003756

sp|P05363|NK2R_BOVIN
Substance-K receptor
Search

TACR2

0.97	Neuromedin-K receptor

0.85	GO:0007217	tachykinin receptor signaling pathway
0.64	GO:1902093	positive regulation of flagellated sperm motility
0.59	GO:0070472	regulation of uterine smooth muscle contraction
0.48	GO:0045987	positive regulation of smooth muscle contraction
0.43	GO:0007267	cell-cell signaling
0.42	GO:0033685	negative regulation of luteinizing hormone secretion
0.41	GO:0035106	operant conditioning
0.41	GO:0014057	positive regulation of acetylcholine secretion, neurotransmission
0.41	GO:0014827	intestine smooth muscle contraction
0.41	GO:0043117	positive regulation of vascular permeability

0.86	GO:0004995	tachykinin receptor activity
0.34	GO:0050254	rhodopsin kinase activity
0.34	GO:0005515	protein binding

0.62	GO:0097225	sperm midpiece
0.58	GO:0061827	sperm head
0.56	GO:0005886	plasma membrane
0.36	GO:0043025	neuronal cell body
0.36	GO:0030425	dendrite
0.36	GO:0031252	cell leading edge
0.34	GO:0005634	nucleus
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:2.7.11.14

GO:0050254

sp|P05402|PLRP1_BOVIN
Placental prolactin-related protein 1
Search

PRL

0.86	Chorionic somatomammotropin hormone 2

0.75	GO:0010469	regulation of receptor activity
0.46	GO:0045723	positive regulation of fatty acid biosynthetic process
0.45	GO:0030072	peptide hormone secretion
0.44	GO:0007595	lactation
0.43	GO:0010628	positive regulation of gene expression
0.43	GO:0043066	negative regulation of apoptotic process
0.41	GO:1903489	positive regulation of lactation
0.41	GO:0010751	negative regulation of nitric oxide mediated signal transduction
0.40	GO:0001825	blastocyst formation
0.40	GO:1902893	regulation of pri-miRNA transcription by RNA polymerase II

0.79	GO:0005179	hormone activity
0.48	GO:0005148	prolactin receptor binding
0.33	GO:0046872	metal ion binding

0.66	GO:0005576	extracellular region
0.35	GO:0005788	endoplasmic reticulum lumen
0.34	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

sp|P05630|ATPD_BOVIN
ATP synthase subunit delta, mitochondrial
Search

ATP5D

0.44	Mitochondrial ATP synthase subunit delta

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.69	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.35	GO:0042407	cristae formation
0.35	GO:0046688	response to copper ion
0.35	GO:0006839	mitochondrial transport
0.34	GO:0046907	intracellular transport
0.33	GO:0006119	oxidative phosphorylation
0.32	GO:0055114	oxidation-reduction process

0.72	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism
0.34	GO:0043531	ADP binding
0.34	GO:0032403	protein complex binding
0.34	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
0.33	GO:0005524	ATP binding

0.72	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)
0.53	GO:0005753	mitochondrial proton-transporting ATP synthase complex
0.34	GO:0005759	mitochondrial matrix

0.34

EC:1.1.1

GO:0016616

sp|P05631|ATPG_BOVIN
ATP synthase subunit gamma, mitochondrial
Search

ATP5C1

0.71	ATP synthase subunit gamma

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.69	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.35	GO:0042407	cristae formation
0.35	GO:0051457	maintenance of protein location in nucleus
0.34	GO:0043433	negative regulation of DNA binding transcription factor activity
0.34	GO:0006839	mitochondrial transport
0.34	GO:0006119	oxidative phosphorylation
0.34	GO:0000122	negative regulation of transcription by RNA polymerase II
0.33	GO:0046907	intracellular transport

0.71	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism
0.35	GO:0002039	p53 binding
0.34	GO:0046982	protein heterodimerization activity
0.34	GO:0003723	RNA binding

0.71	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)
0.51	GO:0005753	mitochondrial proton-transporting ATP synthase complex
0.51	GO:0043209	myelin sheath
0.36	GO:0070062	extracellular exosome
0.34	GO:0031974	membrane-enclosed lumen
0.34	GO:0090575	RNA polymerase II transcription factor complex
0.34	GO:0055029	nuclear DNA-directed RNA polymerase complex
0.30	GO:0016021	integral component of membrane

sp|P05632|ATP5E_BOVIN
ATP synthase subunit epsilon, mitochondrial
Search

ATP5E

0.88	ATP synthase subunit epsilonserine-threonine

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.69	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.38	GO:0042407	cristae formation
0.37	GO:0006839	mitochondrial transport
0.35	GO:0046907	intracellular transport

0.72	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism
0.37	GO:0008553	proton-exporting ATPase activity, phosphorylative mechanism

0.84	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)
0.36	GO:0005759	mitochondrial matrix

0.37

EC:3.6.3.6

GO:0008553

sp|P05689|CATZ_BOVIN
Cathepsin Z
Search

CTSZ

0.95	Cathepsin Z

0.61	GO:0006508	proteolysis
0.59	GO:0010757	negative regulation of plasminogen activation
0.57	GO:0060441	epithelial tube branching involved in lung morphogenesis
0.55	GO:0032091	negative regulation of protein binding
0.54	GO:1901214	regulation of neuron death
0.44	GO:0044257	cellular protein catabolic process
0.42	GO:0001525	angiogenesis
0.39	GO:2000179	positive regulation of neural precursor cell proliferation
0.39	GO:0010977	negative regulation of neuron projection development
0.38	GO:0043065	positive regulation of apoptotic process

0.72	GO:0008234	cysteine-type peptidase activity
0.50	GO:0004180	carboxypeptidase activity
0.42	GO:0004175	endopeptidase activity
0.33	GO:0005515	protein binding

0.55	GO:0005764	lysosome
0.54	GO:0099738	cell cortex region
0.52	GO:0005615	extracellular space
0.50	GO:0031410	cytoplasmic vesicle
0.49	GO:0005783	endoplasmic reticulum
0.39	GO:0030426	growth cone
0.38	GO:0009986	cell surface
0.36	GO:1903561	extracellular vesicle
0.35	GO:0031983	vesicle lumen
0.35	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane

0.72

GO:0008234

sp|P05785|K1C14_BOVIN
Keratin, type I cytoskeletal 14 (Fragment)
Search

0.71	Type I epidermal keratin mRNA, 3'end (Fragment)

0.61	GO:0042633	hair cycle
0.60	GO:0045104	intermediate filament cytoskeleton organization
0.56	GO:0030855	epithelial cell differentiation
0.54	GO:0007568	aging
0.51	GO:0043588	skin development
0.51	GO:0008544	epidermis development
0.51	GO:0097435	supramolecular fiber organization
0.49	GO:0002009	morphogenesis of an epithelium
0.47	GO:0051798	positive regulation of hair follicle development
0.46	GO:0051546	keratinocyte migration

0.62	GO:0005198	structural molecule activity
0.53	GO:1990254	keratin filament binding
0.50	GO:0032395	MHC class II receptor activity
0.48	GO:0042289	MHC class II protein binding

0.79	GO:0005882	intermediate filament
0.50	GO:0045178	basal part of cell
0.42	GO:0005634	nucleus
0.41	GO:0071944	cell periphery
0.39	GO:0070062	extracellular exosome
0.39	GO:0005737	cytoplasm
0.35	GO:0036338	viral membrane

sp|P05786|K2C8_BOVIN
Keratin, type II cytoskeletal 8
Search

KRT8

0.85	Keratin, type II cytoskeletal 8

0.45	GO:0097284	hepatocyte apoptotic process
0.44	GO:0033209	tumor necrosis factor-mediated signaling pathway
0.44	GO:0097191	extrinsic apoptotic signaling pathway
0.43	GO:0060706	cell differentiation involved in embryonic placenta development
0.40	GO:0043207	response to external biotic stimulus
0.39	GO:0051599	response to hydrostatic pressure
0.38	GO:0051704	multi-organism process
0.38	GO:0045214	sarcomere organization
0.35	GO:0070268	cornification
0.34	GO:0000904	cell morphogenesis involved in differentiation

0.62	GO:0005198	structural molecule activity
0.45	GO:0097110	scaffold protein binding
0.37	GO:0032403	protein complex binding
0.32	GO:0042626	ATPase activity, coupled to transmembrane movement of substances

0.82	GO:0045095	keratin filament
0.45	GO:0016327	apicolateral plasma membrane
0.44	GO:0042383	sarcolemma
0.44	GO:0030018	Z disc
0.42	GO:0005911	cell-cell junction
0.41	GO:0016363	nuclear matrix
0.39	GO:0043034	costamere
0.38	GO:0005654	nucleoplasm
0.38	GO:0016010	dystrophin-associated glycoprotein complex
0.36	GO:0070062	extracellular exosome

sp|P05805|CAC3_BOVIN
Proproteinase E
Search

0.86	Proproteinase E

0.61	GO:0006508	proteolysis
0.47	GO:0008203	cholesterol metabolic process
0.37	GO:0007586	digestion
0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.69	GO:0004252	serine-type endopeptidase activity
0.34	GO:0003700	DNA binding transcription factor activity

0.45	GO:0005615	extracellular space
0.34	GO:0005634	nucleus

0.69

GO:0004252

sp|P05980|PGFS1_BOVIN
Prostaglandin F synthase 1
Search

0.93	Dihydrodiol dehydrogenase 3

0.53	GO:0055114	oxidation-reduction process
0.46	GO:0044597	daunorubicin metabolic process
0.45	GO:0071395	cellular response to jasmonic acid stimulus
0.44	GO:0044598	doxorubicin metabolic process
0.43	GO:0008202	steroid metabolic process
0.42	GO:0071799	cellular response to prostaglandin D stimulus
0.41	GO:0006692	prostanoid metabolic process
0.41	GO:1900053	negative regulation of retinoic acid biosynthetic process
0.41	GO:0016488	farnesol catabolic process
0.41	GO:0042574	retinal metabolic process

0.54	GO:0016491	oxidoreductase activity
0.40	GO:0032052	bile acid binding
0.35	GO:0015125	bile acid transmembrane transporter activity
0.34	GO:0004452	isopentenyl-diphosphate delta-isomerase activity
0.33	GO:0005515	protein binding
0.32	GO:0016787	hydrolase activity

0.38	GO:0070062	extracellular exosome
0.37	GO:0005829	cytosol
0.36	GO:0005634	nucleus

0.54	EC:1	GO:0016491
0.34	KEGG:R01123	GO:0004452

sp|P06394|K1C10_BOVIN
Keratin, type I cytoskeletal 10
Search

0.83	Keratin 10 (Epidermolytic hyperkeratosis; keratosis palmaris et plantaris)

0.50	GO:0030216	keratinocyte differentiation
0.48	GO:0018149	peptide cross-linking
0.43	GO:0007010	cytoskeleton organization
0.41	GO:0045103	intermediate filament-based process
0.39	GO:0042633	hair cycle
0.38	GO:0097435	supramolecular fiber organization
0.37	GO:0012501	programmed cell death
0.37	GO:0007568	aging
0.36	GO:0071277	cellular response to calcium ion
0.36	GO:0002064	epithelial cell development

0.62	GO:0005198	structural molecule activity
0.37	GO:1990254	keratin filament binding
0.35	GO:0032395	MHC class II receptor activity
0.35	GO:0008092	cytoskeletal protein binding
0.35	GO:0097110	scaffold protein binding
0.35	GO:0042289	MHC class II protein binding

0.79	GO:0005882	intermediate filament
0.49	GO:0001533	cornified envelope
0.39	GO:0070062	extracellular exosome
0.37	GO:0005737	cytoplasm
0.36	GO:0005634	nucleus
0.36	GO:0045178	basal part of cell

sp|P06504|CRBS_BOVIN
Beta-crystallin S
Search

CRYGS

0.96	Crystallin gamma S

0.79	GO:0002088	lens development in camera-type eye
0.68	GO:0002009	morphogenesis of an epithelium
0.50	GO:0007601	visual perception
0.42	GO:0030855	epithelial cell differentiation
0.40	GO:0034614	cellular response to reactive oxygen species
0.36	GO:0048593	camera-type eye morphogenesis
0.36	GO:0006102	isocitrate metabolic process
0.35	GO:0000904	cell morphogenesis involved in differentiation
0.33	GO:0055114	oxidation-reduction process

0.82	GO:0005212	structural constituent of eye lens
0.36	GO:0005515	protein binding
0.35	GO:0004450	isocitrate dehydrogenase (NADP+) activity
0.34	GO:0051287	NAD binding
0.34	GO:0000287	magnesium ion binding

0.42	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm

0.35

GO:0004450

sp|P06526|TDT_BOVIN
DNA nucleotidylexotransferase
Search

DNTT

0.97	DNA nucleotidylexotransferase

0.63	GO:0071897	DNA biosynthetic process
0.41	GO:0006304	DNA modification
0.39	GO:0033198	response to ATP
0.38	GO:0006281	DNA repair

0.82	GO:0003912	DNA nucleotidylexotransferase activity
0.66	GO:0003887	DNA-directed DNA polymerase activity
0.52	GO:0003677	DNA binding
0.51	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding

0.58	GO:0005634	nucleus
0.50	GO:0005829	cytosol
0.49	GO:0031974	membrane-enclosed lumen
0.44	GO:0044446	intracellular organelle part
0.36	GO:0005694	chromosome

0.82

EC:2.7.7.31

GO:0003912

sp|P06579|TRBM_BOVIN
Thrombomodulin (Fragment)
Search

THBD

0.89	Thrombomodulin

0.81	GO:1900047	negative regulation of hemostasis
0.81	GO:0050819	negative regulation of coagulation
0.81	GO:0061045	negative regulation of wound healing
0.80	GO:0030193	regulation of blood coagulation
0.62	GO:0007565	female pregnancy
0.59	GO:0007165	signal transduction
0.47	GO:0007596	blood coagulation
0.46	GO:0010165	response to X-ray
0.45	GO:0051591	response to cAMP
0.44	GO:0032496	response to lipopolysaccharide

0.70	GO:0005509	calcium ion binding
0.68	GO:0004888	transmembrane signaling receptor activity
0.40	GO:0005201	extracellular matrix structural constituent
0.36	GO:0005515	protein binding
0.36	GO:0008061	chitin binding
0.35	GO:0004222	metalloendopeptidase activity
0.34	GO:0005044	scavenger receptor activity
0.34	GO:0008201	heparin binding
0.33	GO:0044877	macromolecular complex binding
0.33	GO:0008429	phosphatidylethanolamine binding

0.63	GO:0005887	integral component of plasma membrane
0.58	GO:0009986	cell surface
0.46	GO:0016327	apicolateral plasma membrane
0.44	GO:0044421	extracellular region part
0.42	GO:0005774	vacuolar membrane
0.34	GO:0005903	brush border
0.34	GO:0016324	apical plasma membrane
0.34	GO:0030139	endocytic vesicle
0.34	GO:0005905	clathrin-coated pit
0.34	GO:0099512	supramolecular fiber

0.35

GO:0004222

sp|P06623|CN37_BOVIN
2',3'-cyclic-nucleotide 3'-phosphodiesterase
Search

CNP

0.95	2',3'-cyclic-nucleotide 3'-phosphodiesterase

0.84	GO:0009214	cyclic nucleotide catabolic process
0.58	GO:0048709	oligodendrocyte differentiation
0.58	GO:0008344	adult locomotory behavior
0.56	GO:0061564	axon development
0.55	GO:0048667	cell morphogenesis involved in neuron differentiation
0.55	GO:0048812	neuron projection morphogenesis
0.49	GO:0009636	response to toxic substance
0.40	GO:0046902	regulation of mitochondrial membrane permeability
0.40	GO:0000226	microtubule cytoskeleton organization
0.40	GO:0032496	response to lipopolysaccharide

0.81	GO:0004113	2',3'-cyclic-nucleotide 3'-phosphodiesterase activity
0.48	GO:0003723	RNA binding
0.39	GO:0030551	cyclic nucleotide binding
0.34	GO:0003924	GTPase activity
0.34	GO:0005525	GTP binding
0.34	GO:0016301	kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding

0.65	GO:0042470	melanosome
0.57	GO:0043209	myelin sheath
0.52	GO:0005615	extracellular space
0.51	GO:0005654	nucleoplasm
0.50	GO:0005829	cytosol
0.41	GO:0031143	pseudopodium
0.40	GO:0005902	microvillus
0.39	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0005741	mitochondrial outer membrane
0.38	GO:0005874	microtubule

0.81

EC:3.1.4.37

GO:0004113

sp|P06624|MIP_BOVIN
Lens fiber major intrinsic protein
Search

MIP

0.97	Major intrinsic protein of eye lens fiber

0.65	GO:0006833	water transport
0.64	GO:1990349	gap junction-mediated intercellular transport
0.63	GO:0002088	lens development in camera-type eye
0.59	GO:0051289	protein homotetramerization
0.55	GO:0055085	transmembrane transport
0.54	GO:0045785	positive regulation of cell adhesion
0.54	GO:0007601	visual perception
0.41	GO:0006811	ion transport
0.38	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.38	GO:0071288	cellular response to mercury ion

0.69	GO:0022803	passive transmembrane transporter activity
0.66	GO:0005372	water transmembrane transporter activity
0.59	GO:0005212	structural constituent of eye lens
0.42	GO:0005516	calmodulin binding
0.37	GO:0015168	glycerol transmembrane transporter activity
0.35	GO:0046983	protein dimerization activity

0.51	GO:0005783	endoplasmic reticulum
0.51	GO:0016324	apical plasma membrane
0.45	GO:0005887	integral component of plasma membrane
0.44	GO:0005921	gap junction
0.38	GO:0009925	basal plasma membrane
0.38	GO:0016328	lateral plasma membrane
0.36	GO:0070062	extracellular exosome
0.35	GO:0055037	recycling endosome
0.33	GO:0009897	external side of plasma membrane

sp|P06642|HBE2_BOVIN
Hemoglobin subunit epsilon-2
Search

HBB

0.75	Hemoglobin subunit epsilon-M

0.79	GO:0015671	oxygen transport
0.40	GO:0070293	renal absorption
0.40	GO:0051291	protein heterooligomerization
0.39	GO:0042542	response to hydrogen peroxide
0.38	GO:0010942	positive regulation of cell death
0.38	GO:0042744	hydrogen peroxide catabolic process
0.37	GO:0098869	cellular oxidant detoxification
0.36	GO:0048821	erythrocyte development
0.36	GO:0010999	regulation of eIF2 alpha phosphorylation by heme
0.36	GO:0007596	blood coagulation

0.80	GO:0005344	oxygen carrier activity
0.79	GO:0019825	oxygen binding
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.42	GO:0031720	haptoglobin binding
0.41	GO:0030492	hemoglobin binding
0.38	GO:0004601	peroxidase activity

0.83	GO:0005833	hemoglobin complex
0.42	GO:0031838	haptoglobin-hemoglobin complex
0.40	GO:0005615	extracellular space
0.35	GO:0043209	myelin sheath
0.35	GO:1903561	extracellular vesicle
0.35	GO:0071682	endocytic vesicle lumen
0.34	GO:1904724	tertiary granule lumen
0.34	GO:1904813	ficolin-1-rich granule lumen
0.30	GO:0016020	membrane

0.38	EC:1.11.1.7	GO:0004601
0.38	KEGG:R03532	GO:0004601

sp|P06643|HBE4_BOVIN
Hemoglobin subunit epsilon-4
Search

0.76	A-gamma globin Osilo variant

0.79	GO:0015671	oxygen transport
0.38	GO:0007596	blood coagulation
0.36	GO:0000122	negative regulation of transcription by RNA polymerase II
0.36	GO:0048821	erythrocyte development
0.35	GO:0010999	regulation of eIF2 alpha phosphorylation by heme
0.35	GO:0070293	renal absorption
0.34	GO:0034109	homotypic cell-cell adhesion
0.34	GO:0045646	regulation of erythrocyte differentiation
0.34	GO:0051291	protein heterooligomerization
0.34	GO:0045639	positive regulation of myeloid cell differentiation

0.80	GO:0005344	oxygen carrier activity
0.79	GO:0019825	oxygen binding
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.35	GO:0031722	hemoglobin beta binding
0.35	GO:0031721	hemoglobin alpha binding
0.35	GO:0031720	haptoglobin binding
0.33	GO:0004601	peroxidase activity

0.83	GO:0005833	hemoglobin complex
0.40	GO:0072562	blood microparticle
0.35	GO:0031838	haptoglobin-hemoglobin complex
0.34	GO:0043209	myelin sheath
0.34	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.33	EC:1.11.1.7	GO:0004601
0.33	KEGG:R03532	GO:0004601

sp|P06833|PYY2_BOVIN
Caltrin
Search

PYY

0.77

Caltrin

0.75	GO:0010469	regulation of receptor activity
0.74	GO:0032098	regulation of appetite
0.72	GO:0007631	feeding behavior
0.72	GO:0007586	digestion
0.69	GO:0007218	neuropeptide signaling pathway
0.67	GO:0042742	defense response to bacterium
0.64	GO:0007267	cell-cell signaling

0.79	GO:0005179	hormone activity
0.69	GO:0001664	G-protein coupled receptor binding
0.68	GO:0005516	calmodulin binding

0.66

GO:0005576

extracellular region

sp|P06836|NEUM_BOVIN
Neuromodulin
Search

GAP43

0.92	Neuromodulin

0.78	GO:0040008	regulation of growth
0.58	GO:0016198	axon choice point recognition
0.58	GO:0051489	regulation of filopodium assembly
0.55	GO:0010001	glial cell differentiation
0.54	GO:0045165	cell fate commitment
0.42	GO:0042246	tissue regeneration
0.40	GO:0007339	binding of sperm to zona pellucida
0.39	GO:0031103	axon regeneration
0.36	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway

0.45	GO:0005516	calmodulin binding
0.41	GO:0035727	lysophosphatidic acid binding
0.40	GO:0001786	phosphatidylserine binding
0.38	GO:1901981	phosphatidylinositol phosphate binding

0.62	GO:0031527	filopodium membrane
0.57	GO:0014069	postsynaptic density
0.55	GO:0043005	neuron projection
0.46	GO:0030427	site of polarized growth
0.44	GO:0030054	cell junction
0.39	GO:0005737	cytoplasm
0.37	GO:0097060	synaptic membrane
0.35	GO:0043025	neuronal cell body
0.34	GO:0098793	presynapse

sp|P06868|PLMN_BOVIN
Plasminogen
Search

0.52	Plasminogen

0.69	GO:0042730	fibrinolysis
0.65	GO:0048771	tissue remodeling
0.64	GO:0007596	blood coagulation
0.60	GO:0006508	proteolysis
0.50	GO:0052213	interaction with symbiont via secreted substance involved in symbiotic interaction
0.49	GO:0071674	mononuclear cell migration
0.49	GO:0052212	modification of morphology or physiology of other organism via secreted substance involved in symbiotic interaction
0.49	GO:0045445	myoblast differentiation
0.49	GO:0046716	muscle cell cellular homeostasis
0.48	GO:0051919	positive regulation of fibrinolysis

0.68	GO:0004252	serine-type endopeptidase activity
0.49	GO:1904854	proteasome core complex binding
0.48	GO:0019900	kinase binding
0.48	GO:1990405	protein antigen binding
0.48	GO:0034185	apolipoprotein binding
0.44	GO:0019904	protein domain specific binding
0.43	GO:0051087	chaperone binding
0.43	GO:0005102	receptor binding
0.34	GO:0030545	receptor regulator activity
0.34	GO:0001968	fibronectin binding

0.54	GO:0005576	extracellular region
0.48	GO:0019897	extrinsic component of plasma membrane
0.45	GO:0009897	external side of plasma membrane
0.41	GO:0044218	other organism cell membrane
0.35	GO:0031093	platelet alpha granule lumen
0.33	GO:1990777	lipoprotein particle
0.33	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.68

GO:0004252

sp|P07033|ACYP2_BOVIN
Acylphosphatase-2
Search

ACYP2

0.50	Acylphosphatase

0.45	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.44	GO:0018108	peptidyl-tyrosine phosphorylation
0.34	GO:0046944	protein carbamoylation
0.34	GO:0051693	actin filament capping
0.33	GO:1901642	nucleoside transmembrane transport
0.33	GO:0007010	cytoskeleton organization
0.32	GO:0006261	DNA-dependent DNA replication
0.32	GO:0071897	DNA biosynthetic process
0.32	GO:0006281	DNA repair

0.80	GO:0003998	acylphosphatase activity
0.45	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.38	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0042802	identical protein binding
0.34	GO:0003725	double-stranded RNA binding
0.34	GO:0016743	carboxyl- or carbamoyltransferase activity
0.34	GO:0005200	structural constituent of cytoskeleton
0.34	GO:0005543	phospholipid binding

0.42	GO:0005739	mitochondrion
0.34	GO:0008091	spectrin
0.33	GO:0005887	integral component of plasma membrane

0.80

EC:3.6.1.7

GO:0003998

sp|P07106|ACBD5_BOVIN
Acyl-CoA-binding domain-containing protein 5
Search

ACBD5

0.96	Acyl-CoA-binding domain-containing protein 5

0.83	GO:0030242	autophagy of peroxisome
0.37	GO:0035973	aggrephagy
0.35	GO:0009062	fatty acid catabolic process
0.32	GO:0006508	proteolysis

0.81	GO:0000062	fatty-acyl-CoA binding
0.63	GO:0008289	lipid binding
0.33	GO:0004222	metalloendopeptidase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.52	GO:0005777	peroxisome
0.48	GO:0005654	nucleoplasm
0.40	GO:0031903	microbody membrane
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0004222

sp|P07107|ACBP_BOVIN
Acyl-CoA-binding protein
Search

DBI

0.61	Benzodiazepine receptor ligand

0.49	GO:0036151	phosphatidylcholine acyl-chain remodeling
0.37	GO:0021670	lateral ventricle development
0.37	GO:0001662	behavioral fear response
0.36	GO:0032228	regulation of synaptic transmission, GABAergic
0.36	GO:0018345	protein palmitoylation
0.36	GO:0060291	long-term synaptic potentiation
0.36	GO:0001942	hair follicle development
0.36	GO:0007611	learning or memory
0.36	GO:0006641	triglyceride metabolic process
0.35	GO:0030157	pancreatic juice secretion

0.82	GO:0000062	fatty-acyl-CoA binding
0.42	GO:0046983	protein dimerization activity
0.40	GO:0008289	lipid binding
0.37	GO:0030156	benzodiazepine receptor binding
0.33	GO:0008483	transaminase activity
0.33	GO:0030170	pyridoxal phosphate binding
0.32	GO:0016746	transferase activity, transferring acyl groups

0.40	GO:0005794	Golgi apparatus
0.40	GO:0005783	endoplasmic reticulum
0.37	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.36	GO:0008021	synaptic vesicle
0.34	GO:0043292	contractile fiber
0.34	GO:0044446	intracellular organelle part
0.34	GO:0005739	mitochondrion
0.33	GO:0043233	organelle lumen

0.33

EC:2.6.1

GO:0008483

sp|P07224|PROS_BOVIN
Vitamin K-dependent protein S
Search

PROS1

0.97	Vitamin K-dependent protein S

0.85	GO:0030195	negative regulation of blood coagulation
0.42	GO:0007596	blood coagulation
0.36	GO:0050766	positive regulation of phagocytosis
0.36	GO:0050900	leukocyte migration
0.36	GO:0048731	system development
0.36	GO:0002576	platelet degranulation
0.35	GO:0030449	regulation of complement activation
0.35	GO:0010951	negative regulation of endopeptidase activity
0.35	GO:0017187	peptidyl-glutamic acid carboxylation
0.35	GO:0032496	response to lipopolysaccharide

0.69	GO:0005509	calcium ion binding
0.35	GO:0004866	endopeptidase inhibitor activity
0.34	GO:0032403	protein complex binding
0.34	GO:0030296	protein tyrosine kinase activator activity
0.34	GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process
0.34	GO:0001786	phosphatidylserine binding
0.34	GO:0030971	receptor tyrosine kinase binding
0.34	GO:0005245	voltage-gated calcium channel activity
0.33	GO:0060090	molecular adaptor activity
0.33	GO:0048018	receptor ligand activity

0.65	GO:0005576	extracellular region
0.36	GO:0031093	platelet alpha granule lumen
0.36	GO:0005796	Golgi lumen
0.34	GO:0000139	Golgi membrane
0.34	GO:0005789	endoplasmic reticulum membrane
0.33	GO:0043234	protein complex
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P07318|CRBB1_BOVIN
Beta-crystallin B1
Search

CRYBB1

0.71	Acyl-CoA dehydrogenase, C-2 to C-3 short chain

0.75	GO:0007601	visual perception
0.36	GO:0006478	peptidyl-tyrosine sulfation
0.35	GO:0043010	camera-type eye development
0.32	GO:0055114	oxidation-reduction process

0.83	GO:0005212	structural constituent of eye lens
0.36	GO:0008476	protein-tyrosine sulfotransferase activity
0.35	GO:0005515	protein binding
0.34	GO:0003995	acyl-CoA dehydrogenase activity
0.33	GO:0050660	flavin adenine dinucleotide binding

0.30

GO:0031224

intrinsic component of membrane

0.36

EC:2.8.2.20

GO:0008476

sp|P07348|IFNA1_BOVIN
Interferon alpha-1
Search

0.89	Interferon alpha-D

0.78	GO:0051607	defense response to virus
0.76	GO:0010469	regulation of receptor activity
0.58	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein
0.58	GO:0002323	natural killer cell activation involved in immune response
0.57	GO:0042100	B cell proliferation
0.56	GO:0002286	T cell activation involved in immune response
0.56	GO:0043330	response to exogenous dsRNA
0.56	GO:0030183	B cell differentiation
0.55	GO:0002250	adaptive immune response
0.54	GO:0006959	humoral immune response

0.81	GO:0005125	cytokine activity
0.79	GO:0005126	cytokine receptor binding
0.51	GO:0032403	protein complex binding

0.73	GO:0005615	extracellular space
0.31	GO:0005622	intracellular

sp|P07352|IFNW1_BOVIN
Interferon omega-1
Search

0.94	Interferon alpha

0.78	GO:0051607	defense response to virus
0.76	GO:0010469	regulation of receptor activity
0.58	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein
0.58	GO:0002323	natural killer cell activation involved in immune response
0.57	GO:0042100	B cell proliferation
0.57	GO:0002286	T cell activation involved in immune response
0.56	GO:0043330	response to exogenous dsRNA
0.56	GO:0030183	B cell differentiation
0.55	GO:0002250	adaptive immune response
0.54	GO:0006959	humoral immune response

0.80	GO:0005125	cytokine activity
0.79	GO:0005126	cytokine receptor binding
0.51	GO:0032403	protein complex binding
0.45	GO:0005179	hormone activity

0.73	GO:0005615	extracellular space
0.30	GO:0016020	membrane

sp|P07353|IFNG_BOVIN
Interferon gamma
Search

IFNG

0.94	Interferon gamma

0.74	GO:0006955	immune response
0.71	GO:0040008	regulation of growth
0.71	GO:0051607	defense response to virus
0.69	GO:0010469	regulation of receptor activity
0.61	GO:0060552	positive regulation of fructose 1,6-bisphosphate metabolic process
0.61	GO:0060549	regulation of fructose 1,6-bisphosphate 1-phosphatase activity
0.61	GO:0032834	positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response
0.61	GO:2000309	positive regulation of tumor necrosis factor (ligand) superfamily member 11 production
0.60	GO:0060557	positive regulation of vitamin D biosynthetic process
0.60	GO:0032747	positive regulation of interleukin-23 production

0.86	GO:0005133	interferon-gamma receptor binding
0.73	GO:0005125	cytokine activity

0.68	GO:0005615	extracellular space
0.37	GO:0005622	intracellular
0.30	GO:0016020	membrane

sp|P07435|OBP_BOVIN
Odorant-binding protein
Search

0.46	Odorant-binding protein

0.47	GO:0007608	sensory perception of smell
0.40	GO:0050896	response to stimulus

0.51

GO:0036094

small molecule binding

0.44

GO:0005576

extracellular region

sp|P07455|IGF1_BOVIN
Insulin-like growth factor I
Search

IGF1

0.88	IGF-I splicing variant class 1

0.75	GO:0010469	regulation of receptor activity
0.59	GO:0045725	positive regulation of glycogen biosynthetic process
0.59	GO:0048009	insulin-like growth factor receptor signaling pathway
0.58	GO:0051050	positive regulation of transport
0.57	GO:0046324	regulation of glucose import
0.56	GO:1904073	regulation of trophectodermal cell proliferation
0.56	GO:2001234	negative regulation of apoptotic signaling pathway
0.55	GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development
0.55	GO:1905460	negative regulation of vascular associated smooth muscle cell apoptotic process
0.55	GO:0010560	positive regulation of glycoprotein biosynthetic process

0.79	GO:0005179	hormone activity
0.78	GO:0008083	growth factor activity
0.59	GO:0005159	insulin-like growth factor receptor binding
0.53	GO:0005158	insulin receptor binding
0.52	GO:0005178	integrin binding
0.35	GO:0043539	protein serine/threonine kinase activator activity
0.34	GO:0005496	steroid binding

0.73	GO:0005615	extracellular space
0.60	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex
0.55	GO:0036454	growth factor complex
0.46	GO:0070382	exocytic vesicle
0.40	GO:0005829	cytosol
0.37	GO:0031091	platelet alpha granule
0.35	GO:0005614	interstitial matrix
0.35	GO:0034774	secretory granule lumen
0.34	GO:0043025	neuronal cell body
0.30	GO:0031224	intrinsic component of membrane

sp|P07456|IGF2_BOVIN
Insulin-like growth factor II
Search

IGF2

0.94	Insulin like growth factor 2

0.75	GO:0010469	regulation of receptor activity
0.53	GO:0046628	positive regulation of insulin receptor signaling pathway
0.53	GO:0042104	positive regulation of activated T cell proliferation
0.51	GO:0051897	positive regulation of protein kinase B signaling
0.51	GO:0045840	positive regulation of mitotic nuclear division
0.49	GO:0043410	positive regulation of MAPK cascade
0.46	GO:0032868	response to insulin
0.44	GO:0060669	embryonic placenta morphogenesis
0.44	GO:0051781	positive regulation of cell division
0.43	GO:0051147	regulation of muscle cell differentiation

0.78	GO:0005179	hormone activity
0.77	GO:0008083	growth factor activity
0.53	GO:0005159	insulin-like growth factor receptor binding
0.52	GO:0005158	insulin receptor binding
0.38	GO:0043539	protein serine/threonine kinase activator activity
0.34	GO:0004511	tyrosine 3-monooxygenase activity
0.32	GO:0005506	iron ion binding

0.73	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.36	GO:0031093	platelet alpha granule lumen
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.34

EC:1.14.16.2

GO:0004511

sp|P07470|CX7A1_BOVIN
Cytochrome c oxidase subunit 7A1, mitochondrial
Search

0.97	Cytochrome c oxidase subunit VIIa polypeptide 1

0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0022900	electron transport chain
0.34	GO:0006879	cellular iron ion homeostasis
0.34	GO:0006826	iron ion transport
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity
0.34	GO:0008199	ferric iron binding
0.32	GO:0003676	nucleic acid binding

0.79	GO:0005746	mitochondrial respiratory chain
0.35	GO:0070062	extracellular exosome
0.35	GO:0045277	respiratory chain complex IV
0.30	GO:0016021	integral component of membrane

0.65

GO:0016676

sp|P07471|CX6A2_BOVIN
Cytochrome c oxidase subunit 6A2, mitochondrial
Search

COX6A2

0.81	Cytochrome c oxidase subunit 6A, mitochondrial

0.62	GO:1902600	hydrogen ion transmembrane transport
0.60	GO:0022900	electron transport chain
0.45	GO:0050790	regulation of catalytic activity
0.43	GO:0006119	oxidative phosphorylation
0.43	GO:0009060	aerobic respiration

0.64	GO:0015002	heme-copper terminal oxidase activity
0.64	GO:0016675	oxidoreductase activity, acting on a heme group of donors
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.61	GO:0009055	electron transfer activity
0.45	GO:0030234	enzyme regulator activity

0.84	GO:0005751	mitochondrial respiratory chain complex IV
0.36	GO:0043209	myelin sheath
0.30	GO:0031224	intrinsic component of membrane

0.64

GO:0016675

sp|P07501|ANF_BOVIN
Natriuretic peptides A
Search

NPPA

0.97	Atrial natriuretic peptide hormone

0.77	GO:0050880	regulation of blood vessel size
0.76	GO:0010469	regulation of receptor activity
0.67	GO:0007168	receptor guanylyl cyclase signaling pathway
0.66	GO:1903766	positive regulation of potassium ion export across plasma membrane
0.65	GO:1902261	positive regulation of delayed rectifier potassium channel activity
0.64	GO:0060372	regulation of atrial cardiac muscle cell membrane repolarization
0.64	GO:0060452	positive regulation of cardiac muscle contraction
0.63	GO:0010460	positive regulation of heart rate
0.62	GO:0006182	cGMP biosynthetic process
0.62	GO:0007565	female pregnancy

0.79	GO:0005179	hormone activity
0.62	GO:0071855	neuropeptide receptor binding
0.59	GO:0051427	hormone receptor binding

0.66	GO:0005576	extracellular region
0.46	GO:0043234	protein complex
0.41	GO:0042629	mast cell granule
0.39	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|P07507|MGP_BOVIN
Matrix Gla protein
Search

0.82	Matrix Gla protein (Fragment)

0.76	GO:0030500	regulation of bone mineralization
0.48	GO:0051216	cartilage development
0.48	GO:0001503	ossification
0.44	GO:0030154	cell differentiation
0.37	GO:0009653	anatomical structure morphogenesis
0.37	GO:0098743	cell aggregation
0.37	GO:0051384	response to glucocorticoid
0.37	GO:0051592	response to calcium ion
0.37	GO:0030324	lung development
0.37	GO:0009612	response to mechanical stimulus

0.70	GO:0005509	calcium ion binding
0.50	GO:0005201	extracellular matrix structural constituent
0.39	GO:0008147	structural constituent of bone
0.37	GO:0048306	calcium-dependent protein binding

0.74	GO:0031012	extracellular matrix
0.39	GO:0070062	extracellular exosome
0.35	GO:0005783	endoplasmic reticulum
0.34	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|P07514|NB5R3_BOVIN
NADH-cytochrome b5 reductase 3
Search

CYB5R3

0.64	NADH-cytochrome b5 reductase

0.52	GO:0055114	oxidation-reduction process
0.42	GO:0006695	cholesterol biosynthetic process
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0019852	L-ascorbic acid metabolic process
0.34	GO:0008015	blood circulation
0.34	GO:0006805	xenobiotic metabolic process

0.80	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H
0.37	GO:0016208	AMP binding
0.37	GO:0043531	ADP binding
0.37	GO:0050660	flavin adenine dinucleotide binding
0.36	GO:0051287	NAD binding
0.34	GO:0005515	protein binding

0.50	GO:0005811	lipid droplet
0.47	GO:0005783	endoplasmic reticulum
0.44	GO:0031966	mitochondrial membrane
0.43	GO:0019866	organelle inner membrane
0.40	GO:0031968	organelle outer membrane
0.39	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.38	GO:0031984	organelle subcompartment
0.36	GO:0070062	extracellular exosome
0.35	GO:0035578	azurophil granule lumen
0.35	GO:0005833	hemoglobin complex

0.80

EC:1.6.2.2

GO:0004128

sp|P07516|PPR1B_BOVIN
Protein phosphatase 1 regulatory subunit 1B
Search

PPP1R1B

0.97	Protein phosphatase 1 regulatory inhibitor subunit 1B

0.83	GO:0032515	negative regulation of phosphoprotein phosphatase activity
0.63	GO:0007621	negative regulation of female receptivity
0.62	GO:0043987	histone H3-S10 phosphorylation
0.62	GO:0043278	response to morphine
0.62	GO:0048148	behavioral response to cocaine
0.62	GO:0001975	response to amphetamine
0.61	GO:0008542	visual learning
0.61	GO:0007165	signal transduction
0.58	GO:0007626	locomotory behavior
0.49	GO:0006469	negative regulation of protein kinase activity

0.83	GO:0004864	protein phosphatase inhibitor activity
0.45	GO:0031751	D4 dopamine receptor binding
0.45	GO:0031749	D2 dopamine receptor binding
0.44	GO:0031750	D3 dopamine receptor binding
0.44	GO:0031752	D5 dopamine receptor binding
0.44	GO:0031748	D1 dopamine receptor binding
0.37	GO:0004862	cAMP-dependent protein kinase inhibitor activity
0.34	GO:0017127	cholesterol transporter activity
0.34	GO:0008289	lipid binding
0.34	GO:0043178	alcohol binding

0.58	GO:0043025	neuronal cell body
0.51	GO:0005829	cytosol
0.47	GO:0005634	nucleus
0.37	GO:0032839	dendrite cytoplasm
0.37	GO:1904115	axon cytoplasm
0.34	GO:0005770	late endosome
0.30	GO:0016020	membrane

sp|P07552|QCR10_BOVIN
Cytochrome b-c1 complex subunit 10
Search

0.96	Ubiquinol-cytochrome c reductase subunit

0.61	GO:0022900	electron transport chain
0.35	GO:0006119	oxidative phosphorylation
0.35	GO:0045333	cellular respiration

0.74	GO:0016681	oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor
0.62	GO:0009055	electron transfer activity
0.38	GO:0008327	methyl-CpG binding
0.35	GO:0046983	protein dimerization activity

0.50	GO:0031966	mitochondrial membrane
0.50	GO:0019866	organelle inner membrane
0.38	GO:0090545	CHD-type complex
0.38	GO:0070469	respiratory chain
0.38	GO:0090568	nuclear transcriptional repressor complex
0.37	GO:0000118	histone deacetylase complex
0.30	GO:0016021	integral component of membrane

0.74

GO:0016681

sp|P07589|FINC_BOVIN
Fibronectin
Search

0.43	Fibronectin

0.59	GO:1904237	positive regulation of substrate-dependent cell migration, cell attachment to substrate
0.58	GO:2001202	negative regulation of transforming growth factor-beta secretion
0.58	GO:0052047	interaction with other organism via secreted substance involved in symbiotic interaction
0.57	GO:0007161	calcium-independent cell-matrix adhesion
0.57	GO:0033622	integrin activation
0.55	GO:0048146	positive regulation of fibroblast proliferation
0.55	GO:0045773	positive regulation of axon extension
0.55	GO:0035987	endodermal cell differentiation
0.55	GO:0034446	substrate adhesion-dependent cell spreading
0.55	GO:0007044	cell-substrate junction assembly

0.56	GO:0097718	disordered domain specific binding
0.54	GO:0005178	integrin binding
0.54	GO:0002020	protease binding
0.53	GO:0016504	peptidase activator activity
0.53	GO:0008022	protein C-terminus binding
0.51	GO:0051087	chaperone binding
0.49	GO:0042802	identical protein binding
0.41	GO:0008201	heparin binding
0.36	GO:0045340	mercury ion binding
0.36	GO:0005201	extracellular matrix structural constituent

0.66	GO:0005576	extracellular region
0.53	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.52	GO:0016324	apical plasma membrane
0.48	GO:0031982	vesicle
0.43	GO:0043234	protein complex
0.34	GO:0005788	endoplasmic reticulum lumen

sp|P07688|CATB_BOVIN
Cathepsin B
Search

CTSB

0.82	Cathepsin B

0.68	GO:0050790	regulation of catalytic activity
0.61	GO:0006508	proteolysis
0.57	GO:0097067	cellular response to thyroid hormone stimulus
0.56	GO:0030574	collagen catabolic process
0.53	GO:0060429	epithelium development
0.53	GO:0046697	decidualization
0.50	GO:0044257	cellular protein catabolic process
0.48	GO:0030154	cell differentiation
0.46	GO:0051806	entry into cell of other organism involved in symbiotic interaction
0.46	GO:0044409	entry into host

0.74	GO:0004197	cysteine-type endopeptidase activity
0.55	GO:0043394	proteoglycan binding
0.53	GO:0005518	collagen binding
0.35	GO:0030984	kininogen binding
0.35	GO:0043621	protein self-association
0.34	GO:0042277	peptide binding
0.33	GO:0004252	serine-type endopeptidase activity

0.54	GO:0005764	lysosome
0.52	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0005615	extracellular space
0.49	GO:0005730	nucleolus
0.43	GO:0005739	mitochondrion
0.42	GO:0042470	melanosome
0.36	GO:1903561	extracellular vesicle
0.35	GO:0031904	endosome lumen
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0005775	vacuolar lumen

0.74

EC:3.4.22

GO:0004197

sp|P07857|NLTP_BOVIN
Non-specific lipid-transfer protein
Search

SCP2

0.60	Sterol carrier protein 2

0.61	GO:1901373	lipid hydroperoxide transport
0.60	GO:0032379	positive regulation of intracellular lipid transport
0.59	GO:0032380	regulation of intracellular sterol transport
0.58	GO:0032376	positive regulation of cholesterol transport
0.52	GO:0007031	peroxisome organization
0.45	GO:0015918	sterol transport
0.43	GO:0015914	phospholipid transport
0.43	GO:0006694	steroid biosynthetic process
0.39	GO:0032959	inositol trisphosphate biosynthetic process
0.39	GO:0042448	progesterone metabolic process

0.64	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
0.59	GO:0070538	oleic acid binding
0.59	GO:0036042	long-chain fatty acyl-CoA binding
0.55	GO:0032934	sterol binding
0.54	GO:0043178	alcohol binding
0.49	GO:0005102	receptor binding
0.46	GO:0015248	sterol transporter activity
0.39	GO:0008526	phosphatidylinositol transporter activity
0.37	GO:0005518	collagen binding
0.36	GO:1904121	phosphatidylethanolamine transporter activity

0.52	GO:0005777	peroxisome
0.48	GO:0005654	nucleoplasm
0.45	GO:0005739	mitochondrion
0.44	GO:0043234	protein complex
0.37	GO:0005615	extracellular space
0.37	GO:0031907	microbody lumen
0.36	GO:1903561	extracellular vesicle
0.36	GO:0031012	extracellular matrix
0.35	GO:0031312	extrinsic component of organelle membrane
0.34	GO:0031968	organelle outer membrane

0.64

EC:2.3.1

GO:0016747

sp|P07926|AT5G2_BOVIN
ATP synthase F(0) complex subunit C2, mitochondrial
Search

0.88	ATP synthase lipid-binding protein, mitochondrial

0.76	GO:0015991	ATP hydrolysis coupled proton transport
0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.38	GO:0045471	response to ethanol
0.36	GO:0042407	cristae formation
0.35	GO:0006839	mitochondrial transport
0.34	GO:0046907	intracellular transport
0.34	GO:0007568	aging
0.33	GO:0055114	oxidation-reduction process

0.71	GO:0008289	lipid binding
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.45	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
0.45	GO:0019829	cation-transporting ATPase activity
0.35	GO:0004450	isocitrate dehydrogenase (NADP+) activity
0.35	GO:0015662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
0.33	GO:0005515	protein binding

0.72	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)
0.48	GO:0005753	mitochondrial proton-transporting ATP synthase complex
0.34	GO:0005741	mitochondrial outer membrane
0.30	GO:0031224	intrinsic component of membrane

0.35

GO:0004450

sp|P07994|INHA_BOVIN
Inhibin alpha chain
Search

INHA

0.95	Inhibin alpha subunit

0.75	GO:0010469	regulation of receptor activity
0.71	GO:0042541	hemoglobin biosynthetic process
0.59	GO:0042127	regulation of cell proliferation
0.57	GO:0051726	regulation of cell cycle
0.53	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
0.53	GO:0060395	SMAD protein signal transduction
0.52	GO:0030509	BMP signaling pathway
0.50	GO:0043408	regulation of MAPK cascade
0.48	GO:0048468	cell development
0.48	GO:0042981	regulation of apoptotic process

0.78	GO:0008083	growth factor activity
0.73	GO:0005179	hormone activity
0.53	GO:0005160	transforming growth factor beta receptor binding
0.51	GO:0005125	cytokine activity
0.43	GO:0034711	inhibin binding
0.39	GO:0046982	protein heterodimerization activity

0.70	GO:0043512	inhibin A complex
0.69	GO:0034673	inhibin-betaglycan-ActRII complex
0.44	GO:0043513	inhibin B complex
0.42	GO:0001917	photoreceptor inner segment
0.41	GO:0001750	photoreceptor outer segment
0.41	GO:0043025	neuronal cell body
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|P07995|INHBA_BOVIN
Inhibin beta A chain
Search

INHBA

0.97	Inhibin beta-A-subunit

0.76	GO:0010469	regulation of receptor activity
0.65	GO:0042701	progesterone secretion
0.64	GO:0046880	regulation of follicle-stimulating hormone secretion
0.63	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
0.63	GO:0042541	hemoglobin biosynthetic process
0.62	GO:0060279	positive regulation of ovulation
0.62	GO:0032924	activin receptor signaling pathway
0.62	GO:0045648	positive regulation of erythrocyte differentiation
0.61	GO:0021773	striatal medium spiny neuron differentiation
0.61	GO:0061029	eyelid development in camera-type eye

0.78	GO:0008083	growth factor activity
0.73	GO:0005179	hormone activity
0.62	GO:0070699	type II activin receptor binding
0.58	GO:0017046	peptide hormone binding
0.58	GO:0005125	cytokine activity
0.52	GO:0042802	identical protein binding
0.48	GO:0005160	transforming growth factor beta receptor binding
0.43	GO:0034711	inhibin binding
0.39	GO:0046982	protein heterodimerization activity

0.66	GO:0005576	extracellular region
0.54	GO:0048471	perinuclear region of cytoplasm
0.46	GO:0043234	protein complex

sp|P08037|B4GT1_BOVIN
Beta-1,4-galactosyltransferase 1
Search

B4GALT1

0.89	UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 1

0.60	GO:0005975	carbohydrate metabolic process
0.58	GO:0060058	positive regulation of apoptotic process involved in mammary gland involution
0.57	GO:0007341	penetration of zona pellucida
0.57	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing
0.57	GO:0045136	development of secondary sexual characteristics
0.56	GO:0060046	regulation of acrosome reaction
0.56	GO:0060055	angiogenesis involved in wound healing
0.55	GO:0007339	binding of sperm to zona pellucida
0.55	GO:0002526	acute inflammatory response
0.54	GO:0048754	branching morphogenesis of an epithelial tube

0.65	GO:0016757	transferase activity, transferring glycosyl groups
0.49	GO:0030145	manganese ion binding
0.48	GO:0008092	cytoskeletal protein binding
0.37	GO:0042803	protein homodimerization activity

0.56	GO:0000138	Golgi trans cisterna
0.55	GO:0030057	desmosome
0.55	GO:0031526	brush border membrane
0.53	GO:0016323	basolateral plasma membrane
0.53	GO:0009897	external side of plasma membrane
0.49	GO:0005615	extracellular space
0.39	GO:0030175	filopodium
0.38	GO:0032580	Golgi cisterna membrane
0.36	GO:0035577	azurophil granule membrane
0.35	GO:1903561	extracellular vesicle

0.65

GO:0016757

sp|P08057|TNNI3_BOVIN
Troponin I, cardiac muscle
Search

TNNI3

0.90	High Mr cardiac troponin I

0.59	GO:0006941	striated muscle contraction
0.58	GO:0001980	regulation of systemic arterial blood pressure by ischemic conditions
0.57	GO:0060047	heart contraction
0.55	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling
0.54	GO:0055010	ventricular cardiac muscle tissue morphogenesis
0.54	GO:0001570	vasculogenesis
0.52	GO:0050881	musculoskeletal movement
0.52	GO:0006874	cellular calcium ion homeostasis
0.51	GO:0032780	negative regulation of ATPase activity
0.40	GO:0006940	regulation of smooth muscle contraction

0.59	GO:0031014	troponin T binding
0.56	GO:0030172	troponin C binding
0.55	GO:0019855	calcium channel inhibitor activity
0.54	GO:0048306	calcium-dependent protein binding
0.52	GO:0003779	actin binding
0.50	GO:0019901	protein kinase binding
0.49	GO:0019904	protein domain specific binding
0.49	GO:0032403	protein complex binding
0.38	GO:0046872	metal ion binding
0.33	GO:0016887	ATPase activity

0.82	GO:0005861	troponin complex
0.55	GO:0097512	cardiac myofibril
0.36	GO:0005634	nucleus
0.34	GO:0005829	cytosol

0.33

GO:0016887

sp|P08165|ADRO_BOVIN
NADPH:adrenodoxin oxidoreductase, mitochondrial
Search

FDXR

0.78	NADPH:adrenodoxin oxidoreductase, mitochondrial

0.52	GO:0055114	oxidation-reduction process
0.45	GO:0006744	ubiquinone biosynthetic process
0.41	GO:0008203	cholesterol metabolic process
0.37	GO:0006694	steroid biosynthetic process
0.36	GO:0008207	C21-steroid hormone metabolic process
0.36	GO:0006739	NADP metabolic process
0.35	GO:0042446	hormone biosynthetic process
0.33	GO:0006091	generation of precursor metabolites and energy

0.84	GO:0015039	NADPH-adrenodoxin reductase activity
0.37	GO:0004324	ferredoxin-NADP+ reductase activity
0.37	GO:0050661	NADP binding
0.35	GO:0005515	protein binding
0.34	GO:0043168	anion binding

0.72	GO:0005759	mitochondrial matrix
0.44	GO:0031966	mitochondrial membrane
0.44	GO:0019866	organelle inner membrane

0.84

EC:1.18.1.6

GO:0015039

sp|P08166|KAD2_BOVIN
Adenylate kinase 2, mitochondrial
Search

AK2

0.58	Adenylate kinase 2, mitochondrial

0.75	GO:0006172	ADP biosynthetic process
0.68	GO:0046939	nucleotide phosphorylation
0.63	GO:0046033	AMP metabolic process
0.54	GO:0046034	ATP metabolic process
0.44	GO:0060218	hematopoietic stem cell differentiation
0.42	GO:0002521	leukocyte differentiation
0.35	GO:0046060	dATP metabolic process
0.35	GO:0097066	response to thyroid hormone
0.35	GO:0015949	nucleobase-containing small molecule interconversion
0.35	GO:0035172	hemocyte proliferation

0.77	GO:0004017	adenylate kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.69	GO:0005758	mitochondrial intermembrane space
0.55	GO:0097226	sperm mitochondrial sheath
0.42	GO:0031966	mitochondrial membrane
0.42	GO:0019866	organelle inner membrane
0.38	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.33	GO:0005634	nucleus

0.77

EC:2.7.4.3

GO:0004017

sp|P08168|ARRS_BOVIN
S-arrestin
Search

SAG

0.97	S-antigen visual arrestin

0.61	GO:0007165	signal transduction
0.37	GO:0007601	visual perception
0.36	GO:0009416	response to light stimulus
0.36	GO:0022400	regulation of rhodopsin mediated signaling pathway
0.35	GO:0031399	regulation of protein modification process
0.35	GO:0019220	regulation of phosphate metabolic process
0.35	GO:0071478	cellular response to radiation
0.34	GO:0009582	detection of abiotic stimulus
0.34	GO:0009581	detection of external stimulus
0.34	GO:0051346	negative regulation of hydrolase activity

0.59	GO:0002046	opsin binding
0.55	GO:0051219	phosphoprotein binding
0.37	GO:0030507	spectrin binding
0.36	GO:0042802	identical protein binding
0.35	GO:0004864	protein phosphatase inhibitor activity
0.34	GO:0004143	diacylglycerol kinase activity
0.34	GO:0003951	NAD+ kinase activity
0.34	GO:0046982	protein heterodimerization activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding

0.57	GO:0001750	photoreceptor outer segment
0.56	GO:0001917	photoreceptor inner segment
0.35	GO:0005829	cytosol
0.33	GO:0045202	synapse
0.30	GO:0031224	intrinsic component of membrane

0.34	EC:2.7.1.107	GO:0004143
0.34	KEGG:R00104	GO:0003951

sp|P08169|MPRI_BOVIN
Cation-independent mannose-6-phosphate receptor
Search

IGF2R

0.82	Cation-independent mannose-6-phosphate receptor

0.84	GO:0007041	lysosomal transport
0.46	GO:0048009	insulin-like growth factor receptor signaling pathway
0.46	GO:0031100	animal organ regeneration
0.45	GO:0032526	response to retinoic acid
0.45	GO:0001889	liver development
0.44	GO:0007283	spermatogenesis
0.43	GO:0043065	positive regulation of apoptotic process
0.43	GO:0009791	post-embryonic development
0.41	GO:0007186	G-protein coupled receptor signaling pathway
0.40	GO:0043312	neutrophil degranulation

0.84	GO:0051219	phosphoprotein binding
0.65	GO:0004872	receptor activity
0.62	GO:0005520	insulin-like growth factor binding
0.61	GO:0005537	mannose binding
0.53	GO:0042802	identical protein binding
0.46	GO:0001972	retinoic acid binding
0.46	GO:0001965	G-protein alpha-subunit binding
0.43	GO:0004713	protein tyrosine kinase activity
0.41	GO:0019899	enzyme binding
0.39	GO:0004871	signal transducer activity

0.61	GO:0005641	nuclear envelope lumen
0.58	GO:0030140	trans-Golgi network transport vesicle
0.57	GO:0030139	endocytic vesicle
0.57	GO:0005770	late endosome
0.57	GO:0005769	early endosome
0.57	GO:0005802	trans-Golgi network
0.54	GO:0009986	cell surface
0.44	GO:0005925	focal adhesion
0.44	GO:0070062	extracellular exosome
0.43	GO:0048471	perinuclear region of cytoplasm

0.43

EC:2.7.10

GO:0004713

sp|P08209|CRGD_BOVIN
Gamma-crystallin D
Search

0.96	Gamma-crystallin D

0.75	GO:0002088	lens development in camera-type eye
0.63	GO:0007601	visual perception
0.62	GO:0030855	epithelial cell differentiation
0.58	GO:0048593	camera-type eye morphogenesis
0.55	GO:0000904	cell morphogenesis involved in differentiation
0.48	GO:0034614	cellular response to reactive oxygen species
0.42	GO:0043434	response to peptide hormone
0.36	GO:0006102	isocitrate metabolic process
0.33	GO:0055114	oxidation-reduction process

0.78	GO:0005212	structural constituent of eye lens
0.36	GO:0004450	isocitrate dehydrogenase (NADP+) activity
0.35	GO:0005515	protein binding
0.35	GO:0051287	NAD binding
0.34	GO:0000287	magnesium ion binding

0.55	GO:0005634	nucleus
0.45	GO:0005737	cytoplasm

0.36

GO:0004450

sp|P08219|GBRA1_BOVIN
Gamma-aminobutyric acid receptor subunit alpha-1
Search

GABRA1

0.97	Gamma-aminobutyric acid receptor subunit alpha-1

0.83	GO:0007214	gamma-aminobutyric acid signaling pathway
0.74	GO:0006821	chloride transport
0.60	GO:0034220	ion transmembrane transport
0.51	GO:0060078	regulation of postsynaptic membrane potential
0.40	GO:0071420	cellular response to histamine
0.40	GO:0051932	synaptic transmission, GABAergic
0.35	GO:0006836	neurotransmitter transport
0.34	GO:0001505	regulation of neurotransmitter levels

0.84	GO:0004890	GABA-A receptor activity
0.76	GO:0005230	extracellular ligand-gated ion channel activity
0.55	GO:0099095	ligand-gated anion channel activity
0.53	GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential
0.52	GO:0005254	chloride channel activity
0.51	GO:0022835	transmitter-gated channel activity
0.39	GO:0008503	benzodiazepine receptor activity
0.34	GO:0008144	drug binding
0.34	GO:0005515	protein binding

0.59	GO:1902711	GABA-A receptor complex
0.56	GO:0005886	plasma membrane
0.46	GO:0098794	postsynapse
0.45	GO:0060077	inhibitory synapse
0.43	GO:0043025	neuronal cell body
0.42	GO:0030425	dendrite
0.42	GO:0030424	axon
0.42	GO:0034707	chloride channel complex
0.40	GO:0030054	cell junction
0.40	GO:0030659	cytoplasmic vesicle membrane

sp|P08220|GBRB1_BOVIN
Gamma-aminobutyric acid receptor subunit beta-1
Search

GABRB1

0.87	Gamma-aminobutyric acid A receptor

0.61	GO:0007165	signal transduction
0.60	GO:0034220	ion transmembrane transport
0.52	GO:0006821	chloride transport
0.51	GO:0060384	innervation
0.50	GO:0090102	cochlea development
0.50	GO:0060119	inner ear receptor cell development
0.49	GO:0043524	negative regulation of neuron apoptotic process
0.48	GO:0007605	sensory perception of sound
0.48	GO:0071420	cellular response to histamine
0.41	GO:0032570	response to progesterone

0.84	GO:0004890	GABA-A receptor activity
0.76	GO:0005230	extracellular ligand-gated ion channel activity
0.56	GO:0099095	ligand-gated anion channel activity
0.53	GO:0005254	chloride channel activity
0.51	GO:0022835	transmitter-gated channel activity
0.41	GO:0050811	GABA receptor binding
0.37	GO:0042802	identical protein binding
0.32	GO:0003676	nucleic acid binding

0.61	GO:1902711	GABA-A receptor complex
0.56	GO:0005886	plasma membrane
0.42	GO:0098794	postsynapse
0.42	GO:0034707	chloride channel complex
0.40	GO:0030054	cell junction
0.39	GO:0030425	dendrite
0.38	GO:0005635	nuclear envelope
0.37	GO:0031410	cytoplasmic vesicle
0.37	GO:0012506	vesicle membrane
0.35	GO:0070062	extracellular exosome

sp|P08239|GNAO_BOVIN
Guanine nucleotide-binding protein G(o) subunit alpha
Search

GNAO1

0.78	Guanine nucleotide binding protein alpha O

0.79	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.44	GO:0007212	dopamine receptor signaling pathway
0.40	GO:0008016	regulation of heart contraction
0.40	GO:0007626	locomotory behavior
0.39	GO:0043278	response to morphine
0.39	GO:0051926	negative regulation of calcium ion transport
0.39	GO:0042542	response to hydrogen peroxide
0.38	GO:0030900	forebrain development
0.38	GO:0007568	aging
0.38	GO:0031175	neuron projection development

0.78	GO:0031683	G-protein beta/gamma-subunit complex binding
0.65	GO:0003924	GTPase activity
0.64	GO:0032550	purine ribonucleoside binding
0.63	GO:0019001	guanyl nucleotide binding
0.62	GO:0004871	signal transducer activity
0.52	GO:0032555	purine ribonucleotide binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0031852	mu-type opioid receptor binding
0.45	GO:0051430	corticotropin-releasing hormone receptor 1 binding
0.45	GO:0031821	G-protein coupled serotonin receptor binding

0.42	GO:1905360	GTPase complex
0.42	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.40	GO:0043209	myelin sheath
0.40	GO:0030425	dendrite
0.40	GO:0044297	cell body
0.38	GO:0098797	plasma membrane protein complex

sp|P08487|PLCG1_BOVIN
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
Search

PLCG1

0.52	Phosphoinositide phospholipase C

0.76	GO:0009395	phospholipid catabolic process
0.63	GO:0035556	intracellular signal transduction
0.56	GO:1901342	regulation of vasculature development
0.55	GO:0071364	cellular response to epidermal growth factor stimulus
0.55	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol
0.55	GO:0030334	regulation of cell migration
0.54	GO:0050852	T cell receptor signaling pathway
0.54	GO:0007173	epidermal growth factor receptor signaling pathway
0.52	GO:2000147	positive regulation of cell motility
0.50	GO:0016477	cell migration

0.82	GO:0004435	phosphatidylinositol phospholipase C activity
0.63	GO:0004871	signal transducer activity
0.62	GO:0005509	calcium ion binding
0.56	GO:0005168	neurotrophin TRKA receptor binding
0.55	GO:0035254	glutamate receptor binding
0.54	GO:0030971	receptor tyrosine kinase binding

0.53	GO:0001726	ruffle
0.52	GO:0030027	lamellipodium
0.52	GO:0008180	COP9 signalosome
0.50	GO:0005911	cell-cell junction
0.46	GO:0005829	cytosol
0.41	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.82	EC:3.1.4.11	GO:0004435
0.82	KEGG:R03435	GO:0004435

sp|P08728|K1C19_BOVIN
Keratin, type I cytoskeletal 19
Search

KRT19

0.87	Putative nuclear envelope protein lamin intermediate filament superfamily

0.54	GO:0043627	response to estrogen
0.53	GO:0045214	sarcomere organization
0.52	GO:0060706	cell differentiation involved in embryonic placenta development
0.51	GO:0007219	Notch signaling pathway
0.46	GO:0042633	hair cycle
0.45	GO:0045103	intermediate filament-based process
0.43	GO:0031424	keratinization
0.42	GO:0007568	aging
0.41	GO:0030336	negative regulation of cell migration
0.41	GO:0002009	morphogenesis of an epithelium

0.62	GO:0005198	structural molecule activity
0.42	GO:0032395	MHC class II receptor activity
0.41	GO:0042289	MHC class II protein binding
0.40	GO:0032403	protein complex binding
0.37	GO:0097110	scaffold protein binding
0.34	GO:0045294	alpha-catenin binding
0.34	GO:0045296	cadherin binding

0.79	GO:0005882	intermediate filament
0.55	GO:0043034	costamere
0.54	GO:1990357	terminal web
0.53	GO:0016327	apicolateral plasma membrane
0.52	GO:0042383	sarcolemma
0.52	GO:0030018	Z disc
0.40	GO:0070062	extracellular exosome
0.39	GO:0016010	dystrophin-associated glycoprotein complex
0.38	GO:0045178	basal part of cell
0.36	GO:0005634	nucleus

sp|P08760|KAD3_BOVIN
GTP:AMP phosphotransferase AK3, mitochondrial
Search

AK3

0.97	GTP:AMP phosphotransferase AK3, mitochondrial

0.79	GO:0046041	ITP metabolic process
0.76	GO:0006172	ADP biosynthetic process
0.69	GO:0046039	GTP metabolic process
0.68	GO:0046033	AMP metabolic process
0.65	GO:0046939	nucleotide phosphorylation
0.55	GO:0046051	UTP metabolic process
0.46	GO:0061515	myeloid cell development
0.36	GO:0046940	nucleoside monophosphate phosphorylation
0.36	GO:0046060	dATP metabolic process
0.36	GO:0021772	olfactory bulb development

0.80	GO:0046899	nucleoside triphosphate adenylate kinase activity
0.73	GO:0004017	adenylate kinase activity
0.60	GO:0032550	purine ribonucleoside binding
0.60	GO:0019001	guanyl nucleotide binding
0.52	GO:0032559	adenyl ribonucleotide binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005515	protein binding
0.34	GO:0004674	protein serine/threonine kinase activity
0.34	GO:0004550	nucleoside diphosphate kinase activity

0.69	GO:0005759	mitochondrial matrix
0.35	GO:0005758	mitochondrial intermembrane space

0.80

EC:2.7.4.10

GO:0046899

sp|P08814|PTMS_BOVIN
Parathymosin
Search

0.93	Prothymosin alpha

0.48	GO:0002376	immune system process
0.42	GO:0045905	positive regulation of translational termination
0.42	GO:0045901	positive regulation of translational elongation
0.42	GO:0006452	translational frameshifting
0.41	GO:0006325	chromatin organization
0.41	GO:0090304	nucleic acid metabolic process
0.41	GO:0006413	translational initiation
0.40	GO:0042254	ribosome biogenesis
0.39	GO:0043086	negative regulation of catalytic activity
0.39	GO:0036211	protein modification process

0.43	GO:0008135	translation factor activity, RNA binding
0.40	GO:0008270	zinc ion binding
0.40	GO:0004857	enzyme inhibitor activity
0.40	GO:0043022	ribosome binding
0.38	GO:0003684	damaged DNA binding
0.38	GO:0140096	catalytic activity, acting on a protein
0.38	GO:0033613	activating transcription factor binding
0.38	GO:0016772	transferase activity, transferring phosphorus-containing groups
0.37	GO:1901265	nucleoside phosphate binding
0.37	GO:0042393	histone binding

0.46	GO:0005634	nucleus
0.45	GO:0005829	cytosol
0.44	GO:0070013	intracellular organelle lumen
0.41	GO:0030684	preribosome
0.40	GO:0044446	intracellular organelle part
0.38	GO:0043232	intracellular non-membrane-bounded organelle
0.37	GO:0070062	extracellular exosome
0.37	GO:0043234	protein complex
0.36	GO:0048475	coated membrane
0.36	GO:0005732	small nucleolar ribonucleoprotein complex

0.38

EC:2.7

GO:0016772

sp|P08831|IL1A_BOVIN
Interleukin-1 alpha
Search

IL1A

0.83	Interleukin-1 alpha

0.86	GO:0001660	fever generation
0.83	GO:0051781	positive regulation of cell division
0.75	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.64	GO:0046688	response to copper ion
0.64	GO:0002248	connective tissue replacement involved in inflammatory response wound healing
0.64	GO:0045086	positive regulation of interleukin-2 biosynthetic process
0.64	GO:0034605	cellular response to heat
0.64	GO:2000391	positive regulation of neutrophil extravasation
0.63	GO:0071639	positive regulation of monocyte chemotactic protein-1 production

0.86	GO:0005149	interleukin-1 receptor binding
0.80	GO:0005125	cytokine activity
0.58	GO:0005507	copper ion binding

0.73	GO:0005615	extracellular space
0.68	GO:0005829	cytosol
0.35	GO:0009986	cell surface
0.33	GO:0005886	plasma membrane

sp|P08858|TKNK_BOVIN
Tachykinin-3
Search

TAC3

0.97	Neurokinin-B

0.85	GO:0007217	tachykinin receptor signaling pathway
0.46	GO:0007218	neuropeptide signaling pathway
0.40	GO:0007018	microtubule-based movement
0.38	GO:1902093	positive regulation of flagellated sperm motility
0.38	GO:0043278	response to morphine
0.38	GO:0045777	positive regulation of blood pressure
0.38	GO:0007565	female pregnancy

0.40	GO:0003777	microtubule motor activity
0.40	GO:0008017	microtubule binding
0.40	GO:0003779	actin binding
0.40	GO:0031836	neuromedin K receptor binding
0.39	GO:0031837	substance K receptor binding
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding

0.42	GO:0005576	extracellular region
0.40	GO:0016459	myosin complex
0.38	GO:0031982	vesicle
0.30	GO:0031224	intrinsic component of membrane

sp|P08904|RNAS6_BOVIN
Ribonuclease K6
Search

RNASE6

0.95	LOW QUALITY PROTEIN: ribonuclease K6

0.63	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.61	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.60	GO:0019731	antibacterial humoral response
0.59	GO:0050830	defense response to Gram-positive bacterium
0.58	GO:0050829	defense response to Gram-negative bacterium
0.56	GO:0045087	innate immune response
0.54	GO:0051607	defense response to virus
0.44	GO:0016070	RNA metabolic process
0.37	GO:0034655	nucleobase-containing compound catabolic process
0.37	GO:0044265	cellular macromolecule catabolic process

0.65	GO:0004519	endonuclease activity
0.53	GO:0004540	ribonuclease activity
0.51	GO:0003676	nucleic acid binding

0.57	GO:0005576	extracellular region
0.53	GO:0031410	cytoplasmic vesicle
0.40	GO:0005764	lysosome
0.30	GO:0016020	membrane

sp|P09428|IL1B_BOVIN
Interleukin-1 beta
Search

IL1B

0.46	Interleukin-1 beta

0.86	GO:0001660	fever generation
0.83	GO:0051781	positive regulation of cell division
0.76	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.58	GO:0035504	regulation of myosin light chain kinase activity
0.57	GO:0070487	monocyte aggregation
0.57	GO:0060559	positive regulation of calcidiol 1-monooxygenase activity
0.56	GO:0030730	sequestering of triglyceride
0.56	GO:0071639	positive regulation of monocyte chemotactic protein-1 production
0.56	GO:0045086	positive regulation of interleukin-2 biosynthetic process

0.86	GO:0005149	interleukin-1 receptor binding
0.81	GO:0005125	cytokine activity
0.50	GO:0019904	protein domain specific binding

0.83	GO:0005776	autophagosome
0.80	GO:0070062	extracellular exosome
0.78	GO:0005764	lysosome
0.71	GO:0031410	cytoplasmic vesicle
0.68	GO:0005829	cytosol
0.41	GO:0012505	endomembrane system
0.30	GO:0016020	membrane

sp|P09487|PPBT_BOVIN
Alkaline phosphatase, tissue-nonspecific isozyme
Search

ALPL

0.47	Alkaline phosphatase, tissue-nonspecific isozyme

0.68	GO:0016311	dephosphorylation
0.57	GO:0033280	response to vitamin D
0.56	GO:0001958	endochondral ossification
0.51	GO:0071407	cellular response to organic cyclic compound
0.51	GO:0003006	developmental process involved in reproduction
0.50	GO:0046677	response to antibiotic
0.44	GO:0009612	response to mechanical stimulus
0.42	GO:0071529	cementum mineralization
0.40	GO:0051384	response to glucocorticoid
0.39	GO:0032496	response to lipopolysaccharide

0.82	GO:0004035	alkaline phosphatase activity
0.43	GO:0016462	pyrophosphatase activity
0.35	GO:0046872	metal ion binding
0.35	GO:0002020	protease binding

0.58	GO:0065010	extracellular membrane-bounded organelle
0.51	GO:0005578	proteinaceous extracellular matrix
0.42	GO:0005886	plasma membrane
0.41	GO:0031225	anchored component of membrane
0.38	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.30	GO:0016021	integral component of membrane

0.82

EC:3.1.3.1

GO:0004035

sp|P09611|CSH1_BOVIN
Chorionic somatomammotropin hormone 1
Search

PRL

0.84	Chorionic somatomammotropin hormone

0.75	GO:0010469	regulation of receptor activity
0.51	GO:0045723	positive regulation of fatty acid biosynthetic process
0.50	GO:0030072	peptide hormone secretion
0.50	GO:0010628	positive regulation of gene expression
0.48	GO:1902893	regulation of pri-miRNA transcription by RNA polymerase II
0.48	GO:0001937	negative regulation of endothelial cell proliferation
0.48	GO:0046427	positive regulation of JAK-STAT cascade
0.47	GO:0007595	lactation
0.47	GO:0040014	regulation of multicellular organism growth
0.47	GO:0043066	negative regulation of apoptotic process

0.79	GO:0005179	hormone activity
0.59	GO:0005148	prolactin receptor binding
0.32	GO:0046872	metal ion binding

0.66	GO:0005576	extracellular region
0.37	GO:0031904	endosome lumen
0.36	GO:0005788	endoplasmic reticulum lumen
0.35	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|P09680|GIP_BOVIN
Gastric inhibitory polypeptide
Search

GIP

0.69	Gastric inhibitory polypeptide

0.76	GO:0010469	regulation of receptor activity
0.74	GO:0035640	exploration behavior
0.73	GO:0031018	endocrine pancreas development
0.72	GO:0019233	sensory perception of pain
0.71	GO:0007613	memory
0.71	GO:0008344	adult locomotory behavior
0.49	GO:0070094	positive regulation of glucagon secretion
0.48	GO:0010269	response to selenium ion
0.47	GO:0043950	positive regulation of cAMP-mediated signaling
0.46	GO:0048678	response to axon injury

0.79

GO:0005179

hormone activity

0.66	GO:0005576	extracellular region
0.44	GO:0043025	neuronal cell body
0.44	GO:0034774	secretory granule lumen
0.39	GO:0005788	endoplasmic reticulum lumen

sp|P09851|RASA1_BOVIN
Ras GTPase-activating protein 1
Search

RASA1

0.95	Ras GTPase-activating protein 1

0.83	GO:0046580	negative regulation of Ras protein signal transduction
0.74	GO:0043547	positive regulation of GTPase activity
0.60	GO:0007165	signal transduction
0.57	GO:0001953	negative regulation of cell-matrix adhesion
0.57	GO:0001568	blood vessel development
0.53	GO:0043066	negative regulation of apoptotic process
0.53	GO:0030833	regulation of actin filament polymerization
0.50	GO:0009653	anatomical structure morphogenesis
0.41	GO:1901215	negative regulation of neuron death
0.41	GO:0043523	regulation of neuron apoptotic process

0.75	GO:0005096	GTPase activator activity
0.56	GO:0001784	phosphotyrosine residue binding
0.50	GO:0051020	GTPase binding
0.50	GO:0005102	receptor binding
0.36	GO:0019870	potassium channel inhibitor activity
0.36	GO:0043422	protein kinase B binding
0.35	GO:1990782	protein tyrosine kinase binding
0.35	GO:0044325	ion channel binding
0.34	GO:0032403	protein complex binding
0.34	GO:0008134	transcription factor binding

0.53	GO:0001726	ruffle
0.48	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane
0.36	GO:0005737	cytoplasm
0.35	GO:0031965	nuclear membrane

sp|P09867|ROA1_BOVIN
Heterogeneous nuclear ribonucleoprotein A1
Search

HNRNPA1

0.88	Heterogeneous nuclear ribonucleoprotein A1

0.53	GO:1903936	cellular response to sodium arsenite
0.48	GO:0032211	negative regulation of telomere maintenance via telomerase
0.48	GO:0032212	positive regulation of telomere maintenance via telomerase
0.47	GO:0042149	cellular response to glucose starvation
0.47	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.45	GO:0051028	mRNA transport
0.44	GO:0008380	RNA splicing
0.44	GO:0051168	nuclear export
0.44	GO:0051170	nuclear import
0.43	GO:0006397	mRNA processing

0.59	GO:0003723	RNA binding
0.49	GO:0098505	G-rich strand telomeric DNA binding
0.44	GO:0019904	protein domain specific binding
0.38	GO:0042802	identical protein binding
0.38	GO:0036310	annealing helicase activity
0.36	GO:0008134	transcription factor binding

0.65	GO:0019013	viral nucleocapsid
0.58	GO:0030529	intracellular ribonucleoprotein complex
0.46	GO:0044428	nuclear part
0.44	GO:0031974	membrane-enclosed lumen
0.40	GO:1902494	catalytic complex
0.39	GO:0070062	extracellular exosome
0.38	GO:0030117	membrane coat
0.35	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|P0C0P5|NPS_BOVIN
Neuropeptide S
Search

NPS

0.97	Neuropeptide S

0.80	GO:0007218	neuropeptide signaling pathway
0.68	GO:0045760	positive regulation of action potential
0.67	GO:0032230	positive regulation of synaptic transmission, GABAergic
0.66	GO:0051968	positive regulation of synaptic transmission, glutamatergic
0.64	GO:0008542	visual learning
0.46	GO:0010841	positive regulation of circadian sleep/wake cycle, wakefulness

0.66	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

sp|P0C0S4|H2AZ_BOVIN
Histone H2A.Z
Search

sp|P0C0S9|H2A1_BOVIN
Histone H2A type 1
Search

0.10	Histone H2A type 1-D

0.54	GO:0006342	chromatin silencing
0.35	GO:0006334	nucleosome assembly

0.74	GO:0046982	protein heterodimerization activity
0.55	GO:0003677	DNA binding
0.36	GO:0019899	enzyme binding

0.74	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.47	GO:0031974	membrane-enclosed lumen
0.38	GO:0070062	extracellular exosome

sp|P0C0T1|ITPK1_BOVIN
Inositol-tetrakisphosphate 1-kinase
Search

ITPK1

0.77	Inositol-tetrakisphosphate 1-kinase b

0.85	GO:0032957	inositol trisphosphate metabolic process
0.57	GO:0016310	phosphorylation
0.55	GO:0021915	neural tube development
0.35	GO:0007596	blood coagulation
0.34	GO:0016311	dephosphorylation
0.33	GO:0007165	signal transduction

0.85	GO:0052726	inositol-1,3,4-trisphosphate 5-kinase activity
0.85	GO:0047325	inositol tetrakisphosphate 1-kinase activity
0.85	GO:0052725	inositol-1,3,4-trisphosphate 6-kinase activity
0.64	GO:0000287	magnesium ion binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0016853	isomerase activity
0.37	GO:0052831	inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity
0.37	GO:0052830	inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity

0.54	GO:0016324	apical plasma membrane
0.45	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

0.85	EC:2.7.1.159	GO:0052726
0.85	KEGG:R03428	GO:0052726

sp|P0C171|TIP39_BOVIN
Tuberoinfundibular peptide of 39 residues
Search

PTH2

0.97	Tuberoinfundibular peptide of 39 residues

0.80	GO:0007218	neuropeptide signaling pathway
0.43	GO:0006171	cAMP biosynthetic process
0.40	GO:0010469	regulation of receptor activity

0.41	GO:0005102	receptor binding
0.40	GO:0030545	receptor regulator activity

0.66	GO:0005576	extracellular region
0.30	GO:0016020	membrane

sp|P0C1G6|SWP70_BOVIN
Switch-associated protein 70
Search

SWAP70

0.91	Switch-associated protein 70

0.76	GO:0033633	negative regulation of cell-cell adhesion mediated by integrin
0.74	GO:1902309	negative regulation of peptidyl-serine dephosphorylation
0.73	GO:0060754	positive regulation of mast cell chemotaxis
0.72	GO:0002204	somatic recombination of immunoglobulin genes involved in immune response
0.70	GO:0002312	B cell activation involved in immune response
0.69	GO:0032233	positive regulation of actin filament bundle assembly
0.67	GO:0051017	actin filament bundle assembly
0.66	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.66	GO:0030835	negative regulation of actin filament depolymerization
0.61	GO:0032880	regulation of protein localization

0.66	GO:0045296	cadherin binding
0.56	GO:0005509	calcium ion binding
0.50	GO:0003677	DNA binding
0.47	GO:0032559	adenyl ribonucleotide binding
0.47	GO:0008144	drug binding
0.47	GO:0035639	purine ribonucleoside triphosphate binding

0.63	GO:0030027	lamellipodium
0.56	GO:0005634	nucleus
0.47	GO:0005856	cytoskeleton
0.46	GO:0005886	plasma membrane
0.45	GO:0005737	cytoplasm

sp|P0C1N9|PIGY_BOVIN
Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y
Search

PIGY

0.97	Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y

0.78

GO:0006506

GPI anchor biosynthetic process

0.59

GO:0016757

transferase activity, transferring glycosyl groups

0.86	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex
0.41	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.59

GO:0016757

sp|P0C2B6|RM51_BOVIN
39S ribosomal protein L51, mitochondrial
Search

MRPL51

0.97	Mitochondrial ribosomal protein L51

0.48	GO:0043043	peptide biosynthetic process
0.45	GO:0044267	cellular protein metabolic process
0.44	GO:0010467	gene expression
0.43	GO:0009059	macromolecule biosynthetic process
0.35	GO:0043624	cellular protein complex disassembly

0.64	GO:0003735	structural constituent of ribosome
0.34	GO:0005515	protein binding
0.32	GO:0016787	hydrolase activity

0.62	GO:0005762	mitochondrial large ribosomal subunit
0.35	GO:0031966	mitochondrial membrane
0.35	GO:0019866	organelle inner membrane

0.32

GO:0016787

sp|P0C2B7|RM52_BOVIN
39S ribosomal protein L52, mitochondrial
Search

MRPL52

0.95	Mitochondrial ribosomal protein L52

0.80	GO:0032543	mitochondrial translation
0.36	GO:0006415	translational termination
0.35	GO:0006414	translational elongation
0.34	GO:0006508	proteolysis

0.63	GO:0003735	structural constituent of ribosome
0.35	GO:0004222	metalloendopeptidase activity
0.35	GO:0008270	zinc ion binding

0.81	GO:0005762	mitochondrial large ribosomal subunit
0.36	GO:0031966	mitochondrial membrane
0.36	GO:0019866	organelle inner membrane
0.36	GO:0031012	extracellular matrix
0.30	GO:0016021	integral component of membrane

0.35

GO:0004222

sp|P0C2B8|RM55_BOVIN
39S ribosomal protein L55, mitochondrial
Search

MRPL55

0.97	Mitochondrial ribosomal protein L55

0.38	GO:0070126	mitochondrial translational termination
0.38	GO:0070125	mitochondrial translational elongation

0.64

GO:0003735

structural constituent of ribosome

0.82	GO:0005762	mitochondrial large ribosomal subunit
0.37	GO:0031966	mitochondrial membrane
0.37	GO:0019866	organelle inner membrane

sp|P0C2H4|DSE_BOVIN
Dermatan-sulfate epimerase
Search

DSE

0.97	Dermatan-sulfate epimerase

0.61	GO:0030208	dermatan sulfate biosynthetic process
0.40	GO:0030204	chondroitin sulfate metabolic process
0.39	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process
0.39	GO:0015012	heparan sulfate proteoglycan biosynthetic process

0.63	GO:0047757	chondroitin-glucuronate 5-epimerase activity
0.42	GO:0008146	sulfotransferase activity

0.50	GO:0005794	Golgi apparatus
0.50	GO:0005783	endoplasmic reticulum
0.49	GO:0005654	nucleoplasm
0.48	GO:0005829	cytosol
0.34	GO:0098588	bounding membrane of organelle
0.34	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.63

EC:5.1.3.19

GO:0047757

sp|P0C2W5|GBRB2_BOVIN
Gamma-aminobutyric acid receptor subunit beta-2 (Fragment)
Search

GABRB2

0.92	Gamma-aminobutyric acid A receptor

0.61	GO:0060384	innervation
0.61	GO:0090102	cochlea development
0.60	GO:0060119	inner ear receptor cell development
0.59	GO:0007165	signal transduction
0.59	GO:0043524	negative regulation of neuron apoptotic process
0.59	GO:0034220	ion transmembrane transport
0.57	GO:0007605	sensory perception of sound
0.50	GO:0071420	cellular response to histamine
0.45	GO:0006821	chloride transport
0.44	GO:0060021	palate development

0.81	GO:0004890	GABA-A receptor activity
0.73	GO:0005230	extracellular ligand-gated ion channel activity
0.45	GO:0005254	chloride channel activity
0.45	GO:0099095	ligand-gated anion channel activity
0.42	GO:0022835	transmitter-gated channel activity
0.41	GO:0042802	identical protein binding
0.35	GO:0035612	AP-2 adaptor complex binding

0.54	GO:0005886	plasma membrane
0.54	GO:1902711	GABA-A receptor complex
0.45	GO:0098794	postsynapse
0.42	GO:0034707	chloride channel complex
0.41	GO:0030054	cell junction
0.40	GO:0030659	cytoplasmic vesicle membrane
0.37	GO:0060077	inhibitory synapse
0.36	GO:0070062	extracellular exosome
0.36	GO:0005829	cytosol
0.35	GO:0043195	terminal bouton

sp|P0C591|DUPD1_BOVIN
Dual specificity phosphatase DUPD1
Search

DUPD1

0.97	Dual specificity phosphatase and pro isomerase domain containing 1

0.73	GO:0035335	peptidyl-tyrosine dephosphorylation
0.34	GO:1902310	positive regulation of peptidyl-serine dephosphorylation
0.34	GO:0044387	negative regulation of protein kinase activity by regulation of protein phosphorylation
0.33	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.33	GO:0000122	negative regulation of transcription by RNA polymerase II
0.33	GO:0043622	cortical microtubule organization
0.33	GO:0045785	positive regulation of cell adhesion
0.33	GO:0009737	response to abscisic acid
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:0010467	gene expression

0.78	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.73	GO:0004725	protein tyrosine phosphatase activity
0.51	GO:0042803	protein homodimerization activity
0.33	GO:0001102	RNA polymerase II activating transcription factor binding
0.33	GO:0002039	p53 binding
0.33	GO:0004647	phosphoserine phosphatase activity
0.33	GO:0003735	structural constituent of ribosome
0.32	GO:0016853	isomerase activity
0.32	GO:0016301	kinase activity

0.44	GO:0043234	protein complex
0.37	GO:0005737	cytoplasm
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.32	GO:0043232	intracellular non-membrane-bounded organelle
0.32	GO:0012505	endomembrane system
0.32	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.78

EC:3.1.3

GO:0008138

sp|P0C6R2|ARMC2_BOVIN
Armadillo repeat-containing protein 2
Search

ARMC2

0.97	Armadillo repeat-containing protein 2

0.40

GO:0055114

oxidation-reduction process

0.52	GO:0005515	protein binding
0.45	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors

0.45

EC:1.1

GO:0016614

sp|P0C6R3|EST4A_BOVIN
Carboxylesterase 4A
Search

0.42	Carboxylic ester hydrolase

0.36	GO:0051791	medium-chain fatty acid metabolic process
0.36	GO:0006695	cholesterol biosynthetic process
0.35	GO:0030855	epithelial cell differentiation
0.34	GO:0006581	acetylcholine catabolic process
0.34	GO:0006692	prostanoid metabolic process
0.33	GO:0010033	response to organic substance
0.33	GO:0050808	synapse organization
0.33	GO:0043413	macromolecule glycosylation
0.33	GO:0009101	glycoprotein biosynthetic process
0.33	GO:0007158	neuron cell-cell adhesion

0.57	GO:0004104	cholinesterase activity
0.36	GO:0004771	sterol esterase activity
0.34	GO:0102209	trans-permethrin hydrolase activity
0.34	GO:0003713	transcription coactivator activity
0.33	GO:0042043	neurexin family protein binding
0.32	GO:0042802	identical protein binding
0.32	GO:0004872	receptor activity

0.37	GO:0005576	extracellular region
0.36	GO:0005783	endoplasmic reticulum
0.34	GO:0031514	motile cilium
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part
0.33	GO:0045202	synapse
0.32	GO:0005634	nucleus
0.32	GO:0009986	cell surface
0.32	GO:0005887	integral component of plasma membrane
0.32	GO:0030054	cell junction

0.57

EC:3.1.1.8

GO:0004104

sp|P0C7I2|IGIP_BOVIN
IgA-inducing protein
Search

IGIP

0.70	IgA-inducing protein-like protein (Fragment)

0.56

GO:0005576

extracellular region

sp|P0C7Q4|GNAT3_BOVIN
Guanine nucleotide-binding protein G(t) subunit alpha-3
Search

GNAT3

0.97	Guanine nucleotide-binding protein Gt subunit alpha-X

0.82	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.62	GO:0050917	sensory perception of umami taste
0.60	GO:0050913	sensory perception of bitter taste
0.59	GO:0050908	detection of light stimulus involved in visual perception
0.57	GO:0050916	sensory perception of sweet taste
0.57	GO:0042462	eye photoreceptor cell development
0.56	GO:0060041	retina development in camera-type eye
0.54	GO:0007602	phototransduction
0.52	GO:0050912	detection of chemical stimulus involved in sensory perception of taste
0.51	GO:0048593	camera-type eye morphogenesis

0.81	GO:0031683	G-protein beta/gamma-subunit complex binding
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.64	GO:0004871	signal transducer activity
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0001664	G-protein coupled receptor binding
0.36	GO:0046872	metal ion binding
0.35	GO:0002046	opsin binding

0.62	GO:0001917	photoreceptor inner segment
0.61	GO:0001750	photoreceptor outer segment
0.50	GO:1905360	GTPase complex
0.49	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.46	GO:0043234	protein complex
0.46	GO:0032391	photoreceptor connecting cilium
0.40	GO:0098590	plasma membrane region
0.40	GO:0045177	apical part of cell
0.39	GO:0030141	secretory granule
0.38	GO:0097223	sperm part

sp|P0C7W1|TOR2X_BOVIN
Prosalusin
Search

TOR2A

0.97	Prosalusin

0.71	GO:0051085	chaperone cofactor-dependent protein refolding
0.64	GO:0072321	chaperone-mediated protein transport
0.62	GO:0045104	intermediate filament cytoskeleton organization
0.62	GO:0006998	nuclear envelope organization
0.61	GO:0048489	synaptic vesicle transport
0.58	GO:0031175	neuron projection development
0.56	GO:0051260	protein homooligomerization
0.54	GO:0007155	cell adhesion
0.42	GO:1900244	positive regulation of synaptic vesicle endocytosis
0.41	GO:0051940	regulation of catecholamine uptake involved in synaptic transmission

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008092	cytoskeletal protein binding
0.54	GO:0051082	unfolded protein binding
0.41	GO:0051787	misfolded protein binding
0.40	GO:0005179	hormone activity
0.36	GO:0016887	ATPase activity
0.35	GO:0005085	guanyl-nucleotide exchange factor activity

0.75	GO:0005788	endoplasmic reticulum lumen
0.56	GO:0005635	nuclear envelope
0.56	GO:0045202	synapse
0.41	GO:0042406	extrinsic component of endoplasmic reticulum membrane
0.39	GO:0070382	exocytic vesicle
0.38	GO:0097458	neuron part
0.37	GO:0005576	extracellular region
0.37	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.36

GO:0016887

sp|P0C8B3|CN142_BOVIN
Uncharacterized protein C14orf142 homolog
Search

GON7

0.97	GON7, KEOPS complex subunit homolog

0.84	GO:0000408	EKC/KEOPS complex
0.58	GO:0005634	nucleus

sp|P0C8S2|DRAXI_BOVIN
Draxin
Search

DRAXIN

0.97	Dorsal inhibitory axon guidance protein (Fragment)

0.81	GO:0007411	axon guidance
0.79	GO:0021528	commissural neuron differentiation in spinal cord
0.77	GO:0016055	Wnt signaling pathway
0.75	GO:0021516	dorsal spinal cord development
0.69	GO:0030900	forebrain development
0.67	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.60	GO:0030517	negative regulation of axon extension
0.58	GO:0043524	negative regulation of neuron apoptotic process

0.36

GO:0005515

protein binding

0.66

GO:0005576

extracellular region

sp|P0C8Z3|UBP22_BOVIN
Ubiquitin carboxyl-terminal hydrolase 22
Search

USP22

0.58	Ubiquitinyl hydrolase 1

0.73	GO:0016579	protein deubiquitination
0.70	GO:0006511	ubiquitin-dependent protein catabolic process
0.46	GO:0043967	histone H4 acetylation
0.46	GO:0016574	histone ubiquitination
0.46	GO:0045931	positive regulation of mitotic cell cycle
0.43	GO:0045893	positive regulation of transcription, DNA-templated
0.38	GO:0050821	protein stabilization
0.38	GO:0043065	positive regulation of apoptotic process

0.73	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.61	GO:0008270	zinc ion binding
0.48	GO:0010485	H4 histone acetyltransferase activity
0.47	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.43	GO:0019899	enzyme binding
0.39	GO:0061578	Lys63-specific deubiquitinase activity
0.39	GO:1990380	Lys48-specific deubiquitinase activity

0.45	GO:0016607	nuclear speck
0.45	GO:0000124	SAGA complex
0.30	GO:0031224	intrinsic component of membrane

0.73

EC:3.4.19.12

GO:0036459

sp|P0C914|OCC1_BOVIN
Overexpressed in colon carcinoma 1 protein homolog
Search

0.97	Overexpressed in colon carcinoma 1 protein homolog

sp|P0C920|CJ053_BOVIN
UPF0728 protein C10orf53 homolog
Search

sp|P0CB32|HS71L_BOVIN
Heat shock 70 kDa protein 1-like
Search

0.52	Epididymis secretory protein Li 103

0.52	GO:0007339	binding of sperm to zona pellucida
0.52	GO:0010638	positive regulation of organelle organization
0.52	GO:0042026	protein refolding
0.51	GO:1903749	positive regulation of establishment of protein localization to mitochondrion
0.51	GO:1903214	regulation of protein targeting to mitochondrion
0.50	GO:0090316	positive regulation of intracellular protein transport
0.47	GO:0010968	regulation of microtubule nucleation
0.46	GO:1901673	regulation of mitotic spindle assembly
0.44	GO:0032273	positive regulation of protein polymerization
0.43	GO:1902905	positive regulation of supramolecular fiber organization

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.50	GO:0031625	ubiquitin protein ligase binding
0.50	GO:0031072	heat shock protein binding
0.47	GO:0051082	unfolded protein binding
0.41	GO:0055131	C3HC4-type RING finger domain binding
0.40	GO:0031249	denatured protein binding
0.40	GO:0001106	RNA polymerase II transcription corepressor activity

0.54	GO:0002199	zona pellucida receptor complex
0.50	GO:0044297	cell body
0.50	GO:0008180	COP9 signalosome
0.46	GO:0005829	cytosol
0.43	GO:0005813	centrosome
0.40	GO:0072562	blood microparticle
0.39	GO:0016235	aggresome
0.39	GO:0070013	intracellular organelle lumen
0.39	GO:0005814	centriole
0.39	GO:0070062	extracellular exosome

0.35	EC:6.1.1.9	GO:0004832
0.35	KEGG:R03665	GO:0004832

sp|P0CG10|CTF8A_BOVIN
Chromosome transmission fidelity protein 8 homolog isoform 2
Search

0.63	Putative vesicle coat complex copii subunit sfb3

sp|P0CG11|CTF8_BOVIN
Chromosome transmission fidelity protein 8 homolog
Search

0.81	GO:0007064	mitotic sister chromatid cohesion
0.54	GO:1900264	positive regulation of DNA-directed DNA polymerase activity
0.37	GO:0006260	DNA replication
0.34	GO:0046856	phosphatidylinositol dephosphorylation
0.33	GO:0006367	transcription initiation from RNA polymerase II promoter
0.33	GO:0007264	small GTPase mediated signal transduction
0.33	GO:0006289	nucleotide-excision repair
0.33	GO:0032508	DNA duplex unwinding

0.51	GO:0003689	DNA clamp loader activity
0.51	GO:0043142	single-stranded DNA-dependent ATPase activity
0.34	GO:0034597	phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity
0.33	GO:0004003	ATP-dependent DNA helicase activity
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0003723	RNA binding
0.32	GO:0005515	protein binding
0.32	GO:0032559	adenyl ribonucleotide binding

0.83	GO:0031390	Ctf18 RFC-like complex
0.36	GO:0005634	nucleus
0.35	GO:0070062	extracellular exosome
0.34	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:3.1.3.66

GO:0034597

sp|P0CG25|EFCC1_BOVIN
EF-hand and coiled-coil domain-containing protein 1
Search

EFCC1

0.94	EF-hand and coiled-coil domain-containing protein 1

0.70

GO:0005509

calcium ion binding

sp|P0CG53|UBB_BOVIN
Polyubiquitin-B
Search

UBB

0.57	Polyubiquitin-B

0.60	GO:0021888	hypothalamus gonadotrophin-releasing hormone neuron development
0.59	GO:0060613	fat pad development
0.59	GO:0007144	female meiosis I
0.58	GO:0072520	seminiferous tubule development
0.58	GO:0097009	energy homeostasis
0.58	GO:0007141	male meiosis I
0.56	GO:0008585	female gonad development
0.52	GO:1902527	positive regulation of protein monoubiquitination
0.52	GO:1902255	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator
0.51	GO:0047497	mitochondrion transport along microtubule

0.47	GO:0004252	serine-type endopeptidase activity
0.45	GO:0004197	cysteine-type endopeptidase activity
0.45	GO:0070008	serine-type exopeptidase activity
0.44	GO:0003968	RNA-directed 5'-3' RNA polymerase activity
0.43	GO:0003735	structural constituent of ribosome
0.40	GO:0070035	purine NTP-dependent helicase activity
0.39	GO:0005515	protein binding
0.38	GO:0042623	ATPase activity, coupled
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding

0.55	GO:0043209	myelin sheath
0.48	GO:0043025	neuronal cell body
0.47	GO:0043229	intracellular organelle
0.47	GO:0043005	neuron projection
0.45	GO:0043227	membrane-bounded organelle
0.45	GO:0030529	intracellular ribonucleoprotein complex
0.45	GO:0044444	cytoplasmic part
0.44	GO:0043228	non-membrane-bounded organelle
0.38	GO:0019012	virion
0.30	GO:0016020	membrane

0.47

GO:0004252

sp|P0CH28|UBC_BOVIN
Polyubiquitin-C
Search

UBC

0.72	Polyubiquitin-C

0.50	GO:1901796	regulation of signal transduction by p53 class mediator
0.50	GO:0035635	entry of bacterium into host cell
0.49	GO:0019985	translesion synthesis
0.49	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.49	GO:0035666	TRIF-dependent toll-like receptor signaling pathway
0.49	GO:0006294	nucleotide-excision repair, preincision complex assembly
0.49	GO:0038128	ERBB2 signaling pathway
0.48	GO:1904380	endoplasmic reticulum mannose trimming
0.48	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.48	GO:0000717	nucleotide-excision repair, DNA duplex unwinding

0.46	GO:0002020	protease binding
0.42	GO:0003735	structural constituent of ribosome
0.39	GO:0003723	RNA binding

0.50	GO:0005634	nucleus
0.48	GO:0070062	extracellular exosome
0.48	GO:0043209	myelin sheath
0.48	GO:0044322	endoplasmic reticulum quality control compartment
0.46	GO:0030666	endocytic vesicle membrane
0.45	GO:0005840	ribosome
0.44	GO:0010008	endosome membrane
0.44	GO:0005741	mitochondrial outer membrane
0.43	GO:0070013	intracellular organelle lumen
0.42	GO:0005789	endoplasmic reticulum membrane

sp|P10036|PIT1_BOVIN
Pituitary-specific positive transcription factor 1
Search

POU1F1

0.95	Pituitary-specific positive transcription factor 1

0.69	GO:0045944	positive regulation of transcription by RNA polymerase II
0.62	GO:0060133	somatotropin secreting cell development
0.61	GO:0032962	positive regulation of inositol trisphosphate biosynthetic process
0.59	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway
0.58	GO:0040018	positive regulation of multicellular organism growth
0.57	GO:0030183	B cell differentiation
0.57	GO:0008340	determination of adult lifespan
0.57	GO:0001708	cell fate specification
0.54	GO:0051169	nuclear transport
0.54	GO:0008284	positive regulation of cell proliferation

0.67	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.60	GO:0043565	sequence-specific DNA binding
0.58	GO:0001105	RNA polymerase II transcription coactivator activity
0.58	GO:0001102	RNA polymerase II activating transcription factor binding
0.55	GO:0003714	transcription corepressor activity
0.55	GO:0044212	transcription regulatory region DNA binding
0.53	GO:0003682	chromatin binding
0.52	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.52	GO:0005667	transcription factor complex

sp|P10063|GBRA2_BOVIN
Gamma-aminobutyric acid receptor subunit alpha-2
Search

GABRA2

0.97	Gamma-aminobutyric acid receptor subunit alpha-2

0.85	GO:0007214	gamma-aminobutyric acid signaling pathway
0.77	GO:0006821	chloride transport
0.60	GO:0034220	ion transmembrane transport
0.43	GO:0060078	regulation of postsynaptic membrane potential
0.39	GO:0071420	cellular response to histamine
0.39	GO:0051932	synaptic transmission, GABAergic
0.37	GO:0006836	neurotransmitter transport
0.36	GO:0001505	regulation of neurotransmitter levels

0.84	GO:0004890	GABA-A receptor activity
0.76	GO:0005230	extracellular ligand-gated ion channel activity
0.47	GO:0099095	ligand-gated anion channel activity
0.45	GO:0005254	chloride channel activity
0.44	GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential
0.44	GO:0022835	transmitter-gated channel activity
0.41	GO:0008503	benzodiazepine receptor activity
0.34	GO:0008144	drug binding
0.34	GO:0005515	protein binding

0.56	GO:0005886	plasma membrane
0.54	GO:1902711	GABA-A receptor complex
0.54	GO:0060077	inhibitory synapse
0.51	GO:0098794	postsynapse
0.51	GO:0043025	neuronal cell body
0.50	GO:0030425	dendrite
0.50	GO:0030424	axon
0.41	GO:0034707	chloride channel complex
0.40	GO:0030659	cytoplasmic vesicle membrane
0.40	GO:0030054	cell junction

sp|P10064|GBRA3_BOVIN
Gamma-aminobutyric acid receptor subunit alpha-3
Search

GABRA3

0.97	Gamma-aminobutyric acid receptor subunit alpha-3

0.69	GO:0007214	gamma-aminobutyric acid signaling pathway
0.62	GO:0006821	chloride transport
0.60	GO:0034220	ion transmembrane transport
0.37	GO:0060384	innervation
0.37	GO:0001662	behavioral fear response
0.37	GO:0090102	cochlea development
0.37	GO:0060119	inner ear receptor cell development
0.37	GO:0008306	associative learning
0.37	GO:0043524	negative regulation of neuron apoptotic process
0.36	GO:0007605	sensory perception of sound

0.84	GO:0004890	GABA-A receptor activity
0.75	GO:0005230	extracellular ligand-gated ion channel activity
0.38	GO:0005254	chloride channel activity
0.36	GO:0008503	benzodiazepine receptor activity
0.34	GO:0005515	protein binding

0.55	GO:0005886	plasma membrane
0.49	GO:1902711	GABA-A receptor complex
0.39	GO:0034707	chloride channel complex
0.38	GO:0098794	postsynapse
0.38	GO:0030054	cell junction
0.36	GO:0030425	dendrite
0.36	GO:0044297	cell body
0.35	GO:0005654	nucleoplasm
0.35	GO:0005829	cytosol

sp|P10096|G3P_BOVIN
Glyceraldehyde-3-phosphate dehydrogenase
Search

GAPDH

0.52	Glyceraldehyde-3-phosphate dehydrogenase

0.67	GO:0006006	glucose metabolic process
0.66	GO:0006757	ATP generation from ADP
0.65	GO:0006090	pyruvate metabolic process
0.64	GO:0016052	carbohydrate catabolic process
0.64	GO:0019362	pyridine nucleotide metabolic process
0.52	GO:0055114	oxidation-reduction process
0.51	GO:0035606	peptidyl-cysteine S-trans-nitrosylation
0.48	GO:0051402	neuron apoptotic process
0.46	GO:0051873	killing by host of symbiont cells
0.46	GO:0050821	protein stabilization

0.78	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
0.66	GO:0050661	NADP binding
0.64	GO:0051287	NAD binding
0.51	GO:0035605	peptidyl-cysteine S-nitrosylase activity
0.46	GO:0019828	aspartic-type endopeptidase inhibitor activity
0.45	GO:0097718	disordered domain specific binding
0.44	GO:0008017	microtubule binding
0.41	GO:0042802	identical protein binding
0.35	GO:0019899	enzyme binding

0.53	GO:0097452	GAIT complex
0.45	GO:0005829	cytosol
0.44	GO:0005811	lipid droplet
0.43	GO:0015630	microtubule cytoskeleton
0.43	GO:0031965	nuclear membrane
0.38	GO:0030529	intracellular ribonucleoprotein complex
0.37	GO:0005886	plasma membrane
0.36	GO:0031012	extracellular matrix
0.36	GO:0043209	myelin sheath
0.36	GO:0070062	extracellular exosome

0.78

EC:1.2.1.12

GO:0004365

sp|P10103|HMGB1_BOVIN
High mobility group protein B1
Search

HMGB1

0.82	High mobility group box 1

0.57	GO:0032392	DNA geometric change
0.57	GO:0051103	DNA ligation involved in DNA repair
0.52	GO:0097350	neutrophil clearance
0.52	GO:0017055	negative regulation of RNA polymerase II transcriptional preinitiation complex assembly
0.51	GO:0002643	regulation of tolerance induction
0.51	GO:1990774	tumor necrosis factor secretion
0.51	GO:0032072	regulation of restriction endodeoxyribonuclease activity
0.51	GO:0050716	positive regulation of interleukin-1 secretion
0.51	GO:0035711	T-helper 1 cell activation
0.50	GO:0032425	positive regulation of mismatch repair

0.71	GO:0097100	supercoiled DNA binding
0.71	GO:0000405	bubble DNA binding
0.69	GO:0008301	DNA binding, bending
0.68	GO:0000400	four-way junction DNA binding
0.49	GO:0019958	C-X-C chemokine binding
0.49	GO:0001786	phosphatidylserine binding
0.49	GO:0070182	DNA polymerase binding
0.47	GO:0070491	repressing transcription factor binding
0.47	GO:0005178	integrin binding
0.46	GO:0001530	lipopolysaccharide binding

0.58	GO:0005634	nucleus
0.50	GO:0035868	alphav-beta3 integrin-HMGB1 complex
0.47	GO:0005694	chromosome
0.46	GO:0017053	transcriptional repressor complex
0.46	GO:0005768	endosome
0.45	GO:0005615	extracellular space
0.45	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.44	GO:0009986	cell surface
0.42	GO:0070013	intracellular organelle lumen
0.41	GO:0043005	neuron projection

0.40

EC:4

GO:0016829

sp|P10123|RLBP1_BOVIN
Retinaldehyde-binding protein 1
Search

RLBP1

0.94	Retinaldehyde-binding protein 1

0.78	GO:0007601	visual perception
0.50	GO:0007634	optokinetic behavior
0.40	GO:0007040	lysosome organization
0.36	GO:0006776	vitamin A metabolic process

0.86	GO:0016918	retinal binding
0.40	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding
0.39	GO:0019841	retinol binding

0.39	GO:0005802	trans-Golgi network
0.39	GO:0030136	clathrin-coated vesicle
0.39	GO:0044297	cell body
0.38	GO:0005768	endosome
0.34	GO:0005829	cytosol

sp|P10152|ANG1_BOVIN
Angiogenin-1
Search

ANG

0.97	Angiogenin ribonuclease 1

0.65	GO:0032431	activation of phospholipase A2 activity
0.64	GO:0006651	diacylglycerol biosynthetic process
0.63	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.63	GO:0007202	activation of phospholipase C activity
0.61	GO:0048662	negative regulation of smooth muscle cell proliferation
0.61	GO:0009303	rRNA transcription
0.61	GO:0001525	angiogenesis
0.61	GO:0001938	positive regulation of endothelial cell proliferation
0.59	GO:0050714	positive regulation of protein secretion
0.59	GO:0001666	response to hypoxia

0.65	GO:0004519	endonuclease activity
0.59	GO:0008201	heparin binding
0.57	GO:0004540	ribonuclease activity
0.55	GO:0042803	protein homodimerization activity
0.54	GO:0003779	actin binding
0.53	GO:0005102	receptor binding
0.53	GO:0005507	copper ion binding
0.51	GO:0003676	nucleic acid binding
0.47	GO:0042277	peptide binding

0.65	GO:0032311	angiogenin-PRI complex
0.62	GO:0005605	basal lamina
0.54	GO:0005615	extracellular space
0.53	GO:0031982	vesicle
0.53	GO:0005730	nucleolus
0.47	GO:0030426	growth cone
0.46	GO:0043025	neuronal cell body
0.43	GO:0044444	cytoplasmic part
0.40	GO:0043230	extracellular organelle
0.36	GO:0012505	endomembrane system

sp|P10175|COX8B_BOVIN
Cytochrome c oxidase subunit 8B, mitochondrial
Search

0.89	Cytochrome c oxidase, subunit VIIIb

0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0022900	electron transport chain
0.47	GO:0006119	oxidative phosphorylation
0.47	GO:0009060	aerobic respiration

0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity

0.57	GO:0005751	mitochondrial respiratory chain complex IV
0.30	GO:0031224	intrinsic component of membrane

0.65

GO:0016676

sp|P10279|PRIO_BOVIN
Major prion protein
Search

PRNP

0.85	Major prion protein 1

0.78	GO:0051260	protein homooligomerization
0.40	GO:1902938	regulation of intracellular calcium activated chloride channel activity
0.39	GO:0071280	cellular response to copper ion
0.39	GO:1904646	cellular response to amyloid-beta
0.39	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.39	GO:0043525	positive regulation of neuron apoptotic process
0.39	GO:0031648	protein destabilization
0.38	GO:0061098	positive regulation of protein tyrosine kinase activity
0.37	GO:1902951	negative regulation of dendritic spine maintenance
0.37	GO:0070885	negative regulation of calcineurin-NFAT signaling cascade

0.54	GO:0046872	metal ion binding
0.44	GO:0008017	microtubule binding
0.40	GO:0031802	type 5 metabotropic glutamate receptor binding
0.38	GO:0001540	amyloid-beta binding
0.37	GO:0032403	protein complex binding
0.37	GO:0042802	identical protein binding
0.36	GO:0002020	protease binding
0.35	GO:0005539	glycosaminoglycan binding
0.34	GO:0004872	receptor activity
0.34	GO:0004871	signal transducer activity

0.56	GO:0005886	plasma membrane
0.48	GO:0098857	membrane microdomain
0.47	GO:0031225	anchored component of membrane
0.44	GO:0005794	Golgi apparatus
0.39	GO:0106003	amyloid-beta complex
0.38	GO:0016234	inclusion body
0.38	GO:0030425	dendrite
0.38	GO:0031965	nuclear membrane
0.37	GO:0009986	cell surface
0.36	GO:0005829	cytosol

sp|P10462|S10A2_BOVIN
Protein S100-A2
Search

sp|P10522|MYP0_BOVIN
Myelin protein P0
Search

MPZ

0.97	Myelin protein zero

0.59	GO:0098743	cell aggregation
0.57	GO:0042552	myelination
0.54	GO:0098742	cell-cell adhesion via plasma-membrane adhesion molecules
0.45	GO:0023052	signaling
0.45	GO:0007154	cell communication
0.44	GO:0051716	cellular response to stimulus
0.42	GO:0065007	biological regulation
0.38	GO:0045217	cell-cell junction maintenance
0.35	GO:0060028	convergent extension involved in axis elongation

0.35	GO:0000062	fatty-acyl-CoA binding
0.34	GO:0005515	protein binding
0.34	GO:0005198	structural molecule activity

0.76	GO:0043209	myelin sheath
0.67	GO:0005887	integral component of plasma membrane
0.39	GO:0016323	basolateral plasma membrane
0.39	GO:0005791	rough endoplasmic reticulum
0.38	GO:0005764	lysosome
0.34	GO:0005925	focal adhesion
0.33	GO:0009986	cell surface

sp|P10568|MYO1A_BOVIN
Unconventional myosin-Ia
Search

MYO1A

0.85	LOW QUALITY PROTEIN: unconventional myosin-Ia

0.74	GO:0007018	microtubule-based movement
0.56	GO:0030033	microvillus assembly
0.52	GO:0007605	sensory perception of sound
0.51	GO:0051648	vesicle localization
0.48	GO:0006892	post-Golgi vesicle-mediated transport
0.46	GO:0007015	actin filament organization
0.45	GO:0030048	actin filament-based movement
0.39	GO:0007217	tachykinin receptor signaling pathway
0.36	GO:0033572	transferrin transport
0.35	GO:0045056	transcytosis

0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.74	GO:0003779	actin binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.55	GO:0032403	protein complex binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0000146	microfilament motor activity
0.48	GO:0045296	cadherin binding
0.45	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding

0.77	GO:0016459	myosin complex
0.59	GO:0005884	actin filament
0.57	GO:0005903	brush border
0.56	GO:0098858	actin-based cell projection
0.55	GO:0009925	basal plasma membrane
0.54	GO:0016328	lateral plasma membrane
0.53	GO:0044853	plasma membrane raft
0.52	GO:0045177	apical part of cell
0.52	GO:0030864	cortical actin cytoskeleton
0.50	GO:0032588	trans-Golgi network membrane

sp|P10575|GLRX1_BOVIN
Glutaredoxin-1
Search

GLRX

0.42	Thioltransferase

0.69	GO:0045454	cell redox homeostasis
0.61	GO:0022900	electron transport chain
0.55	GO:0045838	positive regulation of membrane potential
0.55	GO:2000651	positive regulation of sodium ion transmembrane transporter activity
0.41	GO:0080058	protein deglutathionylation
0.40	GO:0003147	neural crest cell migration involved in heart formation
0.39	GO:0046688	response to copper ion
0.39	GO:0055070	copper ion homeostasis
0.37	GO:0001944	vasculature development
0.37	GO:0007417	central nervous system development

0.72	GO:0015035	protein disulfide oxidoreductase activity
0.62	GO:0009055	electron transfer activity
0.52	GO:0047485	protein N-terminus binding
0.38	GO:0047139	glutathione-homocystine transhydrogenase activity
0.38	GO:0015038	glutathione disulfide oxidoreductase activity
0.37	GO:0016740	transferase activity
0.36	GO:0019153	protein-disulfide reductase (glutathione) activity
0.35	GO:0051117	ATPase binding
0.31	GO:0003676	nucleic acid binding

0.42	GO:0005634	nucleus
0.42	GO:0005739	mitochondrion
0.37	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.35	GO:0043025	neuronal cell body
0.35	GO:0030425	dendrite
0.34	GO:0031970	organelle envelope lumen
0.30	GO:0031224	intrinsic component of membrane

0.38

EC:1.8.4.1

GO:0047139

sp|P10730|ANPRC_BOVIN
Atrial natriuretic peptide receptor 3
Search

NPR3

0.94	Atrial natriuretic peptide clearance receptor

0.59	GO:0002158	osteoclast proliferation
0.58	GO:0035810	positive regulation of urine volume
0.57	GO:0033688	regulation of osteoblast proliferation
0.54	GO:0008217	regulation of blood pressure
0.53	GO:0001501	skeletal system development
0.46	GO:0007165	signal transduction
0.44	GO:0060038	cardiac muscle cell proliferation
0.41	GO:0030157	pancreatic juice secretion
0.41	GO:0051000	positive regulation of nitric-oxide synthase activity
0.40	GO:0007194	negative regulation of adenylate cyclase activity

0.62	GO:0016941	natriuretic peptide receptor activity
0.59	GO:0031404	chloride ion binding
0.58	GO:0017046	peptide hormone binding
0.52	GO:0042803	protein homodimerization activity
0.39	GO:0008528	G-protein coupled peptide receptor activity
0.36	GO:0004383	guanylate cyclase activity
0.34	GO:0004672	protein kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.44	GO:0043234	protein complex
0.37	GO:0070062	extracellular exosome
0.35	GO:0005887	integral component of plasma membrane
0.33	GO:0005622	intracellular

0.36

EC:4.6.1.2

GO:0004383

sp|P10731|AMD_BOVIN
Peptidyl-glycine alpha-amidating monooxygenase
Search

PAM

0.94	Peptidyl-glycine alpha-amidating monooxygenase

0.64	GO:0001519	peptide amidation
0.52	GO:0055114	oxidation-reduction process
0.42	GO:0018032	protein amidation
0.40	GO:0007595	lactation
0.40	GO:0060135	maternal process involved in female pregnancy
0.40	GO:0032355	response to estradiol
0.40	GO:0051384	response to glucocorticoid
0.40	GO:0042476	odontogenesis
0.40	GO:0022602	ovulation cycle process
0.39	GO:0009268	response to pH

0.82	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
0.69	GO:0005507	copper ion binding
0.64	GO:0004598	peptidylamidoglycolate lyase activity
0.47	GO:0008270	zinc ion binding
0.40	GO:0031418	L-ascorbic acid binding
0.38	GO:0019901	protein kinase binding
0.37	GO:0005509	calcium ion binding

0.41	GO:0030659	cytoplasmic vesicle membrane
0.40	GO:0043204	perikaryon
0.40	GO:0098805	whole membrane
0.39	GO:0098588	bounding membrane of organelle
0.39	GO:0030141	secretory granule
0.39	GO:0030133	transport vesicle
0.39	GO:0005802	trans-Golgi network
0.39	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0043005	neuron projection
0.38	GO:0009986	cell surface

0.82

EC:1.14.17

GO:0016715

sp|P10790|FABPH_BOVIN
Fatty acid-binding protein, heart
Search

FABP3

0.79	Fatty acid binding protein 3, muscle and heart (Mammary-derived growth inhibitor)

0.53	GO:0042632	cholesterol homeostasis
0.52	GO:2001245	regulation of phosphatidylcholine biosynthetic process
0.52	GO:0055091	phospholipid homeostasis
0.51	GO:0044539	long-chain fatty acid import
0.51	GO:0046320	regulation of fatty acid oxidation
0.44	GO:0032101	regulation of response to external stimulus
0.44	GO:0050872	white fat cell differentiation
0.44	GO:0071285	cellular response to lithium ion
0.43	GO:0050873	brown fat cell differentiation
0.43	GO:0001816	cytokine production

0.72	GO:0008289	lipid binding
0.52	GO:0033293	monocarboxylic acid binding
0.47	GO:0008092	cytoskeletal protein binding
0.39	GO:0005324	long-chain fatty acid transporter activity
0.35	GO:0043178	alcohol binding
0.32	GO:0097159	organic cyclic compound binding

0.48	GO:0005615	extracellular space
0.38	GO:0016528	sarcoplasm
0.38	GO:0043209	myelin sheath
0.37	GO:1903561	extracellular vesicle
0.36	GO:0005829	cytosol
0.36	GO:0043025	neuronal cell body
0.36	GO:0005911	cell-cell junction
0.35	GO:0042995	cell projection
0.34	GO:0031974	membrane-enclosed lumen
0.34	GO:0043231	intracellular membrane-bounded organelle

sp|P10861|UCP1_BOVIN
Mitochondrial brown fat uncoupling protein 1
Search

UCP1

0.88	Mitochondrial brown fat uncoupling protein 1

0.75	GO:0006839	mitochondrial transport
0.61	GO:1990845	adaptive thermogenesis
0.57	GO:0070542	response to fatty acid
0.56	GO:1903426	regulation of reactive oxygen species biosynthetic process
0.54	GO:0002021	response to dietary excess
0.53	GO:0071229	cellular response to acid chemical
0.53	GO:0050873	brown fat cell differentiation
0.53	GO:0009266	response to temperature stimulus
0.52	GO:0000302	response to reactive oxygen species
0.52	GO:0032870	cellular response to hormone stimulus

0.63	GO:0017077	oxidative phosphorylation uncoupler activity
0.58	GO:0036041	long-chain fatty acid binding
0.48	GO:1901612	cardiolipin binding
0.41	GO:0032555	purine ribonucleotide binding
0.35	GO:0032550	purine ribonucleoside binding
0.35	GO:0019001	guanyl nucleotide binding
0.34	GO:0005515	protein binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.60	GO:0031966	mitochondrial membrane
0.47	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P10881|LA_BOVIN
Lupus La protein homolog
Search

SSB

0.90	Sjogren syndrome antigen B

0.77	GO:0071045	nuclear histone mRNA catabolic process
0.74	GO:1903608	protein localization to cytoplasmic stress granule
0.73	GO:0075522	IRES-dependent viral translational initiation
0.72	GO:0071431	tRNA-containing ribonucleoprotein complex export from nucleus
0.71	GO:0051031	tRNA transport
0.70	GO:0097064	ncRNA export from nucleus
0.65	GO:0001682	tRNA 5'-leader removal
0.64	GO:0042780	tRNA 3'-end processing

0.73	GO:1990825	sequence-specific mRNA binding
0.70	GO:0008266	poly(U) RNA binding
0.57	GO:0000049	tRNA binding

0.61	GO:0005634	nucleus
0.61	GO:0030529	intracellular ribonucleoprotein complex
0.43	GO:0005737	cytoplasm

sp|P10894|PLCB1_BOVIN
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1
Search

PLCB1

0.52	Phosphoinositide phospholipase C

0.79	GO:0007420	brain development
0.72	GO:0051726	regulation of cell cycle
0.72	GO:0016042	lipid catabolic process
0.62	GO:0035556	intracellular signal transduction
0.57	GO:2000560	positive regulation of CD24 biosynthetic process
0.57	GO:2000438	negative regulation of monocyte extravasation
0.57	GO:0035723	interleukin-15-mediated signaling pathway
0.56	GO:0035722	interleukin-12-mediated signaling pathway
0.55	GO:2000344	positive regulation of acrosome reaction
0.55	GO:0048009	insulin-like growth factor receptor signaling pathway

0.81	GO:0004435	phosphatidylinositol phospholipase C activity
0.69	GO:0005509	calcium ion binding
0.63	GO:0004871	signal transducer activity
0.54	GO:0005521	lamin binding
0.53	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.51	GO:0005516	calmodulin binding
0.49	GO:0005096	GTPase activator activity
0.47	GO:0019899	enzyme binding

0.61	GO:0005634	nucleus
0.52	GO:0043209	myelin sheath
0.48	GO:0005737	cytoplasm
0.47	GO:0000785	chromatin
0.46	GO:0070013	intracellular organelle lumen

0.81	EC:3.1.4.11	GO:0004435
0.81	KEGG:R03435	GO:0004435

sp|P10895|PLCD1_BOVIN
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1
Search

PLCD1

0.52	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1

0.85	GO:0060716	labyrinthine layer blood vessel development
0.78	GO:0001525	angiogenesis
0.73	GO:0042127	regulation of cell proliferation
0.70	GO:0016042	lipid catabolic process
0.63	GO:0035556	intracellular signal transduction
0.62	GO:0034696	response to prostaglandin F
0.61	GO:0010701	positive regulation of norepinephrine secretion
0.60	GO:0032962	positive regulation of inositol trisphosphate biosynthetic process
0.58	GO:0010044	response to aluminum ion
0.58	GO:0055093	response to hyperoxia

0.85	GO:0032794	GTPase activating protein binding
0.85	GO:0070300	phosphatidic acid binding
0.84	GO:0001786	phosphatidylserine binding
0.82	GO:0004435	phosphatidylinositol phospholipase C activity
0.82	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.67	GO:0005509	calcium ion binding
0.62	GO:0004871	signal transducer activity
0.56	GO:0070679	inositol 1,4,5 trisphosphate binding
0.54	GO:0005544	calcium-dependent phospholipid binding

0.66	GO:0005829	cytosol
0.64	GO:0070062	extracellular exosome
0.54	GO:0045121	membrane raft
0.45	GO:0031966	mitochondrial membrane
0.45	GO:0005634	nucleus
0.42	GO:0005886	plasma membrane

0.82	EC:3.1.4.11	GO:0004435
0.82	KEGG:R03435	GO:0004435

sp|P10897|CY561_BOVIN
Cytochrome b561
Search

CYB561

0.88	Cytochrome b-561

0.58

GO:0022900

electron transport chain

0.84	GO:0000293	ferric-chelate reductase activity
0.37	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.48	GO:0005765	lysosomal membrane
0.40	GO:0044433	cytoplasmic vesicle part
0.40	GO:0030133	transport vesicle
0.39	GO:0012506	vesicle membrane
0.36	GO:0005770	late endosome
0.30	GO:0044425	membrane part

0.84

EC:1.16.1.7

GO:0000293

sp|P10938|PNMT_BOVIN
Phenylethanolamine N-methyltransferase
Search

PNMT

0.93	Phenylethanolamine N-methyltransferase

0.63	GO:0032259	methylation
0.45	GO:0042418	epinephrine biosynthetic process
0.38	GO:0010243	response to organonitrogen compound
0.37	GO:0031100	animal organ regeneration
0.37	GO:0035900	response to isolation stress
0.36	GO:0042493	response to drug
0.36	GO:0035902	response to immobilization stress
0.36	GO:0045472	response to ether
0.36	GO:0042415	norepinephrine metabolic process
0.36	GO:0009636	response to toxic substance

0.63	GO:0008168	methyltransferase activity
0.32	GO:0005515	protein binding

0.44	GO:0005829	cytosol
0.36	GO:0043196	varicosity
0.36	GO:0043204	perikaryon
0.36	GO:0043195	terminal bouton
0.35	GO:0030425	dendrite
0.33	GO:0005634	nucleus

0.63

GO:0008168

sp|P10948|RAB3B_BOVIN
Ras-related protein Rab-3B
Search

RAB3B

0.96	RAB3B, member RAS oncogene family

0.58	GO:0017157	regulation of exocytosis
0.57	GO:0051944	positive regulation of catecholamine uptake involved in synaptic transmission
0.56	GO:0097494	regulation of vesicle size
0.56	GO:0018125	peptidyl-cysteine methylation
0.56	GO:0051584	regulation of dopamine uptake involved in synaptic transmission
0.56	GO:0032226	positive regulation of synaptic transmission, dopaminergic
0.55	GO:0019882	antigen processing and presentation
0.54	GO:2001025	positive regulation of response to drug
0.51	GO:0043270	positive regulation of ion transport
0.37	GO:0015031	protein transport

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.62	GO:0031489	myosin V binding
0.61	GO:0030742	GTP-dependent protein binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0004871	signal transducer activity
0.32	GO:0046872	metal ion binding

0.58	GO:0008021	synaptic vesicle
0.56	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0030141	secretory granule
0.39	GO:0099501	exocytic vesicle membrane
0.38	GO:0031225	anchored component of membrane
0.37	GO:0031300	intrinsic component of organelle membrane
0.37	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.36	GO:0005886	plasma membrane
0.34	GO:1905360	GTPase complex

sp|P10949|RAB3C_BOVIN
Ras-related protein Rab-3C
Search

RAB3C

0.92	Putative rab subfamily protein of small gtpase (Fragment)

0.59	GO:0017157	regulation of exocytosis
0.54	GO:0061670	evoked neurotransmitter secretion
0.53	GO:0048790	maintenance of presynaptic active zone structure
0.52	GO:0003016	respiratory system process
0.52	GO:0050975	sensory perception of touch
0.52	GO:0051602	response to electrical stimulus
0.52	GO:0016188	synaptic vesicle maturation
0.52	GO:0048172	regulation of short-term neuronal synaptic plasticity
0.52	GO:1902803	regulation of synaptic vesicle transport
0.51	GO:0098693	regulation of synaptic vesicle cycle

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.63	GO:0031489	myosin V binding
0.63	GO:0030742	GTP-dependent protein binding
0.40	GO:0051021	GDP-dissociation inhibitor binding
0.39	GO:0051117	ATPase binding
0.39	GO:0008022	protein C-terminus binding
0.38	GO:0001671	ATPase activator activity
0.35	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.34	GO:0008168	methyltransferase activity

0.59	GO:0008021	synaptic vesicle
0.51	GO:0048471	perinuclear region of cytoplasm
0.50	GO:0043195	terminal bouton
0.50	GO:0001669	acrosomal vesicle
0.46	GO:0005768	endosome
0.39	GO:0099501	exocytic vesicle membrane
0.39	GO:0005829	cytosol
0.38	GO:0031225	anchored component of membrane
0.38	GO:0031300	intrinsic component of organelle membrane
0.36	GO:0005886	plasma membrane

0.35

GO:0004114

sp|P10950|ASMT_BOVIN
Acetylserotonin O-methyltransferase
Search

ASMT

0.93	Acetylserotonin O-methyltransferase

0.63	GO:0032259	methylation
0.54	GO:0030187	melatonin biosynthetic process
0.39	GO:2000019	negative regulation of male gonad development
0.36	GO:0043484	regulation of RNA splicing
0.34	GO:0046219	indolalkylamine biosynthetic process
0.33	GO:0043043	peptide biosynthetic process
0.33	GO:0044267	cellular protein metabolic process
0.33	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process

0.73	GO:0008171	O-methyltransferase activity
0.47	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity
0.46	GO:0047429	nucleoside-triphosphate diphosphatase activity
0.45	GO:0042803	protein homodimerization activity
0.36	GO:0051018	protein kinase A binding
0.34	GO:0008172	S-methyltransferase activity
0.33	GO:0003676	nucleic acid binding

0.37

GO:0005829

cytosol

0.73

GO:0008171

sp|P11017|GBB2_BOVIN
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
Search

GNB2

0.83	Guanine nucleotide-binding protein beta subunit

0.61	GO:0007165	signal transduction
0.50	GO:0060041	retina development in camera-type eye
0.49	GO:0050909	sensory perception of taste
0.49	GO:0008283	cell proliferation
0.41	GO:0010659	cardiac muscle cell apoptotic process
0.40	GO:0070208	protein heterotrimerization
0.39	GO:0071456	cellular response to hypoxia
0.39	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.37	GO:0071417	cellular response to organonitrogen compound
0.37	GO:0033762	response to glucagon

0.55	GO:0032403	protein complex binding
0.54	GO:0051020	GTPase binding
0.45	GO:0003924	GTPase activity
0.41	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity
0.40	GO:0031702	type 1 angiotensin receptor binding
0.40	GO:0004871	signal transducer activity
0.40	GO:0005246	calcium channel regulator activity
0.39	GO:0030507	spectrin binding

0.59	GO:0043209	myelin sheath
0.51	GO:1905360	GTPase complex
0.51	GO:0001750	photoreceptor outer segment
0.50	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.50	GO:0048471	perinuclear region of cytoplasm
0.45	GO:0098797	plasma membrane protein complex
0.42	GO:0044297	cell body
0.40	GO:0005765	lysosomal membrane
0.40	GO:0060170	ciliary membrane
0.39	GO:0001917	photoreceptor inner segment

0.41

GO:0047391

sp|P11019|VATE1_BOVIN
V-type proton ATPase subunit E 1
Search

ATP6V1E1

0.96	Vacuolar proton-ATPase E-subunit

0.76	GO:0015991	ATP hydrolysis coupled proton transport
0.45	GO:0060036	notochord cell vacuolation
0.45	GO:0033336	caudal fin development
0.44	GO:0031101	fin regeneration
0.42	GO:0060041	retina development in camera-type eye
0.35	GO:0090383	phagosome acidification
0.35	GO:0033572	transferrin transport
0.35	GO:0008286	insulin receptor signaling pathway
0.35	GO:0016241	regulation of macroautophagy

0.81	GO:0046961	proton-transporting ATPase activity, rotational mechanism
0.53	GO:0008553	proton-exporting ATPase activity, phosphorylative mechanism
0.47	GO:0051117	ATPase binding
0.44	GO:0008900	potassium:proton exchanging ATPase activity

0.72	GO:0033178	proton-transporting two-sector ATPase complex, catalytic domain
0.48	GO:0031410	cytoplasmic vesicle
0.47	GO:0005902	microvillus
0.47	GO:0016324	apical plasma membrane
0.46	GO:0012505	endomembrane system
0.45	GO:0097223	sperm part
0.43	GO:0005829	cytosol
0.40	GO:0005739	mitochondrion
0.37	GO:0005765	lysosomal membrane
0.36	GO:0070062	extracellular exosome

0.53

EC:3.6.3.6

GO:0008553

sp|P11023|RAB3A_BOVIN
Ras-related protein Rab-3A
Search

RAB3A

0.97	RAB3A, member RAS oncogene family

0.65	GO:0017157	regulation of exocytosis
0.61	GO:0061670	evoked neurotransmitter secretion
0.61	GO:0048790	maintenance of presynaptic active zone structure
0.59	GO:0048172	regulation of short-term neuronal synaptic plasticity
0.59	GO:0003016	respiratory system process
0.59	GO:0050975	sensory perception of touch
0.59	GO:0051602	response to electrical stimulus
0.59	GO:0016188	synaptic vesicle maturation
0.58	GO:1902803	regulation of synaptic vesicle transport
0.58	GO:0098693	regulation of synaptic vesicle cycle

0.69	GO:0031489	myosin V binding
0.69	GO:0030742	GTP-dependent protein binding
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0051021	GDP-dissociation inhibitor binding
0.36	GO:0051117	ATPase binding
0.36	GO:0008022	protein C-terminus binding

0.63	GO:0008021	synaptic vesicle
0.57	GO:0043195	terminal bouton
0.56	GO:0001669	acrosomal vesicle
0.52	GO:0005768	endosome
0.52	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0099501	exocytic vesicle membrane
0.36	GO:0005829	cytosol
0.36	GO:0031225	anchored component of membrane
0.35	GO:0031300	intrinsic component of organelle membrane
0.34	GO:0043234	protein complex

sp|P11024|NNTM_BOVIN
NAD(P) transhydrogenase, mitochondrial
Search

NNT

0.68	Nicotinamide nucleotide transhydrogenase

0.61	GO:0015992	proton transport
0.52	GO:0055114	oxidation-reduction process
0.48	GO:0072593	reactive oxygen species metabolic process
0.44	GO:0006739	NADP metabolic process
0.34	GO:0006101	citrate metabolic process
0.33	GO:0098662	inorganic cation transmembrane transport
0.33	GO:0006091	generation of precursor metabolites and energy

0.78	GO:0008746	NAD(P)+ transhydrogenase activity
0.49	GO:0050661	NADP binding
0.42	GO:0051287	NAD binding
0.33	GO:0015078	hydrogen ion transmembrane transporter activity

0.44	GO:0005739	mitochondrion
0.40	GO:0019866	organelle inner membrane
0.33	GO:0070469	respiratory chain
0.30	GO:0016021	integral component of membrane

0.78	EC:1.6.1	GO:0008746
0.78	KEGG:R00112	GO:0008746

sp|P11052|CSF2_BOVIN
Granulocyte-macrophage colony-stimulating factor
Search

CSF2

0.97	Granulocyte-macrophage colony-stimulating factor

0.76	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.68	GO:0045918	negative regulation of cytolysis
0.68	GO:0032747	positive regulation of interleukin-23 production
0.67	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus
0.67	GO:0010744	positive regulation of macrophage derived foam cell differentiation
0.67	GO:0071803	positive regulation of podosome assembly
0.66	GO:0043011	myeloid dendritic cell differentiation
0.66	GO:1901099	negative regulation of signal transduction in absence of ligand
0.65	GO:2001239	regulation of extrinsic apoptotic signaling pathway in absence of ligand

0.87	GO:0005129	granulocyte macrophage colony-stimulating factor receptor binding
0.78	GO:0008083	growth factor activity
0.64	GO:0005125	cytokine activity
0.36	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.36	GO:0004713	protein tyrosine kinase activity

0.66	GO:0005576	extracellular region
0.46	GO:0043227	membrane-bounded organelle
0.44	GO:0043229	intracellular organelle

0.36

EC:2.7.10

GO:0004713

sp|P11064|PPAC_BOVIN
Low molecular weight phosphotyrosine protein phosphatase
Search

ACP1

0.56	Low molecular weight phosphotyrosine protein phosphatase

0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.44	GO:0048793	pronephros development
0.34	GO:0098916	anterograde trans-synaptic signaling

0.85	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity
0.78	GO:0003993	acid phosphatase activity
0.34	GO:0017124	SH3 domain binding

0.51	GO:0042383	sarcolemma
0.49	GO:0009898	cytoplasmic side of plasma membrane
0.48	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.34	GO:0043005	neuron projection
0.30	GO:0016021	integral component of membrane

0.78

EC:3.1.3.2

GO:0003993

sp|P11116|LEG1_BOVIN
Galectin-1
Search

LGALS1

0.65

Galectin

0.55	GO:0046598	positive regulation of viral entry into host cell
0.55	GO:0002317	plasma cell differentiation
0.53	GO:0031295	T cell costimulation
0.53	GO:0045445	myoblast differentiation
0.43	GO:0006915	apoptotic process
0.40	GO:0034120	positive regulation of erythrocyte aggregation
0.40	GO:0035900	response to isolation stress
0.39	GO:0048678	response to axon injury
0.39	GO:0010812	negative regulation of cell-substrate adhesion
0.39	GO:0071333	cellular response to glucose stimulus

0.70	GO:0030246	carbohydrate binding
0.39	GO:0043236	laminin binding
0.37	GO:0042803	protein homodimerization activity
0.34	GO:0004871	signal transducer activity
0.34	GO:0003723	RNA binding
0.32	GO:0036094	small molecule binding

0.50	GO:0031012	extracellular matrix
0.48	GO:0005615	extracellular space
0.37	GO:0009986	cell surface
0.36	GO:1903561	extracellular vesicle
0.36	GO:0005622	intracellular
0.34	GO:0012505	endomembrane system
0.34	GO:0043233	organelle lumen

sp|P11151|LIPL_BOVIN
Lipoprotein lipase
Search

LPL

0.93	Lipoprotein lipase

0.70	GO:0016042	lipid catabolic process
0.61	GO:0009749	response to glucose
0.58	GO:0055096	low-density lipoprotein particle mediated signaling
0.57	GO:0010886	positive regulation of cholesterol storage
0.57	GO:0010890	positive regulation of sequestering of triglyceride
0.57	GO:0034372	very-low-density lipoprotein particle remodeling
0.57	GO:0090197	positive regulation of chemokine secretion
0.55	GO:0070328	triglyceride homeostasis
0.55	GO:0019432	triglyceride biosynthetic process
0.54	GO:0042632	cholesterol homeostasis

0.86	GO:0004465	lipoprotein lipase activity
0.80	GO:0008201	heparin binding
0.57	GO:0034185	apolipoprotein binding
0.49	GO:0005102	receptor binding
0.41	GO:0017129	triglyceride binding
0.36	GO:0004620	phospholipase activity

0.84	GO:0042627	chylomicron
0.84	GO:0034361	very-low-density lipoprotein particle
0.77	GO:0031225	anchored component of membrane
0.54	GO:0005886	plasma membrane
0.48	GO:0009986	cell surface
0.37	GO:0031012	extracellular matrix
0.36	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.86

EC:3.1.1.34

GO:0004465

sp|P11178|ODBA_BOVIN
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial
Search

BCKDHA

0.85	Branched chain keto acid dehydrogenase E1 alpha polypeptide

0.81	GO:0009083	branched-chain amino acid catabolic process
0.53	GO:0055114	oxidation-reduction process

0.83	GO:0003826	alpha-ketoacid dehydrogenase activity
0.83	GO:0003863	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity

0.83

EC:1.2.4.4

GO:0003863

sp|P11179|ODO2_BOVIN
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial
Search

DLST

0.68	Alpha-ketoglutarate dehydrogenase complex dihydrolipoyl succinyltransferase

0.70	GO:0006099	tricarboxylic acid cycle
0.60	GO:0018335	protein succinylation
0.42	GO:0070584	mitochondrion morphogenesis
0.42	GO:0006104	succinyl-CoA metabolic process
0.41	GO:0060047	heart contraction
0.40	GO:0006103	2-oxoglutarate metabolic process
0.40	GO:0030097	hemopoiesis
0.40	GO:0033512	L-lysine catabolic process to acetyl-CoA via saccharopine
0.38	GO:0006754	ATP biosynthetic process
0.35	GO:0006734	NADH metabolic process

0.80	GO:0016751	S-succinyltransferase activity
0.58	GO:0140096	catalytic activity, acting on a protein
0.34	GO:0031072	heat shock protein binding
0.34	GO:0051087	chaperone binding

0.79	GO:0045252	oxoglutarate dehydrogenase complex
0.54	GO:0043209	myelin sheath
0.45	GO:0005739	mitochondrion
0.45	GO:0005634	nucleus
0.36	GO:0070062	extracellular exosome
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.80

EC:2.3.1

GO:0016751

sp|P11180|ODP2_BOVIN
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex (Fragment)
Search

0.10	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex (Fragment)

0.30	GO:0072350	tricarboxylic acid metabolic process
0.30	GO:0009060	aerobic respiration
0.30	GO:0005996	monosaccharide metabolic process

0.30	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
0.30	GO:0140096	catalytic activity, acting on a protein

0.30	GO:0044429	mitochondrial part
0.30	GO:0031974	membrane-enclosed lumen

0.30

EC:2.3.1

GO:0016747

sp|P11181|ODB2_BOVIN
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial
Search

DBT

0.44	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex

0.41

GO:0009081

branched-chain amino acid metabolic process

0.62	GO:0016746	transferase activity, transferring acyl groups
0.51	GO:0031625	ubiquitin protein ligase binding

0.52

GO:0042645

mitochondrial nucleoid

0.62

EC:2.3

GO:0016746

sp|P11242|GALA_BOVIN
Galanin peptides
Search

GAL

0.97	Galanin and GMAP prepropeptide

0.76	GO:0010469	regulation of receptor activity
0.63	GO:1902891	negative regulation of root hair elongation
0.62	GO:1902608	positive regulation of large conductance calcium-activated potassium channel activity
0.62	GO:0051795	positive regulation of timing of catagen
0.61	GO:0051464	positive regulation of cortisol secretion
0.60	GO:0010737	protein kinase A signaling
0.58	GO:0007218	neuropeptide signaling pathway
0.57	GO:0019933	cAMP-mediated signaling
0.54	GO:0045944	positive regulation of transcription by RNA polymerase II
0.52	GO:0007399	nervous system development

0.79	GO:0005179	hormone activity
0.66	GO:0031763	galanin receptor binding
0.62	GO:0004966	galanin receptor activity

0.66	GO:0005576	extracellular region
0.56	GO:0043025	neuronal cell body
0.49	GO:0030141	secretory granule
0.39	GO:0005794	Golgi apparatus
0.30	GO:0031224	intrinsic component of membrane

sp|P11456|MPRD_BOVIN
Cation-dependent mannose-6-phosphate receptor
Search

M6PR

0.96	Cation-dependent mannose-6-phosphate receptor

0.86	GO:0015761	mannose transport
0.61	GO:0033299	secretion of lysosomal enzymes
0.41	GO:0007041	lysosomal transport
0.41	GO:0061462	protein localization to lysosome
0.40	GO:0006623	protein targeting to vacuole
0.35	GO:0016197	endosomal transport
0.34	GO:0006898	receptor-mediated endocytosis
0.34	GO:0061024	membrane organization
0.33	GO:0007165	signal transduction

0.86	GO:0015578	mannose transmembrane transporter activity
0.85	GO:0005537	mannose binding
0.63	GO:1905394	retromer complex binding
0.38	GO:0019904	protein domain specific binding
0.34	GO:0004888	transmembrane signaling receptor activity

0.77	GO:0000323	lytic vacuole
0.57	GO:0030904	retromer complex
0.55	GO:0005770	late endosome
0.55	GO:0048471	perinuclear region of cytoplasm
0.49	GO:0005802	trans-Golgi network
0.39	GO:0005774	vacuolar membrane
0.35	GO:0030665	clathrin-coated vesicle membrane
0.35	GO:0030133	transport vesicle
0.35	GO:0000139	Golgi membrane
0.34	GO:0005887	integral component of plasma membrane

sp|P11541|PDE6A_BOVIN
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha
Search

PDE6A

0.54	Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha

0.61	GO:0007165	signal transduction
0.60	GO:0007601	visual perception
0.59	GO:0051480	regulation of cytosolic calcium ion concentration
0.55	GO:0046037	GMP metabolic process
0.47	GO:0060041	retina development in camera-type eye
0.45	GO:0009583	detection of light stimulus
0.37	GO:0022400	regulation of rhodopsin mediated signaling pathway
0.37	GO:0045494	photoreceptor cell maintenance
0.36	GO:0071482	cellular response to light stimulus
0.35	GO:0198738	cell-cell signaling by wnt

0.80	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.54	GO:0046872	metal ion binding

0.48	GO:0001750	photoreceptor outer segment
0.39	GO:0060170	ciliary membrane

0.80

GO:0004114

sp|P11834|OPCM_BOVIN
Opioid-binding protein/cell adhesion molecule
Search

OPCML

0.87	Opioid binding protein/cell adhesion molecule like

0.63	GO:0007155	cell adhesion
0.51	GO:0006501	C-terminal protein lipidation
0.50	GO:0008038	neuron recognition
0.44	GO:0032355	response to estradiol
0.44	GO:0021549	cerebellum development
0.44	GO:0010977	negative regulation of neuron projection development

0.42

GO:0005515

protein binding

0.69	GO:0031225	anchored component of membrane
0.50	GO:0005886	plasma membrane
0.50	GO:0070062	extracellular exosome
0.44	GO:0060076	excitatory synapse
0.42	GO:0030424	axon
0.42	GO:0048471	perinuclear region of cytoplasm
0.41	GO:0009986	cell surface
0.30	GO:0016021	integral component of membrane

sp|P11842|CRBA4_BOVIN
Beta-crystallin A4
Search

CRYBA4

0.96	Beta crystallin A4 chain

0.57	GO:0007601	visual perception
0.52	GO:0043010	camera-type eye development
0.37	GO:2000210	positive regulation of anoikis
0.36	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling
0.36	GO:0051898	negative regulation of protein kinase B signaling
0.36	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.36	GO:0032007	negative regulation of TOR signaling
0.35	GO:0001818	negative regulation of cytokine production
0.34	GO:0043043	peptide biosynthetic process
0.34	GO:0044267	cellular protein metabolic process

0.74	GO:0005212	structural constituent of eye lens
0.35	GO:0003735	structural constituent of ribosome
0.34	GO:0005515	protein binding

0.36	GO:0015935	small ribosomal subunit
0.33	GO:0005634	nucleus

sp|P11843|CRBA1_BOVIN
Beta-crystallin A3
Search

CRYBA1

0.97	Beta crystallin A3 chain transcript CN (Fragment)

0.67	GO:0007601	visual perception
0.45	GO:2000210	positive regulation of anoikis
0.44	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling
0.44	GO:0043010	camera-type eye development
0.44	GO:0051898	negative regulation of protein kinase B signaling
0.43	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.43	GO:0032007	negative regulation of TOR signaling
0.43	GO:0001818	negative regulation of cytokine production

0.67	GO:0005212	structural constituent of eye lens
0.39	GO:0042803	protein homodimerization activity

0.38	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm

sp|P11966|ODPB_BOVIN
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial
Search

PDHB

0.55	Mitochondrial pyruvate dehydrogenase e1 component subunit beta

0.57	GO:0006086	acetyl-CoA biosynthetic process from pyruvate
0.51	GO:0006099	tricarboxylic acid cycle
0.46	GO:0043473	pigmentation
0.40	GO:0006006	glucose metabolic process
0.38	GO:0019362	pyridine nucleotide metabolic process
0.37	GO:0006757	ATP generation from ADP
0.37	GO:0016052	carbohydrate catabolic process
0.37	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate
0.33	GO:0006508	proteolysis

0.62	GO:0034604	pyruvate dehydrogenase (NAD+) activity
0.45	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity
0.34	GO:0008234	cysteine-type peptidase activity
0.34	GO:0005515	protein binding

0.56	GO:0045254	pyruvate dehydrogenase complex
0.50	GO:0005654	nucleoplasm
0.47	GO:0005739	mitochondrion
0.37	GO:0070062	extracellular exosome

0.62	EC:1.2.1	GO:0034604
0.62	KEGG:R00209	GO:0034604

sp|P12082|CO5_BOVIN
Complement C5a anaphylatoxin
Search

0.97	Complement C5a anaphylatoxin

0.77	GO:0006956	complement activation
0.74	GO:0006954	inflammatory response
0.74	GO:0010760	negative regulation of macrophage chemotaxis
0.73	GO:0090197	positive regulation of chemokine secretion
0.73	GO:0010951	negative regulation of endopeptidase activity
0.71	GO:0010575	positive regulation of vascular endothelial growth factor production
0.67	GO:0045766	positive regulation of angiogenesis
0.66	GO:0001701	in utero embryonic development
0.49	GO:0002455	humoral immune response mediated by circulating immunoglobulin
0.47	GO:0045087	innate immune response

0.73	GO:0004866	endopeptidase inhibitor activity
0.41	GO:0001664	G-protein coupled receptor binding
0.38	GO:0005125	cytokine activity
0.38	GO:0005126	cytokine receptor binding

0.70	GO:0005615	extracellular space
0.70	GO:0005579	membrane attack complex
0.41	GO:1903561	extracellular vesicle

sp|P12234|MPCP_BOVIN
Phosphate carrier protein, mitochondrial
Search

SLC25A3

0.84	Phosphate carrier proteinserine-threonine

0.45	GO:0006839	mitochondrial transport
0.45	GO:0035435	phosphate ion transmembrane transport
0.34	GO:1902600	hydrogen ion transmembrane transport

0.48	GO:0032403	protein complex binding
0.45	GO:0015114	phosphate ion transmembrane transporter activity
0.38	GO:0015317	phosphate:proton symporter activity

0.52	GO:0043209	myelin sheath
0.45	GO:0005743	mitochondrial inner membrane
0.36	GO:0070062	extracellular exosome
0.33	GO:0005887	integral component of plasma membrane

sp|P12260|F13A_BOVIN
Coagulation factor XIII A chain (Fragment)
Search

F13A1

0.81	Coagulation factor XIII A chain (Fragment)

0.84	GO:0018149	peptide cross-linking
0.83	GO:0072378	blood coagulation, fibrin clot formation
0.36	GO:0002576	platelet degranulation
0.35	GO:0019221	cytokine-mediated signaling pathway
0.33	GO:0042381	hemolymph coagulation
0.33	GO:0006508	proteolysis
0.32	GO:0098869	cellular oxidant detoxification
0.31	GO:0055114	oxidation-reduction process

0.84	GO:0003810	protein-glutamine gamma-glutamyltransferase activity
0.34	GO:0046872	metal ion binding
0.33	GO:0008233	peptidase activity
0.32	GO:0004096	catalase activity
0.32	GO:0020037	heme binding

0.38	GO:0072562	blood microparticle
0.36	GO:0031093	platelet alpha granule lumen

0.84

EC:2.3.2.13

GO:0003810

sp|P12342|IL2RA_BOVIN
Interleukin-2 receptor subunit alpha
Search

IL2RA

0.97	Interleukin-2 receptor subunit alpha

0.87	GO:0038110	interleukin-2-mediated signaling pathway
0.67	GO:0002664	regulation of T cell tolerance induction
0.63	GO:0046013	regulation of T cell homeostatic proliferation
0.63	GO:0006924	activation-induced cell death of T cells
0.61	GO:0042104	positive regulation of activated T cell proliferation
0.60	GO:0042130	negative regulation of T cell proliferation
0.59	GO:0050728	negative regulation of inflammatory response
0.57	GO:0007219	Notch signaling pathway
0.51	GO:0006954	inflammatory response
0.48	GO:0006955	immune response

0.87	GO:0004911	interleukin-2 receptor activity
0.87	GO:0019976	interleukin-2 binding
0.37	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.34	GO:0003735	structural constituent of ribosome
0.34	GO:0008144	drug binding

0.57	GO:0009897	external side of plasma membrane
0.34	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

sp|P12344|AATM_BOVIN
Aspartate aminotransferase, mitochondrial
Search

GOT2

0.49	Aspartate aminotransferase

0.59	GO:0006520	cellular amino acid metabolic process
0.53	GO:0043649	dicarboxylic acid catabolic process
0.52	GO:0045471	response to ethanol
0.50	GO:0015908	fatty acid transport
0.49	GO:0006103	2-oxoglutarate metabolic process
0.48	GO:0009058	biosynthetic process
0.46	GO:0006107	oxaloacetate metabolic process
0.46	GO:1901565	organonitrogen compound catabolic process
0.45	GO:0006106	fumarate metabolic process
0.41	GO:0042537	benzene-containing compound metabolic process

0.81	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity
0.77	GO:0070546	L-phenylalanine aminotransferase activity
0.66	GO:0030170	pyridoxal phosphate binding
0.45	GO:0016212	kynurenine-oxoglutarate transaminase activity
0.37	GO:0042803	protein homodimerization activity
0.37	GO:0016597	amino acid binding
0.37	GO:0005543	phospholipid binding
0.36	GO:0019899	enzyme binding
0.36	GO:0047578	4-hydroxyglutamate transaminase activity
0.34	GO:0003723	RNA binding

0.47	GO:0043209	myelin sheath
0.45	GO:0005739	mitochondrion
0.41	GO:0005886	plasma membrane
0.40	GO:0019866	organelle inner membrane
0.40	GO:0070013	intracellular organelle lumen
0.38	GO:0043204	perikaryon
0.38	GO:0009986	cell surface
0.36	GO:0070062	extracellular exosome
0.34	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

0.81	EC:2.6.1.1	GO:0004069
0.81	KEGG:R00355	GO:0004069

sp|P12378|UGDH_BOVIN
UDP-glucose 6-dehydrogenase
Search

UGDH

0.45	UDP-glucose 6-dehydrogenase

0.57	GO:0001702	gastrulation with mouth forming second
0.53	GO:0055114	oxidation-reduction process
0.47	GO:0003190	atrioventricular valve formation
0.46	GO:0045880	positive regulation of smoothened signaling pathway
0.45	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.45	GO:0007368	determination of left/right symmetry
0.44	GO:0006024	glycosaminoglycan biosynthetic process
0.43	GO:0006065	UDP-glucuronate biosynthetic process
0.34	GO:0006011	UDP-glucose metabolic process
0.34	GO:0000271	polysaccharide biosynthetic process

0.77	GO:0003979	UDP-glucose 6-dehydrogenase activity
0.68	GO:0051287	NAD binding
0.33	GO:0009055	electron transfer activity

0.48	GO:0005654	nucleoplasm
0.44	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.77	EC:1.1.1.22	GO:0003979
0.77	KEGG:R00286	GO:0003979

sp|P12401|PLRP2_BOVIN
Placental prolactin-related protein 2
Search

0.78	Chorionic somatomammotropin hormone 2

0.76	GO:0010469	regulation of receptor activity
0.39	GO:0007595	lactation
0.36	GO:1902895	positive regulation of pri-miRNA transcription by RNA polymerase II
0.36	GO:0001937	negative regulation of endothelial cell proliferation
0.36	GO:0046427	positive regulation of JAK-STAT cascade
0.36	GO:0040014	regulation of multicellular organism growth

0.79	GO:0005179	hormone activity
0.34	GO:0046872	metal ion binding

0.66

GO:0005576

extracellular region

sp|P12402|PLRP3_BOVIN
Placental prolactin-related protein 3
Search

0.97	Chorionic somatomammotropin hormone 2

0.76

GO:0010469

regulation of receptor activity

0.79	GO:0005179	hormone activity
0.33	GO:0046872	metal ion binding

0.66	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

sp|P12624|MARCS_BOVIN
Myristoylated alanine-rich C-kinase substrate
Search

MARCKS

0.97	Myristoylated alanine-rich protein kinase C substrate a

0.60	GO:0051764	actin crosslink formation
0.57	GO:0051017	actin filament bundle assembly
0.55	GO:0051260	protein homooligomerization
0.48	GO:0010842	retina layer formation
0.47	GO:0035914	skeletal muscle cell differentiation
0.46	GO:0007420	brain development
0.46	GO:0060541	respiratory system development
0.43	GO:0016310	phosphorylation
0.42	GO:0003381	epithelial cell morphogenesis involved in gastrulation
0.42	GO:0060027	convergent extension involved in gastrulation

0.79	GO:0005516	calmodulin binding
0.60	GO:0005080	protein kinase C binding
0.55	GO:0051015	actin filament binding
0.52	GO:0042802	identical protein binding
0.45	GO:0016301	kinase activity
0.37	GO:0001786	phosphatidylserine binding
0.32	GO:0003735	structural constituent of ribosome

0.62	GO:0042585	germinal vesicle
0.58	GO:0032432	actin filament bundle
0.55	GO:0005813	centrosome
0.54	GO:0005938	cell cortex
0.41	GO:0070062	extracellular exosome
0.40	GO:0005925	focal adhesion
0.38	GO:0044307	dendritic branch
0.38	GO:0005886	plasma membrane
0.38	GO:0032059	bleb
0.38	GO:0001520	outer dense fiber

sp|P12661|RET3_BOVIN
Retinol-binding protein 3
Search

0.63	Retinol-binding protein 3

0.78	GO:0007601	visual perception
0.61	GO:0006508	proteolysis

0.83	GO:0005501	retinoid binding
0.67	GO:0008236	serine-type peptidase activity
0.30	GO:0043178	alcohol binding
0.30	GO:0019842	vitamin binding

0.30	GO:0033165	interphotoreceptor matrix
0.30	GO:0044420	extracellular matrix component

sp|P12763|FETUA_BOVIN
Alpha-2-HS-glycoprotein
Search

AHSG

0.97

Fetuin-A

0.76	GO:0010951	negative regulation of endopeptidase activity
0.68	GO:0070168	negative regulation of biomineral tissue development
0.65	GO:0006953	acute-phase response
0.65	GO:0050766	positive regulation of phagocytosis
0.64	GO:0030279	negative regulation of ossification
0.64	GO:0030500	regulation of bone mineralization
0.61	GO:0050727	regulation of inflammatory response
0.61	GO:0001503	ossification
0.38	GO:0046627	negative regulation of insulin receptor signaling pathway
0.37	GO:0048731	system development

0.83	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.38	GO:0019210	kinase inhibitor activity
0.35	GO:0005515	protein binding
0.35	GO:0019887	protein kinase regulator activity
0.34	GO:0008191	metalloendopeptidase inhibitor activity

0.71	GO:0005615	extracellular space
0.57	GO:0031012	extracellular matrix
0.54	GO:0005794	Golgi apparatus
0.42	GO:0043230	extracellular organelle
0.40	GO:0031982	vesicle
0.36	GO:0005788	endoplasmic reticulum lumen
0.35	GO:0005886	plasma membrane
0.33	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

sp|P12799|FIBG_BOVIN
Fibrinogen gamma-B chain
Search

FGG

0.97	Fibrinogen gamma polypeptide

0.83	GO:0030168	platelet activation
0.76	GO:0051258	protein polymerization
0.62	GO:0072378	blood coagulation, fibrin clot formation
0.60	GO:0007165	signal transduction
0.59	GO:0034116	positive regulation of heterotypic cell-cell adhesion
0.59	GO:0042730	fibrinolysis
0.58	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.58	GO:0045907	positive regulation of vasoconstriction
0.58	GO:2000352	negative regulation of endothelial cell apoptotic process
0.58	GO:0031639	plasminogen activation

0.79	GO:0030674	protein binding, bridging
0.71	GO:0005102	receptor binding
0.54	GO:0050839	cell adhesion molecule binding
0.45	GO:0005198	structural molecule activity
0.37	GO:0042803	protein homodimerization activity
0.35	GO:0046872	metal ion binding

0.85	GO:0005577	fibrinogen complex
0.58	GO:0031091	platelet alpha granule
0.55	GO:0009897	external side of plasma membrane
0.39	GO:0072562	blood microparticle
0.37	GO:0070062	extracellular exosome
0.36	GO:0005938	cell cortex
0.36	GO:0034774	secretory granule lumen
0.35	GO:0005788	endoplasmic reticulum lumen

sp|P12820|ACE_BOVIN
Angiotensin-converting enzyme (Fragment)
Search

0.41	Angiotensin-converting enzyme (Fragment)

0.71	GO:0071838	cell proliferation in bone marrow
0.71	GO:1903597	negative regulation of gap junction assembly
0.71	GO:2000170	positive regulation of peptidyl-cysteine S-nitrosylation
0.69	GO:1900086	positive regulation of peptidyl-tyrosine autophosphorylation
0.69	GO:1902033	regulation of hematopoietic stem cell proliferation
0.68	GO:0003084	positive regulation of systemic arterial blood pressure
0.66	GO:0002446	neutrophil mediated immunity
0.65	GO:0061098	positive regulation of protein tyrosine kinase activity
0.64	GO:0060047	heart contraction
0.63	GO:0032092	positive regulation of protein binding

0.84	GO:0008241	peptidyl-dipeptidase activity
0.71	GO:0004180	carboxypeptidase activity
0.67	GO:0008237	metallopeptidase activity
0.53	GO:0046872	metal ion binding
0.51	GO:0031711	bradykinin receptor binding
0.49	GO:0031434	mitogen-activated protein kinase kinase binding
0.48	GO:0008240	tripeptidyl-peptidase activity
0.48	GO:0051019	mitogen-activated protein kinase binding
0.48	GO:0031404	chloride ion binding
0.43	GO:0016805	dipeptidase activity

0.48	GO:0005886	plasma membrane
0.48	GO:0005576	extracellular region
0.46	GO:0009986	cell surface
0.45	GO:0005764	lysosome
0.44	GO:0005768	endosome
0.44	GO:0098552	side of membrane
0.40	GO:0097225	sperm midpiece
0.39	GO:0045178	basal part of cell
0.39	GO:0005903	brush border
0.30	GO:0016021	integral component of membrane

0.84

EC:3.4.15

GO:0008241

sp|P13135|CPNS1_BOVIN
Calpain small subunit 1
Search

CAPNS1

0.97	Calpain small subunit 1

0.45	GO:0006508	proteolysis
0.38	GO:0022617	extracellular matrix disassembly
0.36	GO:0070268	cornification
0.36	GO:0016241	regulation of macroautophagy
0.35	GO:0008284	positive regulation of cell proliferation

0.68	GO:0005509	calcium ion binding
0.56	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.36	GO:0005515	protein binding

0.48	GO:0005829	cytosol
0.37	GO:0070062	extracellular exosome
0.37	GO:0005886	plasma membrane

sp|P13182|CX6A1_BOVIN
Cytochrome c oxidase subunit 6A1, mitochondrial
Search

COX6A1

0.80	Cytochrome c oxidase subunit VIa polypeptide 1

0.62	GO:1902600	hydrogen ion transmembrane transport
0.60	GO:0022900	electron transport chain
0.43	GO:0050790	regulation of catalytic activity
0.42	GO:0006119	oxidative phosphorylation
0.42	GO:0009060	aerobic respiration

0.64	GO:0015002	heme-copper terminal oxidase activity
0.64	GO:0016675	oxidoreductase activity, acting on a heme group of donors
0.62	GO:0015078	hydrogen ion transmembrane transporter activity
0.61	GO:0009055	electron transfer activity
0.44	GO:0030234	enzyme regulator activity

0.83	GO:0005751	mitochondrial respiratory chain complex IV
0.36	GO:0043209	myelin sheath
0.30	GO:0031224	intrinsic component of membrane

0.64

GO:0016675

sp|P13183|COX7B_BOVIN
Cytochrome c oxidase subunit 7B, mitochondrial
Search

0.97	Cytochrome c oxidase polypeptide VIIb

0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0022900	electron transport chain
0.48	GO:0007417	central nervous system development
0.35	GO:0060003	copper ion export
0.34	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.34	GO:0006119	oxidative phosphorylation
0.34	GO:0009060	aerobic respiration

0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016675	oxidoreductase activity, acting on a heme group of donors
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity
0.35	GO:0004008	copper-exporting ATPase activity
0.34	GO:0005507	copper ion binding
0.33	GO:1901265	nucleoside phosphate binding
0.32	GO:0036094	small molecule binding

0.79	GO:0005746	mitochondrial respiratory chain
0.47	GO:0045277	respiratory chain complex IV
0.30	GO:0016021	integral component of membrane

0.65

GO:0016675

sp|P13184|CX7A2_BOVIN
Cytochrome c oxidase subunit 7A2, mitochondrial
Search

COX7A2

0.97	Cytochrome c oxidase polypeptide VIIa-liver/heart, mitochondrial

0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0022900	electron transport chain
0.33	GO:0006879	cellular iron ion homeostasis
0.33	GO:0006826	iron ion transport
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity
0.33	GO:0008199	ferric iron binding
0.32	GO:0003676	nucleic acid binding

0.79	GO:0005746	mitochondrial respiratory chain
0.36	GO:0070062	extracellular exosome
0.33	GO:0045277	respiratory chain complex IV
0.30	GO:0031224	intrinsic component of membrane

0.65

GO:0016676

sp|P13204|ANFB_BOVIN
Natriuretic peptides B
Search

NPPB

0.91	B-type natriuretic peptide

0.80	GO:0050880	regulation of blood vessel size
0.76	GO:0010469	regulation of receptor activity
0.63	GO:0007168	receptor guanylyl cyclase signaling pathway
0.59	GO:0006182	cGMP biosynthetic process
0.48	GO:0006457	protein folding
0.39	GO:0035815	positive regulation of renal sodium excretion
0.38	GO:0060038	cardiac muscle cell proliferation
0.38	GO:0035810	positive regulation of urine volume
0.38	GO:0043114	regulation of vascular permeability
0.38	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide

0.79	GO:0005179	hormone activity
0.55	GO:0051427	hormone receptor binding

0.66	GO:0005576	extracellular region
0.44	GO:0043234	protein complex

sp|P13213|SPRC_BOVIN
SPARC
Search

SPARC

0.96	Secreted protein acidic and rich in cysteine

0.61	GO:0007165	signal transduction
0.55	GO:0001501	skeletal system development
0.55	GO:0001937	negative regulation of endothelial cell proliferation
0.54	GO:0010595	positive regulation of endothelial cell migration
0.54	GO:0016525	negative regulation of angiogenesis
0.54	GO:0043473	pigmentation
0.52	GO:0048513	animal organ development
0.52	GO:0071363	cellular response to growth factor stimulus
0.47	GO:0022604	regulation of cell morphogenesis
0.44	GO:0060037	pharyngeal system development

0.84	GO:0050840	extracellular matrix binding
0.83	GO:0005518	collagen binding
0.70	GO:0005509	calcium ion binding

0.76	GO:0005578	proteinaceous extracellular matrix
0.73	GO:0005615	extracellular space
0.58	GO:0031092	platelet alpha granule membrane
0.54	GO:0016363	nuclear matrix
0.50	GO:0009986	cell surface
0.43	GO:0044420	extracellular matrix component
0.36	GO:0071682	endocytic vesicle lumen
0.35	GO:0031093	platelet alpha granule lumen
0.34	GO:0005739	mitochondrion
0.33	GO:0005886	plasma membrane

sp|P13214|ANXA4_BOVIN
Annexin A4
Search

ANXA4

0.61

Annexin

0.58	GO:2000483	negative regulation of interleukin-8 secretion
0.55	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.55	GO:0007219	Notch signaling pathway
0.53	GO:0030855	epithelial cell differentiation
0.49	GO:0006357	regulation of transcription by RNA polymerase II
0.45	GO:0050819	negative regulation of coagulation
0.35	GO:0001822	kidney development
0.35	GO:0043066	negative regulation of apoptotic process
0.34	GO:0006887	exocytosis
0.34	GO:0043086	negative regulation of catalytic activity

0.81	GO:0005544	calcium-dependent phospholipid binding
0.70	GO:0005509	calcium ion binding
0.57	GO:0051059	NF-kappaB binding
0.56	GO:0048306	calcium-dependent protein binding
0.50	GO:0042802	identical protein binding
0.36	GO:0035374	chondroitin sulfate binding
0.36	GO:0004859	phospholipase inhibitor activity
0.35	GO:0008201	heparin binding
0.34	GO:0030246	carbohydrate binding
0.31	GO:0016787	hydrolase activity

0.53	GO:0031965	nuclear membrane
0.53	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0012506	vesicle membrane
0.51	GO:0009986	cell surface
0.42	GO:0005886	plasma membrane
0.37	GO:0045177	apical part of cell
0.37	GO:0070062	extracellular exosome
0.36	GO:0042583	chromaffin granule
0.34	GO:0044433	cytoplasmic vesicle part
0.34	GO:0098805	whole membrane

0.31

GO:0016787

sp|P13271|QCR8_BOVIN
Cytochrome b-c1 complex subunit 8
Search

UQCRQ

0.93	Mitochondrial ubiquinol-cytochrome c reductase ubiquinone-binding protein qp-c

0.61	GO:0022900	electron transport chain
0.60	GO:0021539	subthalamus development
0.59	GO:0021860	pyramidal neuron development
0.58	GO:0021794	thalamus development
0.58	GO:0021548	pons development
0.58	GO:0021854	hypothalamus development
0.57	GO:0021680	cerebellar Purkinje cell layer development
0.56	GO:0030901	midbrain development
0.56	GO:0021766	hippocampus development
0.42	GO:0006119	oxidative phosphorylation

0.74	GO:0016681	oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor
0.62	GO:0009055	electron transfer activity
0.36	GO:0005230	extracellular ligand-gated ion channel activity
0.35	GO:0004888	transmembrane signaling receptor activity
0.35	GO:0030554	adenyl nucleotide binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0048039	ubiquinone binding
0.33	GO:0005515	protein binding

0.49	GO:0005750	mitochondrial respiratory chain complex III
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.74

GO:0016681

sp|P13272|UCRI_BOVIN
Cytochrome b-c1 complex subunit Rieske, mitochondrial
Search

UQCRFS1

0.69	Ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1

0.61	GO:0022900	electron transport chain
0.37	GO:0009725	response to hormone
0.37	GO:0046677	response to antibiotic
0.36	GO:0042493	response to drug
0.33	GO:0006119	oxidative phosphorylation
0.33	GO:0045333	cellular respiration

0.74	GO:0016681	oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor
0.71	GO:0051537	2 iron, 2 sulfur cluster binding
0.62	GO:0009055	electron transfer activity
0.38	GO:0046872	metal ion binding
0.37	GO:0032403	protein complex binding

0.61	GO:0070469	respiratory chain
0.61	GO:0031966	mitochondrial membrane
0.61	GO:0019866	organelle inner membrane
0.47	GO:0098798	mitochondrial protein complex
0.46	GO:0070069	cytochrome complex
0.45	GO:1990204	oxidoreductase complex
0.42	GO:0098796	membrane protein complex
0.40	GO:0043209	myelin sheath
0.30	GO:0016021	integral component of membrane

0.74

GO:0016681

sp|P13384|IBP2_BOVIN
Insulin-like growth factor-binding protein 2
Search

IGFBP2

0.96	Insulin like growth factor binding protein 2

0.71	GO:0001558	regulation of cell growth
0.60	GO:0042104	positive regulation of activated T cell proliferation
0.54	GO:0032868	response to insulin
0.53	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway
0.41	GO:0010226	response to lithium ion
0.41	GO:0032501	multicellular organismal process
0.41	GO:0032502	developmental process
0.40	GO:0032355	response to estradiol
0.40	GO:0043627	response to estrogen
0.40	GO:0032526	response to retinoic acid

0.83	GO:0005520	insulin-like growth factor binding
0.35	GO:0005102	receptor binding
0.33	GO:0016746	transferase activity, transferring acyl groups

0.66	GO:0005576	extracellular region
0.39	GO:0016324	apical plasma membrane
0.38	GO:0031410	cytoplasmic vesicle
0.30	GO:0016021	integral component of membrane

0.33

EC:2.3

GO:0016746

sp|P13536|ACHG_BOVIN
Acetylcholine receptor subunit gamma
Search

CHRNG

0.95	Cholinergic receptor nicotinic gamma subunit

0.79	GO:0060079	excitatory postsynaptic potential
0.65	GO:0007271	synaptic transmission, cholinergic
0.60	GO:0034220	ion transmembrane transport
0.58	GO:0035094	response to nicotine
0.57	GO:0007274	neuromuscular synaptic transmission
0.45	GO:0006812	cation transport

0.83	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0099600	transmembrane receptor activity
0.59	GO:0042166	acetylcholine binding

0.79	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.64	GO:0005892	acetylcholine-gated channel complex

sp|P13600|NGF_BOVIN
Beta-nerve growth factor
Search

NGF

0.76	Beta-nerve growth factor

0.75	GO:0010469	regulation of receptor activity
0.52	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors
0.50	GO:0010951	negative regulation of endopeptidase activity
0.50	GO:0048812	neuron projection morphogenesis
0.46	GO:0010628	positive regulation of gene expression
0.45	GO:0043524	negative regulation of neuron apoptotic process
0.43	GO:0045664	regulation of neuron differentiation
0.43	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.42	GO:0007267	cell-cell signaling
0.37	GO:0038179	neurotrophin signaling pathway

0.78	GO:0008083	growth factor activity
0.56	GO:0005163	nerve growth factor receptor binding
0.54	GO:0008191	metalloendopeptidase inhibitor activity
0.36	GO:0038177	death receptor agonist activity
0.36	GO:0008047	enzyme activator activity
0.35	GO:0030546	receptor activator activity
0.35	GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process
0.34	GO:0019887	protein kinase regulator activity
0.34	GO:0005057	signal transducer activity, downstream of receptor
0.33	GO:0042802	identical protein binding

0.42	GO:0005576	extracellular region
0.41	GO:0031410	cytoplasmic vesicle
0.37	GO:0005796	Golgi lumen
0.35	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0016020	membrane

sp|P13605|FMOD_BOVIN
Fibromodulin
Search

FMOD

0.97	Fibromodulin

0.64	GO:0030199	collagen fibril organization
0.49	GO:0032501	multicellular organismal process
0.48	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.48	GO:0000904	cell morphogenesis involved in differentiation
0.47	GO:0120036	plasma membrane bounded cell projection organization
0.41	GO:0032914	positive regulation of transforming growth factor beta1 production
0.38	GO:0045944	positive regulation of transcription by RNA polymerase II
0.36	GO:0042340	keratan sulfate catabolic process
0.36	GO:0070848	response to growth factor
0.36	GO:0018146	keratan sulfate biosynthetic process

0.41	GO:0005518	collagen binding
0.32	GO:0004930	G-protein coupled receptor activity

0.74	GO:0005578	proteinaceous extracellular matrix
0.56	GO:0005615	extracellular space
0.39	GO:0044420	extracellular matrix component
0.38	GO:0005581	collagen trimer
0.37	GO:0099512	supramolecular fiber
0.36	GO:0043202	lysosomal lumen
0.36	GO:0005796	Golgi lumen
0.33	GO:1903561	extracellular vesicle
0.30	GO:0031224	intrinsic component of membrane

sp|P13608|PGCA_BOVIN
Aggrecan core protein
Search

ACAN

0.91

Aggrecan

0.72	GO:0007155	cell adhesion
0.62	GO:0001502	cartilage condensation
0.62	GO:0002063	chondrocyte development
0.61	GO:0030199	collagen fibril organization
0.60	GO:0030166	proteoglycan biosynthetic process
0.57	GO:0007507	heart development
0.49	GO:0007417	central nervous system development
0.39	GO:0042340	keratan sulfate catabolic process
0.39	GO:0018146	keratan sulfate biosynthetic process
0.38	GO:0022617	extracellular matrix disassembly

0.84	GO:0005540	hyaluronic acid binding
0.59	GO:0005509	calcium ion binding
0.50	GO:0005201	extracellular matrix structural constituent
0.42	GO:0030246	carbohydrate binding
0.39	GO:0005515	protein binding

0.58	GO:0005604	basement membrane
0.53	GO:0005615	extracellular space
0.38	GO:0043202	lysosomal lumen
0.38	GO:0005796	Golgi lumen
0.34	GO:0072534	perineuronal net
0.34	GO:0043025	neuronal cell body
0.33	GO:0043005	neuron projection
0.30	GO:0016020	membrane

sp|P13619|AT5F1_BOVIN
ATP synthase F(0) complex subunit B1, mitochondrial
Search

ATP5F1

0.42	ATP synthase peripheral stalk-membrane subunit b

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.43	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.38	GO:0021762	substantia nigra development
0.35	GO:0042407	cristae formation
0.34	GO:0050909	sensory perception of taste
0.34	GO:0006839	mitochondrial transport
0.34	GO:0046907	intracellular transport
0.33	GO:0007165	signal transduction

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.44	GO:0016887	ATPase activity
0.43	GO:0022853	active ion transmembrane transporter activity
0.42	GO:0015399	primary active transmembrane transporter activity
0.33	GO:0005515	protein binding
0.33	GO:0004871	signal transducer activity

0.78	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
0.50	GO:0043209	myelin sheath
0.46	GO:0005654	nucleoplasm
0.36	GO:0070062	extracellular exosome
0.34	GO:0005759	mitochondrial matrix
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.44

GO:0016887

sp|P13620|ATP5H_BOVIN
ATP synthase subunit d, mitochondrial
Search

ATP5H

0.73	ATP synthase subunit d, mitochondrial

0.69	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.68	GO:0006754	ATP biosynthetic process
0.48	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.35	GO:0042407	cristae formation
0.34	GO:0006839	mitochondrial transport
0.33	GO:0046907	intracellular transport

0.62	GO:0015078	hydrogen ion transmembrane transporter activity
0.49	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
0.48	GO:0019829	cation-transporting ATPase activity

0.76	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
0.57	GO:0045265	proton-transporting ATP synthase, stator stalk
0.46	GO:0043209	myelin sheath
0.43	GO:0005654	nucleoplasm
0.36	GO:0070062	extracellular exosome

sp|P13621|ATPO_BOVIN
ATP synthase subunit O, mitochondrial
Search

ATP5O

0.91	Mitochondrial ATP synthase subunit OSCP subunit

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.69	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.41	GO:0006839	mitochondrial transport
0.39	GO:0046907	intracellular transport
0.35	GO:0042407	cristae formation
0.33	GO:0006334	nucleosome assembly

0.72	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism
0.36	GO:0005496	steroid binding
0.35	GO:0008144	drug binding
0.35	GO:0032403	protein complex binding

0.46	GO:0043209	myelin sheath
0.45	GO:0005753	mitochondrial proton-transporting ATP synthase complex
0.37	GO:0031012	extracellular matrix
0.36	GO:0070062	extracellular exosome
0.36	GO:0005886	plasma membrane
0.36	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)
0.34	GO:0005634	nucleus
0.34	GO:0045269	proton-transporting ATP synthase, central stalk
0.30	GO:0016021	integral component of membrane

sp|P13696|PEBP1_BOVIN
Phosphatidylethanolamine-binding protein 1
Search

PEBP1

0.63	Phosphatidylethanolamine-binding protein 1

0.55	GO:0010951	negative regulation of endopeptidase activity
0.51	GO:0060409	positive regulation of acetylcholine metabolic process
0.51	GO:0048240	sperm capacitation
0.49	GO:0051412	response to corticosterone
0.49	GO:0010243	response to organonitrogen compound
0.48	GO:0043950	positive regulation of cAMP-mediated signaling
0.48	GO:0051602	response to electrical stimulus
0.48	GO:0042755	eating behavior
0.48	GO:0002026	regulation of the force of heart contraction
0.48	GO:0014823	response to activity

0.70	GO:0019901	protein kinase binding
0.56	GO:0004867	serine-type endopeptidase inhibitor activity
0.53	GO:0008289	lipid binding
0.44	GO:0032559	adenyl ribonucleotide binding
0.43	GO:0008144	drug binding
0.43	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0005102	receptor binding
0.40	GO:0019210	kinase inhibitor activity
0.38	GO:0003723	RNA binding

0.49	GO:0043209	myelin sheath
0.47	GO:0043679	axon terminus
0.46	GO:0009986	cell surface
0.46	GO:0005791	rough endoplasmic reticulum
0.46	GO:0008021	synaptic vesicle
0.46	GO:0043025	neuronal cell body
0.45	GO:0045177	apical part of cell
0.45	GO:0005615	extracellular space
0.45	GO:0005741	mitochondrial outer membrane
0.43	GO:1903561	extracellular vesicle

sp|P13752|HA1A_BOVIN
BOLA class I histocompatibility antigen, alpha chain BL3-6
Search

BOLA

0.42	BOLA class I histocompatibility antigen, alpha chain BL3-6

0.82	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I
0.74	GO:0006955	immune response

0.81	GO:0042612	MHC class I protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|P13753|HA1B_BOVIN
BOLA class I histocompatibility antigen, alpha chain BL3-7
Search

BOLA

0.42	BOLA class I histocompatibility antigen, alpha chain BL3-7

0.82	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I
0.74	GO:0006955	immune response

0.81	GO:0042612	MHC class I protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|P13789|TNNT2_BOVIN
Troponin T, cardiac muscle
Search

TNNT2

0.92	Low Mr mutant cardiac troponin T

0.83	GO:0006937	regulation of muscle contraction
0.61	GO:0030049	muscle filament sliding
0.60	GO:0055010	ventricular cardiac muscle tissue morphogenesis
0.58	GO:0008016	regulation of heart contraction
0.57	GO:0060047	heart contraction
0.57	GO:0051592	response to calcium ion
0.57	GO:0006941	striated muscle contraction
0.55	GO:0032780	negative regulation of ATPase activity
0.55	GO:0032781	positive regulation of ATPase activity
0.44	GO:0097534	lymphoid lineage cell migration

0.61	GO:0030172	troponin C binding
0.60	GO:0031013	troponin I binding
0.57	GO:0005523	tropomyosin binding
0.51	GO:0003779	actin binding
0.37	GO:0030674	protein binding, bridging
0.35	GO:0005200	structural constituent of cytoskeleton
0.34	GO:0016887	ATPase activity
0.32	GO:0046872	metal ion binding

0.84	GO:0005861	troponin complex
0.57	GO:0097512	cardiac myofibril
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.34

GO:0016887

sp|P13909|PAI1_BOVIN
Plasminogen activator inhibitor 1
Search

SERPINE1

0.93	Clade E serpine peptidase inhibitor

0.66	GO:0035491	positive regulation of leukotriene production involved in inflammatory response
0.66	GO:1901331	positive regulation of odontoblast differentiation
0.66	GO:0061044	negative regulation of vascular wound healing
0.66	GO:0097187	dentinogenesis
0.65	GO:0010757	negative regulation of plasminogen activation
0.65	GO:2000098	negative regulation of smooth muscle cell-matrix adhesion
0.64	GO:0033629	negative regulation of cell adhesion mediated by integrin
0.64	GO:0051918	negative regulation of fibrinolysis
0.63	GO:0090399	replicative senescence
0.63	GO:0014912	negative regulation of smooth muscle cell migration

0.60	GO:0004867	serine-type endopeptidase inhibitor activity
0.60	GO:0002020	protease binding
0.54	GO:0005102	receptor binding
0.37	GO:0035375	zymogen binding
0.37	GO:0008233	peptidase activity
0.36	GO:0008201	heparin binding
0.33	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process

0.73	GO:0005615	extracellular space
0.58	GO:1903561	extracellular vesicle
0.55	GO:0031012	extracellular matrix
0.39	GO:0030141	secretory granule
0.37	GO:0031232	extrinsic component of external side of plasma membrane
0.36	GO:0060205	cytoplasmic vesicle lumen
0.35	GO:0031594	neuromuscular junction
0.35	GO:0005829	cytosol
0.35	GO:0048475	coated membrane
0.34	GO:0098796	membrane protein complex

0.37

GO:0008233

sp|P14099|PDE2A_BOVIN
cGMP-dependent 3',5'-cyclic phosphodiesterase
Search

PDE2A

0.57	Phosphodiesterase

0.61	GO:0033159	negative regulation of protein import into nucleus, translocation
0.60	GO:0007165	signal transduction
0.60	GO:0071321	cellular response to cGMP
0.60	GO:0046069	cGMP catabolic process
0.60	GO:0043117	positive regulation of vascular permeability
0.60	GO:0036006	cellular response to macrophage colony-stimulating factor stimulus
0.59	GO:0043116	negative regulation of vascular permeability
0.57	GO:0006198	cAMP catabolic process
0.56	GO:1904613	cellular response to 2,3,7,8-tetrachlorodibenzodioxine
0.54	GO:0035690	cellular response to drug

0.79	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.58	GO:0030553	cGMP binding
0.56	GO:0030911	TPR domain binding
0.54	GO:0046872	metal ion binding
0.53	GO:0030552	cAMP binding
0.49	GO:0042803	protein homodimerization activity
0.42	GO:0008144	drug binding
0.38	GO:0036004	GAF domain binding
0.37	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.36	GO:0005096	GTPase activator activity

0.54	GO:0048471	perinuclear region of cytoplasm
0.50	GO:0005741	mitochondrial outer membrane
0.47	GO:0005829	cytosol
0.46	GO:0042734	presynaptic membrane
0.45	GO:0005634	nucleus
0.44	GO:0005743	mitochondrial inner membrane
0.43	GO:0005759	mitochondrial matrix
0.42	GO:0005794	Golgi apparatus
0.41	GO:0005783	endoplasmic reticulum
0.37	GO:0030425	dendrite

0.79

GO:0004114

sp|P14100|PDE1A_BOVIN
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A
Search

PDE1A

0.56	Phosphodiesterase

0.60	GO:0007165	signal transduction
0.41	GO:0046069	cGMP catabolic process
0.41	GO:0034391	regulation of smooth muscle cell apoptotic process
0.40	GO:0006198	cAMP catabolic process
0.40	GO:0048660	regulation of smooth muscle cell proliferation
0.39	GO:0048793	pronephros development
0.36	GO:0007608	sensory perception of smell

0.79	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.54	GO:0046872	metal ion binding
0.40	GO:0030553	cGMP binding
0.37	GO:0005516	calmodulin binding

0.39	GO:0043025	neuronal cell body
0.36	GO:0005929	cilium
0.36	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.79

GO:0004114

sp|P14568|ASSY_BOVIN
Argininosuccinate synthase
Search

ASS1

0.46	Argininosuccinate synthetase

0.72	GO:0006526	arginine biosynthetic process
0.62	GO:0000053	argininosuccinate metabolic process
0.60	GO:0000050	urea cycle
0.56	GO:0071499	cellular response to laminar fluid shear stress
0.55	GO:0000052	citrulline metabolic process
0.54	GO:0045429	positive regulation of nitric oxide biosynthetic process
0.53	GO:1903038	negative regulation of leukocyte cell-cell adhesion
0.53	GO:0007623	circadian rhythm
0.52	GO:0006531	aspartate metabolic process
0.36	GO:0071418	cellular response to amine stimulus

0.80	GO:0004055	argininosuccinate synthase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0016597	amino acid binding
0.49	GO:0042802	identical protein binding
0.35	GO:0015643	toxic substance binding
0.34	GO:0003723	RNA binding
0.33	GO:0004386	helicase activity
0.32	GO:0046872	metal ion binding

0.52	GO:0043209	myelin sheath
0.47	GO:0005829	cytosol
0.43	GO:0005739	mitochondrion
0.37	GO:0070062	extracellular exosome
0.36	GO:0070852	cell body fiber
0.35	GO:0043204	perikaryon
0.35	GO:0005764	lysosome
0.34	GO:0031968	organelle outer membrane
0.34	GO:0005783	endoplasmic reticulum
0.33	GO:0005634	nucleus

0.80

EC:6.3.4.5

GO:0004055

sp|P14622|COX8A_BOVIN
Cytochrome c oxidase subunit 8A, mitochondrial
Search

COX8A

0.97	Cytochrome c oxidase polypeptide VIII-liver/heart

0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0022900	electron transport chain
0.43	GO:0006119	oxidative phosphorylation
0.43	GO:0009060	aerobic respiration

0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity
0.35	GO:0005515	protein binding

0.54	GO:0005739	mitochondrion
0.54	GO:0019866	organelle inner membrane
0.48	GO:0045277	respiratory chain complex IV
0.30	GO:0031224	intrinsic component of membrane

0.65

GO:0016676

sp|P14769|GGTA1_BOVIN
N-acetyllactosaminide alpha-1,3-galactosyltransferase
Search

0.94	Glycosyltransferase 6 domain-containing protein 1

0.60	GO:0005975	carbohydrate metabolic process
0.52	GO:0033580	protein galactosylation at cell surface
0.48	GO:0030259	lipid glycosylation
0.48	GO:0009247	glycolipid biosynthetic process
0.43	GO:0006687	glycosphingolipid metabolic process
0.43	GO:0030148	sphingolipid biosynthetic process
0.33	GO:1901748	leukotriene D4 metabolic process
0.33	GO:0019370	leukotriene biosynthetic process
0.32	GO:0044272	sulfur compound biosynthetic process
0.32	GO:0043043	peptide biosynthetic process

0.69	GO:0016758	transferase activity, transferring hexosyl groups
0.45	GO:0008194	UDP-glycosyltransferase activity
0.38	GO:0046872	metal ion binding
0.33	GO:0140103	catalytic activity, acting on a glycoprotein

0.48	GO:0005794	Golgi apparatus
0.46	GO:0031982	vesicle
0.43	GO:0098588	bounding membrane of organelle
0.42	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.69

EC:2.4.1

GO:0016758

sp|P14790|68MP_BOVIN
6.8 kDa mitochondrial proteolipid
Search

0.97	Mitochondrial proteolipid

0.36	GO:0006915	apoptotic process
0.36	GO:0045786	negative regulation of cell cycle

0.35

GO:0008134

transcription factor binding

0.61	GO:0005739	mitochondrion
0.40	GO:0045259	proton-transporting ATP synthase complex
0.38	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P14893|3BHS_BOVIN
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase
Search

0.50	3 beta-hydroxysteroid dehydrogenase isomerase VI

0.78	GO:0006694	steroid biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.40	GO:0034754	cellular hormone metabolic process
0.39	GO:0042446	hormone biosynthetic process
0.38	GO:0014070	response to organic cyclic compound
0.37	GO:0010288	response to lead ion
0.37	GO:0008211	glucocorticoid metabolic process
0.37	GO:0033327	Leydig cell differentiation
0.37	GO:0034698	response to gonadotropin
0.37	GO:0021766	hippocampus development

0.83	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity
0.54	GO:0102294	cholesterol dehydrogenase activity
0.53	GO:0004769	steroid delta-isomerase activity
0.38	GO:0010181	FMN binding
0.36	GO:0005496	steroid binding
0.36	GO:0035410	dihydrotestosterone 17-beta-dehydrogenase activity
0.35	GO:0030283	testosterone dehydrogenase [NAD(P)] activity
0.35	GO:0051287	NAD binding
0.34	GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity
0.33	GO:0016651	oxidoreductase activity, acting on NAD(P)H

0.45	GO:0005789	endoplasmic reticulum membrane
0.44	GO:0005758	mitochondrial intermembrane space
0.43	GO:0031966	mitochondrial membrane
0.40	GO:0019866	organelle inner membrane
0.40	GO:0097425	smooth endoplasmic reticulum part
0.36	GO:0098588	bounding membrane of organelle
0.30	GO:0031224	intrinsic component of membrane

0.83

EC:1.1.1.145

GO:0003854

sp|P15101|DOPO_BOVIN
Dopamine beta-hydroxylase
Search

DBH

0.96	Dopamine beta-hydroxylase

0.60	GO:0042420	dopamine catabolic process
0.60	GO:0042421	norepinephrine biosynthetic process
0.59	GO:0042309	homoiothermy
0.57	GO:0042711	maternal behavior
0.56	GO:0001975	response to amphetamine
0.56	GO:0045907	positive regulation of vasoconstriction
0.56	GO:0048265	response to pain
0.56	GO:0001974	blood vessel remodeling
0.56	GO:0042596	fear response
0.56	GO:0048149	behavioral response to ethanol

0.84	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
0.72	GO:0005507	copper ion binding
0.40	GO:0031418	L-ascorbic acid binding
0.32	GO:0004672	protein kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0003677	DNA binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0008144	drug binding

0.57	GO:0034774	secretory granule lumen
0.57	GO:0030667	secretory granule membrane
0.51	GO:0005615	extracellular space
0.50	GO:0005815	microtubule organizing center
0.48	GO:0005783	endoplasmic reticulum
0.43	GO:0042583	chromaffin granule
0.40	GO:0030658	transport vesicle membrane
0.36	GO:0043005	neuron projection
0.35	GO:0043025	neuronal cell body
0.34	GO:0045177	apical part of cell

0.84

EC:1.14.17

GO:0016715

sp|P15103|GLNA_BOVIN
Glutamine synthetase
Search

GLUL

0.46	Glutamine synthetase

0.76	GO:0006542	glutamine biosynthetic process
0.49	GO:0008283	cell proliferation
0.48	GO:0009749	response to glucose
0.47	GO:0031667	response to nutrient levels
0.44	GO:0031668	cellular response to extracellular stimulus
0.41	GO:0033554	cellular response to stress
0.39	GO:0051968	positive regulation of synaptic transmission, glutamatergic
0.39	GO:0019676	ammonia assimilation cycle
0.39	GO:0032024	positive regulation of insulin secretion
0.38	GO:0050679	positive regulation of epithelial cell proliferation

0.76	GO:0004356	glutamate-ammonia ligase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0042802	identical protein binding
0.43	GO:0004351	glutamate decarboxylase activity
0.40	GO:0016595	glutamate binding
0.39	GO:0045503	dynein light chain binding
0.37	GO:0030145	manganese ion binding
0.35	GO:0000287	magnesium ion binding

0.50	GO:0097386	glial cell projection
0.48	GO:0043209	myelin sheath
0.47	GO:0044297	cell body
0.45	GO:0005829	cytosol
0.43	GO:0005739	mitochondrion
0.39	GO:0043679	axon terminus
0.38	GO:0005791	rough endoplasmic reticulum
0.38	GO:0036477	somatodendritic compartment
0.36	GO:0070062	extracellular exosome
0.35	GO:0043234	protein complex

0.76	EC:6.3.1.2	GO:0004356
0.76	KEGG:R00253	GO:0004356

sp|P15150|C11B1_BOVIN
Cytochrome P450 11B1, mitochondrial
Search

0.76	Cholesterol side-chain cleavage enzyme, mitochondrial

0.68	GO:0006700	C21-steroid hormone biosynthetic process
0.61	GO:0034650	cortisol metabolic process
0.61	GO:0032341	aldosterone metabolic process
0.61	GO:0006705	mineralocorticoid biosynthetic process
0.53	GO:0006704	glucocorticoid biosynthetic process
0.53	GO:0055114	oxidation-reduction process
0.52	GO:0008203	cholesterol metabolic process
0.52	GO:0046184	aldehyde biosynthetic process
0.50	GO:1901617	organic hydroxy compound biosynthetic process
0.50	GO:0042181	ketone biosynthetic process

0.69	GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen
0.68	GO:0008395	steroid hydroxylase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.35	GO:0005496	steroid binding
0.33	GO:0004743	pyruvate kinase activity
0.33	GO:0030955	potassium ion binding
0.32	GO:0000287	magnesium ion binding
0.32	GO:0016301	kinase activity

0.54	GO:0005739	mitochondrion
0.47	GO:0031967	organelle envelope
0.47	GO:0031090	organelle membrane
0.35	GO:0030425	dendrite
0.34	GO:0030176	integral component of endoplasmic reticulum membrane

0.69

EC:1.14.15

GO:0016713

sp|P15246|PIMT_BOVIN
Protein-L-isoaspartate(D-aspartate) O-methyltransferase
Search

PCMT1

0.44	L-isoaspartyl protein carboxyl methyltransferase

0.73	GO:0008213	protein alkylation
0.67	GO:0043414	macromolecule methylation
0.35	GO:0010667	negative regulation of cardiac muscle cell apoptotic process
0.35	GO:0045471	response to ethanol
0.35	GO:0071456	cellular response to hypoxia
0.34	GO:0007568	aging
0.34	GO:0030091	protein repair
0.34	GO:0046498	S-adenosylhomocysteine metabolic process
0.34	GO:0046500	S-adenosylmethionine metabolic process
0.32	GO:0042254	ribosome biogenesis

0.79	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity
0.36	GO:0045296	cadherin binding

0.47	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.35	GO:0031526	brush border membrane
0.35	GO:0043204	perikaryon
0.34	GO:0016323	basolateral plasma membrane
0.34	GO:0043005	neuron projection
0.30	GO:0016021	integral component of membrane

0.79

EC:2.1.1.77

GO:0004719

sp|P15396|ENPP3_BOVIN
Ectonucleotide pyrophosphatase/phosphodiesterase family member 3
Search

ENPP3

0.47	Ectonucleotide pyrophosphatase/phosphodiesterase 3

0.72	GO:0006955	immune response
0.70	GO:0006898	receptor-mediated endocytosis
0.54	GO:0009143	nucleoside triphosphate catabolic process
0.48	GO:0030505	inorganic diphosphate transport
0.45	GO:0030730	sequestering of triglyceride
0.45	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process
0.45	GO:0045719	negative regulation of glycogen biosynthetic process
0.45	GO:0031953	negative regulation of protein autophosphorylation
0.44	GO:0046325	negative regulation of glucose import
0.44	GO:0046627	negative regulation of insulin receptor signaling pathway

0.79	GO:0005044	scavenger receptor activity
0.77	GO:0001871	pattern binding
0.68	GO:0030246	carbohydrate binding
0.53	GO:0046872	metal ion binding
0.52	GO:0047429	nucleoside-triphosphate diphosphatase activity
0.51	GO:0004528	phosphodiesterase I activity
0.50	GO:0003676	nucleic acid binding
0.47	GO:0004551	nucleotide diphosphatase activity
0.44	GO:0005158	insulin receptor binding
0.41	GO:0042803	protein homodimerization activity

0.51	GO:0048471	perinuclear region of cytoplasm
0.42	GO:0005576	extracellular region
0.42	GO:0009986	cell surface
0.37	GO:0005886	plasma membrane
0.35	GO:0031982	vesicle
0.35	GO:0005765	lysosomal membrane
0.30	GO:0016021	integral component of membrane

0.52

EC:3.6.1.19

GO:0047429

sp|P15467|RNAS4_BOVIN
Ribonuclease 4
Search

RNASE4

0.47	Ribonuclease pancreatic

0.63	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.42	GO:0016070	RNA metabolic process
0.36	GO:0009267	cellular response to starvation
0.34	GO:0098542	defense response to other organism
0.34	GO:0009615	response to virus
0.34	GO:0002252	immune effector process
0.33	GO:0050691	regulation of defense response to virus by host
0.33	GO:0001525	angiogenesis
0.33	GO:0009617	response to bacterium
0.32	GO:0009966	regulation of signal transduction

0.65	GO:0004519	endonuclease activity
0.51	GO:0003676	nucleic acid binding
0.48	GO:0004540	ribonuclease activity
0.34	GO:0005515	protein binding

0.51	GO:0005576	extracellular region
0.36	GO:0031982	vesicle
0.33	GO:0046658	anchored component of plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P15497|APOA1_BOVIN
Apolipoprotein A-I
Search

APOA1

0.97	apolipoprotein A-I precursor

0.75	GO:0042157	lipoprotein metabolic process
0.74	GO:0006869	lipid transport
0.73	GO:0008203	cholesterol metabolic process
0.72	GO:0030300	regulation of intestinal cholesterol absorption
0.71	GO:0034380	high-density lipoprotein particle assembly
0.71	GO:0010873	positive regulation of cholesterol esterification
0.71	GO:0060354	negative regulation of cell adhesion molecule production
0.71	GO:0018158	protein oxidation
0.70	GO:0010903	negative regulation of very-low-density lipoprotein particle remodeling
0.70	GO:0034369	plasma lipoprotein particle remodeling

0.73	GO:0070653	high-density lipoprotein particle receptor binding
0.72	GO:0008289	lipid binding
0.72	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity
0.70	GO:0008035	high-density lipoprotein particle binding
0.70	GO:0034191	apolipoprotein A-I receptor binding
0.69	GO:0017127	cholesterol transporter activity
0.69	GO:0045499	chemorepellent activity
0.67	GO:0001540	amyloid-beta binding
0.66	GO:0043178	alcohol binding
0.60	GO:0031072	heat shock protein binding

0.76	GO:0034364	high-density lipoprotein particle
0.67	GO:0034385	triglyceride-rich plasma lipoprotein particle
0.62	GO:0030139	endocytic vesicle
0.58	GO:0031012	extracellular matrix
0.52	GO:0042627	chylomicron
0.51	GO:0072562	blood microparticle
0.41	GO:0034362	low-density lipoprotein particle
0.39	GO:0009986	cell surface
0.38	GO:0070062	extracellular exosome
0.37	GO:0034774	secretory granule lumen

sp|P15506|NPMA_BOVIN
Morphine-modulating neuropeptide A
Search

0.25	Morphine-modulating neuropeptide A

0.72	GO:0010469	regulation of receptor activity
0.62	GO:0060079	excitatory postsynaptic potential
0.58	GO:0007218	neuropeptide signaling pathway

0.81	GO:0005184	neuropeptide hormone activity
0.63	GO:0001664	G-protein coupled receptor binding

0.67	GO:0043204	perikaryon
0.66	GO:0043679	axon terminus
0.63	GO:0030425	dendrite
0.61	GO:0098794	postsynapse
0.58	GO:0005615	extracellular space

sp|P15507|NPMB_BOVIN
Morphine-modulating neuropeptide B
Search

sp|P15690|NDUS1_BOVIN
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
Search

NDUFS1

0.90	NADH:ubiquinone oxidoreductase core subunit S1

0.75	GO:0008637	apoptotic mitochondrial changes
0.71	GO:0051881	regulation of mitochondrial membrane potential
0.69	GO:0042773	ATP synthesis coupled electron transport
0.62	GO:0072593	reactive oxygen species metabolic process

0.69	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.64	GO:0051536	iron-sulfur cluster binding
0.60	GO:0009055	electron transfer activity
0.34	GO:0046872	metal ion binding

0.71	GO:0005747	mitochondrial respiratory chain complex I
0.69	GO:0043209	myelin sheath
0.67	GO:0005758	mitochondrial intermembrane space
0.59	GO:0045272	plasma membrane respiratory chain complex I

0.69

GO:0008137

sp|P15691|VEGFA_BOVIN
Vascular endothelial growth factor A
Search

VEGFA

0.87	vascular endothelial growth factor A precursor

0.75	GO:0010469	regulation of receptor activity
0.52	GO:0001938	positive regulation of endothelial cell proliferation
0.52	GO:0050927	positive regulation of positive chemotaxis
0.51	GO:0045766	positive regulation of angiogenesis
0.51	GO:1903570	regulation of protein kinase D signaling
0.51	GO:0048010	vascular endothelial growth factor receptor signaling pathway
0.50	GO:0010595	positive regulation of endothelial cell migration
0.50	GO:0001525	angiogenesis
0.50	GO:1900086	positive regulation of peptidyl-tyrosine autophosphorylation
0.50	GO:0038091	positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway

0.78	GO:0008083	growth factor activity
0.76	GO:0008201	heparin binding
0.54	GO:0043183	vascular endothelial growth factor receptor 1 binding
0.53	GO:0043184	vascular endothelial growth factor receptor 2 binding
0.49	GO:0001968	fibronectin binding
0.49	GO:0005161	platelet-derived growth factor receptor binding
0.49	GO:0042056	chemoattractant activity
0.47	GO:0005125	cytokine activity
0.38	GO:0038191	neuropilin binding
0.37	GO:0050840	extracellular matrix binding

0.46	GO:0030141	secretory granule
0.46	GO:0005615	extracellular space
0.45	GO:0009986	cell surface
0.35	GO:0005578	proteinaceous extracellular matrix
0.35	GO:0060205	cytoplasmic vesicle lumen
0.34	GO:0044420	extracellular matrix component
0.34	GO:0005634	nucleus
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P15696|IFNT1_BOVIN
Interferon tau-1
Search

0.97	Interferon omega

0.78	GO:0051607	defense response to virus
0.76	GO:0010469	regulation of receptor activity
0.56	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein
0.56	GO:0002323	natural killer cell activation involved in immune response
0.55	GO:0042100	B cell proliferation
0.55	GO:0002286	T cell activation involved in immune response
0.54	GO:0043330	response to exogenous dsRNA
0.54	GO:0030183	B cell differentiation
0.53	GO:0002250	adaptive immune response
0.53	GO:0006959	humoral immune response

0.80	GO:0005125	cytokine activity
0.79	GO:0005126	cytokine receptor binding
0.50	GO:0032403	protein complex binding
0.45	GO:0005179	hormone activity

0.73	GO:0005615	extracellular space
0.31	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|P15781|PSPB_BOVIN
Pulmonary surfactant-associated protein B
Search

SFTPB

0.96	Pulmonary surfactant-associated protein B

0.69	GO:0006665	sphingolipid metabolic process
0.59	GO:0007585	respiratory gaseous exchange
0.52	GO:0009887	animal organ morphogenesis
0.50	GO:0043085	positive regulation of catalytic activity
0.42	GO:0050828	regulation of liquid surface tension
0.42	GO:0033189	response to vitamin A
0.42	GO:0071732	cellular response to nitric oxide
0.42	GO:0055093	response to hyperoxia
0.41	GO:0070741	response to interleukin-6
0.41	GO:0070849	response to epidermal growth factor

0.53	GO:0001664	G-protein coupled receptor binding
0.51	GO:0008047	enzyme activator activity

0.69	GO:0005764	lysosome
0.59	GO:0097208	alveolar lamellar body
0.56	GO:0005771	multivesicular body
0.52	GO:0005615	extracellular space
0.44	GO:0031906	late endosome lumen
0.41	GO:0045334	clathrin-coated endocytic vesicle
0.39	GO:0005789	endoplasmic reticulum membrane
0.38	GO:0005654	nucleoplasm

sp|P15783|PSPC_BOVIN
Pulmonary surfactant-associated protein C
Search

SFTPC

0.97	Pulmonary surfactant-associated protein C

0.85	GO:0007585	respiratory gaseous exchange
0.40	GO:0050828	regulation of liquid surface tension
0.40	GO:0033189	response to vitamin A
0.39	GO:0071732	cellular response to nitric oxide
0.39	GO:0055093	response to hyperoxia
0.39	GO:0070741	response to interleukin-6
0.39	GO:0051591	response to cAMP
0.39	GO:0071260	cellular response to mechanical stimulus
0.39	GO:0032526	response to retinoic acid
0.39	GO:0051384	response to glucocorticoid

0.53	GO:0042802	identical protein binding
0.36	GO:0046983	protein dimerization activity

0.66	GO:0005576	extracellular region
0.43	GO:0042599	lamellar body
0.42	GO:0005771	multivesicular body
0.41	GO:0031906	late endosome lumen
0.39	GO:0045334	clathrin-coated endocytic vesicle
0.37	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P16068|GCYB1_BOVIN
Guanylate cyclase soluble subunit beta-1
Search

GUCY1B3

0.95	Guanylate cyclase soluble subunit beta-1

0.81	GO:0006182	cGMP biosynthetic process
0.61	GO:0035556	intracellular signal transduction
0.56	GO:0099555	trans-synaptic signaling by nitric oxide, modulating synaptic transmission
0.41	GO:0071732	cellular response to nitric oxide
0.36	GO:0006171	cAMP biosynthetic process
0.35	GO:0008015	blood circulation

0.81	GO:0004383	guanylate cyclase activity
0.62	GO:0020037	heme binding
0.51	GO:1901265	nucleoside phosphate binding
0.50	GO:0036094	small molecule binding
0.46	GO:0004016	adenylate cyclase activity
0.40	GO:0047805	cytidylate cyclase activity
0.38	GO:0051879	Hsp90 protein binding
0.36	GO:0046982	protein heterodimerization activity
0.35	GO:0097367	carbohydrate derivative binding
0.35	GO:0046872	metal ion binding

0.49	GO:0008074	guanylate cyclase complex, soluble
0.38	GO:0005886	plasma membrane
0.38	GO:0048786	presynaptic active zone

0.81	EC:4.6.1.2	GO:0004383
0.40	KEGG:R00574	GO:0047805

sp|P16116|ALDR_BOVIN
Aldose reductase
Search

AKR1B1

0.39	Aldo-keto reductase

0.54	GO:0044598	doxorubicin metabolic process
0.54	GO:0044597	daunorubicin metabolic process
0.53	GO:0071475	cellular hyperosmotic salinity response
0.53	GO:0055114	oxidation-reduction process
0.49	GO:0003091	renal water homeostasis
0.49	GO:0035809	regulation of urine volume
0.47	GO:0072001	renal system development
0.45	GO:0043066	negative regulation of apoptotic process
0.42	GO:0006061	sorbitol biosynthetic process
0.41	GO:0090420	naphthalene-containing compound metabolic process

0.55	GO:0004032	alditol:NADP+ 1-oxidoreductase activity
0.55	GO:0043795	glyceraldehyde oxidoreductase activity
0.36	GO:0047006	17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity
0.35	GO:0047718	indanol dehydrogenase activity
0.35	GO:0001758	retinal dehydrogenase activity
0.34	GO:0045550	geranylgeranyl reductase activity
0.33	GO:0009055	electron transfer activity
0.33	GO:0005515	protein binding

0.45	GO:0005654	nucleoplasm
0.45	GO:0005829	cytosol
0.42	GO:0097454	Schwann cell microvillus
0.41	GO:0033010	paranodal junction
0.40	GO:0043220	Schmidt-Lanterman incisure
0.40	GO:0042629	mast cell granule
0.39	GO:0032838	plasma membrane bounded cell projection cytoplasm
0.39	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle

0.55	EC:1.1.1.21	GO:0004032
0.55	KEGG:R02820	GO:0004032

sp|P16368|TIMP2_BOVIN
Metalloproteinase inhibitor 2
Search

TIMP2

0.92	Tissue inhibitor of metalloproteinase 2

0.76	GO:0010951	negative regulation of endopeptidase activity
0.50	GO:1905049	negative regulation of metallopeptidase activity
0.48	GO:0051045	negative regulation of membrane protein ectodomain proteolysis
0.45	GO:0034097	response to cytokine
0.43	GO:0009725	response to hormone
0.42	GO:0032487	regulation of Rap protein signal transduction
0.42	GO:0030814	regulation of cAMP metabolic process
0.41	GO:0051349	positive regulation of lyase activity
0.41	GO:0031281	positive regulation of cyclase activity
0.41	GO:0045664	regulation of neuron differentiation

0.85	GO:0008191	metalloendopeptidase inhibitor activity
0.51	GO:0002020	protease binding
0.42	GO:0098770	FBXO family protein binding
0.42	GO:0005178	integrin binding
0.42	GO:0008270	zinc ion binding
0.37	GO:0008047	enzyme activator activity
0.36	GO:0008237	metallopeptidase activity

0.66	GO:0005576	extracellular region
0.40	GO:0030426	growth cone
0.40	GO:0009986	cell surface
0.39	GO:0043025	neuronal cell body
0.37	GO:1904724	tertiary granule lumen
0.37	GO:0035580	specific granule lumen
0.37	GO:1904813	ficolin-1-rich granule lumen
0.34	GO:0005634	nucleus

sp|P16386|LIPS_BOVIN
Hormone-sensitive lipase
Search

LIPE

0.88	Hormone-sensitive lipase variant B

0.83	GO:0008203	cholesterol metabolic process
0.72	GO:0016042	lipid catabolic process
0.57	GO:0046339	diacylglycerol metabolic process
0.54	GO:0006641	triglyceride metabolic process
0.52	GO:0001676	long-chain fatty acid metabolic process
0.49	GO:0072329	monocarboxylic acid catabolic process
0.43	GO:0006363	termination of RNA polymerase I transcription
0.42	GO:0006361	transcription initiation from RNA polymerase I promoter
0.36	GO:0007565	female pregnancy
0.35	GO:0019236	response to pheromone

0.75	GO:0016298	lipase activity
0.52	GO:0019901	protein kinase binding
0.49	GO:0052689	carboxylic ester hydrolase activity
0.46	GO:0017171	serine hydrolase activity
0.43	GO:0042134	rRNA primary transcript binding

0.55	GO:0005811	lipid droplet
0.49	GO:0005829	cytosol
0.43	GO:0005901	caveola
0.37	GO:0005634	nucleus
0.37	GO:0005739	mitochondrion
0.34	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane

0.75	EC:3.1.1	GO:0016298
0.49	KEGG:R00630	GO:0052689

sp|P16586|PDE6C_BOVIN
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'
Search

PDE6C

0.56	Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'

0.60	GO:0007165	signal transduction
0.60	GO:0060041	retina development in camera-type eye
0.59	GO:0048593	camera-type eye morphogenesis
0.59	GO:0007601	visual perception
0.56	GO:0042462	eye photoreceptor cell development
0.54	GO:0009583	detection of light stimulus
0.46	GO:0051480	regulation of cytosolic calcium ion concentration
0.45	GO:0045494	photoreceptor cell maintenance
0.44	GO:0046037	GMP metabolic process
0.43	GO:0048598	embryonic morphogenesis

0.79	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.54	GO:0046872	metal ion binding
0.40	GO:0030553	cGMP binding

0.40	GO:0001750	photoreceptor outer segment
0.35	GO:0005886	plasma membrane
0.33	GO:0098588	bounding membrane of organelle
0.30	GO:0044425	membrane part

0.79

GO:0004114

sp|P17248|SYWC_BOVIN
Tryptophan--tRNA ligase, cytoplasmic
Search

WARS

0.57	Tryptophanyl-tRNA synthetase

0.78	GO:0006436	tryptophanyl-tRNA aminoacylation
0.58	GO:0010835	regulation of protein ADP-ribosylation
0.54	GO:0045765	regulation of angiogenesis
0.53	GO:0006469	negative regulation of protein kinase activity
0.52	GO:0031334	positive regulation of protein complex assembly
0.49	GO:0010628	positive regulation of gene expression
0.39	GO:0001525	angiogenesis
0.34	GO:0008285	negative regulation of cell proliferation

0.78	GO:0004830	tryptophan-tRNA ligase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0019210	kinase inhibitor activity
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0019901	protein kinase binding
0.51	GO:0019904	protein domain specific binding
0.51	GO:0042803	protein homodimerization activity

0.49	GO:0005737	cytoplasm
0.44	GO:0005634	nucleus
0.44	GO:0043234	protein complex
0.36	GO:0070062	extracellular exosome

0.78

EC:6.1.1.2

GO:0004830

sp|P17289|TY3H_BOVIN
Tyrosine 3-monooxygenase
Search

0.88	Tyrosine hydroxylase

0.79	GO:0042423	catecholamine biosynthetic process
0.68	GO:0009072	aromatic amino acid family metabolic process
0.61	GO:0007617	mating behavior
0.59	GO:0042417	dopamine metabolic process
0.56	GO:0007625	grooming behavior
0.56	GO:0071625	vocalization behavior
0.56	GO:0035176	social behavior
0.55	GO:0042414	epinephrine metabolic process
0.55	GO:0060416	response to growth hormone
0.53	GO:0001963	synaptic transmission, dopaminergic

0.82	GO:0004511	tyrosine 3-monooxygenase activity
0.62	GO:0005506	iron ion binding
0.46	GO:0019899	enzyme binding
0.40	GO:0004510	tryptophan 5-monooxygenase activity
0.38	GO:0034617	tetrahydrobiopterin binding
0.38	GO:0035240	dopamine binding
0.36	GO:0019825	oxygen binding
0.36	GO:0019904	protein domain specific binding
0.36	GO:0016597	amino acid binding
0.34	GO:0005179	hormone activity

0.53	GO:0033162	melanosome membrane
0.53	GO:0005790	smooth endoplasmic reticulum
0.52	GO:0043204	perikaryon
0.50	GO:0030424	axon
0.48	GO:0009898	cytoplasmic side of plasma membrane
0.42	GO:0005634	nucleus
0.37	GO:0043679	axon terminus
0.37	GO:0008021	synaptic vesicle
0.37	GO:0030425	dendrite
0.35	GO:0070852	cell body fiber

0.82

EC:1.14.16.2

GO:0004511

sp|P17305|STP1_BOVIN
Spermatid nuclear transition protein 1
Search

TNP1

0.97	Spermatid nuclear transition protein 1

0.80	GO:0007283	spermatogenesis
0.74	GO:0000012	single strand break repair
0.73	GO:0031498	chromatin disassembly
0.73	GO:0032986	protein-DNA complex disassembly
0.72	GO:0030317	flagellated sperm motility
0.72	GO:0010954	positive regulation of protein processing
0.70	GO:0006997	nucleus organization
0.68	GO:0006342	chromatin silencing
0.68	GO:0043486	histone exchange
0.68	GO:0007281	germ cell development

0.55	GO:0003677	DNA binding
0.35	GO:0005515	protein binding

0.75	GO:0000786	nucleosome
0.62	GO:0000790	nuclear chromatin
0.57	GO:0001673	male germ cell nucleus

sp|P17322|EDN1_BOVIN
Endothelin-1
Search

EDN1

0.95	Preproendothelin

0.85	GO:0019229	regulation of vasoconstriction
0.69	GO:0042310	vasoconstriction
0.68	GO:0060584	regulation of prostaglandin-endoperoxide synthase activity
0.67	GO:0003100	regulation of systemic arterial blood pressure by endothelin
0.66	GO:0014820	tonic smooth muscle contraction
0.65	GO:0014821	phasic smooth muscle contraction
0.65	GO:0010460	positive regulation of heart rate
0.65	GO:0042313	protein kinase C deactivation
0.64	GO:0030185	nitric oxide transport
0.64	GO:0046457	prostanoid biosynthetic process

0.68	GO:0031708	endothelin B receptor binding
0.65	GO:0031707	endothelin A receptor binding
0.59	GO:0005179	hormone activity
0.57	GO:0005125	cytokine activity

0.66	GO:0005576	extracellular region
0.44	GO:0048237	rough endoplasmic reticulum lumen
0.43	GO:0033093	Weibel-Palade body
0.42	GO:0045178	basal part of cell
0.35	GO:0030133	transport vesicle
0.30	GO:0031224	intrinsic component of membrane

0.63

EC:1.97.1

GO:0051353

sp|P17404|LECT1_BOVIN
Leukocyte cell-derived chemotaxin 1
Search

CNMD

0.97	Leukocyte cell-derived chemotaxin 1

0.63	GO:0016525	negative regulation of angiogenesis
0.44	GO:0051216	cartilage development
0.41	GO:0030154	cell differentiation
0.41	GO:0007585	respiratory gaseous exchange
0.39	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway
0.39	GO:0001937	negative regulation of endothelial cell proliferation
0.39	GO:0003158	endothelium development
0.37	GO:0000902	cell morphogenesis
0.36	GO:0006029	proteoglycan metabolic process
0.36	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules

0.35

GO:0005509

calcium ion binding

0.42	GO:0005578	proteinaceous extracellular matrix
0.40	GO:0012505	endomembrane system
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P17453|BPI_BOVIN
Bactericidal permeability-increasing protein
Search

BPI

0.89	bactericidal permeability-increasing protein-like

0.81	GO:0050829	defense response to Gram-negative bacterium
0.72	GO:0006955	immune response
0.58	GO:0032720	negative regulation of tumor necrosis factor production
0.58	GO:0043030	regulation of macrophage activation
0.58	GO:0032717	negative regulation of interleukin-8 production
0.57	GO:0032675	regulation of interleukin-6 production
0.55	GO:0002695	negative regulation of leukocyte activation
0.48	GO:0006953	acute-phase response
0.41	GO:0071222	cellular response to lipopolysaccharide
0.41	GO:0002274	myeloid leukocyte activation

0.80	GO:0001530	lipopolysaccharide binding
0.41	GO:0070891	lipoteichoic acid binding
0.41	GO:0071723	lipopeptide binding
0.37	GO:0005102	receptor binding
0.35	GO:0005200	structural constituent of cytoskeleton
0.35	GO:0051539	4 iron, 4 sulfur cluster binding
0.34	GO:0003924	GTPase activity
0.34	GO:0005525	GTP binding
0.33	GO:0008188	neuropeptide receptor activity

0.69	GO:0005615	extracellular space
0.38	GO:0009986	cell surface
0.37	GO:1903561	extracellular vesicle
0.37	GO:0005737	cytoplasm
0.36	GO:0031983	vesicle lumen
0.35	GO:0035770	ribonucleoprotein granule
0.35	GO:0097708	intracellular vesicle
0.34	GO:0005874	microtubule
0.34	GO:0012505	endomembrane system
0.34	GO:0070013	intracellular organelle lumen

sp|P17599|SYN1_BOVIN
Synapsin-1
Search

SYN1

0.92	Synapsin IIb

0.82	GO:0099643	signal release from synapse
0.82	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.76	GO:0006836	neurotransmitter transport
0.72	GO:0001505	regulation of neurotransmitter levels
0.69	GO:0051649	establishment of localization in cell
0.58	GO:0097479	synaptic vesicle localization
0.39	GO:0099177	regulation of trans-synaptic signaling
0.38	GO:1902803	regulation of synaptic vesicle transport
0.37	GO:0098693	regulation of synaptic vesicle cycle
0.37	GO:0051588	regulation of neurotransmitter transport

0.56	GO:0019901	protein kinase binding
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0048306	calcium-dependent protein binding
0.42	GO:0003779	actin binding
0.35	GO:0046983	protein dimerization activity
0.34	GO:0005215	transporter activity
0.33	GO:0046872	metal ion binding

0.82	GO:0008021	synaptic vesicle
0.62	GO:0099501	exocytic vesicle membrane
0.60	GO:0014069	postsynaptic density
0.60	GO:0000795	synaptonemal complex
0.60	GO:0043209	myelin sheath
0.59	GO:0048786	presynaptic active zone
0.57	GO:0030424	axon
0.51	GO:0005856	cytoskeleton
0.42	GO:0030054	cell junction
0.42	GO:0043679	axon terminus

sp|P17667|MYF5_BOVIN
Myogenic factor 5
Search

MYF5

0.93	Myogenic factor

0.80	GO:0007517	muscle organ development
0.62	GO:0014706	striated muscle tissue development
0.61	GO:0001502	cartilage condensation
0.59	GO:0043010	camera-type eye development
0.59	GO:0001756	somitogenesis
0.59	GO:0001952	regulation of cell-matrix adhesion
0.59	GO:0048704	embryonic skeletal system morphogenesis
0.58	GO:0001503	ossification
0.57	GO:0006366	transcription by RNA polymerase II
0.57	GO:0030198	extracellular matrix organization

0.68	GO:0046983	protein dimerization activity
0.60	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.54	GO:0003677	DNA binding
0.50	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.49	GO:0001067	regulatory region nucleic acid binding
0.42	GO:0035257	nuclear hormone receptor binding
0.40	GO:0031625	ubiquitin protein ligase binding
0.40	GO:0003713	transcription coactivator activity
0.40	GO:0003682	chromatin binding

0.61	GO:0005634	nucleus
0.53	GO:0070013	intracellular organelle lumen
0.47	GO:0044446	intracellular organelle part
0.41	GO:0005667	transcription factor complex
0.41	GO:0030016	myofibril
0.38	GO:0005829	cytosol
0.38	GO:0005694	chromosome

sp|P17690|APOH_BOVIN
Beta-2-glycoprotein 1
Search

APOH

0.92	Apolipoprotein H

0.86	GO:0007597	blood coagulation, intrinsic pathway
0.86	GO:0034392	negative regulation of smooth muscle cell apoptotic process
0.85	GO:0051918	negative regulation of fibrinolysis
0.85	GO:0051006	positive regulation of lipoprotein lipase activity
0.85	GO:0033033	negative regulation of myeloid cell apoptotic process
0.84	GO:0031639	plasminogen activation
0.83	GO:0001937	negative regulation of endothelial cell proliferation
0.83	GO:0010596	negative regulation of endothelial cell migration
0.83	GO:1900047	negative regulation of hemostasis
0.82	GO:0050819	negative regulation of coagulation

0.86	GO:0060230	lipoprotein lipase activator activity
0.72	GO:0005543	phospholipid binding
0.71	GO:0042802	identical protein binding
0.54	GO:0008201	heparin binding
0.36	GO:0004875	complement receptor activity
0.36	GO:0030246	carbohydrate binding
0.35	GO:0001848	complement binding
0.34	GO:0046983	protein dimerization activity
0.34	GO:0030414	peptidase inhibitor activity
0.33	GO:0005509	calcium ion binding

0.84	GO:0042627	chylomicron
0.83	GO:0034361	very-low-density lipoprotein particle
0.83	GO:0034364	high-density lipoprotein particle
0.72	GO:0009986	cell surface
0.71	GO:0031012	extracellular matrix
0.44	GO:0070062	extracellular exosome
0.43	GO:0031089	platelet dense granule lumen
0.42	GO:0043296	apical junction complex
0.35	GO:0072562	blood microparticle
0.35	GO:0005886	plasma membrane

0.32

GO:0004222

sp|P17694|NDUS2_BOVIN
NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial
Search

NDUFS2

0.42	NADH dehydrogenase iron-sulfur protein 2

0.53	GO:0055114	oxidation-reduction process
0.48	GO:0006979	response to oxidative stress
0.44	GO:0006119	oxidative phosphorylation
0.35	GO:0032981	mitochondrial respiratory chain complex I assembly
0.34	GO:0007166	cell surface receptor signaling pathway

0.72	GO:0048038	quinone binding
0.68	GO:0051287	NAD binding
0.67	GO:0016651	oxidoreductase activity, acting on NAD(P)H
0.51	GO:0031625	ubiquitin protein ligase binding
0.39	GO:0051539	4 iron, 4 sulfur cluster binding
0.36	GO:0046872	metal ion binding
0.34	GO:0004888	transmembrane signaling receptor activity
0.33	GO:0009055	electron transfer activity

0.52	GO:0005747	mitochondrial respiratory chain complex I
0.47	GO:0005654	nucleoplasm
0.34	GO:0005759	mitochondrial matrix
0.30	GO:0031224	intrinsic component of membrane

0.67

GO:0016651

sp|P17697|CLUS_BOVIN
Clusterin
Search

CLU

0.96

Clusterin

0.74	GO:0032463	negative regulation of protein homooligomerization
0.74	GO:1902847	regulation of neuronal signal transduction
0.74	GO:1905895	negative regulation of cellular response to tunicamycin
0.74	GO:1905892	negative regulation of cellular response to thapsigargin
0.74	GO:1902998	positive regulation of neurofibrillary tangle assembly
0.73	GO:0061518	microglial cell proliferation
0.73	GO:1902949	positive regulation of tau-protein kinase activity
0.72	GO:2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.72	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
0.72	GO:1905907	negative regulation of amyloid fibril formation

0.72	GO:0051787	misfolded protein binding
0.69	GO:0050750	low-density lipoprotein particle receptor binding
0.68	GO:0001540	amyloid-beta binding
0.66	GO:0031625	ubiquitin protein ligase binding
0.60	GO:0032403	protein complex binding
0.42	GO:0016887	ATPase activity
0.39	GO:0051087	chaperone binding
0.38	GO:0097099	structural constituent of albumen
0.37	GO:0047485	protein N-terminus binding

0.74	GO:0034366	spherical high-density lipoprotein particle
0.71	GO:0097418	neurofibrillary tangle
0.71	GO:0097440	apical dendrite
0.70	GO:0106003	amyloid-beta complex
0.65	GO:0048471	perinuclear region of cytoplasm
0.62	GO:0031012	extracellular matrix
0.60	GO:0009986	cell surface
0.56	GO:0042583	chromaffin granule
0.52	GO:0005739	mitochondrion
0.47	GO:0005783	endoplasmic reticulum

0.42

GO:0016887

sp|P17810|PRPH2_BOVIN
Peripherin-2
Search

PRPH2

0.97	Retinal degeneration, slow (Retinitis pigmentosa 7)

0.78	GO:0007601	visual perception
0.55	GO:0060041	retina development in camera-type eye
0.44	GO:0007166	cell surface receptor signaling pathway
0.40	GO:0007155	cell adhesion
0.36	GO:1903525	regulation of membrane tubulation
0.35	GO:0009645	response to low light intensity stimulus
0.35	GO:0051289	protein homotetramerization
0.34	GO:0051258	protein polymerization

0.34	GO:0042803	protein homodimerization activity
0.34	GO:0015631	tubulin binding

0.56	GO:0001750	photoreceptor outer segment
0.43	GO:0005887	integral component of plasma membrane
0.35	GO:0055037	recycling endosome
0.35	GO:0005795	Golgi stack
0.34	GO:0005783	endoplasmic reticulum
0.33	GO:0043234	protein complex

sp|P17870|ARRB1_BOVIN
Beta-arrestin-1
Search

ARRB1

0.95	Beta-arrestin-1

0.61	GO:0007165	signal transduction
0.56	GO:0045746	negative regulation of Notch signaling pathway
0.54	GO:0043393	regulation of protein binding
0.54	GO:0090240	positive regulation of histone H4 acetylation
0.54	GO:0002031	G-protein coupled receptor internalization
0.54	GO:0002092	positive regulation of receptor internalization
0.53	GO:0032717	negative regulation of interleukin-8 production
0.53	GO:0043149	stress fiber assembly
0.53	GO:0032715	negative regulation of interleukin-6 production
0.53	GO:0035025	positive regulation of Rho protein signal transduction

0.54	GO:1990763	arrestin family protein binding
0.54	GO:0031701	angiotensin receptor binding
0.53	GO:0031434	mitogen-activated protein kinase kinase binding
0.53	GO:0005159	insulin-like growth factor receptor binding
0.53	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.49	GO:0031625	ubiquitin protein ligase binding
0.48	GO:0005096	GTPase activator activity
0.48	GO:0044212	transcription regulatory region DNA binding
0.47	GO:0008134	transcription factor binding
0.40	GO:0035612	AP-2 adaptor complex binding

0.54	GO:0031143	pseudopodium
0.49	GO:0016604	nuclear body
0.47	GO:0031410	cytoplasmic vesicle
0.46	GO:0000785	chromatin
0.45	GO:0005829	cytosol
0.40	GO:0005905	clathrin-coated pit
0.38	GO:0043197	dendritic spine
0.38	GO:0014069	postsynaptic density
0.38	GO:0016323	basolateral plasma membrane
0.37	GO:0045211	postsynaptic membrane

0.36

EC:2.3.1.48

GO:0004402

sp|P18130|ADA1A_BOVIN
Alpha-1A adrenergic receptor
Search

ADRA1A

0.93	Alpha-1a adrenoceptor transcript variant 1

0.85	GO:0071875	adrenergic receptor signaling pathway
0.79	GO:0055117	regulation of cardiac muscle contraction
0.79	GO:0019229	regulation of vasoconstriction
0.70	GO:0001994	norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure
0.67	GO:0045987	positive regulation of smooth muscle contraction
0.66	GO:0001985	negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure
0.65	GO:1903524	positive regulation of blood circulation
0.65	GO:1903995	regulation of non-membrane spanning protein tyrosine kinase activity
0.64	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.63	GO:0003057	regulation of the force of heart contraction by chemical signal

0.85	GO:0004935	adrenergic receptor activity
0.58	GO:0046982	protein heterodimerization activity

0.61	GO:0031965	nuclear membrane
0.56	GO:0005886	plasma membrane
0.42	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

sp|P18203|FKB1A_BOVIN
Peptidyl-prolyl cis-trans isomerase FKBP1A
Search

0.60	Peptidyl-prolyl cis-trans isomerase FKBP1A

0.86	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity
0.85	GO:1990000	amyloid fibril formation
0.85	GO:0007183	SMAD protein complex assembly
0.85	GO:0060347	heart trabecula formation
0.85	GO:0031000	response to caffeine
0.84	GO:1902991	regulation of amyloid precursor protein catabolic process
0.83	GO:0032925	regulation of activin receptor signaling pathway
0.83	GO:0042098	T cell proliferation
0.82	GO:0055010	ventricular cardiac muscle tissue morphogenesis
0.80	GO:0032092	positive regulation of protein binding

0.85	GO:0048185	activin binding
0.81	GO:0005528	FK506 binding
0.80	GO:0044325	ion channel binding
0.80	GO:0046332	SMAD binding
0.80	GO:0019855	calcium channel inhibitor activity
0.73	GO:0034713	type I transforming growth factor beta receptor binding
0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.71	GO:0030544	Hsp70 protein binding
0.71	GO:0042803	protein homodimerization activity
0.60	GO:0019899	enzyme binding

0.88	GO:1990425	ryanodine receptor complex
0.81	GO:0031312	extrinsic component of organelle membrane
0.79	GO:0030018	Z disc
0.76	GO:0098562	cytoplasmic side of membrane
0.75	GO:0014802	terminal cisterna
0.72	GO:0070062	extracellular exosome
0.69	GO:0043679	axon terminus
0.69	GO:0005829	cytosol

0.72

GO:0003755

sp|P18246|CXA1_BOVIN
Gap junction alpha-1 protein
Search

GJA1

0.64	Gap junction alpha-1 protein (Fragment)

0.79	GO:0007507	heart development
0.75	GO:0007267	cell-cell signaling
0.55	GO:0010644	cell communication by electrical coupling
0.55	GO:0055085	transmembrane transport
0.52	GO:0060156	milk ejection reflex
0.51	GO:0010643	cell communication by chemical coupling
0.50	GO:0060373	regulation of ventricular cardiac muscle cell membrane depolarization
0.50	GO:0030308	negative regulation of cell growth
0.50	GO:0060371	regulation of atrial cardiac muscle cell membrane depolarization
0.49	GO:0002070	epithelial cell maturation

0.57	GO:0022857	transmembrane transporter activity
0.48	GO:0097110	scaffold protein binding
0.48	GO:1990782	protein tyrosine kinase binding
0.47	GO:0048487	beta-tubulin binding
0.44	GO:0004871	signal transducer activity
0.44	GO:0005102	receptor binding
0.39	GO:0030165	PDZ domain binding
0.38	GO:0071253	connexin binding
0.38	GO:0017124	SH3 domain binding
0.38	GO:0097718	disordered domain specific binding

0.83	GO:0005922	connexin complex
0.56	GO:0014704	intercalated disc
0.48	GO:0016328	lateral plasma membrane
0.47	GO:0005913	cell-cell adherens junction
0.47	GO:0016324	apical plasma membrane
0.46	GO:0005654	nucleoplasm
0.46	GO:0043292	contractile fiber
0.46	GO:0005882	intermediate filament
0.44	GO:0012505	endomembrane system
0.43	GO:0005739	mitochondrion

sp|P18341|TGFB1_BOVIN
Transforming growth factor beta-1
Search

TGFB1

0.92	Transforming growth factor beta

0.79	GO:0016049	cell growth
0.77	GO:1900126	negative regulation of hyaluronan biosynthetic process
0.76	GO:1901664	regulation of NAD+ ADP-ribosyltransferase activity
0.76	GO:0043932	ossification involved in bone remodeling
0.75	GO:0048298	positive regulation of isotype switching to IgA isotypes
0.75	GO:0007182	common-partner SMAD protein phosphorylation
0.75	GO:0010936	negative regulation of macrophage cytokine production
0.75	GO:0007183	SMAD protein complex assembly
0.75	GO:0010763	positive regulation of fibroblast migration
0.74	GO:0032740	positive regulation of interleukin-17 production

0.84	GO:0005160	transforming growth factor beta receptor binding
0.75	GO:0008083	growth factor activity
0.71	GO:0003823	antigen binding
0.58	GO:0043539	protein serine/threonine kinase activator activity
0.53	GO:0042802	identical protein binding
0.51	GO:0019899	enzyme binding
0.48	GO:0005125	cytokine activity
0.41	GO:0047485	protein N-terminus binding
0.39	GO:0046982	protein heterodimerization activity
0.34	GO:0050431	transforming growth factor beta binding

0.72	GO:0005615	extracellular space
0.63	GO:0009986	cell surface
0.60	GO:0005902	microvillus
0.56	GO:0005578	proteinaceous extracellular matrix
0.53	GO:0005634	nucleus
0.44	GO:0005737	cytoplasm
0.40	GO:0043025	neuronal cell body
0.40	GO:0030424	axon
0.38	GO:0097708	intracellular vesicle
0.37	GO:0012505	endomembrane system

sp|P18493|PARP1_BOVIN
Poly [ADP-ribose] polymerase 1
Search

PARP1

0.57	Poly [ADP-ribose] polymerase

0.83	GO:0006471	protein ADP-ribosylation
0.63	GO:1990966	ATP generation from poly-ADP-D-ribose
0.62	GO:1903518	positive regulation of single strand break repair
0.61	GO:2001170	negative regulation of ATP biosynthetic process
0.59	GO:0043504	mitochondrial DNA repair
0.57	GO:0018209	peptidyl-serine modification
0.57	GO:0032869	cellular response to insulin stimulus
0.56	GO:0034644	cellular response to UV
0.53	GO:0006915	apoptotic process
0.53	GO:0006302	double-strand break repair

0.81	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.65	GO:0051287	NAD binding
0.64	GO:1990404	protein ADP-ribosylase activity
0.62	GO:0008270	zinc ion binding
0.57	GO:0047485	protein N-terminus binding
0.55	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.54	GO:0003677	DNA binding
0.54	GO:0019901	protein kinase binding
0.53	GO:0001067	regulatory region nucleic acid binding
0.52	GO:0042802	identical protein binding

0.59	GO:0005634	nucleus
0.52	GO:0005667	transcription factor complex
0.51	GO:0032993	protein-DNA complex
0.49	GO:0070013	intracellular organelle lumen
0.49	GO:0012505	endomembrane system
0.46	GO:0031967	organelle envelope
0.45	GO:0005739	mitochondrion
0.45	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

0.81

EC:2.4.2.30

GO:0003950

sp|P18892|BT1A1_BOVIN
Butyrophilin subfamily 1 member A1
Search

BTN1A1

0.81	Erythroblast membrane associated protein (Scianna blood group)

0.43	GO:0051241	negative regulation of multicellular organismal process
0.43	GO:0046007	negative regulation of activated T cell proliferation
0.42	GO:0050709	negative regulation of protein secretion
0.41	GO:0050707	regulation of cytokine secretion
0.41	GO:0031324	negative regulation of cellular metabolic process
0.41	GO:0045595	regulation of cell differentiation
0.41	GO:0046598	positive regulation of viral entry into host cell
0.40	GO:2000026	regulation of multicellular organismal development
0.40	GO:0046597	negative regulation of viral entry into host cell
0.40	GO:0016567	protein ubiquitination

0.43	GO:0008270	zinc ion binding
0.40	GO:0004842	ubiquitin-protein transferase activity
0.40	GO:0008134	transcription factor binding
0.39	GO:0035035	histone acetyltransferase binding
0.38	GO:0051427	hormone receptor binding
0.38	GO:0019904	protein domain specific binding
0.38	GO:0061659	ubiquitin-like protein ligase activity
0.37	GO:0016874	ligase activity
0.35	GO:0042802	identical protein binding
0.35	GO:0004872	receptor activity

0.40	GO:0005829	cytosol
0.38	GO:0005615	extracellular space
0.38	GO:0005634	nucleus
0.37	GO:0009986	cell surface
0.37	GO:0005794	Golgi apparatus
0.36	GO:0005886	plasma membrane
0.36	GO:0070013	intracellular organelle lumen
0.35	GO:0043232	intracellular non-membrane-bounded organelle
0.35	GO:0044446	intracellular organelle part
0.34	GO:0005739	mitochondrion

0.37	EC:6	GO:0016874
0.40	KEGG:R03876	GO:0004842

sp|P18902|RET4_BOVIN
Retinol-binding protein 4
Search

RBP4

0.97	Plasma retinol binding protein 4

0.86	GO:0034633	retinol transport
0.55	GO:0032526	response to retinoic acid
0.55	GO:0030277	maintenance of gastrointestinal epithelium
0.54	GO:0042572	retinol metabolic process
0.54	GO:0032024	positive regulation of insulin secretion
0.52	GO:0001654	eye development
0.51	GO:0042593	glucose homeostasis
0.48	GO:0019319	hexose biosynthetic process
0.47	GO:0006006	glucose metabolic process
0.39	GO:0001889	liver development

0.86	GO:0034632	retinol transmembrane transporter activity
0.83	GO:0005501	retinoid binding
0.54	GO:0043178	alcohol binding
0.46	GO:0019842	vitamin binding
0.36	GO:0046982	protein heterodimerization activity
0.34	GO:0019904	protein domain specific binding
0.33	GO:0005102	receptor binding

0.50	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.36	GO:0060418	yolk plasma
0.34	GO:0043234	protein complex
0.34	GO:0030136	clathrin-coated vesicle
0.34	GO:0033165	interphotoreceptor matrix
0.33	GO:0005829	cytosol

sp|P18915|CAH6_BOVIN
Carbonic anhydrase 6
Search

CA6

0.88	Stress-inducible intra-cellular carbonic anhydrase isozyme VI

0.69	GO:0006730	one-carbon metabolic process
0.52	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste
0.38	GO:0097369	sodium ion import
0.37	GO:0006885	regulation of pH
0.36	GO:0015701	bicarbonate transport
0.35	GO:0002009	morphogenesis of an epithelium
0.34	GO:0046903	secretion
0.33	GO:2001225	regulation of chloride transport
0.33	GO:0032230	positive regulation of synaptic transmission, GABAergic
0.33	GO:0032846	positive regulation of homeostatic process

0.74	GO:0004089	carbonate dehydratase activity
0.60	GO:0008270	zinc ion binding

0.46	GO:0005615	extracellular space
0.40	GO:0005829	cytosol
0.37	GO:0009897	external side of plasma membrane
0.37	GO:1903561	extracellular vesicle
0.35	GO:0031225	anchored component of membrane
0.35	GO:0043209	myelin sheath
0.34	GO:0043231	intracellular membrane-bounded organelle
0.33	GO:0031526	brush border membrane
0.33	GO:0030667	secretory granule membrane
0.33	GO:0016324	apical plasma membrane

0.74

EC:4.2.1.1

GO:0004089

sp|P18917|PLRP4_BOVIN
Placental prolactin-related protein 4
Search

0.81	Chorionic somatomammotropin hormone 2

0.76	GO:0010469	regulation of receptor activity
0.44	GO:0045723	positive regulation of fatty acid biosynthetic process
0.44	GO:0030072	peptide hormone secretion
0.43	GO:0050878	regulation of body fluid levels
0.42	GO:0010751	negative regulation of nitric oxide mediated signal transduction
0.42	GO:0043066	negative regulation of apoptotic process
0.41	GO:0030879	mammary gland development
0.41	GO:0001825	blastocyst formation
0.40	GO:0033685	negative regulation of luteinizing hormone secretion
0.40	GO:0010628	positive regulation of gene expression

0.79	GO:0005179	hormone activity
0.46	GO:0005148	prolactin receptor binding
0.33	GO:0046872	metal ion binding

0.66	GO:0005576	extracellular region
0.30	GO:0016020	membrane

sp|P19034|APOC2_BOVIN
Apolipoprotein C-II
Search

APOC2

0.97	Apolipoprotein C-II

0.74	GO:0006869	lipid transport
0.73	GO:0043085	positive regulation of catalytic activity
0.68	GO:0060697	positive regulation of phospholipid catabolic process
0.68	GO:0010915	regulation of very-low-density lipoprotein particle clearance
0.67	GO:0071830	triglyceride-rich lipoprotein particle clearance
0.67	GO:0034384	high-density lipoprotein particle clearance
0.67	GO:0010985	negative regulation of lipoprotein particle clearance
0.66	GO:0032375	negative regulation of cholesterol transport
0.66	GO:0048261	negative regulation of receptor-mediated endocytosis
0.65	GO:0051004	regulation of lipoprotein lipase activity

0.75	GO:0008047	enzyme activator activity
0.66	GO:0043274	phospholipase binding
0.64	GO:0055102	lipase inhibitor activity
0.57	GO:0042803	protein homodimerization activity
0.55	GO:0008289	lipid binding

0.86	GO:0042627	chylomicron
0.77	GO:0034362	low-density lipoprotein particle
0.75	GO:0034361	very-low-density lipoprotein particle
0.74	GO:0034364	high-density lipoprotein particle
0.67	GO:0034363	intermediate-density lipoprotein particle
0.38	GO:0070062	extracellular exosome
0.38	GO:0005769	early endosome

sp|P19035|APOC3_BOVIN
Apolipoprotein C-III
Search

APOC3

0.97	Apolipoprotein C-III

0.79	GO:0010987	negative regulation of high-density lipoprotein particle clearance
0.77	GO:0010897	negative regulation of triglyceride catabolic process
0.77	GO:0010989	negative regulation of low-density lipoprotein particle clearance
0.77	GO:0010915	regulation of very-low-density lipoprotein particle clearance
0.76	GO:0051005	negative regulation of lipoprotein lipase activity
0.75	GO:0060621	negative regulation of cholesterol import
0.75	GO:0042157	lipoprotein metabolic process
0.74	GO:0006869	lipid transport
0.74	GO:0010903	negative regulation of very-low-density lipoprotein particle remodeling
0.74	GO:0071830	triglyceride-rich lipoprotein particle clearance

0.77	GO:0070653	high-density lipoprotein particle receptor binding
0.72	GO:0055102	lipase inhibitor activity
0.72	GO:0008289	lipid binding
0.47	GO:0043168	anion binding
0.38	GO:0043178	alcohol binding
0.33	GO:0097159	organic cyclic compound binding

0.76	GO:0034363	intermediate-density lipoprotein particle
0.75	GO:0034366	spherical high-density lipoprotein particle
0.74	GO:0042627	chylomicron
0.74	GO:0034361	very-low-density lipoprotein particle
0.61	GO:0031012	extracellular matrix
0.38	GO:0070062	extracellular exosome
0.38	GO:0005769	early endosome
0.35	GO:0005829	cytosol

sp|P19111|PPBI_BOVIN
Intestinal-type alkaline phosphatase
Search

0.47	Intestinal-type alkaline phosphatase

0.68	GO:0016311	dephosphorylation
0.41	GO:0010033	response to organic substance
0.40	GO:0033273	response to vitamin
0.39	GO:0001958	endochondral ossification
0.39	GO:0070887	cellular response to chemical stimulus
0.38	GO:0071495	cellular response to endogenous stimulus
0.37	GO:1901700	response to oxygen-containing compound
0.37	GO:0003006	developmental process involved in reproduction
0.37	GO:0006501	C-terminal protein lipidation
0.37	GO:0046677	response to antibiotic

0.79	GO:0004035	alkaline phosphatase activity
0.45	GO:0002020	protease binding
0.39	GO:0000287	magnesium ion binding
0.38	GO:0008270	zinc ion binding
0.35	GO:0016462	pyrophosphatase activity
0.34	GO:0042803	protein homodimerization activity

0.43	GO:0031225	anchored component of membrane
0.42	GO:0009986	cell surface
0.41	GO:0005886	plasma membrane
0.40	GO:0065010	extracellular membrane-bounded organelle
0.38	GO:0098552	side of membrane
0.37	GO:0030016	myofibril
0.37	GO:0005578	proteinaceous extracellular matrix
0.35	GO:0005903	brush border
0.30	GO:0016021	integral component of membrane

0.79

EC:3.1.3.1

GO:0004035

sp|P19120|HSP7C_BOVIN
Heat shock cognate 71 kDa protein
Search

HSPA8

0.76	Heat shock cognate protein isoform A

0.56	GO:0061740	protein targeting to lysosome involved in chaperone-mediated autophagy
0.55	GO:0061738	late endosomal microautophagy
0.55	GO:0072318	clathrin coat disassembly
0.54	GO:0044829	positive regulation by host of viral genome replication
0.53	GO:0048026	positive regulation of mRNA splicing, via spliceosome
0.51	GO:0051085	chaperone cofactor-dependent protein refolding
0.50	GO:1902904	negative regulation of supramolecular fiber organization
0.50	GO:0031647	regulation of protein stability
0.49	GO:0042026	protein refolding
0.48	GO:0045892	negative regulation of transcription, DNA-templated

0.55	GO:0055131	C3HC4-type RING finger domain binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0001786	phosphatidylserine binding
0.51	GO:0045296	cadherin binding
0.50	GO:0001664	G-protein coupled receptor binding
0.50	GO:0031072	heat shock protein binding
0.50	GO:0031625	ubiquitin protein ligase binding

0.53	GO:0000974	Prp19 complex
0.51	GO:0070062	extracellular exosome
0.51	GO:0043209	myelin sheath
0.50	GO:0005770	late endosome
0.49	GO:0000151	ubiquitin ligase complex
0.46	GO:0005829	cytosol
0.44	GO:0005634	nucleus
0.44	GO:0030529	intracellular ribonucleoprotein complex
0.42	GO:0042470	melanosome
0.38	GO:0043202	lysosomal lumen

sp|P19141|CRBB3_BOVIN
Beta-crystallin B3
Search

CRYBB3

0.97	Beta-crystallin B3

0.74	GO:0007601	visual perception
0.39	GO:0043010	camera-type eye development
0.34	GO:0006468	protein phosphorylation
0.33	GO:0007165	signal transduction

0.81	GO:0005212	structural constituent of eye lens
0.38	GO:0042803	protein homodimerization activity
0.37	GO:0047696	beta-adrenergic receptor kinase activity
0.35	GO:0004703	G-protein coupled receptor kinase activity
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0097367	carbohydrate derivative binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.37

EC:2.7.11.15

GO:0047696

sp|P19159|CSH2_BOVIN
Chorionic somatomammotropin hormone 2
Search

0.85	Chorionic somatomammotropin hormone

0.75	GO:0010469	regulation of receptor activity
0.46	GO:0045723	positive regulation of fatty acid biosynthetic process
0.46	GO:0030072	peptide hormone secretion
0.44	GO:0010628	positive regulation of gene expression
0.44	GO:0007595	lactation
0.43	GO:0043066	negative regulation of apoptotic process
0.42	GO:1903489	positive regulation of lactation
0.41	GO:0010751	negative regulation of nitric oxide mediated signal transduction
0.41	GO:0001825	blastocyst formation
0.40	GO:1902893	regulation of pri-miRNA transcription by RNA polymerase II

0.79	GO:0005179	hormone activity
0.51	GO:0005148	prolactin receptor binding
0.34	GO:0046872	metal ion binding

0.66	GO:0005576	extracellular region
0.35	GO:0005788	endoplasmic reticulum lumen
0.34	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

sp|P19217|ST1E1_BOVIN
Estrogen sulfotransferase
Search

SULT1E1

0.53	Estrogen sulfotransferase

0.53	GO:0051923	sulfation
0.48	GO:0042403	thyroid hormone metabolic process
0.47	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process
0.47	GO:0006068	ethanol catabolic process
0.45	GO:0006805	xenobiotic metabolic process
0.43	GO:0008210	estrogen metabolic process
0.41	GO:0009812	flavonoid metabolic process
0.40	GO:0006706	steroid catabolic process
0.40	GO:0045600	positive regulation of fat cell differentiation
0.39	GO:0030855	epithelial cell differentiation

0.78	GO:0008146	sulfotransferase activity
0.42	GO:0005496	steroid binding
0.35	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding
0.34	GO:0005515	protein binding
0.33	GO:0042562	hormone binding
0.33	GO:0043178	alcohol binding
0.32	GO:0003676	nucleic acid binding

0.39	GO:0005829	cytosol
0.37	GO:0031965	nuclear membrane
0.35	GO:0005764	lysosome
0.34	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.78

EC:2.8.2

GO:0008146

sp|P19238|CD5_BOVIN
T-cell surface glycoprotein CD5
Search

CD5

0.97	T-cell surface glycoprotein CD5

0.72	GO:0006898	receptor-mediated endocytosis
0.64	GO:0031295	T cell costimulation
0.60	GO:0097190	apoptotic signaling pathway
0.36	GO:0008037	cell recognition
0.36	GO:0008283	cell proliferation
0.35	GO:0009966	regulation of signal transduction
0.31	GO:0006468	protein phosphorylation
0.31	GO:0006508	proteolysis
0.31	GO:0005975	carbohydrate metabolic process

0.81	GO:0005044	scavenger receptor activity
0.37	GO:0005515	protein binding
0.35	GO:0004888	transmembrane signaling receptor activity
0.32	GO:0004568	chitinase activity
0.32	GO:0008061	chitin binding
0.32	GO:0030246	carbohydrate binding
0.32	GO:0140096	catalytic activity, acting on a protein
0.32	GO:0017171	serine hydrolase activity
0.31	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.31	GO:0016301	kinase activity

0.60	GO:0009897	external side of plasma membrane
0.37	GO:0044214	spanning component of plasma membrane

0.32

EC:3.2.1.14

GO:0004568

sp|P19427|DERM_BOVIN
Dermatopontin
Search

DPT

0.97	Dermatopontin

0.84	GO:0030199	collagen fibril organization
0.75	GO:0008285	negative regulation of cell proliferation
0.44	GO:0007155	cell adhesion

0.74	GO:0031012	extracellular matrix
0.73	GO:0005615	extracellular space
0.43	GO:1903561	extracellular vesicle

sp|P19483|ATPA_BOVIN
ATP synthase subunit alpha, mitochondrial
Search

ATP5A1

0.45	ATP synthase subunit alpha

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.69	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.52	GO:0001937	negative regulation of endothelial cell proliferation
0.51	GO:0043536	positive regulation of blood vessel endothelial cell migration
0.43	GO:0006629	lipid metabolic process
0.35	GO:0042407	cristae formation
0.34	GO:0006839	mitochondrial transport
0.33	GO:0046907	intracellular transport

0.71	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0043532	angiostatin binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0042288	MHC class I protein binding
0.34	GO:0003723	RNA binding

0.71	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)
0.51	GO:0043209	myelin sheath
0.49	GO:0008180	COP9 signalosome
0.49	GO:0005753	mitochondrial proton-transporting ATP synthase complex
0.41	GO:0005886	plasma membrane
0.36	GO:0031012	extracellular matrix
0.36	GO:0070062	extracellular exosome
0.34	GO:0045121	membrane raft
0.34	GO:0005759	mitochondrial matrix

sp|P19534|CADH2_BOVIN
Cadherin-2 (Fragment)
Search

CDH2

0.92	Cadherin 2, type 1 preproprotein (Predicted)

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.70	GO:0009966	regulation of signal transduction
0.60	GO:0044331	cell-cell adhesion mediated by cadherin
0.58	GO:1902897	regulation of postsynaptic density protein 95 clustering
0.58	GO:0097150	neuronal stem cell population maintenance
0.58	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly
0.57	GO:2000809	positive regulation of synaptic vesicle clustering
0.57	GO:0070445	regulation of oligodendrocyte progenitor proliferation
0.56	GO:0060019	radial glial cell differentiation
0.55	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules

0.70	GO:0005509	calcium ion binding
0.56	GO:0045295	gamma-catenin binding
0.56	GO:0045294	alpha-catenin binding
0.53	GO:0019903	protein phosphatase binding
0.53	GO:0008013	beta-catenin binding
0.51	GO:0019901	protein kinase binding
0.49	GO:0042802	identical protein binding
0.35	GO:0050998	nitric-oxide synthase binding
0.35	GO:0050840	extracellular matrix binding
0.34	GO:0045296	cadherin binding

0.57	GO:0014704	intercalated disc
0.56	GO:0005886	plasma membrane
0.54	GO:0005913	cell-cell adherens junction
0.53	GO:0014069	postsynaptic density
0.53	GO:0030027	lamellipodium
0.52	GO:0098857	membrane microdomain
0.52	GO:0045177	apical part of cell
0.52	GO:0030864	cortical actin cytoskeleton
0.51	GO:0009986	cell surface
0.50	GO:0019898	extrinsic component of membrane

sp|P19535|CADH3_BOVIN
Cadherin-3 (Fragment)
Search

CDH3

0.85	Cadherin 3

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.60	GO:0060901	regulation of hair cycle by canonical Wnt signaling pathway
0.60	GO:1902910	positive regulation of melanosome transport
0.60	GO:0051796	negative regulation of timing of catagen
0.60	GO:0032771	regulation of monophenol monooxygenase activity
0.60	GO:0032912	negative regulation of transforming growth factor beta2 production
0.59	GO:0048023	positive regulation of melanin biosynthetic process
0.58	GO:0010838	positive regulation of keratinocyte proliferation
0.58	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway
0.57	GO:0032770	positive regulation of monooxygenase activity

0.70	GO:0005509	calcium ion binding
0.53	GO:0045295	gamma-catenin binding
0.53	GO:0032794	GTPase activating protein binding
0.53	GO:0030506	ankyrin binding
0.50	GO:0008013	beta-catenin binding
0.49	GO:0045296	cadherin binding
0.47	GO:0042802	identical protein binding
0.36	GO:0045294	alpha-catenin binding
0.36	GO:0019903	protein phosphatase binding
0.35	GO:0019904	protein domain specific binding

0.59	GO:0005913	cell-cell adherens junction
0.55	GO:0005886	plasma membrane
0.50	GO:0030027	lamellipodium
0.49	GO:0030864	cortical actin cytoskeleton
0.49	GO:0043296	apical junction complex
0.49	GO:0098857	membrane microdomain
0.49	GO:0005802	trans-Golgi network
0.49	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0019898	extrinsic component of membrane
0.47	GO:0098562	cytoplasmic side of membrane

sp|P19632|PHOS_BOVIN
Phosducin
Search

PDC

0.73	Phosducin b

0.57	GO:0008616	queuosine biosynthetic process
0.52	GO:0007601	visual perception
0.42	GO:0050896	response to stimulus
0.38	GO:0043086	negative regulation of catalytic activity
0.36	GO:0023052	signaling
0.35	GO:0007154	cell communication
0.34	GO:0050789	regulation of biological process

0.60	GO:0008479	queuine tRNA-ribosyltransferase activity
0.40	GO:0004859	phospholipase inhibitor activity

0.84	GO:0001750	photoreceptor outer segment
0.56	GO:0001917	photoreceptor inner segment
0.48	GO:0005829	cytosol
0.44	GO:0005634	nucleus

0.60

EC:2.4.2.29

GO:0008479

sp|P19660|CTHL2_BOVIN
Cathelicidin-2
Search

0.96	Preprocathelicidin antimicrobial peptide

0.72	GO:0006952	defense response
0.54	GO:0009617	response to bacterium
0.42	GO:0044140	negative regulation of growth of symbiont on or near host surface
0.41	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.41	GO:0044130	negative regulation of growth of symbiont in host
0.40	GO:0031640	killing of cells of other organism
0.40	GO:0051851	modification by host of symbiont morphology or physiology
0.39	GO:0051818	disruption of cells of other organism involved in symbiotic interaction
0.37	GO:0019835	cytolysis
0.36	GO:0009620	response to fungus

0.32

GO:0005509

calcium ion binding

0.66	GO:0005576	extracellular region
0.40	GO:0042581	specific granule
0.34	GO:0042995	cell projection
0.30	GO:0016020	membrane

sp|P19661|CTHL3_BOVIN
Cathelicidin-3
Search

0.97	Preprocathelicidin antimicrobial peptide

0.72	GO:0006952	defense response
0.58	GO:0009617	response to bacterium
0.46	GO:0044140	negative regulation of growth of symbiont on or near host surface
0.45	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.44	GO:0044130	negative regulation of growth of symbiont in host
0.44	GO:0051851	modification by host of symbiont morphology or physiology
0.43	GO:0031640	killing of cells of other organism
0.42	GO:0051818	disruption of cells of other organism involved in symbiotic interaction
0.38	GO:0019835	cytolysis
0.37	GO:0009620	response to fungus

0.33	GO:0005515	protein binding
0.32	GO:0046872	metal ion binding
0.32	GO:0003676	nucleic acid binding

0.66	GO:0005576	extracellular region
0.44	GO:0042581	specific granule
0.35	GO:1904724	tertiary granule lumen
0.34	GO:0034774	secretory granule lumen
0.33	GO:0042995	cell projection
0.30	GO:0016020	membrane

sp|P19687|GCYA1_BOVIN
Guanylate cyclase soluble subunit alpha-1
Search

GUCY1A3

0.97	Guanylate cyclase soluble subunit alpha-1

0.80	GO:0006182	cGMP biosynthetic process
0.63	GO:0052565	response to defense-related host nitric oxide production
0.62	GO:0030828	positive regulation of cGMP biosynthetic process
0.61	GO:0060087	relaxation of vascular smooth muscle
0.61	GO:0035556	intracellular signal transduction
0.57	GO:0008217	regulation of blood pressure
0.42	GO:0090594	inflammatory response to wounding
0.35	GO:0009635	response to herbicide
0.35	GO:0006171	cAMP biosynthetic process
0.34	GO:0014070	response to organic cyclic compound

0.81	GO:0004383	guanylate cyclase activity
0.59	GO:0020037	heme binding
0.51	GO:1901265	nucleoside phosphate binding
0.50	GO:0036094	small molecule binding
0.48	GO:0004016	adenylate cyclase activity
0.36	GO:0047805	cytidylate cyclase activity
0.35	GO:0097367	carbohydrate derivative binding
0.35	GO:0043168	anion binding
0.35	GO:0005515	protein binding
0.33	GO:0004872	receptor activity

0.62	GO:0008074	guanylate cyclase complex, soluble
0.39	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.81	EC:4.6.1.2	GO:0004383
0.36	KEGG:R00574	GO:0047805

sp|P19754|ADCY1_BOVIN
Adenylate cyclase type 1
Search

ADCY1

0.77	Adenylate cyclase type 1

0.74	GO:0006171	cAMP biosynthetic process
0.62	GO:0035556	intracellular signal transduction
0.53	GO:0007616	long-term memory
0.53	GO:0007409	axonogenesis
0.53	GO:0042752	regulation of circadian rhythm
0.48	GO:0006182	cGMP biosynthetic process
0.41	GO:0008038	neuron recognition
0.41	GO:0007605	sensory perception of sound
0.40	GO:0097485	neuron projection guidance
0.40	GO:1904321	response to forskolin

0.74	GO:0004016	adenylate cyclase activity
0.52	GO:1901265	nucleoside phosphate binding
0.50	GO:0036094	small molecule binding
0.48	GO:0004383	guanylate cyclase activity
0.47	GO:0097367	carbohydrate derivative binding
0.47	GO:0008144	drug binding
0.46	GO:0043168	anion binding
0.38	GO:0005516	calmodulin binding
0.34	GO:0046872	metal ion binding

0.53	GO:0005886	plasma membrane
0.50	GO:0008074	guanylate cyclase complex, soluble
0.38	GO:0045121	membrane raft
0.37	GO:0070062	extracellular exosome
0.35	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.74

EC:4.6.1.1

GO:0004016

sp|P19782|PRM2_BOVIN
Protamine-2
Search

PRM2

0.89	Protamine-2

0.83	GO:0007286	spermatid development
0.74	GO:0006323	DNA packaging
0.50	GO:0006997	nucleus organization
0.46	GO:0007275	multicellular organism development

0.55

GO:0003677

DNA binding

0.47	GO:0000786	nucleosome
0.42	GO:0005634	nucleus
0.37	GO:0039615	T=1 icosahedral viral capsid

sp|P19803|GDIR1_BOVIN
Rho GDP-dissociation inhibitor 1
Search

ARHGDIA

0.90	Rho GDP dissociation inhibitor alpha

0.69	GO:0050790	regulation of catalytic activity
0.51	GO:0071526	semaphorin-plexin signaling pathway
0.51	GO:0007266	Rho protein signal transduction
0.47	GO:0032880	regulation of protein localization
0.40	GO:2000249	regulation of actin cytoskeleton reorganization
0.39	GO:0030336	negative regulation of cell migration
0.39	GO:0071461	cellular response to redox state
0.39	GO:0035023	regulation of Rho protein signal transduction
0.38	GO:0044093	positive regulation of molecular function
0.38	GO:0071260	cellular response to mechanical stimulus

0.85	GO:0005094	Rho GDP-dissociation inhibitor activity
0.38	GO:0005096	GTPase activator activity
0.38	GO:0017048	Rho GTPase binding
0.38	GO:0051879	Hsp90 protein binding
0.38	GO:0005504	fatty acid binding
0.37	GO:0019901	protein kinase binding
0.36	GO:0003723	RNA binding
0.35	GO:0003924	GTPase activity

0.51	GO:0001772	immunological synapse
0.49	GO:0005737	cytoplasm
0.42	GO:0005634	nucleus
0.37	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.33	GO:0005856	cytoskeleton

sp|P19858|LDHA_BOVIN
L-lactate dehydrogenase A chain
Search

LDHA

0.54	L-lactate dehydrogenase A chain

0.60	GO:0005975	carbohydrate metabolic process
0.57	GO:0019752	carboxylic acid metabolic process
0.52	GO:0055114	oxidation-reduction process
0.38	GO:0051591	response to cAMP
0.38	GO:0043627	response to estrogen
0.37	GO:0009749	response to glucose
0.37	GO:0042542	response to hydrogen peroxide
0.37	GO:0048569	post-embryonic animal organ development
0.37	GO:0001666	response to hypoxia
0.37	GO:0007584	response to nutrient

0.81	GO:0004459	L-lactate dehydrogenase activity
0.42	GO:0045296	cadherin binding
0.37	GO:0019900	kinase binding
0.36	GO:0042802	identical protein binding
0.35	GO:0051287	NAD binding

0.48	GO:0005737	cytoplasm
0.37	GO:0035686	sperm fibrous sheath
0.36	GO:0070062	extracellular exosome
0.36	GO:0000439	core TFIIH complex
0.30	GO:0016020	membrane

0.81

EC:1.1.1.27

GO:0004459

sp|P19879|MIME_BOVIN
Mimecan
Search

OGN

0.97	Osteoglycin OG

0.60	GO:0007409	axonogenesis
0.48	GO:0010469	regulation of receptor activity
0.43	GO:0048662	negative regulation of smooth muscle cell proliferation
0.41	GO:0042340	keratan sulfate catabolic process
0.41	GO:0018146	keratan sulfate biosynthetic process
0.35	GO:0106074	aminoacyl-tRNA metabolism involved in translational fidelity
0.34	GO:0006418	tRNA aminoacylation for protein translation

0.49	GO:0008083	growth factor activity
0.35	GO:0002161	aminoacyl-tRNA editing activity
0.34	GO:0000049	tRNA binding
0.34	GO:0016875	ligase activity, forming carbon-oxygen bonds
0.33	GO:0046872	metal ion binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.73	GO:0031012	extracellular matrix
0.72	GO:0005615	extracellular space
0.41	GO:1903561	extracellular vesicle
0.40	GO:0043202	lysosomal lumen
0.40	GO:0005796	Golgi lumen
0.37	GO:0005783	endoplasmic reticulum
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:6.1

GO:0016875

sp|P20000|ALDH2_BOVIN
Aldehyde dehydrogenase, mitochondrial
Search

ALDH2

0.40	Mitochondrial aldehyde dehydrogenase 2

0.52	GO:0055114	oxidation-reduction process
0.46	GO:0006068	ethanol catabolic process
0.39	GO:2001038	regulation of cellular response to drug
0.36	GO:0033574	response to testosterone
0.36	GO:0055093	response to hyperoxia
0.36	GO:0032570	response to progesterone
0.36	GO:0035094	response to nicotine
0.36	GO:0071398	cellular response to fatty acid
0.36	GO:0032355	response to estradiol
0.36	GO:0001889	liver development

0.69	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.39	GO:0051287	NAD binding
0.35	GO:0005515	protein binding
0.33	GO:0009055	electron transfer activity
0.33	GO:0043168	anion binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding

0.45	GO:0005739	mitochondrion
0.40	GO:0031974	membrane-enclosed lumen
0.38	GO:0044446	intracellular organelle part
0.37	GO:0070062	extracellular exosome

0.69

GO:0016620

sp|P20004|ACON_BOVIN
Aconitate hydratase, mitochondrial
Search

ACO2

0.70	Aconitate hydratase, mitochondrial

0.68	GO:0006099	tricarboxylic acid cycle
0.39	GO:0035900	response to isolation stress
0.38	GO:0001889	liver development
0.37	GO:0006102	isocitrate metabolic process

0.76	GO:0003994	aconitate hydratase activity
0.65	GO:0051539	4 iron, 4 sulfur cluster binding
0.52	GO:0046872	metal ion binding
0.38	GO:0051538	3 iron, 4 sulfur cluster binding
0.33	GO:0005515	protein binding

0.59	GO:0005739	mitochondrion
0.51	GO:0043209	myelin sheath
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0044425	membrane part

0.76

EC:4.2.1.3

GO:0003994

sp|P20072|ANXA7_BOVIN
Annexin A7
Search

ANXA7

0.64

Annexin

0.55	GO:0009992	cellular water homeostasis
0.54	GO:0035176	social behavior
0.51	GO:0009651	response to salt stress
0.51	GO:0030855	epithelial cell differentiation
0.51	GO:0007599	hemostasis
0.50	GO:0006874	cellular calcium ion homeostasis
0.50	GO:0006914	autophagy
0.50	GO:0008283	cell proliferation
0.46	GO:0010629	negative regulation of gene expression
0.46	GO:0008360	regulation of cell shape

0.81	GO:0005544	calcium-dependent phospholipid binding
0.70	GO:0005509	calcium ion binding
0.55	GO:0048306	calcium-dependent protein binding
0.53	GO:0005178	integrin binding
0.37	GO:0008429	phosphatidylethanolamine binding
0.37	GO:0044548	S100 protein binding
0.35	GO:0003723	RNA binding
0.35	GO:0023026	MHC class II protein complex binding
0.35	GO:0042802	identical protein binding

0.57	GO:0042584	chromaffin granule membrane
0.49	GO:0005635	nuclear envelope
0.48	GO:0005789	endoplasmic reticulum membrane
0.46	GO:0005829	cytosol
0.41	GO:0005886	plasma membrane
0.39	GO:0070062	extracellular exosome
0.36	GO:0005766	primary lysosome
0.36	GO:0042581	specific granule
0.36	GO:0030496	midbody
0.36	GO:0045335	phagocytic vesicle

sp|P20237|GBRA4_BOVIN
Gamma-aminobutyric acid receptor subunit alpha-4
Search

GABRA4

0.97	LOW QUALITY PROTEIN: gamma-aminobutyric acid receptor subunit alpha-4

0.82	GO:0007214	gamma-aminobutyric acid signaling pathway
0.73	GO:0006821	chloride transport
0.60	GO:0034220	ion transmembrane transport
0.60	GO:2001023	regulation of response to drug
0.57	GO:0007417	central nervous system development

0.84	GO:0004890	GABA-A receptor activity
0.76	GO:0005230	extracellular ligand-gated ion channel activity
0.40	GO:0005254	chloride channel activity
0.37	GO:0008503	benzodiazepine receptor activity

0.55	GO:0005886	plasma membrane
0.52	GO:1902711	GABA-A receptor complex
0.41	GO:0034707	chloride channel complex
0.40	GO:0098794	postsynapse
0.39	GO:0030054	cell junction

sp|P20274|LMIP_BOVIN
Lens fiber membrane intrinsic protein
Search

0.97	Lens intrinsic membrane protein 2

0.52	GO:0002088	lens development in camera-type eye
0.36	GO:0007043	cell-cell junction assembly

0.84

GO:0005212

structural constituent of eye lens

0.38	GO:0031982	vesicle
0.37	GO:0030054	cell junction
0.35	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|P20288|DRD2_BOVIN
D(2) dopamine receptor
Search

DRD2

0.95	Dopamine receptor 2 protein transcript variant 1

0.86	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway
0.64	GO:0051967	negative regulation of synaptic transmission, glutamatergic
0.63	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway
0.63	GO:0048148	behavioral response to cocaine
0.62	GO:0014059	regulation of dopamine secretion
0.62	GO:0048149	behavioral response to ethanol
0.62	GO:0051944	positive regulation of catecholamine uptake involved in synaptic transmission
0.61	GO:1900166	regulation of glial cell-derived neurotrophic factor secretion
0.61	GO:0060160	negative regulation of dopamine receptor signaling pathway
0.61	GO:0035815	positive regulation of renal sodium excretion

0.85	GO:0004952	dopamine neurotransmitter receptor activity
0.63	GO:0035240	dopamine binding
0.52	GO:0042802	identical protein binding
0.49	GO:0004935	adrenergic receptor activity
0.41	GO:0035255	ionotropic glutamate receptor binding
0.38	GO:0046982	protein heterodimerization activity
0.35	GO:0015459	potassium channel regulator activity

0.67	GO:0005887	integral component of plasma membrane
0.57	GO:0060170	ciliary membrane
0.56	GO:0097730	non-motile cilium
0.55	GO:0030425	dendrite
0.55	GO:0030424	axon
0.50	GO:0030672	synaptic vesicle membrane
0.40	GO:0043204	perikaryon
0.40	GO:0016328	lateral plasma membrane
0.40	GO:0044309	neuron spine
0.40	GO:0043679	axon terminus

sp|P20414|TIMP1_BOVIN
Metalloproteinase inhibitor 1
Search

TIMP1

0.91	Tissue inhibitor of metalloproteinase 1

0.76	GO:0010951	negative regulation of endopeptidase activity
0.70	GO:0051045	negative regulation of membrane protein ectodomain proteolysis
0.70	GO:2001044	regulation of integrin-mediated signaling pathway
0.66	GO:1905049	negative regulation of metallopeptidase activity
0.66	GO:1901164	negative regulation of trophoblast cell migration
0.62	GO:0008284	positive regulation of cell proliferation
0.60	GO:0010469	regulation of receptor activity
0.51	GO:0034097	response to cytokine
0.49	GO:0009725	response to hormone
0.43	GO:0051216	cartilage development

0.85	GO:0008191	metalloendopeptidase inhibitor activity
0.63	GO:0005125	cytokine activity
0.54	GO:0002020	protease binding
0.51	GO:0008083	growth factor activity
0.49	GO:0008270	zinc ion binding
0.34	GO:0008237	metallopeptidase activity

0.66	GO:0005576	extracellular region
0.38	GO:0031093	platelet alpha granule lumen
0.37	GO:0005788	endoplasmic reticulum lumen
0.36	GO:0005581	collagen trimer

sp|P20427|CSK22_BOVIN
Casein kinase II subunit alpha'
Search

CSNK2A2

0.80	Casein kinase II subunit alpha'

0.63	GO:0006468	protein phosphorylation
0.56	GO:1903146	regulation of autophagy of mitochondrion
0.56	GO:1903955	positive regulation of protein targeting to mitochondrion
0.53	GO:1905818	regulation of chromosome separation
0.40	GO:0097421	liver regeneration
0.39	GO:0021987	cerebral cortex development
0.38	GO:0007283	spermatogenesis
0.38	GO:0016055	Wnt signaling pathway
0.37	GO:0006915	apoptotic process
0.35	GO:0007049	cell cycle

0.68	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0047485	protein N-terminus binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.54	GO:0031519	PcG protein complex
0.39	GO:0001669	acrosomal vesicle
0.37	GO:0000785	chromatin
0.35	GO:0005956	protein kinase CK2 complex
0.34	GO:0005886	plasma membrane
0.34	GO:0005654	nucleoplasm
0.33	GO:0005829	cytosol

0.68

GO:0004674

sp|P20456|IMPA1_BOVIN
Inositol monophosphatase 1
Search

IMPA1

0.41	Inositol monophosphatase 1

0.81	GO:0006021	inositol biosynthetic process
0.79	GO:0046855	inositol phosphate dephosphorylation
0.75	GO:0046854	phosphatidylinositol phosphorylation
0.50	GO:0006661	phosphatidylinositol biosynthetic process
0.44	GO:0007165	signal transduction
0.35	GO:0010226	response to lithium ion

0.79	GO:0008934	inositol monophosphate 1-phosphatase activity
0.79	GO:0052832	inositol monophosphate 3-phosphatase activity
0.79	GO:0052833	inositol monophosphate 4-phosphatase activity
0.58	GO:0031403	lithium ion binding
0.49	GO:0042803	protein homodimerization activity
0.49	GO:0030145	manganese ion binding
0.45	GO:0000287	magnesium ion binding

0.38	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.34	GO:0043025	neuronal cell body
0.34	GO:0030424	axon
0.30	GO:0016020	membrane

0.79

EC:3.1.3.25

GO:0008934

sp|P20488|SYPH_BOVIN
Synaptophysin
Search

SYP

0.94	Synaptophysin a

0.74	GO:0048168	regulation of neuronal synaptic plasticity
0.52	GO:0048488	synaptic vesicle endocytosis
0.47	GO:0071310	cellular response to organic substance
0.39	GO:2000474	regulation of opioid receptor signaling pathway
0.38	GO:0045920	negative regulation of exocytosis
0.36	GO:0048499	synaptic vesicle membrane organization
0.36	GO:0016188	synaptic vesicle maturation
0.35	GO:0043029	T cell homeostasis
0.35	GO:0050856	regulation of T cell receptor signaling pathway
0.35	GO:0007601	visual perception

0.53	GO:0042169	SH2 domain binding
0.51	GO:0015485	cholesterol binding
0.47	GO:0042802	identical protein binding
0.36	GO:0051020	GTPase binding
0.36	GO:0008331	high voltage-gated calcium channel activity
0.35	GO:0043621	protein self-association
0.33	GO:0008270	zinc ion binding
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0032561	guanyl ribonucleotide binding

0.82	GO:0008021	synaptic vesicle
0.57	GO:0099501	exocytic vesicle membrane
0.53	GO:0060076	excitatory synapse
0.52	GO:0042734	presynaptic membrane
0.52	GO:0043195	terminal bouton
0.51	GO:0031594	neuromuscular junction
0.51	GO:0048786	presynaptic active zone
0.47	GO:0031301	integral component of organelle membrane
0.39	GO:0030054	cell junction
0.39	GO:0042584	chromaffin granule membrane

sp|P20616|SCG2_BOVIN
Secretogranin-2
Search

SCG2

0.97	Secretogranin II

0.61	GO:0048245	eosinophil chemotaxis
0.61	GO:0050930	induction of positive chemotaxis
0.60	GO:2000352	negative regulation of endothelial cell apoptotic process
0.59	GO:0050918	positive chemotaxis
0.59	GO:0001938	positive regulation of endothelial cell proliferation
0.59	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway
0.57	GO:0001525	angiogenesis
0.55	GO:0000165	MAPK cascade
0.53	GO:0010469	regulation of receptor activity
0.37	GO:0001937	negative regulation of endothelial cell proliferation

0.60	GO:0042056	chemoattractant activity
0.56	GO:0005125	cytokine activity

0.81	GO:0030141	secretory granule
0.52	GO:0005615	extracellular space
0.52	GO:0097458	neuron part
0.36	GO:0005788	endoplasmic reticulum lumen
0.35	GO:0030117	membrane coat
0.34	GO:0030133	transport vesicle
0.30	GO:0016021	integral component of membrane

sp|P20811|ICAL_BOVIN
Calpastatin
Search

CAST

0.55	Calpastatin type III

0.85	GO:2000675	negative regulation of type B pancreatic cell apoptotic process
0.83	GO:0097340	inhibition of cysteine-type endopeptidase activity

0.85	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity
0.75	GO:0045296	cadherin binding

0.66	GO:0005783	endoplasmic reticulum
0.64	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|P20821|GCSH_BOVIN
Glycine cleavage system H protein, mitochondrial
Search

GCSH

0.46	Glycine cleavage system H protein, mitochondrial

0.77	GO:0019464	glycine decarboxylation via glycine cleavage system
0.42	GO:0009249	protein lipoylation
0.34	GO:0032259	methylation
0.33	GO:0098869	cellular oxidant detoxification
0.32	GO:0055114	oxidation-reduction process
0.32	GO:0034641	cellular nitrogen compound metabolic process

0.36	GO:0004047	aminomethyltransferase activity
0.35	GO:0005515	protein binding
0.34	GO:0030246	carbohydrate binding
0.34	GO:0005509	calcium ion binding
0.33	GO:0004096	catalase activity
0.33	GO:0020037	heme binding

0.78	GO:0005960	glycine cleavage complex
0.59	GO:0005739	mitochondrion
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.36

EC:2.1.2.10

GO:0004047

sp|P20959|IBP3_BOVIN
Insulin-like growth factor-binding protein 3
Search

IGFBP3

0.94	Insulin like growth factor binding protein 3

0.70	GO:0001558	regulation of cell growth
0.59	GO:0014912	negative regulation of smooth muscle cell migration
0.59	GO:0044342	type B pancreatic cell proliferation
0.58	GO:0045663	positive regulation of myoblast differentiation
0.58	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway
0.58	GO:0048662	negative regulation of smooth muscle cell proliferation
0.56	GO:0001649	osteoblast differentiation
0.55	GO:0010906	regulation of glucose metabolic process
0.54	GO:0043666	regulation of phosphoprotein phosphatase activity
0.54	GO:0043065	positive regulation of apoptotic process

0.83	GO:0005520	insulin-like growth factor binding
0.61	GO:0008160	protein tyrosine phosphatase activator activity
0.58	GO:0001968	fibronectin binding
0.33	GO:0046872	metal ion binding

0.65	GO:0005576	extracellular region
0.60	GO:0036454	growth factor complex
0.46	GO:0005634	nucleus
0.36	GO:0031982	vesicle
0.36	GO:0005788	endoplasmic reticulum lumen
0.36	GO:0000792	heterochromatin

sp|P21146|ARBK1_BOVIN
Beta-adrenergic receptor kinase 1
Search

0.69	G protein-coupled receptor kinase

0.63	GO:0006468	protein phosphorylation
0.61	GO:0007165	signal transduction
0.59	GO:0031623	receptor internalization
0.57	GO:0003108	negative regulation of the force of heart contraction by chemical signal
0.55	GO:0045988	negative regulation of striated muscle contraction
0.55	GO:0002029	desensitization of G-protein coupled receptor protein signaling pathway
0.53	GO:0060048	cardiac muscle contraction
0.52	GO:0007507	heart development
0.52	GO:0018210	peptidyl-threonine modification
0.51	GO:0018209	peptidyl-serine modification

0.85	GO:0004703	G-protein coupled receptor kinase activity
0.57	GO:0031755	Edg-2 lysophosphatidic acid receptor binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0047696	beta-adrenergic receptor kinase activity
0.38	GO:0031694	alpha-2A adrenergic receptor binding
0.34	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.34	GO:0004725	protein tyrosine phosphatase activity

0.38	GO:0005737	cytoplasm
0.36	GO:0120025	plasma membrane bounded cell projection
0.36	GO:0005886	plasma membrane
0.34	GO:0045121	membrane raft
0.34	GO:0045177	apical part of cell
0.34	GO:0036477	somatodendritic compartment
0.34	GO:0098794	postsynapse
0.34	GO:0044463	cell projection part
0.33	GO:0043226	organelle

0.85

GO:0004703

sp|P21214|TGFB2_BOVIN
Transforming growth factor beta-2
Search

TGFB2

0.85	Transforming growth factor beta-2

0.80	GO:0016049	cell growth
0.74	GO:0010469	regulation of receptor activity
0.67	GO:0051795	positive regulation of timing of catagen
0.67	GO:0045726	positive regulation of integrin biosynthetic process
0.67	GO:0010693	negative regulation of alkaline phosphatase activity
0.66	GO:0051891	positive regulation of cardioblast differentiation
0.66	GO:0010936	negative regulation of macrophage cytokine production
0.66	GO:0032909	regulation of transforming growth factor beta2 production
0.65	GO:0060389	pathway-restricted SMAD protein phosphorylation
0.65	GO:0060038	cardiac muscle cell proliferation

0.85	GO:0005160	transforming growth factor beta receptor binding
0.76	GO:0008083	growth factor activity
0.63	GO:0001540	amyloid-beta binding
0.56	GO:0042803	protein homodimerization activity
0.44	GO:0005125	cytokine activity
0.35	GO:0004702	signal transducer, downstream of receptor, with serine/threonine kinase activity
0.35	GO:0046982	protein heterodimerization activity

0.72	GO:0005615	extracellular space
0.56	GO:0031012	extracellular matrix
0.41	GO:0043025	neuronal cell body
0.41	GO:0030424	axon
0.36	GO:0031093	platelet alpha granule lumen
0.35	GO:0005768	endosome

0.35

GO:0004702

sp|P21282|VATC1_BOVIN
V-type proton ATPase subunit C 1
Search

ATP6V1C1

0.67	V-type proton ATPase subunit C

0.75	GO:0015991	ATP hydrolysis coupled proton transport
0.35	GO:0090383	phagosome acidification
0.35	GO:0033572	transferrin transport
0.35	GO:0008286	insulin receptor signaling pathway
0.35	GO:0016241	regulation of macroautophagy

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.55	GO:0036442	proton-exporting ATPase activity
0.53	GO:0015662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
0.44	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
0.33	GO:0005515	protein binding

0.80	GO:0033180	proton-transporting V-type ATPase, V1 domain
0.48	GO:0005765	lysosomal membrane
0.48	GO:0016471	vacuolar proton-transporting V-type ATPase complex
0.42	GO:0005886	plasma membrane
0.38	GO:0045177	apical part of cell
0.37	GO:0031410	cytoplasmic vesicle
0.36	GO:0070062	extracellular exosome
0.33	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

sp|P21327|INPP_BOVIN
Inositol polyphosphate 1-phosphatase
Search

INPP1

0.95	Inositol polyphosphate 1-phosphatase

0.75	GO:0046854	phosphatidylinositol phosphorylation
0.40	GO:0043647	inositol phosphate metabolic process
0.40	GO:0016311	dephosphorylation
0.39	GO:0007268	chemical synaptic transmission
0.39	GO:0046174	polyol catabolic process
0.38	GO:0046434	organophosphate catabolic process
0.37	GO:0044262	cellular carbohydrate metabolic process
0.34	GO:0030041	actin filament polymerization
0.34	GO:0034314	Arp2/3 complex-mediated actin nucleation
0.33	GO:0007165	signal transduction

0.46	GO:0004441	inositol-1,4-bisphosphate 1-phosphatase activity
0.37	GO:0052829	inositol-1,3,4-trisphosphate 1-phosphatase activity
0.35	GO:0005515	protein binding
0.34	GO:0046872	metal ion binding
0.33	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.33	GO:0052689	carboxylic ester hydrolase activity
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.34	GO:0005829	cytosol
0.34	GO:0005885	Arp2/3 protein complex
0.32	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.46	EC:3.1.3.57	GO:0004441
0.33	KEGG:R00630	GO:0052689

sp|P21398|AOFA_BOVIN
Amine oxidase [flavin-containing] A
Search

MAOA

0.48	Amine oxidase [flavin-containing] A

0.55	GO:0042420	dopamine catabolic process
0.52	GO:0055114	oxidation-reduction process
0.40	GO:0042135	neurotransmitter catabolic process
0.36	GO:0042443	phenylethylamine metabolic process
0.35	GO:0042428	serotonin metabolic process
0.34	GO:0019221	cytokine-mediated signaling pathway
0.34	GO:0042402	cellular biogenic amine catabolic process

0.54	GO:0016491	oxidoreductase activity
0.35	GO:0051378	serotonin binding
0.33	GO:0050660	flavin adenine dinucleotide binding
0.33	GO:0005515	protein binding

0.47	GO:0005739	mitochondrion
0.44	GO:0031967	organelle envelope
0.44	GO:0031090	organelle membrane
0.42	GO:0098805	whole membrane
0.40	GO:0019867	outer membrane
0.30	GO:0016021	integral component of membrane

0.54

EC:1

GO:0016491

sp|P21450|EDNRA_BOVIN
Endothelin-1 receptor
Search

EDNRA

0.97	Endothelin receptor type A

0.86	GO:0086100	endothelin receptor signaling pathway
0.85	GO:0048484	enteric nervous system development
0.85	GO:0042310	vasoconstriction
0.83	GO:0008217	regulation of blood pressure
0.61	GO:0014820	tonic smooth muscle contraction
0.59	GO:0001569	branching involved in blood vessel morphogenesis
0.58	GO:0007585	respiratory gaseous exchange
0.57	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.57	GO:0014032	neural crest cell development
0.56	GO:0015758	glucose transport

0.86	GO:0004962	endothelin receptor activity
0.35	GO:0004435	phosphatidylinositol phospholipase C activity
0.34	GO:0004713	protein tyrosine kinase activity
0.34	GO:0005515	protein binding
0.33	GO:0003924	GTPase activity
0.33	GO:0005525	GTP binding
0.32	GO:0003735	structural constituent of ribosome

0.36	GO:0005886	plasma membrane
0.35	GO:0098857	membrane microdomain
0.34	GO:0031965	nuclear membrane
0.32	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.35	EC:3.1.4.11	GO:0004435
0.35	KEGG:R03435	GO:0004435

sp|P21457|RECO_BOVIN
Recoverin
Search

RCVRN

0.97	Recoverin a

0.57	GO:0009416	response to light stimulus
0.53	GO:0051924	regulation of calcium ion transport
0.52	GO:0007601	visual perception
0.51	GO:0009582	detection of abiotic stimulus
0.51	GO:0009581	detection of external stimulus
0.44	GO:0007165	signal transduction
0.36	GO:0010562	positive regulation of phosphorus metabolic process
0.35	GO:0043085	positive regulation of catalytic activity
0.35	GO:0031282	regulation of guanylate cyclase activity
0.35	GO:1904063	negative regulation of cation transmembrane transport

0.70	GO:0005509	calcium ion binding
0.35	GO:0008047	enzyme activator activity
0.35	GO:0010853	cyclase activator activity
0.35	GO:0030249	guanylate cyclase regulator activity
0.34	GO:0019207	kinase regulator activity
0.34	GO:0004354	glutamate dehydrogenase (NADP+) activity
0.33	GO:0005515	protein binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.40	GO:0030425	dendrite
0.34	GO:0000139	Golgi membrane
0.34	GO:0005829	cytosol
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.34

EC:1.4.1.4

GO:0004354

sp|P21671|PLCD4_BOVIN
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4
Search

PLCD4

0.58	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4

0.85	GO:0007340	acrosome reaction
0.74	GO:0046488	phosphatidylinositol metabolic process
0.67	GO:0016042	lipid catabolic process
0.63	GO:0035556	intracellular signal transduction

0.80	GO:0004629	phospholipase C activity
0.65	GO:0005509	calcium ion binding
0.60	GO:0004871	signal transducer activity

0.66	GO:0005783	endoplasmic reticulum
0.58	GO:0005634	nucleus
0.50	GO:0005829	cytosol
0.47	GO:0031967	organelle envelope
0.47	GO:0031090	organelle membrane
0.44	GO:0005886	plasma membrane

sp|P21752|TYB10_BOVIN
Thymosin beta-10
Search

0.94	thymosin beta-b

0.75	GO:0007015	actin filament organization
0.47	GO:1905271	regulation of proton-transporting ATP synthase activity, rotational mechanism
0.46	GO:0042989	sequestering of actin monomers
0.45	GO:0007253	cytoplasmic sequestering of NF-kappaB
0.45	GO:2000483	negative regulation of interleukin-8 secretion
0.45	GO:2001171	positive regulation of ATP biosynthetic process
0.45	GO:1901223	negative regulation of NIK/NF-kappaB signaling
0.45	GO:2001028	positive regulation of endothelial cell chemotaxis
0.45	GO:1903026	negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding
0.44	GO:0043536	positive regulation of blood vessel endothelial cell migration

0.85	GO:0003785	actin monomer binding
0.41	GO:0019899	enzyme binding
0.35	GO:0003727	single-stranded RNA binding
0.34	GO:0004888	transmembrane signaling receptor activity

0.43	GO:0005856	cytoskeleton
0.41	GO:0005829	cytosol
0.40	GO:0005576	extracellular region
0.39	GO:0005634	nucleus
0.35	GO:0031093	platelet alpha granule lumen
0.30	GO:0044425	membrane part

sp|P21758|MSRE_BOVIN
Macrophage scavenger receptor types I and II
Search

MSR1

0.95	Macrophage scavenger receptor types I and II

0.71	GO:0006898	receptor-mediated endocytosis
0.61	GO:0097242	amyloid-beta clearance
0.61	GO:0010886	positive regulation of cholesterol storage
0.61	GO:0010744	positive regulation of macrophage derived foam cell differentiation
0.60	GO:0034381	plasma lipoprotein particle clearance
0.58	GO:0006911	phagocytosis, engulfment
0.57	GO:0030301	cholesterol transport
0.54	GO:0042953	lipoprotein transport
0.52	GO:0034755	iron ion transmembrane transport
0.51	GO:0006879	cellular iron ion homeostasis

0.80	GO:0005044	scavenger receptor activity
0.60	GO:0030169	low-density lipoprotein particle binding
0.60	GO:0070287	ferritin receptor activity
0.58	GO:0001540	amyloid-beta binding
0.38	GO:0051879	Hsp90 protein binding
0.38	GO:0030544	Hsp70 protein binding
0.36	GO:0042802	identical protein binding
0.36	GO:0019899	enzyme binding

0.47	GO:0005887	integral component of plasma membrane
0.45	GO:0009986	cell surface
0.44	GO:0034362	low-density lipoprotein particle
0.42	GO:0005581	collagen trimer
0.37	GO:0031410	cytoplasmic vesicle
0.36	GO:0012506	vesicle membrane
0.35	GO:0098805	whole membrane
0.35	GO:0098588	bounding membrane of organelle
0.34	GO:0005829	cytosol
0.34	GO:0044446	intracellular organelle part

sp|P21782|PTN_BOVIN
Pleiotrophin
Search

PTN

0.97	Pleiotrophin

0.76	GO:0010469	regulation of receptor activity
0.55	GO:0030282	bone mineralization
0.54	GO:0007611	learning or memory
0.53	GO:0008284	positive regulation of cell proliferation
0.44	GO:0007399	nervous system development
0.42	GO:0051781	positive regulation of cell division
0.42	GO:1904391	response to ciliary neurotrophic factor
0.41	GO:1904373	response to kainic acid
0.41	GO:0060322	head development
0.41	GO:1904395	positive regulation of skeletal muscle acetylcholine-gated channel clustering

0.78	GO:0008083	growth factor activity
0.59	GO:0035374	chondroitin sulfate binding
0.55	GO:0008201	heparin binding
0.51	GO:0019901	protein kinase binding
0.41	GO:1904399	heparan sulfate binding
0.41	GO:0035373	chondroitin sulfate proteoglycan binding
0.41	GO:0038085	vascular endothelial growth factor binding
0.35	GO:0004864	protein phosphatase inhibitor activity
0.32	GO:0016301	kinase activity

0.50	GO:0005615	extracellular space
0.48	GO:0005783	endoplasmic reticulum
0.43	GO:0043234	protein complex
0.39	GO:0031594	neuromuscular junction
0.39	GO:0005604	basement membrane
0.38	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0009986	cell surface
0.30	GO:0016020	membrane

sp|P21793|PGS2_BOVIN
Decorin
Search

DCN

0.97

Decorin

0.61	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway
0.60	GO:0051901	positive regulation of mitochondrial depolarization
0.60	GO:0050654	chondroitin sulfate proteoglycan metabolic process
0.59	GO:0090141	positive regulation of mitochondrial fission
0.58	GO:0010596	negative regulation of endothelial cell migration
0.58	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling
0.57	GO:0016239	positive regulation of macroautophagy
0.57	GO:0016525	negative regulation of angiogenesis
0.56	GO:0018149	peptide cross-linking
0.56	GO:1903510	mucopolysaccharide metabolic process

0.83	GO:0005518	collagen binding
0.56	GO:0050840	extracellular matrix binding
0.52	GO:0005539	glycosaminoglycan binding
0.48	GO:0004860	protein kinase inhibitor activity
0.40	GO:0047485	protein N-terminus binding
0.36	GO:0098633	collagen fibril binding
0.34	GO:0042803	protein homodimerization activity
0.34	GO:0003723	RNA binding

0.75	GO:0005578	proteinaceous extracellular matrix
0.52	GO:0005615	extracellular space
0.42	GO:0098647	collagen beaded filament
0.39	GO:0005581	collagen trimer
0.36	GO:0005737	cytoplasm
0.33	GO:0012505	endomembrane system
0.33	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part
0.33	GO:0043231	intracellular membrane-bounded organelle

sp|P21809|PGS1_BOVIN
Biglycan
Search

BGN

0.96

Biglycan

0.60	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan
0.49	GO:0046426	negative regulation of JAK-STAT cascade
0.47	GO:0006469	negative regulation of protein kinase activity
0.47	GO:0019221	cytokine-mediated signaling pathway
0.41	GO:0001974	blood vessel remodeling
0.37	GO:0030207	chondroitin sulfate catabolic process
0.37	GO:0030208	dermatan sulfate biosynthetic process
0.36	GO:0030206	chondroitin sulfate biosynthetic process
0.35	GO:0030198	extracellular matrix organization

0.57	GO:0050840	extracellular matrix binding
0.53	GO:0005539	glycosaminoglycan binding
0.48	GO:0004860	protein kinase inhibitor activity
0.35	GO:0005201	extracellular matrix structural constituent
0.31	GO:0005515	protein binding

0.75	GO:0005578	proteinaceous extracellular matrix
0.57	GO:0042383	sarcolemma
0.54	GO:0030133	transport vesicle
0.53	GO:0009986	cell surface
0.51	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.36	GO:0043202	lysosomal lumen
0.36	GO:0005796	Golgi lumen

sp|P21839|ODBB_BOVIN
2-oxoisovalerate dehydrogenase subunit beta, mitochondrial
Search

BCKDHB

0.92	Branched chain keto acid dehydrogenase E1 beta polypeptide

0.63	GO:0009083	branched-chain amino acid catabolic process
0.44	GO:0055114	oxidation-reduction process

0.62	GO:0003826	alpha-ketoacid dehydrogenase activity
0.36	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity

0.67

GO:0005947

mitochondrial alpha-ketoglutarate dehydrogenase complex

0.36

EC:1.2.4.1

GO:0004739

sp|P21856|GDIA_BOVIN
Rab GDP dissociation inhibitor alpha
Search

GDI1

0.68	Rab GDP dissociation inhibitor alpha

0.77	GO:0007264	small GTPase mediated signal transduction
0.76	GO:0043547	positive regulation of GTPase activity
0.65	GO:0015031	protein transport
0.55	GO:0090315	negative regulation of protein targeting to membrane
0.43	GO:0050771	negative regulation of axonogenesis
0.39	GO:0045773	positive regulation of axon extension
0.39	GO:0051592	response to calcium ion
0.34	GO:0016192	vesicle-mediated transport
0.34	GO:0051056	regulation of small GTPase mediated signal transduction

0.85	GO:0005093	Rab GDP-dissociation inhibitor activity
0.76	GO:0005096	GTPase activator activity
0.39	GO:0031267	small GTPase binding
0.33	GO:0003723	RNA binding
0.32	GO:0016740	transferase activity

0.53	GO:0043209	myelin sheath
0.50	GO:0030496	midbody
0.49	GO:0005737	cytoplasm
0.42	GO:0012505	endomembrane system
0.38	GO:0043025	neuronal cell body
0.38	GO:0043231	intracellular membrane-bounded organelle
0.38	GO:0030424	axon
0.35	GO:0043234	protein complex
0.34	GO:0005925	focal adhesion
0.34	GO:0070062	extracellular exosome

0.32

GO:0016740

sp|P22027|ATP5S_BOVIN
ATP synthase subunit s, mitochondrial
Search

ATP5S

0.96	Mitochondrial ATP synthase subunit s

0.50	GO:0006754	ATP biosynthetic process
0.46	GO:0015992	proton transport
0.42	GO:0042407	cristae formation
0.40	GO:0006839	mitochondrial transport
0.38	GO:0046907	intracellular transport
0.37	GO:0098662	inorganic cation transmembrane transport

0.42	GO:0046872	metal ion binding
0.37	GO:0015078	hydrogen ion transmembrane transporter activity

0.60	GO:0005739	mitochondrion
0.51	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)
0.46	GO:0019866	organelle inner membrane

sp|P22226|CTHL1_BOVIN
Cathelicidin-1
Search

0.95	Preprocathelicidin antimicrobial peptide

0.72	GO:0006952	defense response
0.55	GO:0009617	response to bacterium
0.42	GO:0044140	negative regulation of growth of symbiont on or near host surface
0.42	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.41	GO:0044130	negative regulation of growth of symbiont in host
0.41	GO:0031640	killing of cells of other organism
0.41	GO:0051851	modification by host of symbiont morphology or physiology
0.39	GO:0051818	disruption of cells of other organism involved in symbiotic interaction
0.39	GO:0019835	cytolysis
0.36	GO:0009620	response to fungus

0.66	GO:0005576	extracellular region
0.41	GO:0042581	specific granule
0.34	GO:0042995	cell projection
0.30	GO:0016020	membrane

sp|P22292|M2OM_BOVIN
Mitochondrial 2-oxoglutarate/malate carrier protein
Search

SLC25A11

0.59	RAN guanine nucleotide release factor

0.57	GO:0006839	mitochondrial transport
0.51	GO:0015742	alpha-ketoglutarate transport
0.36	GO:0030488	tRNA methylation
0.34	GO:0019319	hexose biosynthetic process
0.34	GO:0006006	glucose metabolic process
0.33	GO:0055085	transmembrane transport

0.51	GO:0015367	oxoglutarate:malate antiporter activity
0.38	GO:0016429	tRNA (adenine-N1-)-methyltransferase activity
0.34	GO:0003779	actin binding
0.34	GO:0003723	RNA binding

0.51	GO:0031966	mitochondrial membrane
0.45	GO:0019866	organelle inner membrane
0.38	GO:0031515	tRNA (m1A) methyltransferase complex
0.34	GO:0005634	nucleus
0.33	GO:0005887	integral component of plasma membrane
0.33	GO:0019013	viral nucleocapsid
0.32	GO:0030529	intracellular ribonucleoprotein complex

0.38

GO:0016429

sp|P22300|GBRG2_BOVIN
Gamma-aminobutyric acid receptor subunit gamma-2
Search

GABRG2

0.95	Gamma-aminobutyric acid receptor subunit epsilon

0.85	GO:0007214	gamma-aminobutyric acid signaling pathway
0.77	GO:0006821	chloride transport
0.60	GO:0034220	ion transmembrane transport
0.56	GO:0071420	cellular response to histamine
0.52	GO:0030534	adult behavior
0.50	GO:0009791	post-embryonic development
0.50	GO:0007268	chemical synaptic transmission

0.84	GO:0004890	GABA-A receptor activity
0.75	GO:0005230	extracellular ligand-gated ion channel activity
0.50	GO:0005254	chloride channel activity
0.36	GO:0008503	benzodiazepine receptor activity
0.35	GO:0005515	protein binding

0.55	GO:1902711	GABA-A receptor complex
0.55	GO:0005886	plasma membrane
0.51	GO:0030424	axon
0.41	GO:0034707	chloride channel complex
0.40	GO:0098794	postsynapse
0.39	GO:0030425	dendrite
0.39	GO:0030054	cell junction
0.39	GO:0030659	cytoplasmic vesicle membrane
0.37	GO:0060077	inhibitory synapse
0.36	GO:0031252	cell leading edge

sp|P22439|ODPX_BOVIN
Pyruvate dehydrogenase protein X component
Search

PDHX

0.42	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex

0.55	GO:0006086	acetyl-CoA biosynthetic process from pyruvate
0.36	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate
0.35	GO:0019362	pyridine nucleotide metabolic process

0.62	GO:0016746	transferase activity, transferring acyl groups
0.60	GO:0034604	pyruvate dehydrogenase (NAD+) activity
0.37	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0005515	protein binding

0.56	GO:0045254	pyruvate dehydrogenase complex
0.46	GO:0005739	mitochondrion
0.41	GO:0031974	membrane-enclosed lumen
0.38	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.62	EC:2.3	GO:0016746
0.60	KEGG:R00209	GO:0034604

sp|P22444|BMP3_BOVIN
Bone morphogenetic protein 3
Search

BMP3

0.96	Bone morphogenetic protein 3

0.74	GO:0010469	regulation of receptor activity
0.72	GO:0001649	osteoblast differentiation
0.53	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
0.49	GO:0060395	SMAD protein signal transduction
0.49	GO:0030509	BMP signaling pathway
0.47	GO:0043408	regulation of MAPK cascade
0.46	GO:0048856	anatomical structure development
0.45	GO:0042981	regulation of apoptotic process
0.43	GO:0045668	negative regulation of osteoblast differentiation
0.43	GO:0045444	fat cell differentiation

0.77	GO:0008083	growth factor activity
0.65	GO:0005125	cytokine activity
0.61	GO:0070700	BMP receptor binding
0.49	GO:0005160	transforming growth factor beta receptor binding
0.35	GO:0016015	morphogen activity

0.65	GO:0005576	extracellular region
0.36	GO:0031982	vesicle
0.30	GO:0016020	membrane

sp|P22457|FA7_BOVIN
Coagulation factor VII
Search

0.82	Coagulation factor VII

0.79	GO:0007596	blood coagulation
0.61	GO:0006508	proteolysis
0.60	GO:0010641	positive regulation of platelet-derived growth factor receptor signaling pathway
0.58	GO:0050927	positive regulation of positive chemotaxis
0.57	GO:0051897	positive regulation of protein kinase B signaling
0.57	GO:0002690	positive regulation of leukocyte chemotaxis
0.50	GO:0051604	protein maturation
0.43	GO:1905217	response to astaxanthin
0.43	GO:1904400	response to Thyroid stimulating hormone
0.43	GO:1905225	response to thyrotropin-releasing hormone

0.69	GO:0004252	serine-type endopeptidase activity
0.69	GO:0005509	calcium ion binding
0.38	GO:0005102	receptor binding
0.37	GO:0005089	Rho guanyl-nucleotide exchange factor activity

0.65	GO:0005576	extracellular region
0.60	GO:1905286	serine-type peptidase complex
0.38	GO:0031982	vesicle
0.36	GO:0005796	Golgi lumen
0.35	GO:0005788	endoplasmic reticulum lumen
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.69

GO:0004252

sp|P22571|CNCG_BOVIN
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma
Search

PDE6H

0.96	Cone phosphodiesterase beta subunit

0.76	GO:0007601	visual perception
0.51	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway
0.51	GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway
0.50	GO:0000187	activation of MAPK activity
0.38	GO:0050896	response to stimulus
0.36	GO:0043086	negative regulation of catalytic activity
0.36	GO:0022400	regulation of rhodopsin mediated signaling pathway
0.34	GO:0198738	cell-cell signaling by wnt

0.85	GO:0030553	cGMP binding
0.77	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.38	GO:0030507	spectrin binding
0.36	GO:0004857	enzyme inhibitor activity
0.33	GO:0008270	zinc ion binding

0.38	GO:0097381	photoreceptor disc membrane
0.35	GO:0042622	photoreceptor outer segment membrane

0.77

GO:0004114

sp|P22600|HEMH_BOVIN
Ferrochelatase, mitochondrial
Search

FECH

0.55	Ferrochelatase

0.71	GO:0006783	heme biosynthetic process
0.49	GO:0046501	protoporphyrinogen IX metabolic process
0.39	GO:0030218	erythrocyte differentiation
0.38	GO:0070541	response to platinum ion
0.38	GO:0010288	response to lead ion
0.38	GO:0061515	myeloid cell development
0.38	GO:0051597	response to methylmercury
0.38	GO:0017085	response to insecticide
0.37	GO:0071549	cellular response to dexamethasone stimulus
0.37	GO:0071695	anatomical structure maturation

0.76	GO:0004325	ferrochelatase activity
0.36	GO:0030350	iron-responsive element binding
0.33	GO:0020037	heme binding
0.33	GO:0005506	iron ion binding
0.32	GO:0005509	calcium ion binding

0.39	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

0.76	EC:4.99.1.1	GO:0004325
0.76	KEGG:R00310	GO:0004325

sp|P22779|CP2AX_BOVIN
Cytochrome P450 2A (Fragment)
Search

sp|P23004|QCR2_BOVIN
Cytochrome b-c1 complex subunit 2, mitochondrial
Search

UQCRC2

0.84	Ubiquinol-cytochrome c reductase core protein II

0.52	GO:0006627	protein processing involved in protein targeting to mitochondrion
0.34	GO:0022900	electron transport chain

0.59	GO:0004222	metalloendopeptidase activity
0.54	GO:0046872	metal ion binding
0.36	GO:0016681	oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor
0.34	GO:0009055	electron transfer activity

0.60	GO:0005750	mitochondrial respiratory chain complex III
0.59	GO:0043209	myelin sheath
0.59	GO:0005751	mitochondrial respiratory chain complex IV
0.51	GO:0005654	nucleoplasm

0.59

GO:0004222

sp|P23005|CRGF_BOVIN
Gamma-crystallin F
Search

0.96	Gamma-crystallin F

0.77	GO:0002088	lens development in camera-type eye
0.62	GO:0030855	epithelial cell differentiation
0.61	GO:0007601	visual perception
0.57	GO:0048593	camera-type eye morphogenesis
0.54	GO:0000904	cell morphogenesis involved in differentiation
0.51	GO:0034614	cellular response to reactive oxygen species
0.42	GO:0043434	response to peptide hormone
0.36	GO:0006102	isocitrate metabolic process
0.33	GO:0055114	oxidation-reduction process

0.76	GO:0005212	structural constituent of eye lens
0.36	GO:0004450	isocitrate dehydrogenase (NADP+) activity
0.35	GO:0005515	protein binding
0.35	GO:0051287	NAD binding
0.34	GO:0000287	magnesium ion binding

0.54	GO:0005634	nucleus
0.44	GO:0005737	cytoplasm

0.36

GO:0004450

sp|P23132|LITH_BOVIN
Lithostathine
Search

0.97	Pancreatic beta cell growth factor

0.68	GO:0044278	cell wall disruption in other organism
0.63	GO:0045617	negative regulation of keratinocyte differentiation
0.63	GO:0010838	positive regulation of keratinocyte proliferation
0.63	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.60	GO:0090303	positive regulation of wound healing
0.60	GO:0051715	cytolysis in other organism
0.59	GO:0050830	defense response to Gram-positive bacterium
0.58	GO:0006953	acute-phase response
0.57	GO:0050829	defense response to Gram-negative bacterium
0.50	GO:0002755	MyD88-dependent toll-like receptor signaling pathway

0.63	GO:0070492	oligosaccharide binding
0.58	GO:0005539	glycosaminoglycan binding
0.53	GO:0042802	identical protein binding
0.45	GO:2001065	mannan binding
0.41	GO:0019903	protein phosphatase binding
0.40	GO:0008083	growth factor activity
0.39	GO:0019838	growth factor binding
0.39	GO:1901681	sulfur compound binding
0.38	GO:0046983	protein dimerization activity
0.36	GO:0005509	calcium ion binding

0.53	GO:0005576	extracellular region
0.52	GO:0030141	secretory granule
0.42	GO:0032809	neuronal cell body membrane
0.42	GO:0032590	dendrite membrane
0.42	GO:0044216	other organism cell
0.41	GO:0045178	basal part of cell
0.41	GO:0030426	growth cone
0.40	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0045177	apical part of cell
0.38	GO:0043234	protein complex

sp|P23196|APEX1_BOVIN
DNA-(apurinic or apyrimidinic site) lyase
Search

APEX1

0.65	DNA-(apurinic or apyrimidinic site) lyase

0.64	GO:0006281	DNA repair
0.64	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.57	GO:0043247	telomere maintenance in response to DNA damage
0.56	GO:0080111	DNA demethylation
0.56	GO:0043488	regulation of mRNA stability
0.51	GO:0042981	regulation of apoptotic process
0.48	GO:0045454	cell redox homeostasis
0.43	GO:1903506	regulation of nucleic acid-templated transcription
0.42	GO:0014912	negative regulation of smooth muscle cell migration
0.41	GO:0071320	cellular response to cAMP

0.77	GO:0140080	class III/IV DNA-(apurinic or apyrimidinic site) lyase activity
0.77	GO:0140078	class I DNA-(apurinic or apyrimidinic site) lyase activity
0.65	GO:0004519	endonuclease activity
0.58	GO:0008309	double-stranded DNA exodeoxyribonuclease activity
0.56	GO:0003691	double-stranded telomeric DNA binding
0.55	GO:0031490	chromatin DNA binding
0.53	GO:0046872	metal ion binding
0.53	GO:0003713	transcription coactivator activity
0.52	GO:0008408	3'-5' exonuclease activity
0.50	GO:0003684	damaged DNA binding

0.58	GO:0005634	nucleus
0.58	GO:0005739	mitochondrion
0.53	GO:0048471	perinuclear region of cytoplasm
0.52	GO:0005813	centrosome
0.48	GO:0031974	membrane-enclosed lumen
0.41	GO:0005783	endoplasmic reticulum
0.39	GO:0005667	transcription factor complex
0.35	GO:0000781	chromosome, telomeric region
0.33	GO:0005840	ribosome

0.50

GO:0008081

sp|P23206|COAA1_BOVIN
Collagen alpha-1(X) chain
Search

COL10A1

0.90	Collagen type VIII alpha 1 chain

0.43	GO:0009653	anatomical structure morphogenesis
0.43	GO:0007275	multicellular organism development
0.43	GO:0050673	epithelial cell proliferation
0.42	GO:0007492	endoderm development
0.41	GO:0010811	positive regulation of cell-substrate adhesion
0.39	GO:0030154	cell differentiation
0.39	GO:0036075	replacement ossification
0.38	GO:0061448	connective tissue development
0.35	GO:0007155	cell adhesion
0.34	GO:0030574	collagen catabolic process

0.37	GO:0005201	extracellular matrix structural constituent
0.33	GO:0005515	protein binding
0.32	GO:0046872	metal ion binding

0.79	GO:0005581	collagen trimer
0.61	GO:0005576	extracellular region
0.50	GO:0005938	cell cortex
0.36	GO:0043235	receptor complex
0.34	GO:0005788	endoplasmic reticulum lumen

sp|P23356|UCHL1_BOVIN
Ubiquitin carboxyl-terminal hydrolase isozyme L1
Search

UCHL1

0.55	Ubiquitin carboxyl-terminal hydrolase

0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.72	GO:0016579	protein deubiquitination
0.55	GO:0007412	axon target recognition
0.55	GO:0019896	axonal transport of mitochondrion
0.54	GO:0042755	eating behavior
0.54	GO:0002931	response to ischemia
0.54	GO:0007628	adult walking behavior
0.53	GO:0043407	negative regulation of MAP kinase activity
0.52	GO:0048747	muscle fiber development
0.52	GO:0050905	neuromuscular process

0.79	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.59	GO:0016874	ligase activity
0.57	GO:0031694	alpha-2A adrenergic receptor binding
0.53	GO:0043130	ubiquitin binding
0.51	GO:0031625	ubiquitin protein ligase binding
0.50	GO:0008242	omega peptidase activity
0.49	GO:0004197	cysteine-type endopeptidase activity

0.53	GO:1904115	axon cytoplasm
0.52	GO:0044306	neuron projection terminus
0.51	GO:0043209	myelin sheath
0.51	GO:0043025	neuronal cell body
0.48	GO:0005829	cytosol
0.48	GO:0005654	nucleoplasm
0.41	GO:0005886	plasma membrane
0.40	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0070062	extracellular exosome
0.34	GO:0043196	varicosity

0.59

GO:0016874

sp|P23389|SCG1_BOVIN
Secretogranin-1
Search

CHGB

0.95	Secretogranin I

0.37	GO:0006887	exocytosis
0.36	GO:0043687	post-translational protein modification
0.35	GO:0010469	regulation of receptor activity

0.36

GO:0005179

hormone activity

0.81	GO:0030141	secretory granule
0.40	GO:0005576	extracellular region
0.39	GO:0030658	transport vesicle membrane
0.36	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0031224	intrinsic component of membrane

sp|P23439|PDE6B_BOVIN
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta
Search

PDE6B

0.54	Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta

0.61	GO:0007165	signal transduction
0.58	GO:0051480	regulation of cytosolic calcium ion concentration
0.56	GO:0007601	visual perception
0.55	GO:0046037	GMP metabolic process
0.49	GO:0060041	retina development in camera-type eye
0.47	GO:0009583	detection of light stimulus
0.37	GO:0022400	regulation of rhodopsin mediated signaling pathway
0.36	GO:0045494	photoreceptor cell maintenance
0.36	GO:0071482	cellular response to light stimulus
0.35	GO:0198738	cell-cell signaling by wnt

0.79	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.54	GO:0046872	metal ion binding

0.50	GO:0001750	photoreceptor outer segment
0.39	GO:0060170	ciliary membrane

0.79

GO:0004114

sp|P23709|NDUS3_BOVIN
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial
Search

NDUFS3

0.91	NADH:ubiquinone oxidoreductase core subunit S3

0.73	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway
0.72	GO:0030308	negative regulation of cell growth
0.64	GO:0072593	reactive oxygen species metabolic process
0.53	GO:0055114	oxidation-reduction process
0.46	GO:0006091	generation of precursor metabolites and energy

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.78	GO:0005747	mitochondrial respiratory chain complex I
0.76	GO:0043209	myelin sheath
0.68	GO:0016604	nuclear body

0.69

GO:0008137

sp|P23726|P85B_BOVIN
Phosphatidylinositol 3-kinase regulatory subunit beta
Search

PIK3R2

0.86	Phosphatidylinositol 3-kinase regulatory subunit alpha

0.84	GO:0043551	regulation of phosphatidylinositol 3-kinase activity
0.59	GO:0007165	signal transduction
0.55	GO:0016310	phosphorylation
0.52	GO:2001275	positive regulation of glucose import in response to insulin stimulus
0.49	GO:0032869	cellular response to insulin stimulus
0.48	GO:0042993	positive regulation of transcription factor import into nucleus
0.46	GO:0001678	cellular glucose homeostasis
0.46	GO:1903076	regulation of protein localization to plasma membrane
0.46	GO:0051492	regulation of stress fiber assembly
0.46	GO:0034976	response to endoplasmic reticulum stress

0.85	GO:0035014	phosphatidylinositol 3-kinase regulator activity
0.57	GO:0016301	kinase activity
0.48	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding
0.44	GO:0046982	protein heterodimerization activity
0.42	GO:0008134	transcription factor binding
0.42	GO:0001784	phosphotyrosine residue binding
0.41	GO:0019903	protein phosphatase binding
0.41	GO:0030971	receptor tyrosine kinase binding
0.36	GO:0043125	ErbB-3 class receptor binding
0.36	GO:0005096	GTPase activator activity

0.82	GO:0005942	phosphatidylinositol 3-kinase complex
0.44	GO:0005925	focal adhesion
0.40	GO:0005634	nucleus
0.37	GO:0005829	cytosol
0.36	GO:1990578	perinuclear endoplasmic reticulum membrane
0.35	GO:0005801	cis-Golgi network
0.34	GO:0005911	cell-cell junction
0.33	GO:0043234	protein complex

0.34

GO:0016773

sp|P23727|P85A_BOVIN
Phosphatidylinositol 3-kinase regulatory subunit alpha
Search

PIK3R1

0.92	Phosphatidylinositol 3-kinase regulatory subunit alpha

0.85	GO:0043551	regulation of phosphatidylinositol 3-kinase activity
0.58	GO:1900076	regulation of cellular response to insulin stimulus
0.57	GO:0007165	signal transduction
0.57	GO:1900103	positive regulation of endoplasmic reticulum unfolded protein response
0.57	GO:0051531	NFAT protein import into nucleus
0.56	GO:0046326	positive regulation of glucose import
0.56	GO:0033120	positive regulation of RNA splicing
0.55	GO:0042993	positive regulation of transcription factor import into nucleus
0.55	GO:0032869	cellular response to insulin stimulus
0.55	GO:0071378	cellular response to growth hormone stimulus

0.85	GO:0035014	phosphatidylinositol 3-kinase regulator activity
0.58	GO:0043125	ErbB-3 class receptor binding
0.57	GO:0043559	insulin binding
0.57	GO:0005168	neurotrophin TRKA receptor binding
0.56	GO:0005159	insulin-like growth factor receptor binding
0.55	GO:0005158	insulin receptor binding
0.55	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding
0.55	GO:0043560	insulin receptor substrate binding
0.54	GO:0001784	phosphotyrosine residue binding
0.53	GO:0016301	kinase activity

0.83	GO:0005942	phosphatidylinositol 3-kinase complex
0.56	GO:1990578	perinuclear endoplasmic reticulum membrane
0.51	GO:0005801	cis-Golgi network
0.49	GO:0005911	cell-cell junction
0.46	GO:0005829	cytosol
0.43	GO:0005634	nucleus
0.42	GO:0043234	protein complex
0.34	GO:0043005	neuron projection
0.33	GO:0005886	plasma membrane

0.35

GO:0016773

sp|P23795|ACES_BOVIN
Acetylcholinesterase
Search

ACHE

0.44	Carboxylic ester hydrolase

0.60	GO:0006581	acetylcholine catabolic process
0.56	GO:0045212	neurotransmitter receptor biosynthetic process
0.55	GO:0002076	osteoblast development
0.52	GO:0001919	regulation of receptor recycling
0.52	GO:0031623	receptor internalization
0.51	GO:0060041	retina development in camera-type eye
0.50	GO:0051262	protein tetramerization
0.48	GO:0007155	cell adhesion
0.44	GO:0071405	cellular response to methanol
0.42	GO:0050808	synapse organization

0.84	GO:0004104	cholinesterase activity
0.55	GO:0042166	acetylcholine binding
0.54	GO:0043236	laminin binding
0.52	GO:0005518	collagen binding
0.52	GO:0043621	protein self-association
0.51	GO:0042802	identical protein binding
0.46	GO:0046983	protein dimerization activity
0.46	GO:0017171	serine hydrolase activity
0.38	GO:0001540	amyloid-beta binding
0.36	GO:0033265	choline binding

0.53	GO:0005605	basal lamina
0.52	GO:0045202	synapse
0.51	GO:0048471	perinuclear region of cytoplasm
0.48	GO:0012505	endomembrane system
0.48	GO:0009986	cell surface
0.47	GO:0005615	extracellular space
0.42	GO:0043231	intracellular membrane-bounded organelle
0.42	GO:0030054	cell junction
0.42	GO:0005886	plasma membrane
0.41	GO:0031970	organelle envelope lumen

0.84

EC:3.1.1.8

GO:0004104

sp|P23805|CONG_BOVIN
Conglutinin
Search

SFTPD

0.96	Pulmonary surfactant-associated protein D

0.56	GO:1905226	regulation of adhesion of symbiont to host epithelial cell
0.55	GO:0043129	surfactant homeostasis
0.55	GO:0043152	induction of bacterial agglutination
0.55	GO:0052405	negative regulation by host of symbiont molecular function
0.54	GO:0048286	lung alveolus development
0.44	GO:0071230	cellular response to amino acid stimulus
0.44	GO:0030198	extracellular matrix organization
0.43	GO:0009888	tissue development
0.43	GO:0007585	respiratory gaseous exchange
0.43	GO:0009653	anatomical structure morphogenesis

0.56	GO:0005201	extracellular matrix structural constituent
0.44	GO:0048407	platelet-derived growth factor binding
0.44	GO:0042802	identical protein binding
0.43	GO:0002020	protease binding
0.42	GO:0030246	carbohydrate binding
0.41	GO:0042302	structural constituent of cuticle
0.38	GO:0005178	integrin binding
0.37	GO:0046332	SMAD binding
0.37	GO:0030414	peptidase inhibitor activity
0.37	GO:0061135	endopeptidase regulator activity

0.71	GO:0005581	collagen trimer
0.51	GO:0031012	extracellular matrix
0.46	GO:0005615	extracellular space
0.41	GO:0099081	supramolecular polymer
0.37	GO:0005783	endoplasmic reticulum
0.37	GO:0031982	vesicle
0.35	GO:0005764	lysosome
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0031984	organelle subcompartment
0.34	GO:0019867	outer membrane

0.32

GO:0004222

sp|P23934|NDUS6_BOVIN
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial
Search

NDUFS6

0.93	Mitochondrial NADH dehydrogenase [ubiquinone] iron-sulfur protein 6

0.69	GO:0006120	mitochondrial electron transport, NADH to ubiquinone
0.54	GO:0070584	mitochondrion morphogenesis
0.52	GO:0035264	multicellular organism growth
0.52	GO:0010259	multicellular organism aging
0.51	GO:0006936	muscle contraction
0.50	GO:0072358	cardiovascular system development
0.50	GO:0061458	reproductive system development
0.46	GO:0006631	fatty acid metabolic process
0.35	GO:0032981	mitochondrial respiratory chain complex I assembly

0.34	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.33	GO:0009055	electron transfer activity

0.75

GO:0005747

mitochondrial respiratory chain complex I

0.34

GO:0008137

sp|P23935|NDUA5_BOVIN
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5
Search

NDUFA5

0.41	NADH dehydrogenase 1 alpha subcomplex subunit 5

0.67	GO:0022904	respiratory electron transport chain
0.53	GO:0032981	mitochondrial respiratory chain complex I assembly
0.33	GO:0006119	oxidative phosphorylation

0.66	GO:0016651	oxidoreductase activity, acting on NAD(P)H
0.33	GO:0005515	protein binding
0.32	GO:0003676	nucleic acid binding

0.61	GO:0031966	mitochondrial membrane
0.61	GO:0019866	organelle inner membrane
0.52	GO:0045271	respiratory chain complex I
0.49	GO:0098798	mitochondrial protein complex
0.47	GO:1990204	oxidoreductase complex
0.30	GO:0016021	integral component of membrane

0.66

GO:0016651

sp|P23956|VATL_BOVIN
V-type proton ATPase 16 kDa proteolipid subunit
Search

ATP6V0C

0.61	V-type proton ATPase proteolipid subunit

0.76	GO:0015991	ATP hydrolysis coupled proton transport
0.51	GO:0030177	positive regulation of Wnt signaling pathway
0.51	GO:0007042	lysosomal lumen acidification
0.41	GO:0060036	notochord cell vacuolation
0.40	GO:0001878	response to yeast
0.40	GO:0060059	embryonic retina morphogenesis in camera-type eye
0.35	GO:0090383	phagosome acidification
0.35	GO:0033572	transferrin transport
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0008286	insulin receptor signaling pathway

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.49	GO:0031625	ubiquitin protein ligase binding
0.47	GO:0036442	proton-exporting ATPase activity
0.44	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
0.34	GO:0005245	voltage-gated calcium channel activity
0.34	GO:0015662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
0.34	GO:0008448	N-acetylglucosamine-6-phosphate deacetylase activity

0.78	GO:0033179	proton-transporting V-type ATPase, V0 domain
0.76	GO:0005774	vacuolar membrane
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.36	GO:0005764	lysosome
0.36	GO:0099503	secretory vesicle
0.35	GO:0012505	endomembrane system
0.35	GO:0030670	phagocytic vesicle membrane
0.34	GO:0048786	presynaptic active zone
0.32	GO:0005886	plasma membrane

0.34

EC:3.5.1.25

GO:0008448

sp|P24275|AKAP5_BOVIN
A-kinase anchor protein 5
Search

AKAP5

0.96	A-kinase anchoring protein 5

0.84	GO:0010738	regulation of protein kinase A signaling
0.82	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.70	GO:0006605	protein targeting
0.45	GO:0033159	negative regulation of protein import into nucleus, translocation
0.45	GO:1903538	regulation of meiotic cell cycle process involved in oocyte maturation

0.86	GO:0030346	protein phosphatase 2B binding
0.85	GO:0008179	adenylate cyclase binding
0.85	GO:0035254	glutamate receptor binding
0.84	GO:0034237	protein kinase A regulatory subunit binding
0.84	GO:0097110	scaffold protein binding
0.77	GO:0017124	SH3 domain binding

0.45	GO:0005622	intracellular
0.36	GO:0005886	plasma membrane

sp|P24591|IBP1_BOVIN
Insulin-like growth factor-binding protein 1
Search

IGFBP1

0.97	Insulin like growth factor binding protein 1

0.76	GO:0001558	regulation of cell growth
0.51	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway
0.45	GO:0031099	regeneration
0.41	GO:0001666	response to hypoxia
0.41	GO:0008285	negative regulation of cell proliferation
0.40	GO:0008286	insulin receptor signaling pathway
0.39	GO:0045927	positive regulation of growth
0.39	GO:0007568	aging
0.39	GO:0042060	wound healing
0.39	GO:0048589	developmental growth

0.84	GO:0005520	insulin-like growth factor binding
0.35	GO:0005102	receptor binding
0.33	GO:0035718	macrophage migration inhibitory factor binding
0.33	GO:0023026	MHC class II protein complex binding
0.32	GO:0050998	nitric-oxide synthase binding
0.32	GO:0001540	amyloid-beta binding
0.32	GO:0044183	protein binding involved in protein folding
0.32	GO:0004896	cytokine receptor activity

0.66	GO:0005576	extracellular region
0.52	GO:0005794	Golgi apparatus
0.36	GO:0005788	endoplasmic reticulum lumen
0.33	GO:0035693	NOS2-CD74 complex
0.33	GO:0035692	macrophage migration inhibitory factor receptor complex
0.32	GO:0031982	vesicle
0.32	GO:0009897	external side of plasma membrane
0.32	GO:0005764	lysosome
0.32	GO:0042613	MHC class II protein complex
0.30	GO:0016021	integral component of membrane

sp|P24627|TRFL_BOVIN
Lactotransferrin
Search

0.79	Inhibitor of carbonic anhydrase

0.83	GO:0019732	antifungal humoral response
0.81	GO:0019731	antibacterial humoral response
0.74	GO:0001817	regulation of cytokine production
0.57	GO:0006508	proteolysis
0.57	GO:1900229	negative regulation of single-species biofilm formation in or on host organism
0.56	GO:1902732	positive regulation of chondrocyte proliferation
0.55	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway
0.55	GO:0002227	innate immune response in mucosa
0.55	GO:0033690	positive regulation of osteoblast proliferation
0.54	GO:0044793	negative regulation by host of viral process

0.65	GO:0004252	serine-type endopeptidase activity
0.61	GO:0005506	iron ion binding
0.51	GO:0043539	protein serine/threonine kinase activator activity
0.50	GO:0008201	heparin binding
0.50	GO:0004857	enzyme inhibitor activity
0.50	GO:0001530	lipopolysaccharide binding
0.48	GO:0061135	endopeptidase regulator activity
0.47	GO:0015091	ferric iron transmembrane transporter activity
0.40	GO:1990459	transferrin receptor binding
0.37	GO:0005525	GTP binding

0.71	GO:0005615	extracellular space
0.54	GO:0042581	specific granule
0.49	GO:0009986	cell surface
0.44	GO:0044218	other organism cell membrane
0.41	GO:0043234	protein complex
0.40	GO:1990712	HFE-transferrin receptor complex
0.40	GO:0009925	basal plasma membrane
0.39	GO:0055037	recycling endosome
0.39	GO:0016324	apical plasma membrane
0.39	GO:0030139	endocytic vesicle

0.65

GO:0004252

sp|P25068|TAP_BOVIN
Tracheal antimicrobial peptide
Search

0.50	Beta-defensin 1

0.78	GO:0042742	defense response to bacterium
0.56	GO:0060474	positive regulation of flagellated sperm motility involved in capacitation
0.54	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.52	GO:0019933	cAMP-mediated signaling

0.56	GO:0031731	CCR6 chemokine receptor binding
0.48	GO:0042802	identical protein binding

0.66	GO:0005576	extracellular region
0.54	GO:0097225	sperm midpiece
0.48	GO:0019898	extrinsic component of membrane
0.47	GO:0031982	vesicle
0.36	GO:0005622	intracellular

sp|P25104|AGTR1_BOVIN
Type-1 angiotensin II receptor
Search

AGTR1

0.97	Type-1 angiotensin II receptor

0.83	GO:0038166	angiotensin-activated signaling pathway
0.81	GO:0019229	regulation of vasoconstriction
0.42	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.41	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.41	GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin
0.40	GO:0042756	drinking behavior
0.40	GO:0003071	renal system process involved in regulation of systemic arterial blood pressure
0.40	GO:0071549	cellular response to dexamethasone stimulus
0.40	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis
0.40	GO:0045777	positive regulation of blood pressure

0.85	GO:0004945	angiotensin type II receptor activity
0.43	GO:0001596	angiotensin type I receptor activity
0.40	GO:0031711	bradykinin receptor binding
0.40	GO:0017046	peptide hormone binding
0.39	GO:0043621	protein self-association
0.38	GO:0031748	D1 dopamine receptor binding
0.37	GO:0001965	G-protein alpha-subunit binding
0.37	GO:0046982	protein heterodimerization activity
0.36	GO:0019901	protein kinase binding

0.40	GO:0031983	vesicle lumen
0.39	GO:0016323	basolateral plasma membrane
0.38	GO:0012506	vesicle membrane
0.36	GO:0055037	recycling endosome
0.36	GO:0030425	dendrite
0.36	GO:0031968	organelle outer membrane
0.35	GO:0005794	Golgi apparatus
0.33	GO:0005887	integral component of plasma membrane

sp|P25285|GCST_BOVIN
Aminomethyltransferase, mitochondrial
Search

AMT

0.54	Aminomethyltransferase, mitochondrial

0.74	GO:0006546	glycine catabolic process
0.62	GO:0032259	methylation
0.33	GO:0007264	small GTPase mediated signal transduction

0.78	GO:0004047	aminomethyltransferase activity
0.66	GO:0008483	transaminase activity
0.37	GO:0031405	lipoic acid binding
0.32	GO:0003924	GTPase activity
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.59	GO:0005739	mitochondrion
0.50	GO:0005654	nucleoplasm
0.33	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

0.78

EC:2.1.2.10

GO:0004047

sp|P25326|CATS_BOVIN
Cathepsin S
Search

CTSS

0.89	LOW QUALITY PROTEIN: cathepsin S

0.63	GO:0034769	basement membrane disassembly
0.60	GO:0030574	collagen catabolic process
0.60	GO:0006508	proteolysis
0.60	GO:0097067	cellular response to thyroid hormone stimulus
0.58	GO:2001259	positive regulation of cation channel activity
0.58	GO:0010447	response to acidic pH
0.56	GO:0002250	adaptive immune response
0.56	GO:0048002	antigen processing and presentation of peptide antigen
0.53	GO:0044257	cellular protein catabolic process
0.51	GO:0051604	protein maturation

0.71	GO:0008234	cysteine-type peptidase activity
0.61	GO:0001968	fibronectin binding
0.60	GO:0043394	proteoglycan binding
0.59	GO:0043236	laminin binding
0.58	GO:0005518	collagen binding
0.49	GO:0004175	endopeptidase activity
0.35	GO:0017171	serine hydrolase activity

0.57	GO:0005764	lysosome
0.54	GO:0005615	extracellular space
0.38	GO:0031904	endosome lumen
0.37	GO:0005654	nucleoplasm
0.36	GO:1904724	tertiary granule lumen
0.36	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0005775	vacuolar lumen
0.35	GO:0005769	early endosome
0.34	GO:0009986	cell surface
0.30	GO:0016020	membrane

0.71

GO:0008234

sp|P25417|CYTB_BOVIN
Cystatin-B
Search

CSTB

0.91	LOW QUALITY PROTEIN: cystatin-B

0.76	GO:0010951	negative regulation of endopeptidase activity
0.49	GO:0008344	adult locomotory behavior
0.36	GO:0043312	neutrophil degranulation
0.34	GO:0030216	keratinocyte differentiation
0.34	GO:0018149	peptide cross-linking
0.34	GO:0098609	cell-cell adhesion
0.33	GO:0043043	peptide biosynthetic process
0.33	GO:0007186	G-protein coupled receptor signaling pathway
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process

0.82	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.52	GO:0002020	protease binding
0.34	GO:0030674	protein binding, bridging
0.34	GO:0003723	RNA binding
0.34	GO:0005198	structural molecule activity
0.33	GO:0004930	G-protein coupled receptor activity

0.48	GO:0005730	nucleolus
0.48	GO:0005615	extracellular space
0.46	GO:0005829	cytosol
0.37	GO:1903561	extracellular vesicle
0.36	GO:1904724	tertiary granule lumen
0.36	GO:1904813	ficolin-1-rich granule lumen
0.36	GO:0034774	secretory granule lumen
0.35	GO:0001533	cornified envelope
0.33	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

sp|P25500|PAPOA_BOVIN
Poly(A) polymerase alpha
Search

PAPOLA

0.60	Poly (A) polymerase alpha

0.78	GO:0043631	RNA polyadenylation
0.74	GO:0031123	RNA 3'-end processing
0.52	GO:0031440	regulation of mRNA 3'-end processing
0.47	GO:0006397	mRNA processing
0.35	GO:0006369	termination of RNA polymerase II transcription
0.34	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile

0.76	GO:0004652	polynucleotide adenylyltransferase activity
0.58	GO:0003723	RNA binding
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0046872	metal ion binding
0.35	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.44	GO:0031974	membrane-enclosed lumen
0.41	GO:0044446	intracellular organelle part
0.36	GO:0005737	cytoplasm
0.34	GO:0012505	endomembrane system
0.30	GO:0031224	intrinsic component of membrane

0.76

EC:2.7.7.19

GO:0004652

sp|P25508|COCA1_BOVIN
Collagen alpha-1(XII) chain (Fragments)
Search

0.11	Collagen alpha-1(XII) chain (Fragments)

0.58	GO:0035987	endodermal cell differentiation
0.44	GO:0007155	cell adhesion
0.36	GO:0030574	collagen catabolic process
0.36	GO:0030199	collagen fibril organization
0.36	GO:1905812	regulation of motor neuron axon guidance
0.35	GO:0001501	skeletal system development
0.34	GO:0001654	eye development
0.33	GO:0010469	regulation of receptor activity

0.40	GO:0005198	structural molecule activity
0.34	GO:0005179	hormone activity

0.69	GO:0005581	collagen trimer
0.56	GO:0031012	extracellular matrix
0.53	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.36	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0031224	intrinsic component of membrane

sp|P25708|NDUV1_BOVIN
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
Search

NDUFV1

0.72	NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial

0.52	GO:0055114	oxidation-reduction process
0.44	GO:0006119	oxidative phosphorylation
0.35	GO:0032981	mitochondrial respiratory chain complex I assembly

0.69	GO:0010181	FMN binding
0.68	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.66	GO:0051539	4 iron, 4 sulfur cluster binding
0.65	GO:0051287	NAD binding
0.52	GO:0046872	metal ion binding
0.35	GO:0004364	glutathione transferase activity
0.33	GO:0005515	protein binding

0.60	GO:0070469	respiratory chain
0.60	GO:0031966	mitochondrial membrane
0.60	GO:0019866	organelle inner membrane
0.51	GO:0030964	NADH dehydrogenase complex
0.48	GO:0098798	mitochondrial protein complex
0.47	GO:0005829	cytosol
0.47	GO:1990204	oxidoreductase complex
0.43	GO:0098796	membrane protein complex

0.68

GO:0008137

sp|P25712|NDUV3_BOVIN
NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial
Search

NDUFV3

0.95	NADH dehydrogenase flavoprotein 3, mitochondrial

0.42	GO:0042775	mitochondrial ATP synthesis coupled electron transport
0.37	GO:0032981	mitochondrial respiratory chain complex I assembly
0.33	GO:0007165	signal transduction

0.35	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.35	GO:0003723	RNA binding
0.35	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.33	GO:0046872	metal ion binding

0.82	GO:0005747	mitochondrial respiratory chain complex I
0.41	GO:0005654	nucleoplasm

0.35

GO:0008137

sp|P25930|CXCR4_BOVIN
C-X-C chemokine receptor type 4
Search

CXCR4

0.71	C-X-C motif chemokine receptor 4

0.81	GO:0070098	chemokine-mediated signaling pathway
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.69	GO:0006935	chemotaxis
0.52	GO:0019722	calcium-mediated signaling
0.51	GO:0001666	response to hypoxia
0.51	GO:0050920	regulation of chemotaxis
0.38	GO:0048714	positive regulation of oligodendrocyte differentiation
0.38	GO:0043217	myelin maintenance
0.37	GO:0016477	cell migration
0.37	GO:0007409	axonogenesis

0.82	GO:0004950	chemokine receptor activity
0.79	GO:0019955	cytokine binding
0.55	GO:0032027	myosin light chain binding
0.51	GO:0043130	ubiquitin binding
0.50	GO:0031625	ubiquitin protein ligase binding
0.48	GO:0003779	actin binding
0.35	GO:0001618	virus receptor activity
0.35	GO:0015026	coreceptor activity
0.32	GO:0008144	drug binding

0.53	GO:0005770	late endosome
0.53	GO:0005769	early endosome
0.53	GO:0005764	lysosome
0.51	GO:0031252	cell leading edge
0.49	GO:0009986	cell surface
0.44	GO:0030054	cell junction
0.42	GO:0043234	protein complex
0.42	GO:0005886	plasma membrane
0.36	GO:0030426	growth cone
0.36	GO:0070062	extracellular exosome

sp|P25975|CATL1_BOVIN
Cathepsin L1
Search

0.71	Cathepsin V

0.61	GO:0006508	proteolysis
0.50	GO:0010839	negative regulation of keratinocyte proliferation
0.50	GO:0046697	decidualization
0.49	GO:0031069	hair follicle morphogenesis
0.49	GO:2000249	regulation of actin cytoskeleton reorganization
0.47	GO:0044257	cellular protein catabolic process
0.45	GO:0097067	cellular response to thyroid hormone stimulus
0.44	GO:0030574	collagen catabolic process
0.44	GO:0051604	protein maturation
0.43	GO:0002250	adaptive immune response

0.72	GO:0008234	cysteine-type peptidase activity
0.50	GO:0042393	histone binding
0.47	GO:0097655	serpin family protein binding
0.45	GO:0004175	endopeptidase activity
0.45	GO:0001968	fibronectin binding
0.44	GO:0043394	proteoglycan binding
0.44	GO:0004180	carboxypeptidase activity
0.43	GO:0005518	collagen binding
0.41	GO:0030984	kininogen binding
0.39	GO:0042277	peptide binding

0.54	GO:0005764	lysosome
0.51	GO:0005615	extracellular space
0.44	GO:0031410	cytoplasmic vesicle
0.44	GO:0005730	nucleolus
0.40	GO:0043204	perikaryon
0.40	GO:0005902	microvillus
0.39	GO:0009897	external side of plasma membrane
0.39	GO:0045177	apical part of cell
0.38	GO:0043005	neuron projection
0.37	GO:0012505	endomembrane system

0.72

GO:0008234

sp|P26201|CD36_BOVIN
Platelet glycoprotein 4
Search

CD36

0.92	Platelet glycoprotein IV variant

0.74	GO:0006955	immune response
0.71	GO:0007166	cell surface receptor signaling pathway
0.55	GO:0071726	cellular response to diacyl bacterial lipopeptide
0.55	GO:0070543	response to linoleic acid
0.54	GO:0034197	triglyceride transport
0.54	GO:0044539	long-chain fatty acid import
0.54	GO:0055094	response to lipoprotein particle
0.54	GO:1900227	positive regulation of NLRP3 inflammasome complex assembly
0.54	GO:0071402	cellular response to lipoprotein particle stimulus
0.54	GO:0030299	intestinal cholesterol absorption

0.51	GO:0005041	low-density lipoprotein receptor activity
0.51	GO:0070892	lipoteichoic acid receptor activity
0.51	GO:0030169	low-density lipoprotein particle binding
0.51	GO:0035325	Toll-like receptor binding
0.50	GO:0008035	high-density lipoprotein particle binding
0.45	GO:0008289	lipid binding
0.43	GO:0070053	thrombospondin receptor activity
0.42	GO:0050431	transforming growth factor beta binding
0.38	GO:0001540	amyloid-beta binding
0.37	GO:0005044	scavenger receptor activity

0.51	GO:0031526	brush border membrane
0.50	GO:0098857	membrane microdomain
0.49	GO:0045177	apical part of cell
0.49	GO:0005794	Golgi apparatus
0.47	GO:0043235	receptor complex
0.46	GO:0009897	external side of plasma membrane
0.39	GO:0031092	platelet alpha granule membrane
0.39	GO:0035579	specific granule membrane
0.39	GO:0005615	extracellular space
0.38	GO:0042383	sarcolemma

sp|P26285|F262_BOVIN
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2
Search

PFKFB2

0.96	6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 2 transcript variant 3

0.83	GO:0006003	fructose 2,6-bisphosphate metabolic process
0.83	GO:0006000	fructose metabolic process
0.74	GO:0046835	carbohydrate phosphorylation
0.47	GO:0006757	ATP generation from ADP
0.46	GO:0006090	pyruvate metabolic process
0.46	GO:0016052	carbohydrate catabolic process
0.46	GO:0019362	pyridine nucleotide metabolic process
0.38	GO:0016311	dephosphorylation
0.37	GO:0033133	positive regulation of glucokinase activity
0.37	GO:0032024	positive regulation of insulin secretion

0.84	GO:0003873	6-phosphofructo-2-kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0019901	protein kinase binding
0.43	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity

0.46	GO:0005654	nucleoplasm
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.84	EC:2.7.1.105	GO:0003873
0.84	KEGG:R02732	GO:0003873

sp|P26377|STP2_BOVIN
Nuclear transition protein 2
Search

TNP2

0.97	Nuclear transition protein 2

0.80	GO:0007283	spermatogenesis
0.69	GO:0030154	cell differentiation
0.67	GO:0007275	multicellular organism development
0.61	GO:0007341	penetration of zona pellucida
0.60	GO:0010954	positive regulation of protein processing
0.59	GO:0007340	acrosome reaction
0.58	GO:0043486	histone exchange
0.57	GO:0006997	nucleus organization
0.55	GO:0022412	cellular process involved in reproduction in multicellular organism
0.54	GO:0003006	developmental process involved in reproduction

0.55	GO:0003677	DNA binding
0.52	GO:0046872	metal ion binding
0.36	GO:0005515	protein binding

0.75	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.49	GO:0031974	membrane-enclosed lumen

sp|P26444|CRBA2_BOVIN
Beta-crystallin A2
Search

CRYBA2

0.95	Beta-crystallin A2

0.68	GO:0002088	lens development in camera-type eye
0.60	GO:0007601	visual perception
0.35	GO:0006478	peptidyl-tyrosine sulfation

0.67	GO:0005212	structural constituent of eye lens
0.60	GO:0042803	protein homodimerization activity
0.35	GO:0008476	protein-tyrosine sulfotransferase activity

0.30

GO:0044425

membrane part

0.35

EC:2.8.2.20

GO:0008476

sp|P26452|RSSA_BOVIN
40S ribosomal protein SA
Search

RPSA

0.73	40S ribosomal protein SA

0.77	GO:0000028	ribosomal small subunit assembly
0.66	GO:0007155	cell adhesion
0.58	GO:0043043	peptide biosynthetic process
0.54	GO:0044267	cellular protein metabolic process
0.52	GO:0010467	gene expression
0.51	GO:0009059	macromolecule biosynthetic process
0.47	GO:0006407	rRNA export from nucleus
0.42	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.42	GO:0016072	rRNA metabolic process
0.37	GO:0030855	epithelial cell differentiation

0.85	GO:0005055	laminin receptor activity
0.79	GO:0043236	laminin binding
0.62	GO:0003735	structural constituent of ribosome
0.38	GO:0104005	hijacked molecular function
0.36	GO:0043022	ribosome binding
0.33	GO:0003723	RNA binding

0.74	GO:0022627	cytosolic small ribosomal subunit
0.58	GO:0005634	nucleus
0.53	GO:0005886	plasma membrane
0.45	GO:0030686	90S preribosome
0.37	GO:0005604	basement membrane
0.37	GO:0043025	neuronal cell body
0.36	GO:0070062	extracellular exosome
0.35	GO:0098556	cytoplasmic side of rough endoplasmic reticulum membrane
0.33	GO:0043233	organelle lumen

sp|P26779|SAP_BOVIN
Prosaposin
Search

PSAP

0.85	Proactivator polypeptide

0.79	GO:0006665	sphingolipid metabolic process
0.58	GO:0060742	epithelial cell differentiation involved in prostate gland development
0.58	GO:0060736	prostate gland growth
0.57	GO:1905572	ganglioside GM1 transport to membrane
0.55	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.55	GO:1901032	negative regulation of response to reactive oxygen species
0.55	GO:2001039	negative regulation of cellular response to drug
0.55	GO:1903205	regulation of hydrogen peroxide-induced cell death
0.54	GO:1903202	negative regulation of oxidative stress-induced cell death
0.53	GO:0019216	regulation of lipid metabolic process

0.58	GO:1905577	ganglioside GP1c binding
0.58	GO:1905574	ganglioside GM2 binding
0.58	GO:1905575	ganglioside GM3 binding
0.57	GO:1905573	ganglioside GM1 binding
0.57	GO:1905576	ganglioside GT1b binding
0.53	GO:0001664	G-protein coupled receptor binding
0.50	GO:0004565	beta-galactosidase activity
0.49	GO:0005543	phospholipid binding
0.49	GO:0042803	protein homodimerization activity
0.43	GO:0008047	enzyme activator activity

0.79	GO:0005764	lysosome
0.51	GO:0005615	extracellular space
0.48	GO:0031012	extracellular matrix
0.43	GO:0005739	mitochondrion
0.37	GO:1903561	extracellular vesicle
0.36	GO:0005775	vacuolar lumen
0.36	GO:0030667	secretory granule membrane
0.35	GO:0098852	lytic vacuole membrane
0.33	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

0.50

EC:3.2.1.23

GO:0004565

sp|P26818|ARBK2_BOVIN
Beta-adrenergic receptor kinase 2
Search

GRK3

0.69	G protein-coupled receptor kinase

0.63	GO:0006468	protein phosphorylation
0.61	GO:0007165	signal transduction
0.61	GO:0031623	receptor internalization
0.52	GO:0003108	negative regulation of the force of heart contraction by chemical signal
0.51	GO:0002029	desensitization of G-protein coupled receptor protein signaling pathway
0.51	GO:0045988	negative regulation of striated muscle contraction
0.49	GO:0007507	heart development
0.49	GO:0060048	cardiac muscle contraction
0.48	GO:0018210	peptidyl-threonine modification
0.47	GO:0018209	peptidyl-serine modification

0.85	GO:0004703	G-protein coupled receptor kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0031755	Edg-2 lysophosphatidic acid receptor binding
0.46	GO:0047696	beta-adrenergic receptor kinase activity
0.37	GO:0031694	alpha-2A adrenergic receptor binding
0.35	GO:0031748	D1 dopamine receptor binding
0.34	GO:0008138	protein tyrosine/serine/threonine phosphatase activity

0.37	GO:0005737	cytoplasm
0.37	GO:0120025	plasma membrane bounded cell projection
0.36	GO:0036477	somatodendritic compartment
0.35	GO:0098794	postsynapse
0.35	GO:0005886	plasma membrane
0.35	GO:0044463	cell projection part
0.34	GO:0097223	sperm part
0.34	GO:0098857	membrane microdomain
0.34	GO:0045177	apical part of cell
0.34	GO:0043226	organelle

0.85

GO:0004703

sp|P26882|PPID_BOVIN
Peptidyl-prolyl cis-trans isomerase D
Search

PPID

0.74	Peptidyl-prolyl cis-trans isomerase D

0.72	GO:0000413	protein peptidyl-prolyl isomerization
0.68	GO:0006457	protein folding
0.59	GO:0071492	cellular response to UV-A
0.56	GO:0045070	positive regulation of viral genome replication
0.56	GO:0034389	lipid particle organization
0.54	GO:0050714	positive regulation of protein secretion
0.53	GO:0042981	regulation of apoptotic process
0.52	GO:0043068	positive regulation of programmed cell death
0.52	GO:0000122	negative regulation of transcription by RNA polymerase II
0.48	GO:0006461	protein complex assembly

0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.56	GO:0051879	Hsp90 protein binding
0.50	GO:0008134	transcription factor binding
0.40	GO:0051427	hormone receptor binding
0.40	GO:0030544	Hsp70 protein binding
0.38	GO:0016018	cyclosporin A binding
0.35	GO:0005528	FK506 binding
0.34	GO:0043022	ribosome binding
0.34	GO:0019899	enzyme binding
0.34	GO:0051082	unfolded protein binding

0.50	GO:0005730	nucleolus
0.48	GO:0005829	cytosol
0.37	GO:0005654	nucleoplasm
0.33	GO:0005739	mitochondrion
0.32	GO:0043234	protein complex

0.72

GO:0003755

sp|P26884|FKBP3_BOVIN
Peptidyl-prolyl cis-trans isomerase FKBP3
Search

FKBP3

0.54	Peptidyl-prolyl cis-trans isomerase FKBP3

0.67	GO:0061077	chaperone-mediated protein folding
0.67	GO:0000413	protein peptidyl-prolyl isomerization

0.73	GO:0005528	FK506 binding
0.67	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.51	GO:0005515	protein binding
0.46	GO:0004872	receptor activity
0.43	GO:0003723	RNA binding

0.58	GO:0005634	nucleus
0.44	GO:0005737	cytoplasm

0.67

GO:0003755

sp|P26892|IL6_BOVIN
Interleukin-6
Search

IL6

0.94	Interleukin 6 (Interferon, beta 2)

0.75	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.61	GO:0043373	CD4-positive, alpha-beta T cell lineage commitment
0.61	GO:0006954	inflammatory response
0.58	GO:0002252	immune effector process
0.56	GO:0001781	neutrophil apoptotic process
0.56	GO:0071354	cellular response to interleukin-6
0.55	GO:0032966	negative regulation of collagen biosynthetic process
0.54	GO:0051024	positive regulation of immunoglobulin secretion
0.54	GO:0050871	positive regulation of B cell activation

0.86	GO:0005138	interleukin-6 receptor binding
0.80	GO:0005125	cytokine activity
0.59	GO:0008083	growth factor activity

0.66	GO:0005576	extracellular region
0.55	GO:0005896	interleukin-6 receptor complex
0.36	GO:0005788	endoplasmic reticulum lumen

sp|P26895|IL7_BOVIN
Interleukin-7
Search

IL7

0.97	Interleukin-7 variant 3

0.76	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.65	GO:0045453	bone resorption
0.64	GO:0030890	positive regulation of B cell proliferation
0.64	GO:0001961	positive regulation of cytokine-mediated signaling pathway
0.64	GO:0002360	T cell lineage commitment
0.63	GO:1901099	negative regulation of signal transduction in absence of ligand
0.63	GO:0045582	positive regulation of T cell differentiation
0.63	GO:0048873	homeostasis of number of cells within a tissue
0.63	GO:0032722	positive regulation of chemokine production

0.87	GO:0005139	interleukin-7 receptor binding
0.78	GO:0008083	growth factor activity
0.71	GO:0005125	cytokine activity

0.66	GO:0005576	extracellular region
0.30	GO:0016020	membrane

sp|P26917|SMS_BOVIN
Somatostatin
Search

SST

0.97	Preprosomatostatin I

0.76	GO:0010469	regulation of receptor activity
0.56	GO:0030334	regulation of cell migration
0.45	GO:0007267	cell-cell signaling
0.44	GO:0007166	cell surface receptor signaling pathway
0.40	GO:0010447	response to acidic pH
0.40	GO:0006972	hyperosmotic response
0.40	GO:0043200	response to amino acid
0.39	GO:0048545	response to steroid hormone
0.38	GO:0009408	response to heat
0.37	GO:0042493	response to drug

0.79	GO:0005179	hormone activity
0.34	GO:0031878	type 1 somatostatin receptor binding
0.32	GO:0003676	nucleic acid binding

0.66	GO:0005576	extracellular region
0.39	GO:0043025	neuronal cell body
0.30	GO:0016020	membrane

sp|P27117|DCOR_BOVIN
Ornithine decarboxylase
Search

ODC1

0.48	Ornithine decarboxylase

0.74	GO:0006596	polyamine biosynthetic process
0.57	GO:0009445	putrescine metabolic process
0.55	GO:0001822	kidney development
0.54	GO:0006591	ornithine metabolic process
0.54	GO:0042176	regulation of protein catabolic process
0.54	GO:0008284	positive regulation of cell proliferation
0.53	GO:0009615	response to virus
0.44	GO:0042462	eye photoreceptor cell development
0.35	GO:0006521	regulation of cellular amino acid metabolic process

0.60	GO:0004586	ornithine decarboxylase activity
0.53	GO:0042803	protein homodimerization activity

0.49	GO:0005829	cytosol
0.38	GO:0048471	perinuclear region of cytoplasm

0.60	EC:4.1.1.17	GO:0004586
0.60	KEGG:R00670	GO:0004586

sp|P27214|ANX11_BOVIN
Annexin A11
Search

ANXA11

0.58

Annexin

0.52	GO:0051592	response to calcium ion
0.52	GO:0006909	phagocytosis
0.49	GO:0032506	cytokinetic process
0.32	GO:0050819	negative regulation of coagulation

0.81	GO:0005544	calcium-dependent phospholipid binding
0.70	GO:0005509	calcium ion binding
0.55	GO:0008429	phosphatidylethanolamine binding
0.54	GO:0044548	S100 protein binding
0.53	GO:0048306	calcium-dependent protein binding
0.38	GO:0023026	MHC class II protein complex binding
0.34	GO:0003723	RNA binding

0.54	GO:0005766	primary lysosome
0.54	GO:0042581	specific granule
0.52	GO:0030496	midbody
0.52	GO:0045335	phagocytic vesicle
0.50	GO:0005819	spindle
0.49	GO:0005635	nuclear envelope
0.47	GO:0005654	nucleoplasm
0.46	GO:0005829	cytosol
0.39	GO:0042470	melanosome
0.37	GO:0070062	extracellular exosome

sp|P27424|MFAP2_BOVIN
Microfibrillar-associated protein 2
Search

MFAP2

0.97	Microfibril-associated glycoprotein 1

0.64	GO:0048048	embryonic eye morphogenesis
0.64	GO:0048050	post-embryonic eye morphogenesis
0.43	GO:0001568	blood vessel development
0.39	GO:0030097	hemopoiesis
0.39	GO:0036344	platelet morphogenesis
0.37	GO:0048646	anatomical structure formation involved in morphogenesis
0.36	GO:0030198	extracellular matrix organization
0.35	GO:0006812	cation transport
0.35	GO:0097435	supramolecular fiber organization
0.34	GO:0006099	tricarboxylic acid cycle

0.40	GO:0070051	fibrinogen binding
0.39	GO:0001968	fibronectin binding
0.35	GO:0016887	ATPase activity
0.35	GO:0051538	3 iron, 4 sulfur cluster binding
0.35	GO:0008177	succinate dehydrogenase (ubiquinone) activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0046872	metal ion binding
0.34	GO:0051537	2 iron, 2 sulfur cluster binding

0.86	GO:0001527	microfibril
0.40	GO:0005578	proteinaceous extracellular matrix
0.35	GO:0005615	extracellular space
0.33	GO:0031966	mitochondrial membrane
0.33	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.35	EC:3.6.1.3	GO:0016887
0.35	KEGG:R02164	GO:0008177

sp|P27479|LOX15_BOVIN
Arachidonate 15-lipoxygenase
Search

ALOX15

0.94	Arachidonate lipoxygenase, epidermal

0.67	GO:0019372	lipoxygenase pathway
0.65	GO:0019369	arachidonic acid metabolic process
0.62	GO:2001303	lipoxin A4 biosynthetic process
0.55	GO:0035963	cellular response to interleukin-13
0.54	GO:0030155	regulation of cell adhesion
0.53	GO:1901751	leukotriene A4 metabolic process
0.53	GO:2001304	lipoxin B4 metabolic process
0.53	GO:0043651	linoleic acid metabolic process
0.53	GO:0055114	oxidation-reduction process
0.52	GO:0010544	negative regulation of platelet activation

0.75	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.62	GO:0005506	iron ion binding
0.52	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.46	GO:0047977	hepoxilin-epoxide hydrolase activity
0.43	GO:0051120	hepoxilin A3 synthase activity
0.37	GO:0097260	eoxin A4 synthase activity
0.36	GO:0019870	potassium channel inhibitor activity
0.34	GO:0005515	protein binding
0.33	GO:0032041	NAD-dependent histone deacetylase activity (H3-K14 specific)

0.51	GO:0005829	cytosol
0.50	GO:0005811	lipid droplet
0.50	GO:0042383	sarcolemma
0.49	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.36	GO:0070062	extracellular exosome
0.32	GO:0005634	nucleus

0.75

EC:1.13.11

GO:0016702

sp|P27595|HXK1_BOVIN
Hexokinase-1
Search

HK1

0.37	Phosphotransferase

0.82	GO:0001678	cellular glucose homeostasis
0.74	GO:0046835	carbohydrate phosphorylation
0.71	GO:0006757	ATP generation from ADP
0.69	GO:0006090	pyruvate metabolic process
0.68	GO:0016052	carbohydrate catabolic process
0.67	GO:0019362	pyridine nucleotide metabolic process
0.51	GO:0072656	maintenance of protein location in mitochondrion
0.51	GO:0002741	positive regulation of cytokine secretion involved in immune response
0.50	GO:0050718	positive regulation of interleukin-1 beta secretion
0.47	GO:0072655	establishment of protein localization to mitochondrion

0.83	GO:0005536	glucose binding
0.79	GO:0004396	hexokinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0042834	peptidoglycan binding

0.50	GO:0097228	sperm principal piece
0.47	GO:0045121	membrane raft
0.43	GO:0005829	cytosol
0.41	GO:0005739	mitochondrion
0.30	GO:0098588	bounding membrane of organelle
0.30	GO:0031975	envelope
0.30	GO:0044446	intracellular organelle part
0.30	GO:0019867	outer membrane

0.79

EC:2.7.1.1

GO:0004396

sp|P27628|TUFT1_BOVIN
Tuftelin
Search

TUFT1

0.96

Tuftelin

0.50	GO:0031214	biomineral tissue development
0.41	GO:0042476	odontogenesis
0.40	GO:0001503	ossification
0.37	GO:0016197	endosomal transport
0.36	GO:0006886	intracellular protein transport
0.34	GO:0007165	signal transduction

0.42	GO:0030345	structural constituent of tooth enamel
0.41	GO:0005515	protein binding
0.37	GO:0032266	phosphatidylinositol-3-phosphate binding

0.48	GO:0005737	cytoplasm
0.43	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

sp|P27674|GTR1_BOVIN
Solute carrier family 2, facilitated glucose transporter member 1
Search

SLC2A1

0.84	Glucose transporter type 1

0.73	GO:1904659	glucose transmembrane transport
0.53	GO:0070837	dehydroascorbic acid transport
0.50	GO:0042149	cellular response to glucose starvation
0.50	GO:0071548	response to dexamethasone
0.50	GO:0032868	response to insulin
0.46	GO:0006461	protein complex assembly
0.41	GO:0002040	sprouting angiogenesis
0.39	GO:1904016	response to Thyroglobulin triiodothyronine
0.38	GO:0010827	regulation of glucose transport
0.38	GO:0071260	cellular response to mechanical stimulus

0.74	GO:0005355	glucose transmembrane transporter activity
0.53	GO:0033300	dehydroascorbic acid transmembrane transporter activity
0.53	GO:0043621	protein self-association
0.47	GO:0042802	identical protein binding
0.37	GO:0042910	xenobiotic transmembrane transporter activity
0.37	GO:0019900	kinase binding

0.52	GO:0001939	female pronucleus
0.51	GO:0030864	cortical actin cytoskeleton
0.50	GO:0030496	midbody
0.49	GO:0016323	basolateral plasma membrane
0.49	GO:0016324	apical plasma membrane
0.48	GO:0045121	membrane raft
0.46	GO:0031982	vesicle
0.45	GO:0005887	integral component of plasma membrane
0.44	GO:0005829	cytosol
0.38	GO:0014704	intercalated disc

sp|P27718|DDC_BOVIN
Aromatic-L-amino-acid decarboxylase
Search

DDC

0.74	Aromatic-L-amino-acid decarboxylase

0.60	GO:0006520	cellular amino acid metabolic process
0.47	GO:0009636	response to toxic substance
0.45	GO:0042416	dopamine biosynthetic process
0.43	GO:0033076	isoquinoline alkaloid metabolic process
0.42	GO:0007275	multicellular organism development
0.42	GO:0015842	aminergic neurotransmitter loading into synaptic vesicle
0.42	GO:0052314	phytoalexin metabolic process
0.42	GO:0060322	head development
0.41	GO:0042427	serotonin biosynthetic process
0.41	GO:0071312	cellular response to alkaloid

0.68	GO:0016831	carboxy-lyase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.49	GO:0019899	enzyme binding
0.39	GO:0019904	protein domain specific binding
0.39	GO:0016597	amino acid binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.40	GO:0008021	synaptic vesicle
0.40	GO:0043025	neuronal cell body
0.40	GO:0030424	axon
0.36	GO:0070062	extracellular exosome
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.68

EC:4.1.1

GO:0016831

sp|P27922|SC6A3_BOVIN
Sodium-dependent dopamine transporter
Search

SLC6A3

0.61	Solute carrier family 6 (neurotransmitter transporter), member 3

0.82	GO:0051937	catecholamine transport
0.76	GO:0006836	neurotransmitter transport
0.67	GO:0015696	ammonium transport
0.66	GO:0042420	dopamine catabolic process
0.66	GO:0060134	prepulse inhibition
0.66	GO:0042416	dopamine biosynthetic process
0.65	GO:0042053	regulation of dopamine metabolic process
0.65	GO:0021984	adenohypophysis development
0.65	GO:0007595	lactation
0.64	GO:0042220	response to cocaine

0.81	GO:0005330	dopamine:sodium symporter activity
0.65	GO:0035240	dopamine binding
0.63	GO:0047485	protein N-terminus binding
0.49	GO:0005333	norepinephrine transmembrane transporter activity
0.47	GO:0043014	alpha-tubulin binding
0.46	GO:0048487	beta-tubulin binding

0.66	GO:0016600	flotillin complex
0.64	GO:0043005	neuron projection
0.62	GO:0005887	integral component of plasma membrane
0.60	GO:0043025	neuronal cell body
0.60	GO:0009986	cell surface
0.58	GO:0098793	presynapse

sp|P27925|CREB1_BOVIN
Cyclic AMP-responsive element-binding protein 1
Search

CREB1

0.85	cAMP responsive element binding protein 1

0.64	GO:0060509	Type I pneumocyte differentiation
0.63	GO:0060430	lung saccule development
0.63	GO:0010944	negative regulation of transcription by competitive promoter binding
0.63	GO:0071294	cellular response to zinc ion
0.62	GO:0035729	cellular response to hepatocyte growth factor stimulus
0.62	GO:0033762	response to glucagon
0.61	GO:0045672	positive regulation of osteoclast differentiation
0.61	GO:0033363	secretory granule organization
0.61	GO:0021983	pituitary gland development
0.61	GO:0055025	positive regulation of cardiac muscle tissue development

0.61	GO:0003700	DNA binding transcription factor activity
0.60	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.60	GO:0035497	cAMP response element binding
0.60	GO:0001102	RNA polymerase II activating transcription factor binding
0.60	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.53	GO:0042802	identical protein binding
0.53	GO:0019899	enzyme binding
0.41	GO:0001225	RNA polymerase II transcription coactivator binding
0.40	GO:1990763	arrestin family protein binding
0.39	GO:0030544	Hsp70 protein binding

0.65	GO:1990589	ATF4-CREB1 transcription factor complex
0.60	GO:0005719	nuclear euchromatin
0.52	GO:0005654	nucleoplasm
0.38	GO:0030424	axon
0.37	GO:0005759	mitochondrial matrix

sp|P28053|MMP1_BOVIN
Interstitial collagenase
Search

MMP1

0.72	interstitial collagenase A

0.60	GO:0006508	proteolysis
0.54	GO:0030574	collagen catabolic process
0.54	GO:0032461	positive regulation of protein oligomerization
0.46	GO:0022617	extracellular matrix disassembly
0.45	GO:0009888	tissue development
0.45	GO:0009653	anatomical structure morphogenesis
0.45	GO:0007275	multicellular organism development
0.43	GO:0003416	endochondral bone growth
0.43	GO:0036075	replacement ossification
0.41	GO:0030154	cell differentiation

0.70	GO:0004222	metalloendopeptidase activity
0.63	GO:0008270	zinc ion binding
0.44	GO:0005518	collagen binding
0.41	GO:0004252	serine-type endopeptidase activity
0.40	GO:0005509	calcium ion binding
0.34	GO:0001047	core promoter binding
0.33	GO:0043565	sequence-specific DNA binding

0.74	GO:0031012	extracellular matrix
0.42	GO:0005615	extracellular space
0.40	GO:0005581	collagen trimer
0.35	GO:1904724	tertiary granule lumen
0.35	GO:0035580	specific granule lumen
0.32	GO:0005634	nucleus
0.30	GO:0044425	membrane part

0.70

GO:0004222

sp|P28088|EDNRB_BOVIN
Endothelin B receptor
Search

EDNRB

0.97	Endothelin receptor type B

0.83	GO:0086100	endothelin receptor signaling pathway
0.82	GO:0048484	enteric nervous system development
0.80	GO:0042310	vasoconstriction
0.77	GO:0008217	regulation of blood pressure
0.61	GO:0035645	enteric smooth muscle cell differentiation
0.61	GO:0007497	posterior midgut development
0.60	GO:0014043	negative regulation of neuron maturation
0.59	GO:0050931	pigment cell differentiation
0.59	GO:0048246	macrophage chemotaxis
0.59	GO:0014821	phasic smooth muscle contraction

0.83	GO:0004962	endothelin receptor activity
0.57	GO:0017046	peptide hormone binding
0.41	GO:0031702	type 1 angiotensin receptor binding

0.43	GO:0005886	plasma membrane
0.39	GO:0098857	membrane microdomain
0.39	GO:0031965	nuclear membrane
0.30	GO:0016021	integral component of membrane

sp|P28190|AA1R_BOVIN
Adenosine receptor A1
Search

ADORA1

0.97	Adenosine receptor A1

0.85	GO:0001973	adenosine receptor signaling pathway
0.61	GO:0070256	negative regulation of mucus secretion
0.61	GO:1900453	negative regulation of long term synaptic depression
0.60	GO:0003093	regulation of glomerular filtration
0.59	GO:0051930	regulation of sensory perception of pain
0.58	GO:0002686	negative regulation of leukocyte migration
0.56	GO:0050728	negative regulation of inflammatory response
0.54	GO:0060079	excitatory postsynaptic potential
0.43	GO:0008285	negative regulation of cell proliferation
0.42	GO:0032088	negative regulation of NF-kappaB transcription factor activity

0.85	GO:0001609	G-protein coupled adenosine receptor activity
0.40	GO:0032795	heterotrimeric G-protein binding
0.38	GO:0031683	G-protein beta/gamma-subunit complex binding
0.38	GO:0001664	G-protein coupled receptor binding
0.38	GO:0004629	phospholipase C activity
0.37	GO:0031072	heat shock protein binding
0.37	GO:0046982	protein heterodimerization activity
0.36	GO:0001883	purine nucleoside binding

0.56	GO:0043197	dendritic spine
0.55	GO:0005886	plasma membrane
0.38	GO:0043195	terminal bouton
0.38	GO:0044304	main axon
0.38	GO:0014069	postsynaptic density
0.38	GO:0048786	presynaptic active zone
0.38	GO:0043025	neuronal cell body
0.38	GO:0031252	cell leading edge
0.36	GO:0005783	endoplasmic reticulum
0.34	GO:0042629	mast cell granule

sp|P28291|CCL2_BOVIN
C-C motif chemokine 2
Search

0.75	C-C motif chemokine

0.82	GO:0060326	cell chemotaxis
0.74	GO:0006955	immune response
0.73	GO:0010469	regulation of receptor activity
0.64	GO:0097529	myeloid leukocyte migration
0.60	GO:0071674	mononuclear cell migration
0.60	GO:2000501	regulation of natural killer cell chemotaxis
0.59	GO:0071347	cellular response to interleukin-1
0.58	GO:0071356	cellular response to tumor necrosis factor
0.57	GO:0006954	inflammatory response
0.56	GO:0019221	cytokine-mediated signaling pathway

0.84	GO:0008009	chemokine activity
0.59	GO:0048020	CCR chemokine receptor binding
0.47	GO:0016004	phospholipase activator activity
0.40	GO:0008201	heparin binding
0.40	GO:0004672	protein kinase activity
0.37	GO:0046983	protein dimerization activity
0.35	GO:0005153	interleukin-8 receptor binding

0.71	GO:0005615	extracellular space
0.36	GO:0005622	intracellular

sp|P28327|RK_BOVIN
Rhodopsin kinase
Search

GRK1

0.69	G protein-coupled receptor kinase

0.76	GO:0022400	regulation of rhodopsin mediated signaling pathway
0.66	GO:0007601	visual perception
0.63	GO:0006468	protein phosphorylation
0.60	GO:0007165	signal transduction
0.43	GO:0048601	oocyte morphogenesis
0.43	GO:0009886	post-embryonic animal morphogenesis
0.43	GO:0003384	apical constriction involved in gastrulation
0.42	GO:0008592	regulation of Toll signaling pathway
0.42	GO:0043950	positive regulation of cAMP-mediated signaling
0.42	GO:0002805	regulation of antimicrobial peptide biosynthetic process

0.85	GO:0004703	G-protein coupled receptor kinase activity
0.79	GO:0050254	rhodopsin kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding

0.40	GO:0001750	photoreceptor outer segment
0.38	GO:0060170	ciliary membrane
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.85

GO:0004703

sp|P28339|DPOD1_BOVIN
DNA polymerase delta catalytic subunit
Search

POLD1

0.48	DNA polymerase delta catalytic subunit

0.67	GO:0071897	DNA biosynthetic process
0.65	GO:0006260	DNA replication
0.63	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.57	GO:0006287	base-excision repair, gap-filling
0.50	GO:0006297	nucleotide-excision repair, DNA gap filling
0.42	GO:0055089	fatty acid homeostasis
0.41	GO:0034644	cellular response to UV
0.36	GO:0042769	DNA damage response, detection of DNA damage
0.35	GO:0006301	postreplication repair
0.35	GO:0006283	transcription-coupled nucleotide-excision repair

0.72	GO:0008408	3'-5' exonuclease activity
0.71	GO:0003887	DNA-directed DNA polymerase activity
0.64	GO:0051539	4 iron, 4 sulfur cluster binding
0.55	GO:0003677	DNA binding
0.52	GO:1901265	nucleoside phosphate binding
0.52	GO:0046872	metal ion binding
0.51	GO:0036094	small molecule binding
0.45	GO:0019899	enzyme binding
0.45	GO:0016895	exodeoxyribonuclease activity, producing 5'-phosphomonoesters
0.40	GO:0003682	chromatin binding

0.59	GO:0005634	nucleus
0.51	GO:0016235	aggresome
0.47	GO:0031974	membrane-enclosed lumen
0.45	GO:0030894	replisome
0.45	GO:0042575	DNA polymerase complex
0.45	GO:0005829	cytosol
0.38	GO:0000781	chromosome, telomeric region
0.37	GO:1990391	DNA repair complex
0.35	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.71

GO:0003887

sp|P28782|S10A8_BOVIN
Protein S100-A8
Search

S100A8

0.97	S100 calcium binding protein A8

0.81	GO:0050727	regulation of inflammatory response
0.79	GO:0070488	neutrophil aggregation
0.79	GO:0045087	innate immune response
0.77	GO:0018119	peptidyl-cysteine S-nitrosylation
0.76	GO:0002523	leukocyte migration involved in inflammatory response
0.73	GO:0030593	neutrophil chemotaxis
0.73	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway
0.72	GO:0014002	astrocyte development
0.72	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.68	GO:0032103	positive regulation of response to external stimulus

0.87	GO:0035662	Toll-like receptor 4 binding
0.87	GO:0050544	arachidonic acid binding
0.86	GO:0050786	RAGE receptor binding
0.74	GO:0008017	microtubule binding
0.70	GO:0005509	calcium ion binding
0.63	GO:0008270	zinc ion binding
0.37	GO:0048306	calcium-dependent protein binding

0.67	GO:0045111	intermediate filament cytoskeleton
0.62	GO:0005615	extracellular space
0.59	GO:0005829	cytosol

sp|P28783|S10A9_BOVIN
Protein S100-A9
Search

S100A9

0.97	Calcium-binding protein A9

0.65	GO:0050727	regulation of inflammatory response
0.64	GO:0045087	innate immune response
0.60	GO:0070488	neutrophil aggregation
0.58	GO:0002523	leukocyte migration involved in inflammatory response
0.58	GO:0035606	peptidyl-cysteine S-trans-nitrosylation
0.57	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.56	GO:0030593	neutrophil chemotaxis
0.56	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway
0.55	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.53	GO:0032103	positive regulation of response to external stimulus

0.72	GO:0050786	RAGE receptor binding
0.72	GO:0035662	Toll-like receptor 4 binding
0.72	GO:0050544	arachidonic acid binding
0.60	GO:0008017	microtubule binding
0.60	GO:0005509	calcium ion binding
0.53	GO:0008270	zinc ion binding
0.49	GO:0008324	cation transmembrane transporter activity
0.38	GO:0016209	antioxidant activity
0.38	GO:0015318	inorganic molecular entity transmembrane transporter activity
0.36	GO:0019855	calcium channel inhibitor activity

0.49	GO:0030054	cell junction
0.48	GO:0005615	extracellular space
0.47	GO:0005654	nucleoplasm
0.46	GO:0005829	cytosol
0.39	GO:0012505	endomembrane system
0.39	GO:0005856	cytoskeleton
0.38	GO:0005886	plasma membrane
0.36	GO:0060205	cytoplasmic vesicle lumen
0.35	GO:1903561	extracellular vesicle
0.35	GO:0099503	secretory vesicle

0.35	EC:4.99.1.1	GO:0004325
0.35	KEGG:R00310	GO:0004325

sp|P28800|A2AP_BOVIN
Alpha-2-antiplasmin
Search

SERPINF2

0.97	Alpha-2-plasmin inhibitor

0.85	GO:0051918	negative regulation of fibrinolysis
0.72	GO:0010951	negative regulation of endopeptidase activity
0.65	GO:0010757	negative regulation of plasminogen activation
0.65	GO:0003072	renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure
0.64	GO:0071636	positive regulation of transforming growth factor beta production
0.64	GO:0010714	positive regulation of collagen metabolic process
0.63	GO:0032965	regulation of collagen biosynthetic process
0.62	GO:0051496	positive regulation of stress fiber assembly
0.62	GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin
0.61	GO:0048661	positive regulation of smooth muscle cell proliferation

0.75	GO:0004867	serine-type endopeptidase inhibitor activity
0.61	GO:0002020	protease binding
0.56	GO:0042803	protein homodimerization activity
0.34	GO:0008233	peptidase activity
0.32	GO:0101005	ubiquitinyl hydrolase activity

0.73	GO:0005615	extracellular space
0.56	GO:0009986	cell surface
0.47	GO:0043234	protein complex
0.39	GO:1903561	extracellular vesicle
0.37	GO:0031093	platelet alpha granule lumen
0.30	GO:0016020	membrane

0.34

GO:0008233

sp|P28801|GSTP1_BOVIN
Glutathione S-transferase P
Search

GSTP1

0.68	Glutathione S-transferase pi

0.56	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process
0.56	GO:0071638	negative regulation of monocyte chemotactic protein-1 production
0.55	GO:0043508	negative regulation of JUN kinase activity
0.55	GO:0032691	negative regulation of interleukin-1 beta production
0.55	GO:0043651	linoleic acid metabolic process
0.54	GO:0032720	negative regulation of tumor necrosis factor production
0.53	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.53	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway
0.51	GO:0071466	cellular response to xenobiotic stimulus
0.50	GO:0006749	glutathione metabolic process

0.78	GO:0004364	glutathione transferase activity
0.58	GO:0035730	S-nitrosoglutathione binding
0.52	GO:0035731	dinitrosyl-iron complex binding
0.51	GO:0004602	glutathione peroxidase activity
0.39	GO:0008432	JUN kinase binding
0.39	GO:0043295	glutathione binding
0.38	GO:0019207	kinase regulator activity
0.36	GO:0070026	nitric oxide binding
0.34	GO:0008144	drug binding
0.34	GO:0010181	FMN binding

0.57	GO:0097057	TRAF2-GSTP1 complex
0.47	GO:0005829	cytosol
0.45	GO:0005739	mitochondrion
0.42	GO:0098788	dendritic knob
0.41	GO:0071683	sensory dendrite
0.40	GO:0005634	nucleus
0.39	GO:0097014	ciliary plasm
0.39	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0070062	extracellular exosome
0.36	GO:1904813	ficolin-1-rich granule lumen

0.78

EC:2.5.1.18

GO:0004364

sp|P29104|HPCL4_BOVIN
Hippocalcin-like protein 4
Search

HPCAL4

0.97	Hippocalcin like 4

0.54	GO:0065009	regulation of molecular function
0.50	GO:0007165	signal transduction
0.47	GO:0046676	negative regulation of insulin secretion
0.47	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus
0.46	GO:0045921	positive regulation of exocytosis
0.34	GO:0007417	central nervous system development

0.70	GO:0005509	calcium ion binding
0.66	GO:0005246	calcium channel regulator activity
0.38	GO:0008022	protein C-terminus binding
0.37	GO:0019904	protein domain specific binding

0.42	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|P29105|HPCL1_BOVIN
Hippocalcin-like protein 1
Search

HPCAL1

0.87	Hippocalcin-like protein 1

0.70	GO:0005509	calcium ion binding
0.36	GO:0005515	protein binding

0.38	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

sp|P29172|TAU_BOVIN
Microtubule-associated protein tau
Search

MAPT

0.77	Microtubule-associated protein tau

0.65	GO:1905689	positive regulation of diacylglycerol kinase activity
0.63	GO:0031175	neuron projection development
0.62	GO:0090258	negative regulation of mitochondrial fission
0.61	GO:1902474	positive regulation of protein localization to synapse
0.61	GO:0000226	microtubule cytoskeleton organization
0.61	GO:0042750	hibernation
0.61	GO:0010917	negative regulation of mitochondrial membrane potential
0.61	GO:1903748	negative regulation of establishment of protein localization to mitochondrion
0.60	GO:1990000	amyloid fibril formation
0.60	GO:0032930	positive regulation of superoxide anion generation

0.74	GO:0008017	microtubule binding
0.60	GO:0034185	apolipoprotein binding
0.59	GO:0071813	lipoprotein particle binding
0.55	GO:0017124	SH3 domain binding
0.54	GO:0019901	protein kinase binding
0.53	GO:0048018	receptor ligand activity
0.52	GO:0042803	protein homodimerization activity
0.42	GO:0003677	DNA binding

0.80	GO:0030424	axon
0.73	GO:0005874	microtubule
0.69	GO:0005829	cytosol
0.61	GO:0005875	microtubule associated complex
0.61	GO:0097418	neurofibrillary tangle
0.60	GO:0045298	tubulin complex
0.58	GO:0032589	neuron projection membrane
0.57	GO:0030426	growth cone
0.57	GO:0014069	postsynaptic density
0.56	GO:0005930	axoneme

sp|P29177|MGMT_BOVIN
Methylated-DNA--protein-cysteine methyltransferase (Fragment)
Search

0.10	Methylated-DNA--protein-cysteine methyltransferase (Fragment)

0.30	GO:0006974	cellular response to DNA damage stimulus
0.30	GO:0006807	nitrogen compound metabolic process
0.30	GO:0032259	methylation
0.30	GO:0046483	heterocycle metabolic process
0.30	GO:0044260	cellular macromolecule metabolic process
0.30	GO:1901360	organic cyclic compound metabolic process
0.30	GO:0044238	primary metabolic process
0.30	GO:0006725	cellular aromatic compound metabolic process

0.30	GO:0097159	organic cyclic compound binding
0.30	GO:0043167	ion binding
0.30	GO:0008168	methyltransferase activity
0.30	GO:1901363	heterocyclic compound binding

0.30

GO:0005634

nucleus

0.30

GO:0008168

sp|P29392|SPAD1_BOVIN
Spermadhesin-1
Search

0.97	Major seminal plasma glycoprotein PSP-II

0.82	GO:0007338	single fertilization
0.43	GO:0010469	regulation of receptor activity
0.35	GO:0006898	receptor-mediated endocytosis

0.44	GO:0008083	growth factor activity
0.43	GO:0008201	heparin binding
0.37	GO:0005044	scavenger receptor activity
0.35	GO:0005509	calcium ion binding

0.46	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

sp|P29473|NOS3_BOVIN
Nitric oxide synthase, endothelial
Search

NOS3

0.71	Nitric oxide synthase

0.84	GO:0006809	nitric oxide biosynthetic process
0.61	GO:0043267	negative regulation of potassium ion transport
0.61	GO:0002026	regulation of the force of heart contraction
0.60	GO:0031284	positive regulation of guanylate cyclase activity
0.60	GO:0014900	muscle hyperplasia
0.60	GO:0014740	negative regulation of muscle hyperplasia
0.60	GO:0014805	smooth muscle adaptation
0.59	GO:0051926	negative regulation of calcium ion transport
0.59	GO:0002028	regulation of sodium ion transport
0.59	GO:0050880	regulation of blood vessel size

0.85	GO:0004517	nitric-oxide synthase activity
0.77	GO:0005516	calmodulin binding
0.70	GO:0010181	FMN binding
0.68	GO:0050661	NADP binding
0.65	GO:0050660	flavin adenine dinucleotide binding
0.62	GO:0020037	heme binding
0.62	GO:0005506	iron ion binding
0.59	GO:0034617	tetrahydrobiopterin binding
0.57	GO:0097110	scaffold protein binding
0.55	GO:0003785	actin monomer binding

0.59	GO:0005901	caveola
0.47	GO:0005634	nucleus
0.46	GO:0042383	sarcolemma
0.45	GO:0033017	sarcoplasmic reticulum membrane
0.44	GO:0030018	Z disc
0.44	GO:0005856	cytoskeleton
0.43	GO:0045202	synapse
0.41	GO:0070013	intracellular organelle lumen
0.40	GO:0005794	Golgi apparatus
0.39	GO:0005739	mitochondrion

0.85

EC:1.14.13.39

GO:0004517

sp|P29702|FNTA_BOVIN
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
Search

FNTA

0.89	Hook microtubule-tethering protein 3

0.82	GO:0097354	prenylation
0.60	GO:0036211	protein modification process
0.59	GO:0090044	positive regulation of tubulin deacetylation
0.57	GO:0090045	positive regulation of deacetylase activity
0.56	GO:0044267	cellular protein metabolic process
0.55	GO:0045213	neurotransmitter receptor metabolic process
0.54	GO:0071340	skeletal muscle acetylcholine-gated channel clustering
0.53	GO:0099601	regulation of neurotransmitter receptor activity
0.38	GO:0022027	interkinetic nuclear migration
0.37	GO:0051645	Golgi localization

0.83	GO:0008318	protein prenyltransferase activity
0.55	GO:0043014	alpha-tubulin binding
0.53	GO:0030548	acetylcholine receptor regulator activity
0.52	GO:0030971	receptor tyrosine kinase binding
0.50	GO:0008017	microtubule binding
0.36	GO:0042802	identical protein binding
0.35	GO:0019840	isoprenoid binding
0.35	GO:0042277	peptide binding
0.33	GO:0008270	zinc ion binding
0.33	GO:0008144	drug binding

0.60	GO:0005953	CAAX-protein geranylgeranyltransferase complex
0.57	GO:0005965	protein farnesyltransferase complex
0.50	GO:0005875	microtubule associated complex
0.40	GO:0005886	plasma membrane
0.38	GO:0070695	FHF complex
0.37	GO:0000242	pericentriolar material
0.37	GO:0034451	centriolar satellite
0.37	GO:0030897	HOPS complex
0.37	GO:0005801	cis-Golgi network
0.36	GO:0005829	cytosol

0.83

EC:2.5.1

GO:0008318

sp|P30122|CEL_BOVIN
Bile salt-activated lipase (Fragment)
Search

CEL

0.44	Carboxylic ester hydrolase

0.62	GO:0006629	lipid metabolic process
0.44	GO:1901565	organonitrogen compound catabolic process
0.43	GO:0044248	cellular catabolic process
0.42	GO:0043603	cellular amide metabolic process
0.36	GO:0030299	intestinal cholesterol absorption
0.35	GO:0006775	fat-soluble vitamin metabolic process
0.35	GO:0016049	cell growth
0.34	GO:1902652	secondary alcohol metabolic process
0.34	GO:0046164	alcohol catabolic process
0.34	GO:0030154	cell differentiation

0.61	GO:0016788	hydrolase activity, acting on ester bonds
0.33	GO:0005515	protein binding

0.34	GO:0005794	Golgi apparatus
0.34	GO:0005783	endoplasmic reticulum
0.30	GO:0016020	membrane

0.61

EC:3.1

GO:0016788

sp|P30205|WC11_BOVIN
Antigen WC1.1
Search

0.72

GO:0006898

receptor-mediated endocytosis

0.81	GO:0005044	scavenger receptor activity
0.33	GO:0030246	carbohydrate binding

0.36	GO:0009897	external side of plasma membrane
0.30	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

sp|P30274|CCNA2_BOVIN
Cyclin-A2
Search

0.62

Cyclin A

0.59	GO:0000086	G2/M transition of mitotic cell cycle
0.58	GO:0016572	histone phosphorylation
0.58	GO:0044843	cell cycle G1/S phase transition
0.56	GO:0007265	Ras protein signal transduction
0.52	GO:0045893	positive regulation of transcription, DNA-templated
0.52	GO:0051726	regulation of cell cycle
0.44	GO:0007423	sensory organ development
0.42	GO:0071373	cellular response to luteinizing hormone stimulus
0.42	GO:0071314	cellular response to cocaine
0.42	GO:1990314	cellular response to insulin-like growth factor stimulus

0.58	GO:0097472	cyclin-dependent protein kinase activity
0.54	GO:0019901	protein kinase binding
0.54	GO:0019904	protein domain specific binding
0.36	GO:0001103	RNA polymerase II repressing transcription factor binding

0.62	GO:0097124	cyclin A2-CDK2 complex
0.61	GO:0001940	male pronucleus
0.61	GO:0001939	female pronucleus
0.51	GO:0005654	nucleoplasm
0.49	GO:0005829	cytosol
0.41	GO:0097123	cyclin A1-CDK2 complex
0.39	GO:0015630	microtubule cytoskeleton
0.35	GO:0001750	photoreceptor outer segment
0.35	GO:0034464	BBSome
0.35	GO:0005930	axoneme

sp|P30367|IL4_BOVIN
Interleukin-4
Search

IL4

0.96	Interleukin-4 (Predicted)

0.75	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.73	GO:0042113	B cell activation
0.53	GO:1903660	negative regulation of complement-dependent cytotoxicity
0.51	GO:0032736	positive regulation of interleukin-13 production
0.51	GO:0043011	myeloid dendritic cell differentiation
0.50	GO:2000352	negative regulation of endothelial cell apoptotic process
0.50	GO:1902105	regulation of leukocyte differentiation
0.50	GO:0010633	negative regulation of epithelial cell migration
0.49	GO:0002440	production of molecular mediator of immune response

0.86	GO:0005136	interleukin-4 receptor binding
0.78	GO:0008083	growth factor activity
0.70	GO:0005125	cytokine activity

0.66

GO:0005576

extracellular region

sp|P30404|PPIF_BOVIN
Peptidyl-prolyl cis-trans isomerase F, mitochondrial
Search

PPIF

0.49	Peptidyl-prolyl cis-trans isomerase

0.72	GO:0000413	protein peptidyl-prolyl isomerization
0.68	GO:0006457	protein folding
0.57	GO:0010849	regulation of proton-transporting ATPase activity, rotational mechanism
0.57	GO:2000276	negative regulation of oxidative phosphorylation uncoupler activity
0.56	GO:0090201	negative regulation of release of cytochrome c from mitochondria
0.56	GO:1902445	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death
0.56	GO:1902686	mitochondrial outer membrane permeabilization involved in programmed cell death
0.56	GO:0090324	negative regulation of oxidative phosphorylation
0.55	GO:0070301	cellular response to hydrogen peroxide
0.55	GO:0071243	cellular response to arsenic-containing substance

0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.41	GO:0016018	cyclosporin A binding
0.35	GO:0005515	protein binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003723	RNA binding
0.32	GO:0016301	kinase activity

0.57	GO:0005757	mitochondrial permeability transition pore complex
0.42	GO:0005759	mitochondrial matrix
0.38	GO:0005753	mitochondrial proton-transporting ATP synthase complex
0.34	GO:0009533	chloroplast stromal thylakoid
0.33	GO:0031977	thylakoid lumen
0.33	GO:0005750	mitochondrial respiratory chain complex III
0.33	GO:0009535	chloroplast thylakoid membrane

0.72

GO:0003755

sp|P30535|TSPO_BOVIN
Translocator protein
Search

TSPO

0.90	Peripheral benzodiazepine receptor

0.59	GO:0072656	maintenance of protein location in mitochondrion
0.58	GO:1903147	negative regulation of autophagy of mitochondrion
0.58	GO:1903578	regulation of ATP metabolic process
0.56	GO:1900543	negative regulation of purine nucleotide metabolic process
0.56	GO:0031397	negative regulation of protein ubiquitination
0.56	GO:2000379	positive regulation of reactive oxygen species metabolic process
0.53	GO:0072655	establishment of protein localization to mitochondrion
0.44	GO:0060319	primitive erythrocyte differentiation
0.42	GO:0007568	aging
0.41	GO:0043065	positive regulation of apoptotic process

0.56	GO:0044325	ion channel binding
0.41	GO:0008503	benzodiazepine receptor activity
0.39	GO:0005497	androgen binding
0.39	GO:0015485	cholesterol binding
0.35	GO:0017127	cholesterol transporter activity

0.46	GO:0005739	mitochondrion
0.41	GO:0031968	organelle outer membrane
0.36	GO:0070062	extracellular exosome
0.36	GO:0005783	endoplasmic reticulum
0.30	GO:0016021	integral component of membrane

sp|P30546|HRH1_BOVIN
Histamine H1 receptor
Search

HRH1

0.97	Histamine H1 receptor

0.85	GO:0048245	eosinophil chemotaxis
0.85	GO:0043114	regulation of vascular permeability
0.85	GO:0045907	positive regulation of vasoconstriction
0.69	GO:0007186	G-protein coupled receptor signaling pathway
0.61	GO:0050804	modulation of chemical synaptic transmission
0.60	GO:0008542	visual learning
0.59	GO:0007613	memory
0.49	GO:0071420	cellular response to histamine
0.49	GO:0006954	inflammatory response
0.39	GO:0032962	positive regulation of inositol trisphosphate biosynthetic process

0.85	GO:0004969	histamine receptor activity
0.37	GO:0015085	calcium ion transmembrane transporter activity
0.37	GO:0051381	histamine binding
0.35	GO:0016907	G-protein coupled acetylcholine receptor activity

0.52	GO:0005829	cytosol
0.45	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P30671|GBG7_BOVIN
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7
Search

GNG7

0.70	Guanine nucleotide-binding protein subunit gamma

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.37	GO:0007168	receptor guanylyl cyclase signaling pathway
0.37	GO:0071377	cellular response to glucagon stimulus
0.36	GO:0001662	behavioral fear response
0.36	GO:0045761	regulation of adenylate cyclase activity
0.36	GO:0007626	locomotory behavior
0.36	GO:0021987	cerebral cortex development
0.35	GO:0032496	response to lipopolysaccharide
0.34	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.34	GO:0006915	apoptotic process

0.64	GO:0004871	signal transducer activity
0.49	GO:0030165	PDZ domain binding
0.35	GO:0042301	phosphate ion binding
0.34	GO:0051015	actin filament binding
0.34	GO:0008017	microtubule binding
0.32	GO:0016787	hydrolase activity

0.81	GO:1905360	GTPase complex
0.80	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.66	GO:0098797	plasma membrane protein complex
0.37	GO:0070062	extracellular exosome
0.35	GO:0099513	polymeric cytoskeletal fiber
0.35	GO:0015629	actin cytoskeleton
0.33	GO:0015630	microtubule cytoskeleton

0.32

GO:0016787

sp|P30907|AL3A1_BOVIN
Aldehyde dehydrogenase, dimeric NADP-preferring (Fragment)
Search

0.71	Aldehyde dehydrogenase, dimeric NADP-preferring

0.65	GO:0006081	cellular aldehyde metabolic process
0.52	GO:0055114	oxidation-reduction process
0.48	GO:0033306	phytol metabolic process
0.45	GO:0007422	peripheral nervous system development
0.45	GO:0008544	epidermis development
0.44	GO:0007417	central nervous system development
0.37	GO:0051591	response to cAMP
0.37	GO:0051384	response to glucocorticoid
0.36	GO:0001666	response to hypoxia
0.36	GO:0007584	response to nutrient

0.75	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity
0.54	GO:0004029	aldehyde dehydrogenase (NAD) activity
0.52	GO:0008106	alcohol dehydrogenase (NADP+) activity
0.46	GO:0046577	long-chain-alcohol oxidase activity
0.46	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity
0.33	GO:0005515	protein binding

0.49	GO:0005783	endoplasmic reticulum
0.46	GO:0005829	cytosol
0.40	GO:0005886	plasma membrane
0.38	GO:0031090	organelle membrane
0.38	GO:0005740	mitochondrial envelope
0.36	GO:0005615	extracellular space
0.36	GO:0042579	microbody
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0031984	organelle subcompartment
0.34	GO:1903561	extracellular vesicle

0.75

EC:1.2.1.5

GO:0004030

sp|P30922|CH3L1_BOVIN
Chitinase-3-like protein 1
Search

CHI3L1

0.47	Acidic mammalian chitinase

0.67	GO:0045766	positive regulation of angiogenesis
0.64	GO:0006030	chitin metabolic process
0.62	GO:0072606	interleukin-8 secretion
0.60	GO:0005975	carbohydrate metabolic process
0.60	GO:0010800	positive regulation of peptidyl-threonine phosphorylation
0.60	GO:0070741	response to interleukin-6
0.60	GO:0007250	activation of NF-kappaB-inducing kinase activity
0.59	GO:0051897	positive regulation of protein kinase B signaling
0.58	GO:0070555	response to interleukin-1
0.58	GO:0034612	response to tumor necrosis factor

0.77	GO:0008061	chitin binding
0.57	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.41	GO:0030246	carbohydrate binding
0.35	GO:0005201	extracellular matrix structural constituent
0.35	GO:0019900	kinase binding

0.64	GO:0005576	extracellular region
0.51	GO:0005783	endoplasmic reticulum
0.43	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0031982	vesicle
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.57

EC:3.2.1

GO:0004553

sp|P30931|TF_BOVIN
Tissue factor
Search

0.97	Coagulation factor III, tissue factor

0.82	GO:0007596	blood coagulation
0.79	GO:0002541	activation of plasma proteins involved in acute inflammatory response
0.77	GO:0010641	positive regulation of platelet-derived growth factor receptor signaling pathway
0.72	GO:0001938	positive regulation of endothelial cell proliferation
0.71	GO:0051897	positive regulation of protein kinase B signaling
0.71	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.70	GO:0045766	positive regulation of angiogenesis
0.50	GO:0019221	cytokine-mediated signaling pathway
0.40	GO:0002543	activation of blood coagulation via clotting cascade
0.39	GO:0050927	positive regulation of positive chemotaxis

0.67	GO:0002020	protease binding
0.64	GO:0005543	phospholipid binding
0.57	GO:0004252	serine-type endopeptidase activity
0.51	GO:0004896	cytokine receptor activity

0.73	GO:1905286	serine-type peptidase complex
0.64	GO:0009986	cell surface
0.63	GO:0031012	extracellular matrix
0.62	GO:0005615	extracellular space
0.41	GO:0005886	plasma membrane
0.38	GO:1903561	extracellular vesicle
0.37	GO:0098552	side of membrane
0.30	GO:0016021	integral component of membrane

0.57

GO:0004252

sp|P30932|CD9_BOVIN
CD9 antigen
Search

CD9

0.60	Tetraspanin

0.55	GO:0090331	negative regulation of platelet aggregation
0.54	GO:0030913	paranodal junction assembly
0.54	GO:0007342	fusion of sperm to egg plasma membrane involved in single fertilization
0.53	GO:0071404	cellular response to low-density lipoprotein particle stimulus
0.52	GO:0031623	receptor internalization
0.51	GO:0051271	negative regulation of cellular component movement
0.49	GO:0008285	negative regulation of cell proliferation
0.47	GO:0007155	cell adhesion
0.40	GO:0007166	cell surface receptor signaling pathway
0.38	GO:0048916	posterior lateral line development

0.51	GO:0070062	extracellular exosome
0.50	GO:0009897	external side of plasma membrane
0.39	GO:0005887	integral component of plasma membrane

sp|P31039|SDHA_BOVIN
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
Search

SDHA

0.68	Succinate dehydrogenase [ubiquinone] flavoprotein subunit A, mitochondrial

0.70	GO:0006099	tricarboxylic acid cycle
0.60	GO:0022900	electron transport chain
0.52	GO:0006105	succinate metabolic process
0.47	GO:0007399	nervous system development
0.44	GO:0009061	anaerobic respiration
0.40	GO:0006119	oxidative phosphorylation
0.36	GO:0006106	fumarate metabolic process
0.34	GO:0007034	vacuolar transport

0.78	GO:0008177	succinate dehydrogenase (ubiquinone) activity
0.65	GO:0050660	flavin adenine dinucleotide binding
0.40	GO:0009055	electron transfer activity
0.37	GO:0004333	fumarate hydratase activity
0.35	GO:0005515	protein binding

0.56	GO:0031966	mitochondrial membrane
0.56	GO:0019866	organelle inner membrane
0.49	GO:0045282	plasma membrane succinate dehydrogenase complex
0.49	GO:0043209	myelin sheath
0.49	GO:0045257	succinate dehydrogenase complex (ubiquinone)
0.49	GO:0045283	fumarate reductase complex
0.47	GO:0005730	nucleolus
0.44	GO:0098798	mitochondrial protein complex
0.36	GO:0045239	tricarboxylic acid cycle enzyme complex
0.30	GO:0031224	intrinsic component of membrane

0.78	EC:1.3.5.1	GO:0008177
0.78	KEGG:R02164	GO:0008177

sp|P31081|CH60_BOVIN
60 kDa heat shock protein, mitochondrial
Search

HSPD1

0.79	Heat shock protein, mitochondrial

0.76	GO:0042026	protein refolding
0.64	GO:0009409	response to cold
0.53	GO:0042110	T cell activation
0.52	GO:0002368	B cell cytokine production
0.52	GO:0048291	isotype switching to IgG isotypes
0.52	GO:0002842	positive regulation of T cell mediated immune response to tumor cell
0.52	GO:0001817	regulation of cytokine production
0.50	GO:0043032	positive regulation of macrophage activation
0.49	GO:0042100	B cell proliferation
0.49	GO:0045041	protein import into mitochondrial intermembrane space

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.51	GO:0034186	apolipoprotein A-I binding
0.51	GO:0008035	high-density lipoprotein particle binding
0.49	GO:0002039	p53 binding
0.49	GO:0044183	protein binding involved in protein folding
0.47	GO:0031625	ubiquitin protein ligase binding
0.46	GO:0051087	chaperone binding

0.50	GO:0005759	mitochondrial matrix
0.50	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex
0.49	GO:0046696	lipopolysaccharide receptor complex
0.48	GO:0043209	myelin sheath
0.48	GO:0030141	secretory granule
0.47	GO:0070062	extracellular exosome
0.47	GO:0005905	clathrin-coated pit
0.47	GO:0005769	early endosome
0.46	GO:0005829	cytosol
0.46	GO:0030135	coated vesicle

0.35

GO:0016787

sp|P31096|OSTP_BOVIN
Osteopontin
Search

SPP1

0.96	Secreted phosphoprotein 1

0.83	GO:0001503	ossification
0.72	GO:0007155	cell adhesion
0.63	GO:0006710	androgen catabolic process
0.63	GO:2000866	positive regulation of estradiol secretion
0.63	GO:0071394	cellular response to testosterone stimulus
0.61	GO:0033280	response to vitamin D
0.53	GO:0045893	positive regulation of transcription, DNA-templated
0.51	GO:0046852	positive regulation of bone remodeling
0.50	GO:0045124	regulation of bone resorption
0.49	GO:0032846	positive regulation of homeostatic process

0.48	GO:0050840	extracellular matrix binding
0.45	GO:0005125	cytokine activity
0.35	GO:0008201	heparin binding
0.33	GO:0016757	transferase activity, transferring glycosyl groups
0.33	GO:0005509	calcium ion binding
0.32	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity
0.32	GO:0003723	RNA binding

0.55	GO:0005615	extracellular space
0.53	GO:0005794	Golgi apparatus
0.38	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0031982	vesicle
0.37	GO:0043230	extracellular organelle
0.37	GO:0045177	apical part of cell
0.37	GO:0042995	cell projection
0.36	GO:0005788	endoplasmic reticulum lumen
0.33	GO:0031012	extracellular matrix
0.30	GO:0016020	membrane

0.33

GO:0016757

sp|P31098|OSTK_BOVIN
Osteopontin-K
Search

SPP1

0.96	Secreted phosphoprotein 1

0.83	GO:0001503	ossification
0.72	GO:0007155	cell adhesion
0.66	GO:0006710	androgen catabolic process
0.65	GO:2000866	positive regulation of estradiol secretion
0.65	GO:0071394	cellular response to testosterone stimulus
0.63	GO:0033280	response to vitamin D
0.54	GO:0045893	positive regulation of transcription, DNA-templated
0.52	GO:0046852	positive regulation of bone remodeling
0.52	GO:0045124	regulation of bone resorption
0.49	GO:0032846	positive regulation of homeostatic process

0.49	GO:0050840	extracellular matrix binding
0.45	GO:0005125	cytokine activity

0.57	GO:0005615	extracellular space
0.54	GO:0005794	Golgi apparatus
0.39	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0031982	vesicle
0.37	GO:0043230	extracellular organelle
0.37	GO:0045177	apical part of cell
0.37	GO:0042995	cell projection
0.36	GO:0005788	endoplasmic reticulum lumen

sp|P31228|OXDD_BOVIN
D-aspartate oxidase
Search

DDO

0.93	D-aspartate oxidase

0.76	GO:0046416	D-amino acid metabolic process
0.58	GO:0007625	grooming behavior
0.58	GO:0007320	insemination
0.55	GO:0006531	aspartate metabolic process
0.53	GO:0055114	oxidation-reduction process
0.52	GO:0042445	hormone metabolic process
0.49	GO:1901606	alpha-amino acid catabolic process
0.38	GO:0043649	dicarboxylic acid catabolic process
0.35	GO:0042416	dopamine biosynthetic process
0.35	GO:0055085	transmembrane transport

0.83	GO:0003884	D-amino-acid oxidase activity
0.73	GO:0071949	FAD binding
0.56	GO:0015922	aspartate oxidase activity
0.51	GO:0005102	receptor binding
0.34	GO:0022857	transmembrane transporter activity
0.33	GO:0046983	protein dimerization activity
0.32	GO:0046872	metal ion binding

0.48	GO:0005829	cytosol
0.39	GO:0005777	peroxisome
0.36	GO:0044438	microbody part
0.34	GO:0005741	mitochondrial outer membrane
0.34	GO:0031974	membrane-enclosed lumen
0.30	GO:0016021	integral component of membrane

0.83

EC:1.4.3.3

GO:0003884

sp|P31322|KAP3_BOVIN
cAMP-dependent protein kinase type II-beta regulatory subunit
Search

PRKAR2B

0.97	cAMP-dependent protein kinase type II-beta regulatory subunit

0.75	GO:0045859	regulation of protein kinase activity
0.56	GO:0033673	negative regulation of kinase activity
0.55	GO:0007612	learning
0.53	GO:0001933	negative regulation of protein phosphorylation
0.51	GO:0016310	phosphorylation
0.48	GO:0006631	fatty acid metabolic process
0.42	GO:0097338	response to clozapine
0.37	GO:0071377	cellular response to glucagon stimulus
0.37	GO:0003091	renal water homeostasis
0.36	GO:0007596	blood coagulation

0.85	GO:0008603	cAMP-dependent protein kinase regulator activity
0.84	GO:0030552	cAMP binding
0.61	GO:0034236	protein kinase A catalytic subunit binding
0.60	GO:0004862	cAMP-dependent protein kinase inhibitor activity
0.56	GO:0031625	ubiquitin protein ligase binding
0.53	GO:0016301	kinase activity
0.45	GO:0019904	protein domain specific binding
0.33	GO:0003735	structural constituent of ribosome

0.83	GO:0005952	cAMP-dependent protein kinase complex
0.57	GO:0097546	ciliary base
0.56	GO:0043198	dendritic shaft
0.55	GO:0043197	dendritic spine
0.55	GO:0005813	centrosome
0.46	GO:0098857	membrane microdomain
0.45	GO:0031588	nucleotide-activated protein kinase complex
0.44	GO:0005930	axoneme
0.44	GO:0005886	plasma membrane
0.39	GO:0043025	neuronal cell body

sp|P31404|VATA_BOVIN
V-type proton ATPase catalytic subunit A
Search

ATP6V1A

0.92	ATPase H+ transporting V1 subunit A

0.75	GO:0015991	ATP hydrolysis coupled proton transport
0.64	GO:0036295	cellular response to increased oxygen levels
0.62	GO:0046034	ATP metabolic process
0.57	GO:0006875	cellular metal ion homeostasis
0.56	GO:0055072	iron ion homeostasis
0.40	GO:0055078	sodium ion homeostasis
0.39	GO:0030004	cellular monovalent inorganic cation homeostasis
0.39	GO:0055074	calcium ion homeostasis
0.39	GO:0072503	cellular divalent inorganic cation homeostasis

0.80	GO:0046961	proton-transporting ATPase activity, rotational mechanism
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.80	GO:0033180	proton-transporting V-type ATPase, V1 domain
0.68	GO:0016324	apical plasma membrane
0.61	GO:0005902	microvillus
0.60	GO:0043209	myelin sheath
0.52	GO:0005829	cytosol
0.49	GO:0005765	lysosomal membrane
0.47	GO:0005739	mitochondrion
0.37	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

sp|P31407|VATB1_BOVIN
V-type proton ATPase subunit B, kidney isoform
Search

0.86	Vacuolar-type H+ transporting ATPase B2 subunit

0.74	GO:0015991	ATP hydrolysis coupled proton transport
0.64	GO:0007588	excretion
0.63	GO:0045851	pH reduction
0.62	GO:0042472	inner ear morphogenesis
0.61	GO:0001503	ossification
0.61	GO:0007605	sensory perception of sound
0.60	GO:0046034	ATP metabolic process
0.59	GO:0055074	calcium ion homeostasis
0.39	GO:0097401	synaptic vesicle lumen acidification

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0015078	hydrogen ion transmembrane transporter activity
0.38	GO:0032403	protein complex binding

0.78	GO:0033180	proton-transporting V-type ATPase, V1 domain
0.71	GO:0005902	microvillus
0.62	GO:0016328	lateral plasma membrane
0.61	GO:0016471	vacuolar proton-transporting V-type ATPase complex
0.61	GO:0016323	basolateral plasma membrane
0.60	GO:0016324	apical plasma membrane
0.58	GO:0005829	cytosol
0.54	GO:0001726	ruffle
0.54	GO:0043209	myelin sheath
0.43	GO:0098850	extrinsic component of synaptic vesicle membrane

sp|P31408|VATB2_BOVIN
V-type proton ATPase subunit B, brain isoform
Search

ATP6V1B2

0.95	V-type ATPase beta subunit

0.75	GO:0015991	ATP hydrolysis coupled proton transport
0.61	GO:0046034	ATP metabolic process
0.43	GO:0045851	pH reduction
0.42	GO:0007588	excretion
0.41	GO:0042472	inner ear morphogenesis
0.41	GO:0001503	ossification
0.41	GO:0007605	sensory perception of sound
0.40	GO:0055074	calcium ion homeostasis
0.37	GO:0051453	regulation of intracellular pH
0.37	GO:0033572	transferrin transport

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0015078	hydrogen ion transmembrane transporter activity
0.35	GO:0016787	hydrolase activity
0.34	GO:0005515	protein binding
0.33	GO:0022853	active ion transmembrane transporter activity
0.33	GO:0044877	macromolecular complex binding
0.33	GO:0015399	primary active transmembrane transporter activity

0.79	GO:0033180	proton-transporting V-type ATPase, V1 domain
0.54	GO:0005902	microvillus
0.50	GO:0001726	ruffle
0.50	GO:0043209	myelin sheath
0.47	GO:0005829	cytosol
0.42	GO:0043227	membrane-bounded organelle
0.41	GO:0005886	plasma membrane
0.41	GO:0043229	intracellular organelle
0.40	GO:0045177	apical part of cell
0.40	GO:0098805	whole membrane

0.35

GO:0016787

sp|P31717|NMT1_BOVIN
Glycylpeptide N-tetradecanoyltransferase 1
Search

NMT1

0.72	Glycylpeptide N-tetradecanoyltransferase

0.85	GO:0006499	N-terminal protein myristoylation
0.59	GO:0018201	peptidyl-glycine modification
0.51	GO:0001701	in utero embryonic development
0.48	GO:0042180	cellular ketone metabolic process
0.36	GO:1900739	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
0.35	GO:1901030	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
0.35	GO:0022400	regulation of rhodopsin mediated signaling pathway
0.35	GO:1903749	positive regulation of establishment of protein localization to mitochondrion
0.34	GO:0071901	negative regulation of protein serine/threonine kinase activity
0.34	GO:1905477	positive regulation of protein localization to membrane

0.85	GO:0004379	glycylpeptide N-tetradecanoyltransferase activity
0.35	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity
0.34	GO:0017069	snRNA binding
0.34	GO:0000062	fatty-acyl-CoA binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.51	GO:0019898	extrinsic component of membrane
0.49	GO:0005829	cytosol
0.42	GO:0005886	plasma membrane
0.37	GO:0005794	Golgi apparatus
0.33	GO:0005739	mitochondrion
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.85

EC:2.3.1.97

GO:0004379

sp|P31754|UMPS_BOVIN
Uridine 5'-monophosphate synthase
Search

UMPS

0.90	Uridine monophosphate synthetase

0.70	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process
0.69	GO:0044205	'de novo' UMP biosynthetic process
0.42	GO:0007595	lactation
0.41	GO:0007565	female pregnancy
0.40	GO:0035690	cellular response to drug
0.34	GO:0046686	response to cadmium ion
0.34	GO:0016036	cellular response to phosphate starvation

0.74	GO:0004588	orotate phosphoribosyltransferase activity
0.74	GO:0004590	orotidine-5'-phosphate decarboxylase activity
0.37	GO:0042802	identical protein binding

0.46	GO:0005634	nucleus
0.40	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.74	EC:2.4.2.10	GO:0004588
0.74	KEGG:R00965	GO:0004590

sp|P31783|CD8A_BOVIN
T-cell surface glycoprotein CD8 alpha chain
Search

CD8A

0.82	T-cell surface glycoprotein CD8 alpha chain

0.58	GO:0045065	cytotoxic T cell differentiation
0.54	GO:0002456	T cell mediated immunity
0.47	GO:0007166	cell surface receptor signaling pathway
0.41	GO:0050850	positive regulation of calcium-mediated signaling
0.39	GO:0051607	defense response to virus
0.36	GO:0019882	antigen processing and presentation
0.36	GO:0006954	inflammatory response
0.36	GO:0050776	regulation of immune response

0.38	GO:0042803	protein homodimerization activity
0.38	GO:0019901	protein kinase binding
0.38	GO:0042288	MHC class I protein binding
0.37	GO:0015026	coreceptor activity

0.62	GO:0009897	external side of plasma membrane
0.60	GO:0044853	plasma membrane raft
0.38	GO:0042101	T cell receptor complex
0.35	GO:0005887	integral component of plasma membrane
0.35	GO:0005576	extracellular region

sp|P31800|QCR1_BOVIN
Cytochrome b-c1 complex subunit 1, mitochondrial
Search

UQCRC1

0.90	Mitochondrial ubiquinol-cytochrome-c reductase complex core protein i

0.61	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c
0.49	GO:0016485	protein processing
0.44	GO:0009060	aerobic respiration

0.63	GO:0031625	ubiquitin protein ligase binding
0.54	GO:0046872	metal ion binding
0.47	GO:0004222	metalloendopeptidase activity
0.36	GO:0016681	oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor
0.34	GO:0009055	electron transfer activity

0.65	GO:0043209	myelin sheath
0.56	GO:0005829	cytosol
0.53	GO:0031966	mitochondrial membrane
0.53	GO:0019866	organelle inner membrane
0.49	GO:0098798	mitochondrial protein complex
0.48	GO:0045275	respiratory chain complex III
0.30	GO:0016021	integral component of membrane

0.47

GO:0004222

sp|P31836|NCAM1_BOVIN
Neural cell adhesion molecule 1
Search

NCAM1

0.91	Neural cell adhesion molecule 1

0.71	GO:0007155	cell adhesion
0.38	GO:0001928	regulation of exocyst assembly
0.37	GO:0031175	neuron projection development
0.37	GO:0050850	positive regulation of calcium-mediated signaling
0.36	GO:0007166	cell surface receptor signaling pathway
0.35	GO:0010288	response to lead ion
0.35	GO:0021794	thalamus development
0.35	GO:0051930	regulation of sensory perception of pain
0.35	GO:0060045	positive regulation of cardiac muscle cell proliferation
0.35	GO:0010033	response to organic substance

0.36	GO:0042802	identical protein binding
0.36	GO:0008201	heparin binding
0.35	GO:0030275	LRR domain binding
0.35	GO:0104005	hijacked molecular function
0.35	GO:0019899	enzyme binding
0.35	GO:0005104	fibroblast growth factor receptor binding
0.34	GO:0008092	cytoskeletal protein binding
0.34	GO:0098772	molecular function regulator

0.47	GO:0005829	cytosol
0.42	GO:0005886	plasma membrane
0.37	GO:0009986	cell surface
0.37	GO:0098552	side of membrane
0.37	GO:0030426	growth cone
0.37	GO:0031012	extracellular matrix
0.36	GO:0043209	myelin sheath
0.36	GO:0070062	extracellular exosome
0.36	GO:0043025	neuronal cell body
0.36	GO:0030424	axon

sp|P31976|EZRI_BOVIN
Ezrin
Search

EZR

0.97	Epididymis secretory protein Li 105

0.57	GO:0022614	membrane to membrane docking
0.56	GO:1902965	regulation of protein localization to early endosome
0.56	GO:2000643	positive regulation of early endosome to late endosome transport
0.56	GO:1905668	positive regulation of protein localization to endosome
0.55	GO:0061028	establishment of endothelial barrier
0.55	GO:0007159	leukocyte cell-cell adhesion
0.54	GO:0035088	establishment or maintenance of apical/basal cell polarity
0.53	GO:1900041	negative regulation of interleukin-2 secretion
0.53	GO:1902896	terminal web assembly
0.53	GO:0001951	intestinal D-glucose absorption

0.73	GO:0003779	actin binding
0.52	GO:0050839	cell adhesion molecule binding
0.52	GO:0034236	protein kinase A catalytic subunit binding
0.51	GO:0044548	S100 protein binding
0.51	GO:0034237	protein kinase A regulatory subunit binding
0.51	GO:0097718	disordered domain specific binding
0.51	GO:0051117	ATPase binding
0.50	GO:0008022	protein C-terminus binding
0.47	GO:0032403	protein complex binding
0.46	GO:0008017	microtubule binding

0.69	GO:0005856	cytoskeleton
0.56	GO:0071437	invadopodium
0.55	GO:0001931	uropod
0.54	GO:0005902	microvillus
0.53	GO:0030175	filopodium
0.53	GO:0098592	cytoplasmic side of apical plasma membrane
0.52	GO:0043209	myelin sheath
0.52	GO:0005925	focal adhesion
0.51	GO:0001772	immunological synapse
0.51	GO:0048471	perinuclear region of cytoplasm

0.34

EC:2.7.10.1

GO:0004714

sp|P32007|ADT3_BOVIN
ADP/ATP translocase 3
Search

0.80	Adenine nucleotide translocase

0.55	GO:0046902	regulation of mitochondrial membrane permeability
0.55	GO:0055085	transmembrane transport
0.54	GO:0015866	ADP transport
0.50	GO:0015867	ATP transport
0.50	GO:0043069	negative regulation of programmed cell death
0.47	GO:0060547	negative regulation of necrotic cell death
0.47	GO:0060544	regulation of necroptotic process
0.47	GO:0010823	negative regulation of mitochondrion organization
0.46	GO:0008637	apoptotic mitochondrial changes
0.45	GO:2001233	regulation of apoptotic signaling pathway

0.57	GO:0022857	transmembrane transporter activity
0.44	GO:0031625	ubiquitin protein ligase binding
0.34	GO:0047429	nucleoside-triphosphate diphosphatase activity
0.33	GO:0008171	O-methyltransferase activity
0.33	GO:0003723	RNA binding

0.62	GO:0005743	mitochondrial inner membrane
0.49	GO:0043209	myelin sheath
0.48	GO:0071817	MMXD complex
0.44	GO:0042645	mitochondrial nucleoid
0.38	GO:0098857	membrane microdomain
0.37	GO:0044455	mitochondrial membrane part
0.36	GO:0031301	integral component of organelle membrane
0.36	GO:0031012	extracellular matrix
0.35	GO:0005741	mitochondrial outer membrane
0.34	GO:0005634	nucleus

0.34

EC:3.6.1.19

GO:0047429

sp|P32120|ARRB2_BOVIN
Beta-arrestin-2
Search

ARRB2

0.97	Beta arrestin 2 variant 3

0.61	GO:0007165	signal transduction
0.54	GO:0043393	regulation of protein binding
0.53	GO:0002031	G-protein coupled receptor internalization
0.53	GO:0032226	positive regulation of synaptic transmission, dopaminergic
0.53	GO:0045953	negative regulation of natural killer cell mediated cytotoxicity
0.53	GO:0002092	positive regulation of receptor internalization
0.52	GO:0032691	negative regulation of interleukin-1 beta production
0.52	GO:0032695	negative regulation of interleukin-12 production
0.52	GO:2000727	positive regulation of cardiac muscle cell differentiation
0.52	GO:0034122	negative regulation of toll-like receptor signaling pathway

0.53	GO:0031701	angiotensin receptor binding
0.53	GO:0043422	protein kinase B binding
0.49	GO:0032947	protein complex scaffold activity
0.48	GO:0031625	ubiquitin protein ligase binding
0.42	GO:0031859	platelet activating factor receptor binding
0.41	GO:0031691	alpha-1A adrenergic receptor binding
0.41	GO:0031692	alpha-1B adrenergic receptor binding
0.41	GO:0031762	follicle-stimulating hormone receptor binding
0.41	GO:0031826	type 2A serotonin receptor binding
0.40	GO:0031748	D1 dopamine receptor binding

0.50	GO:0030139	endocytic vesicle
0.42	GO:0005634	nucleus
0.40	GO:0005886	plasma membrane
0.39	GO:0005905	clathrin-coated pit
0.39	GO:0043197	dendritic spine
0.39	GO:0014069	postsynaptic density
0.35	GO:0005829	cytosol

sp|P32236|GNRHR_BOVIN
Gonadotropin-releasing hormone receptor
Search

GNRHR

0.87	Pituitary gonadotropin releasing hormone receptor

0.77	GO:0097211	cellular response to gonadotropin-releasing hormone
0.69	GO:0007186	G-protein coupled receptor signaling pathway
0.37	GO:0021764	amygdala development
0.36	GO:0060996	dendritic spine development
0.36	GO:0021766	hippocampus development
0.36	GO:0007612	learning
0.36	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.36	GO:0007626	locomotory behavior
0.35	GO:0007623	circadian rhythm
0.35	GO:0008285	negative regulation of cell proliferation

0.82	GO:0016500	protein-hormone receptor activity
0.70	GO:0004930	G-protein coupled receptor activity
0.45	GO:0042277	peptide binding
0.38	GO:0008641	ubiquitin-like modifier activating enzyme activity
0.36	GO:0001653	peptide receptor activity
0.34	GO:0005515	protein binding

0.42	GO:0005887	integral component of plasma membrane
0.32	GO:0005737	cytoplasm

sp|P32592|ITB2_BOVIN
Integrin beta-2
Search

ITGB2

0.67	Integrin beta

0.82	GO:0007160	cell-matrix adhesion
0.80	GO:0007229	integrin-mediated signaling pathway
0.60	GO:0043315	positive regulation of neutrophil degranulation
0.59	GO:0034113	heterotypic cell-cell adhesion
0.59	GO:0007159	leukocyte cell-cell adhesion
0.58	GO:0032930	positive regulation of superoxide anion generation
0.58	GO:0043113	receptor clustering
0.57	GO:0030593	neutrophil chemotaxis
0.56	GO:0035987	endodermal cell differentiation
0.55	GO:0050730	regulation of peptidyl-tyrosine phosphorylation

0.65	GO:0004872	receptor activity
0.55	GO:0050839	cell adhesion molecule binding
0.53	GO:0019901	protein kinase binding
0.52	GO:0031072	heat shock protein binding
0.46	GO:0004871	signal transducer activity
0.40	GO:0001851	complement component C3b binding
0.39	GO:0001540	amyloid-beta binding
0.37	GO:0032403	protein complex binding
0.37	GO:0046982	protein heterodimerization activity
0.36	GO:0046872	metal ion binding

0.81	GO:0008305	integrin complex
0.55	GO:0044853	plasma membrane raft
0.53	GO:0009986	cell surface
0.51	GO:0099568	cytoplasmic region
0.38	GO:0070062	extracellular exosome
0.36	GO:0101003	ficolin-1-rich granule membrane
0.36	GO:0035579	specific granule membrane
0.36	GO:0070821	tertiary granule membrane
0.34	GO:0098552	side of membrane

sp|P32749|CHLE_BOVIN
Cholinesterase
Search

BCHE

0.51	Cholinesterase

0.60	GO:0051593	response to folic acid
0.59	GO:0014016	neuroblast differentiation
0.58	GO:0050805	negative regulation of synaptic transmission
0.57	GO:0043279	response to alkaloid
0.57	GO:0051384	response to glucocorticoid
0.56	GO:0007612	learning
0.55	GO:0050783	cocaine metabolic process
0.55	GO:0019695	choline metabolic process
0.54	GO:0008285	negative regulation of cell proliferation

0.85	GO:0003990	acetylcholinesterase activity
0.57	GO:0042802	identical protein binding
0.56	GO:0033265	choline binding
0.50	GO:0001540	amyloid-beta binding
0.45	GO:0019899	enzyme binding

0.66	GO:0005641	nuclear envelope lumen
0.64	GO:0005576	extracellular region
0.56	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0016020	membrane

0.85

EC:3.1.1.7

GO:0003990

sp|P32850|STX1A_BOVIN
Syntaxin-1A
Search

STX1A

0.74	Syntaxin-1A isoform A

0.77	GO:0017157	regulation of exocytosis
0.69	GO:0016192	vesicle-mediated transport
0.68	GO:0006886	intracellular protein transport
0.68	GO:0061025	membrane fusion
0.61	GO:0001956	positive regulation of neurotransmitter secretion
0.61	GO:2000463	positive regulation of excitatory postsynaptic potential
0.60	GO:1902803	regulation of synaptic vesicle transport
0.60	GO:0098693	regulation of synaptic vesicle cycle
0.55	GO:0097480	establishment of synaptic vesicle localization
0.55	GO:0099504	synaptic vesicle cycle

0.80	GO:0005484	SNAP receptor activity
0.75	GO:0000149	SNARE binding
0.55	GO:0019900	kinase binding
0.54	GO:0019869	chloride channel inhibitor activity
0.53	GO:0019855	calcium channel inhibitor activity
0.46	GO:0017022	myosin binding
0.45	GO:0005102	receptor binding
0.41	GO:0043008	ATP-dependent protein binding
0.40	GO:0019904	protein domain specific binding
0.40	GO:0048306	calcium-dependent protein binding

0.57	GO:0098793	presynapse
0.56	GO:0031201	SNARE complex
0.56	GO:0030424	axon
0.55	GO:0070382	exocytic vesicle
0.49	GO:0030658	transport vesicle membrane
0.49	GO:0031965	nuclear membrane
0.45	GO:0005887	integral component of plasma membrane
0.41	GO:0097060	synaptic membrane
0.40	GO:0034705	potassium channel complex
0.40	GO:0042641	actomyosin

sp|P32871|PK3CA_BOVIN
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Search

PIK3CA

0.95	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

0.83	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process
0.81	GO:0048015	phosphatidylinositol-mediated signaling
0.75	GO:0046854	phosphatidylinositol phosphorylation
0.59	GO:0044029	hypomethylation of CpG island
0.57	GO:2000653	regulation of genetic imprinting
0.57	GO:2000270	negative regulation of fibroblast apoptotic process
0.56	GO:2000811	negative regulation of anoikis
0.56	GO:0097009	energy homeostasis
0.55	GO:0060612	adipose tissue development
0.55	GO:0043491	protein kinase B signaling

0.84	GO:0016303	1-phosphatidylinositol-3-kinase activity
0.56	GO:0043560	insulin receptor substrate binding
0.53	GO:0030295	protein kinase activator activity
0.52	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.51	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity
0.37	GO:0004674	protein serine/threonine kinase activity
0.36	GO:1902379	chemoattractant activity involved in axon guidance
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0097367	carbohydrate derivative binding
0.34	GO:0008144	drug binding

0.62	GO:0005943	phosphatidylinositol 3-kinase complex, class IA
0.53	GO:0030027	lamellipodium
0.45	GO:0005622	intracellular
0.39	GO:0005886	plasma membrane
0.35	GO:0090723	growth cone part
0.30	GO:0016021	integral component of membrane

0.84	EC:2.7.1.137	GO:0016303
0.84	KEGG:R03362	GO:0016303

sp|P32876|AT5G1_BOVIN
ATP synthase F(0) complex subunit C1, mitochondrial
Search

0.86	ATP synthase lipid-binding protein, mitochondrial

0.76	GO:0015991	ATP hydrolysis coupled proton transport
0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.39	GO:0045471	response to ethanol
0.36	GO:0042407	cristae formation
0.35	GO:0006839	mitochondrial transport
0.34	GO:0046907	intracellular transport
0.34	GO:0007568	aging
0.33	GO:0055114	oxidation-reduction process

0.71	GO:0008289	lipid binding
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.44	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
0.44	GO:0019829	cation-transporting ATPase activity
0.35	GO:0004450	isocitrate dehydrogenase (NADP+) activity
0.35	GO:0015662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
0.33	GO:0005515	protein binding

0.72	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)
0.47	GO:0005753	mitochondrial proton-transporting ATP synthase complex
0.34	GO:0005741	mitochondrial outer membrane
0.30	GO:0016021	integral component of membrane

0.35

GO:0004450

sp|P33046|CTHL4_BOVIN
Cathelicidin-4
Search

0.96	Preprocathelicidin antimicrobial peptide

0.72	GO:0006952	defense response
0.58	GO:0009617	response to bacterium
0.46	GO:0044140	negative regulation of growth of symbiont on or near host surface
0.45	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.44	GO:0044130	negative regulation of growth of symbiont in host
0.44	GO:0051851	modification by host of symbiont morphology or physiology
0.43	GO:0031640	killing of cells of other organism
0.42	GO:0051818	disruption of cells of other organism involved in symbiotic interaction
0.38	GO:0019835	cytolysis
0.37	GO:0009620	response to fungus

0.33	GO:0005515	protein binding
0.32	GO:0046872	metal ion binding
0.32	GO:0003676	nucleic acid binding

0.66	GO:0005576	extracellular region
0.44	GO:0042581	specific granule
0.35	GO:1904724	tertiary granule lumen
0.34	GO:0034774	secretory granule lumen
0.33	GO:0042995	cell projection
0.30	GO:0016020	membrane

sp|P33072|LYOX_BOVIN
Protein-lysine 6-oxidase
Search

LOX

0.87	Lysyl oxidase a

0.57	GO:0048251	elastic fiber assembly
0.55	GO:0035904	aorta development
0.55	GO:0030199	collagen fibril organization
0.54	GO:0030324	lung development
0.53	GO:0048514	blood vessel morphogenesis
0.53	GO:0055114	oxidation-reduction process
0.52	GO:0007507	heart development
0.44	GO:0051216	cartilage development
0.43	GO:0007517	muscle organ development
0.42	GO:0022008	neurogenesis

0.77	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor
0.72	GO:0005507	copper ion binding
0.43	GO:0140096	catalytic activity, acting on a protein
0.35	GO:0005515	protein binding
0.34	GO:0035091	phosphatidylinositol binding

0.52	GO:0005581	collagen trimer
0.50	GO:0005578	proteinaceous extracellular matrix
0.50	GO:0005615	extracellular space
0.37	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.77

EC:1.4.3

GO:0016641

sp|P33097|AATC_BOVIN
Aspartate aminotransferase, cytoplasmic
Search

GOT1

0.49	Aspartate aminotransferase

0.62	GO:0006532	aspartate biosynthetic process
0.62	GO:0006114	glycerol biosynthetic process
0.61	GO:0019550	glutamate catabolic process to aspartate
0.61	GO:0006533	aspartate catabolic process
0.59	GO:0055089	fatty acid homeostasis
0.57	GO:0051384	response to glucocorticoid
0.56	GO:0032869	cellular response to insulin stimulus
0.56	GO:0006103	2-oxoglutarate metabolic process
0.55	GO:0007219	Notch signaling pathway
0.55	GO:0006107	oxaloacetate metabolic process

0.81	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity
0.78	GO:0070546	L-phenylalanine aminotransferase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.54	GO:0004609	phosphatidylserine decarboxylase activity
0.48	GO:0047801	L-cysteine:2-oxoglutarate aminotransferase activity
0.37	GO:0031406	carboxylic acid binding

0.50	GO:0005829	cytosol
0.50	GO:0005654	nucleoplasm
0.40	GO:0005739	mitochondrion
0.39	GO:0043679	axon terminus
0.38	GO:0005764	lysosome
0.36	GO:0070062	extracellular exosome

0.81	EC:2.6.1.1	GO:0004069
0.81	KEGG:R00355	GO:0004069

sp|P33433|HRG_BOVIN
Histidine-rich glycoprotein (Fragments)
Search

HRG

0.60	Histidine-rich glycoprotein (Fragments)

0.75	GO:0010593	negative regulation of lamellipodium assembly
0.75	GO:2000504	positive regulation of blood vessel remodeling
0.74	GO:2001027	negative regulation of endothelial cell chemotaxis
0.74	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway
0.73	GO:0033629	negative regulation of cell adhesion mediated by integrin
0.73	GO:0010951	negative regulation of endopeptidase activity
0.73	GO:0002839	positive regulation of immune response to tumor cell
0.71	GO:0051894	positive regulation of focal adhesion assembly
0.69	GO:0030193	regulation of blood coagulation
0.68	GO:0030168	platelet activation

0.77	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.70	GO:0043395	heparan sulfate proteoglycan binding
0.70	GO:0019865	immunoglobulin binding
0.68	GO:0008201	heparin binding
0.60	GO:0005102	receptor binding
0.54	GO:0008270	zinc ion binding
0.53	GO:0020037	heme binding
0.53	GO:0004867	serine-type endopeptidase inhibitor activity
0.37	GO:0043565	sequence-specific DNA binding
0.37	GO:0016852	sirohydrochlorin cobaltochelatase activity

0.59	GO:0036019	endolysosome
0.58	GO:0009986	cell surface
0.57	GO:0072562	blood microparticle
0.41	GO:0061474	phagolysosome membrane
0.37	GO:0070062	extracellular exosome
0.37	GO:0005634	nucleus
0.37	GO:0031093	platelet alpha granule lumen
0.34	GO:0031931	TORC1 complex
0.34	GO:0005667	transcription factor complex
0.33	GO:0019013	viral nucleocapsid

0.37

EC:4.99.1.3

GO:0016852

sp|P33545|DSC2_BOVIN
Desmocollin-2 (Fragment)
Search

DSC2

0.97	Desmocollin-2

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.57	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication
0.56	GO:0098911	regulation of ventricular cardiac muscle cell action potential
0.55	GO:0086091	regulation of heart rate by cardiac conduction
0.51	GO:0009267	cellular response to starvation
0.38	GO:0070268	cornification
0.38	GO:0050821	protein stabilization
0.37	GO:0001701	in utero embryonic development
0.34	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.34	GO:0043312	neutrophil degranulation

0.70	GO:0005509	calcium ion binding
0.40	GO:0045295	gamma-catenin binding
0.36	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication

0.58	GO:0030057	desmosome
0.56	GO:0005886	plasma membrane
0.55	GO:0014704	intercalated disc
0.53	GO:0005913	cell-cell adherens junction
0.49	GO:0031982	vesicle
0.41	GO:0044444	cytoplasmic part
0.40	GO:0043229	intracellular organelle
0.40	GO:0043230	extracellular organelle
0.38	GO:0005615	extracellular space
0.34	GO:0005921	gap junction

sp|P33567|SYUB_BOVIN
Beta-synuclein
Search

SNCB

0.91	Gamma-synuclein

0.68	GO:0014059	regulation of dopamine secretion
0.61	GO:0042417	dopamine metabolic process
0.59	GO:0043524	negative regulation of neuron apoptotic process
0.59	GO:0050808	synapse organization
0.56	GO:0007268	chemical synaptic transmission
0.51	GO:0051945	negative regulation of catecholamine uptake involved in synaptic transmission
0.51	GO:0051621	regulation of norepinephrine uptake
0.51	GO:1903284	positive regulation of glutathione peroxidase activity
0.51	GO:1903285	positive regulation of hydrogen peroxide catabolic process
0.51	GO:1904715	negative regulation of chaperone-mediated autophagy

0.62	GO:1903136	cuprous ion binding
0.51	GO:0005509	calcium ion binding
0.50	GO:0048156	tau protein binding
0.49	GO:0050544	arachidonic acid binding
0.49	GO:0043014	alpha-tubulin binding
0.49	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.49	GO:0030544	Hsp70 protein binding
0.48	GO:0019894	kinesin binding
0.47	GO:0070840	dynein complex binding
0.47	GO:0051219	phosphoprotein binding

0.59	GO:0016234	inclusion body
0.56	GO:0045202	synapse
0.50	GO:0031092	platelet alpha granule membrane
0.49	GO:0043025	neuronal cell body
0.48	GO:0030424	axon
0.48	GO:0030426	growth cone
0.46	GO:0005739	mitochondrion
0.46	GO:0048471	perinuclear region of cytoplasm
0.45	GO:0005615	extracellular space
0.45	GO:0005938	cell cortex

0.38

EC:1

GO:0016491

sp|P33672|PSB3_BOVIN
Proteasome subunit beta type-3
Search

PSMB3

0.53	Proteasome subunit beta type

0.77	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.35	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation
0.35	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia
0.35	GO:0070498	interleukin-1-mediated signaling pathway
0.35	GO:0038061	NIK/NF-kappaB signaling

0.76	GO:0070003	threonine-type peptidase activity
0.64	GO:0004175	endopeptidase activity
0.33	GO:0005515	protein binding

0.81	GO:0019774	proteasome core complex, beta-subunit complex
0.58	GO:0005634	nucleus
0.46	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part

sp|P33946|ERD21_BOVIN
ER lumen protein-retaining receptor 1
Search

KDELR1

0.66	ER lumen protein-retaining receptor

0.84	GO:0006621	protein retention in ER lumen
0.64	GO:0015031	protein transport
0.52	GO:0002369	T cell cytokine production
0.52	GO:0070231	T cell apoptotic process
0.50	GO:0030217	T cell differentiation
0.41	GO:0016192	vesicle-mediated transport
0.34	GO:0046907	intracellular transport
0.33	GO:0006629	lipid metabolic process

0.84	GO:0046923	ER retention sequence binding
0.32	GO:0016787	hydrolase activity

0.71	GO:0005789	endoplasmic reticulum membrane
0.51	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.51	GO:0005801	cis-Golgi network
0.46	GO:0005794	Golgi apparatus
0.40	GO:0030663	COPI-coated vesicle membrane
0.36	GO:0070062	extracellular exosome
0.35	GO:0030133	transport vesicle
0.30	GO:0016021	integral component of membrane

0.32

GO:0016787

sp|P34933|HSP72_BOVIN
Heat shock-related 70 kDa protein 2
Search

HSPA2

0.61	Inducible heat shock protein 70

0.64	GO:0009409	response to cold
0.60	GO:0009408	response to heat
0.56	GO:0031662	positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle
0.55	GO:1901896	positive regulation of calcium-transporting ATPase activity
0.55	GO:0070194	synaptonemal complex disassembly
0.54	GO:0090084	negative regulation of inclusion body assembly
0.53	GO:0007141	male meiosis I
0.51	GO:0007286	spermatid development
0.48	GO:0042026	protein refolding
0.39	GO:0032570	response to progesterone

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0097718	disordered domain specific binding
0.47	GO:0008289	lipid binding
0.46	GO:0019899	enzyme binding
0.46	GO:0051082	unfolded protein binding
0.40	GO:0033142	progesterone receptor binding
0.35	GO:0055131	C3HC4-type RING finger domain binding

0.54	GO:0036128	CatSper complex
0.54	GO:0072687	meiotic spindle
0.53	GO:0001673	male germ cell nucleus
0.52	GO:0000795	synaptonemal complex
0.51	GO:0043209	myelin sheath
0.48	GO:0009986	cell surface
0.46	GO:0005829	cytosol
0.42	GO:0005739	mitochondrion
0.39	GO:0043204	perikaryon
0.38	GO:0072562	blood microparticle

0.33

GO:0016887

sp|P34942|NDUAA_BOVIN
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial
Search

NDUFA10

0.87	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial

0.74	GO:0006120	mitochondrial electron transport, NADH to ubiquinone
0.56	GO:0032981	mitochondrial respiratory chain complex I assembly
0.34	GO:0042221	response to chemical
0.34	GO:0009165	nucleotide biosynthetic process
0.33	GO:0007608	sensory perception of smell
0.33	GO:0050906	detection of stimulus involved in sensory perception
0.33	GO:0007186	G-protein coupled receptor signaling pathway

0.46	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.35	GO:0019206	nucleoside kinase activity
0.33	GO:0004984	olfactory receptor activity
0.33	GO:0004930	G-protein coupled receptor activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.81	GO:0005747	mitochondrial respiratory chain complex I
0.69	GO:0005759	mitochondrial matrix
0.52	GO:0043209	myelin sheath
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.46

GO:0008137

sp|P34943|NDUA9_BOVIN
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial
Search

NDUFA9

0.37	NADH-ubiquinone oxidoreductase 39 kDa subunit

0.54	GO:1901006	ubiquinone-6 biosynthetic process
0.44	GO:0032981	mitochondrial respiratory chain complex I assembly
0.42	GO:0007623	circadian rhythm
0.41	GO:0055114	oxidation-reduction process
0.40	GO:0001666	response to hypoxia
0.38	GO:0006694	steroid biosynthetic process
0.37	GO:0009749	response to glucose
0.34	GO:0006814	sodium ion transport
0.33	GO:0006119	oxidative phosphorylation

0.54	GO:0050662	coenzyme binding
0.46	GO:0003954	NADH dehydrogenase activity
0.39	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity
0.37	GO:0032403	protein complex binding
0.35	GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
0.33	GO:1901265	nucleoside phosphate binding
0.33	GO:0036094	small molecule binding

0.55	GO:0005747	mitochondrial respiratory chain complex I
0.42	GO:0005759	mitochondrial matrix
0.35	GO:0005654	nucleoplasm
0.30	GO:0016021	integral component of membrane

0.46

EC:1.6.99.3

GO:0003954

sp|P34955|A1AT_BOVIN
Alpha-1-antiproteinase
Search

SERPINA1

0.87	alpha-1-antitrypsin precursor

0.58	GO:0010951	negative regulation of endopeptidase activity
0.45	GO:0006953	acute-phase response
0.39	GO:0034097	response to cytokine
0.39	GO:0043434	response to peptide hormone
0.36	GO:0002576	platelet degranulation
0.36	GO:0006487	protein N-linked glycosylation
0.36	GO:0046687	response to chromate
0.35	GO:0033986	response to methanol
0.35	GO:0042750	hibernation
0.35	GO:0034014	response to triglyceride

0.60	GO:0004867	serine-type endopeptidase inhibitor activity
0.52	GO:0002020	protease binding
0.48	GO:0042802	identical protein binding

0.73	GO:0005615	extracellular space
0.47	GO:0005794	Golgi apparatus
0.47	GO:0005783	endoplasmic reticulum
0.37	GO:1903561	extracellular vesicle
0.36	GO:0034774	secretory granule lumen
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0031091	platelet alpha granule
0.35	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane
0.34	GO:0030134	COPII-coated ER to Golgi transport vesicle
0.34	GO:0042827	platelet dense granule

sp|P34974|ACTHR_BOVIN
Adrenocorticotropic hormone receptor
Search

MC2R

0.97	Adrenocorticotropic hormone receptor

0.71	GO:0007218	neuropeptide signaling pathway
0.57	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.44	GO:0030819	positive regulation of cAMP biosynthetic process
0.44	GO:0060259	regulation of feeding behavior
0.42	GO:0048521	negative regulation of behavior
0.42	GO:0032501	multicellular organismal process
0.39	GO:0040008	regulation of growth
0.39	GO:0003006	developmental process involved in reproduction
0.39	GO:0006112	energy reserve metabolic process
0.38	GO:0048856	anatomical structure development

0.84	GO:0004977	melanocortin receptor activity
0.73	GO:0008188	neuropeptide receptor activity
0.39	GO:0042923	neuropeptide binding
0.35	GO:0031625	ubiquitin protein ligase binding
0.32	GO:0003924	GTPase activity
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0032561	guanyl ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.55	GO:0005886	plasma membrane
0.38	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|P34979|PE2R3_BOVIN
Prostaglandin E2 receptor EP3 subtype
Search

PTGER3

0.97	Prostaglandin E receptor 3

0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.51	GO:0060455	negative regulation of gastric acid secretion
0.51	GO:0014827	intestine smooth muscle contraction
0.40	GO:0031622	positive regulation of fever generation
0.38	GO:0035810	positive regulation of urine volume
0.38	GO:0001660	fever generation
0.38	GO:0015701	bicarbonate transport
0.37	GO:0032496	response to lipopolysaccharide
0.37	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.37	GO:1990767	prostaglandin receptor internalization

0.85	GO:0004957	prostaglandin E receptor activity
0.48	GO:0004960	thromboxane receptor activity
0.35	GO:0005515	protein binding
0.33	GO:0004958	prostaglandin F receptor activity

0.37	GO:0005886	plasma membrane
0.36	GO:0005635	nuclear envelope
0.36	GO:1990769	proximal neuron projection
0.35	GO:0005903	brush border
0.35	GO:0043025	neuronal cell body
0.34	GO:0120038	plasma membrane bounded cell projection part
0.34	GO:0009986	cell surface
0.33	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

sp|P34993|SSR2_BOVIN
Somatostatin receptor type 2
Search

SSTR2

0.97	Somatostatin receptor type 2

0.85	GO:0038169	somatostatin receptor signaling pathway
0.76	GO:0009755	hormone-mediated signaling pathway
0.56	GO:0007187	G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
0.53	GO:0007218	neuropeptide signaling pathway
0.50	GO:0071385	cellular response to glucocorticoid stimulus
0.50	GO:0071392	cellular response to estradiol stimulus
0.48	GO:0008285	negative regulation of cell proliferation
0.39	GO:0030432	peristalsis
0.38	GO:0021549	cerebellum development
0.38	GO:0006937	regulation of muscle contraction

0.85	GO:0004994	somatostatin receptor activity
0.56	GO:0030165	PDZ domain binding
0.52	GO:0042923	neuropeptide binding
0.34	GO:0017046	peptide hormone binding
0.34	GO:0046982	protein heterodimerization activity

0.48	GO:0005829	cytosol
0.47	GO:0043005	neuron projection
0.43	GO:0005887	integral component of plasma membrane
0.35	GO:0098802	plasma membrane receptor complex

sp|P35071|CFTR_BOVIN
Cystic fibrosis transmembrane conductance regulator
Search

CFTR

0.93	Cystic fibrosis transmembrane conductance regulator

0.76	GO:1902476	chloride transmembrane transport
0.71	GO:0035377	transepithelial water transport
0.70	GO:0060081	membrane hyperpolarization
0.70	GO:0045852	pH elevation
0.69	GO:1904321	response to forskolin
0.68	GO:0048240	sperm capacitation
0.68	GO:0015701	bicarbonate transport
0.68	GO:0071320	cellular response to cAMP
0.67	GO:0050891	multicellular organismal water homeostasis
0.66	GO:1901655	cellular response to ketone

0.86	GO:0005260	intracellularly ATP-gated chloride channel activity
0.69	GO:0019869	chloride channel inhibitor activity
0.68	GO:0015106	bicarbonate transmembrane transporter activity
0.65	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.54	GO:0030554	adenyl nucleotide binding
0.54	GO:0030165	PDZ domain binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.48	GO:0019899	enzyme binding

0.81	GO:0034707	chloride channel complex
0.65	GO:0016324	apical plasma membrane
0.64	GO:0055037	recycling endosome
0.62	GO:0005769	early endosome
0.57	GO:0005789	endoplasmic reticulum membrane
0.56	GO:0098588	bounding membrane of organelle
0.56	GO:0044440	endosomal part
0.54	GO:0005887	integral component of plasma membrane
0.53	GO:0005791	rough endoplasmic reticulum
0.52	GO:0098805	whole membrane

0.86

EC:3.6.3.49

GO:0005260

sp|P35246|SFTPD_BOVIN
Pulmonary surfactant-associated protein D
Search

SFTPD

0.93	Pulmonary surfactant-associated protein D

0.63	GO:1905226	regulation of adhesion of symbiont to host epithelial cell
0.62	GO:0043129	surfactant homeostasis
0.61	GO:0043152	induction of bacterial agglutination
0.61	GO:0052405	negative regulation by host of symbiont molecular function
0.60	GO:0048286	lung alveolus development
0.46	GO:0007585	respiratory gaseous exchange
0.44	GO:0045087	innate immune response
0.41	GO:0002244	hematopoietic progenitor cell differentiation
0.40	GO:0032703	negative regulation of interleukin-2 production
0.39	GO:0050828	regulation of liquid surface tension

0.50	GO:0005201	extracellular matrix structural constituent
0.45	GO:0042802	identical protein binding
0.43	GO:0030246	carbohydrate binding
0.38	GO:0001530	lipopolysaccharide binding
0.36	GO:0042302	structural constituent of cuticle
0.36	GO:0005178	integrin binding
0.35	GO:0048407	platelet-derived growth factor binding
0.35	GO:0036094	small molecule binding
0.35	GO:0002020	protease binding
0.34	GO:0008201	heparin binding

0.73	GO:0005581	collagen trimer
0.46	GO:0005578	proteinaceous extracellular matrix
0.43	GO:0005615	extracellular space
0.40	GO:0044420	extracellular matrix component
0.38	GO:0005771	multivesicular body
0.38	GO:0005791	rough endoplasmic reticulum
0.37	GO:0019867	outer membrane
0.35	GO:0099512	supramolecular fiber
0.35	GO:0042599	lamellar body
0.34	GO:0045334	clathrin-coated endocytic vesicle

0.33

EC:3.2.1

GO:0004553

sp|P35350|ACKR4_BOVIN
Atypical chemokine receptor 4
Search

ACKR4

0.97	Atypical chemokine receptor 4

0.81	GO:0070098	chemokine-mediated signaling pathway
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.69	GO:0006935	chemotaxis
0.65	GO:0006898	receptor-mediated endocytosis
0.48	GO:0002305	CD8-positive, gamma-delta intraepithelial T cell differentiation
0.48	GO:0006955	immune response
0.37	GO:0006954	inflammatory response
0.37	GO:0001570	vasculogenesis
0.37	GO:0001525	angiogenesis
0.36	GO:0002685	regulation of leukocyte migration

0.82	GO:0004950	chemokine receptor activity
0.79	GO:0019956	chemokine binding
0.73	GO:0005044	scavenger receptor activity
0.38	GO:0015026	coreceptor activity
0.36	GO:0004982	N-formyl peptide receptor activity
0.35	GO:0004875	complement receptor activity
0.33	GO:0035091	phosphatidylinositol binding
0.32	GO:0004969	histamine receptor activity
0.32	GO:0009881	photoreceptor activity

0.44	GO:0009986	cell surface
0.39	GO:0055037	recycling endosome
0.38	GO:0005769	early endosome
0.36	GO:0005886	plasma membrane
0.33	GO:0098552	side of membrane
0.32	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

sp|P35376|FSHR_BOVIN
Follicle-stimulating hormone receptor
Search

FSHR

0.83	Follicle-stimulating hormone receptor

0.86	GO:0042699	follicle-stimulating hormone signaling pathway
0.64	GO:0001545	primary ovarian follicle growth
0.60	GO:0060408	regulation of acetylcholine metabolic process
0.59	GO:0045670	regulation of osteoclast differentiation
0.59	GO:0060011	Sertoli cell proliferation
0.58	GO:0009992	cellular water homeostasis
0.58	GO:0035093	spermatogenesis, exchange of chromosomal proteins
0.58	GO:0045779	negative regulation of bone resorption
0.58	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway
0.58	GO:0060009	Sertoli cell development

0.86	GO:0004963	follicle-stimulating hormone receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.45	GO:0001653	peptide receptor activity
0.40	GO:0017046	peptide hormone binding
0.34	GO:0005515	protein binding

0.54	GO:0005886	plasma membrane
0.51	GO:0009986	cell surface
0.38	GO:0005768	endosome
0.30	GO:0016021	integral component of membrane

sp|P35384|CASR_BOVIN
Extracellular calcium-sensing receptor
Search

CASR

0.87	Extracellular calcium-sensing receptor

0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.68	GO:0005513	detection of calcium ion
0.64	GO:0055074	calcium ion homeostasis
0.63	GO:0070509	calcium ion import
0.61	GO:0072503	cellular divalent inorganic cation homeostasis
0.61	GO:0051924	regulation of calcium ion transport
0.60	GO:0032781	positive regulation of ATPase activity
0.58	GO:0006875	cellular metal ion homeostasis
0.55	GO:0010628	positive regulation of gene expression
0.46	GO:0042311	vasodilation

0.71	GO:0004930	G-protein coupled receptor activity
0.58	GO:0016597	amino acid binding
0.58	GO:0042803	protein homodimerization activity
0.55	GO:0005509	calcium ion binding
0.44	GO:0044325	ion channel binding
0.44	GO:0005178	integrin binding
0.42	GO:0019808	polyamine binding
0.42	GO:0019901	protein kinase binding
0.39	GO:0000287	magnesium ion binding
0.37	GO:0004435	phosphatidylinositol phospholipase C activity

0.53	GO:0005887	integral component of plasma membrane
0.46	GO:0043679	axon terminus
0.43	GO:0016323	basolateral plasma membrane
0.43	GO:0016324	apical plasma membrane
0.43	GO:0043025	neuronal cell body
0.43	GO:0030424	axon
0.42	GO:0009986	cell surface
0.38	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm

0.37	EC:3.1.4.11	GO:0004435
0.37	KEGG:R03435	GO:0004435

sp|P35445|COMP_BOVIN
Cartilage oligomeric matrix protein
Search

COMP

0.75	Cartilage oligomeric matrix protein variant (Fragment)

0.81	GO:0030198	extracellular matrix organization
0.72	GO:0007155	cell adhesion
0.53	GO:0003417	growth plate cartilage development
0.50	GO:0060173	limb development
0.48	GO:0043066	negative regulation of apoptotic process
0.46	GO:0051451	myoblast migration
0.46	GO:0048266	behavioral response to pain
0.46	GO:0090023	positive regulation of neutrophil chemotaxis
0.45	GO:0034103	regulation of tissue remodeling
0.45	GO:0001938	positive regulation of endothelial cell proliferation

0.70	GO:0005509	calcium ion binding
0.54	GO:0008201	heparin binding
0.52	GO:0043395	heparan sulfate proteoglycan binding
0.51	GO:0032403	protein complex binding
0.51	GO:0002020	protease binding
0.43	GO:0050839	cell adhesion molecule binding
0.42	GO:0005102	receptor binding
0.36	GO:0030545	receptor regulator activity
0.33	GO:0001968	fibronectin binding
0.33	GO:0043237	laminin-1 binding

0.74	GO:0031012	extracellular matrix
0.50	GO:0005615	extracellular space
0.45	GO:0016529	sarcoplasmic reticulum
0.34	GO:1903561	extracellular vesicle
0.33	GO:0031594	neuromuscular junction

sp|P35466|S10A4_BOVIN
Protein S100-A4
Search

sp|P35478|CYTX_BOVIN
Stefin-C
Search

CSTB

0.91	LOW QUALITY PROTEIN: cystatin-B

0.76	GO:0010951	negative regulation of endopeptidase activity
0.49	GO:0008344	adult locomotory behavior
0.37	GO:0030216	keratinocyte differentiation
0.37	GO:0018149	peptide cross-linking
0.36	GO:0043312	neutrophil degranulation
0.36	GO:0098609	cell-cell adhesion
0.33	GO:0007017	microtubule-based process
0.33	GO:0043043	peptide biosynthetic process
0.33	GO:2000116	regulation of cysteine-type endopeptidase activity
0.33	GO:0007186	G-protein coupled receptor signaling pathway

0.82	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.53	GO:0002020	protease binding
0.36	GO:0030674	protein binding, bridging
0.35	GO:0005198	structural molecule activity
0.34	GO:0003723	RNA binding
0.33	GO:0004930	G-protein coupled receptor activity

0.48	GO:0005615	extracellular space
0.48	GO:0005730	nucleolus
0.47	GO:0005829	cytosol
0.37	GO:0001533	cornified envelope
0.37	GO:1903561	extracellular vesicle
0.36	GO:1904724	tertiary granule lumen
0.36	GO:1904813	ficolin-1-rich granule lumen
0.36	GO:0034774	secretory granule lumen
0.34	GO:0030286	dynein complex
0.33	GO:0005840	ribosome

sp|P35507|KC1B_BOVIN
Casein kinase I isoform beta
Search

0.75	Casein kinase 1 protein catalytic subunit

0.63	GO:0006468	protein phosphorylation
0.50	GO:0018209	peptidyl-serine modification
0.47	GO:0006909	phagocytosis
0.47	GO:0016055	Wnt signaling pathway
0.45	GO:0045104	intermediate filament cytoskeleton organization
0.45	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.43	GO:1904424	regulation of GTP binding
0.43	GO:0008360	regulation of cell shape
0.42	GO:0007030	Golgi organization
0.41	GO:0048856	anatomical structure development

0.66	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0004610	phosphoacetylglucosamine mutase activity
0.35	GO:0005515	protein binding
0.34	GO:0042277	peptide binding
0.34	GO:0000287	magnesium ion binding
0.34	GO:0005057	signal transducer activity, downstream of receptor

0.44	GO:0045095	keratin filament
0.44	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex
0.44	GO:0005815	microtubule organizing center
0.44	GO:0016607	nuclear speck
0.43	GO:0030877	beta-catenin destruction complex
0.43	GO:0044441	ciliary part
0.41	GO:0005829	cytosol
0.41	GO:0000777	condensed chromosome kinetochore
0.37	GO:0030529	intracellular ribonucleoprotein complex
0.35	GO:0000139	Golgi membrane

0.66	EC:2.7.11	GO:0004674
0.37	KEGG:R08193	GO:0004610

sp|P35508|KC1D_BOVIN
Casein kinase I isoform delta
Search

CSNK1D

0.73	Casein kinase I

0.63	GO:0006468	protein phosphorylation
0.52	GO:2000052	positive regulation of non-canonical Wnt signaling pathway
0.51	GO:0032922	circadian regulation of gene expression
0.51	GO:0018209	peptidyl-serine modification
0.51	GO:0071539	protein localization to centrosome
0.51	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.51	GO:0061512	protein localization to cilium
0.50	GO:1905515	non-motile cilium assembly
0.50	GO:0042752	regulation of circadian rhythm
0.50	GO:0034067	protein localization to Golgi apparatus

0.63	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0045296	cadherin binding
0.37	GO:0042277	peptide binding

0.49	GO:0005876	spindle microtubule
0.48	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0005813	centrosome
0.45	GO:0005794	Golgi apparatus
0.43	GO:0005634	nucleus
0.40	GO:0005886	plasma membrane
0.37	GO:0043005	neuron projection
0.35	GO:0098588	bounding membrane of organelle
0.35	GO:0005829	cytosol
0.35	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment

sp|P35509|KC1G3_BOVIN
Casein kinase I isoform gamma-3 (Fragment)
Search

CSNK1G3

0.80	Casein kinase I

0.62	GO:0006468	protein phosphorylation
0.54	GO:0018209	peptidyl-serine modification
0.45	GO:0016055	Wnt signaling pathway
0.43	GO:0006897	endocytosis
0.42	GO:0008360	regulation of cell shape
0.34	GO:0030148	sphingolipid biosynthetic process

0.69	GO:0004674	protein serine/threonine kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0051219	phosphoprotein binding
0.37	GO:0042277	peptide binding
0.35	GO:0000287	magnesium ion binding

0.40	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.69

GO:0004674

sp|P35526|CLIC5_BOVIN
Chloride intracellular channel protein 5
Search

CLIC5

0.67	Chloride intracellular channel protein 5

0.76	GO:1902476	chloride transmembrane transport
0.75	GO:0034765	regulation of ion transmembrane transport
0.55	GO:0007605	sensory perception of sound
0.54	GO:0060088	auditory receptor cell stereocilium organization
0.50	GO:0002024	diet induced thermogenesis
0.48	GO:0050885	neuromuscular process controlling balance
0.45	GO:0006749	glutathione metabolic process
0.42	GO:0008104	protein localization
0.37	GO:0001525	angiogenesis
0.36	GO:0061299	retina vasculature morphogenesis in camera-type eye

0.76	GO:0005254	chloride channel activity
0.72	GO:0022832	voltage-gated channel activity
0.70	GO:0022839	ion gated channel activity
0.70	GO:0008381	mechanosensitive ion channel activity
0.46	GO:0004364	glutathione transferase activity
0.33	GO:0005515	protein binding

0.80	GO:0034707	chloride channel complex
0.48	GO:0032420	stereocilium
0.48	GO:0015629	actin cytoskeleton
0.48	GO:0005737	cytoplasm
0.41	GO:0005634	nucleus
0.39	GO:0005815	microtubule organizing center
0.37	GO:0031982	vesicle
0.37	GO:0012505	endomembrane system
0.36	GO:0043230	extracellular organelle
0.36	GO:0005902	microvillus

0.46

EC:2.5.1.18

GO:0004364

sp|P35541|SAA_BOVIN
Serum amyloid A protein
Search

0.94	Serum amyloid A protein (Fragment)

0.85	GO:0006953	acute-phase response
0.53	GO:0050918	positive chemotaxis
0.51	GO:0060326	cell chemotaxis
0.42	GO:0010739	positive regulation of protein kinase A signaling
0.42	GO:0050996	positive regulation of lipid catabolic process
0.41	GO:0043410	positive regulation of MAPK cascade
0.41	GO:0033138	positive regulation of peptidyl-serine phosphorylation
0.41	GO:0070372	regulation of ERK1 and ERK2 cascade
0.39	GO:0044242	cellular lipid catabolic process
0.39	GO:0045892	negative regulation of transcription, DNA-templated

0.54	GO:0042056	chemoattractant activity
0.38	GO:0008201	heparin binding
0.38	GO:0035662	Toll-like receptor 4 binding
0.36	GO:0001664	G-protein coupled receptor binding
0.34	GO:0042802	identical protein binding

0.85	GO:0034364	high-density lipoprotein particle
0.36	GO:0005881	cytoplasmic microtubule
0.36	GO:0070062	extracellular exosome
0.35	GO:0071682	endocytic vesicle lumen
0.30	GO:0016020	membrane

sp|P35604|COPZ1_BOVIN
Coatomer subunit zeta-1
Search

COPZ1

0.92	Coatomer protein complex subunit zeta

0.65	GO:0015031	protein transport
0.62	GO:0016192	vesicle-mediated transport
0.62	GO:0046907	intracellular transport
0.62	GO:0034613	cellular protein localization
0.48	GO:1901998	toxin transport
0.45	GO:0002088	lens development in camera-type eye

0.34

GO:0003723

RNA binding

0.69	GO:0030117	membrane coat
0.52	GO:0030663	COPI-coated vesicle membrane
0.49	GO:0044431	Golgi apparatus part
0.37	GO:0031984	organelle subcompartment
0.35	GO:0030133	transport vesicle
0.35	GO:0019028	viral capsid
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0044432	endoplasmic reticulum part
0.34	GO:0005829	cytosol
0.34	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane

sp|P35605|COPB2_BOVIN
Coatomer subunit beta'
Search

COPB2

0.63	Coatomer subunit beta'

0.69	GO:0006886	intracellular protein transport
0.69	GO:0016192	vesicle-mediated transport
0.52	GO:1901998	toxin transport
0.47	GO:0030903	notochord development
0.46	GO:0061053	somite development

0.62	GO:0005198	structural molecule activity
0.37	GO:0005080	protein kinase C binding
0.32	GO:0016740	transferase activity

0.75	GO:0030117	membrane coat
0.73	GO:0030663	COPI-coated vesicle membrane
0.67	GO:0000139	Golgi membrane
0.38	GO:0005829	cytosol
0.36	GO:0030133	transport vesicle
0.34	GO:0099503	secretory vesicle
0.34	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016740

sp|P35662|CYLC1_BOVIN
Cylicin-1
Search

CYLC1

0.97	Testis cDNA, clone: QtsA-16859, similar to human cylicin, basic protein of sperm head cytoskeleton 1(CYLC1)

0.69	GO:0007010	cytoskeleton organization
0.40	GO:0007283	spermatogenesis
0.39	GO:0030154	cell differentiation
0.38	GO:0007275	multicellular organism development
0.36	GO:0000412	histone peptidyl-prolyl isomerization
0.34	GO:0006182	cGMP biosynthetic process
0.34	GO:0009253	peptidoglycan catabolic process
0.33	GO:0000027	ribosomal large subunit assembly
0.33	GO:0006839	mitochondrial transport
0.33	GO:0035556	intracellular signal transduction

0.75	GO:0005200	structural constituent of cytoskeleton
0.36	GO:0005528	FK506 binding
0.35	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.34	GO:0008270	zinc ion binding
0.34	GO:0004383	guanylate cyclase activity
0.34	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity
0.33	GO:0003723	RNA binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0016491	oxidoreductase activity

0.64	GO:0043159	acrosomal matrix
0.44	GO:0033150	cytoskeletal calyx
0.38	GO:0005634	nucleus
0.34	GO:0043233	organelle lumen
0.33	GO:0030686	90S preribosome
0.33	GO:0030687	preribosome, large subunit precursor
0.32	GO:0045281	succinate dehydrogenase complex
0.32	GO:0031966	mitochondrial membrane
0.32	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

0.35

GO:0003755

sp|P35705|PRDX3_BOVIN
Thioredoxin-dependent peroxide reductase, mitochondrial
Search

PRDX3

0.93	Thioredoxin-dependent peroxide reductase

0.69	GO:0098869	cellular oxidant detoxification
0.68	GO:0045454	cell redox homeostasis
0.56	GO:0018171	peptidyl-cysteine oxidation
0.53	GO:0051881	regulation of mitochondrial membrane potential
0.53	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.52	GO:0042542	response to hydrogen peroxide
0.52	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.51	GO:0001893	maternal placenta development
0.51	GO:0030099	myeloid cell differentiation
0.51	GO:0032496	response to lipopolysaccharide

0.74	GO:0051920	peroxiredoxin activity
0.54	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.52	GO:0008022	protein C-terminus binding
0.50	GO:0019901	protein kinase binding
0.49	GO:0004601	peroxidase activity
0.48	GO:0042802	identical protein binding
0.35	GO:0015075	ion transmembrane transporter activity
0.35	GO:0008785	alkyl hydroperoxide reductase activity

0.55	GO:0008385	IkappaB kinase complex
0.51	GO:0043209	myelin sheath
0.51	GO:0005769	early endosome
0.43	GO:0005739	mitochondrion
0.42	GO:0043234	protein complex
0.36	GO:0070062	extracellular exosome
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.74	EC:1.11.1.15	GO:0051920
0.49	KEGG:R03532	GO:0004601

sp|P35720|C560_BOVIN
Succinate dehydrogenase cytochrome b560 subunit, mitochondrial
Search

SDHC

0.95	Chain C, Avian Respiratory Complex Ii With Oxaloacetate And Ubiquinone

0.70	GO:0006099	tricarboxylic acid cycle
0.60	GO:0022900	electron transport chain
0.43	GO:0006119	oxidative phosphorylation
0.39	GO:0008340	determination of adult lifespan
0.37	GO:0006979	response to oxidative stress

0.76	GO:0000104	succinate dehydrogenase activity
0.61	GO:0009055	electron transfer activity
0.52	GO:0046872	metal ion binding
0.38	GO:0020037	heme binding
0.37	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor
0.34	GO:0005515	protein binding
0.32	GO:0048038	quinone binding
0.32	GO:0051287	NAD binding
0.32	GO:0016651	oxidoreductase activity, acting on NAD(P)H
0.32	GO:0030554	adenyl nucleotide binding

0.78	GO:0045281	succinate dehydrogenase complex
0.51	GO:0045283	fumarate reductase complex
0.48	GO:0005746	mitochondrial respiratory chain
0.47	GO:0098800	inner mitochondrial membrane protein complex
0.30	GO:0016021	integral component of membrane

0.76

EC:1.3.99.1

GO:0000104

sp|P35722|NEUG_BOVIN
Neurogranin
Search

NRGN

0.97	Neurogranin

0.59	GO:0007339	binding of sperm to zona pellucida
0.51	GO:1900273	positive regulation of long-term synaptic potentiation
0.49	GO:0008306	associative learning
0.48	GO:0021537	telencephalon development
0.38	GO:0007165	signal transduction
0.36	GO:0040008	regulation of growth
0.35	GO:0016310	phosphorylation
0.34	GO:0006413	translational initiation

0.72	GO:0005516	calmodulin binding
0.50	GO:0070300	phosphatidic acid binding
0.49	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.38	GO:0032027	myosin light chain binding
0.35	GO:0016301	kinase activity
0.34	GO:0003743	translation initiation factor activity
0.34	GO:0005509	calcium ion binding
0.34	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding

0.52	GO:0044327	dendritic spine head
0.48	GO:0014069	postsynaptic density
0.48	GO:0012510	trans-Golgi network transport vesicle membrane
0.47	GO:0043025	neuronal cell body
0.47	GO:0030424	axon
0.44	GO:0005938	cell cortex
0.41	GO:0031966	mitochondrial membrane
0.41	GO:0030054	cell junction
0.41	GO:0005634	nucleus

sp|P35816|PDP1_BOVIN
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial
Search

PDP1

0.90	Pyruvate dehydrogenase acetyl-transferring-phosphatase 1

0.72	GO:0006470	protein dephosphorylation
0.36	GO:0010826	negative regulation of centrosome duplication
0.36	GO:0060271	cilium assembly
0.35	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate
0.34	GO:0043085	positive regulation of catalytic activity

0.77	GO:0004722	protein serine/threonine phosphatase activity
0.54	GO:0046872	metal ion binding
0.41	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity
0.34	GO:0005515	protein binding
0.34	GO:0044877	macromolecular complex binding

0.38	GO:0005759	mitochondrial matrix
0.36	GO:0036038	MKS complex
0.30	GO:0031224	intrinsic component of membrane

0.41

EC:3.1.3.43

GO:0004741

sp|P35833|CSF3_BOVIN
Granulocyte colony-stimulating factor
Search

CSF3

0.96	Colony stimulating factor 3

0.81	GO:2000251	positive regulation of actin cytoskeleton reorganization
0.79	GO:0042993	positive regulation of transcription factor import into nucleus
0.79	GO:0045639	positive regulation of myeloid cell differentiation
0.79	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling
0.78	GO:0051897	positive regulation of protein kinase B signaling
0.78	GO:0033138	positive regulation of peptidyl-serine phosphorylation
0.78	GO:0032092	positive regulation of protein binding
0.76	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
0.76	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response

0.86	GO:0005130	granulocyte colony-stimulating factor receptor binding
0.81	GO:0005125	cytokine activity
0.66	GO:0019899	enzyme binding
0.48	GO:0008083	growth factor activity

0.66	GO:0005576	extracellular region
0.30	GO:0016020	membrane

sp|P36225|MAP4_BOVIN
Microtubule-associated protein 4
Search

MAP4

0.59	Microtubule-associated protein 4

0.86	GO:1902856	negative regulation of non-motile cilium assembly
0.85	GO:0051012	microtubule sliding
0.80	GO:0051294	establishment of spindle orientation
0.78	GO:0007052	mitotic spindle organization
0.77	GO:0031175	neuron projection development
0.63	GO:0051301	cell division

0.74	GO:0008017	microtubule binding
0.55	GO:0003723	RNA binding
0.44	GO:0005198	structural molecule activity

0.78	GO:0014069	postsynaptic density
0.77	GO:0005930	axoneme
0.77	GO:0043005	neuron projection
0.76	GO:0072686	mitotic spindle
0.75	GO:0005875	microtubule associated complex
0.73	GO:0070062	extracellular exosome
0.72	GO:0005874	microtubule
0.52	GO:0005829	cytosol
0.45	GO:0005886	plasma membrane

sp|P37141|GPX3_BOVIN
Glutathione peroxidase 3
Search

0.47	Epididymal secretory glutathione peroxidase

0.71	GO:0006979	response to oxidative stress
0.69	GO:0098869	cellular oxidant detoxification
0.53	GO:0051289	protein homotetramerization
0.52	GO:0055114	oxidation-reduction process
0.45	GO:0042744	hydrogen peroxide catabolic process
0.43	GO:0033554	cellular response to stress
0.36	GO:0010269	response to selenium ion
0.36	GO:0051412	response to corticosterone
0.36	GO:0002238	response to molecule of fungal origin
0.34	GO:0006749	glutathione metabolic process

0.79	GO:0004602	glutathione peroxidase activity
0.53	GO:0008430	selenium binding
0.34	GO:0008134	transcription factor binding

0.54	GO:0005615	extracellular space
0.53	GO:0097524	sperm plasma membrane
0.37	GO:1903561	extracellular vesicle
0.30	GO:0016021	integral component of membrane

0.79

EC:1.11.1.9

GO:0004602

sp|P37289|PF2R_BOVIN
Prostaglandin F2-alpha receptor
Search

PTGFR

0.97	Ovarian prostaglandin F receptor

0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.63	GO:0071798	response to prostaglandin D
0.61	GO:0071379	cellular response to prostaglandin stimulus
0.60	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.59	GO:0032355	response to estradiol
0.58	GO:0032496	response to lipopolysaccharide
0.55	GO:0008284	positive regulation of cell proliferation
0.55	GO:0043066	negative regulation of apoptotic process
0.52	GO:0010628	positive regulation of gene expression
0.36	GO:0007567	parturition

0.85	GO:0004955	prostaglandin receptor activity
0.54	GO:0004960	thromboxane receptor activity
0.33	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

0.49	GO:0005576	extracellular region
0.44	GO:0005886	plasma membrane
0.40	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.33

GO:0016620

sp|P37359|MT3_BOVIN
Metallothionein-3
Search

MT3

0.76	Metallothionein

0.60	GO:0097214	positive regulation of lysosomal membrane permeability
0.60	GO:2000376	positive regulation of oxygen metabolic process
0.60	GO:0055073	cadmium ion homeostasis
0.59	GO:0071248	cellular response to metal ion
0.58	GO:0010940	positive regulation of necrotic cell death
0.58	GO:0060547	negative regulation of necrotic cell death
0.58	GO:0045926	negative regulation of growth
0.58	GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway
0.58	GO:0071732	cellular response to nitric oxide
0.57	GO:0036091	positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress

0.59	GO:0046870	cadmium ion binding
0.57	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.54	GO:0030295	protein kinase activator activity
0.50	GO:0008270	zinc ion binding
0.50	GO:0005507	copper ion binding
0.41	GO:0008144	drug binding
0.35	GO:0005515	protein binding
0.34	GO:0016209	antioxidant activity

0.56	GO:0048471	perinuclear region of cytoplasm
0.55	GO:0016234	inclusion body
0.54	GO:0008021	synaptic vesicle
0.43	GO:0097450	astrocyte end-foot
0.43	GO:0005634	nucleus
0.41	GO:0043197	dendritic spine
0.41	GO:0014069	postsynaptic density
0.41	GO:0005791	rough endoplasmic reticulum
0.40	GO:0030424	axon
0.40	GO:0005741	mitochondrial outer membrane

sp|P37980|IPYR_BOVIN
Inorganic pyrophosphatase
Search

PPA1

0.46	Inorganic pyrophosphatase

0.55	GO:0006796	phosphate-containing compound metabolic process
0.36	GO:0046907	intracellular transport
0.36	GO:0071344	diphosphate metabolic process
0.36	GO:0016192	vesicle-mediated transport
0.36	GO:0034613	cellular protein localization
0.35	GO:0015031	protein transport
0.35	GO:1901303	negative regulation of cargo loading into COPII-coated vesicle
0.34	GO:0007186	G-protein coupled receptor signaling pathway
0.34	GO:0051668	localization within membrane
0.34	GO:0016050	vesicle organization

0.78	GO:0004427	inorganic diphosphatase activity
0.64	GO:0000287	magnesium ion binding
0.35	GO:0032550	purine ribonucleoside binding
0.35	GO:0019001	guanyl nucleotide binding
0.35	GO:0004930	G-protein coupled receptor activity
0.34	GO:0001653	peptide receptor activity
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.49	GO:0005737	cytoplasm
0.38	GO:0070062	extracellular exosome
0.36	GO:0012505	endomembrane system
0.34	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0012506	vesicle membrane
0.34	GO:0048475	coated membrane
0.34	GO:0097708	intracellular vesicle
0.33	GO:0098805	whole membrane
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0031984	organelle subcompartment

0.78	EC:3.6.1.1	GO:0004427
0.78	KEGG:R00004	GO:0004427

sp|P38408|GNA14_BOVIN
Guanine nucleotide-binding protein subunit alpha-14
Search

GNA14

0.83	Guanine nucleotide binding protein q polypeptide

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.52	GO:0045634	regulation of melanocyte differentiation
0.51	GO:0007603	phototransduction, visible light
0.51	GO:0001508	action potential
0.50	GO:0009649	entrainment of circadian clock
0.49	GO:0048066	developmental pigmentation
0.49	GO:1905145	cellular response to acetylcholine
0.49	GO:1903831	signal transduction involved in cellular response to ammonium ion
0.49	GO:0042711	maternal behavior
0.48	GO:0021884	forebrain neuron development

0.81	GO:0031683	G-protein beta/gamma-subunit complex binding
0.80	GO:0001664	G-protein coupled receptor binding
0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.64	GO:0004871	signal transducer activity
0.44	GO:0005096	GTPase activator activity
0.37	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity
0.36	GO:0046872	metal ion binding
0.35	GO:0002046	opsin binding

0.50	GO:0001750	photoreceptor outer segment
0.49	GO:1905360	GTPase complex
0.49	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.46	GO:0030425	dendrite
0.46	GO:0044297	cell body
0.44	GO:0098797	plasma membrane protein complex
0.38	GO:0070062	extracellular exosome
0.37	GO:0031965	nuclear membrane
0.36	GO:0005765	lysosomal membrane
0.35	GO:0097232	lamellar body membrane

0.37

GO:0047391

sp|P38409|GNA11_BOVIN
Guanine nucleotide-binding protein subunit alpha-11
Search

0.78	Guanine nucleotide binding protein q polypeptide

0.69	GO:0007186	G-protein coupled receptor signaling pathway
0.55	GO:0007603	phototransduction, visible light
0.54	GO:0009649	entrainment of circadian clock
0.53	GO:1905145	cellular response to acetylcholine
0.53	GO:1903831	signal transduction involved in cellular response to ammonium ion
0.53	GO:0045634	regulation of melanocyte differentiation
0.52	GO:0001508	action potential
0.50	GO:0048066	developmental pigmentation
0.49	GO:0001501	skeletal system development
0.48	GO:0007507	heart development

0.79	GO:0031683	G-protein beta/gamma-subunit complex binding
0.78	GO:0001664	G-protein coupled receptor binding
0.66	GO:0003924	GTPase activity
0.64	GO:0005525	GTP binding
0.62	GO:0004871	signal transducer activity
0.42	GO:0005096	GTPase activator activity
0.41	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity
0.37	GO:0046872	metal ion binding

0.54	GO:0001750	photoreceptor outer segment
0.45	GO:1905360	GTPase complex
0.44	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.43	GO:0030425	dendrite
0.43	GO:0044297	cell body
0.40	GO:0098797	plasma membrane protein complex
0.39	GO:0005765	lysosomal membrane
0.39	GO:0031965	nuclear membrane
0.38	GO:0070062	extracellular exosome
0.35	GO:0005829	cytosol

0.41

GO:0047391

sp|P38447|NUCG_BOVIN
Endonuclease G, mitochondrial
Search

ENDOG

0.62	Mitochondrial endonuclease G

0.61	GO:0006309	apoptotic DNA fragmentation
0.57	GO:0034612	response to tumor necrosis factor
0.54	GO:0001701	in utero embryonic development
0.54	GO:0043065	positive regulation of apoptotic process
0.52	GO:0046677	response to antibiotic
0.45	GO:0036475	neuron death in response to oxidative stress
0.44	GO:1903626	positive regulation of DNA catabolic process
0.43	GO:1902510	regulation of apoptotic DNA fragmentation
0.43	GO:1901300	positive regulation of hydrogen peroxide-mediated programmed cell death
0.42	GO:0032355	response to estradiol

0.54	GO:0046872	metal ion binding
0.54	GO:0004519	endonuclease activity
0.51	GO:0003676	nucleic acid binding
0.39	GO:0004536	deoxyribonuclease activity
0.36	GO:0044540	L-cystine L-cysteine-lyase (deaminating)
0.36	GO:0080146	L-cysteine desulfhydrase activity
0.36	GO:0004123	cystathionine gamma-lyase activity
0.33	GO:0005515	protein binding
0.33	GO:0004867	serine-type endopeptidase inhibitor activity
0.33	GO:0004713	protein tyrosine kinase activity

0.45	GO:0005739	mitochondrion
0.42	GO:0043204	perikaryon
0.38	GO:0005829	cytosol
0.37	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.36	EC:4.4.1.1	GO:0044540
0.36	KEGG:R02408	GO:0044540

sp|P38572|UPK1A_BOVIN
Uroplakin-1a
Search

UPK1A

0.59	Cytochrome c oxidase, subunit VIb (Predicted)

0.64	GO:0030855	epithelial cell differentiation
0.49	GO:0007166	cell surface receptor signaling pathway
0.40	GO:0051259	protein oligomerization
0.37	GO:0034968	histone lysine methylation
0.34	GO:2001141	regulation of RNA biosynthetic process
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression

0.42	GO:0042803	protein homodimerization activity
0.37	GO:0018024	histone-lysine N-methyltransferase activity
0.36	GO:0008201	heparin binding
0.35	GO:0043565	sequence-specific DNA binding
0.35	GO:0046914	transition metal ion binding
0.35	GO:0003700	DNA binding transcription factor activity

0.62	GO:0016324	apical plasma membrane
0.60	GO:0009986	cell surface
0.46	GO:0005887	integral component of plasma membrane
0.41	GO:0005783	endoplasmic reticulum
0.37	GO:0005739	mitochondrion
0.37	GO:0070062	extracellular exosome
0.36	GO:0005634	nucleus

0.37

EC:2.1.1.43

GO:0018024

sp|P38573|UPK1B_BOVIN
Uroplakin-1b
Search

UPK1B

0.60	Tetraspanin

0.57	GO:0030855	epithelial cell differentiation
0.44	GO:0007166	cell surface receptor signaling pathway
0.36	GO:0034394	protein localization to cell surface

0.35	GO:0005515	protein binding
0.33	GO:0005198	structural molecule activity

0.58	GO:0016324	apical plasma membrane
0.42	GO:0005887	integral component of plasma membrane
0.37	GO:0070062	extracellular exosome
0.34	GO:0005783	endoplasmic reticulum

sp|P38574|UPK3A_BOVIN
Uroplakin-3a
Search

UPK3A

0.97	Uroplakin-3a isoform B

0.75	GO:0060157	urinary bladder development
0.73	GO:0055078	sodium ion homeostasis
0.70	GO:0055075	potassium ion homeostasis
0.69	GO:0015840	urea transport
0.69	GO:0006833	water transport
0.68	GO:0001822	kidney development
0.66	GO:0030855	epithelial cell differentiation
0.62	GO:0000902	cell morphogenesis
0.35	GO:0046325	negative regulation of glucose import
0.33	GO:0010629	negative regulation of gene expression

0.38	GO:0005515	protein binding
0.32	GO:0008270	zinc ion binding

0.67	GO:0016324	apical plasma membrane
0.41	GO:0005789	endoplasmic reticulum membrane
0.41	GO:0070062	extracellular exosome
0.35	GO:0005887	integral component of plasma membrane

sp|P38584|TTL_BOVIN
Tubulin--tyrosine ligase
Search

TTL

0.88	Tubulin--tyrosine ligase

0.62	GO:0018166	C-terminal protein-tyrosinylation
0.59	GO:0090235	regulation of metaphase plate congression
0.55	GO:0030516	regulation of axon extension
0.55	GO:0045931	positive regulation of mitotic cell cycle
0.51	GO:0000226	microtubule cytoskeleton organization

0.61	GO:0004835	tubulin-tyrosine ligase activity
0.40	GO:0032559	adenyl ribonucleotide binding
0.40	GO:0008144	drug binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding

0.34	GO:0005874	microtubule
0.34	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.61

EC:6.3.2.25

GO:0004835

sp|P38657|PDIA3_BOVIN
Protein disulfide-isomerase A3
Search

PDIA3

0.58	Protein disulfide-isomerase A3

0.69	GO:0045454	cell redox homeostasis
0.67	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway
0.64	GO:0034976	response to endoplasmic reticulum stress
0.54	GO:0006457	protein folding
0.52	GO:1904148	cellular response to nonylphenol
0.51	GO:1901423	response to benzene
0.51	GO:1903334	positive regulation of protein folding
0.50	GO:0033595	response to genistein
0.50	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.48	GO:0071305	cellular response to vitamin D

0.72	GO:0003756	protein disulfide isomerase activity
0.64	GO:0015037	peptide disulfide oxidoreductase activity
0.59	GO:0042802	identical protein binding
0.49	GO:0019153	protein-disulfide reductase (glutathione) activity
0.48	GO:0042288	MHC class I protein binding
0.46	GO:0004629	phospholipase C activity
0.44	GO:0004197	cysteine-type endopeptidase activity
0.43	GO:0003723	RNA binding

0.74	GO:0042470	melanosome
0.73	GO:0005788	endoplasmic reticulum lumen
0.64	GO:0043209	myelin sheath
0.63	GO:0009986	cell surface
0.58	GO:0005615	extracellular space
0.52	GO:0005925	focal adhesion
0.52	GO:1903561	extracellular vesicle
0.48	GO:0042825	TAP complex
0.48	GO:0005790	smooth endoplasmic reticulum
0.48	GO:0055038	recycling endosome membrane

0.72

EC:5.3.4.1

GO:0003756

sp|P39872|RL3_BOVIN
60S ribosomal protein L3
Search

RPL3

0.61	Ribosomal protein L3

0.59	GO:0043043	peptide biosynthetic process
0.54	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.51	GO:0009059	macromolecule biosynthetic process
0.50	GO:0071353	cellular response to interleukin-4
0.46	GO:0031017	exocrine pancreas development
0.43	GO:0000027	ribosomal large subunit assembly
0.35	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription

0.62	GO:0003735	structural constituent of ribosome
0.39	GO:0003723	RNA binding
0.33	GO:0005515	protein binding
0.32	GO:0016787	hydrolase activity

0.60	GO:0005840	ribosome
0.47	GO:0005730	nucleolus
0.46	GO:0005829	cytosol
0.41	GO:0043234	protein complex
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome

0.32

GO:0016787

sp|P39873|RNBR_BOVIN
Brain ribonuclease
Search

RNASE1

0.46	Pancreatic ribonuclease subtype Nb

0.64	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.44	GO:0016070	RNA metabolic process
0.36	GO:0051607	defense response to virus

0.66	GO:0004519	endonuclease activity
0.53	GO:0004540	ribonuclease activity
0.51	GO:0003676	nucleic acid binding
0.35	GO:0005515	protein binding

0.49	GO:0005576	extracellular region
0.34	GO:0031982	vesicle
0.30	GO:0031224	intrinsic component of membrane

sp|P39942|VATD_BOVIN
V-type proton ATPase subunit D
Search

ATP6V1D

0.86	V-type proton ATPase subunit D

0.55	GO:0055085	transmembrane transport
0.54	GO:0061512	protein localization to cilium
0.51	GO:0060271	cilium assembly
0.36	GO:0015992	proton transport
0.35	GO:0090383	phagosome acidification
0.35	GO:0033572	transferrin transport
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0008286	insulin receptor signaling pathway
0.35	GO:0016241	regulation of macroautophagy
0.34	GO:0042998	positive regulation of Golgi to plasma membrane protein transport

0.66	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.35	GO:0005515	protein binding
0.33	GO:0022853	active ion transmembrane transporter activity
0.33	GO:0015078	hydrogen ion transmembrane transporter activity

0.50	GO:0005813	centrosome
0.50	GO:0005929	cilium
0.49	GO:0033176	proton-transporting V-type ATPase complex
0.39	GO:0005765	lysosomal membrane
0.36	GO:0070062	extracellular exosome
0.35	GO:0035579	specific granule membrane
0.34	GO:0005802	trans-Golgi network
0.33	GO:0005829	cytosol
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P40293|CD79A_BOVIN
B-cell antigen receptor complex-associated protein alpha chain
Search

CD79A

0.97	B-cell antigen receptor complex-associated protein alpha chain

0.69	GO:0007166	cell surface receptor signaling pathway
0.67	GO:0051289	protein homotetramerization
0.65	GO:0030183	B cell differentiation
0.65	GO:0042100	B cell proliferation
0.63	GO:0002757	immune response-activating signal transduction
0.45	GO:0002250	adaptive immune response
0.37	GO:0035023	regulation of Rho protein signal transduction
0.35	GO:0065009	regulation of molecular function
0.34	GO:0006518	peptide metabolic process
0.34	GO:0043604	amide biosynthetic process

0.68	GO:0004888	transmembrane signaling receptor activity
0.60	GO:0042803	protein homodimerization activity
0.37	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.35	GO:0043565	sequence-specific DNA binding
0.34	GO:0003735	structural constituent of ribosome
0.33	GO:0046872	metal ion binding

0.70	GO:0019815	B cell receptor complex
0.64	GO:0005771	multivesicular body
0.63	GO:0009897	external side of plasma membrane
0.61	GO:0045121	membrane raft
0.46	GO:0005887	integral component of plasma membrane
0.34	GO:0005840	ribosome
0.34	GO:0005634	nucleus

sp|P40673|HMGB2_BOVIN
High mobility group protein B2
Search

HMGB2

0.82	High mobility group box 2

0.68	GO:0002437	inflammatory response to antigenic stimulus
0.64	GO:0050830	defense response to Gram-positive bacterium
0.63	GO:0050829	defense response to Gram-negative bacterium
0.62	GO:0032496	response to lipopolysaccharide
0.62	GO:0072091	regulation of stem cell proliferation
0.59	GO:0032392	DNA geometric change
0.58	GO:0050767	regulation of neurogenesis
0.56	GO:0043388	positive regulation of DNA binding
0.56	GO:0045654	positive regulation of megakaryocyte differentiation
0.56	GO:0001938	positive regulation of endothelial cell proliferation

0.74	GO:0008301	DNA binding, bending
0.71	GO:0000400	four-way junction DNA binding
0.71	GO:0097100	supercoiled DNA binding
0.62	GO:0001158	enhancer sequence-specific DNA binding
0.59	GO:0000405	bubble DNA binding
0.56	GO:0008134	transcription factor binding
0.56	GO:0050786	RAGE receptor binding
0.55	GO:0042056	chemoattractant activity
0.50	GO:0003684	damaged DNA binding
0.47	GO:0019904	protein domain specific binding

0.61	GO:0005634	nucleus
0.58	GO:0005615	extracellular space
0.55	GO:0000785	chromatin
0.52	GO:0000793	condensed chromosome
0.52	GO:0070013	intracellular organelle lumen
0.51	GO:0048471	perinuclear region of cytoplasm
0.44	GO:0043234	protein complex
0.40	GO:0017053	transcriptional repressor complex
0.39	GO:0009986	cell surface
0.38	GO:0005768	endosome

0.36

EC:4

GO:0016829

sp|P40682|VAS1_BOVIN
V-type proton ATPase subunit S1
Search

ATP6AP1

0.90	ATPase H+ transporting accessory protein 1

0.76	GO:0015991	ATP hydrolysis coupled proton transport
0.72	GO:2001206	positive regulation of osteoclast development
0.70	GO:0046852	positive regulation of bone remodeling
0.70	GO:0036295	cellular response to increased oxygen levels
0.69	GO:0045124	regulation of bone resorption
0.68	GO:0045669	positive regulation of osteoblast differentiation
0.67	GO:0045851	pH reduction
0.67	GO:0045921	positive regulation of exocytosis
0.66	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.65	GO:0032846	positive regulation of homeostatic process

0.81	GO:0046961	proton-transporting ATPase activity, rotational mechanism
0.72	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism
0.64	GO:0017137	Rab GTPase binding
0.39	GO:0005093	Rab GDP-dissociation inhibitor activity

0.81	GO:0033180	proton-transporting V-type ATPase, V1 domain
0.39	GO:0005886	plasma membrane
0.33	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|P41361|ANT3_BOVIN
Antithrombin-III
Search

SERPINC1

0.97	Serpin peptidase inhibitor clade C member 1

0.85	GO:2000266	regulation of blood coagulation, intrinsic pathway
0.74	GO:0010951	negative regulation of endopeptidase activity
0.45	GO:0071391	cellular response to estrogen stimulus
0.44	GO:0002438	acute inflammatory response to antigenic stimulus
0.43	GO:0007595	lactation
0.42	GO:0007584	response to nutrient
0.41	GO:0007596	blood coagulation
0.39	GO:0042129	regulation of T cell proliferation
0.37	GO:0010608	posttranscriptional regulation of gene expression
0.37	GO:0046628	positive regulation of insulin receptor signaling pathway

0.78	GO:0008201	heparin binding
0.76	GO:0004867	serine-type endopeptidase inhibitor activity
0.58	GO:0002020	protease binding
0.53	GO:0042802	identical protein binding
0.39	GO:0003730	mRNA 3'-UTR binding
0.34	GO:0046872	metal ion binding
0.34	GO:0035613	RNA stem-loop binding
0.33	GO:0016874	ligase activity
0.32	GO:0008233	peptidase activity

0.73	GO:0005615	extracellular space
0.41	GO:0060205	cytoplasmic vesicle lumen
0.39	GO:0043025	neuronal cell body
0.39	GO:0030141	secretory granule
0.38	GO:1903561	extracellular vesicle
0.35	GO:0005788	endoplasmic reticulum lumen
0.34	GO:0005886	plasma membrane
0.34	GO:0000932	P-body
0.34	GO:0010494	cytoplasmic stress granule

0.33

GO:0016874

sp|P41500|ACYP1_BOVIN
Acylphosphatase-1
Search

ACYP1

0.54	Acylphosphatase

0.36	GO:0007131	reciprocal meiotic recombination
0.36	GO:0006298	mismatch repair
0.33	GO:0007144	female meiosis I
0.33	GO:0007130	synaptonemal complex assembly
0.33	GO:0006796	phosphate-containing compound metabolic process
0.33	GO:0007140	male meiotic nuclear division
0.33	GO:0010469	regulation of receptor activity
0.32	GO:0008104	protein localization
0.32	GO:0036211	protein modification process
0.32	GO:0044267	cellular protein metabolic process

0.80	GO:0003998	acylphosphatase activity
0.35	GO:0030983	mismatched DNA binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0019237	centromeric DNA binding
0.33	GO:0008083	growth factor activity
0.33	GO:0003682	chromatin binding
0.32	GO:0016301	kinase activity
0.32	GO:0016773	phosphotransferase activity, alcohol group as acceptor

0.36	GO:0070062	extracellular exosome
0.36	GO:0032300	mismatch repair complex
0.33	GO:0005712	chiasma
0.33	GO:0001673	male germ cell nucleus
0.33	GO:0000795	synaptonemal complex
0.30	GO:0016020	membrane

0.80

EC:3.6.1.7

GO:0003998

sp|P41520|CCKN_BOVIN
Cholecystokinin
Search

CCK

0.97	Preprocholecystokinin

0.76	GO:0010469	regulation of receptor activity
0.60	GO:0042755	eating behavior
0.58	GO:0001764	neuron migration
0.56	GO:0007409	axonogenesis
0.44	GO:0031667	response to nutrient levels
0.42	GO:0014049	positive regulation of glutamate secretion
0.42	GO:0051901	positive regulation of mitochondrial depolarization
0.41	GO:0051930	regulation of sensory perception of pain
0.41	GO:0001836	release of cytochrome c from mitochondria
0.41	GO:0032096	negative regulation of response to food

0.79	GO:0005179	hormone activity
0.33	GO:0090729	toxin activity

0.66	GO:0005576	extracellular region
0.56	GO:0030424	axon
0.41	GO:0043204	perikaryon
0.40	GO:0043679	axon terminus
0.40	GO:0030425	dendrite
0.30	GO:0016021	integral component of membrane

sp|P41541|USO1_BOVIN
General vesicular transport factor p115
Search

USO1

0.92	USO1 vesicle transport factor

0.85	GO:0048280	vesicle fusion with Golgi apparatus
0.69	GO:0006886	intracellular protein transport
0.56	GO:0007030	Golgi organization
0.52	GO:0048211	Golgi vesicle docking
0.52	GO:0045056	transcytosis
0.48	GO:0006888	ER to Golgi vesicle-mediated transport

0.68	GO:0008565	protein transporter activity
0.58	GO:0045296	cadherin binding

0.74	GO:0000139	Golgi membrane
0.59	GO:0001650	fibrillar center
0.55	GO:0048471	perinuclear region of cytoplasm
0.49	GO:0005829	cytosol
0.48	GO:0012507	ER to Golgi transport vesicle membrane
0.48	GO:0005795	Golgi stack
0.45	GO:0005783	endoplasmic reticulum
0.36	GO:0070382	exocytic vesicle
0.30	GO:0031224	intrinsic component of membrane

sp|P41563|IDH3A_BOVIN
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial
Search

IDH3A

0.64	Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial

0.68	GO:0006099	tricarboxylic acid cycle
0.35	GO:0006734	NADH metabolic process
0.34	GO:0006103	2-oxoglutarate metabolic process
0.34	GO:0006102	isocitrate metabolic process
0.33	GO:0005975	carbohydrate metabolic process

0.82	GO:0004449	isocitrate dehydrogenase (NAD+) activity
0.67	GO:0051287	NAD binding
0.64	GO:0000287	magnesium ion binding

0.58	GO:0005739	mitochondrion
0.50	GO:0043209	myelin sheath
0.35	GO:0045242	isocitrate dehydrogenase complex (NAD+)
0.34	GO:0031974	membrane-enclosed lumen
0.34	GO:0005634	nucleus
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.82

EC:1.1.1.41

GO:0004449

sp|P41976|SODM_BOVIN
Superoxide dismutase [Mn], mitochondrial
Search

SOD2

0.46	Superoxide dismutase

0.75	GO:0071450	cellular response to oxygen radical
0.75	GO:0000303	response to superoxide
0.75	GO:0006801	superoxide metabolic process
0.69	GO:0098869	cellular oxidant detoxification
0.53	GO:0001306	age-dependent response to oxidative stress
0.52	GO:0055114	oxidation-reduction process
0.50	GO:0003070	regulation of systemic arterial blood pressure by neurotransmitter
0.49	GO:0048773	erythrophore differentiation
0.47	GO:0003085	negative regulation of systemic arterial blood pressure
0.47	GO:0001836	release of cytochrome c from mitochondria

0.77	GO:0004784	superoxide dismutase activity
0.54	GO:0046872	metal ion binding
0.37	GO:0042802	identical protein binding
0.37	GO:0019825	oxygen binding
0.36	GO:0019899	enzyme binding
0.34	GO:0003677	DNA binding

0.45	GO:0043209	myelin sheath
0.44	GO:0005759	mitochondrial matrix
0.39	GO:0031966	mitochondrial membrane
0.39	GO:0019866	organelle inner membrane
0.36	GO:0009295	nucleoid
0.36	GO:0070062	extracellular exosome
0.34	GO:0043232	intracellular non-membrane-bounded organelle

0.77

EC:1.15.1.1

GO:0004784

sp|P41984|ACM3_BOVIN
Muscarinic acetylcholine receptor M3
Search

CHRM3

0.81	Muscarinic acetylcholine receptor

0.84	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway
0.84	GO:0046541	saliva secretion
0.82	GO:0045987	positive regulation of smooth muscle contraction
0.52	GO:0001696	gastric acid secretion
0.51	GO:0003056	regulation of vascular smooth muscle contraction
0.50	GO:0007271	synaptic transmission, cholinergic
0.50	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.50	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.49	GO:0006939	smooth muscle contraction
0.46	GO:0015872	dopamine transport

0.85	GO:0016907	G-protein coupled acetylcholine receptor activity
0.46	GO:0042166	acetylcholine binding
0.35	GO:0005515	protein binding
0.35	GO:0004435	phosphatidylinositol phospholipase C activity
0.34	GO:0016934	extracellularly glycine-gated chloride channel activity
0.34	GO:0098772	molecular function regulator

0.79	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.66	GO:0005887	integral component of plasma membrane
0.43	GO:0016323	basolateral plasma membrane
0.41	GO:0043679	axon terminus
0.40	GO:0032279	asymmetric synapse
0.40	GO:0030425	dendrite

0.35	EC:3.1.4.11	GO:0004435
0.35	KEGG:R03435	GO:0004435

sp|P41985|ACM2_BOVIN
Muscarinic acetylcholine receptor M2
Search

CHRM2

0.81	Muscarinic acetylcholine receptor

0.85	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway
0.76	GO:0008016	regulation of heart contraction
0.54	GO:0040012	regulation of locomotion
0.53	GO:0009615	response to virus
0.49	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.48	GO:0007271	synaptic transmission, cholinergic
0.47	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.47	GO:0006940	regulation of smooth muscle contraction
0.40	GO:1903523	negative regulation of blood circulation
0.38	GO:0046541	saliva secretion

0.85	GO:0016907	G-protein coupled acetylcholine receptor activity
0.61	GO:1990763	arrestin family protein binding
0.34	GO:0008144	drug binding

0.79	GO:0045211	postsynaptic membrane
0.75	GO:0030054	cell junction
0.67	GO:0005887	integral component of plasma membrane
0.41	GO:0032280	symmetric synapse
0.39	GO:0043679	axon terminus
0.39	GO:0032279	asymmetric synapse
0.39	GO:0043025	neuronal cell body
0.39	GO:0030425	dendrite
0.35	GO:0030665	clathrin-coated vesicle membrane

sp|P41986|ACM4_BOVIN
Muscarinic acetylcholine receptor M4 (Fragment)
Search

ACM4

0.81	Acetylcholinergic receptor M4 (Fragment)

0.81	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway
0.73	GO:0040012	regulation of locomotion
0.36	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway

0.81

GO:0016907

G-protein coupled acetylcholine receptor activity

0.64

GO:0005887

integral component of plasma membrane

sp|P41987|CXA3_BOVIN
Gap junction alpha-3 protein
Search

GJA3

0.60	Gap junction protein (Fragment)

0.73	GO:0007601	visual perception
0.60	GO:0007154	cell communication
0.52	GO:0055085	transmembrane transport
0.46	GO:0048050	post-embryonic eye morphogenesis
0.46	GO:0031444	slow-twitch skeletal muscle fiber contraction
0.45	GO:0003161	cardiac conduction system development
0.44	GO:0055008	cardiac muscle tissue morphogenesis
0.43	GO:0008016	regulation of heart contraction
0.36	GO:0002088	lens development in camera-type eye
0.35	GO:0042542	response to hydrogen peroxide

0.82	GO:0005243	gap junction channel activity
0.34	GO:0042802	identical protein binding

0.84	GO:0005922	connexin complex
0.35	GO:0045121	membrane raft
0.33	GO:0005887	integral component of plasma membrane

sp|P42026|NDUS7_BOVIN
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial
Search

NDUFS7

0.90	NADH-ubiquinone oxidoreductase Fe-S protein 7 variant

0.53	GO:0032981	mitochondrial respiratory chain complex I assembly
0.52	GO:0055114	oxidation-reduction process
0.36	GO:0006325	chromatin organization
0.35	GO:0006281	DNA repair
0.33	GO:0016310	phosphorylation
0.33	GO:0046034	ATP metabolic process
0.33	GO:0006091	generation of precursor metabolites and energy
0.33	GO:0036211	protein modification process
0.32	GO:0044267	cellular protein metabolic process

0.71	GO:0048038	quinone binding
0.68	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.66	GO:0051539	4 iron, 4 sulfur cluster binding
0.52	GO:0046872	metal ion binding
0.39	GO:0002020	protease binding
0.37	GO:0031491	nucleosome binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding

0.52	GO:0005747	mitochondrial respiratory chain complex I
0.41	GO:0005886	plasma membrane
0.38	GO:0043025	neuronal cell body
0.38	GO:0043005	neuron projection
0.37	GO:0044456	synapse part
0.34	GO:0005634	nucleus
0.34	GO:0005759	mitochondrial matrix
0.30	GO:0016021	integral component of membrane

0.68

GO:0008137

sp|P42028|NDUS8_BOVIN
NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial
Search

NDUFS8

0.91	NADH dehydrogenase iron-sulfur protein 8, mitochondrial

0.53	GO:0032981	mitochondrial respiratory chain complex I assembly
0.52	GO:0055114	oxidation-reduction process
0.47	GO:0006979	response to oxidative stress
0.36	GO:0015991	ATP hydrolysis coupled proton transport
0.33	GO:0006119	oxidative phosphorylation

0.67	GO:0016651	oxidoreductase activity, acting on NAD(P)H
0.67	GO:0051539	4 iron, 4 sulfur cluster binding
0.36	GO:0046872	metal ion binding
0.35	GO:0015078	hydrogen ion transmembrane transporter activity
0.33	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

0.51	GO:0005747	mitochondrial respiratory chain complex I
0.37	GO:0033179	proton-transporting V-type ATPase, V0 domain
0.34	GO:0005759	mitochondrial matrix
0.34	GO:0044437	vacuolar part
0.30	GO:0016021	integral component of membrane

0.67

GO:0016651

sp|P42029|NDUA8_BOVIN
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8
Search

NDUFA8

0.91	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8

0.70	GO:0006120	mitochondrial electron transport, NADH to ubiquinone
0.59	GO:0032981	mitochondrial respiratory chain complex I assembly

0.52	GO:0032403	protein complex binding
0.34	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.32	GO:0003677	DNA binding
0.32	GO:0046872	metal ion binding

0.77	GO:0005747	mitochondrial respiratory chain complex I
0.56	GO:0005758	mitochondrial intermembrane space
0.33	GO:0005634	nucleus

0.34

GO:0008137

sp|P42201|LYAM3_BOVIN
P-selectin
Search

SELP

0.85	P-selectin

0.72	GO:0007155	cell adhesion
0.63	GO:0050900	leukocyte migration
0.54	GO:0033623	regulation of integrin activation
0.53	GO:0010572	positive regulation of platelet activation
0.53	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.52	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling
0.51	GO:0002687	positive regulation of leukocyte migration
0.49	GO:0006954	inflammatory response
0.45	GO:0033198	response to ATP
0.39	GO:0007202	activation of phospholipase C activity

0.63	GO:0030246	carbohydrate binding
0.56	GO:0033691	sialic acid binding
0.54	GO:0005509	calcium ion binding
0.51	GO:0048306	calcium-dependent protein binding
0.51	GO:0008201	heparin binding
0.50	GO:0001530	lipopolysaccharide binding
0.45	GO:0002020	protease binding
0.44	GO:0050839	cell adhesion molecule binding
0.39	GO:0043274	phospholipase binding
0.36	GO:0004888	transmembrane signaling receptor activity

0.54	GO:0009897	external side of plasma membrane
0.54	GO:0031092	platelet alpha granule membrane
0.50	GO:0005887	integral component of plasma membrane
0.48	GO:0005615	extracellular space
0.38	GO:0005901	caveola
0.38	GO:0005905	clathrin-coated pit
0.38	GO:0030863	cortical cytoskeleton
0.38	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0005634	nucleus

0.34

GO:0008081

sp|P42659|DPP6_BOVIN
Dipeptidyl aminopeptidase-like protein 6
Search

DPP6

0.92	Dipeptidyl peptidase like 6

0.58	GO:0006508	proteolysis
0.54	GO:1901379	regulation of potassium ion transmembrane transport
0.46	GO:0065009	regulation of molecular function
0.41	GO:0072659	protein localization to plasma membrane
0.37	GO:0019228	neuronal action potential
0.37	GO:0043268	positive regulation of potassium ion transport
0.37	GO:1904064	positive regulation of cation transmembrane transport
0.35	GO:1903078	positive regulation of protein localization to plasma membrane
0.35	GO:0048522	positive regulation of cellular process

0.64	GO:0017171	serine hydrolase activity
0.59	GO:0070011	peptidase activity, acting on L-amino acid peptides
0.55	GO:0015459	potassium channel regulator activity
0.34	GO:0005515	protein binding

0.51	GO:0008076	voltage-gated potassium channel complex
0.37	GO:0070062	extracellular exosome
0.35	GO:0043025	neuronal cell body
0.34	GO:0009986	cell surface

sp|P42891|ECE1_BOVIN
Endothelin-converting enzyme 1
Search

ECE1

0.76	Endothelin converting enzyme

0.85	GO:0016486	peptide hormone processing
0.57	GO:0010814	substance P catabolic process
0.57	GO:0010816	calcitonin catabolic process
0.56	GO:0010815	bradykinin catabolic process
0.55	GO:0001921	positive regulation of receptor recycling
0.54	GO:0060037	pharyngeal system development
0.54	GO:0002002	regulation of angiotensin levels in blood
0.53	GO:0042733	embryonic digit morphogenesis
0.51	GO:0043583	ear development
0.50	GO:0007507	heart development

0.70	GO:0004222	metalloendopeptidase activity
0.49	GO:0042803	protein homodimerization activity
0.44	GO:0008270	zinc ion binding
0.35	GO:0017046	peptide hormone binding
0.34	GO:0000339	RNA cap binding
0.33	GO:0003743	translation initiation factor activity

0.56	GO:0033093	Weibel-Palade body
0.51	GO:0009897	external side of plasma membrane
0.50	GO:0048471	perinuclear region of cytoplasm
0.49	GO:0005768	endosome
0.36	GO:0005765	lysosomal membrane
0.36	GO:0070062	extracellular exosome
0.36	GO:0044433	cytoplasmic vesicle part
0.35	GO:0012506	vesicle membrane
0.34	GO:0031300	intrinsic component of organelle membrane
0.34	GO:0005794	Golgi apparatus

0.70

GO:0004222

sp|P42899|RLA2_BOVIN
60S acidic ribosomal protein P2
Search

RPLP2

0.79	Renal carcinoma antigen NY-REN-44

0.69	GO:0006414	translational elongation
0.46	GO:0002181	cytoplasmic translation
0.38	GO:0043009	chordate embryonic development
0.36	GO:1904401	cellular response to Thyroid stimulating hormone
0.36	GO:0042254	ribosome biogenesis
0.35	GO:0071320	cellular response to cAMP
0.35	GO:0030218	erythrocyte differentiation
0.35	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0045727	positive regulation of translation
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane

0.63	GO:0003735	structural constituent of ribosome
0.34	GO:0043021	ribonucleoprotein complex binding
0.33	GO:0005515	protein binding
0.33	GO:0005506	iron ion binding

0.61	GO:0005840	ribosome
0.50	GO:0044445	cytosolic part
0.43	GO:0044446	intracellular organelle part
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

sp|P42916|CL43_BOVIN
Collectin-43
Search

SFTPD

0.94	Pulmonary surfactant-associated protein D

0.59	GO:1905226	regulation of adhesion of symbiont to host epithelial cell
0.57	GO:0043129	surfactant homeostasis
0.57	GO:0043152	induction of bacterial agglutination
0.57	GO:0052405	negative regulation by host of symbiont molecular function
0.56	GO:0048286	lung alveolus development
0.44	GO:0007585	respiratory gaseous exchange
0.43	GO:0008584	male gonad development
0.43	GO:0008585	female gonad development
0.42	GO:0045087	innate immune response
0.41	GO:0007155	cell adhesion

0.47	GO:0005201	extracellular matrix structural constituent
0.43	GO:0030246	carbohydrate binding
0.42	GO:0042302	structural constituent of cuticle
0.42	GO:0042802	identical protein binding
0.39	GO:0005178	integrin binding
0.36	GO:0030515	snoRNA binding
0.36	GO:0001530	lipopolysaccharide binding
0.36	GO:0033691	sialic acid binding
0.36	GO:0043274	phospholipase binding
0.35	GO:0004867	serine-type endopeptidase inhibitor activity

0.73	GO:0005581	collagen trimer
0.48	GO:0031012	extracellular matrix
0.42	GO:0005615	extracellular space
0.37	GO:0012505	endomembrane system
0.37	GO:0031410	cytoplasmic vesicle
0.36	GO:0005764	lysosome
0.35	GO:0005901	caveola
0.35	GO:0030863	cortical cytoskeleton
0.35	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0031984	organelle subcompartment

sp|P42917|INHBB_BOVIN
Inhibin beta B chain
Search

INHBB

0.95	Inhibin beta B subunit

0.75	GO:0010469	regulation of receptor activity
0.62	GO:0032686	negative regulation of hepatocyte growth factor production
0.62	GO:0048176	regulation of hepatocyte growth factor biosynthetic process
0.62	GO:0046882	negative regulation of follicle-stimulating hormone secretion
0.61	GO:0046881	positive regulation of follicle-stimulating hormone secretion
0.60	GO:0060279	positive regulation of ovulation
0.59	GO:0042036	negative regulation of cytokine biosynthetic process
0.59	GO:0032924	activin receptor signaling pathway
0.58	GO:0046676	negative regulation of insulin secretion
0.56	GO:0045444	fat cell differentiation

0.78	GO:0008083	growth factor activity
0.77	GO:0005179	hormone activity
0.52	GO:0042803	protein homodimerization activity
0.49	GO:0005160	transforming growth factor beta receptor binding
0.47	GO:0005125	cytokine activity
0.36	GO:0034711	inhibin binding
0.35	GO:0046982	protein heterodimerization activity
0.34	GO:0046812	host cell surface binding
0.33	GO:0003924	GTPase activity
0.33	GO:0005525	GTP binding

0.66	GO:0005576	extracellular region
0.54	GO:0048471	perinuclear region of cytoplasm
0.40	GO:0071944	cell periphery
0.33	GO:0043234	protein complex
0.30	GO:0016020	membrane

sp|P43033|LIS1_BOVIN
Platelet-activating factor acetylhydrolase IB subunit alpha
Search

PAFAH1B1

0.81	Platelet-activating factor acetylhydrolase IB subunit alpha

0.78	GO:0000132	establishment of mitotic spindle orientation
0.69	GO:0007399	nervous system development
0.67	GO:0051301	cell division
0.67	GO:0030154	cell differentiation
0.53	GO:0008090	retrograde axonal transport
0.51	GO:0090176	microtubule cytoskeleton organization involved in establishment of planar polarity
0.51	GO:0047496	vesicle transport along microtubule
0.51	GO:0051081	nuclear envelope disassembly
0.51	GO:0051661	maintenance of centrosome location
0.50	GO:0042249	establishment of planar polarity of embryonic epithelium

0.77	GO:0070840	dynein complex binding
0.48	GO:0051219	phosphoprotein binding
0.47	GO:0008017	microtubule binding
0.45	GO:0042803	protein homodimerization activity
0.41	GO:0016787	hydrolase activity
0.32	GO:0008168	methyltransferase activity
0.30	GO:0019899	enzyme binding
0.30	GO:0043167	ion binding
0.30	GO:1901681	sulfur compound binding
0.30	GO:0005539	glycosaminoglycan binding

0.73	GO:0005874	microtubule
0.70	GO:0005815	microtubule organizing center
0.70	GO:0005875	microtubule associated complex
0.51	GO:1904115	axon cytoplasm
0.49	GO:0005818	aster
0.49	GO:0032420	stereocilium
0.49	GO:0005635	nuclear envelope
0.48	GO:0000776	kinetochore
0.47	GO:0005938	cell cortex
0.47	GO:0031252	cell leading edge

0.41

GO:0016787

sp|P43249|GRK5_BOVIN
G protein-coupled receptor kinase 5
Search

GRK5

0.69	G protein-coupled receptor kinase

0.63	GO:0006468	protein phosphorylation
0.60	GO:0007165	signal transduction
0.54	GO:0008284	positive regulation of cell proliferation
0.53	GO:0043066	negative regulation of apoptotic process
0.51	GO:0051726	regulation of cell cycle
0.50	GO:0045444	fat cell differentiation
0.40	GO:0035469	determination of pancreatic left/right asymmetry
0.39	GO:1902017	regulation of cilium assembly
0.39	GO:0001947	heart looping
0.39	GO:0009966	regulation of signal transduction

0.85	GO:0004703	G-protein coupled receptor kinase activity
0.61	GO:0047696	beta-adrenergic receptor kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0008289	lipid binding
0.35	GO:0005080	protein kinase C binding

0.54	GO:0016607	nuclear speck
0.54	GO:0031965	nuclear membrane
0.48	GO:0005829	cytosol
0.43	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.85

GO:0004703

sp|P43480|IL10_BOVIN
Interleukin-10
Search

IL10

0.91	Interleukin-10

0.75	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.63	GO:0002904	positive regulation of B cell apoptotic process
0.62	GO:0032800	receptor biosynthetic process
0.62	GO:0002740	negative regulation of cytokine secretion involved in immune response
0.62	GO:0051045	negative regulation of membrane protein ectodomain proteolysis
0.61	GO:0030889	negative regulation of B cell proliferation
0.61	GO:0032715	negative regulation of interleukin-6 production
0.59	GO:0051384	response to glucocorticoid
0.59	GO:0050715	positive regulation of cytokine secretion

0.80	GO:0005125	cytokine activity
0.42	GO:0005141	interleukin-10 receptor binding
0.34	GO:0008083	growth factor activity

0.66

GO:0005576

extracellular region

sp|P43481|KIT_BOVIN
Mast/stem cell growth factor receptor Kit
Search

KIT

0.68	KIT proto-oncogene receptor tyrosine kinase

0.86	GO:0038109	Kit signaling pathway
0.85	GO:0038093	Fc receptor signaling pathway
0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.65	GO:0023014	signal transduction by protein phosphorylation
0.64	GO:0097326	melanocyte adhesion
0.64	GO:0002371	dendritic cell cytokine production
0.63	GO:0060374	mast cell differentiation
0.62	GO:0038162	erythropoietin-mediated signaling pathway
0.62	GO:0032762	mast cell cytokine production
0.62	GO:0097324	melanocyte migration

0.85	GO:0004716	signal transducer, downstream of receptor, with protein tyrosine kinase activity
0.82	GO:0019955	cytokine binding
0.80	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.57	GO:0002020	protease binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0046872	metal ion binding
0.52	GO:0042803	protein homodimerization activity

0.60	GO:0042629	mast cell granule
0.55	GO:0009897	external side of plasma membrane
0.53	GO:0005911	cell-cell junction
0.51	GO:0005615	extracellular space
0.40	GO:0001669	acrosomal vesicle
0.39	GO:0009898	cytoplasmic side of plasma membrane
0.33	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.85	EC:2.7.10	GO:0004716
0.36	KEGG:R04545	GO:0046934

sp|P43896|EFTS_BOVIN
Elongation factor Ts, mitochondrial
Search

TSFM

0.70	Elongation factor Ts, mitochondrial

0.70	GO:0006414	translational elongation
0.58	GO:0070129	regulation of mitochondrial translation
0.48	GO:0032543	mitochondrial translation
0.35	GO:0032784	regulation of DNA-templated transcription, elongation

0.70	GO:0003746	translation elongation factor activity
0.34	GO:0005515	protein binding

0.58	GO:0005739	mitochondrion
0.46	GO:0005634	nucleus
0.44	GO:0031974	membrane-enclosed lumen
0.40	GO:0044446	intracellular organelle part
0.32	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

sp|P45478|PPT1_BOVIN
Palmitoyl-protein thioesterase 1
Search

PPT1

0.84	Palmitoyl-protein thioesterase

0.84	GO:0002084	protein depalmitoylation
0.57	GO:0032429	regulation of phospholipase A2 activity
0.56	GO:0007625	grooming behavior
0.55	GO:0007040	lysosome organization
0.54	GO:0008306	associative learning
0.54	GO:0008344	adult locomotory behavior
0.53	GO:0099643	signal release from synapse
0.53	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.52	GO:0007601	visual perception
0.50	GO:0006836	neurotransmitter transport

0.83	GO:0008474	palmitoyl-(protein) hydrolase activity
0.43	GO:0016290	palmitoyl-CoA hydrolase activity
0.34	GO:0005515	protein binding

0.54	GO:0005764	lysosome
0.53	GO:0030424	axon
0.53	GO:0098793	presynapse
0.52	GO:0043025	neuronal cell body
0.52	GO:0030425	dendrite
0.49	GO:0005615	extracellular space
0.42	GO:0070382	exocytic vesicle
0.41	GO:0045121	membrane raft
0.39	GO:0005794	Golgi apparatus
0.39	GO:0005829	cytosol

0.83

EC:3.1.2.22

GO:0008474

sp|P45879|VDAC1_BOVIN
Voltage-dependent anion-selective channel protein 1
Search

VDAC1

0.94	Voltage-dependent anion-selective channel protein 1

0.69	GO:0098656	anion transmembrane transport
0.52	GO:0007270	neuron-neuron synaptic transmission
0.52	GO:0001662	behavioral fear response
0.51	GO:2000378	negative regulation of reactive oxygen species metabolic process
0.51	GO:1903146	regulation of autophagy of mitochondrion
0.50	GO:0007612	learning
0.49	GO:0006915	apoptotic process
0.49	GO:0030855	epithelial cell differentiation
0.39	GO:0006851	mitochondrial calcium ion transmembrane transport
0.34	GO:0016236	macroautophagy

0.78	GO:0008308	voltage-gated anion channel activity
0.51	GO:0044325	ion channel binding
0.48	GO:0019901	protein kinase binding
0.47	GO:0042802	identical protein binding
0.39	GO:0015288	porin activity
0.37	GO:0032403	protein complex binding
0.34	GO:1901265	nucleoside phosphate binding
0.34	GO:0005262	calcium channel activity
0.34	GO:0036094	small molecule binding

0.78	GO:0005741	mitochondrial outer membrane
0.54	GO:0005757	mitochondrial permeability transition pore complex
0.50	GO:0042645	mitochondrial nucleoid
0.49	GO:0043209	myelin sheath
0.42	GO:0019866	organelle inner membrane
0.40	GO:0005886	plasma membrane
0.40	GO:0045121	membrane raft
0.39	GO:0070382	exocytic vesicle
0.38	GO:0098793	presynapse
0.36	GO:0070062	extracellular exosome

sp|P46065|GUC1A_BOVIN
Guanylyl cyclase-activating protein 1
Search

GUCA1A

0.97	Guanylate cyclase activating protein 1

0.83	GO:0031284	positive regulation of guanylate cyclase activity
0.71	GO:0007601	visual perception
0.53	GO:0007602	phototransduction
0.40	GO:0071277	cellular response to calcium ion
0.36	GO:0022400	regulation of rhodopsin mediated signaling pathway

0.84	GO:0008048	calcium sensitive guanylate cyclase activator activity
0.70	GO:0005509	calcium ion binding
0.33	GO:0005515	protein binding

0.73	GO:0001750	photoreceptor outer segment
0.40	GO:0001917	photoreceptor inner segment
0.35	GO:0060170	ciliary membrane

sp|P46159|DEFB1_BOVIN
Beta-defensin 1
Search

0.80	Beta-defensin 1

0.87	GO:0060474	positive regulation of flagellated sperm motility involved in capacitation
0.86	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.84	GO:0050830	defense response to Gram-positive bacterium
0.84	GO:0019933	cAMP-mediated signaling
0.83	GO:0050829	defense response to Gram-negative bacterium

0.88	GO:0031731	CCR6 chemokine receptor binding
0.74	GO:0042802	identical protein binding

0.87	GO:1990742	microvesicle
0.86	GO:0097225	sperm midpiece
0.75	GO:0019898	extrinsic component of membrane
0.45	GO:0005622	intracellular

sp|P46160|DEFB2_BOVIN
Beta-defensin 2
Search

0.76	Enteric beta-defensin

0.77	GO:0042742	defense response to bacterium
0.40	GO:0031640	killing of cells of other organism
0.39	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.38	GO:0060474	positive regulation of flagellated sperm motility involved in capacitation
0.38	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.37	GO:0050832	defense response to fungus
0.37	GO:0019933	cAMP-mediated signaling
0.36	GO:0006935	chemotaxis

0.43	GO:0031731	CCR6 chemokine receptor binding
0.36	GO:0042802	identical protein binding

0.66	GO:0005576	extracellular region
0.38	GO:0031982	vesicle
0.37	GO:0097225	sperm midpiece
0.36	GO:0019898	extrinsic component of membrane
0.35	GO:0012505	endomembrane system
0.34	GO:0005622	intracellular

sp|P46161|DEFB3_BOVIN
Beta-defensin 3 (Fragment)
Search

0.65	Tracheal antimicrobial peptide

0.76	GO:0042742	defense response to bacterium
0.41	GO:0060474	positive regulation of flagellated sperm motility involved in capacitation
0.40	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.39	GO:0019933	cAMP-mediated signaling
0.39	GO:0031640	killing of cells of other organism
0.38	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.37	GO:0050832	defense response to fungus
0.36	GO:0006935	chemotaxis

0.44	GO:0031731	CCR6 chemokine receptor binding
0.38	GO:0042802	identical protein binding

0.66	GO:0005576	extracellular region
0.40	GO:0097225	sperm midpiece
0.39	GO:0031982	vesicle
0.38	GO:0019898	extrinsic component of membrane
0.34	GO:0012505	endomembrane system
0.34	GO:0005622	intracellular

sp|P46162|DEFB4_BOVIN
Beta-defensin 4
Search

0.63	Tracheal antimicrobial peptide

0.76	GO:0042742	defense response to bacterium
0.42	GO:0060474	positive regulation of flagellated sperm motility involved in capacitation
0.41	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.40	GO:0031640	killing of cells of other organism
0.40	GO:0019933	cAMP-mediated signaling
0.39	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.38	GO:0050832	defense response to fungus
0.36	GO:0006935	chemotaxis

0.45	GO:0031731	CCR6 chemokine receptor binding
0.38	GO:0042802	identical protein binding

0.66	GO:0005576	extracellular region
0.41	GO:0097225	sperm midpiece
0.39	GO:0031982	vesicle
0.39	GO:0019898	extrinsic component of membrane
0.34	GO:0005622	intracellular
0.34	GO:0012505	endomembrane system

sp|P46163|DEFB5_BOVIN
Beta-defensin 5
Search

0.62	Lingual antimicrobial peptide

0.76	GO:0042742	defense response to bacterium
0.42	GO:0060474	positive regulation of flagellated sperm motility involved in capacitation
0.41	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.40	GO:0019933	cAMP-mediated signaling
0.40	GO:0031640	killing of cells of other organism
0.39	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.38	GO:0050832	defense response to fungus
0.36	GO:0006935	chemotaxis

0.46	GO:0031731	CCR6 chemokine receptor binding
0.38	GO:0042802	identical protein binding

0.66	GO:0005576	extracellular region
0.41	GO:0097225	sperm midpiece
0.39	GO:0031982	vesicle
0.39	GO:0019898	extrinsic component of membrane
0.34	GO:0005622	intracellular
0.34	GO:0012505	endomembrane system

sp|P46164|DEFB6_BOVIN
Beta-defensin 6
Search

0.62	Tracheal antimicrobial peptide

0.77	GO:0042742	defense response to bacterium
0.40	GO:0031640	killing of cells of other organism
0.39	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.38	GO:0060474	positive regulation of flagellated sperm motility involved in capacitation
0.38	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.37	GO:0050832	defense response to fungus
0.37	GO:0019933	cAMP-mediated signaling
0.37	GO:0006935	chemotaxis

0.43	GO:0031731	CCR6 chemokine receptor binding
0.36	GO:0042802	identical protein binding

0.66	GO:0005576	extracellular region
0.38	GO:0042581	specific granule
0.38	GO:0097225	sperm midpiece
0.36	GO:0019898	extrinsic component of membrane

sp|P46165|DEFB7_BOVIN
Beta-defensin 7
Search

0.63	Tracheal antimicrobial peptide

0.76	GO:0042742	defense response to bacterium
0.42	GO:0060474	positive regulation of flagellated sperm motility involved in capacitation
0.41	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.40	GO:0019933	cAMP-mediated signaling
0.37	GO:0050832	defense response to fungus
0.37	GO:0031640	killing of cells of other organism

0.42	GO:0031731	CCR6 chemokine receptor binding
0.38	GO:0042802	identical protein binding

0.66	GO:0005576	extracellular region
0.41	GO:0097225	sperm midpiece
0.38	GO:0019898	extrinsic component of membrane
0.38	GO:0031982	vesicle
0.33	GO:0005622	intracellular

sp|P46166|DEFB8_BOVIN
Beta-defensin 8
Search

0.80	Neutrophil beta-defensin 4

0.78

GO:0042742

defense response to bacterium

0.66

GO:0005576

extracellular region

sp|P46167|DEFB9_BOVIN
Beta-defensin 9 (Fragment)
Search

0.64	Tracheal antimicrobial peptide

0.76	GO:0042742	defense response to bacterium
0.42	GO:0060474	positive regulation of flagellated sperm motility involved in capacitation
0.41	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.40	GO:0019933	cAMP-mediated signaling
0.38	GO:0031640	killing of cells of other organism
0.37	GO:0050832	defense response to fungus
0.36	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.34	GO:0006935	chemotaxis

0.43	GO:0031731	CCR6 chemokine receptor binding
0.38	GO:0042802	identical protein binding

0.66	GO:0005576	extracellular region
0.41	GO:0097225	sperm midpiece
0.38	GO:0019898	extrinsic component of membrane
0.38	GO:0031982	vesicle
0.33	GO:0005622	intracellular

sp|P46168|DFB10_BOVIN
Beta-defensin 10
Search

0.63	Tracheal antimicrobial peptide

0.76	GO:0042742	defense response to bacterium
0.43	GO:0060474	positive regulation of flagellated sperm motility involved in capacitation
0.42	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.41	GO:0019933	cAMP-mediated signaling
0.38	GO:0050832	defense response to fungus
0.37	GO:0031640	killing of cells of other organism

0.43	GO:0031731	CCR6 chemokine receptor binding
0.39	GO:0042802	identical protein binding

0.66	GO:0005576	extracellular region
0.42	GO:0097225	sperm midpiece
0.39	GO:0031982	vesicle
0.39	GO:0019898	extrinsic component of membrane
0.34	GO:0012505	endomembrane system
0.34	GO:0005622	intracellular

sp|P46169|DFB11_BOVIN
Beta-defensin 11
Search

0.62	Tracheal antimicrobial peptide

0.76	GO:0042742	defense response to bacterium
0.42	GO:0060474	positive regulation of flagellated sperm motility involved in capacitation
0.41	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.40	GO:0019933	cAMP-mediated signaling
0.38	GO:0050832	defense response to fungus
0.37	GO:0031640	killing of cells of other organism

0.42	GO:0031731	CCR6 chemokine receptor binding
0.38	GO:0042802	identical protein binding

0.66	GO:0005576	extracellular region
0.41	GO:0097225	sperm midpiece
0.40	GO:0031982	vesicle
0.39	GO:0019898	extrinsic component of membrane
0.35	GO:0012505	endomembrane system
0.34	GO:0005622	intracellular

sp|P46170|DFB12_BOVIN
Beta-defensin 12
Search

0.73	Beta-defensin 6

0.76	GO:0042742	defense response to bacterium
0.42	GO:0060474	positive regulation of flagellated sperm motility involved in capacitation
0.41	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.40	GO:0019933	cAMP-mediated signaling
0.39	GO:0031640	killing of cells of other organism
0.37	GO:0050832	defense response to fungus
0.37	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.35	GO:0006935	chemotaxis

0.44	GO:0031731	CCR6 chemokine receptor binding
0.39	GO:0042802	identical protein binding

0.66	GO:0005576	extracellular region
0.41	GO:0097225	sperm midpiece
0.41	GO:0031982	vesicle
0.39	GO:0019898	extrinsic component of membrane
0.36	GO:0012505	endomembrane system
0.34	GO:0044444	cytoplasmic part
0.34	GO:0043229	intracellular organelle

sp|P46171|DFB13_BOVIN
Beta-defensin 13
Search

0.61	Tracheal antimicrobial peptide

0.76	GO:0042742	defense response to bacterium
0.42	GO:0060474	positive regulation of flagellated sperm motility involved in capacitation
0.41	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.40	GO:0019933	cAMP-mediated signaling
0.39	GO:0031640	killing of cells of other organism
0.37	GO:0050832	defense response to fungus
0.37	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.35	GO:0006935	chemotaxis

0.44	GO:0031731	CCR6 chemokine receptor binding
0.38	GO:0042802	identical protein binding

0.66	GO:0005576	extracellular region
0.41	GO:0097225	sperm midpiece
0.41	GO:0031982	vesicle
0.39	GO:0019898	extrinsic component of membrane
0.36	GO:0012505	endomembrane system
0.34	GO:0005622	intracellular

sp|P46193|ANXA1_BOVIN
Annexin A1
Search

ANXA1

0.60

Annexin

0.72	GO:0043086	negative regulation of catalytic activity
0.62	GO:0045629	negative regulation of T-helper 2 cell differentiation
0.62	GO:0045627	positive regulation of T-helper 1 cell differentiation
0.60	GO:0002548	monocyte chemotaxis
0.60	GO:0045920	negative regulation of exocytosis
0.60	GO:0014839	myoblast migration involved in skeletal muscle regeneration
0.60	GO:0032743	positive regulation of interleukin-2 production
0.60	GO:0071385	cellular response to glucocorticoid stimulus
0.60	GO:0097350	neutrophil clearance
0.60	GO:0033031	positive regulation of neutrophil apoptotic process

0.85	GO:0004859	phospholipase inhibitor activity
0.81	GO:0005544	calcium-dependent phospholipid binding
0.70	GO:0005509	calcium ion binding
0.58	GO:0098641	cadherin binding involved in cell-cell adhesion
0.57	GO:0048306	calcium-dependent protein binding
0.54	GO:0030674	protein binding, bridging
0.45	GO:0005198	structural molecule activity
0.42	GO:0033676	double-stranded DNA-dependent ATPase activity
0.41	GO:0036310	annealing helicase activity
0.39	GO:0003727	single-stranded RNA binding

0.62	GO:0031232	extrinsic component of external side of plasma membrane
0.58	GO:0016328	lateral plasma membrane
0.57	GO:0001533	cornified envelope
0.56	GO:0070062	extracellular exosome
0.56	GO:0016324	apical plasma membrane
0.55	GO:0042383	sarcolemma
0.55	GO:0031514	motile cilium
0.55	GO:0005913	cell-cell adherens junction
0.55	GO:0005884	actin filament
0.54	GO:0005768	endosome

sp|P46194|CP19A_BOVIN
Aromatase
Search

CYP19A1

0.81

Aromatase

0.62	GO:2000866	positive regulation of estradiol secretion
0.61	GO:0006710	androgen catabolic process
0.61	GO:0002677	negative regulation of chronic inflammatory response
0.61	GO:0010760	negative regulation of macrophage chemotaxis
0.60	GO:0061370	testosterone biosynthetic process
0.60	GO:0060736	prostate gland growth
0.59	GO:0030540	female genitalia development
0.59	GO:0060065	uterus development
0.57	GO:0008585	female gonad development
0.55	GO:0030879	mammary gland development

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.65	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.34	GO:0019825	oxygen binding
0.33	GO:0009055	electron transfer activity

0.50	GO:0005783	endoplasmic reticulum
0.38	GO:0044297	cell body
0.38	GO:0043195	terminal bouton
0.37	GO:0030425	dendrite
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0044309	neuron spine
0.35	GO:0031984	organelle subcompartment
0.34	GO:0008021	synaptic vesicle
0.34	GO:0098794	postsynapse
0.33	GO:0005829	cytosol

0.68

EC:1.14

GO:0016705

sp|P46195|KGUA_BOVIN
Guanylate kinase
Search

GUK1

0.46	Guanylate kinase

0.77	GO:0046710	GDP metabolic process
0.74	GO:0046037	GMP metabolic process
0.50	GO:0016310	phosphorylation
0.41	GO:0006185	dGDP biosynthetic process
0.41	GO:0046054	dGMP metabolic process
0.40	GO:0034436	glycoprotein transport
0.40	GO:0046060	dATP metabolic process
0.39	GO:0009180	purine ribonucleoside diphosphate biosynthetic process
0.38	GO:0019673	GDP-mannose metabolic process
0.37	GO:1901070	guanosine-containing compound biosynthetic process

0.78	GO:0004385	guanylate kinase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.43	GO:0005829	cytosol
0.37	GO:0005922	connexin complex

0.78

EC:2.7.4.8

GO:0004385

sp|P46196|MK01_BOVIN
Mitogen-activated protein kinase 1
Search

MAPK1

0.58	Mitogen-activated protein kinase

0.80	GO:0000165	MAPK cascade
0.55	GO:0019858	cytosine metabolic process
0.55	GO:0060440	trachea formation
0.54	GO:0042473	outer ear morphogenesis
0.54	GO:0061308	cardiac neural crest cell development involved in heart development
0.54	GO:0060020	Bergmann glial cell differentiation
0.54	GO:1903351	cellular response to dopamine
0.54	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus
0.53	GO:0070849	response to epidermal growth factor
0.53	GO:1904355	positive regulation of telomere capping

0.82	GO:0004707	MAP kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0004708	MAP kinase kinase activity
0.52	GO:0001784	phosphotyrosine residue binding
0.51	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity
0.51	GO:0019902	phosphatase binding
0.47	GO:0042802	identical protein binding

0.53	GO:0031143	pseudopodium
0.48	GO:0005901	caveola
0.48	GO:0005829	cytosol
0.47	GO:0005925	focal adhesion
0.46	GO:0005770	late endosome
0.46	GO:0005769	early endosome
0.45	GO:0005634	nucleus
0.44	GO:0005739	mitochondrion
0.44	GO:0005794	Golgi apparatus
0.43	GO:0005856	cytoskeleton

0.82	EC:2.7.11.24	GO:0004707
0.82	KEGG:R00162	GO:0004707

sp|P46197|ANPRB_BOVIN
Atrial natriuretic peptide receptor 2
Search

NPR2

0.56	Guanylate cyclase

0.82	GO:0006182	cGMP biosynthetic process
0.64	GO:0007168	receptor guanylyl cyclase signaling pathway
0.63	GO:0006468	protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.61	GO:1900194	negative regulation of oocyte maturation
0.61	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus
0.57	GO:0051447	negative regulation of meiotic cell cycle
0.56	GO:0060348	bone development
0.50	GO:0022414	reproductive process
0.45	GO:0060038	cardiac muscle cell proliferation

0.82	GO:0004383	guanylate cyclase activity
0.66	GO:0016941	natriuretic peptide receptor activity
0.63	GO:0004672	protein kinase activity
0.62	GO:0017046	peptide hormone binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0042802	identical protein binding
0.46	GO:0004016	adenylate cyclase activity
0.35	GO:0019901	protein kinase binding

0.49	GO:0008074	guanylate cyclase complex, soluble
0.48	GO:0005887	integral component of plasma membrane
0.41	GO:0043235	receptor complex

0.82

EC:4.6.1.2

GO:0004383

sp|P46198|IF2M_BOVIN
Translation initiation factor IF-2, mitochondrial
Search

MTIF2

0.42	Mitochondrial translational initiation factor 2

0.70	GO:0006413	translational initiation
0.40	GO:0032790	ribosome disassembly
0.40	GO:0032543	mitochondrial translation
0.35	GO:0006446	regulation of translational initiation

0.71	GO:0003743	translation initiation factor activity
0.67	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0043024	ribosomal small subunit binding
0.33	GO:0003735	structural constituent of ribosome
0.32	GO:0000049	tRNA binding
0.32	GO:0046872	metal ion binding

0.50	GO:0005654	nucleoplasm
0.46	GO:0005739	mitochondrion
0.33	GO:0005840	ribosome

sp|P46200|MYB_BOVIN
Transcriptional activator Myb
Search

MYB

0.86	Transcriptional activator Myb

0.58	GO:0045624	positive regulation of T-helper cell differentiation
0.58	GO:0051574	positive regulation of histone H3-K9 methylation
0.57	GO:0051571	positive regulation of histone H3-K4 methylation
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.52	GO:0006338	chromatin remodeling
0.52	GO:0051254	positive regulation of RNA metabolic process
0.51	GO:0010557	positive regulation of macromolecule biosynthetic process
0.51	GO:0031328	positive regulation of cellular biosynthetic process

0.54	GO:0003677	DNA binding
0.53	GO:0001067	regulatory region nucleic acid binding
0.48	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting
0.44	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.40	GO:0071987	WD40-repeat domain binding

0.40	GO:0005634	nucleus
0.36	GO:0005829	cytosol
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part
0.33	GO:0042025	host cell nucleus
0.30	GO:0016020	membrane

sp|P46201|UTMP_BOVIN
Uterine milk protein
Search

SERPINA14

0.96	Uterine serpin (Fragment)

0.62	GO:0007565	female pregnancy
0.57	GO:0010951	negative regulation of endopeptidase activity

0.58

GO:0004867

serine-type endopeptidase inhibitor activity

0.73

GO:0005615

extracellular space

sp|P46282|IL12B_BOVIN
Interleukin-12 subunit beta
Search

IL12B

0.96	Interleukin-12 subunit beta

0.78	GO:0019221	cytokine-mediated signaling pathway
0.74	GO:0010469	regulation of receptor activity
0.64	GO:0010536	positive regulation of activation of Janus kinase activity
0.64	GO:0051140	regulation of NK T cell proliferation
0.64	GO:0032819	positive regulation of natural killer cell proliferation
0.64	GO:0051135	positive regulation of NK T cell activation
0.64	GO:0002857	positive regulation of natural killer cell mediated immune response to tumor cell
0.63	GO:0002858	regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
0.63	GO:0042104	positive regulation of activated T cell proliferation
0.63	GO:0032725	positive regulation of granulocyte macrophage colony-stimulating factor production

0.80	GO:0004896	cytokine receptor activity
0.79	GO:0005125	cytokine activity
0.66	GO:0042164	interleukin-12 alpha subunit binding
0.65	GO:0045519	interleukin-23 receptor binding
0.56	GO:0008083	growth factor activity
0.54	GO:0046982	protein heterodimerization activity
0.54	GO:0042802	identical protein binding
0.39	GO:0005143	interleukin-12 receptor binding

0.72	GO:0005615	extracellular space
0.46	GO:0043234	protein complex
0.40	GO:0005737	cytoplasm
0.36	GO:0097708	intracellular vesicle
0.35	GO:0012505	endomembrane system
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part
0.34	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016020	membrane

sp|P46411|EAA1_BOVIN
Excitatory amino acid transporter 1
Search

SLC1A3

0.45	Amino acid transporter

0.60	GO:0140016	D-aspartate import across plasma membrane
0.60	GO:0140009	L-aspartate import across plasma membrane
0.59	GO:0009449	gamma-aminobutyric acid biosynthetic process
0.59	GO:0098712	L-glutamate import across plasma membrane
0.58	GO:0031223	auditory behavior
0.56	GO:0021545	cranial nerve development
0.56	GO:0050885	neuromuscular process controlling balance
0.55	GO:0050806	positive regulation of synaptic transmission
0.54	GO:0007605	sensory perception of sound
0.53	GO:0048667	cell morphogenesis involved in neuron differentiation

0.72	GO:0015293	symporter activity
0.59	GO:0016595	glutamate binding
0.55	GO:0005313	L-glutamate transmembrane transporter activity
0.51	GO:0015081	sodium ion transmembrane transporter activity
0.48	GO:0022853	active ion transmembrane transporter activity
0.35	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.53	GO:0043025	neuronal cell body
0.52	GO:0043005	neuron projection
0.51	GO:0009986	cell surface
0.47	GO:0005887	integral component of plasma membrane
0.35	GO:0045111	intermediate filament cytoskeleton
0.35	GO:0016323	basolateral plasma membrane
0.34	GO:0098794	postsynapse
0.34	GO:0120038	plasma membrane bounded cell projection part
0.33	GO:0005794	Golgi apparatus
0.33	GO:0019866	organelle inner membrane

sp|P46446|ACY2_BOVIN
Aspartoacylase
Search

ASPA

0.89	Aspartoacylase

0.41	GO:0048714	positive regulation of oligodendrocyte differentiation
0.40	GO:0022010	central nervous system myelination
0.36	GO:0006533	aspartate catabolic process
0.34	GO:0006083	acetate metabolic process
0.33	GO:0006805	xenobiotic metabolic process
0.33	GO:0008652	cellular amino acid biosynthetic process
0.32	GO:0016032	viral process

0.67	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
0.61	GO:0016788	hydrolase activity, acting on ester bonds
0.52	GO:0046872	metal ion binding
0.51	GO:0042802	identical protein binding

0.48	GO:0005829	cytosol
0.39	GO:0016324	apical plasma membrane
0.39	GO:0005634	nucleus
0.38	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.67

EC:3.5.1

GO:0016811

sp|P46626|ADRB3_BOVIN
Beta-3 adrenergic receptor
Search

ADRB3

0.97	Beta-3 adrenergic receptor

0.85	GO:0071875	adrenergic receptor signaling pathway
0.83	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.68	GO:0002025	norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure
0.64	GO:0001659	temperature homeostasis
0.64	GO:0002024	diet induced thermogenesis
0.63	GO:0040015	negative regulation of multicellular organism growth
0.62	GO:0007190	activation of adenylate cyclase activity
0.60	GO:0050873	brown fat cell differentiation
0.60	GO:1902533	positive regulation of intracellular signal transduction
0.60	GO:0045823	positive regulation of heart contraction

0.85	GO:0004939	beta-adrenergic receptor activity
0.67	GO:0051380	norepinephrine binding
0.63	GO:0031690	adrenergic receptor binding
0.56	GO:0051379	epinephrine binding
0.54	GO:0042803	protein homodimerization activity
0.47	GO:0005057	signal transducer activity, downstream of receptor
0.47	GO:0030165	PDZ domain binding
0.47	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.44	GO:0046982	protein heterodimerization activity
0.36	GO:0050824	water binding

0.55	GO:0043235	receptor complex
0.54	GO:0005886	plasma membrane
0.48	GO:0005769	early endosome
0.37	GO:0005634	nucleus
0.35	GO:0045177	apical part of cell
0.34	GO:0098794	postsynapse
0.30	GO:0016021	integral component of membrane

0.35

EC:2.6.1

GO:0008483

sp|P47798|MSHR_BOVIN
Melanocyte-stimulating hormone receptor
Search

MC1R

0.69	Melanocyte-stimulating hormone receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.38	GO:0090037	positive regulation of protein kinase C signaling
0.38	GO:0010739	positive regulation of protein kinase A signaling
0.38	GO:0042438	melanin biosynthetic process
0.38	GO:0019233	sensory perception of pain
0.37	GO:0051897	positive regulation of protein kinase B signaling
0.37	GO:0043473	pigmentation
0.36	GO:0045944	positive regulation of transcription by RNA polymerase II
0.35	GO:0007017	microtubule-based process
0.35	GO:0007010	cytoskeleton organization

0.85	GO:0004980	melanocyte-stimulating hormone receptor activity
0.35	GO:0005200	structural constituent of cytoskeleton
0.34	GO:0003924	GTPase activity
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0019001	guanyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.55	GO:0005886	plasma membrane
0.35	GO:0005874	microtubule
0.30	GO:0016021	integral component of membrane

sp|P47803|RGR_BOVIN
RPE-retinal G protein-coupled receptor
Search

RGR

0.97	RPE-retinal G protein-coupled receptor

0.78	GO:0007602	phototransduction
0.77	GO:0007601	visual perception
0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.67	GO:0018298	protein-chromophore linkage
0.48	GO:0009584	detection of visible light

0.73	GO:0009881	photoreceptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.34	GO:0005515	protein binding

0.49

GO:0005887

integral component of plasma membrane

sp|P47865|AQP1_BOVIN
Aquaporin-1
Search

AQP1

0.89	Aquaporin 1, Colton blood group antigen

0.59	GO:0085018	maintenance of symbiont-containing vacuole by host
0.57	GO:0003097	renal water transport
0.57	GO:0072230	metanephric proximal straight tubule development
0.57	GO:0072232	metanephric proximal convoluted tubule segment 2 development
0.57	GO:0072220	metanephric descending thin limb development
0.56	GO:0021670	lateral ventricle development
0.56	GO:0051458	corticotropin secretion
0.55	GO:0072239	metanephric glomerulus vasculature development
0.55	GO:0044241	lipid digestion
0.55	GO:0055085	transmembrane transport

0.69	GO:0015267	channel activity
0.57	GO:0005372	water transmembrane transporter activity
0.54	GO:0035379	carbon dioxide transmembrane transporter activity
0.53	GO:0046875	ephrin receptor binding
0.49	GO:0015079	potassium ion transmembrane transporter activity
0.48	GO:0030184	nitric oxide transmembrane transporter activity
0.47	GO:0008519	ammonium transmembrane transporter activity
0.47	GO:0015168	glycerol transmembrane transporter activity
0.39	GO:0042802	identical protein binding

0.55	GO:0020003	symbiont-containing vacuole
0.55	GO:0009925	basal plasma membrane
0.54	GO:0005903	brush border
0.53	GO:0016324	apical plasma membrane
0.52	GO:0005901	caveola
0.51	GO:0070062	extracellular exosome
0.50	GO:0030424	axon
0.45	GO:0042383	sarcolemma
0.44	GO:0031253	cell projection membrane
0.43	GO:0031965	nuclear membrane

sp|P48018|SYT1_BOVIN
Synaptotagmin-1
Search

SYT1

0.88	Synaptotagmin Ia

0.82	GO:0099643	signal release from synapse
0.82	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.75	GO:0006836	neurotransmitter transport
0.72	GO:0001505	regulation of neurotransmitter levels
0.68	GO:0051649	establishment of localization in cell
0.62	GO:1903861	positive regulation of dendrite extension
0.59	GO:0017158	regulation of calcium ion-dependent exocytosis
0.57	GO:0017156	calcium ion regulated exocytosis
0.56	GO:0097479	synaptic vesicle localization
0.56	GO:0099003	vesicle-mediated transport in synapse

0.81	GO:0005544	calcium-dependent phospholipid binding
0.57	GO:0050750	low-density lipoprotein particle receptor binding
0.57	GO:0019905	syntaxin binding
0.55	GO:0048306	calcium-dependent protein binding
0.50	GO:0005509	calcium ion binding
0.49	GO:0030276	clathrin binding
0.47	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.41	GO:0001786	phosphatidylserine binding
0.40	GO:0005516	calmodulin binding
0.39	GO:0008022	protein C-terminus binding

0.81	GO:0008021	synaptic vesicle
0.59	GO:0099501	exocytic vesicle membrane
0.57	GO:0031045	dense core granule
0.55	GO:0042734	presynaptic membrane
0.52	GO:0030424	axon
0.48	GO:0005794	Golgi apparatus
0.48	GO:0005829	cytosol
0.45	GO:0042584	chromaffin granule membrane
0.41	GO:0030054	cell junction
0.40	GO:0060076	excitatory synapse

sp|P48034|AOXA_BOVIN
Aldehyde oxidase 1
Search

AOX1

0.52	Aldehyde oxidase

0.60	GO:0022900	electron transport chain
0.51	GO:0009115	xanthine catabolic process
0.44	GO:0017144	drug metabolic process
0.34	GO:0006805	xenobiotic metabolic process
0.33	GO:0072524	pyridine-containing compound metabolic process
0.33	GO:0006766	vitamin metabolic process

0.70	GO:0051537	2 iron, 2 sulfur cluster binding
0.67	GO:0051287	NAD binding
0.66	GO:0050660	flavin adenine dinucleotide binding
0.65	GO:0043546	molybdopterin cofactor binding
0.65	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors
0.62	GO:0005506	iron ion binding
0.61	GO:0009055	electron transfer activity
0.61	GO:0004031	aldehyde oxidase activity
0.51	GO:0042803	protein homodimerization activity
0.49	GO:0004854	xanthine dehydrogenase activity

0.50	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome

0.65

EC:1.1

GO:0016614

sp|P48035|FABP4_BOVIN
Fatty acid-binding protein, adipocyte
Search

FABP4

0.95	Adipocyte fatty acid-binding protein 4

0.76	GO:0050727	regulation of inflammatory response
0.65	GO:0050872	white fat cell differentiation
0.65	GO:0042632	cholesterol homeostasis
0.65	GO:0071285	cellular response to lithium ion
0.62	GO:0050873	brown fat cell differentiation
0.61	GO:0001816	cytokine production
0.60	GO:0071356	cellular response to tumor necrosis factor
0.59	GO:0032103	positive regulation of response to external stimulus
0.59	GO:0006469	negative regulation of protein kinase activity
0.59	GO:0031349	positive regulation of defense response

0.84	GO:0005504	fatty acid binding
0.43	GO:0008092	cytoskeletal protein binding

0.45	GO:0005615	extracellular space
0.40	GO:0043209	myelin sheath
0.40	GO:0005829	cytosol
0.39	GO:0005634	nucleus
0.38	GO:0005811	lipid droplet
0.38	GO:1903561	extracellular vesicle
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part

sp|P48042|P2RY1_BOVIN
P2Y purinoceptor 1
Search

P2RY1

0.97	Purinergic receptor P2Y, G-protein coupled 1

0.85	GO:0090075	relaxation of muscle
0.84	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway
0.82	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.80	GO:0030168	platelet activation
0.57	GO:0051050	positive regulation of transport
0.55	GO:0043269	regulation of ion transport
0.55	GO:0071407	cellular response to organic cyclic compound
0.45	GO:0097746	regulation of blood vessel diameter
0.44	GO:0051046	regulation of secretion
0.44	GO:0051240	positive regulation of multicellular organismal process

0.84	GO:0001608	G-protein coupled nucleotide receptor activity
0.83	GO:0001614	purinergic nucleotide receptor activity
0.43	GO:0045031	ATP-activated adenosine receptor activity
0.43	GO:0045032	ADP-activated adenosine receptor activity
0.43	GO:0031686	A1 adenosine receptor binding
0.40	GO:0097110	scaffold protein binding
0.38	GO:0043531	ADP binding
0.38	GO:0046982	protein heterodimerization activity
0.37	GO:0008528	G-protein coupled peptide receptor activity
0.37	GO:0004896	cytokine receptor activity

0.44	GO:0005886	plasma membrane
0.40	GO:0014069	postsynaptic density
0.39	GO:0044297	cell body
0.39	GO:0030425	dendrite
0.39	GO:0045177	apical part of cell
0.37	GO:0009986	cell surface
0.36	GO:0005739	mitochondrion
0.33	GO:0098552	side of membrane
0.31	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.33	EC:3.1.4.11	GO:0004435
0.33	KEGG:R03435	GO:0004435

sp|P48044|V2R_BOVIN
Vasopressin V2 receptor
Search

AVPR2

0.97	Arginine vasopressin receptor 2

0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.57	GO:0032609	interferon-gamma production
0.55	GO:0007249	I-kappaB kinase/NF-kappaB signaling
0.52	GO:0001992	regulation of systemic arterial blood pressure by vasopressin
0.52	GO:0034097	response to cytokine
0.49	GO:0045907	positive regulation of vasoconstriction
0.47	GO:1901652	response to peptide
0.45	GO:0032870	cellular response to hormone stimulus
0.42	GO:0035814	negative regulation of renal sodium excretion
0.42	GO:0035811	negative regulation of urine volume

0.85	GO:0005000	vasopressin receptor activity
0.46	GO:0042277	peptide binding
0.35	GO:0042562	hormone binding
0.34	GO:0005515	protein binding

0.48	GO:0005886	plasma membrane
0.37	GO:0005622	intracellular
0.35	GO:0031982	vesicle
0.34	GO:0012505	endomembrane system
0.34	GO:0098805	whole membrane
0.34	GO:0098588	bounding membrane of organelle
0.30	GO:0016021	integral component of membrane

sp|P48305|NDUB4_BOVIN
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4
Search

NDUFB4

0.93	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 pseudogene

0.53	GO:0055114	oxidation-reduction process
0.52	GO:0032981	mitochondrial respiratory chain complex I assembly
0.44	GO:0006979	response to oxidative stress
0.35	GO:0006119	oxidative phosphorylation

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.61	GO:0005739	mitochondrion
0.50	GO:0045271	respiratory chain complex I
0.46	GO:1990204	oxidoreductase complex
0.45	GO:0031965	nuclear membrane
0.43	GO:0019866	organelle inner membrane
0.39	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.69

GO:0008137

sp|P48427|TBCA_BOVIN
Tubulin-specific chaperone A
Search

TBCA

0.73	Tubulin-specific chaperone A

0.84	GO:0007021	tubulin complex assembly
0.84	GO:0007023	post-chaperonin tubulin folding pathway
0.38	GO:0007420	brain development
0.33	GO:0006886	intracellular protein transport
0.33	GO:0016192	vesicle-mediated transport
0.32	GO:0006413	translational initiation

0.84	GO:0048487	beta-tubulin binding
0.34	GO:0051087	chaperone binding
0.34	GO:0003723	RNA binding

0.73	GO:0005874	microtubule
0.49	GO:0005737	cytoplasm
0.46	GO:0005730	nucleolus
0.36	GO:0070062	extracellular exosome
0.33	GO:0048475	coated membrane
0.32	GO:0098796	membrane protein complex
0.30	GO:0016021	integral component of membrane

sp|P48452|PP2BA_BOVIN
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform
Search

PPP3CA

0.50	Serine/threonine-protein phosphatase

0.71	GO:0006470	protein dephosphorylation
0.57	GO:1905205	positive regulation of connective tissue replacement
0.56	GO:1903244	positive regulation of cardiac muscle hypertrophy in response to stress
0.56	GO:0033173	calcineurin-NFAT signaling cascade
0.55	GO:0051533	positive regulation of NFAT protein import into nucleus
0.55	GO:0014883	transition between fast and slow fiber
0.55	GO:0035562	negative regulation of chromatin binding
0.55	GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA
0.55	GO:0050774	negative regulation of dendrite morphogenesis
0.55	GO:0003299	muscle hypertrophy in response to stress

0.71	GO:0004721	phosphoprotein phosphatase activity
0.56	GO:0016018	cyclosporin A binding
0.51	GO:0005516	calmodulin binding
0.47	GO:0019899	enzyme binding
0.46	GO:0046983	protein dimerization activity
0.34	GO:0046872	metal ion binding

0.56	GO:0005955	calcineurin complex
0.52	GO:0030018	Z disc
0.49	GO:0098794	postsynapse
0.47	GO:0005654	nucleoplasm
0.47	GO:0005829	cytosol
0.43	GO:0005739	mitochondrion
0.39	GO:0042383	sarcolemma
0.30	GO:0016021	integral component of membrane

0.71

EC:3.1.3.16

GO:0004721

sp|P48616|VIME_BOVIN
Vimentin
Search

VIM

0.86	Putative nuclear envelope protein lamin intermediate filament superfamily

0.59	GO:0060020	Bergmann glial cell differentiation
0.58	GO:0070307	lens fiber cell development
0.58	GO:0010714	positive regulation of collagen metabolic process
0.58	GO:0032965	regulation of collagen biosynthetic process
0.58	GO:0014002	astrocyte development
0.57	GO:0045109	intermediate filament organization
0.56	GO:0060395	SMAD protein signal transduction
0.56	GO:0071346	cellular response to interferon-gamma
0.56	GO:0010977	negative regulation of neuron projection development
0.56	GO:0043488	regulation of mRNA stability

0.62	GO:0005198	structural molecule activity
0.60	GO:1990254	keratin filament binding
0.57	GO:0097110	scaffold protein binding
0.55	GO:0008022	protein C-terminus binding
0.52	GO:0019904	protein domain specific binding
0.52	GO:0003725	double-stranded RNA binding
0.51	GO:0042802	identical protein binding
0.35	GO:0051721	protein phosphatase 2A binding
0.34	GO:0019901	protein kinase binding

0.79	GO:0005882	intermediate filament
0.55	GO:0045335	phagocytic vesicle
0.55	GO:0005844	polysome
0.54	GO:0031252	cell leading edge
0.52	GO:0043005	neuron projection
0.52	GO:0005777	peroxisome
0.48	GO:0005829	cytosol
0.42	GO:0005886	plasma membrane
0.37	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion

sp|P48617|EPO_BOVIN
Erythropoietin
Search

EPO

0.97	Erythropoietin

0.83	GO:0043249	erythrocyte maturation
0.76	GO:0010469	regulation of receptor activity
0.75	GO:0038162	erythropoietin-mediated signaling pathway
0.72	GO:1902250	regulation of erythrocyte apoptotic process
0.70	GO:1902219	negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress
0.69	GO:0033033	negative regulation of myeloid cell apoptotic process
0.68	GO:0042541	hemoglobin biosynthetic process
0.67	GO:0010523	negative regulation of calcium ion transport into cytosol
0.67	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein
0.66	GO:2001258	negative regulation of cation channel activity

0.87	GO:0005128	erythropoietin receptor binding
0.79	GO:0005179	hormone activity
0.63	GO:0030295	protein kinase activator activity
0.62	GO:0005125	cytokine activity

0.66	GO:0005576	extracellular region
0.59	GO:0009986	cell surface
0.44	GO:0044297	cell body
0.30	GO:0016020	membrane

sp|P48644|AL1A1_BOVIN
Retinal dehydrogenase 1
Search

ALDH1A1

0.38	Aldehyde dehydrogenase

0.53	GO:0055114	oxidation-reduction process
0.48	GO:0001523	retinoid metabolic process
0.45	GO:0034754	cellular hormone metabolic process
0.45	GO:0034308	primary alcohol metabolic process
0.43	GO:0002072	optic cup morphogenesis involved in camera-type eye development
0.42	GO:0006081	cellular aldehyde metabolic process
0.42	GO:0016102	diterpenoid biosynthetic process
0.41	GO:0051289	protein homotetramerization
0.40	GO:0021768	nucleus accumbens development
0.40	GO:0043065	positive regulation of apoptotic process

0.69	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.41	GO:0051287	NAD binding
0.40	GO:0042562	hormone binding
0.38	GO:0042802	identical protein binding
0.36	GO:0046983	protein dimerization activity
0.34	GO:0005096	GTPase activator activity
0.34	GO:0043168	anion binding
0.32	GO:0046872	metal ion binding

0.49	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.36	GO:0005634	nucleus
0.34	GO:0005886	plasma membrane

0.69

GO:0016620

sp|P48733|UROM_BOVIN
Uromodulin
Search

UMOD

0.93	Pancreatic zymogen granule membrane protein GP-2

0.62	GO:0072233	metanephric thick ascending limb development
0.61	GO:0072221	metanephric distal convoluted tubule development
0.61	GO:0072218	metanephric ascending thin limb development
0.59	GO:0007588	excretion
0.58	GO:0007159	leukocyte cell-cell adhesion
0.58	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.58	GO:1990266	neutrophil migration
0.56	GO:2000021	regulation of ion homeostasis
0.51	GO:0048878	chemical homeostasis
0.38	GO:0002412	antigen transcytosis by M cells in mucosal-associated lymphoid tissue

0.62	GO:0005509	calcium ion binding
0.61	GO:0019864	IgG binding
0.36	GO:0003823	antigen binding
0.36	GO:0004930	G-protein coupled receptor activity
0.36	GO:0005201	extracellular matrix structural constituent
0.34	GO:0051537	2 iron, 2 sulfur cluster binding
0.33	GO:0008061	chitin binding
0.32	GO:0035374	chondroitin sulfate binding
0.32	GO:0050431	transforming growth factor beta binding
0.32	GO:0003682	chromatin binding

0.64	GO:0005576	extracellular region
0.57	GO:0016324	apical plasma membrane
0.57	GO:0016323	basolateral plasma membrane
0.56	GO:0031225	anchored component of membrane
0.55	GO:0000922	spindle pole
0.54	GO:0005929	cilium
0.44	GO:0031253	cell projection membrane
0.41	GO:0098588	bounding membrane of organelle
0.38	GO:0031982	vesicle
0.37	GO:0005796	Golgi lumen

0.32

EC:1.14.17

GO:0016715

sp|P48734|CDK1_BOVIN
Cyclin-dependent kinase 1
Search

CDK1

0.87	LOW QUALITY PROTEIN: cyclin-dependent kinase 1

0.63	GO:0006468	protein phosphorylation
0.55	GO:1905448	positive regulation of mitochondrial ATP synthesis coupled electron transport
0.53	GO:0044772	mitotic cell cycle phase transition
0.53	GO:0051726	regulation of cell cycle
0.52	GO:0034501	protein localization to kinetochore
0.52	GO:0018210	peptidyl-threonine modification
0.51	GO:1900182	positive regulation of protein localization to nucleus
0.51	GO:0018209	peptidyl-serine modification
0.50	GO:0016570	histone modification
0.50	GO:0030855	epithelial cell differentiation

0.66	GO:0004674	protein serine/threonine kinase activity
0.57	GO:0097472	cyclin-dependent protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.53	GO:0035173	histone kinase activity
0.52	GO:0030544	Hsp70 protein binding
0.51	GO:0030332	cyclin binding
0.48	GO:0003682	chromatin binding

0.56	GO:0097125	cyclin B1-CDK1 complex
0.53	GO:0072686	mitotic spindle
0.51	GO:0030496	midbody
0.51	GO:0005876	spindle microtubule
0.51	GO:0005815	microtubule organizing center
0.48	GO:0005759	mitochondrial matrix
0.46	GO:0005829	cytosol
0.46	GO:0005634	nucleus
0.36	GO:0070062	extracellular exosome
0.36	GO:0000781	chromosome, telomeric region

0.66

GO:0004674

sp|P48765|NAC1_BOVIN
Sodium/calcium exchanger 1
Search

SLC8A1

0.84	Solute carrier family 8 sodium/calcium exchanger member 1 splicing variant 1.41

0.77	GO:0035725	sodium ion transmembrane transport
0.76	GO:0006816	calcium ion transport
0.66	GO:0098735	positive regulation of the force of heart contraction
0.65	GO:0006883	cellular sodium ion homeostasis
0.64	GO:0035994	response to muscle stretch
0.63	GO:0030501	positive regulation of bone mineralization
0.60	GO:0007154	cell communication
0.40	GO:0045214	sarcomere organization
0.39	GO:0006874	cellular calcium ion homeostasis

0.85	GO:0005432	calcium:sodium antiporter activity
0.64	GO:0030506	ankyrin binding

0.53	GO:0005654	nucleoplasm
0.51	GO:0005887	integral component of plasma membrane

sp|P48803|FGF4_BOVIN
Fibroblast growth factor 4
Search

FGF4

0.62	Fibroblast growth factor

0.79	GO:0008543	fibroblast growth factor receptor signaling pathway
0.76	GO:0010469	regulation of receptor activity
0.60	GO:0001502	cartilage condensation
0.56	GO:0008284	positive regulation of cell proliferation
0.56	GO:0060591	chondroblast differentiation
0.56	GO:2000544	regulation of endothelial cell chemotaxis to fibroblast growth factor
0.55	GO:0010463	mesenchymal cell proliferation
0.54	GO:0060363	cranial suture morphogenesis
0.53	GO:0060561	apoptotic process involved in morphogenesis
0.53	GO:0035116	embryonic hindlimb morphogenesis

0.81	GO:0005104	fibroblast growth factor receptor binding
0.78	GO:0008083	growth factor activity
0.37	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.36	GO:0016303	1-phosphatidylinositol-3-kinase activity
0.36	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.36	GO:0004713	protein tyrosine kinase activity
0.35	GO:0008201	heparin binding

0.63	GO:0005576	extracellular region
0.36	GO:0042383	sarcolemma
0.32	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

0.37	EC:2.7.1.153	GO:0046934
0.37	KEGG:R04545	GO:0046934

sp|P48818|ACADV_BOVIN
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial
Search

ACADVL

0.95	Very-long-chain acyl-CoA dehydrogenase

0.56	GO:0046322	negative regulation of fatty acid oxidation
0.55	GO:0090181	regulation of cholesterol metabolic process
0.55	GO:0001659	temperature homeostasis
0.53	GO:0045717	negative regulation of fatty acid biosynthetic process
0.53	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase
0.52	GO:0030855	epithelial cell differentiation
0.52	GO:0009409	response to cold
0.43	GO:0060322	head development
0.36	GO:0036498	IRE1-mediated unfolded protein response
0.35	GO:0042760	very long-chain fatty acid catabolic process

0.74	GO:0003995	acyl-CoA dehydrogenase activity
0.66	GO:0050660	flavin adenine dinucleotide binding
0.35	GO:0000062	fatty-acyl-CoA binding
0.33	GO:0008289	lipid binding

0.53	GO:0042645	mitochondrial nucleoid
0.49	GO:0005730	nucleolus
0.47	GO:0005829	cytosol
0.44	GO:0031966	mitochondrial membrane
0.36	GO:0019866	organelle inner membrane
0.34	GO:0036128	CatSper complex

0.74

EC:1.3.99.3

GO:0003995

sp|P48820|RBP2_BOVIN
E3 SUMO-protein ligase RanBP2 (Fragment)
Search

0.55	RAN-binding protein 2 (Fragment)

0.70	GO:0000413	protein peptidyl-prolyl isomerization
0.67	GO:0046907	intracellular transport
0.54	GO:0006457	protein folding
0.43	GO:0090526	regulation of gluconeogenesis involved in cellular glucose homeostasis
0.43	GO:0033133	positive regulation of glucokinase activity
0.42	GO:0051642	centrosome localization
0.42	GO:0006607	NLS-bearing protein import into nucleus
0.41	GO:0016925	protein sumoylation
0.36	GO:0046604	positive regulation of mitotic centrosome separation
0.35	GO:0000082	G1/S transition of mitotic cell cycle

0.70	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.49	GO:0046872	metal ion binding
0.41	GO:0016874	ligase activity
0.40	GO:0008536	Ran GTPase binding
0.34	GO:0005096	GTPase activator activity
0.30	GO:1901363	heterocyclic compound binding
0.30	GO:0097159	organic cyclic compound binding

0.44	GO:0005622	intracellular
0.43	GO:0005642	annulate lamellae
0.37	GO:0031090	organelle membrane
0.36	GO:0031975	envelope
0.36	GO:0043234	protein complex
0.33	GO:0043228	non-membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

0.70

GO:0003755

sp|P48830|ZP3_BOVIN
Zona pellucida sperm-binding protein 3
Search

ZP3

0.91	Zona pellucida protein subunit C

0.65	GO:0001809	positive regulation of type IV hypersensitivity
0.65	GO:2000387	regulation of antral ovarian follicle growth
0.65	GO:2000386	positive regulation of ovarian follicle development
0.64	GO:0035803	egg coat formation
0.63	GO:2000344	positive regulation of acrosome reaction
0.62	GO:0010513	positive regulation of phosphatidylinositol biosynthetic process
0.61	GO:0007339	binding of sperm to zona pellucida
0.61	GO:0032753	positive regulation of interleukin-4 production
0.61	GO:0001825	blastocyst formation
0.60	GO:0090280	positive regulation of calcium ion import

0.56	GO:0035804	structural constituent of egg coat
0.54	GO:0048018	receptor ligand activity
0.53	GO:0032190	acrosin binding
0.46	GO:0030246	carbohydrate binding
0.40	GO:0042802	identical protein binding

0.64	GO:0005576	extracellular region
0.46	GO:0045177	apical part of cell
0.44	GO:0005886	plasma membrane
0.38	GO:0005622	intracellular
0.35	GO:0043234	protein complex
0.34	GO:0035805	egg coat
0.30	GO:0016021	integral component of membrane

sp|P49004|DPOD2_BOVIN
DNA polymerase delta subunit 2
Search

POLD2

0.90	LOW QUALITY PROTEIN: DNA polymerase delta subunit 2

0.64	GO:0071897	DNA biosynthetic process
0.63	GO:0006260	DNA replication
0.47	GO:0022616	DNA strand elongation
0.42	GO:0006974	cellular response to DNA damage stimulus
0.35	GO:0000723	telomere maintenance
0.34	GO:0006266	DNA ligation
0.34	GO:0051606	detection of stimulus
0.34	GO:0022402	cell cycle process
0.34	GO:0019725	cellular homeostasis
0.33	GO:0090305	nucleic acid phosphodiester bond hydrolysis

0.67	GO:0003887	DNA-directed DNA polymerase activity
0.53	GO:0003677	DNA binding
0.33	GO:0005515	protein binding

0.50	GO:0043625	delta DNA polymerase complex
0.49	GO:0005654	nucleoplasm
0.32	GO:0030532	small nuclear ribonucleoprotein complex
0.30	GO:0031224	intrinsic component of membrane

0.67

GO:0003887

sp|P49220|UR2R_BOVIN
Urotensin-2 receptor
Search

UTS2R

0.97	Urotensin II receptor

0.82	GO:0008217	regulation of blood pressure
0.82	GO:0097746	regulation of blood vessel diameter
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.42	GO:0046005	positive regulation of circadian sleep/wake cycle, REM sleep
0.42	GO:0035814	negative regulation of renal sodium excretion
0.41	GO:0035811	negative regulation of urine volume
0.41	GO:0010841	positive regulation of circadian sleep/wake cycle, wakefulness
0.40	GO:0048146	positive regulation of fibroblast proliferation
0.40	GO:1903524	positive regulation of blood circulation
0.40	GO:0045766	positive regulation of angiogenesis

0.86

GO:0001604

urotensin II receptor activity

0.43	GO:0005887	integral component of plasma membrane
0.39	GO:0055037	recycling endosome
0.39	GO:0005769	early endosome
0.33	GO:0005681	spliceosomal complex

sp|P49259|PLA2R_BOVIN
Secretory phospholipase A2 receptor
Search

PLA2R1

0.94	Secretory phospholipase A2 receptor

0.73	GO:0090238	positive regulation of arachidonic acid secretion
0.72	GO:0090403	oxidative stress-induced premature senescence
0.71	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator
0.70	GO:0090399	replicative senescence
0.67	GO:0001816	cytokine production
0.59	GO:0072593	reactive oxygen species metabolic process
0.58	GO:0006898	receptor-mediated endocytosis
0.46	GO:1900139	negative regulation of arachidonic acid secretion
0.45	GO:1900138	negative regulation of phospholipase A2 activity
0.44	GO:0007165	signal transduction

0.71	GO:0043274	phospholipase binding
0.50	GO:0004872	receptor activity
0.45	GO:0004871	signal transducer activity
0.44	GO:0030246	carbohydrate binding

0.61	GO:0043235	receptor complex
0.59	GO:0009986	cell surface
0.48	GO:0005886	plasma membrane
0.44	GO:0005576	extracellular region
0.39	GO:0031982	vesicle
0.30	GO:0016021	integral component of membrane

sp|P49355|FNTB_BOVIN
Protein farnesyltransferase subunit beta
Search

0.87	CHURC1-FNTB readthrough

0.85	GO:0018343	protein farnesylation
0.76	GO:0042127	regulation of cell proliferation
0.60	GO:0042060	wound healing
0.57	GO:0048522	positive regulation of cellular process
0.55	GO:0010557	positive regulation of macromolecule biosynthetic process
0.55	GO:0010628	positive regulation of gene expression
0.54	GO:0051173	positive regulation of nitrogen compound metabolic process
0.54	GO:0007275	multicellular organism development
0.52	GO:0048523	negative regulation of cellular process
0.46	GO:1903506	regulation of nucleic acid-templated transcription

0.61	GO:0004659	prenyltransferase activity
0.50	GO:0008270	zinc ion binding
0.43	GO:0140096	catalytic activity, acting on a protein

0.85

GO:0005965

protein farnesyltransferase complex

0.61

EC:2.5.1

GO:0004659

sp|P49410|EFTU_BOVIN
Elongation factor Tu, mitochondrial
Search

TUFM

0.44	Tu translation elongation factor, mitochondrial

0.69	GO:0006414	translational elongation
0.38	GO:0045471	response to ethanol
0.38	GO:0032543	mitochondrial translation
0.33	GO:0023052	signaling

0.70	GO:0003746	translation elongation factor activity
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0005515	protein binding
0.32	GO:0008270	zinc ion binding

0.54	GO:0042645	mitochondrial nucleoid
0.54	GO:0043209	myelin sheath
0.45	GO:0031966	mitochondrial membrane
0.45	GO:0019866	organelle inner membrane
0.37	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

sp|P49449|CENPA_BOVIN
Histone H3-like centromeric protein A
Search

CENPA

0.74	Centromere protein A

0.56	GO:0061641	CENP-A containing chromatin organization
0.51	GO:0051382	kinetochore assembly
0.51	GO:0000132	establishment of mitotic spindle orientation
0.51	GO:0071459	protein localization to chromosome, centromeric region
0.49	GO:0000281	mitotic cytokinesis
0.46	GO:0006334	nucleosome assembly
0.37	GO:0000819	sister chromatid segregation
0.36	GO:0140014	mitotic nuclear division
0.35	GO:0031055	chromatin remodeling at centromere
0.35	GO:0034724	DNA replication-independent nucleosome organization

0.74	GO:0046982	protein heterodimerization activity
0.55	GO:0003677	DNA binding
0.47	GO:0031491	nucleosome binding

0.75	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.59	GO:0000779	condensed chromosome, centromeric region
0.56	GO:0061638	CENP-A containing chromatin
0.51	GO:0031974	membrane-enclosed lumen
0.50	GO:0005721	pericentric heterochromatin
0.49	GO:0000776	kinetochore
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|P49872|F261_BOVIN
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1
Search

PFKFB1

0.89	6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 1 splice variant 2

0.83	GO:0006003	fructose 2,6-bisphosphate metabolic process
0.83	GO:0006000	fructose metabolic process
0.74	GO:0046835	carbohydrate phosphorylation
0.47	GO:0016311	dephosphorylation
0.40	GO:0033133	positive regulation of glucokinase activity
0.40	GO:0033762	response to glucagon
0.40	GO:0031100	animal organ regeneration
0.39	GO:0051591	response to cAMP
0.39	GO:0051384	response to glucocorticoid
0.39	GO:0032868	response to insulin

0.84	GO:0003873	6-phosphofructo-2-kinase activity
0.56	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0042802	identical protein binding
0.41	GO:0070095	fructose-6-phosphate binding
0.38	GO:0019900	kinase binding
0.35	GO:0003968	RNA-directed 5'-3' RNA polymerase activity

0.56	GO:0043540	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex
0.30	GO:0016021	integral component of membrane

0.84	EC:2.7.1.105	GO:0003873
0.84	KEGG:R02732	GO:0003873

sp|P49875|IL3_BOVIN
Interleukin-3
Search

IL3

0.81	Interleukin-3

0.76	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.59	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
0.58	GO:0001660	fever generation
0.57	GO:0008284	positive regulation of cell proliferation
0.53	GO:0019221	cytokine-mediated signaling pathway

0.88	GO:0005135	interleukin-3 receptor binding
0.78	GO:0008083	growth factor activity
0.74	GO:0005125	cytokine activity
0.57	GO:0005149	interleukin-1 receptor binding

0.68

GO:0005615

extracellular space

sp|P49876|IFNAF_BOVIN
Interferon alpha-F
Search

0.88	Interferon alpha-F

0.78	GO:0051607	defense response to virus
0.76	GO:0010469	regulation of receptor activity
0.59	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein
0.59	GO:0002323	natural killer cell activation involved in immune response
0.58	GO:0042100	B cell proliferation
0.57	GO:0002286	T cell activation involved in immune response
0.57	GO:0043330	response to exogenous dsRNA
0.56	GO:0030183	B cell differentiation
0.55	GO:0002250	adaptive immune response
0.55	GO:0006959	humoral immune response

0.81	GO:0005125	cytokine activity
0.79	GO:0005126	cytokine receptor binding
0.52	GO:0032403	protein complex binding

0.73	GO:0005615	extracellular space
0.31	GO:0005622	intracellular

sp|P49877|IFNAG_BOVIN
Interferon alpha-G
Search

0.88	Interferon alpha-G

0.78	GO:0051607	defense response to virus
0.76	GO:0010469	regulation of receptor activity
0.60	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein
0.60	GO:0002323	natural killer cell activation involved in immune response
0.59	GO:0042100	B cell proliferation
0.59	GO:0002286	T cell activation involved in immune response
0.58	GO:0043330	response to exogenous dsRNA
0.58	GO:0030183	B cell differentiation
0.56	GO:0002250	adaptive immune response
0.56	GO:0006959	humoral immune response

0.81	GO:0005125	cytokine activity
0.79	GO:0005126	cytokine receptor binding
0.53	GO:0032403	protein complex binding

0.73	GO:0005615	extracellular space
0.31	GO:0005622	intracellular

sp|P49878|IFNAH_BOVIN
Interferon alpha-H
Search

0.88	Interferon alpha-H

0.78	GO:0051607	defense response to virus
0.76	GO:0010469	regulation of receptor activity
0.58	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein
0.58	GO:0002323	natural killer cell activation involved in immune response
0.57	GO:0042100	B cell proliferation
0.57	GO:0002286	T cell activation involved in immune response
0.56	GO:0043330	response to exogenous dsRNA
0.56	GO:0030183	B cell differentiation
0.55	GO:0002250	adaptive immune response
0.54	GO:0006959	humoral immune response

0.81	GO:0005125	cytokine activity
0.79	GO:0005126	cytokine receptor binding
0.51	GO:0032403	protein complex binding

0.73	GO:0005615	extracellular space
0.31	GO:0005622	intracellular

sp|P49884|ESR1_BOVIN
Estrogen receptor
Search

ESR1

0.93	Estrogen receptor

0.78	GO:0043401	steroid hormone mediated signaling pathway
0.60	GO:0060523	prostate epithelial cord elongation
0.60	GO:0071392	cellular response to estradiol stimulus
0.59	GO:0001547	antral ovarian follicle growth
0.59	GO:0060526	prostate glandular acinus morphogenesis
0.59	GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA
0.59	GO:0060687	regulation of branching involved in prostate gland morphogenesis
0.59	GO:0060068	vagina development
0.58	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling
0.58	GO:0006351	transcription, DNA-templated

0.85	GO:0030284	estrogen receptor activity
0.82	GO:0005496	steroid binding
0.64	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.60	GO:0001093	TFIIB-class transcription factor binding
0.59	GO:0001223	transcription coactivator binding
0.58	GO:0030331	estrogen receptor binding
0.57	GO:0051117	ATPase binding
0.55	GO:0008013	beta-catenin binding

0.61	GO:0005634	nucleus
0.58	GO:0097550	transcriptional preinitiation complex
0.56	GO:0035327	transcriptionally active chromatin
0.48	GO:0070013	intracellular organelle lumen
0.44	GO:0043234	protein complex
0.43	GO:0005886	plasma membrane
0.40	GO:0005737	cytoplasm
0.39	GO:0012505	endomembrane system
0.35	GO:0043204	perikaryon
0.35	GO:0043195	terminal bouton

0.35	EC:2.7.1.153	GO:0046934
0.35	KEGG:R04545	GO:0046934

sp|P49907|SEPP1_BOVIN
Selenoprotein P
Search

0.83	Selenoprotein Pa

0.45	GO:0001887	selenium compound metabolic process
0.45	GO:0007626	locomotory behavior
0.44	GO:0007420	brain development
0.44	GO:0009791	post-embryonic development
0.44	GO:0040007	growth
0.43	GO:0019953	sexual reproduction
0.40	GO:0002576	platelet degranulation
0.37	GO:0010269	response to selenium ion
0.37	GO:0006979	response to oxidative stress

0.85	GO:0008430	selenium binding
0.36	GO:0005515	protein binding

0.45	GO:0005576	extracellular region
0.41	GO:0031089	platelet dense granule lumen
0.30	GO:0016020	membrane

sp|P49951|CLH1_BOVIN
Clathrin heavy chain 1
Search

CLTC

0.65	Clathrin heavy chain

0.82	GO:0048268	clathrin coat assembly
0.69	GO:0006886	intracellular protein transport
0.68	GO:0016192	vesicle-mediated transport
0.40	GO:1900126	negative regulation of hyaluronan biosynthetic process
0.38	GO:0033572	transferrin transport
0.38	GO:1903077	negative regulation of protein localization to plasma membrane
0.37	GO:0060236	regulation of mitotic spindle organization
0.37	GO:0006914	autophagy
0.37	GO:0043112	receptor metabolic process
0.37	GO:0016482	cytosolic transport

0.85	GO:0032051	clathrin light chain binding
0.61	GO:0005198	structural molecule activity
0.46	GO:0019901	protein kinase binding
0.40	GO:0097718	disordered domain specific binding
0.38	GO:1990381	ubiquitin-specific protease binding
0.38	GO:0050750	low-density lipoprotein particle receptor binding
0.36	GO:0003725	double-stranded RNA binding
0.35	GO:0004386	helicase activity
0.35	GO:1990763	arrestin family protein binding
0.35	GO:0030506	ankyrin binding

0.84	GO:0071439	clathrin complex
0.82	GO:0030130	clathrin coat of trans-Golgi network vesicle
0.81	GO:0030132	clathrin coat of coated pit
0.47	GO:0043209	myelin sheath
0.47	GO:0072686	mitotic spindle
0.46	GO:0005764	lysosome
0.45	GO:0005768	endosome
0.40	GO:0005739	mitochondrion
0.38	GO:0042470	melanosome
0.37	GO:0005876	spindle microtubule

sp|P50154|GBGT2_BOVIN
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
Search

GNGT2

0.71	Guanine nucleotide-binding protein subunit gamma

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.47	GO:0042462	eye photoreceptor cell development
0.45	GO:0007602	phototransduction
0.41	GO:0008104	protein localization
0.38	GO:0010659	cardiac muscle cell apoptotic process
0.37	GO:0071456	cellular response to hypoxia
0.34	GO:0071377	cellular response to glucagon stimulus
0.34	GO:0022400	regulation of rhodopsin mediated signaling pathway
0.34	GO:0071482	cellular response to light stimulus
0.34	GO:0009584	detection of visible light

0.64	GO:0004871	signal transducer activity
0.45	GO:0003924	GTPase activity
0.33	GO:0005515	protein binding
0.33	GO:0003995	acyl-CoA dehydrogenase activity
0.33	GO:0050660	flavin adenine dinucleotide binding

0.81	GO:1905360	GTPase complex
0.80	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.66	GO:0098797	plasma membrane protein complex
0.37	GO:0001750	photoreceptor outer segment
0.37	GO:0001917	photoreceptor inner segment
0.36	GO:0060170	ciliary membrane

0.33

EC:1.3.99.3

GO:0003995

sp|P50227|ST1A1_BOVIN
Sulfotransferase 1A1
Search

0.57	Sulfotransferase

0.51	GO:0051923	sulfation
0.48	GO:0018958	phenol-containing compound metabolic process
0.47	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process
0.47	GO:0006068	ethanol catabolic process
0.46	GO:0006805	xenobiotic metabolic process
0.45	GO:0042445	hormone metabolic process
0.43	GO:0009812	flavonoid metabolic process
0.43	GO:0008202	steroid metabolic process
0.41	GO:0006575	cellular modified amino acid metabolic process
0.39	GO:0000103	sulfate assimilation

0.77	GO:0008146	sulfotransferase activity
0.36	GO:0005515	protein binding
0.35	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding
0.35	GO:0043199	sulfate binding
0.34	GO:0005496	steroid binding

0.38	GO:0005829	cytosol
0.35	GO:0031965	nuclear membrane

0.77

EC:2.8.2

GO:0008146

sp|P50243|DCAM_BOVIN
S-adenosylmethionine decarboxylase proenzyme
Search

AMD1

0.55	S-adenosylmethionine decarboxylase proenzyme

0.83	GO:0006597	spermine biosynthetic process
0.76	GO:0008295	spermidine biosynthetic process
0.68	GO:0006557	S-adenosylmethioninamine biosynthetic process
0.37	GO:0001701	in utero embryonic development
0.34	GO:0046500	S-adenosylmethionine metabolic process

0.80	GO:0004014	adenosylmethionine decarboxylase activity
0.49	GO:0019810	putrescine binding
0.33	GO:0005515	protein binding

0.43

GO:0005829

cytosol

0.80	EC:4.1.1.50	GO:0004014
0.80	KEGG:R00178	GO:0004014

sp|P50291|FST_BOVIN
Follistatin
Search

FST

0.97	Follistatin

0.85	GO:0032926	negative regulation of activin receptor signaling pathway
0.84	GO:0051798	positive regulation of hair follicle development
0.80	GO:0002244	hematopoietic progenitor cell differentiation
0.73	GO:0000122	negative regulation of transcription by RNA polymerase II
0.44	GO:0043616	keratinocyte proliferation
0.43	GO:0045596	negative regulation of cell differentiation
0.43	GO:0031069	hair follicle morphogenesis
0.43	GO:0001501	skeletal system development
0.43	GO:0007389	pattern specification process
0.43	GO:0007276	gamete generation

0.85	GO:0048185	activin binding
0.48	GO:0043395	heparan sulfate proteoglycan binding
0.36	GO:0016651	oxidoreductase activity, acting on NAD(P)H
0.36	GO:0004871	signal transducer activity

0.49	GO:0005576	extracellular region
0.37	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm

0.36

GO:0016651

sp|P50397|GDIB_BOVIN
Rab GDP dissociation inhibitor beta
Search

GDI2

0.68	Rab GDP dissociation inhibitor beta

0.76	GO:0007264	small GTPase mediated signal transduction
0.75	GO:0043547	positive regulation of GTPase activity
0.65	GO:0015031	protein transport
0.48	GO:0090315	negative regulation of protein targeting to membrane
0.40	GO:0050771	negative regulation of axonogenesis
0.36	GO:0045773	positive regulation of axon extension
0.36	GO:0016192	vesicle-mediated transport
0.36	GO:0051592	response to calcium ion
0.35	GO:0002283	neutrophil activation involved in immune response
0.35	GO:0002446	neutrophil mediated immunity

0.85	GO:0005093	Rab GDP-dissociation inhibitor activity
0.75	GO:0005096	GTPase activator activity
0.39	GO:0031267	small GTPase binding
0.33	GO:0003723	RNA binding
0.33	GO:0003735	structural constituent of ribosome

0.51	GO:0043209	myelin sheath
0.48	GO:0005737	cytoplasm
0.44	GO:0012505	endomembrane system
0.43	GO:0030496	midbody
0.39	GO:0043231	intracellular membrane-bounded organelle
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.36	GO:0043025	neuronal cell body
0.36	GO:0030424	axon
0.35	GO:0031983	vesicle lumen

sp|P50448|F12AI_BOVIN
Factor XIIa inhibitor
Search

SERPING1

0.94	Serpin peptidase inhibitor, clade G (C1 inhibitor), member 1

0.86	GO:0045916	negative regulation of complement activation
0.84	GO:0030193	regulation of blood coagulation
0.77	GO:0001868	regulation of complement activation, lectin pathway
0.76	GO:0010951	negative regulation of endopeptidase activity
0.61	GO:0045824	negative regulation of innate immune response

0.79

GO:0004867

serine-type endopeptidase inhibitor activity

0.73

GO:0005615

extracellular space

sp|P50595|LEP_BOVIN
Leptin
Search

LEP

0.97

Leptin

0.74	GO:0010469	regulation of receptor activity
0.62	GO:1990051	activation of protein kinase C activity
0.62	GO:0032615	interleukin-12 production
0.62	GO:0072604	interleukin-6 secretion
0.61	GO:0032868	response to insulin
0.61	GO:0032310	prostaglandin secretion
0.61	GO:0072606	interleukin-8 secretion
0.61	GO:0032817	regulation of natural killer cell proliferation
0.60	GO:0090335	regulation of brown fat cell differentiation
0.60	GO:0032099	negative regulation of appetite

0.78	GO:0005179	hormone activity
0.48	GO:0051428	peptide hormone receptor binding
0.34	GO:0005125	cytokine activity

0.65	GO:0005576	extracellular region
0.38	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P51122|AN32A_BOVIN
Acidic leucine-rich nuclear phosphoprotein 32 family member A
Search

ANP32A

0.91	Acidic leucine-rich nuclear phosphoprotein 32 family member A

0.71	GO:0006913	nucleocytoplasmic transport
0.68	GO:0043486	histone exchange
0.64	GO:0006334	nucleosome assembly
0.61	GO:0042981	regulation of apoptotic process
0.45	GO:0006351	transcription, DNA-templated
0.45	GO:2001141	regulation of RNA biosynthetic process
0.45	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.44	GO:0010468	regulation of gene expression
0.44	GO:0035067	negative regulation of histone acetylation
0.43	GO:0010977	negative regulation of neuron projection development

0.65	GO:0042393	histone binding
0.43	GO:0005178	integrin binding
0.43	GO:0008022	protein C-terminus binding
0.40	GO:0003723	RNA binding

0.76	GO:0048471	perinuclear region of cytoplasm
0.67	GO:0005783	endoplasmic reticulum
0.61	GO:0005634	nucleus
0.50	GO:0031974	membrane-enclosed lumen
0.45	GO:0044446	intracellular organelle part
0.39	GO:0005829	cytosol

sp|P51143|SC6A2_BOVIN
Sodium-dependent noradrenaline transporter
Search

SLC6A2

0.75	Sodium-dependent noradrenaline transporter

0.76	GO:0006836	neurotransmitter transport
0.55	GO:0055085	transmembrane transport
0.51	GO:0015874	norepinephrine transport
0.50	GO:0090494	dopamine uptake
0.49	GO:0001963	synaptic transmission, dopaminergic
0.47	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.45	GO:0048265	response to pain
0.44	GO:0001505	regulation of neurotransmitter levels
0.43	GO:0098657	import into cell
0.42	GO:0051649	establishment of localization in cell

0.79	GO:0005328	neurotransmitter:sodium symporter activity
0.51	GO:0005333	norepinephrine transmembrane transporter activity
0.50	GO:0005329	dopamine transmembrane transporter activity
0.45	GO:0043014	alpha-tubulin binding
0.44	GO:0048487	beta-tubulin binding
0.38	GO:0046872	metal ion binding

0.62	GO:0005887	integral component of plasma membrane
0.45	GO:0043005	neuron projection
0.43	GO:0045121	membrane raft
0.42	GO:0009986	cell surface

sp|P51176|TGM2_BOVIN
Protein-glutamine gamma-glutamyltransferase 2
Search

TGM2

0.50	Tissue-type transglutaminase

0.84	GO:0018149	peptide cross-linking
0.62	GO:0060662	salivary gland cavitation
0.62	GO:0032471	negative regulation of endoplasmic reticulum calcium ion concentration
0.62	GO:0051561	positive regulation of mitochondrial calcium ion concentration
0.61	GO:0060445	branching involved in salivary gland morphogenesis
0.59	GO:0043277	apoptotic cell clearance
0.55	GO:0043065	positive regulation of apoptotic process
0.54	GO:0045785	positive regulation of cell adhesion
0.42	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
0.42	GO:0001974	blood vessel remodeling

0.84	GO:0003810	protein-glutamine gamma-glutamyltransferase activity
0.39	GO:0019904	protein domain specific binding
0.37	GO:0032550	purine ribonucleoside binding
0.37	GO:0019001	guanyl nucleotide binding
0.36	GO:0019899	enzyme binding
0.35	GO:0046872	metal ion binding
0.35	GO:0008483	transaminase activity
0.35	GO:0032555	purine ribonucleotide binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0098772	molecular function regulator

0.51	GO:0005783	endoplasmic reticulum
0.50	GO:0005829	cytosol
0.49	GO:0031226	intrinsic component of plasma membrane
0.46	GO:0005739	mitochondrion
0.38	GO:0005925	focal adhesion
0.38	GO:0070062	extracellular exosome
0.38	GO:0031012	extracellular matrix
0.30	GO:0016021	integral component of membrane

0.84

EC:2.3.2.13

GO:0003810

sp|P51177|GUC1B_BOVIN
Guanylyl cyclase-activating protein 2
Search

GUCA1B

0.97	Guanylate cyclase activating protein 2

0.63	GO:0031284	positive regulation of guanylate cyclase activity
0.53	GO:0007601	visual perception
0.53	GO:0007602	phototransduction
0.36	GO:0022400	regulation of rhodopsin mediated signaling pathway
0.35	GO:0007168	receptor guanylyl cyclase signaling pathway
0.35	GO:0007589	body fluid secretion
0.34	GO:0007267	cell-cell signaling

0.70	GO:0005509	calcium ion binding
0.65	GO:0008048	calcium sensitive guanylate cyclase activator activity

0.40	GO:0001917	photoreceptor inner segment
0.39	GO:0001750	photoreceptor outer segment
0.35	GO:0060170	ciliary membrane

sp|P51186|CAN3_BOVIN
Calpain-3
Search

CAPN3

0.94	Calpain 3 transcription variant 10

0.85	GO:0045214	sarcomere organization
0.65	GO:0014718	positive regulation of satellite cell activation involved in skeletal muscle regeneration
0.63	GO:0033234	negative regulation of protein sumoylation
0.61	GO:0070315	G1 to G0 transition involved in cell differentiation
0.61	GO:0006508	proteolysis
0.60	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol
0.60	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.59	GO:0071472	cellular response to salt stress
0.59	GO:0071277	cellular response to calcium ion
0.59	GO:2001015	negative regulation of skeletal muscle cell differentiation

0.82	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.69	GO:0005509	calcium ion binding
0.66	GO:0055103	ligase regulator activity
0.63	GO:0031432	titin binding
0.62	GO:0008307	structural constituent of muscle
0.58	GO:0032947	protein complex scaffold activity
0.58	GO:0031402	sodium ion binding
0.34	GO:0005102	receptor binding
0.34	GO:0019899	enzyme binding
0.34	GO:0004871	signal transducer activity

0.54	GO:0030315	T-tubule
0.53	GO:0030018	Z disc
0.51	GO:0005829	cytosol
0.47	GO:0005634	nucleus
0.46	GO:0043234	protein complex

sp|P51490|OPSB_BOVIN
Short-wave-sensitive opsin 1
Search

SWS1

0.93	Blue-sensitive visual pigment opsin

0.79	GO:0007602	phototransduction
0.78	GO:0007601	visual perception
0.74	GO:0018298	protein-chromophore linkage
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.44	GO:0009584	detection of visible light
0.43	GO:0016038	absorption of visible light
0.34	GO:0001523	retinoid metabolic process

0.79	GO:0009881	photoreceptor activity
0.72	GO:0004930	G-protein coupled receptor activity

0.54	GO:0001750	photoreceptor outer segment
0.35	GO:0043195	terminal bouton
0.35	GO:0060170	ciliary membrane
0.34	GO:0044297	cell body
0.33	GO:0005887	integral component of plasma membrane

sp|P51694|PYY_BOVIN
Peptide YY
Search

PYY

0.97	Peptide YY

0.76	GO:0010469	regulation of receptor activity
0.60	GO:0032098	regulation of appetite
0.59	GO:0007631	feeding behavior
0.58	GO:0007586	digestion
0.56	GO:0007218	neuropeptide signaling pathway
0.53	GO:0007267	cell-cell signaling
0.40	GO:0032096	negative regulation of response to food
0.39	GO:0008283	cell proliferation
0.37	GO:0007010	cytoskeleton organization

0.79	GO:0005179	hormone activity
0.56	GO:0001664	G-protein coupled receptor binding

0.66

GO:0005576

extracellular region

sp|P51749|CD40L_BOVIN
CD40 ligand
Search

sp|P51866|PECA1_BOVIN
Platelet endothelial cell adhesion molecule
Search

PECAM1

0.95	Platelet endothelial cell adhesion molecule

0.68	GO:0090673	endothelial cell-matrix adhesion
0.66	GO:0001886	endothelial cell morphogenesis
0.64	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein
0.63	GO:0043542	endothelial cell migration
0.62	GO:0007266	Rho protein signal transduction
0.60	GO:0001525	angiogenesis
0.59	GO:0042060	wound healing
0.59	GO:0030334	regulation of cell migration
0.43	GO:0050904	diapedesis
0.43	GO:0072672	neutrophil extravasation

0.39	GO:0042803	protein homodimerization activity
0.36	GO:0019903	protein phosphatase binding

0.66	GO:0030485	smooth muscle contractile fiber
0.62	GO:0045121	membrane raft
0.60	GO:0009897	external side of plasma membrane
0.43	GO:0030054	cell junction
0.39	GO:0005615	extracellular space
0.39	GO:1903561	extracellular vesicle
0.38	GO:0031092	platelet alpha granule membrane
0.36	GO:0001726	ruffle
0.30	GO:0031224	intrinsic component of membrane

sp|P51867|TNR6_BOVIN
Tumor necrosis factor receptor superfamily member 6
Search

FAS

0.95	Fas cell surface death receptor

0.78	GO:0006915	apoptotic process
0.74	GO:0006955	immune response
0.61	GO:0007165	signal transduction
0.56	GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
0.55	GO:0071455	cellular response to hyperoxia
0.55	GO:0070266	necroptotic process
0.54	GO:0071260	cellular response to mechanical stimulus
0.53	GO:0034198	cellular response to amino acid starvation
0.52	GO:0032872	regulation of stress-activated MAPK cascade
0.50	GO:0001934	positive regulation of protein phosphorylation

0.70	GO:0004888	transmembrane signaling receptor activity
0.51	GO:0005516	calmodulin binding
0.50	GO:0019900	kinase binding
0.48	GO:0042802	identical protein binding
0.48	GO:0043120	tumor necrosis factor binding

0.56	GO:0031265	CD95 death-inducing signaling complex
0.51	GO:0045121	membrane raft
0.50	GO:0016604	nuclear body
0.49	GO:0009986	cell surface
0.46	GO:0005829	cytosol
0.40	GO:0005887	integral component of plasma membrane
0.39	GO:0005739	mitochondrion
0.35	GO:0098552	side of membrane
0.34	GO:0005576	extracellular region

sp|P52173|IL5_BOVIN
Interleukin-5
Search

IL5

0.96	Interleukin-5

0.76	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.68	GO:0051024	positive regulation of immunoglobulin secretion
0.67	GO:0071803	positive regulation of podosome assembly
0.63	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
0.62	GO:0051091	positive regulation of DNA binding transcription factor activity
0.57	GO:0045893	positive regulation of transcription, DNA-templated
0.44	GO:0045645	positive regulation of eosinophil differentiation
0.42	GO:0030890	positive regulation of B cell proliferation
0.42	GO:0046427	positive regulation of JAK-STAT cascade

0.87	GO:0005137	interleukin-5 receptor binding
0.80	GO:0005125	cytokine activity
0.78	GO:0008083	growth factor activity

0.73

GO:0005615

extracellular space

sp|P52174|NDKA1_BOVIN
Nucleoside diphosphate kinase A 1
Search

0.46	Nucleoside diphosphate kinase A

0.79	GO:0006228	UTP biosynthetic process
0.79	GO:0006183	GTP biosynthetic process
0.75	GO:0046036	CTP metabolic process
0.70	GO:0006165	nucleoside diphosphate phosphorylation
0.48	GO:0042981	regulation of apoptotic process
0.48	GO:0050679	positive regulation of epithelial cell proliferation
0.47	GO:0007595	lactation
0.46	GO:0043388	positive regulation of DNA binding
0.44	GO:2000026	regulation of multicellular organismal development
0.42	GO:0045597	positive regulation of cell differentiation

0.79	GO:0004550	nucleoside diphosphate kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0043024	ribosomal small subunit binding
0.42	GO:0042802	identical protein binding
0.42	GO:0004536	deoxyribonuclease activity
0.41	GO:0019215	intermediate filament binding
0.40	GO:0019001	guanyl nucleotide binding

0.50	GO:0001726	ruffle
0.46	GO:0043209	myelin sheath
0.45	GO:0031256	leading edge membrane
0.45	GO:0031253	cell projection membrane
0.43	GO:0030027	lamellipodium
0.42	GO:0005829	cytosol
0.42	GO:0005634	nucleus
0.41	GO:0005925	focal adhesion
0.40	GO:0005739	mitochondrion
0.39	GO:0070062	extracellular exosome

0.79

EC:2.7.4.6

GO:0004550

sp|P52175|NDKA2_BOVIN
Nucleoside diphosphate kinase A 2
Search

0.46	Nucleoside diphosphate kinase A

0.78	GO:0006228	UTP biosynthetic process
0.78	GO:0006183	GTP biosynthetic process
0.75	GO:0046036	CTP metabolic process
0.70	GO:0006165	nucleoside diphosphate phosphorylation
0.49	GO:0042981	regulation of apoptotic process
0.48	GO:0050679	positive regulation of epithelial cell proliferation
0.46	GO:0007595	lactation
0.46	GO:0043388	positive regulation of DNA binding
0.44	GO:2000026	regulation of multicellular organismal development
0.42	GO:0045597	positive regulation of cell differentiation

0.79	GO:0004550	nucleoside diphosphate kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0043024	ribosomal small subunit binding
0.42	GO:0042802	identical protein binding
0.41	GO:0004536	deoxyribonuclease activity
0.41	GO:0019215	intermediate filament binding
0.40	GO:0046872	metal ion binding

0.50	GO:0001726	ruffle
0.46	GO:0043209	myelin sheath
0.45	GO:0031256	leading edge membrane
0.45	GO:0031253	cell projection membrane
0.43	GO:0030027	lamellipodium
0.42	GO:0005829	cytosol
0.42	GO:0005634	nucleus
0.41	GO:0005925	focal adhesion
0.40	GO:0005739	mitochondrion
0.39	GO:0070062	extracellular exosome

0.79

EC:2.7.4.6

GO:0004550

sp|P52176|MMP9_BOVIN
Matrix metalloproteinase-9
Search

MMP9

0.66	Matrix metalloproteinase

0.78	GO:0030574	collagen catabolic process
0.74	GO:0050900	leukocyte migration
0.73	GO:0001503	ossification
0.61	GO:0006508	proteolysis
0.58	GO:2001268	negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
0.58	GO:1900122	positive regulation of receptor binding
0.58	GO:0051549	positive regulation of keratinocyte migration
0.57	GO:1904707	positive regulation of vascular smooth muscle cell proliferation
0.56	GO:0090200	positive regulation of release of cytochrome c from mitochondria
0.56	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway

0.70	GO:0004222	metalloendopeptidase activity
0.63	GO:0008270	zinc ion binding
0.50	GO:0042802	identical protein binding
0.38	GO:0001968	fibronectin binding
0.38	GO:0004252	serine-type endopeptidase activity
0.37	GO:0032403	protein complex binding

0.74	GO:0031012	extracellular matrix
0.50	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.34	GO:0043234	protein complex
0.32	GO:1904724	tertiary granule lumen
0.32	GO:1904813	ficolin-1-rich granule lumen
0.30	GO:0016020	membrane

0.70

GO:0004222

sp|P52193|CALR_BOVIN
Calreticulin
Search

0.77	Calreticulin like

0.69	GO:0006457	protein folding
0.50	GO:1901164	negative regulation of trophoblast cell migration
0.50	GO:0002502	peptide antigen assembly with MHC class I protein complex
0.50	GO:2000510	positive regulation of dendritic cell chemotaxis
0.50	GO:0048387	negative regulation of retinoic acid receptor signaling pathway
0.49	GO:0090398	cellular senescence
0.49	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading
0.49	GO:0033144	negative regulation of intracellular steroid hormone receptor signaling pathway
0.49	GO:0071157	negative regulation of cell cycle arrest
0.48	GO:0006611	protein export from nucleus

0.71	GO:0051082	unfolded protein binding
0.70	GO:0005509	calcium ion binding
0.49	GO:0050681	androgen receptor binding
0.48	GO:0005178	integrin binding
0.46	GO:0031625	ubiquitin protein ligase binding
0.45	GO:0003729	mRNA binding
0.43	GO:0030246	carbohydrate binding
0.35	GO:0008009	chemokine activity
0.35	GO:0042562	hormone binding
0.34	GO:0042277	peptide binding

0.70	GO:0005783	endoplasmic reticulum
0.47	GO:0005844	polysome
0.46	GO:0048471	perinuclear region of cytoplasm
0.46	GO:0009897	external side of plasma membrane
0.45	GO:0005635	nuclear envelope
0.44	GO:0005615	extracellular space
0.43	GO:0070013	intracellular organelle lumen
0.43	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.43	GO:0005829	cytosol
0.42	GO:0031984	organelle subcompartment

sp|P52205|ROM1_BOVIN
Rod outer segment membrane protein 1
Search

ROM1

0.92	Retinal outer segment membrane protein 1

0.78	GO:0007601	visual perception
0.60	GO:0060041	retina development in camera-type eye
0.55	GO:0001754	eye photoreceptor cell differentiation
0.55	GO:0048593	camera-type eye morphogenesis
0.53	GO:0001944	vasculature development
0.46	GO:0007166	cell surface receptor signaling pathway
0.42	GO:0060255	regulation of macromolecule metabolic process
0.40	GO:0007155	cell adhesion
0.34	GO:1903525	regulation of membrane tubulation
0.34	GO:0009645	response to low light intensity stimulus

0.34	GO:0005515	protein binding
0.34	GO:0004637	phosphoribosylamine-glycine ligase activity

0.61	GO:0001750	photoreceptor outer segment
0.56	GO:0060170	ciliary membrane
0.44	GO:0005887	integral component of plasma membrane
0.33	GO:0055037	recycling endosome
0.33	GO:0005795	Golgi stack
0.33	GO:0005783	endoplasmic reticulum
0.32	GO:0043234	protein complex

0.34	EC:6.3.4.13	GO:0004637
0.34	KEGG:R04144	GO:0004637

sp|P52476|AL1B1_BOVIN
Aldehyde dehydrogenase X, mitochondrial (Fragment)
Search

0.62	Aldehyde dehydrogenase X, mitochondrial

0.53	GO:0055114	oxidation-reduction process
0.45	GO:0006068	ethanol catabolic process
0.44	GO:0006117	acetaldehyde metabolic process
0.42	GO:0045471	response to ethanol
0.42	GO:0010941	regulation of cell death
0.39	GO:2001038	regulation of cellular response to drug
0.39	GO:0021768	nucleus accumbens development
0.39	GO:0060166	olfactory pit development
0.39	GO:0060324	face development
0.39	GO:0070384	Harderian gland development

0.69	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.39	GO:0070324	thyroid hormone binding
0.39	GO:0051287	NAD binding
0.37	GO:0042802	identical protein binding
0.36	GO:0046983	protein dimerization activity
0.34	GO:0043168	anion binding

0.47	GO:0070013	intracellular organelle lumen
0.47	GO:0005739	mitochondrion
0.45	GO:0044428	nuclear part
0.36	GO:0005829	cytosol
0.34	GO:0070062	extracellular exosome
0.34	GO:0005886	plasma membrane

0.69

GO:0016620

sp|P52505|ACPM_BOVIN
Acyl carrier protein, mitochondrial
Search

NDUFAB1

0.44	Acyl carrier protein, mitochondrial

0.70	GO:0006633	fatty acid biosynthetic process
0.55	GO:0032981	mitochondrial respiratory chain complex I assembly
0.50	GO:0009249	protein lipoylation
0.46	GO:0009245	lipid A biosynthetic process
0.37	GO:0006120	mitochondrial electron transport, NADH to ubiquinone
0.34	GO:0006635	fatty acid beta-oxidation

0.52	GO:0000035	acyl binding
0.48	GO:0044620	ACP phosphopantetheine attachment site binding
0.47	GO:0140104	molecular carrier activity
0.46	GO:0031177	phosphopantetheine binding
0.37	GO:0005504	fatty acid binding
0.35	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.34	GO:0005509	calcium ion binding
0.33	GO:0005515	protein binding
0.32	GO:0003676	nucleic acid binding

0.53	GO:0005747	mitochondrial respiratory chain complex I
0.47	GO:0005654	nucleoplasm
0.44	GO:0005829	cytosol
0.36	GO:0005759	mitochondrial matrix
0.30	GO:0016021	integral component of membrane

0.35

GO:0008137

sp|P52556|BLVRB_BOVIN
Flavin reductase (NADPH)
Search

BLVRB

0.47	Biliverdin reductase B

0.84	GO:0042167	heme catabolic process
0.51	GO:0055114	oxidation-reduction process
0.38	GO:0000183	chromatin silencing at rDNA

0.85	GO:0004074	biliverdin reductase activity
0.84	GO:0042602	riboflavin reductase (NADPH) activity
0.34	GO:0003677	DNA binding

0.68	GO:0005654	nucleoplasm
0.66	GO:0005829	cytosol
0.54	GO:0005886	plasma membrane
0.53	GO:0043195	terminal bouton
0.43	GO:0070062	extracellular exosome
0.38	GO:0005720	nuclear heterochromatin

0.85	EC:1.3.1.24	GO:0004074
0.84	KEGG:R05707	GO:0042602

sp|P52897|PGFS2_BOVIN
Prostaglandin F synthase 2
Search

0.93	Dihydrodiol dehydrogenase 3

0.53	GO:0055114	oxidation-reduction process
0.46	GO:0044597	daunorubicin metabolic process
0.45	GO:0071395	cellular response to jasmonic acid stimulus
0.44	GO:0044598	doxorubicin metabolic process
0.43	GO:0008202	steroid metabolic process
0.42	GO:0071799	cellular response to prostaglandin D stimulus
0.41	GO:0006692	prostanoid metabolic process
0.41	GO:1900053	negative regulation of retinoic acid biosynthetic process
0.41	GO:0016488	farnesol catabolic process
0.41	GO:0042574	retinal metabolic process

0.54	GO:0016491	oxidoreductase activity
0.40	GO:0032052	bile acid binding
0.35	GO:0015125	bile acid transmembrane transporter activity
0.34	GO:0004452	isopentenyl-diphosphate delta-isomerase activity
0.33	GO:0005515	protein binding
0.32	GO:0016787	hydrolase activity

0.38	GO:0070062	extracellular exosome
0.37	GO:0005829	cytosol
0.36	GO:0005634	nucleus

0.54	EC:1	GO:0016491
0.34	KEGG:R01123	GO:0004452

sp|P52898|DDBX_BOVIN
Dihydrodiol dehydrogenase 3
Search

0.93	Dihydrodiol dehydrogenase 3

0.53	GO:0055114	oxidation-reduction process
0.47	GO:0044597	daunorubicin metabolic process
0.46	GO:0071395	cellular response to jasmonic acid stimulus
0.44	GO:0044598	doxorubicin metabolic process
0.44	GO:0008202	steroid metabolic process
0.43	GO:0071799	cellular response to prostaglandin D stimulus
0.43	GO:1900053	negative regulation of retinoic acid biosynthetic process
0.43	GO:0016488	farnesol catabolic process
0.43	GO:2000224	regulation of testosterone biosynthetic process
0.42	GO:0042574	retinal metabolic process

0.54	GO:0016491	oxidoreductase activity
0.40	GO:0032052	bile acid binding
0.35	GO:0015125	bile acid transmembrane transporter activity
0.34	GO:0004452	isopentenyl-diphosphate delta-isomerase activity
0.33	GO:0005515	protein binding
0.32	GO:0016787	hydrolase activity

0.37	GO:0005829	cytosol
0.37	GO:0070062	extracellular exosome
0.36	GO:0005634	nucleus

0.54	EC:1	GO:0016491
0.34	KEGG:R01123	GO:0004452

sp|P53346|ONCM_BOVIN
Oncostatin-M
Search

OSM

0.97	Oncostatin-M

0.77	GO:0038165	oncostatin-M-mediated signaling pathway
0.76	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.73	GO:0046888	negative regulation of hormone secretion
0.72	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein
0.71	GO:0033138	positive regulation of peptidyl-serine phosphorylation
0.68	GO:0042127	regulation of cell proliferation
0.67	GO:0043410	positive regulation of MAPK cascade
0.64	GO:0045944	positive regulation of transcription by RNA polymerase II
0.46	GO:0040008	regulation of growth

0.81	GO:0005125	cytokine activity
0.80	GO:0005147	oncostatin-M receptor binding
0.66	GO:0008083	growth factor activity

0.66

GO:0005576

extracellular region

sp|P53348|BTG1_BOVIN
Protein BTG1
Search

BTG1

0.96	B-cell translocation protein 1, anti-proliferative

0.79	GO:0008285	negative regulation of cell proliferation
0.57	GO:2000271	positive regulation of fibroblast apoptotic process
0.57	GO:0045603	positive regulation of endothelial cell differentiation
0.55	GO:0045663	positive regulation of myoblast differentiation
0.54	GO:0045766	positive regulation of angiogenesis
0.48	GO:0021542	dentate gyrus development
0.48	GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
0.47	GO:0035914	skeletal muscle cell differentiation
0.47	GO:0008213	protein alkylation
0.47	GO:0008306	associative learning

0.48	GO:0019899	enzyme binding
0.37	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.34	GO:0003712	transcription cofactor activity

0.44	GO:0005634	nucleus
0.39	GO:0005737	cytoplasm
0.35	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

sp|P53619|COPD_BOVIN
Coatomer subunit delta
Search

ARCN1

0.68	Coatomer subunit delta

0.81	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.65	GO:0015031	protein transport
0.56	GO:0021691	cerebellar Purkinje cell layer maturation
0.52	GO:0008344	adult locomotory behavior
0.52	GO:0043473	pigmentation
0.35	GO:0006891	intra-Golgi vesicle-mediated transport
0.34	GO:0006888	ER to Golgi vesicle-mediated transport
0.33	GO:0034613	cellular protein localization

0.34	GO:0003723	RNA binding
0.33	GO:0005515	protein binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.81	GO:0030126	COPI vesicle coat
0.73	GO:0000139	Golgi membrane
0.46	GO:0005783	endoplasmic reticulum
0.34	GO:0030133	transport vesicle
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0005829	cytosol

sp|P53620|COPG1_BOVIN
Coatomer subunit gamma-1
Search

COPG1

0.70	Coatomer subunit gamma

0.69	GO:0006886	intracellular protein transport
0.69	GO:0016192	vesicle-mediated transport
0.37	GO:0051683	establishment of Golgi localization
0.36	GO:0072384	organelle transport along microtubule

0.61	GO:0005198	structural molecule activity
0.34	GO:0005515	protein binding
0.32	GO:0016757	transferase activity, transferring glycosyl groups

0.81	GO:0030126	COPI vesicle coat
0.67	GO:0000139	Golgi membrane
0.36	GO:0005829	cytosol
0.36	GO:0030133	transport vesicle
0.34	GO:0099503	secretory vesicle
0.34	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016757

sp|P53710|ITA2_BOVIN
Integrin alpha-2 (Fragment)
Search

ITGA2

0.96	Platelet membrane glycoprotein Ia

0.79	GO:0007229	integrin-mediated signaling pathway
0.71	GO:0007155	cell adhesion
0.60	GO:0006929	substrate-dependent cell migration
0.59	GO:0048333	mesodermal cell differentiation
0.59	GO:0038065	collagen-activated signaling pathway
0.47	GO:0010922	positive regulation of phosphatase activity
0.43	GO:0042127	regulation of cell proliferation
0.43	GO:0045123	cellular extravasation
0.43	GO:0033343	positive regulation of collagen binding
0.43	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway

0.65	GO:0098639	collagen binding involved in cell-matrix adhesion
0.60	GO:0038064	collagen receptor activity
0.59	GO:0001540	amyloid-beta binding
0.42	GO:0019903	protein phosphatase binding
0.41	GO:0043236	laminin binding
0.40	GO:0005178	integrin binding
0.38	GO:0046982	protein heterodimerization activity
0.37	GO:0001618	virus receptor activity
0.36	GO:0043395	heparan sulfate proteoglycan binding
0.35	GO:0046872	metal ion binding

0.80	GO:0008305	integrin complex
0.61	GO:0045178	basal part of cell
0.59	GO:0009897	external side of plasma membrane
0.59	GO:0005925	focal adhesion
0.40	GO:0043679	axon terminus
0.39	GO:0030424	axon
0.39	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0005634	nucleus
0.35	GO:0043204	perikaryon
0.35	GO:0001669	acrosomal vesicle

sp|P53712|ITB1_BOVIN
Integrin beta-1
Search

ITGB1

0.67	Integrin beta

0.82	GO:0007160	cell-matrix adhesion
0.80	GO:0007229	integrin-mediated signaling pathway
0.60	GO:0010710	regulation of collagen catabolic process
0.58	GO:0033627	cell adhesion mediated by integrin
0.57	GO:0071404	cellular response to low-density lipoprotein particle stimulus
0.57	GO:1903078	positive regulation of protein localization to plasma membrane
0.56	GO:0021943	formation of radial glial scaffolds
0.56	GO:2000811	negative regulation of anoikis
0.56	GO:0031623	receptor internalization
0.56	GO:0050901	leukocyte tethering or rolling

0.65	GO:0004872	receptor activity
0.58	GO:0001968	fibronectin binding
0.57	GO:0019960	C-X3-C chemokine binding
0.57	GO:0098639	collagen binding involved in cell-matrix adhesion
0.54	GO:0043236	laminin binding
0.54	GO:0002020	protease binding
0.53	GO:0046982	protein heterodimerization activity
0.53	GO:0005178	integrin binding
0.52	GO:0045296	cadherin binding
0.49	GO:0003779	actin binding

0.81	GO:0008305	integrin complex
0.60	GO:0071438	invadopodium membrane
0.58	GO:0032587	ruffle membrane
0.55	GO:0035748	myelin sheath abaxonal region
0.55	GO:0005925	focal adhesion
0.54	GO:0042383	sarcolemma
0.54	GO:0031594	neuromuscular junction
0.54	GO:0030175	filopodium
0.53	GO:0014704	intercalated disc
0.53	GO:0009986	cell surface

sp|P53781|TTP_BOVIN
mRNA decay activator protein ZFP36
Search

ZFP36

0.96	Tristetraproline

0.67	GO:1904246	negative regulation of polynucleotide adenylyltransferase activity
0.66	GO:0045085	negative regulation of interleukin-2 biosynthetic process
0.64	GO:0061158	3'-UTR-mediated mRNA destabilization
0.64	GO:0038066	p38MAPK cascade
0.63	GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
0.62	GO:0045600	positive regulation of fat cell differentiation
0.61	GO:0035278	miRNA mediated inhibition of translation
0.61	GO:0045638	negative regulation of myeloid cell differentiation
0.60	GO:0071356	cellular response to tumor necrosis factor
0.60	GO:0071222	cellular response to lipopolysaccharide

0.64	GO:0035925	mRNA 3'-UTR AU-rich region binding
0.63	GO:0071889	14-3-3 protein binding
0.56	GO:0070063	RNA polymerase binding
0.54	GO:0046872	metal ion binding
0.42	GO:0031072	heat shock protein binding
0.42	GO:0019957	C-C chemokine binding
0.39	GO:0019901	protein kinase binding
0.36	GO:0003677	DNA binding
0.36	GO:0003727	single-stranded RNA binding
0.33	GO:0070577	lysine-acetylated histone binding

0.59	GO:0030014	CCR4-NOT complex
0.52	GO:0005829	cytosol
0.48	GO:0005634	nucleus
0.47	GO:0030529	intracellular ribonucleoprotein complex
0.47	GO:0098745	Dcp1-Dcp2 complex
0.45	GO:0070578	RISC-loading complex
0.43	GO:0000178	exosome (RNase complex)
0.38	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

sp|P53793|SC5A3_BOVIN
Sodium/myo-inositol cotransporter
Search

SLC5A3

0.96	Sodium/myo-inositol cotransporter

0.57	GO:0015798	myo-inositol transport
0.55	GO:0055085	transmembrane transport
0.51	GO:0043576	regulation of respiratory gaseous exchange
0.50	GO:0006020	inositol metabolic process
0.50	GO:0007422	peripheral nervous system development
0.38	GO:0006814	sodium ion transport
0.33	GO:0043043	peptide biosynthetic process
0.33	GO:0044267	cellular protein metabolic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process

0.57	GO:0022857	transmembrane transporter activity
0.34	GO:0019843	rRNA binding
0.33	GO:0003735	structural constituent of ribosome

0.41	GO:0005887	integral component of plasma membrane
0.33	GO:0005840	ribosome

sp|P54131|ACHA7_BOVIN
Neuronal acetylcholine receptor subunit alpha-7
Search

CHRNA7

0.89	LOW QUALITY PROTEIN: neuronal acetylcholine receptor subunit alpha-7

0.77	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.51	GO:0035094	response to nicotine
0.49	GO:1905920	positive regulation of CoA-transferase activity
0.48	GO:0001988	positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure
0.48	GO:0050893	sensory processing
0.48	GO:0032720	negative regulation of tumor necrosis factor production
0.48	GO:0060112	generation of ovulation cycle rhythm
0.48	GO:0140059	dendrite arborization
0.47	GO:1905906	regulation of amyloid fibril formation

0.80	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0004888	transmembrane signaling receptor activity
0.42	GO:0017081	chloride channel regulator activity
0.42	GO:0042166	acetylcholine binding
0.42	GO:0001540	amyloid-beta binding
0.41	GO:0015643	toxic substance binding
0.39	GO:0042803	protein homodimerization activity
0.35	GO:0008179	adenylate cyclase binding
0.35	GO:0097110	scaffold protein binding
0.35	GO:0051117	ATPase binding

0.76	GO:0045211	postsynaptic membrane
0.72	GO:0030054	cell junction
0.54	GO:0030424	axon
0.54	GO:0043204	perikaryon
0.52	GO:0120038	plasma membrane bounded cell projection part
0.52	GO:0097447	dendritic tree
0.46	GO:0005892	acetylcholine-gated channel complex
0.44	GO:0031256	leading edge membrane
0.44	GO:0009897	external side of plasma membrane
0.44	GO:0016324	apical plasma membrane

sp|P54149|MSRA_BOVIN
Mitochondrial peptide methionine sulfoxide reductase
Search

MSRA

0.43	Mitochondrial peptide methionine sulfoxide reductase

0.53	GO:0055114	oxidation-reduction process
0.44	GO:0036211	protein modification process
0.42	GO:0044267	cellular protein metabolic process
0.35	GO:0007568	aging
0.34	GO:0006555	methionine metabolic process
0.34	GO:0006979	response to oxidative stress
0.32	GO:0006508	proteolysis

0.78	GO:0008113	peptide-methionine (S)-S-oxide reductase activity
0.33	GO:0004252	serine-type endopeptidase activity

0.47	GO:0015629	actin cytoskeleton
0.46	GO:0005654	nucleoplasm
0.45	GO:0005829	cytosol
0.42	GO:0005739	mitochondrion
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.78

EC:1.8.4 EC:1.8.4.11

GO:0008113

sp|P54228|CTHL6_BOVIN
Cathelicidin-6
Search

0.95	Preprocathelicidin antimicrobial peptide

0.72	GO:0006952	defense response
0.58	GO:0009617	response to bacterium
0.45	GO:0044140	negative regulation of growth of symbiont on or near host surface
0.44	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.44	GO:0044130	negative regulation of growth of symbiont in host
0.43	GO:0051851	modification by host of symbiont morphology or physiology
0.43	GO:0031640	killing of cells of other organism
0.42	GO:0051818	disruption of cells of other organism involved in symbiotic interaction
0.38	GO:0019835	cytolysis
0.36	GO:0009620	response to fungus

0.32	GO:0046872	metal ion binding
0.32	GO:0003676	nucleic acid binding

0.66	GO:0005576	extracellular region
0.43	GO:0042581	specific granule
0.34	GO:0042995	cell projection
0.30	GO:0016020	membrane

sp|P54229|CTHL5_BOVIN
Cathelicidin-5
Search

0.95	Preprocathelicidin antimicrobial peptide

0.72	GO:0006952	defense response
0.58	GO:0009617	response to bacterium
0.47	GO:0044140	negative regulation of growth of symbiont on or near host surface
0.45	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.44	GO:0044130	negative regulation of growth of symbiont in host
0.44	GO:0051851	modification by host of symbiont morphology or physiology
0.43	GO:0031640	killing of cells of other organism
0.43	GO:0051818	disruption of cells of other organism involved in symbiotic interaction
0.39	GO:0019835	cytolysis
0.37	GO:0009620	response to fungus

0.33	GO:0005515	protein binding
0.32	GO:0046872	metal ion binding
0.32	GO:0003676	nucleic acid binding

0.66	GO:0005576	extracellular region
0.45	GO:0042581	specific granule
0.35	GO:1904724	tertiary granule lumen
0.35	GO:0042995	cell projection
0.34	GO:0034774	secretory granule lumen
0.30	GO:0031224	intrinsic component of membrane

sp|P54281|ECLC_BOVIN
Epithelial chloride channel protein
Search

0.80	Calcium-activated chloride channel

0.76	GO:1902476	chloride transmembrane transport
0.39	GO:0043276	anoikis
0.39	GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand
0.37	GO:0006816	calcium ion transport
0.37	GO:0006508	proteolysis
0.34	GO:0071456	cellular response to hypoxia
0.33	GO:0007155	cell adhesion
0.33	GO:0034765	regulation of ion transmembrane transport
0.32	GO:0098662	inorganic cation transmembrane transport

0.85	GO:0061778	intracellular chloride channel activity
0.71	GO:0022839	ion gated channel activity
0.71	GO:0008381	mechanosensitive ion channel activity
0.42	GO:0022834	ligand-gated channel activity
0.38	GO:0008237	metallopeptidase activity
0.35	GO:0046872	metal ion binding
0.34	GO:0004175	endopeptidase activity
0.33	GO:0005262	calcium channel activity
0.33	GO:0022832	voltage-gated channel activity

0.48	GO:0005887	integral component of plasma membrane
0.43	GO:0005902	microvillus
0.43	GO:0012505	endomembrane system
0.42	GO:0099503	secretory vesicle
0.42	GO:0030054	cell junction
0.40	GO:0005829	cytosol
0.40	GO:0044428	nuclear part
0.38	GO:0031090	organelle membrane
0.38	GO:0031967	organelle envelope
0.37	GO:0016324	apical plasma membrane

sp|P54349|IL12A_BOVIN
Interleukin-12 subunit alpha
Search

IL12A

0.97	Interleukin-12 subunit alpha

0.76	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.65	GO:0051135	positive regulation of NK T cell activation
0.65	GO:0002857	positive regulation of natural killer cell mediated immune response to tumor cell
0.65	GO:0002858	regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
0.65	GO:2000510	positive regulation of dendritic cell chemotaxis
0.64	GO:0034393	positive regulation of smooth muscle cell apoptotic process
0.64	GO:0001916	positive regulation of T cell mediated cytotoxicity
0.64	GO:0032700	negative regulation of interleukin-17 production
0.64	GO:0032816	positive regulation of natural killer cell activation

0.87	GO:0005143	interleukin-12 receptor binding
0.80	GO:0005125	cytokine activity
0.78	GO:0008083	growth factor activity
0.70	GO:0042163	interleukin-12 beta subunit binding
0.68	GO:0019975	interleukin-17 binding
0.57	GO:0046982	protein heterodimerization activity

0.73	GO:0005615	extracellular space
0.48	GO:0043234	protein complex
0.40	GO:0005737	cytoplasm
0.37	GO:0097708	intracellular vesicle
0.36	GO:0012505	endomembrane system
0.36	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part
0.34	GO:0043231	intracellular membrane-bounded organelle

sp|P55052|FABP5_BOVIN
Fatty acid-binding protein, epidermal
Search

FABP5

0.93	Fatty acid-binding protein, epidermal

0.49	GO:0006656	phosphatidylcholine biosynthetic process
0.48	GO:0015758	glucose transport
0.44	GO:0006006	glucose metabolic process
0.41	GO:0050727	regulation of inflammatory response
0.38	GO:0050872	white fat cell differentiation
0.38	GO:0071285	cellular response to lithium ion
0.37	GO:0050873	brown fat cell differentiation
0.37	GO:0042632	cholesterol homeostasis
0.37	GO:0001816	cytokine production
0.37	GO:0071356	cellular response to tumor necrosis factor

0.72	GO:0008289	lipid binding
0.41	GO:0033293	monocarboxylic acid binding
0.35	GO:0015349	thyroid hormone transmembrane transporter activity
0.34	GO:0005515	protein binding

0.38	GO:0043209	myelin sheath
0.37	GO:0070062	extracellular exosome
0.36	GO:0035578	azurophil granule lumen
0.35	GO:0030667	secretory granule membrane
0.34	GO:0005654	nucleoplasm
0.34	GO:0005829	cytosol
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P55106|GDF6_BOVIN
Growth/differentiation factor 6
Search

GDF6

0.87	Growth differentiation factor 6

0.75	GO:0010469	regulation of receptor activity
0.66	GO:0090100	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
0.66	GO:0060393	regulation of pathway-restricted SMAD protein phosphorylation
0.65	GO:0060389	pathway-restricted SMAD protein phosphorylation
0.65	GO:0060395	SMAD protein signal transduction
0.65	GO:0032924	activin receptor signaling pathway
0.63	GO:0030509	BMP signaling pathway
0.62	GO:0032332	positive regulation of chondrocyte differentiation
0.60	GO:0001934	positive regulation of protein phosphorylation
0.56	GO:1900744	regulation of p38MAPK cascade

0.78	GO:0008083	growth factor activity
0.53	GO:0042803	protein homodimerization activity
0.52	GO:0005160	transforming growth factor beta receptor binding
0.50	GO:0005125	cytokine activity
0.32	GO:0003677	DNA binding

0.66	GO:0005576	extracellular region
0.34	GO:0005720	nuclear heterochromatin
0.34	GO:0005750	mitochondrial respiratory chain complex III
0.30	GO:0016021	integral component of membrane

sp|P55156|MTP_BOVIN
Microsomal triglyceride transfer protein large subunit (Fragment)
Search

MTTP

0.87	microsomal triglyceride transfer protein large subunit precursor

0.74	GO:0006869	lipid transport
0.56	GO:0042632	cholesterol homeostasis
0.54	GO:0007623	circadian rhythm
0.54	GO:0006641	triglyceride metabolic process
0.53	GO:0042158	lipoprotein biosynthetic process
0.53	GO:0042953	lipoprotein transport
0.44	GO:0036211	protein modification process
0.44	GO:0034377	plasma lipoprotein particle assembly
0.42	GO:0002040	sprouting angiogenesis
0.42	GO:0044267	cellular protein metabolic process

0.76	GO:0005319	lipid transporter activity
0.41	GO:0046982	protein heterodimerization activity
0.40	GO:0034185	apolipoprotein binding
0.39	GO:0008289	lipid binding
0.32	GO:0020037	heme binding
0.32	GO:0009055	electron transfer activity
0.32	GO:0046872	metal ion binding
0.32	GO:0016874	ligase activity

0.51	GO:0005783	endoplasmic reticulum
0.39	GO:0031528	microvillus membrane
0.39	GO:0031526	brush border membrane
0.38	GO:0016323	basolateral plasma membrane
0.38	GO:0043235	receptor complex
0.37	GO:0031982	vesicle
0.37	GO:0005794	Golgi apparatus
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016874

sp|P55203|GUC2D_BOVIN
Retinal guanylyl cyclase 1
Search

GUCY2D

0.57	Guanylate cyclase

0.82	GO:0006182	cGMP biosynthetic process
0.63	GO:0006468	protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.46	GO:0007601	visual perception
0.45	GO:0050962	detection of light stimulus involved in sensory perception
0.43	GO:0035845	photoreceptor cell outer segment organization
0.43	GO:0009584	detection of visible light

0.82	GO:0004383	guanylate cyclase activity
0.63	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0004016	adenylate cyclase activity

0.49	GO:0008074	guanylate cyclase complex, soluble
0.38	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.82

EC:4.6.1.2

GO:0004383

sp|P55206|ANFC_BOVIN
C-type natriuretic peptide
Search

NPPC

0.96	C-type natriuretic peptide

0.79	GO:0050880	regulation of blood vessel size
0.75	GO:0010469	regulation of receptor activity
0.67	GO:0003419	growth plate cartilage chondrocyte proliferation
0.66	GO:0003418	growth plate cartilage chondrocyte differentiation
0.66	GO:1900194	negative regulation of oocyte maturation
0.66	GO:0007168	receptor guanylyl cyclase signaling pathway
0.63	GO:0030823	regulation of cGMP metabolic process
0.62	GO:0051447	negative regulation of meiotic cell cycle
0.62	GO:0030814	regulation of cAMP metabolic process
0.61	GO:0006182	cGMP biosynthetic process

0.79	GO:0005179	hormone activity
0.60	GO:0051427	hormone receptor binding
0.41	GO:0090729	toxin activity
0.40	GO:0042803	protein homodimerization activity
0.39	GO:0008191	metalloendopeptidase inhibitor activity
0.35	GO:0005272	sodium channel activity
0.35	GO:0005267	potassium channel activity
0.34	GO:0060422	peptidyl-dipeptidase inhibitor activity

0.66	GO:0005576	extracellular region
0.47	GO:0043234	protein complex
0.42	GO:0030141	secretory granule
0.33	GO:0005829	cytosol
0.32	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|P55252|HPLN1_BOVIN
Hyaluronan and proteoglycan link protein 1
Search

HAPLN1

0.97	Hyaluronan and proteoglycan link protein 1

0.71	GO:0007155	cell adhesion
0.48	GO:0001501	skeletal system development
0.47	GO:0007417	central nervous system development
0.40	GO:0031101	fin regeneration
0.35	GO:0030198	extracellular matrix organization
0.35	GO:0002040	sprouting angiogenesis

0.83	GO:0005540	hyaluronic acid binding
0.48	GO:0005201	extracellular matrix structural constituent

0.53	GO:0005578	proteinaceous extracellular matrix
0.30	GO:0031224	intrinsic component of membrane

sp|P55270|SCNNA_BOVIN
Amiloride-sensitive sodium channel subunit alpha
Search

SCNN1A

0.97	Amiloride-sensitive sodium channel subunit alpha

0.77	GO:0035725	sodium ion transmembrane transport
0.61	GO:0055078	sodium ion homeostasis
0.60	GO:0050891	multicellular organismal water homeostasis
0.43	GO:0050909	sensory perception of taste
0.37	GO:0050896	response to stimulus
0.35	GO:0008217	regulation of blood pressure
0.34	GO:0016192	vesicle-mediated transport
0.34	GO:0016567	protein ubiquitination

0.85	GO:0015280	ligand-gated sodium channel activity
0.59	GO:0050699	WW domain binding
0.34	GO:0003779	actin binding
0.34	GO:0061630	ubiquitin protein ligase activity
0.33	GO:0008270	zinc ion binding

0.60	GO:0060170	ciliary membrane
0.58	GO:0034706	sodium channel complex
0.58	GO:0016324	apical plasma membrane
0.56	GO:0031514	motile cilium
0.55	GO:0070062	extracellular exosome
0.49	GO:0005887	integral component of plasma membrane
0.40	GO:0005737	cytoplasm
0.37	GO:0009897	external side of plasma membrane
0.36	GO:0015629	actin cytoskeleton
0.34	GO:0044430	cytoskeletal part

sp|P55803|MOG_BOVIN
Myelin-oligodendrocyte glycoprotein
Search

MOG

0.97	myelin-oligodendrocyte glycoprotein isoform X1

0.59	GO:0007155	cell adhesion
0.38	GO:0032502	developmental process
0.37	GO:0051593	response to folic acid
0.37	GO:0032501	multicellular organismal process
0.35	GO:0033993	response to lipid
0.34	GO:0051806	entry into cell of other organism involved in symbiotic interaction
0.34	GO:0044409	entry into host
0.34	GO:0019058	viral life cycle
0.34	GO:0050863	regulation of T cell activation
0.33	GO:0045621	positive regulation of lymphocyte differentiation

0.37	GO:0104005	hijacked molecular function
0.34	GO:0042608	T cell receptor binding

0.38	GO:0043209	myelin sheath
0.36	GO:0009986	cell surface
0.36	GO:0045121	membrane raft
0.34	GO:0071944	cell periphery
0.30	GO:0016021	integral component of membrane

sp|P55859|PNPH_BOVIN
Purine nucleoside phosphorylase
Search

PNP

0.46	Purine nucleoside phosphorylase

0.66	GO:0009116	nucleoside metabolic process
0.56	GO:0034418	urate biosynthetic process
0.55	GO:0070970	interleukin-2 secretion
0.54	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway
0.53	GO:0046638	positive regulation of alpha-beta T cell differentiation
0.52	GO:0042102	positive regulation of T cell proliferation
0.51	GO:0072526	pyridine-containing compound catabolic process
0.50	GO:1901658	glycosyl compound catabolic process
0.50	GO:0072523	purine-containing compound catabolic process
0.47	GO:0006955	immune response

0.78	GO:0004731	purine-nucleoside phosphorylase activity
0.56	GO:0002060	purine nucleobase binding
0.50	GO:0042301	phosphate ion binding
0.44	GO:0001882	nucleoside binding
0.40	GO:0008144	drug binding
0.39	GO:0047724	inosine nucleosidase activity
0.39	GO:0070635	nicotinamide riboside hydrolase activity

0.46	GO:0005829	cytosol
0.37	GO:0005856	cytoskeleton
0.36	GO:0070062	extracellular exosome
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen
0.35	GO:0005634	nucleus
0.30	GO:0044425	membrane part

0.78

EC:2.4.2.1

GO:0004731

sp|P55906|BGH3_BOVIN
Transforming growth factor-beta-induced protein ig-h3
Search

TGFBI

0.79	Transforming growth factor beta induced

0.78	GO:0008283	cell proliferation
0.71	GO:0007155	cell adhesion
0.57	GO:0030198	extracellular matrix organization
0.55	GO:0001525	angiogenesis
0.46	GO:0061061	muscle structure development
0.44	GO:0048513	animal organ development
0.43	GO:0030154	cell differentiation
0.41	GO:0071466	cellular response to xenobiotic stimulus
0.41	GO:0061448	connective tissue development
0.40	GO:0001501	skeletal system development

0.83	GO:0005178	integrin binding
0.83	GO:0050840	extracellular matrix binding
0.81	GO:0005518	collagen binding

0.55	GO:0005578	proteinaceous extracellular matrix
0.54	GO:0005802	trans-Golgi network
0.53	GO:0005615	extracellular space
0.41	GO:0044420	extracellular matrix component
0.36	GO:1903561	extracellular vesicle
0.30	GO:0031224	intrinsic component of membrane

sp|P55918|MFAP4_BOVIN
Microfibril-associated glycoprotein 4
Search

MFAP4

0.90	Microfibrillar-associated protein 4 type I

0.82	GO:0071493	cellular response to UV-B
0.81	GO:0009650	UV protection
0.81	GO:0048251	elastic fiber assembly
0.80	GO:0010712	regulation of collagen metabolic process
0.68	GO:0097435	supramolecular fiber organization
0.46	GO:0007155	cell adhesion
0.40	GO:0000165	MAPK cascade
0.38	GO:0071310	cellular response to organic substance
0.38	GO:0032501	multicellular organismal process
0.37	GO:0048856	anatomical structure development

0.40	GO:0004707	MAP kinase activity
0.37	GO:0005515	protein binding

0.84	GO:0071953	elastic fiber
0.80	GO:0001527	microfibril
0.68	GO:0005615	extracellular space
0.47	GO:1903561	extracellular vesicle
0.46	GO:0005578	proteinaceous extracellular matrix
0.36	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.40	EC:2.7.11.24	GO:0004707
0.40	KEGG:R00162	GO:0004707

sp|P55942|MT1H_BOVIN
Metallothionein-I, hippocampal
Search

0.75	Metallothionein-II, hippocampal

0.65	GO:0071294	cellular response to zinc ion
0.57	GO:0045926	negative regulation of growth
0.49	GO:0036018	cellular response to erythropoietin
0.48	GO:0071276	cellular response to cadmium ion
0.44	GO:0036015	response to interleukin-3
0.42	GO:0010273	detoxification of copper ion
0.42	GO:0007263	nitric oxide mediated signal transduction
0.41	GO:0035690	cellular response to drug
0.41	GO:0006882	cellular zinc ion homeostasis
0.39	GO:0071247	cellular response to chromate

0.54	GO:0046872	metal ion binding
0.36	GO:0005515	protein binding
0.35	GO:0008144	drug binding

0.55	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0005634	nucleus
0.37	GO:0005829	cytosol
0.36	GO:0005764	lysosome

sp|P55943|MT2H_BOVIN
Metallothionein-II, hippocampal
Search

0.74	Metallothionein-II, hippocampal

0.65	GO:0071294	cellular response to zinc ion
0.56	GO:0045926	negative regulation of growth
0.49	GO:0036018	cellular response to erythropoietin
0.47	GO:0071276	cellular response to cadmium ion
0.44	GO:0036015	response to interleukin-3
0.41	GO:0010273	detoxification of copper ion
0.41	GO:0035690	cellular response to drug
0.41	GO:0007263	nitric oxide mediated signal transduction
0.40	GO:0006882	cellular zinc ion homeostasis
0.39	GO:0071247	cellular response to chromate

0.54	GO:0046872	metal ion binding
0.36	GO:0005515	protein binding
0.35	GO:0008144	drug binding

0.55	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0005634	nucleus
0.37	GO:0005829	cytosol
0.36	GO:0005764	lysosome

sp|P56413|AGRP_BOVIN
Agouti-related protein
Search

AGRP

0.97	Agouti related neuropeptide

0.77	GO:0009755	hormone-mediated signaling pathway
0.64	GO:0060259	regulation of feeding behavior
0.61	GO:0008343	adult feeding behavior
0.60	GO:0007218	neuropeptide signaling pathway
0.57	GO:0010469	regulation of receptor activity
0.47	GO:0048520	positive regulation of behavior
0.44	GO:0048571	long-day photoperiodism
0.43	GO:0042755	eating behavior
0.43	GO:0060135	maternal process involved in female pregnancy
0.42	GO:0032868	response to insulin

0.72	GO:0005102	receptor binding
0.57	GO:0030545	receptor regulator activity

0.66	GO:0005576	extracellular region
0.62	GO:0005796	Golgi lumen
0.41	GO:0043025	neuronal cell body
0.36	GO:0031982	vesicle

sp|P56425|CTHL7_BOVIN
Cathelicidin-7
Search

0.95	Preprocathelicidin antimicrobial peptide

0.72	GO:0006952	defense response
0.60	GO:0009617	response to bacterium
0.47	GO:0044140	negative regulation of growth of symbiont on or near host surface
0.45	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.45	GO:0044130	negative regulation of growth of symbiont in host
0.44	GO:0051851	modification by host of symbiont morphology or physiology
0.44	GO:0031640	killing of cells of other organism
0.43	GO:0051818	disruption of cells of other organism involved in symbiotic interaction
0.38	GO:0019835	cytolysis
0.37	GO:0009620	response to fungus

0.33	GO:0005515	protein binding
0.32	GO:0046872	metal ion binding
0.32	GO:0003676	nucleic acid binding

0.66	GO:0005576	extracellular region
0.45	GO:0042581	specific granule
0.35	GO:1904724	tertiary granule lumen
0.34	GO:0034774	secretory granule lumen
0.33	GO:0042995	cell projection
0.30	GO:0016020	membrane

sp|P56449|OXYR_BOVIN
Oxytocin receptor
Search

OXTR

0.96	Oxytocin receptor

0.68	GO:0007186	G-protein coupled receptor signaling pathway
0.56	GO:0045777	positive regulation of blood pressure
0.49	GO:0001992	regulation of systemic arterial blood pressure by vasopressin
0.48	GO:0045907	positive regulation of vasoconstriction
0.47	GO:0042711	maternal behavior
0.46	GO:1901652	response to peptide
0.46	GO:0035176	social behavior
0.46	GO:0007595	lactation
0.45	GO:0007565	female pregnancy
0.44	GO:0009725	response to hormone

0.85	GO:0004990	oxytocin receptor activity
0.83	GO:0005000	vasopressin receptor activity
0.45	GO:0042277	peptide binding
0.39	GO:0042562	hormone binding
0.33	GO:0005515	protein binding

0.49	GO:0005886	plasma membrane
0.39	GO:0005902	microvillus
0.39	GO:0005913	cell-cell adherens junction
0.38	GO:0045177	apical part of cell
0.33	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|P56451|MC5R_BOVIN
Melanocortin receptor 5
Search

MC5R

0.97	Melanocortin receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.53	GO:0019933	cAMP-mediated signaling
0.43	GO:0060259	regulation of feeding behavior
0.42	GO:0030819	positive regulation of cAMP biosynthetic process
0.41	GO:0048521	negative regulation of behavior
0.41	GO:0097009	energy homeostasis
0.39	GO:0040008	regulation of growth
0.39	GO:0006112	energy reserve metabolic process
0.37	GO:0045475	locomotor rhythm
0.37	GO:0032922	circadian regulation of gene expression

0.84	GO:0004977	melanocortin receptor activity
0.38	GO:0042562	hormone binding
0.37	GO:0042923	neuropeptide binding
0.33	GO:0005515	protein binding

0.55	GO:0005886	plasma membrane
0.36	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|P56541|DNS2A_BOVIN
Deoxyribonuclease-2-alpha
Search

DNASE2

0.63	Deoxyribonuclease II alpha

0.60	GO:0000737	DNA catabolic process, endonucleolytic
0.57	GO:0030218	erythrocyte differentiation
0.51	GO:0030262	apoptotic nuclear changes
0.34	GO:2001256	regulation of store-operated calcium entry
0.33	GO:0043043	peptide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process
0.32	GO:0007165	signal transduction

0.84	GO:0004531	deoxyribonuclease II activity
0.34	GO:0043022	ribosome binding
0.34	GO:0005509	calcium ion binding
0.33	GO:0003735	structural constituent of ribosome
0.33	GO:0003677	DNA binding

0.42	GO:0005764	lysosome
0.37	GO:0070062	extracellular exosome
0.33	GO:0030176	integral component of endoplasmic reticulum membrane
0.33	GO:0005840	ribosome
0.33	GO:0005739	mitochondrion

0.84

EC:3.1.22.1

GO:0004531

sp|P56560|AOFB_BOVIN
Amine oxidase [flavin-containing] B
Search

MAOB

0.49	Amine oxidase [flavin-containing] B

0.52	GO:0055114	oxidation-reduction process
0.52	GO:0042420	dopamine catabolic process
0.41	GO:0042135	neurotransmitter catabolic process
0.39	GO:0014063	negative regulation of serotonin secretion
0.39	GO:0010269	response to selenium ion
0.39	GO:0045964	positive regulation of dopamine metabolic process
0.39	GO:0051412	response to corticosterone
0.39	GO:0010044	response to aluminum ion
0.38	GO:0045471	response to ethanol
0.37	GO:0032496	response to lipopolysaccharide

0.54	GO:0016491	oxidoreductase activity
0.36	GO:0042803	protein homodimerization activity
0.36	GO:0050660	flavin adenine dinucleotide binding
0.35	GO:0051378	serotonin binding

0.48	GO:0005739	mitochondrion
0.46	GO:0031967	organelle envelope
0.46	GO:0031090	organelle membrane
0.43	GO:0098805	whole membrane
0.41	GO:0019867	outer membrane
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.54

EC:1

GO:0016491

sp|P56602|PPOX_BOVIN
Protoporphyrinogen oxidase
Search

PPOX

0.53	Protoporphyrinogen oxidase

0.72	GO:0006782	protoporphyrinogen IX biosynthetic process
0.52	GO:0055114	oxidation-reduction process
0.37	GO:0042493	response to drug

0.80	GO:0070818	protoporphyrinogen oxidase activity
0.74	GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor
0.34	GO:0050660	flavin adenine dinucleotide binding
0.32	GO:0016874	ligase activity

0.60	GO:0031966	mitochondrial membrane
0.60	GO:0019866	organelle inner membrane
0.54	GO:0031300	intrinsic component of organelle membrane
0.35	GO:0005758	mitochondrial intermembrane space
0.30	GO:0016021	integral component of membrane

0.74

EC:1.3.3

GO:0016634

sp|P56651|ITIH2_BOVIN
Inter-alpha-trypsin inhibitor heavy chain H2 (Fragments)
Search

0.11	Inter-alpha-trypsin inhibitor heavy chain H2 (Fragments)

0.85	GO:0030212	hyaluronan metabolic process
0.76	GO:0010951	negative regulation of endopeptidase activity
0.36	GO:0043687	post-translational protein modification

0.79

GO:0004867

serine-type endopeptidase inhibitor activity

0.41	GO:0005576	extracellular region
0.37	GO:0031982	vesicle
0.37	GO:0005788	endoplasmic reticulum lumen

sp|P56652|ITIH3_BOVIN
Inter-alpha-trypsin inhibitor heavy chain H3
Search

ITIH3

0.95	Inter-alpha-trypsin inhibitor heavy chain 3

0.85	GO:0030212	hyaluronan metabolic process
0.76	GO:0010951	negative regulation of endopeptidase activity
0.36	GO:0002576	platelet degranulation
0.34	GO:0006953	acute-phase response
0.33	GO:0034097	response to cytokine

0.78	GO:0004867	serine-type endopeptidase inhibitor activity
0.33	GO:0005509	calcium ion binding

0.40	GO:0005576	extracellular region
0.37	GO:0031982	vesicle
0.34	GO:0012505	endomembrane system
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.33	GO:0044444	cytoplasmic part
0.30	GO:0031224	intrinsic component of membrane

sp|P56658|ADA_BOVIN
Adenosine deaminase
Search

ADA

0.51	Adenosine deaminase

0.65	GO:0009168	purine ribonucleoside monophosphate biosynthetic process
0.64	GO:0060169	negative regulation of adenosine receptor signaling pathway
0.61	GO:0046111	xanthine biosynthetic process
0.61	GO:0060407	negative regulation of penile erection
0.61	GO:0006157	deoxyadenosine catabolic process
0.61	GO:0006154	adenosine catabolic process
0.61	GO:0046103	inosine biosynthetic process
0.60	GO:0070256	negative regulation of mucus secretion
0.60	GO:0002636	positive regulation of germinal center formation
0.59	GO:0002314	germinal center B cell differentiation

0.72	GO:0019239	deaminase activity
0.61	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
0.47	GO:0008270	zinc ion binding
0.37	GO:0001883	purine nucleoside binding
0.35	GO:0005515	protein binding

0.57	GO:0009897	external side of plasma membrane
0.54	GO:0005764	lysosome
0.50	GO:0005829	cytosol
0.44	GO:0060205	cytoplasmic vesicle lumen
0.41	GO:0030054	cell junction
0.41	GO:0032839	dendrite cytoplasm
0.39	GO:0043025	neuronal cell body
0.38	GO:0005615	extracellular space

0.61

EC:3.5.4

GO:0016814

sp|P56701|PSMD2_BOVIN
26S proteasome non-ATPase regulatory subunit 2
Search

PSMD2

0.91	26S proteasome non-ATPase regulatory subunit 2

0.78	GO:0042176	regulation of protein catabolic process
0.69	GO:0050790	regulation of catalytic activity
0.45	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation
0.35	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0070498	interleukin-1-mediated signaling pathway

0.70	GO:0030234	enzyme regulator activity
0.42	GO:0004175	endopeptidase activity
0.34	GO:0005515	protein binding
0.33	GO:0008237	metallopeptidase activity

0.73	GO:1905369	endopeptidase complex
0.60	GO:0043234	protein complex
0.45	GO:0005622	intracellular
0.38	GO:0043227	membrane-bounded organelle
0.36	GO:0043230	extracellular organelle
0.35	GO:0005615	extracellular space
0.33	GO:0012505	endomembrane system
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0044422	organelle part
0.30	GO:0016020	membrane

sp|P56717|OREX_BOVIN
Orexin-A
Search

0.10

Orexin-A

0.84	GO:0007631	feeding behavior
0.80	GO:0007218	neuropeptide signaling pathway
0.47	GO:0051970	negative regulation of transmission of nerve impulse
0.46	GO:0051971	positive regulation of transmission of nerve impulse
0.45	GO:0043267	negative regulation of potassium ion transport
0.45	GO:0001659	temperature homeostasis
0.45	GO:0046928	regulation of neurotransmitter secretion
0.44	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.44	GO:0051928	positive regulation of calcium ion transport
0.44	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway

0.48	GO:0042324	hypocretin receptor binding
0.44	GO:0005184	neuropeptide hormone activity
0.36	GO:0005249	voltage-gated potassium channel activity
0.35	GO:0000155	phosphorelay sensor kinase activity

0.63	GO:0048471	perinuclear region of cytoplasm
0.59	GO:0005791	rough endoplasmic reticulum
0.46	GO:0045202	synapse
0.45	GO:0031410	cytoplasmic vesicle
0.43	GO:0030054	cell junction
0.40	GO:0097458	neuron part
0.39	GO:0044297	cell body
0.39	GO:0045177	apical part of cell
0.38	GO:0120025	plasma membrane bounded cell projection
0.35	GO:0005576	extracellular region

0.35

EC:2.7.3

GO:0000155

sp|P56722|PTPRN_BOVIN
Receptor-type tyrosine-protein phosphatase-like N
Search

PTPRN

0.92	Protein tyrosine phosphatase receptor type N

0.76	GO:1904692	positive regulation of type B pancreatic cell proliferation
0.75	GO:1990502	dense core granule maturation
0.71	GO:0030073	insulin secretion
0.62	GO:0045944	positive regulation of transcription by RNA polymerase II
0.62	GO:0000302	response to reactive oxygen species
0.55	GO:0035335	peptidyl-tyrosine dephosphorylation
0.39	GO:0051591	response to cAMP
0.39	GO:0043627	response to estrogen
0.39	GO:0009749	response to glucose
0.38	GO:0032868	response to insulin

0.70	GO:0030507	spectrin binding
0.65	GO:0044389	ubiquitin-like protein ligase binding
0.60	GO:0008134	transcription factor binding
0.55	GO:0004725	protein tyrosine phosphatase activity
0.37	GO:0051020	GTPase binding

0.52	GO:0005634	nucleus
0.39	GO:0043679	axon terminus
0.38	GO:0043025	neuronal cell body
0.38	GO:0030141	secretory granule
0.37	GO:0005768	endosome
0.37	GO:0005794	Golgi apparatus
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.55

EC:3.1.3.48

GO:0004725

sp|P56830|IFNT2_BOVIN
Interferon tau-2
Search

0.97	Interferon tau

0.78	GO:0051607	defense response to virus
0.76	GO:0010469	regulation of receptor activity
0.56	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein
0.56	GO:0002323	natural killer cell activation involved in immune response
0.55	GO:0042100	B cell proliferation
0.55	GO:0002286	T cell activation involved in immune response
0.54	GO:0043330	response to exogenous dsRNA
0.54	GO:0030183	B cell differentiation
0.53	GO:0002250	adaptive immune response
0.52	GO:0006959	humoral immune response

0.81	GO:0005125	cytokine activity
0.79	GO:0005126	cytokine receptor binding
0.50	GO:0032403	protein complex binding
0.45	GO:0005179	hormone activity

0.73	GO:0005615	extracellular space
0.31	GO:0005622	intracellular
0.30	GO:0016020	membrane

sp|P56831|IFNT3_BOVIN
Interferon tau-3
Search

IFNT

0.97	Interferon tau

0.78	GO:0051607	defense response to virus
0.76	GO:0010469	regulation of receptor activity
0.56	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein
0.56	GO:0002323	natural killer cell activation involved in immune response
0.55	GO:0042100	B cell proliferation
0.54	GO:0002286	T cell activation involved in immune response
0.54	GO:0043330	response to exogenous dsRNA
0.54	GO:0030183	B cell differentiation
0.53	GO:0002250	adaptive immune response
0.52	GO:0006959	humoral immune response

0.81	GO:0005125	cytokine activity
0.79	GO:0005126	cytokine receptor binding
0.49	GO:0032403	protein complex binding
0.45	GO:0005179	hormone activity

0.73	GO:0005615	extracellular space
0.31	GO:0005622	intracellular
0.30	GO:0016020	membrane

sp|P56965|DDAH1_BOVIN
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1
Search

DDAH1

0.89	Dimethylarginine dimethylaminohydrolase I

0.85	GO:0000052	citrulline metabolic process
0.85	GO:0045429	positive regulation of nitric oxide biosynthetic process
0.76	GO:0006527	arginine catabolic process
0.58	GO:0043116	negative regulation of vascular permeability
0.58	GO:1900038	negative regulation of cellular response to hypoxia
0.55	GO:0003073	regulation of systemic arterial blood pressure
0.53	GO:0008285	negative regulation of cell proliferation
0.40	GO:0045766	positive regulation of angiogenesis
0.38	GO:0017014	protein nitrosylation
0.37	GO:0006809	nitric oxide biosynthetic process

0.85	GO:0016403	dimethylargininase activity
0.39	GO:0016597	amino acid binding
0.35	GO:0046872	metal ion binding

0.44	GO:0005739	mitochondrion
0.37	GO:0070062	extracellular exosome
0.35	GO:0005829	cytosol
0.33	GO:0005815	microtubule organizing center

0.85

EC:3.5.3.18

GO:0016403

sp|P56966|GGPPS_BOVIN
Geranylgeranyl pyrophosphate synthase
Search

GGPS1

0.53	Geranylgeranyl pyrophosphate synthetase

0.69	GO:0008299	isoprenoid biosynthetic process
0.41	GO:0033383	geranyl diphosphate metabolic process
0.41	GO:0033385	geranylgeranyl diphosphate metabolic process
0.40	GO:0045338	farnesyl diphosphate metabolic process
0.37	GO:0008654	phospholipid biosynthetic process
0.35	GO:0045540	regulation of cholesterol biosynthetic process
0.35	GO:0006695	cholesterol biosynthetic process

0.54	GO:0004337	geranyltranstransferase activity
0.52	GO:0004311	farnesyltranstransferase activity
0.50	GO:0042802	identical protein binding
0.40	GO:0004161	dimethylallyltranstransferase activity
0.34	GO:0046872	metal ion binding

0.34

GO:0005829

cytosol

0.54	EC:2.5.1.10	GO:0004337
0.54	KEGG:R02003	GO:0004337

sp|P56982|TM14A_BOVIN
Transmembrane protein 14A
Search

TMEM14A

0.64	Transmembrane protein 14A

0.62	GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
0.40	GO:0070453	regulation of heme biosynthetic process
0.38	GO:0030218	erythrocyte differentiation
0.35	GO:0006915	apoptotic process
0.33	GO:0006629	lipid metabolic process

0.34	GO:0005515	protein binding
0.33	GO:0008081	phosphoric diester hydrolase activity
0.33	GO:0016746	transferase activity, transferring acyl groups
0.32	GO:0003676	nucleic acid binding

0.51	GO:0005789	endoplasmic reticulum membrane
0.47	GO:0031966	mitochondrial membrane
0.35	GO:0019866	organelle inner membrane
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0008081

sp|P57695|GLRA1_BOVIN
Glycine receptor subunit alpha-1
Search

GLRA1

0.96	Glycine receptor subunit alpha-1

0.71	GO:0060079	excitatory postsynaptic potential
0.69	GO:1902476	chloride transmembrane transport
0.59	GO:0060012	synaptic transmission, glycinergic
0.59	GO:0051970	negative regulation of transmission of nerve impulse
0.58	GO:0071294	cellular response to zinc ion
0.58	GO:0071361	cellular response to ethanol
0.57	GO:2000344	positive regulation of acrosome reaction
0.57	GO:0060080	inhibitory postsynaptic potential
0.57	GO:0060013	righting reflex
0.57	GO:0002087	regulation of respiratory gaseous exchange by neurological system process

0.85	GO:0016594	glycine binding
0.79	GO:0016934	extracellularly glycine-gated chloride channel activity
0.76	GO:0022824	transmitter-gated ion channel activity
0.69	GO:0004888	transmembrane signaling receptor activity
0.60	GO:0043210	alkanesulfonate binding
0.45	GO:0008270	zinc ion binding
0.36	GO:0042802	identical protein binding

0.70	GO:0045211	postsynaptic membrane
0.66	GO:0005887	integral component of plasma membrane
0.56	GO:0060077	inhibitory synapse
0.54	GO:0043025	neuronal cell body
0.53	GO:0009897	external side of plasma membrane
0.52	GO:0043005	neuron projection
0.43	GO:0034707	chloride channel complex
0.42	GO:0043231	intracellular membrane-bounded organelle
0.40	GO:0120038	plasma membrane bounded cell projection part
0.39	GO:0030054	cell junction

sp|P57709|AT2C1_BOVIN
Calcium-transporting ATPase type 2C member 1
Search

ATP2C1

0.55	Calcium-transporting ATPase

0.76	GO:0070588	calcium ion transmembrane transport
0.68	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.56	GO:0032472	Golgi calcium ion transport
0.56	GO:0032468	Golgi calcium ion homeostasis
0.53	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.51	GO:0008544	epidermis development
0.49	GO:0031532	actin cytoskeleton reorganization
0.40	GO:0030026	cellular manganese ion homeostasis
0.40	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.40	GO:0071421	manganese ion transmembrane transport

0.79	GO:0005388	calcium-transporting ATPase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0015410	manganese-transporting ATPase activity
0.38	GO:0030145	manganese ion binding
0.37	GO:0005509	calcium ion binding
0.36	GO:0004871	signal transducer activity
0.34	GO:0009013	succinate-semialdehyde dehydrogenase [NAD(P)+] activity

0.50	GO:0005802	trans-Golgi network
0.48	GO:0000139	Golgi membrane
0.34	GO:0030141	secretory granule
0.34	GO:0031985	Golgi cisterna
0.34	GO:0030133	transport vesicle
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.79

EC:3.6.3.8

GO:0005388

sp|P58073|PTHR_BOVIN
Parathyroid hormone-related protein
Search

PTHLH

0.97	Parathyroid hormone like hormone

0.85	GO:0032330	regulation of chondrocyte differentiation
0.75	GO:0010469	regulation of receptor activity
0.61	GO:0061037	negative regulation of cartilage development
0.60	GO:0030819	positive regulation of cAMP biosynthetic process
0.60	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.56	GO:0045596	negative regulation of cell differentiation
0.56	GO:0001501	skeletal system development
0.52	GO:0002076	osteoblast development
0.44	GO:0060255	regulation of macromolecule metabolic process
0.41	GO:0042127	regulation of cell proliferation

0.79	GO:0005179	hormone activity
0.64	GO:0051428	peptide hormone receptor binding

0.66	GO:0005576	extracellular region
0.52	GO:0005794	Golgi apparatus
0.51	GO:0005654	nucleoplasm
0.51	GO:0005829	cytosol

sp|P58108|AAKG1_BOVIN
5'-AMP-activated protein kinase subunit gamma-1
Search

PRKAG1

0.96	5'-AMP-activated protein kinase gamma-1 non-catalytic subunit variant 1

0.55	GO:0016310	phosphorylation
0.51	GO:0010604	positive regulation of macromolecule metabolic process
0.50	GO:0051170	nuclear import
0.46	GO:0036211	protein modification process
0.44	GO:0006110	regulation of glycolytic process
0.43	GO:0044267	cellular protein metabolic process
0.42	GO:0010468	regulation of gene expression
0.41	GO:0010799	regulation of peptidyl-threonine phosphorylation
0.41	GO:0019217	regulation of fatty acid metabolic process
0.41	GO:0033674	positive regulation of kinase activity

0.58	GO:0016301	kinase activity
0.54	GO:0019901	protein kinase binding
0.46	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.44	GO:0140096	catalytic activity, acting on a protein
0.44	GO:0008607	phosphorylase kinase regulator activity
0.44	GO:0043531	ADP binding
0.43	GO:0008603	cAMP-dependent protein kinase regulator activity
0.42	GO:0004862	cAMP-dependent protein kinase inhibitor activity
0.42	GO:0016208	AMP binding
0.41	GO:0030295	protein kinase activator activity

0.46	GO:0031588	nucleotide-activated protein kinase complex
0.46	GO:0005634	nucleus
0.40	GO:0070013	intracellular organelle lumen
0.39	GO:0034708	methyltransferase complex
0.37	GO:0044446	intracellular organelle part
0.37	GO:0070062	extracellular exosome
0.36	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.46

GO:0016773

sp|P58126|KCNQ3_BOVIN
Potassium voltage-gated channel subfamily KQT member 3
Search

KCNQ3

0.58	Voltage-gated potassium channel

0.72	GO:0071805	potassium ion transmembrane transport
0.61	GO:0060081	membrane hyperpolarization
0.40	GO:0034765	regulation of ion transmembrane transport
0.36	GO:0007268	chemical synaptic transmission
0.36	GO:0061548	ganglion development
0.36	GO:0014003	oligodendrocyte development
0.36	GO:0071242	cellular response to ammonium ion
0.34	GO:0042472	inner ear morphogenesis
0.34	GO:0007605	sensory perception of sound

0.77	GO:0005249	voltage-gated potassium channel activity
0.55	GO:0005516	calmodulin binding
0.36	GO:0044325	ion channel binding
0.35	GO:0031625	ubiquitin protein ligase binding
0.35	GO:0019901	protein kinase binding

0.77	GO:0008076	voltage-gated potassium channel complex
0.60	GO:0043194	axon initial segment
0.60	GO:0033268	node of Ranvier
0.53	GO:0009986	cell surface
0.35	GO:0043025	neuronal cell body
0.35	GO:0030425	dendrite
0.35	GO:0045121	membrane raft

sp|P58280|MT1_BOVIN
Metallothionein-1
Search

0.75	Metallothionein-II, hippocampal

0.64	GO:0071294	cellular response to zinc ion
0.55	GO:0045926	negative regulation of growth
0.49	GO:0036018	cellular response to erythropoietin
0.46	GO:0071276	cellular response to cadmium ion
0.44	GO:0036015	response to interleukin-3
0.42	GO:0010273	detoxification of copper ion
0.42	GO:0007263	nitric oxide mediated signal transduction
0.41	GO:0035690	cellular response to drug
0.41	GO:0006882	cellular zinc ion homeostasis
0.40	GO:0071247	cellular response to chromate

0.54	GO:0046872	metal ion binding
0.36	GO:0008144	drug binding
0.35	GO:0005515	protein binding

0.54	GO:0048471	perinuclear region of cytoplasm
0.46	GO:0005634	nucleus
0.37	GO:0005764	lysosome
0.36	GO:0005829	cytosol

sp|P58351|GTR2_BOVIN
Solute carrier family 2, facilitated glucose transporter member 2
Search

SLC2A2

0.95	Faciliated glucose transporter 2

0.70	GO:1904659	glucose transmembrane transport
0.63	GO:0070837	dehydroascorbic acid transport
0.46	GO:0043434	response to peptide hormone
0.46	GO:0046323	glucose import
0.46	GO:1901653	cellular response to peptide
0.44	GO:0032870	cellular response to hormone stimulus
0.43	GO:0001889	liver development
0.42	GO:0007420	brain development
0.40	GO:0010021	amylopectin biosynthetic process
0.39	GO:0050873	brown fat cell differentiation

0.70	GO:0005355	glucose transmembrane transporter activity
0.63	GO:0033300	dehydroascorbic acid transmembrane transporter activity
0.36	GO:0005158	insulin receptor binding

0.58	GO:0005903	brush border
0.57	GO:0016324	apical plasma membrane
0.54	GO:0005911	cell-cell junction
0.40	GO:0005737	cytoplasm
0.39	GO:0042383	sarcolemma
0.38	GO:0009897	external side of plasma membrane
0.38	GO:0070062	extracellular exosome
0.38	GO:0045121	membrane raft
0.38	GO:0097708	intracellular vesicle
0.38	GO:0012506	vesicle membrane

sp|P58352|GTR3_BOVIN
Solute carrier family 2, facilitated glucose transporter member 3
Search

SLC2A3

0.76	Glucose transporter

0.72	GO:1904659	glucose transmembrane transport
0.54	GO:0070837	dehydroascorbic acid transport
0.38	GO:0032868	response to insulin
0.37	GO:0071548	response to dexamethasone
0.37	GO:1904016	response to Thyroglobulin triiodothyronine
0.37	GO:0042149	cellular response to glucose starvation
0.36	GO:0019852	L-ascorbic acid metabolic process
0.36	GO:0021987	cerebral cortex development
0.35	GO:0044703	multi-organism reproductive process
0.35	GO:0043312	neutrophil degranulation

0.72	GO:0005355	glucose transmembrane transporter activity
0.54	GO:0033300	dehydroascorbic acid transmembrane transporter activity
0.44	GO:0005536	glucose binding
0.37	GO:0043621	protein self-association
0.36	GO:0033222	xylose binding
0.36	GO:0042802	identical protein binding
0.35	GO:0016936	galactoside binding
0.35	GO:0019900	kinase binding
0.34	GO:0042910	xenobiotic transmembrane transporter activity

0.50	GO:0002080	acrosomal membrane
0.41	GO:0005886	plasma membrane
0.38	GO:0001939	female pronucleus
0.37	GO:0045121	membrane raft
0.37	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.37	GO:0030496	midbody
0.36	GO:0030864	cortical actin cytoskeleton
0.36	GO:0045177	apical part of cell
0.35	GO:0101003	ficolin-1-rich granule membrane

sp|P58353|GTR5_BOVIN
Solute carrier family 2, facilitated glucose transporter member 5
Search

SLC2A5

0.93	Solute carrier family 2, facilitated glucose transporter member 5

0.62	GO:0008643	carbohydrate transport
0.56	GO:0071332	cellular response to fructose stimulus
0.55	GO:0055085	transmembrane transport
0.52	GO:0003044	regulation of systemic arterial blood pressure mediated by a chemical signal
0.47	GO:0098657	import into cell
0.35	GO:0050892	intestinal absorption
0.35	GO:0043312	neutrophil degranulation
0.33	GO:0005975	carbohydrate metabolic process

0.62	GO:0005353	fructose transmembrane transporter activity
0.43	GO:0070061	fructose binding
0.36	GO:0005355	glucose transmembrane transporter activity

0.51	GO:0016324	apical plasma membrane
0.45	GO:0005887	integral component of plasma membrane
0.43	GO:0042383	sarcolemma
0.36	GO:0070062	extracellular exosome
0.36	GO:0035579	specific granule membrane

sp|P58354|GTR8_BOVIN
Solute carrier family 2, facilitated glucose transporter member 8
Search

SLC2A8

0.95	Glucose transporter type 8

0.63	GO:0008643	carbohydrate transport
0.55	GO:0008286	insulin receptor signaling pathway
0.54	GO:0055085	transmembrane transport
0.53	GO:0001666	response to hypoxia
0.41	GO:0007141	male meiosis I
0.40	GO:0015992	proton transport
0.34	GO:0005975	carbohydrate metabolic process
0.34	GO:0061024	membrane organization
0.32	GO:0044281	small molecule metabolic process

0.56	GO:0022857	transmembrane transporter activity
0.53	GO:0005536	glucose binding

0.46	GO:0005887	integral component of plasma membrane
0.40	GO:0008021	synaptic vesicle
0.39	GO:0030659	cytoplasmic vesicle membrane
0.37	GO:0005765	lysosomal membrane
0.35	GO:0030136	clathrin-coated vesicle

sp|P58754|LY96_BOVIN
Lymphocyte antigen 96
Search

LY96

0.97	Myeloid differentiation factor 2

0.87	GO:0032497	detection of lipopolysaccharide
0.85	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway
0.85	GO:0031663	lipopolysaccharide-mediated signaling pathway
0.85	GO:0034142	toll-like receptor 4 signaling pathway
0.85	GO:0032760	positive regulation of tumor necrosis factor production
0.50	GO:0006954	inflammatory response
0.50	GO:0045087	innate immune response
0.44	GO:0034128	negative regulation of MyD88-independent toll-like receptor signaling pathway
0.43	GO:0035666	TRIF-dependent toll-like receptor signaling pathway
0.42	GO:0006968	cellular defense response

0.85	GO:0001875	lipopolysaccharide receptor activity
0.41	GO:0015026	coreceptor activity
0.39	GO:0005515	protein binding

0.85	GO:0046696	lipopolysaccharide receptor complex
0.67	GO:0031226	intrinsic component of plasma membrane
0.48	GO:0005615	extracellular space
0.40	GO:0010008	endosome membrane

sp|P58874|OPT_BOVIN
Opticin
Search

OPTC

0.97	Dermatan sulfate proteoglycan 3

0.63	GO:0007409	axonogenesis
0.53	GO:0016525	negative regulation of angiogenesis
0.44	GO:0022617	extracellular matrix disassembly
0.40	GO:0007565	female pregnancy

0.49	GO:0005201	extracellular matrix structural constituent
0.38	GO:0005539	glycosaminoglycan binding
0.38	GO:0005515	protein binding

0.73	GO:0005578	proteinaceous extracellular matrix
0.59	GO:0005615	extracellular space
0.30	GO:0044425	membrane part

sp|P58875|S14L2_BOVIN
SEC14-like protein 2
Search

SEC14L3

0.84	Putative phosphatidylinositol transfer protein sec14

0.54	GO:0045540	regulation of cholesterol biosynthetic process
0.48	GO:0090205	positive regulation of cholesterol metabolic process
0.47	GO:0010893	positive regulation of steroid biosynthetic process
0.47	GO:1902932	positive regulation of alcohol biosynthetic process
0.46	GO:0006351	transcription, DNA-templated
0.45	GO:1903506	regulation of nucleic acid-templated transcription
0.45	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.45	GO:0010468	regulation of gene expression
0.42	GO:1902680	positive regulation of RNA biosynthetic process
0.42	GO:0043085	positive regulation of catalytic activity

0.60	GO:0008289	lipid binding
0.49	GO:0008431	vitamin E binding
0.43	GO:0008047	enzyme activator activity
0.41	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups
0.38	GO:0005515	protein binding
0.37	GO:0043168	anion binding

0.61	GO:0005829	cytosol
0.57	GO:0070062	extracellular exosome
0.56	GO:0005634	nucleus

0.41

EC:2.5 EC:2.5.1

GO:0016765

sp|P59760|GLYL_BOVIN
Glycolactin (Fragments)
Search

0.56	Glycolactin (Fragments)

0.78	GO:0051607	defense response to virus
0.76	GO:0017148	negative regulation of translation
0.69	GO:0098869	cellular oxidant detoxification
0.64	GO:0090305	nucleic acid phosphodiester bond hydrolysis

0.69	GO:0016209	antioxidant activity
0.66	GO:0004519	endonuclease activity

0.66

GO:0005576

extracellular region

sp|P59761|LGEN_BOVIN
Lactogenin (Fragments)
Search

0.44	Lactogenin (Fragments)

0.85	GO:0050691	regulation of defense response to virus by host
0.64	GO:0090305	nucleic acid phosphodiester bond hydrolysis

0.66	GO:0004519	endonuclease activity
0.51	GO:0003676	nucleic acid binding

0.66

GO:0005576

extracellular region

sp|P59837|RDH12_BOVIN
Retinol dehydrogenase 12
Search

RDH12

0.77	Androgen-regulated short-chain dehydrogenase/reductase 1

0.81	GO:0042572	retinol metabolic process
0.69	GO:0016062	adaptation of rhodopsin mediated signaling
0.66	GO:0042574	retinal metabolic process
0.49	GO:0055114	oxidation-reduction process
0.41	GO:0007601	visual perception
0.38	GO:0045494	photoreceptor cell maintenance
0.36	GO:0006886	intracellular protein transport
0.36	GO:0016192	vesicle-mediated transport

0.71	GO:0004745	retinol dehydrogenase activity
0.69	GO:0052650	NADP-retinol dehydrogenase activity
0.36	GO:0004022	alcohol dehydrogenase (NAD) activity
0.35	GO:0016630	protochlorophyllide reductase activity
0.35	GO:0005515	protein binding

0.66	GO:0001917	photoreceptor inner segment
0.42	GO:0042622	photoreceptor outer segment membrane
0.41	GO:0005622	intracellular
0.37	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.30	GO:0016021	integral component of membrane

0.71	EC:1.1.1.105	GO:0004745
0.69	KEGG:R08379	GO:0052650

sp|P60316|HOOK3_BOVIN
Protein Hook homolog 3 (Fragment)
Search

sp|P60519|GBRL2_BOVIN
Gamma-aminobutyric acid receptor-associated protein-like 2
Search

GABARAPL2

0.97	Gamma-aminobutyric acid receptor-associated protein 2

0.77	GO:0006914	autophagy
0.53	GO:1901799	negative regulation of proteasomal protein catabolic process
0.49	GO:0006995	cellular response to nitrogen starvation
0.49	GO:0061726	mitochondrion disassembly
0.48	GO:0007033	vacuole organization
0.45	GO:0070925	organelle assembly
0.37	GO:0048193	Golgi vesicle transport
0.37	GO:0015031	protein transport
0.36	GO:0032781	positive regulation of ATPase activity
0.35	GO:0032258	protein localization by the Cvt pathway

0.51	GO:0031625	ubiquitin protein ligase binding
0.38	GO:0030957	Tat protein binding
0.36	GO:0051117	ATPase binding
0.36	GO:0000149	SNARE binding
0.35	GO:0008429	phosphatidylethanolamine binding
0.35	GO:0031386	protein tag
0.35	GO:0050811	GABA receptor binding
0.34	GO:0048487	beta-tubulin binding
0.34	GO:0008017	microtubule binding
0.33	GO:0004252	serine-type endopeptidase activity

0.57	GO:0000421	autophagosome membrane
0.49	GO:0000139	Golgi membrane
0.44	GO:0005829	cytosol
0.37	GO:0031410	cytoplasmic vesicle
0.36	GO:0120095	vacuole-isolation membrane contact site
0.35	GO:0000407	phagophore assembly site
0.35	GO:0000329	fungal-type vacuole membrane
0.34	GO:0019898	extrinsic component of membrane
0.34	GO:0005739	mitochondrion

0.33

GO:0004252

sp|P60661|MYL6_BOVIN
Myosin light polypeptide 6
Search

MYL6

0.93	Smooth muscle myosin essential light chain

0.42	GO:0030049	muscle filament sliding
0.39	GO:0061061	muscle structure development
0.39	GO:0014706	striated muscle tissue development
0.38	GO:0048513	animal organ development
0.34	GO:0031032	actomyosin structure organization
0.34	GO:0010927	cellular component assembly involved in morphogenesis
0.34	GO:0048468	cell development
0.34	GO:0097435	supramolecular fiber organization
0.33	GO:0070925	organelle assembly
0.33	GO:0051301	cell division

0.70	GO:0005509	calcium ion binding
0.50	GO:0008307	structural constituent of muscle
0.42	GO:0030898	actin-dependent ATPase activity
0.38	GO:0003774	motor activity
0.35	GO:0005515	protein binding
0.34	GO:0043531	ADP binding
0.33	GO:0044877	macromolecular complex binding
0.33	GO:0000287	magnesium ion binding
0.33	GO:0003735	structural constituent of ribosome

0.51	GO:0016461	unconventional myosin complex
0.48	GO:0005903	brush border
0.39	GO:0070062	extracellular exosome
0.38	GO:0031012	extracellular matrix
0.37	GO:0005829	cytosol
0.36	GO:0005859	muscle myosin complex
0.35	GO:0097513	myosin II filament
0.34	GO:0042641	actomyosin
0.33	GO:0005840	ribosome
0.30	GO:0016020	membrane

sp|P60712|ACTB_BOVIN
Actin, cytoplasmic 1
Search

ACTB

0.64	Beta-actin variant 2

0.53	GO:0098974	postsynaptic actin cytoskeleton organization
0.52	GO:0072749	cellular response to cytochalasin B
0.49	GO:0032091	negative regulation of protein binding
0.46	GO:0045214	sarcomere organization
0.46	GO:0071346	cellular response to interferon-gamma
0.44	GO:0048870	cell motility
0.39	GO:0070527	platelet aggregation
0.39	GO:0001895	retina homeostasis
0.37	GO:0021762	substantia nigra development
0.37	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis

0.53	GO:0098973	structural constituent of postsynaptic actin cytoskeleton
0.51	GO:0030554	adenyl nucleotide binding
0.51	GO:0030957	Tat protein binding
0.51	GO:0050998	nitric-oxide synthase binding
0.50	GO:0097367	carbohydrate derivative binding
0.50	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0008144	drug binding
0.50	GO:0042802	identical protein binding
0.49	GO:0019894	kinesin binding
0.49	GO:0005522	profilin binding

0.75	GO:0097433	dense body
0.70	GO:0005925	focal adhesion
0.61	GO:0005856	cytoskeleton
0.53	GO:0043209	myelin sheath
0.50	GO:0005886	plasma membrane
0.47	GO:0035267	NuA4 histone acetyltransferase complex
0.47	GO:0036464	cytoplasmic ribonucleoprotein granule
0.47	GO:0070062	extracellular exosome
0.46	GO:0044448	cell cortex part
0.45	GO:0005829	cytosol

sp|P60902|S10AA_BOVIN
Protein S100-A10
Search

S100A10

0.97	S100 calcium binding protein A10

0.56	GO:0051894	positive regulation of focal adhesion assembly
0.56	GO:0051290	protein heterotetramerization
0.55	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading
0.55	GO:0051496	positive regulation of stress fiber assembly
0.55	GO:0001765	membrane raft assembly
0.53	GO:0072659	protein localization to plasma membrane
0.53	GO:0006900	vesicle budding from membrane
0.51	GO:0051099	positive regulation of binding
0.50	GO:0043547	positive regulation of GTPase activity
0.46	GO:0042127	regulation of cell proliferation

0.67	GO:0005509	calcium ion binding
0.54	GO:0044325	ion channel binding
0.51	GO:0042803	protein homodimerization activity
0.50	GO:0048306	calcium-dependent protein binding
0.36	GO:0008289	lipid binding
0.33	GO:0003723	RNA binding
0.32	GO:0046914	transition metal ion binding

0.52	GO:0045121	membrane raft
0.48	GO:0019897	extrinsic component of plasma membrane
0.46	GO:0005576	extracellular region
0.37	GO:0005783	endoplasmic reticulum
0.36	GO:0031982	vesicle
0.35	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|P60984|GMFB_BOVIN
Glia maturation factor beta
Search

GMFB

0.91	Glia maturation factor gamma

0.85	GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation
0.64	GO:2000249	regulation of actin cytoskeleton reorganization
0.53	GO:0071846	actin filament debranching
0.52	GO:0007612	learning
0.51	GO:0007626	locomotory behavior
0.41	GO:0010469	regulation of receptor activity
0.36	GO:0042325	regulation of phosphorylation
0.36	GO:0051348	negative regulation of transferase activity
0.35	GO:0031400	negative regulation of protein modification process
0.35	GO:0010563	negative regulation of phosphorus metabolic process

0.85	GO:0071933	Arp2/3 complex binding
0.73	GO:0003779	actin binding
0.42	GO:0008083	growth factor activity
0.37	GO:0019207	kinase regulator activity
0.35	GO:0008047	enzyme activator activity
0.35	GO:0004857	enzyme inhibitor activity
0.33	GO:0004871	signal transducer activity

0.45	GO:0005622	intracellular
0.35	GO:0031983	vesicle lumen
0.33	GO:0012505	endomembrane system
0.33	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

sp|P60986|PIP_BOVIN
Prolactin-inducible protein homolog
Search

PIP

0.97	Prolactin inducted protein (Fragment)

0.77	GO:0070233	negative regulation of T cell apoptotic process
0.75	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste
0.63	GO:0010628	positive regulation of gene expression
0.54	GO:0006508	proteolysis

0.79	GO:0019864	IgG binding
0.61	GO:0070001	aspartic-type peptidase activity
0.60	GO:0046983	protein dimerization activity
0.57	GO:0004175	endopeptidase activity

0.66	GO:0005576	extracellular region
0.55	GO:0005634	nucleus

sp|P61085|UBE2K_BOVIN
Ubiquitin-conjugating enzyme E2 K
Search

UBE2K

0.96	Huntingtin interacting protein 2

0.57	GO:0060340	positive regulation of type I interferon-mediated signaling pathway
0.57	GO:0010994	free ubiquitin chain polymerization
0.57	GO:0035458	cellular response to interferon-beta
0.56	GO:0010800	positive regulation of peptidyl-threonine phosphorylation
0.55	GO:0070936	protein K48-linked ubiquitination
0.54	GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process
0.45	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.39	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
0.34	GO:0009107	lipoate biosynthetic process
0.34	GO:0009249	protein lipoylation

0.55	GO:0034450	ubiquitin-ubiquitin ligase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0031625	ubiquitin protein ligase binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0061631	ubiquitin conjugating enzyme activity
0.34	GO:0016992	lipoate synthase activity
0.33	GO:0051539	4 iron, 4 sulfur cluster binding
0.32	GO:0046872	metal ion binding

0.57	GO:0032433	filopodium tip
0.45	GO:0005634	nucleus
0.39	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.34

EC:2.8.1.8

GO:0016992

sp|P61157|ARP3_BOVIN
Actin-related protein 3
Search

ACTR3

0.85	Actin-related protein 3

0.81	GO:0034314	Arp2/3 complex-mediated actin nucleation
0.55	GO:0016344	meiotic chromosome movement towards spindle pole
0.53	GO:0033206	meiotic cytokinesis
0.52	GO:0071346	cellular response to interferon-gamma
0.52	GO:0008356	asymmetric cell division
0.51	GO:0051653	spindle localization
0.50	GO:0060271	cilium assembly
0.50	GO:0007163	establishment or maintenance of cell polarity
0.36	GO:1905836	response to triterpenoid
0.36	GO:1905834	response to pyrimidine ribonucleotide

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0051015	actin filament binding
0.48	GO:0005200	structural constituent of cytoskeleton
0.35	GO:0051117	ATPase binding

0.80	GO:0005885	Arp2/3 protein complex
0.51	GO:0030027	lamellipodium
0.51	GO:0005903	brush border
0.48	GO:0005911	cell-cell junction
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.36	GO:0061830	concave side of sperm head
0.36	GO:0061828	apical tubulobulbar complex
0.36	GO:0061825	podosome core
0.35	GO:0030056	hemidesmosome

sp|P61223|RAP1B_BOVIN
Ras-related protein Rap-1b
Search

RAP1B

0.94	RAP1B, member of RAS oncogene family

0.61	GO:0032486	Rap protein signal transduction
0.60	GO:0061028	establishment of endothelial barrier
0.60	GO:0071320	cellular response to cAMP
0.59	GO:1901888	regulation of cell junction assembly
0.58	GO:2000301	negative regulation of synaptic vesicle exocytosis
0.54	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.52	GO:2001214	positive regulation of vasculogenesis
0.49	GO:0010976	positive regulation of neuron projection development
0.48	GO:2000114	regulation of establishment of cell polarity
0.44	GO:0008283	cell proliferation

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.53	GO:0032403	protein complex binding
0.51	GO:0019003	GDP binding
0.46	GO:0017016	Ras GTPase binding
0.44	GO:0008565	protein transporter activity
0.37	GO:0005085	guanyl-nucleotide exchange factor activity
0.36	GO:0017056	structural constituent of nuclear pore
0.35	GO:0004708	MAP kinase kinase activity

0.54	GO:0030054	cell junction
0.50	GO:0032045	guanyl-nucleotide exchange factor complex
0.49	GO:0005811	lipid droplet
0.48	GO:0043209	myelin sheath
0.47	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0043005	neuron projection
0.46	GO:0005829	cytosol
0.41	GO:0005886	plasma membrane
0.39	GO:0031982	vesicle
0.39	GO:0043230	extracellular organelle

0.35

GO:0004708

sp|P61257|RL26_BOVIN
60S ribosomal protein L26
Search

RPL26

0.79	Ribosomal protein L26, pseudogene 2

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.55	GO:1902167	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
0.54	GO:1904803	regulation of translation involved in cellular response to UV
0.54	GO:1902164	positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
0.54	GO:0010467	gene expression
0.53	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
0.53	GO:0009059	macromolecule biosynthetic process
0.52	GO:0042273	ribosomal large subunit biogenesis
0.52	GO:0071480	cellular response to gamma radiation

0.64	GO:0003735	structural constituent of ribosome
0.49	GO:0048027	mRNA 5'-UTR binding
0.34	GO:0005515	protein binding
0.33	GO:0046872	metal ion binding

0.71	GO:0015934	large ribosomal subunit
0.53	GO:0022626	cytosolic ribosome
0.46	GO:0005730	nucleolus
0.45	GO:0005654	nucleoplasm
0.37	GO:0070062	extracellular exosome
0.34	GO:0043195	terminal bouton
0.30	GO:0031224	intrinsic component of membrane

sp|P61267|STX1B_BOVIN
Syntaxin-1B
Search

STX1A

0.56	Syntaxin-4

0.70	GO:0017157	regulation of exocytosis
0.69	GO:0016192	vesicle-mediated transport
0.69	GO:0006886	intracellular protein transport
0.68	GO:0061025	membrane fusion
0.61	GO:0001956	positive regulation of neurotransmitter secretion
0.60	GO:2000463	positive regulation of excitatory postsynaptic potential
0.60	GO:1902803	regulation of synaptic vesicle transport
0.59	GO:0098693	regulation of synaptic vesicle cycle
0.56	GO:0097480	establishment of synaptic vesicle localization
0.56	GO:0099504	synaptic vesicle cycle

0.80	GO:0005484	SNAP receptor activity
0.67	GO:0000149	SNARE binding
0.54	GO:0019900	kinase binding
0.50	GO:0019869	chloride channel inhibitor activity
0.50	GO:0019855	calcium channel inhibitor activity
0.47	GO:0005102	receptor binding
0.44	GO:0017022	myosin binding
0.40	GO:0043008	ATP-dependent protein binding
0.40	GO:0019904	protein domain specific binding
0.40	GO:0048306	calcium-dependent protein binding

0.57	GO:0098793	presynapse
0.55	GO:0030424	axon
0.55	GO:0031201	SNARE complex
0.54	GO:0070382	exocytic vesicle
0.47	GO:0030658	transport vesicle membrane
0.46	GO:0031965	nuclear membrane
0.44	GO:0005886	plasma membrane
0.39	GO:0034705	potassium channel complex
0.39	GO:0042641	actomyosin
0.39	GO:0014069	postsynaptic density

sp|P61282|NEDD8_BOVIN
NEDD8
Search

NEDD8

0.75	Neural precursor cell expressed, developmentally down-regulated 8

0.77	GO:0045116	protein neddylation
0.61	GO:0036099	female germ-line stem cell population maintenance
0.60	GO:0030431	sleep
0.59	GO:2000736	regulation of stem cell differentiation
0.59	GO:0006357	regulation of transcription by RNA polymerase II
0.59	GO:0008589	regulation of smoothened signaling pathway
0.57	GO:0051438	regulation of ubiquitin-protein transferase activity
0.56	GO:0008283	cell proliferation
0.55	GO:0031647	regulation of protein stability
0.55	GO:0008104	protein localization

0.65	GO:0031625	ubiquitin protein ligase binding
0.45	GO:0016791	phosphatase activity
0.39	GO:0031386	protein tag
0.37	GO:0004252	serine-type endopeptidase activity
0.36	GO:0004519	endonuclease activity

0.58	GO:0005654	nucleoplasm
0.57	GO:0005829	cytosol
0.42	GO:0070062	extracellular exosome

0.45

EC:3.1.3 EC:3.1.3.41

GO:0016791

sp|P61283|BAF_BOVIN
Barrier-to-autointegration factor
Search

BANF1

0.94	Barrier-to-autointegration factor B

0.52	GO:0045071	negative regulation of viral genome replication
0.36	GO:0075713	establishment of integrated proviral latency
0.35	GO:0015074	DNA integration
0.35	GO:0007077	mitotic nuclear envelope disassembly
0.35	GO:0010951	negative regulation of endopeptidase activity
0.35	GO:0007084	mitotic nuclear envelope reassembly
0.34	GO:0051169	nuclear transport
0.34	GO:0009615	response to virus

0.56	GO:0097726	LEM domain binding
0.55	GO:0003677	DNA binding
0.51	GO:0047485	protein N-terminus binding
0.50	GO:0008022	protein C-terminus binding
0.47	GO:0042803	protein homodimerization activity
0.46	GO:0019899	enzyme binding
0.36	GO:0004869	cysteine-type endopeptidase inhibitor activity

0.45	GO:0005654	nucleoplasm
0.45	GO:0005829	cytosol
0.39	GO:0005635	nuclear envelope
0.38	GO:0005694	chromosome
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

sp|P61284|RL12_BOVIN
60S ribosomal protein L12
Search

RPL12

0.72	Alpha-tubulin N-acetyltransferase 1 (Fragment)

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.50	GO:0000027	ribosomal large subunit assembly
0.34	GO:0045901	positive regulation of translational elongation
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.33	GO:0016072	rRNA metabolic process

0.64	GO:0003735	structural constituent of ribosome
0.45	GO:0019843	rRNA binding
0.34	GO:0005515	protein binding
0.32	GO:0016740	transferase activity

0.61	GO:0005840	ribosome
0.47	GO:0044445	cytosolic part
0.42	GO:0044446	intracellular organelle part
0.36	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.35	GO:0043233	organelle lumen
0.34	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016740

sp|P61285|DYL1_BOVIN
Dynein light chain 1, cytoplasmic
Search

DYNLL1

0.89	Cytoplasmic light-chain dynein

0.72	GO:0007017	microtubule-based process
0.51	GO:0030705	cytoskeleton-dependent intracellular transport
0.51	GO:2000582	positive regulation of ATP-dependent microtubule motor activity, plus-end-directed
0.51	GO:0060271	cilium assembly
0.48	GO:1902857	positive regulation of non-motile cilium assembly
0.46	GO:0006928	movement of cell or subcellular component
0.46	GO:0042326	negative regulation of phosphorylation
0.45	GO:0031503	protein complex localization
0.41	GO:0006886	intracellular protein transport
0.38	GO:0006915	apoptotic process

0.53	GO:0045505	dynein intermediate chain binding
0.50	GO:0051959	dynein light intermediate chain binding
0.50	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed
0.45	GO:0008022	protein C-terminus binding
0.45	GO:0008092	cytoskeletal protein binding
0.44	GO:0019904	protein domain specific binding
0.39	GO:0097110	scaffold protein binding
0.39	GO:0030235	nitric-oxide synthase regulator activity
0.37	GO:0042803	protein homodimerization activity
0.37	GO:0046982	protein heterodimerization activity

0.79	GO:0030286	dynein complex
0.50	GO:0005813	centrosome
0.48	GO:0072686	mitotic spindle
0.48	GO:0008180	COP9 signalosome
0.48	GO:0000776	kinetochore
0.45	GO:0005929	cilium
0.44	GO:0031475	myosin V complex
0.41	GO:0005829	cytosol
0.39	GO:0005874	microtubule
0.38	GO:1904115	axon cytoplasm

0.50

EC:3.6.4.4

GO:0008574

sp|P61286|PABP1_BOVIN
Polyadenylate-binding protein 1
Search

PABPC1

0.60	Polyadenylate-binding protein 1-A

0.45	GO:2000623	negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.44	GO:0045070	positive regulation of viral genome replication
0.39	GO:0007507	heart development
0.37	GO:0060212	negative regulation of nuclear-transcribed mRNA poly(A) tail shortening
0.37	GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
0.36	GO:0048255	mRNA stabilization
0.36	GO:0031047	gene silencing by RNA
0.35	GO:0006417	regulation of translation
0.35	GO:0006397	mRNA processing
0.34	GO:0043043	peptide biosynthetic process

0.59	GO:0003723	RNA binding
0.42	GO:0008022	protein C-terminus binding
0.37	GO:0031370	eukaryotic initiation factor 4G binding
0.36	GO:0043621	protein self-association

0.48	GO:0005737	cytoplasm
0.42	GO:0071013	catalytic step 2 spliceosome
0.41	GO:0035770	ribonucleoprotein granule
0.36	GO:0005844	polysome

sp|P61287|PP1G_BOVIN
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit
Search

PPP1CC

0.49	Serine/threonine-protein phosphatase

0.72	GO:0006470	protein dephosphorylation
0.59	GO:0043153	entrainment of circadian clock by photoperiod
0.57	GO:0032922	circadian regulation of gene expression
0.50	GO:0046822	regulation of nucleocytoplasmic transport
0.48	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
0.46	GO:0048754	branching morphogenesis of an epithelial tube
0.46	GO:0030324	lung development
0.44	GO:0098609	cell-cell adhesion
0.41	GO:0005977	glycogen metabolic process
0.39	GO:0051301	cell division

0.77	GO:0004722	protein serine/threonine phosphatase activity
0.54	GO:0046872	metal ion binding
0.51	GO:0047485	protein N-terminus binding
0.48	GO:0019901	protein kinase binding
0.47	GO:0098641	cadherin binding involved in cell-cell adhesion
0.40	GO:0008157	protein phosphatase 1 binding
0.39	GO:0005521	lamin binding
0.38	GO:0008022	protein C-terminus binding
0.38	GO:0032403	protein complex binding
0.37	GO:0019904	protein domain specific binding

0.84	GO:0000164	protein phosphatase type 1 complex
0.65	GO:0072357	PTW/PP1 phosphatase complex
0.54	GO:0000784	nuclear chromosome, telomeric region
0.48	GO:0005730	nucleolus
0.48	GO:0005741	mitochondrial outer membrane
0.46	GO:0005913	cell-cell adherens junction
0.45	GO:0005654	nucleoplasm
0.42	GO:0097610	cell surface furrow
0.42	GO:0043234	protein complex
0.42	GO:0005829	cytosol

sp|P61356|RL27_BOVIN
60S ribosomal protein L27
Search

RPL27

0.75	60S ribosomal protein L27

0.59	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.44	GO:0030218	erythrocyte differentiation
0.42	GO:0016072	rRNA metabolic process
0.42	GO:0042254	ribosome biogenesis
0.35	GO:1904044	response to aldosterone
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane

0.63	GO:0003735	structural constituent of ribosome
0.34	GO:0003723	RNA binding
0.32	GO:0016787	hydrolase activity

0.61	GO:0005840	ribosome
0.47	GO:0098556	cytoplasmic side of rough endoplasmic reticulum membrane
0.44	GO:0044445	cytosolic part
0.36	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.34	GO:0005634	nucleus

0.32

GO:0016787

sp|P61420|VA0D1_BOVIN
V-type proton ATPase subunit d 1
Search

ATP6V0D1

0.68	V-type proton ATPase subunit

0.76	GO:0015991	ATP hydrolysis coupled proton transport
0.54	GO:0036295	cellular response to increased oxygen levels
0.49	GO:0030003	cellular cation homeostasis
0.48	GO:0055072	iron ion homeostasis
0.47	GO:0035675	neuromast hair cell development
0.47	GO:0045851	pH reduction
0.46	GO:0008057	eye pigment granule organization
0.46	GO:0039022	pronephric duct development
0.46	GO:0003406	retinal pigment epithelium development
0.46	GO:0070986	left/right axis specification

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.51	GO:0036442	proton-exporting ATPase activity
0.49	GO:0015662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
0.42	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
0.36	GO:0032403	protein complex binding

0.79	GO:0033179	proton-transporting V-type ATPase, V0 domain
0.53	GO:0016471	vacuolar proton-transporting V-type ATPase complex
0.52	GO:0005769	early endosome
0.50	GO:0005813	centrosome
0.46	GO:0005765	lysosomal membrane
0.40	GO:0016324	apical plasma membrane
0.38	GO:0043679	axon terminus
0.37	GO:0008021	synaptic vesicle
0.36	GO:0070062	extracellular exosome
0.35	GO:0030670	phagocytic vesicle membrane

sp|P61585|RHOA_BOVIN
Transforming protein RhoA
Search

RHOA

0.87	transforming protein RhoA

0.77	GO:0007264	small GTPase mediated signal transduction
0.76	GO:1902766	skeletal muscle satellite cell migration
0.74	GO:0090505	epiboly involved in wound healing
0.52	GO:0043149	stress fiber assembly
0.52	GO:1904695	positive regulation of vascular smooth muscle contraction
0.51	GO:0001998	angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure
0.51	GO:0043366	beta selection
0.50	GO:0003100	regulation of systemic arterial blood pressure by endothelin
0.50	GO:0090324	negative regulation of oxidative phosphorylation
0.50	GO:0021861	forebrain radial glial cell differentiation

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.44	GO:0017022	myosin binding
0.43	GO:0051022	Rho GDP-dissociation inhibitor binding
0.41	GO:0019003	GDP binding
0.40	GO:0004602	glutathione peroxidase activity
0.40	GO:0019904	protein domain specific binding

0.49	GO:0030027	lamellipodium
0.48	GO:0032587	ruffle membrane
0.47	GO:0097610	cell surface furrow
0.46	GO:0032155	cell division site part
0.46	GO:0043296	apical junction complex
0.45	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.45	GO:0030496	midbody
0.44	GO:0043197	dendritic spine
0.44	GO:0005938	cell cortex
0.44	GO:0005829	cytosol

0.40

EC:1.11.1.9

GO:0004602

sp|P61602|NCALD_BOVIN
Neurocalcin-delta
Search

NCALD

0.92	Kv channel-interacting protein 1

0.54	GO:0003073	regulation of systemic arterial blood pressure
0.53	GO:0019722	calcium-mediated signaling
0.42	GO:0048841	regulation of axon extension involved in axon guidance
0.40	GO:1901385	regulation of voltage-gated calcium channel activity
0.40	GO:0071277	cellular response to calcium ion
0.39	GO:0048839	inner ear development
0.33	GO:0016192	vesicle-mediated transport
0.32	GO:0055085	transmembrane transport

0.70	GO:0005509	calcium ion binding
0.52	GO:0030276	clathrin binding
0.51	GO:0003779	actin binding
0.50	GO:0015631	tubulin binding
0.38	GO:0042802	identical protein binding
0.34	GO:0015276	ligand-gated ion channel activity

0.37	GO:0005622	intracellular
0.36	GO:0070062	extracellular exosome
0.34	GO:0012506	vesicle membrane
0.34	GO:0048475	coated membrane
0.34	GO:0019898	extrinsic component of membrane
0.34	GO:0098805	whole membrane
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0012505	endomembrane system
0.33	GO:0098796	membrane protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|P61603|CH10_BOVIN
10 kDa heat shock protein, mitochondrial
Search

HSPE1

0.85	Heat shock protein, mitochondrial

0.68	GO:0006457	protein folding
0.50	GO:0006986	response to unfolded protein
0.38	GO:0001649	osteoblast differentiation
0.36	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process

0.52	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0051087	chaperone binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0051082	unfolded protein binding
0.39	GO:0046872	metal ion binding
0.35	GO:0003723	RNA binding

0.48	GO:0005737	cytoplasm
0.45	GO:0043233	organelle lumen
0.43	GO:0043231	intracellular membrane-bounded organelle
0.41	GO:0044446	intracellular organelle part
0.38	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

sp|P61625|ITAL_BOVIN
Integrin alpha-L
Search

ITGAL

0.97	Lymphocyte function-associated antigen-1 alpha subunit

0.80	GO:0007229	integrin-mediated signaling pathway
0.72	GO:0007155	cell adhesion
0.61	GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell
0.57	GO:0043113	receptor clustering
0.41	GO:0050798	activated T cell proliferation
0.40	GO:0050850	positive regulation of calcium-mediated signaling
0.40	GO:0006909	phagocytosis
0.40	GO:0042102	positive regulation of T cell proliferation
0.37	GO:0043312	neutrophil degranulation
0.37	GO:0006952	defense response

0.61	GO:0030369	ICAM-3 receptor activity
0.54	GO:0050839	cell adhesion molecule binding
0.39	GO:0032403	protein complex binding
0.39	GO:0046982	protein heterodimerization activity
0.35	GO:0046872	metal ion binding
0.34	GO:0031072	heat shock protein binding

0.81	GO:0008305	integrin complex
0.53	GO:0009986	cell surface
0.40	GO:0001772	immunological synapse
0.40	GO:0098552	side of membrane
0.39	GO:0070062	extracellular exosome
0.38	GO:0005911	cell-cell junction
0.37	GO:0035579	specific granule membrane
0.35	GO:0044853	plasma membrane raft
0.34	GO:0101003	ficolin-1-rich granule membrane
0.34	GO:0070821	tertiary granule membrane

sp|P61635|STAT3_BOVIN
Signal transducer and activator of transcription 3
Search

STAT3

0.70	Signal transducer and activator of transcription

0.61	GO:0007165	signal transduction
0.58	GO:1904685	positive regulation of metalloendopeptidase activity
0.57	GO:0006351	transcription, DNA-templated
0.57	GO:0006355	regulation of transcription, DNA-templated
0.57	GO:0072540	T-helper 17 cell lineage commitment
0.56	GO:0042755	eating behavior
0.56	GO:0060019	radial glial cell differentiation
0.56	GO:1905564	positive regulation of vascular endothelial cell proliferation
0.56	GO:0048592	eye morphogenesis
0.56	GO:2001223	negative regulation of neuron migration

0.64	GO:0004871	signal transducer activity
0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0001103	RNA polymerase II repressing transcription factor binding
0.55	GO:0003677	DNA binding
0.53	GO:0019903	protein phosphatase binding
0.51	GO:0019901	protein kinase binding
0.51	GO:0003682	chromatin binding
0.50	GO:0001067	regulatory region nucleic acid binding
0.49	GO:0042803	protein homodimerization activity
0.39	GO:0031730	CCR5 chemokine receptor binding

0.61	GO:0005634	nucleus
0.49	GO:0005667	transcription factor complex
0.48	GO:0005737	cytoplasm
0.48	GO:0000785	chromatin
0.46	GO:0070013	intracellular organelle lumen
0.41	GO:0005886	plasma membrane
0.35	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

sp|P61763|STXB1_BOVIN
Syntaxin-binding protein 1
Search

STXBP1

0.94	Syntaxin-binding protein 1

0.80	GO:0006904	vesicle docking involved in exocytosis
0.54	GO:0032229	negative regulation of synaptic transmission, GABAergic
0.54	GO:0002576	platelet degranulation
0.53	GO:0099011	neuronal dense core vesicle exocytosis
0.53	GO:0007412	axon target recognition
0.53	GO:0070527	platelet aggregation
0.52	GO:0016188	synaptic vesicle maturation
0.52	GO:0060292	long term synaptic depression
0.52	GO:0045956	positive regulation of calcium ion-dependent exocytosis
0.51	GO:0007274	neuromuscular synaptic transmission

0.53	GO:0017075	syntaxin-1 binding
0.39	GO:0043274	phospholipase binding
0.38	GO:0047485	protein N-terminus binding
0.37	GO:0019901	protein kinase binding
0.37	GO:0019904	protein domain specific binding
0.36	GO:0042802	identical protein binding
0.34	GO:0003723	RNA binding

0.54	GO:0048787	presynaptic active zone membrane
0.53	GO:0031091	platelet alpha granule
0.50	GO:0045335	phagocytic vesicle
0.49	GO:0043209	myelin sheath
0.48	GO:0030424	axon
0.47	GO:0005829	cytosol
0.47	GO:0005654	nucleoplasm
0.42	GO:0005739	mitochondrion
0.38	GO:0043679	axon terminus
0.37	GO:0048471	perinuclear region of cytoplasm

sp|P61823|RNAS1_BOVIN
Ribonuclease pancreatic
Search

RNASE1

0.47	Pancreatic ribonuclease subtype Nb

0.61	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.45	GO:0016070	RNA metabolic process

0.67	GO:0004522	ribonuclease A activity
0.50	GO:0003676	nucleic acid binding
0.33	GO:0005515	protein binding

0.51	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.67

EC:3.1.27.5

GO:0004522

sp|P61955|SUMO2_BOVIN
Small ubiquitin-related modifier 2
Search

SUMO2

0.75	Small ubiquitin-related modifier

0.80	GO:0016925	protein sumoylation
0.43	GO:1903052	positive regulation of proteolysis involved in cellular protein catabolic process
0.42	GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process
0.42	GO:0043392	negative regulation of DNA binding
0.39	GO:0060216	definitive hemopoiesis
0.38	GO:0043009	chordate embryonic development
0.37	GO:1903322	positive regulation of protein modification by small protein conjugation or removal
0.37	GO:0070911	global genome nucleotide-excision repair
0.36	GO:2000058	regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.36	GO:0034504	protein localization to nucleus

0.49	GO:0031386	protein tag
0.44	GO:0001222	transcription corepressor binding
0.43	GO:0019899	enzyme binding
0.38	GO:0019789	SUMO transferase activity
0.35	GO:0046965	retinoid X receptor binding
0.33	GO:0003723	RNA binding

0.60	GO:0005634	nucleus
0.42	GO:0031974	membrane-enclosed lumen
0.39	GO:0044446	intracellular organelle part
0.36	GO:0070062	extracellular exosome
0.34	GO:0005737	cytoplasm
0.33	GO:0005694	chromosome
0.33	GO:0043234	protein complex

sp|P62157|CALM_BOVIN
Calmodulin
Search

0.50	Calmodulin 1 (phosphorylase kinase, delta)

0.41	GO:0051343	positive regulation of cyclic-nucleotide phosphodiesterase activity
0.41	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity
0.40	GO:0005513	detection of calcium ion
0.40	GO:0032516	positive regulation of phosphoprotein phosphatase activity
0.40	GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
0.40	GO:0030819	positive regulation of cAMP biosynthetic process
0.39	GO:0055117	regulation of cardiac muscle contraction
0.39	GO:0002027	regulation of heart rate
0.39	GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity
0.38	GO:0043388	positive regulation of DNA binding

0.70	GO:0005509	calcium ion binding
0.41	GO:0031997	N-terminal myristoylation domain binding
0.40	GO:0031432	titin binding
0.40	GO:0008179	adenylate cyclase binding
0.40	GO:0072542	protein phosphatase activator activity
0.40	GO:0097718	disordered domain specific binding
0.39	GO:0044325	ion channel binding
0.39	GO:0019855	calcium channel inhibitor activity
0.38	GO:0019901	protein kinase binding
0.36	GO:0016301	kinase activity

0.40	GO:0034703	cation channel complex
0.39	GO:0000922	spindle pole
0.39	GO:0005876	spindle microtubule
0.39	GO:0030017	sarcomere
0.38	GO:0005813	centrosome
0.38	GO:0043209	myelin sheath
0.36	GO:0005887	integral component of plasma membrane
0.35	GO:1902494	catalytic complex
0.35	GO:0043234	protein complex
0.33	GO:0005829	cytosol

sp|P62194|PRS8_BOVIN
26S protease regulatory subunit 8
Search

PSMC5

0.81	Testicular tissue protein Li 149

0.81	GO:1901800	positive regulation of proteasomal protein catabolic process
0.70	GO:0030163	protein catabolic process
0.53	GO:0006508	proteolysis
0.51	GO:0043632	modification-dependent macromolecule catabolic process
0.49	GO:0006357	regulation of transcription by RNA polymerase II
0.48	GO:0045892	negative regulation of transcription, DNA-templated
0.47	GO:2000144	positive regulation of DNA-templated transcription, initiation
0.46	GO:0034976	response to endoplasmic reticulum stress
0.45	GO:0010243	response to organonitrogen compound
0.43	GO:0044267	cellular protein metabolic process

0.82	GO:0036402	proteasome-activating ATPase activity
0.59	GO:0031531	thyrotropin-releasing hormone receptor binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0008134	transcription factor binding
0.49	GO:0008233	peptidase activity
0.36	GO:0003729	mRNA binding
0.35	GO:0043021	ribonucleoprotein complex binding

0.56	GO:1905369	endopeptidase complex
0.48	GO:0005737	cytoplasm
0.48	GO:0097708	intracellular vesicle
0.48	GO:0043234	protein complex
0.46	GO:0005634	nucleus
0.43	GO:0070013	intracellular organelle lumen
0.40	GO:0044446	intracellular organelle part
0.39	GO:0016234	inclusion body
0.38	GO:0098794	postsynapse
0.36	GO:0072562	blood microparticle

0.49

GO:0008233

sp|P62248|MYDGF_BOVIN
Myeloid-derived growth factor
Search

MYDGF

0.52	Myeloid-derived growth factor

0.84	GO:0001938	positive regulation of endothelial cell proliferation
0.83	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling
0.82	GO:0051897	positive regulation of protein kinase B signaling
0.82	GO:0045766	positive regulation of angiogenesis
0.77	GO:0043410	positive regulation of MAPK cascade
0.75	GO:0043066	negative regulation of apoptotic process
0.72	GO:0045944	positive regulation of transcription by RNA polymerase II
0.48	GO:0001525	angiogenesis
0.47	GO:0006915	apoptotic process
0.42	GO:0036498	IRE1-mediated unfolded protein response

0.37	GO:0005515	protein binding
0.35	GO:0008234	cysteine-type peptidase activity
0.33	GO:0017171	serine hydrolase activity

0.72	GO:0005615	extracellular space
0.49	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.44	GO:1903561	extracellular vesicle
0.41	GO:0005788	endoplasmic reticulum lumen

0.35

GO:0008234

sp|P62261|1433E_BOVIN
14-3-3 protein epsilon
Search

YWHAE

0.91	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon

0.55	GO:1905912	regulation of calcium ion export across plasma membrane
0.54	GO:1902309	negative regulation of peptidyl-serine dephosphorylation
0.52	GO:0046827	positive regulation of protein export from nucleus
0.52	GO:0060306	regulation of membrane repolarization
0.52	GO:1901020	negative regulation of calcium ion transmembrane transporter activity
0.51	GO:1901016	regulation of potassium ion transmembrane transporter activity
0.50	GO:0034605	cellular response to heat
0.50	GO:0051480	regulation of cytosolic calcium ion concentration
0.50	GO:0021766	hippocampus development
0.49	GO:0000165	MAPK cascade

0.75	GO:0019904	protein domain specific binding
0.53	GO:0050815	phosphoserine residue binding
0.52	GO:0015459	potassium channel regulator activity
0.52	GO:0097110	scaffold protein binding
0.51	GO:0005246	calcium channel regulator activity
0.51	GO:0044325	ion channel binding
0.51	GO:0042826	histone deacetylase binding
0.50	GO:0045296	cadherin binding
0.49	GO:0031625	ubiquitin protein ligase binding
0.47	GO:0046982	protein heterodimerization activity

0.42	GO:0005634	nucleus
0.42	GO:0090724	central region of growth cone
0.41	GO:0042470	melanosome
0.41	GO:0005739	mitochondrion
0.40	GO:0005886	plasma membrane
0.40	GO:0005871	kinesin complex
0.39	GO:0030424	axon
0.37	GO:0005829	cytosol
0.37	GO:0005925	focal adhesion
0.37	GO:0070062	extracellular exosome

sp|P62276|RS29_BOVIN
40S ribosomal protein S29
Search

RPS29

0.85	Ribosomal protein S29

0.57	GO:0043043	peptide biosynthetic process
0.53	GO:0044267	cellular protein metabolic process
0.52	GO:0010467	gene expression
0.51	GO:0009059	macromolecule biosynthetic process
0.46	GO:0060218	hematopoietic stem cell differentiation
0.46	GO:0048821	erythrocyte development
0.45	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator
0.45	GO:0001570	vasculogenesis
0.44	GO:0001525	angiogenesis
0.43	GO:0043009	chordate embryonic development

0.61	GO:0003735	structural constituent of ribosome
0.44	GO:0008270	zinc ion binding
0.39	GO:0003723	RNA binding
0.32	GO:0016787	hydrolase activity

0.59	GO:0005840	ribosome
0.49	GO:0005844	polysome
0.48	GO:0044445	cytosolic part
0.44	GO:0098556	cytoplasmic side of rough endoplasmic reticulum membrane
0.37	GO:0005925	focal adhesion
0.37	GO:0070062	extracellular exosome
0.34	GO:0005654	nucleoplasm

0.32

GO:0016787

sp|P62285|ASPM_BOVIN
Abnormal spindle-like microcephaly-associated protein homolog (Fragment)
Search

ASPM

0.73	Abnormal spindle microtubule assembly

0.80	GO:0007051	spindle organization
0.65	GO:0045769	negative regulation of asymmetric cell division
0.62	GO:0051661	maintenance of centrosome location
0.62	GO:0021873	forebrain neuroblast division
0.61	GO:0002052	positive regulation of neuroblast proliferation
0.60	GO:0097150	neuronal stem cell population maintenance
0.59	GO:0051653	spindle localization
0.59	GO:0021987	cerebral cortex development
0.59	GO:0008584	male gonad development
0.59	GO:0090263	positive regulation of canonical Wnt signaling pathway

0.62	GO:0005516	calmodulin binding
0.41	GO:0019901	protein kinase binding

0.62	GO:0036449	microtubule minus-end
0.62	GO:0005819	spindle
0.58	GO:0030496	midbody
0.51	GO:0005634	nucleus
0.42	GO:0005737	cytoplasm
0.42	GO:0016324	apical plasma membrane
0.41	GO:0005813	centrosome
0.30	GO:0016021	integral component of membrane

sp|P62326|TYB4_BOVIN
Thymosin beta-4
Search

0.97	Thymosin beta 4 X-linked

0.75	GO:0007015	actin filament organization
0.49	GO:1905271	regulation of proton-transporting ATP synthase activity, rotational mechanism
0.48	GO:0042989	sequestering of actin monomers
0.47	GO:0007253	cytoplasmic sequestering of NF-kappaB
0.47	GO:2000483	negative regulation of interleukin-8 secretion
0.47	GO:2001171	positive regulation of ATP biosynthetic process
0.47	GO:1901223	negative regulation of NIK/NF-kappaB signaling
0.47	GO:2001028	positive regulation of endothelial cell chemotaxis
0.46	GO:1903026	negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding
0.46	GO:0043536	positive regulation of blood vessel endothelial cell migration

0.85	GO:0003785	actin monomer binding
0.41	GO:0019899	enzyme binding
0.36	GO:0003727	single-stranded RNA binding
0.35	GO:0004888	transmembrane signaling receptor activity

0.43	GO:0005856	cytoskeleton
0.42	GO:0005829	cytosol
0.41	GO:0005576	extracellular region
0.40	GO:0005634	nucleus
0.35	GO:0031093	platelet alpha granule lumen
0.30	GO:0016020	membrane

sp|P62739|ACTA_BOVIN
Actin, aortic smooth muscle
Search

ACTA2

0.97	Actin aortic smooth muscle

0.82	GO:0090131	mesenchyme migration
0.66	GO:0010628	positive regulation of gene expression
0.43	GO:0072144	glomerular mesangial cell development
0.42	GO:0008015	blood circulation
0.41	GO:0006936	muscle contraction
0.40	GO:0009615	response to virus
0.39	GO:0003015	heart process
0.39	GO:0035296	regulation of tube diameter
0.39	GO:0003018	vascular process in circulatory system
0.39	GO:0061870	positive regulation of hepatic stellate cell migration

0.54	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0019901	protein kinase binding
0.36	GO:0005200	structural constituent of cytoskeleton

0.77	GO:0030175	filopodium
0.75	GO:0030027	lamellipodium
0.73	GO:0044297	cell body
0.46	GO:0005737	cytoplasm
0.42	GO:0005856	cytoskeleton
0.39	GO:0099512	supramolecular fiber
0.39	GO:0070062	extracellular exosome
0.37	GO:0043234	protein complex
0.37	GO:0044422	organelle part
0.33	GO:0071944	cell periphery

sp|P62763|VISL1_BOVIN
Visinin-like protein 1
Search

VSNL1

0.95	Visinin like 1

0.55	GO:0046676	negative regulation of insulin secretion
0.55	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus
0.54	GO:0045921	positive regulation of exocytosis
0.42	GO:0065009	regulation of molecular function
0.40	GO:0007165	signal transduction
0.34	GO:0007417	central nervous system development

0.70	GO:0005509	calcium ion binding
0.48	GO:0005246	calcium channel regulator activity
0.34	GO:0008022	protein C-terminus binding
0.34	GO:0019904	protein domain specific binding

0.47	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|P62803|H4_BOVIN
Histone H4
Search

sp|P62808|H2B1_BOVIN
Histone H2B type 1
Search

0.86	Histone H2B type 1-H

0.52	GO:0006334	nucleosome assembly
0.38	GO:0002227	innate immune response in mucosa
0.38	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.37	GO:0019731	antibacterial humoral response
0.37	GO:0050830	defense response to Gram-positive bacterium
0.35	GO:0016567	protein ubiquitination
0.33	GO:0006352	DNA-templated transcription, initiation

0.74	GO:0046982	protein heterodimerization activity
0.55	GO:0003677	DNA binding
0.39	GO:0097677	STAT family protein binding
0.37	GO:0044389	ubiquitin-like protein ligase binding
0.36	GO:0042802	identical protein binding

0.74	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.44	GO:0005829	cytosol
0.44	GO:0031974	membrane-enclosed lumen
0.37	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.35	GO:0043234	protein complex

sp|P62811|WFD18_BOVIN
WAP four-disulfide core domain protein 18
Search

0.77	WAP four-disulfide core domain protein 2

0.76	GO:0010466	negative regulation of peptidase activity
0.48	GO:0052548	regulation of endopeptidase activity
0.39	GO:0006508	proteolysis
0.39	GO:0006030	chitin metabolic process
0.36	GO:0097155	fasciculation of sensory neuron axon
0.36	GO:0048920	posterior lateral line neuromast primordium migration
0.36	GO:0097154	GABAergic neuron differentiation
0.36	GO:0071542	dopaminergic neuron differentiation
0.36	GO:0021772	olfactory bulb development
0.35	GO:0007411	axon guidance

0.76	GO:0030414	peptidase inhibitor activity
0.48	GO:0061135	endopeptidase regulator activity
0.39	GO:0008233	peptidase activity
0.39	GO:0008061	chitin binding
0.34	GO:0019899	enzyme binding
0.33	GO:0045735	nutrient reservoir activity
0.33	GO:0003729	mRNA binding
0.32	GO:0003677	DNA binding

0.66	GO:0005576	extracellular region
0.35	GO:0009986	cell surface
0.33	GO:0031982	vesicle
0.31	GO:0005622	intracellular
0.30	GO:0016020	membrane

0.39

GO:0008233

sp|P62833|RAP1A_BOVIN
Ras-related protein Rap-1A
Search

RAP1A

0.92	Ras-related protein O-Krev

0.61	GO:0007165	signal transduction
0.59	GO:0061028	establishment of endothelial barrier
0.59	GO:0071320	cellular response to cAMP
0.58	GO:1901888	regulation of cell junction assembly
0.57	GO:2000301	negative regulation of synaptic vesicle exocytosis
0.54	GO:2001214	positive regulation of vasculogenesis
0.53	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.51	GO:0010976	positive regulation of neuron projection development
0.45	GO:2000114	regulation of establishment of cell polarity
0.44	GO:0015031	protein transport

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.52	GO:0032403	protein complex binding
0.48	GO:0019003	GDP binding
0.48	GO:0017016	Ras GTPase binding
0.46	GO:0008565	protein transporter activity
0.38	GO:0005085	guanyl-nucleotide exchange factor activity
0.35	GO:0004708	MAP kinase kinase activity

0.53	GO:0030054	cell junction
0.52	GO:0032045	guanyl-nucleotide exchange factor complex
0.50	GO:0043209	myelin sheath
0.49	GO:0048471	perinuclear region of cytoplasm
0.48	GO:0043005	neuron projection
0.46	GO:0005811	lipid droplet
0.43	GO:0005829	cytosol
0.41	GO:0005886	plasma membrane
0.40	GO:0070062	extracellular exosome
0.39	GO:0005770	late endosome

0.35

GO:0004708

sp|P62865|UBIM_BOVIN
Ubiquitin-like protein FUBI
Search

FAU

0.97	Ubiquitin-like protein FUBI

0.80	GO:0002227	innate immune response in mucosa
0.78	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.77	GO:0019731	antibacterial humoral response
0.75	GO:0050830	defense response to Gram-positive bacterium

0.54	GO:0003723	RNA binding
0.50	GO:0003735	structural constituent of ribosome
0.49	GO:0005515	protein binding

0.71	GO:0022627	cytosolic small ribosomal subunit
0.65	GO:0005615	extracellular space

sp|P62866|RS30_BOVIN
40S ribosomal protein S30
Search

FAU

0.48	40S ribosomal protein S30

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.52	GO:0002227	innate immune response in mucosa
0.51	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.51	GO:0019731	antibacterial humoral response
0.50	GO:0050830	defense response to Gram-positive bacterium
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane

0.64	GO:0003735	structural constituent of ribosome
0.33	GO:0003723	RNA binding

0.61	GO:0005840	ribosome
0.46	GO:0005615	extracellular space
0.45	GO:0044445	cytosolic part
0.40	GO:0044446	intracellular organelle part
0.33	GO:0043233	organelle lumen
0.33	GO:0005634	nucleus

sp|P62871|GBB1_BOVIN
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
Search

GNB1

0.91	Guanine nucleotide-binding protein beta subunit

0.61	GO:0007165	signal transduction
0.52	GO:0060041	retina development in camera-type eye
0.51	GO:0050909	sensory perception of taste
0.50	GO:0008283	cell proliferation
0.41	GO:0010659	cardiac muscle cell apoptotic process
0.40	GO:0070208	protein heterotrimerization
0.39	GO:0071456	cellular response to hypoxia
0.39	GO:0048920	posterior lateral line neuromast primordium migration
0.39	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.37	GO:0071417	cellular response to organonitrogen compound

0.52	GO:0032403	protein complex binding
0.50	GO:0051020	GTPase binding
0.46	GO:0003924	GTPase activity
0.41	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity
0.41	GO:0031702	type 1 angiotensin receptor binding
0.40	GO:0030507	spectrin binding
0.39	GO:0004871	signal transducer activity
0.36	GO:0005246	calcium channel regulator activity

0.55	GO:0043209	myelin sheath
0.52	GO:0001750	photoreceptor outer segment
0.52	GO:1905360	GTPase complex
0.51	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.45	GO:0098797	plasma membrane protein complex
0.41	GO:0060170	ciliary membrane
0.40	GO:0048471	perinuclear region of cytoplasm
0.40	GO:0044297	cell body
0.40	GO:0001917	photoreceptor inner segment
0.39	GO:0005765	lysosomal membrane

0.41

GO:0047391

sp|P62894|CYC_BOVIN
Cytochrome c
Search

CYCS

0.72	Somatic cytochrome c

0.61	GO:0022900	electron transport chain
0.56	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.46	GO:0006119	oxidative phosphorylation
0.46	GO:0009060	aerobic respiration
0.43	GO:0006915	apoptotic process
0.43	GO:0010730	negative regulation of hydrogen peroxide biosynthetic process
0.43	GO:0042743	hydrogen peroxide metabolic process
0.42	GO:0034465	response to carbon monoxide
0.42	GO:1901857	positive regulation of cellular respiration
0.41	GO:0002931	response to ischemia

0.63	GO:0020037	heme binding
0.63	GO:0045155	electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity
0.54	GO:0046872	metal ion binding
0.38	GO:0019899	enzyme binding

0.62	GO:0070469	respiratory chain
0.61	GO:0005739	mitochondrion
0.58	GO:0031970	organelle envelope lumen
0.50	GO:0005829	cytosol
0.46	GO:0005634	nucleus
0.44	GO:0043209	myelin sheath

sp|P62935|PPIA_BOVIN
Peptidyl-prolyl cis-trans isomerase A
Search

PPIA

0.48	Peptidyl-prolyl cis-trans isomerase A

0.72	GO:0000413	protein peptidyl-prolyl isomerization
0.68	GO:0006457	protein folding
0.50	GO:0045069	regulation of viral genome replication
0.41	GO:0034389	lipid particle organization
0.41	GO:1903902	positive regulation of viral life cycle
0.40	GO:0050714	positive regulation of protein secretion
0.36	GO:0030182	neuron differentiation
0.36	GO:0019061	uncoating of virus
0.35	GO:0035722	interleukin-12-mediated signaling pathway
0.35	GO:0043312	neutrophil degranulation

0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.42	GO:0016018	cyclosporin A binding
0.35	GO:0046790	virion binding
0.35	GO:0005515	protein binding
0.34	GO:0003723	RNA binding

0.43	GO:0005829	cytosol
0.43	GO:0005576	extracellular region
0.41	GO:0005634	nucleus
0.37	GO:0043209	myelin sheath
0.36	GO:0005925	focal adhesion
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen
0.34	GO:0030496	midbody
0.30	GO:0016020	membrane

0.72

GO:0003755

sp|P62954|BLCAP_BOVIN
Bladder cancer-associated protein
Search

BLCAP

0.97	Bladder cancer-associated protein (Fragment)

0.55	GO:0030262	apoptotic nuclear changes
0.38	GO:0007049	cell cycle

0.33

GO:0005515

protein binding

0.30

GO:0044425

membrane part

sp|P62958|HINT1_BOVIN
Histidine triad nucleotide-binding protein 1
Search

HINT1

0.54	Histidine triad nucleotide-binding protein 1

0.52	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator
0.51	GO:0009154	purine ribonucleotide catabolic process
0.48	GO:0050850	positive regulation of calcium-mediated signaling
0.41	GO:1903506	regulation of nucleic acid-templated transcription
0.41	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.41	GO:0010468	regulation of gene expression
0.37	GO:0006351	transcription, DNA-templated
0.33	GO:0016310	phosphorylation

0.38	GO:0016787	hydrolase activity
0.36	GO:0005080	protein kinase C binding
0.36	GO:1901265	nucleoside phosphate binding
0.35	GO:0036094	small molecule binding
0.33	GO:0016301	kinase activity

0.51	GO:0000118	histone deacetylase complex
0.44	GO:0005829	cytosol
0.39	GO:0005886	plasma membrane
0.37	GO:0070062	extracellular exosome
0.34	GO:0005856	cytoskeleton
0.30	GO:0031224	intrinsic component of membrane

0.38

GO:0016787

sp|P62964|RABP1_BOVIN
Cellular retinoic acid-binding protein 1
Search

CRABP1

0.93	Cellular retinoic acid binding protein I

0.85	GO:0034653	retinoic acid catabolic process
0.55	GO:0048385	regulation of retinoic acid receptor signaling pathway
0.48	GO:0048672	positive regulation of collateral sprouting
0.47	GO:0035115	embryonic forelimb morphogenesis
0.34	GO:0051260	protein homooligomerization
0.34	GO:0008544	epidermis development
0.34	GO:0007165	signal transduction
0.32	GO:2001141	regulation of RNA biosynthetic process
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.86	GO:0001972	retinoic acid binding
0.45	GO:0019841	retinol binding
0.44	GO:0016918	retinal binding
0.35	GO:0005515	protein binding
0.33	GO:0044877	macromolecular complex binding
0.33	GO:0005198	structural molecule activity

0.49	GO:0005737	cytoplasm
0.43	GO:0005634	nucleus
0.41	GO:0043233	organelle lumen
0.38	GO:0044446	intracellular organelle part
0.37	GO:0070852	cell body fiber
0.36	GO:0030424	axon
0.34	GO:0070062	extracellular exosome
0.34	GO:0045111	intermediate filament cytoskeleton
0.33	GO:0099512	supramolecular fiber
0.33	GO:0012505	endomembrane system

sp|P62992|RS27A_BOVIN
Ubiquitin-40S ribosomal protein S27a
Search

RPS27A

0.66	Epididymis luminal protein 112

0.60	GO:0006518	peptide metabolic process
0.59	GO:0043604	amide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.54	GO:1901566	organonitrogen compound biosynthetic process
0.54	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.36	GO:0006301	postreplication repair
0.35	GO:0035635	entry of bacterium into host cell
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0035666	TRIF-dependent toll-like receptor signaling pathway

0.63	GO:0003735	structural constituent of ribosome
0.36	GO:0046872	metal ion binding
0.33	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.61	GO:0005840	ribosome
0.50	GO:0043209	myelin sheath
0.46	GO:0044445	cytosolic part
0.41	GO:0044446	intracellular organelle part
0.36	GO:0005634	nucleus
0.36	GO:0070013	intracellular organelle lumen
0.36	GO:0070062	extracellular exosome
0.34	GO:0030139	endocytic vesicle
0.34	GO:0012506	vesicle membrane
0.34	GO:0005768	endosome

sp|P62998|RAC1_BOVIN
Ras-related C3 botulinum toxin substrate 1
Search

RAC1

0.81	Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)

0.76	GO:0007264	small GTPase mediated signal transduction
0.52	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading
0.52	GO:0032707	negative regulation of interleukin-23 production
0.51	GO:0048012	hepatocyte growth factor receptor signaling pathway
0.51	GO:0010592	positive regulation of lamellipodium assembly
0.51	GO:0060263	regulation of respiratory burst
0.50	GO:0051894	positive regulation of focal adhesion assembly
0.50	GO:0090023	positive regulation of neutrophil chemotaxis
0.50	GO:0097178	ruffle assembly
0.50	GO:0030032	lamellipodium assembly

0.67	GO:0003924	GTPase activity
0.65	GO:0005525	GTP binding
0.51	GO:0031996	thioesterase binding
0.47	GO:0019901	protein kinase binding
0.44	GO:0051022	Rho GDP-dissociation inhibitor binding
0.40	GO:0048306	calcium-dependent protein binding
0.40	GO:0030742	GTP-dependent protein binding
0.39	GO:0051117	ATPase binding
0.39	GO:0042826	histone deacetylase binding
0.38	GO:0017137	Rab GTPase binding

0.50	GO:0005884	actin filament
0.49	GO:0043197	dendritic spine
0.49	GO:0055038	recycling endosome membrane
0.49	GO:0032587	ruffle membrane
0.48	GO:0030027	lamellipodium
0.47	GO:0005802	trans-Golgi network
0.47	GO:0036464	cytoplasmic ribonucleoprotein granule
0.40	GO:0042470	melanosome
0.40	GO:0097732	9+2 non-motile cilium
0.40	GO:0030426	growth cone

0.34

EC:2.3.1.48

GO:0004402

sp|P63009|AP2B1_BOVIN
AP-2 complex subunit beta
Search

AP2B1

0.63	AP complex subunit beta

0.69	GO:0006886	intracellular protein transport
0.68	GO:0016192	vesicle-mediated transport
0.51	GO:0060976	coronary vasculature development
0.51	GO:0035904	aorta development
0.51	GO:0003281	ventricular septum development
0.50	GO:0051668	localization within membrane
0.49	GO:0043112	receptor metabolic process
0.46	GO:0098657	import into cell
0.40	GO:0048268	clathrin coat assembly
0.40	GO:0045807	positive regulation of endocytosis

0.79	GO:0030276	clathrin binding
0.38	GO:0032403	protein complex binding
0.35	GO:0019901	protein kinase binding
0.35	GO:0098748	endocytic adaptor activity
0.34	GO:0005048	signal sequence binding
0.32	GO:0005215	transporter activity

0.78	GO:0030131	clathrin adaptor complex
0.51	GO:0030128	clathrin coat of endocytic vesicle
0.50	GO:0030132	clathrin coat of coated pit
0.39	GO:0005794	Golgi apparatus
0.37	GO:0031984	organelle subcompartment
0.35	GO:0036020	endolysosome membrane
0.35	GO:0005829	cytosol
0.34	GO:0098793	presynapse

sp|P63026|VAMP2_BOVIN
Vesicle-associated membrane protein 2
Search

VAMP2

0.76	Chain A, Neuronal Synaptic Fusion Complex

0.69	GO:0016192	vesicle-mediated transport
0.57	GO:0061951	establishment of protein localization to plasma membrane
0.54	GO:0090174	organelle membrane fusion
0.54	GO:1903530	regulation of secretion by cell
0.53	GO:1903540	establishment of protein localization to postsynaptic membrane
0.53	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels
0.53	GO:0099637	neurotransmitter receptor transport
0.53	GO:0016050	vesicle organization
0.52	GO:0023056	positive regulation of signaling
0.52	GO:0097120	receptor localization to synapse

0.55	GO:0000149	SNARE binding
0.49	GO:0005516	calmodulin binding
0.49	GO:0005484	SNAP receptor activity
0.47	GO:0005543	phospholipid binding
0.40	GO:0008022	protein C-terminus binding
0.40	GO:0048306	calcium-dependent protein binding
0.39	GO:0044325	ion channel binding
0.39	GO:0017022	myosin binding
0.37	GO:0032403	protein complex binding
0.37	GO:0042802	identical protein binding

0.59	GO:0031201	SNARE complex
0.55	GO:0030141	secretory granule
0.54	GO:0048471	perinuclear region of cytoplasm
0.52	GO:0030672	synaptic vesicle membrane
0.49	GO:0005802	trans-Golgi network
0.48	GO:0000322	storage vacuole
0.48	GO:0030136	clathrin-coated vesicle
0.47	GO:0055037	recycling endosome
0.47	GO:0045335	phagocytic vesicle
0.47	GO:0009986	cell surface

0.34

EC:1.13.11

GO:0016702

sp|P63048|RL40_BOVIN
Ubiquitin-60S ribosomal protein L40
Search

UBA52

0.63	Anopheles stephensi ubiquitin

0.60	GO:0006518	peptide metabolic process
0.59	GO:0043604	amide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:1901566	organonitrogen compound biosynthetic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.38	GO:0017085	response to insecticide
0.36	GO:0007623	circadian rhythm
0.35	GO:0035635	entry of bacterium into host cell
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition

0.64	GO:0003735	structural constituent of ribosome
0.34	GO:0031386	protein tag
0.33	GO:0005515	protein binding

0.61	GO:0005840	ribosome
0.46	GO:0005829	cytosol
0.43	GO:0005783	endoplasmic reticulum
0.43	GO:0005654	nucleoplasm
0.38	GO:0005886	plasma membrane
0.37	GO:0005765	lysosomal membrane
0.36	GO:0043209	myelin sheath
0.36	GO:0070062	extracellular exosome
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0030666	endocytic vesicle membrane

sp|P63097|GNAI1_BOVIN
Guanine nucleotide-binding protein G(i) subunit alpha-1
Search

GNAI1

0.79	Guanine nucleotide binding protein alpha inhibiting 1

0.82	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.57	GO:1904778	positive regulation of protein localization to cell cortex
0.54	GO:0060236	regulation of mitotic spindle organization
0.49	GO:0051301	cell division
0.44	GO:0007212	dopamine receptor signaling pathway
0.44	GO:0016239	positive regulation of macroautophagy
0.44	GO:1904321	response to forskolin
0.43	GO:0043949	regulation of cAMP-mediated signaling
0.43	GO:1901655	cellular response to ketone
0.42	GO:0046039	GTP metabolic process

0.81	GO:0031683	G-protein beta/gamma-subunit complex binding
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.64	GO:0004871	signal transducer activity
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0031821	G-protein coupled serotonin receptor binding
0.38	GO:0032794	GTPase activating protein binding
0.38	GO:0000287	magnesium ion binding

0.57	GO:0030496	midbody
0.54	GO:0005813	centrosome
0.53	GO:0099738	cell cortex region
0.51	GO:0005730	nucleolus
0.47	GO:1905360	GTPase complex
0.46	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.42	GO:0098797	plasma membrane protein complex
0.41	GO:0000139	Golgi membrane
0.41	GO:0005789	endoplasmic reticulum membrane
0.37	GO:0045121	membrane raft

sp|P63099|CANB1_BOVIN
Calcineurin subunit B type 1
Search

PPP3R1

0.93	Calcineurin B regulatory subunit

0.46	GO:0051531	NFAT protein import into nucleus
0.45	GO:0033173	calcineurin-NFAT signaling cascade
0.45	GO:0060487	lung epithelial cell differentiation
0.44	GO:0001569	branching involved in blood vessel morphogenesis
0.44	GO:0022011	myelination in peripheral nervous system
0.44	GO:0001837	epithelial to mesenchymal transition
0.42	GO:0007507	heart development
0.41	GO:0006470	protein dephosphorylation
0.39	GO:0045944	positive regulation of transcription by RNA polymerase II
0.35	GO:1900739	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway

0.70	GO:0005509	calcium ion binding
0.42	GO:0016018	cyclosporin A binding
0.41	GO:0004721	phosphoprotein phosphatase activity
0.39	GO:0019904	protein domain specific binding
0.38	GO:0043130	ubiquitin binding
0.35	GO:0019899	enzyme binding
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.34	GO:0005516	calmodulin binding

0.43	GO:0042383	sarcolemma
0.41	GO:0005955	calcineurin complex
0.36	GO:0005829	cytosol
0.33	GO:0005654	nucleoplasm
0.33	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.41

EC:3.1.3.16

GO:0004721

sp|P63103|1433Z_BOVIN
14-3-3 protein zeta/delta
Search

YWHAZ

0.87	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta

0.52	GO:0090168	Golgi reassembly
0.51	GO:0051683	establishment of Golgi localization
0.48	GO:0006605	protein targeting
0.46	GO:0010941	regulation of cell death
0.46	GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway
0.45	GO:0051220	cytoplasmic sequestering of protein
0.44	GO:0035308	negative regulation of protein dephosphorylation
0.41	GO:0043085	positive regulation of catalytic activity
0.37	GO:0055114	oxidation-reduction process
0.36	GO:0006839	mitochondrial transport

0.77	GO:0019904	protein domain specific binding
0.52	GO:0045296	cadherin binding
0.49	GO:0044325	ion channel binding
0.49	GO:0042802	identical protein binding
0.48	GO:0019899	enzyme binding
0.45	GO:0050815	phosphoserine residue binding
0.45	GO:0008134	transcription factor binding
0.42	GO:0004497	monooxygenase activity
0.36	GO:0032403	protein complex binding
0.36	GO:0008022	protein C-terminus binding

0.44	GO:0048471	perinuclear region of cytoplasm
0.44	GO:0042470	melanosome
0.42	GO:0005634	nucleus
0.41	GO:0005739	mitochondrion
0.41	GO:0005829	cytosol
0.38	GO:0005925	focal adhesion
0.38	GO:0070062	extracellular exosome
0.36	GO:0072562	blood microparticle
0.36	GO:0030659	cytoplasmic vesicle membrane
0.35	GO:0017053	transcriptional repressor complex

sp|P63171|DYLT1_BOVIN
Dynein light chain Tctex-type 1
Search

DYNLT1

0.93	Dynein light chain Tctex-type 1

0.85	GO:0019060	intracellular transport of viral protein in host cell
0.50	GO:0000132	establishment of mitotic spindle orientation
0.49	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.49	GO:0050768	negative regulation of neurogenesis
0.46	GO:0010976	positive regulation of neuron projection development
0.46	GO:0048468	cell development
0.46	GO:1905709	negative regulation of membrane permeability
0.46	GO:0008090	retrograde axonal transport
0.46	GO:0035022	positive regulation of Rac protein signal transduction
0.45	GO:0008340	determination of adult lifespan

0.73	GO:0042802	identical protein binding
0.46	GO:0003774	motor activity
0.45	GO:0051959	dynein light intermediate chain binding
0.45	GO:0097718	disordered domain specific binding
0.45	GO:0045505	dynein intermediate chain binding
0.44	GO:0008022	protein C-terminus binding
0.41	GO:0031681	G-protein beta-subunit binding
0.41	GO:0030742	GTP-dependent protein binding
0.40	GO:0046983	protein dimerization activity
0.35	GO:0042623	ATPase activity, coupled

0.82	GO:0005868	cytoplasmic dynein complex
0.81	GO:0005881	cytoplasmic microtubule
0.77	GO:0099503	secretory vesicle
0.61	GO:0044216	other organism cell
0.61	GO:0018995	host
0.49	GO:0033267	axon part
0.47	GO:0030426	growth cone
0.47	GO:0005819	spindle
0.46	GO:0044297	cell body
0.45	GO:0120111	neuron projection cytoplasm

sp|P63212|GBG2_BOVIN
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
Search

GNG2

0.71	Guanine nucleotide-binding protein subunit gamma

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.47	GO:0030308	negative regulation of cell growth
0.44	GO:0008283	cell proliferation
0.44	GO:0048010	vascular endothelial growth factor receptor signaling pathway
0.44	GO:0002040	sprouting angiogenesis
0.37	GO:0071380	cellular response to prostaglandin E stimulus
0.37	GO:0071417	cellular response to organonitrogen compound
0.36	GO:0071869	response to catecholamine
0.36	GO:0033762	response to glucagon
0.36	GO:0019933	cAMP-mediated signaling

0.64	GO:0004871	signal transducer activity
0.52	GO:0031681	G-protein beta-subunit binding
0.35	GO:0003924	GTPase activity

0.81	GO:1905360	GTPase complex
0.80	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.65	GO:0098797	plasma membrane protein complex
0.39	GO:0005829	cytosol
0.38	GO:0070062	extracellular exosome
0.34	GO:0014069	postsynaptic density
0.34	GO:0030425	dendrite
0.34	GO:0044297	cell body
0.30	GO:0016021	integral component of membrane

sp|P63214|GBG3_BOVIN
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
Search

GNG3

0.71	Guanine nucleotide-binding protein subunit gamma

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.43	GO:0008283	cell proliferation
0.42	GO:0048010	vascular endothelial growth factor receptor signaling pathway
0.42	GO:0002040	sprouting angiogenesis
0.38	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.37	GO:0071377	cellular response to glucagon stimulus
0.36	GO:0071380	cellular response to prostaglandin E stimulus
0.36	GO:0071870	cellular response to catecholamine stimulus
0.36	GO:0019933	cAMP-mediated signaling
0.35	GO:0000187	activation of MAPK activity

0.64	GO:0004871	signal transducer activity
0.50	GO:0031681	G-protein beta-subunit binding
0.40	GO:0031702	type 1 angiotensin receptor binding
0.36	GO:0003924	GTPase activity

0.81	GO:1905360	GTPase complex
0.80	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.66	GO:0098797	plasma membrane protein complex
0.52	GO:0014069	postsynaptic density
0.51	GO:0030425	dendrite
0.51	GO:0044297	cell body
0.38	GO:0005829	cytosol
0.35	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

sp|P63217|GBG5_BOVIN
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
Search

GNG5

0.71	Guanine nucleotide-binding protein subunit gamma

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.51	GO:0072513	positive regulation of secondary heart field cardioblast proliferation
0.49	GO:2000179	positive regulation of neural precursor cell proliferation
0.43	GO:0030308	negative regulation of cell growth
0.37	GO:0071377	cellular response to glucagon stimulus
0.35	GO:0007368	determination of left/right symmetry
0.34	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.32	GO:0005975	carbohydrate metabolic process

0.64	GO:0004871	signal transducer activity
0.51	GO:0030165	PDZ domain binding
0.34	GO:0003924	GTPase activity
0.34	GO:0008061	chitin binding
0.33	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.81	GO:1905360	GTPase complex
0.79	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.65	GO:0098797	plasma membrane protein complex
0.41	GO:0031680	G-protein beta/gamma-subunit complex
0.41	GO:0005739	mitochondrion
0.37	GO:0070062	extracellular exosome
0.34	GO:0036064	ciliary basal body
0.34	GO:0005813	centrosome

0.33

EC:3.2.1

GO:0004553

sp|P63243|RACK1_BOVIN
Receptor of activated protein C kinase 1
Search

0.82	Guanine nucleotide-binding protein beta subunit

0.70	GO:0033123	positive regulation of purine nucleotide catabolic process
0.70	GO:0030807	positive regulation of cyclic nucleotide catabolic process
0.70	GO:1903208	negative regulation of hydrogen peroxide-induced neuron death
0.69	GO:0030820	regulation of cAMP catabolic process
0.69	GO:0051343	positive regulation of cyclic-nucleotide phosphodiesterase activity
0.67	GO:0032464	positive regulation of protein homooligomerization
0.67	GO:0051901	positive regulation of mitochondrial depolarization
0.66	GO:0050765	negative regulation of phagocytosis
0.66	GO:2000543	positive regulation of gastrulation
0.66	GO:0042998	positive regulation of Golgi to plasma membrane protein transport

0.68	GO:0030292	protein tyrosine kinase inhibitor activity
0.66	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process
0.65	GO:0042169	SH2 domain binding
0.65	GO:0005080	protein kinase C binding
0.64	GO:0030971	receptor tyrosine kinase binding
0.62	GO:0035591	signaling adaptor activity
0.62	GO:0019903	protein phosphatase binding
0.61	GO:0030332	cyclin binding
0.60	GO:0045296	cadherin binding
0.57	GO:0043022	ribosome binding

0.68	GO:1990630	IRE1-RACK1-PP2A complex
0.65	GO:0001891	phagocytic cup
0.62	GO:0030496	midbody
0.60	GO:0048471	perinuclear region of cytoplasm
0.57	GO:0005654	nucleoplasm
0.56	GO:0043025	neuronal cell body
0.56	GO:0005829	cytosol
0.54	GO:0030425	dendrite
0.48	GO:0005739	mitochondrion
0.44	GO:0070062	extracellular exosome

sp|P63258|ACTG_BOVIN
Actin, cytoplasmic 2
Search

ACTB

0.63	Actin cytoplasmic 1

0.53	GO:0098974	postsynaptic actin cytoskeleton organization
0.52	GO:0072749	cellular response to cytochalasin B
0.49	GO:0032091	negative regulation of protein binding
0.46	GO:0045214	sarcomere organization
0.46	GO:0071346	cellular response to interferon-gamma
0.44	GO:0048870	cell motility
0.39	GO:0070527	platelet aggregation
0.39	GO:0001895	retina homeostasis
0.37	GO:0021762	substantia nigra development
0.37	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis

0.53	GO:0098973	structural constituent of postsynaptic actin cytoskeleton
0.51	GO:0030554	adenyl nucleotide binding
0.51	GO:0030957	Tat protein binding
0.51	GO:0050998	nitric-oxide synthase binding
0.51	GO:0097367	carbohydrate derivative binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0008144	drug binding
0.50	GO:0042802	identical protein binding
0.49	GO:0019894	kinesin binding
0.49	GO:0005522	profilin binding

0.76	GO:0097433	dense body
0.70	GO:0005925	focal adhesion
0.61	GO:0005856	cytoskeleton
0.53	GO:0043209	myelin sheath
0.50	GO:0005886	plasma membrane
0.47	GO:0035267	NuA4 histone acetyltransferase complex
0.47	GO:0036464	cytoplasmic ribonucleoprotein granule
0.47	GO:0070062	extracellular exosome
0.46	GO:0044448	cell cortex part
0.45	GO:0005829	cytosol

sp|P63292|SLIB_BOVIN
Somatoliberin
Search

GHRH

0.91	somatoliberin precursor

0.76	GO:0010469	regulation of receptor activity
0.67	GO:0030252	growth hormone secretion
0.66	GO:0060124	positive regulation of growth hormone secretion
0.65	GO:0021984	adenohypophysis development
0.65	GO:0032094	response to food
0.63	GO:0040018	positive regulation of multicellular organism growth
0.62	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.59	GO:0008284	positive regulation of cell proliferation
0.51	GO:0046005	positive regulation of circadian sleep/wake cycle, REM sleep
0.50	GO:0030819	positive regulation of cAMP biosynthetic process

0.79	GO:0005179	hormone activity
0.69	GO:0031770	growth hormone-releasing hormone receptor binding

0.66	GO:0005576	extracellular region
0.63	GO:0043195	terminal bouton
0.42	GO:0043204	perikaryon
0.39	GO:0005622	intracellular

sp|P63296|SECR_BOVIN
Secretin
Search

SCT

0.46

Secretin

0.76	GO:0010469	regulation of receptor activity
0.51	GO:1903640	negative regulation of gastrin-induced gastric acid secretion
0.50	GO:0090274	positive regulation of somatostatin secretion
0.50	GO:0090187	positive regulation of pancreatic juice secretion
0.48	GO:0043950	positive regulation of cAMP-mediated signaling
0.48	GO:0007420	brain development
0.47	GO:0097150	neuronal stem cell population maintenance
0.47	GO:0048566	embryonic digestive tract development
0.47	GO:0008542	visual learning
0.46	GO:0043524	negative regulation of neuron apoptotic process

0.79	GO:0005179	hormone activity
0.46	GO:0047485	protein N-terminus binding

0.66

GO:0005576

extracellular region

sp|P63315|TNNC1_BOVIN
Troponin C, slow skeletal and cardiac muscles
Search

TNNC1

0.94	Troponin C, slow skeletal and cardiac muscles

0.61	GO:0006941	striated muscle contraction
0.60	GO:0060047	heart contraction
0.59	GO:0032972	regulation of muscle filament sliding speed
0.58	GO:0003231	cardiac ventricle development
0.57	GO:0014883	transition between fast and slow fiber
0.56	GO:0003229	ventricular cardiac muscle tissue development
0.56	GO:0055008	cardiac muscle tissue morphogenesis
0.55	GO:0003206	cardiac chamber morphogenesis
0.52	GO:0043462	regulation of ATPase activity
0.50	GO:0050881	musculoskeletal movement

0.69	GO:0005509	calcium ion binding
0.59	GO:0031014	troponin T binding
0.59	GO:0031013	troponin I binding
0.58	GO:0048306	calcium-dependent protein binding
0.53	GO:0051015	actin filament binding
0.51	GO:0042803	protein homodimerization activity

0.59	GO:1990584	cardiac Troponin complex
0.35	GO:0097512	cardiac myofibril
0.33	GO:0005829	cytosol

sp|P67774|PP2AA_BOVIN
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
Search

PPP2CA

0.47	Serine/threonine-protein phosphatase

0.72	GO:0006470	protein dephosphorylation
0.52	GO:0010719	negative regulation of epithelial to mesenchymal transition
0.51	GO:0007498	mesoderm development
0.51	GO:0008637	apoptotic mitochondrial changes
0.50	GO:0042542	response to hydrogen peroxide
0.49	GO:0071902	positive regulation of protein serine/threonine kinase activity
0.48	GO:0034976	response to endoplasmic reticulum stress
0.47	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.46	GO:0046677	response to antibiotic
0.42	GO:1904528	positive regulation of microtubule binding

0.72	GO:0004721	phosphoprotein phosphatase activity
0.53	GO:0050811	GABA receptor binding
0.52	GO:0008022	protein C-terminus binding
0.49	GO:0046982	protein heterodimerization activity
0.37	GO:0046872	metal ion binding
0.35	GO:1990405	protein antigen binding
0.35	GO:0031698	beta-2 adrenergic receptor binding
0.35	GO:0048156	tau protein binding
0.35	GO:0043422	protein kinase B binding
0.35	GO:0051721	protein phosphatase 2A binding

0.57	GO:0000159	protein phosphatase type 2A complex
0.50	GO:0000775	chromosome, centromeric region
0.45	GO:0005829	cytosol
0.43	GO:0000922	spindle pole
0.40	GO:0005886	plasma membrane
0.39	GO:0005634	nucleus
0.38	GO:0070062	extracellular exosome
0.35	GO:0043195	terminal bouton
0.34	GO:0014069	postsynaptic density
0.33	GO:0005739	mitochondrion

0.72

EC:3.1.3.16

GO:0004721

sp|P67808|YBOX1_BOVIN
Nuclease-sensitive element-binding protein 1
Search

YBX1

0.92	TSH receptor suppressor element-binding protein-1

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.52	GO:1903608	protein localization to cytoplasmic stress granule
0.51	GO:1902369	negative regulation of RNA catabolic process
0.50	GO:0051154	negative regulation of striated muscle cell differentiation
0.48	GO:1903312	negative regulation of mRNA metabolic process
0.46	GO:0001701	in utero embryonic development
0.46	GO:0006366	transcription by RNA polymerase II
0.45	GO:1902680	positive regulation of RNA biosynthetic process

0.54	GO:0003677	DNA binding
0.48	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.46	GO:0001067	regulatory region nucleic acid binding
0.46	GO:0003682	chromatin binding
0.45	GO:0051020	GTPase binding
0.42	GO:0003723	RNA binding
0.37	GO:0008190	eukaryotic initiation factor 4E binding
0.36	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.35	GO:0002039	p53 binding
0.34	GO:0008134	transcription factor binding

0.54	GO:0071204	histone pre-mRNA 3'end processing complex
0.52	GO:0070937	CRD-mediated mRNA stability complex
0.50	GO:0005689	U12-type spliceosomal complex
0.49	GO:0010494	cytoplasmic stress granule
0.47	GO:0031965	nuclear membrane
0.43	GO:0005829	cytosol
0.38	GO:0005576	extracellular region
0.35	GO:1990124	messenger ribonucleoprotein complex
0.35	GO:0031982	vesicle
0.35	GO:0043025	neuronal cell body

0.36

GO:0003755

sp|P67810|SC11A_BOVIN
Signal peptidase complex catalytic subunit SEC11A
Search

SEC11A

0.72	Signal peptidase complex catalytic subunit SEC11

0.80

GO:0006465

signal peptide processing

0.67

GO:0008236

serine-type peptidase activity

0.82	GO:0005787	signal peptidase complex
0.38	GO:0031090	organelle membrane
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

sp|P67827|KC1A_BOVIN
Casein kinase I isoform alpha
Search

CSNK1A1

0.74	Casein kinase I alpha S

0.63	GO:0006468	protein phosphorylation
0.48	GO:0018209	peptidyl-serine modification
0.48	GO:0045104	intermediate filament cytoskeleton organization
0.47	GO:1904424	regulation of GTP binding
0.45	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.45	GO:0007030	Golgi organization
0.43	GO:0016055	Wnt signaling pathway
0.42	GO:0006909	phagocytosis
0.42	GO:0048856	anatomical structure development
0.41	GO:0048869	cellular developmental process

0.66	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005515	protein binding
0.34	GO:0042277	peptide binding
0.33	GO:0000287	magnesium ion binding

0.47	GO:0045095	keratin filament
0.47	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex
0.46	GO:0016607	nuclear speck
0.46	GO:0030877	beta-catenin destruction complex
0.46	GO:0036064	ciliary basal body
0.44	GO:0005813	centrosome
0.42	GO:0000777	condensed chromosome kinetochore
0.41	GO:0005829	cytosol
0.38	GO:0030529	intracellular ribonucleoprotein complex
0.35	GO:0000139	Golgi membrane

0.66

GO:0004674

sp|P67868|CSK2B_BOVIN
Casein kinase II subunit beta
Search

CSNK2B

0.59	Casein kinase II subunit beta

0.76	GO:0045859	regulation of protein kinase activity
0.54	GO:0033211	adiponectin-activated signaling pathway
0.53	GO:0032927	positive regulation of activin receptor signaling pathway
0.53	GO:0061154	endothelial tube morphogenesis
0.52	GO:0043537	negative regulation of blood vessel endothelial cell migration
0.52	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
0.51	GO:0018107	peptidyl-threonine phosphorylation
0.41	GO:0016055	Wnt signaling pathway
0.38	GO:0097421	liver regeneration
0.38	GO:0033574	response to testosterone

0.79	GO:0019887	protein kinase regulator activity
0.52	GO:0016301	kinase activity
0.48	GO:0003682	chromatin binding
0.48	GO:0019904	protein domain specific binding
0.47	GO:0042802	identical protein binding
0.46	GO:0008134	transcription factor binding
0.46	GO:0005102	receptor binding
0.42	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.41	GO:0140096	catalytic activity, acting on a protein
0.36	GO:0043021	ribonucleoprotein complex binding

0.83	GO:0005956	protein kinase CK2 complex
0.52	GO:0031519	PcG protein complex
0.40	GO:0005886	plasma membrane
0.37	GO:0016363	nuclear matrix
0.37	GO:0005737	cytoplasm
0.36	GO:0005929	cilium
0.36	GO:0000785	chromatin
0.36	GO:0070062	extracellular exosome
0.35	GO:0031983	vesicle lumen
0.34	GO:0097708	intracellular vesicle

0.42

GO:0016773

sp|P67939|P53_BOVIN
Cellular tumor antigen p53
Search

TP53

0.84	Cellular tumor antigen p53

0.78	GO:0006915	apoptotic process
0.74	GO:0051262	protein tetramerization
0.67	GO:0007049	cell cycle
0.62	GO:0090200	positive regulation of release of cytochrome c from mitochondria
0.61	GO:0000733	DNA strand renaturation
0.59	GO:0030308	negative regulation of cell growth
0.58	GO:0007569	cell aging
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:0072717	cellular response to actinomycin D
0.57	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator

0.76	GO:0044212	transcription regulatory region DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.57	GO:0001084	transcription factor activity, TFIID-class binding
0.56	GO:0001094	TFIID-class transcription factor binding
0.55	GO:0002039	p53 binding
0.55	GO:0035035	histone acetyltransferase binding
0.55	GO:0051721	protein phosphatase 2A binding
0.54	GO:0097718	disordered domain specific binding
0.54	GO:1990837	sequence-specific double-stranded DNA binding
0.54	GO:0047485	protein N-terminus binding

0.61	GO:0005634	nucleus
0.52	GO:0070013	intracellular organelle lumen
0.51	GO:0005667	transcription factor complex
0.49	GO:0000785	chromatin
0.49	GO:0000428	DNA-directed RNA polymerase complex
0.49	GO:0005737	cytoplasm
0.45	GO:0012505	endomembrane system
0.42	GO:0005657	replication fork
0.36	GO:0035861	site of double-strand break
0.34	GO:0005886	plasma membrane

sp|P67983|MT1A_BOVIN
Metallothionein-1A
Search

0.74	Metallothionein-II, hippocampal

0.64	GO:0071294	cellular response to zinc ion
0.56	GO:0045926	negative regulation of growth
0.48	GO:0036018	cellular response to erythropoietin
0.46	GO:0071276	cellular response to cadmium ion
0.43	GO:0036015	response to interleukin-3
0.43	GO:0010273	detoxification of copper ion
0.42	GO:0007263	nitric oxide mediated signal transduction
0.42	GO:0006882	cellular zinc ion homeostasis
0.41	GO:0035690	cellular response to drug
0.40	GO:0071247	cellular response to chromate

0.54	GO:0046872	metal ion binding
0.35	GO:0008144	drug binding
0.35	GO:0005515	protein binding

0.55	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0005634	nucleus
0.37	GO:0005764	lysosome
0.37	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|P68002|VDAC2_BOVIN
Voltage-dependent anion-selective channel protein 2
Search

VDAC2

0.95	Voltage-dependent anion-selective channel protein 2

0.68	GO:0098656	anion transmembrane transport
0.53	GO:0007339	binding of sperm to zona pellucida
0.52	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway
0.50	GO:0032272	negative regulation of protein polymerization
0.44	GO:0031101	fin regeneration
0.44	GO:0036444	mitochondrial calcium uptake
0.42	GO:0008016	regulation of heart contraction
0.35	GO:0007270	neuron-neuron synaptic transmission
0.35	GO:0015866	ADP transport
0.35	GO:0001662	behavioral fear response

0.76	GO:0008308	voltage-gated anion channel activity
0.41	GO:0042802	identical protein binding
0.40	GO:0015288	porin activity
0.39	GO:0046983	protein dimerization activity
0.35	GO:1901265	nucleoside phosphate binding
0.35	GO:0036094	small molecule binding
0.34	GO:0044325	ion channel binding
0.34	GO:0019901	protein kinase binding
0.33	GO:0003735	structural constituent of ribosome

0.76	GO:0005741	mitochondrial outer membrane
0.52	GO:0001669	acrosomal vesicle
0.52	GO:0042645	mitochondrial nucleoid
0.51	GO:0043209	myelin sheath
0.43	GO:0019866	organelle inner membrane
0.41	GO:0046930	pore complex
0.38	GO:0070382	exocytic vesicle
0.37	GO:0097458	neuron part
0.37	GO:0045121	membrane raft
0.37	GO:0043230	extracellular organelle

sp|P68102|IF2A_BOVIN
Eukaryotic translation initiation factor 2 subunit 1
Search

EIF2S1

0.88	Eukaryotic translation initiation factor 2 subunit alpha

0.72	GO:0006413	translational initiation
0.61	GO:0032057	negative regulation of translational initiation in response to stress
0.57	GO:0034198	cellular response to amino acid starvation
0.56	GO:0034644	cellular response to UV
0.56	GO:1901216	positive regulation of neuron death
0.54	GO:0034976	response to endoplasmic reticulum stress
0.54	GO:0046777	protein autophosphorylation
0.40	GO:2000676	positive regulation of type B pancreatic cell apoptotic process
0.40	GO:0071287	cellular response to manganese ion
0.40	GO:1905098	negative regulation of guanyl-nucleotide exchange factor activity

0.73	GO:0003743	translation initiation factor activity
0.52	GO:0043022	ribosome binding
0.36	GO:0005515	protein binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.59	GO:0005850	eukaryotic translation initiation factor 2 complex
0.58	GO:0005851	eukaryotic translation initiation factor 2B complex
0.55	GO:0010494	cytoplasmic stress granule
0.48	GO:0043614	multi-eIF complex
0.46	GO:0033290	eukaryotic 48S preinitiation complex
0.45	GO:0005634	nucleus
0.41	GO:0044207	translation initiation ternary complex
0.40	GO:0005840	ribosome
0.40	GO:0097451	glial limiting end-foot
0.36	GO:0070062	extracellular exosome

sp|P68103|EF1A1_BOVIN
Elongation factor 1-alpha 1
Search

EEF1A1

0.45	Translation elongation factor EF-1 subunit alpha

0.68	GO:0006414	translational elongation
0.51	GO:0071364	cellular response to epidermal growth factor stimulus
0.35	GO:1904714	regulation of chaperone-mediated autophagy
0.35	GO:1903427	negative regulation of reactive oxygen species biosynthetic process
0.35	GO:1990090	cellular response to nerve growth factor stimulus
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0010976	positive regulation of neuron projection development
0.34	GO:0035690	cellular response to drug
0.34	GO:0007568	aging
0.34	GO:0010942	positive regulation of cell death

0.69	GO:0003746	translation elongation factor activity
0.66	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0032561	guanyl ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0019901	protein kinase binding
0.46	GO:0005516	calmodulin binding
0.43	GO:0000049	tRNA binding
0.34	GO:0003729	mRNA binding
0.32	GO:0008144	drug binding

0.49	GO:0032587	ruffle membrane
0.48	GO:0005737	cytoplasm
0.47	GO:0043209	myelin sheath
0.46	GO:0005730	nucleolus
0.45	GO:0015629	actin cytoskeleton
0.43	GO:0044430	cytoskeletal part
0.37	GO:0070062	extracellular exosome
0.35	GO:0031983	vesicle lumen
0.34	GO:0098562	cytoplasmic side of membrane
0.34	GO:0097708	intracellular vesicle

sp|P68107|FKB1B_BOVIN
Peptidyl-prolyl cis-trans isomerase FKBP1B
Search

FKBP1B

0.61	Peptidyl-prolyl cis-trans isomerase FKBP1B

0.85	GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
0.85	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity
0.84	GO:0033197	response to vitamin E
0.83	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus
0.82	GO:0014808	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
0.82	GO:0098870	action potential propagation
0.81	GO:0010459	negative regulation of heart rate
0.81	GO:0051280	negative regulation of release of sequestered calcium ion into cytosol
0.81	GO:0048680	positive regulation of axon regeneration
0.81	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling

0.81	GO:0019855	calcium channel inhibitor activity
0.77	GO:0005528	FK506 binding
0.76	GO:0044325	ion channel binding
0.70	GO:0030551	cyclic nucleotide binding
0.70	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.66	GO:0005102	receptor binding
0.54	GO:0005219	ryanodine-sensitive calcium-release channel activity

0.82	GO:0016529	sarcoplasmic reticulum
0.75	GO:0030018	Z disc
0.72	GO:0034704	calcium channel complex
0.69	GO:0098827	endoplasmic reticulum subcompartment
0.65	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.64	GO:0098588	bounding membrane of organelle
0.46	GO:0005829	cytosol

0.70

GO:0003755

sp|P68138|ACTS_BOVIN
Actin, alpha skeletal muscle
Search

0.84	Actin alpha skeletal muscle

0.69	GO:0090131	mesenchyme migration
0.59	GO:0030240	skeletal muscle thin filament assembly
0.57	GO:0010628	positive regulation of gene expression
0.54	GO:0014706	striated muscle tissue development
0.54	GO:0007517	muscle organ development
0.51	GO:0014904	myotube cell development
0.50	GO:0048747	muscle fiber development
0.49	GO:0033275	actin-myosin filament sliding
0.47	GO:0055006	cardiac cell development
0.46	GO:0060047	heart contraction

0.52	GO:0032559	adenyl ribonucleotide binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0017022	myosin binding
0.39	GO:0016887	ATPase activity
0.35	GO:0031013	troponin I binding
0.35	GO:0031432	titin binding
0.35	GO:0048306	calcium-dependent protein binding
0.35	GO:0005523	tropomyosin binding
0.34	GO:0003785	actin monomer binding

0.65	GO:0030175	filopodium
0.64	GO:0030027	lamellipodium
0.62	GO:0044297	cell body
0.56	GO:0042641	actomyosin
0.55	GO:0005884	actin filament
0.54	GO:0030017	sarcomere
0.51	GO:0097517	contractile actin filament bundle
0.50	GO:0036379	myofilament
0.38	GO:0072562	blood microparticle
0.37	GO:0070062	extracellular exosome

0.39

GO:0016887

sp|P68210|ENSA_BOVIN
Alpha-endosulfine
Search

ENSA

0.94	Endosulfine alpha b

0.82	GO:0032515	negative regulation of phosphoprotein phosphatase activity
0.66	GO:0051301	cell division
0.66	GO:0007049	cell cycle
0.53	GO:0050796	regulation of insulin secretion
0.38	GO:0045722	positive regulation of gluconeogenesis
0.38	GO:0009749	response to glucose
0.35	GO:0007584	response to nutrient
0.34	GO:0046326	positive regulation of glucose import
0.34	GO:0046579	positive regulation of Ras protein signal transduction
0.34	GO:0007212	dopamine receptor signaling pathway

0.82	GO:0004864	protein phosphatase inhibitor activity
0.56	GO:0019870	potassium channel inhibitor activity
0.49	GO:0005102	receptor binding
0.47	GO:0051721	protein phosphatase 2A binding
0.34	GO:0019901	protein kinase binding

0.48	GO:0005737	cytoplasm
0.36	GO:0005654	nucleoplasm

sp|P68250|1433B_BOVIN
14-3-3 protein beta/alpha
Search

YWHAB

0.96	14-3-3 protein beta/alpha

0.51	GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway
0.49	GO:0051220	cytoplasmic sequestering of protein
0.48	GO:0035308	negative regulation of protein dephosphorylation
0.45	GO:0006605	protein targeting
0.44	GO:0043085	positive regulation of catalytic activity
0.39	GO:0090168	Golgi reassembly
0.39	GO:0051683	establishment of Golgi localization
0.39	GO:0051291	protein heterooligomerization
0.38	GO:0010941	regulation of cell death
0.37	GO:0045892	negative regulation of transcription, DNA-templated

0.73	GO:0019904	protein domain specific binding
0.50	GO:0050815	phosphoserine residue binding
0.49	GO:0045296	cadherin binding
0.49	GO:0042826	histone deacetylase binding
0.46	GO:0042802	identical protein binding
0.38	GO:0008022	protein C-terminus binding
0.38	GO:0044325	ion channel binding
0.38	GO:0003714	transcription corepressor activity
0.38	GO:0032403	protein complex binding
0.37	GO:0031625	ubiquitin protein ligase binding

0.48	GO:0048471	perinuclear region of cytoplasm
0.44	GO:0042470	melanosome
0.43	GO:0005829	cytosol
0.38	GO:0017053	transcriptional repressor complex
0.38	GO:0005925	focal adhesion
0.38	GO:0070062	extracellular exosome
0.37	GO:0005634	nucleus
0.36	GO:0030659	cytoplasmic vesicle membrane
0.35	GO:0005739	mitochondrion
0.35	GO:0043234	protein complex

sp|P68252|1433G_BOVIN
14-3-3 protein gamma
Search

YWHAG

0.97	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma

0.51	GO:0048167	regulation of synaptic plasticity
0.50	GO:0045664	regulation of neuron differentiation
0.45	GO:0006605	protein targeting
0.40	GO:0007507	heart development
0.40	GO:0007420	brain development
0.38	GO:0032869	cellular response to insulin stimulus
0.37	GO:0055114	oxidation-reduction process
0.35	GO:1900740	positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
0.35	GO:0097711	ciliary basal body-plasma membrane docking
0.35	GO:0065009	regulation of molecular function

0.77	GO:0019904	protein domain specific binding
0.53	GO:0005159	insulin-like growth factor receptor binding
0.52	GO:0005080	protein kinase C binding
0.47	GO:0042802	identical protein binding
0.42	GO:0004497	monooxygenase activity
0.39	GO:0030971	receptor tyrosine kinase binding
0.35	GO:0008426	protein kinase C inhibitor activity
0.35	GO:0003779	actin binding
0.35	GO:0035259	glucocorticoid receptor binding
0.34	GO:0017080	sodium channel regulator activity

0.50	GO:0043209	myelin sheath
0.37	GO:0005622	intracellular
0.37	GO:0031982	vesicle
0.36	GO:0005925	focal adhesion
0.36	GO:0043230	extracellular organelle
0.35	GO:0005615	extracellular space
0.34	GO:0031090	organelle membrane
0.34	GO:1905369	endopeptidase complex
0.33	GO:0043234	protein complex
0.32	GO:0005886	plasma membrane

0.34

EC:3.4.25

GO:0004298

sp|P68265|GLTP_BOVIN
Glycolipid transfer protein
Search

GLTP

0.89	Glycolipid transfer protein a

0.83	GO:0120009	intermembrane lipid transfer
0.36	GO:0046836	glycolipid transport
0.35	GO:0006687	glycosphingolipid metabolic process

0.83	GO:0120013	intermembrane lipid transfer activity
0.58	GO:0051861	glycolipid binding
0.50	GO:0042802	identical protein binding
0.36	GO:0017089	glycolipid transporter activity

0.48	GO:0005737	cytoplasm
0.37	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

sp|P68301|MT2_BOVIN
Metallothionein-2
Search

0.75	Metallothionein-II, hippocampal

0.63	GO:0071294	cellular response to zinc ion
0.55	GO:0045926	negative regulation of growth
0.49	GO:0036018	cellular response to erythropoietin
0.46	GO:0071276	cellular response to cadmium ion
0.44	GO:0036015	response to interleukin-3
0.42	GO:0010273	detoxification of copper ion
0.41	GO:0007263	nitric oxide mediated signal transduction
0.41	GO:0035690	cellular response to drug
0.41	GO:0006882	cellular zinc ion homeostasis
0.40	GO:0071247	cellular response to chromate

0.54	GO:0046872	metal ion binding
0.36	GO:0005515	protein binding
0.35	GO:0008144	drug binding

0.54	GO:0048471	perinuclear region of cytoplasm
0.46	GO:0005634	nucleus
0.37	GO:0005764	lysosome
0.36	GO:0005829	cytosol

sp|P68311|ERTS_BOVIN
Erythrodihydroneopterin triphosphate synthetase
Search

0.96	Erythrodihydroneopterin triphosphate synthetase

0.62

GO:0016874

ligase activity

0.62

GO:0016874

sp|P68399|CSK21_BOVIN
Casein kinase II subunit alpha
Search

CSNK2A1

0.78	Casein kinase II subunit alpha

0.63	GO:0006468	protein phosphorylation
0.44	GO:0030307	positive regulation of cell growth
0.43	GO:0045732	positive regulation of protein catabolic process
0.43	GO:0008284	positive regulation of cell proliferation
0.43	GO:0051336	regulation of hydrolase activity
0.42	GO:0032268	regulation of cellular protein metabolic process
0.42	GO:0030177	positive regulation of Wnt signaling pathway
0.42	GO:0035303	regulation of dephosphorylation
0.41	GO:1905818	regulation of chromosome separation
0.40	GO:0043066	negative regulation of apoptotic process

0.68	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0008013	beta-catenin binding
0.42	GO:0019888	protein phosphatase regulator activity
0.41	GO:0047485	protein N-terminus binding
0.38	GO:0042802	identical protein binding
0.36	GO:0043021	ribonucleoprotein complex binding
0.35	GO:0051879	Hsp90 protein binding

0.42	GO:0031519	PcG protein complex
0.41	GO:0016580	Sin3 complex
0.41	GO:0090545	CHD-type complex
0.40	GO:0090568	nuclear transcriptional repressor complex
0.40	GO:0005956	protein kinase CK2 complex
0.34	GO:0005886	plasma membrane
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0004674

sp|P68401|PA1B2_BOVIN
Platelet-activating factor acetylhydrolase IB subunit beta
Search

PAFAH1B2

0.85	Platelet-activating factor acetylhydrolase IB subunit beta

0.57	GO:0007283	spermatogenesis
0.54	GO:0016239	positive regulation of macroautophagy
0.50	GO:0007420	brain development
0.41	GO:0016042	lipid catabolic process
0.36	GO:0043312	neutrophil degranulation
0.35	GO:0044342	type B pancreatic cell proliferation
0.34	GO:0003323	type B pancreatic cell development
0.34	GO:0033227	dsRNA transport
0.34	GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus
0.34	GO:0009749	response to glucose

0.57	GO:0047179	platelet-activating factor acetyltransferase activity
0.47	GO:0016787	hydrolase activity
0.46	GO:0042802	identical protein binding
0.41	GO:0046982	protein heterodimerization activity
0.35	GO:0035612	AP-2 adaptor complex binding
0.35	GO:0035650	AP-1 adaptor complex binding
0.34	GO:0051032	nucleic acid transmembrane transporter activity
0.34	GO:0003725	double-stranded RNA binding

0.54	GO:0001650	fibrillar center
0.49	GO:0005829	cytosol
0.42	GO:0005886	plasma membrane
0.38	GO:0070062	extracellular exosome
0.36	GO:1904813	ficolin-1-rich granule lumen
0.36	GO:0034774	secretory granule lumen
0.34	GO:0005765	lysosomal membrane
0.30	GO:0031224	intrinsic component of membrane

0.57

EC:2.3.1.149

GO:0047179

sp|P68432|H31_BOVIN
Histone H3.1
Search

0.49	GO:0006334	nucleosome assembly
0.41	GO:0051290	protein heterotetramerization
0.40	GO:0034723	DNA replication-dependent nucleosome organization
0.39	GO:0006352	DNA-templated transcription, initiation
0.39	GO:0060968	regulation of gene silencing
0.37	GO:0000183	chromatin silencing at rDNA
0.36	GO:0038111	interleukin-7-mediated signaling pathway
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation
0.35	GO:0045652	regulation of megakaryocyte differentiation
0.35	GO:0032460	negative regulation of protein oligomerization

0.74	GO:0046982	protein heterodimerization activity
0.55	GO:0003677	DNA binding
0.45	GO:0031491	nucleosome binding
0.38	GO:0045296	cadherin binding

0.75	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.37	GO:0031974	membrane-enclosed lumen
0.35	GO:0043234	protein complex
0.34	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

sp|P68509|1433F_BOVIN
14-3-3 protein eta
Search

YWHAH

0.96	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma

0.56	GO:0006713	glucocorticoid catabolic process
0.54	GO:0050774	negative regulation of dendrite morphogenesis
0.53	GO:0042921	glucocorticoid receptor signaling pathway
0.53	GO:0086010	membrane depolarization during action potential
0.52	GO:2000649	regulation of sodium ion transmembrane transporter activity
0.48	GO:0006886	intracellular protein transport
0.47	GO:0045893	positive regulation of transcription, DNA-templated
0.45	GO:0048167	regulation of synaptic plasticity
0.38	GO:0055114	oxidation-reduction process
0.38	GO:0007420	brain development

0.77	GO:0019904	protein domain specific binding
0.54	GO:0035259	glucocorticoid receptor binding
0.52	GO:0017080	sodium channel regulator activity
0.52	GO:0044325	ion channel binding
0.50	GO:0042802	identical protein binding
0.49	GO:0019899	enzyme binding
0.47	GO:0046982	protein heterodimerization activity
0.47	GO:0003779	actin binding
0.46	GO:0005159	insulin-like growth factor receptor binding
0.43	GO:0004497	monooxygenase activity

0.43	GO:0043209	myelin sheath
0.40	GO:0005886	plasma membrane
0.38	GO:0005737	cytoplasm
0.36	GO:0014704	intercalated disc
0.36	GO:0005615	extracellular space
0.36	GO:0031982	vesicle
0.36	GO:0043230	extracellular organelle
0.34	GO:0019773	proteasome core complex, alpha-subunit complex
0.34	GO:0031090	organelle membrane
0.33	GO:0044446	intracellular organelle part

sp|P68530|COX2_BOVIN
Cytochrome c oxidase subunit 2
Search

COX2

0.44	Cytochrome c oxidase subunit 2

0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0022900	electron transport chain
0.33	GO:0006119	oxidative phosphorylation
0.33	GO:0045333	cellular respiration

0.72	GO:0005507	copper ion binding
0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016675	oxidoreductase activity, acting on a heme group of donors
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity

0.62	GO:0070469	respiratory chain
0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.41	GO:0070069	cytochrome complex
0.39	GO:0098796	membrane protein complex
0.34	GO:0098798	mitochondrial protein complex
0.30	GO:0016021	integral component of membrane

0.65

GO:0016675

sp|P68827|NAGPA_BOVIN
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
Search

NAGPA

0.97	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase

0.68	GO:0033299	secretion of lysosomal enzymes
0.39	GO:0006486	protein glycosylation
0.37	GO:0006622	protein targeting to lysosome
0.37	GO:0007040	lysosome organization
0.35	GO:0016311	dephosphorylation
0.34	GO:0005975	carbohydrate metabolic process
0.34	GO:0048666	neuron development
0.33	GO:0007154	cell communication
0.31	GO:0009057	macromolecule catabolic process

0.44	GO:0003944	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase activity
0.36	GO:0003993	acid phosphatase activity
0.35	GO:0030246	carbohydrate binding
0.34	GO:0005515	protein binding
0.34	GO:0046872	metal ion binding
0.33	GO:0008375	acetylglucosaminyltransferase activity

0.45	GO:0005887	integral component of plasma membrane
0.41	GO:0032580	Golgi cisterna membrane

0.44

EC:3.1.4.45

GO:0003944

sp|P69206|MORN_BOVIN
Morphogenetic neuropeptide
Search

0.10	Morphogenetic neuropeptide

0.30	GO:0009966	regulation of signal transduction
0.30	GO:0051301	cell division
0.30	GO:0007049	cell cycle
0.30	GO:0065009	regulation of molecular function

0.30	GO:0005488	binding
0.30	GO:0098772	molecular function regulator

sp|P69341|PARN_BOVIN
Poly(A)-specific ribonuclease PARN
Search

PARN

0.90	Poly(A)-specific ribonuclease (Deadenylation nuclease)

0.74	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic
0.73	GO:0006402	mRNA catabolic process
0.62	GO:0110008	ncRNA deadenylation
0.60	GO:0090669	telomerase RNA stabilization
0.58	GO:1904872	regulation of telomerase RNA localization to Cajal body
0.58	GO:0051973	positive regulation of telomerase activity
0.57	GO:0032212	positive regulation of telomere maintenance via telomerase
0.35	GO:0022414	reproductive process
0.35	GO:0043488	regulation of mRNA stability
0.35	GO:0032501	multicellular organismal process

0.83	GO:0004535	poly(A)-specific ribonuclease activity
0.58	GO:0003723	RNA binding
0.53	GO:0019901	protein kinase binding
0.53	GO:0046872	metal ion binding

0.60	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.35	GO:0043233	organelle lumen
0.34	GO:0043232	intracellular non-membrane-bounded organelle
0.34	GO:0044446	intracellular organelle part

0.83

EC:3.1.13.4

GO:0004535

sp|P69678|CUTA_BOVIN
Protein CutA
Search

CUTA

0.97	CutA divalent cation tolerance homolog

0.77	GO:0010038	response to metal ion
0.45	GO:0008104	protein localization
0.36	GO:0006480	N-terminal protein amino acid methylation
0.34	GO:0019915	lipid storage
0.34	GO:0006986	response to unfolded protein
0.34	GO:0051260	protein homooligomerization
0.33	GO:0046907	intracellular transport
0.33	GO:0070727	cellular macromolecule localization
0.33	GO:0042886	amide transport
0.33	GO:0071702	organic substance transport

0.47	GO:0019899	enzyme binding
0.43	GO:0005507	copper ion binding
0.34	GO:0004795	threonine synthase activity
0.33	GO:0008168	methyltransferase activity
0.33	GO:0030170	pyridoxal phosphate binding

0.36	GO:0070062	extracellular exosome
0.32	GO:0005622	intracellular
0.30	GO:0016020	membrane

0.34

EC:4.2.3.1

GO:0004795

sp|P79098|AMPN_BOVIN
Aminopeptidase N
Search

ANPEP

0.51	Aminopeptidase Ey

0.60	GO:0006508	proteolysis
0.48	GO:0008217	regulation of blood pressure
0.47	GO:0043171	peptide catabolic process
0.46	GO:0007267	cell-cell signaling
0.43	GO:0001525	angiogenesis
0.41	GO:0007165	signal transduction
0.41	GO:0030154	cell differentiation
0.38	GO:0051806	entry into cell of other organism involved in symbiotic interaction
0.38	GO:0044409	entry into host
0.37	GO:0019058	viral life cycle

0.70	GO:0004177	aminopeptidase activity
0.66	GO:0008237	metallopeptidase activity
0.62	GO:0008270	zinc ion binding
0.47	GO:0042277	peptide binding
0.42	GO:0104005	hijacked molecular function
0.33	GO:0004872	receptor activity

0.55	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.54	GO:0070062	extracellular exosome
0.53	GO:0009897	external side of plasma membrane
0.41	GO:0005765	lysosomal membrane
0.36	GO:0012506	vesicle membrane
0.35	GO:0031983	vesicle lumen
0.35	GO:0030141	secretory granule
0.34	GO:0044433	cytoplasmic vesicle part
0.30	GO:0016021	integral component of membrane

0.70

EC:3.4.11

GO:0004177

sp|P79099|AQP2_BOVIN
Aquaporin-2
Search

AQP2

0.95	Aquaporin-2

0.60	GO:0071288	cellular response to mercury ion
0.58	GO:0071280	cellular response to copper ion
0.58	GO:0015793	glycerol transport
0.58	GO:0072205	metanephric collecting duct development
0.58	GO:0003097	renal water transport
0.57	GO:0042631	cellular response to water deprivation
0.55	GO:0055085	transmembrane transport
0.38	GO:0006811	ion transport
0.37	GO:0030157	pancreatic juice secretion
0.37	GO:0015670	carbon dioxide transport

0.69	GO:0022803	passive transmembrane transporter activity
0.59	GO:0015168	glycerol transmembrane transporter activity
0.57	GO:0005372	water transmembrane transporter activity
0.36	GO:0005515	protein binding

0.57	GO:0016324	apical plasma membrane
0.54	GO:0055037	recycling endosome
0.54	GO:0070062	extracellular exosome
0.45	GO:0016323	basolateral plasma membrane
0.42	GO:0030659	cytoplasmic vesicle membrane
0.41	GO:0005794	Golgi apparatus
0.40	GO:0005887	integral component of plasma membrane
0.36	GO:0045178	basal part of cell
0.36	GO:0005902	microvillus
0.36	GO:0030133	transport vesicle

sp|P79100|TRPC4_BOVIN
Short transient receptor potential channel 4
Search

TRPC4

0.97	Short transient receptor potential channel 4

0.76	GO:0070588	calcium ion transmembrane transport
0.58	GO:0014051	gamma-aminobutyric acid secretion
0.57	GO:0070509	calcium ion import
0.55	GO:0048709	oligodendrocyte differentiation
0.49	GO:0006828	manganese ion transport
0.49	GO:0051480	regulation of cytosolic calcium ion concentration
0.35	GO:0051924	regulation of calcium ion transport

0.79	GO:0005262	calcium channel activity
0.56	GO:0008013	beta-catenin binding
0.56	GO:0070679	inositol 1,4,5 trisphosphate binding
0.55	GO:0045296	cadherin binding

0.56	GO:0016323	basolateral plasma membrane
0.56	GO:0034704	calcium channel complex
0.55	GO:0030863	cortical cytoskeleton
0.54	GO:0005901	caveola
0.53	GO:0005911	cell-cell junction
0.53	GO:0009986	cell surface
0.43	GO:0005887	integral component of plasma membrane
0.43	GO:0043234	protein complex

sp|P79101|CPSF3_BOVIN
Cleavage and polyadenylation specificity factor subunit 3
Search

CPSF3

0.92	Cleavage and polyadenylation specificity factor subunit 3

0.87	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage
0.70	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.40	GO:0006369	termination of RNA polymerase II transcription
0.39	GO:0006379	mRNA cleavage
0.39	GO:0006378	mRNA polyadenylation
0.39	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.38	GO:0051028	mRNA transport
0.38	GO:0000398	mRNA splicing, via spliceosome
0.38	GO:0006405	RNA export from nucleus

0.77	GO:0008409	5'-3' exonuclease activity
0.71	GO:0004521	endoribonuclease activity
0.59	GO:0003723	RNA binding
0.38	GO:0005515	protein binding
0.37	GO:0046872	metal ion binding

0.83	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex
0.40	GO:0030529	intracellular ribonucleoprotein complex

sp|P79102|CP3AS_BOVIN
Cytochrome P450 3A28
Search

0.96	Cytochrome P450, subfamily IIIA (Niphedipine oxidase), polypeptide 4

0.53	GO:0055114	oxidation-reduction process
0.50	GO:0002933	lipid hydroxylation
0.48	GO:0009822	alkaloid catabolic process
0.48	GO:0008202	steroid metabolic process
0.44	GO:0070988	demethylation
0.43	GO:0042445	hormone metabolic process
0.41	GO:0016098	monoterpenoid metabolic process
0.41	GO:0042737	drug catabolic process
0.41	GO:1901615	organic hydroxy compound metabolic process
0.41	GO:0042362	fat-soluble vitamin biosynthetic process

0.78	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.52	GO:0008395	steroid hydroxylase activity
0.42	GO:0030343	vitamin D3 25-hydroxylase activity
0.42	GO:0034875	caffeine oxidase activity
0.42	GO:0070576	vitamin D 24-hydroxylase activity
0.39	GO:0005496	steroid binding
0.38	GO:0019899	enzyme binding
0.37	GO:0019825	oxygen binding

0.43	GO:0005789	endoplasmic reticulum membrane
0.40	GO:0031090	organelle membrane
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.78	EC:1.14.14	GO:0016712
0.35	KEGG:R07203	GO:0033777

sp|P79103|RS4_BOVIN
40S ribosomal protein S4
Search

RPS4X

0.67	Ribosomal protein S4, X-linked X isoform variant (Fragment)

0.60	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.49	GO:0008284	positive regulation of cell proliferation
0.48	GO:0045727	positive regulation of translation
0.46	GO:0007275	multicellular organism development
0.38	GO:0060322	head development
0.38	GO:0045471	response to ethanol
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

0.64	GO:0003735	structural constituent of ribosome
0.63	GO:0019843	rRNA binding
0.33	GO:0005515	protein binding

0.61	GO:0005840	ribosome
0.50	GO:0044445	cytosolic part
0.50	GO:0005844	polysome
0.49	GO:0036464	cytoplasmic ribonucleoprotein granule
0.43	GO:0044446	intracellular organelle part
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.35	GO:0031012	extracellular matrix
0.33	GO:0043233	organelle lumen
0.33	GO:0005634	nucleus

sp|P79105|S10AC_BOVIN
Protein S100-A12
Search

S100A12

0.97	Calcium-binding protein A9

0.65	GO:0006955	immune response
0.64	GO:0006952	defense response
0.61	GO:0050727	regulation of inflammatory response
0.59	GO:1902533	positive regulation of intracellular signal transduction
0.58	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling
0.58	GO:0009620	response to fungus
0.56	GO:0031640	killing of cells of other organism
0.55	GO:0006805	xenobiotic metabolic process
0.50	GO:0070488	neutrophil aggregation
0.49	GO:0030593	neutrophil chemotaxis

0.77	GO:0050786	RAGE receptor binding
0.70	GO:0005509	calcium ion binding
0.66	GO:0035662	Toll-like receptor 4 binding
0.66	GO:0050544	arachidonic acid binding
0.56	GO:0008017	microtubule binding
0.50	GO:0008270	zinc ion binding
0.36	GO:0016209	antioxidant activity
0.35	GO:0005507	copper ion binding
0.34	GO:0008144	drug binding

0.49	GO:0005634	nucleus
0.45	GO:0005576	extracellular region
0.42	GO:0030054	cell junction
0.42	GO:0005737	cytoplasm
0.42	GO:0005856	cytoskeleton
0.41	GO:0070013	intracellular organelle lumen
0.38	GO:0044446	intracellular organelle part
0.38	GO:0005886	plasma membrane
0.37	GO:0031983	vesicle lumen
0.35	GO:0097708	intracellular vesicle

sp|P79106|PAFA2_BOVIN
Platelet-activating factor acetylhydrolase 2, cytoplasmic
Search

PAFAH2

0.89	Platelet-activating factor acetylhydrolase

0.71	GO:0016042	lipid catabolic process
0.46	GO:0034441	plasma lipoprotein particle oxidation
0.45	GO:0046469	platelet activating factor metabolic process
0.45	GO:0034374	low-density lipoprotein particle remodeling
0.44	GO:0090026	positive regulation of monocyte chemotaxis
0.41	GO:0034440	lipid oxidation
0.38	GO:0031110	regulation of microtubule polymerization or depolymerization
0.38	GO:0043066	negative regulation of apoptotic process
0.35	GO:0007596	blood coagulation
0.34	GO:0050729	positive regulation of inflammatory response

0.80	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity
0.45	GO:0047499	calcium-independent phospholipase A2 activity
0.42	GO:0005543	phospholipid binding

0.45	GO:0034362	low-density lipoprotein particle
0.38	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0005829	cytosol
0.33	GO:0031966	mitochondrial membrane

0.80

EC:3.1.1.47

GO:0003847

sp|P79107|FCGR3_BOVIN
Low affinity immunoglobulin gamma Fc region receptor III
Search

0.97	High affinity immunoglobulin epsilon receptor subunit alpha

0.56	GO:0038094	Fc-gamma receptor signaling pathway
0.53	GO:0038095	Fc-epsilon receptor signaling pathway
0.52	GO:0045780	positive regulation of bone resorption
0.52	GO:0042119	neutrophil activation
0.43	GO:0002885	positive regulation of hypersensitivity
0.43	GO:0001788	antibody-dependent cellular cytotoxicity
0.43	GO:0002888	positive regulation of myeloid leukocyte mediated immunity
0.42	GO:0001803	regulation of type III hypersensitivity
0.42	GO:0002891	positive regulation of immunoglobulin mediated immune response
0.42	GO:0002892	regulation of type II hypersensitivity

0.57	GO:0019770	IgG receptor activity
0.55	GO:0019767	IgE receptor activity
0.53	GO:0019864	IgG binding
0.41	GO:0019863	IgE binding
0.38	GO:0031774	leukotriene receptor binding
0.35	GO:0034987	immunoglobulin receptor binding

0.53	GO:0009986	cell surface
0.44	GO:0098552	side of membrane
0.42	GO:0070062	extracellular exosome
0.41	GO:0005886	plasma membrane
0.37	GO:0098805	whole membrane
0.35	GO:0030141	secretory granule
0.35	GO:0031225	anchored component of membrane
0.35	GO:0030659	cytoplasmic vesicle membrane
0.34	GO:0098588	bounding membrane of organelle
0.33	GO:0043235	receptor complex

sp|P79110|TXTP_BOVIN
Tricarboxylate transport protein, mitochondrial
Search

SLC25A1

0.48	Plasma membrane citrate carrier

0.51	GO:0006843	mitochondrial citrate transport
0.49	GO:0055085	transmembrane transport
0.40	GO:0010821	regulation of mitochondrion organization
0.39	GO:0048268	clathrin coat assembly
0.37	GO:0006886	intracellular protein transport
0.37	GO:0016192	vesicle-mediated transport
0.37	GO:0046326	positive regulation of glucose import
0.36	GO:0016482	cytosolic transport
0.35	GO:0016197	endosomal transport
0.35	GO:0000278	mitotic cell cycle

0.49	GO:0015137	citrate transmembrane transporter activity
0.39	GO:0032051	clathrin light chain binding
0.36	GO:0005198	structural molecule activity

0.44	GO:0031090	organelle membrane
0.43	GO:0005740	mitochondrial envelope
0.39	GO:0071439	clathrin complex
0.39	GO:0030140	trans-Golgi network transport vesicle
0.39	GO:0030132	clathrin coat of coated pit
0.38	GO:0044433	cytoplasmic vesicle part
0.37	GO:0044431	Golgi apparatus part
0.37	GO:0097443	sorting endosome
0.36	GO:0070062	extracellular exosome
0.36	GO:0005770	late endosome

sp|P79113|NPY2R_BOVIN
Neuropeptide Y receptor type 2
Search

NPY2R

0.96	Neuropeptide Y receptor type 2

0.79	GO:0007218	neuropeptide signaling pathway
0.58	GO:0003214	cardiac left ventricle morphogenesis
0.56	GO:0003151	outflow tract morphogenesis
0.53	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
0.46	GO:0007631	feeding behavior
0.44	GO:0007268	chemical synaptic transmission
0.40	GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep
0.40	GO:0033603	positive regulation of dopamine secretion
0.39	GO:2000252	negative regulation of feeding behavior
0.39	GO:0051967	negative regulation of synaptic transmission, glutamatergic

0.83	GO:0004983	neuropeptide Y receptor activity
0.46	GO:0042923	neuropeptide binding
0.35	GO:0005246	calcium channel regulator activity
0.33	GO:0005515	protein binding

0.52	GO:0097730	non-motile cilium
0.37	GO:0005886	plasma membrane
0.33	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|P79114|MYO10_BOVIN
Unconventional myosin-X
Search

MYO10

0.84	LOW QUALITY PROTEIN: unconventional myosin-X

0.70	GO:0007018	microtubule-based movement
0.58	GO:0051489	regulation of filopodium assembly
0.52	GO:0022409	positive regulation of cell-cell adhesion
0.52	GO:0007165	signal transduction
0.50	GO:0008360	regulation of cell shape
0.40	GO:0030705	cytoskeleton-dependent intracellular transport
0.35	GO:0006909	phagocytosis
0.35	GO:0002253	activation of immune response
0.35	GO:0002252	immune effector process
0.34	GO:0048870	cell motility

0.72	GO:0003779	actin binding
0.71	GO:0003774	motor activity
0.71	GO:0008017	microtubule binding
0.57	GO:0030507	spectrin binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0030898	actin-dependent ATPase activity
0.41	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.39	GO:0005516	calmodulin binding

0.75	GO:0016459	myosin complex
0.56	GO:0030175	filopodium
0.54	GO:0043025	neuronal cell body
0.52	GO:0043005	neuron projection
0.52	GO:0005730	nucleolus
0.50	GO:0005829	cytosol
0.43	GO:0005886	plasma membrane
0.40	GO:0001726	ruffle
0.40	GO:0030027	lamellipodium
0.39	GO:0005938	cell cortex

sp|P79119|EPYC_BOVIN
Epiphycan
Search

EPYC

0.97	Dermatan sulfate proteoglycan 3

0.73	GO:0007409	axonogenesis
0.43	GO:0007565	female pregnancy
0.43	GO:0016525	negative regulation of angiogenesis
0.39	GO:0022617	extracellular matrix disassembly

0.41	GO:0005539	glycosaminoglycan binding
0.40	GO:0005201	extracellular matrix structural constituent
0.39	GO:0005515	protein binding
0.37	GO:0044877	macromolecular complex binding

0.73	GO:0005578	proteinaceous extracellular matrix
0.68	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

sp|P79121|TIMP3_BOVIN
Metalloproteinase inhibitor 3
Search

TIMP3

0.91	Metalloproteinase inhibitor 3

0.74	GO:0010951	negative regulation of endopeptidase activity
0.55	GO:1903984	positive regulation of TRAIL-activated apoptotic signaling pathway
0.55	GO:0051045	negative regulation of membrane protein ectodomain proteolysis
0.53	GO:1904683	regulation of metalloendopeptidase activity
0.53	GO:1905049	negative regulation of metallopeptidase activity
0.52	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.46	GO:0010033	response to organic substance
0.44	GO:0070887	cellular response to chemical stimulus
0.36	GO:0002576	platelet degranulation
0.36	GO:0033273	response to vitamin

0.84	GO:0008191	metalloendopeptidase inhibitor activity
0.45	GO:0002020	protease binding
0.39	GO:0008270	zinc ion binding

0.65	GO:0005576	extracellular region
0.37	GO:0031089	platelet dense granule lumen
0.35	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|P79122|PININ_BOVIN
Pinin
Search

PNN

0.95	Pinin, desmosome associated protein (Fragment)

0.53	GO:0014033	neural crest cell differentiation
0.52	GO:0007155	cell adhesion
0.47	GO:0008380	RNA splicing
0.45	GO:0006397	mRNA processing
0.41	GO:0006351	transcription, DNA-templated
0.40	GO:1903506	regulation of nucleic acid-templated transcription
0.40	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.40	GO:0010468	regulation of gene expression

0.42	GO:0003677	DNA binding
0.37	GO:0003723	RNA binding
0.36	GO:0005515	protein binding
0.36	GO:0005198	structural molecule activity

0.79	GO:0035145	exon-exon junction complex
0.75	GO:0071013	catalytic step 2 spliceosome
0.73	GO:0016607	nuclear speck
0.57	GO:0005911	cell-cell junction
0.49	GO:0070161	anchoring junction
0.39	GO:0005882	intermediate filament
0.35	GO:0005737	cytoplasm
0.35	GO:0005886	plasma membrane
0.33	GO:0030424	axon

sp|P79124|SPL2A_BOVIN
Short palate, lung and nasal epithelium carcinoma-associated protein 2A
Search

BPIFA2

0.93	Short palate, lung and nasal epithelium carcinoma-associated protein 2A

0.39	GO:0019730	antimicrobial humoral response
0.37	GO:0042742	defense response to bacterium

0.72	GO:0008289	lipid binding
0.41	GO:0097367	carbohydrate derivative binding
0.35	GO:0005515	protein binding

0.50	GO:0005576	extracellular region
0.37	GO:0031982	vesicle

sp|P79125|SPL2B_BOVIN
Short palate, lung and nasal epithelium carcinoma-associated protein 2B
Search

BPIFA2

0.92	Short palate, lung and nasal epithelium carcinoma-associated protein 2B

0.38	GO:0019730	antimicrobial humoral response
0.37	GO:0042742	defense response to bacterium

0.72	GO:0008289	lipid binding
0.41	GO:0097367	carbohydrate derivative binding
0.35	GO:0005515	protein binding

0.50	GO:0005576	extracellular region
0.36	GO:0031982	vesicle

sp|P79126|PPM1G_BOVIN
Protein phosphatase 1G
Search

PPM1G

0.77	Protein phosphatase 1G (Formerly 2C), magnesium-dependent, gamma isoform

0.70	GO:0006470	protein dephosphorylation
0.58	GO:0007050	cell cycle arrest
0.44	GO:0007417	central nervous system development

0.75	GO:0004722	protein serine/threonine phosphatase activity
0.51	GO:0046872	metal ion binding
0.36	GO:0005515	protein binding

0.50	GO:0005654	nucleoplasm
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P79132|CAV1_BOVIN
Caveolin-1
Search

CAV1

0.82

Caveolin

0.85	GO:0070836	caveola assembly
0.66	GO:0031295	T cell costimulation
0.64	GO:0031623	receptor internalization
0.63	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.62	GO:1900085	negative regulation of peptidyl-tyrosine autophosphorylation
0.62	GO:1903609	negative regulation of inward rectifier potassium channel activity
0.61	GO:0033484	nitric oxide homeostasis
0.61	GO:0086098	angiotensin-activated signaling pathway involved in heart process
0.61	GO:0060355	positive regulation of cell adhesion molecule production
0.61	GO:0048550	negative regulation of pinocytosis

0.62	GO:0070320	inward rectifier potassium channel inhibitor activity
0.60	GO:0050998	nitric-oxide synthase binding
0.58	GO:0044325	ion channel binding
0.57	GO:0048365	Rac GTPase binding
0.57	GO:0051117	ATPase binding
0.56	GO:0016504	peptidase activator activity
0.55	GO:0032947	protein complex scaffold activity
0.54	GO:0030674	protein binding, bridging
0.54	GO:0019901	protein kinase binding
0.51	GO:0042802	identical protein binding

0.84	GO:0005901	caveola
0.74	GO:0000139	Golgi membrane
0.58	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex
0.58	GO:0002080	acrosomal membrane
0.57	GO:0005768	endosome
0.55	GO:0005925	focal adhesion
0.54	GO:0048471	perinuclear region of cytoplasm
0.52	GO:0005929	cilium
0.52	GO:0005938	cell cortex
0.48	GO:0005887	integral component of plasma membrane

sp|P79134|ANXA6_BOVIN
Annexin A6
Search

ANXA6

0.38

Annexin

0.57	GO:0051560	mitochondrial calcium ion homeostasis
0.54	GO:0006937	regulation of muscle contraction
0.54	GO:0097190	apoptotic signaling pathway
0.52	GO:0051260	protein homooligomerization
0.52	GO:0006816	calcium ion transport
0.47	GO:0003418	growth plate cartilage chondrocyte differentiation
0.45	GO:0031214	biomineral tissue development
0.45	GO:0051283	negative regulation of sequestering of calcium ion
0.44	GO:0034220	ion transmembrane transport
0.39	GO:0001778	plasma membrane repair

0.81	GO:0005544	calcium-dependent phospholipid binding
0.70	GO:0005509	calcium ion binding
0.56	GO:0048306	calcium-dependent protein binding
0.55	GO:0015485	cholesterol binding
0.51	GO:0015276	ligand-gated ion channel activity
0.51	GO:0042803	protein homodimerization activity
0.47	GO:0035374	chondroitin sulfate binding
0.47	GO:0032550	purine ribonucleoside binding
0.47	GO:0019001	guanyl nucleotide binding
0.46	GO:0001786	phosphatidylserine binding

0.55	GO:0031902	late endosome membrane
0.54	GO:0005765	lysosomal membrane
0.53	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0042584	chromaffin granule membrane
0.46	GO:0042470	melanosome
0.46	GO:0030061	mitochondrial crista
0.45	GO:0097517	contractile actin filament bundle
0.45	GO:0042641	actomyosin
0.44	GO:0005925	focal adhesion
0.41	GO:0005829	cytosol

sp|P79135|MX1_BOVIN
Interferon-induced GTP-binding protein Mx1
Search

MX1

0.82	Myxovirus resistance protein 1

0.41	GO:0035455	response to interferon-alpha
0.41	GO:0051607	defense response to virus
0.40	GO:0003374	dynamin family protein polymerization involved in mitochondrial fission
0.40	GO:0046822	regulation of nucleocytoplasmic transport
0.39	GO:0000266	mitochondrial fission
0.38	GO:0051726	regulation of cell cycle
0.38	GO:0045087	innate immune response
0.37	GO:0061025	membrane fusion

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0008017	microtubule binding

0.39	GO:0005643	nuclear pore
0.36	GO:0031966	mitochondrial membrane

sp|P79136|CAPZB_BOVIN
F-actin-capping protein subunit beta
Search

CAPZB

0.72	Capping actin protein of muscle Z-line beta subunit

0.84	GO:0051016	barbed-end actin filament capping
0.73	GO:0030036	actin cytoskeleton organization
0.62	GO:0031115	negative regulation of microtubule polymerization
0.61	GO:0090036	regulation of protein kinase C signaling
0.61	GO:0030032	lamellipodium assembly
0.59	GO:0048747	muscle fiber development
0.56	GO:0031175	neuron projection development
0.50	GO:0051490	negative regulation of filopodium assembly
0.48	GO:0010591	regulation of lamellipodium assembly
0.44	GO:0000902	cell morphogenesis

0.74	GO:0003779	actin binding
0.59	GO:0048487	beta-tubulin binding
0.55	GO:0032403	protein complex binding

0.84	GO:0008290	F-actin capping protein complex
0.60	GO:0014704	intercalated disc
0.59	GO:0001669	acrosomal vesicle
0.59	GO:0005903	brush border
0.59	GO:0030018	Z disc
0.58	GO:0030027	lamellipodium
0.57	GO:0030863	cortical cytoskeleton
0.46	GO:0005884	actin filament
0.30	GO:0016020	membrane

sp|P79244|RL37_BOVIN
60S ribosomal protein L37
Search

RPL37

0.73	Ribosomal protein L37

0.59	GO:0043043	peptide biosynthetic process
0.54	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.33	GO:0016072	rRNA metabolic process
0.33	GO:0042254	ribosome biogenesis

0.63	GO:0019843	rRNA binding
0.62	GO:0003735	structural constituent of ribosome
0.52	GO:0046872	metal ion binding
0.34	GO:0019838	growth factor binding

0.60	GO:0005840	ribosome
0.44	GO:0044445	cytosolic part
0.39	GO:0044446	intracellular organelle part
0.35	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|P79251|VATG1_BOVIN
V-type proton ATPase subunit G 1
Search

ATP6V1G1

0.68	V-type proton ATPase subunit G

0.62	GO:0015992	proton transport
0.55	GO:0055085	transmembrane transport
0.54	GO:0036295	cellular response to increased oxygen levels
0.49	GO:0006879	cellular iron ion homeostasis
0.37	GO:0090383	phagosome acidification
0.36	GO:0033572	transferrin transport
0.36	GO:0008286	insulin receptor signaling pathway
0.36	GO:0016241	regulation of macroautophagy
0.32	GO:0055114	oxidation-reduction process

0.66	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.53	GO:0051117	ATPase binding
0.47	GO:0022853	active ion transmembrane transporter activity
0.44	GO:0015078	hydrogen ion transmembrane transporter activity
0.34	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
0.33	GO:0020037	heme binding
0.33	GO:0005506	iron ion binding

0.83	GO:0016471	vacuolar proton-transporting V-type ATPase complex
0.49	GO:0005765	lysosomal membrane
0.45	GO:0005829	cytosol
0.44	GO:0030285	integral component of synaptic vesicle membrane
0.41	GO:0005886	plasma membrane
0.37	GO:0042470	melanosome
0.36	GO:0070062	extracellular exosome

0.34

EC:1.14.14

GO:0016712

sp|P79255|IL8_BOVIN
Interleukin-8
Search

CXCL8

0.45	Multifunctional fusion protein (Fragment)

0.85	GO:0042119	neutrophil activation
0.85	GO:0030593	neutrophil chemotaxis
0.79	GO:0006954	inflammatory response
0.75	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.60	GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate
0.59	GO:0050930	induction of positive chemotaxis
0.58	GO:2000535	regulation of entry of bacterium into host cell
0.56	GO:0048566	embryonic digestive tract development
0.56	GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway

0.86	GO:0005153	interleukin-8 receptor binding
0.84	GO:0008009	chemokine activity
0.34	GO:0008083	growth factor activity

0.73	GO:0005615	extracellular space
0.37	GO:0005622	intracellular

sp|P79266|GASR_BOVIN
Gastrin/cholecystokinin type B receptor
Search

CCKBR

0.96	Cholecystokinin B receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.56	GO:0001696	gastric acid secretion
0.55	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.54	GO:0008284	positive regulation of cell proliferation
0.53	GO:0048565	digestive tract development
0.52	GO:0048732	gland development
0.37	GO:0007610	behavior
0.37	GO:0090274	positive regulation of somatostatin secretion
0.36	GO:0001821	histamine secretion
0.36	GO:0044849	estrous cycle

0.85	GO:0015054	gastrin receptor activity
0.60	GO:0031741	type B gastrin/cholecystokinin receptor binding
0.54	GO:0004951	cholecystokinin receptor activity
0.36	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity
0.35	GO:0004435	phosphatidylinositol phospholipase C activity
0.33	GO:0005216	ion channel activity

0.37	GO:0005886	plasma membrane
0.33	GO:0005634	nucleus
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.35	EC:3.1.4.11	GO:0004435
0.35	KEGG:R03435	GO:0004435

sp|P79331|ATS2_BOVIN
A disintegrin and metalloproteinase with thrombospondin motifs 2
Search

ADAMTS2

0.93	A disintegrin and metalloproteinase with thrombospondin motifs 2

0.67	GO:0007229	integrin-mediated signaling pathway
0.60	GO:0006508	proteolysis
0.55	GO:0030199	collagen fibril organization
0.54	GO:0030324	lung development
0.53	GO:0043588	skin development
0.52	GO:0007283	spermatogenesis
0.49	GO:0051604	protein maturation
0.42	GO:0032963	collagen metabolic process
0.41	GO:0044243	multicellular organismal catabolic process
0.36	GO:0009056	catabolic process

0.69	GO:0004222	metalloendopeptidase activity
0.57	GO:0008270	zinc ion binding

0.67	GO:0005578	proteinaceous extracellular matrix
0.49	GO:0005615	extracellular space
0.34	GO:1903561	extracellular vesicle

0.69

GO:0004222

sp|P79334|PYGM_BOVIN
Glycogen phosphorylase, muscle form
Search

PYGM

0.68	Glycogen phosphorylase, muscle form

0.74	GO:0005977	glycogen metabolic process
0.68	GO:0009251	glucan catabolic process
0.68	GO:0044247	cellular polysaccharide catabolic process
0.46	GO:0051591	response to cAMP
0.46	GO:0043312	neutrophil degranulation
0.45	GO:0001666	response to hypoxia
0.44	GO:0006874	cellular calcium ion homeostasis

0.80	GO:0008184	glycogen phosphorylase activity
0.79	GO:0102250	linear malto-oligosaccharide phosphorylase activity
0.79	GO:0102499	SHG alpha-glucan phosphorylase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.48	GO:0005515	protein binding
0.46	GO:1901265	nucleoside phosphate binding
0.46	GO:0030246	carbohydrate binding
0.37	GO:0097367	carbohydrate derivative binding
0.37	GO:0043169	cation binding

0.58	GO:0070062	extracellular exosome
0.50	GO:0030016	myofibril
0.49	GO:0030424	axon
0.47	GO:0035578	azurophil granule lumen
0.46	GO:0016529	sarcoplasmic reticulum
0.44	GO:0044449	contractile fiber part
0.41	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|P79342|S10AD_BOVIN
Protein S100-A13
Search

S100A13

0.97	S100 calcium binding protein A13

0.70	GO:0050703	interleukin-1 alpha secretion
0.63	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.51	GO:0090026	positive regulation of monocyte chemotaxis
0.51	GO:0071624	positive regulation of granulocyte chemotaxis
0.50	GO:0034142	toll-like receptor 4 signaling pathway
0.48	GO:0032496	response to lipopolysaccharide
0.47	GO:0042742	defense response to bacterium
0.40	GO:0002279	mast cell activation involved in immune response
0.40	GO:0002448	mast cell mediated immunity
0.40	GO:0051602	response to electrical stimulus

0.70	GO:0005509	calcium ion binding
0.67	GO:0005507	copper ion binding
0.67	GO:0050786	RAGE receptor binding
0.65	GO:0017134	fibroblast growth factor binding
0.58	GO:0042803	protein homodimerization activity
0.50	GO:0008270	zinc ion binding
0.49	GO:0042379	chemokine receptor binding
0.38	GO:0008289	lipid binding
0.33	GO:0008144	drug binding

0.64	GO:0048471	perinuclear region of cytoplasm
0.57	GO:0005829	cytosol
0.57	GO:0031981	nuclear lumen
0.57	GO:0005615	extracellular space
0.48	GO:0005886	plasma membrane
0.48	GO:0043232	intracellular non-membrane-bounded organelle
0.46	GO:0030054	cell junction
0.40	GO:0042629	mast cell granule
0.39	GO:1903561	extracellular vesicle

sp|P79345|NPC2_BOVIN
Epididymal secretory protein E1
Search

NPC2

0.94	NPC intracellular cholesterol transporter 2

0.85	GO:0032367	intracellular cholesterol transport
0.57	GO:0033344	cholesterol efflux
0.54	GO:0042632	cholesterol homeostasis
0.50	GO:0009615	response to virus
0.42	GO:0008203	cholesterol metabolic process
0.35	GO:0046836	glycolipid transport
0.35	GO:0034383	low-density lipoprotein particle clearance
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0019747	regulation of isoprenoid metabolic process
0.34	GO:0015914	phospholipid transport

0.55	GO:0015485	cholesterol binding
0.55	GO:0017127	cholesterol transporter activity
0.48	GO:0019899	enzyme binding
0.33	GO:0035091	phosphatidylinositol binding
0.33	GO:0003887	DNA-directed DNA polymerase activity
0.32	GO:0003677	DNA binding
0.32	GO:1901265	nucleoside phosphate binding

0.52	GO:0005764	lysosome
0.49	GO:0005615	extracellular space
0.39	GO:0005783	endoplasmic reticulum
0.37	GO:1903561	extracellular vesicle
0.35	GO:0034774	secretory granule lumen
0.35	GO:0005775	vacuolar lumen

0.33

GO:0003887

sp|P79348|RGS20_BOVIN
Regulator of G-protein signaling 20
Search

RGS20

0.84	LOW QUALITY PROTEIN: regulator of G-protein signaling 20

0.64	GO:0043547	positive regulation of GTPase activity
0.48	GO:0009968	negative regulation of signal transduction
0.43	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.37	GO:0007186	G-protein coupled receptor signaling pathway

0.64	GO:0005096	GTPase activator activity
0.41	GO:0001965	G-protein alpha-subunit binding

0.74	GO:0005802	trans-Golgi network
0.62	GO:0031410	cytoplasmic vesicle
0.49	GO:0005886	plasma membrane
0.42	GO:0005634	nucleus
0.40	GO:0005903	brush border
0.39	GO:0045121	membrane raft
0.36	GO:0000139	Golgi membrane
0.30	GO:0016021	integral component of membrane

sp|P79350|OPRM_BOVIN
Mu-type opioid receptor
Search

OPRM1

0.97	Mu opioid receptor variant

0.85	GO:0038003	opioid receptor signaling pathway
0.79	GO:0007218	neuropeptide signaling pathway
0.60	GO:0061358	negative regulation of Wnt protein secretion
0.57	GO:0019233	sensory perception of pain
0.55	GO:0071315	cellular response to morphine
0.54	GO:0007187	G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
0.53	GO:0048149	behavioral response to ethanol
0.53	GO:0050769	positive regulation of neurogenesis
0.52	GO:0007212	dopamine receptor signaling pathway
0.51	GO:0019933	cAMP-mediated signaling

0.86	GO:0004979	beta-endorphin receptor activity
0.58	GO:0001965	G-protein alpha-subunit binding
0.56	GO:0038047	morphine receptor activity
0.49	GO:0031681	G-protein beta-subunit binding
0.49	GO:0042923	neuropeptide binding
0.47	GO:0038046	enkephalin receptor activity
0.43	GO:0005245	voltage-gated calcium channel activity
0.39	GO:0031005	filamin binding
0.38	GO:0008022	protein C-terminus binding
0.37	GO:0019904	protein domain specific binding

0.46	GO:0043005	neuron projection
0.44	GO:0043204	perikaryon
0.42	GO:0120038	plasma membrane bounded cell projection part
0.42	GO:0005768	endosome
0.42	GO:0005887	integral component of plasma membrane
0.38	GO:0042383	sarcolemma
0.38	GO:0031256	leading edge membrane
0.38	GO:0005925	focal adhesion
0.38	GO:0098857	membrane microdomain
0.37	GO:0098794	postsynapse

sp|P79391|OLR1_BOVIN
Oxidized low-density lipoprotein receptor 1
Search

OLR1

0.97	Oxidized low-density lipoprotein receptor

0.46	GO:0006954	inflammatory response
0.44	GO:0007155	cell adhesion
0.44	GO:0002376	immune system process
0.41	GO:0008015	blood circulation
0.40	GO:0016192	vesicle-mediated transport
0.39	GO:0032930	positive regulation of superoxide anion generation
0.38	GO:0098657	import into cell
0.38	GO:0035296	regulation of tube diameter
0.38	GO:0003018	vascular process in circulatory system
0.37	GO:0001775	cell activation

0.68	GO:0030246	carbohydrate binding
0.57	GO:0042802	identical protein binding
0.43	GO:0005041	low-density lipoprotein receptor activity

0.60	GO:0043235	receptor complex
0.56	GO:0005654	nucleoplasm
0.48	GO:0005886	plasma membrane
0.46	GO:0045121	membrane raft
0.42	GO:0005576	extracellular region
0.39	GO:0035579	specific granule membrane
0.39	GO:0070821	tertiary granule membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P79393|PI2R_BOVIN
Prostacyclin receptor
Search

PTGIR

0.97	Prostacyclin receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.60	GO:0019933	cAMP-mediated signaling
0.60	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway
0.59	GO:0032496	response to lipopolysaccharide
0.58	GO:0048662	negative regulation of smooth muscle cell proliferation
0.50	GO:0071379	cellular response to prostaglandin stimulus
0.50	GO:0034695	response to prostaglandin E
0.48	GO:1901655	cellular response to ketone
0.48	GO:0097306	cellular response to alcohol
0.46	GO:0032570	response to progesterone

0.72	GO:0004954	prostanoid receptor activity
0.35	GO:0005085	guanyl-nucleotide exchange factor activity

0.49	GO:0005829	cytosol
0.44	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P80012|VWF_BOVIN
von Willebrand factor (Fragment)
Search

VWF

0.39	von Willebrand factor (Fragment)

0.64	GO:0030168	platelet activation
0.62	GO:0031589	cell-substrate adhesion
0.60	GO:0051260	protein homooligomerization
0.38	GO:0007597	blood coagulation, intrinsic pathway
0.38	GO:0002576	platelet degranulation
0.37	GO:0001890	placenta development
0.37	GO:0001889	liver development
0.37	GO:0030198	extracellular matrix organization
0.35	GO:0007399	nervous system development
0.35	GO:0030154	cell differentiation

0.66	GO:0019865	immunoglobulin binding
0.65	GO:0047485	protein N-terminus binding
0.65	GO:0005178	integrin binding
0.64	GO:0002020	protease binding
0.63	GO:0005518	collagen binding
0.60	GO:0051087	chaperone binding
0.58	GO:0042803	protein homodimerization activity
0.36	GO:0005044	scavenger receptor activity

0.69	GO:0033093	Weibel-Palade body
0.66	GO:0005576	extracellular region
0.55	GO:0005783	endoplasmic reticulum
0.39	GO:0031093	platelet alpha granule lumen
0.37	GO:0009897	external side of plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P80025|PERL_BOVIN
Lactoperoxidase
Search

LPO

0.46	lactoperoxidase precursor

0.77	GO:0018969	thiocyanate metabolic process
0.72	GO:0006952	defense response
0.71	GO:0006979	response to oxidative stress
0.69	GO:0098869	cellular oxidant detoxification
0.66	GO:0009617	response to bacterium
0.57	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste
0.54	GO:0002148	hypochlorous acid metabolic process
0.53	GO:0055114	oxidation-reduction process
0.50	GO:1903409	reactive oxygen species biosynthetic process
0.48	GO:0034374	low-density lipoprotein particle remodeling

0.78	GO:0036393	thiocyanate peroxidase activity
0.63	GO:0020037	heme binding
0.45	GO:0008201	heparin binding
0.37	GO:0046872	metal ion binding
0.34	GO:0003682	chromatin binding
0.33	GO:0004984	olfactory receptor activity

0.55	GO:0005615	extracellular space
0.54	GO:0016323	basolateral plasma membrane
0.47	GO:0005766	primary lysosome
0.45	GO:0030141	secretory granule
0.39	GO:1903561	extracellular vesicle
0.39	GO:0005634	nucleus
0.39	GO:0005739	mitochondrion
0.36	GO:0060205	cytoplasmic vesicle lumen
0.34	GO:0005775	vacuolar lumen
0.30	GO:0016021	integral component of membrane

sp|P80109|PHLD_BOVIN
Phosphatidylinositol-glycan-specific phospholipase D
Search

GPLD1

0.97	Glycosylphosphatidylinositol-specific phospholipase D

0.70	GO:0071401	cellular response to triglyceride
0.70	GO:0006507	GPI anchor release
0.68	GO:0045919	positive regulation of cytolysis
0.68	GO:0071397	cellular response to cholesterol
0.67	GO:0002042	cell migration involved in sprouting angiogenesis
0.67	GO:0002430	complement receptor mediated signaling pathway
0.67	GO:0051044	positive regulation of membrane protein ectodomain proteolysis
0.65	GO:0071277	cellular response to calcium ion
0.64	GO:0008286	insulin receptor signaling pathway
0.64	GO:1900076	regulation of cellular response to insulin stimulus

0.87	GO:0004621	glycosylphosphatidylinositol phospholipase D activity
0.48	GO:0017080	sodium channel regulator activity
0.34	GO:0005515	protein binding

0.66	GO:0005576	extracellular region
0.46	GO:0043231	intracellular membrane-bounded organelle
0.42	GO:0005737	cytoplasm
0.41	GO:1990777	lipoprotein particle
0.37	GO:0031982	vesicle
0.37	GO:0098805	whole membrane
0.37	GO:0098588	bounding membrane of organelle
0.35	GO:0044446	intracellular organelle part

0.87

EC:3.1.4.50

GO:0004621

sp|P80177|MIF_BOVIN
Macrophage migration inhibitory factor
Search

MIF

0.85	Macrophage migration inhibitory factor

0.78	GO:0010760	negative regulation of macrophage chemotaxis
0.77	GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
0.77	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator
0.77	GO:0010739	positive regulation of protein kinase A signaling
0.75	GO:0090344	negative regulation of cell aging
0.75	GO:0070207	protein homotrimerization
0.75	GO:0048146	positive regulation of fibroblast proliferation
0.75	GO:0071157	negative regulation of cell cycle arrest
0.75	GO:0046457	prostanoid biosynthetic process
0.75	GO:0030890	positive regulation of B cell proliferation

0.85	GO:0050178	phenylpyruvate tautomerase activity
0.84	GO:0004167	dopachrome isomerase activity
0.76	GO:0042056	chemoattractant activity
0.74	GO:0005125	cytokine activity
0.68	GO:0005126	cytokine receptor binding
0.66	GO:0002020	protease binding
0.64	GO:0042802	identical protein binding
0.49	GO:0042289	MHC class II protein binding
0.37	GO:0032403	protein complex binding
0.33	GO:0003676	nucleic acid binding

0.67	GO:0005615	extracellular space
0.65	GO:0009986	cell surface
0.65	GO:0043209	myelin sheath
0.61	GO:0005654	nucleoplasm
0.60	GO:0005829	cytosol
0.41	GO:1903561	extracellular vesicle
0.40	GO:1904813	ficolin-1-rich granule lumen
0.39	GO:0034774	secretory granule lumen

0.85	EC:5.3.2.1	GO:0050178
0.84	KEGG:R03673	GO:0004167

sp|P80189|LYSCN_BOVIN
Lysozyme C, non-stomach isozyme
Search

LYZ

0.52	Lysozyme C, non-stomach isozyme

0.78	GO:0042742	defense response to bacterium
0.77	GO:0019835	cytolysis
0.47	GO:0031640	killing of cells of other organism
0.46	GO:0016998	cell wall macromolecule catabolic process
0.43	GO:0007586	digestion
0.36	GO:0001895	retina homeostasis
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0019730	antimicrobial humoral response
0.34	GO:0006954	inflammatory response
0.32	GO:0044267	cellular protein metabolic process

0.78	GO:0003796	lysozyme activity
0.45	GO:0042802	identical protein binding

0.49	GO:0005576	extracellular region
0.36	GO:0030141	secretory granule
0.35	GO:0048237	rough endoplasmic reticulum lumen
0.35	GO:0005766	primary lysosome
0.35	GO:0060205	cytoplasmic vesicle lumen
0.35	GO:0005775	vacuolar lumen
0.34	GO:0000137	Golgi cis cisterna
0.34	GO:0005902	microvillus
0.34	GO:0030140	trans-Golgi network transport vesicle

0.78

EC:3.2.1.17

GO:0003796

sp|P80195|GLCM1_BOVIN
Glycosylation-dependent cell adhesion molecule 1
Search

GLYCAM1

0.97	Glycosylation-dependent cell adhesion molecule 1

0.44

GO:0007155

cell adhesion

0.56	GO:0042802	identical protein binding
0.51	GO:0043199	sulfate binding
0.46	GO:0050839	cell adhesion molecule binding

0.51	GO:0005576	extracellular region
0.39	GO:0005886	plasma membrane

sp|P80209|CATD_BOVIN
Cathepsin D
Search

CTSD

0.85	Cathepsin D preproprotein (Predicted)

0.60	GO:0006508	proteolysis
0.46	GO:0003406	retinal pigment epithelium development
0.43	GO:0061061	muscle structure development
0.43	GO:0009617	response to bacterium
0.42	GO:0006914	autophagy
0.40	GO:0030163	protein catabolic process
0.38	GO:0060441	epithelial tube branching involved in lung morphogenesis
0.37	GO:0007033	vacuole organization
0.36	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.36	GO:0043312	neutrophil degranulation

0.69	GO:0070001	aspartic-type peptidase activity
0.64	GO:0004175	endopeptidase activity
0.35	GO:0042277	peptide binding
0.34	GO:0008234	cysteine-type peptidase activity
0.34	GO:0017171	serine hydrolase activity
0.33	GO:0005515	protein binding

0.74	GO:0005764	lysosome
0.44	GO:0042470	melanosome
0.41	GO:0005615	extracellular space
0.38	GO:0045121	membrane raft
0.37	GO:0031012	extracellular matrix
0.37	GO:1903561	extracellular vesicle
0.36	GO:1904724	tertiary granule lumen
0.36	GO:0035580	specific granule lumen
0.36	GO:1904813	ficolin-1-rich granule lumen
0.36	GO:0005775	vacuolar lumen

0.34

GO:0008234

sp|P80219|DDN1_BOVIN
Duodenase-1
Search

GZMB

0.89	Endogenous granzyme B

0.67	GO:0008626	granzyme-mediated apoptotic signaling pathway
0.65	GO:0001909	leukocyte mediated cytotoxicity
0.63	GO:0002228	natural killer cell mediated immunity
0.61	GO:0006508	proteolysis
0.46	GO:0051873	killing by host of symbiont cells
0.45	GO:0002446	neutrophil mediated immunity
0.44	GO:0019731	antibacterial humoral response
0.44	GO:0050830	defense response to Gram-positive bacterium
0.44	GO:0044130	negative regulation of growth of symbiont in host
0.43	GO:0050832	defense response to fungus

0.69	GO:0004252	serine-type endopeptidase activity
0.43	GO:0008201	heparin binding
0.35	GO:0005515	protein binding

0.65	GO:0030141	secretory granule
0.42	GO:0010494	cytoplasmic stress granule
0.41	GO:0031012	extracellular matrix
0.41	GO:0005615	extracellular space
0.38	GO:0044194	cytolytic granule
0.37	GO:0005886	plasma membrane
0.35	GO:0005766	primary lysosome
0.35	GO:0060205	cytoplasmic vesicle lumen
0.35	GO:0005775	vacuolar lumen
0.34	GO:0005829	cytosol

0.69

GO:0004252

sp|P80221|CXCL6_BOVIN
C-X-C motif chemokine 6
Search

0.87	Alveolar macrophage chemotactic factor

0.82	GO:0060326	cell chemotaxis
0.74	GO:0006955	immune response
0.72	GO:0006952	defense response
0.72	GO:0010469	regulation of receptor activity
0.54	GO:0090023	positive regulation of neutrophil chemotaxis
0.54	GO:0002237	response to molecule of bacterial origin
0.52	GO:0070098	chemokine-mediated signaling pathway
0.51	GO:0033993	response to lipid
0.50	GO:0050900	leukocyte migration
0.49	GO:0042127	regulation of cell proliferation

0.84	GO:0008009	chemokine activity
0.57	GO:0045236	CXCR chemokine receptor binding
0.39	GO:0008201	heparin binding
0.38	GO:0042802	identical protein binding
0.37	GO:0008083	growth factor activity
0.34	GO:0004488	methylenetetrahydrofolate dehydrogenase (NADP+) activity
0.33	GO:0005355	glucose transmembrane transporter activity
0.33	GO:0008047	enzyme activator activity
0.32	GO:0016787	hydrolase activity

0.70	GO:0005615	extracellular space
0.36	GO:1904724	tertiary granule lumen
0.35	GO:0034774	secretory granule lumen
0.34	GO:0042581	specific granule
0.34	GO:0031091	platelet alpha granule
0.30	GO:0016020	membrane

0.34	EC:1.5.1.5	GO:0004488
0.34	KEGG:R01220	GO:0004488

sp|P80227|ACPH_BOVIN
Acylamino-acid-releasing enzyme
Search

APEH

0.81	N-acylaminoacyl-peptide hydrolase

0.60	GO:0006508	proteolysis
0.58	GO:0050435	amyloid-beta metabolic process
0.38	GO:0007416	synapse assembly
0.36	GO:0043312	neutrophil degranulation
0.34	GO:0006415	translational termination

0.66	GO:0017171	serine hydrolase activity
0.61	GO:0070011	peptidase activity, acting on L-amino acid peptides
0.51	GO:0042802	identical protein binding
0.34	GO:0003723	RNA binding
0.33	GO:0046872	metal ion binding

0.54	GO:0031965	nuclear membrane
0.49	GO:0005829	cytosol
0.38	GO:0048786	presynaptic active zone
0.37	GO:0070062	extracellular exosome
0.36	GO:1904813	ficolin-1-rich granule lumen

sp|P80311|PPIB_BOVIN
Peptidyl-prolyl cis-trans isomerase B
Search

PPIB

0.49	Peptidyl-prolyl cis-trans isomerase B

0.72	GO:0000413	protein peptidyl-prolyl isomerization
0.68	GO:0006457	protein folding
0.57	GO:0044829	positive regulation by host of viral genome replication
0.55	GO:0040018	positive regulation of multicellular organism growth
0.53	GO:0060348	bone development
0.52	GO:0050821	protein stabilization
0.37	GO:1901873	regulation of post-translational protein modification
0.34	GO:0051169	nuclear transport

0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.51	GO:0070063	RNA polymerase binding
0.49	GO:0032403	protein complex binding
0.34	GO:0051082	unfolded protein binding
0.34	GO:0003723	RNA binding
0.32	GO:0046872	metal ion binding

0.56	GO:0034663	endoplasmic reticulum chaperone complex
0.51	GO:0048471	perinuclear region of cytoplasm
0.44	GO:0005634	nucleus
0.40	GO:0042470	melanosome
0.40	GO:0005788	endoplasmic reticulum lumen
0.40	GO:0005790	smooth endoplasmic reticulum
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.72

GO:0003755

sp|P80343|MCPB_BOVIN
Monocyte chemotactic protein 1B (Fragment)
Search

0.76	C-C motif chemokine

0.82	GO:0060326	cell chemotaxis
0.74	GO:0006955	immune response
0.73	GO:0010469	regulation of receptor activity
0.65	GO:0097529	myeloid leukocyte migration
0.63	GO:2000501	regulation of natural killer cell chemotaxis
0.63	GO:0071674	mononuclear cell migration
0.61	GO:0071347	cellular response to interleukin-1
0.60	GO:0071356	cellular response to tumor necrosis factor
0.59	GO:0006954	inflammatory response
0.58	GO:1901624	negative regulation of lymphocyte chemotaxis

0.84	GO:0008009	chemokine activity
0.61	GO:0048020	CCR chemokine receptor binding
0.51	GO:0016004	phospholipase activator activity
0.43	GO:0008201	heparin binding
0.42	GO:0004672	protein kinase activity
0.37	GO:0046983	protein dimerization activity

0.71	GO:0005615	extracellular space
0.37	GO:0005622	intracellular

sp|P80416|CYTA_BOVIN
Cystatin-A
Search

CSTA

0.86	Leukocyte cysteine proteinase inhibitor 1

0.76	GO:0010951	negative regulation of endopeptidase activity
0.63	GO:0030216	keratinocyte differentiation
0.62	GO:0018149	peptide cross-linking
0.58	GO:0098609	cell-cell adhesion
0.36	GO:0012501	programmed cell death
0.34	GO:0043043	peptide biosynthetic process
0.33	GO:0010467	gene expression
0.33	GO:0009059	macromolecule biosynthetic process

0.83	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.63	GO:0002020	protease binding
0.61	GO:0030674	protein binding, bridging
0.50	GO:0005198	structural molecule activity

0.65	GO:0001533	cornified envelope
0.57	GO:0005615	extracellular space
0.53	GO:0005829	cytosol
0.49	GO:0005634	nucleus
0.40	GO:0031012	extracellular matrix
0.39	GO:1903561	extracellular vesicle
0.34	GO:0005840	ribosome

sp|P80425|FABPL_BOVIN
Fatty acid-binding protein, liver
Search

FABP1

0.83	Fatty acid-binding protein, liver

0.60	GO:0070301	cellular response to hydrogen peroxide
0.59	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.59	GO:0071456	cellular response to hypoxia
0.51	GO:0098869	cellular oxidant detoxification
0.44	GO:0032000	positive regulation of fatty acid beta-oxidation
0.43	GO:0050892	intestinal absorption
0.42	GO:0015909	long-chain fatty acid transport
0.40	GO:0051345	positive regulation of hydrolase activity
0.36	GO:0019433	triglyceride catabolic process
0.36	GO:0051977	lysophospholipid transport

0.76	GO:0005504	fatty acid binding
0.68	GO:0032052	bile acid binding
0.55	GO:0003682	chromatin binding
0.51	GO:0016209	antioxidant activity
0.43	GO:0005324	long-chain fatty acid transporter activity
0.40	GO:0005543	phospholipid binding
0.36	GO:0051978	lysophospholipid transporter activity
0.36	GO:0008144	drug binding
0.35	GO:0005515	protein binding

0.52	GO:0005654	nucleoplasm
0.51	GO:0005829	cytosol
0.43	GO:0045179	apical cortex
0.43	GO:0031907	microbody lumen
0.41	GO:0044439	peroxisomal part
0.38	GO:0070062	extracellular exosome
0.37	GO:0043234	protein complex

sp|P80457|XDH_BOVIN
Xanthine dehydrogenase/oxidase
Search

XDH

0.51	Molybdopterin-binding domain of aldehyde dehydrogenase

0.65	GO:0009115	xanthine catabolic process
0.62	GO:2001213	negative regulation of vasculogenesis
0.60	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway
0.60	GO:0045602	negative regulation of endothelial cell differentiation
0.59	GO:1900745	positive regulation of p38MAPK cascade
0.58	GO:0022900	electron transport chain
0.58	GO:0001937	negative regulation of endothelial cell proliferation
0.58	GO:0051898	negative regulation of protein kinase B signaling
0.57	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.57	GO:2000379	positive regulation of reactive oxygen species metabolic process

0.80	GO:0016727	oxidoreductase activity, acting on CH or CH2 groups, oxygen as acceptor
0.79	GO:0004854	xanthine dehydrogenase activity
0.73	GO:0043546	molybdopterin cofactor binding
0.69	GO:0051537	2 iron, 2 sulfur cluster binding
0.65	GO:0050660	flavin adenine dinucleotide binding
0.64	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors
0.62	GO:0005506	iron ion binding
0.59	GO:0009055	electron transfer activity
0.52	GO:0042803	protein homodimerization activity
0.50	GO:0030151	molybdenum ion binding

0.55	GO:0016529	sarcoplasmic reticulum
0.45	GO:0005829	cytosol
0.43	GO:0005615	extracellular space
0.40	GO:0005777	peroxisome
0.37	GO:0002197	xanthine dehydrogenase complex
0.30	GO:0031224	intrinsic component of membrane

0.80

EC:1.17.3

GO:0016727

sp|P80473|MYOM1_BOVIN
Myomesin-1 (Fragments)
Search

0.10	Myomesin-1 (Fragments)

0.52	GO:0002074	extraocular skeletal muscle development
0.52	GO:0006936	muscle contraction
0.50	GO:0071688	striated muscle myosin thick filament assembly
0.49	GO:0045214	sarcomere organization
0.45	GO:0007015	actin filament organization

0.71	GO:0042803	protein homodimerization activity
0.51	GO:0097493	structural molecule activity conferring elasticity
0.51	GO:0051371	muscle alpha-actinin binding
0.50	GO:0019900	kinase binding
0.50	GO:0008307	structural constituent of muscle
0.46	GO:0051015	actin filament binding
0.46	GO:0005200	structural constituent of cytoskeleton

0.85	GO:0031430	M band
0.50	GO:0005859	muscle myosin complex
0.48	GO:0030018	Z disc
0.38	GO:0005739	mitochondrion

sp|P80513|MANF_BOVIN
Mesencephalic astrocyte-derived neurotrophic factor
Search

MANF

0.97	Mesencephalic astrocyte-derived neurotrophic factor

0.75	GO:0071542	dopaminergic neuron differentiation
0.61	GO:0031175	neuron projection development
0.46	GO:0006986	response to unfolded protein
0.45	GO:0010469	regulation of receptor activity
0.45	GO:0002014	vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure
0.41	GO:0006508	proteolysis
0.41	GO:0007264	small GTPase mediated signal transduction
0.39	GO:0002576	platelet degranulation
0.39	GO:0006886	intracellular protein transport

0.46	GO:0008083	growth factor activity
0.45	GO:0005509	calcium ion binding
0.45	GO:0004222	metalloendopeptidase activity
0.42	GO:0008270	zinc ion binding
0.41	GO:0005085	guanyl-nucleotide exchange factor activity
0.39	GO:0003723	RNA binding

0.59	GO:0005615	extracellular space
0.59	GO:0005783	endoplasmic reticulum
0.43	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0005634	nucleus
0.36	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.45

GO:0004222

sp|P80724|BASP1_BOVIN
Brain acid soluble protein 1
Search

BASP1

0.97	Brain abundant membrane attached signal protein 1

0.72	GO:0072112	glomerular visceral epithelial cell differentiation
0.66	GO:0045892	negative regulation of transcription, DNA-templated
0.47	GO:0021762	substantia nigra development
0.44	GO:2001076	positive regulation of metanephric ureteric bud development
0.43	GO:0007356	thorax and anterior abdomen determination
0.43	GO:0060539	diaphragm development
0.42	GO:0072075	metanephric mesenchyme development
0.42	GO:0060231	mesenchymal to epithelial transition
0.42	GO:0060421	positive regulation of heart growth
0.41	GO:0007416	synapse assembly

0.74	GO:0003714	transcription corepressor activity
0.68	GO:0019904	protein domain specific binding
0.65	GO:0044212	transcription regulatory region DNA binding
0.39	GO:0051536	iron-sulfur cluster binding
0.39	GO:0005516	calmodulin binding
0.36	GO:0046872	metal ion binding
0.34	GO:0008995	ribonuclease E activity
0.34	GO:0016757	transferase activity, transferring glycosyl groups
0.34	GO:0042834	peptidoglycan binding
0.34	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity

0.72	GO:0008180	COP9 signalosome
0.68	GO:0016607	nuclear speck
0.66	GO:0030054	cell junction
0.54	GO:0030426	growth cone
0.53	GO:0005886	plasma membrane
0.46	GO:0005737	cytoplasm
0.44	GO:0070062	extracellular exosome
0.41	GO:0048786	presynaptic active zone
0.41	GO:0005856	cytoskeleton
0.39	GO:0098562	cytoplasmic side of membrane

0.34

GO:0016757

sp|P80746|ITAV_BOVIN
Integrin alpha-V
Search

ITGAV

0.88	Alpha v integrin subunit variant

0.78	GO:0007229	integrin-mediated signaling pathway
0.71	GO:0007155	cell adhesion
0.65	GO:2000536	negative regulation of entry of bacterium into host cell
0.64	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process
0.63	GO:0038027	apolipoprotein A-I-mediated signaling pathway
0.63	GO:0038044	transforming growth factor-beta secretion
0.63	GO:0050748	negative regulation of lipoprotein metabolic process
0.62	GO:0010745	negative regulation of macrophage derived foam cell differentiation
0.62	GO:0010888	negative regulation of lipid storage
0.61	GO:0032369	negative regulation of lipid transport

0.64	GO:1990430	extracellular matrix protein binding
0.64	GO:0038132	neuregulin binding
0.63	GO:0019960	C-X3-C chemokine binding
0.62	GO:0031994	insulin-like growth factor I binding
0.62	GO:0001968	fibronectin binding
0.61	GO:0001846	opsonin binding
0.61	GO:0017134	fibroblast growth factor binding
0.60	GO:0005080	protein kinase C binding
0.59	GO:0005178	integrin binding
0.59	GO:0050840	extracellular matrix binding

0.79	GO:0008305	integrin complex
0.64	GO:0035868	alphav-beta3 integrin-HMGB1 complex
0.63	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex
0.62	GO:0031258	lamellipodium membrane
0.62	GO:0031528	microvillus membrane
0.62	GO:0031527	filopodium membrane
0.60	GO:0032587	ruffle membrane
0.58	GO:0005925	focal adhesion
0.56	GO:0009897	external side of plasma membrane
0.50	GO:0005829	cytosol

sp|P80747|ITB5_BOVIN
Integrin beta-5
Search

ITGB5

0.68	Integrin beta

0.80	GO:0007229	integrin-mediated signaling pathway
0.72	GO:0007155	cell adhesion
0.59	GO:0043149	stress fiber assembly
0.57	GO:0035987	endodermal cell differentiation
0.56	GO:0007179	transforming growth factor beta receptor signaling pathway
0.37	GO:0060055	angiogenesis involved in wound healing
0.37	GO:0007044	cell-substrate junction assembly
0.37	GO:0030168	platelet activation
0.36	GO:0030334	regulation of cell migration
0.36	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent

0.65	GO:0004872	receptor activity
0.36	GO:0005178	integrin binding
0.36	GO:0104005	hijacked molecular function
0.34	GO:0005080	protein kinase C binding
0.34	GO:0005509	calcium ion binding

0.81	GO:0008305	integrin complex
0.52	GO:0009986	cell surface
0.37	GO:0005925	focal adhesion
0.35	GO:0045335	phagocytic vesicle
0.35	GO:0070062	extracellular exosome
0.35	GO:0035866	alphav-beta3 integrin-PKCalpha complex
0.35	GO:0031252	cell leading edge
0.35	GO:0071133	alpha9-beta1 integrin-ADAM8 complex
0.34	GO:0016324	apical plasma membrane
0.33	GO:0098552	side of membrane

sp|P80929|ANG2_BOVIN
Angiogenin-2
Search

ANG

0.97	Angiogenin ribonuclease 2

0.68	GO:0032431	activation of phospholipase A2 activity
0.67	GO:0006651	diacylglycerol biosynthetic process
0.66	GO:0007202	activation of phospholipase C activity
0.64	GO:0048662	negative regulation of smooth muscle cell proliferation
0.64	GO:0009303	rRNA transcription
0.63	GO:0001938	positive regulation of endothelial cell proliferation
0.63	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.63	GO:0001525	angiogenesis
0.62	GO:0050714	positive regulation of protein secretion
0.61	GO:0001666	response to hypoxia

0.65	GO:0004519	endonuclease activity
0.61	GO:0008201	heparin binding
0.57	GO:0004540	ribonuclease activity
0.57	GO:0042803	protein homodimerization activity
0.56	GO:0003779	actin binding
0.55	GO:0005102	receptor binding
0.55	GO:0005507	copper ion binding
0.51	GO:0003676	nucleic acid binding
0.49	GO:0042277	peptide binding

0.68	GO:0032311	angiogenin-PRI complex
0.65	GO:0005605	basal lamina
0.56	GO:0005615	extracellular space
0.54	GO:0005730	nucleolus
0.54	GO:0031982	vesicle
0.47	GO:0030426	growth cone
0.46	GO:0043025	neuronal cell body
0.44	GO:0044444	cytoplasmic part
0.40	GO:0043230	extracellular organelle
0.30	GO:0016020	membrane

sp|P81019|SFP4_BOVIN
Seminal plasma protein BSP-30 kDa
Search

0.95	Seminal plasma protein BSP-30 kDa

0.72	GO:0019953	sexual reproduction
0.70	GO:1902492	positive regulation of sperm capacitation
0.67	GO:0048469	cell maturation
0.64	GO:0022412	cellular process involved in reproduction in multicellular organism
0.64	GO:0033700	phospholipid efflux
0.63	GO:0048609	multicellular organismal reproductive process
0.63	GO:0003006	developmental process involved in reproduction
0.46	GO:0030574	collagen catabolic process
0.45	GO:0050900	leukocyte migration
0.45	GO:0001503	ossification

0.75	GO:0008201	heparin binding
0.44	GO:0008237	metallopeptidase activity
0.40	GO:0004175	endopeptidase activity
0.39	GO:0008270	zinc ion binding
0.38	GO:0005509	calcium ion binding

0.69	GO:0009986	cell surface
0.61	GO:0044421	extracellular region part
0.30	GO:0031224	intrinsic component of membrane

sp|P81103|VA0E1_BOVIN
V-type proton ATPase subunit e 1
Search

ATP6V0E1

0.68	V-type proton ATPase subunit

0.76	GO:0015991	ATP hydrolysis coupled proton transport
0.37	GO:0090383	phagosome acidification
0.37	GO:0010243	response to organonitrogen compound
0.37	GO:0033572	transferrin transport
0.36	GO:0007035	vacuolar acidification
0.36	GO:0016241	regulation of macroautophagy
0.36	GO:1901700	response to oxygen-containing compound
0.36	GO:1901699	cellular response to nitrogen compound
0.36	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.35	GO:0032870	cellular response to hormone stimulus

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.56	GO:0036442	proton-exporting ATPase activity
0.51	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
0.33	GO:0046983	protein dimerization activity
0.32	GO:0003676	nucleic acid binding

0.78	GO:0033179	proton-transporting V-type ATPase, V0 domain
0.37	GO:0030670	phagocytic vesicle membrane
0.36	GO:0010008	endosome membrane
0.33	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

sp|P81125|SNAA_BOVIN
Alpha-soluble NSF attachment protein
Search

NAPA

0.88	N-ethylmaleimide sensitive fusion protein attachment protein alpha

0.69	GO:0006886	intracellular protein transport
0.64	GO:0035494	SNARE complex disassembly
0.64	GO:0010807	regulation of synaptic vesicle priming
0.61	GO:0035249	synaptic transmission, glutamatergic
0.53	GO:0045176	apical protein localization
0.50	GO:0007420	brain development
0.49	GO:0030182	neuron differentiation
0.45	GO:0061025	membrane fusion
0.39	GO:0043462	regulation of ATPase activity
0.37	GO:0051345	positive regulation of hydrolase activity

0.61	GO:0019905	syntaxin binding
0.54	GO:0005483	soluble NSF attachment protein activity
0.37	GO:0032403	protein complex binding
0.32	GO:0003677	DNA binding

0.64	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex
0.58	GO:0043209	myelin sheath
0.48	GO:0005774	vacuolar membrane
0.39	GO:0043195	terminal bouton
0.38	GO:0070062	extracellular exosome
0.34	GO:0005886	plasma membrane
0.34	GO:0000139	Golgi membrane
0.33	GO:0005829	cytosol
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|P81126|SNAB_BOVIN
Beta-soluble NSF attachment protein
Search

NAPB

0.86	N-ethylmaleimide-sensitive factor attachment protein, beta a

0.69	GO:0006886	intracellular protein transport
0.64	GO:0035494	SNARE complex disassembly
0.63	GO:0010807	regulation of synaptic vesicle priming
0.61	GO:0035249	synaptic transmission, glutamatergic
0.50	GO:0045176	apical protein localization
0.47	GO:0007420	brain development
0.46	GO:0030182	neuron differentiation
0.45	GO:0061025	membrane fusion
0.38	GO:0043462	regulation of ATPase activity
0.38	GO:0045494	photoreceptor cell maintenance

0.60	GO:0019905	syntaxin binding
0.53	GO:0005483	soluble NSF attachment protein activity
0.37	GO:0032403	protein complex binding
0.35	GO:0008081	phosphoric diester hydrolase activity
0.34	GO:0004620	phospholipase activity
0.33	GO:0005509	calcium ion binding
0.33	GO:0004871	signal transducer activity

0.63	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex
0.58	GO:0043209	myelin sheath
0.48	GO:0005774	vacuolar membrane
0.38	GO:0043195	terminal bouton
0.38	GO:0070062	extracellular exosome
0.34	GO:0005886	plasma membrane
0.34	GO:0000139	Golgi membrane
0.33	GO:0005829	cytosol
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.35

GO:0008081

sp|P81127|SNAG_BOVIN
Gamma-soluble NSF attachment protein
Search

NAPG

0.94	N-ethylmaleimide-sensitive factor attachment protein, gamma a

0.69	GO:0006886	intracellular protein transport
0.43	GO:0061025	membrane fusion
0.36	GO:0016192	vesicle-mediated transport
0.34	GO:0050821	protein stabilization
0.34	GO:0006461	protein complex assembly

0.51	GO:0005483	soluble NSF attachment protein activity
0.48	GO:0019905	syntaxin binding

0.51	GO:0043209	myelin sheath
0.48	GO:0031201	SNARE complex
0.47	GO:0005774	vacuolar membrane
0.44	GO:0005739	mitochondrion
0.38	GO:0005764	lysosome
0.37	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

sp|P81134|RENR_BOVIN
Renin receptor
Search

ATP6AP2

0.87	ATPase H+ transporting accessory protein 2

0.73	GO:0032914	positive regulation of transforming growth factor beta1 production
0.70	GO:0021903	rostrocaudal neural tube patterning
0.70	GO:0002003	angiotensin maturation
0.70	GO:0048069	eye pigmentation
0.69	GO:0060323	head morphogenesis
0.67	GO:0030177	positive regulation of Wnt signaling pathway
0.63	GO:0043408	regulation of MAPK cascade
0.51	GO:0035622	intrahepatic bile duct development

0.65	GO:0004872	receptor activity
0.30	GO:0003824	catalytic activity

0.65	GO:0009897	external side of plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P81187|CFAB_BOVIN
Complement factor B
Search

CFB

0.94	Complement factor B

0.82	GO:0006956	complement activation
0.60	GO:0006508	proteolysis
0.54	GO:0002455	humoral immune response mediated by circulating immunoglobulin
0.46	GO:0045087	innate immune response
0.40	GO:2000427	positive regulation of apoptotic cell clearance
0.39	GO:0097066	response to thyroid hormone
0.38	GO:0032496	response to lipopolysaccharide
0.37	GO:0007584	response to nutrient
0.37	GO:0030449	regulation of complement activation
0.35	GO:0008283	cell proliferation

0.69	GO:0004252	serine-type endopeptidase activity
0.36	GO:0001848	complement binding
0.34	GO:0046872	metal ion binding

0.65	GO:0005576	extracellular region
0.38	GO:0031982	vesicle
0.33	GO:0005886	plasma membrane

0.69

GO:0004252

sp|P81264|PRRP_BOVIN
Prolactin-releasing peptide
Search

PRLH

0.97	Prolactin-releasing peptide

0.76	GO:0010469	regulation of receptor activity
0.72	GO:0002021	response to dietary excess
0.72	GO:0042755	eating behavior
0.70	GO:0048483	autonomic nervous system development
0.69	GO:0045444	fat cell differentiation
0.69	GO:0009749	response to glucose
0.69	GO:0040014	regulation of multicellular organism growth
0.68	GO:0032868	response to insulin
0.68	GO:0001894	tissue homeostasis
0.62	GO:0006112	energy reserve metabolic process

0.79	GO:0005179	hormone activity
0.50	GO:0031861	prolactin-releasing peptide receptor binding
0.40	GO:0017137	Rab GTPase binding
0.39	GO:0005148	prolactin receptor binding

0.42	GO:0005576	extracellular region
0.36	GO:0005737	cytoplasm

sp|P81265|PIGR_BOVIN
Polymeric immunoglobulin receptor
Search

PIGR

0.97	Polymeric immunoglobulin receptor

0.79	GO:0002415	immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor
0.75	GO:0038093	Fc receptor signaling pathway
0.74	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste
0.73	GO:0043113	receptor clustering
0.73	GO:0007173	epidermal growth factor receptor signaling pathway
0.43	GO:0001895	retina homeostasis
0.40	GO:0043312	neutrophil degranulation

0.81	GO:0001792	polymeric immunoglobulin receptor activity
0.40	GO:0005154	epidermal growth factor receptor binding

0.67	GO:0043235	receptor complex
0.63	GO:0005615	extracellular space
0.51	GO:0005886	plasma membrane
0.42	GO:1903561	extracellular vesicle
0.41	GO:0035577	azurophil granule membrane
0.39	GO:0055038	recycling endosome membrane
0.38	GO:0030133	transport vesicle
0.30	GO:0016021	integral component of membrane

sp|P81282|CSPG2_BOVIN
Versican core protein
Search

VCAN

0.72

Versican

0.68	GO:0007155	cell adhesion
0.49	GO:0001501	skeletal system development
0.48	GO:0007417	central nervous system development
0.46	GO:0030207	chondroitin sulfate catabolic process
0.46	GO:0030208	dermatan sulfate biosynthetic process
0.44	GO:0030206	chondroitin sulfate biosynthetic process
0.44	GO:0008347	glial cell migration
0.44	GO:0001503	ossification
0.43	GO:0043687	post-translational protein modification
0.43	GO:0030198	extracellular matrix organization

0.79	GO:0005540	hyaluronic acid binding
0.70	GO:0005509	calcium ion binding
0.50	GO:0005201	extracellular matrix structural constituent
0.40	GO:0030246	carbohydrate binding
0.38	GO:0005515	protein binding

0.62	GO:0031012	extracellular matrix
0.61	GO:0005615	extracellular space
0.45	GO:0043202	lysosomal lumen
0.45	GO:0005796	Golgi lumen
0.43	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0016020	membrane

sp|P81287|ANXA5_BOVIN
Annexin A5
Search

ANXA5

0.57

Annexin

0.85	GO:0050819	negative regulation of coagulation
0.49	GO:0010033	response to organic substance
0.42	GO:2000145	regulation of cell motility
0.41	GO:0007596	blood coagulation
0.37	GO:0006816	calcium ion transport
0.36	GO:0055074	calcium ion homeostasis
0.36	GO:0051260	protein homooligomerization
0.36	GO:1902721	negative regulation of prolactin secretion
0.36	GO:0071284	cellular response to lead ion
0.36	GO:0042981	regulation of apoptotic process

0.81	GO:0005544	calcium-dependent phospholipid binding
0.70	GO:0005509	calcium ion binding
0.37	GO:0005515	protein binding
0.36	GO:0035374	chondroitin sulfate binding
0.36	GO:0015085	calcium ion transmembrane transporter activity
0.35	GO:0015485	cholesterol binding
0.35	GO:0004859	phospholipase inhibitor activity
0.35	GO:0005216	ion channel activity
0.35	GO:0017046	peptide hormone binding
0.35	GO:0008201	heparin binding

0.59	GO:0072563	endothelial microparticle
0.53	GO:0009897	external side of plasma membrane
0.38	GO:0005622	intracellular
0.37	GO:0031982	vesicle
0.36	GO:0005925	focal adhesion
0.36	GO:0043230	extracellular organelle
0.35	GO:0014704	intercalated disc
0.35	GO:0043204	perikaryon
0.35	GO:0012505	endomembrane system
0.35	GO:0043679	axon terminus

sp|P81401|VIP_BOVIN
VIP peptides
Search

VIP

0.97	Vasoactive intestinal polypeptide

0.76	GO:0010469	regulation of receptor activity
0.75	GO:0070459	prolactin secretion
0.72	GO:0048255	mRNA stabilization
0.60	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.59	GO:0019933	cAMP-mediated signaling
0.54	GO:0045732	positive regulation of protein catabolic process
0.54	GO:0032880	regulation of protein localization
0.44	GO:0007218	neuropeptide signaling pathway
0.42	GO:0007399	nervous system development
0.42	GO:0071651	positive regulation of chemokine (C-C motif) ligand 5 production

0.79	GO:0005179	hormone activity
0.42	GO:0051428	peptide hormone receptor binding
0.36	GO:0031858	pituitary adenylate cyclase-activating polypeptide receptor binding
0.36	GO:0005057	signal transducer activity, downstream of receptor

0.66	GO:0005576	extracellular region
0.38	GO:0005622	intracellular
0.38	GO:0097458	neuron part
0.36	GO:0044297	cell body
0.36	GO:0120025	plasma membrane bounded cell projection
0.34	GO:0044456	synapse part
0.34	GO:0044463	cell projection part
0.30	GO:0016020	membrane

sp|P81425|DPP4_BOVIN
Dipeptidyl peptidase 4
Search

DPP4

0.90	Venom dipeptidylpeptidase IV

0.61

GO:0006508

proteolysis

0.69

GO:0004252

serine-type endopeptidase activity

0.30

GO:0031224

intrinsic component of membrane

0.69

GO:0004252

sp|P81623|ERP29_BOVIN
Endoplasmic reticulum resident protein 29
Search

ERP29

0.97	Endoplasmic reticulum resident protein 29

0.70	GO:0009306	protein secretion
0.67	GO:0000187	activation of MAPK activity
0.67	GO:0050709	negative regulation of protein secretion
0.63	GO:1902235	regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
0.58	GO:0010628	positive regulation of gene expression
0.55	GO:0010629	negative regulation of gene expression
0.48	GO:0006886	intracellular protein transport
0.48	GO:0006457	protein folding
0.37	GO:0043335	protein unfolding
0.37	GO:0034976	response to endoplasmic reticulum stress

0.42	GO:0051087	chaperone binding
0.42	GO:0042803	protein homodimerization activity
0.37	GO:0003756	protein disulfide isomerase activity
0.34	GO:0016887	ATPase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.84	GO:0005788	endoplasmic reticulum lumen
0.71	GO:0042470	melanosome
0.61	GO:0009986	cell surface
0.45	GO:0005790	smooth endoplasmic reticulum
0.42	GO:0030133	transport vesicle
0.39	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.37

EC:5.3.4.1

GO:0003756

sp|P81644|APOA2_BOVIN
Apolipoprotein A-II
Search

APOA2

0.97	Apolipoprotein A-II

0.75	GO:0042157	lipoprotein metabolic process
0.74	GO:0006869	lipid transport
0.71	GO:0060695	negative regulation of cholesterol transporter activity
0.71	GO:0018158	protein oxidation
0.70	GO:0060621	negative regulation of cholesterol import
0.70	GO:0045416	positive regulation of interleukin-8 biosynthetic process
0.70	GO:0034380	high-density lipoprotein particle assembly
0.70	GO:0034374	low-density lipoprotein particle remodeling
0.70	GO:0046340	diacylglycerol catabolic process
0.70	GO:0034370	triglyceride-rich lipoprotein particle remodeling

0.72	GO:0008289	lipid binding
0.71	GO:0070653	high-density lipoprotein particle receptor binding
0.71	GO:0034190	apolipoprotein receptor binding
0.70	GO:0008035	high-density lipoprotein particle binding
0.69	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity
0.68	GO:0050997	quaternary ammonium group binding
0.68	GO:0055102	lipase inhibitor activity
0.67	GO:0017127	cholesterol transporter activity
0.64	GO:0070405	ammonium ion binding
0.64	GO:0043178	alcohol binding

0.75	GO:0034364	high-density lipoprotein particle
0.68	GO:0042627	chylomicron
0.68	GO:0034361	very-low-density lipoprotein particle
0.54	GO:0072562	blood microparticle
0.39	GO:0070062	extracellular exosome
0.37	GO:0005788	endoplasmic reticulum lumen
0.37	GO:0005829	cytosol
0.37	GO:0005769	early endosome

sp|P81947|TBA1B_BOVIN
Tubulin alpha-1B chain
Search

0.53	Tubulin alpha chain

0.71	GO:0007017	microtubule-based process
0.71	GO:0007010	cytoskeleton organization
0.45	GO:0071353	cellular response to interleukin-4
0.36	GO:0030705	cytoskeleton-dependent intracellular transport
0.35	GO:0021634	optic nerve formation
0.35	GO:0097711	ciliary basal body-plasma membrane docking
0.35	GO:0000086	G2/M transition of mitotic cell cycle
0.34	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.34	GO:0018410	C-terminal protein amino acid modification
0.34	GO:0051301	cell division

0.77	GO:0005200	structural constituent of cytoskeleton
0.67	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0032561	guanyl ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0031625	ubiquitin protein ligase binding
0.43	GO:0003725	double-stranded RNA binding
0.36	GO:0019904	protein domain specific binding
0.34	GO:0046982	protein heterodimerization activity
0.33	GO:0046872	metal ion binding

0.73	GO:0005874	microtubule
0.48	GO:0043209	myelin sheath
0.48	GO:0005737	cytoplasm
0.43	GO:0035770	ribonucleoprotein granule
0.42	GO:0031982	vesicle
0.40	GO:0012505	endomembrane system
0.39	GO:0045121	membrane raft
0.38	GO:0043230	extracellular organelle
0.37	GO:0005615	extracellular space
0.34	GO:0030496	midbody

sp|P81948|TBA4A_BOVIN
Tubulin alpha-4A chain
Search

TUBA4A

0.53	Tubulin alpha chain

0.71	GO:0007017	microtubule-based process
0.70	GO:0007010	cytoskeleton organization
0.44	GO:0071353	cellular response to interleukin-4
0.35	GO:0097711	ciliary basal body-plasma membrane docking
0.35	GO:0002576	platelet degranulation
0.35	GO:0000086	G2/M transition of mitotic cell cycle
0.34	GO:0021782	glial cell development
0.34	GO:0042552	myelination
0.34	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.34	GO:0018410	C-terminal protein amino acid modification

0.76	GO:0005200	structural constituent of cytoskeleton
0.67	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0019899	enzyme binding
0.42	GO:0003725	double-stranded RNA binding
0.32	GO:0046872	metal ion binding

0.72	GO:0005874	microtubule
0.47	GO:0005737	cytoplasm
0.42	GO:0043209	myelin sheath
0.38	GO:0070062	extracellular exosome
0.37	GO:0045121	membrane raft
0.34	GO:0030496	midbody

sp|P82292|Z13_BOVIN
Spermadhesin Z13
Search

0.97	Spermadhesin 2

0.83	GO:0007338	single fertilization
0.42	GO:0010469	regulation of receptor activity

0.42

GO:0008083

growth factor activity

0.47

GO:0005576

extracellular region

sp|P82649|RT22_BOVIN
28S ribosomal protein S22, mitochondrial
Search

MRPS22

0.96	Mitochondrial ribosomal protein S22

0.38	GO:0032543	mitochondrial translation
0.35	GO:0006415	translational termination
0.34	GO:0006414	translational elongation

0.49

GO:0003735

structural constituent of ribosome

0.60	GO:0005763	mitochondrial small ribosomal subunit
0.35	GO:0031966	mitochondrial membrane
0.35	GO:0019866	organelle inner membrane

sp|P82669|RT25_BOVIN
28S ribosomal protein S25, mitochondrial
Search

MRPS25

0.97	Mitochondrial ribosomal protein S25

0.39	GO:0032543	mitochondrial translation
0.35	GO:0006415	translational termination
0.34	GO:0006414	translational elongation

0.44	GO:0003735	structural constituent of ribosome
0.34	GO:0046872	metal ion binding
0.33	GO:0016787	hydrolase activity
0.32	GO:0003676	nucleic acid binding

0.55	GO:0005840	ribosome
0.48	GO:0005739	mitochondrion
0.37	GO:0031974	membrane-enclosed lumen
0.36	GO:0044446	intracellular organelle part
0.35	GO:0031090	organelle membrane
0.35	GO:0031975	envelope
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0016787

sp|P82670|RT10_BOVIN
28S ribosomal protein S10, mitochondrial
Search

MRPS10

0.95	Mitochondrial ribosomal protein S10

0.52	GO:0043043	peptide biosynthetic process
0.49	GO:0044267	cellular protein metabolic process
0.48	GO:0010467	gene expression
0.47	GO:0009059	macromolecule biosynthetic process
0.34	GO:0043624	cellular protein complex disassembly

0.55	GO:0003735	structural constituent of ribosome
0.33	GO:0005509	calcium ion binding
0.32	GO:0003723	RNA binding
0.32	GO:0016787	hydrolase activity

0.61	GO:0005840	ribosome
0.54	GO:0005759	mitochondrial matrix
0.35	GO:0031966	mitochondrial membrane
0.35	GO:0019866	organelle inner membrane
0.32	GO:0005730	nucleolus

0.32

GO:0016787

sp|P82708|RET5_BOVIN
Retinol-binding protein 5
Search

RBP5

0.97	Cellular retinol-binding protein III

0.70	GO:0006776	vitamin A metabolic process
0.69	GO:0002138	retinoic acid biosynthetic process
0.50	GO:0033189	response to vitamin A
0.49	GO:0030852	regulation of granulocyte differentiation
0.48	GO:0042572	retinol metabolic process
0.37	GO:0055088	lipid homeostasis
0.34	GO:0006958	complement activation, classical pathway
0.33	GO:0009435	NAD biosynthetic process
0.33	GO:0006508	proteolysis

0.72	GO:0008289	lipid binding
0.55	GO:0019842	vitamin binding
0.41	GO:0043178	alcohol binding
0.34	GO:0004252	serine-type endopeptidase activity
0.34	GO:0016779	nucleotidyltransferase activity
0.33	GO:0005509	calcium ion binding
0.33	GO:0005515	protein binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.55	GO:0005829	cytosol
0.47	GO:0005811	lipid droplet
0.44	GO:0005654	nucleoplasm
0.37	GO:0044297	cell body
0.34	GO:0070062	extracellular exosome

0.34

GO:0004252

sp|P82908|RT36_BOVIN
28S ribosomal protein S36, mitochondrial
Search

MRPS36

0.97	Mitochondrial ribosomal protein S36

0.40	GO:0051382	kinetochore assembly
0.40	GO:0070126	mitochondrial translational termination
0.39	GO:0070125	mitochondrial translational elongation

0.36

GO:0003735

structural constituent of ribosome

0.62	GO:0005763	mitochondrial small ribosomal subunit
0.59	GO:0009353	mitochondrial oxoglutarate dehydrogenase complex
0.39	GO:0000776	kinetochore
0.37	GO:0031966	mitochondrial membrane
0.37	GO:0019866	organelle inner membrane
0.36	GO:0005634	nucleus

sp|P82911|RT11_BOVIN
28S ribosomal protein S11, mitochondrial
Search

MRPS11

0.96	Mitochondrial ribosomal protein S11

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.49	GO:0000028	ribosomal small subunit assembly
0.43	GO:0016072	rRNA metabolic process

0.64	GO:0003735	structural constituent of ribosome
0.56	GO:0019843	rRNA binding
0.48	GO:0048027	mRNA 5'-UTR binding

0.61	GO:0005840	ribosome
0.56	GO:0005759	mitochondrial matrix

sp|P82913|RT15_BOVIN
28S ribosomal protein S15, mitochondrial
Search

MRPS15

0.90	Mitochondrial ribosomal protein S15

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.37	GO:0043624	cellular protein complex disassembly

0.64	GO:0003735	structural constituent of ribosome
0.36	GO:0003723	RNA binding

0.65	GO:0005763	mitochondrial small ribosomal subunit
0.58	GO:0005730	nucleolus
0.37	GO:0031966	mitochondrial membrane
0.37	GO:0019866	organelle inner membrane

sp|P82915|RT16_BOVIN
28S ribosomal protein S16, mitochondrial
Search

MRPS16

0.97	Succinate dehydrogenase complex iron sulfur subunit B

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.36	GO:0035176	social behavior
0.35	GO:0032781	positive regulation of ATPase activity
0.34	GO:0043624	cellular protein complex disassembly

0.64	GO:0003735	structural constituent of ribosome
0.35	GO:0031072	heat shock protein binding
0.33	GO:0033925	mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity
0.32	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
0.32	GO:0003723	RNA binding

0.61	GO:0005840	ribosome
0.52	GO:0005759	mitochondrial matrix
0.46	GO:0005829	cytosol
0.35	GO:0031966	mitochondrial membrane
0.35	GO:0019866	organelle inner membrane
0.34	GO:0005615	extracellular space
0.34	GO:0005654	nucleoplasm
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:3.2.1.96

GO:0033925

sp|P82916|RT17_BOVIN
28S ribosomal protein S17, mitochondrial
Search

MRPS17

0.94	Mitochondrial ribosomal protein S17

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.36	GO:0043624	cellular protein complex disassembly
0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression

0.64	GO:0003735	structural constituent of ribosome
0.39	GO:0019843	rRNA binding

0.61	GO:0005840	ribosome
0.45	GO:0005759	mitochondrial matrix
0.36	GO:0031966	mitochondrial membrane
0.36	GO:0019866	organelle inner membrane

sp|P82917|RT18C_BOVIN
28S ribosomal protein S18c, mitochondrial
Search

MRPS18C

0.96	Mitochondrial ribosomal protein S18C

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.34	GO:0043624	cellular protein complex disassembly
0.32	GO:0006629	lipid metabolic process
0.32	GO:0036211	protein modification process
0.32	GO:0055114	oxidation-reduction process

0.64	GO:0003735	structural constituent of ribosome
0.33	GO:0102965	alcohol-forming fatty acyl-CoA reductase activity
0.33	GO:0080019	fatty-acyl-CoA reductase (alcohol-forming) activity
0.33	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0046872	metal ion binding

0.61	GO:0005840	ribosome
0.50	GO:0005759	mitochondrial matrix
0.43	GO:0044445	cytosolic part
0.35	GO:0031966	mitochondrial membrane
0.35	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

0.33

KEGG:R03876

GO:0004842

sp|P82918|RT18B_BOVIN
28S ribosomal protein S18b, mitochondrial
Search

MRPS18B

0.97	Mitochondrial ribosomal protein S18B

0.59	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.35	GO:0070507	regulation of microtubule cytoskeleton organization
0.35	GO:0048666	neuron development
0.35	GO:0043624	cellular protein complex disassembly
0.34	GO:0055114	oxidation-reduction process
0.33	GO:0036211	protein modification process

0.63	GO:0003735	structural constituent of ribosome
0.36	GO:0019799	tubulin N-acetyltransferase activity
0.34	GO:0016491	oxidoreductase activity
0.34	GO:0005515	protein binding

0.61	GO:0005840	ribosome
0.56	GO:0005759	mitochondrial matrix
0.56	GO:0030054	cell junction
0.53	GO:0005654	nucleoplasm
0.35	GO:0005905	clathrin-coated pit
0.35	GO:0030424	axon
0.35	GO:0031966	mitochondrial membrane
0.35	GO:0019866	organelle inner membrane
0.35	GO:0005819	spindle
0.34	GO:0005874	microtubule

0.36

EC:2.3.1.108

GO:0019799

sp|P82919|RT18A_BOVIN
28S ribosomal protein S18a, mitochondrial
Search

MRPS18A

0.96	Mitochondrial ribosomal protein S18A

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.35	GO:0043624	cellular protein complex disassembly

0.64	GO:0003735	structural constituent of ribosome
0.33	GO:0046872	metal ion binding

0.61	GO:0005840	ribosome
0.55	GO:0005759	mitochondrial matrix
0.44	GO:0044445	cytosolic part
0.35	GO:0031966	mitochondrial membrane
0.35	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P82920|RT21_BOVIN
28S ribosomal protein S21, mitochondrial
Search

MRPS21

0.97	Mitochondrial ribosomal protein S21

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.34	GO:0043624	cellular protein complex disassembly
0.34	GO:0032922	circadian regulation of gene expression
0.33	GO:0016071	mRNA metabolic process

0.64	GO:0003735	structural constituent of ribosome
0.34	GO:0003723	RNA binding
0.33	GO:0000976	transcription regulatory region sequence-specific DNA binding
0.32	GO:0016787	hydrolase activity

0.61	GO:0005840	ribosome
0.43	GO:0044446	intracellular organelle part
0.43	GO:0031090	organelle membrane
0.43	GO:0005739	mitochondrion
0.42	GO:0031975	envelope
0.37	GO:0031974	membrane-enclosed lumen
0.34	GO:0120114	Sm-like protein family complex
0.33	GO:0019013	viral nucleocapsid
0.33	GO:0005634	nucleus

0.32

GO:0016787

sp|P82922|RT29_BOVIN
28S ribosomal protein S29, mitochondrial
Search

DAP3

0.93	Death associated protein 3

0.77	GO:0006915	apoptotic process
0.42	GO:0001666	response to hypoxia
0.38	GO:0007005	mitochondrion organization
0.37	GO:0032543	mitochondrial translation
0.34	GO:0006415	translational termination
0.34	GO:0006414	translational elongation
0.33	GO:0007165	signal transduction

0.42	GO:0003735	structural constituent of ribosome
0.35	GO:0003723	RNA binding
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0019001	guanyl nucleotide binding
0.33	GO:0005515	protein binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003677	DNA binding

0.79	GO:0005761	mitochondrial ribosome
0.70	GO:0015935	small ribosomal subunit
0.50	GO:0005654	nucleoplasm
0.34	GO:0031966	mitochondrial membrane
0.34	GO:0019866	organelle inner membrane

sp|P82923|RT02_BOVIN
28S ribosomal protein S2, mitochondrial
Search

MRPS2

0.95	Mitochondrial ribosomal protein S2

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.34	GO:0043624	cellular protein complex disassembly

0.64	GO:0003735	structural constituent of ribosome
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0019001	guanyl nucleotide binding
0.32	GO:0003723	RNA binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.70	GO:0015935	small ribosomal subunit
0.52	GO:0005761	mitochondrial ribosome
0.36	GO:0031080	nuclear pore outer ring
0.34	GO:0031966	mitochondrial membrane
0.34	GO:0019866	organelle inner membrane

sp|P82924|RT30_BOVIN
28S ribosomal protein S30, mitochondrial
Search

MRPS30

0.94	Mitochondrial ribosomal protein S30

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.35	GO:0006915	apoptotic process
0.35	GO:0043624	cellular protein complex disassembly

0.64	GO:0003735	structural constituent of ribosome
0.34	GO:0003723	RNA binding

0.61	GO:0005840	ribosome
0.61	GO:0005739	mitochondrion
0.35	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

sp|P82925|RT31_BOVIN
28S ribosomal protein S31, mitochondrial
Search

MRPS31

0.96	Mitochondrial ribosomal protein S31

0.36	GO:0032543	mitochondrial translation
0.35	GO:0006415	translational termination
0.34	GO:0006414	translational elongation
0.33	GO:0006413	translational initiation
0.33	GO:0035335	peptidyl-tyrosine dephosphorylation

0.64	GO:0003735	structural constituent of ribosome
0.53	GO:0019904	protein domain specific binding
0.35	GO:0003723	RNA binding
0.33	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.33	GO:0004725	protein tyrosine phosphatase activity

0.82	GO:0005763	mitochondrial small ribosomal subunit
0.51	GO:0005730	nucleolus
0.35	GO:0031966	mitochondrial membrane
0.35	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:3.1.3

GO:0008138

sp|P82926|RT33_BOVIN
28S ribosomal protein S33, mitochondrial
Search

MRPS33

0.94	Mitochondrial ribosomal protein S33

0.36	GO:0070126	mitochondrial translational termination
0.36	GO:0070125	mitochondrial translational elongation

0.35

GO:0003735

structural constituent of ribosome

0.56	GO:0005840	ribosome
0.49	GO:0005739	mitochondrion
0.37	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part
0.35	GO:0031090	organelle membrane
0.35	GO:0031975	envelope

sp|P82927|RM42_BOVIN
39S ribosomal protein L42, mitochondrial
Search

MRPL42

0.95	Mitochondrial ribosomal protein L42

0.38	GO:0070126	mitochondrial translational termination
0.37	GO:0070125	mitochondrial translational elongation
0.35	GO:0046426	negative regulation of JAK-STAT cascade
0.34	GO:0001558	regulation of cell growth
0.34	GO:0016567	protein ubiquitination
0.33	GO:0006886	intracellular protein transport
0.33	GO:0035556	intracellular signal transduction

0.35	GO:0003723	RNA binding
0.35	GO:0008269	JAK pathway signal transduction adaptor activity
0.35	GO:0005159	insulin-like growth factor receptor binding
0.34	GO:0003735	structural constituent of ribosome
0.34	GO:0008536	Ran GTPase binding

0.60	GO:0005840	ribosome
0.55	GO:0005759	mitochondrial matrix
0.45	GO:0005886	plasma membrane
0.36	GO:0031966	mitochondrial membrane
0.36	GO:0019866	organelle inner membrane
0.33	GO:0005634	nucleus

sp|P82928|RT28_BOVIN
28S ribosomal protein S28, mitochondrial
Search

MRPS28

0.97	Mitochondrial ribosomal protein S28

0.37	GO:0070126	mitochondrial translational termination
0.37	GO:0070125	mitochondrial translational elongation
0.36	GO:0008612	peptidyl-lysine modification to peptidyl-hypusine
0.34	GO:0030183	B cell differentiation

0.36	GO:0003723	RNA binding
0.34	GO:0042803	protein homodimerization activity
0.34	GO:0046982	protein heterodimerization activity
0.33	GO:0005509	calcium ion binding

0.58	GO:0005840	ribosome
0.49	GO:0005759	mitochondrial matrix
0.36	GO:0031966	mitochondrial membrane
0.36	GO:0019866	organelle inner membrane
0.34	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0005783	endoplasmic reticulum
0.30	GO:0031224	intrinsic component of membrane

sp|P82929|RT34_BOVIN
28S ribosomal protein S34, mitochondrial
Search

MRPS34

0.97	Mitochondrial ribosomal protein S34

0.59	GO:0032543	mitochondrial translation
0.36	GO:0006415	translational termination
0.35	GO:0006414	translational elongation

0.64

GO:0003735

structural constituent of ribosome

0.61	GO:0005739	mitochondrion
0.55	GO:0005840	ribosome
0.38	GO:0031974	membrane-enclosed lumen
0.36	GO:0044446	intracellular organelle part
0.36	GO:0031090	organelle membrane
0.35	GO:0031975	envelope

sp|P82931|RT06_BOVIN
28S ribosomal protein S6, mitochondrial
Search

MRPS6

0.97	Mitochondrial ribosomal protein S6

0.60	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.35	GO:0043624	cellular protein complex disassembly
0.33	GO:0055085	transmembrane transport

0.66	GO:0019843	rRNA binding
0.64	GO:0003735	structural constituent of ribosome
0.34	GO:0005515	protein binding
0.33	GO:0022857	transmembrane transporter activity

0.61	GO:0005840	ribosome
0.57	GO:0005759	mitochondrial matrix
0.35	GO:0031966	mitochondrial membrane
0.35	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P82943|REG1_BOVIN
Regakine-1
Search

0.61	C-C motif chemokine

0.82	GO:0060326	cell chemotaxis
0.74	GO:0006955	immune response
0.68	GO:0010469	regulation of receptor activity
0.59	GO:0097529	myeloid leukocyte migration
0.59	GO:0071674	mononuclear cell migration
0.57	GO:0071347	cellular response to interleukin-1
0.57	GO:0072676	lymphocyte migration
0.56	GO:0071356	cellular response to tumor necrosis factor
0.56	GO:0006954	inflammatory response
0.55	GO:0070374	positive regulation of ERK1 and ERK2 cascade

0.84	GO:0008009	chemokine activity
0.60	GO:0048020	CCR chemokine receptor binding
0.54	GO:0016004	phospholipase activator activity
0.48	GO:0008201	heparin binding
0.43	GO:0004672	protein kinase activity

0.68	GO:0005615	extracellular space
0.33	GO:0005622	intracellular

sp|P83095|LACTB_BOVIN
Serine beta-lactamase-like protein LACTB, mitochondrial
Search

LACTB

0.96	Lactamase beta

0.75	GO:0019216	regulation of lipid metabolic process
0.58	GO:0006508	proteolysis
0.40	GO:0006629	lipid metabolic process

0.58	GO:0008233	peptidase activity
0.45	GO:0042802	identical protein binding

0.65	GO:0005829	cytosol
0.58	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.58

GO:0008233

sp|P83107|SSLP1_BOVIN
Secreted seminal-vesicle Ly-6 protein 1
Search

0.97	Secreted seminal-vesicle Ly-6 protein 1

0.66

GO:0005576

extracellular region

sp|P83437|COG5_BOVIN
Conserved oligomeric Golgi complex subunit 5 (Fragments)
Search

0.34	Conserved oligomeric Golgi complex subunit 5 (Fragments)

0.65

GO:0015031

protein transport

0.74	GO:0000139	Golgi membrane
0.68	GO:0005829	cytosol

sp|P83862|OX26_BOVIN
Orexigenic neuropeptide QRFP
Search

QRFP

0.97	Pyroglutamylated RFamide prepropeptide

0.69	GO:0007625	grooming behavior
0.69	GO:0045777	positive regulation of blood pressure
0.68	GO:0060259	regulation of feeding behavior
0.67	GO:0007218	neuropeptide signaling pathway
0.64	GO:0007626	locomotory behavior
0.63	GO:0010469	regulation of receptor activity

0.88	GO:0031854	orexigenic neuropeptide QRFP receptor binding
0.70	GO:0005184	neuropeptide hormone activity

sp|P83939|SCRN1_BOVIN
Secernin-1
Search

SCRN1

0.97	Secernin-1 isoform a

0.61	GO:0006508	proteolysis
0.48	GO:0006887	exocytosis
0.32	GO:0000413	protein peptidyl-prolyl isomerization

0.77	GO:0016805	dipeptidase activity
0.33	GO:0005515	protein binding
0.32	GO:0003755	peptidyl-prolyl cis-trans isomerase activity

0.53	GO:0031965	nuclear membrane
0.34	GO:0005737	cytoplasm

0.77

EC:3.4.13

GO:0016805

sp|P84080|ARF1_BOVIN
ADP-ribosylation factor 1
Search

ARF1

0.70	ADP-ribosylation factor 1 like

0.54	GO:1990386	mitotic cleavage furrow ingression
0.50	GO:0098586	cellular response to virus
0.49	GO:0016192	vesicle-mediated transport
0.48	GO:0006878	cellular copper ion homeostasis
0.41	GO:0060292	long term synaptic depression
0.41	GO:0097061	dendritic spine organization
0.41	GO:0002090	regulation of receptor internalization
0.40	GO:1903337	positive regulation of vacuolar transport
0.40	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation
0.40	GO:1902822	regulation of late endosome to lysosome transport

0.66	GO:0005525	GTP binding
0.47	GO:0019904	protein domain specific binding
0.46	GO:0046982	protein heterodimerization activity
0.43	GO:0000287	magnesium ion binding
0.41	GO:1990583	phospholipase D activator activity
0.38	GO:0019003	GDP binding
0.34	GO:0003924	GTPase activity
0.34	GO:0005057	signal transducer activity, downstream of receptor
0.33	GO:0005102	receptor binding
0.33	GO:0003755	peptidyl-prolyl cis-trans isomerase activity

0.51	GO:0005794	Golgi apparatus
0.49	GO:0030017	sarcomere
0.48	GO:0031252	cell leading edge
0.44	GO:0005829	cytosol
0.41	GO:0048471	perinuclear region of cytoplasm
0.41	GO:0043234	protein complex
0.39	GO:0031982	vesicle
0.39	GO:0014069	postsynaptic density
0.38	GO:0043230	extracellular organelle
0.38	GO:0045211	postsynaptic membrane

0.33

GO:0003755

sp|P84081|ARF2_BOVIN
ADP-ribosylation factor 2
Search

ARF1

0.78	ADP-ribosylation factor 1 like

0.53	GO:1990386	mitotic cleavage furrow ingression
0.49	GO:0098586	cellular response to virus
0.48	GO:0006878	cellular copper ion homeostasis
0.47	GO:0016192	vesicle-mediated transport
0.41	GO:0060292	long term synaptic depression
0.41	GO:0097061	dendritic spine organization
0.40	GO:0002090	regulation of receptor internalization
0.40	GO:1903337	positive regulation of vacuolar transport
0.40	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation
0.40	GO:1902822	regulation of late endosome to lysosome transport

0.66	GO:0005525	GTP binding
0.47	GO:0019904	protein domain specific binding
0.46	GO:0046982	protein heterodimerization activity
0.43	GO:0000287	magnesium ion binding
0.40	GO:1990583	phospholipase D activator activity
0.38	GO:0019003	GDP binding
0.34	GO:0005057	signal transducer activity, downstream of receptor
0.33	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.33	GO:0003723	RNA binding
0.33	GO:0003924	GTPase activity

0.50	GO:0005794	Golgi apparatus
0.48	GO:0030017	sarcomere
0.48	GO:0031252	cell leading edge
0.44	GO:0005829	cytosol
0.41	GO:0043234	protein complex
0.39	GO:0014069	postsynaptic density
0.39	GO:0031982	vesicle
0.38	GO:0043230	extracellular organelle
0.38	GO:0045211	postsynaptic membrane
0.38	GO:0048471	perinuclear region of cytoplasm

0.33

GO:0003755

sp|P84088|CPLX2_BOVIN
Complexin-2
Search

CPLX2

0.95	Complexin 2

0.76	GO:0006836	neurotransmitter transport
0.53	GO:0031915	positive regulation of synaptic plasticity
0.48	GO:0045055	regulated exocytosis
0.48	GO:0030073	insulin secretion
0.48	GO:0048489	synaptic vesicle transport
0.48	GO:0099504	synaptic vesicle cycle
0.48	GO:0099643	signal release from synapse
0.48	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.44	GO:0001505	regulation of neurotransmitter levels
0.39	GO:0002279	mast cell activation involved in immune response

0.84	GO:0019905	syntaxin binding
0.45	GO:0005326	neurotransmitter transporter activity
0.38	GO:0048306	calcium-dependent protein binding

0.48	GO:0031201	SNARE complex
0.47	GO:0098793	presynapse
0.40	GO:0044306	neuron projection terminus
0.40	GO:0033267	axon part
0.40	GO:0005829	cytosol
0.39	GO:0043025	neuronal cell body
0.39	GO:0030425	dendrite
0.39	GO:0042629	mast cell granule
0.34	GO:0030054	cell junction
0.33	GO:0005634	nucleus

sp|P84227|H32_BOVIN
Histone H3.2
Search

0.43	GO:0006334	nucleosome assembly
0.35	GO:0006352	DNA-templated transcription, initiation

0.74	GO:0046982	protein heterodimerization activity
0.55	GO:0003677	DNA binding
0.39	GO:0031491	nucleosome binding

0.75	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.36	GO:0005700	polytene chromosome
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|P84291|BPAP_BOVIN
Pregnancy-associated protein bPAP (Fragments)
Search

0.56	Pregnancy-associated protein bPAP (Fragments)

sp|P84466|ERG7_BOVIN
Lanosterol synthase
Search

LSS

0.69	Terpene cyclase/mutase family member

0.54	GO:0006695	cholesterol biosynthetic process
0.51	GO:0031647	regulation of protein stability

0.66

GO:0016866

intramolecular transferase activity

0.53	GO:0005811	lipid droplet
0.30	GO:0031224	intrinsic component of membrane

0.66

EC:5.4

GO:0016866

sp|P84798|DPOD3_BOVIN
DNA polymerase delta subunit 3
Search

POLD3

0.95	DNA-directed polymerase delta 3 accessory subunit

0.66	GO:0006260	DNA replication
0.64	GO:0006297	nucleotide-excision repair, DNA gap filling
0.37	GO:0042769	DNA damage response, detection of DNA damage
0.37	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion
0.36	GO:0071897	DNA biosynthetic process
0.36	GO:0006301	postreplication repair
0.35	GO:0006283	transcription-coupled nucleotide-excision repair
0.35	GO:0000723	telomere maintenance
0.35	GO:0006266	DNA ligation
0.35	GO:0006298	mismatch repair

0.37	GO:0003887	DNA-directed DNA polymerase activity
0.34	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.38	GO:0030894	replisome
0.38	GO:0042575	DNA polymerase complex
0.38	GO:0043233	organelle lumen
0.34	GO:0005737	cytoplasm

0.37

GO:0003887

sp|P85091|CYFP1_BOVIN
Cytoplasmic FMR1-interacting protein 1 (Fragments)
Search

0.44	Cytoplasmic FMR1-interacting protein 1 (Fragments)

0.85	GO:0030032	lamellipodium assembly
0.85	GO:0031529	ruffle organization
0.85	GO:0048675	axon extension
0.69	GO:0008360	regulation of cell shape

0.85	GO:0048365	Rac GTPase binding
0.78	GO:0051015	actin filament binding

0.85	GO:0005845	mRNA cap binding complex
0.83	GO:0001726	ruffle
0.83	GO:0030027	lamellipodium
0.79	GO:0048471	perinuclear region of cytoplasm
0.77	GO:0043005	neuron projection
0.75	GO:0045202	synapse
0.75	GO:0030054	cell junction

sp|P85100|MYL3_BOVIN
Myosin light chain 3
Search

MYL3

0.94	Myosin light chain 1, cardiac muscle

0.63	GO:0006936	muscle contraction
0.63	GO:0002026	regulation of the force of heart contraction
0.61	GO:0060047	heart contraction
0.54	GO:0055010	ventricular cardiac muscle tissue morphogenesis
0.53	GO:0006942	regulation of striated muscle contraction
0.49	GO:0032781	positive regulation of ATPase activity
0.39	GO:0007519	skeletal muscle tissue development
0.38	GO:0033275	actin-myosin filament sliding
0.33	GO:0051301	cell division
0.33	GO:0006508	proteolysis

0.70	GO:0005509	calcium ion binding
0.61	GO:0003785	actin monomer binding
0.47	GO:0051015	actin filament binding
0.37	GO:0032038	myosin II heavy chain binding
0.37	GO:0003774	motor activity
0.36	GO:0008307	structural constituent of muscle
0.33	GO:0004252	serine-type endopeptidase activity

0.62	GO:0030016	myofibril
0.58	GO:0044449	contractile fiber part
0.43	GO:0016459	myosin complex
0.35	GO:0005829	cytosol

0.33