Queries 8001 to 9000

GO:0004721

sp|Q08211|DHX9_HUMAN
ATP-dependent RNA helicase A
Search

DHX9

0.96	DEAH (Asp-Glu-Ala-His) box polypeptide 9

0.75	GO:1904973	positive regulation of viral translation
0.74	GO:1905698	positive regulation of polysome binding
0.73	GO:0039695	DNA-templated viral transcription
0.72	GO:2000373	positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity
0.72	GO:0035549	positive regulation of interferon-beta secretion
0.72	GO:0070934	CRD-mediated mRNA stabilization
0.72	GO:0046833	positive regulation of RNA export from nucleus
0.72	GO:1903608	protein localization to cytoplasmic stress granule
0.71	GO:1904469	positive regulation of tumor necrosis factor secretion
0.71	GO:1902741	positive regulation of interferon-alpha secretion

0.75	GO:0033681	ATP-dependent 3'-5' DNA/RNA helicase activity
0.75	GO:1905172	RISC complex binding
0.74	GO:1905538	polysome binding
0.73	GO:0001069	regulatory region RNA binding
0.72	GO:0045142	triplex DNA binding
0.71	GO:1990825	sequence-specific mRNA binding
0.71	GO:0061676	importin-alpha family protein binding
0.70	GO:0035613	RNA stem-loop binding
0.70	GO:1990518	single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity
0.70	GO:0035197	siRNA binding

0.72	GO:0005726	perichromatin fibrils
0.72	GO:0097165	nuclear stress granule
0.71	GO:0070937	CRD-mediated mRNA stability complex
0.70	GO:0070578	RISC-loading complex
0.69	GO:0035068	micro-ribonucleoprotein complex
0.67	GO:0042788	polysomal ribosome
0.63	GO:0036464	cytoplasmic ribonucleoprotein granule
0.62	GO:0005813	centrosome
0.62	GO:0016604	nuclear body
0.59	GO:0015629	actin cytoskeleton

0.60

EC:3.6.1.19

GO:0047429

sp|Q08257|QOR_HUMAN
Quinone oxidoreductase
Search

CRYZ

0.48	Quinone oxidoreductase

0.53	GO:0051289	protein homotetramerization
0.53	GO:0055114	oxidation-reduction process
0.51	GO:0042178	xenobiotic catabolic process
0.35	GO:0007601	visual perception

0.62	GO:0008270	zinc ion binding
0.54	GO:0003960	NADPH:quinone reductase activity
0.54	GO:0003730	mRNA 3'-UTR binding
0.52	GO:0070402	NADPH binding
0.44	GO:0070404	NADH binding
0.35	GO:0005212	structural constituent of eye lens
0.33	GO:0005515	protein binding
0.32	GO:0003677	DNA binding

0.47	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.54

EC:1.6.5.5

GO:0003960

sp|Q08289|CACB2_HUMAN
Voltage-dependent L-type calcium channel subunit beta-2
Search

CACNB2

0.92	L-type calcium channel beta subunit

0.76	GO:0070588	calcium ion transmembrane transport
0.58	GO:0098912	membrane depolarization during atrial cardiac muscle cell action potential
0.57	GO:0086045	membrane depolarization during AV node cell action potential
0.55	GO:0086091	regulation of heart rate by cardiac conduction
0.54	GO:0051924	regulation of calcium ion transport
0.53	GO:0070509	calcium ion import
0.52	GO:0043270	positive regulation of ion transport
0.50	GO:0007268	chemical synaptic transmission
0.50	GO:0007601	visual perception
0.47	GO:0007528	neuromuscular junction development

0.81	GO:0005245	voltage-gated calcium channel activity
0.49	GO:0051015	actin filament binding
0.35	GO:0005246	calcium channel regulator activity
0.35	GO:0051219	phosphoprotein binding
0.34	GO:0019901	protein kinase binding
0.34	GO:0019904	protein domain specific binding
0.34	GO:0042802	identical protein binding

0.80	GO:0005891	voltage-gated calcium channel complex
0.55	GO:0030315	T-tubule
0.34	GO:0005887	integral component of plasma membrane

sp|Q08334|I10R2_HUMAN
Interleukin-10 receptor subunit beta
Search

IL10RB

0.96	LOW QUALITY PROTEIN: interleukin-10 receptor subunit beta

0.50	GO:0007596	blood coagulation
0.49	GO:0019221	cytokine-mediated signaling pathway
0.38	GO:0051607	defense response to virus
0.37	GO:0006954	inflammatory response
0.36	GO:0006955	immune response

0.54	GO:0004920	interleukin-10 receptor activity
0.36	GO:0005515	protein binding

0.40	GO:0005886	plasma membrane
0.39	GO:0070062	extracellular exosome
0.36	GO:0043235	receptor complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q08345|DDR1_HUMAN
Epithelial discoidin domain-containing receptor 1
Search

DDR1

0.61	Tyrosine-protein kinase receptor

0.85	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.74	GO:0018108	peptidyl-tyrosine phosphorylation
0.67	GO:0061302	smooth muscle cell-matrix adhesion
0.66	GO:0014909	smooth muscle cell migration
0.65	GO:0010715	regulation of extracellular matrix disassembly
0.64	GO:0061377	mammary gland lobule development
0.63	GO:0060444	branching involved in mammary gland duct morphogenesis
0.63	GO:0090505	epiboly involved in wound healing
0.63	GO:0007566	embryo implantation
0.61	GO:1990138	neuron projection extension

0.86	GO:0038062	protein tyrosine kinase collagen receptor activity
0.60	GO:0005518	collagen binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0046872	metal ion binding
0.32	GO:0004003	ATP-dependent DNA helicase activity

0.67	GO:0005887	integral component of plasma membrane
0.57	GO:0043235	receptor complex
0.39	GO:0070062	extracellular exosome
0.36	GO:0016323	basolateral plasma membrane
0.32	GO:0000439	core TFIIH complex

sp|Q08357|S20A2_HUMAN
Sodium-dependent phosphate transporter 2
Search

SLC20A2

0.50	Sodium-dependent phosphate transporter 2

0.73	GO:0006817	phosphate ion transport
0.55	GO:0055085	transmembrane transport
0.44	GO:0006814	sodium ion transport
0.37	GO:0016032	viral process
0.36	GO:0030260	entry into host cell

0.75	GO:0005315	inorganic phosphate transmembrane transporter activity
0.50	GO:0015319	sodium:inorganic phosphate symporter activity
0.39	GO:0104005	hijacked molecular function
0.35	GO:0015321	sodium-dependent phosphate transmembrane transporter activity
0.34	GO:0008146	sulfotransferase activity
0.33	GO:0004872	receptor activity

0.42	GO:0005887	integral component of plasma membrane
0.36	GO:0070062	extracellular exosome

0.34

EC:2.8.2

GO:0008146

sp|Q08378|GOGA3_HUMAN
Golgin subfamily A member 3
Search

GOLGA3

0.96	Golgin subfamily A member 3-lik

0.79	GO:0007283	spermatogenesis
0.36	GO:0006891	intra-Golgi vesicle-mediated transport
0.34	GO:0030154	cell differentiation
0.34	GO:0007275	multicellular organism development

0.56	GO:0045296	cadherin binding
0.33	GO:0005215	transporter activity

0.86	GO:0090498	extrinsic component of Golgi membrane
0.56	GO:0017119	Golgi transport complex
0.52	GO:0005730	nucleolus
0.50	GO:0005654	nucleoplasm
0.50	GO:0005829	cytosol
0.38	GO:0032580	Golgi cisterna membrane
0.38	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment

sp|Q08379|GOGA2_HUMAN
Golgin subfamily A member 2
Search

GOLGA2

0.85	Golgin subfamily A member 2 isoform D

0.47	GO:0001966	thigmotaxis
0.45	GO:0090166	Golgi disassembly
0.45	GO:0060050	positive regulation of protein glycosylation
0.45	GO:0007519	skeletal muscle tissue development
0.45	GO:0007399	nervous system development
0.45	GO:0090161	Golgi ribbon formation
0.44	GO:0090306	spindle assembly involved in meiosis
0.43	GO:0060322	head development
0.43	GO:0008356	asymmetric cell division
0.43	GO:0051289	protein homotetramerization

0.45	GO:0061676	importin-alpha family protein binding
0.43	GO:0019905	syntaxin binding
0.42	GO:0045296	cadherin binding
0.42	GO:0019901	protein kinase binding
0.41	GO:0008017	microtubule binding
0.36	GO:0032403	protein complex binding
0.34	GO:0009982	pseudouridine synthase activity
0.33	GO:0003723	RNA binding

0.71	GO:0005794	Golgi apparatus
0.51	GO:0005801	cis-Golgi network
0.42	GO:0072686	mitotic spindle
0.42	GO:0030134	COPII-coated ER to Golgi transport vesicle
0.42	GO:0000922	spindle pole
0.40	GO:0005874	microtubule
0.40	GO:0098588	bounding membrane of organelle
0.39	GO:0031984	organelle subcompartment
0.38	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.37	GO:0043025	neuronal cell body

0.34

EC:5.4.99.12

GO:0009982

sp|Q08380|LG3BP_HUMAN
Galectin-3-binding protein
Search

LGALS3BP

0.94	galectin-3-binding protein precursor

0.72	GO:0006898	receptor-mediated endocytosis
0.43	GO:0007155	cell adhesion
0.39	GO:0006968	cellular defense response
0.39	GO:0002576	platelet degranulation
0.36	GO:0006334	nucleosome assembly
0.35	GO:0007165	signal transduction
0.35	GO:0006508	proteolysis
0.33	GO:0051604	protein maturation
0.32	GO:0006955	immune response

0.81	GO:0005044	scavenger receptor activity
0.37	GO:0017110	nucleoside-diphosphatase activity
0.37	GO:0005515	protein binding
0.36	GO:0004252	serine-type endopeptidase activity
0.35	GO:0005509	calcium ion binding
0.33	GO:0004930	G-protein coupled receptor activity
0.33	GO:0030246	carbohydrate binding
0.32	GO:0001871	pattern binding

0.57	GO:0031012	extracellular matrix
0.56	GO:0005615	extracellular space
0.40	GO:0031089	platelet dense granule lumen
0.40	GO:1903561	extracellular vesicle
0.34	GO:0043083	synaptic cleft
0.34	GO:0043195	terminal bouton
0.34	GO:0005634	nucleus
0.34	GO:0030425	dendrite
0.33	GO:0005581	collagen trimer
0.32	GO:0005886	plasma membrane

0.37

EC:3.6.1.6

GO:0017110

sp|Q08397|LOXL1_HUMAN
Lysyl oxidase homolog 1
Search

LOXL1

0.87	Lysyl oxidase like protein 1

0.53	GO:0055114	oxidation-reduction process
0.46	GO:0030903	notochord development
0.39	GO:0035904	aorta development
0.39	GO:0018277	protein deamination
0.38	GO:0030198	extracellular matrix organization
0.37	GO:0032496	response to lipopolysaccharide
0.36	GO:0051216	cartilage development
0.36	GO:0007517	muscle organ development
0.35	GO:0022008	neurogenesis
0.35	GO:0030324	lung development

0.77	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor
0.72	GO:0005507	copper ion binding
0.33	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0005515	protein binding

0.52	GO:0031012	extracellular matrix
0.38	GO:0005615	extracellular space
0.37	GO:0001669	acrosomal vesicle
0.35	GO:0005581	collagen trimer
0.32	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.77

EC:1.4.3

GO:0016641

sp|Q08426|ECHP_HUMAN
Peroxisomal bifunctional enzyme
Search

EHHADH

0.96	Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase

0.69	GO:0006631	fatty acid metabolic process
0.67	GO:0034440	lipid oxidation
0.65	GO:0044242	cellular lipid catabolic process
0.63	GO:0072329	monocarboxylic acid catabolic process
0.62	GO:0006475	internal protein amino acid acetylation

0.76	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity
0.59	GO:0005102	receptor binding
0.58	GO:0019899	enzyme binding
0.42	GO:0070403	NAD+ binding
0.38	GO:0016853	isomerase activity
0.35	GO:0016829	lyase activity

0.63	GO:0042579	microbody
0.50	GO:0005739	mitochondrion

0.76

EC:1.1.1.35

GO:0003857

sp|Q08431|MFGM_HUMAN
Lactadherin
Search

MFGE8

0.81	Milk fat globule-EGF factor 8 protein b

0.71	GO:0043277	apoptotic cell clearance
0.71	GO:0006910	phagocytosis, recognition
0.71	GO:0050766	positive regulation of phagocytosis
0.70	GO:0006911	phagocytosis, engulfment

0.71	GO:0008429	phosphatidylethanolamine binding
0.71	GO:0001786	phosphatidylserine binding
0.69	GO:0005178	integrin binding
0.56	GO:0005509	calcium ion binding

0.67	GO:0009897	external side of plasma membrane
0.64	GO:0031012	extracellular matrix
0.63	GO:0019897	extrinsic component of plasma membrane
0.61	GO:0005615	extracellular space

sp|Q08462|ADCY2_HUMAN
Adenylate cyclase type 2
Search

ADCY2

0.82	Adenylate cyclase type 2

0.79	GO:0006171	cAMP biosynthetic process
0.62	GO:0035556	intracellular signal transduction
0.47	GO:0006182	cGMP biosynthetic process
0.40	GO:1904321	response to forskolin
0.39	GO:1901655	cellular response to ketone
0.38	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.38	GO:0035690	cellular response to drug
0.38	GO:0007190	activation of adenylate cyclase activity
0.38	GO:0071396	cellular response to lipid
0.38	GO:0071407	cellular response to organic cyclic compound

0.79	GO:0004016	adenylate cyclase activity
0.52	GO:1901265	nucleoside phosphate binding
0.51	GO:0036094	small molecule binding
0.49	GO:0097367	carbohydrate derivative binding
0.49	GO:0008144	drug binding
0.48	GO:0043168	anion binding
0.47	GO:0004383	guanylate cyclase activity
0.39	GO:0008179	adenylate cyclase binding
0.37	GO:0046982	protein heterodimerization activity
0.37	GO:0030145	manganese ion binding

0.55	GO:0005886	plasma membrane
0.49	GO:0008074	guanylate cyclase complex, soluble
0.38	GO:0030425	dendrite
0.37	GO:0045121	membrane raft
0.30	GO:0016021	integral component of membrane

0.79

EC:4.6.1.1

GO:0004016

sp|Q08477|CP4F3_HUMAN
Docosahexaenoic acid omega-hydroxylase CYP4F3
Search

0.89	Cytochrome P450 family 4 subfamily F member 3

0.57	GO:0036102	leukotriene B4 metabolic process
0.57	GO:0036100	leukotriene catabolic process
0.54	GO:0042758	long-chain fatty acid catabolic process
0.54	GO:0003095	pressure natriuresis
0.54	GO:0006775	fat-soluble vitamin metabolic process
0.53	GO:0055114	oxidation-reduction process
0.51	GO:0003091	renal water homeostasis
0.51	GO:0019373	epoxygenase P450 pathway
0.51	GO:0055078	sodium ion homeostasis
0.49	GO:0000038	very long-chain fatty acid metabolic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.67	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.46	GO:0005504	fatty acid binding
0.41	GO:0019825	oxygen binding
0.33	GO:0003676	nucleic acid binding

0.48	GO:0016324	apical plasma membrane
0.40	GO:0043231	intracellular membrane-bounded organelle
0.39	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.38	GO:0031984	organelle subcompartment
0.37	GO:0005737	cytoplasm
0.37	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

0.68

EC:1.14

GO:0016705

sp|Q08493|PDE4C_HUMAN
cAMP-specific 3',5'-cyclic phosphodiesterase 4C
Search

PDE4C

0.56	Phosphodiesterase

0.60	GO:0007165	signal transduction
0.41	GO:0006198	cAMP catabolic process
0.38	GO:0043949	regulation of cAMP-mediated signaling
0.38	GO:0010738	regulation of protein kinase A signaling
0.37	GO:0035690	cellular response to drug
0.36	GO:0007608	sensory perception of smell
0.35	GO:0046676	negative regulation of insulin secretion

0.79	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.54	GO:0046872	metal ion binding
0.37	GO:0030552	cAMP binding
0.35	GO:0003924	GTPase activity
0.35	GO:0032550	purine ribonucleoside binding
0.34	GO:0019001	guanyl nucleotide binding
0.34	GO:0005515	protein binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0008144	drug binding

0.48	GO:0005929	cilium
0.37	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0005829	cytosol
0.36	GO:0005615	extracellular space
0.35	GO:0005654	nucleoplasm
0.34	GO:0005886	plasma membrane
0.33	GO:0001726	ruffle
0.32	GO:0120038	plasma membrane bounded cell projection part
0.30	GO:0016021	integral component of membrane

0.79

GO:0004114

sp|Q08495|DEMA_HUMAN
Dematin
Search

DMTN

0.97	Putative actin-binding lim zn-finger protein limatin involved in axon guidance

0.69	GO:0007010	cytoskeleton organization
0.61	GO:0035585	calcium-mediated signaling using extracellular calcium source
0.61	GO:1901731	positive regulation of platelet aggregation
0.61	GO:0070560	protein secretion by platelet
0.60	GO:0090315	negative regulation of protein targeting to membrane
0.59	GO:2001046	positive regulation of integrin-mediated signaling pathway
0.59	GO:0010763	positive regulation of fibroblast migration
0.58	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading
0.58	GO:0051895	negative regulation of focal adhesion assembly
0.58	GO:0010591	regulation of lamellipodium assembly

0.72	GO:0003779	actin binding
0.57	GO:0030507	spectrin binding
0.56	GO:0043621	protein self-association
0.51	GO:0005102	receptor binding
0.32	GO:0046872	metal ion binding

0.61	GO:0031095	platelet dense tubular network membrane
0.60	GO:0014731	spectrin-associated cytoskeleton
0.55	GO:0005884	actin filament
0.55	GO:0014069	postsynaptic density
0.55	GO:0031253	cell projection membrane
0.54	GO:0030863	cortical cytoskeleton
0.53	GO:0048471	perinuclear region of cytoplasm
0.50	GO:0031410	cytoplasmic vesicle
0.49	GO:0005829	cytosol
0.38	GO:0012505	endomembrane system

sp|Q08499|PDE4D_HUMAN
cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Search

PDE4D

0.55	Phosphodiesterase

0.61	GO:0007165	signal transduction
0.54	GO:1901898	negative regulation of relaxation of cardiac muscle
0.53	GO:0071872	cellular response to epinephrine stimulus
0.52	GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
0.52	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity
0.52	GO:0045822	negative regulation of heart contraction
0.52	GO:0032754	positive regulation of interleukin-5 production
0.52	GO:0033137	negative regulation of peptidyl-serine phosphorylation
0.51	GO:0086004	regulation of cardiac muscle cell contraction
0.51	GO:0030593	neutrophil chemotaxis

0.80	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.54	GO:0046872	metal ion binding
0.51	GO:0051117	ATPase binding
0.51	GO:0044325	ion channel binding
0.50	GO:0097110	scaffold protein binding
0.50	GO:0030552	cAMP binding
0.39	GO:0008144	drug binding
0.38	GO:0031698	beta-2 adrenergic receptor binding
0.36	GO:0031625	ubiquitin protein ligase binding
0.35	GO:0017124	SH3 domain binding

0.49	GO:0034704	calcium channel complex
0.49	GO:0031965	nuclear membrane
0.48	GO:0005813	centrosome
0.45	GO:0005829	cytosol
0.42	GO:0044459	plasma membrane part
0.36	GO:0045177	apical part of cell
0.35	GO:0030016	myofibril
0.34	GO:0005794	Golgi apparatus

0.80

GO:0004114

sp|Q08554|DSC1_HUMAN
Desmocollin-1
Search

DSC1

0.95	Desmosomal glycoprotein 2/3

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.50	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication
0.49	GO:0098911	regulation of ventricular cardiac muscle cell action potential
0.49	GO:0086091	regulation of heart rate by cardiac conduction
0.45	GO:0009267	cellular response to starvation
0.38	GO:0070268	cornification
0.36	GO:0043312	neutrophil degranulation
0.35	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.35	GO:0001701	in utero embryonic development
0.35	GO:0050821	protein stabilization

0.70	GO:0005509	calcium ion binding
0.36	GO:0045295	gamma-catenin binding
0.35	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication

0.56	GO:0005886	plasma membrane
0.52	GO:0030057	desmosome
0.48	GO:0014704	intercalated disc
0.47	GO:0005913	cell-cell adherens junction
0.44	GO:0031982	vesicle
0.39	GO:0043230	extracellular organelle
0.38	GO:0044444	cytoplasmic part
0.38	GO:0005615	extracellular space
0.38	GO:0043229	intracellular organelle
0.35	GO:0005921	gap junction

sp|Q08623|HDHD1_HUMAN
Pseudouridine-5'-phosphatase
Search

PUDP

0.89	pseudouridine-5'-monophosphatase

0.43	GO:0016311	dephosphorylation
0.35	GO:0043097	pyrimidine nucleoside salvage
0.34	GO:0009117	nucleotide metabolic process
0.34	GO:0042060	wound healing

0.50	GO:0016787	hydrolase activity
0.34	GO:0046872	metal ion binding

0.37	GO:0070062	extracellular exosome
0.36	GO:0005737	cytoplasm

0.50

GO:0016787

sp|Q08629|TICN1_HUMAN
Testican-1
Search

SPOCK1

0.94	SPARC/osteonectin, cwcv and kazal like domains proteoglycan 1

0.60	GO:0007165	signal transduction
0.56	GO:0010812	negative regulation of cell-substrate adhesion
0.55	GO:0010977	negative regulation of neuron projection development
0.52	GO:0010951	negative regulation of endopeptidase activity
0.46	GO:0001764	neuron migration
0.46	GO:0021953	central nervous system neuron differentiation
0.40	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan
0.35	GO:0001558	regulation of cell growth
0.34	GO:0007155	cell adhesion
0.34	GO:2000146	negative regulation of cell motility

0.70	GO:0005509	calcium ion binding
0.57	GO:0008191	metalloendopeptidase inhibitor activity
0.54	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.38	GO:0005539	glycosaminoglycan binding
0.35	GO:0004867	serine-type endopeptidase inhibitor activity

0.75	GO:0005578	proteinaceous extracellular matrix
0.50	GO:0005615	extracellular space
0.48	GO:0033268	node of Ranvier
0.46	GO:0031594	neuromuscular junction
0.46	GO:0016528	sarcoplasm
0.35	GO:0014069	postsynaptic density

sp|Q08648|SG11B_HUMAN
Sperm-associated antigen 11B
Search

SPAG11B

0.97	Sperm-associated antigen 11 variant C

0.56	GO:0006952	defense response
0.53	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.51	GO:0051715	cytolysis in other organism
0.39	GO:0007283	spermatogenesis

0.66	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

sp|Q08708|CLM6_HUMAN
CMRF35-like molecule 6
Search

0.96	Polymeric immunoglobulin receptor 4

0.49	GO:0051134	negative regulation of NK T cell activation
0.49	GO:1902569	negative regulation of activation of Janus kinase activity
0.49	GO:0034125	negative regulation of MyD88-dependent toll-like receptor signaling pathway
0.49	GO:1902567	negative regulation of eosinophil activation
0.48	GO:2000417	negative regulation of eosinophil migration
0.48	GO:0060101	negative regulation of phagocytosis, engulfment
0.48	GO:1902564	negative regulation of neutrophil activation
0.48	GO:0050859	negative regulation of B cell receptor signaling pathway
0.48	GO:0043305	negative regulation of mast cell degranulation
0.47	GO:0032516	positive regulation of phosphoprotein phosphatase activity

0.46	GO:0008429	phosphatidylethanolamine binding
0.46	GO:0001786	phosphatidylserine binding
0.41	GO:0038023	signaling receptor activity
0.36	GO:0099600	transmembrane receptor activity
0.36	GO:0005515	protein binding

0.37	GO:0005886	plasma membrane
0.37	GO:0070062	extracellular exosome
0.37	GO:0101003	ficolin-1-rich granule membrane
0.36	GO:0070821	tertiary granule membrane
0.34	GO:0005769	early endosome
0.34	GO:0005764	lysosome
0.30	GO:0016021	integral component of membrane

sp|Q08722|CD47_HUMAN
Leukocyte surface antigen CD47
Search

CD47

0.96	Leukocyte surface antigen CD47

0.64	GO:0008228	opsonization
0.60	GO:0050766	positive regulation of phagocytosis
0.59	GO:0050729	positive regulation of inflammatory response
0.57	GO:0008284	positive regulation of cell proliferation
0.56	GO:0050870	positive regulation of T cell activation
0.55	GO:0009617	response to bacterium
0.47	GO:0007165	signal transduction
0.42	GO:0007155	cell adhesion
0.38	GO:0016477	cell migration
0.38	GO:0043312	neutrophil degranulation

0.65	GO:0070053	thrombospondin receptor activity
0.36	GO:0005515	protein binding

0.57	GO:0070062	extracellular exosome
0.49	GO:0005887	integral component of plasma membrane
0.39	GO:0035579	specific granule membrane
0.39	GO:0070821	tertiary granule membrane

sp|Q08752|PPID_HUMAN
Peptidyl-prolyl cis-trans isomerase D
Search

PPID

0.72	Peptidyl-prolyl cis-trans isomerase D

0.71	GO:0000413	protein peptidyl-prolyl isomerization
0.68	GO:0006457	protein folding
0.62	GO:0071492	cellular response to UV-A
0.59	GO:0045070	positive regulation of viral genome replication
0.59	GO:0034389	lipid particle organization
0.57	GO:0050714	positive regulation of protein secretion
0.55	GO:0043065	positive regulation of apoptotic process
0.54	GO:0000122	negative regulation of transcription by RNA polymerase II
0.50	GO:0006461	protein complex assembly
0.40	GO:0006915	apoptotic process

0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.59	GO:0051879	Hsp90 protein binding
0.52	GO:0008134	transcription factor binding
0.42	GO:0051427	hormone receptor binding
0.42	GO:0030544	Hsp70 protein binding
0.39	GO:0016018	cyclosporin A binding
0.36	GO:0005528	FK506 binding
0.35	GO:0019899	enzyme binding
0.34	GO:0043022	ribosome binding
0.34	GO:0051082	unfolded protein binding

0.52	GO:0005730	nucleolus
0.50	GO:0005829	cytosol
0.38	GO:0005654	nucleoplasm
0.33	GO:0005739	mitochondrion

0.72

GO:0003755

sp|Q08828|ADCY1_HUMAN
Adenylate cyclase type 1
Search

ADCY1

0.77	Adenylate cyclase type 1

0.74	GO:0006171	cAMP biosynthetic process
0.62	GO:0035556	intracellular signal transduction
0.53	GO:0007616	long-term memory
0.53	GO:0007409	axonogenesis
0.53	GO:0042752	regulation of circadian rhythm
0.48	GO:0006182	cGMP biosynthetic process
0.41	GO:0008038	neuron recognition
0.41	GO:0007605	sensory perception of sound
0.40	GO:0097485	neuron projection guidance
0.40	GO:1904321	response to forskolin

0.74	GO:0004016	adenylate cyclase activity
0.52	GO:1901265	nucleoside phosphate binding
0.50	GO:0036094	small molecule binding
0.48	GO:0004383	guanylate cyclase activity
0.47	GO:0097367	carbohydrate derivative binding
0.47	GO:0008144	drug binding
0.46	GO:0043168	anion binding
0.38	GO:0005516	calmodulin binding
0.34	GO:0046872	metal ion binding

0.53	GO:0005886	plasma membrane
0.49	GO:0008074	guanylate cyclase complex, soluble
0.38	GO:0045121	membrane raft
0.37	GO:0070062	extracellular exosome
0.35	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.74

EC:4.6.1.1

GO:0004016

sp|Q08830|FGL1_HUMAN
Fibrinogen-like protein 1
Search

FGL1

0.88	Hepatocyte-derived fibrinogen-related protein 1

0.71	GO:0035634	response to stilbenoid
0.68	GO:0060612	adipose tissue development
0.65	GO:0008203	cholesterol metabolic process
0.65	GO:0010906	regulation of glucose metabolic process
0.48	GO:0001889	liver development

0.65	GO:0070062	extracellular exosome
0.59	GO:0005577	fibrinogen complex

sp|Q08881|ITK_HUMAN
Tyrosine-protein kinase ITK/TSK
Search

ITK

0.59	Tyrosine-protein kinase

0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.63	GO:0001865	NK T cell differentiation
0.61	GO:0032633	interleukin-4 production
0.61	GO:0035556	intracellular signal transduction
0.60	GO:0007202	activation of phospholipase C activity
0.60	GO:0032609	interferon-gamma production
0.59	GO:0050851	antigen receptor-mediated signaling pathway
0.56	GO:0002250	adaptive immune response
0.50	GO:0046777	protein autophosphorylation
0.47	GO:0045087	innate immune response

0.80	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0005102	receptor binding
0.36	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.35	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.33	GO:0046872	metal ion binding

0.53	GO:0005911	cell-cell junction
0.48	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.46	GO:0005634	nucleus
0.38	GO:0005856	cytoskeleton
0.35	GO:0005829	cytosol

0.80

GO:0004715

sp|Q08945|SSRP1_HUMAN
FACT complex subunit SSRP1
Search

SSRP1

0.75	FACT complex subunit SSRP1

0.65	GO:0006260	DNA replication
0.64	GO:0006281	DNA repair
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.36	GO:0051726	regulation of cell cycle
0.35	GO:1901796	regulation of signal transduction by p53 class mediator

0.54	GO:0003677	DNA binding
0.53	GO:0003682	chromatin binding
0.34	GO:0005515	protein binding
0.34	GO:0003723	RNA binding

0.67	GO:0005694	chromosome
0.61	GO:0005634	nucleus
0.37	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|Q08999|RBL2_HUMAN
Retinoblastoma-like protein 2
Search

RBL2

0.97	RB transcriptional corepressor like 2

0.73	GO:0051726	regulation of cell cycle
0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.67	GO:0007049	cell cycle
0.59	GO:0043550	regulation of lipid kinase activity
0.50	GO:0010629	negative regulation of gene expression
0.37	GO:0016569	covalent chromatin modification
0.36	GO:0030330	DNA damage response, signal transduction by p53 class mediator
0.35	GO:0006351	transcription, DNA-templated
0.34	GO:0048522	positive regulation of cellular process
0.34	GO:0048523	negative regulation of cellular process

0.60	GO:1990841	promoter-specific chromatin binding
0.36	GO:0005515	protein binding
0.34	GO:0003677	DNA binding

0.75	GO:0005667	transcription factor complex
0.61	GO:0005634	nucleus
0.50	GO:0005829	cytosol
0.49	GO:0031974	membrane-enclosed lumen
0.45	GO:0043232	intracellular non-membrane-bounded organelle
0.44	GO:0044446	intracellular organelle part
0.37	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

sp|Q08AD1|CAMP2_HUMAN
Calmodulin-regulated spectrin-associated protein 2
Search

CAMSAP2

0.92	Calmodulin-regulated spectrin-associated protein 2

0.78	GO:0031175	neuron projection development
0.51	GO:1903358	regulation of Golgi organization
0.49	GO:0031113	regulation of microtubule polymerization
0.49	GO:0050773	regulation of dendrite development
0.46	GO:0000226	microtubule cytoskeleton organization
0.33	GO:0007186	G-protein coupled receptor signaling pathway

0.85	GO:0030507	spectrin binding
0.79	GO:0005516	calmodulin binding
0.74	GO:0008017	microtubule binding
0.34	GO:0004930	G-protein coupled receptor activity

0.72	GO:0005874	microtubule
0.46	GO:0005813	centrosome
0.44	GO:0005794	Golgi apparatus
0.43	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q08AE8|SPIR1_HUMAN
Protein spire homolog 1
Search

SPIRE1

0.95	Spire type actin nucleation factor 1

0.79	GO:0045010	actin nucleation
0.68	GO:0016192	vesicle-mediated transport
0.54	GO:0051295	establishment of meiotic spindle localization
0.42	GO:0040038	polar body extrusion after meiotic divisions
0.42	GO:0070649	formin-nucleated actin cable assembly
0.42	GO:0036089	cleavage furrow formation
0.38	GO:0060996	dendritic spine development
0.38	GO:0001662	behavioral fear response
0.37	GO:0046907	intracellular transport
0.37	GO:0015031	protein transport

0.73

GO:0003779

actin binding

0.45	GO:0005829	cytosol
0.45	GO:0005654	nucleoplasm
0.41	GO:0032154	cleavage furrow
0.40	GO:0030659	cytoplasmic vesicle membrane
0.39	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0005938	cell cortex
0.37	GO:0005856	cytoskeleton
0.36	GO:0005794	Golgi apparatus
0.35	GO:0005886	plasma membrane

sp|Q08AF3|SLFN5_HUMAN
Schlafen family member 5
Search

0.97	Schlafen family member 5

0.54	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle
0.51	GO:0051607	defense response to virus
0.45	GO:0036345	platelet maturation
0.41	GO:0016075	rRNA catabolic process
0.40	GO:0006402	mRNA catabolic process
0.39	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.33	GO:0008285	negative regulation of cell proliferation

0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0000049	tRNA binding
0.40	GO:0043022	ribosome binding
0.39	GO:0004521	endoribonuclease activity

0.55	GO:0005634	nucleus
0.44	GO:0016235	aggresome
0.40	GO:0005829	cytosol
0.39	GO:0031974	membrane-enclosed lumen
0.37	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|Q08AF8|GOG8F_HUMAN
Putative golgin subfamily A member 8F/8G
Search

0.97	Golgin subfamily A member 8M

0.42

GO:0005515

protein binding

0.72	GO:0005794	Golgi apparatus
0.39	GO:0098588	bounding membrane of organelle
0.38	GO:0031984	organelle subcompartment
0.34	GO:0005829	cytosol

sp|Q08AG5|ZN844_HUMAN
Zinc finger protein 844
Search

0.10	Zinc finger protein 844

0.48	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.48	GO:1903506	regulation of nucleic acid-templated transcription
0.48	GO:0010468	regulation of gene expression
0.30	GO:0019438	aromatic compound biosynthetic process
0.30	GO:0006807	nitrogen compound metabolic process
0.30	GO:0046483	heterocycle metabolic process
0.30	GO:0044260	cellular macromolecule metabolic process
0.30	GO:1901360	organic cyclic compound metabolic process
0.30	GO:1901576	organic substance biosynthetic process
0.30	GO:0044238	primary metabolic process

0.51	GO:0003676	nucleic acid binding
0.30	GO:0043167	ion binding
0.30	GO:0005515	protein binding

0.40	GO:0005622	intracellular
0.30	GO:0043226	organelle

sp|Q08AG7|MZT1_HUMAN
Mitotic-spindle organizing protein 1
Search

MZT1

0.92	Mitotic-spindle organizing protein 1

0.85	GO:0033566	gamma-tubulin complex localization
0.54	GO:0051417	microtubule nucleation by spindle pole body
0.54	GO:0051415	microtubule nucleation by interphase microtubule organizing center
0.52	GO:0090307	mitotic spindle assembly
0.34	GO:0006801	superoxide metabolic process
0.34	GO:0043085	positive regulation of catalytic activity
0.32	GO:0055114	oxidation-reduction process

0.51	GO:0043015	gamma-tubulin binding
0.35	GO:0016176	superoxide-generating NADPH oxidase activator activity
0.34	GO:0035091	phosphatidylinositol binding

0.85	GO:0008274	gamma-tubulin ring complex
0.57	GO:0005813	centrosome
0.55	GO:0005819	spindle
0.54	GO:0061495	gamma-tubulin small complex, mitotic spindle pole body
0.54	GO:0031021	interphase microtubule organizing center
0.53	GO:0000923	equatorial microtubule organizing center
0.35	GO:0043020	NADPH oxidase complex
0.34	GO:0005829	cytosol

sp|Q08AH1|ACSM1_HUMAN
Acyl-coenzyme A synthetase ACSM1, mitochondrial
Search

0.86	Acyl-coenzyme A synthetase ACSM1, mitochondrial

0.52	GO:0006633	fatty acid biosynthetic process
0.51	GO:0035383	thioester metabolic process
0.46	GO:0006732	coenzyme metabolic process
0.44	GO:0055088	lipid homeostasis
0.42	GO:1901568	fatty acid derivative metabolic process
0.42	GO:0006793	phosphorus metabolic process
0.41	GO:0006805	xenobiotic metabolic process
0.40	GO:0019605	butyrate metabolic process
0.40	GO:0018874	benzoate metabolic process
0.39	GO:0019395	fatty acid oxidation

0.63	GO:0047760	butyrate-CoA ligase activity
0.62	GO:0003996	acyl-CoA ligase activity
0.59	GO:0004321	fatty-acyl-CoA synthase activity
0.57	GO:0015645	fatty acid ligase activity
0.43	GO:0030554	adenyl nucleotide binding
0.42	GO:0097367	carbohydrate derivative binding
0.42	GO:0008144	drug binding
0.42	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0046872	metal ion binding
0.41	GO:0019001	guanyl nucleotide binding

0.54	GO:0005759	mitochondrial matrix
0.40	GO:0072562	blood microparticle
0.39	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.63

EC:6.2.1.2

GO:0047760

sp|Q08AH3|ACS2A_HUMAN
Acyl-coenzyme A synthetase ACSM2A, mitochondrial
Search

0.89	Acyl-coenzyme A synthetase ACSM2, mitochondrial

0.50	GO:0035383	thioester metabolic process
0.49	GO:0006633	fatty acid biosynthetic process
0.45	GO:1901568	fatty acid derivative metabolic process
0.45	GO:0006732	coenzyme metabolic process
0.42	GO:0055088	lipid homeostasis
0.41	GO:0006793	phosphorus metabolic process
0.41	GO:0006805	xenobiotic metabolic process
0.39	GO:0042593	glucose homeostasis
0.38	GO:0019605	butyrate metabolic process
0.38	GO:0018874	benzoate metabolic process

0.60	GO:0003996	acyl-CoA ligase activity
0.60	GO:0047760	butyrate-CoA ligase activity
0.57	GO:0004321	fatty-acyl-CoA synthase activity
0.54	GO:0015645	fatty acid ligase activity
0.41	GO:0030554	adenyl nucleotide binding
0.41	GO:0032553	ribonucleotide binding
0.41	GO:0008144	drug binding
0.41	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0046872	metal ion binding
0.39	GO:0032550	purine ribonucleoside binding

0.51	GO:0005759	mitochondrial matrix
0.38	GO:0072562	blood microparticle
0.37	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.60

EC:6.2.1

GO:0003996

sp|Q08AI6|S38AB_HUMAN
Putative sodium-coupled neutral amino acid transporter 11
Search

SLC38A11

0.97	Putative sodium-coupled neutral amino acid transporter 11

0.46	GO:0003333	amino acid transmembrane transport
0.40	GO:0006814	sodium ion transport

0.46

GO:0015171

amino acid transmembrane transporter activity

0.30

GO:0031224

intrinsic component of membrane

sp|Q08AI8|CB054_HUMAN
Uncharacterized protein C2orf54
Search

sp|Q08AM6|VAC14_HUMAN
Protein VAC14 homolog
Search

VAC14

0.97	Vac14, PIKFYVE complex component

0.78

GO:0006661

phosphatidylinositol biosynthetic process

0.85	GO:0070772	PAS complex
0.76	GO:0010008	endosome membrane

sp|Q08AN1|ZN616_HUMAN
Zinc finger protein 616
Search

0.76	Zinc finger protein 347

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.37	GO:0006351	transcription, DNA-templated
0.32	GO:0030097	hemopoiesis

0.53	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.41	GO:0003700	DNA binding transcription factor activity
0.35	GO:0005515	protein binding

0.45	GO:0005622	intracellular
0.37	GO:0043227	membrane-bounded organelle
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044422	organelle part

sp|Q08E93|F27E3_HUMAN
Protein FAM27E3
Search

sp|Q08ER8|ZN543_HUMAN
Zinc finger protein 543
Search

0.86	Zinc finger protein 543

0.54	GO:2001141	regulation of RNA biosynthetic process
0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.36	GO:0006351	transcription, DNA-templated
0.34	GO:0006468	protein phosphorylation

0.51	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.36	GO:0005515	protein binding
0.34	GO:0004672	protein kinase activity
0.34	GO:0003700	DNA binding transcription factor activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.43	GO:0005622	intracellular
0.36	GO:0043227	membrane-bounded organelle

sp|Q08ET2|SIG14_HUMAN
Sialic acid-binding Ig-like lectin 14
Search

0.90	Sialic acid binding Ig like lectin 8

0.42	GO:0043312	neutrophil degranulation
0.41	GO:0007155	cell adhesion
0.37	GO:0060101	negative regulation of phagocytosis, engulfment
0.36	GO:0045087	innate immune response
0.36	GO:0050728	negative regulation of inflammatory response
0.36	GO:0006898	receptor-mediated endocytosis
0.36	GO:0023052	signaling
0.36	GO:0007154	cell communication
0.35	GO:0051716	cellular response to stimulus
0.35	GO:0050776	regulation of immune response

0.52	GO:0030246	carbohydrate binding
0.41	GO:0033691	sialic acid binding
0.37	GO:0004872	receptor activity
0.36	GO:0005515	protein binding
0.36	GO:0005057	signal transducer activity, downstream of receptor

0.43	GO:0009986	cell surface
0.41	GO:0070821	tertiary granule membrane
0.41	GO:0098552	side of membrane
0.41	GO:0101003	ficolin-1-rich granule membrane
0.39	GO:0044459	plasma membrane part
0.37	GO:0005634	nucleus
0.35	GO:0035579	specific granule membrane
0.34	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

sp|Q08J23|NSUN2_HUMAN
tRNA (cytosine(34)-C(5))-methyltransferase
Search

NSUN2

0.96	NOP2/Sun RNA methyltransferase family member 2

0.73	GO:0030488	tRNA methylation
0.71	GO:0033313	meiotic cell cycle checkpoint
0.71	GO:0048820	hair follicle maturation
0.68	GO:0007286	spermatid development

0.85	GO:0016428	tRNA (cytosine-5-)-methyltransferase activity
0.59	GO:0003723	RNA binding

0.73	GO:0033391	chromatoid body
0.61	GO:0005730	nucleolus

0.85

GO:0016428

sp|Q09013|DMPK_HUMAN
Myotonin-protein kinase
Search

DMPK

0.97	Dystrophia myotonica-protein kinase

0.63	GO:0006468	protein phosphorylation
0.58	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling
0.57	GO:0014853	regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction
0.56	GO:0010657	muscle cell apoptotic process
0.55	GO:0051823	regulation of synapse structural plasticity
0.54	GO:0006998	nuclear envelope organization
0.53	GO:0010830	regulation of myotube differentiation
0.53	GO:0008016	regulation of heart contraction
0.53	GO:0002028	regulation of sodium ion transport
0.52	GO:0006874	cellular calcium ion homeostasis

0.70	GO:0004674	protein serine/threonine kinase activity
0.56	GO:0017020	myosin phosphatase regulator activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0046872	metal ion binding
0.38	GO:0031072	heat shock protein binding
0.37	GO:0042802	identical protein binding
0.33	GO:0032403	protein complex binding

0.55	GO:0033017	sarcoplasmic reticulum membrane
0.53	GO:0031307	integral component of mitochondrial outer membrane
0.43	GO:0031965	nuclear membrane
0.41	GO:0005886	plasma membrane
0.39	GO:0042641	actomyosin
0.36	GO:0005829	cytosol
0.35	GO:0030027	lamellipodium
0.33	GO:0070062	extracellular exosome
0.33	GO:0005911	cell-cell junction

0.70

GO:0004674

sp|Q09019|DMWD_HUMAN
Dystrophia myotonica WD repeat-containing protein
Search

WDR20

0.89	Dystrophia myotonica, WD repeat containing

0.73	GO:0016579	protein deubiquitination
0.40	GO:0006468	protein phosphorylation

0.41	GO:0004674	protein serine/threonine kinase activity
0.40	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.37	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0005515	protein binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0003676	nucleic acid binding

0.54	GO:0043204	perikaryon
0.52	GO:0030425	dendrite
0.45	GO:0005634	nucleus
0.38	GO:0031974	membrane-enclosed lumen
0.36	GO:0044446	intracellular organelle part

0.41

GO:0004674

sp|Q09028|RBBP4_HUMAN
Histone-binding protein RBBP4
Search

RBBP4

0.88	RB binding protein 4, chromatin remodeling factor

0.49	GO:0006335	DNA replication-dependent nucleosome assembly
0.47	GO:0006336	DNA replication-independent nucleosome assembly
0.46	GO:0006338	chromatin remodeling
0.40	GO:0016569	covalent chromatin modification
0.39	GO:0006260	DNA replication
0.38	GO:0007049	cell cycle
0.38	GO:0060416	response to growth hormone
0.37	GO:0006351	transcription, DNA-templated
0.37	GO:1903506	regulation of nucleic acid-templated transcription
0.37	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.47	GO:0042826	histone deacetylase binding
0.43	GO:0008094	DNA-dependent ATPase activity
0.36	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.36	GO:0031492	nucleosomal DNA binding
0.36	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.34	GO:0004407	histone deacetylase activity
0.34	GO:0042393	histone binding

0.61	GO:0005634	nucleus
0.52	GO:0033186	CAF-1 complex
0.48	GO:0034708	methyltransferase complex
0.46	GO:0017053	transcriptional repressor complex
0.44	GO:0031974	membrane-enclosed lumen
0.43	GO:0000785	chromatin
0.42	GO:0005829	cytosol
0.41	GO:1904949	ATPase complex
0.30	GO:0016021	integral component of membrane

0.34

EC:3.5.1.98

GO:0004407

sp|Q09161|NCBP1_HUMAN
Nuclear cap-binding protein subunit 1
Search

NCBP1

0.91	LOW QUALITY PROTEIN: nuclear cap-binding protein subunit 1

0.79	GO:0045292	mRNA cis splicing, via spliceosome
0.73	GO:0051028	mRNA transport
0.57	GO:0031442	positive regulation of mRNA 3'-end processing
0.56	GO:1905216	positive regulation of RNA binding
0.56	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.55	GO:0098789	pre-mRNA cleavage required for polyadenylation
0.55	GO:0048026	positive regulation of mRNA splicing, via spliceosome
0.55	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.53	GO:0030307	positive regulation of cell growth
0.52	GO:0006405	RNA export from nucleus

0.80	GO:0000339	RNA cap binding
0.45	GO:0003729	mRNA binding
0.35	GO:0005515	protein binding

0.80	GO:0005846	nuclear cap binding complex
0.57	GO:0005845	mRNA cap binding complex
0.47	GO:0005654	nucleoplasm
0.47	GO:0005829	cytosol
0.45	GO:0030529	intracellular ribonucleoprotein complex
0.43	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

sp|Q09327|MGAT3_HUMAN
Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase
Search

MGAT3

0.95	N-acetylglucosaminyltransferase III

0.80	GO:0006487	protein N-linked glycosylation
0.37	GO:0060070	canonical Wnt signaling pathway
0.36	GO:0006044	N-acetylglucosamine metabolic process
0.32	GO:0016311	dephosphorylation
0.32	GO:0005975	carbohydrate metabolic process

0.85	GO:0003830	beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity
0.33	GO:0042132	fructose 1,6-bisphosphate 1-phosphatase activity

0.37	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

0.85

EC:2.4.1.144

GO:0003830

sp|Q09328|MGT5A_HUMAN
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A
Search

MGAT5

0.96	Mannoside acetylglucosaminyltransferase 5

0.80	GO:0006487	protein N-linked glycosylation
0.49	GO:0070658	neuromast hair cell differentiation involved in neuromast regeneration

0.86

GO:0030144

alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity

0.51	GO:0005794	Golgi apparatus
0.37	GO:0098588	bounding membrane of organelle
0.37	GO:0031984	organelle subcompartment
0.37	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.86

EC:2.4.1.155

GO:0030144

sp|Q09428|ABCC8_HUMAN
ATP-binding cassette sub-family C member 8
Search

ABCC8

0.96	Sulphonylurea receptor 1

0.71	GO:0006813	potassium ion transport
0.61	GO:0007165	signal transduction
0.55	GO:0055085	transmembrane transport
0.43	GO:0042493	response to drug
0.41	GO:1905604	negative regulation of maintenance of permeability of blood-brain barrier
0.41	GO:0061855	negative regulation of neuroblast migration
0.41	GO:1900719	regulation of uterine smooth muscle relaxation
0.41	GO:1901082	positive regulation of relaxation of smooth muscle
0.40	GO:1905075	positive regulation of occluding junction disassembly
0.40	GO:0010989	negative regulation of low-density lipoprotein particle clearance

0.86	GO:0008281	sulfonylurea receptor activity
0.66	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.56	GO:0044325	ion channel binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.54	GO:0005267	potassium channel activity
0.38	GO:0019905	syntaxin binding
0.36	GO:0099094	ligand-gated cation channel activity

0.61	GO:0008282	inward rectifying potassium channel
0.49	GO:0042383	sarcolemma
0.45	GO:0008076	voltage-gated potassium channel complex
0.39	GO:0030672	synaptic vesicle membrane
0.35	GO:0005739	mitochondrion
0.34	GO:0030017	sarcomere

sp|Q09470|KCNA1_HUMAN
Potassium voltage-gated channel subfamily A member 1
Search

KCNA1

0.92	Potassium channel

0.77	GO:0051260	protein homooligomerization
0.76	GO:0034765	regulation of ion transmembrane transport
0.72	GO:0071805	potassium ion transmembrane transport
0.57	GO:0071286	cellular response to magnesium ion
0.56	GO:0010960	magnesium ion homeostasis
0.56	GO:0050966	detection of mechanical stimulus involved in sensory perception of pain
0.56	GO:0050976	detection of mechanical stimulus involved in sensory perception of touch
0.56	GO:0019228	neuronal action potential
0.55	GO:0001964	startle response
0.54	GO:0007405	neuroblast proliferation

0.77	GO:0005249	voltage-gated potassium channel activity
0.56	GO:0097718	disordered domain specific binding
0.34	GO:0019894	kinesin binding

0.77	GO:0008076	voltage-gated potassium channel complex
0.61	GO:0044224	juxtaparanode region of axon
0.57	GO:0043679	axon terminus
0.57	GO:0033270	paranode region of axon
0.55	GO:0043025	neuronal cell body
0.55	GO:0030425	dendrite
0.50	GO:0030054	cell junction
0.50	GO:0009986	cell surface
0.45	GO:0044298	cell body membrane
0.40	GO:0042734	presynaptic membrane

sp|Q09472|EP300_HUMAN
Histone acetyltransferase p300
Search

0.80	Histone acetyltransferase p300

0.78	GO:0016573	histone acetylation
0.59	GO:0140066	peptidyl-lysine crotonylation
0.59	GO:0140067	peptidyl-lysine butyrylation
0.59	GO:0061921	peptidyl-lysine propionylation
0.58	GO:0018076	N-terminal peptidyl-lysine acetylation
0.57	GO:0010742	macrophage derived foam cell differentiation
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:0090043	regulation of tubulin deacetylation
0.56	GO:0010468	regulation of gene expression

0.80	GO:0004402	histone acetyltransferase activity
0.78	GO:0003713	transcription coactivator activity
0.63	GO:0008270	zinc ion binding
0.59	GO:0140064	peptide crotonyltransferase activity
0.59	GO:0140065	peptide butyryltransferase activity
0.59	GO:0061920	protein propionyltransferase activity
0.57	GO:0097677	STAT family protein binding
0.57	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor
0.56	GO:0050681	androgen receptor binding
0.55	GO:0097157	pre-mRNA intronic binding

0.75	GO:0000123	histone acetyltransferase complex
0.48	GO:0005667	transcription factor complex
0.47	GO:0005829	cytosol
0.32	GO:0045211	postsynaptic membrane
0.32	GO:0030054	cell junction
0.30	GO:0005694	chromosome
0.30	GO:0016021	integral component of membrane
0.30	GO:0032993	protein-DNA complex

0.80

GO:0004402

sp|Q09666|AHNK_HUMAN
Neuroblast differentiation-associated protein AHNAK
Search

AHNAK

0.85	Neuroblast differentiation-associated protein AHNAK

0.85	GO:1901385	regulation of voltage-gated calcium channel activity
0.75	GO:0043484	regulation of RNA splicing
0.67	GO:0051259	protein oligomerization
0.35	GO:0055114	oxidation-reduction process

0.85	GO:0044548	S100 protein binding
0.83	GO:0097493	structural molecule activity conferring elasticity
0.79	GO:0045296	cadherin binding
0.44	GO:0003723	RNA binding
0.35	GO:0016491	oxidoreductase activity

0.83	GO:0044291	cell-cell contact zone
0.82	GO:0042383	sarcolemma
0.82	GO:0043034	costamere
0.79	GO:0070062	extracellular exosome
0.78	GO:0045121	membrane raft
0.72	GO:0015629	actin cytoskeleton
0.67	GO:0005829	cytosol
0.57	GO:0005634	nucleus
0.54	GO:0005765	lysosomal membrane
0.54	GO:0005925	focal adhesion

0.35

EC:1

GO:0016491

sp|Q09FC8|ZN415_HUMAN
Zinc finger protein 415
Search

ZNF880

0.79	Zinc finger protein 880

0.51	GO:1903506	regulation of nucleic acid-templated transcription
0.51	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.51	GO:0010468	regulation of gene expression
0.30	GO:0090304	nucleic acid metabolic process
0.30	GO:0018130	heterocycle biosynthetic process
0.30	GO:1901362	organic cyclic compound biosynthetic process
0.30	GO:0019438	aromatic compound biosynthetic process
0.30	GO:0044260	cellular macromolecule metabolic process
0.30	GO:0009059	macromolecule biosynthetic process
0.30	GO:0044271	cellular nitrogen compound biosynthetic process

0.51	GO:0003676	nucleic acid binding
0.48	GO:0046872	metal ion binding
0.42	GO:0003700	DNA binding transcription factor activity
0.30	GO:0005515	protein binding

0.42	GO:0005622	intracellular
0.30	GO:0031974	membrane-enclosed lumen
0.30	GO:0043228	non-membrane-bounded organelle
0.30	GO:0043227	membrane-bounded organelle
0.30	GO:0044422	organelle part

sp|Q09MP3|R51A2_HUMAN
RAD51-associated protein 2
Search

RAD51AP2

0.97	RAD51-associated protein 2

0.40

GO:0005515

protein binding

0.60

GO:0043234

protein complex

sp|Q0D2H9|GOG8D_HUMAN
Putative golgin subfamily A member 8D
Search

0.97	Golgin subfamily A member 8M

0.42

GO:0005515

protein binding

0.72	GO:0005794	Golgi apparatus
0.39	GO:0098588	bounding membrane of organelle
0.38	GO:0031984	organelle subcompartment
0.34	GO:0005829	cytosol

sp|Q0D2I5|IFFO1_HUMAN
Intermediate filament family orphan 1
Search

IFFO1

0.92	Intermediate filament family orphan 1

0.62

GO:0005198

structural molecule activity

0.79

GO:0005882

intermediate filament

sp|Q0D2J5|ZN763_HUMAN
Zinc finger protein 763
Search

0.79	Zinc finger protein 823

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.39	GO:0006351	transcription, DNA-templated
0.35	GO:1902679	negative regulation of RNA biosynthetic process
0.33	GO:0007186	G-protein coupled receptor signaling pathway

0.51	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.37	GO:0005515	protein binding
0.36	GO:0003714	transcription corepressor activity
0.34	GO:0003700	DNA binding transcription factor activity
0.33	GO:0004930	G-protein coupled receptor activity

0.44	GO:0005622	intracellular
0.38	GO:0043227	membrane-bounded organelle
0.30	GO:0016020	membrane
0.30	GO:0005576	extracellular region

sp|Q0D2K0|NIPA4_HUMAN
Magnesium transporter NIPA4
Search

NIPAL4

0.97	Non imprinted in Prader-Willi/Angelman syndrome 2

0.77

GO:1903830

magnesium ion transmembrane transport

0.77	GO:0015095	magnesium ion transmembrane transporter activity
0.33	GO:0005515	protein binding

0.45	GO:0005769	early endosome
0.38	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q0D2K2|KLH30_HUMAN
Kelch-like protein 30
Search

KLHL30

0.97	Kelch like family member 30

0.73

GO:0016567

protein ubiquitination

0.74

GO:0004842

ubiquitin-protein transferase activity

0.83

GO:0031463

Cul3-RING ubiquitin ligase complex

0.74

GO:0004842

sp|Q0D2K3|RIPP1_HUMAN
Protein ripply1
Search

RIPPLY1

0.97	Ripply transcriptional repressor 1

0.84	GO:0009880	embryonic pattern specification
0.77	GO:0001756	somitogenesis
0.77	GO:0060349	bone morphogenesis
0.76	GO:0009948	anterior/posterior axis specification
0.74	GO:0007219	Notch signaling pathway
0.73	GO:0036342	post-anal tail morphogenesis
0.70	GO:0000122	negative regulation of transcription by RNA polymerase II
0.69	GO:0007368	determination of left/right symmetry
0.69	GO:0001503	ossification

0.56

GO:0005634

nucleus

sp|Q0D2K5|EGFEM_HUMAN
Putative EGF-like and EMI domain-containing protein 1
Search

0.11	Putative EGF-like and EMI domain-containing protein 1

0.39	GO:0006030	chitin metabolic process
0.37	GO:0007155	cell adhesion
0.36	GO:0045995	regulation of embryonic development
0.35	GO:0030334	regulation of cell migration
0.35	GO:0030155	regulation of cell adhesion
0.35	GO:0050482	arachidonic acid secretion
0.34	GO:0006955	immune response
0.34	GO:0006898	receptor-mediated endocytosis
0.34	GO:0006644	phospholipid metabolic process
0.34	GO:0006508	proteolysis

0.69	GO:0005509	calcium ion binding
0.38	GO:0008061	chitin binding
0.35	GO:0005044	scavenger receptor activity
0.35	GO:0004623	phospholipase A2 activity
0.35	GO:0001871	pattern binding
0.35	GO:0005102	receptor binding
0.34	GO:0004252	serine-type endopeptidase activity
0.34	GO:0005216	ion channel activity
0.34	GO:0030246	carbohydrate binding
0.33	GO:0004672	protein kinase activity

0.38	GO:0005576	extracellular region
0.36	GO:0001669	acrosomal vesicle
0.30	GO:0016020	membrane

0.35

EC:3.1.1.4

GO:0004623

sp|Q0GE19|NTCP7_HUMAN
Sodium/bile acid cotransporter 7
Search

SLC10A7

0.92	Sodium/bile acid cotransporter

0.40	GO:0006814	sodium ion transport
0.36	GO:0055085	transmembrane transport

0.40

GO:0015293

symporter activity

0.30

GO:0031224

intrinsic component of membrane

sp|Q0IIM8|TBC8B_HUMAN
TBC1 domain family member 8B
Search

TBC1D8B

0.96	TBC1 domain family, member 8B (With GRAM domain)

0.52	GO:0031338	regulation of vesicle fusion
0.52	GO:0090630	activation of GTPase activity
0.46	GO:0006886	intracellular protein transport
0.36	GO:1902017	regulation of cilium assembly
0.34	GO:0008015	blood circulation
0.34	GO:0008284	positive regulation of cell proliferation

0.67	GO:0005509	calcium ion binding
0.51	GO:0017137	Rab GTPase binding
0.49	GO:0005096	GTPase activator activity

0.45	GO:0012505	endomembrane system
0.36	GO:0005622	intracellular
0.30	GO:0016020	membrane

sp|Q0IIN9|ZNFS1_HUMAN
Putative uncharacterized protein ZNF252P-AS1
Search

sp|Q0JRZ9|FCHO2_HUMAN
F-BAR domain only protein 2
Search

FCHO2

0.93	F-BAR domain only protein 2

0.71	GO:0072583	clathrin-dependent endocytosis
0.59	GO:0010324	membrane invagination
0.59	GO:0048488	synaptic vesicle endocytosis
0.58	GO:0072659	protein localization to plasma membrane
0.57	GO:0048268	clathrin coat assembly
0.34	GO:0043009	chordate embryonic development
0.34	GO:0015031	protein transport

0.60	GO:0001786	phosphatidylserine binding
0.59	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.53	GO:0042802	identical protein binding

0.57	GO:0005905	clathrin-coated pit
0.55	GO:0030136	clathrin-coated vesicle
0.53	GO:0045202	synapse
0.44	GO:0005886	plasma membrane
0.38	GO:0097458	neuron part
0.34	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

sp|Q0P140|YA037_HUMAN
Putative uncharacterized protein HSD52
Search

sp|Q0P5N6|ARL16_HUMAN
ADP-ribosylation factor-like protein 16
Search

ARL16

0.97	ADP ribosylation factor like GTPase 16

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005515	protein binding

0.44	GO:0005622	intracellular
0.30	GO:0044425	membrane part

sp|Q0P5P2|CQ067_HUMAN
Uncharacterized protein C17orf67
Search

0.45

GO:0005515

protein binding

0.55	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

sp|Q0P641|CB080_HUMAN
Uncharacterized protein C2orf80
Search

0.57	GO:0006102	isocitrate metabolic process
0.42	GO:0055114	oxidation-reduction process

0.56	GO:0004450	isocitrate dehydrogenase (NADP+) activity
0.50	GO:0051287	NAD binding
0.48	GO:0000287	magnesium ion binding

0.56

EC:1.1.1.42

GO:0004450

sp|Q0P651|ABD18_HUMAN
Protein ABHD18
Search

ABHD18

0.88	Abhydrolase domain containing 18

0.59

GO:0005576

extracellular region

sp|Q0P670|CQ074_HUMAN
Uncharacterized protein C17orf74
Search

0.40	GO:0023051	regulation of signaling
0.40	GO:0010646	regulation of cell communication
0.39	GO:0050808	synapse organization
0.37	GO:0007155	cell adhesion
0.37	GO:0048583	regulation of response to stimulus
0.36	GO:0065009	regulation of molecular function

0.40	GO:0005102	receptor binding
0.38	GO:0030545	receptor regulator activity

0.40	GO:0060077	inhibitory synapse
0.36	GO:0005887	integral component of plasma membrane

sp|Q0P6D2|FA69C_HUMAN
Protein FAM69C
Search

0.45	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q0P6D6|CCD15_HUMAN
Coiled-coil domain-containing protein 15
Search

CCDC15

0.80	Coiled-coil domain-containing protein 15

0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:0010468	regulation of gene expression

0.35	GO:0003713	transcription coactivator activity
0.33	GO:0003677	DNA binding

0.77	GO:0005813	centrosome
0.30	GO:0044425	membrane part

sp|Q0P6H9|TMM62_HUMAN
Transmembrane protein 62
Search

TMEM62

0.70	Transmembrane protein 62

0.33	GO:0000245	spliceosomal complex assembly
0.32	GO:0055085	transmembrane transport

0.50

GO:0016787

hydrolase activity

0.32	GO:0005634	nucleus
0.30	GO:0044425	membrane part

0.50

GO:0016787

sp|Q0PNE2|ELP6_HUMAN
Elongator complex protein 6
Search

ELP6

0.93	Elongator acetyltransferase complex subunit 6

0.77	GO:0002098	tRNA wobble uridine modification
0.59	GO:0030335	positive regulation of cell migration
0.36	GO:0097659	nucleic acid-templated transcription
0.36	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.36	GO:1903506	regulation of nucleic acid-templated transcription
0.36	GO:0010468	regulation of gene expression
0.35	GO:0034645	cellular macromolecule biosynthetic process

0.35

GO:0016740

transferase activity

0.82	GO:0033588	Elongator holoenzyme complex
0.30	GO:0031224	intrinsic component of membrane

0.35

GO:0016740

sp|Q0VAA2|LR74A_HUMAN
Leucine-rich repeat-containing protein 74A
Search

LRRC74A

0.97	leucine-rich repeat-containing protein 74

0.37	GO:0043043	peptide biosynthetic process
0.36	GO:0044267	cellular protein metabolic process
0.35	GO:0010467	gene expression
0.35	GO:0015074	DNA integration
0.35	GO:0009059	macromolecule biosynthetic process
0.33	GO:0016310	phosphorylation

0.67	GO:0005509	calcium ion binding
0.37	GO:0003735	structural constituent of ribosome
0.33	GO:0003676	nucleic acid binding
0.33	GO:0016301	kinase activity

0.37	GO:0005840	ribosome
0.34	GO:0009941	chloroplast envelope
0.33	GO:0005739	mitochondrion

sp|Q0VAA5|PLCX2_HUMAN
PI-PLC X domain-containing protein 2
Search

PLCXD2

0.97	Phosphatidylinositol specific phospholipase C X domain containing 2

0.63	GO:0006629	lipid metabolic process
0.36	GO:1901575	organic substance catabolic process
0.36	GO:0007165	signal transduction

0.73	GO:0008081	phosphoric diester hydrolase activity
0.36	GO:0004871	signal transducer activity
0.33	GO:0008410	CoA-transferase activity

0.35	GO:0005737	cytoplasm
0.34	GO:0005634	nucleus

0.73

EC:3.1.4

GO:0008081

sp|Q0VAF6|SYCN_HUMAN
Syncollin
Search

SYCN

0.97

Syncollin

0.77	GO:0006887	exocytosis
0.40	GO:0017158	regulation of calcium ion-dependent exocytosis
0.39	GO:0007259	JAK-STAT cascade
0.38	GO:0050778	positive regulation of immune response
0.37	GO:0051607	defense response to virus
0.37	GO:0010469	regulation of receptor activity
0.34	GO:0055114	oxidation-reduction process

0.38	GO:0005125	cytokine activity
0.36	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.36	GO:0004497	monooxygenase activity
0.35	GO:0020037	heme binding
0.35	GO:0005506	iron ion binding

0.85	GO:0030667	secretory granule membrane
0.46	GO:0030658	transport vesicle membrane

0.36

EC:1.14

GO:0016705

sp|Q0VAK6|LMOD3_HUMAN
Leiomodin-3
Search

LMOD3

0.96	Leiomodin-3

0.85	GO:0051694	pointed-end actin filament capping
0.67	GO:0030239	myofibril assembly
0.65	GO:0048743	positive regulation of skeletal muscle fiber development
0.64	GO:0006936	muscle contraction
0.62	GO:0048741	skeletal muscle fiber development
0.61	GO:0045010	actin nucleation
0.45	GO:0030041	actin filament polymerization

0.85	GO:0005523	tropomyosin binding
0.80	GO:0003785	actin monomer binding

0.66	GO:0031430	M band
0.63	GO:0005865	striated muscle thin filament
0.44	GO:0005884	actin filament
0.34	GO:0097512	cardiac myofibril

sp|Q0VAM2|RGF1B_HUMAN
Ras-GEF domain-containing family member 1B
Search

RASGEF1B

0.96	Ras-GEF domain-containing family member 1B-A

0.76	GO:0007264	small GTPase mediated signal transduction
0.70	GO:0043547	positive regulation of GTPase activity

0.75	GO:0005085	guanyl-nucleotide exchange factor activity
0.50	GO:0017016	Ras GTPase binding

0.45	GO:0005622	intracellular
0.39	GO:0030496	midbody
0.37	GO:0031982	vesicle
0.37	GO:0012505	endomembrane system

sp|Q0VAQ4|SMAGP_HUMAN
Small cell adhesion glycoprotein
Search

SMAGP

0.97	small cell adhesion glycoprotein isoform X1

0.57	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.53	GO:0008037	cell recognition
0.53	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules

0.53	GO:0050839	cell adhesion molecule binding
0.51	GO:0042803	protein homodimerization activity
0.50	GO:0005102	receptor binding
0.46	GO:0004872	receptor activity

0.64	GO:0030054	cell junction
0.60	GO:0005654	nucleoplasm
0.49	GO:0005886	plasma membrane
0.45	GO:0030659	cytoplasmic vesicle membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q0VD83|APOBR_HUMAN
Apolipoprotein B receptor
Search

APOBR

0.96	Apolipoprotein B receptor

0.74	GO:0006869	lipid transport
0.72	GO:0006898	receptor-mediated endocytosis
0.58	GO:0006641	triglyceride metabolic process
0.50	GO:0034447	very-low-density lipoprotein particle clearance
0.48	GO:0008203	cholesterol metabolic process

0.86	GO:0030228	lipoprotein particle receptor activity
0.50	GO:0030226	apolipoprotein receptor activity
0.44	GO:0042803	protein homodimerization activity

0.50	GO:0034362	low-density lipoprotein particle
0.49	GO:0042627	chylomicron
0.49	GO:0034361	very-low-density lipoprotein particle
0.39	GO:0005886	plasma membrane

sp|Q0VD86|INCA1_HUMAN
Protein INCA1
Search

sp|Q0VDD5|CQ091_HUMAN
Putative uncharacterized protein encoded by MIR22HG
Search

sp|Q0VDD7|CS057_HUMAN
Uncharacterized protein C19orf57
Search

sp|Q0VDD8|DYH14_HUMAN
Dynein heavy chain 14, axonemal
Search

0.76	Dynein heavy chain 14, axonemal

0.74	GO:0007018	microtubule-based movement
0.66	GO:0060271	cilium assembly
0.48	GO:0001539	cilium or flagellum-dependent cell motility

0.75	GO:0003777	microtubule motor activity
0.73	GO:0045503	dynein light chain binding
0.72	GO:0051959	dynein light intermediate chain binding
0.72	GO:0045505	dynein intermediate chain binding
0.58	GO:0016887	ATPase activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005509	calcium ion binding

0.75	GO:0030286	dynein complex
0.69	GO:0005929	cilium
0.60	GO:0005874	microtubule
0.53	GO:0032838	plasma membrane bounded cell projection cytoplasm

0.58

GO:0016887

sp|Q0VDE8|ADIG_HUMAN
Adipogenin
Search

ADIG

0.97	LOW QUALITY PROTEIN: adipogenin

0.85	GO:0045444	fat cell differentiation
0.72	GO:0045600	positive regulation of fat cell differentiation
0.67	GO:0007283	spermatogenesis

0.68	GO:0005811	lipid droplet
0.53	GO:0005634	nucleus
0.44	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q0VDF9|HSP7E_HUMAN
Heat shock 70 kDa protein 14
Search

HSPA14

0.94	Heat shock protein 14

0.36	GO:0051083	'de novo' cotranslational protein folding
0.35	GO:0034968	histone lysine methylation

0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0018024	histone-lysine N-methyltransferase activity
0.33	GO:0005515	protein binding
0.33	GO:0008270	zinc ion binding

0.52	GO:0005829	cytosol
0.48	GO:0005840	ribosome
0.34	GO:0005694	chromosome
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.35

GO:0018024

sp|Q0VDG4|SCRN3_HUMAN
Secernin-3
Search

SCRN3

0.97	Secernin-3

0.61	GO:0006508	proteolysis
0.47	GO:0006887	exocytosis

0.77

GO:0016805

dipeptidase activity

0.38	GO:0031965	nuclear membrane
0.32	GO:0005737	cytoplasm

0.77

EC:3.4.13

GO:0016805

sp|Q0VDI3|TM267_HUMAN
Transmembrane protein 267
Search

TMEM267

0.69	Transmembrane protein 267

0.34

GO:0019221

cytokine-mediated signaling pathway

0.35

GO:0004896

cytokine receptor activity

0.30

GO:0044425

membrane part

sp|Q0VF49|K2012_HUMAN
Uncharacterized protein KIAA2012
Search

sp|Q0VF96|CGNL1_HUMAN
Cingulin-like protein 1
Search

CGNL1

0.79	Cingulin-like protein 1 isoform B

0.48	GO:0051058	negative regulation of small GTPase mediated signal transduction
0.45	GO:0007015	actin filament organization

0.73	GO:0003774	motor activity
0.36	GO:0005515	protein binding

0.77	GO:0016459	myosin complex
0.43	GO:0005923	bicellular tight junction

sp|Q0VFX4|YL016_HUMAN
Putative uncharacterized protein LOC100128554
Search

sp|Q0VFZ6|CC173_HUMAN
Coiled-coil domain-containing protein 173
Search

CCDC173

0.96	Coiled-coil domain-containing protein 173

0.51	GO:0032259	methylation
0.44	GO:0006928	movement of cell or subcellular component
0.43	GO:0007017	microtubule-based process
0.42	GO:0006936	muscle contraction
0.40	GO:0001570	vasculogenesis
0.40	GO:0001947	heart looping
0.40	GO:0090132	epithelium migration
0.39	GO:0001525	angiogenesis
0.39	GO:0010952	positive regulation of peptidase activity
0.38	GO:0006302	double-strand break repair

0.51	GO:0008168	methyltransferase activity
0.44	GO:0003676	nucleic acid binding
0.44	GO:0003777	microtubule motor activity
0.42	GO:0017022	myosin binding
0.41	GO:0005516	calmodulin binding
0.40	GO:0003779	actin binding
0.39	GO:0070577	lysine-acetylated histone binding
0.39	GO:0016504	peptidase activator activity
0.39	GO:0070628	proteasome binding
0.37	GO:0004828	serine-tRNA ligase activity

0.38

GO:0005581

collagen trimer

0.51

GO:0008168

sp|Q0VG06|FP100_HUMAN
Fanconi anemia core complex-associated protein 100
Search

FAAP100

0.97	Fanconi anemia core complex-associated protein 100

0.65

GO:0006281

DNA repair

0.35	GO:0005515	protein binding
0.35	GO:0003677	DNA binding

0.85	GO:0043240	Fanconi anaemia nuclear complex
0.59	GO:0045111	intermediate filament cytoskeleton
0.53	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q0VG73|YC023_HUMAN
Putative uncharacterized protein LOC152225
Search

sp|Q0VG99|MESP2_HUMAN
Mesoderm posterior protein 2
Search

MESP2

0.93	Mesoderm posterior bHLH transcription factor 2

0.62	GO:0001756	somitogenesis
0.59	GO:0007498	mesoderm development
0.58	GO:0007369	gastrulation
0.58	GO:0009880	embryonic pattern specification
0.57	GO:0045944	positive regulation of transcription by RNA polymerase II
0.57	GO:0006366	transcription by RNA polymerase II
0.57	GO:0003007	heart morphogenesis
0.56	GO:0048729	tissue morphogenesis
0.51	GO:0007379	segment specification
0.50	GO:0003235	sinus venosus development

0.68	GO:0046983	protein dimerization activity
0.60	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.57	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.57	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.46	GO:0035326	enhancer binding
0.45	GO:0003682	chromatin binding
0.33	GO:0016651	oxidoreductase activity, acting on NAD(P)H
0.32	GO:0004519	endonuclease activity

0.47	GO:0005634	nucleus
0.40	GO:0070062	extracellular exosome

0.33

EC:1.6

GO:0016651

sp|Q0VGE8|ZN816_HUMAN
Zinc finger protein 816
Search

0.59	Zinc finger protein 726

0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:0010468	regulation of gene expression
0.36	GO:0097659	nucleic acid-templated transcription
0.35	GO:0010467	gene expression
0.35	GO:0034645	cellular macromolecule biosynthetic process

0.51	GO:0003676	nucleic acid binding
0.50	GO:0046872	metal ion binding
0.37	GO:0005515	protein binding
0.37	GO:0003700	DNA binding transcription factor activity

0.44	GO:0005622	intracellular
0.36	GO:0043227	membrane-bounded organelle

sp|Q0VGL1|LTOR4_HUMAN
Ragulator complex protein LAMTOR4
Search

LAMTOR4

0.96	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4

0.84	GO:0071230	cellular response to amino acid stimulus
0.81	GO:0032008	positive regulation of TOR signaling
0.60	GO:0061462	protein localization to lysosome
0.56	GO:0008361	regulation of cell size
0.48	GO:0065009	regulation of molecular function
0.36	GO:0016241	regulation of macroautophagy
0.36	GO:0007050	cell cycle arrest

0.56	GO:0032947	protein complex scaffold activity
0.53	GO:0005085	guanyl-nucleotide exchange factor activity

0.85	GO:0071986	Ragulator complex
0.55	GO:0005764	lysosome
0.35	GO:0098852	lytic vacuole membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q0WX57|U17LO_HUMAN
Ubiquitin carboxyl-terminal hydrolase 17-like protein 24
Search

0.92	Ubiquitin carboxyl-terminal hydrolase 17

0.76	GO:0016579	protein deubiquitination
0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.41	GO:0006915	apoptotic process
0.38	GO:1904035	regulation of epithelial cell apoptotic process
0.37	GO:0007283	spermatogenesis
0.36	GO:1900245	positive regulation of MDA-5 signaling pathway
0.36	GO:0090315	negative regulation of protein targeting to membrane
0.36	GO:0031064	negative regulation of histone deacetylation
0.36	GO:1900246	positive regulation of RIG-I signaling pathway
0.36	GO:1900027	regulation of ruffle assembly

0.77	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.38	GO:0005540	hyaluronic acid binding
0.34	GO:0003723	RNA binding
0.34	GO:0005515	protein binding
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0032561	guanyl ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.47	GO:0005783	endoplasmic reticulum
0.44	GO:0005634	nucleus
0.35	GO:0043233	organelle lumen
0.34	GO:0044446	intracellular organelle part
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0005829	cytosol
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.77

EC:3.4.19.12

GO:0036459

sp|Q0Z7S8|FABP9_HUMAN
Fatty acid-binding protein 9
Search

FABP9

0.83	Fatty acid-binding protein, adipocyte

0.56	GO:0061024	membrane organization
0.53	GO:0050727	regulation of inflammatory response
0.47	GO:0050872	white fat cell differentiation
0.47	GO:0071285	cellular response to lithium ion
0.45	GO:0042632	cholesterol homeostasis
0.45	GO:0001816	cytokine production
0.45	GO:0071356	cellular response to tumor necrosis factor
0.44	GO:0032103	positive regulation of response to external stimulus
0.44	GO:0006469	negative regulation of protein kinase activity
0.44	GO:0031349	positive regulation of defense response

0.72	GO:0008289	lipid binding
0.55	GO:0033293	monocarboxylic acid binding
0.50	GO:0043178	alcohol binding
0.36	GO:0097159	organic cyclic compound binding
0.33	GO:0005515	protein binding

0.66	GO:0043209	myelin sheath
0.37	GO:0031982	vesicle
0.36	GO:0043230	extracellular organelle
0.36	GO:0097223	sperm part
0.35	GO:0005615	extracellular space
0.34	GO:0005829	cytosol
0.34	GO:0012505	endomembrane system
0.34	GO:0005811	lipid droplet
0.33	GO:0005634	nucleus

sp|Q0ZGT2|NEXN_HUMAN
Nexilin
Search

NEXN

0.94	Nexilin (F actin binding protein)

0.76	GO:0030334	regulation of cell migration
0.73	GO:0051493	regulation of cytoskeleton organization
0.72	GO:0048739	cardiac muscle fiber development
0.46	GO:0008053	mitochondrial fusion

0.80	GO:0008307	structural constituent of muscle
0.75	GO:0051015	actin filament binding

0.66	GO:0030018	Z disc
0.33	GO:0005925	focal adhesion
0.33	GO:0005856	cytoskeleton

sp|Q0ZLH3|PJVK_HUMAN
Pejvakin
Search

DFNB59

0.93	Deafness, autosomal recessive 59

0.82

GO:0007605

sensory perception of sound

0.81

GO:0043025

neuronal cell body

sp|Q10469|MGAT2_HUMAN
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
Search

MGAT2

0.93	Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

0.73	GO:0009312	oligosaccharide biosynthetic process
0.53	GO:0018279	protein N-linked glycosylation via asparagine

0.86	GO:0008455	alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity
0.37	GO:0030246	carbohydrate binding

0.80	GO:0005795	Golgi stack
0.38	GO:0000139	Golgi membrane
0.30	GO:0031224	intrinsic component of membrane

0.86

EC:2.4.1.143

GO:0008455

sp|Q10471|GALT2_HUMAN
Polypeptide N-acetylgalactosaminyltransferase 2
Search

GALNT2

0.64	Polypeptide N-acetylgalactosaminyltransferase

0.72	GO:0006486	protein glycosylation
0.58	GO:0002378	immunoglobulin biosynthetic process
0.53	GO:0018210	peptidyl-threonine modification
0.52	GO:0018209	peptidyl-serine modification

0.68	GO:0030246	carbohydrate binding
0.64	GO:0016757	transferase activity, transferring glycosyl groups
0.48	GO:0030145	manganese ion binding
0.42	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0005515	protein binding

0.72	GO:0000139	Golgi membrane
0.51	GO:0005795	Golgi stack
0.51	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.35	GO:0005796	Golgi lumen
0.34	GO:0031301	integral component of organelle membrane
0.34	GO:0005789	endoplasmic reticulum membrane

0.64

EC:2.4

GO:0016757

sp|Q10472|GALT1_HUMAN
Polypeptide N-acetylgalactosaminyltransferase 1
Search

GALNT1

0.64	Polypeptide N-acetylgalactosaminyltransferase

0.73	GO:0043413	macromolecule glycosylation
0.73	GO:0009101	glycoprotein biosynthetic process
0.59	GO:0036211	protein modification process
0.55	GO:0044267	cellular protein metabolic process

0.69	GO:0030246	carbohydrate binding
0.64	GO:0016757	transferase activity, transferring glycosyl groups
0.49	GO:0030145	manganese ion binding
0.45	GO:0140096	catalytic activity, acting on a protein

0.73	GO:0000139	Golgi membrane
0.51	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0031985	Golgi cisterna
0.37	GO:0005576	extracellular region
0.34	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.64

EC:2.4

GO:0016757

sp|Q10567|AP1B1_HUMAN
AP-1 complex subunit beta-1
Search

AP1B1

0.64	AP complex subunit beta

0.69	GO:0006886	intracellular protein transport
0.68	GO:0016192	vesicle-mediated transport
0.51	GO:0007368	determination of left/right symmetry
0.50	GO:0048513	animal organ development
0.49	GO:0072359	circulatory system development
0.44	GO:0048882	lateral line development
0.44	GO:0050974	detection of mechanical stimulus involved in sensory perception
0.44	GO:2000649	regulation of sodium ion transmembrane transporter activity
0.44	GO:0035315	hair cell differentiation
0.43	GO:1903076	regulation of protein localization to plasma membrane

0.79	GO:0030276	clathrin binding
0.49	GO:0019901	protein kinase binding
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0005215	transporter activity
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.77	GO:0030131	clathrin adaptor complex
0.47	GO:0005794	Golgi apparatus
0.46	GO:0005829	cytosol
0.37	GO:0030665	clathrin-coated vesicle membrane
0.35	GO:0031984	organelle subcompartment
0.34	GO:0005765	lysosomal membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q10570|CPSF1_HUMAN
Cleavage and polyadenylation specificity factor subunit 1
Search

CPSF1

0.91	Cleavage and polyadenylation specificity factor subunit 1

0.59	GO:0006378	mRNA polyadenylation
0.50	GO:0060216	definitive hemopoiesis
0.48	GO:0006379	mRNA cleavage
0.36	GO:0006369	termination of RNA polymerase II transcription
0.36	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation
0.36	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.35	GO:0051028	mRNA transport
0.35	GO:0000398	mRNA splicing, via spliceosome
0.35	GO:0006405	RNA export from nucleus

0.58	GO:0035925	mRNA 3'-UTR AU-rich region binding
0.49	GO:0019899	enzyme binding

0.60	GO:0005634	nucleus
0.48	GO:0031974	membrane-enclosed lumen
0.44	GO:0043234	protein complex
0.43	GO:0044446	intracellular organelle part

sp|Q10571|MN1_HUMAN
Transcriptional activator MN1
Search

MN1

0.97	MN1 proto-oncogene, transcriptional regulator

0.73	GO:0036072	direct ossification
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.42	GO:0007275	multicellular organism development
0.38	GO:0097659	nucleic acid-templated transcription
0.37	GO:0010467	gene expression
0.37	GO:0034645	cellular macromolecule biosynthetic process
0.37	GO:0015914	phospholipid transport

0.37

GO:0005548

phospholipid transporter activity

0.32	GO:0005622	intracellular
0.30	GO:0031224	intrinsic component of membrane

sp|Q10586|DBP_HUMAN
D site-binding protein
Search

0.92	D-box binding PAR bZIP transcription factor

0.72	GO:0007623	circadian rhythm
0.71	GO:0006366	transcription by RNA polymerase II
0.71	GO:0045944	positive regulation of transcription by RNA polymerase II
0.60	GO:0035914	skeletal muscle cell differentiation

0.76	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.71	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.69	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding

0.61

GO:0005634

nucleus

sp|Q10587|TEF_HUMAN
Thyrotroph embryonic factor
Search

TEF

0.96	Thyrotrophic embryonic factor

0.70	GO:0006357	regulation of transcription by RNA polymerase II
0.52	GO:0045893	positive regulation of transcription, DNA-templated
0.45	GO:0006366	transcription by RNA polymerase II
0.43	GO:0007275	multicellular organism development
0.40	GO:0071482	cellular response to light stimulus
0.39	GO:0048511	rhythmic process

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.50	GO:0003690	double-stranded DNA binding
0.46	GO:0001012	RNA polymerase II regulatory region DNA binding
0.34	GO:0005515	protein binding

0.61

GO:0005634

nucleus

sp|Q10588|BST1_HUMAN
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2
Search

BST1

0.97	Bone marrow stromal cell antigen 1

0.76	GO:0090022	regulation of neutrophil chemotaxis
0.74	GO:0050848	regulation of calcium-mediated signaling
0.73	GO:0001952	regulation of cell-matrix adhesion
0.71	GO:0050730	regulation of peptidyl-tyrosine phosphorylation
0.70	GO:0050727	regulation of inflammatory response
0.69	GO:0008284	positive regulation of cell proliferation
0.67	GO:0032956	regulation of actin cytoskeleton organization
0.57	GO:0030888	regulation of B cell proliferation
0.56	GO:0050871	positive regulation of B cell activation

0.86	GO:0003953	NAD+ nucleosidase activity
0.82	GO:0061811	ADP-ribosyl cyclase activity
0.82	GO:0061812	cyclic ADP-ribose hydrolase
0.51	GO:0016849	phosphorus-oxygen lyase activity

0.77	GO:0001931	uropod
0.70	GO:0008305	integrin complex
0.65	GO:0019898	extrinsic component of membrane

0.51

EC:4.6

GO:0016849

sp|Q10589|BST2_HUMAN
Bone marrow stromal antigen 2
Search

BST2

0.97	Bone marrow stromal cell antigen 2

0.78	GO:0051607	defense response to virus
0.52	GO:0002737	negative regulation of plasmacytoid dendritic cell cytokine production
0.51	GO:1901253	negative regulation of intracellular transport of viral material
0.48	GO:0045071	negative regulation of viral genome replication
0.47	GO:0030308	negative regulation of cell growth
0.47	GO:0030336	negative regulation of cell migration
0.46	GO:0045087	innate immune response
0.45	GO:0010951	negative regulation of endopeptidase activity
0.40	GO:0035455	response to interferon-alpha
0.40	GO:0035456	response to interferon-beta

0.48	GO:0008191	metalloendopeptidase inhibitor activity
0.44	GO:0042803	protein homodimerization activity
0.35	GO:0004871	signal transducer activity
0.34	GO:0003723	RNA binding

0.47	GO:0005771	multivesicular body
0.45	GO:0009986	cell surface
0.44	GO:0005794	Golgi apparatus
0.43	GO:0005829	cytosol
0.39	GO:0005886	plasma membrane
0.39	GO:0035577	azurophil granule membrane
0.38	GO:0045121	membrane raft
0.38	GO:0045177	apical part of cell
0.38	GO:0031225	anchored component of membrane
0.37	GO:0070062	extracellular exosome

sp|Q10713|MPPA_HUMAN
Mitochondrial-processing peptidase subunit alpha
Search

PMPCA

0.88	Mitochondrial-processing peptidase subunit alpha

0.80	GO:0006627	protein processing involved in protein targeting to mitochondrion
0.36	GO:0006851	mitochondrial calcium ion transmembrane transport

0.64	GO:0004222	metalloendopeptidase activity
0.52	GO:0046872	metal ion binding

0.59	GO:0005739	mitochondrion
0.47	GO:0019866	organelle inner membrane
0.37	GO:0031974	membrane-enclosed lumen
0.36	GO:0005615	extracellular space

0.64

GO:0004222

sp|Q107X0|KRIP1_HUMAN
Putative protein KRIP1
Search

sp|Q10981|FUT2_HUMAN
Galactoside 2-alpha-L-fucosyltransferase 2
Search

FUT2

0.83	L-Fucosyltransferase

0.81	GO:0036065	fucosylation
0.74	GO:0043413	macromolecule glycosylation
0.74	GO:0009101	glycoprotein biosynthetic process
0.60	GO:0005975	carbohydrate metabolic process
0.60	GO:0036211	protein modification process
0.55	GO:0044267	cellular protein metabolic process
0.34	GO:0044282	small molecule catabolic process
0.34	GO:1901575	organic substance catabolic process
0.32	GO:0016310	phosphorylation

0.84	GO:0008107	galactoside 2-alpha-L-fucosyltransferase activity
0.34	GO:0003951	NAD+ kinase activity

0.81	GO:0032580	Golgi cisterna membrane
0.36	GO:0070062	extracellular exosome
0.33	GO:0005887	integral component of plasma membrane

0.84	EC:2.4.1.69	GO:0008107
0.34	KEGG:R00104	GO:0003951

sp|Q11128|FUT5_HUMAN
Alpha-(1,3)-fucosyltransferase 5
Search

0.63	Lewis alpha-3-fucosyltransferase

0.81	GO:0036065	fucosylation
0.74	GO:0006486	protein glycosylation
0.44	GO:0006672	ceramide metabolic process
0.40	GO:0042355	L-fucose catabolic process
0.38	GO:0009312	oligosaccharide biosynthetic process
0.36	GO:0009988	cell-cell recognition

0.81	GO:0008417	fucosyltransferase activity
0.33	GO:0005509	calcium ion binding

0.81	GO:0032580	Golgi cisterna membrane
0.40	GO:0009986	cell surface
0.37	GO:0070062	extracellular exosome
0.35	GO:0071944	cell periphery
0.30	GO:0031224	intrinsic component of membrane

0.81

GO:0008417

sp|Q11130|FUT7_HUMAN
Alpha-(1,3)-fucosyltransferase 7
Search

FUT7

0.74	Fucosyltransferase 7 variant 4

0.81	GO:0036065	fucosylation
0.74	GO:0043413	macromolecule glycosylation
0.74	GO:0009101	glycoprotein biosynthetic process
0.60	GO:0036211	protein modification process
0.58	GO:0002522	leukocyte migration involved in immune response
0.57	GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
0.56	GO:0044267	cellular protein metabolic process
0.53	GO:0006672	ceramide metabolic process
0.36	GO:0042355	L-fucose catabolic process

0.81	GO:0008417	fucosyltransferase activity
0.33	GO:0005509	calcium ion binding

0.81	GO:0032580	Golgi cisterna membrane
0.38	GO:0009986	cell surface
0.35	GO:0071944	cell periphery
0.30	GO:0016021	integral component of membrane

0.81

GO:0008417

sp|Q11201|SIA4A_HUMAN
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1
Search

ST3GAL1

0.93	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2

0.83	GO:0097503	sialylation
0.74	GO:0043413	macromolecule glycosylation
0.74	GO:0009101	glycoprotein biosynthetic process
0.60	GO:0036211	protein modification process
0.56	GO:0044267	cellular protein metabolic process
0.50	GO:0009311	oligosaccharide metabolic process
0.47	GO:0030259	lipid glycosylation
0.45	GO:0009247	glycolipid biosynthetic process
0.43	GO:0016310	phosphorylation
0.43	GO:0016051	carbohydrate biosynthetic process

0.83

GO:0008373

sialyltransferase activity

0.69	GO:0005794	Golgi apparatus
0.46	GO:0098588	bounding membrane of organelle
0.45	GO:0031984	organelle subcompartment
0.39	GO:0005576	extracellular region
0.36	GO:0031982	vesicle
0.30	GO:0031224	intrinsic component of membrane

0.83

EC:2.4.99

GO:0008373

sp|Q11203|SIAT6_HUMAN
CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase
Search

ST3GAL3

0.92	CMP-N-acetylneuraminate-beta-1,4-galactoside

0.83	GO:0097503	sialylation
0.74	GO:0043413	macromolecule glycosylation
0.74	GO:0009101	glycoprotein biosynthetic process
0.60	GO:0006464	cellular protein modification process
0.42	GO:0009311	oligosaccharide metabolic process
0.36	GO:0018146	keratan sulfate biosynthetic process

0.83

GO:0008373

sialyltransferase activity

0.69	GO:0005794	Golgi apparatus
0.41	GO:0098588	bounding membrane of organelle
0.41	GO:0031984	organelle subcompartment
0.36	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.83

EC:2.4.99

GO:0008373

sp|Q11206|SIA4C_HUMAN
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4
Search

ST3GAL4

0.91	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2

0.83	GO:0097503	sialylation
0.74	GO:0006486	protein glycosylation
0.54	GO:0050890	cognition
0.52	GO:0030259	lipid glycosylation
0.50	GO:0009311	oligosaccharide metabolic process
0.50	GO:0009247	glycolipid biosynthetic process
0.47	GO:0016051	carbohydrate biosynthetic process
0.46	GO:0018196	peptidyl-asparagine modification
0.36	GO:0018146	keratan sulfate biosynthetic process

0.83	GO:0008373	sialyltransferase activity
0.33	GO:0005515	protein binding

0.68	GO:0005794	Golgi apparatus
0.42	GO:0098588	bounding membrane of organelle
0.41	GO:0031984	organelle subcompartment
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.83

EC:2.4.99

GO:0008373

sp|Q12756|KIF1A_HUMAN
Kinesin-like protein KIF1A
Search

KIF1A

0.95	Kinesin family member 1Aa

0.74	GO:0007018	microtubule-based movement
0.47	GO:0030705	cytoskeleton-dependent intracellular transport
0.39	GO:0022027	interkinetic nuclear migration
0.36	GO:0006886	intracellular protein transport

0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0042802	identical protein binding
0.40	GO:0016887	ATPase activity
0.36	GO:0046983	protein dimerization activity

0.47	GO:0005871	kinesin complex
0.38	GO:1904115	axon cytoplasm
0.37	GO:0008021	synaptic vesicle
0.37	GO:0043025	neuronal cell body
0.37	GO:0030425	dendrite
0.37	GO:0098794	postsynapse
0.36	GO:0005874	microtubule
0.36	GO:0005829	cytosol

0.40

GO:0016887

sp|Q12765|SCRN1_HUMAN
Secernin-1
Search

SCRN1

0.97	Secernin-1 isoform a

0.61	GO:0006508	proteolysis
0.47	GO:0006887	exocytosis
0.32	GO:0000413	protein peptidyl-prolyl isomerization

0.77	GO:0016805	dipeptidase activity
0.33	GO:0005515	protein binding
0.32	GO:0003755	peptidyl-prolyl cis-trans isomerase activity

0.52	GO:0031965	nuclear membrane
0.34	GO:0005737	cytoplasm

0.77

EC:3.4.13

GO:0016805

sp|Q12766|HMGX3_HUMAN
HMG domain-containing protein 3
Search

HMGXB3

0.96	HMG-box containing 3

0.55

GO:0003677

DNA binding

0.61

GO:0005634

nucleus

sp|Q12767|TMM94_HUMAN
Transmembrane protein 94
Search

TMEM94

0.97	Transmembrane protein 94

0.33	GO:1901265	nucleoside phosphate binding
0.33	GO:0036094	small molecule binding

0.30

GO:0044425

membrane part

sp|Q12768|WASC5_HUMAN
WASH complex subunit 5
Search

WASHC5

0.95	WASH complex subunit strumpellin

0.57	GO:0040038	polar body extrusion after meiotic divisions
0.55	GO:0090306	spindle assembly involved in meiosis
0.55	GO:0001556	oocyte maturation
0.51	GO:0016197	endosomal transport
0.37	GO:0048699	generation of neurons
0.37	GO:0015031	protein transport
0.37	GO:0031346	positive regulation of cell projection organization
0.37	GO:0010720	positive regulation of cell development
0.37	GO:0051962	positive regulation of nervous system development
0.37	GO:0120035	regulation of plasma membrane bounded cell projection organization

0.33	GO:0005515	protein binding
0.33	GO:0008270	zinc ion binding
0.32	GO:0003735	structural constituent of ribosome

0.81	GO:0071203	WASH complex
0.53	GO:0005769	early endosome
0.48	GO:0005654	nucleoplasm
0.37	GO:0043025	neuronal cell body
0.36	GO:0005783	endoplasmic reticulum
0.36	GO:0043005	neuron projection
0.36	GO:0005829	cytosol
0.32	GO:0015934	large ribosomal subunit
0.30	GO:0031224	intrinsic component of membrane

sp|Q12769|NU160_HUMAN
Nuclear pore complex protein Nup160
Search

NUP160

0.96	Nuclear pore complex protein Nup160

0.78	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.74	GO:0051028	mRNA transport
0.73	GO:0006405	RNA export from nucleus
0.52	GO:0010467	gene expression
0.42	GO:0007077	mitotic nuclear envelope disassembly
0.41	GO:1900034	regulation of cellular response to heat
0.41	GO:0071431	tRNA-containing ribonucleoprotein complex export from nucleus
0.41	GO:0006110	regulation of glycolytic process
0.41	GO:0051031	tRNA transport
0.40	GO:0060964	regulation of gene silencing by miRNA

0.79	GO:0005487	structural constituent of nuclear pore
0.36	GO:0005515	protein binding
0.36	GO:0004960	thromboxane receptor activity

0.82	GO:0031080	nuclear pore outer ring
0.76	GO:0000776	kinetochore
0.37	GO:0005829	cytosol
0.36	GO:0044217	other organism part
0.36	GO:0018995	host
0.30	GO:0016020	membrane

sp|Q12770|SCAP_HUMAN
Sterol regulatory element-binding protein cleavage-activating protein
Search

SCAP

0.95	SREBF chaperone

0.85	GO:0032933	SREBP signaling pathway
0.83	GO:0008203	cholesterol metabolic process
0.70	GO:0045540	regulation of cholesterol biosynthetic process
0.65	GO:0042304	regulation of fatty acid biosynthetic process
0.65	GO:0032868	response to insulin
0.64	GO:0001666	response to hypoxia
0.47	GO:0019915	lipid storage

0.84	GO:0015485	cholesterol binding
0.30	GO:0003824	catalytic activity

0.74	GO:0000139	Golgi membrane
0.72	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q12772|SRBP2_HUMAN
Sterol regulatory element-binding protein 2
Search

SREBF2

0.96	Sterol regulatory element binding transcription factor 2

0.60	GO:0090370	negative regulation of cholesterol efflux
0.59	GO:0072368	regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter
0.59	GO:0010886	positive regulation of cholesterol storage
0.58	GO:2000188	regulation of cholesterol homeostasis
0.58	GO:0071404	cellular response to low-density lipoprotein particle stimulus
0.57	GO:1903146	regulation of autophagy of mitochondrion
0.56	GO:1903955	positive regulation of protein targeting to mitochondrion
0.53	GO:0009267	cellular response to starvation
0.52	GO:0045944	positive regulation of transcription by RNA polymerase II
0.42	GO:0008203	cholesterol metabolic process

0.67	GO:0046983	protein dimerization activity
0.57	GO:0070888	E-box binding
0.55	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.55	GO:0008022	protein C-terminus binding
0.39	GO:0000247	C-8 sterol isomerase activity
0.35	GO:0003682	chromatin binding

0.59	GO:0032937	SREBP-SCAP-Insig complex
0.49	GO:0005654	nucleoplasm
0.45	GO:0005739	mitochondrion
0.41	GO:0012507	ER to Golgi transport vesicle membrane
0.40	GO:0000139	Golgi membrane
0.35	GO:0030425	dendrite
0.34	GO:0005829	cytosol

0.39

EC:5.3.3

GO:0000247

sp|Q12774|ARHG5_HUMAN
Rho guanine nucleotide exchange factor 5
Search

ARHGEF5

0.95	Rho guanine nucleotide exchange factor 5

0.76	GO:0035023	regulation of Rho protein signal transduction
0.65	GO:0065009	regulation of molecular function
0.64	GO:0002408	myeloid dendritic cell chemotaxis
0.62	GO:0071803	positive regulation of podosome assembly
0.61	GO:0051496	positive regulation of stress fiber assembly
0.60	GO:1904591	positive regulation of protein import
0.60	GO:0046330	positive regulation of JNK cascade
0.58	GO:0035556	intracellular signal transduction
0.53	GO:0030036	actin cytoskeleton organization
0.45	GO:1903506	regulation of nucleic acid-templated transcription

0.77	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.39	GO:0008289	lipid binding
0.36	GO:0032550	purine ribonucleoside binding
0.36	GO:0019001	guanyl nucleotide binding
0.34	GO:0005096	GTPase activator activity
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.52	GO:0005654	nucleoplasm
0.51	GO:0005829	cytosol
0.44	GO:0005886	plasma membrane
0.42	GO:0002102	podosome
0.39	GO:0030054	cell junction
0.38	GO:0042995	cell projection

sp|Q12778|FOXO1_HUMAN
Forkhead box protein O1
Search

FOXO1

0.97	Forkhead protein FKHR

0.63	GO:0071455	cellular response to hyperoxia
0.59	GO:0032873	negative regulation of stress-activated MAPK cascade
0.57	GO:0045732	positive regulation of protein catabolic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:0010508	positive regulation of autophagy
0.56	GO:0043065	positive regulation of apoptotic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0009267	cellular response to starvation
0.55	GO:0071732	cellular response to nitric oxide

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.58	GO:0008013	beta-catenin binding
0.55	GO:0031625	ubiquitin protein ligase binding
0.55	GO:0051721	protein phosphatase 2A binding
0.48	GO:0000989	transcription factor activity, transcription factor binding
0.47	GO:0008134	transcription factor binding
0.39	GO:0003682	chromatin binding
0.33	GO:0042802	identical protein binding
0.33	GO:0001047	core promoter binding

0.61	GO:0005634	nucleus
0.41	GO:0005737	cytoplasm
0.36	GO:0070013	intracellular organelle lumen
0.35	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|Q12788|TBL3_HUMAN
Transducin beta-like protein 3
Search

TBL3

0.88	WD repeat-containing protein 65

0.68	GO:0006364	rRNA processing
0.49	GO:0048538	thymus development
0.47	GO:0030098	lymphocyte differentiation
0.45	GO:0010564	regulation of cell cycle process
0.43	GO:0042274	ribosomal small subunit biogenesis

0.46	GO:0030515	snoRNA binding
0.30	GO:0005515	protein binding
0.30	GO:0003824	catalytic activity

0.79	GO:0032040	small-subunit processome
0.48	GO:0005730	nucleolus
0.45	GO:0030686	90S preribosome
0.39	GO:0043234	protein complex
0.30	GO:0016020	membrane
0.30	GO:0005654	nucleoplasm

sp|Q12789|TF3C1_HUMAN
General transcription factor 3C polypeptide 1
Search

GTF3C1

0.95	Transcription factor IIIC subunit alpha

0.70	GO:0042791	5S class rRNA transcription by RNA polymerase III
0.68	GO:0006384	transcription initiation from RNA polymerase III promoter
0.67	GO:0009304	tRNA transcription
0.65	GO:0006359	regulation of transcription by RNA polymerase III

0.70	GO:0001003	RNA polymerase III type 2 promoter sequence-specific DNA binding
0.70	GO:0001002	RNA polymerase III type 1 promoter sequence-specific DNA binding
0.66	GO:0000995	transcription factor activity, core RNA polymerase III binding
0.66	GO:0001007	transcription factor activity, RNA polymerase III transcription factor binding
0.37	GO:0005515	protein binding

0.86	GO:0000127	transcription factor TFIIIC complex
0.71	GO:0005730	nucleolus
0.59	GO:0030529	intracellular ribonucleoprotein complex
0.39	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q12791|KCMA1_HUMAN
Calcium-activated potassium channel subunit alpha-1
Search

KCNMA1

0.82	Calcium-activated potassium channel subunit alpha-1

0.73	GO:0071805	potassium ion transmembrane transport
0.58	GO:0034465	response to carbon monoxide
0.57	GO:0060083	smooth muscle contraction involved in micturition
0.56	GO:0045794	negative regulation of cell volume
0.54	GO:0030007	cellular potassium ion homeostasis
0.53	GO:0051592	response to calcium ion
0.52	GO:0001666	response to hypoxia
0.51	GO:0006970	response to osmotic stress
0.51	GO:0043065	positive regulation of apoptotic process
0.50	GO:0042391	regulation of membrane potential

0.85	GO:0060072	large conductance calcium-activated potassium channel activity
0.77	GO:0005249	voltage-gated potassium channel activity
0.48	GO:0003779	actin binding
0.38	GO:0042802	identical protein binding
0.34	GO:0046872	metal ion binding
0.34	GO:0032403	protein complex binding
0.34	GO:0046983	protein dimerization activity

0.77	GO:0008076	voltage-gated potassium channel complex
0.53	GO:0005901	caveola
0.53	GO:0016324	apical plasma membrane
0.38	GO:0070062	extracellular exosome
0.37	GO:0043195	terminal bouton
0.37	GO:0009897	external side of plasma membrane
0.36	GO:0045211	postsynaptic membrane
0.36	GO:0048787	presynaptic active zone membrane
0.35	GO:0005783	endoplasmic reticulum
0.35	GO:0043025	neuronal cell body

sp|Q12792|TWF1_HUMAN
Twinfilin-1
Search

TWF1

0.94	Twinfilin actin binding protein 1

0.81	GO:0030837	negative regulation of actin filament polymerization
0.58	GO:0043538	regulation of actin phosphorylation
0.55	GO:0014742	positive regulation of muscle hypertrophy
0.54	GO:0010611	regulation of cardiac muscle hypertrophy
0.52	GO:0030835	negative regulation of actin filament depolymerization
0.51	GO:0032507	maintenance of protein location in cell
0.49	GO:0018108	peptidyl-tyrosine phosphorylation
0.36	GO:0010592	positive regulation of lamellipodium assembly
0.36	GO:0045773	positive regulation of axon extension
0.36	GO:0071300	cellular response to retinoic acid

0.74	GO:0003779	actin binding
0.54	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.52	GO:0045296	cadherin binding
0.50	GO:0004713	protein tyrosine kinase activity
0.49	GO:0032403	protein complex binding
0.41	GO:0032559	adenyl ribonucleotide binding
0.40	GO:0008144	drug binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0005080	protein kinase C binding
0.33	GO:0005092	GDP-dissociation inhibitor activity

0.53	GO:0030175	filopodium
0.53	GO:0032587	ruffle membrane
0.51	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0030016	myofibril
0.49	GO:0005911	cell-cell junction
0.48	GO:0015629	actin cytoskeleton
0.46	GO:0005829	cytosol
0.37	GO:0072357	PTW/PP1 phosphatase complex
0.37	GO:0048188	Set1C/COMPASS complex
0.36	GO:0005925	focal adhesion

0.50

EC:2.7.10

GO:0004713

sp|Q12794|HYAL1_HUMAN
Hyaluronidase-1
Search

HYAL1

0.71	Hyaluronidase

0.68	GO:0030214	hyaluronan catabolic process
0.66	GO:0071493	cellular response to UV-B
0.63	GO:1900104	regulation of hyaluranon cable assembly
0.63	GO:0071347	cellular response to interleukin-1
0.61	GO:0051216	cartilage development
0.61	GO:0036120	cellular response to platelet-derived growth factor stimulus
0.61	GO:0030308	negative regulation of cell growth
0.61	GO:0030213	hyaluronan biosynthetic process
0.61	GO:0060272	embryonic skeletal joint morphogenesis
0.60	GO:0071356	cellular response to tumor necrosis factor

0.85	GO:0004415	hyalurononglucosaminidase activity
0.59	GO:0050501	hyaluronan synthase activity
0.57	GO:0001618	virus receptor activity
0.52	GO:0008134	transcription factor binding
0.48	GO:0033906	hyaluronoglucuronidase activity
0.47	GO:0030294	receptor signaling protein tyrosine kinase inhibitor activity
0.44	GO:0050431	transforming growth factor beta binding
0.44	GO:0005540	hyaluronic acid binding
0.44	GO:0001105	RNA polymerase II transcription coactivator activity
0.43	GO:0030971	receptor tyrosine kinase binding

0.63	GO:0036117	hyaluranon cable
0.59	GO:0005764	lysosome
0.55	GO:0031410	cytoplasmic vesicle
0.53	GO:0005615	extracellular space
0.44	GO:0005902	microvillus
0.44	GO:0031362	anchored component of external side of plasma membrane
0.43	GO:0016324	apical plasma membrane
0.43	GO:0098857	membrane microdomain
0.43	GO:0048471	perinuclear region of cytoplasm
0.41	GO:0090575	RNA polymerase II transcription factor complex

0.85

EC:3.2.1.35

GO:0004415

sp|Q12796|PNRC1_HUMAN
Proline-rich nuclear receptor coactivator 1
Search

PNRC1

0.88	Proline-rich nuclear receptor coactivator 1

0.82	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.71	GO:0031087	deadenylation-independent decapping of nuclear-transcribed mRNA
0.40	GO:0006351	transcription, DNA-templated
0.40	GO:2001141	regulation of RNA biosynthetic process
0.40	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.38

GO:0005515

protein binding

0.70	GO:0000932	P-body
0.54	GO:0005634	nucleus
0.46	GO:0005794	Golgi apparatus
0.44	GO:0043233	organelle lumen
0.41	GO:0044446	intracellular organelle part
0.34	GO:0005829	cytosol

sp|Q12797|ASPH_HUMAN
Aspartyl/asparaginyl beta-hydroxylase
Search

ASPH

0.71	Aspartate beta-hydroxylase

0.65	GO:0018193	peptidyl-amino acid modification
0.51	GO:0097202	activation of cysteine-type endopeptidase activity
0.46	GO:0060325	face morphogenesis
0.45	GO:0060021	palate development
0.45	GO:0018126	protein hydroxylation
0.45	GO:0035108	limb morphogenesis
0.44	GO:1901879	regulation of protein depolymerization
0.43	GO:0008285	negative regulation of cell proliferation
0.43	GO:0031647	regulation of protein stability
0.43	GO:0007389	pattern specification process

0.40	GO:0004597	peptide-aspartate beta-dioxygenase activity
0.37	GO:0005509	calcium ion binding
0.36	GO:0008307	structural constituent of muscle
0.36	GO:0044325	ion channel binding
0.34	GO:0009055	electron transfer activity

0.50	GO:0032541	cortical endoplasmic reticulum
0.39	GO:0005886	plasma membrane
0.38	GO:0030176	integral component of endoplasmic reticulum membrane
0.38	GO:0033017	sarcoplasmic reticulum membrane
0.37	GO:0033018	sarcoplasmic reticulum lumen
0.36	GO:0034704	calcium channel complex

0.40

EC:1.14.11.16

GO:0004597

sp|Q12798|CETN1_HUMAN
Centrin-1
Search

CETN1

0.89	Testicular tissue protein Li 37

0.46	GO:0007099	centriole replication
0.44	GO:0032465	regulation of cytokinesis
0.43	GO:0033554	cellular response to stress
0.42	GO:0007283	spermatogenesis
0.41	GO:0009408	response to heat
0.39	GO:0006259	DNA metabolic process
0.38	GO:0051301	cell division
0.35	GO:0055114	oxidation-reduction process
0.35	GO:0097711	ciliary basal body-plasma membrane docking
0.34	GO:0000086	G2/M transition of mitotic cell cycle

0.70	GO:0005509	calcium ion binding
0.52	GO:0032795	heterotrimeric G-protein binding
0.48	GO:0031683	G-protein beta/gamma-subunit complex binding
0.45	GO:0008017	microtubule binding
0.43	GO:0016174	NAD(P)H oxidase activity
0.33	GO:0004386	helicase activity

0.55	GO:0005814	centriole
0.52	GO:0005813	centrosome
0.49	GO:0032391	photoreceptor connecting cilium
0.48	GO:0000922	spindle pole
0.48	GO:0071942	XPC complex
0.44	GO:0036064	ciliary basal body
0.34	GO:0030008	TRAPP complex
0.33	GO:0005654	nucleoplasm
0.33	GO:0005829	cytosol

0.43

EC:1.6.3.1

GO:0016174

sp|Q12799|TCP10_HUMAN
T-complex protein 10A homolog
Search

0.97	T-complex 10 like

0.66	GO:0000122	negative regulation of transcription by RNA polymerase II
0.44	GO:0048858	cell projection morphogenesis
0.44	GO:0006351	transcription, DNA-templated

0.73	GO:0001106	RNA polymerase II transcription corepressor activity
0.72	GO:0070491	repressing transcription factor binding
0.72	GO:0043621	protein self-association
0.63	GO:0042802	identical protein binding

0.56	GO:0005634	nucleus
0.50	GO:0005829	cytosol

sp|Q12800|TFCP2_HUMAN
Alpha-globin transcription factor CP2
Search

TFCP2

0.77	Transcription factor LSF

0.70	GO:0006366	transcription by RNA polymerase II
0.69	GO:0045944	positive regulation of transcription by RNA polymerase II
0.56	GO:0009299	mRNA transcription
0.41	GO:0002070	epithelial cell maturation
0.41	GO:0007028	cytoplasm organization
0.41	GO:0007431	salivary gland development
0.40	GO:0008340	determination of adult lifespan
0.40	GO:0045927	positive regulation of growth
0.39	GO:0000122	negative regulation of transcription by RNA polymerase II
0.39	GO:0000902	cell morphogenesis

0.75	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.53	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.52	GO:0000987	proximal promoter sequence-specific DNA binding
0.49	GO:0008134	transcription factor binding
0.39	GO:0008022	protein C-terminus binding
0.34	GO:0003714	transcription corepressor activity

0.49	GO:0031981	nuclear lumen
0.47	GO:0005829	cytosol
0.43	GO:0043234	protein complex
0.36	GO:0005739	mitochondrion
0.36	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

sp|Q12802|AKP13_HUMAN
A-kinase anchor protein 13
Search

AKAP13

0.77	A-kinase anchoring protein 13

0.78	GO:0035023	regulation of Rho protein signal transduction
0.65	GO:0065009	regulation of molecular function
0.63	GO:0006468	protein phosphorylation
0.60	GO:0035556	intracellular signal transduction
0.55	GO:0071875	adrenergic receptor signaling pathway
0.54	GO:0046579	positive regulation of Ras protein signal transduction
0.54	GO:1900169	regulation of glucocorticoid mediated signaling pathway
0.53	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.53	GO:0086103	G-protein coupled receptor signaling pathway involved in heart process
0.52	GO:0060297	regulation of sarcomere organization

0.85	GO:0004691	cAMP-dependent protein kinase activity
0.76	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.56	GO:0005078	MAP-kinase scaffold activity
0.54	GO:0051018	protein kinase A binding
0.48	GO:0046872	metal ion binding
0.35	GO:0004871	signal transducer activity

0.52	GO:0030864	cortical actin cytoskeleton
0.49	GO:0005884	actin filament
0.47	GO:0005829	cytosol
0.39	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.85

EC:2.7.11.11

GO:0004691

sp|Q12805|FBLN3_HUMAN
EGF-containing fibulin-like extracellular matrix protein 1
Search

EFEMP1

0.97	EGF containing fibulin like extracellular matrix protein 1

0.84	GO:0007173	epidermal growth factor receptor signaling pathway
0.63	GO:0048050	post-embryonic eye morphogenesis
0.62	GO:0032331	negative regulation of chondrocyte differentiation
0.60	GO:0048048	embryonic eye morphogenesis
0.57	GO:0043010	camera-type eye development
0.55	GO:0018108	peptidyl-tyrosine phosphorylation
0.46	GO:0048251	elastic fiber assembly
0.45	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.45	GO:1903506	regulation of nucleic acid-templated transcription
0.44	GO:0010468	regulation of gene expression

0.86	GO:0005006	epidermal growth factor-activated receptor activity
0.70	GO:0005509	calcium ion binding
0.61	GO:0005154	epidermal growth factor receptor binding
0.40	GO:0008083	growth factor activity

0.73	GO:0031012	extracellular matrix
0.56	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.32	GO:0005737	cytoplasm

sp|Q12809|KCNH2_HUMAN
Potassium voltage-gated channel subfamily H member 2
Search

KCNH2

0.57	Potassium voltage-gated channel subfamily H member 2

0.75	GO:0034765	regulation of ion transmembrane transport
0.71	GO:0071805	potassium ion transmembrane transport
0.59	GO:0086091	regulation of heart rate by cardiac conduction
0.58	GO:0099625	ventricular cardiac muscle cell membrane repolarization
0.58	GO:0086013	membrane repolarization during cardiac muscle cell action potential
0.57	GO:0086005	ventricular cardiac muscle cell action potential
0.57	GO:0043267	negative regulation of potassium ion transport
0.56	GO:0086010	membrane depolarization during action potential
0.55	GO:0043268	positive regulation of potassium ion transport
0.55	GO:0055075	potassium ion homeostasis

0.76	GO:0005249	voltage-gated potassium channel activity
0.59	GO:0055131	C3HC4-type RING finger domain binding
0.56	GO:0097110	scaffold protein binding
0.54	GO:0000155	phosphorelay sensor kinase activity
0.54	GO:0099094	ligand-gated cation channel activity
0.53	GO:0031625	ubiquitin protein ligase binding
0.51	GO:0042803	protein homodimerization activity
0.34	GO:0008237	metallopeptidase activity

0.59	GO:1902937	inward rectifier potassium channel complex
0.52	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0009986	cell surface
0.37	GO:0005635	nuclear envelope

0.54

EC:2.7.3

GO:0000155

sp|Q12815|TROAP_HUMAN
Tastin
Search

TROAP

0.63

tastin

0.30

GO:0022610

biological adhesion

0.30

GO:0005488

binding

0.30

GO:0005737

cytoplasm

sp|Q12816|TROP_HUMAN
Trophinin
Search

TRO

0.94

Trophinin

0.71	GO:0032922	circadian regulation of gene expression
0.62	GO:0042981	regulation of apoptotic process
0.61	GO:0070294	renal sodium ion absorption
0.58	GO:0007565	female pregnancy
0.54	GO:0050680	negative regulation of epithelial cell proliferation
0.53	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis
0.52	GO:0030308	negative regulation of cell growth
0.51	GO:0042752	regulation of circadian rhythm
0.50	GO:0043406	positive regulation of MAP kinase activity
0.49	GO:0043068	positive regulation of programmed cell death

0.50	GO:0042802	identical protein binding
0.49	GO:0003713	transcription coactivator activity
0.37	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity
0.36	GO:0004705	JUN kinase activity

0.54	GO:0005634	nucleus
0.51	GO:0005829	cytosol
0.49	GO:0043233	organelle lumen
0.49	GO:0043232	intracellular non-membrane-bounded organelle
0.48	GO:0044446	intracellular organelle part
0.43	GO:0043234	protein complex
0.36	GO:0031091	platelet alpha granule
0.36	GO:0005886	plasma membrane
0.35	GO:0061695	transferase complex, transferring phosphorus-containing groups
0.34	GO:0005576	extracellular region

0.37

EC:3.1.3.46

GO:0004331

sp|Q12824|SNF5_HUMAN
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
Search

SMARCB1

0.92	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1-A

0.77	GO:0006338	chromatin remodeling
0.54	GO:0001835	blastocyst hatching
0.53	GO:0008285	negative regulation of cell proliferation
0.49	GO:0030154	cell differentiation
0.48	GO:0031498	chromatin disassembly
0.48	GO:0032986	protein-DNA complex disassembly
0.45	GO:0034728	nucleosome organization
0.43	GO:0006357	regulation of transcription by RNA polymerase II
0.41	GO:0006281	DNA repair
0.40	GO:0039692	single stranded viral RNA replication via double stranded DNA intermediate

0.39	GO:0030957	Tat protein binding
0.38	GO:0001164	RNA polymerase I CORE element sequence-specific DNA binding
0.38	GO:0002039	p53 binding
0.37	GO:0003713	transcription coactivator activity
0.37	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.37	GO:0031492	nucleosomal DNA binding
0.36	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.33	GO:0004222	metalloendopeptidase activity
0.33	GO:0008270	zinc ion binding

0.72	GO:0000228	nuclear chromosome
0.53	GO:0001650	fibrillar center
0.53	GO:0001741	XY body
0.49	GO:0097458	neuron part
0.48	GO:0000785	chromatin
0.47	GO:0005654	nucleoplasm
0.45	GO:1904949	ATPase complex
0.34	GO:0031012	extracellular matrix
0.34	GO:0043234	protein complex

0.33

GO:0004222

sp|Q12829|RB40B_HUMAN
Ras-related protein Rab-40B
Search

RAB40B

0.91	SOCS box-containing protein RAR2A

0.68	GO:0016567	protein ubiquitination
0.62	GO:0035556	intracellular signal transduction
0.49	GO:0072659	protein localization to plasma membrane
0.49	GO:0017157	regulation of exocytosis
0.48	GO:0006904	vesicle docking involved in exocytosis
0.46	GO:1990967	multi-organism toxin transport
0.44	GO:0009306	protein secretion
0.35	GO:0001881	receptor recycling
0.34	GO:0042552	myelination

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.38	GO:0019003	GDP binding

0.50	GO:0030667	secretory granule membrane
0.49	GO:0008021	synaptic vesicle
0.46	GO:0005768	endosome
0.44	GO:0048471	perinuclear region of cytoplasm
0.41	GO:0005635	nuclear envelope
0.39	GO:0005886	plasma membrane
0.35	GO:0005739	mitochondrion

sp|Q12830|BPTF_HUMAN
Nucleosome-remodeling factor subunit BPTF
Search

BPTF

0.79	Bromodomain PHD finger transcription factor

0.72	GO:0007492	endoderm development
0.71	GO:0009952	anterior/posterior pattern specification
0.70	GO:0001892	embryonic placenta development
0.68	GO:0007420	brain development
0.67	GO:0000122	negative regulation of transcription by RNA polymerase II
0.66	GO:0006338	chromatin remodeling
0.63	GO:0045893	positive regulation of transcription, DNA-templated
0.51	GO:0006351	transcription, DNA-templated
0.41	GO:0060897	neural plate regionalization
0.40	GO:0016584	nucleosome positioning

0.84	GO:0140034	methylation-dependent protein binding
0.80	GO:0042393	histone binding
0.63	GO:0008134	transcription factor binding
0.60	GO:0008094	DNA-dependent ATPase activity
0.57	GO:0043565	sequence-specific DNA binding
0.54	GO:0046872	metal ion binding
0.40	GO:0001047	core promoter binding
0.38	GO:0003690	double-stranded DNA binding
0.36	GO:0061608	nuclear import signal receptor activity
0.34	GO:0008565	protein transporter activity

0.84	GO:0016589	NURF complex
0.69	GO:0048188	Set1C/COMPASS complex
0.39	GO:0030425	dendrite
0.39	GO:0044297	cell body
0.39	GO:0048471	perinuclear region of cytoplasm
0.32	GO:0070062	extracellular exosome

sp|Q12834|CDC20_HUMAN
Cell division cycle protein 20 homolog
Search

CDC20

0.93	Cell division cycle protein 20

0.83	GO:1904668	positive regulation of ubiquitin protein ligase activity
0.83	GO:0031145	anaphase-promoting complex-dependent catabolic process
0.59	GO:0031915	positive regulation of synaptic plasticity
0.59	GO:0090129	positive regulation of synapse maturation
0.57	GO:0051301	cell division
0.55	GO:0090307	mitotic spindle assembly
0.55	GO:0040020	regulation of meiotic nuclear division
0.54	GO:0007064	mitotic sister chromatid cohesion
0.39	GO:0016567	protein ubiquitination
0.38	GO:0050773	regulation of dendrite development

0.84	GO:0097027	ubiquitin-protein transferase activator activity
0.83	GO:0010997	anaphase-promoting complex binding
0.57	GO:0008022	protein C-terminus binding
0.51	GO:0019899	enzyme binding
0.38	GO:0004896	cytokine receptor activity
0.35	GO:0061630	ubiquitin protein ligase activity
0.35	GO:0009922	fatty acid elongase activity
0.33	GO:0043531	ADP binding

0.56	GO:0005680	anaphase-promoting complex
0.50	GO:0005654	nucleoplasm
0.49	GO:0005829	cytosol
0.40	GO:0005819	spindle
0.39	GO:0005815	microtubule organizing center
0.38	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0043234	protein complex
0.35	GO:0000775	chromosome, centromeric region
0.34	GO:0005783	endoplasmic reticulum
0.30	GO:0016020	membrane

sp|Q12836|ZP4_HUMAN
Zona pellucida sperm-binding protein 4
Search

ZP4

0.97	Egg envelope component ZPB

0.62	GO:2000360	negative regulation of binding of sperm to zona pellucida
0.61	GO:0060478	acrosomal vesicle exocytosis
0.60	GO:2000344	positive regulation of acrosome reaction
0.59	GO:0002922	positive regulation of humoral immune response
0.58	GO:0042102	positive regulation of T cell proliferation
0.40	GO:0007339	binding of sperm to zona pellucida

0.61	GO:0032190	acrosin binding
0.52	GO:0042802	identical protein binding

0.61	GO:0005576	extracellular region
0.37	GO:0005886	plasma membrane
0.33	GO:0043234	protein complex
0.32	GO:0036338	viral membrane
0.30	GO:0016021	integral component of membrane

sp|Q12837|PO4F2_HUMAN
POU domain, class 4, transcription factor 2
Search

POU4F2

0.53	POU domain, class 4, transcription factor 2

0.66	GO:0007605	sensory perception of sound
0.64	GO:0031290	retinal ganglion cell axon guidance
0.64	GO:0050885	neuromuscular process controlling balance
0.64	GO:0007423	sensory organ development
0.63	GO:0048675	axon extension
0.62	GO:1902870	negative regulation of amacrine cell differentiation
0.61	GO:0090259	regulation of retinal ganglion cell axon guidance
0.61	GO:1990791	dorsal root ganglion development
0.60	GO:0045672	positive regulation of osteoclast differentiation
0.59	GO:0030520	intracellular estrogen receptor signaling pathway

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.59	GO:0001012	RNA polymerase II regulatory region DNA binding
0.58	GO:1990841	promoter-specific chromatin binding
0.56	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.56	GO:0003714	transcription corepressor activity
0.55	GO:0003690	double-stranded DNA binding
0.41	GO:0003713	transcription coactivator activity
0.38	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding
0.38	GO:0035326	enhancer binding

0.61	GO:0005634	nucleus
0.53	GO:0070013	intracellular organelle lumen
0.47	GO:0044446	intracellular organelle part
0.42	GO:0005737	cytoplasm
0.37	GO:0043005	neuron projection
0.36	GO:0005694	chromosome
0.35	GO:0005886	plasma membrane
0.33	GO:0005667	transcription factor complex

sp|Q12840|KIF5A_HUMAN
Kinesin heavy chain isoform 5A
Search

KIF5A

0.92	Neuronal kinesin heavy chain

0.74	GO:0007018	microtubule-based movement
0.59	GO:0030705	cytoskeleton-dependent intracellular transport
0.59	GO:0097120	receptor localization to synapse
0.50	GO:0016192	vesicle-mediated transport
0.48	GO:0120036	plasma membrane bounded cell projection organization
0.47	GO:0048667	cell morphogenesis involved in neuron differentiation
0.47	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.45	GO:0006935	chemotaxis
0.42	GO:0008104	protein localization
0.40	GO:0051654	establishment of mitochondrion localization

0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.58	GO:0019894	kinesin binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0042623	ATPase activity, coupled
0.41	GO:0016307	phosphatidylinositol phosphate kinase activity
0.37	GO:0097110	scaffold protein binding
0.35	GO:0032403	protein complex binding

0.60	GO:0035253	ciliary rootlet
0.59	GO:0032839	dendrite cytoplasm
0.55	GO:0043025	neuronal cell body
0.48	GO:0005871	kinesin complex
0.41	GO:0005874	microtubule
0.41	GO:0048471	perinuclear region of cytoplasm
0.40	GO:0030424	axon
0.38	GO:0090724	central region of growth cone
0.37	GO:0097440	apical dendrite
0.36	GO:0005829	cytosol

0.41

GO:0016307

sp|Q12841|FSTL1_HUMAN
Follistatin-related protein 1
Search

FSTL1

0.97	Follistatin like 1

0.52	GO:0042594	response to starvation
0.46	GO:0060034	notochord cell differentiation
0.44	GO:0030510	regulation of BMP signaling pathway
0.41	GO:0009953	dorsal/ventral pattern formation
0.36	GO:1901390	positive regulation of transforming growth factor beta activation
0.35	GO:0030509	BMP signaling pathway
0.35	GO:0010469	regulation of receptor activity
0.35	GO:0043687	post-translational protein modification
0.34	GO:0000387	spliceosomal snRNP assembly

0.67	GO:0005509	calcium ion binding
0.41	GO:0008201	heparin binding
0.36	GO:0005515	protein binding
0.35	GO:0030545	receptor regulator activity

0.50	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.35	GO:0005788	endoplasmic reticulum lumen
0.35	GO:0032797	SMN complex

sp|Q12846|STX4_HUMAN
Syntaxin-4
Search

STX4

0.95	Renal carcinoma antigen NY-REN-31

0.69	GO:0016192	vesicle-mediated transport
0.68	GO:0006886	intracellular protein transport
0.67	GO:0061025	membrane fusion
0.65	GO:0007340	acrosome reaction
0.63	GO:0033194	response to hydroperoxide
0.62	GO:1902568	positive regulation of eosinophil activation
0.62	GO:0043309	regulation of eosinophil degranulation
0.61	GO:0051024	positive regulation of immunoglobulin secretion
0.60	GO:2000010	positive regulation of protein localization to cell surface
0.60	GO:0043302	positive regulation of leukocyte degranulation

0.79	GO:0005484	SNAP receptor activity
0.63	GO:0016230	sphingomyelin phosphodiesterase activator activity
0.59	GO:0000149	SNARE binding
0.40	GO:0046983	protein dimerization activity
0.35	GO:0030507	spectrin binding
0.35	GO:0017137	Rab GTPase binding
0.34	GO:0048306	calcium-dependent protein binding

0.60	GO:0043219	lateral loop
0.60	GO:0035749	myelin sheath adaxonal region
0.59	GO:0031201	SNARE complex
0.59	GO:0030027	lamellipodium
0.59	GO:0016323	basolateral plasma membrane
0.59	GO:0042581	specific granule
0.58	GO:0043197	dendritic spine
0.56	GO:0045335	phagocytic vesicle
0.54	GO:0005615	extracellular space
0.54	GO:0005802	trans-Golgi network

sp|Q12849|GRSF1_HUMAN
G-rich sequence factor 1
Search

sp|Q12851|M4K2_HUMAN
Mitogen-activated protein kinase kinase kinase kinase 2
Search

MAP4K2

0.76	Mitogen-activated protein kinase kinase kinase kinase

0.84	GO:0000185	activation of MAPKKK activity
0.77	GO:0000165	MAPK cascade
0.58	GO:0031098	stress-activated protein kinase signaling cascade
0.57	GO:0006903	vesicle targeting
0.56	GO:0043507	positive regulation of JUN kinase activity
0.56	GO:0000187	activation of MAPK activity
0.47	GO:0007346	regulation of mitotic cell cycle
0.47	GO:0042981	regulation of apoptotic process
0.39	GO:0045087	innate immune response
0.36	GO:0035332	positive regulation of hippo signaling

0.85	GO:0008349	MAP kinase kinase kinase kinase activity
0.58	GO:0031435	mitogen-activated protein kinase kinase kinase binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0008270	zinc ion binding
0.32	GO:0003723	RNA binding

0.44	GO:0005622	intracellular
0.39	GO:0016323	basolateral plasma membrane
0.37	GO:0098588	bounding membrane of organelle
0.37	GO:0012505	endomembrane system
0.33	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.85

GO:0008349

sp|Q12852|M3K12_HUMAN
Mitogen-activated protein kinase kinase kinase 12
Search

MAP3K12

0.76	Mitogen-activated protein kinase kinase kinase

0.83	GO:0000186	activation of MAPKK activity
0.80	GO:0046777	protein autophosphorylation
0.79	GO:0000165	MAPK cascade
0.71	GO:0031098	stress-activated protein kinase signaling cascade
0.49	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.48	GO:2000672	negative regulation of motor neuron apoptotic process
0.46	GO:0016572	histone phosphorylation
0.46	GO:0018107	peptidyl-threonine phosphorylation
0.45	GO:0018105	peptidyl-serine phosphorylation

0.84	GO:0004709	MAP kinase kinase kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0042803	protein homodimerization activity
0.44	GO:0019901	protein kinase binding
0.37	GO:0046872	metal ion binding

0.47	GO:0008385	IkappaB kinase complex
0.46	GO:0030426	growth cone
0.45	GO:0030424	axon
0.38	GO:0005886	plasma membrane

0.84

EC:2.7.11 EC:2.7.11.25

GO:0004709

sp|Q12857|NFIA_HUMAN
Nuclear factor 1 A-type
Search

NFIA

0.77	Nuclear factor 1 A-type

0.66	GO:0006260	DNA replication
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0006351	transcription, DNA-templated
0.54	GO:0060074	synapse maturation
0.54	GO:0072189	ureter development
0.49	GO:0051254	positive regulation of RNA metabolic process
0.49	GO:0010557	positive regulation of macromolecule biosynthetic process
0.49	GO:0031328	positive regulation of cellular biosynthetic process

0.61	GO:0003700	DNA binding transcription factor activity
0.53	GO:0003677	DNA binding
0.49	GO:0003682	chromatin binding
0.48	GO:0001067	regulatory region nucleic acid binding
0.47	GO:0008134	transcription factor binding

0.61	GO:0005634	nucleus
0.48	GO:0030054	cell junction
0.45	GO:0031974	membrane-enclosed lumen
0.41	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|Q12860|CNTN1_HUMAN
Contactin-1
Search

CNTN1

0.92	LOW QUALITY PROTEIN: contactin-1

0.78	GO:0031175	neuron projection development
0.53	GO:0010765	positive regulation of sodium ion transport
0.52	GO:0021549	cerebellum development
0.51	GO:0010976	positive regulation of neuron projection development
0.47	GO:0010628	positive regulation of gene expression
0.41	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
0.39	GO:0007219	Notch signaling pathway
0.38	GO:0007155	cell adhesion

0.46	GO:0030246	carbohydrate binding
0.36	GO:0005515	protein binding

0.51	GO:0043209	myelin sheath
0.40	GO:0045121	membrane raft
0.40	GO:0031225	anchored component of membrane
0.37	GO:0070062	extracellular exosome
0.35	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q12864|CAD17_HUMAN
Cadherin-17
Search

CDH17

0.97	Liver-intestine cadherin

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.66	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.66	GO:0033626	positive regulation of integrin activation by cell surface receptor linked signal transduction
0.65	GO:0002314	germinal center B cell differentiation
0.64	GO:0002315	marginal zone B cell differentiation
0.62	GO:0048536	spleen development
0.61	GO:0035672	oligopeptide transmembrane transport
0.57	GO:0007229	integrin-mediated signaling pathway
0.40	GO:0002456	T cell mediated immunity
0.37	GO:0007399	nervous system development

0.70	GO:0005509	calcium ion binding
0.69	GO:0005427	proton-dependent oligopeptide secondary active transmembrane transporter activity
0.60	GO:0005178	integrin binding
0.37	GO:0045296	cadherin binding
0.34	GO:0045295	gamma-catenin binding
0.34	GO:0032794	GTPase activating protein binding
0.34	GO:0030506	ankyrin binding
0.34	GO:0008013	beta-catenin binding
0.33	GO:0042802	identical protein binding
0.32	GO:0004872	receptor activity

0.62	GO:0016323	basolateral plasma membrane
0.55	GO:0009986	cell surface
0.54	GO:0030054	cell junction
0.47	GO:0005634	nucleus
0.37	GO:0005887	integral component of plasma membrane
0.36	GO:0016327	apicolateral plasma membrane
0.35	GO:0120025	plasma membrane bounded cell projection
0.34	GO:0032421	stereocilium bundle
0.34	GO:0016600	flotillin complex
0.34	GO:0016342	catenin complex

sp|Q12866|MERTK_HUMAN
Tyrosine-protein kinase Mer
Search

MERTK

0.96	Proto-oncogene tyrosine-protein kinase MER

0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.71	GO:0097350	neutrophil clearance
0.70	GO:0060068	vagina development
0.70	GO:0001779	natural killer cell differentiation
0.68	GO:0043491	protein kinase B signaling
0.68	GO:0043277	apoptotic cell clearance
0.68	GO:2000107	negative regulation of leukocyte apoptotic process
0.67	GO:0050766	positive regulation of phagocytosis
0.67	GO:0034446	substrate adhesion-dependent cell spreading
0.66	GO:0030168	platelet activation

0.77	GO:0004713	protein tyrosine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0019199	transmembrane receptor protein kinase activity
0.38	GO:0005509	calcium ion binding
0.35	GO:0005515	protein binding

0.69	GO:0016028	rhabdomere
0.58	GO:0005615	extracellular space
0.44	GO:0001750	photoreceptor outer segment
0.42	GO:0005737	cytoplasm
0.36	GO:0005887	integral component of plasma membrane

0.77

EC:2.7.10

GO:0004713

sp|Q12870|TCF15_HUMAN
Transcription factor 15
Search

TCF15

0.97	basic helix-loop-helix transcription factor scleraxis

0.58	GO:0061053	somite development
0.58	GO:0007498	mesoderm development
0.57	GO:0003016	respiratory system process
0.57	GO:0060231	mesenchymal to epithelial transition
0.57	GO:0045198	establishment of epithelial cell apical/basal polarity
0.57	GO:0048705	skeletal system morphogenesis
0.57	GO:0050884	neuromuscular process controlling posture
0.57	GO:0042755	eating behavior
0.57	GO:0060485	mesenchyme development
0.56	GO:0036342	post-anal tail morphogenesis

0.68	GO:0046983	protein dimerization activity
0.56	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.56	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.53	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.44	GO:0043425	bHLH transcription factor binding
0.43	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.43	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding

0.53	GO:0005667	transcription factor complex
0.47	GO:0005634	nucleus
0.42	GO:0044446	intracellular organelle part

sp|Q12872|SFSWA_HUMAN
Splicing factor, suppressor of white-apricot homolog
Search

SFSWAP

0.96	Splicing factor, suppressor of white-apricot

0.62	GO:0006396	RNA processing
0.51	GO:0022618	ribonucleoprotein complex assembly
0.49	GO:0016071	mRNA metabolic process
0.40	GO:0048025	negative regulation of mRNA splicing, via spliceosome
0.35	GO:0006351	transcription, DNA-templated
0.35	GO:1903506	regulation of nucleic acid-templated transcription
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0006508	proteolysis
0.31	GO:0007166	cell surface receptor signaling pathway
0.31	GO:0007186	G-protein coupled receptor signaling pathway

0.58	GO:0003723	RNA binding
0.35	GO:0005515	protein binding
0.34	GO:0004222	metalloendopeptidase activity
0.33	GO:0008270	zinc ion binding
0.31	GO:0004930	G-protein coupled receptor activity

0.35	GO:0005634	nucleus
0.34	GO:0031012	extracellular matrix
0.30	GO:0016020	membrane

0.34

GO:0004222

sp|Q12873|CHD3_HUMAN
Chromodomain-helicase-DNA-binding protein 3
Search

CHD3

0.87	Chromodomain helicase DNA binding protein 3

0.78	GO:0007098	centrosome cycle
0.76	GO:0007051	spindle organization
0.71	GO:0006325	chromatin organization
0.47	GO:0048731	system development
0.46	GO:0048589	developmental growth
0.44	GO:1904888	cranial skeletal system development
0.42	GO:0043009	chordate embryonic development
0.42	GO:0060322	head development
0.42	GO:0048598	embryonic morphogenesis
0.38	GO:0060850	regulation of transcription involved in cell fate commitment

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0046872	metal ion binding
0.39	GO:0061628	H3K27me3 modified histone binding
0.37	GO:0004386	helicase activity
0.36	GO:0003677	DNA binding
0.34	GO:0003723	RNA binding

0.82	GO:0090545	CHD-type complex
0.80	GO:0090568	nuclear transcriptional repressor complex
0.78	GO:0000118	histone deacetylase complex
0.55	GO:0005813	centrosome
0.53	GO:0005730	nucleolus
0.40	GO:0005737	cytoplasm
0.37	GO:0016607	nuclear speck

sp|Q12874|SF3A3_HUMAN
Splicing factor 3A subunit 3
Search

SF3A3

0.87	Splicing factor 3A subunit 3

0.73	GO:0000398	mRNA splicing, via spliceosome
0.48	GO:0060218	hematopoietic stem cell differentiation
0.34	GO:0022618	ribonucleoprotein complex assembly
0.33	GO:0006629	lipid metabolic process

0.61	GO:0008270	zinc ion binding
0.58	GO:0003723	RNA binding
0.34	GO:0008970	phosphatidylcholine 1-acylhydrolase activity
0.33	GO:0005515	protein binding

0.74	GO:0005681	spliceosomal complex
0.49	GO:0005654	nucleoplasm
0.45	GO:1902494	catalytic complex
0.33	GO:0005576	extracellular region

0.34

EC:3.1.1.32

GO:0008970

sp|Q12879|NMDE1_HUMAN
Glutamate receptor ionotropic, NMDA 2A
Search

GRIN2A

0.97	Glutamate ionotropic receptor NMDA type subunit 2A

0.78	GO:0060079	excitatory postsynaptic potential
0.75	GO:0035235	ionotropic glutamate receptor signaling pathway
0.59	GO:0034220	ion transmembrane transport
0.58	GO:0033058	directional locomotion
0.57	GO:1900273	positive regulation of long-term synaptic potentiation
0.56	GO:0051930	regulation of sensory perception of pain
0.56	GO:0001975	response to amphetamine
0.56	GO:0042428	serotonin metabolic process
0.56	GO:0042417	dopamine metabolic process
0.56	GO:0001964	startle response

0.80	GO:0005234	extracellularly glutamate-gated ion channel activity
0.75	GO:0004970	ionotropic glutamate receptor activity
0.55	GO:0099604	ligand-gated calcium channel activity
0.53	GO:0022843	voltage-gated cation channel activity
0.39	GO:0042165	neurotransmitter binding
0.38	GO:0016597	amino acid binding
0.36	GO:0008270	zinc ion binding
0.36	GO:0005515	protein binding
0.34	GO:0044877	macromolecular complex binding
0.34	GO:0098772	molecular function regulator

0.76	GO:0098794	postsynapse
0.72	GO:0097060	synaptic membrane
0.67	GO:0030054	cell junction
0.59	GO:0017146	NMDA selective glutamate receptor complex
0.54	GO:0032279	asymmetric synapse
0.53	GO:0008021	synaptic vesicle
0.51	GO:0043005	neuron projection
0.50	GO:0009986	cell surface
0.48	GO:0005783	endoplasmic reticulum
0.42	GO:0044422	organelle part

sp|Q12882|DPYD_HUMAN
Dihydropyrimidine dehydrogenase [NADP(+)]
Search

DPYD

0.89	Dihydropyrimidine dehydrogenase [NADP(+)]

0.85	GO:0019483	beta-alanine biosynthetic process
0.61	GO:0006214	thymidine catabolic process
0.59	GO:0006210	thymine catabolic process
0.55	GO:0006212	uracil catabolic process
0.52	GO:0055114	oxidation-reduction process
0.52	GO:0006145	purine nucleobase catabolic process
0.49	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process
0.35	GO:0051384	response to glucocorticoid
0.35	GO:0007584	response to nutrient
0.35	GO:0007623	circadian rhythm

0.85	GO:0017113	dihydropyrimidine dehydrogenase (NADP+) activity
0.65	GO:0051539	4 iron, 4 sulfur cluster binding
0.51	GO:0042803	protein homodimerization activity
0.51	GO:0004152	dihydroorotate dehydrogenase activity
0.37	GO:0050661	NADP binding
0.36	GO:0002058	uracil binding
0.35	GO:0050660	flavin adenine dinucleotide binding
0.35	GO:0046872	metal ion binding
0.35	GO:0004159	dihydrouracil dehydrogenase (NAD+) activity
0.34	GO:0010181	FMN binding

0.48	GO:0005737	cytoplasm
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.85	EC:1.3.1.2	GO:0017113
0.51	KEGG:R01868	GO:0004152

sp|Q12884|SEPR_HUMAN
Prolyl endopeptidase FAP
Search

FAP

0.97	Fibroblast activation protein alpha

0.80	GO:1902362	melanocyte apoptotic process
0.80	GO:0097325	melanocyte proliferation
0.79	GO:0010710	regulation of collagen catabolic process
0.79	GO:0010716	negative regulation of extracellular matrix disassembly
0.79	GO:0060244	negative regulation of cell proliferation involved in contact inhibition
0.77	GO:1900119	positive regulation of execution phase of apoptosis
0.75	GO:0071850	mitotic cell cycle arrest
0.74	GO:0071158	positive regulation of cell cycle arrest
0.73	GO:0043542	endothelial cell migration
0.62	GO:0051603	proteolysis involved in cellular protein catabolic process

0.72	GO:0005178	integrin binding
0.72	GO:0002020	protease binding
0.69	GO:0004252	serine-type endopeptidase activity
0.68	GO:0008239	dipeptidyl-peptidase activity
0.65	GO:0042803	protein homodimerization activity

0.77	GO:0071438	invadopodium membrane
0.73	GO:0045178	basal part of cell
0.71	GO:0030027	lamellipodium
0.69	GO:0045177	apical part of cell
0.65	GO:0009986	cell surface
0.63	GO:0005615	extracellular space
0.42	GO:0005925	focal adhesion
0.30	GO:0016021	integral component of membrane

0.69

GO:0004252

sp|Q12887|COX10_HUMAN
Protoheme IX farnesyltransferase, mitochondrial
Search

COX10

0.77	Protoheme IX farnesyltransferase, mitochondrial

0.78	GO:0048033	heme o metabolic process
0.70	GO:0006783	heme biosynthetic process
0.58	GO:0008535	respiratory chain complex IV assembly
0.57	GO:0000266	mitochondrial fission
0.57	GO:0046160	heme a metabolic process
0.48	GO:0045333	cellular respiration
0.47	GO:1902600	hydrogen ion transmembrane transport
0.46	GO:0022900	electron transport chain
0.36	GO:0018343	protein farnesylation
0.34	GO:0006119	oxidative phosphorylation

0.78	GO:0008495	protoheme IX farnesyltransferase activity
0.48	GO:0015002	heme-copper terminal oxidase activity
0.48	GO:0016675	oxidoreductase activity, acting on a heme group of donors
0.48	GO:0015078	hydrogen ion transmembrane transporter activity
0.47	GO:0009055	electron transfer activity

0.58	GO:0031966	mitochondrial membrane
0.53	GO:0005730	nucleolus
0.52	GO:0070069	cytochrome complex
0.51	GO:0005829	cytosol
0.34	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.78

EC:2.5.1

GO:0008495

sp|Q12888|TP53B_HUMAN
Tumor suppressor p53-binding protein 1
Search

TP53BP1

0.94	Tumor suppressor p53-binding protein 1

0.85	GO:2000042	negative regulation of double-strand break repair via homologous recombination
0.84	GO:0045830	positive regulation of isotype switching
0.77	GO:0006303	double-strand break repair via nonhomologous end joining
0.75	GO:0045944	positive regulation of transcription by RNA polymerase II
0.74	GO:0051260	protein homooligomerization
0.63	GO:0000077	DNA damage checkpoint
0.52	GO:0071481	cellular response to X-ray
0.42	GO:0051091	positive regulation of DNA binding transcription factor activity
0.42	GO:0016925	protein sumoylation
0.38	GO:0006351	transcription, DNA-templated

0.86	GO:0061649	ubiquitin modification-dependent histone binding
0.82	GO:0001102	RNA polymerase II activating transcription factor binding
0.81	GO:0002039	p53 binding
0.80	GO:0140034	methylation-dependent protein binding
0.78	GO:0042162	telomeric DNA binding
0.75	GO:0001104	RNA polymerase II transcription cofactor activity
0.69	GO:0003684	damaged DNA binding

0.79	GO:0035861	site of double-strand break
0.77	GO:0000784	nuclear chromosome, telomeric region
0.74	GO:0016604	nuclear body
0.74	GO:0000776	kinetochore
0.71	GO:1990391	DNA repair complex
0.70	GO:0005657	replication fork
0.47	GO:0005737	cytoplasm
0.45	GO:0000779	condensed chromosome, centromeric region
0.30	GO:0016020	membrane

sp|Q12889|OVGP1_HUMAN
Oviduct-specific glycoprotein
Search

OVGP1

0.44	oviduct-specific glycoprotein precursor

0.64	GO:0006030	chitin metabolic process
0.60	GO:0005975	carbohydrate metabolic process
0.49	GO:1901072	glucosamine-containing compound catabolic process
0.47	GO:0006026	aminoglycan catabolic process
0.46	GO:2000360	negative regulation of binding of sperm to zona pellucida
0.45	GO:0042737	drug catabolic process
0.43	GO:0007338	single fertilization
0.35	GO:0051240	positive regulation of multicellular organismal process
0.34	GO:0090196	regulation of chemokine secretion
0.34	GO:0002532	production of molecular mediator involved in inflammatory response

0.76	GO:0008061	chitin binding
0.58	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.34	GO:0019900	kinase binding
0.33	GO:0046982	protein heterodimerization activity
0.31	GO:0030554	adenyl nucleotide binding
0.31	GO:0032555	purine ribonucleotide binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.57	GO:0005576	extracellular region
0.46	GO:0035805	egg coat
0.42	GO:0030133	transport vesicle
0.32	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.58

EC:3.2.1

GO:0004553

sp|Q12891|HYAL2_HUMAN
Hyaluronidase-2
Search

HYAL2

0.72	Hyaluronidase

0.66	GO:0042117	monocyte activation
0.65	GO:0010764	negative regulation of fibroblast migration
0.64	GO:0030214	hyaluronan catabolic process
0.64	GO:0071493	cellular response to UV-B
0.64	GO:2000484	positive regulation of interleukin-8 secretion
0.63	GO:2000778	positive regulation of interleukin-6 secretion
0.63	GO:0061099	negative regulation of protein tyrosine kinase activity
0.62	GO:0051898	negative regulation of protein kinase B signaling
0.62	GO:0060586	multicellular organismal iron ion homeostasis
0.62	GO:0071347	cellular response to interleukin-1

0.85	GO:0004415	hyalurononglucosaminidase activity
0.67	GO:0030294	receptor signaling protein tyrosine kinase inhibitor activity
0.66	GO:0033906	hyaluronoglucuronidase activity
0.64	GO:0104005	hijacked molecular function
0.61	GO:0050431	transforming growth factor beta binding
0.61	GO:0005540	hyaluronic acid binding
0.60	GO:0001105	RNA polymerase II transcription coactivator activity
0.59	GO:0030971	receptor tyrosine kinase binding
0.36	GO:0008080	N-acetyltransferase activity

0.61	GO:0005902	microvillus
0.61	GO:0031362	anchored component of external side of plasma membrane
0.59	GO:0016324	apical plasma membrane
0.59	GO:0030139	endocytic vesicle
0.58	GO:0098857	membrane microdomain
0.58	GO:0048471	perinuclear region of cytoplasm
0.58	GO:0005764	lysosome
0.55	GO:0090575	RNA polymerase II transcription factor complex
0.52	GO:0005829	cytosol
0.37	GO:0000139	Golgi membrane

0.85

EC:3.2.1.35

GO:0004415

sp|Q12893|TM115_HUMAN
Transmembrane protein 115
Search

TMEM115

0.75	Testicular tissue protein Li 201

0.81	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.51	GO:0043413	macromolecule glycosylation
0.51	GO:0009101	glycoprotein biosynthetic process
0.45	GO:0036211	protein modification process
0.42	GO:0044267	cellular protein metabolic process
0.35	GO:0001302	replicative cell aging
0.35	GO:0008285	negative regulation of cell proliferation
0.35	GO:0006888	ER to Golgi vesicle-mediated transport
0.33	GO:0015031	protein transport

0.51

GO:0042802

identical protein binding

0.55	GO:0017119	Golgi transport complex
0.55	GO:0032580	Golgi cisterna membrane
0.45	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|Q12894|IFRD2_HUMAN
Interferon-related developmental regulator 2
Search

IFRD2

0.88	Interferon-related developmental regulator 2

0.80	GO:0048671	negative regulation of collateral sprouting
0.78	GO:0043403	skeletal muscle tissue regeneration
0.77	GO:0030517	negative regulation of axon extension
0.72	GO:0014706	striated muscle tissue development
0.72	GO:0042692	muscle cell differentiation
0.42	GO:0007518	myoblast fate determination
0.39	GO:0051091	positive regulation of DNA binding transcription factor activity
0.39	GO:0006955	immune response
0.38	GO:0045944	positive regulation of transcription by RNA polymerase II
0.33	GO:0005975	carbohydrate metabolic process

0.41	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding
0.37	GO:0016779	nucleotidyltransferase activity
0.36	GO:0003723	RNA binding
0.35	GO:0004415	hyalurononglucosaminidase activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.58	GO:0005634	nucleus
0.45	GO:0005737	cytoplasm

0.37

GO:0016779

sp|Q12899|TRI26_HUMAN
Tripartite motif-containing protein 26
Search

TRIM26

0.84	Tripartite motif-containing protein 26

0.63	GO:0046597	negative regulation of viral entry into host cell
0.62	GO:1902187	negative regulation of viral release from host cell
0.58	GO:0051091	positive regulation of DNA binding transcription factor activity
0.57	GO:0045087	innate immune response
0.39	GO:0016567	protein ubiquitination
0.38	GO:0006914	autophagy
0.37	GO:0039536	negative regulation of RIG-I signaling pathway
0.37	GO:0030218	erythrocyte differentiation
0.37	GO:0032480	negative regulation of type I interferon production
0.37	GO:0034097	response to cytokine

0.62	GO:0008270	zinc ion binding
0.39	GO:0004842	ubiquitin-protein transferase activity
0.37	GO:0005515	protein binding
0.36	GO:0060090	molecular adaptor activity
0.36	GO:0061659	ubiquitin-like protein ligase activity
0.35	GO:0016874	ligase activity
0.33	GO:0003677	DNA binding
0.32	GO:0004519	endonuclease activity
0.32	GO:0005487	structural constituent of nuclear pore
0.31	GO:0003723	RNA binding

0.45	GO:0005622	intracellular
0.37	GO:0043227	membrane-bounded organelle
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0044422	organelle part
0.34	GO:0098796	membrane protein complex
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:1990234	transferase complex
0.32	GO:0045293	mRNA editing complex
0.32	GO:0043228	non-membrane-bounded organelle
0.32	GO:1990904	ribonucleoprotein complex

0.35	EC:6	GO:0016874
0.39	KEGG:R03876	GO:0004842

sp|Q12901|ZN155_HUMAN
Zinc finger protein 155
Search

0.72	Zinc finger protein 284

0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:0010468	regulation of gene expression
0.37	GO:0097659	nucleic acid-templated transcription
0.36	GO:0010467	gene expression
0.36	GO:0034645	cellular macromolecule biosynthetic process

0.51	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.42	GO:0003700	DNA binding transcription factor activity
0.35	GO:0005515	protein binding

0.44	GO:0005622	intracellular
0.38	GO:0043227	membrane-bounded organelle
0.37	GO:0031974	membrane-enclosed lumen
0.35	GO:0044422	organelle part

sp|Q12904|AIMP1_HUMAN
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1
Search

AIMP1

0.93	Aminoacyl tRNA synthetase complex interacting multifunctional protein 1

0.55	GO:0001937	negative regulation of endothelial cell proliferation
0.53	GO:0050900	leukocyte migration
0.50	GO:0007267	cell-cell signaling
0.46	GO:0006954	inflammatory response
0.44	GO:0010469	regulation of receptor activity
0.42	GO:0006418	tRNA aminoacylation for protein translation
0.40	GO:0070094	positive regulation of glucagon secretion
0.40	GO:0048514	blood vessel morphogenesis
0.37	GO:0051607	defense response to virus
0.37	GO:0006915	apoptotic process

0.69	GO:0000049	tRNA binding
0.50	GO:0042803	protein homodimerization activity
0.49	GO:0051020	GTPase binding
0.46	GO:0005125	cytokine activity
0.40	GO:0016875	ligase activity, forming carbon-oxygen bonds
0.40	GO:0140101	catalytic activity, acting on a tRNA
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.59	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex
0.50	GO:0009986	cell surface
0.49	GO:0017102	methionyl glutamyl tRNA synthetase complex
0.47	GO:0005829	cytosol
0.37	GO:0030133	transport vesicle
0.36	GO:0005615	extracellular space
0.36	GO:0005794	Golgi apparatus
0.36	GO:0005783	endoplasmic reticulum
0.35	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.40

EC:6.1

GO:0016875

sp|Q12905|ILF2_HUMAN
Interleukin enhancer-binding factor 2
Search

ILF2

0.96	Interleukin enhancer binding factor 2

0.71	GO:0006955	immune response
0.48	GO:0045893	positive regulation of transcription, DNA-templated
0.42	GO:0006351	transcription, DNA-templated
0.35	GO:0002446	neutrophil mediated immunity
0.35	GO:0043299	leukocyte degranulation
0.35	GO:0042119	neutrophil activation

0.57	GO:0003723	RNA binding
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0016740	transferase activity
0.40	GO:0003677	DNA binding
0.34	GO:0005515	protein binding

0.48	GO:0005730	nucleolus
0.44	GO:0005576	extracellular region
0.42	GO:0030529	intracellular ribonucleoprotein complex
0.36	GO:1904724	tertiary granule lumen
0.36	GO:0035580	specific granule lumen
0.36	GO:1904813	ficolin-1-rich granule lumen
0.30	GO:0031224	intrinsic component of membrane

0.50

GO:0016740

sp|Q12906|ILF3_HUMAN
Interleukin enhancer-binding factor 3
Search

ILF3

0.94	Interleukin enhancer-binding factor

0.54	GO:0045071	negative regulation of viral genome replication
0.50	GO:0017148	negative regulation of translation
0.49	GO:0045893	positive regulation of transcription, DNA-templated
0.49	GO:0045892	negative regulation of transcription, DNA-templated
0.45	GO:0006468	protein phosphorylation
0.39	GO:0051607	defense response to virus
0.36	GO:0006357	regulation of transcription by RNA polymerase II
0.35	GO:0006351	transcription, DNA-templated
0.35	GO:0006479	protein methylation
0.35	GO:0007275	multicellular organism development

0.76	GO:0003725	double-stranded RNA binding
0.42	GO:0003677	DNA binding
0.36	GO:0001067	regulatory region nucleic acid binding
0.36	GO:0048027	mRNA 5'-UTR binding
0.34	GO:0005515	protein binding
0.33	GO:0003700	DNA binding transcription factor activity

0.50	GO:0005730	nucleolus
0.48	GO:0005654	nucleoplasm
0.46	GO:0005576	extracellular region
0.44	GO:1990904	ribonucleoprotein complex
0.44	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

sp|Q12907|LMAN2_HUMAN
Vesicular integral-membrane protein VIP36
Search

LMAN2

0.94	Vesicular integral-membrane protein VIP36

0.58	GO:0050766	positive regulation of phagocytosis
0.55	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.37	GO:0015031	protein transport
0.34	GO:0005975	carbohydrate metabolic process

0.58	GO:0005537	mannose binding
0.53	GO:0031072	heat shock protein binding
0.34	GO:0046872	metal ion binding
0.34	GO:0016757	transferase activity, transferring glycosyl groups
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.56	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.52	GO:0009986	cell surface
0.51	GO:0005794	Golgi apparatus
0.51	GO:0005615	extracellular space
0.48	GO:0005887	integral component of plasma membrane
0.38	GO:0031984	organelle subcompartment
0.37	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.37	GO:0044432	endoplasmic reticulum part
0.37	GO:0098588	bounding membrane of organelle
0.37	GO:0031982	vesicle

0.34

EC:2.4

GO:0016757

sp|Q12908|NTCP2_HUMAN
Ileal sodium/bile acid cotransporter
Search

SLC10A2

0.96	Solute carrier family 10 (Sodium/bile acid cotransporter family), member 2

0.79	GO:0015721	bile acid and bile salt transport
0.67	GO:0043251	sodium-dependent organic anion transport
0.38	GO:0006814	sodium ion transport
0.35	GO:0055085	transmembrane transport

0.81	GO:0008508	bile acid:sodium symporter activity
0.67	GO:0043250	sodium-dependent organic anion transmembrane transporter activity

0.72	GO:0016324	apical plasma membrane
0.59	GO:0005902	microvillus
0.30	GO:0016021	integral component of membrane

sp|Q12912|LRMP_HUMAN
Lymphoid-restricted membrane protein
Search

LRMP

0.85	Lymphoid-restricted membrane protein (Fragment)

0.42	GO:0007338	single fertilization
0.40	GO:0043312	neutrophil degranulation
0.39	GO:0048284	organelle fusion
0.39	GO:0006903	vesicle targeting
0.38	GO:0016050	vesicle organization
0.37	GO:0061025	membrane fusion
0.35	GO:0007097	nuclear migration
0.35	GO:0051984	positive regulation of chromosome segregation
0.34	GO:0007052	mitotic spindle organization
0.34	GO:0006997	nucleus organization

0.35

GO:0005515

protein binding

0.42	GO:0005789	endoplasmic reticulum membrane
0.41	GO:0000922	spindle pole
0.40	GO:0035577	azurophil granule membrane
0.40	GO:0005635	nuclear envelope
0.40	GO:0005815	microtubule organizing center
0.39	GO:0005694	chromosome
0.36	GO:0005887	integral component of plasma membrane
0.34	GO:0072686	mitotic spindle

sp|Q12913|PTPRJ_HUMAN
Receptor-type tyrosine-protein phosphatase eta
Search

PTPRJ

0.41	Receptor-type tyrosine-protein phosphatase eta

0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.63	GO:0043116	negative regulation of vascular permeability
0.62	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway
0.62	GO:0050860	negative regulation of T cell receptor signaling pathway
0.62	GO:0051894	positive regulation of focal adhesion assembly
0.61	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway
0.61	GO:0048008	platelet-derived growth factor receptor signaling pathway
0.61	GO:0051898	negative regulation of protein kinase B signaling
0.60	GO:0050918	positive chemotaxis
0.60	GO:0051897	positive regulation of protein kinase B signaling

0.74	GO:0004725	protein tyrosine phosphatase activity
0.64	GO:0070097	delta-catenin binding
0.63	GO:0045295	gamma-catenin binding
0.62	GO:0005161	platelet-derived growth factor receptor binding
0.62	GO:0051019	mitogen-activated protein kinase binding
0.59	GO:0008013	beta-catenin binding
0.32	GO:0005509	calcium ion binding
0.31	GO:0003677	DNA binding

0.61	GO:0001772	immunological synapse
0.55	GO:0005911	cell-cell junction
0.54	GO:0009986	cell surface
0.44	GO:0032587	ruffle membrane
0.41	GO:0070062	extracellular exosome
0.39	GO:0035579	specific granule membrane
0.36	GO:0005887	integral component of plasma membrane

0.74

GO:0004725

sp|Q12918|KLRB1_HUMAN
Killer cell lectin-like receptor subfamily B member 1
Search

0.97	Killer cell lectin like receptor B1

0.42	GO:0042269	regulation of natural killer cell mediated cytotoxicity
0.41	GO:0002716	negative regulation of natural killer cell mediated immunity
0.40	GO:0001911	negative regulation of leukocyte mediated cytotoxicity
0.37	GO:0007166	cell surface receptor signaling pathway
0.36	GO:0002717	positive regulation of natural killer cell mediated immunity
0.36	GO:0001912	positive regulation of leukocyte mediated cytotoxicity
0.36	GO:0030101	natural killer cell activation

0.69	GO:0030246	carbohydrate binding
0.39	GO:0042803	protein homodimerization activity
0.39	GO:0004872	receptor activity
0.36	GO:0004871	signal transducer activity

0.40	GO:0009897	external side of plasma membrane
0.37	GO:0005887	integral component of plasma membrane

sp|Q12923|PTN13_HUMAN
Tyrosine-protein phosphatase non-receptor type 13
Search

PTPN13

0.88	tyrosine-protein phosphatase non-receptor type 13

0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.52	GO:0014066	regulation of phosphatidylinositol 3-kinase signaling
0.42	GO:0070830	bicellular tight junction assembly
0.30	GO:0008654	phospholipid biosynthetic process
0.30	GO:0042221	response to chemical
0.30	GO:0046486	glycerolipid metabolic process
0.30	GO:0051716	cellular response to stimulus

0.75	GO:0004725	protein tyrosine phosphatase activity
0.55	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding

0.65	GO:0005856	cytoskeleton
0.51	GO:0030027	lamellipodium
0.43	GO:0005634	nucleus
0.41	GO:0030496	midbody
0.41	GO:0044297	cell body
0.40	GO:0005886	plasma membrane
0.40	GO:0043005	neuron projection
0.38	GO:0070062	extracellular exosome
0.38	GO:0005737	cytoplasm
0.30	GO:0031974	membrane-enclosed lumen

0.75

GO:0004725

sp|Q12926|ELAV2_HUMAN
ELAV-like protein 2
Search

ELAVL2

0.82	ELAV-like protein 2

0.62	GO:1990830	cellular response to leukemia inhibitory factor
0.53	GO:0007275	multicellular organism development
0.52	GO:0008298	intracellular mRNA localization
0.50	GO:0051260	protein homooligomerization
0.50	GO:0000122	negative regulation of transcription by RNA polymerase II
0.49	GO:0000398	mRNA splicing, via spliceosome

0.61	GO:0003730	mRNA 3'-UTR binding
0.59	GO:0017131	uridine-rich cytoplasmic polyadenylylation element binding
0.44	GO:0005515	protein binding

0.56	GO:0005938	cell cortex
0.48	GO:0030529	intracellular ribonucleoprotein complex
0.47	GO:0005654	nucleoplasm

sp|Q12929|EPS8_HUMAN
Epidermal growth factor receptor kinase substrate 8
Search

EPS8

0.95	Epidermal growth factor receptor pathway substrate 8

0.83	GO:0051016	barbed-end actin filament capping
0.83	GO:0051017	actin filament bundle assembly
0.75	GO:0009967	positive regulation of signal transduction
0.67	GO:0070358	actin polymerization-dependent cell motility
0.64	GO:0016601	Rac protein signal transduction
0.64	GO:0036336	dendritic cell migration
0.63	GO:0051764	actin crosslink formation
0.63	GO:0010458	exit from mitosis
0.63	GO:0048149	behavioral response to ethanol
0.61	GO:1990830	cellular response to leukemia inhibitory factor

0.83	GO:0035591	signaling adaptor activity
0.73	GO:0003779	actin binding
0.62	GO:0048365	Rac GTPase binding
0.51	GO:0016301	kinase activity
0.36	GO:0003723	RNA binding
0.35	GO:0030674	protein binding, bridging

0.64	GO:0017146	NMDA selective glutamate receptor complex
0.63	GO:0032426	stereocilium tip
0.62	GO:0032587	ruffle membrane
0.61	GO:0005903	brush border
0.60	GO:0014069	postsynaptic density
0.56	GO:0005938	cell cortex
0.41	GO:0030426	growth cone
0.39	GO:0030054	cell junction
0.37	GO:0070062	extracellular exosome

sp|Q12931|TRAP1_HUMAN
Heat shock protein 75 kDa, mitochondrial
Search

TRAP1

0.82	TNF receptor-associated protein 1

0.71	GO:0009386	translational attenuation
0.69	GO:0006457	protein folding
0.68	GO:1901856	negative regulation of cellular respiration
0.62	GO:0006950	response to stress

0.71	GO:0051082	unfolded protein binding
0.60	GO:0019901	protein kinase binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.58	GO:0005759	mitochondrial matrix
0.55	GO:0005654	nucleoplasm
0.50	GO:0031966	mitochondrial membrane
0.50	GO:0019866	organelle inner membrane

sp|Q12933|TRAF2_HUMAN
TNF receptor-associated factor 2
Search

TRAF2

0.83	TNF receptor-associated factor 2

0.84	GO:0007250	activation of NF-kappaB-inducing kinase activity
0.82	GO:0033209	tumor necrosis factor-mediated signaling pathway
0.82	GO:0051865	protein autoubiquitination
0.79	GO:0046328	regulation of JNK cascade
0.74	GO:0042981	regulation of apoptotic process
0.71	GO:1903721	positive regulation of I-kappaB phosphorylation
0.70	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway
0.69	GO:0071732	cellular response to nitric oxide
0.68	GO:0090073	positive regulation of protein homodimerization activity
0.68	GO:0051023	regulation of immunoglobulin secretion

0.80	GO:0005164	tumor necrosis factor receptor binding
0.70	GO:0004842	ubiquitin-protein transferase activity
0.70	GO:0005174	CD40 receptor binding
0.68	GO:0031996	thioesterase binding
0.68	GO:0046625	sphingolipid binding
0.64	GO:0019903	protein phosphatase binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0031625	ubiquitin protein ligase binding
0.61	GO:0019901	protein kinase binding
0.57	GO:0042802	identical protein binding

0.70	GO:1990597	AIP1-IRE1 complex
0.70	GO:0097057	TRAF2-GSTP1 complex
0.70	GO:1990604	IRE1-TRAF2-ASK1 complex
0.69	GO:0035631	CD40 receptor complex
0.62	GO:0098857	membrane microdomain
0.59	GO:0009898	cytoplasmic side of plasma membrane
0.59	GO:0012506	vesicle membrane
0.59	GO:0000151	ubiquitin ligase complex
0.55	GO:0005829	cytosol
0.42	GO:0005938	cell cortex

0.70

GO:0004842

sp|Q12934|BFSP1_HUMAN
Filensin
Search

BFSP1

0.97	Beaded filament structural protein 1

0.64	GO:0070307	lens fiber cell development
0.59	GO:0048469	cell maturation
0.36	GO:0007010	cytoskeleton organization

0.62	GO:0005212	structural constituent of eye lens
0.37	GO:0005200	structural constituent of cytoskeleton
0.36	GO:0005515	protein binding

0.78	GO:0005882	intermediate filament
0.41	GO:0005938	cell cortex
0.37	GO:0005886	plasma membrane

sp|Q12946|FOXF1_HUMAN
Forkhead box protein F1
Search

FOXF1

0.94	Forkhead box protein F1-B

0.61	GO:0048566	embryonic digestive tract development
0.60	GO:0014822	detection of wounding
0.60	GO:0048371	lateral mesodermal cell differentiation
0.60	GO:0060461	right lung morphogenesis
0.59	GO:0048567	ectodermal digestive tract morphogenesis
0.59	GO:0097070	ductus arteriosus closure
0.59	GO:0043305	negative regulation of mast cell degranulation
0.59	GO:0060426	lung vasculature development
0.58	GO:0060463	lung lobe morphogenesis
0.58	GO:0072189	ureter development

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0001012	RNA polymerase II regulatory region DNA binding
0.52	GO:0003690	double-stranded DNA binding
0.40	GO:0008134	transcription factor binding
0.33	GO:0008536	Ran GTPase binding

0.61	GO:0005634	nucleus
0.42	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

sp|Q12947|FOXF2_HUMAN
Forkhead box protein F2
Search

FOXF2

0.96	Forkhead box protein F2

0.62	GO:0048566	embryonic digestive tract development
0.60	GO:0001738	morphogenesis of a polarized epithelium
0.58	GO:0048562	embryonic organ morphogenesis
0.58	GO:0048806	genitalia development
0.58	GO:0030198	extracellular matrix organization
0.58	GO:0060021	palate development
0.57	GO:0006366	transcription by RNA polymerase II
0.57	GO:0045944	positive regulation of transcription by RNA polymerase II
0.56	GO:0031076	embryonic camera-type eye development
0.55	GO:0007164	establishment of tissue polarity

0.64	GO:0043565	sequence-specific DNA binding
0.60	GO:0003700	DNA binding transcription factor activity
0.58	GO:0001012	RNA polymerase II regulatory region DNA binding
0.55	GO:0003690	double-stranded DNA binding
0.51	GO:0008134	transcription factor binding

0.60	GO:0005634	nucleus
0.53	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

sp|Q12948|FOXC1_HUMAN
Forkhead box protein C1
Search

0.92	Forkhead box protein C1

0.63	GO:1902257	negative regulation of apoptotic process involved in outflow tract morphogenesis
0.61	GO:0048341	paraxial mesoderm formation
0.61	GO:0072010	glomerular epithelium development
0.60	GO:0014032	neural crest cell development
0.60	GO:0060038	cardiac muscle cell proliferation
0.60	GO:0001945	lymph vessel development
0.59	GO:0001974	blood vessel remodeling
0.59	GO:0001756	somitogenesis
0.59	GO:0055010	ventricular cardiac muscle tissue morphogenesis
0.59	GO:0030199	collagen fibril organization

0.62	GO:0043565	sequence-specific DNA binding
0.59	GO:1990841	promoter-specific chromatin binding
0.59	GO:0003700	DNA binding transcription factor activity
0.54	GO:0001223	transcription coactivator binding
0.54	GO:0044212	transcription regulatory region DNA binding
0.52	GO:0008301	DNA binding, bending
0.50	GO:0003713	transcription coactivator activity
0.48	GO:0031490	chromatin DNA binding
0.46	GO:0003690	double-stranded DNA binding
0.44	GO:0042802	identical protein binding

0.59	GO:0005634	nucleus
0.50	GO:0000792	heterochromatin
0.49	GO:0070013	intracellular organelle lumen
0.46	GO:0005829	cytosol

sp|Q12950|FOXD4_HUMAN
Forkhead box protein D4
Search

0.88	Forkhead box protein D4

0.57	GO:0006355	regulation of transcription, DNA-templated
0.52	GO:0030154	cell differentiation
0.52	GO:0009653	anatomical structure morphogenesis
0.44	GO:0006351	transcription, DNA-templated
0.42	GO:1903508	positive regulation of nucleic acid-templated transcription
0.42	GO:0010628	positive regulation of gene expression
0.41	GO:0060485	mesenchyme development
0.40	GO:0072127	renal capsule development
0.39	GO:0007399	nervous system development
0.39	GO:0072268	pattern specification involved in metanephros development

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.41	GO:0008301	DNA binding, bending
0.38	GO:0001012	RNA polymerase II regulatory region DNA binding
0.37	GO:0003690	double-stranded DNA binding
0.35	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.33	GO:0000785	chromatin
0.33	GO:0070013	intracellular organelle lumen

sp|Q12951|FOXI1_HUMAN
Forkhead box protein I1
Search

FOXI1

0.93	Forkhead box protein I1-ema

0.60	GO:0042472	inner ear morphogenesis
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0006366	transcription by RNA polymerase II
0.55	GO:1902680	positive regulation of RNA biosynthetic process
0.49	GO:0030154	cell differentiation
0.44	GO:0008544	epidermis development
0.43	GO:0048890	lateral line ganglion development
0.43	GO:0060429	epithelium development

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.56	GO:0001012	RNA polymerase II regulatory region DNA binding
0.53	GO:0003690	double-stranded DNA binding
0.36	GO:0008301	DNA binding, bending

0.61	GO:0005634	nucleus
0.50	GO:0031974	membrane-enclosed lumen
0.46	GO:0043232	intracellular non-membrane-bounded organelle
0.45	GO:0044446	intracellular organelle part

sp|Q12952|FOXL1_HUMAN
Forkhead box protein L1
Search

FOXL1

0.96	Forkhead box protein L1

0.63	GO:0007495	visceral mesoderm-endoderm interaction involved in midgut development
0.63	GO:0061146	Peyer's patch morphogenesis
0.58	GO:0030166	proteoglycan biosynthetic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0007507	heart development
0.56	GO:0030111	regulation of Wnt signaling pathway
0.47	GO:0030154	cell differentiation
0.42	GO:0035138	pectoral fin morphogenesis

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.37	GO:0008301	DNA binding, bending
0.37	GO:1990841	promoter-specific chromatin binding
0.36	GO:0031490	chromatin DNA binding
0.35	GO:0044212	transcription regulatory region DNA binding
0.35	GO:0042802	identical protein binding
0.33	GO:0042302	structural constituent of cuticle

0.61	GO:0005634	nucleus
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part

sp|Q12955|ANK3_HUMAN
Ankyrin-3
Search

ANK3

0.70	Ankyrin 3, node of Ranvier (ankyrin G)

0.64	GO:0072660	maintenance of protein location in plasma membrane
0.61	GO:0007165	signal transduction
0.58	GO:0043001	Golgi to plasma membrane protein transport
0.56	GO:0007009	plasma membrane organization
0.56	GO:0000281	mitotic cytokinesis
0.53	GO:0071709	membrane assembly
0.51	GO:0007010	cytoskeleton organization
0.35	GO:0055085	transmembrane transport
0.33	GO:1900827	positive regulation of membrane depolarization during cardiac muscle cell action potential
0.33	GO:0010650	positive regulation of cell communication by electrical coupling

0.54	GO:0005200	structural constituent of cytoskeleton
0.47	GO:0030507	spectrin binding
0.33	GO:0044325	ion channel binding
0.32	GO:0045296	cadherin binding
0.32	GO:0030674	protein binding, bridging

0.61	GO:0043194	axon initial segment
0.59	GO:0009925	basal plasma membrane
0.58	GO:0016328	lateral plasma membrane
0.58	GO:0042383	sarcolemma
0.56	GO:0005923	bicellular tight junction
0.48	GO:0043034	costamere
0.33	GO:0014731	spectrin-associated cytoskeleton
0.33	GO:0033268	node of Ranvier
0.33	GO:0014704	intercalated disc
0.33	GO:0016529	sarcoplasmic reticulum

sp|Q12959|DLG1_HUMAN
Disks large homolog 1
Search

DLG1

0.91	Disks large like protein 1

0.82	GO:1903760	regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization
0.81	GO:1903764	regulation of potassium ion export across plasma membrane
0.80	GO:0051660	establishment of centrosome localization
0.80	GO:1903286	regulation of potassium ion import
0.80	GO:1903753	negative regulation of p38MAPK cascade
0.80	GO:0060022	hard palate development
0.79	GO:0001771	immunological synapse formation
0.79	GO:0030432	peristalsis
0.79	GO:0002369	T cell cytokine production
0.78	GO:0030953	astral microtubule organization

0.78	GO:0031434	mitogen-activated protein kinase kinase binding
0.78	GO:0097016	L27 domain binding
0.76	GO:0015459	potassium channel regulator activity
0.74	GO:0044325	ion channel binding
0.73	GO:0008022	protein C-terminus binding
0.72	GO:0019902	phosphatase binding
0.71	GO:0045296	cadherin binding
0.71	GO:0032947	protein complex scaffold activity
0.63	GO:0035255	ionotropic glutamate receptor binding
0.58	GO:0004385	guanylate kinase activity

0.80	GO:0043219	lateral loop
0.79	GO:0035748	myelin sheath abaxonal region
0.78	GO:0033268	node of Ranvier
0.77	GO:0097025	MPP7-DLG1-LIN7 complex
0.77	GO:0005605	basal lamina
0.76	GO:0001772	immunological synapse
0.75	GO:0016328	lateral plasma membrane
0.74	GO:0031594	neuromuscular junction
0.73	GO:0014069	postsynaptic density
0.72	GO:0016323	basolateral plasma membrane

0.58

EC:2.7.4.8

GO:0004385

sp|Q12962|TAF10_HUMAN
Transcription initiation factor TFIID subunit 10
Search

TAF10

0.74	Transcription initiation factor TFIID subunit 10

0.67	GO:0006352	DNA-templated transcription, initiation
0.59	GO:0006413	translational initiation
0.56	GO:0070365	hepatocyte differentiation
0.53	GO:0035264	multicellular organism growth
0.53	GO:0043966	histone H3 acetylation
0.53	GO:0016578	histone deubiquitination
0.52	GO:0051101	regulation of DNA binding
0.52	GO:0000082	G1/S transition of mitotic cell cycle
0.50	GO:0051260	protein homooligomerization
0.50	GO:0006915	apoptotic process

0.60	GO:0003743	translation initiation factor activity
0.54	GO:0030331	estrogen receptor binding
0.51	GO:0004402	histone acetyltransferase activity
0.50	GO:0003713	transcription coactivator activity
0.50	GO:0070063	RNA polymerase binding
0.43	GO:0003700	DNA binding transcription factor activity
0.40	GO:0003677	DNA binding
0.37	GO:0046982	protein heterodimerization activity
0.35	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity

0.59	GO:0005634	nucleus
0.50	GO:0048471	perinuclear region of cytoplasm
0.49	GO:0031248	protein acetyltransferase complex
0.49	GO:0000428	DNA-directed RNA polymerase complex
0.49	GO:0005667	transcription factor complex
0.46	GO:0031974	membrane-enclosed lumen
0.42	GO:0044446	intracellular organelle part

0.51

GO:0004402

sp|Q12965|MYO1E_HUMAN
Unconventional myosin-Ie
Search

MYO1E

0.90	Unconventional myosin-Ie

0.74	GO:0007018	microtubule-based movement
0.61	GO:0003094	glomerular filtration
0.59	GO:0032835	glomerulus development
0.55	GO:0035166	post-embryonic hemopoiesis
0.55	GO:0061318	renal filtration cell differentiation
0.55	GO:0035850	epithelial cell differentiation involved in kidney development
0.55	GO:0048008	platelet-derived growth factor receptor signaling pathway
0.54	GO:0001570	vasculogenesis
0.54	GO:0072009	nephron epithelium development
0.52	GO:0002064	epithelial cell development

0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.74	GO:0003779	actin binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0005516	calmodulin binding
0.50	GO:0035091	phosphatidylinositol binding
0.49	GO:0032403	protein complex binding
0.44	GO:0042623	ATPase activity, coupled

0.77	GO:0016459	myosin complex
0.53	GO:0005903	brush border
0.53	GO:0045334	clathrin-coated endocytic vesicle
0.51	GO:0005912	adherens junction
0.50	GO:0005911	cell-cell junction
0.37	GO:0030864	cortical actin cytoskeleton
0.36	GO:0070062	extracellular exosome
0.36	GO:0031941	filamentous actin
0.35	GO:0031528	microvillus membrane
0.34	GO:0005768	endosome

0.35

GO:0004222

sp|Q12967|GNDS_HUMAN
Ral guanine nucleotide dissociation stimulator
Search

RALGDS

0.95	Ral guanine nucleotide dissociation stimulator

0.77	GO:0007264	small GTPase mediated signal transduction
0.66	GO:0065009	regulation of molecular function

0.75	GO:0005085	guanyl-nucleotide exchange factor activity
0.48	GO:0030695	GTPase regulator activity
0.38	GO:0017160	Ral GTPase binding

0.52	GO:0005903	brush border
0.45	GO:0005829	cytosol
0.43	GO:0005634	nucleus

sp|Q12968|NFAC3_HUMAN
Nuclear factor of activated T-cells, cytoplasmic 3
Search

NFATC3

0.97	Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3

0.59	GO:1902894	negative regulation of pri-miRNA transcription by RNA polymerase II
0.52	GO:0006366	transcription by RNA polymerase II
0.51	GO:0045944	positive regulation of transcription by RNA polymerase II
0.40	GO:0071285	cellular response to lithium ion
0.40	GO:0003299	muscle hypertrophy in response to stress
0.40	GO:0033173	calcineurin-NFAT signaling cascade
0.40	GO:0014887	cardiac muscle adaptation
0.40	GO:0003300	cardiac muscle hypertrophy
0.40	GO:0001974	blood vessel remodeling
0.40	GO:0051145	smooth muscle cell differentiation

0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0003677	DNA binding
0.52	GO:0001067	regulatory region nucleic acid binding
0.38	GO:0003682	chromatin binding
0.37	GO:0008134	transcription factor binding

0.51	GO:0005654	nucleoplasm
0.50	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q12972|PP1R8_HUMAN
Nuclear inhibitor of protein phosphatase 1
Search

PPP1R8

0.94	Nuclear inhibitor of protein phosphatase 1

0.76	GO:0043666	regulation of phosphoprotein phosphatase activity
0.73	GO:0008283	cell proliferation
0.62	GO:0035308	negative regulation of protein dephosphorylation
0.62	GO:0010923	negative regulation of phosphatase activity
0.41	GO:0008380	RNA splicing
0.40	GO:0006397	mRNA processing
0.40	GO:0006886	intracellular protein transport
0.40	GO:0061025	membrane fusion
0.40	GO:0016192	vesicle-mediated transport
0.37	GO:0006351	transcription, DNA-templated

0.77	GO:0019888	protein phosphatase regulator activity
0.62	GO:0019212	phosphatase inhibitor activity
0.58	GO:0003729	mRNA binding
0.43	GO:0005484	SNAP receptor activity
0.38	GO:0008995	ribonuclease E activity
0.37	GO:0003677	DNA binding
0.36	GO:0004519	endonuclease activity
0.35	GO:0008527	taste receptor activity

0.78	GO:0016607	nuclear speck
0.42	GO:0005681	spliceosomal complex
0.33	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q12974|TP4A2_HUMAN
Protein tyrosine phosphatase type IVA 2
Search

PTP4A2

0.92	Tyrosine phosphatase type IVA

0.72	GO:0006470	protein dephosphorylation
0.45	GO:0030335	positive regulation of cell migration
0.37	GO:0007275	multicellular organism development
0.36	GO:0007049	cell cycle
0.34	GO:0043687	post-translational protein modification

0.72	GO:0004721	phosphoprotein phosphatase activity
0.33	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.46	GO:0009898	cytoplasmic side of plasma membrane
0.41	GO:0005634	nucleus
0.41	GO:0005769	early endosome
0.38	GO:0070062	extracellular exosome
0.38	GO:0005819	spindle
0.37	GO:0005783	endoplasmic reticulum
0.33	GO:0005829	cytosol

0.72

GO:0004721

sp|Q12979|ABR_HUMAN
Active breakpoint cluster region-related protein
Search

ABR

0.95	Active breakpoint cluster region-related protein isoform a

0.75	GO:0035023	regulation of Rho protein signal transduction
0.74	GO:0043547	positive regulation of GTPase activity
0.60	GO:0007165	signal transduction
0.58	GO:0043314	negative regulation of neutrophil degranulation
0.57	GO:0060313	negative regulation of blood vessel remodeling
0.56	GO:0002692	negative regulation of cellular extravasation
0.55	GO:0043114	regulation of vascular permeability
0.54	GO:0050766	positive regulation of phagocytosis
0.54	GO:0050885	neuromuscular process controlling balance
0.53	GO:0050728	negative regulation of inflammatory response

0.76	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.75	GO:0005096	GTPase activator activity
0.40	GO:0004674	protein serine/threonine kinase activity

0.46	GO:0005829	cytosol
0.41	GO:0005886	plasma membrane

0.40

GO:0004674

sp|Q12980|NPRL3_HUMAN
Nitrogen permease regulator 3-like protein
Search

NPRL3

0.93	Alpha globin regulatory element containing protein (Predicted)

0.81	GO:0034198	cellular response to amino acid starvation
0.79	GO:0032007	negative regulation of TOR signaling
0.77	GO:0035909	aorta morphogenesis
0.75	GO:0003281	ventricular septum development
0.75	GO:0060021	palate development
0.73	GO:0048738	cardiac muscle tissue development
0.68	GO:0043547	positive regulation of GTPase activity
0.65	GO:0038202	TORC1 signaling
0.63	GO:2000785	regulation of autophagosome assembly
0.36	GO:0006284	base-excision repair

0.68	GO:0005096	GTPase activator activity
0.37	GO:0003905	alkylbase DNA N-glycosylase activity
0.35	GO:0005515	protein binding

0.83	GO:1990130	GATOR1 complex
0.73	GO:0005765	lysosomal membrane
0.30	GO:0016021	integral component of membrane

0.37

EC:3.2.2.21

GO:0003905

sp|Q12981|SEC20_HUMAN
Vesicle transport protein SEC20
Search

BNIP1

0.89	BCL2 interacting protein 1

0.77	GO:0016320	endoplasmic reticulum membrane fusion
0.70	GO:0007029	endoplasmic reticulum organization
0.66	GO:0006915	apoptotic process

0.69

GO:0005484

SNAP receptor activity

0.70	GO:0031201	SNARE complex
0.65	GO:0005635	nuclear envelope
0.61	GO:0005783	endoplasmic reticulum
0.30	GO:0031224	intrinsic component of membrane

sp|Q12982|BNIP2_HUMAN
BCL2/adenovirus E1B 19 kDa protein-interacting protein 2
Search

BNIP2

0.95	BCL2 interacting protein 2

0.83	GO:0051057	positive regulation of small GTPase mediated signal transduction
0.80	GO:0007098	centrosome cycle
0.79	GO:0051146	striated muscle cell differentiation
0.79	GO:0045666	positive regulation of neuron differentiation
0.77	GO:0001824	blastocyst development
0.77	GO:0043410	positive regulation of MAPK cascade
0.61	GO:0006915	apoptotic process

0.58

GO:0042802

identical protein binding

0.85	GO:0031616	spindle pole centrosome
0.80	GO:0005814	centriole
0.55	GO:0005829	cytosol

sp|Q12983|BNIP3_HUMAN
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
Search

BNIP3

0.66	BCL2 interacting protein 3

0.79	GO:0043065	positive regulation of apoptotic process
0.59	GO:0035694	mitochondrial protein catabolic process
0.58	GO:0097345	mitochondrial outer membrane permeabilization
0.56	GO:1990144	intrinsic apoptotic signaling pathway in response to hypoxia
0.56	GO:0016239	positive regulation of macroautophagy
0.56	GO:0045837	negative regulation of membrane potential
0.55	GO:0010821	regulation of mitochondrion organization
0.55	GO:0071279	cellular response to cobalt ion
0.54	GO:0008626	granzyme-mediated apoptotic signaling pathway
0.54	GO:0043653	mitochondrial fragmentation involved in apoptotic process

0.52	GO:0042803	protein homodimerization activity
0.51	GO:0046982	protein heterodimerization activity
0.47	GO:0051020	GTPase binding
0.45	GO:0005521	lamin binding

0.62	GO:0005740	mitochondrial envelope
0.54	GO:0031968	organelle outer membrane
0.53	GO:0005635	nuclear envelope
0.51	GO:0014069	postsynaptic density
0.48	GO:0031301	integral component of organelle membrane
0.46	GO:0005783	endoplasmic reticulum
0.43	GO:0016607	nuclear speck
0.38	GO:0030425	dendrite
0.35	GO:0005829	cytosol

sp|Q12986|NFX1_HUMAN
Transcriptional repressor NF-X1
Search

NFX1

0.95	Nuclear transcription factor, X-box binding 1

0.58	GO:0045347	negative regulation of MHC class II biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.50	GO:1902679	negative regulation of RNA biosynthetic process
0.44	GO:0006366	transcription by RNA polymerase II
0.35	GO:0006954	inflammatory response
0.34	GO:0016032	viral process
0.32	GO:0006414	translational elongation
0.31	GO:0033617	mitochondrial respiratory chain complex IV assembly

0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.53	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.36	GO:0016874	ligase activity
0.35	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.48	GO:0005829	cytosol
0.47	GO:0031974	membrane-enclosed lumen
0.44	GO:0043232	intracellular non-membrane-bounded organelle
0.43	GO:0044446	intracellular organelle part
0.42	GO:0005886	plasma membrane
0.31	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.36

GO:0016874

sp|Q12988|HSPB3_HUMAN
Heat shock protein beta-3
Search

HSPB3

0.97	Heat shock protein beta-3

0.39

GO:0006986

response to unfolded protein

0.46	GO:0005212	structural constituent of eye lens
0.37	GO:0035091	phosphatidylinositol binding

0.60	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm

sp|Q12996|CSTF3_HUMAN
Cleavage stimulation factor subunit 3
Search

CSTF3

0.94	Cleavage stimulation factor subunit 3

0.68	GO:0006397	mRNA processing
0.45	GO:0006379	mRNA cleavage
0.44	GO:0031123	RNA 3'-end processing
0.35	GO:0006369	termination of RNA polymerase II transcription
0.35	GO:0043631	RNA polyadenylation
0.34	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
0.32	GO:0006468	protein phosphorylation

0.44	GO:0003729	mRNA binding
0.35	GO:0005515	protein binding
0.32	GO:0004672	protein kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.60	GO:0005634	nucleus
0.47	GO:0031974	membrane-enclosed lumen
0.42	GO:0044446	intracellular organelle part

sp|Q12999|TSN31_HUMAN
Tetraspanin-31
Search

TSPAN31

0.91	Tetraspanin-31-A

0.49	GO:1903169	regulation of calcium ion transmembrane transport
0.46	GO:0007166	cell surface receptor signaling pathway
0.43	GO:0065009	regulation of molecular function
0.35	GO:0008284	positive regulation of cell proliferation

0.50	GO:0005246	calcium channel regulator activity
0.33	GO:0005515	protein binding

0.44

GO:0005887

integral component of plasma membrane

sp|Q13002|GRIK2_HUMAN
Glutamate receptor ionotropic, kainate 2
Search

GRIK2

0.82	Glutamate ionotropic receptor kainate type subunit 2

0.78	GO:0060079	excitatory postsynaptic potential
0.75	GO:0035235	ionotropic glutamate receptor signaling pathway
0.59	GO:0034220	ion transmembrane transport
0.56	GO:0048172	regulation of short-term neuronal synaptic plasticity
0.55	GO:0051967	negative regulation of synaptic transmission, glutamatergic
0.54	GO:0060080	inhibitory postsynaptic potential
0.54	GO:0050806	positive regulation of synaptic transmission
0.53	GO:0035249	synaptic transmission, glutamatergic
0.53	GO:0048169	regulation of long-term neuronal synaptic plasticity
0.53	GO:0001662	behavioral fear response

0.80	GO:0005234	extracellularly glutamate-gated ion channel activity
0.75	GO:0004970	ionotropic glutamate receptor activity
0.52	GO:0099094	ligand-gated cation channel activity
0.52	GO:0005272	sodium channel activity
0.50	GO:0098782	mechanosensitived potassium channel activity
0.39	GO:0031624	ubiquitin conjugating enzyme binding
0.38	GO:0030165	PDZ domain binding
0.38	GO:0042803	protein homodimerization activity
0.37	GO:0031625	ubiquitin protein ligase binding
0.35	GO:0016595	glutamate binding

0.77	GO:0045211	postsynaptic membrane
0.72	GO:0030054	cell junction
0.55	GO:0032983	kainate selective glutamate receptor complex
0.53	GO:0042734	presynaptic membrane
0.51	GO:0014069	postsynaptic density
0.50	GO:0043025	neuronal cell body
0.40	GO:0030425	dendrite
0.39	GO:0030424	axon
0.39	GO:0043679	axon terminus
0.38	GO:0120111	neuron projection cytoplasm

sp|Q13003|GRIK3_HUMAN
Glutamate receptor ionotropic, kainate 3
Search

GRIK3

0.93	Glutamate ionotropic receptor kainate type subunit 3

0.79	GO:0060079	excitatory postsynaptic potential
0.76	GO:0035235	ionotropic glutamate receptor signaling pathway
0.60	GO:0034220	ion transmembrane transport
0.56	GO:0007196	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway
0.51	GO:0051967	negative regulation of synaptic transmission, glutamatergic
0.50	GO:0048172	regulation of short-term neuronal synaptic plasticity
0.49	GO:0060080	inhibitory postsynaptic potential
0.48	GO:0048169	regulation of long-term neuronal synaptic plasticity
0.48	GO:0001662	behavioral fear response
0.48	GO:0035249	synaptic transmission, glutamatergic

0.82	GO:0005234	extracellularly glutamate-gated ion channel activity
0.77	GO:0004970	ionotropic glutamate receptor activity
0.57	GO:0099094	ligand-gated cation channel activity
0.57	GO:0005272	sodium channel activity
0.57	GO:0001640	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity
0.55	GO:0098782	mechanosensitived potassium channel activity
0.38	GO:0031624	ubiquitin conjugating enzyme binding
0.37	GO:0030165	PDZ domain binding
0.37	GO:0031625	ubiquitin protein ligase binding
0.36	GO:0042803	protein homodimerization activity

0.79	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.50	GO:0032983	kainate selective glutamate receptor complex
0.48	GO:0042734	presynaptic membrane
0.47	GO:0043025	neuronal cell body
0.47	GO:0014069	postsynaptic density
0.40	GO:0032839	dendrite cytoplasm
0.40	GO:0043195	terminal bouton
0.35	GO:0043197	dendritic spine

sp|Q13007|IL24_HUMAN
Interleukin-24
Search

IL24

0.97	Interleukin-24

0.64	GO:0042501	serine phosphorylation of STAT protein
0.61	GO:0071353	cellular response to interleukin-4
0.61	GO:0008285	negative regulation of cell proliferation
0.60	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein
0.60	GO:0006915	apoptotic process
0.59	GO:0071222	cellular response to lipopolysaccharide
0.58	GO:0010469	regulation of receptor activity
0.58	GO:0030336	negative regulation of cell migration
0.57	GO:0042060	wound healing
0.56	GO:0008284	positive regulation of cell proliferation

0.61

GO:0005125

cytokine activity

0.65	GO:0005576	extracellular region
0.49	GO:0005783	endoplasmic reticulum
0.30	GO:0016020	membrane

sp|Q13009|TIAM1_HUMAN
T-lymphoma invasion and metastasis-inducing protein 1
Search

TIAM1

0.97	T-cell lymphoma invasion and metastasis

0.84	GO:0090630	activation of GTPase activity
0.75	GO:0035023	regulation of Rho protein signal transduction
0.61	GO:0016601	Rac protein signal transduction
0.59	GO:0010717	regulation of epithelial to mesenchymal transition
0.59	GO:0032092	positive regulation of protein binding
0.57	GO:0007160	cell-matrix adhesion
0.57	GO:0030335	positive regulation of cell migration
0.56	GO:0008284	positive regulation of cell proliferation
0.55	GO:0016477	cell migration
0.42	GO:0099159	regulation of modification of postsynaptic structure

0.76	GO:0005057	signal transducer activity, downstream of receptor
0.76	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.60	GO:0048365	Rac GTPase binding
0.55	GO:0019900	kinase binding
0.38	GO:0005102	receptor binding
0.38	GO:0008017	microtubule binding
0.37	GO:0008289	lipid binding
0.33	GO:0043168	anion binding

0.59	GO:0044291	cell-cell contact zone
0.56	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.50	GO:0005829	cytosol
0.40	GO:0044295	axonal growth cone
0.40	GO:0032587	ruffle membrane
0.40	GO:0044304	main axon
0.40	GO:0043197	dendritic spine
0.39	GO:0014069	postsynaptic density
0.39	GO:0043025	neuronal cell body
0.39	GO:0097732	9+2 non-motile cilium

sp|Q13011|ECH1_HUMAN
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial
Search

ECH1

0.86	Peroxisomal enoyl coenzyme A hydratase 1

0.39	GO:0006635	fatty acid beta-oxidation
0.36	GO:0006397	mRNA processing

0.53	GO:0016853	isomerase activity
0.46	GO:0005102	receptor binding
0.35	GO:0003723	RNA binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.42	GO:0005739	mitochondrion
0.38	GO:0005777	peroxisome
0.37	GO:0070062	extracellular exosome
0.36	GO:0019013	viral nucleocapsid
0.34	GO:0005634	nucleus
0.34	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016020	membrane

0.53

GO:0016853

sp|Q13015|AF1Q_HUMAN
Protein AF1q
Search

MLLT11

0.40	Myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11

0.82	GO:0097190	apoptotic signaling pathway
0.79	GO:0051901	positive regulation of mitochondrial depolarization
0.77	GO:0090200	positive regulation of release of cytochrome c from mitochondria
0.64	GO:0045893	positive regulation of transcription, DNA-templated
0.63	GO:0007166	cell surface receptor signaling pathway
0.56	GO:0035556	intracellular signal transduction

0.62	GO:0005654	nucleoplasm
0.61	GO:0005829	cytosol

sp|Q13017|RHG05_HUMAN
Rho GTPase-activating protein 5
Search

ARHGAP5

0.92	Rho GTPase-activating protein 5

0.60	GO:0007165	signal transduction
0.41	GO:0030879	mammary gland development
0.39	GO:0043087	regulation of GTPase activity
0.39	GO:0051345	positive regulation of hydrolase activity
0.39	GO:0002053	positive regulation of mesenchymal cell proliferation
0.39	GO:0032535	regulation of cellular component size
0.37	GO:0030335	positive regulation of cell migration
0.37	GO:0000122	negative regulation of transcription by RNA polymerase II
0.37	GO:0043116	negative regulation of vascular permeability
0.36	GO:0051056	regulation of small GTPase mediated signal transduction

0.65	GO:0003924	GTPase activity
0.63	GO:0032550	purine ribonucleoside binding
0.63	GO:0019001	guanyl nucleotide binding
0.56	GO:0042169	SH2 domain binding
0.52	GO:0032555	purine ribonucleotide binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0005096	GTPase activator activity
0.38	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.37	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.37	GO:0005543	phospholipid binding

0.48	GO:0005783	endoplasmic reticulum
0.47	GO:0005829	cytosol
0.36	GO:0036064	ciliary basal body
0.35	GO:0015629	actin cytoskeleton
0.30	GO:0016020	membrane

sp|Q13018|PLA2R_HUMAN
Secretory phospholipase A2 receptor
Search

PLA2R1

0.82	secretory phospholipase A2 receptor

0.51	GO:0030574	collagen catabolic process
0.45	GO:0090238	positive regulation of arachidonic acid secretion
0.45	GO:0090403	oxidative stress-induced premature senescence
0.45	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator
0.44	GO:0090399	replicative senescence
0.43	GO:0001816	cytokine production
0.41	GO:0007165	signal transduction
0.41	GO:0006897	endocytosis
0.41	GO:0072593	reactive oxygen species metabolic process
0.35	GO:0001649	osteoblast differentiation

0.56	GO:0030246	carbohydrate binding
0.49	GO:0005518	collagen binding
0.45	GO:0043274	phospholipase binding
0.44	GO:0004888	transmembrane signaling receptor activity

0.43	GO:0005887	integral component of plasma membrane
0.42	GO:0043235	receptor complex
0.41	GO:0009986	cell surface
0.35	GO:0005925	focal adhesion
0.30	GO:0031982	vesicle
0.30	GO:0005576	extracellular region

sp|Q13021|MALL_HUMAN
MAL-like protein
Search

MALL

0.95	Mal, T-cell differentiation protein like

0.56	GO:0001766	membrane raft polarization
0.52	GO:0042552	myelination
0.44	GO:0008104	protein localization
0.37	GO:0042632	cholesterol homeostasis
0.34	GO:0045056	transcytosis

0.55	GO:0019911	structural constituent of myelin sheath
0.34	GO:0005515	protein binding

0.59	GO:0045121	membrane raft
0.56	GO:0030136	clathrin-coated vesicle
0.53	GO:0000139	Golgi membrane
0.43	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q13023|AKAP6_HUMAN
A-kinase anchor protein 6
Search

AKAP6

0.97	A-kinase anchoring protein alpha

0.86	GO:1902261	positive regulation of delayed rectifier potassium channel activity
0.85	GO:0060306	regulation of membrane repolarization
0.85	GO:0071320	cellular response to cAMP
0.50	GO:0035556	intracellular signal transduction
0.37	GO:0016310	phosphorylation

0.85	GO:0008179	adenylate cyclase binding
0.84	GO:0044325	ion channel binding
0.66	GO:0051018	protein kinase A binding
0.38	GO:0016301	kinase activity

0.85	GO:0016529	sarcoplasmic reticulum
0.79	GO:0048471	perinuclear region of cytoplasm
0.78	GO:0034704	calcium channel complex
0.75	GO:0031965	nuclear membrane

sp|Q13029|PRDM2_HUMAN
PR domain zinc finger protein 2
Search

PRDM2

0.94	PR domain zinc finger protein 2

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.48	GO:0008340	determination of adult lifespan
0.45	GO:0006366	transcription by RNA polymerase II
0.45	GO:1902680	positive regulation of RNA biosynthetic process
0.42	GO:0034968	histone lysine methylation
0.38	GO:0032355	response to estradiol

0.53	GO:0003677	DNA binding
0.52	GO:0046872	metal ion binding
0.47	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.46	GO:0001067	regulatory region nucleic acid binding
0.42	GO:0018024	histone-lysine N-methyltransferase activity
0.35	GO:0005515	protein binding

0.59	GO:0005634	nucleus
0.43	GO:0005794	Golgi apparatus
0.30	GO:0016020	membrane

0.42

GO:0018024

sp|Q13033|STRN3_HUMAN
Striatin-3
Search

STRN3

0.85	Striatin, calmodulin binding protein 3

0.50	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway
0.49	GO:0032355	response to estradiol
0.49	GO:0000122	negative regulation of transcription by RNA polymerase II
0.48	GO:0045944	positive regulation of transcription by RNA polymerase II
0.38	GO:0008285	negative regulation of cell proliferation
0.37	GO:0016055	Wnt signaling pathway

0.86	GO:0070016	armadillo repeat domain binding
0.85	GO:0051721	protein phosphatase 2A binding
0.76	GO:0017048	Rho GTPase binding
0.75	GO:0032403	protein complex binding
0.49	GO:0005516	calmodulin binding
0.42	GO:0003700	DNA binding transcription factor activity
0.39	GO:0030331	estrogen receptor binding
0.37	GO:0019901	protein kinase binding

0.81	GO:0000159	protein phosphatase type 2A complex
0.71	GO:0005794	Golgi apparatus
0.69	GO:0005654	nucleoplasm
0.55	GO:0005886	plasma membrane
0.47	GO:0043025	neuronal cell body
0.47	GO:0030425	dendrite
0.40	GO:0043234	protein complex
0.38	GO:0005923	bicellular tight junction

sp|Q13042|CDC16_HUMAN
Cell division cycle protein 16 homolog
Search

CDC16

0.96	Cell division cycle protein 16

0.60	GO:0070979	protein K11-linked ubiquitination
0.59	GO:0051301	cell division
0.44	GO:0000278	mitotic cell cycle
0.36	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.36	GO:1904667	negative regulation of ubiquitin protein ligase activity
0.35	GO:0031145	anaphase-promoting complex-dependent catabolic process
0.35	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.35	GO:0008283	cell proliferation
0.35	GO:0007088	regulation of mitotic nuclear division
0.34	GO:0022402	cell cycle process

0.35

GO:0005515

protein binding

0.57	GO:0005876	spindle microtubule
0.56	GO:0005680	anaphase-promoting complex
0.55	GO:0005813	centrosome
0.40	GO:0005737	cytoplasm
0.34	GO:0005654	nucleoplasm

sp|Q13043|STK4_HUMAN
Serine/threonine-protein kinase 4
Search

STK4

0.78	Serine/threonine-protein kinase 4

0.63	GO:0060800	regulation of cell differentiation involved in embryonic placenta development
0.62	GO:0097284	hepatocyte apoptotic process
0.62	GO:0006468	protein phosphorylation
0.61	GO:0035329	hippo signaling
0.61	GO:0003157	endocardium development
0.61	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.61	GO:0060215	primitive hemopoiesis
0.60	GO:0046621	negative regulation of organ growth
0.60	GO:0045600	positive regulation of fat cell differentiation
0.59	GO:0032092	positive regulation of protein binding

0.66	GO:0004674	protein serine/threonine kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0042802	identical protein binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0008134	transcription factor binding
0.48	GO:0000287	magnesium ion binding
0.48	GO:0046983	protein dimerization activity
0.35	GO:0043539	protein serine/threonine kinase activator activity

0.52	GO:0016604	nuclear body
0.48	GO:0005829	cytosol
0.45	GO:0043234	protein complex

0.66

GO:0004674

sp|Q13045|FLII_HUMAN
Protein flightless-1 homolog
Search

FLII

0.93	Leucine-rich repeat flightless-interacting protein 1

0.84	GO:0051014	actin filament severing
0.74	GO:0030036	actin cytoskeleton organization
0.50	GO:0048856	anatomical structure development
0.47	GO:0032501	multicellular organismal process
0.43	GO:0097435	supramolecular fiber organization
0.42	GO:0030154	cell differentiation
0.42	GO:0070925	organelle assembly
0.34	GO:0006351	transcription, DNA-templated
0.34	GO:2001141	regulation of RNA biosynthetic process
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.78	GO:0051015	actin filament binding
0.33	GO:0004721	phosphoprotein phosphatase activity

0.54	GO:0005903	brush border
0.51	GO:0005815	microtubule organizing center
0.48	GO:0005654	nucleoplasm
0.47	GO:0005829	cytosol
0.37	GO:0005925	focal adhesion

0.33

GO:0004721

sp|Q13046|PSG7_HUMAN
Putative pregnancy-specific beta-1-glycoprotein 7
Search

PSG3

0.89	Pregnancy-specific beta-1-glycoprotein 8

0.78	GO:0007565	female pregnancy
0.38	GO:0043312	neutrophil degranulation
0.38	GO:0030335	positive regulation of cell migration
0.38	GO:0008284	positive regulation of cell proliferation
0.37	GO:0050900	leukocyte migration
0.37	GO:0006952	defense response

0.37

GO:0005515

protein binding

0.44	GO:0005576	extracellular region
0.39	GO:0035579	specific granule membrane
0.34	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q13049|TRI32_HUMAN
E3 ubiquitin-protein ligase TRIM32
Search

TRIM32

0.96	E3 ubiquitin-protein ligase TRIM32

0.52	GO:1903884	regulation of chemokine (C-C motif) ligand 20 production
0.52	GO:1903883	positive regulation of interleukin-17-mediated signaling pathway
0.52	GO:0007014	actin ubiquitination
0.52	GO:1902187	negative regulation of viral release from host cell
0.51	GO:0032897	negative regulation of viral transcription
0.51	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
0.51	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway
0.50	GO:0048147	negative regulation of fibroblast proliferation
0.50	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.49	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling

0.63	GO:0008270	zinc ion binding
0.61	GO:0016874	ligase activity
0.50	GO:0043621	protein self-association
0.49	GO:0043130	ubiquitin binding
0.48	GO:0017022	myosin binding
0.48	GO:0031369	translation initiation factor binding
0.47	GO:0061630	ubiquitin protein ligase activity
0.46	GO:0042802	identical protein binding
0.40	GO:0003723	RNA binding
0.39	GO:0030957	Tat protein binding

0.51	GO:0005863	striated muscle myosin thick filament
0.41	GO:0005634	nucleus
0.36	GO:0005829	cytosol

0.61

GO:0016874

sp|Q13057|COASY_HUMAN
Bifunctional coenzyme A synthase
Search

COASY

0.93	Bifunctional coenzyme A synthase

0.72	GO:0015937	coenzyme A biosynthetic process
0.56	GO:0016310	phosphorylation
0.32	GO:0055114	oxidation-reduction process

0.77	GO:0004140	dephospho-CoA kinase activity
0.60	GO:0004595	pantetheine-phosphate adenylyltransferase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0046983	protein dimerization activity
0.32	GO:0016491	oxidoreductase activity

0.57	GO:0005759	mitochondrial matrix
0.54	GO:0005654	nucleoplasm
0.53	GO:0005829	cytosol
0.39	GO:0070062	extracellular exosome
0.36	GO:0005741	mitochondrial outer membrane
0.30	GO:0016021	integral component of membrane

0.77	EC:2.7.1.24	GO:0004140
0.77	KEGG:R00130	GO:0004140

sp|Q13061|TRDN_HUMAN
Triadin
Search

TRDN

0.92

Triadin

0.55	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity
0.55	GO:0060047	heart contraction
0.55	GO:0086036	regulation of cardiac muscle cell membrane potential
0.55	GO:0010649	regulation of cell communication by electrical coupling
0.54	GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
0.52	GO:0014808	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
0.51	GO:0006936	muscle contraction
0.44	GO:1903781	positive regulation of cardiac conduction
0.41	GO:0051280	negative regulation of release of sequestered calcium ion into cytosol
0.41	GO:0090158	endoplasmic reticulum membrane organization

0.71	GO:0005102	receptor binding
0.52	GO:0044325	ion channel binding
0.41	GO:0030674	protein binding, bridging
0.32	GO:0005523	tropomyosin binding
0.32	GO:0003785	actin monomer binding
0.32	GO:0030246	carbohydrate binding
0.32	GO:0008270	zinc ion binding
0.31	GO:0003723	RNA binding
0.31	GO:0016887	ATPase activity
0.31	GO:0030554	adenyl nucleotide binding

0.83	GO:0016529	sarcoplasmic reticulum
0.48	GO:0005789	endoplasmic reticulum membrane
0.47	GO:0098588	bounding membrane of organelle
0.45	GO:0005829	cytosol
0.42	GO:0005886	plasma membrane
0.41	GO:0034704	calcium channel complex
0.40	GO:0030314	junctional membrane complex
0.39	GO:0005788	endoplasmic reticulum lumen
0.32	GO:0005802	trans-Golgi network
0.32	GO:0005654	nucleoplasm

0.31

GO:0016887

sp|Q13064|MKRN3_HUMAN
Probable E3 ubiquitin-protein ligase makorin-3
Search

MKRN1

0.94	Makorin ring finger protein 3

0.52	GO:0000209	protein polyubiquitination
0.39	GO:1990823	response to leukemia inhibitory factor
0.38	GO:0071345	cellular response to cytokine stimulus

0.54	GO:0046872	metal ion binding
0.54	GO:0042802	identical protein binding
0.48	GO:0004842	ubiquitin-protein transferase activity
0.38	GO:0003682	chromatin binding
0.35	GO:0003723	RNA binding
0.33	GO:0016874	ligase activity

0.30

GO:0031224

intrinsic component of membrane

0.33	EC:6	GO:0016874
0.48	KEGG:R03876	GO:0004842

sp|Q13065|GAGE1_HUMAN
G antigen 1
Search

0.97	G antigen 1

0.64

GO:0006968

cellular defense response

0.58

GO:0005515

protein binding

sp|Q13066|GAG2B_HUMAN
G antigen 2B/2C
Search

sp|Q13067|GAGE3_HUMAN
G antigen 3
Search

0.41	PAGE family member 1

sp|Q13068|GAGE4_HUMAN
G antigen 4
Search

0.97	X antigen family member 2

0.62	GO:0006968	cellular defense response
0.37	GO:0007155	cell adhesion

0.58	GO:0005515	protein binding
0.37	GO:0044877	macromolecular complex binding

0.37	GO:0005618	cell wall
0.36	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

sp|Q13069|GAGE5_HUMAN
G antigen 5
Search

0.97	G antigen 5

0.63

GO:0006968

cellular defense response

0.58

GO:0005515

protein binding

sp|Q13070|GAGE6_HUMAN
G antigen 6
Search

0.97	G antigen 6

0.63

GO:0006968

cellular defense response

0.58

GO:0005515

protein binding

sp|Q13072|BAGE1_HUMAN
B melanoma antigen 1
Search

0.94	B melanoma antigen 1

0.66

GO:0005576

extracellular region

sp|Q13075|BIRC1_HUMAN
Baculoviral IAP repeat-containing protein 1
Search

NAIP

0.79	Baculoviral IAP repeat-containing protein 1

0.85	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.78	GO:0006915	apoptotic process
0.30	GO:0140014	mitotic nuclear division
0.30	GO:0044238	primary metabolic process
0.30	GO:0042221	response to chemical
0.30	GO:0000226	microtubule cytoskeleton organization
0.30	GO:0030111	regulation of Wnt signaling pathway
0.30	GO:0048731	system development
0.30	GO:0009967	positive regulation of signal transduction
0.30	GO:0044237	cellular metabolic process

0.86	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.51	GO:0032559	adenyl ribonucleotide binding
0.50	GO:0008144	drug binding
0.50	GO:0035639	purine ribonucleoside triphosphate binding
0.30	GO:0016740	transferase activity
0.30	GO:0140096	catalytic activity, acting on a protein
0.30	GO:0043169	cation binding
0.30	GO:0005515	protein binding

0.30	GO:0044459	plasma membrane part
0.30	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane
0.30	GO:0043204	perikaryon
0.30	GO:1903561	extracellular vesicle
0.30	GO:0042995	cell projection
0.30	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0005737	cytoplasm

0.30

GO:0016740

sp|Q13077|TRAF1_HUMAN
TNF receptor-associated factor 1
Search

TRAF1

0.85	Epstein-Barr virus-induced protein 6

0.74	GO:0042981	regulation of apoptotic process
0.63	GO:0051090	regulation of DNA binding transcription factor activity
0.61	GO:0033209	tumor necrosis factor-mediated signaling pathway
0.58	GO:0048583	regulation of response to stimulus
0.56	GO:0044093	positive regulation of molecular function
0.55	GO:0048518	positive regulation of biological process
0.54	GO:0008063	Toll signaling pathway
0.54	GO:0023051	regulation of signaling
0.54	GO:0010646	regulation of cell communication
0.52	GO:0002697	regulation of immune effector process

0.81	GO:0005164	tumor necrosis factor receptor binding
0.63	GO:0031996	thioesterase binding
0.62	GO:0008270	zinc ion binding
0.57	GO:0031625	ubiquitin protein ligase binding
0.52	GO:0042802	identical protein binding
0.46	GO:0004842	ubiquitin-protein transferase activity
0.43	GO:0019903	protein phosphatase binding
0.42	GO:0019901	protein kinase binding
0.34	GO:0005174	CD40 receptor binding
0.34	GO:0046625	sphingolipid binding

0.45	GO:0035631	CD40 receptor complex
0.41	GO:0009898	cytoplasmic side of plasma membrane
0.36	GO:0005622	intracellular
0.34	GO:0031982	vesicle
0.34	GO:0097057	TRAF2-GSTP1 complex
0.34	GO:1990597	AIP1-IRE1 complex
0.34	GO:0012505	endomembrane system
0.33	GO:0098857	membrane microdomain
0.33	GO:0005615	extracellular space
0.33	GO:1990234	transferase complex

0.46

GO:0004842

sp|Q13084|RM28_HUMAN
39S ribosomal protein L28, mitochondrial
Search

MRPL28

0.96	Mitochondrial ribosomal protein L28

0.37	GO:0006487	protein N-linked glycosylation
0.36	GO:0070126	mitochondrial translational termination
0.36	GO:0070125	mitochondrial translational elongation
0.33	GO:0016567	protein ubiquitination

0.64	GO:0003735	structural constituent of ribosome
0.34	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.57	GO:0005762	mitochondrial large ribosomal subunit
0.48	GO:0005829	cytosol
0.37	GO:0008250	oligosaccharyltransferase complex
0.34	GO:0031966	mitochondrial membrane
0.34	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q13085|ACACA_HUMAN
Acetyl-CoA carboxylase 1
Search

ACACA

0.54	Acetyl-Coenzyme A carboxylase alpha

0.69	GO:0006633	fatty acid biosynthetic process
0.57	GO:0044268	multicellular organismal protein metabolic process
0.55	GO:0071380	cellular response to prostaglandin E stimulus
0.54	GO:0051289	protein homotetramerization
0.52	GO:0001894	tissue homeostasis
0.52	GO:0055088	lipid homeostasis
0.50	GO:0006084	acetyl-CoA metabolic process
0.41	GO:2001295	malonyl-CoA biosynthetic process
0.37	GO:0006853	carnitine shuttle
0.36	GO:0045540	regulation of cholesterol biosynthetic process

0.74	GO:0003989	acetyl-CoA carboxylase activity
0.74	GO:0004075	biotin carboxylase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0046872	metal ion binding
0.49	GO:0042802	identical protein binding
0.35	GO:0033293	monocarboxylic acid binding
0.35	GO:0033218	amide binding
0.35	GO:1901681	sulfur compound binding

0.53	GO:0001650	fibrillar center
0.49	GO:0015629	actin cytoskeleton
0.48	GO:0005829	cytosol
0.43	GO:0005739	mitochondrion
0.37	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.74

EC:6.4.1.2

GO:0003989

sp|Q13087|PDIA2_HUMAN
Protein disulfide-isomerase A2
Search

PDIA2

0.93	Protein disulfide isomerase-associated 2 (Predicted)

0.69	GO:0045454	cell redox homeostasis
0.47	GO:1902175	regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
0.47	GO:0055114	oxidation-reduction process
0.46	GO:0019511	peptidyl-proline hydroxylation
0.45	GO:0034976	response to endoplasmic reticulum stress
0.42	GO:0006457	protein folding

0.69	GO:0015037	peptide disulfide oxidoreductase activity
0.63	GO:0016853	isomerase activity
0.46	GO:0031545	peptidyl-proline 4-dioxygenase activity

0.69

GO:0005783

endoplasmic reticulum

0.63

GO:0016853

sp|Q13093|PAFA_HUMAN
Platelet-activating factor acetylhydrolase
Search

PLA2G7

0.91	Platelet-activating factor acetylhydrolase

0.71	GO:0016042	lipid catabolic process
0.63	GO:0034441	plasma lipoprotein particle oxidation
0.62	GO:0046469	platelet activating factor metabolic process
0.60	GO:0034374	low-density lipoprotein particle remodeling
0.59	GO:0090026	positive regulation of monocyte chemotaxis
0.54	GO:0034440	lipid oxidation
0.36	GO:0050729	positive regulation of inflammatory response
0.35	GO:0006954	inflammatory response
0.33	GO:0007596	blood coagulation
0.33	GO:0043066	negative regulation of apoptotic process

0.80	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity
0.61	GO:0047499	calcium-independent phospholipase A2 activity
0.53	GO:0005543	phospholipid binding

0.60	GO:0034362	low-density lipoprotein particle
0.33	GO:0005737	cytoplasm
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0031984	organelle subcompartment
0.32	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0044425	membrane part

0.80

EC:3.1.1.47

GO:0003847

sp|Q13094|LCP2_HUMAN
Lymphocyte cytosolic protein 2
Search

LCP2

0.97	Lymphocyte cytosolic protein 2

0.85	GO:0045576	mast cell activation
0.85	GO:0050852	T cell receptor signaling pathway
0.85	GO:0050663	cytokine secretion
0.77	GO:0045860	positive regulation of protein kinase activity
0.62	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.59	GO:0006955	immune response
0.52	GO:0035556	intracellular signal transduction
0.42	GO:0038095	Fc-epsilon receptor signaling pathway
0.41	GO:0030168	platelet activation
0.33	GO:0009967	positive regulation of signal transduction

0.40	GO:0023027	MHC class I protein binding, via antigen binding groove
0.34	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity
0.33	GO:0005070	SH3/SH2 adaptor activity
0.33	GO:0003779	actin binding

0.87	GO:0036398	TCR signalosome
0.82	GO:0044853	plasma membrane raft
0.74	GO:0005911	cell-cell junction
0.67	GO:0005829	cytosol
0.33	GO:0036464	cytoplasmic ribonucleoprotein granule
0.30	GO:0016021	integral component of membrane

sp|Q13098|CSN1_HUMAN
COP9 signalosome complex subunit 1
Search

GPS1

0.89	G protein pathway suppressor 1

0.84	GO:0000338	protein deneddylation
0.35	GO:0034260	negative regulation of GTPase activity
0.35	GO:0007254	JNK cascade
0.35	GO:0000188	inactivation of MAPK activity
0.34	GO:0043687	post-translational protein modification
0.34	GO:0000715	nucleotide-excision repair, DNA damage recognition
0.34	GO:0006283	transcription-coupled nucleotide-excision repair

0.35	GO:0005095	GTPase inhibitor activity
0.35	GO:0005515	protein binding

0.81	GO:0008180	COP9 signalosome
0.33	GO:0005654	nucleoplasm
0.33	GO:0005829	cytosol

sp|Q13099|IFT88_HUMAN
Intraflagellar transport protein 88 homolog
Search

IFT88

0.94	LOW QUALITY PROTEIN: intraflagellar transport protein 88 homolog

0.49	GO:0060785	regulation of apoptosis involved in tissue homeostasis
0.48	GO:0060122	inner ear receptor cell stereocilium organization
0.48	GO:0072019	proximal convoluted tubule development
0.48	GO:0008589	regulation of smoothened signaling pathway
0.48	GO:1905515	non-motile cilium assembly
0.47	GO:0007368	determination of left/right symmetry
0.47	GO:0003351	epithelial cilium movement
0.46	GO:0042073	intraciliary transport
0.46	GO:0045494	photoreceptor cell maintenance
0.46	GO:0001654	eye development

0.39

GO:0019894

kinesin binding

0.74	GO:0005929	cilium
0.55	GO:0120038	plasma membrane bounded cell projection part
0.55	GO:0005815	microtubule organizing center
0.45	GO:0099568	cytoplasmic region
0.40	GO:0030992	intraciliary transport particle B
0.39	GO:0002080	acrosomal membrane
0.39	GO:0032421	stereocilium bundle
0.38	GO:0043005	neuron projection
0.37	GO:0005802	trans-Golgi network
0.36	GO:0098589	membrane region

sp|Q13103|SPP24_HUMAN
Secreted phosphoprotein 24
Search

SPP2

0.96	Transient receptor potential cation channel subfamily M member 8

0.85	GO:0046849	bone remodeling
0.40	GO:0002576	platelet degranulation
0.38	GO:0043687	post-translational protein modification
0.38	GO:0001501	skeletal system development
0.37	GO:0010951	negative regulation of endopeptidase activity
0.35	GO:0006461	protein complex assembly
0.35	GO:0016048	detection of temperature stimulus
0.35	GO:0050951	sensory perception of temperature stimulus
0.33	GO:0006812	cation transport

0.38

GO:0004866

endopeptidase inhibitor activity

0.66	GO:0005576	extracellular region
0.41	GO:0031089	platelet dense granule lumen
0.39	GO:0005788	endoplasmic reticulum lumen
0.34	GO:0043234	protein complex
0.30	GO:0016020	membrane

sp|Q13105|ZBT17_HUMAN
Zinc finger and BTB domain-containing protein 17
Search

ZBTB17

0.71	Zinc finger and BTB domain-containing protein 17

0.56	GO:0007398	ectoderm development
0.56	GO:0071158	positive regulation of cell cycle arrest
0.56	GO:0001702	gastrulation with mouth forming second
0.55	GO:1903146	regulation of autophagy of mitochondrion
0.55	GO:1903955	positive regulation of protein targeting to mitochondrion
0.52	GO:0008285	negative regulation of cell proliferation
0.50	GO:0006366	transcription by RNA polymerase II
0.50	GO:0045944	positive regulation of transcription by RNA polymerase II
0.35	GO:0030097	hemopoiesis
0.34	GO:0000398	mRNA splicing, via spliceosome

0.57	GO:0001223	transcription coactivator binding
0.54	GO:0001047	core promoter binding
0.53	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.52	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.35	GO:0046872	metal ion binding

0.49	GO:0032993	protein-DNA complex
0.44	GO:0005634	nucleus
0.43	GO:0043234	protein complex
0.32	GO:0005856	cytoskeleton
0.30	GO:0016020	membrane
0.30	GO:0043233	organelle lumen
0.30	GO:0044446	intracellular organelle part

sp|Q13106|ZN154_HUMAN
Zinc finger protein 154
Search

0.79	Zinc finger protein 154

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.41	GO:1902679	negative regulation of RNA biosynthetic process
0.38	GO:0006351	transcription, DNA-templated

0.53	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.36	GO:0005515	protein binding
0.35	GO:0003700	DNA binding transcription factor activity

0.44	GO:0005622	intracellular
0.40	GO:0043227	membrane-bounded organelle
0.30	GO:0016020	membrane

sp|Q13107|UBP4_HUMAN
Ubiquitin carboxyl-terminal hydrolase 4
Search

USP4

0.93	Ubiquitin carboxyl-terminal hydrolase 4

0.75	GO:0016579	protein deubiquitination
0.72	GO:0006511	ubiquitin-dependent protein catabolic process
0.60	GO:0034394	protein localization to cell surface
0.59	GO:0000244	spliceosomal tri-snRNP complex assembly
0.59	GO:0031397	negative regulation of protein ubiquitination
0.55	GO:0031647	regulation of protein stability
0.44	GO:0034122	negative regulation of toll-like receptor signaling pathway
0.34	GO:0000266	mitochondrial fission
0.34	GO:0007283	spermatogenesis

0.77	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.62	GO:0031685	adenosine receptor binding
0.52	GO:0042802	identical protein binding
0.35	GO:0046872	metal ion binding

0.50	GO:0005829	cytosol
0.47	GO:0005634	nucleus
0.44	GO:0005886	plasma membrane
0.35	GO:0005764	lysosome

sp|Q13111|CAF1A_HUMAN
Chromatin assembly factor 1 subunit A
Search

CHAF1A

0.93	Chromatin assembly factor 1 subunit A-B

0.85	GO:0006335	DNA replication-dependent nucleosome assembly
0.44	GO:0007049	cell cycle
0.44	GO:0006260	DNA replication
0.44	GO:0006281	DNA repair
0.36	GO:0009934	regulation of meristem structural organization
0.36	GO:0031507	heterochromatin assembly
0.36	GO:0010026	trichome differentiation
0.35	GO:0048366	leaf development
0.35	GO:0009555	pollen development
0.35	GO:0008283	cell proliferation

0.85	GO:0070087	chromo shadow domain binding
0.71	GO:0042802	identical protein binding
0.40	GO:0003682	chromatin binding
0.39	GO:0051082	unfolded protein binding
0.34	GO:0051213	dioxygenase activity

0.86	GO:0033186	CAF-1 complex
0.72	GO:0000790	nuclear chromatin
0.30	GO:0016020	membrane

sp|Q13112|CAF1B_HUMAN
Chromatin assembly factor 1 subunit B
Search

CHAF1B

0.89	LOW QUALITY PROTEIN: chromatin assembly factor 1 subunit B

0.82	GO:0006335	DNA replication-dependent nucleosome assembly
0.53	GO:0060041	retina development in camera-type eye
0.51	GO:0048568	embryonic organ development
0.49	GO:0000278	mitotic cell cycle
0.40	GO:0006260	DNA replication
0.39	GO:0006281	DNA repair
0.37	GO:0006351	transcription, DNA-templated
0.37	GO:1903506	regulation of nucleic acid-templated transcription
0.37	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.37	GO:0010468	regulation of gene expression

0.59	GO:0042393	histone binding
0.38	GO:0003682	chromatin binding
0.37	GO:0051082	unfolded protein binding

0.85	GO:0033186	CAF-1 complex
0.69	GO:0000790	nuclear chromatin
0.65	GO:0005654	nucleoplasm
0.39	GO:0005829	cytosol

sp|Q13113|PDZ1I_HUMAN
PDZK1-interacting protein 1
Search

PDZK1IP1

0.97	PDZK1-interacting protein 1

0.35

GO:0046983

protein dimerization activity

0.39	GO:0070062	extracellular exosome
0.30	GO:0044425	membrane part

sp|Q13114|TRAF3_HUMAN
TNF receptor-associated factor 3
Search

TRAF3

0.96	TNF receptor-associated factor 3

0.85	GO:0008063	Toll signaling pathway
0.85	GO:0033209	tumor necrosis factor-mediated signaling pathway
0.85	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.85	GO:0050688	regulation of defense response to virus
0.79	GO:0001817	regulation of cytokine production
0.79	GO:0045087	innate immune response
0.73	GO:0042981	regulation of apoptotic process
0.55	GO:0002224	toll-like receptor signaling pathway
0.51	GO:0030162	regulation of proteolysis
0.42	GO:0001878	response to yeast

0.84	GO:0005164	tumor necrosis factor receptor binding
0.63	GO:0008270	zinc ion binding
0.59	GO:0031996	thioesterase binding
0.56	GO:0019903	protein phosphatase binding
0.54	GO:0031625	ubiquitin protein ligase binding
0.53	GO:0019901	protein kinase binding
0.34	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0004871	signal transducer activity

0.59	GO:0035631	CD40 receptor complex
0.52	GO:0009898	cytoplasmic side of plasma membrane
0.36	GO:0005768	endosome
0.34	GO:0005829	cytosol
0.33	GO:0005739	mitochondrion

0.34

GO:0004842

sp|Q13115|DUS4_HUMAN
Dual specificity protein phosphatase 4
Search

DUSP4

0.72	Dual specificity protein phosphatase

0.85	GO:0000188	inactivation of MAPK activity
0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.58	GO:0035970	peptidyl-threonine dephosphorylation
0.57	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.55	GO:0001706	endoderm formation
0.42	GO:0060795	cell fate commitment involved in formation of primary germ layer
0.42	GO:0001708	cell fate specification
0.40	GO:0042981	regulation of apoptotic process
0.38	GO:0033574	response to testosterone
0.38	GO:0032355	response to estradiol

0.85	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity
0.74	GO:0004725	protein tyrosine phosphatase activity
0.61	GO:0008330	protein tyrosine/threonine phosphatase activity
0.59	GO:1990439	MAP kinase serine/threonine phosphatase activity
0.37	GO:0019838	growth factor binding
0.33	GO:0016301	kinase activity

0.48	GO:0005654	nucleoplasm
0.36	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.85

GO:0017017

sp|Q13117|DAZ2_HUMAN
Deleted in azoospermia protein 2
Search

0.84	Deleted in azoospermia protein 2

0.79	GO:0007281	germ cell development
0.71	GO:0045727	positive regulation of translation
0.48	GO:0006446	regulation of translational initiation
0.47	GO:0007292	female gamete generation
0.46	GO:0070935	3'-UTR-mediated mRNA stabilization
0.45	GO:0045836	positive regulation of meiotic nuclear division
0.44	GO:0007135	meiosis II
0.44	GO:0071695	anatomical structure maturation
0.43	GO:0048469	cell maturation
0.40	GO:0007283	spermatogenesis

0.83	GO:0008494	translation activator activity
0.80	GO:0003730	mRNA 3'-UTR binding
0.41	GO:0042802	identical protein binding
0.33	GO:0043565	sequence-specific DNA binding

0.43	GO:0005844	polysome
0.41	GO:0032019	mitochondrial cloud
0.38	GO:0045495	pole plasm
0.32	GO:0043234	protein complex
0.30	GO:0043227	membrane-bounded organelle

sp|Q13118|KLF10_HUMAN
Krueppel-like factor 10
Search

KLF10

0.97	Kruppel like factor 10

0.63	GO:0045672	positive regulation of osteoclast differentiation
0.62	GO:0030282	bone mineralization
0.62	GO:0035019	somatic stem cell population maintenance
0.59	GO:0007623	circadian rhythm
0.57	GO:0009267	cellular response to starvation
0.56	GO:0006366	transcription by RNA polymerase II
0.55	GO:0045944	positive regulation of transcription by RNA polymerase II
0.54	GO:0045892	negative regulation of transcription, DNA-templated
0.40	GO:0042752	regulation of circadian rhythm
0.40	GO:1901653	cellular response to peptide

0.60	GO:0001046	core promoter sequence-specific DNA binding
0.59	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.58	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.35	GO:0005515	protein binding
0.35	GO:0046872	metal ion binding

0.48	GO:0005634	nucleus
0.37	GO:0005925	focal adhesion
0.36	GO:0005829	cytosol
0.35	GO:0043233	organelle lumen
0.34	GO:0044446	intracellular organelle part

sp|Q13123|RED_HUMAN
Protein Red
Search

0.97	IK cytokine, down-regulator of HLA II

0.55	GO:0034501	protein localization to kinetochore
0.53	GO:0007094	mitotic spindle assembly checkpoint
0.41	GO:0060047	heart contraction
0.39	GO:0008380	RNA splicing
0.38	GO:0006397	mRNA processing
0.34	GO:0016032	viral process
0.33	GO:0042273	ribosomal large subunit biogenesis
0.32	GO:0006364	rRNA processing

0.49

GO:0042802

identical protein binding

0.61	GO:0005634	nucleus
0.55	GO:0097431	mitotic spindle pole
0.47	GO:0005694	chromosome
0.46	GO:0031974	membrane-enclosed lumen
0.36	GO:0030529	intracellular ribonucleoprotein complex
0.34	GO:0005737	cytoplasm

sp|Q13126|MTAP_HUMAN
S-methyl-5'-thioadenosine phosphorylase
Search

MTAP

0.53	Purine nucleoside phosphorylase

0.70	GO:0006166	purine ribonucleoside salvage
0.69	GO:0019509	L-methionine salvage from methylthioadenosine
0.41	GO:0032259	methylation
0.38	GO:0070638	pyridine nucleoside catabolic process
0.37	GO:0046495	nicotinamide riboside metabolic process
0.36	GO:0035722	interleukin-12-mediated signaling pathway
0.35	GO:0033574	response to testosterone

0.81	GO:0017061	S-methyl-5-thioadenosine phosphorylase activity
0.34	GO:0004645	phosphorylase activity
0.33	GO:0005515	protein binding

0.57	GO:0005634	nucleus
0.46	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.81

EC:2.4.2.28

GO:0017061

sp|Q13127|REST_HUMAN
RE1-silencing transcription factor
Search

REST

0.79	Neural-restrictive silencer factor

0.84	GO:0045665	negative regulation of neuron differentiation
0.79	GO:0043065	positive regulation of apoptotic process
0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.64	GO:2000797	regulation of amniotic stem cell differentiation
0.64	GO:2000740	negative regulation of mesenchymal stem cell differentiation
0.63	GO:0032345	negative regulation of aldosterone metabolic process
0.63	GO:2000065	negative regulation of cortisol biosynthetic process
0.62	GO:0032347	regulation of aldosterone biosynthetic process
0.62	GO:0071257	cellular response to electrical stimulus
0.61	GO:0043922	negative regulation by host of viral transcription

0.73	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.61	GO:0015271	outward rectifier potassium channel activity
0.58	GO:0001046	core promoter sequence-specific DNA binding
0.53	GO:0003682	chromatin binding
0.52	GO:0008134	transcription factor binding
0.39	GO:0004407	histone deacetylase activity
0.37	GO:0046872	metal ion binding
0.35	GO:0032403	protein complex binding

0.61	GO:0005634	nucleus
0.56	GO:0017053	transcriptional repressor complex
0.49	GO:0005829	cytosol
0.37	GO:0070013	intracellular organelle lumen
0.36	GO:0044446	intracellular organelle part
0.34	GO:0005694	chromosome
0.34	GO:0043234	protein complex
0.32	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.31	GO:0005783	endoplasmic reticulum
0.30	GO:0016021	integral component of membrane

0.39

EC:3.5.1.98

GO:0004407

sp|Q13129|RLF_HUMAN
Zinc finger protein Rlf
Search

RLF

0.96	Zinc finger protein Rlf

0.68	GO:0097692	histone H3-K4 monomethylation
0.64	GO:0044030	regulation of DNA methylation
0.54	GO:0015074	DNA integration
0.37	GO:0045944	positive regulation of transcription by RNA polymerase II
0.34	GO:0006351	transcription, DNA-templated
0.33	GO:0071586	CAAX-box protein processing

0.51	GO:0003676	nucleic acid binding
0.35	GO:0005515	protein binding
0.34	GO:0008270	zinc ion binding
0.34	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.32	GO:0004222	metalloendopeptidase activity

0.36	GO:0070062	extracellular exosome
0.35	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0004222

sp|Q13131|AAPK1_HUMAN
5'-AMP-activated protein kinase catalytic subunit alpha-1
Search

PRKAA1

0.58	Non-specific serine/threonine protein kinase

0.63	GO:0006468	protein phosphorylation
0.60	GO:0071380	cellular response to prostaglandin E stimulus
0.58	GO:0042149	cellular response to glucose starvation
0.58	GO:0032007	negative regulation of TOR signaling
0.57	GO:0042752	regulation of circadian rhythm
0.57	GO:0061762	CAMKK-AMPK signaling cascade
0.56	GO:0018209	peptidyl-serine modification
0.56	GO:1901563	response to camptothecin
0.56	GO:0042593	glucose homeostasis
0.55	GO:0010508	positive regulation of autophagy

0.70	GO:0004674	protein serine/threonine kinase activity
0.60	GO:0035173	histone kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0003682	chromatin binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0060089	molecular transducer activity
0.44	GO:0050405	[acetyl-CoA carboxylase] kinase activity
0.44	GO:0004712	protein serine/threonine/tyrosine kinase activity

0.55	GO:0016607	nuclear speck
0.47	GO:0005829	cytosol
0.44	GO:0031588	nucleotide-activated protein kinase complex
0.41	GO:0005794	Golgi apparatus
0.38	GO:0016324	apical plasma membrane
0.33	GO:0005840	ribosome
0.30	GO:0016021	integral component of membrane

0.70

GO:0004674

sp|Q13133|NR1H3_HUMAN
Oxysterols receptor LXR-alpha
Search

NR1H3

0.96	Oxysterols receptor LXR-alpha

0.78	GO:0043401	steroid hormone mediated signaling pathway
0.59	GO:0090341	negative regulation of secretion of lysosomal enzymes
0.58	GO:0010887	negative regulation of cholesterol storage
0.58	GO:0097659	nucleic acid-templated transcription
0.58	GO:0090186	regulation of pancreatic juice secretion
0.57	GO:2000188	regulation of cholesterol homeostasis
0.57	GO:0010875	positive regulation of cholesterol efflux
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:0060457	negative regulation of digestive system process

0.79	GO:0003707	steroid hormone receptor activity
0.65	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.51	GO:0001012	RNA polymerase II regulatory region DNA binding
0.49	GO:0003690	double-stranded DNA binding
0.40	GO:0046965	retinoid X receptor binding
0.36	GO:0102009	proline dipeptidase activity
0.35	GO:0015485	cholesterol binding
0.35	GO:0034191	apolipoprotein A-I receptor binding

0.61	GO:0005634	nucleus
0.50	GO:0005667	transcription factor complex
0.42	GO:0044446	intracellular organelle part
0.37	GO:0043235	receptor complex
0.36	GO:0005694	chromosome
0.36	GO:0070013	intracellular organelle lumen
0.32	GO:0005737	cytoplasm

0.36

EC:3.4.13.9

GO:0102009

sp|Q13136|LIPA1_HUMAN
Liprin-alpha-1
Search

PPFIA1

0.94	PTPRF interacting protein alpha 1

0.85	GO:0051497	negative regulation of stress fiber assembly
0.85	GO:1903077	negative regulation of protein localization to plasma membrane
0.50	GO:0014047	glutamate secretion
0.47	GO:0099643	signal release from synapse
0.47	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.47	GO:0007160	cell-matrix adhesion
0.45	GO:0006836	neurotransmitter transport
0.43	GO:0001505	regulation of neurotransmitter levels
0.42	GO:0051649	establishment of localization in cell
0.40	GO:0007165	signal transduction

0.47	GO:0005515	protein binding
0.41	GO:0004871	signal transducer activity
0.36	GO:0008308	voltage-gated anion channel activity

0.71	GO:0005925	focal adhesion
0.61	GO:0005829	cytosol
0.57	GO:0097458	neuron part
0.53	GO:0120038	plasma membrane bounded cell projection part
0.45	GO:0043234	protein complex
0.45	GO:0044456	synapse part
0.35	GO:0005741	mitochondrial outer membrane
0.30	GO:0016021	integral component of membrane

sp|Q13137|CACO2_HUMAN
Calcium-binding and coiled-coil domain-containing protein 2
Search

CALCOCO2

0.95	Calcium-binding and coiled-coil domain-containing protein 2

0.86	GO:0098792	xenophagy
0.86	GO:1901098	positive regulation of autophagosome maturation
0.80	GO:0034341	response to interferon-gamma
0.38	GO:0016032	viral process
0.38	GO:0015991	ATP hydrolysis coupled proton transport
0.37	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.37	GO:0006754	ATP biosynthetic process

0.71	GO:0042803	protein homodimerization activity
0.36	GO:0015078	hydrogen ion transmembrane transporter activity
0.35	GO:0003676	nucleic acid binding

0.82	GO:0005776	autophagosome
0.77	GO:0048471	perinuclear region of cytoplasm
0.66	GO:0005829	cytosol
0.50	GO:0005774	vacuolar membrane
0.48	GO:0031410	cytoplasmic vesicle
0.47	GO:0005856	cytoskeleton
0.39	GO:0005634	nucleus
0.37	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)
0.36	GO:0005794	Golgi apparatus
0.35	GO:0043233	organelle lumen

sp|Q13144|EI2BE_HUMAN
Translation initiation factor eIF-2B subunit epsilon
Search

EIF2B5

0.91	Eukaryotic translation initiation factor 2B subunit epsilon

0.68	GO:0006413	translational initiation
0.60	GO:1904628	cellular response to phorbol 13-acetate 12-myristate
0.59	GO:0014002	astrocyte development
0.59	GO:0014003	oligodendrocyte development
0.57	GO:0001541	ovarian follicle development
0.57	GO:0042552	myelination
0.55	GO:0034976	response to endoplasmic reticulum stress
0.53	GO:0009408	response to heat
0.48	GO:0065009	regulation of molecular function
0.40	GO:0009749	response to glucose

0.69	GO:0003743	translation initiation factor activity
0.53	GO:0005085	guanyl-nucleotide exchange factor activity
0.42	GO:0016779	nucleotidyltransferase activity
0.39	GO:0031369	translation initiation factor binding

0.58	GO:0005851	eukaryotic translation initiation factor 2B complex
0.49	GO:0005829	cytosol
0.45	GO:0005634	nucleus

0.42

GO:0016779

sp|Q13145|BAMBI_HUMAN
BMP and activin membrane-bound inhibitor homolog
Search

BAMBI

0.97	BMP and activin membrane-bound inhibitor

0.84	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.84	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.59	GO:0035413	positive regulation of catenin import into nucleus
0.57	GO:0010718	positive regulation of epithelial to mesenchymal transition
0.56	GO:0032092	positive regulation of protein binding
0.53	GO:0008284	positive regulation of cell proliferation
0.53	GO:0016477	cell migration
0.50	GO:0045893	positive regulation of transcription, DNA-templated
0.49	GO:0008360	regulation of cell shape
0.37	GO:0030514	negative regulation of BMP signaling pathway

0.57	GO:0005109	frizzled binding
0.36	GO:0005114	type II transforming growth factor beta receptor binding

0.42	GO:0005886	plasma membrane
0.39	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

sp|Q13148|TADBP_HUMAN
TAR DNA-binding protein 43
Search

TARDBP

0.91	TAR DNA binding protein, like

0.51	GO:0071765	nuclear inner membrane organization
0.49	GO:0043922	negative regulation by host of viral transcription
0.49	GO:0070935	3'-UTR-mediated mRNA stabilization
0.47	GO:0006366	transcription by RNA polymerase II
0.47	GO:0045944	positive regulation of transcription by RNA polymerase II
0.45	GO:0008380	RNA splicing
0.44	GO:0001933	negative regulation of protein phosphorylation
0.44	GO:0042981	regulation of apoptotic process
0.44	GO:0051726	regulation of cell cycle
0.42	GO:0010629	negative regulation of gene expression

0.57	GO:0003723	RNA binding
0.52	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding
0.48	GO:0003677	DNA binding
0.44	GO:0042802	identical protein binding

0.43

GO:0005654

nucleoplasm

sp|Q13151|ROA0_HUMAN
Heterogeneous nuclear ribonucleoprotein A0
Search

HNRNPA0

0.88	Heterogeneous nuclear ribonucleoprotein A0

0.54	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.52	GO:0051028	mRNA transport
0.51	GO:0006405	RNA export from nucleus
0.49	GO:0006397	mRNA processing
0.47	GO:0070935	3'-UTR-mediated mRNA stabilization
0.45	GO:0032496	response to lipopolysaccharide
0.44	GO:0006954	inflammatory response
0.43	GO:1990428	miRNA transport
0.42	GO:0031053	primary miRNA processing
0.41	GO:0048025	negative regulation of mRNA splicing, via spliceosome

0.59	GO:0003723	RNA binding
0.49	GO:0019901	protein kinase binding
0.41	GO:0043047	single-stranded telomeric DNA binding
0.33	GO:0042802	identical protein binding
0.32	GO:0051032	nucleic acid transmembrane transporter activity
0.32	GO:0008241	peptidyl-dipeptidase activity
0.32	GO:0004180	carboxypeptidase activity
0.32	GO:0008237	metallopeptidase activity
0.31	GO:0046872	metal ion binding

0.55	GO:0019013	viral nucleocapsid
0.51	GO:0030529	intracellular ribonucleoprotein complex
0.48	GO:0005654	nucleoplasm
0.40	GO:0070062	extracellular exosome
0.37	GO:1902494	catalytic complex
0.35	GO:0005737	cytoplasm
0.32	GO:0043005	neuron projection
0.31	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

0.32

EC:3.4.15

GO:0008241

sp|Q13153|PAK1_HUMAN
Serine/threonine-protein kinase PAK 1
Search

PAK1

0.91	p21 protein-activated kinase 1 (Fragment)

0.68	GO:0060244	negative regulation of cell proliferation involved in contact inhibition
0.67	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway
0.66	GO:0048012	hepatocyte growth factor receptor signaling pathway
0.64	GO:0051496	positive regulation of stress fiber assembly
0.64	GO:0045860	positive regulation of protein kinase activity
0.64	GO:0043408	regulation of MAPK cascade
0.63	GO:0031116	positive regulation of microtubule polymerization
0.63	GO:0006468	protein phosphorylation
0.63	GO:0033138	positive regulation of peptidyl-serine phosphorylation
0.62	GO:0048754	branching morphogenesis of an epithelial tube

0.70	GO:0004674	protein serine/threonine kinase activity
0.62	GO:0005518	collagen binding
0.55	GO:0048365	Rac GTPase binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0004708	MAP kinase kinase activity
0.41	GO:0042802	identical protein binding
0.39	GO:0046983	protein dimerization activity

0.65	GO:0071437	invadopodium
0.62	GO:0001726	ruffle
0.58	GO:0005911	cell-cell junction
0.53	GO:0005829	cytosol
0.47	GO:0043234	protein complex
0.45	GO:0005886	plasma membrane

0.70

GO:0004674

sp|Q13155|AIMP2_HUMAN
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2
Search

AIMP2

0.97	Aminoacyl tRNA synthetase complex interacting multifunctional protein 2

0.86	GO:1903632	positive regulation of aminoacyl-tRNA ligase activity
0.85	GO:0060510	Type II pneumocyte differentiation
0.76	GO:0031398	positive regulation of protein ubiquitination
0.74	GO:0008285	negative regulation of cell proliferation
0.65	GO:0006461	protein complex assembly
0.48	GO:1901216	positive regulation of neuron death
0.47	GO:0006915	apoptotic process
0.41	GO:0043043	peptide biosynthetic process
0.39	GO:0044267	cellular protein metabolic process
0.38	GO:0010467	gene expression

0.76	GO:0032947	protein complex scaffold activity
0.46	GO:0004812	aminoacyl-tRNA ligase activity
0.35	GO:0005509	calcium ion binding
0.32	GO:0016740	transferase activity

0.82	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex
0.63	GO:0005829	cytosol
0.58	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.46

EC:6.1.1

GO:0004812

sp|Q13156|RFA4_HUMAN
Replication protein A 30 kDa subunit
Search

RPA2

0.75	Replication protein A2

0.79	GO:2000001	regulation of DNA damage checkpoint
0.78	GO:0010569	regulation of double-strand break repair via homologous recombination
0.78	GO:0031571	mitotic G1 DNA damage checkpoint
0.75	GO:0034502	protein localization to chromosome
0.71	GO:0000723	telomere maintenance
0.69	GO:0000724	double-strand break repair via homologous recombination
0.68	GO:0006298	mismatch repair
0.66	GO:0006260	DNA replication
0.66	GO:0006284	base-excision repair
0.66	GO:0006289	nucleotide-excision repair

0.81	GO:0098505	G-rich strand telomeric DNA binding
0.75	GO:0019903	protein phosphatase binding
0.71	GO:0031625	ubiquitin protein ligase binding
0.66	GO:0003684	damaged DNA binding

0.78	GO:0005662	DNA replication factor A complex
0.76	GO:0016605	PML body
0.75	GO:0035861	site of double-strand break
0.71	GO:0000781	chromosome, telomeric region
0.65	GO:0000785	chromatin

sp|Q13158|FADD_HUMAN
FAS-associated death domain protein
Search

FADD

0.97	Fas associated via death domain

0.85	GO:2000454	positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation
0.84	GO:0070236	negative regulation of activation-induced cell death of T cells
0.82	GO:0002821	positive regulation of adaptive immune response
0.81	GO:0001914	regulation of T cell mediated cytotoxicity
0.80	GO:0048535	lymph node development
0.80	GO:0042104	positive regulation of activated T cell proliferation
0.79	GO:0001912	positive regulation of leukocyte mediated cytotoxicity
0.79	GO:0048536	spleen development
0.79	GO:0043029	T cell homeostasis
0.78	GO:0033077	T cell differentiation in thymus

0.77	GO:0035877	death effector domain binding
0.76	GO:0089720	caspase binding
0.70	GO:0032813	tumor necrosis factor receptor superfamily binding
0.63	GO:0042802	identical protein binding
0.47	GO:0033612	receptor serine/threonine kinase binding
0.43	GO:0032403	protein complex binding

0.82	GO:0097342	ripoptosome
0.77	GO:0031265	CD95 death-inducing signaling complex
0.45	GO:0044297	cell body
0.45	GO:0098857	membrane microdomain
0.44	GO:0043005	neuron projection
0.39	GO:0005634	nucleus

sp|Q13162|PRDX4_HUMAN
Peroxiredoxin-4
Search

PRDX4

0.43	Epididymis secretory sperm binding protein Li 97n

0.69	GO:0098869	cellular oxidant detoxification
0.69	GO:0045454	cell redox homeostasis
0.58	GO:2000255	negative regulation of male germ cell proliferation
0.57	GO:0022417	protein maturation by protein folding
0.57	GO:0019471	4-hydroxyproline metabolic process
0.54	GO:0008584	male gonad development
0.53	GO:0055114	oxidation-reduction process
0.52	GO:0030198	extracellular matrix organization
0.52	GO:0007283	spermatogenesis
0.49	GO:0072593	reactive oxygen species metabolic process

0.73	GO:0051920	peroxiredoxin activity
0.50	GO:0042803	protein homodimerization activity
0.41	GO:0004601	peroxidase activity
0.34	GO:0004867	serine-type endopeptidase inhibitor activity

0.48	GO:0005783	endoplasmic reticulum
0.47	GO:0005829	cytosol
0.43	GO:0005739	mitochondrion
0.37	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.36	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen
0.34	GO:0005634	nucleus

0.73	EC:1.11.1.15	GO:0051920
0.41	KEGG:R03532	GO:0004601

sp|Q13163|MP2K5_HUMAN
Dual specificity mitogen-activated protein kinase kinase 5
Search

MAP2K5

0.97	Dual specificity mitogen-activated protein kinase kinase 5

0.63	GO:0006468	protein phosphorylation
0.55	GO:0048513	animal organ development
0.54	GO:0072359	circulatory system development
0.48	GO:0031098	stress-activated protein kinase signaling cascade
0.48	GO:0032147	activation of protein kinase activity
0.46	GO:0007346	regulation of mitotic cell cycle
0.46	GO:0042981	regulation of apoptotic process
0.44	GO:0060322	head development
0.44	GO:0007417	central nervous system development
0.42	GO:2000342	negative regulation of chemokine (C-X-C motif) ligand 2 production

0.67	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0004713	protein tyrosine kinase activity
0.35	GO:0004708	MAP kinase kinase activity
0.35	GO:0005515	protein binding
0.35	GO:0005057	signal transducer activity, downstream of receptor
0.34	GO:0046872	metal ion binding
0.33	GO:0003714	transcription corepressor activity

0.53	GO:0005819	spindle
0.37	GO:0005829	cytosol
0.36	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.67

GO:0004674

sp|Q13164|MK07_HUMAN
Mitogen-activated protein kinase 7
Search

MAPK7

0.50	Mitogen-activated protein kinase

0.76	GO:0000165	MAPK cascade
0.66	GO:0070377	negative regulation of ERK5 cascade
0.64	GO:0051534	negative regulation of NFAT protein import into nucleus
0.63	GO:0071499	cellular response to laminar fluid shear stress
0.63	GO:0034115	negative regulation of heterotypic cell-cell adhesion
0.62	GO:1902176	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
0.61	GO:2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
0.61	GO:2000352	negative regulation of endothelial cell apoptotic process
0.60	GO:0070301	cellular response to hydrogen peroxide
0.60	GO:0036003	positive regulation of transcription from RNA polymerase II promoter in response to stress

0.78	GO:0004707	MAP kinase activity
0.62	GO:0051019	mitogen-activated protein kinase binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity
0.32	GO:0003677	DNA binding

0.59	GO:0016605	PML body
0.51	GO:0005829	cytosol
0.36	GO:0030128	clathrin coat of endocytic vesicle
0.30	GO:0016021	integral component of membrane

0.78	EC:2.7.11.24	GO:0004707
0.78	KEGG:R00162	GO:0004707

sp|Q13166|CATR1_HUMAN
CATR tumorigenic conversion 1 protein
Search

0.37	CATR tumorigenic conversion 1 protein

sp|Q13177|PAK2_HUMAN
Serine/threonine-protein kinase PAK 2
Search

PAK2

0.94	Serine-threonine-protein kinase PAK 2

0.69	GO:0042981	regulation of apoptotic process
0.63	GO:0006468	protein phosphorylation
0.51	GO:0061098	positive regulation of protein tyrosine kinase activity
0.51	GO:0060996	dendritic spine development
0.51	GO:2000117	negative regulation of cysteine-type endopeptidase activity
0.50	GO:0018209	peptidyl-serine modification
0.49	GO:0043068	positive regulation of programmed cell death
0.48	GO:0043069	negative regulation of programmed cell death
0.48	GO:0009967	positive regulation of signal transduction
0.47	GO:0071407	cellular response to organic cyclic compound

0.70	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0030296	protein tyrosine kinase activator activity
0.52	GO:0048365	Rac GTPase binding
0.50	GO:0045296	cadherin binding
0.49	GO:0019901	protein kinase binding
0.47	GO:0042802	identical protein binding

0.45	GO:0005829	cytosol
0.42	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0005634	nucleus
0.38	GO:0012505	endomembrane system
0.36	GO:0031984	organelle subcompartment
0.36	GO:0099503	secretory vesicle
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

0.70

GO:0004674

sp|Q13183|S13A2_HUMAN
Solute carrier family 13 member 2
Search

SLC13A2

0.94	Solute carrier family 13 (Sodium-dependent dicarboxylate transporter), member 2

0.71	GO:0006814	sodium ion transport
0.54	GO:0055085	transmembrane transport
0.42	GO:0006820	anion transport
0.38	GO:0015849	organic acid transport
0.35	GO:0015893	drug transport

0.55

GO:0005215

transporter activity

0.42	GO:0005887	integral component of plasma membrane
0.37	GO:0070062	extracellular exosome

sp|Q13185|CBX3_HUMAN
Chromobox protein homolog 3
Search

CBX3

0.95	Chromobox protein like protein 3

0.72	GO:0045892	negative regulation of transcription, DNA-templated
0.38	GO:0071549	cellular response to dexamethasone stimulus
0.37	GO:0048511	rhythmic process
0.36	GO:0016569	covalent chromatin modification
0.35	GO:0070317	negative regulation of G0 to G1 transition
0.35	GO:0006351	transcription, DNA-templated
0.34	GO:0006338	chromatin remodeling

0.48	GO:1990226	histone methyltransferase binding
0.45	GO:0019904	protein domain specific binding
0.43	GO:0042802	identical protein binding
0.36	GO:0000976	transcription regulatory region sequence-specific DNA binding

0.85	GO:0005719	nuclear euchromatin
0.47	GO:0005720	nuclear heterochromatin
0.45	GO:0000775	chromosome, centromeric region
0.45	GO:0005819	spindle
0.39	GO:0000793	condensed chromosome
0.39	GO:0005635	nuclear envelope
0.39	GO:0035985	senescence-associated heterochromatin focus
0.37	GO:0010369	chromocenter
0.36	GO:0000784	nuclear chromosome, telomeric region
0.35	GO:0005654	nucleoplasm

sp|Q13188|STK3_HUMAN
Serine/threonine-protein kinase 3
Search

STK3

0.92	Serine/threonine-protein kinase 3

0.63	GO:0060800	regulation of cell differentiation involved in embryonic placenta development
0.62	GO:0097284	hepatocyte apoptotic process
0.62	GO:0006468	protein phosphorylation
0.62	GO:0035329	hippo signaling
0.62	GO:0003157	endocardium development
0.62	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.61	GO:0060215	primitive hemopoiesis
0.61	GO:0046621	negative regulation of organ growth
0.60	GO:0045600	positive regulation of fat cell differentiation
0.60	GO:0032092	positive regulation of protein binding

0.67	GO:0004674	protein serine/threonine kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0042802	identical protein binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0000287	magnesium ion binding
0.45	GO:0008134	transcription factor binding
0.44	GO:0046983	protein dimerization activity
0.35	GO:0043539	protein serine/threonine kinase activator activity

0.47	GO:0016604	nuclear body
0.46	GO:0043234	protein complex
0.44	GO:0005829	cytosol

0.67

GO:0004674

sp|Q13190|STX5_HUMAN
Syntaxin-5
Search

STX5

0.86	Syntaxin-5

0.68	GO:0016192	vesicle-mediated transport
0.66	GO:0006886	intracellular protein transport
0.66	GO:0061025	membrane fusion
0.57	GO:0090166	Golgi disassembly
0.56	GO:1903358	regulation of Golgi organization
0.52	GO:0016482	cytosolic transport
0.52	GO:0045732	positive regulation of protein catabolic process
0.51	GO:0016197	endosomal transport
0.48	GO:0048284	organelle fusion
0.47	GO:0016050	vesicle organization

0.78	GO:0005484	SNAP receptor activity
0.54	GO:0047485	protein N-terminus binding
0.52	GO:0045296	cadherin binding
0.48	GO:0000149	SNARE binding

0.50	GO:0005794	Golgi apparatus
0.48	GO:0031201	SNARE complex
0.48	GO:0031982	vesicle
0.47	GO:0005829	cytosol
0.44	GO:0098588	bounding membrane of organelle
0.43	GO:0031984	organelle subcompartment
0.40	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.36	GO:0005783	endoplasmic reticulum
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0098805	whole membrane

sp|Q13191|CBLB_HUMAN
E3 ubiquitin-protein ligase CBL-B
Search

0.81	Tyrosine kinase negative regulator Cbl

0.73	GO:0016567	protein ubiquitination
0.71	GO:0007166	cell surface receptor signaling pathway
0.70	GO:0023051	regulation of signaling
0.53	GO:0061099	negative regulation of protein tyrosine kinase activity
0.48	GO:0010648	negative regulation of cell communication
0.47	GO:0048585	negative regulation of response to stimulus
0.43	GO:0006508	proteolysis
0.40	GO:0048260	positive regulation of receptor-mediated endocytosis
0.39	GO:0043066	negative regulation of apoptotic process
0.38	GO:0002376	immune system process

0.85	GO:0001784	phosphotyrosine residue binding
0.74	GO:0004842	ubiquitin-protein transferase activity
0.70	GO:0005509	calcium ion binding
0.64	GO:0004871	signal transducer activity
0.52	GO:0030971	receptor tyrosine kinase binding
0.51	GO:0016874	ligase activity
0.51	GO:0017124	SH3 domain binding
0.48	GO:0061659	ubiquitin-like protein ligase activity
0.40	GO:0046875	ephrin receptor binding
0.39	GO:0045296	cadherin binding

0.61	GO:0005634	nucleus
0.51	GO:0045121	membrane raft
0.45	GO:0005829	cytosol
0.43	GO:0031974	membrane-enclosed lumen
0.41	GO:0005886	plasma membrane
0.40	GO:0044446	intracellular organelle part
0.36	GO:0098796	membrane protein complex

0.51	EC:6	GO:0016874
0.74	KEGG:R03876	GO:0004842

sp|Q13200|PSMD2_HUMAN
26S proteasome non-ATPase regulatory subunit 2
Search

PSMD2

0.91	26S proteasome non-ATPase regulatory subunit 2

0.78	GO:0042176	regulation of protein catabolic process
0.69	GO:0050790	regulation of catalytic activity
0.45	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation
0.35	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0070498	interleukin-1-mediated signaling pathway

0.70	GO:0030234	enzyme regulator activity
0.42	GO:0004175	endopeptidase activity
0.34	GO:0005515	protein binding
0.33	GO:0008237	metallopeptidase activity

0.73	GO:1905369	endopeptidase complex
0.60	GO:0043234	protein complex
0.45	GO:0005622	intracellular
0.38	GO:0043227	membrane-bounded organelle
0.36	GO:0043230	extracellular organelle
0.35	GO:0005615	extracellular space
0.33	GO:0012505	endomembrane system
0.33	GO:0031974	membrane-enclosed lumen
0.33	GO:0044422	organelle part
0.30	GO:0016020	membrane

sp|Q13201|MMRN1_HUMAN
Multimerin-1
Search

MMRN1

0.97	Multimerin-1 isoform A

0.81	GO:0007596	blood coagulation
0.38	GO:0002576	platelet degranulation
0.36	GO:0007155	cell adhesion
0.32	GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis
0.32	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway
0.31	GO:0072376	protein activation cascade
0.31	GO:0006260	DNA replication
0.31	GO:0006468	protein phosphorylation
0.31	GO:0006351	transcription, DNA-templated
0.31	GO:1903506	regulation of nucleic acid-templated transcription

0.65	GO:0005509	calcium ion binding
0.34	GO:0005515	protein binding
0.32	GO:0030023	extracellular matrix constituent conferring elasticity
0.31	GO:0004252	serine-type endopeptidase activity
0.31	GO:0003700	DNA binding transcription factor activity
0.31	GO:0004672	protein kinase activity
0.31	GO:0003677	DNA binding
0.31	GO:0005524	ATP binding

0.47	GO:0031012	extracellular matrix
0.38	GO:0031093	platelet alpha granule lumen
0.32	GO:0005615	extracellular space
0.31	GO:0005886	plasma membrane
0.31	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.31

GO:0004252

sp|Q13202|DUS8_HUMAN
Dual specificity protein phosphatase 8
Search

DUSP8

0.92	Dual specificity protein phosphatase 8

0.84	GO:0000188	inactivation of MAPK activity
0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.35	GO:0045208	MAPK phosphatase export from nucleus
0.35	GO:0045204	MAPK export from nucleus
0.33	GO:0034397	telomere localization

0.85	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity
0.74	GO:0004725	protein tyrosine phosphatase activity

0.42	GO:0005654	nucleoplasm
0.36	GO:0005737	cytoplasm
0.33	GO:0097708	intracellular vesicle
0.30	GO:0016020	membrane

0.85

GO:0017017

sp|Q13203|MYBPH_HUMAN
Myosin-binding protein H
Search

MYBPH

0.97	Myosin binding protein H like

0.86	GO:0071688	striated muscle myosin thick filament assembly
0.85	GO:0045214	sarcomere organization
0.82	GO:0006941	striated muscle contraction
0.74	GO:0007015	actin filament organization
0.51	GO:0007155	cell adhesion
0.45	GO:0006942	regulation of striated muscle contraction

0.86	GO:0097493	structural molecule activity conferring elasticity
0.86	GO:0051371	muscle alpha-actinin binding
0.85	GO:0008307	structural constituent of muscle
0.77	GO:0051015	actin filament binding

0.86	GO:0005859	muscle myosin complex
0.85	GO:0031672	A band
0.83	GO:0030018	Z disc
0.59	GO:0032982	myosin filament

sp|Q13206|DDX10_HUMAN
Probable ATP-dependent RNA helicase DDX10
Search

DDX10

0.53	RNA helicase

0.50	GO:0010501	RNA secondary structure unwinding
0.33	GO:0015074	DNA integration

0.66	GO:0004386	helicase activity
0.58	GO:0003723	RNA binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0008186	RNA-dependent ATPase activity
0.42	GO:0140098	catalytic activity, acting on RNA

0.47	GO:0005730	nucleolus
0.37	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

sp|Q13207|TBX2_HUMAN
T-box transcription factor TBX2
Search

TBX2

0.95

T-box 2

0.84	GO:1901211	negative regulation of cardiac chamber formation
0.84	GO:1901208	negative regulation of heart looping
0.81	GO:0007521	muscle cell fate determination
0.80	GO:0060596	mammary placode formation
0.80	GO:0003256	regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
0.79	GO:0060465	pharynx development
0.79	GO:0036302	atrioventricular canal development
0.78	GO:0090398	cellular senescence
0.78	GO:0060045	positive regulation of cardiac muscle cell proliferation
0.77	GO:0003148	outflow tract septum morphogenesis

0.75	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.71	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding

0.66	GO:0005667	transcription factor complex
0.61	GO:0005634	nucleus

sp|Q13214|SEM3B_HUMAN
Semaphorin-3B
Search

SEMA3B

0.94	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B

0.84	GO:0050919	negative chemotaxis
0.51	GO:0007399	nervous system development
0.50	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.50	GO:0000904	cell morphogenesis involved in differentiation
0.49	GO:0120036	plasma membrane bounded cell projection organization
0.47	GO:0060429	epithelium development
0.47	GO:0001763	morphogenesis of a branching structure
0.46	GO:0006928	movement of cell or subcellular component
0.45	GO:0048729	tissue morphogenesis
0.45	GO:0035295	tube development

0.85	GO:0038191	neuropilin binding
0.45	GO:0030215	semaphorin receptor binding
0.42	GO:0045499	chemorepellent activity

0.71	GO:0005615	extracellular space
0.48	GO:1903561	extracellular vesicle
0.41	GO:0005783	endoplasmic reticulum
0.40	GO:0030424	axon
0.30	GO:0016020	membrane

sp|Q13216|ERCC8_HUMAN
DNA excision repair protein ERCC-8
Search

ERCC8

0.91	Excision repair cross-complementing rodent repair deficiency, complementation group 8

0.85	GO:0051865	protein autoubiquitination
0.84	GO:0010165	response to X-ray
0.82	GO:0000209	protein polyubiquitination
0.81	GO:0009411	response to UV
0.79	GO:0006283	transcription-coupled nucleotide-excision repair
0.77	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.71	GO:0006979	response to oxidative stress
0.53	GO:0045739	positive regulation of DNA repair
0.51	GO:0010996	response to auditory stimulus
0.46	GO:0014070	response to organic cyclic compound

0.75	GO:0032403	protein complex binding
0.73	GO:0004842	ubiquitin-protein transferase activity
0.42	GO:0003678	DNA helicase activity
0.42	GO:0008094	DNA-dependent ATPase activity

0.85	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex
0.84	GO:0000109	nucleotide-excision repair complex
0.84	GO:0016363	nuclear matrix
0.50	GO:0043204	perikaryon
0.38	GO:0005654	nucleoplasm
0.37	GO:0005737	cytoplasm

0.73

GO:0004842

sp|Q13217|DNJC3_HUMAN
DnaJ homolog subfamily C member 3
Search

DNAJC3

0.92	Interferon-induced, double-stranded RNA-activated protein kinase inhibitor (Fragment)

0.86	GO:0036494	positive regulation of translation initiation in response to endoplasmic reticulum stress
0.86	GO:1903912	negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
0.78	GO:0070417	cellular response to cold
0.76	GO:0006469	negative regulation of protein kinase activity
0.72	GO:0043066	negative regulation of apoptotic process
0.67	GO:0051603	proteolysis involved in cellular protein catabolic process
0.50	GO:0006986	response to unfolded protein
0.43	GO:0035967	cellular response to topologically incorrect protein
0.40	GO:0043312	neutrophil degranulation
0.40	GO:0016310	phosphorylation

0.81	GO:0051787	misfolded protein binding
0.78	GO:0004860	protein kinase inhibitor activity
0.74	GO:0019901	protein kinase binding
0.71	GO:0051087	chaperone binding
0.41	GO:0016301	kinase activity

0.80	GO:0031205	endoplasmic reticulum Sec complex
0.77	GO:0005788	endoplasmic reticulum lumen
0.65	GO:0005829	cytosol
0.52	GO:0005790	smooth endoplasmic reticulum
0.42	GO:0070062	extracellular exosome
0.41	GO:0035578	azurophil granule lumen
0.30	GO:0016021	integral component of membrane

sp|Q13219|PAPP1_HUMAN
Pappalysin-1
Search

PAPPA

0.82	Pregnancy-associated plasma protein A

0.61	GO:0006508	proteolysis
0.40	GO:0032501	multicellular organismal process
0.39	GO:0032354	response to follicle-stimulating hormone
0.38	GO:0051384	response to glucocorticoid
0.37	GO:0048856	anatomical structure development
0.37	GO:0044703	multi-organism reproductive process
0.35	GO:0007610	behavior
0.33	GO:0044267	cellular protein metabolic process

0.69	GO:0004222	metalloendopeptidase activity
0.37	GO:0008270	zinc ion binding

0.51	GO:0005615	extracellular space
0.30	GO:0044425	membrane part

0.69

GO:0004222

sp|Q13224|NMDE2_HUMAN
Glutamate receptor ionotropic, NMDA 2B
Search

GRIN2B

0.94	Glutamate ionotropic receptor NMDA type subunit 2B

0.79	GO:0060079	excitatory postsynaptic potential
0.77	GO:0035235	ionotropic glutamate receptor signaling pathway
0.59	GO:0034220	ion transmembrane transport
0.59	GO:0045471	response to ethanol
0.59	GO:0060402	calcium ion transport into cytosol
0.59	GO:0019722	calcium-mediated signaling
0.42	GO:0051290	protein heterotetramerization
0.42	GO:0007611	learning or memory
0.41	GO:1900273	positive regulation of long-term synaptic potentiation
0.41	GO:1902951	negative regulation of dendritic spine maintenance

0.81	GO:0005234	extracellularly glutamate-gated ion channel activity
0.77	GO:0004970	ionotropic glutamate receptor activity
0.60	GO:0016594	glycine binding
0.59	GO:0099604	ligand-gated calcium channel activity
0.55	GO:0022843	voltage-gated cation channel activity
0.42	GO:0016595	glutamate binding
0.38	GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential
0.37	GO:0031749	D2 dopamine receptor binding
0.37	GO:0008270	zinc ion binding
0.37	GO:0099583	neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration

0.77	GO:0098794	postsynapse
0.74	GO:0097060	synaptic membrane
0.70	GO:0030054	cell junction
0.63	GO:0017146	NMDA selective glutamate receptor complex
0.42	GO:0032279	asymmetric synapse
0.41	GO:0097458	neuron part
0.40	GO:0070382	exocytic vesicle
0.40	GO:0120025	plasma membrane bounded cell projection
0.40	GO:0009986	cell surface
0.36	GO:0043083	synaptic cleft

sp|Q13227|GPS2_HUMAN
G protein pathway suppressor 2
Search

GPS2

0.97	G protein pathway suppressor 2

0.85	GO:0046329	negative regulation of JNK cascade
0.79	GO:0045599	negative regulation of fat cell differentiation
0.78	GO:0000122	negative regulation of transcription by RNA polymerase II
0.42	GO:0034260	negative regulation of GTPase activity
0.42	GO:0007254	JNK cascade
0.42	GO:0000188	inactivation of MAPK activity

0.82	GO:0030332	cyclin binding
0.81	GO:0003714	transcription corepressor activity
0.43	GO:0005095	GTPase inhibitor activity
0.33	GO:0005509	calcium ion binding
0.33	GO:0004674	protein serine/threonine kinase activity

0.81	GO:0017053	transcriptional repressor complex
0.57	GO:0005634	nucleus
0.38	GO:0070013	intracellular organelle lumen
0.36	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.33

GO:0004674

sp|Q13228|SBP1_HUMAN
Selenium-binding protein 1
Search

SELENBP1

0.78	Selenium-binding protein 1

0.40	GO:0015031	protein transport
0.39	GO:0050873	brown fat cell differentiation
0.33	GO:0007165	signal transduction

0.85	GO:0008430	selenium binding
0.34	GO:0005515	protein binding

0.52	GO:0001650	fibrillar center
0.41	GO:0005829	cytosol
0.38	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

sp|Q13231|CHIT1_HUMAN
Chitotriosidase-1
Search

CHIT1

0.46	Myeloid cell lineage chitinase

0.73	GO:0006030	chitin metabolic process
0.60	GO:0005975	carbohydrate metabolic process
0.58	GO:1901072	glucosamine-containing compound catabolic process
0.54	GO:0006026	aminoglycan catabolic process
0.52	GO:0042737	drug catabolic process
0.47	GO:0090197	positive regulation of chemokine secretion
0.47	GO:0002532	production of molecular mediator involved in inflammatory response
0.39	GO:0044245	polysaccharide digestion
0.37	GO:0002376	immune system process
0.37	GO:0006915	apoptotic process

0.77	GO:0008061	chitin binding
0.66	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.43	GO:0019900	kinase binding
0.33	GO:0061783	peptidoglycan muralytic activity
0.33	GO:0030246	carbohydrate binding

0.63	GO:0005576	extracellular region
0.37	GO:0005764	lysosome
0.37	GO:1904724	tertiary granule lumen
0.37	GO:0035580	specific granule lumen
0.33	GO:0005783	endoplasmic reticulum
0.30	GO:0016020	membrane

0.66

EC:3.2.1

GO:0004553

sp|Q13232|NDK3_HUMAN
Nucleoside diphosphate kinase 3
Search

NME3

0.46	Nucleoside diphosphate kinase

0.78	GO:0006228	UTP biosynthetic process
0.78	GO:0006183	GTP biosynthetic process
0.74	GO:0046036	CTP metabolic process
0.70	GO:0006165	nucleoside diphosphate phosphorylation
0.43	GO:0042981	regulation of apoptotic process
0.41	GO:0006171	cAMP biosynthetic process
0.37	GO:0006869	lipid transport
0.37	GO:0015949	nucleobase-containing small molecule interconversion
0.35	GO:0007427	epithelial cell migration, open tracheal system
0.35	GO:0016334	establishment or maintenance of polarity of follicular epithelium

0.78	GO:0004550	nucleoside diphosphate kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:1901612	cardiolipin binding
0.35	GO:0005515	protein binding
0.35	GO:0046872	metal ion binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding

0.44	GO:0005739	mitochondrion
0.38	GO:0070062	extracellular exosome
0.38	GO:0031970	organelle envelope lumen
0.35	GO:0005880	nuclear microtubule
0.34	GO:0005829	cytosol
0.33	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

0.78

EC:2.7.4.6

GO:0004550

sp|Q13233|M3K1_HUMAN
Mitogen-activated protein kinase kinase kinase 1
Search

MAP3K1

0.95	Mitogen-activated protein kinase kinase kinase 1

0.62	GO:0006468	protein phosphorylation
0.59	GO:0071260	cellular response to mechanical stimulus
0.47	GO:0031098	stress-activated protein kinase signaling cascade
0.46	GO:0032147	activation of protein kinase activity
0.45	GO:0007346	regulation of mitotic cell cycle
0.44	GO:0042981	regulation of apoptotic process
0.39	GO:0043406	positive regulation of MAP kinase activity
0.37	GO:0061029	eyelid development in camera-type eye
0.37	GO:0038095	Fc-epsilon receptor signaling pathway
0.37	GO:0080134	regulation of response to stress

0.62	GO:0004672	protein kinase activity
0.61	GO:0008270	zinc ion binding
0.55	GO:0019901	protein kinase binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0005057	signal transducer activity, downstream of receptor
0.35	GO:0046625	sphingolipid binding
0.35	GO:0008092	cytoskeletal protein binding

0.37	GO:0031941	filamentous actin
0.36	GO:0005737	cytoplasm
0.34	GO:0030054	cell junction
0.30	GO:0016020	membrane

0.34

GO:0004842

sp|Q13237|KGP2_HUMAN
cGMP-dependent protein kinase 2
Search

PRKG2

0.87	cGMP-dependent protein kinase

0.63	GO:0006468	protein phosphorylation
0.43	GO:2001226	negative regulation of chloride transport
0.40	GO:0072659	protein localization to plasma membrane
0.40	GO:0018209	peptidyl-serine modification
0.39	GO:0045794	negative regulation of cell volume
0.38	GO:0071476	cellular hypotonic response
0.38	GO:0032922	circadian regulation of gene expression
0.38	GO:0007526	larval somatic muscle development
0.35	GO:0007264	small GTPase mediated signal transduction
0.34	GO:0065009	regulation of molecular function

0.85	GO:0004692	cGMP-dependent protein kinase activity
0.80	GO:0030553	cGMP binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0042803	protein homodimerization activity
0.35	GO:0005085	guanyl-nucleotide exchange factor activity

0.40	GO:0031965	nuclear membrane
0.39	GO:0016324	apical plasma membrane
0.34	GO:0005829	cytosol

0.85

EC:2.7.11.12

GO:0004692

sp|Q13239|SLAP1_HUMAN
Src-like-adapter
Search

SLA

0.97	Src like adaptor

0.75	GO:0009967	positive regulation of signal transduction
0.49	GO:0038083	peptidyl-tyrosine autophosphorylation
0.47	GO:0045087	innate immune response
0.46	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.46	GO:0016477	cell migration
0.46	GO:0042127	regulation of cell proliferation
0.44	GO:0030154	cell differentiation
0.35	GO:0050849	negative regulation of calcium-mediated signaling
0.34	GO:0042110	T cell activation
0.34	GO:0000122	negative regulation of transcription by RNA polymerase II

0.85	GO:0005070	SH3/SH2 adaptor activity
0.49	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.44	GO:0005102	receptor binding
0.35	GO:0047485	protein N-terminus binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.47	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.38	GO:0005768	endosome
0.34	GO:0005794	Golgi apparatus
0.33	GO:0005654	nucleoplasm
0.33	GO:0044433	cytoplasmic vesicle part
0.33	GO:0098805	whole membrane
0.33	GO:0098588	bounding membrane of organelle

0.49

GO:0004715

sp|Q13241|KLRD1_HUMAN
Natural killer cells antigen CD94
Search

KLRD1

0.96	Killer cell lectin like receptor D1

0.52	GO:0002228	natural killer cell mediated immunity
0.35	GO:0050776	regulation of immune response
0.35	GO:0007166	cell surface receptor signaling pathway

0.67	GO:0030246	carbohydrate binding
0.55	GO:0023024	MHC class I protein complex binding
0.55	GO:0023025	MHC class Ib protein complex binding
0.54	GO:0023029	MHC class Ib protein binding
0.54	GO:1990405	protein antigen binding
0.35	GO:0099600	transmembrane receptor activity
0.34	GO:0038023	signaling receptor activity

0.48	GO:0043235	receptor complex
0.48	GO:0009897	external side of plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q13242|SRSF9_HUMAN
Serine/arginine-rich splicing factor 9
Search

SRSF9

0.89	Serine and arginine rich splicing factor 9

0.54	GO:0048025	negative regulation of mRNA splicing, via spliceosome
0.48	GO:0000395	mRNA 5'-splice site recognition
0.48	GO:0000380	alternative mRNA splicing, via spliceosome
0.47	GO:0060048	cardiac muscle contraction
0.45	GO:0001701	in utero embryonic development
0.39	GO:0043279	response to alkaloid
0.38	GO:0051028	mRNA transport
0.37	GO:0097421	liver regeneration
0.37	GO:0033120	positive regulation of RNA splicing
0.37	GO:0048709	oligodendrocyte differentiation

0.59	GO:0003723	RNA binding
0.53	GO:0019904	protein domain specific binding
0.49	GO:0044547	DNA topoisomerase binding
0.37	GO:0043422	protein kinase B binding

0.51	GO:0005654	nucleoplasm
0.48	GO:0005730	nucleolus
0.47	GO:0035145	exon-exon junction complex
0.46	GO:0071013	catalytic step 2 spliceosome
0.35	GO:0070062	extracellular exosome
0.34	GO:0005737	cytoplasm

sp|Q13243|SRSF5_HUMAN
Serine/arginine-rich splicing factor 5
Search

SRSF5

0.97	Serine and arginine rich splicing factor 5

0.41	GO:0097421	liver regeneration
0.40	GO:0033120	positive regulation of RNA splicing
0.40	GO:0032869	cellular response to insulin stimulus
0.38	GO:0051726	regulation of cell cycle
0.37	GO:0008380	RNA splicing
0.36	GO:0009611	response to wounding
0.36	GO:0006397	mRNA processing
0.35	GO:0006369	termination of RNA polymerase II transcription
0.35	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.34	GO:0031123	RNA 3'-end processing

0.59	GO:0003723	RNA binding
0.41	GO:0043422	protein kinase B binding
0.38	GO:0050733	RS domain binding

0.52	GO:0005730	nucleolus
0.49	GO:0005829	cytosol
0.38	GO:0016607	nuclear speck
0.34	GO:0005882	intermediate filament

sp|Q13247|SRSF6_HUMAN
Serine/arginine-rich splicing factor 6
Search

SRSF6

0.96	Serine and arginine rich splicing factor 6

0.60	GO:0048025	negative regulation of mRNA splicing, via spliceosome
0.60	GO:0045617	negative regulation of keratinocyte differentiation
0.59	GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis
0.58	GO:0010837	regulation of keratinocyte proliferation
0.58	GO:0000380	alternative mRNA splicing, via spliceosome
0.56	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.56	GO:0061041	regulation of wound healing
0.55	GO:0006376	mRNA splice site selection
0.52	GO:0060548	negative regulation of cell death
0.40	GO:2000674	regulation of type B pancreatic cell apoptotic process

0.59	GO:0003723	RNA binding
0.36	GO:0005515	protein binding
0.35	GO:0031491	nucleosome binding
0.34	GO:0008270	zinc ion binding
0.33	GO:0003700	DNA binding transcription factor activity

0.55	GO:0016607	nuclear speck
0.34	GO:0000793	condensed chromosome
0.34	GO:0000785	chromatin
0.32	GO:0005886	plasma membrane

sp|Q13253|NOGG_HUMAN
Noggin
Search

NOG

0.96

Noggin

0.85	GO:0030514	negative regulation of BMP signaling pathway
0.79	GO:0045596	negative regulation of cell differentiation
0.74	GO:0051216	cartilage development
0.65	GO:0030154	cell differentiation
0.63	GO:0060825	fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation
0.63	GO:2000313	regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation
0.62	GO:0060302	negative regulation of cytokine activity
0.62	GO:0090193	positive regulation of glomerulus development
0.61	GO:0060044	negative regulation of cardiac muscle cell proliferation
0.61	GO:0060513	prostatic bud formation

0.57	GO:0019955	cytokine binding
0.53	GO:0042803	protein homodimerization activity
0.34	GO:0032403	protein complex binding

0.60	GO:0005576	extracellular region
0.34	GO:0030424	axon
0.34	GO:0045202	synapse
0.33	GO:0005794	Golgi apparatus
0.33	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q13255|GRM1_HUMAN
Metabotropic glutamate receptor 1
Search

GRM1

0.81	Bifunctional metabotropic receptor for extracellular calcium and glutamate

0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.62	GO:0099566	regulation of postsynaptic cytosolic calcium ion concentration
0.61	GO:0071257	cellular response to electrical stimulus
0.61	GO:0051930	regulation of sensory perception of pain
0.59	GO:0019233	sensory perception of pain
0.58	GO:0000187	activation of MAPK activity
0.57	GO:0000186	activation of MAPKK activity
0.57	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.56	GO:0007626	locomotory behavior
0.55	GO:0007215	glutamate receptor signaling pathway

0.71	GO:0004930	G-protein coupled receptor activity
0.63	GO:0099583	neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration
0.55	GO:0008066	glutamate receptor activity
0.39	GO:0042802	identical protein binding
0.37	GO:0030331	estrogen receptor binding

0.63	GO:0038038	G-protein coupled receptor homodimeric complex
0.58	GO:0014069	postsynaptic density
0.56	GO:0030425	dendrite
0.51	GO:0042734	presynaptic membrane
0.46	GO:0005634	nucleus
0.39	GO:0044309	neuron spine
0.38	GO:0045211	postsynaptic membrane
0.36	GO:0043025	neuronal cell body
0.36	GO:0030424	axon
0.33	GO:0044422	organelle part

sp|Q13257|MD2L1_HUMAN
Mitotic spindle assembly checkpoint protein MAD2A
Search

MAD2L1

0.95	Mitotic arrest deficient 2 like 1

0.82	GO:0007094	mitotic spindle assembly checkpoint
0.53	GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint
0.53	GO:1904667	negative regulation of ubiquitin protein ligase activity
0.51	GO:0042177	negative regulation of protein catabolic process
0.49	GO:0043066	negative regulation of apoptotic process
0.44	GO:0000070	mitotic sister chromatid segregation
0.36	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.36	GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0031145	anaphase-promoting complex-dependent catabolic process
0.35	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process

0.48	GO:0042803	protein homodimerization activity
0.34	GO:0004756	selenide, water dikinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.50	GO:0072686	mitotic spindle
0.49	GO:0048471	perinuclear region of cytoplasm
0.49	GO:0000776	kinetochore
0.49	GO:0005643	nuclear pore
0.46	GO:0005654	nucleoplasm
0.45	GO:0005829	cytosol
0.44	GO:0000922	spindle pole
0.37	GO:0000779	condensed chromosome, centromeric region
0.34	GO:0045120	pronucleus
0.34	GO:0051233	spindle midzone

0.34	EC:2.7.9.3	GO:0004756
0.34	KEGG:R03595	GO:0004756

sp|Q13258|PD2R_HUMAN
Prostaglandin D2 receptor
Search

0.95	prostacyclin receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.61	GO:0071379	cellular response to prostaglandin stimulus
0.60	GO:0034695	response to prostaglandin E
0.58	GO:1901655	cellular response to ketone
0.57	GO:0097306	cellular response to alcohol
0.50	GO:0097755	positive regulation of blood vessel diameter
0.49	GO:0071798	response to prostaglandin D
0.48	GO:0032570	response to progesterone
0.47	GO:0019933	cAMP-mediated signaling
0.47	GO:0030431	sleep

0.85	GO:0004954	prostanoid receptor activity
0.34	GO:0005515	protein binding
0.31	GO:0046872	metal ion binding

0.44	GO:0005886	plasma membrane
0.35	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|Q13261|I15RA_HUMAN
Interleukin-15 receptor subunit alpha
Search

IL15RA

0.97	Interleukin-15 receptor subunit alpha

0.64	GO:0032825	positive regulation of natural killer cell differentiation
0.49	GO:0035723	interleukin-15-mediated signaling pathway
0.45	GO:0008283	cell proliferation
0.45	GO:0007259	JAK-STAT cascade
0.45	GO:0010977	negative regulation of neuron projection development
0.43	GO:0031667	response to nutrient levels

0.46	GO:0004896	cytokine receptor activity
0.40	GO:0005515	protein binding

0.57	GO:0031410	cytoplasmic vesicle
0.48	GO:0031965	nuclear membrane
0.46	GO:0005886	plasma membrane
0.46	GO:0005615	extracellular space
0.44	GO:0012506	vesicle membrane
0.44	GO:0000139	Golgi membrane
0.43	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0016021	integral component of membrane

sp|Q13263|TIF1B_HUMAN
Transcription intermediary factor 1-beta
Search

TRIM28

0.96	Tripartite motif containing 28

0.73	GO:1901536	negative regulation of DNA demethylation
0.73	GO:0045869	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate
0.73	GO:0090309	positive regulation of methylation-dependent chromatin silencing
0.72	GO:0043045	DNA methylation involved in embryo development
0.72	GO:2000653	regulation of genetic imprinting
0.71	GO:1902187	negative regulation of viral release from host cell
0.70	GO:0060028	convergent extension involved in axis elongation
0.70	GO:0042993	positive regulation of transcription factor import into nucleus
0.69	GO:1903507	negative regulation of nucleic acid-templated transcription
0.69	GO:0060669	embryonic placenta morphogenesis

0.78	GO:0003714	transcription corepressor activity
0.76	GO:0035851	Krueppel-associated box domain binding
0.73	GO:0070087	chromo shadow domain binding
0.70	GO:1990841	promoter-specific chromatin binding
0.68	GO:0001105	RNA polymerase II transcription coactivator activity
0.64	GO:0031625	ubiquitin protein ligase binding
0.63	GO:0008270	zinc ion binding
0.60	GO:0004842	ubiquitin-protein transferase activity
0.53	GO:0043565	sequence-specific DNA binding
0.53	GO:0004672	protein kinase activity

0.67	GO:0005719	nuclear euchromatin
0.66	GO:0005720	nuclear heterochromatin
0.61	GO:0090575	RNA polymerase II transcription factor complex
0.58	GO:0005654	nucleoplasm

0.60

GO:0004842

sp|Q13268|DHRS2_HUMAN
Dehydrogenase/reductase SDR family member 2, mitochondrial
Search

0.79	Dehydrogenase/reductase member 2

0.53	GO:0055114	oxidation-reduction process
0.48	GO:0042574	retinal metabolic process
0.46	GO:0043011	myeloid dendritic cell differentiation
0.43	GO:0008202	steroid metabolic process
0.43	GO:0043066	negative regulation of apoptotic process
0.42	GO:0034599	cellular response to oxidative stress
0.42	GO:0051262	protein tetramerization
0.40	GO:0009636	response to toxic substance
0.40	GO:0006066	alcohol metabolic process
0.40	GO:0042180	cellular ketone metabolic process

0.55	GO:0004090	carbonyl reductase (NADPH) activity
0.49	GO:0001758	retinal dehydrogenase activity
0.46	GO:0000253	3-keto sterol reductase activity
0.46	GO:0018455	alcohol dehydrogenase [NAD(P)+] activity
0.40	GO:0005515	protein binding
0.39	GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
0.38	GO:0052650	NADP-retinol dehydrogenase activity

0.49	GO:0042579	microbody
0.46	GO:0005739	mitochondrion
0.43	GO:0005634	nucleus
0.42	GO:0070062	extracellular exosome
0.41	GO:0012505	endomembrane system
0.40	GO:0098805	whole membrane
0.40	GO:0044446	intracellular organelle part
0.40	GO:0098588	bounding membrane of organelle
0.38	GO:0031975	envelope
0.36	GO:0031974	membrane-enclosed lumen

0.55	EC:1.1.1.184	GO:0004090
0.38	KEGG:R08379	GO:0052650

sp|Q13275|SEM3F_HUMAN
Semaphorin-3F
Search

SEMA3F

0.97	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fb

0.83	GO:0050919	negative chemotaxis
0.83	GO:0036486	ventral trunk neural crest cell migration
0.83	GO:0097491	sympathetic neuron projection guidance
0.83	GO:0097490	sympathetic neuron projection extension
0.83	GO:1902287	semaphorin-plexin signaling pathway involved in axon guidance
0.83	GO:0021637	trigeminal nerve structural organization
0.82	GO:1901166	neural crest cell migration involved in autonomic nervous system development
0.82	GO:0021785	branchiomotor neuron axon guidance
0.82	GO:0021612	facial nerve structural organization
0.81	GO:0048843	negative regulation of axon extension involved in axon guidance

0.82	GO:0045499	chemorepellent activity
0.68	GO:0038191	neuropilin binding
0.34	GO:0003723	RNA binding
0.33	GO:0004871	signal transducer activity

0.70

GO:0005615

extracellular space

sp|Q13277|STX3_HUMAN
Syntaxin-3
Search

STX3

0.97	Syntaxin-3 isoform B

0.86	GO:0016081	synaptic vesicle docking
0.66	GO:0006886	intracellular protein transport
0.65	GO:0061025	membrane fusion
0.55	GO:1903540	establishment of protein localization to postsynaptic membrane
0.55	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels
0.55	GO:2000010	positive regulation of protein localization to cell surface
0.54	GO:0097120	receptor localization to synapse
0.53	GO:1903078	positive regulation of protein localization to plasma membrane
0.53	GO:0060291	long-term synaptic potentiation
0.53	GO:0048284	organelle fusion

0.77	GO:0005484	SNAP receptor activity
0.46	GO:0000149	SNARE binding
0.41	GO:0050544	arachidonic acid binding
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.33	GO:0008168	methyltransferase activity
0.33	GO:0008270	zinc ion binding
0.32	GO:0003677	DNA binding
0.32	GO:0032553	ribonucleotide binding

0.79	GO:0098793	presynapse
0.55	GO:0097470	ribbon synapse
0.55	GO:0042589	zymogen granule membrane
0.54	GO:0031201	SNARE complex
0.54	GO:0005766	primary lysosome
0.54	GO:0042581	specific granule
0.54	GO:0070382	exocytic vesicle
0.53	GO:0042470	melanosome
0.52	GO:0044306	neuron projection terminus
0.52	GO:0030027	lamellipodium

0.33

GO:0008168

sp|Q13278|RIG_HUMAN
Putative protein RIG
Search

0.56	Putative protein RIG

sp|Q13283|G3BP1_HUMAN
Ras GTPase-activating protein-binding protein 1
Search

G3BP1

0.92	Ras GTPase-activating protein-binding protein 1

0.50	GO:0034063	stress granule assembly
0.45	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.39	GO:0007264	small GTPase mediated signal transduction
0.38	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.37	GO:0051028	mRNA transport
0.36	GO:0007253	cytoplasmic sequestering of NF-kappaB
0.35	GO:0032392	DNA geometric change

0.59	GO:0003723	RNA binding
0.39	GO:0004386	helicase activity
0.39	GO:0004519	endonuclease activity
0.37	GO:0005515	protein binding
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0003677	DNA binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0008186	RNA-dependent ATPase activity
0.35	GO:0008094	DNA-dependent ATPase activity

0.44	GO:0005829	cytosol
0.44	GO:0010494	cytoplasmic stress granule
0.38	GO:0005634	nucleus
0.37	GO:0005925	focal adhesion
0.36	GO:0005886	plasma membrane

sp|Q13285|STF1_HUMAN
Steroidogenic factor 1
Search

NR5A1

0.92	Steroidogenic factor 1 nuclear receptor

0.78	GO:0043401	steroid hormone mediated signaling pathway
0.60	GO:2000195	negative regulation of female gonad development
0.59	GO:2000020	positive regulation of male gonad development
0.59	GO:0030325	adrenal gland development
0.59	GO:0001553	luteinization
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:0051457	maintenance of protein location in nucleus
0.57	GO:0045944	positive regulation of transcription by RNA polymerase II
0.57	GO:0008584	male gonad development
0.57	GO:0009888	tissue development

0.80	GO:0003707	steroid hormone receptor activity
0.64	GO:0043565	sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.61	GO:0035326	enhancer binding
0.61	GO:0003700	DNA binding transcription factor activity
0.58	GO:0003682	chromatin binding
0.57	GO:0001012	RNA polymerase II regulatory region DNA binding
0.56	GO:0005543	phospholipid binding
0.54	GO:0003690	double-stranded DNA binding
0.49	GO:0019899	enzyme binding

0.61	GO:0005634	nucleus
0.56	GO:0005667	transcription factor complex
0.46	GO:0044446	intracellular organelle part
0.36	GO:0005737	cytoplasm
0.35	GO:0043233	organelle lumen
0.33	GO:0005694	chromosome
0.33	GO:1905369	endopeptidase complex

sp|Q13286|CLN3_HUMAN
Battenin
Search

CLN3

0.88

Battenin

0.60	GO:0007040	lysosome organization
0.57	GO:0097352	autophagosome maturation
0.57	GO:0043524	negative regulation of neuron apoptotic process
0.56	GO:0050885	neuromuscular process controlling balance
0.56	GO:0008306	associative learning
0.56	GO:0051489	regulation of filopodium assembly
0.56	GO:0001508	action potential
0.54	GO:0072659	protein localization to plasma membrane
0.54	GO:0051480	regulation of cytosolic calcium ion concentration
0.52	GO:0035235	ionotropic glutamate receptor signaling pathway

0.56	GO:0048306	calcium-dependent protein binding
0.34	GO:0051082	unfolded protein binding

0.81	GO:0005765	lysosomal membrane
0.55	GO:0005769	early endosome
0.55	GO:0005776	autophagosome
0.54	GO:0005770	late endosome
0.43	GO:0005901	caveola
0.43	GO:0008021	synaptic vesicle
0.42	GO:0005802	trans-Golgi network
0.42	GO:0030176	integral component of endoplasmic reticulum membrane
0.42	GO:0043005	neuron projection
0.41	GO:0005795	Golgi stack

sp|Q13287|NMI_HUMAN
N-myc-interactor
Search

NMI

0.78	N-myc and STAT interactor

0.86	GO:0060333	interferon-gamma-mediated signaling pathway
0.75	GO:0006366	transcription by RNA polymerase II
0.66	GO:0045355	negative regulation of interferon-alpha biosynthetic process
0.66	GO:0045358	negative regulation of interferon-beta biosynthetic process
0.65	GO:1902524	positive regulation of protein K48-linked ubiquitination
0.56	GO:2001141	regulation of RNA biosynthetic process
0.53	GO:0045824	negative regulation of innate immune response
0.30	GO:0035556	intracellular signal transduction
0.30	GO:0006954	inflammatory response

0.75	GO:0003712	transcription cofactor activity
0.54	GO:0042802	identical protein binding
0.40	GO:0003676	nucleic acid binding

0.52	GO:0005654	nucleoplasm
0.51	GO:0005829	cytosol

sp|Q13291|SLAF1_HUMAN
Signaling lymphocytic activation molecule
Search

SLAMF1

0.97	Signaling lymphocyte activation molecule SLAM

0.81	GO:0046649	lymphocyte activation
0.60	GO:0002232	leukocyte chemotaxis involved in inflammatory response
0.60	GO:1902714	negative regulation of interferon-gamma secretion
0.60	GO:0035744	T-helper 1 cell cytokine production
0.60	GO:1902715	positive regulation of interferon-gamma secretion
0.60	GO:0002725	negative regulation of T cell cytokine production
0.59	GO:2000510	positive regulation of dendritic cell chemotaxis
0.59	GO:0010759	positive regulation of macrophage chemotaxis
0.58	GO:0042104	positive regulation of activated T cell proliferation
0.57	GO:0032943	mononuclear cell proliferation

0.64	GO:0004872	receptor activity
0.52	GO:0042802	identical protein binding
0.38	GO:0001618	virus receptor activity
0.37	GO:0003823	antigen binding
0.35	GO:0004871	signal transducer activity

0.75	GO:0009986	cell surface
0.56	GO:0045335	phagocytic vesicle
0.52	GO:0098552	side of membrane
0.46	GO:0044459	plasma membrane part
0.38	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

sp|Q13296|SG2A2_HUMAN
Mammaglobin-A
Search

0.97	Mammaglobin-A

0.73

GO:0030521

androgen receptor signaling pathway

0.63	GO:0046982	protein heterodimerization activity
0.38	GO:0016787	hydrolase activity

0.62	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

0.38

GO:0016787

sp|Q13303|KCAB2_HUMAN
Voltage-gated potassium channel subunit beta-2
Search

KCNAB2

0.90	Voltage-gated potassium channel subunit beta-2

0.73	GO:0071805	potassium ion transmembrane transport
0.50	GO:1901379	regulation of potassium ion transmembrane transport
0.49	GO:0002244	hematopoietic progenitor cell differentiation
0.49	GO:0050905	neuromuscular process
0.44	GO:0065009	regulation of molecular function
0.41	GO:0070995	NADPH oxidation
0.39	GO:2000008	regulation of protein localization to cell surface
0.36	GO:0051969	regulation of transmission of nerve impulse
0.36	GO:0098900	regulation of action potential
0.35	GO:0043312	neutrophil degranulation

0.78	GO:0005249	voltage-gated potassium channel activity
0.51	GO:0015459	potassium channel regulator activity
0.40	GO:0004033	aldo-keto reductase (NADP) activity
0.35	GO:0044325	ion channel binding

0.52	GO:0044224	juxtaparanode region of axon
0.49	GO:0043679	axon terminus
0.49	GO:0014069	postsynaptic density
0.49	GO:0005737	cytoplasm
0.47	GO:0008076	voltage-gated potassium channel complex
0.41	GO:1990031	pinceau fiber
0.38	GO:0030054	cell junction
0.38	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.38	GO:0005874	microtubule
0.34	GO:0012506	vesicle membrane

0.40

GO:0004033

sp|Q13304|GPR17_HUMAN
Uracil nucleotide/cysteinyl leukotriene receptor
Search

GPR17

0.97	Uracil nucleotide/cysteinyl leukotriene receptor

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.59	GO:0002862	negative regulation of inflammatory response to antigenic stimulus
0.49	GO:0035025	positive regulation of Rho protein signal transduction
0.47	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.43	GO:0002376	immune system process
0.36	GO:0070098	chemokine-mediated signaling pathway
0.35	GO:0035590	purinergic nucleotide receptor signaling pathway
0.34	GO:0048872	homeostasis of number of cells
0.33	GO:0007596	blood coagulation

0.72	GO:0004930	G-protein coupled receptor activity
0.36	GO:0001653	peptide receptor activity
0.35	GO:0004896	cytokine receptor activity
0.35	GO:0016502	nucleotide receptor activity
0.35	GO:0035586	purinergic receptor activity
0.33	GO:0005515	protein binding

0.42	GO:0005887	integral component of plasma membrane
0.33	GO:0043231	intracellular membrane-bounded organelle

sp|Q13308|PTK7_HUMAN
Inactive tyrosine-protein kinase 7
Search

PTK7

0.96	Inactive tyrosine-protein kinase 7

0.85	GO:0060071	Wnt signaling pathway, planar cell polarity pathway
0.85	GO:0060026	convergent extension
0.84	GO:0001736	establishment of planar polarity
0.63	GO:0006468	protein phosphorylation
0.58	GO:0060484	lung-associated mesenchyme development
0.57	GO:0003401	axis elongation
0.57	GO:0090178	regulation of establishment of planar polarity involved in neural tube closure
0.57	GO:0045198	establishment of epithelial cell apical/basal polarity
0.57	GO:0090103	cochlea morphogenesis
0.56	GO:0060976	coronary vasculature development

0.86	GO:1904929	coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway
0.63	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0005515	protein binding
0.35	GO:0004888	transmembrane signaling receptor activity
0.34	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.34	GO:0000987	proximal promoter sequence-specific DNA binding

0.66	GO:0005887	integral component of plasma membrane
0.51	GO:0005911	cell-cell junction
0.35	GO:0005925	focal adhesion
0.34	GO:0005634	nucleus

sp|Q13309|SKP2_HUMAN
S-phase kinase-associated protein 2
Search

SKP2

0.97	S-phase kinase-associated protein 2

0.67	GO:1902916	positive regulation of protein polyubiquitination
0.67	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway
0.64	GO:0000086	G2/M transition of mitotic cell cycle
0.63	GO:0000082	G1/S transition of mitotic cell cycle
0.62	GO:0000209	protein polyubiquitination
0.57	GO:0042981	regulation of apoptotic process
0.56	GO:0006511	ubiquitin-dependent protein catabolic process
0.56	GO:0051726	regulation of cell cycle
0.53	GO:0016310	phosphorylation
0.47	GO:0071460	cellular response to cell-matrix adhesion

0.58	GO:0061630	ubiquitin protein ligase activity
0.56	GO:0042802	identical protein binding
0.56	GO:0016301	kinase activity

0.62	GO:0019005	SCF ubiquitin ligase complex
0.57	GO:0005730	nucleolus
0.54	GO:0005829	cytosol
0.36	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

sp|Q13310|PABP4_HUMAN
Polyadenylate-binding protein 4
Search

PABPC4

0.62	Polyadenylate-binding protein (Fragment)

0.54	GO:0061013	regulation of mRNA catabolic process
0.54	GO:0061515	myeloid cell development
0.54	GO:0043487	regulation of RNA stability
0.39	GO:1902369	negative regulation of RNA catabolic process
0.38	GO:0045070	positive regulation of viral genome replication
0.37	GO:1903312	negative regulation of mRNA metabolic process
0.36	GO:0010628	positive regulation of gene expression
0.35	GO:0000413	protein peptidyl-prolyl isomerization
0.34	GO:1903313	positive regulation of mRNA metabolic process
0.34	GO:0031047	gene silencing by RNA

0.58	GO:0003723	RNA binding
0.37	GO:0008022	protein C-terminus binding
0.35	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.35	GO:0031370	eukaryotic initiation factor 4G binding
0.34	GO:0043621	protein self-association
0.33	GO:0046983	protein dimerization activity

0.54	GO:0010494	cytoplasmic stress granule
0.48	GO:0005829	cytosol
0.45	GO:0005634	nucleus
0.34	GO:1902494	catalytic complex
0.34	GO:0005844	polysome
0.34	GO:0044446	intracellular organelle part

0.35

GO:0003755

sp|Q13315|ATM_HUMAN
Serine-protein kinase ATM
Search

ATM

0.96	Serine-protein kinase ATM

0.86	GO:0090399	replicative senescence
0.85	GO:0016572	histone phosphorylation
0.82	GO:0010212	response to ionizing radiation
0.80	GO:0000077	DNA damage checkpoint
0.78	GO:0000723	telomere maintenance
0.74	GO:0002331	pre-B cell allelic exclusion
0.73	GO:1904882	regulation of telomerase catalytic core complex assembly
0.73	GO:0097694	establishment of RNA localization to telomere
0.72	GO:0006975	DNA damage induced protein phosphorylation
0.72	GO:0036289	peptidyl-serine autophosphorylation

0.70	GO:0004677	DNA-dependent protein kinase activity
0.68	GO:0047485	protein N-terminus binding
0.68	GO:0016303	1-phosphatidylinositol-3-kinase activity
0.60	GO:0032403	protein complex binding
0.56	GO:0046983	protein dimerization activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0008144	drug binding
0.39	GO:0003735	structural constituent of ribosome

0.63	GO:0000781	chromosome, telomeric region
0.62	GO:0005819	spindle
0.60	GO:1990391	DNA repair complex
0.59	GO:0005730	nucleolus
0.40	GO:0031410	cytoplasmic vesicle
0.38	GO:0005840	ribosome
0.38	GO:0005654	nucleoplasm
0.36	GO:0044454	nuclear chromosome part
0.30	GO:0016020	membrane

0.70	EC:2.7.11	GO:0004677
0.68	KEGG:R03362	GO:0016303

sp|Q13316|DMP1_HUMAN
Dentin matrix acidic phosphoprotein 1
Search

DMP1

0.85	Dentin matrix acidic phosphoprotein 1

0.83	GO:0001503	ossification
0.80	GO:0030198	extracellular matrix organization
0.55	GO:0070173	regulation of enamel mineralization
0.52	GO:0010811	positive regulation of cell-substrate adhesion
0.39	GO:0031214	biomineral tissue development
0.36	GO:0043687	post-translational protein modification
0.35	GO:0007155	cell adhesion

0.52	GO:0050840	extracellular matrix binding
0.36	GO:0005178	integrin binding
0.35	GO:0005509	calcium ion binding

0.37	GO:0005578	proteinaceous extracellular matrix
0.36	GO:0005788	endoplasmic reticulum lumen
0.35	GO:0005634	nucleus

sp|Q13319|CD5R2_HUMAN
Cyclin-dependent kinase 5 activator 2
Search

CDK5R2

0.90	Cyclin-dependent kinase 5 activator

0.80	GO:0071902	positive regulation of protein serine/threonine kinase activity
0.66	GO:0021722	superior olivary nucleus maturation
0.63	GO:0021819	layer formation in cerebral cortex
0.61	GO:0021766	hippocampus development
0.61	GO:0021549	cerebellum development
0.60	GO:0001764	neuron migration
0.57	GO:0051050	positive regulation of transport
0.55	GO:0017158	regulation of calcium ion-dependent exocytosis
0.52	GO:0042501	serine phosphorylation of STAT protein
0.50	GO:0007158	neuron cell-cell adhesion

0.86	GO:0016534	cyclin-dependent protein kinase 5 activator activity
0.50	GO:0035255	ionotropic glutamate receptor binding
0.49	GO:0016301	kinase activity
0.48	GO:0002020	protease binding
0.46	GO:0019901	protein kinase binding
0.46	GO:0051015	actin filament binding
0.38	GO:0045296	cadherin binding
0.38	GO:0046875	ephrin receptor binding
0.37	GO:0008289	lipid binding
0.36	GO:0005509	calcium ion binding

0.86	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex
0.47	GO:0048471	perinuclear region of cytoplasm
0.44	GO:0005654	nucleoplasm
0.38	GO:0043197	dendritic spine
0.38	GO:0031594	neuromuscular junction
0.38	GO:0030426	growth cone
0.38	GO:0014069	postsynaptic density
0.38	GO:0043025	neuronal cell body
0.38	GO:0043292	contractile fiber
0.38	GO:0030424	axon

0.32

GO:0016773

sp|Q13322|GRB10_HUMAN
Growth factor receptor-bound protein 10
Search

GRB10

0.90	Growth factor receptor-bound protein 10

0.80	GO:0046627	negative regulation of insulin receptor signaling pathway
0.70	GO:0009967	positive regulation of signal transduction
0.60	GO:0007165	signal transduction
0.56	GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway
0.54	GO:0046325	negative regulation of glucose import
0.54	GO:0030178	negative regulation of Wnt signaling pathway
0.49	GO:0042326	negative regulation of phosphorylation
0.36	GO:0045719	negative regulation of glycogen biosynthetic process
0.36	GO:0032869	cellular response to insulin stimulus
0.35	GO:0007411	axon guidance

0.81	GO:0005158	insulin receptor binding
0.79	GO:0005070	SH3/SH2 adaptor activity
0.35	GO:0042802	identical protein binding

0.43	GO:0043234	protein complex
0.34	GO:0005829	cytosol
0.33	GO:0005886	plasma membrane

sp|Q13323|BIK_HUMAN
Bcl-2-interacting killer
Search

BIK

0.97	Bcl-2-interacting killer

0.78	GO:0006915	apoptotic process
0.76	GO:0032464	positive regulation of protein homooligomerization
0.73	GO:0090200	positive regulation of release of cytochrome c from mitochondria
0.53	GO:0008584	male gonad development
0.44	GO:0007283	spermatogenesis
0.43	GO:0007005	mitochondrion organization

0.47	GO:0051400	BH domain binding
0.42	GO:0046982	protein heterodimerization activity

0.44	GO:0012505	endomembrane system
0.44	GO:0044429	mitochondrial part
0.43	GO:0031967	organelle envelope
0.42	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

sp|Q13324|CRFR2_HUMAN
Corticotropin-releasing factor receptor 2
Search

CRHR2

0.92	Corticotropin releasing hormone receptor 2

0.71	GO:0007166	cell surface receptor signaling pathway
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.41	GO:0043435	response to corticotropin-releasing hormone
0.40	GO:0032099	negative regulation of appetite
0.38	GO:0009755	hormone-mediated signaling pathway

0.72	GO:0004930	G-protein coupled receptor activity
0.42	GO:0043404	corticotropin-releasing hormone receptor activity

0.54	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q13325|IFIT5_HUMAN
Interferon-induced protein with tetratricopeptide repeats 5
Search

IFIT5

0.96	Interferon-induced protein with tetratricopeptide repeats 5

0.72	GO:0009615	response to virus
0.66	GO:0045071	negative regulation of viral genome replication
0.66	GO:0006952	defense response
0.65	GO:0002376	immune system process
0.65	GO:0071345	cellular response to cytokine stimulus
0.62	GO:0035455	response to interferon-alpha
0.59	GO:0071360	cellular response to exogenous dsRNA
0.58	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.57	GO:0050688	regulation of defense response to virus
0.55	GO:0032091	negative regulation of protein binding

0.59	GO:0008266	poly(U) RNA binding
0.57	GO:0000339	RNA cap binding
0.52	GO:0003690	double-stranded DNA binding
0.50	GO:0000049	tRNA binding
0.41	GO:0005515	protein binding

0.61	GO:0008385	IkappaB kinase complex
0.59	GO:0032587	ruffle membrane
0.56	GO:0045177	apical part of cell
0.53	GO:0015629	actin cytoskeleton
0.46	GO:0043231	intracellular membrane-bounded organelle
0.42	GO:0044216	other organism cell
0.42	GO:0018995	host
0.40	GO:0012505	endomembrane system

sp|Q13326|SGCG_HUMAN
Gamma-sarcoglycan
Search

SGCG

0.97	Gamma-sarcoglycan

0.51	GO:0060047	heart contraction
0.50	GO:0048738	cardiac muscle tissue development
0.49	GO:0055001	muscle cell development
0.49	GO:0007517	muscle organ development
0.44	GO:0061024	membrane organization
0.38	GO:0048798	swim bladder inflation
0.37	GO:0007525	somatic muscle development
0.37	GO:0007368	determination of left/right symmetry

0.34

GO:0005515

protein binding

0.85	GO:0016012	sarcoglycan complex
0.57	GO:0042383	sarcolemma
0.48	GO:0005654	nucleoplasm
0.38	GO:0005856	cytoskeleton
0.34	GO:0005737	cytoplasm
0.34	GO:0005887	integral component of plasma membrane

sp|Q13330|MTA1_HUMAN
Metastasis-associated protein MTA1
Search

MTA1

0.90	Metastasis associated 1

0.67	GO:1902499	positive regulation of protein autoubiquitination
0.61	GO:0010212	response to ionizing radiation
0.59	GO:0040029	regulation of gene expression, epigenetic
0.58	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.57	GO:0006355	regulation of transcription, DNA-templated
0.57	GO:0006302	double-strand break repair
0.55	GO:1903507	negative regulation of nucleic acid-templated transcription
0.38	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle
0.37	GO:0008284	positive regulation of cell proliferation
0.36	GO:0060215	primitive hemopoiesis

0.77	GO:0003682	chromatin binding
0.65	GO:0043565	sequence-specific DNA binding
0.64	GO:0001103	RNA polymerase II repressing transcription factor binding
0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.61	GO:0001047	core promoter binding
0.60	GO:0003714	transcription corepressor activity
0.59	GO:0003713	transcription coactivator activity
0.37	GO:0032403	protein complex binding

0.61	GO:0005634	nucleus
0.55	GO:0005874	microtubule
0.52	GO:0005829	cytosol
0.52	GO:0012505	endomembrane system
0.52	GO:0031974	membrane-enclosed lumen
0.48	GO:0031967	organelle envelope

sp|Q13332|PTPRS_HUMAN
Receptor-type tyrosine-protein phosphatase S
Search

0.82	Receptor-type tyrosine-protein phosphatase S

0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.49	GO:0021537	telencephalon development
0.48	GO:0034164	negative regulation of toll-like receptor 9 signaling pathway
0.47	GO:0032687	negative regulation of interferon-alpha production
0.47	GO:0048671	negative regulation of collateral sprouting
0.47	GO:0061000	negative regulation of dendritic spine development
0.47	GO:0048681	negative regulation of axon regeneration
0.47	GO:0032688	negative regulation of interferon-beta production
0.46	GO:0090557	establishment of endothelial intestinal barrier
0.46	GO:0030517	negative regulation of axon extension

0.74	GO:0004725	protein tyrosine phosphatase activity
0.47	GO:0035374	chondroitin sulfate binding
0.45	GO:0008201	heparin binding
0.38	GO:0043395	heparan sulfate proteoglycan binding
0.34	GO:0042803	protein homodimerization activity

0.38	GO:0099061	integral component of postsynaptic density membrane
0.38	GO:0030285	integral component of synaptic vesicle membrane
0.37	GO:0043204	perikaryon
0.37	GO:0030424	axon
0.36	GO:0030054	cell junction
0.34	GO:0070062	extracellular exosome

0.74

GO:0004725

sp|Q13336|UT1_HUMAN
Urea transporter 1
Search

SLC14A1

0.71	Urea transporter

0.82	GO:0071918	urea transmembrane transport
0.54	GO:0006833	water transport

0.83	GO:0015204	urea transmembrane transporter activity
0.54	GO:0005372	water transmembrane transporter activity
0.50	GO:0022838	substrate-specific channel activity
0.35	GO:0050839	cell adhesion molecule binding
0.35	GO:0042802	identical protein binding

0.53	GO:0005886	plasma membrane
0.50	GO:0005730	nucleolus
0.30	GO:0016021	integral component of membrane

sp|Q13342|SP140_HUMAN
Nuclear body protein SP140
Search

SP100

0.77	SP100 nuclear antigen

0.71	GO:1902044	regulation of Fas signaling pathway
0.69	GO:0046826	negative regulation of protein export from nucleus
0.68	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
0.68	GO:0034340	response to type I interferon
0.66	GO:1902041	regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.66	GO:0010596	negative regulation of endothelial cell migration
0.66	GO:0043392	negative regulation of DNA binding
0.65	GO:0034341	response to interferon-gamma
0.64	GO:0043433	negative regulation of DNA binding transcription factor activity
0.63	GO:0045765	regulation of angiogenesis

0.69	GO:0070087	chromo shadow domain binding
0.63	GO:0003714	transcription corepressor activity
0.61	GO:0003713	transcription coactivator activity
0.60	GO:0019900	kinase binding
0.59	GO:0042803	protein homodimerization activity
0.55	GO:0003677	DNA binding
0.53	GO:0046872	metal ion binding

0.67	GO:0016604	nuclear body
0.64	GO:0030870	Mre11 complex
0.42	GO:0005737	cytoplasm

sp|Q13347|EIF3I_HUMAN
Eukaryotic translation initiation factor 3 subunit I
Search

EIF3I

0.68	Eukaryotic translation initiation factor 3 subunit I

0.72	GO:0006413	translational initiation
0.68	GO:0002181	cytoplasmic translation
0.68	GO:0006446	regulation of translational initiation
0.64	GO:0022618	ribonucleoprotein complex assembly
0.44	GO:0002040	sprouting angiogenesis
0.44	GO:0001889	liver development
0.35	GO:0035556	intracellular signal transduction

0.73	GO:0003743	translation initiation factor activity
0.35	GO:0005515	protein binding
0.32	GO:0046872	metal ion binding

0.78	GO:0005852	eukaryotic translation initiation factor 3 complex
0.69	GO:0016282	eukaryotic 43S preinitiation complex
0.69	GO:0033290	eukaryotic 48S preinitiation complex
0.36	GO:0070062	extracellular exosome
0.33	GO:0005829	cytosol

sp|Q13349|ITAD_HUMAN
Integrin alpha-D
Search

0.91	Integrin subunit alpha D

0.80	GO:0007229	integrin-mediated signaling pathway
0.72	GO:0007155	cell adhesion
0.61	GO:0043315	positive regulation of neutrophil degranulation
0.59	GO:0010668	ectodermal cell differentiation
0.58	GO:0032930	positive regulation of superoxide anion generation
0.53	GO:0050798	activated T cell proliferation
0.50	GO:2000361	regulation of prostaglandin-E synthase activity
0.49	GO:1903533	regulation of protein targeting
0.49	GO:0045963	negative regulation of dopamine metabolic process
0.49	GO:0090316	positive regulation of intracellular protein transport

0.53	GO:0031072	heat shock protein binding
0.49	GO:0001851	complement component C3b binding
0.45	GO:0043395	heparan sulfate proteoglycan binding
0.44	GO:0008201	heparin binding
0.43	GO:0046982	protein heterodimerization activity
0.38	GO:0046872	metal ion binding
0.35	GO:0004872	receptor activity
0.34	GO:0003735	structural constituent of ribosome

0.81	GO:0008305	integrin complex
0.57	GO:0009986	cell surface
0.55	GO:0044853	plasma membrane raft
0.50	GO:0005615	extracellular space
0.49	GO:0098552	side of membrane
0.44	GO:1903561	extracellular vesicle
0.41	GO:0070821	tertiary granule membrane
0.38	GO:0005634	nucleus
0.38	GO:0101003	ficolin-1-rich granule membrane
0.37	GO:0035579	specific granule membrane

sp|Q13351|KLF1_HUMAN
Krueppel-like factor 1
Search

KLF1

0.90	Kruppel like factor 1

0.76	GO:0030218	erythrocyte differentiation
0.69	GO:0045893	positive regulation of transcription, DNA-templated
0.55	GO:0071499	cellular response to laminar fluid shear stress
0.53	GO:0045429	positive regulation of nitric oxide biosynthetic process
0.47	GO:0051247	positive regulation of protein metabolic process
0.47	GO:0043618	regulation of transcription from RNA polymerase II promoter in response to stress
0.46	GO:1904998	negative regulation of leukocyte adhesion to arterial endothelial cell
0.46	GO:2000342	negative regulation of chemokine (C-X-C motif) ligand 2 production
0.46	GO:0045415	negative regulation of interleukin-8 biosynthetic process
0.46	GO:0046984	regulation of hemoglobin biosynthetic process

0.72	GO:0000987	proximal promoter sequence-specific DNA binding
0.47	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.44	GO:1990841	promoter-specific chromatin binding
0.44	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.43	GO:0001085	RNA polymerase II transcription factor binding
0.42	GO:0001010	transcription factor activity, sequence-specific DNA binding transcription factor recruiting
0.40	GO:0008013	beta-catenin binding
0.40	GO:0001047	core promoter binding

0.71	GO:0000790	nuclear chromatin
0.64	GO:0005654	nucleoplasm
0.41	GO:0000791	euchromatin
0.39	GO:0044798	nuclear transcription factor complex
0.34	GO:0005737	cytoplasm

sp|Q13352|CENPR_HUMAN
Centromere protein R
Search

ITGB3BP

0.97	Centromere protein R

0.86	GO:0034080	CENP-A containing nucleosome assembly
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.45	GO:0006351	transcription, DNA-templated
0.43	GO:0007229	integrin-mediated signaling pathway
0.41	GO:0006915	apoptotic process
0.39	GO:0051301	cell division
0.39	GO:0007049	cell cycle
0.38	GO:0043065	positive regulation of apoptotic process

0.38	GO:0008022	protein C-terminus binding
0.35	GO:0004871	signal transducer activity

0.57	GO:0000777	condensed chromosome kinetochore
0.48	GO:0005634	nucleus
0.45	GO:0043233	organelle lumen
0.36	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|Q13356|PPIL2_HUMAN
Peptidyl-prolyl cis-trans isomerase-like 2
Search

PPIL2

0.91	Peptidylprolyl isomerase like 2

0.70	GO:0000413	protein peptidyl-prolyl isomerization
0.70	GO:0016567	protein ubiquitination
0.67	GO:0006457	protein folding
0.53	GO:0072659	protein localization to plasma membrane
0.35	GO:0050900	leukocyte migration

0.70	GO:0004842	ubiquitin-protein transferase activity
0.70	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.52	GO:0061659	ubiquitin-like protein ligase activity
0.33	GO:0005515	protein binding

0.47	GO:0005654	nucleoplasm
0.41	GO:0005886	plasma membrane
0.38	GO:0005737	cytoplasm
0.34	GO:0012505	endomembrane system
0.30	GO:0044425	membrane part

0.70	EC:5.2.1.8	GO:0003755
0.70	KEGG:R03876	GO:0004842

sp|Q13360|ZN177_HUMAN
Zinc finger protein 177
Search

0.66	LOW QUALITY PROTEIN: zinc finger protein OZF-like

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.36	GO:0006351	transcription, DNA-templated
0.35	GO:0007219	Notch signaling pathway
0.35	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.34	GO:0007010	cytoskeleton organization
0.34	GO:0007186	G-protein coupled receptor signaling pathway
0.34	GO:0022604	regulation of cell morphogenesis
0.34	GO:1902680	positive regulation of RNA biosynthetic process

0.52	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.42	GO:0003700	DNA binding transcription factor activity
0.35	GO:0004984	olfactory receptor activity
0.34	GO:0004930	G-protein coupled receptor activity
0.34	GO:0003682	chromatin binding
0.34	GO:0005515	protein binding

0.44	GO:0005622	intracellular
0.37	GO:0043227	membrane-bounded organelle
0.34	GO:0043233	organelle lumen
0.33	GO:0043228	non-membrane-bounded organelle
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane
0.30	GO:0005576	extracellular region

sp|Q13361|MFAP5_HUMAN
Microfibrillar-associated protein 5
Search

MFAP5

0.57	LOW QUALITY PROTEIN: microfibrillar-associated protein 5

0.59	GO:0060216	definitive hemopoiesis
0.51	GO:0097435	supramolecular fiber organization
0.39	GO:0048048	embryonic eye morphogenesis
0.37	GO:0048050	post-embryonic eye morphogenesis
0.36	GO:0030198	extracellular matrix organization
0.36	GO:0001568	blood vessel development

0.38	GO:0005201	extracellular matrix structural constituent
0.36	GO:0097493	structural molecule activity conferring elasticity
0.36	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
0.35	GO:0005515	protein binding
0.35	GO:0008270	zinc ion binding

0.86	GO:0001527	microfibril
0.53	GO:0005578	proteinaceous extracellular matrix
0.51	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane

0.36

EC:3.5.4

GO:0016814

sp|Q13362|2A5G_HUMAN
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform
Search

PPP2R5C

0.61	Serine/threonine protein phosphatase 2A regulatory subunit

0.79	GO:0043666	regulation of phosphoprotein phosphatase activity
0.60	GO:0007165	signal transduction
0.50	GO:0008285	negative regulation of cell proliferation
0.50	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.39	GO:0071158	positive regulation of cell cycle arrest
0.39	GO:0031571	mitotic G1 DNA damage checkpoint
0.37	GO:0006915	apoptotic process
0.37	GO:0016485	protein processing
0.35	GO:0051898	negative regulation of protein kinase B signaling
0.35	GO:0014066	regulation of phosphatidylinositol 3-kinase signaling

0.80	GO:0019888	protein phosphatase regulator activity
0.35	GO:0005515	protein binding
0.35	GO:0008233	peptidase activity

0.81	GO:0000159	protein phosphatase type 2A complex
0.50	GO:0000775	chromosome, centromeric region
0.47	GO:0005794	Golgi apparatus
0.46	GO:0005654	nucleoplasm
0.46	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.35

GO:0008233

sp|Q13363|CTBP1_HUMAN
C-terminal-binding protein 1
Search

CTBP1

0.96	C-terminal-binding protein 1

0.56	GO:1903756	regulation of transcription from RNA polymerase II promoter by histone modification
0.55	GO:0090241	negative regulation of histone H4 acetylation
0.54	GO:0050872	white fat cell differentiation
0.54	GO:0031065	positive regulation of histone deacetylation
0.53	GO:0055114	oxidation-reduction process
0.50	GO:0000122	negative regulation of transcription by RNA polymerase II
0.47	GO:0051726	regulation of cell cycle
0.35	GO:0099526	presynapse to nucleus signaling pathway
0.34	GO:0008285	negative regulation of cell proliferation
0.34	GO:0006351	transcription, DNA-templated

0.68	GO:0051287	NAD binding
0.66	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
0.53	GO:0001106	RNA polymerase II transcription corepressor activity
0.52	GO:0070491	repressing transcription factor binding
0.49	GO:0019904	protein domain specific binding
0.44	GO:0042803	protein homodimerization activity
0.42	GO:0003700	DNA binding transcription factor activity
0.35	GO:0008022	protein C-terminus binding
0.33	GO:0016746	transferase activity, transferring acyl groups

0.51	GO:0017053	transcriptional repressor complex
0.48	GO:0005667	transcription factor complex
0.46	GO:0005654	nucleoplasm
0.42	GO:0005829	cytosol
0.34	GO:0098793	presynapse

0.66

GO:0016616

sp|Q13367|AP3B2_HUMAN
AP-3 complex subunit beta-2
Search

AP3B2

0.81	AP-3 complex subunit beta

0.69	GO:0006886	intracellular protein transport
0.68	GO:0016192	vesicle-mediated transport
0.57	GO:0008089	anterograde axonal transport
0.56	GO:0047496	vesicle transport along microtubule
0.54	GO:0097480	establishment of synaptic vesicle localization
0.38	GO:0048007	antigen processing and presentation, exogenous lipid antigen via MHC class Ib
0.38	GO:0051138	positive regulation of NK T cell differentiation
0.38	GO:0061462	protein localization to lysosome
0.37	GO:0007041	lysosomal transport
0.37	GO:0072666	establishment of protein localization to vacuole

0.40	GO:0030276	clathrin binding
0.36	GO:0030742	GTP-dependent protein binding
0.36	GO:0019903	protein phosphatase binding
0.34	GO:0048487	beta-tubulin binding
0.33	GO:0005215	transporter activity
0.32	GO:0003723	RNA binding

0.80	GO:0030123	AP-3 adaptor complex
0.56	GO:1904115	axon cytoplasm
0.42	GO:0030131	clathrin adaptor complex
0.38	GO:0030665	clathrin-coated vesicle membrane
0.36	GO:0005794	Golgi apparatus
0.35	GO:0030137	COPI-coated vesicle
0.34	GO:0005765	lysosomal membrane
0.34	GO:0031984	organelle subcompartment

sp|Q13368|MPP3_HUMAN
MAGUK p55 subfamily member 3
Search

MPP3

0.97	Membrane palmitoylated protein 3

0.53	GO:0035335	peptidyl-tyrosine dephosphorylation
0.50	GO:0046710	GDP metabolic process
0.48	GO:0046037	GMP metabolic process
0.42	GO:0007165	signal transduction
0.41	GO:0016310	phosphorylation

0.67	GO:0030165	PDZ domain binding
0.55	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.53	GO:0004725	protein tyrosine phosphatase activity
0.50	GO:0004385	guanylate kinase activity

0.45

GO:0005887

integral component of plasma membrane

0.55

GO:0008138

sp|Q13370|PDE3B_HUMAN
cGMP-inhibited 3',5'-cyclic phosphodiesterase B
Search

PDE3B

0.56	Phosphodiesterase

0.61	GO:0050995	negative regulation of lipid catabolic process
0.60	GO:0007165	signal transduction
0.58	GO:0006198	cAMP catabolic process
0.58	GO:0016525	negative regulation of angiogenesis
0.57	GO:0007162	negative regulation of cell adhesion
0.40	GO:0032869	cellular response to insulin stimulus
0.39	GO:0001525	angiogenesis
0.38	GO:0031018	endocrine pancreas development
0.37	GO:0050796	regulation of insulin secretion
0.37	GO:0042593	glucose homeostasis

0.78	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.53	GO:0046872	metal ion binding
0.41	GO:0043422	protein kinase B binding
0.36	GO:0030552	cAMP binding
0.35	GO:0051219	phosphoprotein binding
0.33	GO:0008144	drug binding

0.59	GO:0032045	guanyl-nucleotide exchange factor complex
0.37	GO:0005794	Golgi apparatus
0.37	GO:0005783	endoplasmic reticulum
0.36	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.78

GO:0004114

sp|Q13371|PHLP_HUMAN
Phosducin-like protein
Search

PDCL

0.93	Phosducin like

0.85	GO:1902605	heterotrimeric G-protein complex assembly
0.72	GO:0007601	visual perception
0.56	GO:0008616	queuosine biosynthetic process
0.46	GO:0061084	negative regulation of protein refolding
0.41	GO:0016567	protein ubiquitination
0.41	GO:0010608	posttranscriptional regulation of gene expression
0.40	GO:0050896	response to stimulus
0.39	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.39	GO:0006457	protein folding
0.39	GO:0048535	lymph node development

0.60	GO:0008479	queuine tRNA-ribosyltransferase activity
0.42	GO:0003729	mRNA binding
0.41	GO:0004842	ubiquitin-protein transferase activity
0.40	GO:0032403	protein complex binding
0.38	GO:0005057	signal transducer activity, downstream of receptor
0.36	GO:0046872	metal ion binding
0.36	GO:0004859	phospholipase inhibitor activity
0.34	GO:0003677	DNA binding

0.48	GO:0005737	cytoplasm
0.43	GO:0001750	photoreceptor outer segment
0.38	GO:0001917	photoreceptor inner segment
0.37	GO:0009986	cell surface
0.35	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0044425	membrane part

0.60	EC:2.4.2.29	GO:0008479
0.41	KEGG:R03876	GO:0004842

sp|Q13387|JIP2_HUMAN
C-Jun-amino-terminal kinase-interacting protein 2
Search

MAPK8IP2

0.83	Mitogen-activated protein kinase 8 interacting protein 2

0.81	GO:0046958	nonassociative learning
0.81	GO:2000310	regulation of NMDA receptor activity
0.81	GO:0007254	JNK cascade
0.80	GO:2000311	regulation of AMPA receptor activity
0.80	GO:0001662	behavioral fear response
0.79	GO:0051966	regulation of synaptic transmission, glutamatergic
0.78	GO:0035176	social behavior
0.78	GO:0046328	regulation of JNK cascade
0.77	GO:0007617	mating behavior
0.77	GO:0048813	dendrite morphogenesis

0.81	GO:0019894	kinesin binding
0.74	GO:0019900	kinase binding
0.50	GO:0035591	signaling adaptor activity
0.49	GO:0032947	protein complex scaffold activity
0.42	GO:0016301	kinase activity

0.76	GO:0044297	cell body
0.75	GO:0014069	postsynaptic density
0.75	GO:0036477	somatodendritic compartment
0.51	GO:0044302	dentate gyrus mossy fiber
0.47	GO:0005737	cytoplasm
0.46	GO:0120038	plasma membrane bounded cell projection part
0.39	GO:0005886	plasma membrane

sp|Q13393|PLD1_HUMAN
Phospholipase D1
Search

PLD1

0.55	Phospholipase

0.81	GO:0006654	phosphatidic acid biosynthetic process
0.80	GO:0048017	inositol lipid-mediated signaling
0.69	GO:0016042	lipid catabolic process
0.66	GO:0032534	regulation of microvillus assembly
0.43	GO:0048870	cell motility
0.38	GO:0050830	defense response to Gram-positive bacterium
0.37	GO:0001525	angiogenesis
0.37	GO:0043312	neutrophil degranulation
0.36	GO:0007265	Ras protein signal transduction
0.36	GO:0043434	response to peptide hormone

0.83	GO:0004630	phospholipase D activity
0.78	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity
0.75	GO:0035091	phosphatidylinositol binding
0.36	GO:0005515	protein binding

0.58	GO:0016324	apical plasma membrane
0.57	GO:0030139	endocytic vesicle
0.54	GO:0005768	endosome
0.54	GO:0005794	Golgi apparatus
0.39	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0044433	cytoplasmic vesicle part
0.38	GO:0005765	lysosomal membrane
0.38	GO:0005789	endoplasmic reticulum membrane
0.37	GO:0070820	tertiary granule
0.37	GO:0042581	specific granule

0.83

EC:3.1.4.4

GO:0004630

sp|Q13394|MB211_HUMAN
Putative nucleotidyltransferase MAB21L1
Search

MAB21L1

0.96	Mab-21 like 1

0.81	GO:0043010	camera-type eye development
0.79	GO:0008284	positive regulation of cell proliferation
0.42	GO:0010172	embryonic body morphogenesis

0.61	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm

sp|Q13395|TARB1_HUMAN
Probable methyltransferase TARBP1
Search

TARBP1

0.95	TAR RNA-binding protein 1

0.68	GO:0001510	RNA methylation
0.62	GO:0006396	RNA processing
0.46	GO:0016072	rRNA metabolic process
0.46	GO:0042254	ribosome biogenesis
0.44	GO:0006399	tRNA metabolic process
0.36	GO:0006357	regulation of transcription by RNA polymerase II
0.32	GO:0006836	neurotransmitter transport
0.31	GO:0055085	transmembrane transport

0.68	GO:0008173	RNA methyltransferase activity
0.58	GO:0003723	RNA binding
0.48	GO:0008171	O-methyltransferase activity
0.48	GO:0140102	catalytic activity, acting on a rRNA
0.46	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity
0.45	GO:0140101	catalytic activity, acting on a tRNA
0.32	GO:0005328	neurotransmitter:sodium symporter activity

0.34	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.68

GO:0008173

sp|Q13398|ZN211_HUMAN
Zinc finger protein 211
Search

0.72	Zinc finger protein interacting with K protein 1

0.54	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.37	GO:1902679	negative regulation of RNA biosynthetic process
0.36	GO:0006351	transcription, DNA-templated

0.51	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.36	GO:0042802	identical protein binding

0.43	GO:0005622	intracellular
0.36	GO:0043227	membrane-bounded organelle
0.35	GO:0019013	viral nucleocapsid
0.34	GO:1990904	ribonucleoprotein complex

sp|Q13401|PM2P3_HUMAN
Putative postmeiotic segregation increased 2-like protein 3
Search

0.10	Putative postmeiotic segregation increased 2-like protein 3

0.67	GO:0006298	mismatch repair
0.52	GO:0016446	somatic hypermutation of immunoglobulin genes
0.48	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.45	GO:1903506	regulation of nucleic acid-templated transcription
0.45	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.45	GO:0010468	regulation of gene expression
0.40	GO:0045935	positive regulation of nucleobase-containing compound metabolic process
0.39	GO:0010604	positive regulation of macromolecule metabolic process
0.39	GO:0006366	transcription by RNA polymerase II
0.38	GO:0031328	positive regulation of cellular biosynthetic process

0.65	GO:0030983	mismatched DNA binding
0.55	GO:0032407	MutSalpha complex binding
0.51	GO:0003697	single-stranded DNA binding
0.49	GO:0032559	adenyl ribonucleotide binding
0.49	GO:0004519	endonuclease activity
0.48	GO:0008144	drug binding
0.48	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0046872	metal ion binding
0.41	GO:0016887	ATPase activity
0.40	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding

0.52	GO:0032389	MutLalpha complex
0.49	GO:0036464	cytoplasmic ribonucleoprotein granule
0.49	GO:0031981	nuclear lumen
0.46	GO:0015630	microtubule cytoskeleton
0.45	GO:0005829	cytosol
0.40	GO:0005886	plasma membrane

0.41

GO:0016887

sp|Q13402|MYO7A_HUMAN
Unconventional myosin-VIIa
Search

MYO7A

0.77	Unconventional myosin-VIIa

0.73	GO:0007018	microtubule-based movement
0.61	GO:0050957	equilibrioception
0.60	GO:0060122	inner ear receptor cell stereocilium organization
0.60	GO:0002093	auditory receptor cell morphogenesis
0.60	GO:0001845	phagolysosome assembly
0.59	GO:0051904	pigment granule transport
0.59	GO:0030048	actin filament-based movement
0.59	GO:0050954	sensory perception of mechanical stimulus
0.57	GO:0048563	post-embryonic animal organ morphogenesis
0.55	GO:0007601	visual perception

0.75	GO:0051015	actin filament binding
0.73	GO:0003777	microtubule motor activity
0.73	GO:0008017	microtubule binding
0.61	GO:0000146	microfilament motor activity
0.59	GO:0030507	spectrin binding
0.56	GO:0005516	calmodulin binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0019904	protein domain specific binding

0.76	GO:0016459	myosin complex
0.60	GO:0001917	photoreceptor inner segment
0.59	GO:0001750	photoreceptor outer segment
0.58	GO:0032391	photoreceptor connecting cilium
0.58	GO:0032420	stereocilium
0.58	GO:0042470	melanosome
0.57	GO:0005765	lysosomal membrane
0.56	GO:0016324	apical plasma membrane
0.54	GO:0045202	synapse
0.51	GO:0005829	cytosol

sp|Q13404|UB2V1_HUMAN
Ubiquitin-conjugating enzyme E2 variant 1
Search

UBE2V1

0.95	Ubiquitin-conjugating enzyme E2 variant 1

0.75	GO:0070534	protein K63-linked ubiquitination
0.73	GO:0006301	postreplication repair
0.60	GO:0000729	DNA double-strand break processing
0.56	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.55	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.43	GO:0006282	regulation of DNA repair
0.43	GO:0051965	positive regulation of synapse assembly
0.42	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.42	GO:2001022	positive regulation of response to DNA damage stimulus
0.42	GO:0043524	negative regulation of neuron apoptotic process

0.65	GO:0004842	ubiquitin-protein transferase activity
0.63	GO:0031625	ubiquitin protein ligase binding
0.63	GO:0061650	ubiquitin-like protein conjugating enzyme activity
0.61	GO:0061659	ubiquitin-like protein ligase activity
0.41	GO:0031624	ubiquitin conjugating enzyme binding
0.35	GO:0003678	DNA helicase activity
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0003677	DNA binding
0.33	GO:0097367	carbohydrate derivative binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.73	GO:0031371	ubiquitin conjugating enzyme complex
0.61	GO:0005654	nucleoplasm
0.54	GO:0000151	ubiquitin ligase complex
0.44	GO:0005737	cytoplasm
0.44	GO:0070062	extracellular exosome
0.37	GO:0042555	MCM complex
0.30	GO:0016020	membrane

0.65

GO:0004842

sp|Q13405|RM49_HUMAN
39S ribosomal protein L49, mitochondrial
Search

MRPL49

0.97	Mitochondrial ribosomal protein L49

0.60	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.35	GO:0043624	cellular protein complex disassembly

0.64	GO:0003735	structural constituent of ribosome
0.37	GO:0003743	translation initiation factor activity
0.34	GO:0005515	protein binding

0.61	GO:0005840	ribosome
0.54	GO:0005759	mitochondrial matrix
0.35	GO:0031966	mitochondrial membrane
0.35	GO:0019866	organelle inner membrane

sp|Q13409|DC1I2_HUMAN
Cytoplasmic dynein 1 intermediate chain 2
Search

DYNC1I2

0.94	Cytoplasmic dynein 1 intermediate chain 2

0.73	GO:0007018	microtubule-based movement
0.44	GO:2000582	positive regulation of ATP-dependent microtubule motor activity, plus-end-directed
0.42	GO:0030705	cytoskeleton-dependent intracellular transport
0.36	GO:0097711	ciliary basal body-plasma membrane docking
0.36	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.36	GO:1990090	cellular response to nerve growth factor stimulus
0.35	GO:0000086	G2/M transition of mitotic cell cycle
0.35	GO:0010977	negative regulation of neuron projection development
0.35	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.35	GO:0007420	brain development

0.44	GO:0045504	dynein heavy chain binding
0.44	GO:0045503	dynein light chain binding
0.43	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed
0.34	GO:0032403	protein complex binding

0.82	GO:0005868	cytoplasmic dynein complex
0.50	GO:0005813	centrosome
0.48	GO:0005874	microtubule
0.48	GO:0031982	vesicle
0.35	GO:0030426	growth cone
0.35	GO:0043025	neuronal cell body
0.35	GO:0030424	axon
0.34	GO:0005829	cytosol
0.33	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.43

EC:3.6.4.4

GO:0008574

sp|Q13410|BT1A1_HUMAN
Butyrophilin subfamily 1 member A1
Search

BTN1A1

0.82	Butyrophilin subfamily 1 member A1

0.47	GO:0046007	negative regulation of activated T cell proliferation
0.45	GO:0050710	negative regulation of cytokine secretion
0.40	GO:0031324	negative regulation of cellular metabolic process
0.40	GO:0045591	positive regulation of regulatory T cell differentiation
0.40	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling
0.40	GO:0050860	negative regulation of T cell receptor signaling pathway
0.40	GO:0051898	negative regulation of protein kinase B signaling
0.39	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle
0.39	GO:0070372	regulation of ERK1 and ERK2 cascade
0.37	GO:0051248	negative regulation of protein metabolic process

0.36	GO:0004872	receptor activity
0.35	GO:0005515	protein binding

0.43	GO:0005615	extracellular space
0.38	GO:0009986	cell surface
0.37	GO:0005887	integral component of plasma membrane
0.36	GO:1903561	extracellular vesicle

sp|Q13415|ORC1_HUMAN
Origin recognition complex subunit 1
Search

ORC1

0.87	LOW QUALITY PROTEIN: origin recognition complex subunit 1

0.43	GO:0006270	DNA replication initiation
0.40	GO:0051301	cell division
0.38	GO:0001878	response to yeast
0.37	GO:0040014	regulation of multicellular organism growth
0.37	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle
0.36	GO:0043009	chordate embryonic development
0.36	GO:0070318	positive regulation of G0 to G1 transition
0.36	GO:0048661	positive regulation of smooth muscle cell proliferation

0.75	GO:0003682	chromatin binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0005515	protein binding
0.35	GO:0003677	DNA binding
0.33	GO:0005509	calcium ion binding
0.32	GO:0016787	hydrolase activity

0.60	GO:0005664	nuclear origin of replication recognition complex
0.57	GO:0000784	nuclear chromosome, telomeric region
0.53	GO:0005730	nucleolus
0.50	GO:0005829	cytosol
0.44	GO:0005886	plasma membrane
0.35	GO:0005654	nucleoplasm
0.33	GO:1905369	endopeptidase complex

0.32

GO:0016787

sp|Q13416|ORC2_HUMAN
Origin recognition complex subunit 2
Search

ORC2

0.86	Origin recognition complex subunit 2

0.66	GO:0006260	DNA replication
0.35	GO:0000082	G1/S transition of mitotic cell cycle
0.35	GO:0000122	negative regulation of transcription by RNA polymerase II
0.34	GO:0000413	protein peptidyl-prolyl isomerization
0.33	GO:0006457	protein folding

0.57	GO:0003688	DNA replication origin binding
0.34	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.34	GO:0003682	chromatin binding
0.34	GO:0005515	protein binding

0.82	GO:0000808	origin recognition complex
0.61	GO:0005634	nucleus
0.60	GO:0000939	condensed chromosome inner kinetochore
0.57	GO:0000792	heterochromatin
0.55	GO:0000781	chromosome, telomeric region
0.55	GO:0005813	centrosome
0.51	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0003755

sp|Q13418|ILK_HUMAN
Integrin-linked protein kinase
Search

ILK

0.96	Integrin-linked protein kinase

0.72	GO:0007229	integrin-mediated signaling pathway
0.61	GO:0006468	protein phosphorylation
0.60	GO:0034446	substrate adhesion-dependent cell spreading
0.60	GO:0010761	fibroblast migration
0.58	GO:2000178	negative regulation of neural precursor cell proliferation
0.58	GO:0043491	protein kinase B signaling
0.58	GO:0032292	peripheral nervous system axon ensheathment
0.58	GO:0001658	branching involved in ureteric bud morphogenesis
0.58	GO:0014044	Schwann cell development
0.58	GO:1901224	positive regulation of NIK/NF-kappaB signaling

0.62	GO:0004672	protein kinase activity
0.54	GO:0019901	protein kinase binding
0.53	GO:0030554	adenyl nucleotide binding
0.52	GO:0097367	carbohydrate derivative binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0004871	signal transducer activity
0.39	GO:0005178	integrin binding
0.38	GO:0017124	SH3 domain binding

0.58	GO:0005925	focal adhesion
0.57	GO:0030027	lamellipodium
0.50	GO:0005654	nucleoplasm
0.49	GO:0097517	contractile actin filament bundle
0.49	GO:0042641	actomyosin
0.49	GO:0005829	cytosol
0.45	GO:0030017	sarcomere
0.40	GO:0042383	sarcolemma
0.39	GO:0043034	costamere
0.39	GO:0043198	dendritic shaft

sp|Q13421|MSLN_HUMAN
Mesothelin
Search

MSLN

0.94	Mesothelin

0.67	GO:0007160	cell-matrix adhesion
0.53	GO:0031016	pancreas development
0.47	GO:0006501	C-terminal protein lipidation

0.42

GO:0005515

protein binding

0.64	GO:0005615	extracellular space
0.62	GO:0009986	cell surface
0.51	GO:0031225	anchored component of membrane
0.47	GO:0005794	Golgi apparatus
0.46	GO:0005788	endoplasmic reticulum lumen
0.41	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q13422|IKZF1_HUMAN
DNA-binding protein Ikaros
Search

IKZF1

0.97	Ikaros transcription factor

0.58	GO:0030098	lymphocyte differentiation
0.56	GO:0051291	protein heterooligomerization
0.55	GO:0030218	erythrocyte differentiation
0.47	GO:0042113	B cell activation
0.46	GO:0042110	T cell activation
0.45	GO:0045944	positive regulation of transcription by RNA polymerase II
0.40	GO:0045660	positive regulation of neutrophil differentiation
0.39	GO:0060040	retinal bipolar neuron differentiation
0.39	GO:0051138	positive regulation of NK T cell differentiation
0.39	GO:0035881	amacrine cell differentiation

0.51	GO:0019904	protein domain specific binding
0.50	GO:0003676	nucleic acid binding
0.45	GO:0046872	metal ion binding
0.41	GO:0003700	DNA binding transcription factor activity
0.36	GO:0046982	protein heterodimerization activity

0.56	GO:0031618	nuclear pericentric heterochromatin
0.49	GO:0005654	nucleoplasm
0.44	GO:0043234	protein complex
0.37	GO:0032993	protein-DNA complex
0.33	GO:0005737	cytoplasm

sp|Q13423|NNTM_HUMAN
NAD(P) transhydrogenase, mitochondrial
Search

NNT

0.68	Nicotinamide nucleotide transhydrogenase

0.61	GO:0015992	proton transport
0.52	GO:0055114	oxidation-reduction process
0.48	GO:0072593	reactive oxygen species metabolic process
0.44	GO:0006739	NADP metabolic process
0.34	GO:0006101	citrate metabolic process
0.33	GO:0098662	inorganic cation transmembrane transport
0.33	GO:0006091	generation of precursor metabolites and energy

0.78	GO:0008746	NAD(P)+ transhydrogenase activity
0.49	GO:0050661	NADP binding
0.42	GO:0051287	NAD binding
0.33	GO:0015078	hydrogen ion transmembrane transporter activity

0.44	GO:0005739	mitochondrion
0.40	GO:0019866	organelle inner membrane
0.33	GO:0070469	respiratory chain
0.30	GO:0016021	integral component of membrane

0.78	EC:1.6.1	GO:0008746
0.78	KEGG:R00112	GO:0008746

sp|Q13424|SNTA1_HUMAN
Alpha-1-syntrophin
Search

SNTA1

0.93	59 kDa dystrophin-associated protein A1 acidic component 1

0.57	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation
0.55	GO:0086005	ventricular cardiac muscle cell action potential
0.55	GO:0060307	regulation of ventricular cardiac muscle cell membrane repolarization
0.54	GO:1902305	regulation of sodium ion transmembrane transport
0.53	GO:0002027	regulation of heart rate
0.45	GO:0065009	regulation of molecular function
0.43	GO:0050808	synapse organization
0.36	GO:0003116	regulation of vasoconstriction by norepinephrine
0.34	GO:0006400	tRNA modification

0.62	GO:0005198	structural molecule activity
0.56	GO:0050998	nitric-oxide synthase binding
0.54	GO:0017080	sodium channel regulator activity
0.54	GO:0051117	ATPase binding
0.53	GO:0044325	ion channel binding
0.40	GO:0030165	PDZ domain binding
0.37	GO:0005516	calmodulin binding
0.37	GO:0003779	actin binding
0.34	GO:0051539	4 iron, 4 sulfur cluster binding
0.32	GO:0016740	transferase activity

0.47	GO:0043234	protein complex
0.46	GO:0045202	synapse
0.39	GO:0044459	plasma membrane part
0.39	GO:0042383	sarcolemma
0.37	GO:0030054	cell junction
0.37	GO:0005622	intracellular
0.34	GO:0043228	non-membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.32

GO:0016740

sp|Q13425|SNTB2_HUMAN
Beta-2-syntrophin
Search

SNTB2

0.92	LOW QUALITY PROTEIN: beta-2-syntrophin

0.38	GO:0050808	synapse organization
0.36	GO:0006936	muscle contraction
0.35	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation
0.34	GO:0060307	regulation of ventricular cardiac muscle cell membrane repolarization
0.34	GO:0086001	cardiac muscle cell action potential
0.34	GO:1902305	regulation of sodium ion transmembrane transport
0.34	GO:0070252	actin-mediated cell contraction
0.34	GO:0002027	regulation of heart rate
0.34	GO:0060047	heart contraction
0.33	GO:0065009	regulation of molecular function

0.62	GO:0005198	structural molecule activity
0.39	GO:0005516	calmodulin binding
0.38	GO:0003779	actin binding
0.37	GO:0030165	PDZ domain binding
0.34	GO:0003723	RNA binding
0.34	GO:0050998	nitric-oxide synthase binding
0.34	GO:0017080	sodium channel regulator activity
0.34	GO:0051117	ATPase binding
0.34	GO:0044325	ion channel binding
0.34	GO:0032559	adenyl ribonucleotide binding

0.58	GO:0045202	synapse
0.49	GO:0043234	protein complex
0.40	GO:0005737	cytoplasm
0.40	GO:0030054	cell junction
0.38	GO:0070062	extracellular exosome
0.37	GO:0005856	cytoskeleton
0.37	GO:0012506	vesicle membrane
0.37	GO:0044459	plasma membrane part
0.36	GO:0097708	intracellular vesicle
0.36	GO:0099512	supramolecular fiber

0.32

GO:0016887

sp|Q13426|XRCC4_HUMAN
DNA repair protein XRCC4
Search

XRCC4

0.87	X-ray repair complementing defective repair in Chinese hamster cells 4

0.76	GO:0006302	double-strand break repair
0.74	GO:0051351	positive regulation of ligase activity
0.72	GO:0010165	response to X-ray
0.68	GO:0000726	non-recombinational repair
0.66	GO:0051103	DNA ligation involved in DNA repair
0.65	GO:0006310	DNA recombination
0.45	GO:0071285	cellular response to lithium ion
0.40	GO:0002328	pro-B cell differentiation
0.40	GO:1905765	negative regulation of protection from non-homologous end joining at telomere
0.40	GO:0002208	somatic diversification of immunoglobulins involved in immune response

0.68	GO:0008022	protein C-terminus binding
0.62	GO:0042802	identical protein binding
0.55	GO:0003677	DNA binding
0.40	GO:1990599	3' overhang single-stranded DNA endodeoxyribonuclease activity
0.35	GO:0016874	ligase activity

0.75	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex
0.74	GO:0032807	DNA ligase IV complex
0.61	GO:0005654	nucleoplasm
0.58	GO:0005829	cytosol
0.40	GO:0070522	ERCC4-ERCC1 complex
0.38	GO:0000784	nuclear chromosome, telomeric region
0.38	GO:0000793	condensed chromosome

0.35

GO:0016874

sp|Q13427|PPIG_HUMAN
Peptidyl-prolyl cis-trans isomerase G
Search

PPIG

0.96	Peptidyl-prolyl cis-trans isomerase G

0.71	GO:0000413	protein peptidyl-prolyl isomerization
0.66	GO:0006457	protein folding
0.35	GO:0008380	RNA splicing
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.71	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.37	GO:0016018	cyclosporin A binding
0.35	GO:0003723	RNA binding
0.34	GO:0005515	protein binding
0.32	GO:0003700	DNA binding transcription factor activity

0.58	GO:0016607	nuclear speck
0.51	GO:0005829	cytosol
0.41	GO:0016363	nuclear matrix
0.30	GO:0031224	intrinsic component of membrane

0.71

GO:0003755

sp|Q13428|TCOF_HUMAN
Treacle protein
Search

TCOF1

0.86	Treacle ribosome biogenesis factor 1

0.86	GO:0014029	neural crest formation
0.84	GO:0014032	neural crest cell development
0.71	GO:0006417	regulation of translation
0.49	GO:0042790	nucleolar large rRNA transcription by RNA polymerase I
0.36	GO:0001501	skeletal system development

0.86	GO:0001042	RNA polymerase I core binding
0.85	GO:0097110	scaffold protein binding
0.74	GO:0046982	protein heterodimerization activity
0.36	GO:0003723	RNA binding
0.33	GO:0005215	transporter activity

0.84	GO:0001650	fibrillar center
0.69	GO:0005829	cytosol

sp|Q13432|U119A_HUMAN
Protein unc-119 homolog A
Search

UNC119

0.97	Unc-119 lipid binding chaperone

0.74	GO:0007399	nervous system development
0.57	GO:0061098	positive regulation of protein tyrosine kinase activity
0.54	GO:0042953	lipoprotein transport
0.53	GO:0000281	mitotic cytokinesis
0.46	GO:0070121	Kupffer's vesicle development
0.45	GO:0007601	visual perception
0.44	GO:0030154	cell differentiation
0.43	GO:2001287	negative regulation of caveolin-mediated endocytosis
0.43	GO:1900186	negative regulation of clathrin-dependent endocytosis
0.38	GO:0006897	endocytosis

0.49	GO:0008289	lipid binding
0.35	GO:0005515	protein binding

0.55	GO:0045171	intercellular bridge
0.55	GO:0051233	spindle midzone
0.52	GO:0000922	spindle pole
0.52	GO:0005813	centrosome
0.34	GO:0005737	cytoplasm
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0031984	organelle subcompartment
0.33	GO:1902494	catalytic complex
0.32	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

sp|Q13433|S39A6_HUMAN
Zinc transporter ZIP6
Search

SLC39A6

0.91	Zinc transporter ZIP6

0.66	GO:0030001	metal ion transport
0.54	GO:0055085	transmembrane transport
0.51	GO:0006882	cellular zinc ion homeostasis
0.47	GO:0072511	divalent inorganic cation transport

0.68	GO:0046873	metal ion transmembrane transporter activity
0.48	GO:0072509	divalent inorganic cation transmembrane transporter activity

0.54	GO:0031258	lamellipodium membrane
0.45	GO:0005783	endoplasmic reticulum
0.44	GO:0005887	integral component of plasma membrane
0.40	GO:0009986	cell surface

sp|Q13434|MKRN4_HUMAN
Putative E3 ubiquitin-protein ligase makorin-4
Search

MKRN1

0.89	Makorin ring finger protein 1

0.55	GO:0000209	protein polyubiquitination
0.40	GO:1990830	cellular response to leukemia inhibitory factor

0.54	GO:0046872	metal ion binding
0.51	GO:0004842	ubiquitin-protein transferase activity
0.41	GO:0042802	identical protein binding
0.39	GO:0003682	chromatin binding
0.36	GO:0003723	RNA binding
0.33	GO:0016874	ligase activity

0.33	EC:6	GO:0016874
0.51	KEGG:R03876	GO:0004842

sp|Q13435|SF3B2_HUMAN
Splicing factor 3B subunit 2
Search

SF3B2

0.90	Splicing factor 3B subunit 2

0.46	GO:0000398	mRNA splicing, via spliceosome
0.34	GO:0016032	viral process

0.39	GO:0005515	protein binding
0.34	GO:0003723	RNA binding

0.61	GO:0005634	nucleus
0.47	GO:0070013	intracellular organelle lumen
0.47	GO:0120114	Sm-like protein family complex
0.46	GO:1902494	catalytic complex
0.46	GO:1990904	ribonucleoprotein complex
0.44	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

sp|Q13438|OS9_HUMAN
Protein OS-9
Search

OS9

0.97	Amplified in osteosarcoma

0.78	GO:1904153	negative regulation of retrograde protein transport, ER to cytosol
0.75	GO:0030433	ubiquitin-dependent ERAD pathway
0.73	GO:0006621	protein retention in ER lumen
0.72	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.60	GO:0030970	retrograde protein transport, ER to cytosol
0.42	GO:0006605	protein targeting
0.41	GO:1904380	endoplasmic reticulum mannose trimming
0.37	GO:1902358	sulfate transmembrane transport

0.49	GO:0030246	carbohydrate binding
0.45	GO:0002020	protease binding
0.38	GO:0008271	secondary active sulfate transmembrane transporter activity

0.76	GO:0005788	endoplasmic reticulum lumen
0.73	GO:0000836	Hrd1p ubiquitin ligase complex
0.41	GO:0044322	endoplasmic reticulum quality control compartment
0.30	GO:0031224	intrinsic component of membrane

sp|Q13439|GOGA4_HUMAN
Golgin subfamily A member 4
Search

GOLGA4

0.79	LOW QUALITY PROTEIN: golgin subfamily A member 4

0.85	GO:0045773	positive regulation of axon extension
0.84	GO:0043001	Golgi to plasma membrane protein transport
0.33	GO:0007229	integrin-mediated signaling pathway
0.33	GO:0007155	cell adhesion

0.73

GO:0051020

GTPase binding

0.71	GO:0005794	Golgi apparatus
0.68	GO:0005829	cytosol
0.45	GO:0070062	extracellular exosome
0.45	GO:0098588	bounding membrane of organelle
0.44	GO:0031984	organelle subcompartment
0.33	GO:0008305	integrin complex

sp|Q13442|HAP28_HUMAN
28 kDa heat- and acid-stable phosphoprotein
Search

PDAP1

0.95	PDGFA associated protein 1

0.41	GO:0043312	neutrophil degranulation
0.41	GO:0048008	platelet-derived growth factor receptor signaling pathway
0.39	GO:0008283	cell proliferation
0.37	GO:0070536	protein K63-linked deubiquitination
0.34	GO:0016310	phosphorylation

0.41	GO:0048407	platelet-derived growth factor binding
0.38	GO:0003723	RNA binding
0.37	GO:0061578	Lys63-specific deubiquitinase activity
0.34	GO:0016301	kinase activity

0.67	GO:0005829	cytosol
0.55	GO:0005886	plasma membrane
0.42	GO:1904813	ficolin-1-rich granule lumen
0.40	GO:0005576	extracellular region

sp|Q13443|ADAM9_HUMAN
Disintegrin and metalloproteinase domain-containing protein 9
Search

ADAM9

0.94	Disintegrin and metalloproteinase domain-containing protein 9

0.64	GO:0007229	integrin-mediated signaling pathway
0.60	GO:0006508	proteolysis
0.59	GO:0034241	positive regulation of macrophage fusion
0.59	GO:0042117	monocyte activation
0.59	GO:0033631	cell-cell adhesion mediated by integrin
0.58	GO:0010042	response to manganese ion
0.58	GO:0051549	positive regulation of keratinocyte migration
0.57	GO:0033630	positive regulation of cell adhesion mediated by integrin
0.56	GO:0030216	keratinocyte differentiation
0.55	GO:0051592	response to calcium ion

0.70	GO:0004222	metalloendopeptidase activity
0.57	GO:0043236	laminin binding
0.55	GO:0005178	integrin binding
0.54	GO:0005518	collagen binding
0.54	GO:0046872	metal ion binding
0.53	GO:0017124	SH3 domain binding
0.40	GO:0005080	protein kinase C binding
0.32	GO:0004252	serine-type endopeptidase activity
0.31	GO:0003723	RNA binding

0.40	GO:0031233	intrinsic component of external side of plasma membrane
0.39	GO:0016323	basolateral plasma membrane
0.38	GO:0005925	focal adhesion
0.38	GO:0070062	extracellular exosome
0.33	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

0.70

GO:0004222

sp|Q13444|ADA15_HUMAN
Disintegrin and metalloproteinase domain-containing protein 15
Search

ADAM15

0.87	LOW QUALITY PROTEIN: disintegrin and metalloproteinase domain-containing protein 15

0.71	GO:0007229	integrin-mediated signaling pathway
0.61	GO:0006508	proteolysis
0.59	GO:0002418	immune response to tumor cell
0.58	GO:0070528	protein kinase C signaling
0.57	GO:1900121	negative regulation of receptor binding
0.56	GO:0001953	negative regulation of cell-matrix adhesion
0.56	GO:0060317	cardiac epithelial to mesenchymal transition
0.54	GO:0030308	negative regulation of cell growth
0.54	GO:0030336	negative regulation of cell migration
0.52	GO:0045087	innate immune response

0.70	GO:0004222	metalloendopeptidase activity
0.58	GO:0017124	SH3 domain binding
0.55	GO:0005178	integrin binding
0.54	GO:0046872	metal ion binding
0.34	GO:0046875	ephrin receptor binding

0.53	GO:0070062	extracellular exosome
0.51	GO:0009986	cell surface
0.44	GO:0012505	endomembrane system
0.40	GO:0097223	sperm part
0.40	GO:0044444	cytoplasmic part
0.39	GO:0005912	adherens junction
0.39	GO:0043229	intracellular organelle
0.37	GO:0042995	cell projection
0.34	GO:0005886	plasma membrane
0.34	GO:0043233	organelle lumen

0.70

GO:0004222

sp|Q13445|TMED1_HUMAN
Transmembrane emp24 domain-containing protein 1
Search

TMED1

0.91	Transmembrane emp24 protein transport domain containing 1

0.48	GO:0090161	Golgi ribbon formation
0.39	GO:0015031	protein transport
0.34	GO:0007267	cell-cell signaling
0.33	GO:0007165	signal transduction

0.34

GO:0005102

receptor binding

0.60	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.52	GO:0005783	endoplasmic reticulum
0.50	GO:0005794	Golgi apparatus
0.45	GO:0005801	cis-Golgi network
0.40	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.40	GO:0044446	intracellular organelle part
0.40	GO:0098588	bounding membrane of organelle
0.36	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q13449|LSAMP_HUMAN
Limbic system-associated membrane protein
Search

LSAMP

0.85	Opioid-binding protein/cell adhesion molecule

0.64	GO:0035641	locomotory exploration behavior
0.44	GO:0007155	cell adhesion
0.41	GO:0007631	feeding behavior
0.41	GO:0007399	nervous system development
0.40	GO:0031346	positive regulation of cell projection organization
0.40	GO:0010720	positive regulation of cell development
0.40	GO:0051962	positive regulation of nervous system development
0.40	GO:0120035	regulation of plasma membrane bounded cell projection organization
0.38	GO:0030154	cell differentiation
0.38	GO:0006501	C-terminal protein lipidation

0.35

GO:0005515

protein binding

0.53	GO:0005829	cytosol
0.44	GO:0031225	anchored component of membrane
0.39	GO:0005886	plasma membrane
0.35	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

sp|Q13451|FKBP5_HUMAN
Peptidyl-prolyl cis-trans isomerase FKBP5
Search

FKBP5

0.65	Peptidyl-prolyl cis-trans isomerase FKBP5

0.79	GO:0061077	chaperone-mediated protein folding
0.72	GO:0000413	protein peptidyl-prolyl isomerization

0.85	GO:0005528	FK506 binding
0.78	GO:0031072	heat shock protein binding
0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity

0.60	GO:0005654	nucleoplasm
0.50	GO:0070062	extracellular exosome
0.49	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.72

GO:0003755

sp|Q13454|TUSC3_HUMAN
Tumor suppressor candidate 3
Search

TUSC3

0.96	Tumor suppressor candidate 3

0.57	GO:0018279	protein N-linked glycosylation via asparagine
0.55	GO:0015693	magnesium ion transport
0.54	GO:0050890	cognition
0.45	GO:0098662	inorganic cation transmembrane transport

0.51	GO:0015095	magnesium ion transmembrane transporter activity
0.49	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity

0.56	GO:0008250	oligosaccharyltransferase complex
0.43	GO:0005739	mitochondrion
0.34	GO:0005887	integral component of plasma membrane

0.49

EC:2.4.1.119

GO:0004579

sp|Q13459|MYO9B_HUMAN
Unconventional myosin-IXb
Search

MYO9B

0.91	Unconventional myosin-IXb

0.76	GO:0043547	positive regulation of GTPase activity
0.74	GO:0007018	microtubule-based movement
0.63	GO:0035556	intracellular signal transduction
0.57	GO:0035385	Roundabout signaling pathway
0.56	GO:0030048	actin filament-based movement
0.52	GO:0035023	regulation of Rho protein signal transduction
0.35	GO:0072673	lamellipodium morphogenesis
0.35	GO:0048246	macrophage chemotaxis
0.34	GO:0002548	monocyte chemotaxis
0.34	GO:0030010	establishment of cell polarity

0.76	GO:0005096	GTPase activator activity
0.74	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.73	GO:0003779	actin binding
0.59	GO:0048495	Roundabout binding
0.58	GO:0000146	microfilament motor activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0005516	calmodulin binding

0.76	GO:0016459	myosin complex
0.55	GO:0005884	actin filament
0.53	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0005938	cell cortex
0.49	GO:0005829	cytosol
0.34	GO:0032433	filopodium tip
0.34	GO:0001726	ruffle
0.34	GO:0030027	lamellipodium
0.30	GO:0031224	intrinsic component of membrane

0.44

GO:0016887

sp|Q13461|FOXE3_HUMAN
Forkhead box protein E3
Search

FOXE3

0.88	Winged helix protein CWH-1

0.57	GO:0006355	regulation of transcription, DNA-templated
0.52	GO:0002088	lens development in camera-type eye
0.51	GO:0009653	anatomical structure morphogenesis
0.51	GO:2001109	regulation of lens epithelial cell proliferation
0.51	GO:1902747	negative regulation of lens fiber cell differentiation
0.50	GO:0002930	trabecular meshwork development
0.49	GO:0061303	cornea development in camera-type eye
0.48	GO:0030154	cell differentiation
0.47	GO:0042789	mRNA transcription by RNA polymerase II
0.47	GO:0050679	positive regulation of epithelial cell proliferation

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.35	GO:0001012	RNA polymerase II regulatory region DNA binding
0.34	GO:0003690	double-stranded DNA binding
0.34	GO:0001106	RNA polymerase II transcription corepressor activity
0.34	GO:0008301	DNA binding, bending

0.61	GO:0005634	nucleus
0.43	GO:0005667	transcription factor complex

sp|Q13464|ROCK1_HUMAN
Rho-associated protein kinase 1
Search

ROCK1

0.92	Rho associated coiled-coil containing protein kinase 1

0.84	GO:0007266	Rho protein signal transduction
0.84	GO:0051492	regulation of stress fiber assembly
0.77	GO:2000114	regulation of establishment of cell polarity
0.68	GO:0030036	actin cytoskeleton organization
0.63	GO:0006468	protein phosphorylation
0.55	GO:0051451	myoblast migration
0.54	GO:0051894	positive regulation of focal adhesion assembly
0.54	GO:1903347	negative regulation of bicellular tight junction assembly
0.54	GO:0140058	neuron projection arborization
0.54	GO:0032060	bleb assembly

0.85	GO:0017049	GTP-Rho binding
0.70	GO:0004674	protein serine/threonine kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0046872	metal ion binding
0.39	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity

0.59	GO:0005856	cytoskeleton
0.53	GO:0106003	amyloid-beta complex
0.52	GO:0001726	ruffle
0.52	GO:0030027	lamellipodium
0.42	GO:0032059	bleb
0.41	GO:0005886	plasma membrane
0.38	GO:0000139	Golgi membrane
0.35	GO:0034774	secretory granule lumen
0.35	GO:0005829	cytosol
0.35	GO:0036464	cytoplasmic ribonucleoprotein granule

0.70

GO:0004674

sp|Q13467|FZD5_HUMAN
Frizzled-5
Search

FZD5

0.95	Frizzled class receptor 5

0.72	GO:0016055	Wnt signaling pathway
0.69	GO:0007275	multicellular organism development
0.57	GO:0060061	Spemann organizer formation
0.56	GO:0002726	positive regulation of T cell cytokine production
0.55	GO:1901382	regulation of chorionic trophoblast cell proliferation
0.55	GO:1903146	regulation of autophagy of mitochondrion
0.55	GO:0060718	chorionic trophoblast cell differentiation
0.54	GO:0032729	positive regulation of interferon-gamma production
0.54	GO:1903955	positive regulation of protein targeting to mitochondrion
0.54	GO:0060828	regulation of canonical Wnt signaling pathway

0.70	GO:0004888	transmembrane signaling receptor activity
0.61	GO:0017147	Wnt-protein binding
0.54	GO:0001540	amyloid-beta binding
0.53	GO:0031625	ubiquitin protein ligase binding
0.51	GO:0019901	protein kinase binding
0.39	GO:0030165	PDZ domain binding
0.35	GO:0005102	receptor binding

0.56	GO:0106003	amyloid-beta complex
0.50	GO:0005923	bicellular tight junction
0.50	GO:0005769	early endosome
0.50	GO:0009986	cell surface
0.49	GO:0048471	perinuclear region of cytoplasm
0.46	GO:0005794	Golgi apparatus
0.46	GO:0005887	integral component of plasma membrane
0.38	GO:1990851	Wnt-Frizzled-LRP5/6 complex
0.36	GO:0098588	bounding membrane of organelle
0.36	GO:0031984	organelle subcompartment

sp|Q13469|NFAC2_HUMAN
Nuclear factor of activated T-cells, cytoplasmic 2
Search

NFATC2

0.96	Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2

0.59	GO:0033173	calcineurin-NFAT signaling cascade
0.59	GO:1901741	positive regulation of myoblast fusion
0.58	GO:0030890	positive regulation of B cell proliferation
0.57	GO:0050853	B cell receptor signaling pathway
0.57	GO:0014904	myotube cell development
0.56	GO:0001816	cytokine production
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0016477	cell migration

0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.53	GO:0003682	chromatin binding
0.51	GO:0008134	transcription factor binding

0.52	GO:0044798	nuclear transcription factor complex
0.52	GO:0000790	nuclear chromatin
0.49	GO:0005654	nucleoplasm
0.49	GO:0005829	cytosol
0.45	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q13470|TNK1_HUMAN
Non-receptor tyrosine-protein kinase TNK1
Search

TNK1

0.88	Tyrosine kinase non receptor 1

0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.58	GO:0046777	protein autophosphorylation
0.57	GO:0046580	negative regulation of Ras protein signal transduction
0.57	GO:0030308	negative regulation of cell growth
0.48	GO:0045087	innate immune response
0.48	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.48	GO:0016477	cell migration
0.47	GO:0030154	cell differentiation
0.47	GO:0042127	regulation of cell proliferation
0.44	GO:2000369	regulation of clathrin-dependent endocytosis

0.76	GO:0004713	protein tyrosine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0004712	protein serine/threonine/tyrosine kinase activity
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0005102	receptor binding
0.42	GO:0031625	ubiquitin protein ligase binding
0.41	GO:0042169	SH2 domain binding
0.40	GO:0042802	identical protein binding
0.35	GO:0004871	signal transducer activity

0.49	GO:0005829	cytosol
0.49	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.45	GO:0030136	clathrin-coated vesicle
0.45	GO:0070436	Grb2-EGFR complex
0.42	GO:0005905	clathrin-coated pit
0.38	GO:0005634	nucleus
0.37	GO:0005912	adherens junction
0.35	GO:0030055	cell-substrate junction
0.34	GO:0030659	cytoplasmic vesicle membrane
0.34	GO:0005768	endosome

0.76

EC:2.7.10

GO:0004713

sp|Q13472|TOP3A_HUMAN
DNA topoisomerase 3-alpha
Search

TOP3A

0.55	DNA topoisomerase

0.72	GO:0006265	DNA topological change
0.36	GO:0000732	strand displacement
0.36	GO:1901796	regulation of signal transduction by p53 class mediator
0.35	GO:0000731	DNA synthesis involved in DNA repair
0.35	GO:0051321	meiotic cell cycle
0.34	GO:0006260	DNA replication
0.33	GO:0045892	negative regulation of transcription, DNA-templated

0.77	GO:0003917	DNA topoisomerase type I activity
0.62	GO:0008270	zinc ion binding
0.55	GO:0003677	DNA binding
0.33	GO:0005515	protein binding

0.67	GO:0005694	chromosome
0.56	GO:0016605	PML body
0.30	GO:0031224	intrinsic component of membrane

0.77

EC:5.99.1.2

GO:0003917

sp|Q13474|DRP2_HUMAN
Dystrophin-related protein 2
Search

DRP2

0.82	Dystrophin-related protein 2 isoform 1

0.63

GO:0008270

zinc ion binding

0.36

GO:0005886

plasma membrane

sp|Q13477|MADCA_HUMAN
Mucosal addressin cell adhesion molecule 1
Search

MADCAM1

0.97	Mucosal vascular addressin cell adhesion molecule 1 transcript variant 1

0.86	GO:2000403	positive regulation of lymphocyte migration
0.82	GO:0007160	cell-matrix adhesion
0.80	GO:0007229	integrin-mediated signaling pathway
0.61	GO:0050901	leukocyte tethering or rolling
0.60	GO:0034113	heterotypic cell-cell adhesion
0.57	GO:0043113	receptor clustering
0.40	GO:0030198	extracellular matrix organization
0.39	GO:0030216	keratinocyte differentiation
0.39	GO:0006955	immune response
0.39	GO:0007568	aging

0.87

GO:0098640

integrin binding involved in cell-matrix adhesion

0.42	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q13478|IL18R_HUMAN
Interleukin-18 receptor 1
Search

IL18R1

0.97	Interleukin-18 receptor alpha chain

0.69	GO:0019221	cytokine-mediated signaling pathway
0.63	GO:0071351	cellular response to interleukin-18
0.63	GO:0045063	T-helper 1 cell differentiation
0.61	GO:0042346	positive regulation of NF-kappaB import into nucleus
0.60	GO:0030101	natural killer cell activation
0.60	GO:0001819	positive regulation of cytokine production
0.60	GO:0032649	regulation of interferon-gamma production
0.47	GO:0042094	interleukin-2 biosynthetic process
0.46	GO:0072602	interleukin-4 secretion
0.46	GO:0032674	regulation of interleukin-5 production

0.70	GO:0004896	cytokine receptor activity
0.44	GO:1990782	protein tyrosine kinase binding
0.35	GO:0002113	interleukin-33 binding
0.34	GO:0005161	platelet-derived growth factor receptor binding
0.33	GO:0019966	interleukin-1 binding
0.33	GO:0002020	protease binding

0.41	GO:0005615	extracellular space
0.35	GO:0005886	plasma membrane
0.34	GO:0009986	cell surface
0.34	GO:0098552	side of membrane
0.33	GO:0005578	proteinaceous extracellular matrix
0.30	GO:0016021	integral component of membrane

sp|Q13480|GAB1_HUMAN
GRB2-associated-binding protein 1
Search

GAB1

0.77	GRB2-associated-binding protein 1

0.30	GO:0001525	angiogenesis
0.30	GO:0032868	response to insulin
0.30	GO:0051270	regulation of cellular component movement
0.30	GO:0008654	phospholipid biosynthetic process
0.30	GO:0040011	locomotion
0.30	GO:0040012	regulation of locomotion
0.30	GO:0035728	response to hepatocyte growth factor
0.30	GO:0030182	neuron differentiation
0.30	GO:0032989	cellular component morphogenesis
0.30	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway

0.30	GO:0060090	molecular adaptor activity
0.30	GO:0005515	protein binding
0.30	GO:0052813	phosphatidylinositol bisphosphate kinase activity
0.30	GO:0035004	phosphatidylinositol 3-kinase activity
0.30	GO:0052742	phosphatidylinositol kinase activity

0.30

GO:0044464

cell part

0.30

GO:0052813

sp|Q13485|SMAD4_HUMAN
Mothers against decapentaplegic homolog 4
Search

SMAD4

0.65	Mothers against decapentaplegic homolog

0.82	GO:0007179	transforming growth factor beta receptor signaling pathway
0.60	GO:0003251	positive regulation of cell proliferation involved in heart valve morphogenesis
0.60	GO:1905305	negative regulation of cardiac myofibril assembly
0.60	GO:0061040	female gonad morphogenesis
0.60	GO:0003220	left ventricular cardiac muscle tissue morphogenesis
0.60	GO:0072134	nephrogenic mesenchyme morphogenesis
0.59	GO:0046881	positive regulation of follicle-stimulating hormone secretion
0.59	GO:0033686	positive regulation of luteinizing hormone secretion
0.59	GO:0072133	metanephric mesenchyme morphogenesis
0.59	GO:0003360	brainstem development

0.61	GO:0003700	DNA binding transcription factor activity
0.60	GO:0030616	transforming growth factor beta receptor, common-partner cytoplasmic mediator activity
0.59	GO:0043199	sulfate binding
0.57	GO:0070411	I-SMAD binding
0.57	GO:0070412	R-SMAD binding
0.55	GO:0001085	RNA polymerase II transcription factor binding
0.54	GO:0005518	collagen binding
0.54	GO:0003677	DNA binding
0.52	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.52	GO:0003682	chromatin binding

0.74	GO:0005667	transcription factor complex
0.61	GO:0005634	nucleus
0.58	GO:0071141	SMAD protein complex
0.52	GO:0005813	centrosome
0.49	GO:0000785	chromatin
0.48	GO:0005737	cytoplasm
0.47	GO:0070013	intracellular organelle lumen
0.30	GO:0031224	intrinsic component of membrane

sp|Q13487|SNPC2_HUMAN
snRNA-activating protein complex subunit 2
Search

SNAPC2

0.95	Small nuclear RNA activating complex polypeptide 2

0.41

GO:0035622

intrahepatic bile duct development

0.77	GO:0016604	nuclear body
0.68	GO:0005829	cytosol

sp|Q13488|VPP3_HUMAN
V-type proton ATPase 116 kDa subunit a isoform 3
Search

TCIRG1

0.58	V-type proton ATPase subunit a

0.76	GO:0015991	ATP hydrolysis coupled proton transport
0.59	GO:0007039	protein catabolic process in the vacuole
0.54	GO:0016236	macroautophagy
0.50	GO:0007035	vacuolar acidification
0.49	GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly
0.44	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.44	GO:0006754	ATP biosynthetic process
0.36	GO:0090383	phagosome acidification
0.36	GO:0006968	cellular defense response
0.36	GO:0033572	transferrin transport

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.50	GO:0051117	ATPase binding
0.48	GO:0036442	proton-exporting ATPase activity
0.45	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
0.35	GO:0051539	4 iron, 4 sulfur cluster binding
0.35	GO:0016651	oxidoreductase activity, acting on NAD(P)H

0.80	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain
0.55	GO:0016324	apical plasma membrane
0.49	GO:0016471	vacuolar proton-transporting V-type ATPase complex
0.45	GO:0005739	mitochondrion
0.39	GO:0005765	lysosomal membrane
0.37	GO:0031410	cytoplasmic vesicle
0.36	GO:0012505	endomembrane system
0.36	GO:0031526	brush border membrane
0.35	GO:0012506	vesicle membrane
0.34	GO:0005887	integral component of plasma membrane

0.35

EC:1.6

GO:0016651

sp|Q13489|BIRC3_HUMAN
Baculoviral IAP repeat-containing protein 3
Search

0.92	Inhibitor of apoptosis protein (Fragment)

0.74	GO:0042981	regulation of apoptotic process
0.41	GO:0060546	negative regulation of necroptotic process
0.41	GO:0097340	inhibition of cysteine-type endopeptidase activity
0.40	GO:0034121	regulation of toll-like receptor signaling pathway
0.40	GO:0090307	mitotic spindle assembly
0.38	GO:0006915	apoptotic process
0.38	GO:0016567	protein ubiquitination

0.40	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.38	GO:0004842	ubiquitin-protein transferase activity
0.34	GO:0046872	metal ion binding

0.36	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm

0.38

GO:0004842

sp|Q13490|BIRC2_HUMAN
Baculoviral IAP repeat-containing protein 2
Search

0.85	Inhibitor of apoptosis protein 1

0.74	GO:0042981	regulation of apoptotic process
0.42	GO:0060546	negative regulation of necroptotic process
0.42	GO:0097340	inhibition of cysteine-type endopeptidase activity
0.41	GO:0034121	regulation of toll-like receptor signaling pathway
0.41	GO:0090307	mitotic spindle assembly
0.40	GO:0006915	apoptotic process
0.39	GO:0016567	protein ubiquitination

0.42	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.39	GO:0004842	ubiquitin-protein transferase activity
0.35	GO:0046872	metal ion binding

0.36	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm

0.39

GO:0004842

sp|Q13491|GPM6B_HUMAN
Neuronal membrane glycoprotein M6-b
Search

GPM6B

0.94	Neuronal membrane glycoprotein M6-b

0.47	GO:0030501	positive regulation of bone mineralization
0.47	GO:0051893	regulation of focal adhesion assembly
0.47	GO:0085029	extracellular matrix assembly
0.44	GO:0032956	regulation of actin cytoskeleton organization
0.40	GO:0051612	negative regulation of serotonin uptake
0.40	GO:2000009	negative regulation of protein localization to cell surface
0.38	GO:0001503	ossification
0.37	GO:0007399	nervous system development
0.37	GO:0030154	cell differentiation
0.36	GO:0015031	protein transport

0.38	GO:0045121	membrane raft
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q13492|PICAL_HUMAN
Phosphatidylinositol-binding clathrin assembly protein
Search

PICALM

0.86	Phosphatidylinositol-binding clathrin assembly protein isoform 1

0.82	GO:0048268	clathrin coat assembly
0.71	GO:0006897	endocytosis
0.58	GO:0097753	membrane bending
0.58	GO:1902963	negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
0.58	GO:1900223	positive regulation of amyloid-beta clearance
0.58	GO:1902959	regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
0.58	GO:0097494	regulation of vesicle size
0.57	GO:1902004	positive regulation of amyloid-beta formation
0.57	GO:1905247	positive regulation of aspartic-type peptidase activity
0.57	GO:0090647	modulation of age-related behavioral decline

0.83	GO:0005545	1-phosphatidylinositol binding
0.80	GO:0030276	clathrin binding
0.55	GO:0050750	low-density lipoprotein particle receptor binding
0.55	GO:0098748	endocytic adaptor activity
0.53	GO:0045296	cadherin binding
0.52	GO:0017137	Rab GTPase binding
0.37	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.35	GO:0017124	SH3 domain binding
0.34	GO:0042802	identical protein binding
0.33	GO:0003735	structural constituent of ribosome

0.79	GO:0030136	clathrin-coated vesicle
0.58	GO:0070381	endosome to plasma membrane transport vesicle
0.57	GO:0097418	neurofibrillary tangle
0.54	GO:0030666	endocytic vesicle membrane
0.53	GO:0005905	clathrin-coated pit
0.52	GO:0043025	neuronal cell body
0.52	GO:0005769	early endosome
0.52	GO:0048471	perinuclear region of cytoplasm
0.52	GO:0030131	clathrin adaptor complex
0.51	GO:0030120	vesicle coat

sp|Q13495|MAMD1_HUMAN
Mastermind-like domain-containing protein 1
Search

MAMLD1

0.66	Mastermind-like domain-containing protein 1

0.76	GO:0008584	male gonad development
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression

0.70	GO:0005813	centrosome
0.70	GO:0016604	nuclear body
0.65	GO:0005794	Golgi apparatus

sp|Q13496|MTM1_HUMAN
Myotubularin
Search

MTM1

0.96	Myotubularin

0.85	GO:0045109	intermediate filament organization
0.85	GO:0046716	muscle cell cellular homeostasis
0.85	GO:0008333	endosome to lysosome transport
0.84	GO:0044088	regulation of vacuole organization
0.83	GO:0048311	mitochondrion distribution
0.81	GO:0046856	phosphatidylinositol dephosphorylation
0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.58	GO:0048633	positive regulation of skeletal muscle tissue growth
0.56	GO:0070584	mitochondrion morphogenesis
0.55	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process

0.85	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity
0.85	GO:0004438	phosphatidylinositol-3-phosphatase activity
0.74	GO:0004725	protein tyrosine phosphatase activity
0.57	GO:0019215	intermediate filament binding
0.51	GO:0035091	phosphatidylinositol binding
0.35	GO:0042803	protein homodimerization activity
0.34	GO:0008138	protein tyrosine/serine/threonine phosphatase activity

0.55	GO:0030175	filopodium
0.54	GO:0001726	ruffle
0.53	GO:0031674	I band
0.53	GO:0005770	late endosome
0.47	GO:0005829	cytosol
0.42	GO:0005886	plasma membrane
0.37	GO:0070062	extracellular exosome
0.35	GO:0005774	vacuolar membrane
0.34	GO:0043197	dendritic spine
0.34	GO:0031901	early endosome membrane

0.85

GO:0052629

sp|Q13501|SQSTM_HUMAN
Sequestosome-1
Search

SQSTM1

0.88	Sequestosome-1

0.64	GO:1905719	protein localization to perinuclear region of cytoplasm
0.63	GO:0035973	aggrephagy
0.62	GO:0061635	regulation of protein complex stability
0.62	GO:0000423	mitophagy
0.62	GO:1900273	positive regulation of long-term synaptic potentiation
0.61	GO:0098780	response to mitochondrial depolarisation
0.61	GO:0044130	negative regulation of growth of symbiont in host
0.59	GO:1903078	positive regulation of protein localization to plasma membrane
0.59	GO:0007032	endosome organization
0.59	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling

0.63	GO:0008270	zinc ion binding
0.62	GO:0042169	SH2 domain binding
0.62	GO:0005080	protein kinase C binding
0.61	GO:0035255	ionotropic glutamate receptor binding
0.60	GO:0070530	K63-linked polyubiquitin modification-dependent protein binding
0.60	GO:0043130	ubiquitin binding
0.56	GO:0031625	ubiquitin protein ligase binding
0.54	GO:0042802	identical protein binding
0.37	GO:0046983	protein dimerization activity
0.36	GO:0030971	receptor tyrosine kinase binding

0.63	GO:0044753	amphisome
0.61	GO:0016235	aggresome
0.61	GO:0044754	autolysosome
0.60	GO:0097225	sperm midpiece
0.59	GO:0016605	PML body
0.57	GO:0000932	P-body
0.57	GO:0000407	phagophore assembly site
0.50	GO:0005829	cytosol
0.42	GO:0097413	Lewy body
0.41	GO:0030017	sarcomere

sp|Q13503|MED21_HUMAN
Mediator of RNA polymerase II transcription subunit 21
Search

MED21

0.92	Mediator of RNA polymerase II transcription subunit 21

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.53	GO:0019827	stem cell population maintenance
0.52	GO:0001824	blastocyst development
0.47	GO:1902680	positive regulation of RNA biosynthetic process
0.37	GO:0016567	protein ubiquitination

0.53	GO:0003712	transcription cofactor activity
0.49	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.38	GO:0061630	ubiquitin protein ligase activity
0.35	GO:0005515	protein binding
0.34	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.32	GO:0016787	hydrolase activity

0.77	GO:0016592	mediator complex
0.38	GO:0000151	ubiquitin ligase complex

0.34

EC:2.7.7.6

GO:0003899

sp|Q13505|MTX1_HUMAN
Metaxin-1
Search

MTX1

0.88

Metaxin

0.78	GO:0006626	protein targeting to mitochondrion
0.41	GO:0007595	lactation
0.32	GO:0030198	extracellular matrix organization
0.32	GO:0007155	cell adhesion

0.32	GO:0008201	heparin binding
0.32	GO:0005509	calcium ion binding

0.77	GO:0005741	mitochondrial outer membrane
0.36	GO:0019866	organelle inner membrane
0.32	GO:0031012	extracellular matrix
0.30	GO:0031224	intrinsic component of membrane

sp|Q13506|NAB1_HUMAN
NGFI-A-binding protein 1
Search

NAB1

0.97	NGFI-A-binding protein 1

0.72	GO:0045892	negative regulation of transcription, DNA-templated
0.62	GO:0001958	endochondral ossification
0.61	GO:0014037	Schwann cell differentiation
0.60	GO:0045682	regulation of epidermis development
0.59	GO:0042552	myelination
0.37	GO:0006351	transcription, DNA-templated

0.53

GO:0008134

transcription factor binding

0.61

GO:0005634

nucleus

sp|Q13507|TRPC3_HUMAN
Short transient receptor potential channel 3
Search

TRPC3

0.97	LOW QUALITY PROTEIN: short transient receptor potential channel 3

0.76	GO:0070588	calcium ion transmembrane transport
0.61	GO:1903244	positive regulation of cardiac muscle hypertrophy in response to stress
0.58	GO:0010524	positive regulation of calcium ion transport into cytosol
0.57	GO:0033198	response to ATP
0.57	GO:0051592	response to calcium ion
0.52	GO:0006828	manganese ion transport
0.49	GO:0007338	single fertilization
0.37	GO:0030168	platelet activation
0.35	GO:0007602	phototransduction

0.78	GO:0005262	calcium channel activity
0.57	GO:0070679	inositol 1,4,5 trisphosphate binding
0.35	GO:0005515	protein binding
0.35	GO:0005227	calcium activated cation channel activity

0.50	GO:0005887	integral component of plasma membrane
0.38	GO:0005801	cis-Golgi network
0.38	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0005635	nuclear envelope

sp|Q13508|NAR3_HUMAN
Ecto-ADP-ribosyltransferase 3
Search

ART3

0.75	Ecto-ADP-ribosyltransferase 3

0.83	GO:0006471	protein ADP-ribosylation
0.37	GO:0006501	C-terminal protein lipidation

0.85	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity
0.41	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.41	GO:0003953	NAD+ nucleosidase activity

0.40	GO:0070062	extracellular exosome
0.38	GO:0031225	anchored component of membrane
0.35	GO:0005887	integral component of plasma membrane

0.85

EC:2.4.2.31

GO:0003956

sp|Q13509|TBB3_HUMAN
Tubulin beta-3 chain
Search

0.49	Tubulin beta chain

0.72	GO:0007017	microtubule-based process
0.71	GO:0007010	cytoskeleton organization
0.46	GO:0007411	axon guidance
0.44	GO:0007186	G-protein coupled receptor signaling pathway
0.36	GO:0000278	mitotic cell cycle
0.34	GO:0006915	apoptotic process
0.33	GO:0035556	intracellular signal transduction

0.77	GO:0005200	structural constituent of cytoskeleton
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0004930	G-protein coupled receptor activity
0.37	GO:0042277	peptide binding
0.35	GO:0042288	MHC class I protein binding
0.34	GO:0031625	ubiquitin protein ligase binding

0.73	GO:0005874	microtubule
0.45	GO:0044297	cell body
0.45	GO:0030425	dendrite
0.45	GO:0030424	axon
0.43	GO:0005737	cytoplasm
0.38	GO:0071944	cell periphery
0.37	GO:0070062	extracellular exosome
0.35	GO:0005634	nucleus
0.34	GO:0031970	organelle envelope lumen
0.34	GO:0035770	ribonucleoprotein granule

sp|Q13510|ASAH1_HUMAN
Acid ceramidase
Search

ASAH1

0.90	N-acylsphingosine amidohydrolase

0.61	GO:0006629	lipid metabolic process
0.49	GO:0048668	collateral sprouting

0.65

GO:0017040

ceramidase activity

0.76	GO:0005764	lysosome
0.55	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

0.65

EC:3.5.1.23

GO:0017040

sp|Q13515|BFSP2_HUMAN
Phakinin
Search

BFSP2

0.97	Beaded filament structural protein 2

0.85	GO:0045104	intermediate filament cytoskeleton organization
0.65	GO:0070307	lens fiber cell development
0.60	GO:0048469	cell maturation
0.38	GO:0007601	visual perception
0.34	GO:0050896	response to stimulus

0.63	GO:0005212	structural constituent of eye lens
0.36	GO:0005200	structural constituent of cytoskeleton
0.35	GO:0005515	protein binding

0.79	GO:0005882	intermediate filament
0.41	GO:0005737	cytoplasm
0.35	GO:0005886	plasma membrane

sp|Q13516|OLIG2_HUMAN
Oligodendrocyte transcription factor 2
Search

OLIG2

0.91	Oligodendrocyte lineage transcription factor 2

0.83	GO:0001708	cell fate specification
0.78	GO:0021779	oligodendrocyte cell fate commitment
0.76	GO:0030182	neuron differentiation
0.74	GO:0021517	ventral spinal cord development
0.73	GO:0021515	cell differentiation in spinal cord
0.72	GO:0042552	myelination
0.58	GO:0048714	positive regulation of oligodendrocyte differentiation
0.57	GO:0000122	negative regulation of transcription by RNA polymerase II
0.57	GO:0021794	thalamus development
0.54	GO:0045665	negative regulation of neuron differentiation

0.67	GO:0046983	protein dimerization activity
0.57	GO:0071837	HMG box domain binding
0.57	GO:0140110	transcription regulator activity
0.50	GO:0042802	identical protein binding
0.36	GO:0003677	DNA binding

0.45	GO:0005634	nucleus
0.39	GO:0005737	cytoplasm
0.36	GO:0005667	transcription factor complex

sp|Q13519|PNOC_HUMAN
Prepronociceptin
Search

PNOC

0.78	Prepronociceptin

0.79	GO:0007218	neuropeptide signaling pathway
0.76	GO:0098916	anterograde trans-synaptic signaling
0.52	GO:0010469	regulation of receptor activity
0.41	GO:0007600	sensory perception
0.40	GO:0007565	female pregnancy

0.60	GO:0001515	opioid peptide activity
0.46	GO:0031628	opioid receptor binding
0.44	GO:0005184	neuropeptide hormone activity

0.48	GO:0005576	extracellular region
0.44	GO:0043679	axon terminus
0.43	GO:0043025	neuronal cell body
0.43	GO:0030425	dendrite
0.37	GO:0005886	plasma membrane

sp|Q13520|AQP6_HUMAN
Aquaporin-6
Search

0.90	Water channel protein AQP-xt5a

0.59	GO:0042476	odontogenesis
0.58	GO:0006833	water transport
0.55	GO:0055085	transmembrane transport
0.51	GO:0050878	regulation of body fluid levels
0.50	GO:0015670	carbon dioxide transport
0.49	GO:0032941	secretion by tissue
0.48	GO:0003008	system process
0.48	GO:0071288	cellular response to mercury ion
0.47	GO:0007586	digestion
0.47	GO:0048593	camera-type eye morphogenesis

0.69	GO:0022803	passive transmembrane transporter activity
0.58	GO:0005372	water transmembrane transporter activity
0.47	GO:0015168	glycerol transmembrane transporter activity
0.44	GO:0042802	identical protein binding
0.38	GO:0015112	nitrate transmembrane transporter activity

0.57	GO:0016324	apical plasma membrane
0.49	GO:0009925	basal plasma membrane
0.48	GO:0005902	microvillus
0.46	GO:0012505	endomembrane system
0.45	GO:0070062	extracellular exosome
0.44	GO:0005887	integral component of plasma membrane
0.43	GO:0031410	cytoplasmic vesicle
0.39	GO:0043231	intracellular membrane-bounded organelle
0.39	GO:0012506	vesicle membrane
0.36	GO:0098805	whole membrane

sp|Q13522|PPR1A_HUMAN
Protein phosphatase 1 regulatory subunit 1A
Search

PPP1R1A

0.96	Phosphatase 1, regulatory (Inhibitor) subunit 1B

0.83	GO:0032515	negative regulation of phosphoprotein phosphatase activity
0.61	GO:0007165	signal transduction
0.49	GO:0006469	negative regulation of protein kinase activity
0.41	GO:0005977	glycogen metabolic process
0.35	GO:0006470	protein dephosphorylation

0.83	GO:0004864	protein phosphatase inhibitor activity
0.35	GO:0005515	protein binding
0.35	GO:0004721	phosphoprotein phosphatase activity

0.38	GO:0005615	extracellular space
0.37	GO:0005737	cytoplasm
0.35	GO:0099512	supramolecular fiber
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

0.35

GO:0004721

sp|Q13523|PRP4B_HUMAN
Serine/threonine-protein kinase PRP4 homolog
Search

PRPF4B

0.89	Pre-mRNA processing factor 4Ba

0.63	GO:0006468	protein phosphorylation
0.38	GO:0008380	RNA splicing
0.37	GO:0006397	mRNA processing

0.64	GO:0004672	protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0060089	molecular transducer activity
0.34	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.52	GO:0071013	catalytic step 2 spliceosome
0.52	GO:0016607	nuclear speck
0.46	GO:0005694	chromosome
0.30	GO:0031224	intrinsic component of membrane

sp|Q13526|PIN1_HUMAN
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Search

PIN1

0.48	Peptidyl-prolyl cis-trans isomerase

0.72	GO:0000413	protein peptidyl-prolyl isomerization
0.54	GO:0042177	negative regulation of protein catabolic process
0.54	GO:0060393	regulation of pathway-restricted SMAD protein phosphorylation
0.54	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.53	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.53	GO:0032091	negative regulation of protein binding
0.53	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.52	GO:0051443	positive regulation of ubiquitin-protein transferase activity
0.52	GO:1900180	regulation of protein localization to nucleus
0.52	GO:2000146	negative regulation of cell motility

0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.57	GO:0050816	phosphothreonine residue binding
0.55	GO:0031434	mitogen-activated protein kinase kinase binding
0.55	GO:0032794	GTPase activating protein binding
0.55	GO:0050815	phosphoserine residue binding
0.53	GO:0008013	beta-catenin binding
0.37	GO:0000993	RNA polymerase II core binding
0.36	GO:0003774	motor activity
0.34	GO:0008378	galactosyltransferase activity
0.33	GO:0016491	oxidoreductase activity

0.52	GO:0030496	midbody
0.47	GO:0005654	nucleoplasm
0.36	GO:0043005	neuron projection
0.36	GO:0005737	cytoplasm
0.33	GO:0012505	endomembrane system
0.30	GO:0016020	membrane

0.72

GO:0003755

sp|Q13530|SERC3_HUMAN
Serine incorporator 3
Search

SERINC3

0.89	Tumor differentially expressed protein 1

0.84	GO:0006658	phosphatidylserine metabolic process
0.78	GO:0006665	sphingolipid metabolic process
0.59	GO:0009597	detection of virus
0.58	GO:1902237	positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
0.52	GO:0045087	innate immune response
0.52	GO:0051607	defense response to virus
0.50	GO:0015825	L-serine transport
0.36	GO:1904219	positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity
0.36	GO:1904222	positive regulation of serine C-palmitoyltransferase activity
0.35	GO:0006564	L-serine biosynthetic process

0.50	GO:0015194	L-serine transmembrane transporter activity
0.36	GO:0030674	protein binding, bridging
0.34	GO:0019899	enzyme binding

0.58	GO:0012505	endomembrane system
0.54	GO:0031984	organelle subcompartment
0.49	GO:0043231	intracellular membrane-bounded organelle
0.49	GO:0044444	cytoplasmic part
0.43	GO:0005886	plasma membrane
0.37	GO:0098588	bounding membrane of organelle
0.30	GO:0016021	integral component of membrane

sp|Q13535|ATR_HUMAN
Serine/threonine-protein kinase ATR
Search

ATR

0.79	Serine/threonine-protein kinase ATR

0.67	GO:1904884	positive regulation of telomerase catalytic core complex assembly
0.67	GO:0097694	establishment of RNA localization to telomere
0.65	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator
0.64	GO:0070198	protein localization to chromosome, telomeric region
0.64	GO:0090399	replicative senescence
0.63	GO:0071480	cellular response to gamma radiation
0.61	GO:0006468	protein phosphorylation
0.61	GO:0034644	cellular response to UV
0.60	GO:0018209	peptidyl-serine modification
0.59	GO:0008156	negative regulation of DNA replication

0.68	GO:0004674	protein serine/threonine kinase activity
0.66	GO:0032407	MutSalpha complex binding
0.66	GO:0032405	MutLalpha complex binding
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0003677	DNA binding
0.34	GO:0046982	protein heterodimerization activity

0.62	GO:0016605	PML body
0.54	GO:0005794	Golgi apparatus
0.39	GO:0001741	XY body
0.36	GO:0000784	nuclear chromosome, telomeric region
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0004674

sp|Q13536|CROC4_HUMAN
Protein CROC-4
Search

sp|Q13541|4EBP1_HUMAN
Eukaryotic translation initiation factor 4E-binding protein 1
Search

EIF4EBP1

0.93	Eukaryotic translation initiation factor 4E-binding protein 1

0.82	GO:0045947	negative regulation of translational initiation
0.62	GO:0006413	translational initiation
0.54	GO:0031929	TOR signaling
0.52	GO:0000082	G1/S transition of mitotic cell cycle
0.51	GO:0045931	positive regulation of mitotic cell cycle
0.49	GO:0008286	insulin receptor signaling pathway
0.45	GO:0071549	cellular response to dexamethasone stimulus
0.43	GO:0035176	social behavior
0.43	GO:0007613	memory
0.42	GO:0019933	cAMP-mediated signaling

0.86	GO:0008190	eukaryotic initiation factor 4E binding
0.61	GO:0003743	translation initiation factor activity
0.57	GO:0030371	translation repressor activity
0.37	GO:0051721	protein phosphatase 2A binding

0.49	GO:0005829	cytosol
0.34	GO:0005634	nucleus
0.34	GO:0043234	protein complex

sp|Q13542|4EBP2_HUMAN
Eukaryotic translation initiation factor 4E-binding protein 2
Search

EIF4EBP2

0.92	Eukaryotic translation initiation factor 4E binding protein 2

0.82	GO:0045947	negative regulation of translational initiation
0.61	GO:0006413	translational initiation
0.52	GO:0008286	insulin receptor signaling pathway
0.52	GO:0031929	TOR signaling
0.52	GO:0035176	social behavior
0.51	GO:0007613	memory
0.51	GO:0019933	cAMP-mediated signaling
0.51	GO:0048167	regulation of synaptic plasticity
0.40	GO:0000082	G1/S transition of mitotic cell cycle
0.40	GO:0045931	positive regulation of mitotic cell cycle

0.86	GO:0008190	eukaryotic initiation factor 4E binding
0.61	GO:0003743	translation initiation factor activity
0.54	GO:0030371	translation repressor activity
0.35	GO:0051721	protein phosphatase 2A binding

0.40	GO:0005829	cytosol
0.33	GO:0005634	nucleus
0.33	GO:0043234	protein complex

sp|Q13546|RIPK1_HUMAN
Receptor-interacting serine/threonine-protein kinase 1
Search

RIPK1

0.97	Receptor-interacting serine/threonine-protein kinase 1

0.67	GO:0097343	ripoptosome assembly
0.66	GO:0060545	positive regulation of necroptotic process
0.66	GO:0097527	necroptotic signaling pathway
0.66	GO:0070926	regulation of ATP:ADP antiporter activity
0.65	GO:1990000	amyloid fibril formation
0.64	GO:0070231	T cell apoptotic process
0.64	GO:0036289	peptidyl-serine autophosphorylation
0.63	GO:1905206	positive regulation of hydrogen peroxide-induced cell death
0.63	GO:0045651	positive regulation of macrophage differentiation
0.62	GO:0051291	protein heterooligomerization

0.65	GO:0005123	death receptor binding
0.63	GO:0004672	protein kinase activity
0.62	GO:0070513	death domain binding
0.57	GO:0031625	ubiquitin protein ligase binding
0.54	GO:0032403	protein complex binding
0.54	GO:0030554	adenyl nucleotide binding
0.54	GO:0042802	identical protein binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding

0.65	GO:0097342	ripoptosome
0.63	GO:0031264	death-inducing signaling complex
0.56	GO:0043235	receptor complex
0.47	GO:0005739	mitochondrion
0.41	GO:0098857	membrane microdomain
0.36	GO:0010008	endosome membrane
0.30	GO:0016021	integral component of membrane

sp|Q13547|HDAC1_HUMAN
Histone deacetylase 1
Search

HDAC1

0.52	Histone deacetylase

0.79	GO:0016575	histone deacetylation
0.55	GO:0006346	methylation-dependent chromatin silencing
0.55	GO:0010870	positive regulation of receptor biosynthetic process
0.55	GO:0043922	negative regulation by host of viral transcription
0.55	GO:0060766	negative regulation of androgen receptor signaling pathway
0.54	GO:0006351	transcription, DNA-templated
0.52	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.51	GO:0042127	regulation of cell proliferation
0.50	GO:0000122	negative regulation of transcription by RNA polymerase II
0.48	GO:0045944	positive regulation of transcription by RNA polymerase II

0.80	GO:0004407	histone deacetylase activity
0.73	GO:0034979	NAD-dependent protein deacetylase activity
0.54	GO:0051059	NF-kappaB binding
0.54	GO:0001103	RNA polymerase II repressing transcription factor binding
0.53	GO:0001106	RNA polymerase II transcription corepressor activity
0.53	GO:0047485	protein N-terminus binding
0.53	GO:0046872	metal ion binding
0.52	GO:0033613	activating transcription factor binding
0.52	GO:0002039	p53 binding
0.52	GO:0042826	histone deacetylase binding

0.57	GO:0005634	nucleus
0.51	GO:0017053	transcriptional repressor complex
0.48	GO:0000785	chromatin
0.46	GO:0070013	intracellular organelle lumen
0.46	GO:0005829	cytosol
0.45	GO:1904949	ATPase complex
0.43	GO:0043025	neuronal cell body
0.42	GO:0043234	protein complex
0.39	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0043005	neuron projection

0.80

EC:3.5.1.98

GO:0004407

sp|Q13554|KCC2B_HUMAN
Calcium/calmodulin-dependent protein kinase type II subunit beta
Search

CAMK2B

0.64	Calcium/calmodulin-dependent protein kinase type II subunit beta

0.63	GO:0006468	protein phosphorylation
0.51	GO:0018210	peptidyl-threonine modification
0.50	GO:0018209	peptidyl-serine modification
0.45	GO:0007399	nervous system development
0.44	GO:0030154	cell differentiation
0.43	GO:0035556	intracellular signal transduction
0.30	GO:0043269	regulation of ion transport
0.30	GO:0042221	response to chemical
0.30	GO:0010769	regulation of cell morphogenesis involved in differentiation
0.30	GO:1900034	regulation of cellular response to heat

0.81	GO:0004683	calmodulin-dependent protein kinase activity
0.77	GO:0005516	calmodulin binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0042803	protein homodimerization activity
0.30	GO:0098772	molecular function regulator
0.30	GO:0031267	small GTPase binding
0.30	GO:0008092	cytoskeletal protein binding

0.46	GO:0043005	neuron projection
0.36	GO:0005737	cytoplasm
0.30	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.30	GO:0016021	integral component of membrane
0.30	GO:0098588	bounding membrane of organelle
0.30	GO:0031974	membrane-enclosed lumen
0.30	GO:0031984	organelle subcompartment
0.30	GO:0031982	vesicle
0.30	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0043232	intracellular non-membrane-bounded organelle

0.81

EC:2.7.11.17

GO:0004683

sp|Q13555|KCC2G_HUMAN
Calcium/calmodulin-dependent protein kinase type II subunit gamma
Search

CAMK2G

0.82	Calcium/calmodulin-dependent protein kinase type II subunit gamma

0.63	GO:0006468	protein phosphorylation
0.56	GO:1901897	regulation of relaxation of cardiac muscle
0.52	GO:0000082	G1/S transition of mitotic cell cycle
0.49	GO:0006816	calcium ion transport
0.48	GO:0051259	protein oligomerization
0.45	GO:0018210	peptidyl-threonine modification
0.45	GO:0018209	peptidyl-serine modification
0.43	GO:0007399	nervous system development
0.42	GO:0030154	cell differentiation
0.40	GO:0035556	intracellular signal transduction

0.82	GO:0004683	calmodulin-dependent protein kinase activity
0.78	GO:0005516	calmodulin binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0042803	protein homodimerization activity
0.37	GO:0004723	calcium-dependent protein serine/threonine phosphatase activity
0.36	GO:0004707	MAP kinase activity
0.36	GO:0005088	Ras guanyl-nucleotide exchange factor activity

0.52	GO:0014069	postsynaptic density
0.43	GO:0043005	neuron projection
0.37	GO:0033017	sarcoplasmic reticulum membrane
0.37	GO:0030666	endocytic vesicle membrane
0.35	GO:0005654	nucleoplasm
0.35	GO:0005829	cytosol
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.82	EC:2.7.11.17	GO:0004683
0.36	KEGG:R00162	GO:0004707

sp|Q13557|KCC2D_HUMAN
Calcium/calmodulin-dependent protein kinase type II subunit delta
Search

CAMK2D

0.94	Calcium/calmodulin-dependent protein kinase type II subunit delta

0.63	GO:0006468	protein phosphorylation
0.47	GO:0018210	peptidyl-threonine modification
0.46	GO:0018209	peptidyl-serine modification
0.43	GO:0007399	nervous system development
0.43	GO:0030154	cell differentiation
0.42	GO:0010613	positive regulation of cardiac muscle hypertrophy
0.41	GO:1901897	regulation of relaxation of cardiac muscle
0.41	GO:0055119	relaxation of cardiac muscle
0.40	GO:0086003	cardiac muscle cell contraction
0.40	GO:0060341	regulation of cellular localization

0.81	GO:0004683	calmodulin-dependent protein kinase activity
0.77	GO:0005516	calmodulin binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0008144	drug binding
0.40	GO:0044325	ion channel binding
0.39	GO:0031432	titin binding
0.39	GO:0019871	sodium channel inhibitor activity
0.38	GO:0050998	nitric-oxide synthase binding

0.44	GO:0043005	neuron projection
0.41	GO:0033017	sarcoplasmic reticulum membrane
0.41	GO:0042383	sarcolemma
0.39	GO:0034704	calcium channel complex
0.37	GO:0014704	intercalated disc
0.36	GO:0031594	neuromuscular junction
0.36	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0005829	cytosol
0.36	GO:0043025	neuronal cell body
0.36	GO:0005634	nucleus

0.81	EC:2.7.11.17	GO:0004683
0.34	KEGG:R00162	GO:0004707

sp|Q13561|DCTN2_HUMAN
Dynactin subunit 2
Search

DCTN2

0.96	Dynactin complex 50 kDa subunit

0.70	GO:0007017	microtubule-based process
0.55	GO:0032402	melanosome transport
0.55	GO:0071539	protein localization to centrosome
0.52	GO:0008283	cell proliferation
0.51	GO:0000278	mitotic cell cycle
0.43	GO:0007010	cytoskeleton organization
0.43	GO:0022402	cell cycle process
0.36	GO:0097711	ciliary basal body-plasma membrane docking
0.36	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.35	GO:0030719	P granule organization

0.54	GO:0030507	spectrin binding
0.51	GO:0019901	protein kinase binding
0.49	GO:0042802	identical protein binding
0.41	GO:0003774	motor activity

0.80	GO:0005869	dynactin complex
0.54	GO:0030426	growth cone
0.53	GO:0005813	centrosome
0.51	GO:0000776	kinetochore
0.50	GO:0031982	vesicle
0.47	GO:0005829	cytosol
0.42	GO:0030286	dynein complex
0.41	GO:0005874	microtubule
0.37	GO:0043230	extracellular organelle
0.36	GO:0005615	extracellular space

sp|Q13562|NDF1_HUMAN
Neurogenic differentiation factor 1
Search

NEUROD1

0.90	Neurogenic differentiation factor

0.74	GO:0048699	generation of neurons
0.69	GO:0048468	cell development
0.64	GO:0051960	regulation of nervous system development
0.64	GO:0060284	regulation of cell development
0.60	GO:0003312	pancreatic PP cell differentiation
0.60	GO:0003326	pancreatic A cell fate commitment
0.60	GO:0060730	regulation of intestinal epithelial structure maintenance
0.60	GO:0021549	cerebellum development
0.59	GO:0021542	dentate gyrus development
0.59	GO:2000675	negative regulation of type B pancreatic cell apoptotic process

0.68	GO:0046983	protein dimerization activity
0.62	GO:0070888	E-box binding
0.58	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.57	GO:0001105	RNA polymerase II transcription coactivator activity
0.57	GO:0001102	RNA polymerase II activating transcription factor binding
0.55	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.52	GO:0003682	chromatin binding
0.44	GO:0003714	transcription corepressor activity
0.33	GO:0008484	sulfuric ester hydrolase activity

0.59	GO:0005634	nucleus
0.52	GO:0005667	transcription factor complex
0.43	GO:0044446	intracellular organelle part
0.39	GO:0005737	cytoplasm
0.35	GO:0070013	intracellular organelle lumen

0.33

EC:3.1.6

GO:0008484

sp|Q13563|PKD2_HUMAN
Polycystin-2
Search

PKD2

0.94	Polycystin 2, transient receptor potential cation channel

0.61	GO:0072059	cortical collecting duct development
0.61	GO:0072055	renal cortex development
0.61	GO:0051284	positive regulation of sequestering of calcium ion
0.60	GO:0071464	cellular response to hydrostatic pressure
0.60	GO:0061441	renal artery morphogenesis
0.60	GO:0072208	metanephric smooth muscle tissue development
0.60	GO:0003127	detection of nodal flow
0.60	GO:0031587	positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
0.60	GO:0072218	metanephric ascending thin limb development
0.59	GO:0035502	metanephric part of ureteric bud development

0.70	GO:0005509	calcium ion binding
0.60	GO:0048763	calcium-induced calcium release activity
0.60	GO:0043398	HLH domain binding
0.58	GO:0015271	outward rectifier potassium channel activity
0.56	GO:0044325	ion channel binding
0.55	GO:0005248	voltage-gated sodium channel activity
0.55	GO:0051117	ATPase binding
0.55	GO:0051219	phosphoprotein binding
0.55	GO:0042805	actinin binding
0.54	GO:0005245	voltage-gated calcium channel activity

0.59	GO:0002133	polycystin complex
0.58	GO:0045180	basal cortex
0.58	GO:0016323	basolateral plasma membrane
0.57	GO:0071458	integral component of cytoplasmic side of endoplasmic reticulum membrane
0.57	GO:0071556	integral component of lumenal side of endoplasmic reticulum membrane
0.56	GO:0031941	filamentous actin
0.56	GO:0060170	ciliary membrane
0.55	GO:0036064	ciliary basal body
0.54	GO:0030027	lamellipodium
0.54	GO:0097730	non-motile cilium

0.32

GO:0016887

sp|Q13564|ULA1_HUMAN
NEDD8-activating enzyme E1 regulatory subunit
Search

NAE1

0.73	NEDD8-activating enzyme E1 regulatory subunit

0.83	GO:0045116	protein neddylation
0.56	GO:0051402	neuron apoptotic process
0.55	GO:0033314	mitotic DNA replication checkpoint
0.54	GO:0043523	regulation of neuron apoptotic process
0.35	GO:0043687	post-translational protein modification
0.34	GO:0007018	microtubule-based movement
0.33	GO:0007165	signal transduction

0.83	GO:0019781	NEDD8 activating enzyme activity
0.52	GO:0031625	ubiquitin protein ligase binding
0.50	GO:0046982	protein heterodimerization activity
0.34	GO:0003777	microtubule motor activity

0.36	GO:0005737	cytoplasm
0.35	GO:0005868	cytoplasmic dynein complex
0.35	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q13568|IRF5_HUMAN
Interferon regulatory factor 5
Search

IRF5

0.94	Interferon regulatory factor 5

0.74	GO:0019221	cytokine-mediated signaling pathway
0.73	GO:0051607	defense response to virus
0.67	GO:0006357	regulation of transcription by RNA polymerase II
0.62	GO:0032494	response to peptidoglycan
0.61	GO:0032495	response to muramyl dipeptide
0.56	GO:0006351	transcription, DNA-templated
0.56	GO:0043065	positive regulation of apoptotic process
0.55	GO:0045893	positive regulation of transcription, DNA-templated
0.44	GO:0043616	keratinocyte proliferation
0.44	GO:0060644	mammary gland epithelial cell differentiation

0.74	GO:0044212	transcription regulatory region DNA binding
0.60	GO:0003700	DNA binding transcription factor activity
0.53	GO:0042802	identical protein binding
0.50	GO:0043565	sequence-specific DNA binding

0.59	GO:0005634	nucleus
0.41	GO:0005737	cytoplasm
0.40	GO:0030054	cell junction
0.34	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

sp|Q13569|TDG_HUMAN
G/T mismatch-specific thymine DNA glycosylase
Search

TDG

0.93	LOW QUALITY PROTEIN: G/T mismatch-specific thymine DNA glycosylase

0.63	GO:0006281	DNA repair
0.62	GO:1902544	regulation of DNA N-glycosylase activity
0.60	GO:0035562	negative regulation of chromatin binding
0.57	GO:0032091	negative regulation of protein binding
0.57	GO:0080111	DNA demethylation
0.54	GO:0040029	regulation of gene expression, epigenetic
0.53	GO:0000122	negative regulation of transcription by RNA polymerase II
0.52	GO:0009790	embryo development
0.38	GO:0009223	pyrimidine deoxyribonucleotide catabolic process
0.36	GO:0016569	covalent chromatin modification

0.72	GO:0019104	DNA N-glycosylase activity
0.59	GO:0031404	chloride ion binding
0.59	GO:0032183	SUMO binding
0.58	GO:0005080	protein kinase C binding
0.58	GO:0043621	protein self-association
0.55	GO:0031402	sodium ion binding
0.54	GO:0001104	RNA polymerase II transcription cofactor activity
0.53	GO:0030983	mismatched DNA binding
0.52	GO:0042803	protein homodimerization activity
0.47	GO:0000287	magnesium ion binding

0.57	GO:0016605	PML body
0.43	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.72

EC:3.2.2

GO:0019104

sp|Q13571|LAPM5_HUMAN
Lysosomal-associated transmembrane protein 5
Search

LAPTM5

0.97	Lysosomal-associated transmembrane protein 5

0.62	GO:1990823	response to leukemia inhibitory factor
0.58	GO:0071345	cellular response to cytokine stimulus

0.36	GO:0005201	extracellular matrix structural constituent
0.35	GO:0005509	calcium ion binding
0.34	GO:0005515	protein binding

0.79	GO:0005764	lysosome
0.41	GO:0098852	lytic vacuole membrane
0.36	GO:0005578	proteinaceous extracellular matrix
0.34	GO:0005887	integral component of plasma membrane

sp|Q13572|ITPK1_HUMAN
Inositol-tetrakisphosphate 1-kinase
Search

ITPK1

0.77	Inositol-tetrakisphosphate 1-kinase b

0.85	GO:0032957	inositol trisphosphate metabolic process
0.57	GO:0016310	phosphorylation
0.55	GO:0021915	neural tube development
0.35	GO:0007596	blood coagulation
0.34	GO:0016311	dephosphorylation
0.33	GO:0007165	signal transduction

0.85	GO:0052726	inositol-1,3,4-trisphosphate 5-kinase activity
0.85	GO:0047325	inositol tetrakisphosphate 1-kinase activity
0.85	GO:0052725	inositol-1,3,4-trisphosphate 6-kinase activity
0.64	GO:0000287	magnesium ion binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0016853	isomerase activity
0.37	GO:0052831	inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity
0.37	GO:0052830	inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity

0.54	GO:0016324	apical plasma membrane
0.45	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

0.85	EC:2.7.1.159	GO:0052726
0.85	KEGG:R03428	GO:0052726

sp|Q13573|SNW1_HUMAN
SNW domain-containing protein 1
Search

SNW1

0.94	SNW domain-containing protein 1

0.72	GO:0000398	mRNA splicing, via spliceosome
0.48	GO:0090100	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
0.47	GO:0090287	regulation of cellular response to growth factor stimulus
0.47	GO:0006357	regulation of transcription by RNA polymerase II
0.47	GO:0014029	neural crest formation
0.44	GO:0022618	ribonucleoprotein complex assembly
0.42	GO:0070562	regulation of vitamin D receptor signaling pathway
0.41	GO:0048385	regulation of retinoic acid receptor signaling pathway
0.41	GO:0051571	positive regulation of histone H3-K4 methylation
0.41	GO:0048026	positive regulation of mRNA splicing, via spliceosome

0.45	GO:0003712	transcription cofactor activity
0.42	GO:0042809	vitamin D receptor binding
0.41	GO:0042974	retinoic acid receptor binding
0.41	GO:0046332	SMAD binding
0.39	GO:0050681	androgen receptor binding
0.39	GO:0005112	Notch binding
0.36	GO:0019899	enzyme binding
0.34	GO:0003723	RNA binding

0.73	GO:0005681	spliceosomal complex
0.50	GO:0071141	SMAD protein complex
0.48	GO:0005654	nucleoplasm
0.41	GO:0019908	nuclear cyclin-dependent protein kinase holoenzyme complex
0.40	GO:0016363	nuclear matrix
0.40	GO:0032806	carboxy-terminal domain protein kinase complex
0.36	GO:0000785	chromatin
0.33	GO:0005737	cytoplasm

sp|Q13574|DGKZ_HUMAN
Diacylglycerol kinase zeta
Search

DGKZ

0.49	Diacylglycerol kinase zeta

0.83	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway
0.62	GO:0035556	intracellular signal transduction
0.57	GO:0016310	phosphorylation
0.54	GO:0046339	diacylglycerol metabolic process
0.47	GO:0030258	lipid modification
0.39	GO:0031571	mitotic G1 DNA damage checkpoint
0.37	GO:0046580	negative regulation of Ras protein signal transduction
0.35	GO:0030168	platelet activation
0.35	GO:0043086	negative regulation of catalytic activity
0.35	GO:0016477	cell migration

0.80	GO:0004143	diacylglycerol kinase activity
0.75	GO:0003951	NAD+ kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0001727	lipid kinase activity
0.38	GO:0008022	protein C-terminus binding
0.35	GO:0004857	enzyme inhibitor activity
0.34	GO:0046872	metal ion binding

0.51	GO:0030027	lamellipodium
0.51	GO:0016607	nuclear speck
0.34	GO:0005886	plasma membrane
0.33	GO:0005737	cytoplasm

0.80	EC:2.7.1.107	GO:0004143
0.75	KEGG:R00104	GO:0003951

sp|Q13576|IQGA2_HUMAN
Ras GTPase-activating-like protein IQGAP2
Search

IQGAP2

0.90	Ras GTPase-activating-like protein IQGAP2

0.75	GO:0043087	regulation of GTPase activity
0.61	GO:0007165	signal transduction
0.46	GO:0034314	Arp2/3 complex-mediated actin nucleation
0.40	GO:0043312	neutrophil degranulation
0.38	GO:0051346	negative regulation of hydrolase activity
0.36	GO:0007596	blood coagulation
0.36	GO:0048519	negative regulation of biological process
0.32	GO:0003094	glomerular filtration
0.32	GO:0072015	glomerular visceral epithelial cell development
0.32	GO:0000278	mitotic cell cycle

0.48	GO:0071933	Arp2/3 complex binding
0.47	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.47	GO:0048365	Rac GTPase binding
0.45	GO:0005516	calmodulin binding
0.45	GO:0051015	actin filament binding
0.41	GO:0005095	GTPase inhibitor activity
0.37	GO:0015057	thrombin-activated receptor activity

0.47	GO:0031941	filamentous actin
0.47	GO:0030175	filopodium
0.46	GO:0030027	lamellipodium
0.46	GO:0005902	microvillus
0.44	GO:0009986	cell surface
0.40	GO:0005874	microtubule
0.39	GO:0030667	secretory granule membrane
0.39	GO:0070062	extracellular exosome
0.37	GO:0005829	cytosol
0.35	GO:0005886	plasma membrane

sp|Q13585|MTR1L_HUMAN
Melatonin-related receptor
Search

GPR50

0.97	G protein-coupled receptor 50

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.39	GO:0007267	cell-cell signaling

0.85	GO:0008502	melatonin receptor activity
0.64	GO:0042802	identical protein binding

0.61	GO:0005654	nucleoplasm
0.50	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q13586|STIM1_HUMAN
Stromal interaction molecule 1
Search

STIM1

0.93	Stromal interaction molecule 1

0.86	GO:0032237	activation of store-operated calcium channel activity
0.57	GO:0002115	store-operated calcium entry
0.50	GO:0014902	myotube differentiation
0.46	GO:0006874	cellular calcium ion homeostasis
0.41	GO:2001256	regulation of store-operated calcium entry
0.41	GO:0070166	enamel mineralization
0.41	GO:0005513	detection of calcium ion
0.39	GO:0045766	positive regulation of angiogenesis
0.37	GO:0070588	calcium ion transmembrane transport
0.36	GO:1903779	regulation of cardiac conduction

0.85	GO:0005246	calcium channel regulator activity
0.47	GO:0042802	identical protein binding
0.43	GO:0005509	calcium ion binding
0.40	GO:0051010	microtubule plus-end binding
0.39	GO:0015279	store-operated calcium channel activity
0.39	GO:0002020	protease binding

0.78	GO:0030176	integral component of endoplasmic reticulum membrane
0.41	GO:0043234	protein complex
0.40	GO:0033017	sarcoplasmic reticulum membrane
0.39	GO:0032541	cortical endoplasmic reticulum
0.38	GO:0005886	plasma membrane
0.38	GO:0030426	growth cone
0.38	GO:0005874	microtubule

sp|Q13588|GRAP_HUMAN
GRB2-related adapter protein
Search

GRB2

0.86	Growth factor receptor bound protein 2

0.83	GO:0007265	Ras protein signal transduction
0.58	GO:0008286	insulin receptor signaling pathway
0.56	GO:0031623	receptor internalization
0.56	GO:0071479	cellular response to ionizing radiation
0.56	GO:0042770	signal transduction in response to DNA damage
0.56	GO:2000379	positive regulation of reactive oxygen species metabolic process
0.53	GO:0060670	branching involved in labyrinthine layer morphogenesis
0.52	GO:0030838	positive regulation of actin filament polymerization
0.52	GO:0043408	regulation of MAPK cascade
0.52	GO:0030154	cell differentiation

0.60	GO:0043560	insulin receptor substrate binding
0.59	GO:0005154	epidermal growth factor receptor binding
0.59	GO:0005168	neurotrophin TRKA receptor binding
0.56	GO:0001784	phosphotyrosine residue binding
0.56	GO:0046875	ephrin receptor binding
0.55	GO:0005070	SH3/SH2 adaptor activity
0.54	GO:0019903	protein phosphatase binding
0.53	GO:0017124	SH3 domain binding
0.52	GO:0019901	protein kinase binding
0.50	GO:0042802	identical protein binding

0.60	GO:0070436	Grb2-EGFR complex
0.54	GO:0008180	COP9 signalosome
0.53	GO:0005768	endosome
0.51	GO:0005911	cell-cell junction
0.51	GO:0012506	vesicle membrane
0.50	GO:0005730	nucleolus
0.48	GO:0005654	nucleoplasm
0.48	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.41	GO:0005794	Golgi apparatus
0.35	GO:0005829	cytosol

0.49

GO:0004715

sp|Q13591|SEM5A_HUMAN
Semaphorin-5A
Search

SEMA5A

0.88	Semaphorin-F

0.50	GO:0050919	negative chemotaxis
0.49	GO:0048675	axon extension
0.43	GO:1990256	signal clustering
0.41	GO:0048842	positive regulation of axon extension involved in axon guidance
0.41	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis
0.41	GO:0048843	negative regulation of axon extension involved in axon guidance
0.41	GO:0035413	positive regulation of catenin import into nucleus
0.41	GO:2001028	positive regulation of endothelial cell chemotaxis
0.40	GO:2000352	negative regulation of endothelial cell apoptotic process
0.40	GO:0007413	axonal fasciculation

0.51	GO:0038191	neuropilin binding
0.42	GO:0035373	chondroitin sulfate proteoglycan binding
0.41	GO:0045545	syndecan binding
0.41	GO:0030215	semaphorin receptor binding
0.40	GO:0043395	heparan sulfate proteoglycan binding
0.39	GO:0008046	axon guidance receptor activity

0.45	GO:0005615	extracellular space
0.38	GO:1903561	extracellular vesicle
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q13595|TRA2A_HUMAN
Transformer-2 protein homolog alpha
Search

TRA2A

0.97	Transformer-2 protein like protein alpha

0.52	GO:0000398	mRNA splicing, via spliceosome
0.40	GO:0048026	positive regulation of mRNA splicing, via spliceosome
0.38	GO:0021796	cerebral cortex regionalization
0.38	GO:1990403	embryonic brain development
0.38	GO:0048025	negative regulation of mRNA splicing, via spliceosome
0.37	GO:0071333	cellular response to glucose stimulus
0.37	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.36	GO:0051259	protein oligomerization
0.35	GO:0006413	translational initiation

0.59	GO:0003723	RNA binding
0.38	GO:0042802	identical protein binding
0.36	GO:0019904	protein domain specific binding

0.51	GO:0005730	nucleolus
0.37	GO:0005637	nuclear inner membrane
0.36	GO:0005681	spliceosomal complex
0.35	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q13596|SNX1_HUMAN
Sorting nexin-1
Search

SNX1

0.94	Sorting nexin-1

0.78	GO:0042147	retrograde transport, endosome to Golgi
0.68	GO:0006886	intracellular protein transport
0.59	GO:0072673	lamellipodium morphogenesis
0.57	GO:0031623	receptor internalization
0.52	GO:0048193	Golgi vesicle transport
0.46	GO:0016050	vesicle organization
0.38	GO:0045732	positive regulation of protein catabolic process
0.37	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.36	GO:0031175	neuron projection development

0.75	GO:0035091	phosphatidylinositol binding
0.59	GO:1990460	leptin receptor binding
0.57	GO:1990459	transferrin receptor binding
0.56	GO:0005158	insulin receptor binding
0.56	GO:0005154	epidermal growth factor receptor binding
0.53	GO:0045296	cadherin binding
0.50	GO:0042803	protein homodimerization activity
0.50	GO:0046982	protein heterodimerization activity

0.80	GO:0030904	retromer complex
0.66	GO:0005829	cytosol
0.56	GO:0031901	early endosome membrane
0.52	GO:0005764	lysosome
0.45	GO:0019898	extrinsic component of membrane
0.42	GO:0030027	lamellipodium
0.39	GO:0005794	Golgi apparatus
0.37	GO:0043197	dendritic spine
0.37	GO:0014069	postsynaptic density
0.36	GO:0098793	presynapse

sp|Q13601|KRR1_HUMAN
KRR1 small subunit processome component homolog
Search

KRR1

0.71	KRR1 small subunit processome component

0.60	GO:0006364	rRNA processing
0.44	GO:0042274	ribosomal small subunit biogenesis
0.34	GO:0019511	peptidyl-proline hydroxylation
0.32	GO:0055114	oxidation-reduction process

0.58	GO:0003723	RNA binding
0.34	GO:0004656	procollagen-proline 4-dioxygenase activity
0.34	GO:0031418	L-ascorbic acid binding
0.34	GO:0005509	calcium ion binding
0.33	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.33	GO:0005515	protein binding
0.33	GO:0005506	iron ion binding

0.63	GO:0005730	nucleolus
0.54	GO:0045171	intercellular bridge
0.54	GO:0030529	intracellular ribonucleoprotein complex
0.34	GO:0005654	nucleoplasm
0.33	GO:0005737	cytoplasm
0.33	GO:0012505	endomembrane system
0.30	GO:0016020	membrane

0.34	EC:1.14.11.2	GO:0004656
0.34	KEGG:R03219	GO:0004656

sp|Q13606|OR5I1_HUMAN
Olfactory receptor 5I1
Search

0.45	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway

0.75	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.53	GO:0005549	odorant binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q13607|OR2F1_HUMAN
Olfactory receptor 2F1
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.34	GO:0005549	odorant binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q13608|PEX6_HUMAN
Peroxisome assembly factor 2
Search

PEX6

0.89	LOW QUALITY PROTEIN: peroxisome biogenesis factor 6

0.64	GO:0016561	protein import into peroxisome matrix, translocation
0.57	GO:0050821	protein stabilization

0.59	GO:0008022	protein C-terminus binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0032403	protein complex binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0042623	ATPase activity, coupled
0.32	GO:0003677	DNA binding

0.60	GO:0097733	photoreceptor cell cilium
0.55	GO:0005777	peroxisome
0.51	GO:0005829	cytosol
0.40	GO:0031903	microbody membrane
0.39	GO:0044441	ciliary part
0.32	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|Q13609|DNSL3_HUMAN
Deoxyribonuclease gamma
Search

DNASE1L3

0.63	Deoxyribonuclease gamma

0.76	GO:0006308	DNA catabolic process
0.62	GO:0070948	regulation of neutrophil mediated cytotoxicity
0.60	GO:0002283	neutrophil activation involved in immune response
0.59	GO:0002673	regulation of acute inflammatory response
0.57	GO:0030262	apoptotic nuclear changes
0.57	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.56	GO:0010623	programmed cell death involved in cell development
0.37	GO:0002088	lens development in camera-type eye
0.37	GO:0060041	retina development in camera-type eye

0.71	GO:0004536	deoxyribonuclease activity
0.58	GO:0004519	endonuclease activity
0.35	GO:0003779	actin binding
0.35	GO:0003677	DNA binding
0.34	GO:0005509	calcium ion binding

0.48	GO:0005783	endoplasmic reticulum
0.46	GO:0005634	nucleus
0.37	GO:0005576	extracellular region
0.34	GO:0031967	organelle envelope
0.34	GO:0031982	vesicle
0.30	GO:0016020	membrane

sp|Q13610|PWP1_HUMAN
Periodic tryptophan protein 1 homolog
Search

PWP1

0.92	Periodic tryptophan protein 1

0.85	GO:0033140	negative regulation of peptidyl-serine phosphorylation of STAT protein
0.83	GO:2000738	positive regulation of stem cell differentiation
0.83	GO:0034773	histone H4-K20 trimethylation
0.35	GO:0006351	transcription, DNA-templated
0.35	GO:0016573	histone acetylation
0.34	GO:0065009	regulation of molecular function

0.86	GO:1990889	H4K20me3 modified histone binding
0.37	GO:0005246	calcium channel regulator activity
0.35	GO:0004402	histone acetyltransferase activity

0.69	GO:0005730	nucleolus
0.68	GO:0005794	Golgi apparatus

0.35

GO:0004402

sp|Q13613|MTMR1_HUMAN
Myotubularin-related protein 1
Search

MTMR1

0.97	Putative phosphatidylinositol 3-phosphate 3-phosphatase myotubularin mtm1 (Fragment)

0.80	GO:0046856	phosphatidylinositol dephosphorylation
0.74	GO:0035335	peptidyl-tyrosine dephosphorylation

0.85	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity
0.85	GO:0004438	phosphatidylinositol-3-phosphatase activity
0.74	GO:0004725	protein tyrosine phosphatase activity

0.48	GO:0005886	plasma membrane
0.43	GO:0005737	cytoplasm

0.85

GO:0052629

sp|Q13614|MTMR2_HUMAN
Myotubularin-related protein 2
Search

MTMR2

0.97	Myotubularin isoform B

0.75	GO:0035335	peptidyl-tyrosine dephosphorylation
0.70	GO:0031642	negative regulation of myelination
0.69	GO:0060304	regulation of phosphatidylinositol dephosphorylation
0.69	GO:0032288	myelin assembly
0.64	GO:0046856	phosphatidylinositol dephosphorylation
0.63	GO:0051262	protein tetramerization
0.62	GO:0046855	inositol phosphate dephosphorylation
0.61	GO:0048666	neuron development
0.39	GO:2000645	negative regulation of receptor catabolic process
0.38	GO:0097062	dendritic spine maintenance

0.75	GO:0004725	protein tyrosine phosphatase activity
0.68	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity
0.68	GO:0004438	phosphatidylinositol-3-phosphatase activity
0.59	GO:0042803	protein homodimerization activity

0.60	GO:0005774	vacuolar membrane
0.54	GO:0005829	cytosol
0.50	GO:0005634	nucleus
0.38	GO:0043197	dendritic spine
0.37	GO:0014069	postsynaptic density
0.37	GO:0008021	synaptic vesicle
0.37	GO:0070062	extracellular exosome
0.37	GO:0030424	axon
0.37	GO:0097060	synaptic membrane

0.75

GO:0004725

sp|Q13615|MTMR3_HUMAN
Myotubularin-related protein 3
Search

MTMR3

0.70	Myotubularin-related protein 3 isoform c

0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.54	GO:1904562	phosphatidylinositol 5-phosphate metabolic process
0.52	GO:0060304	regulation of phosphatidylinositol dephosphorylation
0.51	GO:2000785	regulation of autophagosome assembly
0.50	GO:0042149	cellular response to glucose starvation
0.48	GO:0046856	phosphatidylinositol dephosphorylation
0.38	GO:0016236	macroautophagy
0.37	GO:0006661	phosphatidylinositol biosynthetic process

0.74	GO:0004725	protein tyrosine phosphatase activity
0.51	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity
0.51	GO:0004438	phosphatidylinositol-3-phosphatase activity
0.49	GO:0019903	protein phosphatase binding
0.49	GO:0046872	metal ion binding
0.47	GO:0004722	protein serine/threonine phosphatase activity

0.46	GO:0019898	extrinsic component of membrane
0.37	GO:0005737	cytoplasm

0.74

GO:0004725

sp|Q13616|CUL1_HUMAN
Cullin-1
Search

CUL1

0.82

Cullin 1

0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.52	GO:0006513	protein monoubiquitination
0.50	GO:0008283	cell proliferation
0.50	GO:0006915	apoptotic process
0.49	GO:0009887	animal organ morphogenesis
0.49	GO:0010498	proteasomal protein catabolic process
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0010265	SCF complex assembly
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway

0.79	GO:0031625	ubiquitin protein ligase binding
0.46	GO:0061630	ubiquitin protein ligase activity

0.74	GO:0031461	cullin-RING ubiquitin ligase complex
0.56	GO:1990452	Parkin-FBXW7-Cul1 ubiquitin ligase complex
0.35	GO:0005654	nucleoplasm
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|Q13617|CUL2_HUMAN
Cullin-2
Search

CUL2

0.92	Testis secretory sperm-binding protein Li 238E

0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.45	GO:0016567	protein ubiquitination
0.45	GO:0001944	vasculature development
0.45	GO:0043009	chordate embryonic development
0.35	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia
0.35	GO:0097193	intrinsic apoptotic signaling pathway
0.35	GO:0007050	cell cycle arrest
0.35	GO:0000082	G1/S transition of mitotic cell cycle
0.35	GO:0043687	post-translational protein modification
0.35	GO:0008285	negative regulation of cell proliferation

0.79	GO:0031625	ubiquitin protein ligase binding
0.46	GO:0061630	ubiquitin protein ligase activity
0.37	GO:0032403	protein complex binding
0.32	GO:0016874	ligase activity

0.74	GO:0031461	cullin-RING ubiquitin ligase complex
0.49	GO:0005654	nucleoplasm
0.42	GO:0005730	nucleolus
0.40	GO:0030891	VCB complex
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.32

GO:0016874

sp|Q13618|CUL3_HUMAN
Cullin-3
Search

CUL3

0.86	Cullin-3-A

0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.57	GO:0044346	fibroblast apoptotic process
0.57	GO:0040016	embryonic cleavage
0.56	GO:0043149	stress fiber assembly
0.56	GO:0072576	liver morphogenesis
0.56	GO:0035024	negative regulation of Rho protein signal transduction
0.55	GO:0045842	positive regulation of mitotic metaphase/anaphase transition
0.55	GO:0017145	stem cell division
0.54	GO:0007080	mitotic metaphase plate congression
0.54	GO:0048208	COPII vesicle coating

0.79	GO:0031625	ubiquitin protein ligase binding
0.56	GO:0031208	POZ domain binding
0.54	GO:0005112	Notch binding
0.52	GO:0030332	cyclin binding
0.50	GO:0004842	ubiquitin-protein transferase activity
0.49	GO:0042803	protein homodimerization activity
0.49	GO:0046982	protein heterodimerization activity
0.45	GO:0061659	ubiquitin-like protein ligase activity

0.75	GO:0031461	cullin-RING ubiquitin ligase complex
0.57	GO:0005827	polar microtubule
0.49	GO:0000139	Golgi membrane
0.44	GO:0005634	nucleus
0.36	GO:0070062	extracellular exosome
0.33	GO:0005829	cytosol
0.33	GO:0070013	intracellular organelle lumen
0.30	GO:0016021	integral component of membrane

0.50

GO:0004842

sp|Q13619|CUL4A_HUMAN
Cullin-4A
Search

0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.58	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle
0.55	GO:0030853	negative regulation of granulocyte differentiation
0.55	GO:2000819	regulation of nucleotide-excision repair
0.54	GO:2000001	regulation of DNA damage checkpoint
0.54	GO:0035019	somatic stem cell population maintenance
0.53	GO:0010498	proteasomal protein catabolic process
0.52	GO:0016567	protein ubiquitination
0.50	GO:0030097	hemopoiesis
0.50	GO:0008284	positive regulation of cell proliferation

0.79	GO:0031625	ubiquitin protein ligase binding
0.46	GO:0061630	ubiquitin protein ligase activity
0.42	GO:0003684	damaged DNA binding

0.77	GO:0031461	cullin-RING ubiquitin ligase complex
0.41	GO:0005654	nucleoplasm
0.41	GO:0005829	cytosol
0.34	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

sp|Q13620|CUL4B_HUMAN
Cullin-4B
Search

CUL4B

0.92	Cullin-4B isoform 2

0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.56	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle
0.55	GO:0035518	histone H2A monoubiquitination
0.54	GO:0070914	UV-damage excision repair
0.51	GO:0045732	positive regulation of protein catabolic process
0.51	GO:0010498	proteasomal protein catabolic process
0.41	GO:0048731	system development
0.41	GO:0009790	embryo development
0.40	GO:0035138	pectoral fin morphogenesis
0.40	GO:0030853	negative regulation of granulocyte differentiation

0.79	GO:0031625	ubiquitin protein ligase binding
0.48	GO:0003684	damaged DNA binding
0.46	GO:0061630	ubiquitin protein ligase activity

0.77	GO:0031461	cullin-RING ubiquitin ligase complex
0.47	GO:0005654	nucleoplasm
0.47	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

sp|Q13621|S12A1_HUMAN
Solute carrier family 12 member 1
Search

SLC12A1

0.96	Solute carrier family 12 member 1, alternative spliced isoform

0.75	GO:1902476	chloride transmembrane transport
0.50	GO:0070634	transepithelial ammonium transport
0.50	GO:0030321	transepithelial chloride transport
0.46	GO:0072488	ammonium transmembrane transport
0.39	GO:0006814	sodium ion transport
0.38	GO:0006813	potassium ion transport
0.38	GO:0006972	hyperosmotic response
0.37	GO:0045795	positive regulation of cell volume
0.36	GO:0032502	developmental process
0.36	GO:0007214	gamma-aminobutyric acid signaling pathway

0.83	GO:0015377	cation:chloride symporter activity
0.46	GO:0008519	ammonium transmembrane transporter activity
0.46	GO:0019901	protein kinase binding
0.35	GO:0004170	dUTP diphosphatase activity

0.53	GO:0070062	extracellular exosome
0.47	GO:0016324	apical plasma membrane
0.34	GO:0016323	basolateral plasma membrane
0.33	GO:0005887	integral component of plasma membrane

0.35	EC:3.6.1.23	GO:0004170
0.35	KEGG:R02100	GO:0004170

sp|Q13625|ASPP2_HUMAN
Apoptosis-stimulating of p53 protein 2
Search

TP53BP2

0.96	Apoptosis-stimulating of p53 protein 2

0.68	GO:1900119	positive regulation of execution phase of apoptosis
0.66	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator
0.42	GO:0009792	embryo development ending in birth or egg hatching
0.40	GO:1901216	positive regulation of neuron death
0.40	GO:0051898	negative regulation of protein kinase B signaling
0.40	GO:0010212	response to ionizing radiation
0.39	GO:0007507	heart development
0.39	GO:0007417	central nervous system development
0.39	GO:1900739	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
0.38	GO:1901030	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

0.68	GO:0051059	NF-kappaB binding
0.65	GO:0002039	p53 binding
0.58	GO:0042802	identical protein binding
0.39	GO:0017124	SH3 domain binding
0.38	GO:0005070	SH3/SH2 adaptor activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0048471	perinuclear region of cytoplasm
0.58	GO:0030054	cell junction
0.55	GO:0005829	cytosol
0.50	GO:0005634	nucleus
0.35	GO:0043233	organelle lumen
0.34	GO:0005739	mitochondrion
0.34	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|Q13627|DYR1A_HUMAN
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
Search

DYRK1A

0.56	Minibrain protein kinase

0.81	GO:0046777	protein autophosphorylation
0.57	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator
0.57	GO:0033120	positive regulation of RNA splicing
0.57	GO:0048025	negative regulation of mRNA splicing, via spliceosome
0.56	GO:0090312	positive regulation of protein deacetylation
0.54	GO:0018107	peptidyl-threonine phosphorylation
0.53	GO:0007623	circadian rhythm
0.53	GO:0018105	peptidyl-serine phosphorylation
0.53	GO:0018108	peptidyl-tyrosine phosphorylation
0.39	GO:0000381	regulation of alternative mRNA splicing, via spliceosome

0.81	GO:0004712	protein serine/threonine/tyrosine kinase activity
0.58	GO:0048156	tau protein binding
0.55	GO:0043621	protein self-association
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.50	GO:0004674	protein serine/threonine kinase activity
0.50	GO:0042802	identical protein binding
0.36	GO:0015631	tubulin binding

0.53	GO:0030425	dendrite
0.52	GO:0030424	axon
0.48	GO:0005856	cytoskeleton
0.45	GO:0005634	nucleus
0.44	GO:0030529	intracellular ribonucleoprotein complex
0.39	GO:0005737	cytoplasm
0.38	GO:0043233	organelle lumen
0.36	GO:0099512	supramolecular fiber
0.36	GO:0044446	intracellular organelle part

0.81

EC:2.7.12.1

GO:0004712

sp|Q13630|FCL_HUMAN
GDP-L-fucose synthase
Search

TSTA3

0.50	GDP-L-fucose synthetase

0.73	GO:0009226	nucleotide-sugar biosynthetic process
0.53	GO:0046368	GDP-L-fucose metabolic process
0.52	GO:0055114	oxidation-reduction process
0.52	GO:0019673	GDP-mannose metabolic process
0.51	GO:0019835	cytolysis
0.35	GO:0007159	leukocyte cell-cell adhesion
0.33	GO:0006091	generation of precursor metabolites and energy

0.60	GO:0050662	coenzyme binding
0.54	GO:0050577	GDP-L-fucose synthase activity
0.49	GO:0042802	identical protein binding
0.36	GO:0042356	GDP-4-dehydro-D-rhamnose reductase activity
0.36	GO:0016853	isomerase activity
0.33	GO:0009055	electron transfer activity
0.32	GO:0003676	nucleic acid binding

0.37	GO:0070062	extracellular exosome
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.54

EC:1.1.1.271

GO:0050577

sp|Q13634|CAD18_HUMAN
Cadherin-18
Search

CDH18

0.92	Cadherin 18, type 2

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.35	GO:0034332	adherens junction organization

0.70

GO:0005509

calcium ion binding

0.55	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q13635|PTC1_HUMAN
Protein patched homolog 1
Search

PTCH1

0.93	LOW QUALITY PROTEIN: protein patched homolog 1

0.60	GO:0021997	neural plate axis specification
0.60	GO:0010157	response to chlorate
0.60	GO:0045879	negative regulation of smoothened signaling pathway
0.60	GO:0007165	signal transduction
0.60	GO:0071397	cellular response to cholesterol
0.59	GO:0009957	epidermal cell fate specification
0.59	GO:0072203	cell proliferation involved in metanephros development
0.59	GO:0010875	positive regulation of cholesterol efflux
0.59	GO:0043616	keratinocyte proliferation
0.58	GO:0040015	negative regulation of multicellular organism growth

0.86	GO:0008158	hedgehog receptor activity
0.60	GO:0005119	smoothened binding
0.60	GO:0097108	hedgehog family protein binding
0.59	GO:0005113	patched binding
0.56	GO:0015485	cholesterol binding
0.55	GO:0030332	cyclin binding
0.55	GO:0008201	heparin binding
0.51	GO:0032403	protein complex binding
0.33	GO:0008270	zinc ion binding

0.56	GO:0005901	caveola
0.55	GO:0030496	midbody
0.54	GO:0048471	perinuclear region of cytoplasm
0.52	GO:0005929	cilium
0.50	GO:0005794	Golgi apparatus
0.42	GO:0044294	dendritic growth cone
0.41	GO:0044295	axonal growth cone
0.40	GO:0014069	postsynaptic density
0.36	GO:0005634	nucleus
0.35	GO:0030666	endocytic vesicle membrane

sp|Q13636|RAB31_HUMAN
Ras-related protein Rab-31
Search

RAB31

0.97	RAB31, member RAS oncogene family

0.56	GO:0043001	Golgi to plasma membrane protein transport
0.54	GO:0090382	phagosome maturation
0.54	GO:0031623	receptor internalization
0.53	GO:0032869	cellular response to insulin stimulus
0.52	GO:0045055	regulated exocytosis
0.49	GO:0097494	regulation of vesicle size
0.46	GO:0007032	endosome organization
0.35	GO:0002283	neutrophil activation involved in immune response
0.35	GO:0002446	neutrophil mediated immunity
0.34	GO:0006662	glycerol ether metabolic process

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0032561	guanyl ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005515	protein binding
0.34	GO:0015035	protein disulfide oxidoreductase activity

0.58	GO:0045335	phagocytic vesicle
0.56	GO:0005769	early endosome
0.56	GO:0032588	trans-Golgi network membrane
0.43	GO:0015629	actin cytoskeleton
0.39	GO:0030666	endocytic vesicle membrane
0.38	GO:0005886	plasma membrane
0.37	GO:0005770	late endosome
0.36	GO:0010008	endosome membrane
0.35	GO:0001726	ruffle
0.35	GO:0070062	extracellular exosome

sp|Q13637|RAB32_HUMAN
Ras-related protein Rab-32
Search

RAB32

0.97	RAB32, member RAS oncogene family

0.76	GO:0032438	melanosome organization
0.74	GO:0035646	endosome to melanosome transport
0.71	GO:0090382	phagosome maturation
0.69	GO:0016192	vesicle-mediated transport
0.63	GO:0019882	antigen processing and presentation
0.63	GO:0007005	mitochondrion organization
0.61	GO:0072657	protein localization to membrane
0.60	GO:0070925	organelle assembly
0.58	GO:0060036	notochord cell vacuolation

0.77	GO:0036461	BLOC-2 complex binding
0.76	GO:0035651	AP-3 adaptor complex binding
0.74	GO:0035650	AP-1 adaptor complex binding
0.73	GO:0030742	GTP-dependent protein binding
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0035612	AP-2 adaptor complex binding

0.79	GO:0005802	trans-Golgi network
0.74	GO:0033162	melanosome membrane
0.69	GO:0044233	ER-mitochondrion membrane contact site
0.69	GO:0045335	phagocytic vesicle
0.66	GO:0005769	early endosome
0.64	GO:0005741	mitochondrial outer membrane
0.59	GO:0005783	endoplasmic reticulum
0.39	GO:0031904	endosome lumen

sp|Q13639|5HT4R_HUMAN
5-hydroxytryptamine receptor 4
Search

HTR4

0.97	5-hydroxytryptamine 4 receptor subunit b

0.85	GO:0032098	regulation of appetite
0.85	GO:0098664	G-protein coupled serotonin receptor signaling pathway
0.78	GO:0098916	anterograde trans-synaptic signaling
0.48	GO:0007214	gamma-aminobutyric acid signaling pathway
0.36	GO:0007187	G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
0.35	GO:0019933	cAMP-mediated signaling
0.35	GO:0050890	cognition

0.85	GO:0004993	G-protein coupled serotonin receptor activity
0.49	GO:0001594	trace-amine receptor activity
0.33	GO:0005515	protein binding

0.67	GO:0005887	integral component of plasma membrane
0.38	GO:0005737	cytoplasm
0.37	GO:0097708	intracellular vesicle
0.37	GO:0012505	endomembrane system

sp|Q13641|TPBG_HUMAN
Trophoblast glycoprotein
Search

TPBG

0.94	Trophoblast glycoprotein like

0.61	GO:0051965	positive regulation of synapse assembly
0.40	GO:2000052	positive regulation of non-canonical Wnt signaling pathway
0.39	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.36	GO:0007155	cell adhesion

0.53	GO:0005783	endoplasmic reticulum
0.38	GO:0009986	cell surface
0.36	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q13642|FHL1_HUMAN
Four and a half LIM domains protein 1
Search

FHL1

0.96	Four and a half LIM domains protein 1

0.57	GO:0003254	regulation of membrane depolarization
0.56	GO:1901016	regulation of potassium ion transmembrane transporter activity
0.56	GO:0043268	positive regulation of potassium ion transport
0.56	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle
0.55	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle
0.55	GO:0030308	negative regulation of cell growth
0.38	GO:0030154	cell differentiation
0.37	GO:0007275	multicellular organism development
0.36	GO:0061061	muscle structure development
0.35	GO:0032957	inositol trisphosphate metabolic process

0.56	GO:0044325	ion channel binding
0.54	GO:0046872	metal ion binding
0.35	GO:0052726	inositol-1,3,4-trisphosphate 5-kinase activity
0.35	GO:0047325	inositol tetrakisphosphate 1-kinase activity
0.35	GO:0052725	inositol-1,3,4-trisphosphate 6-kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.51	GO:0005829	cytosol
0.45	GO:0005634	nucleus
0.44	GO:0005886	plasma membrane
0.38	GO:0005925	focal adhesion

0.35	EC:2.7.1.159	GO:0052726
0.35	KEGG:R03428	GO:0052726

sp|Q13643|FHL3_HUMAN
Four and a half LIM domains protein 3
Search

FHL3

0.96	Four and a half LIM domains protein 3

0.43	GO:0030036	actin cytoskeleton organization
0.41	GO:0055014	atrial cardiac muscle cell development
0.40	GO:0055015	ventricular cardiac muscle cell development
0.40	GO:0060347	heart trabecula formation
0.39	GO:0001649	osteoblast differentiation
0.38	GO:0043066	negative regulation of apoptotic process
0.38	GO:0000122	negative regulation of transcription by RNA polymerase II
0.38	GO:0009725	response to hormone
0.35	GO:0003209	cardiac atrium morphogenesis
0.34	GO:0003208	cardiac ventricle morphogenesis

0.53	GO:0046872	metal ion binding
0.43	GO:0003779	actin binding
0.37	GO:0042802	identical protein binding
0.37	GO:0008134	transcription factor binding
0.34	GO:0003713	transcription coactivator activity

0.47	GO:0030018	Z disc
0.47	GO:0097517	contractile actin filament bundle
0.47	GO:0042641	actomyosin
0.41	GO:0005634	nucleus
0.35	GO:0031430	M band
0.35	GO:0005925	focal adhesion

sp|Q13651|I10R1_HUMAN
Interleukin-10 receptor subunit alpha
Search

IL10RA

0.97	Interleukin-10 receptor subunit alpha

0.50	GO:0019221	cytokine-mediated signaling pathway
0.41	GO:0050807	regulation of synapse organization
0.41	GO:0032496	response to lipopolysaccharide

0.57	GO:0004920	interleukin-10 receptor activity
0.45	GO:0019969	interleukin-10 binding

0.41	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q13670|PM2PB_HUMAN
Putative postmeiotic segregation increased 2-like protein 11
Search

0.86	Putative postmeiotic segregation increased 2-like protein 11

0.66	GO:0006298	mismatch repair
0.52	GO:0016446	somatic hypermutation of immunoglobulin genes
0.47	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.43	GO:0007219	Notch signaling pathway
0.38	GO:0050871	positive regulation of B cell activation
0.37	GO:0048296	regulation of isotype switching to IgA isotypes
0.37	GO:0048302	regulation of isotype switching to IgG isotypes
0.37	GO:0048519	negative regulation of biological process
0.37	GO:0016447	somatic recombination of immunoglobulin gene segments
0.37	GO:0002891	positive regulation of immunoglobulin mediated immune response

0.64	GO:0030983	mismatched DNA binding
0.55	GO:0032407	MutSalpha complex binding
0.51	GO:0003697	single-stranded DNA binding
0.49	GO:0032559	adenyl ribonucleotide binding
0.49	GO:0004519	endonuclease activity
0.48	GO:0008144	drug binding
0.48	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0008270	zinc ion binding
0.41	GO:0016887	ATPase activity
0.39	GO:0003684	damaged DNA binding

0.51	GO:0032389	MutLalpha complex
0.49	GO:0036464	cytoplasmic ribonucleoprotein granule
0.48	GO:0005654	nucleoplasm
0.46	GO:0015630	microtubule cytoskeleton
0.45	GO:0005829	cytosol
0.42	GO:0031965	nuclear membrane
0.41	GO:0005886	plasma membrane
0.35	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.41

GO:0016887

sp|Q13671|RIN1_HUMAN
Ras and Rab interactor 1
Search

RIN1

0.97	Ras interaction/interference protein 1

0.60	GO:0007165	signal transduction
0.42	GO:0031914	negative regulation of synaptic plasticity
0.41	GO:0043547	positive regulation of GTPase activity
0.40	GO:0008306	associative learning
0.40	GO:0007613	memory
0.40	GO:0006897	endocytosis

0.41	GO:0005096	GTPase activator activity
0.41	GO:0017016	Ras GTPase binding
0.37	GO:0005085	guanyl-nucleotide exchange factor activity
0.36	GO:0005509	calcium ion binding

0.46	GO:0005886	plasma membrane
0.43	GO:0005856	cytoskeleton
0.42	GO:0005737	cytoplasm
0.40	GO:0043025	neuronal cell body
0.40	GO:0030425	dendrite
0.30	GO:0016021	integral component of membrane

sp|Q13683|ITA7_HUMAN
Integrin alpha-7
Search

ITGA7

0.96	Integrin alpha-7 Integrin alpha-7 heavy chain Integrin alpha-7 light chain

0.77	GO:0007229	integrin-mediated signaling pathway
0.70	GO:0007155	cell adhesion
0.57	GO:0035987	endodermal cell differentiation
0.43	GO:0010668	ectodermal cell differentiation
0.43	GO:0035878	nail development
0.43	GO:0046847	filopodium assembly
0.42	GO:0097186	amelogenesis
0.42	GO:0016477	cell migration
0.42	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway
0.42	GO:0050873	brown fat cell differentiation

0.44	GO:0038132	neuregulin binding
0.43	GO:0031994	insulin-like growth factor I binding
0.43	GO:0005178	integrin binding
0.41	GO:0045296	cadherin binding
0.39	GO:0043236	laminin binding
0.35	GO:0046872	metal ion binding
0.34	GO:0046982	protein heterodimerization activity

0.78	GO:0008305	integrin complex
0.43	GO:0030055	cell-substrate junction
0.42	GO:0009925	basal plasma membrane
0.42	GO:0009986	cell surface
0.41	GO:0005604	basement membrane
0.40	GO:0098552	side of membrane
0.38	GO:0005912	adherens junction
0.38	GO:0031594	neuromuscular junction
0.38	GO:0042383	sarcolemma
0.34	GO:0030175	filopodium

sp|Q13685|AAMP_HUMAN
Angio-associated migratory cell protein
Search

AAMP

0.92	Angio-associated migratory protein (Predicted)

0.61	GO:0042273	ribosomal large subunit biogenesis
0.54	GO:0014909	smooth muscle cell migration
0.48	GO:0010595	positive regulation of endothelial cell migration
0.47	GO:0001525	angiogenesis
0.44	GO:0030154	cell differentiation
0.39	GO:0045766	positive regulation of angiogenesis

0.57	GO:0051082	unfolded protein binding
0.53	GO:0008201	heparin binding

0.81	GO:0045171	intercellular bridge
0.68	GO:0015630	microtubule cytoskeleton
0.65	GO:0005829	cytosol
0.63	GO:0030687	preribosome, large subunit precursor
0.54	GO:0009986	cell surface
0.39	GO:0005886	plasma membrane

sp|Q13686|ALKB1_HUMAN
Nucleic acid dioxygenase ALKBH1
Search

ALKBH1

0.60	Alpha-ketoglutarate-dependent dioxygenase alkB

0.65	GO:1990983	tRNA demethylation
0.65	GO:0006281	DNA repair
0.60	GO:0070129	regulation of mitochondrial translation
0.60	GO:0080111	DNA demethylation
0.60	GO:0050918	positive chemotaxis
0.59	GO:0002101	tRNA wobble cytosine modification
0.59	GO:0042245	RNA repair
0.58	GO:0043524	negative regulation of neuron apoptotic process
0.58	GO:0001764	neuron migration
0.56	GO:0006448	regulation of translational elongation

0.66	GO:1990984	tRNA demethylase activity
0.65	GO:0070579	methylcytosine dioxygenase activity
0.61	GO:0042056	chemoattractant activity
0.57	GO:0008198	ferrous iron binding
0.55	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity
0.51	GO:0043734	DNA-N1-methyladenine dioxygenase activity
0.51	GO:0000049	tRNA binding
0.39	GO:0103053	1-ethyladenine demethylase activity
0.35	GO:0008168	methyltransferase activity
0.32	GO:0005524	ATP binding

0.60	GO:0005719	nuclear euchromatin
0.47	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.55

EC:4.2.99.18

GO:0003906

sp|Q13698|CAC1S_HUMAN
Voltage-dependent L-type calcium channel subunit alpha-1S
Search

CACNA1S

0.73	Voltage-dependent L-type calcium channel subunit alpha

0.77	GO:0034765	regulation of ion transmembrane transport
0.77	GO:0070588	calcium ion transmembrane transport
0.56	GO:0006936	muscle contraction
0.50	GO:0086010	membrane depolarization during action potential
0.43	GO:0071313	cellular response to caffeine
0.39	GO:0002074	extraocular skeletal muscle development
0.39	GO:0043501	skeletal muscle adaptation
0.38	GO:0007520	myoblast fusion
0.38	GO:0048741	skeletal muscle fiber development
0.38	GO:0070509	calcium ion import

0.82	GO:0005245	voltage-gated calcium channel activity
0.51	GO:0005509	calcium ion binding
0.40	GO:0005516	calmodulin binding
0.36	GO:0044325	ion channel binding
0.35	GO:0030506	ankyrin binding
0.35	GO:0051393	alpha-actinin binding
0.33	GO:0016798	hydrolase activity, acting on glycosyl bonds

0.81	GO:0005891	voltage-gated calcium channel complex
0.59	GO:0030315	T-tubule
0.56	GO:0031674	I band
0.38	GO:0016529	sarcoplasmic reticulum
0.34	GO:0005887	integral component of plasma membrane

0.33

EC:3.2

GO:0016798

sp|Q13702|RAPSN_HUMAN
43 kDa receptor-associated protein of the synapse
Search

RAPSN

0.97	Receptor-associated protein of the synapse

0.75	GO:0007268	chemical synaptic transmission
0.61	GO:0043525	positive regulation of neuron apoptotic process
0.44	GO:1900075	positive regulation of neuromuscular synaptic transmission
0.43	GO:1901626	regulation of postsynaptic membrane organization
0.43	GO:0071340	skeletal muscle acetylcholine-gated channel clustering
0.38	GO:0007416	synapse assembly

0.85	GO:0033130	acetylcholine receptor binding
0.84	GO:0043495	protein membrane anchor
0.42	GO:0035255	ionotropic glutamate receptor binding
0.35	GO:0046872	metal ion binding

0.73	GO:0045202	synapse
0.57	GO:0005813	centrosome
0.56	GO:0098590	plasma membrane region
0.52	GO:0005794	Golgi apparatus
0.51	GO:0005829	cytosol
0.39	GO:0030054	cell junction

sp|Q13705|AVR2B_HUMAN
Activin receptor type-2B
Search

ACVR2B

0.74	Serine/threonine-protein kinase receptor

0.79	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
0.66	GO:0023014	signal transduction by protein phosphorylation
0.54	GO:0032927	positive regulation of activin receptor signaling pathway
0.54	GO:0060836	lymphatic endothelial cell differentiation
0.54	GO:0048617	embryonic foregut morphogenesis
0.53	GO:0061298	retina vasculature development in camera-type eye
0.53	GO:0060841	venous blood vessel development
0.53	GO:0001946	lymphangiogenesis
0.52	GO:0030501	positive regulation of bone mineralization
0.52	GO:0001974	blood vessel remodeling

0.81	GO:0004675	transmembrane receptor protein serine/threonine kinase activity
0.79	GO:0004702	signal transducer, downstream of receptor, with serine/threonine kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.54	GO:0048185	activin binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0046872	metal ion binding
0.51	GO:0019838	growth factor binding
0.50	GO:0004712	protein serine/threonine/tyrosine kinase activity

0.49	GO:0043235	receptor complex
0.42	GO:0043234	protein complex
0.38	GO:0005737	cytoplasm
0.36	GO:0045178	basal part of cell
0.34	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.81

GO:0004675

sp|Q13724|MOGS_HUMAN
Mannosyl-oligosaccharide glucosidase
Search

MOGS

0.85	Mannosyl-oligosaccharide glucosidase

0.72	GO:0009311	oligosaccharide metabolic process
0.36	GO:0006487	protein N-linked glycosylation
0.34	GO:0006457	protein folding

0.83	GO:0004573	mannosyl-oligosaccharide glucosidase activity
0.32	GO:0016757	transferase activity, transferring glycosyl groups

0.50	GO:0005783	endoplasmic reticulum
0.38	GO:0070062	extracellular exosome
0.38	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.37	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.83

EC:3.2.1.106

GO:0004573

sp|Q13733|AT1A4_HUMAN
Sodium/potassium-transporting ATPase subunit alpha-4
Search

0.64	Sodium/potassium-transporting ATPase subunit alpha

0.84	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient
0.75	GO:0090662	ATP hydrolysis coupled transmembrane transport
0.72	GO:0006814	sodium ion transport
0.71	GO:0006813	potassium ion transport
0.58	GO:0030004	cellular monovalent inorganic cation homeostasis
0.55	GO:0055078	sodium ion homeostasis
0.54	GO:0008542	visual learning
0.54	GO:0007626	locomotory behavior
0.53	GO:0008015	blood circulation
0.53	GO:0140115	export across plasma membrane

0.84	GO:0005391	sodium:potassium-exchanging ATPase activity
0.54	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.53	GO:0046872	metal ion binding
0.49	GO:0051087	chaperone binding
0.48	GO:1990239	steroid hormone binding
0.47	GO:0001540	amyloid-beta binding
0.43	GO:1901681	sulfur compound binding

0.54	GO:0005890	sodium:potassium-exchanging ATPase complex
0.53	GO:0042383	sarcolemma
0.52	GO:0043209	myelin sheath
0.47	GO:0036477	somatodendritic compartment
0.46	GO:0043005	neuron projection
0.46	GO:0044297	cell body
0.43	GO:0005794	Golgi apparatus
0.43	GO:0005783	endoplasmic reticulum
0.40	GO:0005634	nucleus
0.40	GO:0045202	synapse

0.84

EC:3.6.3.9

GO:0005391

sp|Q13740|CD166_HUMAN
CD166 antigen
Search

ALCAM

0.97	Activated leukocyte cell adhesion molecule

0.65	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.61	GO:0008045	motor neuron axon guidance

0.57

GO:0042802

identical protein binding

0.66	GO:0042101	T cell receptor complex
0.65	GO:0001772	immunological synapse
0.59	GO:0009897	external side of plasma membrane
0.58	GO:0043025	neuronal cell body
0.58	GO:0030424	axon
0.53	GO:0031226	intrinsic component of plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q13748|TBA3C_HUMAN
Tubulin alpha-3C/D chain
Search

0.53	Tubulin alpha chain, testis-specific

0.71	GO:0007017	microtubule-based process
0.70	GO:0007010	cytoskeleton organization
0.36	GO:0033198	response to ATP
0.36	GO:0035590	purinergic nucleotide receptor signaling pathway
0.35	GO:0060079	excitatory postsynaptic potential
0.34	GO:0098655	cation transmembrane transport

0.76	GO:0005200	structural constituent of cytoskeleton
0.67	GO:0003924	GTPase activity
0.65	GO:0005525	GTP binding
0.36	GO:0004931	extracellularly ATP-gated cation channel activity
0.36	GO:0016502	nucleotide receptor activity
0.36	GO:0035586	purinergic receptor activity
0.33	GO:0005515	protein binding
0.32	GO:0003677	DNA binding

0.72	GO:0005874	microtubule
0.47	GO:0005737	cytoplasm
0.40	GO:0036064	ciliary basal body
0.35	GO:0098794	postsynapse
0.34	GO:0005887	integral component of plasma membrane
0.34	GO:0005634	nucleus

sp|Q13751|LAMB3_HUMAN
Laminin subunit beta-3
Search

LAMB3

0.93	Laminin subunit beta 3

0.85	GO:0035987	endodermal cell differentiation
0.67	GO:0050873	brown fat cell differentiation
0.61	GO:0021812	neuronal-glial interaction involved in cerebral cortex radial glia guided migration
0.58	GO:0034446	substrate adhesion-dependent cell spreading
0.55	GO:0030335	positive regulation of cell migration
0.54	GO:0042476	odontogenesis
0.53	GO:0031175	neuron projection development
0.41	GO:0007162	negative regulation of cell adhesion
0.41	GO:0007566	embryo implantation
0.37	GO:0007611	learning or memory

0.55	GO:0005201	extracellular matrix structural constituent
0.41	GO:0043208	glycosphingolipid binding
0.40	GO:0032403	protein complex binding
0.39	GO:0050839	cell adhesion molecule binding
0.38	GO:0005102	receptor binding
0.38	GO:0019899	enzyme binding
0.35	GO:0003777	microtubule motor activity
0.34	GO:0016887	ATPase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding

0.80	GO:0043256	laminin complex
0.51	GO:0005615	extracellular space
0.40	GO:0048471	perinuclear region of cytoplasm
0.37	GO:1903561	extracellular vesicle
0.36	GO:0030286	dynein complex
0.36	GO:0005634	nucleus

0.34

GO:0016887

sp|Q13753|LAMC2_HUMAN
Laminin subunit gamma-2
Search

LAMC2

0.87	Laminin subunit gamma 2

0.86	GO:0070831	basement membrane assembly
0.71	GO:0048731	system development
0.59	GO:0030335	positive regulation of cell migration
0.58	GO:0008284	positive regulation of cell proliferation
0.46	GO:0034446	substrate adhesion-dependent cell spreading
0.43	GO:0033627	cell adhesion mediated by integrin
0.41	GO:0035239	tube morphogenesis
0.40	GO:0031581	hemidesmosome assembly
0.40	GO:0022617	extracellular matrix disassembly
0.38	GO:0016477	cell migration

0.43	GO:0008201	heparin binding
0.39	GO:0005201	extracellular matrix structural constituent
0.35	GO:0005515	protein binding

0.82	GO:0005604	basement membrane
0.40	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0005938	cell cortex
0.39	GO:0005615	extracellular space
0.37	GO:0043234	protein complex
0.30	GO:0016020	membrane

sp|Q13761|RUNX3_HUMAN
Runt-related transcription factor 3
Search

RUNX3

0.89	Runt-related transcription factor

0.69	GO:0045893	positive regulation of transcription, DNA-templated
0.55	GO:0006351	transcription, DNA-templated
0.54	GO:0071559	response to transforming growth factor beta
0.54	GO:0051216	cartilage development
0.50	GO:0030097	hemopoiesis
0.48	GO:0001503	ossification
0.47	GO:0030154	cell differentiation
0.46	GO:0045595	regulation of cell differentiation
0.46	GO:0007399	nervous system development
0.46	GO:0006468	protein phosphorylation

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0030554	adenyl nucleotide binding
0.55	GO:0003677	DNA binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.42	GO:0001067	regulatory region nucleic acid binding
0.40	GO:0042809	vitamin D receptor binding
0.38	GO:0043425	bHLH transcription factor binding
0.38	GO:0070491	repressing transcription factor binding

0.61	GO:0005634	nucleus
0.48	GO:0070013	intracellular organelle lumen
0.48	GO:0005829	cytosol
0.44	GO:0043232	intracellular non-membrane-bounded organelle
0.44	GO:0044446	intracellular organelle part
0.36	GO:0005667	transcription factor complex

sp|Q13769|THOC5_HUMAN
THO complex subunit 5 homolog
Search

THOC5

0.94	THO complex subunit 5

0.83	GO:0046784	viral mRNA export from host cell nucleus
0.83	GO:2000002	negative regulation of DNA damage checkpoint
0.83	GO:0030224	monocyte differentiation
0.78	GO:0032786	positive regulation of DNA-templated transcription, elongation
0.78	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.75	GO:0051028	mRNA transport
0.73	GO:0006405	RNA export from nucleus
0.53	GO:0010467	gene expression
0.50	GO:0060215	primitive hemopoiesis
0.48	GO:0016071	mRNA metabolic process

0.58	GO:0003729	mRNA binding
0.38	GO:0005515	protein binding

0.83	GO:0000445	THO complex part of transcription export complex
0.74	GO:0000784	nuclear chromosome, telomeric region
0.66	GO:0005654	nucleoplasm
0.39	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q13772|NCOA4_HUMAN
Nuclear receptor coactivator 4
Search

NCOA4

0.96	Nuclear receptor coactivator 4

0.85	GO:0006622	protein targeting to lysosome
0.69	GO:0006879	cellular iron ion homeostasis
0.46	GO:0009725	response to hormone
0.43	GO:0008584	male gonad development
0.41	GO:0030522	intracellular receptor signaling pathway
0.41	GO:0071396	cellular response to lipid
0.41	GO:0071407	cellular response to organic cyclic compound
0.40	GO:0071495	cellular response to endogenous stimulus
0.40	GO:0045893	positive regulation of transcription, DNA-templated
0.37	GO:0006351	transcription, DNA-templated

0.44	GO:0050681	androgen receptor binding
0.41	GO:0003713	transcription coactivator activity
0.40	GO:0004649	poly(ADP-ribose) glycohydrolase activity
0.37	GO:0004872	receptor activity
0.36	GO:0004252	serine-type endopeptidase activity
0.32	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.32	GO:0005524	ATP binding

0.85	GO:0044754	autolysosome
0.56	GO:0005739	mitochondrion
0.38	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.40

EC:3.2.1.143

GO:0004649

sp|Q13790|APOF_HUMAN
Apolipoprotein F
Search

APOF

0.97	LOW QUALITY PROTEIN: apolipoprotein F

0.51	GO:0008203	cholesterol metabolic process
0.47	GO:0006869	lipid transport
0.45	GO:0006641	triglyceride metabolic process
0.44	GO:0015850	organic hydroxy compound transport

0.45	GO:0015485	cholesterol binding
0.43	GO:0005319	lipid transporter activity
0.42	GO:0005102	receptor binding

0.73	GO:0005615	extracellular space
0.52	GO:1990777	lipoprotein particle
0.30	GO:0044425	membrane part

sp|Q13794|APR_HUMAN
Phorbol-12-myristate-13-acetate-induced protein 1
Search

PMAIP1

0.97	Phorbol-12-myristate-13-acetate-induced protein 1

0.86	GO:0001836	release of cytochrome c from mitochondria
0.85	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.68	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator
0.67	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
0.66	GO:0032461	positive regulation of protein oligomerization
0.66	GO:0090200	positive regulation of release of cytochrome c from mitochondria
0.66	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator
0.66	GO:0046902	regulation of mitochondrial membrane permeability
0.65	GO:0010907	positive regulation of glucose metabolic process
0.65	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway

0.39

GO:0005515

protein binding

0.54	GO:0005829	cytosol
0.51	GO:0005739	mitochondrion
0.49	GO:0005634	nucleus
0.41	GO:0031968	organelle outer membrane

sp|Q13795|ARFRP_HUMAN
ADP-ribosylation factor-related protein 1
Search

ARFRP1

0.95	ADP ribosylation factor related protein 1

0.54	GO:0043001	Golgi to plasma membrane protein transport
0.54	GO:0034067	protein localization to Golgi apparatus
0.53	GO:0007369	gastrulation
0.52	GO:0042147	retrograde transport, endosome to Golgi
0.33	GO:0009607	response to biotic stimulus
0.33	GO:0007165	signal transduction
0.33	GO:0006886	intracellular protein transport

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0003924	GTPase activity
0.33	GO:0005515	protein binding

0.52	GO:0005802	trans-Golgi network
0.47	GO:0005829	cytosol
0.34	GO:0000139	Golgi membrane
0.33	GO:0030117	membrane coat
0.30	GO:0031224	intrinsic component of membrane

sp|Q13796|SHRM2_HUMAN
Protein Shroom2
Search

SHROOM2

0.93	Shroom family member 2

0.86	GO:0045176	apical protein localization
0.85	GO:0032401	establishment of melanosome localization

0.78

GO:0051015

actin filament binding

0.66

GO:0030864

cortical actin cytoskeleton

sp|Q13797|ITA9_HUMAN
Integrin alpha-9
Search

ITGA9

0.96	Integrin subunit alpha 9

0.78	GO:0007229	integrin-mediated signaling pathway
0.70	GO:0007155	cell adhesion
0.56	GO:0030593	neutrophil chemotaxis
0.40	GO:0042060	wound healing
0.37	GO:0000902	cell morphogenesis
0.37	GO:0046852	positive regulation of bone remodeling
0.37	GO:0045672	positive regulation of osteoclast differentiation
0.37	GO:0045124	regulation of bone resorption
0.37	GO:0090074	negative regulation of protein homodimerization activity
0.36	GO:0045123	cellular extravasation

0.41	GO:0043236	laminin binding
0.41	GO:0005518	collagen binding
0.37	GO:0019960	C-X3-C chemokine binding
0.35	GO:0050839	cell adhesion molecule binding
0.34	GO:0046872	metal ion binding

0.78	GO:0008305	integrin complex
0.57	GO:0009925	basal plasma membrane
0.37	GO:0071133	alpha9-beta1 integrin-ADAM8 complex
0.35	GO:0009986	cell surface

sp|Q13813|SPTN1_HUMAN
Spectrin alpha chain, non-erythrocytic 1
Search

SPTAN1

0.96	Spectrin alpha chain, non-erythrocytic 1

0.42	GO:0051693	actin filament capping
0.39	GO:0007010	cytoskeleton organization
0.38	GO:0043312	neutrophil degranulation
0.37	GO:0046907	intracellular transport
0.37	GO:0007411	axon guidance
0.37	GO:0000165	MAPK cascade
0.37	GO:0071166	ribonucleoprotein complex localization
0.36	GO:0051028	mRNA transport
0.36	GO:0048193	Golgi vesicle transport
0.36	GO:0006405	RNA export from nucleus

0.70	GO:0005509	calcium ion binding
0.57	GO:0045296	cadherin binding
0.42	GO:0003779	actin binding
0.41	GO:0005516	calmodulin binding
0.41	GO:0030507	spectrin binding
0.39	GO:0005200	structural constituent of cytoskeleton
0.38	GO:0046982	protein heterodimerization activity
0.38	GO:0047485	protein N-terminus binding
0.37	GO:0019905	syntaxin binding
0.37	GO:0005088	Ras guanyl-nucleotide exchange factor activity

0.52	GO:0015630	microtubule cytoskeleton
0.45	GO:0043227	membrane-bounded organelle
0.43	GO:0030864	cortical actin cytoskeleton
0.41	GO:0005916	fascia adherens
0.41	GO:0033270	paranode region of axon
0.41	GO:0016328	lateral plasma membrane
0.40	GO:0030018	Z disc
0.40	GO:0043209	myelin sheath
0.40	GO:0043230	extracellular organelle
0.38	GO:0005615	extracellular space

sp|Q13822|ENPP2_HUMAN
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2
Search

ENPP2

0.94	Ectonucleotide pyrophosphatase/phosphodiesterase 2

0.81	GO:0045765	regulation of angiogenesis
0.78	GO:0030334	regulation of cell migration
0.73	GO:0006955	immune response
0.71	GO:0006898	receptor-mediated endocytosis
0.71	GO:0006935	chemotaxis
0.64	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.55	GO:0034638	phosphatidylcholine catabolic process
0.55	GO:2000394	positive regulation of lamellipodium morphogenesis
0.51	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
0.50	GO:2000147	positive regulation of cell motility

0.86	GO:0004528	phosphodiesterase I activity
0.82	GO:0004622	lysophospholipase activity
0.80	GO:0004551	nucleotide diphosphatase activity
0.80	GO:0005044	scavenger receptor activity
0.77	GO:0001871	pattern binding
0.69	GO:0030246	carbohydrate binding
0.53	GO:0046872	metal ion binding
0.50	GO:0003676	nucleic acid binding
0.50	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity
0.35	GO:0008134	transcription factor binding

0.47	GO:0005615	extracellular space
0.36	GO:0005887	integral component of plasma membrane
0.34	GO:0005794	Golgi apparatus

0.86

EC:3.1.4.1

GO:0004528

sp|Q13823|NOG2_HUMAN
Nucleolar GTP-binding protein 2
Search

GNL2

0.74	Nucleolar GTP-binding protein 2

0.48	GO:0000448	cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.47	GO:0003407	neural retina development
0.46	GO:0007096	regulation of exit from mitosis
0.45	GO:0045664	regulation of neuron differentiation

0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0003924	GTPase activity
0.34	GO:0003723	RNA binding

0.73	GO:0005730	nucleolus
0.30	GO:0016020	membrane

sp|Q13825|AUHM_HUMAN
Methylglutaconyl-CoA hydratase, mitochondrial
Search

AUH

0.55	AU RNA binding methylglutaconyl-CoA hydratase

0.45	GO:0006635	fatty acid beta-oxidation
0.39	GO:0006552	leucine catabolic process
0.35	GO:0007623	circadian rhythm
0.35	GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
0.33	GO:0042357	thiamine diphosphate metabolic process
0.33	GO:0042723	thiamine-containing compound metabolic process
0.33	GO:0018130	heterocycle biosynthetic process
0.33	GO:1901362	organic cyclic compound biosynthetic process
0.33	GO:0019438	aromatic compound biosynthetic process
0.33	GO:0044272	sulfur compound biosynthetic process

0.53	GO:0003730	mRNA 3'-UTR binding
0.52	GO:0004300	enoyl-CoA hydratase activity
0.41	GO:0050011	itaconyl-CoA hydratase activity
0.40	GO:0004490	methylglutaconyl-CoA hydratase activity
0.34	GO:0004788	thiamine diphosphokinase activity
0.34	GO:0030975	thiamine binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003700	DNA binding transcription factor activity
0.31	GO:0016787	hydrolase activity

0.40	GO:0005739	mitochondrion
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0005634	nucleus
0.33	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.52	EC:4.2.1.17	GO:0004300
0.40	KEGG:R02085	GO:0004490

sp|Q13829|BACD2_HUMAN
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2
Search

TNFAIP1

0.97	BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2

0.74	GO:0051260	protein homooligomerization
0.49	GO:0043149	stress fiber assembly
0.49	GO:0035024	negative regulation of Rho protein signal transduction
0.46	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.45	GO:0016477	cell migration
0.44	GO:0016567	protein ubiquitination
0.44	GO:0006955	immune response
0.40	GO:0045740	positive regulation of DNA replication
0.39	GO:0006260	DNA replication
0.36	GO:0051291	protein heterooligomerization

0.48	GO:0017049	GTP-Rho binding
0.45	GO:0004842	ubiquitin-protein transferase activity
0.38	GO:0019904	protein domain specific binding
0.37	GO:0005112	Notch binding
0.33	GO:0004672	protein kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.48	GO:0031463	Cul3-RING ubiquitin ligase complex
0.45	GO:0005768	endosome
0.42	GO:0005730	nucleolus
0.35	GO:0036038	MKS complex
0.35	GO:0005654	nucleoplasm
0.35	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.45

GO:0004842

sp|Q13835|PKP1_HUMAN
Plakophilin-1
Search

PKP1

0.97	Plakophilin-1

0.77	GO:0098609	cell-cell adhesion
0.63	GO:0045110	intermediate filament bundle assembly
0.58	GO:1902373	negative regulation of mRNA catabolic process
0.43	GO:0002934	desmosome organization
0.43	GO:0048496	maintenance of animal organ identity
0.43	GO:0086069	bundle of His cell to Purkinje myocyte communication
0.43	GO:0098911	regulation of ventricular cardiac muscle cell action potential
0.43	GO:0086005	ventricular cardiac muscle cell action potential
0.42	GO:0086019	cell-cell signaling involved in cardiac conduction
0.42	GO:0086091	regulation of heart rate by cardiac conduction

0.59	GO:0005521	lamin binding
0.44	GO:0019215	intermediate filament binding
0.43	GO:0045294	alpha-catenin binding
0.42	GO:0005080	protein kinase C binding
0.41	GO:0045296	cadherin binding
0.41	GO:0032947	protein complex scaffold activity
0.38	GO:0030280	structural constituent of epidermis
0.34	GO:0004871	signal transducer activity
0.33	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication
0.33	GO:0017080	sodium channel regulator activity

0.82	GO:0030057	desmosome
0.60	GO:1990124	messenger ribonucleoprotein complex
0.59	GO:0005634	nucleus
0.50	GO:0043233	organelle lumen
0.45	GO:0044446	intracellular organelle part
0.44	GO:0005886	plasma membrane
0.42	GO:0014704	intercalated disc
0.40	GO:0045111	intermediate filament cytoskeleton
0.39	GO:0005912	adherens junction
0.39	GO:0099512	supramolecular fiber

0.31

GO:0016787

sp|Q13838|DX39B_HUMAN
Spliceosome RNA helicase DDX39B
Search

DDX39B

0.86	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B

0.78	GO:0046784	viral mRNA export from host cell nucleus
0.77	GO:2000002	negative regulation of DNA damage checkpoint
0.73	GO:0010501	RNA secondary structure unwinding
0.71	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.70	GO:0000245	spliceosomal complex assembly
0.69	GO:0032786	positive regulation of DNA-templated transcription, elongation
0.68	GO:0051028	mRNA transport
0.67	GO:0006405	RNA export from nucleus
0.43	GO:0006974	cellular response to DNA damage stimulus

0.78	GO:0043008	ATP-dependent protein binding
0.76	GO:0030621	U4 snRNA binding
0.73	GO:0017070	U6 snRNA binding
0.69	GO:0004004	ATP-dependent RNA helicase activity
0.64	GO:0042802	identical protein binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.75	GO:0005687	U4 snRNP
0.72	GO:0000346	transcription export complex
0.71	GO:0005688	U6 snRNP
0.69	GO:0016607	nuclear speck
0.68	GO:0005681	spliceosomal complex
0.46	GO:0005730	nucleolus
0.45	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q13867|BLMH_HUMAN
Bleomycin hydrolase
Search

BLMH

0.76	Bleomycin hydrolase

0.60	GO:0006508	proteolysis
0.49	GO:0043418	homocysteine catabolic process
0.49	GO:0042493	response to drug
0.49	GO:0009636	response to toxic substance
0.35	GO:0000209	protein polyubiquitination
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process

0.74	GO:0004197	cysteine-type endopeptidase activity
0.51	GO:0042802	identical protein binding
0.38	GO:0004177	aminopeptidase activity
0.34	GO:0004180	carboxypeptidase activity
0.33	GO:0003735	structural constituent of ribosome

0.37	GO:0070062	extracellular exosome
0.36	GO:0005737	cytoplasm
0.34	GO:0005634	nucleus
0.32	GO:0030529	intracellular ribonucleoprotein complex
0.32	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

0.74

EC:3.4.22

GO:0004197

sp|Q13868|EXOS2_HUMAN
Exosome complex component RRP4
Search

EXOSC2

0.74	Exosome component 2

0.55	GO:0030307	positive regulation of cell growth
0.49	GO:0071049	nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription
0.49	GO:0071034	CUT catabolic process
0.49	GO:0071051	polyadenylation-dependent snoRNA 3'-end processing
0.49	GO:0034475	U4 snRNA 3'-end processing
0.49	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
0.48	GO:0071038	nuclear polyadenylation-dependent tRNA catabolic process
0.48	GO:0000467	exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.48	GO:0071035	nuclear polyadenylation-dependent rRNA catabolic process
0.48	GO:0034427	nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'

0.59	GO:0003723	RNA binding
0.43	GO:0004527	exonuclease activity
0.37	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.35	GO:0004540	ribonuclease activity
0.34	GO:0005515	protein binding
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.79	GO:0000178	exosome (RNase complex)
0.51	GO:0005730	nucleolus
0.39	GO:0005737	cytoplasm
0.34	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.34	GO:0005654	nucleoplasm

0.37

GO:0004715

sp|Q13873|BMPR2_HUMAN
Bone morphogenetic protein receptor type-2
Search

BMPR2

0.62	Receptor protein serine/threonine kinase

0.79	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
0.71	GO:0061036	positive regulation of cartilage development
0.70	GO:0060350	endochondral bone morphogenesis
0.69	GO:0030166	proteoglycan biosynthetic process
0.65	GO:0023014	signal transduction by protein phosphorylation
0.61	GO:0003252	negative regulation of cell proliferation involved in heart valve morphogenesis
0.61	GO:0014916	regulation of lung blood pressure
0.61	GO:1902731	negative regulation of chondrocyte proliferation
0.60	GO:0072577	endothelial cell apoptotic process
0.60	GO:0003186	tricuspid valve morphogenesis

0.79	GO:0004675	transmembrane receptor protein serine/threonine kinase activity
0.78	GO:0004702	signal transducer, downstream of receptor, with serine/threonine kinase activity
0.59	GO:0036122	BMP binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0019838	growth factor binding
0.35	GO:0046872	metal ion binding

0.56	GO:0005901	caveola
0.56	GO:0005913	cell-cell adherens junction
0.55	GO:0014069	postsynaptic density
0.52	GO:0009986	cell surface
0.49	GO:0005654	nucleoplasm
0.48	GO:0005887	integral component of plasma membrane
0.36	GO:0009925	basal plasma membrane
0.35	GO:0016324	apical plasma membrane
0.35	GO:0043025	neuronal cell body
0.35	GO:0043235	receptor complex

0.79

GO:0004675

sp|Q13875|MOBP_HUMAN
Myelin-associated oligodendrocyte basic protein
Search

MOBP

0.97	Myelin-associated oligodendrocyte basic protein isoform 2

0.72	GO:0030050	vesicle transport along actin filament
0.50	GO:0007399	nervous system development

0.86	GO:0019911	structural constituent of myelin sheath
0.68	GO:0017022	myosin binding
0.65	GO:0017137	Rab GTPase binding
0.60	GO:0003779	actin binding

0.82	GO:0043209	myelin sheath
0.66	GO:0030864	cortical actin cytoskeleton
0.60	GO:0005739	mitochondrion
0.56	GO:0048471	perinuclear region of cytoplasm

sp|Q13882|PTK6_HUMAN
Protein-tyrosine kinase 6
Search

0.57	Tyrosine-protein kinase STK

0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.59	GO:0060575	intestinal epithelial cell differentiation
0.58	GO:0061099	negative regulation of protein tyrosine kinase activity
0.58	GO:0071300	cellular response to retinoic acid
0.57	GO:0046777	protein autophosphorylation
0.57	GO:0007259	JAK-STAT cascade
0.56	GO:0010976	positive regulation of neuron projection development
0.55	GO:0045926	negative regulation of growth
0.55	GO:0016477	cell migration
0.47	GO:0045087	innate immune response

0.77	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.51	GO:0042802	identical protein binding
0.45	GO:0005102	receptor binding
0.34	GO:0004601	peroxidase activity
0.34	GO:0005249	voltage-gated potassium channel activity
0.33	GO:0003746	translation elongation factor activity

0.56	GO:0001726	ruffle
0.53	GO:0016604	nuclear body
0.49	GO:0005829	cytosol
0.48	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.34	GO:0008076	voltage-gated potassium channel complex
0.34	GO:0005912	adherens junction

0.77	EC:2.7.10.2	GO:0004715
0.34	KEGG:R03532	GO:0004601

sp|Q13884|SNTB1_HUMAN
Beta-1-syntrophin
Search

SNTB1

0.96	LOW QUALITY PROTEIN: beta-1-syntrophin

0.39	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation
0.39	GO:0006936	muscle contraction
0.39	GO:0060307	regulation of ventricular cardiac muscle cell membrane repolarization
0.38	GO:0086001	cardiac muscle cell action potential
0.38	GO:1902305	regulation of sodium ion transmembrane transport
0.38	GO:0070252	actin-mediated cell contraction
0.38	GO:0002027	regulation of heart rate
0.38	GO:0060047	heart contraction
0.35	GO:0065009	regulation of molecular function
0.35	GO:0050808	synapse organization

0.62	GO:0005198	structural molecule activity
0.40	GO:0030165	PDZ domain binding
0.39	GO:0050998	nitric-oxide synthase binding
0.38	GO:0017080	sodium channel regulator activity
0.38	GO:0051117	ATPase binding
0.38	GO:0044325	ion channel binding
0.37	GO:0005516	calmodulin binding
0.36	GO:0003779	actin binding
0.34	GO:0005044	scavenger receptor activity

0.51	GO:0045202	synapse
0.44	GO:0043234	protein complex
0.38	GO:0042383	sarcolemma
0.38	GO:0030054	cell junction
0.35	GO:0005856	cytoskeleton
0.35	GO:0044459	plasma membrane part
0.33	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

sp|Q13885|TBB2A_HUMAN
Tubulin beta-2A chain
Search

0.57	Tubulin beta chain

0.71	GO:0007017	microtubule-based process
0.71	GO:0007010	cytoskeleton organization
0.53	GO:1902669	positive regulation of axon guidance
0.50	GO:0001764	neuron migration
0.35	GO:0031115	negative regulation of microtubule polymerization
0.33	GO:0070925	organelle assembly
0.33	GO:0022402	cell cycle process

0.77	GO:0005200	structural constituent of cytoskeleton
0.67	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0046982	protein heterodimerization activity
0.34	GO:0042288	MHC class I protein binding
0.34	GO:0003725	double-stranded RNA binding
0.34	GO:0031625	ubiquitin protein ligase binding

0.73	GO:0005874	microtubule
0.46	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.36	GO:0005634	nucleus
0.34	GO:0043209	myelin sheath
0.34	GO:0044297	cell body
0.34	GO:0031970	organelle envelope lumen
0.34	GO:0035770	ribonucleoprotein granule
0.33	GO:0012505	endomembrane system

sp|Q13886|KLF9_HUMAN
Krueppel-like factor 9
Search

KLF9

0.95	Kruppel like factor 9

0.64	GO:0071387	cellular response to cortisol stimulus
0.61	GO:0097067	cellular response to thyroid hormone stimulus
0.61	GO:0010839	negative regulation of keratinocyte proliferation
0.57	GO:0007623	circadian rhythm
0.39	GO:0006357	regulation of transcription by RNA polymerase II
0.39	GO:0031018	endocrine pancreas development
0.38	GO:0050847	progesterone receptor signaling pathway
0.38	GO:0007566	embryo implantation
0.37	GO:0006366	transcription by RNA polymerase II
0.37	GO:0045893	positive regulation of transcription, DNA-templated

0.51	GO:0003676	nucleic acid binding
0.39	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.35	GO:0046872	metal ion binding

0.51	GO:0005654	nucleoplasm
0.50	GO:0005829	cytosol
0.43	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q13887|KLF5_HUMAN
Krueppel-like factor 5
Search

KLF5

0.96	Kruppel like factor 5

0.59	GO:0032534	regulation of microvillus assembly
0.58	GO:0060576	intestinal epithelial cell development
0.58	GO:0030033	microvillus assembly
0.56	GO:0045600	positive regulation of fat cell differentiation
0.56	GO:0035914	skeletal muscle cell differentiation
0.55	GO:1990830	cellular response to leukemia inhibitory factor
0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.54	GO:0001525	angiogenesis

0.59	GO:0003700	DNA binding transcription factor activity
0.53	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.39	GO:0008134	transcription factor binding
0.33	GO:0046872	metal ion binding

0.49	GO:0005794	Golgi apparatus
0.48	GO:0005654	nucleoplasm

sp|Q13888|TF2H2_HUMAN
General transcription factor IIH subunit 2
Search

GTF2H2

0.92	General transcription factor IIH polypeptide 2

0.73	GO:0006289	nucleotide-excision repair
0.58	GO:0006351	transcription, DNA-templated
0.45	GO:0006357	regulation of transcription by RNA polymerase II
0.38	GO:0002031	G-protein coupled receptor internalization
0.36	GO:0006468	protein phosphorylation
0.35	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.35	GO:0006359	regulation of transcription by RNA polymerase III
0.35	GO:0009411	response to UV
0.35	GO:0006915	apoptotic process
0.35	GO:0031334	positive regulation of protein complex assembly

0.61	GO:0008270	zinc ion binding
0.49	GO:0003676	nucleic acid binding
0.40	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity
0.37	GO:0047485	protein N-terminus binding
0.37	GO:0008094	DNA-dependent ATPase activity
0.36	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.35	GO:0001026	TFIIIB-type transcription factor activity
0.34	GO:0004146	dihydrofolate reductase activity
0.33	GO:0016874	ligase activity
0.33	GO:0003700	DNA binding transcription factor activity

0.81	GO:0000439	core TFIIH complex
0.51	GO:0005675	holo TFIIH complex
0.38	GO:0016607	nuclear speck
0.36	GO:0005669	transcription factor TFIID complex
0.35	GO:0000126	transcription factor TFIIIB complex
0.30	GO:0016020	membrane

0.40

EC:2.7.11.23

GO:0008353

sp|Q13889|TF2H3_HUMAN
General transcription factor IIH subunit 3
Search

GTF2H3

0.95	General transcription factor IIH subunit 3

0.73	GO:0006289	nucleotide-excision repair
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.51	GO:0006366	transcription by RNA polymerase II
0.47	GO:0006468	protein phosphorylation
0.40	GO:0043043	peptide biosynthetic process
0.36	GO:0006362	transcription elongation from RNA polymerase I promoter
0.35	GO:0006363	termination of RNA polymerase I transcription
0.35	GO:0006361	transcription initiation from RNA polymerase I promoter

0.58	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity
0.55	GO:0047485	protein N-terminus binding
0.50	GO:0008094	DNA-dependent ATPase activity
0.44	GO:0003684	damaged DNA binding
0.43	GO:0008135	translation factor activity, RNA binding
0.34	GO:0046872	metal ion binding
0.33	GO:0003700	DNA binding transcription factor activity
0.33	GO:0043022	ribosome binding
0.33	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.33	GO:0003779	actin binding

0.81	GO:0000439	core TFIIH complex
0.56	GO:0005675	holo TFIIH complex
0.56	GO:0097550	transcriptional preinitiation complex
0.52	GO:0005669	transcription factor TFIID complex
0.33	GO:0005759	mitochondrial matrix
0.33	GO:0005665	DNA-directed RNA polymerase II, core complex
0.32	GO:0031966	mitochondrial membrane
0.32	GO:0019866	organelle inner membrane
0.32	GO:0033179	proton-transporting V-type ATPase, V0 domain
0.32	GO:0030286	dynein complex

0.58

EC:2.7.11.23

GO:0008353

sp|Q13895|BYST_HUMAN
Bystin
Search

BYSL

0.85	Bystin like

0.85	GO:0001829	trophectodermal cell differentiation
0.81	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.79	GO:0008283	cell proliferation
0.41	GO:0007155	cell adhesion
0.40	GO:0007565	female pregnancy
0.40	GO:0071347	cellular response to interleukin-1
0.40	GO:0071222	cellular response to lipopolysaccharide
0.39	GO:0071363	cellular response to growth factor stimulus
0.39	GO:0007420	brain development
0.39	GO:0071407	cellular response to organic cyclic compound

0.38	GO:0003723	RNA binding
0.36	GO:0005515	protein binding

0.80	GO:0045177	apical part of cell
0.73	GO:0005730	nucleolus
0.49	GO:0005737	cytoplasm
0.38	GO:0005874	microtubule
0.38	GO:0005654	nucleoplasm
0.37	GO:0042995	cell projection
0.30	GO:0031224	intrinsic component of membrane

sp|Q13901|C1D_HUMAN
Nuclear nucleic acid-binding protein C1D
Search

C1D

0.94	Putative dna-binding protein c1d involved in regulation of double-strand break repair

0.77	GO:0000460	maturation of 5.8S rRNA
0.63	GO:0045892	negative regulation of transcription, DNA-templated
0.49	GO:0006915	apoptotic process
0.41	GO:0006351	transcription, DNA-templated

0.77	GO:0016922	ligand-dependent nuclear receptor binding
0.71	GO:0003714	transcription corepressor activity
0.57	GO:0003723	RNA binding
0.52	GO:0003677	DNA binding

0.71	GO:0017053	transcriptional repressor complex
0.70	GO:0005730	nucleolus
0.63	GO:0000178	exosome (RNase complex)
0.39	GO:0005737	cytoplasm
0.38	GO:0005654	nucleoplasm

sp|Q13905|RPGF1_HUMAN
Rap guanine nucleotide exchange factor 1
Search

RAPGEF1

0.71	Guanine nucleotide exchange factor

0.76	GO:0007264	small GTPase mediated signal transduction
0.66	GO:0065009	regulation of molecular function
0.61	GO:0038180	nerve growth factor signaling pathway
0.59	GO:0061028	establishment of endothelial barrier
0.59	GO:0071320	cellular response to cAMP
0.58	GO:1901888	regulation of cell junction assembly
0.57	GO:0010976	positive regulation of neuron projection development
0.53	GO:2000178	negative regulation of neural precursor cell proliferation
0.52	GO:0048008	platelet-derived growth factor receptor signaling pathway
0.52	GO:0051898	negative regulation of protein kinase B signaling

0.75	GO:0005085	guanyl-nucleotide exchange factor activity
0.53	GO:0017016	Ras GTPase binding
0.41	GO:0005070	SH3/SH2 adaptor activity
0.38	GO:0017124	SH3 domain binding
0.37	GO:0004871	signal transducer activity

0.55	GO:0005769	early endosome
0.40	GO:0030670	phagocytic vesicle membrane
0.38	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0005829	cytosol
0.35	GO:0043234	protein complex

sp|Q13907|IDI1_HUMAN
Isopentenyl-diphosphate Delta-isomerase 1
Search

IDI1

0.96	Isopentenyl-diphosphate delta isomerase 1

0.71	GO:0008299	isoprenoid biosynthetic process
0.45	GO:0046490	isopentenyl diphosphate metabolic process
0.44	GO:0008654	phospholipid biosynthetic process
0.42	GO:0006695	cholesterol biosynthetic process
0.41	GO:0050993	dimethylallyl diphosphate metabolic process
0.37	GO:0035634	response to stilbenoid
0.35	GO:0045540	regulation of cholesterol biosynthetic process
0.35	GO:0045338	farnesyl diphosphate metabolic process

0.81	GO:0004452	isopentenyl-diphosphate delta-isomerase activity
0.51	GO:0016787	hydrolase activity
0.36	GO:0030145	manganese ion binding
0.35	GO:0000287	magnesium ion binding
0.32	GO:0008483	transaminase activity

0.47	GO:0005777	peroxisome
0.34	GO:0005829	cytosol
0.34	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

0.81	EC:5.3.3.2	GO:0004452
0.81	KEGG:R01123	GO:0004452

sp|Q13936|CAC1C_HUMAN
Voltage-dependent L-type calcium channel subunit alpha-1C
Search

CACNA1C

0.54	Voltage-dependent L-type calcium channel subunit alpha

0.78	GO:0034765	regulation of ion transmembrane transport
0.77	GO:0070588	calcium ion transmembrane transport
0.60	GO:0098912	membrane depolarization during atrial cardiac muscle cell action potential
0.59	GO:0086045	membrane depolarization during AV node cell action potential
0.58	GO:0098911	regulation of ventricular cardiac muscle cell action potential
0.58	GO:0007507	heart development
0.57	GO:0048598	embryonic morphogenesis
0.57	GO:0086091	regulation of heart rate by cardiac conduction
0.56	GO:0035136	forelimb morphogenesis
0.54	GO:0007204	positive regulation of cytosolic calcium ion concentration

0.82	GO:0005245	voltage-gated calcium channel activity
0.57	GO:0051393	alpha-actinin binding
0.53	GO:0005516	calmodulin binding
0.39	GO:1905030	voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential
0.36	GO:0051721	protein phosphatase 2A binding
0.36	GO:0044325	ion channel binding
0.36	GO:0031369	translation initiation factor binding
0.35	GO:0046872	metal ion binding
0.35	GO:0019904	protein domain specific binding

0.81	GO:0005891	voltage-gated calcium channel complex
0.57	GO:0030315	T-tubule
0.55	GO:0014069	postsynaptic density
0.41	GO:0030018	Z disc
0.39	GO:0002095	caveolar macromolecular signaling complex
0.37	GO:0043198	dendritic shaft
0.36	GO:0043025	neuronal cell body
0.36	GO:0045211	postsynaptic membrane
0.36	GO:0042734	presynaptic membrane
0.33	GO:0005634	nucleus

sp|Q13938|CAYP1_HUMAN
Calcyphosin
Search

CAPS

0.94	Calcyphosine like

0.34

GO:0035556

intracellular signal transduction

0.70

GO:0005509

calcium ion binding

0.36	GO:0070062	extracellular exosome
0.34	GO:0005737	cytoplasm

sp|Q13939|CALI_HUMAN
Calicin
Search

CCIN

0.97

Calicin

0.82	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.61	GO:0007283	spermatogenesis
0.56	GO:0030154	cell differentiation
0.55	GO:0007275	multicellular organism development

0.74	GO:0003779	actin binding
0.74	GO:0004842	ubiquitin-protein transferase activity

0.83	GO:0031463	Cul3-RING ubiquitin ligase complex
0.74	GO:0015629	actin cytoskeleton
0.72	GO:0033150	cytoskeletal calyx
0.44	GO:0005634	nucleus

0.74

GO:0004842

sp|Q13946|PDE7A_HUMAN
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
Search

PDE7A

0.54	Phosphodiesterase

0.60	GO:0007165	signal transduction
0.38	GO:0006198	cAMP catabolic process

0.78	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.53	GO:0046872	metal ion binding

0.34	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.78

GO:0004114

sp|Q13950|RUNX2_HUMAN
Runt-related transcription factor 2
Search

RUNX2

0.90	Runt-related transcription factor

0.67	GO:0045893	positive regulation of transcription, DNA-templated
0.58	GO:0002062	chondrocyte differentiation
0.57	GO:0002051	osteoblast fate commitment
0.56	GO:0032332	positive regulation of chondrocyte differentiation
0.56	GO:0042487	regulation of odontogenesis of dentin-containing tooth
0.56	GO:0002076	osteoblast development
0.55	GO:0001958	endochondral ossification
0.55	GO:0035115	embryonic forelimb morphogenesis
0.55	GO:0040036	regulation of fibroblast growth factor receptor signaling pathway
0.55	GO:0045879	negative regulation of smoothened signaling pathway

0.60	GO:0003700	DNA binding transcription factor activity
0.55	GO:0043425	bHLH transcription factor binding
0.54	GO:0030554	adenyl nucleotide binding
0.54	GO:0003677	DNA binding
0.54	GO:0070491	repressing transcription factor binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0003682	chromatin binding
0.50	GO:0019904	protein domain specific binding

0.61	GO:0005634	nucleus
0.49	GO:0005667	transcription factor complex
0.48	GO:0000785	chromatin
0.47	GO:0031974	membrane-enclosed lumen
0.38	GO:0005737	cytoplasm

sp|Q13951|PEBB_HUMAN
Core-binding factor subunit beta
Search

CBFB

0.97	Core-binding factor beta subunit

0.56	GO:0030097	hemopoiesis
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:0048468	cell development
0.54	GO:0001649	osteoblast differentiation
0.52	GO:0000209	protein polyubiquitination
0.52	GO:0046649	lymphocyte activation
0.52	GO:0021700	developmental maturation
0.48	GO:1902680	positive regulation of RNA biosynthetic process
0.48	GO:0010628	positive regulation of gene expression
0.48	GO:0060047	heart contraction

0.77	GO:0003713	transcription coactivator activity
0.44	GO:0046982	protein heterodimerization activity
0.40	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.39	GO:0003677	DNA binding
0.34	GO:0003700	DNA binding transcription factor activity

0.60	GO:0005634	nucleus
0.48	GO:0030018	Z disc
0.45	GO:0005667	transcription factor complex
0.40	GO:0044446	intracellular organelle part
0.36	GO:0043233	organelle lumen
0.30	GO:0016020	membrane

sp|Q13952|NFYC_HUMAN
Nuclear transcription factor Y subunit gamma
Search

NFYC

0.62	Nuclear transcription factor Y subunit gamma

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.44	GO:0051254	positive regulation of RNA metabolic process
0.43	GO:0010557	positive regulation of macromolecule biosynthetic process
0.43	GO:0031328	positive regulation of cellular biosynthetic process
0.43	GO:0045540	regulation of cholesterol biosynthetic process
0.40	GO:0060041	retina development in camera-type eye
0.38	GO:0006457	protein folding

0.74	GO:0046982	protein heterodimerization activity
0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.46	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.40	GO:0003713	transcription coactivator activity
0.39	GO:0008134	transcription factor binding

0.83	GO:0016602	CCAAT-binding factor complex
0.49	GO:0032993	protein-DNA complex
0.48	GO:0005654	nucleoplasm

sp|Q13956|CNCG_HUMAN
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma
Search

PDE6H

0.95	Cone phosphodiesterase beta subunit

0.76	GO:0007601	visual perception
0.51	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway
0.51	GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway
0.50	GO:0000187	activation of MAPK activity
0.38	GO:0050896	response to stimulus
0.36	GO:0043086	negative regulation of catalytic activity
0.36	GO:0022400	regulation of rhodopsin mediated signaling pathway
0.34	GO:0198738	cell-cell signaling by wnt

0.85	GO:0030553	cGMP binding
0.77	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.39	GO:0030507	spectrin binding
0.36	GO:0004857	enzyme inhibitor activity
0.33	GO:0008270	zinc ion binding

0.38	GO:0097381	photoreceptor disc membrane
0.35	GO:0042622	photoreceptor outer segment membrane

0.77

GO:0004114

sp|Q13972|RGRF1_HUMAN
Ras-specific guanine nucleotide-releasing factor 1
Search

RASGRF1

0.93	Ras protein specific guanine nucleotide releasing factor 1

0.78	GO:0035023	regulation of Rho protein signal transduction
0.76	GO:0007264	small GTPase mediated signal transduction
0.66	GO:0065009	regulation of molecular function
0.53	GO:0035020	regulation of Rac protein signal transduction
0.53	GO:0034976	response to endoplasmic reticulum stress
0.52	GO:1900449	regulation of glutamate receptor signaling pathway
0.52	GO:0048168	regulation of neuronal synaptic plasticity
0.50	GO:1904062	regulation of cation transmembrane transport
0.49	GO:0008283	cell proliferation
0.49	GO:0031175	neuron projection development

0.77	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.53	GO:0035254	glutamate receptor binding
0.35	GO:0008234	cysteine-type peptidase activity
0.32	GO:0004797	thymidine kinase activity
0.32	GO:0030971	receptor tyrosine kinase binding
0.32	GO:0008022	protein C-terminus binding
0.32	GO:0005096	GTPase activator activity
0.31	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.51	GO:0030426	growth cone
0.45	GO:0005829	cytosol
0.36	GO:0005783	endoplasmic reticulum
0.33	GO:0005886	plasma membrane
0.32	GO:0097440	apical dendrite
0.32	GO:0043025	neuronal cell body
0.30	GO:0016021	integral component of membrane

0.35

GO:0008234

sp|Q13976|KGP1_HUMAN
cGMP-dependent protein kinase 1
Search

0.84	cGMP-dependent protein kinase

0.63	GO:0006468	protein phosphorylation
0.55	GO:0090331	negative regulation of platelet aggregation
0.54	GO:1904753	negative regulation of vascular associated smooth muscle cell migration
0.53	GO:1904706	negative regulation of vascular smooth muscle cell proliferation
0.51	GO:0060087	relaxation of vascular smooth muscle
0.51	GO:0019934	cGMP-mediated signaling
0.49	GO:0001764	neuron migration
0.49	GO:0016358	dendrite development
0.48	GO:0043087	regulation of GTPase activity
0.48	GO:0030900	forebrain development

0.85	GO:0004692	cGMP-dependent protein kinase activity
0.74	GO:0030553	cGMP binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.53	GO:0005246	calcium channel regulator activity
0.38	GO:0042802	identical protein binding
0.38	GO:0008603	cAMP-dependent protein kinase regulator activity
0.36	GO:0048273	mitogen-activated protein kinase p38 binding
0.34	GO:0046983	protein dimerization activity

0.44	GO:0005794	Golgi apparatus
0.40	GO:0005886	plasma membrane
0.38	GO:0005952	cAMP-dependent protein kinase complex
0.36	GO:0005829	cytosol
0.35	GO:0001669	acrosomal vesicle
0.34	GO:0005654	nucleoplasm
0.30	GO:0016021	integral component of membrane

0.85

EC:2.7.11.12

GO:0004692

sp|Q14002|CEAM7_HUMAN
Carcinoembryonic antigen-related cell adhesion molecule 7
Search

0.91	Pregnancy-specific beta-1-glycoprotein 5

0.53	GO:0007565	female pregnancy
0.48	GO:0016477	cell migration
0.46	GO:0043317	regulation of cytotoxic T cell degranulation
0.45	GO:0002859	negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
0.45	GO:0043312	neutrophil degranulation
0.45	GO:0001915	negative regulation of T cell mediated cytotoxicity
0.44	GO:0030334	regulation of cell migration
0.44	GO:0043301	negative regulation of leukocyte degranulation
0.44	GO:0050860	negative regulation of T cell receptor signaling pathway
0.43	GO:0090505	epiboly involved in wound healing

0.44	GO:0031005	filamin binding
0.43	GO:1990782	protein tyrosine kinase binding
0.42	GO:0019903	protein phosphatase binding
0.42	GO:0042803	protein homodimerization activity
0.40	GO:0003779	actin binding
0.38	GO:0015125	bile acid transmembrane transporter activity
0.38	GO:0034235	GPI anchor binding
0.37	GO:0005516	calmodulin binding

0.49	GO:0005576	extracellular region
0.44	GO:0031225	anchored component of membrane
0.44	GO:0030667	secretory granule membrane
0.43	GO:0042101	T cell receptor complex
0.42	GO:0042581	specific granule
0.42	GO:0009986	cell surface
0.41	GO:0070820	tertiary granule
0.41	GO:0042582	azurophil granule
0.41	GO:0005911	cell-cell junction
0.40	GO:0016323	basolateral plasma membrane

sp|Q14003|KCNC3_HUMAN
Potassium voltage-gated channel subfamily C member 3
Search

KCNC3

0.92	Potassium voltage-gated channel subfamily C member 3

0.75	GO:0051260	protein homooligomerization
0.75	GO:0034765	regulation of ion transmembrane transport
0.73	GO:0071805	potassium ion transmembrane transport
0.56	GO:0051262	protein tetramerization
0.43	GO:0046928	regulation of neurotransmitter secretion
0.34	GO:0006508	proteolysis

0.78	GO:0005249	voltage-gated potassium channel activity
0.35	GO:0070001	aspartic-type peptidase activity
0.34	GO:0004175	endopeptidase activity

0.78	GO:0008076	voltage-gated potassium channel complex
0.47	GO:0032591	dendritic spine membrane
0.45	GO:0042734	presynaptic membrane
0.45	GO:0043204	perikaryon
0.43	GO:0030424	axon
0.43	GO:0031594	neuromuscular junction
0.43	GO:0043679	axon terminus
0.43	GO:0032809	neuronal cell body membrane
0.42	GO:0005938	cell cortex
0.42	GO:0030054	cell junction

sp|Q14004|CDK13_HUMAN
Cyclin-dependent kinase 13
Search

CDK13

0.97	LOW QUALITY PROTEIN: cyclin-dependent kinase 13

0.63	GO:2000737	negative regulation of stem cell differentiation
0.63	GO:0006468	protein phosphorylation
0.63	GO:0000380	alternative mRNA splicing, via spliceosome
0.58	GO:0030097	hemopoiesis
0.54	GO:0006357	regulation of transcription by RNA polymerase II
0.49	GO:0006368	transcription elongation from RNA polymerase II promoter
0.46	GO:0045893	positive regulation of transcription, DNA-templated
0.46	GO:0051726	regulation of cell cycle
0.39	GO:0043312	neutrophil degranulation
0.37	GO:0008284	positive regulation of cell proliferation

0.64	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity
0.61	GO:0030332	cyclin binding
0.57	GO:0019901	protein kinase binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0004693	cyclin-dependent protein serine/threonine kinase activity
0.47	GO:0044212	transcription regulatory region DNA binding
0.46	GO:0008134	transcription factor binding
0.36	GO:0003723	RNA binding

0.67	GO:0002945	cyclin K-CDK13 complex
0.63	GO:0019908	nuclear cyclin-dependent protein kinase holoenzyme complex
0.59	GO:0016607	nuclear speck
0.54	GO:0005794	Golgi apparatus
0.52	GO:0005829	cytosol
0.50	GO:0032806	carboxy-terminal domain protein kinase complex
0.49	GO:0008023	transcription elongation factor complex
0.44	GO:0005694	chromosome
0.39	GO:1904813	ficolin-1-rich granule lumen
0.39	GO:0005615	extracellular space

0.64

EC:2.7.11.23

GO:0008353

sp|Q14005|IL16_HUMAN
Pro-interleukin-16
Search

IL16

0.91	Pro-interleukin-16

0.72	GO:0010469	regulation of receptor activity
0.68	GO:0006935	chemotaxis
0.63	GO:0050930	induction of positive chemotaxis
0.59	GO:0050900	leukocyte migration
0.59	GO:0051924	regulation of calcium ion transport
0.50	GO:0070887	cellular response to chemical stimulus
0.38	GO:0006351	transcription, DNA-templated
0.37	GO:2001141	regulation of RNA biosynthetic process
0.37	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.37	GO:0010468	regulation of gene expression

0.77	GO:0005125	cytokine activity
0.56	GO:0042609	CD4 receptor binding

0.70	GO:0005615	extracellular space
0.59	GO:0005634	nucleus
0.51	GO:0005829	cytosol
0.50	GO:0031974	membrane-enclosed lumen
0.45	GO:0044446	intracellular organelle part
0.44	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q14008|CKAP5_HUMAN
Cytoskeleton-associated protein 5
Search

CKAP5

0.89	Cytoskeleton-associated protein 5

0.85	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity
0.82	GO:0007098	centrosome cycle
0.80	GO:0007051	spindle organization
0.62	GO:0046785	microtubule polymerization
0.42	GO:0097711	ciliary basal body-plasma membrane docking
0.42	GO:0051236	establishment of RNA localization
0.42	GO:0050657	nucleic acid transport
0.41	GO:0007019	microtubule depolymerization
0.41	GO:0000086	G2/M transition of mitotic cell cycle
0.40	GO:0010389	regulation of G2/M transition of mitotic cell cycle

0.78	GO:0045296	cadherin binding
0.64	GO:0051010	microtubule plus-end binding
0.38	GO:0043021	ribonucleoprotein complex binding

0.85	GO:0035371	microtubule plus-end
0.80	GO:0000930	gamma-tubulin complex
0.79	GO:0000922	spindle pole
0.78	GO:0000776	kinetochore
0.77	GO:0005813	centrosome
0.71	GO:0005730	nucleolus
0.54	GO:0005886	plasma membrane
0.43	GO:0000779	condensed chromosome, centromeric region
0.38	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q14011|CIRBP_HUMAN
Cold-inducible RNA-binding protein
Search

CIRBP

0.90	Cold inducible RNA binding protein transcript variant 1

0.54	GO:0034063	stress granule assembly
0.51	GO:0009409	response to cold
0.51	GO:0030308	negative regulation of cell growth
0.51	GO:1902806	regulation of cell cycle G1/S phase transition
0.49	GO:0017148	negative regulation of translation
0.43	GO:0033554	cellular response to stress
0.43	GO:0048255	mRNA stabilization
0.41	GO:0045727	positive regulation of translation
0.40	GO:0009411	response to UV
0.39	GO:0060212	negative regulation of nuclear-transcribed mRNA poly(A) tail shortening

0.59	GO:0003723	RNA binding
0.53	GO:0030371	translation repressor activity
0.36	GO:0005515	protein binding

0.51	GO:0010494	cytoplasmic stress granule
0.48	GO:0005730	nucleolus
0.47	GO:0005654	nucleoplasm
0.35	GO:0005840	ribosome
0.30	GO:0016020	membrane

sp|Q14012|KCC1A_HUMAN
Calcium/calmodulin-dependent protein kinase type 1
Search

CAMK1

0.86	Calcium/calmodulin-dependent protein kinase Ia

0.63	GO:0006468	protein phosphorylation
0.59	GO:0010976	positive regulation of neuron projection development
0.59	GO:0051835	positive regulation of synapse structural plasticity
0.58	GO:0050773	regulation of dendrite development
0.56	GO:0060143	positive regulation of syncytium formation by plasma membrane fusion
0.56	GO:0046827	positive regulation of protein export from nucleus
0.55	GO:1901985	positive regulation of protein acetylation
0.55	GO:0051149	positive regulation of muscle cell differentiation
0.55	GO:0033138	positive regulation of peptidyl-serine phosphorylation
0.55	GO:0032091	negative regulation of protein binding

0.66	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0005516	calmodulin binding

0.40	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm

0.66

GO:0004674

sp|Q14019|COTL1_HUMAN
Coactosin-like protein
Search

COTL1

0.97	Coactosin like F-actin binding protein 1

0.55	GO:0050832	defense response to fungus
0.36	GO:0043312	neutrophil degranulation
0.35	GO:0001755	neural crest cell migration
0.35	GO:0030041	actin filament polymerization

0.73	GO:0003779	actin binding
0.51	GO:0019899	enzyme binding

0.45	GO:0005622	intracellular
0.37	GO:0070062	extracellular exosome
0.36	GO:0031983	vesicle lumen
0.36	GO:0043228	non-membrane-bounded organelle
0.34	GO:0012505	endomembrane system

sp|Q14028|CNGB1_HUMAN
Cyclic nucleotide-gated cation channel beta-1
Search

CNGB1

0.91	Cyclic nucleotide-gated cation channel beta subunit

0.78	GO:0007601	visual perception
0.61	GO:0098655	cation transmembrane transport
0.52	GO:0035845	photoreceptor cell outer segment organization
0.52	GO:0050962	detection of light stimulus involved in sensory perception
0.52	GO:0001895	retina homeostasis
0.49	GO:0009584	detection of visible light
0.48	GO:0007602	phototransduction
0.47	GO:0007608	sensory perception of smell
0.46	GO:0033365	protein localization to organelle
0.43	GO:0042391	regulation of membrane potential

0.86	GO:0005221	intracellular cyclic nucleotide activated cation channel activity
0.53	GO:0030553	cGMP binding
0.43	GO:0005249	voltage-gated potassium channel activity
0.34	GO:0003777	microtubule motor activity
0.34	GO:0008017	microtubule binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.31	GO:0042803	protein homodimerization activity

0.51	GO:0001750	photoreceptor outer segment
0.44	GO:1902495	transmembrane transporter complex
0.40	GO:0005887	integral component of plasma membrane
0.37	GO:0043195	terminal bouton
0.31	GO:0060170	ciliary membrane
0.31	GO:0043234	protein complex
0.31	GO:0005737	cytoplasm
0.30	GO:0031984	organelle subcompartment
0.30	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0098805	whole membrane

sp|Q14031|CO4A6_HUMAN
Collagen alpha-6(IV) chain
Search

COL4A6

0.86	Collagen type IV alpha 6 chain

0.61	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.54	GO:0071495	cellular response to endogenous stimulus
0.53	GO:0071310	cellular response to organic substance
0.52	GO:0043200	response to amino acid
0.51	GO:0030198	extracellular matrix organization
0.51	GO:0071229	cellular response to acid chemical
0.50	GO:1901699	cellular response to nitrogen compound
0.50	GO:0035987	endodermal cell differentiation
0.49	GO:0016525	negative regulation of angiogenesis
0.48	GO:1901701	cellular response to oxygen-containing compound

0.80

GO:0005201

extracellular matrix structural constituent

0.80	GO:0005604	basement membrane
0.77	GO:0005581	collagen trimer
0.63	GO:0098645	collagen network
0.45	GO:0005615	extracellular space
0.34	GO:0005788	endoplasmic reticulum lumen
0.34	GO:1903561	extracellular vesicle

sp|Q14032|BAAT_HUMAN
Bile acid-CoA:amino acid N-acyltransferase
Search

BAAT

0.93	Bile acid-CoA:amino acid N-acyltransferase

0.76	GO:0002152	bile acid conjugation
0.72	GO:0035383	thioester metabolic process
0.71	GO:0006699	bile acid biosynthetic process
0.70	GO:0019530	taurine metabolic process
0.62	GO:0006732	coenzyme metabolic process
0.60	GO:0006544	glycine metabolic process
0.53	GO:0006793	phosphorus metabolic process
0.46	GO:0006631	fatty acid metabolic process
0.46	GO:0031100	animal organ regeneration
0.45	GO:0001889	liver development

0.77	GO:0052817	very long chain acyl-CoA hydrolase activity
0.76	GO:0047963	glycine N-choloyltransferase activity
0.75	GO:0052815	medium-chain acyl-CoA hydrolase activity
0.59	GO:0005102	receptor binding
0.56	GO:0016410	N-acyltransferase activity
0.47	GO:0102991	myristoyl-CoA hydrolase activity
0.46	GO:0016290	palmitoyl-CoA hydrolase activity
0.41	GO:0052689	carboxylic ester hydrolase activity

0.64	GO:0005777	peroxisome
0.57	GO:0005829	cytosol
0.40	GO:0031907	microbody lumen

0.76	EC:2.3.1.65	GO:0047963
0.41	KEGG:R00630	GO:0052689

sp|Q14050|CO9A3_HUMAN
Collagen alpha-3(IX) chain
Search

COL9A3

0.97	Collagen type IX alpha 3 chain

0.60	GO:0008584	male gonad development
0.60	GO:0008585	female gonad development
0.37	GO:0007155	cell adhesion
0.36	GO:0030198	extracellular matrix organization
0.35	GO:0032835	glomerulus development
0.35	GO:1905812	regulation of motor neuron axon guidance
0.34	GO:0001654	eye development
0.34	GO:0010951	negative regulation of endopeptidase activity
0.33	GO:0045112	integrin biosynthetic process
0.33	GO:1903225	negative regulation of endodermal cell differentiation

0.55	GO:0005201	extracellular matrix structural constituent
0.36	GO:0004872	receptor activity
0.35	GO:0042302	structural constituent of cuticle
0.34	GO:0004867	serine-type endopeptidase inhibitor activity
0.34	GO:0043394	proteoglycan binding
0.33	GO:0008201	heparin binding
0.33	GO:0048407	platelet-derived growth factor binding
0.31	GO:0016853	isomerase activity
0.31	GO:0016740	transferase activity

0.75	GO:0005581	collagen trimer
0.48	GO:0031012	extracellular matrix
0.34	GO:0005788	endoplasmic reticulum lumen
0.34	GO:0099081	supramolecular polymer
0.30	GO:0016020	membrane

0.31

GO:0016853

sp|Q14055|CO9A2_HUMAN
Collagen alpha-2(IX) chain
Search

COL9A2

0.91	Collagen type XIII alpha 1 chain

0.41	GO:0007155	cell adhesion
0.40	GO:0007275	multicellular organism development
0.39	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.39	GO:0007528	neuromuscular junction development
0.39	GO:0030198	extracellular matrix organization
0.38	GO:0009653	anatomical structure morphogenesis
0.37	GO:0009888	tissue development
0.37	GO:0060322	head development
0.36	GO:0071230	cellular response to amino acid stimulus
0.36	GO:0030154	cell differentiation

0.55	GO:0005201	extracellular matrix structural constituent
0.39	GO:0042302	structural constituent of cuticle
0.37	GO:0048407	platelet-derived growth factor binding
0.35	GO:0004867	serine-type endopeptidase inhibitor activity
0.34	GO:0008201	heparin binding
0.34	GO:0042802	identical protein binding
0.32	GO:0046872	metal ion binding
0.32	GO:0004252	serine-type endopeptidase activity
0.31	GO:0003723	RNA binding
0.31	GO:0030554	adenyl nucleotide binding

0.70	GO:0005581	collagen trimer
0.50	GO:0031012	extracellular matrix
0.37	GO:0099081	supramolecular polymer
0.37	GO:0031594	neuromuscular junction
0.36	GO:0005615	extracellular space
0.34	GO:0005788	endoplasmic reticulum lumen
0.34	GO:0030054	cell junction
0.32	GO:0005794	Golgi apparatus
0.30	GO:0016020	membrane

0.32

GO:0004252

sp|Q14061|COX17_HUMAN
Cytochrome c oxidase copper chaperone
Search

COX17

0.94	Mitochondrial cytochrome c oxidase copper chaperone

0.78	GO:0006825	copper ion transport
0.54	GO:1904734	positive regulation of electron transfer activity
0.54	GO:1904959	regulation of cytochrome-c oxidase activity
0.53	GO:0033617	mitochondrial respiratory chain complex IV assembly
0.50	GO:0032414	positive regulation of ion transmembrane transporter activity
0.50	GO:1904064	positive regulation of cation transmembrane transport
0.48	GO:0008284	positive regulation of cell proliferation
0.43	GO:0046688	response to copper ion
0.39	GO:0007507	heart development
0.39	GO:0007420	brain development

0.85	GO:0016531	copper chaperone activity
0.53	GO:1903136	cuprous ion binding
0.37	GO:0008047	enzyme activator activity
0.33	GO:0005515	protein binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0016874	ligase activity

0.79	GO:0005758	mitochondrial intermembrane space
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0016874

sp|Q14088|RB33A_HUMAN
Ras-related protein Rab-33A
Search

RAB33A

0.96	Small GTP-binding protein S10

0.52	GO:1903434	negative regulation of constitutive secretory pathway
0.52	GO:2000785	regulation of autophagosome assembly
0.51	GO:2000156	regulation of retrograde vesicle-mediated transport, Golgi to ER
0.51	GO:0019882	antigen processing and presentation
0.50	GO:1903358	regulation of Golgi organization
0.50	GO:0000042	protein targeting to Golgi
0.47	GO:0048705	skeletal system morphogenesis
0.47	GO:0000045	autophagosome assembly
0.35	GO:0050678	regulation of epithelial cell proliferation
0.35	GO:0001558	regulation of cell growth

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding
0.34	GO:0004767	sphingomyelin phosphodiesterase activity
0.34	GO:0003723	RNA binding

0.50	GO:0005796	Golgi lumen
0.37	GO:0000139	Golgi membrane
0.35	GO:0070062	extracellular exosome
0.33	GO:0005886	plasma membrane

0.34	EC:3.1.4.12	GO:0004767
0.34	KEGG:R02541	GO:0004767

sp|Q14093|CYLC2_HUMAN
Cylicin-2
Search

CYLC2

0.97	Cylicin, basic protein of sperm head cytoskeleton 2

0.69	GO:0007010	cytoskeleton organization
0.42	GO:0007283	spermatogenesis
0.40	GO:0030154	cell differentiation
0.40	GO:0007275	multicellular organism development
0.37	GO:0000412	histone peptidyl-prolyl isomerization
0.35	GO:0000453	enzyme-directed rRNA 2'-O-methylation
0.34	GO:0047497	mitochondrion transport along microtubule
0.34	GO:0061162	establishment of monopolar cell polarity
0.34	GO:0032387	negative regulation of intracellular transport
0.34	GO:0061387	regulation of extent of cell growth

0.74	GO:0005200	structural constituent of cytoskeleton
0.37	GO:0005528	FK506 binding
0.36	GO:0070039	rRNA (guanosine-2'-O-)-methyltransferase activity
0.36	GO:0008650	rRNA (uridine-2'-O-)-methyltransferase activity
0.36	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.34	GO:0000104	succinate dehydrogenase activity
0.34	GO:0004383	guanylate cyclase activity
0.34	GO:0030554	adenyl nucleotide binding
0.33	GO:0097367	carbohydrate derivative binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.46	GO:0043159	acrosomal matrix
0.46	GO:0033150	cytoskeletal calyx
0.39	GO:0005634	nucleus
0.36	GO:0070013	intracellular organelle lumen
0.36	GO:0030687	preribosome, large subunit precursor
0.35	GO:0045281	succinate dehydrogenase complex
0.34	GO:0001750	photoreceptor outer segment
0.34	GO:0014069	postsynaptic density
0.33	GO:0005874	microtubule
0.33	GO:0005829	cytosol

0.36

GO:0008650

sp|Q14094|CCNI_HUMAN
Cyclin-I
Search

CCNI

0.95

Cyclin I

0.73	GO:0051726	regulation of cell cycle
0.35	GO:0007283	spermatogenesis
0.34	GO:0045859	regulation of protein kinase activity
0.34	GO:0006457	protein folding

0.35	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032553	ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.35

GO:0016538

sp|Q14103|HNRPD_HUMAN
Heterogeneous nuclear ribonucleoprotein D0
Search

HNRNPD

0.96	Heterogeneous nuclear ribonucleoprotein D

0.64	GO:1905661	regulation of telomerase RNA reverse transcriptase activity
0.62	GO:0097167	circadian regulation of translation
0.61	GO:1904355	positive regulation of telomere capping
0.60	GO:0051973	positive regulation of telomerase activity
0.58	GO:0043488	regulation of mRNA stability
0.57	GO:0042752	regulation of circadian rhythm
0.54	GO:0045727	positive regulation of translation
0.45	GO:1990828	hepatocyte dedifferentiation
0.45	GO:1904586	cellular response to putrescine
0.44	GO:1904383	response to sodium phosphate

0.59	GO:0003723	RNA binding
0.56	GO:0042162	telomeric DNA binding
0.42	GO:0003680	AT DNA binding
0.42	GO:0042826	histone deacetylase binding
0.40	GO:0003682	chromatin binding
0.39	GO:0008134	transcription factor binding

0.61	GO:0019013	viral nucleocapsid
0.58	GO:0030529	intracellular ribonucleoprotein complex
0.51	GO:0005654	nucleoplasm
0.38	GO:0005829	cytosol
0.38	GO:0070062	extracellular exosome

sp|Q14106|TOB2_HUMAN
Protein Tob2
Search

TOB2

0.97	Transducer of erbB-2 2

0.79	GO:0008285	negative regulation of cell proliferation
0.69	GO:0030278	regulation of ossification
0.66	GO:0045596	negative regulation of cell differentiation
0.65	GO:0051241	negative regulation of multicellular organismal process
0.62	GO:0045670	regulation of osteoclast differentiation
0.61	GO:0060212	negative regulation of nuclear-transcribed mRNA poly(A) tail shortening
0.59	GO:0007184	SMAD protein import into nucleus
0.59	GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
0.57	GO:0051240	positive regulation of multicellular organismal process
0.56	GO:0030514	negative regulation of BMP signaling pathway

0.66	GO:0042809	vitamin D receptor binding
0.62	GO:0003714	transcription corepressor activity
0.57	GO:0030971	receptor tyrosine kinase binding
0.56	GO:0046332	SMAD binding

0.55	GO:0030014	CCR4-NOT complex
0.54	GO:0005829	cytosol
0.45	GO:0005634	nucleus

sp|Q14108|SCRB2_HUMAN
Lysosome membrane protein 2
Search

SCARB2

0.87	Scavenger receptor class B member 2

0.72	GO:1905123	regulation of glucosylceramidase activity
0.70	GO:0006622	protein targeting to lysosome
0.66	GO:0001508	action potential
0.41	GO:0030903	notochord development
0.38	GO:0010976	positive regulation of neuron projection development

0.65	GO:0004872	receptor activity
0.58	GO:0019899	enzyme binding

0.79	GO:0005764	lysosome
0.68	GO:0005775	vacuolar lumen
0.62	GO:0098852	lytic vacuole membrane
0.30	GO:0016021	integral component of membrane

sp|Q14112|NID2_HUMAN
Nidogen-2
Search

NID2

0.68	Nidogen 2a (osteonidogen)

0.78	GO:0007160	cell-matrix adhesion
0.41	GO:0032836	glomerular basement membrane development
0.40	GO:0010811	positive regulation of cell-substrate adhesion
0.34	GO:0006508	proteolysis
0.33	GO:0071711	basement membrane organization

0.69	GO:0005509	calcium ion binding
0.43	GO:0043236	laminin binding
0.43	GO:0043394	proteoglycan binding
0.42	GO:0005518	collagen binding
0.35	GO:0004222	metalloendopeptidase activity
0.34	GO:0008270	zinc ion binding

0.53	GO:0005604	basement membrane
0.46	GO:0005615	extracellular space
0.40	GO:0071944	cell periphery
0.39	GO:1903561	extracellular vesicle
0.38	GO:0009986	cell surface
0.30	GO:0031224	intrinsic component of membrane

0.35

GO:0004222

sp|Q14114|LRP8_HUMAN
Low-density lipoprotein receptor-related protein 8
Search

LRP8

0.84	Low density lipoprotein receptor-related protein 8, apolipoprotein e receptor

0.53	GO:0006898	receptor-mediated endocytosis
0.45	GO:0021541	ammon gyrus development
0.43	GO:0061003	positive regulation of dendritic spine morphogenesis
0.43	GO:0071397	cellular response to cholesterol
0.43	GO:0038026	reelin-mediated signaling pathway
0.42	GO:0032793	positive regulation of CREB transcription factor activity
0.42	GO:0061098	positive regulation of protein tyrosine kinase activity
0.42	GO:0021987	cerebral cortex development
0.41	GO:0001523	retinoid metabolic process
0.41	GO:0050804	modulation of chemical synaptic transmission

0.69	GO:0005509	calcium ion binding
0.63	GO:0030229	very-low-density lipoprotein particle receptor activity
0.44	GO:0038025	reelin receptor activity
0.43	GO:0008035	high-density lipoprotein particle binding
0.43	GO:0034185	apolipoprotein binding
0.43	GO:0005041	low-density lipoprotein receptor activity
0.42	GO:0019894	kinesin binding
0.33	GO:0048306	calcium-dependent protein binding

0.60	GO:0005901	caveola
0.57	GO:0043235	receptor complex
0.41	GO:0014069	postsynaptic density
0.41	GO:0043025	neuronal cell body
0.41	GO:0030425	dendrite
0.40	GO:0030424	axon
0.40	GO:0005875	microtubule associated complex
0.38	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

sp|Q14116|IL18_HUMAN
Interleukin-18
Search

IL18

0.97	Interleukin-18

0.80	GO:0006954	inflammatory response
0.75	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.64	GO:0042095	interferon-gamma biosynthetic process
0.61	GO:0035655	interleukin-18-mediated signaling pathway
0.61	GO:0051140	regulation of NK T cell proliferation
0.61	GO:0045630	positive regulation of T-helper 2 cell differentiation
0.61	GO:0032819	positive regulation of natural killer cell proliferation
0.61	GO:0051135	positive regulation of NK T cell activation
0.60	GO:0042104	positive regulation of activated T cell proliferation

0.80

GO:0005125

cytokine activity

0.73	GO:0005615	extracellular space
0.37	GO:0005622	intracellular
0.36	GO:1903561	extracellular vesicle

sp|Q14117|DPYS_HUMAN
Dihydropyrimidinase
Search

DPYS

0.66	LOW QUALITY PROTEIN: dihydropyrimidinase

0.54	GO:0006212	uracil catabolic process
0.40	GO:0006210	thymine catabolic process
0.39	GO:0019482	beta-alanine metabolic process
0.39	GO:0051289	protein homotetramerization
0.35	GO:0046135	pyrimidine nucleoside catabolic process

0.60	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
0.55	GO:0051219	phosphoprotein binding
0.41	GO:0002059	thymine binding
0.41	GO:0002058	uracil binding
0.37	GO:0016597	amino acid binding
0.35	GO:0008270	zinc ion binding

0.46	GO:0005737	cytoplasm
0.37	GO:0070062	extracellular exosome

0.60

EC:3.5

GO:0016810

sp|Q14118|DAG1_HUMAN
Dystroglycan
Search

DAG1

0.92	Dystroglycan 1 (Dystrophin-associated glycoprotein 1)

0.85	GO:0007016	cytoskeletal anchoring at plasma membrane
0.61	GO:1904261	positive regulation of basement membrane assembly involved in embryonic body morphogenesis
0.58	GO:0021682	nerve maturation
0.58	GO:0010470	regulation of gastrulation
0.58	GO:0006509	membrane protein ectodomain proteolysis
0.58	GO:0051898	negative regulation of protein kinase B signaling
0.58	GO:0006607	NLS-bearing protein import into nucleus
0.58	GO:0010717	regulation of epithelial to mesenchymal transition
0.57	GO:0034453	microtubule anchoring
0.57	GO:0071679	commissural neuron axon guidance

0.70	GO:0005509	calcium ion binding
0.60	GO:0017166	vinculin binding
0.59	GO:0051393	alpha-actinin binding
0.59	GO:0042169	SH2 domain binding
0.59	GO:0008307	structural constituent of muscle
0.55	GO:0002162	dystroglycan binding
0.52	GO:0015631	tubulin binding
0.52	GO:0003779	actin binding
0.48	GO:0043236	laminin binding
0.37	GO:0043395	heparan sulfate proteoglycan binding

0.84	GO:0016010	dystrophin-associated glycoprotein complex
0.57	GO:0042383	sarcolemma
0.57	GO:0030175	filopodium
0.57	GO:0070938	contractile ring
0.56	GO:0033268	node of Ranvier
0.56	GO:0030027	lamellipodium
0.56	GO:0005604	basement membrane
0.55	GO:0005925	focal adhesion
0.53	GO:0009897	external side of plasma membrane
0.52	GO:0098857	membrane microdomain

sp|Q14119|VEZF1_HUMAN
Vascular endothelial zinc finger 1
Search

VEZF1

0.91	Vascular endothelial zinc finger 1

0.49	GO:0001885	endothelial cell development
0.47	GO:0001525	angiogenesis
0.45	GO:0006366	transcription by RNA polymerase II
0.45	GO:0045944	positive regulation of transcription by RNA polymerase II
0.33	GO:0006968	cellular defense response

0.51	GO:0003676	nucleic acid binding
0.47	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.32	GO:0046872	metal ion binding

0.44

GO:0005654

nucleoplasm

sp|Q14123|PDE1C_HUMAN
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C
Search

PDE1C

0.56	Phosphodiesterase

0.60	GO:0007165	signal transduction
0.47	GO:0007608	sensory perception of smell
0.37	GO:0051592	response to calcium ion
0.36	GO:0046069	cGMP catabolic process
0.35	GO:0046676	negative regulation of insulin secretion
0.35	GO:0006198	cAMP catabolic process

0.79	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.53	GO:0046872	metal ion binding
0.38	GO:0005516	calmodulin binding
0.35	GO:0030552	cAMP binding

0.48	GO:0005929	cilium
0.35	GO:0043025	neuronal cell body
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.79

GO:0004114

sp|Q14126|DSG2_HUMAN
Desmoglein-2
Search

DSG2

0.95	Putative cadherin egf lag seven-pass g-type receptor

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.70	GO:0003165	Purkinje myocyte development
0.69	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication
0.67	GO:0098911	regulation of ventricular cardiac muscle cell action potential
0.67	GO:0002934	desmosome organization
0.66	GO:0086091	regulation of heart rate by cardiac conduction
0.43	GO:0032570	response to progesterone
0.43	GO:0060135	maternal process involved in female pregnancy
0.38	GO:0070268	cornification
0.35	GO:0050821	protein stabilization

0.70	GO:0005509	calcium ion binding
0.61	GO:0050839	cell adhesion molecule binding
0.40	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication
0.37	GO:0045295	gamma-catenin binding

0.65	GO:0030057	desmosome
0.65	GO:0014704	intercalated disc
0.55	GO:0005886	plasma membrane
0.46	GO:0043227	membrane-bounded organelle
0.44	GO:0043229	intracellular organelle
0.41	GO:0045177	apical part of cell
0.40	GO:0043230	extracellular organelle
0.38	GO:0009986	cell surface
0.38	GO:0005615	extracellular space
0.35	GO:0098562	cytoplasmic side of membrane

sp|Q14129|DGCR6_HUMAN
Protein DGCR6
Search

DGCR6

0.97	DiGeorge syndrome critical region gene 6

0.54	GO:0032501	multicellular organismal process
0.51	GO:0007155	cell adhesion
0.51	GO:0009653	anatomical structure morphogenesis
0.47	GO:0009593	detection of chemical stimulus
0.45	GO:0007186	G-protein coupled receptor signaling pathway

0.47	GO:0004984	olfactory receptor activity
0.46	GO:0005515	protein binding
0.46	GO:0004930	G-protein coupled receptor activity

0.53	GO:0005578	proteinaceous extracellular matrix
0.52	GO:0005634	nucleus
0.40	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q14134|TRI29_HUMAN
Tripartite motif-containing protein 29
Search

TRIM29

0.96	Tripartite motif-containing protein 29

0.66	GO:1900181	negative regulation of protein localization to nucleus
0.61	GO:0000122	negative regulation of transcription by RNA polymerase II
0.61	GO:0098609	cell-cell adhesion
0.38	GO:0045087	innate immune response
0.36	GO:0006366	transcription by RNA polymerase II
0.32	GO:0000413	protein peptidyl-prolyl isomerization
0.32	GO:0006457	protein folding
0.32	GO:0046907	intracellular transport
0.31	GO:0055085	transmembrane transport

0.69	GO:0098641	cadherin binding involved in cell-cell adhesion
0.65	GO:0002039	p53 binding
0.63	GO:0008270	zinc ion binding
0.58	GO:0042802	identical protein binding
0.35	GO:0016874	ligase activity
0.34	GO:0003700	DNA binding transcription factor activity
0.32	GO:0003755	peptidyl-prolyl cis-trans isomerase activity

0.65	GO:0005913	cell-cell adherens junction
0.45	GO:0005622	intracellular
0.35	GO:0043227	membrane-bounded organelle
0.30	GO:0016020	membrane

0.35

GO:0016874

sp|Q14135|VGLL4_HUMAN
Transcription cofactor vestigial-like protein 4
Search

VGLL4

0.90	Vestigial like 4 (Drosophila)

0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.38	GO:0035329	hippo signaling

0.33	GO:0005622	intracellular
0.30	GO:0044425	membrane part

sp|Q14137|BOP1_HUMAN
Ribosome biogenesis protein BOP1
Search

BOP1

0.83	Ribosome biogenesis protein bop1-B

0.76	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.74	GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.49	GO:1901796	regulation of signal transduction by p53 class mediator
0.49	GO:0000479	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.48	GO:0008283	cell proliferation
0.47	GO:0035206	regulation of hemocyte proliferation
0.46	GO:0051726	regulation of cell cycle
0.46	GO:0000027	ribosomal large subunit assembly
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:2001141	regulation of RNA biosynthetic process

0.68	GO:0043021	ribonucleoprotein complex binding
0.35	GO:0005515	protein binding
0.35	GO:0003723	RNA binding
0.34	GO:0043565	sequence-specific DNA binding
0.33	GO:0003700	DNA binding transcription factor activity

0.74	GO:0030687	preribosome, large subunit precursor
0.72	GO:0005730	nucleolus
0.68	GO:0005654	nucleoplasm
0.51	GO:0030686	90S preribosome
0.42	GO:0043234	protein complex

sp|Q14139|UBE4A_HUMAN
Ubiquitin conjugation factor E4 A
Search

UBE4A

0.96	Ubiquitin conjugation factor E4 A

0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.72	GO:0016567	protein ubiquitination
0.47	GO:0036503	ERAD pathway

0.85	GO:0034450	ubiquitin-ubiquitin ligase activity
0.33	GO:0005515	protein binding

0.76	GO:0000151	ubiquitin ligase complex
0.40	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q14140|SRTD2_HUMAN
SERTA domain-containing protein 2
Search

SERTAD2

0.97	SERTA domain-containing protein 2

0.83	GO:0030308	negative regulation of cell growth
0.73	GO:0045893	positive regulation of transcription, DNA-templated
0.38	GO:0006351	transcription, DNA-templated

0.78	GO:0003713	transcription coactivator activity
0.36	GO:0005515	protein binding

0.69	GO:0005654	nucleoplasm
0.67	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q14141|SEPT6_HUMAN
Septin-6
Search

SEPT6

0.96	Septin-6 isoform B

0.45	GO:0035469	determination of pancreatic left/right asymmetry
0.45	GO:0071910	determination of liver left/right asymmetry
0.45	GO:0003140	determination of left/right asymmetry in lateral mesoderm
0.45	GO:0071907	determination of digestive tract left/right asymmetry
0.43	GO:0061371	determination of heart left/right asymmetry
0.42	GO:0060271	cilium assembly
0.37	GO:0007283	spermatogenesis
0.36	GO:0030154	cell differentiation
0.35	GO:0051301	cell division
0.35	GO:0007049	cell cycle

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding
0.32	GO:0003676	nucleic acid binding

0.85	GO:0031105	septin complex
0.54	GO:0032173	septin collar
0.54	GO:0097227	sperm annulus
0.51	GO:0032154	cleavage furrow
0.51	GO:0043679	axon terminus
0.50	GO:0005940	septin ring
0.49	GO:0008021	synaptic vesicle
0.37	GO:0030496	midbody
0.37	GO:0000777	condensed chromosome kinetochore
0.36	GO:0005819	spindle

sp|Q14142|TRI14_HUMAN
Tripartite motif-containing protein 14
Search

TRIM14

0.97	Tripartite motif-containing protein 14

0.69	GO:0032897	negative regulation of viral transcription
0.66	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.63	GO:0045087	innate immune response
0.38	GO:1903900	regulation of viral life cycle
0.36	GO:0002741	positive regulation of cytokine secretion involved in immune response
0.36	GO:0060340	positive regulation of type I interferon-mediated signaling pathway
0.36	GO:0010994	free ubiquitin chain polymerization
0.36	GO:0035458	cellular response to interferon-beta
0.36	GO:0010800	positive regulation of peptidyl-threonine phosphorylation
0.36	GO:2000679	positive regulation of transcription regulatory region DNA binding

0.60	GO:0008270	zinc ion binding
0.36	GO:0004842	ubiquitin-protein transferase activity
0.36	GO:1990782	protein tyrosine kinase binding
0.35	GO:0030674	protein binding, bridging
0.35	GO:0061659	ubiquitin-like protein ligase activity
0.35	GO:0016874	ligase activity
0.34	GO:0051015	actin filament binding
0.34	GO:0008134	transcription factor binding
0.33	GO:0043565	sequence-specific DNA binding
0.33	GO:0003700	DNA binding transcription factor activity

0.43	GO:0005622	intracellular
0.39	GO:0098805	whole membrane
0.38	GO:0098588	bounding membrane of organelle
0.38	GO:0019867	outer membrane
0.36	GO:0031975	envelope
0.34	GO:0017053	transcriptional repressor complex
0.33	GO:0005886	plasma membrane
0.32	GO:1990234	transferase complex
0.32	GO:0031974	membrane-enclosed lumen
0.30	GO:0044425	membrane part

0.35	EC:6	GO:0016874
0.36	KEGG:R03876	GO:0004842

sp|Q14145|KEAP1_HUMAN
Kelch-like ECH-associated protein 1
Search

KEAP1

0.91	Kelch-like ECH-associated protein 1b

0.73	GO:0016567	protein ubiquitination
0.72	GO:0071379	cellular response to prostaglandin stimulus
0.63	GO:0071466	cellular response to xenobiotic stimulus
0.53	GO:0042994	cytoplasmic sequestering of transcription factor
0.51	GO:0043433	negative regulation of DNA binding transcription factor activity
0.48	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process

0.73	GO:0008134	transcription factor binding
0.47	GO:0004842	ubiquitin-protein transferase activity

0.83

GO:0031463

Cul3-RING ubiquitin ligase complex

0.47

GO:0004842

sp|Q14146|URB2_HUMAN
Unhealthy ribosome biogenesis protein 2 homolog
Search

URB2

0.97	Unhealthy ribosome biogenesis protein 2

0.53

GO:0042254

ribosome biogenesis

0.83	GO:0016235	aggresome
0.80	GO:0030496	midbody
0.73	GO:0005730	nucleolus
0.30	GO:0031224	intrinsic component of membrane

sp|Q14147|DHX34_HUMAN
Probable ATP-dependent RNA helicase DHX34
Search

DHX34

0.96	DEAH (Asp-Glu-Ala-His) box polypeptide 34

0.61	GO:2000623	negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.54	GO:0000956	nuclear-transcribed mRNA catabolic process
0.42	GO:0006396	RNA processing
0.39	GO:0006506	GPI anchor biosynthetic process
0.38	GO:0097502	mannosylation
0.36	GO:0043009	chordate embryonic development

0.67	GO:0004386	helicase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0008186	RNA-dependent ATPase activity
0.45	GO:0003676	nucleic acid binding
0.42	GO:0140098	catalytic activity, acting on RNA
0.39	GO:0004584	dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity
0.34	GO:0052689	carboxylic ester hydrolase activity
0.32	GO:0046872	metal ion binding

0.37	GO:0005737	cytoplasm
0.33	GO:0005576	extracellular region
0.32	GO:1990904	ribonucleoprotein complex
0.32	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0016020	membrane

0.39	EC:2.4.1.130	GO:0004584
0.34	KEGG:R00630	GO:0052689

sp|Q14149|MORC3_HUMAN
MORC family CW-type zinc finger protein 3
Search

MORC3

0.95	MORC family CW-type zinc finger protein 3

0.63	GO:0048147	negative regulation of fibroblast proliferation
0.62	GO:0051457	maintenance of protein location in nucleus
0.59	GO:0007569	cell aging
0.59	GO:0018105	peptidyl-serine phosphorylation
0.58	GO:0050821	protein stabilization
0.57	GO:0009791	post-embryonic development
0.34	GO:0016032	viral process

0.62	GO:0008270	zinc ion binding
0.35	GO:0003723	RNA binding

0.61	GO:0016605	PML body
0.38	GO:0016363	nuclear matrix

sp|Q14151|SAFB2_HUMAN
Scaffold attachment factor B2
Search

sp|Q14152|EIF3A_HUMAN
Eukaryotic translation initiation factor 3 subunit A
Search

EIF3A

0.69	Eukaryotic translation initiation factor 3 subunit A

0.71	GO:0006413	translational initiation
0.70	GO:0002181	cytoplasmic translation
0.68	GO:0006446	regulation of translational initiation
0.66	GO:0022618	ribonucleoprotein complex assembly
0.59	GO:0075525	viral translational termination-reinitiation
0.58	GO:0075522	IRES-dependent viral translational initiation
0.40	GO:0070373	negative regulation of ERK1 and ERK2 cascade

0.72	GO:0003743	translation initiation factor activity
0.45	GO:0003729	mRNA binding
0.40	GO:0030971	receptor tyrosine kinase binding
0.34	GO:0005198	structural molecule activity

0.76	GO:0005852	eukaryotic translation initiation factor 3 complex
0.69	GO:0016282	eukaryotic 43S preinitiation complex
0.69	GO:0033290	eukaryotic 48S preinitiation complex
0.50	GO:0005730	nucleolus
0.49	GO:0043614	multi-eIF complex
0.48	GO:0005829	cytosol
0.37	GO:0005874	microtubule
0.35	GO:0005815	microtubule organizing center
0.30	GO:0016020	membrane

sp|Q14153|FA53B_HUMAN
Protein FAM53B
Search

sp|Q14154|DELE_HUMAN
Death ligand signal enhancer
Search

KIAA0141

0.87	Death ligand signal enhancer

0.85	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors
0.82	GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.34	GO:0006468	protein phosphorylation

0.37	GO:0005515	protein binding
0.34	GO:0004672	protein kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.60	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

sp|Q14155|ARHG7_HUMAN
Rho guanine nucleotide exchange factor 7
Search

ARHGEF7

0.89	PAK-interacting exchange factor

0.78	GO:0035023	regulation of Rho protein signal transduction
0.66	GO:0065009	regulation of molecular function
0.61	GO:0035556	intracellular signal transduction
0.55	GO:0060124	positive regulation of growth hormone secretion
0.53	GO:0030032	lamellipodium assembly
0.52	GO:0002244	hematopoietic progenitor cell differentiation
0.52	GO:0007030	Golgi organization
0.50	GO:0043065	positive regulation of apoptotic process
0.37	GO:2000394	positive regulation of lamellipodium morphogenesis
0.37	GO:0010763	positive regulation of fibroblast migration

0.78	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.50	GO:0019901	protein kinase binding

0.51	GO:0043025	neuronal cell body
0.51	GO:0030027	lamellipodium
0.50	GO:0000322	storage vacuole
0.49	GO:0043005	neuron projection
0.45	GO:0005829	cytosol
0.42	GO:0043234	protein complex
0.40	GO:0005886	plasma membrane
0.38	GO:0001726	ruffle
0.37	GO:0005925	focal adhesion
0.37	GO:0005938	cell cortex

sp|Q14156|EFR3A_HUMAN
Protein EFR3 homolog A
Search

EFR3A

0.82	EFR3 homolog A (S. cerevisiae)

0.78	GO:0072659	protein localization to plasma membrane
0.46	GO:0046854	phosphatidylinositol phosphorylation
0.39	GO:0098609	cell-cell adhesion

0.39

GO:0042803

protein homodimerization activity

0.63	GO:0005829	cytosol
0.54	GO:0005886	plasma membrane
0.44	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

sp|Q14157|UBP2L_HUMAN
Ubiquitin-associated protein 2-like
Search

UBAP2L

0.97	Ubiquitin associated protein 2 like

0.86	GO:0061484	hematopoietic stem cell homeostasis
0.78	GO:0007339	binding of sperm to zona pellucida
0.57	GO:0010628	positive regulation of gene expression

0.77	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex
0.75	GO:0031519	PcG protein complex
0.42	GO:0005737	cytoplasm

sp|Q14159|SPIDR_HUMAN
DNA repair-scaffolding protein
Search

sp|Q14160|SCRIB_HUMAN
Protein scribble homolog
Search

0.80	Scribbled planar cell polarity protein

0.84	GO:0071896	protein localization to adherens junction
0.83	GO:0021747	cochlear nucleus development
0.83	GO:0016080	synaptic vesicle targeting
0.82	GO:0035088	establishment or maintenance of apical/basal cell polarity
0.82	GO:0001921	positive regulation of receptor recycling
0.81	GO:0060561	apoptotic process involved in morphogenesis
0.81	GO:0061162	establishment of monopolar cell polarity
0.80	GO:0060088	auditory receptor cell stereocilium organization
0.79	GO:0050918	positive chemotaxis
0.78	GO:0060603	mammary gland duct morphogenesis

0.75	GO:0045296	cadherin binding
0.55	GO:0035255	ionotropic glutamate receptor binding
0.50	GO:0004385	guanylate kinase activity

0.85	GO:0034750	Scrib-APC-beta-catenin complex
0.81	GO:0035748	myelin sheath abaxonal region
0.79	GO:0042734	presynaptic membrane
0.77	GO:0016323	basolateral plasma membrane
0.76	GO:0005913	cell-cell adherens junction
0.76	GO:0044291	cell-cell contact zone
0.76	GO:0045211	postsynaptic membrane
0.73	GO:0031252	cell leading edge
0.64	GO:0005654	nucleoplasm
0.53	GO:0008328	ionotropic glutamate receptor complex

0.50

EC:2.7.4.8

GO:0004385

sp|Q14161|GIT2_HUMAN
ARF GTPase-activating protein GIT2
Search

GIT2

0.84	ARF GTPase-activating protein GIT2

0.76	GO:0043547	positive regulation of GTPase activity
0.37	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway

0.76	GO:0005096	GTPase activator activity
0.49	GO:0046872	metal ion binding
0.35	GO:0005515	protein binding

0.37	GO:0005654	nucleoplasm
0.37	GO:0005925	focal adhesion

sp|Q14162|SREC_HUMAN
Scavenger receptor class F member 1
Search

SCARF1

0.93	Endothelial cells scavenger receptor

0.68	GO:0006898	receptor-mediated endocytosis
0.59	GO:0048680	positive regulation of axon regeneration
0.58	GO:0016322	neuron remodeling
0.56	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.55	GO:0016358	dendrite development
0.38	GO:0006707	cholesterol catabolic process
0.35	GO:0007165	signal transduction
0.34	GO:1903356	positive regulation of distal tip cell migration
0.34	GO:1901076	positive regulation of engulfment of apoptotic cell
0.34	GO:0043654	recognition of apoptotic cell

0.76	GO:0005044	scavenger receptor activity
0.59	GO:0030169	low-density lipoprotein particle binding
0.36	GO:0005509	calcium ion binding
0.36	GO:0004888	transmembrane signaling receptor activity
0.35	GO:0005515	protein binding
0.32	GO:0015179	L-amino acid transmembrane transporter activity

0.38	GO:0030666	endocytic vesicle membrane
0.36	GO:0005925	focal adhesion
0.35	GO:0005886	plasma membrane
0.34	GO:0031143	pseudopodium
0.33	GO:0045335	phagocytic vesicle
0.33	GO:0120038	plasma membrane bounded cell projection part
0.33	GO:0009986	cell surface
0.30	GO:0016021	integral component of membrane

sp|Q14164|IKKE_HUMAN
Inhibitor of nuclear factor kappa-B kinase subunit epsilon
Search

IKBKE

0.92	Inhibitor of nuclear factor kappa-B kinase subunit epsilon

0.63	GO:0006468	protein phosphorylation
0.58	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.57	GO:0034340	response to type I interferon
0.57	GO:0035456	response to interferon-beta
0.57	GO:0010884	positive regulation of lipid storage
0.56	GO:0038061	NIK/NF-kappaB signaling
0.56	GO:0007249	I-kappaB kinase/NF-kappaB signaling
0.56	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage
0.55	GO:0098586	cellular response to virus
0.52	GO:0051260	protein homooligomerization

0.64	GO:0004672	protein kinase activity
0.58	GO:0036435	K48-linked polyubiquitin modification-dependent protein binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0031625	ubiquitin protein ligase binding
0.52	GO:0005057	signal transducer activity, downstream of receptor
0.45	GO:0051219	phosphoprotein binding
0.42	GO:0042802	identical protein binding

0.55	GO:0016605	PML body
0.45	GO:0016235	aggresome
0.45	GO:0031966	mitochondrial membrane
0.36	GO:0010008	endosome membrane
0.35	GO:0005829	cytosol
0.30	GO:0044425	membrane part

sp|Q14165|MLEC_HUMAN
Malectin
Search

MLEC

0.96	Malectin-A

0.36	GO:0005975	carbohydrate metabolic process
0.36	GO:0043312	neutrophil degranulation
0.35	GO:0060271	cilium assembly
0.35	GO:0042953	lipoprotein transport
0.34	GO:0006487	protein N-linked glycosylation
0.34	GO:0016310	phosphorylation
0.34	GO:0006457	protein folding

0.50	GO:0019899	enzyme binding
0.38	GO:0030246	carbohydrate binding
0.36	GO:0005509	calcium ion binding
0.34	GO:0016301	kinase activity
0.34	GO:0008289	lipid binding

0.39	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0035579	specific granule membrane
0.35	GO:0035869	ciliary transition zone
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q14166|TTL12_HUMAN
Tubulin--tyrosine ligase-like protein 12
Search

TTLL12

0.96	Tubulin tyrosine ligase like 12

0.60

GO:0006464

cellular protein modification process

0.54	GO:0016874	ligase activity
0.53	GO:0030554	adenyl nucleotide binding
0.52	GO:0097367	carbohydrate derivative binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0031224

intrinsic component of membrane

0.54

GO:0016874

sp|Q14168|MPP2_HUMAN
MAGUK p55 subfamily member 2
Search

MPP2

0.97	Membrane palmitoylated protein 2

0.76	GO:0060291	long-term synaptic potentiation
0.70	GO:0060079	excitatory postsynaptic potential

0.74

GO:0044325

ion channel binding

0.78	GO:0032590	dendrite membrane
0.76	GO:0043198	dendritic shaft
0.74	GO:0043197	dendritic spine
0.30	GO:0031224	intrinsic component of membrane

sp|Q14181|DPOA2_HUMAN
DNA polymerase alpha subunit B
Search

POLA2

0.75	DNA polymerase alpha subunit B

0.65	GO:0071897	DNA biosynthetic process
0.64	GO:0006260	DNA replication
0.60	GO:0000060	protein import into nucleus, translocation
0.36	GO:0000082	G1/S transition of mitotic cell cycle
0.35	GO:0000723	telomere maintenance
0.34	GO:0019725	cellular homeostasis
0.33	GO:0048193	Golgi vesicle transport
0.33	GO:0043087	regulation of GTPase activity

0.69	GO:0003887	DNA-directed DNA polymerase activity
0.55	GO:0046982	protein heterodimerization activity
0.54	GO:0003677	DNA binding

0.62	GO:0005658	alpha DNA polymerase:primase complex
0.51	GO:0005654	nucleoplasm
0.50	GO:0005829	cytosol
0.35	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.69

EC:2.7.7.7

GO:0003887

sp|Q14183|DOC2A_HUMAN
Double C2-like domain-containing protein alpha
Search

DOC2A

0.96	Double C2 domain alpha

0.84	GO:0017158	regulation of calcium ion-dependent exocytosis
0.77	GO:0007268	chemical synaptic transmission
0.62	GO:0017156	calcium ion regulated exocytosis
0.62	GO:0048489	synaptic vesicle transport
0.62	GO:0099504	synaptic vesicle cycle
0.62	GO:0099643	signal release from synapse
0.60	GO:0031340	positive regulation of vesicle fusion
0.60	GO:1903307	positive regulation of regulated secretory pathway
0.59	GO:0032024	positive regulation of insulin secretion
0.58	GO:0006836	neurotransmitter transport

0.80	GO:0005544	calcium-dependent phospholipid binding
0.69	GO:0005509	calcium ion binding
0.53	GO:0019905	syntaxin binding
0.49	GO:0030276	clathrin binding
0.39	GO:0017137	Rab GTPase binding
0.32	GO:0003676	nucleic acid binding

0.60	GO:0098793	presynapse
0.53	GO:0030054	cell junction
0.52	GO:0005730	nucleolus
0.50	GO:0070382	exocytic vesicle
0.41	GO:0005886	plasma membrane
0.39	GO:0005764	lysosome
0.39	GO:0030658	transport vesicle membrane
0.38	GO:0043005	neuron projection
0.36	GO:0031201	SNARE complex
0.30	GO:0016021	integral component of membrane

sp|Q14184|DOC2B_HUMAN
Double C2-like domain-containing protein beta
Search

DOC2B

0.92	Double C2 domain alpha

0.77	GO:0017158	regulation of calcium ion-dependent exocytosis
0.77	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter
0.76	GO:0031340	positive regulation of vesicle fusion
0.75	GO:1903307	positive regulation of regulated secretory pathway
0.74	GO:0032024	positive regulation of insulin secretion
0.55	GO:0008104	protein localization
0.53	GO:0070727	cellular macromolecule localization
0.51	GO:0042886	amide transport
0.50	GO:0006906	vesicle fusion
0.49	GO:0071702	organic substance transport

0.73	GO:0005544	calcium-dependent phospholipid binding
0.64	GO:0005509	calcium ion binding
0.59	GO:0017137	Rab GTPase binding
0.57	GO:0019905	syntaxin binding
0.50	GO:0030276	clathrin binding
0.34	GO:0070679	inositol 1,4,5 trisphosphate binding
0.34	GO:0008430	selenium binding
0.34	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.34	GO:0042301	phosphate ion binding
0.34	GO:0032403	protein complex binding

0.70	GO:0098793	presynapse
0.51	GO:0070382	exocytic vesicle
0.43	GO:0005886	plasma membrane
0.40	GO:0030054	cell junction
0.39	GO:0005730	nucleolus
0.39	GO:0031201	SNARE complex
0.35	GO:0030658	transport vesicle membrane
0.35	GO:0043005	neuron projection
0.34	GO:0030141	secretory granule
0.34	GO:0005764	lysosome

sp|Q14185|DOCK1_HUMAN
Dedicator of cytokinesis protein 1
Search

DOCK1

0.83	Dedicator of cytokinesis protein 1

0.77	GO:0016477	cell migration
0.76	GO:0007264	small GTPase mediated signal transduction
0.75	GO:0043547	positive regulation of GTPase activity
0.71	GO:0007010	cytoskeleton organization
0.56	GO:0002244	hematopoietic progenitor cell differentiation
0.41	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading
0.41	GO:0010634	positive regulation of epithelial cell migration
0.39	GO:0006909	phagocytosis
0.38	GO:0006915	apoptotic process
0.37	GO:0002431	Fc receptor mediated stimulatory signaling pathway

0.76	GO:0005096	GTPase activator activity
0.75	GO:0005085	guanyl-nucleotide exchange factor activity
0.38	GO:0017124	SH3 domain binding
0.36	GO:0017048	Rho GTPase binding
0.34	GO:0020037	heme binding

0.55	GO:0016607	nuclear speck
0.49	GO:0005829	cytosol
0.41	GO:0032045	guanyl-nucleotide exchange factor complex
0.30	GO:0016020	membrane

sp|Q14186|TFDP1_HUMAN
Transcription factor Dp-1
Search

TFDP1

0.91	LOW QUALITY PROTEIN: transcription factor Dp-1

0.66	GO:0007049	cell cycle
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0070345	negative regulation of fat cell proliferation
0.53	GO:0043276	anoikis
0.50	GO:1902680	positive regulation of RNA biosynthetic process
0.49	GO:0008544	epidermis development
0.46	GO:0051052	regulation of DNA metabolic process

0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0003677	DNA binding
0.46	GO:0008134	transcription factor binding
0.45	GO:0019904	protein domain specific binding
0.45	GO:0001067	regulatory region nucleic acid binding
0.43	GO:0003712	transcription cofactor activity
0.37	GO:0015299	solute:proton antiporter activity

0.74	GO:0005667	transcription factor complex
0.60	GO:0005634	nucleus
0.41	GO:0031974	membrane-enclosed lumen
0.40	GO:0005829	cytosol
0.40	GO:0044446	intracellular organelle part
0.33	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

sp|Q14188|TFDP2_HUMAN
Transcription factor Dp-2
Search

TFDP2

0.97	Transcription factor Dp-2

0.70	GO:0000278	mitotic cell cycle
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.51	GO:1902680	positive regulation of RNA biosynthetic process
0.48	GO:1902679	negative regulation of RNA biosynthetic process
0.42	GO:0070345	negative regulation of fat cell proliferation
0.41	GO:0043276	anoikis
0.40	GO:0008544	epidermis development

0.71	GO:0003712	transcription cofactor activity
0.69	GO:0008134	transcription factor binding
0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0003677	DNA binding
0.51	GO:0019904	protein domain specific binding
0.51	GO:0001067	regulatory region nucleic acid binding
0.33	GO:0015299	solute:proton antiporter activity

0.74	GO:0005667	transcription factor complex
0.60	GO:0005634	nucleus
0.43	GO:0044446	intracellular organelle part
0.37	GO:0043233	organelle lumen
0.36	GO:0005829	cytosol
0.33	GO:0012505	endomembrane system
0.33	GO:0005739	mitochondrion
0.33	GO:0031975	envelope
0.30	GO:0031224	intrinsic component of membrane

sp|Q14190|SIM2_HUMAN
Single-minded homolog 2
Search

SIM2

0.95	Single-minded like protein 2

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0035295	tube development
0.54	GO:0048731	system development
0.53	GO:0009880	embryonic pattern specification
0.48	GO:0051253	negative regulation of RNA metabolic process
0.48	GO:0010558	negative regulation of macromolecule biosynthetic process
0.48	GO:0031327	negative regulation of cellular biosynthetic process

0.65	GO:0046983	protein dimerization activity
0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding

0.61	GO:0005634	nucleus
0.46	GO:0031974	membrane-enclosed lumen
0.42	GO:0044446	intracellular organelle part
0.41	GO:0005667	transcription factor complex
0.35	GO:0005737	cytoplasm

sp|Q14191|WRN_HUMAN
Werner syndrome ATP-dependent helicase
Search

WRN

0.93	Werner syndrome ATP-dependent helicase

0.70	GO:0032392	DNA geometric change
0.66	GO:0006260	DNA replication
0.65	GO:0006310	DNA recombination
0.65	GO:0006281	DNA repair
0.63	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.58	GO:0098530	positive regulation of strand invasion
0.56	GO:0040009	regulation of growth rate
0.56	GO:1902570	protein localization to nucleolus
0.56	GO:0061820	telomeric D-loop disassembly
0.55	GO:0010225	response to UV-C

0.80	GO:0043140	ATP-dependent 3'-5' DNA helicase activity
0.71	GO:0008408	3'-5' exonuclease activity
0.57	GO:0070337	3'-flap-structured DNA binding
0.57	GO:0061749	forked DNA-dependent helicase activity
0.57	GO:1905773	8-hydroxy-2'-deoxyguanosine DNA binding
0.57	GO:0061821	telomeric D-loop binding
0.55	GO:0000405	bubble DNA binding
0.55	GO:0051880	G-quadruplex DNA binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0000403	Y-form DNA binding

0.54	GO:0032389	MutLalpha complex
0.52	GO:0000781	chromosome, telomeric region
0.51	GO:0016607	nuclear speck
0.50	GO:0005813	centrosome
0.49	GO:0005657	replication fork
0.49	GO:0005730	nucleolus
0.39	GO:0043005	neuron projection
0.36	GO:0005737	cytoplasm

sp|Q14192|FHL2_HUMAN
Four and a half LIM domains protein 2
Search

FHL2

0.92	Four and a half LIM domains protein 2

0.57	GO:0055014	atrial cardiac muscle cell development
0.55	GO:0055015	ventricular cardiac muscle cell development
0.55	GO:0060347	heart trabecula formation
0.53	GO:0001649	osteoblast differentiation
0.50	GO:0043066	negative regulation of apoptotic process
0.50	GO:0000122	negative regulation of transcription by RNA polymerase II
0.49	GO:0009725	response to hormone
0.35	GO:0006351	transcription, DNA-templated
0.35	GO:0030522	intracellular receptor signaling pathway
0.35	GO:0019216	regulation of lipid metabolic process

0.54	GO:0046872	metal ion binding
0.48	GO:0042802	identical protein binding
0.48	GO:0008134	transcription factor binding
0.35	GO:0051427	hormone receptor binding
0.35	GO:0003713	transcription coactivator activity
0.34	GO:0003779	actin binding
0.34	GO:0004707	MAP kinase activity
0.32	GO:0005524	ATP binding

0.43	GO:0005634	nucleus
0.42	GO:0031430	M band
0.41	GO:0030018	Z disc
0.37	GO:0005925	focal adhesion
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part

0.34	EC:2.7.11.24	GO:0004707
0.34	KEGG:R00162	GO:0004707

sp|Q14194|DPYL1_HUMAN
Dihydropyrimidinase-related protein 1
Search

CRMP1

0.96	Dihydropyrimidinase-related protein 1 isoform B

0.79	GO:0007411	axon guidance
0.75	GO:0000226	microtubule cytoskeleton organization
0.47	GO:0010975	regulation of neuron projection development
0.45	GO:0051491	positive regulation of filopodium assembly
0.45	GO:0048678	response to axon injury
0.44	GO:0051017	actin filament bundle assembly
0.43	GO:1904617	negative regulation of actin binding
0.43	GO:1904529	regulation of actin filament binding
0.42	GO:0030334	regulation of cell migration
0.42	GO:0045665	negative regulation of neuron differentiation

0.65	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
0.43	GO:0031005	filamin binding
0.40	GO:0051219	phosphoprotein binding

0.48	GO:0005737	cytoplasm
0.42	GO:0005813	centrosome
0.42	GO:0030496	midbody
0.40	GO:0005819	spindle
0.40	GO:0031941	filamentous actin
0.40	GO:0030426	growth cone
0.39	GO:0043025	neuronal cell body
0.39	GO:0030425	dendrite

0.65

EC:3.5

GO:0016810

sp|Q14195|DPYL3_HUMAN
Dihydropyrimidinase-related protein 3
Search

DPYSL3

0.97	Testicular secretory protein Li 7

0.85	GO:0051491	positive regulation of filopodium assembly
0.85	GO:0048678	response to axon injury
0.82	GO:0051017	actin filament bundle assembly
0.81	GO:0010975	regulation of neuron projection development
0.78	GO:0030334	regulation of cell migration
0.48	GO:0051764	actin crosslink formation
0.47	GO:0048666	neuron development
0.46	GO:0045665	negative regulation of neuron differentiation
0.46	GO:0031345	negative regulation of cell projection organization
0.46	GO:0120039	plasma membrane bounded cell projection morphogenesis

0.65	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
0.55	GO:0031005	filamin binding
0.49	GO:0035374	chondroitin sulfate binding
0.45	GO:0017124	SH3 domain binding
0.39	GO:0008017	microtubule binding
0.36	GO:0051219	phosphoprotein binding
0.36	GO:0019901	protein kinase binding
0.36	GO:0042802	identical protein binding

0.49	GO:0030426	growth cone
0.48	GO:0005737	cytoplasm
0.47	GO:0031941	filamentous actin
0.47	GO:0044297	cell body
0.46	GO:0030027	lamellipodium
0.44	GO:0005615	extracellular space
0.44	GO:0031982	vesicle
0.42	GO:0012505	endomembrane system
0.37	GO:0043209	myelin sheath
0.37	GO:0030425	dendrite

0.65

EC:3.5

GO:0016810

sp|Q14197|ICT1_HUMAN
Peptidyl-tRNA hydrolase ICT1, mitochondrial
Search

MRPL58

0.54	Peptide chain release factor I

0.74	GO:0006415	translational termination
0.57	GO:0032543	mitochondrial translation
0.51	GO:0072344	rescue of stalled ribosome
0.33	GO:0007165	signal transduction
0.33	GO:0034220	ion transmembrane transport

0.75	GO:0003747	translation release factor activity
0.56	GO:0004045	aminoacyl-tRNA hydrolase activity
0.34	GO:0005230	extracellular ligand-gated ion channel activity
0.33	GO:0004888	transmembrane signaling receptor activity

0.60	GO:0005762	mitochondrial large ribosomal subunit
0.35	GO:0031966	mitochondrial membrane
0.35	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

0.56

EC:3.1.1.29

GO:0004045

sp|Q14201|BTG3_HUMAN
Protein BTG3
Search

BTG3

0.94	BTG anti-proliferation factor 3

0.69	GO:0008285	negative regulation of cell proliferation
0.64	GO:0045930	negative regulation of mitotic cell cycle
0.36	GO:0006979	response to oxidative stress
0.34	GO:0071805	potassium ion transmembrane transport

0.38	GO:0005515	protein binding
0.34	GO:0016286	small conductance calcium-activated potassium channel activity

0.42	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

sp|Q14202|ZMYM3_HUMAN
Zinc finger MYM-type protein 3
Search

ZMYM3

0.95	Zinc finger MYM-type containing 3

0.52	GO:0007010	cytoskeleton organization
0.51	GO:0022604	regulation of cell morphogenesis
0.45	GO:0006357	regulation of transcription by RNA polymerase II
0.44	GO:0007275	multicellular organism development
0.33	GO:0016233	telomere capping
0.33	GO:1902653	secondary alcohol biosynthetic process
0.33	GO:0016126	sterol biosynthetic process
0.33	GO:0034754	cellular hormone metabolic process
0.33	GO:0042446	hormone biosynthetic process
0.32	GO:0042181	ketone biosynthetic process

0.62	GO:0008270	zinc ion binding
0.45	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.39	GO:0003677	DNA binding
0.34	GO:0005515	protein binding
0.33	GO:0003682	chromatin binding

0.52	GO:0005654	nucleoplasm
0.37	GO:0005737	cytoplasm
0.33	GO:0035012	polytene chromosome, telomeric region
0.33	GO:0005705	polytene chromosome interband
0.33	GO:0000791	euchromatin
0.33	GO:0000792	heterochromatin
0.32	GO:0043234	protein complex

sp|Q14203|DCTN1_HUMAN
Dynactin subunit 1
Search

DCTN1

0.86	Dynactin subunit 1

0.81	GO:0010970	transport along microtubule
0.55	GO:0090063	positive regulation of microtubule nucleation
0.54	GO:0051081	nuclear envelope disassembly
0.53	GO:0010457	centriole-centriole cohesion
0.53	GO:0032402	melanosome transport
0.53	GO:0034454	microtubule anchoring at centrosome
0.53	GO:0000132	establishment of mitotic spindle orientation
0.52	GO:0060236	regulation of mitotic spindle organization
0.52	GO:1905515	non-motile cilium assembly
0.50	GO:0042147	retrograde transport, endosome to Golgi

0.84	GO:0070840	dynein complex binding
0.49	GO:0019901	protein kinase binding
0.48	GO:0008017	microtubule binding
0.38	GO:0003774	motor activity
0.34	GO:0042802	identical protein binding

0.81	GO:0005869	dynactin complex
0.54	GO:0120103	centriolar subdistal appendage
0.53	GO:0035371	microtubule plus-end
0.52	GO:0099738	cell cortex region
0.52	GO:0005814	centriole
0.51	GO:0030904	retromer complex
0.50	GO:0005813	centrosome
0.50	GO:0031252	cell leading edge
0.50	GO:0000776	kinetochore
0.50	GO:0000922	spindle pole

sp|Q14204|DYHC1_HUMAN
Cytoplasmic dynein 1 heavy chain 1
Search

DYNC1H1

0.85	Dynein heavy chain, cytoplasmic

0.72	GO:0007018	microtubule-based movement
0.53	GO:1905832	positive regulation of spindle assembly
0.52	GO:0090235	regulation of metaphase plate congression
0.51	GO:0033962	cytoplasmic mRNA processing body assembly
0.51	GO:0034063	stress granule assembly
0.50	GO:0060236	regulation of mitotic spindle organization
0.50	GO:0051293	establishment of spindle localization
0.49	GO:0032388	positive regulation of intracellular transport
0.47	GO:0099518	vesicle cytoskeletal trafficking
0.47	GO:0031122	cytoplasmic microtubule organization

0.72	GO:0003777	microtubule motor activity
0.59	GO:0016887	ATPase activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0051959	dynein light intermediate chain binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0045503	dynein light chain binding
0.47	GO:0045505	dynein intermediate chain binding
0.34	GO:0003723	RNA binding

0.74	GO:0030286	dynein complex
0.50	GO:0030175	filopodium
0.48	GO:0005813	centrosome
0.46	GO:0005874	microtubule
0.38	GO:0031012	extracellular matrix
0.37	GO:0070062	extracellular exosome
0.37	GO:0005737	cytoplasm
0.36	GO:0002177	manchette
0.36	GO:0031983	vesicle lumen
0.36	GO:0012505	endomembrane system

0.59

GO:0016887

sp|Q14206|RCAN2_HUMAN
Calcipressin-2
Search

RCAN2

0.97	Calcineurin inhibitory protein ZAKI-4 beta

0.84	GO:0019722	calcium-mediated signaling
0.51	GO:0070884	regulation of calcineurin-NFAT signaling cascade
0.47	GO:0043666	regulation of phosphoprotein phosphatase activity
0.37	GO:0031987	locomotion involved in locomotory behavior
0.37	GO:0007614	short-term memory
0.36	GO:0048016	inositol phosphate-mediated signaling
0.36	GO:0007219	Notch signaling pathway
0.35	GO:0006979	response to oxidative stress
0.35	GO:1903830	magnesium ion transmembrane transport
0.33	GO:0009653	anatomical structure morphogenesis

0.53	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity
0.51	GO:0003676	nucleic acid binding
0.48	GO:0031013	troponin I binding
0.35	GO:0015095	magnesium ion transmembrane transporter activity

0.45	GO:0005622	intracellular
0.30	GO:0031224	intrinsic component of membrane

sp|Q14207|NPAT_HUMAN
Protein NPAT
Search

NPAT

0.97	Nuclear protein, coactivator of histone transcription

0.85	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle
0.73	GO:0045893	positive regulation of transcription, DNA-templated
0.72	GO:1903507	negative regulation of nucleic acid-templated transcription

0.85	GO:0047485	protein N-terminus binding
0.83	GO:0008022	protein C-terminus binding
0.81	GO:0003714	transcription corepressor activity
0.79	GO:0003713	transcription coactivator activity

0.86	GO:0097504	Gemini of coiled bodies
0.85	GO:0015030	Cajal body
0.49	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q14209|E2F2_HUMAN
Transcription factor E2F2
Search

E2F2

0.90	Transcription factor E2F2 isoform A

0.65	GO:1990086	lens fiber cell apoptotic process
0.63	GO:1903671	negative regulation of sprouting angiogenesis
0.61	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:0045944	positive regulation of transcription by RNA polymerase II
0.54	GO:0051726	regulation of cell cycle
0.41	GO:0070345	negative regulation of fat cell proliferation
0.41	GO:1905461	positive regulation of vascular associated smooth muscle cell apoptotic process
0.39	GO:0008284	positive regulation of cell proliferation
0.36	GO:0007049	cell cycle

0.68	GO:0046983	protein dimerization activity
0.61	GO:0001047	core promoter binding
0.61	GO:0003700	DNA binding transcription factor activity
0.58	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.54	GO:0008134	transcription factor binding
0.35	GO:0051539	4 iron, 4 sulfur cluster binding
0.34	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
0.33	GO:0016740	transferase activity

0.74	GO:0005667	transcription factor complex
0.61	GO:0005634	nucleus
0.46	GO:0044446	intracellular organelle part
0.35	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0016616

sp|Q14210|LY6D_HUMAN
Lymphocyte antigen 6D
Search

LY6D

0.97	Lymphocyte antigen 6 family member D

0.83	GO:0035634	response to stilbenoid
0.75	GO:0030098	lymphocyte differentiation
0.45	GO:0006501	C-terminal protein lipidation
0.41	GO:0007155	cell adhesion

0.34

GO:0005515

protein binding

0.69	GO:0009986	cell surface
0.49	GO:0031225	anchored component of membrane
0.40	GO:0005886	plasma membrane
0.39	GO:0005576	extracellular region
0.35	GO:0098552	side of membrane
0.32	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|Q14213|IL27B_HUMAN
Interleukin-27 subunit beta
Search

EBI3

0.96	Epstein-Barr virus induced gene 3

0.80	GO:0019221	cytokine-mediated signaling pathway
0.53	GO:0042098	T cell proliferation

0.81	GO:0004896	cytokine receptor activity
0.56	GO:0045523	interleukin-27 receptor binding

0.30

GO:0016020

membrane

sp|Q14232|EI2BA_HUMAN
Translation initiation factor eIF-2B subunit alpha
Search

EIF2B1

0.89	LOW QUALITY PROTEIN: translation initiation factor eIF-2B subunit alpha

0.64	GO:0006413	translational initiation
0.59	GO:1904628	cellular response to phorbol 13-acetate 12-myristate
0.57	GO:0014003	oligodendrocyte development
0.47	GO:0065009	regulation of molecular function
0.37	GO:0009749	response to glucose
0.36	GO:0043434	response to peptide hormone
0.36	GO:1990928	response to amino acid starvation
0.36	GO:0009408	response to heat
0.33	GO:0048519	negative regulation of biological process

0.65	GO:0003743	translation initiation factor activity
0.52	GO:0005085	guanyl-nucleotide exchange factor activity
0.50	GO:0042802	identical protein binding
0.35	GO:0019003	GDP binding
0.33	GO:0005525	GTP binding

0.57	GO:0005851	eukaryotic translation initiation factor 2B complex
0.42	GO:0005886	plasma membrane
0.35	GO:0005850	eukaryotic translation initiation factor 2 complex
0.34	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

sp|Q14236|EPAG_HUMAN
Early lymphoid activation gene protein
Search

0.37	Early lymphoid activation gene protein

0.61

GO:0007165

signal transduction

0.64

GO:0004871

signal transducer activity

sp|Q14240|IF4A2_HUMAN
Eukaryotic initiation factor 4A-II
Search

EIF4A2

0.65	Eukaryotic initiation factor 4A-III

0.72	GO:0006413	translational initiation
0.56	GO:1900260	negative regulation of RNA-directed 5'-3' RNA polymerase activity
0.52	GO:1990823	response to leukemia inhibitory factor
0.49	GO:0071345	cellular response to cytokine stimulus
0.46	GO:0010501	RNA secondary structure unwinding
0.38	GO:0010468	regulation of gene expression
0.35	GO:0016926	protein desumoylation
0.34	GO:0006401	RNA catabolic process
0.34	GO:0034248	regulation of cellular amide metabolic process
0.33	GO:0016071	mRNA metabolic process

0.78	GO:0004004	ATP-dependent RNA helicase activity
0.72	GO:0003743	translation initiation factor activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0003725	double-stranded RNA binding
0.33	GO:0008234	cysteine-type peptidase activity
0.33	GO:0005515	protein binding

0.49	GO:0048471	perinuclear region of cytoplasm
0.43	GO:0005730	nucleolus
0.35	GO:0016281	eukaryotic translation initiation factor 4F complex
0.34	GO:0071339	MLL1 complex
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0008234

sp|Q14241|ELOA1_HUMAN
Elongin-A
Search

ELOA

0.92	transcription elongation factor B polypeptide 3

0.70	GO:0006357	regulation of transcription by RNA polymerase II
0.57	GO:0006414	translational elongation
0.49	GO:0006368	transcription elongation from RNA polymerase II promoter

0.58	GO:0003746	translation elongation factor activity
0.38	GO:0003735	structural constituent of ribosome
0.35	GO:0003690	double-stranded DNA binding
0.34	GO:0005515	protein binding
0.33	GO:0016787	hydrolase activity

0.85	GO:0070449	elongin complex
0.37	GO:0005840	ribosome
0.37	GO:0005615	extracellular space

0.33

GO:0016787

sp|Q14242|SELPL_HUMAN
P-selectin glycoprotein ligand 1
Search

SELPLG

0.97	p-selectin glycoprotein ligand

0.67	GO:0050901	leukocyte tethering or rolling
0.65	GO:0071354	cellular response to interleukin-6
0.50	GO:0050902	leukocyte adhesive activation
0.38	GO:0030260	entry into host cell
0.38	GO:0019058	viral life cycle

0.55	GO:0030246	carbohydrate binding
0.43	GO:0104005	hijacked molecular function
0.40	GO:0005515	protein binding

0.67	GO:0001931	uropod
0.63	GO:0044853	plasma membrane raft
0.38	GO:0005887	integral component of plasma membrane

sp|Q14244|MAP7_HUMAN
Ensconsin
Search

MAP7

0.96	Microtubule associated protein 7

0.76	GO:0000226	microtubule cytoskeleton organization
0.39	GO:0033327	Leydig cell differentiation
0.39	GO:0060009	Sertoli cell development
0.38	GO:0032526	response to retinoic acid
0.38	GO:0035265	organ growth
0.38	GO:0006687	glycosphingolipid metabolic process
0.38	GO:0072659	protein localization to plasma membrane
0.38	GO:0009566	fertilization
0.38	GO:0006997	nucleus organization
0.37	GO:0007283	spermatogenesis

0.40	GO:0005198	structural molecule activity
0.36	GO:0005102	receptor binding
0.34	GO:0004709	MAP kinase kinase kinase activity
0.34	GO:0019903	protein phosphatase binding
0.34	GO:0019901	protein kinase binding
0.34	GO:0019904	protein domain specific binding
0.34	GO:0042803	protein homodimerization activity
0.33	GO:0003723	RNA binding
0.33	GO:0000287	magnesium ion binding
0.32	GO:0030554	adenyl nucleotide binding

0.71	GO:0015630	microtubule cytoskeleton
0.47	GO:0005829	cytosol
0.36	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0016323	basolateral plasma membrane
0.36	GO:0099513	polymeric cytoskeletal fiber
0.35	GO:1990604	IRE1-TRAF2-ASK1 complex
0.34	GO:1902911	protein kinase complex

0.34

EC:2.7.11 EC:2.7.11.25

GO:0004709

sp|Q14246|AGRE1_HUMAN
Adhesion G protein-coupled receptor E1
Search

ADGRE1

0.83	Adhesion G protein-coupled receptor E1

0.71	GO:0007166	cell surface receptor signaling pathway
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.47	GO:0002376	immune system process
0.46	GO:0007155	cell adhesion
0.45	GO:0060326	cell chemotaxis
0.44	GO:0043304	regulation of mast cell degranulation
0.41	GO:0006954	inflammatory response
0.37	GO:0045055	regulated exocytosis
0.36	GO:0001775	cell activation

0.72	GO:0004930	G-protein coupled receptor activity
0.67	GO:0005509	calcium ion binding
0.48	GO:0035374	chondroitin sulfate binding

0.47	GO:0009897	external side of plasma membrane
0.46	GO:0031256	leading edge membrane
0.41	GO:0001726	ruffle
0.41	GO:0031253	cell projection membrane
0.39	GO:0005887	integral component of plasma membrane
0.38	GO:0101003	ficolin-1-rich granule membrane
0.35	GO:0005576	extracellular region

sp|Q14247|SRC8_HUMAN
Src substrate cortactin
Search

CTTN

0.54	src substrate cortactin

0.84	GO:0030041	actin filament polymerization
0.59	GO:0097062	dendritic spine maintenance
0.58	GO:0006930	substrate-dependent cell migration, cell extension
0.57	GO:0045987	positive regulation of smooth muscle contraction
0.56	GO:1903146	regulation of autophagy of mitochondrion
0.55	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway
0.53	GO:0030838	positive regulation of actin filament polymerization
0.48	GO:0006886	intracellular protein transport
0.30	GO:0034332	adherens junction organization
0.30	GO:0007160	cell-matrix adhesion

0.58	GO:0005522	profilin binding
0.53	GO:0045296	cadherin binding

0.56	GO:0002102	podosome
0.55	GO:1990023	mitotic spindle midzone
0.54	GO:0001726	ruffle
0.54	GO:0005884	actin filament
0.54	GO:0030027	lamellipodium
0.53	GO:0030863	cortical cytoskeleton
0.52	GO:0008076	voltage-gated potassium channel complex
0.49	GO:0005794	Golgi apparatus
0.48	GO:0005829	cytosol
0.38	GO:0030136	clathrin-coated vesicle

sp|Q14249|NUCG_HUMAN
Endonuclease G, mitochondrial
Search

ENDOG

0.62	Mitochondrial endonuclease G

0.61	GO:0006309	apoptotic DNA fragmentation
0.57	GO:0034612	response to tumor necrosis factor
0.54	GO:0001701	in utero embryonic development
0.54	GO:0043065	positive regulation of apoptotic process
0.52	GO:0046677	response to antibiotic
0.45	GO:0036475	neuron death in response to oxidative stress
0.44	GO:1903626	positive regulation of DNA catabolic process
0.43	GO:1902510	regulation of apoptotic DNA fragmentation
0.43	GO:1901300	positive regulation of hydrogen peroxide-mediated programmed cell death
0.42	GO:0032355	response to estradiol

0.54	GO:0046872	metal ion binding
0.54	GO:0004519	endonuclease activity
0.51	GO:0003676	nucleic acid binding
0.39	GO:0004536	deoxyribonuclease activity
0.36	GO:0044540	L-cystine L-cysteine-lyase (deaminating)
0.36	GO:0080146	L-cysteine desulfhydrase activity
0.36	GO:0004123	cystathionine gamma-lyase activity
0.34	GO:0005515	protein binding
0.33	GO:0004540	ribonuclease activity

0.45	GO:0005739	mitochondrion
0.42	GO:0043204	perikaryon
0.38	GO:0005829	cytosol
0.37	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.36	EC:4.4.1.1	GO:0044540
0.36	KEGG:R02408	GO:0044540

sp|Q14254|FLOT2_HUMAN
Flotillin-2
Search

FLOT2

0.90	Dehydrogenase/reductase 13

0.84	GO:0044860	protein localization to plasma membrane raft
0.82	GO:1902992	negative regulation of amyloid precursor protein catabolic process
0.81	GO:0045661	regulation of myoblast differentiation
0.78	GO:0001765	membrane raft assembly
0.75	GO:0072659	protein localization to plasma membrane
0.72	GO:0050821	protein stabilization
0.70	GO:1903905	positive regulation of establishment of T cell polarity
0.62	GO:0010629	negative regulation of gene expression
0.50	GO:0007155	cell adhesion
0.48	GO:0034139	regulation of toll-like receptor 3 signaling pathway

0.67	GO:0046982	protein heterodimerization activity
0.54	GO:0035255	ionotropic glutamate receptor binding
0.52	GO:0002020	protease binding
0.36	GO:0046872	metal ion binding

0.84	GO:0016600	flotillin complex
0.82	GO:0002080	acrosomal membrane
0.81	GO:0001931	uropod
0.77	GO:0044291	cell-cell contact zone
0.76	GO:0030139	endocytic vesicle
0.75	GO:0005913	cell-cell adherens junction
0.75	GO:0030027	lamellipodium
0.74	GO:0016323	basolateral plasma membrane
0.73	GO:0030864	cortical actin cytoskeleton
0.72	GO:0048471	perinuclear region of cytoplasm

sp|Q14257|RCN2_HUMAN
Reticulocalbin-2
Search

RCN2

0.92	Reticulocalbin 2, EF-hand calcium binding domain

0.70	GO:0005509	calcium ion binding
0.35	GO:0005515	protein binding

0.54	GO:0005730	nucleolus
0.53	GO:0005783	endoplasmic reticulum
0.34	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

sp|Q14258|TRI25_HUMAN
E3 ubiquitin/ISG15 ligase TRIM25
Search

TRIM25

0.96	Tripartite motif-containing protein 25

0.67	GO:0046597	negative regulation of viral entry into host cell
0.66	GO:1902187	negative regulation of viral release from host cell
0.65	GO:0043627	response to estrogen
0.64	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.64	GO:0006513	protein monoubiquitination
0.64	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.64	GO:1990830	cellular response to leukemia inhibitory factor
0.63	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.63	GO:0030433	ubiquitin-dependent ERAD pathway
0.61	GO:0045087	innate immune response

0.68	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway
0.62	GO:0045296	cadherin binding
0.57	GO:0008270	zinc ion binding
0.47	GO:0016874	ligase activity
0.35	GO:0003723	RNA binding
0.34	GO:0003700	DNA binding transcription factor activity

0.60	GO:0016604	nuclear body
0.54	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.47

GO:0016874

sp|Q14264|ENR1_HUMAN
Endogenous retrovirus group 3 member 1 Env polyprotein
Search

0.87	Endogenous retrovirus group 3, member 1

0.66	GO:0070062	extracellular exosome
0.65	GO:0036338	viral membrane
0.30	GO:0016020	membrane

sp|Q14289|FAK2_HUMAN
Protein-tyrosine kinase 2-beta
Search

PTK2B

0.96	Proline-rich tyrosine kinase 2

0.85	GO:2000249	regulation of actin cytoskeleton reorganization
0.85	GO:0007172	signal complex assembly
0.84	GO:0030500	regulation of bone mineralization
0.84	GO:0002688	regulation of leukocyte chemotaxis
0.81	GO:0045765	regulation of angiogenesis
0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.76	GO:0042127	regulation of cell proliferation
0.75	GO:0030155	regulation of cell adhesion
0.63	GO:0010752	regulation of cGMP-mediated signaling
0.63	GO:0032960	regulation of inositol trisphosphate biosynthetic process

0.80	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.63	GO:0004871	signal transducer activity
0.59	GO:0008022	protein C-terminus binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0032555	purine ribonucleotide binding
0.46	GO:0005102	receptor binding
0.45	GO:0043423	3-phosphoinositide-dependent protein kinase binding
0.42	GO:0004683	calmodulin-dependent protein kinase activity

0.80	GO:0005925	focal adhesion
0.79	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.68	GO:0005856	cytoskeleton
0.59	GO:0030027	lamellipodium
0.57	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0005634	nucleus
0.43	GO:0097440	apical dendrite
0.43	GO:0017146	NMDA selective glutamate receptor complex
0.42	GO:0043197	dendritic spine
0.42	GO:0030426	growth cone

0.80

GO:0004715

sp|Q14296|FASTK_HUMAN
Fas-activated serine/threonine kinase
Search

FASTK

0.97	Fas-activated serine/threonine kinase

0.63	GO:0006468	protein phosphorylation
0.55	GO:0043484	regulation of RNA splicing
0.37	GO:0006915	apoptotic process
0.34	GO:0007165	signal transduction

0.64	GO:0004672	protein kinase activity
0.35	GO:0003723	RNA binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0005515	protein binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.37	GO:0005759	mitochondrial matrix
0.37	GO:0016607	nuclear speck

sp|Q14314|FGL2_HUMAN
Fibroleukin
Search

FGL2

0.97	Fibroleukin

0.60	GO:0006508	proteolysis
0.39	GO:0007567	parturition
0.37	GO:0010952	positive regulation of peptidase activity
0.36	GO:0043312	neutrophil degranulation
0.35	GO:0019835	cytolysis
0.34	GO:0009405	pathogenesis

0.61	GO:0008233	peptidase activity
0.38	GO:0016504	peptidase activator activity
0.34	GO:0090729	toxin activity

0.39	GO:0070062	extracellular exosome
0.37	GO:1904813	ficolin-1-rich granule lumen
0.36	GO:0009986	cell surface
0.36	GO:0005577	fibrinogen complex
0.30	GO:0031224	intrinsic component of membrane

0.61

GO:0008233

sp|Q14315|FLNC_HUMAN
Filamin-C
Search

FLNC

0.59	Filamin C, gamma a (actin binding protein 280)

0.53	GO:0048747	muscle fiber development
0.46	GO:0046716	muscle cell cellular homeostasis
0.45	GO:0007626	locomotory behavior
0.36	GO:0030036	actin cytoskeleton organization
0.30	GO:0034330	cell junction organization
0.30	GO:0044085	cellular component biogenesis

0.74	GO:0003779	actin binding
0.71	GO:0032403	protein complex binding
0.55	GO:0030506	ankyrin binding
0.36	GO:0042802	identical protein binding

0.53	GO:0042383	sarcolemma
0.46	GO:0005829	cytosol
0.38	GO:0043034	costamere
0.37	GO:0016528	sarcoplasm
0.37	GO:0030018	Z disc
0.37	GO:0005925	focal adhesion
0.35	GO:0005856	cytoskeleton
0.30	GO:0031224	intrinsic component of membrane

sp|Q14318|FKBP8_HUMAN
Peptidyl-prolyl cis-trans isomerase FKBP8
Search

FKBP8

0.46	Peptidyl-prolyl cis-trans isomerase FKBP8

0.80	GO:0021904	dorsal/ventral neural tube patterning
0.78	GO:0030513	positive regulation of BMP signaling pathway
0.76	GO:0035264	multicellular organism growth
0.76	GO:0001708	cell fate specification
0.75	GO:0007224	smoothened signaling pathway
0.73	GO:0043010	camera-type eye development
0.71	GO:0061077	chaperone-mediated protein folding
0.70	GO:0043066	negative regulation of apoptotic process
0.70	GO:0006915	apoptotic process
0.68	GO:0001933	negative regulation of protein phosphorylation

0.78	GO:0097718	disordered domain specific binding
0.77	GO:0005528	FK506 binding
0.67	GO:0042802	identical protein binding
0.65	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.42	GO:0046872	metal ion binding

0.70	GO:0030176	integral component of endoplasmic reticulum membrane
0.64	GO:0005829	cytosol
0.57	GO:0005739	mitochondrion
0.56	GO:0031967	organelle envelope
0.56	GO:0031090	organelle membrane
0.55	GO:0043234	protein complex

0.65

GO:0003755

sp|Q14320|FA50A_HUMAN
Protein FAM50A
Search

FAM50A

0.92	XAP-5 protein (Predicted)

0.36	GO:0071526	semaphorin-plexin signaling pathway
0.35	GO:0007264	small GTPase mediated signal transduction
0.35	GO:0043547	positive regulation of GTPase activity
0.34	GO:0007283	spermatogenesis
0.34	GO:0015031	protein transport
0.32	GO:0016310	phosphorylation

0.36	GO:0005093	Rab GDP-dissociation inhibitor activity
0.36	GO:0017154	semaphorin receptor activity
0.35	GO:0005096	GTPase activator activity
0.34	GO:0003723	RNA binding
0.33	GO:0005515	protein binding
0.32	GO:0016301	kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005634	nucleus
0.48	GO:0031974	membrane-enclosed lumen
0.48	GO:0045171	intercellular bridge
0.43	GO:0044446	intracellular organelle part
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q14324|MYPC2_HUMAN
Myosin-binding protein C, fast-type
Search

MYBPC2

0.94	Myosin-binding protein C, cardiac-type

0.77	GO:0006936	muscle contraction
0.69	GO:0071688	striated muscle myosin thick filament assembly
0.66	GO:0045214	sarcomere organization
0.59	GO:0007015	actin filament organization
0.55	GO:0060537	muscle tissue development
0.49	GO:0003210	cardiac atrium formation
0.47	GO:0003211	cardiac ventricle formation
0.46	GO:0060415	muscle tissue morphogenesis
0.46	GO:0002027	regulation of heart rate
0.43	GO:0007155	cell adhesion

0.70	GO:0097493	structural molecule activity conferring elasticity
0.69	GO:0051371	muscle alpha-actinin binding
0.68	GO:0008307	structural constituent of muscle
0.61	GO:0051015	actin filament binding
0.39	GO:0005200	structural constituent of cytoskeleton

0.69	GO:0005859	muscle myosin complex
0.67	GO:0031430	M band
0.65	GO:0030018	Z disc
0.48	GO:0032982	myosin filament
0.38	GO:0005829	cytosol

sp|Q14330|GPR18_HUMAN
N-arachidonyl glycine receptor
Search

GPR18

0.97	N-arachidonyl glycine receptor

0.69	GO:0007186	G-protein coupled receptor signaling pathway
0.65	GO:0002299	alpha-beta intraepithelial T cell differentiation
0.65	GO:0002305	CD8-positive, gamma-delta intraepithelial T cell differentiation
0.63	GO:0043374	CD8-positive, alpha-beta T cell differentiation
0.62	GO:0002689	negative regulation of leukocyte chemotaxis
0.61	GO:0032720	negative regulation of tumor necrosis factor production
0.49	GO:0035025	positive regulation of Rho protein signal transduction
0.47	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.36	GO:1903592	positive regulation of lysozyme activity
0.36	GO:0070472	regulation of uterine smooth muscle contraction

0.71	GO:0004930	G-protein coupled receptor activity
0.36	GO:0001653	peptide receptor activity
0.32	GO:0005515	protein binding

0.42	GO:0005887	integral component of plasma membrane
0.41	GO:0030659	cytoplasmic vesicle membrane
0.36	GO:0061827	sperm head
0.36	GO:0097225	sperm midpiece

sp|Q14331|FRG1_HUMAN
Protein FRG1
Search

FRG1

0.96	FSHD region gene 1

0.50	GO:0007517	muscle organ development
0.45	GO:0008380	RNA splicing
0.45	GO:0006364	rRNA processing
0.44	GO:0006397	mRNA processing
0.36	GO:0043043	peptide biosynthetic process
0.35	GO:0044267	cellular protein metabolic process
0.35	GO:0009059	macromolecule biosynthetic process

0.71	GO:0051015	actin filament binding
0.43	GO:0003723	RNA binding
0.37	GO:0003735	structural constituent of ribosome

0.80	GO:0055120	striated muscle dense body
0.80	GO:0071013	catalytic step 2 spliceosome
0.67	GO:0005730	nucleolus
0.51	GO:0015030	Cajal body
0.51	GO:0030018	Z disc
0.37	GO:0005840	ribosome

sp|Q14332|FZD2_HUMAN
Frizzled-2
Search

FZD2

0.89	Frizzled class receptor 2

0.77	GO:0016055	Wnt signaling pathway
0.69	GO:0007275	multicellular organism development
0.61	GO:0045995	regulation of embryonic development
0.60	GO:0060429	epithelium development
0.59	GO:0060022	hard palate development
0.58	GO:1905276	regulation of epithelial tube formation
0.57	GO:0010562	positive regulation of phosphorus metabolic process
0.56	GO:0090175	regulation of establishment of planar polarity
0.56	GO:0009653	anatomical structure morphogenesis
0.56	GO:0035412	regulation of catenin import into nucleus

0.85	GO:0042813	Wnt-activated receptor activity
0.63	GO:0030165	PDZ domain binding
0.61	GO:0017147	Wnt-protein binding
0.55	GO:0005109	frizzled binding
0.49	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.48	GO:0004930	G-protein coupled receptor activity
0.35	GO:0046982	protein heterodimerization activity
0.35	GO:0042802	identical protein binding
0.35	GO:0045545	syndecan binding
0.33	GO:0004672	protein kinase activity

0.50	GO:0055038	recycling endosome membrane
0.45	GO:0005886	plasma membrane
0.43	GO:0009986	cell surface
0.38	GO:0005925	focal adhesion
0.35	GO:0030669	clathrin-coated endocytic vesicle membrane
0.35	GO:1990909	Wnt signalosome
0.34	GO:0043005	neuron projection
0.30	GO:0016021	integral component of membrane

sp|Q14344|GNA13_HUMAN
Guanine nucleotide-binding protein subunit alpha-13
Search

GNA13

0.93	Heterotrimeric guanine nucleotide binding protein subunit alpha-13

0.74	GO:0007264	small GTPase mediated signal transduction
0.69	GO:0007186	G-protein coupled receptor signaling pathway
0.48	GO:0002009	morphogenesis of an epithelium
0.48	GO:0072359	circulatory system development
0.47	GO:0009790	embryo development
0.46	GO:0019933	cAMP-mediated signaling
0.46	GO:0031584	activation of phospholipase D activity
0.46	GO:0043149	stress fiber assembly
0.46	GO:0030154	cell differentiation
0.45	GO:0048646	anatomical structure formation involved in morphogenesis

0.79	GO:0031683	G-protein beta/gamma-subunit complex binding
0.78	GO:0001664	G-protein coupled receptor binding
0.66	GO:0003924	GTPase activity
0.64	GO:0032550	purine ribonucleoside binding
0.64	GO:0019001	guanyl nucleotide binding
0.63	GO:0004871	signal transducer activity
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0045296	cadherin binding
0.35	GO:0005089	Rho guanyl-nucleotide exchange factor activity

0.44	GO:0031526	brush border membrane
0.44	GO:0005622	intracellular
0.42	GO:1905360	GTPase complex
0.41	GO:0019897	extrinsic component of plasma membrane
0.41	GO:0009898	cytoplasmic side of plasma membrane
0.38	GO:0098797	plasma membrane protein complex
0.38	GO:0005925	focal adhesion
0.38	GO:0031982	vesicle
0.38	GO:0043230	extracellular organelle
0.37	GO:0005615	extracellular space

sp|Q14353|GAMT_HUMAN
Guanidinoacetate N-methyltransferase
Search

GAMT

0.97	Guanidinoacetate N-methyltransferase A

0.77	GO:0006601	creatine biosynthetic process
0.61	GO:0032259	methylation
0.53	GO:0040014	regulation of multicellular organism growth
0.51	GO:0007283	spermatogenesis
0.50	GO:0009887	animal organ morphogenesis
0.45	GO:0046498	S-adenosylhomocysteine metabolic process
0.45	GO:0046500	S-adenosylmethionine metabolic process
0.36	GO:1990402	embryonic liver development
0.35	GO:0006936	muscle contraction

0.85	GO:0030731	guanidinoacetate N-methyltransferase activity
0.35	GO:0042803	protein homodimerization activity

0.40	GO:0005634	nucleus
0.37	GO:0070062	extracellular exosome
0.36	GO:0005737	cytoplasm
0.35	GO:0005902	microvillus
0.30	GO:0016020	membrane

0.85	EC:2.1.1.2	GO:0030731
0.85	KEGG:R01883	GO:0030731

sp|Q14376|GALE_HUMAN
UDP-glucose 4-epimerase
Search

GALE

0.40	UDP-galactose-4-epimerase

0.76	GO:0006012	galactose metabolic process
0.51	GO:0019320	hexose catabolic process
0.36	GO:0061622	glycolytic process through glucose-1-phosphate

0.78	GO:0003978	UDP-glucose 4-epimerase activity
0.50	GO:0042803	protein homodimerization activity
0.42	GO:0003974	UDP-N-acetylglucosamine 4-epimerase activity
0.38	GO:0050662	coenzyme binding
0.38	GO:0004419	hydroxymethylglutaryl-CoA lyase activity

0.36	GO:0070062	extracellular exosome
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.78	EC:5.1.3.2	GO:0003978
0.38	KEGG:R01360	GO:0004419

sp|Q14390|GGTL2_HUMAN
Gamma-glutamyltransferase light chain 2
Search

0.53	Gamma-glutamyltransferase light chain 2

0.79	GO:0006751	glutathione catabolic process
0.61	GO:0006508	proteolysis
0.48	GO:0050727	regulation of inflammatory response
0.48	GO:0006750	glutathione biosynthetic process
0.48	GO:0007283	spermatogenesis
0.46	GO:0019344	cysteine biosynthetic process
0.46	GO:1901748	leukotriene D4 metabolic process
0.44	GO:0002682	regulation of immune system process
0.44	GO:0019370	leukotriene biosynthetic process
0.38	GO:0051604	protein maturation

0.80	GO:0036374	glutathione hydrolase activity
0.40	GO:0103068	leukotriene C4 gamma-glutamyl transferase activity
0.40	GO:0102953	hypoglycin A gamma-glutamyl transpeptidase activity
0.40	GO:0002951	leukotriene-C(4) hydrolase
0.40	GO:0000048	peptidyltransferase activity
0.33	GO:0005515	protein binding

0.46	GO:0031982	vesicle
0.41	GO:0043230	extracellular organelle
0.39	GO:0005615	extracellular space
0.34	GO:0005886	plasma membrane
0.34	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0005783	endoplasmic reticulum
0.30	GO:0016021	integral component of membrane

0.80	EC:3.4.19.13	GO:0036374
0.80	KEGG:R00494	GO:0036374

sp|Q14392|LRC32_HUMAN
Leucine-rich repeat-containing protein 32
Search

LRRC32

0.97	Leucine-rich repeat-containing protein 32

0.70	GO:0046007	negative regulation of activated T cell proliferation
0.67	GO:0050710	negative regulation of cytokine secretion
0.57	GO:0010628	positive regulation of gene expression
0.39	GO:0006182	cGMP biosynthetic process
0.38	GO:0006468	protein phosphorylation
0.36	GO:0035556	intracellular signal transduction
0.35	GO:0030168	platelet activation
0.34	GO:0010376	stomatal complex formation
0.33	GO:1905034	regulation of antifungal innate immune response
0.33	GO:0010375	stomatal complex patterning

0.39	GO:0004383	guanylate cyclase activity
0.38	GO:0004672	protein kinase activity
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005515	protein binding
0.33	GO:0042277	peptide binding
0.32	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.32	GO:0004930	G-protein coupled receptor activity

0.56	GO:0005654	nucleoplasm
0.46	GO:0005887	integral component of plasma membrane

0.39

EC:4.6.1.2

GO:0004383

sp|Q14393|GAS6_HUMAN
Growth arrest-specific protein 6
Search

GAS6

0.97	Growth arrest-specific protein 6

0.67	GO:1900141	regulation of oligodendrocyte apoptotic process
0.66	GO:0097241	hematopoietic stem cell migration to bone marrow
0.66	GO:0071307	cellular response to vitamin K
0.66	GO:0033159	negative regulation of protein import into nucleus, translocation
0.65	GO:2000669	negative regulation of dendritic cell apoptotic process
0.65	GO:0035754	B cell chemotaxis
0.65	GO:0010934	macrophage cytokine production
0.65	GO:1900165	negative regulation of interleukin-6 secretion
0.64	GO:0032825	positive regulation of natural killer cell differentiation
0.64	GO:2000270	negative regulation of fibroblast apoptotic process

0.69	GO:0005509	calcium ion binding
0.63	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.62	GO:0030296	protein tyrosine kinase activator activity
0.62	GO:0001786	phosphatidylserine binding
0.61	GO:0030971	receptor tyrosine kinase binding
0.59	GO:0005245	voltage-gated calcium channel activity
0.58	GO:0060090	molecular adaptor activity
0.56	GO:0048018	receptor ligand activity

0.63	GO:0005576	extracellular region
0.41	GO:0005737	cytoplasm
0.39	GO:0031983	vesicle lumen
0.37	GO:0097708	intracellular vesicle
0.36	GO:0012505	endomembrane system
0.36	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part
0.34	GO:0043231	intracellular membrane-bounded organelle

sp|Q14397|GCKR_HUMAN
Glucokinase regulatory protein
Search

GCKR

0.97	Glucokinase regulator

0.72	GO:0033132	negative regulation of glucokinase activity
0.71	GO:0033133	positive regulation of glucokinase activity
0.68	GO:0000060	protein import into nucleus, translocation
0.63	GO:0001678	cellular glucose homeostasis
0.57	GO:1901135	carbohydrate derivative metabolic process
0.48	GO:0016310	phosphorylation
0.44	GO:0009750	response to fructose
0.42	GO:0070328	triglyceride homeostasis
0.41	GO:0046415	urate metabolic process
0.39	GO:0006110	regulation of glycolytic process

0.53	GO:0097367	carbohydrate derivative binding
0.50	GO:0016301	kinase activity
0.40	GO:0019904	protein domain specific binding
0.39	GO:0004857	enzyme inhibitor activity
0.39	GO:0019899	enzyme binding
0.38	GO:0030246	carbohydrate binding
0.35	GO:0043168	anion binding

0.51	GO:0005634	nucleus
0.40	GO:0031974	membrane-enclosed lumen
0.40	GO:0005829	cytosol
0.38	GO:0044446	intracellular organelle part
0.36	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

sp|Q14406|CSHL_HUMAN
Chorionic somatomammotropin hormone-like 1
Search

0.85	Chorionic somatomammotropin hormone B

0.76	GO:0010469	regulation of receptor activity
0.44	GO:0071375	cellular response to peptide hormone stimulus
0.41	GO:0032094	response to food
0.41	GO:0060416	response to growth hormone
0.41	GO:0040018	positive regulation of multicellular organism growth
0.41	GO:0007259	JAK-STAT cascade
0.40	GO:0032868	response to insulin
0.39	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway

0.79	GO:0005179	hormone activity
0.41	GO:0005131	growth hormone receptor binding
0.38	GO:0046872	metal ion binding

0.66	GO:0005576	extracellular region
0.44	GO:0031982	vesicle
0.42	GO:0012505	endomembrane system
0.38	GO:0043231	intracellular membrane-bounded organelle
0.38	GO:0044444	cytoplasmic part
0.37	GO:0044446	intracellular organelle part
0.37	GO:0043233	organelle lumen
0.35	GO:0005886	plasma membrane

sp|Q14409|GLPK3_HUMAN
Glycerol kinase 3
Search

0.44	Glycerol kinase 3 pseudogene

0.73	GO:0006072	glycerol-3-phosphate metabolic process
0.59	GO:0005975	carbohydrate metabolic process
0.57	GO:0016310	phosphorylation
0.47	GO:0006641	triglyceride metabolic process
0.46	GO:0019751	polyol metabolic process
0.42	GO:0046164	alcohol catabolic process
0.41	GO:1901137	carbohydrate derivative biosynthetic process
0.41	GO:0090407	organophosphate biosynthetic process
0.40	GO:0019217	regulation of fatty acid metabolic process
0.40	GO:0042593	glucose homeostasis

0.78	GO:0004370	glycerol kinase activity
0.37	GO:0032559	adenyl ribonucleotide binding
0.37	GO:0008144	drug binding
0.37	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0042393	histone binding
0.33	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups

0.44	GO:0005739	mitochondrion
0.43	GO:0031968	organelle outer membrane
0.39	GO:0070062	extracellular exosome
0.38	GO:0005829	cytosol
0.36	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.78	EC:2.7.1.30	GO:0004370
0.78	KEGG:R00847	GO:0004370

sp|Q14410|GLPK2_HUMAN
Glycerol kinase 2
Search

0.44	Glycerol kinase 3 pseudogene

0.73	GO:0006072	glycerol-3-phosphate metabolic process
0.59	GO:0005975	carbohydrate metabolic process
0.56	GO:0016310	phosphorylation
0.48	GO:0006641	triglyceride metabolic process
0.46	GO:0019751	polyol metabolic process
0.42	GO:0046164	alcohol catabolic process
0.41	GO:1901137	carbohydrate derivative biosynthetic process
0.41	GO:0090407	organophosphate biosynthetic process
0.40	GO:0019217	regulation of fatty acid metabolic process
0.40	GO:0042593	glucose homeostasis

0.77	GO:0004370	glycerol kinase activity
0.37	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0042393	histone binding
0.33	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups

0.45	GO:0005739	mitochondrion
0.43	GO:0031968	organelle outer membrane
0.38	GO:0070062	extracellular exosome
0.38	GO:0005829	cytosol
0.36	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.77	EC:2.7.1.30	GO:0004370
0.77	KEGG:R00847	GO:0004370

sp|Q14416|GRM2_HUMAN
Metabotropic glutamate receptor 2
Search

GRM2

0.93	Metabotropic glutamate receptor 2

0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.58	GO:0007215	glutamate receptor signaling pathway
0.53	GO:0051966	regulation of synaptic transmission, glutamatergic
0.52	GO:0065009	regulation of molecular function
0.40	GO:0014047	glutamate secretion
0.37	GO:0030818	negative regulation of cAMP biosynthetic process
0.37	GO:0007268	chemical synaptic transmission
0.36	GO:0019233	sensory perception of pain
0.35	GO:0046928	regulation of neurotransmitter secretion
0.35	GO:0051930	regulation of sensory perception of pain

0.71	GO:0004930	G-protein coupled receptor activity
0.63	GO:0005246	calcium channel regulator activity
0.58	GO:0008066	glutamate receptor activity
0.35	GO:0005515	protein binding

0.56	GO:0043005	neuron projection
0.55	GO:0005886	plasma membrane
0.49	GO:0036477	somatodendritic compartment
0.49	GO:0014069	postsynaptic density
0.49	GO:0098793	presynapse
0.48	GO:0120038	plasma membrane bounded cell projection part
0.37	GO:0030054	cell junction
0.35	GO:0097449	astrocyte projection
0.33	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|Q14432|PDE3A_HUMAN
cGMP-inhibited 3',5'-cyclic phosphodiesterase A
Search

PDE3A

0.57	Phosphodiesterase

0.62	GO:0060282	positive regulation of oocyte development
0.62	GO:0019934	cGMP-mediated signaling
0.62	GO:0071321	cellular response to cGMP
0.61	GO:0043117	positive regulation of vascular permeability
0.61	GO:0043116	negative regulation of vascular permeability
0.60	GO:0001556	oocyte maturation
0.59	GO:0006198	cAMP catabolic process
0.58	GO:0040020	regulation of meiotic nuclear division
0.58	GO:0019933	cAMP-mediated signaling
0.57	GO:0071560	cellular response to transforming growth factor beta stimulus

0.78	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.53	GO:0046872	metal ion binding
0.42	GO:0030552	cAMP binding
0.34	GO:0005515	protein binding

0.50	GO:0005829	cytosol
0.37	GO:0032045	guanyl-nucleotide exchange factor complex
0.30	GO:0016020	membrane

0.78

GO:0004114

sp|Q14435|GALT3_HUMAN
Polypeptide N-acetylgalactosaminyltransferase 3
Search

GALNT3

0.64	Polypeptide N-acetylgalactosaminyltransferase

0.73	GO:0043413	macromolecule glycosylation
0.73	GO:0009101	glycoprotein biosynthetic process
0.59	GO:0036211	protein modification process
0.55	GO:0044267	cellular protein metabolic process
0.35	GO:0008543	fibroblast growth factor receptor signaling pathway
0.33	GO:0005975	carbohydrate metabolic process

0.69	GO:0030246	carbohydrate binding
0.65	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity
0.51	GO:0030145	manganese ion binding
0.50	GO:0005509	calcium ion binding
0.33	GO:0005515	protein binding

0.72	GO:0000139	Golgi membrane
0.59	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0070062	extracellular exosome
0.36	GO:0031985	Golgi cisterna
0.30	GO:0016021	integral component of membrane

0.65

EC:2.4.1.41

GO:0004653

sp|Q14439|GP176_HUMAN
G-protein coupled receptor 176
Search

GPR176

0.95	G-protein coupled receptor 176

0.69	GO:0007186	G-protein coupled receptor signaling pathway
0.58	GO:0030818	negative regulation of cAMP biosynthetic process
0.57	GO:0048512	circadian behavior
0.35	GO:0098916	anterograde trans-synaptic signaling

0.70

GO:0004930

G-protein coupled receptor activity

0.42	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q14442|PIGH_HUMAN
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H
Search

PIGH

0.97	Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

0.49

GO:0006506

GPI anchor biosynthetic process

0.83

GO:0017176

phosphatidylinositol N-acetylglucosaminyltransferase activity

0.65	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex
0.30	GO:0031224	intrinsic component of membrane

0.83

EC:2.4.1.198

GO:0017176

sp|Q14444|CAPR1_HUMAN
Caprin-1
Search

CAPRIN1

0.94	Cytoplasmic activation-and proliferation-associated protein 1

0.86	GO:0061003	positive regulation of dendritic spine morphogenesis
0.47	GO:0017148	negative regulation of translation
0.40	GO:1990884	RNA acetylation
0.38	GO:0042274	ribosomal small subunit biogenesis
0.37	GO:0000154	rRNA modification
0.37	GO:0006400	tRNA modification
0.35	GO:0006471	protein ADP-ribosylation

0.41	GO:0003723	RNA binding
0.37	GO:0008080	N-acetyltransferase activity
0.36	GO:0005515	protein binding
0.35	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.79	GO:0010494	cytoplasmic stress granule
0.49	GO:0000932	P-body
0.49	GO:0030425	dendrite
0.44	GO:0005829	cytosol
0.38	GO:0005730	nucleolus
0.37	GO:0005887	integral component of plasma membrane

0.37

EC:2.3.1

GO:0008080

sp|Q14449|GRB14_HUMAN
Growth factor receptor-bound protein 14
Search

GRB14

0.94	Growth factor receptor-bound protein 14

0.75	GO:0009967	positive regulation of signal transduction
0.66	GO:0046627	negative regulation of insulin receptor signaling pathway
0.60	GO:0007165	signal transduction
0.39	GO:0046325	negative regulation of glucose import
0.39	GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway
0.38	GO:0030178	negative regulation of Wnt signaling pathway
0.37	GO:0042326	negative regulation of phosphorylation
0.36	GO:1904145	negative regulation of meiotic cell cycle process involved in oocyte maturation
0.35	GO:0050900	leukocyte migration
0.35	GO:0032869	cellular response to insulin stimulus

0.85	GO:0005070	SH3/SH2 adaptor activity
0.57	GO:0030971	receptor tyrosine kinase binding
0.53	GO:0005158	insulin receptor binding
0.52	GO:0042803	protein homodimerization activity
0.35	GO:0051219	phosphoprotein binding

0.43	GO:0043227	membrane-bounded organelle
0.43	GO:0005886	plasma membrane
0.41	GO:0043229	intracellular organelle
0.39	GO:0005737	cytoplasm
0.38	GO:0098805	whole membrane
0.37	GO:0012505	endomembrane system
0.35	GO:0044422	organelle part
0.35	GO:0043234	protein complex

sp|Q14451|GRB7_HUMAN
Growth factor receptor-bound protein 7
Search

GRB7

0.88	Growth factor receptor-bound protein 7

0.73	GO:0009967	positive regulation of signal transduction
0.61	GO:0007165	signal transduction
0.58	GO:0034063	stress granule assembly
0.57	GO:0046627	negative regulation of insulin receptor signaling pathway
0.54	GO:0030335	positive regulation of cell migration
0.52	GO:0017148	negative regulation of translation
0.43	GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway
0.42	GO:0046325	negative regulation of glucose import
0.42	GO:0030178	negative regulation of Wnt signaling pathway
0.40	GO:0042326	negative regulation of phosphorylation

0.83	GO:0005070	SH3/SH2 adaptor activity
0.57	GO:0005158	insulin receptor binding
0.53	GO:0019901	protein kinase binding
0.52	GO:0035091	phosphatidylinositol binding
0.51	GO:0042802	identical protein binding
0.36	GO:0003723	RNA binding
0.33	GO:0046983	protein dimerization activity

0.55	GO:0005925	focal adhesion
0.54	GO:0010494	cytoplasmic stress granule
0.48	GO:0005829	cytosol
0.37	GO:0042995	cell projection
0.36	GO:0043234	protein complex
0.35	GO:0005886	plasma membrane
0.32	GO:0043231	intracellular membrane-bounded organelle

sp|Q14457|BECN1_HUMAN
Beclin-1
Search

BECN1

0.90	Beclin 1 (Coiled-coil, myosin-like BCL2 interacting protein)

0.79	GO:0032465	regulation of cytokinesis
0.77	GO:0006914	autophagy
0.71	GO:0006897	endocytosis
0.56	GO:0045022	early endosome to late endosome transport
0.54	GO:1902425	positive regulation of attachment of mitotic spindle microtubules to kinetochore
0.54	GO:0050435	amyloid-beta metabolic process
0.54	GO:1902902	negative regulation of autophagosome assembly
0.54	GO:0007033	vacuole organization
0.54	GO:0010613	positive regulation of cardiac muscle hypertrophy
0.53	GO:0098780	response to mitochondrial depolarisation

0.53	GO:0043548	phosphatidylinositol 3-kinase binding
0.50	GO:0031625	ubiquitin protein ligase binding
0.49	GO:0019901	protein kinase binding
0.48	GO:0042803	protein homodimerization activity
0.47	GO:0051020	GTPase binding

0.56	GO:0035032	phosphatidylinositol 3-kinase complex, class III
0.54	GO:0005776	autophagosome
0.52	GO:0045335	phagocytic vesicle
0.50	GO:0005768	endosome
0.50	GO:0005802	trans-Golgi network
0.48	GO:0005783	endoplasmic reticulum
0.47	GO:0000407	phagophore assembly site
0.47	GO:0005829	cytosol
0.44	GO:0005739	mitochondrion
0.42	GO:0043234	protein complex

sp|Q14469|HES1_HUMAN
Transcription factor HES-1
Search

HES1

0.91	BHLH-WRPW transcription factor

0.58	GO:0006351	transcription, DNA-templated
0.58	GO:0061106	negative regulation of stomach neuroendocrine cell differentiation
0.58	GO:2000974	negative regulation of pro-B cell differentiation
0.58	GO:0007262	STAT protein import into nucleus
0.57	GO:2000227	negative regulation of pancreatic A cell differentiation
0.57	GO:0021536	diencephalon development
0.57	GO:0007219	Notch signaling pathway
0.57	GO:0072141	renal interstitial fibroblast development
0.57	GO:0050767	regulation of neurogenesis
0.57	GO:0006355	regulation of transcription, DNA-templated

0.68	GO:0046983	protein dimerization activity
0.58	GO:0071820	N-box binding
0.53	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.53	GO:0042826	histone deacetylase binding
0.50	GO:0051087	chaperone binding
0.49	GO:0042802	identical protein binding
0.40	GO:0008134	transcription factor binding
0.36	GO:0008432	JUN kinase binding
0.36	GO:0070888	E-box binding
0.35	GO:0003682	chromatin binding

0.61	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm
0.36	GO:0070013	intracellular organelle lumen
0.35	GO:0044446	intracellular organelle part
0.34	GO:0005694	chromosome
0.30	GO:0016020	membrane

0.34

EC:3.2.1.23

GO:0004565

sp|Q14493|SLBP_HUMAN
Histone RNA hairpin-binding protein
Search

SLBP

0.86	Stem-loop binding protein (Fragment)

0.75	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage
0.67	GO:0033260	nuclear DNA replication
0.67	GO:0044770	cell cycle phase transition
0.63	GO:0051028	mRNA transport
0.43	GO:0031290	retinal ganglion cell axon guidance
0.42	GO:0003407	neural retina development
0.42	GO:0046530	photoreceptor cell differentiation

0.79	GO:0071207	histone pre-mRNA stem-loop binding
0.76	GO:0003729	mRNA binding

0.75	GO:0071204	histone pre-mRNA 3'end processing complex
0.62	GO:0005730	nucleolus
0.58	GO:0005829	cytosol

sp|Q14494|NF2L1_HUMAN
Nuclear factor erythroid 2-related factor 1
Search

NFE2L1

0.95	Nuclear factor, erythroid 2 like 1

0.70	GO:0045944	positive regulation of transcription by RNA polymerase II
0.70	GO:0034599	cellular response to oxidative stress
0.55	GO:0030218	erythrocyte differentiation
0.51	GO:0006366	transcription by RNA polymerase II
0.30	GO:0045892	negative regulation of transcription, DNA-templated
0.30	GO:0071397	cellular response to cholesterol
0.30	GO:1901566	organonitrogen compound biosynthetic process
0.30	GO:0045454	cell redox homeostasis
0.30	GO:0006778	porphyrin-containing compound metabolic process
0.30	GO:0009653	anatomical structure morphogenesis

0.61	GO:0003700	DNA binding transcription factor activity
0.56	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.55	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.51	GO:0019904	protein domain specific binding
0.50	GO:0032403	protein complex binding
0.30	GO:0046982	protein heterodimerization activity
0.30	GO:0032934	sterol binding
0.30	GO:0000987	proximal promoter sequence-specific DNA binding
0.30	GO:0003712	transcription cofactor activity
0.30	GO:0043178	alcohol binding

0.61	GO:0005634	nucleus
0.49	GO:0005829	cytosol
0.44	GO:0043234	protein complex
0.30	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.30	GO:0098827	endoplasmic reticulum subcompartment
0.30	GO:0016021	integral component of membrane

sp|Q14498|RBM39_HUMAN
RNA-binding protein 39
Search

RBM39

0.85	RNA binding motif protein 39

0.68	GO:0006397	mRNA processing
0.37	GO:0008380	RNA splicing
0.35	GO:0006351	transcription, DNA-templated
0.35	GO:2001141	regulation of RNA biosynthetic process
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression

0.58	GO:0003723	RNA binding
0.35	GO:0003713	transcription coactivator activity
0.35	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.52	GO:0005815	microtubule organizing center
0.48	GO:0031974	membrane-enclosed lumen
0.44	GO:0043234	protein complex

sp|Q14500|KCJ12_HUMAN
ATP-sensitive inward rectifier potassium channel 12
Search

KCNJ12

0.80	Inwardly-rectifying potassium channel

0.78	GO:0034765	regulation of ion transmembrane transport
0.71	GO:0006813	potassium ion transport
0.61	GO:0098655	cation transmembrane transport
0.41	GO:0098660	inorganic ion transmembrane transport
0.40	GO:0051289	protein homotetramerization
0.36	GO:0061337	cardiac conduction
0.35	GO:0006936	muscle contraction

0.84	GO:0005242	inward rectifier potassium channel activity
0.43	GO:0030165	PDZ domain binding

0.43	GO:0044459	plasma membrane part
0.35	GO:0042383	sarcolemma
0.34	GO:0043025	neuronal cell body
0.34	GO:0030425	dendrite
0.33	GO:0098794	postsynapse
0.33	GO:0034705	potassium channel complex
0.33	GO:0030659	cytoplasmic vesicle membrane
0.33	GO:0030054	cell junction

sp|Q14507|EP3A_HUMAN
Epididymal secretory protein E3-alpha
Search

0.97	Epididymal secretory protein E3-alpha

0.68

GO:0007321

sperm displacement

0.45

GO:0005515

protein binding

0.55	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

sp|Q14508|WFDC2_HUMAN
WAP four-disulfide core domain protein 2
Search

WFDC2

0.95	WAP four-disulfide core domain protein 2

0.76	GO:0010466	negative regulation of peptidase activity
0.61	GO:0052548	regulation of endopeptidase activity
0.39	GO:0007283	spermatogenesis
0.36	GO:0006508	proteolysis
0.33	GO:0006413	translational initiation

0.76	GO:0030414	peptidase inhibitor activity
0.61	GO:0061135	endopeptidase regulator activity
0.33	GO:0003743	translation initiation factor activity
0.33	GO:0004252	serine-type endopeptidase activity

0.66	GO:0005576	extracellular region
0.38	GO:0031982	vesicle
0.30	GO:0016020	membrane

0.33

GO:0004252

sp|Q14511|CASL_HUMAN
Enhancer of filamentation 1
Search

NEDD9

0.94	Enhancer of filamentation 1

0.64	GO:0040008	regulation of growth
0.61	GO:0007155	cell adhesion
0.58	GO:0051017	actin filament bundle assembly
0.57	GO:0051301	cell division
0.56	GO:0007049	cell cycle
0.56	GO:0007229	integrin-mediated signaling pathway
0.42	GO:0036032	neural crest cell delamination
0.41	GO:0007045	cell-substrate adherens junction assembly
0.41	GO:0006929	substrate-dependent cell migration
0.39	GO:0030335	positive regulation of cell migration

0.54

GO:0005515

protein binding

0.73	GO:0000922	spindle pole
0.64	GO:0005654	nucleoplasm
0.63	GO:0005829	cytosol
0.63	GO:0005938	cell cortex
0.58	GO:0030027	lamellipodium
0.57	GO:0005925	focal adhesion
0.52	GO:0005886	plasma membrane
0.52	GO:0005794	Golgi apparatus

sp|Q14512|FGFP1_HUMAN
Fibroblast growth factor-binding protein 1
Search

FGFBP1

0.94	Fibroblast growth factor-binding protein 1

0.85	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway
0.74	GO:0008284	positive regulation of cell proliferation
0.45	GO:0007267	cell-cell signaling
0.45	GO:0008543	fibroblast growth factor receptor signaling pathway
0.44	GO:0008285	negative regulation of cell proliferation

0.82	GO:0017134	fibroblast growth factor binding
0.45	GO:0008201	heparin binding

0.71	GO:0009986	cell surface
0.64	GO:0005576	extracellular region
0.42	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q14515|SPRL1_HUMAN
SPARC-like protein 1
Search

SPARCL1

0.91	SPARC like 1

0.60	GO:0007165	signal transduction
0.42	GO:0048856	anatomical structure development
0.37	GO:0001937	negative regulation of endothelial cell proliferation
0.37	GO:0010595	positive regulation of endothelial cell migration
0.37	GO:0016525	negative regulation of angiogenesis
0.36	GO:0034101	erythrocyte homeostasis
0.36	GO:0032501	multicellular organismal process
0.36	GO:0043473	pigmentation
0.35	GO:0071363	cellular response to growth factor stimulus
0.35	GO:0022604	regulation of cell morphogenesis

0.84	GO:0050840	extracellular matrix binding
0.83	GO:0005518	collagen binding
0.70	GO:0005509	calcium ion binding

0.76	GO:0005578	proteinaceous extracellular matrix
0.73	GO:0005615	extracellular space
0.38	GO:0031092	platelet alpha granule membrane
0.37	GO:0016363	nuclear matrix
0.36	GO:0009986	cell surface
0.36	GO:0044420	extracellular matrix component
0.35	GO:1903561	extracellular vesicle
0.35	GO:0045202	synapse
0.30	GO:0005783	endoplasmic reticulum

sp|Q14517|FAT1_HUMAN
Protocadherin Fat 1
Search

FAT1

0.66	FAT atypical cadherin 1

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.48	GO:0007163	establishment or maintenance of cell polarity
0.46	GO:0007015	actin filament organization
0.40	GO:0048793	pronephros development
0.39	GO:0003382	epithelial cell morphogenesis
0.38	GO:0048593	camera-type eye morphogenesis
0.36	GO:0016477	cell migration
0.34	GO:0007186	G-protein coupled receptor signaling pathway
0.30	GO:0007267	cell-cell signaling

0.70	GO:0005509	calcium ion binding
0.36	GO:0005515	protein binding
0.35	GO:0008502	melatonin receptor activity

0.55	GO:0005886	plasma membrane
0.50	GO:0030175	filopodium
0.49	GO:0048471	perinuclear region of cytoplasm
0.49	GO:0030027	lamellipodium
0.48	GO:0005911	cell-cell junction
0.42	GO:0005634	nucleus
0.38	GO:0005925	focal adhesion
0.38	GO:0070062	extracellular exosome
0.38	GO:0045177	apical part of cell
0.30	GO:0016021	integral component of membrane

sp|Q14520|HABP2_HUMAN
Hyaluronan-binding protein 2
Search

HABP2

0.97	LOW QUALITY PROTEIN: hyaluronan-binding protein 2

0.63	GO:0007596	blood coagulation
0.60	GO:0006508	proteolysis
0.37	GO:1904975	response to bleomycin
0.35	GO:0007155	cell adhesion
0.33	GO:0006898	receptor-mediated endocytosis
0.32	GO:1904627	response to phorbol 13-acetate 12-myristate
0.32	GO:0016310	phosphorylation
0.31	GO:0006259	DNA metabolic process

0.69	GO:0004252	serine-type endopeptidase activity
0.65	GO:0005509	calcium ion binding
0.35	GO:0005539	glycosaminoglycan binding
0.34	GO:0005044	scavenger receptor activity
0.32	GO:0004531	deoxyribonuclease II activity
0.32	GO:0030246	carbohydrate binding
0.32	GO:0016301	kinase activity

0.64	GO:0005576	extracellular region
0.35	GO:0001669	acrosomal vesicle
0.30	GO:0016020	membrane

0.69

GO:0004252

sp|Q14524|SCN5A_HUMAN
Sodium channel protein type 5 subunit alpha
Search

SCN5A

0.66	Sodium voltage-gated channel alpha subunit 5

0.77	GO:0034765	regulation of ion transmembrane transport
0.77	GO:0035725	sodium ion transmembrane transport
0.54	GO:0001508	action potential
0.53	GO:0035637	multicellular organismal signaling
0.53	GO:0019233	sensory perception of pain
0.52	GO:0051899	membrane depolarization
0.49	GO:0060371	regulation of atrial cardiac muscle cell membrane depolarization
0.48	GO:0055117	regulation of cardiac muscle contraction
0.47	GO:0002027	regulation of heart rate
0.44	GO:0007267	cell-cell signaling

0.84	GO:0005248	voltage-gated sodium channel activity
0.74	GO:0022832	voltage-gated channel activity
0.72	GO:0022839	ion gated channel activity
0.71	GO:0008381	mechanosensitive ion channel activity
0.47	GO:0044325	ion channel binding
0.41	GO:0050998	nitric-oxide synthase binding
0.40	GO:0030506	ankyrin binding
0.40	GO:0017134	fibroblast growth factor binding
0.40	GO:0097110	scaffold protein binding
0.39	GO:0031625	ubiquitin protein ligase binding

0.83	GO:0001518	voltage-gated sodium channel complex
0.40	GO:0030315	T-tubule
0.40	GO:0014704	intercalated disc
0.40	GO:0016328	lateral plasma membrane
0.39	GO:0005901	caveola
0.39	GO:0030018	Z disc
0.38	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0009986	cell surface
0.37	GO:0005783	endoplasmic reticulum
0.36	GO:0044299	C-fiber

sp|Q14525|KT33B_HUMAN
Keratin, type I cuticular Ha3-II
Search

0.96	Keratin, type I cuticular Ha3-II

0.43	GO:0042633	hair cycle
0.41	GO:0007568	aging
0.40	GO:0070268	cornification
0.40	GO:0045616	regulation of keratinocyte differentiation
0.34	GO:0007010	cytoskeleton organization

0.62	GO:0005198	structural molecule activity
0.35	GO:0005515	protein binding

0.79	GO:0005882	intermediate filament
0.40	GO:0070062	extracellular exosome
0.37	GO:0005829	cytosol

sp|Q14526|HIC1_HUMAN
Hypermethylated in cancer 1 protein
Search

0.95	HIC ZBTB transcriptional repressor 1

0.76	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage
0.70	GO:0000122	negative regulation of transcription by RNA polymerase II
0.57	GO:0030178	negative regulation of Wnt signaling pathway
0.43	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator
0.39	GO:0016055	Wnt signaling pathway
0.38	GO:0007275	multicellular organism development
0.36	GO:0006351	transcription, DNA-templated

0.58	GO:0042826	histone deacetylase binding
0.57	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.51	GO:0003676	nucleic acid binding
0.43	GO:0008022	protein C-terminus binding
0.38	GO:0046872	metal ion binding

0.51	GO:0005654	nucleoplasm
0.50	GO:0005829	cytosol
0.39	GO:0000785	chromatin

sp|Q14527|HLTF_HUMAN
Helicase-like transcription factor
Search

HLTF

0.97	Helicase like transcription factor

0.55	GO:0006366	transcription by RNA polymerase II
0.54	GO:0045944	positive regulation of transcription by RNA polymerase II
0.39	GO:0016567	protein ubiquitination
0.38	GO:0016569	covalent chromatin modification
0.34	GO:0006825	copper ion transport
0.34	GO:0006879	cellular iron ion homeostasis
0.32	GO:0055114	oxidation-reduction process

0.61	GO:0008270	zinc ion binding
0.58	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.58	GO:0004386	helicase activity
0.57	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.57	GO:0031625	ubiquitin protein ligase binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0016887	ATPase activity
0.39	GO:0061630	ubiquitin protein ligase activity

0.52	GO:0005654	nucleoplasm
0.38	GO:0005730	nucleolus
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.47

GO:0016887

sp|Q14532|K1H2_HUMAN
Keratin, type I cuticular Ha2
Search

0.96	Keratin, type I cuticular Ha3-I

0.45	GO:0045616	regulation of keratinocyte differentiation
0.40	GO:0042633	hair cycle
0.40	GO:0070268	cornification
0.39	GO:0007568	aging
0.33	GO:0009653	anatomical structure morphogenesis
0.33	GO:0007010	cytoskeleton organization

0.62	GO:0005198	structural molecule activity
0.34	GO:0005515	protein binding

0.79	GO:0005882	intermediate filament
0.42	GO:0070062	extracellular exosome
0.37	GO:0005829	cytosol

sp|Q14533|KRT81_HUMAN
Keratin, type II cuticular Hb1
Search

0.92	keratin, type II microfibrillar, component 7C

0.41	GO:0042633	hair cycle
0.40	GO:0007568	aging
0.39	GO:0070268	cornification
0.36	GO:0045103	intermediate filament-based process
0.35	GO:0007010	cytoskeleton organization
0.33	GO:0006811	ion transport

0.62	GO:0005198	structural molecule activity
0.35	GO:0005515	protein binding

0.83	GO:0045095	keratin filament
0.42	GO:0005615	extracellular space
0.39	GO:1903561	extracellular vesicle
0.36	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q14534|ERG1_HUMAN
Squalene monooxygenase
Search

SQLE

0.84	Squalene monooxygenase

0.53	GO:0055114	oxidation-reduction process
0.50	GO:0008203	cholesterol metabolic process
0.48	GO:0016126	sterol biosynthetic process
0.39	GO:0010033	response to organic substance
0.36	GO:0045540	regulation of cholesterol biosynthetic process
0.36	GO:1902653	secondary alcohol biosynthetic process
0.34	GO:0006725	cellular aromatic compound metabolic process
0.34	GO:0008204	ergosterol metabolic process
0.34	GO:0044108	cellular alcohol biosynthetic process
0.34	GO:0016129	phytosteroid biosynthetic process

0.85	GO:0004506	squalene monooxygenase activity
0.66	GO:0050660	flavin adenine dinucleotide binding
0.32	GO:0008144	drug binding

0.45	GO:0005783	endoplasmic reticulum
0.37	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0031984	organelle subcompartment
0.35	GO:0031090	organelle membrane
0.33	GO:0005811	lipid droplet
0.30	GO:0016021	integral component of membrane

0.85	EC:1.14.13.132	GO:0004506
0.85	KEGG:R02874	GO:0004506

sp|Q14541|HNF4G_HUMAN
Hepatocyte nuclear factor 4-gamma
Search

HNF4G

0.97	Hepatocyte nuclear factor 4 gamma

0.79	GO:0043401	steroid hormone mediated signaling pathway
0.73	GO:0030522	intracellular receptor signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.50	GO:0051254	positive regulation of RNA metabolic process
0.50	GO:0010557	positive regulation of macromolecule biosynthetic process
0.50	GO:0031328	positive regulation of cellular biosynthetic process
0.47	GO:2000189	positive regulation of cholesterol homeostasis

0.80	GO:0003707	steroid hormone receptor activity
0.76	GO:0004879	nuclear receptor activity
0.64	GO:0043565	sequence-specific DNA binding
0.63	GO:0008270	zinc ion binding
0.53	GO:0001012	RNA polymerase II regulatory region DNA binding
0.50	GO:0003690	double-stranded DNA binding
0.45	GO:0001102	RNA polymerase II activating transcription factor binding
0.45	GO:0005504	fatty acid binding
0.45	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.44	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.40	GO:0070013	intracellular organelle lumen
0.37	GO:0044446	intracellular organelle part
0.35	GO:0005737	cytoplasm
0.34	GO:0005667	transcription factor complex

0.34

EC:3.1.2.2

GO:0016290

sp|Q14542|S29A2_HUMAN
Equilibrative nucleoside transporter 2
Search

SLC29A2

0.90	Equilibrative nitrobenzylmercaptopurine riboside-insensitive nucleoside transporter

0.79	GO:1901642	nucleoside transmembrane transport
0.39	GO:0015862	uridine transport
0.38	GO:0007595	lactation
0.37	GO:0035364	thymine transport
0.36	GO:0035344	hypoxanthine transport
0.36	GO:0015853	adenine transport
0.36	GO:0015854	guanine transport
0.36	GO:1901701	cellular response to oxygen-containing compound
0.36	GO:0071310	cellular response to organic substance
0.36	GO:0030431	sleep

0.78	GO:0005337	nucleoside transmembrane transporter activity
0.33	GO:0005515	protein binding

0.67	GO:0005887	integral component of plasma membrane
0.58	GO:0016323	basolateral plasma membrane
0.40	GO:0016324	apical plasma membrane
0.37	GO:0031965	nuclear membrane
0.35	GO:0098794	postsynapse
0.35	GO:0005730	nucleolus
0.33	GO:0005765	lysosomal membrane

sp|Q14549|GBX1_HUMAN
Homeobox protein GBX-1
Search

0.94	LOW QUALITY PROTEIN: homeobox protein GBX-1

0.61	GO:0021953	central nervous system neuron differentiation
0.60	GO:0007411	axon guidance
0.60	GO:0019230	proprioception
0.58	GO:0007628	adult walking behavior
0.57	GO:0021517	ventral spinal cord development
0.57	GO:0021515	cell differentiation in spinal cord
0.56	GO:0048663	neuron fate commitment
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression

0.63	GO:0043565	sequence-specific DNA binding
0.50	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.49	GO:0001047	core promoter binding
0.48	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.47	GO:0001012	RNA polymerase II regulatory region DNA binding
0.45	GO:0003690	double-stranded DNA binding

0.60

GO:0005634

nucleus

sp|Q14554|PDIA5_HUMAN
Protein disulfide-isomerase A5
Search

PDIA5

0.87	Protein disulfide isomerase family A member 5

0.68	GO:0045454	cell redox homeostasis
0.46	GO:0034976	response to endoplasmic reticulum stress
0.42	GO:0006457	protein folding
0.40	GO:0055114	oxidation-reduction process
0.40	GO:0030097	hemopoiesis
0.33	GO:0034620	cellular response to unfolded protein
0.32	GO:0007165	signal transduction

0.56	GO:0016853	isomerase activity
0.54	GO:0015037	peptide disulfide oxidoreductase activity
0.39	GO:0140096	catalytic activity, acting on a protein
0.32	GO:0005515	protein binding

0.43	GO:0005783	endoplasmic reticulum
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.30	GO:0016021	integral component of membrane

0.56

GO:0016853

sp|Q14558|KPRA_HUMAN
Phosphoribosyl pyrophosphate synthase-associated protein 1
Search

PRPSAP1

0.97	Phosphoribosyl pyrophosphate synthetase-associated protein 1

0.64	GO:0009165	nucleotide biosynthetic process
0.62	GO:0009116	nucleoside metabolic process
0.35	GO:0043086	negative regulation of catalytic activity
0.34	GO:0043549	regulation of kinase activity
0.34	GO:0042326	negative regulation of phosphorylation
0.33	GO:0016310	phosphorylation

0.78	GO:0004749	ribose phosphate diphosphokinase activity
0.64	GO:0000287	magnesium ion binding
0.49	GO:0042802	identical protein binding
0.35	GO:0030234	enzyme regulator activity
0.34	GO:0019900	kinase binding
0.33	GO:0016301	kinase activity

0.35	GO:0002189	ribose phosphate diphosphokinase complex
0.33	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.78	EC:2.7.6.1	GO:0004749
0.78	KEGG:R01049	GO:0004749

sp|Q14562|DHX8_HUMAN
ATP-dependent RNA helicase DHX8
Search

DHX8

0.95	DEAH-box helicase 8

0.53	GO:0008380	RNA splicing
0.51	GO:0006397	mRNA processing
0.51	GO:0060215	primitive hemopoiesis
0.43	GO:0051301	cell division

0.67	GO:0004386	helicase activity
0.59	GO:0042802	identical protein binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0003676	nucleic acid binding
0.49	GO:0008186	RNA-dependent ATPase activity
0.43	GO:0140098	catalytic activity, acting on RNA

0.67	GO:0071007	U2-type catalytic step 2 spliceosome
0.61	GO:0016604	nuclear body
0.38	GO:0005737	cytoplasm

sp|Q14563|SEM3A_HUMAN
Semaphorin-3A
Search

SEMA3A

0.97	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa

0.84	GO:1903045	neural crest cell migration involved in sympathetic nervous system development
0.84	GO:0050919	negative chemotaxis
0.84	GO:2001224	positive regulation of neuron migration
0.83	GO:1903375	facioacoustic ganglion development
0.83	GO:0021828	gonadotrophin-releasing hormone neuronal migration to the hypothalamus
0.83	GO:0036486	ventral trunk neural crest cell migration
0.83	GO:0097490	sympathetic neuron projection extension
0.83	GO:0097491	sympathetic neuron projection guidance
0.82	GO:0140059	dendrite arborization
0.82	GO:1902287	semaphorin-plexin signaling pathway involved in axon guidance

0.85	GO:0038191	neuropilin binding
0.81	GO:0045499	chemorepellent activity
0.81	GO:0030215	semaphorin receptor binding

0.71	GO:0005615	extracellular space
0.63	GO:0030424	axon
0.45	GO:0030425	dendrite
0.44	GO:0044297	cell body
0.30	GO:0016020	membrane

sp|Q14565|DMC1_HUMAN
Meiotic recombination protein DMC1/LIM15 homolog
Search

DMC1

0.97	DNA meiotic recombinase 1 transcript variant

0.79	GO:0007131	reciprocal meiotic recombination
0.65	GO:0006281	DNA repair
0.57	GO:0001556	oocyte maturation
0.56	GO:0007141	male meiosis I
0.55	GO:0070192	chromosome organization involved in meiotic cell cycle
0.55	GO:0001541	ovarian follicle development
0.54	GO:0045143	homologous chromosome segregation
0.54	GO:0007286	spermatid development
0.49	GO:0042148	strand invasion
0.48	GO:0090735	DNA repair complex assembly

0.69	GO:0008094	DNA-dependent ATPase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.55	GO:0003677	DNA binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0000150	recombinase activity
0.44	GO:0004520	endodeoxyribonuclease activity
0.34	GO:0003908	methylated-DNA-[protein]-cysteine S-methyltransferase activity
0.34	GO:0004386	helicase activity
0.33	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.52	GO:0000781	chromosome, telomeric region
0.52	GO:0000793	condensed chromosome
0.48	GO:0031974	membrane-enclosed lumen
0.32	GO:0005737	cytoplasm

0.34

EC:2.1.1.63

GO:0003908

sp|Q14566|MCM6_HUMAN
DNA replication licensing factor MCM6
Search

MCM6

0.44	Zygotic DNA replication licensing factor mcm6-B

0.75	GO:0006270	DNA replication initiation
0.67	GO:0032392	DNA geometric change
0.59	GO:0007049	cell cycle
0.57	GO:0030174	regulation of DNA-dependent DNA replication initiation

0.67	GO:0003678	DNA helicase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.55	GO:0003677	DNA binding
0.54	GO:0003682	chromatin binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0042802	identical protein binding
0.49	GO:0070035	purine NTP-dependent helicase activity
0.48	GO:0008094	DNA-dependent ATPase activity
0.44	GO:0046872	metal ion binding

0.76	GO:0042555	MCM complex
0.59	GO:0005634	nucleus
0.50	GO:0044427	chromosomal part
0.47	GO:0031974	membrane-enclosed lumen

sp|Q14568|HS902_HUMAN
Heat shock protein HSP 90-alpha A2
Search

0.57	Heat shock protein HSP 90-alpha

0.69	GO:0006457	protein folding
0.64	GO:0009409	response to cold
0.61	GO:0009408	response to heat
0.60	GO:0046677	response to antibiotic
0.52	GO:1905323	telomerase holoenzyme complex assembly
0.50	GO:0045429	positive regulation of nitric oxide biosynthetic process
0.50	GO:0051973	positive regulation of telomerase activity
0.50	GO:0007004	telomere maintenance via telomerase
0.49	GO:0045040	protein import into mitochondrial outer membrane
0.48	GO:0051131	chaperone-mediated protein complex assembly

0.71	GO:0051082	unfolded protein binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0030235	nitric-oxide synthase regulator activity
0.53	GO:0030911	TPR domain binding
0.51	GO:0070182	DNA polymerase binding
0.50	GO:0097718	disordered domain specific binding
0.50	GO:0097110	scaffold protein binding

0.52	GO:0005634	nucleus
0.48	GO:0032587	ruffle membrane
0.47	GO:0043209	myelin sheath
0.44	GO:0042470	melanosome
0.44	GO:0005829	cytosol
0.40	GO:0043234	protein complex
0.39	GO:0097226	sperm mitochondrial sheath
0.38	GO:0097524	sperm plasma membrane
0.38	GO:0043025	neuronal cell body
0.38	GO:0030018	Z disc

0.42

GO:0016887

sp|Q14571|ITPR2_HUMAN
Inositol 1,4,5-trisphosphate receptor type 2
Search

ITPR2

0.90	Inositol trisphosphate receptor type 2

0.84	GO:0048016	inositol phosphate-mediated signaling
0.76	GO:0070588	calcium ion transmembrane transport
0.58	GO:0051283	negative regulation of sequestering of calcium ion
0.58	GO:0060402	calcium ion transport into cytosol
0.57	GO:0071361	cellular response to ethanol
0.56	GO:0071320	cellular response to cAMP
0.56	GO:0001666	response to hypoxia
0.41	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
0.40	GO:0050882	voluntary musculoskeletal movement
0.40	GO:0042045	epithelial fluid transport

0.85	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
0.84	GO:0070679	inositol 1,4,5 trisphosphate binding
0.57	GO:0097110	scaffold protein binding
0.53	GO:0035091	phosphatidylinositol binding
0.44	GO:0005509	calcium ion binding
0.40	GO:0019855	calcium channel inhibitor activity
0.34	GO:0051287	NAD binding
0.34	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
0.31	GO:0016787	hydrolase activity

0.69	GO:0005783	endoplasmic reticulum
0.57	GO:0016528	sarcoplasm
0.53	GO:0043235	receptor complex
0.52	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.51	GO:0005938	cell cortex
0.51	GO:0098588	bounding membrane of organelle
0.50	GO:0031984	organelle subcompartment
0.46	GO:0005634	nucleus
0.43	GO:0005886	plasma membrane
0.42	GO:0031094	platelet dense tubular network

0.34

GO:0016616

sp|Q14573|ITPR3_HUMAN
Inositol 1,4,5-trisphosphate receptor type 3
Search

ITPR3

0.87	LOW QUALITY PROTEIN: inositol 1,4,5-trisphosphate receptor type 3

0.84	GO:0048016	inositol phosphate-mediated signaling
0.76	GO:0070588	calcium ion transmembrane transport
0.60	GO:0050917	sensory perception of umami taste
0.59	GO:0051283	negative regulation of sequestering of calcium ion
0.58	GO:0060402	calcium ion transport into cytosol
0.58	GO:0050916	sensory perception of sweet taste
0.57	GO:0050913	sensory perception of bitter taste
0.57	GO:0060291	long-term synaptic potentiation
0.56	GO:0051592	response to calcium ion
0.56	GO:0007613	memory

0.85	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
0.84	GO:0070679	inositol 1,4,5 trisphosphate binding
0.53	GO:0035091	phosphatidylinositol binding
0.44	GO:0005509	calcium ion binding
0.39	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding
0.38	GO:0000822	inositol hexakisphosphate binding
0.38	GO:0097110	scaffold protein binding
0.32	GO:0005089	Rho guanyl-nucleotide exchange factor activity

0.69	GO:0005783	endoplasmic reticulum
0.54	GO:0043235	receptor complex
0.51	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.51	GO:0005730	nucleolus
0.49	GO:0031984	organelle subcompartment
0.49	GO:0005654	nucleoplasm
0.48	GO:0005887	integral component of plasma membrane
0.39	GO:0098588	bounding membrane of organelle
0.38	GO:0016528	sarcoplasm
0.38	GO:0005903	brush border

sp|Q14574|DSC3_HUMAN
Desmocollin-3
Search

DSC3

0.97	Desmocollin-3

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.52	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication
0.52	GO:0098911	regulation of ventricular cardiac muscle cell action potential
0.51	GO:0086091	regulation of heart rate by cardiac conduction
0.47	GO:0009267	cellular response to starvation
0.39	GO:0050821	protein stabilization
0.39	GO:0070268	cornification
0.38	GO:0001701	in utero embryonic development
0.34	GO:0043312	neutrophil degranulation
0.34	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules

0.70	GO:0005509	calcium ion binding
0.41	GO:0045295	gamma-catenin binding
0.36	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication

0.56	GO:0005886	plasma membrane
0.55	GO:0030054	cell junction
0.46	GO:0031982	vesicle
0.39	GO:0043230	extracellular organelle
0.39	GO:0044444	cytoplasmic part
0.38	GO:0043229	intracellular organelle
0.38	GO:0005615	extracellular space
0.33	GO:0098805	whole membrane
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0012505	endomembrane system

sp|Q14576|ELAV3_HUMAN
ELAV-like protein 3
Search

ELAVL3

0.77	ELAV-like protein 3

0.71	GO:0007399	nervous system development
0.68	GO:0030154	cell differentiation

0.74

GO:0017091

AU-rich element binding

0.48	GO:1990904	ribonucleoprotein complex
0.39	GO:0044424	intracellular part

sp|Q14582|MAD4_HUMAN
Max dimerization protein 4
Search

MXD4

0.97	MAX dimerization protein 4

0.40	GO:0000122	negative regulation of transcription by RNA polymerase II
0.35	GO:0006351	transcription, DNA-templated
0.35	GO:0008285	negative regulation of cell proliferation

0.66	GO:0046983	protein dimerization activity
0.40	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.39	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.35	GO:0003714	transcription corepressor activity
0.34	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.33	GO:0000987	proximal promoter sequence-specific DNA binding

0.40	GO:0005634	nucleus
0.38	GO:0005667	transcription factor complex
0.36	GO:0044446	intracellular organelle part
0.34	GO:0005829	cytosol
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0043232	intracellular non-membrane-bounded organelle
0.32	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

sp|Q14584|ZN266_HUMAN
Zinc finger protein 266
Search

0.43	Zinc finger domain-containing protein (Fragment)

0.54	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.53	GO:0010468	regulation of gene expression
0.37	GO:0006351	transcription, DNA-templated
0.36	GO:0007283	spermatogenesis
0.36	GO:0051321	meiotic cell cycle
0.35	GO:1902679	negative regulation of RNA biosynthetic process

0.51	GO:0003676	nucleic acid binding
0.51	GO:0046872	metal ion binding
0.41	GO:0003700	DNA binding transcription factor activity
0.39	GO:0003682	chromatin binding
0.34	GO:0005515	protein binding

0.43	GO:0005622	intracellular
0.37	GO:0043227	membrane-bounded organelle

sp|Q14585|ZN345_HUMAN
Zinc finger protein 345
Search

0.68	Zinc finger protein 331 (Predicted)

0.53	GO:1903506	regulation of nucleic acid-templated transcription
0.53	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.53	GO:0010468	regulation of gene expression
0.40	GO:0060443	mammary gland morphogenesis
0.40	GO:0048286	lung alveolus development
0.40	GO:0010453	regulation of cell fate commitment
0.39	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.38	GO:0007186	G-protein coupled receptor signaling pathway
0.36	GO:0006351	transcription, DNA-templated
0.30	GO:0009890	negative regulation of biosynthetic process

0.51	GO:0003676	nucleic acid binding
0.51	GO:0046872	metal ion binding
0.44	GO:0003700	DNA binding transcription factor activity
0.39	GO:0004984	olfactory receptor activity
0.38	GO:0004930	G-protein coupled receptor activity

0.43	GO:0005622	intracellular
0.40	GO:0043227	membrane-bounded organelle
0.35	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q14586|ZN267_HUMAN
Zinc finger protein 267
Search

0.68	Zinc finger protein 85

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.37	GO:0035108	limb morphogenesis
0.35	GO:0006351	transcription, DNA-templated

0.51	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.35	GO:0003700	DNA binding transcription factor activity

0.44	GO:0005622	intracellular
0.35	GO:0043227	membrane-bounded organelle
0.34	GO:0043230	extracellular organelle
0.33	GO:0005615	extracellular space
0.32	GO:0043233	organelle lumen

sp|Q14587|ZN268_HUMAN
Zinc finger protein 268
Search

0.67	Zinc finger protein 268

0.54	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.46	GO:0071157	negative regulation of cell cycle arrest
0.44	GO:0030335	positive regulation of cell migration
0.44	GO:0008285	negative regulation of cell proliferation
0.44	GO:0008284	positive regulation of cell proliferation
0.44	GO:0043065	positive regulation of apoptotic process
0.44	GO:0045597	positive regulation of cell differentiation
0.43	GO:0043066	negative regulation of apoptotic process

0.51	GO:0003676	nucleic acid binding
0.50	GO:0046872	metal ion binding
0.44	GO:0003700	DNA binding transcription factor activity
0.38	GO:0042802	identical protein binding
0.35	GO:0003735	structural constituent of ribosome

0.43	GO:0005622	intracellular
0.40	GO:0043227	membrane-bounded organelle
0.39	GO:0043228	non-membrane-bounded organelle
0.35	GO:1990904	ribonucleoprotein complex
0.32	GO:0031974	membrane-enclosed lumen
0.32	GO:0044422	organelle part

sp|Q14588|ZN234_HUMAN
Zinc finger protein 234
Search

0.75	Zinc finger protein 227

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.41	GO:1902679	negative regulation of RNA biosynthetic process
0.39	GO:0006351	transcription, DNA-templated

0.52	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.45	GO:0003700	DNA binding transcription factor activity
0.37	GO:0005515	protein binding

0.44	GO:0005622	intracellular
0.43	GO:0017053	transcriptional repressor complex
0.41	GO:0043227	membrane-bounded organelle
0.40	GO:0012505	endomembrane system
0.38	GO:0031975	envelope
0.37	GO:0044422	organelle part
0.30	GO:0016020	membrane

sp|Q14590|ZN235_HUMAN
Zinc finger protein 235
Search

0.67	Zinc finger protein 235

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.35	GO:0006351	transcription, DNA-templated

0.51	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.45	GO:0003700	DNA binding transcription factor activity

0.44	GO:0005622	intracellular
0.38	GO:0031974	membrane-enclosed lumen
0.37	GO:0043227	membrane-bounded organelle
0.36	GO:0044422	organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|Q14592|ZN460_HUMAN
Zinc finger protein 460
Search

0.83	Zinc finger domain-containing protein (Fragment)

0.54	GO:1903506	regulation of nucleic acid-templated transcription
0.54	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.53	GO:0010468	regulation of gene expression
0.37	GO:0035108	limb morphogenesis
0.35	GO:0006468	protein phosphorylation
0.35	GO:0006351	transcription, DNA-templated

0.51	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.35	GO:0004672	protein kinase activity
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003700	DNA binding transcription factor activity
0.30	GO:0005515	protein binding

0.43	GO:0005622	intracellular
0.35	GO:0043227	membrane-bounded organelle

sp|Q14593|ZN273_HUMAN
Zinc finger protein 273
Search

0.86	Zinc finger protein 675

0.83	GO:2000660	negative regulation of interleukin-1-mediated signaling pathway
0.80	GO:0043508	negative regulation of JUN kinase activity
0.79	GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway
0.79	GO:0045671	negative regulation of osteoclast differentiation
0.78	GO:2000678	negative regulation of transcription regulatory region DNA binding
0.76	GO:0007249	I-kappaB kinase/NF-kappaB signaling
0.76	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.71	GO:0019221	cytokine-mediated signaling pathway
0.69	GO:0000122	negative regulation of transcription by RNA polymerase II
0.55	GO:0045453	bone resorption

0.70	GO:0031625	ubiquitin protein ligase binding
0.54	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding

0.70	GO:0048471	perinuclear region of cytoplasm
0.56	GO:0005634	nucleus

sp|Q14596|NBR1_HUMAN
Next to BRCA1 gene 1 protein
Search

NBR1

0.97	NBR1, autophagy cargo receptor

0.77	GO:0016236	macroautophagy
0.72	GO:0045668	negative regulation of osteoblast differentiation
0.71	GO:0030500	regulation of bone mineralization
0.68	GO:0032872	regulation of stress-activated MAPK cascade
0.61	GO:0051259	protein oligomerization

0.77	GO:0043130	ubiquitin binding
0.73	GO:0051019	mitogen-activated protein kinase binding
0.63	GO:0008270	zinc ion binding

0.72	GO:0005776	autophagosome
0.71	GO:0000407	phagophore assembly site
0.67	GO:0005770	late endosome
0.65	GO:0016604	nuclear body
0.58	GO:0005829	cytosol
0.52	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

sp|Q14602|ID2B_HUMAN
Putative DNA-binding protein inhibitor ID-2B
Search

0.79	Putative DNA-binding protein inhibitor ID-2B

0.72	GO:0045892	negative regulation of transcription, DNA-templated
0.61	GO:0061031	endodermal digestive tract morphogenesis
0.59	GO:0045777	positive regulation of blood pressure
0.59	GO:0045578	negative regulation of B cell differentiation
0.59	GO:0048557	embryonic digestive tract morphogenesis
0.59	GO:0003166	bundle of His development
0.59	GO:0090398	cellular senescence
0.59	GO:2000178	negative regulation of neural precursor cell proliferation
0.58	GO:0071158	positive regulation of cell cycle arrest
0.58	GO:0048661	positive regulation of smooth muscle cell proliferation

0.68	GO:0046983	protein dimerization activity
0.57	GO:0044325	ion channel binding
0.46	GO:0003677	DNA binding
0.40	GO:0043425	bHLH transcription factor binding
0.34	GO:0004930	G-protein coupled receptor activity
0.33	GO:0003700	DNA binding transcription factor activity

0.61	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.45	GO:0043234	protein complex
0.34	GO:0000785	chromatin
0.30	GO:0031224	intrinsic component of membrane

sp|Q14623|IHH_HUMAN
Indian hedgehog protein
Search

IHH

0.85	Indian hedgehog

0.74	GO:0016539	intein-mediated protein splicing
0.74	GO:0007267	cell-cell signaling
0.69	GO:0007275	multicellular organism development
0.64	GO:0033084	regulation of immature T cell proliferation in thymus
0.64	GO:0033089	positive regulation of T cell differentiation in thymus
0.63	GO:0046639	negative regulation of alpha-beta T cell differentiation
0.62	GO:0002053	positive regulation of mesenchymal cell proliferation
0.62	GO:0045880	positive regulation of smoothened signaling pathway
0.62	GO:0046638	positive regulation of alpha-beta T cell differentiation
0.62	GO:0001649	osteoblast differentiation

0.65	GO:0005113	patched binding
0.60	GO:0008233	peptidase activity
0.53	GO:0005509	calcium ion binding
0.48	GO:0043237	laminin-1 binding
0.43	GO:0005539	glycosaminoglycan binding
0.40	GO:0008270	zinc ion binding
0.36	GO:0016015	morphogen activity
0.34	GO:0019901	protein kinase binding
0.34	GO:0022857	transmembrane transporter activity

0.66	GO:0044421	extracellular region part
0.52	GO:0005886	plasma membrane
0.44	GO:0098857	membrane microdomain
0.43	GO:0009986	cell surface
0.35	GO:0005634	nucleus
0.34	GO:0005783	endoplasmic reticulum
0.34	GO:0008021	synaptic vesicle
0.34	GO:0043025	neuronal cell body
0.34	GO:0030425	dendrite
0.34	GO:0030424	axon

0.60

GO:0008233

sp|Q14624|ITIH4_HUMAN
Inter-alpha-trypsin inhibitor heavy chain H4
Search

ITIH4

0.91	Inter-alpha-trypsin inhibitor heavy chain 3

0.84	GO:0030212	hyaluronan metabolic process
0.74	GO:0010951	negative regulation of endopeptidase activity
0.59	GO:0006953	acute-phase response
0.54	GO:0034097	response to cytokine
0.38	GO:0002576	platelet degranulation

0.77	GO:0004867	serine-type endopeptidase inhibitor activity
0.40	GO:0005540	hyaluronic acid binding
0.37	GO:0005509	calcium ion binding
0.36	GO:0005515	protein binding

0.41	GO:0072562	blood microparticle
0.40	GO:0070062	extracellular exosome
0.39	GO:0031089	platelet dense granule lumen
0.36	GO:0005886	plasma membrane

sp|Q14626|I11RA_HUMAN
Interleukin-11 receptor subunit alpha
Search

IL11RA

0.97	Interleukin-11 receptor subunit alpha

0.78	GO:0019221	cytokine-mediated signaling pathway
0.57	GO:0060322	head development
0.44	GO:0033499	galactose catabolic process via UDP-galactose
0.43	GO:0007565	female pregnancy
0.40	GO:0001779	natural killer cell differentiation
0.39	GO:0001890	placenta development
0.38	GO:0008284	positive regulation of cell proliferation
0.38	GO:0048609	multicellular organismal reproductive process
0.37	GO:0009888	tissue development

0.80	GO:0004896	cytokine receptor activity
0.44	GO:0008108	UDP-glucose:hexose-1-phosphate uridylyltransferase activity
0.40	GO:0019970	interleukin-11 binding
0.39	GO:0008270	zinc ion binding
0.35	GO:0046982	protein heterodimerization activity

0.35

GO:0005887

integral component of plasma membrane

0.44	EC:2.7.7.12	GO:0008108
0.44	KEGG:R00955	GO:0008108

sp|Q14627|I13R2_HUMAN
Interleukin-13 receptor subunit alpha-2
Search

IL13RA2

0.97	Interleukin-13 receptor subunit alpha-2

0.72	GO:0019221	cytokine-mediated signaling pathway
0.69	GO:0043305	negative regulation of mast cell degranulation
0.68	GO:0002638	negative regulation of immunoglobulin production
0.64	GO:0016064	immunoglobulin mediated immune response
0.37	GO:0071260	cellular response to mechanical stimulus
0.34	GO:0032609	interferon-gamma production
0.33	GO:0032729	positive regulation of interferon-gamma production
0.33	GO:0032496	response to lipopolysaccharide
0.33	GO:0018108	peptidyl-tyrosine phosphorylation

0.74	GO:0004896	cytokine receptor activity
0.36	GO:0005515	protein binding

0.38	GO:0005576	extracellular region
0.33	GO:0009897	external side of plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q14641|INSL4_HUMAN
Early placenta insulin-like peptide
Search

sp|Q14642|I5P1_HUMAN
Type I inositol 1,4,5-trisphosphate 5-phosphatase
Search

INPP5A

0.92	Inositol polyphosphate-5-phosphatase A

0.80	GO:0046856	phosphatidylinositol dephosphorylation
0.50	GO:0046855	inositol phosphate dephosphorylation
0.49	GO:0048016	inositol phosphate-mediated signaling

0.57	GO:0042731	PH domain binding
0.55	GO:0004445	inositol-polyphosphate 5-phosphatase activity
0.40	GO:0052659	inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity
0.40	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity

0.37	GO:0070062	extracellular exosome
0.35	GO:0005622	intracellular
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.55	EC:3.1.3.56	GO:0004445
0.40	KEGG:R03430	GO:0052659

sp|Q14643|ITPR1_HUMAN
Inositol 1,4,5-trisphosphate receptor type 1
Search

ITPR1

0.93	'Inositol 1,4,5-trisphosphate receptor type 1'

0.85	GO:0048016	inositol phosphate-mediated signaling
0.76	GO:0070588	calcium ion transmembrane transport
0.56	GO:0050882	voluntary musculoskeletal movement
0.55	GO:0051283	negative regulation of sequestering of calcium ion
0.55	GO:0042045	epithelial fluid transport
0.55	GO:0060402	calcium ion transport into cytosol
0.55	GO:0050849	negative regulation of calcium-mediated signaling
0.54	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
0.54	GO:0032469	endoplasmic reticulum calcium ion homeostasis
0.52	GO:0001666	response to hypoxia

0.85	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
0.85	GO:0070679	inositol 1,4,5 trisphosphate binding
0.56	GO:0019855	calcium channel inhibitor activity
0.49	GO:0035091	phosphatidylinositol binding
0.43	GO:0005509	calcium ion binding
0.36	GO:0005515	protein binding
0.34	GO:0044877	macromolecular complex binding

0.70	GO:0005783	endoplasmic reticulum
0.57	GO:0031088	platelet dense granule membrane
0.56	GO:0031094	platelet dense tubular network
0.55	GO:0005955	calcineurin complex
0.53	GO:0016528	sarcoplasm
0.52	GO:0014069	postsynaptic density
0.52	GO:0005637	nuclear inner membrane
0.48	GO:0005730	nucleolus
0.47	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.46	GO:0031984	organelle subcompartment

sp|Q14644|RASA3_HUMAN
Ras GTPase-activating protein 3
Search

RASA3

0.97	Ras GTPase-activating protein 3

0.80	GO:0046580	negative regulation of Ras protein signal transduction
0.74	GO:0043087	regulation of GTPase activity
0.72	GO:0051345	positive regulation of hydrolase activity
0.61	GO:0035556	intracellular signal transduction
0.56	GO:0051209	release of sequestered calcium ion into cytosol
0.48	GO:0043363	nucleate erythrocyte differentiation
0.47	GO:0002574	thrombocyte differentiation
0.37	GO:0034605	cellular response to heat
0.34	GO:0023014	signal transduction by protein phosphorylation

0.74	GO:0005096	GTPase activator activity
0.56	GO:0015278	calcium-release channel activity
0.40	GO:0005543	phospholipid binding
0.35	GO:0046872	metal ion binding

0.58	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane
0.44	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|Q14651|PLSI_HUMAN
Plastin-1
Search

PLS1

0.88	Plastin-1 isoform A

0.58	GO:1902896	terminal web assembly
0.58	GO:0001951	intestinal D-glucose absorption
0.58	GO:0032532	regulation of microvillus length
0.55	GO:0040018	positive regulation of multicellular organism growth
0.55	GO:1903078	positive regulation of protein localization to plasma membrane
0.50	GO:0051639	actin filament network formation
0.49	GO:0051764	actin crosslink formation
0.49	GO:0051017	actin filament bundle assembly
0.43	GO:0060348	bone development
0.40	GO:0071803	positive regulation of podosome assembly

0.74	GO:0003779	actin binding
0.69	GO:0005509	calcium ion binding
0.66	GO:0032403	protein complex binding
0.38	GO:0050839	cell adhesion molecule binding
0.37	GO:0051020	GTPase binding
0.37	GO:0042802	identical protein binding
0.37	GO:0005102	receptor binding
0.34	GO:0005200	structural constituent of cytoskeleton
0.34	GO:0005262	calcium channel activity

0.57	GO:1990357	terminal web
0.54	GO:0005903	brush border
0.49	GO:0032432	actin filament bundle
0.49	GO:0005884	actin filament
0.41	GO:0005829	cytosol
0.39	GO:0001891	phagocytic cup
0.39	GO:0002102	podosome
0.39	GO:0098858	actin-based cell projection
0.39	GO:0042641	actomyosin
0.39	GO:0001726	ruffle

sp|Q14653|IRF3_HUMAN
Interferon regulatory factor 3
Search

IRF3

0.93	Interferon regulatory factor 3

0.65	GO:0045351	type I interferon biosynthetic process
0.64	GO:0060340	positive regulation of type I interferon-mediated signaling pathway
0.63	GO:0032727	positive regulation of interferon-alpha production
0.63	GO:0032728	positive regulation of interferon-beta production
0.62	GO:0097300	programmed necrotic cell death
0.61	GO:0043330	response to exogenous dsRNA
0.61	GO:0031663	lipopolysaccharide-mediated signaling pathway
0.57	GO:0006351	transcription, DNA-templated
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription

0.76	GO:0044212	transcription regulatory region DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0042803	protein homodimerization activity
0.55	GO:1990837	sequence-specific double-stranded DNA binding
0.54	GO:0019904	protein domain specific binding
0.36	GO:0003712	transcription cofactor activity

0.60	GO:0005634	nucleus
0.51	GO:0005829	cytosol
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0044446	intracellular organelle part
0.32	GO:0048471	perinuclear region of cytoplasm

sp|Q14654|KCJ11_HUMAN
ATP-sensitive inward rectifier potassium channel 11
Search

KCNJ11

0.96	ATP-sensitive inward rectifier potassium channel

0.78	GO:0034765	regulation of ion transmembrane transport
0.71	GO:0006813	potassium ion transport
0.61	GO:0098655	cation transmembrane transport
0.58	GO:0042391	regulation of membrane potential
0.57	GO:0014070	response to organic cyclic compound
0.57	GO:1901698	response to nitrogen compound
0.55	GO:0046676	negative regulation of insulin secretion
0.55	GO:1901700	response to oxygen-containing compound
0.55	GO:0003008	system process
0.54	GO:0046683	response to organophosphorus

0.86	GO:0015272	ATP-activated inward rectifier potassium channel activity
0.56	GO:0030506	ankyrin binding
0.54	GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization
0.54	GO:0044325	ion channel binding
0.40	GO:0017098	sulfonylurea receptor binding
0.39	GO:0030554	adenyl nucleotide binding
0.39	GO:0097367	carbohydrate derivative binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0008144	drug binding
0.39	GO:0008022	protein C-terminus binding

0.59	GO:0008282	inward rectifying potassium channel
0.50	GO:0042383	sarcolemma
0.50	GO:0030016	myofibril
0.40	GO:0070852	cell body fiber
0.39	GO:0030673	axolemma
0.39	GO:0014704	intercalated disc
0.39	GO:0001669	acrosomal vesicle
0.39	GO:0043209	myelin sheath
0.38	GO:0043025	neuronal cell body
0.38	GO:0005635	nuclear envelope

sp|Q14656|TM187_HUMAN
Transmembrane protein 187
Search

TMEM187

0.94	LOW QUALITY PROTEIN: transmembrane protein 187

0.62	GO:0030133	transport vesicle
0.30	GO:0044425	membrane part

sp|Q14657|LAGE3_HUMAN
EKC/KEOPS complex subunit LAGE3
Search

LAGE3

0.89	L antigen family member 3

0.38

GO:0030225

macrophage differentiation

0.83	GO:0000408	EKC/KEOPS complex
0.77	GO:0016604	nuclear body

sp|Q14667|K0100_HUMAN
Protein KIAA0100
Search

0.37

GO:0006468

protein phosphorylation

0.43	GO:0005515	protein binding
0.37	GO:0004672	protein kinase activity
0.36	GO:0030554	adenyl nucleotide binding
0.35	GO:0097367	carbohydrate derivative binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.51	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

sp|Q14669|TRIPC_HUMAN
E3 ubiquitin-protein ligase TRIP12
Search

TRIP12

0.66	E3 ubiquitin-protein ligase TRIP12 isoform C

0.72	GO:0016567	protein ubiquitination
0.48	GO:0045995	regulation of embryonic development
0.45	GO:1901314	regulation of histone H2A K63-linked ubiquitination
0.45	GO:0033183	negative regulation of histone ubiquitination
0.45	GO:1900045	negative regulation of protein K63-linked ubiquitination
0.43	GO:2000780	negative regulation of double-strand break repair
0.40	GO:0006511	ubiquitin-dependent protein catabolic process
0.38	GO:0006974	cellular response to DNA damage stimulus
0.37	GO:0006259	DNA metabolic process
0.35	GO:0043043	peptide biosynthetic process

0.73	GO:0004842	ubiquitin-protein transferase activity
0.59	GO:0016874	ligase activity
0.51	GO:0008270	zinc ion binding
0.42	GO:0046966	thyroid hormone receptor binding
0.40	GO:0061659	ubiquitin-like protein ligase activity
0.35	GO:0003735	structural constituent of ribosome

0.40	GO:0016607	nuclear speck
0.37	GO:0005829	cytosol
0.35	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

0.59	EC:6	GO:0016874
0.73	KEGG:R03876	GO:0004842

sp|Q14671|PUM1_HUMAN
Pumilio homolog 1
Search

PUM1

0.97	Pumilio like protein 1

0.58	GO:1900246	positive regulation of RIG-I signaling pathway
0.57	GO:2000637	positive regulation of gene silencing by miRNA
0.56	GO:0061157	mRNA destabilization
0.55	GO:0035196	production of miRNAs involved in gene silencing by miRNA
0.54	GO:0008344	adult locomotory behavior
0.54	GO:0048863	stem cell differentiation
0.53	GO:0007283	spermatogenesis
0.52	GO:0051983	regulation of chromosome segregation
0.49	GO:0051726	regulation of cell cycle

0.59	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.54	GO:0000932	P-body
0.53	GO:0016607	nuclear speck
0.53	GO:0010494	cytoplasmic stress granule
0.48	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

sp|Q14674|ESPL1_HUMAN
Separin
Search

ESPL1

0.82	Extra spindle pole bodies like 1, separase

0.66	GO:0000212	meiotic spindle organization
0.63	GO:0045143	homologous chromosome segregation
0.61	GO:0000070	mitotic sister chromatid segregation
0.61	GO:0006508	proteolysis
0.54	GO:0051307	meiotic chromosome separation
0.39	GO:0045875	negative regulation of sister chromatid cohesion
0.39	GO:0045842	positive regulation of mitotic metaphase/anaphase transition
0.38	GO:0040001	establishment of mitotic spindle localization
0.38	GO:0000281	mitotic cytokinesis
0.37	GO:0006915	apoptotic process

0.61	GO:0008233	peptidase activity
0.36	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.61	GO:0005813	centrosome
0.52	GO:0072686	mitotic spindle
0.38	GO:0005737	cytoplasm
0.34	GO:0016272	prefoldin complex

0.61

GO:0008233

sp|Q14676|MDC1_HUMAN
Mediator of DNA damage checkpoint protein 1
Search

MDC1

0.64	Mediator of DNA damage checkpoint protein 1

0.43	GO:0007049	cell cycle
0.43	GO:0006281	DNA repair
0.37	GO:0006955	immune response
0.36	GO:0006898	receptor-mediated endocytosis
0.36	GO:0048523	negative regulation of cellular process
0.36	GO:0042981	regulation of apoptotic process
0.36	GO:0007346	regulation of mitotic cell cycle
0.34	GO:0006508	proteolysis
0.33	GO:0006468	protein phosphorylation

0.87	GO:0070975	FHA domain binding
0.79	GO:0008022	protein C-terminus binding
0.38	GO:0005044	scavenger receptor activity
0.37	GO:0001871	pattern binding
0.36	GO:0030246	carbohydrate binding
0.36	GO:0004198	calcium-dependent cysteine-type endopeptidase activity
0.35	GO:0005509	calcium ion binding
0.33	GO:0004674	protein serine/threonine kinase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding

0.77	GO:0005925	focal adhesion
0.74	GO:0016604	nuclear body
0.44	GO:0005694	chromosome
0.34	GO:0031012	extracellular matrix
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0004674

sp|Q14677|EPN4_HUMAN
Clathrin interactor 1
Search

CLINT1

0.95	LOW QUALITY PROTEIN: clathrin interactor 1

0.69	GO:0016192	vesicle-mediated transport
0.37	GO:0045682	regulation of epidermis development
0.37	GO:0048268	clathrin coat assembly
0.36	GO:0098657	import into cell

0.55	GO:0045296	cadherin binding
0.54	GO:0030276	clathrin binding
0.36	GO:0008289	lipid binding

0.72	GO:0005794	Golgi apparatus
0.49	GO:0005654	nucleoplasm
0.39	GO:0030136	clathrin-coated vesicle
0.37	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0005798	Golgi-associated vesicle
0.34	GO:0031984	organelle subcompartment
0.31	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|Q14678|KANK1_HUMAN
KN motif and ankyrin repeat domain-containing protein 1
Search

KANK1

0.80	KN motif and ankyrin repeat domain-containing protein 1

0.88	GO:2000393	negative regulation of lamellipodium morphogenesis
0.87	GO:1900028	negative regulation of ruffle assembly
0.86	GO:0035413	positive regulation of catenin import into nucleus
0.86	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading
0.86	GO:0035024	negative regulation of Rho protein signal transduction
0.85	GO:0046627	negative regulation of insulin receptor signaling pathway
0.85	GO:0090303	positive regulation of wound healing
0.85	GO:0010977	negative regulation of neuron projection development
0.84	GO:0030177	positive regulation of Wnt signaling pathway
0.83	GO:0030336	negative regulation of cell migration

0.84

GO:0008013

beta-catenin binding

0.85	GO:0032587	ruffle membrane
0.48	GO:0005634	nucleus
0.41	GO:0005737	cytoplasm

sp|Q14679|TTLL4_HUMAN
Tubulin polyglutamylase TTLL4
Search

TTLL4

0.90	Tubulin tyrosine ligase like 4

0.85

GO:0018095

protein polyglutamylation

0.74	GO:0070739	protein-glutamic acid ligase activity
0.62	GO:0015631	tubulin binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding

0.74

EC:6.3.2

GO:0070739

sp|Q14680|MELK_HUMAN
Maternal embryonic leucine zipper kinase
Search

MELK

0.60	Non-specific serine/threonine protein kinase

0.61	GO:0006468	protein phosphorylation
0.56	GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress
0.54	GO:0061351	neural precursor cell proliferation
0.52	GO:0018212	peptidyl-tyrosine modification
0.51	GO:0043065	positive regulation of apoptotic process
0.42	GO:0048821	erythrocyte development
0.41	GO:0008016	regulation of heart contraction
0.33	GO:0043066	negative regulation of apoptotic process

0.68	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0005509	calcium ion binding

0.50	GO:0005938	cell cortex
0.41	GO:0005886	plasma membrane
0.40	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0004674

sp|Q14681|KCTD2_HUMAN
BTB/POZ domain-containing protein KCTD2
Search

KCTD2

0.91	Potassium channel tetramerization domain containing 2

0.78	GO:0051260	protein homooligomerization
0.52	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process

0.62	GO:0032403	protein complex binding
0.58	GO:0097602	cullin family protein binding
0.43	GO:0042802	identical protein binding

0.55	GO:0031463	Cul3-RING ubiquitin ligase complex
0.41	GO:0005829	cytosol

sp|Q14683|SMC1A_HUMAN
Structural maintenance of chromosomes protein 1A
Search

0.10	Putative structural maintenance (Fragment)

0.82	GO:0007064	mitotic sister chromatid cohesion
0.65	GO:0006281	DNA repair
0.58	GO:0072423	response to DNA damage checkpoint signaling
0.57	GO:0032876	negative regulation of DNA endoreduplication
0.56	GO:1901673	regulation of mitotic spindle assembly
0.54	GO:0019827	stem cell population maintenance
0.52	GO:0051321	meiotic cell cycle
0.51	GO:0009314	response to radiation
0.38	GO:0051301	cell division
0.37	GO:0048731	system development

0.77	GO:0003682	chromatin binding
0.56	GO:0036033	mediator complex binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0046982	protein heterodimerization activity
0.34	GO:0003723	RNA binding

0.84	GO:0008278	cohesin complex
0.57	GO:0005634	nucleus
0.56	GO:0097431	mitotic spindle pole
0.53	GO:0000776	kinetochore
0.47	GO:0031974	membrane-enclosed lumen
0.47	GO:0005829	cytosol
0.35	GO:0000779	condensed chromosome, centromeric region
0.30	GO:0016020	membrane

sp|Q14684|RRP1B_HUMAN
Ribosomal RNA processing protein 1 homolog B
Search

RRP1B

0.96	Ribosomal RNA processing protein 1 like protein B

0.67	GO:0006364	rRNA processing
0.62	GO:0043923	positive regulation by host of viral transcription
0.59	GO:0098586	cellular response to virus
0.57	GO:0010923	negative regulation of phosphatase activity
0.56	GO:0043065	positive regulation of apoptotic process
0.54	GO:0006366	transcription by RNA polymerase II
0.54	GO:0045944	positive regulation of transcription by RNA polymerase II
0.53	GO:0034260	negative regulation of GTPase activity
0.50	GO:0043484	regulation of RNA splicing
0.38	GO:0006915	apoptotic process

0.60	GO:0001105	RNA polymerase II transcription coactivator activity
0.35	GO:0005515	protein binding
0.35	GO:0003723	RNA binding
0.35	GO:0008478	pyridoxal kinase activity

0.82	GO:0030688	preribosome, small subunit precursor
0.62	GO:0001652	granular component
0.51	GO:0000791	euchromatin
0.50	GO:0000792	heterochromatin
0.49	GO:0030687	preribosome, large subunit precursor
0.36	GO:0005654	nucleoplasm
0.36	GO:0005829	cytosol

0.35

EC:2.7.1.35

GO:0008478

sp|Q14686|NCOA6_HUMAN
Nuclear receptor coactivator 6
Search

NCOA6

0.91	LOW QUALITY PROTEIN: nuclear receptor coactivator 6

0.57	GO:2001141	regulation of RNA biosynthetic process
0.53	GO:0030099	myeloid cell differentiation
0.50	GO:0051254	positive regulation of RNA metabolic process
0.49	GO:0010557	positive regulation of macromolecule biosynthetic process
0.49	GO:0031328	positive regulation of cellular biosynthetic process
0.49	GO:0010628	positive regulation of gene expression
0.47	GO:0006352	DNA-templated transcription, initiation
0.45	GO:0006974	cellular response to DNA damage stimulus
0.43	GO:0009725	response to hormone
0.42	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.79	GO:0003713	transcription coactivator activity
0.56	GO:0046966	thyroid hormone receptor binding
0.48	GO:0019899	enzyme binding
0.35	GO:0046965	retinoid X receptor binding
0.35	GO:0035258	steroid hormone receptor binding
0.35	GO:0042975	peroxisome proliferator activated receptor binding
0.35	GO:0016922	ligand-dependent nuclear receptor binding
0.34	GO:0003682	chromatin binding
0.34	GO:0019904	protein domain specific binding
0.34	GO:0042803	protein homodimerization activity

0.61	GO:0005634	nucleus
0.52	GO:0034708	methyltransferase complex
0.47	GO:0031974	membrane-enclosed lumen
0.46	GO:0005829	cytosol
0.43	GO:0005667	transcription factor complex
0.43	GO:0044446	intracellular organelle part
0.32	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.32	GO:0005783	endoplasmic reticulum
0.30	GO:0031224	intrinsic component of membrane

sp|Q14687|GSE1_HUMAN
Genetic suppressor element 1
Search

GSE1

0.94	Genetic suppressor element 1

0.50	GO:0005515	protein binding
0.46	GO:0008270	zinc ion binding

0.37	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|Q14689|DIP2A_HUMAN
Disco-interacting protein 2 homolog A
Search

DIP2A

0.97	Disco-interacting protein 2 like protein A

0.50	GO:0042981	regulation of apoptotic process
0.47	GO:0010629	negative regulation of gene expression
0.35	GO:0007275	multicellular organism development
0.30	GO:0008152	metabolic process

0.33	GO:0005515	protein binding
0.30	GO:0003824	catalytic activity

0.51	GO:0009986	cell surface
0.34	GO:0005634	nucleus

sp|Q14690|RRP5_HUMAN
Protein RRP5 homolog
Search

PDCD11

0.89	Tetratricopeptide repeat protein 29

0.67	GO:0006397	mRNA processing
0.51	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.51	GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.33	GO:0032981	mitochondrial respiratory chain complex I assembly

0.56	GO:0008134	transcription factor binding
0.51	GO:0003676	nucleic acid binding

0.59	GO:0005634	nucleus
0.54	GO:0005829	cytosol
0.50	GO:0032040	small-subunit processome
0.45	GO:0031974	membrane-enclosed lumen
0.42	GO:0043232	intracellular non-membrane-bounded organelle
0.41	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|Q14691|PSF1_HUMAN
DNA replication complex GINS protein PSF1
Search

GINS1

0.86	DNA replication complex GINS protein PSF1

0.66	GO:0006260	DNA replication
0.54	GO:0001833	inner cell mass cell proliferation
0.48	GO:0022616	DNA strand elongation
0.46	GO:0032392	DNA geometric change
0.46	GO:1903047	mitotic cell cycle process
0.42	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle
0.32	GO:0051225	spindle assembly
0.32	GO:0000280	nuclear division
0.32	GO:0007018	microtubule-based movement
0.32	GO:0007059	chromosome segregation

0.50	GO:0043138	3'-5' DNA helicase activity
0.34	GO:0003682	chromatin binding
0.34	GO:0005515	protein binding
0.33	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed
0.31	GO:0030554	adenyl nucleotide binding
0.31	GO:0032555	purine ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.85	GO:0000811	GINS complex
0.38	GO:0005737	cytoplasm
0.32	GO:0005871	kinesin complex

0.33

EC:3.6.4.4

GO:0008574

sp|Q14692|BMS1_HUMAN
Ribosome biogenesis protein BMS1 homolog
Search

BMS1

0.84	Ribosome biogenesis protein BMS1

0.66	GO:0042254	ribosome biogenesis
0.47	GO:0016072	rRNA metabolic process
0.46	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.45	GO:0034470	ncRNA processing
0.43	GO:0031016	pancreas development
0.43	GO:0001889	liver development

0.64	GO:0032550	purine ribonucleoside binding
0.64	GO:0019001	guanyl nucleotide binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0034511	U3 snoRNA binding
0.45	GO:0003924	GTPase activity
0.35	GO:0005515	protein binding
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0008144	drug binding
0.32	GO:0003677	DNA binding

0.60	GO:0005634	nucleus
0.50	GO:0030686	90S preribosome
0.48	GO:0031974	membrane-enclosed lumen
0.44	GO:0043232	intracellular non-membrane-bounded organelle
0.43	GO:0044446	intracellular organelle part

sp|Q14693|LPIN1_HUMAN
Phosphatidate phosphatase LPIN1
Search

LPIN1

0.88	Phosphatidate phosphatase LPIN1

0.82	GO:0019432	triglyceride biosynthetic process
0.76	GO:0009062	fatty acid catabolic process
0.70	GO:0006357	regulation of transcription by RNA polymerase II
0.68	GO:0016311	dephosphorylation
0.42	GO:0045893	positive regulation of transcription, DNA-templated
0.38	GO:0007077	mitotic nuclear envelope disassembly
0.38	GO:0006642	triglyceride mobilization
0.38	GO:0031100	animal organ regeneration
0.37	GO:0032869	cellular response to insulin stimulus
0.37	GO:0006656	phosphatidylcholine biosynthetic process

0.85	GO:0008195	phosphatidate phosphatase activity
0.44	GO:0003713	transcription coactivator activity

0.43	GO:0005741	mitochondrial outer membrane
0.39	GO:0005634	nucleus
0.36	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0005829	cytosol
0.35	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

0.85

EC:3.1.3.4

GO:0008195

sp|Q14694|UBP10_HUMAN
Ubiquitin carboxyl-terminal hydrolase 10
Search

USP10

0.94	Ubiquitin carboxyl-terminal hydrolase 10

0.75	GO:0016579	protein deubiquitination
0.70	GO:0006511	ubiquitin-dependent protein catabolic process
0.60	GO:0030330	DNA damage response, signal transduction by p53 class mediator
0.58	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling
0.58	GO:0071347	cellular response to interleukin-1
0.53	GO:0010506	regulation of autophagy
0.42	GO:0006914	autophagy
0.39	GO:0006281	DNA repair
0.34	GO:0071897	DNA biosynthetic process

0.75	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.58	GO:0002039	p53 binding
0.57	GO:0044325	ion channel binding
0.53	GO:0004197	cysteine-type endopeptidase activity
0.34	GO:0003723	RNA binding

0.56	GO:0005769	early endosome
0.49	GO:0005654	nucleoplasm
0.48	GO:0005829	cytosol
0.44	GO:0043234	protein complex

0.75

EC:3.4.19.12

GO:0036459

sp|Q14695|K0087_HUMAN
Uncharacterized protein KIAA0087
Search

sp|Q14696|MESD_HUMAN
LDLR chaperone MESD
Search

MESD

0.91	LDLR chaperone MESD

0.69	GO:0006457	protein folding
0.55	GO:1904395	positive regulation of skeletal muscle acetylcholine-gated channel clustering
0.52	GO:0034394	protein localization to cell surface
0.50	GO:0006909	phagocytosis
0.46	GO:0016055	Wnt signaling pathway
0.41	GO:0007498	mesoderm development

0.51	GO:0050750	low-density lipoprotein particle receptor binding
0.46	GO:0042802	identical protein binding
0.33	GO:0003676	nucleic acid binding

0.44	GO:0005783	endoplasmic reticulum
0.39	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q14697|GANAB_HUMAN
Neutral alpha-glucosidase AB
Search

GANAB

0.79	Neutral alpha-glucosidase AB

0.60	GO:0005975	carbohydrate metabolic process
0.36	GO:0009100	glycoprotein metabolic process
0.35	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.34	GO:0043413	macromolecule glycosylation
0.34	GO:0006886	intracellular protein transport
0.34	GO:0006457	protein folding
0.33	GO:1901137	carbohydrate derivative biosynthetic process
0.33	GO:0036211	protein modification process
0.33	GO:0044267	cellular protein metabolic process
0.32	GO:1901566	organonitrogen compound biosynthetic process

0.69	GO:0030246	carbohydrate binding
0.66	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.35	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity
0.34	GO:0008565	protein transporter activity
0.34	GO:0003723	RNA binding
0.33	GO:0005515	protein binding
0.32	GO:0046872	metal ion binding

0.54	GO:0017177	glucosidase II complex
0.40	GO:0042470	melanosome
0.38	GO:0005794	Golgi apparatus
0.37	GO:0031012	extracellular matrix
0.36	GO:0070062	extracellular exosome
0.35	GO:0005788	endoplasmic reticulum lumen
0.34	GO:0098588	bounding membrane of organelle
0.34	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.66

EC:3.2.1

GO:0004553

sp|Q14699|RFTN1_HUMAN
Raftlin
Search

RFTN1

0.97	Raftlin lipid raft linker 1

0.82	GO:0033227	dsRNA transport
0.81	GO:0050851	antigen receptor-mediated signaling pathway
0.81	GO:0034138	toll-like receptor 3 signaling pathway
0.81	GO:0043330	response to exogenous dsRNA
0.80	GO:0001765	membrane raft assembly
0.75	GO:0032596	protein transport into membrane raft
0.72	GO:0040007	growth
0.63	GO:0002457	T cell antigen processing and presentation
0.62	GO:0032620	interleukin-17 production
0.33	GO:0007281	germ cell development

0.71	GO:0003725	double-stranded RNA binding
0.41	GO:0003730	mRNA 3'-UTR binding
0.34	GO:0008494	translation activator activity

0.77	GO:0045121	membrane raft
0.70	GO:0005768	endosome
0.56	GO:0043234	protein complex
0.53	GO:0005886	plasma membrane
0.43	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

sp|Q14703|MBTP1_HUMAN
Membrane-bound transcription factor site-1 protease
Search

MBTPS1

0.94	Membrane-bound transcription factor peptidase site 1 mutant

0.59	GO:0006508	proteolysis
0.56	GO:0042990	regulation of transcription factor import into nucleus
0.56	GO:0007040	lysosome organization
0.48	GO:0006629	lipid metabolic process
0.45	GO:0001889	liver development
0.45	GO:0051216	cartilage development
0.39	GO:1902652	secondary alcohol metabolic process
0.36	GO:0034976	response to endoplasmic reticulum stress
0.36	GO:0045540	regulation of cholesterol biosynthetic process
0.35	GO:0006984	ER-nucleus signaling pathway

0.67	GO:0004252	serine-type endopeptidase activity
0.34	GO:0004222	metalloendopeptidase activity

0.54	GO:0005795	Golgi stack
0.38	GO:0000139	Golgi membrane
0.38	GO:0005789	endoplasmic reticulum membrane
0.37	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0016021	integral component of membrane

0.67

GO:0004252

sp|Q14714|SSPN_HUMAN
Sarcospan
Search

SSPN

0.97	Sarcospan (Kras oncogene-associated gene)

0.36	GO:0006936	muscle contraction
0.35	GO:0007155	cell adhesion

0.84	GO:0016010	dystrophin-associated glycoprotein complex
0.67	GO:0005887	integral component of plasma membrane
0.56	GO:0030133	transport vesicle
0.41	GO:0042383	sarcolemma
0.39	GO:0045211	postsynaptic membrane
0.38	GO:0030054	cell junction

sp|Q14721|KCNB1_HUMAN
Potassium voltage-gated channel subfamily B member 1
Search

KCNB1

0.94	Potassium voltage-gated channel subfamily B member 1

0.74	GO:0034765	regulation of ion transmembrane transport
0.73	GO:0051260	protein homooligomerization
0.73	GO:0071805	potassium ion transmembrane transport
0.66	GO:1900454	positive regulation of long term synaptic depression
0.64	GO:0090314	positive regulation of protein targeting to membrane
0.63	GO:0046676	negative regulation of insulin secretion
0.62	GO:0098900	regulation of action potential
0.62	GO:0001508	action potential
0.61	GO:0071333	cellular response to glucose stimulus
0.49	GO:0010701	positive regulation of norepinephrine secretion

0.78	GO:0005249	voltage-gated potassium channel activity
0.60	GO:0044325	ion channel binding
0.42	GO:0046982	protein heterodimerization activity
0.37	GO:0047485	protein N-terminus binding
0.37	GO:0000149	SNARE binding

0.78	GO:0008076	voltage-gated potassium channel complex
0.63	GO:0032809	neuronal cell body membrane
0.58	GO:0030425	dendrite
0.46	GO:0043204	perikaryon
0.45	GO:0016328	lateral plasma membrane
0.45	GO:0042383	sarcolemma
0.44	GO:0030424	axon
0.44	GO:0045211	postsynaptic membrane
0.42	GO:0030054	cell junction
0.37	GO:0032589	neuron projection membrane

sp|Q14722|KCAB1_HUMAN
Voltage-gated potassium channel subunit beta-1
Search

KCNAB1

0.95	Voltage-gated potassium channel subunit beta-1

0.71	GO:0071805	potassium ion transmembrane transport
0.56	GO:1901379	regulation of potassium ion transmembrane transport
0.54	GO:0043267	negative regulation of potassium ion transport
0.54	GO:2001258	negative regulation of cation channel activity
0.51	GO:0007611	learning or memory
0.45	GO:0048523	negative regulation of cellular process
0.42	GO:0002244	hematopoietic progenitor cell differentiation
0.42	GO:0050905	neuromuscular process
0.40	GO:0045445	myoblast differentiation
0.39	GO:0060539	diaphragm development

0.75	GO:0005249	voltage-gated potassium channel activity
0.58	GO:0015459	potassium channel regulator activity
0.51	GO:0070402	NADPH binding
0.49	GO:0019904	protein domain specific binding
0.43	GO:0004033	aldo-keto reductase (NADP) activity
0.39	GO:0044325	ion channel binding

0.53	GO:0034705	potassium channel complex
0.52	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.48	GO:0005737	cytoplasm
0.47	GO:0005887	integral component of plasma membrane
0.46	GO:0044224	juxtaparanode region of axon
0.42	GO:0043679	axon terminus
0.41	GO:0014069	postsynaptic density
0.39	GO:1990635	proximal dendrite
0.38	GO:0043204	perikaryon
0.38	GO:1990031	pinceau fiber

0.43

GO:0004033

sp|Q14728|MFS10_HUMAN
Major facilitator superfamily domain-containing protein 10
Search

MFSD10

0.94	Major facilitator superfamily domain-containing protein 10

0.58	GO:0043252	sodium-independent organic anion transport
0.55	GO:0055085	transmembrane transport
0.53	GO:0015904	tetracycline transport
0.38	GO:0006915	apoptotic process

0.53

GO:0008493

tetracycline transmembrane transporter activity

0.59	GO:0031526	brush border membrane
0.52	GO:0030659	cytoplasmic vesicle membrane
0.38	GO:0032040	small-subunit processome
0.30	GO:0016021	integral component of membrane

sp|Q14738|2A5D_HUMAN
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform
Search

PPP2R5D

0.60	Serine/threonine protein phosphatase 2A regulatory subunit

0.79	GO:0043666	regulation of phosphoprotein phosphatase activity
0.61	GO:0007165	signal transduction
0.55	GO:0035307	positive regulation of protein dephosphorylation
0.49	GO:0006470	protein dephosphorylation
0.39	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway
0.38	GO:0031952	regulation of protein autophosphorylation
0.38	GO:0010976	positive regulation of neuron projection development
0.37	GO:0071363	cellular response to growth factor stimulus
0.36	GO:0045944	positive regulation of transcription by RNA polymerase II
0.36	GO:0008285	negative regulation of cell proliferation

0.80	GO:0019888	protein phosphatase regulator activity
0.49	GO:0004721	phosphoprotein phosphatase activity
0.36	GO:0005515	protein binding
0.33	GO:0008233	peptidase activity

0.81	GO:0000159	protein phosphatase type 2A complex
0.37	GO:0000775	chromosome, centromeric region
0.36	GO:0005634	nucleus
0.35	GO:0005829	cytosol
0.35	GO:0043233	organelle lumen
0.34	GO:0005794	Golgi apparatus
0.30	GO:0031224	intrinsic component of membrane

0.49

GO:0004721

sp|Q14739|LBR_HUMAN
Lamin-B receptor
Search

LBR

0.95	Lamin-B receptor

0.52	GO:0055114	oxidation-reduction process
0.49	GO:0016126	sterol biosynthetic process
0.38	GO:0008203	cholesterol metabolic process
0.37	GO:1902653	secondary alcohol biosynthetic process
0.36	GO:0042074	cell migration involved in gastrulation
0.34	GO:0000278	mitotic cell cycle
0.34	GO:0045540	regulation of cholesterol biosynthetic process
0.32	GO:0043043	peptide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0010467	gene expression

0.73	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
0.64	GO:0070087	chromo shadow domain binding
0.36	GO:0005521	lamin binding
0.35	GO:0008139	nuclear localization sequence binding
0.35	GO:0003677	DNA binding
0.35	GO:0050661	NADP binding
0.34	GO:0051087	chaperone binding
0.34	GO:0003723	RNA binding
0.33	GO:0003735	structural constituent of ribosome

0.60	GO:0031965	nuclear membrane
0.48	GO:0030176	integral component of endoplasmic reticulum membrane
0.45	GO:0031301	integral component of organelle membrane
0.43	GO:0043235	receptor complex
0.43	GO:0019866	organelle inner membrane
0.35	GO:0005652	nuclear lamina
0.34	GO:0005643	nuclear pore
0.33	GO:0005887	integral component of plasma membrane
0.32	GO:0005840	ribosome

0.73

EC:1.3.1

GO:0016628

sp|Q14746|COG2_HUMAN
Conserved oligomeric Golgi complex subunit 2
Search

COG2

0.92	Component of oligomeric golgi complex 2

0.81	GO:0007030	Golgi organization
0.64	GO:0015031	protein transport
0.56	GO:0006891	intra-Golgi vesicle-mediated transport
0.35	GO:0006888	ER to Golgi vesicle-mediated transport

0.51	GO:0008565	protein transporter activity
0.38	GO:0032403	protein complex binding

0.56	GO:0017119	Golgi transport complex
0.54	GO:0005795	Golgi stack
0.37	GO:0005829	cytosol
0.36	GO:0000139	Golgi membrane
0.35	GO:0005802	trans-Golgi network
0.30	GO:0016021	integral component of membrane

sp|Q14749|GNMT_HUMAN
Glycine N-methyltransferase
Search

GNMT

0.97	Glycine N-methyltransferase

0.63	GO:0032259	methylation
0.57	GO:0051289	protein homotetramerization
0.56	GO:0006111	regulation of gluconeogenesis
0.55	GO:0046500	S-adenosylmethionine metabolic process
0.52	GO:0006555	methionine metabolic process
0.51	GO:0005977	glycogen metabolic process
0.50	GO:0006730	one-carbon metabolic process
0.45	GO:1901052	sarcosine metabolic process
0.43	GO:0070328	triglyceride homeostasis
0.42	GO:0008340	determination of adult lifespan

0.85	GO:0017174	glycine N-methyltransferase activity
0.59	GO:0016594	glycine binding
0.51	GO:0042802	identical protein binding
0.41	GO:0052729	dimethylglycine N-methyltransferase activity
0.40	GO:0052730	sarcosine N-methyltransferase activity
0.40	GO:0005542	folic acid binding
0.36	GO:0098603	selenol Se-methyltransferase activity
0.34	GO:1904047	S-adenosyl-L-methionine binding
0.33	GO:0030145	manganese ion binding
0.32	GO:0003723	RNA binding

0.49	GO:0005829	cytosol
0.34	GO:0034708	methyltransferase complex
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.85	EC:2.1.1.156 EC:2.1.1.162 EC:2.1.1.20	GO:0017174
0.85	KEGG:R00367	GO:0017174

sp|Q14761|PTCA_HUMAN
Protein tyrosine phosphatase receptor type C-associated protein
Search

PTPRCAP

0.97	Protein tyrosine phosphatase receptor type C-associated protein (Fragment)

0.51

GO:0006952

defense response

0.51	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q14764|MVP_HUMAN
Major vault protein
Search

MVP

0.88	major vault protein isoform X2

0.51	GO:0031953	negative regulation of protein autophosphorylation
0.50	GO:0061099	negative regulation of protein tyrosine kinase activity
0.49	GO:0038127	ERBB signaling pathway
0.48	GO:0023051	regulation of signaling
0.39	GO:0031102	neuron projection regeneration
0.38	GO:0001654	eye development
0.38	GO:0007420	brain development
0.30	GO:0051236	establishment of RNA localization
0.30	GO:0001775	cell activation
0.30	GO:0002443	leukocyte mediated immunity

0.48	GO:0019903	protein phosphatase binding
0.46	GO:0019901	protein kinase binding
0.45	GO:0042802	identical protein binding

0.61	GO:0030529	intracellular ribonucleoprotein complex
0.49	GO:0005737	cytoplasm
0.46	GO:0005634	nucleus
0.43	GO:0005856	cytoskeleton
0.30	GO:0044422	organelle part
0.30	GO:0043234	protein complex
0.30	GO:0016020	membrane
0.30	GO:0043230	extracellular organelle
0.30	GO:0031974	membrane-enclosed lumen
0.30	GO:0005615	extracellular space

sp|Q14765|STAT4_HUMAN
Signal transducer and activator of transcription 4
Search

STAT4

0.69	Signal transducer and activator of transcription

0.75	GO:0019221	cytokine-mediated signaling pathway
0.71	GO:0045944	positive regulation of transcription by RNA polymerase II
0.55	GO:0006351	transcription, DNA-templated
0.46	GO:0007259	JAK-STAT cascade
0.44	GO:0001937	negative regulation of endothelial cell proliferation
0.44	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling
0.44	GO:0046725	negative regulation by virus of viral protein levels in host cell
0.44	GO:0071346	cellular response to interferon-gamma
0.44	GO:0010742	macrophage derived foam cell differentiation
0.44	GO:0072001	renal system development

0.63	GO:0004871	signal transducer activity
0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0003677	DNA binding
0.50	GO:0042802	identical protein binding
0.42	GO:0035035	histone acetyltransferase binding
0.42	GO:1990841	promoter-specific chromatin binding
0.42	GO:0070491	repressing transcription factor binding
0.41	GO:0035257	nuclear hormone receptor binding
0.41	GO:0001067	regulatory region nucleic acid binding
0.41	GO:0005164	tumor necrosis factor receptor binding

0.61	GO:0005634	nucleus
0.47	GO:0005737	cytoplasm
0.40	GO:0070013	intracellular organelle lumen
0.39	GO:0000785	chromatin
0.37	GO:0030425	dendrite
0.37	GO:0030424	axon
0.36	GO:0043234	protein complex

sp|Q14766|LTBP1_HUMAN
Latent-transforming growth factor beta-binding protein 1
Search

LTBP1

0.86	Latent-transforming growth factor beta-binding protein 1

0.63	GO:0060976	coronary vasculature development
0.63	GO:0035904	aorta development
0.63	GO:0003281	ventricular septum development
0.41	GO:0035583	sequestering of TGFbeta in extracellular matrix
0.41	GO:0071374	cellular response to parathyroid hormone stimulus
0.40	GO:0071305	cellular response to vitamin D
0.40	GO:0036120	cellular response to platelet-derived growth factor stimulus
0.40	GO:0010714	positive regulation of collagen metabolic process
0.40	GO:0032965	regulation of collagen biosynthetic process
0.40	GO:0071260	cellular response to mechanical stimulus

0.70	GO:0005509	calcium ion binding
0.67	GO:0050436	microfibril binding
0.64	GO:0050431	transforming growth factor beta binding
0.41	GO:0005024	transforming growth factor beta-activated receptor activity

0.64	GO:0001527	microfibril
0.56	GO:0005578	proteinaceous extracellular matrix
0.55	GO:0005615	extracellular space
0.47	GO:0043234	protein complex
0.40	GO:0005788	endoplasmic reticulum lumen
0.39	GO:0043025	neuronal cell body
0.39	GO:0030425	dendrite
0.38	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0005739	mitochondrion

sp|Q14767|LTBP2_HUMAN
Latent-transforming growth factor beta-binding protein 2
Search

LTBP2

0.64	Latent-transforming growth factor beta-binding protein 2

0.48	GO:0097435	supramolecular fiber organization
0.43	GO:0060976	coronary vasculature development
0.43	GO:0035904	aorta development
0.42	GO:0003281	ventricular septum development
0.41	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
0.41	GO:0071560	cellular response to transforming growth factor beta stimulus
0.40	GO:0046879	hormone secretion
0.38	GO:0030162	regulation of proteolysis
0.36	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway
0.35	GO:0071694	maintenance of protein location in extracellular region

0.70	GO:0005509	calcium ion binding
0.47	GO:0050431	transforming growth factor beta binding
0.45	GO:0050436	microfibril binding
0.37	GO:0008201	heparin binding
0.36	GO:0005024	transforming growth factor beta-activated receptor activity
0.34	GO:0005178	integrin binding
0.34	GO:0005201	extracellular matrix structural constituent

0.52	GO:0031012	extracellular matrix
0.51	GO:0005615	extracellular space
0.40	GO:0099512	supramolecular fiber
0.37	GO:0043234	protein complex
0.36	GO:1903561	extracellular vesicle
0.34	GO:0005788	endoplasmic reticulum lumen

sp|Q14773|ICAM4_HUMAN
Intercellular adhesion molecule 4
Search

ICAM4

0.97	Intercellular adhesion molecule 4, Landsteiner-Wiener blood group

0.75	GO:0098609	cell-cell adhesion
0.41	GO:0030198	extracellular matrix organization
0.39	GO:0050776	regulation of immune response

0.59

GO:0005178

integrin binding

0.58	GO:0005615	extracellular space
0.50	GO:0005887	integral component of plasma membrane
0.42	GO:0005737	cytoplasm

sp|Q14774|HLX_HUMAN
H2.0-like homeobox protein
Search

HLX

0.97	Hlx-1 transcription factor

0.63	GO:0045629	negative regulation of T-helper 2 cell differentiation
0.63	GO:0045627	positive regulation of T-helper 1 cell differentiation
0.61	GO:0048557	embryonic digestive tract morphogenesis
0.60	GO:0048484	enteric nervous system development
0.60	GO:0046622	positive regulation of organ growth
0.59	GO:0001889	liver development
0.58	GO:0007519	skeletal muscle tissue development
0.56	GO:0008284	positive regulation of cell proliferation
0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.63	GO:0043565	sequence-specific DNA binding
0.34	GO:0005515	protein binding
0.31	GO:0016787	hydrolase activity

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.31

GO:0016787

sp|Q14781|CBX2_HUMAN
Chromobox protein homolog 2
Search

CBX2

0.95	Chromobox protein like protein 2

0.70	GO:0045137	development of primary sexual characteristics
0.67	GO:0000122	negative regulation of transcription by RNA polymerase II
0.40	GO:0016569	covalent chromatin modification
0.38	GO:0016925	protein sumoylation
0.37	GO:0030154	cell differentiation
0.36	GO:0006351	transcription, DNA-templated

0.70	GO:0140034	methylation-dependent protein binding
0.67	GO:0042393	histone binding
0.65	GO:0003682	chromatin binding
0.39	GO:0032183	SUMO binding
0.39	GO:0051219	phosphoprotein binding
0.38	GO:0003727	single-stranded RNA binding
0.37	GO:0044212	transcription regulatory region DNA binding
0.36	GO:0019899	enzyme binding
0.33	GO:0019789	SUMO transferase activity

0.74	GO:0035102	PRC1 complex
0.70	GO:0000791	euchromatin
0.68	GO:0000792	heterochromatin
0.61	GO:0005654	nucleoplasm

sp|Q14789|GOGB1_HUMAN
Golgin subfamily B member 1
Search

GOLGB1

0.79	Golgin subfamily B member 1

0.58	GO:1905793	protein localization to pericentriolar material
0.37	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.37	GO:1903506	regulation of nucleic acid-templated transcription
0.37	GO:0010468	regulation of gene expression
0.34	GO:0007030	Golgi organization
0.33	GO:0006888	ER to Golgi vesicle-mediated transport

0.39	GO:0043565	sequence-specific DNA binding
0.39	GO:0003700	DNA binding transcription factor activity
0.33	GO:0003723	RNA binding
0.32	GO:0005515	protein binding

0.71	GO:0005794	Golgi apparatus
0.53	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.48	GO:0005801	cis-Golgi network
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0031984	organelle subcompartment
0.30	GO:0044425	membrane part

sp|Q14790|CASP8_HUMAN
Caspase-8
Search

CASP8

0.89	Caspase 8, apoptosis-related cysteine peptidase

0.78	GO:0006915	apoptotic process
0.74	GO:0042981	regulation of apoptotic process
0.61	GO:0045651	positive regulation of macrophage differentiation
0.61	GO:0097202	activation of cysteine-type endopeptidase activity
0.59	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling
0.58	GO:0071260	cellular response to mechanical stimulus
0.58	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.57	GO:0034612	response to tumor necrosis factor
0.51	GO:0007166	cell surface receptor signaling pathway
0.51	GO:0051603	proteolysis involved in cellular protein catabolic process

0.75	GO:0004197	cysteine-type endopeptidase activity
0.63	GO:0035877	death effector domain binding
0.59	GO:0097110	scaffold protein binding
0.56	GO:0031625	ubiquitin protein ligase binding
0.52	GO:0042802	identical protein binding
0.51	GO:0004871	signal transducer activity
0.39	GO:0005123	death receptor binding
0.38	GO:0005164	tumor necrosis factor receptor binding
0.37	GO:0032403	protein complex binding
0.36	GO:0046982	protein heterodimerization activity

0.66	GO:0097342	ripoptosome
0.63	GO:0031265	CD95 death-inducing signaling complex
0.51	GO:0005654	nucleoplasm
0.38	GO:0030690	Noc1p-Noc2p complex
0.37	GO:0044297	cell body
0.37	GO:0098857	membrane microdomain
0.37	GO:0043005	neuron projection
0.35	GO:0005741	mitochondrial outer membrane
0.35	GO:0005856	cytoskeleton
0.30	GO:0016021	integral component of membrane

0.75

EC:3.4.22

GO:0004197

sp|Q147U1|ZN846_HUMAN
Zinc finger protein 846
Search

0.47	Zinc finger protein 420

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.37	GO:0006351	transcription, DNA-templated
0.33	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.33	GO:0007186	G-protein coupled receptor signaling pathway

0.51	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.41	GO:0003700	DNA binding transcription factor activity
0.37	GO:0005515	protein binding
0.34	GO:0016746	transferase activity, transferring acyl groups
0.33	GO:0004984	olfactory receptor activity
0.33	GO:0004930	G-protein coupled receptor activity

0.46	GO:0031965	nuclear membrane
0.33	GO:0005737	cytoplasm
0.32	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:2.3

GO:0016746

sp|Q147U7|SMCO1_HUMAN
Single-pass membrane and coiled-coil domain-containing protein 1
Search

SMCO1

0.97	Single-pass membrane and coiled-coil domain-containing protein 1

0.41

GO:0003924

GTPase activity

0.30

GO:0044425

membrane part

sp|Q147X3|NAA30_HUMAN
N-alpha-acetyltransferase 30
Search

NAA30

0.94	N-terminal acetyltransferase C complex catalytic subunit Mak3

0.59

GO:0017196

N-terminal peptidyl-methionine acetylation

0.68	GO:0008080	N-acetyltransferase activity
0.34	GO:0005515	protein binding

0.60	GO:0031417	NatC complex
0.56	GO:0005844	polysome
0.49	GO:0005829	cytosol
0.45	GO:0005634	nucleus

0.68

EC:2.3.1

GO:0008080

sp|Q14802|FXYD3_HUMAN
FXYD domain-containing ion transport regulator 3
Search

FXYD3

0.81	FXYD domain-containing ion transport regulator

0.60	GO:0034220	ion transmembrane transport
0.57	GO:2000649	regulation of sodium ion transmembrane transporter activity
0.49	GO:0050790	regulation of catalytic activity
0.43	GO:0006813	potassium ion transport
0.41	GO:0006814	sodium ion transport
0.40	GO:1903779	regulation of cardiac conduction
0.37	GO:0006821	chloride transport
0.30	GO:0009987	cellular process

0.70	GO:0005216	ion channel activity
0.63	GO:0051117	ATPase binding
0.57	GO:0017080	sodium channel regulator activity
0.38	GO:0015079	potassium ion transmembrane transporter activity
0.37	GO:0015108	chloride transmembrane transporter activity
0.34	GO:0045296	cadherin binding
0.33	GO:0003779	actin binding

0.50	GO:0005789	endoplasmic reticulum membrane
0.47	GO:0005887	integral component of plasma membrane
0.40	GO:0070062	extracellular exosome

sp|Q14807|KIF22_HUMAN
Kinesin-like protein KIF22
Search

0.86	Kinesin-like protein KIF22-A

0.74	GO:0007018	microtubule-based movement
0.57	GO:0007080	mitotic metaphase plate congression
0.56	GO:0006281	DNA repair
0.54	GO:0007062	sister chromatid cohesion
0.37	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.36	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.35	GO:0001966	thigmotaxis
0.35	GO:0021952	central nervous system projection neuron axonogenesis
0.34	GO:0001756	somitogenesis
0.34	GO:0048592	eye morphogenesis

0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0003677	DNA binding
0.43	GO:0016887	ATPase activity
0.32	GO:0003735	structural constituent of ribosome
0.32	GO:0003723	RNA binding

0.71	GO:0005874	microtubule
0.55	GO:0016607	nuclear speck
0.55	GO:0072686	mitotic spindle
0.51	GO:0005871	kinesin complex
0.50	GO:0005829	cytosol
0.49	GO:0000785	chromatin
0.36	GO:0000776	kinetochore
0.32	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.43

GO:0016887

sp|Q14814|MEF2D_HUMAN
Myocyte-specific enhancer factor 2D
Search

MEF2D

0.94	Myocyte enhancer factor 2D transcript variant 3

0.74	GO:0045944	positive regulation of transcription by RNA polymerase II
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:0007512	adult heart development
0.55	GO:0001958	endochondral ossification
0.54	GO:1904707	positive regulation of vascular smooth muscle cell proliferation
0.54	GO:0035914	skeletal muscle cell differentiation
0.54	GO:0002062	chondrocyte differentiation
0.53	GO:0001649	osteoblast differentiation
0.43	GO:0030241	skeletal muscle myosin thick filament assembly
0.42	GO:0060914	heart formation

0.76	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.67	GO:0046983	protein dimerization activity
0.53	GO:0033613	activating transcription factor binding
0.53	GO:0042826	histone deacetylase binding
0.52	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.51	GO:0000987	proximal promoter sequence-specific DNA binding
0.49	GO:0042802	identical protein binding

0.60	GO:0005634	nucleus
0.45	GO:0043233	organelle lumen
0.41	GO:0044446	intracellular organelle part
0.38	GO:0005737	cytoplasm

sp|Q14831|GRM7_HUMAN
Metabotropic glutamate receptor 7
Search

GRM7

0.92	Metabotropic glutamate receptor 7

0.69	GO:0007186	G-protein coupled receptor signaling pathway
0.50	GO:0031279	regulation of cyclase activity
0.49	GO:0007605	sensory perception of sound
0.49	GO:0007215	glutamate receptor signaling pathway
0.47	GO:0007268	chemical synaptic transmission
0.45	GO:0051966	regulation of synaptic transmission, glutamatergic
0.41	GO:0001662	behavioral fear response
0.41	GO:0001661	conditioned taste aversion
0.40	GO:0007614	short-term memory
0.39	GO:0019226	transmission of nerve impulse

0.70	GO:0004930	G-protein coupled receptor activity
0.55	GO:0010855	adenylate cyclase inhibitor activity
0.53	GO:0070905	serine binding
0.49	GO:0008066	glutamate receptor activity
0.46	GO:0005246	calcium channel regulator activity
0.41	GO:0016595	glutamate binding
0.39	GO:0030165	PDZ domain binding
0.39	GO:0005245	voltage-gated calcium channel activity
0.37	GO:0005509	calcium ion binding
0.36	GO:0048306	calcium-dependent protein binding

0.53	GO:0005886	plasma membrane
0.49	GO:0030425	dendrite
0.48	GO:0043235	receptor complex
0.47	GO:0005938	cell cortex
0.44	GO:0098793	presynapse
0.38	GO:0032279	asymmetric synapse
0.37	GO:0030424	axon
0.37	GO:0098794	postsynapse
0.36	GO:0044306	neuron projection terminus
0.35	GO:0005791	rough endoplasmic reticulum

sp|Q14832|GRM3_HUMAN
Metabotropic glutamate receptor 3
Search

GRM3

0.96	Glutamate metabotropic receptor 3

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.55	GO:0007215	glutamate receptor signaling pathway
0.49	GO:0051966	regulation of synaptic transmission, glutamatergic
0.49	GO:0065009	regulation of molecular function
0.37	GO:0019233	sensory perception of pain
0.37	GO:0007268	chemical synaptic transmission
0.36	GO:0030818	negative regulation of cAMP biosynthetic process
0.35	GO:0051930	regulation of sensory perception of pain
0.35	GO:0014047	glutamate secretion

0.72	GO:0004930	G-protein coupled receptor activity
0.59	GO:0005246	calcium channel regulator activity
0.55	GO:0008066	glutamate receptor activity
0.33	GO:0005515	protein binding

0.56	GO:0042734	presynaptic membrane
0.55	GO:0043197	dendritic spine
0.55	GO:0014069	postsynaptic density
0.53	GO:0030424	axon
0.53	GO:0045211	postsynaptic membrane
0.42	GO:0005887	integral component of plasma membrane
0.35	GO:0097449	astrocyte projection
0.35	GO:0048786	presynaptic active zone
0.33	GO:0030054	cell junction
0.31	GO:0005622	intracellular

sp|Q14833|GRM4_HUMAN
Metabotropic glutamate receptor 4
Search

GRM4

0.93	Metabotropic glutamate receptor 4

0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.52	GO:0000187	activation of MAPK activity
0.52	GO:0007215	glutamate receptor signaling pathway
0.49	GO:0051966	regulation of synaptic transmission, glutamatergic
0.37	GO:0007268	chemical synaptic transmission
0.37	GO:0007612	learning
0.37	GO:0043523	regulation of neuron apoptotic process
0.36	GO:0006836	neurotransmitter transport
0.35	GO:0050805	negative regulation of synaptic transmission
0.35	GO:0046903	secretion

0.71	GO:0004930	G-protein coupled receptor activity
0.52	GO:0008066	glutamate receptor activity
0.35	GO:0048306	calcium-dependent protein binding
0.35	GO:0005516	calmodulin binding

0.55	GO:0005886	plasma membrane
0.47	GO:0031410	cytoplasmic vesicle
0.46	GO:0098793	presynapse
0.36	GO:0043005	neuron projection
0.35	GO:0036477	somatodendritic compartment
0.34	GO:0120038	plasma membrane bounded cell projection part
0.30	GO:0016021	integral component of membrane

sp|Q14839|CHD4_HUMAN
Chromodomain-helicase-DNA-binding protein 4
Search

CHD4

0.95	Chromodomain helicase DNA binding protein 4

0.47	GO:0031101	fin regeneration
0.39	GO:0072553	terminal button organization
0.37	GO:0043044	ATP-dependent chromatin remodeling
0.37	GO:0000122	negative regulation of transcription by RNA polymerase II

0.67	GO:0001103	RNA polymerase II repressing transcription factor binding
0.66	GO:0042826	histone deacetylase binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0046872	metal ion binding
0.38	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.38	GO:0031492	nucleosomal DNA binding
0.37	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding

0.67	GO:0090545	CHD-type complex
0.65	GO:0090568	nuclear transcriptional repressor complex
0.64	GO:0000118	histone deacetylase complex
0.61	GO:0005813	centrosome
0.57	GO:0032993	protein-DNA complex
0.49	GO:0043234	protein complex
0.42	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q14847|LASP1_HUMAN
LIM and SH3 domain protein 1
Search

LASP1

0.92	LIM zinc-binding domain-containing Nebulette

0.38	GO:0006811	ion transport
0.36	GO:0055085	transmembrane transport
0.35	GO:0009967	positive regulation of signal transduction
0.35	GO:0071691	cardiac muscle thin filament assembly
0.33	GO:2001141	regulation of RNA biosynthetic process
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.58	GO:0045296	cadherin binding
0.55	GO:0051015	actin filament binding
0.53	GO:0046872	metal ion binding
0.37	GO:0015075	ion transmembrane transporter activity
0.36	GO:0005070	SH3/SH2 adaptor activity
0.34	GO:0031005	filamin binding
0.34	GO:0005523	tropomyosin binding
0.33	GO:0003700	DNA binding transcription factor activity

0.57	GO:0005925	focal adhesion
0.43	GO:0005938	cell cortex
0.41	GO:0005856	cytoskeleton
0.38	GO:0070062	extracellular exosome
0.37	GO:0044446	intracellular organelle part
0.34	GO:0030018	Z disc
0.33	GO:0005634	nucleus

sp|Q14849|STAR3_HUMAN
StAR-related lipid transfer protein 3
Search

STARD3

0.95	StAR related lipid transfer domain containing 3

0.72	GO:0030301	cholesterol transport
0.62	GO:0099044	vesicle tethering to endoplasmic reticulum
0.61	GO:0006701	progesterone biosynthetic process
0.35	GO:0008203	cholesterol metabolic process
0.35	GO:0006839	mitochondrial transport
0.35	GO:0032515	negative regulation of phosphoprotein phosphatase activity
0.33	GO:0007165	signal transduction

0.72	GO:0017127	cholesterol transporter activity
0.71	GO:0015485	cholesterol binding
0.52	GO:0042803	protein homodimerization activity
0.35	GO:0004864	protein phosphatase inhibitor activity

0.68	GO:0005770	late endosome
0.56	GO:0044232	organelle membrane contact site
0.54	GO:0010008	endosome membrane
0.51	GO:0005789	endoplasmic reticulum membrane
0.44	GO:0005739	mitochondrion
0.35	GO:0005765	lysosomal membrane
0.34	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

sp|Q14863|PO6F1_HUMAN
POU domain, class 6, transcription factor 1
Search

0.51	POU domain, class 6, transcription factor 1

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.52	GO:0007275	multicellular organism development
0.39	GO:0031099	regeneration
0.35	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.35	GO:0000904	cell morphogenesis involved in differentiation
0.34	GO:0120036	plasma membrane bounded cell projection organization
0.34	GO:0007608	sensory perception of smell

0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.44	GO:0001067	regulatory region nucleic acid binding
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.44	GO:0015629	actin cytoskeleton
0.42	GO:0031974	membrane-enclosed lumen
0.39	GO:0044446	intracellular organelle part

sp|Q14865|ARI5B_HUMAN
AT-rich interactive domain-containing protein 5B
Search

ARID5B

0.94	AT-rich interactive domain-containing protein 5B

0.58	GO:0060613	fat pad development
0.57	GO:0010761	fibroblast migration
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0030325	adrenal gland development
0.56	GO:0060325	face morphogenesis
0.56	GO:0010468	regulation of gene expression
0.55	GO:0048008	platelet-derived growth factor receptor signaling pathway
0.55	GO:0060021	palate development
0.55	GO:0048644	muscle organ morphogenesis

0.54	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.54	GO:0003677	DNA binding
0.54	GO:0001067	regulatory region nucleic acid binding
0.54	GO:0003713	transcription coactivator activity
0.36	GO:0032452	histone demethylase activity
0.34	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|Q14872|MTF1_HUMAN
Metal regulatory transcription factor 1
Search

MTF1

0.96	Metal response element-binding transcription factor 1

0.62	GO:0046686	response to cadmium ion
0.57	GO:0006366	transcription by RNA polymerase II
0.57	GO:0045944	positive regulation of transcription by RNA polymerase II
0.54	GO:0006979	response to oxidative stress

0.65	GO:0035035	histone acetyltransferase binding
0.61	GO:0001047	core promoter binding
0.61	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.60	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.38	GO:0003725	double-stranded RNA binding
0.36	GO:0003713	transcription coactivator activity
0.34	GO:0046872	metal ion binding

0.53

GO:0005654

nucleoplasm

sp|Q14894|CRYM_HUMAN
Ketimine reductase mu-crystallin
Search

CRYM

0.97	Thiomorpholine-carboxylate dehydrogenase

0.84	GO:0042403	thyroid hormone metabolic process
0.83	GO:0070327	thyroid hormone transport
0.77	GO:0007605	sensory perception of sound
0.74	GO:0000122	negative regulation of transcription by RNA polymerase II
0.45	GO:0055114	oxidation-reduction process
0.39	GO:0033280	response to vitamin D
0.38	GO:0006554	lysine catabolic process
0.37	GO:0006839	mitochondrial transport
0.37	GO:0009725	response to hormone
0.34	GO:0006522	alanine metabolic process

0.85	GO:0070324	thyroid hormone binding
0.77	GO:0003714	transcription corepressor activity
0.71	GO:0042803	protein homodimerization activity
0.66	GO:0050661	NADP binding
0.58	GO:0016639	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
0.57	GO:0047127	thiomorpholine-carboxylate dehydrogenase activity
0.44	GO:0008473	ornithine cyclodeaminase activity
0.39	GO:0005212	structural constituent of eye lens
0.34	GO:0000286	alanine dehydrogenase activity
0.33	GO:0051287	NAD binding

0.66	GO:0005829	cytosol
0.57	GO:0005634	nucleus
0.56	GO:0005739	mitochondrion
0.41	GO:0070062	extracellular exosome
0.39	GO:0031907	microbody lumen
0.38	GO:0044439	peroxisomal part
0.30	GO:0031224	intrinsic component of membrane

0.58	EC:1.4.1	GO:0016639
0.44	KEGG:R00671	GO:0008473

sp|Q14896|MYPC3_HUMAN
Myosin-binding protein C, cardiac-type
Search

MYBPC3

0.93	Mutant cardiac myosin-binding protein C

0.85	GO:0055010	ventricular cardiac muscle tissue morphogenesis
0.63	GO:0071688	striated muscle myosin thick filament assembly
0.61	GO:0045214	sarcomere organization
0.60	GO:0006941	striated muscle contraction
0.58	GO:0003210	cardiac atrium formation
0.56	GO:0003211	cardiac ventricle formation
0.55	GO:0007015	actin filament organization
0.53	GO:0002027	regulation of heart rate

0.84	GO:0032036	myosin heavy chain binding
0.82	GO:0008307	structural constituent of muscle
0.69	GO:0042802	identical protein binding
0.64	GO:0097493	structural molecule activity conferring elasticity
0.63	GO:0051371	muscle alpha-actinin binding
0.56	GO:0051015	actin filament binding

0.85	GO:0005863	striated muscle myosin thick filament
0.84	GO:0097512	cardiac myofibril
0.81	GO:0031672	A band
0.60	GO:0030018	Z disc

sp|Q14914|PTGR1_HUMAN
Prostaglandin reductase 1
Search

PTGR1

0.91	Prostaglandin reductase 1

0.52	GO:0055114	oxidation-reduction process
0.46	GO:0006692	prostanoid metabolic process
0.39	GO:0097327	response to antineoplastic agent
0.36	GO:0006691	leukotriene metabolic process
0.34	GO:0043248	proteasome assembly

0.85	GO:0047522	15-oxoprostaglandin 13-oxidase activity
0.82	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.48	GO:0036132	13-prostaglandin reductase activity
0.37	GO:0036185	13-lipoxin reductase activity
0.37	GO:0097257	leukotriene B4 12-hydroxy dehydrogenase activity
0.34	GO:0032947	protein complex scaffold activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.47	GO:0005737	cytoplasm
0.37	GO:0070062	extracellular exosome
0.33	GO:1905369	endopeptidase complex
0.32	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.85	EC:1.3.1.48	GO:0047522
0.85	KEGG:R04556 KEGG:R04557	GO:0047522

sp|Q14916|NPT1_HUMAN
Sodium-dependent phosphate transport protein 1
Search

0.96	Sodium-dependent phosphate transport protein 1

0.63	GO:0015747	urate transport
0.59	GO:0046415	urate metabolic process
0.58	GO:0035435	phosphate ion transmembrane transport
0.50	GO:0035725	sodium ion transmembrane transport
0.40	GO:1901998	toxin transport
0.39	GO:0015739	sialic acid transport
0.39	GO:0006855	drug transmembrane transport
0.36	GO:0044341	sodium-dependent phosphate transport
0.34	GO:0008643	carbohydrate transport
0.33	GO:0006865	amino acid transport

0.59	GO:0015114	phosphate ion transmembrane transporter activity
0.50	GO:0015296	anion:cation symporter activity
0.49	GO:0015081	sodium ion transmembrane transporter activity
0.42	GO:0015143	urate transmembrane transporter activity
0.41	GO:0019534	toxin transmembrane transporter activity
0.40	GO:0008308	voltage-gated anion channel activity
0.39	GO:0015136	sialic acid transmembrane transporter activity
0.39	GO:0015562	efflux transmembrane transporter activity
0.38	GO:0015238	drug transmembrane transporter activity
0.34	GO:0005351	sugar:proton symporter activity

0.58	GO:0016324	apical plasma membrane
0.47	GO:0005887	integral component of plasma membrane
0.40	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0005765	lysosomal membrane
0.38	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0005829	cytosol
0.34	GO:0030672	synaptic vesicle membrane
0.33	GO:0030054	cell junction

sp|Q14919|NC2A_HUMAN
Dr1-associated corepressor
Search

DRAP1

0.94	DR1-associated protein 1 (Negative cofactor 2 alpha)

0.41	GO:0000122	negative regulation of transcription by RNA polymerase II
0.39	GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly
0.37	GO:0045944	positive regulation of transcription by RNA polymerase II
0.33	GO:0000398	mRNA splicing, via spliceosome

0.74	GO:0046982	protein heterodimerization activity
0.50	GO:0042802	identical protein binding
0.40	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly
0.39	GO:0008134	transcription factor binding
0.39	GO:0003714	transcription corepressor activity
0.35	GO:0003677	DNA binding

0.59	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q14929|ZN169_HUMAN
Zinc finger protein 169
Search

0.64	Zinc finger protein 169

0.51	GO:1903506	regulation of nucleic acid-templated transcription
0.51	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.50	GO:0010468	regulation of gene expression
0.37	GO:0034968	histone lysine methylation
0.36	GO:0006351	transcription, DNA-templated

0.51	GO:0003676	nucleic acid binding
0.47	GO:0046872	metal ion binding
0.37	GO:0018024	histone-lysine N-methyltransferase activity
0.35	GO:0005515	protein binding
0.35	GO:0003700	DNA binding transcription factor activity

0.42	GO:0005622	intracellular
0.35	GO:0043227	membrane-bounded organelle

0.37

GO:0018024

sp|Q14934|NFAC4_HUMAN
Nuclear factor of activated T-cells, cytoplasmic 4
Search

NFATC4

0.96	Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4

0.66	GO:1902894	negative regulation of pri-miRNA transcription by RNA polymerase II
0.63	GO:2000297	negative regulation of synapse maturation
0.62	GO:0071285	cellular response to lithium ion
0.62	GO:0035562	negative regulation of chromatin binding
0.62	GO:0033173	calcineurin-NFAT signaling cascade
0.62	GO:0050774	negative regulation of dendrite morphogenesis
0.61	GO:0051145	smooth muscle cell differentiation
0.61	GO:0001569	branching involved in blood vessel morphogenesis
0.59	GO:0032760	positive regulation of tumor necrosis factor production
0.59	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage

0.61	GO:0003700	DNA binding transcription factor activity
0.60	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.53	GO:0008134	transcription factor binding
0.44	GO:0042975	peroxisome proliferator activated receptor binding
0.36	GO:0003713	transcription coactivator activity
0.35	GO:0003682	chromatin binding
0.32	GO:0017150	tRNA dihydrouridine synthase activity
0.31	GO:0050660	flavin adenine dinucleotide binding
0.31	GO:0003723	RNA binding

0.56	GO:0016607	nuclear speck
0.53	GO:0005667	transcription factor complex
0.53	GO:0005829	cytosol

sp|Q14938|NFIX_HUMAN
Nuclear factor 1 X-type
Search

NFIX

0.78	Nuclear factor 1 X-type

0.66	GO:0006260	DNA replication
0.57	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.51	GO:0051254	positive regulation of RNA metabolic process
0.50	GO:0010557	positive regulation of macromolecule biosynthetic process
0.50	GO:0031328	positive regulation of cellular biosynthetic process
0.50	GO:0051253	negative regulation of RNA metabolic process
0.50	GO:0010558	negative regulation of macromolecule biosynthetic process

0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0003677	DNA binding
0.38	GO:0001067	regulatory region nucleic acid binding
0.35	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part

sp|Q14940|SL9A5_HUMAN
Sodium/hydrogen exchanger 5
Search

SLC9A5

0.60	Sodium/hydrogen exchanger

0.79	GO:0006885	regulation of pH
0.77	GO:0035725	sodium ion transmembrane transport
0.63	GO:1902600	hydrogen ion transmembrane transport
0.53	GO:0099587	inorganic ion import across plasma membrane
0.48	GO:0030004	cellular monovalent inorganic cation homeostasis
0.45	GO:0071805	potassium ion transmembrane transport
0.34	GO:0035023	regulation of Rho protein signal transduction
0.34	GO:0051384	response to glucocorticoid
0.34	GO:0002028	regulation of sodium ion transport
0.34	GO:0007623	circadian rhythm

0.81	GO:0015385	sodium:proton antiporter activity
0.49	GO:0015386	potassium:proton antiporter activity
0.45	GO:0030165	PDZ domain binding
0.34	GO:0005089	Rho guanyl-nucleotide exchange factor activity

0.46	GO:0031526	brush border membrane
0.44	GO:0016324	apical plasma membrane
0.43	GO:0070062	extracellular exosome
0.34	GO:0009986	cell surface
0.30	GO:0016021	integral component of membrane

sp|Q14943|KI3S1_HUMAN
Killer cell immunoglobulin-like receptor 3DS1
Search

KIR3DL1

0.95	Natural killer cell inhibitory receptor

0.37	GO:0045087	innate immune response
0.36	GO:0050776	regulation of immune response
0.35	GO:0001909	leukocyte mediated cytotoxicity
0.35	GO:0030101	natural killer cell activation
0.35	GO:0006968	cellular defense response
0.35	GO:0002449	lymphocyte mediated immunity
0.34	GO:0007165	signal transduction

0.38	GO:0032393	MHC class I receptor activity
0.35	GO:0001540	amyloid-beta binding
0.35	GO:0005515	protein binding

0.35

GO:0005887

integral component of plasma membrane

sp|Q14952|KI2S3_HUMAN
Killer cell immunoglobulin-like receptor 2DS3
Search

0.93	Natural killer cell inhibitory receptor

0.40	GO:0006955	immune response
0.38	GO:0006952	defense response
0.38	GO:0050776	regulation of immune response
0.36	GO:0007165	signal transduction
0.34	GO:0030101	natural killer cell activation

0.38	GO:0032393	MHC class I receptor activity
0.36	GO:0005515	protein binding
0.35	GO:0003823	antigen binding

0.38

GO:0005887

integral component of plasma membrane

sp|Q14953|KI2S5_HUMAN
Killer cell immunoglobulin-like receptor 2DS5
Search

0.93	Natural killer cell inhibitory receptor

0.40	GO:0006955	immune response
0.39	GO:0006952	defense response
0.38	GO:0050776	regulation of immune response
0.37	GO:0007165	signal transduction
0.36	GO:0030101	natural killer cell activation

0.40	GO:0032393	MHC class I receptor activity
0.37	GO:0005515	protein binding
0.35	GO:0003823	antigen binding

0.39

GO:0005887

integral component of plasma membrane

sp|Q14954|KI2S1_HUMAN
Killer cell immunoglobulin-like receptor 2DS1
Search

0.93	Natural killer cell inhibitory receptor

0.40	GO:0006955	immune response
0.38	GO:0006952	defense response
0.38	GO:0050776	regulation of immune response
0.37	GO:0007165	signal transduction
0.34	GO:0030101	natural killer cell activation

0.39	GO:0032393	MHC class I receptor activity
0.36	GO:0005515	protein binding
0.35	GO:0003823	antigen binding

0.38

GO:0005887

integral component of plasma membrane

sp|Q14956|GPNMB_HUMAN
Transmembrane glycoprotein NMB
Search

GPNMB

0.97	Transmembrane glycoprotein NMB

0.67	GO:0031954	positive regulation of protein autophosphorylation
0.66	GO:0042130	negative regulation of T cell proliferation
0.66	GO:0034103	regulation of tissue remodeling
0.65	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle
0.64	GO:1901215	negative regulation of neuron death
0.63	GO:0001818	negative regulation of cytokine production
0.62	GO:0030335	positive regulation of cell migration
0.59	GO:0010469	regulation of receptor activity
0.58	GO:0007267	cell-cell signaling
0.52	GO:0032680	regulation of tumor necrosis factor production

0.69	GO:0045545	syndecan binding
0.63	GO:0008201	heparin binding
0.59	GO:0048018	receptor ligand activity
0.56	GO:0005178	integrin binding

0.48	GO:0005887	integral component of plasma membrane
0.47	GO:0031410	cytoplasmic vesicle
0.35	GO:0012506	vesicle membrane
0.34	GO:0012505	endomembrane system
0.33	GO:0044446	intracellular organelle part

sp|Q14957|NMDE3_HUMAN
Glutamate receptor ionotropic, NMDA 2C
Search

GRIN2C

0.92	N-methyl-D-aspartate receptor subunit

0.78	GO:0060079	excitatory postsynaptic potential
0.76	GO:0035235	ionotropic glutamate receptor signaling pathway
0.61	GO:0097553	calcium ion transmembrane import into cytosol
0.61	GO:0019722	calcium-mediated signaling
0.61	GO:0050905	neuromuscular process
0.61	GO:0033058	directional locomotion
0.56	GO:0042177	negative regulation of protein catabolic process
0.54	GO:0009611	response to wounding
0.48	GO:0051930	regulation of sensory perception of pain
0.47	GO:0008104	protein localization

0.80	GO:0005234	extracellularly glutamate-gated ion channel activity
0.77	GO:0004970	ionotropic glutamate receptor activity
0.62	GO:0099604	ligand-gated calcium channel activity
0.57	GO:0022843	voltage-gated cation channel activity
0.38	GO:0005515	protein binding
0.36	GO:0098772	molecular function regulator
0.36	GO:0016595	glutamate binding
0.35	GO:0042165	neurotransmitter binding

0.77	GO:0098794	postsynapse
0.76	GO:0097060	synaptic membrane
0.71	GO:0030054	cell junction
0.65	GO:0017146	NMDA selective glutamate receptor complex
0.56	GO:0032279	asymmetric synapse
0.52	GO:0097458	neuron part
0.41	GO:0043226	organelle
0.39	GO:0005622	intracellular

sp|Q14964|RB39A_HUMAN
Ras-related protein Rab-39A
Search

0.96	RAB39, member RAS oncogene family (Predicted)

0.57	GO:0090383	phagosome acidification
0.57	GO:0090385	phagosome-lysosome fusion
0.47	GO:0010506	regulation of autophagy
0.46	GO:0050808	synapse organization
0.38	GO:0006914	autophagy
0.36	GO:0015031	protein transport
0.33	GO:0006511	ubiquitin-dependent protein catabolic process

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0031489	myosin V binding
0.33	GO:0031625	ubiquitin protein ligase binding

0.54	GO:0031982	vesicle
0.51	GO:0005794	Golgi apparatus
0.48	GO:0043005	neuron projection
0.36	GO:0005764	lysosome
0.36	GO:0031090	organelle membrane
0.35	GO:0098805	whole membrane
0.35	GO:0044446	intracellular organelle part
0.35	GO:0005886	plasma membrane
0.34	GO:0005829	cytosol
0.33	GO:0031461	cullin-RING ubiquitin ligase complex

sp|Q14966|ZN638_HUMAN
Zinc finger protein 638
Search

ZNF638

0.82	Zinc finger protein 638

0.74	GO:0008380	RNA splicing
0.35	GO:0006334	nucleosome assembly
0.32	GO:0006351	transcription, DNA-templated
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.58	GO:0003723	RNA binding
0.55	GO:0008270	zinc ion binding
0.33	GO:0003677	DNA binding

0.54	GO:0005634	nucleus
0.45	GO:0031974	membrane-enclosed lumen
0.41	GO:0044446	intracellular organelle part
0.34	GO:0044815	DNA packaging complex
0.34	GO:0032993	protein-DNA complex
0.34	GO:0005694	chromosome
0.31	GO:0005737	cytoplasm

sp|Q14973|NTCP_HUMAN
Sodium/bile acid cotransporter
Search

SLC10A1

0.97	Solute carrier family 10 sodium/bile acid cotransporter member 1

0.82

GO:0015721

bile acid and bile salt transport

0.84

GO:0008508

bile acid:sodium symporter activity

0.34	GO:0016324	apical plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q14974|IMB1_HUMAN
Importin subunit beta-1
Search

KPNB1

0.85	Karyopherin subunit beta 1

0.71	GO:0007079	mitotic chromosome movement towards spindle pole
0.71	GO:0006610	ribosomal protein import into nucleus
0.70	GO:0031291	Ran protein signal transduction
0.70	GO:0030953	astral microtubule organization
0.69	GO:0006886	intracellular protein transport
0.66	GO:0007080	mitotic metaphase plate congression
0.66	GO:0090307	mitotic spindle assembly
0.66	GO:0040001	establishment of mitotic spindle localization
0.53	GO:0006607	NLS-bearing protein import into nucleus

0.80	GO:0008536	Ran GTPase binding
0.66	GO:0051879	Hsp90 protein binding
0.61	GO:0019904	protein domain specific binding
0.57	GO:0008565	protein transporter activity
0.53	GO:0008139	nuclear localization sequence binding

0.67	GO:0071782	endoplasmic reticulum tubular network
0.64	GO:0031965	nuclear membrane
0.56	GO:0005654	nucleoplasm
0.55	GO:0005829	cytosol
0.51	GO:0034399	nuclear periphery
0.49	GO:0043234	protein complex

sp|Q14978|NOLC1_HUMAN
Nucleolar and coiled-body phosphoprotein 1
Search

NOLC1

0.84	Nucleolar and coiled-body phosphoprotein 1

0.85	GO:0014029	neural crest formation
0.84	GO:0007000	nucleolus organization
0.81	GO:0014032	neural crest cell development
0.69	GO:0006417	regulation of translation
0.41	GO:0048701	embryonic cranial skeleton morphogenesis
0.35	GO:0033979	box H/ACA snoRNA metabolic process
0.34	GO:0042306	regulation of protein import into nucleus
0.34	GO:0006970	response to osmotic stress
0.34	GO:0008284	positive regulation of cell proliferation
0.34	GO:0045893	positive regulation of transcription, DNA-templated

0.85	GO:0001042	RNA polymerase I core binding
0.71	GO:0046982	protein heterodimerization activity
0.39	GO:0016758	transferase activity, transferring hexosyl groups
0.35	GO:0034512	box C/D snoRNA binding
0.35	GO:0034513	box H/ACA snoRNA binding
0.35	GO:0046872	metal ion binding
0.35	GO:0008139	nuclear localization sequence binding
0.34	GO:0019904	protein domain specific binding
0.34	GO:0008134	transcription factor binding
0.33	GO:0032550	purine ribonucleoside binding

0.82	GO:0015030	Cajal body
0.79	GO:0001650	fibrillar center
0.43	GO:0030532	small nuclear ribonucleoprotein complex
0.35	GO:0005737	cytoplasm
0.35	GO:0031428	box C/D snoRNP complex
0.34	GO:0031429	box H/ACA snoRNP complex
0.30	GO:0031224	intrinsic component of membrane

0.39

GO:0016758

sp|Q14980|NUMA1_HUMAN
Nuclear mitotic apparatus protein 1
Search

NUMA1

0.95	Nuclear mitotic apparatus protein 1

0.61	GO:1902365	positive regulation of protein localization to spindle pole body
0.61	GO:0055048	anastral spindle assembly
0.60	GO:0110028	positive regulation of mitotic spindle organization
0.59	GO:1905832	positive regulation of spindle assembly
0.59	GO:0045618	positive regulation of keratinocyte differentiation
0.59	GO:0051798	positive regulation of hair follicle development
0.59	GO:1904778	positive regulation of protein localization to cell cortex
0.58	GO:0030953	astral microtubule organization
0.58	GO:0090235	regulation of metaphase plate congression
0.58	GO:0032888	regulation of mitotic spindle elongation

0.58	GO:0051011	microtubule minus-end binding
0.57	GO:0097718	disordered domain specific binding
0.56	GO:0051010	microtubule plus-end binding
0.55	GO:0070840	dynein complex binding
0.55	GO:0008022	protein C-terminus binding
0.52	GO:0035091	phosphatidylinositol binding
0.35	GO:0003684	damaged DNA binding
0.34	GO:0005198	structural molecule activity
0.32	GO:0005262	calcium channel activity

0.74	GO:0000139	Golgi membrane
0.61	GO:1905720	cytoplasmic microtubule bundle
0.59	GO:0097575	lateral cell cortex
0.59	GO:0061673	mitotic spindle astral microtubule
0.58	GO:0036449	microtubule minus-end
0.58	GO:0055028	cortical microtubule
0.58	GO:0097431	mitotic spindle pole
0.58	GO:0031616	spindle pole centrosome
0.57	GO:0035371	microtubule plus-end
0.56	GO:0016363	nuclear matrix

sp|Q14982|OPCM_HUMAN
Opioid-binding protein/cell adhesion molecule
Search

OPCML

0.87	Opioid binding protein/cell adhesion molecule like

0.63	GO:0007155	cell adhesion
0.52	GO:0006501	C-terminal protein lipidation
0.50	GO:0008038	neuron recognition
0.44	GO:0032355	response to estradiol
0.44	GO:0021549	cerebellum development
0.44	GO:0010977	negative regulation of neuron projection development

0.42

GO:0005515

protein binding

0.69	GO:0031225	anchored component of membrane
0.50	GO:0005886	plasma membrane
0.50	GO:0070062	extracellular exosome
0.44	GO:0060076	excitatory synapse
0.42	GO:0030424	axon
0.42	GO:0048471	perinuclear region of cytoplasm
0.41	GO:0009986	cell surface
0.30	GO:0016021	integral component of membrane

sp|Q14990|ODFP1_HUMAN
Outer dense fiber protein 1
Search

ODF1

0.96	LOW QUALITY PROTEIN: outer dense fiber protein 1

0.47	GO:0007283	spermatogenesis
0.44	GO:0030154	cell differentiation
0.44	GO:0007275	multicellular organism development

0.40

GO:0019904

protein domain specific binding

0.87	GO:0001520	outer dense fiber
0.37	GO:0005634	nucleus

sp|Q14993|COJA1_HUMAN
Collagen alpha-1(XIX) chain
Search

COL19A1

0.93	Collagen type XIX alpha 1 chain

0.51	GO:0007519	skeletal muscle tissue development
0.50	GO:0030198	extracellular matrix organization
0.43	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.42	GO:0007155	cell adhesion
0.42	GO:0033622	integrin activation
0.41	GO:0035987	endodermal cell differentiation
0.41	GO:0051894	positive regulation of focal adhesion assembly
0.41	GO:0071495	cellular response to endogenous stimulus
0.41	GO:0071310	cellular response to organic substance
0.40	GO:0043200	response to amino acid

0.57	GO:0005201	extracellular matrix structural constituent
0.40	GO:0005178	integrin binding
0.39	GO:0004867	serine-type endopeptidase inhibitor activity
0.36	GO:0042802	identical protein binding
0.35	GO:0004838	L-tyrosine:2-oxoglutarate aminotransferase activity
0.34	GO:0042302	structural constituent of cuticle
0.34	GO:0030674	protein binding, bridging
0.34	GO:0046983	protein dimerization activity
0.34	GO:0004872	receptor activity
0.33	GO:0030246	carbohydrate binding

0.68	GO:0005581	collagen trimer
0.57	GO:0005604	basement membrane
0.43	GO:0098645	collagen network
0.38	GO:0031594	neuromuscular junction
0.38	GO:0030056	hemidesmosome
0.37	GO:0005615	extracellular space
0.37	GO:0005788	endoplasmic reticulum lumen
0.34	GO:1903561	extracellular vesicle
0.33	GO:0005634	nucleus
0.33	GO:0005911	cell-cell junction

0.35

EC:2.6.1.5

GO:0004838

sp|Q14994|NR1I3_HUMAN
Nuclear receptor subfamily 1 group I member 3
Search

NR1I3

0.94	Nuclear receptor subfamily 1 group I member 3

0.78	GO:0043401	steroid hormone mediated signaling pathway
0.66	GO:0030522	intracellular receptor signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:0045944	positive regulation of transcription by RNA polymerase II
0.56	GO:0045892	negative regulation of transcription, DNA-templated
0.44	GO:0042738	exogenous drug catabolic process
0.42	GO:0046618	drug export
0.41	GO:0042908	xenobiotic transport
0.41	GO:0006805	xenobiotic metabolic process
0.37	GO:0001649	osteoblast differentiation

0.80	GO:0003707	steroid hormone receptor activity
0.69	GO:0004887	thyroid hormone receptor activity
0.63	GO:0043565	sequence-specific DNA binding
0.61	GO:0008270	zinc ion binding
0.61	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.59	GO:0001012	RNA polymerase II regulatory region DNA binding
0.56	GO:0003690	double-stranded DNA binding
0.37	GO:0003713	transcription coactivator activity
0.35	GO:0008144	drug binding
0.35	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.54	GO:0031974	membrane-enclosed lumen
0.52	GO:0005829	cytosol
0.47	GO:0044446	intracellular organelle part
0.46	GO:0005856	cytoskeleton

sp|Q14995|NR1D2_HUMAN
Nuclear receptor subfamily 1 group D member 2
Search

NR1D2

0.97	Nuclear receptor Rev-ErbA beta variant 1

0.77	GO:0043401	steroid hormone mediated signaling pathway
0.58	GO:2000505	regulation of energy homeostasis
0.57	GO:2001014	regulation of skeletal muscle cell differentiation
0.57	GO:0006351	transcription, DNA-templated
0.57	GO:0042752	regulation of circadian rhythm
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0019216	regulation of lipid metabolic process
0.54	GO:0055088	lipid homeostasis

0.78	GO:0003707	steroid hormone receptor activity
0.64	GO:0043565	sequence-specific DNA binding
0.62	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.58	GO:0001047	core promoter binding
0.56	GO:0035326	enhancer binding
0.54	GO:0001012	RNA polymerase II regulatory region DNA binding
0.52	GO:0003690	double-stranded DNA binding
0.41	GO:0001222	transcription corepressor binding
0.36	GO:0020037	heme binding

0.61	GO:0005634	nucleus
0.49	GO:0070013	intracellular organelle lumen
0.45	GO:0044446	intracellular organelle part
0.40	GO:0043197	dendritic spine
0.38	GO:0005694	chromosome
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q14997|PSME4_HUMAN
Proteasome activator complex subunit 4
Search

PSME4

0.89	Proteasome activator complex subunit 4

0.80	GO:0010952	positive regulation of peptidase activity
0.62	GO:0035093	spermatogenesis, exchange of chromosomal proteins
0.59	GO:0010499	proteasomal ubiquitin-independent protein catabolic process
0.47	GO:0006281	DNA repair
0.37	GO:0007275	multicellular organism development
0.36	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.36	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.36	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.36	GO:0038095	Fc-epsilon receptor signaling pathway
0.36	GO:1902036	regulation of hematopoietic stem cell differentiation

0.82	GO:0070577	lysine-acetylated histone binding
0.82	GO:0016504	peptidase activator activity
0.81	GO:0070628	proteasome binding

0.65	GO:1905369	endopeptidase complex
0.54	GO:0043234	protein complex
0.50	GO:0005829	cytosol
0.49	GO:0005654	nucleoplasm
0.30	GO:0044425	membrane part

sp|Q14999|CUL7_HUMAN
Cullin-7
Search

CUL7

0.93	Cullin-7 isoform 2

0.74	GO:0000226	microtubule cytoskeleton organization
0.72	GO:0006511	ubiquitin-dependent protein catabolic process
0.71	GO:0016567	protein ubiquitination
0.59	GO:0050775	positive regulation of dendrite morphogenesis
0.58	GO:0007088	regulation of mitotic nuclear division
0.58	GO:0001837	epithelial to mesenchymal transition
0.58	GO:0001570	vasculogenesis
0.57	GO:0001890	placenta development
0.56	GO:0000281	mitotic cytokinesis
0.39	GO:0007030	Golgi organization

0.78	GO:0031625	ubiquitin protein ligase binding
0.39	GO:0046872	metal ion binding
0.35	GO:0003735	structural constituent of ribosome
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.85	GO:1990393	3M complex
0.85	GO:0031467	Cul7-RING ubiquitin ligase complex
0.55	GO:0048471	perinuclear region of cytoplasm
0.54	GO:0005813	centrosome
0.51	GO:0005794	Golgi apparatus
0.38	GO:0005829	cytosol
0.37	GO:0005680	anaphase-promoting complex
0.34	GO:0005840	ribosome

sp|Q149M9|NWD1_HUMAN
NACHT domain- and WD repeat-containing protein 1
Search

NWD1

0.88	LOW QUALITY PROTEIN: NACHT domain- and WD repeat-containing protein 1

0.70	GO:0008380	RNA splicing
0.40	GO:2001141	regulation of RNA biosynthetic process
0.40	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.40	GO:0010468	regulation of gene expression

0.57	GO:0003723	RNA binding
0.41	GO:0032559	adenyl ribonucleotide binding
0.41	GO:0008144	drug binding
0.41	GO:0035639	purine ribonucleoside triphosphate binding
0.30	GO:0003824	catalytic activity

0.81	GO:0071011	precatalytic spliceosome
0.80	GO:0005682	U5 snRNP
0.77	GO:0071013	catalytic step 2 spliceosome
0.47	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q149N8|SHPRH_HUMAN
E3 ubiquitin-protein ligase SHPRH
Search

SHPRH

0.95	SNF2 histone linker PHD RING helicase

0.78	GO:0006334	nucleosome assembly
0.67	GO:0000209	protein polyubiquitination
0.55	GO:0006974	cellular response to DNA damage stimulus

0.65	GO:0031625	ubiquitin protein ligase binding
0.61	GO:0004842	ubiquitin-protein transferase activity
0.54	GO:0030554	adenyl nucleotide binding
0.54	GO:0003677	DNA binding
0.54	GO:0046872	metal ion binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0004386	helicase activity
0.45	GO:0016874	ligase activity

0.73	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.45	EC:6	GO:0016874
0.61	KEGG:R03876	GO:0004842

sp|Q14BN4|SLMAP_HUMAN
Sarcolemmal membrane-associated protein
Search

SLMAP

0.91	Sarcolemma associated protein

0.83	GO:0006936	muscle contraction
0.70	GO:1905150	regulation of voltage-gated sodium channel activity
0.69	GO:1900825	regulation of membrane depolarization during cardiac muscle cell action potential
0.63	GO:0072659	protein localization to plasma membrane

0.52	GO:0005615	extracellular space
0.30	GO:0016020	membrane

sp|Q14C86|GAPD1_HUMAN
GTPase-activating protein and VPS9 domain-containing protein 1
Search

GAPVD1

0.93	GTPase-activating protein and VPS9 domain-containing protein 1

0.74	GO:0043087	regulation of GTPase activity
0.60	GO:0007165	signal transduction
0.54	GO:0051223	regulation of protein transport
0.38	GO:0051345	positive regulation of hydrolase activity
0.37	GO:0006897	endocytosis
0.34	GO:0061024	membrane organization

0.60	GO:0032794	GTPase activating protein binding
0.54	GO:0045296	cadherin binding
0.53	GO:0005085	guanyl-nucleotide exchange factor activity
0.38	GO:0005096	GTPase activator activity
0.36	GO:0017137	Rab GTPase binding

0.51	GO:0005829	cytosol
0.38	GO:0005768	endosome
0.30	GO:0016021	integral component of membrane

sp|Q14C87|T132D_HUMAN
Transmembrane protein 132D
Search

TMEM132D

0.92	Transmembrane protein 132D

0.52

GO:0010923

negative regulation of phosphatase activity

0.34

GO:0005515

protein binding

0.30

GO:0044425

membrane part

sp|Q14CB8|RHG19_HUMAN
Rho GTPase-activating protein 19
Search

ARHGAP19

0.95	Rho GTPase-activating protein 19

0.60	GO:0007165	signal transduction
0.40	GO:0043547	positive regulation of GTPase activity
0.36	GO:0051056	regulation of small GTPase mediated signal transduction

0.40

GO:0005096

GTPase activator activity

0.35	GO:0005829	cytosol
0.35	GO:0043227	membrane-bounded organelle
0.35	GO:0005886	plasma membrane
0.34	GO:0043229	intracellular organelle

sp|Q14CM0|FRPD4_HUMAN
FERM and PDZ domain-containing protein 4
Search

FRMPD4

0.97	FERM and PDZ domain-containing protein 4

0.61	GO:0051835	positive regulation of synapse structural plasticity
0.34	GO:0007165	signal transduction

0.57	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.34	GO:0005515	protein binding

0.67	GO:0005856	cytoskeleton
0.57	GO:0043197	dendritic spine
0.43	GO:0043234	protein complex

sp|Q14CN2|CLCA4_HUMAN
Calcium-activated chloride channel regulator 4
Search

0.88	Calcium-activated chloride channel regulator 4

0.76	GO:1902476	chloride transmembrane transport
0.39	GO:0006816	calcium ion transport
0.37	GO:0071456	cellular response to hypoxia
0.37	GO:0006508	proteolysis
0.37	GO:0043276	anoikis
0.37	GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand

0.86	GO:0061778	intracellular chloride channel activity
0.72	GO:0022839	ion gated channel activity
0.71	GO:0008381	mechanosensitive ion channel activity
0.39	GO:0008237	metallopeptidase activity
0.38	GO:0022834	ligand-gated channel activity
0.36	GO:0046872	metal ion binding
0.35	GO:0004175	endopeptidase activity

0.51	GO:0005902	microvillus
0.49	GO:0030141	secretory granule
0.49	GO:0005887	integral component of plasma membrane
0.40	GO:0005615	extracellular space
0.38	GO:0016324	apical plasma membrane
0.38	GO:0031965	nuclear membrane
0.37	GO:0030054	cell junction
0.37	GO:1903561	extracellular vesicle
0.36	GO:0030659	cytoplasmic vesicle membrane
0.36	GO:0005829	cytosol

sp|Q14CN4|K2C72_HUMAN
Keratin, type II cytoskeletal 72
Search

0.96	LOW QUALITY PROTEIN: keratin, type II cytoskeletal 72

0.55	GO:0045104	intermediate filament cytoskeleton organization
0.51	GO:0031069	hair follicle morphogenesis
0.45	GO:0097435	supramolecular fiber organization
0.40	GO:0070268	cornification
0.35	GO:0050680	negative regulation of epithelial cell proliferation

0.62	GO:0005198	structural molecule activity
0.48	GO:1990254	keratin filament binding

0.83	GO:0045095	keratin filament
0.41	GO:0070062	extracellular exosome
0.37	GO:0005737	cytoplasm
0.35	GO:0009986	cell surface
0.34	GO:0005634	nucleus

sp|Q14CS0|UBX2B_HUMAN
UBX domain-containing protein 2B
Search

UBXN2B

0.97	UBX domain-containing protein 2B

0.77	GO:0031468	nuclear envelope reassembly
0.73	GO:0000045	autophagosome assembly
0.73	GO:0007030	Golgi organization
0.69	GO:0043666	regulation of phosphoprotein phosphatase activity
0.68	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.62	GO:0061025	membrane fusion

0.72	GO:0043130	ubiquitin binding
0.70	GO:0019888	protein phosphatase regulator activity
0.45	GO:0051117	ATPase binding
0.45	GO:0008289	lipid binding
0.36	GO:0043168	anion binding

0.69	GO:0005829	cytosol
0.64	GO:0045111	intermediate filament cytoskeleton
0.61	GO:0005634	nucleus
0.56	GO:0031974	membrane-enclosed lumen
0.51	GO:0005794	Golgi apparatus
0.49	GO:0044446	intracellular organelle part
0.48	GO:0005886	plasma membrane
0.47	GO:1990730	VCP-NSFL1C complex
0.45	GO:0005783	endoplasmic reticulum
0.41	GO:0005694	chromosome

sp|Q14CW9|AT7L3_HUMAN
Ataxin-7-like protein 3
Search

ATXN7L3

0.97	Ataxin-7-like protein 3

0.83	GO:0016578	histone deubiquitination
0.72	GO:0045893	positive regulation of transcription, DNA-templated
0.57	GO:0006351	transcription, DNA-templated
0.53	GO:0010390	histone monoubiquitination
0.34	GO:0098656	anion transmembrane transport
0.34	GO:0015698	inorganic anion transport

0.78	GO:0003713	transcription coactivator activity
0.62	GO:0008270	zinc ion binding
0.35	GO:0005452	inorganic anion exchanger activity
0.33	GO:0005515	protein binding
0.33	GO:0003677	DNA binding

0.85	GO:0071819	DUBm complex
0.79	GO:0000124	SAGA complex
0.30	GO:0016020	membrane

sp|Q14CX5|MF13A_HUMAN
Transmembrane protein 180
Search

MFSD13A

0.47	Putative na+/melibiose symporter and related transporter carbohydrate transport and metabolism

0.32

GO:0007165

signal transduction

0.30

GO:0044425

membrane part

sp|Q14CX7|NAA25_HUMAN
N-alpha-acetyltransferase 25, NatB auxiliary subunit
Search

NAA25

0.96	N-alpha-acetyltransferase 25, NatB auxiliary subunit

0.52	GO:0017196	N-terminal peptidyl-methionine acetylation
0.33	GO:0009306	protein secretion

0.49

GO:0004596

peptide alpha-N-acetyltransferase activity

0.52	GO:0005794	Golgi apparatus
0.52	GO:0031416	NatB complex
0.51	GO:0005829	cytosol
0.33	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0031224	intrinsic component of membrane

0.49

EC:2.3.1.88

GO:0004596

sp|Q14CZ0|CP072_HUMAN
UPF0472 protein C16orf72
Search

0.47	GO:0071466	cellular response to xenobiotic stimulus
0.40	GO:0043043	peptide biosynthetic process
0.39	GO:0044267	cellular protein metabolic process
0.38	GO:0010467	gene expression
0.38	GO:0009059	macromolecule biosynthetic process
0.37	GO:0016310	phosphorylation

0.43	GO:0005515	protein binding
0.41	GO:0003735	structural constituent of ribosome
0.37	GO:0016301	kinase activity

0.41	GO:0005840	ribosome
0.30	GO:0044425	membrane part

sp|Q14CZ7|FAKD3_HUMAN
FAST kinase domain-containing protein 3, mitochondrial
Search

FASTKD3

0.97	FAST kinase domain-containing protein 3

0.63	GO:0006468	protein phosphorylation
0.61	GO:0044528	regulation of mitochondrial mRNA stability
0.59	GO:0070131	positive regulation of mitochondrial translation
0.57	GO:0033617	mitochondrial respiratory chain complex IV assembly
0.46	GO:0045333	cellular respiration

0.64	GO:0004672	protein kinase activity
0.35	GO:0003723	RNA binding
0.34	GO:0005515	protein binding

0.46	GO:0005634	nucleus
0.46	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

sp|Q14CZ8|HECAM_HUMAN
Hepatocyte cell adhesion molecule
Search

HEPACAM

0.97	Hepatic and glial cell adhesion molecule a

0.51	GO:0034613	cellular protein localization
0.40	GO:0007050	cell cycle arrest
0.39	GO:0040008	regulation of growth
0.38	GO:0007155	cell adhesion

0.34

GO:0005515

protein binding

0.58	GO:0030424	axon
0.58	GO:0005911	cell-cell junction
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q14D04|MELT_HUMAN
Ventricular zone-expressed PH domain-containing protein homolog 1
Search

VEPH1

0.97	Ventricular zone-expressed PH domain-containing protein like protein 1

0.47	GO:0042471	ear morphogenesis
0.46	GO:0007420	brain development

0.56

GO:0005886

plasma membrane

sp|Q14D33|RTP5_HUMAN
Receptor-transporting protein 5
Search

RTP5

0.96	Receptor-transporting protein 5

0.68	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste
0.60	GO:0051205	protein insertion into membrane
0.60	GO:0006612	protein targeting to membrane

0.72

GO:0031849

olfactory receptor binding

0.60	GO:0009986	cell surface
0.40	GO:0005622	intracellular
0.30	GO:0016020	membrane

sp|Q14DG7|T132B_HUMAN
Transmembrane protein 132B
Search

TMEM132B

0.89	Transmembrane protein 132B

0.34	GO:0010923	negative regulation of phosphatase activity
0.34	GO:0006629	lipid metabolic process

0.35

GO:0030729

acetoacetate-CoA ligase activity

0.30

GO:0031224

intrinsic component of membrane

0.35	EC:6.2.1.16	GO:0030729
0.35	KEGG:R01357	GO:0030729

sp|Q15003|CND2_HUMAN
Condensin complex subunit 2
Search

NCAPH

0.75	Non-SMC condensin I complex subunit H

0.81	GO:0007076	mitotic chromosome condensation
0.62	GO:0051301	cell division
0.55	GO:2000373	positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity
0.49	GO:0010032	meiotic chromosome condensation
0.47	GO:0045132	meiotic chromosome segregation
0.36	GO:0007143	female meiotic nuclear division
0.35	GO:0051304	chromosome separation
0.34	GO:0016192	vesicle-mediated transport

0.55	GO:0072587	DNA topoisomerase (ATP-hydrolyzing) activator activity
0.55	GO:0044547	DNA topoisomerase binding
0.48	GO:0003682	chromatin binding

0.82	GO:0000796	condensin complex
0.51	GO:0005829	cytosol
0.49	GO:0000794	condensed nuclear chromosome
0.47	GO:0044454	nuclear chromosome part
0.30	GO:0031224	intrinsic component of membrane

sp|Q15004|PAF15_HUMAN
PCNA-associated factor
Search

0.97	PCNA-associated factor

0.73	GO:0051726	regulation of cell cycle
0.65	GO:0006974	cellular response to DNA damage stimulus
0.52	GO:0007098	centrosome cycle
0.51	GO:0009411	response to UV
0.46	GO:0071897	DNA biosynthetic process
0.45	GO:0006260	DNA replication

0.50	GO:0003682	chromatin binding
0.37	GO:0005515	protein binding

0.50	GO:0048471	perinuclear region of cytoplasm
0.45	GO:0005813	centrosome
0.43	GO:0005634	nucleus
0.37	GO:0031974	membrane-enclosed lumen

sp|Q15005|SPCS2_HUMAN
Signal peptidase complex subunit 2
Search

SPCS2

0.92	Signal peptidase complex subunit 2

0.80	GO:0006465	signal peptide processing
0.45	GO:0045047	protein targeting to ER
0.35	GO:0032367	intracellular cholesterol transport
0.34	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.33	GO:0007186	G-protein coupled receptor signaling pathway

0.61	GO:0008233	peptidase activity
0.35	GO:0017127	cholesterol transporter activity
0.34	GO:0004308	exo-alpha-sialidase activity
0.34	GO:0004984	olfactory receptor activity
0.33	GO:0004930	G-protein coupled receptor activity
0.33	GO:0016887	ATPase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.82	GO:0005787	signal peptidase complex
0.37	GO:0031090	organelle membrane
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.61

GO:0008233

sp|Q15006|EMC2_HUMAN
ER membrane protein complex subunit 2
Search

EMC2

0.93	ER membrane protein complex subunit 2

0.66

GO:0034975

protein folding in endoplasmic reticulum

0.36

GO:0005515

protein binding

0.83	GO:0072546	ER membrane protein complex
0.57	GO:0005739	mitochondrion
0.46	GO:0005634	nucleus

sp|Q15007|FL2D_HUMAN
Pre-mRNA-splicing regulator WTAP
Search

WTAP

0.95	Pre-mRNA-splicing regulator WTAP

0.84	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.80	GO:0080009	mRNA methylation
0.40	GO:0042981	regulation of apoptotic process
0.38	GO:0008380	RNA splicing
0.37	GO:0006397	mRNA processing
0.37	GO:0007049	cell cycle
0.34	GO:0007275	multicellular organism development
0.33	GO:0000226	microtubule cytoskeleton organization

0.35	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
0.34	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.57	GO:0036396	RNA N6-methyladenosine methyltransferase complex
0.47	GO:0031974	membrane-enclosed lumen
0.46	GO:0012505	endomembrane system
0.44	GO:0031967	organelle envelope
0.44	GO:0031090	organelle membrane
0.33	GO:0015630	microtubule cytoskeleton
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:2.3.1

GO:0016747

sp|Q15008|PSMD6_HUMAN
26S proteasome non-ATPase regulatory subunit 6
Search

PSMD6

0.91	26S proteasome non-ATPase regulatory subunit 6

0.66	GO:0050790	regulation of catalytic activity
0.50	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.47	GO:0070306	lens fiber cell differentiation
0.36	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation
0.35	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia
0.35	GO:0043312	neutrophil degranulation
0.35	GO:2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process

0.68	GO:0030234	enzyme regulator activity
0.33	GO:0005515	protein binding
0.33	GO:0016887	ATPase activity

0.68	GO:1905369	endopeptidase complex
0.56	GO:0043234	protein complex
0.43	GO:0005622	intracellular
0.36	GO:0070062	extracellular exosome
0.35	GO:0031983	vesicle lumen
0.33	GO:0012505	endomembrane system

0.33

GO:0016887

sp|Q15011|HERP1_HUMAN
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein
Search

HERPUD1

0.92	Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein-like

0.59	GO:1903071	positive regulation of ER-associated ubiquitin-dependent protein catabolic process
0.58	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
0.57	GO:1903513	endoplasmic reticulum to cytosol transport
0.57	GO:0032469	endoplasmic reticulum calcium ion homeostasis
0.57	GO:0032527	protein exit from endoplasmic reticulum
0.56	GO:0032092	positive regulation of protein binding
0.55	GO:0030968	endoplasmic reticulum unfolded protein response
0.54	GO:0036503	ERAD pathway
0.54	GO:0031396	regulation of protein ubiquitination
0.50	GO:0006511	ubiquitin-dependent protein catabolic process

0.56

GO:0044325

ion channel binding

0.59	GO:1990037	Lewy body core
0.54	GO:0034704	calcium channel complex
0.50	GO:0005789	endoplasmic reticulum membrane

sp|Q15012|LAP4A_HUMAN
Lysosomal-associated transmembrane protein 4A
Search

LAPTM4A

0.96	Lysosomal-associated protein transmembrane 4 alpha

0.35	GO:1905671	regulation of lysosome organization
0.35	GO:1905166	negative regulation of lysosomal protein catabolic process
0.35	GO:0097213	regulation of lysosomal membrane permeability
0.35	GO:0032911	negative regulation of transforming growth factor beta1 production
0.35	GO:0007032	endosome organization
0.34	GO:0032509	endosome transport via multivesicular body sorting pathway

0.35	GO:0097001	ceramide binding
0.35	GO:1902936	phosphatidylinositol bisphosphate binding
0.34	GO:0005515	protein binding
0.33	GO:0005509	calcium ion binding

0.56	GO:0031902	late endosome membrane
0.55	GO:0005765	lysosomal membrane
0.50	GO:0005794	Golgi apparatus
0.35	GO:0097487	multivesicular body, internal vesicle
0.34	GO:0005769	early endosome
0.33	GO:0042995	cell projection
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q15013|MD2BP_HUMAN
MAD2L1-binding protein
Search

MAD2L1BP

0.97	MAD2L1-binding protein isoform 1

0.84	GO:0007096	regulation of exit from mitosis
0.58	GO:0007093	mitotic cell cycle checkpoint
0.36	GO:0071173	spindle assembly checkpoint
0.36	GO:0045841	negative regulation of mitotic metaphase/anaphase transition

0.35

GO:0005515

protein binding

0.61	GO:0005634	nucleus
0.51	GO:0012505	endomembrane system
0.51	GO:0031974	membrane-enclosed lumen
0.48	GO:0031967	organelle envelope
0.48	GO:0031090	organelle membrane
0.47	GO:0043232	intracellular non-membrane-bounded organelle
0.41	GO:0005737	cytoplasm

sp|Q15014|MO4L2_HUMAN
Mortality factor 4-like protein 2
Search

MORF4L2

0.88	Putative dosage compensation regulatory complex/histone acetyltransferase complex subunit

0.74	GO:0016569	covalent chromatin modification
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.48	GO:0006476	protein deacetylation
0.48	GO:0018393	internal peptidyl-lysine acetylation
0.46	GO:0006338	chromatin remodeling
0.44	GO:1902679	negative regulation of RNA biosynthetic process
0.42	GO:0040008	regulation of growth

0.43	GO:0047485	protein N-terminus binding
0.41	GO:0003682	chromatin binding
0.33	GO:0016740	transferase activity
0.32	GO:0003676	nucleic acid binding

0.80	GO:0035267	NuA4 histone acetyltransferase complex
0.72	GO:0016580	Sin3 complex
0.45	GO:0005730	nucleolus
0.42	GO:0016607	nuclear speck
0.39	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.33

GO:0016740

sp|Q15018|F175B_HUMAN
BRISC complex subunit Abro1
Search

ABRAXAS2

0.97	BRISC complex subunit Abraxas 2

0.85	GO:0002931	response to ischemia
0.85	GO:0070536	protein K63-linked deubiquitination
0.82	GO:0090307	mitotic spindle assembly
0.81	GO:0008608	attachment of spindle microtubules to kinetochore
0.46	GO:0071497	cellular response to freezing
0.42	GO:0051301	cell division
0.42	GO:0043066	negative regulation of apoptotic process

0.84	GO:0031593	polyubiquitin modification-dependent protein binding
0.72	GO:0008017	microtubule binding
0.34	GO:0003676	nucleic acid binding

0.85	GO:0036449	microtubule minus-end
0.85	GO:0031616	spindle pole centrosome
0.84	GO:0070552	BRISC complex
0.80	GO:0030496	midbody
0.48	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q15019|SEPT2_HUMAN
Septin-2
Search

SEPT2

0.92	Putative septins p-loop gtpase

0.67	GO:0051301	cell division
0.67	GO:0007049	cell cycle
0.57	GO:0002036	regulation of L-glutamate transport
0.54	GO:0007224	smoothened signaling pathway
0.53	GO:0060271	cilium assembly
0.49	GO:0032880	regulation of protein localization
0.47	GO:0050790	regulation of catalytic activity
0.39	GO:0007283	spermatogenesis
0.37	GO:0030154	cell differentiation
0.36	GO:0007399	nervous system development

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0045296	cadherin binding
0.52	GO:0032947	protein complex scaffold activity
0.48	GO:0030234	enzyme regulator activity
0.36	GO:0042802	identical protein binding
0.34	GO:0003924	GTPase activity

0.57	GO:0097227	sperm annulus
0.56	GO:0060170	ciliary membrane
0.55	GO:0031105	septin complex
0.55	GO:0032391	photoreceptor connecting cilium
0.53	GO:0043209	myelin sheath
0.53	GO:0005930	axoneme
0.51	GO:0009986	cell surface
0.50	GO:0045202	synapse
0.44	GO:0005634	nucleus
0.41	GO:0030496	midbody

sp|Q15020|SART3_HUMAN
Squamous cell carcinoma antigen recognized by T-cells 3
Search

SART3

0.93	Squamous cell carcinoma antigen recognized by T-cells 3

0.68	GO:1903584	regulation of histone deubiquitination
0.66	GO:1903003	positive regulation of protein deubiquitination
0.64	GO:0071425	hematopoietic stem cell proliferation
0.63	GO:0006396	RNA processing
0.62	GO:0031058	positive regulation of histone modification
0.59	GO:0006334	nucleosome assembly
0.58	GO:0048872	homeostasis of number of cells
0.55	GO:0022618	ribonucleoprotein complex assembly
0.55	GO:0000902	cell morphogenesis
0.53	GO:0016071	mRNA metabolic process

0.69	GO:0030624	U6atac snRNA binding
0.64	GO:0030621	U4 snRNA binding
0.64	GO:1990381	ubiquitin-specific protease binding
0.63	GO:0017070	U6 snRNA binding
0.59	GO:0042393	histone binding

0.68	GO:0005691	U6atac snRNP
0.66	GO:0071001	U4/U6 snRNP
0.62	GO:0015030	Cajal body
0.42	GO:0071002	U4atac/U6atac snRNP
0.41	GO:0016607	nuclear speck
0.39	GO:0046540	U4/U6 x U5 tri-snRNP complex
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q15021|CND1_HUMAN
Condensin complex subunit 1
Search

NCAPD2

0.73	Condensin complex subunit 1

0.81	GO:0007076	mitotic chromosome condensation
0.63	GO:0051301	cell division
0.50	GO:0010032	meiotic chromosome condensation
0.46	GO:0051304	chromosome separation
0.34	GO:0006006	glucose metabolic process
0.33	GO:0055114	oxidation-reduction process
0.33	GO:0010469	regulation of receptor activity

0.59	GO:0042393	histone binding
0.46	GO:0003682	chromatin binding
0.36	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.34	GO:0050661	NADP binding
0.34	GO:0051287	NAD binding
0.33	GO:0005179	hormone activity
0.32	GO:0003677	DNA binding

0.61	GO:0005634	nucleus
0.61	GO:0000796	condensin complex
0.52	GO:0005829	cytosol
0.52	GO:0031974	membrane-enclosed lumen
0.47	GO:0000779	condensed chromosome, centromeric region
0.33	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.36

EC:1.2.1

GO:0016620

sp|Q15022|SUZ12_HUMAN
Polycomb protein SUZ12
Search

SUZ12

0.95	SUZ12 polycomb repressive complex 2 subunit

0.81	GO:0070734	histone H3-K27 methylation
0.75	GO:0016574	histone ubiquitination
0.73	GO:0045596	negative regulation of cell differentiation
0.71	GO:0008284	positive regulation of cell proliferation
0.70	GO:0000122	negative regulation of transcription by RNA polymerase II
0.41	GO:0070317	negative regulation of G0 to G1 transition
0.40	GO:0006351	transcription, DNA-templated
0.40	GO:0045814	negative regulation of gene expression, epigenetic

0.84	GO:0046976	histone methyltransferase activity (H3-K27 specific)
0.81	GO:0031490	chromatin DNA binding
0.78	GO:1990841	promoter-specific chromatin binding
0.77	GO:0140034	methylation-dependent protein binding
0.73	GO:0042393	histone binding
0.72	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.54	GO:0003723	RNA binding
0.39	GO:0046872	metal ion binding

0.84	GO:0035098	ESC/E(Z) complex
0.81	GO:0001739	sex chromatin
0.72	GO:0016604	nuclear body
0.68	GO:0005730	nucleolus
0.65	GO:0032993	protein-DNA complex
0.64	GO:0016586	RSC-type complex

sp|Q15024|EXOS7_HUMAN
Exosome complex component RRP42
Search

EXOSC7

0.77	Exosome component 7

0.64	GO:0034473	U1 snRNA 3'-end processing
0.63	GO:0071047	polyadenylation-dependent mRNA catabolic process
0.63	GO:0034476	U5 snRNA 3'-end processing
0.62	GO:0034475	U4 snRNA 3'-end processing
0.62	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
0.62	GO:0071038	nuclear polyadenylation-dependent tRNA catabolic process
0.62	GO:0000467	exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.62	GO:0071035	nuclear polyadenylation-dependent rRNA catabolic process
0.61	GO:0071028	nuclear mRNA surveillance
0.61	GO:0034427	nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'

0.62	GO:0017091	AU-rich element binding
0.53	GO:0004527	exonuclease activity
0.40	GO:0004540	ribonuclease activity
0.35	GO:0005515	protein binding

0.72	GO:0000178	exosome (RNase complex)
0.51	GO:0031981	nuclear lumen
0.44	GO:0044444	cytoplasmic part
0.36	GO:0043232	intracellular non-membrane-bounded organelle

sp|Q15025|TNIP1_HUMAN
TNFAIP3-interacting protein 1
Search

TNIP1

0.97	TNFAIP3 interacting protein 1

0.85	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling
0.85	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.84	GO:0002755	MyD88-dependent toll-like receptor signaling pathway
0.82	GO:0050727	regulation of inflammatory response
0.73	GO:0085032	modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade
0.71	GO:1903003	positive regulation of protein deubiquitination
0.68	GO:0007159	leukocyte cell-cell adhesion
0.59	GO:0009101	glycoprotein biosynthetic process
0.51	GO:0071222	cellular response to lipopolysaccharide
0.48	GO:0045944	positive regulation of transcription by RNA polymerase II

0.69	GO:0051019	mitogen-activated protein kinase binding
0.59	GO:0042802	identical protein binding
0.52	GO:0031593	polyubiquitin modification-dependent protein binding

0.56	GO:0005654	nucleoplasm
0.55	GO:0005829	cytosol

sp|Q15027|ACAP1_HUMAN
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
Search

ACAP1

0.80	LOW QUALITY PROTEIN: arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1

0.75	GO:0043547	positive regulation of GTPase activity
0.40	GO:0032515	negative regulation of phosphoprotein phosphatase activity
0.37	GO:0009966	regulation of signal transduction
0.37	GO:0051260	protein homooligomerization
0.35	GO:0007165	signal transduction
0.35	GO:0016042	lipid catabolic process
0.34	GO:0015031	protein transport

0.76	GO:0005096	GTPase activator activity
0.53	GO:0046872	metal ion binding
0.40	GO:0004864	protein phosphatase inhibitor activity
0.35	GO:0004871	signal transducer activity
0.34	GO:0005515	protein binding
0.34	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding
0.33	GO:0016787	hydrolase activity

0.40

GO:0055038

recycling endosome membrane

0.33

GO:0016787

sp|Q15029|U5S1_HUMAN
116 kDa U5 small nuclear ribonucleoprotein component
Search

EFTUD2

0.79	Elongation factor Tu GTP binding domain containing 2

0.52	GO:0043010	camera-type eye development
0.52	GO:0006414	translational elongation
0.52	GO:0045664	regulation of neuron differentiation
0.51	GO:0060322	head development
0.51	GO:0048666	neuron development
0.50	GO:0000398	mRNA splicing, via spliceosome
0.38	GO:0042220	response to cocaine
0.37	GO:0035690	cellular response to drug

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0003746	translation elongation factor activity

0.66	GO:0071007	U2-type catalytic step 2 spliceosome
0.65	GO:0015030	Cajal body
0.62	GO:0046540	U4/U6 x U5 tri-snRNP complex
0.62	GO:0016607	nuclear speck
0.54	GO:0005829	cytosol
0.36	GO:0031012	extracellular matrix
0.30	GO:0016020	membrane

sp|Q15031|SYLM_HUMAN
Probable leucine--tRNA ligase, mitochondrial
Search

LARS2

0.91	Leucyl-tRNA synthetase, mitochondrial

0.78	GO:0006429	leucyl-tRNA aminoacylation
0.72	GO:0106074	aminoacyl-tRNA metabolism involved in translational fidelity
0.48	GO:0032543	mitochondrial translation
0.34	GO:0000376	RNA splicing, via transesterification reactions with guanosine as nucleophile

0.79	GO:0004823	leucine-tRNA ligase activity
0.72	GO:0002161	aminoacyl-tRNA editing activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0003729	mRNA binding

0.47	GO:0005739	mitochondrion
0.36	GO:0043233	organelle lumen
0.35	GO:0044446	intracellular organelle part

0.79	EC:6.1.1.4	GO:0004823
0.79	KEGG:R03657	GO:0004823

sp|Q15032|R3HD1_HUMAN
R3H domain-containing protein 1
Search

R3HDM1

0.95	LOW QUALITY PROTEIN: R3H domain-containing protein 1

0.50

GO:0003676

nucleic acid binding

sp|Q15034|HERC3_HUMAN
Probable E3 ubiquitin-protein ligase HERC3
Search

HERC3

0.91	HECT and RLD domain containing E3 ubiquitin protein ligase 3

0.73

GO:0016567

protein ubiquitination

0.74	GO:0004842	ubiquitin-protein transferase activity
0.52	GO:0061659	ubiquitin-like protein ligase activity
0.38	GO:0016874	ligase activity

0.60

GO:0005829

cytosol

0.38	EC:6	GO:0016874
0.74	KEGG:R03876	GO:0004842

sp|Q15035|TRAM2_HUMAN
Translocating chain-associated membrane protein 2
Search

TRAM2

0.92	Translocating chain-associated membrane protein 2

0.59	GO:0032964	collagen biosynthetic process
0.58	GO:0045184	establishment of protein localization
0.56	GO:0015833	peptide transport
0.55	GO:0007029	endoplasmic reticulum organization
0.50	GO:0033365	protein localization to organelle
0.50	GO:0072657	protein localization to membrane
0.48	GO:0061024	membrane organization

0.34	GO:0005515	protein binding
0.33	GO:0005509	calcium ion binding

0.30

GO:0016020

membrane

sp|Q15036|SNX17_HUMAN
Sorting nexin-17
Search

SNX17

0.95	Sorting nexin-17 isoform A

0.69	GO:0006886	intracellular protein transport
0.59	GO:0060976	coronary vasculature development
0.59	GO:0007165	signal transduction
0.59	GO:0035904	aorta development
0.58	GO:0003279	cardiac septum development
0.51	GO:0006898	receptor-mediated endocytosis
0.48	GO:1990126	retrograde transport, endosome to plasma membrane
0.36	GO:0006707	cholesterol catabolic process
0.35	GO:0030100	regulation of endocytosis

0.76	GO:0035091	phosphatidylinositol binding
0.59	GO:0050750	low-density lipoprotein particle receptor binding
0.57	GO:0008022	protein C-terminus binding

0.57	GO:0005769	early endosome
0.54	GO:0010008	endosome membrane
0.51	GO:0005794	Golgi apparatus
0.50	GO:0005829	cytosol
0.45	GO:0043234	protein complex
0.40	GO:0030659	cytoplasmic vesicle membrane
0.34	GO:0005856	cytoskeleton
0.30	GO:0031224	intrinsic component of membrane

sp|Q15038|DAZP2_HUMAN
DAZ-associated protein 2
Search

DAZAP2

0.94	DAZ-associated protein 2

0.76	GO:0050699	WW domain binding
0.65	GO:0042802	identical protein binding

0.72	GO:0016607	nuclear speck
0.53	GO:0043234	protein complex
0.45	GO:0005737	cytoplasm

sp|Q15040|JOS1_HUMAN
Josephin-1
Search

JOSD1

0.97	Josephin domain containing 1

0.76	GO:0016579	protein deubiquitination
0.46	GO:1904888	cranial skeletal system development
0.39	GO:0021551	central nervous system morphogenesis

0.80	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.33	GO:0005515	protein binding

0.35	GO:0005886	plasma membrane
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q15041|AR6P1_HUMAN
ADP-ribosylation factor-like protein 6-interacting protein 1
Search

ARL6IP1

0.96	ADP ribosylation factor like GTPase 6 interacting protein 1

0.57	GO:0002038	positive regulation of L-glutamate transport
0.52	GO:0006613	cotranslational protein targeting to membrane
0.44	GO:0071787	endoplasmic reticulum tubular network formation
0.44	GO:1990809	endoplasmic reticulum tubular network membrane organization
0.43	GO:0001755	neural crest cell migration
0.43	GO:0060042	retina morphogenesis in camera-type eye
0.42	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.37	GO:0006915	apoptotic process
0.36	GO:0006518	peptide metabolic process
0.36	GO:0043604	amide biosynthetic process

0.40	GO:0042802	identical protein binding
0.37	GO:0003735	structural constituent of ribosome
0.32	GO:0003723	RNA binding
0.32	GO:0046872	metal ion binding
0.32	GO:0004674	protein serine/threonine kinase activity
0.31	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.56	GO:0005784	Sec61 translocon complex
0.45	GO:0005829	cytosol
0.41	GO:0030176	integral component of endoplasmic reticulum membrane
0.37	GO:0005840	ribosome

0.32

GO:0004674

sp|Q15042|RB3GP_HUMAN
Rab3 GTPase-activating protein catalytic subunit
Search

RAB3GAP1

0.90	LOW QUALITY PROTEIN: rab3 GTPase-activating protein catalytic subunit

0.74	GO:0043547	positive regulation of GTPase activity
0.61	GO:0061646	positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization
0.61	GO:1903233	regulation of calcium ion-dependent exocytosis of neurotransmitter
0.60	GO:1903373	positive regulation of endoplasmic reticulum tubular network organization
0.60	GO:0097051	establishment of protein localization to endoplasmic reticulum membrane
0.60	GO:1903061	positive regulation of protein lipidation
0.59	GO:2000786	positive regulation of autophagosome assembly
0.59	GO:0048172	regulation of short-term neuronal synaptic plasticity
0.58	GO:0021854	hypothalamus development
0.58	GO:0060325	face morphogenesis

0.75	GO:0005096	GTPase activator activity
0.56	GO:0017112	Rab guanyl-nucleotide exchange factor activity
0.34	GO:0046982	protein heterodimerization activity

0.57	GO:0071782	endoplasmic reticulum tubular network
0.55	GO:0005811	lipid droplet
0.53	GO:0098794	postsynapse
0.50	GO:0005794	Golgi apparatus
0.44	GO:0043234	protein complex
0.36	GO:0070062	extracellular exosome
0.35	GO:0060076	excitatory synapse
0.34	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q15043|S39AE_HUMAN
Zinc transporter ZIP14
Search

SLC39A14

0.95	LOW QUALITY PROTEIN: zinc transporter ZIP14

0.66	GO:0030001	metal ion transport
0.59	GO:0006882	cellular zinc ion homeostasis
0.55	GO:0055085	transmembrane transport
0.52	GO:0072511	divalent inorganic cation transport
0.43	GO:0055071	manganese ion homeostasis
0.36	GO:0031047	gene silencing by RNA
0.34	GO:0006470	protein dephosphorylation

0.68	GO:0046873	metal ion transmembrane transporter activity
0.54	GO:0072509	divalent inorganic cation transmembrane transporter activity
0.34	GO:0004721	phosphoprotein phosphatase activity
0.33	GO:0003676	nucleic acid binding

0.49	GO:0005887	integral component of plasma membrane
0.41	GO:0030027	lamellipodium
0.39	GO:0005737	cytoplasm
0.35	GO:0031090	organelle membrane

0.34

GO:0004721

sp|Q15046|SYK_HUMAN
Lysine--tRNA ligase
Search

KARS

0.54	Lysine--tRNA ligase

0.76	GO:0006430	lysyl-tRNA aminoacylation
0.57	GO:0002276	basophil activation involved in immune response
0.56	GO:0015960	diadenosine polyphosphate biosynthetic process
0.56	GO:0015965	diadenosine tetraphosphate metabolic process
0.55	GO:1905050	positive regulation of metallopeptidase activity
0.55	GO:0002741	positive regulation of cytokine secretion involved in immune response
0.54	GO:0010759	positive regulation of macrophage chemotaxis
0.54	GO:1900017	positive regulation of cytokine production involved in inflammatory response
0.54	GO:0043032	positive regulation of macrophage activation
0.54	GO:1900745	positive regulation of p38MAPK cascade

0.77	GO:0004824	lysine-tRNA ligase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0003877	ATP adenylyltransferase activity
0.50	GO:0003676	nucleic acid binding
0.48	GO:0042803	protein homodimerization activity
0.37	GO:0097110	scaffold protein binding
0.37	GO:0016597	amino acid binding

0.54	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex
0.48	GO:0005737	cytoplasm
0.47	GO:0005615	extracellular space
0.43	GO:0005634	nucleus
0.34	GO:0005886	plasma membrane
0.33	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

0.77

EC:6.1.1.6

GO:0004824

sp|Q15047|SETB1_HUMAN
Histone-lysine N-methyltransferase SETDB1
Search

SETDB1

0.50	Histone-lysine N-methyltransferase

0.77	GO:0034968	histone lysine methylation
0.68	GO:0090309	positive regulation of methylation-dependent chromatin silencing
0.62	GO:0007265	Ras protein signal transduction
0.43	GO:0033273	response to vitamin
0.42	GO:0045471	response to ethanol
0.42	GO:0001833	inner cell mass cell proliferation
0.41	GO:0061647	histone H3-K9 modification
0.41	GO:0018023	peptidyl-lysine trimethylation
0.40	GO:0060348	bone development
0.39	GO:0000122	negative regulation of transcription by RNA polymerase II

0.78	GO:0018024	histone-lysine N-methyltransferase activity
0.65	GO:1990841	promoter-specific chromatin binding
0.62	GO:0008270	zinc ion binding
0.54	GO:0003677	DNA binding
0.36	GO:0005515	protein binding
0.31	GO:0003700	DNA binding transcription factor activity

0.64	GO:0005694	chromosome
0.60	GO:0005634	nucleus
0.54	GO:0005829	cytosol
0.53	GO:0031974	membrane-enclosed lumen
0.47	GO:0044446	intracellular organelle part
0.46	GO:0005886	plasma membrane
0.32	GO:0005667	transcription factor complex
0.30	GO:0031224	intrinsic component of membrane

0.78

GO:0018024

sp|Q15048|LRC14_HUMAN
Leucine-rich repeat-containing protein 14
Search

LRRC14

0.97	LOW QUALITY PROTEIN: leucine-rich repeat-containing protein 14

0.86	GO:0034122	negative regulation of toll-like receptor signaling pathway
0.85	GO:0032088	negative regulation of NF-kappaB transcription factor activity

0.78

GO:0019900

kinase binding

0.49

GO:0005737

cytoplasm

sp|Q15049|MLC1_HUMAN
Membrane protein MLC1
Search

MLC1

0.96	Membrane protein MLC1

0.48	GO:0047484	regulation of response to osmotic stress
0.46	GO:0032388	positive regulation of intracellular transport
0.45	GO:0071397	cellular response to cholesterol
0.43	GO:0051259	protein oligomerization
0.43	GO:0072584	caveolin-mediated endocytosis
0.39	GO:0008104	protein localization
0.39	GO:0042886	amide transport
0.38	GO:0071702	organic substance transport
0.37	GO:0006811	ion transport
0.34	GO:0070727	cellular macromolecule localization

0.44	GO:0032403	protein complex binding
0.40	GO:0008565	protein transporter activity
0.36	GO:0005216	ion channel activity

0.46	GO:0016323	basolateral plasma membrane
0.46	GO:0016324	apical plasma membrane
0.45	GO:0048471	perinuclear region of cytoplasm
0.45	GO:0005911	cell-cell junction
0.44	GO:0005768	endosome
0.43	GO:0005901	caveola
0.43	GO:0005783	endoplasmic reticulum
0.42	GO:0005764	lysosome
0.40	GO:0030136	clathrin-coated vesicle
0.30	GO:0016021	integral component of membrane

sp|Q15050|RRS1_HUMAN
Ribosome biogenesis regulatory protein homolog
Search

RRS1

0.72	Ribosome biogenesis regulatory protein homolog

0.66	GO:0042254	ribosome biogenesis
0.59	GO:1902570	protein localization to nucleolus
0.56	GO:1901796	regulation of signal transduction by p53 class mediator
0.55	GO:0007080	mitotic metaphase plate congression
0.50	GO:0022618	ribonucleoprotein complex assembly
0.49	GO:0070925	organelle assembly
0.47	GO:0033750	ribosome localization
0.47	GO:0071428	rRNA-containing ribonucleoprotein complex export from nucleus
0.45	GO:0002244	hematopoietic progenitor cell differentiation
0.43	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic

0.53	GO:0008097	5S rRNA binding
0.32	GO:0016491	oxidoreductase activity
0.32	GO:0046872	metal ion binding
0.32	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.51	GO:0000793	condensed chromosome
0.48	GO:0031974	membrane-enclosed lumen
0.47	GO:0030687	preribosome, large subunit precursor
0.43	GO:0044446	intracellular organelle part
0.41	GO:0005783	endoplasmic reticulum

0.32

EC:1

GO:0016491

sp|Q15051|IQCB1_HUMAN
IQ calmodulin-binding motif-containing protein 1
Search

IQCB1

0.97	IQ calmodulin-binding motif-containing protein 1

0.80	GO:0060271	cilium assembly
0.70	GO:0048496	maintenance of animal organ identity
0.67	GO:0045494	photoreceptor cell maintenance
0.37	GO:0036372	opsin transport
0.37	GO:0140056	organelle localization by membrane tethering
0.36	GO:0048793	pronephros development

0.79	GO:0005516	calmodulin binding
0.57	GO:0019899	enzyme binding

0.67	GO:0032391	photoreceptor connecting cilium
0.66	GO:0045171	intercellular bridge
0.65	GO:0001750	photoreceptor outer segment
0.63	GO:0072686	mitotic spindle
0.61	GO:0005813	centrosome
0.56	GO:0005654	nucleoplasm
0.39	GO:0070062	extracellular exosome
0.37	GO:0005814	centriole
0.35	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q15052|ARHG6_HUMAN
Rho guanine nucleotide exchange factor 6
Search

ARHGEF6

0.97	Rho guanine nucleotide exchange factor 6

0.77	GO:0035023	regulation of Rho protein signal transduction
0.66	GO:0065009	regulation of molecular function
0.59	GO:0035556	intracellular signal transduction
0.41	GO:0030032	lamellipodium assembly
0.37	GO:0043065	positive regulation of apoptotic process
0.36	GO:0060124	positive regulation of growth hormone secretion
0.35	GO:0002244	hematopoietic progenitor cell differentiation
0.35	GO:0007030	Golgi organization
0.35	GO:0006915	apoptotic process
0.34	GO:0007186	G-protein coupled receptor signaling pathway

0.78	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.35	GO:0019901	protein kinase binding
0.35	GO:0005096	GTPase activator activity

0.44	GO:0005622	intracellular
0.41	GO:0030027	lamellipodium
0.36	GO:0005911	cell-cell junction
0.35	GO:0043025	neuronal cell body
0.35	GO:0043005	neuron projection
0.33	GO:0043234	protein complex
0.33	GO:0043227	membrane-bounded organelle
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q15053|K0040_HUMAN
Uncharacterized protein KIAA0040
Search

sp|Q15054|DPOD3_HUMAN
DNA polymerase delta subunit 3
Search

POLD3

0.95	DNA-directed polymerase delta 3 accessory subunit

0.65	GO:0006260	DNA replication
0.64	GO:0006297	nucleotide-excision repair, DNA gap filling
0.37	GO:0042769	DNA damage response, detection of DNA damage
0.37	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion
0.36	GO:0019985	translesion synthesis
0.36	GO:0006283	transcription-coupled nucleotide-excision repair
0.36	GO:0000723	telomere maintenance
0.35	GO:0006266	DNA ligation
0.35	GO:0006298	mismatch repair
0.35	GO:0022402	cell cycle process

0.36	GO:0003887	DNA-directed DNA polymerase activity
0.34	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.38	GO:0030894	replisome
0.38	GO:0042575	DNA polymerase complex
0.38	GO:0043233	organelle lumen
0.34	GO:0005737	cytoplasm

0.36

EC:2.7.7.7

GO:0003887

sp|Q15056|IF4H_HUMAN
Eukaryotic translation initiation factor 4H
Search

EIF4H

0.92	Eukaryotic translation initiation factor 4H

0.64	GO:0006413	translational initiation
0.49	GO:0048589	developmental growth
0.48	GO:0097010	eukaryotic translation initiation factor 4F complex assembly
0.48	GO:0019953	sexual reproduction
0.45	GO:0002181	cytoplasmic translation
0.44	GO:0022618	ribonucleoprotein complex assembly
0.35	GO:0006446	regulation of translational initiation
0.33	GO:0016032	viral process

0.64	GO:0003743	translation initiation factor activity
0.51	GO:0045296	cadherin binding
0.48	GO:0043024	ribosomal small subunit binding
0.48	GO:0034057	RNA strand-exchange activity
0.48	GO:0033592	RNA strand annealing activity
0.34	GO:0004386	helicase activity

0.49	GO:0016281	eukaryotic translation initiation factor 4F complex
0.47	GO:0005844	polysome
0.39	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|Q15057|ACAP2_HUMAN
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2
Search

ACAP2

0.84	Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2

0.75	GO:0043547	positive regulation of GTPase activity
0.41	GO:1990090	cellular response to nerve growth factor stimulus
0.41	GO:0036010	protein localization to endosome
0.34	GO:0030029	actin filament-based process
0.33	GO:0043043	peptide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process

0.76	GO:0005096	GTPase activator activity
0.53	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding
0.51	GO:0017137	Rab GTPase binding
0.51	GO:0046872	metal ion binding
0.33	GO:0003735	structural constituent of ribosome

0.39	GO:0010008	endosome membrane
0.35	GO:0001726	ruffle
0.33	GO:0005840	ribosome

sp|Q15058|KIF14_HUMAN
Kinesin-like protein KIF14
Search

KIF14

0.97	Kinesin family member 14

0.80	GO:0021685	cerebellar granular layer structural organization
0.79	GO:0032487	regulation of Rap protein signal transduction
0.78	GO:0033624	negative regulation of integrin activation
0.78	GO:0021693	cerebellar Purkinje cell layer structural organization
0.74	GO:0031641	regulation of myelination
0.74	GO:0007018	microtubule-based movement
0.74	GO:0021846	cell proliferation in forebrain
0.74	GO:0021772	olfactory bulb development
0.73	GO:1903429	regulation of cell maturation
0.73	GO:0034446	substrate adhesion-dependent cell spreading

0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.72	GO:0030165	PDZ domain binding
0.66	GO:0019901	protein kinase binding
0.55	GO:0042623	ATPase activity, coupled
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.74	GO:0090543	Flemming body
0.71	GO:0051233	spindle midzone
0.62	GO:0005874	microtubule
0.59	GO:0005829	cytosol
0.55	GO:0005871	kinesin complex
0.49	GO:0005886	plasma membrane

sp|Q15059|BRD3_HUMAN
Bromodomain-containing protein 3
Search

BRD3

0.92	Bromodomain-containing protein 3

0.74	GO:0016569	covalent chromatin modification
0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.58	GO:0097659	nucleic acid-templated transcription
0.54	GO:0010467	gene expression
0.53	GO:0034645	cellular macromolecule biosynthetic process

0.85	GO:0140033	acetylation-dependent protein binding
0.80	GO:0042393	histone binding
0.77	GO:0003682	chromatin binding

0.61

GO:0005634

nucleus

sp|Q15061|WDR43_HUMAN
WD repeat-containing protein 43
Search

WDR43

0.94	LOW QUALITY PROTEIN: WD repeat-containing protein 43

0.84	GO:2000234	positive regulation of rRNA processing
0.80	GO:0045943	positive regulation of transcription by RNA polymerase I
0.56	GO:0060218	hematopoietic stem cell differentiation
0.56	GO:0048703	embryonic viscerocranium morphogenesis
0.55	GO:0001570	vasculogenesis
0.53	GO:0001525	angiogenesis
0.49	GO:0042254	ribosome biogenesis
0.39	GO:0016072	rRNA metabolic process
0.38	GO:0034470	ncRNA processing
0.37	GO:0006351	transcription, DNA-templated

0.37	GO:0003723	RNA binding
0.36	GO:0005515	protein binding
0.32	GO:0043531	ADP binding
0.31	GO:0005524	ATP binding

0.78	GO:0001650	fibrillar center
0.37	GO:0005654	nucleoplasm
0.32	GO:0043293	apoptosome
0.30	GO:0031224	intrinsic component of membrane

sp|Q15063|POSTN_HUMAN
Periostin
Search

POSTN

0.93	Periostin, osteoblast specific factor b

0.87	GO:0071307	cellular response to vitamin K
0.79	GO:0008593	regulation of Notch signaling pathway
0.77	GO:0030198	extracellular matrix organization
0.72	GO:0007155	cell adhesion
0.71	GO:0009888	tissue development
0.54	GO:1904207	regulation of chemokine (C-C motif) ligand 2 secretion
0.52	GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production
0.51	GO:0090197	positive regulation of chemokine secretion
0.51	GO:0014850	response to muscle activity
0.51	GO:0014911	positive regulation of smooth muscle cell migration

0.78	GO:0008201	heparin binding
0.53	GO:0046872	metal ion binding
0.37	GO:0005515	protein binding

0.77	GO:0005802	trans-Golgi network
0.74	GO:0031012	extracellular matrix
0.70	GO:0005615	extracellular space
0.49	GO:0031594	neuromuscular junction
0.30	GO:0016020	membrane

sp|Q15067|ACOX1_HUMAN
Peroxisomal acyl-coenzyme A oxidase 1
Search

ACOX1

0.61	Acyl-coenzyme A oxidase

0.76	GO:0006635	fatty acid beta-oxidation
0.58	GO:0006692	prostanoid metabolic process
0.55	GO:0000038	very long-chain fatty acid metabolic process
0.52	GO:0007283	spermatogenesis
0.45	GO:0006091	generation of precursor metabolites and energy
0.40	GO:2000189	positive regulation of cholesterol homeostasis
0.38	GO:0016559	peroxisome fission
0.38	GO:0055088	lipid homeostasis
0.36	GO:0036109	alpha-linolenic acid metabolic process
0.35	GO:0019216	regulation of lipid metabolic process

0.82	GO:0003997	acyl-CoA oxidase activity
0.72	GO:0071949	FAD binding
0.56	GO:0047485	protein N-terminus binding
0.56	GO:0030165	PDZ domain binding
0.50	GO:0005102	receptor binding
0.43	GO:0003995	acyl-CoA dehydrogenase activity
0.35	GO:0005504	fatty acid binding
0.34	GO:0042803	protein homodimerization activity

0.75	GO:0005777	peroxisome
0.52	GO:0031903	microbody membrane
0.50	GO:0005730	nucleolus
0.48	GO:0005654	nucleoplasm
0.44	GO:0005739	mitochondrion
0.42	GO:0005886	plasma membrane
0.35	GO:0031907	microbody lumen

0.82

EC:1.3.3.6

GO:0003997

sp|Q15070|OXA1L_HUMAN
Mitochondrial inner membrane protein OXA1L
Search

OXA1L

0.96	Mitochondrial inner membrane protein OXA1L

0.76	GO:0051205	protein insertion into membrane
0.41	GO:0097031	mitochondrial respiratory chain complex I biogenesis
0.41	GO:0033615	mitochondrial proton-transporting ATP synthase complex assembly
0.41	GO:0051354	negative regulation of oxidoreductase activity
0.40	GO:0051262	protein tetramerization
0.40	GO:0010257	NADH dehydrogenase complex assembly
0.39	GO:0032780	negative regulation of ATPase activity
0.39	GO:0033108	mitochondrial respiratory chain complex assembly
0.36	GO:0009060	aerobic respiration
0.34	GO:0016579	protein deubiquitination

0.43	GO:0097177	mitochondrial ribosome binding
0.39	GO:0042803	protein homodimerization activity
0.34	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity

0.47	GO:0031966	mitochondrial membrane
0.47	GO:0019866	organelle inner membrane
0.38	GO:0031301	integral component of organelle membrane
0.36	GO:0043234	protein complex
0.34	GO:0070469	respiratory chain

0.34

EC:3.4.19.12

GO:0036459

sp|Q15072|OZF_HUMAN
Zinc finger protein OZF
Search

0.60	Zinc finger protein OZF

0.48	GO:1903506	regulation of nucleic acid-templated transcription
0.48	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.48	GO:0010468	regulation of gene expression
0.38	GO:0007275	multicellular organism development
0.37	GO:0006351	transcription, DNA-templated

0.51	GO:0003676	nucleic acid binding
0.46	GO:0003700	DNA binding transcription factor activity
0.44	GO:0046872	metal ion binding
0.36	GO:0008201	heparin binding
0.34	GO:0005515	protein binding

0.53	GO:0005829	cytosol
0.53	GO:0031981	nuclear lumen
0.42	GO:0043232	intracellular non-membrane-bounded organelle

sp|Q15075|EEA1_HUMAN
Early endosome antigen 1
Search

EEA1

0.96	Early endosome antigen 1

0.53	GO:0006906	vesicle fusion
0.48	GO:0006897	endocytosis
0.48	GO:0039694	viral RNA genome replication
0.37	GO:0016189	synaptic vesicle to endosome fusion
0.36	GO:0045022	early endosome to late endosome transport

0.57	GO:0030742	GTP-dependent protein binding
0.54	GO:0005545	1-phosphatidylinositol binding
0.52	GO:0046872	metal ion binding
0.50	GO:0042803	protein homodimerization activity
0.45	GO:0003676	nucleic acid binding
0.35	GO:0005516	calmodulin binding

0.55	GO:0005969	serine-pyruvate aminotransferase complex
0.54	GO:0044308	axonal spine
0.53	GO:0005769	early endosome
0.51	GO:0019897	extrinsic component of plasma membrane
0.47	GO:0005829	cytosol
0.39	GO:0055037	recycling endosome
0.37	GO:0070062	extracellular exosome
0.37	GO:0010008	endosome membrane
0.35	GO:0098793	presynapse

sp|Q15077|P2RY6_HUMAN
P2Y purinoceptor 6
Search

P2RY6

0.97	Pyrimidinergic receptor P2Y, G-protein coupled, 6

0.83	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway
0.65	GO:0030321	transepithelial chloride transport
0.63	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway
0.60	GO:0071380	cellular response to prostaglandin E stimulus
0.54	GO:0071407	cellular response to organic cyclic compound
0.43	GO:0014911	positive regulation of smooth muscle cell migration
0.40	GO:0070257	positive regulation of mucus secretion
0.39	GO:0097746	regulation of blood vessel diameter
0.34	GO:0060406	positive regulation of penile erection
0.34	GO:0032308	positive regulation of prostaglandin secretion

0.83	GO:0045028	G-protein coupled purinergic nucleotide receptor activity
0.63	GO:0045029	UDP-activated nucleotide receptor activity
0.36	GO:0019103	pyrimidine nucleotide binding
0.36	GO:0045030	UTP-activated nucleotide receptor activity
0.34	GO:0031686	A1 adenosine receptor binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.42	GO:0016323	basolateral plasma membrane
0.42	GO:0016324	apical plasma membrane
0.34	GO:0005887	integral component of plasma membrane
0.33	GO:0005769	early endosome
0.33	GO:0005764	lysosome
0.32	GO:0005739	mitochondrion

sp|Q15078|CD5R1_HUMAN
Cyclin-dependent kinase 5 activator 1
Search

CDK5R1

0.95	Cyclin-dependent kinase 5 activator

0.80	GO:0071902	positive regulation of protein serine/threonine kinase activity
0.61	GO:0021722	superior olivary nucleus maturation
0.60	GO:0042501	serine phosphorylation of STAT protein
0.58	GO:0021819	layer formation in cerebral cortex
0.58	GO:0007158	neuron cell-cell adhesion
0.57	GO:0061001	regulation of dendritic spine morphogenesis
0.57	GO:0090314	positive regulation of protein targeting to membrane
0.57	GO:0030517	negative regulation of axon extension
0.57	GO:0007413	axonal fasciculation
0.57	GO:0021766	hippocampus development

0.86	GO:0016534	cyclin-dependent protein kinase 5 activator activity
0.58	GO:0035255	ionotropic glutamate receptor binding
0.55	GO:0002020	protease binding
0.53	GO:0019901	protein kinase binding
0.52	GO:0051015	actin filament binding
0.51	GO:0016301	kinase activity
0.41	GO:0045296	cadherin binding
0.40	GO:0046875	ephrin receptor binding
0.38	GO:0005509	calcium ion binding
0.38	GO:0043014	alpha-tubulin binding

0.86	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex
0.53	GO:0048471	perinuclear region of cytoplasm
0.49	GO:0005654	nucleoplasm
0.42	GO:0014069	postsynaptic density
0.42	GO:0030426	growth cone
0.41	GO:0043197	dendritic spine
0.41	GO:0031594	neuromuscular junction
0.41	GO:0043025	neuronal cell body
0.41	GO:0030424	axon
0.40	GO:0043292	contractile fiber

0.33

GO:0016773

sp|Q15080|NCF4_HUMAN
Neutrophil cytosol factor 4
Search

NCF4

0.97	Neutrophil cytosolic factor 4 variant

0.86	GO:0045730	respiratory burst
0.83	GO:0006909	phagocytosis
0.73	GO:0043085	positive regulation of catalytic activity
0.36	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.36	GO:0048010	vascular endothelial growth factor receptor signaling pathway
0.35	GO:0034599	cellular response to oxidative stress
0.35	GO:0006955	immune response
0.34	GO:0045454	cell redox homeostasis
0.33	GO:0055114	oxidation-reduction process
0.32	GO:0007264	small GTPase mediated signal transduction

0.86	GO:0016176	superoxide-generating NADPH oxidase activator activity
0.76	GO:0035091	phosphatidylinositol binding
0.47	GO:0005086	ARF guanyl-nucleotide exchange factor activity
0.34	GO:0046983	protein dimerization activity
0.32	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.31	GO:0046872	metal ion binding

0.85	GO:0043020	NADPH oxidase complex
0.53	GO:0010008	endosome membrane
0.49	GO:0005829	cytosol
0.46	GO:0005802	trans-Golgi network
0.36	GO:0032010	phagolysosome

sp|Q15084|PDIA6_HUMAN
Protein disulfide-isomerase A6
Search

PDIA6

0.81	Disulfide-isomerase A6

0.68	GO:0045454	cell redox homeostasis
0.45	GO:0043277	apoptotic cell clearance
0.43	GO:0034976	response to endoplasmic reticulum stress
0.42	GO:0070527	platelet aggregation
0.41	GO:0006457	protein folding
0.39	GO:0055114	oxidation-reduction process
0.30	GO:0035966	response to topologically incorrect protein
0.30	GO:0043687	post-translational protein modification
0.30	GO:0070887	cellular response to chemical stimulus
0.30	GO:0007165	signal transduction

0.63	GO:0016853	isomerase activity
0.51	GO:0015037	peptide disulfide oxidoreductase activity
0.39	GO:0140096	catalytic activity, acting on a protein
0.35	GO:0005509	calcium ion binding
0.34	GO:0005515	protein binding

0.52	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.48	GO:0005615	extracellular space
0.48	GO:0005783	endoplasmic reticulum
0.45	GO:0005829	cytosol
0.41	GO:0042470	melanosome
0.38	GO:0043233	organelle lumen
0.36	GO:1903561	extracellular vesicle
0.36	GO:0044446	intracellular organelle part
0.35	GO:0005886	plasma membrane
0.35	GO:0043234	protein complex

0.63

GO:0016853

sp|Q15102|PA1B3_HUMAN
Platelet-activating factor acetylhydrolase IB subunit gamma
Search

PAFAH1B3

0.89	Platelet-activating factor acetylhydrolase IB subunit gamma

0.59	GO:0007283	spermatogenesis
0.50	GO:0016239	positive regulation of macroautophagy
0.49	GO:0007420	brain development
0.42	GO:0016042	lipid catabolic process
0.35	GO:0043312	neutrophil degranulation

0.56	GO:0047179	platelet-activating factor acetyltransferase activity
0.51	GO:0042802	identical protein binding
0.46	GO:0016787	hydrolase activity
0.39	GO:0046982	protein heterodimerization activity

0.49	GO:0001650	fibrillar center
0.45	GO:0005829	cytosol
0.39	GO:0005886	plasma membrane
0.39	GO:0070062	extracellular exosome
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen

0.56

EC:2.3.1.149

GO:0047179

sp|Q15109|RAGE_HUMAN
Advanced glycosylation end product-specific receptor
Search

AGER

0.96	Advanced glycosylation end product-specific receptor variant AA

0.65	GO:1904597	negative regulation of connective tissue replacement involved in inflammatory response wound healing
0.65	GO:1904603	regulation of advanced glycation end-product receptor activity
0.64	GO:1900453	negative regulation of long term synaptic depression
0.64	GO:2001200	positive regulation of dendritic cell differentiation
0.64	GO:0061890	positive regulation of astrocyte activation
0.64	GO:0150003	regulation of spontaneous synaptic transmission
0.63	GO:1903980	positive regulation of microglial cell activation
0.63	GO:1900272	negative regulation of long-term synaptic potentiation
0.63	GO:0090647	modulation of age-related behavioral decline
0.63	GO:0071639	positive regulation of monocyte chemotactic protein-1 production

0.65	GO:1904599	advanced glycation end-product binding
0.61	GO:0044548	S100 protein binding
0.58	GO:0008201	heparin binding
0.53	GO:0042802	identical protein binding
0.49	GO:0038023	signaling receptor activity
0.37	GO:0070379	high mobility group box 1 binding
0.37	GO:0001540	amyloid-beta binding
0.36	GO:0005044	scavenger receptor activity
0.35	GO:0099600	transmembrane receptor activity

0.58	GO:0001650	fibrillar center
0.57	GO:0016324	apical plasma membrane
0.54	GO:0030054	cell junction
0.49	GO:0005576	extracellular region
0.39	GO:0009986	cell surface
0.36	GO:0009925	basal plasma membrane
0.36	GO:0098794	postsynapse
0.36	GO:0043025	neuronal cell body
0.36	GO:0030424	axon
0.35	GO:0098552	side of membrane

sp|Q15111|PLCL1_HUMAN
Inactive phospholipase C-like protein 1
Search

PLCL1

0.53	Phosphoinositide phospholipase C

0.85	GO:0032228	regulation of synaptic transmission, GABAergic
0.71	GO:0016042	lipid catabolic process
0.63	GO:0035556	intracellular signal transduction
0.60	GO:1900122	positive regulation of receptor binding
0.58	GO:0007214	gamma-aminobutyric acid signaling pathway
0.57	GO:0033135	regulation of peptidyl-serine phosphorylation
0.49	GO:0002337	B-1a B cell differentiation
0.48	GO:0050859	negative regulation of B cell receptor signaling pathway
0.48	GO:0002322	B cell proliferation involved in immune response

0.86	GO:0050811	GABA receptor binding
0.85	GO:0070679	inositol 1,4,5 trisphosphate binding
0.82	GO:0004435	phosphatidylinositol phospholipase C activity
0.64	GO:0004871	signal transducer activity
0.36	GO:0005509	calcium ion binding

0.45	GO:0005622	intracellular
0.40	GO:0005886	plasma membrane

0.82	EC:3.1.4.11	GO:0004435
0.82	KEGG:R03435	GO:0004435

sp|Q15113|PCOC1_HUMAN
Procollagen C-endopeptidase enhancer 1
Search

PCOLCE

0.94	Procollagen C-endopeptidase enhancer a

0.76	GO:0010952	positive regulation of peptidase activity
0.54	GO:1990830	cellular response to leukemia inhibitory factor
0.44	GO:0006508	proteolysis
0.35	GO:0007275	multicellular organism development

0.78	GO:0016504	peptidase activator activity
0.77	GO:0005518	collagen binding
0.77	GO:0008201	heparin binding
0.32	GO:0008233	peptidase activity

0.68	GO:0005615	extracellular space
0.50	GO:0031012	extracellular matrix
0.42	GO:0005581	collagen trimer
0.37	GO:1903561	extracellular vesicle
0.30	GO:0016020	membrane

0.32

GO:0008233

sp|Q15116|PDCD1_HUMAN
Programmed cell death protein 1
Search

PDCD1

0.97	Programmed cell death protein 1

0.71	GO:0070234	positive regulation of T cell apoptotic process
0.55	GO:0002644	negative regulation of tolerance induction
0.48	GO:0043066	negative regulation of apoptotic process
0.40	GO:0006915	apoptotic process
0.40	GO:0031295	T cell costimulation
0.39	GO:0006959	humoral immune response
0.37	GO:0007275	multicellular organism development
0.35	GO:0007165	signal transduction

0.37	GO:0005515	protein binding
0.36	GO:0004871	signal transducer activity

0.49	GO:0009897	external side of plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q15118|PDK1_HUMAN
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial
Search

PDK1

0.83	Pyruvate dehydrogenase kinase

0.66	GO:0097411	hypoxia-inducible factor-1alpha signaling pathway
0.64	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate
0.63	GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress
0.60	GO:0010906	regulation of glucose metabolic process
0.58	GO:0008283	cell proliferation
0.57	GO:0016310	phosphorylation
0.47	GO:0036211	protein modification process
0.44	GO:0044267	cellular protein metabolic process
0.38	GO:0006006	glucose metabolic process
0.35	GO:0007166	cell surface receptor signaling pathway

0.64	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity
0.37	GO:0005515	protein binding
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0044877	macromolecular complex binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0004674	protein serine/threonine kinase activity

0.60	GO:0005967	mitochondrial pyruvate dehydrogenase complex
0.54	GO:0005730	nucleolus
0.33	GO:0005886	plasma membrane

0.64

EC:2.7.11.2

GO:0004740

sp|Q15119|PDK2_HUMAN
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial
Search

PDK2

0.95	Pyruvate dehydrogenase (Acetyl-transferring) kinase isozyme 2, mitochondrial

0.63	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate
0.58	GO:0008286	insulin receptor signaling pathway
0.58	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator
0.58	GO:0010906	regulation of glucose metabolic process
0.57	GO:0031670	cellular response to nutrient
0.57	GO:0043255	regulation of carbohydrate biosynthetic process
0.55	GO:0042593	glucose homeostasis
0.55	GO:0016310	phosphorylation
0.55	GO:0006885	regulation of pH
0.53	GO:0034599	cellular response to oxidative stress

0.62	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity
0.52	GO:0042803	protein homodimerization activity
0.42	GO:0032559	adenyl ribonucleotide binding
0.42	GO:0008144	drug binding
0.42	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0032403	protein complex binding
0.35	GO:0046982	protein heterodimerization activity
0.34	GO:0004674	protein serine/threonine kinase activity

0.60	GO:0005967	mitochondrial pyruvate dehydrogenase complex
0.50	GO:0005654	nucleoplasm
0.49	GO:0005829	cytosol
0.36	GO:0005730	nucleolus
0.35	GO:0008305	integrin complex

0.62

EC:2.7.11.2

GO:0004740

sp|Q15120|PDK3_HUMAN
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial
Search

PDK3

0.97	Pyruvate dehydrogenase kinase 3

0.67	GO:0097411	hypoxia-inducible factor-1alpha signaling pathway
0.66	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate
0.66	GO:0035357	peroxisome proliferator activated receptor signaling pathway
0.63	GO:0071398	cellular response to fatty acid
0.61	GO:2000377	regulation of reactive oxygen species metabolic process
0.61	GO:0010906	regulation of glucose metabolic process
0.60	GO:0018105	peptidyl-serine phosphorylation
0.39	GO:0071333	cellular response to glucose stimulus
0.37	GO:0006006	glucose metabolic process
0.35	GO:0016567	protein ubiquitination

0.67	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity
0.53	GO:0004674	protein serine/threonine kinase activity
0.44	GO:0032559	adenyl ribonucleotide binding
0.44	GO:0008144	drug binding
0.44	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0004842	ubiquitin-protein transferase activity
0.34	GO:0005515	protein binding

0.55	GO:0005730	nucleolus
0.48	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.67	EC:2.7.11.2	GO:0004740
0.35	KEGG:R03876	GO:0004842

sp|Q15121|PEA15_HUMAN
Astrocytic phosphoprotein PEA-15
Search

PEA15

0.97	Phosphoprotein enriched in astrocytes 15

0.81	GO:0000077	DNA damage checkpoint
0.74	GO:0042981	regulation of apoptotic process
0.70	GO:0046325	negative regulation of glucose import
0.63	GO:0043069	negative regulation of programmed cell death
0.63	GO:0043068	positive regulation of programmed cell death
0.61	GO:0009967	positive regulation of signal transduction
0.60	GO:0009968	negative regulation of signal transduction

0.57	GO:0005829	cytosol
0.52	GO:0005634	nucleus

sp|Q15124|PGM5_HUMAN
Phosphoglucomutase-like protein 5
Search

PGM5

0.80	Phosphoglucomutase 5

0.60	GO:0005975	carbohydrate metabolic process
0.46	GO:0006112	energy reserve metabolic process
0.45	GO:0030239	myofibril assembly
0.44	GO:0014706	striated muscle tissue development
0.43	GO:0044282	small molecule catabolic process
0.41	GO:1901575	organic substance catabolic process
0.38	GO:0009059	macromolecule biosynthetic process
0.37	GO:0044260	cellular macromolecule metabolic process
0.37	GO:0044249	cellular biosynthetic process
0.35	GO:0007155	cell adhesion

0.74	GO:0016868	intramolecular transferase activity, phosphotransferases
0.59	GO:0000287	magnesium ion binding
0.34	GO:0005509	calcium ion binding
0.33	GO:0005515	protein binding
0.33	GO:0005198	structural molecule activity

0.60	GO:0005914	spot adherens junction
0.58	GO:0043034	costamere
0.56	GO:0014704	intercalated disc
0.56	GO:0042383	sarcolemma
0.56	GO:0097517	contractile actin filament bundle
0.56	GO:0042641	actomyosin
0.55	GO:0030055	cell-substrate junction
0.55	GO:0030018	Z disc
0.54	GO:0016010	dystrophin-associated glycoprotein complex
0.51	GO:0009898	cytoplasmic side of plasma membrane

0.74

EC:5.4.2

GO:0016868

sp|Q15125|EBP_HUMAN
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase
Search

EBP

0.53	3-beta hydroxysteroid dehydrogenase

0.78	GO:0016125	sterol metabolic process
0.53	GO:1902653	secondary alcohol biosynthetic process
0.52	GO:0030097	hemopoiesis
0.52	GO:0006694	steroid biosynthetic process
0.35	GO:0001501	skeletal system development
0.34	GO:0006855	drug transmembrane transport
0.33	GO:0007165	signal transduction
0.31	GO:0055114	oxidation-reduction process

0.85	GO:0047750	cholestenol delta-isomerase activity
0.59	GO:0000247	C-8 sterol isomerase activity
0.58	GO:0004769	steroid delta-isomerase activity
0.34	GO:0015238	drug transmembrane transporter activity
0.34	GO:0004888	transmembrane signaling receptor activity
0.34	GO:0005515	protein binding
0.33	GO:0003723	RNA binding
0.32	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity

0.51	GO:0005635	nuclear envelope
0.49	GO:0005783	endoplasmic reticulum
0.38	GO:0031410	cytoplasmic vesicle
0.37	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.37	GO:0031984	organelle subcompartment
0.34	GO:0005887	integral component of plasma membrane

0.85

EC:5.3.3.5

GO:0047750

sp|Q15126|PMVK_HUMAN
Phosphomevalonate kinase
Search

PMVK

0.64	Phosphomevalonate kinase

0.85	GO:0006695	cholesterol biosynthetic process
0.69	GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway
0.59	GO:0070723	response to cholesterol
0.57	GO:0016310	phosphorylation
0.36	GO:0045540	regulation of cholesterol biosynthetic process
0.34	GO:0030154	cell differentiation
0.34	GO:0045892	negative regulation of transcription, DNA-templated
0.33	GO:0006605	protein targeting
0.33	GO:0071806	protein transmembrane transport

0.85	GO:0004631	phosphomevalonate kinase activity
0.52	GO:0032559	adenyl ribonucleotide binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0003714	transcription corepressor activity
0.33	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity

0.64	GO:0005777	peroxisome
0.49	GO:0005829	cytosol
0.37	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.85	EC:2.7.4.2	GO:0004631
0.85	KEGG:R03245	GO:0004631

sp|Q15131|CDK10_HUMAN
Cyclin-dependent kinase 10
Search

CDK10

0.95	Cell division protein kinase 10

0.63	GO:0006468	protein phosphorylation
0.57	GO:1902018	negative regulation of cilium assembly
0.54	GO:0018210	peptidyl-threonine modification
0.52	GO:0043410	positive regulation of MAPK cascade
0.51	GO:0032956	regulation of actin cytoskeleton organization
0.50	GO:0051726	regulation of cell cycle
0.43	GO:0043524	negative regulation of neuron apoptotic process
0.42	GO:0051301	cell division
0.41	GO:0022008	neurogenesis
0.41	GO:0016570	histone modification

0.66	GO:0004674	protein serine/threonine kinase activity
0.56	GO:0097472	cyclin-dependent protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0005515	protein binding
0.33	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.32	GO:0003676	nucleic acid binding

0.53	GO:0036064	ciliary basal body
0.45	GO:0016592	mediator complex
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.66

GO:0004674

sp|Q15139|KPCD1_HUMAN
Serine/threonine-protein kinase D1
Search

PRKD1

0.45	Serine/threonine-protein kinase

0.63	GO:0006468	protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.55	GO:0010837	regulation of keratinocyte proliferation
0.54	GO:0045669	positive regulation of osteoblast differentiation
0.54	GO:0042993	positive regulation of transcription factor import into nucleus
0.53	GO:0051279	regulation of release of sequestered calcium ion into cytosol
0.52	GO:0050829	defense response to Gram-negative bacterium
0.49	GO:0048193	Golgi vesicle transport
0.44	GO:0045765	regulation of angiogenesis
0.43	GO:1901490	regulation of lymphangiogenesis

0.84	GO:0004697	protein kinase C activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0032555	purine ribonucleotide binding
0.53	GO:0046872	metal ion binding
0.37	GO:0042802	identical protein binding
0.36	GO:0005080	protein kinase C binding

0.51	GO:0005802	trans-Golgi network
0.50	GO:0005829	cytosol
0.49	GO:0005911	cell-cell junction
0.49	GO:0005938	cell cortex
0.46	GO:0005634	nucleus
0.41	GO:0070013	intracellular organelle lumen
0.41	GO:0005886	plasma membrane
0.39	GO:0000421	autophagosome membrane
0.30	GO:0016021	integral component of membrane

0.84

EC:2.7.11.13

GO:0004697

sp|Q15147|PLCB4_HUMAN
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4
Search

PLCB4

0.53	Phosphoinositide phospholipase C

0.71	GO:0016042	lipid catabolic process
0.62	GO:0035556	intracellular signal transduction

0.80	GO:0004435	phosphatidylinositol phospholipase C activity
0.68	GO:0005509	calcium ion binding
0.63	GO:0004871	signal transducer activity
0.36	GO:0005515	protein binding

0.56	GO:0005790	smooth endoplasmic reticulum
0.54	GO:0014069	postsynaptic density
0.53	GO:0030425	dendrite
0.44	GO:0005634	nucleus

0.80	EC:3.1.4.11	GO:0004435
0.80	KEGG:R03435	GO:0004435

sp|Q15149|PLEC_HUMAN
Plectin
Search

PLEC

0.69

Plectin b

0.46	GO:0031581	hemidesmosome assembly
0.35	GO:0007519	skeletal muscle tissue development
0.35	GO:0007626	locomotory behavior
0.33	GO:0007565	female pregnancy
0.33	GO:0007584	response to nutrient
0.33	GO:0030855	epithelial cell differentiation
0.32	GO:0007010	cytoskeleton organization

0.73	GO:0003779	actin binding
0.46	GO:0030506	ankyrin binding
0.44	GO:0045296	cadherin binding
0.35	GO:0008307	structural constituent of muscle
0.33	GO:0047485	protein N-terminus binding
0.33	GO:0005200	structural constituent of cytoskeleton
0.32	GO:0003723	RNA binding
0.32	GO:0008017	microtubule binding
0.32	GO:0005509	calcium ion binding

0.69	GO:0005856	cytoskeleton
0.47	GO:0030056	hemidesmosome
0.46	GO:0005903	brush border
0.45	GO:0043292	contractile fiber
0.45	GO:0042383	sarcolemma
0.44	GO:0005925	focal adhesion
0.41	GO:0005829	cytosol
0.34	GO:0031012	extracellular matrix
0.34	GO:0016528	sarcoplasm
0.34	GO:0070062	extracellular exosome

sp|Q15154|PCM1_HUMAN
Pericentriolar material 1 protein
Search

PCM1

0.95	Pericentriolar material 1

0.85	GO:0034454	microtubule anchoring at centrosome
0.85	GO:0071539	protein localization to centrosome
0.79	GO:0060271	cilium assembly
0.58	GO:0022027	interkinetic nuclear migration
0.56	GO:0097150	neuronal stem cell population maintenance
0.55	GO:0035176	social behavior
0.55	GO:0007098	centrosome cycle
0.54	GO:0042073	intraciliary transport
0.54	GO:0031122	cytoplasmic microtubule organization
0.54	GO:0090316	positive regulation of intracellular protein transport

0.36

GO:0042802

identical protein binding

0.77	GO:0005813	centrosome
0.54	GO:0035869	ciliary transition zone
0.53	GO:0036064	ciliary basal body
0.53	GO:0005814	centriole
0.53	GO:0031965	nuclear membrane
0.52	GO:0045177	apical part of cell
0.48	GO:0005829	cytosol
0.43	GO:0043234	protein complex
0.38	GO:0097730	non-motile cilium
0.30	GO:0016021	integral component of membrane

sp|Q15155|NOMO1_HUMAN
Nodal modulator 1
Search

NOMO1

0.91	Nodal modulator 1

0.45	GO:1900176	negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry
0.37	GO:0031648	protein destabilization

0.69	GO:0030246	carbohydrate binding
0.33	GO:0005515	protein binding

0.41	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q15165|PON2_HUMAN
Serum paraoxonase/arylesterase 2
Search

PON2

0.89	Serum paraoxonase/arylesterase 2

0.45	GO:0019439	aromatic compound catabolic process
0.45	GO:0009636	response to toxic substance
0.42	GO:0016311	dephosphorylation
0.42	GO:0010875	positive regulation of cholesterol efflux
0.42	GO:0019372	lipoxygenase pathway
0.41	GO:0032929	negative regulation of superoxide anion generation
0.41	GO:0032411	positive regulation of transporter activity
0.41	GO:0051099	positive regulation of binding
0.41	GO:0008203	cholesterol metabolic process
0.41	GO:0046470	phosphatidylcholine metabolic process

0.85	GO:0004064	arylesterase activity
0.51	GO:0102007	acyl-L-homoserine-lactone lactonohydrolase activity
0.50	GO:0004063	aryldialkylphosphatase activity
0.47	GO:0042802	identical protein binding
0.40	GO:0046983	protein dimerization activity
0.40	GO:0018733	3,4-dihydrocoumarin hydrolase activity
0.40	GO:0046872	metal ion binding
0.40	GO:0047856	dihydrocoumarin hydrolase activity
0.39	GO:0005543	phospholipid binding
0.37	GO:0008035	high-density lipoprotein particle binding

0.61	GO:0005576	extracellular region
0.43	GO:1990777	lipoprotein particle
0.40	GO:0005764	lysosome
0.38	GO:0005886	plasma membrane
0.37	GO:0031982	vesicle
0.37	GO:0005634	nucleus
0.36	GO:0005739	mitochondrion
0.30	GO:0016021	integral component of membrane

0.85	EC:3.1.1.2	GO:0004064
0.40	KEGG:R03692	GO:0047856

sp|Q15166|PON3_HUMAN
Serum paraoxonase/lactonase 3
Search

0.89	Paraoxonase 3

0.66	GO:0032929	negative regulation of superoxide anion generation
0.61	GO:0019439	aromatic compound catabolic process
0.55	GO:0046395	carboxylic acid catabolic process
0.51	GO:0009636	response to toxic substance
0.49	GO:0010875	positive regulation of cholesterol efflux
0.47	GO:0032411	positive regulation of transporter activity
0.47	GO:0051099	positive regulation of binding
0.47	GO:0008203	cholesterol metabolic process
0.47	GO:0046470	phosphatidylcholine metabolic process
0.45	GO:0016311	dephosphorylation

0.85	GO:0004064	arylesterase activity
0.67	GO:0042802	identical protein binding
0.55	GO:0046983	protein dimerization activity
0.53	GO:0004063	aryldialkylphosphatase activity
0.44	GO:0005543	phospholipid binding
0.43	GO:0005509	calcium ion binding

0.63	GO:0005576	extracellular region
0.48	GO:1990777	lipoprotein particle
0.44	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.85

EC:3.1.1.2

GO:0004064

sp|Q15170|TCAL1_HUMAN
Transcription elongation factor A protein-like 1
Search

TCEAL1

0.97	Transcription elongation factor A like 1

0.56	GO:0006414	translational elongation
0.50	GO:0006357	regulation of transcription by RNA polymerase II
0.44	GO:0006351	transcription, DNA-templated
0.39	GO:0045892	negative regulation of transcription, DNA-templated

0.59	GO:0050699	WW domain binding
0.57	GO:0003746	translation elongation factor activity
0.37	GO:0003700	DNA binding transcription factor activity

0.62

GO:0005654

nucleoplasm

sp|Q15172|2A5A_HUMAN
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform
Search

PPP2R5A

0.60	Serine/threonine protein phosphatase 2A regulatory subunit

0.78	GO:0043666	regulation of phosphoprotein phosphatase activity
0.60	GO:0007165	signal transduction
0.59	GO:0090219	negative regulation of lipid kinase activity
0.57	GO:1903077	negative regulation of protein localization to plasma membrane
0.55	GO:0035307	positive regulation of protein dephosphorylation
0.49	GO:0006470	protein dephosphorylation

0.79	GO:0019888	protein phosphatase regulator activity
0.52	GO:0019900	kinase binding
0.49	GO:0004721	phosphoprotein phosphatase activity

0.80	GO:0000159	protein phosphatase type 2A complex
0.56	GO:0031430	M band
0.55	GO:0030018	Z disc
0.52	GO:0005813	centrosome
0.48	GO:0005829	cytosol
0.36	GO:0000775	chromosome, centromeric region
0.34	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.49

GO:0004721

sp|Q15173|2A5B_HUMAN
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform
Search

PPP2R5B

0.61	Serine/threonine protein phosphatase 2A regulatory subunit

0.79	GO:0043666	regulation of phosphoprotein phosphatase activity
0.61	GO:0007165	signal transduction
0.41	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway
0.40	GO:0070317	negative regulation of G0 to G1 transition
0.40	GO:0031952	regulation of protein autophosphorylation
0.40	GO:0071158	positive regulation of cell cycle arrest
0.39	GO:0010976	positive regulation of neuron projection development
0.39	GO:0050730	regulation of peptidyl-tyrosine phosphorylation
0.39	GO:0051091	positive regulation of DNA binding transcription factor activity
0.39	GO:0051173	positive regulation of nitrogen compound metabolic process

0.80	GO:0019888	protein phosphatase regulator activity
0.38	GO:0019900	kinase binding
0.37	GO:0004721	phosphoprotein phosphatase activity
0.37	GO:0019211	phosphatase activator activity

0.81	GO:0000159	protein phosphatase type 2A complex
0.37	GO:0005829	cytosol
0.37	GO:0031430	M band
0.37	GO:0030018	Z disc
0.36	GO:0005813	centrosome
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.37

GO:0004721

sp|Q15181|IPYR_HUMAN
Inorganic pyrophosphatase
Search

PPA1

0.46	Inorganic pyrophosphatase

0.55	GO:0006796	phosphate-containing compound metabolic process
0.36	GO:0046907	intracellular transport
0.36	GO:0071344	diphosphate metabolic process
0.36	GO:0016192	vesicle-mediated transport
0.36	GO:0034613	cellular protein localization
0.35	GO:0015031	protein transport
0.35	GO:1901303	negative regulation of cargo loading into COPII-coated vesicle
0.34	GO:0007186	G-protein coupled receptor signaling pathway
0.34	GO:0051668	localization within membrane
0.34	GO:0016050	vesicle organization

0.78	GO:0004427	inorganic diphosphatase activity
0.64	GO:0000287	magnesium ion binding
0.35	GO:0032550	purine ribonucleoside binding
0.35	GO:0019001	guanyl nucleotide binding
0.34	GO:0004930	G-protein coupled receptor activity
0.34	GO:0001653	peptide receptor activity
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.49	GO:0005737	cytoplasm
0.38	GO:0070062	extracellular exosome
0.36	GO:0012505	endomembrane system
0.34	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0012506	vesicle membrane
0.34	GO:0048475	coated membrane
0.33	GO:0097708	intracellular vesicle
0.33	GO:0098805	whole membrane
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0031984	organelle subcompartment

0.78	EC:3.6.1.1	GO:0004427
0.78	KEGG:R00004	GO:0004427

sp|Q15185|TEBP_HUMAN
Prostaglandin E synthase 3
Search

PTGES3

0.97	Prostaglandin E synthase 3

0.74	GO:0046457	prostanoid biosynthetic process
0.73	GO:0006693	prostaglandin metabolic process
0.73	GO:1905323	telomerase holoenzyme complex assembly
0.69	GO:0051973	positive regulation of telomerase activity
0.69	GO:0007004	telomere maintenance via telomerase
0.69	GO:0060430	lung saccule development
0.68	GO:0042921	glucocorticoid receptor signaling pathway
0.64	GO:0043588	skin development
0.61	GO:0008283	cell proliferation
0.59	GO:0005978	glycogen biosynthetic process

0.70	GO:0070182	DNA polymerase binding
0.62	GO:0050220	prostaglandin-E synthase activity
0.50	GO:0003720	telomerase activity
0.48	GO:0051879	Hsp90 protein binding
0.45	GO:0051082	unfolded protein binding
0.44	GO:0002039	p53 binding
0.41	GO:0033142	progesterone receptor binding
0.39	GO:0003896	DNA primase activity
0.35	GO:0046872	metal ion binding

0.59	GO:0005654	nucleoplasm
0.59	GO:0005829	cytosol
0.50	GO:0005697	telomerase holoenzyme complex
0.44	GO:0005884	actin filament
0.43	GO:0070062	extracellular exosome
0.43	GO:0043025	neuronal cell body
0.43	GO:0048471	perinuclear region of cytoplasm
0.42	GO:0043005	neuron projection
0.39	GO:0043234	protein complex
0.39	GO:0000781	chromosome, telomeric region

0.62	EC:5.3.99.3	GO:0050220
0.62	KEGG:R02265	GO:0050220

sp|Q15195|PLGA_HUMAN
Plasminogen-like protein A
Search

0.90	Plasminogen-like protein A

0.66

GO:0005576

extracellular region

sp|Q15198|PGFRL_HUMAN
Platelet-derived growth factor receptor-like protein
Search

PDGFRL

0.97	Platelet derived growth factor receptor like

0.48	GO:0035791	platelet-derived growth factor receptor-beta signaling pathway
0.42	GO:0007186	G-protein coupled receptor signaling pathway

0.65	GO:0042802	identical protein binding
0.49	GO:0005019	platelet-derived growth factor beta-receptor activity
0.48	GO:0004992	platelet activating factor receptor activity

0.53

GO:0005576

extracellular region

sp|Q15208|STK38_HUMAN
Serine/threonine-protein kinase 38
Search

STK38

0.95	Serine/threonine-protein kinase 38

0.63	GO:0006468	protein phosphorylation
0.57	GO:0043407	negative regulation of MAP kinase activity
0.49	GO:0018209	peptidyl-serine modification
0.49	GO:0035556	intracellular signal transduction
0.39	GO:0051128	regulation of cellular component organization

0.69	GO:0004674	protein serine/threonine kinase activity
0.59	GO:0031435	mitogen-activated protein kinase kinase kinase binding
0.55	GO:0045296	cadherin binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0000287	magnesium ion binding
0.34	GO:0003779	actin binding

0.52	GO:0005829	cytosol
0.46	GO:0005634	nucleus
0.42	GO:0015629	actin cytoskeleton
0.30	GO:0016020	membrane

0.69

GO:0004674

sp|Q15223|NECT1_HUMAN
Nectin-1
Search

NECTIN1

0.97	Nectin cell adhesion molecule 1

0.82	GO:0051963	regulation of synapse assembly
0.71	GO:0007155	cell adhesion
0.66	GO:0051806	entry into cell of other organism involved in symbiotic interaction
0.66	GO:0044409	entry into host
0.64	GO:0019058	viral life cycle
0.60	GO:1902414	protein localization to cell junction
0.59	GO:0002934	desmosome organization
0.59	GO:0002089	lens morphogenesis in camera-type eye
0.59	GO:0070166	enamel mineralization
0.56	GO:0060041	retina development in camera-type eye

0.79	GO:0050839	cell adhesion molecule binding
0.74	GO:0042803	protein homodimerization activity
0.73	GO:0046982	protein heterodimerization activity
0.48	GO:0004872	receptor activity
0.45	GO:0005102	receptor binding
0.41	GO:0046790	virion binding
0.37	GO:0030246	carbohydrate binding
0.36	GO:0001618	virus receptor activity
0.34	GO:0004871	signal transducer activity

0.78	GO:0005912	adherens junction
0.74	GO:0045202	synapse
0.57	GO:0044291	cell-cell contact zone
0.55	GO:0043296	apical junction complex
0.43	GO:0005887	integral component of plasma membrane
0.41	GO:0032584	growth cone membrane
0.40	GO:0016342	catenin complex
0.39	GO:0030424	axon
0.37	GO:0098590	plasma membrane region
0.35	GO:0043231	intracellular membrane-bounded organelle

sp|Q15233|NONO_HUMAN
Non-POU domain-containing octamer-binding protein
Search

NONO

0.97	Non-POU domain containing octamer binding

0.56	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
0.52	GO:0042752	regulation of circadian rhythm
0.52	GO:0002218	activation of innate immune response
0.47	GO:0045892	negative regulation of transcription, DNA-templated
0.45	GO:0000398	mRNA splicing, via spliceosome
0.42	GO:0071599	otic vesicle development
0.41	GO:0061053	somite development
0.41	GO:0007623	circadian rhythm
0.40	GO:0007417	central nervous system development
0.38	GO:0045087	innate immune response

0.59	GO:0003723	RNA binding
0.53	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.52	GO:0001047	core promoter binding
0.49	GO:0003682	chromatin binding
0.48	GO:0042802	identical protein binding
0.35	GO:0004402	histone acetyltransferase activity
0.34	GO:0003713	transcription coactivator activity
0.33	GO:0008270	zinc ion binding
0.32	GO:0003735	structural constituent of ribosome
0.32	GO:0016787	hydrolase activity

0.56	GO:0042382	paraspeckles
0.53	GO:0016363	nuclear matrix
0.49	GO:0090575	RNA polymerase II transcription factor complex
0.39	GO:0016607	nuclear speck
0.37	GO:0005730	nucleolus
0.34	GO:0000123	histone acetyltransferase complex
0.33	GO:1990904	ribonucleoprotein complex
0.33	GO:0019013	viral nucleocapsid
0.32	GO:0044444	cytoplasmic part
0.30	GO:0016021	integral component of membrane

0.35

GO:0004402

sp|Q15238|PSG5_HUMAN
Pregnancy-specific beta-1-glycoprotein 5
Search

0.87	Pregnancy-specific beta-1-glycoprotein 5

0.71	GO:0007565	female pregnancy
0.48	GO:0016477	cell migration
0.46	GO:0043317	regulation of cytotoxic T cell degranulation
0.45	GO:0002859	negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
0.45	GO:0001915	negative regulation of T cell mediated cytotoxicity
0.45	GO:0043312	neutrophil degranulation
0.44	GO:0030334	regulation of cell migration
0.44	GO:0043301	negative regulation of leukocyte degranulation
0.44	GO:0050860	negative regulation of T cell receptor signaling pathway
0.43	GO:0090505	epiboly involved in wound healing

0.44	GO:0031005	filamin binding
0.43	GO:1990782	protein tyrosine kinase binding
0.42	GO:0019903	protein phosphatase binding
0.42	GO:0042803	protein homodimerization activity
0.40	GO:0003779	actin binding
0.38	GO:0015125	bile acid transmembrane transporter activity
0.38	GO:0034235	GPI anchor binding
0.37	GO:0005516	calmodulin binding

0.49	GO:0005576	extracellular region
0.44	GO:0030667	secretory granule membrane
0.43	GO:0042101	T cell receptor complex
0.42	GO:0042581	specific granule
0.42	GO:0009986	cell surface
0.41	GO:0031225	anchored component of membrane
0.41	GO:0070820	tertiary granule
0.41	GO:0005766	primary lysosome
0.41	GO:0005911	cell-cell junction
0.40	GO:0005765	lysosomal membrane

sp|Q15256|PTPRR_HUMAN
Receptor-type tyrosine-protein phosphatase R
Search

PTPRR

0.96	Receptor-type tyrosine-protein phosphatase R

0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.61	GO:0038128	ERBB2 signaling pathway
0.58	GO:0010633	negative regulation of epithelial cell migration
0.57	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.55	GO:0001701	in utero embryonic development
0.39	GO:1903385	regulation of homophilic cell adhesion
0.35	GO:0030182	neuron differentiation

0.75	GO:0004725	protein tyrosine phosphatase activity
0.54	GO:0019901	protein kinase binding
0.36	GO:0019198	transmembrane receptor protein phosphatase activity
0.33	GO:0001784	phosphotyrosine residue binding

0.52	GO:0030054	cell junction
0.49	GO:0005829	cytosol
0.43	GO:0005886	plasma membrane
0.36	GO:0005615	extracellular space
0.35	GO:0048471	perinuclear region of cytoplasm
0.30	GO:0016021	integral component of membrane

0.75

GO:0004725

sp|Q15257|PTPA_HUMAN
Serine/threonine-protein phosphatase 2A activator
Search

PTPA

0.65	Serine/threonine-protein phosphatase 2A activator

0.73	GO:0043085	positive regulation of catalytic activity
0.72	GO:0000413	protein peptidyl-prolyl isomerization
0.55	GO:0035307	positive regulation of protein dephosphorylation
0.53	GO:0032515	negative regulation of phosphoprotein phosphatase activity
0.51	GO:0043065	positive regulation of apoptotic process
0.48	GO:0030472	mitotic spindle organization in nucleus

0.85	GO:0019211	phosphatase activator activity
0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.56	GO:0051721	protein phosphatase 2A binding
0.54	GO:0019888	protein phosphatase regulator activity
0.50	GO:0042803	protein homodimerization activity
0.49	GO:0005102	receptor binding
0.44	GO:0016887	ATPase activity
0.41	GO:0032559	adenyl ribonucleotide binding
0.41	GO:0008144	drug binding
0.41	GO:0035639	purine ribonucleoside triphosphate binding

0.54	GO:0000159	protein phosphatase type 2A complex
0.52	GO:0034704	calcium channel complex
0.49	GO:0005737	cytoplasm
0.48	GO:0005654	nucleoplasm
0.36	GO:0070062	extracellular exosome

0.72

GO:0003755

sp|Q15262|PTPRK_HUMAN
Receptor-type tyrosine-protein phosphatase kappa
Search

PTPRK

0.85	Mutant receptor type protein tyrosine phosphatase K

0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.65	GO:0010839	negative regulation of keratinocyte proliferation
0.65	GO:0048041	focal adhesion assembly
0.64	GO:0034394	protein localization to cell surface
0.62	GO:0034644	cellular response to UV
0.61	GO:0007179	transforming growth factor beta receptor signaling pathway
0.61	GO:0030336	negative regulation of cell migration
0.58	GO:0016477	cell migration
0.57	GO:0045786	negative regulation of cell cycle
0.57	GO:0034614	cellular response to reactive oxygen species

0.74	GO:0004725	protein tyrosine phosphatase activity
0.66	GO:0045295	gamma-catenin binding
0.61	GO:0008013	beta-catenin binding
0.58	GO:0019901	protein kinase binding

0.62	GO:0001750	photoreceptor outer segment
0.62	GO:0031256	leading edge membrane
0.60	GO:0043025	neuronal cell body
0.60	GO:0030425	dendrite
0.59	GO:0030424	axon
0.57	GO:0005911	cell-cell junction
0.57	GO:0009986	cell surface
0.45	GO:0043227	membrane-bounded organelle
0.43	GO:0043229	intracellular organelle
0.30	GO:0016021	integral component of membrane

0.74

GO:0004725

sp|Q15269|PWP2_HUMAN
Periodic tryptophan protein 2 homolog
Search

PWP2

0.83	Periodic tryptophan protein 2

0.83	GO:0000028	ribosomal small subunit assembly
0.71	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.63	GO:0055123	digestive system development
0.37	GO:0000920	cell separation after cytokinesis
0.37	GO:0000479	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.37	GO:0030010	establishment of cell polarity
0.36	GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.36	GO:0000967	rRNA 5'-end processing

0.72

GO:0030515

snoRNA binding

0.76	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome
0.69	GO:0032040	small-subunit processome
0.39	GO:0005654	nucleoplasm
0.33	GO:0005737	cytoplasm

sp|Q15270|NKX11_HUMAN
NK1 transcription factor-related protein 1
Search

NKX1-1

0.90	NK1 transcription factor-related protein 1

0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression
0.50	GO:0010906	regulation of glucose metabolic process
0.49	GO:0043467	regulation of generation of precursor metabolites and energy
0.46	GO:0050877	nervous system process
0.43	GO:0006629	lipid metabolic process
0.35	GO:0007275	multicellular organism development

0.64	GO:0043565	sequence-specific DNA binding
0.33	GO:0004000	adenosine deaminase activity
0.33	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.30	GO:0044425	membrane part

0.33

EC:3.5.4.4

GO:0004000

sp|Q15274|NADC_HUMAN
Nicotinate-nucleotide pyrophosphorylase [carboxylating]
Search

QPRT

0.58	Nicotinate-nucleotide pyrophosphorylase

0.72	GO:0009435	NAD biosynthetic process
0.48	GO:0034213	quinolinate catabolic process
0.37	GO:0051259	protein oligomerization

0.76	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity
0.38	GO:0042803	protein homodimerization activity
0.33	GO:1901265	nucleoside phosphate binding
0.32	GO:0036094	small molecule binding

0.37	GO:0070062	extracellular exosome
0.35	GO:0005737	cytoplasm

0.76	EC:2.4.2.19	GO:0004514
0.76	KEGG:R03348	GO:0004514

sp|Q15276|RABE1_HUMAN
Rab GTPase-binding effector protein 1
Search

RABEP1

0.92	Rab GTPase-binding effector protein 1

0.76	GO:0043547	positive regulation of GTPase activity
0.75	GO:0010469	regulation of receptor activity
0.71	GO:0006897	endocytosis
0.42	GO:0060271	cilium assembly
0.32	GO:0006915	apoptotic process
0.32	GO:0015031	protein transport
0.32	GO:0010976	positive regulation of neuron projection development
0.31	GO:0061025	membrane fusion

0.78	GO:0008083	growth factor activity
0.76	GO:0005096	GTPase activator activity
0.44	GO:0019904	protein domain specific binding
0.43	GO:0042803	protein homodimerization activity

0.76	GO:0005768	endosome
0.45	GO:0030139	endocytic vesicle
0.39	GO:0043234	protein complex
0.38	GO:0043231	intracellular membrane-bounded organelle
0.31	GO:0044433	cytoplasmic vesicle part
0.31	GO:0005615	extracellular space
0.31	GO:0098805	whole membrane
0.31	GO:0098588	bounding membrane of organelle
0.30	GO:0016021	integral component of membrane

sp|Q15283|RASA2_HUMAN
Ras GTPase-activating protein 2
Search

RASA2

0.97	Ras GTPase-activating protein 2

0.77	GO:0046580	negative regulation of Ras protein signal transduction
0.73	GO:0043547	positive regulation of GTPase activity
0.61	GO:0035556	intracellular signal transduction
0.44	GO:0051209	release of sequestered calcium ion into cytosol
0.37	GO:0043363	nucleate erythrocyte differentiation
0.37	GO:0002574	thrombocyte differentiation
0.34	GO:0034605	cellular response to heat
0.34	GO:0023014	signal transduction by protein phosphorylation

0.74	GO:0005096	GTPase activator activity
0.64	GO:0005543	phospholipid binding
0.44	GO:0015278	calcium-release channel activity
0.34	GO:0046872	metal ion binding

0.52	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane
0.44	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|Q15286|RAB35_HUMAN
Ras-related protein Rab-35
Search

RAB35

0.96	RAB35 member RAS oncogene family

0.55	GO:0048227	plasma membrane to endosome transport
0.54	GO:0036010	protein localization to endosome
0.53	GO:0016197	endosomal transport
0.51	GO:0000281	mitotic cytokinesis
0.49	GO:0031175	neuron projection development
0.49	GO:0019882	antigen processing and presentation
0.39	GO:1990090	cellular response to nerve growth factor stimulus
0.35	GO:0015031	protein transport
0.34	GO:0033674	positive regulation of kinase activity
0.34	GO:0045859	regulation of protein kinase activity

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.36	GO:0071532	ankyrin repeat binding
0.36	GO:0032794	GTPase activating protein binding
0.34	GO:0019887	protein kinase regulator activity
0.34	GO:0019901	protein kinase binding

0.52	GO:0045171	intercellular bridge
0.52	GO:0045334	clathrin-coated endocytic vesicle
0.51	GO:0031253	cell projection membrane
0.50	GO:0005905	clathrin-coated pit
0.47	GO:0010008	endosome membrane
0.42	GO:0005739	mitochondrion
0.40	GO:0098993	anchored component of synaptic vesicle membrane
0.38	GO:0042470	melanosome
0.37	GO:0055037	recycling endosome
0.36	GO:0070062	extracellular exosome

sp|Q15287|RNPS1_HUMAN
RNA-binding protein with serine-rich domain 1
Search

RNPS1

0.69	RNA-binding protein with serine-rich domain 1-B

0.55	GO:0048025	negative regulation of mRNA splicing, via spliceosome
0.53	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.52	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.51	GO:0043065	positive regulation of apoptotic process
0.42	GO:0008380	RNA splicing
0.41	GO:0006397	mRNA processing
0.35	GO:0006369	termination of RNA polymerase II transcription
0.35	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.34	GO:0031123	RNA 3'-end processing
0.34	GO:0051028	mRNA transport

0.57	GO:0003723	RNA binding
0.34	GO:0005515	protein binding

0.57	GO:0061574	ASAP complex
0.50	GO:0005654	nucleoplasm
0.39	GO:0005737	cytoplasm
0.35	GO:0035145	exon-exon junction complex

sp|Q15291|RBBP5_HUMAN
Retinoblastoma-binding protein 5
Search

RBBP5

0.93	RB binding protein 5, histone lysine methyltransferase complex subunit

0.77	GO:0043627	response to estrogen
0.74	GO:0051568	histone H3-K4 methylation
0.59	GO:0006974	cellular response to DNA damage stimulus

0.76	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.76	GO:0140034	methylation-dependent protein binding
0.72	GO:0042393	histone binding
0.69	GO:0044212	transcription regulatory region DNA binding

0.81	GO:0048188	Set1C/COMPASS complex
0.77	GO:0044666	MLL3/4 complex
0.74	GO:0071339	MLL1 complex
0.66	GO:0005730	nucleolus
0.30	GO:0031224	intrinsic component of membrane

sp|Q15293|RCN1_HUMAN
Reticulocalbin-1
Search

RCN1

0.97	Reticulocalbin 1, EF-hand calcium binding domain

0.52	GO:0043010	camera-type eye development
0.50	GO:0001701	in utero embryonic development
0.35	GO:0043687	post-translational protein modification

0.70	GO:0005509	calcium ion binding
0.33	GO:0005515	protein binding

0.48	GO:0005783	endoplasmic reticulum
0.36	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|Q15303|ERBB4_HUMAN
Receptor tyrosine-protein kinase erbB-4
Search

ERBB4

0.65	Receptor protein-tyrosine kinase

0.77	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.62	GO:0023014	signal transduction by protein phosphorylation
0.59	GO:0035556	intracellular signal transduction
0.57	GO:0061026	cardiac muscle tissue regeneration
0.56	GO:2000366	positive regulation of STAT protein import into nucleus
0.56	GO:2001223	negative regulation of neuron migration
0.56	GO:0043653	mitochondrial fragmentation involved in apoptotic process
0.56	GO:0021889	olfactory bulb interneuron differentiation
0.55	GO:0021551	central nervous system morphogenesis

0.81	GO:0004716	signal transducer, downstream of receptor, with protein tyrosine kinase activity
0.79	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0005154	epidermal growth factor receptor binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0044212	transcription regulatory region DNA binding
0.49	GO:0042803	protein homodimerization activity
0.36	GO:0038132	neuregulin binding

0.52	GO:0016323	basolateral plasma membrane
0.50	GO:0043235	receptor complex
0.43	GO:0005622	intracellular
0.41	GO:0043227	membrane-bounded organelle
0.35	GO:0005901	caveola
0.35	GO:0014069	postsynaptic density
0.34	GO:0031974	membrane-enclosed lumen
0.34	GO:0005576	extracellular region
0.33	GO:0044422	organelle part
0.30	GO:0016021	integral component of membrane

0.81	EC:2.7.10	GO:0004716
0.36	KEGG:R04545	GO:0046934

sp|Q15306|IRF4_HUMAN
Interferon regulatory factor 4
Search

IRF4

0.86	Interferon regulatory factor

0.62	GO:0045368	positive regulation of interleukin-13 biosynthetic process
0.62	GO:0045404	positive regulation of interleukin-4 biosynthetic process
0.61	GO:0045082	positive regulation of interleukin-10 biosynthetic process
0.60	GO:0045086	positive regulation of interleukin-2 biosynthetic process
0.59	GO:0072540	T-helper 17 cell lineage commitment
0.57	GO:0043011	myeloid dendritic cell differentiation
0.57	GO:0042832	defense response to protozoan
0.57	GO:0006351	transcription, DNA-templated
0.57	GO:0034122	negative regulation of toll-like receptor signaling pathway
0.56	GO:2001141	regulation of RNA biosynthetic process

0.75	GO:0044212	transcription regulatory region DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.53	GO:0016279	protein-lysine N-methyltransferase activity
0.52	GO:1990837	sequence-specific double-stranded DNA binding
0.35	GO:0005515	protein binding
0.32	GO:0003735	structural constituent of ribosome

0.60	GO:0005634	nucleus
0.51	GO:0000785	chromatin
0.50	GO:0044815	DNA packaging complex
0.49	GO:0032993	protein-DNA complex
0.48	GO:0070013	intracellular organelle lumen
0.34	GO:0005829	cytosol
0.32	GO:0005840	ribosome
0.30	GO:0016020	membrane

0.53

GO:0016279

sp|Q15311|RBP1_HUMAN
RalA-binding protein 1
Search

RALBP1

0.92	RalA-binding protein 1-A

0.61	GO:0007165	signal transduction
0.52	GO:0043547	positive regulation of GTPase activity
0.51	GO:1900753	doxorubicin transport
0.48	GO:0006855	drug transmembrane transport
0.43	GO:0006897	endocytosis
0.36	GO:0001702	gastrulation with mouth forming second
0.36	GO:0007010	cytoskeleton organization
0.35	GO:1903378	positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
0.35	GO:0030029	actin filament-based process
0.35	GO:0048662	negative regulation of smooth muscle cell proliferation

0.58	GO:0017160	Ral GTPase binding
0.54	GO:0048365	Rac GTPase binding
0.52	GO:0005096	GTPase activator activity
0.47	GO:0015238	drug transmembrane transporter activity
0.45	GO:0042626	ATPase activity, coupled to transmembrane movement of substances

0.37	GO:0005622	intracellular
0.34	GO:0043005	neuron projection
0.33	GO:0005886	plasma membrane
0.33	GO:0043228	non-membrane-bounded organelle
0.33	GO:0044422	organelle part

sp|Q15319|PO4F3_HUMAN
POU domain, class 4, transcription factor 3
Search

POU4F3

0.54	POU domain, class 4, transcription factor 3

0.73	GO:0007605	sensory perception of sound
0.70	GO:0007423	sensory organ development
0.64	GO:0031290	retinal ganglion cell axon guidance
0.63	GO:0050885	neuromuscular process controlling balance
0.63	GO:0048675	axon extension
0.58	GO:0021562	vestibulocochlear nerve development
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0009888	tissue development

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.58	GO:0001012	RNA polymerase II regulatory region DNA binding
0.54	GO:0003690	double-stranded DNA binding
0.51	GO:1990841	promoter-specific chromatin binding
0.49	GO:0003714	transcription corepressor activity
0.36	GO:0003713	transcription coactivator activity
0.34	GO:0005515	protein binding
0.33	GO:0003723	RNA binding

0.61	GO:0005634	nucleus
0.52	GO:0070013	intracellular organelle lumen
0.46	GO:0044446	intracellular organelle part
0.41	GO:0005737	cytoplasm
0.34	GO:0005667	transcription factor complex
0.33	GO:0005886	plasma membrane

sp|Q15323|K1H1_HUMAN
Keratin, type I cuticular Ha1
Search

0.96	Hair acidic keratin 1

0.42	GO:0042633	hair cycle
0.41	GO:0007568	aging
0.40	GO:0070268	cornification
0.36	GO:0045616	regulation of keratinocyte differentiation
0.34	GO:0007010	cytoskeleton organization
0.33	GO:0009653	anatomical structure morphogenesis

0.62	GO:0005198	structural molecule activity
0.35	GO:0005515	protein binding

0.79	GO:0005882	intermediate filament
0.40	GO:0070062	extracellular exosome
0.37	GO:0005829	cytosol

sp|Q15326|ZMY11_HUMAN
Zinc finger MYND domain-containing protein 11
Search

ZMYND11

0.92	Zinc finger MYND domain-containing protein 11

0.55	GO:0046329	negative regulation of JNK cascade
0.54	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling
0.54	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway
0.50	GO:0051607	defense response to virus
0.44	GO:1903507	negative regulation of nucleic acid-templated transcription
0.44	GO:0006357	regulation of transcription by RNA polymerase II
0.42	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
0.41	GO:0010629	negative regulation of gene expression
0.40	GO:0032784	regulation of DNA-templated transcription, elongation
0.35	GO:0016569	covalent chromatin modification

0.53	GO:0042393	histone binding
0.53	GO:0140034	methylation-dependent protein binding
0.51	GO:0046872	metal ion binding
0.50	GO:0003690	double-stranded DNA binding
0.46	GO:0003712	transcription cofactor activity
0.44	GO:0001012	RNA polymerase II regulatory region DNA binding
0.44	GO:0003682	chromatin binding
0.41	GO:0043565	sequence-specific DNA binding

0.47	GO:0005654	nucleoplasm
0.35	GO:0005694	chromosome
0.30	GO:0031224	intrinsic component of membrane

sp|Q15327|ANKR1_HUMAN
Ankyrin repeat domain-containing protein 1
Search

ANKRD1

0.97	Ankyrin repeat domain-containing protein 1

0.84	GO:0035914	skeletal muscle cell differentiation
0.82	GO:1901796	regulation of signal transduction by p53 class mediator
0.78	GO:0035994	response to muscle stretch
0.76	GO:0071260	cellular response to mechanical stimulus
0.75	GO:2000279	negative regulation of DNA biosynthetic process
0.75	GO:0055008	cardiac muscle tissue morphogenesis
0.75	GO:0071347	cellular response to interleukin-1
0.74	GO:2001022	positive regulation of response to DNA damage stimulus
0.73	GO:0071356	cellular response to tumor necrosis factor
0.73	GO:0071222	cellular response to lipopolysaccharide

0.86	GO:0031432	titin binding
0.82	GO:0001085	RNA polymerase II transcription factor binding
0.78	GO:0070412	R-SMAD binding
0.75	GO:0001105	RNA polymerase II transcription coactivator activity
0.75	GO:0002039	p53 binding
0.74	GO:0042826	histone deacetylase binding
0.71	GO:0003714	transcription corepressor activity
0.58	GO:0043422	protein kinase B binding
0.51	GO:0003682	chromatin binding
0.50	GO:0003677	DNA binding

0.81	GO:0031674	I band
0.73	GO:0001650	fibrillar center
0.66	GO:0005829	cytosol
0.66	GO:0005667	transcription factor complex
0.55	GO:0000791	euchromatin
0.55	GO:0016605	PML body
0.37	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0015629	actin cytoskeleton
0.30	GO:0016020	membrane

sp|Q15329|E2F5_HUMAN
Transcription factor E2F5
Search

E2F5

0.86	E2F transcription factor 5

0.63	GO:0009887	animal organ morphogenesis
0.62	GO:0051726	regulation of cell cycle
0.60	GO:0000278	mitotic cell cycle
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.52	GO:0006884	cell volume homeostasis
0.52	GO:0044843	cell cycle G1/S phase transition
0.51	GO:0002064	epithelial cell development

0.68	GO:0046983	protein dimerization activity
0.61	GO:0003700	DNA binding transcription factor activity
0.61	GO:0008134	transcription factor binding
0.55	GO:0003677	DNA binding
0.53	GO:1990841	promoter-specific chromatin binding
0.49	GO:0019904	protein domain specific binding
0.49	GO:0001067	regulatory region nucleic acid binding

0.75	GO:0005667	transcription factor complex
0.62	GO:0001650	fibrillar center
0.48	GO:0000790	nuclear chromatin
0.46	GO:0005654	nucleoplasm
0.41	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q15334|L2GL1_HUMAN
Lethal(2) giant larvae protein homolog 1
Search

LLGL1

0.95	Lethal giant larvae

0.69	GO:0030866	cortical actin cytoskeleton organization
0.61	GO:0017157	regulation of exocytosis
0.59	GO:0050708	regulation of protein secretion
0.59	GO:0006461	protein complex assembly
0.59	GO:0048919	posterior lateral line neuromast development
0.57	GO:0043547	positive regulation of GTPase activity
0.52	GO:0003407	neural retina development
0.51	GO:0008593	regulation of Notch signaling pathway
0.49	GO:0032878	regulation of establishment or maintenance of cell polarity
0.47	GO:0120036	plasma membrane bounded cell projection organization

0.66	GO:0019901	protein kinase binding
0.62	GO:0019905	syntaxin binding
0.60	GO:0017137	Rab GTPase binding
0.57	GO:0005096	GTPase activator activity
0.53	GO:0030165	PDZ domain binding
0.37	GO:0003777	microtubule motor activity
0.37	GO:0008017	microtubule binding
0.37	GO:0003779	actin binding
0.35	GO:0005198	structural molecule activity
0.34	GO:0032559	adenyl ribonucleotide binding

0.68	GO:0030864	cortical actin cytoskeleton
0.53	GO:0016323	basolateral plasma membrane
0.46	GO:0032588	trans-Golgi network membrane
0.45	GO:0005829	cytosol
0.45	GO:0000137	Golgi cis cisterna
0.45	GO:0031901	early endosome membrane
0.44	GO:0030424	axon
0.42	GO:0035748	myelin sheath abaxonal region
0.37	GO:0016459	myosin complex

sp|Q15345|LRC41_HUMAN
Leucine-rich repeat-containing protein 41
Search

LRRC41

0.97	Leucine-rich repeat-containing protein 41

0.46	GO:0016567	protein ubiquitination
0.40	GO:0043687	post-translational protein modification

0.74

GO:0042803

protein homodimerization activity

0.60	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q15349|KS6A2_HUMAN
Ribosomal protein S6 kinase alpha-2
Search

RPS6KA2

0.74	Ribosomal protein S6 kinase, polypeptide 2

0.62	GO:0006468	protein phosphorylation
0.61	GO:0035556	intracellular signal transduction
0.44	GO:0010659	cardiac muscle cell apoptotic process
0.44	GO:0002035	brain renin-angiotensin system
0.43	GO:0001556	oocyte maturation
0.42	GO:0045835	negative regulation of meiotic nuclear division
0.42	GO:0071322	cellular response to carbohydrate stimulus
0.42	GO:0070613	regulation of protein processing
0.42	GO:0060047	heart contraction
0.41	GO:0018209	peptidyl-serine modification

0.69	GO:0004674	protein serine/threonine kinase activity
0.63	GO:0000287	magnesium ion binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0004712	protein serine/threonine/tyrosine kinase activity
0.35	GO:0005515	protein binding
0.35	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.33	GO:0004713	protein tyrosine kinase activity

0.44	GO:0005622	intracellular
0.38	GO:0043227	membrane-bounded organelle
0.37	GO:0043228	non-membrane-bounded organelle
0.37	GO:0044422	organelle part
0.35	GO:0031974	membrane-enclosed lumen
0.35	GO:1990904	ribonucleoprotein complex
0.32	GO:0031975	envelope
0.30	GO:0016020	membrane

0.69

GO:0004674

sp|Q15361|TTF1_HUMAN
Transcription termination factor 1
Search

TTF1

0.91	Transcription termination factor 1

0.48	GO:0030154	cell differentiation
0.48	GO:0006363	termination of RNA polymerase I transcription
0.48	GO:0006357	regulation of transcription by RNA polymerase II
0.47	GO:0006361	transcription initiation from RNA polymerase I promoter
0.45	GO:0006338	chromatin remodeling
0.40	GO:0000183	chromatin silencing at rDNA
0.39	GO:0008156	negative regulation of DNA replication
0.30	GO:1901564	organonitrogen compound metabolic process

0.54	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting
0.52	GO:0003677	DNA binding
0.50	GO:0001067	regulatory region nucleic acid binding
0.49	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.45	GO:0003682	chromatin binding
0.36	GO:0005515	protein binding

0.57	GO:0005730	nucleolus
0.53	GO:0005829	cytosol
0.45	GO:0005886	plasma membrane
0.37	GO:0005654	nucleoplasm

sp|Q15363|TMED2_HUMAN
Transmembrane emp24 domain-containing protein 2
Search

TMED2

0.86	Transmembrane emp24 domain trafficking protein 2

0.52	GO:0032525	somite rostral/caudal axis specification
0.51	GO:0034260	negative regulation of GTPase activity
0.51	GO:0036342	post-anal tail morphogenesis
0.50	GO:0001947	heart looping
0.50	GO:0001843	neural tube closure
0.50	GO:0035264	multicellular organism growth
0.50	GO:0072659	protein localization to plasma membrane
0.49	GO:0007030	Golgi organization
0.48	GO:0060716	labyrinthine layer blood vessel development
0.48	GO:0001893	maternal placenta development

0.36	GO:0004386	helicase activity
0.34	GO:0005515	protein binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0003676	nucleic acid binding
0.33	GO:0008168	methyltransferase activity

0.50	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.45	GO:0005794	Golgi apparatus
0.45	GO:0005783	endoplasmic reticulum
0.41	GO:0042589	zymogen granule membrane
0.40	GO:0030137	COPI-coated vesicle
0.38	GO:0030660	Golgi-associated vesicle membrane
0.38	GO:0030662	coated vesicle membrane
0.37	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0031984	organelle subcompartment
0.34	GO:0030134	COPII-coated ER to Golgi transport vesicle

0.33

GO:0008168

sp|Q15365|PCBP1_HUMAN
Poly(rC)-binding protein 1
Search

PCBP1

0.96	poly(RC)-binding protein 1

0.61	GO:0045944	positive regulation of transcription by RNA polymerase II
0.59	GO:0039694	viral RNA genome replication
0.39	GO:0006397	mRNA processing
0.38	GO:0045727	positive regulation of translation
0.38	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile

0.68	GO:0098847	sequence-specific single stranded DNA binding
0.67	GO:0045296	cadherin binding
0.63	GO:0003729	mRNA binding
0.60	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.40	GO:0008494	translation activator activity

0.66	GO:0016607	nuclear speck
0.65	GO:0036464	cytoplasmic ribonucleoprotein granule
0.57	GO:0005829	cytosol
0.38	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

sp|Q15366|PCBP2_HUMAN
Poly(rC)-binding protein 2
Search

PCBP2

0.91	Poly(rC)-binding protein 2

0.48	GO:0075522	IRES-dependent viral translational initiation
0.47	GO:0050687	negative regulation of defense response to virus
0.44	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.42	GO:0039694	viral RNA genome replication
0.40	GO:0045087	innate immune response
0.40	GO:0051607	defense response to virus
0.39	GO:0032480	negative regulation of type I interferon production
0.37	GO:0000398	mRNA splicing, via spliceosome
0.32	GO:0006468	protein phosphorylation

0.59	GO:0003723	RNA binding
0.45	GO:0031625	ubiquitin protein ligase binding
0.44	GO:1990829	C-rich single-stranded DNA binding
0.32	GO:0004672	protein kinase activity
0.31	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.41	GO:0005654	nucleoplasm
0.41	GO:0005925	focal adhesion
0.41	GO:0070062	extracellular exosome
0.41	GO:0005829	cytosol
0.37	GO:1990904	ribonucleoprotein complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q15369|ELOC_HUMAN
Elongin-C
Search

ELOC

0.92	Transcription elongation factor B

0.73	GO:0006511	ubiquitin-dependent protein catabolic process
0.60	GO:0006414	translational elongation
0.45	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter
0.43	GO:0016567	protein ubiquitination
0.35	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia
0.34	GO:0006351	transcription, DNA-templated
0.34	GO:0043687	post-translational protein modification
0.33	GO:0016032	viral process

0.61	GO:0003746	translation elongation factor activity
0.43	GO:0004842	ubiquitin-protein transferase activity
0.35	GO:0005515	protein binding
0.33	GO:0044877	macromolecular complex binding
0.33	GO:0016874	ligase activity

0.47	GO:0070449	elongin complex
0.35	GO:0030891	VCB complex
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.33	EC:6	GO:0016874
0.43	KEGG:R03876	GO:0004842

sp|Q15370|ELOB_HUMAN
Elongin-B
Search

0.94	Transcription elongation factor B

0.61	GO:0006414	translational elongation
0.37	GO:0016567	protein ubiquitination
0.37	GO:0006357	regulation of transcription by RNA polymerase II
0.36	GO:0007526	larval somatic muscle development
0.36	GO:0007474	imaginal disc-derived wing vein specification
0.36	GO:0045893	positive regulation of transcription, DNA-templated
0.35	GO:0071456	cellular response to hypoxia
0.35	GO:0043620	regulation of DNA-templated transcription in response to stress
0.35	GO:0043687	post-translational protein modification
0.35	GO:0006368	transcription elongation from RNA polymerase II promoter

0.61	GO:0003746	translation elongation factor activity
0.43	GO:0031625	ubiquitin protein ligase binding
0.37	GO:0003713	transcription coactivator activity
0.36	GO:0032403	protein complex binding
0.34	GO:0004842	ubiquitin-protein transferase activity
0.34	GO:0004252	serine-type endopeptidase activity
0.34	GO:0003743	translation initiation factor activity
0.33	GO:0003677	DNA binding
0.32	GO:0046872	metal ion binding

0.60	GO:0030891	VCB complex
0.60	GO:0070449	elongin complex
0.46	GO:0031466	Cul5-RING ubiquitin ligase complex
0.45	GO:0031462	Cul2-RING ubiquitin ligase complex
0.37	GO:0070062	extracellular exosome
0.36	GO:0005667	transcription factor complex
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.34	EC:3.4.21	GO:0004252
0.34	KEGG:R03876	GO:0004842

sp|Q15375|EPHA7_HUMAN
Ephrin type-A receptor 7
Search

EPHA7

0.93	EPH receptor A7

0.84	GO:0048013	ephrin receptor signaling pathway
0.73	GO:0018108	peptidyl-tyrosine phosphorylation
0.71	GO:0048755	branching morphogenesis of a nerve
0.71	GO:0048671	negative regulation of collateral sprouting
0.69	GO:0072178	nephric duct morphogenesis
0.69	GO:0051964	negative regulation of synapse assembly
0.68	GO:0043525	positive regulation of neuron apoptotic process
0.68	GO:0031290	retinal ganglion cell axon guidance
0.68	GO:0070372	regulation of ERK1 and ERK2 cascade
0.68	GO:0050730	regulation of peptidyl-tyrosine phosphorylation

0.85	GO:0005003	ephrin receptor activity
0.70	GO:0008046	axon guidance receptor activity
0.70	GO:0045499	chemorepellent activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.63

GO:0005887

integral component of plasma membrane

sp|Q15382|RHEB_HUMAN
GTP-binding protein Rheb
Search

RHEB

0.95	GTP-binding protein Rheb

0.80	GO:0032008	positive regulation of TOR signaling
0.61	GO:0007165	signal transduction
0.56	GO:2000074	regulation of type B pancreatic cell development
0.55	GO:0048714	positive regulation of oligodendrocyte differentiation
0.36	GO:0010800	positive regulation of peptidyl-threonine phosphorylation
0.36	GO:0006110	regulation of glycolytic process
0.36	GO:0019217	regulation of fatty acid metabolic process
0.36	GO:0071901	negative regulation of protein serine/threonine kinase activity
0.35	GO:0032147	activation of protein kinase activity
0.35	GO:0005977	glycogen metabolic process

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0019901	protein kinase binding
0.44	GO:0000287	magnesium ion binding
0.37	GO:0008607	phosphorylase kinase regulator activity
0.36	GO:0004862	cAMP-dependent protein kinase inhibitor activity
0.36	GO:0008603	cAMP-dependent protein kinase regulator activity

0.49	GO:0005681	spliceosomal complex
0.37	GO:0000139	Golgi membrane
0.37	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.36	GO:0031588	nucleotide-activated protein kinase complex
0.34	GO:0005765	lysosomal membrane
0.34	GO:0043025	neuronal cell body
0.34	GO:0030425	dendrite
0.30	GO:0016021	integral component of membrane

0.37

GO:0008607

sp|Q15386|UBE3C_HUMAN
Ubiquitin-protein ligase E3C
Search

UBE3C

0.92	Ubiquitin-protein ligase E3C

0.71

GO:0016567

protein ubiquitination

0.71	GO:0004842	ubiquitin-protein transferase activity
0.54	GO:0016874	ligase activity
0.45	GO:0061659	ubiquitin-like protein ligase activity
0.33	GO:0005515	protein binding

0.36	GO:0005737	cytoplasm
0.34	GO:0005634	nucleus
0.34	GO:1905369	endopeptidase complex
0.33	GO:0043234	protein complex
0.30	GO:0044425	membrane part

0.54	EC:6	GO:0016874
0.71	KEGG:R03876	GO:0004842

sp|Q15388|TOM20_HUMAN
Mitochondrial import receptor subunit TOM20 homolog
Search

TOMM20

0.90	Translocase of outer mitochondrial membrane 20

0.71	GO:0006605	protein targeting
0.51	GO:0072655	establishment of protein localization to mitochondrion
0.50	GO:0006839	mitochondrial transport
0.49	GO:0007005	mitochondrion organization
0.48	GO:0051031	tRNA transport
0.47	GO:0071806	protein transmembrane transport
0.44	GO:0017038	protein import
0.43	GO:0043623	cellular protein complex assembly
0.42	GO:1905242	response to 3,3',5-triiodo-L-thyronine
0.42	GO:0061024	membrane organization

0.50	GO:0030943	mitochondrion targeting sequence binding
0.49	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
0.46	GO:0051082	unfolded protein binding
0.32	GO:0003723	RNA binding
0.32	GO:0003677	DNA binding

0.84	GO:0005742	mitochondrial outer membrane translocase complex
0.50	GO:0044233	ER-mitochondrion membrane contact site
0.47	GO:0031307	integral component of mitochondrial outer membrane
0.36	GO:0031012	extracellular matrix
0.34	GO:0036128	CatSper complex
0.32	GO:0005634	nucleus

sp|Q15389|ANGP1_HUMAN
Angiopoietin-1
Search

ANGPT1

0.91	Angiopoietin 1

0.85	GO:0048014	Tie signaling pathway
0.79	GO:0001525	angiogenesis
0.61	GO:2000446	regulation of macrophage migration inhibitory factor signaling pathway
0.60	GO:0030210	heparin biosynthetic process
0.59	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity
0.59	GO:0043116	negative regulation of vascular permeability
0.59	GO:0002740	negative regulation of cytokine secretion involved in immune response
0.59	GO:0014842	regulation of skeletal muscle satellite cell proliferation
0.59	GO:0043535	regulation of blood vessel endothelial cell migration
0.58	GO:0002092	positive regulation of receptor internalization

0.85	GO:0030971	receptor tyrosine kinase binding
0.36	GO:0005172	vascular endothelial growth factor receptor binding
0.35	GO:0005088	Ras guanyl-nucleotide exchange factor activity

0.57	GO:0005902	microvillus
0.54	GO:0098857	membrane microdomain
0.52	GO:0005615	extracellular space
0.42	GO:0005886	plasma membrane
0.37	GO:1903561	extracellular vesicle
0.32	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

sp|Q15390|MTFR1_HUMAN
Mitochondrial fission regulator 1
Search

MTFR1

0.95	Mitochondrial fission regulator 1

0.65	GO:0000266	mitochondrial fission
0.61	GO:0009060	aerobic respiration
0.33	GO:0006414	translational elongation
0.33	GO:0007015	actin filament organization
0.32	GO:2001141	regulation of RNA biosynthetic process
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.33	GO:0003746	translation elongation factor activity
0.32	GO:0046872	metal ion binding

0.66	GO:0005829	cytosol
0.60	GO:0005739	mitochondrion
0.53	GO:0005886	plasma membrane
0.34	GO:0005853	eukaryotic translation elongation factor 1 complex
0.30	GO:0016021	integral component of membrane

sp|Q15391|P2Y14_HUMAN
P2Y purinoceptor 14
Search

P2RY14

0.97	Purinergic receptor P2Y G-protein coupled 14 transcript variant 2

0.85	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway
0.47	GO:0007596	blood coagulation
0.44	GO:0007194	negative regulation of adenylate cyclase activity
0.41	GO:0001774	microglial cell activation
0.34	GO:0006955	immune response

0.85	GO:0045028	G-protein coupled purinergic nucleotide receptor activity
0.37	GO:0045029	UDP-activated nucleotide receptor activity

0.44

GO:0005887

integral component of plasma membrane

sp|Q15392|DHC24_HUMAN
Delta(24)-sterol reductase
Search

DHCR24

0.91	24-dehydrocholesterol reductase

0.56	GO:0042987	amyloid precursor protein catabolic process
0.55	GO:0006695	cholesterol biosynthetic process
0.55	GO:0031639	plasminogen activation
0.55	GO:0030539	male genitalia development
0.54	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.54	GO:0043588	skin development
0.52	GO:0055114	oxidation-reduction process
0.50	GO:0009888	tissue development
0.48	GO:0006979	response to oxidative stress
0.46	GO:0061024	membrane organization

0.65	GO:0050660	flavin adenine dinucleotide binding
0.64	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors
0.60	GO:0000246	delta24(24-1) sterol reductase activity
0.57	GO:0042605	peptide antigen binding
0.48	GO:0019899	enzyme binding
0.42	GO:0050614	delta24-sterol reductase activity

0.48	GO:0005783	endoplasmic reticulum
0.44	GO:0005634	nucleus
0.38	GO:0000139	Golgi membrane
0.37	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.36	GO:0005856	cytoskeleton
0.36	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.64	EC:1.1	GO:0016614
0.60	KEGG:R05641	GO:0000246

sp|Q15393|SF3B3_HUMAN
Splicing factor 3B subunit 3
Search

SF3B3

0.90	Splicing factor 3B subunit 3

0.54	GO:0042177	negative regulation of protein catabolic process
0.43	GO:0000398	mRNA splicing, via spliceosome
0.33	GO:0006461	protein complex assembly

0.50	GO:0032403	protein complex binding
0.50	GO:0003676	nucleic acid binding

0.60	GO:0005634	nucleus
0.47	GO:0031974	membrane-enclosed lumen
0.44	GO:0030529	intracellular ribonucleoprotein complex
0.44	GO:1902494	catalytic complex
0.43	GO:0043232	intracellular non-membrane-bounded organelle
0.43	GO:0044446	intracellular organelle part
0.34	GO:0120114	Sm-like protein family complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q15397|PUM3_HUMAN
Pumilio homolog 3
Search

PUM3

0.90	Pumilio RNA binding family member 3

0.61	GO:0010835	regulation of protein ADP-ribosylation
0.45	GO:0006417	regulation of translation
0.44	GO:0008354	germ cell migration
0.37	GO:0008213	protein alkylation
0.36	GO:0043414	macromolecule methylation

0.59	GO:0003723	RNA binding
0.36	GO:0008168	methyltransferase activity
0.35	GO:0003677	DNA binding
0.34	GO:0005515	protein binding

0.53	GO:0005730	nucleolus
0.50	GO:0005783	endoplasmic reticulum
0.50	GO:0005654	nucleoplasm
0.49	GO:0005694	chromosome

0.36

GO:0008168

sp|Q15398|DLGP5_HUMAN
Disks large-associated protein 5
Search

DLGAP5

0.96	LOW QUALITY PROTEIN: disks large-associated protein 5

0.60	GO:0023052	signaling
0.53	GO:0006470	protein dephosphorylation
0.46	GO:0006461	protein complex assembly
0.39	GO:0007079	mitotic chromosome movement towards spindle pole
0.38	GO:0045842	positive regulation of mitotic metaphase/anaphase transition
0.37	GO:0008283	cell proliferation
0.37	GO:0045944	positive regulation of transcription by RNA polymerase II
0.34	GO:0007154	cell communication
0.34	GO:0051716	cellular response to stimulus

0.54	GO:0004721	phosphoprotein phosphatase activity
0.35	GO:0005515	protein binding
0.32	GO:0005509	calcium ion binding

0.63	GO:0031616	spindle pole centrosome
0.52	GO:0005829	cytosol
0.48	GO:0005634	nucleus
0.47	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.54

GO:0004721

sp|Q15399|TLR1_HUMAN
Toll-like receptor 1
Search

TLR1

0.90	Toll like receptor 1

0.86	GO:0070340	detection of bacterial lipopeptide
0.84	GO:0002755	MyD88-dependent toll-like receptor signaling pathway
0.82	GO:0050707	regulation of cytokine secretion
0.81	GO:0034130	toll-like receptor 1 signaling pathway
0.81	GO:0071725	response to triacyl bacterial lipopeptide
0.80	GO:0006954	inflammatory response
0.79	GO:0045087	innate immune response
0.77	GO:0042116	macrophage activation
0.68	GO:0045410	positive regulation of interleukin-6 biosynthetic process
0.64	GO:0034150	toll-like receptor 6 signaling pathway

0.70	GO:0004888	transmembrane signaling receptor activity
0.53	GO:0035663	Toll-like receptor 2 binding
0.46	GO:0046982	protein heterodimerization activity
0.44	GO:0071723	lipopeptide binding
0.37	GO:0042802	identical protein binding

0.51	GO:0035354	Toll-like receptor 1-Toll-like receptor 2 protein complex
0.48	GO:0098857	membrane microdomain
0.45	GO:0005794	Golgi apparatus
0.38	GO:0005887	integral component of plasma membrane
0.38	GO:0035355	Toll-like receptor 2-Toll-like receptor 6 protein complex
0.37	GO:0030670	phagocytic vesicle membrane

sp|Q15404|RSU1_HUMAN
Ras suppressor protein 1
Search

RSU1

0.95	Ras suppressor protein 1

0.84	GO:0010811	positive regulation of cell-substrate adhesion
0.75	GO:0043547	positive regulation of GTPase activity
0.46	GO:2000179	positive regulation of neural precursor cell proliferation
0.44	GO:0007265	Ras protein signal transduction

0.37

GO:0005515

protein binding

0.81	GO:0005925	focal adhesion
0.44	GO:0070062	extracellular exosome
0.38	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q15406|NR6A1_HUMAN
Nuclear receptor subfamily 6 group A member 1
Search

NR6A1

0.96	Nuclear receptor subfamily 6 group A member 1

0.77	GO:0043401	steroid hormone mediated signaling pathway
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.51	GO:0007276	gamete generation
0.49	GO:1902680	positive regulation of RNA biosynthetic process
0.48	GO:1902679	negative regulation of RNA biosynthetic process
0.47	GO:0030522	intracellular receptor signaling pathway
0.39	GO:0030917	midbrain-hindbrain boundary development

0.78	GO:0003707	steroid hormone receptor activity
0.62	GO:0043565	sequence-specific DNA binding
0.60	GO:0008270	zinc ion binding
0.59	GO:0003700	DNA binding transcription factor activity
0.53	GO:0001012	RNA polymerase II regulatory region DNA binding
0.51	GO:0003690	double-stranded DNA binding
0.51	GO:0042803	protein homodimerization activity
0.34	GO:0035326	enhancer binding
0.33	GO:0003682	chromatin binding
0.33	GO:0005543	phospholipid binding

0.60	GO:0005634	nucleus
0.52	GO:0005667	transcription factor complex
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.33	GO:0005737	cytoplasm

sp|Q15413|RYR3_HUMAN
Ryanodine receptor 3
Search

RYR3

0.85	Ryanodine receptor type 3

0.84	GO:0051209	release of sequestered calcium ion into cytosol
0.44	GO:0071313	cellular response to caffeine
0.43	GO:0051481	negative regulation of cytosolic calcium ion concentration
0.42	GO:0006936	muscle contraction
0.42	GO:0051592	response to calcium ion
0.41	GO:0071286	cellular response to magnesium ion
0.41	GO:0071318	cellular response to ATP
0.40	GO:0051289	protein homotetramerization
0.40	GO:1903779	regulation of cardiac conduction
0.38	GO:0097050	type B pancreatic cell apoptotic process

0.85	GO:0005219	ryanodine-sensitive calcium-release channel activity
0.67	GO:0005509	calcium ion binding
0.45	GO:0048763	calcium-induced calcium release activity
0.41	GO:0005516	calmodulin binding
0.39	GO:0043924	suramin binding
0.38	GO:0034236	protein kinase A catalytic subunit binding
0.37	GO:0034237	protein kinase A regulatory subunit binding
0.37	GO:0042802	identical protein binding
0.36	GO:0043621	protein self-association
0.32	GO:0003676	nucleic acid binding

0.45	GO:0016529	sarcoplasmic reticulum
0.41	GO:0005789	endoplasmic reticulum membrane
0.41	GO:0098588	bounding membrane of organelle
0.41	GO:0030314	junctional membrane complex
0.40	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0005886	plasma membrane
0.37	GO:0030018	Z disc
0.37	GO:0034704	calcium channel complex
0.36	GO:0005790	smooth endoplasmic reticulum

sp|Q15415|RBY1F_HUMAN
RNA-binding motif protein, Y chromosome, family 1 member F/J
Search

0.62	RNA binding motif protein, X-linked

0.49	GO:0006509	membrane protein ectodomain proteolysis
0.48	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.48	GO:0071347	cellular response to interleukin-1
0.45	GO:0008380	RNA splicing
0.45	GO:0006366	transcription by RNA polymerase II
0.45	GO:0045944	positive regulation of transcription by RNA polymerase II
0.45	GO:0051259	protein oligomerization
0.44	GO:0006397	mRNA processing
0.43	GO:0048025	negative regulation of mRNA splicing, via spliceosome
0.43	GO:0048026	positive regulation of mRNA splicing, via spliceosome

0.59	GO:0003723	RNA binding
0.47	GO:0001047	core promoter binding
0.45	GO:0003682	chromatin binding
0.43	GO:0042802	identical protein binding
0.42	GO:0019904	protein domain specific binding

0.51	GO:0044530	supraspliceosomal complex
0.48	GO:0005719	nuclear euchromatin
0.47	GO:0071013	catalytic step 2 spliceosome
0.47	GO:0070062	extracellular exosome
0.34	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q15417|CNN3_HUMAN
Calponin-3
Search

CNN3

0.87

Calponin

0.82	GO:0031032	actomyosin structure organization
0.51	GO:0030855	epithelial cell differentiation
0.50	GO:0098609	cell-cell adhesion
0.36	GO:0032780	negative regulation of ATPase activity
0.36	GO:0006488	dolichol-linked oligosaccharide biosynthetic process
0.36	GO:1904706	negative regulation of vascular smooth muscle cell proliferation

0.77	GO:0005516	calmodulin binding
0.74	GO:0003779	actin binding
0.55	GO:0098641	cadherin binding involved in cell-cell adhesion
0.37	GO:0008017	microtubule binding

0.53	GO:0005913	cell-cell adherens junction
0.49	GO:0015629	actin cytoskeleton
0.46	GO:0005829	cytosol
0.37	GO:0043197	dendritic spine
0.37	GO:0014069	postsynaptic density
0.36	GO:0043025	neuronal cell body
0.35	GO:0005925	focal adhesion

sp|Q15418|KS6A1_HUMAN
Ribosomal protein S6 kinase alpha-1
Search

RPS6KA1

0.75	Ribosomal protein S6 kinase alpha-1

0.63	GO:0006468	protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.57	GO:2000491	positive regulation of hepatic stellate cell activation
0.52	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.49	GO:0006915	apoptotic process
0.48	GO:0045944	positive regulation of transcription by RNA polymerase II
0.39	GO:0072574	hepatocyte proliferation
0.35	GO:0043555	regulation of translation in response to stress
0.35	GO:0030307	positive regulation of cell growth
0.34	GO:0043620	regulation of DNA-templated transcription in response to stress

0.70	GO:0004674	protein serine/threonine kinase activity
0.64	GO:0000287	magnesium ion binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0004712	protein serine/threonine/tyrosine kinase activity
0.35	GO:0008134	transcription factor binding
0.35	GO:0031492	nucleosomal DNA binding

0.46	GO:0005829	cytosol
0.45	GO:0005634	nucleus
0.36	GO:0043232	intracellular non-membrane-bounded organelle
0.35	GO:0044446	intracellular organelle part
0.34	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0031974	membrane-enclosed lumen

0.70

GO:0004674

sp|Q15424|SAFB1_HUMAN
Scaffold attachment factor B1
Search

sp|Q15427|SF3B4_HUMAN
Splicing factor 3B subunit 4
Search

SF3B4

0.78	Spliceosome-associated protein 49

0.47	GO:0048026	positive regulation of mRNA splicing, via spliceosome
0.34	GO:0008380	RNA splicing
0.33	GO:0006397	mRNA processing
0.32	GO:0055114	oxidation-reduction process

0.59	GO:0003723	RNA binding
0.42	GO:0005199	structural constituent of cell wall
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0016491	oxidoreductase activity
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0005515	protein binding

0.49	GO:0005689	U12-type spliceosomal complex
0.32	GO:0005654	nucleoplasm

0.32

EC:1

GO:0016491

sp|Q15428|SF3A2_HUMAN
Splicing factor 3A subunit 2
Search

SF3A2

0.49	Splicing factor 3A subunit

0.50	GO:0006397	mRNA processing
0.46	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
0.46	GO:0022618	ribonucleoprotein complex assembly
0.40	GO:0010976	positive regulation of neuron projection development
0.37	GO:0008406	gonad development
0.36	GO:0010469	regulation of receptor activity

0.63	GO:0008270	zinc ion binding
0.51	GO:0003676	nucleic acid binding
0.36	GO:0008083	growth factor activity
0.34	GO:0005199	structural constituent of cell wall

0.61	GO:0005634	nucleus
0.47	GO:0120114	Sm-like protein family complex
0.46	GO:1902494	catalytic complex
0.46	GO:0030529	intracellular ribonucleoprotein complex
0.44	GO:0044446	intracellular organelle part
0.37	GO:0043233	organelle lumen
0.34	GO:0005576	extracellular region

sp|Q15431|SYCP1_HUMAN
Synaptonemal complex protein 1
Search

SYCP1

0.97	Synaptonemal complex protein 1

0.85	GO:0007130	synaptonemal complex assembly
0.68	GO:0000711	meiotic DNA repair synthesis
0.67	GO:0035092	sperm chromatin condensation
0.67	GO:0051026	chiasma assembly
0.58	GO:0032880	regulation of protein localization
0.38	GO:0051301	cell division
0.36	GO:0010469	regulation of receptor activity
0.35	GO:0030522	intracellular receptor signaling pathway
0.35	GO:0043401	steroid hormone mediated signaling pathway
0.33	GO:0006351	transcription, DNA-templated

0.36	GO:0005179	hormone activity
0.36	GO:0003677	DNA binding
0.36	GO:0004887	thyroid hormone receptor activity
0.35	GO:0003707	steroid hormone receptor activity
0.33	GO:0008270	zinc ion binding

0.85	GO:0000795	synaptonemal complex
0.67	GO:0001673	male germ cell nucleus
0.40	GO:0000775	chromosome, centromeric region
0.35	GO:0005576	extracellular region
0.32	GO:0005654	nucleoplasm

sp|Q15434|RBMS2_HUMAN
RNA-binding motif, single-stranded-interacting protein 2
Search

0.87	RNA binding motif single stranded interacting protein 2

0.34	GO:0006396	RNA processing
0.34	GO:0006260	DNA replication

0.59	GO:0003723	RNA binding
0.34	GO:0003697	single-stranded DNA binding
0.33	GO:0003690	double-stranded DNA binding
0.33	GO:0005515	protein binding

0.43	GO:0005829	cytosol
0.35	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|Q15435|PP1R7_HUMAN
Protein phosphatase 1 regulatory subunit 7
Search

PPP1R7

0.91	Phosphatase 1 regulatory subunit 7

0.83	GO:0035307	positive regulation of protein dephosphorylation
0.70	GO:0007059	chromosome segregation
0.39	GO:0043666	regulation of phosphoprotein phosphatase activity

0.39	GO:0019888	protein phosphatase regulator activity
0.39	GO:0005515	protein binding

0.65	GO:0005694	chromosome
0.44	GO:0005634	nucleus
0.43	GO:0070062	extracellular exosome
0.34	GO:0005737	cytoplasm

sp|Q15436|SC23A_HUMAN
Protein transport protein Sec23A
Search

SEC23A

0.97	Sec23 homolog A, COPII coat complex component

0.81	GO:0090114	COPII-coated vesicle budding
0.69	GO:0006886	intracellular protein transport
0.66	GO:0035459	cargo loading into vesicle
0.62	GO:0051668	localization within membrane
0.54	GO:0048702	embryonic neurocranium morphogenesis
0.53	GO:0035138	pectoral fin morphogenesis
0.51	GO:0051216	cartilage development
0.37	GO:0048821	erythrocyte development

0.63

GO:0008270

zinc ion binding

0.80	GO:0030127	COPII vesicle coat
0.72	GO:0000139	Golgi membrane
0.65	GO:0070971	endoplasmic reticulum exit site
0.62	GO:0048471	perinuclear region of cytoplasm
0.57	GO:0019898	extrinsic component of membrane
0.53	GO:0005829	cytosol

sp|Q15437|SC23B_HUMAN
Protein transport protein Sec23B
Search

SEC23B

0.76	Sec23 homolog B, COPII coat complex component

0.82	GO:0090114	COPII-coated vesicle budding
0.69	GO:0006886	intracellular protein transport
0.57	GO:0035459	cargo loading into vesicle
0.56	GO:0048702	embryonic neurocranium morphogenesis
0.55	GO:0051668	localization within membrane
0.53	GO:0051216	cartilage development
0.52	GO:0048821	erythrocyte development
0.42	GO:0035138	pectoral fin morphogenesis

0.62

GO:0008270

zinc ion binding

0.80	GO:0030127	COPII vesicle coat
0.74	GO:0000139	Golgi membrane
0.64	GO:0048471	perinuclear region of cytoplasm
0.59	GO:0005783	endoplasmic reticulum
0.51	GO:0019898	extrinsic component of membrane
0.48	GO:0005829	cytosol

sp|Q15438|CYH1_HUMAN
Cytohesin-1
Search

CYTH1

0.94	Putative pattern-formation protein/guanine nucleotide exchange factor

0.81	GO:0032012	regulation of ARF protein signal transduction
0.66	GO:0065009	regulation of molecular function
0.49	GO:0030155	regulation of cell adhesion
0.41	GO:0090162	establishment of epithelial cell polarity
0.36	GO:0048193	Golgi vesicle transport
0.36	GO:0048518	positive regulation of biological process

0.82	GO:0005086	ARF guanyl-nucleotide exchange factor activity
0.39	GO:0008289	lipid binding
0.34	GO:0043168	anion binding

0.41	GO:0005886	plasma membrane
0.40	GO:0005923	bicellular tight junction
0.40	GO:0005912	adherens junction
0.39	GO:0098562	cytoplasmic side of membrane
0.39	GO:0019898	extrinsic component of membrane
0.38	GO:0005737	cytoplasm
0.38	GO:0001726	ruffle
0.35	GO:0005654	nucleoplasm
0.35	GO:0098588	bounding membrane of organelle
0.34	GO:0031984	organelle subcompartment

sp|Q15459|SF3A1_HUMAN
Splicing factor 3A subunit 1
Search

SF3A1

0.91	Splicing factor 3 subunit 1

0.61	GO:0006396	RNA processing
0.51	GO:0016071	mRNA metabolic process
0.49	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.45	GO:0022618	ribonucleoprotein complex assembly

0.57	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.58	GO:0005686	U2 snRNP
0.57	GO:0071013	catalytic step 2 spliceosome
0.57	GO:0005684	U2-type spliceosomal complex
0.56	GO:0016607	nuclear speck
0.48	GO:0071010	prespliceosome

sp|Q15464|SHB_HUMAN
SH2 domain-containing adapter protein B
Search

SHB

0.88	SH2 domain-containing adapter protein B

0.76	GO:0009967	positive regulation of signal transduction
0.70	GO:1900194	negative regulation of oocyte maturation
0.69	GO:0045624	positive regulation of T-helper cell differentiation
0.69	GO:0071425	hematopoietic stem cell proliferation
0.67	GO:0042100	B cell proliferation
0.66	GO:0050852	T cell receptor signaling pathway
0.63	GO:0045931	positive regulation of mitotic cell cycle
0.63	GO:0048514	blood vessel morphogenesis
0.63	GO:0006469	negative regulation of protein kinase activity
0.41	GO:0006915	apoptotic process

0.85	GO:0005070	SH3/SH2 adaptor activity
0.46	GO:0001784	phosphotyrosine residue binding

0.42	GO:0036464	cytoplasmic ribonucleoprotein granule
0.40	GO:0005654	nucleoplasm
0.40	GO:0005829	cytosol
0.36	GO:0005886	plasma membrane

sp|Q15465|SHH_HUMAN
Sonic hedgehog protein
Search

SHH

0.69	Sonic hedgehog

0.74	GO:0007267	cell-cell signaling
0.71	GO:0016539	intein-mediated protein splicing
0.69	GO:0007275	multicellular organism development
0.59	GO:0061189	positive regulation of sclerotome development
0.58	GO:2000062	negative regulation of ureter smooth muscle cell differentiation
0.58	GO:2000357	negative regulation of kidney smooth muscle cell differentiation
0.58	GO:2000358	positive regulation of kidney smooth muscle cell differentiation
0.58	GO:2000063	positive regulation of ureter smooth muscle cell differentiation
0.58	GO:0060782	regulation of mesenchymal cell proliferation involved in prostate gland development
0.58	GO:1905327	tracheoesophageal septum formation

0.59	GO:0008233	peptidase activity
0.58	GO:0005113	patched binding
0.56	GO:0043237	laminin-1 binding
0.50	GO:0005539	glycosaminoglycan binding
0.49	GO:0005509	calcium ion binding
0.45	GO:0008270	zinc ion binding
0.38	GO:0016015	morphogen activity

0.62	GO:0005615	extracellular space
0.51	GO:0098857	membrane microdomain
0.51	GO:0005578	proteinaceous extracellular matrix
0.49	GO:0009986	cell surface
0.48	GO:0005886	plasma membrane
0.37	GO:0005622	intracellular
0.35	GO:0012505	endomembrane system
0.35	GO:0043233	organelle lumen
0.34	GO:0043227	membrane-bounded organelle
0.33	GO:0043025	neuronal cell body

0.59

GO:0008233

sp|Q15466|NR0B2_HUMAN
Nuclear receptor subfamily 0 group B member 2
Search

NR0B2

0.96	Small heterodimer partner

0.78	GO:0043401	steroid hormone mediated signaling pathway
0.64	GO:0043433	negative regulation of DNA binding transcription factor activity
0.61	GO:0007219	Notch signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:1903507	negative regulation of nucleic acid-templated transcription
0.55	GO:0010628	positive regulation of gene expression
0.54	GO:0010629	negative regulation of gene expression
0.49	GO:0030325	adrenal gland development
0.43	GO:0035902	response to immobilization stress
0.43	GO:0033327	Leydig cell differentiation

0.78	GO:0003707	steroid hormone receptor activity
0.63	GO:0003714	transcription corepressor activity
0.60	GO:0019904	protein domain specific binding
0.59	GO:0042803	protein homodimerization activity
0.54	GO:0003677	DNA binding
0.45	GO:0035257	nuclear hormone receptor binding
0.42	GO:0042975	peroxisome proliferator activated receptor binding
0.41	GO:0004879	nuclear receptor activity
0.39	GO:0032403	protein complex binding
0.37	GO:0003723	RNA binding

0.61	GO:0005634	nucleus
0.43	GO:0042788	polysomal ribosome
0.39	GO:0005815	microtubule organizing center
0.38	GO:0031974	membrane-enclosed lumen
0.36	GO:0043234	protein complex
0.30	GO:0016020	membrane

sp|Q15468|STIL_HUMAN
SCL-interrupting locus protein
Search

STIL

0.97	STIL, centriolar assembly protein

0.85	GO:0071539	protein localization to centrosome
0.85	GO:0046599	regulation of centriole replication
0.85	GO:0051298	centrosome duplication
0.83	GO:0007052	mitotic spindle organization
0.41	GO:0033504	floor plate development
0.41	GO:0030903	notochord development
0.40	GO:0001947	heart looping
0.40	GO:0001843	neural tube closure
0.40	GO:0000578	embryonic axis specification
0.40	GO:0035264	multicellular organism growth

0.83	GO:0005814	centriole
0.78	GO:0005813	centrosome

sp|Q15475|SIX1_HUMAN
Homeobox protein SIX1
Search

SIX1

0.96	SIX homeobox 1

0.75	GO:0072074	kidney mesenchyme development
0.74	GO:0042474	middle ear morphogenesis
0.74	GO:0090189	regulation of branching involved in ureteric bud morphogenesis
0.74	GO:0008283	cell proliferation
0.72	GO:0072088	nephron epithelium morphogenesis
0.72	GO:0001656	metanephros development
0.71	GO:0048701	embryonic cranial skeleton morphogenesis
0.70	GO:0001708	cell fate specification
0.68	GO:2000729	positive regulation of mesenchymal cell proliferation involved in ureter development
0.67	GO:0034504	protein localization to nucleus

0.69	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.68	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.57	GO:0003682	chromatin binding
0.51	GO:0032403	protein complex binding
0.51	GO:0008134	transcription factor binding

0.61	GO:0005634	nucleus
0.56	GO:0005667	transcription factor complex
0.52	GO:0070013	intracellular organelle lumen
0.47	GO:0043232	intracellular non-membrane-bounded organelle
0.46	GO:0044446	intracellular organelle part

sp|Q15477|SKIV2_HUMAN
Helicase SKI2W
Search

SKIV2L

0.97	Superkiller viralicidic activity 2 (S. cerevisiae homolog)-like

0.72	GO:0006401	RNA catabolic process
0.44	GO:0016071	mRNA metabolic process
0.44	GO:0010629	negative regulation of gene expression
0.35	GO:0000381	regulation of alternative mRNA splicing, via spliceosome

0.76	GO:0003724	RNA helicase activity
0.59	GO:0003723	RNA binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0008186	RNA-dependent ATPase activity
0.45	GO:0070035	purine NTP-dependent helicase activity
0.32	GO:0016779	nucleotidyltransferase activity

0.63	GO:0055087	Ski complex
0.34	GO:0005634	nucleus
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.76

GO:0003724

sp|Q15485|FCN2_HUMAN
Ficolin-2
Search

FCN2

0.88	Ficolin (Collagen/fibrinogen domain containing) 1

0.77	GO:0043654	recognition of apoptotic cell
0.75	GO:0001867	complement activation, lectin pathway
0.69	GO:0002752	cell surface pattern recognition receptor signaling pathway
0.67	GO:2000484	positive regulation of interleukin-8 secretion
0.65	GO:0046597	negative regulation of viral entry into host cell
0.62	GO:0034394	protein localization to cell surface
0.60	GO:0008228	opsonization
0.56	GO:0050830	defense response to Gram-positive bacterium
0.56	GO:0050829	defense response to Gram-negative bacterium
0.55	GO:0007186	G-protein coupled receptor signaling pathway

0.73	GO:0033691	sialic acid binding
0.65	GO:0008329	signaling pattern recognition receptor activity
0.61	GO:2001065	mannan binding
0.59	GO:0003823	antigen binding
0.58	GO:0001664	G-protein coupled receptor binding
0.57	GO:0043394	proteoglycan binding
0.57	GO:0048306	calcium-dependent protein binding
0.45	GO:0046872	metal ion binding
0.43	GO:0004252	serine-type endopeptidase activity

0.68	GO:0031232	extrinsic component of external side of plasma membrane
0.63	GO:0005581	collagen trimer
0.54	GO:0005576	extracellular region
0.44	GO:0031982	vesicle
0.38	GO:0012505	endomembrane system
0.38	GO:0043233	organelle lumen
0.36	GO:0044446	intracellular organelle part
0.36	GO:0044444	cytoplasmic part

0.43

GO:0004252

sp|Q15486|GUSP1_HUMAN
Putative inactive beta-glucuronidase-like protein SMA3
Search

0.95	Beta-glucuronidase-like protein SMA3

0.59	GO:0005975	carbohydrate metabolic process
0.38	GO:0001501	skeletal system development
0.37	GO:0007399	nervous system development
0.36	GO:0030214	hyaluronan catabolic process
0.36	GO:0046677	response to antibiotic
0.36	GO:0043312	neutrophil degranulation
0.35	GO:0006907	pinocytosis
0.35	GO:0008333	endosome to lysosome transport
0.34	GO:0006898	receptor-mediated endocytosis

0.82	GO:0004566	beta-glucuronidase activity
0.50	GO:0019904	protein domain specific binding
0.48	GO:0005102	receptor binding
0.34	GO:0030246	carbohydrate binding

0.75	GO:0005764	lysosome
0.48	GO:0005615	extracellular space
0.37	GO:1903561	extracellular vesicle
0.36	GO:1904813	ficolin-1-rich granule lumen
0.36	GO:0034774	secretory granule lumen
0.36	GO:0005775	vacuolar lumen
0.34	GO:0009986	cell surface
0.34	GO:0005783	endoplasmic reticulum
0.30	GO:0031224	intrinsic component of membrane

0.82

EC:3.2.1.31

GO:0004566

sp|Q15493|RGN_HUMAN
Regucalcin
Search

RGN

0.84	Epididymis secretory protein Li 41

0.68	GO:0050790	regulation of catalytic activity
0.61	GO:0019853	L-ascorbic acid biosynthetic process
0.45	GO:0050848	regulation of calcium-mediated signaling
0.44	GO:0006874	cellular calcium ion homeostasis
0.41	GO:0044093	positive regulation of molecular function
0.41	GO:1903625	negative regulation of DNA catabolic process
0.41	GO:1901318	negative regulation of flagellated sperm motility
0.41	GO:1903011	negative regulation of bone development
0.41	GO:0045019	negative regulation of nitric oxide biosynthetic process
0.40	GO:0010867	positive regulation of triglyceride biosynthetic process

0.70	GO:0030234	enzyme regulator activity
0.70	GO:0005509	calcium ion binding
0.61	GO:0004341	gluconolactonase activity
0.47	GO:0008270	zinc ion binding
0.35	GO:0008081	phosphoric diester hydrolase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003676	nucleic acid binding

0.46	GO:0005634	nucleus
0.43	GO:0005576	extracellular region
0.40	GO:0005737	cytoplasm

0.61

EC:3.1.1.17

GO:0004341

sp|Q15506|SP17_HUMAN
Sperm surface protein Sp17
Search

SPA17

0.96	Sperm autoantigenic protein 17

0.84	GO:0007339	binding of sperm to zona pellucida
0.44	GO:0035023	regulation of Rho protein signal transduction
0.41	GO:0065009	regulation of molecular function
0.39	GO:0003341	cilium movement
0.36	GO:0007283	spermatogenesis
0.35	GO:0035385	Roundabout signaling pathway
0.35	GO:0007411	axon guidance
0.34	GO:0040008	regulation of growth
0.33	GO:0030239	myofibril assembly
0.33	GO:0060041	retina development in camera-type eye

0.44	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.36	GO:0008201	heparin binding

0.66	GO:0035686	sperm fibrous sheath
0.64	GO:0097228	sperm principal piece
0.60	GO:0009897	external side of plasma membrane
0.41	GO:0005737	cytoplasm
0.35	GO:0030424	axon
0.33	GO:0005634	nucleus
0.32	GO:0099512	supramolecular fiber
0.32	GO:0043232	intracellular non-membrane-bounded organelle

sp|Q15513|SPHAR_HUMAN
Protein SPHAR
Search

sp|Q15517|CDSN_HUMAN
Corneodesmosin
Search

CDSN

0.97	Corneodesmosin

0.86	GO:0043589	skin morphogenesis
0.45	GO:1905716	negative regulation of cornification
0.45	GO:0003336	corneocyte desquamation
0.42	GO:0070268	cornification
0.40	GO:0098609	cell-cell adhesion

0.50

GO:0042803

protein homodimerization activity

0.58	GO:0005615	extracellular space
0.43	GO:0030057	desmosome
0.42	GO:0001533	cornified envelope
0.40	GO:1903561	extracellular vesicle
0.33	GO:0031012	extracellular matrix
0.31	GO:0005737	cytoplasm

sp|Q15526|SURF1_HUMAN
Surfeit locus protein 1
Search

0.49	GO:0033617	mitochondrial respiratory chain complex IV assembly
0.43	GO:0021522	spinal cord motor neuron differentiation
0.43	GO:0006754	ATP biosynthetic process
0.43	GO:1902600	hydrogen ion transmembrane transport
0.42	GO:0022900	electron transport chain
0.41	GO:0048568	embryonic organ development
0.41	GO:0006119	oxidative phosphorylation
0.37	GO:0042331	phototaxis
0.37	GO:0002168	instar larval development
0.36	GO:0007632	visual behavior

0.44	GO:0015002	heme-copper terminal oxidase activity
0.44	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.43	GO:0015078	hydrogen ion transmembrane transporter activity
0.43	GO:0009055	electron transfer activity
0.35	GO:0051287	NAD binding
0.35	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
0.33	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity
0.33	GO:0005515	protein binding
0.33	GO:0016934	extracellularly glycine-gated chloride channel activity
0.33	GO:0000049	tRNA binding

0.60	GO:0031966	mitochondrial membrane
0.60	GO:0019866	organelle inner membrane
0.35	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.33	GO:0070469	respiratory chain
0.32	GO:0045211	postsynaptic membrane
0.30	GO:0016021	integral component of membrane

0.44

EC:1.9.3

GO:0016676

sp|Q15527|SURF2_HUMAN
Surfeit locus protein 2
Search

SURF2

0.97	Surfeit gene 2

0.40	GO:0007030	Golgi organization
0.39	GO:0010638	positive regulation of organelle organization
0.38	GO:0006468	protein phosphorylation

0.38	GO:0004672	protein kinase activity
0.36	GO:0032559	adenyl ribonucleotide binding
0.36	GO:0008144	drug binding
0.36	GO:0035639	purine ribonucleoside triphosphate binding

0.77	GO:0016607	nuclear speck
0.70	GO:0005730	nucleolus
0.54	GO:0005886	plasma membrane
0.41	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment

sp|Q15528|MED22_HUMAN
Mediator of RNA polymerase II transcription subunit 22
Search

MED22

0.90	Mediator of RNA polymerase II transcription subunit 22

0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.37	GO:0006351	transcription, DNA-templated
0.33	GO:0005975	carbohydrate metabolic process

0.79	GO:0001104	RNA polymerase II transcription cofactor activity
0.33	GO:0005515	protein binding
0.33	GO:0016758	transferase activity, transferring hexosyl groups

0.77	GO:0016592	mediator complex
0.32	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.33

GO:0016758

sp|Q15532|SSXT_HUMAN
Protein SSXT
Search

SS18

0.97	SS18, nBAF chromatin remodeling complex subunit

0.78	GO:0097150	neuronal stem cell population maintenance
0.74	GO:0048013	ephrin receptor signaling pathway
0.68	GO:0000226	microtubule cytoskeleton organization
0.67	GO:0045944	positive regulation of transcription by RNA polymerase II
0.67	GO:0000902	cell morphogenesis
0.63	GO:0042493	response to drug
0.57	GO:0035556	intracellular signal transduction

0.79

GO:0003713

transcription coactivator activity

0.75	GO:0071564	npBAF complex
0.74	GO:0005881	cytoplasmic microtubule

sp|Q15542|TAF5_HUMAN
Transcription initiation factor TFIID subunit 5
Search

TAF5

0.91	TATA-box binding protein associated factor 5

0.79	GO:0006367	transcription initiation from RNA polymerase II promoter
0.78	GO:0016573	histone acetylation
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.39	GO:0006413	translational initiation

0.80	GO:0004402	histone acetyltransferase activity
0.76	GO:0044212	transcription regulatory region DNA binding
0.74	GO:0042802	identical protein binding
0.68	GO:0046983	protein dimerization activity
0.61	GO:0003700	DNA binding transcription factor activity
0.39	GO:0003743	translation initiation factor activity

0.86	GO:0033276	transcription factor TFTC complex
0.80	GO:0005669	transcription factor TFIID complex
0.75	GO:0000790	nuclear chromatin
0.74	GO:0015629	actin cytoskeleton

0.80

GO:0004402

sp|Q15543|TAF13_HUMAN
Transcription initiation factor TFIID subunit 13
Search

TAF13

0.91	Transcription initiation factor TFIID subunit 13

0.76	GO:0006366	transcription by RNA polymerase II
0.57	GO:0006413	translational initiation
0.42	GO:0006357	regulation of transcription by RNA polymerase II
0.35	GO:0009301	snRNA transcription
0.35	GO:1901796	regulation of signal transduction by p53 class mediator
0.34	GO:0006354	DNA-templated transcription, elongation
0.33	GO:0006352	DNA-templated transcription, initiation

0.74	GO:0046982	protein heterodimerization activity
0.58	GO:0003743	translation initiation factor activity
0.51	GO:0008022	protein C-terminus binding
0.44	GO:0003712	transcription cofactor activity
0.40	GO:0003677	DNA binding
0.33	GO:0003700	DNA binding transcription factor activity

0.50	GO:0005669	transcription factor TFIID complex
0.47	GO:0005730	nucleolus

sp|Q15544|TAF11_HUMAN
Transcription initiation factor TFIID subunit 11
Search

TAF11

0.90	Transcription initiation factor TFIID subunit 11

0.79	GO:0006367	transcription initiation from RNA polymerase II promoter
0.56	GO:0006413	translational initiation
0.56	GO:0043923	positive regulation by host of viral transcription
0.51	GO:0070897	DNA-templated transcriptional preinitiation complex assembly
0.44	GO:1903506	regulation of nucleic acid-templated transcription
0.41	GO:1901092	positive regulation of protein tetramerization
0.41	GO:1900370	positive regulation of RNA interference
0.36	GO:0042795	snRNA transcription by RNA polymerase II
0.36	GO:1901796	regulation of signal transduction by p53 class mediator
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.74	GO:0046982	protein heterodimerization activity
0.57	GO:0042809	vitamin D receptor binding
0.57	GO:0003743	translation initiation factor activity
0.56	GO:0046966	thyroid hormone receptor binding
0.55	GO:0003713	transcription coactivator activity
0.54	GO:0047485	protein N-terminus binding
0.40	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly
0.36	GO:0003677	DNA binding
0.33	GO:0070006	metalloaminopeptidase activity
0.32	GO:0046872	metal ion binding

0.61	GO:0005634	nucleus
0.54	GO:0000428	DNA-directed RNA polymerase complex
0.54	GO:0005667	transcription factor complex
0.50	GO:0031974	membrane-enclosed lumen
0.48	GO:0005794	Golgi apparatus
0.45	GO:0044446	intracellular organelle part
0.40	GO:0070578	RISC-loading complex

sp|Q15545|TAF7_HUMAN
Transcription initiation factor TFIID subunit 7
Search

TAF7

0.87	Transcription initiation factor TFIID subunit 7

0.79	GO:0006367	transcription initiation from RNA polymerase II promoter
0.58	GO:0006413	translational initiation
0.52	GO:0035067	negative regulation of histone acetylation
0.50	GO:0030520	intracellular estrogen receptor signaling pathway
0.49	GO:0006357	regulation of transcription by RNA polymerase II
0.49	GO:0006469	negative regulation of protein kinase activity
0.48	GO:0070897	DNA-templated transcriptional preinitiation complex assembly
0.46	GO:0045893	positive regulation of transcription, DNA-templated
0.46	GO:0045892	negative regulation of transcription, DNA-templated
0.38	GO:0000296	spermine transport

0.58	GO:0003743	translation initiation factor activity
0.58	GO:0035035	histone acetyltransferase binding
0.54	GO:0061628	H3K27me3 modified histone binding
0.54	GO:0003713	transcription coactivator activity
0.53	GO:0042809	vitamin D receptor binding
0.52	GO:0046966	thyroid hormone receptor binding
0.52	GO:0044212	transcription regulatory region DNA binding
0.47	GO:0046982	protein heterodimerization activity
0.42	GO:0003700	DNA binding transcription factor activity

0.80	GO:0005669	transcription factor TFIID complex
0.52	GO:0033276	transcription factor TFTC complex
0.52	GO:0008024	cyclin/CDK positive transcription elongation factor complex
0.51	GO:0071339	MLL1 complex
0.46	GO:0005794	Golgi apparatus
0.30	GO:0016020	membrane

sp|Q15546|PAQRB_HUMAN
Monocyte to macrophage differentiation factor
Search

MMD

0.97	Monocyte to macrophage differentiation associated

0.76	GO:0019835	cytolysis
0.51	GO:0045666	positive regulation of neuron differentiation
0.49	GO:0045860	positive regulation of protein kinase activity
0.48	GO:0032880	regulation of protein localization
0.43	GO:0006468	protein phosphorylation
0.42	GO:0003007	heart morphogenesis
0.41	GO:0036302	atrioventricular canal development
0.40	GO:0046578	regulation of Ras protein signal transduction
0.40	GO:0003197	endocardial cushion development
0.40	GO:0072132	mesenchyme morphogenesis

0.43	GO:0004672	protein kinase activity
0.33	GO:0004872	receptor activity

0.46	GO:0005794	Golgi apparatus
0.38	GO:0031902	late endosome membrane
0.37	GO:0005765	lysosomal membrane
0.37	GO:0048471	perinuclear region of cytoplasm
0.33	GO:0005887	integral component of plasma membrane

sp|Q15554|TERF2_HUMAN
Telomeric repeat-binding factor 2
Search

TERF2

0.80	Telomeric repeat-binding factor 2

0.85	GO:0031848	protection from non-homologous end joining at telomere
0.69	GO:1905839	negative regulation of telomeric D-loop disassembly
0.68	GO:1903770	negative regulation of beta-galactosidase activity
0.68	GO:1905778	negative regulation of exonuclease activity
0.68	GO:0032208	negative regulation of telomere maintenance via recombination
0.67	GO:0061820	telomeric D-loop disassembly
0.67	GO:1904430	negative regulation of t-circle formation
0.66	GO:0031627	telomeric loop formation
0.65	GO:1904354	negative regulation of telomere capping
0.65	GO:2000773	negative regulation of cellular senescence

0.82	GO:0042162	telomeric DNA binding
0.74	GO:0042803	protein homodimerization activity
0.63	GO:0003720	telomerase activity
0.63	GO:0098847	sequence-specific single stranded DNA binding
0.61	GO:0008022	protein C-terminus binding
0.55	GO:0003690	double-stranded DNA binding
0.54	GO:0044877	macromolecular complex binding
0.54	GO:0019899	enzyme binding
0.40	GO:0071532	ankyrin repeat binding
0.39	GO:0008301	DNA binding, bending

0.81	GO:0000784	nuclear chromosome, telomeric region
0.63	GO:0000782	telomere cap complex
0.61	GO:0030870	Mre11 complex
0.59	GO:0016604	nuclear body
0.42	GO:0001673	male germ cell nucleus
0.42	GO:1904115	axon cytoplasm
0.38	GO:0001650	fibrillar center
0.34	GO:0005819	spindle
0.30	GO:0016020	membrane

0.63