Queries 16001 to 16678

GO:0004222

tr|H2Y2Z3|H2Y2Z3_CIOIN
Uncharacterized protein
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tr|H2Y2Z4|H2Y2Z4_CIOIN
Uncharacterized protein
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JMJD6

0.47	Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

0.63

GO:0032259

methylation

0.63

GO:0008168

methyltransferase activity

0.30

GO:0044425

membrane part

0.63

GO:0008168

tr|H2Y2Z5|H2Y2Z5_CIOIN
Uncharacterized protein
Search

0.10	Inositol-pentakisphosphate 2-kinase

0.73	GO:0052746	inositol phosphorylation
0.66	GO:0032958	inositol phosphate biosynthetic process

0.85	GO:0035299	inositol pentakisphosphate 2-kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.51

GO:0005634

nucleus

0.85	EC:2.7.1.158	GO:0035299
0.85	KEGG:R05202	GO:0035299

tr|H2Y2Z6|H2Y2Z6_CIOIN
Uncharacterized protein
Search

tr|H2Y2Z7|H2Y2Z7_CIOIN
Uncharacterized protein
Search

tr|H2Y2Z8|H2Y2Z8_CIOIN
Uncharacterized protein
Search

tr|H2Y2Z9|H2Y2Z9_CIOIN
Uncharacterized protein
Search

tr|H2Y300|H2Y300_CIOIN
Uncharacterized protein
Search

0.61	GO:0098655	cation transmembrane transport
0.47	GO:0086010	membrane depolarization during action potential
0.44	GO:0006816	calcium ion transport
0.37	GO:0034765	regulation of ion transmembrane transport
0.36	GO:0050975	sensory perception of touch
0.36	GO:0045475	locomotor rhythm
0.36	GO:0035176	social behavior
0.36	GO:0072347	response to anesthetic
0.36	GO:0008344	adult locomotory behavior
0.36	GO:0042752	regulation of circadian rhythm

0.74	GO:0005261	cation channel activity
0.36	GO:0022832	voltage-gated channel activity
0.36	GO:0022839	ion gated channel activity
0.36	GO:0008381	mechanosensitive ion channel activity
0.36	GO:0015085	calcium ion transmembrane transporter activity
0.35	GO:0022842	narrow pore channel activity
0.34	GO:0005509	calcium ion binding
0.34	GO:0005515	protein binding
0.34	GO:0015081	sodium ion transmembrane transporter activity
0.33	GO:0005198	structural molecule activity

0.38	GO:0005886	plasma membrane
0.36	GO:0034704	calcium channel complex
0.36	GO:0043679	axon terminus
0.35	GO:0043025	neuronal cell body
0.33	GO:0005856	cytoskeleton

tr|H2Y301|H2Y301_CIOIN
Uncharacterized protein
Search

0.34	tropomyosin

0.78	GO:0006936	muscle contraction
0.71	GO:0007015	actin filament organization

0.83	GO:0008307	structural constituent of muscle
0.74	GO:0051015	actin filament binding

0.85	GO:0005862	muscle thin filament tropomyosin
0.78	GO:0005884	actin filament
0.30	GO:0031224	intrinsic component of membrane

tr|H2Y303|H2Y303_CIOIN
Uncharacterized protein
Search

tr|H2Y304|H2Y304_CIOIN
Uncharacterized protein
Search

tr|H2Y305|H2Y305_CIOIN
Uncharacterized protein
Search

tr|H2Y306|H2Y306_CIOIN
Uncharacterized protein
Search

LOC108742113

0.86	DNA replication complex GINS protein PSF3 isoform X1

0.66

GO:0006260

DNA replication

0.61

GO:0005634

nucleus

tr|H2Y307|H2Y307_CIOIN
Uncharacterized protein
Search

TTLL7

0.82	Tubulin tyrosine ligase like 7

0.60	GO:0036211	protein modification process
0.56	GO:0044267	cellular protein metabolic process
0.36	GO:0007399	nervous system development
0.36	GO:0030154	cell differentiation

0.57	GO:0070740	tubulin-glutamic acid ligase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0043014	alpha-tubulin binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0048487	beta-tubulin binding

0.38	GO:0043204	perikaryon
0.37	GO:0030425	dendrite
0.36	GO:0005929	cilium
0.36	GO:0005874	microtubule
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.57

EC:6.3.2

GO:0070740

tr|H2Y308|H2Y308_CIOIN
Uncharacterized protein
Search

tr|H2Y309|H2Y309_CIOIN
Uncharacterized protein
Search

0.13	4-hydroxyphenylpyruvate dioxygenase

0.68	GO:0009072	aromatic amino acid family metabolic process
0.53	GO:0055114	oxidation-reduction process

0.81	GO:0003868	4-hydroxyphenylpyruvate dioxygenase activity
0.51	GO:0046872	metal ion binding

0.81

EC:1.13.11.27

GO:0003868

tr|H2Y310|H2Y310_CIOIN
Uncharacterized protein
Search

tr|H2Y311|H2Y311_CIOIN
Uncharacterized protein
Search

tr|H2Y312|H2Y312_CIOIN
Uncharacterized protein
Search

tr|H2Y313|H2Y313_CIOIN
Uncharacterized protein
Search

0.80	GO:0008543	fibroblast growth factor receptor signaling pathway
0.76	GO:0008284	positive regulation of cell proliferation
0.74	GO:0018108	peptidyl-tyrosine phosphorylation
0.46	GO:2000830	positive regulation of parathyroid hormone secretion
0.46	GO:0010863	positive regulation of phospholipase C activity
0.46	GO:0021769	orbitofrontal cortex development
0.46	GO:0048378	regulation of lateral mesodermal cell fate specification
0.46	GO:0021847	ventricular zone neuroblast division
0.46	GO:1903465	positive regulation of mitotic cell cycle DNA replication
0.46	GO:1904849	positive regulation of cell chemotaxis to fibroblast growth factor

0.84	GO:0005007	fibroblast growth factor-activated receptor activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0090722	receptor-receptor interaction
0.46	GO:0017134	fibroblast growth factor binding
0.41	GO:0042803	protein homodimerization activity
0.41	GO:1901681	sulfur compound binding
0.35	GO:0097493	structural molecule activity conferring elasticity

0.42	GO:0043235	receptor complex
0.41	GO:0005730	nucleolus
0.37	GO:0005886	plasma membrane
0.35	GO:0031410	cytoplasmic vesicle
0.35	GO:0005859	muscle myosin complex
0.35	GO:0005829	cytosol
0.35	GO:0031430	M band
0.34	GO:0030018	Z disc
0.30	GO:0016021	integral component of membrane

tr|H2Y314|H2Y314_CIOIN
Uncharacterized protein
Search

tr|H2Y315|H2Y315_CIOIN
Uncharacterized protein
Search

YAF2

0.84	YY1-associated factor

0.55	GO:1903507	negative regulation of nucleic acid-templated transcription
0.45	GO:0043066	negative regulation of apoptotic process
0.43	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
0.40	GO:0030900	forebrain development
0.40	GO:0050777	negative regulation of immune response
0.39	GO:0045893	positive regulation of transcription, DNA-templated
0.39	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
0.38	GO:0010629	negative regulation of gene expression
0.34	GO:0010623	programmed cell death involved in cell development
0.34	GO:0070317	negative regulation of G0 to G1 transition

0.60	GO:0003714	transcription corepressor activity
0.59	GO:0003713	transcription coactivator activity
0.53	GO:0046872	metal ion binding
0.36	GO:0003677	DNA binding
0.33	GO:0005515	protein binding

0.42	GO:0005654	nucleoplasm
0.38	GO:0005829	cytosol
0.33	GO:0031519	PcG protein complex
0.30	GO:0031224	intrinsic component of membrane

tr|H2Y316|H2Y316_CIOIN
Uncharacterized protein
Search

tr|H2Y318|H2Y318_CIOIN
Uncharacterized protein
Search

0.16	tumor protein D52 isoform X2

0.30

GO:0044425

membrane part

tr|H2Y319|H2Y319_CIOIN
Uncharacterized protein
Search

0.49	GO:0006413	translational initiation
0.48	GO:0051649	establishment of localization in cell
0.47	GO:0070073	clustering of voltage-gated calcium channels
0.47	GO:0070727	cellular macromolecule localization
0.46	GO:0015031	protein transport
0.45	GO:0007274	neuromuscular synaptic transmission
0.44	GO:0048167	regulation of synaptic plasticity
0.42	GO:0006468	protein phosphorylation
0.41	GO:0007264	small GTPase mediated signal transduction
0.40	GO:0006979	response to oxidative stress

0.52	GO:0017137	Rab GTPase binding
0.49	GO:0003743	translation initiation factor activity
0.47	GO:0003924	GTPase activity
0.46	GO:0005525	GTP binding
0.43	GO:0004674	protein serine/threonine kinase activity
0.42	GO:0008658	penicillin binding
0.41	GO:0046872	metal ion binding
0.41	GO:0004601	peroxidase activity
0.39	GO:0030554	adenyl nucleotide binding
0.39	GO:0005088	Ras guanyl-nucleotide exchange factor activity

0.47	GO:0048788	cytoskeleton of presynaptic active zone
0.37	GO:0032783	ELL-EAF complex
0.37	GO:0008021	synaptic vesicle
0.37	GO:0031932	TORC2 complex
0.36	GO:0005777	peroxisome
0.36	GO:0005911	cell-cell junction
0.34	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.43	EC:2.7.11	GO:0004674
0.41	KEGG:R03532	GO:0004601

tr|H2Y320|H2Y320_CIOIN
Uncharacterized protein
Search

MMAB

0.65	Methylmalonic aciduria (Cobalamin deficiency) cblB type

0.81	GO:0008817	cob(I)yrinic acid a,c-diamide adenosyltransferase activity
0.75	GO:0031419	cobalamin binding

0.61

GO:0005739

mitochondrion

0.81

EC:2.5.1.17

GO:0008817

tr|H2Y321|H2Y321_CIOIN
Uncharacterized protein
Search

tr|H2Y322|H2Y322_CIOIN
Uncharacterized protein
Search

tr|H2Y323|H2Y323_CIOIN
Uncharacterized protein
Search

UBE4B

0.88	Ubiquitin conjugation factor E4 B

0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.73	GO:0016567	protein ubiquitination
0.53	GO:0008626	granzyme-mediated apoptotic signaling pathway
0.52	GO:0003222	ventricular trabecula myocardium morphogenesis
0.51	GO:0034976	response to endoplasmic reticulum stress
0.50	GO:0010498	proteasomal protein catabolic process
0.49	GO:0009411	response to UV
0.48	GO:0031175	neuron projection development
0.46	GO:0010243	response to organonitrogen compound
0.33	GO:0006457	protein folding

0.85	GO:0034450	ubiquitin-ubiquitin ligase activity
0.45	GO:0019899	enzyme binding
0.39	GO:0032559	adenyl ribonucleotide binding
0.39	GO:0008144	drug binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0051082	unfolded protein binding

0.76	GO:0000151	ubiquitin ligase complex
0.43	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|H2Y324|H2Y324_CIOIN
Uncharacterized protein
Search

tr|H2Y325|H2Y325_CIOIN
Uncharacterized protein
Search

tr|H2Y326|H2Y326_CIOIN
Uncharacterized protein
Search

0.20	Trichoplein keratin filament-binding protein

0.49	GO:1902018	negative regulation of cilium assembly
0.47	GO:0030308	negative regulation of cell growth
0.45	GO:0006915	apoptotic process

0.79	GO:0005882	intermediate filament
0.48	GO:0045179	apical cortex
0.48	GO:0097539	ciliary transition fiber
0.48	GO:0030057	desmosome
0.45	GO:0005813	centrosome
0.42	GO:0005829	cytosol
0.40	GO:0005739	mitochondrion
0.38	GO:0005886	plasma membrane

tr|H2Y327|H2Y327_CIOIN
Uncharacterized protein
Search

0.55	GO:0035335	peptidyl-tyrosine dephosphorylation
0.48	GO:0003128	heart field specification
0.48	GO:0003181	atrioventricular valve morphogenesis
0.47	GO:0001756	somitogenesis

0.55

GO:0004725

protein tyrosine phosphatase activity

0.54	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

0.55

EC:3.1.3.48

GO:0004725

tr|H2Y328|H2Y328_CIOIN
Uncharacterized protein
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tr|H2Y329|H2Y329_CIOIN
Uncharacterized protein
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tr|H2Y330|H2Y330_CIOIN
Uncharacterized protein
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tr|H2Y331|H2Y331_CIOIN
Uncharacterized protein
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tr|H2Y332|H2Y332_CIOIN
Uncharacterized protein
Search

tr|H2Y333|H2Y333_CIOIN
Uncharacterized protein
Search

tr|H2Y334|H2Y334_CIOIN
Uncharacterized protein
Search

0.42	GO:1900264	positive regulation of DNA-directed DNA polymerase activity
0.41	GO:0006260	DNA replication
0.38	GO:0001172	transcription, RNA-templated
0.37	GO:0007049	cell cycle

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0003689	DNA clamp loader activity
0.40	GO:0043142	single-stranded DNA-dependent ATPase activity
0.38	GO:0003968	RNA-directed 5'-3' RNA polymerase activity
0.38	GO:0004386	helicase activity

0.47	GO:0005663	DNA replication factor C complex
0.40	GO:0031390	Ctf18 RFC-like complex
0.39	GO:0005634	nucleus
0.38	GO:0005829	cytosol
0.37	GO:0031974	membrane-enclosed lumen

0.38

EC:2.7.7.48

GO:0003968

tr|H2Y335|H2Y335_CIOIN
Uncharacterized protein
Search

tr|H2Y336|H2Y336_CIOIN
Uncharacterized protein
Search

tr|H2Y337|H2Y337_CIOIN
Uncharacterized protein
Search

tr|H2Y338|H2Y338_CIOIN
Uncharacterized protein
Search

tr|H2Y339|H2Y339_CIOIN
Uncharacterized protein
Search

tr|H2Y340|H2Y340_CIOIN
Uncharacterized protein
Search

MRPS14

0.61	Mitochondrial ribosomal protein S14

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process

0.64	GO:0003735	structural constituent of ribosome
0.34	GO:0016787	hydrolase activity

0.61	GO:0005840	ribosome
0.46	GO:0005759	mitochondrial matrix

0.34

GO:0016787

tr|H2Y341|H2Y341_CIOIN
Uncharacterized protein
Search

tr|H2Y342|H2Y342_CIOIN
Oxysterol-binding protein
Search

0.28	Oxysterol-binding protein

0.73

GO:0006869

lipid transport

0.37

GO:0015485

cholesterol binding

0.51	GO:0097038	perinuclear endoplasmic reticulum
0.49	GO:0031965	nuclear membrane
0.45	GO:0005829	cytosol
0.40	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

tr|H2Y343|H2Y343_CIOIN
Uncharacterized protein
Search

tr|H2Y344|H2Y344_CIOIN
Uncharacterized protein
Search

tr|H2Y345|H2Y345_CIOIN
Uncharacterized protein
Search

0.10	probable ubiquitin carboxyl-terminal hydrolase FAF-X

0.76	GO:0016579	protein deubiquitination
0.72	GO:0006511	ubiquitin-dependent protein catabolic process
0.47	GO:0048675	axon extension
0.47	GO:0016477	cell migration
0.46	GO:0030509	BMP signaling pathway
0.46	GO:0007179	transforming growth factor beta receptor signaling pathway
0.38	GO:0021698	cerebellar cortex structural organization
0.37	GO:0021766	hippocampus development
0.37	GO:0001701	in utero embryonic development
0.36	GO:0009791	post-embryonic development

0.76	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.48	GO:0070410	co-SMAD binding
0.33	GO:0004197	cysteine-type endopeptidase activity

0.46	GO:0030426	growth cone
0.37	GO:0005737	cytoplasm
0.36	GO:0045177	apical part of cell
0.30	GO:0016020	membrane

0.76

EC:3.4.19.12

GO:0036459

tr|H2Y346|H2Y346_CIOIN
Uncharacterized protein
Search

0.44	Phospholipase A2 (Fragment)

tr|H2Y347|H2Y347_CIOIN
Uncharacterized protein
Search

tr|H2Y349|H2Y349_CIOIN
Uncharacterized protein
Search

tr|H2Y350|H2Y350_CIOIN
Uncharacterized protein
Search

0.73	GO:0097264	self proteolysis
0.58	GO:0007165	signal transduction
0.44	GO:0048731	system development
0.41	GO:0009653	anatomical structure morphogenesis
0.41	GO:0051960	regulation of nervous system development
0.41	GO:0060284	regulation of cell development
0.41	GO:0007155	cell adhesion
0.41	GO:0030154	cell differentiation
0.36	GO:0016358	dendrite development
0.36	GO:0031346	positive regulation of cell projection organization

0.38	GO:0050839	cell adhesion molecule binding
0.37	GO:0042803	protein homodimerization activity
0.37	GO:0046982	protein heterodimerization activity
0.34	GO:0005509	calcium ion binding
0.33	GO:0016757	transferase activity, transferring glycosyl groups

0.63	GO:0005887	integral component of plasma membrane
0.39	GO:0005578	proteinaceous extracellular matrix
0.37	GO:0043005	neuron projection

0.33

GO:0016757

tr|H2Y352|H2Y352_CIOIN
Uncharacterized protein
Search

tr|H2Y353|H2Y353_CIOIN
Uncharacterized protein
Search

tr|H2Y354|H2Y354_CIOIN
Uncharacterized protein
Search

tr|H2Y355|H2Y355_CIOIN
Uncharacterized protein
Search

tr|H2Y356|H2Y356_CIOIN
Uncharacterized protein
Search

tr|H2Y357|H2Y357_CIOIN
Uncharacterized protein
Search

tr|H2Y359|H2Y359_CIOIN
Uncharacterized protein
Search

0.55	General control of amino acid synthesis protein 5-like 2

0.78	GO:0016573	histone acetylation
0.57	GO:0035948	positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter
0.55	GO:0046600	negative regulation of centriole replication
0.50	GO:0018335	protein succinylation
0.49	GO:0018076	N-terminal peptidyl-lysine acetylation
0.49	GO:0045589	regulation of regulatory T cell differentiation
0.49	GO:0010835	regulation of protein ADP-ribosylation
0.48	GO:0007616	long-term memory
0.48	GO:0030901	midbrain development
0.48	GO:1903146	regulation of autophagy of mitochondrion

0.80	GO:0004402	histone acetyltransferase activity
0.54	GO:0042826	histone deacetylase binding
0.51	GO:0003713	transcription coactivator activity
0.51	GO:0106075	peptide N-succinyltransferase activity
0.51	GO:0003682	chromatin binding
0.49	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor
0.49	GO:0008134	transcription factor binding
0.47	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity
0.45	GO:0019901	protein kinase binding
0.44	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.51	GO:0005813	centrosome
0.50	GO:0031248	protein acetyltransferase complex
0.47	GO:0031672	A band
0.47	GO:0042641	actomyosin
0.46	GO:0043233	organelle lumen
0.46	GO:0072686	mitotic spindle
0.46	GO:0031674	I band
0.46	GO:0045252	oxoglutarate dehydrogenase complex
0.45	GO:0000776	kinetochore

0.80

GO:0004402

tr|H2Y360|H2Y360_CIOIN
Annexin
Search

0.52

Annexin

0.40	GO:0051239	regulation of multicellular organismal process
0.40	GO:0051560	mitochondrial calcium ion homeostasis
0.39	GO:0097190	apoptotic signaling pathway
0.39	GO:0006816	calcium ion transport
0.38	GO:0051260	protein homooligomerization
0.36	GO:0048519	negative regulation of biological process
0.36	GO:0034220	ion transmembrane transport
0.35	GO:0009414	response to water deprivation
0.35	GO:0009651	response to salt stress
0.35	GO:0009409	response to cold

0.81	GO:0005544	calcium-dependent phospholipid binding
0.70	GO:0005509	calcium ion binding
0.39	GO:0048306	calcium-dependent protein binding
0.39	GO:0015485	cholesterol binding
0.38	GO:0015276	ligand-gated ion channel activity
0.38	GO:0042803	protein homodimerization activity
0.37	GO:0032550	purine ribonucleoside binding
0.37	GO:0019001	guanyl nucleotide binding
0.35	GO:0032555	purine ribonucleotide binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.39	GO:0031902	late endosome membrane
0.39	GO:0005765	lysosomal membrane
0.38	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0005739	mitochondrion
0.34	GO:0042470	melanosome
0.34	GO:0031981	nuclear lumen
0.34	GO:0034704	calcium channel complex
0.33	GO:0005886	plasma membrane
0.32	GO:0043232	intracellular non-membrane-bounded organelle

0.33

EC:2.1.1.98

GO:0004164

tr|H2Y361|H2Y361_CIOIN
Uncharacterized protein
Search

tr|H2Y362|H2Y362_CIOIN
Uncharacterized protein
Search

tr|H2Y363|H2Y363_CIOIN
Uncharacterized protein
Search

tr|H2Y364|H2Y364_CIOIN
Uncharacterized protein
Search

0.66

GO:0005576

extracellular region

tr|H2Y365|H2Y365_CIOIN
Uncharacterized protein
Search

tr|H2Y366|H2Y366_CIOIN
Uncharacterized protein
Search

tr|H2Y368|H2Y368_CIOIN
Uncharacterized protein
Search

tr|H2Y369|H2Y369_CIOIN
Uncharacterized protein
Search

SLC13A5

0.85	Sodium-dependent citrate transporter

0.73	GO:0006814	sodium ion transport
0.55	GO:0055085	transmembrane transport
0.51	GO:0015744	succinate transport
0.50	GO:0015746	citrate transport
0.33	GO:0008272	sulfate transport
0.33	GO:0006357	regulation of transcription by RNA polymerase II
0.32	GO:0006520	cellular amino acid metabolic process

0.56	GO:0005215	transporter activity
0.33	GO:0001104	RNA polymerase II transcription cofactor activity
0.32	GO:0030170	pyridoxal phosphate binding

0.42	GO:0005887	integral component of plasma membrane
0.34	GO:0016323	basolateral plasma membrane
0.33	GO:0016592	mediator complex

tr|H2Y370|H2Y370_CIOIN
Uncharacterized protein
Search

tr|H2Y371|H2Y371_CIOIN
Uncharacterized protein
Search

0.49	GO:0006906	vesicle fusion
0.45	GO:0006897	endocytosis
0.45	GO:0039694	viral RNA genome replication
0.35	GO:0016189	synaptic vesicle to endosome fusion
0.35	GO:0045022	early endosome to late endosome transport
0.33	GO:0006886	intracellular protein transport
0.32	GO:0035023	regulation of Rho protein signal transduction
0.32	GO:0065009	regulation of molecular function
0.32	GO:0035556	intracellular signal transduction

0.54	GO:0046872	metal ion binding
0.52	GO:0030742	GTP-dependent protein binding
0.50	GO:0005545	1-phosphatidylinositol binding
0.47	GO:0042803	protein homodimerization activity
0.44	GO:0003676	nucleic acid binding
0.34	GO:0005516	calmodulin binding
0.32	GO:0005089	Rho guanyl-nucleotide exchange factor activity

0.51	GO:0005969	serine-pyruvate aminotransferase complex
0.50	GO:0044308	axonal spine
0.48	GO:0005769	early endosome
0.47	GO:0019897	extrinsic component of plasma membrane
0.44	GO:0005829	cytosol
0.38	GO:0055037	recycling endosome
0.37	GO:0070062	extracellular exosome
0.35	GO:0010008	endosome membrane
0.34	GO:0098793	presynapse

tr|H2Y372|H2Y372_CIOIN
Uncharacterized protein
Search

tr|H2Y373|H2Y373_CIOIN
Uncharacterized protein
Search

tr|H2Y374|H2Y374_CIOIN
Uncharacterized protein
Search

0.75	GO:0070649	formin-nucleated actin cable assembly
0.73	GO:2000251	positive regulation of actin cytoskeleton reorganization
0.69	GO:0051016	barbed-end actin filament capping

0.77	GO:0017048	Rho GTPase binding
0.74	GO:0005522	profilin binding
0.74	GO:0003779	actin binding

0.68	GO:0005935	cellular bud neck
0.61	GO:0032153	cell division site

tr|H2Y375|H2Y375_CIOIN
Uncharacterized protein
Search

tr|H2Y376|H2Y376_CIOIN
Uncharacterized protein
Search

tr|H2Y377|H2Y377_CIOIN
Uncharacterized protein
Search

tr|H2Y378|H2Y378_CIOIN
Uncharacterized protein
Search

tr|H2Y379|H2Y379_CIOIN
Uncharacterized protein
Search

RPA2

0.63	Replication protein A 32 kDa subunit

0.64	GO:0006260	DNA replication
0.64	GO:0006310	DNA recombination
0.63	GO:0006281	DNA repair
0.55	GO:2000001	regulation of DNA damage checkpoint
0.54	GO:0010569	regulation of double-strand break repair via homologous recombination
0.54	GO:0034502	protein localization to chromosome
0.54	GO:0031571	mitotic G1 DNA damage checkpoint
0.52	GO:0000723	telomere maintenance
0.37	GO:0000076	DNA replication checkpoint
0.36	GO:0042769	DNA damage response, detection of DNA damage

0.56	GO:0098505	G-rich strand telomeric DNA binding
0.52	GO:0019903	protein phosphatase binding
0.51	GO:0031625	ubiquitin protein ligase binding
0.49	GO:0003684	damaged DNA binding
0.40	GO:0047485	protein N-terminus binding

0.60	GO:0005634	nucleus
0.53	GO:0035861	site of double-strand break
0.51	GO:0000781	chromosome, telomeric region
0.50	GO:0030894	replisome
0.48	GO:0000785	chromatin
0.47	GO:0031974	membrane-enclosed lumen
0.43	GO:0043234	protein complex

tr|H2Y380|H2Y380_CIOIN
Uncharacterized protein
Search

tr|H2Y381|H2Y381_CIOIN
Uncharacterized protein
Search

tr|H2Y382|H2Y382_CIOIN
Uncharacterized protein
Search

0.46	Alpha-ketoglutarate-dependent sulfonate dioxygenase

0.53

GO:0055114

oxidation-reduction process

0.71

GO:0051213

dioxygenase activity

tr|H2Y383|H2Y383_CIOIN
Uncharacterized protein
Search

tr|H2Y384|H2Y384_CIOIN
Uncharacterized protein
Search

tr|H2Y385|H2Y385_CIOIN
Uncharacterized protein
Search

TTLL5

0.68	Tubulin tyrosine ligase like 5

0.61	GO:0007288	sperm axoneme assembly
0.60	GO:0036211	protein modification process
0.57	GO:0009566	fertilization
0.57	GO:0060041	retina development in camera-type eye
0.56	GO:0044267	cellular protein metabolic process

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0016874	ligase activity

0.54	GO:0005813	centrosome
0.54	GO:0005929	cilium
0.50	GO:0005829	cytosol
0.43	GO:0005886	plasma membrane

0.46

GO:0016874

tr|H2Y386|H2Y386_CIOIN
Uncharacterized protein
Search

tr|H2Y387|H2Y387_CIOIN
Uncharacterized protein
Search

tr|H2Y388|H2Y388_CIOIN
Uncharacterized protein
Search

tr|H2Y389|H2Y389_CIOIN
Uncharacterized protein
Search

tr|H2Y390|H2Y390_CIOIN
Uncharacterized protein
Search

tr|H2Y391|H2Y391_CIOIN
Uncharacterized protein
Search

tr|H2Y392|H2Y392_CIOIN
Uncharacterized protein
Search

tr|H2Y393|H2Y393_CIOIN
Uncharacterized protein
Search

tr|H2Y394|H2Y394_CIOIN
Uncharacterized protein
Search

tr|H2Y395|H2Y395_CIOIN
Uncharacterized protein
Search

SPAST

0.86

Spastin

0.72	GO:0031117	positive regulation of microtubule depolymerization
0.70	GO:0051013	microtubule severing
0.69	GO:0034214	protein hexamerization
0.53	GO:0007399	nervous system development
0.52	GO:0030154	cell differentiation
0.50	GO:0022402	cell cycle process
0.49	GO:0000280	nuclear division
0.49	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.48	GO:0051301	cell division
0.48	GO:0000278	mitotic cell cycle

0.71	GO:0008568	microtubule-severing ATPase activity
0.61	GO:0008017	microtubule binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0043014	alpha-tubulin binding
0.43	GO:0048487	beta-tubulin binding
0.34	GO:0042802	identical protein binding
0.34	GO:0032403	protein complex binding

0.62	GO:0005813	centrosome
0.60	GO:0005819	spindle
0.59	GO:0005874	microtubule
0.49	GO:0048471	perinuclear region of cytoplasm
0.49	GO:0033267	axon part
0.48	GO:0005811	lipid droplet
0.46	GO:0031410	cytoplasmic vesicle
0.46	GO:0030496	midbody
0.45	GO:0120111	neuron projection cytoplasm
0.44	GO:0005634	nucleus

0.71

EC:3.6.4.3

GO:0008568

tr|H2Y396|H2Y396_CIOIN
Uncharacterized protein
Search

0.32	Beta-actin (Fragment)

0.77	GO:0090131	mesenchyme migration
0.62	GO:0010628	positive regulation of gene expression
0.46	GO:0072144	glomerular mesangial cell development
0.42	GO:0009615	response to virus
0.41	GO:0014829	vascular smooth muscle contraction
0.40	GO:0008217	regulation of blood pressure
0.36	GO:0060047	heart contraction
0.36	GO:0061873	regulation of hepatic stellate cell contraction
0.36	GO:0061870	positive regulation of hepatic stellate cell migration
0.35	GO:2000491	positive regulation of hepatic stellate cell activation

0.53	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0019901	protein kinase binding
0.34	GO:0005200	structural constituent of cytoskeleton
0.32	GO:0016787	hydrolase activity

0.72	GO:0030175	filopodium
0.70	GO:0030027	lamellipodium
0.69	GO:0044297	cell body
0.54	GO:0032982	myosin filament
0.44	GO:0005737	cytoplasm
0.40	GO:0071944	cell periphery
0.39	GO:0099512	supramolecular fiber
0.38	GO:0070062	extracellular exosome
0.36	GO:0072562	blood microparticle
0.36	GO:0001725	stress fiber

0.32

GO:0016787

tr|H2Y397|H2Y397_CIOIN
Uncharacterized protein
Search

0.11	GRIP1-associated protein 1-like isoform X1

0.73	GO:0042073	intraciliary transport
0.69	GO:0060271	cilium assembly
0.68	GO:0003334	keratinocyte development
0.68	GO:0033630	positive regulation of cell adhesion mediated by integrin
0.64	GO:0050680	negative regulation of epithelial cell proliferation
0.64	GO:0007368	determination of left/right symmetry
0.63	GO:0007219	Notch signaling pathway
0.61	GO:0007507	heart development
0.59	GO:0045944	positive regulation of transcription by RNA polymerase II
0.39	GO:0007010	cytoskeleton organization

0.73	GO:0048487	beta-tubulin binding
0.60	GO:0003682	chromatin binding
0.46	GO:0003777	microtubule motor activity
0.46	GO:0008017	microtubule binding
0.44	GO:0003779	actin binding
0.40	GO:0032559	adenyl ribonucleotide binding
0.40	GO:0008144	drug binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0032403	protein complex binding
0.39	GO:0031625	ubiquitin protein ligase binding

0.73	GO:0030992	intraciliary transport particle B
0.67	GO:0005929	cilium
0.60	GO:0005813	centrosome
0.51	GO:0005634	nucleus
0.43	GO:0016459	myosin complex
0.40	GO:0120038	plasma membrane bounded cell projection part
0.39	GO:0031410	cytoplasmic vesicle
0.39	GO:0005871	kinesin complex
0.38	GO:0000151	ubiquitin ligase complex
0.37	GO:0005874	microtubule

0.37	EC:2.7.10.1	GO:0004714
0.38	KEGG:R03876	GO:0004842

tr|H2Y398|H2Y398_CIOIN
Uncharacterized protein
Search

tr|H2Y399|H2Y399_CIOIN
Uncharacterized protein
Search

tr|H2Y3A0|H2Y3A0_CIOIN
Uncharacterized protein
Search

0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.58	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.55	GO:0016525	negative regulation of angiogenesis
0.54	GO:0001568	blood vessel development
0.53	GO:0030334	regulation of cell migration
0.51	GO:0032526	response to retinoic acid
0.51	GO:0045026	plasma membrane fusion
0.49	GO:2000146	negative regulation of cell motility
0.48	GO:0001701	in utero embryonic development
0.48	GO:2000251	positive regulation of actin cytoskeleton reorganization

0.77	GO:0004713	protein tyrosine kinase activity
0.64	GO:0019199	transmembrane receptor protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0019838	growth factor binding
0.34	GO:0005057	signal transducer activity, downstream of receptor
0.34	GO:0005088	Ras guanyl-nucleotide exchange factor activity

0.52	GO:0005887	integral component of plasma membrane
0.47	GO:0009925	basal plasma membrane
0.47	GO:0097517	contractile actin filament bundle
0.46	GO:0005902	microvillus
0.46	GO:0042641	actomyosin
0.46	GO:0005884	actin filament
0.45	GO:0016324	apical plasma membrane
0.45	GO:0098857	membrane microdomain
0.44	GO:0005911	cell-cell junction
0.44	GO:0009986	cell surface

0.77

EC:2.7.10

GO:0004713

tr|H2Y3A1|H2Y3A1_CIOIN
Uncharacterized protein
Search

BET1

0.85	Blocked early in transport 1 homolog

0.38	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

tr|H2Y3A2|H2Y3A2_CIOIN
Uncharacterized protein
Search

tr|H2Y3A3|H2Y3A3_CIOIN
Uncharacterized protein
Search

CEP131

0.84	Novel protein containing IQ calmodulin-binding motif

0.86	GO:0035735	intraciliary transport involved in cilium assembly
0.55	GO:0010824	regulation of centrosome duplication
0.54	GO:0071539	protein localization to centrosome
0.52	GO:0090316	positive regulation of intracellular protein transport
0.50	GO:0008284	positive regulation of cell proliferation
0.38	GO:1905198	manchette assembly
0.38	GO:1990953	intramanchette transport
0.37	GO:0007288	sperm axoneme assembly
0.36	GO:0097503	sialylation
0.36	GO:1905515	non-motile cilium assembly

0.49	GO:0042803	protein homodimerization activity
0.48	GO:0032403	protein complex binding
0.37	GO:0008373	sialyltransferase activity
0.35	GO:0004842	ubiquitin-protein transferase activity
0.34	GO:0016887	ATPase activity
0.33	GO:0046872	metal ion binding
0.33	GO:0016874	ligase activity
0.31	GO:0005096	GTPase activator activity
0.31	GO:0043565	sequence-specific DNA binding
0.31	GO:0003700	DNA binding transcription factor activity

0.76	GO:0005929	cilium
0.57	GO:0034451	centriolar satellite
0.53	GO:0045171	intercellular bridge
0.49	GO:0120038	plasma membrane bounded cell projection part
0.41	GO:0043231	intracellular membrane-bounded organelle
0.38	GO:0001669	acrosomal vesicle
0.37	GO:0002177	manchette
0.34	GO:0000775	chromosome, centromeric region
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.37	EC:2.4.99	GO:0008373
0.35	KEGG:R03876	GO:0004842

tr|H2Y3A4|H2Y3A4_CIOIN
Uncharacterized protein
Search

0.53	GO:0055114	oxidation-reduction process
0.36	GO:0044550	secondary metabolite biosynthetic process
0.34	GO:0042368	vitamin D biosynthetic process
0.34	GO:0070640	vitamin D3 metabolic process
0.33	GO:0009813	flavonoid biosynthetic process
0.33	GO:0044108	cellular alcohol biosynthetic process
0.33	GO:0042446	hormone biosynthetic process
0.33	GO:0046173	polyol biosynthetic process
0.33	GO:0009733	response to auxin
0.32	GO:0017144	drug metabolic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.63	GO:0020037	heme binding
0.63	GO:0004497	monooxygenase activity
0.63	GO:0005506	iron ion binding
0.34	GO:0030343	vitamin D3 25-hydroxylase activity
0.31	GO:0003676	nucleic acid binding

0.30

GO:0031224

intrinsic component of membrane

0.68

GO:0016705

tr|H2Y3A5|H2Y3A5_CIOIN
Uncharacterized protein
Search

tr|H2Y3A6|H2Y3A6_CIOIN
Uncharacterized protein
Search

0.56	smoothelin

0.85	GO:0060452	positive regulation of cardiac muscle contraction
0.84	GO:0003085	negative regulation of systemic arterial blood pressure
0.48	GO:0006939	smooth muscle contraction
0.46	GO:0007517	muscle organ development

0.49	GO:0003779	actin binding
0.48	GO:0008307	structural constituent of muscle

0.52	GO:0005856	cytoskeleton
0.39	GO:0005737	cytoplasm

tr|H2Y3A7|H2Y3A7_CIOIN
Uncharacterized protein
Search

tr|H2Y3A8|H2Y3A8_CIOIN
Uncharacterized protein
Search

tr|H2Y3A9|H2Y3A9_CIOIN
Uncharacterized protein
Search

0.46

GO:0006508

proteolysis

0.76	GO:0070492	oligosaccharide binding
0.55	GO:0004181	metallocarboxypeptidase activity
0.48	GO:0008270	zinc ion binding
0.38	GO:0005509	calcium ion binding
0.35	GO:0003677	DNA binding

0.38

GO:0005581

collagen trimer

0.55

EC:3.4.17

GO:0004181

tr|H2Y3B0|H2Y3B0_CIOIN
Uncharacterized protein
Search

tr|H2Y3B1|H2Y3B1_CIOIN
Uncharacterized protein
Search

tr|H2Y3B2|H2Y3B2_CIOIN
Uncharacterized protein
Search

tr|H2Y3B3|H2Y3B3_CIOIN
Uncharacterized protein
Search

tr|H2Y3B5|H2Y3B5_CIOIN
Uncharacterized protein
Search

tr|H2Y3B6|H2Y3B6_CIOIN
Uncharacterized protein
Search

tr|H2Y3B7|H2Y3B7_CIOIN
Uncharacterized protein
Search

tr|H2Y3B8|H2Y3B8_CIOIN
Uncharacterized protein
Search

0.10	calcium-responsive transactivator-like

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.52	GO:0050775	positive regulation of dendrite morphogenesis
0.50	GO:0016358	dendrite development
0.37	GO:0016569	covalent chromatin modification
0.36	GO:1902680	positive regulation of RNA biosynthetic process
0.36	GO:0010628	positive regulation of gene expression
0.35	GO:0006351	transcription, DNA-templated
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0032259	methylation

0.79	GO:0003713	transcription coactivator activity
0.34	GO:0005515	protein binding
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0032561	guanyl ribonucleotide binding
0.33	GO:0003677	DNA binding
0.33	GO:0003924	GTPase activity
0.33	GO:0003700	DNA binding transcription factor activity
0.33	GO:0000287	magnesium ion binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0008168	methyltransferase activity

0.50	GO:0071565	nBAF complex
0.49	GO:0000780	condensed nuclear chromosome, centromeric region
0.48	GO:0000776	kinetochore
0.44	GO:0005829	cytosol
0.36	GO:0016604	nuclear body
0.33	GO:0044462	external encapsulating structure part
0.33	GO:0019867	outer membrane
0.33	GO:0030313	cell envelope
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0008168

tr|H2Y3B9|H2Y3B9_CIOIN
Uncharacterized protein
Search

0.74	GO:0007018	microtubule-based movement
0.52	GO:1905832	positive regulation of spindle assembly
0.51	GO:0090235	regulation of metaphase plate congression
0.50	GO:0051656	establishment of organelle localization
0.50	GO:0033962	cytoplasmic mRNA processing body assembly
0.50	GO:0034063	stress granule assembly
0.49	GO:0051653	spindle localization
0.49	GO:0000226	microtubule cytoskeleton organization
0.49	GO:0060236	regulation of mitotic spindle organization
0.49	GO:0032388	positive regulation of intracellular transport

0.75	GO:0003777	microtubule motor activity
0.60	GO:0016887	ATPase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0051959	dynein light intermediate chain binding
0.48	GO:0045503	dynein light chain binding
0.48	GO:0045505	dynein intermediate chain binding
0.35	GO:0003993	acid phosphatase activity

0.75	GO:0030286	dynein complex
0.49	GO:0030175	filopodium
0.47	GO:0005813	centrosome
0.45	GO:0005874	microtubule
0.37	GO:0005737	cytoplasm
0.36	GO:0031012	extracellular matrix
0.36	GO:0070062	extracellular exosome
0.35	GO:0030424	axon
0.35	GO:0012505	endomembrane system
0.35	GO:0002177	manchette

0.60

GO:0016887

tr|H2Y3C0|H2Y3C0_CIOIN
Uncharacterized protein
Search

0.59	Transcription factor protein (Fragment)

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0010719	negative regulation of epithelial to mesenchymal transition
0.50	GO:0030154	cell differentiation
0.49	GO:0051254	positive regulation of RNA metabolic process
0.49	GO:0061144	alveolar secondary septum development
0.49	GO:0060741	prostate gland stromal morphogenesis
0.49	GO:0060738	epithelial-mesenchymal signaling involved in prostate gland development
0.49	GO:0010557	positive regulation of macromolecule biosynthetic process

0.74	GO:0019904	protein domain specific binding
0.71	GO:0008134	transcription factor binding
0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.50	GO:0044212	transcription regulatory region DNA binding
0.44	GO:0003690	double-stranded DNA binding
0.32	GO:0046872	metal ion binding

0.61	GO:0005634	nucleus
0.46	GO:0070013	intracellular organelle lumen
0.46	GO:0005902	microvillus
0.44	GO:0030054	cell junction
0.42	GO:0044446	intracellular organelle part
0.39	GO:0043232	intracellular non-membrane-bounded organelle
0.32	GO:0005737	cytoplasm

tr|H2Y3C1|H2Y3C1_CIOIN
Uncharacterized protein
Search

tr|H2Y3C2|H2Y3C2_CIOIN
Uncharacterized protein
Search

tr|H2Y3C3|H2Y3C3_CIOIN
Uncharacterized protein
Search

0.40	programmed cell death protein 7-like

tr|H2Y3C4|H2Y3C4_CIOIN
Uncharacterized protein
Search

tr|H2Y3C6|H2Y3C6_CIOIN
Uncharacterized protein
Search

0.41	DNA-dependent protein kinase catalytic subunit-like

0.77	GO:0006303	double-strand break repair via nonhomologous end joining
0.63	GO:0006468	protein phosphorylation
0.55	GO:1902400	intracellular signal transduction involved in G1 DNA damage checkpoint
0.55	GO:0002328	pro-B cell differentiation
0.55	GO:0002326	B cell lineage commitment
0.54	GO:0033152	immunoglobulin V(D)J recombination
0.54	GO:1902402	signal transduction involved in mitotic DNA damage checkpoint
0.54	GO:0031571	mitotic G1 DNA damage checkpoint
0.54	GO:0035234	ectopic germ cell programmed cell death
0.54	GO:0002568	somatic diversification of T cell receptor genes

0.86	GO:0004677	DNA-dependent protein kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0003677	DNA binding
0.49	GO:0019904	protein domain specific binding
0.47	GO:0008134	transcription factor binding
0.46	GO:0019899	enzyme binding
0.34	GO:0003723	RNA binding

0.60	GO:0005634	nucleus
0.55	GO:0070419	nonhomologous end joining complex
0.48	GO:0005667	transcription factor complex
0.47	GO:0032993	protein-DNA complex
0.46	GO:0070013	intracellular organelle lumen
0.42	GO:0043232	intracellular non-membrane-bounded organelle
0.42	GO:0044446	intracellular organelle part
0.36	GO:0031012	extracellular matrix
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.86

GO:0004677

tr|H2Y3C7|H2Y3C7_CIOIN
Uncharacterized protein
Search

tr|H2Y3C8|H2Y3C8_CIOIN
Uncharacterized protein
Search

0.30	myb-like protein V

0.30

GO:0044425

membrane part

tr|H2Y3C9|H2Y3C9_CIOIN
Uncharacterized protein
Search

tr|H2Y3D0|H2Y3D0_CIOIN
Uncharacterized protein
Search

0.10	Guanylate-binding protein (Fragment)

0.48	GO:1990809	endoplasmic reticulum tubular network membrane organization
0.46	GO:0007030	Golgi organization
0.44	GO:0051260	protein homooligomerization
0.35	GO:0006888	ER to Golgi vesicle-mediated transport

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0042802	identical protein binding
0.33	GO:0004814	arginine-tRNA ligase activity

0.48	GO:0098826	endoplasmic reticulum tubular network membrane
0.33	GO:0005856	cytoskeleton
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:6.1.1.19

GO:0004814

tr|H2Y3D1|H2Y3D1_CIOIN
Uncharacterized protein
Search

tr|H2Y3D2|H2Y3D2_CIOIN
Uncharacterized protein
Search

0.10	Mediator of RNA polymerase II transcription subunit 7

0.70	GO:0006357	regulation of transcription by RNA polymerase II
0.57	GO:0006351	transcription, DNA-templated
0.51	GO:0019827	stem cell population maintenance
0.36	GO:0016567	protein ubiquitination
0.36	GO:0051173	positive regulation of nitrogen compound metabolic process
0.36	GO:0010604	positive regulation of macromolecule metabolic process
0.36	GO:0031325	positive regulation of cellular metabolic process
0.35	GO:0009891	positive regulation of biosynthetic process
0.35	GO:0045892	negative regulation of transcription, DNA-templated
0.34	GO:0051347	positive regulation of transferase activity

0.78	GO:0001104	RNA polymerase II transcription cofactor activity
0.45	GO:0003713	transcription coactivator activity
0.37	GO:0061630	ubiquitin protein ligase activity
0.35	GO:0030295	protein kinase activator activity
0.34	GO:0005515	protein binding

0.77	GO:0016592	mediator complex
0.50	GO:0005667	transcription factor complex
0.50	GO:0016604	nuclear body
0.40	GO:1990234	transferase complex
0.30	GO:0031224	intrinsic component of membrane

tr|H2Y3D3|H2Y3D3_CIOIN
Uncharacterized protein
Search

tr|H2Y3D4|H2Y3D4_CIOIN
Uncharacterized protein
Search

tr|H2Y3D5|H2Y3D5_CIOIN
Uncharacterized protein
Search

CYSS

0.41	Cysteine--tRNA ligase, mitochondrial

0.78	GO:0006423	cysteinyl-tRNA aminoacylation
0.37	GO:0021828	gonadotrophin-releasing hormone neuronal migration to the hypothalamus
0.34	GO:0010197	polar nucleus fusion
0.34	GO:0042407	cristae formation
0.33	GO:0043067	regulation of programmed cell death

0.79	GO:0004817	cysteine-tRNA ligase activity
0.56	GO:0008270	zinc ion binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0035446	cysteine-glucosaminylinositol ligase activity

0.46	GO:0005737	cytoplasm
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.33	GO:0043231	intracellular membrane-bounded organelle

0.79

EC:6.1.1.16

GO:0004817

tr|H2Y3D7|H2Y3D7_CIOIN
Uncharacterized protein
Search

tr|H2Y3D8|H2Y3D8_CIOIN
Uncharacterized protein
Search

tr|H2Y3D9|H2Y3D9_CIOIN
Uncharacterized protein
Search

GCHFR

0.97	GTP cyclohydrolase I feedback regulator

0.71	GO:0009890	negative regulation of biosynthetic process
0.46	GO:0043105	negative regulation of GTP cyclohydrolase I activity
0.43	GO:0051291	protein heterooligomerization
0.37	GO:0001505	regulation of neurotransmitter levels
0.37	GO:1903426	regulation of reactive oxygen species biosynthetic process
0.36	GO:1903409	reactive oxygen species biosynthetic process
0.35	GO:2001057	reactive nitrogen species metabolic process
0.34	GO:0051186	cofactor metabolic process
0.34	GO:0017144	drug metabolic process
0.33	GO:0031326	regulation of cellular biosynthetic process

0.47	GO:0016787	hydrolase activity
0.46	GO:0044549	GTP cyclohydrolase binding
0.43	GO:0030742	GTP-dependent protein binding
0.40	GO:0016597	amino acid binding
0.40	GO:0004857	enzyme inhibitor activity

0.62	GO:0042470	melanosome
0.60	GO:0031965	nuclear membrane
0.59	GO:0030425	dendrite
0.53	GO:0005654	nucleoplasm
0.41	GO:0005829	cytosol
0.37	GO:0043234	protein complex

0.47

GO:0016787

tr|H2Y3E0|H2Y3E0_CIOIN
Uncharacterized protein
Search

tr|H2Y3E1|H2Y3E1_CIOIN
Uncharacterized protein
Search

0.83	Putative phospholipid-transporting ATPase VA (Fragment)

0.80

GO:0045332

phospholipid translocation

0.81	GO:0004012	phospholipid-translocating ATPase activity
0.64	GO:0000287	magnesium ion binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.38	GO:0005886	plasma membrane
0.36	GO:0005783	endoplasmic reticulum
0.30	GO:0016021	integral component of membrane

0.81

EC:3.6.3.1

GO:0004012

tr|H2Y3E2|H2Y3E2_CIOIN
Uncharacterized protein
Search

tr|H2Y3E3|H2Y3E3_CIOIN
Uncharacterized protein
Search

0.54	GO:0016525	negative regulation of angiogenesis
0.51	GO:0007166	cell surface receptor signaling pathway
0.48	GO:0007186	G-protein coupled receptor signaling pathway
0.47	GO:0007399	nervous system development
0.46	GO:0006508	proteolysis
0.46	GO:0030154	cell differentiation
0.42	GO:0010466	negative regulation of peptidase activity
0.41	GO:0052548	regulation of endopeptidase activity
0.38	GO:0006898	receptor-mediated endocytosis
0.36	GO:1990798	pancreas regeneration

0.49	GO:0004930	G-protein coupled receptor activity
0.48	GO:0004222	metalloendopeptidase activity
0.44	GO:0046872	metal ion binding
0.42	GO:0030414	peptidase inhibitor activity
0.41	GO:0061135	endopeptidase regulator activity
0.40	GO:0005044	scavenger receptor activity
0.34	GO:0038191	neuropilin binding
0.34	GO:0008061	chitin binding
0.34	GO:0002020	protease binding
0.33	GO:0004252	serine-type endopeptidase activity

0.47	GO:0005576	extracellular region
0.33	GO:0005579	membrane attack complex
0.32	GO:0005737	cytoplasm

0.48

GO:0004222

tr|H2Y3E4|H2Y3E4_CIOIN
Uncharacterized protein
Search

tr|H2Y3E5|H2Y3E5_CIOIN
Uncharacterized protein
Search

0.10	fatty acid synthase

0.52	GO:0055114	oxidation-reduction process
0.49	GO:0071353	cellular response to interleukin-4
0.47	GO:0009058	biosynthetic process
0.43	GO:0006631	fatty acid metabolic process
0.41	GO:0032100	positive regulation of appetite
0.41	GO:0030879	mammary gland development
0.39	GO:0006089	lactate metabolic process
0.36	GO:0002943	tRNA dihydrouridine synthesis

0.84	GO:0004317	3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity
0.84	GO:0004313	[acyl-carrier-protein] S-acetyltransferase activity
0.83	GO:0016295	myristoyl-[acyl-carrier-protein] hydrolase activity
0.83	GO:0016296	palmitoyl-[acyl-carrier-protein] hydrolase activity
0.83	GO:0004320	oleoyl-[acyl-carrier-protein] hydrolase activity
0.82	GO:0004319	enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity
0.76	GO:0004314	[acyl-carrier-protein] S-malonyltransferase activity
0.74	GO:0004316	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
0.74	GO:0004315	3-oxoacyl-[acyl-carrier-protein] synthase activity
0.70	GO:0031177	phosphopantetheine binding

0.50	GO:0042587	glycogen granule
0.43	GO:0005794	Golgi apparatus
0.42	GO:0005829	cytosol
0.40	GO:0005739	mitochondrion
0.38	GO:0005886	plasma membrane

0.84	EC:4.2.1.61	GO:0004317
0.84	KEGG:R04462	GO:0004317

tr|H2Y3E6|H2Y3E6_CIOIN
Uncharacterized protein
Search

0.66	Ankyrin and armadillo repeat-containing protein-like

tr|H2Y3E7|H2Y3E7_CIOIN
Uncharacterized protein
Search

RAD54L

0.77	DNA repair and recombination protein RAD54

0.53	GO:0000733	DNA strand renaturation
0.50	GO:0008340	determination of adult lifespan
0.50	GO:0010212	response to ionizing radiation
0.48	GO:0000724	double-strand break repair via homologous recombination
0.45	GO:0042493	response to drug
0.34	GO:0051321	meiotic cell cycle

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0036310	annealing helicase activity
0.39	GO:0008094	DNA-dependent ATPase activity
0.36	GO:0004386	helicase activity
0.34	GO:0003677	DNA binding
0.33	GO:0005515	protein binding
0.32	GO:0046872	metal ion binding

0.46	GO:0005654	nucleoplasm
0.42	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

tr|H2Y3E8|H2Y3E8_CIOIN
Uncharacterized protein
Search

tr|H2Y3E9|H2Y3E9_CIOIN
Uncharacterized protein
Search

tr|H2Y3F1|H2Y3F1_CIOIN
Uncharacterized protein
Search

HOGA1

0.57	N-acetylneuraminate lyase

0.53	GO:0043648	dicarboxylic acid metabolic process
0.52	GO:0009085	lysine biosynthetic process
0.51	GO:0019470	4-hydroxyproline catabolic process
0.48	GO:0009436	glyoxylate catabolic process
0.47	GO:0042866	pyruvate biosynthetic process
0.33	GO:0015711	organic anion transport
0.32	GO:0055085	transmembrane transport

0.62	GO:0016829	lyase activity
0.45	GO:0042803	protein homodimerization activity
0.33	GO:0008514	organic anion transmembrane transporter activity
0.31	GO:0016787	hydrolase activity

0.41	GO:0005737	cytoplasm
0.39	GO:0043231	intracellular membrane-bounded organelle
0.35	GO:0070062	extracellular exosome
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0005887	integral component of plasma membrane
0.32	GO:0044446	intracellular organelle part

0.62

EC:4

GO:0016829

tr|H2Y3F2|H2Y3F2_CIOIN
Uncharacterized protein
Search

0.58	ADP-ribosylation factor

0.40	GO:0006471	protein ADP-ribosylation
0.39	GO:0048749	compound eye development
0.35	GO:0007281	germ cell development
0.35	GO:0009792	embryo development ending in birth or egg hatching
0.35	GO:0016192	vesicle-mediated transport
0.35	GO:0031584	activation of phospholipase D activity
0.35	GO:0008104	protein localization
0.35	GO:0051489	regulation of filopodium assembly
0.35	GO:0060996	dendritic spine development
0.34	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0032561	guanyl ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity
0.34	GO:0005154	epidermal growth factor receptor binding
0.32	GO:0003723	RNA binding

0.45	GO:0005622	intracellular
0.35	GO:0012505	endomembrane system
0.34	GO:0032154	cleavage furrow
0.34	GO:0032587	ruffle membrane
0.34	GO:0043197	dendritic spine
0.34	GO:0043227	membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.40

EC:2.4.2.31

GO:0003956

tr|H2Y3F3|H2Y3F3_CIOIN
Uncharacterized protein
Search

tr|H2Y3F4|H2Y3F4_CIOIN
Uncharacterized protein
Search

tr|H2Y3F5|H2Y3F5_CIOIN
Uncharacterized protein
Search

tr|H2Y3F6|H2Y3F6_CIOIN
Uncharacterized protein
Search

0.53	GO:0043001	Golgi to plasma membrane protein transport
0.52	GO:2001141	regulation of RNA biosynthetic process

0.70	GO:0003713	transcription coactivator activity
0.54	GO:0035254	glutamate receptor binding
0.53	GO:0030165	PDZ domain binding

0.56	GO:0005634	nucleus
0.53	GO:0030672	synaptic vesicle membrane
0.51	GO:0030425	dendrite
0.51	GO:0005802	trans-Golgi network

tr|H2Y3F7|H2Y3F7_CIOIN
Uncharacterized protein
Search

0.93	leukotriene-B4 omega-hydroxylase 3

0.53	GO:0055114	oxidation-reduction process
0.33	GO:0005992	trehalose biosynthetic process
0.33	GO:0015074	DNA integration

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.66	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.32	GO:0008270	zinc ion binding
0.32	GO:0003676	nucleic acid binding

0.30

GO:0031224

intrinsic component of membrane

0.68

GO:0016705

tr|H2Y3F8|H2Y3F8_CIOIN
Uncharacterized protein
Search

tr|H2Y3F9|H2Y3F9_CIOIN
Uncharacterized protein
Search

tr|H2Y3G0|H2Y3G0_CIOIN
Uncharacterized protein
Search

tr|H2Y3G1|H2Y3G1_CIOIN
Uncharacterized protein
Search

0.10	EGF-containing fibulin-like extracellular matrix protein 1

0.46	GO:0060976	coronary vasculature development
0.45	GO:0035904	aorta development
0.45	GO:0003281	ventricular septum development
0.43	GO:0030198	extracellular matrix organization
0.40	GO:0007166	cell surface receptor signaling pathway
0.39	GO:0071560	cellular response to transforming growth factor beta stimulus
0.39	GO:0007596	blood coagulation
0.39	GO:0046879	hormone secretion
0.38	GO:0036363	transforming growth factor beta activation
0.38	GO:1902462	positive regulation of mesenchymal stem cell proliferation

0.69	GO:0005509	calcium ion binding
0.49	GO:0050431	transforming growth factor beta binding
0.48	GO:0050436	microfibril binding
0.46	GO:0005201	extracellular matrix structural constituent
0.38	GO:0030247	polysaccharide binding
0.37	GO:0008061	chitin binding
0.37	GO:0140096	catalytic activity, acting on a protein
0.37	GO:0017171	serine hydrolase activity
0.36	GO:0016504	peptidase activator activity
0.35	GO:0016773	phosphotransferase activity, alcohol group as acceptor

0.51	GO:0031012	extracellular matrix
0.45	GO:0005615	extracellular space
0.42	GO:0099512	supramolecular fiber
0.38	GO:0043234	protein complex
0.35	GO:1903561	extracellular vesicle
0.34	GO:0005938	cell cortex
0.34	GO:0043235	receptor complex
0.34	GO:0030054	cell junction
0.33	GO:0005886	plasma membrane
0.33	GO:0043231	intracellular membrane-bounded organelle

0.35

EC:2.7.1

GO:0016773

tr|H2Y3G2|H2Y3G2_CIOIN
Uncharacterized protein
Search

TMX1

0.73	Thioredoxin domain containing

0.69	GO:0045454	cell redox homeostasis
0.51	GO:0034976	response to endoplasmic reticulum stress
0.43	GO:0006457	protein folding
0.38	GO:0055114	oxidation-reduction process
0.34	GO:0070932	histone H3 deacetylation
0.32	GO:0006351	transcription, DNA-templated
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.49	GO:0003756	protein disulfide isomerase activity
0.45	GO:0015036	disulfide oxidoreductase activity
0.34	GO:0032041	NAD-dependent histone deacetylase activity (H3-K14 specific)

0.47	GO:0005783	endoplasmic reticulum
0.45	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.43	GO:0031984	organelle subcompartment
0.34	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.49

EC:5.3.4.1

GO:0003756

tr|H2Y3G3|H2Y3G3_CIOIN
Uncharacterized protein
Search

tr|H2Y3G4|H2Y3G4_CIOIN
Uncharacterized protein
Search

0.11	mediator of DNA damage checkpoint protein 1-like

tr|H2Y3G5|H2Y3G5_CIOIN
Uncharacterized protein
Search

tr|H2Y3G6|H2Y3G6_CIOIN
Uncharacterized protein
Search

tr|H2Y3G7|H2Y3G7_CIOIN
Uncharacterized protein
Search

tr|H2Y3G8|H2Y3G8_CIOIN
Uncharacterized protein
Search

0.75	GO:1900004	negative regulation of serine-type endopeptidase activity
0.55	GO:0043113	receptor clustering
0.55	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway
0.36	GO:0006508	proteolysis

0.65	GO:0004867	serine-type endopeptidase inhibitor activity
0.56	GO:0043236	laminin binding
0.50	GO:0002162	dystroglycan binding
0.41	GO:0005201	extracellular matrix structural constituent
0.39	GO:0005509	calcium ion binding
0.36	GO:0008233	peptidase activity

0.50	GO:0005605	basal lamina
0.43	GO:0070701	mucus layer
0.42	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.36

EC:3.4

GO:0008233

tr|H2Y3G9|H2Y3G9_CIOIN
Anoctamin
Search

ANO5

0.65

Anoctamin

0.68	GO:0002407	dendritic cell chemotaxis
0.67	GO:0061588	calcium activated phospholipid scrambling
0.66	GO:0030501	positive regulation of bone mineralization
0.63	GO:0034767	positive regulation of ion transmembrane transport
0.63	GO:0007596	blood coagulation
0.61	GO:1902476	chloride transmembrane transport
0.45	GO:0097045	phosphatidylserine exposure on blood platelet
0.45	GO:0002543	activation of blood coagulation via clotting cascade
0.45	GO:0035630	bone mineralization involved in bone maturation
0.44	GO:0045794	negative regulation of cell volume

0.68	GO:0046983	protein dimerization activity
0.48	GO:0061778	intracellular chloride channel activity
0.44	GO:0017128	phospholipid scramblase activity
0.43	GO:0022839	ion gated channel activity
0.43	GO:0008381	mechanosensitive ion channel activity
0.40	GO:0022832	voltage-gated channel activity
0.40	GO:0005261	cation channel activity
0.40	GO:0042802	identical protein binding

0.42	GO:0034707	chloride channel complex
0.39	GO:0005829	cytosol
0.38	GO:0031982	vesicle
0.38	GO:0005886	plasma membrane
0.34	GO:0043230	extracellular organelle
0.33	GO:0009986	cell surface
0.33	GO:0005615	extracellular space

tr|H2Y3H0|H2Y3H0_CIOIN
Uncharacterized protein
Search

tr|H2Y3H1|H2Y3H1_CIOIN
Gap junction protein
Search

GJD2

0.55	Gap junction delta-2 protein (Fragment)

0.60	GO:0007154	cell communication
0.55	GO:0001508	action potential
0.53	GO:0007601	visual perception
0.44	GO:0023052	signaling
0.35	GO:0055085	transmembrane transport
0.34	GO:0043473	pigmentation
0.34	GO:0006811	ion transport

0.41	GO:0005243	gap junction channel activity
0.35	GO:0022832	voltage-gated channel activity
0.35	GO:0022839	ion gated channel activity
0.35	GO:0008381	mechanosensitive ion channel activity
0.33	GO:0005515	protein binding

0.84	GO:0005922	connexin complex
0.30	GO:0031224	intrinsic component of membrane

tr|H2Y3H2|H2Y3H2_CIOIN
Uncharacterized protein
Search

tr|H2Y3H3|H2Y3H3_CIOIN
Uncharacterized protein
Search

tr|H2Y3H4|H2Y3H4_CIOIN
Uncharacterized protein
Search

0.10	Inositol-pentakisphosphate 2-kinase

0.57

GO:0016310

phosphorylation

0.85	GO:0035299	inositol pentakisphosphate 2-kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.85	EC:2.7.1.158	GO:0035299
0.85	KEGG:R05202	GO:0035299

tr|H2Y3H5|H2Y3H5_CIOIN
Uncharacterized protein
Search

0.83

Roughened

0.61	GO:0007165	signal transduction
0.52	GO:2000301	negative regulation of synaptic vesicle exocytosis
0.50	GO:0009888	tissue development
0.50	GO:0071320	cellular response to cAMP
0.49	GO:1901888	regulation of cell junction assembly
0.48	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.47	GO:2000026	regulation of multicellular organismal development
0.47	GO:0006930	substrate-dependent cell migration, cell extension
0.47	GO:0035099	hemocyte migration
0.46	GO:0048468	cell development

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.45	GO:0032403	protein complex binding
0.43	GO:0017016	Ras GTPase binding
0.42	GO:0019003	GDP binding
0.41	GO:0008565	protein transporter activity
0.37	GO:0005085	guanyl-nucleotide exchange factor activity
0.35	GO:0017056	structural constituent of nuclear pore
0.33	GO:0016746	transferase activity, transferring acyl groups

0.46	GO:0032045	guanyl-nucleotide exchange factor complex
0.46	GO:0030054	cell junction
0.45	GO:0043209	myelin sheath
0.44	GO:0048471	perinuclear region of cytoplasm
0.44	GO:0031252	cell leading edge
0.43	GO:0043005	neuron projection
0.40	GO:0005811	lipid droplet
0.39	GO:0005829	cytosol
0.39	GO:0005886	plasma membrane
0.38	GO:0031982	vesicle

0.33

EC:2.3

GO:0016746

tr|H2Y3H6|H2Y3H6_CIOIN
Uncharacterized protein
Search

tr|H2Y3H7|H2Y3H7_CIOIN
Uncharacterized protein
Search

GAL3ST3

0.79	galactose-3-O-sulfotransferase 3

0.73	GO:0009247	glycolipid biosynthetic process
0.44	GO:0006681	galactosylceramide metabolic process
0.43	GO:0046513	ceramide biosynthetic process
0.43	GO:0042552	myelination
0.42	GO:0007283	spermatogenesis
0.35	GO:0030309	poly-N-acetyllactosamine metabolic process
0.34	GO:0030166	proteoglycan biosynthetic process
0.34	GO:0030317	flagellated sperm motility
0.34	GO:0006364	rRNA processing
0.33	GO:0009311	oligosaccharide metabolic process

0.85	GO:0001733	galactosylceramide sulfotransferase activity
0.36	GO:0050698	proteoglycan sulfotransferase activity
0.35	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding
0.34	GO:0005227	calcium activated cation channel activity
0.33	GO:0030246	carbohydrate binding
0.33	GO:0043021	ribonucleoprotein complex binding

0.72	GO:0005794	Golgi apparatus
0.37	GO:0098588	bounding membrane of organelle
0.36	GO:0031984	organelle subcompartment
0.34	GO:0005730	nucleolus
0.34	GO:0036128	CatSper complex
0.34	GO:0005654	nucleoplasm
0.33	GO:0030687	preribosome, large subunit precursor
0.33	GO:0005694	chromosome

0.85

EC:2.8.2.11

GO:0001733

tr|H2Y3H8|H2Y3H8_CIOIN
Uncharacterized protein
Search

NEURL2

0.80	Neuralized E3 ubiquitin protein ligase 2

0.65	GO:0016567	protein ubiquitination
0.62	GO:0035556	intracellular signal transduction
0.39	GO:0045214	sarcomere organization
0.36	GO:0043687	post-translational protein modification
0.34	GO:0032447	protein urmylation
0.33	GO:0034227	tRNA thio-modification
0.33	GO:0002098	tRNA wobble uridine modification

0.34	GO:0005515	protein binding
0.33	GO:0000049	tRNA binding
0.32	GO:0016779	nucleotidyltransferase activity

0.45	GO:0005622	intracellular
0.39	GO:0005927	muscle tendon junction
0.36	GO:1990234	transferase complex

0.32

EC:2.7.7

GO:0016779

tr|H2Y3H9|H2Y3H9_CIOIN
Uncharacterized protein
Search

tr|H2Y3I0|H2Y3I0_CIOIN
Uncharacterized protein
Search

tr|H2Y3I1|H2Y3I1_CIOIN
Uncharacterized protein
Search

tr|H2Y3I2|H2Y3I2_CIOIN
Uncharacterized protein
Search

tr|H2Y3I3|H2Y3I3_CIOIN
Uncharacterized protein
Search

tr|H2Y3I4|H2Y3I4_CIOIN
Uncharacterized protein
Search

tr|H2Y3I6|H2Y3I6_CIOIN
Uncharacterized protein
Search

tr|H2Y3I7|H2Y3I7_CIOIN
Uncharacterized protein
Search

0.77	GO:0002943	tRNA dihydrouridine synthesis
0.53	GO:0055114	oxidation-reduction process
0.35	GO:0006469	negative regulation of protein kinase activity
0.35	GO:0060548	negative regulation of cell death

0.77	GO:0017150	tRNA dihydrouridine synthase activity
0.66	GO:0050660	flavin adenine dinucleotide binding
0.38	GO:0003723	RNA binding
0.35	GO:0004860	protein kinase inhibitor activity
0.32	GO:0016740	transferase activity

0.34	GO:0005829	cytosol
0.33	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.32

EC:2

GO:0016740

tr|H2Y3I8|H2Y3I8_CIOIN
Uncharacterized protein
Search

tr|H2Y3I9|H2Y3I9_CIOIN
Uncharacterized protein
Search

0.75	GO:0043547	positive regulation of GTPase activity
0.73	GO:0007018	microtubule-based movement
0.63	GO:0035556	intracellular signal transduction
0.49	GO:0035385	Roundabout signaling pathway
0.49	GO:0030048	actin filament-based movement
0.46	GO:0035023	regulation of Rho protein signal transduction
0.40	GO:0048869	cellular developmental process
0.39	GO:0048856	anatomical structure development
0.39	GO:0120036	plasma membrane bounded cell projection organization
0.39	GO:0007626	locomotory behavior

0.76	GO:0005096	GTPase activator activity
0.74	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.74	GO:0003779	actin binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0046872	metal ion binding
0.51	GO:0048495	Roundabout binding
0.50	GO:0000146	microfilament motor activity

0.77	GO:0016459	myosin complex
0.48	GO:0005884	actin filament
0.47	GO:0048471	perinuclear region of cytoplasm
0.45	GO:0005938	cell cortex
0.43	GO:0005829	cytosol
0.35	GO:0032433	filopodium tip
0.35	GO:0001726	ruffle
0.35	GO:0030027	lamellipodium
0.30	GO:0031224	intrinsic component of membrane

0.40

GO:0016887

tr|H2Y3J0|H2Y3J0_CIOIN
Uncharacterized protein
Search

tr|H2Y3J1|H2Y3J1_CIOIN
Uncharacterized protein
Search

tr|H2Y3J2|H2Y3J2_CIOIN
Uncharacterized protein
Search

tr|H2Y3J3|H2Y3J3_CIOIN
Uncharacterized protein
Search

tr|H2Y3J4|H2Y3J4_CIOIN
Uncharacterized protein
Search

RFK

0.64	Riboflavin kinase

0.73	GO:0006771	riboflavin metabolic process
0.73	GO:0042727	flavin-containing compound biosynthetic process
0.67	GO:0042364	water-soluble vitamin biosynthetic process
0.57	GO:0016310	phosphorylation
0.50	GO:0033864	positive regulation of NAD(P)H oxidase activity
0.45	GO:0006915	apoptotic process
0.43	GO:0072593	reactive oxygen species metabolic process
0.37	GO:0046444	FMN metabolic process
0.35	GO:0009156	ribonucleoside monophosphate biosynthetic process
0.35	GO:0009260	ribonucleotide biosynthetic process

0.79	GO:0008531	riboflavin kinase activity
0.34	GO:0016779	nucleotidyltransferase activity
0.34	GO:0005515	protein binding
0.33	GO:0046872	metal ion binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0016787	hydrolase activity

0.39	GO:0005739	mitochondrion
0.33	GO:0005829	cytosol
0.32	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.79	EC:2.7.1.26	GO:0008531
0.79	KEGG:R00549	GO:0008531

tr|H2Y3J5|H2Y3J5_CIOIN
Uncharacterized protein
Search

0.63	GO:0032259	methylation
0.34	GO:0006400	tRNA modification
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:0010468	regulation of gene expression
0.32	GO:0044260	cellular macromolecule metabolic process

0.63	GO:0008168	methyltransferase activity
0.34	GO:0140101	catalytic activity, acting on a tRNA
0.34	GO:0003700	DNA binding transcription factor activity

0.38	GO:0005737	cytoplasm
0.35	GO:0034708	methyltransferase complex

0.63

GO:0008168

tr|H2Y3J6|H2Y3J6_CIOIN
Uncharacterized protein
Search

tr|H2Y3J7|H2Y3J7_CIOIN
Uncharacterized protein
Search

0.31	Chymotrypsin BI

0.61	GO:0006508	proteolysis
0.37	GO:0007596	blood coagulation
0.35	GO:0035208	positive regulation of hemocyte proliferation
0.35	GO:0007283	spermatogenesis

0.69	GO:0004252	serine-type endopeptidase activity
0.35	GO:0005509	calcium ion binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003676	nucleic acid binding

0.35	GO:0005576	extracellular region
0.35	GO:0001669	acrosomal vesicle
0.30	GO:0016020	membrane

0.69

GO:0004252

tr|H2Y3J8|H2Y3J8_CIOIN
Uncharacterized protein
Search

0.10	glycerophosphodiester phosphodiesterase domain-containing protein 5-like

0.59	GO:0006629	lipid metabolic process
0.45	GO:0045597	positive regulation of cell differentiation
0.45	GO:0048505	regulation of timing of cell differentiation
0.45	GO:0051240	positive regulation of multicellular organismal process
0.45	GO:0021895	cerebral cortex neuron differentiation
0.44	GO:0021522	spinal cord motor neuron differentiation
0.44	GO:0045746	negative regulation of Notch signaling pathway
0.42	GO:0045664	regulation of neuron differentiation
0.42	GO:0045787	positive regulation of cell cycle
0.42	GO:0031175	neuron projection development

0.72	GO:0008889	glycerophosphodiester phosphodiesterase activity
0.44	GO:0047389	glycerophosphocholine phosphodiesterase activity
0.33	GO:0005515	protein binding

0.44	GO:0097038	perinuclear endoplasmic reticulum
0.44	GO:0120025	plasma membrane bounded cell projection
0.43	GO:0043025	neuronal cell body
0.41	GO:0005884	actin filament
0.40	GO:0031252	cell leading edge
0.35	GO:0005886	plasma membrane
0.35	GO:0030427	site of polarized growth
0.34	GO:0044463	cell projection part
0.33	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.72

EC:3.1.4.46

GO:0008889

tr|H2Y3J9|H2Y3J9_CIOIN
Uncharacterized protein
Search

tr|H2Y3K0|H2Y3K0_CIOIN
Uncharacterized protein
Search

tr|H2Y3K1|H2Y3K1_CIOIN
Uncharacterized protein
Search

tr|H2Y3K2|H2Y3K2_CIOIN
Protein yippee-like
Search

tr|H2Y3K3|H2Y3K3_CIOIN
Uncharacterized protein
Search

tr|H2Y3K4|H2Y3K4_CIOIN
Uncharacterized protein
Search

0.55	GO:0006508	proteolysis
0.51	GO:0007229	integrin-mediated signaling pathway
0.48	GO:0048513	animal organ development
0.46	GO:0090331	negative regulation of platelet aggregation
0.46	GO:0035295	tube development
0.45	GO:0060429	epithelium development
0.45	GO:0001763	morphogenesis of a branching structure
0.45	GO:0072001	renal system development
0.44	GO:0048729	tissue morphogenesis
0.39	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway

0.57	GO:0004222	metalloendopeptidase activity
0.48	GO:0046872	metal ion binding
0.41	GO:0050436	microfibril binding
0.40	GO:0004252	serine-type endopeptidase activity
0.38	GO:0005042	netrin receptor activity
0.37	GO:0005044	scavenger receptor activity
0.36	GO:0004096	catalase activity
0.35	GO:0030414	peptidase inhibitor activity
0.34	GO:0020037	heme binding
0.34	GO:0050840	extracellular matrix binding

0.55	GO:0005576	extracellular region
0.34	GO:0031463	Cul3-RING ubiquitin ligase complex
0.33	GO:0009986	cell surface
0.32	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016020	membrane

0.57	EC:3.4.24	GO:0004222
0.34	KEGG:R03876	GO:0004842

tr|H2Y3K5|H2Y3K5_CIOIN
Uncharacterized protein
Search

tr|H2Y3K6|H2Y3K6_CIOIN
Uncharacterized protein
Search

0.18	solute carrier family 43 member 3-like

0.40

GO:0055085

transmembrane transport

0.30

GO:0044425

membrane part

tr|H2Y3K7|H2Y3K7_CIOIN
Uncharacterized protein
Search

0.13

Ryncolin

0.58	GO:0032501	multicellular organismal process
0.55	GO:0048856	anatomical structure development
0.54	GO:0007219	Notch signaling pathway
0.51	GO:0043066	negative regulation of apoptotic process
0.50	GO:0006898	receptor-mediated endocytosis
0.48	GO:0007599	hemostasis
0.47	GO:0042060	wound healing

0.54

GO:0005044

scavenger receptor activity

0.49	GO:0005615	extracellular space
0.30	GO:0044425	membrane part

tr|H2Y3K8|H2Y3K8_CIOIN
Uncharacterized protein
Search

tr|H2Y3K9|H2Y3K9_CIOIN
Malate dehydrogenase
Search

MDH1

0.46	Malate dehydrogenase

0.78	GO:0006108	malate metabolic process
0.70	GO:0006099	tricarboxylic acid cycle
0.60	GO:0005975	carbohydrate metabolic process
0.48	GO:0006734	NADH metabolic process
0.46	GO:0006107	oxaloacetate metabolic process
0.32	GO:0044283	small molecule biosynthetic process
0.32	GO:1901576	organic substance biosynthetic process

0.79	GO:0030060	L-malate dehydrogenase activity
0.36	GO:0047860	diiodophenylpyruvate reductase activity
0.34	GO:0051287	NAD binding
0.34	GO:0004470	malic enzyme activity
0.33	GO:0005515	protein binding

0.45	GO:0043209	myelin sheath
0.42	GO:0005829	cytosol
0.42	GO:0005739	mitochondrion
0.35	GO:0005615	extracellular space
0.34	GO:1903561	extracellular vesicle
0.30	GO:0016020	membrane

0.79	EC:1.1.1.37	GO:0030060
0.36	KEGG:R03431	GO:0047860

tr|H2Y3L0|H2Y3L0_CIOIN
Uncharacterized protein
Search

tr|H2Y3L1|H2Y3L1_CIOIN
Uncharacterized protein
Search

0.59	GO:1900111	positive regulation of histone H3-K9 dimethylation
0.52	GO:0050965	detection of temperature stimulus involved in sensory perception of pain
0.50	GO:1903691	positive regulation of wound healing, spreading of epidermal cells
0.49	GO:2000394	positive regulation of lamellipodium morphogenesis
0.49	GO:0033601	positive regulation of mammary gland epithelial cell proliferation
0.48	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading
0.48	GO:0007275	multicellular organism development
0.47	GO:1903506	regulation of nucleic acid-templated transcription
0.47	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.47	GO:0010634	positive regulation of epithelial cell migration

0.52	GO:1990226	histone methyltransferase binding
0.51	GO:0003676	nucleic acid binding
0.46	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.45	GO:0008168	methyltransferase activity
0.43	GO:0046872	metal ion binding
0.33	GO:0008234	cysteine-type peptidase activity

0.49	GO:0005634	nucleus
0.42	GO:0043233	organelle lumen
0.39	GO:0043232	intracellular non-membrane-bounded organelle
0.39	GO:0044446	intracellular organelle part
0.35	GO:0070062	extracellular exosome
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.45

GO:0008168

tr|H2Y3L2|H2Y3L2_CIOIN
Uncharacterized protein
Search

0.30

GO:0044425

membrane part

tr|H2Y3L3|H2Y3L3_CIOIN
Uncharacterized protein
Search

0.38	GO:0001558	regulation of cell growth
0.38	GO:0035335	peptidyl-tyrosine dephosphorylation
0.37	GO:0007219	Notch signaling pathway
0.35	GO:0007155	cell adhesion
0.35	GO:0007275	multicellular organism development
0.35	GO:0016310	phosphorylation
0.34	GO:0006508	proteolysis

0.60	GO:0005509	calcium ion binding
0.39	GO:0005520	insulin-like growth factor binding
0.38	GO:0004725	protein tyrosine phosphatase activity
0.35	GO:0016301	kinase activity
0.35	GO:0004222	metalloendopeptidase activity

0.39	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.38

EC:3.1.3.48

GO:0004725

tr|H2Y3L4|H2Y3L4_CIOIN
Uncharacterized protein
Search

tr|H2Y3L5|H2Y3L5_CIOIN
Uncharacterized protein
Search

0.84	GO:0007043	cell-cell junction assembly
0.80	GO:0007507	heart development

0.59

GO:0005509

calcium ion binding

0.30

GO:0044425

membrane part

tr|H2Y3L6|H2Y3L6_CIOIN
Uncharacterized protein
Search

tr|H2Y3L7|H2Y3L7_CIOIN
Uncharacterized protein
Search

tr|H2Y3L8|H2Y3L8_CIOIN
Uncharacterized protein
Search

tr|H2Y3L9|H2Y3L9_CIOIN
Uncharacterized protein
Search

SNU13

0.97	Small nuclear ribonucleoprotein 13

0.67	GO:0042254	ribosome biogenesis
0.48	GO:0000492	box C/D snoRNP assembly
0.46	GO:0007338	single fertilization
0.43	GO:0060415	muscle tissue morphogenesis
0.42	GO:0000398	mRNA splicing, via spliceosome
0.41	GO:0045727	positive regulation of translation
0.41	GO:0007399	nervous system development
0.40	GO:0016072	rRNA metabolic process
0.39	GO:0034470	ncRNA processing
0.38	GO:0043043	peptide biosynthetic process

0.59	GO:0003723	RNA binding
0.47	GO:0051117	ATPase binding
0.34	GO:0046872	metal ion binding
0.33	GO:0008094	DNA-dependent ATPase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0003677	DNA binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.73	GO:0005730	nucleolus
0.61	GO:0030529	intracellular ribonucleoprotein complex
0.43	GO:0120114	Sm-like protein family complex
0.41	GO:0044445	cytosolic part
0.39	GO:0043234	protein complex
0.33	GO:0019013	viral nucleocapsid
0.32	GO:0005886	plasma membrane

tr|H2Y3M0|H2Y3M0_CIOIN
Uncharacterized protein
Search

tr|H2Y3M1|H2Y3M1_CIOIN
Uncharacterized protein
Search

tr|H2Y3M2|H2Y3M2_CIOIN
Uncharacterized protein
Search

tr|H2Y3M3|H2Y3M3_CIOIN
Uncharacterized protein
Search

tr|H2Y3M4|H2Y3M4_CIOIN
Uncharacterized protein
Search

tr|H2Y3M5|H2Y3M5_CIOIN
Uncharacterized protein
Search

tr|H2Y3M6|H2Y3M6_CIOIN
Uncharacterized protein
Search

tr|H2Y3M7|H2Y3M7_CIOIN
Uncharacterized protein
Search

tr|H2Y3M8|H2Y3M8_CIOIN
Uncharacterized protein
Search

tr|H2Y3M9|H2Y3M9_CIOIN
Uncharacterized protein
Search

0.42	AMP-dependent synthetase

0.36	GO:0009695	jasmonic acid biosynthetic process
0.34	GO:0009698	phenylpropanoid metabolic process
0.33	GO:0055114	oxidation-reduction process

0.54	GO:0016874	ligase activity
0.36	GO:0004321	fatty-acyl-CoA synthase activity
0.35	GO:0004497	monooxygenase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.34	GO:0005777	peroxisome
0.33	GO:0043190	ATP-binding cassette (ABC) transporter complex

0.54

GO:0016874

tr|H2Y3N0|H2Y3N0_CIOIN
Uncharacterized protein
Search

0.58

GO:0016311

dephosphorylation

0.59	GO:0016791	phosphatase activity
0.44	GO:0003676	nucleic acid binding

0.47

GO:0005829

cytosol

0.59

EC:3.1.3 EC:3.1.3.41

GO:0016791

tr|H2Y3N1|H2Y3N1_CIOIN
Uncharacterized protein
Search

0.66	EF-hand calcium-binding domain-containing protein 5-like

0.70

GO:0005509

calcium ion binding

tr|H2Y3N2|H2Y3N2_CIOIN
Uncharacterized protein
Search

tr|H2Y3N3|H2Y3N3_CIOIN
Uncharacterized protein
Search

tr|H2Y3N4|H2Y3N4_CIOIN
Uncharacterized protein
Search

tr|H2Y3N5|H2Y3N5_CIOIN
Uncharacterized protein
Search

tr|H2Y3N6|H2Y3N6_CIOIN
Uncharacterized protein
Search

0.11	DNA repair protein XRCC1-like

0.86	GO:0000012	single strand break repair
0.49	GO:1904877	positive regulation of DNA ligase activity
0.48	GO:1903518	positive regulation of single strand break repair
0.48	GO:0010836	negative regulation of protein ADP-ribosylation
0.48	GO:0061819	telomeric DNA-containing double minutes formation
0.48	GO:1905765	negative regulation of protection from non-homologous end joining at telomere
0.48	GO:0050882	voluntary musculoskeletal movement
0.47	GO:0033194	response to hydroperoxide
0.47	GO:1990414	replication-born double-strand break repair via sister chromatid exchange
0.46	GO:0021587	cerebellum morphogenesis

0.73	GO:0003684	damaged DNA binding
0.48	GO:1990599	3' overhang single-stranded DNA endodeoxyribonuclease activity
0.42	GO:0019899	enzyme binding
0.36	GO:0003909	DNA ligase activity
0.36	GO:0010385	double-stranded methylated DNA binding

0.61	GO:0005634	nucleus
0.44	GO:0000781	chromosome, telomeric region
0.43	GO:1990391	DNA repair complex
0.42	GO:0000785	chromatin
0.42	GO:0031974	membrane-enclosed lumen
0.39	GO:0043234	protein complex
0.34	GO:0005739	mitochondrion

0.36

EC:6.5.1

GO:0003909

tr|H2Y3N7|H2Y3N7_CIOIN
Uncharacterized protein
Search

tr|H2Y3N8|H2Y3N8_CIOIN
Uncharacterized protein
Search

tr|H2Y3N9|H2Y3N9_CIOIN
Uncharacterized protein
Search

0.50	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.35	GO:0043312	neutrophil degranulation
0.33	GO:0016032	viral process

0.60	GO:0008270	zinc ion binding
0.52	GO:0016874	ligase activity
0.47	GO:0004842	ubiquitin-protein transferase activity
0.36	GO:0005516	calmodulin binding

0.48	GO:0005813	centrosome
0.45	GO:0005654	nucleoplasm
0.45	GO:0005829	cytosol
0.35	GO:0101003	ficolin-1-rich granule membrane
0.35	GO:0035579	specific granule membrane
0.35	GO:0070821	tertiary granule membrane
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.52	EC:6	GO:0016874
0.47	KEGG:R03876	GO:0004842

tr|H2Y3P0|H2Y3P0_CIOIN
Uncharacterized protein
Search

tr|H2Y3P1|H2Y3P1_CIOIN
Uncharacterized protein
Search

tr|H2Y3P2|H2Y3P2_CIOIN
Uncharacterized protein
Search

tr|H2Y3P3|H2Y3P3_CIOIN
Uncharacterized protein
Search

tr|H2Y3P4|H2Y3P4_CIOIN
Uncharacterized protein
Search

tr|H2Y3P5|H2Y3P5_CIOIN
Uncharacterized protein
Search

0.61	GO:0035767	endothelial cell chemotaxis
0.60	GO:0048010	vascular endothelial growth factor receptor signaling pathway
0.60	GO:0038084	vascular endothelial growth factor signaling pathway
0.58	GO:0071526	semaphorin-plexin signaling pathway
0.57	GO:0001525	angiogenesis
0.57	GO:0007411	axon guidance
0.55	GO:0009887	animal organ morphogenesis
0.43	GO:0006508	proteolysis
0.42	GO:0006898	receptor-mediated endocytosis
0.35	GO:0008104	protein localization

0.60	GO:0005021	vascular endothelial growth factor-activated receptor activity
0.58	GO:0017154	semaphorin receptor activity
0.57	GO:0019838	growth factor binding
0.45	GO:0005044	scavenger receptor activity
0.45	GO:0004175	endopeptidase activity
0.43	GO:0046872	metal ion binding
0.42	GO:0017171	serine hydrolase activity
0.40	GO:0008237	metallopeptidase activity
0.34	GO:0008061	chitin binding
0.34	GO:0019901	protein kinase binding

0.36	GO:0005576	extracellular region
0.34	GO:0097443	sorting endosome
0.34	GO:0005883	neurofilament
0.34	GO:0005903	brush border
0.34	GO:0005925	focal adhesion
0.34	GO:0005769	early endosome
0.34	GO:0030424	axon
0.33	GO:0005829	cytosol
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.33

GO:0004842

tr|H2Y3P6|H2Y3P6_CIOIN
Uncharacterized protein
Search

OCRL

0.90	Oculocerebrorenal syndrome of Lowe

0.81	GO:0046856	phosphatidylinositol dephosphorylation
0.61	GO:0007165	signal transduction
0.51	GO:0060271	cilium assembly
0.51	GO:0043009	chordate embryonic development
0.48	GO:0043547	positive regulation of GTPase activity
0.42	GO:0030317	flagellated sperm motility
0.42	GO:0070613	regulation of protein processing
0.42	GO:0071871	response to epinephrine
0.41	GO:0032402	melanosome transport
0.41	GO:0007283	spermatogenesis

0.80	GO:0052745	inositol phosphate phosphatase activity
0.58	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
0.52	GO:0048365	Rac GTPase binding
0.48	GO:0005096	GTPase activator activity
0.35	GO:0043813	phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity
0.35	GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity
0.32	GO:0046872	metal ion binding

0.51	GO:0001750	photoreceptor outer segment
0.50	GO:0005769	early endosome
0.49	GO:0005802	trans-Golgi network
0.49	GO:0030136	clathrin-coated vesicle
0.42	GO:0005634	nucleus
0.40	GO:0005886	plasma membrane
0.39	GO:0005829	cytosol
0.39	GO:0030670	phagocytic vesicle membrane
0.37	GO:0010008	endosome membrane
0.37	GO:0005905	clathrin-coated pit

0.80	EC:3.1.3	GO:0052745
0.58	KEGG:R04404	GO:0004439

tr|H2Y3P7|H2Y3P7_CIOIN
Uncharacterized protein
Search

tr|H2Y3P8|H2Y3P8_CIOIN
Uncharacterized protein
Search

tr|H2Y3P9|H2Y3P9_CIOIN
Uncharacterized protein
Search

tr|H2Y3Q0|H2Y3Q0_CIOIN
Uncharacterized protein
Search

tr|H2Y3Q1|H2Y3Q1_CIOIN
Uncharacterized protein
Search

0.51	carnitine O-palmitoyltransferase 1, liver isoform

0.36	GO:0019254	carnitine metabolic process, CoA-linked
0.35	GO:0007626	locomotory behavior
0.34	GO:0045733	acetate catabolic process
0.34	GO:0006853	carnitine shuttle
0.34	GO:0006468	protein phosphorylation
0.33	GO:0015976	carbon utilization
0.33	GO:0009062	fatty acid catabolic process

0.63	GO:0016746	transferase activity, transferring acyl groups
0.34	GO:0005102	receptor binding
0.34	GO:0016301	kinase activity
0.34	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.33	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.35	GO:0005777	peroxisome
0.34	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.63

EC:2.3

GO:0016746

tr|H2Y3Q2|H2Y3Q2_CIOIN
Uncharacterized protein
Search

tr|H2Y3Q3|H2Y3Q3_CIOIN
Uncharacterized protein
Search

tr|H2Y3Q4|H2Y3Q4_CIOIN
Uncharacterized protein
Search

tr|H2Y3Q5|H2Y3Q5_CIOIN
Uncharacterized protein
Search

tr|H2Y3Q6|H2Y3Q6_CIOIN
Aminomethyltransferase
Search

AMT

0.55	Aminomethyltransferase, mitochondrial

0.75	GO:0006546	glycine catabolic process
0.62	GO:0032259	methylation

0.79	GO:0004047	aminomethyltransferase activity
0.67	GO:0008483	transaminase activity
0.35	GO:0031405	lipoic acid binding
0.32	GO:0003676	nucleic acid binding

0.59	GO:0005739	mitochondrion
0.45	GO:0005654	nucleoplasm
0.35	GO:0005960	glycine cleavage complex
0.33	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.79

EC:2.1.2.10

GO:0004047

tr|H2Y3Q7|H2Y3Q7_CIOIN
Uncharacterized protein
Search

tr|H2Y3Q8|H2Y3Q8_CIOIN
Uncharacterized protein
Search

0.61

GO:0007165

signal transduction

0.81

GO:0032947

protein complex scaffold activity

tr|H2Y3Q9|H2Y3Q9_CIOIN
Uncharacterized protein
Search

0.12	mucosa-associated lymphoid tissue lymphoma translocation protein 1-like

0.66	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.61	GO:0006508	proteolysis

0.75

GO:0004197

cysteine-type endopeptidase activity

0.75

EC:3.4.22

GO:0004197

tr|H2Y3R0|H2Y3R0_CIOIN
Uncharacterized protein
Search

tr|H2Y3R1|H2Y3R1_CIOIN
Uncharacterized protein
Search

tr|H2Y3R2|H2Y3R2_CIOIN
Uncharacterized protein
Search

PGGHG

0.75	Protein-glucosylgalactosylhydroxylysine glucosidase

0.60

GO:0005975

carbohydrate metabolic process

0.56	GO:0047402	protein-glucosylgalactosylhydroxylysine glucosidase activity
0.35	GO:0030246	carbohydrate binding
0.31	GO:0030554	adenyl nucleotide binding
0.31	GO:0097367	carbohydrate derivative binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.45	GO:0005618	cell wall
0.45	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.56

EC:3.2.1.107

GO:0047402

tr|H2Y3R4|H2Y3R4_CIOIN
Uncharacterized protein
Search

tr|H2Y3R5|H2Y3R5_CIOIN
Uncharacterized protein
Search

tr|H2Y3R6|H2Y3R6_CIOIN
Uncharacterized protein
Search

0.55	GO:0045892	negative regulation of transcription, DNA-templated
0.52	GO:0035556	intracellular signal transduction
0.50	GO:0006897	endocytosis
0.42	GO:0035023	regulation of Rho protein signal transduction
0.41	GO:0065009	regulation of molecular function

0.46	GO:0046872	metal ion binding
0.45	GO:0003677	DNA binding
0.42	GO:0005089	Rho guanyl-nucleotide exchange factor activity

0.61	GO:0016607	nuclear speck
0.40	GO:0031410	cytoplasmic vesicle
0.39	GO:0005856	cytoskeleton
0.38	GO:0012506	vesicle membrane
0.37	GO:0098805	whole membrane
0.37	GO:0098588	bounding membrane of organelle
0.36	GO:0005886	plasma membrane

tr|H2Y3R7|H2Y3R7_CIOIN
Uncharacterized protein
Search

0.45

GO:0005975

carbohydrate metabolic process

0.30

GO:0003824

catalytic activity

0.38	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

tr|H2Y3R8|H2Y3R8_CIOIN
Uncharacterized protein
Search

0.10

Ankyrin-2

0.59	GO:0007165	signal transduction
0.44	GO:0042157	lipoprotein metabolic process
0.44	GO:0006869	lipid transport
0.33	GO:0022900	electron transport chain

0.43	GO:0008289	lipid binding
0.37	GO:0030507	spectrin binding
0.36	GO:0102568	phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
0.36	GO:0102567	phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
0.36	GO:0004623	phospholipase A2 activity
0.34	GO:0016651	oxidoreductase activity, acting on NAD(P)H

0.41	GO:0005576	extracellular region
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.36

EC:3.1.1.4

GO:0004623

tr|H2Y3R9|H2Y3R9_CIOIN
Uncharacterized protein
Search

0.58	GO:0006508	proteolysis
0.38	GO:0006626	protein targeting to mitochondrion
0.38	GO:0051604	protein maturation
0.35	GO:0000747	conjugation with cellular fusion
0.35	GO:0044267	cellular protein metabolic process

0.67	GO:0004222	metalloendopeptidase activity
0.54	GO:0046872	metal ion binding

0.36	GO:0031966	mitochondrial membrane
0.36	GO:0019866	organelle inner membrane
0.34	GO:0019898	extrinsic component of membrane
0.30	GO:0016021	integral component of membrane

0.67

GO:0004222

tr|H2Y3S0|H2Y3S0_CIOIN
Uncharacterized protein
Search

tr|H2Y3S1|H2Y3S1_CIOIN
Uncharacterized protein
Search

ASPA

0.85	N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming)

0.39	GO:0048714	positive regulation of oligodendrocyte differentiation
0.39	GO:0022010	central nervous system myelination
0.35	GO:0006533	aspartate catabolic process
0.34	GO:0006083	acetate metabolic process
0.34	GO:0006805	xenobiotic metabolic process
0.33	GO:0016032	viral process
0.33	GO:0008652	cellular amino acid biosynthetic process
0.32	GO:0055114	oxidation-reduction process

0.68	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
0.61	GO:0016788	hydrolase activity, acting on ester bonds
0.52	GO:0046872	metal ion binding
0.52	GO:0042802	identical protein binding
0.33	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

0.46	GO:0005829	cytosol
0.45	GO:0016324	apical plasma membrane
0.38	GO:0070062	extracellular exosome
0.37	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.68

EC:3.5.1

GO:0016811

tr|H2Y3S2|H2Y3S2_CIOIN
Uncharacterized protein
Search

tr|H2Y3S3|H2Y3S3_CIOIN
Uncharacterized protein
Search

0.57	Macrophage migration inhibitory factor

0.72

GO:0050178

phenylpyruvate tautomerase activity

0.52	GO:0009507	chloroplast
0.30	GO:0044425	membrane part

0.72

EC:5.3.2.1

GO:0050178

tr|H2Y3S4|H2Y3S4_CIOIN
Uncharacterized protein
Search

tr|H2Y3S5|H2Y3S5_CIOIN
Uncharacterized protein
Search

tr|H2Y3S6|H2Y3S6_CIOIN
Uncharacterized protein
Search

tr|H2Y3S7|H2Y3S7_CIOIN
Uncharacterized protein
Search

0.81	GO:0006368	transcription elongation from RNA polymerase II promoter
0.77	GO:0042795	snRNA transcription by RNA polymerase II
0.53	GO:0006414	translational elongation
0.51	GO:0001570	vasculogenesis
0.44	GO:0042796	snRNA transcription by RNA polymerase III
0.43	GO:0045945	positive regulation of transcription by RNA polymerase III
0.42	GO:0001701	in utero embryonic development
0.42	GO:0010923	negative regulation of phosphatase activity
0.42	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter
0.33	GO:0006595	polyamine metabolic process

0.54	GO:0003746	translation elongation factor activity
0.42	GO:0019902	phosphatase binding
0.34	GO:0008073	ornithine decarboxylase inhibitor activity

0.79	GO:0008023	transcription elongation factor complex
0.44	GO:0035363	histone locus body
0.43	GO:0015030	Cajal body
0.43	GO:0035327	transcriptionally active chromatin
0.41	GO:0016607	nuclear speck
0.33	GO:0005829	cytosol

tr|H2Y3S8|H2Y3S8_CIOIN
Uncharacterized protein
Search

tr|H2Y3S9|H2Y3S9_CIOIN
Uncharacterized protein
Search

tr|H2Y3T0|H2Y3T0_CIOIN
Uncharacterized protein
Search

tr|H2Y3T1|H2Y3T1_CIOIN
Uncharacterized protein
Search

tr|H2Y3T2|H2Y3T2_CIOIN
Uncharacterized protein
Search

tr|H2Y3T3|H2Y3T3_CIOIN
Uncharacterized protein
Search

tr|H2Y3T4|H2Y3T4_CIOIN
Uncharacterized protein
Search

PDCD10

0.96	programmed cell death protein 10

0.86	GO:0036481	intrinsic apoptotic signaling pathway in response to hydrogen peroxide
0.86	GO:0090168	Golgi reassembly
0.86	GO:1903588	negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis
0.85	GO:0051683	establishment of Golgi localization
0.85	GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis
0.84	GO:0090505	epiboly involved in wound healing
0.82	GO:0045747	positive regulation of Notch signaling pathway
0.82	GO:0033138	positive regulation of peptidyl-serine phosphorylation
0.81	GO:1990830	cellular response to leukemia inhibitory factor
0.80	GO:0032874	positive regulation of stress-activated MAPK cascade

0.82	GO:0047485	protein N-terminus binding
0.75	GO:0019901	protein kinase binding
0.72	GO:0042803	protein homodimerization activity

0.71	GO:0005794	Golgi apparatus
0.66	GO:0005829	cytosol
0.49	GO:0098588	bounding membrane of organelle
0.47	GO:0031984	organelle subcompartment
0.42	GO:0070062	extracellular exosome
0.42	GO:0005886	plasma membrane

tr|H2Y3T5|H2Y3T5_CIOIN
Uncharacterized protein
Search

tr|H2Y3T6|H2Y3T6_CIOIN
Uncharacterized protein
Search

RRAS2

0.65	Ras oncogene

0.61	GO:0007165	signal transduction
0.37	GO:1901214	regulation of neuron death
0.37	GO:0030335	positive regulation of cell migration
0.34	GO:0008284	positive regulation of cell proliferation

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032553	ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0004767	sphingomyelin phosphodiesterase activity
0.33	GO:0005515	protein binding

0.33	GO:0005886	plasma membrane
0.33	GO:0005622	intracellular
0.32	GO:0043227	membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.34	EC:3.1.4.12	GO:0004767
0.34	KEGG:R02541	GO:0004767

tr|H2Y3T7|H2Y3T7_CIOIN
Uncharacterized protein
Search

tr|H2Y3T8|H2Y3T8_CIOIN
Uncharacterized protein
Search

tr|H2Y3T9|H2Y3T9_CIOIN
Uncharacterized protein
Search

tr|H2Y3U0|H2Y3U0_CIOIN
Uncharacterized protein
Search

tr|H2Y3U1|H2Y3U1_CIOIN
Uncharacterized protein
Search

tr|H2Y3U2|H2Y3U2_CIOIN
Uncharacterized protein
Search

NATD1

0.97	N-acetyltransferase domain containing 1

0.49

GO:0005515

protein binding

tr|H2Y3U3|H2Y3U3_CIOIN
Uncharacterized protein
Search

tr|H2Y3U4|H2Y3U4_CIOIN
Uncharacterized protein
Search

tr|H2Y3U5|H2Y3U5_CIOIN
Uncharacterized protein
Search

tr|H2Y3U6|H2Y3U6_CIOIN
Uncharacterized protein
Search

0.62	Dynein, axonemal, heavy chain 7

0.74	GO:0007018	microtubule-based movement
0.55	GO:0036159	inner dynein arm assembly
0.43	GO:0071910	determination of liver left/right asymmetry
0.43	GO:0007605	sensory perception of sound
0.42	GO:0006072	glycerol-3-phosphate metabolic process
0.36	GO:0055114	oxidation-reduction process
0.35	GO:0060285	cilium-dependent cell motility
0.35	GO:0061817	endoplasmic reticulum-plasma membrane tethering
0.34	GO:0006869	lipid transport
0.33	GO:0006468	protein phosphorylation

0.75	GO:0003777	microtubule motor activity
0.59	GO:0005509	calcium ion binding
0.52	GO:0032559	adenyl ribonucleotide binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0045503	dynein light chain binding
0.49	GO:0051959	dynein light intermediate chain binding
0.49	GO:0045505	dynein intermediate chain binding
0.44	GO:0016887	ATPase activity
0.43	GO:0004368	glycerol-3-phosphate dehydrogenase activity

0.79	GO:0030286	dynein complex
0.55	GO:0044447	axoneme part
0.45	GO:0005829	cytosol
0.42	GO:0009331	glycerol-3-phosphate dehydrogenase complex
0.35	GO:0005874	microtubule
0.30	GO:0031224	intrinsic component of membrane

0.44

GO:0016887

tr|H2Y3U7|H2Y3U7_CIOIN
Uncharacterized protein
Search

0.69	GO:0006457	protein folding
0.51	GO:1904869	regulation of protein localization to Cajal body
0.50	GO:1904851	positive regulation of establishment of protein localization to telomere
0.50	GO:1904874	positive regulation of telomerase RNA localization to Cajal body
0.49	GO:0032212	positive regulation of telomere maintenance via telomerase
0.49	GO:0046931	pore complex assembly
0.49	GO:0007339	binding of sperm to zona pellucida
0.48	GO:1900182	positive regulation of protein localization to nucleus
0.47	GO:0050821	protein stabilization
0.47	GO:1901998	toxin transport

0.71	GO:0051082	unfolded protein binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0045296	cadherin binding
0.47	GO:0044183	protein binding involved in protein folding
0.33	GO:0042623	ATPase activity, coupled

0.53	GO:0005832	chaperonin-containing T-complex
0.50	GO:0002199	zona pellucida receptor complex
0.47	GO:0044297	cell body
0.47	GO:0045111	intermediate filament cytoskeleton
0.46	GO:0005815	microtubule organizing center
0.44	GO:0005874	microtubule
0.44	GO:0005654	nucleoplasm
0.37	GO:0005929	cilium
0.35	GO:0070062	extracellular exosome
0.34	GO:1904813	ficolin-1-rich granule lumen

tr|H2Y3U8|H2Y3U8_CIOIN
Uncharacterized protein
Search

tr|H2Y3U9|H2Y3U9_CIOIN
Uncharacterized protein
Search

0.42

GO:0055114

oxidation-reduction process

0.50	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.47	GO:0020037	heme binding
0.47	GO:0005506	iron ion binding

0.30

GO:0031224

intrinsic component of membrane

0.50

GO:0016705

tr|H2Y3V0|H2Y3V0_CIOIN
Uncharacterized protein
Search

0.43	GO:0031124	mRNA 3'-end processing
0.40	GO:0007186	G-protein coupled receptor signaling pathway
0.40	GO:0018298	protein-chromophore linkage
0.36	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
0.36	GO:0032469	endoplasmic reticulum calcium ion homeostasis
0.36	GO:0030163	protein catabolic process
0.36	GO:0003006	developmental process involved in reproduction
0.36	GO:0009607	response to biotic stimulus
0.36	GO:0006508	proteolysis
0.35	GO:0006334	nucleosome assembly

0.51	GO:0005544	calcium-dependent phospholipid binding
0.46	GO:0005509	calcium ion binding
0.41	GO:0009881	photoreceptor activity
0.40	GO:0003723	RNA binding
0.40	GO:0004930	G-protein coupled receptor activity
0.37	GO:0030246	carbohydrate binding
0.36	GO:0050699	WW domain binding
0.36	GO:0044325	ion channel binding
0.36	GO:0008233	peptidase activity
0.35	GO:0003713	transcription coactivator activity

0.37	GO:0043231	intracellular membrane-bounded organelle
0.36	GO:0012505	endomembrane system
0.35	GO:0120114	Sm-like protein family complex
0.35	GO:0000786	nucleosome
0.35	GO:0005886	plasma membrane
0.34	GO:0044444	cytoplasmic part
0.34	GO:0019867	outer membrane
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016021	integral component of membrane

0.36

EC:3.4

GO:0008233

tr|H2Y3V1|H2Y3V1_CIOIN
Uncharacterized protein
Search

0.45	GO:0048082	regulation of adult chitin-containing cuticle pigmentation
0.45	GO:0007275	multicellular organism development
0.43	GO:0032879	regulation of localization
0.42	GO:0007165	signal transduction
0.41	GO:0006898	receptor-mediated endocytosis
0.40	GO:0034220	ion transmembrane transport
0.40	GO:0042395	ecdysis, collagen and cuticulin-based cuticle
0.39	GO:0006508	proteolysis
0.39	GO:0040012	regulation of locomotion
0.39	GO:0040018	positive regulation of multicellular organism growth

0.64	GO:0005509	calcium ion binding
0.46	GO:0005230	extracellular ligand-gated ion channel activity
0.45	GO:0004872	receptor activity
0.42	GO:0004871	signal transducer activity
0.42	GO:0004252	serine-type endopeptidase activity
0.39	GO:0015248	sterol transporter activity
0.35	GO:0034437	glycoprotein transporter activity
0.35	GO:0034189	very-low-density lipoprotein particle binding
0.35	GO:0034185	apolipoprotein binding
0.35	GO:0048306	calcium-dependent protein binding

0.45	GO:0016324	apical plasma membrane
0.39	GO:0031410	cytoplasmic vesicle
0.38	GO:0012505	endomembrane system
0.35	GO:0097223	sperm part
0.35	GO:0005829	cytosol
0.35	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0043235	receptor complex
0.34	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane

0.42

GO:0004252

tr|I6L212|I6L212_CIOIN
S-methyl-5'-thioadenosine phosphorylase
Search

MTAP

0.66	S-methyl-5'-thioadenosine phosphorylase

0.71	GO:0006166	purine ribonucleoside salvage
0.68	GO:0019509	L-methionine salvage from methylthioadenosine
0.40	GO:0032259	methylation
0.37	GO:0070638	pyridine nucleoside catabolic process
0.37	GO:0046495	nicotinamide riboside metabolic process
0.35	GO:0035722	interleukin-12-mediated signaling pathway
0.35	GO:0033574	response to testosterone

0.81	GO:0017061	S-methyl-5-thioadenosine phosphorylase activity
0.34	GO:0004645	phosphorylase activity
0.33	GO:0005515	protein binding

0.56	GO:0005634	nucleus
0.46	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome

0.81

EC:2.4.2.28

GO:0017061

tr|I6L237|I6L237_CIOIN
ATP-dependent (S)-NAD(P)H-hydrate dehydratase
Search

0.74	ATP-dependent (S)-NAD(P)H-hydrate dehydratase

0.64	GO:0019362	pyridine nucleotide metabolic process
0.40	GO:0016310	phosphorylation
0.33	GO:0072525	pyridine-containing compound biosynthetic process
0.33	GO:0009108	coenzyme biosynthetic process
0.33	GO:0009165	nucleotide biosynthetic process

0.82	GO:0047453	ATP-dependent NAD(P)H-hydrate dehydratase activity
0.79	GO:0052855	ADP-dependent NAD(P)H-hydrate dehydratase activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0052857	NADPHX epimerase activity
0.44	GO:0052856	NADHX epimerase activity
0.41	GO:0016301	kinase activity
0.33	GO:0005515	protein binding

0.44	GO:0005739	mitochondrion
0.41	GO:0005829	cytosol
0.40	GO:0009507	chloroplast
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.82	EC:4.2.1.93	GO:0047453
0.82	KEGG:R00129	GO:0047453

tr|I6L2C8|I6L2C8_CIOIN
1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase
Search

0.75	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase

0.76	GO:0019509	L-methionine salvage from methylthioadenosine
0.52	GO:0055114	oxidation-reduction process
0.42	GO:2000243	positive regulation of reproductive process
0.34	GO:0051302	regulation of cell division
0.33	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.32	GO:0006091	generation of precursor metabolites and energy

0.82	GO:0010309	acireductone dioxygenase [iron(II)-requiring] activity
0.58	GO:0005506	iron ion binding
0.35	GO:0010308	acireductone dioxygenase (Ni2+-requiring) activity
0.33	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.33	GO:0009055	electron transfer activity
0.32	GO:0003676	nucleic acid binding

0.60	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.39	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.82	EC:1.13.11.54	GO:0010309
0.82	KEGG:R07364	GO:0010309

tr|I6L7H7|I6L7H7_CIOIN
tRNA (guanine(37)-N1)-methyltransferase
Search

TRMT5

0.71	tRNA (Guanine-N(1)-)-methyltransferase (Fragment)

0.73	GO:0030488	tRNA methylation
0.56	GO:0070900	mitochondrial tRNA modification
0.33	GO:0006433	prolyl-tRNA aminoacylation

0.79	GO:0009019	tRNA (guanine-N1-)-methyltransferase activity
0.33	GO:0004827	proline-tRNA ligase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.74	GO:0005759	mitochondrial matrix
0.61	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.79

GO:0009019

tr|K9J6P3|K9J6P3_CIOIN
Uncharacterized protein
Search

0.46	Chymotrypsin like

0.61	GO:0006508	proteolysis
0.39	GO:0007596	blood coagulation
0.35	GO:0006898	receptor-mediated endocytosis
0.35	GO:0006958	complement activation, classical pathway
0.34	GO:0032324	molybdopterin cofactor biosynthetic process
0.33	GO:0019835	cytolysis
0.33	GO:0008219	cell death
0.33	GO:0036211	protein modification process

0.69	GO:0004252	serine-type endopeptidase activity
0.37	GO:0005509	calcium ion binding
0.36	GO:0005044	scavenger receptor activity
0.35	GO:0008641	ubiquitin-like modifier activating enzyme activity
0.33	GO:0016758	transferase activity, transferring hexosyl groups

0.36	GO:0005615	extracellular space
0.35	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.69

GO:0004252

tr|K9J6P5|K9J6P5_CIOIN
Cytosolic Fe-S cluster assembly factor NUBP2 homolog
Search

NUBP2

0.92	Cytosolic Fe-S cluster assembly factor NUBP2

0.71	GO:0016226	iron-sulfur cluster assembly
0.36	GO:0002098	tRNA wobble uridine modification
0.35	GO:0030030	cell projection organization
0.33	GO:0030001	metal ion transport
0.33	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.32	GO:0055085	transmembrane transport

0.65	GO:0051539	4 iron, 4 sulfur cluster binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0046872	metal ion binding
0.34	GO:0016887	ATPase activity
0.33	GO:0046873	metal ion transmembrane transporter activity
0.33	GO:0004519	endonuclease activity
0.33	GO:0005515	protein binding

0.49	GO:0005815	microtubule organizing center
0.46	GO:0005737	cytoplasm
0.46	GO:0000922	spindle pole
0.43	GO:0005634	nucleus
0.35	GO:0005929	cilium
0.35	GO:1904949	ATPase complex
0.34	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0016887

tr|K9J6P6|K9J6P6_CIOIN
Uncharacterized protein
Search

0.52

GO:0006508

proteolysis

0.58	GO:0070001	aspartic-type peptidase activity
0.55	GO:0004175	endopeptidase activity
0.48	GO:0030554	adenyl nucleotide binding
0.47	GO:0097367	carbohydrate derivative binding
0.47	GO:0008144	drug binding
0.47	GO:0035639	purine ribonucleoside triphosphate binding

tr|K9J6P7|K9J6P7_CIOIN
Uncharacterized protein
Search

0.63	kelch-like protein diablo

tr|K9J6P8|K9J6P8_CIOIN
Uncharacterized protein
Search

tr|L7N0Q2|L7N0Q2_CIOIN
Uncharacterized protein
Search

tr|L7N0Q3|L7N0Q3_CIOIN
Uncharacterized protein
Search

tr|L7N0Q4|L7N0Q4_CIOIN
Uncharacterized protein
Search

0.48	GO:0007186	G-protein coupled receptor signaling pathway
0.42	GO:0045959	negative regulation of complement activation, classical pathway
0.39	GO:0045732	positive regulation of protein catabolic process
0.38	GO:0006030	chitin metabolic process
0.35	GO:0006508	proteolysis

0.62	GO:0030246	carbohydrate binding
0.49	GO:0004930	G-protein coupled receptor activity
0.38	GO:0008061	chitin binding
0.37	GO:0004252	serine-type endopeptidase activity
0.36	GO:0005509	calcium ion binding

0.46	GO:0005581	collagen trimer
0.39	GO:0005576	extracellular region
0.36	GO:0044217	other organism part
0.30	GO:0016021	integral component of membrane

0.37

GO:0004252

tr|L7N0Q5|L7N0Q5_CIOIN
Uncharacterized protein
Search

tr|L7N0Q6|L7N0Q6_CIOIN
Uncharacterized protein
Search

0.56	Alpha-(1,6)-fucosyltransferase

0.76	GO:0036071	N-glycan fucosylation
0.75	GO:0033578	protein glycosylation in Golgi
0.38	GO:0006487	protein N-linked glycosylation
0.38	GO:0006004	fucose metabolic process

0.76	GO:0046921	alpha-(1->6)-fucosyltransferase activity
0.69	GO:0140103	catalytic activity, acting on a glycoprotein
0.33	GO:0008017	microtubule binding

0.67	GO:0032580	Golgi cisterna membrane
0.30	GO:0031224	intrinsic component of membrane

0.76

GO:0046921

tr|L7N0Q7|L7N0Q7_CIOIN
Uncharacterized protein
Search

tr|L7N0Q8|L7N0Q8_CIOIN
Uncharacterized protein
Search

tr|L7N0Q9|L7N0Q9_CIOIN
Uncharacterized protein
Search

0.75	RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

0.58	GO:0007389	pattern specification process
0.54	GO:0036066	protein O-linked fucosylation
0.52	GO:0045747	positive regulation of Notch signaling pathway
0.52	GO:0032092	positive regulation of protein binding
0.48	GO:0002315	marginal zone B cell differentiation
0.35	GO:0007399	nervous system development
0.34	GO:0045746	negative regulation of Notch signaling pathway
0.34	GO:0043461	proton-transporting ATP synthase complex assembly
0.33	GO:0055114	oxidation-reduction process
0.32	GO:0006508	proteolysis

0.66	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity
0.41	GO:0046872	metal ion binding
0.33	GO:0016491	oxidoreductase activity
0.32	GO:0005515	protein binding
0.32	GO:0004222	metalloendopeptidase activity

0.60	GO:0030173	integral component of Golgi membrane
0.34	GO:0005615	extracellular space
0.34	GO:1903561	extracellular vesicle

0.66

EC:2.4.1.222

GO:0033829

tr|L7N0R0|L7N0R0_CIOIN
Uncharacterized protein
Search

0.55	GO:2001141	regulation of RNA biosynthetic process
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.51	GO:0016310	phosphorylation
0.41	GO:0030336	negative regulation of cell migration
0.40	GO:0016570	histone modification
0.39	GO:0051253	negative regulation of RNA metabolic process
0.39	GO:0010558	negative regulation of macromolecule biosynthetic process
0.39	GO:0031327	negative regulation of cellular biosynthetic process
0.34	GO:0097190	apoptotic signaling pathway

0.53	GO:0016301	kinase activity
0.51	GO:0046872	metal ion binding
0.46	GO:0042393	histone binding
0.43	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.43	GO:0003712	transcription cofactor activity
0.43	GO:0003682	chromatin binding
0.42	GO:0140033	acetylation-dependent protein binding
0.42	GO:0140034	methylation-dependent protein binding
0.34	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.34	GO:0070491	repressing transcription factor binding

0.40

GO:0005634

nucleus

tr|L7N0R1|L7N0R1_CIOIN
Uncharacterized protein
Search

tr|L7N0R2|L7N0R2_CIOIN
Uncharacterized protein
Search

0.37	Zinc finger domain-containing protein (Fragment)

0.48	GO:1903506	regulation of nucleic acid-templated transcription
0.48	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.48	GO:0010468	regulation of gene expression
0.41	GO:1902679	negative regulation of RNA biosynthetic process
0.39	GO:0006351	transcription, DNA-templated
0.36	GO:1902680	positive regulation of RNA biosynthetic process
0.33	GO:0070285	pigment cell development
0.33	GO:0001755	neural crest cell migration
0.32	GO:1902600	hydrogen ion transmembrane transport
0.32	GO:0022900	electron transport chain

0.51	GO:0003676	nucleic acid binding
0.46	GO:0046872	metal ion binding
0.42	GO:0003700	DNA binding transcription factor activity
0.34	GO:0005515	protein binding
0.33	GO:0015002	heme-copper terminal oxidase activity
0.33	GO:0016675	oxidoreductase activity, acting on a heme group of donors
0.32	GO:0015078	hydrogen ion transmembrane transporter activity
0.32	GO:0009055	electron transfer activity

0.42	GO:0005634	nucleus
0.33	GO:0005746	mitochondrial respiratory chain
0.33	GO:0043233	organelle lumen
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:1.9

GO:0016675

tr|L7N0R3|L7N0R3_CIOIN
Uncharacterized protein
Search

tr|L7N0R4|L7N0R4_CIOIN
Uncharacterized protein
Search

0.31	3-hydroxybutyrate dehydrogenase type 2

0.52	GO:0055114	oxidation-reduction process
0.35	GO:0006633	fatty acid biosynthetic process

0.53	GO:0016491	oxidoreductase activity
0.41	GO:0004312	fatty acid synthase activity
0.35	GO:0051287	NAD binding

0.53

EC:1

GO:0016491

tr|L7N0R5|L7N0R5_CIOIN
Uncharacterized protein
Search

0.32	Short chain enoyl-CoA hydratase

0.37	GO:0071456	cellular response to hypoxia
0.33	GO:0007017	microtubule-based process
0.33	GO:0035556	intracellular signal transduction
0.30	GO:0008152	metabolic process

0.48	GO:0004300	enoyl-CoA hydratase activity
0.41	GO:0016853	isomerase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003676	nucleic acid binding

0.33	GO:0030286	dynein complex
0.30	GO:0031224	intrinsic component of membrane

0.48

EC:4.2.1.17

GO:0004300

tr|L7N0R6|L7N0R6_CIOIN
Uncharacterized protein
Search

0.75	Sodium-dependent Vitamin C transporter 2

0.55	GO:0055085	transmembrane transport
0.43	GO:0015882	L-ascorbic acid transport
0.33	GO:0035335	peptidyl-tyrosine dephosphorylation
0.32	GO:0055114	oxidation-reduction process

0.57	GO:0022857	transmembrane transporter activity
0.33	GO:0004725	protein tyrosine phosphatase activity
0.33	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

0.30

GO:0016021

integral component of membrane

0.33

EC:3.1.3.48

GO:0004725

tr|L7N0R7|L7N0R7_CIOIN
Uncharacterized protein
Search

0.30

GO:0044425

membrane part

tr|L7N0R8|L7N0R8_CIOIN
Uncharacterized protein
Search

ABCG2

0.87	ATP binding cassette subfamily G member 2 (Junior blood group)

0.49	GO:0033344	cholesterol efflux
0.48	GO:0055085	transmembrane transport
0.48	GO:0046415	urate metabolic process
0.43	GO:0015893	drug transport
0.35	GO:0097744	urate salt excretion
0.35	GO:0042908	xenobiotic transport
0.35	GO:1904612	response to 2,3,7,8-tetrachlorodibenzodioxine
0.35	GO:0019389	glucuronoside metabolic process
0.35	GO:1904479	negative regulation of intestinal absorption
0.35	GO:0060136	embryonic process involved in female pregnancy

0.61	GO:0016887	ATPase activity
0.56	GO:0015399	primary active transmembrane transporter activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0017127	cholesterol transporter activity
0.45	GO:0042803	protein homodimerization activity
0.36	GO:0015238	drug transmembrane transporter activity
0.35	GO:0042910	xenobiotic transmembrane transporter activity
0.34	GO:0015232	heme transporter activity

0.47	GO:0016324	apical plasma membrane
0.46	GO:0043235	receptor complex
0.41	GO:0005634	nucleus
0.36	GO:0043190	ATP-binding cassette (ABC) transporter complex
0.35	GO:0031966	mitochondrial membrane

0.61

GO:0016887

tr|L7N0R9|L7N0R9_CIOIN
Uncharacterized protein
Search

0.51	Lethal neighbour of tid protein (Fragment)

0.66	GO:0097502	mannosylation
0.62	GO:0006486	protein glycosylation
0.34	GO:0006488	dolichol-linked oligosaccharide biosynthetic process

0.73	GO:0052925	dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity
0.33	GO:0005515	protein binding

0.70	GO:0005783	endoplasmic reticulum
0.60	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.58	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.73	EC:2.4.1.258	GO:0052925
0.73	KEGG:R06258	GO:0052925

tr|L7N0S0|L7N0S0_CIOIN
Uncharacterized protein
Search

0.53	GO:0055114	oxidation-reduction process
0.49	GO:0036378	calcitriol biosynthetic process from calciol
0.37	GO:0010164	response to cesium ion
0.36	GO:0016098	monoterpenoid metabolic process
0.36	GO:2000863	positive regulation of estrogen secretion
0.36	GO:0010212	response to ionizing radiation
0.35	GO:0001998	angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure
0.35	GO:0097254	renal tubular secretion
0.35	GO:0044550	secondary metabolite biosynthetic process
0.35	GO:0019369	arachidonic acid metabolic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.66	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.50	GO:0030343	vitamin D3 25-hydroxylase activity
0.34	GO:0019899	enzyme binding
0.33	GO:0051213	dioxygenase activity
0.32	GO:0010181	FMN binding
0.32	GO:0003958	NADPH-hemoprotein reductase activity
0.31	GO:0008168	methyltransferase activity

0.35	GO:0005783	endoplasmic reticulum
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0031984	organelle subcompartment
0.33	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

0.68

GO:0016705

tr|L7N0S1|L7N0S1_CIOIN
Uncharacterized protein
Search

tr|L7N0S2|L7N0S2_CIOIN
Uncharacterized protein
Search

0.52	Interferon-related developmental regulator-related (inferred by orthology to a S. mansoni protein)

0.76	GO:0048671	negative regulation of collateral sprouting
0.74	GO:0043403	skeletal muscle tissue regeneration
0.74	GO:0030517	negative regulation of axon extension
0.68	GO:0014706	striated muscle tissue development
0.68	GO:0042692	muscle cell differentiation
0.44	GO:0007018	microtubule-based movement
0.41	GO:0009651	response to salt stress

0.44	GO:0003777	microtubule motor activity
0.38	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding

0.54	GO:0005634	nucleus
0.46	GO:0005737	cytoplasm
0.45	GO:0030286	dynein complex
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0S3|L7N0S3_CIOIN
Uncharacterized protein
Search

WDR3

0.94	WD repeat-containing protein 3

0.66	GO:0030490	maturation of SSU-rRNA
0.50	GO:0000479	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.49	GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.49	GO:0000967	rRNA 5'-end processing
0.38	GO:0051209	release of sequestered calcium ion into cytosol
0.35	GO:0006468	protein phosphorylation
0.34	GO:0032259	methylation
0.33	GO:0055114	oxidation-reduction process

0.70	GO:0030515	snoRNA binding
0.38	GO:0016905	myosin heavy chain kinase activity
0.38	GO:0005219	ryanodine-sensitive calcium-release channel activity
0.37	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.34	GO:0008168	methyltransferase activity

0.73	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome
0.70	GO:0031965	nuclear membrane
0.67	GO:0032040	small-subunit processome
0.36	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.38

EC:2.7.11.7

GO:0016905

tr|L7N0S4|L7N0S4_CIOIN
Uncharacterized protein
Search

0.20	Thymidylate synthase

0.78	GO:0006231	dTMP biosynthetic process
0.63	GO:0032259	methylation
0.59	GO:0046654	tetrahydrofolate biosynthetic process
0.58	GO:0006730	one-carbon metabolic process
0.45	GO:0055114	oxidation-reduction process
0.44	GO:0006235	dTTP biosynthetic process
0.38	GO:0060041	retina development in camera-type eye
0.36	GO:0009256	10-formyltetrahydrofolate metabolic process
0.35	GO:0046683	response to organophosphorus
0.34	GO:0043650	dicarboxylic acid biosynthetic process

0.79	GO:0004799	thymidylate synthase activity
0.62	GO:0004146	dihydrofolate reductase activity
0.35	GO:1990825	sequence-specific mRNA binding
0.35	GO:0000900	translation repressor activity, nucleic acid binding
0.33	GO:0004386	helicase activity
0.33	GO:0008233	peptidase activity

0.36	GO:0005737	cytoplasm
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0019866	organelle inner membrane
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.79	EC:2.1.1.45	GO:0004799
0.79	KEGG:R02101	GO:0004799

tr|L7N0S5|L7N0S5_CIOIN
Uncharacterized protein
Search

0.97	glutathione S-transferase omega-1-like

0.30

GO:0008152

metabolic process

0.76

GO:0004364

glutathione transferase activity

0.47

GO:0005737

cytoplasm

0.76

EC:2.5.1.18

GO:0004364

tr|L7N0S6|L7N0S6_CIOIN
Signal peptidase complex catalytic subunit SEC11
Search

SEC11C

0.71	Signal peptidase complex catalytic subunit SEC11

0.80	GO:0006465	signal peptide processing
0.35	GO:0006351	transcription, DNA-templated
0.34	GO:0018108	peptidyl-tyrosine phosphorylation

0.67	GO:0017171	serine hydrolase activity
0.62	GO:0070011	peptidase activity, acting on L-amino acid peptides
0.37	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.34	GO:0004713	protein tyrosine kinase activity
0.34	GO:0003676	nucleic acid binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.82	GO:0005787	signal peptidase complex
0.36	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

0.37

EC:2.7.7.6

GO:0003899

tr|L7N0S7|L7N0S7_CIOIN
ATP synthase subunit alpha
Search

ATP5A1

0.44	ATP synthase subunit alpha

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.69	GO:0099132	ATP hydrolysis coupled cation transmembrane transport

0.71	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.72	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)
0.44	GO:0005886	plasma membrane
0.42	GO:0005739	mitochondrion
0.33	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

tr|L7N0S8|L7N0S8_CIOIN
Uncharacterized protein
Search

0.82	DnaJ-like protein subfamily C member 13-like protein (Fragment)

0.85	GO:1902954	regulation of early endosome to recycling endosome transport
0.82	GO:2000641	regulation of early endosome to late endosome transport
0.77	GO:0007032	endosome organization
0.63	GO:0045022	early endosome to late endosome transport
0.55	GO:0006898	receptor-mediated endocytosis
0.42	GO:0001649	osteoblast differentiation
0.40	GO:0043312	neutrophil degranulation
0.36	GO:0015031	protein transport

0.35

GO:0005515

protein binding

0.78	GO:0031901	early endosome membrane
0.76	GO:0071203	WASH complex
0.66	GO:0005829	cytosol
0.52	GO:0043231	intracellular membrane-bounded organelle
0.42	GO:0070062	extracellular exosome
0.39	GO:0030667	secretory granule membrane
0.34	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0S9|L7N0S9_CIOIN
Uncharacterized protein
Search

0.49	GO:0009058	biosynthetic process
0.34	GO:0046146	tetrahydrobiopterin metabolic process
0.33	GO:0005975	carbohydrate metabolic process
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0034641	cellular nitrogen compound metabolic process
0.32	GO:0010468	regulation of gene expression
0.32	GO:0010467	gene expression
0.31	GO:0044260	cellular macromolecule metabolic process

0.67	GO:0030170	pyridoxal phosphate binding
0.50	GO:0008483	transaminase activity
0.34	GO:0008124	4-alpha-hydroxytetrahydrobiopterin dehydratase activity
0.34	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.33	GO:0003677	DNA binding
0.32	GO:0003700	DNA binding transcription factor activity

0.30

GO:0016020

membrane

0.50	EC:2.6.1	GO:0008483
0.34	KEGG:R04734	GO:0008124

tr|L7N0T0|L7N0T0_CIOIN
Uncharacterized protein
Search

0.55	E3 SUMO-protein ligase RanBP2 (Fragment)

0.69	GO:0046907	intracellular transport
0.55	GO:0000413	protein peptidyl-prolyl isomerization
0.51	GO:0006606	protein import into nucleus
0.51	GO:0046604	positive regulation of mitotic centrosome separation
0.50	GO:0006457	protein folding
0.49	GO:0090526	regulation of gluconeogenesis involved in cellular glucose homeostasis
0.49	GO:0033133	positive regulation of glucokinase activity
0.48	GO:0000082	G1/S transition of mitotic cell cycle
0.47	GO:0007051	spindle organization
0.46	GO:0043547	positive regulation of GTPase activity

0.56	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.51	GO:0008536	Ran GTPase binding
0.48	GO:0046872	metal ion binding
0.46	GO:0005096	GTPase activator activity
0.46	GO:0016874	ligase activity
0.36	GO:0031492	nucleosomal DNA binding
0.34	GO:0003723	RNA binding

0.48	GO:0005642	annulate lamellae
0.48	GO:0042405	nuclear inclusion body
0.47	GO:0044615	nuclear pore nuclear basket
0.46	GO:0044614	nuclear pore cytoplasmic filaments
0.46	GO:0005813	centrosome
0.45	GO:0031965	nuclear membrane
0.39	GO:0005739	mitochondrion
0.34	GO:0000785	chromatin
0.34	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.56

EC:5.2.1.8

GO:0003755

tr|L7N0T1|L7N0T1_CIOIN
Uncharacterized protein
Search

0.81	Actin alpha skeletal muscle

0.67	GO:0090131	mesenchyme migration
0.58	GO:0030240	skeletal muscle thin filament assembly
0.55	GO:0010628	positive regulation of gene expression
0.54	GO:0014706	striated muscle tissue development
0.54	GO:0007517	muscle organ development
0.51	GO:0014904	myotube cell development
0.51	GO:0048747	muscle fiber development
0.48	GO:0033275	actin-myosin filament sliding
0.46	GO:0055006	cardiac cell development
0.45	GO:0060047	heart contraction

0.52	GO:0032559	adenyl ribonucleotide binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0017022	myosin binding
0.39	GO:0016887	ATPase activity
0.35	GO:0031013	troponin I binding
0.35	GO:0031432	titin binding
0.35	GO:0048306	calcium-dependent protein binding
0.35	GO:0005523	tropomyosin binding
0.34	GO:0003785	actin monomer binding

0.63	GO:0030175	filopodium
0.62	GO:0030027	lamellipodium
0.60	GO:0044297	cell body
0.55	GO:0042641	actomyosin
0.54	GO:0005884	actin filament
0.54	GO:0030017	sarcomere
0.51	GO:0097517	contractile actin filament bundle
0.50	GO:0036379	myofilament
0.36	GO:0072562	blood microparticle
0.36	GO:0070062	extracellular exosome

0.39

GO:0016887

tr|L7N0T2|L7N0T2_CIOIN
Uncharacterized protein
Search

PRMT1

0.53	Protein arginine methyltransferase 1

0.73	GO:0008213	protein alkylation
0.67	GO:0043414	macromolecule methylation
0.46	GO:0018195	peptidyl-arginine modification
0.44	GO:0016570	histone modification
0.43	GO:0009790	embryo development
0.42	GO:0060026	convergent extension
0.37	GO:0045653	negative regulation of megakaryocyte differentiation
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:0010468	regulation of gene expression

0.63	GO:0008168	methyltransferase activity
0.37	GO:0140096	catalytic activity, acting on a protein
0.35	GO:0003713	transcription coactivator activity
0.32	GO:0005515	protein binding
0.32	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.32	GO:0016301	kinase activity
0.32	GO:0046872	metal ion binding

0.38	GO:0005829	cytosol
0.37	GO:0005654	nucleoplasm
0.32	GO:0043234	protein complex

0.63

GO:0008168

tr|L7N0T3|L7N0T3_CIOIN
Tubulin beta chain
Search

0.56	Tubulin beta chain

0.72	GO:0007017	microtubule-based process
0.71	GO:0007010	cytoskeleton organization
0.35	GO:0097711	ciliary basal body-plasma membrane docking
0.35	GO:0042267	natural killer cell mediated cytotoxicity
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0000086	G2/M transition of mitotic cell cycle
0.34	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.34	GO:0016567	protein ubiquitination

0.77	GO:0005200	structural constituent of cytoskeleton
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0032561	guanyl ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0003725	double-stranded RNA binding
0.35	GO:0042288	MHC class I protein binding
0.34	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0051082	unfolded protein binding
0.33	GO:0008270	zinc ion binding

0.73	GO:0005874	microtubule
0.47	GO:0043209	myelin sheath
0.45	GO:0005737	cytoplasm
0.35	GO:0031012	extracellular matrix
0.35	GO:0045298	tubulin complex
0.35	GO:0031983	vesicle lumen
0.34	GO:0030496	midbody
0.34	GO:0070062	extracellular exosome
0.34	GO:0097708	intracellular vesicle
0.33	GO:0012505	endomembrane system

0.34

GO:0004842

tr|L7N0T4|L7N0T4_CIOIN
Uncharacterized protein
Search

0.20	UTP--glucose-1-phosphate uridylyltransferase

0.77	GO:0006011	UDP-glucose metabolic process
0.41	GO:0005977	glycogen metabolic process
0.36	GO:0055093	response to hyperoxia
0.34	GO:0000103	sulfate assimilation
0.32	GO:0016310	phosphorylation

0.79	GO:0003983	UTP:glucose-1-phosphate uridylyltransferase activity
0.37	GO:0042802	identical protein binding
0.34	GO:0004020	adenylylsulfate kinase activity
0.34	GO:0004781	sulfate adenylyltransferase (ATP) activity
0.33	GO:0046872	metal ion binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.35	GO:0005737	cytoplasm
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.79	EC:2.7.7.9	GO:0003983
0.79	KEGG:R00289	GO:0003983

tr|L7N0T5|L7N0T5_CIOIN
Tubulin alpha chain
Search

0.53	Tubulin alpha chain

0.72	GO:0007017	microtubule-based process
0.71	GO:0007010	cytoskeleton organization
0.38	GO:0007094	mitotic spindle assembly checkpoint
0.34	GO:0019730	antimicrobial humoral response

0.77	GO:0005200	structural constituent of cytoskeleton
0.67	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.73	GO:0005874	microtubule
0.44	GO:0005737	cytoplasm
0.34	GO:0005818	aster
0.34	GO:0005813	centrosome
0.30	GO:0031224	intrinsic component of membrane

tr|L7N0T6|L7N0T6_CIOIN
Uncharacterized protein
Search

FZD1

0.92	Frizzled homolog 1 (Fragment)

0.76	GO:0016055	Wnt signaling pathway
0.67	GO:0007275	multicellular organism development
0.49	GO:0060429	epithelium development
0.47	GO:0009653	anatomical structure morphogenesis
0.46	GO:0042666	negative regulation of ectodermal cell fate specification
0.46	GO:0035412	regulation of catenin import into nucleus
0.46	GO:0014834	skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration
0.45	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing
0.45	GO:2000726	negative regulation of cardiac muscle cell differentiation
0.44	GO:0048103	somatic stem cell division

0.82	GO:0042813	Wnt-activated receptor activity
0.50	GO:0017147	Wnt-protein binding
0.46	GO:0005109	frizzled binding
0.45	GO:0030165	PDZ domain binding
0.44	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.42	GO:0004930	G-protein coupled receptor activity
0.41	GO:0004181	metallocarboxypeptidase activity
0.38	GO:0008270	zinc ion binding
0.35	GO:0045545	syndecan binding
0.35	GO:0001540	amyloid-beta binding

0.44	GO:0055038	recycling endosome membrane
0.39	GO:0005886	plasma membrane
0.37	GO:0009986	cell surface
0.35	GO:0106003	amyloid-beta complex
0.34	GO:0005923	bicellular tight junction
0.34	GO:0005769	early endosome
0.34	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0005794	Golgi apparatus
0.33	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane

0.41

EC:3.4.17

GO:0004181

tr|L7N0T7|L7N0T7_CIOIN
Uncharacterized protein
Search

tr|L7N0T8|L7N0T8_CIOIN
Uncharacterized protein
Search

0.12	integrin alpha-V

0.69	GO:0007229	integrin-mediated signaling pathway
0.61	GO:0007155	cell adhesion
0.35	GO:0002576	platelet degranulation
0.35	GO:0045652	regulation of megakaryocyte differentiation
0.34	GO:0002687	positive regulation of leukocyte migration
0.34	GO:0030168	platelet activation
0.34	GO:0030198	extracellular matrix organization

0.46	GO:0050840	extracellular matrix binding
0.43	GO:0042802	identical protein binding
0.35	GO:0070051	fibrinogen binding
0.33	GO:0046872	metal ion binding
0.32	GO:0003676	nucleic acid binding

0.67	GO:0008305	integrin complex
0.45	GO:0009897	external side of plasma membrane
0.45	GO:0005925	focal adhesion
0.45	GO:0070062	extracellular exosome
0.37	GO:0031092	platelet alpha granule membrane
0.34	GO:0072562	blood microparticle

tr|L7N0T9|L7N0T9_CIOIN
Uncharacterized protein
Search

tr|L7N0U0|L7N0U0_CIOIN
Uncharacterized protein
Search

tr|L7N0U1|L7N0U1_CIOIN
Uncharacterized protein
Search

0.40	glutathione S-transferase alpha-5-like

0.42	GO:0043651	linoleic acid metabolic process
0.42	GO:0030855	epithelial cell differentiation
0.41	GO:0006749	glutathione metabolic process
0.40	GO:0043390	aflatoxin B1 metabolic process
0.40	GO:0098754	detoxification
0.40	GO:1901685	glutathione derivative metabolic process
0.38	GO:0070887	cellular response to chemical stimulus
0.35	GO:0044272	sulfur compound biosynthetic process
0.35	GO:0070671	response to interleukin-12
0.34	GO:1901566	organonitrogen compound biosynthetic process

0.79	GO:0004364	glutathione transferase activity
0.40	GO:0004602	glutathione peroxidase activity
0.33	GO:0005515	protein binding

0.44	GO:0005829	cytosol
0.37	GO:0070062	extracellular exosome

0.79

EC:2.5.1.18

GO:0004364

tr|L7N0U2|L7N0U2_CIOIN
Uncharacterized protein
Search

0.69

GO:0016192

vesicle-mediated transport

0.30

GO:0044425

membrane part

tr|L7N0U3|L7N0U3_CIOIN
Uncharacterized protein
Search

JMJD6

0.51	Bifunctional arginine demethylase and lysyl-hydroxylase PSR

0.40	GO:0032259	methylation
0.39	GO:0010172	embryonic body morphogenesis
0.37	GO:0032956	regulation of actin cytoskeleton organization
0.37	GO:0098609	cell-cell adhesion
0.36	GO:0006260	DNA replication

0.41	GO:0008168	methyltransferase activity
0.38	GO:0045296	cadherin binding
0.34	GO:0003677	DNA binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.38	GO:0005913	cell-cell adherens junction
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.41

GO:0008168

tr|L7N0U4|L7N0U4_CIOIN
Uncharacterized protein
Search

tr|L7N0U5|L7N0U5_CIOIN
Uncharacterized protein
Search

0.63	solute carrier family 43 member 3-like

0.52	GO:0055085	transmembrane transport
0.32	GO:0006260	DNA replication
0.32	GO:0006281	DNA repair
0.32	GO:0015807	L-amino acid transport
0.32	GO:0015804	neutral amino acid transport
0.32	GO:0006351	transcription, DNA-templated
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.32	GO:0015179	L-amino acid transmembrane transporter activity
0.32	GO:0015175	neutral amino acid transmembrane transporter activity
0.32	GO:0003677	DNA binding

0.37	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm
0.33	GO:0005694	chromosome
0.32	GO:0005887	integral component of plasma membrane

tr|L7N0U6|L7N0U6_CIOIN
Uncharacterized protein
Search

DECR2

0.93	2-4-dienoyl-Coenzyme A reductase 2, peroxisomal

0.77	GO:0006636	unsaturated fatty acid biosynthetic process
0.51	GO:0055114	oxidation-reduction process
0.40	GO:0009062	fatty acid catabolic process
0.39	GO:0006228	UTP biosynthetic process
0.39	GO:0006183	GTP biosynthetic process
0.39	GO:0046036	CTP metabolic process
0.38	GO:0006165	nucleoside diphosphate phosphorylation
0.37	GO:0030258	lipid modification
0.37	GO:0030437	ascospore formation
0.35	GO:0006869	lipid transport

0.84	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity
0.82	GO:0008670	2,4-dienoyl-CoA reductase (NADPH) activity
0.67	GO:0005102	receptor binding
0.39	GO:0004550	nucleoside diphosphate kinase activity
0.38	GO:0008479	queuine tRNA-ribosyltransferase activity
0.38	GO:0005509	calcium ion binding
0.36	GO:1901612	cardiolipin binding
0.35	GO:0032403	protein complex binding
0.34	GO:0051020	GTPase binding
0.34	GO:0003735	structural constituent of ribosome

0.49	GO:0005777	peroxisome
0.43	GO:0044438	microbody part
0.41	GO:0098805	whole membrane
0.41	GO:0098588	bounding membrane of organelle
0.36	GO:0044437	vacuolar part
0.36	GO:0043233	organelle lumen
0.35	GO:0005829	cytosol
0.35	GO:0005634	nucleus
0.33	GO:0044429	mitochondrial part
0.33	GO:0031967	organelle envelope

0.84

EC:1.3.1.38

GO:0019166

tr|L7N0U7|L7N0U7_CIOIN
Sulfotransferase
Search

0.49	Cytosolic sulfotransferase

0.33	GO:0006805	xenobiotic metabolic process
0.33	GO:0006790	sulfur compound metabolic process

0.78

GO:0008146

sulfotransferase activity

0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.78

EC:2.8.2

GO:0008146

tr|L7N0U8|L7N0U8_CIOIN
Uncharacterized protein
Search

tr|L7N0V0|L7N0V0_CIOIN
Uncharacterized protein
Search

0.68	GO:0003924	GTPase activity
0.66	GO:0001883	purine nucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.65	GO:0032549	ribonucleoside binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0031224

intrinsic component of membrane

tr|L7N0V1|L7N0V1_CIOIN
Uncharacterized protein
Search

0.76	RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

0.58	GO:0007389	pattern specification process
0.49	GO:0036066	protein O-linked fucosylation
0.47	GO:0008593	regulation of Notch signaling pathway
0.46	GO:0032092	positive regulation of protein binding
0.44	GO:0009967	positive regulation of signal transduction
0.39	GO:0055016	hypochord development
0.38	GO:0030154	cell differentiation
0.38	GO:0007399	nervous system development
0.38	GO:0031101	fin regeneration
0.37	GO:0051961	negative regulation of nervous system development

0.65	GO:0016757	transferase activity, transferring glycosyl groups
0.40	GO:0046872	metal ion binding
0.32	GO:0016491	oxidoreductase activity

0.60	GO:0030173	integral component of Golgi membrane
0.34	GO:0070062	extracellular exosome

0.65

GO:0016757

tr|L7N0V2|L7N0V2_CIOIN
Uncharacterized protein
Search

tr|L7N0V3|L7N0V3_CIOIN
Uncharacterized protein
Search

tr|L7N0V4|L7N0V4_CIOIN
Uncharacterized protein
Search

tr|L7N0V5|L7N0V5_CIOIN
Uncharacterized protein
Search

0.66	GO:0008283	cell proliferation
0.37	GO:0007049	cell cycle
0.35	GO:0042254	ribosome biogenesis
0.34	GO:0007165	signal transduction

0.49	GO:0042802	identical protein binding
0.37	GO:0017137	Rab GTPase binding

0.72	GO:0005768	endosome
0.71	GO:0090545	CHD-type complex
0.69	GO:0090568	nuclear transcriptional repressor complex
0.68	GO:0000118	histone deacetylase complex
0.62	GO:0044433	cytoplasmic vesicle part
0.60	GO:0098805	whole membrane
0.59	GO:0098588	bounding membrane of organelle
0.39	GO:0070062	extracellular exosome

sp|O02367|CALM_CIOIN
Calmodulin
Search

0.44	Calmodulin (inferred by orthology to a C. elegans protein)

0.39	GO:0051296	establishment of meiotic spindle orientation
0.39	GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity
0.38	GO:0043277	apoptotic cell clearance
0.38	GO:0051343	positive regulation of cyclic-nucleotide phosphodiesterase activity
0.38	GO:0000086	G2/M transition of mitotic cell cycle
0.38	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity
0.38	GO:0005513	detection of calcium ion
0.38	GO:0051726	regulation of cell cycle
0.38	GO:0032516	positive regulation of phosphoprotein phosphatase activity
0.37	GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum

0.70	GO:0005509	calcium ion binding
0.39	GO:0019855	calcium channel inhibitor activity
0.38	GO:0031432	titin binding
0.38	GO:0008179	adenylate cyclase binding
0.38	GO:0072542	protein phosphatase activator activity
0.37	GO:0097718	disordered domain specific binding
0.37	GO:0031997	N-terminal myristoylation domain binding
0.37	GO:0044325	ion channel binding
0.36	GO:0030235	nitric-oxide synthase regulator activity
0.36	GO:0050998	nitric-oxide synthase binding

0.39	GO:0005819	spindle
0.38	GO:0005813	centrosome
0.38	GO:0043209	myelin sheath
0.37	GO:0031965	nuclear membrane
0.37	GO:0008076	voltage-gated potassium channel complex
0.36	GO:0030017	sarcomere
0.36	GO:0034704	calcium channel complex
0.36	GO:0030672	synaptic vesicle membrane
0.36	GO:0030426	growth cone
0.35	GO:0005874	microtubule

0.35

GO:0016705

tr|O18313|O18313_CIOIN
Hox 5
Search

0.42	Homeodomain transcription factor 4

0.68	GO:0007275	multicellular organism development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.50	GO:0009653	anatomical structure morphogenesis
0.48	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis
0.44	GO:0002376	immune system process
0.44	GO:0006366	transcription by RNA polymerase II
0.43	GO:1902680	positive regulation of RNA biosynthetic process
0.42	GO:0030154	cell differentiation

0.65	GO:0043565	sequence-specific DNA binding
0.60	GO:0003700	DNA binding transcription factor activity
0.44	GO:0001012	RNA polymerase II regulatory region DNA binding
0.42	GO:0003690	double-stranded DNA binding
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.41	GO:0005829	cytosol
0.41	GO:0031974	membrane-enclosed lumen
0.38	GO:0044446	intracellular organelle part

sp|O76808|SUH_CIOIN
Suppressor of hairless homolog
Search

RBPJ

0.91	Recombination signal binding protein for immunoglobulin kappa J region a

0.72	GO:0072148	epithelial cell fate commitment
0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.69	GO:0060840	artery development
0.69	GO:0001756	somitogenesis
0.68	GO:1905068	positive regulation of canonical Wnt signaling pathway involved in heart development
0.68	GO:1901189	positive regulation of ephrin receptor signaling pathway
0.68	GO:0035270	endocrine system development
0.67	GO:1901295	regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment
0.67	GO:0060485	mesenchyme development
0.66	GO:0060486	Clara cell differentiation

0.80	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.80	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.65	GO:0001103	RNA polymerase II repressing transcription factor binding
0.62	GO:0047485	protein N-terminus binding
0.61	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.57	GO:0003682	chromatin binding
0.36	GO:0032403	protein complex binding

0.68	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex
0.61	GO:0005634	nucleus
0.61	GO:0017053	transcriptional repressor complex
0.56	GO:0005667	transcription factor complex
0.52	GO:0070013	intracellular organelle lumen
0.48	GO:0043232	intracellular non-membrane-bounded organelle
0.47	GO:0044446	intracellular organelle part
0.41	GO:0005737	cytoplasm
0.36	GO:0032993	protein-DNA complex

sp|P16240|CION_CIOIN
Cionin
Search

0.56

Cionin

0.80	GO:0007218	neuropeptide signaling pathway
0.75	GO:0010469	regulation of receptor activity

0.79

GO:0005179

hormone activity

0.66

GO:0005576

extracellular region

sp|P61802|APTX_CIOIN
Aprataxin
Search

APTX

0.73

Aprataxin

0.64	GO:0006281	DNA repair
0.63	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.50	GO:0042542	response to hydrogen peroxide
0.48	GO:0031647	regulation of protein stability
0.46	GO:0006266	DNA ligation
0.44	GO:0016311	dephosphorylation
0.33	GO:0007264	small GTPase mediated signal transduction
0.33	GO:0006886	intracellular protein transport
0.32	GO:0065009	regulation of molecular function

0.85	GO:0033699	DNA 5'-adenosine monophosphate hydrolase activity
0.54	GO:0003677	DNA binding
0.50	GO:0047485	protein N-terminus binding
0.50	GO:0051219	phosphoprotein binding
0.50	GO:0120108	DNA-3'-diphospho-5'-guanosine diphosphatase
0.49	GO:0008967	phosphoglycolate phosphatase activity
0.47	GO:0003682	chromatin binding
0.47	GO:0003725	double-stranded RNA binding
0.38	GO:0046403	polynucleotide 3'-phosphatase activity
0.37	GO:0046872	metal ion binding

0.49	GO:0005730	nucleolus
0.48	GO:0005654	nucleoplasm
0.47	GO:0000790	nuclear chromatin
0.32	GO:0005737	cytoplasm

0.49	EC:3.1.3.18	GO:0008967
0.49	KEGG:R01334	GO:0008967

sp|P91580|RAB33_CIOIN
Putative Ras-related protein Rab-33
Search

RAB33B

0.86	Putative rab subfamily protein of small gtpase

0.56	GO:1903434	negative regulation of constitutive secretory pathway
0.55	GO:2000156	regulation of retrograde vesicle-mediated transport, Golgi to ER
0.54	GO:1903358	regulation of Golgi organization
0.53	GO:0000042	protein targeting to Golgi
0.51	GO:0048705	skeletal system morphogenesis
0.51	GO:2000785	regulation of autophagosome assembly
0.50	GO:0000045	autophagosome assembly
0.39	GO:0019882	antigen processing and presentation
0.36	GO:0050678	regulation of epithelial cell proliferation
0.35	GO:0001558	regulation of cell growth

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0004767	sphingomyelin phosphodiesterase activity
0.34	GO:0005515	protein binding
0.33	GO:0003723	RNA binding

0.54	GO:0005796	Golgi lumen
0.37	GO:0000139	Golgi membrane
0.36	GO:0070062	extracellular exosome
0.33	GO:0005886	plasma membrane

0.34	EC:3.1.4.12	GO:0004767
0.34	KEGG:R02541	GO:0004767

sp|Q07068|TPM1_CIOIN
Tropomyosin, smooth muscle/fibroblast CTM1
Search

0.29	Tropomyosin beta chain

0.68	GO:0006936	muscle contraction
0.63	GO:0060047	heart contraction
0.62	GO:0097435	supramolecular fiber organization
0.62	GO:0030036	actin cytoskeleton organization
0.58	GO:0048738	cardiac muscle tissue development
0.56	GO:0061061	muscle structure development
0.55	GO:0010927	cellular component assembly involved in morphogenesis
0.54	GO:0048468	cell development
0.53	GO:0003208	cardiac ventricle morphogenesis
0.53	GO:1904753	negative regulation of vascular associated smooth muscle cell migration

0.65	GO:0008307	structural constituent of muscle
0.60	GO:0051015	actin filament binding
0.44	GO:0042803	protein homodimerization activity
0.44	GO:0046982	protein heterodimerization activity
0.40	GO:0031013	troponin I binding
0.40	GO:0005200	structural constituent of cytoskeleton
0.39	GO:0097718	disordered domain specific binding
0.38	GO:0003924	GTPase activity
0.38	GO:0005525	GTP binding

0.69	GO:0015629	actin cytoskeleton
0.67	GO:0036379	myofilament
0.65	GO:0030017	sarcomere
0.62	GO:0044430	cytoskeletal part
0.53	GO:0032059	bleb
0.51	GO:0005829	cytosol
0.50	GO:0032587	ruffle membrane
0.40	GO:0097512	cardiac myofibril
0.38	GO:0030863	cortical cytoskeleton
0.38	GO:0043234	protein complex

tr|Q0E670|Q0E670_CIOIN
Putative CMP-sialic acid synthetase
Search

0.54	cytidine monophospho-N-acetylneuraminic acid synthetase

0.43	GO:0006054	N-acetylneuraminate metabolic process
0.37	GO:0006055	CMP-N-acetylneuraminate biosynthetic process
0.35	GO:0007268	chemical synaptic transmission
0.35	GO:0009408	response to heat
0.33	GO:0006468	protein phosphorylation
0.32	GO:0007165	signal transduction

0.62	GO:0008781	N-acylneuraminate cytidylyltransferase activity
0.42	GO:0090633	keto-deoxynonulosonic acid (KDN) cytidylyltransferase activity
0.42	GO:0090632	N-glycolylneuraminic acid (Neu5Gc) cytidylyltransferase activity
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003676	nucleic acid binding

0.39	GO:0005634	nucleus
0.35	GO:0005802	trans-Golgi network
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0005856	cytoskeleton
0.30	GO:0031224	intrinsic component of membrane

0.62

EC:2.7.7.43

GO:0008781

tr|Q0GTF8|Q0GTF8_CIOIN
Insulin-like 1
Search

0.76

GO:0010469

regulation of receptor activity

0.79

GO:0005179

hormone activity

0.66

GO:0005576

extracellular region

tr|Q19AW1|Q19AW1_CIOIN
Phox2
Search

0.60	Paired mesoderm homeobox protein 2B

0.70	GO:0003357	noradrenergic neuron differentiation
0.67	GO:0048857	neural nucleus development
0.65	GO:0048485	sympathetic nervous system development
0.64	GO:0030902	hindbrain development
0.64	GO:0043576	regulation of respiratory gaseous exchange
0.64	GO:0048486	parasympathetic nervous system development
0.62	GO:0021545	cranial nerve development
0.60	GO:0021953	central nervous system neuron differentiation
0.56	GO:0045944	positive regulation of transcription by RNA polymerase II
0.55	GO:0061548	ganglion development

0.60	GO:0043565	sequence-specific DNA binding
0.57	GO:0001012	RNA polymerase II regulatory region DNA binding
0.54	GO:0003690	double-stranded DNA binding
0.50	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding

0.60	GO:0005634	nucleus
0.54	GO:0000785	chromatin
0.51	GO:0043233	organelle lumen
0.30	GO:0031224	intrinsic component of membrane

sp|Q1JV40|HVCN1_CIOIN
Voltage-gated hydrogen channel 1
Search

0.52	Voltage-gated hydrogen channel 1

0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0071294	cellular response to zinc ion
0.58	GO:0071467	cellular response to pH
0.52	GO:0034765	regulation of ion transmembrane transport
0.38	GO:0045493	xylan catabolic process

0.86	GO:0030171	voltage-gated proton channel activity
0.40	GO:0042802	identical protein binding
0.36	GO:0016798	hydrolase activity, acting on glycosyl bonds

0.67

GO:0005887

integral component of plasma membrane

0.36

EC:3.2

GO:0016798

tr|Q1RL20|Q1RL20_CIOIN
Zic-like protein (Fragment)
Search

0.44	zinc finger protein ZIC 3

0.39	GO:0001841	neural tube formation
0.38	GO:0030154	cell differentiation
0.38	GO:0007420	brain development
0.37	GO:0061351	neural precursor cell proliferation
0.37	GO:0060070	canonical Wnt signaling pathway
0.36	GO:0051960	regulation of nervous system development
0.36	GO:0060284	regulation of cell development
0.36	GO:0060606	tube closure
0.36	GO:0042127	regulation of cell proliferation
0.35	GO:0045893	positive regulation of transcription, DNA-templated

0.51	GO:0003676	nucleic acid binding
0.34	GO:0046872	metal ion binding
0.34	GO:0003700	DNA binding transcription factor activity

0.36	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

tr|Q1RL21|Q1RL21_CIOIN
Zic-like protein (Fragment)
Search

0.60	zinc finger protein ZIC 4

0.45	GO:0001841	neural tube formation
0.45	GO:0033278	cell proliferation in midbrain
0.43	GO:0060070	canonical Wnt signaling pathway
0.43	GO:0030154	cell differentiation
0.42	GO:0051960	regulation of nervous system development
0.42	GO:0060284	regulation of cell development
0.41	GO:0042127	regulation of cell proliferation
0.37	GO:0060606	tube closure
0.37	GO:0030900	forebrain development
0.36	GO:0045893	positive regulation of transcription, DNA-templated

0.50	GO:0003676	nucleic acid binding
0.35	GO:0046872	metal ion binding
0.34	GO:0003700	DNA binding transcription factor activity

0.37

GO:0005634

nucleus

tr|Q1RL25|Q1RL25_CIOIN
Ubiquitinyl hydrolase 1
Search

0.35	Ubiquitinyl hydrolase 1

0.75	GO:0016579	protein deubiquitination
0.72	GO:0006511	ubiquitin-dependent protein catabolic process
0.51	GO:1904667	negative regulation of ubiquitin protein ligase activity
0.43	GO:0000398	mRNA splicing, via spliceosome
0.43	GO:0016570	histone modification
0.34	GO:0090266	regulation of mitotic cell cycle spindle assembly checkpoint
0.33	GO:0010498	proteasomal protein catabolic process
0.33	GO:0007059	chromosome segregation

0.76	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.62	GO:0008270	zinc ion binding
0.44	GO:0042393	histone binding
0.43	GO:0004197	cysteine-type endopeptidase activity

0.41

GO:0005634

nucleus

0.76

EC:3.4.19.12

GO:0036459

tr|Q1RL29|Q1RL29_CIOIN
Zinc finger protein (Fragment)
Search

0.36	Zinc finger protein (Fragment)

0.82	GO:0006471	protein ADP-ribosylation
0.51	GO:1990966	ATP generation from poly-ADP-D-ribose
0.51	GO:1903518	positive regulation of single strand break repair
0.50	GO:2001170	negative regulation of ATP biosynthetic process
0.49	GO:0043504	mitochondrial DNA repair
0.49	GO:0006302	double-strand break repair
0.49	GO:0006273	lagging strand elongation
0.48	GO:0051103	DNA ligation involved in DNA repair
0.48	GO:0018209	peptidyl-serine modification
0.47	GO:0032869	cellular response to insulin stimulus

0.80	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.62	GO:0008270	zinc ion binding
0.60	GO:0051287	NAD binding
0.54	GO:0003677	DNA binding
0.52	GO:1990404	protein ADP-ribosylase activity
0.48	GO:0047485	protein N-terminus binding
0.47	GO:0003910	DNA ligase (ATP) activity
0.46	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.45	GO:0019901	protein kinase binding
0.45	GO:0001067	regulatory region nucleic acid binding

0.56	GO:0005634	nucleus
0.44	GO:0005667	transcription factor complex
0.43	GO:0032993	protein-DNA complex
0.42	GO:0070013	intracellular organelle lumen
0.42	GO:0012505	endomembrane system
0.42	GO:0005739	mitochondrion
0.40	GO:0031967	organelle envelope
0.40	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

0.80

EC:2.4.2.30

GO:0003950

tr|Q1RL31|Q1RL31_CIOIN
Zinc finger protein (Fragment)
Search

0.74	abscission/NoCut checkpoint regulator isoform X1

0.54

GO:0046872

metal ion binding

tr|Q1RL32|Q1RL32_CIOIN
Zinc finger protein
Search

PLEKHF2

0.50	Pleckstrin homology and FYVE domain containing 2

0.36

GO:0015031

protein transport

0.54	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.50	GO:0030133	transport vesicle
0.38	GO:0031901	early endosome membrane
0.36	GO:0005783	endoplasmic reticulum

tr|Q1RL33|Q1RL33_CIOIN
Zinc finger protein
Search

ZMYND19

0.50	Melanin-concentrating hormone receptor 1

0.36	GO:0043043	peptide biosynthetic process
0.35	GO:0044267	cellular protein metabolic process
0.35	GO:0010467	gene expression
0.35	GO:0009059	macromolecule biosynthetic process

0.39	GO:0046872	metal ion binding
0.37	GO:0005515	protein binding
0.37	GO:0003735	structural constituent of ribosome

0.75	GO:0045202	synapse
0.49	GO:0005737	cytoplasm
0.39	GO:0005886	plasma membrane
0.36	GO:1990904	ribonucleoprotein complex
0.36	GO:0043232	intracellular non-membrane-bounded organelle

tr|Q1RL34|Q1RL34_CIOIN
Zinc finger protein (Fragment)
Search

SIRT2

0.57	NAD-dependent protein deacetylase

0.77	GO:0016575	histone deacetylation
0.50	GO:0061433	cellular response to caloric restriction
0.49	GO:2000777	positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia
0.49	GO:0061428	negative regulation of transcription from RNA polymerase II promoter in response to hypoxia
0.49	GO:0090042	tubulin deacetylation
0.49	GO:1900226	negative regulation of NLRP3 inflammasome complex assembly
0.49	GO:1900195	positive regulation of oocyte maturation
0.48	GO:0034983	peptidyl-lysine deacetylation
0.48	GO:0071872	cellular response to epinephrine stimulus
0.48	GO:1900119	positive regulation of execution phase of apoptosis

0.78	GO:0017136	NAD-dependent histone deacetylase activity
0.76	GO:0070403	NAD+ binding
0.61	GO:0008270	zinc ion binding
0.49	GO:0034739	histone deacetylase activity (H4-K16 specific)
0.49	GO:0042903	tubulin deacetylase activity
0.47	GO:0035035	histone acetyltransferase binding
0.46	GO:0042826	histone deacetylase binding
0.45	GO:0043130	ubiquitin binding
0.44	GO:0003682	chromatin binding
0.43	GO:0008134	transcription factor binding

0.49	GO:0033010	paranodal junction
0.48	GO:0043220	Schmidt-Lanterman incisure
0.47	GO:0072687	meiotic spindle
0.47	GO:0043204	perikaryon
0.46	GO:0030496	midbody
0.46	GO:0005814	centriole
0.45	GO:0072686	mitotic spindle
0.45	GO:0048471	perinuclear region of cytoplasm
0.44	GO:0005813	centrosome
0.43	GO:0005874	microtubule

0.34	EC:1.8.4 EC:1.8.4.12	GO:0033743
0.34	KEGG:R07607	GO:0033743

tr|Q1RL38|Q1RL38_CIOIN
Zinc finger protein
Search

0.27	zinc finger protein ZF(C2H2)-151

0.40	GO:0040034	regulation of development, heterochronic
0.38	GO:1903506	regulation of nucleic acid-templated transcription
0.38	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.38	GO:0010468	regulation of gene expression
0.33	GO:0007275	multicellular organism development
0.32	GO:0032259	methylation
0.32	GO:0006351	transcription, DNA-templated

0.51	GO:0003676	nucleic acid binding
0.38	GO:0046872	metal ion binding
0.37	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.33	GO:0008168	methyltransferase activity

0.39	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.33

GO:0008168

tr|Q1RL40|Q1RL40_CIOIN
Zinc finger protein (Fragment)
Search

MNAT1

0.58	MNAT CDK-activating kinase assembly factor 1

0.85	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity
0.73	GO:0006289	nucleotide-excision repair
0.53	GO:0007512	adult heart development
0.52	GO:0021591	ventricular system development
0.51	GO:0051592	response to calcium ion
0.51	GO:0016310	phosphorylation
0.48	GO:0006357	regulation of transcription by RNA polymerase II
0.48	GO:0006366	transcription by RNA polymerase II
0.46	GO:0045893	positive regulation of transcription, DNA-templated
0.44	GO:0036211	protein modification process

0.85	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity
0.55	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity
0.51	GO:0047485	protein N-terminus binding
0.45	GO:0008094	DNA-dependent ATPase activity
0.45	GO:0004693	cyclin-dependent protein serine/threonine kinase activity
0.35	GO:0008270	zinc ion binding
0.34	GO:0000990	transcription factor activity, core RNA polymerase binding
0.34	GO:0016874	ligase activity
0.32	GO:0003677	DNA binding

0.83	GO:0005675	holo TFIIH complex
0.45	GO:0005829	cytosol
0.35	GO:0042585	germinal vesicle
0.33	GO:0005694	chromosome

0.55

EC:2.7.11.23

GO:0008353

tr|Q1RL41|Q1RL41_CIOIN
Palmitoyltransferase (Fragment)
Search

ZDHHC16

0.54	Palmitoyltransferase

0.51	GO:0018345	protein palmitoylation
0.49	GO:0048513	animal organ development
0.48	GO:0072359	circulatory system development
0.44	GO:0060322	head development
0.43	GO:0007417	central nervous system development
0.43	GO:0006974	cellular response to DNA damage stimulus
0.43	GO:0048663	neuron fate commitment
0.42	GO:0008543	fibroblast growth factor receptor signaling pathway
0.38	GO:0006915	apoptotic process

0.80	GO:0019706	protein-cysteine S-palmitoyltransferase activity
0.34	GO:0005515	protein binding

0.38	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.80

EC:2.3.1.225

GO:0019706

tr|Q1RL43|Q1RL43_CIOIN
Zinc finger protein (Fragment)
Search

0.10	Zinc finger protein (Fragment)

0.47	GO:1903506	regulation of nucleic acid-templated transcription
0.47	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.47	GO:0010468	regulation of gene expression
0.35	GO:1902679	negative regulation of RNA biosynthetic process
0.35	GO:0002244	hematopoietic progenitor cell differentiation
0.34	GO:0006351	transcription, DNA-templated
0.34	GO:0072707	cellular response to sodium dodecyl sulfate
0.33	GO:0032259	methylation
0.33	GO:0045654	positive regulation of megakaryocyte differentiation
0.33	GO:0045648	positive regulation of erythrocyte differentiation

0.51	GO:0003676	nucleic acid binding
0.45	GO:0046872	metal ion binding
0.39	GO:0003700	DNA binding transcription factor activity
0.33	GO:0008168	methyltransferase activity
0.33	GO:0005515	protein binding

0.40	GO:0005622	intracellular
0.37	GO:0043227	membrane-bounded organelle
0.32	GO:0031974	membrane-enclosed lumen
0.32	GO:0043228	non-membrane-bounded organelle
0.32	GO:0044422	organelle part
0.30	GO:0016020	membrane

0.33

GO:0008168

tr|Q1RL44|Q1RL44_CIOIN
Zinc finger protein
Search

UNK

0.42	RING finger protein unkempt

0.37	GO:2000766	negative regulation of cytoplasmic translation
0.36	GO:0030182	neuron differentiation
0.36	GO:0001764	neuron migration
0.36	GO:0009653	anatomical structure morphogenesis
0.35	GO:0048468	cell development
0.35	GO:0022416	chaeta development
0.34	GO:0002164	larval development
0.34	GO:0048749	compound eye development
0.34	GO:0048737	imaginal disc-derived appendage development
0.34	GO:0035220	wing disc development

0.54	GO:0046872	metal ion binding
0.41	GO:0016874	ligase activity
0.37	GO:1990715	mRNA CDS binding
0.33	GO:0005515	protein binding
0.32	GO:0003677	DNA binding

0.36	GO:0005844	polysome
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.41

GO:0016874

tr|Q1RL46|Q1RL46_CIOIN
Zinc finger protein
Search

0.10	Zinc finger protein

0.54

GO:0046872

metal ion binding

tr|Q1RL48|Q1RL48_CIOIN
Zinc finger protein (Fragment)
Search

MIB1

0.59	E3 ubiquitin-protein ligase mind-bomb

0.73	GO:0016567	protein ubiquitination
0.49	GO:0007219	Notch signaling pathway
0.48	GO:0001756	somitogenesis
0.47	GO:0001947	heart looping
0.47	GO:0021915	neural tube development
0.47	GO:0016331	morphogenesis of embryonic epithelium
0.47	GO:0045807	positive regulation of endocytosis
0.47	GO:0072175	epithelial tube formation
0.47	GO:0045665	negative regulation of neuron differentiation
0.46	GO:0001568	blood vessel development

0.74	GO:0004842	ubiquitin-protein transferase activity
0.63	GO:0008270	zinc ion binding
0.55	GO:0016874	ligase activity
0.34	GO:0005515	protein binding

0.45	GO:0005813	centrosome
0.43	GO:0031410	cytoplasmic vesicle
0.36	GO:0014069	postsynaptic density
0.34	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0000151	ubiquitin ligase complex
0.34	GO:0005886	plasma membrane
0.33	GO:0005829	cytosol
0.33	GO:0043234	protein complex

0.55	EC:6	GO:0016874
0.74	KEGG:R03876	GO:0004842

tr|Q1RL49|Q1RL49_CIOIN
Zinc finger protein
Search

RNF14

0.53	RING-type E3 ubiquitin transferase

0.72	GO:0016567	protein ubiquitination
0.55	GO:0060765	regulation of androgen receptor signaling pathway
0.49	GO:0051173	positive regulation of nitrogen compound metabolic process
0.49	GO:0010604	positive regulation of macromolecule metabolic process
0.49	GO:0031325	positive regulation of cellular metabolic process
0.48	GO:0009891	positive regulation of biosynthetic process
0.48	GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process
0.46	GO:0009896	positive regulation of catabolic process
0.44	GO:0006511	ubiquitin-dependent protein catabolic process
0.42	GO:0006355	regulation of transcription, DNA-templated

0.73	GO:0004842	ubiquitin-protein transferase activity
0.55	GO:0050681	androgen receptor binding
0.53	GO:0046872	metal ion binding
0.50	GO:0016874	ligase activity
0.49	GO:0031624	ubiquitin conjugating enzyme binding
0.45	GO:0061659	ubiquitin-like protein ligase activity
0.34	GO:0003713	transcription coactivator activity
0.33	GO:0051537	2 iron, 2 sulfur cluster binding

0.47	GO:0005829	cytosol
0.45	GO:0000151	ubiquitin ligase complex
0.45	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.50	EC:6	GO:0016874
0.73	KEGG:R03876	GO:0004842

tr|Q1RL50|Q1RL50_CIOIN
Zinc finger protein
Search

ASAP1

0.50	Arf-GAP with SH3 domain ANK repeat and PH domain-containing protein 1

0.76	GO:0043547	positive regulation of GTPase activity
0.52	GO:1903527	positive regulation of membrane tubulation
0.51	GO:0061000	negative regulation of dendritic spine development
0.51	GO:0071803	positive regulation of podosome assembly
0.48	GO:0060271	cilium assembly
0.33	GO:0005975	carbohydrate metabolic process

0.76	GO:0005096	GTPase activator activity
0.53	GO:0046872	metal ion binding
0.50	GO:0001786	phosphatidylserine binding
0.50	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.49	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.48	GO:0045296	cadherin binding
0.34	GO:0032266	phosphatidylinositol-3-phosphate binding
0.34	GO:0017124	SH3 domain binding

0.50	GO:0002102	podosome
0.49	GO:0043197	dendritic spine
0.48	GO:0031253	cell projection membrane
0.35	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|Q1RL53|Q1RL53_CIOIN
Zinc finger protein
Search

0.10	Zinc finger protein

0.63	GO:0008270	zinc ion binding
0.51	GO:0003676	nucleic acid binding

tr|Q1RL57|Q1RL57_CIOIN
Zinc finger protein
Search

0.44	zinc finger protein (MYND)-8

tr|Q1RL58|Q1RL58_CIOIN
DNA ligase (Fragment)
Search

LIG3

0.47	DNA ligase

0.80	GO:0051103	DNA ligation involved in DNA repair
0.67	GO:0071897	DNA biosynthetic process
0.66	GO:0006260	DNA replication
0.65	GO:0006310	DNA recombination
0.57	GO:0090298	negative regulation of mitochondrial DNA replication
0.52	GO:0006302	double-strand break repair
0.49	GO:0006284	base-excision repair
0.47	GO:0022616	DNA strand elongation
0.43	GO:0000726	non-recombinational repair
0.38	GO:0016070	RNA metabolic process

0.79	GO:0003910	DNA ligase (ATP) activity
0.62	GO:0008270	zinc ion binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.55	GO:0003677	DNA binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0004252	serine-type endopeptidase activity
0.33	GO:0005515	protein binding
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding

0.47	GO:0005654	nucleoplasm
0.40	GO:0005739	mitochondrion
0.38	GO:0070421	DNA ligase III-XRCC1 complex
0.35	GO:0000795	synaptonemal complex

0.79

EC:6.5.1.1

GO:0003910

tr|Q1RL59|Q1RL59_CIOIN
Zinc finger protein
Search

0.27	zinc finger protein ZF(ZZ)-4

0.43	GO:0048172	regulation of short-term neuronal synaptic plasticity
0.43	GO:0008586	imaginal disc-derived wing vein morphogenesis
0.43	GO:0007474	imaginal disc-derived wing vein specification
0.42	GO:0046716	muscle cell cellular homeostasis
0.42	GO:0007274	neuromuscular synaptic transmission
0.42	GO:0046928	regulation of neurotransmitter secretion
0.41	GO:0030010	establishment of cell polarity
0.36	GO:0007517	muscle organ development

0.63	GO:0008270	zinc ion binding
0.58	GO:0003779	actin binding
0.43	GO:0050699	WW domain binding
0.38	GO:0008307	structural constituent of muscle

0.42	GO:0016010	dystrophin-associated glycoprotein complex
0.40	GO:0045202	synapse
0.39	GO:0005856	cytoskeleton
0.38	GO:0042383	sarcolemma
0.37	GO:0005938	cell cortex

tr|Q1RL62|Q1RL62_CIOIN
Zinc finger protein
Search

0.29	zinc finger protein 79-like

0.41	GO:1903506	regulation of nucleic acid-templated transcription
0.41	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.41	GO:0010468	regulation of gene expression
0.35	GO:0040034	regulation of development, heterochronic
0.34	GO:0060216	definitive hemopoiesis
0.34	GO:0030218	erythrocyte differentiation
0.33	GO:0006351	transcription, DNA-templated

0.51	GO:0003676	nucleic acid binding
0.41	GO:0046872	metal ion binding
0.36	GO:0003700	DNA binding transcription factor activity

0.38	GO:0005634	nucleus
0.34	GO:0005694	chromosome
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

tr|Q1RL63|Q1RL63_CIOIN
Zinc finger protein
Search

ZNF706

0.51	Zinc finger protein 706

0.85	GO:1902455	negative regulation of stem cell population maintenance
0.69	GO:0045892	negative regulation of transcription, DNA-templated
0.42	GO:0006417	regulation of translation

0.38	GO:0019904	protein domain specific binding
0.37	GO:0046872	metal ion binding
0.33	GO:0016787	hydrolase activity

0.59	GO:0005634	nucleus
0.47	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0016787

tr|Q1RL67|Q1RL67_CIOIN
Zinc finger protein
Search

0.23	Zinc finger protein 65 (Fragment)

0.47	GO:1903506	regulation of nucleic acid-templated transcription
0.47	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.46	GO:0010468	regulation of gene expression
0.43	GO:0070895	negative regulation of transposon integration
0.39	GO:1902679	negative regulation of RNA biosynthetic process
0.35	GO:0006351	transcription, DNA-templated
0.33	GO:0006886	intracellular protein transport
0.33	GO:0048015	phosphatidylinositol-mediated signaling
0.33	GO:0016573	histone acetylation
0.33	GO:0040034	regulation of development, heterochronic

0.51	GO:0003676	nucleic acid binding
0.45	GO:0046872	metal ion binding
0.41	GO:0003700	DNA binding transcription factor activity
0.33	GO:0016301	kinase activity

0.41	GO:0005634	nucleus
0.34	GO:0043233	organelle lumen
0.33	GO:1902493	acetyltransferase complex
0.33	GO:0044446	intracellular organelle part
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

tr|Q1RL70|Q1RL70_CIOIN
Zinc finger protein
Search

RBCK1

0.48	ranBP-type and C3HC4-type zinc finger-containing protein 1

0.57	GO:0097039	protein linear polyubiquitination
0.52	GO:0060546	negative regulation of necroptotic process
0.52	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.51	GO:0042345	regulation of NF-kappaB import into nucleus
0.51	GO:0042993	positive regulation of transcription factor import into nucleus
0.51	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway
0.51	GO:0050852	T cell receptor signaling pathway
0.51	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.50	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.50	GO:0051092	positive regulation of NF-kappaB transcription factor activity

0.53	GO:0046872	metal ion binding
0.53	GO:0043130	ubiquitin binding
0.49	GO:0004842	ubiquitin-protein transferase activity
0.34	GO:0005080	protein kinase C binding
0.34	GO:0016874	ligase activity
0.33	GO:0003690	double-stranded DNA binding
0.33	GO:0003700	DNA binding transcription factor activity
0.33	GO:0016301	kinase activity

0.55	GO:0071797	LUBAC complex
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.34	EC:6	GO:0016874
0.49	KEGG:R03876	GO:0004842

tr|Q1RL72|Q1RL72_CIOIN
Zinc finger protein
Search

0.44	zinc finger protein (ZZ-type)-2

0.73

GO:0016567

protein ubiquitination

0.74	GO:0004842	ubiquitin-protein transferase activity
0.63	GO:0008270	zinc ion binding

0.74

GO:0004842

tr|Q1RL74|Q1RL74_CIOIN
Zinc finger protein
Search

0.30	zinc finger protein 1

0.33	GO:0006351	transcription, DNA-templated
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.61	GO:0008270	zinc ion binding
0.54	GO:0003677	DNA binding
0.32	GO:0005515	protein binding

0.46	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex
0.43	GO:0005730	nucleolus

tr|Q1RL76|Q1RL76_CIOIN
Zinc finger protein (Fragment)
Search

0.49	Zinc finger protein (Fragment)

0.75	GO:2000026	regulation of multicellular organismal development
0.71	GO:0006357	regulation of transcription by RNA polymerase II

0.61

GO:0003700

DNA binding transcription factor activity

0.61

GO:0005634

nucleus

tr|Q1RL77|Q1RL77_CIOIN
Zinc finger protein (Fragment)
Search

ZMIZ1

0.39	Zinc finger MIZ domain-containing protein 1

0.45	GO:0007296	vitellogenesis
0.44	GO:0048146	positive regulation of fibroblast proliferation
0.44	GO:0048844	artery morphogenesis
0.44	GO:0045582	positive regulation of T cell differentiation
0.44	GO:0001570	vasculogenesis
0.44	GO:0045747	positive regulation of Notch signaling pathway
0.43	GO:0007569	cell aging
0.43	GO:0045944	positive regulation of transcription by RNA polymerase II
0.43	GO:0003007	heart morphogenesis
0.43	GO:0048589	developmental growth

0.63	GO:0008270	zinc ion binding
0.37	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.35	GO:0016874	ligase activity
0.33	GO:0005509	calcium ion binding

0.41	GO:0005654	nucleoplasm
0.37	GO:0043596	nuclear replication fork
0.33	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.35

GO:0016874

tr|Q1RL78|Q1RL78_CIOIN
Zinc finger protein (Fragment)
Search

0.41	zinc finger and BTB domain-containing protein 41 isoform X4

0.47

GO:0006508

proteolysis

0.65	GO:0071567	UFM1 hydrolase activity
0.51	GO:0003676	nucleic acid binding
0.38	GO:0046983	protein dimerization activity

tr|Q1RL82|Q1RL82_CIOIN
Transcription factor protein
Search

POLE3

0.80	DNA polymerase epsilon subunit 3

0.53	GO:0043966	histone H3 acetylation
0.38	GO:0071897	DNA biosynthetic process
0.35	GO:0032201	telomere maintenance via semi-conservative replication
0.34	GO:0000082	G1/S transition of mitotic cell cycle
0.34	GO:0043044	ATP-dependent chromatin remodeling
0.34	GO:0006270	DNA replication initiation
0.33	GO:0006779	porphyrin-containing compound biosynthetic process

0.74	GO:0046982	protein heterodimerization activity
0.38	GO:0003887	DNA-directed DNA polymerase activity
0.35	GO:0003677	DNA binding
0.34	GO:0031491	nucleosome binding
0.33	GO:0004655	porphobilinogen synthase activity
0.33	GO:0004386	helicase activity
0.33	GO:0016887	ATPase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding

0.58	GO:0005634	nucleus
0.50	GO:0031248	protein acetyltransferase complex
0.49	GO:0042575	DNA polymerase complex
0.47	GO:0044427	chromosomal part
0.46	GO:0031974	membrane-enclosed lumen
0.43	GO:0043234	protein complex
0.33	GO:1904949	ATPase complex

0.38	EC:2.7.7.7	GO:0003887
0.33	KEGG:R00036	GO:0004655

tr|Q1RL83|Q1RL83_CIOIN
Zinc finger protein
Search

MIB2

0.39	Mindbomb E3 ubiquitin protein ligase 2

0.73	GO:0016567	protein ubiquitination
0.37	GO:0007219	Notch signaling pathway
0.36	GO:0030318	melanocyte differentiation
0.36	GO:0002090	regulation of receptor internalization
0.36	GO:0048522	positive regulation of cellular process
0.35	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling
0.35	GO:0031396	regulation of protein ubiquitination
0.35	GO:0023056	positive regulation of signaling
0.35	GO:0048584	positive regulation of response to stimulus
0.35	GO:0051247	positive regulation of protein metabolic process

0.74	GO:0004842	ubiquitin-protein transferase activity
0.62	GO:0008270	zinc ion binding
0.53	GO:0016874	ligase activity
0.44	GO:0061659	ubiquitin-like protein ligase activity
0.36	GO:0008092	cytoskeletal protein binding
0.35	GO:0004222	metalloendopeptidase activity
0.35	GO:0042803	protein homodimerization activity
0.34	GO:0004871	signal transducer activity
0.33	GO:0102567	phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
0.33	GO:0102568	phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)

0.45	GO:0005769	early endosome
0.45	GO:0000151	ubiquitin ligase complex
0.36	GO:0031012	extracellular matrix
0.35	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0031430	M band
0.34	GO:0030018	Z disc
0.33	GO:0005829	cytosol

0.53	EC:6	GO:0016874
0.74	KEGG:R03876	GO:0004842

tr|Q1RL87|Q1RL87_CIOIN
Zinc finger protein (Fragment)
Search

0.46	AN1-type zinc finger protein 1

0.40	GO:0010200	response to chitin
0.39	GO:0009737	response to abscisic acid
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process

0.63	GO:0008270	zinc ion binding
0.44	GO:0003676	nucleic acid binding
0.33	GO:0003735	structural constituent of ribosome
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.33	GO:0015935	small ribosomal subunit
0.30	GO:0031224	intrinsic component of membrane

tr|Q1RL89|Q1RL89_CIOIN
Zinc finger protein
Search

0.27	zinc finger protein ZF(C2H2)-132

0.42	GO:0010272	response to silver ion
0.42	GO:0061321	garland nephrocyte differentiation
0.41	GO:0036059	nephrocyte diaphragm assembly
0.41	GO:0061320	pericardial nephrocyte differentiation
0.39	GO:0000122	negative regulation of transcription by RNA polymerase II
0.35	GO:0045944	positive regulation of transcription by RNA polymerase II
0.33	GO:0006470	protein dephosphorylation
0.32	GO:0032259	methylation
0.32	GO:0006351	transcription, DNA-templated

0.51	GO:0003676	nucleic acid binding
0.37	GO:0046872	metal ion binding
0.34	GO:0003700	DNA binding transcription factor activity
0.34	GO:0004722	protein serine/threonine phosphatase activity
0.32	GO:0008168	methyltransferase activity

0.35	GO:0005622	intracellular
0.33	GO:0043227	membrane-bounded organelle
0.30	GO:0016020	membrane

0.32

GO:0008168

tr|Q1RL92|Q1RL92_CIOIN
Zinc finger protein
Search

0.30	zinc finger protein 130

0.57	GO:0048730	epidermis morphogenesis
0.57	GO:0045892	negative regulation of transcription, DNA-templated
0.56	GO:0007423	sensory organ development
0.51	GO:0006357	regulation of transcription by RNA polymerase II
0.48	GO:0048562	embryonic organ morphogenesis
0.47	GO:0060023	soft palate development
0.45	GO:0009952	anterior/posterior pattern specification
0.41	GO:1904888	cranial skeletal system development
0.41	GO:0048706	embryonic skeletal system development
0.41	GO:0048705	skeletal system morphogenesis

0.55	GO:0003682	chromatin binding
0.51	GO:0003677	DNA binding
0.50	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.34	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.47	GO:0005634	nucleus
0.33	GO:0030176	integral component of endoplasmic reticulum membrane

tr|Q1RL93|Q1RL93_CIOIN
Zinc finger protein
Search

RUFY1

0.82	RUN and FYVE domain-containing protein 1

0.52	GO:0030100	regulation of endocytosis
0.44	GO:0015031	protein transport
0.36	GO:0006897	endocytosis
0.35	GO:0006661	phosphatidylinositol biosynthetic process

0.55	GO:0042169	SH2 domain binding
0.52	GO:0046872	metal ion binding
0.51	GO:0017124	SH3 domain binding
0.46	GO:0008565	protein transporter activity
0.36	GO:0008289	lipid binding

0.51	GO:0016607	nuclear speck
0.49	GO:0005768	endosome
0.46	GO:0005829	cytosol
0.37	GO:0044433	cytoplasmic vesicle part
0.36	GO:0098805	whole membrane
0.36	GO:0098588	bounding membrane of organelle

tr|Q1RL96|Q1RL96_CIOIN
Zinc finger protein
Search

0.10	Zinc finger protein

0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression
0.51	GO:0097659	nucleic acid-templated transcription
0.48	GO:0010467	gene expression
0.47	GO:0034645	cellular macromolecule biosynthetic process

0.51	GO:0003676	nucleic acid binding
0.50	GO:0046872	metal ion binding

0.40

GO:0005622

intracellular

tr|Q1RL99|Q1RL99_CIOIN
Zinc finger protein (Fragment)
Search

0.49	Zinc finger protein (Fragment)

0.63	GO:0008270	zinc ion binding
0.51	GO:0003676	nucleic acid binding

tr|Q1RLA1|Q1RLA1_CIOIN
Zinc finger protein (Fragment)
Search

0.37	Zinc finger protein (Fragment)

0.40	GO:1903506	regulation of nucleic acid-templated transcription
0.40	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.40	GO:0010468	regulation of gene expression
0.39	GO:0031335	regulation of sulfur amino acid metabolic process
0.36	GO:1902680	positive regulation of RNA biosynthetic process
0.36	GO:1902679	negative regulation of RNA biosynthetic process
0.35	GO:0007346	regulation of mitotic cell cycle

0.51	GO:0003676	nucleic acid binding
0.39	GO:0001133	RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding
0.38	GO:0046872	metal ion binding
0.36	GO:0001102	RNA polymerase II activating transcription factor binding

0.35	GO:0005622	intracellular
0.33	GO:0043227	membrane-bounded organelle

tr|Q1RLA5|Q1RLA5_CIOIN
Zinc finger protein (Fragment)
Search

U2AF1

0.55	U2 small nuclear RNA auxiliary factor small subunit

0.75	GO:0000398	mRNA splicing, via spliceosome
0.43	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.36	GO:1903146	regulation of autophagy of mitochondrion
0.36	GO:1903955	positive regulation of protein targeting to mitochondrion
0.34	GO:0006369	termination of RNA polymerase II transcription
0.34	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.34	GO:0031124	mRNA 3'-end processing
0.34	GO:0051028	mRNA transport
0.34	GO:0006405	RNA export from nucleus

0.59	GO:0003723	RNA binding
0.54	GO:0046872	metal ion binding
0.48	GO:0050733	RS domain binding

0.84	GO:0089701	U2AF
0.46	GO:0016607	nuclear speck
0.45	GO:0005681	spliceosomal complex
0.34	GO:0015030	Cajal body
0.34	GO:1902494	catalytic complex
0.33	GO:0019013	viral nucleocapsid
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|Q1RLA7|Q1RLA7_CIOIN
Zinc finger protein (Fragment)
Search

0.37	Ankyrin repeat and FYVE domain-containing protein 1

0.55	GO:0048549	positive regulation of pinocytosis
0.54	GO:0090160	Golgi to lysosome transport
0.53	GO:0034058	endosomal vesicle fusion
0.53	GO:0032439	endosome localization
0.50	GO:0042147	retrograde transport, endosome to Golgi
0.35	GO:0006897	endocytosis
0.34	GO:0046854	phosphatidylinositol phosphorylation

0.53	GO:0046872	metal ion binding
0.50	GO:0017137	Rab GTPase binding
0.50	GO:1901981	phosphatidylinositol phosphate binding
0.35	GO:0000285	1-phosphatidylinositol-3-phosphate 5-kinase activity
0.34	GO:0102568	phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
0.34	GO:0102567	phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
0.34	GO:0004623	phospholipase A2 activity

0.54	GO:0044352	pinosome
0.50	GO:0030904	retromer complex
0.50	GO:0005769	early endosome
0.49	GO:0010008	endosome membrane
0.45	GO:0005829	cytosol
0.40	GO:0043231	intracellular membrane-bounded organelle
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.35	EC:2.7.1.150	GO:0000285
0.35	KEGG:R05802	GO:0000285

tr|Q1RLB1|Q1RLB1_CIOIN
Zinc finger protein
Search

TRIM55

0.51	Tripartite motif-containing protein 55

0.48	GO:0055001	muscle cell development
0.47	GO:0070507	regulation of microtubule cytoskeleton organization
0.38	GO:1901880	negative regulation of protein depolymerization
0.38	GO:1902904	negative regulation of supramolecular fiber organization
0.38	GO:0051494	negative regulation of cytoskeleton organization
0.34	GO:0098655	cation transmembrane transport
0.33	GO:0007275	multicellular organism development
0.33	GO:0007165	signal transduction

0.63	GO:0008270	zinc ion binding
0.46	GO:0042802	identical protein binding
0.37	GO:0016874	ligase activity
0.37	GO:0008017	microtubule binding
0.34	GO:0008324	cation transmembrane transporter activity
0.33	GO:0004871	signal transducer activity

0.45	GO:0005622	intracellular
0.44	GO:0099512	supramolecular fiber
0.40	GO:0043228	non-membrane-bounded organelle
0.39	GO:0044422	organelle part
0.35	GO:0043234	protein complex
0.33	GO:0043227	membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

0.37

GO:0016874

tr|Q1RLB9|Q1RLB9_CIOIN
Transcription factor protein
Search

0.51	transcription factor ATBF

0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:0010468	regulation of gene expression

0.63	GO:0043565	sequence-specific DNA binding
0.48	GO:0008270	zinc ion binding

0.61

GO:0005634

nucleus

tr|Q1RLC2|Q1RLC2_CIOIN
Zinc finger protein (Fragment)
Search

0.49	Zinc finger protein (Fragment)

tr|Q1RLC3|Q1RLC3_CIOIN
Zinc finger protein
Search

CYHR1

0.51	Cysteine and histidine-rich protein 1-A

0.34	GO:0006511	ubiquitin-dependent protein catabolic process
0.33	GO:0007275	multicellular organism development
0.33	GO:0016310	phosphorylation

0.58	GO:0008270	zinc ion binding
0.34	GO:0005515	protein binding
0.33	GO:0016301	kinase activity
0.32	GO:0016874	ligase activity

0.45	GO:0005654	nucleoplasm
0.38	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0005635	nuclear envelope
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016874

sp|Q1RLC9|RU1C_CIOIN
U1 small nuclear ribonucleoprotein C
Search

SNRPC

0.73	U1 small nuclear ribonucleoprotein C

0.81	GO:0000395	mRNA 5'-splice site recognition
0.81	GO:0000387	spliceosomal snRNP assembly
0.40	GO:0000381	regulation of alternative mRNA splicing, via spliceosome

0.78	GO:0030619	U1 snRNA binding
0.69	GO:0003729	mRNA binding
0.63	GO:0008270	zinc ion binding
0.49	GO:0030627	pre-mRNA 5'-splice site binding
0.48	GO:0003727	single-stranded RNA binding
0.47	GO:0042803	protein homodimerization activity
0.38	GO:1990446	U1 snRNP binding
0.32	GO:0003677	DNA binding

0.82	GO:0005685	U1 snRNP
0.79	GO:0000243	commitment complex
0.78	GO:0071010	prespliceosome
0.58	GO:0019013	viral nucleocapsid
0.50	GO:0015030	Cajal body

tr|Q1RLD4|Q1RLD4_CIOIN
Zinc finger protein (Fragment)
Search

0.10	Zinc finger protein (Fragment)

0.63	GO:0008270	zinc ion binding
0.51	GO:0003676	nucleic acid binding

0.61

GO:0005634

nucleus

tr|Q1RLD5|Q1RLD5_CIOIN
Zinc finger protein
Search

SLU7

0.50	Pre-mRNA-splicing factor SLU7

0.71	GO:0000375	RNA splicing, via transesterification reactions
0.64	GO:0034605	cellular response to heat
0.59	GO:0006397	mRNA processing
0.59	GO:0022618	ribonucleoprotein complex assembly
0.56	GO:0006886	intracellular protein transport
0.38	GO:0006369	termination of RNA polymerase II transcription
0.37	GO:0071166	ribonucleoprotein complex localization
0.37	GO:0051169	nuclear transport
0.37	GO:0031123	RNA 3'-end processing
0.37	GO:0051028	mRNA transport

0.84	GO:0000386	second spliceosomal transesterification activity
0.70	GO:0030628	pre-mRNA 3'-splice site binding
0.53	GO:0008270	zinc ion binding
0.35	GO:0005515	protein binding
0.33	GO:0016740	transferase activity

0.72	GO:0005681	spliceosomal complex
0.63	GO:0016607	nuclear speck
0.62	GO:0030532	small nuclear ribonucleoprotein complex
0.55	GO:0005829	cytosol
0.51	GO:1902494	catalytic complex
0.30	GO:0016020	membrane

0.33

EC:2

GO:0016740

tr|Q1RLE2|Q1RLE2_CIOIN
Zinc finger protein (Fragment)
Search

0.38	zinc finger protein 782

0.39	GO:1903506	regulation of nucleic acid-templated transcription
0.39	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.39	GO:0010468	regulation of gene expression
0.34	GO:0006338	chromatin remodeling
0.34	GO:0031150	sorocarp stalk development
0.34	GO:0071285	cellular response to lithium ion
0.33	GO:0032259	methylation
0.33	GO:0006351	transcription, DNA-templated
0.33	GO:0006281	DNA repair
0.32	GO:0010605	negative regulation of macromolecule metabolic process

0.51	GO:0003676	nucleic acid binding
0.39	GO:0046872	metal ion binding
0.33	GO:0003700	DNA binding transcription factor activity
0.33	GO:0008168	methyltransferase activity
0.33	GO:0016887	ATPase activity
0.32	GO:0005515	protein binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.38	GO:0005634	nucleus
0.34	GO:0033202	DNA helicase complex
0.33	GO:0000785	chromatin
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:1904949	ATPase complex
0.32	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.33

GO:0008168

tr|Q1RLE3|Q1RLE3_CIOIN
Zinc finger protein (Fragment)
Search

0.38	arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1

0.75	GO:0043547	positive regulation of GTPase activity
0.60	GO:0007165	signal transduction
0.42	GO:0051497	negative regulation of stress fiber assembly
0.42	GO:0051491	positive regulation of filopodium assembly
0.40	GO:0051270	regulation of cellular component movement
0.38	GO:0008360	regulation of cell shape
0.35	GO:0001921	positive regulation of receptor recycling
0.35	GO:0051056	regulation of small GTPase mediated signal transduction
0.33	GO:0030037	actin filament reorganization involved in cell cycle
0.33	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway

0.76	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.75	GO:0005096	GTPase activator activity
0.36	GO:0046872	metal ion binding
0.35	GO:0031702	type 1 angiotensin receptor binding
0.34	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.33	GO:0070412	R-SMAD binding
0.32	GO:0044212	transcription regulatory region DNA binding
0.32	GO:0008134	transcription factor binding
0.32	GO:0003700	DNA binding transcription factor activity

0.39	GO:0005829	cytosol
0.39	GO:0005794	Golgi apparatus
0.39	GO:0005654	nucleoplasm
0.36	GO:0005886	plasma membrane
0.34	GO:0031410	cytoplasmic vesicle
0.33	GO:0031984	organelle subcompartment
0.33	GO:0098588	bounding membrane of organelle
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:3.1.4.17

GO:0004114

tr|Q1RLE5|Q1RLE5_CIOIN
Zinc finger protein (Fragment)
Search

0.37	Zinc finger protein (Fragment)

0.43	GO:1903506	regulation of nucleic acid-templated transcription
0.43	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.43	GO:0010468	regulation of gene expression
0.34	GO:1902680	positive regulation of RNA biosynthetic process
0.34	GO:0006351	transcription, DNA-templated

0.51	GO:0003676	nucleic acid binding
0.44	GO:0046872	metal ion binding
0.34	GO:0003700	DNA binding transcription factor activity

0.40	GO:0005634	nucleus
0.32	GO:0005737	cytoplasm

tr|Q1RLE7|Q1RLE7_CIOIN
Zinc finger protein (Fragment)
Search

0.53	A disintegrin and metalloproteinase with thrombospondin motifs 8

0.61	GO:0006508	proteolysis
0.60	GO:0007229	integrin-mediated signaling pathway
0.48	GO:0042742	defense response to bacterium
0.40	GO:0044691	tooth eruption
0.36	GO:0030198	extracellular matrix organization
0.36	GO:0007507	heart development
0.36	GO:0090673	endothelial cell-matrix adhesion
0.35	GO:0045636	positive regulation of melanocyte differentiation
0.35	GO:0001542	ovulation from ovarian follicle
0.35	GO:1903671	negative regulation of sprouting angiogenesis

0.70	GO:0004222	metalloendopeptidase activity
0.55	GO:0008270	zinc ion binding
0.51	GO:0008201	heparin binding
0.51	GO:0050840	extracellular matrix binding
0.44	GO:0002020	protease binding
0.36	GO:0005178	integrin binding
0.36	GO:0009673	low-affinity phosphate transmembrane transporter activity
0.32	GO:0004867	serine-type endopeptidase inhibitor activity

0.64	GO:0005576	extracellular region
0.43	GO:0016607	nuclear speck
0.35	GO:0005783	endoplasmic reticulum
0.34	GO:0009986	cell surface
0.34	GO:0031410	cytoplasmic vesicle
0.30	GO:0016020	membrane

0.70

GO:0004222

tr|Q1RLE9|Q1RLE9_CIOIN
Zinc finger protein
Search

0.27	zinc finger protein ZF(C2H2)-82

0.43	GO:1903506	regulation of nucleic acid-templated transcription
0.43	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.43	GO:0010468	regulation of gene expression
0.39	GO:1902679	negative regulation of RNA biosynthetic process
0.38	GO:0051151	negative regulation of smooth muscle cell differentiation
0.37	GO:0043065	positive regulation of apoptotic process
0.36	GO:0022008	neurogenesis
0.36	GO:0032259	methylation
0.34	GO:0006351	transcription, DNA-templated
0.34	GO:1902680	positive regulation of RNA biosynthetic process

0.51	GO:0003676	nucleic acid binding
0.42	GO:0046872	metal ion binding
0.38	GO:0003700	DNA binding transcription factor activity
0.37	GO:0042803	protein homodimerization activity
0.36	GO:0008168	methyltransferase activity
0.33	GO:0003682	chromatin binding
0.32	GO:0008080	N-acetyltransferase activity
0.32	GO:0005524	ATP binding
0.32	GO:0140096	catalytic activity, acting on a protein

0.40	GO:0005634	nucleus
0.34	GO:0005876	spindle microtubule
0.32	GO:0043233	organelle lumen
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.36

GO:0008168

tr|Q1RLF0|Q1RLF0_CIOIN
Zinc finger protein
Search

0.49	Tumor necrosis factor receptor-associated factor 4

0.80	GO:0007250	activation of NF-kappaB-inducing kinase activity
0.77	GO:0046330	positive regulation of JNK cascade
0.72	GO:0042981	regulation of apoptotic process
0.45	GO:0090073	positive regulation of protein homodimerization activity
0.44	GO:0007585	respiratory gaseous exchange
0.43	GO:0030323	respiratory tube development
0.35	GO:0016567	protein ubiquitination
0.33	GO:0006468	protein phosphorylation
0.33	GO:0043043	peptide biosynthetic process
0.32	GO:0010467	gene expression

0.62	GO:0008270	zinc ion binding
0.45	GO:0031996	thioesterase binding
0.44	GO:0050699	WW domain binding
0.43	GO:0005164	tumor necrosis factor receptor binding
0.42	GO:0031625	ubiquitin protein ligase binding
0.42	GO:0019901	protein kinase binding
0.41	GO:0042802	identical protein binding
0.35	GO:0004842	ubiquitin-protein transferase activity
0.34	GO:0003676	nucleic acid binding
0.33	GO:0004672	protein kinase activity

0.43	GO:0005622	intracellular
0.36	GO:0043227	membrane-bounded organelle
0.33	GO:1990904	ribonucleoprotein complex
0.33	GO:0043228	non-membrane-bounded organelle
0.30	GO:0016020	membrane

0.35

GO:0004842

tr|Q1RLF1|Q1RLF1_CIOIN
Zinc finger protein (Fragment)
Search

0.37	Zinc finger protein 160

0.42	GO:1903506	regulation of nucleic acid-templated transcription
0.42	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.42	GO:0010468	regulation of gene expression
0.38	GO:0006351	transcription, DNA-templated
0.35	GO:1902679	negative regulation of RNA biosynthetic process
0.34	GO:0007283	spermatogenesis
0.34	GO:0007219	Notch signaling pathway
0.33	GO:0051321	meiotic cell cycle
0.33	GO:1902680	positive regulation of RNA biosynthetic process
0.33	GO:0000413	protein peptidyl-prolyl isomerization

0.51	GO:0003676	nucleic acid binding
0.42	GO:0046872	metal ion binding
0.40	GO:0003700	DNA binding transcription factor activity
0.34	GO:0003682	chromatin binding
0.33	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.32	GO:0004333	fumarate hydratase activity
0.32	GO:0005515	protein binding

0.42	GO:0005634	nucleus
0.33	GO:0005829	cytosol
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0045239	tricarboxylic acid cycle enzyme complex
0.32	GO:0005615	extracellular space
0.32	GO:0044446	intracellular organelle part

0.33	EC:5.2.1.8	GO:0003755
0.32	KEGG:R01082	GO:0004333

tr|Q1RLF5|Q1RLF5_CIOIN
Zinc finger protein
Search

0.27	zinc finger protein ZF(C2H2)-78

0.42	GO:1903506	regulation of nucleic acid-templated transcription
0.42	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.42	GO:0010468	regulation of gene expression
0.36	GO:1902679	negative regulation of RNA biosynthetic process
0.35	GO:0006366	transcription by RNA polymerase II
0.35	GO:1902680	positive regulation of RNA biosynthetic process
0.34	GO:0032259	methylation
0.34	GO:1990009	retinal cell apoptotic process
0.33	GO:1900112	regulation of histone H3-K9 trimethylation
0.33	GO:0051402	neuron apoptotic process

0.51	GO:0003676	nucleic acid binding
0.40	GO:0046872	metal ion binding
0.40	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.34	GO:0008168	methyltransferase activity
0.34	GO:0005166	neurotrophin p75 receptor binding
0.33	GO:0003682	chromatin binding

0.40	GO:0005634	nucleus
0.36	GO:0045111	intermediate filament cytoskeleton
0.35	GO:0031974	membrane-enclosed lumen
0.35	GO:0005829	cytosol
0.34	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.34

GO:0008168

tr|Q1RLF7|Q1RLF7_CIOIN
Zinc finger protein
Search

0.27	zinc finger protein ZF(C2H2)-75

0.46	GO:1903506	regulation of nucleic acid-templated transcription
0.46	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.45	GO:0010468	regulation of gene expression
0.36	GO:1902679	negative regulation of RNA biosynthetic process
0.36	GO:0006351	transcription, DNA-templated
0.33	GO:0046073	dTMP metabolic process
0.33	GO:0009177	pyrimidine deoxyribonucleoside monophosphate biosynthetic process
0.33	GO:0009221	pyrimidine deoxyribonucleotide biosynthetic process
0.32	GO:0032259	methylation

0.51	GO:0003676	nucleic acid binding
0.45	GO:0046872	metal ion binding
0.40	GO:0003700	DNA binding transcription factor activity
0.36	GO:0005515	protein binding
0.33	GO:0004799	thymidylate synthase activity

0.43	GO:0005634	nucleus
0.37	GO:0017053	transcriptional repressor complex
0.35	GO:0012505	endomembrane system
0.35	GO:0031967	organelle envelope
0.34	GO:0031090	organelle membrane
0.33	GO:0005829	cytosol
0.33	GO:0031974	membrane-enclosed lumen

0.33	EC:2.1.1.45	GO:0004799
0.33	KEGG:R02101	GO:0004799

tr|Q1RLF9|Q1RLF9_CIOIN
Transcription factor protein
Search

0.10	Transcription factor protein

0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression

0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity

0.61

GO:0005634

nucleus

tr|Q1RLG0|Q1RLG0_CIOIN
Zinc finger protein
Search

ZF(C2H2)-70

0.32	zinc finger protein ZF(C2H2)-70

0.47	GO:0051567	histone H3-K9 methylation
0.45	GO:1990823	response to leukemia inhibitory factor
0.45	GO:0016575	histone deacetylation
0.44	GO:0000122	negative regulation of transcription by RNA polymerase II
0.44	GO:0071345	cellular response to cytokine stimulus
0.43	GO:0000278	mitotic cell cycle
0.39	GO:0048702	embryonic neurocranium morphogenesis
0.38	GO:2000050	regulation of non-canonical Wnt signaling pathway
0.38	GO:0048703	embryonic viscerocranium morphogenesis
0.37	GO:0060828	regulation of canonical Wnt signaling pathway

0.56	GO:0000976	transcription regulatory region sequence-specific DNA binding
0.46	GO:0070491	repressing transcription factor binding
0.46	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.44	GO:0001012	RNA polymerase II regulatory region DNA binding
0.40	GO:0046872	metal ion binding
0.34	GO:0017034	Rap guanyl-nucleotide exchange factor activity
0.33	GO:0005543	phospholipid binding
0.33	GO:0005096	GTPase activator activity
0.33	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.33	GO:0008168	methyltransferase activity

0.44	GO:0016604	nuclear body
0.43	GO:0005730	nucleolus

0.33

GO:0016705

tr|Q1RLG2|Q1RLG2_CIOIN
Zinc finger protein
Search

0.47	zinc finger protein ZF(C2H2)-68

0.51

GO:0003676

nucleic acid binding

tr|Q1RLG4|Q1RLG4_CIOIN
tRNA-dihydrouridine(47) synthase [NAD(P)(+)]
Search

DUS3L

0.80	Dihydrouridine synthase 3-like (S. cerevisiae)

0.77	GO:0002943	tRNA dihydrouridine synthesis
0.53	GO:0055114	oxidation-reduction process

0.77	GO:0017150	tRNA dihydrouridine synthase activity
0.66	GO:0050660	flavin adenine dinucleotide binding
0.52	GO:0046872	metal ion binding
0.34	GO:0003723	RNA binding

tr|Q1RLG5|Q1RLG5_CIOIN
Zinc finger protein
Search

0.46	Transcription factor YY

0.45	GO:1902894	negative regulation of pri-miRNA transcription by RNA polymerase II
0.45	GO:0032688	negative regulation of interferon-beta production
0.45	GO:0010225	response to UV-C
0.44	GO:0034644	cellular response to UV
0.44	GO:0048593	camera-type eye morphogenesis
0.43	GO:0009952	anterior/posterior pattern specification
0.43	GO:0007283	spermatogenesis
0.42	GO:0000724	double-strand break repair via homologous recombination
0.42	GO:0010628	positive regulation of gene expression
0.41	GO:0006403	RNA localization

0.51	GO:0003676	nucleic acid binding
0.44	GO:0046332	SMAD binding
0.44	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.37	GO:0042826	histone deacetylase binding
0.35	GO:0003682	chromatin binding
0.34	GO:0003714	transcription corepressor activity
0.34	GO:0003713	transcription coactivator activity
0.33	GO:0046872	metal ion binding

0.44	GO:0031519	PcG protein complex
0.43	GO:0031011	Ino80 complex
0.41	GO:0005667	transcription factor complex
0.37	GO:0016363	nuclear matrix
0.35	GO:0005704	polytene chromosome band
0.35	GO:0005703	polytene chromosome puff
0.34	GO:0005654	nucleoplasm
0.33	GO:0005737	cytoplasm

tr|Q1RLG9|Q1RLG9_CIOIN
Zinc finger protein
Search

0.81	ARF GTPase-activating protein GIT1

0.76	GO:0043547	positive regulation of GTPase activity
0.45	GO:0048013	ephrin receptor signaling pathway
0.43	GO:0032465	regulation of cytokinesis
0.38	GO:0001771	immunological synapse formation
0.38	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.38	GO:0060996	dendritic spine development
0.37	GO:0032013	negative regulation of ARF protein signal transduction

0.76	GO:0005096	GTPase activator activity
0.49	GO:0046872	metal ion binding
0.42	GO:0032403	protein complex binding
0.34	GO:0031267	small GTPase binding
0.34	GO:0042803	protein homodimerization activity

0.46	GO:0005925	focal adhesion
0.42	GO:0005829	cytosol
0.34	GO:0043005	neuron projection
0.34	GO:0045202	synapse
0.30	GO:0016020	membrane

tr|Q1RLH3|Q1RLH3_CIOIN
Zinc finger protein
Search

CI-ZF(C2H2)-56

0.28	zinc finger protein Ci-ZF(C2H2)-56

0.49	GO:1903506	regulation of nucleic acid-templated transcription
0.49	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.48	GO:0010468	regulation of gene expression
0.37	GO:0001658	branching involved in ureteric bud morphogenesis
0.35	GO:1902679	negative regulation of RNA biosynthetic process
0.35	GO:0006311	meiotic gene conversion
0.35	GO:0010845	positive regulation of reciprocal meiotic recombination
0.35	GO:0051568	histone H3-K4 methylation
0.34	GO:0007283	spermatogenesis
0.34	GO:0006351	transcription, DNA-templated

0.51	GO:0003676	nucleic acid binding
0.46	GO:0046872	metal ion binding
0.40	GO:0003700	DNA binding transcription factor activity
0.35	GO:0042800	histone methyltransferase activity (H3-K4 specific)

0.42	GO:0005634	nucleus
0.35	GO:0031974	membrane-enclosed lumen
0.35	GO:0043232	intracellular non-membrane-bounded organelle
0.34	GO:0044446	intracellular organelle part

tr|Q1RLH5|Q1RLH5_CIOIN
Zinc finger protein
Search

0.27	zinc finger protein 55

0.61	GO:0006369	termination of RNA polymerase II transcription
0.58	GO:0006379	mRNA cleavage
0.58	GO:0006378	mRNA polyadenylation
0.54	GO:0006886	intracellular protein transport
0.34	GO:0000398	mRNA splicing, via spliceosome
0.34	GO:0006289	nucleotide-excision repair
0.33	GO:2001141	regulation of RNA biosynthetic process
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.55	GO:0000993	RNA polymerase II core binding
0.51	GO:0003729	mRNA binding
0.32	GO:0046872	metal ion binding

0.58	GO:0005849	mRNA cleavage factor complex
0.44	GO:0005739	mitochondrion
0.35	GO:0000439	core TFIIH complex
0.30	GO:0031224	intrinsic component of membrane

tr|Q1RLH6|Q1RLH6_CIOIN
Zinc finger protein (Fragment)
Search

0.61	lethal(3)malignant brain tumor-like protein 3

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.37	GO:0045652	regulation of megakaryocyte differentiation
0.36	GO:1901796	regulation of signal transduction by p53 class mediator
0.36	GO:0030097	hemopoiesis
0.36	GO:0007088	regulation of mitotic nuclear division
0.35	GO:0016569	covalent chromatin modification
0.35	GO:0051253	negative regulation of RNA metabolic process
0.35	GO:0010558	negative regulation of macromolecule biosynthetic process

0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.37	GO:0032093	SAM domain binding
0.37	GO:0031493	nucleosomal histone binding
0.36	GO:0140034	methylation-dependent protein binding
0.35	GO:0042802	identical protein binding
0.33	GO:0003723	RNA binding

0.61	GO:0005634	nucleus
0.35	GO:0000793	condensed chromosome
0.35	GO:0000785	chromatin
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0005886	plasma membrane

tr|Q1RLH9|Q1RLH9_CIOIN
Zinc finger protein
Search

0.30	Blimp-like zinc finger protein 2

0.53	GO:1990654	sebum secreting cell proliferation
0.52	GO:0033082	regulation of extrathymic T cell differentiation
0.51	GO:0051136	regulation of NK T cell differentiation
0.51	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway
0.51	GO:0060576	intestinal epithelial cell development
0.51	GO:0032823	regulation of natural killer cell differentiation
0.50	GO:0045579	positive regulation of B cell differentiation
0.50	GO:0030889	negative regulation of B cell proliferation
0.50	GO:0060707	trophoblast giant cell differentiation
0.50	GO:0060976	coronary vasculature development

0.51	GO:0003676	nucleic acid binding
0.50	GO:1990841	promoter-specific chromatin binding
0.49	GO:0042826	histone deacetylase binding
0.48	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.37	GO:0004672	protein kinase activity
0.35	GO:0030554	adenyl nucleotide binding
0.35	GO:0097367	carbohydrate derivative binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0008168	methyltransferase activity

0.41	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm
0.33	GO:0070013	intracellular organelle lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.34

GO:0008168

tr|Q1RLI2|Q1RLI2_CIOIN
Zinc finger protein (Fragment)
Search

0.38	zinc finger protein basonuclin-1

0.39	GO:0043586	tongue development
0.39	GO:0003416	endochondral bone growth
0.38	GO:0060021	palate development
0.38	GO:0009888	tissue development
0.37	GO:0007283	spermatogenesis
0.37	GO:0008284	positive regulation of cell proliferation
0.36	GO:0030154	cell differentiation
0.36	GO:0006351	transcription, DNA-templated
0.35	GO:1903506	regulation of nucleic acid-templated transcription
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.51	GO:0003676	nucleic acid binding
0.35	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding
0.33	GO:0003700	DNA binding transcription factor activity

0.40	GO:0005654	nucleoplasm
0.33	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|Q1RLI4|Q1RLI4_CIOIN
Zinc finger protein
Search

0.10	Zinc finger protein

0.76	GO:0043547	positive regulation of GTPase activity
0.38	GO:0010051	xylem and phloem pattern formation
0.37	GO:0010087	phloem or xylem histogenesis
0.37	GO:0009965	leaf morphogenesis
0.36	GO:0009733	response to auxin
0.35	GO:0006897	endocytosis

0.76	GO:0005096	GTPase activator activity
0.52	GO:0046872	metal ion binding
0.44	GO:1902936	phosphatidylinositol bisphosphate binding
0.35	GO:0003924	GTPase activity
0.35	GO:0032550	purine ribonucleoside binding
0.35	GO:0032561	guanyl ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0003676	nucleic acid binding

0.42	GO:0005737	cytoplasm
0.35	GO:0097708	intracellular vesicle
0.35	GO:0012505	endomembrane system
0.33	GO:0005886	plasma membrane

tr|Q1RLI5|Q1RLI5_CIOIN
Zinc finger protein
Search

CI-ZF(C2H2)-42

0.27	zinc finger protein Ci-ZF(C2H2)-42

0.43	GO:1903506	regulation of nucleic acid-templated transcription
0.43	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.43	GO:0010468	regulation of gene expression
0.34	GO:1900111	positive regulation of histone H3-K9 dimethylation
0.33	GO:0006351	transcription, DNA-templated
0.33	GO:0016573	histone acetylation

0.51	GO:0003676	nucleic acid binding
0.40	GO:0046872	metal ion binding
0.39	GO:0003700	DNA binding transcription factor activity
0.33	GO:0004402	histone acetyltransferase activity

0.37	GO:0005622	intracellular
0.34	GO:0043227	membrane-bounded organelle

0.33

GO:0004402

tr|Q1RLI8|Q1RLI8_CIOIN
Zinc finger protein
Search

0.42	zinc finger protein 38

0.54	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding

tr|Q1RLI9|Q1RLI9_CIOIN
Zinc finger protein
Search

ZF(BBOX/RING)-1

0.36	zinc finger protein ZF(Bbox/RING)-1

0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression
0.34	GO:0007165	signal transduction
0.33	GO:0016310	phosphorylation
0.33	GO:0006508	proteolysis

0.61	GO:0008270	zinc ion binding
0.34	GO:0016301	kinase activity
0.34	GO:0003676	nucleic acid binding
0.33	GO:0008233	peptidase activity

0.44	GO:0005622	intracellular
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:3.4

GO:0008233

tr|Q1RPU5|Q1RPU5_CIOIN
Zinc finger protein
Search

RFWD2

0.94	Ring finger and WD repeat domain 2

0.85	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.83	GO:0010212	response to ionizing radiation
0.78	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.73	GO:0016567	protein ubiquitination

0.76

GO:0061630

ubiquitin protein ligase activity

0.85	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex
0.42	GO:0000139	Golgi membrane

tr|Q1RPU6|Q1RPU6_CIOIN
DNA-directed RNA polymerase subunit
Search

POLR3K

0.51	DNA-directed RNA polymerase subunit

0.81	GO:0006379	mRNA cleavage
0.58	GO:0006351	transcription, DNA-templated
0.47	GO:0061484	hematopoietic stem cell homeostasis
0.37	GO:0042779	tRNA 3'-trailer cleavage
0.36	GO:0060255	regulation of macromolecule metabolic process
0.36	GO:0045087	innate immune response
0.36	GO:0051607	defense response to virus
0.35	GO:0080090	regulation of primary metabolic process
0.35	GO:0031323	regulation of cellular metabolic process
0.35	GO:0009889	regulation of biosynthetic process

0.70	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.63	GO:0008270	zinc ion binding
0.51	GO:0003676	nucleic acid binding
0.34	GO:0051537	2 iron, 2 sulfur cluster binding
0.33	GO:0017171	serine hydrolase activity
0.33	GO:0070011	peptidase activity, acting on L-amino acid peptides

0.69	GO:0005730	nucleolus
0.49	GO:0005666	DNA-directed RNA polymerase III complex
0.34	GO:0042720	mitochondrial inner membrane peptidase complex
0.33	GO:0005829	cytosol

0.70

EC:2.7.7.6

GO:0003899

tr|Q1RPV0|Q1RPV0_CIOIN
Zinc finger protein
Search

RSPRY1

0.50	Novel protein containing SPRY domain-containing SOCS box protein SSB-3

0.41	GO:0043043	peptide biosynthetic process
0.40	GO:0044267	cellular protein metabolic process
0.40	GO:0010467	gene expression
0.38	GO:0009059	macromolecule biosynthetic process
0.36	GO:0016311	dephosphorylation
0.35	GO:0006399	tRNA metabolic process
0.35	GO:0036211	protein modification process

0.53	GO:0046872	metal ion binding
0.43	GO:0003735	structural constituent of ribosome
0.38	GO:0003972	RNA ligase (ATP) activity
0.36	GO:0004721	phosphoprotein phosphatase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.43	GO:0005576	extracellular region
0.42	GO:0005840	ribosome
0.39	GO:0072669	tRNA-splicing ligase complex
0.37	GO:0005581	collagen trimer
0.30	GO:0016020	membrane

0.38

EC:6.5.1.3

GO:0003972

tr|Q1RPW1|Q1RPW1_CIOIN
Palmitoyltransferase
Search

ZDHHC20

0.53	Palmitoyltransferase

0.48	GO:0018345	protein palmitoylation
0.37	GO:0016188	synaptic vesicle maturation
0.32	GO:0045184	establishment of protein localization

0.80

GO:0019706

protein-cysteine S-palmitoyltransferase activity

0.40	GO:0005886	plasma membrane
0.33	GO:0005794	Golgi apparatus
0.30	GO:0044425	membrane part

0.80

EC:2.3.1.225

GO:0019706

tr|Q1RPW7|Q1RPW7_CIOIN
Zinc finger protein
Search

DDX41

0.50	ATP-dependent RNA helicase abstrakt

0.50	GO:0035458	cellular response to interferon-beta
0.47	GO:0008283	cell proliferation
0.47	GO:0010501	RNA secondary structure unwinding
0.46	GO:0051607	defense response to virus
0.46	GO:0000398	mRNA splicing, via spliceosome
0.45	GO:0045944	positive regulation of transcription by RNA polymerase II
0.44	GO:0030154	cell differentiation
0.34	GO:0032481	positive regulation of type I interferon production
0.34	GO:0006915	apoptotic process

0.57	GO:0004386	helicase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0003676	nucleic acid binding
0.50	GO:0008270	zinc ion binding
0.44	GO:0008186	RNA-dependent ATPase activity
0.40	GO:0140098	catalytic activity, acting on RNA
0.34	GO:0005515	protein binding

0.51	GO:0071013	catalytic step 2 spliceosome
0.44	GO:0005783	endoplasmic reticulum
0.43	GO:0005730	nucleolus
0.34	GO:0071011	precatalytic spliceosome
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|Q1RPW9|Q1RPW9_CIOIN
Zinc finger protein
Search

WDFY2

0.93	WD repeat and FYVE domain-containing protein 2

0.55	GO:0045600	positive regulation of fat cell differentiation
0.51	GO:0001934	positive regulation of protein phosphorylation
0.42	GO:0034141	positive regulation of toll-like receptor 3 signaling pathway
0.42	GO:0034145	positive regulation of toll-like receptor 4 signaling pathway

0.53	GO:0046872	metal ion binding
0.41	GO:0005545	1-phosphatidylinositol binding
0.34	GO:0005515	protein binding

0.54	GO:0005769	early endosome
0.38	GO:0005829	cytosol
0.36	GO:0005634	nucleus

tr|Q1RPX1|Q1RPX1_CIOIN
Histone acetyltransferase
Search

KAT7

0.55	Histone acetyltransferase

0.78	GO:0016573	histone acetylation
0.58	GO:0072739	response to anisomycin
0.58	GO:0072720	response to dithiothreitol
0.57	GO:0072708	response to sorbitol
0.57	GO:0072716	response to actinomycin D
0.57	GO:0006355	regulation of transcription, DNA-templated
0.57	GO:0090240	positive regulation of histone H4 acetylation
0.56	GO:0072710	response to hydroxyurea
0.53	GO:1900182	positive regulation of protein localization to nucleus
0.53	GO:0031098	stress-activated protein kinase signaling cascade

0.80	GO:0004402	histone acetyltransferase activity
0.62	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.51	GO:0003688	DNA replication origin binding
0.50	GO:0044212	transcription regulatory region DNA binding
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.50	GO:0031248	protein acetyltransferase complex
0.47	GO:0005829	cytosol
0.46	GO:0031974	membrane-enclosed lumen
0.42	GO:0044446	intracellular organelle part
0.34	GO:0043232	intracellular non-membrane-bounded organelle

0.80

GO:0004402

tr|Q1RPX5|Q1RPX5_CIOIN
Zinc finger protein
Search

0.32	zinc finger protein

0.60	GO:0061158	3'-UTR-mediated mRNA destabilization
0.40	GO:1903339	negative regulation of cell wall organization or biogenesis
0.39	GO:0051511	negative regulation of unidimensional cell growth
0.39	GO:2000652	regulation of secondary cell wall biogenesis
0.36	GO:0045893	positive regulation of transcription, DNA-templated

0.57	GO:0003730	mRNA 3'-UTR binding
0.54	GO:0046872	metal ion binding

0.50

GO:0005829

cytosol

tr|Q1RPY5|Q1RPY5_CIOIN
Zinc finger protein
Search

0.27	zinc finger protein

0.75	GO:0008063	Toll signaling pathway
0.74	GO:0033209	tumor necrosis factor-mediated signaling pathway
0.74	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.74	GO:0050688	regulation of defense response to virus
0.71	GO:0042981	regulation of apoptotic process
0.69	GO:0001817	regulation of cytokine production
0.68	GO:0045087	innate immune response
0.49	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling
0.49	GO:0016567	protein ubiquitination
0.49	GO:0002224	toll-like receptor signaling pathway

0.78	GO:0005164	tumor necrosis factor receptor binding
0.62	GO:0008270	zinc ion binding
0.52	GO:0031996	thioesterase binding
0.49	GO:0019903	protein phosphatase binding
0.49	GO:0004842	ubiquitin-protein transferase activity
0.48	GO:0031625	ubiquitin protein ligase binding
0.47	GO:0019901	protein kinase binding
0.34	GO:0042802	identical protein binding
0.34	GO:0003677	DNA binding
0.33	GO:0004871	signal transducer activity

0.51	GO:0035631	CD40 receptor complex
0.46	GO:0009898	cytoplasmic side of plasma membrane
0.35	GO:0005813	centrosome
0.35	GO:0005829	cytosol
0.35	GO:0005768	endosome
0.32	GO:0005739	mitochondrion

0.32	EC:3.6.1.3	GO:0016887
0.49	KEGG:R03876	GO:0004842

tr|Q1RPZ1|Q1RPZ1_CIOIN
Zinc finger protein
Search

0.27	zinc finger protein

0.47	GO:1903506	regulation of nucleic acid-templated transcription
0.47	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.46	GO:0010468	regulation of gene expression
0.36	GO:1902679	negative regulation of RNA biosynthetic process
0.34	GO:0006351	transcription, DNA-templated

0.51	GO:0003676	nucleic acid binding
0.44	GO:0046872	metal ion binding
0.42	GO:0046983	protein dimerization activity
0.40	GO:0003700	DNA binding transcription factor activity

0.39	GO:0005622	intracellular
0.36	GO:0043227	membrane-bounded organelle
0.34	GO:0043234	protein complex
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0044422	organelle part
0.30	GO:0031224	intrinsic component of membrane

tr|Q1RPZ2|Q1RPZ2_CIOIN
Zinc finger protein
Search

SF3A2

0.48	Spliceosome-associated protein 62

0.44	GO:0000245	spliceosomal complex assembly
0.36	GO:0010976	positive regulation of neuron projection development
0.34	GO:0046579	positive regulation of Ras protein signal transduction
0.34	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.33	GO:0043043	peptide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0009059	macromolecule biosynthetic process

0.63	GO:0008270	zinc ion binding
0.51	GO:0003676	nucleic acid binding
0.34	GO:0005199	structural constituent of cell wall
0.33	GO:0005515	protein binding
0.33	GO:0003735	structural constituent of ribosome
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005634	nucleus
0.43	GO:0120114	Sm-like protein family complex
0.41	GO:1902494	catalytic complex
0.41	GO:0030529	intracellular ribonucleoprotein complex
0.40	GO:0044446	intracellular organelle part
0.34	GO:0031974	membrane-enclosed lumen
0.32	GO:0043232	intracellular non-membrane-bounded organelle
0.32	GO:0044444	cytoplasmic part

tr|Q1RPZ3|Q1RPZ3_CIOIN
Zinc finger protein
Search

ADAP1

0.50	Arf-GAP with dual PH domain-containing protein 1

0.76	GO:0043547	positive regulation of GTPase activity
0.37	GO:0007507	heart development
0.35	GO:0048016	inositol phosphate-mediated signaling
0.35	GO:0007368	determination of left/right symmetry
0.34	GO:0048562	embryonic organ morphogenesis
0.34	GO:0060562	epithelial tube morphogenesis
0.34	GO:0007186	G-protein coupled receptor signaling pathway

0.82	GO:1902936	phosphatidylinositol bisphosphate binding
0.76	GO:0005096	GTPase activator activity
0.51	GO:0046872	metal ion binding
0.39	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.38	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding
0.34	GO:0004930	G-protein coupled receptor activity
0.32	GO:0003924	GTPase activity
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0019001	guanyl nucleotide binding
0.31	GO:0032555	purine ribonucleotide binding

0.39	GO:0005829	cytosol
0.38	GO:0005634	nucleus
0.37	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|Q1RQ01|Q1RQ01_CIOIN
Zinc finger protein
Search

0.38	F-box only protein 11

0.73	GO:0016567	protein ubiquitination
0.48	GO:0035246	peptidyl-arginine N-methylation
0.47	GO:0007605	sensory perception of sound
0.33	GO:0043687	post-translational protein modification
0.33	GO:0006511	ubiquitin-dependent protein catabolic process
0.32	GO:0006351	transcription, DNA-templated
0.32	GO:0006355	regulation of transcription, DNA-templated

0.61	GO:0008270	zinc ion binding
0.48	GO:0016274	protein-arginine N-methyltransferase activity
0.44	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0005515	protein binding
0.32	GO:0003677	DNA binding

0.76	GO:0000151	ubiquitin ligase complex
0.44	GO:0005730	nucleolus
0.43	GO:0005829	cytosol
0.34	GO:0005694	chromosome

0.48	EC:2.1.1	GO:0016274
0.44	KEGG:R03876	GO:0004842

tr|Q1RQ07|Q1RQ07_CIOIN
Zinc finger protein (Fragment)
Search

BMPER

0.65	BMP binding endothelial regulator

0.76	GO:0030510	regulation of BMP signaling pathway
0.74	GO:0048839	inner ear development
0.73	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis
0.73	GO:0042118	endothelial cell activation
0.70	GO:0035295	tube development
0.69	GO:0060393	regulation of pathway-restricted SMAD protein phosphorylation
0.69	GO:0060429	epithelium development
0.69	GO:0001823	mesonephros development
0.68	GO:0090101	negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
0.68	GO:0010594	regulation of endothelial cell migration

0.55	GO:0050840	extracellular matrix binding
0.42	GO:0005515	protein binding
0.33	GO:0005509	calcium ion binding
0.32	GO:0004867	serine-type endopeptidase inhibitor activity
0.31	GO:0016491	oxidoreductase activity

0.67	GO:0005615	extracellular space
0.51	GO:0005578	proteinaceous extracellular matrix
0.30	GO:0016020	membrane

0.31

EC:1

GO:0016491

tr|Q1RQ09|Q1RQ09_CIOIN
Zinc finger protein
Search

0.27	zinc finger protein

0.45	GO:2001141	regulation of RNA biosynthetic process
0.45	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.44	GO:0010468	regulation of gene expression
0.44	GO:0007398	ectoderm development
0.44	GO:0071158	positive regulation of cell cycle arrest
0.44	GO:0001702	gastrulation with mouth forming second
0.44	GO:1903146	regulation of autophagy of mitochondrion
0.43	GO:1903955	positive regulation of protein targeting to mitochondrion
0.42	GO:0008285	negative regulation of cell proliferation
0.41	GO:0006366	transcription by RNA polymerase II

0.51	GO:0003676	nucleic acid binding
0.44	GO:0001223	transcription coactivator binding
0.42	GO:0046872	metal ion binding
0.42	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.34	GO:0005540	hyaluronic acid binding
0.34	GO:0005272	sodium channel activity
0.32	GO:0008168	methyltransferase activity

0.40	GO:0032993	protein-DNA complex
0.40	GO:0005634	nucleus
0.37	GO:0043234	protein complex
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.32	GO:0005886	plasma membrane
0.32	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.32

GO:0008168

tr|Q1RQ12|Q1RQ12_CIOIN
Zinc finger protein
Search

0.37	Zinc finger FYVE domain-containing protein 21

0.41	GO:0016482	cytosolic transport
0.41	GO:0035335	peptidyl-tyrosine dephosphorylation
0.41	GO:0016197	endosomal transport
0.40	GO:0006458	'de novo' protein folding
0.40	GO:0061077	chaperone-mediated protein folding
0.40	GO:0046854	phosphatidylinositol phosphorylation
0.39	GO:0016192	vesicle-mediated transport
0.38	GO:0035023	regulation of Rho protein signal transduction
0.36	GO:0065009	regulation of molecular function
0.36	GO:0000011	vacuole inheritance

0.54	GO:0046872	metal ion binding
0.43	GO:0000285	1-phosphatidylinositol-3-phosphate 5-kinase activity
0.41	GO:0044183	protein binding involved in protein folding
0.41	GO:0004725	protein tyrosine phosphatase activity
0.39	GO:0017016	Ras GTPase binding
0.38	GO:0051082	unfolded protein binding
0.38	GO:0005085	guanyl-nucleotide exchange factor activity
0.34	GO:0032266	phosphatidylinositol-3-phosphate binding
0.33	GO:0015144	carbohydrate transmembrane transporter activity
0.33	GO:0032559	adenyl ribonucleotide binding

0.41	GO:0010008	endosome membrane
0.39	GO:0005829	cytosol
0.35	GO:0098562	cytoplasmic side of membrane
0.30	GO:0016021	integral component of membrane

0.43	EC:2.7.1.150	GO:0000285
0.43	KEGG:R05802	GO:0000285

tr|Q256Z9|Q256Z9_CIOIN
Hexosyltransferase
Search

B3GALT6

0.57	Hexosyltransferase

0.72	GO:0006486	protein glycosylation
0.44	GO:0006024	glycosaminoglycan biosynthetic process

0.78	GO:0008378	galactosyltransferase activity
0.46	GO:0008194	UDP-glycosyltransferase activity
0.33	GO:0030246	carbohydrate binding

0.72	GO:0000139	Golgi membrane
0.50	GO:0005797	Golgi medial cisterna
0.30	GO:0031224	intrinsic component of membrane

0.78

GO:0008378

tr|Q2AC14|Q2AC14_CIOIN
GnRH-like hexadecapeptide
Search

LOC664635

0.95	GnRH-like hexadecapeptide precursor

0.76	GO:0010469	regulation of receptor activity
0.70	GO:0007275	multicellular organism development

0.79

GO:0005179

hormone activity

0.66

GO:0005576

extracellular region

tr|Q2PEE1|Q2PEE1_CIOIN
Dynein light chain 6
Search

DYNLL2

0.76	Dynein light chain

0.72	GO:0007017	microtubule-based process
0.50	GO:2000580	regulation of ATP-dependent microtubule motor activity, plus-end-directed
0.50	GO:2000576	positive regulation of microtubule motor activity
0.48	GO:0030705	cytoskeleton-dependent intracellular transport
0.47	GO:0060271	cilium assembly
0.47	GO:0032781	positive regulation of ATPase activity
0.44	GO:0006928	movement of cell or subcellular component
0.39	GO:1902857	positive regulation of non-motile cilium assembly
0.38	GO:0031503	protein complex localization
0.38	GO:0042326	negative regulation of phosphorylation

0.49	GO:0045505	dynein intermediate chain binding
0.49	GO:0051959	dynein light intermediate chain binding
0.49	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed
0.44	GO:0008092	cytoskeletal protein binding
0.38	GO:0008022	protein C-terminus binding
0.37	GO:0097110	scaffold protein binding
0.37	GO:0019904	protein domain specific binding
0.36	GO:0046983	protein dimerization activity
0.36	GO:0042802	identical protein binding
0.35	GO:0030235	nitric-oxide synthase regulator activity

0.79	GO:0030286	dynein complex
0.50	GO:0031475	myosin V complex
0.47	GO:0005813	centrosome
0.41	GO:0005929	cilium
0.39	GO:0072686	mitotic spindle
0.39	GO:0000776	kinetochore
0.39	GO:0008180	COP9 signalosome
0.38	GO:0005874	microtubule
0.37	GO:0043186	P granule
0.36	GO:0005829	cytosol

0.49

EC:3.6.4.4

GO:0008574

tr|Q2PEE2|Q2PEE2_CIOIN
Tctex1-related dynein light chain
Search

DYNLT1

0.92	Dynein molecular motor protein light chain

0.79	GO:0019060	intracellular transport of viral protein in host cell
0.60	GO:0008090	retrograde axonal transport
0.57	GO:0008340	determination of adult lifespan
0.57	GO:0007286	spermatid development
0.45	GO:0000132	establishment of mitotic spindle orientation
0.45	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.45	GO:0050768	negative regulation of neurogenesis
0.45	GO:1905709	negative regulation of membrane permeability
0.44	GO:0035022	positive regulation of Rac protein signal transduction
0.43	GO:0046902	regulation of mitochondrial membrane permeability

0.72	GO:0042802	identical protein binding
0.59	GO:0051959	dynein light intermediate chain binding
0.59	GO:0097718	disordered domain specific binding
0.58	GO:0045505	dynein intermediate chain binding
0.49	GO:0046983	protein dimerization activity
0.44	GO:0003774	motor activity
0.42	GO:0008022	protein C-terminus binding
0.35	GO:0042623	ATPase activity, coupled

0.77	GO:0030286	dynein complex
0.74	GO:0005881	cytoplasmic microtubule
0.70	GO:0099503	secretory vesicle
0.59	GO:0033267	axon part
0.58	GO:0120111	neuron projection cytoplasm
0.57	GO:0044216	other organism cell
0.57	GO:0018995	host
0.43	GO:0005819	spindle
0.43	GO:0030426	growth cone
0.42	GO:0030027	lamellipodium

tr|Q2PEE5|Q2PEE5_CIOIN
DC2-related axonemal dynein intermediate chain 5
Search

0.69	Coiled-coil domain-containing protein 63

0.78	GO:0036158	outer dynein arm assembly
0.74	GO:0003341	cilium movement

0.38

GO:0005509

calcium ion binding

0.80	GO:0005930	axoneme
0.41	GO:0031514	motile cilium

tr|Q32TF6|Q32TF6_CIOIN
EFHC2
Search

EFHC2

0.94	EF-hand domain containing 2

0.59	GO:1990823	response to leukemia inhibitory factor
0.56	GO:0071345	cellular response to cytokine stimulus

0.65	GO:0005509	calcium ion binding
0.35	GO:0005515	protein binding

0.36	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane
0.30	GO:0005623	cell

tr|Q3MQ22|Q3MQ22_CIOIN
Autophagy protein 5
Search

ATG5

0.65	Autophagy protein 5

0.77	GO:0006914	autophagy
0.51	GO:0007033	vacuole organization
0.50	GO:0006501	C-terminal protein lipidation
0.49	GO:0061726	mitochondrion disassembly
0.48	GO:0006995	cellular response to nitrogen starvation
0.48	GO:0043416	regulation of skeletal muscle tissue regeneration
0.47	GO:0070925	organelle assembly
0.47	GO:0007507	heart development
0.43	GO:0007399	nervous system development
0.41	GO:2000619	negative regulation of histone H4-K16 acetylation

0.50

GO:0019776

Atg8 ligase activity

0.84	GO:0034045	phagophore assembly site membrane
0.50	GO:0034274	Atg12-Atg5-Atg16 complex
0.39	GO:0005776	autophagosome
0.39	GO:0044233	ER-mitochondrion membrane contact site
0.39	GO:0005930	axoneme
0.30	GO:0016021	integral component of membrane

tr|Q4H2I7|Q4H2I7_CIOIN
Zinc finger protein
Search

0.42	Zinc finger protein 207 a

0.43	GO:0090307	mitotic spindle assembly
0.43	GO:0008608	attachment of spindle microtubules to kinetochore
0.43	GO:0007094	mitotic spindle assembly checkpoint
0.40	GO:0050821	protein stabilization
0.40	GO:0000070	mitotic sister chromatid segregation
0.35	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.34	GO:0001578	microtubule bundle formation
0.34	GO:0046785	microtubule polymerization
0.34	GO:0009405	pathogenesis
0.33	GO:0051301	cell division

0.51	GO:0003676	nucleic acid binding
0.41	GO:0008017	microtubule binding
0.40	GO:0008201	heparin binding
0.32	GO:0046872	metal ion binding
0.32	GO:0005375	copper ion transmembrane transporter activity
0.30	GO:0003824	catalytic activity

0.45	GO:1990047	spindle matrix
0.42	GO:0000776	kinetochore
0.38	GO:0005634	nucleus
0.37	GO:0031974	membrane-enclosed lumen
0.34	GO:0000779	condensed chromosome, centromeric region
0.34	GO:0005819	spindle
0.34	GO:0005874	microtubule
0.32	GO:1902494	catalytic complex
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.32	GO:0005737	cytoplasm

tr|Q4H2J7|Q4H2J7_CIOIN
Zinc finger protein
Search

SP9

0.52	Transcription factor Sp9

0.44	GO:0035118	embryonic pectoral fin morphogenesis
0.44	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway
0.42	GO:0030326	embryonic limb morphogenesis

0.51

GO:0003676

nucleic acid binding

tr|Q4H2L1|Q4H2L1_CIOIN
Zinc finger protein
Search

0.30	Zinc finger protein

0.39	GO:0016348	imaginal disc-derived leg joint morphogenesis
0.39	GO:0048617	embryonic foregut morphogenesis
0.39	GO:0007362	terminal region determination
0.39	GO:1903506	regulation of nucleic acid-templated transcription
0.39	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.39	GO:0010468	regulation of gene expression
0.38	GO:0048619	embryonic hindgut morphogenesis
0.38	GO:0035220	wing disc development
0.35	GO:0007366	periodic partitioning by pair rule gene
0.35	GO:1902680	positive regulation of RNA biosynthetic process

0.51	GO:0003676	nucleic acid binding
0.38	GO:0046872	metal ion binding
0.36	GO:0003700	DNA binding transcription factor activity
0.34	GO:0016433	rRNA (adenine) methyltransferase activity

0.36	GO:0005634	nucleus
0.35	GO:0031974	membrane-enclosed lumen
0.35	GO:0015630	microtubule cytoskeleton
0.34	GO:0044446	intracellular organelle part
0.34	GO:0005794	Golgi apparatus
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0016433

tr|Q4H2M1|Q4H2M1_CIOIN
Transcription factor protein
Search

0.52	transcription factor protein

0.72	GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response
0.61	GO:0006366	transcription by RNA polymerase II

0.62	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity

0.51

GO:0005634

nucleus

tr|Q4H2M5|Q4H2M5_CIOIN
Protein Wnt
Search

0.77	GO:0016055	Wnt signaling pathway
0.70	GO:0007275	multicellular organism development
0.50	GO:0090403	oxidative stress-induced premature senescence
0.50	GO:0043616	keratinocyte proliferation
0.49	GO:0030154	cell differentiation
0.49	GO:0090399	replicative senescence
0.49	GO:0060429	epithelium development
0.48	GO:0046849	bone remodeling
0.48	GO:0060548	negative regulation of cell death
0.48	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling

0.73	GO:0005102	receptor binding
0.39	GO:0044212	transcription regulatory region DNA binding
0.39	GO:0030295	protein kinase activator activity
0.38	GO:0005096	GTPase activator activity
0.36	GO:0030545	receptor regulator activity
0.35	GO:0003714	transcription corepressor activity
0.34	GO:0019904	protein domain specific binding
0.34	GO:0003785	actin monomer binding
0.32	GO:0005328	neurotransmitter:sodium symporter activity
0.32	GO:0004871	signal transducer activity

0.75	GO:0005578	proteinaceous extracellular matrix
0.48	GO:0005615	extracellular space
0.39	GO:0009986	cell surface
0.37	GO:0005737	cytoplasm
0.33	GO:0012505	endomembrane system
0.32	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016020	membrane

tr|Q4H2N1|Q4H2N1_CIOIN
Transcription factor protein
Search

0.77	Upstream stimulatory factor

0.50	GO:0000432	positive regulation of transcription from RNA polymerase II promoter by glucose
0.48	GO:0007595	lactation
0.46	GO:0055088	lipid homeostasis
0.44	GO:0006366	transcription by RNA polymerase II
0.35	GO:0006265	DNA topological change
0.35	GO:0019086	late viral transcription
0.32	GO:0055114	oxidation-reduction process

0.68	GO:0046983	protein dimerization activity
0.48	GO:0043425	bHLH transcription factor binding
0.47	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.44	GO:0042802	identical protein binding
0.41	GO:0043565	sequence-specific DNA binding
0.35	GO:0061505	DNA topoisomerase II activity
0.34	GO:0008094	DNA-dependent ATPase activity
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.34	GO:0001012	RNA polymerase II regulatory region DNA binding
0.33	GO:0003690	double-stranded DNA binding

0.42

GO:0005654

nucleoplasm

0.34

EC:1.3.1.74

GO:0032440

tr|Q4H2N7|Q4H2N7_CIOIN
Transcription factor protein
Search

0.45	homeobox transcription factor TTF1

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.52	GO:0021536	diencephalon development
0.51	GO:0021761	limbic system development
0.49	GO:0010719	negative regulation of epithelial to mesenchymal transition
0.49	GO:0060486	Clara cell differentiation
0.49	GO:0060441	epithelial tube branching involved in lung morphogenesis
0.49	GO:0030878	thyroid gland development
0.49	GO:0048857	neural nucleus development

0.65	GO:0043565	sequence-specific DNA binding
0.50	GO:0044213	intronic transcription regulatory region DNA binding
0.47	GO:0001047	core promoter binding
0.47	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.46	GO:0001012	RNA polymerase II regulatory region DNA binding
0.44	GO:0003690	double-stranded DNA binding
0.44	GO:0019899	enzyme binding
0.35	GO:0008134	transcription factor binding
0.34	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.34	GO:0042803	protein homodimerization activity

0.61	GO:0005634	nucleus
0.44	GO:0005667	transcription factor complex
0.37	GO:0070013	intracellular organelle lumen
0.35	GO:0044446	intracellular organelle part
0.32	GO:0005576	extracellular region
0.30	GO:0016020	membrane

tr|Q4H2P0|Q4H2P0_CIOIN
Transcription factor protein
Search

MLX

0.77	Max protein X

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.45	GO:0051254	positive regulation of RNA metabolic process
0.45	GO:0010557	positive regulation of macromolecule biosynthetic process
0.45	GO:0031328	positive regulation of cellular biosynthetic process
0.45	GO:0051253	negative regulation of RNA metabolic process
0.45	GO:0010558	negative regulation of macromolecule biosynthetic process
0.45	GO:0031327	negative regulation of cellular biosynthetic process
0.42	GO:0008343	adult feeding behavior

0.72	GO:0008134	transcription factor binding
0.68	GO:0046983	protein dimerization activity
0.49	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.47	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.45	GO:0042802	identical protein binding
0.36	GO:0004140	dephospho-CoA kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0016491	oxidoreductase activity

0.48	GO:0031965	nuclear membrane
0.45	GO:0005654	nucleoplasm
0.44	GO:0005829	cytosol
0.33	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.36	EC:2.7.1.24	GO:0004140
0.36	KEGG:R00130	GO:0004140

tr|Q4H2P6|Q4H2P6_CIOIN
Transforming growth factor beta superfamily signaling ligand
Search

TGFBETA-NA2

0.86	Transforming growth factor beta superfamily signaling ligand

0.76	GO:0010469	regulation of receptor activity
0.59	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
0.59	GO:0060395	SMAD protein signal transduction
0.58	GO:0030509	BMP signaling pathway
0.55	GO:0043408	regulation of MAPK cascade
0.53	GO:0048468	cell development
0.53	GO:0042981	regulation of apoptotic process

0.78	GO:0008083	growth factor activity
0.59	GO:0005160	transforming growth factor beta receptor binding
0.56	GO:0005125	cytokine activity

0.66

GO:0005576

extracellular region

tr|Q4H2Q1|Q4H2Q1_CIOIN
Receptor protein serine/threonine kinase
Search

0.60	Receptor protein serine/threonine kinase

0.80	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
0.66	GO:0023014	signal transduction by protein phosphorylation
0.57	GO:0071363	cellular response to growth factor stimulus
0.57	GO:0071559	response to transforming growth factor beta
0.54	GO:0071495	cellular response to endogenous stimulus
0.52	GO:0071772	response to BMP
0.49	GO:0060836	lymphatic endothelial cell differentiation
0.49	GO:0035912	dorsal aorta morphogenesis
0.49	GO:0060562	epithelial tube morphogenesis
0.49	GO:0035313	wound healing, spreading of epidermal cells

0.83	GO:0004675	transmembrane receptor protein serine/threonine kinase activity
0.80	GO:0004702	signal transducer, downstream of receptor, with serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0050431	transforming growth factor beta binding
0.49	GO:0048185	activin binding
0.48	GO:0046332	SMAD binding
0.45	GO:0019901	protein kinase binding

0.47	GO:0043235	receptor complex
0.45	GO:0009986	cell surface
0.44	GO:0035230	cytoneme
0.43	GO:0005771	multivesicular body
0.42	GO:0005887	integral component of plasma membrane
0.41	GO:0005769	early endosome
0.39	GO:0097458	neuron part
0.38	GO:0044456	synapse part
0.37	GO:0005829	cytosol
0.35	GO:0044297	cell body

0.83

GO:0004675

tr|Q4H2Q4|Q4H2Q4_CIOIN
Ci-TCFL1 protein
Search

VPS72

0.86	Vacuolar protein sorting-associated protein 72

0.84	GO:0043486	histone exchange
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.50	GO:0035019	somatic stem cell population maintenance
0.40	GO:0016569	covalent chromatin modification
0.37	GO:0018393	internal peptidyl-lysine acetylation
0.36	GO:0010605	negative regulation of macromolecule metabolic process
0.35	GO:0006511	ubiquitin-dependent protein catabolic process
0.35	GO:0006351	transcription, DNA-templated

0.48	GO:0042393	histone binding
0.37	GO:0004402	histone acetyltransferase activity
0.36	GO:0031625	ubiquitin protein ligase binding
0.35	GO:0016651	oxidoreductase activity, acting on NAD(P)H
0.34	GO:0003677	DNA binding

0.61	GO:0005634	nucleus
0.44	GO:0031974	membrane-enclosed lumen
0.41	GO:0043234	protein complex
0.41	GO:0044446	intracellular organelle part
0.36	GO:0031248	protein acetyltransferase complex

0.37

GO:0004402

tr|Q4H2Q6|Q4H2Q6_CIOIN
Ci-Tardbp protein
Search

TARDBP

0.85	RNA-binding protein musashi

0.42	GO:0006366	transcription by RNA polymerase II
0.42	GO:0045944	positive regulation of transcription by RNA polymerase II
0.41	GO:0071765	nuclear inner membrane organization
0.40	GO:0043922	negative regulation by host of viral transcription
0.40	GO:0070935	3'-UTR-mediated mRNA stabilization
0.38	GO:0048675	axon extension
0.38	GO:0008380	RNA splicing
0.38	GO:0007519	skeletal muscle tissue development
0.38	GO:0007626	locomotory behavior
0.38	GO:0001933	negative regulation of protein phosphorylation

0.59	GO:0003723	RNA binding
0.46	GO:0003677	DNA binding
0.45	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding
0.37	GO:0042802	identical protein binding

0.37	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

tr|Q4H2Q8|Q4H2Q8_CIOIN
Ci-SWI/SNF protein
Search

SMARCA5

0.90	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

0.81	GO:0043044	ATP-dependent chromatin remodeling
0.74	GO:0016569	covalent chromatin modification
0.48	GO:0016584	nucleosome positioning
0.47	GO:0000183	chromatin silencing at rDNA
0.47	GO:1990823	response to leukemia inhibitory factor
0.45	GO:0006334	nucleosome assembly
0.45	GO:0071345	cellular response to cytokine stimulus
0.43	GO:0045893	positive regulation of transcription, DNA-templated
0.42	GO:0006352	DNA-templated transcription, initiation
0.42	GO:0048513	animal organ development

0.83	GO:0031491	nucleosome binding
0.67	GO:0004386	helicase activity
0.61	GO:0016887	ATPase activity
0.55	GO:0030554	adenyl nucleotide binding
0.55	GO:0003677	DNA binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0042393	histone binding
0.33	GO:0008081	phosphoric diester hydrolase activity

0.84	GO:0016589	NURF complex
0.48	GO:0031213	RSF complex
0.48	GO:0005677	chromatin silencing complex
0.47	GO:0001650	fibrillar center
0.47	GO:0043596	nuclear replication fork
0.45	GO:0000793	condensed chromosome
0.30	GO:0031224	intrinsic component of membrane

0.61

GO:0016887

tr|Q4H2R0|Q4H2R0_CIOIN
Ci-STAT-b protein
Search

0.70	Signal transducer and activator of transcription

0.85	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway
0.56	GO:0006351	transcription, DNA-templated
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0046543	development of secondary female sexual characteristics
0.53	GO:0008284	positive regulation of cell proliferation
0.52	GO:0045647	negative regulation of erythrocyte differentiation
0.52	GO:0001779	natural killer cell differentiation
0.52	GO:0045086	positive regulation of interleukin-2 biosynthetic process

0.63	GO:0004871	signal transducer activity
0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0003677	DNA binding
0.49	GO:0035259	glucocorticoid receptor binding
0.44	GO:0001067	regulatory region nucleic acid binding
0.42	GO:0046983	protein dimerization activity
0.36	GO:0003682	chromatin binding
0.35	GO:0004713	protein tyrosine kinase activity

0.61	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.41	GO:0070013	intracellular organelle lumen
0.39	GO:0044446	intracellular organelle part

0.35

EC:2.7.10

GO:0004713

sp|Q4H2R2|SSRP1_CIOIN
FACT complex subunit SSRP1
Search

SSRP1

0.75	FACT complex subunit SSRP1

0.65	GO:0006260	DNA replication
0.64	GO:0006281	DNA repair
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.36	GO:0051726	regulation of cell cycle
0.35	GO:1901796	regulation of signal transduction by p53 class mediator

0.55	GO:0003677	DNA binding
0.51	GO:0003682	chromatin binding
0.34	GO:0005515	protein binding
0.33	GO:0003723	RNA binding

0.67	GO:0005694	chromosome
0.61	GO:0005634	nucleus
0.38	GO:0031974	membrane-enclosed lumen
0.36	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

tr|Q4H2R3|Q4H2R3_CIOIN
Transcription factor protein
Search

0.48	Serum Response Factor

0.73	GO:0045944	positive regulation of transcription by RNA polymerase II
0.58	GO:0006351	transcription, DNA-templated
0.45	GO:0035209	pupal development
0.45	GO:0007430	terminal branching, open tracheal system
0.45	GO:0007475	apposition of dorsal and ventral imaginal disc-derived wing surfaces
0.45	GO:0007614	short-term memory
0.45	GO:0008586	imaginal disc-derived wing vein morphogenesis
0.44	GO:0002168	instar larval development
0.44	GO:0030431	sleep
0.41	GO:0030154	cell differentiation

0.78	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.77	GO:0000987	proximal promoter sequence-specific DNA binding
0.68	GO:0046983	protein dimerization activity
0.44	GO:0033613	activating transcription factor binding
0.43	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.36	GO:0070878	primary miRNA binding
0.36	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding
0.36	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.36	GO:0031490	chromatin DNA binding
0.35	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding

0.61	GO:0005634	nucleus
0.35	GO:0000785	chromatin
0.34	GO:0070013	intracellular organelle lumen
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|Q4H2R5|Q4H2R5_CIOIN
Transcription elongation factor SPT4
Search

SUPT4H1

0.68	Transcription elongation factor SPT4-A

0.81	GO:0032786	positive regulation of DNA-templated transcription, elongation
0.58	GO:0006414	translational elongation
0.55	GO:0006351	transcription, DNA-templated
0.54	GO:0032785	negative regulation of DNA-templated transcription, elongation
0.53	GO:0034243	regulation of transcription elongation from RNA polymerase II promoter
0.49	GO:0000122	negative regulation of transcription by RNA polymerase II
0.48	GO:0045944	positive regulation of transcription by RNA polymerase II
0.45	GO:0006325	chromatin organization
0.44	GO:0006397	mRNA processing
0.34	GO:0050434	positive regulation of viral transcription

0.63	GO:0008270	zinc ion binding
0.58	GO:0003746	translation elongation factor activity
0.49	GO:0000993	RNA polymerase II core binding
0.47	GO:0003727	single-stranded RNA binding
0.47	GO:0046982	protein heterodimerization activity
0.41	GO:0003700	DNA binding transcription factor activity
0.34	GO:0000182	rDNA binding

0.61	GO:0005634	nucleus
0.48	GO:0031974	membrane-enclosed lumen
0.44	GO:0043234	protein complex
0.43	GO:0044446	intracellular organelle part
0.33	GO:0015629	actin cytoskeleton
0.33	GO:0005694	chromosome
0.30	GO:0031224	intrinsic component of membrane

tr|Q4H2S1|Q4H2S1_CIOIN
Transcription factor protein
Search

0.47	HMG transcription factor SoxC

0.48	GO:0016331	morphogenesis of embryonic epithelium
0.48	GO:2000761	positive regulation of N-terminal peptidyl-lysine acetylation
0.47	GO:0002328	pro-B cell differentiation
0.47	GO:0003357	noradrenergic neuron differentiation
0.47	GO:0035910	ascending aorta morphogenesis
0.46	GO:0003289	atrial septum primum morphogenesis
0.46	GO:0014009	glial cell proliferation
0.46	GO:0046826	negative regulation of protein export from nucleus
0.46	GO:0042769	DNA damage response, detection of DNA damage
0.46	GO:0003211	cardiac ventricle formation

0.55	GO:0003677	DNA binding
0.46	GO:0003700	DNA binding transcription factor activity
0.45	GO:0001105	RNA polymerase II transcription coactivator activity
0.44	GO:0001067	regulatory region nucleic acid binding
0.42	GO:0046982	protein heterodimerization activity

0.61	GO:0005634	nucleus
0.42	GO:0005667	transcription factor complex
0.40	GO:0070013	intracellular organelle lumen
0.38	GO:0005739	mitochondrion
0.38	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

tr|Q4H2S2|Q4H2S2_CIOIN
Transcription factor protein
Search

0.52	Transcription factor Sox-1

0.55	GO:0007399	nervous system development
0.51	GO:1903506	regulation of nucleic acid-templated transcription
0.51	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.50	GO:0010468	regulation of gene expression
0.43	GO:0060573	cell fate specification involved in pattern specification
0.43	GO:0002089	lens morphogenesis in camera-type eye
0.42	GO:1990830	cellular response to leukemia inhibitory factor
0.42	GO:0009953	dorsal/ventral pattern formation
0.41	GO:0048518	positive regulation of biological process
0.41	GO:0060322	head development

0.55	GO:0003677	DNA binding
0.42	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.41	GO:0001067	regulatory region nucleic acid binding
0.33	GO:0070001	aspartic-type peptidase activity
0.33	GO:0004175	endopeptidase activity
0.33	GO:0005515	protein binding
0.33	GO:0008270	zinc ion binding

0.61	GO:0005634	nucleus
0.33	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

tr|Q4H2T4|Q4H2T4_CIOIN
Mothers against decapentaplegic homolog
Search

0.65	Mothers against decapentaplegic homolog

0.82	GO:0007179	transforming growth factor beta receptor signaling pathway
0.57	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.46	GO:0003251	positive regulation of cell proliferation involved in heart valve morphogenesis
0.46	GO:1905305	negative regulation of cardiac myofibril assembly
0.45	GO:0061040	female gonad morphogenesis
0.45	GO:0003220	left ventricular cardiac muscle tissue morphogenesis
0.45	GO:0072134	nephrogenic mesenchyme morphogenesis

0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0003677	DNA binding
0.45	GO:0030616	transforming growth factor beta receptor, common-partner cytoplasmic mediator activity
0.45	GO:0043199	sulfate binding
0.44	GO:0070411	I-SMAD binding
0.44	GO:0070412	R-SMAD binding
0.43	GO:0001085	RNA polymerase II transcription factor binding
0.43	GO:0005518	collagen binding
0.42	GO:0046982	protein heterodimerization activity
0.41	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding

0.74	GO:0005667	transcription factor complex
0.61	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.46	GO:0071141	SMAD protein complex
0.42	GO:0005813	centrosome
0.40	GO:0000785	chromatin
0.39	GO:0070013	intracellular organelle lumen
0.30	GO:0016020	membrane

tr|Q4H2T5|Q4H2T5_CIOIN
Mothers against decapentaplegic homolog
Search

SMAD3

0.65	Mothers against decapentaplegic homolog

0.82	GO:0007179	transforming growth factor beta receptor signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:0006355	regulation of transcription, DNA-templated
0.53	GO:0033689	negative regulation of osteoblast proliferation
0.53	GO:0048617	embryonic foregut morphogenesis
0.53	GO:0007183	SMAD protein complex assembly
0.53	GO:0048340	paraxial mesoderm morphogenesis
0.53	GO:0051481	negative regulation of cytosolic calcium ion concentration
0.53	GO:0002076	osteoblast development
0.53	GO:0038092	nodal signaling pathway

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0031962	mineralocorticoid receptor binding
0.54	GO:0003677	DNA binding
0.54	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
0.53	GO:0035259	glucocorticoid receptor binding
0.53	GO:0017151	DEAD/H-box RNA helicase binding
0.53	GO:0070410	co-SMAD binding
0.53	GO:0070878	primary miRNA binding
0.52	GO:0070412	R-SMAD binding
0.52	GO:0043425	bHLH transcription factor binding

0.74	GO:0005667	transcription factor complex
0.61	GO:0005634	nucleus
0.53	GO:0071141	SMAD protein complex
0.48	GO:0005737	cytoplasm
0.48	GO:0043235	receptor complex
0.46	GO:0000785	chromatin
0.44	GO:0070013	intracellular organelle lumen
0.44	GO:0012505	endomembrane system
0.42	GO:0019866	organelle inner membrane
0.40	GO:0005886	plasma membrane

tr|Q4H2T6|Q4H2T6_CIOIN
Mothers against decapentaplegic homolog
Search

SMAD3

0.65	Mothers against decapentaplegic homolog

0.82	GO:0007179	transforming growth factor beta receptor signaling pathway
0.57	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0007183	SMAD protein complex assembly
0.53	GO:0038092	nodal signaling pathway
0.53	GO:0048617	embryonic foregut morphogenesis
0.52	GO:0048340	paraxial mesoderm morphogenesis
0.52	GO:0060039	pericardium development

0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0003677	DNA binding
0.54	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
0.53	GO:0070410	co-SMAD binding
0.53	GO:0070878	primary miRNA binding
0.52	GO:0070412	R-SMAD binding
0.52	GO:0031962	mineralocorticoid receptor binding
0.51	GO:0005160	transforming growth factor beta receptor binding
0.51	GO:0033613	activating transcription factor binding
0.50	GO:0035259	glucocorticoid receptor binding

0.74	GO:0005667	transcription factor complex
0.61	GO:0005634	nucleus
0.53	GO:0071141	SMAD protein complex
0.48	GO:0005737	cytoplasm
0.46	GO:0043235	receptor complex
0.46	GO:0000785	chromatin
0.44	GO:0070013	intracellular organelle lumen
0.42	GO:0012505	endomembrane system
0.41	GO:0019866	organelle inner membrane
0.39	GO:0005886	plasma membrane

tr|Q4H2U4|Q4H2U4_CIOIN
Secreted frizzled-related protein
Search

0.83	secreted frizzled-related protein precursor

0.66	GO:0016055	Wnt signaling pathway
0.65	GO:0007275	multicellular organism development
0.57	GO:0030510	regulation of BMP signaling pathway
0.56	GO:0030111	regulation of Wnt signaling pathway
0.54	GO:0071481	cellular response to X-ray
0.54	GO:0043508	negative regulation of JUN kinase activity
0.54	GO:0090178	regulation of establishment of planar polarity involved in neural tube closure
0.53	GO:0060028	convergent extension involved in axis elongation
0.53	GO:0010719	negative regulation of epithelial to mesenchymal transition
0.53	GO:0045578	negative regulation of B cell differentiation

0.56	GO:0017147	Wnt-protein binding
0.50	GO:0005109	frizzled binding
0.49	GO:0042813	Wnt-activated receptor activity
0.48	GO:0008201	heparin binding
0.46	GO:0004197	cysteine-type endopeptidase activity
0.45	GO:0042802	identical protein binding
0.44	GO:0004930	G-protein coupled receptor activity
0.41	GO:0061133	endopeptidase activator activity
0.39	GO:0048018	receptor ligand activity
0.38	GO:0008144	drug binding

0.61	GO:0005576	extracellular region
0.46	GO:0009986	cell surface
0.43	GO:0005829	cytosol
0.33	GO:0005886	plasma membrane
0.33	GO:0031982	vesicle
0.30	GO:0016021	integral component of membrane

0.46

EC:3.4.22

GO:0004197

tr|Q4H2U5|Q4H2U5_CIOIN
Secreted frizzled-related protein
Search

0.69	secreted frizzled-related protein precursor

0.75	GO:0016055	Wnt signaling pathway
0.70	GO:0007275	multicellular organism development
0.64	GO:0030510	regulation of BMP signaling pathway
0.63	GO:0030111	regulation of Wnt signaling pathway
0.56	GO:0035412	regulation of catenin import into nucleus
0.54	GO:2000026	regulation of multicellular organismal development
0.54	GO:0043508	negative regulation of JUN kinase activity
0.54	GO:0071481	cellular response to X-ray
0.54	GO:0060028	convergent extension involved in axis elongation
0.53	GO:0008285	negative regulation of cell proliferation

0.58	GO:0017147	Wnt-protein binding
0.55	GO:0042813	Wnt-activated receptor activity
0.51	GO:0061133	endopeptidase activator activity
0.47	GO:0005102	receptor binding
0.46	GO:0030545	receptor regulator activity
0.45	GO:0004930	G-protein coupled receptor activity
0.39	GO:0008201	heparin binding
0.38	GO:0004197	cysteine-type endopeptidase activity
0.38	GO:0042802	identical protein binding
0.35	GO:0001968	fibronectin binding

0.63	GO:0005576	extracellular region
0.38	GO:0009986	cell surface
0.37	GO:0005829	cytosol
0.37	GO:0005768	endosome
0.35	GO:0005887	integral component of plasma membrane

0.38

EC:3.4.22

GO:0004197

tr|Q4H2U9|Q4H2U9_CIOIN
Nuclear receptor
Search

0.71	Retinoid X receptor alpha

0.79	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0048384	retinoic acid receptor signaling pathway
0.53	GO:0051289	protein homotetramerization
0.48	GO:0051254	positive regulation of RNA metabolic process
0.48	GO:0010557	positive regulation of macromolecule biosynthetic process
0.48	GO:0031328	positive regulation of cellular biosynthetic process

0.80	GO:0003707	steroid hormone receptor activity
0.64	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.50	GO:0001012	RNA polymerase II regulatory region DNA binding
0.48	GO:0003690	double-stranded DNA binding
0.42	GO:0050692	DBD domain binding
0.42	GO:0050693	LBD domain binding
0.42	GO:0042809	vitamin D receptor binding
0.42	GO:0001972	retinoic acid binding

0.61	GO:0005634	nucleus
0.39	GO:0043235	receptor complex
0.39	GO:0005667	transcription factor complex
0.38	GO:0000785	chromatin
0.37	GO:0043233	organelle lumen

tr|Q4H2V9|Q4H2V9_CIOIN
RelA
Search

0.72	V-rel avian reticuloendotheliosis viral oncogene homolog A

0.69	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.59	GO:0007249	I-kappaB kinase/NF-kappaB signaling
0.57	GO:0010628	positive regulation of gene expression
0.56	GO:0006357	regulation of transcription by RNA polymerase II
0.56	GO:1903508	positive regulation of nucleic acid-templated transcription
0.55	GO:0038061	NIK/NF-kappaB signaling
0.53	GO:0034097	response to cytokine
0.52	GO:0006954	inflammatory response
0.52	GO:0071224	cellular response to peptidoglycan
0.52	GO:0001817	regulation of cytokine production

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.54	GO:0001067	regulatory region nucleic acid binding
0.52	GO:0071532	ankyrin repeat binding
0.52	GO:0003682	chromatin binding
0.51	GO:0019901	protein kinase binding
0.50	GO:0051059	NF-kappaB binding
0.49	GO:0070491	repressing transcription factor binding
0.49	GO:0042802	identical protein binding
0.49	GO:0047485	protein N-terminus binding

0.73	GO:0071159	NF-kappaB complex
0.61	GO:0005634	nucleus
0.53	GO:0033256	I-kappaB/NF-kappaB complex
0.50	GO:0005829	cytosol
0.46	GO:0070013	intracellular organelle lumen
0.46	GO:0005667	transcription factor complex
0.45	GO:0000785	chromatin
0.43	GO:0005813	centrosome
0.30	GO:0016020	membrane

tr|Q4H2W4|Q4H2W4_CIOIN
Ci-PUR-alpha/beta/gamma protein
Search

PURA

0.93	transcriptional activator protein Pur-alpha

0.72	GO:0030154	cell differentiation
0.71	GO:0045892	negative regulation of transcription, DNA-templated
0.66	GO:0042127	regulation of cell proliferation
0.62	GO:0008283	cell proliferation
0.49	GO:0006268	DNA unwinding involved in DNA replication
0.47	GO:0017148	negative regulation of translation
0.47	GO:0007399	nervous system development
0.45	GO:0048522	positive regulation of cellular process
0.37	GO:0006357	regulation of transcription by RNA polymerase II
0.36	GO:0006351	transcription, DNA-templated

0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0032422	purine-rich negative regulatory element binding
0.54	GO:0003691	double-stranded telomeric DNA binding
0.53	GO:0003723	RNA binding
0.52	GO:0000900	translation repressor activity, nucleic acid binding
0.52	GO:0046332	SMAD binding
0.49	GO:0003697	single-stranded DNA binding
0.48	GO:0008134	transcription factor binding
0.37	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.33	GO:0016675	oxidoreductase activity, acting on a heme group of donors

0.55	GO:0005662	DNA replication factor A complex
0.49	GO:0043025	neuronal cell body
0.49	GO:0030425	dendrite
0.38	GO:0005737	cytoplasm
0.35	GO:0000784	nuclear chromosome, telomeric region
0.33	GO:0031967	organelle envelope
0.30	GO:0016020	membrane

0.33

EC:1.9

GO:0016675

tr|Q4H2W8|Q4H2W8_CIOIN
Transcription factor protein
Search

PROX-B

0.53	transcription factor protein isoform X1

0.56	GO:0000122	negative regulation of transcription by RNA polymerase II
0.55	GO:0030182	neuron differentiation
0.54	GO:0045944	positive regulation of transcription by RNA polymerase II

0.59	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.55	GO:0003677	DNA binding

0.47

GO:0005634

nucleus

tr|Q4H2W9|Q4H2W9_CIOIN
Transcription factor protein (Fragment)
Search

0.62	Transcription factor protein (Fragment)

0.68	GO:0000122	negative regulation of transcription by RNA polymerase II
0.68	GO:0030182	neuron differentiation
0.66	GO:0045944	positive regulation of transcription by RNA polymerase II

0.73	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.55	GO:0003677	DNA binding

0.55

GO:0005634

nucleus

tr|Q4H2X3|Q4H2X3_CIOIN
Transcription factor protein (Fragment)
Search

0.58	Transcription factor protein (Fragment)

0.65	GO:0001755	neural crest cell migration
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.54	GO:0048704	embryonic skeletal system morphogenesis
0.49	GO:0010718	positive regulation of epithelial to mesenchymal transition
0.49	GO:0030326	embryonic limb morphogenesis
0.48	GO:0060021	palate development
0.48	GO:0001843	neural tube closure
0.47	GO:0009952	anterior/posterior pattern specification

0.63	GO:0043565	sequence-specific DNA binding
0.50	GO:0003700	DNA binding transcription factor activity
0.46	GO:0001012	RNA polymerase II regulatory region DNA binding
0.44	GO:0046982	protein heterodimerization activity
0.44	GO:0003690	double-stranded DNA binding
0.36	GO:0042803	protein homodimerization activity
0.33	GO:0003714	transcription corepressor activity
0.33	GO:0004000	adenosine deaminase activity

0.61	GO:0005634	nucleus
0.45	GO:0005667	transcription factor complex
0.44	GO:0005794	Golgi apparatus
0.43	GO:0043233	organelle lumen
0.39	GO:0044446	intracellular organelle part

0.33

EC:3.5.4.4

GO:0004000

tr|Q4H2X6|Q4H2X6_CIOIN
Nuclear receptor
Search

0.53	nuclear receptor

0.79	GO:0030522	intracellular receptor signaling pathway
0.75	GO:0043401	steroid hormone mediated signaling pathway
0.60	GO:0048511	rhythmic process
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.48	GO:0010887	negative regulation of cholesterol storage
0.48	GO:0010871	negative regulation of receptor biosynthetic process
0.48	GO:0010891	negative regulation of sequestering of triglyceride

0.82	GO:0004879	nuclear receptor activity
0.77	GO:0003707	steroid hormone receptor activity
0.63	GO:0043565	sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.44	GO:0050692	DBD domain binding
0.44	GO:0050693	LBD domain binding
0.44	GO:0046965	retinoid X receptor binding
0.44	GO:0044212	transcription regulatory region DNA binding
0.43	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
0.43	GO:0051393	alpha-actinin binding

0.61	GO:0005634	nucleus
0.41	GO:0005737	cytoplasm
0.40	GO:0005667	transcription factor complex
0.38	GO:0044446	intracellular organelle part
0.37	GO:0070013	intracellular organelle lumen
0.30	GO:0016020	membrane

tr|Q4H2Y1|Q4H2Y1_CIOIN
Transcription factor protein
Search

0.49	paired superclass homeobox transcription factor isoform X1

0.69	GO:0007275	multicellular organism development
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.51	GO:2000288	positive regulation of myoblast proliferation
0.51	GO:0003228	atrial cardiac muscle tissue development
0.50	GO:0060322	head development
0.50	GO:0048857	neural nucleus development
0.50	GO:0051145	smooth muscle cell differentiation
0.49	GO:0007520	myoblast fusion

0.65	GO:0043565	sequence-specific DNA binding
0.58	GO:0003700	DNA binding transcription factor activity
0.51	GO:0001105	RNA polymerase II transcription coactivator activity
0.51	GO:0001102	RNA polymerase II activating transcription factor binding
0.48	GO:0031490	chromatin DNA binding
0.47	GO:0044212	transcription regulatory region DNA binding
0.45	GO:0003690	double-stranded DNA binding
0.37	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.37	GO:0051219	phosphoprotein binding
0.36	GO:0042803	protein homodimerization activity

0.61	GO:0005634	nucleus
0.47	GO:0005667	transcription factor complex
0.37	GO:0005737	cytoplasm
0.33	GO:0070013	intracellular organelle lumen
0.33	GO:0005576	extracellular region
0.32	GO:0044446	intracellular organelle part

0.33

EC:3.1.1.3

GO:0004806

tr|Q4H2Z5|Q4H2Z5_CIOIN
Transcription factor protein
Search

0.51	homeobox transcription factor Pax1/9

0.70	GO:0007275	multicellular organism development
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.49	GO:0009653	anatomical structure morphogenesis
0.48	GO:0036037	CD8-positive, alpha-beta T cell activation
0.47	GO:0035710	CD4-positive, alpha-beta T cell activation
0.46	GO:0030154	cell differentiation
0.45	GO:0008283	cell proliferation

0.58	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.44	GO:0001067	regulatory region nucleic acid binding
0.34	GO:0005249	voltage-gated potassium channel activity

0.61	GO:0005634	nucleus
0.33	GO:0005667	transcription factor complex
0.33	GO:0005887	integral component of plasma membrane

tr|Q4H2Z7|Q4H2Z7_CIOIN
Transcription factor protein
Search

0.45	transcription factor protein

0.63	GO:0006357	regulation of transcription by RNA polymerase II
0.39	GO:0007281	germ cell development

0.68	GO:0046983	protein dimerization activity
0.50	GO:0003677	DNA binding
0.41	GO:0001067	regulatory region nucleic acid binding
0.38	GO:0003729	mRNA binding
0.37	GO:0003700	DNA binding transcription factor activity

0.41

GO:0090575

RNA polymerase II transcription factor complex

tr|Q4H301|Q4H301_CIOIN
Transcription factor protein
Search

0.55	transcription factor protein isoform X5

0.80	GO:0051262	protein tetramerization
0.78	GO:0006915	apoptotic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.51	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
0.50	GO:0010165	response to X-ray
0.50	GO:0031571	mitotic G1 DNA damage checkpoint
0.49	GO:0010332	response to gamma radiation
0.49	GO:0034644	cellular response to UV

0.76	GO:0044212	transcription regulatory region DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.49	GO:0002039	p53 binding
0.46	GO:0003682	chromatin binding
0.45	GO:0003684	damaged DNA binding
0.45	GO:0003690	double-stranded DNA binding
0.42	GO:0043565	sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.46	GO:0005667	transcription factor complex
0.45	GO:0000785	chromatin
0.43	GO:0005829	cytosol

tr|Q4H303|Q4H303_CIOIN
Transcription factor protein
Search

0.54	Homeobox protein Otx

0.64	GO:0007623	circadian rhythm
0.62	GO:0007275	multicellular organism development
0.61	GO:0007601	visual perception
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.50	GO:0006366	transcription by RNA polymerase II
0.49	GO:1902680	positive regulation of RNA biosynthetic process
0.44	GO:0060322	head development
0.43	GO:0009653	anatomical structure morphogenesis

0.65	GO:0043565	sequence-specific DNA binding
0.55	GO:0003700	DNA binding transcription factor activity
0.51	GO:0001012	RNA polymerase II regulatory region DNA binding
0.50	GO:0043522	leucine zipper domain binding
0.48	GO:0003690	double-stranded DNA binding
0.40	GO:0035257	nuclear hormone receptor binding
0.36	GO:0003682	chromatin binding
0.34	GO:0003743	translation initiation factor activity

0.61	GO:0005634	nucleus
0.36	GO:0005667	transcription factor complex

tr|Q4H306|Q4H306_CIOIN
Protein Wnt (Fragment)
Search

0.77	GO:0016055	Wnt signaling pathway
0.70	GO:0007275	multicellular organism development
0.62	GO:0070172	positive regulation of tooth mineralization
0.61	GO:0060684	epithelial-mesenchymal cell signaling
0.57	GO:0061138	morphogenesis of a branching epithelium
0.53	GO:0048646	anatomical structure formation involved in morphogenesis
0.52	GO:0045893	positive regulation of transcription, DNA-templated
0.51	GO:0045165	cell fate commitment
0.43	GO:0070654	sensory epithelium regeneration
0.37	GO:0071300	cellular response to retinoic acid

0.72	GO:0005102	receptor binding
0.33	GO:0020037	heme binding
0.33	GO:0009055	electron transfer activity

0.75	GO:0005578	proteinaceous extracellular matrix
0.53	GO:0009986	cell surface
0.48	GO:0005615	extracellular space
0.39	GO:0005788	endoplasmic reticulum lumen
0.37	GO:0005796	Golgi lumen
0.36	GO:0030666	endocytic vesicle membrane
0.36	GO:1903561	extracellular vesicle
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|Q4H307|Q4H307_CIOIN
Protein Wnt (Fragment)
Search

tr|Q4H308|Q4H308_CIOIN
Protein Wnt
Search

0.77	GO:0016055	Wnt signaling pathway
0.70	GO:0007275	multicellular organism development
0.47	GO:0045165	cell fate commitment
0.45	GO:0008283	cell proliferation
0.45	GO:0031945	positive regulation of glucocorticoid metabolic process
0.45	GO:0061369	negative regulation of testicular blood vessel morphogenesis
0.45	GO:2000019	negative regulation of male gonad development
0.44	GO:0040019	positive regulation of embryonic development
0.44	GO:2000225	negative regulation of testosterone biosynthetic process
0.44	GO:0032346	positive regulation of aldosterone metabolic process

0.73	GO:0005102	receptor binding
0.41	GO:0003714	transcription corepressor activity
0.37	GO:0030545	receptor regulator activity
0.34	GO:1990782	protein tyrosine kinase binding
0.34	GO:0039706	co-receptor binding

0.75	GO:0005578	proteinaceous extracellular matrix
0.45	GO:0005615	extracellular space
0.40	GO:0009986	cell surface
0.35	GO:0005737	cytoplasm
0.34	GO:0012505	endomembrane system
0.33	GO:0005886	plasma membrane
0.33	GO:0070013	intracellular organelle lumen
0.33	GO:0043231	intracellular membrane-bounded organelle
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

tr|Q4H329|Q4H329_CIOIN
Transcription factor protein
Search

NFYB

0.80	Nuclear transcription factor Y subunit beta

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.52	GO:1990830	cellular response to leukemia inhibitory factor
0.47	GO:1902680	positive regulation of RNA biosynthetic process
0.36	GO:0006351	transcription, DNA-templated
0.35	GO:0045540	regulation of cholesterol biosynthetic process

0.72	GO:0046982	protein heterodimerization activity
0.63	GO:0043565	sequence-specific DNA binding
0.52	GO:0070491	repressing transcription factor binding
0.51	GO:0035326	enhancer binding
0.48	GO:0001012	RNA polymerase II regulatory region DNA binding
0.46	GO:0003690	double-stranded DNA binding
0.42	GO:0003700	DNA binding transcription factor activity
0.37	GO:0032403	protein complex binding

0.60	GO:0005634	nucleus
0.48	GO:0005667	transcription factor complex
0.46	GO:0032993	protein-DNA complex
0.41	GO:0044446	intracellular organelle part
0.34	GO:0043233	organelle lumen

tr|Q4H336|Q4H336_CIOIN
Noggin
Search

0.84	noggin protein precursor

0.85	GO:0030514	negative regulation of BMP signaling pathway
0.79	GO:0045596	negative regulation of cell differentiation
0.70	GO:0051216	cartilage development
0.62	GO:0030154	cell differentiation
0.58	GO:0060825	fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation
0.58	GO:2000313	regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation
0.57	GO:0060302	negative regulation of cytokine activity
0.56	GO:0060513	prostatic bud formation
0.56	GO:0061312	BMP signaling pathway involved in heart development
0.56	GO:0060676	ureteric bud formation

0.53	GO:0019955	cytokine binding
0.49	GO:0042803	protein homodimerization activity
0.34	GO:0032403	protein complex binding

0.58	GO:0005576	extracellular region
0.34	GO:0030424	axon
0.33	GO:0043234	protein complex
0.30	GO:0016020	membrane

tr|Q4H342|Q4H342_CIOIN
Transcription factor protein
Search

0.47	transcription factor protein

0.58	GO:0048513	animal organ development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:1903779	regulation of cardiac conduction
0.56	GO:0072359	circulatory system development
0.55	GO:0060048	cardiac muscle contraction
0.53	GO:0035295	tube development
0.53	GO:0055123	digestive system development
0.52	GO:0009888	tissue development

0.64	GO:0043565	sequence-specific DNA binding
0.46	GO:0003700	DNA binding transcription factor activity
0.34	GO:0005179	hormone activity

0.61	GO:0005634	nucleus
0.33	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

tr|Q4H352|Q4H352_CIOIN
Ci-NF45 protein
Search

ILF2

0.84	Interleukin enhancer binding factor 2

0.74	GO:0006955	immune response
0.44	GO:0045893	positive regulation of transcription, DNA-templated
0.39	GO:0006351	transcription, DNA-templated
0.34	GO:0002446	neutrophil mediated immunity
0.34	GO:0043299	leukocyte degranulation
0.34	GO:0042119	neutrophil activation

0.59	GO:0003723	RNA binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0016740	transferase activity
0.38	GO:0003677	DNA binding
0.34	GO:0005515	protein binding

0.44	GO:0005730	nucleolus
0.41	GO:0005576	extracellular region
0.40	GO:0030529	intracellular ribonucleoprotein complex
0.35	GO:1904724	tertiary granule lumen
0.35	GO:0035580	specific granule lumen
0.35	GO:1904813	ficolin-1-rich granule lumen
0.30	GO:0016020	membrane

0.51

EC:2

GO:0016740

tr|Q4H355|Q4H355_CIOIN
Ci-Neuralized-b protein
Search

0.92	Ci-Neuralized-b protein

tr|Q4H356|Q4H356_CIOIN
Ci-Neuralized-a protein
Search

NEURALIZED-A

0.97	neuralized-a protein isoform X2

0.68	GO:0070647	protein modification by small protein conjugation or removal
0.57	GO:0006996	organelle organization
0.55	GO:0008612	peptidyl-lysine modification to peptidyl-hypusine
0.55	GO:0090141	positive regulation of mitochondrial fission
0.45	GO:0006508	proteolysis

0.64	GO:0004842	ubiquitin-protein transferase activity
0.53	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.47	GO:0016874	ligase activity
0.42	GO:0046872	metal ion binding
0.37	GO:0003676	nucleic acid binding
0.36	GO:0004386	helicase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.38	GO:0031307	integral component of mitochondrial outer membrane
0.37	GO:0005777	peroxisome

0.53	EC:3.4.19.12	GO:0036459
0.64	KEGG:R03876	GO:0004842

tr|Q4H357|Q4H357_CIOIN
Transcription factor protein (Fragment)
Search

0.58	Transcription factor protein (Fragment)

0.72	GO:0030154	cell differentiation
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.50	GO:0045603	positive regulation of endothelial cell differentiation
0.49	GO:0001937	negative regulation of endothelial cell proliferation
0.49	GO:0051450	myoblast proliferation
0.48	GO:0060395	SMAD protein signal transduction
0.48	GO:0010595	positive regulation of endothelial cell migration
0.48	GO:0035239	tube morphogenesis

0.68	GO:0046983	protein dimerization activity
0.61	GO:0003700	DNA binding transcription factor activity
0.49	GO:0070888	E-box binding
0.46	GO:0033613	activating transcription factor binding
0.34	GO:0005179	hormone activity
0.33	GO:0005262	calcium channel activity

0.43	GO:0005654	nucleoplasm
0.36	GO:0005737	cytoplasm
0.33	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

tr|Q4H358|Q4H358_CIOIN
Mitogen-activated protein kinase
Search

NLK

0.57	Mitogen-activated protein kinase

0.79	GO:0000165	MAPK cascade
0.54	GO:0018107	peptidyl-threonine phosphorylation
0.54	GO:0030111	regulation of Wnt signaling pathway
0.53	GO:0042501	serine phosphorylation of STAT protein
0.51	GO:0007179	transforming growth factor beta receptor signaling pathway
0.50	GO:0050821	protein stabilization
0.50	GO:0046777	protein autophosphorylation
0.47	GO:0009968	negative regulation of signal transduction
0.44	GO:0030901	midbrain development
0.42	GO:0009967	positive regulation of signal transduction

0.81	GO:0004707	MAP kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0042169	SH2 domain binding
0.50	GO:0031625	ubiquitin protein ligase binding
0.47	GO:0008134	transcription factor binding
0.43	GO:0000287	magnesium ion binding
0.34	GO:0047485	protein N-terminus binding
0.34	GO:0008013	beta-catenin binding

0.45	GO:0005622	intracellular
0.41	GO:0043227	membrane-bounded organelle
0.34	GO:1902554	serine/threonine protein kinase complex
0.32	GO:0071944	cell periphery

0.81	EC:2.7.11.24	GO:0004707
0.81	KEGG:R00162	GO:0004707

tr|Q4H363|Q4H363_CIOIN
Transcription factor protein
Search

0.47	Homeobox protein MOX-2

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.48	GO:0042663	regulation of endodermal cell fate specification
0.48	GO:0042661	regulation of mesodermal cell fate specification
0.47	GO:0009953	dorsal/ventral pattern formation
0.41	GO:0006366	transcription by RNA polymerase II
0.40	GO:1902680	positive regulation of RNA biosynthetic process
0.40	GO:0060061	Spemann organizer formation
0.39	GO:0036342	post-anal tail morphogenesis

0.61	GO:0043565	sequence-specific DNA binding
0.42	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.41	GO:0042803	protein homodimerization activity
0.40	GO:0046982	protein heterodimerization activity
0.36	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.34	GO:0016772	transferase activity, transferring phosphorus-containing groups
0.33	GO:0140097	catalytic activity, acting on DNA

0.61

GO:0005634

nucleus

0.34

EC:2.7

GO:0016772

tr|Q4H367|Q4H367_CIOIN
Transcription factor protein
Search

MLX

0.50	Transcription factor protein

0.59

GO:0006357

regulation of transcription by RNA polymerase II

0.68	GO:0046983	protein dimerization activity
0.52	GO:0003700	DNA binding transcription factor activity

0.52

GO:0005634

nucleus

tr|Q4H372|Q4H372_CIOIN
Ci-MTA protein
Search

MTA2

0.78	Metastasis associated 1

0.63	GO:0016575	histone deacetylation
0.62	GO:0000122	negative regulation of transcription by RNA polymerase II
0.60	GO:0045944	positive regulation of transcription by RNA polymerase II
0.59	GO:0006306	DNA methylation
0.51	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle
0.48	GO:0008284	positive regulation of cell proliferation
0.43	GO:0010762	regulation of fibroblast migration
0.43	GO:0060215	primitive hemopoiesis
0.39	GO:0031101	fin regeneration
0.38	GO:1902499	positive regulation of protein autoubiquitination

0.77	GO:0003682	chromatin binding
0.69	GO:0001103	RNA polymerase II repressing transcription factor binding
0.65	GO:0043565	sequence-specific DNA binding
0.64	GO:0004407	histone deacetylase activity
0.63	GO:0008270	zinc ion binding
0.62	GO:0044212	transcription regulatory region DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.60	GO:0000989	transcription factor activity, transcription factor binding
0.58	GO:0003690	double-stranded DNA binding
0.46	GO:0044877	macromolecular complex binding

0.76	GO:0090545	CHD-type complex
0.74	GO:0090568	nuclear transcriptional repressor complex
0.72	GO:0000118	histone deacetylase complex
0.60	GO:0005667	transcription factor complex
0.37	GO:0005737	cytoplasm
0.36	GO:0005635	nuclear envelope
0.36	GO:0005874	microtubule
0.30	GO:0016020	membrane

0.64

EC:3.5.1.98

GO:0004407

tr|Q4H373|Q4H373_CIOIN
Transcription factor protein
Search

0.52	Transcription factor protein

0.71	GO:0001707	mesoderm formation
0.70	GO:0001756	somitogenesis
0.69	GO:0009880	embryonic pattern specification
0.62	GO:0006366	transcription by RNA polymerase II
0.61	GO:0045944	positive regulation of transcription by RNA polymerase II
0.45	GO:0097101	blood vessel endothelial cell fate specification
0.44	GO:0003128	heart field specification
0.43	GO:0007379	segment specification
0.43	GO:0001702	gastrulation with mouth forming second
0.43	GO:0032526	response to retinoic acid

0.68	GO:0046983	protein dimerization activity
0.66	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.65	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding

0.52

GO:0005634

nucleus

tr|Q4H376|Q4H376_CIOIN
Transcription factor protein (Fragment)
Search

MAX

0.88	Transcription factor Max

0.44	GO:2001141	regulation of RNA biosynthetic process
0.44	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.44	GO:0010468	regulation of gene expression
0.39	GO:0051253	negative regulation of RNA metabolic process
0.39	GO:0010558	negative regulation of macromolecule biosynthetic process
0.39	GO:0031327	negative regulation of cellular biosynthetic process
0.36	GO:0048678	response to axon injury
0.36	GO:0051402	neuron apoptotic process
0.36	GO:0032868	response to insulin
0.36	GO:0060041	retina development in camera-type eye

0.68	GO:0046983	protein dimerization activity
0.47	GO:0003700	DNA binding transcription factor activity
0.43	GO:0070888	E-box binding
0.40	GO:0042802	identical protein binding
0.35	GO:0032403	protein complex binding
0.34	GO:0003713	transcription coactivator activity

0.82	GO:0071339	MLL1 complex
0.77	GO:0090575	RNA polymerase II transcription factor complex
0.40	GO:0000790	nuclear chromatin
0.39	GO:0032993	protein-DNA complex
0.36	GO:0016605	PML body
0.35	GO:0030425	dendrite
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|Q4H383|Q4H383_CIOIN
Mitogen-activated protein kinase kinase
Search

MAP2K1

0.77	Dual specificity mitogen-activated protein kinase kinase

0.63	GO:0006468	protein phosphorylation
0.47	GO:0070372	regulation of ERK1 and ERK2 cascade
0.46	GO:0032147	activation of protein kinase activity
0.45	GO:0007346	regulation of mitotic cell cycle
0.45	GO:0071481	cellular response to X-ray
0.45	GO:0042386	hemocyte differentiation
0.45	GO:0007362	terminal region determination
0.44	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA
0.44	GO:0007298	border follicle cell migration
0.44	GO:0031572	G2 DNA damage checkpoint

0.69	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0004708	MAP kinase kinase activity
0.44	GO:0097110	scaffold protein binding
0.43	GO:0043539	protein serine/threonine kinase activator activity
0.41	GO:0030165	PDZ domain binding
0.38	GO:0004713	protein tyrosine kinase activity

0.42	GO:0012505	endomembrane system
0.41	GO:0000793	condensed chromosome
0.40	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0005911	cell-cell junction
0.39	GO:0015630	microtubule cytoskeleton
0.39	GO:0009898	cytoplasmic side of plasma membrane
0.39	GO:0044446	intracellular organelle part
0.39	GO:0043231	intracellular membrane-bounded organelle
0.39	GO:0099512	supramolecular fiber
0.37	GO:0031975	envelope

0.69

GO:0004674

tr|Q4H389|Q4H389_CIOIN
Transcription factor protein
Search

0.45	Transcription factor protein

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.45	GO:1905962	glutamatergic neuron differentiation
0.45	GO:0030902	hindbrain development
0.44	GO:0035775	pronephric glomerulus morphogenesis
0.44	GO:0061386	closure of optic fissure
0.43	GO:0030917	midbrain-hindbrain boundary development
0.43	GO:0021591	ventricular system development
0.42	GO:0060041	retina development in camera-type eye

0.64	GO:0043565	sequence-specific DNA binding
0.53	GO:0046872	metal ion binding
0.38	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.38	GO:0001012	RNA polymerase II regulatory region DNA binding
0.37	GO:0003690	double-stranded DNA binding
0.34	GO:0030246	carbohydrate binding
0.33	GO:0016887	ATPase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.33

GO:0016887

tr|Q4H394|Q4H394_CIOIN
Transcription factor protein
Search

0.45	transcription factor protein

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:0010468	regulation of gene expression
0.47	GO:0021572	rhombomere 6 development
0.47	GO:0021571	rhombomere 5 development
0.47	GO:0048839	inner ear development
0.46	GO:1902680	positive regulation of RNA biosynthetic process
0.46	GO:0021598	abducens nerve morphogenesis
0.46	GO:0045647	negative regulation of erythrocyte differentiation

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.45	GO:0001067	regulatory region nucleic acid binding
0.41	GO:0008134	transcription factor binding
0.36	GO:0042803	protein homodimerization activity
0.36	GO:0046982	protein heterodimerization activity
0.34	GO:0043522	leucine zipper domain binding
0.33	GO:0003713	transcription coactivator activity
0.33	GO:0004045	aminoacyl-tRNA hydrolase activity
0.32	GO:0003924	GTPase activity

0.61	GO:0005634	nucleus
0.41	GO:0005667	transcription factor complex
0.34	GO:0005737	cytoplasm
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part
0.32	GO:0005694	chromosome
0.32	GO:0042025	host cell nucleus
0.30	GO:0016020	membrane

0.33

EC:3.1.1.29

GO:0004045

tr|Q4H396|Q4H396_CIOIN
Transcription factor protein
Search

CERS6

0.80	Ceramide synthase 6

0.51	GO:0046513	ceramide biosynthetic process
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.54	GO:0003677	DNA binding
0.52	GO:0050291	sphingosine N-acyltransferase activity

0.59	GO:0005634	nucleus
0.45	GO:0005783	endoplasmic reticulum
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0031984	organelle subcompartment
0.34	GO:0031967	organelle envelope
0.34	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

0.52

EC:2.3.1.24

GO:0050291

tr|Q4H398|Q4H398_CIOIN
Transcription factor protein
Search

0.71	Ceramide synthase 4

0.54	GO:0046513	ceramide biosynthetic process
0.37	GO:1903506	regulation of nucleic acid-templated transcription
0.37	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.37	GO:0010468	regulation of gene expression
0.31	GO:0005975	carbohydrate metabolic process

0.56	GO:0050291	sphingosine N-acyltransferase activity
0.53	GO:0003677	DNA binding
0.32	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.57	GO:0005634	nucleus
0.48	GO:0005783	endoplasmic reticulum
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0031984	organelle subcompartment
0.33	GO:0031967	organelle envelope
0.33	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

0.56

EC:2.3.1.24

GO:0050291

tr|Q4H3A1|Q4H3A1_CIOIN
Transcription factor protein
Search

JUND

0.67	Transcription factor jun-D

0.61	GO:0006357	regulation of transcription by RNA polymerase II
0.48	GO:0051591	response to cAMP
0.48	GO:0045597	positive regulation of cell differentiation
0.47	GO:0009612	response to mechanical stimulus
0.47	GO:0045893	positive regulation of transcription, DNA-templated
0.47	GO:0032496	response to lipopolysaccharide
0.46	GO:0034097	response to cytokine
0.46	GO:0010038	response to metal ion
0.45	GO:0051726	regulation of cell cycle
0.45	GO:0042127	regulation of cell proliferation

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.47	GO:0001067	regulatory region nucleic acid binding
0.46	GO:0003713	transcription coactivator activity
0.46	GO:0008134	transcription factor binding
0.42	GO:0008013	beta-catenin binding
0.40	GO:0019899	enzyme binding
0.37	GO:0051427	hormone receptor binding
0.37	GO:0046982	protein heterodimerization activity
0.34	GO:0003682	chromatin binding

0.54	GO:0005634	nucleus
0.50	GO:0005667	transcription factor complex
0.44	GO:0000785	chromatin
0.42	GO:0070013	intracellular organelle lumen
0.36	GO:0032993	protein-DNA complex
0.33	GO:0005737	cytoplasm
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016020	membrane

tr|Q4H3A8|Q4H3A8_CIOIN
Transcription factor protein
Search

0.50	Transcription factor protein

0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression

0.64

GO:0043565

sequence-specific DNA binding

0.61

GO:0005634

nucleus

tr|Q4H3B1|Q4H3B1_CIOIN
Interferon regulatory factor like protein
Search

IRF-LIKE-6

0.87	interferon regulatory factor like protein isoform X1

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.40	GO:0006351	transcription, DNA-templated
0.40	GO:0014005	microglia development
0.40	GO:0045658	regulation of neutrophil differentiation
0.39	GO:0045649	regulation of macrophage differentiation
0.37	GO:0048702	embryonic neurocranium morphogenesis
0.36	GO:0045368	positive regulation of interleukin-13 biosynthetic process
0.36	GO:0045404	positive regulation of interleukin-4 biosynthetic process

0.76	GO:0044212	transcription regulatory region DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.34	GO:0016279	protein-lysine N-methyltransferase activity
0.34	GO:1990837	sequence-specific double-stranded DNA binding

0.41	GO:0005634	nucleus
0.34	GO:0000786	nucleosome
0.34	GO:0031974	membrane-enclosed lumen

0.34

GO:0016279

tr|Q4H3C1|Q4H3C1_CIOIN
IkappaB kinase (Fragment)
Search

0.55	Inhibitor of nuclear factor kappa B kinase subunit beta

0.76	GO:0007252	I-kappaB phosphorylation
0.58	GO:1903347	negative regulation of bicellular tight junction assembly
0.58	GO:0035509	negative regulation of myosin-light-chain-phosphatase activity
0.57	GO:1903140	regulation of establishment of endothelial barrier
0.56	GO:0070498	interleukin-1-mediated signaling pathway
0.56	GO:0033209	tumor necrosis factor-mediated signaling pathway
0.55	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.54	GO:0018105	peptidyl-serine phosphorylation
0.54	GO:0072659	protein localization to plasma membrane
0.54	GO:0030866	cortical actin cytoskeleton organization

0.77	GO:0008384	IkappaB kinase activity
0.56	GO:0097110	scaffold protein binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0019901	protein kinase binding
0.51	GO:0042803	protein homodimerization activity
0.50	GO:0046982	protein heterodimerization activity
0.34	GO:0000287	magnesium ion binding

0.48	GO:0005829	cytosol
0.44	GO:1902554	serine/threonine protein kinase complex
0.38	GO:0098857	membrane microdomain
0.37	GO:0035631	CD40 receptor complex
0.36	GO:0009898	cytoplasmic side of plasma membrane
0.36	GO:0005634	nucleus

0.77

EC:2.7.11.10

GO:0008384

tr|Q4H3C6|Q4H3C6_CIOIN
Transcription factor protein
Search

0.43	Transcription factor protein

0.66	GO:0007275	multicellular organism development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.48	GO:0061448	connective tissue development
0.46	GO:0006366	transcription by RNA polymerase II
0.45	GO:1902680	positive regulation of RNA biosynthetic process
0.45	GO:0009653	anatomical structure morphogenesis

0.65	GO:0043565	sequence-specific DNA binding
0.58	GO:0003700	DNA binding transcription factor activity
0.51	GO:0071837	HMG box domain binding
0.49	GO:0035326	enhancer binding
0.47	GO:0001012	RNA polymerase II regulatory region DNA binding
0.45	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.43	GO:0043233	organelle lumen
0.39	GO:0044446	intracellular organelle part

tr|Q4H3C8|Q4H3C8_CIOIN
Transcription factor protein (Fragment)
Search

0.66	Homeotic protein proboscipedia (Fragment)

0.62	GO:0007275	multicellular organism development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.39	GO:0060322	head development
0.38	GO:0060429	epithelium development
0.37	GO:0048857	neural nucleus development
0.37	GO:0048532	anatomical structure arrangement
0.36	GO:0048729	tissue morphogenesis
0.35	GO:1902680	positive regulation of RNA biosynthetic process

0.65	GO:0043565	sequence-specific DNA binding
0.55	GO:0003700	DNA binding transcription factor activity
0.34	GO:0004000	adenosine deaminase activity

0.61	GO:0005634	nucleus
0.35	GO:0005829	cytosol
0.35	GO:0043233	organelle lumen
0.34	GO:0044446	intracellular organelle part

0.34

EC:3.5.4.4

GO:0004000

tr|Q4H3C9|Q4H3C9_CIOIN
Transcription factor protein
Search

0.47	homeobox transcription factor Hox13

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.50	GO:0060526	prostate glandular acinus morphogenesis
0.50	GO:0060687	regulation of branching involved in prostate gland morphogenesis
0.50	GO:0060442	branching involved in prostate gland morphogenesis
0.49	GO:0060602	branch elongation of an epithelium
0.49	GO:0060571	morphogenesis of an epithelial fold
0.49	GO:0030539	male genitalia development
0.48	GO:0042733	embryonic digit morphogenesis

0.64	GO:0043565	sequence-specific DNA binding
0.48	GO:0035326	enhancer binding
0.47	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.46	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.45	GO:0001012	RNA polymerase II regulatory region DNA binding
0.45	GO:0003682	chromatin binding
0.44	GO:0003690	double-stranded DNA binding
0.33	GO:0005179	hormone activity

0.61	GO:0005634	nucleus
0.32	GO:0005576	extracellular region
0.30	GO:0016020	membrane

tr|Q4H3D0|Q4H3D0_CIOIN
Transcription factor protein
Search

0.45	transcription factor protein

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.49	GO:0042733	embryonic digit morphogenesis
0.47	GO:0001501	skeletal system development
0.47	GO:0007389	pattern specification process
0.36	GO:0006351	transcription, DNA-templated

0.65	GO:0043565	sequence-specific DNA binding
0.33	GO:0005515	protein binding
0.33	GO:0003700	DNA binding transcription factor activity

0.61	GO:0005634	nucleus
0.45	GO:0005667	transcription factor complex

tr|Q4H3D5|Q4H3D5_CIOIN
Nuclear receptor
Search

HNF4A

0.78	Hepatocyte nuclear factor 4 alpha

0.79	GO:0043401	steroid hormone mediated signaling pathway
0.67	GO:0030522	intracellular receptor signaling pathway
0.58	GO:0097659	nucleic acid-templated transcription
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0010467	gene expression
0.53	GO:2000189	positive regulation of cholesterol homeostasis
0.53	GO:0034645	cellular macromolecule biosynthetic process
0.52	GO:0055091	phospholipid homeostasis

0.80	GO:0003707	steroid hormone receptor activity
0.69	GO:0004879	nuclear receptor activity
0.65	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.51	GO:0001012	RNA polymerase II regulatory region DNA binding
0.51	GO:0001102	RNA polymerase II activating transcription factor binding
0.51	GO:0005504	fatty acid binding
0.50	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.49	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.49	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.44	GO:0070013	intracellular organelle lumen
0.41	GO:0044446	intracellular organelle part
0.37	GO:0005737	cytoplasm
0.34	GO:0005667	transcription factor complex

0.35

EC:3.1.2.2

GO:0016290

tr|Q4H3D9|Q4H3D9_CIOIN
Transcription factor protein
Search

HMG20B

0.68	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related

0.55	GO:0033234	negative regulation of protein sumoylation
0.53	GO:0035914	skeletal muscle cell differentiation
0.51	GO:0045666	positive regulation of neuron differentiation
0.36	GO:0016569	covalent chromatin modification
0.35	GO:0007049	cell cycle
0.35	GO:0007596	blood coagulation
0.34	GO:0006476	protein deacetylation
0.34	GO:0006351	transcription, DNA-templated
0.34	GO:0006338	chromatin remodeling
0.34	GO:1903506	regulation of nucleic acid-templated transcription

0.55	GO:0003677	DNA binding
0.48	GO:0046982	protein heterodimerization activity
0.34	GO:0004407	histone deacetylase activity
0.33	GO:0003700	DNA binding transcription factor activity

0.61	GO:0005634	nucleus
0.46	GO:0031974	membrane-enclosed lumen
0.42	GO:0044446	intracellular organelle part
0.36	GO:0005694	chromosome
0.33	GO:0043234	protein complex

0.34

EC:3.5.1.98

GO:0004407

tr|Q4H3E0|Q4H3E0_CIOIN
Transcription factor protein
Search

HMGB3

0.79	High mobility group box 1

0.54	GO:0032392	DNA geometric change
0.50	GO:0045578	negative regulation of B cell differentiation
0.48	GO:0045638	negative regulation of myeloid cell differentiation
0.37	GO:0045087	innate immune response
0.35	GO:0017055	negative regulation of RNA polymerase II transcriptional preinitiation complex assembly
0.35	GO:0008348	negative regulation of antimicrobial humoral response
0.35	GO:0007379	segment specification
0.35	GO:0035218	leg disc development
0.35	GO:0043388	positive regulation of DNA binding
0.34	GO:0006351	transcription, DNA-templated

0.64	GO:0000400	four-way junction DNA binding
0.64	GO:0008301	DNA binding, bending
0.39	GO:0003723	RNA binding
0.35	GO:0003690	double-stranded DNA binding
0.35	GO:0000405	bubble DNA binding
0.34	GO:0017025	TBP-class protein binding
0.34	GO:0003697	single-stranded DNA binding
0.32	GO:0046872	metal ion binding

0.61	GO:0005634	nucleus
0.36	GO:0005694	chromosome
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0005737	cytoplasm
0.32	GO:0044446	intracellular organelle part

tr|Q4H3E2|Q4H3E2_CIOIN
Ci-HTATSF1 protein (Fragment)
Search

HTATSF1

0.90	HIV Tat-specific factor 1

0.72	GO:0000398	mRNA splicing, via spliceosome
0.34	GO:0006351	transcription, DNA-templated
0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0006414	translational elongation
0.34	GO:0010468	regulation of gene expression
0.33	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:0019079	viral genome replication
0.32	GO:0006915	apoptotic process

0.59	GO:0003723	RNA binding
0.37	GO:0045296	cadherin binding
0.36	GO:0042802	identical protein binding
0.34	GO:0008528	G-protein coupled peptide receptor activity
0.32	GO:0043565	sequence-specific DNA binding
0.32	GO:0008270	zinc ion binding
0.32	GO:0003700	DNA binding transcription factor activity

0.47	GO:0005686	U2 snRNP
0.47	GO:0005684	U2-type spliceosomal complex
0.45	GO:0005654	nucleoplasm
0.38	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex
0.36	GO:0030054	cell junction
0.30	GO:0031224	intrinsic component of membrane

tr|Q4H3E8|Q4H3E8_CIOIN
Transcription factor protein
Search

0.54	Homeobox transcription factor

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.34	GO:0048033	heme o metabolic process
0.33	GO:0006783	heme biosynthetic process
0.33	GO:1902679	negative regulation of RNA biosynthetic process
0.33	GO:0007275	multicellular organism development

0.64	GO:0043565	sequence-specific DNA binding
0.36	GO:0003700	DNA binding transcription factor activity
0.34	GO:0008495	protoheme IX farnesyltransferase activity
0.34	GO:0004000	adenosine deaminase activity
0.34	GO:0042803	protein homodimerization activity
0.34	GO:0046982	protein heterodimerization activity

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.34

EC:2.5.1

GO:0008495

tr|Q4H3F0|Q4H3F0_CIOIN
Groucho
Search

0.79	Co-repressor protein groucho

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.40	GO:0045879	negative regulation of smoothened signaling pathway
0.39	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.39	GO:0051253	negative regulation of RNA metabolic process
0.39	GO:0010558	negative regulation of macromolecule biosynthetic process
0.39	GO:0031327	negative regulation of cellular biosynthetic process
0.39	GO:0042981	regulation of apoptotic process
0.38	GO:0007399	nervous system development

0.42	GO:0071906	CRD domain binding
0.42	GO:0070491	repressing transcription factor binding
0.41	GO:0003714	transcription corepressor activity
0.40	GO:0071837	HMG box domain binding
0.40	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.38	GO:0001104	RNA polymerase II transcription cofactor activity
0.37	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.36	GO:0003682	chromatin binding
0.34	GO:0016905	myosin heavy chain kinase activity
0.32	GO:0003677	DNA binding

0.61	GO:0005634	nucleus
0.37	GO:0043234	protein complex
0.35	GO:0044446	intracellular organelle part
0.33	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:2.7.11.7

GO:0016905

tr|Q4H3F3|Q4H3F3_CIOIN
Nuclear receptor
Search

GCNF

0.53	Nuclear receptor

0.75	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0030522	intracellular receptor signaling pathway
0.45	GO:0048609	multicellular organismal reproductive process
0.43	GO:0051254	positive regulation of RNA metabolic process
0.43	GO:0010557	positive regulation of macromolecule biosynthetic process
0.43	GO:0031328	positive regulation of cellular biosynthetic process

0.76	GO:0003707	steroid hormone receptor activity
0.64	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0001012	RNA polymerase II regulatory region DNA binding
0.51	GO:0003690	double-stranded DNA binding
0.41	GO:0035326	enhancer binding
0.41	GO:0042803	protein homodimerization activity
0.40	GO:0003682	chromatin binding
0.39	GO:0005543	phospholipid binding

0.61	GO:0005634	nucleus
0.53	GO:0005667	transcription factor complex
0.36	GO:0044446	intracellular organelle part

tr|Q4H3F5|Q4H3F5_CIOIN
Transcription factor protein (Fragment)
Search

0.21	Endothelial transcription factor GATA-2

0.63	GO:0030097	hemopoiesis
0.57	GO:0006355	regulation of transcription, DNA-templated
0.54	GO:1903708	positive regulation of hemopoiesis
0.54	GO:1902105	regulation of leukocyte differentiation
0.52	GO:0045597	positive regulation of cell differentiation
0.51	GO:0021514	ventral spinal cord interneuron differentiation
0.50	GO:0070345	negative regulation of fat cell proliferation
0.49	GO:2000977	regulation of forebrain neuron differentiation
0.49	GO:0010725	regulation of primitive erythrocyte differentiation
0.49	GO:0021902	commitment of neuronal cell to specific neuron type in forebrain

0.65	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0044212	transcription regulatory region DNA binding
0.52	GO:0003690	double-stranded DNA binding
0.49	GO:0070742	C2H2 zinc finger domain binding
0.48	GO:0003682	chromatin binding
0.47	GO:0008134	transcription factor binding
0.36	GO:0003707	steroid hormone receptor activity
0.34	GO:0005134	interleukin-2 receptor binding

0.54	GO:0005634	nucleus
0.44	GO:0005667	transcription factor complex
0.42	GO:0070013	intracellular organelle lumen
0.39	GO:0044446	intracellular organelle part
0.33	GO:0005694	chromosome
0.30	GO:0044425	membrane part

tr|Q4H3F7|Q4H3F7_CIOIN
GA repeat binding protein alpha homolog
Search

0.69	GA binding protein transcription factor alpha subunit

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.52	GO:0045653	negative regulation of megakaryocyte differentiation
0.51	GO:1903351	cellular response to dopamine
0.46	GO:0006366	transcription by RNA polymerase II
0.46	GO:0001701	in utero embryonic development
0.45	GO:1902680	positive regulation of RNA biosynthetic process
0.44	GO:1902679	negative regulation of RNA biosynthetic process
0.43	GO:0030154	cell differentiation

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.49	GO:0033613	activating transcription factor binding
0.47	GO:0001012	RNA polymerase II regulatory region DNA binding
0.46	GO:0003682	chromatin binding
0.45	GO:0046982	protein heterodimerization activity
0.45	GO:0003690	double-stranded DNA binding
0.34	GO:0003713	transcription coactivator activity

0.61	GO:0005634	nucleus
0.45	GO:0000785	chromatin
0.43	GO:0031974	membrane-enclosed lumen
0.30	GO:0016020	membrane

tr|Q4H3G2|Q4H3G2_CIOIN
Nuclear receptor
Search

NR1H4

0.84	Bile acid receptor

0.79	GO:0030522	intracellular receptor signaling pathway
0.78	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0097659	nucleic acid-templated transcription
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0010467	gene expression
0.53	GO:0034645	cellular macromolecule biosynthetic process
0.49	GO:1905695	positive regulation of phosphatidic acid biosynthetic process
0.49	GO:2001250	positive regulation of ammonia assimilation cycle

0.85	GO:0004887	thyroid hormone receptor activity
0.80	GO:0003707	steroid hormone receptor activity
0.65	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.49	GO:1902122	chenodeoxycholic acid binding
0.48	GO:0038181	bile acid receptor activity
0.47	GO:0046965	retinoid X receptor binding
0.46	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.46	GO:0035326	enhancer binding
0.46	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding

0.61	GO:0005634	nucleus
0.46	GO:0000791	euchromatin
0.41	GO:0070013	intracellular organelle lumen
0.33	GO:0005856	cytoskeleton

tr|Q4H3H4|Q4H3H4_CIOIN
Fringe
Search

MFNG

0.77	MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

0.56	GO:0007389	pattern specification process
0.52	GO:0008593	regulation of Notch signaling pathway
0.51	GO:0002315	marginal zone B cell differentiation
0.51	GO:0036066	protein O-linked fucosylation
0.49	GO:0032092	positive regulation of protein binding
0.46	GO:0009967	positive regulation of signal transduction
0.44	GO:0036099	female germ-line stem cell population maintenance
0.43	GO:0008587	imaginal disc-derived wing margin morphogenesis
0.43	GO:0007480	imaginal disc-derived leg morphogenesis
0.43	GO:0007293	germarium-derived egg chamber formation

0.65	GO:0016757	transferase activity, transferring glycosyl groups
0.41	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding
0.33	GO:0003700	DNA binding transcription factor activity
0.32	GO:0004222	metalloendopeptidase activity

0.57	GO:0030173	integral component of Golgi membrane
0.43	GO:0005797	Golgi medial cisterna
0.39	GO:0005783	endoplasmic reticulum
0.33	GO:0005615	extracellular space
0.33	GO:0005634	nucleus

0.65

GO:0016757

tr|Q4H3I6|Q4H3I6_CIOIN
Transcription factor protein
Search

0.46	transcription factor protein isoform X1

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.52	GO:0009653	anatomical structure morphogenesis
0.49	GO:0030154	cell differentiation
0.49	GO:0048839	inner ear development
0.48	GO:0048568	embryonic organ development
0.47	GO:1902680	positive regulation of RNA biosynthetic process
0.47	GO:0006366	transcription by RNA polymerase II
0.39	GO:0008544	epidermis development

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.48	GO:0001012	RNA polymerase II regulatory region DNA binding
0.46	GO:0003690	double-stranded DNA binding
0.34	GO:0008301	DNA binding, bending

0.61	GO:0005634	nucleus
0.44	GO:0031974	membrane-enclosed lumen
0.41	GO:0043232	intracellular non-membrane-bounded organelle
0.40	GO:0044446	intracellular organelle part

tr|Q4H3J7|Q4H3J7_CIOIN
Transcription factor protein
Search

0.56	Fork head orthologue

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.45	GO:0042593	glucose homeostasis
0.44	GO:0007283	spermatogenesis
0.44	GO:0009653	anatomical structure morphogenesis
0.44	GO:0009267	cellular response to starvation
0.43	GO:1902680	positive regulation of RNA biosynthetic process
0.42	GO:0055082	cellular chemical homeostasis
0.42	GO:0030154	cell differentiation

0.72	GO:0019904	protein domain specific binding
0.69	GO:0008134	transcription factor binding
0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.44	GO:0044212	transcription regulatory region DNA binding
0.32	GO:0046872	metal ion binding

0.61	GO:0005634	nucleus
0.43	GO:0015629	actin cytoskeleton
0.41	GO:0043233	organelle lumen
0.38	GO:0044446	intracellular organelle part
0.34	GO:0005902	microvillus

tr|Q4H3J8|Q4H3J8_CIOIN
Ci-Fhl1/2/3 protein
Search

0.11	Putative adaptor protein enigma

0.34

GO:0045892

negative regulation of transcription, DNA-templated

0.54

GO:0046872

metal ion binding

tr|Q4H3J9|Q4H3J9_CIOIN
Transcription factor protein
Search

FOS

0.49	transcription factor protein isoform X3

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.52	GO:0071277	cellular response to calcium ion
0.48	GO:0006366	transcription by RNA polymerase II
0.47	GO:0045893	positive regulation of transcription, DNA-templated
0.41	GO:0009612	response to mechanical stimulus
0.40	GO:0051412	response to corticosterone
0.39	GO:0043278	response to morphine
0.39	GO:0032570	response to progesterone
0.39	GO:0071495	cellular response to endogenous stimulus
0.39	GO:0051591	response to cAMP

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.48	GO:0001067	regulatory region nucleic acid binding
0.38	GO:0070412	R-SMAD binding
0.37	GO:0001102	RNA polymerase II activating transcription factor binding
0.37	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.36	GO:0003682	chromatin binding
0.36	GO:0046982	protein heterodimerization activity

0.53	GO:0005634	nucleus
0.48	GO:0005667	transcription factor complex
0.44	GO:0031974	membrane-enclosed lumen
0.41	GO:0044446	intracellular organelle part
0.36	GO:0032993	protein-DNA complex
0.35	GO:0005783	endoplasmic reticulum
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

tr|Q4H3K0|Q4H3K0_CIOIN
Transcription factor protein (Fragment)
Search

0.59	Homeobox-containing protein 1

0.73	GO:0045893	positive regulation of transcription, DNA-templated
0.48	GO:0031018	endocrine pancreas development
0.47	GO:0035623	renal glucose absorption
0.46	GO:0048341	paraxial mesoderm formation
0.45	GO:0006699	bile acid biosynthetic process
0.45	GO:0045453	bone resorption
0.45	GO:0043691	reverse cholesterol transport
0.45	GO:0030073	insulin secretion
0.45	GO:0015721	bile acid and bile salt transport
0.45	GO:0046323	glucose import

0.57	GO:0043565	sequence-specific DNA binding
0.44	GO:0001012	RNA polymerase II regulatory region DNA binding
0.43	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.42	GO:0003690	double-stranded DNA binding
0.42	GO:0042803	protein homodimerization activity
0.42	GO:0046982	protein heterodimerization activity
0.36	GO:0001221	transcription cofactor binding
0.36	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.44	GO:0001750	photoreceptor outer segment
0.42	GO:0005667	transcription factor complex
0.35	GO:0005737	cytoplasm

tr|Q4H3K3|Q4H3K3_CIOIN
Transcription factor protein
Search

0.46	transcription factor protein

0.62	GO:0035855	megakaryocyte development
0.57	GO:0006357	regulation of transcription by RNA polymerase II
0.57	GO:0008015	blood circulation
0.56	GO:0009887	animal organ morphogenesis
0.55	GO:0010628	positive regulation of gene expression
0.55	GO:0006366	transcription by RNA polymerase II
0.54	GO:1903508	positive regulation of nucleic acid-templated transcription
0.41	GO:0048665	neuron fate specification
0.41	GO:0042551	neuron maturation
0.38	GO:0060218	hematopoietic stem cell differentiation

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.60	GO:0035326	enhancer binding
0.56	GO:0001012	RNA polymerase II regulatory region DNA binding
0.55	GO:0003682	chromatin binding
0.53	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.52	GO:0031974	membrane-enclosed lumen
0.51	GO:0005829	cytosol
0.46	GO:0044446	intracellular organelle part

sp|Q4H3K6|FGFR_CIOIN
Fibroblast growth factor receptor
Search

0.54	Fibroblast growth factor receptor

0.81	GO:0008543	fibroblast growth factor receptor signaling pathway
0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.77	GO:0008284	positive regulation of cell proliferation
0.53	GO:0051054	positive regulation of DNA metabolic process
0.53	GO:0046777	protein autophosphorylation
0.52	GO:0043410	positive regulation of MAPK cascade
0.51	GO:2000830	positive regulation of parathyroid hormone secretion
0.50	GO:0090272	negative regulation of fibroblast growth factor production
0.50	GO:0070857	regulation of bile acid biosynthetic process
0.50	GO:0010715	regulation of extracellular matrix disassembly

0.85	GO:0005007	fibroblast growth factor-activated receptor activity
0.56	GO:0017134	fibroblast growth factor binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0090722	receptor-receptor interaction
0.48	GO:1901681	sulfur compound binding
0.44	GO:0042803	protein homodimerization activity
0.37	GO:0005018	platelet-derived growth factor alpha-receptor activity

0.46	GO:0030133	transport vesicle
0.45	GO:0005911	cell-cell junction
0.45	GO:0043235	receptor complex
0.44	GO:0005783	endoplasmic reticulum
0.44	GO:0005794	Golgi apparatus
0.44	GO:0005730	nucleolus
0.43	GO:0005887	integral component of plasma membrane
0.38	GO:0005768	endosome
0.34	GO:0005576	extracellular region
0.33	GO:0005829	cytosol

0.36	EC:2.7.1.153	GO:0046934
0.36	KEGG:R04545	GO:0046934

tr|Q4H3L5|Q4H3L5_CIOIN
Mitogen-activated protein kinase
Search

MAPK1

0.58	Mitogen-activated protein kinase

0.80	GO:0000165	MAPK cascade
0.56	GO:0060440	trachea formation
0.56	GO:0042473	outer ear morphogenesis
0.56	GO:0061308	cardiac neural crest cell development involved in heart development
0.56	GO:0060020	Bergmann glial cell differentiation
0.55	GO:1903351	cellular response to dopamine
0.55	GO:0070849	response to epidermal growth factor
0.55	GO:1904355	positive regulation of telomere capping
0.54	GO:0030878	thyroid gland development
0.54	GO:0060425	lung morphogenesis

0.82	GO:0004707	MAP kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.55	GO:0004708	MAP kinase kinase activity
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0001784	phosphotyrosine residue binding
0.52	GO:0019902	phosphatase binding
0.50	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity
0.48	GO:0042802	identical protein binding

0.55	GO:0031143	pseudopodium
0.48	GO:0005829	cytosol
0.47	GO:0005901	caveola
0.46	GO:0005925	focal adhesion
0.45	GO:0005770	late endosome
0.45	GO:0005769	early endosome
0.45	GO:0005634	nucleus
0.43	GO:0005739	mitochondrion
0.43	GO:0005794	Golgi apparatus
0.42	GO:0005856	cytoskeleton

0.82	EC:2.7.11.24	GO:0004707
0.82	KEGG:R00162	GO:0004707

tr|Q4H3L6|Q4H3L6_CIOIN
Transcription factor protein
Search

0.45	transcription factor protein

0.66	GO:0000122	negative regulation of transcription by RNA polymerase II
0.48	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus
0.46	GO:0030154	cell differentiation
0.45	GO:0008285	negative regulation of cell proliferation
0.35	GO:0006351	transcription, DNA-templated
0.34	GO:0051103	DNA ligation involved in DNA repair
0.33	GO:0071897	DNA biosynthetic process
0.33	GO:0006468	protein phosphorylation
0.33	GO:0006260	DNA replication
0.33	GO:0006310	DNA recombination

0.68	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.65	GO:0043565	sequence-specific DNA binding
0.48	GO:0017151	DEAD/H-box RNA helicase binding
0.44	GO:0001012	RNA polymerase II regulatory region DNA binding
0.43	GO:0003714	transcription corepressor activity
0.43	GO:0003690	double-stranded DNA binding
0.34	GO:0003910	DNA ligase (ATP) activity
0.33	GO:0004672	protein kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding

0.61	GO:0005634	nucleus
0.45	GO:0017053	transcriptional repressor complex
0.43	GO:0000785	chromatin
0.41	GO:0031974	membrane-enclosed lumen
0.30	GO:0016020	membrane

0.34

EC:6.5.1.1

GO:0003910

tr|Q4H3L7|Q4H3L7_CIOIN
Transcription factor protein (Fragment)
Search

0.58	Transcription factor protein (Fragment)

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.42	GO:0030154	cell differentiation
0.37	GO:1902679	negative regulation of RNA biosynthetic process
0.36	GO:0007275	multicellular organism development
0.36	GO:0021700	developmental maturation
0.36	GO:0048518	positive regulation of biological process
0.35	GO:0007154	cell communication
0.35	GO:0050896	response to stimulus

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.38	GO:0003714	transcription corepressor activity
0.38	GO:0005230	extracellular ligand-gated ion channel activity
0.36	GO:0099600	transmembrane receptor activity
0.36	GO:0038023	signaling receptor activity
0.35	GO:0001012	RNA polymerase II regulatory region DNA binding
0.34	GO:0001085	RNA polymerase II transcription factor binding
0.34	GO:0003690	double-stranded DNA binding
0.34	GO:0005509	calcium ion binding

0.61	GO:0005634	nucleus
0.35	GO:0043233	organelle lumen
0.34	GO:0044446	intracellular organelle part
0.32	GO:0044444	cytoplasmic part
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.32	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

0.33

EC:3.1.1

GO:0016298

tr|Q4H3L8|Q4H3L8_CIOIN
Ephrin
Search

0.69	ephrin precursor

0.70	GO:0048013	ephrin receptor signaling pathway
0.64	GO:0031295	T cell costimulation
0.62	GO:0007411	axon guidance
0.54	GO:0007628	adult walking behavior
0.54	GO:0050771	negative regulation of axonogenesis
0.53	GO:0008038	neuron recognition
0.53	GO:0001755	neural crest cell migration
0.53	GO:0042102	positive regulation of T cell proliferation
0.52	GO:0009880	embryonic pattern specification
0.42	GO:0021654	rhombomere boundary formation

0.72	GO:0046875	ephrin receptor binding
0.36	GO:0005005	transmembrane-ephrin receptor activity
0.36	GO:0104005	hijacked molecular function
0.34	GO:0003777	microtubule motor activity
0.33	GO:0016887	ATPase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.51	GO:0045121	membrane raft
0.46	GO:0005886	plasma membrane
0.43	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.36	GO:0045202	synapse
0.35	GO:0030286	dynein complex
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0016887

tr|Q4H3M1|Q4H3M1_CIOIN
Ephrin
Search

0.70	ephrin precursor

0.71	GO:0048013	ephrin receptor signaling pathway
0.58	GO:0007409	axonogenesis
0.58	GO:0097485	neuron projection guidance
0.38	GO:1990138	neuron projection extension
0.38	GO:0071526	semaphorin-plexin signaling pathway
0.37	GO:0035023	regulation of Rho protein signal transduction
0.37	GO:0006508	proteolysis
0.37	GO:0006898	receptor-mediated endocytosis
0.36	GO:0065009	regulation of molecular function
0.35	GO:0005975	carbohydrate metabolic process

0.73	GO:0046875	ephrin receptor binding
0.38	GO:0017154	semaphorin receptor activity
0.38	GO:0005044	scavenger receptor activity
0.38	GO:0004556	alpha-amylase activity
0.38	GO:0004175	endopeptidase activity
0.37	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.36	GO:0005509	calcium ion binding
0.36	GO:0008237	metallopeptidase activity
0.36	GO:0017171	serine hydrolase activity
0.35	GO:0008270	zinc ion binding

0.44	GO:0005886	plasma membrane
0.38	GO:0016607	nuclear speck
0.36	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.38

EC:3.2.1.1

GO:0004556

tr|Q4H3M8|Q4H3M8_CIOIN
Transcription factor protein (Fragment)
Search

0.66	Empty spiracles homeobox 3

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0007420	brain development
0.53	GO:0030182	neuron differentiation
0.49	GO:0061351	neural precursor cell proliferation
0.48	GO:0009952	anterior/posterior pattern specification
0.48	GO:0072001	renal system development
0.47	GO:0016477	cell migration
0.46	GO:0000904	cell morphogenesis involved in differentiation

0.65	GO:0043565	sequence-specific DNA binding
0.33	GO:0005515	protein binding

0.61

GO:0005634

nucleus

tr|Q4H3N0|Q4H3N0_CIOIN
Transcription factor protein
Search

0.50	Transcription factor protein

0.72	GO:0030154	cell differentiation
0.71	GO:0006357	regulation of transcription by RNA polymerase II

0.73	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.65	GO:0043565	sequence-specific DNA binding

0.61

GO:0005634

nucleus

tr|Q4H3N7|Q4H3N7_CIOIN
Transcription factor protein
Search

E12/E47

0.53	transcription factor protein isoform X3

0.52	GO:0045666	positive regulation of neuron differentiation
0.49	GO:0045944	positive regulation of transcription by RNA polymerase II
0.46	GO:0006366	transcription by RNA polymerase II
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation
0.34	GO:0033152	immunoglobulin V(D)J recombination
0.34	GO:0007517	muscle organ development
0.34	GO:0051091	positive regulation of DNA binding transcription factor activity
0.34	GO:0000122	negative regulation of transcription by RNA polymerase II
0.33	GO:0006955	immune response

0.68	GO:0046983	protein dimerization activity
0.54	GO:0043425	bHLH transcription factor binding
0.52	GO:0070888	E-box binding
0.49	GO:0046332	SMAD binding
0.48	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.44	GO:0042802	identical protein binding
0.38	GO:0071837	HMG box domain binding
0.38	GO:0035497	cAMP response element binding
0.35	GO:0070644	vitamin D response element binding
0.34	GO:0031435	mitogen-activated protein kinase kinase kinase binding

0.49	GO:0005667	transcription factor complex
0.48	GO:0016607	nuclear speck
0.46	GO:0000790	nuclear chromatin
0.37	GO:0005737	cytoplasm

sp|Q4H3N8|ENY2_CIOIN
Transcription and mRNA export factor ENY2
Search

E(Y)2

0.76	Enhancer of yellow 2 transcription factor

0.81	GO:0016578	histone deubiquitination
0.81	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.76	GO:0051028	mRNA transport
0.76	GO:0006368	transcription elongation from RNA polymerase II promoter
0.75	GO:0006405	RNA export from nucleus
0.73	GO:0045893	positive regulation of transcription, DNA-templated
0.42	GO:0006357	regulation of transcription by RNA polymerase II

0.79	GO:0003713	transcription coactivator activity
0.44	GO:0003682	chromatin binding

0.83	GO:0071819	DUBm complex
0.82	GO:0070390	transcription export complex 2
0.80	GO:0000124	SAGA complex
0.78	GO:0005643	nuclear pore
0.38	GO:0000932	P-body
0.30	GO:0016020	membrane

tr|Q4H3P2|Q4H3P2_CIOIN
Dual specificity phosphatase
Search

0.45	Dual specificity phosphatase

0.81	GO:0000188	inactivation of MAPK activity
0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.35	GO:0045208	MAPK phosphatase export from nucleus
0.35	GO:0045204	MAPK export from nucleus
0.35	GO:0016310	phosphorylation
0.32	GO:0006397	mRNA processing
0.32	GO:0006518	peptide metabolic process
0.32	GO:0043604	amide biosynthetic process
0.32	GO:1901566	organonitrogen compound biosynthetic process
0.32	GO:0009059	macromolecule biosynthetic process

0.82	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity
0.75	GO:0004725	protein tyrosine phosphatase activity
0.35	GO:0016301	kinase activity
0.35	GO:0005515	protein binding
0.33	GO:0003735	structural constituent of ribosome
0.31	GO:0003676	nucleic acid binding

0.46	GO:0005654	nucleoplasm
0.38	GO:0005737	cytoplasm
0.33	GO:0097708	intracellular vesicle
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.32	GO:0043232	intracellular non-membrane-bounded organelle

0.82

EC:3.1.3

GO:0017017

sp|Q4H3P5|DRI_CIOIN
Protein dead ringer homolog
Search

CI-DRIL1/2

0.46	AT-rich interactive domain-containing protein 3B

0.37	GO:0006366	transcription by RNA polymerase II
0.37	GO:0045944	positive regulation of transcription by RNA polymerase II

0.55	GO:0003677	DNA binding
0.38	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.37	GO:0001067	regulatory region nucleic acid binding
0.36	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.36	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.34	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part

tr|Q4H3Q3|Q4H3Q3_CIOIN
Dickkopf
Search

0.96

Dickkopf

tr|Q4H3R0|Q4H3R0_CIOIN
DAN
Search

0.70	GO:0010469	regulation of receptor activity
0.67	GO:0048263	determination of dorsal identity
0.64	GO:0030514	negative regulation of BMP signaling pathway
0.62	GO:0090291	negative regulation of osteoclast proliferation
0.62	GO:0090191	negative regulation of branching involved in ureteric bud morphogenesis
0.62	GO:1900086	positive regulation of peptidyl-tyrosine autophosphorylation
0.62	GO:0003257	positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
0.61	GO:1900155	negative regulation of bone trabecula formation
0.61	GO:0060676	ureteric bud formation
0.61	GO:1900158	negative regulation of bone mineralization involved in bone maturation

0.72	GO:0005125	cytokine activity
0.66	GO:0036122	BMP binding
0.62	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity
0.62	GO:0043184	vascular endothelial growth factor receptor 2 binding
0.57	GO:0042803	protein homodimerization activity
0.48	GO:0008201	heparin binding
0.39	GO:0016015	morphogen activity
0.36	GO:0043395	heparan sulfate proteoglycan binding

0.68	GO:0005615	extracellular space
0.53	GO:0009986	cell surface
0.30	GO:0016020	membrane

tr|Q4H3R5|Q4H3R5_CIOIN
Transcription factor protein
Search

CREM

0.86	cAMP responsive element modulator a

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.46	GO:1902679	negative regulation of RNA biosynthetic process
0.43	GO:0006687	glycosphingolipid metabolic process
0.42	GO:0007283	spermatogenesis
0.41	GO:1902680	positive regulation of RNA biosynthetic process
0.38	GO:0048384	retinoic acid receptor signaling pathway
0.38	GO:0042752	regulation of circadian rhythm
0.37	GO:0048511	rhythmic process

0.60	GO:0003700	DNA binding transcription factor activity
0.54	GO:0003677	DNA binding
0.48	GO:0001067	regulatory region nucleic acid binding
0.35	GO:0008140	cAMP response element binding protein binding

0.60	GO:0005634	nucleus
0.41	GO:0005667	transcription factor complex
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|Q4H3S1|Q4H3S1_CIOIN
Nuclear receptor
Search

NR2F1

0.80	Ovalbumin upstream promoter-transcription factor I

0.80	GO:0030522	intracellular receptor signaling pathway
0.79	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.47	GO:0001944	vasculature development
0.46	GO:0060839	endothelial cell fate commitment
0.46	GO:0051253	negative regulation of RNA metabolic process
0.46	GO:0010558	negative regulation of macromolecule biosynthetic process

0.82	GO:0004879	nuclear receptor activity
0.80	GO:0003707	steroid hormone receptor activity
0.64	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.47	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.45	GO:0001012	RNA polymerase II regulatory region DNA binding
0.43	GO:0001972	retinoic acid binding
0.43	GO:0003690	double-stranded DNA binding
0.40	GO:0042803	protein homodimerization activity
0.34	GO:0003713	transcription coactivator activity

0.61	GO:0005634	nucleus
0.45	GO:0005829	cytosol
0.44	GO:0070013	intracellular organelle lumen
0.40	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

tr|Q4H3S2|Q4H3S2_CIOIN
Core-binding factor, b subunit
Search

0.84	Runx transcription factor dimeric partner CBF-beta

0.57	GO:2001141	regulation of RNA biosynthetic process
0.48	GO:0035206	regulation of hemocyte proliferation
0.37	GO:0048769	sarcomerogenesis
0.36	GO:0048513	animal organ development
0.36	GO:0045214	sarcomere organization
0.36	GO:0060047	heart contraction
0.35	GO:0002520	immune system development
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression

0.79	GO:0003713	transcription coactivator activity
0.37	GO:0046982	protein heterodimerization activity
0.36	GO:0008134	transcription factor binding
0.33	GO:0003677	DNA binding

0.61	GO:0005634	nucleus
0.36	GO:0030018	Z disc
0.35	GO:0005667	transcription factor complex
0.33	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

tr|Q4H3S6|Q4H3S6_CIOIN
Ci-CNOT7/8 protein
Search

CNOT7

0.86	CCR4-NOT transcription complex subunit 7

0.55	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
0.54	GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
0.52	GO:0045070	positive regulation of viral genome replication
0.52	GO:0042509	regulation of tyrosine phosphorylation of STAT protein
0.51	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic
0.51	GO:0033962	cytoplasmic mRNA processing body assembly
0.50	GO:0008285	negative regulation of cell proliferation
0.49	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening
0.49	GO:0008284	positive regulation of cell proliferation
0.49	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA

0.55	GO:0004535	poly(A)-specific ribonuclease activity
0.51	GO:0001191	transcriptional repressor activity, RNA polymerase II transcription factor binding
0.51	GO:0003676	nucleic acid binding
0.46	GO:0008134	transcription factor binding
0.35	GO:0046872	metal ion binding
0.33	GO:0004871	signal transducer activity
0.33	GO:0003700	DNA binding transcription factor activity

0.55	GO:0075341	host cell PML body
0.53	GO:0030014	CCR4-NOT complex
0.51	GO:0000932	P-body
0.49	GO:0016607	nuclear speck
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.55

EC:3.1.13.4

GO:0004535

tr|Q4H3S8|Q4H3S8_CIOIN
Cockayne syndrome 1 homolog
Search

ERCC8

0.91	Cockayne syndrome WD repeat protein CSA

0.83	GO:0051865	protein autoubiquitination
0.82	GO:0010165	response to X-ray
0.79	GO:0000209	protein polyubiquitination
0.79	GO:0009411	response to UV
0.78	GO:0006283	transcription-coupled nucleotide-excision repair
0.75	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.69	GO:0006979	response to oxidative stress
0.50	GO:0045739	positive regulation of DNA repair
0.48	GO:0010996	response to auditory stimulus
0.44	GO:0014070	response to organic cyclic compound

0.73	GO:0032403	protein complex binding
0.71	GO:0004842	ubiquitin-protein transferase activity
0.40	GO:0003678	DNA helicase activity
0.40	GO:0008094	DNA-dependent ATPase activity
0.40	GO:0009922	fatty acid elongase activity
0.39	GO:0102756	very-long-chain 3-ketoacyl-CoA synthase activity
0.39	GO:0102338	3-oxo-lignoceronyl-CoA synthase activity
0.39	GO:0102336	3-oxo-arachidoyl-CoA synthase activity
0.39	GO:0102337	3-oxo-cerotoyl-CoA synthase activity
0.33	GO:0004674	protein serine/threonine kinase activity

0.84	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex
0.83	GO:0000109	nucleotide-excision repair complex
0.82	GO:0016363	nuclear matrix
0.47	GO:0043204	perikaryon
0.37	GO:0005654	nucleoplasm
0.37	GO:0005783	endoplasmic reticulum
0.30	GO:0016020	membrane

0.39	EC:2.3.1.199	GO:0102338
0.71	KEGG:R03876	GO:0004842

tr|Q4H3T3|Q4H3T3_CIOIN
Ci-CIR protein
Search

CIR1

0.84	Corepressor interacting with RBPJ

0.60	GO:0045892	negative regulation of transcription, DNA-templated
0.45	GO:0048477	oogenesis
0.45	GO:0022900	electron transport chain
0.44	GO:0008380	RNA splicing
0.42	GO:0006397	mRNA processing
0.42	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.42	GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.39	GO:0006357	regulation of transcription by RNA polymerase II
0.39	GO:0006351	transcription, DNA-templated
0.37	GO:0000028	ribosomal small subunit assembly

0.64	GO:0019901	protein kinase binding
0.46	GO:0043621	protein self-association
0.46	GO:0020037	heme binding
0.45	GO:0009055	electron transfer activity
0.42	GO:0046872	metal ion binding
0.40	GO:0043021	ribonucleoprotein complex binding
0.39	GO:0042826	histone deacetylase binding
0.39	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.38	GO:0003714	transcription corepressor activity
0.37	GO:0030515	snoRNA binding

0.67	GO:0000118	histone deacetylase complex
0.65	GO:0016607	nuclear speck
0.64	GO:0005813	centrosome
0.51	GO:0043234	protein complex
0.42	GO:0030684	preribosome
0.41	GO:0005730	nucleolus
0.35	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

tr|Q4H3U1|Q4H3U1_CIOIN
Transcription factor BTF3
Search

BTF3L4

0.78	Transcription factor BTF3

0.62	GO:0009792	embryo development ending in birth or egg hatching
0.43	GO:0015031	protein transport
0.42	GO:0006366	transcription by RNA polymerase II
0.41	GO:0043066	negative regulation of apoptotic process
0.40	GO:2001141	regulation of RNA biosynthetic process
0.40	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.40	GO:0010468	regulation of gene expression
0.39	GO:0006364	rRNA processing
0.37	GO:0006518	peptide metabolic process
0.37	GO:0043604	amide biosynthetic process

0.42	GO:0005515	protein binding
0.41	GO:0003723	RNA binding
0.38	GO:0003735	structural constituent of ribosome

0.58	GO:0005829	cytosol
0.43	GO:0005634	nucleus
0.40	GO:0043232	intracellular non-membrane-bounded organelle
0.39	GO:0031974	membrane-enclosed lumen
0.37	GO:0005739	mitochondrion
0.37	GO:0030529	intracellular ribonucleoprotein complex
0.37	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

tr|Q4H3V8|Q4H3V8_CIOIN
Transcription factor protein
Search

0.45	transcription factor protein

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.45	GO:0035074	pupation
0.44	GO:0035073	pupariation
0.43	GO:0007591	molting cycle, chitin-based cuticle
0.43	GO:0036499	PERK-mediated unfolded protein response
0.42	GO:0007552	metamorphosis
0.42	GO:0006641	triglyceride metabolic process
0.41	GO:0042594	response to starvation

0.61	GO:0003700	DNA binding transcription factor activity
0.43	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.43	GO:0001105	RNA polymerase II transcription coactivator activity
0.43	GO:0001102	RNA polymerase II activating transcription factor binding
0.36	GO:0046982	protein heterodimerization activity

0.40	GO:0005634	nucleus
0.40	GO:0030176	integral component of endoplasmic reticulum membrane

tr|Q4H3W1|Q4H3W1_CIOIN
Transcription factor protein
Search

0.46	transcription factor protein isoform X1

0.66	GO:0006357	regulation of transcription by RNA polymerase II
0.55	GO:0032915	positive regulation of transforming growth factor beta2 production
0.54	GO:0110024	positive regulation of cardiac muscle myoblast proliferation
0.53	GO:0060612	adipose tissue development
0.52	GO:1902110	positive regulation of mitochondrial membrane permeability involved in apoptotic process
0.52	GO:0003151	outflow tract morphogenesis
0.51	GO:0045444	fat cell differentiation
0.51	GO:0031573	intra-S DNA damage checkpoint
0.50	GO:0016525	negative regulation of angiogenesis
0.49	GO:0051091	positive regulation of DNA binding transcription factor activity

0.61	GO:0003700	DNA binding transcription factor activity
0.52	GO:0008140	cAMP response element binding protein binding
0.51	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.51	GO:0035497	cAMP response element binding
0.51	GO:0001102	RNA polymerase II activating transcription factor binding
0.49	GO:0004402	histone acetyltransferase activity
0.48	GO:0003682	chromatin binding
0.48	GO:0019901	protein kinase binding
0.36	GO:0046982	protein heterodimerization activity
0.34	GO:0003713	transcription coactivator activity

0.58	GO:0005634	nucleus
0.51	GO:0035861	site of double-strand break
0.48	GO:0005741	mitochondrial outer membrane
0.44	GO:0070013	intracellular organelle lumen
0.33	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)
0.30	GO:0016021	integral component of membrane

0.49

GO:0004402

tr|Q4H3W6|Q4H3W6_CIOIN
Adenomatosis polyposis coli (Fragment)
Search

0.84	Adenomatosis polyposis coli (Fragment)

0.83	GO:0030178	negative regulation of Wnt signaling pathway
0.77	GO:0016055	Wnt signaling pathway

0.84

GO:0008013

beta-catenin binding

tr|Q4H3W9|Q4H3W9_CIOIN
Transcription factor protein
Search

TFAP2A

0.75	Transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0042472	inner ear morphogenesis
0.51	GO:0043010	camera-type eye development
0.51	GO:0070172	positive regulation of tooth mineralization
0.50	GO:0048646	anatomical structure formation involved in morphogenesis
0.49	GO:0071281	cellular response to iron ion
0.49	GO:2000378	negative regulation of reactive oxygen species metabolic process
0.49	GO:0030501	positive regulation of bone mineralization

0.61	GO:0003700	DNA binding transcription factor activity
0.50	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.49	GO:0001047	core promoter binding
0.47	GO:0000987	proximal promoter sequence-specific DNA binding
0.46	GO:0003713	transcription coactivator activity
0.44	GO:0046983	protein dimerization activity
0.36	GO:0003682	chromatin binding
0.35	GO:0001106	RNA polymerase II transcription corepressor activity
0.35	GO:0001158	enhancer sequence-specific DNA binding
0.35	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding

0.61	GO:0005634	nucleus
0.45	GO:0005813	centrosome
0.43	GO:0043233	organelle lumen
0.43	GO:0005794	Golgi apparatus
0.42	GO:0005829	cytosol
0.35	GO:0005739	mitochondrion
0.33	GO:0005667	transcription factor complex
0.32	GO:0005840	ribosome
0.30	GO:0016020	membrane

tr|Q4VYB1|Q4VYB1_CIOIN
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase
Search

B3GAT3

0.76	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase

0.74	GO:0009101	glycoprotein biosynthetic process
0.74	GO:0043413	macromolecule glycosylation
0.60	GO:0036211	protein modification process
0.59	GO:0050654	chondroitin sulfate proteoglycan metabolic process
0.55	GO:0044267	cellular protein metabolic process
0.54	GO:0030201	heparan sulfate proteoglycan metabolic process
0.51	GO:0050655	dermatan sulfate proteoglycan metabolic process
0.50	GO:1903510	mucopolysaccharide metabolic process
0.48	GO:0090316	positive regulation of intracellular protein transport
0.47	GO:0043666	regulation of phosphoprotein phosphatase activity

0.85	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity
0.54	GO:0046872	metal ion binding
0.51	GO:0072542	protein phosphatase activator activity
0.33	GO:0030246	carbohydrate binding
0.33	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.33	GO:0005515	protein binding

0.74	GO:0000139	Golgi membrane
0.48	GO:0005801	cis-Golgi network
0.35	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.85

EC:2.4.1.135

GO:0015018

tr|Q589R6|Q589R6_CIOIN
Lasp
Search

LASP1

0.84	LIM and SH3 domain protein Lasp

0.43	GO:1902877	positive regulation of embryonic pattern specification
0.43	GO:0014881	regulation of myofibril size
0.43	GO:1904582	positive regulation of intracellular mRNA localization
0.43	GO:0071689	muscle thin filament assembly
0.43	GO:0007279	pole cell formation
0.42	GO:0060282	positive regulation of oocyte development
0.42	GO:1903431	positive regulation of cell maturation
0.42	GO:0007317	regulation of pole plasm oskar mRNA localization
0.42	GO:0007291	sperm individualization
0.41	GO:0045214	sarcomere organization

0.52	GO:0046872	metal ion binding
0.41	GO:0003779	actin binding
0.36	GO:0030296	protein tyrosine kinase activator activity
0.35	GO:0032403	protein complex binding
0.34	GO:0035091	phosphatidylinositol binding
0.33	GO:0016301	kinase activity
0.32	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.32	GO:0140096	catalytic activity, acting on a protein
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding

0.43	GO:0070864	sperm individualization complex
0.41	GO:0031672	A band
0.41	GO:0030018	Z disc
0.41	GO:0005925	focal adhesion
0.34	GO:0055120	striated muscle dense body
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.32

EC:2.7.1

GO:0016773

tr|Q5IFL5|Q5IFL5_CIOIN
POU domain protein
Search

tr|Q5QHQ8|Q5QHQ8_CIOIN
DAZAP2-like protein
Search

DAZAP2

0.84	DAZ-associated protein 2

0.40	GO:0032502	developmental process
0.40	GO:0071391	cellular response to estrogen stimulus
0.39	GO:0045815	positive regulation of gene expression, epigenetic
0.39	GO:2001141	regulation of RNA biosynthetic process
0.38	GO:0022414	reproductive process
0.38	GO:0043044	ATP-dependent chromatin remodeling
0.38	GO:0051254	positive regulation of RNA metabolic process
0.38	GO:0032501	multicellular organismal process
0.38	GO:0010557	positive regulation of macromolecule biosynthetic process
0.38	GO:0031328	positive regulation of cellular biosynthetic process

0.47	GO:0005544	calcium-dependent phospholipid binding
0.45	GO:0005509	calcium ion binding
0.44	GO:0003713	transcription coactivator activity
0.39	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.38	GO:0005515	protein binding
0.38	GO:0001104	RNA polymerase II transcription cofactor activity
0.35	GO:0003676	nucleic acid binding
0.35	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.35	GO:0008270	zinc ion binding
0.34	GO:0030554	adenyl nucleotide binding

0.40	GO:0000790	nuclear chromatin
0.38	GO:0005913	cell-cell adherens junction
0.38	GO:0005886	plasma membrane
0.37	GO:0070062	extracellular exosome
0.36	GO:0016607	nuclear speck
0.36	GO:1904949	ATPase complex
0.35	GO:0000922	spindle pole
0.35	GO:0005815	microtubule organizing center
0.34	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.33

GO:0016887

sp|Q5QQ55|XYLT_CIOIN
Xylosyltransferase
Search

XYLT2

0.72	xylosyltransferase

0.69	GO:0006024	glycosaminoglycan biosynthetic process
0.56	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process
0.56	GO:0015012	heparan sulfate proteoglycan biosynthetic process
0.55	GO:0030202	heparin metabolic process
0.47	GO:0044272	sulfur compound biosynthetic process
0.44	GO:0030204	chondroitin sulfate metabolic process
0.37	GO:0048701	embryonic cranial skeleton morphogenesis

0.86	GO:0030158	protein xylosyltransferase activity
0.77	GO:0008375	acetylglucosaminyltransferase activity

0.41	GO:0000139	Golgi membrane
0.41	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

0.86

EC:2.4.2.26

GO:0030158

tr|Q5SE06|Q5SE06_CIOIN
Elongation of very long chain fatty acids protein
Search

0.55	Elongation of very long chain fatty acids protein 7

0.69	GO:0006633	fatty acid biosynthetic process
0.53	GO:0000038	very long-chain fatty acid metabolic process
0.51	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process
0.49	GO:0033559	unsaturated fatty acid metabolic process
0.44	GO:0035209	pupal development
0.42	GO:0042632	cholesterol homeostasis
0.41	GO:0030148	sphingolipid biosynthetic process
0.41	GO:0006694	steroid biosynthetic process
0.38	GO:0048794	swim bladder development
0.37	GO:0042811	pheromone biosynthetic process

0.81	GO:0102756	very-long-chain 3-ketoacyl-CoA synthase activity
0.81	GO:0102338	3-oxo-lignoceronyl-CoA synthase activity
0.81	GO:0102336	3-oxo-arachidoyl-CoA synthase activity
0.81	GO:0102337	3-oxo-cerotoyl-CoA synthase activity
0.55	GO:0009922	fatty acid elongase activity
0.35	GO:0016491	oxidoreductase activity

0.47	GO:0005783	endoplasmic reticulum
0.47	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.45	GO:0031984	organelle subcompartment
0.35	GO:0030425	dendrite
0.30	GO:0031224	intrinsic component of membrane

0.81

EC:2.3.1.199

GO:0102338

tr|Q5VHU3|Q5VHU3_CIOIN
Ammonium transporter
Search

0.45	Ammonium transporter

0.75	GO:0072488	ammonium transmembrane transport
0.46	GO:0015695	organic cation transport
0.37	GO:0006808	regulation of nitrogen utilization
0.35	GO:0050790	regulation of catalytic activity
0.34	GO:0006298	mismatch repair
0.34	GO:0006351	transcription, DNA-templated
0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression
0.32	GO:0023014	signal transduction by protein phosphorylation

0.75	GO:0008519	ammonium transmembrane transporter activity
0.36	GO:0030234	enzyme regulator activity
0.35	GO:0030983	mismatched DNA binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0000155	phosphorelay sensor kinase activity

0.43	GO:0005887	integral component of plasma membrane
0.31	GO:0005622	intracellular

0.32

EC:2.7.3

GO:0000155

tr|Q5VHU5|Q5VHU5_CIOIN
Ammonium transporter
Search

0.45	Ammonium transporter

0.76	GO:0072488	ammonium transmembrane transport
0.44	GO:0015695	organic cation transport
0.36	GO:0007165	signal transduction
0.34	GO:0006808	regulation of nitrogen utilization
0.34	GO:0006298	mismatch repair
0.33	GO:0050790	regulation of catalytic activity
0.33	GO:0007124	pseudohyphal growth
0.33	GO:0019740	nitrogen utilization
0.33	GO:0006351	transcription, DNA-templated
0.32	GO:1903506	regulation of nucleic acid-templated transcription

0.75	GO:0008519	ammonium transmembrane transporter activity
0.37	GO:0004871	signal transducer activity
0.34	GO:0030983	mismatched DNA binding
0.34	GO:0030234	enzyme regulator activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0004673	protein histidine kinase activity
0.32	GO:0060089	molecular transducer activity

0.41	GO:0005887	integral component of plasma membrane
0.31	GO:0005622	intracellular

0.32

EC:2.7.13.3

GO:0004673

tr|Q5VJS0|Q5VJS0_CIOIN
EKN1
Search

DNAAF4

0.93	Dyslexia susceptibility 1 candidate gene 1

0.83	GO:0003341	cilium movement
0.45	GO:0036158	outer dynein arm assembly
0.45	GO:0033146	regulation of intracellular estrogen receptor signaling pathway
0.45	GO:0036159	inner dynein arm assembly
0.44	GO:0007368	determination of left/right symmetry
0.43	GO:0061136	regulation of proteasomal protein catabolic process

0.45

GO:0030331

estrogen receptor binding

0.41	GO:0005829	cytosol
0.38	GO:0005634	nucleus
0.37	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

tr|Q60GS9|Q60GS9_CIOIN
Tachykinin precurosor
Search

0.85	Tachykinin precurosor

0.85

GO:0007217

tachykinin receptor signaling pathway

tr|Q67EQ6|Q67EQ6_CIOIN
Zinc finger protein 183
Search

RNF113A

0.67	RING finger protein 113A

0.45	GO:0034247	snoRNA splicing
0.43	GO:0045292	mRNA cis splicing, via spliceosome
0.34	GO:0006030	chitin metabolic process

0.52	GO:0046872	metal ion binding
0.34	GO:0008061	chitin binding
0.33	GO:0005515	protein binding

0.43	GO:0005684	U2-type spliceosomal complex
0.33	GO:0005576	extracellular region

tr|Q68A26|Q68A26_CIOIN
Putative uncharacterized protein Ci-Mech3
Search

tr|Q68A28|Q68A28_CIOIN
Peroxiredoxin-like
Search

0.38	Natural killer cell enhancement factor

0.69	GO:0098869	cellular oxidant detoxification
0.69	GO:0045454	cell redox homeostasis
0.53	GO:0055114	oxidation-reduction process
0.39	GO:0000302	response to reactive oxygen species
0.38	GO:0072593	reactive oxygen species metabolic process
0.38	GO:0010035	response to inorganic substance
0.38	GO:0034599	cellular response to oxidative stress
0.38	GO:1901701	cellular response to oxygen-containing compound
0.38	GO:0042267	natural killer cell mediated cytotoxicity
0.37	GO:0030101	natural killer cell activation

0.74	GO:0051920	peroxiredoxin activity
0.48	GO:0004601	peroxidase activity
0.37	GO:0045296	cadherin binding
0.36	GO:0042802	identical protein binding
0.34	GO:0000033	alpha-1,3-mannosyltransferase activity
0.34	GO:0003677	DNA binding
0.33	GO:0004930	G-protein coupled receptor activity

0.37	GO:0043209	myelin sheath
0.36	GO:0005634	nucleus
0.34	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

0.74	EC:1.11.1.15	GO:0051920
0.48	KEGG:R03532	GO:0004601

tr|Q68A30|Q68A30_CIOIN
Putative uncharacterized protein Ci-Mech2
Search

tr|Q68A31|Q68A31_CIOIN
Presenilin-like protein 3
Search

HM13

0.70	Signal peptide peptidase

0.61	GO:0006508	proteolysis
0.47	GO:1903513	endoplasmic reticulum to cytosol transport
0.47	GO:0032527	protein exit from endoplasmic reticulum
0.46	GO:0010033	response to organic substance
0.45	GO:0034976	response to endoplasmic reticulum stress
0.44	GO:1901698	response to nitrogen compound
0.42	GO:0044257	cellular protein catabolic process
0.40	GO:0051604	protein maturation
0.39	GO:0070887	cellular response to chemical stimulus
0.37	GO:0006518	peptide metabolic process

0.70	GO:0070001	aspartic-type peptidase activity
0.65	GO:0004175	endopeptidase activity
0.45	GO:0031625	ubiquitin protein ligase binding
0.44	GO:0042803	protein homodimerization activity

0.51	GO:0071458	integral component of cytoplasmic side of endoplasmic reticulum membrane
0.51	GO:0071556	integral component of lumenal side of endoplasmic reticulum membrane
0.47	GO:0036513	Derlin-1 retrotranslocation complex
0.46	GO:0005791	rough endoplasmic reticulum
0.44	GO:0005765	lysosomal membrane
0.43	GO:0030660	Golgi-associated vesicle membrane
0.36	GO:0009986	cell surface
0.32	GO:0005886	plasma membrane

tr|Q68A32|Q68A32_CIOIN
Translocating chain-associated membrane protein
Search

0.84	Translocating chain-associated membrane protein 1

0.53	GO:0015031	protein transport
0.33	GO:0009435	NAD biosynthetic process

0.33	GO:0003952	NAD+ synthase (glutamine-hydrolyzing) activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.35	GO:1990075	periciliary membrane compartment
0.35	GO:0044292	dendrite terminus
0.34	GO:0005791	rough endoplasmic reticulum
0.30	GO:0016021	integral component of membrane

0.33

EC:6.3.5.1

GO:0003952

tr|Q69HM7|Q69HM7_CIOIN
Uncharacterized protein (Fragment)
Search

tr|Q69HN7|Q69HN7_CIOIN
Uncharacterized protein
Search

tr|Q69HP7|Q69HP7_CIOIN
D-2-hydroxy-acid dehydrogenase-like (Fragment)
Search

0.71	Phosphoglycerate dehydrogenase-like protein

0.53	GO:0055114	oxidation-reduction process
0.36	GO:1903507	negative regulation of nucleic acid-templated transcription

0.68	GO:0051287	NAD binding
0.58	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
0.38	GO:0003714	transcription corepressor activity
0.37	GO:0042803	protein homodimerization activity

0.36	GO:0005829	cytosol
0.35	GO:0005634	nucleus

0.58

EC:1.1.1

GO:0016616

tr|Q69HQ2|Q69HQ2_CIOIN
Adenylate cyclase (Fragment)
Search

0.42	Adenylyl cyclase

0.76	GO:0009190	cyclic nucleotide biosynthetic process
0.75	GO:0046058	cAMP metabolic process
0.63	GO:0009152	purine ribonucleotide biosynthetic process
0.63	GO:0035556	intracellular signal transduction
0.40	GO:0046068	cGMP metabolic process
0.35	GO:0022011	myelination in peripheral nervous system
0.35	GO:1900195	positive regulation of oocyte maturation
0.34	GO:1903830	magnesium ion transmembrane transport

0.76	GO:0004016	adenylate cyclase activity
0.52	GO:1901265	nucleoside phosphate binding
0.51	GO:0036094	small molecule binding
0.40	GO:0004383	guanylate cyclase activity
0.40	GO:0097367	carbohydrate derivative binding
0.40	GO:0008144	drug binding
0.39	GO:0043168	anion binding
0.34	GO:0015095	magnesium ion transmembrane transporter activity

0.54	GO:0005886	plasma membrane
0.45	GO:0005622	intracellular
0.36	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.76

EC:4.6.1.1

GO:0004016

tr|Q69HQ7|Q69HQ7_CIOIN
Calmodulin-like
Search

0.46	Calmodulin-like protein 3 (inferred by orthology to a human protein)

0.41	GO:1990954	establishment of protein localization to meiotic spindle pole body
0.41	GO:0031322	ascospore-type prospore-specific spindle pole body remodeling
0.40	GO:0090307	mitotic spindle assembly
0.38	GO:0009737	response to abscisic acid
0.37	GO:0097306	cellular response to alcohol
0.37	GO:0018105	peptidyl-serine phosphorylation
0.37	GO:0046777	protein autophosphorylation
0.37	GO:0071229	cellular response to acid chemical
0.37	GO:0071396	cellular response to lipid
0.36	GO:0009755	hormone-mediated signaling pathway

0.70	GO:0005509	calcium ion binding
0.38	GO:0009931	calcium-dependent protein serine/threonine kinase activity
0.37	GO:0004683	calmodulin-dependent protein kinase activity
0.37	GO:0005516	calmodulin binding
0.36	GO:0017024	myosin I binding
0.35	GO:0097367	carbohydrate derivative binding
0.35	GO:0017076	purine nucleotide binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0008144	drug binding
0.33	GO:0003924	GTPase activity

0.46	GO:0032588	trans-Golgi network membrane
0.41	GO:0035840	old growing cell tip
0.41	GO:0035841	new growing cell tip
0.41	GO:0035974	meiotic spindle pole body
0.40	GO:0000935	division septum
0.40	GO:0044732	mitotic spindle pole body
0.39	GO:0043332	mating projection tip
0.36	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0005634	nucleus
0.33	GO:0005829	cytosol

0.37

EC:2.7.11.17

GO:0004683

tr|Q69HS7|Q69HS7_CIOIN
Uncharacterized protein (Fragment)
Search

0.68	membrane-associated phosphatidylinositol transfer protein 3-like

0.75	GO:0015914	phospholipid transport
0.45	GO:0048015	phosphatidylinositol-mediated signaling
0.36	GO:0006661	phosphatidylinositol biosynthetic process
0.35	GO:0015031	protein transport
0.34	GO:0007420	brain development
0.34	GO:0007602	phototransduction

0.77	GO:0005548	phospholipid transporter activity
0.58	GO:0030971	receptor tyrosine kinase binding
0.55	GO:0031210	phosphatidylcholine binding
0.55	GO:0070300	phosphatidic acid binding
0.53	GO:0046872	metal ion binding
0.49	GO:0035091	phosphatidylinositol binding

0.51	GO:0036464	cytoplasmic ribonucleoprotein granule
0.49	GO:0005815	microtubule organizing center
0.47	GO:0005829	cytosol
0.41	GO:0044297	cell body
0.38	GO:0097610	cell surface furrow
0.38	GO:0030496	midbody
0.38	GO:0005811	lipid droplet
0.38	GO:0032155	cell division site part
0.38	GO:0032580	Golgi cisterna membrane
0.36	GO:0005789	endoplasmic reticulum membrane

tr|Q6A1F0|Q6A1F0_CIOIN
Alpha3-fucosyltransferase
Search

0.84	galactoside 3(4)-L-fucosyltransferase

0.81	GO:0036065	fucosylation
0.74	GO:0006486	protein glycosylation
0.43	GO:0002522	leukocyte migration involved in immune response
0.43	GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
0.41	GO:0006672	ceramide metabolic process
0.33	GO:0042355	L-fucose catabolic process
0.33	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.33	GO:0030001	metal ion transport
0.32	GO:0006468	protein phosphorylation

0.81	GO:0008417	fucosyltransferase activity
0.33	GO:0005507	copper ion binding
0.33	GO:0019829	cation-transporting ATPase activity
0.32	GO:0004672	protein kinase activity
0.32	GO:1901265	nucleoside phosphate binding
0.32	GO:0036094	small molecule binding
0.32	GO:0008144	drug binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0043168	anion binding

0.80	GO:0032580	Golgi cisterna membrane
0.30	GO:0031224	intrinsic component of membrane

0.81

GO:0008417

tr|Q6IMM2|Q6IMM2_CIOIN
RBJ protein
Search

DNAJC27

0.97	Rab and DnaJ domain-containing

0.58	GO:0071701	regulation of MAPK export from nucleus
0.54	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.33	GO:0042981	regulation of apoptotic process

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding
0.33	GO:0005509	calcium ion binding

0.45	GO:0005634	nucleus
0.44	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

tr|Q6L5M4|Q6L5M4_CIOIN
Interleukin 17-3
Search

IL-17-3

0.93	Interleukin 17-3

0.76	GO:0010469	regulation of receptor activity
0.61	GO:0006954	inflammatory response
0.41	GO:0071222	cellular response to lipopolysaccharide

0.81

GO:0005125

cytokine activity

0.66	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

tr|Q6L5M5|Q6L5M5_CIOIN
Interleukin 17-2
Search

IL-17-2

0.95	interleukin 17-2 precursor

0.76

GO:0010469

regulation of receptor activity

0.81

GO:0005125

cytokine activity

0.66

GO:0005576

extracellular region

tr|Q6L5M6|Q6L5M6_CIOIN
Interleukin 17-1
Search

IL-17-1

0.92	interleukin 17-1 precursor

0.76	GO:0006954	inflammatory response
0.76	GO:0010469	regulation of receptor activity
0.50	GO:0042109	lymphotoxin A biosynthetic process
0.50	GO:0045423	regulation of granulocyte macrophage colony-stimulating factor biosynthetic process
0.49	GO:0045414	regulation of interleukin-8 biosynthetic process
0.49	GO:1900017	positive regulation of cytokine production involved in inflammatory response
0.48	GO:0045076	regulation of interleukin-2 biosynthetic process
0.48	GO:2000778	positive regulation of interleukin-6 secretion
0.48	GO:0045408	regulation of interleukin-6 biosynthetic process
0.47	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway

0.81	GO:0005125	cytokine activity
0.47	GO:0019955	cytokine binding
0.45	GO:0005126	cytokine receptor binding
0.44	GO:0042803	protein homodimerization activity

0.66	GO:0005576	extracellular region
0.30	GO:0016020	membrane

tr|Q6XLI4|Q6XLI4_CIOIN
Swan
Search

0.58	GO:0003723	RNA binding
0.32	GO:0005515	protein binding

0.30

GO:0044425

membrane part

tr|Q6XV77|Q6XV77_CIOIN
RhAG-like protein
Search

0.79	Ammonium transporter Rh type B-B

0.77	GO:0072488	ammonium transmembrane transport
0.42	GO:0019755	one-carbon compound transport
0.41	GO:0015695	organic cation transport
0.39	GO:0097272	ammonia homeostasis
0.37	GO:0042886	amide transport
0.35	GO:0015669	gas transport
0.35	GO:0006873	cellular ion homeostasis
0.35	GO:0070634	transepithelial ammonium transport
0.35	GO:0060586	multicellular organismal iron ion homeostasis
0.34	GO:0048821	erythrocyte development

0.77	GO:0008519	ammonium transmembrane transporter activity
0.37	GO:0030506	ankyrin binding
0.36	GO:0022842	narrow pore channel activity
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.39	GO:0044459	plasma membrane part
0.37	GO:0030659	cytoplasmic vesicle membrane
0.35	GO:0014731	spectrin-associated cytoskeleton
0.34	GO:0031225	anchored component of membrane
0.30	GO:0016021	integral component of membrane

tr|Q6XZ09|Q6XZ09_CIOIN
Rh type B glycoprotein
Search

0.80	Ammonium transporter Rh type B-A

0.77	GO:0072488	ammonium transmembrane transport
0.51	GO:0019755	one-carbon compound transport
0.47	GO:0060586	multicellular organismal iron ion homeostasis
0.46	GO:0006873	cellular ion homeostasis
0.46	GO:0048821	erythrocyte development
0.46	GO:0015669	gas transport
0.45	GO:0015695	organic cation transport
0.43	GO:0015893	drug transport
0.41	GO:0015672	monovalent inorganic cation transport
0.38	GO:0042886	amide transport

0.77	GO:0008519	ammonium transmembrane transporter activity
0.52	GO:0030506	ankyrin binding
0.49	GO:0022842	narrow pore channel activity
0.35	GO:0042802	identical protein binding
0.35	GO:0035379	carbon dioxide transmembrane transporter activity

0.42	GO:0005887	integral component of plasma membrane
0.39	GO:0016323	basolateral plasma membrane
0.37	GO:0045177	apical part of cell
0.36	GO:0030659	cytoplasmic vesicle membrane
0.35	GO:0016327	apicolateral plasma membrane
0.34	GO:0005576	extracellular region

tr|Q6XZ10|Q6XZ10_CIOIN
Rh type C glycoprotein
Search

0.82	Ammonium transporter Rh type B-A

0.77	GO:0072488	ammonium transmembrane transport
0.51	GO:0019755	one-carbon compound transport
0.47	GO:0060586	multicellular organismal iron ion homeostasis
0.46	GO:0006873	cellular ion homeostasis
0.46	GO:0015695	organic cation transport
0.46	GO:0048821	erythrocyte development
0.45	GO:0015669	gas transport
0.43	GO:0015893	drug transport
0.41	GO:0015672	monovalent inorganic cation transport
0.38	GO:0042886	amide transport

0.77	GO:0008519	ammonium transmembrane transporter activity
0.52	GO:0030506	ankyrin binding
0.49	GO:0022842	narrow pore channel activity
0.35	GO:0042802	identical protein binding
0.35	GO:0035379	carbon dioxide transmembrane transporter activity

0.43	GO:0005887	integral component of plasma membrane
0.39	GO:0016323	basolateral plasma membrane
0.36	GO:0030659	cytoplasmic vesicle membrane
0.36	GO:0016324	apical plasma membrane
0.35	GO:0016327	apicolateral plasma membrane
0.34	GO:0005576	extracellular region

tr|Q70VZ3|Q70VZ3_CIOIN
FoxE
Search

0.47	Transcription factor protein

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0009887	animal organ morphogenesis
0.51	GO:1904888	cranial skeletal system development
0.50	GO:0009888	tissue development
0.49	GO:0048568	embryonic organ development
0.49	GO:0060022	hard palate development
0.49	GO:0060465	pharynx development
0.48	GO:0060023	soft palate development

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity

0.61	GO:0005634	nucleus
0.39	GO:0005667	transcription factor complex

tr|Q70W02|Q70W02_CIOIN
SoxE protein (Fragment)
Search

0.86	SoxE protein (Fragment)

0.68	GO:0006357	regulation of transcription by RNA polymerase II
0.54	GO:0072289	metanephric nephron tubule formation
0.54	GO:0060221	retinal rod cell differentiation
0.54	GO:0072034	renal vesicle induction
0.54	GO:0072197	ureter morphogenesis
0.53	GO:0060018	astrocyte fate commitment
0.53	GO:0048709	oligodendrocyte differentiation
0.53	GO:0046533	negative regulation of photoreceptor cell differentiation
0.53	GO:0060008	Sertoli cell differentiation
0.52	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis

0.71	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.55	GO:0003677	DNA binding
0.47	GO:0001067	regulatory region nucleic acid binding
0.46	GO:0046982	protein heterodimerization activity
0.46	GO:0008134	transcription factor binding
0.39	GO:0003682	chromatin binding
0.35	GO:0097157	pre-mRNA intronic binding
0.34	GO:0034236	protein kinase A catalytic subunit binding
0.34	GO:0008013	beta-catenin binding
0.34	GO:0004672	protein kinase activity

0.61	GO:0005634	nucleus
0.47	GO:0005667	transcription factor complex
0.40	GO:0044446	intracellular organelle part
0.38	GO:0005737	cytoplasm
0.33	GO:0070013	intracellular organelle lumen
0.30	GO:0016020	membrane

tr|Q7YEU2|Q7YEU2_CIOIN
ATP synthase subunit 8
Search

0.44	ATP synthase subunit 8

0.61	GO:0005739	mitochondrion
0.30	GO:0044425	membrane part

tr|Q7YT70|Q7YT70_CIOIN
TC10 protein
Search

RHO1

0.41	GTP-binding protein rhoA

0.77	GO:0007264	small GTPase mediated signal transduction
0.45	GO:1903395	regulation of secondary cell septum biogenesis
0.44	GO:0090334	regulation of cell wall (1->3)-beta-D-glucan biosynthetic process
0.44	GO:0090037	positive regulation of protein kinase C signaling
0.44	GO:0060178	regulation of exocyst localization
0.44	GO:0032186	cellular bud neck septin ring organization
0.44	GO:0032889	regulation of vacuole fusion, non-autophagic
0.43	GO:0060237	regulation of fungal-type cell wall organization
0.43	GO:0007117	budding cell bud growth
0.43	GO:0045807	positive regulation of endocytosis

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.34	GO:0019901	protein kinase binding
0.34	GO:0004664	prephenate dehydratase activity
0.33	GO:0022857	transmembrane transporter activity
0.33	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.32	GO:0008270	zinc ion binding
0.32	GO:0003677	DNA binding

0.45	GO:0005622	intracellular
0.43	GO:0000148	1,3-beta-D-glucan synthase complex
0.43	GO:0005934	cellular bud tip
0.42	GO:0043332	mating projection tip
0.42	GO:0005935	cellular bud neck
0.39	GO:0012505	endomembrane system
0.37	GO:0043227	membrane-bounded organelle
0.35	GO:0001411	hyphal tip
0.34	GO:0030175	filopodium
0.30	GO:0016021	integral component of membrane

0.34

EC:4.2.1.51

GO:0004664

tr|Q7YT71|Q7YT71_CIOIN
Rif protein
Search

RHO1

0.27	GTP-binding protein rhoA

0.77	GO:0007264	small GTPase mediated signal transduction
0.44	GO:1903395	regulation of secondary cell septum biogenesis
0.44	GO:0090334	regulation of cell wall (1->3)-beta-D-glucan biosynthetic process
0.44	GO:0090037	positive regulation of protein kinase C signaling
0.44	GO:0060178	regulation of exocyst localization
0.44	GO:0032186	cellular bud neck septin ring organization
0.43	GO:0032889	regulation of vacuole fusion, non-autophagic
0.43	GO:0060237	regulation of fungal-type cell wall organization
0.43	GO:0007117	budding cell bud growth
0.42	GO:0045807	positive regulation of endocytosis

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.34	GO:0019901	protein kinase binding
0.33	GO:0004664	prephenate dehydratase activity
0.33	GO:0022857	transmembrane transporter activity
0.33	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.32	GO:0008270	zinc ion binding
0.32	GO:0003677	DNA binding

0.45	GO:0005622	intracellular
0.43	GO:0000148	1,3-beta-D-glucan synthase complex
0.42	GO:0005935	cellular bud neck
0.42	GO:0005934	cellular bud tip
0.42	GO:0043332	mating projection tip
0.39	GO:0012505	endomembrane system
0.36	GO:0043227	membrane-bounded organelle
0.35	GO:0001411	hyphal tip
0.30	GO:0016021	integral component of membrane

0.33

EC:4.2.1.51

GO:0004664

tr|Q7YT72|Q7YT72_CIOIN
Rcl2 protein
Search

0.52	p-loop containing nucleoside triphosphate hydrolase

0.77	GO:0007264	small GTPase mediated signal transduction
0.62	GO:0000917	division septum assembly
0.58	GO:0032955	regulation of division septum assembly
0.56	GO:0032956	regulation of actin cytoskeleton organization
0.51	GO:0008360	regulation of cell shape
0.51	GO:0034613	cellular protein localization
0.42	GO:0030011	maintenance of cell polarity
0.40	GO:1902905	positive regulation of supramolecular fiber organization
0.40	GO:0051495	positive regulation of cytoskeleton organization
0.40	GO:0044089	positive regulation of cellular component biogenesis

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0004767	sphingomyelin phosphodiesterase activity
0.34	GO:0019901	protein kinase binding

0.61	GO:0000935	division septum
0.55	GO:0005938	cell cortex
0.41	GO:0000131	incipient cellular bud site
0.41	GO:0005935	cellular bud neck
0.39	GO:0000329	fungal-type vacuole membrane
0.37	GO:0005886	plasma membrane
0.37	GO:0012505	endomembrane system

0.34	EC:3.1.4.12	GO:0004767
0.34	KEGG:R02541	GO:0004767

tr|Q7YT73|Q7YT73_CIOIN
Rcl1 protein
Search

RHOG

0.85	Rho GTPase

0.77	GO:0007264	small GTPase mediated signal transduction
0.46	GO:0048522	positive regulation of cellular process
0.45	GO:0044087	regulation of cellular component biogenesis
0.45	GO:0060341	regulation of cellular localization
0.44	GO:0051128	regulation of cellular component organization
0.44	GO:0016477	cell migration
0.44	GO:0090630	activation of GTPase activity
0.44	GO:0007010	cytoskeleton organization
0.44	GO:0032970	regulation of actin filament-based process
0.43	GO:0006935	chemotaxis

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.37	GO:0019901	protein kinase binding
0.36	GO:0019904	protein domain specific binding

0.45	GO:0005622	intracellular
0.44	GO:0005933	cellular bud
0.43	GO:0030427	site of polarized growth
0.42	GO:0000935	division septum
0.38	GO:0005937	mating projection
0.38	GO:0071944	cell periphery
0.37	GO:0120038	plasma membrane bounded cell projection part
0.37	GO:0031252	cell leading edge
0.36	GO:0098805	whole membrane
0.36	GO:0012505	endomembrane system

tr|Q7YT74|Q7YT74_CIOIN
Rac5 protein
Search

RAC1

0.59	Probable GTP-binding protein rac1

0.77

GO:0007264

small GTPase mediated signal transduction

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032553	ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.45	GO:0005622	intracellular
0.30	GO:0031224	intrinsic component of membrane

tr|Q7YT75|Q7YT75_CIOIN
Rac4 protein
Search

RAC2

0.74	Small GTP-binding protein domain

0.77	GO:0007264	small GTPase mediated signal transduction
0.53	GO:0071593	lymphocyte aggregation
0.53	GO:0060753	regulation of mast cell chemotaxis
0.53	GO:1902624	positive regulation of neutrophil migration
0.52	GO:0060263	regulation of respiratory burst
0.52	GO:0010592	positive regulation of lamellipodium assembly
0.52	GO:0043304	regulation of mast cell degranulation
0.52	GO:0071624	positive regulation of granulocyte chemotaxis
0.52	GO:0090022	regulation of neutrophil chemotaxis
0.50	GO:1903955	positive regulation of protein targeting to mitochondrion

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.48	GO:0019887	protein kinase regulator activity
0.36	GO:0004994	somatostatin receptor activity
0.34	GO:0004754	saccharopine dehydrogenase (NAD+, L-lysine-forming) activity
0.33	GO:0005515	protein binding

0.49	GO:0005884	actin filament
0.49	GO:0030027	lamellipodium
0.47	GO:0005635	nuclear envelope
0.44	GO:0005829	cytosol
0.35	GO:0005925	focal adhesion
0.35	GO:0070062	extracellular exosome
0.35	GO:0005581	collagen trimer
0.34	GO:0030670	phagocytic vesicle membrane
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.34	EC:1.5.1.7	GO:0004754
0.34	KEGG:R00715	GO:0004754

tr|Q7YT79|Q7YT79_CIOIN
Rac1 protein
Search

0.80	Rac small GTPase

0.77	GO:0007264	small GTPase mediated signal transduction
0.51	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading
0.50	GO:0021894	cerebral cortex GABAergic interneuron development
0.50	GO:0051932	synaptic transmission, GABAergic
0.50	GO:0014041	regulation of neuron maturation
0.49	GO:0048873	homeostasis of number of cells within a tissue
0.48	GO:0033630	positive regulation of cell adhesion mediated by integrin
0.47	GO:0120036	plasma membrane bounded cell projection organization
0.47	GO:0050885	neuromuscular process controlling balance
0.46	GO:0030036	actin cytoskeleton organization

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.47	GO:0048306	calcium-dependent protein binding
0.43	GO:0031996	thioesterase binding
0.42	GO:0051022	Rho GDP-dissociation inhibitor binding
0.42	GO:0019901	protein kinase binding
0.38	GO:0030742	GTP-dependent protein binding
0.37	GO:0051117	ATPase binding
0.37	GO:0042826	histone deacetylase binding
0.37	GO:0017137	Rab GTPase binding

0.49	GO:0005884	actin filament
0.48	GO:0036477	somatodendritic compartment
0.48	GO:0043005	neuron projection
0.47	GO:0120038	plasma membrane bounded cell projection part
0.45	GO:0044297	cell body
0.45	GO:0030427	site of polarized growth
0.45	GO:0048471	perinuclear region of cytoplasm
0.44	GO:0012505	endomembrane system
0.43	GO:0030027	lamellipodium
0.42	GO:0031256	leading edge membrane

tr|Q7YT82|Q7YT82_CIOIN
RhoA protein
Search

0.56	Guanine nucleotide-binding protein Rho

0.77	GO:0007264	small GTPase mediated signal transduction
0.52	GO:1902766	skeletal muscle satellite cell migration
0.52	GO:0042060	wound healing
0.51	GO:0002009	morphogenesis of an epithelium
0.49	GO:0045216	cell-cell junction organization
0.49	GO:0061640	cytoskeleton-dependent cytokinesis
0.47	GO:0032464	positive regulation of protein homooligomerization
0.46	GO:1903047	mitotic cell cycle process
0.45	GO:0043085	positive regulation of catalytic activity
0.45	GO:0035026	leading edge cell differentiation

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.42	GO:0019900	kinase binding
0.36	GO:0032794	GTPase activating protein binding
0.34	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.33	GO:0004725	protein tyrosine phosphatase activity
0.33	GO:0003779	actin binding
0.33	GO:0004871	signal transducer activity

0.46	GO:0097610	cell surface furrow
0.46	GO:0120025	plasma membrane bounded cell projection
0.45	GO:0032421	stereocilium bundle
0.45	GO:0032155	cell division site part
0.45	GO:0005622	intracellular
0.43	GO:0044291	cell-cell contact zone
0.42	GO:0016324	apical plasma membrane
0.38	GO:0044422	organelle part
0.37	GO:0043227	membrane-bounded organelle
0.34	GO:0043230	extracellular organelle

0.34

EC:3.1.3

GO:0008138

tr|Q7YXB3|Q7YXB3_CIOIN
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase
Search

0.77	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase

0.74	GO:0006486	protein glycosylation
0.48	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process
0.48	GO:0030204	chondroitin sulfate metabolic process
0.39	GO:0005975	carbohydrate metabolic process
0.38	GO:0060465	pharynx development
0.38	GO:0040025	vulval development
0.38	GO:0018991	oviposition
0.37	GO:0007286	spermatid development
0.36	GO:0002009	morphogenesis of an epithelium
0.36	GO:0009792	embryo development ending in birth or egg hatching

0.85	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity
0.54	GO:0046872	metal ion binding
0.38	GO:0046987	N-acetyllactosamine beta-1,3-glucuronosyltransferase activity
0.38	GO:0046988	asioloorosomucoid beta-1,3-glucuronosyltransferase activity
0.38	GO:0046989	galactosyl beta-1,3 N-acetylgalactosamine beta-1,3-glucuronosyltransferase activity
0.33	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.33	GO:0004725	protein tyrosine phosphatase activity

0.74	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

0.85

EC:2.4.1.135

GO:0015018

tr|Q7YZS7|Q7YZS7_CIOIN
Putative uncharacterized protein fut13
Search

POFUT2

0.93	GDP-fucose protein O-fucosyltransferase 2

0.79	GO:0006004	fucose metabolic process
0.56	GO:0036066	protein O-linked fucosylation
0.49	GO:0001707	mesoderm formation
0.49	GO:0010717	regulation of epithelial to mesenchymal transition
0.47	GO:0051046	regulation of secretion
0.39	GO:0060255	regulation of macromolecule metabolic process
0.34	GO:0006869	lipid transport
0.33	GO:0007017	microtubule-based process
0.33	GO:0007010	cytoskeleton organization
0.32	GO:0055085	transmembrane transport

0.65	GO:0016757	transferase activity, transferring glycosyl groups
0.42	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0005200	structural constituent of cytoskeleton
0.33	GO:0017111	nucleoside-triphosphatase activity
0.33	GO:0015399	primary active transmembrane transporter activity
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0019001	guanyl nucleotide binding
0.32	GO:0030554	adenyl nucleotide binding

0.45	GO:0005794	Golgi apparatus
0.36	GO:0005783	endoplasmic reticulum
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0031984	organelle subcompartment
0.33	GO:0005874	microtubule
0.30	GO:0016021	integral component of membrane

0.65

GO:0016757

tr|Q869J2|Q869J2_CIOIN
Gonadotropin-releasing hormone receptor
Search

0.75	Gonadotropin-releasing hormone receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.48	GO:1901652	response to peptide
0.46	GO:0032870	cellular response to hormone stimulus

0.72	GO:0004930	G-protein coupled receptor activity
0.47	GO:0042277	peptide binding
0.43	GO:0016500	protein-hormone receptor activity
0.40	GO:0001653	peptide receptor activity

0.43

GO:0005887

integral component of plasma membrane

tr|Q86NA9|Q86NA9_CIOIN
Putative alpha3-fucosyltransferase
Search

0.72	Alpha3-fucosyltransferase

0.81	GO:0036065	fucosylation
0.74	GO:0006486	protein glycosylation

0.81

GO:0008417

fucosyltransferase activity

0.80	GO:0032580	Golgi cisterna membrane
0.35	GO:0009986	cell surface
0.33	GO:0071944	cell periphery
0.30	GO:0031224	intrinsic component of membrane

0.81

GO:0008417

tr|Q86SC5|Q86SC5_CIOIN
Thymosin beta homologue
Search

0.10	Thymosin beta homologue

0.74	GO:0007015	actin filament organization
0.37	GO:0048856	anatomical structure development
0.37	GO:0032501	multicellular organismal process
0.36	GO:0019953	sexual reproduction
0.36	GO:0003006	developmental process involved in reproduction
0.35	GO:0030154	cell differentiation

0.84	GO:0003785	actin monomer binding
0.35	GO:0030554	adenyl nucleotide binding
0.35	GO:0032553	ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.42	GO:0005856	cytoskeleton
0.37	GO:0005737	cytoplasm

tr|Q86SC6|Q86SC6_CIOIN
Notochord specific gene 8 protein
Search

0.93	Notochord specific gene 8 protein

0.66	GO:0055074	calcium ion homeostasis
0.63	GO:0035725	sodium ion transmembrane transport

0.70	GO:0005509	calcium ion binding
0.70	GO:0005432	calcium:sodium antiporter activity

tr|Q86SD3|Q86SD3_CIOIN
Beta-transducin repeat-containing homologue protein
Search

BTRC

0.93	Beta-transducin repeat containing

0.53	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
0.52	GO:0042753	positive regulation of circadian rhythm
0.51	GO:0031648	protein destabilization
0.50	GO:0033598	mammary gland epithelial cell proliferation
0.50	GO:0060444	branching involved in mammary gland duct morphogenesis
0.50	GO:0000209	protein polyubiquitination
0.50	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling
0.49	GO:0060828	regulation of canonical Wnt signaling pathway
0.48	GO:0061136	regulation of proteasomal protein catabolic process
0.48	GO:0045862	positive regulation of proteolysis

0.68	GO:0046983	protein dimerization activity
0.51	GO:0045309	protein phosphorylated amino acid binding
0.51	GO:0008013	beta-catenin binding
0.48	GO:0061630	ubiquitin protein ligase activity
0.33	GO:0004674	protein serine/threonine kinase activity
0.33	GO:0016874	ligase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.50	GO:0019005	SCF ubiquitin ligase complex
0.42	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm
0.33	GO:0070013	intracellular organelle lumen
0.32	GO:0044446	intracellular organelle part

0.33

GO:0004674

tr|Q8HIM8|Q8HIM8_CIOIN
NADH dehydrogenase subunit 5
Search

ND5

0.44	NADH-ubiquinone oxidoreductase chain 5

0.67

GO:0042773

ATP synthesis coupled electron transport

0.67

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.61	GO:0005739	mitochondrion
0.60	GO:0070469	respiratory chain
0.60	GO:0019866	organelle inner membrane
0.35	GO:0030964	NADH dehydrogenase complex
0.34	GO:1990204	oxidoreductase complex
0.34	GO:0098796	membrane protein complex
0.30	GO:0031224	intrinsic component of membrane

0.67

GO:0008137

tr|Q8HIM9|Q8HIM9_CIOIN
Cytochrome c oxidase subunit 1
Search

COX1

0.25	Cytochrome c oxidase subunit 1

0.64	GO:0009060	aerobic respiration
0.63	GO:0006119	oxidative phosphorylation
0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0022900	electron transport chain

0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0020037	heme binding
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.63	GO:0005506	iron ion binding
0.62	GO:0009055	electron transfer activity

0.62	GO:0070469	respiratory chain
0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.58	GO:0070069	cytochrome complex
0.52	GO:0098796	membrane protein complex
0.35	GO:0098798	mitochondrial protein complex
0.30	GO:0016021	integral component of membrane

0.65

EC:1.9.3

GO:0016676

tr|Q8HIN0|Q8HIN0_CIOIN
NADH-ubiquinone oxidoreductase chain 4
Search

NAD4

0.39	NADH-ubiquinone oxidoreductase chain 4

0.65

GO:0042773

ATP synthesis coupled electron transport

0.65

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.56	GO:0005739	mitochondrion
0.32	GO:0070469	respiratory chain
0.32	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

0.65

GO:0008137

tr|Q8HIN1|Q8HIN1_CIOIN
NADH-ubiquinone oxidoreductase chain 3
Search

NAD3

0.40	NADH-ubiquinone oxidoreductase chain 3

0.53	GO:0055114	oxidation-reduction process
0.34	GO:0006119	oxidative phosphorylation

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.61	GO:0005739	mitochondrion
0.56	GO:0070469	respiratory chain
0.56	GO:0031967	organelle envelope
0.55	GO:0031090	organelle membrane
0.44	GO:0030964	NADH dehydrogenase complex
0.41	GO:1990204	oxidoreductase complex
0.39	GO:0098796	membrane protein complex
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0008137

tr|Q8HIN2|Q8HIN2_CIOIN
NADH-ubiquinone oxidoreductase chain 1
Search

NAD1

0.42	NADH-ubiquinone oxidoreductase chain 1

0.53	GO:0055114	oxidation-reduction process
0.33	GO:0006091	generation of precursor metabolites and energy

0.69

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.35	GO:0045271	respiratory chain complex I
0.34	GO:0098798	mitochondrial protein complex
0.34	GO:1990204	oxidoreductase complex
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0008137

tr|Q8HIN3|Q8HIN3_CIOIN
Cytochrome c oxidase subunit 3
Search

COX3

0.42	Cytochrome c oxidase subunit III

0.75	GO:0019646	aerobic electron transport chain
0.62	GO:1902600	hydrogen ion transmembrane transport
0.34	GO:0008535	respiratory chain complex IV assembly

0.64	GO:0015002	heme-copper terminal oxidase activity
0.64	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.61	GO:0009055	electron transfer activity

0.59	GO:0005739	mitochondrion
0.35	GO:0005886	plasma membrane
0.33	GO:0045277	respiratory chain complex IV
0.33	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.64

EC:1.9.3

GO:0016676

tr|Q8HIN4|Q8HIN4_CIOIN
NADH dehydrogenase subunit 4L
Search

0.44	NADH dehydrogenase subunit 4L

0.61	GO:0005739	mitochondrion
0.30	GO:0044425	membrane part

tr|Q8HIN5|Q8HIN5_CIOIN
Cytochrome b
Search

CYTB

0.41	Cytochrome b

0.70

GO:0006122

mitochondrial electron transport, ubiquinol to cytochrome c

0.70	GO:0016681	oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor
0.62	GO:0009055	electron transfer activity
0.53	GO:0046872	metal ion binding

0.69	GO:0045275	respiratory chain complex III
0.61	GO:0031966	mitochondrial membrane
0.61	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.70

EC:1.10.2

GO:0016681

tr|Q8HIN6|Q8HIN6_CIOIN
Cytochrome c oxidase subunit 2
Search

COX2

0.40	Cytochrome c oxidase subunit II

0.63	GO:1902600	hydrogen ion transmembrane transport
0.61	GO:0022900	electron transport chain
0.34	GO:0006119	oxidative phosphorylation
0.34	GO:0045333	cellular respiration

0.72	GO:0005507	copper ion binding
0.65	GO:0015002	heme-copper terminal oxidase activity
0.65	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.62	GO:0009055	electron transfer activity

0.62	GO:0070469	respiratory chain
0.61	GO:0031966	mitochondrial membrane
0.61	GO:0019866	organelle inner membrane
0.35	GO:0098798	mitochondrial protein complex
0.35	GO:0070069	cytochrome complex
0.34	GO:0098796	membrane protein complex
0.30	GO:0016021	integral component of membrane

0.65

EC:1.9.3

GO:0016676

tr|Q8HIN7|Q8HIN7_CIOIN
NADH dehydrogenase subunit 2
Search

0.40	NADH dehydrogenase subunit 2

0.61	GO:0005739	mitochondrion
0.30	GO:0044425	membrane part

tr|Q8HIN8|Q8HIN8_CIOIN
ATP synthase subunit a
Search

ATP6

0.42	ATP synthase subunit a

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.36	GO:0099132	ATP hydrolysis coupled cation transmembrane transport

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.36	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
0.36	GO:0019829	cation-transporting ATPase activity

0.72	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)
0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.34	GO:0005886	plasma membrane
0.33	GO:0098798	mitochondrial protein complex
0.30	GO:0016021	integral component of membrane

tr|Q8HIN9|Q8HIN9_CIOIN
NADH-ubiquinone oxidoreductase chain 6
Search

0.39	NADH-ubiquinone oxidoreductase chain 6

0.48

GO:0055114

oxidation-reduction process

0.60

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.61	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.60

GO:0008137

tr|Q8I6J7|Q8I6J7_CIOIN
Fibroblast growth factor 3/7/10/22
Search

0.93	fibroblast growth factor 3/7/10/22

0.76	GO:0010469	regulation of receptor activity
0.56	GO:0008543	fibroblast growth factor receptor signaling pathway
0.45	GO:0055026	negative regulation of cardiac muscle tissue development
0.44	GO:0048522	positive regulation of cellular process
0.42	GO:0051302	regulation of cell division
0.42	GO:0042127	regulation of cell proliferation
0.40	GO:0030154	cell differentiation
0.40	GO:0007275	multicellular organism development

0.78	GO:0008083	growth factor activity
0.57	GO:0005104	fibroblast growth factor receptor binding

0.48

GO:0005576

extracellular region

sp|Q8I7D5|RS23_CIOIN
40S ribosomal protein S23
Search

RPS23

0.75	Ribosomal protein S23

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.51	GO:0034063	stress granule assembly
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0046072	dTDP metabolic process
0.34	GO:0009197	pyrimidine deoxyribonucleoside diphosphate biosynthetic process
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.33	GO:0019083	viral transcription

0.64	GO:0003735	structural constituent of ribosome
0.34	GO:0045182	translation regulator activity
0.34	GO:0005515	protein binding
0.34	GO:0004798	thymidylate kinase activity
0.33	GO:0003723	RNA binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.69	GO:0015935	small ribosomal subunit
0.52	GO:0022626	cytosolic ribosome
0.52	GO:0042788	polysomal ribosome
0.45	GO:0005783	endoplasmic reticulum
0.34	GO:0098562	cytoplasmic side of membrane
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0005654	nucleoplasm
0.33	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:2.7.4.9

GO:0004798

sp|Q8I7D6|RS13_CIOIN
40S ribosomal protein S13
Search

RPS13

0.69	Ribosomal protein S13

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.47	GO:0033119	negative regulation of RNA splicing
0.36	GO:0048015	phosphatidylinositol-mediated signaling
0.35	GO:0046854	phosphatidylinositol phosphorylation
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription

0.64	GO:0003735	structural constituent of ribosome
0.47	GO:0070181	small ribosomal subunit rRNA binding
0.45	GO:0048027	mRNA 5'-UTR binding
0.35	GO:1990932	5.8S rRNA binding
0.34	GO:0035091	phosphatidylinositol binding
0.34	GO:0005515	protein binding
0.34	GO:0016301	kinase activity
0.33	GO:0008408	3'-5' exonuclease activity

0.61	GO:0005840	ribosome
0.47	GO:0005730	nucleolus
0.46	GO:0044445	cytosolic part
0.36	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.33	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

sp|Q8I7D9|SC61G_CIOIN
Protein transport protein Sec61 subunit gamma
Search

SEC61G

0.85	Mitochondrial import inner membrane translocase subunit TIM8

0.71	GO:0006605	protein targeting
0.70	GO:0071806	protein transmembrane transport
0.40	GO:0072599	establishment of protein localization to endoplasmic reticulum
0.36	GO:0010507	negative regulation of autophagy
0.36	GO:0001555	oocyte growth
0.36	GO:0030728	ovulation
0.34	GO:0036498	IRE1-mediated unfolded protein response
0.34	GO:0016310	phosphorylation
0.34	GO:0006695	cholesterol biosynthetic process
0.34	GO:0022406	membrane docking

0.75	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
0.35	GO:0016301	kinase activity
0.33	GO:0005543	phospholipid binding
0.33	GO:0016776	phosphotransferase activity, phosphate group as acceptor
0.33	GO:0005515	protein binding

0.45	GO:0005622	intracellular
0.40	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.37	GO:0044422	organelle part
0.36	GO:0043227	membrane-bounded organelle
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:2.7.4

GO:0016776

tr|Q8I7E2|Q8I7E2_CIOIN
ER lumen protein-retaining receptor
Search

KDELR2

0.66	ER lumen protein-retaining receptor

0.84	GO:0006621	protein retention in ER lumen
0.65	GO:0015031	protein transport
0.38	GO:0016192	vesicle-mediated transport
0.35	GO:0036498	IRE1-mediated unfolded protein response
0.33	GO:0046907	intracellular transport
0.33	GO:0006629	lipid metabolic process

0.84	GO:0046923	ER retention sequence binding
0.33	GO:0003676	nucleic acid binding
0.32	GO:0016787	hydrolase activity

0.72	GO:0005789	endoplasmic reticulum membrane
0.37	GO:0005801	cis-Golgi network
0.36	GO:0070062	extracellular exosome
0.35	GO:0030133	transport vesicle
0.35	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016787

tr|Q8I7E3|Q8I7E3_CIOIN
Actin-related protein 2/3 complex subunit 4
Search

ARPC4

0.71	Actin-related protein 2/3 complex subunit 4

0.81	GO:0030041	actin filament polymerization
0.79	GO:0034314	Arp2/3 complex-mediated actin nucleation
0.35	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.35	GO:0048013	ephrin receptor signaling pathway
0.33	GO:0061024	membrane organization

0.68	GO:0003779	actin binding
0.50	GO:0030674	protein binding, bridging
0.48	GO:0005200	structural constituent of cytoskeleton
0.48	GO:0032403	protein complex binding
0.46	GO:0019899	enzyme binding

0.78	GO:0005885	Arp2/3 protein complex
0.46	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.35	GO:0042995	cell projection

tr|Q8IAC7|Q8IAC7_CIOIN
En
Search

0.43

Engrailed

0.67	GO:0007275	multicellular organism development
0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.49	GO:1901215	negative regulation of neuron death
0.49	GO:0043523	regulation of neuron apoptotic process
0.49	GO:0060322	head development
0.47	GO:0030154	cell differentiation
0.47	GO:0043066	negative regulation of apoptotic process
0.46	GO:1902680	positive regulation of RNA biosynthetic process

0.63	GO:0043565	sequence-specific DNA binding
0.40	GO:0008094	DNA-dependent ATPase activity
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0008144	drug binding

0.60	GO:0005634	nucleus
0.43	GO:0043233	organelle lumen
0.40	GO:0043232	intracellular non-membrane-bounded organelle
0.40	GO:0044446	intracellular organelle part
0.34	GO:0030175	filopodium
0.34	GO:0030426	growth cone
0.34	GO:0030027	lamellipodium
0.30	GO:0016020	membrane

tr|Q8MXX3|Q8MXX3_CIOIN
Blcap
Search

BLCAP

0.97	Bladder cancer associated protein (Fragment)

0.58	GO:0030262	apoptotic nuclear changes
0.39	GO:0007049	cell cycle

0.33

GO:0005515

protein binding

0.30

GO:0044425

membrane part

tr|Q8SSZ0|Q8SSZ0_CIOIN
cGMP phosphodiesterase delta subunit
Search

PDE6D

0.87	cGMP phosphodiesterase delta subunit

0.75	GO:0007601	visual perception
0.46	GO:0001822	kidney development
0.45	GO:0001654	eye development
0.44	GO:0034260	negative regulation of GTPase activity
0.35	GO:0050896	response to stimulus
0.33	GO:0023052	signaling
0.33	GO:0007154	cell communication
0.33	GO:0050794	regulation of cellular process

0.76	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.45	GO:0005095	GTPase inhibitor activity
0.42	GO:0017137	Rab GTPase binding

0.40	GO:0031410	cytoplasmic vesicle
0.39	GO:0005829	cytosol
0.39	GO:0012506	vesicle membrane
0.38	GO:0005856	cytoskeleton
0.37	GO:0042995	cell projection
0.35	GO:0044446	intracellular organelle part
0.35	GO:0098590	plasma membrane region
0.35	GO:0097458	neuron part
0.34	GO:0098588	bounding membrane of organelle

0.76

EC:3.1.4.17

GO:0004114

tr|Q8T3S5|Q8T3S5_CIOIN
Casein kinase 2 alpha subunit
Search

CSNK2A1

0.77	Casein kinase II subunit alpha

0.63	GO:0006468	protein phosphorylation
0.43	GO:0030307	positive regulation of cell growth
0.42	GO:0045732	positive regulation of protein catabolic process
0.42	GO:0008284	positive regulation of cell proliferation
0.42	GO:0051336	regulation of hydrolase activity
0.41	GO:0032268	regulation of cellular protein metabolic process
0.41	GO:0035303	regulation of dephosphorylation
0.40	GO:0030177	positive regulation of Wnt signaling pathway
0.40	GO:1905818	regulation of chromosome separation
0.39	GO:0043066	negative regulation of apoptotic process

0.69	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.42	GO:0008013	beta-catenin binding
0.41	GO:0019888	protein phosphatase regulator activity
0.40	GO:0047485	protein N-terminus binding
0.37	GO:0042802	identical protein binding
0.35	GO:0043021	ribonucleoprotein complex binding

0.41	GO:0031519	PcG protein complex
0.40	GO:0005956	protein kinase CK2 complex
0.39	GO:0016580	Sin3 complex
0.39	GO:0090545	CHD-type complex
0.39	GO:0090568	nuclear transcriptional repressor complex
0.34	GO:0005829	cytosol
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.69

GO:0004674

sp|Q8T880|AXP83_CIOIN
Axonemal 84 kDa protein
Search

0.79	axonemal 84 kDa protein isoform X2

tr|Q8T883|Q8T883_CIOIN
Tektin B1
Search

TEKT2

0.97	Tektin-2 isoform A

0.80	GO:0030317	flagellated sperm motility
0.75	GO:0060271	cilium assembly
0.71	GO:0001578	microtubule bundle formation
0.70	GO:0060294	cilium movement involved in cell motility
0.61	GO:0043623	cellular protein complex assembly
0.38	GO:0080154	regulation of fertilization

0.34

GO:0005515

protein binding

0.67	GO:0015630	microtubule cytoskeleton
0.66	GO:0036126	sperm flagellum
0.62	GO:0044430	cytoskeletal part
0.51	GO:0005634	nucleus
0.47	GO:0099512	supramolecular fiber
0.38	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|Q8T885|Q8T885_CIOIN
Calcitonin gene-related peptide receptor component protein
Search

CRCP

0.94	CGRP receptor component

0.58	GO:0006351	transcription, DNA-templated
0.50	GO:0007218	neuropeptide signaling pathway
0.46	GO:0061484	hematopoietic stem cell homeostasis
0.38	GO:0045087	innate immune response
0.38	GO:0051607	defense response to virus
0.35	GO:0032481	positive regulation of type I interferon production
0.35	GO:0007568	aging
0.34	GO:0042450	arginine biosynthetic process via ornithine
0.33	GO:0006399	tRNA metabolic process
0.32	GO:0006508	proteolysis

0.70	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.55	GO:0001635	calcitonin gene-related peptide receptor activity
0.53	GO:1901265	nucleoside phosphate binding
0.51	GO:0036094	small molecule binding
0.34	GO:0004056	argininosuccinate lyase activity
0.33	GO:0005515	protein binding
0.33	GO:0004252	serine-type endopeptidase activity

0.51	GO:0001669	acrosomal vesicle
0.51	GO:0061695	transferase complex, transferring phosphorus-containing groups
0.45	GO:0044451	nucleoplasm part
0.35	GO:0005886	plasma membrane
0.35	GO:0005829	cytosol
0.35	GO:0043025	neuronal cell body
0.35	GO:0030425	dendrite
0.34	GO:0030424	axon
0.30	GO:0031224	intrinsic component of membrane

0.70

EC:2.7.7.6

GO:0003899

tr|Q8T886|Q8T886_CIOIN
Protofilament ribbon protein
Search

RIBC2

0.93	RIB43A domain with coiled-coils 2

0.72	GO:0031514	motile cilium
0.30	GO:0044425	membrane part

sp|Q8T888|DNAL1_CIOIN
Dynein light chain 1, axonemal
Search

DNAL1

0.88	Outer arm dynein light chain 2

0.83	GO:0036158	outer dynein arm assembly
0.37	GO:0035383	thioester metabolic process
0.37	GO:0016973	poly(A)+ mRNA export from nucleus
0.37	GO:0006631	fatty acid metabolic process
0.36	GO:0006732	coenzyme metabolic process
0.34	GO:0006793	phosphorus metabolic process
0.33	GO:0055114	oxidation-reduction process

0.84	GO:0045504	dynein heavy chain binding
0.82	GO:0043014	alpha-tubulin binding
0.50	GO:0003774	motor activity
0.39	GO:0047617	acyl-CoA hydrolase activity
0.37	GO:0030246	carbohydrate binding
0.34	GO:0003723	RNA binding
0.34	GO:0016491	oxidoreductase activity

0.53	GO:0030286	dynein complex
0.50	GO:0005874	microtubule
0.48	GO:0042995	cell projection
0.41	GO:0099568	cytoplasmic region
0.34	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.39

EC:3.1.2 EC:3.1.2.20

GO:0047617

tr|Q8T893|Q8T893_CIOIN
Calaxin
Search

EFCAB1

0.96	EF-hand calcium-binding domain-containing protein 1

0.35	GO:0060152	microtubule-based peroxisome localization
0.34	GO:0016558	protein import into peroxisome matrix
0.33	GO:0006468	protein phosphorylation

0.70	GO:0005509	calcium ion binding
0.34	GO:0008022	protein C-terminus binding
0.34	GO:0032403	protein complex binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0042623	ATPase activity, coupled
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0004672	protein kinase activity

0.34	GO:0031903	microbody membrane
0.34	GO:0044439	peroxisomal part
0.33	GO:0005829	cytosol

tr|Q8T894|Q8T894_CIOIN
Dynein light chain
Search

DLC

0.53	Dynein light chain

tr|Q8T8A6|Q8T8A6_CIOIN
Cysteine sulfinic acid decarboxylase
Search

GADL1

0.77	Glutamate decarboxylase like 1

0.57	GO:0019752	carboxylic acid metabolic process
0.44	GO:0035641	locomotory exploration behavior
0.43	GO:0035176	social behavior

0.67	GO:0016831	carboxy-lyase activity
0.66	GO:0030170	pyridoxal phosphate binding

0.43	GO:0060077	inhibitory synapse
0.42	GO:0043679	axon terminus
0.42	GO:0048786	presynaptic active zone
0.41	GO:0030424	axon
0.40	GO:0005938	cell cortex
0.37	GO:0005739	mitochondrion

0.67

EC:4.1.1

GO:0016831

tr|Q8TA66|Q8TA66_CIOIN
G-protein coupled receptor like protein
Search

0.86	G-protein coupled receptor like protein

0.70

GO:0007186

G-protein coupled receptor signaling pathway

0.71

GO:0004930

G-protein coupled receptor activity

0.30

GO:0044425

membrane part

tr|Q8WSS1|Q8WSS1_CIOIN
G protein alpha subunit Gi splicing variant CiGi1b
Search

GNAI2

0.75	Guanine nucleotide binding protein alpha inhibiting 2

0.82	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.50	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway
0.48	GO:0008283	cell proliferation
0.47	GO:0001973	adenosine receptor signaling pathway
0.47	GO:0007214	gamma-aminobutyric acid signaling pathway
0.47	GO:0051301	cell division
0.42	GO:0007212	dopamine receptor signaling pathway
0.42	GO:0016239	positive regulation of macroautophagy
0.40	GO:0046039	GTP metabolic process
0.38	GO:0007049	cell cycle

0.81	GO:0031683	G-protein beta/gamma-subunit complex binding
0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.64	GO:0004871	signal transducer activity
0.47	GO:0001664	G-protein coupled receptor binding
0.42	GO:0019003	GDP binding
0.36	GO:0046872	metal ion binding
0.35	GO:0032794	GTPase activating protein binding
0.34	GO:0019904	protein domain specific binding

0.54	GO:0030496	midbody
0.52	GO:0005813	centrosome
0.48	GO:0030425	dendrite
0.48	GO:0044297	cell body
0.48	GO:1905360	GTPase complex
0.47	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.47	GO:0031981	nuclear lumen
0.45	GO:0005829	cytosol
0.42	GO:0098797	plasma membrane protein complex
0.39	GO:0000139	Golgi membrane

tr|Q8WST2|Q8WST2_CIOIN
Ci-META4
Search

sp|Q94425|SYIM_CIOIN
Probable isoleucine--tRNA ligase, mitochondrial (Fragment)
Search

0.11	Probable isoleucine--tRNA ligase, mitochondrial (Fragment)

0.78	GO:0006428	isoleucyl-tRNA aminoacylation
0.73	GO:0106074	aminoacyl-tRNA metabolism involved in translational fidelity
0.33	GO:0032543	mitochondrial translation
0.33	GO:0046907	intracellular transport

0.79	GO:0004822	isoleucine-tRNA ligase activity
0.73	GO:0002161	aminoacyl-tRNA editing activity
0.67	GO:0000049	tRNA binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0008270	zinc ion binding

0.49	GO:0005737	cytoplasm
0.40	GO:0043231	intracellular membrane-bounded organelle
0.36	GO:0031974	membrane-enclosed lumen
0.34	GO:0044446	intracellular organelle part

0.79	EC:6.1.1.5	GO:0004822
0.79	KEGG:R03656	GO:0004822

tr|Q95P33|Q95P33_CIOIN
Opsin
Search

0.82	Visible light sensitive parapinopsin

0.76	GO:0007602	phototransduction
0.75	GO:0007601	visual perception
0.74	GO:0018298	protein-chromophore linkage
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.53	GO:0016038	absorption of visible light
0.45	GO:0009584	detection of visible light
0.38	GO:0071482	cellular response to light stimulus
0.34	GO:0045494	photoreceptor cell maintenance
0.34	GO:0001523	retinoid metabolic process
0.34	GO:0060041	retina development in camera-type eye

0.78	GO:0009881	photoreceptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.38	GO:0005502	11-cis retinal binding
0.32	GO:0046872	metal ion binding

0.48	GO:0001750	photoreceptor outer segment
0.39	GO:0060170	ciliary membrane
0.36	GO:0060342	photoreceptor inner segment membrane
0.34	GO:0005887	integral component of plasma membrane
0.33	GO:0005911	cell-cell junction
0.33	GO:0005794	Golgi apparatus

sp|Q95YJ5|TXND3_CIOIN
Thioredoxin domain-containing protein 3 homolog
Search

0.35	Nucleoside diphosphate kinase

0.78	GO:0006228	UTP biosynthetic process
0.78	GO:0006183	GTP biosynthetic process
0.74	GO:0046036	CTP metabolic process
0.69	GO:0006165	nucleoside diphosphate phosphorylation
0.63	GO:0045454	cell redox homeostasis
0.49	GO:0007283	spermatogenesis
0.47	GO:0022412	cellular process involved in reproduction in multicellular organism
0.46	GO:0030154	cell differentiation
0.46	GO:0003006	developmental process involved in reproduction
0.45	GO:1902176	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway

0.78	GO:0004550	nucleoside diphosphate kinase activity
0.35	GO:0004563	beta-N-acetylhexosaminidase activity
0.35	GO:0030246	carbohydrate binding
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0005515	protein binding
0.31	GO:0046872	metal ion binding
0.31	GO:0003676	nucleic acid binding

0.44	GO:0036126	sperm flagellum
0.35	GO:0005622	intracellular
0.33	GO:1902493	acetyltransferase complex
0.32	GO:0031974	membrane-enclosed lumen
0.32	GO:1904949	ATPase complex
0.32	GO:0043227	membrane-bounded organelle
0.32	GO:0043234	protein complex
0.32	GO:0043228	non-membrane-bounded organelle
0.32	GO:0044422	organelle part
0.30	GO:0016021	integral component of membrane

0.78

EC:2.7.4.6

GO:0004550

tr|Q967X2|Q967X2_CIOIN
Casein kinase II subunit beta
Search

CSNK2B

0.59	Casein kinase II subunit beta

0.76	GO:0045859	regulation of protein kinase activity
0.51	GO:0033211	adiponectin-activated signaling pathway
0.51	GO:0032927	positive regulation of activin receptor signaling pathway
0.51	GO:0016310	phosphorylation
0.51	GO:0061154	endothelial tube morphogenesis
0.50	GO:0043537	negative regulation of blood vessel endothelial cell migration
0.49	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
0.48	GO:0018210	peptidyl-threonine modification
0.41	GO:0016055	Wnt signaling pathway
0.38	GO:0097421	liver regeneration

0.79	GO:0019887	protein kinase regulator activity
0.52	GO:0016301	kinase activity
0.46	GO:0003682	chromatin binding
0.46	GO:0019904	protein domain specific binding
0.45	GO:0042802	identical protein binding
0.45	GO:0008134	transcription factor binding
0.45	GO:0005102	receptor binding
0.41	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.40	GO:0140096	catalytic activity, acting on a protein
0.36	GO:0043021	ribonucleoprotein complex binding

0.83	GO:0005956	protein kinase CK2 complex
0.50	GO:0031519	PcG protein complex
0.39	GO:0005886	plasma membrane
0.37	GO:0016363	nuclear matrix
0.37	GO:0005737	cytoplasm
0.36	GO:0005929	cilium
0.36	GO:0000785	chromatin
0.36	GO:0070062	extracellular exosome
0.35	GO:0031983	vesicle lumen
0.33	GO:0097708	intracellular vesicle

0.41

EC:2.7.1

GO:0016773

tr|Q9NDP3|Q9NDP3_CIOIN
Not7
Search

0.78	BHLH transcription factor MAD

0.46	GO:0000122	negative regulation of transcription by RNA polymerase II
0.34	GO:0042994	cytoplasmic sequestering of transcription factor
0.34	GO:0008285	negative regulation of cell proliferation
0.34	GO:0006351	transcription, DNA-templated

0.68	GO:0046983	protein dimerization activity
0.46	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.34	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.34	GO:0003714	transcription corepressor activity

0.45	GO:0090575	RNA polymerase II transcription factor complex
0.44	GO:0005730	nucleolus
0.43	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

tr|Q9NDQ5|Q9NDQ5_CIOIN
Hexosyltransferase
Search

0.47	Hexosyltransferase

0.74

GO:0006486

protein glycosylation

0.81

GO:0008378

galactosyltransferase activity

0.74	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

0.81

GO:0008378

tr|Q9NL28|Q9NL28_CIOIN
Netrin
Search

0.70	netrin precursor

0.46	GO:0040012	regulation of locomotion
0.46	GO:0000904	cell morphogenesis involved in differentiation
0.45	GO:0050772	positive regulation of axonogenesis
0.45	GO:0097485	neuron projection guidance
0.45	GO:0051270	regulation of cellular component movement
0.45	GO:0016477	cell migration
0.45	GO:0061564	axon development
0.44	GO:0009887	animal organ morphogenesis
0.42	GO:0007155	cell adhesion
0.42	GO:0045138	nematode male tail tip morphogenesis

0.37	GO:0005201	extracellular matrix structural constituent
0.36	GO:0005102	receptor binding
0.35	GO:0004871	signal transducer activity
0.34	GO:0005230	extracellular ligand-gated ion channel activity
0.34	GO:0099600	transmembrane receptor activity
0.34	GO:0017022	myosin binding
0.34	GO:0005518	collagen binding
0.33	GO:0042803	protein homodimerization activity
0.33	GO:0004672	protein kinase activity
0.32	GO:0030554	adenyl nucleotide binding

0.64	GO:0005576	extracellular region
0.40	GO:0030424	axon
0.35	GO:0005737	cytoplasm
0.34	GO:0060171	stereocilium membrane
0.34	GO:0002142	stereocilia ankle link complex
0.34	GO:1990696	USH2 complex
0.34	GO:1990075	periciliary membrane compartment
0.34	GO:0001917	photoreceptor inner segment
0.34	GO:0032391	photoreceptor connecting cilium
0.34	GO:0036064	ciliary basal body

tr|Q9NL43|Q9NL43_CIOIN
Glycogen synthase kinase
Search

0.82	Glycogen synthase kinase

0.63	GO:0006468	protein phosphorylation
0.54	GO:0010822	positive regulation of mitochondrion organization
0.53	GO:0003007	heart morphogenesis
0.53	GO:0036015	response to interleukin-3
0.53	GO:0018209	peptidyl-serine modification
0.52	GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development
0.52	GO:0044027	hypermethylation of CpG island
0.52	GO:2000467	positive regulation of glycogen (starch) synthase activity
0.52	GO:0106071	positive regulation of adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.52	GO:0071879	positive regulation of adrenergic receptor signaling pathway

0.69	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.50	GO:0050321	tau-protein kinase activity
0.49	GO:0034236	protein kinase A catalytic subunit binding
0.48	GO:0034452	dynactin binding
0.47	GO:0051059	NF-kappaB binding
0.46	GO:0002039	p53 binding

0.47	GO:0030877	beta-catenin destruction complex
0.44	GO:0005813	centrosome
0.42	GO:0043231	intracellular membrane-bounded organelle
0.38	GO:0005886	plasma membrane
0.36	GO:0043025	neuronal cell body
0.36	GO:0030425	dendrite
0.35	GO:0098794	postsynapse
0.35	GO:0005829	cytosol
0.35	GO:1990909	Wnt signalosome
0.35	GO:0005874	microtubule

0.69