Queries 24001 to 24177

GO:0016491

tr|Q6P634|Q6P634_XENTR
Sp5 transcription factor
Search

SP5

0.97	Zinc finger containing transactivation factor Sp5

0.52	GO:0036342	post-anal tail morphogenesis
0.52	GO:0048332	mesoderm morphogenesis
0.47	GO:0048513	animal organ development
0.46	GO:0006357	regulation of transcription by RNA polymerase II
0.46	GO:0001501	skeletal system development
0.44	GO:0071407	cellular response to organic cyclic compound
0.43	GO:0045892	negative regulation of transcription, DNA-templated
0.42	GO:0048598	embryonic morphogenesis
0.41	GO:0009952	anterior/posterior pattern specification
0.41	GO:0048646	anatomical structure formation involved in morphogenesis

0.51	GO:0003676	nucleic acid binding
0.45	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.36	GO:0003682	chromatin binding
0.33	GO:0061630	ubiquitin protein ligase activity
0.33	GO:0046872	metal ion binding

0.41	GO:0005634	nucleus
0.36	GO:0017053	transcriptional repressor complex

sp|Q6P635|CSN5_XENTR
COP9 signalosome complex subunit 5
Search

COPS5

0.85	COP9 constitutive photomorphogenic homolog subunit 5

0.58	GO:1990182	exosomal secretion
0.58	GO:1903894	regulation of IRE1-mediated unfolded protein response
0.58	GO:0006508	proteolysis
0.55	GO:0051091	positive regulation of DNA binding transcription factor activity
0.54	GO:0046328	regulation of JNK cascade
0.53	GO:0043066	negative regulation of apoptotic process
0.50	GO:0045944	positive regulation of transcription by RNA polymerase II
0.50	GO:0051726	regulation of cell cycle
0.49	GO:0070647	protein modification by small protein conjugation or removal
0.36	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c

0.66	GO:0004222	metalloendopeptidase activity
0.60	GO:0035718	macrophage migration inhibitory factor binding
0.52	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.49	GO:0019899	enzyme binding
0.36	GO:0003713	transcription coactivator activity
0.35	GO:0019784	NEDD8-specific protease activity
0.35	GO:0046872	metal ion binding
0.35	GO:0046983	protein dimerization activity
0.34	GO:0003743	translation initiation factor activity

0.76	GO:0008180	COP9 signalosome
0.55	GO:0008021	synaptic vesicle
0.49	GO:0000785	chromatin
0.48	GO:0005829	cytosol
0.48	GO:0005654	nucleoplasm
0.40	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0030054	cell junction
0.34	GO:0005852	eukaryotic translation initiation factor 3 complex
0.34	GO:0005667	transcription factor complex
0.33	GO:0005739	mitochondrion

0.66

EC:3.4.24

GO:0004222

sp|Q6P637|CSN8_XENTR
COP9 signalosome complex subunit 8
Search

COPS8

0.93	COP9 constitutive photomorphogenic homolog subunit 8

0.86	GO:0010387	COP9 signalosome assembly
0.83	GO:0000338	protein deneddylation
0.55	GO:0007250	activation of NF-kappaB-inducing kinase activity
0.51	GO:0008285	negative regulation of cell proliferation
0.35	GO:0043687	post-translational protein modification
0.34	GO:0000715	nucleotide-excision repair, DNA damage recognition
0.34	GO:0006283	transcription-coupled nucleotide-excision repair
0.34	GO:0006413	translational initiation
0.32	GO:0006396	RNA processing

0.34	GO:0003743	translation initiation factor activity
0.34	GO:0008270	zinc ion binding
0.33	GO:0005515	protein binding
0.32	GO:0016874	ligase activity

0.80	GO:0008180	COP9 signalosome
0.51	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0005654	nucleoplasm
0.47	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.32

EC:6

GO:0016874

tr|Q6P639|Q6P639_XENTR
60S ribosomal protein L13
Search

RPL13

0.68	Ribosomal protein L13

0.60	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.41	GO:0051726	regulation of cell cycle
0.35	GO:0097421	liver regeneration
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006508	proteolysis
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription

0.63	GO:0003735	structural constituent of ribosome
0.40	GO:0003723	RNA binding
0.36	GO:0004222	metalloendopeptidase activity
0.34	GO:0005515	protein binding
0.34	GO:0008270	zinc ion binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005840	ribosome
0.47	GO:0005829	cytosol
0.44	GO:0005730	nucleolus
0.44	GO:0005783	endoplasmic reticulum
0.30	GO:0016020	membrane

0.36

EC:3.4.24

GO:0004222

sp|Q6P640|ACTC_XENTR
Actin, alpha cardiac muscle 1
Search

ACTC1

0.83	Actin aortic smooth muscle

0.78	GO:0090131	mesenchyme migration
0.63	GO:0010628	positive regulation of gene expression
0.57	GO:0030240	skeletal muscle thin filament assembly
0.56	GO:0033275	actin-myosin filament sliding
0.55	GO:0055003	cardiac myofibril assembly
0.54	GO:0055008	cardiac muscle tissue morphogenesis
0.54	GO:0060047	heart contraction
0.50	GO:0043066	negative regulation of apoptotic process
0.43	GO:0006936	muscle contraction
0.43	GO:0072144	glomerular mesangial cell development

0.53	GO:0017022	myosin binding
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0016887	ATPase activity
0.40	GO:0019901	protein kinase binding
0.34	GO:0005200	structural constituent of cytoskeleton

0.73	GO:0030175	filopodium
0.71	GO:0030027	lamellipodium
0.70	GO:0044297	cell body
0.56	GO:0042643	actomyosin, actin portion
0.54	GO:0044449	contractile fiber part
0.52	GO:0030016	myofibril
0.38	GO:0097517	contractile actin filament bundle
0.38	GO:0070062	extracellular exosome
0.36	GO:0043234	protein complex
0.36	GO:0072562	blood microparticle

0.43

GO:0016887

sp|Q6P642|DNJB6_XENTR
DnaJ homolog subfamily B member 6
Search

DNAJB6

0.79	DnaJ like protein subfamily B member 6

0.77	GO:0090084	negative regulation of inclusion body assembly
0.61	GO:0045109	intermediate filament organization
0.60	GO:0006457	protein folding
0.59	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.57	GO:0032781	positive regulation of ATPase activity
0.53	GO:0032880	regulation of protein localization
0.53	GO:0060715	syncytiotrophoblast cell differentiation involved in labyrinthine layer development
0.52	GO:0060710	chorio-allantoic fusion
0.52	GO:0060717	chorion development
0.48	GO:0030036	actin cytoskeleton organization

0.66	GO:0051087	chaperone binding
0.63	GO:0044183	protein binding involved in protein folding
0.61	GO:0051082	unfolded protein binding
0.57	GO:0001671	ATPase activator activity
0.55	GO:0031072	heat shock protein binding
0.44	GO:0042802	identical protein binding
0.39	GO:0003677	DNA binding

0.65	GO:0048471	perinuclear region of cytoplasm
0.64	GO:0030018	Z disc
0.60	GO:0005634	nucleus
0.59	GO:0005829	cytosol
0.50	GO:0031974	membrane-enclosed lumen
0.46	GO:0044446	intracellular organelle part
0.39	GO:0012505	endomembrane system
0.37	GO:0031975	envelope
0.30	GO:0016020	membrane

sp|Q6P643|THOC7_XENTR
THO complex subunit 7 homolog
Search

THOC7

0.95	THO complex subunit 7

0.67	GO:0006397	mRNA processing
0.56	GO:0046784	viral mRNA export from host cell nucleus
0.54	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.52	GO:0051028	mRNA transport
0.51	GO:0006405	RNA export from nucleus
0.39	GO:0008380	RNA splicing
0.35	GO:0006369	termination of RNA polymerase II transcription
0.34	GO:0031123	RNA 3'-end processing

0.36	GO:0003723	RNA binding
0.34	GO:0005515	protein binding

0.82	GO:0000445	THO complex part of transcription export complex
0.53	GO:0000781	chromosome, telomeric region
0.52	GO:0016607	nuclear speck
0.48	GO:0044454	nuclear chromosome part
0.46	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|Q6P647|KC1D_XENTR
Casein kinase I isoform delta
Search

CSNK1D

0.73	Casein kinase I

0.63	GO:0006468	protein phosphorylation
0.52	GO:2000052	positive regulation of non-canonical Wnt signaling pathway
0.51	GO:0018209	peptidyl-serine modification
0.51	GO:0032922	circadian regulation of gene expression
0.51	GO:0071539	protein localization to centrosome
0.51	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.51	GO:0061512	protein localization to cilium
0.50	GO:1905515	non-motile cilium assembly
0.50	GO:0042752	regulation of circadian rhythm
0.50	GO:0034067	protein localization to Golgi apparatus

0.63	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0045296	cadherin binding
0.37	GO:0042277	peptide binding

0.49	GO:0005876	spindle microtubule
0.48	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0005813	centrosome
0.45	GO:0005794	Golgi apparatus
0.44	GO:0005634	nucleus
0.40	GO:0005886	plasma membrane
0.37	GO:0043005	neuron projection
0.35	GO:0098588	bounding membrane of organelle
0.35	GO:0005829	cytosol
0.35	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment

tr|Q6P648|Q6P648_XENTR
DDB1 and CUL4-associated factor 7
Search

DCAF7

0.94	WD repeat-containing protein 68

0.56	GO:0048703	embryonic viscerocranium morphogenesis
0.54	GO:0051216	cartilage development
0.48	GO:0048627	myoblast development
0.48	GO:0035332	positive regulation of hippo signaling
0.46	GO:0048747	muscle fiber development
0.45	GO:0045927	positive regulation of growth
0.45	GO:0007517	muscle organ development
0.39	GO:0016567	protein ubiquitination
0.37	GO:0043687	post-translational protein modification
0.37	GO:0016573	histone acetylation

0.40	GO:0008241	peptidyl-dipeptidase activity
0.38	GO:0004180	carboxypeptidase activity
0.38	GO:0005515	protein binding
0.37	GO:0008237	metallopeptidase activity
0.37	GO:0004402	histone acetyltransferase activity
0.35	GO:0005249	voltage-gated potassium channel activity
0.35	GO:0016875	ligase activity, forming carbon-oxygen bonds
0.35	GO:0140101	catalytic activity, acting on a tRNA
0.35	GO:0030554	adenyl nucleotide binding
0.35	GO:0004672	protein kinase activity

0.70	GO:0016363	nuclear matrix
0.70	GO:0080008	Cul4-RING E3 ubiquitin ligase complex
0.65	GO:0016604	nuclear body
0.58	GO:0005829	cytosol
0.51	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.40

EC:3.4.15

GO:0008241

tr|Q6P650|Q6P650_XENTR
Stress-associated endoplasmic reticulum protein 1
Search

SERP1

0.84	Stress-associated endoplasmic reticulum protein 1

0.61	GO:0015031	protein transport
0.53	GO:0030968	endoplasmic reticulum unfolded protein response
0.50	GO:0060124	positive regulation of growth hormone secretion
0.48	GO:0046622	positive regulation of organ growth
0.48	GO:0032024	positive regulation of insulin secretion
0.48	GO:0048644	muscle organ morphogenesis
0.48	GO:0010259	multicellular organism aging
0.46	GO:0001501	skeletal system development
0.46	GO:0043413	macromolecule glycosylation
0.46	GO:0009101	glycoprotein biosynthetic process

0.34	GO:0005515	protein binding
0.34	GO:0003735	structural constituent of ribosome

0.70	GO:0005783	endoplasmic reticulum
0.66	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.63	GO:0031984	organelle subcompartment
0.48	GO:0005881	cytoplasmic microtubule
0.34	GO:0015935	small ribosomal subunit
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q6P7K0|CMBL_XENTR
Carboxymethylenebutenolidase homolog
Search

CMBL

0.56	Carboxymethylenebutenolidase

0.34	GO:0006805	xenobiotic metabolic process
0.33	GO:0006468	protein phosphorylation

0.51	GO:0016787	hydrolase activity
0.33	GO:0004672	protein kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.38	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.51

GO:0016787

tr|Q6P7K1|Q6P7K1_XENTR
Electron transfer flavoprotein beta subunit
Search

ETFB

0.86	Electron-transfer-flavoprotein beta polypeptide

0.61

GO:0022900

electron transport chain

0.62

GO:0009055

electron transfer activity

0.42

GO:0005829

cytosol

tr|Q6P7K2|Q6P7K2_XENTR
40S ribosomal protein S6
Search

RPS6

0.64	Ribosomal protein S6 (Fragment)

0.60	GO:0006518	peptide metabolic process
0.59	GO:0043604	amide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.54	GO:1901566	organonitrogen compound biosynthetic process
0.54	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.52	GO:0002309	T cell proliferation involved in immune response
0.51	GO:0022605	oogenesis stage
0.51	GO:0006924	activation-induced cell death of T cells
0.50	GO:0042274	ribosomal small subunit biogenesis

0.64	GO:0003735	structural constituent of ribosome
0.46	GO:0019901	protein kinase binding
0.34	GO:0003729	mRNA binding

0.61	GO:0005840	ribosome
0.50	GO:0030425	dendrite
0.49	GO:0044445	cytosolic part
0.48	GO:0005844	polysome
0.48	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0044297	cell body
0.47	GO:0036464	cytoplasmic ribonucleoprotein granule
0.45	GO:0005730	nucleolus
0.44	GO:0005783	endoplasmic reticulum
0.33	GO:0005654	nucleoplasm

sp|Q6P7K5|EMC10_XENTR
ER membrane protein complex subunit 10
Search

EMC10

0.97	LOW QUALITY PROTEIN: ER membrane protein complex subunit 10

0.34

GO:0006334

nucleosome assembly

0.32

GO:0003677

DNA binding

0.61	GO:0072546	ER membrane protein complex
0.41	GO:0005774	vacuolar membrane
0.36	GO:0005576	extracellular region
0.34	GO:0000786	nucleosome

sp|Q6P7L0|C10_XENTR
Protein C10
Search

0.97	Gene-rich cluster, C10 gene

0.85	GO:0036343	psychomotor behavior
0.85	GO:0021678	third ventricle development
0.84	GO:0021540	corpus callosum morphogenesis
0.83	GO:0014819	regulation of skeletal muscle contraction
0.77	GO:0048593	camera-type eye morphogenesis
0.75	GO:0050890	cognition
0.72	GO:0009791	post-embryonic development

0.74	GO:0016607	nuclear speck
0.48	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q6P7L4|SC22B_XENTR
Vesicle-trafficking protein SEC22b
Search

SEC22B

0.94	SEC22 vesicle trafficking protein homolog B (S. cerevisiae)

0.67	GO:0016192	vesicle-mediated transport
0.56	GO:1902902	negative regulation of autophagosome assembly
0.52	GO:0045732	positive regulation of protein catabolic process
0.48	GO:0090174	organelle membrane fusion
0.47	GO:0016050	vesicle organization
0.43	GO:0032940	secretion by cell
0.43	GO:0046907	intracellular transport
0.39	GO:0015031	protein transport
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.34	GO:0051650	establishment of vesicle localization

0.47	GO:0000149	SNARE binding
0.47	GO:0005484	SNAP receptor activity

0.55	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.52	GO:0012507	ER to Golgi transport vesicle membrane
0.48	GO:0005789	endoplasmic reticulum membrane
0.48	GO:0005794	Golgi apparatus
0.48	GO:0031201	SNARE complex
0.43	GO:0042470	melanosome
0.35	GO:0030670	phagocytic vesicle membrane
0.34	GO:0070382	exocytic vesicle
0.30	GO:0016021	integral component of membrane

sp|Q6P7L9|EIF3E_XENTR
Eukaryotic translation initiation factor 3 subunit E
Search

EIF3E

0.69	Eukaryotic translation initiation factor 3 subunit E-B

0.72	GO:0001731	formation of translation preinitiation complex
0.71	GO:0006446	regulation of translational initiation
0.54	GO:1902416	positive regulation of mRNA binding
0.52	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.49	GO:0045727	positive regulation of translation
0.34	GO:0017148	negative regulation of translation

0.72	GO:0003743	translation initiation factor activity
0.52	GO:0047485	protein N-terminus binding
0.50	GO:0045296	cadherin binding

0.77	GO:0005852	eukaryotic translation initiation factor 3 complex
0.72	GO:0016282	eukaryotic 43S preinitiation complex
0.72	GO:0033290	eukaryotic 48S preinitiation complex
0.58	GO:0005634	nucleus
0.45	GO:0005829	cytosol
0.45	GO:0043233	organelle lumen
0.41	GO:0044446	intracellular organelle part
0.34	GO:0070062	extracellular exosome
0.33	GO:0005694	chromosome
0.30	GO:0016020	membrane

tr|Q6P7M0|Q6P7M0_XENTR
Annexin
Search

ANXA2

0.60

Annexin

0.71	GO:0043086	negative regulation of catalytic activity
0.58	GO:0052362	catabolism by host of symbiont protein
0.58	GO:0044147	negative regulation of development of symbiont involved in interaction with host
0.58	GO:1905597	positive regulation of low-density lipoprotein particle receptor binding
0.58	GO:1905599	positive regulation of low-density lipoprotein receptor activity
0.58	GO:1905581	positive regulation of low-density lipoprotein particle clearance
0.57	GO:1905602	positive regulation of receptor-mediated endocytosis involved in cholesterol transport
0.57	GO:0032804	negative regulation of low-density lipoprotein particle receptor catabolic process
0.56	GO:0036035	osteoclast development
0.56	GO:0052405	negative regulation by host of symbiont molecular function

0.85	GO:0004859	phospholipase inhibitor activity
0.81	GO:0005544	calcium-dependent phospholipid binding
0.71	GO:0008092	cytoskeletal protein binding
0.69	GO:0005509	calcium ion binding
0.55	GO:0098641	cadherin binding involved in cell-cell adhesion
0.55	GO:0044548	S100 protein binding
0.54	GO:0048306	calcium-dependent protein binding
0.53	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.53	GO:0002020	protease binding
0.48	GO:0042802	identical protein binding

0.57	GO:1990667	PCSK9-AnxA2 complex
0.53	GO:0035749	myelin sheath adaxonal region
0.53	GO:0005913	cell-cell adherens junction
0.52	GO:0031902	late endosome membrane
0.52	GO:0030496	midbody
0.52	GO:0005811	lipid droplet
0.52	GO:0043220	Schmidt-Lanterman incisure
0.52	GO:0070062	extracellular exosome
0.52	GO:0005765	lysosomal membrane
0.51	GO:0098857	membrane microdomain

tr|Q6P7M4|Q6P7M4_XENTR
B-cell translocation gene 1, anti-proliferative
Search

BTG1

0.96	B-cell translocation protein 1, anti-proliferative

0.79	GO:0008285	negative regulation of cell proliferation
0.56	GO:2000271	positive regulation of fibroblast apoptotic process
0.55	GO:0045603	positive regulation of endothelial cell differentiation
0.53	GO:0045663	positive regulation of myoblast differentiation
0.52	GO:0045766	positive regulation of angiogenesis
0.51	GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
0.51	GO:0021542	dentate gyrus development
0.49	GO:0035914	skeletal muscle cell differentiation
0.49	GO:0008306	associative learning
0.49	GO:0021954	central nervous system neuron development

0.47	GO:0019899	enzyme binding
0.38	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.34	GO:0003712	transcription cofactor activity

0.43	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm
0.35	GO:0070062	extracellular exosome

tr|Q6P7M5|Q6P7M5_XENTR
Nucleoside diphosphate kinase
Search

NME7

0.54	Non-metastatic cells 7, protein expressed in (Nucleoside-diphosphate kinase)

0.79	GO:0006228	UTP biosynthetic process
0.79	GO:0006183	GTP biosynthetic process
0.75	GO:0046036	CTP metabolic process
0.70	GO:0006165	nucleoside diphosphate phosphorylation

0.79	GO:0004550	nucleoside diphosphate kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.58

GO:0005813

centrosome

0.79

EC:2.7.4.6

GO:0004550

tr|Q6P7M6|Q6P7M6_XENTR
ADP ribosylation factor-like GTPase 2
Search

ARL2

0.83	ADP ribosylation factor like GTPase 2

0.47	GO:0051457	maintenance of protein location in nucleus
0.47	GO:0034260	negative regulation of GTPase activity
0.46	GO:0031116	positive regulation of microtubule polymerization
0.45	GO:0007098	centrosome cycle
0.39	GO:0070830	bicellular tight junction assembly
0.39	GO:0010811	positive regulation of cell-substrate adhesion
0.37	GO:0045196	establishment or maintenance of neuroblast polarity
0.36	GO:0000132	establishment of mitotic spindle orientation
0.35	GO:0010817	regulation of hormone levels
0.35	GO:1901374	acetate ester transport

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0003924	GTPase activity
0.35	GO:0005515	protein binding
0.35	GO:0005095	GTPase inhibitor activity
0.32	GO:0016491	oxidoreductase activity

0.45	GO:0005622	intracellular
0.45	GO:0005925	focal adhesion
0.41	GO:0012505	endomembrane system
0.41	GO:0031974	membrane-enclosed lumen
0.39	GO:0016328	lateral plasma membrane
0.39	GO:0031975	envelope
0.39	GO:0043228	non-membrane-bounded organelle
0.38	GO:0044422	organelle part
0.38	GO:0043227	membrane-bounded organelle
0.36	GO:0043230	extracellular organelle

0.32

GO:0016491

tr|Q6P7N0|Q6P7N0_XENTR
Solute carrier family 25 (Mitochondrial carrier adenine nucleotide translocator), member 4
Search

SLC25A4

0.90	Mitochondrial ADP/ATP translocase 1

0.57	GO:0015866	ADP transport
0.55	GO:0055085	transmembrane transport
0.53	GO:0060546	negative regulation of necroptotic process
0.52	GO:0007005	mitochondrion organization
0.52	GO:0090559	regulation of membrane permeability
0.51	GO:0015867	ATP transport
0.49	GO:0006915	apoptotic process
0.48	GO:0006839	mitochondrial transport
0.45	GO:0061024	membrane organization
0.37	GO:0015853	adenine transport

0.57	GO:0022857	transmembrane transporter activity
0.36	GO:0005515	protein binding
0.33	GO:0047429	nucleoside-triphosphate diphosphatase activity
0.33	GO:0008171	O-methyltransferase activity

0.62	GO:0005743	mitochondrial inner membrane
0.50	GO:0043209	myelin sheath
0.38	GO:0032592	integral component of mitochondrial membrane
0.35	GO:0005741	mitochondrial outer membrane
0.35	GO:0071817	MMXD complex
0.34	GO:0042645	mitochondrial nucleoid
0.34	GO:0098857	membrane microdomain
0.34	GO:0005634	nucleus
0.34	GO:0098798	mitochondrial protein complex
0.34	GO:0031012	extracellular matrix

0.33

EC:3.6.1.19

GO:0047429

sp|Q6P7N1|MAK16_XENTR
Protein MAK16 homolog
Search

0.10	Putative rna-binding nuclear protein mak16 (Fragment)

0.49	GO:0000470	maturation of LSU-rRNA
0.48	GO:0000460	maturation of 5.8S rRNA
0.34	GO:0007275	multicellular organism development

0.34

GO:0003723

RNA binding

0.70	GO:0005730	nucleolus
0.48	GO:0030687	preribosome, large subunit precursor
0.36	GO:0005840	ribosome

sp|Q6P7N4|HMCES_XENTR
Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein
Search

HMCES

0.97	Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein (Fragment)

0.59	GO:0006508	proteolysis
0.33	GO:0006886	intracellular protein transport
0.33	GO:0016192	vesicle-mediated transport

0.60	GO:0008233	peptidase activity
0.36	GO:0003677	DNA binding

0.34	GO:0048475	coated membrane
0.33	GO:0098796	membrane protein complex
0.32	GO:0044444	cytoplasmic part

0.60

EC:3.4

GO:0008233

tr|Q6P7Y4|Q6P7Y4_XENTR
Signal peptidase complex catalytic subunit SEC11
Search

SEC11A

0.72	Signal peptidase complex catalytic subunit SEC11

0.80

GO:0006465

signal peptide processing

0.67

GO:0008236

serine-type peptidase activity

0.82	GO:0005787	signal peptidase complex
0.38	GO:0031090	organelle membrane
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

tr|Q6P7Z3|Q6P7Z3_XENTR
Proteasome subunit alpha type
Search

PSMA6

0.49	Proteasome endopeptidase complex

0.72	GO:0051603	proteolysis involved in cellular protein catabolic process
0.68	GO:0043632	modification-dependent macromolecule catabolic process
0.51	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.39	GO:0071346	cellular response to interferon-gamma
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.35	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation

0.77	GO:0004298	threonine-type endopeptidase activity
0.53	GO:0051059	NF-kappaB binding
0.42	GO:0003723	RNA binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.79	GO:0019773	proteasome core complex, alpha-subunit complex
0.58	GO:0005634	nucleus
0.51	GO:0005844	polysome
0.50	GO:0000932	P-body
0.45	GO:0070013	intracellular organelle lumen
0.41	GO:0044446	intracellular organelle part
0.37	GO:0030017	sarcomere
0.36	GO:0070062	extracellular exosome
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.77

EC:3.4.25

GO:0004298

tr|Q6P7Z6|Q6P7Z6_XENTR
ADP ribosylation factor 5
Search

ARF1

0.76	ADP ribosylation factor 5

0.53	GO:1990386	mitotic cleavage furrow ingression
0.50	GO:0016192	vesicle-mediated transport
0.49	GO:0098586	cellular response to virus
0.47	GO:0006878	cellular copper ion homeostasis
0.42	GO:0060292	long term synaptic depression
0.41	GO:0097061	dendritic spine organization
0.41	GO:0002090	regulation of receptor internalization
0.41	GO:1903337	positive regulation of vacuolar transport
0.41	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation
0.40	GO:1902822	regulation of late endosome to lysosome transport

0.64	GO:0005525	GTP binding
0.46	GO:0019904	protein domain specific binding
0.45	GO:0046982	protein heterodimerization activity
0.42	GO:0000287	magnesium ion binding
0.41	GO:1990583	phospholipase D activator activity
0.39	GO:0019003	GDP binding
0.34	GO:0003924	GTPase activity
0.34	GO:0005057	signal transducer activity, downstream of receptor
0.34	GO:0003723	RNA binding

0.51	GO:0005794	Golgi apparatus
0.48	GO:0030017	sarcomere
0.47	GO:0031252	cell leading edge
0.44	GO:0005829	cytosol
0.42	GO:0048471	perinuclear region of cytoplasm
0.41	GO:0043234	protein complex
0.39	GO:0014069	postsynaptic density
0.39	GO:0031982	vesicle
0.39	GO:0043230	extracellular organelle
0.39	GO:0045211	postsynaptic membrane

tr|Q6P7Z7|Q6P7Z7_XENTR
RAB35, member RAS oncogene family
Search

RAB35

0.96	RAB35 member RAS oncogene family

0.55	GO:0048227	plasma membrane to endosome transport
0.54	GO:0036010	protein localization to endosome
0.53	GO:0016197	endosomal transport
0.51	GO:0000281	mitotic cytokinesis
0.49	GO:0031175	neuron projection development
0.49	GO:0019882	antigen processing and presentation
0.39	GO:1990090	cellular response to nerve growth factor stimulus
0.35	GO:0015031	protein transport
0.34	GO:0033674	positive regulation of kinase activity
0.34	GO:0045859	regulation of protein kinase activity

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.36	GO:0071532	ankyrin repeat binding
0.36	GO:0032794	GTPase activating protein binding
0.34	GO:0019887	protein kinase regulator activity
0.34	GO:0019901	protein kinase binding

0.52	GO:0045171	intercellular bridge
0.52	GO:0045334	clathrin-coated endocytic vesicle
0.51	GO:0031253	cell projection membrane
0.50	GO:0005905	clathrin-coated pit
0.47	GO:0010008	endosome membrane
0.43	GO:0005739	mitochondrion
0.40	GO:0098993	anchored component of synaptic vesicle membrane
0.38	GO:0042470	melanosome
0.37	GO:0055037	recycling endosome
0.36	GO:0070062	extracellular exosome

tr|Q6P802|Q6P802_XENTR
Acetyl-CoA acetyltransferase 2
Search

ACAT2

0.94	Mitochondrial trifunctional protein beta subunit

0.46	GO:0006635	fatty acid beta-oxidation
0.39	GO:0045797	positive regulation of intestinal cholesterol absorption
0.37	GO:0080009	mRNA methylation
0.36	GO:0006695	cholesterol biosynthetic process
0.35	GO:0019408	dolichol biosynthetic process
0.35	GO:0071398	cellular response to fatty acid
0.34	GO:0001889	liver development
0.34	GO:0031670	cellular response to nutrient
0.34	GO:0046952	ketone body catabolic process
0.34	GO:0007420	brain development

0.64	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
0.33	GO:0005515	protein binding

0.48	GO:0005730	nucleolus
0.47	GO:0005829	cytosol
0.41	GO:0005739	mitochondrion
0.36	GO:0070062	extracellular exosome
0.35	GO:0005777	peroxisome

0.64

EC:2.3.1

GO:0016747

sp|Q6P806|SAM50_XENTR
Sorting and assembly machinery component 50 homolog
Search

SAMM50

0.96	Sorting and assembly machinery component 50

0.54	GO:0042407	cristae formation
0.51	GO:0045040	protein import into mitochondrial outer membrane
0.50	GO:0033108	mitochondrial respiratory chain complex assembly
0.35	GO:0001889	liver development
0.32	GO:0006629	lipid metabolic process

0.34	GO:0005515	protein binding
0.33	GO:0005509	calcium ion binding

0.66	GO:0019867	outer membrane
0.48	GO:0098805	whole membrane
0.47	GO:0098588	bounding membrane of organelle
0.47	GO:0098798	mitochondrial protein complex
0.47	GO:0044455	mitochondrial membrane part
0.42	GO:0098796	membrane protein complex
0.42	GO:0019866	organelle inner membrane
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

sp|Q6P809|DCA12_XENTR
DDB1- and CUL4-associated factor 12
Search

DCAF12

0.60	WD repeat-containing protein 40A

0.50

GO:0016567

protein ubiquitination

0.36

GO:0005515

protein binding

0.84	GO:0080008	Cul4-RING E3 ubiquitin ligase complex
0.75	GO:0005813	centrosome
0.48	GO:0005737	cytoplasm

tr|Q6P812|Q6P812_XENTR
SEC13 homolog, nuclear pore and COPII coat complex component
Search

SEC13

0.97	SEC13 homolog, nuclear pore and COPII coat complex component

0.84	GO:1904263	positive regulation of TORC1 signaling
0.83	GO:0090114	COPII-coated vesicle budding
0.65	GO:0015031	protein transport
0.55	GO:0035459	cargo loading into vesicle
0.53	GO:0051668	localization within membrane
0.46	GO:0070278	extracellular matrix constituent secretion
0.45	GO:0010842	retina layer formation
0.44	GO:0042462	eye photoreceptor cell development
0.44	GO:0001889	liver development
0.43	GO:0051216	cartilage development

0.62	GO:0005198	structural molecule activity
0.49	GO:0042802	identical protein binding
0.33	GO:0008270	zinc ion binding

0.80	GO:0030127	COPII vesicle coat
0.74	GO:0000139	Golgi membrane
0.54	GO:0061700	GATOR2 complex
0.53	GO:0031080	nuclear pore outer ring
0.52	GO:0005765	lysosomal membrane
0.51	GO:0000776	kinetochore
0.47	GO:0005654	nucleoplasm
0.44	GO:0070971	endoplasmic reticulum exit site
0.37	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0070062	extracellular exosome

sp|Q6P816|YKT6_XENTR
Synaptobrevin homolog YKT6
Search

YKT6

0.92	Synaptobrevin like protein YKT6

0.67	GO:0016192	vesicle-mediated transport
0.51	GO:0051650	establishment of vesicle localization
0.50	GO:0016482	cytosolic transport
0.50	GO:0140056	organelle localization by membrane tethering
0.49	GO:0016197	endosomal transport
0.48	GO:0032940	secretion by cell
0.47	GO:0061025	membrane fusion
0.46	GO:0048284	organelle fusion
0.46	GO:0016050	vesicle organization
0.38	GO:0015031	protein transport

0.53	GO:0005484	SNAP receptor activity
0.51	GO:0045296	cadherin binding
0.51	GO:0019706	protein-cysteine S-palmitoyltransferase activity
0.47	GO:0000149	SNARE binding
0.34	GO:0004683	calmodulin-dependent protein kinase activity
0.34	GO:0005516	calmodulin binding

0.48	GO:0031410	cytoplasmic vesicle
0.48	GO:0005794	Golgi apparatus
0.48	GO:0031201	SNARE complex
0.47	GO:0005829	cytosol
0.47	GO:0005783	endoplasmic reticulum
0.45	GO:0005887	integral component of plasma membrane
0.43	GO:0005739	mitochondrion
0.41	GO:0012506	vesicle membrane
0.41	GO:0097441	basal dendrite
0.40	GO:0097440	apical dendrite

0.51

EC:2.3.1.225

GO:0019706

tr|Q6P818|Q6P818_XENTR
Mitochondrial carrier 2
Search

MTCH2

0.62	Mitochondrial carrier like protein 2

0.51	GO:0070585	protein localization to mitochondrion
0.47	GO:0043065	positive regulation of apoptotic process
0.45	GO:0045444	fat cell differentiation
0.45	GO:0001889	liver development
0.44	GO:0048565	digestive tract development
0.41	GO:2001056	positive regulation of cysteine-type endopeptidase activity
0.41	GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.39	GO:0010917	negative regulation of mitochondrial membrane potential
0.39	GO:0035701	hematopoietic stem cell migration
0.39	GO:0061484	hematopoietic stem cell homeostasis

0.34	GO:0004181	metallocarboxypeptidase activity
0.33	GO:0008270	zinc ion binding

0.41	GO:0005739	mitochondrion
0.38	GO:0070062	extracellular exosome
0.37	GO:0031968	organelle outer membrane
0.37	GO:0019866	organelle inner membrane
0.35	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:3.4.17

GO:0004181

sp|Q6P819|RCD1_XENTR
Cell differentiation protein RCD1 homolog
Search

CNOT9

0.83	Cell differentiation protein RCD1

0.74	GO:0006402	mRNA catabolic process
0.57	GO:2000327	positive regulation of ligand-dependent nuclear receptor transcription coactivator activity
0.55	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway
0.52	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway
0.51	GO:0033138	positive regulation of peptidyl-serine phosphorylation
0.49	GO:0019221	cytokine-mediated signaling pathway
0.45	GO:0017148	negative regulation of translation
0.41	GO:0031047	gene silencing by RNA
0.37	GO:0007340	acrosome reaction
0.37	GO:0006351	transcription, DNA-templated

0.52	GO:0005154	epidermal growth factor receptor binding
0.48	GO:0019900	kinase binding
0.48	GO:0019904	protein domain specific binding
0.47	GO:0042803	protein homodimerization activity
0.37	GO:0004435	phosphatidylinositol phospholipase C activity
0.35	GO:0005509	calcium ion binding
0.34	GO:0004871	signal transducer activity
0.34	GO:0004108	citrate (Si)-synthase activity

0.82	GO:0030014	CCR4-NOT complex
0.53	GO:0000932	P-body
0.37	GO:0005634	nucleus
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.37	EC:3.1.4.11	GO:0004435
0.37	KEGG:R03435	GO:0004435

tr|Q6P822|Q6P822_XENTR
Uncharacterized protein
Search

CNPPD1

0.97	Cyclin Pas1/PHO80 domain containing 1

0.80

GO:0000079

regulation of cyclin-dependent protein serine/threonine kinase activity

0.78

GO:0019901

protein kinase binding

0.30

GO:0044425

membrane part

sp|Q6P823|H33_XENTR
Histone H3.3
Search

0.43	GO:0006334	nucleosome assembly
0.37	GO:0007140	male meiotic nuclear division
0.36	GO:0034724	DNA replication-independent nucleosome organization
0.36	GO:0030307	positive regulation of cell growth

0.74	GO:0046982	protein heterodimerization activity
0.55	GO:0003677	DNA binding
0.45	GO:0031491	nucleosome binding
0.39	GO:0098770	FBXO family protein binding
0.35	GO:0001067	regulatory region nucleic acid binding

0.75	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.37	GO:0005700	polytene chromosome
0.35	GO:0000781	chromosome, telomeric region
0.34	GO:0043233	organelle lumen
0.33	GO:0043234	protein complex

sp|Q6P824|GPD1L_XENTR
Glycerol-3-phosphate dehydrogenase 1-like protein
Search

GPD1L

0.68	Glycerol-3-phosphate dehydrogenase [NAD(+)]

0.78	GO:0046168	glycerol-3-phosphate catabolic process
0.60	GO:0005975	carbohydrate metabolic process
0.55	GO:0090038	negative regulation of protein kinase C signaling
0.55	GO:0060373	regulation of ventricular cardiac muscle cell membrane depolarization
0.54	GO:2000010	positive regulation of protein localization to cell surface
0.54	GO:0086005	ventricular cardiac muscle cell action potential
0.53	GO:0006734	NADH metabolic process
0.53	GO:0033137	negative regulation of peptidyl-serine phosphorylation
0.53	GO:0010765	positive regulation of sodium ion transport
0.53	GO:2000649	regulation of sodium ion transmembrane transporter activity

0.79	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity
0.75	GO:0042803	protein homodimerization activity
0.67	GO:0051287	NAD binding
0.53	GO:0017080	sodium channel regulator activity
0.52	GO:0044325	ion channel binding
0.36	GO:0004368	glycerol-3-phosphate dehydrogenase activity

0.75	GO:0009331	glycerol-3-phosphate dehydrogenase complex
0.40	GO:0005886	plasma membrane
0.37	GO:0070062	extracellular exosome
0.36	GO:0005829	cytosol
0.35	GO:0005739	mitochondrion
0.34	GO:0071565	nBAF complex
0.34	GO:0071564	npBAF complex
0.34	GO:0016514	SWI/SNF complex
0.30	GO:0031224	intrinsic component of membrane

0.79	EC:1.1.1.8 EC:1.1.1.94	GO:0004367
0.79	KEGG:R00842	GO:0004367

sp|Q6P825|TOM40_XENTR
Mitochondrial import receptor subunit TOM40 homolog
Search

TOMM40

0.86	Translocase of outer mitochondrial membrane 40 like

0.82	GO:0030150	protein import into mitochondrial matrix
0.35	GO:0006811	ion transport

0.74	GO:0008320	protein transmembrane transporter activity
0.39	GO:0070678	preprotein binding
0.38	GO:0015288	porin activity
0.38	GO:0030943	mitochondrion targeting sequence binding

0.78	GO:0005741	mitochondrial outer membrane
0.47	GO:0098798	mitochondrial protein complex
0.47	GO:0044455	mitochondrial membrane part
0.43	GO:0098796	membrane protein complex
0.38	GO:0005829	cytosol
0.38	GO:0031301	integral component of organelle membrane
0.37	GO:0005743	mitochondrial inner membrane

tr|Q6P827|Q6P827_XENTR
Nuclear receptor coactivator 5
Search

NCOA5

0.96	Nuclear receptor coactivator 5

0.74	GO:0046627	negative regulation of insulin receptor signaling pathway
0.69	GO:0042593	glucose homeostasis
0.37	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.36	GO:0006351	transcription, DNA-templated
0.36	GO:2001141	regulation of RNA biosynthetic process
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:0010468	regulation of gene expression
0.33	GO:0006468	protein phosphorylation

0.66	GO:0003682	chromatin binding
0.49	GO:0003723	RNA binding
0.36	GO:0005509	calcium ion binding
0.35	GO:0005515	protein binding
0.34	GO:0003677	DNA binding
0.33	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.63	GO:0015629	actin cytoskeleton
0.54	GO:0005634	nucleus
0.39	GO:0005615	extracellular space
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q6P828|LITAF_XENTR
Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog
Search

LITAF

0.90	Lipopolysaccharide induced TNF factor

0.84	GO:0042347	negative regulation of NF-kappaB import into nucleus
0.78	GO:0071222	cellular response to lipopolysaccharide
0.74	GO:0001817	regulation of cytokine production
0.72	GO:0045944	positive regulation of transcription by RNA polymerase II
0.41	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.37	GO:0007165	signal transduction

0.84	GO:0050699	WW domain binding
0.77	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.61	GO:0008270	zinc ion binding
0.37	GO:0004871	signal transducer activity

0.86	GO:0098560	cytoplasmic side of late endosome membrane
0.86	GO:0098559	cytoplasmic side of early endosome membrane
0.86	GO:0098574	cytoplasmic side of lysosomal membrane
0.73	GO:0009898	cytoplasmic side of plasma membrane
0.68	GO:0005794	Golgi apparatus
0.67	GO:0005654	nucleoplasm
0.66	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q6P829|NOSIP_XENTR
Nitric oxide synthase-interacting protein
Search

NOSIP

0.93	Nitric oxide synthase interacting protein (Fragment)

0.70	GO:0016567	protein ubiquitination
0.56	GO:0051001	negative regulation of nitric-oxide synthase activity
0.39	GO:0007275	multicellular organism development

0.74	GO:0061630	ubiquitin protein ligase activity
0.34	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.59	GO:0005634	nucleus
0.45	GO:0005737	cytoplasm
0.34	GO:0098588	bounding membrane of organelle
0.34	GO:0031984	organelle subcompartment
0.33	GO:0012505	endomembrane system
0.30	GO:0031224	intrinsic component of membrane

tr|Q6P831|Q6P831_XENTR
Sorting nexin 12
Search

SNX3

0.75	Sorting nexin-3

0.62	GO:2000642	negative regulation of early endosome to late endosome transport
0.57	GO:0042177	negative regulation of protein catabolic process
0.57	GO:0051224	negative regulation of protein transport
0.56	GO:0030100	regulation of endocytosis
0.56	GO:0022615	protein to membrane docking
0.55	GO:0046597	negative regulation of viral entry into host cell
0.55	GO:0016050	vesicle organization
0.53	GO:0010324	membrane invagination
0.51	GO:0030111	regulation of Wnt signaling pathway
0.50	GO:0010256	endomembrane system organization

0.77	GO:0035091	phosphatidylinositol binding
0.52	GO:0019903	protein phosphatase binding

0.55	GO:0005769	early endosome
0.55	GO:0032009	early phagosome
0.52	GO:0030904	retromer complex
0.51	GO:0030136	clathrin-coated vesicle
0.50	GO:0010008	endosome membrane
0.47	GO:0019898	extrinsic component of membrane
0.46	GO:0005829	cytosol
0.38	GO:0070062	extracellular exosome

sp|Q6P832|GATM_XENTR
Glycine amidinotransferase, mitochondrial
Search

GATM

0.88	LOW QUALITY PROTEIN: glycine amidinotransferase, mitochondrial

0.64	GO:0006601	creatine biosynthetic process
0.62	GO:0014889	muscle atrophy
0.57	GO:0007611	learning or memory
0.51	GO:0007275	multicellular organism development
0.35	GO:0042246	tissue regeneration
0.35	GO:0007584	response to nutrient
0.35	GO:0043434	response to peptide hormone
0.35	GO:0046689	response to mercury ion
0.34	GO:0006979	response to oxidative stress

0.84

GO:0015067

amidinotransferase activity

0.56	GO:0005758	mitochondrial intermembrane space
0.40	GO:0031966	mitochondrial membrane
0.40	GO:0019866	organelle inner membrane
0.37	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.84

EC:2.1.4

GO:0015067

sp|Q6P833|LSM12_XENTR
Protein LSM12 homolog
Search

0.45	GO:0070932	histone H3 deacetylation
0.45	GO:0040029	regulation of gene expression, epigenetic
0.41	GO:0006749	glutathione metabolic process
0.38	GO:0006351	transcription, DNA-templated
0.38	GO:1903506	regulation of nucleic acid-templated transcription
0.38	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.46	GO:0032041	NAD-dependent histone deacetylase activity (H3-K14 specific)
0.41	GO:0004364	glutathione transferase activity

0.39	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.46

EC:3.5.1.98

GO:0032041

tr|Q6P834|Q6P834_XENTR
Ras homolog enriched in brain like 1
Search

RHEBL1

0.50	Rheb small monomeric GTPase RhbA

0.63	GO:0071851	mitotic G1 cell cycle arrest in response to nitrogen starvation
0.62	GO:1905541	regulation of L-arginine import across plasma membrane
0.62	GO:1901042	positive regulation of L-arginine import
0.62	GO:1903961	positive regulation of anion transmembrane transport
0.61	GO:0015819	lysine transport
0.61	GO:0007165	signal transduction
0.59	GO:0015809	arginine transport
0.59	GO:1904064	positive regulation of cation transmembrane transport
0.57	GO:0042147	retrograde transport, endosome to Golgi
0.52	GO:0051092	positive regulation of NF-kappaB transcription factor activity

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0004828	serine-tRNA ligase activity
0.36	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.35	GO:0046872	metal ion binding
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0008144	drug binding

0.55	GO:0019897	extrinsic component of plasma membrane
0.51	GO:0005829	cytosol
0.36	GO:0012505	endomembrane system
0.35	GO:0035097	histone methyltransferase complex
0.35	GO:0005776	autophagosome
0.35	GO:0010494	cytoplasmic stress granule
0.34	GO:0031410	cytoplasmic vesicle
0.34	GO:0005615	extracellular space

0.37

EC:6.1.1.11

GO:0004828

tr|Q6P836|Q6P836_XENTR
SH3-domain GRB2-like 1
Search

SH3GL1

0.96	Kinase C and casein kinase II substrate protein 3

0.71	GO:0006897	endocytosis
0.57	GO:0072318	clathrin coat disassembly
0.55	GO:0036465	synaptic vesicle recycling
0.53	GO:0099003	vesicle-mediated transport in synapse
0.43	GO:0030100	regulation of endocytosis
0.41	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus
0.41	GO:0097484	dendrite extension
0.41	GO:1903421	regulation of synaptic vesicle recycling
0.40	GO:0098815	modulation of excitatory postsynaptic potential
0.37	GO:0099050	vesicle scission

0.52	GO:0045296	cadherin binding
0.51	GO:0042802	identical protein binding
0.41	GO:0031697	beta-1 adrenergic receptor binding
0.41	GO:0008022	protein C-terminus binding
0.40	GO:0044325	ion channel binding
0.39	GO:0019902	phosphatase binding
0.39	GO:0017124	SH3 domain binding
0.39	GO:0008289	lipid binding
0.38	GO:0051020	GTPase binding
0.35	GO:0019901	protein kinase binding

0.50	GO:0045202	synapse
0.49	GO:0005737	cytoplasm
0.41	GO:0097708	intracellular vesicle
0.40	GO:0002102	podosome
0.39	GO:0012505	endomembrane system
0.38	GO:0098805	whole membrane
0.38	GO:0030054	cell junction
0.38	GO:0098588	bounding membrane of organelle
0.37	GO:0042995	cell projection
0.35	GO:0070062	extracellular exosome

sp|Q6P839|FOXA4_XENTR
Forkhead box protein A4
Search

FOXA1

0.70	Fork head domain transcription factor

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.51	GO:1902691	respiratory basal cell differentiation
0.51	GO:0061144	alveolar secondary septum development
0.51	GO:0060741	prostate gland stromal morphogenesis
0.51	GO:0060738	epithelial-mesenchymal signaling involved in prostate gland development
0.50	GO:0060743	epithelial cell maturation involved in prostate gland development
0.50	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway
0.50	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development

0.74	GO:0019904	protein domain specific binding
0.71	GO:0008134	transcription factor binding
0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.47	GO:0044212	transcription regulatory region DNA binding
0.38	GO:0003690	double-stranded DNA binding
0.33	GO:0046872	metal ion binding

0.61	GO:0005634	nucleus
0.48	GO:0005902	microvillus
0.42	GO:0043233	organelle lumen
0.40	GO:0043232	intracellular non-membrane-bounded organelle
0.39	GO:0044446	intracellular organelle part

tr|Q6P844|Q6P844_XENTR
Frequenin homolog (Drosophila)
Search

NCS1

0.96	Neuronal calcium sensor 1

0.43	GO:1905949	negative regulation of calcium ion import across plasma membrane
0.43	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.42	GO:0048731	system development
0.41	GO:0120035	regulation of plasma membrane bounded cell projection organization
0.41	GO:0010446	response to alkaline pH
0.41	GO:0051960	regulation of nervous system development
0.41	GO:0060284	regulation of cell development
0.41	GO:0048522	positive regulation of cellular process
0.41	GO:0070588	calcium ion transmembrane transport
0.40	GO:0007635	chemosensory behavior

0.70	GO:0005509	calcium ion binding
0.44	GO:0098744	1-phosphatidylinositol 4-kinase activator activity
0.42	GO:0005245	voltage-gated calcium channel activity
0.38	GO:0019901	protein kinase binding
0.36	GO:0000287	magnesium ion binding
0.35	GO:0008427	calcium-dependent protein kinase inhibitor activity
0.35	GO:0016301	kinase activity

0.52	GO:0036477	somatodendritic compartment
0.50	GO:0030424	axon
0.48	GO:0120038	plasma membrane bounded cell projection part
0.43	GO:0005794	Golgi apparatus
0.42	GO:0005886	plasma membrane
0.41	GO:0014069	postsynaptic density
0.40	GO:0048471	perinuclear region of cytoplasm
0.40	GO:0044297	cell body
0.40	GO:0031045	dense core granule
0.39	GO:0030054	cell junction

tr|Q6P845|Q6P845_XENTR
Sorting nexin
Search

SNX6

0.75	Sorting nexin

0.69	GO:0006886	intracellular protein transport
0.45	GO:0016050	vesicle organization
0.42	GO:0006897	endocytosis
0.38	GO:0042147	retrograde transport, endosome to Golgi
0.38	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.37	GO:1903593	regulation of histamine secretion by mast cell
0.36	GO:0045892	negative regulation of transcription, DNA-templated
0.35	GO:0030042	actin filament depolymerization
0.35	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity
0.35	GO:0016241	regulation of macroautophagy

0.76	GO:0035091	phosphatidylinositol binding
0.47	GO:0034713	type I transforming growth factor beta receptor binding
0.40	GO:0034452	dynactin binding
0.37	GO:0042803	protein homodimerization activity
0.34	GO:0003779	actin binding
0.34	GO:0046982	protein heterodimerization activity
0.34	GO:0070003	threonine-type peptidase activity
0.33	GO:0004175	endopeptidase activity
0.32	GO:0046872	metal ion binding

0.48	GO:0005768	endosome
0.45	GO:0005764	lysosome
0.44	GO:0019898	extrinsic component of membrane
0.39	GO:0030904	retromer complex
0.37	GO:0044433	cytoplasmic vesicle part
0.37	GO:0098805	whole membrane
0.37	GO:0098588	bounding membrane of organelle
0.36	GO:0005829	cytosol
0.35	GO:0005634	nucleus
0.34	GO:0015629	actin cytoskeleton

tr|Q6P846|Q6P846_XENTR
Thymopoietin
Search

TMPO

0.97	Lamina associated polypeptide 2

0.41	GO:0031468	nuclear envelope reassembly
0.38	GO:1903047	mitotic cell cycle process
0.37	GO:1903506	regulation of nucleic acid-templated transcription
0.37	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.37	GO:0010468	regulation of gene expression
0.32	GO:0010469	regulation of receptor activity

0.50	GO:0003677	DNA binding
0.44	GO:0045296	cadherin binding
0.39	GO:0005521	lamin binding
0.38	GO:0003682	chromatin binding
0.35	GO:0042802	identical protein binding
0.33	GO:0005179	hormone activity

0.44	GO:0005635	nuclear envelope
0.42	GO:0005694	chromosome
0.38	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0031090	organelle membrane
0.34	GO:0098827	endoplasmic reticulum subcompartment
0.30	GO:0031224	intrinsic component of membrane

tr|Q6P847|Q6P847_XENTR
ATP synthase mitochondrial F1 complex assembly factor 2
Search

ATPAF2

0.93	ATP synthase mitochondrial F1 complex assembly factor 2

0.84

GO:0043461

proton-transporting ATP synthase complex assembly

0.33

GO:0005515

protein binding

0.52	GO:0016607	nuclear speck
0.47	GO:0005829	cytosol
0.35	GO:0005739	mitochondrion

sp|Q6P848|MARE1_XENTR
Microtubule-associated protein RP/EB family member 1
Search

MAPRE1

0.92	DNA methyltransferase 3 beta

0.80	GO:0070507	regulation of microtubule cytoskeleton organization
0.56	GO:0035372	protein localization to microtubule
0.52	GO:1903031	regulation of microtubule plus-end binding
0.52	GO:0032272	negative regulation of protein polymerization
0.52	GO:1904528	positive regulation of microtubule binding
0.52	GO:1902904	negative regulation of supramolecular fiber organization
0.52	GO:0051494	negative regulation of cytoskeleton organization
0.49	GO:0032273	positive regulation of protein polymerization
0.49	GO:1902905	positive regulation of supramolecular fiber organization
0.49	GO:0051495	positive regulation of cytoskeleton organization

0.84	GO:0051010	microtubule plus-end binding
0.50	GO:0045296	cadherin binding
0.49	GO:0019901	protein kinase binding
0.47	GO:0042802	identical protein binding
0.35	GO:0008022	protein C-terminus binding
0.34	GO:0008168	methyltransferase activity
0.34	GO:0003723	RNA binding
0.33	GO:0005509	calcium ion binding

0.72	GO:0005874	microtubule
0.56	GO:0030981	cortical microtubule cytoskeleton
0.50	GO:0005819	spindle
0.50	GO:0005815	microtubule organizing center
0.48	GO:0031253	cell projection membrane
0.45	GO:0005794	Golgi apparatus
0.33	GO:0005829	cytosol

0.34

EC:2.1.1

GO:0008168

tr|Q6P850|Q6P850_XENTR
Prohibitin
Search

PHB

0.84	Prohibitin transcript variant 2

0.55	GO:0045917	positive regulation of complement activation
0.54	GO:2000323	negative regulation of glucocorticoid receptor signaling pathway
0.54	GO:0050847	progesterone receptor signaling pathway
0.54	GO:0010944	negative regulation of transcription by competitive promoter binding
0.53	GO:0060766	negative regulation of androgen receptor signaling pathway
0.53	GO:0071354	cellular response to interleukin-6
0.52	GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway
0.52	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.51	GO:0042177	negative regulation of protein catabolic process
0.51	GO:0030308	negative regulation of cell growth

0.56	GO:0001850	complement component C3a binding
0.55	GO:0001851	complement component C3b binding
0.55	GO:0031871	proteinase activated receptor binding
0.51	GO:0042826	histone deacetylase binding
0.51	GO:0008022	protein C-terminus binding
0.48	GO:0044212	transcription regulatory region DNA binding
0.46	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding

0.50	GO:0043209	myelin sheath
0.49	GO:0005769	early endosome
0.49	GO:0009986	cell surface
0.45	GO:0005654	nucleoplasm
0.44	GO:0005887	integral component of plasma membrane
0.43	GO:0031966	mitochondrial membrane
0.43	GO:0019866	organelle inner membrane
0.36	GO:0070062	extracellular exosome
0.36	GO:0031312	extrinsic component of organelle membrane
0.35	GO:0031968	organelle outer membrane

tr|Q6P853|Q6P853_XENTR
Calcium activated nucleotidase 1
Search

CANT1

0.93	Soluble calcium-activated nucleotidase 1

0.57	GO:0030166	proteoglycan biosynthetic process
0.37	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.35	GO:0009191	ribonucleoside diphosphate catabolic process
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0007165	signal transduction

0.82	GO:0017110	nucleoside-diphosphatase activity
0.69	GO:0005509	calcium ion binding
0.50	GO:0042803	protein homodimerization activity
0.34	GO:0004871	signal transducer activity

0.38	GO:0032580	Golgi cisterna membrane
0.37	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0070062	extracellular exosome
0.36	GO:1904724	tertiary granule lumen
0.36	GO:0035580	specific granule lumen
0.36	GO:1904813	ficolin-1-rich granule lumen
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.82

EC:3.6.1.6

GO:0017110

sp|Q6P856|AP2M1_XENTR
AP-2 complex subunit mu
Search

AP2M1

0.87	AP-2 complex subunit mu-B

0.69	GO:0006886	intracellular protein transport
0.69	GO:0016192	vesicle-mediated transport
0.41	GO:0098657	import into cell
0.39	GO:0097494	regulation of vesicle size
0.39	GO:1900244	positive regulation of synaptic vesicle endocytosis
0.38	GO:1903077	negative regulation of protein localization to plasma membrane
0.38	GO:0002092	positive regulation of receptor internalization
0.38	GO:0016050	vesicle organization
0.38	GO:0036465	synaptic vesicle recycling
0.37	GO:0097480	establishment of synaptic vesicle localization

0.71	GO:0008289	lipid binding
0.51	GO:0097718	disordered domain specific binding
0.39	GO:0050750	low-density lipoprotein particle receptor binding
0.38	GO:0005048	signal sequence binding
0.37	GO:0044325	ion channel binding
0.35	GO:0035615	clathrin adaptor activity
0.35	GO:0004222	metalloendopeptidase activity
0.34	GO:0008270	zinc ion binding
0.32	GO:0005215	transporter activity

0.79	GO:0030131	clathrin adaptor complex
0.43	GO:0005905	clathrin-coated pit
0.41	GO:0005739	mitochondrion
0.41	GO:0005886	plasma membrane
0.39	GO:0030128	clathrin coat of endocytic vesicle
0.38	GO:0043195	terminal bouton
0.36	GO:0044421	extracellular region part
0.35	GO:0036020	endolysosome membrane
0.34	GO:0030141	secretory granule
0.33	GO:0005829	cytosol

0.35

EC:3.4.24

GO:0004222

sp|Q6P859|GPTC4_XENTR
G patch domain-containing protein 4
Search

GPATCH4

0.93	G patch domain-containing protein 4

0.35

GO:0002244

hematopoietic progenitor cell differentiation

0.51	GO:0003676	nucleic acid binding
0.39	GO:0000062	fatty-acyl-CoA binding
0.33	GO:0005198	structural molecule activity

0.35	GO:0005882	intermediate filament
0.30	GO:0031224	intrinsic component of membrane

sp|Q6P861|PP4C_XENTR
Serine/threonine-protein phosphatase 4 catalytic subunit
Search

PPP4C

0.48	Serine/threonine-protein phosphatase 4 catalytic subunit B

0.70	GO:0006470	protein dephosphorylation
0.55	GO:0010569	regulation of double-strand break repair via homologous recombination
0.38	GO:0048264	determination of ventral identity
0.36	GO:0038061	NIK/NF-kappaB signaling
0.36	GO:0030513	positive regulation of BMP signaling pathway
0.35	GO:0021952	central nervous system projection neuron axonogenesis
0.35	GO:0071347	cellular response to interleukin-1
0.34	GO:0001525	angiogenesis
0.34	GO:0007420	brain development
0.33	GO:0016310	phosphorylation

0.71	GO:0004721	phosphoprotein phosphatase activity
0.37	GO:0004704	NF-kappaB-inducing kinase activity
0.36	GO:0046872	metal ion binding
0.35	GO:0005515	protein binding
0.33	GO:0044877	macromolecular complex binding
0.33	GO:0004332	fructose-bisphosphate aldolase activity

0.53	GO:0030289	protein phosphatase 4 complex
0.46	GO:0005829	cytosol
0.44	GO:0005634	nucleus
0.41	GO:0005886	plasma membrane
0.41	GO:0005815	microtubule organizing center
0.33	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

0.71

EC:3.1.3.16

GO:0004721

sp|Q6P864|K1C18_XENTR
Keratin, type I cytoskeletal 18
Search

KRT18

0.91	Keratin, type I cytoskeletal 18-B

0.49	GO:0043000	Golgi to plasma membrane CFTR protein transport
0.46	GO:0097284	hepatocyte apoptotic process
0.46	GO:0045104	intermediate filament cytoskeleton organization
0.45	GO:0033209	tumor necrosis factor-mediated signaling pathway
0.44	GO:0097191	extrinsic apoptotic signaling pathway
0.44	GO:0043066	negative regulation of apoptotic process
0.43	GO:0098609	cell-cell adhesion
0.37	GO:0042074	cell migration involved in gastrulation
0.35	GO:0070268	cornification
0.34	GO:0097010	eukaryotic translation initiation factor 4F complex assembly

0.62	GO:0005198	structural molecule activity
0.47	GO:0098641	cadherin binding involved in cell-cell adhesion
0.46	GO:0097110	scaffold protein binding
0.34	GO:0003723	RNA binding

0.79	GO:0005882	intermediate filament
0.46	GO:0034451	centriolar satellite
0.45	GO:0005913	cell-cell adherens junction
0.42	GO:0005829	cytosol
0.37	GO:0071944	cell periphery
0.36	GO:0016363	nuclear matrix
0.36	GO:0005730	nucleolus
0.36	GO:0070062	extracellular exosome
0.34	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0036338	viral membrane

sp|Q6P870|PRRC1_XENTR
Protein PRRC1
Search

PRRC1

0.97	Proline rich coiled-coil 1

0.87	GO:0034199	activation of protein kinase A activity
0.85	GO:0001757	somite specification
0.84	GO:0010669	epithelial structure maintenance

0.84

GO:0034237

protein kinase A regulatory subunit binding

0.68	GO:0005794	Golgi apparatus
0.30	GO:0016020	membrane

tr|Q6P874|Q6P874_XENTR
RBBP8 N-terminal-like
Search

RBBP8NL

0.79	RBBP8 N-terminal like

0.85	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing
0.74	GO:0000724	double-strand break repair via homologous recombination
0.62	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.58	GO:0001835	blastocyst hatching
0.56	GO:0031572	G2 DNA damage checkpoint
0.54	GO:0000082	G1/S transition of mitotic cell cycle
0.52	GO:0000122	negative regulation of transcription by RNA polymerase II
0.50	GO:0006289	nucleotide-excision repair
0.41	GO:0051321	meiotic cell cycle
0.41	GO:0032355	response to estradiol

0.63	GO:0004519	endonuclease activity
0.57	GO:0001103	RNA polymerase II repressing transcription factor binding
0.56	GO:0001106	RNA polymerase II transcription corepressor activity
0.50	GO:0042802	identical protein binding
0.50	GO:0003684	damaged DNA binding
0.49	GO:0004536	deoxyribonuclease activity

0.59	GO:0005634	nucleus
0.54	GO:0017053	transcriptional repressor complex
0.48	GO:0031974	membrane-enclosed lumen
0.44	GO:0044446	intracellular organelle part
0.37	GO:0005615	extracellular space
0.37	GO:0005694	chromosome
0.30	GO:0031224	intrinsic component of membrane

sp|Q6P875|PUA2A_XENTR
Adenylosuccinate synthetase isozyme 2 A
Search

ADSS

0.45	Adenylosuccinate synthetase

0.73	GO:0044208	'de novo' AMP biosynthetic process
0.46	GO:0046040	IMP metabolic process
0.44	GO:0071257	cellular response to electrical stimulus
0.42	GO:0006531	aspartate metabolic process
0.39	GO:0014074	response to purine-containing compound
0.39	GO:0060359	response to ammonium ion
0.39	GO:0014850	response to muscle activity
0.38	GO:0035690	cellular response to drug
0.37	GO:0042594	response to starvation
0.36	GO:0006541	glutamine metabolic process

0.79	GO:0004019	adenylosuccinate synthase activity
0.66	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.59	GO:0000287	magnesium ion binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0003779	actin binding
0.37	GO:0042803	protein homodimerization activity
0.37	GO:0032403	protein complex binding
0.36	GO:0003924	GTPase activity

0.47	GO:0005737	cytoplasm
0.41	GO:0005886	plasma membrane
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.79	EC:6.3.4.4	GO:0004019
0.79	KEGG:R01135	GO:0004019

sp|Q6P877|ADRM1_XENTR
Proteasomal ubiquitin receptor ADRM1
Search

ADRM1

0.90	Adhesion regulating molecule 1

0.55	GO:0010950	positive regulation of endopeptidase activity
0.53	GO:0043248	proteasome assembly
0.51	GO:0006368	transcription elongation from RNA polymerase II promoter
0.43	GO:0006511	ubiquitin-dependent protein catabolic process
0.38	GO:0060399	positive regulation of growth hormone receptor signaling pathway
0.37	GO:0060009	Sertoli cell development
0.37	GO:0072520	seminiferous tubule development
0.37	GO:0033081	regulation of T cell differentiation in thymus
0.37	GO:0042699	follicle-stimulating hormone signaling pathway
0.37	GO:0060612	adipose tissue development

0.58	GO:0061133	endopeptidase activator activity
0.55	GO:0070628	proteasome binding
0.53	GO:0002020	protease binding
0.45	GO:0043130	ubiquitin binding

0.61	GO:0005634	nucleus
0.50	GO:1905369	endopeptidase complex
0.49	GO:0005737	cytoplasm
0.46	GO:0043233	organelle lumen
0.44	GO:0043234	protein complex
0.42	GO:0044446	intracellular organelle part
0.41	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q6P878|EIF3L_XENTR
Eukaryotic translation initiation factor 3 subunit L
Search

EIF3L

0.71	Eukaryotic translation initiation factor 3 subunit L

0.72	GO:0001731	formation of translation preinitiation complex
0.71	GO:0006446	regulation of translational initiation
0.54	GO:0075525	viral translational termination-reinitiation
0.38	GO:0032456	endocytic recycling
0.32	GO:0007165	signal transduction

0.71	GO:0003743	translation initiation factor activity
0.37	GO:0017137	Rab GTPase binding
0.34	GO:0046872	metal ion binding

0.77	GO:0005852	eukaryotic translation initiation factor 3 complex
0.71	GO:0016282	eukaryotic 43S preinitiation complex
0.71	GO:0033290	eukaryotic 48S preinitiation complex
0.51	GO:0001650	fibrillar center
0.46	GO:0005654	nucleoplasm
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

tr|Q6P879|Q6P879_XENTR
Ankyrin repeat and SOCS box-containing 12
Search

ASB12

0.97	Ankyrin repeat and SOCS box-containing protein 12

0.71	GO:0016567	protein ubiquitination
0.57	GO:0035556	intracellular signal transduction
0.36	GO:0043687	post-translational protein modification

0.57	GO:0061630	ubiquitin protein ligase activity
0.34	GO:0005515	protein binding

0.57	GO:0000151	ubiquitin ligase complex
0.35	GO:0005829	cytosol

sp|Q6P881|NSE1_XENTR
Non-structural maintenance of chromosomes element 1 homolog
Search

NSMCE1

0.95	NSE1 homolog, SMC5-SMC6 complex component

0.65	GO:0006281	DNA repair
0.62	GO:2001022	positive regulation of response to DNA damage stimulus
0.59	GO:0016567	protein ubiquitination
0.47	GO:0006310	DNA recombination
0.37	GO:0035556	intracellular signal transduction

0.60	GO:0004842	ubiquitin-protein transferase activity
0.52	GO:0046983	protein dimerization activity

0.81	GO:0030915	Smc5-Smc6 complex
0.53	GO:0005654	nucleoplasm

0.60

KEGG:R03876

GO:0004842

sp|Q6P882|ZB8AL_XENTR
Zinc finger and BTB domain-containing protein 8A.2
Search

ZBTB8A

0.97	Zinc finger and BTB domain-containing protein 8A

0.37	GO:0097659	nucleic acid-templated transcription
0.37	GO:1903506	regulation of nucleic acid-templated transcription
0.37	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.37	GO:0010468	regulation of gene expression
0.36	GO:0010467	gene expression
0.36	GO:0034645	cellular macromolecule biosynthetic process

0.51	GO:0003676	nucleic acid binding
0.36	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.38

GO:0005634

nucleus

sp|Q6P886|DBR1_XENTR
Lariat debranching enzyme
Search

DBR1

0.87	Lariat debranching enzyme A

0.70	GO:0006397	mRNA processing
0.53	GO:0000375	RNA splicing, via transesterification reactions
0.51	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.33	GO:0051028	mRNA transport

0.62	GO:0008419	RNA lariat debranching enzyme activity
0.34	GO:0003723	RNA binding
0.33	GO:0046872	metal ion binding

0.48	GO:0005654	nucleoplasm
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

tr|Q6P890|Q6P890_XENTR
B-cell receptor-associated protein 31
Search

BCAP31

0.96	B-cell receptor-associated protein 31

0.69	GO:0006886	intracellular protein transport
0.59	GO:0070973	protein localization to endoplasmic reticulum exit site
0.55	GO:1904154	positive regulation of retrograde protein transport, ER to cytosol
0.55	GO:1903071	positive regulation of ER-associated ubiquitin-dependent protein catabolic process
0.53	GO:0032471	negative regulation of endoplasmic reticulum calcium ion concentration
0.53	GO:0051561	positive regulation of mitochondrial calcium ion concentration
0.53	GO:0006888	ER to Golgi vesicle-mediated transport
0.53	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.52	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway
0.51	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process

0.54	GO:0042288	MHC class I protein binding
0.48	GO:0032403	protein complex binding
0.35	GO:0044325	ion channel binding
0.33	GO:0042393	histone binding
0.33	GO:0003682	chromatin binding

0.70	GO:0005783	endoplasmic reticulum
0.50	GO:0005811	lipid droplet
0.49	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.49	GO:0048471	perinuclear region of cytoplasm
0.48	GO:0031984	organelle subcompartment
0.47	GO:0044431	Golgi apparatus part
0.47	GO:0098588	bounding membrane of organelle
0.44	GO:0005887	integral component of plasma membrane
0.43	GO:0098796	membrane protein complex
0.42	GO:0005739	mitochondrion

tr|Q6P891|Q6P891_XENTR
Solute carrier family 7 (Cationic amino acid transporter, y+ system), member 8
Search

SLC7A8

0.65	Large neutral amino acids transporter small subunit 2

0.61	GO:0006865	amino acid transport
0.55	GO:0055085	transmembrane transport
0.52	GO:1901998	toxin transport
0.50	GO:0015695	organic cation transport
0.41	GO:0015893	drug transport
0.35	GO:0015837	amine transport
0.35	GO:0050900	leukocyte migration
0.34	GO:0055065	metal ion homeostasis
0.33	GO:0009636	response to toxic substance
0.33	GO:0006520	cellular amino acid metabolic process

0.57	GO:0022857	transmembrane transporter activity
0.39	GO:0042605	peptide antigen binding
0.33	GO:0005515	protein binding
0.32	GO:0003700	DNA binding transcription factor activity
0.32	GO:0004519	endonuclease activity
0.32	GO:0003676	nucleic acid binding

0.44	GO:0005887	integral component of plasma membrane
0.40	GO:0016323	basolateral plasma membrane
0.36	GO:0070062	extracellular exosome
0.34	GO:0005737	cytoplasm

tr|Q6P894|Q6P894_XENTR
Peptidylprolyl isomerase D (Cyclophilin D)
Search

PPID

0.74	Peptidyl-prolyl cis-trans isomerase D

0.72	GO:0000413	protein peptidyl-prolyl isomerization
0.68	GO:0006457	protein folding
0.58	GO:0071492	cellular response to UV-A
0.56	GO:0045070	positive regulation of viral genome replication
0.55	GO:0034389	lipid particle organization
0.53	GO:0050714	positive regulation of protein secretion
0.52	GO:0042981	regulation of apoptotic process
0.51	GO:0043068	positive regulation of programmed cell death
0.51	GO:0000122	negative regulation of transcription by RNA polymerase II
0.47	GO:0006461	protein complex assembly

0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.55	GO:0051879	Hsp90 protein binding
0.49	GO:0008134	transcription factor binding
0.40	GO:0051427	hormone receptor binding
0.40	GO:0030544	Hsp70 protein binding
0.38	GO:0016018	cyclosporin A binding
0.35	GO:0005528	FK506 binding
0.34	GO:0043022	ribosome binding
0.34	GO:0051082	unfolded protein binding
0.34	GO:0019899	enzyme binding

0.49	GO:0005730	nucleolus
0.47	GO:0005829	cytosol
0.37	GO:0005654	nucleoplasm
0.34	GO:0005739	mitochondrion
0.33	GO:0031970	organelle envelope lumen
0.32	GO:0000790	nuclear chromatin
0.32	GO:0032991	macromolecular complex
0.30	GO:0016020	membrane

0.72

EC:5.2.1.8

GO:0003755

tr|Q6P897|Q6P897_XENTR
Phosphatidic acid phosphatase type 2C
Search

0.94	Lipid phosphate phosphohydrolase 2

0.68	GO:0016311	dephosphorylation
0.44	GO:0030258	lipid modification
0.42	GO:0006644	phospholipid metabolic process
0.40	GO:0007165	signal transduction
0.35	GO:0030148	sphingolipid biosynthetic process
0.33	GO:0006464	cellular protein modification process

0.85	GO:0008195	phosphatidate phosphatase activity
0.49	GO:0042577	lipid phosphatase activity
0.35	GO:0042392	sphingosine-1-phosphate phosphatase activity
0.34	GO:0004721	phosphoprotein phosphatase activity
0.33	GO:0005515	protein binding
0.33	GO:0003677	DNA binding

0.42	GO:0005887	integral component of plasma membrane
0.34	GO:0005634	nucleus

0.85

EC:3.1.3.4

GO:0008195

tr|Q6P899|Q6P899_XENTR
Uncharacterized protein
Search

0.95	Leucine rich transmembrane and O-methyltransferase domain containing

0.56	GO:0007605	sensory perception of sound
0.51	GO:0032259	methylation
0.47	GO:0042424	catecholamine catabolic process
0.46	GO:0060117	auditory receptor cell development
0.39	GO:0016055	Wnt signaling pathway
0.38	GO:0090305	nucleic acid phosphodiester bond hydrolysis

0.66	GO:0016206	catechol O-methyltransferase activity
0.50	GO:0102084	L-dopa O-methyltransferase activity
0.50	GO:0102938	orcinol O-methyltransferase activity
0.40	GO:0008408	3'-5' exonuclease activity
0.35	GO:0003676	nucleic acid binding

0.44	GO:0005634	nucleus
0.41	GO:0005737	cytoplasm
0.37	GO:0098588	bounding membrane of organelle
0.37	GO:0005576	extracellular region
0.37	GO:0031984	organelle subcompartment
0.37	GO:0012505	endomembrane system
0.30	GO:0031224	intrinsic component of membrane

0.66

EC:2.1.1.6

GO:0016206

sp|Q6P8A1|SPC24_XENTR
Kinetochore protein spc24
Search

SPC24

0.75	Kinetochore protein spc24

0.60	GO:0051301	cell division
0.60	GO:0007049	cell cycle

0.86	GO:0031262	Ndc80 complex
0.71	GO:0000777	condensed chromosome kinetochore
0.61	GO:0005634	nucleus
0.52	GO:0031974	membrane-enclosed lumen

sp|Q6P8A3|FXI1E_XENTR
Forkhead box protein I1-ema
Search

FOXI1

0.92	Forkhead transcription factor i2

0.59	GO:0042472	inner ear morphogenesis
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression
0.54	GO:1902680	positive regulation of RNA biosynthetic process
0.54	GO:0006366	transcription by RNA polymerase II
0.49	GO:0030154	cell differentiation
0.45	GO:0008544	epidermis development
0.45	GO:0048890	lateral line ganglion development
0.44	GO:0060429	epithelium development

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0001012	RNA polymerase II regulatory region DNA binding
0.52	GO:0003690	double-stranded DNA binding
0.35	GO:0008301	DNA binding, bending

0.61	GO:0005634	nucleus
0.50	GO:0043233	organelle lumen
0.45	GO:0043232	intracellular non-membrane-bounded organelle
0.44	GO:0044446	intracellular organelle part

tr|Q6P8A4|Q6P8A4_XENTR
RGM domain family, member B
Search

RGMB

0.97	Repulsive guidance molecule family member b

0.81	GO:0030509	BMP signaling pathway
0.69	GO:0007155	cell adhesion
0.45	GO:0045893	positive regulation of transcription, DNA-templated
0.38	GO:0048681	negative regulation of axon regeneration
0.32	GO:0055114	oxidation-reduction process

0.51	GO:0015026	coreceptor activity
0.45	GO:0042802	identical protein binding
0.32	GO:0016491	oxidoreductase activity

0.78	GO:0046658	anchored component of plasma membrane
0.49	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.36	GO:0045121	membrane raft
0.30	GO:0016021	integral component of membrane

0.32

GO:0016491

sp|Q6P8A7|RBM24_XENTR
RNA-binding protein 24
Search

RBM24

0.91	RNA binding motif protein 24

0.63	GO:0051153	regulation of striated muscle cell differentiation
0.56	GO:0043488	regulation of mRNA stability
0.48	GO:0003228	atrial cardiac muscle tissue development
0.47	GO:0048702	embryonic neurocranium morphogenesis
0.46	GO:0001947	heart looping
0.46	GO:0001756	somitogenesis
0.45	GO:0007519	skeletal muscle tissue development
0.45	GO:0110020	regulation of actomyosin structure organization
0.44	GO:0072358	cardiovascular system development
0.44	GO:0043484	regulation of RNA splicing

0.58	GO:0003723	RNA binding
0.34	GO:0003779	actin binding
0.32	GO:0042802	identical protein binding

0.48	GO:0005829	cytosol
0.47	GO:0005654	nucleoplasm
0.33	GO:0014069	postsynaptic density

tr|Q6P8B2|Q6P8B2_XENTR
MID1 interacting protein 1 (Gastrulation specific G12-like (Zebrafish))
Search

0.96	Gastrulation-specific protein G12

0.84	GO:0051351	positive regulation of ligase activity
0.83	GO:0045723	positive regulation of fatty acid biosynthetic process
0.81	GO:0007026	negative regulation of microtubule depolymerization
0.72	GO:0051258	protein polymerization
0.41	GO:0006853	carnitine shuttle
0.40	GO:0010866	regulation of triglyceride biosynthetic process
0.38	GO:0006629	lipid metabolic process

0.77	GO:0008022	protein C-terminus binding
0.69	GO:0042802	identical protein binding
0.36	GO:0046983	protein dimerization activity

0.69	GO:0015630	microtubule cytoskeleton
0.65	GO:0005829	cytosol
0.60	GO:0005634	nucleus
0.49	GO:0099513	polymeric cytoskeletal fiber
0.36	GO:0043233	organelle lumen
0.30	GO:0031224	intrinsic component of membrane

sp|Q6P8B3|SPOP_XENTR
Speckle-type POZ protein
Search

SPOP

0.89	Speckle type BTB/POZ protein

0.85	GO:2000676	positive regulation of type B pancreatic cell apoptotic process
0.84	GO:1902237	positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
0.78	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.77	GO:0043433	negative regulation of DNA binding transcription factor activity
0.76	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.74	GO:0042593	glucose homeostasis
0.72	GO:0000122	negative regulation of transcription by RNA polymerase II
0.58	GO:0031397	negative regulation of protein ubiquitination
0.54	GO:0030162	regulation of proteolysis

0.77	GO:0001085	RNA polymerase II transcription factor binding
0.74	GO:0031625	ubiquitin protein ligase binding

0.83	GO:0031463	Cul3-RING ubiquitin ligase complex
0.74	GO:0016607	nuclear speck
0.59	GO:0019005	SCF ubiquitin ligase complex
0.40	GO:0005737	cytoplasm

tr|Q6P8B8|Q6P8B8_XENTR
Secreted frizzled-related protein 2
Search

SFRP2

0.97	Testicular tissue protein Li 170

0.74	GO:0016055	Wnt signaling pathway
0.69	GO:0007275	multicellular organism development
0.63	GO:0061185	negative regulation of dermatome development
0.62	GO:2000041	negative regulation of planar cell polarity pathway involved in axis elongation
0.62	GO:0030510	regulation of BMP signaling pathway
0.62	GO:0042662	negative regulation of mesodermal cell fate specification
0.61	GO:0071481	cellular response to X-ray
0.61	GO:2000035	regulation of stem cell division
0.60	GO:0035413	positive regulation of catenin import into nucleus
0.60	GO:0043508	negative regulation of JUN kinase activity

0.61	GO:0017147	Wnt-protein binding
0.60	GO:0061133	endopeptidase activator activity
0.53	GO:0048018	receptor ligand activity
0.50	GO:0042813	Wnt-activated receptor activity
0.45	GO:0004930	G-protein coupled receptor activity
0.37	GO:0001968	fibronectin binding
0.37	GO:0005178	integrin binding

0.65	GO:0005576	extracellular region
0.30	GO:0016020	membrane

tr|Q6P8C1|Q6P8C1_XENTR
Synaptosomal-associated protein, 29kDa
Search

SNAP29

0.96	Synaptosomal-associated protein 29

0.81	GO:0016240	autophagosome membrane docking
0.70	GO:0060271	cilium assembly
0.66	GO:0072114	pronephros morphogenesis
0.66	GO:0031629	synaptic vesicle fusion to presynaptic active zone membrane
0.65	GO:0016082	synaptic vesicle priming
0.64	GO:0048730	epidermis morphogenesis
0.43	GO:0015031	protein transport
0.40	GO:0043312	neutrophil degranulation
0.39	GO:0006903	vesicle targeting

0.61	GO:0019905	syntaxin binding
0.60	GO:0005484	SNAP receptor activity

0.81	GO:0020018	ciliary pocket membrane
0.75	GO:0031201	SNARE complex
0.70	GO:0005776	autophagosome
0.68	GO:0005813	centrosome
0.62	GO:0005654	nucleoplasm
0.61	GO:0005829	cytosol
0.59	GO:0098793	presynapse
0.47	GO:0005774	vacuolar membrane
0.46	GO:0000139	Golgi membrane
0.45	GO:0031410	cytoplasmic vesicle

sp|Q6P8C4|NHP2_XENTR
H/ACA ribonucleoprotein complex subunit 2-like protein
Search

NHP2

0.87	H/ACA ribonucleoprotein complex subunit 2

0.58	GO:1904874	positive regulation of telomerase RNA localization to Cajal body
0.52	GO:0031118	rRNA pseudouridine synthesis
0.50	GO:0031120	snRNA pseudouridine synthesis
0.48	GO:0000470	maturation of LSU-rRNA
0.47	GO:0000469	cleavage involved in rRNA processing
0.40	GO:0043043	peptide biosynthetic process
0.39	GO:0044267	cellular protein metabolic process
0.38	GO:0009059	macromolecule biosynthetic process
0.37	GO:0016074	snoRNA metabolic process
0.36	GO:0010833	telomere maintenance via telomere lengthening

0.60	GO:0034513	box H/ACA snoRNA binding
0.57	GO:0070034	telomerase RNA binding
0.38	GO:0034511	U3 snoRNA binding
0.37	GO:0003730	mRNA 3'-UTR binding
0.35	GO:0005515	protein binding

0.69	GO:0005730	nucleolus
0.59	GO:0019013	viral nucleocapsid
0.59	GO:0090661	box H/ACA telomerase RNP complex
0.47	GO:0022625	cytosolic large ribosomal subunit
0.46	GO:1902494	catalytic complex
0.41	GO:0015030	Cajal body
0.38	GO:0000784	nuclear chromosome, telomeric region

sp|Q6P8C8|ARL8A_XENTR
ADP-ribosylation factor-like protein 8A
Search

ARL8A

0.88	ADP ribosylation factor like GTPase 8A

0.38	GO:0007059	chromosome segregation
0.36	GO:0032418	lysosome localization
0.36	GO:0051301	cell division
0.36	GO:0007049	cell cycle
0.35	GO:0043312	neutrophil degranulation
0.34	GO:1903963	arachidonate transport
0.34	GO:0032309	icosanoid secretion
0.34	GO:0005975	carbohydrate metabolic process
0.33	GO:0016042	lipid catabolic process
0.33	GO:0035335	peptidyl-tyrosine dephosphorylation

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0043014	alpha-tubulin binding
0.37	GO:0048487	beta-tubulin binding
0.37	GO:0004415	hyalurononglucosaminidase activity
0.34	GO:0004623	phospholipase A2 activity
0.34	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters
0.33	GO:0005509	calcium ion binding

0.52	GO:0051233	spindle midzone
0.51	GO:0030496	midbody
0.41	GO:0005765	lysosomal membrane
0.38	GO:0031902	late endosome membrane
0.36	GO:0070062	extracellular exosome
0.35	GO:0101003	ficolin-1-rich granule membrane
0.35	GO:0005766	primary lysosome
0.32	GO:0005886	plasma membrane

0.37

EC:3.2.1.35

GO:0004415

tr|Q6P8D0|Q6P8D0_XENTR
60S acidic ribosomal protein P0
Search

RPLP0

0.67	60S acidic ribosomal protein P0

0.66	GO:0042254	ribosome biogenesis
0.47	GO:0071353	cellular response to interleukin-4
0.36	GO:1904401	cellular response to Thyroid stimulating hormone
0.35	GO:0010269	response to selenium ion
0.35	GO:0035722	interleukin-12-mediated signaling pathway
0.35	GO:1904628	cellular response to phorbol 13-acetate 12-myristate
0.35	GO:0007595	lactation
0.35	GO:0071320	cellular response to cAMP
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0043009	chordate embryonic development

0.43	GO:0003735	structural constituent of ribosome
0.34	GO:0042277	peptide binding
0.34	GO:0005515	protein binding
0.34	GO:0003723	RNA binding

0.60	GO:0005840	ribosome
0.49	GO:0036464	cytoplasmic ribonucleoprotein granule
0.46	GO:0044445	cytosolic part
0.46	GO:0005783	endoplasmic reticulum
0.45	GO:0030425	dendrite
0.43	GO:0005634	nucleus
0.41	GO:0044446	intracellular organelle part
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

sp|Q6P8D1|RSSA_XENTR
40S ribosomal protein SA
Search

RPSA

0.73	40S ribosomal protein SA

0.77	GO:0000028	ribosomal small subunit assembly
0.66	GO:0007155	cell adhesion
0.59	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.47	GO:0006407	rRNA export from nucleus
0.42	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.42	GO:0016072	rRNA metabolic process
0.37	GO:0030855	epithelial cell differentiation

0.85	GO:0005055	laminin receptor activity
0.80	GO:0043236	laminin binding
0.63	GO:0003735	structural constituent of ribosome
0.38	GO:0104005	hijacked molecular function
0.36	GO:0043022	ribosome binding
0.33	GO:0003723	RNA binding

0.74	GO:0022627	cytosolic small ribosomal subunit
0.58	GO:0005634	nucleus
0.53	GO:0005886	plasma membrane
0.46	GO:0030686	90S preribosome
0.37	GO:0005604	basement membrane
0.37	GO:0043025	neuronal cell body
0.36	GO:0070062	extracellular exosome
0.35	GO:0098556	cytoplasmic side of rough endoplasmic reticulum membrane
0.33	GO:0043233	organelle lumen

tr|Q6P8D6|Q6P8D6_XENTR
Vaccinia-related kinase 1
Search

VRK1

0.92	Serine/threonine-protein kinase VRK1

0.63	GO:0006468	protein phosphorylation
0.46	GO:0090166	Golgi disassembly
0.43	GO:0018209	peptidyl-serine modification
0.41	GO:0018210	peptidyl-threonine modification
0.39	GO:0008360	regulation of cell shape
0.39	GO:0016570	histone modification
0.39	GO:0051301	cell division
0.39	GO:0007049	cell cycle
0.37	GO:0051081	nuclear envelope disassembly
0.37	GO:0031468	nuclear envelope reassembly

0.69	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0031493	nucleosomal histone binding
0.42	GO:0035173	histone kinase activity
0.40	GO:0019901	protein kinase binding

0.43	GO:0005795	Golgi stack
0.40	GO:0005819	spindle
0.39	GO:0005730	nucleolus
0.38	GO:0005654	nucleoplasm
0.38	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.69

EC:2.7.11

GO:0004674

tr|Q6P8D7|Q6P8D7_XENTR
ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E
Search

ATP6V1E1

0.90	Vacuolar proton-ATPase E-subunit

0.76	GO:0015991	ATP hydrolysis coupled proton transport
0.45	GO:0060036	notochord cell vacuolation
0.45	GO:0033336	caudal fin development
0.44	GO:0031101	fin regeneration
0.43	GO:0060041	retina development in camera-type eye
0.37	GO:0090383	phagosome acidification
0.36	GO:0033572	transferrin transport
0.36	GO:0008286	insulin receptor signaling pathway
0.36	GO:0016241	regulation of macroautophagy

0.81	GO:0046961	proton-transporting ATPase activity, rotational mechanism
0.53	GO:0008553	proton-exporting ATPase activity, phosphorylative mechanism
0.47	GO:0051117	ATPase binding
0.45	GO:0008900	potassium:proton exchanging ATPase activity

0.72	GO:0033178	proton-transporting two-sector ATPase complex, catalytic domain
0.48	GO:0031410	cytoplasmic vesicle
0.47	GO:0005902	microvillus
0.47	GO:0016324	apical plasma membrane
0.46	GO:0012505	endomembrane system
0.46	GO:0097223	sperm part
0.43	GO:0005829	cytosol
0.39	GO:0005739	mitochondrion
0.37	GO:0005765	lysosomal membrane
0.36	GO:0070062	extracellular exosome

0.53

EC:3.6.3.6

GO:0008553

sp|Q6P8D9|UBC12_XENTR
NEDD8-conjugating enzyme Ubc12
Search

UBE2M

0.58	Ubiquitin-conjugating enzyme

0.52	GO:0045116	protein neddylation
0.46	GO:0016567	protein ubiquitination
0.39	GO:0043525	positive regulation of neuron apoptotic process
0.35	GO:0038061	NIK/NF-kappaB signaling
0.34	GO:0007179	transforming growth factor beta receptor signaling pathway
0.34	GO:0043687	post-translational protein modification

0.55	GO:0019788	NEDD8 transferase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0004842	ubiquitin-protein transferase activity
0.44	GO:0031625	ubiquitin protein ligase binding
0.43	GO:0061659	ubiquitin-like protein ligase activity
0.39	GO:0016874	ligase activity
0.32	GO:0003676	nucleic acid binding

0.36	GO:0070062	extracellular exosome
0.36	GO:0005737	cytoplasm
0.33	GO:0005654	nucleoplasm

0.39	EC:6	GO:0016874
0.48	KEGG:R03876	GO:0004842

tr|Q6P8E0|Q6P8E0_XENTR
Suppressor of cytokine signaling 3
Search

SOCS3

0.65	Suppressor of cytokine signaling 3

0.76	GO:0007259	JAK-STAT cascade
0.69	GO:0043066	negative regulation of apoptotic process
0.66	GO:0046426	negative regulation of JAK-STAT cascade
0.63	GO:0060330	regulation of response to interferon-gamma
0.55	GO:0001959	regulation of cytokine-mediated signaling pathway
0.53	GO:0016567	protein ubiquitination
0.49	GO:0046627	negative regulation of insulin receptor signaling pathway
0.47	GO:0006469	negative regulation of protein kinase activity
0.46	GO:0019221	cytokine-mediated signaling pathway
0.40	GO:0035162	embryonic hemopoiesis

0.47	GO:0004860	protein kinase inhibitor activity
0.36	GO:0004713	protein tyrosine kinase activity
0.34	GO:0004674	protein serine/threonine kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0004871	signal transducer activity
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.44	GO:0005622	intracellular
0.41	GO:0030430	host cell cytoplasm
0.30	GO:0016020	membrane

0.36

EC:2.7.10

GO:0004713

tr|Q6P8E2|Q6P8E2_XENTR
Troponin C type 2 (Fast)
Search

TNNC2

0.94	Fast skeletal muscle troponin C

0.56	GO:0006941	striated muscle contraction
0.54	GO:0050881	musculoskeletal movement
0.47	GO:0006937	regulation of muscle contraction
0.45	GO:0014823	response to activity
0.42	GO:0060047	heart contraction
0.39	GO:0003231	cardiac ventricle development
0.36	GO:0014883	transition between fast and slow fiber
0.36	GO:1903115	regulation of actin filament-based movement
0.35	GO:0003229	ventricular cardiac muscle tissue development
0.35	GO:0055008	cardiac muscle tissue morphogenesis

0.70	GO:0005509	calcium ion binding
0.49	GO:0003779	actin binding
0.48	GO:0048306	calcium-dependent protein binding
0.44	GO:0032403	protein complex binding
0.38	GO:0031014	troponin T binding
0.36	GO:0031013	troponin I binding
0.34	GO:0042803	protein homodimerization activity
0.34	GO:0047617	acyl-CoA hydrolase activity

0.54	GO:0036379	myofilament
0.52	GO:0030017	sarcomere
0.49	GO:0015629	actin cytoskeleton
0.47	GO:0044430	cytoskeletal part
0.43	GO:0043234	protein complex
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:3.1.2 EC:3.1.2.20

GO:0047617

sp|Q6P8E9|NH2L1_XENTR
NHP2-like protein 1
Search

SNU13

0.96	Small nuclear ribonucleoprotein 13

0.67	GO:0042254	ribosome biogenesis
0.50	GO:0000492	box C/D snoRNP assembly
0.48	GO:0007338	single fertilization
0.45	GO:0008380	RNA splicing
0.43	GO:0006397	mRNA processing
0.42	GO:0016072	rRNA metabolic process
0.41	GO:0034470	ncRNA processing
0.40	GO:0043043	peptide biosynthetic process
0.39	GO:0044267	cellular protein metabolic process
0.38	GO:0009059	macromolecule biosynthetic process

0.59	GO:0003723	RNA binding
0.49	GO:0051117	ATPase binding
0.33	GO:0003735	structural constituent of ribosome
0.32	GO:0016787	hydrolase activity
0.32	GO:0046872	metal ion binding

0.73	GO:0005730	nucleolus
0.61	GO:0030529	intracellular ribonucleoprotein complex
0.45	GO:0120114	Sm-like protein family complex
0.44	GO:0044445	cytosolic part
0.40	GO:0043234	protein complex
0.33	GO:0005654	nucleoplasm
0.33	GO:0019013	viral nucleocapsid
0.32	GO:0005886	plasma membrane

0.32

GO:0016787

sp|Q6P8F3|MK_XENTR
Midkine
Search

MDK

0.97	Pleiotrophic factor-alpha-2

0.76	GO:0010469	regulation of receptor activity
0.53	GO:0030421	defecation
0.52	GO:0021681	cerebellar granular layer development
0.52	GO:0021542	dentate gyrus development
0.52	GO:0007614	short-term memory
0.52	GO:0001662	behavioral fear response
0.51	GO:0009611	response to wounding
0.50	GO:0021987	cerebral cortex development
0.50	GO:0043524	negative regulation of neuron apoptotic process
0.50	GO:0050795	regulation of behavior

0.78	GO:0008083	growth factor activity
0.53	GO:0008201	heparin binding
0.39	GO:0035374	chondroitin sulfate binding
0.39	GO:0043395	heparan sulfate proteoglycan binding
0.37	GO:0019901	protein kinase binding

0.42	GO:0005576	extracellular region
0.37	GO:0012505	endomembrane system
0.35	GO:0042995	cell projection
0.35	GO:0043231	intracellular membrane-bounded organelle
0.35	GO:0044444	cytoplasmic part
0.34	GO:0043234	protein complex
0.34	GO:0009986	cell surface

tr|Q6P8F4|Q6P8F4_XENTR
Uncharacterized protein
Search

RAB35

0.80	THO complex subunit 6 homolog isoform X3

0.50	GO:0016197	endosomal transport
0.49	GO:0048227	plasma membrane to endosome transport
0.49	GO:0036010	protein localization to endosome
0.46	GO:0000281	mitotic cytokinesis
0.45	GO:0031175	neuron projection development
0.45	GO:0019882	antigen processing and presentation
0.38	GO:1990090	cellular response to nerve growth factor stimulus
0.34	GO:0015031	protein transport
0.34	GO:0033674	positive regulation of kinase activity
0.34	GO:0045859	regulation of protein kinase activity

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.41	GO:0071532	ankyrin repeat binding
0.40	GO:0032794	GTPase activating protein binding
0.35	GO:0004767	sphingomyelin phosphodiesterase activity
0.34	GO:0019887	protein kinase regulator activity

0.48	GO:0031410	cytoplasmic vesicle
0.47	GO:0098805	whole membrane
0.47	GO:0045171	intercellular bridge
0.46	GO:0031253	cell projection membrane
0.46	GO:0012505	endomembrane system
0.44	GO:0098588	bounding membrane of organelle
0.40	GO:0005739	mitochondrion
0.40	GO:0044446	intracellular organelle part
0.37	GO:0031225	anchored component of membrane
0.37	GO:0098793	presynapse

0.35	EC:3.1.4.12	GO:0004767
0.35	KEGG:R02541	GO:0004767

tr|Q6P8F5|Q6P8F5_XENTR
Eukaryotic translation initiation factor 1B
Search

EIF1B

0.92	Eukaryotic translation initiation factor 1

0.72	GO:0006413	translational initiation
0.47	GO:0006446	regulation of translational initiation
0.45	GO:0009048	dosage compensation by inactivation of X chromosome
0.34	GO:0006886	intracellular protein transport

0.73	GO:0003743	translation initiation factor activity
0.35	GO:0017137	Rab GTPase binding
0.33	GO:0003735	structural constituent of ribosome
0.32	GO:0016787	hydrolase activity

0.41	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.32	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

0.32

GO:0016787

sp|Q6P8F8|TM38A_XENTR
Trimeric intracellular cation channel type A
Search

TMEM38A

0.96	Transmembrane protein 38A

0.62	GO:0015672	monovalent inorganic cation transport
0.61	GO:0098655	cation transmembrane transport
0.44	GO:0030001	metal ion transport
0.42	GO:0098660	inorganic ion transmembrane transport
0.30	GO:0009987	cellular process

0.74	GO:0005261	cation channel activity
0.47	GO:0015079	potassium ion transmembrane transporter activity
0.46	GO:0022839	ion gated channel activity
0.46	GO:0008381	mechanosensitive ion channel activity

0.30

GO:0031224

intrinsic component of membrane

tr|Q6P8F9|Q6P8F9_XENTR
Troponin I type 1 (Skeletal, slow)
Search

0.89	Troponin I cardiac muscle

0.54	GO:0060048	cardiac muscle contraction
0.52	GO:0001980	regulation of systemic arterial blood pressure by ischemic conditions
0.50	GO:0055010	ventricular cardiac muscle tissue morphogenesis
0.49	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling
0.49	GO:0003009	skeletal muscle contraction
0.48	GO:0001570	vasculogenesis
0.47	GO:0006874	cellular calcium ion homeostasis
0.47	GO:0032780	negative regulation of ATPase activity
0.40	GO:0014883	transition between fast and slow fiber
0.39	GO:0006940	regulation of smooth muscle contraction

0.51	GO:0031014	troponin T binding
0.50	GO:0030172	troponin C binding
0.50	GO:0019855	calcium channel inhibitor activity
0.48	GO:0048306	calcium-dependent protein binding
0.46	GO:0019901	protein kinase binding
0.46	GO:0003779	actin binding
0.45	GO:0019904	protein domain specific binding
0.45	GO:0032403	protein complex binding
0.35	GO:0046872	metal ion binding
0.33	GO:0016887	ATPase activity

0.84	GO:0005861	troponin complex
0.50	GO:0097512	cardiac myofibril
0.33	GO:0005829	cytosol
0.32	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0016887

sp|Q6P8G0|EIF3D_XENTR
Eukaryotic translation initiation factor 3 subunit D
Search

EIF3D

0.73	Eukaryotic translation initiation factor 3 subunit D

0.81	GO:0002191	cap-dependent translational initiation
0.72	GO:0001731	formation of translation preinitiation complex
0.71	GO:0006446	regulation of translational initiation
0.58	GO:0075525	viral translational termination-reinitiation
0.58	GO:1902416	positive regulation of mRNA binding
0.57	GO:0075522	IRES-dependent viral translational initiation
0.56	GO:0001732	formation of cytoplasmic translation initiation complex
0.51	GO:0045727	positive regulation of translation
0.34	GO:0043044	ATP-dependent chromatin remodeling
0.34	GO:0006414	translational elongation

0.81	GO:0098808	mRNA cap binding
0.72	GO:0003743	translation initiation factor activity
0.34	GO:0042393	histone binding
0.34	GO:0003746	translation elongation factor activity
0.33	GO:0008270	zinc ion binding
0.33	GO:0003700	DNA binding transcription factor activity
0.33	GO:0016887	ATPase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding

0.77	GO:0005852	eukaryotic translation initiation factor 3 complex
0.72	GO:0016282	eukaryotic 43S preinitiation complex
0.72	GO:0033290	eukaryotic 48S preinitiation complex
0.34	GO:0016514	SWI/SNF complex
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.33

GO:0016887

sp|Q6P8G1|ILF2_XENTR
Interleukin enhancer-binding factor 2 homolog
Search

ILF2

0.95	Interleukin enhancer-binding factor 2

0.71	GO:0006955	immune response
0.48	GO:0045893	positive regulation of transcription, DNA-templated
0.41	GO:0006351	transcription, DNA-templated
0.35	GO:0002446	neutrophil mediated immunity
0.35	GO:0043299	leukocyte degranulation
0.35	GO:0042119	neutrophil activation

0.57	GO:0003723	RNA binding
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0016740	transferase activity
0.40	GO:0003677	DNA binding
0.34	GO:0005515	protein binding

0.48	GO:0005730	nucleolus
0.44	GO:0005576	extracellular region
0.42	GO:0030529	intracellular ribonucleoprotein complex
0.36	GO:1904724	tertiary granule lumen
0.36	GO:0035580	specific granule lumen
0.36	GO:1904813	ficolin-1-rich granule lumen
0.30	GO:0031224	intrinsic component of membrane

0.50

EC:2

GO:0016740

sp|Q6P8G3|ACT3_XENTR
Actin, alpha sarcomeric/skeletal
Search

0.84	Actin alpha skeletal muscle

0.72	GO:0090131	mesenchyme migration
0.59	GO:0030240	skeletal muscle thin filament assembly
0.59	GO:0010628	positive regulation of gene expression
0.55	GO:0014706	striated muscle tissue development
0.55	GO:0007517	muscle organ development
0.51	GO:0033275	actin-myosin filament sliding
0.49	GO:0014904	myotube cell development
0.49	GO:0055006	cardiac cell development
0.49	GO:0048747	muscle fiber development
0.49	GO:0060047	heart contraction

0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0017022	myosin binding
0.40	GO:0016887	ATPase activity
0.35	GO:0031013	troponin I binding
0.35	GO:0031432	titin binding
0.35	GO:0048306	calcium-dependent protein binding
0.34	GO:0005523	tropomyosin binding
0.34	GO:0003785	actin monomer binding

0.68	GO:0030175	filopodium
0.66	GO:0030027	lamellipodium
0.65	GO:0044297	cell body
0.56	GO:0042641	actomyosin
0.55	GO:0005884	actin filament
0.54	GO:0030017	sarcomere
0.49	GO:0097517	contractile actin filament bundle
0.48	GO:0036379	myofilament
0.39	GO:0072562	blood microparticle
0.38	GO:0070062	extracellular exosome

0.40

GO:0016887

tr|Q6P8G7|Q6P8G7_XENTR
Tubulin alpha chain
Search

0.53	Tubulin alpha chain

0.71	GO:0007017	microtubule-based process
0.71	GO:0007010	cytoskeleton organization
0.37	GO:0021634	optic nerve formation
0.36	GO:0030705	cytoskeleton-dependent intracellular transport
0.35	GO:0043066	negative regulation of apoptotic process
0.35	GO:0097711	ciliary basal body-plasma membrane docking
0.35	GO:0000086	G2/M transition of mitotic cell cycle
0.34	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.34	GO:0051301	cell division

0.77	GO:0005200	structural constituent of cytoskeleton
0.67	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0019904	protein domain specific binding
0.34	GO:0046982	protein heterodimerization activity
0.32	GO:0046872	metal ion binding

0.73	GO:0005874	microtubule
0.48	GO:0005737	cytoplasm
0.43	GO:0043209	myelin sheath
0.43	GO:0035770	ribonucleoprotein granule
0.42	GO:0031982	vesicle
0.40	GO:0012505	endomembrane system
0.38	GO:0045121	membrane raft
0.37	GO:0043230	extracellular organelle
0.36	GO:0005615	extracellular space
0.35	GO:0005634	nucleus

sp|Q6PBC1|RL35_XENTR
60S ribosomal protein L35
Search

RPL35

0.78	Ribosomal protein L35

0.59	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.47	GO:0042273	ribosomal large subunit biogenesis
0.44	GO:0016072	rRNA metabolic process
0.41	GO:0030218	erythrocyte differentiation
0.40	GO:0043009	chordate embryonic development
0.39	GO:0051726	regulation of cell cycle
0.35	GO:0071493	cellular response to UV-B

0.62	GO:0003735	structural constituent of ribosome
0.47	GO:0003729	mRNA binding
0.34	GO:0043021	ribonucleoprotein complex binding
0.33	GO:0044212	transcription regulatory region DNA binding
0.32	GO:0003700	DNA binding transcription factor activity

0.61	GO:0005840	ribosome
0.46	GO:0044445	cytosolic part
0.40	GO:0044446	intracellular organelle part
0.34	GO:0005791	rough endoplasmic reticulum
0.34	GO:0098562	cytoplasmic side of membrane
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0005634	nucleus
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0043233	organelle lumen
0.30	GO:0031224	intrinsic component of membrane

sp|Q6PBC3|MIA40_XENTR
Mitochondrial intermembrane space import and assembly protein 40
Search

CHCHD4

0.80	Coiled-coil-helix-coiled-coil-helix domain containing 4

0.86	GO:0018171	peptidyl-cysteine oxidation
0.86	GO:0022417	protein maturation by protein folding
0.85	GO:0045041	protein import into mitochondrial intermembrane space
0.81	GO:0051084	'de novo' posttranslational protein folding

0.71

GO:0015035

protein disulfide oxidoreductase activity

0.78

GO:0005758

mitochondrial intermembrane space

sp|Q6PBC4|RS4_XENTR
40S ribosomal protein S4
Search

RPS4X

0.68	Ribosomal protein S4, X-linked X isoform variant (Fragment)

0.60	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.48	GO:0008284	positive regulation of cell proliferation
0.48	GO:0045727	positive regulation of translation
0.47	GO:0007275	multicellular organism development
0.39	GO:0060322	head development
0.37	GO:0045471	response to ethanol
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

0.64	GO:0003735	structural constituent of ribosome
0.63	GO:0019843	rRNA binding
0.33	GO:0005515	protein binding

0.61	GO:0005840	ribosome
0.50	GO:0005844	polysome
0.49	GO:0044445	cytosolic part
0.48	GO:0036464	cytoplasmic ribonucleoprotein granule
0.43	GO:0044446	intracellular organelle part
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.35	GO:0031012	extracellular matrix
0.33	GO:0043233	organelle lumen
0.33	GO:0005634	nucleus

tr|Q6PBC8|Q6PBC8_XENTR
Transmembrane protein 101
Search

TMEM101

0.78	Transmembrane domain-containing protein (Fragment)

0.39	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.35	GO:0007165	signal transduction

0.36

GO:0004871

signal transducer activity

0.30

GO:0044425

membrane part

sp|Q6PBC9|IER5L_XENTR
Immediate early response gene 5-like protein
Search

IER5L

0.95	Immediate early response 5 like

0.85	GO:1900036	positive regulation of cellular response to heat
0.74	GO:0034605	cellular response to heat
0.70	GO:0042127	regulation of cell proliferation
0.69	GO:0045944	positive regulation of transcription by RNA polymerase II
0.39	GO:0006351	transcription, DNA-templated

0.68

GO:0042802

identical protein binding

0.74	GO:0000159	protein phosphatase type 2A complex
0.57	GO:0005634	nucleus
0.46	GO:0005737	cytoplasm

sp|Q6PBD1|SELT_XENTR
Selenoprotein T
Search

SELENOT

0.96	Selenoprotein T

0.60	GO:0035773	insulin secretion involved in cellular response to glucose stimulus
0.56	GO:0031016	pancreas development
0.49	GO:0045454	cell redox homeostasis
0.44	GO:0060124	positive regulation of growth hormone secretion
0.42	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.40	GO:0098869	cellular oxidant detoxification
0.36	GO:0055114	oxidation-reduction process
0.35	GO:0001514	selenocysteine incorporation

0.43	GO:0004791	thioredoxin-disulfide reductase activity
0.35	GO:0008430	selenium binding
0.33	GO:0005201	extracellular matrix structural constituent

0.50	GO:0005783	endoplasmic reticulum
0.41	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.40	GO:0031984	organelle subcompartment
0.33	GO:0005604	basement membrane
0.33	GO:0005581	collagen trimer
0.30	GO:0016021	integral component of membrane

0.43	EC:1.8.1.9	GO:0004791
0.43	KEGG:R02016	GO:0004791

sp|Q6PBD4|HES4_XENTR
Transcription factor HES-4
Search

HES1

0.88	BHLH-WRPW transcription factor

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:2000026	regulation of multicellular organismal development
0.54	GO:0060284	regulation of cell development
0.53	GO:0051093	negative regulation of developmental process
0.53	GO:0051241	negative regulation of multicellular organismal process
0.53	GO:0007399	nervous system development
0.52	GO:0007219	Notch signaling pathway

0.68	GO:0046983	protein dimerization activity
0.55	GO:0003677	DNA binding
0.47	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.47	GO:0042826	histone deacetylase binding
0.45	GO:0051087	chaperone binding
0.45	GO:0001067	regulatory region nucleic acid binding
0.44	GO:0042802	identical protein binding
0.40	GO:0043425	bHLH transcription factor binding
0.36	GO:0001222	transcription corepressor binding
0.35	GO:0008432	JUN kinase binding

0.61	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part
0.33	GO:0005694	chromosome

0.35

EC:3.2.1.23

GO:0004565

sp|Q6PBD6|WDR61_XENTR
WD repeat-containing protein 61
Search

WDR61

0.92	WD repeat and SOCS box-containing protein 2

0.86	GO:2001162	positive regulation of histone H3-K79 methylation
0.85	GO:0051571	positive regulation of histone H3-K4 methylation
0.85	GO:0080182	histone H3-K4 trimethylation
0.83	GO:0045638	negative regulation of myeloid cell differentiation
0.79	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter
0.45	GO:0016055	Wnt signaling pathway
0.39	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
0.39	GO:0006351	transcription, DNA-templated
0.37	GO:0016567	protein ubiquitination
0.35	GO:0000470	maturation of LSU-rRNA

0.35	GO:0005515	protein binding
0.35	GO:0016905	myosin heavy chain kinase activity

0.85	GO:0055087	Ski complex
0.84	GO:0035327	transcriptionally active chromatin
0.80	GO:0016593	Cdc73/Paf1 complex
0.66	GO:0005829	cytosol
0.36	GO:0070545	PeBoW complex
0.35	GO:0030687	preribosome, large subunit precursor
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:2.7.11.7

GO:0016905

sp|Q6PBD7|ID2_XENTR
DNA-binding protein inhibitor ID-2
Search

ID2

0.97	Inhibitor of DNA binding 2, dominant negative helix-loop-helix protein, a

0.72	GO:0045892	negative regulation of transcription, DNA-templated
0.58	GO:0061031	endodermal digestive tract morphogenesis
0.57	GO:0048715	negative regulation of oligodendrocyte differentiation
0.57	GO:0045664	regulation of neuron differentiation
0.56	GO:0045777	positive regulation of blood pressure
0.56	GO:0048710	regulation of astrocyte differentiation
0.56	GO:0048557	embryonic digestive tract morphogenesis
0.56	GO:0045578	negative regulation of B cell differentiation
0.56	GO:0090398	cellular senescence
0.56	GO:2000178	negative regulation of neural precursor cell proliferation

0.68	GO:0046983	protein dimerization activity
0.54	GO:0044325	ion channel binding
0.46	GO:0003677	DNA binding
0.41	GO:0008134	transcription factor binding
0.33	GO:0140110	transcription regulator activity

0.61	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.43	GO:0043234	protein complex
0.34	GO:0000785	chromatin

tr|Q6PBD9|Q6PBD9_XENTR
Beta-synuclein
Search

SNCB

0.91	Gamma-synuclein

0.73	GO:0014059	regulation of dopamine secretion
0.63	GO:0042417	dopamine metabolic process
0.60	GO:0043524	negative regulation of neuron apoptotic process
0.59	GO:0050808	synapse organization
0.57	GO:0007268	chemical synaptic transmission
0.54	GO:0051945	negative regulation of catecholamine uptake involved in synaptic transmission
0.54	GO:0051621	regulation of norepinephrine uptake
0.54	GO:1903284	positive regulation of glutathione peroxidase activity
0.54	GO:1903285	positive regulation of hydrogen peroxide catabolic process
0.54	GO:1904715	negative regulation of chaperone-mediated autophagy

0.64	GO:1903136	cuprous ion binding
0.53	GO:0048156	tau protein binding
0.52	GO:0005509	calcium ion binding
0.52	GO:0050544	arachidonic acid binding
0.51	GO:0043014	alpha-tubulin binding
0.51	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.51	GO:0030544	Hsp70 protein binding
0.50	GO:0019894	kinesin binding
0.50	GO:0070840	dynein complex binding
0.50	GO:0051219	phosphoprotein binding

0.61	GO:0016234	inclusion body
0.57	GO:0045202	synapse
0.53	GO:0031092	platelet alpha granule membrane
0.50	GO:0030426	growth cone
0.49	GO:0043025	neuronal cell body
0.49	GO:0030424	axon
0.48	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0005615	extracellular space
0.47	GO:0005739	mitochondrion
0.47	GO:0005938	cell cortex

0.39

GO:0016491

sp|Q6PBE2|SPF27_XENTR
Pre-mRNA-splicing factor SPF27
Search

BCAS2

0.94	BCAS2, pre-mRNA processing factor

0.70

GO:0006397

mRNA processing

0.72	GO:0005662	DNA replication factor A complex
0.72	GO:0071007	U2-type catalytic step 2 spliceosome
0.67	GO:0016607	nuclear speck
0.65	GO:0005813	centrosome
0.57	GO:0071011	precatalytic spliceosome
0.57	GO:0000974	Prp19 complex

tr|Q6PBE4|Q6PBE4_XENTR
Claudin
Search

0.69

Claudin

0.41	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
0.41	GO:0061436	establishment of skin barrier
0.40	GO:0070830	bicellular tight junction assembly
0.40	GO:0070293	renal absorption
0.40	GO:0051291	protein heterooligomerization
0.39	GO:0001666	response to hypoxia
0.39	GO:0003382	epithelial cell morphogenesis
0.39	GO:0051260	protein homooligomerization
0.38	GO:1902476	chloride transmembrane transport
0.35	GO:0055113	epiboly involved in gastrulation with mouth forming second

0.62	GO:0005198	structural molecule activity
0.38	GO:0005254	chloride channel activity
0.38	GO:0042802	identical protein binding

0.81	GO:0005923	bicellular tight junction
0.56	GO:0005886	plasma membrane
0.35	GO:1990794	basolateral part of cell
0.34	GO:0045177	apical part of cell
0.34	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

sp|Q6PBE5|TMM47_XENTR
Transmembrane protein 47
Search

TMEM47

0.96	Transmembrane protein 47

0.33

GO:0005515

protein binding

0.48	GO:0030054	cell junction
0.41	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

tr|Q6PBE7|Q6PBE7_XENTR
L-lactate dehydrogenase
Search

LDHB

0.53	L-lactate dehydrogenase B chain

0.60	GO:0005975	carbohydrate metabolic process
0.57	GO:0019752	carboxylic acid metabolic process
0.53	GO:0055114	oxidation-reduction process
0.37	GO:0019674	NAD metabolic process
0.36	GO:1901615	organic hydroxy compound metabolic process
0.33	GO:0016053	organic acid biosynthetic process
0.32	GO:0006091	generation of precursor metabolites and energy
0.32	GO:0009059	macromolecule biosynthetic process
0.32	GO:0044260	cellular macromolecule metabolic process

0.81	GO:0004459	L-lactate dehydrogenase activity
0.48	GO:0042802	identical protein binding
0.37	GO:0019900	kinase binding
0.36	GO:0051287	NAD binding
0.34	GO:0005212	structural constituent of eye lens
0.34	GO:0004373	glycogen (starch) synthase activity

0.51	GO:0043209	myelin sheath
0.50	GO:0045121	membrane raft
0.48	GO:0005737	cytoplasm
0.40	GO:0043227	membrane-bounded organelle
0.39	GO:0043229	intracellular organelle
0.37	GO:0043230	extracellular organelle
0.36	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane

0.81

EC:1.1.1.27

GO:0004459

tr|Q6PBE9|Q6PBE9_XENTR
V-type proton ATPase proteolipid subunit
Search

ATP6V0C

0.61	V-type proton ATPase proteolipid subunit

0.76	GO:0015991	ATP hydrolysis coupled proton transport
0.50	GO:0030177	positive regulation of Wnt signaling pathway
0.50	GO:0007042	lysosomal lumen acidification
0.41	GO:0060036	notochord cell vacuolation
0.40	GO:0001878	response to yeast
0.40	GO:0060059	embryonic retina morphogenesis in camera-type eye
0.35	GO:0090383	phagosome acidification
0.35	GO:0033572	transferrin transport
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0008286	insulin receptor signaling pathway

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.49	GO:0031625	ubiquitin protein ligase binding
0.46	GO:0036442	proton-exporting ATPase activity
0.44	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
0.34	GO:0005245	voltage-gated calcium channel activity
0.34	GO:0015662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
0.34	GO:0008448	N-acetylglucosamine-6-phosphate deacetylase activity

0.78	GO:0033179	proton-transporting V-type ATPase, V0 domain
0.76	GO:0005774	vacuolar membrane
0.36	GO:0005925	focal adhesion
0.36	GO:0031982	vesicle
0.36	GO:0043230	extracellular organelle
0.35	GO:0005764	lysosome
0.35	GO:0012505	endomembrane system
0.35	GO:0005615	extracellular space
0.34	GO:0048786	presynaptic active zone
0.32	GO:0005886	plasma membrane

0.34

EC:3.5.1.25

GO:0008448

sp|Q6PBF0|RL8_XENTR
60S ribosomal protein L8
Search

RPL8

0.80	Ribosomal protein L8

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.37	GO:1990090	cellular response to nerve growth factor stimulus
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.33	GO:0016072	rRNA metabolic process
0.33	GO:0042254	ribosome biogenesis

0.64	GO:0003735	structural constituent of ribosome
0.54	GO:0003723	RNA binding
0.33	GO:0005515	protein binding
0.32	GO:0016787	hydrolase activity

0.63	GO:0015934	large ribosomal subunit
0.52	GO:0022626	cytosolic ribosome
0.51	GO:0042788	polysomal ribosome
0.36	GO:0005925	focal adhesion
0.30	GO:0016020	membrane

0.32