Queries 7001 to 8000

GO:0008168

sp|P55347|PKNX1_HUMAN
Homeobox protein PKNOX1
Search

PKNOX1

0.97	Homeobox-containing protein PKNOX1

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0030218	erythrocyte differentiation
0.55	GO:0030217	T cell differentiation
0.54	GO:0001525	angiogenesis
0.54	GO:0043010	camera-type eye development
0.51	GO:0006366	transcription by RNA polymerase II
0.50	GO:0051254	positive regulation of RNA metabolic process
0.50	GO:0010557	positive regulation of macromolecule biosynthetic process

0.56	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.55	GO:0003677	DNA binding
0.54	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.51	GO:0046982	protein heterodimerization activity
0.35	GO:0003785	actin monomer binding
0.35	GO:0051015	actin filament binding
0.34	GO:0001067	regulatory region nucleic acid binding

0.61	GO:0005634	nucleus
0.51	GO:0005667	transcription factor complex
0.39	GO:0005737	cytoplasm
0.34	GO:0015629	actin cytoskeleton
0.34	GO:0043233	organelle lumen
0.34	GO:0015630	microtubule cytoskeleton
0.34	GO:0045271	respiratory chain complex I
0.34	GO:0045171	intercellular bridge
0.34	GO:0044446	intracellular organelle part
0.33	GO:1990204	oxidoreductase complex

sp|P55735|SEC13_HUMAN
Protein SEC13 homolog
Search

SEC13

0.97	SEC13 homolog, nuclear pore and COPII coat complex component

0.84	GO:1904263	positive regulation of TORC1 signaling
0.83	GO:0090114	COPII-coated vesicle budding
0.65	GO:0015031	protein transport
0.56	GO:0035459	cargo loading into vesicle
0.54	GO:0051668	localization within membrane
0.46	GO:0070278	extracellular matrix constituent secretion
0.45	GO:0010842	retina layer formation
0.44	GO:0042462	eye photoreceptor cell development
0.44	GO:0001889	liver development
0.43	GO:0051216	cartilage development

0.62	GO:0005198	structural molecule activity
0.49	GO:0042802	identical protein binding

0.80	GO:0030127	COPII vesicle coat
0.74	GO:0000139	Golgi membrane
0.55	GO:0061700	GATOR2 complex
0.54	GO:0031080	nuclear pore outer ring
0.53	GO:0005765	lysosomal membrane
0.51	GO:0000776	kinetochore
0.48	GO:0005654	nucleoplasm
0.44	GO:0070971	endoplasmic reticulum exit site
0.37	GO:0005789	endoplasmic reticulum membrane
0.36	GO:0070062	extracellular exosome

sp|P55769|NH2L1_HUMAN
NHP2-like protein 1
Search

SNU13

0.97	Small nuclear ribonucleoprotein 13

0.67	GO:0042254	ribosome biogenesis
0.51	GO:0000492	box C/D snoRNP assembly
0.49	GO:0007338	single fertilization
0.45	GO:0008380	RNA splicing
0.43	GO:0006397	mRNA processing
0.42	GO:0016072	rRNA metabolic process
0.41	GO:0034470	ncRNA processing
0.40	GO:0043043	peptide biosynthetic process
0.39	GO:0044267	cellular protein metabolic process
0.38	GO:0034645	cellular macromolecule biosynthetic process

0.59	GO:0003723	RNA binding
0.50	GO:0051117	ATPase binding
0.34	GO:0003735	structural constituent of ribosome
0.34	GO:0019888	protein phosphatase regulator activity
0.32	GO:0016787	hydrolase activity

0.73	GO:0005730	nucleolus
0.61	GO:0030529	intracellular ribonucleoprotein complex
0.45	GO:0120114	Sm-like protein family complex
0.43	GO:0044445	cytosolic part
0.41	GO:0043234	protein complex
0.34	GO:0000159	protein phosphatase type 2A complex
0.33	GO:0005654	nucleoplasm
0.33	GO:0019013	viral nucleocapsid
0.32	GO:0005886	plasma membrane

0.32

GO:0016787

sp|P55771|PAX9_HUMAN
Paired box protein Pax-9
Search

PAX9

0.93	Paired box transcription factor

0.75	GO:0009887	animal organ morphogenesis
0.59	GO:0042481	regulation of odontogenesis
0.59	GO:0060325	face morphogenesis
0.57	GO:0007492	endoderm development
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.54	GO:0071363	cellular response to growth factor stimulus
0.52	GO:1902680	positive regulation of RNA biosynthetic process

0.60	GO:0003700	DNA binding transcription factor activity
0.54	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.35	GO:0005310	dicarboxylic acid transmembrane transporter activity
0.34	GO:0000987	proximal promoter sequence-specific DNA binding
0.33	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.35	GO:0005667	transcription factor complex
0.33	GO:0005743	mitochondrial inner membrane
0.30	GO:0016021	integral component of membrane

sp|P55773|CCL23_HUMAN
C-C motif chemokine 23
Search

0.61	C-C motif chemokine

0.82	GO:0060326	cell chemotaxis
0.74	GO:0006955	immune response
0.72	GO:0010469	regulation of receptor activity
0.59	GO:0097529	myeloid leukocyte migration
0.58	GO:0071674	mononuclear cell migration
0.58	GO:2001263	regulation of C-C chemokine binding
0.58	GO:0072676	lymphocyte migration
0.56	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.55	GO:0071347	cellular response to interleukin-1
0.54	GO:0006954	inflammatory response

0.84	GO:0008009	chemokine activity
0.63	GO:0048020	CCR chemokine receptor binding
0.50	GO:0004698	calcium-dependent protein kinase C activity
0.49	GO:0042056	chemoattractant activity
0.48	GO:0016004	phospholipase activator activity
0.44	GO:0008201	heparin binding
0.37	GO:0042802	identical protein binding
0.35	GO:0045236	CXCR chemokine receptor binding
0.33	GO:0003735	structural constituent of ribosome

0.71	GO:0005615	extracellular space
0.42	GO:0005829	cytosol
0.34	GO:0015934	large ribosomal subunit
0.33	GO:0043234	protein complex

0.50

GO:0004698

sp|P55774|CCL18_HUMAN
C-C motif chemokine 18
Search

0.68	C-C motif chemokine

0.82	GO:0060326	cell chemotaxis
0.74	GO:0006955	immune response
0.74	GO:0010469	regulation of receptor activity
0.63	GO:0071674	mononuclear cell migration
0.63	GO:0097529	myeloid leukocyte migration
0.62	GO:0072676	lymphocyte migration
0.60	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.59	GO:0006954	inflammatory response
0.58	GO:0071347	cellular response to interleukin-1
0.58	GO:0043615	astrocyte cell migration

0.84	GO:0008009	chemokine activity
0.59	GO:0048020	CCR chemokine receptor binding
0.55	GO:0004698	calcium-dependent protein kinase C activity
0.53	GO:0016004	phospholipase activator activity
0.52	GO:0042056	chemoattractant activity
0.41	GO:0042802	identical protein binding
0.39	GO:0008201	heparin binding
0.35	GO:0003735	structural constituent of ribosome

0.72	GO:0005615	extracellular space
0.45	GO:0005829	cytosol
0.37	GO:0044299	C-fiber
0.36	GO:0043204	perikaryon
0.36	GO:0043679	axon terminus
0.36	GO:0005791	rough endoplasmic reticulum
0.36	GO:0030139	endocytic vesicle
0.36	GO:0030425	dendrite
0.36	GO:0015934	large ribosomal subunit
0.36	GO:0048471	perinuclear region of cytoplasm

0.55

GO:0004698

sp|P55786|PSA_HUMAN
Puromycin-sensitive aminopeptidase
Search

NPEPPS

0.56	Puromycin-sensitive aminopeptidase

0.59	GO:0006508	proteolysis
0.52	GO:1903955	positive regulation of protein targeting to mitochondrion
0.52	GO:0071456	cellular response to hypoxia
0.45	GO:0043171	peptide catabolic process
0.35	GO:0000209	protein polyubiquitination
0.34	GO:0007601	visual perception
0.34	GO:0007186	G-protein coupled receptor signaling pathway

0.69	GO:0004177	aminopeptidase activity
0.66	GO:0008237	metallopeptidase activity
0.62	GO:0008270	zinc ion binding
0.46	GO:0042277	peptide binding
0.34	GO:0004930	G-protein coupled receptor activity

0.46	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.34	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.69

EC:3.4.11

GO:0004177

sp|P55789|ALR_HUMAN
FAD-linked sulfhydryl oxidase ALR
Search

GFER

0.58	FAD-linked sulfhydryl oxidase ALR

0.52	GO:0055114	oxidation-reduction process
0.51	GO:0001889	liver development
0.41	GO:0007507	heart development
0.38	GO:0010469	regulation of receptor activity
0.36	GO:0072717	cellular response to actinomycin D
0.36	GO:0045953	negative regulation of natural killer cell mediated cytotoxicity
0.36	GO:1903204	negative regulation of oxidative stress-induced neuron death
0.36	GO:0031100	animal organ regeneration
0.35	GO:2000573	positive regulation of DNA biosynthetic process
0.35	GO:0071356	cellular response to tumor necrosis factor

0.84	GO:0016972	thiol oxidase activity
0.51	GO:0015035	protein disulfide oxidoreductase activity
0.48	GO:0050660	flavin adenine dinucleotide binding
0.40	GO:0042803	protein homodimerization activity
0.38	GO:0008083	growth factor activity

0.48	GO:0005829	cytosol
0.47	GO:0005739	mitochondrion
0.39	GO:0031970	organelle envelope lumen
0.36	GO:0005576	extracellular region
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.84

EC:1.8.3.2

GO:0016972

sp|P55795|HNRH2_HUMAN
Heterogeneous nuclear ribonucleoprotein H2
Search

HNRNPH1

0.88	Heterogeneous nuclear ribonucleoprotein H'

0.49	GO:0043484	regulation of RNA splicing
0.38	GO:0008380	RNA splicing
0.37	GO:0006397	mRNA processing
0.36	GO:0071495	cellular response to endogenous stimulus
0.35	GO:0071310	cellular response to organic substance
0.35	GO:0071774	response to fibroblast growth factor
0.35	GO:1901652	response to peptide
0.34	GO:1901699	cellular response to nitrogen compound
0.34	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.34	GO:1901701	cellular response to oxygen-containing compound

0.59	GO:0003723	RNA binding
0.36	GO:0005515	protein binding

0.58	GO:0019013	viral nucleocapsid
0.56	GO:0030529	intracellular ribonucleoprotein complex
0.51	GO:0005654	nucleoplasm
0.50	GO:0005829	cytosol
0.42	GO:1902494	catalytic complex
0.30	GO:0016020	membrane

sp|P55808|XG_HUMAN
Glycoprotein Xg
Search

0.97	Glycoprotein Xg

0.34	GO:0009405	pathogenesis
0.34	GO:0009664	plant-type cell wall organization

0.35	GO:0005544	calcium-dependent phospholipid binding
0.35	GO:0016757	transferase activity, transferring glycosyl groups
0.34	GO:0005509	calcium ion binding
0.34	GO:0005199	structural constituent of cell wall
0.33	GO:0004872	receptor activity

0.49

GO:0005887

integral component of plasma membrane

0.35

EC:2.4

GO:0016757

sp|P55809|SCOT1_HUMAN
Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial
Search

OXCT1

0.69	Succinyl-CoA:3-ketoacid-coenzyme A transferase

0.80	GO:0046952	ketone body catabolic process
0.47	GO:0042182	ketone catabolic process
0.40	GO:0014823	response to activity
0.40	GO:0060612	adipose tissue development
0.40	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus
0.39	GO:0045471	response to ethanol
0.39	GO:0007584	response to nutrient
0.38	GO:0007507	heart development
0.38	GO:0007420	brain development
0.38	GO:0042594	response to starvation

0.76	GO:0008260	3-oxoacid CoA-transferase activity
0.38	GO:0042803	protein homodimerization activity
0.34	GO:0008083	growth factor activity
0.33	GO:0003735	structural constituent of ribosome

0.56	GO:0005739	mitochondrion
0.44	GO:0005654	nucleoplasm
0.35	GO:0031514	motile cilium
0.33	GO:0005576	extracellular region
0.33	GO:0005840	ribosome

0.76

EC:2.8.3.5

GO:0008260

sp|P55822|SH3BG_HUMAN
SH3 domain-binding glutamic acid-rich protein
Search

0.95	SH3 domain-binding glutamic acid-rich protein isoform X1

0.44	GO:0009967	positive regulation of signal transduction
0.42	GO:0006486	protein glycosylation
0.42	GO:0006461	protein complex assembly
0.36	GO:0055114	oxidation-reduction process

0.48	GO:0017124	SH3 domain binding
0.47	GO:0005070	SH3/SH2 adaptor activity
0.44	GO:0008378	galactosyltransferase activity
0.36	GO:0016491	oxidoreductase activity

0.47	GO:0005737	cytoplasm
0.40	GO:0012505	endomembrane system
0.38	GO:0098588	bounding membrane of organelle
0.38	GO:0031984	organelle subcompartment
0.37	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

0.44

GO:0008378

sp|P55851|UCP2_HUMAN
Mitochondrial uncoupling protein 2
Search

UCP2

0.92	Mitochondrial uncoupling protein B

0.76	GO:0006839	mitochondrial transport
0.55	GO:0051881	regulation of mitochondrial membrane potential
0.55	GO:0001666	response to hypoxia
0.52	GO:1990845	adaptive thermogenesis
0.49	GO:0009409	response to cold
0.44	GO:0000303	response to superoxide
0.43	GO:0015992	proton transport
0.42	GO:0032868	response to insulin
0.42	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus
0.41	GO:0007568	aging

0.56	GO:0017077	oxidative phosphorylation uncoupler activity
0.34	GO:0005515	protein binding
0.33	GO:0015078	hydrogen ion transmembrane transporter activity

0.61	GO:0031966	mitochondrial membrane
0.42	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P55854|SUMO3_HUMAN
Small ubiquitin-related modifier 3
Search

0.77	Small ubiquitin-related modifier

0.80	GO:0016925	protein sumoylation
0.42	GO:0043392	negative regulation of DNA binding
0.42	GO:1903052	positive regulation of proteolysis involved in cellular protein catabolic process
0.42	GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process
0.39	GO:0060216	definitive hemopoiesis
0.38	GO:0043009	chordate embryonic development
0.37	GO:1903322	positive regulation of protein modification by small protein conjugation or removal
0.36	GO:0070911	global genome nucleotide-excision repair
0.36	GO:2000058	regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.35	GO:0034504	protein localization to nucleus

0.51	GO:0031386	protein tag
0.43	GO:0019899	enzyme binding
0.43	GO:0001222	transcription corepressor binding
0.38	GO:0019789	SUMO transferase activity
0.35	GO:0046965	retinoid X receptor binding
0.33	GO:0003723	RNA binding

0.60	GO:0005634	nucleus
0.42	GO:0031974	membrane-enclosed lumen
0.39	GO:0044446	intracellular organelle part
0.36	GO:0070062	extracellular exosome
0.34	GO:0005737	cytoplasm
0.33	GO:0005694	chromosome
0.33	GO:0043234	protein complex

sp|P55884|EIF3B_HUMAN
Eukaryotic translation initiation factor 3 subunit B
Search

EIF3B

0.69	Eukaryotic translation initiation factor 3 subunit B

0.72	GO:0001731	formation of translation preinitiation complex
0.72	GO:0006446	regulation of translational initiation
0.57	GO:0075525	viral translational termination-reinitiation
0.57	GO:0075522	IRES-dependent viral translational initiation
0.37	GO:0003313	heart rudiment development
0.36	GO:0014032	neural crest cell development
0.33	GO:0007018	microtubule-based movement
0.33	GO:2001141	regulation of RNA biosynthetic process

0.82	GO:0031369	translation initiation factor binding
0.72	GO:0003743	translation initiation factor activity
0.35	GO:0032947	protein complex scaffold activity
0.33	GO:0003777	microtubule motor activity
0.33	GO:0008017	microtubule binding
0.33	GO:0046872	metal ion binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.77	GO:0005852	eukaryotic translation initiation factor 3 complex
0.72	GO:0016282	eukaryotic 43S preinitiation complex
0.72	GO:0033290	eukaryotic 48S preinitiation complex
0.37	GO:0070062	extracellular exosome
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|P55895|RAG2_HUMAN
V(D)J recombination-activating protein 2
Search

RAG2

0.50	Recombination activating protein 2

0.65	GO:0006310	DNA recombination
0.57	GO:0002358	B cell homeostatic proliferation
0.56	GO:0002326	B cell lineage commitment
0.56	GO:0002331	pre-B cell allelic exclusion
0.55	GO:0002360	T cell lineage commitment
0.54	GO:0033077	T cell differentiation in thymus
0.53	GO:0046622	positive regulation of organ growth
0.50	GO:0042742	defense response to bacterium
0.50	GO:0002200	somatic diversification of immune receptors
0.48	GO:0016567	protein ubiquitination

0.55	GO:0003677	DNA binding
0.54	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding
0.54	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.53	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding
0.53	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.52	GO:0140034	methylation-dependent protein binding
0.51	GO:0042393	histone binding
0.49	GO:0003682	chromatin binding
0.49	GO:0061630	ubiquitin protein ligase activity
0.44	GO:0008270	zinc ion binding

0.61	GO:0005634	nucleus
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0044446	intracellular organelle part

sp|P55899|FCGRN_HUMAN
IgG receptor FcRn large subunit p51
Search

FCGRT

0.97	Neonatal Fc receptor FcRn alpha chain

0.55	GO:0038094	Fc-gamma receptor signaling pathway
0.41	GO:0002416	IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor
0.36	GO:0006959	humoral immune response

0.67	GO:0019864	IgG binding
0.57	GO:0030881	beta-2-microglobulin binding
0.57	GO:0019770	IgG receptor activity
0.43	GO:0042605	peptide antigen binding
0.37	GO:0005509	calcium ion binding

0.41	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P55916|UCP3_HUMAN
Mitochondrial uncoupling protein 3
Search

UCP3

0.85	Mitochondrial uncoupling protein A

0.77	GO:0006839	mitochondrial transport
0.53	GO:1990845	adaptive thermogenesis
0.52	GO:0001666	response to hypoxia
0.51	GO:0051881	regulation of mitochondrial membrane potential
0.51	GO:0000303	response to superoxide
0.50	GO:0009409	response to cold
0.47	GO:0015992	proton transport
0.46	GO:0006631	fatty acid metabolic process
0.43	GO:0032868	response to insulin
0.43	GO:0007568	aging

0.62	GO:0017077	oxidative phosphorylation uncoupler activity
0.34	GO:0005515	protein binding
0.33	GO:0015078	hydrogen ion transmembrane transporter activity

0.61	GO:0031966	mitochondrial membrane
0.43	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P55957|BID_HUMAN
BH3-interacting domain death agonist
Search

BID

0.97	BH3-interacting domain death agonist

0.79	GO:0043065	positive regulation of apoptotic process
0.64	GO:0032464	positive regulation of protein homooligomerization
0.62	GO:0001836	release of cytochrome c from mitochondria
0.62	GO:0010918	positive regulation of mitochondrial membrane potential
0.62	GO:0097284	hepatocyte apoptotic process
0.62	GO:0097345	mitochondrial outer membrane permeabilization
0.62	GO:2000269	regulation of fibroblast apoptotic process
0.61	GO:0090199	regulation of release of cytochrome c from mitochondria
0.61	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
0.59	GO:0010822	positive regulation of mitochondrion organization

0.56	GO:0031625	ubiquitin protein ligase binding
0.53	GO:0046982	protein heterodimerization activity
0.39	GO:0005123	death receptor binding

0.56	GO:0032592	integral component of mitochondrial membrane
0.52	GO:0005829	cytosol
0.40	GO:0070062	extracellular exosome
0.37	GO:0005741	mitochondrial outer membrane

sp|P56134|ATPK_HUMAN
ATP synthase subunit f, mitochondrial
Search

ATP5J2

0.92	mitochondrial ATP synthase subunit F

0.43	GO:0006754	ATP biosynthetic process
0.40	GO:0015992	proton transport
0.38	GO:0042407	cristae formation
0.37	GO:0006839	mitochondrial transport
0.36	GO:0046907	intracellular transport
0.35	GO:0098662	inorganic cation transmembrane transport
0.33	GO:0006355	regulation of transcription, DNA-templated

0.43	GO:0016887	ATPase activity
0.34	GO:0022857	transmembrane transporter activity
0.33	GO:0003676	nucleic acid binding

0.51	GO:0005753	mitochondrial proton-transporting ATP synthase complex
0.43	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)
0.40	GO:0070062	extracellular exosome
0.36	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.43

GO:0016887

sp|P56159|GFRA1_HUMAN
GDNF family receptor alpha-1
Search

GFRA1

0.97	GDNF family receptor alpha

0.52	GO:0007399	nervous system development
0.37	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.36	GO:0120036	plasma membrane bounded cell projection organization
0.36	GO:0048468	cell development
0.36	GO:0009653	anatomical structure morphogenesis
0.35	GO:0006928	movement of cell or subcellular component
0.35	GO:0008584	male gonad development
0.35	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
0.35	GO:0040011	locomotion
0.35	GO:0001822	kidney development

0.64	GO:0004872	receptor activity
0.36	GO:0005102	receptor binding
0.35	GO:0050839	cell adhesion molecule binding
0.35	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.34	GO:0032403	protein complex binding
0.34	GO:0004871	signal transducer activity

0.68	GO:0031225	anchored component of membrane
0.50	GO:0005886	plasma membrane
0.37	GO:0070062	extracellular exosome
0.36	GO:0019898	extrinsic component of membrane
0.35	GO:0043025	neuronal cell body
0.35	GO:0030424	axon
0.35	GO:0043235	receptor complex
0.35	GO:0009986	cell surface
0.34	GO:0098552	side of membrane
0.33	GO:0098796	membrane protein complex

sp|P56177|DLX1_HUMAN
Homeobox protein DLX-1
Search

DLX1

0.97	Distal-less homeobox 1

0.63	GO:1902871	positive regulation of amacrine cell differentiation
0.63	GO:0021893	cerebral cortex GABAergic interneuron fate commitment
0.63	GO:0021882	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment
0.62	GO:0046533	negative regulation of photoreceptor cell differentiation
0.61	GO:0048715	negative regulation of oligodendrocyte differentiation
0.61	GO:0048706	embryonic skeletal system development
0.60	GO:0021544	subpallium development
0.59	GO:0009954	proximal/distal pattern formation
0.59	GO:0045746	negative regulation of Notch signaling pathway
0.59	GO:0021766	hippocampus development

0.62	GO:0043565	sequence-specific DNA binding
0.54	GO:0001012	RNA polymerase II regulatory region DNA binding
0.54	GO:0003682	chromatin binding
0.52	GO:0003690	double-stranded DNA binding
0.35	GO:0005515	protein binding
0.34	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.33	GO:0008097	5S rRNA binding
0.32	GO:0003735	structural constituent of ribosome

0.60	GO:0005634	nucleus
0.32	GO:0005840	ribosome
0.30	GO:0016020	membrane

sp|P56178|DLX5_HUMAN
Homeobox protein DLX-5
Search

DLX5

0.97	Distal-less homeo box 5

0.63	GO:0060166	olfactory pit development
0.63	GO:0097376	interneuron axon guidance
0.61	GO:0021889	olfactory bulb interneuron differentiation
0.60	GO:0001958	endochondral ossification
0.60	GO:0060325	face morphogenesis
0.58	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
0.58	GO:0060021	palate development
0.58	GO:0001649	osteoblast differentiation
0.58	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.58	GO:0030509	BMP signaling pathway

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0071837	HMG box domain binding
0.57	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.54	GO:0001012	RNA polymerase II regulatory region DNA binding
0.52	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.52	GO:0000785	chromatin
0.49	GO:0031974	membrane-enclosed lumen
0.40	GO:0005737	cytoplasm

sp|P56179|DLX6_HUMAN
Homeobox protein DLX-6
Search

0.97	Distal-less homeobox 6

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.52	GO:0060322	head development
0.52	GO:0009887	animal organ morphogenesis
0.52	GO:0035107	appendage morphogenesis
0.52	GO:0009790	embryo development
0.50	GO:1902871	positive regulation of amacrine cell differentiation
0.49	GO:0046533	negative regulation of photoreceptor cell differentiation
0.49	GO:0060021	palate development

0.63	GO:0043565	sequence-specific DNA binding
0.45	GO:0001012	RNA polymerase II regulatory region DNA binding
0.44	GO:0003682	chromatin binding
0.43	GO:0003690	double-stranded DNA binding
0.34	GO:0008097	5S rRNA binding
0.33	GO:0003700	DNA binding transcription factor activity
0.33	GO:0003735	structural constituent of ribosome
0.33	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.33	GO:0005840	ribosome

sp|P56180|TPTE_HUMAN
Putative tyrosine-protein phosphatase TPTE
Search

0.96	Voltage-sensor containing phosphatase

0.73	GO:0035335	peptidyl-tyrosine dephosphorylation
0.50	GO:0034220	ion transmembrane transport
0.44	GO:0046856	phosphatidylinositol dephosphorylation
0.35	GO:0006661	phosphatidylinositol biosynthetic process
0.34	GO:0007165	signal transduction

0.77	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.74	GO:0004725	protein tyrosine phosphatase activity
0.56	GO:0005216	ion channel activity
0.48	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity
0.37	GO:0051800	phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity
0.32	GO:0003735	structural constituent of ribosome
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0019001	guanyl nucleotide binding
0.31	GO:0032555	purine ribonucleotide binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.39	GO:0005794	Golgi apparatus
0.36	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0098588	bounding membrane of organelle
0.33	GO:0005763	mitochondrial small ribosomal subunit
0.30	GO:0016021	integral component of membrane

0.77

GO:0008138

sp|P56181|NDUV3_HUMAN
NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial
Search

NDUFV3

0.95	NADH dehydrogenase flavoprotein 3, mitochondrial

0.44	GO:0042775	mitochondrial ATP synthesis coupled electron transport
0.38	GO:0032981	mitochondrial respiratory chain complex I assembly
0.33	GO:0007165	signal transduction

0.36	GO:0008137	NADH dehydrogenase (ubiquinone) activity
0.35	GO:0003723	RNA binding
0.35	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.33	GO:0046872	metal ion binding

0.82	GO:0005747	mitochondrial respiratory chain complex I
0.43	GO:0005654	nucleoplasm

0.36

EC:1.6.5.3

GO:0008137

sp|P56182|RRP1_HUMAN
Ribosomal RNA processing protein 1 homolog A
Search

RRP1

0.90	Ribosomal RNA processing protein 1 like protein A

0.69	GO:0006364	rRNA processing
0.48	GO:0043923	positive regulation by host of viral transcription
0.46	GO:0098586	cellular response to virus
0.45	GO:0010923	negative regulation of phosphatase activity
0.44	GO:0043065	positive regulation of apoptotic process
0.43	GO:0006366	transcription by RNA polymerase II
0.43	GO:0045944	positive regulation of transcription by RNA polymerase II
0.42	GO:0034260	negative regulation of GTPase activity
0.40	GO:0043484	regulation of RNA splicing
0.35	GO:0006915	apoptotic process

0.46	GO:0001105	RNA polymerase II transcription coactivator activity
0.35	GO:0003723	RNA binding
0.34	GO:0008478	pyridoxal kinase activity
0.34	GO:0005515	protein binding

0.83	GO:0030688	preribosome, small subunit precursor
0.51	GO:0005730	nucleolus
0.47	GO:0030687	preribosome, large subunit precursor
0.41	GO:0000791	euchromatin
0.40	GO:0000792	heterochromatin
0.34	GO:0005654	nucleoplasm
0.33	GO:0005829	cytosol

0.34

EC:2.7.1.35

GO:0008478

sp|P56192|SYMC_HUMAN
Methionine--tRNA ligase, cytoplasmic
Search

MARS

0.61	Methionine-tRNA synthetase

0.78	GO:0006431	methionyl-tRNA aminoacylation
0.58	GO:1901838	positive regulation of transcription of nucleolar large rRNA by RNA polymerase I
0.57	GO:0036120	cellular response to platelet-derived growth factor stimulus
0.57	GO:0071364	cellular response to epidermal growth factor stimulus
0.56	GO:0009303	rRNA transcription
0.55	GO:0032869	cellular response to insulin stimulus
0.52	GO:0009267	cellular response to starvation
0.33	GO:0007017	microtubule-based process

0.78	GO:0004825	methionine-tRNA ligase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0000049	tRNA binding
0.33	GO:0005515	protein binding

0.57	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex
0.50	GO:0005829	cytosol
0.50	GO:0005730	nucleolus
0.37	GO:0070062	extracellular exosome
0.34	GO:0005739	mitochondrion
0.34	GO:0005869	dynactin complex
0.30	GO:0016020	membrane

0.78

EC:6.1.1.10

GO:0004825

sp|P56199|ITA1_HUMAN
Integrin alpha-1
Search

ITGA1

0.97	Laminin and collagen receptor

0.79	GO:0007229	integrin-mediated signaling pathway
0.72	GO:0007155	cell adhesion
0.60	GO:0032516	positive regulation of phosphoprotein phosphatase activity
0.59	GO:0045123	cellular extravasation
0.59	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway
0.58	GO:0030593	neutrophil chemotaxis
0.55	GO:0008285	negative regulation of cell proliferation
0.40	GO:0043525	positive regulation of neuron apoptotic process
0.40	GO:0042311	vasodilation
0.40	GO:0000187	activation of MAPK activity

0.62	GO:0098639	collagen binding involved in cell-matrix adhesion
0.57	GO:0019903	protein phosphatase binding
0.38	GO:0038064	collagen receptor activity
0.38	GO:0005102	receptor binding
0.35	GO:0046872	metal ion binding
0.32	GO:0008168	methyltransferase activity
0.31	GO:0003676	nucleic acid binding

0.81	GO:0008305	integrin complex
0.58	GO:0045178	basal part of cell
0.57	GO:0005925	focal adhesion
0.56	GO:0009897	external side of plasma membrane
0.40	GO:0043204	perikaryon
0.40	GO:0001669	acrosomal vesicle
0.39	GO:0045121	membrane raft
0.38	GO:0043005	neuron projection
0.37	GO:0070062	extracellular exosome
0.35	GO:0005581	collagen trimer

0.32

GO:0008168

sp|P56202|CATW_HUMAN
Cathepsin W
Search

CTSW

0.97	Cathepsin W

0.61	GO:0006508	proteolysis
0.48	GO:0044257	cellular protein catabolic process
0.39	GO:0002576	platelet degranulation
0.37	GO:0006955	immune response
0.33	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.33	GO:2001235	positive regulation of apoptotic signaling pathway
0.32	GO:0032504	multicellular organism reproduction

0.72	GO:0008234	cysteine-type peptidase activity
0.48	GO:0004175	endopeptidase activity
0.33	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process
0.32	GO:0004177	aminopeptidase activity

0.51	GO:0005764	lysosome
0.49	GO:0005615	extracellular space
0.39	GO:0031089	platelet dense granule lumen
0.34	GO:1903561	extracellular vesicle
0.30	GO:0031224	intrinsic component of membrane

0.72

GO:0008234

sp|P56211|ARP19_HUMAN
cAMP-regulated phosphoprotein 19
Search

ARPP19

0.94	LOW QUALITY PROTEIN: cAMP-regulated phosphoprotein 19

0.83	GO:0032515	negative regulation of phosphoprotein phosphatase activity
0.67	GO:0051301	cell division
0.67	GO:0007049	cell cycle
0.45	GO:0050796	regulation of insulin secretion
0.39	GO:0045722	positive regulation of gluconeogenesis
0.36	GO:0046579	positive regulation of Ras protein signal transduction
0.36	GO:0007212	dopamine receptor signaling pathway
0.35	GO:0009749	response to glucose
0.35	GO:0046326	positive regulation of glucose import
0.34	GO:0007584	response to nutrient

0.83	GO:0004864	protein phosphatase inhibitor activity
0.48	GO:0015459	potassium channel regulator activity
0.46	GO:0051721	protein phosphatase 2A binding
0.45	GO:0008200	ion channel inhibitor activity
0.44	GO:0005102	receptor binding
0.34	GO:0019901	protein kinase binding
0.33	GO:0051015	actin filament binding
0.33	GO:0003777	microtubule motor activity
0.33	GO:0008017	microtubule binding
0.32	GO:0032559	adenyl ribonucleotide binding

0.49	GO:0005737	cytoplasm
0.35	GO:0005654	nucleoplasm
0.33	GO:0016459	myosin complex

sp|P56270|MAZ_HUMAN
Myc-associated zinc finger protein
Search

MAZ

0.94	MYC-associated zinc finger protein a (purine-binding transcription factor)

0.52	GO:0006369	termination of RNA polymerase II transcription
0.50	GO:0006367	transcription initiation from RNA polymerase II promoter
0.44	GO:0045944	positive regulation of transcription by RNA polymerase II
0.41	GO:0001885	endothelial cell development
0.40	GO:0048731	system development
0.38	GO:0048646	anatomical structure formation involved in morphogenesis
0.37	GO:0060322	head development
0.36	GO:0009607	response to biotic stimulus
0.36	GO:0007018	microtubule-based movement
0.34	GO:0006968	cellular defense response

0.53	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding
0.42	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.40	GO:0003682	chromatin binding
0.37	GO:0005515	protein binding
0.37	GO:0003723	RNA binding
0.36	GO:0003777	microtubule motor activity
0.35	GO:0046872	metal ion binding
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0008144	drug binding

0.40	GO:0005634	nucleus
0.37	GO:0043233	organelle lumen
0.36	GO:0044446	intracellular organelle part
0.35	GO:0099512	supramolecular fiber
0.35	GO:0015630	microtubule cytoskeleton
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:2.7.8

GO:0016780

sp|P56277|CMC4_HUMAN
Cx9C motif-containing protein 4
Search

CMC4

0.97	Mature T-cell proliferation 1 neighbor

0.40

GO:0008283

cell proliferation

0.61	GO:0005739	mitochondrion
0.58	GO:0031970	organelle envelope lumen

sp|P56278|MTCP1_HUMAN
Protein p13 MTCP-1
Search

MTCP1

0.97	Mature T-cell proliferation 1

0.85	GO:0033138	positive regulation of peptidyl-serine phosphorylation
0.80	GO:0071902	positive regulation of protein serine/threonine kinase activity
0.55	GO:0010918	positive regulation of mitochondrial membrane potential
0.54	GO:0032461	positive regulation of protein oligomerization
0.54	GO:0070207	protein homotrimerization
0.52	GO:0071356	cellular response to tumor necrosis factor
0.50	GO:0008284	positive regulation of cell proliferation
0.50	GO:0043066	negative regulation of apoptotic process
0.40	GO:2000036	regulation of stem cell population maintenance
0.39	GO:0008283	cell proliferation

0.85	GO:0043539	protein serine/threonine kinase activator activity
0.78	GO:0019901	protein kinase binding
0.48	GO:0042802	identical protein binding

0.60	GO:0043234	protein complex
0.58	GO:0005739	mitochondrion
0.40	GO:0045120	pronucleus
0.39	GO:0031970	organelle envelope lumen
0.38	GO:0005938	cell cortex
0.37	GO:0005783	endoplasmic reticulum

sp|P56279|TCL1A_HUMAN
T-cell leukemia/lymphoma protein 1A
Search

MTCP1

0.97	Mature T-cell proliferation 1

0.85	GO:0033138	positive regulation of peptidyl-serine phosphorylation
0.80	GO:0071902	positive regulation of protein serine/threonine kinase activity
0.76	GO:0010918	positive regulation of mitochondrial membrane potential
0.75	GO:0032461	positive regulation of protein oligomerization
0.74	GO:0070207	protein homotrimerization
0.71	GO:0071356	cellular response to tumor necrosis factor
0.67	GO:0008284	positive regulation of cell proliferation
0.66	GO:0043066	negative regulation of apoptotic process
0.43	GO:2000036	regulation of stem cell population maintenance
0.42	GO:0019827	stem cell population maintenance

0.85	GO:0043539	protein serine/threonine kinase activator activity
0.78	GO:0019901	protein kinase binding
0.63	GO:0042802	identical protein binding

0.60	GO:0043234	protein complex
0.50	GO:0005739	mitochondrion
0.43	GO:0045120	pronucleus
0.41	GO:0005783	endoplasmic reticulum
0.40	GO:0005938	cell cortex
0.37	GO:0031970	organelle envelope lumen

sp|P56282|DPOE2_HUMAN
DNA polymerase epsilon subunit 2
Search

POLE2

0.83	DNA polymerase epsilon subunit

0.67	GO:0071897	DNA biosynthetic process
0.67	GO:0006261	DNA-dependent DNA replication
0.49	GO:0006301	postreplication repair
0.35	GO:0000082	G1/S transition of mitotic cell cycle
0.35	GO:0000723	telomere maintenance
0.34	GO:0019725	cellular homeostasis
0.33	GO:0060285	cilium-dependent cell motility
0.33	GO:0070286	axonemal dynein complex assembly

0.71	GO:0003887	DNA-directed DNA polymerase activity
0.55	GO:0003677	DNA binding
0.33	GO:0005515	protein binding

0.79	GO:0008622	epsilon DNA polymerase complex
0.52	GO:0016604	nuclear body
0.34	GO:0005680	anaphase-promoting complex
0.31	GO:0005737	cytoplasm

0.71

GO:0003887

sp|P56373|P2RX3_HUMAN
P2X purinoceptor 3
Search

0.85	GO:0033198	response to ATP
0.85	GO:0035590	purinergic nucleotide receptor signaling pathway
0.80	GO:0060079	excitatory postsynaptic potential
0.61	GO:0098655	cation transmembrane transport
0.60	GO:0030432	peristalsis
0.60	GO:0014832	urinary bladder smooth muscle contraction
0.60	GO:0048266	behavioral response to pain
0.58	GO:0007274	neuromuscular synaptic transmission
0.57	GO:0048167	regulation of synaptic plasticity
0.56	GO:0009612	response to mechanical stimulus

0.85	GO:0004931	extracellularly ATP-gated cation channel activity
0.85	GO:0001614	purinergic nucleotide receptor activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.38	GO:0019103	pyrimidine nucleotide binding
0.37	GO:0099604	ligand-gated calcium channel activity
0.37	GO:0045296	cadherin binding
0.34	GO:0042802	identical protein binding

0.78	GO:0098794	postsynapse
0.67	GO:0005887	integral component of plasma membrane
0.55	GO:0030424	axon
0.54	GO:0043235	receptor complex
0.50	GO:0005639	integral component of nuclear inner membrane
0.40	GO:0044309	neuron spine
0.40	GO:0043679	axon terminus
0.39	GO:0043025	neuronal cell body
0.39	GO:0030425	dendrite
0.39	GO:0005791	rough endoplasmic reticulum

sp|P56377|AP1S2_HUMAN
AP-1 complex subunit sigma-2
Search

AP1S2

0.57	AP complex subunit sigma

0.69	GO:0006886	intracellular protein transport
0.68	GO:0016192	vesicle-mediated transport
0.38	GO:0060612	adipose tissue development
0.38	GO:0008542	visual learning
0.37	GO:0036465	synaptic vesicle recycling
0.37	GO:0050885	neuromuscular process controlling balance
0.37	GO:0045444	fat cell differentiation
0.35	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.33	GO:0050690	regulation of defense response to virus by virus

0.70	GO:0008565	protein transporter activity
0.34	GO:0005515	protein binding

0.75	GO:0030117	membrane coat
0.37	GO:0005905	clathrin-coated pit
0.36	GO:0098793	presynapse
0.36	GO:0005794	Golgi apparatus
0.36	GO:0030659	cytoplasmic vesicle membrane
0.34	GO:0005765	lysosomal membrane
0.33	GO:0005829	cytosol
0.33	GO:0031984	organelle subcompartment

sp|P56378|68MP_HUMAN
6.8 kDa mitochondrial proteolipid
Search

0.97	6.8 kDa mitochondrial proteolipid

0.36	GO:0006915	apoptotic process
0.36	GO:0045786	negative regulation of cell cycle

0.36

GO:0008134

transcription factor binding

0.61	GO:0005739	mitochondrion
0.41	GO:0045259	proton-transporting ATP synthase complex
0.39	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P56381|ATP5E_HUMAN
ATP synthase subunit epsilon, mitochondrial
Search

ATP5E

0.88	ATP synthase subunit epsilonserine-threonine

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.69	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.38	GO:0042407	cristae formation
0.37	GO:0006839	mitochondrial transport
0.36	GO:0046907	intracellular transport

0.72	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism
0.37	GO:0008553	proton-exporting ATPase activity, phosphorylative mechanism

0.84	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)
0.36	GO:0005759	mitochondrial matrix

0.37

EC:3.6.3.6

GO:0008553

sp|P56385|ATP5I_HUMAN
ATP synthase subunit e, mitochondrial
Search

ATP5I

0.82	Mitochondrial ATP synthase subunit e

0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.37	GO:0042407	cristae formation
0.36	GO:0006839	mitochondrial transport
0.35	GO:0001666	response to hypoxia
0.35	GO:0046907	intracellular transport
0.35	GO:0032570	response to progesterone
0.35	GO:0043627	response to estrogen

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.47	GO:0016887	ATPase activity
0.39	GO:0033142	progesterone receptor binding
0.37	GO:0031490	chromatin DNA binding
0.37	GO:0047624	adenosine-tetraphosphatase activity

0.78	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
0.36	GO:0000790	nuclear chromatin
0.36	GO:0032993	protein-DNA complex
0.34	GO:0016363	nuclear matrix
0.30	GO:0016021	integral component of membrane

0.47

GO:0016887

sp|P56470|LEG4_HUMAN
Galectin-4
Search

LGALS4

0.58

Galectin

0.36	GO:0007155	cell adhesion
0.33	GO:0008039	synaptic target recognition
0.32	GO:0006511	ubiquitin-dependent protein catabolic process

0.70	GO:0030246	carbohydrate binding
0.66	GO:0016936	galactoside binding
0.34	GO:0005515	protein binding

0.54	GO:0005615	extracellular space
0.36	GO:0005829	cytosol
0.34	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|P56524|HDAC4_HUMAN
Histone deacetylase 4
Search

HDAC4

0.51	Histone deacetylase

0.80	GO:0016575	histone deacetylation
0.55	GO:0014894	response to denervation involved in regulation of muscle adaptation
0.55	GO:0034983	peptidyl-lysine deacetylation
0.55	GO:0010832	negative regulation of myotube differentiation
0.55	GO:0033235	positive regulation of protein sumoylation
0.55	GO:0045820	negative regulation of glycolytic process
0.54	GO:0001501	skeletal system development
0.54	GO:0048742	regulation of skeletal muscle fiber development
0.54	GO:1902894	negative regulation of pri-miRNA transcription by RNA polymerase II
0.54	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling

0.81	GO:0004407	histone deacetylase activity
0.73	GO:0034979	NAD-dependent protein deacetylase activity
0.53	GO:0046872	metal ion binding
0.53	GO:0070491	repressing transcription factor binding
0.53	GO:0033613	activating transcription factor binding
0.52	GO:0042826	histone deacetylase binding
0.52	GO:0001085	RNA polymerase II transcription factor binding
0.52	GO:0001047	core promoter binding
0.51	GO:0003714	transcription corepressor activity
0.49	GO:0019901	protein kinase binding

0.81	GO:0000118	histone deacetylase complex
0.52	GO:0042641	actomyosin
0.52	GO:0031594	neuromuscular junction
0.51	GO:0017053	transcriptional repressor complex
0.46	GO:0005829	cytosol
0.39	GO:0031672	A band
0.39	GO:0030018	Z disc
0.35	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

0.81

EC:3.5.1.98

GO:0004407

sp|P56537|IF6_HUMAN
Eukaryotic translation initiation factor 6
Search

EIF6

0.68	Eukaryotic translation initiation factor 6

0.78	GO:0042256	mature ribosome assembly
0.72	GO:0042273	ribosomal large subunit biogenesis
0.71	GO:0006413	translational initiation
0.62	GO:0000054	ribosomal subunit export from nucleus
0.56	GO:0045652	regulation of megakaryocyte differentiation
0.55	GO:0006110	regulation of glycolytic process
0.54	GO:0042304	regulation of fatty acid biosynthetic process
0.53	GO:0032868	response to insulin
0.53	GO:2000377	regulation of reactive oxygen species metabolic process
0.51	GO:0045727	positive regulation of translation

0.74	GO:0043022	ribosome binding
0.74	GO:0043023	ribosomal large subunit binding
0.72	GO:0003743	translation initiation factor activity
0.33	GO:0005515	protein binding
0.32	GO:0016787	hydrolase activity

0.69	GO:0005730	nucleolus
0.56	GO:0005638	lamin filament
0.47	GO:0005737	cytoplasm
0.46	GO:0030687	preribosome, large subunit precursor
0.38	GO:0005654	nucleoplasm
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.32

GO:0016787

sp|P56539|CAV3_HUMAN
Caveolin-3
Search

CAV3

0.85

Caveolin

0.85	GO:0070836	caveola assembly
0.77	GO:0046716	muscle cell cellular homeostasis
0.67	GO:0023051	regulation of signaling
0.63	GO:0051001	negative regulation of nitric-oxide synthase activity
0.62	GO:0098901	regulation of cardiac muscle cell action potential
0.62	GO:0031623	receptor internalization
0.61	GO:0060306	regulation of membrane repolarization
0.61	GO:0086004	regulation of cardiac muscle cell contraction
0.61	GO:1903844	regulation of cellular response to transforming growth factor beta stimulus
0.60	GO:0014706	striated muscle tissue development

0.79	GO:0044325	ion channel binding
0.75	GO:0032947	protein complex scaffold activity
0.58	GO:0099106	ion channel regulator activity
0.57	GO:0071253	connexin binding
0.55	GO:0043014	alpha-tubulin binding
0.55	GO:0017080	sodium channel regulator activity
0.53	GO:0008022	protein C-terminus binding
0.52	GO:0050998	nitric-oxide synthase binding
0.50	GO:0032403	protein complex binding
0.49	GO:0016248	channel inhibitor activity

0.84	GO:0005901	caveola
0.74	GO:0000139	Golgi membrane
0.58	GO:0042383	sarcolemma
0.53	GO:0016010	dystrophin-associated glycoprotein complex
0.52	GO:0005783	endoplasmic reticulum
0.48	GO:0002080	acrosomal membrane
0.47	GO:0005925	focal adhesion
0.46	GO:0005768	endosome
0.46	GO:0048471	perinuclear region of cytoplasm
0.44	GO:0005929	cilium

sp|P56545|CTBP2_HUMAN
C-terminal-binding protein 2
Search

CTBP2

0.92	C-terminal binding protein 2

0.51	GO:0055114	oxidation-reduction process
0.51	GO:0048386	positive regulation of retinoic acid receptor signaling pathway
0.51	GO:0050872	white fat cell differentiation
0.50	GO:0035563	positive regulation of chromatin binding
0.48	GO:1990823	response to leukemia inhibitory factor
0.46	GO:0071345	cellular response to cytokine stimulus
0.45	GO:0045944	positive regulation of transcription by RNA polymerase II
0.45	GO:1903507	negative regulation of nucleic acid-templated transcription
0.44	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
0.43	GO:0010629	negative regulation of gene expression

0.66	GO:0051287	NAD binding
0.64	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
0.50	GO:0042974	retinoic acid receptor binding
0.48	GO:0003714	transcription corepressor activity
0.46	GO:0003713	transcription coactivator activity
0.46	GO:0003682	chromatin binding
0.45	GO:0019901	protein kinase binding
0.44	GO:0032403	protein complex binding
0.42	GO:0042803	protein homodimerization activity

0.51	GO:0097470	ribbon synapse
0.48	GO:0017053	transcriptional repressor complex
0.41	GO:0005634	nucleus
0.40	GO:0005829	cytosol
0.38	GO:0030054	cell junction

0.64

EC:1.1.1

GO:0016616

sp|P56555|DSCR4_HUMAN
Down syndrome critical region protein 4
Search

DSCR4

0.97	Down syndrome critical region protein 4

sp|P56556|NDUA6_HUMAN
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6
Search

NDUFA6

0.93	NADH dehydrogenase 1 alpha subcomplex subunit 6

0.53	GO:0006979	response to oxidative stress
0.52	GO:0055114	oxidation-reduction process
0.38	GO:0032981	mitochondrial respiratory chain complex I assembly
0.35	GO:0006119	oxidative phosphorylation

0.36

GO:0008137

NADH dehydrogenase (ubiquinone) activity

0.62	GO:0070469	respiratory chain
0.62	GO:0031966	mitochondrial membrane
0.62	GO:0019866	organelle inner membrane
0.58	GO:0030964	NADH dehydrogenase complex
0.55	GO:0098798	mitochondrial protein complex
0.52	GO:1990204	oxidoreductase complex
0.48	GO:0098796	membrane protein complex

0.36

EC:1.6.5.3

GO:0008137

sp|P56557|TM50B_HUMAN
Transmembrane protein 50B
Search

TMEM50B

0.97	HCV p7-trans-regulated protein 3

0.48	GO:0005783	endoplasmic reticulum
0.38	GO:0000139	Golgi membrane
0.37	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|P56559|ARL4C_HUMAN
ADP-ribosylation factor-like protein 4C
Search

ARL4C

0.97	ADP ribosylation factor like GTPase 4C

0.52	GO:0032456	endocytic recycling
0.39	GO:0050873	brown fat cell differentiation
0.34	GO:0016579	protein deubiquitination
0.34	GO:0006511	ubiquitin-dependent protein catabolic process

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0043014	alpha-tubulin binding
0.34	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.33	GO:0003924	GTPase activity
0.32	GO:0003676	nucleic acid binding

0.47	GO:0005829	cytosol
0.41	GO:0005886	plasma membrane
0.38	GO:0005730	nucleolus
0.38	GO:0005654	nucleoplasm
0.36	GO:0030175	filopodium
0.30	GO:0016021	integral component of membrane

0.34

EC:3.4.19.12

GO:0036459

sp|P56589|PEX3_HUMAN
Peroxisomal biogenesis factor 3
Search

PEX3

0.94	Peroxisomal biogenesis factor 3

0.78	GO:0007031	peroxisome organization
0.56	GO:0015919	peroxisomal membrane transport
0.52	GO:0006612	protein targeting to membrane
0.52	GO:0017038	protein import
0.51	GO:0072594	establishment of protein localization to organelle
0.37	GO:0044091	membrane biogenesis
0.33	GO:0055085	transmembrane transport

0.51	GO:0008289	lipid binding
0.49	GO:0046983	protein dimerization activity

0.79	GO:0005779	integral component of peroxisomal membrane
0.57	GO:0032994	protein-lipid complex
0.50	GO:0005783	endoplasmic reticulum
0.49	GO:0005654	nucleoplasm
0.44	GO:0043234	protein complex
0.36	GO:0005829	cytosol
0.34	GO:0005887	integral component of plasma membrane

sp|P56597|NDK5_HUMAN
Nucleoside diphosphate kinase homolog 5
Search

NME5

0.86	Nucleoside diphosphate kinase like protein 5

0.78	GO:0006228	UTP biosynthetic process
0.78	GO:0006183	GTP biosynthetic process
0.75	GO:0046036	CTP metabolic process
0.70	GO:0006165	nucleoside diphosphate phosphorylation
0.69	GO:0048515	spermatid differentiation
0.62	GO:1902176	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
0.59	GO:0003351	epithelial cilium movement
0.58	GO:0021591	ventricular system development
0.54	GO:0007281	germ cell development
0.54	GO:0060271	cilium assembly

0.78	GO:0004550	nucleoside diphosphate kinase activity
0.34	GO:0004430	1-phosphatidylinositol 4-kinase activity
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding
0.32	GO:0046872	metal ion binding

0.57	GO:0036126	sperm flagellum
0.36	GO:0005622	intracellular
0.35	GO:1902493	acetyltransferase complex
0.34	GO:0043233	organelle lumen
0.34	GO:1904949	ATPase complex
0.33	GO:0043234	protein complex
0.33	GO:0043228	non-membrane-bounded organelle
0.33	GO:0043227	membrane-bounded organelle
0.30	GO:0016020	membrane

0.78	EC:2.7.4.6	GO:0004550
0.34	KEGG:R03361	GO:0004430

sp|P56645|PER3_HUMAN
Period circadian protein homolog 3
Search

PER3

0.92	Period circadian protein like protein 2

0.84	GO:0032922	circadian regulation of gene expression
0.56	GO:0045187	regulation of circadian sleep/wake cycle, sleep
0.52	GO:0050821	protein stabilization
0.51	GO:0000122	negative regulation of transcription by RNA polymerase II
0.51	GO:0009648	photoperiodism
0.36	GO:0006351	transcription, DNA-templated

0.51	GO:0031625	ubiquitin protein ligase binding
0.50	GO:0019900	kinase binding

0.46	GO:0005634	nucleus
0.39	GO:0005737	cytoplasm

sp|P56693|SOX10_HUMAN
Transcription factor SOX-10
Search

SOX10

0.97	LOW QUALITY PROTEIN: transcription factor SOX-10

0.58	GO:0030318	melanocyte differentiation
0.57	GO:0032808	lacrimal gland development
0.57	GO:0022010	central nervous system myelination
0.57	GO:0048484	enteric nervous system development
0.56	GO:0001755	neural crest cell migration
0.56	GO:0002052	positive regulation of neuroblast proliferation
0.55	GO:0014015	positive regulation of gliogenesis
0.55	GO:0007422	peripheral nervous system development
0.54	GO:0048546	digestive tract morphogenesis
0.54	GO:0090090	negative regulation of canonical Wnt signaling pathway

0.55	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.55	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.54	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.52	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.51	GO:0003682	chromatin binding
0.49	GO:0042802	identical protein binding
0.49	GO:0008134	transcription factor binding
0.35	GO:0003713	transcription coactivator activity
0.35	GO:0019899	enzyme binding

0.60	GO:0005634	nucleus
0.57	GO:0031315	extrinsic component of mitochondrial outer membrane
0.46	GO:0070013	intracellular organelle lumen
0.38	GO:0000785	chromatin

sp|P56696|KCNQ4_HUMAN
Potassium voltage-gated channel subfamily KQT member 4
Search

KCNQ4

0.90	Potassium voltage-gated channel subfamily KQT member 4

0.73	GO:0071805	potassium ion transmembrane transport
0.57	GO:0042472	inner ear morphogenesis
0.56	GO:0007605	sensory perception of sound
0.39	GO:0034765	regulation of ion transmembrane transport
0.35	GO:0010466	negative regulation of peptidase activity
0.34	GO:0006955	immune response
0.34	GO:0006898	receptor-mediated endocytosis
0.34	GO:0032227	negative regulation of synaptic transmission, dopaminergic
0.33	GO:0006508	proteolysis

0.77	GO:0005249	voltage-gated potassium channel activity
0.35	GO:0005044	scavenger receptor activity
0.35	GO:0001871	pattern binding
0.35	GO:0030414	peptidase inhibitor activity
0.34	GO:0005515	protein binding
0.34	GO:0008234	cysteine-type peptidase activity
0.34	GO:0030246	carbohydrate binding

0.77	GO:0008076	voltage-gated potassium channel complex
0.40	GO:0009925	basal plasma membrane
0.36	GO:0030118	clathrin coat
0.33	GO:0043005	neuron projection

0.34

GO:0008234

sp|P56703|WNT3_HUMAN
Proto-oncogene Wnt-3
Search

0.77	GO:0016055	Wnt signaling pathway
0.70	GO:0007275	multicellular organism development
0.59	GO:0060322	head development
0.59	GO:0050922	negative regulation of chemotaxis
0.59	GO:0072089	stem cell proliferation
0.59	GO:0007498	mesoderm development
0.58	GO:0001649	osteoblast differentiation
0.58	GO:0010771	negative regulation of cell morphogenesis involved in differentiation
0.57	GO:0061387	regulation of extent of cell growth
0.57	GO:0048640	negative regulation of developmental growth

0.73	GO:0005102	receptor binding
0.53	GO:0030545	receptor regulator activity
0.53	GO:0019904	protein domain specific binding
0.49	GO:0039706	co-receptor binding
0.45	GO:0003713	transcription coactivator activity

0.76	GO:0005578	proteinaceous extracellular matrix
0.49	GO:0005615	extracellular space
0.49	GO:1990851	Wnt-Frizzled-LRP5/6 complex
0.44	GO:0009986	cell surface
0.38	GO:0005788	endoplasmic reticulum lumen
0.37	GO:1990909	Wnt signalosome
0.37	GO:0005796	Golgi lumen
0.36	GO:0098805	whole membrane
0.36	GO:0098588	bounding membrane of organelle
0.36	GO:0030139	endocytic vesicle

sp|P56704|WNT3A_HUMAN
Protein Wnt-3a
Search

0.77	GO:0016055	Wnt signaling pathway
0.70	GO:0007275	multicellular organism development
0.60	GO:0007498	mesoderm development
0.60	GO:0060322	head development
0.60	GO:0050922	negative regulation of chemotaxis
0.59	GO:0072089	stem cell proliferation
0.59	GO:0001649	osteoblast differentiation
0.59	GO:0010771	negative regulation of cell morphogenesis involved in differentiation
0.58	GO:0061387	regulation of extent of cell growth
0.58	GO:0048640	negative regulation of developmental growth

0.73	GO:0005102	receptor binding
0.54	GO:0019904	protein domain specific binding
0.54	GO:0030545	receptor regulator activity
0.52	GO:0039706	co-receptor binding
0.48	GO:0003713	transcription coactivator activity

0.76	GO:0005578	proteinaceous extracellular matrix
0.53	GO:1990851	Wnt-Frizzled-LRP5/6 complex
0.51	GO:0005615	extracellular space
0.46	GO:0009986	cell surface
0.38	GO:0005788	endoplasmic reticulum lumen
0.37	GO:1990909	Wnt signalosome
0.37	GO:0005796	Golgi lumen
0.37	GO:0098805	whole membrane
0.36	GO:0098588	bounding membrane of organelle
0.36	GO:0030139	endocytic vesicle

sp|P56705|WNT4_HUMAN
Protein Wnt-4
Search

0.77	GO:0016055	Wnt signaling pathway
0.70	GO:0007275	multicellular organism development
0.57	GO:2000225	negative regulation of testosterone biosynthetic process
0.57	GO:0031945	positive regulation of glucocorticoid metabolic process
0.57	GO:0061369	negative regulation of testicular blood vessel morphogenesis
0.57	GO:0033079	immature T cell proliferation
0.57	GO:2000019	negative regulation of male gonad development
0.57	GO:0032346	positive regulation of aldosterone metabolic process
0.56	GO:0061184	positive regulation of dermatome development
0.56	GO:0072034	renal vesicle induction

0.73	GO:0005102	receptor binding
0.51	GO:0003714	transcription corepressor activity
0.34	GO:0030545	receptor regulator activity

0.75	GO:0005578	proteinaceous extracellular matrix
0.50	GO:0005615	extracellular space
0.49	GO:0009986	cell surface
0.38	GO:0005737	cytoplasm
0.36	GO:0012505	endomembrane system
0.35	GO:0070013	intracellular organelle lumen
0.35	GO:1903561	extracellular vesicle
0.34	GO:0012506	vesicle membrane
0.34	GO:0043231	intracellular membrane-bounded organelle
0.34	GO:0097708	intracellular vesicle

sp|P56706|WNT7B_HUMAN
Protein Wnt-7b
Search

sp|P56715|RP1_HUMAN
Oxygen-regulated protein 1
Search

RP1

0.96	Oxygen-regulated protein 1

0.83	GO:0042461	photoreceptor cell development
0.76	GO:0007601	visual perception
0.71	GO:0042670	retinal cone cell differentiation
0.68	GO:0045494	photoreceptor cell maintenance
0.68	GO:0035082	axoneme assembly
0.68	GO:1902857	positive regulation of non-motile cilium assembly
0.62	GO:0035556	intracellular signal transduction
0.61	GO:0071482	cellular response to light stimulus
0.41	GO:0007603	phototransduction, visible light
0.41	GO:0098869	cellular oxidant detoxification

0.72	GO:0008017	microtubule binding
0.43	GO:0004096	catalase activity
0.39	GO:0020037	heme binding
0.32	GO:0005262	calcium channel activity
0.32	GO:0008083	growth factor activity
0.32	GO:0003677	DNA binding

0.82	GO:0001750	photoreceptor outer segment
0.67	GO:0001917	photoreceptor inner segment
0.67	GO:0097542	ciliary tip
0.65	GO:0032391	photoreceptor connecting cilium
0.64	GO:0005930	axoneme
0.61	GO:0005875	microtubule associated complex
0.41	GO:0005874	microtubule
0.32	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.43

EC:1.11.1.6

GO:0004096

sp|P56730|NETR_HUMAN
Neurotrypsin
Search

PRSS12

0.63	Neurotrypsin

0.67	GO:0006898	receptor-mediated endocytosis
0.60	GO:0006508	proteolysis
0.42	GO:0006887	exocytosis
0.40	GO:0051604	protein maturation

0.75	GO:0005044	scavenger receptor activity
0.68	GO:0004252	serine-type endopeptidase activity

0.45	GO:0043083	synaptic cleft
0.44	GO:0043195	terminal bouton
0.43	GO:0030425	dendrite
0.41	GO:0031410	cytoplasmic vesicle
0.37	GO:0005886	plasma membrane

0.68

GO:0004252

sp|P56746|CLD15_HUMAN
Claudin-15
Search

CLDN15

0.68

Claudin

0.41	GO:0035295	tube development
0.40	GO:0055123	digestive system development
0.40	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
0.39	GO:0048646	anatomical structure formation involved in morphogenesis
0.37	GO:0043269	regulation of ion transport
0.36	GO:0001889	liver development
0.36	GO:0006811	ion transport

0.62	GO:0005198	structural molecule activity
0.37	GO:0042802	identical protein binding

0.81	GO:0005923	bicellular tight junction
0.56	GO:0016328	lateral plasma membrane
0.33	GO:0005737	cytoplasm
0.33	GO:0012505	endomembrane system
0.32	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

sp|P56747|CLD6_HUMAN
Claudin-6
Search

0.70

Claudin

0.61	GO:0045216	cell-cell junction organization
0.52	GO:0070293	renal absorption
0.52	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
0.51	GO:0061436	establishment of skin barrier
0.50	GO:0051806	entry into cell of other organism involved in symbiotic interaction
0.50	GO:0044409	entry into host
0.48	GO:0019058	viral life cycle
0.48	GO:1902476	chloride transmembrane transport
0.46	GO:0003382	epithelial cell morphogenesis
0.45	GO:0051291	protein heterooligomerization

0.62	GO:0005198	structural molecule activity
0.62	GO:0104005	hijacked molecular function
0.48	GO:0005254	chloride channel activity
0.45	GO:0042802	identical protein binding
0.34	GO:0004888	transmembrane signaling receptor activity

0.81	GO:0005923	bicellular tight junction
0.65	GO:0016327	apicolateral plasma membrane
0.47	GO:0016328	lateral plasma membrane
0.44	GO:0005887	integral component of plasma membrane
0.40	GO:0043227	membrane-bounded organelle
0.39	GO:0009925	basal plasma membrane
0.38	GO:0043229	intracellular organelle
0.38	GO:0016324	apical plasma membrane
0.37	GO:0034707	chloride channel complex
0.34	GO:0043230	extracellular organelle

sp|P56748|CLD8_HUMAN
Claudin-8
Search

CLDN8

0.68

Claudin

0.45	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
0.41	GO:0003382	epithelial cell morphogenesis
0.41	GO:0070830	bicellular tight junction assembly
0.41	GO:0051291	protein heterooligomerization
0.40	GO:0001666	response to hypoxia
0.39	GO:0051260	protein homooligomerization
0.37	GO:0045471	response to ethanol
0.35	GO:0055113	epiboly involved in gastrulation with mouth forming second
0.35	GO:1902476	chloride transmembrane transport
0.32	GO:0007165	signal transduction

0.62	GO:0005198	structural molecule activity
0.41	GO:0042802	identical protein binding
0.35	GO:0005254	chloride channel activity
0.33	GO:0099600	transmembrane receptor activity
0.32	GO:0038023	signaling receptor activity

0.81	GO:0005923	bicellular tight junction
0.58	GO:0016327	apicolateral plasma membrane
0.53	GO:0016323	basolateral plasma membrane
0.41	GO:0016328	lateral plasma membrane
0.35	GO:0034707	chloride channel complex
0.35	GO:0005783	endoplasmic reticulum
0.35	GO:0070062	extracellular exosome
0.33	GO:0005887	integral component of plasma membrane

sp|P56749|CLD12_HUMAN
Claudin-12
Search

CLDN12

0.97	Claudin 12 (Predicted)

0.39

GO:0016338

calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules

0.58	GO:0005198	structural molecule activity
0.36	GO:0042802	identical protein binding

0.76	GO:0005923	bicellular tight junction
0.61	GO:0016328	lateral plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P56750|CLD17_HUMAN
Claudin-17
Search

0.69

Claudin

0.41	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
0.38	GO:1902476	chloride transmembrane transport

0.62	GO:0005198	structural molecule activity
0.38	GO:0005254	chloride channel activity
0.38	GO:0042802	identical protein binding

0.81	GO:0005923	bicellular tight junction
0.56	GO:0005886	plasma membrane
0.39	GO:0034707	chloride channel complex
0.35	GO:0005783	endoplasmic reticulum

sp|P56817|BACE1_HUMAN
Beta-secretase 1
Search

BACE1

0.97	Beta-site APP-cleaving enzyme 1

0.62	GO:0050435	amyloid-beta metabolic process
0.61	GO:0006508	proteolysis
0.56	GO:0050804	modulation of chemical synaptic transmission
0.45	GO:0030163	protein catabolic process
0.35	GO:0007613	memory
0.35	GO:0031643	positive regulation of myelination
0.35	GO:0022011	myelination in peripheral nervous system
0.34	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process
0.33	GO:0065008	regulation of biological quality
0.33	GO:0044267	cellular protein metabolic process

0.70	GO:0070001	aspartic-type peptidase activity
0.65	GO:0004175	endopeptidase activity
0.60	GO:0001540	amyloid-beta binding
0.51	GO:0019899	enzyme binding
0.35	GO:0008798	beta-aspartyl-peptidase activity

0.59	GO:0005771	multivesicular body
0.56	GO:0005769	early endosome
0.56	GO:0005802	trans-Golgi network
0.55	GO:0030424	axon
0.49	GO:0005887	integral component of plasma membrane
0.40	GO:0045121	membrane raft
0.39	GO:0030659	cytoplasmic vesicle membrane
0.39	GO:0009986	cell surface
0.38	GO:0005783	endoplasmic reticulum
0.37	GO:0070931	Golgi-associated vesicle lumen

0.35

EC:3.4.19.5

GO:0008798

sp|P56851|EP3B_HUMAN
Epididymal secretory protein E3-beta
Search

0.97	Epididymal secretory protein 3

0.52	GO:0007321	sperm displacement
0.47	GO:0090305	nucleic acid phosphodiester bond hydrolysis

0.48	GO:0004519	endonuclease activity
0.42	GO:0005515	protein binding
0.41	GO:0003676	nucleic acid binding

0.47	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

sp|P56856|CLD18_HUMAN
Claudin-18
Search

CLDN18

0.72

Claudin

0.61	GO:2001205	negative regulation of osteoclast development
0.61	GO:0071847	TNFSF11-mediated signaling pathway
0.60	GO:0045779	negative regulation of bone resorption
0.57	GO:1900181	negative regulation of protein localization to nucleus
0.56	GO:0048565	digestive tract development
0.39	GO:0045471	response to ethanol
0.39	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
0.33	GO:0060322	head development

0.62	GO:0005198	structural molecule activity
0.36	GO:0042802	identical protein binding
0.32	GO:0003677	DNA binding

0.81	GO:0005923	bicellular tight junction
0.55	GO:0005886	plasma membrane
0.32	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|P56880|CLD20_HUMAN
Claudin-20
Search

CLDN20

0.72

Claudin

0.38	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
0.34	GO:0032463	negative regulation of protein homooligomerization
0.34	GO:0045471	response to ethanol
0.34	GO:0007162	negative regulation of cell adhesion
0.33	GO:2000147	positive regulation of cell motility
0.33	GO:0008284	positive regulation of cell proliferation
0.33	GO:0043066	negative regulation of apoptotic process

0.62	GO:0005198	structural molecule activity
0.35	GO:0042802	identical protein binding
0.33	GO:0050839	cell adhesion molecule binding

0.81	GO:0005923	bicellular tight junction
0.55	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|P56915|GSC_HUMAN
Homeobox protein goosecoid
Search

GSC

0.96	Homeobox protein goosecoid

0.64	GO:0014036	neural crest cell fate specification
0.61	GO:0042474	middle ear morphogenesis
0.60	GO:0023019	signal transduction involved in regulation of gene expression
0.60	GO:0021904	dorsal/ventral neural tube patterning
0.58	GO:0048644	muscle organ morphogenesis
0.57	GO:0048704	embryonic skeletal system morphogenesis
0.57	GO:0030178	negative regulation of Wnt signaling pathway
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0030900	forebrain development

0.63	GO:0043565	sequence-specific DNA binding
0.59	GO:0001103	RNA polymerase II repressing transcription factor binding
0.57	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.54	GO:0001012	RNA polymerase II regulatory region DNA binding
0.51	GO:0003690	double-stranded DNA binding
0.32	GO:0004000	adenosine deaminase activity

0.61	GO:0005634	nucleus
0.53	GO:0005667	transcription factor complex
0.49	GO:0031974	membrane-enclosed lumen
0.44	GO:0044446	intracellular organelle part

0.32

EC:3.5.4.4

GO:0004000

sp|P56937|DHB7_HUMAN
3-keto-steroid reductase
Search

HSD17B7

0.86	17-beta hydroxysteroid dehydrogenase

0.60	GO:0006695	cholesterol biosynthetic process
0.42	GO:0055114	oxidation-reduction process
0.41	GO:0006703	estrogen biosynthetic process
0.39	GO:0016310	phosphorylation
0.37	GO:1990637	response to prolactin
0.36	GO:0060135	maternal process involved in female pregnancy
0.36	GO:0032355	response to estradiol
0.36	GO:0021766	hippocampus development
0.36	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.35	GO:0018212	peptidyl-tyrosine modification

0.64	GO:0000253	3-keto sterol reductase activity
0.41	GO:0004303	estradiol 17-beta-dehydrogenase activity
0.39	GO:0016301	kinase activity
0.37	GO:0005148	prolactin receptor binding
0.36	GO:0038064	collagen receptor activity
0.33	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.33	GO:0140096	catalytic activity, acting on a protein
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.52	GO:0005783	endoplasmic reticulum
0.36	GO:0005886	plasma membrane
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

0.64

EC:1.1.1.270

GO:0000253

sp|P56945|BCAR1_HUMAN
Breast cancer anti-estrogen resistance protein 1
Search

BCAR1

0.88	Breast cancer anti-estrogen resistance protein 1

0.60	GO:0007165	signal transduction
0.43	GO:0032869	cellular response to insulin stimulus
0.42	GO:0030335	positive regulation of cell migration
0.42	GO:0002253	activation of immune response
0.42	GO:0071363	cellular response to growth factor stimulus
0.42	GO:0016477	cell migration
0.41	GO:0035728	response to hepatocyte growth factor
0.41	GO:0007015	actin filament organization
0.40	GO:0010594	regulation of endothelial cell migration
0.38	GO:0051240	positive regulation of multicellular organismal process

0.64	GO:0004871	signal transducer activity
0.39	GO:0019901	protein kinase binding
0.39	GO:0017124	SH3 domain binding

0.43	GO:0001726	ruffle
0.43	GO:0005925	focal adhesion
0.40	GO:0030027	lamellipodium
0.38	GO:0015629	actin cytoskeleton
0.37	GO:0005829	cytosol
0.35	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P56962|STX17_HUMAN
Syntaxin-17
Search

STX17

0.96	Syntaxin-17 isoform A

0.86	GO:0097111	endoplasmic reticulum-Golgi intermediate compartment organization
0.85	GO:0097352	autophagosome maturation
0.78	GO:0006888	ER to Golgi vesicle-mediated transport
0.62	GO:0061025	membrane fusion
0.62	GO:0006886	intracellular protein transport
0.60	GO:0034497	protein localization to phagophore assembly site
0.58	GO:0007030	Golgi organization
0.57	GO:0140056	organelle localization by membrane tethering
0.48	GO:0048284	organelle fusion
0.48	GO:0016050	vesicle organization

0.82	GO:0000149	SNARE binding
0.72	GO:0005484	SNAP receptor activity
0.58	GO:0019903	protein phosphatase binding
0.38	GO:0019901	protein kinase binding

0.61	GO:0000421	autophagosome membrane
0.60	GO:0030897	HOPS complex
0.60	GO:0031201	SNARE complex
0.58	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.58	GO:0044233	ER-mitochondrion membrane contact site
0.52	GO:0005789	endoplasmic reticulum membrane
0.46	GO:0005739	mitochondrion
0.42	GO:0097425	smooth endoplasmic reticulum part
0.40	GO:0012507	ER to Golgi transport vesicle membrane
0.39	GO:0005886	plasma membrane

sp|P56975|NRG3_HUMAN
Pro-neuregulin-3, membrane-bound isoform
Search

NRG3

0.85	Pro-neuregulin-3, membrane-bound isoform

0.53	GO:0021842	chemorepulsion involved in interneuron migration from the subpallium to the cortex
0.52	GO:2001223	negative regulation of neuron migration
0.50	GO:0060596	mammary placode formation
0.47	GO:0007389	pattern specification process
0.44	GO:0035556	intracellular signal transduction
0.39	GO:0010469	regulation of receptor activity
0.39	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity
0.37	GO:0001558	regulation of cell growth

0.52	GO:0045499	chemorepellent activity
0.40	GO:0008083	growth factor activity
0.39	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity
0.38	GO:0030971	receptor tyrosine kinase binding

0.44	GO:0005615	extracellular space
0.37	GO:0005622	intracellular
0.36	GO:0005887	integral component of plasma membrane

sp|P57052|RBM11_HUMAN
Splicing regulator RBM11
Search

RBM11

0.74	RNA binding motif protein 7

0.47	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.45	GO:0021693	cerebellar Purkinje cell layer structural organization
0.42	GO:0007409	axonogenesis
0.39	GO:0034599	cellular response to oxidative stress
0.36	GO:0000077	DNA damage checkpoint
0.30	GO:0090304	nucleic acid metabolic process
0.30	GO:0010467	gene expression

0.59	GO:0003723	RNA binding
0.39	GO:0042803	protein homodimerization activity
0.33	GO:0005524	ATP binding

0.41	GO:0005634	nucleus
0.38	GO:0031974	membrane-enclosed lumen
0.36	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|P57053|H2BFS_HUMAN
Histone H2B type F-S
Search

0.93	Histone H2B type F-S

0.51	GO:0006334	nucleosome assembly
0.42	GO:0002227	innate immune response in mucosa
0.41	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.41	GO:0019731	antibacterial humoral response
0.41	GO:0050830	defense response to Gram-positive bacterium
0.39	GO:0050829	defense response to Gram-negative bacterium
0.38	GO:0031640	killing of cells of other organism
0.36	GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway
0.35	GO:0021762	substantia nigra development
0.34	GO:0006352	DNA-templated transcription, initiation

0.74	GO:0046982	protein heterodimerization activity
0.55	GO:0003677	DNA binding
0.37	GO:0097677	STAT family protein binding
0.36	GO:0001530	lipopolysaccharide binding
0.35	GO:0044389	ubiquitin-like protein ligase binding
0.34	GO:0042802	identical protein binding
0.33	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.74	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.44	GO:0005829	cytosol
0.44	GO:0031974	membrane-enclosed lumen
0.39	GO:0005615	extracellular space
0.35	GO:1903561	extracellular vesicle
0.33	GO:0043234	protein complex
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0004553

sp|P57054|PIGP_HUMAN
Phosphatidylinositol N-acetylglucosaminyltransferase subunit P
Search

PIGP

0.96	Phosphatidylinositol N-acetylglucosaminyltransferase subunit P

0.76	GO:0006506	GPI anchor biosynthetic process
0.45	GO:1904103	regulation of convergent extension involved in gastrulation
0.43	GO:0060028	convergent extension involved in axis elongation
0.42	GO:0046328	regulation of JNK cascade
0.33	GO:0032259	methylation
0.33	GO:0045454	cell redox homeostasis
0.33	GO:0051603	proteolysis involved in cellular protein catabolic process
0.32	GO:0005975	carbohydrate metabolic process
0.32	GO:1903506	regulation of nucleic acid-templated transcription
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.82	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity
0.34	GO:0070569	uridylyltransferase activity
0.34	GO:0004077	biotin-[acetyl-CoA-carboxylase] ligase activity
0.33	GO:0008168	methyltransferase activity
0.33	GO:0004565	beta-galactosidase activity
0.33	GO:0070003	threonine-type peptidase activity
0.33	GO:0015002	heme-copper terminal oxidase activity
0.32	GO:0003700	DNA binding transcription factor activity
0.32	GO:0004175	endopeptidase activity

0.51	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex
0.33	GO:0005839	proteasome core complex
0.30	GO:0031224	intrinsic component of membrane

0.82

EC:2.4.1.198

GO:0017176

sp|P57055|DSCR6_HUMAN
Protein ripply3
Search

RIPPLY3

0.97	Ripply transcriptional repressor 3

0.82	GO:0060037	pharyngeal system development
0.78	GO:0000122	negative regulation of transcription by RNA polymerase II
0.74	GO:0007507	heart development
0.73	GO:0008285	negative regulation of cell proliferation
0.64	GO:0009880	embryonic pattern specification

0.50

GO:0005634

nucleus

sp|P57057|G6PT2_HUMAN
Glucose-6-phosphate exchanger SLC37A1
Search

SLC37A1

0.61	LOW QUALITY PROTEIN: glycerol-3-phosphate transporter

0.65	GO:0015712	hexose phosphate transport
0.56	GO:0035435	phosphate ion transmembrane transport
0.36	GO:0008643	carbohydrate transport
0.34	GO:0006127	glycerophosphate shuttle
0.33	GO:0015794	glycerol-3-phosphate transport
0.32	GO:0007165	signal transduction

0.66	GO:0061513	glucose 6-phosphate:inorganic phosphate antiporter activity
0.34	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.33	GO:0015169	glycerol-3-phosphate transmembrane transporter activity
0.32	GO:0046872	metal ion binding

0.57	GO:0030176	integral component of endoplasmic reticulum membrane
0.36	GO:0070062	extracellular exosome

0.34

EC:3.1.4.17

GO:0004114

sp|P57058|HUNK_HUMAN
Hormonally up-regulated neu tumor-associated kinase
Search

HUNK

0.96	Hormonally up-regulated neu tumor-associated kinase

0.63	GO:0006468	protein phosphorylation
0.43	GO:0035556	intracellular signal transduction
0.35	GO:0007275	multicellular organism development

0.63	GO:0004672	protein kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding

0.42	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|P57059|SIK1_HUMAN
Serine/threonine-protein kinase SIK1
Search

SIK1

0.83	Serine/threonine-protein kinase SIK1

0.64	GO:0010868	negative regulation of triglyceride biosynthetic process
0.63	GO:0006468	protein phosphorylation
0.62	GO:0032792	negative regulation of CREB transcription factor activity
0.60	GO:0043153	entrainment of circadian clock by photoperiod
0.59	GO:0010830	regulation of myotube differentiation
0.59	GO:0045721	negative regulation of gluconeogenesis
0.59	GO:0055007	cardiac muscle cell differentiation
0.58	GO:0043276	anoikis
0.54	GO:0007346	regulation of mitotic cell cycle
0.52	GO:0002028	regulation of sodium ion transport

0.67	GO:0004674	protein serine/threonine kinase activity
0.60	GO:0008140	cAMP response element binding protein binding
0.55	GO:0042826	histone deacetylase binding
0.55	GO:0019901	protein kinase binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0071889	14-3-3 protein binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0000287	magnesium ion binding

0.46	GO:0005634	nucleus
0.42	GO:0005829	cytosol

0.67

GO:0004674

sp|P57060|RWD2B_HUMAN
RWD domain-containing protein 2B
Search

RWDD2B

0.96	RWD domain-containing protein 2B

0.38	GO:0009116	nucleoside metabolic process
0.38	GO:0009156	ribonucleoside monophosphate biosynthetic process
0.37	GO:0009165	nucleotide biosynthetic process

0.48	GO:0005515	protein binding
0.44	GO:0016874	ligase activity
0.40	GO:0004749	ribose phosphate diphosphokinase activity
0.38	GO:0000287	magnesium ion binding

0.30

GO:0044425

membrane part

0.44	EC:6	GO:0016874
0.40	KEGG:R01049	GO:0004749

sp|P57071|PRD15_HUMAN
PR domain zinc finger protein 15
Search

PRDM15

0.95	PR domain zinc finger protein 15

0.36	GO:0006468	protein phosphorylation
0.35	GO:0032259	methylation
0.34	GO:0006351	transcription, DNA-templated
0.34	GO:1903506	regulation of nucleic acid-templated transcription
0.34	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.34	GO:0010468	regulation of gene expression
0.32	GO:0060319	primitive erythrocyte differentiation

0.51	GO:0003676	nucleic acid binding
0.37	GO:0046872	metal ion binding
0.36	GO:0004672	protein kinase activity
0.35	GO:0008168	methyltransferase activity
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.50	GO:0016604	nuclear body
0.30	GO:0016020	membrane

0.35

GO:0008168

sp|P57073|SOX8_HUMAN
Transcription factor SOX-8
Search

SOX8

0.97	Sex determining region Y-box 8

0.70	GO:0006357	regulation of transcription by RNA polymerase II
0.63	GO:0072289	metanephric nephron tubule formation
0.63	GO:0060221	retinal rod cell differentiation
0.63	GO:0072034	renal vesicle induction
0.62	GO:0072197	ureter morphogenesis
0.61	GO:0060018	astrocyte fate commitment
0.61	GO:0060009	Sertoli cell development
0.61	GO:0046533	negative regulation of photoreceptor cell differentiation
0.60	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis
0.60	GO:0033690	positive regulation of osteoblast proliferation

0.73	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.59	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding
0.52	GO:0046982	protein heterodimerization activity
0.51	GO:0008134	transcription factor binding
0.37	GO:0035326	enhancer binding
0.37	GO:0003682	chromatin binding
0.37	GO:0034236	protein kinase A catalytic subunit binding
0.36	GO:0097157	pre-mRNA intronic binding
0.35	GO:0008013	beta-catenin binding
0.34	GO:0004672	protein kinase activity

0.61	GO:0005634	nucleus
0.52	GO:0005667	transcription factor complex
0.44	GO:0044446	intracellular organelle part
0.40	GO:0005737	cytoplasm
0.34	GO:0070013	intracellular organelle lumen
0.30	GO:0016020	membrane

sp|P57075|UBS3A_HUMAN
Ubiquitin-associated and SH3 domain-containing protein A
Search

UBASH3A

0.93	Ubiquitin-associated and SH3 domain-containing protein A

0.83	GO:0050860	negative regulation of T cell receptor signaling pathway
0.74	GO:0001817	regulation of cytokine production
0.57	GO:0070527	platelet aggregation
0.55	GO:0038065	collagen-activated signaling pathway
0.55	GO:0045779	negative regulation of bone resorption
0.55	GO:0090331	negative regulation of platelet aggregation
0.54	GO:0045671	negative regulation of osteoclast differentiation
0.53	GO:0051279	regulation of release of sequestered calcium ion into cytosol
0.52	GO:0043393	regulation of protein binding
0.51	GO:0006469	negative regulation of protein kinase activity

0.52	GO:0051219	phosphoprotein binding
0.48	GO:0004725	protein tyrosine phosphatase activity
0.48	GO:0042802	identical protein binding
0.35	GO:0031625	ubiquitin protein ligase binding

0.68	GO:0005794	Golgi apparatus
0.66	GO:0005654	nucleoplasm
0.44	GO:0070062	extracellular exosome
0.41	GO:0005829	cytosol

0.48

EC:3.1.3.48

GO:0004725

sp|P57076|CU059_HUMAN
UPF0769 protein C21orf59
Search

0.67	GO:0048858	cell projection morphogenesis
0.63	GO:0003352	regulation of cilium movement
0.58	GO:0060271	cilium assembly
0.56	GO:0048488	synaptic vesicle endocytosis
0.53	GO:0046856	phosphatidylinositol dephosphorylation
0.42	GO:0090660	cerebrospinal fluid circulation
0.41	GO:0072114	pronephros morphogenesis
0.39	GO:0007368	determination of left/right symmetry

0.56	GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity
0.44	GO:0003723	RNA binding

0.51	GO:0045202	synapse
0.50	GO:0005929	cilium
0.47	GO:0005856	cytoskeleton
0.43	GO:0005829	cytosol
0.39	GO:0005634	nucleus

sp|P57077|M3KCL_HUMAN
MAP3K7 C-terminal-like protein
Search

MAP3K7CL

0.95	MAP3K7 C-terminal like

0.82	GO:0000186	activation of MAPKK activity
0.77	GO:0000165	MAPK cascade

0.83	GO:0004709	MAP kinase kinase kinase activity
0.45	GO:0005515	protein binding

0.54	GO:0005829	cytosol
0.49	GO:0005634	nucleus

0.83

EC:2.7.11 EC:2.7.11.25

GO:0004709

sp|P57078|RIPK4_HUMAN
Receptor-interacting serine/threonine-protein kinase 4
Search

RIPK4

0.93	Receptor-interacting serine-threonine kinase 4

0.59	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.57	GO:0016310	phosphorylation
0.56	GO:0002009	morphogenesis of an epithelium
0.54	GO:0006464	cellular protein modification process

0.59	GO:0016301	kinase activity
0.55	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.52	GO:0140096	catalytic activity, acting on a protein
0.50	GO:0030554	adenyl nucleotide binding
0.49	GO:0032553	ribonucleotide binding
0.49	GO:0008144	drug binding
0.49	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0005515	protein binding
0.33	GO:0003676	nucleic acid binding

0.39	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.55

GO:0016773

sp|P57081|WDR4_HUMAN
tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4
Search

WDR4

0.97	tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4

0.74	GO:0036265	RNA (guanine-N7)-methylation
0.66	GO:0030488	tRNA methylation
0.33	GO:0008618	7-methylguanosine metabolic process

0.58	GO:0008168	methyltransferase activity
0.50	GO:0140101	catalytic activity, acting on a tRNA
0.34	GO:0005515	protein binding

0.58	GO:0043527	tRNA methyltransferase complex
0.56	GO:0005634	nucleus
0.51	GO:0005829	cytosol
0.36	GO:0031974	membrane-enclosed lumen
0.34	GO:0044446	intracellular organelle part
0.33	GO:0045271	respiratory chain complex I
0.33	GO:1990204	oxidoreductase complex
0.32	GO:0031090	organelle membrane
0.32	GO:0005739	mitochondrion
0.32	GO:0031975	envelope

0.58

GO:0008168

sp|P57082|TBX4_HUMAN
T-box transcription factor TBX4
Search

TBX4

0.97	T-box transcription factor TBX4

0.63	GO:0035108	limb morphogenesis
0.63	GO:0035113	embryonic appendage morphogenesis
0.59	GO:0030324	lung development
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0048705	skeletal system morphogenesis
0.56	GO:0010468	regulation of gene expression
0.56	GO:0002009	morphogenesis of an epithelium
0.56	GO:0072359	circulatory system development
0.56	GO:0006351	transcription, DNA-templated

0.61	GO:0003700	DNA binding transcription factor activity
0.53	GO:0003677	DNA binding
0.41	GO:0001067	regulatory region nucleic acid binding
0.40	GO:0008134	transcription factor binding
0.35	GO:0030274	LIM domain binding

0.61	GO:0005634	nucleus
0.40	GO:0032993	protein-DNA complex
0.35	GO:0097517	contractile actin filament bundle
0.35	GO:0042641	actomyosin
0.35	GO:0005884	actin filament
0.35	GO:0005737	cytoplasm
0.33	GO:0043233	organelle lumen

sp|P57086|SCND1_HUMAN
SCAN domain-containing protein 1
Search

SCAND1

0.97	Leucine-rich-domain inter-acting protein 1

0.57	GO:0006355	regulation of transcription, DNA-templated
0.43	GO:0006351	transcription, DNA-templated
0.37	GO:0030851	granulocyte differentiation
0.36	GO:0006915	apoptotic process
0.36	GO:0042127	regulation of cell proliferation
0.32	GO:0006508	proteolysis
0.32	GO:0000160	phosphorelay signal transduction system

0.61	GO:0003700	DNA binding transcription factor activity
0.52	GO:0003713	transcription coactivator activity
0.42	GO:0046872	metal ion binding
0.42	GO:0003676	nucleic acid binding
0.38	GO:0042802	identical protein binding
0.33	GO:0004252	serine-type endopeptidase activity

0.60	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.33

GO:0004252

sp|P57087|JAM2_HUMAN
Junctional adhesion molecule B
Search

JAM2

0.97	Junctional adhesion molecule B

0.60	GO:0007162	negative regulation of cell adhesion
0.37	GO:0050900	leukocyte migration
0.37	GO:0030198	extracellular matrix organization
0.36	GO:0007520	myoblast fusion
0.36	GO:0007155	cell adhesion
0.35	GO:0048534	hematopoietic or lymphoid organ development
0.34	GO:0090557	establishment of endothelial intestinal barrier
0.34	GO:0050892	intestinal absorption
0.34	GO:0045777	positive regulation of blood pressure
0.34	GO:0034260	negative regulation of GTPase activity

0.55	GO:0046982	protein heterodimerization activity
0.34	GO:0104005	hijacked molecular function
0.34	GO:0030165	PDZ domain binding
0.34	GO:0045296	cadherin binding

0.39	GO:0005923	bicellular tight junction
0.35	GO:0005887	integral component of plasma membrane
0.34	GO:0036057	slit diaphragm
0.33	GO:0070062	extracellular exosome
0.33	GO:0031410	cytoplasmic vesicle

sp|P57088|TMM33_HUMAN
Transmembrane protein 33
Search

TMEM33

0.97	LOW QUALITY PROTEIN: transmembrane protein 33

0.60	GO:1903896	positive regulation of IRE1-mediated unfolded protein response
0.59	GO:1903899	positive regulation of PERK-mediated unfolded protein response
0.59	GO:1903371	regulation of endoplasmic reticulum tubular network organization
0.53	GO:0034976	response to endoplasmic reticulum stress
0.50	GO:0051292	nuclear pore complex assembly
0.50	GO:0071786	endoplasmic reticulum tubular network organization
0.43	GO:0034613	cellular protein localization
0.33	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:0098655	cation transmembrane transport

0.47	GO:0017056	structural constituent of nuclear pore
0.34	GO:0005515	protein binding
0.33	GO:0004930	G-protein coupled receptor activity
0.33	GO:0008324	cation transmembrane transporter activity

0.56	GO:0042470	melanosome
0.53	GO:0005635	nuclear envelope
0.52	GO:0030176	integral component of endoplasmic reticulum membrane
0.40	GO:0043234	protein complex
0.36	GO:0070062	extracellular exosome

sp|P57103|NAC3_HUMAN
Sodium/calcium exchanger 3
Search

SLC8A3

0.91	Solute carrier family 8 (sodium/calcium exchanger), member 3

0.75	GO:0035725	sodium ion transmembrane transport
0.74	GO:0006816	calcium ion transport
0.67	GO:0014819	regulation of skeletal muscle contraction
0.65	GO:0051560	mitochondrial calcium ion homeostasis
0.65	GO:0060291	long-term synaptic potentiation
0.64	GO:0048709	oligodendrocyte differentiation
0.63	GO:0071456	cellular response to hypoxia
0.63	GO:0002244	hematopoietic progenitor cell differentiation
0.63	GO:0007613	memory
0.63	GO:0042552	myelination

0.83	GO:0005432	calcium:sodium antiporter activity
0.70	GO:0099580	ion antiporter activity involved in regulation of postsynaptic membrane potential

0.63	GO:0031594	neuromuscular junction
0.63	GO:0042383	sarcolemma
0.60	GO:0048471	perinuclear region of cytoplasm
0.59	GO:0005741	mitochondrial outer membrane
0.55	GO:0005789	endoplasmic reticulum membrane
0.53	GO:0031226	intrinsic component of plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P57105|SYJ2B_HUMAN
Synaptojanin-2-binding protein
Search

SYNJ2BP

0.97	Putative pdz domain containing protein found in a variety of eumetazoan signaling molecules

0.55	GO:1903671	negative regulation of sprouting angiogenesis
0.54	GO:0001937	negative regulation of endothelial cell proliferation
0.54	GO:0010596	negative regulation of endothelial cell migration
0.54	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.53	GO:0008593	regulation of Notch signaling pathway
0.49	GO:0007266	Rho protein signal transduction
0.48	GO:0030100	regulation of endocytosis
0.44	GO:0006605	protein targeting
0.41	GO:0048312	intracellular distribution of mitochondria
0.38	GO:0032927	positive regulation of activin receptor signaling pathway

0.40	GO:0008022	protein C-terminus binding
0.39	GO:0070699	type II activin receptor binding

0.46	GO:0005739	mitochondrion
0.41	GO:0031967	organelle envelope
0.41	GO:0031090	organelle membrane
0.39	GO:0098805	whole membrane
0.38	GO:0019867	outer membrane
0.37	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0009986	cell surface
0.34	GO:0005911	cell-cell junction
0.30	GO:0016021	integral component of membrane

sp|P57678|GEMI4_HUMAN
Gem-associated protein 4
Search

GEMIN4

0.97	Gem nuclear organelle associated protein 4

0.81	GO:0000387	spliceosomal snRNP assembly
0.69	GO:0006364	rRNA processing
0.35	GO:0051170	nuclear import

0.38	GO:0043021	ribonucleoprotein complex binding
0.34	GO:0005515	protein binding

0.85	GO:0032797	SMN complex
0.62	GO:0034719	SMN-Sm protein complex
0.57	GO:0016604	nuclear body
0.52	GO:0005829	cytosol
0.48	GO:0030532	small nuclear ribonucleoprotein complex
0.39	GO:0005730	nucleolus
0.38	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

sp|P57679|EVC_HUMAN
Ellis-van Creveld syndrome protein
Search

EVC

0.97	Ellis van Creveld syndrome

0.84	GO:0007224	smoothened signaling pathway
0.63	GO:0003416	endochondral bone growth
0.63	GO:0045880	positive regulation of smoothened signaling pathway
0.41	GO:0051216	cartilage development
0.37	GO:0007517	muscle organ development

0.34

GO:0005515

protein binding

0.62	GO:0060170	ciliary membrane
0.60	GO:0036064	ciliary basal body
0.50	GO:0098797	plasma membrane protein complex
0.34	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|P57682|KLF3_HUMAN
Krueppel-like factor 3
Search

KLF3

0.97	Kruppel like factor 3

0.57	GO:0000122	negative regulation of transcription by RNA polymerase II
0.41	GO:1901653	cellular response to peptide
0.34	GO:0006351	transcription, DNA-templated
0.34	GO:0045944	positive regulation of transcription by RNA polymerase II
0.34	GO:0007275	multicellular organism development

0.55	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.38	GO:0003700	DNA binding transcription factor activity
0.34	GO:0005515	protein binding
0.34	GO:0046872	metal ion binding
0.33	GO:0000987	proximal promoter sequence-specific DNA binding
0.33	GO:0003714	transcription corepressor activity

0.52	GO:0005654	nucleoplasm
0.39	GO:0005829	cytosol
0.33	GO:0016235	aggresome
0.30	GO:0031224	intrinsic component of membrane

sp|P57721|PCBP3_HUMAN
Poly(rC)-binding protein 3
Search

PCBP3

0.89	LOW QUALITY PROTEIN: poly(RC)-binding protein 3

0.48	GO:0000122	negative regulation of transcription by RNA polymerase II
0.34	GO:0016071	mRNA metabolic process

0.59	GO:0003723	RNA binding
0.55	GO:1990829	C-rich single-stranded DNA binding
0.50	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.46	GO:0003690	double-stranded DNA binding

0.36	GO:0070062	extracellular exosome
0.35	GO:0005829	cytosol
0.34	GO:0030529	intracellular ribonucleoprotein complex
0.34	GO:0005634	nucleus

sp|P57723|PCBP4_HUMAN
Poly(rC)-binding protein 4
Search

PCBP4

0.96	Poly(rC)-binding protein 4

0.58	GO:0043488	regulation of mRNA stability
0.40	GO:1902163	negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
0.38	GO:0048025	negative regulation of mRNA splicing, via spliceosome
0.36	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

0.59	GO:0003723	RNA binding
0.34	GO:0003677	DNA binding

0.50	GO:0005829	cytosol
0.35	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016020	membrane

sp|P57727|TMPS3_HUMAN
Transmembrane protease serine 3
Search

TMPRSS3

0.96	Transmembrane protease serine 3

0.68	GO:0006898	receptor-mediated endocytosis
0.63	GO:0006883	cellular sodium ion homeostasis
0.61	GO:0006508	proteolysis
0.58	GO:0007605	sensory perception of sound
0.49	GO:0065009	regulation of molecular function
0.34	GO:0007596	blood coagulation
0.33	GO:0070684	seminal clot liquefaction
0.33	GO:0019221	cytokine-mediated signaling pathway
0.33	GO:0043010	camera-type eye development
0.33	GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway

0.77	GO:0005044	scavenger receptor activity
0.69	GO:0004252	serine-type endopeptidase activity
0.61	GO:0017080	sodium channel regulator activity
0.33	GO:0004896	cytokine receptor activity
0.33	GO:0005509	calcium ion binding
0.33	GO:0004792	thiosulfate sulfurtransferase activity

0.57	GO:0043025	neuronal cell body
0.53	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0005576	extracellular region
0.33	GO:0031982	vesicle
0.32	GO:0005887	integral component of plasma membrane
0.32	GO:0097223	sperm part

0.69	EC:3.4.21	GO:0004252
0.33	KEGG:R01931	GO:0004792

sp|P57729|RAB38_HUMAN
Ras-related protein Rab-38
Search

RAB38

0.94	Ras-related protein Rab-38

0.68	GO:0016192	vesicle-mediated transport
0.46	GO:0032438	melanosome organization
0.44	GO:0090383	phagosome acidification
0.44	GO:0035646	endosome to melanosome transport
0.40	GO:0007005	mitochondrion organization
0.40	GO:0070925	organelle assembly
0.40	GO:0072657	protein localization to membrane
0.40	GO:0060155	platelet dense granule organization
0.36	GO:0043687	post-translational protein modification
0.36	GO:0015031	protein transport

0.67	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0036461	BLOC-2 complex binding
0.45	GO:0035651	AP-3 adaptor complex binding
0.44	GO:0035650	AP-1 adaptor complex binding
0.44	GO:0030742	GTP-dependent protein binding
0.37	GO:0035612	AP-2 adaptor complex binding

0.78	GO:0005802	trans-Golgi network
0.71	GO:0031982	vesicle
0.42	GO:0044233	ER-mitochondrion membrane contact site
0.41	GO:0005764	lysosome
0.40	GO:0098805	whole membrane
0.40	GO:0098588	bounding membrane of organelle
0.38	GO:0005739	mitochondrion
0.36	GO:0005783	endoplasmic reticulum
0.36	GO:0005829	cytosol
0.34	GO:0031974	membrane-enclosed lumen

sp|P57730|CAR18_HUMAN
Caspase recruitment domain-containing protein 18
Search

CARD18

0.97	Caspase recruitment domain-containing protein 18

0.74	GO:0042981	regulation of apoptotic process
0.66	GO:0050713	negative regulation of interleukin-1 beta secretion
0.65	GO:0097340	inhibition of cysteine-type endopeptidase activity
0.61	GO:0032091	negative regulation of protein binding
0.52	GO:0097194	execution phase of apoptosis
0.50	GO:0006508	proteolysis
0.49	GO:0050727	regulation of inflammatory response
0.43	GO:0006952	defense response
0.43	GO:0051882	mitochondrial depolarization
0.42	GO:0050717	positive regulation of interleukin-1 alpha secretion

0.67	GO:0050700	CARD domain binding
0.65	GO:0089720	caspase binding
0.62	GO:0004197	cysteine-type endopeptidase activity
0.43	GO:0004869	cysteine-type endopeptidase inhibitor activity
0.39	GO:0019900	kinase binding
0.39	GO:0042802	identical protein binding

0.53	GO:0072557	IPAF inflammasome complex
0.53	GO:0097169	AIM2 inflammasome complex
0.53	GO:0072559	NLRP3 inflammasome complex
0.47	GO:0072558	NLRP1 inflammasome complex
0.42	GO:0097179	protease inhibitor complex
0.37	GO:0005576	extracellular region
0.36	GO:0005739	mitochondrion

0.62

EC:3.4.22

GO:0004197

sp|P57735|RAB25_HUMAN
Ras-related protein Rab-25
Search

RAB25

0.92	Putative rab subfamily protein of small gtpase

0.59	GO:0031268	pseudopodium organization
0.56	GO:0003382	epithelial cell morphogenesis
0.55	GO:0010634	positive regulation of epithelial cell migration
0.53	GO:0060627	regulation of vesicle-mediated transport
0.52	GO:0008284	positive regulation of cell proliferation
0.38	GO:0008104	protein localization
0.37	GO:0042886	amide transport
0.36	GO:0071702	organic substance transport
0.36	GO:0006887	exocytosis
0.36	GO:0045056	transcytosis

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.57	GO:0031489	myosin V binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0045296	cadherin binding

0.57	GO:0031143	pseudopodium
0.50	GO:0031410	cytoplasmic vesicle
0.40	GO:0031253	cell projection membrane
0.36	GO:0070062	extracellular exosome
0.35	GO:0012505	endomembrane system
0.34	GO:0090619	meiotic spindle pole
0.34	GO:0098805	whole membrane
0.34	GO:0090726	cortical dynamic polarity patch
0.34	GO:0098588	bounding membrane of organelle
0.34	GO:0005628	prospore membrane

sp|P57737|CORO7_HUMAN
Coronin-7
Search

CORO7

0.70

Coronin

0.53	GO:0007030	Golgi organization
0.53	GO:0030010	establishment of cell polarity
0.51	GO:0007015	actin filament organization
0.51	GO:0016477	cell migration
0.42	GO:0006895	Golgi to endosome transport
0.40	GO:0051258	protein polymerization
0.38	GO:0015031	protein transport

0.40

GO:0003779

actin binding

0.72	GO:0005794	Golgi apparatus
0.39	GO:0031410	cytoplasmic vesicle
0.39	GO:0098588	bounding membrane of organelle
0.38	GO:0005829	cytosol
0.38	GO:0031984	organelle subcompartment
0.30	GO:0016021	integral component of membrane

sp|P57738|TCTA_HUMAN
T-cell leukemia translocation-altered gene protein
Search

TCTA

0.97	T-cell leukemia translocation altered gene

0.71	GO:0072675	osteoclast fusion
0.69	GO:0045671	negative regulation of osteoclast differentiation

0.40	GO:0005622	intracellular
0.30	GO:0044425	membrane part

sp|P57739|CLD2_HUMAN
Claudin-2
Search

CLDN2

0.68

Claudin

0.64	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
0.33	GO:0006461	protein complex assembly

0.62	GO:0005198	structural molecule activity
0.54	GO:0042802	identical protein binding

0.81	GO:0005923	bicellular tight junction
0.55	GO:0005886	plasma membrane
0.39	GO:0070062	extracellular exosome
0.34	GO:0005783	endoplasmic reticulum
0.30	GO:0044425	membrane part

sp|P57740|NU107_HUMAN
Nuclear pore complex protein Nup107
Search

NUP107

0.91	Nucleoporin 107

0.77	GO:0051292	nuclear pore complex assembly
0.72	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.70	GO:0008585	female gonad development
0.68	GO:0051028	mRNA transport
0.68	GO:0006405	RNA export from nucleus
0.57	GO:0000973	posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery
0.53	GO:0006606	protein import into nucleus
0.50	GO:0010467	gene expression
0.42	GO:2001141	regulation of RNA biosynthetic process
0.42	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.80

GO:0017056

structural constituent of nuclear pore

0.78	GO:0005643	nuclear pore
0.67	GO:0034399	nuclear periphery
0.66	GO:0031965	nuclear membrane
0.65	GO:0000776	kinetochore
0.30	GO:0016021	integral component of membrane

sp|P57764|GSDMD_HUMAN
Gasdermin-D
Search

GSDMD

0.96	Gasdermin domain-containing protein 1

0.83	GO:0070269	pyroptosis
0.80	GO:0050718	positive regulation of interleukin-1 beta secretion
0.79	GO:0046931	pore complex assembly
0.76	GO:0050830	defense response to Gram-positive bacterium
0.75	GO:0050829	defense response to Gram-negative bacterium
0.70	GO:0051260	protein homooligomerization
0.70	GO:0019835	cytolysis
0.68	GO:0035915	pore formation in membrane of other organism
0.65	GO:0031668	cellular response to extracellular stimulus
0.48	GO:0006954	inflammatory response

0.82	GO:1901612	cardiolipin binding
0.80	GO:0070300	phosphatidic acid binding
0.79	GO:0001786	phosphatidylserine binding
0.77	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.75	GO:0070273	phosphatidylinositol-4-phosphate binding
0.39	GO:0005515	protein binding

0.82	GO:0072559	NLRP3 inflammasome complex
0.70	GO:0005654	nucleoplasm
0.66	GO:0005615	extracellular space
0.52	GO:0005886	plasma membrane
0.48	GO:1904724	tertiary granule lumen
0.48	GO:0035580	specific granule lumen
0.48	GO:1904813	ficolin-1-rich granule lumen

sp|P57768|SNX16_HUMAN
Sorting nexin-16
Search

SNX16

0.96	Sorting nexin-16 isoform a

0.61	GO:0006622	protein targeting to lysosome
0.61	GO:0045022	early endosome to late endosome transport
0.60	GO:0008333	endosome to lysosome transport

0.76	GO:0035091	phosphatidylinositol binding
0.51	GO:0042802	identical protein binding

0.62	GO:0031313	extrinsic component of endosome membrane
0.57	GO:0005770	late endosome
0.57	GO:0005769	early endosome
0.50	GO:0005829	cytosol
0.43	GO:0043231	intracellular membrane-bounded organelle

sp|P57771|RGS8_HUMAN
Regulator of G-protein signaling 8
Search

RGS8

0.97	Regulator of G-protein signaling 8

0.70	GO:0043547	positive regulation of GTPase activity
0.65	GO:0007186	G-protein coupled receptor signaling pathway
0.40	GO:0060159	regulation of dopamine receptor signaling pathway
0.39	GO:0009968	negative regulation of signal transduction
0.39	GO:0095500	acetylcholine receptor signaling pathway
0.34	GO:0008591	regulation of Wnt signaling pathway, calcium modulating pathway
0.34	GO:0061053	somite development
0.33	GO:0007601	visual perception

0.70	GO:0005096	GTPase activator activity
0.35	GO:0001965	G-protein alpha-subunit binding
0.33	GO:0005516	calmodulin binding

0.40	GO:0032809	neuronal cell body membrane
0.39	GO:0043204	perikaryon
0.38	GO:0030425	dendrite
0.38	GO:0005737	cytoplasm
0.38	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.35	GO:0005634	nucleus
0.33	GO:0045121	membrane raft
0.30	GO:0031224	intrinsic component of membrane

sp|P57772|SELB_HUMAN
Selenocysteine-specific elongation factor
Search

EEFSEC

0.73	Selenocysteine-specific elongation factor

0.65	GO:0006414	translational elongation
0.50	GO:0006417	regulation of translation
0.33	GO:0015031	protein transport

0.66	GO:0003746	translation elongation factor activity
0.65	GO:0003924	GTPase activity
0.64	GO:0032550	purine ribonucleoside binding
0.64	GO:0019001	guanyl nucleotide binding
0.61	GO:0035368	selenocysteine insertion sequence binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0043021	ribonucleoprotein complex binding
0.49	GO:0000049	tRNA binding
0.33	GO:0005515	protein binding

0.45	GO:0030529	intracellular ribonucleoprotein complex
0.45	GO:0005739	mitochondrion
0.35	GO:0005634	nucleus
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|P57773|CXA9_HUMAN
Gap junction alpha-9 protein
Search

GJA9

0.58	Gap junction protein (Fragment)

0.60	GO:0007154	cell communication
0.47	GO:0050908	detection of light stimulus involved in visual perception
0.46	GO:0007416	synapse assembly
0.44	GO:0007276	gamete generation
0.39	GO:0055085	transmembrane transport

0.50	GO:0005243	gap junction channel activity
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0019001	guanyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.32	GO:0003677	DNA binding

0.83	GO:0005922	connexin complex
0.30	GO:0016021	integral component of membrane

sp|P57775|FBXW4_HUMAN
F-box/WD repeat-containing protein 4
Search

FBXW4

0.97	F-box and WD repeat domain containing 4

0.85	GO:0002053	positive regulation of mesenchymal cell proliferation
0.83	GO:0042733	embryonic digit morphogenesis
0.80	GO:0051216	cartilage development
0.65	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
0.44	GO:0016567	protein ubiquitination
0.42	GO:0016055	Wnt signaling pathway
0.40	GO:0043687	post-translational protein modification

0.44	GO:0004842	ubiquitin-protein transferase activity
0.36	GO:0005515	protein binding

0.64	GO:0019005	SCF ubiquitin ligase complex
0.37	GO:0005829	cytosol

0.44

KEGG:R03876

GO:0004842

sp|P57789|KCNKA_HUMAN
Potassium channel subfamily K member 10
Search

KCNK10

0.97	Potassium channel TREK-2

0.72	GO:0071805	potassium ion transmembrane transport
0.52	GO:0030322	stabilization of membrane potential
0.40	GO:0007613	memory
0.38	GO:0007186	G-protein coupled receptor signaling pathway
0.36	GO:0034765	regulation of ion transmembrane transport
0.36	GO:1900039	positive regulation of cellular response to hypoxia
0.36	GO:0060044	negative regulation of cardiac muscle cell proliferation
0.35	GO:0090102	cochlea development
0.35	GO:0048678	response to axon injury
0.35	GO:2000279	negative regulation of DNA biosynthetic process

0.75	GO:0005267	potassium channel activity
0.53	GO:0022842	narrow pore channel activity
0.41	GO:0022832	voltage-gated channel activity
0.41	GO:0022839	ion gated channel activity
0.41	GO:0008381	mechanosensitive ion channel activity
0.34	GO:0019870	potassium channel inhibitor activity
0.33	GO:0005515	protein binding

0.44	GO:0005887	integral component of plasma membrane
0.39	GO:0034705	potassium channel complex
0.36	GO:0044305	calyx of Held
0.36	GO:0097449	astrocyte projection
0.35	GO:0016324	apical plasma membrane
0.35	GO:0043025	neuronal cell body
0.35	GO:0030424	axon
0.34	GO:0009986	cell surface
0.33	GO:0005634	nucleus
0.33	GO:0005789	endoplasmic reticulum membrane

sp|P57796|CABP4_HUMAN
Calcium-binding protein 4
Search

CABP4

0.91	Calcium-binding protein 4

0.65	GO:0007601	visual perception
0.63	GO:0060040	retinal bipolar neuron differentiation
0.62	GO:0008594	photoreceptor cell morphogenesis
0.62	GO:0046549	retinal cone cell development
0.56	GO:0065009	regulation of molecular function
0.56	GO:0007602	phototransduction
0.32	GO:0035556	intracellular signal transduction
0.32	GO:0006468	protein phosphorylation

0.71	GO:0005246	calcium channel regulator activity
0.70	GO:0005509	calcium ion binding
0.59	GO:0044325	ion channel binding
0.32	GO:0004674	protein serine/threonine kinase activity
0.31	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.52	GO:0005829	cytosol
0.36	GO:0043195	terminal bouton
0.34	GO:0005576	extracellular region
0.33	GO:0005794	Golgi apparatus
0.32	GO:0005886	plasma membrane

0.32

GO:0004674

sp|P58004|SESN2_HUMAN
Sestrin-2
Search

SESN2

0.91	Sestrin-2 isoform A

0.85	GO:1901031	regulation of response to reactive oxygen species
0.64	GO:1904262	negative regulation of TORC1 signaling
0.63	GO:0034198	cellular response to amino acid starvation
0.62	GO:0042149	cellular response to glucose starvation
0.62	GO:1902010	negative regulation of translation in response to endoplasmic reticulum stress
0.62	GO:0071230	cellular response to amino acid stimulus
0.61	GO:0032868	response to insulin
0.59	GO:0090526	regulation of gluconeogenesis involved in cellular glucose homeostasis
0.59	GO:0043201	response to leucine
0.59	GO:0036091	positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress

0.60	GO:0070728	leucine binding
0.58	GO:0032542	sulfiredoxin activity
0.54	GO:0005092	GDP-dissociation inhibitor activity
0.50	GO:0016684	oxidoreductase activity, acting on peroxide as acceptor
0.35	GO:0005515	protein binding

0.64	GO:0061700	GATOR2 complex
0.61	GO:0005634	nucleus
0.60	GO:0031932	TORC2 complex
0.57	GO:1990316	Atg1/ULK1 kinase complex
0.56	GO:0031588	nucleotide-activated protein kinase complex
0.44	GO:0005739	mitochondrion
0.34	GO:0005829	cytosol

0.58

EC:1.8.98.2

GO:0032542

sp|P58005|SESN3_HUMAN
Sestrin-3
Search

SESN3

0.90

Sestrin-3

0.85	GO:1901031	regulation of response to reactive oxygen species
0.60	GO:1904262	negative regulation of TORC1 signaling
0.59	GO:0034198	cellular response to amino acid starvation
0.59	GO:0042149	cellular response to glucose starvation
0.58	GO:0071230	cellular response to amino acid stimulus
0.57	GO:0032868	response to insulin
0.55	GO:0038203	TORC2 signaling
0.55	GO:0042593	glucose homeostasis
0.55	GO:0046626	regulation of insulin receptor signaling pathway
0.54	GO:0051896	regulation of protein kinase B signaling

0.46	GO:0070728	leucine binding
0.45	GO:0032542	sulfiredoxin activity
0.43	GO:0005092	GDP-dissociation inhibitor activity
0.41	GO:0016684	oxidoreductase activity, acting on peroxide as acceptor
0.35	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.60	GO:0061700	GATOR2 complex
0.56	GO:0031932	TORC2 complex
0.44	GO:1990316	Atg1/ULK1 kinase complex
0.44	GO:0031588	nucleotide-activated protein kinase complex
0.38	GO:0005739	mitochondrion
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.45

EC:1.8.98.2

GO:0032542

sp|P58012|FOXL2_HUMAN
Forkhead box protein L2
Search

FOXL2

0.77	Forkhead transcription factor Foxl2

0.62	GO:0002074	extraocular skeletal muscle development
0.60	GO:0019101	female somatic sex determination
0.59	GO:0006309	apoptotic DNA fragmentation
0.59	GO:0001541	ovarian follicle development
0.58	GO:0060014	granulosa cell differentiation
0.57	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:0010468	regulation of gene expression
0.56	GO:0046881	positive regulation of follicle-stimulating hormone secretion

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.59	GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process
0.54	GO:0031624	ubiquitin conjugating enzyme binding
0.54	GO:0030331	estrogen receptor binding
0.50	GO:0001012	RNA polymerase II regulatory region DNA binding
0.47	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.55	GO:0045171	intercellular bridge
0.35	GO:0043233	organelle lumen
0.34	GO:0044446	intracellular organelle part

sp|P58062|ISK7_HUMAN
Serine protease inhibitor Kazal-type 7
Search

SPINK7

0.97	Serine protease inhibitor Kazal-type 7

0.66	GO:1900004	negative regulation of serine-type endopeptidase activity
0.64	GO:0060046	regulation of acrosome reaction
0.56	GO:0043113	receptor clustering
0.54	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway
0.47	GO:0006508	proteolysis
0.40	GO:0006898	receptor-mediated endocytosis
0.39	GO:0007158	neuron cell-cell adhesion
0.38	GO:0007417	central nervous system development
0.38	GO:0001941	postsynaptic membrane organization
0.38	GO:0099601	regulation of neurotransmitter receptor activity

0.61	GO:0004867	serine-type endopeptidase inhibitor activity
0.55	GO:0043236	laminin binding
0.51	GO:0005509	calcium ion binding
0.47	GO:0008233	peptidase activity
0.42	GO:0005044	scavenger receptor activity
0.39	GO:0099602	neurotransmitter receptor regulator activity
0.38	GO:0002162	dystroglycan binding
0.37	GO:0005539	glycosaminoglycan binding
0.37	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity
0.37	GO:0033691	sialic acid binding

0.61	GO:0001669	acrosomal vesicle
0.56	GO:0005615	extracellular space
0.42	GO:0005605	basal lamina
0.42	GO:0005886	plasma membrane
0.38	GO:0045178	basal part of cell
0.38	GO:0031594	neuromuscular junction
0.37	GO:0030424	axon
0.36	GO:0005829	cytosol
0.35	GO:0098857	membrane microdomain
0.35	GO:0030054	cell junction

0.47

GO:0008233

sp|P58107|EPIPL_HUMAN
Epiplakin
Search

0.10

Epiplakin

0.44	GO:0031581	hemidesmosome assembly
0.42	GO:1905041	regulation of epithelium regeneration
0.42	GO:0051548	negative regulation of keratinocyte migration
0.41	GO:0010839	negative regulation of keratinocyte proliferation
0.41	GO:0045109	intermediate filament organization
0.40	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing
0.40	GO:0061045	negative regulation of wound healing
0.39	GO:0030856	regulation of epithelial cell differentiation
0.33	GO:0007565	female pregnancy
0.33	GO:0007584	response to nutrient

0.64	GO:0008092	cytoskeletal protein binding
0.42	GO:0045296	cadherin binding
0.41	GO:0019215	intermediate filament binding
0.35	GO:0008307	structural constituent of muscle
0.33	GO:0003723	RNA binding
0.33	GO:0047485	protein N-terminus binding
0.33	GO:0005200	structural constituent of cytoskeleton

0.69	GO:0005856	cytoskeleton
0.48	GO:0030056	hemidesmosome
0.45	GO:0005903	brush border
0.44	GO:0043292	contractile fiber
0.43	GO:0042383	sarcolemma
0.42	GO:0097356	perinucleolar compartment
0.42	GO:0005925	focal adhesion
0.41	GO:0016327	apicolateral plasma membrane
0.40	GO:0016323	basolateral plasma membrane
0.40	GO:0045178	basal part of cell

sp|P58166|INHBE_HUMAN
Inhibin beta E chain
Search

INHBE

0.96	Inhibin beta E subunit

0.76	GO:0010469	regulation of receptor activity
0.57	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
0.57	GO:0060395	SMAD protein signal transduction
0.53	GO:0043408	regulation of MAPK cascade
0.51	GO:0048468	cell development
0.51	GO:0042981	regulation of apoptotic process

0.78	GO:0008083	growth factor activity
0.77	GO:0005179	hormone activity
0.57	GO:0005160	transforming growth factor beta receptor binding
0.54	GO:0005125	cytokine activity

0.66	GO:0005576	extracellular region
0.35	GO:0031982	vesicle
0.30	GO:0016021	integral component of membrane

sp|P58170|OR1D5_HUMAN
Olfactory receptor 1D5
Search

0.44	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.38	GO:0000060	protein import into nucleus, translocation
0.34	GO:0007338	single fertilization
0.34	GO:0006935	chemotaxis

0.76	GO:0004984	olfactory receptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.36	GO:0042802	identical protein binding
0.33	GO:0005549	odorant binding

0.55	GO:0005886	plasma membrane
0.32	GO:0005622	intracellular
0.30	GO:0031224	intrinsic component of membrane

sp|P58173|OR2B6_HUMAN
Olfactory receptor 2B6
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.72	GO:0004930	G-protein coupled receptor activity
0.34	GO:0046982	protein heterodimerization activity
0.32	GO:0003677	DNA binding

0.55	GO:0005886	plasma membrane
0.34	GO:0000786	nucleosome
0.33	GO:0005938	cell cortex
0.33	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|P58180|OR4D2_HUMAN
Olfactory receptor 4D2
Search

0.40	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.33	GO:0006952	defense response
0.33	GO:0006979	response to oxidative stress
0.33	GO:0098869	cellular oxidant detoxification
0.32	GO:0055114	oxidation-reduction process

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.33	GO:0004601	peroxidase activity
0.33	GO:0020037	heme binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.33	EC:1.11.1.7	GO:0004601
0.33	KEGG:R03532	GO:0004601

sp|P58181|O10A3_HUMAN
Olfactory receptor 10A3
Search

0.46	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway

0.75	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity
0.39	GO:0005549	odorant binding

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P58182|O12D2_HUMAN
Olfactory receptor 12D2
Search

0.45	Olfactory receptor

0.76	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.72	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.35	GO:0005938	cell cortex
0.30	GO:0031224	intrinsic component of membrane

sp|P58215|LOXL3_HUMAN
Lysyl oxidase homolog 3
Search

LOXL3

0.85	Lysyl oxidase like protein 3

0.71	GO:0006898	receptor-mediated endocytosis
0.68	GO:0018057	peptidyl-lysine oxidation
0.66	GO:1905590	fibronectin fibril organization
0.65	GO:2000329	negative regulation of T-helper 17 cell lineage commitment
0.63	GO:2001046	positive regulation of integrin-mediated signaling pathway
0.62	GO:0001837	epithelial to mesenchymal transition
0.60	GO:0060021	palate development
0.59	GO:0021510	spinal cord development
0.59	GO:0061053	somite development
0.59	GO:0030324	lung development

0.80	GO:0005044	scavenger receptor activity
0.76	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor
0.71	GO:0005507	copper ion binding
0.62	GO:0001968	fibronectin binding
0.46	GO:0140096	catalytic activity, acting on a protein
0.43	GO:0070492	oligosaccharide binding
0.35	GO:0003909	DNA ligase activity

0.55	GO:0005615	extracellular space
0.48	GO:0005634	nucleus
0.41	GO:0005737	cytoplasm
0.40	GO:0000785	chromatin
0.39	GO:0012505	endomembrane system
0.38	GO:0043233	organelle lumen
0.38	GO:0043235	receptor complex
0.38	GO:0005604	basement membrane
0.30	GO:0016020	membrane

0.76

EC:1.4.3

GO:0016641

sp|P58294|PROK1_HUMAN
Prokineticin-1
Search

PROK1

0.97	Prokineticin

0.79	GO:0000187	activation of MAPK activity
0.76	GO:0045765	regulation of angiogenesis
0.74	GO:0008284	positive regulation of cell proliferation
0.67	GO:0007623	circadian rhythm
0.54	GO:0001525	angiogenesis
0.53	GO:0045987	positive regulation of smooth muscle contraction
0.51	GO:0008283	cell proliferation
0.49	GO:0007283	spermatogenesis
0.49	GO:0043066	negative regulation of apoptotic process
0.46	GO:0006935	chemotaxis

0.62	GO:0001664	G-protein coupled receptor binding
0.43	GO:0008083	growth factor activity
0.43	GO:0090729	toxin activity
0.36	GO:0070001	aspartic-type peptidase activity
0.35	GO:0004175	endopeptidase activity

0.64	GO:0005576	extracellular region
0.30	GO:0005623	cell

sp|P58304|VSX2_HUMAN
Visual system homeobox 2
Search

VSX2

0.92	Visual system homeobox 2

0.63	GO:0007275	multicellular organism development
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.41	GO:0007601	visual perception
0.37	GO:0030154	cell differentiation
0.37	GO:0009653	anatomical structure morphogenesis
0.36	GO:0006351	transcription, DNA-templated
0.36	GO:0048523	negative regulation of cellular process
0.36	GO:0050896	response to stimulus

0.63	GO:0043565	sequence-specific DNA binding
0.36	GO:0003682	chromatin binding
0.36	GO:0044212	transcription regulatory region DNA binding
0.34	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.32	GO:0005737	cytoplasm

sp|P58317|ZN121_HUMAN
Zinc finger protein 121
Search

0.65	zinc finger protein 25

0.51	GO:1903506	regulation of nucleic acid-templated transcription
0.51	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.51	GO:0010468	regulation of gene expression
0.39	GO:0060443	mammary gland morphogenesis
0.39	GO:0048286	lung alveolus development
0.39	GO:0010453	regulation of cell fate commitment
0.38	GO:0006383	transcription by RNA polymerase III
0.37	GO:0006366	transcription by RNA polymerase II
0.37	GO:1902679	negative regulation of RNA biosynthetic process

0.51	GO:0003676	nucleic acid binding
0.48	GO:0046872	metal ion binding
0.41	GO:0003700	DNA binding transcription factor activity
0.35	GO:0005515	protein binding

0.41	GO:0005622	intracellular
0.37	GO:0043227	membrane-bounded organelle

sp|P58335|ANTR2_HUMAN
Anthrax toxin receptor 2
Search

ANTXR2

0.93	Anthrax toxin receptor

0.53	GO:1901998	toxin transport
0.49	GO:0022414	reproductive process
0.42	GO:0000132	establishment of mitotic spindle orientation
0.33	GO:0043043	peptide biosynthetic process
0.32	GO:0044267	cellular protein metabolic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process

0.64	GO:0004872	receptor activity
0.50	GO:0046872	metal ion binding
0.40	GO:0017048	Rho GTPase binding
0.40	GO:0003779	actin binding
0.33	GO:0003735	structural constituent of ribosome

0.54	GO:0009897	external side of plasma membrane
0.42	GO:0032154	cleavage furrow
0.42	GO:0070938	contractile ring
0.42	GO:0030496	midbody
0.41	GO:0030864	cortical actin cytoskeleton
0.41	GO:0005768	endosome
0.35	GO:0044433	cytoplasmic vesicle part
0.34	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0098805	whole membrane
0.34	GO:0098588	bounding membrane of organelle

sp|P58340|MLF1_HUMAN
Myeloid leukemia factor 1
Search

MLF1

0.97	Myeloid leukemia factor 1

0.83	GO:0007050	cell cycle arrest
0.58	GO:0002318	myeloid progenitor cell differentiation
0.43	GO:0006351	transcription, DNA-templated
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.75	GO:0019904	protein domain specific binding
0.42	GO:0003677	DNA binding
0.35	GO:0003924	GTPase activity
0.35	GO:0032550	purine ribonucleoside binding
0.35	GO:0019001	guanyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.45	GO:0005634	nucleus
0.45	GO:0097730	non-motile cilium
0.44	GO:0031514	motile cilium
0.41	GO:0097546	ciliary base
0.39	GO:0005737	cytoplasm

sp|P58397|ATS12_HUMAN
A disintegrin and metalloproteinase with thrombospondin motifs 12
Search

ADAMTS7

0.79	A disintegrin and metalloproteinase with thrombospondin motifs 7

0.66	GO:0007229	integrin-mediated signaling pathway
0.60	GO:0006508	proteolysis
0.56	GO:0032331	negative regulation of chondrocyte differentiation
0.55	GO:0071347	cellular response to interleukin-1
0.54	GO:0071773	cellular response to BMP stimulus
0.54	GO:0071356	cellular response to tumor necrosis factor
0.53	GO:1902203	negative regulation of hepatocyte growth factor receptor signaling pathway
0.53	GO:2001112	regulation of cellular response to hepatocyte growth factor stimulus
0.52	GO:1901509	regulation of endothelial tube morphogenesis
0.52	GO:0030167	proteoglycan catabolic process

0.69	GO:0004222	metalloendopeptidase activity
0.53	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding

0.59	GO:0005576	extracellular region
0.46	GO:0009986	cell surface
0.37	GO:0005788	endoplasmic reticulum lumen

0.69

GO:0004222

sp|P58417|NXPH1_HUMAN
Neurexophilin-1
Search

NXPH1

0.91	Neurexophilin

0.36

GO:0007218

neuropeptide signaling pathway

0.71

GO:0005102

receptor binding

0.45	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

sp|P58418|CLRN1_HUMAN
Clarin-1
Search

CLRN1

0.97	LOW QUALITY PROTEIN: clarin-1

0.63	GO:0050885	neuromuscular process controlling balance
0.61	GO:0060088	auditory receptor cell stereocilium organization
0.60	GO:0007605	sensory perception of sound
0.57	GO:0010592	positive regulation of lamellipodium assembly
0.56	GO:0045494	photoreceptor cell maintenance
0.52	GO:0050953	sensory perception of light stimulus
0.50	GO:0007015	actin filament organization
0.49	GO:0048870	cell motility
0.47	GO:0036466	synaptic vesicle recycling via endosome
0.46	GO:0035418	protein localization to synapse

0.62	GO:0032421	stereocilium bundle
0.59	GO:0045178	basal part of cell
0.57	GO:0098858	actin-based cell projection
0.57	GO:0030140	trans-Golgi network transport vesicle
0.55	GO:0043005	neuron projection
0.54	GO:0030027	lamellipodium
0.52	GO:0005874	microtubule
0.45	GO:0035869	ciliary transition zone
0.42	GO:0045202	synapse
0.42	GO:0005886	plasma membrane

sp|P58499|FAM3B_HUMAN
Protein FAM3B
Search

sp|P58505|CU058_HUMAN
Uncharacterized protein C21orf58
Search

0.40	GO:0007018	microtubule-based movement
0.39	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.39	GO:1903506	regulation of nucleic acid-templated transcription
0.39	GO:0010468	regulation of gene expression

0.44	GO:0005515	protein binding
0.42	GO:0071949	FAD binding
0.40	GO:0003777	microtubule motor activity
0.37	GO:0003676	nucleic acid binding
0.36	GO:0005509	calcium ion binding
0.36	GO:0030554	adenyl nucleotide binding
0.35	GO:0032555	purine ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.40	GO:0016459	myosin complex
0.30	GO:0044425	membrane part

sp|P58511|SI11A_HUMAN
Small integral membrane protein 11A
Search

0.97	small integral membrane protein 11

0.35

GO:0071805

potassium ion transmembrane transport

0.35

GO:0005249

voltage-gated potassium channel activity

0.30

GO:0016021

integral component of membrane

sp|P58512|CU067_HUMAN
Uncharacterized protein encoded by LINC01547
Search

sp|P58513|CU042_HUMAN
Putative uncharacterized protein encoded by LINC00158
Search

sp|P58546|MTPN_HUMAN
Myotrophin
Search

MTPN

0.96	Myotrophin

0.80	GO:0014742	positive regulation of muscle hypertrophy
0.79	GO:0010611	regulation of cardiac muscle hypertrophy
0.78	GO:2000812	regulation of barbed-end actin filament capping
0.73	GO:0008361	regulation of cell size
0.52	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.51	GO:0030307	positive regulation of cell growth
0.49	GO:0021684	cerebellar granular layer formation
0.48	GO:0043403	skeletal muscle tissue regeneration
0.48	GO:0021533	cell differentiation in hindbrain
0.47	GO:0051247	positive regulation of protein metabolic process

0.46	GO:0002039	p53 binding
0.44	GO:0018024	histone-lysine N-methyltransferase activity
0.41	GO:0043565	sequence-specific DNA binding
0.39	GO:0008270	zinc ion binding
0.37	GO:0019901	protein kinase binding
0.36	GO:0008318	protein prenyltransferase activity
0.34	GO:0008081	phosphoric diester hydrolase activity

0.74	GO:0008290	F-actin capping protein complex
0.51	GO:0048471	perinuclear region of cytoplasm
0.50	GO:0030424	axon
0.47	GO:0005634	nucleus
0.45	GO:0005829	cytosol
0.41	GO:0070062	extracellular exosome
0.40	GO:0005694	chromosome
0.33	GO:0005783	endoplasmic reticulum
0.30	GO:0016020	membrane

0.44

EC:2.1.1.43

GO:0018024

sp|P58549|FXYD7_HUMAN
FXYD domain-containing ion transport regulator 7
Search

FXYD7

0.66	FXYD domain-containing ion transport regulator

0.60	GO:0034220	ion transmembrane transport
0.59	GO:2000649	regulation of sodium ion transmembrane transporter activity
0.41	GO:1903779	regulation of cardiac conduction
0.36	GO:0006813	potassium ion transport
0.36	GO:1903278	positive regulation of sodium ion export across plasma membrane
0.36	GO:0086036	regulation of cardiac muscle cell membrane potential
0.36	GO:0050790	regulation of catalytic activity
0.35	GO:0006814	sodium ion transport
0.35	GO:0098739	import across plasma membrane
0.35	GO:0140115	export across plasma membrane

0.70	GO:0005216	ion channel activity
0.59	GO:0017080	sodium channel regulator activity
0.50	GO:0051117	ATPase binding
0.35	GO:0015079	potassium ion transmembrane transporter activity
0.34	GO:0015662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
0.34	GO:0015081	sodium ion transmembrane transporter activity
0.34	GO:0019829	cation-transporting ATPase activity

0.46	GO:0005887	integral component of plasma membrane
0.36	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0042383	sarcolemma
0.35	GO:0090533	cation-transporting ATPase complex

sp|P58550|FXYD8_HUMAN
Putative FXYD domain-containing ion transport regulator 8
Search

FXYD6

0.85	FXYD domain-containing ion transport regulator

0.60	GO:0034220	ion transmembrane transport
0.53	GO:2000649	regulation of sodium ion transmembrane transporter activity
0.37	GO:1903779	regulation of cardiac conduction
0.35	GO:1903275	positive regulation of sodium ion export
0.35	GO:1903276	regulation of sodium ion export across plasma membrane
0.35	GO:0086036	regulation of cardiac muscle cell membrane potential

0.70	GO:0005216	ion channel activity
0.53	GO:0017080	sodium channel regulator activity
0.34	GO:0005515	protein binding

0.44	GO:0005887	integral component of plasma membrane
0.34	GO:0042383	sarcolemma

sp|P58557|YBEY_HUMAN
Putative ribonuclease
Search

YBEY

0.42	Endoribonuclease YbeY

0.69	GO:0006364	rRNA processing
0.61	GO:0006508	proteolysis
0.44	GO:0090305	nucleic acid phosphodiester bond hydrolysis

0.70	GO:0004222	metalloendopeptidase activity
0.45	GO:0004519	endonuclease activity
0.43	GO:0004540	ribonuclease activity
0.41	GO:0008270	zinc ion binding

0.52	GO:0005634	nucleus
0.52	GO:0005739	mitochondrion

0.70

GO:0004222

sp|P58658|EVA1C_HUMAN
Protein eva-1 homolog C
Search

EVA1C

0.93	Eva-1 homolog C (C. elegans)

0.69	GO:0030246	carbohydrate binding
0.57	GO:0008201	heparin binding

0.48	GO:0005576	extracellular region
0.34	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|P58743|S26A5_HUMAN
Prestin
Search

SLC26A5

0.96

Prestin

0.82	GO:0007605	sensory perception of sound
0.75	GO:1902358	sulfate transmembrane transport
0.61	GO:0008360	regulation of cell shape
0.53	GO:0042391	regulation of membrane potential
0.50	GO:0019532	oxalate transport
0.49	GO:0015701	bicarbonate transport
0.47	GO:0051453	regulation of intracellular pH
0.46	GO:0006821	chloride transport
0.40	GO:0035864	response to potassium ion
0.39	GO:1902074	response to salt

0.78	GO:0008271	secondary active sulfate transmembrane transporter activity
0.54	GO:0030507	spectrin binding
0.50	GO:0019531	oxalate transmembrane transporter activity
0.49	GO:0015106	bicarbonate transmembrane transporter activity
0.49	GO:0015301	anion:anion antiporter activity
0.45	GO:0005254	chloride channel activity
0.37	GO:0042803	protein homodimerization activity
0.37	GO:0008134	transcription factor binding
0.35	GO:0070325	lipoprotein particle receptor binding
0.34	GO:0003774	motor activity

0.54	GO:0016328	lateral plasma membrane
0.53	GO:0016323	basolateral plasma membrane
0.42	GO:0005887	integral component of plasma membrane
0.34	GO:0005737	cytoplasm

sp|P58753|TIRAP_HUMAN
Toll/interleukin-1 receptor domain-containing adapter protein
Search

TIRAP

0.95	Toll-interleukin 1 receptor (TIR) domain containing adaptor protein

0.78	GO:0035665	TIRAP-dependent toll-like receptor 4 signaling pathway
0.78	GO:0032738	positive regulation of interleukin-15 production
0.76	GO:0034137	positive regulation of toll-like receptor 2 signaling pathway
0.75	GO:0090073	positive regulation of protein homodimerization activity
0.75	GO:0034145	positive regulation of toll-like receptor 4 signaling pathway
0.74	GO:0070935	3'-UTR-mediated mRNA stabilization
0.74	GO:0045410	positive regulation of interleukin-6 biosynthetic process
0.73	GO:0007250	activation of NF-kappaB-inducing kinase activity
0.72	GO:0032757	positive regulation of interleukin-8 production
0.71	GO:0032760	positive regulation of tumor necrosis factor production

0.77	GO:0035663	Toll-like receptor 2 binding
0.75	GO:0035662	Toll-like receptor 4 binding
0.72	GO:0005080	protein kinase C binding
0.62	GO:0046982	protein heterodimerization activity
0.62	GO:0042802	identical protein binding

0.49	GO:0005886	plasma membrane
0.44	GO:0005737	cytoplasm

sp|P58872|RHBL3_HUMAN
Rhomboid-related protein 3
Search

RHBDL3

0.73	Rhomboid-like protein (Fragment)

0.61	GO:0006508	proteolysis
0.43	GO:0051604	protein maturation
0.34	GO:0043547	positive regulation of GTPase activity

0.69	GO:0004252	serine-type endopeptidase activity
0.62	GO:0005509	calcium ion binding
0.35	GO:1902936	phosphatidylinositol bisphosphate binding
0.34	GO:0005096	GTPase activator activity
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032553	ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.30

GO:0031224

intrinsic component of membrane

0.69

GO:0004252

sp|P58876|H2B1D_HUMAN
Histone H2B type 1-D
Search

0.92	Histone H2B type 1-M

0.53	GO:0006334	nucleosome assembly
0.38	GO:0002227	innate immune response in mucosa
0.38	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.37	GO:0019731	antibacterial humoral response
0.37	GO:0050830	defense response to Gram-positive bacterium
0.35	GO:0016567	protein ubiquitination
0.33	GO:0006352	DNA-templated transcription, initiation

0.74	GO:0046982	protein heterodimerization activity
0.54	GO:0003677	DNA binding
0.40	GO:0097677	STAT family protein binding
0.38	GO:0044389	ubiquitin-like protein ligase binding
0.36	GO:0042802	identical protein binding

0.74	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.45	GO:0005829	cytosol
0.45	GO:0031974	membrane-enclosed lumen
0.38	GO:0005615	extracellular space
0.38	GO:1903561	extracellular vesicle
0.35	GO:0043234	protein complex

sp|P59020|DSCR9_HUMAN
Down syndrome critical region protein 9
Search

sp|P59022|DSC10_HUMAN
Down syndrome critical region protein 10
Search

DSCR10

0.93	Down syndrome critical region protein 10

sp|P59025|RTP1_HUMAN
Receptor-transporting protein 1
Search

RTP1

0.97	Receptor-transporting protein 1 short

0.65	GO:0051205	protein insertion into membrane
0.58	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste
0.52	GO:0006612	protein targeting to membrane
0.34	GO:0010469	regulation of receptor activity

0.78	GO:0031849	olfactory receptor binding
0.35	GO:0005179	hormone activity

0.64	GO:0009986	cell surface
0.37	GO:0005622	intracellular
0.37	GO:0005886	plasma membrane
0.34	GO:0005576	extracellular region
0.30	GO:0044425	membrane part

sp|P59036|CU082_HUMAN
Putative uncharacterized protein encoded by LINC00310
Search

sp|P59037|CU084_HUMAN
Putative uncharacterized protein encoded by LINC00313
Search

sp|P59044|NLRP6_HUMAN
NACHT, LRR and PYD domains-containing protein 6
Search

NLRP6

0.96	NLR family pyrin domain-containing protein 6

0.72	GO:0002862	negative regulation of inflammatory response to antigenic stimulus
0.72	GO:0070255	regulation of mucus secretion
0.71	GO:0034122	negative regulation of toll-like receptor signaling pathway
0.70	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling
0.69	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.65	GO:0042060	wound healing
0.64	GO:0009617	response to bacterium
0.61	GO:0010506	regulation of autophagy
0.41	GO:0050704	regulation of interleukin-1 secretion
0.41	GO:2000318	positive regulation of T-helper 17 type immune response

0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0008144	drug binding
0.36	GO:0042802	identical protein binding
0.36	GO:0008134	transcription factor binding
0.35	GO:0043565	sequence-specific DNA binding
0.34	GO:0003924	GTPase activity
0.34	GO:0016887	ATPase activity

0.38	GO:0072559	NLRP3 inflammasome complex
0.35	GO:0019897	extrinsic component of plasma membrane
0.34	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

0.34

GO:0016887

sp|P59045|NAL11_HUMAN
NACHT, LRR and PYD domains-containing protein 11
Search

NLRP11

0.97	NACHT, LRR and PYD domains-containing protein 11

0.55	GO:0042981	regulation of apoptotic process
0.54	GO:0006954	inflammatory response
0.53	GO:0050704	regulation of interleukin-1 secretion
0.52	GO:2000116	regulation of cysteine-type endopeptidase activity
0.51	GO:0032731	positive regulation of interleukin-1 beta production
0.51	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.51	GO:0045087	innate immune response
0.51	GO:0010950	positive regulation of endopeptidase activity
0.50	GO:0032692	negative regulation of interleukin-1 production
0.50	GO:0051222	positive regulation of protein transport

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.43	GO:0005515	protein binding
0.39	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process
0.37	GO:0043565	sequence-specific DNA binding
0.30	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.30	GO:0004497	monooxygenase activity
0.30	GO:0003723	RNA binding

0.50	GO:0061702	inflammasome complex
0.41	GO:0005634	nucleus
0.38	GO:0000781	chromosome, telomeric region
0.38	GO:0070013	intracellular organelle lumen
0.37	GO:0012505	endomembrane system
0.37	GO:0043025	neuronal cell body
0.33	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.30

GO:0016705

sp|P59046|NAL12_HUMAN
NACHT, LRR and PYD domains-containing protein 12
Search

NLRP3

0.73	NACHT LRR and PYD domain-containing protein 3

0.58	GO:0050711	negative regulation of interleukin-1 secretion
0.56	GO:0042345	regulation of NF-kappaB import into nucleus
0.55	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling
0.55	GO:0002674	negative regulation of acute inflammatory response
0.55	GO:0032088	negative regulation of NF-kappaB transcription factor activity
0.54	GO:0050718	positive regulation of interleukin-1 beta secretion
0.54	GO:0032691	negative regulation of interleukin-1 beta production
0.54	GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.53	GO:0090317	negative regulation of intracellular protein transport
0.53	GO:0042992	negative regulation of transcription factor import into nucleus

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.48	GO:0042802	identical protein binding
0.44	GO:0008134	transcription factor binding
0.42	GO:0043565	sequence-specific DNA binding
0.34	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process
0.34	GO:0019904	protein domain specific binding
0.33	GO:0019899	enzyme binding

0.56	GO:0072559	NLRP3 inflammasome complex
0.41	GO:0005634	nucleus
0.38	GO:0005783	endoplasmic reticulum
0.38	GO:0005576	extracellular region
0.35	GO:0072558	NLRP1 inflammasome complex
0.33	GO:0043233	organelle lumen
0.32	GO:0044446	intracellular organelle part

sp|P59047|NALP5_HUMAN
NACHT, LRR and PYD domains-containing protein 5
Search

NLRP5

0.94	NACHT, LRR and PYD domains-containing protein 5

0.56	GO:0070997	neuron death
0.44	GO:0050704	regulation of interleukin-1 secretion
0.44	GO:0008588	release of cytoplasmic sequestered NF-kappaB
0.44	GO:0045345	positive regulation of MHC class I biosynthetic process
0.44	GO:0045751	negative regulation of Toll signaling pathway
0.44	GO:0045409	negative regulation of interleukin-6 biosynthetic process
0.43	GO:0031953	negative regulation of protein autophosphorylation
0.43	GO:0032692	negative regulation of interleukin-1 production
0.43	GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.43	GO:0050710	negative regulation of cytokine secretion

0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0008144	drug binding
0.36	GO:0005515	protein binding
0.35	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process
0.35	GO:0003924	GTPase activity
0.34	GO:0016887	ATPase activity
0.31	GO:0003676	nucleic acid binding

0.41	GO:0005730	nucleolus
0.41	GO:0042585	germinal vesicle
0.40	GO:0005938	cell cortex
0.39	GO:0005829	cytosol
0.38	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0005739	mitochondrion
0.36	GO:0045177	apical part of cell
0.36	GO:0019897	extrinsic component of plasma membrane
0.35	GO:0043234	protein complex
0.35	GO:0005654	nucleoplasm

0.34

GO:0016887

sp|P59051|BRAS2_HUMAN
Putative uncharacterized protein encoded by BRWD1-AS2
Search

sp|P59052|B3AS1_HUMAN
Putative uncharacterized protein B3GALT5-AS1
Search

sp|P59074|CHM4P_HUMAN
Putative charged multivesicular body protein 4B-like protein CHMP4BP1
Search

CHMP4B

0.92	Charged multivesicular body protein 4Bb

0.79	GO:0007034	vacuolar transport
0.56	GO:0036438	maintenance of lens transparency
0.56	GO:0090611	ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway
0.56	GO:0090148	membrane fission
0.55	GO:0010458	exit from mitosis
0.55	GO:0031468	nuclear envelope reassembly
0.55	GO:1902902	negative regulation of autophagosome assembly
0.55	GO:1902188	positive regulation of viral release from host cell
0.54	GO:1901673	regulation of mitotic spindle assembly
0.54	GO:0000920	cell separation after cytokinesis

0.51	GO:0045296	cadherin binding
0.49	GO:0042803	protein homodimerization activity
0.33	GO:0003700	DNA binding transcription factor activity

0.55	GO:0000815	ESCRT III complex
0.53	GO:0030496	midbody
0.50	GO:0005635	nuclear envelope
0.49	GO:0009898	cytoplasmic side of plasma membrane
0.49	GO:0048475	coated membrane
0.46	GO:0005829	cytosol
0.41	GO:0031902	late endosome membrane
0.34	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

sp|P59089|CU086_HUMAN
Putative uncharacterized protein encoded by LINC00205
Search

sp|P59090|TSAS2_HUMAN
Putative uncharacterized protein TSPEAR-AS2
Search

sp|P59091|CU093_HUMAN
Putative uncharacterized protein encoded by LINC00315
Search

sp|P59095|STAR6_HUMAN
StAR-related lipid transfer protein 6
Search

STARD6

0.97	StAR-related lipid transfer domain containing protein 6

0.53	GO:0010879	cholesterol transport involved in cholesterol storage
0.52	GO:1904253	positive regulation of bile acid metabolic process
0.51	GO:0070508	cholesterol import
0.51	GO:0010873	positive regulation of cholesterol esterification
0.51	GO:0070857	regulation of bile acid biosynthetic process
0.50	GO:0010893	positive regulation of steroid biosynthetic process
0.50	GO:0032367	intracellular cholesterol transport
0.45	GO:0031328	positive regulation of cellular biosynthetic process
0.38	GO:0034435	cholesterol esterification

0.72	GO:0008289	lipid binding
0.61	GO:0043178	alcohol binding
0.50	GO:0017127	cholesterol transporter activity
0.39	GO:0097159	organic cyclic compound binding
0.36	GO:0032052	bile acid binding

0.46	GO:0005739	mitochondrion
0.45	GO:0031410	cytoplasmic vesicle
0.35	GO:0005783	endoplasmic reticulum
0.35	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|P59103|DAOA_HUMAN
D-amino acid oxidase activator
Search

DAOA

0.96	D-amino acid oxidase activator

0.89	GO:1900758	negative regulation of D-amino-acid oxidase activity
0.57	GO:0043085	positive regulation of catalytic activity

0.58	GO:0008047	enzyme activator activity
0.56	GO:0019899	enzyme binding

0.61	GO:0048471	perinuclear region of cytoplasm
0.56	GO:0005794	Golgi apparatus
0.49	GO:0005739	mitochondrion

sp|P59190|RAB15_HUMAN
Ras-related protein Rab-15
Search

RAB15

0.92	Putative rab subfamily protein of small gtpase

0.54	GO:0017157	regulation of exocytosis
0.49	GO:1903532	positive regulation of secretion by cell
0.48	GO:0006904	vesicle docking involved in exocytosis
0.46	GO:0045046	protein import into peroxisome membrane
0.44	GO:0009306	protein secretion
0.43	GO:0019882	antigen processing and presentation
0.40	GO:0072659	protein localization to plasma membrane
0.37	GO:0009653	anatomical structure morphogenesis
0.37	GO:0051459	regulation of corticotropin secretion
0.37	GO:0006979	response to oxidative stress

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.45	GO:0019003	GDP binding
0.41	GO:0005102	receptor binding
0.38	GO:0004602	glutathione peroxidase activity
0.37	GO:0030911	TPR domain binding
0.34	GO:0071532	ankyrin repeat binding
0.34	GO:0032794	GTPase activating protein binding
0.32	GO:0046983	protein dimerization activity
0.31	GO:0016740	transferase activity

0.50	GO:0031410	cytoplasmic vesicle
0.49	GO:0098805	whole membrane
0.49	GO:0098588	bounding membrane of organelle
0.49	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0005929	cilium
0.45	GO:0012505	endomembrane system
0.43	GO:0044438	microbody part
0.43	GO:0016604	nuclear body
0.43	GO:0005777	peroxisome
0.40	GO:0098793	presynapse

0.38

EC:1.11.1.9

GO:0004602

sp|P59282|TPPP2_HUMAN
Tubulin polymerization-promoting protein family member 2
Search

TPPP2

0.95	Tubulin polymerization-promoting protein family member 2

0.73	GO:0001578	microtubule bundle formation
0.70	GO:0046785	microtubule polymerization
0.41	GO:0048675	axon extension
0.33	GO:0022900	electron transport chain

0.71	GO:0015631	tubulin binding
0.41	GO:0005509	calcium ion binding
0.36	GO:0019706	protein-cysteine S-palmitoyltransferase activity
0.33	GO:0020037	heme binding
0.33	GO:0009055	electron transfer activity

0.55	GO:0097427	microtubule bundle
0.50	GO:0048471	perinuclear region of cytoplasm
0.49	GO:0005829	cytosol
0.38	GO:0005874	microtubule
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.36

EC:2.3.1.225

GO:0019706

sp|P59510|ATS20_HUMAN
A disintegrin and metalloproteinase with thrombospondin motifs 20
Search

ADAMTS20

0.83	A disintegrin and metalloproteinase with thrombospondin motif 9

0.61	GO:0045636	positive regulation of melanocyte differentiation
0.61	GO:0006508	proteolysis
0.57	GO:0007229	integrin-mediated signaling pathway
0.55	GO:0030198	extracellular matrix organization
0.53	GO:0043066	negative regulation of apoptotic process
0.51	GO:0009967	positive regulation of signal transduction
0.42	GO:1990798	pancreas regeneration
0.41	GO:0031018	endocrine pancreas development
0.41	GO:0090673	endothelial cell-matrix adhesion
0.40	GO:1903671	negative regulation of sprouting angiogenesis

0.70	GO:0004222	metalloendopeptidase activity
0.61	GO:0008270	zinc ion binding

0.65	GO:0005576	extracellular region
0.38	GO:0009986	cell surface
0.38	GO:0005783	endoplasmic reticulum
0.30	GO:0016020	membrane

0.70

GO:0004222

sp|P59533|T2R38_HUMAN
Taste receptor type 2 member 38
Search

TAS2R38

0.68	Taste receptor type 2

0.85	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste
0.71	GO:0007186	G-protein coupled receptor signaling pathway

0.86	GO:0033038	bitter taste receptor activity
0.72	GO:0004930	G-protein coupled receptor activity

0.41	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|P59534|T2R39_HUMAN
Taste receptor type 2 member 39
Search

0.68	Taste receptor type 2

0.82	GO:0050909	sensory perception of taste
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.55	GO:0050907	detection of chemical stimulus involved in sensory perception

0.72	GO:0004930	G-protein coupled receptor activity
0.63	GO:0033038	bitter taste receptor activity

0.34	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|P59535|T2R40_HUMAN
Taste receptor type 2 member 40
Search

0.68	Taste receptor type 2

0.82	GO:0050909	sensory perception of taste
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.57	GO:0050907	detection of chemical stimulus involved in sensory perception

0.72	GO:0004930	G-protein coupled receptor activity
0.65	GO:0033038	bitter taste receptor activity

0.34	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|P59536|T2R41_HUMAN
Taste receptor type 2 member 41
Search

0.66	Taste receptor type 2

0.82	GO:0050909	sensory perception of taste
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.47	GO:0050907	detection of chemical stimulus involved in sensory perception

0.72	GO:0004930	G-protein coupled receptor activity
0.52	GO:0033038	bitter taste receptor activity
0.32	GO:0005515	protein binding

0.38	GO:0009897	external side of plasma membrane
0.38	GO:0005802	trans-Golgi network
0.36	GO:0005783	endoplasmic reticulum
0.30	GO:0031224	intrinsic component of membrane

sp|P59537|T2R43_HUMAN
Taste receptor type 2 member 43
Search

0.67	Taste receptor type 2

0.82	GO:0050909	sensory perception of taste
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.47	GO:0050907	detection of chemical stimulus involved in sensory perception

0.72	GO:0004930	G-protein coupled receptor activity
0.52	GO:0033038	bitter taste receptor activity

0.44	GO:0060170	ciliary membrane
0.40	GO:0031514	motile cilium
0.30	GO:0031224	intrinsic component of membrane

sp|P59538|T2R31_HUMAN
Taste receptor type 2 member 31
Search

0.67	Taste receptor type 2

0.82	GO:0050909	sensory perception of taste
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.47	GO:0050907	detection of chemical stimulus involved in sensory perception

0.72	GO:0004930	G-protein coupled receptor activity
0.52	GO:0033038	bitter taste receptor activity

0.44	GO:0060170	ciliary membrane
0.40	GO:0031514	motile cilium
0.30	GO:0031224	intrinsic component of membrane

sp|P59539|T2R45_HUMAN
Taste receptor type 2 member 45
Search

0.67	Taste receptor type 2

0.82	GO:0050909	sensory perception of taste
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.46	GO:0050907	detection of chemical stimulus involved in sensory perception

0.72	GO:0004930	G-protein coupled receptor activity
0.51	GO:0033038	bitter taste receptor activity

0.44	GO:0060170	ciliary membrane
0.39	GO:0031514	motile cilium
0.30	GO:0031224	intrinsic component of membrane

sp|P59540|T2R46_HUMAN
Taste receptor type 2 member 46
Search

0.67	Taste receptor type 2

0.82	GO:0050909	sensory perception of taste
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.47	GO:0050907	detection of chemical stimulus involved in sensory perception

0.72	GO:0004930	G-protein coupled receptor activity
0.52	GO:0033038	bitter taste receptor activity

0.45	GO:0060170	ciliary membrane
0.40	GO:0031514	motile cilium
0.30	GO:0031224	intrinsic component of membrane

sp|P59541|T2R30_HUMAN
Taste receptor type 2 member 30
Search

0.67	Taste receptor type 2

0.82	GO:0050909	sensory perception of taste
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.46	GO:0050907	detection of chemical stimulus involved in sensory perception

0.72	GO:0004930	G-protein coupled receptor activity
0.51	GO:0033038	bitter taste receptor activity

0.44	GO:0060170	ciliary membrane
0.39	GO:0031514	motile cilium
0.30	GO:0031224	intrinsic component of membrane

sp|P59542|T2R19_HUMAN
Taste receptor type 2 member 19
Search

0.67	Taste receptor type 2

0.82	GO:0050909	sensory perception of taste
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.46	GO:0050907	detection of chemical stimulus involved in sensory perception

0.72	GO:0004930	G-protein coupled receptor activity
0.51	GO:0033038	bitter taste receptor activity

0.43	GO:0060170	ciliary membrane
0.38	GO:0031514	motile cilium
0.30	GO:0031224	intrinsic component of membrane

sp|P59543|T2R20_HUMAN
Taste receptor type 2 member 20
Search

0.67	Taste receptor type 2

0.82	GO:0050909	sensory perception of taste
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.46	GO:0050907	detection of chemical stimulus involved in sensory perception

0.72	GO:0004930	G-protein coupled receptor activity
0.50	GO:0033038	bitter taste receptor activity

0.43	GO:0060170	ciliary membrane
0.39	GO:0031514	motile cilium
0.30	GO:0031224	intrinsic component of membrane

sp|P59544|T2R50_HUMAN
Taste receptor type 2 member 50
Search

0.68	Taste receptor type 2

0.82	GO:0050909	sensory perception of taste
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.48	GO:0050907	detection of chemical stimulus involved in sensory perception

0.72	GO:0004930	G-protein coupled receptor activity
0.53	GO:0033038	bitter taste receptor activity

0.39	GO:0031514	motile cilium
0.39	GO:0060170	ciliary membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P59551|T2R60_HUMAN
Taste receptor type 2 member 60
Search

0.64	Taste receptor type 2

0.82	GO:0050909	sensory perception of taste
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.48	GO:0050907	detection of chemical stimulus involved in sensory perception
0.35	GO:1904558	response to dextromethorphan
0.35	GO:1904560	response to diphenidol
0.35	GO:0072747	cellular response to chloramphenicol
0.35	GO:0080184	response to phenylpropanoid
0.35	GO:1902350	cellular response to chloroquine
0.35	GO:0071316	cellular response to nicotine
0.34	GO:1902656	calcium ion import into cytosol

0.72	GO:0004930	G-protein coupled receptor activity
0.53	GO:0033038	bitter taste receptor activity

0.35	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P59646|FXYD4_HUMAN
FXYD domain-containing ion transport regulator 4
Search

FXYD4

0.79	FXYD domain-containing ion transport regulator

0.60	GO:0034220	ion transmembrane transport
0.57	GO:2000649	regulation of sodium ion transmembrane transporter activity
0.47	GO:0050790	regulation of catalytic activity
0.44	GO:0006813	potassium ion transport
0.41	GO:1903779	regulation of cardiac conduction
0.40	GO:0006814	sodium ion transport
0.36	GO:0006821	chloride transport
0.30	GO:0009987	cellular process

0.70	GO:0005216	ion channel activity
0.67	GO:0051117	ATPase binding
0.58	GO:0017080	sodium channel regulator activity
0.40	GO:0015079	potassium ion transmembrane transporter activity
0.36	GO:0015108	chloride transmembrane transporter activity

0.48	GO:0005789	endoplasmic reticulum membrane
0.48	GO:0005887	integral component of plasma membrane
0.38	GO:0070062	extracellular exosome

sp|P59665|DEF1_HUMAN
Neutrophil defensin 1
Search

0.97	Myeloid alpha defensin 9

0.72	GO:0042742	defense response to bacterium
0.58	GO:0050832	defense response to fungus
0.55	GO:0031640	killing of cells of other organism
0.50	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.49	GO:0045087	innate immune response
0.46	GO:0002252	immune effector process
0.45	GO:0009615	response to virus
0.44	GO:0002385	mucosal immune response
0.44	GO:0030520	intracellular estrogen receptor signaling pathway
0.43	GO:1905710	positive regulation of membrane permeability

0.47

GO:0042803

protein homodimerization activity

0.73	GO:0005615	extracellular space
0.49	GO:0005766	primary lysosome
0.47	GO:0030141	secretory granule
0.47	GO:0005796	Golgi lumen
0.46	GO:0060205	cytoplasmic vesicle lumen
0.43	GO:0005775	vacuolar lumen
0.42	GO:1903561	extracellular vesicle
0.38	GO:0031012	extracellular matrix
0.37	GO:0030133	transport vesicle
0.30	GO:0031224	intrinsic component of membrane

sp|P59666|DEF3_HUMAN
Neutrophil defensin 3
Search

0.97	Myeloid alpha defensin 9

0.72	GO:0042742	defense response to bacterium
0.58	GO:0050832	defense response to fungus
0.55	GO:0031640	killing of cells of other organism
0.51	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.49	GO:0045087	innate immune response
0.46	GO:0002252	immune effector process
0.45	GO:0009615	response to virus
0.44	GO:0002385	mucosal immune response
0.44	GO:0030520	intracellular estrogen receptor signaling pathway
0.43	GO:1905710	positive regulation of membrane permeability

0.47

GO:0042803

protein homodimerization activity

0.73	GO:0005615	extracellular space
0.49	GO:0005766	primary lysosome
0.47	GO:0030141	secretory granule
0.47	GO:0005796	Golgi lumen
0.46	GO:0060205	cytoplasmic vesicle lumen
0.43	GO:0005775	vacuolar lumen
0.42	GO:1903561	extracellular vesicle
0.37	GO:0031012	extracellular matrix
0.37	GO:0030133	transport vesicle
0.30	GO:0031224	intrinsic component of membrane

sp|P59768|GBG2_HUMAN
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
Search

GNG2

0.71	Guanine nucleotide-binding protein subunit gamma

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.47	GO:0030308	negative regulation of cell growth
0.44	GO:0008283	cell proliferation
0.44	GO:0048010	vascular endothelial growth factor receptor signaling pathway
0.44	GO:0002040	sprouting angiogenesis
0.37	GO:0071380	cellular response to prostaglandin E stimulus
0.37	GO:0071417	cellular response to organonitrogen compound
0.36	GO:0071869	response to catecholamine
0.36	GO:0033762	response to glucagon
0.36	GO:0019933	cAMP-mediated signaling

0.64	GO:0004871	signal transducer activity
0.52	GO:0031681	G-protein beta-subunit binding
0.35	GO:0003924	GTPase activity

0.81	GO:1905360	GTPase complex
0.80	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.65	GO:0098797	plasma membrane protein complex
0.39	GO:0005829	cytosol
0.38	GO:0070062	extracellular exosome
0.34	GO:0014069	postsynaptic density
0.34	GO:0030425	dendrite
0.34	GO:0044297	cell body
0.30	GO:0016021	integral component of membrane

sp|P59773|K102L_HUMAN
UPF0258 protein KIAA1024-like
Search

0.39	GO:0007229	integrin-mediated signaling pathway
0.35	GO:0006508	proteolysis

0.37	GO:0004222	metalloendopeptidase activity
0.34	GO:0046872	metal ion binding
0.34	GO:0016757	transferase activity, transferring glycosyl groups

0.36	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.37

GO:0004222

sp|P59780|AP3S2_HUMAN
AP-3 complex subunit sigma-2
Search

AP3S2

0.53	AP complex subunit sigma

0.69	GO:0006886	intracellular protein transport
0.69	GO:0016192	vesicle-mediated transport
0.50	GO:0008089	anterograde axonal transport
0.49	GO:0047496	vesicle transport along microtubule
0.49	GO:0097480	establishment of synaptic vesicle localization
0.44	GO:0051126	negative regulation of actin nucleation
0.41	GO:0048072	compound eye pigmentation
0.41	GO:0033060	ocellus pigmentation
0.41	GO:0006726	eye pigment biosynthetic process
0.38	GO:0044550	secondary metabolite biosynthetic process

0.46	GO:0008565	protein transporter activity
0.33	GO:0003779	actin binding
0.33	GO:0003774	motor activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.75	GO:0030117	membrane coat
0.50	GO:1904115	axon cytoplasm
0.40	GO:0043231	intracellular membrane-bounded organelle
0.38	GO:0030659	cytoplasmic vesicle membrane
0.37	GO:0012505	endomembrane system
0.34	GO:0016459	myosin complex
0.33	GO:0031984	organelle subcompartment
0.33	GO:0030027	lamellipodium

sp|P59796|GPX6_HUMAN
Glutathione peroxidase 6
Search

0.47	Epididymal secretory glutathione peroxidase

0.71	GO:0006979	response to oxidative stress
0.69	GO:0098869	cellular oxidant detoxification
0.53	GO:0055114	oxidation-reduction process
0.50	GO:0051289	protein homotetramerization
0.44	GO:0042744	hydrogen peroxide catabolic process
0.43	GO:0033554	cellular response to stress
0.35	GO:0010269	response to selenium ion
0.35	GO:0051412	response to corticosterone
0.35	GO:0002238	response to molecule of fungal origin
0.34	GO:0006749	glutathione metabolic process

0.79	GO:0004602	glutathione peroxidase activity
0.50	GO:0008430	selenium binding
0.34	GO:0008134	transcription factor binding

0.54	GO:0097524	sperm plasma membrane
0.53	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.30	GO:0016021	integral component of membrane

0.79

EC:1.11.1.9

GO:0004602

sp|P59797|SELV_HUMAN
Selenoprotein V
Search

SELENOV

0.97	Selenoprotein V

0.42	GO:0007219	Notch signaling pathway
0.41	GO:0016998	cell wall macromolecule catabolic process
0.40	GO:0009057	macromolecule catabolic process
0.40	GO:0007275	multicellular organism development
0.39	GO:0010269	response to selenium ion
0.39	GO:1901136	carbohydrate derivative catabolic process
0.39	GO:0005975	carbohydrate metabolic process
0.39	GO:0000270	peptidoglycan metabolic process
0.38	GO:0098869	cellular oxidant detoxification
0.38	GO:1901565	organonitrogen compound catabolic process

0.49	GO:0005509	calcium ion binding
0.45	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.44	GO:0005515	protein binding
0.41	GO:0030246	carbohydrate binding
0.40	GO:0061783	peptidoglycan muralytic activity
0.39	GO:0016158	3-phytase activity
0.38	GO:0016209	antioxidant activity
0.38	GO:0005044	scavenger receptor activity
0.38	GO:0001871	pattern binding
0.37	GO:0008061	chitin binding

0.42	GO:0005576	extracellular region
0.42	GO:0019867	outer membrane
0.38	GO:0034709	methylosome
0.38	GO:0034715	pICln-Sm protein complex
0.35	GO:0005829	cytosol
0.35	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.45

GO:0004553

sp|P59817|Z280A_HUMAN
Zinc finger protein 280A
Search

0.88	Suppressor of hairy wing homolog 2

0.35	GO:0097659	nucleic acid-templated transcription
0.35	GO:1903506	regulation of nucleic acid-templated transcription
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression
0.35	GO:0010467	gene expression
0.34	GO:0034645	cellular macromolecule biosynthetic process

0.51	GO:0003676	nucleic acid binding
0.35	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.36	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|P59826|BPIB3_HUMAN
BPI fold-containing family B member 3
Search

BPIFB3

0.89	LOW QUALITY PROTEIN: BPI fold-containing family B member 3

0.73

GO:0045087

innate immune response

0.72	GO:0008289	lipid binding
0.38	GO:0005549	odorant binding

0.44	GO:0005737	cytoplasm
0.41	GO:0005576	extracellular region

sp|P59827|BPIB4_HUMAN
BPI fold-containing family B member 4
Search

BPIFB4

0.97	BPI fold-containing family B member 4

0.40

GO:0045087

innate immune response

0.72	GO:0008289	lipid binding
0.34	GO:0005549	odorant binding

0.41	GO:0005576	extracellular region
0.37	GO:0005737	cytoplasm

sp|P59861|DB131_HUMAN
Beta-defensin 131
Search

0.57	Beta-defensin

0.79	GO:0045087	innate immune response
0.78	GO:0042742	defense response to bacterium
0.48	GO:0002741	positive regulation of cytokine secretion involved in immune response
0.48	GO:0071223	cellular response to lipoteichoic acid
0.47	GO:0090026	positive regulation of monocyte chemotaxis
0.47	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.46	GO:0032722	positive regulation of chemokine production

0.66	GO:0005576	extracellular region
0.61	GO:0009986	cell surface

sp|P59894|DCDC1_HUMAN
Doublecortin domain-containing protein 1
Search

DCDC1

0.91	Doublecortin domain-containing protein 1

0.63

GO:0035556

intracellular signal transduction

0.45

GO:0005622

intracellular

sp|P59901|LIRA4_HUMAN
Leukocyte immunoglobulin-like receptor subfamily A member 4
Search

0.80	Leukocyte immunoglobulin like receptor A4

0.88	GO:0034156	negative regulation of toll-like receptor 7 signaling pathway
0.87	GO:0034164	negative regulation of toll-like receptor 9 signaling pathway
0.86	GO:0032687	negative regulation of interferon-alpha production
0.85	GO:0038095	Fc-epsilon receptor signaling pathway
0.84	GO:0032720	negative regulation of tumor necrosis factor production
0.30	GO:0006950	response to stress
0.30	GO:0006955	immune response

0.83	GO:0015026	coreceptor activity
0.70	GO:0005102	receptor binding

0.86	GO:0032997	Fc receptor complex
0.65	GO:0005887	integral component of plasma membrane

sp|P59910|DJB13_HUMAN
DnaJ homolog subfamily B member 13
Search

DNAJB13

0.82	DnaJ like protein subfamily B member 13

0.69	GO:0006457	protein folding
0.52	GO:1904158	axonemal central apparatus assembly

0.71

GO:0051082

unfolded protein binding

0.52	GO:0097224	sperm connecting piece
0.48	GO:0005930	axoneme
0.30	GO:0031224	intrinsic component of membrane

sp|P59922|OR2B8_HUMAN
Putative olfactory receptor 2B8
Search

0.45	Olfactory receptor

0.75	GO:0050911	detection of chemical stimulus involved in sensory perception of smell
0.70	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0004984	olfactory receptor activity
0.71	GO:0004930	G-protein coupled receptor activity

0.55	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P59923|ZN445_HUMAN
Zinc finger protein 445
Search

ZNF445

0.67	zinc finger protein 445

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.50	GO:0006351	transcription, DNA-templated
0.34	GO:1902679	negative regulation of RNA biosynthetic process
0.34	GO:0007219	Notch signaling pathway

0.58	GO:0003700	DNA binding transcription factor activity
0.50	GO:0003676	nucleic acid binding
0.49	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding
0.34	GO:0003682	chromatin binding

0.58	GO:0005634	nucleus
0.37	GO:0070062	extracellular exosome
0.36	GO:0005856	cytoskeleton
0.35	GO:0031974	membrane-enclosed lumen
0.35	GO:0005829	cytosol
0.34	GO:0044446	intracellular organelle part
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P59942|MCCD1_HUMAN
Mitochondrial coiled-coil domain protein 1
Search

MCCD1

0.97	Mitochondrial coiled-coil domain protein 1

0.61

GO:0005739

mitochondrion

sp|P59990|KR121_HUMAN
Keratin-associated protein 12-1
Search

0.97	Keratin-associated protein 12-1

0.44	GO:0031424	keratinization
0.34	GO:0038007	netrin-activated signaling pathway

0.36	GO:0005515	protein binding
0.34	GO:0005042	netrin receptor activity

0.83	GO:0045095	keratin filament
0.39	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|P59991|KR122_HUMAN
Keratin-associated protein 12-2
Search

0.97	Keratin-associated protein 12-2

0.43

GO:0031424

keratinization

0.37

GO:0005515

protein binding

0.83	GO:0045095	keratin filament
0.39	GO:0005829	cytosol

sp|P59998|ARPC4_HUMAN
Actin-related protein 2/3 complex subunit 4
Search

ARPC4

0.72	Actin-related protein 2/3 complex subunit 4

0.81	GO:0030041	actin filament polymerization
0.78	GO:0034314	Arp2/3 complex-mediated actin nucleation
0.35	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.35	GO:0048013	ephrin receptor signaling pathway
0.33	GO:0061024	membrane organization

0.67	GO:0003779	actin binding
0.50	GO:0030674	protein binding, bridging
0.49	GO:0005200	structural constituent of cytoskeleton
0.48	GO:0032403	protein complex binding
0.47	GO:0019899	enzyme binding

0.78	GO:0005885	Arp2/3 protein complex
0.46	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.36	GO:0042995	cell projection

sp|P60002|ELOF1_HUMAN
Transcription elongation factor 1 homolog
Search

ELOF1

0.70	Transcription elongation factor 1 homolog

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:0006414	translational elongation
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.46	GO:0006338	chromatin remodeling
0.44	GO:0051254	positive regulation of RNA metabolic process
0.44	GO:0010557	positive regulation of macromolecule biosynthetic process
0.44	GO:0031328	positive regulation of cellular biosynthetic process
0.33	GO:0007166	cell surface receptor signaling pathway

0.57	GO:0003746	translation elongation factor activity
0.54	GO:0046872	metal ion binding
0.48	GO:0000993	RNA polymerase II core binding
0.34	GO:0004930	G-protein coupled receptor activity
0.32	GO:0004386	helicase activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005634	nucleus
0.42	GO:0031974	membrane-enclosed lumen
0.40	GO:0043234	protein complex
0.39	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|P60006|APC15_HUMAN
Anaphase-promoting complex subunit 15
Search

ANAPC15

0.97	Anaphase promoting complex subunit 15

0.85	GO:1903504	regulation of mitotic spindle checkpoint
0.42	GO:0051301	cell division
0.42	GO:0007049	cell cycle
0.39	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.38	GO:1904667	negative regulation of ubiquitin protein ligase activity
0.37	GO:0031145	anaphase-promoting complex-dependent catabolic process
0.37	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process

0.80	GO:0005680	anaphase-promoting complex
0.36	GO:0005654	nucleoplasm
0.35	GO:0005829	cytosol
0.33	GO:0034708	methyltransferase complex

sp|P60008|HILS1_HUMAN
Spermatid-specific linker histone H1-like protein
Search

0.92	Histone linker H1 domain, spermatid-specific 1-like protein

0.79	GO:0006334	nucleosome assembly
0.67	GO:0007283	spermatogenesis
0.65	GO:0006342	chromatin silencing
0.65	GO:0030261	chromosome condensation
0.65	GO:0007281	germ cell development
0.63	GO:0016569	covalent chromatin modification
0.60	GO:0007275	multicellular organism development
0.59	GO:0006338	chromatin remodeling
0.51	GO:0006351	transcription, DNA-templated

0.65	GO:0042393	histone binding
0.55	GO:0003677	DNA binding

0.75	GO:0000786	nucleosome
0.71	GO:0001673	male germ cell nucleus

sp|P60014|KR10A_HUMAN
Keratin-associated protein 10-10
Search

0.96	Keratin associated protein 10-4

0.44

GO:0031424

keratinization

0.40

GO:0042802

identical protein binding

0.83	GO:0045095	keratin filament
0.40	GO:0005829	cytosol

sp|P60022|DEFB1_HUMAN
Beta-defensin 1
Search

DEFB1

0.97	Beta-defensin 1

0.86	GO:0060474	positive regulation of flagellated sperm motility involved in capacitation
0.85	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.81	GO:0050830	defense response to Gram-positive bacterium
0.80	GO:0019933	cAMP-mediated signaling
0.80	GO:0050829	defense response to Gram-negative bacterium
0.70	GO:0002227	innate immune response in mucosa
0.68	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.67	GO:0019731	antibacterial humoral response
0.39	GO:0006935	chemotaxis
0.39	GO:0007186	G-protein coupled receptor signaling pathway

0.86	GO:0031731	CCR6 chemokine receptor binding
0.71	GO:0042802	identical protein binding

0.86	GO:1990742	microvesicle
0.85	GO:0097225	sperm midpiece
0.72	GO:0019898	extrinsic component of membrane
0.58	GO:0005615	extracellular space
0.44	GO:0005622	intracellular
0.38	GO:0012505	endomembrane system
0.38	GO:0031974	membrane-enclosed lumen

sp|P60033|CD81_HUMAN
CD81 antigen
Search

CD81

0.60	Tetraspanin

0.58	GO:0043126	regulation of 1-phosphatidylinositol 4-kinase activity
0.56	GO:1904352	positive regulation of protein catabolic process in the vacuole
0.55	GO:0090218	positive regulation of lipid kinase activity
0.54	GO:0071404	cellular response to low-density lipoprotein particle stimulus
0.54	GO:1903727	positive regulation of phospholipid metabolic process
0.53	GO:0061462	protein localization to lysosome
0.53	GO:0030890	positive regulation of B cell proliferation
0.53	GO:0000187	activation of MAPK activity
0.53	GO:0031623	receptor internalization
0.53	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation

0.55	GO:1990459	transferrin receptor binding
0.54	GO:0104005	hijacked molecular function

0.53	GO:0001772	immunological synapse
0.51	GO:0016323	basolateral plasma membrane
0.51	GO:0070062	extracellular exosome
0.47	GO:0005887	integral component of plasma membrane

sp|P60059|SC61G_HUMAN
Protein transport protein Sec61 subunit gamma
Search

SEC61G

0.96	Transport protein Sec61 subunit gamma

0.71	GO:0006605	protein targeting
0.70	GO:0071806	protein transmembrane transport
0.41	GO:0072599	establishment of protein localization to endoplasmic reticulum
0.39	GO:0001555	oocyte growth
0.38	GO:0030728	ovulation
0.35	GO:0036498	IRE1-mediated unfolded protein response
0.34	GO:0016310	phosphorylation
0.34	GO:0022406	membrane docking
0.33	GO:0007275	multicellular organism development

0.75	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
0.35	GO:0016301	kinase activity
0.34	GO:0005543	phospholipid binding
0.33	GO:0005515	protein binding

0.45	GO:0005622	intracellular
0.40	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.37	GO:0044422	organelle part
0.36	GO:0043227	membrane-bounded organelle
0.30	GO:0031224	intrinsic component of membrane

sp|P60153|RNAS9_HUMAN
Inactive ribonuclease-like protein 9
Search

RNASE9

0.97	Ribonuclease A family member 9 (inactive)

0.43

GO:0090501

RNA phosphodiester bond hydrolysis

0.51	GO:0003676	nucleic acid binding
0.45	GO:0004540	ribonuclease activity
0.43	GO:0004519	endonuclease activity

0.53

GO:0005576

extracellular region

sp|P60174|TPIS_HUMAN
Triosephosphate isomerase
Search

TPI1

0.47	Triosephosphate isomerase

0.73	GO:0019319	hexose biosynthetic process
0.72	GO:0006098	pentose-phosphate shunt
0.71	GO:0006006	glucose metabolic process
0.70	GO:0006757	ATP generation from ADP
0.69	GO:0006090	pyruvate metabolic process
0.68	GO:0016052	carbohydrate catabolic process
0.50	GO:0046166	glyceraldehyde-3-phosphate biosynthetic process
0.45	GO:0046174	polyol catabolic process
0.45	GO:0006071	glycerol metabolic process
0.45	GO:0007275	multicellular organism development

0.78	GO:0004807	triose-phosphate isomerase activity
0.49	GO:0031625	ubiquitin protein ligase binding

0.43	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.34	GO:0005634	nucleus

0.78	EC:5.3.1.1	GO:0004807
0.78	KEGG:R01015	GO:0004807

sp|P60201|MYPR_HUMAN
Myelin proteolipid protein
Search

PLP1

0.93	Myelin proteolipid protein B

0.62	GO:0022010	central nervous system myelination
0.61	GO:0014002	astrocyte development
0.60	GO:0042759	long-chain fatty acid biosynthetic process
0.58	GO:0048469	cell maturation
0.57	GO:0006954	inflammatory response
0.56	GO:0061564	axon development
0.52	GO:0010628	positive regulation of gene expression
0.41	GO:0007229	integrin-mediated signaling pathway
0.39	GO:0021762	substantia nigra development
0.35	GO:0007268	chemical synaptic transmission

0.43	GO:0019911	structural constituent of myelin sheath
0.38	GO:0042802	identical protein binding

0.59	GO:0043209	myelin sheath
0.45	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P60228|EIF3E_HUMAN
Eukaryotic translation initiation factor 3 subunit E
Search

EIF3E

0.69	Eukaryotic translation initiation factor 3 subunit E-B

0.72	GO:0001731	formation of translation preinitiation complex
0.71	GO:0006446	regulation of translational initiation
0.54	GO:1902416	positive regulation of mRNA binding
0.52	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.49	GO:0045727	positive regulation of translation
0.34	GO:0017148	negative regulation of translation

0.73	GO:0003743	translation initiation factor activity
0.52	GO:0047485	protein N-terminus binding
0.50	GO:0045296	cadherin binding

0.78	GO:0005852	eukaryotic translation initiation factor 3 complex
0.71	GO:0016282	eukaryotic 43S preinitiation complex
0.71	GO:0033290	eukaryotic 48S preinitiation complex
0.58	GO:0005634	nucleus
0.45	GO:0005829	cytosol
0.45	GO:0031974	membrane-enclosed lumen
0.41	GO:0044446	intracellular organelle part
0.34	GO:0070062	extracellular exosome
0.33	GO:0005694	chromosome
0.30	GO:0016020	membrane

sp|P60321|NANO2_HUMAN
Nanos homolog 2
Search

NANOS2

0.96	Nanos like protein 2

0.72	GO:0006417	regulation of translation
0.68	GO:1900153	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
0.61	GO:0007283	spermatogenesis
0.60	GO:0034249	negative regulation of cellular amide metabolic process
0.60	GO:0030718	germ-line stem cell population maintenance
0.58	GO:0045835	negative regulation of meiotic nuclear division
0.57	GO:0032269	negative regulation of cellular protein metabolic process
0.56	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
0.54	GO:0010629	negative regulation of gene expression
0.51	GO:0006401	RNA catabolic process

0.63	GO:0008270	zinc ion binding
0.59	GO:0003723	RNA binding
0.37	GO:0005515	protein binding

0.62	GO:0048471	perinuclear region of cytoplasm
0.62	GO:0000932	P-body
0.50	GO:0005634	nucleus
0.48	GO:0010494	cytoplasmic stress granule
0.38	GO:0043186	P granule

sp|P60323|NANO3_HUMAN
Nanos homolog 3
Search

NANOS3

0.97	Nanos like protein 3

0.72	GO:0006417	regulation of translation
0.65	GO:1900153	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
0.60	GO:0007276	gamete generation
0.58	GO:0034249	negative regulation of cellular amide metabolic process
0.56	GO:0022412	cellular process involved in reproduction in multicellular organism
0.56	GO:2001234	negative regulation of apoptotic signaling pathway
0.55	GO:0032269	negative regulation of cellular protein metabolic process
0.55	GO:0051726	regulation of cell cycle
0.55	GO:0003006	developmental process involved in reproduction
0.55	GO:2000113	negative regulation of cellular macromolecule biosynthetic process

0.63	GO:0008270	zinc ion binding
0.59	GO:0003723	RNA binding
0.37	GO:0005515	protein binding
0.33	GO:0016301	kinase activity

0.60	GO:0000932	P-body
0.60	GO:0048471	perinuclear region of cytoplasm
0.55	GO:0010494	cytoplasmic stress granule
0.49	GO:0005634	nucleus
0.41	GO:0043186	P granule

sp|P60328|KR123_HUMAN
Keratin-associated protein 12-3
Search

0.97	Keratin-associated protein 12-3

0.43

GO:0031424

keratinization

0.35	GO:0005515	protein binding
0.33	GO:0030246	carbohydrate binding

0.82	GO:0045095	keratin filament
0.38	GO:0005829	cytosol

sp|P60329|KR124_HUMAN
Keratin-associated protein 12-4
Search

0.95	Keratin-associated protein 12-4

0.45

GO:0031424

keratinization

0.39

GO:0005515

protein binding

0.83	GO:0045095	keratin filament
0.40	GO:0005829	cytosol

sp|P60331|KR101_HUMAN
Keratin-associated protein 10-1
Search

0.96	Keratin associated protein 10-9

0.45

GO:0031424

keratinization

0.38

GO:0042802

identical protein binding

0.83	GO:0045095	keratin filament
0.40	GO:0005829	cytosol

sp|P60368|KR102_HUMAN
Keratin-associated protein 10-2
Search

0.96	Keratin-associated protein 10-9

0.46

GO:0031424

keratinization

0.41

GO:0042802

identical protein binding

0.83	GO:0045095	keratin filament
0.40	GO:0005829	cytosol

sp|P60369|KR103_HUMAN
Keratin-associated protein 10-3
Search

0.95	Keratin-associated protein 10-4

0.44

GO:0031424

keratinization

0.41

GO:0042802

identical protein binding

0.83	GO:0045095	keratin filament
0.39	GO:0005829	cytosol

sp|P60370|KR105_HUMAN
Keratin-associated protein 10-5
Search

0.96	Keratin associated protein 10-2

0.45

GO:0031424

keratinization

0.39

GO:0042802

identical protein binding

0.83	GO:0045095	keratin filament
0.40	GO:0005829	cytosol

sp|P60371|KR106_HUMAN
Keratin-associated protein 10-6
Search

0.97	Keratin-associated protein 10-4

0.46

GO:0031424

keratinization

0.40

GO:0042802

identical protein binding

0.83	GO:0045095	keratin filament
0.41	GO:0005829	cytosol

sp|P60372|KR104_HUMAN
Keratin-associated protein 10-4
Search

0.95	Keratin associated protein 10-4

0.45

GO:0031424

keratinization

0.40

GO:0042802

identical protein binding

0.83	GO:0045095	keratin filament
0.40	GO:0005829	cytosol

sp|P60409|KR107_HUMAN
Keratin-associated protein 10-7
Search

0.97	Keratin-associated protein 10-4

0.45

GO:0031424

keratinization

0.40

GO:0042802

identical protein binding

0.83	GO:0045095	keratin filament
0.40	GO:0005829	cytosol

sp|P60410|KR108_HUMAN
Keratin-associated protein 10-8
Search

0.91	Keratin-associated protein 10-4

0.44

GO:0031424

keratinization

0.40

GO:0042802

identical protein binding

0.83	GO:0045095	keratin filament
0.39	GO:0005829	cytosol

sp|P60411|KR109_HUMAN
Keratin-associated protein 10-9
Search

0.96	Keratin-associated protein 10-9

0.46

GO:0031424

keratinization

0.41

GO:0042802

identical protein binding

0.83	GO:0045095	keratin filament
0.41	GO:0005829	cytosol

sp|P60412|KR10B_HUMAN
Keratin-associated protein 10-11
Search

0.96	Keratin associated protein 10-4

0.44

GO:0031424

keratinization

0.41

GO:0042802

identical protein binding

0.83	GO:0045095	keratin filament
0.39	GO:0005829	cytosol

sp|P60413|KR10C_HUMAN
Keratin-associated protein 10-12
Search

0.95	Keratin-associated protein 10-4

0.44

GO:0031424

keratinization

0.38

GO:0042802

identical protein binding

0.83	GO:0045095	keratin filament
0.39	GO:0005829	cytosol

sp|P60468|SC61B_HUMAN
Protein transport protein Sec61 subunit beta
Search

SEC61B

0.75	Transport protein Sec61 subunit beta (Fragment)

0.69	GO:0006886	intracellular protein transport
0.54	GO:1903513	endoplasmic reticulum to cytosol transport
0.52	GO:0030433	ubiquitin-dependent ERAD pathway
0.51	GO:0006606	protein import into nucleus
0.46	GO:0072599	establishment of protein localization to endoplasmic reticulum
0.45	GO:0090150	establishment of protein localization to membrane
0.44	GO:0071806	protein transmembrane transport
0.43	GO:0065009	regulation of molecular function
0.35	GO:0036498	IRE1-mediated unfolded protein response
0.34	GO:0051103	DNA ligation involved in DNA repair

0.57	GO:0048408	epidermal growth factor binding
0.48	GO:0005086	ARF guanyl-nucleotide exchange factor activity
0.46	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
0.35	GO:0043022	ribosome binding
0.34	GO:0004675	transmembrane receptor protein serine/threonine kinase activity
0.34	GO:0003723	RNA binding
0.34	GO:0003910	DNA ligase (ATP) activity
0.34	GO:0004702	signal transducer, downstream of receptor, with serine/threonine kinase activity
0.33	GO:0008641	ubiquitin-like modifier activating enzyme activity
0.33	GO:0032559	adenyl ribonucleotide binding

0.85	GO:0005784	Sec61 translocon complex
0.51	GO:0031205	endoplasmic reticulum Sec complex
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0004675

sp|P60484|PTEN_HUMAN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
Search

PTEN

0.83	Phosphatase and tensin homolog A

0.86	GO:0051895	negative regulation of focal adhesion assembly
0.85	GO:0051898	negative regulation of protein kinase B signaling
0.83	GO:0030336	negative regulation of cell migration
0.81	GO:0046856	phosphatidylinositol dephosphorylation
0.80	GO:0046855	inositol phosphate dephosphorylation
0.79	GO:0008285	negative regulation of cell proliferation
0.79	GO:0031647	regulation of protein stability
0.78	GO:2000808	negative regulation of synaptic vesicle clustering
0.77	GO:1903984	positive regulation of TRAIL-activated apoptotic signaling pathway
0.76	GO:1903689	regulation of wound healing, spreading of epidermal cells

0.87	GO:0051800	phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity
0.87	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity
0.85	GO:0030165	PDZ domain binding
0.79	GO:0051717	inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity
0.78	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.75	GO:0004725	protein tyrosine phosphatase activity
0.74	GO:1990381	ubiquitin-specific protease binding
0.73	GO:0004438	phosphatidylinositol-3-phosphatase activity
0.70	GO:0010997	anaphase-promoting complex binding
0.65	GO:0019901	protein kinase binding

0.75	GO:0035749	myelin sheath adaxonal region
0.74	GO:0043220	Schmidt-Lanterman incisure
0.68	GO:0016324	apical plasma membrane
0.65	GO:0043005	neuron projection
0.64	GO:0009898	cytoplasmic side of plasma membrane
0.60	GO:0005654	nucleoplasm
0.59	GO:0005829	cytosol
0.38	GO:0036477	somatodendritic compartment
0.38	GO:0045211	postsynaptic membrane
0.38	GO:0120038	plasma membrane bounded cell projection part

0.87

EC:3.1.3.67

GO:0016314

sp|P60507|EFC1_HUMAN
Endogenous retrovirus group FC1 Env polyprotein
Search

0.96	ERV-BabFcenv provirus ancestral Env polyprotein

0.60	GO:0045026	plasma membrane fusion
0.53	GO:0006949	syncytium formation
0.38	GO:0060711	labyrinthine layer development

0.61	GO:0036338	viral membrane
0.49	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|P60508|SYCY2_HUMAN
Syncytin-2
Search

ERVFRD-1

0.58	Endogenous retrovirus group FRD member 1, envelope

0.61	GO:0006949	syncytium formation
0.60	GO:0045026	plasma membrane fusion
0.38	GO:0019064	fusion of virus membrane with host plasma membrane
0.38	GO:0019062	virion attachment to host cell
0.34	GO:0044826	viral genome integration into host DNA
0.34	GO:0075713	establishment of integrated proviral latency
0.34	GO:0015074	DNA integration
0.33	GO:0019068	virion assembly
0.33	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.33	GO:0006278	RNA-dependent DNA biosynthetic process

0.34	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.33	GO:0003964	RNA-directed DNA polymerase activity
0.33	GO:0070001	aspartic-type peptidase activity
0.33	GO:0008270	zinc ion binding
0.33	GO:0004175	endopeptidase activity
0.33	GO:0005198	structural molecule activity
0.32	GO:0003677	DNA binding

0.58	GO:0036338	viral membrane
0.41	GO:0005886	plasma membrane
0.37	GO:0020002	host cell plasma membrane
0.37	GO:0055036	virion membrane
0.33	GO:0019028	viral capsid
0.30	GO:0016021	integral component of membrane

0.34

GO:0004523

sp|P60509|ERB1_HUMAN
Endogenous retrovirus group PABLB member 1 Env polyprotein
Search

0.97	Endogenous retrovirus group PABLB member 1 Env polyprotein

0.43	GO:0045026	plasma membrane fusion
0.33	GO:0010951	negative regulation of endopeptidase activity

0.34

GO:0004869

cysteine-type endopeptidase inhibitor activity

0.65	GO:0036338	viral membrane
0.36	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|P60510|PP4C_HUMAN
Serine/threonine-protein phosphatase 4 catalytic subunit
Search

PPP4C

0.48	Serine/threonine-protein phosphatase 4 catalytic subunit B

0.70	GO:0006470	protein dephosphorylation
0.55	GO:0010569	regulation of double-strand break repair via homologous recombination
0.38	GO:0048264	determination of ventral identity
0.36	GO:0038061	NIK/NF-kappaB signaling
0.36	GO:0030513	positive regulation of BMP signaling pathway
0.35	GO:0021952	central nervous system projection neuron axonogenesis
0.35	GO:0071347	cellular response to interleukin-1
0.34	GO:0001525	angiogenesis
0.34	GO:0007420	brain development
0.33	GO:0016310	phosphorylation

0.71	GO:0004721	phosphoprotein phosphatase activity
0.37	GO:0004704	NF-kappaB-inducing kinase activity
0.36	GO:0046872	metal ion binding
0.35	GO:0005515	protein binding
0.34	GO:0044877	macromolecular complex binding
0.33	GO:0004332	fructose-bisphosphate aldolase activity

0.53	GO:0030289	protein phosphatase 4 complex
0.46	GO:0005829	cytosol
0.44	GO:0005634	nucleus
0.41	GO:0005886	plasma membrane
0.41	GO:0005815	microtubule organizing center
0.33	GO:0031974	membrane-enclosed lumen
0.30	GO:0031224	intrinsic component of membrane

0.71

GO:0004721

sp|P60520|GBRL2_HUMAN
Gamma-aminobutyric acid receptor-associated protein-like 2
Search

GABARAPL2

0.97	Gamma-aminobutyric acid receptor-associated protein 2

0.77	GO:0006914	autophagy
0.53	GO:1901799	negative regulation of proteasomal protein catabolic process
0.49	GO:0006995	cellular response to nitrogen starvation
0.49	GO:0061726	mitochondrion disassembly
0.48	GO:0007033	vacuole organization
0.45	GO:0070925	organelle assembly
0.37	GO:0048193	Golgi vesicle transport
0.37	GO:0015031	protein transport
0.36	GO:0032781	positive regulation of ATPase activity
0.35	GO:0032258	protein localization by the Cvt pathway

0.51	GO:0031625	ubiquitin protein ligase binding
0.38	GO:0030957	Tat protein binding
0.36	GO:0051117	ATPase binding
0.36	GO:0000149	SNARE binding
0.35	GO:0008429	phosphatidylethanolamine binding
0.35	GO:0031386	protein tag
0.35	GO:0050811	GABA receptor binding
0.34	GO:0048487	beta-tubulin binding
0.34	GO:0008017	microtubule binding
0.33	GO:0004252	serine-type endopeptidase activity

0.57	GO:0000421	autophagosome membrane
0.49	GO:0000139	Golgi membrane
0.44	GO:0005829	cytosol
0.37	GO:0031410	cytoplasmic vesicle
0.36	GO:0120095	vacuole-isolation membrane contact site
0.35	GO:0000407	phagophore assembly site
0.35	GO:0000329	fungal-type vacuole membrane
0.34	GO:0019898	extrinsic component of membrane
0.34	GO:0005739	mitochondrion

0.33

GO:0004252

sp|P60568|IL2_HUMAN
Interleukin-2
Search

IL2

0.96	Interleukin-2

0.83	GO:0002250	adaptive immune response
0.76	GO:0010469	regulation of receptor activity
0.61	GO:0046013	regulation of T cell homeostatic proliferation
0.61	GO:0002903	negative regulation of B cell apoptotic process
0.60	GO:0042104	positive regulation of activated T cell proliferation
0.60	GO:0032740	positive regulation of interleukin-17 production
0.60	GO:0051024	positive regulation of immunoglobulin secretion
0.60	GO:2000320	negative regulation of T-helper 17 cell differentiation
0.60	GO:0048304	positive regulation of isotype switching to IgG isotypes
0.59	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein

0.87	GO:0005134	interleukin-2 receptor binding
0.80	GO:0005125	cytokine activity
0.78	GO:0008083	growth factor activity
0.41	GO:0031851	kappa-type opioid receptor binding
0.40	GO:0043208	glycosphingolipid binding
0.37	GO:0019209	kinase activator activity
0.37	GO:0030246	carbohydrate binding
0.35	GO:0005088	Ras guanyl-nucleotide exchange factor activity

0.73	GO:0005615	extracellular space
0.32	GO:0005622	intracellular

sp|P60602|ROMO1_HUMAN
Reactive oxygen species modulator 1
Search

ROMO1

0.97	Reactive oxygen species modulator 1

0.55	GO:2000379	positive regulation of reactive oxygen species metabolic process
0.54	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.54	GO:0001302	replicative cell aging
0.53	GO:0050830	defense response to Gram-positive bacterium
0.52	GO:0050829	defense response to Gram-negative bacterium
0.52	GO:0051715	cytolysis in other organism
0.52	GO:0008284	positive regulation of cell proliferation
0.50	GO:0034614	cellular response to reactive oxygen species
0.42	GO:1903146	regulation of autophagy of mitochondrion

0.44	GO:0005739	mitochondrion
0.37	GO:0019866	organelle inner membrane
0.30	GO:0016021	integral component of membrane

sp|P60604|UB2G2_HUMAN
Ubiquitin-conjugating enzyme E2 G2
Search

UBE2G2

0.94	Ubiquitin-conjugating enzyme E2G 2

0.56	GO:1904153	negative regulation of retrograde protein transport, ER to cytosol
0.55	GO:0035458	cellular response to interferon-beta
0.55	GO:0070936	protein K48-linked ubiquitination
0.54	GO:0018279	protein N-linked glycosylation via asparagine
0.53	GO:0030433	ubiquitin-dependent ERAD pathway
0.36	GO:0016925	protein sumoylation
0.33	GO:0006468	protein phosphorylation

0.55	GO:0061631	ubiquitin conjugating enzyme activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0042802	identical protein binding
0.45	GO:0031625	ubiquitin protein ligase binding
0.44	GO:0061630	ubiquitin protein ligase activity
0.35	GO:0016874	ligase activity
0.33	GO:0004672	protein kinase activity

0.45	GO:0005783	endoplasmic reticulum
0.44	GO:0005829	cytosol

0.35

GO:0016874

sp|P60606|CTXN1_HUMAN
Cortexin-1
Search

CTXN1

0.97	Cortexin 1

0.36

GO:0007417

central nervous system development

0.30

GO:0044425

membrane part

sp|P60608|EFC2_HUMAN
Endogenous retrovirus group FC1 member 1 Env polyprotein
Search

0.92	ERV-BabFcenv provirus ancestral Env polyprotein

0.67	GO:0045026	plasma membrane fusion
0.49	GO:0060711	labyrinthine layer development
0.49	GO:0000768	syncytium formation by plasma membrane fusion
0.44	GO:0060674	placenta blood vessel development

0.61	GO:0036338	viral membrane
0.46	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|P60660|MYL6_HUMAN
Myosin light polypeptide 6
Search

MYL6

0.93	Smooth muscle myosin essential light chain

0.42	GO:0030049	muscle filament sliding
0.39	GO:0061061	muscle structure development
0.39	GO:0014706	striated muscle tissue development
0.38	GO:0048513	animal organ development
0.34	GO:0031032	actomyosin structure organization
0.34	GO:0010927	cellular component assembly involved in morphogenesis
0.34	GO:0048468	cell development
0.34	GO:0097435	supramolecular fiber organization
0.33	GO:0070925	organelle assembly
0.33	GO:0051301	cell division

0.70	GO:0005509	calcium ion binding
0.50	GO:0008307	structural constituent of muscle
0.42	GO:0030898	actin-dependent ATPase activity
0.38	GO:0003774	motor activity
0.35	GO:0005515	protein binding
0.34	GO:0043531	ADP binding
0.33	GO:0044877	macromolecular complex binding
0.33	GO:0000287	magnesium ion binding
0.33	GO:0003735	structural constituent of ribosome

0.51	GO:0016461	unconventional myosin complex
0.48	GO:0005903	brush border
0.39	GO:0070062	extracellular exosome
0.38	GO:0031012	extracellular matrix
0.37	GO:0005829	cytosol
0.36	GO:0005859	muscle myosin complex
0.35	GO:0097513	myosin II filament
0.34	GO:0042641	actomyosin
0.33	GO:0005840	ribosome
0.30	GO:0016020	membrane

sp|P60673|PROF3_HUMAN
Profilin-3
Search

PFN3

0.65

Profilin

0.72	GO:0030036	actin cytoskeleton organization
0.55	GO:0032233	positive regulation of actin filament bundle assembly
0.51	GO:0030833	regulation of actin filament polymerization
0.37	GO:0006508	proteolysis

0.73	GO:0003779	actin binding
0.44	GO:0008289	lipid binding
0.39	GO:0004252	serine-type endopeptidase activity

0.43	GO:0005856	cytoskeleton
0.40	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm
0.38	GO:0005576	extracellular region

0.39

GO:0004252

sp|P60709|ACTB_HUMAN
Actin, cytoplasmic 1
Search

ACTB

0.64	Beta-actin variant 2

0.53	GO:0098974	postsynaptic actin cytoskeleton organization
0.52	GO:0072749	cellular response to cytochalasin B
0.49	GO:0032091	negative regulation of protein binding
0.46	GO:0045214	sarcomere organization
0.46	GO:0071346	cellular response to interferon-gamma
0.44	GO:0048870	cell motility
0.39	GO:0070527	platelet aggregation
0.39	GO:0001895	retina homeostasis
0.37	GO:0021762	substantia nigra development
0.37	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis

0.53	GO:0098973	structural constituent of postsynaptic actin cytoskeleton
0.51	GO:0030554	adenyl nucleotide binding
0.51	GO:0030957	Tat protein binding
0.51	GO:0050998	nitric-oxide synthase binding
0.50	GO:0097367	carbohydrate derivative binding
0.50	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0008144	drug binding
0.50	GO:0042802	identical protein binding
0.49	GO:0019894	kinesin binding
0.49	GO:0005522	profilin binding

0.75	GO:0097433	dense body
0.70	GO:0005925	focal adhesion
0.61	GO:0005856	cytoskeleton
0.53	GO:0043209	myelin sheath
0.50	GO:0005886	plasma membrane
0.47	GO:0035267	NuA4 histone acetyltransferase complex
0.47	GO:0036464	cytoplasmic ribonucleoprotein granule
0.47	GO:0070062	extracellular exosome
0.46	GO:0044448	cell cortex part
0.45	GO:0005829	cytosol

sp|P60763|RAC3_HUMAN
Ras-related C3 botulinum toxin substrate 3
Search

0.83	Ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)

0.76	GO:0007264	small GTPase mediated signal transduction
0.57	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading
0.54	GO:0021894	cerebral cortex GABAergic interneuron development
0.53	GO:0051932	synaptic transmission, GABAergic
0.53	GO:0014041	regulation of neuron maturation
0.52	GO:0048873	homeostasis of number of cells within a tissue
0.51	GO:0033630	positive regulation of cell adhesion mediated by integrin
0.51	GO:0120036	plasma membrane bounded cell projection organization
0.50	GO:0030036	actin cytoskeleton organization
0.50	GO:0050885	neuromuscular process controlling balance

0.67	GO:0003924	GTPase activity
0.65	GO:0005525	GTP binding
0.50	GO:0048306	calcium-dependent protein binding
0.48	GO:0031996	thioesterase binding
0.44	GO:0019901	protein kinase binding
0.42	GO:0051022	Rho GDP-dissociation inhibitor binding
0.38	GO:0030742	GTP-dependent protein binding
0.37	GO:0051117	ATPase binding
0.36	GO:0042826	histone deacetylase binding
0.36	GO:0017137	Rab GTPase binding

0.54	GO:0005884	actin filament
0.53	GO:0036477	somatodendritic compartment
0.52	GO:0043005	neuron projection
0.51	GO:0120038	plasma membrane bounded cell projection part
0.48	GO:0044297	cell body
0.48	GO:0030427	site of polarized growth
0.48	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0012505	endomembrane system
0.46	GO:0030027	lamellipodium
0.46	GO:0031256	leading edge membrane

0.34

GO:0004674

sp|P60827|C1QT8_HUMAN
Complement C1q tumor necrosis factor-related protein 8
Search

0.94	LOW QUALITY PROTEIN: complement C1q tumor necrosis factor-related protein 8

0.54	GO:0070208	protein heterotrimerization
0.51	GO:2000860	positive regulation of aldosterone secretion
0.49	GO:0090331	negative regulation of platelet aggregation
0.47	GO:0051897	positive regulation of protein kinase B signaling
0.46	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.46	GO:0010906	regulation of glucose metabolic process
0.45	GO:0043410	positive regulation of MAPK cascade
0.45	GO:0051260	protein homooligomerization
0.43	GO:0010628	positive regulation of gene expression
0.36	GO:0038169	somatostatin receptor signaling pathway

0.47	GO:0005518	collagen binding
0.41	GO:0042802	identical protein binding
0.37	GO:0033925	mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity
0.36	GO:0004994	somatostatin receptor activity
0.34	GO:0003924	GTPase activity
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0032561	guanyl ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.78	GO:0005581	collagen trimer
0.66	GO:0005576	extracellular region
0.42	GO:0005887	integral component of plasma membrane
0.33	GO:0005737	cytoplasm

0.37

EC:3.2.1.96

GO:0033925

sp|P60842|IF4A1_HUMAN
Eukaryotic initiation factor 4A-I
Search

EIF4A1

0.84	Eukaryotic initiation factor 4A-II

0.69	GO:0006413	translational initiation
0.49	GO:0010501	RNA secondary structure unwinding
0.48	GO:1900260	negative regulation of RNA-directed 5'-3' RNA polymerase activity
0.45	GO:1990823	response to leukemia inhibitory factor
0.43	GO:0071345	cellular response to cytokine stimulus
0.39	GO:0010468	regulation of gene expression
0.34	GO:0006401	RNA catabolic process
0.34	GO:0016071	mRNA metabolic process
0.33	GO:0016032	viral process
0.33	GO:0006508	proteolysis

0.75	GO:0004004	ATP-dependent RNA helicase activity
0.70	GO:0003743	translation initiation factor activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0003725	double-stranded RNA binding
0.35	GO:0000339	RNA cap binding
0.34	GO:0005515	protein binding
0.34	GO:0003729	mRNA binding
0.34	GO:0008234	cysteine-type peptidase activity

0.45	GO:0005730	nucleolus
0.43	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0031012	extracellular matrix
0.37	GO:0070062	extracellular exosome
0.35	GO:0016281	eukaryotic translation initiation factor 4F complex
0.34	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.34

GO:0008234

sp|P60852|ZP1_HUMAN
Zona pellucida sperm-binding protein 1
Search

ZP1

0.97	LOW QUALITY PROTEIN: zona pellucida sperm-binding protein 1

0.50	GO:0007338	single fertilization
0.49	GO:2000360	negative regulation of binding of sperm to zona pellucida
0.48	GO:2000344	positive regulation of acrosome reaction
0.47	GO:0002922	positive regulation of humoral immune response
0.46	GO:0042102	positive regulation of T cell proliferation
0.46	GO:0017156	calcium ion regulated exocytosis
0.40	GO:0009988	cell-cell recognition
0.33	GO:0006633	fatty acid biosynthetic process
0.32	GO:0055114	oxidation-reduction process

0.49	GO:0032190	acrosin binding
0.43	GO:0042802	identical protein binding
0.34	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water

0.63	GO:0005576	extracellular region
0.38	GO:0005886	plasma membrane
0.32	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.34

EC:1.14.19

GO:0016717

sp|P60866|RS20_HUMAN
40S ribosomal protein S20
Search

RPS20

0.75	Ribosomal protein S20

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.33	GO:0019083	viral transcription
0.33	GO:0016072	rRNA metabolic process
0.33	GO:0042254	ribosome biogenesis
0.33	GO:0036211	protein modification process

0.64	GO:0003735	structural constituent of ribosome
0.58	GO:0003723	RNA binding
0.34	GO:0005515	protein binding
0.33	GO:0004674	protein serine/threonine kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.70	GO:0015935	small ribosomal subunit
0.50	GO:0022626	cytosolic ribosome
0.36	GO:0031012	extracellular matrix
0.36	GO:0070062	extracellular exosome
0.35	GO:0098556	cytoplasmic side of rough endoplasmic reticulum membrane
0.33	GO:0005654	nucleoplasm

0.33

GO:0004674

sp|P60880|SNP25_HUMAN
Synaptosomal-associated protein 25
Search

SNAP25

0.78	Synaptosomal-associated protein 25-A

0.85	GO:1990926	short-term synaptic potentiation
0.84	GO:0099590	neurotransmitter receptor internalization
0.84	GO:0098881	exocytic insertion of neurotransmitter receptor to plasma membrane
0.83	GO:0031915	positive regulation of synaptic plasticity
0.83	GO:0098969	neurotransmitter receptor transport to postsynaptic membrane
0.79	GO:0060291	long-term synaptic potentiation
0.79	GO:0099643	signal release from synapse
0.79	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.78	GO:0008306	associative learning
0.78	GO:0007626	locomotory behavior

0.85	GO:0017075	syntaxin-1 binding
0.57	GO:0005484	SNAP receptor activity

0.86	GO:0070032	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex
0.80	GO:0031083	BLOC-1 complex
0.78	GO:0042734	presynaptic membrane
0.75	GO:0043209	myelin sheath
0.74	GO:0008021	synaptic vesicle
0.73	GO:0043005	neuron projection
0.73	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.73	GO:0005802	trans-Golgi network
0.72	GO:0036477	somatodendritic compartment
0.72	GO:0048471	perinuclear region of cytoplasm

sp|P60891|PRPS1_HUMAN
Ribose-phosphate pyrophosphokinase 1
Search

PRPS1

0.78	Phosphoribosyl pyrophosphate synthetase 1

0.66	GO:0009116	nucleoside metabolic process
0.66	GO:0034418	urate biosynthetic process
0.65	GO:0009156	ribonucleoside monophosphate biosynthetic process
0.64	GO:0009165	nucleotide biosynthetic process
0.59	GO:0046101	hypoxanthine biosynthetic process
0.54	GO:0007399	nervous system development
0.47	GO:0006163	purine nucleotide metabolic process
0.38	GO:0008584	male gonad development
0.36	GO:0016310	phosphorylation

0.78	GO:0004749	ribose phosphate diphosphokinase activity
0.64	GO:0000287	magnesium ion binding
0.56	GO:0042802	identical protein binding
0.51	GO:0046983	protein dimerization activity
0.44	GO:0032559	adenyl ribonucleotide binding
0.43	GO:0008144	drug binding
0.43	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0016301	kinase activity

0.78	EC:2.7.6.1	GO:0004749
0.78	KEGG:R01049	GO:0004749

sp|P60893|GPR85_HUMAN
Probable G-protein coupled receptor 85
Search

GPR85

0.73	G protein-coupled receptor 85 B

0.69

GO:0007186

G-protein coupled receptor signaling pathway

0.70	GO:0004930	G-protein coupled receptor activity
0.35	GO:0005057	signal transducer activity, downstream of receptor
0.33	GO:0005515	protein binding

0.50	GO:0005783	endoplasmic reticulum
0.43	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|P60896|SEM1_HUMAN
26S proteasome complex subunit SEM1
Search

0.93	Split hand/foot malformation

0.81	GO:0043248	proteasome assembly
0.81	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.76	GO:0051028	mRNA transport
0.75	GO:0006405	RNA export from nucleus
0.54	GO:0010467	gene expression
0.47	GO:0000724	double-strand break repair via homologous recombination
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.35	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway

0.35	GO:0005515	protein binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0097367	carbohydrate derivative binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.84	GO:0008541	proteasome regulatory particle, lid subcomplex
0.38	GO:0032039	integrator complex
0.34	GO:0005829	cytosol
0.34	GO:0031011	Ino80 complex

sp|P60900|PSA6_HUMAN
Proteasome subunit alpha type-6
Search

PSMA6

0.49	Proteasome endopeptidase complex

0.72	GO:0051603	proteolysis involved in cellular protein catabolic process
0.68	GO:0043632	modification-dependent macromolecule catabolic process
0.51	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.39	GO:0071346	cellular response to interferon-gamma
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
0.35	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.35	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation

0.77	GO:0004298	threonine-type endopeptidase activity
0.53	GO:0051059	NF-kappaB binding
0.42	GO:0003723	RNA binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.79	GO:0019773	proteasome core complex, alpha-subunit complex
0.58	GO:0005634	nucleus
0.51	GO:0005844	polysome
0.50	GO:0000932	P-body
0.45	GO:0070013	intracellular organelle lumen
0.41	GO:0044446	intracellular organelle part
0.37	GO:0030017	sarcomere
0.36	GO:0070062	extracellular exosome
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.77

EC:3.4.25

GO:0004298

sp|P60903|S10AA_HUMAN
Protein S100-A10
Search

S100A10

0.97	S100 calcium binding protein A10

0.56	GO:0051894	positive regulation of focal adhesion assembly
0.56	GO:0051290	protein heterotetramerization
0.55	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading
0.55	GO:0051496	positive regulation of stress fiber assembly
0.55	GO:0001765	membrane raft assembly
0.53	GO:0072659	protein localization to plasma membrane
0.53	GO:0006900	vesicle budding from membrane
0.51	GO:0051099	positive regulation of binding
0.50	GO:0043547	positive regulation of GTPase activity
0.46	GO:0042127	regulation of cell proliferation

0.67	GO:0005509	calcium ion binding
0.54	GO:0044325	ion channel binding
0.51	GO:0042803	protein homodimerization activity
0.50	GO:0048306	calcium-dependent protein binding
0.36	GO:0008289	lipid binding
0.33	GO:0003723	RNA binding
0.32	GO:0046914	transition metal ion binding

0.52	GO:0045121	membrane raft
0.48	GO:0019897	extrinsic component of plasma membrane
0.46	GO:0005576	extracellular region
0.37	GO:0005783	endoplasmic reticulum
0.36	GO:0031982	vesicle
0.35	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|P60953|CDC42_HUMAN
Cell division control protein 42 homolog
Search

CDC42

0.83	Cell division control protein 42

0.75	GO:0007264	small GTPase mediated signal transduction
0.60	GO:0051301	cell division
0.54	GO:0046847	filopodium assembly
0.53	GO:0038189	neuropilin signaling pathway
0.53	GO:0071338	positive regulation of hair follicle cell proliferation
0.53	GO:0051489	regulation of filopodium assembly
0.52	GO:0060684	epithelial-mesenchymal cell signaling
0.52	GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis
0.52	GO:0120034	positive regulation of plasma membrane bounded cell projection assembly
0.51	GO:0048664	neuron fate determination

0.66	GO:0003924	GTPase activity
0.64	GO:0005525	GTP binding
0.53	GO:0051022	Rho GDP-dissociation inhibitor binding
0.52	GO:0032427	GBD domain binding
0.51	GO:0034191	apolipoprotein A-I receptor binding
0.51	GO:0030742	GTP-dependent protein binding
0.50	GO:0031996	thioesterase binding
0.47	GO:0019901	protein kinase binding
0.46	GO:0061630	ubiquitin protein ligase activity
0.45	GO:0042802	identical protein binding

0.50	GO:0031256	leading edge membrane
0.49	GO:0051233	spindle midzone
0.49	GO:0045335	phagocytic vesicle
0.49	GO:0030496	midbody
0.49	GO:0043197	dendritic spine
0.48	GO:0043209	myelin sheath
0.48	GO:0030175	filopodium
0.48	GO:0072686	mitotic spindle
0.48	GO:0045177	apical part of cell
0.47	GO:0000322	storage vacuole

0.34

GO:0004674

sp|P60981|DEST_HUMAN
Destrin
Search

DSTN

0.94	Destrin, actin depolymerizing factor

0.84	GO:0030042	actin filament depolymerization
0.79	GO:0030836	positive regulation of actin filament depolymerization
0.72	GO:0051014	actin filament severing
0.51	GO:0046716	muscle cell cellular homeostasis
0.50	GO:0045214	sarcomere organization
0.50	GO:0007519	skeletal muscle tissue development
0.37	GO:0006338	chromatin remodeling
0.34	GO:0035722	interleukin-12-mediated signaling pathway
0.34	GO:0001842	neural fold formation
0.34	GO:0044794	positive regulation by host of viral process

0.74	GO:0003779	actin binding
0.55	GO:0032403	protein complex binding
0.34	GO:0046872	metal ion binding
0.33	GO:0005102	receptor binding

0.74	GO:0015629	actin cytoskeleton
0.51	GO:0030863	cortical cytoskeleton
0.50	GO:0030018	Z disc
0.46	GO:0044430	cytoskeletal part
0.40	GO:0016363	nuclear matrix
0.38	GO:0070062	extracellular exosome
0.34	GO:0031258	lamellipodium membrane
0.34	GO:0032587	ruffle membrane
0.34	GO:0005925	focal adhesion
0.33	GO:0005911	cell-cell junction

sp|P60983|GMFB_HUMAN
Glia maturation factor beta
Search

GMFB

0.91	Glia maturation factor gamma

0.85	GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation
0.64	GO:2000249	regulation of actin cytoskeleton reorganization
0.53	GO:0071846	actin filament debranching
0.52	GO:0007612	learning
0.51	GO:0007626	locomotory behavior
0.41	GO:0010469	regulation of receptor activity
0.36	GO:0042325	regulation of phosphorylation
0.36	GO:0051348	negative regulation of transferase activity
0.35	GO:0031400	negative regulation of protein modification process
0.35	GO:0010563	negative regulation of phosphorus metabolic process

0.85	GO:0071933	Arp2/3 complex binding
0.73	GO:0003779	actin binding
0.42	GO:0008083	growth factor activity
0.37	GO:0019207	kinase regulator activity
0.35	GO:0008047	enzyme activator activity
0.35	GO:0004857	enzyme inhibitor activity
0.33	GO:0004871	signal transducer activity

0.45	GO:0005622	intracellular
0.35	GO:0031983	vesicle lumen
0.33	GO:0012505	endomembrane system
0.33	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

sp|P60985|KTDAP_HUMAN
Keratinocyte differentiation-associated protein
Search

KRTDAP

0.97	Keratinocyte differentiation-associated protein isoform 2

0.41

GO:0030154

cell differentiation

0.80	GO:0042599	lamellar body
0.66	GO:0005576	extracellular region

sp|P61006|RAB8A_HUMAN
Ras-related protein Rab-8A
Search

RAB8A

0.92	Oncogene c-mel

0.58	GO:0048210	Golgi vesicle fusion to target membrane
0.54	GO:0006904	vesicle docking involved in exocytosis
0.52	GO:0060271	cilium assembly
0.50	GO:0010506	regulation of autophagy
0.49	GO:0072659	protein localization to plasma membrane
0.47	GO:0017157	regulation of exocytosis
0.45	GO:0048666	neuron development
0.44	GO:0009306	protein secretion
0.43	GO:0032402	melanosome transport
0.43	GO:0032869	cellular response to insulin stimulus

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.56	GO:0031489	myosin V binding
0.56	GO:0019003	GDP binding
0.40	GO:0017137	Rab GTPase binding
0.38	GO:0019901	protein kinase binding
0.36	GO:0071532	ankyrin repeat binding
0.36	GO:0032794	GTPase activating protein binding
0.35	GO:0030911	TPR domain binding
0.35	GO:0005102	receptor binding

0.56	GO:0055038	recycling endosome membrane
0.55	GO:0045335	phagocytic vesicle
0.54	GO:0097546	ciliary base
0.53	GO:0097730	non-motile cilium
0.53	GO:0030133	transport vesicle
0.52	GO:0036064	ciliary basal body
0.51	GO:0005813	centrosome
0.51	GO:0030136	clathrin-coated vesicle
0.50	GO:0005798	Golgi-associated vesicle
0.48	GO:0030667	secretory granule membrane

sp|P61009|SPCS3_HUMAN
Signal peptidase complex subunit 3
Search

SPCS3

0.93	Signal peptidase complex subunit 3

0.76	GO:0006465	signal peptide processing
0.44	GO:0045047	protein targeting to ER

0.59

GO:0008233

peptidase activity

0.79	GO:0005787	signal peptidase complex
0.37	GO:0031090	organelle membrane
0.30	GO:0031224	intrinsic component of membrane

0.59

GO:0008233

sp|P61011|SRP54_HUMAN
Signal recognition particle 54 kDa protein
Search

SRP54

0.62	Signal recognition particle 54 kDa protein (Fragment)

0.75	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.47	GO:0042493	response to drug
0.35	GO:0065002	intracellular protein transmembrane transport
0.35	GO:0043623	cellular protein complex assembly

0.78	GO:0008312	7S RNA binding
0.67	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0030942	endoplasmic reticulum signal peptide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0043021	ribonucleoprotein complex binding
0.40	GO:0008144	drug binding
0.33	GO:0005515	protein binding

0.80	GO:0005786	signal recognition particle, endoplasmic reticulum targeting
0.46	GO:0005829	cytosol
0.44	GO:0005634	nucleus
0.37	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part
0.34	GO:0043232	intracellular non-membrane-bounded organelle

sp|P61018|RAB4B_HUMAN
Ras-related protein Rab-4B
Search

RAB4B

0.76	RAB4A, member RAS oncogene family variant (Fragment)

0.51	GO:0030100	regulation of endocytosis
0.50	GO:0001944	vasculature development
0.46	GO:0019882	antigen processing and presentation
0.42	GO:0015031	protein transport

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0008565	protein transporter activity

0.48	GO:0005768	endosome
0.48	GO:0070062	extracellular exosome
0.48	GO:0032593	insulin-responsive compartment
0.47	GO:0048471	perinuclear region of cytoplasm
0.35	GO:0005739	mitochondrion
0.30	GO:0016020	membrane

sp|P61019|RAB2A_HUMAN
Ras-related protein Rab-2A
Search

RAB2A

0.95	RAB2, member RAS oncogene family

0.63

GO:0007030

Golgi organization

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032553	ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.58

GO:0005794

Golgi apparatus

sp|P61020|RAB5B_HUMAN
Ras-related protein Rab-5B
Search

RAB5B

0.85	Putative rab subfamily protein of small gtpase (Fragment)

0.55	GO:0030100	regulation of endocytosis
0.54	GO:0048227	plasma membrane to endosome transport
0.52	GO:0007032	endosome organization
0.48	GO:0019882	antigen processing and presentation
0.37	GO:0009790	embryo development
0.37	GO:0015031	protein transport
0.36	GO:0090386	phagosome maturation involved in apoptotic cell clearance
0.36	GO:0045176	apical protein localization
0.36	GO:0008340	determination of adult lifespan
0.35	GO:0032940	secretion by cell

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0032561	guanyl ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0030742	GTP-dependent protein binding
0.36	GO:0032794	GTPase activating protein binding
0.34	GO:0020037	heme binding
0.33	GO:0030151	molybdenum ion binding
0.32	GO:0016491	oxidoreductase activity

0.54	GO:0030139	endocytic vesicle
0.52	GO:0005768	endosome
0.50	GO:0070062	extracellular exosome
0.42	GO:0098993	anchored component of synaptic vesicle membrane
0.40	GO:0043231	intracellular membrane-bounded organelle
0.39	GO:0005886	plasma membrane
0.38	GO:0042470	melanosome
0.35	GO:0005938	cell cortex
0.35	GO:0030667	secretory granule membrane
0.34	GO:0005811	lipid droplet

0.32

GO:0016491

sp|P61024|CKS1_HUMAN
Cyclin-dependent kinases regulatory subunit 1
Search

CKS1B

0.68	Cyclin-dependent kinases regulatory subunit

0.76	GO:0045859	regulation of protein kinase activity
0.67	GO:0051301	cell division
0.67	GO:0007049	cell cycle
0.52	GO:0008283	cell proliferation
0.49	GO:0045787	positive regulation of cell cycle
0.49	GO:0016310	phosphorylation
0.49	GO:0033674	positive regulation of kinase activity
0.49	GO:0001934	positive regulation of protein phosphorylation
0.48	GO:0007346	regulation of mitotic cell cycle
0.47	GO:0045893	positive regulation of transcription, DNA-templated

0.82	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity
0.52	GO:0043539	protein serine/threonine kinase activator activity
0.51	GO:0016301	kinase activity
0.50	GO:0043130	ubiquitin binding
0.50	GO:0042393	histone binding
0.49	GO:0019901	protein kinase binding
0.44	GO:0003682	chromatin binding
0.32	GO:0003676	nucleic acid binding

0.51	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.51	GO:0019005	SCF ubiquitin ligase complex
0.33	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

0.82

GO:0016538

sp|P61026|RAB10_HUMAN
Ras-related protein Rab-10
Search

RAB10

0.83	Putative rab subfamily protein of small gtpase

0.59	GO:0097051	establishment of protein localization to endoplasmic reticulum membrane
0.57	GO:0071786	endoplasmic reticulum tubular network organization
0.55	GO:0032869	cellular response to insulin stimulus
0.52	GO:0016197	endosomal transport
0.52	GO:0072659	protein localization to plasma membrane
0.51	GO:0098609	cell-cell adhesion
0.50	GO:0019882	antigen processing and presentation
0.49	GO:0016192	vesicle-mediated transport
0.47	GO:0017157	regulation of exocytosis
0.47	GO:0048468	cell development

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.56	GO:0098641	cadherin binding involved in cell-cell adhesion
0.56	GO:0031489	myosin V binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0051021	GDP-dissociation inhibitor binding

0.60	GO:0032593	insulin-responsive compartment
0.56	GO:0071782	endoplasmic reticulum tubular network
0.55	GO:0055037	recycling endosome
0.54	GO:0005913	cell-cell adherens junction
0.53	GO:0070382	exocytic vesicle
0.52	GO:0005929	cilium
0.51	GO:0005794	Golgi apparatus
0.50	GO:0005789	endoplasmic reticulum membrane
0.43	GO:0005886	plasma membrane
0.42	GO:0030670	phagocytic vesicle membrane

sp|P61073|CXCR4_HUMAN
C-X-C chemokine receptor type 4
Search

CXCR4

0.71	C-X-C motif chemokine receptor 4

0.81	GO:0070098	chemokine-mediated signaling pathway
0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.69	GO:0006935	chemotaxis
0.52	GO:0019722	calcium-mediated signaling
0.51	GO:0001666	response to hypoxia
0.51	GO:0050920	regulation of chemotaxis
0.38	GO:0048714	positive regulation of oligodendrocyte differentiation
0.38	GO:0043217	myelin maintenance
0.37	GO:0016477	cell migration
0.37	GO:0007409	axonogenesis

0.82	GO:0004950	chemokine receptor activity
0.80	GO:0019955	cytokine binding
0.56	GO:0032027	myosin light chain binding
0.51	GO:0043130	ubiquitin binding
0.51	GO:0031625	ubiquitin protein ligase binding
0.48	GO:0003779	actin binding
0.35	GO:0001618	virus receptor activity
0.35	GO:0015026	coreceptor activity
0.32	GO:0008144	drug binding

0.54	GO:0005770	late endosome
0.54	GO:0005769	early endosome
0.53	GO:0005764	lysosome
0.51	GO:0031252	cell leading edge
0.49	GO:0009986	cell surface
0.44	GO:0030054	cell junction
0.42	GO:0043234	protein complex
0.42	GO:0005886	plasma membrane
0.36	GO:0030426	growth cone
0.36	GO:0070062	extracellular exosome

sp|P61077|UB2D3_HUMAN
Ubiquitin-conjugating enzyme E2 D3
Search

UBE2D3

0.59	Ubiquitin-conjugating enzyme

0.50	GO:0000209	protein polyubiquitination
0.46	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.46	GO:0051865	protein autoubiquitination
0.44	GO:0045676	regulation of R7 cell differentiation
0.44	GO:0048132	female germ-line stem cell asymmetric division
0.44	GO:1903955	positive regulation of protein targeting to mitochondrion
0.43	GO:0006513	protein monoubiquitination
0.43	GO:0016322	neuron remodeling
0.43	GO:0030718	germ-line stem cell population maintenance
0.43	GO:0001751	compound eye photoreceptor cell differentiation

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0061631	ubiquitin conjugating enzyme activity
0.41	GO:0031625	ubiquitin protein ligase binding
0.40	GO:0061630	ubiquitin protein ligase activity
0.36	GO:0016874	ligase activity
0.33	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.38	GO:0010008	endosome membrane
0.37	GO:0000151	ubiquitin ligase complex
0.36	GO:0070062	extracellular exosome
0.35	GO:0043234	protein complex
0.34	GO:0005886	plasma membrane
0.34	GO:0005829	cytosol
0.33	GO:0005654	nucleoplasm
0.30	GO:0044425	membrane part

0.36

GO:0016874

sp|P61081|UBC12_HUMAN
NEDD8-conjugating enzyme Ubc12
Search

UBE2M

0.59	Ubiquitin-conjugating enzyme

0.53	GO:0045116	protein neddylation
0.46	GO:0016567	protein ubiquitination
0.40	GO:0043525	positive regulation of neuron apoptotic process
0.35	GO:0038061	NIK/NF-kappaB signaling
0.35	GO:0007179	transforming growth factor beta receptor signaling pathway
0.34	GO:0043687	post-translational protein modification

0.55	GO:0019788	NEDD8 transferase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0004842	ubiquitin-protein transferase activity
0.44	GO:0031625	ubiquitin protein ligase binding
0.44	GO:0061659	ubiquitin-like protein ligase activity
0.39	GO:0016874	ligase activity
0.32	GO:0003676	nucleic acid binding

0.36	GO:0070062	extracellular exosome
0.36	GO:0005737	cytoplasm
0.34	GO:0005654	nucleoplasm

0.39	EC:6	GO:0016874
0.48	KEGG:R03876	GO:0004842

sp|P61086|UBE2K_HUMAN
Ubiquitin-conjugating enzyme E2 K
Search

UBE2K

0.96	Huntingtin interacting protein 2

0.57	GO:0060340	positive regulation of type I interferon-mediated signaling pathway
0.57	GO:0010994	free ubiquitin chain polymerization
0.57	GO:0035458	cellular response to interferon-beta
0.56	GO:0010800	positive regulation of peptidyl-threonine phosphorylation
0.55	GO:0070936	protein K48-linked ubiquitination
0.54	GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process
0.45	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.39	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
0.34	GO:0009107	lipoate biosynthetic process
0.34	GO:0009249	protein lipoylation

0.55	GO:0034450	ubiquitin-ubiquitin ligase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0031625	ubiquitin protein ligase binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0061631	ubiquitin conjugating enzyme activity
0.34	GO:0016992	lipoate synthase activity
0.33	GO:0051539	4 iron, 4 sulfur cluster binding
0.32	GO:0046872	metal ion binding

0.57	GO:0032433	filopodium tip
0.45	GO:0005634	nucleus
0.39	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.34

EC:2.8.1.8

GO:0016992

sp|P61088|UBE2N_HUMAN
Ubiquitin-conjugating enzyme E2 N
Search

UBE2N

0.61	Ubiquitin-conjugating enzyme

0.53	GO:0000209	protein polyubiquitination
0.51	GO:0006301	postreplication repair
0.45	GO:0042769	DNA damage response, detection of DNA damage
0.45	GO:0033182	regulation of histone ubiquitination
0.45	GO:0000729	DNA double-strand break processing
0.44	GO:0045739	positive regulation of DNA repair
0.44	GO:0031058	positive regulation of histone modification
0.44	GO:0050852	T cell receptor signaling pathway
0.44	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.44	GO:0016574	histone ubiquitination

0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0004842	ubiquitin-protein transferase activity
0.48	GO:0031625	ubiquitin protein ligase binding
0.47	GO:0061659	ubiquitin-like protein ligase activity
0.45	GO:0061650	ubiquitin-like protein conjugating enzyme activity
0.43	GO:0043130	ubiquitin binding
0.34	GO:0016874	ligase activity
0.33	GO:0003723	RNA binding

0.47	GO:0031372	UBC13-MMS2 complex
0.46	GO:0035370	UBC13-UEV1A complex
0.44	GO:0005634	nucleus
0.42	GO:0000151	ubiquitin ligase complex
0.39	GO:0043233	organelle lumen
0.37	GO:0043232	intracellular non-membrane-bounded organelle
0.37	GO:0005737	cytoplasm
0.37	GO:0044446	intracellular organelle part
0.37	GO:0070062	extracellular exosome

0.34	EC:6	GO:0016874
0.49	KEGG:R03876	GO:0004842

sp|P61106|RAB14_HUMAN
Ras-related protein Rab-14
Search

RAB14

0.93	RAB14, member RAS oncogene family, like

0.85	GO:0090382	phagosome maturation
0.85	GO:0006895	Golgi to endosome transport
0.84	GO:0032456	endocytic recycling
0.78	GO:0042742	defense response to bacterium
0.65	GO:0008543	fibroblast growth factor receptor signaling pathway
0.60	GO:0009790	embryo development
0.60	GO:0032879	regulation of localization
0.45	GO:0051128	regulation of cellular component organization

0.69	GO:0031489	myosin V binding
0.68	GO:0003924	GTPase activity
0.67	GO:0019003	GDP binding
0.66	GO:0005525	GTP binding

0.83	GO:0045335	phagocytic vesicle
0.83	GO:0055037	recycling endosome
0.79	GO:0005802	trans-Golgi network
0.68	GO:0005829	cytosol

sp|P61129|ZC3H6_HUMAN
Zinc finger CCCH domain-containing protein 6
Search

ZC3H6

0.96	Zinc finger CCCH domain-containing protein 6

0.39	GO:0070245	positive regulation of thymocyte apoptotic process
0.39	GO:0042796	snRNA transcription by RNA polymerase III
0.39	GO:0033085	negative regulation of T cell differentiation in thymus
0.38	GO:0042795	snRNA transcription by RNA polymerase II
0.38	GO:0045945	positive regulation of transcription by RNA polymerase III
0.38	GO:0043029	T cell homeostasis
0.37	GO:0000122	negative regulation of transcription by RNA polymerase II
0.36	GO:0046677	response to antibiotic
0.32	GO:0006915	apoptotic process

0.54	GO:0046872	metal ion binding
0.39	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding
0.38	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.32	GO:0005515	protein binding
0.32	GO:0003723	RNA binding

0.39	GO:0035363	histone locus body
0.38	GO:0015030	Cajal body
0.38	GO:0035327	transcriptionally active chromatin
0.37	GO:0008023	transcription elongation factor complex

sp|P61158|ARP3_HUMAN
Actin-related protein 3
Search

ACTR3

0.85	Actin-related protein 3

0.81	GO:0034314	Arp2/3 complex-mediated actin nucleation
0.55	GO:0016344	meiotic chromosome movement towards spindle pole
0.53	GO:0033206	meiotic cytokinesis
0.52	GO:0071346	cellular response to interferon-gamma
0.52	GO:0008356	asymmetric cell division
0.51	GO:0051653	spindle localization
0.50	GO:0060271	cilium assembly
0.50	GO:0007163	establishment or maintenance of cell polarity
0.36	GO:1905836	response to triterpenoid
0.36	GO:1905834	response to pyrimidine ribonucleotide

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0051015	actin filament binding
0.48	GO:0005200	structural constituent of cytoskeleton
0.35	GO:0051117	ATPase binding

0.80	GO:0005885	Arp2/3 protein complex
0.51	GO:0030027	lamellipodium
0.51	GO:0005903	brush border
0.48	GO:0005911	cell-cell junction
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.36	GO:0061830	concave side of sperm head
0.36	GO:0061828	apical tubulobulbar complex
0.36	GO:0061825	podosome core
0.35	GO:0030056	hemidesmosome

sp|P61160|ARP2_HUMAN
Actin-related protein 2
Search

ACTR2

0.85	Actin-related protein 2 isoform a

0.81	GO:0034314	Arp2/3 complex-mediated actin nucleation
0.54	GO:0016344	meiotic chromosome movement towards spindle pole
0.52	GO:0033206	meiotic cytokinesis
0.51	GO:0071346	cellular response to interferon-gamma
0.51	GO:0008356	asymmetric cell division
0.51	GO:0051653	spindle localization
0.50	GO:0060271	cilium assembly
0.49	GO:0016482	cytosolic transport
0.49	GO:0007163	establishment or maintenance of cell polarity
0.40	GO:0035984	cellular response to trichostatin A

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0003779	actin binding
0.49	GO:0005200	structural constituent of cytoskeleton
0.48	GO:0032403	protein complex binding

0.80	GO:0005885	Arp2/3 protein complex
0.53	GO:0030478	actin cap
0.45	GO:0005829	cytosol
0.41	GO:0061825	podosome core
0.40	GO:0042995	cell projection
0.38	GO:0014069	postsynaptic density
0.38	GO:0031252	cell leading edge
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.35	GO:1904813	ficolin-1-rich granule lumen

sp|P61163|ACTZ_HUMAN
Alpha-centractin
Search

ACTR1A

0.90	Alpha-centractin

0.37	GO:0007283	spermatogenesis
0.37	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.35	GO:0097711	ciliary basal body-plasma membrane docking
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0000086	G2/M transition of mitotic cell cycle
0.34	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.34	GO:0006888	ER to Golgi vesicle-mediated transport

0.51	GO:0032559	adenyl ribonucleotide binding
0.50	GO:0008144	drug binding
0.50	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding

0.82	GO:0005869	dynactin complex
0.56	GO:0005813	centrosome
0.53	GO:0099738	cell cortex region
0.52	GO:0043209	myelin sheath
0.38	GO:0002177	manchette
0.38	GO:0070062	extracellular exosome
0.37	GO:0005814	centriole
0.37	GO:0030137	COPI-coated vesicle
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen

sp|P61165|TM258_HUMAN
Transmembrane protein 258
Search

TMEM258

0.59	Transmembrane domain-containing protein (Fragment)

0.80	GO:0006487	protein N-linked glycosylation
0.36	GO:0015031	protein transport

0.85	GO:0034998	oligosaccharyltransferase I complex
0.30	GO:0031224	intrinsic component of membrane

sp|P61201|CSN2_HUMAN
COP9 signalosome complex subunit 2
Search

COPS2

0.83	COP9 constitutive photomorphogenic homolog subunit 2

0.83	GO:0000338	protein deneddylation
0.82	GO:0035914	skeletal muscle cell differentiation
0.75	GO:0008283	cell proliferation
0.71	GO:0045892	negative regulation of transcription, DNA-templated
0.58	GO:0022008	neurogenesis
0.43	GO:0006357	regulation of transcription by RNA polymerase II
0.38	GO:0043687	post-translational protein modification
0.38	GO:0000715	nucleotide-excision repair, DNA damage recognition
0.38	GO:0006283	transcription-coupled nucleotide-excision repair
0.37	GO:0006366	transcription by RNA polymerase II

0.80	GO:0003714	transcription corepressor activity
0.39	GO:0005515	protein binding
0.36	GO:0004871	signal transducer activity

0.81	GO:0008180	COP9 signalosome
0.48	GO:0005737	cytoplasm
0.36	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

sp|P61204|ARF3_HUMAN
ADP-ribosylation factor 3
Search

ARF3

0.80	ADP ribosylation factor 3

0.53	GO:1990386	mitotic cleavage furrow ingression
0.50	GO:0016192	vesicle-mediated transport
0.49	GO:0098586	cellular response to virus
0.47	GO:0006878	cellular copper ion homeostasis
0.41	GO:0060292	long term synaptic depression
0.41	GO:0097061	dendritic spine organization
0.41	GO:0002090	regulation of receptor internalization
0.41	GO:1903337	positive regulation of vacuolar transport
0.40	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation
0.40	GO:1902822	regulation of late endosome to lysosome transport

0.64	GO:0005525	GTP binding
0.46	GO:0019904	protein domain specific binding
0.45	GO:0046982	protein heterodimerization activity
0.42	GO:0000287	magnesium ion binding
0.41	GO:1990583	phospholipase D activator activity
0.39	GO:0019003	GDP binding
0.34	GO:0003924	GTPase activity
0.34	GO:0005057	signal transducer activity, downstream of receptor
0.33	GO:0003723	RNA binding

0.51	GO:0005794	Golgi apparatus
0.48	GO:0030017	sarcomere
0.47	GO:0031252	cell leading edge
0.43	GO:0005829	cytosol
0.42	GO:0048471	perinuclear region of cytoplasm
0.40	GO:0043234	protein complex
0.39	GO:0014069	postsynaptic density
0.39	GO:0031982	vesicle
0.39	GO:0045211	postsynaptic membrane
0.38	GO:0043005	neuron projection

sp|P61218|RPAB2_HUMAN
DNA-directed RNA polymerases I, II, and III subunit RPABC2
Search

POLR2F

0.93	RNA polymerase II subunit F

0.58	GO:0006351	transcription, DNA-templated
0.35	GO:0035019	somatic stem cell population maintenance
0.35	GO:0032481	positive regulation of type I interferon production
0.35	GO:0060964	regulation of gene silencing by miRNA
0.35	GO:0045815	positive regulation of gene expression, epigenetic
0.35	GO:0008543	fibroblast growth factor receptor signaling pathway
0.34	GO:0016073	snRNA metabolic process
0.34	GO:0050434	positive regulation of viral transcription
0.34	GO:0006283	transcription-coupled nucleotide-excision repair
0.34	GO:0000398	mRNA splicing, via spliceosome

0.70	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.55	GO:0003677	DNA binding
0.33	GO:0004427	inorganic diphosphatase activity
0.33	GO:0000287	magnesium ion binding

0.79	GO:0005665	DNA-directed RNA polymerase II, core complex
0.47	GO:0005736	DNA-directed RNA polymerase I complex
0.47	GO:0005666	DNA-directed RNA polymerase III complex
0.37	GO:0001650	fibrillar center
0.33	GO:0005829	cytosol

0.70	EC:2.7.7.6	GO:0003899
0.33	KEGG:R00004	GO:0004427

sp|P61221|ABCE1_HUMAN
ATP-binding cassette sub-family E member 1
Search

ABCE1

0.92	ATP-binding cassette sub-family E member 1

0.55	GO:0060702	negative regulation of endoribonuclease activity
0.47	GO:0000054	ribosomal subunit export from nucleus
0.44	GO:0006415	translational termination
0.43	GO:0006413	translational initiation
0.34	GO:0060338	regulation of type I interferon-mediated signaling pathway
0.33	GO:0016032	viral process

0.59	GO:0016887	ATPase activity
0.55	GO:0060698	endoribonuclease inhibitor activity
0.53	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0043024	ribosomal small subunit binding
0.41	GO:0005506	iron ion binding
0.33	GO:0051539	4 iron, 4 sulfur cluster binding
0.33	GO:0005515	protein binding

0.48	GO:0005829	cytosol
0.45	GO:0005852	eukaryotic translation initiation factor 3 complex
0.44	GO:0005739	mitochondrion
0.33	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.59

GO:0016887

sp|P61224|RAP1B_HUMAN
Ras-related protein Rap-1b
Search

RAP1B

0.94	RAP1B, member of RAS oncogene family

0.61	GO:0032486	Rap protein signal transduction
0.60	GO:0061028	establishment of endothelial barrier
0.60	GO:0071320	cellular response to cAMP
0.59	GO:1901888	regulation of cell junction assembly
0.58	GO:2000301	negative regulation of synaptic vesicle exocytosis
0.54	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.52	GO:2001214	positive regulation of vasculogenesis
0.49	GO:0010976	positive regulation of neuron projection development
0.48	GO:2000114	regulation of establishment of cell polarity
0.44	GO:0008283	cell proliferation

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.53	GO:0032403	protein complex binding
0.51	GO:0019003	GDP binding
0.46	GO:0017016	Ras GTPase binding
0.44	GO:0008565	protein transporter activity
0.37	GO:0005085	guanyl-nucleotide exchange factor activity
0.36	GO:0017056	structural constituent of nuclear pore
0.35	GO:0004708	MAP kinase kinase activity

0.54	GO:0030054	cell junction
0.50	GO:0032045	guanyl-nucleotide exchange factor complex
0.49	GO:0005811	lipid droplet
0.48	GO:0043209	myelin sheath
0.47	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0043005	neuron projection
0.46	GO:0005829	cytosol
0.41	GO:0005886	plasma membrane
0.39	GO:0031982	vesicle
0.39	GO:0043230	extracellular organelle

0.35

GO:0004708

sp|P61225|RAP2B_HUMAN
Ras-related protein Rap-2b
Search

RAP2B

0.95	RAP2B, member of RAS oncogene family

0.64	GO:0032486	Rap protein signal transduction
0.63	GO:0031954	positive regulation of protein autophosphorylation
0.59	GO:0030336	negative regulation of cell migration
0.58	GO:0061097	regulation of protein tyrosine kinase activity
0.53	GO:0070527	platelet aggregation
0.51	GO:0090557	establishment of endothelial intestinal barrier
0.47	GO:0030033	microvillus assembly
0.45	GO:0048814	regulation of dendrite morphogenesis
0.44	GO:0046328	regulation of JNK cascade
0.43	GO:0072659	protein localization to plasma membrane

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0019904	protein domain specific binding
0.46	GO:0003713	transcription coactivator activity
0.39	GO:0000287	magnesium ion binding

0.62	GO:0055038	recycling endosome membrane
0.59	GO:0044291	cell-cell contact zone
0.56	GO:0005923	bicellular tight junction
0.52	GO:0005829	cytosol
0.51	GO:0070062	extracellular exosome
0.50	GO:0045121	membrane raft
0.45	GO:0005886	plasma membrane
0.38	GO:0030496	midbody
0.36	GO:0070821	tertiary granule membrane
0.35	GO:0035579	specific granule membrane

sp|P61236|YPEL3_HUMAN
Protein yippee-like 3
Search

sp|P61244|MAX_HUMAN
Protein max
Search

MAX

0.95	MYC associated factor X

0.53

GO:0000122

negative regulation of transcription by RNA polymerase II

0.68	GO:0046983	protein dimerization activity
0.57	GO:0070888	E-box binding
0.56	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding
0.56	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.51	GO:0042802	identical protein binding

0.82	GO:0071339	MLL1 complex
0.76	GO:0090575	RNA polymerase II transcription factor complex
0.51	GO:0000790	nuclear chromatin
0.50	GO:0032993	protein-DNA complex

sp|P61247|RS3A_HUMAN
40S ribosomal protein S3a
Search

sp|P61254|RL26_HUMAN
60S ribosomal protein L26
Search

RPL26

0.79	Ribosomal protein L26, pseudogene 2

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.55	GO:1902167	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
0.54	GO:1904803	regulation of translation involved in cellular response to UV
0.54	GO:1902164	positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
0.54	GO:0010467	gene expression
0.53	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
0.53	GO:0009059	macromolecule biosynthetic process
0.52	GO:0042273	ribosomal large subunit biogenesis
0.52	GO:0071480	cellular response to gamma radiation

0.64	GO:0003735	structural constituent of ribosome
0.49	GO:0048027	mRNA 5'-UTR binding
0.34	GO:0005515	protein binding
0.33	GO:0046872	metal ion binding

0.71	GO:0015934	large ribosomal subunit
0.53	GO:0022626	cytosolic ribosome
0.46	GO:0005730	nucleolus
0.45	GO:0005654	nucleoplasm
0.37	GO:0070062	extracellular exosome
0.34	GO:0043195	terminal bouton
0.30	GO:0031224	intrinsic component of membrane

sp|P61266|STX1B_HUMAN
Syntaxin-1B
Search

STX1A

0.56	Syntaxin-4

0.70	GO:0017157	regulation of exocytosis
0.69	GO:0016192	vesicle-mediated transport
0.69	GO:0006886	intracellular protein transport
0.68	GO:0061025	membrane fusion
0.61	GO:0001956	positive regulation of neurotransmitter secretion
0.60	GO:2000463	positive regulation of excitatory postsynaptic potential
0.60	GO:1902803	regulation of synaptic vesicle transport
0.59	GO:0098693	regulation of synaptic vesicle cycle
0.56	GO:0097480	establishment of synaptic vesicle localization
0.56	GO:0099504	synaptic vesicle cycle

0.80	GO:0005484	SNAP receptor activity
0.67	GO:0000149	SNARE binding
0.54	GO:0019900	kinase binding
0.50	GO:0019869	chloride channel inhibitor activity
0.50	GO:0019855	calcium channel inhibitor activity
0.47	GO:0005102	receptor binding
0.44	GO:0017022	myosin binding
0.40	GO:0043008	ATP-dependent protein binding
0.40	GO:0019904	protein domain specific binding
0.39	GO:0048306	calcium-dependent protein binding

0.57	GO:0098793	presynapse
0.55	GO:0030424	axon
0.55	GO:0031201	SNARE complex
0.54	GO:0070382	exocytic vesicle
0.47	GO:0030658	transport vesicle membrane
0.46	GO:0031965	nuclear membrane
0.44	GO:0005886	plasma membrane
0.39	GO:0034705	potassium channel complex
0.39	GO:0042641	actomyosin
0.39	GO:0014069	postsynaptic density

sp|P61278|SMS_HUMAN
Somatostatin
Search

SST

0.97	Preprosomatostatin I

0.76	GO:0010469	regulation of receptor activity
0.56	GO:0030334	regulation of cell migration
0.45	GO:0007267	cell-cell signaling
0.44	GO:0007166	cell surface receptor signaling pathway
0.40	GO:0010447	response to acidic pH
0.40	GO:0006972	hyperosmotic response
0.40	GO:0043200	response to amino acid
0.39	GO:0048545	response to steroid hormone
0.38	GO:0009408	response to heat
0.37	GO:0042493	response to drug

0.79	GO:0005179	hormone activity
0.34	GO:0031878	type 1 somatostatin receptor binding
0.32	GO:0003676	nucleic acid binding

0.66	GO:0005576	extracellular region
0.39	GO:0043025	neuronal cell body
0.30	GO:0016020	membrane

sp|P61289|PSME3_HUMAN
Proteasome activator complex subunit 3
Search

PSME3

0.79	Proteasome activator complex subunit 3

0.55	GO:0010950	positive regulation of endopeptidase activity
0.54	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway
0.53	GO:0061136	regulation of proteasomal protein catabolic process
0.46	GO:2000045	regulation of G1/S transition of mitotic cell cycle
0.39	GO:0006915	apoptotic process
0.39	GO:0009308	amine metabolic process
0.38	GO:0007601	visual perception
0.37	GO:0007049	cell cycle
0.36	GO:0006508	proteolysis
0.36	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition

0.58	GO:0061133	endopeptidase activator activity
0.57	GO:0097371	MDM2/MDM4 family protein binding
0.54	GO:0002039	p53 binding
0.48	GO:0042802	identical protein binding
0.41	GO:0008131	primary amine oxidase activity
0.39	GO:0048038	quinone binding
0.39	GO:0005507	copper ion binding
0.36	GO:0140096	catalytic activity, acting on a protein
0.34	GO:0016787	hydrolase activity
0.33	GO:0016773	phosphotransferase activity, alcohol group as acceptor

0.85	GO:0008537	proteasome activator complex
0.47	GO:0005654	nucleoplasm
0.46	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.41	EC:1.4.3.21	GO:0008131
0.41	KEGG:R01853	GO:0008131

sp|P61296|HAND2_HUMAN
Heart- and neural crest derivatives-expressed protein 2
Search

HAND2

0.95	Heart and neural crest derivatives expressed transcript 1

0.64	GO:0003219	cardiac right ventricle formation
0.62	GO:0060536	cartilage morphogenesis
0.61	GO:2000677	regulation of transcription regulatory region DNA binding
0.60	GO:0043392	negative regulation of DNA binding
0.60	GO:0001947	heart looping
0.59	GO:0043433	negative regulation of DNA binding transcription factor activity
0.59	GO:0042475	odontogenesis of dentin-containing tooth
0.58	GO:0060485	mesenchyme development
0.58	GO:2000764	positive regulation of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis
0.58	GO:2000763	positive regulation of transcription from RNA polymerase II promoter involved in norepinephrine biosynthetic process

0.68	GO:0046983	protein dimerization activity
0.58	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.58	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.55	GO:0003680	AT DNA binding
0.53	GO:0042802	identical protein binding
0.53	GO:0008134	transcription factor binding
0.52	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.49	GO:0003713	transcription coactivator activity
0.48	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.44	GO:0019899	enzyme binding

0.54	GO:0005667	transcription factor complex
0.51	GO:0031981	nuclear lumen
0.49	GO:0000785	chromatin
0.37	GO:0005737	cytoplasm

sp|P61313|RL15_HUMAN
60S ribosomal protein L15
Search

RPL15

0.66	Ribosomal protein L15

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.37	GO:0045471	response to ethanol
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.33	GO:0016072	rRNA metabolic process
0.33	GO:0042254	ribosome biogenesis

0.64	GO:0003735	structural constituent of ribosome
0.47	GO:0045296	cadherin binding
0.40	GO:0003723	RNA binding
0.32	GO:0016787	hydrolase activity

0.61	GO:0005840	ribosome
0.45	GO:0044445	cytosolic part
0.41	GO:0005634	nucleus
0.40	GO:0044446	intracellular organelle part
0.38	GO:0031672	A band
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.32

GO:0016787

sp|P61326|MGN_HUMAN
Protein mago nashi homolog
Search

MAGOH

0.95	Mago homolog B, exon junction complex core component

0.54	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.47	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.47	GO:0008380	RNA splicing
0.42	GO:0051028	mRNA transport
0.40	GO:0006397	mRNA processing
0.38	GO:0006417	regulation of translation
0.36	GO:0006369	termination of RNA polymerase II transcription
0.36	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.35	GO:0031123	RNA 3'-end processing
0.35	GO:0006405	RNA export from nucleus

0.38	GO:0003723	RNA binding
0.35	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.45	GO:0043234	protein complex
0.44	GO:0044446	intracellular organelle part
0.44	GO:1902494	catalytic complex
0.44	GO:0030529	intracellular ribonucleoprotein complex
0.38	GO:0043025	neuronal cell body
0.38	GO:0031974	membrane-enclosed lumen
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P61328|FGF12_HUMAN
Fibroblast growth factor 12
Search

FGF12

0.62	Fibroblast growth factor

0.82	GO:0008543	fibroblast growth factor receptor signaling pathway
0.75	GO:0010469	regulation of receptor activity
0.56	GO:1905150	regulation of voltage-gated sodium channel activity
0.55	GO:0098908	regulation of neuronal action potential
0.53	GO:0010765	positive regulation of sodium ion transport
0.52	GO:0050905	neuromuscular process
0.52	GO:0008344	adult locomotory behavior
0.49	GO:0007268	chemical synaptic transmission
0.40	GO:0007399	nervous system development
0.39	GO:0007254	JNK cascade

0.78	GO:0008083	growth factor activity
0.39	GO:0005104	fibroblast growth factor receptor binding
0.39	GO:0008201	heparin binding
0.39	GO:0017080	sodium channel regulator activity
0.38	GO:0044325	ion channel binding

0.43	GO:0005634	nucleus
0.38	GO:0005576	extracellular region
0.33	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

sp|P61353|RL27_HUMAN
60S ribosomal protein L27
Search

RPL27

0.75	60S ribosomal protein L27

0.59	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.44	GO:0030218	erythrocyte differentiation
0.42	GO:0016072	rRNA metabolic process
0.42	GO:0042254	ribosome biogenesis
0.35	GO:1904044	response to aldosterone
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane

0.63	GO:0003735	structural constituent of ribosome
0.34	GO:0003723	RNA binding
0.32	GO:0016787	hydrolase activity

0.61	GO:0005840	ribosome
0.47	GO:0098556	cytoplasmic side of rough endoplasmic reticulum membrane
0.44	GO:0044445	cytosolic part
0.36	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.34	GO:0005634	nucleus

0.32

GO:0016787

sp|P61366|OSTN_HUMAN
Osteocrin
Search

OSTN

0.97

Osteocrin

0.88	GO:1903860	negative regulation of dendrite extension
0.86	GO:0003416	endochondral bone growth
0.86	GO:0046325	negative regulation of glucose import
0.86	GO:0030828	positive regulation of cGMP biosynthetic process
0.85	GO:0045668	negative regulation of osteoblast differentiation
0.71	GO:0007166	cell surface receptor signaling pathway
0.48	GO:0010469	regulation of receptor activity
0.44	GO:0001503	ossification
0.40	GO:0030500	regulation of bone mineralization

0.72	GO:0005102	receptor binding
0.48	GO:0030545	receptor regulator activity

0.73

GO:0005615

extracellular space

sp|P61371|ISL1_HUMAN
Insulin gene enhancer protein ISL-1
Search

ISL1

0.95	LIM homeodomain transcription factor islet-1

0.64	GO:0048665	neuron fate specification
0.63	GO:0021524	visceral motor neuron differentiation
0.61	GO:0048936	peripheral nervous system neuron axonogenesis
0.60	GO:0031016	pancreas development
0.60	GO:0031290	retinal ganglion cell axon guidance
0.60	GO:0060913	cardiac cell fate determination
0.59	GO:0003139	secondary heart field specification
0.58	GO:0071657	positive regulation of granulocyte colony-stimulating factor production
0.58	GO:0032730	positive regulation of interleukin-1 alpha production
0.58	GO:0048732	gland development

0.64	GO:0043565	sequence-specific DNA binding
0.58	GO:0043425	bHLH transcription factor binding
0.56	GO:0001105	RNA polymerase II transcription coactivator activity
0.56	GO:0001102	RNA polymerase II activating transcription factor binding
0.56	GO:0035326	enhancer binding
0.56	GO:1990841	promoter-specific chromatin binding
0.53	GO:0046872	metal ion binding
0.50	GO:0003690	double-stranded DNA binding
0.40	GO:0016922	ligand-dependent nuclear receptor binding
0.40	GO:0030331	estrogen receptor binding

0.61	GO:0005634	nucleus
0.48	GO:0070013	intracellular organelle lumen
0.43	GO:0044446	intracellular organelle part
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|P61421|VA0D1_HUMAN
V-type proton ATPase subunit d 1
Search

ATP6V0D1

0.68	V-type proton ATPase subunit

0.76	GO:0015991	ATP hydrolysis coupled proton transport
0.54	GO:0036295	cellular response to increased oxygen levels
0.49	GO:0030003	cellular cation homeostasis
0.48	GO:0055072	iron ion homeostasis
0.47	GO:0035675	neuromast hair cell development
0.47	GO:0045851	pH reduction
0.46	GO:0008057	eye pigment granule organization
0.46	GO:0039022	pronephric duct development
0.46	GO:0003406	retinal pigment epithelium development
0.46	GO:0070986	left/right axis specification

0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.51	GO:0036442	proton-exporting ATPase activity
0.49	GO:0015662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
0.42	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
0.36	GO:0032403	protein complex binding

0.79	GO:0033179	proton-transporting V-type ATPase, V0 domain
0.53	GO:0016471	vacuolar proton-transporting V-type ATPase complex
0.52	GO:0005769	early endosome
0.50	GO:0005813	centrosome
0.46	GO:0005765	lysosomal membrane
0.40	GO:0016324	apical plasma membrane
0.38	GO:0043679	axon terminus
0.37	GO:0008021	synaptic vesicle
0.36	GO:0070062	extracellular exosome
0.35	GO:0030670	phagocytic vesicle membrane

sp|P61457|PHS_HUMAN
Pterin-4-alpha-carbinolamine dehydratase
Search

PCBD1

0.80	pterin-4-alpha-carbinolamine dehydratase

0.80	GO:0046146	tetrahydrobiopterin metabolic process
0.80	GO:0034312	diol biosynthetic process
0.72	GO:0042559	pteridine-containing compound biosynthetic process
0.65	GO:0009108	coenzyme biosynthetic process
0.55	GO:0051291	protein heterooligomerization
0.54	GO:0051289	protein homotetramerization
0.40	GO:0055114	oxidation-reduction process
0.39	GO:0043496	regulation of protein homodimerization activity
0.38	GO:0006558	L-phenylalanine metabolic process
0.37	GO:0045893	positive regulation of transcription, DNA-templated

0.81	GO:0008124	4-alpha-hydroxytetrahydrobiopterin dehydratase activity
0.54	GO:0004505	phenylalanine 4-monooxygenase activity
0.49	GO:0042802	identical protein binding
0.38	GO:0003713	transcription coactivator activity

0.48	GO:0005654	nucleoplasm
0.47	GO:0005829	cytosol
0.37	GO:0070062	extracellular exosome

0.81	EC:4.2.1.96	GO:0008124
0.81	KEGG:R04734	GO:0008124

sp|P61513|RL37A_HUMAN
60S ribosomal protein L37a
Search

RPL37A

0.80	Ribosomal protein L37a

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.35	GO:0000733	DNA strand renaturation
0.34	GO:0044265	cellular macromolecule catabolic process
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.33	GO:0034655	nucleobase-containing compound catabolic process
0.33	GO:0016071	mRNA metabolic process

0.64	GO:0003735	structural constituent of ribosome
0.36	GO:0046872	metal ion binding
0.35	GO:0036310	annealing helicase activity
0.34	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.34	GO:0070180	large ribosomal subunit rRNA binding
0.33	GO:0005515	protein binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005840	ribosome
0.35	GO:0005925	focal adhesion
0.35	GO:0070062	extracellular exosome
0.35	GO:0044445	cytosolic part
0.33	GO:0005634	nucleus
0.33	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:3.4.19.12

GO:0036459

sp|P61550|ENVT1_HUMAN
Endogenous retrovirus group S71 member 1 Env polyprotein
Search

0.27	Endogenous retrovirus group S71 member 1 Env polyprotein

0.44	GO:0061025	membrane fusion
0.42	GO:0019062	virion attachment to host cell
0.42	GO:0044803	multi-organism membrane organization
0.42	GO:0030260	entry into host cell
0.32	GO:2001141	regulation of RNA biosynthetic process
0.32	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.32	GO:0010468	regulation of gene expression

0.33	GO:0046872	metal ion binding
0.32	GO:0003676	nucleic acid binding

0.60	GO:0036338	viral membrane
0.42	GO:0020002	host cell plasma membrane
0.41	GO:0055036	virion membrane
0.35	GO:0005886	plasma membrane
0.32	GO:0005622	intracellular
0.30	GO:0044425	membrane part

sp|P61565|ENK21_HUMAN
Endogenous retrovirus group K member 21 Env polyprotein
Search

ENV

0.91	Endogenous retrovirus group K member 6 Env polyprotein

0.69	GO:0045026	plasma membrane fusion
0.41	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.41	GO:0006278	RNA-dependent DNA biosynthetic process
0.41	GO:0015074	DNA integration
0.40	GO:0006310	DNA recombination

0.62	GO:0005198	structural molecule activity
0.42	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.41	GO:0003964	RNA-directed DNA polymerase activity
0.39	GO:0008270	zinc ion binding
0.37	GO:0003677	DNA binding

0.66	GO:0036338	viral membrane
0.53	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

0.42

GO:0004523

sp|P61568|ENK11_HUMAN
Putative endogenous retrovirus group K member 11-1 Env polyprotein
Search

0.22	Putative endogenous retrovirus group K member 11-1 Env polyprotein

0.40

GO:0005198

structural molecule activity

0.66	GO:0036338	viral membrane
0.39	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|P61574|RE113_HUMAN
Endogenous retrovirus group K member 113 Rec protein
Search

0.53	GO:0051028	mRNA transport
0.51	GO:0045026	plasma membrane fusion
0.39	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.38	GO:0051260	protein homooligomerization
0.38	GO:0006405	RNA export from nucleus
0.37	GO:0010628	positive regulation of gene expression
0.34	GO:0010467	gene expression

0.46	GO:0005198	structural molecule activity
0.44	GO:0003723	RNA binding
0.38	GO:0042803	protein homodimerization activity

0.61	GO:0036338	viral membrane
0.51	GO:0005730	nucleolus
0.41	GO:0005886	plasma membrane
0.39	GO:0005737	cytoplasm
0.35	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

sp|P61576|REC04_HUMAN
Endogenous retrovirus group K member 104 Rec protein
Search

0.53	GO:0051028	mRNA transport
0.51	GO:0045026	plasma membrane fusion
0.39	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.38	GO:0051260	protein homooligomerization
0.38	GO:0006405	RNA export from nucleus
0.37	GO:0010628	positive regulation of gene expression
0.34	GO:0010467	gene expression

0.46	GO:0005198	structural molecule activity
0.45	GO:0003723	RNA binding
0.38	GO:0042803	protein homodimerization activity

0.61	GO:0036338	viral membrane
0.51	GO:0005730	nucleolus
0.41	GO:0005886	plasma membrane
0.39	GO:0005737	cytoplasm
0.35	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

sp|P61578|REC16_HUMAN
Endogenous retrovirus group K member 16 Rec protein
Search

0.53	GO:0051028	mRNA transport
0.51	GO:0045026	plasma membrane fusion
0.39	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.38	GO:0051260	protein homooligomerization
0.38	GO:0006405	RNA export from nucleus
0.37	GO:0010628	positive regulation of gene expression
0.34	GO:0010467	gene expression

0.46	GO:0005198	structural molecule activity
0.45	GO:0003723	RNA binding
0.38	GO:0042803	protein homodimerization activity

0.61	GO:0036338	viral membrane
0.52	GO:0005730	nucleolus
0.40	GO:0005886	plasma membrane
0.40	GO:0005737	cytoplasm
0.35	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

sp|P61586|RHOA_HUMAN
Transforming protein RhoA
Search

RHOA

0.87	transforming protein RhoA

0.77	GO:0007264	small GTPase mediated signal transduction
0.76	GO:1902766	skeletal muscle satellite cell migration
0.74	GO:0090505	epiboly involved in wound healing
0.52	GO:0043149	stress fiber assembly
0.52	GO:1904695	positive regulation of vascular smooth muscle contraction
0.51	GO:0001998	angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure
0.51	GO:0043366	beta selection
0.50	GO:0003100	regulation of systemic arterial blood pressure by endothelin
0.50	GO:0090324	negative regulation of oxidative phosphorylation
0.50	GO:0021861	forebrain radial glial cell differentiation

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.44	GO:0017022	myosin binding
0.43	GO:0051022	Rho GDP-dissociation inhibitor binding
0.41	GO:0019003	GDP binding
0.40	GO:0004602	glutathione peroxidase activity
0.40	GO:0019904	protein domain specific binding

0.49	GO:0030027	lamellipodium
0.48	GO:0032587	ruffle membrane
0.47	GO:0097610	cell surface furrow
0.46	GO:0032155	cell division site part
0.46	GO:0043296	apical junction complex
0.45	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.45	GO:0030496	midbody
0.44	GO:0043197	dendritic spine
0.44	GO:0005938	cell cortex
0.44	GO:0005829	cytosol

0.40

EC:1.11.1.9

GO:0004602

sp|P61587|RND3_HUMAN
Rho-related GTP-binding protein RhoE
Search

RND3

0.97	LOW QUALITY PROTEIN: rho-related GTP-binding protein RhoE

0.76	GO:0007264	small GTPase mediated signal transduction
0.34	GO:0048672	positive regulation of collateral sprouting
0.34	GO:0030036	actin cytoskeleton organization
0.34	GO:0007155	cell adhesion

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005515	protein binding

0.45	GO:0005622	intracellular
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.35	GO:0098588	bounding membrane of organelle
0.35	GO:0012505	endomembrane system
0.34	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P61599|NAA20_HUMAN
N-alpha-acetyltransferase 20
Search

NAA20

0.87	N-alpha-acetyltransferase 20, NatB catalytic subunit

0.51	GO:0017196	N-terminal peptidyl-methionine acetylation
0.33	GO:0031167	rRNA methylation

0.67	GO:0008080	N-acetyltransferase activity
0.33	GO:0016433	rRNA (adenine) methyltransferase activity
0.32	GO:0005509	calcium ion binding

0.51	GO:0031416	NatB complex
0.48	GO:0005829	cytosol
0.45	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.67

GO:0008080

sp|P61601|NCALD_HUMAN
Neurocalcin-delta
Search

NCALD

0.92	Kv channel-interacting protein 1

0.54	GO:0003073	regulation of systemic arterial blood pressure
0.53	GO:0019722	calcium-mediated signaling
0.42	GO:0048841	regulation of axon extension involved in axon guidance
0.40	GO:1901385	regulation of voltage-gated calcium channel activity
0.40	GO:0071277	cellular response to calcium ion
0.39	GO:0048839	inner ear development
0.33	GO:0016192	vesicle-mediated transport
0.32	GO:0055085	transmembrane transport

0.70	GO:0005509	calcium ion binding
0.52	GO:0030276	clathrin binding
0.51	GO:0003779	actin binding
0.50	GO:0015631	tubulin binding
0.38	GO:0042802	identical protein binding
0.34	GO:0015276	ligand-gated ion channel activity

0.37	GO:0005622	intracellular
0.36	GO:0070062	extracellular exosome
0.34	GO:0012506	vesicle membrane
0.34	GO:0048475	coated membrane
0.34	GO:0019898	extrinsic component of membrane
0.34	GO:0098805	whole membrane
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0012505	endomembrane system
0.33	GO:0098796	membrane protein complex
0.30	GO:0031224	intrinsic component of membrane

sp|P61604|CH10_HUMAN
10 kDa heat shock protein, mitochondrial
Search

HSPE1

0.85	Heat shock protein, mitochondrial

0.68	GO:0006457	protein folding
0.50	GO:0006986	response to unfolded protein
0.38	GO:0001649	osteoblast differentiation
0.36	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process

0.52	GO:0032559	adenyl ribonucleotide binding
0.52	GO:0051087	chaperone binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0051082	unfolded protein binding
0.39	GO:0046872	metal ion binding
0.35	GO:0003723	RNA binding

0.48	GO:0005737	cytoplasm
0.45	GO:0043233	organelle lumen
0.43	GO:0043231	intracellular membrane-bounded organelle
0.41	GO:0044446	intracellular organelle part
0.38	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

sp|P61619|S61A1_HUMAN
Protein transport protein Sec61 subunit alpha isoform 1
Search

SEC61A1

0.89	Transport protein Sec61 subunit alpha 1

0.64	GO:0015031	protein transport
0.58	GO:0039019	pronephric nephron development
0.52	GO:0007029	endoplasmic reticulum organization
0.51	GO:0072599	establishment of protein localization to endoplasmic reticulum
0.51	GO:0016049	cell growth
0.48	GO:0046907	intracellular transport
0.48	GO:0090150	establishment of protein localization to membrane
0.39	GO:0034341	response to interferon-gamma
0.37	GO:0021986	habenula development
0.35	GO:0036498	IRE1-mediated unfolded protein response

0.48	GO:0043022	ribosome binding
0.34	GO:0005515	protein binding
0.33	GO:0022857	transmembrane transporter activity

0.50	GO:0005789	endoplasmic reticulum membrane
0.38	GO:0005791	rough endoplasmic reticulum
0.35	GO:0030670	phagocytic vesicle membrane
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|P61626|LYSC_HUMAN
Lysozyme C
Search

LYZ

0.52	Lysozyme C, non-stomach isozyme

0.78	GO:0042742	defense response to bacterium
0.77	GO:0019835	cytolysis
0.48	GO:0031640	killing of cells of other organism
0.43	GO:0016998	cell wall macromolecule catabolic process
0.42	GO:0007586	digestion
0.36	GO:0001895	retina homeostasis
0.35	GO:0043312	neutrophil degranulation
0.35	GO:0019730	antimicrobial humoral response
0.34	GO:0006954	inflammatory response
0.33	GO:0044267	cellular protein metabolic process

0.78	GO:0003796	lysozyme activity
0.46	GO:0042802	identical protein binding
0.32	GO:0003735	structural constituent of ribosome

0.49	GO:0005576	extracellular region
0.36	GO:0030141	secretory granule
0.35	GO:0005766	primary lysosome
0.35	GO:0060205	cytoplasmic vesicle lumen
0.35	GO:0005775	vacuolar lumen
0.35	GO:0048237	rough endoplasmic reticulum lumen
0.34	GO:0000137	Golgi cis cisterna
0.34	GO:0005902	microvillus
0.34	GO:0030140	trans-Golgi network transport vesicle
0.32	GO:0005840	ribosome

0.78

EC:3.2.1.17

GO:0003796

sp|P61647|SIA8F_HUMAN
Alpha-2,8-sialyltransferase 8F
Search

ST8SIA6

0.97	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6

0.83	GO:0097503	sialylation
0.74	GO:0006486	protein glycosylation
0.60	GO:0001574	ganglioside biosynthetic process
0.50	GO:0009311	oligosaccharide metabolic process
0.48	GO:0016051	carbohydrate biosynthetic process
0.36	GO:0034605	cellular response to heat
0.35	GO:0008284	positive regulation of cell proliferation
0.35	GO:0021628	olfactory nerve formation
0.35	GO:0071699	olfactory placode morphogenesis

0.84

GO:0008373

sialyltransferase activity

0.69	GO:0005794	Golgi apparatus
0.37	GO:0098588	bounding membrane of organelle
0.37	GO:0031984	organelle subcompartment
0.30	GO:0031224	intrinsic component of membrane

0.84

EC:2.4.99

GO:0008373

sp|P61758|PFD3_HUMAN
Prefoldin subunit 3
Search

VBP1

0.72	Prefoldin subunit 3

0.67	GO:0006457	protein folding
0.46	GO:0007021	tubulin complex assembly
0.42	GO:0007017	microtubule-based process

0.43

GO:0015631

tubulin binding

0.78	GO:0016272	prefoldin complex
0.45	GO:0005829	cytosol
0.45	GO:0005844	polysome
0.40	GO:0043227	membrane-bounded organelle
0.39	GO:0043229	intracellular organelle
0.30	GO:0031224	intrinsic component of membrane

sp|P61764|STXB1_HUMAN
Syntaxin-binding protein 1
Search

STXBP1

0.94	Syntaxin-binding protein 1

0.80	GO:0006904	vesicle docking involved in exocytosis
0.54	GO:0032229	negative regulation of synaptic transmission, GABAergic
0.54	GO:0002576	platelet degranulation
0.53	GO:0099011	neuronal dense core vesicle exocytosis
0.53	GO:0007412	axon target recognition
0.53	GO:0070527	platelet aggregation
0.52	GO:0016188	synaptic vesicle maturation
0.52	GO:0060292	long term synaptic depression
0.52	GO:0045956	positive regulation of calcium ion-dependent exocytosis
0.51	GO:0007274	neuromuscular synaptic transmission

0.53	GO:0017075	syntaxin-1 binding
0.39	GO:0043274	phospholipase binding
0.38	GO:0047485	protein N-terminus binding
0.37	GO:0019901	protein kinase binding
0.37	GO:0019904	protein domain specific binding
0.36	GO:0042802	identical protein binding
0.34	GO:0003723	RNA binding

0.54	GO:0048787	presynaptic active zone membrane
0.53	GO:0031091	platelet alpha granule
0.50	GO:0045335	phagocytic vesicle
0.49	GO:0043209	myelin sheath
0.48	GO:0030424	axon
0.47	GO:0005829	cytosol
0.47	GO:0005654	nucleoplasm
0.42	GO:0005739	mitochondrion
0.38	GO:0043679	axon terminus
0.37	GO:0048471	perinuclear region of cytoplasm

sp|P61769|B2MG_HUMAN
Beta-2-microglobulin
Search

B2M

0.87	Beta-2-microglobulin

0.81	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I
0.74	GO:0006955	immune response
0.56	GO:1904440	positive regulation of ferrous iron import across plasma membrane
0.56	GO:1904434	positive regulation of ferrous iron binding
0.56	GO:1904435	regulation of transferrin receptor binding
0.56	GO:0071283	cellular response to iron(III) ion
0.56	GO:0002481	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
0.55	GO:1900122	positive regulation of receptor binding
0.54	GO:0002726	positive regulation of T cell cytokine production
0.54	GO:1900121	negative regulation of receptor binding

0.48	GO:0042802	identical protein binding
0.32	GO:0046872	metal ion binding

0.81	GO:0042612	MHC class I protein complex
0.66	GO:0005576	extracellular region
0.54	GO:1990712	HFE-transferrin receptor complex
0.50	GO:0009897	external side of plasma membrane
0.47	GO:0005794	Golgi apparatus
0.46	GO:0005829	cytosol
0.37	GO:0030670	phagocytic vesicle membrane
0.36	GO:0005925	focal adhesion
0.36	GO:0031905	early endosome lumen
0.36	GO:1904724	tertiary granule lumen

sp|P61803|DAD1_HUMAN
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1
Search

DAD1

0.85	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1

0.74	GO:0006486	protein glycosylation
0.53	GO:0001824	blastocyst development
0.52	GO:0043066	negative regulation of apoptotic process
0.42	GO:0006915	apoptotic process
0.37	GO:0007584	response to nutrient
0.36	GO:0042493	response to drug
0.35	GO:0018196	peptidyl-asparagine modification
0.34	GO:0009409	response to cold
0.34	GO:0007623	circadian rhythm
0.33	GO:0009408	response to heat

0.84	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity
0.33	GO:0016681	oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor
0.32	GO:0009055	electron transfer activity

0.83	GO:0008250	oligosaccharyltransferase complex
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.84

EC:2.4.1.119

GO:0004579

sp|P61812|TGFB2_HUMAN
Transforming growth factor beta-2
Search

TGFB2

0.85	Transforming growth factor beta-2

0.80	GO:0016049	cell growth
0.74	GO:0010469	regulation of receptor activity
0.67	GO:0051795	positive regulation of timing of catagen
0.67	GO:0045726	positive regulation of integrin biosynthetic process
0.67	GO:0010693	negative regulation of alkaline phosphatase activity
0.66	GO:0051891	positive regulation of cardioblast differentiation
0.66	GO:0010936	negative regulation of macrophage cytokine production
0.66	GO:0032909	regulation of transforming growth factor beta2 production
0.65	GO:0060389	pathway-restricted SMAD protein phosphorylation
0.65	GO:0060038	cardiac muscle cell proliferation

0.85	GO:0005160	transforming growth factor beta receptor binding
0.77	GO:0008083	growth factor activity
0.63	GO:0001540	amyloid-beta binding
0.56	GO:0042803	protein homodimerization activity
0.44	GO:0005125	cytokine activity
0.35	GO:0004702	signal transducer, downstream of receptor, with serine/threonine kinase activity
0.35	GO:0046982	protein heterodimerization activity

0.72	GO:0005615	extracellular space
0.56	GO:0031012	extracellular matrix
0.41	GO:0043025	neuronal cell body
0.41	GO:0030424	axon
0.36	GO:0031093	platelet alpha granule lumen
0.35	GO:0005768	endosome

0.35

GO:0004702

sp|P61916|NPC2_HUMAN
Epididymal secretory protein E1
Search

NPC2

0.93	NPC intracellular cholesterol transporter 2

0.85	GO:0032367	intracellular cholesterol transport
0.57	GO:0033344	cholesterol efflux
0.54	GO:0042632	cholesterol homeostasis
0.50	GO:0009615	response to virus
0.43	GO:0008203	cholesterol metabolic process
0.36	GO:0046836	glycolipid transport
0.36	GO:0034383	low-density lipoprotein particle clearance
0.36	GO:0043312	neutrophil degranulation
0.36	GO:0019747	regulation of isoprenoid metabolic process
0.35	GO:0015914	phospholipid transport

0.55	GO:0015485	cholesterol binding
0.55	GO:0017127	cholesterol transporter activity
0.48	GO:0019899	enzyme binding

0.52	GO:0005764	lysosome
0.49	GO:0005615	extracellular space
0.40	GO:0005783	endoplasmic reticulum
0.38	GO:1903561	extracellular vesicle
0.36	GO:0034774	secretory granule lumen
0.35	GO:0005775	vacuolar lumen

sp|P61923|COPZ1_HUMAN
Coatomer subunit zeta-1
Search

COPZ1

0.92	Coatomer protein complex subunit zeta

0.65	GO:0015031	protein transport
0.62	GO:0016192	vesicle-mediated transport
0.62	GO:0046907	intracellular transport
0.62	GO:0034613	cellular protein localization
0.48	GO:1901998	toxin transport
0.45	GO:0002088	lens development in camera-type eye

0.34

GO:0003723

RNA binding

0.68	GO:0030117	membrane coat
0.51	GO:0030663	COPI-coated vesicle membrane
0.48	GO:0044431	Golgi apparatus part
0.37	GO:0031984	organelle subcompartment
0.35	GO:0030133	transport vesicle
0.35	GO:0019028	viral capsid
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.35	GO:0044432	endoplasmic reticulum part
0.34	GO:0005829	cytosol
0.34	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane

sp|P61925|IPKA_HUMAN
cAMP-dependent protein kinase inhibitor alpha
Search

PKIA

0.97	cAMP-dependent protein kinase inhibitor alpha

0.81	GO:0071901	negative regulation of protein serine/threonine kinase activity
0.65	GO:2000479	regulation of cAMP-dependent protein kinase activity
0.60	GO:0042308	negative regulation of protein import into nucleus
0.58	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.56	GO:0000122	negative regulation of transcription by RNA polymerase II
0.51	GO:0016310	phosphorylation

0.85	GO:0004862	cAMP-dependent protein kinase inhibitor activity
0.63	GO:0034236	protein kinase A catalytic subunit binding
0.53	GO:0016301	kinase activity

0.48	GO:0005634	nucleus
0.41	GO:0005737	cytoplasm

sp|P61927|RL37_HUMAN
60S ribosomal protein L37
Search

RPL37

0.73	Ribosomal protein L37

0.59	GO:0043043	peptide biosynthetic process
0.54	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.33	GO:0016072	rRNA metabolic process
0.33	GO:0042254	ribosome biogenesis

0.63	GO:0019843	rRNA binding
0.62	GO:0003735	structural constituent of ribosome
0.52	GO:0046872	metal ion binding
0.34	GO:0019838	growth factor binding

0.60	GO:0005840	ribosome
0.44	GO:0044445	cytosolic part
0.39	GO:0044446	intracellular organelle part
0.35	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|P61952|GBG11_HUMAN
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
Search

GNG11

0.70	Guanine nucleotide-binding protein subunit gamma

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.49	GO:0042462	eye photoreceptor cell development
0.47	GO:0007602	phototransduction
0.42	GO:0008104	protein localization
0.38	GO:0010659	cardiac muscle cell apoptotic process
0.37	GO:0071456	cellular response to hypoxia
0.35	GO:0071377	cellular response to glucagon stimulus
0.35	GO:0022400	regulation of rhodopsin mediated signaling pathway
0.34	GO:0071482	cellular response to light stimulus
0.34	GO:0009584	detection of visible light

0.64	GO:0004871	signal transducer activity
0.42	GO:0003924	GTPase activity
0.34	GO:0005515	protein binding
0.34	GO:0003995	acyl-CoA dehydrogenase activity
0.33	GO:0050660	flavin adenine dinucleotide binding

0.81	GO:1905360	GTPase complex
0.80	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.66	GO:0098797	plasma membrane protein complex
0.38	GO:0001750	photoreceptor outer segment
0.37	GO:0001917	photoreceptor inner segment
0.36	GO:0060170	ciliary membrane

0.34

EC:1.3.99.3

GO:0003995

sp|P61956|SUMO2_HUMAN
Small ubiquitin-related modifier 2
Search

SUMO2

0.75	Small ubiquitin-related modifier

0.80	GO:0016925	protein sumoylation
0.43	GO:1903052	positive regulation of proteolysis involved in cellular protein catabolic process
0.42	GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process
0.42	GO:0043392	negative regulation of DNA binding
0.39	GO:0060216	definitive hemopoiesis
0.38	GO:0043009	chordate embryonic development
0.37	GO:1903322	positive regulation of protein modification by small protein conjugation or removal
0.37	GO:0070911	global genome nucleotide-excision repair
0.36	GO:2000058	regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.36	GO:0034504	protein localization to nucleus

0.49	GO:0031386	protein tag
0.44	GO:0001222	transcription corepressor binding
0.43	GO:0019899	enzyme binding
0.38	GO:0019789	SUMO transferase activity
0.35	GO:0046965	retinoid X receptor binding
0.33	GO:0003723	RNA binding

0.60	GO:0005634	nucleus
0.42	GO:0031974	membrane-enclosed lumen
0.39	GO:0044446	intracellular organelle part
0.36	GO:0070062	extracellular exosome
0.34	GO:0005737	cytoplasm
0.33	GO:0005694	chromosome
0.33	GO:0043234	protein complex

sp|P61960|UFM1_HUMAN
Ubiquitin-fold modifier 1
Search

UFM1

0.90	Ubiquitin-fold modifier 1

0.86	GO:0071569	protein ufmylation
0.71	GO:0033146	regulation of intracellular estrogen receptor signaling pathway
0.69	GO:0034976	response to endoplasmic reticulum stress
0.44	GO:0043066	negative regulation of apoptotic process
0.40	GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus
0.33	GO:0055114	oxidation-reduction process

0.38	GO:0005515	protein binding
0.35	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

0.61	GO:0005634	nucleus
0.57	GO:0005783	endoplasmic reticulum
0.42	GO:0070062	extracellular exosome

0.35

EC:1.2.1

GO:0016620

sp|P61962|DCAF7_HUMAN
DDB1- and CUL4-associated factor 7
Search

DCAF7

0.94	WD repeat-containing protein 68

0.55	GO:0048703	embryonic viscerocranium morphogenesis
0.53	GO:0051216	cartilage development
0.51	GO:0048627	myoblast development
0.50	GO:0035332	positive regulation of hippo signaling
0.48	GO:0048747	muscle fiber development
0.47	GO:0045927	positive regulation of growth
0.47	GO:0007517	muscle organ development
0.38	GO:0016567	protein ubiquitination
0.37	GO:0043687	post-translational protein modification
0.36	GO:0016573	histone acetylation

0.40	GO:0008241	peptidyl-dipeptidase activity
0.38	GO:0004180	carboxypeptidase activity
0.38	GO:0005515	protein binding
0.37	GO:0008237	metallopeptidase activity
0.37	GO:0004402	histone acetyltransferase activity
0.35	GO:0005249	voltage-gated potassium channel activity
0.35	GO:0016875	ligase activity, forming carbon-oxygen bonds
0.35	GO:0140101	catalytic activity, acting on a tRNA
0.35	GO:0030554	adenyl nucleotide binding
0.35	GO:0004672	protein kinase activity

0.69	GO:0016363	nuclear matrix
0.69	GO:0080008	Cul4-RING E3 ubiquitin ligase complex
0.64	GO:0016604	nuclear body
0.58	GO:0005829	cytosol
0.51	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.40

EC:3.4.15

GO:0008241

sp|P61964|WDR5_HUMAN
WD repeat-containing protein 5
Search

WDR5

0.92	WD repeat-containing protein 5

0.77	GO:0043982	histone H4-K8 acetylation
0.77	GO:0043981	histone H4-K5 acetylation
0.76	GO:0043984	histone H4-K16 acetylation
0.75	GO:0051568	histone H3-K4 methylation
0.73	GO:0035948	positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter
0.71	GO:0043966	histone H3 acetylation
0.66	GO:0001501	skeletal system development
0.61	GO:0060271	cilium assembly
0.52	GO:0007482	haltere development
0.49	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process

0.78	GO:0043996	histone acetyltransferase activity (H4-K8 specific)
0.78	GO:0046972	histone acetyltransferase activity (H4-K16 specific)
0.78	GO:0043995	histone acetyltransferase activity (H4-K5 specific)
0.71	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.71	GO:0140034	methylation-dependent protein binding
0.68	GO:0042393	histone binding
0.36	GO:0003743	translation initiation factor activity

0.77	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex
0.76	GO:0044666	MLL3/4 complex
0.73	GO:0048188	Set1C/COMPASS complex
0.72	GO:0044665	MLL1/2 complex
0.63	GO:0036064	ciliary basal body
0.52	GO:0044545	NSL complex
0.36	GO:0019013	viral nucleocapsid
0.35	GO:0030529	intracellular ribonucleoprotein complex
0.30	GO:0016021	integral component of membrane

sp|P61966|AP1S1_HUMAN
AP-1 complex subunit sigma-1A
Search

AP1S1

0.56	AP complex subunit sigma

0.68	GO:0006886	intracellular protein transport
0.67	GO:0016192	vesicle-mediated transport
0.49	GO:0016482	cytosolic transport
0.49	GO:0016197	endosomal transport
0.48	GO:0009615	response to virus
0.43	GO:0030198	extracellular matrix organization
0.41	GO:0007399	nervous system development
0.35	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.35	GO:0060612	adipose tissue development
0.34	GO:0008542	visual learning

0.69	GO:0008565	protein transporter activity
0.33	GO:0005515	protein binding
0.32	GO:0016874	ligase activity

0.74	GO:0030117	membrane coat
0.52	GO:0043195	terminal bouton
0.46	GO:0005794	Golgi apparatus
0.45	GO:0005829	cytosol
0.43	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0005905	clathrin-coated pit
0.37	GO:0031982	vesicle
0.37	GO:0005886	plasma membrane
0.36	GO:0043230	extracellular organelle
0.35	GO:0005615	extracellular space

0.32

GO:0016874

sp|P61968|LMO4_HUMAN
LIM domain transcription factor LMO4
Search

LMO4

0.97	LOW QUALITY PROTEIN: LIM domain transcription factor LMO4

0.57	GO:0021527	spinal cord association neuron differentiation
0.56	GO:0021514	ventral spinal cord interneuron differentiation
0.56	GO:0042659	regulation of cell fate specification
0.55	GO:0021522	spinal cord motor neuron differentiation
0.55	GO:0048538	thymus development
0.55	GO:0003281	ventricular septum development
0.54	GO:0001843	neural tube closure
0.52	GO:0031333	negative regulation of protein complex assembly
0.52	GO:0030334	regulation of cell migration
0.51	GO:0033674	positive regulation of kinase activity

0.55	GO:0001158	enhancer sequence-specific DNA binding
0.54	GO:0046872	metal ion binding
0.49	GO:0008134	transcription factor binding
0.37	GO:0003712	transcription cofactor activity
0.33	GO:0003700	DNA binding transcription factor activity

0.52	GO:0031252	cell leading edge
0.50	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

sp|P61970|NTF2_HUMAN
Nuclear transport factor 2
Search

NUTF2

0.77	Nuclear transport factor 2

0.85	GO:0000060	protein import into nucleus, translocation
0.84	GO:0006611	protein export from nucleus
0.59	GO:0090204	protein localization to nuclear pore
0.52	GO:1904046	negative regulation of vascular endothelial growth factor production
0.49	GO:0051028	mRNA transport
0.48	GO:0042307	positive regulation of protein import into nucleus
0.36	GO:0010469	regulation of receptor activity

0.79	GO:0008536	Ran GTPase binding
0.78	GO:0005487	structural constituent of nuclear pore
0.72	GO:0042802	identical protein binding
0.55	GO:0008565	protein transporter activity
0.50	GO:0061608	nuclear import signal receptor activity
0.37	GO:0005179	hormone activity

0.68	GO:0005654	nucleoplasm
0.67	GO:0005829	cytosol
0.56	GO:0005640	nuclear outer membrane
0.52	GO:0005637	nuclear inner membrane
0.52	GO:0005643	nuclear pore
0.44	GO:0070062	extracellular exosome
0.34	GO:0036338	viral membrane

sp|P61978|HNRPK_HUMAN
Heterogeneous nuclear ribonucleoprotein K
Search

HNRNPK

0.86	Heterogeneous nuclear ribonucleoprotein K transcript variant

0.69	GO:0006357	regulation of transcription by RNA polymerase II
0.62	GO:0006396	RNA processing
0.55	GO:0045716	positive regulation of low-density lipoprotein particle receptor biosynthetic process
0.54	GO:1902165	regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
0.54	GO:0048025	negative regulation of mRNA splicing, via spliceosome
0.53	GO:0010988	regulation of low-density lipoprotein particle clearance
0.52	GO:0048260	positive regulation of receptor-mediated endocytosis
0.51	GO:0032368	regulation of lipid transport
0.48	GO:0043066	negative regulation of apoptotic process
0.48	GO:0045893	positive regulation of transcription, DNA-templated

0.58	GO:0003723	RNA binding
0.54	GO:0003677	DNA binding
0.50	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.50	GO:0045296	cadherin binding
0.48	GO:0019904	protein domain specific binding
0.47	GO:0001067	regulatory region nucleic acid binding
0.47	GO:0042802	identical protein binding
0.36	GO:0005521	lamin binding
0.36	GO:0051117	ATPase binding
0.35	GO:0042805	actinin binding

0.60	GO:0019013	viral nucleocapsid
0.55	GO:0030529	intracellular ribonucleoprotein complex
0.47	GO:0000790	nuclear chromatin
0.47	GO:0005654	nucleoplasm
0.44	GO:0002102	podosome
0.42	GO:1902494	catalytic complex
0.41	GO:0030054	cell junction
0.40	GO:0042995	cell projection
0.37	GO:0031012	extracellular matrix
0.37	GO:0070062	extracellular exosome

sp|P61981|1433G_HUMAN
14-3-3 protein gamma
Search

YWHAG

0.97	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma

0.51	GO:0048167	regulation of synaptic plasticity
0.50	GO:0045664	regulation of neuron differentiation
0.45	GO:0006605	protein targeting
0.40	GO:0007507	heart development
0.40	GO:0007420	brain development
0.38	GO:0032869	cellular response to insulin stimulus
0.37	GO:0055114	oxidation-reduction process
0.35	GO:1900739	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
0.35	GO:0097711	ciliary basal body-plasma membrane docking
0.35	GO:1901030	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

0.77	GO:0019904	protein domain specific binding
0.53	GO:0005159	insulin-like growth factor receptor binding
0.52	GO:0005080	protein kinase C binding
0.47	GO:0042802	identical protein binding
0.42	GO:0004497	monooxygenase activity
0.39	GO:0030971	receptor tyrosine kinase binding
0.35	GO:0008426	protein kinase C inhibitor activity
0.35	GO:0003779	actin binding
0.34	GO:0070003	threonine-type peptidase activity
0.33	GO:0003723	RNA binding

0.50	GO:0043209	myelin sheath
0.37	GO:0005622	intracellular
0.37	GO:0031982	vesicle
0.36	GO:0005925	focal adhesion
0.36	GO:0043230	extracellular organelle
0.35	GO:0005615	extracellular space
0.34	GO:0031090	organelle membrane
0.34	GO:1905369	endopeptidase complex
0.33	GO:0043234	protein complex

sp|P62068|UBP46_HUMAN
Ubiquitin carboxyl-terminal hydrolase 46
Search

USP46

0.95	Ubiquitin carboxyl-terminal hydrolase 46

0.75	GO:0016579	protein deubiquitination
0.72	GO:0006511	ubiquitin-dependent protein catabolic process
0.52	GO:0060013	righting reflex
0.52	GO:0032228	regulation of synaptic transmission, GABAergic
0.51	GO:0008343	adult feeding behavior
0.51	GO:0001662	behavioral fear response
0.51	GO:0048149	behavioral response to ethanol
0.35	GO:0050862	positive regulation of T cell receptor signaling pathway

0.75	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
0.34	GO:0046872	metal ion binding
0.34	GO:0004197	cysteine-type endopeptidase activity
0.33	GO:0005515	protein binding

0.33	GO:0005829	cytosol
0.33	GO:0005634	nucleus

0.75

EC:3.4.19.12

GO:0036459

sp|P62070|RRAS2_HUMAN
Ras-related protein R-Ras2
Search

RRAS2

0.97	Related RAS viral (r-ras) oncogene homolog 2

0.61	GO:0007165	signal transduction
0.51	GO:1901214	regulation of neuron death
0.51	GO:0030335	positive regulation of cell migration
0.38	GO:0001649	osteoblast differentiation
0.34	GO:0060325	face morphogenesis
0.34	GO:0045199	maintenance of epithelial cell apical/basal polarity
0.34	GO:0051896	regulation of protein kinase B signaling
0.34	GO:0045766	positive regulation of angiogenesis
0.34	GO:0030336	negative regulation of cell migration
0.34	GO:0070372	regulation of ERK1 and ERK2 cascade

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005515	protein binding
0.34	GO:0004767	sphingomyelin phosphodiesterase activity
0.33	GO:0044877	macromolecular complex binding
0.33	GO:0005198	structural molecule activity

0.37	GO:0005925	focal adhesion
0.37	GO:0070062	extracellular exosome
0.36	GO:0005622	intracellular
0.34	GO:0012505	endomembrane system
0.34	GO:0012506	vesicle membrane
0.34	GO:0048475	coated membrane
0.34	GO:0098805	whole membrane
0.34	GO:0098588	bounding membrane of organelle
0.33	GO:0005886	plasma membrane
0.33	GO:0098796	membrane protein complex

0.34	EC:3.1.4.12	GO:0004767
0.34	KEGG:R02541	GO:0004767

sp|P62072|TIM10_HUMAN
Mitochondrial import inner membrane translocase subunit Tim10
Search

TIMM10

0.85	Translocase of inner mitochondrial membrane 10

0.79	GO:0045039	protein import into mitochondrial inner membrane
0.56	GO:0072321	chaperone-mediated protein transport
0.35	GO:0007605	sensory perception of sound

0.64	GO:0008565	protein transporter activity
0.51	GO:0046872	metal ion binding
0.51	GO:0051087	chaperone binding
0.50	GO:0042803	protein homodimerization activity

0.78	GO:0042721	mitochondrial inner membrane protein insertion complex
0.76	GO:0042719	mitochondrial intermembrane space protein transporter complex
0.35	GO:0005744	mitochondrial inner membrane presequence translocase complex

sp|P62079|TSN5_HUMAN
Tetraspanin-5
Search

TSPAN5

0.59	Tetraspanin

0.52	GO:0045747	positive regulation of Notch signaling pathway
0.51	GO:0072659	protein localization to plasma membrane
0.47	GO:0051604	protein maturation
0.43	GO:0007166	cell surface receptor signaling pathway
0.34	GO:0008283	cell proliferation
0.34	GO:0007155	cell adhesion

0.47

GO:0019899

enzyme binding

0.42

GO:0005887

integral component of plasma membrane

sp|P62081|RS7_HUMAN
40S ribosomal protein S7
Search

RPS7

0.61	40S ribosomal protein S7

0.60	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.49	GO:1902255	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator
0.48	GO:2000059	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.48	GO:1904667	negative regulation of ubiquitin protein ligase activity
0.48	GO:0042274	ribosomal small subunit biogenesis
0.46	GO:0043009	chordate embryonic development
0.46	GO:0016072	rRNA metabolic process

0.63	GO:0003735	structural constituent of ribosome
0.49	GO:1990948	ubiquitin ligase inhibitor activity
0.46	GO:0003730	mRNA 3'-UTR binding
0.46	GO:0048027	mRNA 5'-UTR binding
0.45	GO:0019901	protein kinase binding
0.35	GO:0008266	poly(U) RNA binding
0.33	GO:0016787	hydrolase activity

0.61	GO:0005840	ribosome
0.47	GO:0044445	cytosolic part
0.46	GO:0030686	90S preribosome
0.46	GO:0032040	small-subunit processome
0.45	GO:0005815	microtubule organizing center
0.43	GO:0005730	nucleolus
0.39	GO:0043234	protein complex
0.36	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome

0.33

GO:0016787

sp|P62136|PP1A_HUMAN
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
Search

PPP1CA

0.50	Serine/threonine-protein phosphatase

0.72	GO:0006470	protein dephosphorylation
0.60	GO:0043153	entrainment of circadian clock by photoperiod
0.59	GO:0032922	circadian regulation of gene expression
0.53	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
0.50	GO:0048754	branching morphogenesis of an epithelial tube
0.50	GO:0030324	lung development
0.47	GO:0046822	regulation of nucleocytoplasmic transport
0.47	GO:0098609	cell-cell adhesion
0.41	GO:0005977	glycogen metabolic process
0.40	GO:0010288	response to lead ion

0.77	GO:0004722	protein serine/threonine phosphatase activity
0.53	GO:0046872	metal ion binding
0.52	GO:0098641	cadherin binding involved in cell-cell adhesion
0.49	GO:0047485	protein N-terminus binding
0.46	GO:0019901	protein kinase binding
0.42	GO:0008157	protein phosphatase 1 binding
0.40	GO:0032403	protein complex binding
0.39	GO:0005521	lamin binding
0.38	GO:0008022	protein C-terminus binding
0.37	GO:0019904	protein domain specific binding

0.84	GO:0000164	protein phosphatase type 1 complex
0.72	GO:0072357	PTW/PP1 phosphatase complex
0.55	GO:0000784	nuclear chromosome, telomeric region
0.49	GO:0005913	cell-cell adherens junction
0.48	GO:0005654	nucleoplasm
0.47	GO:0005730	nucleolus
0.46	GO:0005741	mitochondrial outer membrane
0.45	GO:0005829	cytosol
0.42	GO:0043197	dendritic spine
0.40	GO:0043234	protein complex

sp|P62140|PP1B_HUMAN
Serine/threonine-protein phosphatase PP1-beta catalytic subunit
Search

PPP1CB

0.49	Serine/threonine-protein phosphatase

0.72	GO:0006470	protein dephosphorylation
0.51	GO:0042752	regulation of circadian rhythm
0.49	GO:0030155	regulation of cell adhesion
0.46	GO:0032922	circadian regulation of gene expression
0.46	GO:0009648	photoperiodism
0.46	GO:0060028	convergent extension involved in axis elongation
0.41	GO:0005977	glycogen metabolic process
0.41	GO:0001889	liver development
0.40	GO:0009605	response to external stimulus
0.39	GO:0051301	cell division

0.77	GO:0004722	protein serine/threonine phosphatase activity
0.57	GO:0050115	myosin-light-chain-phosphatase activity
0.54	GO:0046872	metal ion binding
0.48	GO:0019901	protein kinase binding
0.42	GO:0046982	protein heterodimerization activity

0.85	GO:0072357	PTW/PP1 phosphatase complex
0.84	GO:0000164	protein phosphatase type 1 complex
0.49	GO:0000784	nuclear chromosome, telomeric region
0.45	GO:0005829	cytosol
0.40	GO:0005886	plasma membrane
0.39	GO:0005730	nucleolus
0.39	GO:0005654	nucleoplasm
0.37	GO:0042587	glycogen granule
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome

0.57

EC:3.1.3.53

GO:0050115

sp|P62158|CALM_HUMAN
Calmodulin
Search

0.50	Calmodulin 1 (phosphorylase kinase, delta)

0.41	GO:0051343	positive regulation of cyclic-nucleotide phosphodiesterase activity
0.41	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity
0.40	GO:0005513	detection of calcium ion
0.40	GO:0032516	positive regulation of phosphoprotein phosphatase activity
0.40	GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
0.40	GO:0030819	positive regulation of cAMP biosynthetic process
0.39	GO:0055117	regulation of cardiac muscle contraction
0.39	GO:0002027	regulation of heart rate
0.39	GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity
0.38	GO:0043388	positive regulation of DNA binding

0.70	GO:0005509	calcium ion binding
0.41	GO:0031997	N-terminal myristoylation domain binding
0.40	GO:0031432	titin binding
0.40	GO:0008179	adenylate cyclase binding
0.40	GO:0072542	protein phosphatase activator activity
0.40	GO:0097718	disordered domain specific binding
0.39	GO:0044325	ion channel binding
0.39	GO:0019855	calcium channel inhibitor activity
0.38	GO:0019901	protein kinase binding
0.36	GO:0016301	kinase activity

0.40	GO:0034703	cation channel complex
0.39	GO:0000922	spindle pole
0.39	GO:0005876	spindle microtubule
0.39	GO:0030017	sarcomere
0.38	GO:0005813	centrosome
0.38	GO:0043209	myelin sheath
0.36	GO:0005887	integral component of plasma membrane
0.35	GO:1902494	catalytic complex
0.35	GO:0043234	protein complex
0.33	GO:0005829	cytosol

sp|P62166|NCS1_HUMAN
Neuronal calcium sensor 1
Search

NCS1

0.96	neuronal calcium sensor 1

0.43	GO:1905949	negative regulation of calcium ion import across plasma membrane
0.43	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.42	GO:0048731	system development
0.41	GO:0120035	regulation of plasma membrane bounded cell projection organization
0.41	GO:0010446	response to alkaline pH
0.41	GO:0051960	regulation of nervous system development
0.41	GO:0060284	regulation of cell development
0.41	GO:0048522	positive regulation of cellular process
0.41	GO:0070588	calcium ion transmembrane transport
0.40	GO:0007635	chemosensory behavior

0.70	GO:0005509	calcium ion binding
0.44	GO:0098744	1-phosphatidylinositol 4-kinase activator activity
0.42	GO:0005245	voltage-gated calcium channel activity
0.38	GO:0019901	protein kinase binding
0.36	GO:0000287	magnesium ion binding
0.35	GO:0008427	calcium-dependent protein kinase inhibitor activity
0.35	GO:0016301	kinase activity

0.52	GO:0036477	somatodendritic compartment
0.50	GO:0030424	axon
0.48	GO:0120038	plasma membrane bounded cell projection part
0.43	GO:0005794	Golgi apparatus
0.42	GO:0005886	plasma membrane
0.41	GO:0014069	postsynaptic density
0.40	GO:0048471	perinuclear region of cytoplasm
0.40	GO:0044297	cell body
0.40	GO:0031045	dense core granule
0.40	GO:0030054	cell junction

sp|P62191|PRS4_HUMAN
26S protease regulatory subunit 4
Search

PSMC1

0.85	26S proteasome regulatory subunit 4

0.81	GO:1901800	positive regulation of proteasomal protein catabolic process
0.70	GO:0030163	protein catabolic process
0.52	GO:0006508	proteolysis
0.50	GO:1901215	negative regulation of neuron death
0.48	GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly
0.47	GO:0034976	response to endoplasmic reticulum stress
0.46	GO:0010243	response to organonitrogen compound
0.44	GO:0043632	modification-dependent macromolecule catabolic process
0.39	GO:0044267	cellular protein metabolic process
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition

0.82	GO:0036402	proteasome-activating ATPase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0008233	peptidase activity
0.48	GO:0017025	TBP-class protein binding
0.33	GO:0003723	RNA binding
0.33	GO:0003887	DNA-directed DNA polymerase activity
0.32	GO:0003677	DNA binding

0.55	GO:1905369	endopeptidase complex
0.48	GO:0005737	cytoplasm
0.47	GO:0043234	protein complex
0.47	GO:0031981	nuclear lumen
0.30	GO:0016020	membrane

0.50

GO:0008233

sp|P62195|PRS8_HUMAN
26S protease regulatory subunit 8
Search

PSMC5

0.81	Testicular tissue protein Li 149

0.81	GO:1901800	positive regulation of proteasomal protein catabolic process
0.70	GO:0030163	protein catabolic process
0.53	GO:0006508	proteolysis
0.51	GO:0043632	modification-dependent macromolecule catabolic process
0.49	GO:0006357	regulation of transcription by RNA polymerase II
0.48	GO:0045892	negative regulation of transcription, DNA-templated
0.47	GO:2000144	positive regulation of DNA-templated transcription, initiation
0.46	GO:0034976	response to endoplasmic reticulum stress
0.45	GO:0010243	response to organonitrogen compound
0.43	GO:0044267	cellular protein metabolic process

0.82	GO:0036402	proteasome-activating ATPase activity
0.59	GO:0031531	thyrotropin-releasing hormone receptor binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0008134	transcription factor binding
0.49	GO:0008233	peptidase activity
0.36	GO:0003729	mRNA binding
0.35	GO:0043021	ribonucleoprotein complex binding

0.56	GO:1905369	endopeptidase complex
0.48	GO:0005737	cytoplasm
0.48	GO:0097708	intracellular vesicle
0.48	GO:0043234	protein complex
0.46	GO:0005634	nucleus
0.43	GO:0070013	intracellular organelle lumen
0.40	GO:0044446	intracellular organelle part
0.39	GO:0016234	inclusion body
0.38	GO:0098794	postsynapse
0.36	GO:0072562	blood microparticle

0.49

GO:0008233

sp|P62241|RS8_HUMAN
40S ribosomal protein S8
Search

RPS8

0.67	40S ribosomal protein S8

0.60	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.45	GO:0042274	ribosomal small subunit biogenesis
0.43	GO:0016072	rRNA metabolic process
0.37	GO:0043009	chordate embryonic development
0.36	GO:0051726	regulation of cell cycle
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane

0.64	GO:0003735	structural constituent of ribosome
0.33	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.61	GO:0005840	ribosome
0.48	GO:0044445	cytosolic part
0.43	GO:0005783	endoplasmic reticulum
0.42	GO:0044446	intracellular organelle part
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.34	GO:0005634	nucleus
0.33	GO:0043233	organelle lumen
0.30	GO:0031224	intrinsic component of membrane

sp|P62244|RS15A_HUMAN
40S ribosomal protein S15a
Search

RPS15A

0.74	Ribosomal protein S15a

0.59	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.46	GO:0045787	positive regulation of cell cycle
0.46	GO:0008284	positive regulation of cell proliferation
0.45	GO:0009615	response to virus
0.35	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.35	GO:0043009	chordate embryonic development
0.35	GO:0007420	brain development

0.63	GO:0003735	structural constituent of ribosome
0.34	GO:0003723	RNA binding
0.34	GO:0005515	protein binding
0.32	GO:0016787	hydrolase activity

0.60	GO:0005840	ribosome
0.46	GO:0044445	cytosolic part
0.41	GO:0044446	intracellular organelle part
0.40	GO:0005739	mitochondrion
0.38	GO:0031012	extracellular matrix
0.37	GO:0070062	extracellular exosome
0.34	GO:0043233	organelle lumen
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.32

GO:0016787

sp|P62249|RS16_HUMAN
40S ribosomal protein S16
Search

RPS16

0.64	Ribosomal protein S16

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.50	GO:1990830	cellular response to leukemia inhibitory factor
0.49	GO:0042274	ribosomal small subunit biogenesis
0.47	GO:0016072	rRNA metabolic process
0.39	GO:0097421	liver regeneration
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane

0.64	GO:0003735	structural constituent of ribosome
0.43	GO:0003723	RNA binding
0.33	GO:0005515	protein binding
0.32	GO:0016787	hydrolase activity

0.61	GO:0005840	ribosome
0.49	GO:0044445	cytosolic part
0.42	GO:0044446	intracellular organelle part
0.36	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.34	GO:0005791	rough endoplasmic reticulum
0.34	GO:0098562	cytoplasmic side of membrane
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0098588	bounding membrane of organelle

0.32

GO:0016787

sp|P62253|UB2G1_HUMAN
Ubiquitin-conjugating enzyme E2 G1
Search

UBE2G1

0.88	Ubiquitin-conjugating enzyme E2G 1

0.51	GO:0000209	protein polyubiquitination
0.47	GO:0044257	cellular protein catabolic process
0.44	GO:0043632	modification-dependent macromolecule catabolic process
0.40	GO:0006508	proteolysis

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.50	GO:0031625	ubiquitin protein ligase binding
0.47	GO:0004842	ubiquitin-protein transferase activity
0.45	GO:0061659	ubiquitin-like protein ligase activity
0.44	GO:0061650	ubiquitin-like protein conjugating enzyme activity

0.36

GO:0005737

cytoplasm

0.47

KEGG:R03876

GO:0004842

sp|P62256|UBE2H_HUMAN
Ubiquitin-conjugating enzyme E2 H
Search

UBE2H

0.91	Ubiquitin-conjugating enzyme E2H

0.47	GO:0006511	ubiquitin-dependent protein catabolic process
0.47	GO:0016567	protein ubiquitination
0.45	GO:0010498	proteasomal protein catabolic process

0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0061631	ubiquitin conjugating enzyme activity
0.47	GO:0031625	ubiquitin protein ligase binding
0.46	GO:0061630	ubiquitin protein ligase activity

0.37

GO:0005737

cytoplasm

sp|P62258|1433E_HUMAN
14-3-3 protein epsilon
Search

YWHAE

0.91	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon

0.55	GO:1905912	regulation of calcium ion export across plasma membrane
0.54	GO:1902309	negative regulation of peptidyl-serine dephosphorylation
0.52	GO:0046827	positive regulation of protein export from nucleus
0.52	GO:0060306	regulation of membrane repolarization
0.52	GO:1901020	negative regulation of calcium ion transmembrane transporter activity
0.51	GO:1901016	regulation of potassium ion transmembrane transporter activity
0.50	GO:0034605	cellular response to heat
0.50	GO:0051480	regulation of cytosolic calcium ion concentration
0.50	GO:0021766	hippocampus development
0.49	GO:0000165	MAPK cascade

0.75	GO:0019904	protein domain specific binding
0.53	GO:0050815	phosphoserine residue binding
0.52	GO:0015459	potassium channel regulator activity
0.52	GO:0097110	scaffold protein binding
0.51	GO:0005246	calcium channel regulator activity
0.51	GO:0044325	ion channel binding
0.51	GO:0042826	histone deacetylase binding
0.50	GO:0045296	cadherin binding
0.49	GO:0031625	ubiquitin protein ligase binding
0.47	GO:0046982	protein heterodimerization activity

0.42	GO:0005634	nucleus
0.42	GO:0090724	central region of growth cone
0.41	GO:0042470	melanosome
0.41	GO:0005739	mitochondrion
0.40	GO:0005886	plasma membrane
0.40	GO:0005871	kinesin complex
0.39	GO:0030424	axon
0.37	GO:0005829	cytosol
0.37	GO:0005925	focal adhesion
0.37	GO:0070062	extracellular exosome

sp|P62263|RS14_HUMAN
40S ribosomal protein S14
Search

RPS14

0.62	Ribosomal protein S14

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.54	GO:0030218	erythrocyte differentiation
0.53	GO:0009059	macromolecule biosynthetic process
0.52	GO:0000028	ribosomal small subunit assembly
0.47	GO:0000122	negative regulation of transcription by RNA polymerase II
0.45	GO:0006417	regulation of translation
0.44	GO:0061515	myeloid cell development
0.43	GO:0071695	anatomical structure maturation

0.64	GO:0003735	structural constituent of ribosome
0.51	GO:0048027	mRNA 5'-UTR binding
0.49	GO:0045182	translation regulator activity
0.44	GO:0070181	small ribosomal subunit rRNA binding
0.39	GO:0042289	MHC class II protein binding
0.34	GO:0004683	calmodulin-dependent protein kinase activity
0.34	GO:0005516	calmodulin binding
0.34	GO:0008146	sulfotransferase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding

0.61	GO:0005840	ribosome
0.47	GO:0044445	cytosolic part
0.46	GO:0005730	nucleolus
0.41	GO:0005739	mitochondrion
0.36	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.33	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:2.7.11.17

GO:0004683

sp|P62266|RS23_HUMAN
40S ribosomal protein S23
Search

RPS23

0.72	Ribosomal protein S23

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0034063	stress granule assembly
0.53	GO:0009059	macromolecule biosynthetic process
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.34	GO:0006417	regulation of translation
0.33	GO:0016072	rRNA metabolic process

0.64	GO:0003735	structural constituent of ribosome
0.34	GO:0045182	translation regulator activity
0.34	GO:0005515	protein binding
0.33	GO:0003723	RNA binding
0.32	GO:0046872	metal ion binding

0.69	GO:0015935	small ribosomal subunit
0.54	GO:0042788	polysomal ribosome
0.53	GO:0022626	cytosolic ribosome
0.47	GO:0005783	endoplasmic reticulum
0.34	GO:0098562	cytoplasmic side of membrane
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0005654	nucleoplasm
0.33	GO:0031984	organelle subcompartment

sp|P62269|RS18_HUMAN
40S ribosomal protein S18
Search

RPS18

0.43	Ribosomal protein S18

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.43	GO:0042254	ribosome biogenesis
0.41	GO:0051726	regulation of cell cycle
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0043413	macromolecule glycosylation
0.34	GO:0009100	glycoprotein metabolic process

0.64	GO:0003735	structural constituent of ribosome
0.59	GO:0003723	RNA binding
0.35	GO:0005515	protein binding
0.34	GO:0008378	galactosyltransferase activity
0.33	GO:0046873	metal ion transmembrane transporter activity
0.32	GO:0016491	oxidoreductase activity

0.61	GO:0005840	ribosome
0.46	GO:0005829	cytosol
0.41	GO:0044446	intracellular organelle part
0.37	GO:0005634	nucleus
0.36	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.34	GO:0005791	rough endoplasmic reticulum
0.34	GO:0098562	cytoplasmic side of membrane
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network

0.34

GO:0008378

sp|P62273|RS29_HUMAN
40S ribosomal protein S29
Search

RPS29

0.85	Ribosomal protein S29

0.57	GO:0043043	peptide biosynthetic process
0.53	GO:0044267	cellular protein metabolic process
0.52	GO:0010467	gene expression
0.51	GO:0009059	macromolecule biosynthetic process
0.46	GO:0060218	hematopoietic stem cell differentiation
0.46	GO:0048821	erythrocyte development
0.45	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator
0.45	GO:0001570	vasculogenesis
0.44	GO:0001525	angiogenesis
0.43	GO:0043009	chordate embryonic development

0.61	GO:0003735	structural constituent of ribosome
0.44	GO:0008270	zinc ion binding
0.39	GO:0003723	RNA binding
0.32	GO:0016787	hydrolase activity

0.59	GO:0005840	ribosome
0.49	GO:0005844	polysome
0.48	GO:0044445	cytosolic part
0.44	GO:0098556	cytoplasmic side of rough endoplasmic reticulum membrane
0.37	GO:0005925	focal adhesion
0.37	GO:0070062	extracellular exosome
0.34	GO:0005654	nucleoplasm

0.32

GO:0016787

sp|P62277|RS13_HUMAN
40S ribosomal protein S13
Search

RPS13

0.71	Ribosomal protein S13

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.49	GO:0033119	negative regulation of RNA splicing
0.37	GO:0048015	phosphatidylinositol-mediated signaling
0.37	GO:0046854	phosphatidylinositol phosphorylation
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription

0.64	GO:0003735	structural constituent of ribosome
0.47	GO:0048027	mRNA 5'-UTR binding
0.46	GO:0070181	small ribosomal subunit rRNA binding
0.36	GO:1990932	5.8S rRNA binding
0.35	GO:0035091	phosphatidylinositol binding
0.35	GO:0016301	kinase activity
0.34	GO:0005515	protein binding
0.32	GO:0016787	hydrolase activity

0.61	GO:0005840	ribosome
0.47	GO:0005730	nucleolus
0.47	GO:0044445	cytosolic part
0.36	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.33	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

0.32

GO:0016787

sp|P62280|RS11_HUMAN
40S ribosomal protein S11
Search

RPS11

0.60	Ribosomal protein S11

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.35	GO:0010469	regulation of receptor activity
0.35	GO:0001649	osteoblast differentiation
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.33	GO:0016072	rRNA metabolic process

0.64	GO:0003735	structural constituent of ribosome
0.37	GO:0019843	rRNA binding
0.36	GO:0005125	cytokine activity
0.33	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

0.61	GO:0005840	ribosome
0.51	GO:0044445	cytosolic part
0.44	GO:0044446	intracellular organelle part
0.36	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.34	GO:0031974	membrane-enclosed lumen
0.34	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.33

EC:1.2.1

GO:0016620

sp|P62304|RUXE_HUMAN
Small nuclear ribonucleoprotein E
Search

SNRPE

0.84	Small nuclear ribonucleoprotein polypeptide E

0.74	GO:0000398	mRNA splicing, via spliceosome
0.46	GO:0022618	ribonucleoprotein complex assembly
0.44	GO:0042633	hair cycle
0.36	GO:0008334	histone mRNA metabolic process
0.35	GO:0006369	termination of RNA polymerase II transcription
0.34	GO:0051170	nuclear import

0.37	GO:0003723	RNA binding
0.36	GO:1990446	U1 snRNP binding
0.33	GO:0005515	protein binding

0.75	GO:0005681	spliceosomal complex
0.63	GO:0019013	viral nucleocapsid
0.51	GO:0005687	U4 snRNP
0.49	GO:0005682	U5 snRNP
0.49	GO:0005685	U1 snRNP
0.49	GO:0005686	U2 snRNP
0.48	GO:0046540	U4/U6 x U5 tri-snRNP complex
0.46	GO:0034709	methylosome
0.46	GO:0034715	pICln-Sm protein complex
0.46	GO:0034719	SMN-Sm protein complex

sp|P62306|RUXF_HUMAN
Small nuclear ribonucleoprotein F
Search

SNRPF

0.90	Small nuclear ribonucleoprotein polypeptide F

0.80	GO:0000387	spliceosomal snRNP assembly
0.36	GO:0043606	formamide metabolic process
0.36	GO:0006548	histidine catabolic process
0.35	GO:0006536	glutamate metabolic process
0.35	GO:0008334	histone mRNA metabolic process
0.35	GO:0006369	termination of RNA polymerase II transcription
0.34	GO:0008217	regulation of blood pressure
0.34	GO:0097746	regulation of blood vessel diameter
0.34	GO:0051170	nuclear import
0.33	GO:0007186	G-protein coupled receptor signaling pathway

0.55	GO:0003723	RNA binding
0.35	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
0.35	GO:0001604	urotensin II receptor activity
0.33	GO:0005515	protein binding

0.79	GO:0005732	small nucleolar ribonucleoprotein complex
0.76	GO:0005681	spliceosomal complex
0.60	GO:0019013	viral nucleocapsid
0.54	GO:0005683	U7 snRNP
0.54	GO:0005685	U1 snRNP
0.53	GO:0005687	U4 snRNP
0.53	GO:0034709	methylosome
0.53	GO:0034715	pICln-Sm protein complex
0.53	GO:0034719	SMN-Sm protein complex
0.45	GO:0005829	cytosol

0.35

EC:3.5.2

GO:0016812

sp|P62308|RUXG_HUMAN
Small nuclear ribonucleoprotein G
Search

SNRPG

0.88	Small nuclear ribonucleoprotein polypeptide G

0.80	GO:0000387	spliceosomal snRNP assembly
0.35	GO:0008334	histone mRNA metabolic process
0.35	GO:0006369	termination of RNA polymerase II transcription
0.34	GO:0000245	spliceosomal complex assembly
0.34	GO:0051170	nuclear import
0.33	GO:0055114	oxidation-reduction process

0.41	GO:0003723	RNA binding
0.35	GO:0004148	dihydrolipoyl dehydrogenase activity
0.35	GO:1990446	U1 snRNP binding
0.33	GO:0070279	vitamin B6 binding
0.33	GO:0005515	protein binding
0.33	GO:0050662	coenzyme binding
0.32	GO:0043168	anion binding

0.76	GO:0005681	spliceosomal complex
0.58	GO:0019013	viral nucleocapsid
0.51	GO:0005687	U4 snRNP
0.51	GO:0034719	SMN-Sm protein complex
0.51	GO:0043186	P granule
0.50	GO:0005682	U5 snRNP
0.49	GO:0005686	U2 snRNP
0.49	GO:0005685	U1 snRNP
0.48	GO:0097526	spliceosomal tri-snRNP complex
0.42	GO:1902494	catalytic complex

0.35

EC:1.8.1.4

GO:0004148

sp|P62310|LSM3_HUMAN
U6 snRNA-associated Sm-like protein LSm3
Search

LSM3

0.92	LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated

0.78	GO:0000956	nuclear-transcribed mRNA catabolic process
0.75	GO:0000398	mRNA splicing, via spliceosome
0.49	GO:0033962	cytoplasmic mRNA processing body assembly
0.33	GO:0007264	small GTPase mediated signal transduction
0.33	GO:0065009	regulation of molecular function

0.40	GO:0003723	RNA binding
0.34	GO:0005515	protein binding
0.33	GO:0098772	molecular function regulator

0.56	GO:0030529	intracellular ribonucleoprotein complex
0.49	GO:1990726	Lsm1-7-Pat1 complex
0.46	GO:0044428	nuclear part
0.44	GO:1902494	catalytic complex
0.40	GO:0043232	intracellular non-membrane-bounded organelle
0.38	GO:0044444	cytoplasmic part
0.38	GO:0019013	viral nucleocapsid
0.33	GO:0031974	membrane-enclosed lumen

sp|P62312|LSM6_HUMAN
U6 snRNA-associated Sm-like protein LSm6
Search

LSM6

0.87	LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated

0.75	GO:0000398	mRNA splicing, via spliceosome
0.46	GO:0030490	maturation of SSU-rRNA
0.35	GO:0007034	vacuolar transport
0.35	GO:0006402	mRNA catabolic process
0.34	GO:0008033	tRNA processing
0.32	GO:0055085	transmembrane transport

0.58	GO:0003723	RNA binding
0.34	GO:0005515	protein binding
0.32	GO:0005215	transporter activity

0.79	GO:0005732	small nucleolar ribonucleoprotein complex
0.74	GO:0005681	spliceosomal complex
0.48	GO:0005688	U6 snRNP
0.47	GO:0000932	P-body
0.47	GO:0046540	U4/U6 x U5 tri-snRNP complex
0.45	GO:0005730	nucleolus
0.42	GO:0019013	viral nucleocapsid
0.36	GO:0070062	extracellular exosome
0.33	GO:0005654	nucleoplasm
0.33	GO:0005829	cytosol

sp|P62314|SMD1_HUMAN
Small nuclear ribonucleoprotein Sm D1
Search

SNRPD1

0.84	Small nuclear ribonucleoprotein D1 polypeptide

0.81	GO:0000387	spliceosomal snRNP assembly
0.47	GO:0000245	spliceosomal complex assembly
0.43	GO:0007507	heart development
0.35	GO:1901800	positive regulation of proteasomal protein catabolic process
0.34	GO:0030163	protein catabolic process
0.34	GO:0001756	somitogenesis
0.34	GO:0001841	neural tube formation
0.34	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.34	GO:0045807	positive regulation of endocytosis
0.34	GO:0007368	determination of left/right symmetry

0.40	GO:0003723	RNA binding
0.39	GO:1990446	U1 snRNP binding
0.35	GO:0036402	proteasome-activating ATPase activity
0.33	GO:0003839	gamma-glutamylcyclotransferase activity
0.33	GO:0004842	ubiquitin-protein transferase activity
0.33	GO:0005515	protein binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0008270	zinc ion binding

0.60	GO:0019013	viral nucleocapsid
0.60	GO:0030529	intracellular ribonucleoprotein complex
0.55	GO:0034715	pICln-Sm protein complex
0.55	GO:0034719	SMN-Sm protein complex
0.51	GO:0034709	methylosome
0.46	GO:0044428	nuclear part
0.44	GO:0005829	cytosol
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0005813	centrosome
0.33	GO:0031410	cytoplasmic vesicle

0.33	EC:2.3.2.4	GO:0003839
0.33	KEGG:R03876	GO:0004842

sp|P62316|SMD2_HUMAN
Small nuclear ribonucleoprotein Sm D2
Search

SNRPD2

0.87	Small nuclear ribonucleoprotein D2 polypeptide

0.74	GO:0008380	RNA splicing
0.47	GO:0022618	ribonucleoprotein complex assembly
0.46	GO:0006397	mRNA processing
0.34	GO:0051170	nuclear import
0.33	GO:2001141	regulation of RNA biosynthetic process
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression

0.38	GO:1990446	U1 snRNP binding
0.34	GO:0043565	sequence-specific DNA binding
0.34	GO:0003700	DNA binding transcription factor activity
0.33	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.78	GO:0030532	small nuclear ribonucleoprotein complex
0.61	GO:0019013	viral nucleocapsid
0.50	GO:0071013	catalytic step 2 spliceosome
0.48	GO:0071011	precatalytic spliceosome
0.47	GO:0034709	methylosome
0.47	GO:0034715	pICln-Sm protein complex
0.47	GO:0034719	SMN-Sm protein complex
0.46	GO:0005689	U12-type spliceosomal complex
0.44	GO:0005684	U2-type spliceosomal complex
0.41	GO:0005829	cytosol

sp|P62318|SMD3_HUMAN
Small nuclear ribonucleoprotein Sm D3
Search

SNRPD3

0.86	Small nuclear ribonucleoprotein D3 polypeptide

0.80	GO:0000387	spliceosomal snRNP assembly
0.48	GO:0008213	protein alkylation
0.46	GO:0000245	spliceosomal complex assembly
0.45	GO:0043414	macromolecule methylation
0.35	GO:0008334	histone mRNA metabolic process
0.35	GO:0006369	termination of RNA polymerase II transcription
0.34	GO:0051170	nuclear import

0.56	GO:0071209	U7 snRNA binding
0.55	GO:0071208	histone pre-mRNA DCP binding
0.55	GO:0030620	U2 snRNA binding
0.54	GO:0070034	telomerase RNA binding
0.47	GO:0019899	enzyme binding
0.39	GO:1990446	U1 snRNP binding

0.76	GO:0005681	spliceosomal complex
0.62	GO:0019013	viral nucleocapsid
0.56	GO:0005687	U4 snRNP
0.56	GO:0034715	pICln-Sm protein complex
0.56	GO:0034719	SMN-Sm protein complex
0.55	GO:0005683	U7 snRNP
0.54	GO:0034709	methylosome
0.54	GO:0005697	telomerase holoenzyme complex
0.53	GO:0005685	U1 snRNP
0.50	GO:0016604	nuclear body

sp|P62324|BTG1_HUMAN
Protein BTG1
Search

BTG1

0.96	B-cell translocation protein 1, anti-proliferative

0.79	GO:0008285	negative regulation of cell proliferation
0.57	GO:2000271	positive regulation of fibroblast apoptotic process
0.57	GO:0045603	positive regulation of endothelial cell differentiation
0.55	GO:0045663	positive regulation of myoblast differentiation
0.54	GO:0045766	positive regulation of angiogenesis
0.48	GO:0021542	dentate gyrus development
0.48	GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
0.47	GO:0035914	skeletal muscle cell differentiation
0.47	GO:0008213	protein alkylation
0.47	GO:0008306	associative learning

0.48	GO:0019899	enzyme binding
0.37	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.34	GO:0003712	transcription cofactor activity

0.44	GO:0005634	nucleus
0.39	GO:0005737	cytoplasm
0.35	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

sp|P62328|TYB4_HUMAN
Thymosin beta-4
Search

0.97	Thymosin beta 4 X-linked

0.75	GO:0007015	actin filament organization
0.49	GO:1905271	regulation of proton-transporting ATP synthase activity, rotational mechanism
0.48	GO:0042989	sequestering of actin monomers
0.47	GO:0007253	cytoplasmic sequestering of NF-kappaB
0.47	GO:2000483	negative regulation of interleukin-8 secretion
0.47	GO:2001171	positive regulation of ATP biosynthetic process
0.47	GO:1901223	negative regulation of NIK/NF-kappaB signaling
0.47	GO:2001028	positive regulation of endothelial cell chemotaxis
0.46	GO:1903026	negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding
0.46	GO:0043536	positive regulation of blood vessel endothelial cell migration

0.85	GO:0003785	actin monomer binding
0.41	GO:0019899	enzyme binding
0.36	GO:0003727	single-stranded RNA binding
0.35	GO:0004888	transmembrane signaling receptor activity

0.43	GO:0005856	cytoskeleton
0.42	GO:0005829	cytosol
0.41	GO:0005576	extracellular region
0.40	GO:0005634	nucleus
0.35	GO:0031093	platelet alpha granule lumen
0.30	GO:0016020	membrane

sp|P62330|ARF6_HUMAN
ADP-ribosylation factor 6
Search

ARF6

0.79	ADP-ribosylation factor 6

0.56	GO:0035020	regulation of Rac protein signal transduction
0.56	GO:0033028	myeloid cell apoptotic process
0.56	GO:0036010	protein localization to endosome
0.56	GO:0001889	liver development
0.55	GO:0097178	ruffle assembly
0.55	GO:0097284	hepatocyte apoptotic process
0.55	GO:0051489	regulation of filopodium assembly
0.54	GO:0034394	protein localization to cell surface
0.54	GO:0032456	endocytic recycling
0.53	GO:0060998	regulation of dendritic spine development

0.66	GO:0005525	GTP binding
0.56	GO:0031996	thioesterase binding
0.53	GO:0047485	protein N-terminus binding
0.36	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity
0.35	GO:0031681	G-protein beta-subunit binding
0.34	GO:0003924	GTPase activity

0.56	GO:0031527	filopodium membrane
0.56	GO:0090543	Flemming body
0.55	GO:0032154	cleavage furrow
0.55	GO:0055038	recycling endosome membrane
0.53	GO:0001726	ruffle
0.53	GO:0030139	endocytic vesicle
0.51	GO:0043209	myelin sheath
0.50	GO:0005938	cell cortex
0.39	GO:0005769	early endosome
0.38	GO:0005829	cytosol

0.36

EC:2.4.2.31

GO:0003956

sp|P62333|PRS10_HUMAN
26S protease regulatory subunit 10B
Search

PSMC6

0.85	Proteasome (Prosome, macropain) 26S subunit, ATPase, 6

0.70	GO:1901800	positive regulation of proteasomal protein catabolic process
0.67	GO:0030163	protein catabolic process
0.53	GO:0006508	proteolysis
0.47	GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly
0.46	GO:0034976	response to endoplasmic reticulum stress
0.45	GO:0010243	response to organonitrogen compound
0.43	GO:0043632	modification-dependent macromolecule catabolic process
0.41	GO:0090261	positive regulation of inclusion body assembly
0.38	GO:0044267	cellular protein metabolic process
0.36	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition

0.71	GO:0036402	proteasome-activating ATPase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0008233	peptidase activity
0.46	GO:0017025	TBP-class protein binding
0.37	GO:0042802	identical protein binding
0.35	GO:0030674	protein binding, bridging

0.55	GO:1905369	endopeptidase complex
0.47	GO:0043234	protein complex
0.47	GO:0005737	cytoplasm
0.42	GO:0031981	nuclear lumen
0.40	GO:0016234	inclusion body
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.52

GO:0008233

sp|P62341|SELT_HUMAN
Selenoprotein T
Search

SELENOT

0.96	Selenoprotein T

0.61	GO:0035773	insulin secretion involved in cellular response to glucose stimulus
0.57	GO:0031016	pancreas development
0.49	GO:0045454	cell redox homeostasis
0.45	GO:0060124	positive regulation of growth hormone secretion
0.42	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.41	GO:0098869	cellular oxidant detoxification
0.36	GO:0055114	oxidation-reduction process
0.35	GO:0001514	selenocysteine incorporation
0.32	GO:0006413	translational initiation

0.43	GO:0004791	thioredoxin-disulfide reductase activity
0.36	GO:0008430	selenium binding
0.33	GO:0005201	extracellular matrix structural constituent
0.32	GO:0003743	translation initiation factor activity

0.51	GO:0005783	endoplasmic reticulum
0.41	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.40	GO:0031984	organelle subcompartment
0.33	GO:0005604	basement membrane
0.33	GO:0005581	collagen trimer
0.30	GO:0016021	integral component of membrane

0.43	EC:1.8.1.9	GO:0004791
0.43	KEGG:R02016	GO:0004791

sp|P62380|TBPL1_HUMAN
TATA box-binding protein-like protein 1
Search

TBPL1

0.96	TATA-box binding protein like 1

0.69	GO:0006352	DNA-templated transcription, initiation
0.57	GO:0001675	acrosome assembly
0.56	GO:0007289	spermatid nucleus differentiation
0.53	GO:0006366	transcription by RNA polymerase II
0.51	GO:0006235	dTTP biosynthetic process
0.51	GO:0045944	positive regulation of transcription by RNA polymerase II
0.41	GO:0009792	embryo development ending in birth or egg hatching
0.34	GO:0006413	translational initiation
0.32	GO:0055114	oxidation-reduction process

0.55	GO:0003677	DNA binding
0.54	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.51	GO:0001067	regulatory region nucleic acid binding
0.35	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.34	GO:0005515	protein binding
0.34	GO:0003713	transcription coactivator activity
0.34	GO:0003743	translation initiation factor activity
0.32	GO:0008270	zinc ion binding

0.54	GO:0005672	transcription factor TFIIA complex
0.39	GO:0005737	cytoplasm
0.33	GO:0031514	motile cilium

0.35

EC:1.3.1.74

GO:0032440

sp|P62424|RL7A_HUMAN
60S ribosomal protein L7a
Search

RPL7A

0.82	Ribosomal protein L7A, pseudogene 3

0.66	GO:0042254	ribosome biogenesis
0.45	GO:0016072	rRNA metabolic process
0.43	GO:0034470	ncRNA processing
0.42	GO:0043043	peptide biosynthetic process
0.40	GO:0044267	cellular protein metabolic process
0.39	GO:0009059	macromolecule biosynthetic process
0.36	GO:1904401	cellular response to Thyroid stimulating hormone
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription

0.45	GO:0045296	cadherin binding
0.41	GO:0003723	RNA binding
0.33	GO:0003735	structural constituent of ribosome

0.61	GO:0030529	intracellular ribonucleoprotein complex
0.52	GO:0043232	intracellular non-membrane-bounded organelle
0.49	GO:0044444	cytoplasmic part
0.41	GO:0044446	intracellular organelle part
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.34	GO:0031974	membrane-enclosed lumen
0.34	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|P62487|RPB7_HUMAN
DNA-directed RNA polymerase II subunit RPB7
Search

POLR2G

0.86	DNA-directed RNA polymerase II polypeptide G

0.58	GO:0006351	transcription, DNA-templated
0.50	GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
0.49	GO:0000291	nuclear-transcribed mRNA catabolic process, exonucleolytic
0.48	GO:0045948	positive regulation of translational initiation
0.36	GO:0006915	apoptotic process
0.36	GO:0051090	regulation of DNA binding transcription factor activity
0.35	GO:0035019	somatic stem cell population maintenance
0.35	GO:0060964	regulation of gene silencing by miRNA
0.34	GO:0008543	fibroblast growth factor receptor signaling pathway
0.34	GO:0016073	snRNA metabolic process

0.70	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.51	GO:0003676	nucleic acid binding
0.48	GO:0031369	translation initiation factor binding
0.35	GO:0046982	protein heterodimerization activity

0.55	GO:0005665	DNA-directed RNA polymerase II, core complex
0.47	GO:0000932	P-body
0.36	GO:0046695	SLIK (SAGA-like) complex
0.36	GO:0000124	SAGA complex
0.36	GO:0005669	transcription factor TFIID complex
0.30	GO:0031224	intrinsic component of membrane

0.70

GO:0003899

sp|P62491|RB11A_HUMAN
Ras-related protein Rab-11A
Search

RAB11A

0.88	Novel protein similar to vertebrate Ras family

0.66	GO:0032402	melanosome transport
0.57	GO:0006887	exocytosis
0.57	GO:0010796	regulation of multivesicular body size
0.57	GO:0060627	regulation of vesicle-mediated transport
0.57	GO:0097734	extracellular exosome biogenesis
0.56	GO:0030953	astral microtubule organization
0.56	GO:0036258	multivesicular body assembly
0.56	GO:0045773	positive regulation of axon extension
0.55	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle
0.54	GO:0007080	mitotic metaphase plate congression

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.62	GO:0031489	myosin V binding
0.49	GO:0008017	microtubule binding
0.49	GO:0019003	GDP binding
0.47	GO:0045296	cadherin binding
0.34	GO:0019905	syntaxin binding
0.34	GO:0019904	protein domain specific binding
0.33	GO:0008270	zinc ion binding
0.33	GO:0016874	ligase activity

0.62	GO:0055037	recycling endosome
0.60	GO:0045335	phagocytic vesicle
0.55	GO:0005771	multivesicular body
0.55	GO:0032154	cleavage furrow
0.54	GO:0005828	kinetochore microtubule
0.53	GO:0070062	extracellular exosome
0.52	GO:0030424	axon
0.52	GO:0048471	perinuclear region of cytoplasm
0.52	GO:0005802	trans-Golgi network
0.52	GO:0000922	spindle pole

0.33

GO:0016874

sp|P62495|ERF1_HUMAN
Eukaryotic peptide chain release factor subunit 1
Search

ETF1

0.80	Eukaryotic peptide chain release factor subunit 1

0.72	GO:0006415	translational termination
0.47	GO:0008213	protein alkylation
0.45	GO:0043414	macromolecule methylation
0.43	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.42	GO:0007420	brain development
0.34	GO:0006449	regulation of translational termination
0.33	GO:0016032	viral process

0.73	GO:0008079	translation termination factor activity
0.55	GO:1990825	sequence-specific mRNA binding
0.34	GO:0043022	ribosome binding
0.33	GO:0005515	protein binding

0.48	GO:0005737	cytoplasm
0.34	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|P62502|LCN6_HUMAN
Epididymal-specific lipocalin-6
Search

LCN6

0.97	Epididymal-specific lipocalin-6

0.43

GO:0007338

single fertilization

0.51

GO:0036094

small molecule binding

0.39

GO:0005576

extracellular region

sp|P62508|ERR3_HUMAN
Estrogen-related receptor gamma
Search

ESRRG

0.97	Estrogen-related nuclear receptor gamma variant 1

0.76	GO:0043401	steroid hormone mediated signaling pathway
0.61	GO:0048384	retinoic acid receptor signaling pathway
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:2001141	regulation of RNA biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.48	GO:0051254	positive regulation of RNA metabolic process
0.48	GO:0010557	positive regulation of macromolecule biosynthetic process
0.48	GO:0031328	positive regulation of cellular biosynthetic process
0.43	GO:0071599	otic vesicle development

0.78	GO:0005496	steroid binding
0.77	GO:0003707	steroid hormone receptor activity
0.62	GO:0043565	sequence-specific DNA binding
0.62	GO:0003708	retinoic acid receptor activity
0.61	GO:0008270	zinc ion binding
0.51	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.50	GO:0001012	RNA polymerase II regulatory region DNA binding
0.48	GO:0003690	double-stranded DNA binding
0.38	GO:0050682	AF-2 domain binding
0.34	GO:0005516	calmodulin binding

0.60	GO:0005634	nucleus
0.33	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part

sp|P62633|CNBP_HUMAN
Cellular nucleic acid-binding protein
Search

CNBP

0.79	CCHC-type zinc finger, nucleic acid binding protein b

0.52	GO:0008284	positive regulation of cell proliferation
0.51	GO:0045944	positive regulation of transcription by RNA polymerase II
0.49	GO:0000122	negative regulation of transcription by RNA polymerase II
0.39	GO:0014036	neural crest cell fate specification
0.38	GO:0048703	embryonic viscerocranium morphogenesis
0.37	GO:0051216	cartilage development
0.37	GO:0060322	head development
0.36	GO:0006351	transcription, DNA-templated
0.35	GO:0006695	cholesterol biosynthetic process
0.33	GO:0000350	generation of catalytic spliceosome for second transesterification step

0.63	GO:0008270	zinc ion binding
0.51	GO:0003676	nucleic acid binding
0.51	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.37	GO:0003682	chromatin binding
0.33	GO:0005515	protein binding
0.33	GO:0016874	ligase activity

0.48	GO:0005783	endoplasmic reticulum
0.47	GO:0005829	cytosol
0.44	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.33

GO:0016874

sp|P62684|GA113_HUMAN
Endogenous retrovirus group K member 113 Gag polyprotein
Search

0.20	Endogenous retrovirus group K member 9 Gag polyprotein

0.63	GO:0016032	viral process
0.43	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.43	GO:0006278	RNA-dependent DNA biosynthetic process
0.41	GO:0006508	proteolysis
0.40	GO:0015074	DNA integration
0.37	GO:0051806	entry into cell of other organism involved in symbiotic interaction
0.37	GO:0044409	entry into host
0.36	GO:0006310	DNA recombination

0.63	GO:0008270	zinc ion binding
0.61	GO:0005198	structural molecule activity
0.51	GO:0003676	nucleic acid binding
0.45	GO:0070001	aspartic-type peptidase activity
0.44	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.43	GO:0003964	RNA-directed DNA polymerase activity
0.43	GO:0004175	endopeptidase activity
0.39	GO:0003887	DNA-directed DNA polymerase activity
0.37	GO:0004170	dUTP diphosphatase activity
0.33	GO:0005515	protein binding

0.66	GO:0019028	viral capsid
0.46	GO:0005886	plasma membrane
0.37	GO:0036338	viral membrane
0.35	GO:0030430	host cell cytoplasm
0.34	GO:0042025	host cell nucleus
0.30	GO:0016021	integral component of membrane

0.44	EC:3.1.26.4	GO:0004523
0.37	KEGG:R02100	GO:0004170

sp|P62699|YPEL5_HUMAN
Protein yippee-like 5
Search

0.35	GO:0043312	neutrophil degranulation
0.33	GO:0098655	cation transmembrane transport

0.54	GO:0046872	metal ion binding
0.33	GO:0008324	cation transmembrane transporter activity

0.35	GO:1904724	tertiary granule lumen
0.35	GO:1904813	ficolin-1-rich granule lumen
0.33	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

sp|P62701|RS4X_HUMAN
40S ribosomal protein S4, X isoform
Search

RPS4X

0.67	Ribosomal protein S4, X-linked X isoform variant (Fragment)

0.60	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.49	GO:0008284	positive regulation of cell proliferation
0.48	GO:0045727	positive regulation of translation
0.46	GO:0007275	multicellular organism development
0.38	GO:0060322	head development
0.38	GO:0045471	response to ethanol
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

0.64	GO:0003735	structural constituent of ribosome
0.63	GO:0019843	rRNA binding
0.33	GO:0005515	protein binding

0.61	GO:0005840	ribosome
0.50	GO:0044445	cytosolic part
0.50	GO:0005844	polysome
0.49	GO:0036464	cytoplasmic ribonucleoprotein granule
0.43	GO:0044446	intracellular organelle part
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.35	GO:0031012	extracellular matrix
0.33	GO:0043233	organelle lumen
0.33	GO:0005634	nucleus

sp|P62714|PP2AB_HUMAN
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform
Search

0.47	Serine/threonine-protein phosphatase

0.72	GO:0006470	protein dephosphorylation
0.52	GO:0010719	negative regulation of epithelial to mesenchymal transition
0.52	GO:0008637	apoptotic mitochondrial changes
0.51	GO:0042542	response to hydrogen peroxide
0.50	GO:0007498	mesoderm development
0.49	GO:0034976	response to endoplasmic reticulum stress
0.48	GO:0071902	positive regulation of protein serine/threonine kinase activity
0.48	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.47	GO:0046677	response to antibiotic
0.42	GO:1904528	positive regulation of microtubule binding

0.72	GO:0004721	phosphoprotein phosphatase activity
0.52	GO:0050811	GABA receptor binding
0.51	GO:0008022	protein C-terminus binding
0.48	GO:0046982	protein heterodimerization activity
0.37	GO:0046872	metal ion binding
0.35	GO:1990405	protein antigen binding
0.35	GO:0031698	beta-2 adrenergic receptor binding
0.35	GO:0048156	tau protein binding
0.35	GO:0043422	protein kinase B binding
0.35	GO:0051721	protein phosphatase 2A binding

0.58	GO:0000159	protein phosphatase type 2A complex
0.50	GO:0000775	chromosome, centromeric region
0.45	GO:0005829	cytosol
0.43	GO:0000922	spindle pole
0.40	GO:0005886	plasma membrane
0.39	GO:0005634	nucleus
0.38	GO:0070062	extracellular exosome
0.35	GO:0043195	terminal bouton
0.34	GO:0014069	postsynaptic density
0.33	GO:0005739	mitochondrion

0.72

GO:0004721

sp|P62736|ACTA_HUMAN
Actin, aortic smooth muscle
Search

ACTA2

0.97	Actin aortic smooth muscle

0.82	GO:0090131	mesenchyme migration
0.66	GO:0010628	positive regulation of gene expression
0.44	GO:0072144	glomerular mesangial cell development
0.42	GO:0008015	blood circulation
0.41	GO:0006936	muscle contraction
0.40	GO:0009615	response to virus
0.39	GO:0003015	heart process
0.39	GO:0035296	regulation of tube diameter
0.39	GO:0003018	vascular process in circulatory system
0.39	GO:0061870	positive regulation of hepatic stellate cell migration

0.54	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.40	GO:0019901	protein kinase binding
0.36	GO:0005200	structural constituent of cytoskeleton

0.77	GO:0030175	filopodium
0.75	GO:0030027	lamellipodium
0.73	GO:0044297	cell body
0.46	GO:0005737	cytoplasm
0.42	GO:0005856	cytoskeleton
0.39	GO:0099512	supramolecular fiber
0.39	GO:0070062	extracellular exosome
0.37	GO:0043234	protein complex
0.37	GO:0044422	organelle part
0.33	GO:0071944	cell periphery

sp|P62745|RHOB_HUMAN
Rho-related GTP-binding protein RhoB
Search

RHOB

0.48	Rho-related GTP-binding protein RhoB

0.76	GO:0007264	small GTPase mediated signal transduction
0.54	GO:0061154	endothelial tube morphogenesis
0.53	GO:0008333	endosome to lysosome transport
0.52	GO:0071479	cellular response to ionizing radiation
0.52	GO:0070301	cellular response to hydrogen peroxide
0.52	GO:0010595	positive regulation of endothelial cell migration
0.52	GO:0000281	mitotic cytokinesis
0.52	GO:0045766	positive regulation of angiogenesis
0.51	GO:0030336	negative regulation of cell migration
0.50	GO:0043065	positive regulation of apoptotic process

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.52	GO:0019003	GDP binding
0.38	GO:0019900	kinase binding
0.34	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
0.32	GO:0022857	transmembrane transporter activity

0.52	GO:0097610	cell surface furrow
0.51	GO:0032155	cell division site part
0.50	GO:0005770	late endosome
0.50	GO:0005769	early endosome
0.49	GO:0010008	endosome membrane
0.43	GO:0005634	nucleus
0.41	GO:0005886	plasma membrane
0.41	GO:0070451	cell hair
0.40	GO:0045179	apical cortex
0.40	GO:0044291	cell-cell contact zone

0.34

EC:1.2.1

GO:0016620

sp|P62750|RL23A_HUMAN
60S ribosomal protein L23a
Search

RPL23A

0.86	Ribosomal protein L23A, pseudogene 3

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.49	GO:0000027	ribosomal large subunit assembly
0.43	GO:0008283	cell proliferation
0.41	GO:0031016	pancreas development
0.39	GO:0051726	regulation of cell cycle
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0007250	activation of NF-kappaB-inducing kinase activity

0.64	GO:0003735	structural constituent of ribosome
0.43	GO:0045296	cadherin binding
0.42	GO:0003723	RNA binding
0.33	GO:0004672	protein kinase activity
0.33	GO:0008270	zinc ion binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005840	ribosome
0.47	GO:0044445	cytosolic part
0.42	GO:0031932	TORC2 complex
0.41	GO:0044446	intracellular organelle part
0.39	GO:0005634	nucleus
0.36	GO:0070062	extracellular exosome
0.34	GO:0031974	membrane-enclosed lumen

sp|P62753|RS6_HUMAN
40S ribosomal protein S6
Search

RPS6

0.63	Ribosomal protein S6 (Fragment)

0.60	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.52	GO:0002309	T cell proliferation involved in immune response
0.52	GO:0022605	oogenesis stage
0.52	GO:0006924	activation-induced cell death of T cells
0.50	GO:0042274	ribosomal small subunit biogenesis
0.50	GO:0048821	erythrocyte development
0.49	GO:0033077	T cell differentiation in thymus

0.63	GO:0003735	structural constituent of ribosome
0.46	GO:0019901	protein kinase binding
0.34	GO:0003729	mRNA binding

0.61	GO:0005840	ribosome
0.50	GO:0030425	dendrite
0.49	GO:0044445	cytosolic part
0.48	GO:0005844	polysome
0.48	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0044297	cell body
0.47	GO:0036464	cytoplasmic ribonucleoprotein granule
0.45	GO:0005730	nucleolus
0.44	GO:0005783	endoplasmic reticulum
0.33	GO:0005654	nucleoplasm

sp|P62760|VISL1_HUMAN
Visinin-like protein 1
Search

VSNL1

0.95	Visinin like 1

0.55	GO:0046676	negative regulation of insulin secretion
0.55	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus
0.54	GO:0045921	positive regulation of exocytosis
0.42	GO:0065009	regulation of molecular function
0.40	GO:0007165	signal transduction
0.34	GO:0007417	central nervous system development

0.70	GO:0005509	calcium ion binding
0.48	GO:0005246	calcium channel regulator activity
0.34	GO:0008022	protein C-terminus binding
0.34	GO:0019904	protein domain specific binding

0.47	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|P62805|H4_HUMAN
Histone H4
Search

sp|P62807|H2B1C_HUMAN
Histone H2B type 1-C/E/F/G/I
Search

0.86	Histone H2B type 1-H

0.52	GO:0006334	nucleosome assembly
0.38	GO:0002227	innate immune response in mucosa
0.38	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.37	GO:0019731	antibacterial humoral response
0.37	GO:0050830	defense response to Gram-positive bacterium
0.35	GO:0016567	protein ubiquitination
0.33	GO:0006352	DNA-templated transcription, initiation

0.74	GO:0046982	protein heterodimerization activity
0.55	GO:0003677	DNA binding
0.39	GO:0097677	STAT family protein binding
0.37	GO:0044389	ubiquitin-like protein ligase binding
0.36	GO:0042802	identical protein binding

0.74	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.44	GO:0005829	cytosol
0.44	GO:0031974	membrane-enclosed lumen
0.37	GO:0005615	extracellular space
0.36	GO:1903561	extracellular vesicle
0.35	GO:0043234	protein complex

sp|P62820|RAB1A_HUMAN
Ras-related protein Rab-1A
Search

RAB1A

0.86	Ras-associated binding-GTPase 1a4

0.53	GO:0072606	interleukin-8 secretion
0.53	GO:0030252	growth hormone secretion
0.52	GO:0032402	melanosome transport
0.51	GO:0034446	substrate adhesion-dependent cell spreading
0.51	GO:0090110	cargo loading into COPII-coated vesicle
0.51	GO:1903020	positive regulation of glycoprotein metabolic process
0.50	GO:0047496	vesicle transport along microtubule
0.49	GO:0000045	autophagosome assembly
0.49	GO:0016477	cell migration
0.48	GO:0007030	Golgi organization

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0045296	cadherin binding

0.51	GO:0042470	melanosome
0.49	GO:0000139	Golgi membrane
0.43	GO:0005789	endoplasmic reticulum membrane
0.39	GO:0005769	early endosome
0.37	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome
0.35	GO:0030133	transport vesicle
0.34	GO:0043025	neuronal cell body
0.34	GO:0099503	secretory vesicle
0.34	GO:0098793	presynapse

sp|P62826|RAN_HUMAN
GTP-binding nuclear protein Ran
Search

RAN

0.69	GTP-binding nuclear protein Ran

0.72	GO:0006913	nucleocytoplasmic transport
0.65	GO:0015031	protein transport
0.52	GO:0051030	snRNA transport
0.51	GO:0006404	RNA import into nucleus
0.51	GO:0034504	protein localization to nucleus
0.50	GO:0033750	ribosome localization
0.49	GO:0071166	ribonucleoprotein complex localization
0.49	GO:0051169	nuclear transport
0.49	GO:0051656	establishment of organelle localization
0.48	GO:0072594	establishment of protein localization to organelle

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.46	GO:0019003	GDP binding
0.45	GO:0070883	pre-miRNA binding
0.44	GO:0045296	cadherin binding
0.43	GO:0000287	magnesium ion binding
0.42	GO:0046982	protein heterodimerization activity
0.38	GO:0061676	importin-alpha family protein binding
0.38	GO:0045505	dynein intermediate chain binding
0.36	GO:0019904	protein domain specific binding

0.61	GO:0005634	nucleus
0.47	GO:0042565	RNA nuclear export complex
0.45	GO:0030496	midbody
0.45	GO:0055037	recycling endosome
0.45	GO:0005814	centriole
0.42	GO:0000785	chromatin
0.41	GO:0031967	organelle envelope
0.41	GO:0042470	melanosome
0.41	GO:0070013	intracellular organelle lumen
0.38	GO:0002177	manchette

sp|P62829|RL23_HUMAN
60S ribosomal protein L23
Search

RPL23

0.64	Ribosomal protein L23

0.58	GO:0043043	peptide biosynthetic process
0.53	GO:0044267	cellular protein metabolic process
0.52	GO:0010467	gene expression
0.51	GO:0009059	macromolecule biosynthetic process
0.47	GO:0072717	cellular response to actinomycin D
0.46	GO:2000059	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.46	GO:1901798	positive regulation of signal transduction by p53 class mediator
0.45	GO:1904667	negative regulation of ubiquitin protein ligase activity
0.45	GO:0071157	negative regulation of cell cycle arrest
0.45	GO:0071158	positive regulation of cell cycle arrest

0.61	GO:0003735	structural constituent of ribosome
0.46	GO:1990948	ubiquitin ligase inhibitor activity
0.46	GO:0001223	transcription coactivator binding
0.44	GO:0070180	large ribosomal subunit rRNA binding
0.43	GO:0031625	ubiquitin protein ligase binding

0.59	GO:0005840	ribosome
0.44	GO:0005730	nucleolus
0.42	GO:0044445	cytosolic part
0.41	GO:0005654	nucleoplasm
0.38	GO:0043234	protein complex
0.37	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.36	GO:0098556	cytoplasmic side of rough endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P62834|RAP1A_HUMAN
Ras-related protein Rap-1A
Search

RAP1A

0.92	Ras-related protein O-Krev

0.61	GO:0007165	signal transduction
0.59	GO:0061028	establishment of endothelial barrier
0.59	GO:0071320	cellular response to cAMP
0.58	GO:1901888	regulation of cell junction assembly
0.57	GO:2000301	negative regulation of synaptic vesicle exocytosis
0.54	GO:2001214	positive regulation of vasculogenesis
0.53	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.51	GO:0010976	positive regulation of neuron projection development
0.45	GO:2000114	regulation of establishment of cell polarity
0.44	GO:0015031	protein transport

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.52	GO:0032403	protein complex binding
0.48	GO:0019003	GDP binding
0.48	GO:0017016	Ras GTPase binding
0.46	GO:0008565	protein transporter activity
0.38	GO:0005085	guanyl-nucleotide exchange factor activity
0.35	GO:0004708	MAP kinase kinase activity

0.53	GO:0030054	cell junction
0.52	GO:0032045	guanyl-nucleotide exchange factor complex
0.50	GO:0043209	myelin sheath
0.49	GO:0048471	perinuclear region of cytoplasm
0.48	GO:0043005	neuron projection
0.46	GO:0005811	lipid droplet
0.43	GO:0005829	cytosol
0.41	GO:0005886	plasma membrane
0.40	GO:0070062	extracellular exosome
0.39	GO:0005770	late endosome

0.35

GO:0004708

sp|P62837|UB2D2_HUMAN
Ubiquitin-conjugating enzyme E2 D2
Search

UBE2D2

0.65	Ubiquitin conjugating enzyme E2

0.46	GO:0000209	protein polyubiquitination
0.46	GO:0051865	protein autoubiquitination
0.39	GO:0045676	regulation of R7 cell differentiation
0.39	GO:0048132	female germ-line stem cell asymmetric division
0.38	GO:0016322	neuron remodeling
0.38	GO:0030718	germ-line stem cell population maintenance
0.38	GO:0001751	compound eye photoreceptor cell differentiation
0.38	GO:0007140	male meiotic nuclear division
0.38	GO:0031145	anaphase-promoting complex-dependent catabolic process
0.37	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0061631	ubiquitin conjugating enzyme activity
0.37	GO:0031625	ubiquitin protein ligase binding
0.37	GO:0061630	ubiquitin protein ligase activity
0.35	GO:0016874	ligase activity

0.43	GO:0000151	ubiquitin ligase complex
0.38	GO:0043234	protein complex
0.35	GO:0070062	extracellular exosome
0.34	GO:0005829	cytosol
0.33	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

0.35

GO:0016874

sp|P62841|RS15_HUMAN
40S ribosomal protein S15
Search

RPS15

0.69	Ribosomal protein S15

0.58	GO:0043043	peptide biosynthetic process
0.54	GO:0044267	cellular protein metabolic process
0.52	GO:0010467	gene expression
0.51	GO:0009059	macromolecule biosynthetic process
0.46	GO:0000028	ribosomal small subunit assembly
0.43	GO:0043009	chordate embryonic development
0.38	GO:0000056	ribosomal small subunit export from nucleus
0.37	GO:0097421	liver regeneration
0.37	GO:0001649	osteoblast differentiation
0.36	GO:0016072	rRNA metabolic process

0.62	GO:0003735	structural constituent of ribosome
0.56	GO:0003723	RNA binding
0.34	GO:0005515	protein binding
0.32	GO:0003677	DNA binding

0.67	GO:0015935	small ribosomal subunit
0.45	GO:0022626	cytosolic ribosome
0.36	GO:0005925	focal adhesion
0.36	GO:0005654	nucleoplasm
0.36	GO:0098556	cytoplasmic side of rough endoplasmic reticulum membrane

sp|P62847|RS24_HUMAN
40S ribosomal protein S24
Search

RPS24

0.69	40S ribosomal protein S24

0.60	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.46	GO:0042274	ribosomal small subunit biogenesis
0.44	GO:0016072	rRNA metabolic process
0.42	GO:0034101	erythrocyte homeostasis
0.36	GO:0060215	primitive hemopoiesis
0.36	GO:0060216	definitive hemopoiesis
0.35	GO:0097421	liver regeneration

0.64	GO:0003735	structural constituent of ribosome
0.36	GO:0031369	translation initiation factor binding
0.34	GO:0032403	protein complex binding
0.33	GO:0003743	translation initiation factor activity

0.61	GO:0005840	ribosome
0.45	GO:0044445	cytosolic part
0.40	GO:0044446	intracellular organelle part
0.34	GO:0005634	nucleus
0.33	GO:0043233	organelle lumen
0.30	GO:0016020	membrane

sp|P62851|RS25_HUMAN
40S ribosomal protein S25
Search

RPS25

0.71	Ribosomal protein S25 (Predicted)

0.36	GO:0034198	cellular response to amino acid starvation
0.36	GO:0000028	ribosomal small subunit assembly
0.36	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.35	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.35	GO:0019083	viral transcription
0.35	GO:0006413	translational initiation
0.35	GO:0006364	rRNA processing

0.35	GO:0003723	RNA binding
0.34	GO:0003735	structural constituent of ribosome
0.34	GO:0005515	protein binding

0.61	GO:0005840	ribosome
0.45	GO:0005730	nucleolus
0.44	GO:0044445	cytosolic part
0.39	GO:0031012	extracellular matrix
0.38	GO:0070062	extracellular exosome
0.36	GO:0005844	polysome
0.35	GO:0005654	nucleoplasm

sp|P62854|RS26_HUMAN
40S ribosomal protein S26
Search

RPS26

0.68	40S ribosomal protein S26

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.43	GO:0033119	negative regulation of RNA splicing
0.35	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.33	GO:0036211	protein modification process

0.64	GO:0003735	structural constituent of ribosome
0.48	GO:0003729	mRNA binding
0.41	GO:0045296	cadherin binding
0.35	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.34	GO:0097199	cysteine-type endopeptidase activity involved in apoptotic signaling pathway
0.33	GO:0004716	signal transducer, downstream of receptor, with protein tyrosine kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005840	ribosome
0.48	GO:0044445	cytosolic part
0.44	GO:0005844	polysome
0.43	GO:0098556	cytoplasmic side of rough endoplasmic reticulum membrane
0.36	GO:0070062	extracellular exosome
0.33	GO:0005654	nucleoplasm
0.30	GO:0016021	integral component of membrane

0.35

EC:2.7.10.1

GO:0004714

sp|P62857|RS28_HUMAN
40S ribosomal protein S28
Search

RPS28

0.82	Ribosomal protein S28 pseudogene 9

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.48	GO:0042274	ribosomal small subunit biogenesis
0.46	GO:0016072	rRNA metabolic process
0.44	GO:0042255	ribosome assembly
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.33	GO:0019083	viral transcription

0.64	GO:0003735	structural constituent of ribosome
0.39	GO:0003723	RNA binding
0.34	GO:0004815	aspartate-tRNA ligase activity
0.34	GO:0005515	protein binding
0.33	GO:0051539	4 iron, 4 sulfur cluster binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0046872	metal ion binding
0.32	GO:0016787	hydrolase activity

0.61	GO:0005840	ribosome
0.49	GO:0005844	polysome
0.48	GO:0044445	cytosolic part
0.42	GO:0098556	cytoplasmic side of rough endoplasmic reticulum membrane
0.36	GO:0070062	extracellular exosome
0.35	GO:0005634	nucleus
0.34	GO:0019008	molybdopterin synthase complex
0.33	GO:0043233	organelle lumen
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:6.1.1.12

GO:0004815

sp|P62873|GBB1_HUMAN
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
Search

GNB1

0.91	Guanine nucleotide-binding protein beta subunit

0.61	GO:0007165	signal transduction
0.52	GO:0060041	retina development in camera-type eye
0.51	GO:0050909	sensory perception of taste
0.50	GO:0008283	cell proliferation
0.41	GO:0010659	cardiac muscle cell apoptotic process
0.40	GO:0070208	protein heterotrimerization
0.39	GO:0071456	cellular response to hypoxia
0.39	GO:0048920	posterior lateral line neuromast primordium migration
0.39	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.37	GO:0071417	cellular response to organonitrogen compound

0.52	GO:0032403	protein complex binding
0.50	GO:0051020	GTPase binding
0.46	GO:0003924	GTPase activity
0.41	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity
0.41	GO:0031702	type 1 angiotensin receptor binding
0.40	GO:0030507	spectrin binding
0.39	GO:0004871	signal transducer activity
0.36	GO:0005246	calcium channel regulator activity

0.55	GO:0043209	myelin sheath
0.52	GO:0001750	photoreceptor outer segment
0.52	GO:1905360	GTPase complex
0.51	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.45	GO:0098797	plasma membrane protein complex
0.41	GO:0060170	ciliary membrane
0.40	GO:0048471	perinuclear region of cytoplasm
0.40	GO:0044297	cell body
0.40	GO:0001917	photoreceptor inner segment
0.39	GO:0005765	lysosomal membrane

0.41

EC:3.1.4.39

GO:0047391

sp|P62875|RPAB5_HUMAN
DNA-directed RNA polymerases I, II, and III subunit RPABC5
Search

POLR2L

0.90	RNA polymerase II subunit L

0.58	GO:0006351	transcription, DNA-templated
0.35	GO:0035019	somatic stem cell population maintenance
0.34	GO:0032481	positive regulation of type I interferon production
0.34	GO:0060964	regulation of gene silencing by miRNA
0.34	GO:0045815	positive regulation of gene expression, epigenetic
0.34	GO:0006356	regulation of transcription by RNA polymerase I
0.34	GO:0008543	fibroblast growth factor receptor signaling pathway
0.34	GO:0016073	snRNA metabolic process
0.34	GO:0050434	positive regulation of viral transcription
0.34	GO:0006283	transcription-coupled nucleotide-excision repair

0.70	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.63	GO:0008270	zinc ion binding
0.55	GO:0003677	DNA binding
0.38	GO:0051087	chaperone binding

0.52	GO:0005665	DNA-directed RNA polymerase II, core complex
0.47	GO:0005736	DNA-directed RNA polymerase I complex
0.47	GO:0005666	DNA-directed RNA polymerase III complex
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.70

GO:0003899

sp|P62877|RBX1_HUMAN
E3 ubiquitin-protein ligase RBX1
Search

RBX1

0.78	SCF ubiquitin ligase Rbx1 component

0.53	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
0.53	GO:0045116	protein neddylation
0.48	GO:0006513	protein monoubiquitination
0.48	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
0.48	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.35	GO:0006293	nucleotide-excision repair, preincision complex stabilization
0.35	GO:0006294	nucleotide-excision repair, preincision complex assembly
0.35	GO:0010265	SCF complex assembly
0.35	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion
0.35	GO:0000717	nucleotide-excision repair, DNA duplex unwinding

0.63	GO:0008270	zinc ion binding
0.56	GO:0019788	NEDD8 transferase activity
0.55	GO:0097602	cullin family protein binding
0.49	GO:0061630	ubiquitin protein ligase activity
0.47	GO:0016874	ligase activity
0.46	GO:0031625	ubiquitin protein ligase binding
0.44	GO:0008134	transcription factor binding
0.36	GO:0032403	protein complex binding
0.35	GO:0008190	eukaryotic initiation factor 4E binding

0.56	GO:0031467	Cul7-RING ubiquitin ligase complex
0.55	GO:0031462	Cul2-RING ubiquitin ligase complex
0.53	GO:0080008	Cul4-RING E3 ubiquitin ligase complex
0.53	GO:0019005	SCF ubiquitin ligase complex
0.52	GO:0031463	Cul3-RING ubiquitin ligase complex
0.50	GO:0031466	Cul5-RING ubiquitin ligase complex
0.47	GO:0000152	nuclear ubiquitin ligase complex
0.43	GO:0005654	nucleoplasm
0.42	GO:0005829	cytosol
0.38	GO:0030891	VCB complex

0.47

GO:0016874

sp|P62879|GBB2_HUMAN
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2
Search

GNB2

0.83	Guanine nucleotide-binding protein beta subunit

0.61	GO:0007165	signal transduction
0.50	GO:0060041	retina development in camera-type eye
0.49	GO:0050909	sensory perception of taste
0.49	GO:0008283	cell proliferation
0.41	GO:0010659	cardiac muscle cell apoptotic process
0.40	GO:0070208	protein heterotrimerization
0.39	GO:0071456	cellular response to hypoxia
0.39	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.37	GO:0071417	cellular response to organonitrogen compound
0.37	GO:0033762	response to glucagon

0.55	GO:0032403	protein complex binding
0.54	GO:0051020	GTPase binding
0.45	GO:0003924	GTPase activity
0.41	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity
0.40	GO:0031702	type 1 angiotensin receptor binding
0.40	GO:0004871	signal transducer activity
0.40	GO:0005246	calcium channel regulator activity
0.39	GO:0030507	spectrin binding

0.59	GO:0043209	myelin sheath
0.51	GO:1905360	GTPase complex
0.51	GO:0001750	photoreceptor outer segment
0.50	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.50	GO:0048471	perinuclear region of cytoplasm
0.45	GO:0098797	plasma membrane protein complex
0.42	GO:0044297	cell body
0.40	GO:0005765	lysosomal membrane
0.40	GO:0060170	ciliary membrane
0.39	GO:0001917	photoreceptor inner segment

0.41

EC:3.1.4.39

GO:0047391

sp|P62888|RL30_HUMAN
60S ribosomal protein L30
Search

RPL30

0.74	Ribosomal protein L30

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.46	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.44	GO:0050829	defense response to Gram-negative bacterium
0.43	GO:0031640	killing of cells of other organism
0.36	GO:1904571	positive regulation of selenocysteine incorporation
0.35	GO:0097421	liver regeneration
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

0.64	GO:0003735	structural constituent of ribosome
0.39	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.61	GO:0005840	ribosome
0.45	GO:0044445	cytosolic part
0.44	GO:0005844	polysome
0.40	GO:0044446	intracellular organelle part
0.39	GO:0005634	nucleus
0.36	GO:0031012	extracellular matrix
0.36	GO:0005925	focal adhesion
0.36	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

sp|P62891|RL39_HUMAN
60S ribosomal protein L39
Search

RPL39

0.84	Angiomotin like 2

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.41	GO:0007283	spermatogenesis
0.38	GO:0002227	innate immune response in mucosa
0.38	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.37	GO:0019731	antibacterial humoral response
0.37	GO:0050830	defense response to Gram-positive bacterium
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

0.64	GO:0003735	structural constituent of ribosome
0.40	GO:0003723	RNA binding
0.34	GO:0005515	protein binding

0.61	GO:0005840	ribosome
0.45	GO:0044445	cytosolic part
0.40	GO:0044446	intracellular organelle part
0.36	GO:0005615	extracellular space
0.34	GO:0005844	polysome

sp|P62899|RL31_HUMAN
60S ribosomal protein L31
Search

RPL31

0.69	Ribosomal protein L31

0.58	GO:0043043	peptide biosynthetic process
0.54	GO:0044267	cellular protein metabolic process
0.52	GO:0010467	gene expression
0.51	GO:0009059	macromolecule biosynthetic process
0.35	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.34	GO:0006298	mismatch repair
0.34	GO:0016072	rRNA metabolic process
0.34	GO:0042254	ribosome biogenesis

0.62	GO:0003735	structural constituent of ribosome
0.34	GO:0003796	lysozyme activity
0.34	GO:0005515	protein binding
0.34	GO:0003723	RNA binding
0.33	GO:0004519	endonuclease activity

0.60	GO:0005840	ribosome
0.47	GO:0044445	cytosolic part
0.47	GO:0005844	polysome
0.41	GO:0044446	intracellular organelle part
0.37	GO:0005925	focal adhesion
0.37	GO:0070062	extracellular exosome
0.35	GO:0005791	rough endoplasmic reticulum
0.34	GO:0098562	cytoplasmic side of membrane
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0098588	bounding membrane of organelle

0.34

EC:3.2.1.17

GO:0003796

sp|P62906|RL10A_HUMAN
60S ribosomal protein L10a
Search

RPL10A

0.55	Ribosomal protein (Fragment)

0.58	GO:0043043	peptide biosynthetic process
0.54	GO:0044267	cellular protein metabolic process
0.52	GO:0010467	gene expression
0.51	GO:0009059	macromolecule biosynthetic process
0.44	GO:0042273	ribosomal large subunit biogenesis
0.41	GO:0016072	rRNA metabolic process
0.35	GO:0045471	response to ethanol

0.61	GO:0003735	structural constituent of ribosome
0.57	GO:0003723	RNA binding
0.32	GO:0016787	hydrolase activity

0.67	GO:0015934	large ribosomal subunit
0.49	GO:0022626	cytosolic ribosome
0.49	GO:0042788	polysomal ribosome
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016787

sp|P62910|RL32_HUMAN
60S ribosomal protein L32
Search

RPL32

0.48	Ribosomal protein L32

0.58	GO:0043043	peptide biosynthetic process
0.54	GO:0044267	cellular protein metabolic process
0.52	GO:0010467	gene expression
0.51	GO:0009059	macromolecule biosynthetic process
0.38	GO:0097421	liver regeneration
0.37	GO:0071549	cellular response to dexamethasone stimulus
0.35	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.34	GO:0016072	rRNA metabolic process

0.61	GO:0003735	structural constituent of ribosome
0.34	GO:0003723	RNA binding

0.59	GO:0005840	ribosome
0.50	GO:0044445	cytosolic part
0.48	GO:0005844	polysome
0.43	GO:0044446	intracellular organelle part
0.35	GO:0005791	rough endoplasmic reticulum
0.34	GO:0098562	cytoplasmic side of membrane
0.34	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0098588	bounding membrane of organelle

sp|P62913|RL11_HUMAN
60S ribosomal protein L11
Search

RPL11

0.67	Ribosomal protein L11

0.59	GO:0043043	peptide biosynthetic process
0.56	GO:2000435	negative regulation of protein neddylation
0.55	GO:0044267	cellular protein metabolic process
0.54	GO:2000059	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.54	GO:1901796	regulation of signal transduction by p53 class mediator
0.54	GO:1904667	negative regulation of ubiquitin protein ligase activity
0.53	GO:0010467	gene expression
0.52	GO:0032092	positive regulation of protein binding
0.52	GO:0009059	macromolecule biosynthetic process
0.51	GO:0000027	ribosomal large subunit assembly

0.63	GO:0003735	structural constituent of ribosome
0.55	GO:1990948	ubiquitin ligase inhibitor activity
0.50	GO:0031625	ubiquitin protein ligase binding
0.50	GO:0008097	5S rRNA binding
0.35	GO:0042975	peroxisome proliferator activated receptor binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0032561	guanyl ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.60	GO:0005840	ribosome
0.50	GO:0005844	polysome
0.49	GO:0005730	nucleolus
0.48	GO:0044445	cytosolic part
0.47	GO:0005654	nucleoplasm
0.42	GO:0043234	protein complex
0.37	GO:0031012	extracellular matrix
0.36	GO:0070062	extracellular exosome
0.35	GO:0098556	cytoplasmic side of rough endoplasmic reticulum membrane

sp|P62917|RL8_HUMAN
60S ribosomal protein L8
Search

RPL8

0.80	Ribosomal protein L8

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.37	GO:1990090	cellular response to nerve growth factor stimulus
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.33	GO:0016072	rRNA metabolic process
0.33	GO:0042254	ribosome biogenesis

0.64	GO:0003735	structural constituent of ribosome
0.54	GO:0003723	RNA binding
0.33	GO:0005515	protein binding
0.32	GO:0016787	hydrolase activity

0.64	GO:0015934	large ribosomal subunit
0.52	GO:0022626	cytosolic ribosome
0.51	GO:0042788	polysomal ribosome
0.36	GO:0005925	focal adhesion
0.30	GO:0016020	membrane

0.32

GO:0016787

sp|P62937|PPIA_HUMAN
Peptidyl-prolyl cis-trans isomerase A
Search

PPIA

0.48	Peptidyl-prolyl cis-trans isomerase A

0.72	GO:0000413	protein peptidyl-prolyl isomerization
0.68	GO:0006457	protein folding
0.50	GO:0045069	regulation of viral genome replication
0.41	GO:0034389	lipid particle organization
0.41	GO:1903902	positive regulation of viral life cycle
0.40	GO:0050714	positive regulation of protein secretion
0.37	GO:0030182	neuron differentiation
0.36	GO:0019061	uncoating of virus
0.35	GO:0035722	interleukin-12-mediated signaling pathway
0.35	GO:0043312	neutrophil degranulation

0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.42	GO:0016018	cyclosporin A binding
0.35	GO:0046790	virion binding
0.35	GO:0005515	protein binding
0.34	GO:0003723	RNA binding
0.32	GO:0003677	DNA binding

0.43	GO:0005829	cytosol
0.43	GO:0005576	extracellular region
0.41	GO:0005634	nucleus
0.37	GO:0043209	myelin sheath
0.36	GO:0005925	focal adhesion
0.35	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen
0.34	GO:0030496	midbody
0.30	GO:0016020	membrane

0.72

GO:0003755

sp|P62942|FKB1A_HUMAN
Peptidyl-prolyl cis-trans isomerase FKBP1A
Search

0.60	Peptidyl-prolyl cis-trans isomerase FKBP1A

0.86	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity
0.85	GO:1990000	amyloid fibril formation
0.85	GO:0007183	SMAD protein complex assembly
0.85	GO:0060347	heart trabecula formation
0.85	GO:0031000	response to caffeine
0.84	GO:1902991	regulation of amyloid precursor protein catabolic process
0.83	GO:0032925	regulation of activin receptor signaling pathway
0.83	GO:0042098	T cell proliferation
0.82	GO:0055010	ventricular cardiac muscle tissue morphogenesis
0.80	GO:0032092	positive regulation of protein binding

0.85	GO:0048185	activin binding
0.81	GO:0005528	FK506 binding
0.80	GO:0044325	ion channel binding
0.80	GO:0046332	SMAD binding
0.79	GO:0019855	calcium channel inhibitor activity
0.74	GO:0034713	type I transforming growth factor beta receptor binding
0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.71	GO:0030544	Hsp70 protein binding
0.71	GO:0042803	protein homodimerization activity
0.60	GO:0019899	enzyme binding

0.88	GO:1990425	ryanodine receptor complex
0.81	GO:0031312	extrinsic component of organelle membrane
0.79	GO:0030018	Z disc
0.76	GO:0098562	cytoplasmic side of membrane
0.75	GO:0014802	terminal cisterna
0.72	GO:0070062	extracellular exosome
0.69	GO:0043679	axon terminus
0.69	GO:0005829	cytosol

0.72

GO:0003755

sp|P62945|RL41_HUMAN
60S ribosomal protein L41
Search

RPL41

0.97	Ribosomal protein L41 containing protein, expressed

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.34	GO:0016070	RNA metabolic process
0.34	GO:0034654	nucleobase-containing compound biosynthetic process
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.33	GO:0019083	viral transcription
0.33	GO:0055085	transmembrane transport
0.33	GO:0034655	nucleobase-containing compound catabolic process

0.64	GO:0003735	structural constituent of ribosome
0.40	GO:0003730	mRNA 3'-UTR binding
0.40	GO:0048027	mRNA 5'-UTR binding
0.36	GO:0003899	DNA-directed 5'-3' RNA polymerase activity
0.34	GO:0003677	DNA binding
0.32	GO:0016301	kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005840	ribosome
0.40	GO:0044445	cytosolic part
0.40	GO:0005844	polysome
0.38	GO:0044446	intracellular organelle part
0.35	GO:0005634	nucleus
0.35	GO:0043233	organelle lumen
0.34	GO:0005694	chromosome
0.32	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.36

GO:0003899

sp|P62952|BLCAP_HUMAN
Bladder cancer-associated protein
Search

BLCAP

0.97	Bladder cancer-associated protein (Fragment)

0.55	GO:0030262	apoptotic nuclear changes
0.38	GO:0007049	cell cycle

0.33

GO:0005515

protein binding

0.30

GO:0044425

membrane part

sp|P62955|CCG7_HUMAN
Voltage-dependent calcium channel gamma-7 subunit
Search

CACNG7

0.46	Multifunctional fusion protein (Fragment)

0.76	GO:0034765	regulation of ion transmembrane transport
0.75	GO:0070588	calcium ion transmembrane transport
0.56	GO:1900449	regulation of glutamate receptor signaling pathway
0.56	GO:0099601	regulation of neurotransmitter receptor activity
0.54	GO:0022898	regulation of transmembrane transporter activity
0.48	GO:0019226	transmission of nerve impulse

0.77	GO:0005262	calcium channel activity
0.73	GO:0022832	voltage-gated channel activity
0.71	GO:0022839	ion gated channel activity
0.70	GO:0008381	mechanosensitive ion channel activity
0.47	GO:0016247	channel regulator activity

0.50	GO:0032281	AMPA glutamate receptor complex
0.34	GO:0014069	postsynaptic density

sp|P62979|RS27A_HUMAN
Ubiquitin-40S ribosomal protein S27a
Search

RPS27A

0.66	Epididymis luminal protein 112

0.60	GO:0006518	peptide metabolic process
0.59	GO:0043604	amide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.54	GO:1901566	organonitrogen compound biosynthetic process
0.54	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.36	GO:0006301	postreplication repair
0.35	GO:0035635	entry of bacterium into host cell
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.35	GO:0035666	TRIF-dependent toll-like receptor signaling pathway

0.63	GO:0003735	structural constituent of ribosome
0.36	GO:0046872	metal ion binding
0.33	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.61	GO:0005840	ribosome
0.50	GO:0043209	myelin sheath
0.46	GO:0044445	cytosolic part
0.41	GO:0044446	intracellular organelle part
0.36	GO:0005634	nucleus
0.36	GO:0070013	intracellular organelle lumen
0.36	GO:0070062	extracellular exosome
0.34	GO:0030139	endocytic vesicle
0.34	GO:0012506	vesicle membrane
0.34	GO:0005768	endosome

sp|P62987|RL40_HUMAN
Ubiquitin-60S ribosomal protein L40
Search

UBA52

0.63	Anopheles stephensi ubiquitin

0.60	GO:0006518	peptide metabolic process
0.59	GO:0043604	amide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:1901566	organonitrogen compound biosynthetic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.38	GO:0017085	response to insecticide
0.36	GO:0007623	circadian rhythm
0.35	GO:0035635	entry of bacterium into host cell
0.35	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition

0.64	GO:0003735	structural constituent of ribosome
0.34	GO:0031386	protein tag
0.33	GO:0005515	protein binding

0.61	GO:0005840	ribosome
0.46	GO:0005829	cytosol
0.43	GO:0005783	endoplasmic reticulum
0.43	GO:0005654	nucleoplasm
0.38	GO:0005886	plasma membrane
0.37	GO:0005765	lysosomal membrane
0.36	GO:0043209	myelin sheath
0.36	GO:0070062	extracellular exosome
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0030666	endocytic vesicle membrane

sp|P62993|GRB2_HUMAN
Growth factor receptor-bound protein 2
Search

GRB2

0.96	Growth factor receptor bound protein 2

0.83	GO:0007265	Ras protein signal transduction
0.57	GO:0008286	insulin receptor signaling pathway
0.56	GO:0031623	receptor internalization
0.56	GO:0071479	cellular response to ionizing radiation
0.56	GO:0042770	signal transduction in response to DNA damage
0.56	GO:2000379	positive regulation of reactive oxygen species metabolic process
0.55	GO:0060670	branching involved in labyrinthine layer morphogenesis
0.53	GO:0030838	positive regulation of actin filament polymerization
0.52	GO:0043408	regulation of MAPK cascade
0.51	GO:0009967	positive regulation of signal transduction

0.59	GO:0043560	insulin receptor substrate binding
0.59	GO:0005168	neurotrophin TRKA receptor binding
0.58	GO:0005154	epidermal growth factor receptor binding
0.56	GO:0001784	phosphotyrosine residue binding
0.56	GO:0046875	ephrin receptor binding
0.56	GO:0005070	SH3/SH2 adaptor activity
0.55	GO:0019903	protein phosphatase binding
0.53	GO:0017124	SH3 domain binding
0.52	GO:0019901	protein kinase binding
0.50	GO:0042802	identical protein binding

0.60	GO:0070436	Grb2-EGFR complex
0.54	GO:0008180	COP9 signalosome
0.52	GO:0005768	endosome
0.51	GO:0005911	cell-cell junction
0.51	GO:0012506	vesicle membrane
0.50	GO:0005730	nucleolus
0.49	GO:0005654	nucleoplasm
0.46	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.39	GO:0005794	Golgi apparatus
0.36	GO:0070062	extracellular exosome

0.46	EC:2.7.10.2	GO:0004715
0.35	KEGG:R04545	GO:0046934

sp|P62995|TRA2B_HUMAN
Transformer-2 protein homolog beta
Search

TRA2B

0.97	Transformer-2 protein like protein beta

0.58	GO:0021796	cerebral cortex regionalization
0.58	GO:1990403	embryonic brain development
0.58	GO:0048026	positive regulation of mRNA splicing, via spliceosome
0.57	GO:0048025	negative regulation of mRNA splicing, via spliceosome
0.56	GO:0071333	cellular response to glucose stimulus
0.55	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.51	GO:0000398	mRNA splicing, via spliceosome
0.50	GO:0051259	protein oligomerization
0.37	GO:0000302	response to reactive oxygen species
0.36	GO:0006508	proteolysis

0.59	GO:0003723	RNA binding
0.52	GO:0019904	protein domain specific binding
0.50	GO:0042802	identical protein binding
0.37	GO:0008233	peptidase activity
0.34	GO:0003872	6-phosphofructokinase activity

0.54	GO:0005637	nuclear inner membrane
0.52	GO:0005681	spliceosomal complex
0.49	GO:0005654	nucleoplasm
0.37	GO:0048471	perinuclear region of cytoplasm
0.30	GO:0031224	intrinsic component of membrane

0.37

GO:0008233

sp|P63000|RAC1_HUMAN
Ras-related C3 botulinum toxin substrate 1
Search

RAC1

0.81	Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)

0.76	GO:0007264	small GTPase mediated signal transduction
0.52	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading
0.52	GO:0032707	negative regulation of interleukin-23 production
0.51	GO:0048012	hepatocyte growth factor receptor signaling pathway
0.51	GO:0010592	positive regulation of lamellipodium assembly
0.51	GO:0060263	regulation of respiratory burst
0.50	GO:0051894	positive regulation of focal adhesion assembly
0.50	GO:0090023	positive regulation of neutrophil chemotaxis
0.50	GO:0097178	ruffle assembly
0.50	GO:0030032	lamellipodium assembly

0.67	GO:0003924	GTPase activity
0.65	GO:0005525	GTP binding
0.51	GO:0031996	thioesterase binding
0.47	GO:0019901	protein kinase binding
0.44	GO:0051022	Rho GDP-dissociation inhibitor binding
0.40	GO:0048306	calcium-dependent protein binding
0.40	GO:0030742	GTP-dependent protein binding
0.39	GO:0051117	ATPase binding
0.39	GO:0042826	histone deacetylase binding
0.38	GO:0017137	Rab GTPase binding

0.50	GO:0005884	actin filament
0.49	GO:0043197	dendritic spine
0.49	GO:0055038	recycling endosome membrane
0.49	GO:0032587	ruffle membrane
0.48	GO:0030027	lamellipodium
0.47	GO:0005802	trans-Golgi network
0.47	GO:0036464	cytoplasmic ribonucleoprotein granule
0.40	GO:0042470	melanosome
0.40	GO:0097732	9+2 non-motile cilium
0.40	GO:0030426	growth cone

0.34

EC:2.3.1.48

GO:0004402

sp|P63010|AP2B1_HUMAN
AP-2 complex subunit beta
Search

AP2B1

0.63	AP complex subunit beta

0.69	GO:0006886	intracellular protein transport
0.68	GO:0016192	vesicle-mediated transport
0.51	GO:0060976	coronary vasculature development
0.51	GO:0035904	aorta development
0.51	GO:0003281	ventricular septum development
0.50	GO:0051668	localization within membrane
0.49	GO:0043112	receptor metabolic process
0.46	GO:0098657	import into cell
0.40	GO:0048268	clathrin coat assembly
0.40	GO:0045807	positive regulation of endocytosis

0.79	GO:0030276	clathrin binding
0.38	GO:0032403	protein complex binding
0.35	GO:0019901	protein kinase binding
0.35	GO:0098748	endocytic adaptor activity
0.34	GO:0005048	signal sequence binding
0.32	GO:0005215	transporter activity

0.78	GO:0030131	clathrin adaptor complex
0.51	GO:0030128	clathrin coat of endocytic vesicle
0.50	GO:0030132	clathrin coat of coated pit
0.39	GO:0005794	Golgi apparatus
0.37	GO:0031984	organelle subcompartment
0.35	GO:0036020	endolysosome membrane
0.35	GO:0005829	cytosol
0.34	GO:0098793	presynapse

sp|P63027|VAMP2_HUMAN
Vesicle-associated membrane protein 2
Search

VAMP2

0.73	Chain A, Neuronal Synaptic Fusion Complex

0.69	GO:0016192	vesicle-mediated transport
0.58	GO:0061951	establishment of protein localization to plasma membrane
0.55	GO:0090174	organelle membrane fusion
0.55	GO:1903530	regulation of secretion by cell
0.54	GO:1903540	establishment of protein localization to postsynaptic membrane
0.54	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels
0.54	GO:0099637	neurotransmitter receptor transport
0.53	GO:0016050	vesicle organization
0.53	GO:0023056	positive regulation of signaling
0.53	GO:0097120	receptor localization to synapse

0.56	GO:0000149	SNARE binding
0.49	GO:0005516	calmodulin binding
0.49	GO:0005484	SNAP receptor activity
0.48	GO:0005543	phospholipid binding
0.41	GO:0008022	protein C-terminus binding
0.41	GO:0048306	calcium-dependent protein binding
0.39	GO:0044325	ion channel binding
0.39	GO:0017022	myosin binding
0.38	GO:0032403	protein complex binding
0.37	GO:0042802	identical protein binding

0.60	GO:0031201	SNARE complex
0.56	GO:0030141	secretory granule
0.55	GO:0048471	perinuclear region of cytoplasm
0.53	GO:0030672	synaptic vesicle membrane
0.50	GO:0005802	trans-Golgi network
0.49	GO:0000322	storage vacuole
0.48	GO:0030136	clathrin-coated vesicle
0.47	GO:0055037	recycling endosome
0.47	GO:0045335	phagocytic vesicle
0.46	GO:0009986	cell surface

0.34

EC:1.13.11

GO:0016702

sp|P63096|GNAI1_HUMAN
Guanine nucleotide-binding protein G(i) subunit alpha-1
Search

GNAI1

0.79	Guanine nucleotide binding protein alpha inhibiting 1

0.82	GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
0.57	GO:1904778	positive regulation of protein localization to cell cortex
0.54	GO:0060236	regulation of mitotic spindle organization
0.49	GO:0051301	cell division
0.44	GO:0007212	dopamine receptor signaling pathway
0.44	GO:0016239	positive regulation of macroautophagy
0.44	GO:1904321	response to forskolin
0.43	GO:0043949	regulation of cAMP-mediated signaling
0.43	GO:1901655	cellular response to ketone
0.42	GO:0046039	GTP metabolic process

0.81	GO:0031683	G-protein beta/gamma-subunit complex binding
0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.64	GO:0004871	signal transducer activity
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0031821	G-protein coupled serotonin receptor binding
0.38	GO:0032794	GTPase activating protein binding
0.38	GO:0000287	magnesium ion binding

0.57	GO:0030496	midbody
0.54	GO:0005813	centrosome
0.53	GO:0099738	cell cortex region
0.51	GO:0005730	nucleolus
0.47	GO:1905360	GTPase complex
0.46	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.42	GO:0098797	plasma membrane protein complex
0.41	GO:0000139	Golgi membrane
0.41	GO:0005789	endoplasmic reticulum membrane
0.37	GO:0045121	membrane raft

sp|P63098|CANB1_HUMAN
Calcineurin subunit B type 1
Search

PPP3R1

0.93	Calcineurin B regulatory subunit

0.46	GO:0051531	NFAT protein import into nucleus
0.45	GO:0033173	calcineurin-NFAT signaling cascade
0.45	GO:0060487	lung epithelial cell differentiation
0.44	GO:0001569	branching involved in blood vessel morphogenesis
0.44	GO:0022011	myelination in peripheral nervous system
0.44	GO:0001837	epithelial to mesenchymal transition
0.42	GO:0007507	heart development
0.41	GO:0006470	protein dephosphorylation
0.39	GO:0045944	positive regulation of transcription by RNA polymerase II
0.35	GO:1900739	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway

0.70	GO:0005509	calcium ion binding
0.42	GO:0016018	cyclosporin A binding
0.41	GO:0004721	phosphoprotein phosphatase activity
0.39	GO:0019904	protein domain specific binding
0.38	GO:0043130	ubiquitin binding
0.35	GO:0019899	enzyme binding
0.34	GO:0032440	2-alkenal reductase [NAD(P)] activity
0.34	GO:0005516	calmodulin binding

0.43	GO:0042383	sarcolemma
0.41	GO:0005955	calcineurin complex
0.36	GO:0005829	cytosol
0.33	GO:0005654	nucleoplasm
0.33	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.41

GO:0004721

sp|P63104|1433Z_HUMAN
14-3-3 protein zeta/delta
Search

YWHAZ

0.87	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta

0.52	GO:0090168	Golgi reassembly
0.51	GO:0051683	establishment of Golgi localization
0.48	GO:0006605	protein targeting
0.46	GO:0010941	regulation of cell death
0.46	GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway
0.45	GO:0051220	cytoplasmic sequestering of protein
0.44	GO:0035308	negative regulation of protein dephosphorylation
0.41	GO:0043085	positive regulation of catalytic activity
0.37	GO:0055114	oxidation-reduction process
0.36	GO:0006839	mitochondrial transport

0.77	GO:0019904	protein domain specific binding
0.52	GO:0045296	cadherin binding
0.49	GO:0044325	ion channel binding
0.49	GO:0042802	identical protein binding
0.48	GO:0019899	enzyme binding
0.45	GO:0050815	phosphoserine residue binding
0.45	GO:0008134	transcription factor binding
0.42	GO:0004497	monooxygenase activity
0.36	GO:0032403	protein complex binding
0.36	GO:0008022	protein C-terminus binding

0.44	GO:0048471	perinuclear region of cytoplasm
0.44	GO:0042470	melanosome
0.42	GO:0005634	nucleus
0.41	GO:0005739	mitochondrion
0.41	GO:0005829	cytosol
0.38	GO:0005925	focal adhesion
0.38	GO:0070062	extracellular exosome
0.36	GO:0072562	blood microparticle
0.36	GO:0030659	cytoplasmic vesicle membrane
0.35	GO:0017053	transcriptional repressor complex

sp|P63121|VP113_HUMAN
Endogenous retrovirus group K member 113 Pro protein
Search

PRT

0.37	Endogenous retrovirus group K member 7 Pro protein

0.60	GO:0006508	proteolysis
0.41	GO:0016032	viral process
0.40	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.40	GO:0006278	RNA-dependent DNA biosynthetic process
0.38	GO:0015074	DNA integration
0.33	GO:0051806	entry into cell of other organism involved in symbiotic interaction
0.33	GO:0044409	entry into host
0.33	GO:0006310	DNA recombination
0.33	GO:0008380	RNA splicing
0.33	GO:0006397	mRNA processing

0.69	GO:0070001	aspartic-type peptidase activity
0.64	GO:0004175	endopeptidase activity
0.50	GO:0003676	nucleic acid binding
0.41	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.40	GO:0008270	zinc ion binding
0.40	GO:0003964	RNA-directed DNA polymerase activity
0.38	GO:0005198	structural molecule activity
0.37	GO:0004170	dUTP diphosphatase activity
0.36	GO:0003887	DNA-directed DNA polymerase activity
0.35	GO:0010309	acireductone dioxygenase [iron(II)-requiring] activity

0.39	GO:0019028	viral capsid
0.35	GO:0036338	viral membrane
0.34	GO:0005886	plasma membrane
0.33	GO:0005681	spliceosomal complex
0.30	GO:0016021	integral component of membrane

0.41	EC:3.1.26.4	GO:0004523
0.37	KEGG:R02100	GO:0004170

sp|P63124|VPK04_HUMAN
Endogenous retrovirus group K member 104 Pro protein
Search

PRT

0.96	Endogenous retrovirus group K member 7 Pro protein

0.61	GO:0006508	proteolysis
0.42	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.41	GO:0006278	RNA-dependent DNA biosynthetic process
0.40	GO:0016032	viral process

0.70	GO:0070001	aspartic-type peptidase activity
0.65	GO:0004175	endopeptidase activity
0.51	GO:0003676	nucleic acid binding
0.43	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.42	GO:0003887	DNA-directed DNA polymerase activity
0.41	GO:0003964	RNA-directed DNA polymerase activity
0.40	GO:0008270	zinc ion binding
0.39	GO:0005198	structural molecule activity

0.41	GO:0019028	viral capsid
0.37	GO:0005886	plasma membrane

0.43

GO:0004523

sp|P63128|POK9_HUMAN
Endogenous retrovirus group K member 9 Pol protein
Search

0.59	GO:0006278	RNA-dependent DNA biosynthetic process
0.55	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.52	GO:0015074	DNA integration
0.50	GO:0016032	viral process
0.46	GO:0006508	proteolysis
0.40	GO:0006310	DNA recombination
0.38	GO:0051806	entry into cell of other organism involved in symbiotic interaction
0.38	GO:0044409	entry into host
0.32	GO:0055114	oxidation-reduction process

0.60	GO:0003964	RNA-directed DNA polymerase activity
0.57	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.55	GO:0008270	zinc ion binding
0.51	GO:0070001	aspartic-type peptidase activity
0.49	GO:0003676	nucleic acid binding
0.49	GO:0004175	endopeptidase activity
0.48	GO:0005198	structural molecule activity
0.40	GO:0003887	DNA-directed DNA polymerase activity
0.36	GO:0004170	dUTP diphosphatase activity
0.34	GO:0044823	retroviral integrase activity

0.51	GO:0019028	viral capsid
0.42	GO:0005886	plasma membrane
0.37	GO:0036338	viral membrane
0.30	GO:0016021	integral component of membrane

0.60	EC:2.7.7.49	GO:0003964
0.36	KEGG:R02100	GO:0004170

sp|P63132|PO113_HUMAN
Endogenous retrovirus group K member 113 Pol protein
Search

POL

0.30	Integrase DNA binding domain

0.69	GO:0006278	RNA-dependent DNA biosynthetic process
0.68	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.65	GO:0015074	DNA integration
0.46	GO:0006310	DNA recombination
0.44	GO:0044826	viral genome integration into host DNA
0.44	GO:0075713	establishment of integrated proviral latency
0.41	GO:0051806	entry into cell of other organism involved in symbiotic interaction
0.41	GO:0044409	entry into host
0.39	GO:0006508	proteolysis

0.71	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.69	GO:0003964	RNA-directed DNA polymerase activity
0.59	GO:0008270	zinc ion binding
0.50	GO:0003676	nucleic acid binding
0.41	GO:0004170	dUTP diphosphatase activity
0.41	GO:0070001	aspartic-type peptidase activity
0.40	GO:0003887	DNA-directed DNA polymerase activity
0.40	GO:0004175	endopeptidase activity
0.39	GO:0005198	structural molecule activity
0.32	GO:1901265	nucleoside phosphate binding

0.40	GO:0044423	virion part
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.71	EC:3.1.26.4	GO:0004523
0.41	KEGG:R02100	GO:0004170

sp|P63133|POK8_HUMAN
Endogenous retrovirus group K member 8 Pol protein
Search

POL

0.30	Integrase DNA binding domain

0.69	GO:0006278	RNA-dependent DNA biosynthetic process
0.68	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.65	GO:0015074	DNA integration
0.46	GO:0006310	DNA recombination
0.44	GO:0044826	viral genome integration into host DNA
0.44	GO:0075713	establishment of integrated proviral latency
0.41	GO:0051806	entry into cell of other organism involved in symbiotic interaction
0.41	GO:0044409	entry into host
0.39	GO:0006508	proteolysis

0.71	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.69	GO:0003964	RNA-directed DNA polymerase activity
0.60	GO:0008270	zinc ion binding
0.50	GO:0003676	nucleic acid binding
0.41	GO:0004170	dUTP diphosphatase activity
0.41	GO:0070001	aspartic-type peptidase activity
0.40	GO:0003887	DNA-directed DNA polymerase activity
0.40	GO:0004175	endopeptidase activity
0.39	GO:0005198	structural molecule activity
0.32	GO:1901265	nucleoside phosphate binding

0.40	GO:0044423	virion part
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.71	EC:3.1.26.4	GO:0004523
0.41	KEGG:R02100	GO:0004170

sp|P63135|POK7_HUMAN
Endogenous retrovirus group K member 7 Pol protein
Search

0.95	Endogenous retrovirus group K member 7 Pol protein

0.61	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.61	GO:0006278	RNA-dependent DNA biosynthetic process
0.60	GO:0015074	DNA integration
0.58	GO:0045026	plasma membrane fusion
0.56	GO:0006310	DNA recombination

0.64	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.61	GO:0003964	RNA-directed DNA polymerase activity
0.56	GO:0008270	zinc ion binding
0.53	GO:0005198	structural molecule activity
0.49	GO:0003677	DNA binding

0.56	GO:0036338	viral membrane
0.46	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.64

GO:0004523

sp|P63136|POK25_HUMAN
Endogenous retrovirus group K member 25 Pol protein
Search

POL

0.30	Integrase DNA binding domain

0.69	GO:0006278	RNA-dependent DNA biosynthetic process
0.68	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.65	GO:0015074	DNA integration
0.46	GO:0006310	DNA recombination
0.45	GO:0044826	viral genome integration into host DNA
0.45	GO:0075713	establishment of integrated proviral latency
0.41	GO:0051806	entry into cell of other organism involved in symbiotic interaction
0.41	GO:0044409	entry into host
0.39	GO:0006508	proteolysis

0.71	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.69	GO:0003964	RNA-directed DNA polymerase activity
0.60	GO:0008270	zinc ion binding
0.50	GO:0003676	nucleic acid binding
0.42	GO:0070001	aspartic-type peptidase activity
0.41	GO:0004170	dUTP diphosphatase activity
0.40	GO:0004175	endopeptidase activity
0.40	GO:0003887	DNA-directed DNA polymerase activity
0.40	GO:0005198	structural molecule activity
0.35	GO:0044823	retroviral integrase activity

0.40	GO:0019028	viral capsid
0.37	GO:0036338	viral membrane
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.71	EC:3.1.26.4	GO:0004523
0.41	KEGG:R02100	GO:0004170

sp|P63145|GAK24_HUMAN
Endogenous retrovirus group K member 24 Gag polyprotein
Search

0.20	Endogenous retrovirus group K member 9 Gag polyprotein

0.63	GO:0016032	viral process
0.43	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.43	GO:0006278	RNA-dependent DNA biosynthetic process
0.41	GO:0006508	proteolysis
0.40	GO:0015074	DNA integration
0.37	GO:0051806	entry into cell of other organism involved in symbiotic interaction
0.37	GO:0044409	entry into host
0.36	GO:0006310	DNA recombination

0.63	GO:0008270	zinc ion binding
0.61	GO:0005198	structural molecule activity
0.51	GO:0003676	nucleic acid binding
0.45	GO:0070001	aspartic-type peptidase activity
0.44	GO:0004523	RNA-DNA hybrid ribonuclease activity
0.43	GO:0003964	RNA-directed DNA polymerase activity
0.43	GO:0004175	endopeptidase activity
0.39	GO:0003887	DNA-directed DNA polymerase activity
0.37	GO:0004170	dUTP diphosphatase activity
0.33	GO:0005515	protein binding

0.66	GO:0019028	viral capsid
0.46	GO:0005886	plasma membrane
0.37	GO:0036338	viral membrane
0.35	GO:0030430	host cell cytoplasm
0.34	GO:0042025	host cell nucleus
0.30	GO:0016021	integral component of membrane

0.44	EC:3.1.26.4	GO:0004523
0.37	KEGG:R02100	GO:0004170

sp|P63146|UBE2B_HUMAN
Ubiquitin-conjugating enzyme E2 B
Search

UBE2B

0.62	Ubiquitin-conjugating enzyme

0.55	GO:0070979	protein K11-linked ubiquitination
0.55	GO:0033522	histone H2A ubiquitination
0.55	GO:0070936	protein K48-linked ubiquitination
0.54	GO:0033128	negative regulation of histone phosphorylation
0.54	GO:0051865	protein autoubiquitination
0.54	GO:0043951	negative regulation of cAMP-mediated signaling
0.54	GO:0006344	maintenance of chromatin silencing
0.53	GO:0010845	positive regulation of reciprocal meiotic recombination
0.53	GO:0007288	sperm axoneme assembly
0.53	GO:0051026	chiasma assembly

0.55	GO:0061631	ubiquitin conjugating enzyme activity
0.54	GO:0031625	ubiquitin protein ligase binding
0.53	GO:0030554	adenyl nucleotide binding
0.52	GO:0097367	carbohydrate derivative binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0061630	ubiquitin protein ligase activity
0.34	GO:0043130	ubiquitin binding

0.58	GO:0033503	HULC complex
0.54	GO:0001741	XY body
0.50	GO:0000790	nuclear chromatin
0.47	GO:0005657	replication fork
0.39	GO:0005737	cytoplasm
0.35	GO:0005886	plasma membrane
0.35	GO:0005654	nucleoplasm
0.30	GO:0016021	integral component of membrane

sp|P63151|2ABA_HUMAN
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform
Search

PPP2R2A

0.66	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B

0.78	GO:0043666	regulation of phosphoprotein phosphatase activity
0.55	GO:0043278	response to morphine
0.49	GO:0006470	protein dephosphorylation
0.45	GO:0072554	blood vessel lumenization
0.44	GO:0000278	mitotic cell cycle
0.35	GO:0031468	nuclear envelope reassembly
0.35	GO:0044839	cell cycle G2/M phase transition
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0043065	positive regulation of apoptotic process

0.79	GO:0019888	protein phosphatase regulator activity
0.51	GO:0004722	protein serine/threonine phosphatase activity
0.40	GO:0048156	tau protein binding
0.39	GO:0051721	protein phosphatase 2A binding
0.37	GO:0032403	protein complex binding

0.80	GO:0000159	protein phosphatase type 2A complex
0.42	GO:0005829	cytosol
0.33	GO:0005654	nucleoplasm
0.33	GO:0005740	mitochondrial envelope
0.30	GO:0031224	intrinsic component of membrane

sp|P63162|RSMN_HUMAN
Small nuclear ribonucleoprotein-associated protein N
Search

SNRPN

0.86	Small nuclear ribonucleoprotein-associated protein B'

0.50	GO:0000398	mRNA splicing, via spliceosome
0.43	GO:0022618	ribonucleoprotein complex assembly
0.41	GO:0008213	protein alkylation
0.40	GO:0043414	macromolecule methylation
0.38	GO:0009725	response to hormone
0.34	GO:0007420	brain development
0.33	GO:0008334	histone mRNA metabolic process
0.32	GO:0006369	termination of RNA polymerase II transcription
0.32	GO:0051170	nuclear import

0.57	GO:0003723	RNA binding
0.36	GO:1990447	U2 snRNP binding
0.36	GO:1990446	U1 snRNP binding
0.34	GO:0005515	protein binding

0.60	GO:0030529	intracellular ribonucleoprotein complex
0.59	GO:0005634	nucleus
0.57	GO:0019013	viral nucleocapsid
0.51	GO:0120114	Sm-like protein family complex
0.47	GO:0031974	membrane-enclosed lumen
0.47	GO:0034709	methylosome
0.45	GO:0044446	intracellular organelle part
0.41	GO:0005829	cytosol
0.39	GO:0043234	protein complex
0.35	GO:0070062	extracellular exosome

sp|P63165|SUMO1_HUMAN
Small ubiquitin-related modifier 1
Search

SUMO1

0.76	Small ubiquitin-related modifier

0.79	GO:0016925	protein sumoylation
0.52	GO:1902260	negative regulation of delayed rectifier potassium channel activity
0.52	GO:0045759	negative regulation of action potential
0.51	GO:0090204	protein localization to nuclear pore
0.51	GO:0030578	PML body organization
0.51	GO:0071276	cellular response to cadmium ion
0.51	GO:1901896	positive regulation of calcium-transporting ATPase activity
0.50	GO:0060021	palate development
0.49	GO:0086004	regulation of cardiac muscle cell contraction
0.49	GO:0034605	cellular response to heat

0.61	GO:0008134	transcription factor binding
0.50	GO:0015459	potassium channel regulator activity
0.50	GO:0044388	small protein activating enzyme binding
0.48	GO:0031386	protein tag
0.47	GO:0031625	ubiquitin protein ligase binding
0.47	GO:0008022	protein C-terminus binding
0.47	GO:0051427	hormone receptor binding
0.46	GO:0030674	protein binding, bridging
0.38	GO:0019789	SUMO transferase activity
0.34	GO:0003723	RNA binding

0.59	GO:0005634	nucleus
0.48	GO:0035770	ribonucleoprotein granule
0.47	GO:0001741	XY body
0.47	GO:0008076	voltage-gated potassium channel complex
0.44	GO:0070013	intracellular organelle lumen
0.44	GO:0012505	endomembrane system
0.42	GO:0031967	organelle envelope
0.41	GO:0031090	organelle membrane
0.40	GO:1902494	catalytic complex
0.39	GO:0000792	heterochromatin

0.32

GO:0016491

sp|P63167|DYL1_HUMAN
Dynein light chain 1, cytoplasmic
Search

DYNLL1

0.89	Cytoplasmic light-chain dynein

0.72	GO:0007017	microtubule-based process
0.51	GO:0030705	cytoskeleton-dependent intracellular transport
0.51	GO:2000582	positive regulation of ATP-dependent microtubule motor activity, plus-end-directed
0.51	GO:0060271	cilium assembly
0.48	GO:1902857	positive regulation of non-motile cilium assembly
0.46	GO:0006928	movement of cell or subcellular component
0.46	GO:0042326	negative regulation of phosphorylation
0.45	GO:0031503	protein complex localization
0.41	GO:0006886	intracellular protein transport
0.38	GO:0006915	apoptotic process

0.53	GO:0045505	dynein intermediate chain binding
0.50	GO:0051959	dynein light intermediate chain binding
0.50	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed
0.45	GO:0008022	protein C-terminus binding
0.45	GO:0008092	cytoskeletal protein binding
0.44	GO:0019904	protein domain specific binding
0.39	GO:0097110	scaffold protein binding
0.39	GO:0030235	nitric-oxide synthase regulator activity
0.37	GO:0042803	protein homodimerization activity
0.37	GO:0046982	protein heterodimerization activity

0.79	GO:0030286	dynein complex
0.50	GO:0005813	centrosome
0.48	GO:0072686	mitotic spindle
0.48	GO:0008180	COP9 signalosome
0.48	GO:0000776	kinetochore
0.45	GO:0005929	cilium
0.44	GO:0031475	myosin V complex
0.41	GO:0005829	cytosol
0.39	GO:0005874	microtubule
0.38	GO:1904115	axon cytoplasm

0.50

EC:3.6.4.4

GO:0008574

sp|P63172|DYLT1_HUMAN
Dynein light chain Tctex-type 1
Search

DYNLT1

0.93	Dynein light chain Tctex-type 1

0.85	GO:0019060	intracellular transport of viral protein in host cell
0.50	GO:0000132	establishment of mitotic spindle orientation
0.49	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.49	GO:0050768	negative regulation of neurogenesis
0.46	GO:0010976	positive regulation of neuron projection development
0.46	GO:0048468	cell development
0.46	GO:1905709	negative regulation of membrane permeability
0.46	GO:0008090	retrograde axonal transport
0.46	GO:0035022	positive regulation of Rac protein signal transduction
0.45	GO:0008340	determination of adult lifespan

0.73	GO:0042802	identical protein binding
0.46	GO:0003774	motor activity
0.45	GO:0051959	dynein light intermediate chain binding
0.45	GO:0097718	disordered domain specific binding
0.45	GO:0045505	dynein intermediate chain binding
0.44	GO:0008022	protein C-terminus binding
0.41	GO:0031681	G-protein beta-subunit binding
0.41	GO:0030742	GTP-dependent protein binding
0.40	GO:0046983	protein dimerization activity
0.35	GO:0042623	ATPase activity, coupled

0.82	GO:0005868	cytoplasmic dynein complex
0.81	GO:0005881	cytoplasmic microtubule
0.77	GO:0099503	secretory vesicle
0.61	GO:0044216	other organism cell
0.61	GO:0018995	host
0.49	GO:0033267	axon part
0.47	GO:0030426	growth cone
0.47	GO:0005819	spindle
0.46	GO:0044297	cell body
0.45	GO:0120111	neuron projection cytoplasm

sp|P63173|RL38_HUMAN
60S ribosomal protein L38
Search

RPL38

0.80	Ribosomal protein rpl38

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.48	GO:0022618	ribonucleoprotein complex assembly
0.47	GO:0048318	axial mesoderm development
0.47	GO:0009790	embryo development
0.45	GO:0001503	ossification
0.45	GO:0043583	ear development
0.45	GO:0007605	sensory perception of sound

0.64	GO:0003735	structural constituent of ribosome
0.40	GO:0003723	RNA binding
0.33	GO:0008168	methyltransferase activity

0.61	GO:0005840	ribosome
0.49	GO:0033291	eukaryotic 80S initiation complex
0.47	GO:0044445	cytosolic part
0.44	GO:0005844	polysome
0.41	GO:0044446	intracellular organelle part
0.36	GO:0005925	focal adhesion
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0008168

sp|P63208|SKP1_HUMAN
S-phase kinase-associated protein 1
Search

SKP1

0.91	S-phase kinase-associated protein 1

0.70	GO:0006511	ubiquitin-dependent protein catabolic process
0.53	GO:0016310	phosphorylation
0.44	GO:0010498	proteasomal protein catabolic process
0.42	GO:0016567	protein ubiquitination
0.41	GO:0051457	maintenance of protein location in nucleus
0.38	GO:0016570	histone modification
0.36	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.36	GO:0010265	SCF complex assembly
0.36	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.36	GO:0038095	Fc-epsilon receptor signaling pathway

0.55	GO:0016301	kinase activity
0.41	GO:0097602	cullin family protein binding
0.40	GO:0008013	beta-catenin binding
0.39	GO:0019904	protein domain specific binding
0.39	GO:0061630	ubiquitin protein ligase activity
0.37	GO:0004806	triglyceride lipase activity
0.33	GO:0016874	ligase activity

0.50	GO:0031467	Cul7-RING ubiquitin ligase complex
0.48	GO:0019005	SCF ubiquitin ligase complex
0.42	GO:0005829	cytosol
0.41	GO:0005813	centrosome
0.40	GO:0031519	PcG protein complex
0.37	GO:0070062	extracellular exosome
0.36	GO:0005654	nucleoplasm

0.37

EC:3.1.1.3

GO:0004806

sp|P63211|GBG1_HUMAN
Guanine nucleotide-binding protein G(T) subunit gamma-T1
Search

0.71	Guanine nucleotide-binding protein subunit gamma

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.52	GO:0042462	eye photoreceptor cell development
0.50	GO:0007602	phototransduction
0.44	GO:0008104	protein localization
0.40	GO:0010659	cardiac muscle cell apoptotic process
0.38	GO:0071456	cellular response to hypoxia
0.35	GO:0022400	regulation of rhodopsin mediated signaling pathway
0.35	GO:0071377	cellular response to glucagon stimulus
0.35	GO:0071482	cellular response to light stimulus
0.35	GO:0009584	detection of visible light

0.64	GO:0004871	signal transducer activity
0.41	GO:0003924	GTPase activity
0.34	GO:0005515	protein binding
0.34	GO:0003995	acyl-CoA dehydrogenase activity
0.33	GO:0050660	flavin adenine dinucleotide binding

0.81	GO:1905360	GTPase complex
0.79	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.65	GO:0098797	plasma membrane protein complex
0.39	GO:0001750	photoreceptor outer segment
0.38	GO:0001917	photoreceptor inner segment
0.37	GO:0060170	ciliary membrane

0.34

EC:1.3.99.3

GO:0003995

sp|P63215|GBG3_HUMAN
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3
Search

GNG3

0.71	Guanine nucleotide-binding protein subunit gamma

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.43	GO:0008283	cell proliferation
0.42	GO:0048010	vascular endothelial growth factor receptor signaling pathway
0.42	GO:0002040	sprouting angiogenesis
0.38	GO:0007204	positive regulation of cytosolic calcium ion concentration
0.37	GO:0071377	cellular response to glucagon stimulus
0.36	GO:0071380	cellular response to prostaglandin E stimulus
0.36	GO:0071870	cellular response to catecholamine stimulus
0.36	GO:0019933	cAMP-mediated signaling
0.35	GO:0000187	activation of MAPK activity

0.64	GO:0004871	signal transducer activity
0.50	GO:0031681	G-protein beta-subunit binding
0.40	GO:0031702	type 1 angiotensin receptor binding
0.36	GO:0003924	GTPase activity

0.81	GO:1905360	GTPase complex
0.80	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.66	GO:0098797	plasma membrane protein complex
0.52	GO:0014069	postsynaptic density
0.51	GO:0030425	dendrite
0.51	GO:0044297	cell body
0.38	GO:0005829	cytosol
0.35	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

sp|P63218|GBG5_HUMAN
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
Search

GNG5

0.71	Guanine nucleotide-binding protein subunit gamma

0.71	GO:0007186	G-protein coupled receptor signaling pathway
0.51	GO:0072513	positive regulation of secondary heart field cardioblast proliferation
0.49	GO:2000179	positive regulation of neural precursor cell proliferation
0.43	GO:0030308	negative regulation of cell growth
0.37	GO:0071377	cellular response to glucagon stimulus
0.35	GO:0007368	determination of left/right symmetry
0.34	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.32	GO:0005975	carbohydrate metabolic process

0.64	GO:0004871	signal transducer activity
0.51	GO:0030165	PDZ domain binding
0.34	GO:0003924	GTPase activity
0.34	GO:0008061	chitin binding
0.33	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.81	GO:1905360	GTPase complex
0.79	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.65	GO:0098797	plasma membrane protein complex
0.41	GO:0031680	G-protein beta/gamma-subunit complex
0.41	GO:0005739	mitochondrion
0.37	GO:0070062	extracellular exosome
0.34	GO:0036064	ciliary basal body
0.34	GO:0005813	centrosome

0.33

GO:0004553

sp|P63220|RS21_HUMAN
40S ribosomal protein S21
Search

RPS21

0.70	Ribosomal protein S21

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.45	GO:0016072	rRNA metabolic process
0.44	GO:0042254	ribosome biogenesis
0.43	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.42	GO:0048542	lymph gland development
0.39	GO:0042127	regulation of cell proliferation
0.39	GO:0006417	regulation of translation

0.64	GO:0003735	structural constituent of ribosome
0.51	GO:0047485	protein N-terminus binding
0.41	GO:0043022	ribosome binding
0.34	GO:0005102	receptor binding
0.34	GO:0003723	RNA binding
0.32	GO:0016779	nucleotidyltransferase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005840	ribosome
0.52	GO:0005844	polysome
0.49	GO:0044445	cytosolic part
0.42	GO:0044446	intracellular organelle part
0.34	GO:0005791	rough endoplasmic reticulum
0.34	GO:0098562	cytoplasmic side of membrane
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0043233	organelle lumen
0.33	GO:0005634	nucleus

0.32

EC:2.7.7

GO:0016779

sp|P63241|IF5A1_HUMAN
Eukaryotic translation initiation factor 5A-1
Search

EIF5A

0.65	Eukaryotic translation initiation factor 5A

0.84	GO:0045905	positive regulation of translational termination
0.83	GO:0045901	positive regulation of translational elongation
0.83	GO:0006452	translational frameshifting
0.60	GO:0006413	translational initiation
0.49	GO:0008284	positive regulation of cell proliferation
0.47	GO:0043065	positive regulation of apoptotic process
0.43	GO:0051028	mRNA transport
0.40	GO:0006611	protein export from nucleus
0.39	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.38	GO:0006915	apoptotic process

0.74	GO:0043022	ribosome binding
0.70	GO:0003746	translation elongation factor activity
0.61	GO:0003743	translation initiation factor activity
0.40	GO:0017070	U6 snRNA binding
0.40	GO:0047485	protein N-terminus binding
0.33	GO:0003735	structural constituent of ribosome

0.43	GO:0043231	intracellular membrane-bounded organelle
0.41	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.40	GO:0031984	organelle subcompartment
0.39	GO:0031967	organelle envelope
0.39	GO:0098589	membrane region
0.38	GO:0043234	protein complex
0.38	GO:0005737	cytoplasm
0.36	GO:0043025	neuronal cell body
0.36	GO:0070062	extracellular exosome
0.36	GO:0030425	dendrite

sp|P63244|RACK1_HUMAN
Receptor of activated protein C kinase 1
Search

0.82	Guanine nucleotide-binding protein beta subunit

0.70	GO:0033123	positive regulation of purine nucleotide catabolic process
0.70	GO:0030807	positive regulation of cyclic nucleotide catabolic process
0.70	GO:1903208	negative regulation of hydrogen peroxide-induced neuron death
0.69	GO:0030820	regulation of cAMP catabolic process
0.69	GO:0051343	positive regulation of cyclic-nucleotide phosphodiesterase activity
0.67	GO:0032464	positive regulation of protein homooligomerization
0.67	GO:0051901	positive regulation of mitochondrial depolarization
0.66	GO:0050765	negative regulation of phagocytosis
0.66	GO:2000543	positive regulation of gastrulation
0.66	GO:0042998	positive regulation of Golgi to plasma membrane protein transport

0.68	GO:0030292	protein tyrosine kinase inhibitor activity
0.66	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process
0.65	GO:0042169	SH2 domain binding
0.65	GO:0005080	protein kinase C binding
0.64	GO:0030971	receptor tyrosine kinase binding
0.62	GO:0035591	signaling adaptor activity
0.62	GO:0019903	protein phosphatase binding
0.61	GO:0030332	cyclin binding
0.60	GO:0045296	cadherin binding
0.57	GO:0043022	ribosome binding

0.68	GO:1990630	IRE1-RACK1-PP2A complex
0.65	GO:0001891	phagocytic cup
0.62	GO:0030496	midbody
0.60	GO:0048471	perinuclear region of cytoplasm
0.57	GO:0005654	nucleoplasm
0.56	GO:0043025	neuronal cell body
0.56	GO:0005829	cytosol
0.54	GO:0030425	dendrite
0.48	GO:0005739	mitochondrion
0.44	GO:0070062	extracellular exosome

sp|P63252|KCNJ2_HUMAN
Inward rectifier potassium channel 2
Search

KCNJ2

0.86	Inward rectifier potassium channel

0.78	GO:0034765	regulation of ion transmembrane transport
0.71	GO:0006813	potassium ion transport
0.63	GO:0014861	regulation of skeletal muscle contraction via regulation of action potential
0.62	GO:0090076	relaxation of skeletal muscle
0.61	GO:0098655	cation transmembrane transport
0.61	GO:0055119	relaxation of cardiac muscle
0.60	GO:0086013	membrane repolarization during cardiac muscle cell action potential
0.59	GO:0086002	cardiac muscle cell action potential involved in contraction
0.59	GO:0086091	regulation of heart rate by cardiac conduction
0.58	GO:0051289	protein homotetramerization

0.84	GO:0005242	inward rectifier potassium channel activity
0.60	GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization
0.57	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.51	GO:0042802	identical protein binding

0.54	GO:0008076	voltage-gated potassium channel complex
0.40	GO:0005790	smooth endoplasmic reticulum
0.39	GO:0030315	T-tubule
0.39	GO:0014704	intercalated disc
0.39	GO:0043197	dendritic spine
0.38	GO:0005791	rough endoplasmic reticulum
0.38	GO:0043025	neuronal cell body
0.37	GO:0005794	Golgi apparatus

sp|P63261|ACTG_HUMAN
Actin, cytoplasmic 2
Search

ACTB

0.63	Actin cytoplasmic 1

0.53	GO:0098974	postsynaptic actin cytoskeleton organization
0.52	GO:0072749	cellular response to cytochalasin B
0.49	GO:0032091	negative regulation of protein binding
0.46	GO:0045214	sarcomere organization
0.46	GO:0071346	cellular response to interferon-gamma
0.44	GO:0048870	cell motility
0.39	GO:0070527	platelet aggregation
0.39	GO:0001895	retina homeostasis
0.37	GO:0021762	substantia nigra development
0.37	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis

0.53	GO:0098973	structural constituent of postsynaptic actin cytoskeleton
0.51	GO:0030554	adenyl nucleotide binding
0.51	GO:0030957	Tat protein binding
0.51	GO:0050998	nitric-oxide synthase binding
0.51	GO:0097367	carbohydrate derivative binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0008144	drug binding
0.50	GO:0042802	identical protein binding
0.49	GO:0019894	kinesin binding
0.49	GO:0005522	profilin binding

0.76	GO:0097433	dense body
0.70	GO:0005925	focal adhesion
0.61	GO:0005856	cytoskeleton
0.53	GO:0043209	myelin sheath
0.50	GO:0005886	plasma membrane
0.47	GO:0035267	NuA4 histone acetyltransferase complex
0.47	GO:0036464	cytoplasmic ribonucleoprotein granule
0.47	GO:0070062	extracellular exosome
0.46	GO:0044448	cell cortex part
0.45	GO:0005829	cytosol

sp|P63267|ACTH_HUMAN
Actin, gamma-enteric smooth muscle
Search

ACTG2

0.96	Smooth muscle alpha actin

0.81	GO:0090131	mesenchyme migration
0.65	GO:0010628	positive regulation of gene expression
0.42	GO:0072144	glomerular mesangial cell development
0.42	GO:0006936	muscle contraction
0.41	GO:0008015	blood circulation
0.39	GO:0009615	response to virus
0.39	GO:0003015	heart process
0.38	GO:0035296	regulation of tube diameter
0.38	GO:0003018	vascular process in circulatory system
0.38	GO:0061869	regulation of hepatic stellate cell migration

0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0019901	protein kinase binding
0.35	GO:0005200	structural constituent of cytoskeleton

0.75	GO:0030175	filopodium
0.74	GO:0030027	lamellipodium
0.72	GO:0044297	cell body
0.54	GO:0032982	myosin filament
0.46	GO:0005737	cytoplasm
0.41	GO:0070062	extracellular exosome
0.39	GO:0072562	blood microparticle
0.39	GO:0097517	contractile actin filament bundle
0.39	GO:0042641	actomyosin
0.38	GO:0071944	cell periphery

sp|P63272|SPT4H_HUMAN
Transcription elongation factor SPT4
Search

SUPT4H1

0.68	Transcription elongation factor SPT4-A

0.81	GO:0032786	positive regulation of DNA-templated transcription, elongation
0.58	GO:0006414	translational elongation
0.55	GO:0006351	transcription, DNA-templated
0.54	GO:0032785	negative regulation of DNA-templated transcription, elongation
0.54	GO:0034243	regulation of transcription elongation from RNA polymerase II promoter
0.50	GO:0000122	negative regulation of transcription by RNA polymerase II
0.48	GO:0045944	positive regulation of transcription by RNA polymerase II
0.44	GO:0006325	chromatin organization
0.43	GO:0006397	mRNA processing
0.34	GO:0050434	positive regulation of viral transcription

0.63	GO:0008270	zinc ion binding
0.59	GO:0003746	translation elongation factor activity
0.49	GO:0000993	RNA polymerase II core binding
0.48	GO:0046982	protein heterodimerization activity
0.47	GO:0003727	single-stranded RNA binding
0.41	GO:0003700	DNA binding transcription factor activity

0.61	GO:0005634	nucleus
0.48	GO:0031974	membrane-enclosed lumen
0.44	GO:0043234	protein complex
0.43	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|P63279|UBC9_HUMAN
SUMO-conjugating enzyme UBC9
Search

UBE2I

0.76	SUMO-conjugating enzyme UBC9-B

0.80	GO:0016925	protein sumoylation
0.48	GO:1903755	positive regulation of SUMO transferase activity
0.46	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.45	GO:0000122	negative regulation of transcription by RNA polymerase II
0.44	GO:0007059	chromosome segregation
0.42	GO:0051301	cell division
0.42	GO:0007049	cell cycle
0.38	GO:0060216	definitive hemopoiesis
0.36	GO:0042359	vitamin D metabolic process
0.36	GO:0061484	hematopoietic stem cell homeostasis

0.82	GO:0019789	SUMO transferase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0043398	HLH domain binding
0.48	GO:0071535	RING-like zinc finger domain binding
0.47	GO:0044388	small protein activating enzyme binding
0.46	GO:0061650	ubiquitin-like protein conjugating enzyme activity
0.44	GO:0031625	ubiquitin protein ligase binding
0.43	GO:0061630	ubiquitin protein ligase activity

0.48	GO:1990356	sumoylated E2 ligase complex
0.45	GO:0016605	PML body
0.41	GO:0005829	cytosol
0.41	GO:1990234	transferase complex
0.37	GO:0005635	nuclear envelope
0.36	GO:0000795	synaptonemal complex
0.36	GO:0001650	fibrillar center
0.35	GO:0030425	dendrite
0.35	GO:0045202	synapse

0.35

GO:0016874

sp|P63302|SELW_HUMAN
Selenoprotein W
Search

SELENOW

0.96	LOW QUALITY PROTEIN: selenoprotein W

0.63	GO:0098869	cellular oxidant detoxification
0.49	GO:0010269	response to selenium ion
0.45	GO:0006884	cell volume homeostasis
0.44	GO:0000387	spliceosomal snRNP assembly
0.43	GO:0006821	chloride transport
0.41	GO:0007219	Notch signaling pathway
0.40	GO:0055114	oxidation-reduction process
0.38	GO:0007275	multicellular organism development

0.63	GO:0016209	antioxidant activity
0.42	GO:0003954	NADH dehydrogenase activity
0.40	GO:0004089	carbonate dehydratase activity
0.39	GO:0005509	calcium ion binding

0.46	GO:0005737	cytoplasm
0.43	GO:0120114	Sm-like protein family complex
0.43	GO:0034708	methyltransferase complex
0.40	GO:0005886	plasma membrane
0.38	GO:0043231	intracellular membrane-bounded organelle
0.38	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.42

EC:1.6.99.3

GO:0003954

sp|P63313|TYB10_HUMAN
Thymosin beta-10
Search

0.94	thymosin beta-b

0.75	GO:0007015	actin filament organization
0.47	GO:1905271	regulation of proton-transporting ATP synthase activity, rotational mechanism
0.46	GO:0042989	sequestering of actin monomers
0.46	GO:0007253	cytoplasmic sequestering of NF-kappaB
0.45	GO:2000483	negative regulation of interleukin-8 secretion
0.45	GO:2001171	positive regulation of ATP biosynthetic process
0.45	GO:1901223	negative regulation of NIK/NF-kappaB signaling
0.45	GO:2001028	positive regulation of endothelial cell chemotaxis
0.45	GO:1903026	negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding
0.44	GO:0043536	positive regulation of blood vessel endothelial cell migration

0.85	GO:0003785	actin monomer binding
0.41	GO:0019899	enzyme binding
0.35	GO:0003727	single-stranded RNA binding
0.34	GO:0004888	transmembrane signaling receptor activity

0.43	GO:0005856	cytoskeleton
0.41	GO:0005829	cytosol
0.40	GO:0005576	extracellular region
0.39	GO:0005634	nucleus
0.35	GO:0031093	platelet alpha granule lumen
0.30	GO:0044425	membrane part

sp|P63316|TNNC1_HUMAN
Troponin C, slow skeletal and cardiac muscles
Search

TNNC1

0.94	Troponin C, slow skeletal and cardiac muscles

0.61	GO:0006941	striated muscle contraction
0.60	GO:0060047	heart contraction
0.59	GO:0032972	regulation of muscle filament sliding speed
0.58	GO:0003231	cardiac ventricle development
0.58	GO:0014883	transition between fast and slow fiber
0.56	GO:0003229	ventricular cardiac muscle tissue development
0.56	GO:0055008	cardiac muscle tissue morphogenesis
0.55	GO:0003206	cardiac chamber morphogenesis
0.52	GO:0043462	regulation of ATPase activity
0.49	GO:0050881	musculoskeletal movement

0.69	GO:0005509	calcium ion binding
0.59	GO:0031014	troponin T binding
0.59	GO:0031013	troponin I binding
0.58	GO:0048306	calcium-dependent protein binding
0.53	GO:0051015	actin filament binding
0.51	GO:0042803	protein homodimerization activity

0.59	GO:1990584	cardiac Troponin complex
0.35	GO:0097512	cardiac myofibril
0.33	GO:0005829	cytosol

sp|P67775|PP2AA_HUMAN
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
Search

PPP2CA

0.47	Serine/threonine-protein phosphatase

0.72	GO:0006470	protein dephosphorylation
0.52	GO:0010719	negative regulation of epithelial to mesenchymal transition
0.51	GO:0007498	mesoderm development
0.51	GO:0008637	apoptotic mitochondrial changes
0.50	GO:0042542	response to hydrogen peroxide
0.49	GO:0071902	positive regulation of protein serine/threonine kinase activity
0.48	GO:0034976	response to endoplasmic reticulum stress
0.47	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.46	GO:0046677	response to antibiotic
0.42	GO:1904528	positive regulation of microtubule binding

0.72	GO:0004721	phosphoprotein phosphatase activity
0.53	GO:0050811	GABA receptor binding
0.52	GO:0008022	protein C-terminus binding
0.49	GO:0046982	protein heterodimerization activity
0.37	GO:0046872	metal ion binding
0.35	GO:1990405	protein antigen binding
0.35	GO:0031698	beta-2 adrenergic receptor binding
0.35	GO:0048156	tau protein binding
0.35	GO:0043422	protein kinase B binding
0.35	GO:0051721	protein phosphatase 2A binding

0.57	GO:0000159	protein phosphatase type 2A complex
0.50	GO:0000775	chromosome, centromeric region
0.45	GO:0005829	cytosol
0.43	GO:0000922	spindle pole
0.40	GO:0005886	plasma membrane
0.39	GO:0005634	nucleus
0.38	GO:0070062	extracellular exosome
0.35	GO:0043195	terminal bouton
0.34	GO:0014069	postsynaptic density
0.33	GO:0005739	mitochondrion

0.72

GO:0004721

sp|P67809|YBOX1_HUMAN
Nuclease-sensitive element-binding protein 1
Search

YBX1

0.92	TSH receptor suppressor element-binding protein-1

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.52	GO:1903608	protein localization to cytoplasmic stress granule
0.51	GO:1902369	negative regulation of RNA catabolic process
0.50	GO:0051154	negative regulation of striated muscle cell differentiation
0.48	GO:1903312	negative regulation of mRNA metabolic process
0.46	GO:0001701	in utero embryonic development
0.46	GO:0006366	transcription by RNA polymerase II
0.45	GO:1902680	positive regulation of RNA biosynthetic process

0.54	GO:0003677	DNA binding
0.48	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.46	GO:0001067	regulatory region nucleic acid binding
0.46	GO:0003682	chromatin binding
0.45	GO:0051020	GTPase binding
0.42	GO:0003723	RNA binding
0.37	GO:0008190	eukaryotic initiation factor 4E binding
0.36	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.35	GO:0002039	p53 binding
0.34	GO:0008134	transcription factor binding

0.54	GO:0071204	histone pre-mRNA 3'end processing complex
0.52	GO:0070937	CRD-mediated mRNA stability complex
0.50	GO:0005689	U12-type spliceosomal complex
0.49	GO:0010494	cytoplasmic stress granule
0.47	GO:0031965	nuclear membrane
0.43	GO:0005829	cytosol
0.38	GO:0005576	extracellular region
0.35	GO:1990124	messenger ribonucleoprotein complex
0.35	GO:0031982	vesicle
0.35	GO:0043025	neuronal cell body

0.36

GO:0003755

sp|P67812|SC11A_HUMAN
Signal peptidase complex catalytic subunit SEC11A
Search

SEC11A

0.72	Signal peptidase complex catalytic subunit SEC11

0.80

GO:0006465

signal peptide processing

0.67

GO:0008236

serine-type peptidase activity

0.82	GO:0005787	signal peptidase complex
0.38	GO:0031090	organelle membrane
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

sp|P67870|CSK2B_HUMAN
Casein kinase II subunit beta
Search

CSNK2B

0.59	Casein kinase II subunit beta

0.76	GO:0045859	regulation of protein kinase activity
0.54	GO:0033211	adiponectin-activated signaling pathway
0.53	GO:0032927	positive regulation of activin receptor signaling pathway
0.53	GO:0061154	endothelial tube morphogenesis
0.52	GO:0043537	negative regulation of blood vessel endothelial cell migration
0.52	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
0.51	GO:0018107	peptidyl-threonine phosphorylation
0.41	GO:0016055	Wnt signaling pathway
0.38	GO:0097421	liver regeneration
0.38	GO:0033574	response to testosterone

0.79	GO:0019887	protein kinase regulator activity
0.52	GO:0016301	kinase activity
0.48	GO:0003682	chromatin binding
0.48	GO:0019904	protein domain specific binding
0.47	GO:0042802	identical protein binding
0.46	GO:0008134	transcription factor binding
0.46	GO:0005102	receptor binding
0.42	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.41	GO:0140096	catalytic activity, acting on a protein
0.36	GO:0043021	ribonucleoprotein complex binding

0.83	GO:0005956	protein kinase CK2 complex
0.52	GO:0031519	PcG protein complex
0.40	GO:0005886	plasma membrane
0.37	GO:0016363	nuclear matrix
0.37	GO:0005737	cytoplasm
0.36	GO:0005929	cilium
0.36	GO:0000785	chromatin
0.36	GO:0070062	extracellular exosome
0.35	GO:0031983	vesicle lumen
0.34	GO:0097708	intracellular vesicle

0.42

GO:0016773

sp|P67936|TPM4_HUMAN
Tropomyosin alpha-4 chain
Search

TPM4

0.84	Cytoskeletal tropomyosin

0.70	GO:0006936	muscle contraction
0.63	GO:0097435	supramolecular fiber organization
0.63	GO:0030036	actin cytoskeleton organization
0.56	GO:0055013	cardiac muscle cell development
0.55	GO:0060047	heart contraction
0.53	GO:0010927	cellular component assembly involved in morphogenesis
0.49	GO:0070925	organelle assembly
0.44	GO:0001649	osteoblast differentiation
0.41	GO:0033275	actin-myosin filament sliding

0.68	GO:0008307	structural constituent of muscle
0.61	GO:0051015	actin filament binding
0.47	GO:0042803	protein homodimerization activity
0.47	GO:0046982	protein heterodimerization activity
0.39	GO:0046872	metal ion binding
0.36	GO:0003924	GTPase activity
0.36	GO:0032550	purine ribonucleoside binding
0.36	GO:0019001	guanyl nucleotide binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.72	GO:0005884	actin filament
0.71	GO:0097517	contractile actin filament bundle
0.71	GO:0042641	actomyosin
0.70	GO:0005862	muscle thin filament tropomyosin
0.66	GO:0002102	podosome
0.62	GO:0030863	cortical cytoskeleton
0.43	GO:0005925	focal adhesion
0.43	GO:0070062	extracellular exosome
0.37	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|P68032|ACTC_HUMAN
Actin, alpha cardiac muscle 1
Search

ACTC1

0.83	Actin aortic smooth muscle

0.78	GO:0090131	mesenchyme migration
0.63	GO:0010628	positive regulation of gene expression
0.57	GO:0030240	skeletal muscle thin filament assembly
0.56	GO:0033275	actin-myosin filament sliding
0.55	GO:0055003	cardiac myofibril assembly
0.54	GO:0055008	cardiac muscle tissue morphogenesis
0.54	GO:0060047	heart contraction
0.50	GO:0043066	negative regulation of apoptotic process
0.43	GO:0006936	muscle contraction
0.43	GO:0072144	glomerular mesangial cell development

0.53	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0017022	myosin binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0016887	ATPase activity
0.40	GO:0019901	protein kinase binding
0.34	GO:0005200	structural constituent of cytoskeleton

0.73	GO:0030175	filopodium
0.71	GO:0030027	lamellipodium
0.69	GO:0044297	cell body
0.56	GO:0042643	actomyosin, actin portion
0.54	GO:0044449	contractile fiber part
0.52	GO:0030016	myofibril
0.38	GO:0097517	contractile actin filament bundle
0.38	GO:0070062	extracellular exosome
0.37	GO:0043234	protein complex
0.36	GO:0072562	blood microparticle

0.43

GO:0016887

sp|P68036|UB2L3_HUMAN
Ubiquitin-conjugating enzyme E2 L3
Search

UBE2L3

0.93	Ubiquitin conjugating enzyme E2 L5, pseudogene

0.50	GO:0070979	protein K11-linked ubiquitination
0.50	GO:0071385	cellular response to glucocorticoid stimulus
0.49	GO:1903955	positive regulation of protein targeting to mitochondrion
0.49	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.48	GO:0044770	cell cycle phase transition
0.48	GO:0051443	positive regulation of ubiquitin-protein transferase activity
0.47	GO:0008283	cell proliferation
0.40	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.40	GO:1903506	regulation of nucleic acid-templated transcription
0.39	GO:0010468	regulation of gene expression

0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0061631	ubiquitin conjugating enzyme activity
0.48	GO:0097027	ubiquitin-protein transferase activator activity
0.47	GO:0003713	transcription coactivator activity
0.46	GO:0031625	ubiquitin protein ligase binding
0.33	GO:0003723	RNA binding
0.33	GO:0016874	ligase activity
0.33	GO:0003924	GTPase activity

0.41	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.34	GO:0098793	presynapse
0.34	GO:0000151	ubiquitin ligase complex
0.33	GO:0043233	organelle lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.33

GO:0016874

sp|P68104|EF1A1_HUMAN
Elongation factor 1-alpha 1
Search

EEF1A1

0.45	Translation elongation factor EF-1 subunit alpha

0.68	GO:0006414	translational elongation
0.51	GO:0071364	cellular response to epidermal growth factor stimulus
0.35	GO:1904714	regulation of chaperone-mediated autophagy
0.35	GO:1903427	negative regulation of reactive oxygen species biosynthetic process
0.35	GO:1990090	cellular response to nerve growth factor stimulus
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0010976	positive regulation of neuron projection development
0.34	GO:0035690	cellular response to drug
0.34	GO:0007568	aging
0.34	GO:0010942	positive regulation of cell death

0.69	GO:0003746	translation elongation factor activity
0.66	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0032561	guanyl ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.46	GO:0019901	protein kinase binding
0.46	GO:0005516	calmodulin binding
0.43	GO:0000049	tRNA binding
0.34	GO:0003729	mRNA binding
0.32	GO:0008144	drug binding

0.49	GO:0032587	ruffle membrane
0.48	GO:0005737	cytoplasm
0.47	GO:0043209	myelin sheath
0.46	GO:0005730	nucleolus
0.45	GO:0015629	actin cytoskeleton
0.43	GO:0044430	cytoskeletal part
0.37	GO:0070062	extracellular exosome
0.35	GO:0031983	vesicle lumen
0.34	GO:0098562	cytoplasmic side of membrane
0.34	GO:0097708	intracellular vesicle

sp|P68106|FKB1B_HUMAN
Peptidyl-prolyl cis-trans isomerase FKBP1B
Search

FKBP1B

0.61	Peptidyl-prolyl cis-trans isomerase FKBP1B

0.85	GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
0.85	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity
0.84	GO:0033197	response to vitamin E
0.83	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus
0.82	GO:0014808	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
0.82	GO:0098870	action potential propagation
0.81	GO:0010459	negative regulation of heart rate
0.81	GO:0051280	negative regulation of release of sequestered calcium ion into cytosol
0.81	GO:0048680	positive regulation of axon regeneration
0.81	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling

0.81	GO:0019855	calcium channel inhibitor activity
0.77	GO:0005528	FK506 binding
0.76	GO:0044325	ion channel binding
0.70	GO:0030551	cyclic nucleotide binding
0.70	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.66	GO:0005102	receptor binding
0.54	GO:0005219	ryanodine-sensitive calcium-release channel activity

0.82	GO:0016529	sarcoplasmic reticulum
0.75	GO:0030018	Z disc
0.72	GO:0034704	calcium channel complex
0.69	GO:0098827	endoplasmic reticulum subcompartment
0.65	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.64	GO:0098588	bounding membrane of organelle
0.46	GO:0005829	cytosol

0.70

GO:0003755

sp|P68133|ACTS_HUMAN
Actin, alpha skeletal muscle
Search

0.84	Actin alpha skeletal muscle

0.69	GO:0090131	mesenchyme migration
0.59	GO:0030240	skeletal muscle thin filament assembly
0.57	GO:0010628	positive regulation of gene expression
0.54	GO:0014706	striated muscle tissue development
0.54	GO:0007517	muscle organ development
0.51	GO:0014904	myotube cell development
0.50	GO:0048747	muscle fiber development
0.49	GO:0033275	actin-myosin filament sliding
0.47	GO:0055006	cardiac cell development
0.46	GO:0060047	heart contraction

0.52	GO:0032559	adenyl ribonucleotide binding
0.51	GO:0008144	drug binding
0.51	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0017022	myosin binding
0.39	GO:0016887	ATPase activity
0.35	GO:0031013	troponin I binding
0.35	GO:0031432	titin binding
0.35	GO:0048306	calcium-dependent protein binding
0.35	GO:0005523	tropomyosin binding
0.34	GO:0003785	actin monomer binding

0.65	GO:0030175	filopodium
0.64	GO:0030027	lamellipodium
0.62	GO:0044297	cell body
0.56	GO:0042641	actomyosin
0.55	GO:0005884	actin filament
0.54	GO:0030017	sarcomere
0.51	GO:0097517	contractile actin filament bundle
0.50	GO:0036379	myofilament
0.38	GO:0072562	blood microparticle
0.37	GO:0070062	extracellular exosome

0.39

GO:0016887

sp|P68363|TBA1B_HUMAN
Tubulin alpha-1B chain
Search

0.53	Tubulin alpha chain

0.71	GO:0007017	microtubule-based process
0.71	GO:0007010	cytoskeleton organization
0.45	GO:0071353	cellular response to interleukin-4
0.36	GO:0030705	cytoskeleton-dependent intracellular transport
0.35	GO:0021634	optic nerve formation
0.35	GO:0097711	ciliary basal body-plasma membrane docking
0.35	GO:0000086	G2/M transition of mitotic cell cycle
0.34	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.34	GO:0018410	C-terminal protein amino acid modification
0.34	GO:0051301	cell division

0.77	GO:0005200	structural constituent of cytoskeleton
0.67	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0032561	guanyl ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0031625	ubiquitin protein ligase binding
0.43	GO:0003725	double-stranded RNA binding
0.36	GO:0019904	protein domain specific binding
0.34	GO:0046982	protein heterodimerization activity
0.33	GO:0046872	metal ion binding

0.73	GO:0005874	microtubule
0.48	GO:0043209	myelin sheath
0.48	GO:0005737	cytoplasm
0.43	GO:0035770	ribonucleoprotein granule
0.42	GO:0031982	vesicle
0.40	GO:0012505	endomembrane system
0.39	GO:0045121	membrane raft
0.38	GO:0043230	extracellular organelle
0.37	GO:0005615	extracellular space
0.34	GO:0030496	midbody

sp|P68366|TBA4A_HUMAN
Tubulin alpha-4A chain
Search

TUBA4A

0.53	Tubulin alpha chain

0.71	GO:0007017	microtubule-based process
0.70	GO:0007010	cytoskeleton organization
0.44	GO:0071353	cellular response to interleukin-4
0.35	GO:0097711	ciliary basal body-plasma membrane docking
0.35	GO:0002576	platelet degranulation
0.35	GO:0000086	G2/M transition of mitotic cell cycle
0.34	GO:0021782	glial cell development
0.34	GO:0042552	myelination
0.34	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.34	GO:0018410	C-terminal protein amino acid modification

0.76	GO:0005200	structural constituent of cytoskeleton
0.67	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0019899	enzyme binding
0.42	GO:0003725	double-stranded RNA binding
0.32	GO:0046872	metal ion binding

0.72	GO:0005874	microtubule
0.47	GO:0005737	cytoplasm
0.42	GO:0043209	myelin sheath
0.38	GO:0070062	extracellular exosome
0.37	GO:0045121	membrane raft
0.34	GO:0030496	midbody

sp|P68371|TBB4B_HUMAN
Tubulin beta-4B chain
Search

TUBB4B

0.50	Tubulin beta chain

0.71	GO:0007017	microtubule-based process
0.70	GO:0007010	cytoskeleton organization
0.47	GO:0031115	negative regulation of microtubule polymerization
0.39	GO:0060271	cilium assembly
0.36	GO:0000086	G2/M transition of mitotic cell cycle
0.36	GO:0010389	regulation of G2/M transition of mitotic cell cycle
0.36	GO:0140056	organelle localization by membrane tethering
0.35	GO:0006955	immune response
0.35	GO:0001909	leukocyte mediated cytotoxicity
0.35	GO:0002446	neutrophil mediated immunity

0.76	GO:0005200	structural constituent of cytoskeleton
0.67	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0032561	guanyl ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0003725	double-stranded RNA binding
0.41	GO:0005509	calcium ion binding
0.36	GO:0005515	protein binding

0.73	GO:0005874	microtubule
0.53	GO:0043209	myelin sheath
0.48	GO:0033269	internode region of axon
0.46	GO:0005737	cytoplasm
0.45	GO:0043025	neuronal cell body
0.44	GO:0044441	ciliary part
0.38	GO:0070062	extracellular exosome
0.36	GO:0031012	extracellular matrix
0.35	GO:0005634	nucleus
0.35	GO:0045298	tubulin complex

sp|P68400|CSK21_HUMAN
Casein kinase II subunit alpha
Search

CSNK2A1

0.78	Casein kinase II subunit alpha

0.63	GO:0006468	protein phosphorylation
0.44	GO:0030307	positive regulation of cell growth
0.43	GO:0045732	positive regulation of protein catabolic process
0.43	GO:0008284	positive regulation of cell proliferation
0.43	GO:0051336	regulation of hydrolase activity
0.42	GO:0032268	regulation of cellular protein metabolic process
0.42	GO:0030177	positive regulation of Wnt signaling pathway
0.42	GO:0035303	regulation of dephosphorylation
0.41	GO:1905818	regulation of chromosome separation
0.40	GO:0043066	negative regulation of apoptotic process

0.68	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0008013	beta-catenin binding
0.42	GO:0019888	protein phosphatase regulator activity
0.41	GO:0047485	protein N-terminus binding
0.38	GO:0042802	identical protein binding
0.36	GO:0043021	ribonucleoprotein complex binding
0.35	GO:0051879	Hsp90 protein binding

0.42	GO:0031519	PcG protein complex
0.41	GO:0016580	Sin3 complex
0.41	GO:0090545	CHD-type complex
0.40	GO:0090568	nuclear transcriptional repressor complex
0.40	GO:0005956	protein kinase CK2 complex
0.34	GO:0005886	plasma membrane
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0004674

sp|P68402|PA1B2_HUMAN
Platelet-activating factor acetylhydrolase IB subunit beta
Search

PAFAH1B2

0.85	Platelet-activating factor acetylhydrolase IB subunit beta

0.57	GO:0007283	spermatogenesis
0.54	GO:0016239	positive regulation of macroautophagy
0.50	GO:0007420	brain development
0.41	GO:0016042	lipid catabolic process
0.36	GO:0043312	neutrophil degranulation
0.35	GO:0044342	type B pancreatic cell proliferation
0.34	GO:0003323	type B pancreatic cell development
0.34	GO:0033227	dsRNA transport
0.34	GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus
0.34	GO:0009749	response to glucose

0.57	GO:0047179	platelet-activating factor acetyltransferase activity
0.47	GO:0016787	hydrolase activity
0.46	GO:0042802	identical protein binding
0.41	GO:0046982	protein heterodimerization activity
0.35	GO:0035612	AP-2 adaptor complex binding
0.35	GO:0035650	AP-1 adaptor complex binding
0.34	GO:0051032	nucleic acid transmembrane transporter activity
0.34	GO:0003725	double-stranded RNA binding

0.54	GO:0001650	fibrillar center
0.49	GO:0005829	cytosol
0.42	GO:0005886	plasma membrane
0.38	GO:0070062	extracellular exosome
0.36	GO:1904813	ficolin-1-rich granule lumen
0.36	GO:0034774	secretory granule lumen
0.34	GO:0005765	lysosomal membrane
0.30	GO:0031224	intrinsic component of membrane

0.57

EC:2.3.1.149

GO:0047179

sp|P68431|H31_HUMAN
Histone H3.1
Search

0.49	GO:0006334	nucleosome assembly
0.41	GO:0051290	protein heterotetramerization
0.40	GO:0034723	DNA replication-dependent nucleosome organization
0.39	GO:0006352	DNA-templated transcription, initiation
0.39	GO:0060968	regulation of gene silencing
0.37	GO:0000183	chromatin silencing at rDNA
0.36	GO:0038111	interleukin-7-mediated signaling pathway
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation
0.35	GO:0045652	regulation of megakaryocyte differentiation
0.35	GO:0032460	negative regulation of protein oligomerization

0.74	GO:0046982	protein heterodimerization activity
0.55	GO:0003677	DNA binding
0.45	GO:0031491	nucleosome binding
0.38	GO:0045296	cadherin binding

0.75	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.37	GO:0031974	membrane-enclosed lumen
0.35	GO:0043234	protein complex
0.34	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

sp|P68543|UBX2A_HUMAN
UBX domain-containing protein 2A
Search

UBXN2A

0.96	UBX domain containing 4

0.80	GO:1990830	cellular response to leukemia inhibitory factor
0.76	GO:0031396	regulation of protein ubiquitination
0.74	GO:0042176	regulation of protein catabolic process
0.68	GO:0031468	nuclear envelope reassembly
0.64	GO:0000045	autophagosome assembly
0.64	GO:0007030	Golgi organization
0.62	GO:0043666	regulation of phosphoprotein phosphatase activity
0.61	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.55	GO:0061025	membrane fusion
0.39	GO:0010468	regulation of gene expression

0.84	GO:0033130	acetylcholine receptor binding
0.63	GO:0043130	ubiquitin binding
0.62	GO:0019888	protein phosphatase regulator activity
0.35	GO:0003735	structural constituent of ribosome

0.78	GO:0005801	cis-Golgi network
0.67	GO:0005829	cytosol
0.67	GO:0005783	endoplasmic reticulum
0.51	GO:0005634	nucleus
0.36	GO:0045111	intermediate filament cytoskeleton
0.35	GO:0005840	ribosome
0.34	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P68871|HBB_HUMAN
Hemoglobin subunit beta
Search

HBB

0.83	Hemoglobin subunit delta

0.79	GO:0015671	oxygen transport
0.45	GO:0070293	renal absorption
0.44	GO:0051291	protein heterooligomerization
0.43	GO:0042542	response to hydrogen peroxide
0.42	GO:0010942	positive regulation of cell death
0.42	GO:0042744	hydrogen peroxide catabolic process
0.40	GO:0098869	cellular oxidant detoxification
0.36	GO:0007596	blood coagulation
0.35	GO:0030185	nitric oxide transport
0.35	GO:0043312	neutrophil degranulation

0.80	GO:0005344	oxygen carrier activity
0.79	GO:0019825	oxygen binding
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.47	GO:0031720	haptoglobin binding
0.45	GO:0030492	hemoglobin binding
0.40	GO:0004601	peroxidase activity

0.83	GO:0005833	hemoglobin complex
0.46	GO:0031838	haptoglobin-hemoglobin complex
0.41	GO:0005615	extracellular space
0.36	GO:0071682	endocytic vesicle lumen
0.35	GO:1904724	tertiary granule lumen
0.35	GO:1904813	ficolin-1-rich granule lumen
0.34	GO:1903561	extracellular vesicle
0.30	GO:0031224	intrinsic component of membrane

0.40	EC:1.11.1.7	GO:0004601
0.40	KEGG:R03532	GO:0004601

sp|P69849|NOMO3_HUMAN
Nodal modulator 3
Search

NOMO1

0.90	Nodal modulator 3

0.45	GO:1900176	negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry
0.37	GO:0031648	protein destabilization

0.69	GO:0030246	carbohydrate binding
0.33	GO:0005515	protein binding

0.41	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P69891|HBG1_HUMAN
Hemoglobin subunit gamma-1
Search

0.82	G-gamma globin Paulinia variant

0.79	GO:0015671	oxygen transport
0.40	GO:0000122	negative regulation of transcription by RNA polymerase II
0.40	GO:0051291	protein heterooligomerization
0.37	GO:0007596	blood coagulation
0.37	GO:0014070	response to organic cyclic compound
0.36	GO:0070293	renal absorption
0.36	GO:0042542	response to hydrogen peroxide
0.35	GO:0010942	positive regulation of cell death
0.35	GO:0042744	hydrogen peroxide catabolic process
0.34	GO:0098869	cellular oxidant detoxification

0.80	GO:0005344	oxygen carrier activity
0.79	GO:0019825	oxygen binding
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.40	GO:0030492	hemoglobin binding
0.37	GO:0031720	haptoglobin binding
0.34	GO:0004601	peroxidase activity

0.83	GO:0005833	hemoglobin complex
0.37	GO:0072562	blood microparticle
0.37	GO:0031838	haptoglobin-hemoglobin complex

0.34	EC:1.11.1.7	GO:0004601
0.34	KEGG:R03532	GO:0004601

sp|P69892|HBG2_HUMAN
Hemoglobin subunit gamma-2
Search

0.82	G-gamma globin Paulinia variant

0.79	GO:0015671	oxygen transport
0.40	GO:0000122	negative regulation of transcription by RNA polymerase II
0.40	GO:0051291	protein heterooligomerization
0.37	GO:0007596	blood coagulation
0.37	GO:0014070	response to organic cyclic compound
0.36	GO:0070293	renal absorption
0.36	GO:0042542	response to hydrogen peroxide
0.35	GO:0010942	positive regulation of cell death
0.35	GO:0042744	hydrogen peroxide catabolic process
0.34	GO:0098869	cellular oxidant detoxification

0.80	GO:0005344	oxygen carrier activity
0.79	GO:0019825	oxygen binding
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.40	GO:0030492	hemoglobin binding
0.37	GO:0031720	haptoglobin binding
0.34	GO:0004601	peroxidase activity

0.83	GO:0005833	hemoglobin complex
0.37	GO:0072562	blood microparticle
0.37	GO:0031838	haptoglobin-hemoglobin complex

0.34	EC:1.11.1.7	GO:0004601
0.34	KEGG:R03532	GO:0004601

sp|P69905|HBA_HUMAN
Hemoglobin subunit alpha
Search

HBA

0.77	Hemoglobin subunit alpha-B

0.79	GO:0015671	oxygen transport
0.36	GO:0051291	protein heterooligomerization
0.36	GO:0042542	response to hydrogen peroxide
0.36	GO:0010942	positive regulation of cell death
0.35	GO:0042744	hydrogen peroxide catabolic process
0.35	GO:0015701	bicarbonate transport
0.35	GO:0098869	cellular oxidant detoxification
0.34	GO:0006898	receptor-mediated endocytosis

0.80	GO:0005344	oxygen carrier activity
0.79	GO:0019825	oxygen binding
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.38	GO:0031720	haptoglobin binding
0.35	GO:0004601	peroxidase activity

0.83	GO:0005833	hemoglobin complex
0.37	GO:0031838	haptoglobin-hemoglobin complex
0.36	GO:0022627	cytosolic small ribosomal subunit
0.35	GO:0071682	endocytic vesicle lumen
0.35	GO:0005615	extracellular space
0.34	GO:1903561	extracellular vesicle
0.30	GO:0016020	membrane

0.35	EC:1.11.1.7	GO:0004601
0.35	KEGG:R03532	GO:0004601

sp|P78310|CXAR_HUMAN
Coxsackievirus and adenovirus receptor
Search

CXADR

0.95	Coxsackie virus and adenovirus receptor

0.50	GO:0048739	cardiac muscle fiber development
0.49	GO:0086067	AV node cell to bundle of His cell communication
0.48	GO:0008354	germ cell migration
0.48	GO:0010669	epithelial structure maintenance
0.48	GO:0030593	neutrophil chemotaxis
0.48	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.48	GO:0034109	homotypic cell-cell adhesion
0.47	GO:0045216	cell-cell junction organization
0.45	GO:0031532	actin cytoskeleton reorganization
0.44	GO:0046629	gamma-delta T cell activation

0.49	GO:0071253	connexin binding
0.48	GO:0008013	beta-catenin binding
0.48	GO:0030165	PDZ domain binding
0.46	GO:0050839	cell adhesion molecule binding
0.44	GO:0001618	virus receptor activity
0.39	GO:0086082	cell adhesive protein binding involved in AV node cell-bundle of His cell communication
0.39	GO:0032403	protein complex binding
0.39	GO:0005102	receptor binding
0.37	GO:0042802	identical protein binding

0.51	GO:0005923	bicellular tight junction
0.49	GO:0016327	apicolateral plasma membrane
0.47	GO:0030175	filopodium
0.47	GO:0030426	growth cone
0.47	GO:0001669	acrosomal vesicle
0.47	GO:0016323	basolateral plasma membrane
0.46	GO:0014704	intercalated disc
0.46	GO:0005912	adherens junction
0.46	GO:0045121	membrane raft
0.46	GO:0044297	cell body

sp|P78312|F193A_HUMAN
Protein FAM193A
Search

sp|P78314|3BP2_HUMAN
SH3 domain-binding protein 2
Search

SH3BP2

0.97	SH3 domain-binding protein 2

0.75	GO:0009967	positive regulation of signal transduction
0.60	GO:0007165	signal transduction

0.85	GO:0005070	SH3/SH2 adaptor activity
0.58	GO:0001784	phosphotyrosine residue binding
0.40	GO:0017124	SH3 domain binding

sp|P78316|NOP14_HUMAN
Nucleolar protein 14
Search

NOP14

0.91	Nucleolar complex protein 14

0.47	GO:0030490	maturation of SSU-rRNA
0.36	GO:0060218	hematopoietic stem cell differentiation
0.36	GO:0000479	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.35	GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
0.35	GO:0000967	rRNA 5'-end processing
0.34	GO:0055085	transmembrane transport
0.33	GO:0007018	microtubule-based movement
0.31	GO:0007165	signal transduction

0.51	GO:0019899	enzyme binding
0.37	GO:0030515	snoRNA binding
0.34	GO:0005215	transporter activity
0.33	GO:0003777	microtubule motor activity
0.33	GO:0008017	microtubule binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.79	GO:0032040	small-subunit processome
0.53	GO:0005730	nucleolus
0.51	GO:0030692	Noc4p-Nop14p complex
0.34	GO:0005654	nucleoplasm
0.32	GO:0005856	cytoskeleton
0.30	GO:0016020	membrane

sp|P78317|RNF4_HUMAN
E3 ubiquitin-protein ligase RNF4
Search

RNF4

0.90	Ring finger protein 4

0.85	GO:0090234	regulation of kinetochore assembly
0.81	GO:0090169	regulation of spindle assembly
0.76	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.76	GO:0046685	response to arsenic-containing substance
0.70	GO:0045944	positive regulation of transcription by RNA polymerase II
0.56	GO:0016567	protein ubiquitination

0.69	GO:0042802	identical protein binding
0.67	GO:0008134	transcription factor binding
0.58	GO:0061630	ubiquitin protein ligase activity
0.36	GO:0046872	metal ion binding

0.84	GO:0016605	PML body
0.47	GO:0005737	cytoplasm

sp|P78318|IGBP1_HUMAN
Immunoglobulin-binding protein 1
Search

IGBP1

0.95	Immunoglobulin-binding protein 1

0.70	GO:0009966	regulation of signal transduction
0.55	GO:0035304	regulation of protein dephosphorylation
0.52	GO:0010921	regulation of phosphatase activity
0.49	GO:0035306	positive regulation of dephosphorylation
0.48	GO:0043066	negative regulation of apoptotic process
0.47	GO:0035305	negative regulation of dephosphorylation
0.46	GO:0031400	negative regulation of protein modification process
0.46	GO:0023057	negative regulation of signaling
0.46	GO:0010648	negative regulation of cell communication
0.45	GO:0048585	negative regulation of response to stimulus

0.54	GO:0051721	protein phosphatase 2A binding
0.52	GO:0019888	protein phosphatase regulator activity
0.50	GO:0031434	mitogen-activated protein kinase kinase binding
0.46	GO:0019904	protein domain specific binding
0.37	GO:0032403	protein complex binding
0.33	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
0.33	GO:0070008	serine-type exopeptidase activity
0.32	GO:0004252	serine-type endopeptidase activity

0.46	GO:0005829	cytosol
0.45	GO:0005874	microtubule
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0016747

sp|P78324|SHPS1_HUMAN
Tyrosine-protein phosphatase non-receptor type substrate 1
Search

SIRPA

0.94	Tyrosine-protein phosphatase non-receptor type substrate 1

0.39	GO:0008284	positive regulation of cell proliferation
0.38	GO:0050870	positive regulation of T cell activation
0.38	GO:0002376	immune system process
0.37	GO:0007155	cell adhesion
0.37	GO:0016477	cell migration
0.37	GO:0045055	regulated exocytosis
0.37	GO:0006910	phagocytosis, recognition
0.37	GO:0050766	positive regulation of phagocytosis
0.37	GO:0006911	phagocytosis, engulfment
0.37	GO:0001775	cell activation

0.39	GO:0017124	SH3 domain binding
0.35	GO:0045309	protein phosphorylated amino acid binding

0.38	GO:0070062	extracellular exosome
0.37	GO:0030667	secretory granule membrane
0.36	GO:0101002	ficolin-1-rich granule
0.36	GO:0070820	tertiary granule
0.35	GO:0005887	integral component of plasma membrane

sp|P78325|ADAM8_HUMAN
Disintegrin and metalloproteinase domain-containing protein 8
Search

ADAM8

0.92	Disintegrin and metalloproteinase domain-containing protein 8

0.61	GO:0006508	proteolysis
0.59	GO:0007229	integrin-mediated signaling pathway
0.58	GO:2000391	positive regulation of neutrophil extravasation
0.57	GO:0051044	positive regulation of membrane protein ectodomain proteolysis
0.56	GO:2000415	positive regulation of fibronectin-dependent thymocyte migration
0.55	GO:2000309	positive regulation of tumor necrosis factor (ligand) superfamily member 11 production
0.55	GO:2000418	positive regulation of eosinophil migration
0.55	GO:0071456	cellular response to hypoxia
0.54	GO:0070245	positive regulation of thymocyte apoptotic process
0.54	GO:0033089	positive regulation of T cell differentiation in thymus

0.70	GO:0004222	metalloendopeptidase activity
0.53	GO:0046872	metal ion binding
0.53	GO:0050839	cell adhesion molecule binding
0.49	GO:0090729	toxin activity
0.39	GO:0002020	protease binding
0.37	GO:0043621	protein self-association
0.35	GO:0004252	serine-type endopeptidase activity
0.35	GO:0016504	peptidase activator activity
0.35	GO:0032403	protein complex binding
0.34	GO:0005102	receptor binding

0.60	GO:0032127	dense core granule membrane
0.59	GO:0071065	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex
0.58	GO:0032010	phagolysosome
0.57	GO:0070820	tertiary granule
0.56	GO:0042581	specific granule
0.56	GO:0002102	podosome
0.55	GO:0071133	alpha9-beta1 integrin-ADAM8 complex
0.50	GO:0009986	cell surface
0.47	GO:0005887	integral component of plasma membrane
0.38	GO:0101002	ficolin-1-rich granule

0.70

GO:0004222

sp|P78329|CP4F2_HUMAN
Phylloquinone omega-hydroxylase CYP4F2
Search

0.96	Cytochrome P450 family 4 subfamily F member 2

0.58	GO:0036102	leukotriene B4 metabolic process
0.58	GO:0036100	leukotriene catabolic process
0.55	GO:0042758	long-chain fatty acid catabolic process
0.55	GO:0003095	pressure natriuresis
0.54	GO:0006775	fat-soluble vitamin metabolic process
0.53	GO:0055114	oxidation-reduction process
0.52	GO:0003091	renal water homeostasis
0.52	GO:0019373	epoxygenase P450 pathway
0.51	GO:0055078	sodium ion homeostasis
0.50	GO:0000038	very long-chain fatty acid metabolic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.67	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.46	GO:0005504	fatty acid binding
0.41	GO:0019825	oxygen binding

0.49	GO:0016324	apical plasma membrane
0.40	GO:0043231	intracellular membrane-bounded organelle
0.39	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.39	GO:0031984	organelle subcompartment
0.38	GO:0005737	cytoplasm
0.37	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

0.68

GO:0016705

sp|P78330|SERB_HUMAN
Phosphoserine phosphatase
Search

PSPH

0.49	Phosphoserine phosphatase

0.76	GO:0006564	L-serine biosynthetic process
0.68	GO:0016311	dephosphorylation
0.40	GO:0033574	response to testosterone
0.39	GO:0009612	response to mechanical stimulus
0.38	GO:0031667	response to nutrient levels
0.32	GO:0008283	cell proliferation

0.81	GO:0004647	phosphoserine phosphatase activity
0.48	GO:0042803	protein homodimerization activity
0.46	GO:0005509	calcium ion binding
0.44	GO:0000287	magnesium ion binding

0.38	GO:0043005	neuron projection
0.34	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

0.81

EC:3.1.3.3

GO:0004647

sp|P78332|RBM6_HUMAN
RNA-binding protein 6
Search

RBM6

0.90	RNA binding motif protein 6

0.39	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.38	GO:0006396	RNA processing
0.37	GO:0042981	regulation of apoptotic process
0.35	GO:0043068	positive regulation of programmed cell death
0.35	GO:0022618	ribonucleoprotein complex assembly
0.34	GO:0016071	mRNA metabolic process

0.59	GO:0003723	RNA binding
0.36	GO:0005515	protein binding
0.34	GO:0003677	DNA binding
0.34	GO:0046872	metal ion binding

0.50	GO:0005634	nucleus
0.35	GO:0030529	intracellular ribonucleoprotein complex
0.35	GO:0044446	intracellular organelle part
0.34	GO:0031974	membrane-enclosed lumen

sp|P78333|GPC5_HUMAN
Glypican-5
Search

GPC5

0.95	Glypican-5 isoform A

0.70	GO:0009966	regulation of signal transduction
0.39	GO:0061209	cell proliferation involved in mesonephros development
0.39	GO:0072180	mesonephric duct morphogenesis
0.39	GO:0072203	cell proliferation involved in metanephros development
0.39	GO:0010463	mesenchymal cell proliferation
0.39	GO:0035116	embryonic hindlimb morphogenesis
0.38	GO:0030282	bone mineralization
0.38	GO:0030316	osteoclast differentiation
0.38	GO:0046326	positive regulation of glucose import
0.38	GO:0060976	coronary vasculature development

0.85	GO:0043395	heparan sulfate proteoglycan binding
0.40	GO:0060422	peptidyl-dipeptidase inhibitor activity

0.82	GO:0046658	anchored component of plasma membrane
0.76	GO:0005578	proteinaceous extracellular matrix
0.39	GO:0005796	Golgi lumen
0.39	GO:0005764	lysosome
0.37	GO:0005615	extracellular space
0.37	GO:0005775	vacuolar lumen
0.36	GO:0005887	integral component of plasma membrane

sp|P78334|GBRE_HUMAN
Gamma-aminobutyric acid receptor subunit epsilon
Search

GABRE

0.92	Gamma-aminobutyric acid type A receptor epsilon subunit

0.69	GO:0007214	gamma-aminobutyric acid signaling pathway
0.68	GO:0006821	chloride transport
0.61	GO:2001226	negative regulation of chloride transport
0.60	GO:0034220	ion transmembrane transport
0.47	GO:0007268	chemical synaptic transmission
0.36	GO:0071420	cellular response to histamine
0.35	GO:0030534	adult behavior
0.35	GO:0009791	post-embryonic development
0.34	GO:0042493	response to drug

0.82	GO:0004890	GABA-A receptor activity
0.75	GO:0005230	extracellular ligand-gated ion channel activity
0.57	GO:0099095	ligand-gated anion channel activity
0.54	GO:0005254	chloride channel activity
0.52	GO:0022835	transmitter-gated channel activity
0.37	GO:0050811	GABA receptor binding

0.58	GO:1902711	GABA-A receptor complex
0.55	GO:0005886	plasma membrane
0.41	GO:0034707	chloride channel complex
0.40	GO:0098794	postsynapse
0.40	GO:0030054	cell junction
0.35	GO:0030424	axon
0.34	GO:0060077	inhibitory synapse
0.34	GO:0030425	dendrite
0.34	GO:0031252	cell leading edge
0.34	GO:0030659	cytoplasmic vesicle membrane

sp|P78337|PITX1_HUMAN
Pituitary homeobox 1
Search

PITX1

0.91	Pituitary homeobox 1

0.68	GO:0007275	multicellular organism development
0.58	GO:0048625	myoblast fate commitment
0.56	GO:0014706	striated muscle tissue development
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0060322	head development
0.55	GO:0010468	regulation of gene expression
0.54	GO:0006366	transcription by RNA polymerase II
0.53	GO:0061448	connective tissue development
0.53	GO:0051254	positive regulation of RNA metabolic process

0.62	GO:0043565	sequence-specific DNA binding
0.60	GO:0003700	DNA binding transcription factor activity
0.59	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.58	GO:0001085	RNA polymerase II transcription factor binding
0.54	GO:0044212	transcription regulatory region DNA binding
0.52	GO:0003690	double-stranded DNA binding
0.46	GO:0033613	activating transcription factor binding
0.44	GO:0003713	transcription coactivator activity
0.44	GO:0031490	chromatin DNA binding
0.44	GO:0001104	RNA polymerase II transcription cofactor activity

0.60	GO:0005634	nucleus
0.54	GO:0005667	transcription factor complex
0.46	GO:0070013	intracellular organelle lumen
0.43	GO:0043232	intracellular non-membrane-bounded organelle
0.42	GO:0044446	intracellular organelle part
0.40	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

sp|P78344|IF4G2_HUMAN
Eukaryotic translation initiation factor 4 gamma 2
Search

EIF4G2

0.93	Eukaryotic translation initiation factor 4 gamma 2

0.62	GO:0006413	translational initiation
0.43	GO:0007498	mesoderm development
0.40	GO:0030307	positive regulation of cell growth
0.40	GO:0006446	regulation of translational initiation
0.39	GO:0060999	positive regulation of dendritic spine development
0.38	GO:0050772	positive regulation of axonogenesis
0.38	GO:0030516	regulation of axon extension
0.38	GO:0048639	positive regulation of developmental growth
0.37	GO:0007507	heart development
0.37	GO:0045727	positive regulation of translation

0.63	GO:0003743	translation initiation factor activity
0.38	GO:0045296	cadherin binding

0.47	GO:0005829	cytosol
0.43	GO:0016281	eukaryotic translation initiation factor 4F complex
0.38	GO:0005913	cell-cell adherens junction
0.38	GO:0030424	axon
0.30	GO:0016020	membrane

sp|P78345|RPP38_HUMAN
Ribonuclease P protein subunit p38
Search

RPP38

0.97	Ribonuclease P protein subunit p38

0.44	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic
0.42	GO:0008033	tRNA processing
0.38	GO:0006364	rRNA processing

0.46	GO:0004526	ribonuclease P activity
0.37	GO:0005515	protein binding

0.81	GO:0001650	fibrillar center
0.65	GO:0005655	nucleolar ribonuclease P complex
0.38	GO:0005654	nucleoplasm

0.46

EC:3.1.26.5

GO:0004526

sp|P78346|RPP30_HUMAN
Ribonuclease P protein subunit p30
Search

RPP30

0.94	Ribonuclease P protein subunit p30

0.66	GO:0090501	RNA phosphodiester bond hydrolysis
0.63	GO:0008033	tRNA processing
0.39	GO:0043043	peptide biosynthetic process
0.38	GO:0044267	cellular protein metabolic process
0.37	GO:0009059	macromolecule biosynthetic process
0.34	GO:0006364	rRNA processing

0.67	GO:0004540	ribonuclease activity
0.52	GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
0.49	GO:0140101	catalytic activity, acting on a tRNA
0.40	GO:0003735	structural constituent of ribosome
0.40	GO:0003723	RNA binding
0.34	GO:0005515	protein binding

0.58	GO:0030681	multimeric ribonuclease P complex
0.56	GO:0000172	ribonuclease MRP complex
0.46	GO:0044452	nucleolar part
0.40	GO:0005840	ribosome
0.34	GO:0005654	nucleoplasm

0.52

EC:3.1.30

GO:0016893

sp|P78347|GTF2I_HUMAN
General transcription factor II-I
Search

GTF2I

0.57	general transcription factor II-I

0.59	GO:0014886	transition between slow and fast fiber
0.59	GO:0006366	transcription by RNA polymerase II
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0016525	negative regulation of angiogenesis
0.43	GO:0007275	multicellular organism development
0.30	GO:0072507	divalent inorganic cation homeostasis
0.30	GO:0007165	signal transduction
0.30	GO:0006352	DNA-templated transcription, initiation

0.57	GO:0051019	mitogen-activated protein kinase binding
0.55	GO:0003677	DNA binding
0.52	GO:0003700	DNA binding transcription factor activity

0.61	GO:0005634	nucleus
0.53	GO:0043025	neuronal cell body
0.47	GO:0042995	cell projection
0.47	GO:0031974	membrane-enclosed lumen
0.43	GO:0044446	intracellular organelle part
0.36	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P78348|ASIC1_HUMAN
Acid-sensing ion channel 1
Search

ASIC1

0.87	Amiloride-sensitive sodium channel subunit beta

0.77	GO:0035725	sodium ion transmembrane transport
0.57	GO:0050915	sensory perception of sour taste
0.55	GO:0046929	negative regulation of neurotransmitter secretion
0.54	GO:0071467	cellular response to pH
0.53	GO:0010447	response to acidic pH
0.53	GO:0008306	associative learning
0.52	GO:0007613	memory
0.50	GO:0042391	regulation of membrane potential
0.49	GO:0070588	calcium ion transmembrane transport
0.41	GO:0070207	protein homotrimerization

0.84	GO:0015280	ligand-gated sodium channel activity
0.36	GO:0005515	protein binding
0.34	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity
0.33	GO:0051287	NAD binding

0.49	GO:0045202	synapse
0.47	GO:0005794	Golgi apparatus
0.47	GO:0005887	integral component of plasma membrane
0.37	GO:0009986	cell surface
0.36	GO:0097458	neuron part
0.34	GO:0120038	plasma membrane bounded cell projection part
0.34	GO:0016514	SWI/SNF complex
0.34	GO:0009331	glycerol-3-phosphate dehydrogenase complex

0.34	EC:1.1.1.8 EC:1.1.1.94	GO:0004367
0.34	KEGG:R00842	GO:0004367

sp|P78352|DLG4_HUMAN
Disks large homolog 4
Search

DLG4

0.89	Disks large like protein 4

0.79	GO:2000821	regulation of grooming behavior
0.77	GO:0035641	locomotory exploration behavior
0.76	GO:0071625	vocalization behavior
0.76	GO:0060997	dendritic spine morphogenesis
0.76	GO:0016188	synaptic vesicle maturation
0.76	GO:0048169	regulation of long-term neuronal synaptic plasticity
0.76	GO:0035418	protein localization to synapse
0.75	GO:0097120	receptor localization to synapse
0.74	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity
0.74	GO:0035176	social behavior

0.84	GO:0035255	ionotropic glutamate receptor binding
0.75	GO:0031811	G-protein coupled nucleotide receptor binding
0.74	GO:0097110	scaffold protein binding
0.71	GO:0008022	protein C-terminus binding
0.71	GO:0031697	beta-1 adrenergic receptor binding
0.71	GO:0097109	neuroligin family protein binding
0.70	GO:0031748	D1 dopamine receptor binding
0.68	GO:0004385	guanylate kinase activity
0.67	GO:0033130	acetylcholine receptor binding
0.67	GO:0019900	kinase binding

0.81	GO:0008328	ionotropic glutamate receptor complex
0.78	GO:0014069	postsynaptic density
0.78	GO:0044300	cerebellar mossy fiber
0.77	GO:0044224	juxtaparanode region of axon
0.77	GO:0099634	postsynaptic specialization membrane
0.75	GO:0060076	excitatory synapse
0.73	GO:0043197	dendritic spine
0.72	GO:0044306	neuron projection terminus
0.71	GO:0016323	basolateral plasma membrane
0.70	GO:0008021	synaptic vesicle

0.68

EC:2.7.4.8

GO:0004385

sp|P78356|PI42B_HUMAN
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta
Search

PIP4K2B

0.93	Phosphatidylinositol-4-phosphate 5-kinase type II beta

0.75	GO:0046854	phosphatidylinositol phosphorylation
0.61	GO:2000786	positive regulation of autophagosome assembly
0.47	GO:0035855	megakaryocyte development
0.36	GO:0014066	regulation of phosphatidylinositol 3-kinase signaling
0.35	GO:0006661	phosphatidylinositol biosynthetic process
0.34	GO:0048634	regulation of muscle organ development
0.34	GO:0007166	cell surface receptor signaling pathway

0.82	GO:0016307	phosphatidylinositol phosphate kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0042803	protein homodimerization activity
0.34	GO:0005057	signal transducer activity, downstream of receptor

0.58	GO:0005776	autophagosome
0.47	GO:0005654	nucleoplasm
0.36	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0005829	cytosol
0.34	GO:0005886	plasma membrane

0.82

GO:0016307

sp|P78357|CNTP1_HUMAN
Contactin-associated protein 1
Search

CNTNAP1

0.81	Contactin associated protein like 5

0.85	GO:0030913	paranodal junction assembly
0.70	GO:0002175	protein localization to paranode region of axon
0.69	GO:0098870	action potential propagation
0.68	GO:0022010	central nervous system myelination
0.68	GO:0071205	protein localization to juxtaparanode region of axon
0.67	GO:0050884	neuromuscular process controlling posture
0.66	GO:0022011	myelination in peripheral nervous system
0.66	GO:0050885	neuromuscular process controlling balance
0.65	GO:0019226	transmission of nerve impulse
0.61	GO:0048812	neuron projection morphogenesis

0.41	GO:0017124	SH3 domain binding
0.38	GO:0005070	SH3/SH2 adaptor activity
0.35	GO:0004872	receptor activity

0.84	GO:0033270	paranode region of axon
0.63	GO:0043209	myelin sheath
0.60	GO:0008076	voltage-gated potassium channel complex
0.44	GO:0033010	paranodal junction

sp|P78358|CTG1B_HUMAN
Cancer/testis antigen 1
Search

CTAG2

0.96	Cancer/testis antigen 1

0.63

GO:0005515

protein binding

0.60	GO:0005813	centrosome
0.45	GO:0005737	cytoplasm

sp|P78362|SRPK2_HUMAN
SRSF protein kinase 2
Search

SRPK2

0.95	SRSF protein kinase 2

0.63	GO:0006468	protein phosphorylation
0.59	GO:0045070	positive regulation of viral genome replication
0.58	GO:0045071	negative regulation of viral genome replication
0.57	GO:0000245	spliceosomal complex assembly
0.54	GO:0008284	positive regulation of cell proliferation
0.47	GO:0035556	intracellular signal transduction
0.45	GO:0050684	regulation of mRNA processing
0.42	GO:0035063	nuclear speck organization
0.41	GO:0043525	positive regulation of neuron apoptotic process
0.40	GO:0001525	angiogenesis

0.63	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0000287	magnesium ion binding
0.41	GO:0071889	14-3-3 protein binding
0.35	GO:0003723	RNA binding

0.51	GO:0005730	nucleolus
0.49	GO:0005654	nucleoplasm
0.49	GO:0005829	cytosol

sp|P78363|ABCA4_HUMAN
Retinal-specific ATP-binding cassette transporter
Search

ABCA4

0.74	Retinal-specific ATP-binding cassette transporter

0.76	GO:0006649	phospholipid transfer to membrane
0.70	GO:0045494	photoreceptor cell maintenance
0.69	GO:0007601	visual perception
0.65	GO:0045332	phospholipid translocation
0.55	GO:0055085	transmembrane transport
0.39	GO:0007603	phototransduction, visible light
0.38	GO:0001523	retinoid metabolic process
0.33	GO:0015698	inorganic anion transport

0.76	GO:0090555	phosphatidylethanolamine-translocating ATPase activity
0.66	GO:0042626	ATPase activity, coupled to transmembrane movement of substances
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0005452	inorganic anion exchanger activity

0.69	GO:0001750	photoreceptor outer segment
0.58	GO:0005887	integral component of plasma membrane
0.41	GO:0043231	intracellular membrane-bounded organelle
0.38	GO:0060170	ciliary membrane

sp|P78364|PHC1_HUMAN
Polyhomeotic-like protein 1
Search

PHC1

0.92	Polyhomeotic homolog 1 (Drosophila)

0.70	GO:0016574	histone ubiquitination
0.39	GO:0071300	cellular response to retinoic acid
0.39	GO:1990830	cellular response to leukemia inhibitory factor
0.34	GO:0007283	spermatogenesis

0.63	GO:0008270	zinc ion binding
0.37	GO:0003682	chromatin binding
0.34	GO:0042802	identical protein binding

0.72	GO:0035102	PRC1 complex
0.40	GO:0001739	sex chromatin
0.38	GO:0016604	nuclear body

sp|P78367|NKX32_HUMAN
Homeobox protein Nkx-3.2
Search

NKX3-2

0.96	Homeobox protein Nkx-3.2

0.61	GO:0060576	intestinal epithelial cell development
0.60	GO:0042474	middle ear morphogenesis
0.60	GO:0032331	negative regulation of chondrocyte differentiation
0.60	GO:0048706	embryonic skeletal system development
0.60	GO:0048536	spleen development
0.59	GO:0048705	skeletal system morphogenesis
0.59	GO:0048645	animal organ formation
0.58	GO:0031016	pancreas development
0.57	GO:0007368	determination of left/right symmetry
0.56	GO:2001141	regulation of RNA biosynthetic process

0.64	GO:0043565	sequence-specific DNA binding
0.58	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.54	GO:0001012	RNA polymerase II regulatory region DNA binding
0.52	GO:0003690	double-stranded DNA binding
0.36	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.34	GO:0097162	MADS box domain binding
0.34	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process
0.34	GO:0004882	androgen receptor activity
0.33	GO:0030284	estrogen receptor activity
0.33	GO:0030331	estrogen receptor binding

0.61	GO:0005634	nucleus
0.35	GO:0070013	intracellular organelle lumen
0.34	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.33

EC:3.5.4.4

GO:0004000

sp|P78368|KC1G2_HUMAN
Casein kinase I isoform gamma-2
Search

CSNK1G2

0.76	Casein kinase I

0.63	GO:0006468	protein phosphorylation
0.53	GO:0018209	peptidyl-serine modification
0.43	GO:0016055	Wnt signaling pathway
0.42	GO:0006897	endocytosis
0.41	GO:0008360	regulation of cell shape
0.35	GO:0030148	sphingolipid biosynthetic process

0.69	GO:0004674	protein serine/threonine kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0051219	phosphoprotein binding
0.36	GO:0042277	peptide binding
0.34	GO:0000287	magnesium ion binding

0.39	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.69

GO:0004674

sp|P78369|CLD10_HUMAN
Claudin-10
Search

CLDN10

0.67

Claudin

0.54	GO:0043269	regulation of ion transport
0.38	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
0.36	GO:0006811	ion transport
0.35	GO:0098870	action potential propagation
0.34	GO:0019226	transmission of nerve impulse
0.34	GO:0043297	apical junction assembly
0.34	GO:0048546	digestive tract morphogenesis
0.34	GO:0035148	tube formation
0.31	GO:0055114	oxidation-reduction process

0.62	GO:0005198	structural molecule activity
0.36	GO:0042802	identical protein binding
0.33	GO:0031418	L-ascorbic acid binding
0.32	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.32	GO:0005506	iron ion binding

0.81	GO:0005923	bicellular tight junction
0.55	GO:0005886	plasma membrane
0.40	GO:0005737	cytoplasm
0.34	GO:0012505	endomembrane system
0.33	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.32

GO:0016705

sp|P78371|TCPB_HUMAN
T-complex protein 1 subunit beta
Search

CCT2

0.84	T-complex protein 1 subunit beta

0.69	GO:0006457	protein folding
0.57	GO:0090670	RNA localization to Cajal body
0.56	GO:1904869	regulation of protein localization to Cajal body
0.56	GO:1904851	positive regulation of establishment of protein localization to telomere
0.55	GO:1904874	positive regulation of telomerase RNA localization to Cajal body
0.54	GO:0007339	binding of sperm to zona pellucida
0.54	GO:0051973	positive regulation of telomerase activity
0.54	GO:0032212	positive regulation of telomere maintenance via telomerase
0.53	GO:1900182	positive regulation of protein localization to nucleus
0.52	GO:0051131	chaperone-mediated protein complex assembly

0.71	GO:0051082	unfolded protein binding
0.56	GO:0044183	protein binding involved in protein folding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0031625	ubiquitin protein ligase binding

0.56	GO:0005832	chaperonin-containing T-complex
0.56	GO:0002199	zona pellucida receptor complex
0.53	GO:0043209	myelin sheath
0.52	GO:0044297	cell body
0.48	GO:0005874	microtubule
0.37	GO:0070062	extracellular exosome
0.36	GO:0031012	extracellular matrix
0.35	GO:0035578	azurophil granule lumen

sp|P78380|OLR1_HUMAN
Oxidized low-density lipoprotein receptor 1
Search

OLR1

0.97	Oxidized low-density lipoprotein receptor

0.46	GO:0002376	immune system process
0.46	GO:0006910	phagocytosis, recognition
0.45	GO:0006954	inflammatory response
0.44	GO:0045089	positive regulation of innate immune response
0.44	GO:0002764	immune response-regulating signaling pathway
0.41	GO:0007155	cell adhesion
0.40	GO:0008015	blood circulation
0.38	GO:0001775	cell activation
0.38	GO:0045055	regulated exocytosis
0.38	GO:0006898	receptor-mediated endocytosis

0.68	GO:0030246	carbohydrate binding
0.54	GO:0042802	identical protein binding
0.46	GO:0038187	pattern recognition receptor activity
0.40	GO:0005041	low-density lipoprotein receptor activity
0.40	GO:0038023	signaling receptor activity
0.35	GO:0042287	MHC protein binding
0.34	GO:0023024	MHC class I protein complex binding
0.34	GO:0023025	MHC class Ib protein complex binding
0.34	GO:1990405	protein antigen binding
0.33	GO:0046872	metal ion binding

0.57	GO:0043235	receptor complex
0.56	GO:0005654	nucleoplasm
0.46	GO:0005886	plasma membrane
0.43	GO:0045121	membrane raft
0.40	GO:0005576	extracellular region
0.39	GO:0035579	specific granule membrane
0.39	GO:0070821	tertiary granule membrane
0.33	GO:0009986	cell surface
0.33	GO:0019898	extrinsic component of membrane
0.30	GO:0016021	integral component of membrane

sp|P78381|S35A2_HUMAN
UDP-galactose translocator
Search

SLC35A2

0.93	Solute carrier family 35 (UDP-galactose transporter), member 2

0.69	GO:0008643	carbohydrate transport
0.63	GO:1902600	hydrogen ion transmembrane transport
0.36	GO:1990569	UDP-N-acetylglucosamine transmembrane transport

0.79

GO:0005351

sugar:proton symporter activity

0.74	GO:0000139	Golgi membrane
0.53	GO:0005783	endoplasmic reticulum
0.48	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|P78382|S35A1_HUMAN
CMP-sialic acid transporter
Search

SLC35A1

0.91	CMP-sialic acid transporter

0.69	GO:0008643	carbohydrate transport
0.63	GO:1902600	hydrogen ion transmembrane transport
0.39	GO:0015782	CMP-N-acetylneuraminate transmembrane transport
0.34	GO:0005975	carbohydrate metabolic process
0.34	GO:0036211	protein modification process
0.33	GO:0044267	cellular protein metabolic process

0.79	GO:0005351	sugar:proton symporter activity
0.39	GO:0005456	CMP-N-acetylneuraminate transmembrane transporter activity

0.74	GO:0000139	Golgi membrane
0.35	GO:0005887	integral component of plasma membrane

sp|P78383|S35B1_HUMAN
Solute carrier family 35 member B1
Search

SLC35B1

0.93	Solute carrier family 35 member B1

0.54	GO:0055085	transmembrane transport
0.44	GO:1901264	carbohydrate derivative transport
0.44	GO:0015931	nucleobase-containing compound transport
0.42	GO:0015711	organic anion transport
0.40	GO:0008643	carbohydrate transport

0.49

GO:0005459

UDP-galactose transmembrane transporter activity

0.47	GO:0030173	integral component of Golgi membrane
0.45	GO:0030176	integral component of endoplasmic reticulum membrane

sp|P78385|KRT83_HUMAN
Keratin, type II cuticular Hb3
Search

0.92	Keratin, type II microfibrillar, component 7C

0.42	GO:0042633	hair cycle
0.40	GO:0007568	aging
0.39	GO:0070268	cornification
0.36	GO:0045103	intermediate filament-based process
0.35	GO:0007010	cytoskeleton organization
0.33	GO:0006811	ion transport

0.62	GO:0005198	structural molecule activity
0.35	GO:0005515	protein binding

0.83	GO:0045095	keratin filament
0.41	GO:0005615	extracellular space
0.39	GO:1903561	extracellular vesicle
0.36	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|P78386|KRT85_HUMAN
Keratin, type II cuticular Hb5
Search

KRT85

0.86	Type II keratin Kb25

0.48	GO:0042633	hair cycle
0.46	GO:0007568	aging
0.40	GO:0045103	intermediate filament-based process
0.38	GO:0007010	cytoskeleton organization

0.62

GO:0005198

structural molecule activity

0.83	GO:0045095	keratin filament
0.48	GO:0005615	extracellular space
0.43	GO:1903561	extracellular vesicle

sp|P78395|PRAME_HUMAN
Melanoma antigen preferentially expressed in tumors
Search

PRAME

0.96	Melanoma antigen preferentially expressed in tumors

0.79	GO:0045596	negative regulation of cell differentiation
0.79	GO:0008284	positive regulation of cell proliferation
0.78	GO:0043066	negative regulation of apoptotic process
0.72	GO:0045892	negative regulation of transcription, DNA-templated
0.60	GO:0048387	negative regulation of retinoic acid receptor signaling pathway
0.39	GO:0040008	regulation of growth
0.39	GO:0006915	apoptotic process
0.38	GO:0030154	cell differentiation
0.35	GO:0006351	transcription, DNA-templated

0.59

GO:0042974

retinoic acid receptor binding

0.36	GO:0005634	nucleus
0.35	GO:0005886	plasma membrane

sp|P78396|CCNA1_HUMAN
Cyclin-A1
Search

0.86	Testicular tissue protein Li 34

0.47	GO:0000086	G2/M transition of mitotic cell cycle
0.47	GO:0044843	cell cycle G1/S phase transition
0.47	GO:0016572	histone phosphorylation
0.46	GO:0007265	Ras protein signal transduction
0.43	GO:0045893	positive regulation of transcription, DNA-templated
0.43	GO:0051726	regulation of cell cycle
0.40	GO:0007423	sensory organ development
0.37	GO:0051301	cell division
0.37	GO:0007283	spermatogenesis
0.36	GO:0051321	meiotic cell cycle

0.46	GO:0097472	cyclin-dependent protein kinase activity
0.44	GO:0019901	protein kinase binding
0.44	GO:0019904	protein domain specific binding
0.34	GO:0001103	RNA polymerase II repressing transcription factor binding

0.61	GO:0005634	nucleus
0.58	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.49	GO:0015630	microtubule cytoskeleton
0.42	GO:0005829	cytosol
0.42	GO:0031974	membrane-enclosed lumen
0.39	GO:0044446	intracellular organelle part
0.34	GO:0001750	photoreceptor outer segment
0.34	GO:0034464	BBSome
0.33	GO:0097014	ciliary plasm
0.30	GO:0016020	membrane

sp|P78406|RAE1L_HUMAN
mRNA export factor
Search

RAE1

0.93	mRNA export factor

0.81	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.76	GO:0051028	mRNA transport
0.75	GO:0006405	RNA export from nucleus
0.55	GO:0060236	regulation of mitotic spindle organization
0.54	GO:0010467	gene expression
0.51	GO:0071407	cellular response to organic cyclic compound
0.50	GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery
0.47	GO:0006606	protein import into nucleus
0.39	GO:0007049	cell cycle
0.39	GO:0051301	cell division

0.48	GO:0043130	ubiquitin binding
0.44	GO:0003723	RNA binding
0.35	GO:0008017	microtubule binding
0.35	GO:0016905	myosin heavy chain kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0003677	DNA binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.57	GO:0097431	mitotic spindle pole
0.54	GO:0001650	fibrillar center
0.53	GO:0005643	nuclear pore
0.35	GO:0005737	cytoplasm
0.33	GO:0005694	chromosome
0.33	GO:0044215	other organism

0.35

EC:2.7.11.7

GO:0016905

sp|P78410|BT3A2_HUMAN
Butyrophilin subfamily 3 member A2
Search

0.73	Butyrophilin subfamily 3 member A2 isoform a

0.51	GO:0002456	T cell mediated immunity
0.46	GO:0072643	interferon-gamma secretion
0.40	GO:0046007	negative regulation of activated T cell proliferation
0.39	GO:0050710	negative regulation of cytokine secretion
0.39	GO:0050798	activated T cell proliferation
0.39	GO:0002684	positive regulation of immune system process
0.38	GO:0050776	regulation of immune response
0.38	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling
0.38	GO:0045589	regulation of regulatory T cell differentiation
0.37	GO:0051898	negative regulation of protein kinase B signaling

0.36

GO:0005515

protein binding

0.41	GO:0005886	plasma membrane
0.36	GO:0009986	cell surface
0.35	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

sp|P78411|IRX5_HUMAN
Iroquois-class homeodomain protein IRX-5
Search

IRX5

0.91	Iroquois-class homeodomain protein IRX-5

0.66	GO:0060040	retinal bipolar neuron differentiation
0.64	GO:0048706	embryonic skeletal system development
0.62	GO:1904888	cranial skeletal system development
0.62	GO:0042551	neuron maturation
0.61	GO:0002027	regulation of heart rate
0.61	GO:0008406	gonad development
0.61	GO:0048705	skeletal system morphogenesis
0.60	GO:0048562	embryonic organ morphogenesis
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription

0.64	GO:0043565	sequence-specific DNA binding
0.38	GO:0005499	vitamin D binding
0.33	GO:0003723	RNA binding

0.61	GO:0005634	nucleus
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P78412|IRX6_HUMAN
Iroquois-class homeodomain protein IRX-6
Search

IRX6

0.89	Iroquois homeobox protein 2, a

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0072086	specification of loop of Henle identity
0.56	GO:0010468	regulation of gene expression
0.53	GO:0001656	metanephros development
0.47	GO:0048523	negative regulation of cellular process
0.45	GO:0010558	negative regulation of macromolecule biosynthetic process
0.45	GO:0007498	mesoderm development
0.45	GO:0051961	negative regulation of nervous system development
0.44	GO:0045666	positive regulation of neuron differentiation

0.65	GO:0043565	sequence-specific DNA binding
0.38	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.38	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.44	GO:0030424	axon
0.35	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P78413|IRX4_HUMAN
Iroquois-class homeodomain protein IRX-4
Search

IRX4

0.89	Iroquois-class homeodomain protein irx-4-B

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:0007507	heart development
0.56	GO:0010468	regulation of gene expression
0.44	GO:0048561	establishment of animal organ orientation
0.44	GO:0048924	posterior lateral line neuromast mantle cell differentiation
0.43	GO:0048923	posterior lateral line neuromast hair cell differentiation
0.41	GO:0042461	photoreceptor cell development
0.37	GO:0045317	equator specification
0.37	GO:0097374	sensory neuron axon guidance

0.64	GO:0043565	sequence-specific DNA binding
0.35	GO:0042803	protein homodimerization activity
0.35	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.36	GO:0005667	transcription factor complex
0.34	GO:0030424	axon
0.32	GO:0005737	cytoplasm

sp|P78414|IRX1_HUMAN
Iroquois-class homeodomain protein IRX-1
Search

IRX1

0.95	Iroquois-class homeodomain protein irx-1-A

0.57	GO:0072081	specification of nephron tubule identity
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:0072272	proximal/distal pattern formation involved in metanephric nephron development
0.56	GO:0010468	regulation of gene expression
0.55	GO:0072070	loop of Henle development
0.50	GO:1902679	negative regulation of RNA biosynthetic process
0.48	GO:0035118	embryonic pectoral fin morphogenesis
0.47	GO:0007417	central nervous system development
0.46	GO:0031076	embryonic camera-type eye development

0.64	GO:0043565	sequence-specific DNA binding
0.37	GO:0044212	transcription regulatory region DNA binding
0.36	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.34	GO:0003723	RNA binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|P78415|IRX3_HUMAN
Iroquois-class homeodomain protein IRX-3
Search

0.83	iroquois-class homeodomain protein IRX-3

0.60	GO:0072086	specification of loop of Henle identity
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0001656	metanephros development
0.50	GO:0045665	negative regulation of neuron differentiation
0.50	GO:0007498	mesoderm development
0.50	GO:0045666	positive regulation of neuron differentiation
0.44	GO:1902679	negative regulation of RNA biosynthetic process
0.43	GO:0031018	endocrine pancreas development

0.64	GO:0043565	sequence-specific DNA binding
0.35	GO:0004969	histamine receptor activity
0.35	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.34	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.49	GO:0030424	axon
0.37	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P78417|GSTO1_HUMAN
Glutathione S-transferase omega-1
Search

GSTO1

0.88	Glutathione S-transferase omega-1

0.61	GO:0071243	cellular response to arsenic-containing substance
0.59	GO:0019852	L-ascorbic acid metabolic process
0.55	GO:0006805	xenobiotic metabolic process
0.54	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity
0.53	GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity
0.53	GO:0098754	detoxification
0.53	GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
0.50	GO:0097237	cellular response to toxic substance
0.49	GO:0090487	secondary metabolite catabolic process
0.49	GO:0006749	glutathione metabolic process

0.79	GO:0004364	glutathione transferase activity
0.63	GO:0045174	glutathione dehydrogenase (ascorbate) activity
0.46	GO:0042802	identical protein binding
0.44	GO:0050610	methylarsonate reductase activity

0.49	GO:0005737	cytoplasm
0.38	GO:0070062	extracellular exosome
0.35	GO:0043209	myelin sheath
0.35	GO:0005604	basement membrane
0.34	GO:0044297	cell body
0.34	GO:0030424	axon
0.34	GO:0031965	nuclear membrane

0.79	EC:2.5.1.18	GO:0004364
0.63	KEGG:R01108	GO:0045174

sp|P78423|X3CL1_HUMAN
Fractalkine
Search

CX3CL1

0.85	Fractalkine

0.88	GO:0050902	leukocyte adhesive activation
0.82	GO:0060326	cell chemotaxis
0.80	GO:0019221	cytokine-mediated signaling pathway
0.74	GO:0006955	immune response
0.71	GO:0051041	positive regulation of calcium-independent cell-cell adhesion
0.65	GO:0032914	positive regulation of transforming growth factor beta1 production
0.64	GO:0033622	integrin activation
0.64	GO:0002523	leukocyte migration involved in inflammatory response
0.63	GO:1905517	macrophage migration
0.63	GO:0050729	positive regulation of inflammatory response

0.84	GO:0008009	chemokine activity
0.67	GO:0031737	CX3C chemokine receptor binding
0.60	GO:0005178	integrin binding
0.56	GO:0048020	CCR chemokine receptor binding

0.66	GO:0005576	extracellular region
0.58	GO:0009986	cell surface
0.42	GO:0048471	perinuclear region of cytoplasm
0.41	GO:0005886	plasma membrane
0.41	GO:0098794	postsynapse
0.39	GO:0042995	cell projection
0.30	GO:0016021	integral component of membrane

sp|P78424|PO6F2_HUMAN
POU domain, class 6, transcription factor 2
Search

0.44	POU domain, class 6, transcription factor 2

0.75	GO:0006366	transcription by RNA polymerase II
0.70	GO:0007275	multicellular organism development
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.52	GO:0031099	regeneration
0.34	GO:0120039	plasma membrane bounded cell projection morphogenesis
0.34	GO:0007600	sensory perception
0.34	GO:0000904	cell morphogenesis involved in differentiation
0.34	GO:0120036	plasma membrane bounded cell projection organization

0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0003677	DNA binding
0.37	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|P78426|NKX61_HUMAN
Homeobox protein Nkx-6.1
Search

NKX6-1

0.96	Homeobox protein Nkx-6.1

0.78	GO:0031018	endocrine pancreas development
0.77	GO:0035883	enteroendocrine cell differentiation
0.74	GO:0030516	regulation of axon extension
0.73	GO:0001764	neuron migration
0.73	GO:0050796	regulation of insulin secretion
0.66	GO:0021522	spinal cord motor neuron differentiation
0.64	GO:0021913	regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification
0.62	GO:0045686	negative regulation of glial cell differentiation
0.62	GO:0045687	positive regulation of glial cell differentiation
0.60	GO:0048709	oligodendrocyte differentiation

0.64	GO:0043565	sequence-specific DNA binding
0.56	GO:0003700	DNA binding transcription factor activity
0.45	GO:0001012	RNA polymerase II regulatory region DNA binding
0.43	GO:0003690	double-stranded DNA binding
0.39	GO:0003682	chromatin binding
0.32	GO:0003924	GTPase activity
0.32	GO:0005525	GTP binding

0.61	GO:0005634	nucleus
0.38	GO:0070062	extracellular exosome
0.34	GO:0005829	cytosol
0.32	GO:0005874	microtubule

sp|P78504|JAG1_HUMAN
Protein jagged-1
Search

sp|P78508|KCJ10_HUMAN
ATP-sensitive inward rectifier potassium channel 10
Search

KCNJ10

0.96	Potassium inwardly-rectifying channel

0.78	GO:0034765	regulation of ion transmembrane transport
0.71	GO:0006813	potassium ion transport
0.61	GO:0098655	cation transmembrane transport
0.57	GO:0051933	amino acid neurotransmitter reuptake
0.56	GO:0060075	regulation of resting membrane potential
0.55	GO:0098712	L-glutamate import across plasma membrane
0.54	GO:0022010	central nervous system myelination
0.54	GO:0048169	regulation of long-term neuronal synaptic plasticity
0.54	GO:0007628	adult walking behavior
0.52	GO:0055075	potassium ion homeostasis

0.84	GO:0005242	inward rectifier potassium channel activity
0.35	GO:0005515	protein binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.51	GO:0016323	basolateral plasma membrane
0.50	GO:0098793	presynapse
0.42	GO:0005887	integral component of plasma membrane
0.35	GO:0097449	astrocyte projection
0.35	GO:0005902	microvillus
0.35	GO:0016324	apical plasma membrane

sp|P78509|RELN_HUMAN
Reelin
Search

RELN

0.59

Reelin

0.84	GO:0001764	neuron migration
0.78	GO:0007417	central nervous system development
0.53	GO:1902076	regulation of lateral motor column neuron migration
0.52	GO:1905485	positive regulation of motor neuron migration
0.52	GO:0097114	NMDA glutamate receptor clustering
0.52	GO:0097119	postsynaptic density protein 95 clustering
0.52	GO:2000969	positive regulation of AMPA receptor activity
0.52	GO:0090129	positive regulation of synapse maturation
0.52	GO:0061003	positive regulation of dendritic spine morphogenesis
0.52	GO:1900273	positive regulation of long-term synaptic potentiation

0.85	GO:0070325	lipoprotein particle receptor binding
0.43	GO:0015116	sulfate transmembrane transporter activity
0.33	GO:0017171	serine hydrolase activity
0.33	GO:0070011	peptidase activity, acting on L-amino acid peptides
0.32	GO:0046872	metal ion binding
0.32	GO:0015291	secondary active transmembrane transporter activity

0.48	GO:0030425	dendrite
0.46	GO:0005578	proteinaceous extracellular matrix
0.45	GO:0005615	extracellular space
0.39	GO:0005886	plasma membrane
0.37	GO:0005737	cytoplasm
0.33	GO:0043204	perikaryon
0.32	GO:0030424	axon
0.30	GO:0016021	integral component of membrane

sp|P78524|ST5_HUMAN
Suppression of tumorigenicity 5 protein
Search

ST5

0.95	Suppression of tumorigenicity 5

0.66	GO:0065009	regulation of molecular function
0.47	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.35	GO:0055114	oxidation-reduction process

0.84	GO:0017112	Rab guanyl-nucleotide exchange factor activity
0.37	GO:0016651	oxidoreductase activity, acting on NAD(P)H
0.32	GO:0046872	metal ion binding

0.31	GO:0005622	intracellular
0.30	GO:0031224	intrinsic component of membrane

0.37

EC:1.6

GO:0016651

sp|P78527|PRKDC_HUMAN
DNA-dependent protein kinase catalytic subunit
Search

PRKDC

0.85	DNA-dependent protein kinase catalytic subunit

0.80	GO:0006303	double-strand break repair via nonhomologous end joining
0.66	GO:1902400	intracellular signal transduction involved in G1 DNA damage checkpoint
0.65	GO:0002328	pro-B cell differentiation
0.65	GO:0002326	B cell lineage commitment
0.65	GO:1902402	signal transduction involved in mitotic DNA damage checkpoint
0.65	GO:0033152	immunoglobulin V(D)J recombination
0.64	GO:0031571	mitotic G1 DNA damage checkpoint
0.64	GO:0035234	ectopic germ cell programmed cell death
0.63	GO:0002568	somatic diversification of T cell receptor genes
0.63	GO:0002360	T cell lineage commitment

0.86	GO:0004677	DNA-dependent protein kinase activity
0.57	GO:0019904	protein domain specific binding
0.55	GO:0008134	transcription factor binding
0.54	GO:0030554	adenyl nucleotide binding
0.54	GO:0003677	DNA binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.53	GO:0019899	enzyme binding
0.35	GO:0003723	RNA binding

0.66	GO:0070419	nonhomologous end joining complex
0.61	GO:0005634	nucleus
0.56	GO:0005667	transcription factor complex
0.54	GO:0032993	protein-DNA complex
0.52	GO:0070013	intracellular organelle lumen
0.48	GO:0043232	intracellular non-membrane-bounded organelle
0.47	GO:0044446	intracellular organelle part
0.39	GO:0031012	extracellular matrix
0.35	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.86

GO:0004677

sp|P78536|ADA17_HUMAN
Disintegrin and metalloproteinase domain-containing protein 17
Search

ADAM17

0.97	Tumor necrosis factor-alpha-converting enzyme

0.64	GO:0007229	integrin-mediated signaling pathway
0.61	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis
0.61	GO:0071403	cellular response to high density lipoprotein particle stimulus
0.61	GO:0035625	epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway
0.60	GO:0031659	positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle
0.60	GO:0010820	positive regulation of T cell chemotaxis
0.59	GO:0035313	wound healing, spreading of epidermal cells
0.59	GO:0007220	Notch receptor processing
0.58	GO:0033627	cell adhesion mediated by integrin
0.57	GO:0007173	epidermal growth factor receptor signaling pathway

0.70	GO:0004222	metalloendopeptidase activity
0.59	GO:0005138	interleukin-6 receptor binding
0.58	GO:0005112	Notch binding
0.57	GO:0030165	PDZ domain binding
0.56	GO:0005178	integrin binding
0.53	GO:0046872	metal ion binding
0.38	GO:0017124	SH3 domain binding
0.34	GO:0004252	serine-type endopeptidase activity

0.57	GO:0032587	ruffle membrane
0.55	GO:0005925	focal adhesion
0.55	GO:0016324	apical plasma membrane
0.54	GO:0098857	membrane microdomain
0.52	GO:0005911	cell-cell junction
0.52	GO:0009986	cell surface
0.51	GO:0015629	actin cytoskeleton
0.49	GO:0005829	cytosol
0.48	GO:0005887	integral component of plasma membrane
0.35	GO:0005615	extracellular space

0.70

GO:0004222

sp|P78537|BL1S1_HUMAN
Biogenesis of lysosome-related organelles complex 1 subunit 1
Search

BLOC1S1

0.95	Biogenesis of lysosomal organelles complex 1 subunit 1

0.50	GO:0048490	anterograde synaptic vesicle transport
0.46	GO:0016197	endosomal transport
0.42	GO:0032418	lysosome localization
0.41	GO:0048753	pigment granule organization
0.40	GO:0031175	neuron projection development
0.40	GO:0018394	peptidyl-lysine acetylation
0.39	GO:0008355	olfactory learning
0.39	GO:0007274	neuromuscular synaptic transmission
0.39	GO:0036465	synaptic vesicle recycling
0.38	GO:0050808	synapse organization

0.34	GO:0005515	protein binding
0.34	GO:0008478	pyridoxal kinase activity

0.84	GO:0031083	BLOC-1 complex
0.49	GO:1904115	axon cytoplasm
0.47	GO:0005758	mitochondrial intermembrane space
0.46	GO:0005769	early endosome
0.45	GO:0005759	mitochondrial matrix
0.43	GO:0099078	BORC complex
0.41	GO:0005765	lysosomal membrane
0.37	GO:0045202	synapse
0.36	GO:0070062	extracellular exosome
0.35	GO:0005788	endoplasmic reticulum lumen

0.34

EC:2.7.1.35

GO:0008478

sp|P78539|SRPX_HUMAN
Sushi repeat-containing protein SRPX
Search

SRPX

0.97	Sushi repeat-containing protein SRPX

0.85	GO:0060244	negative regulation of cell proliferation involved in contact inhibition
0.85	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
0.84	GO:0001845	phagolysosome assembly
0.76	GO:0034976	response to endoplasmic reticulum stress
0.73	GO:0006914	autophagy
0.50	GO:0051965	positive regulation of synapse assembly
0.50	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis
0.48	GO:0071625	vocalization behavior
0.47	GO:0007155	cell adhesion
0.46	GO:0042325	regulation of phosphorylation

0.54	GO:0036458	hepatocyte growth factor binding
0.46	GO:0042802	identical protein binding
0.45	GO:0005102	receptor binding

0.80	GO:0005776	autophagosome
0.67	GO:0005783	endoplasmic reticulum
0.46	GO:0005615	extracellular space
0.41	GO:0009986	cell surface
0.38	GO:0060076	excitatory synapse
0.37	GO:0097060	synaptic membrane
0.36	GO:0030054	cell junction
0.30	GO:0016021	integral component of membrane

sp|P78540|ARGI2_HUMAN
Arginase-2, mitochondrial
Search

ARG2

0.57	Arginase-2, mitochondrial

0.85	GO:0000050	urea cycle
0.70	GO:0006525	arginine metabolic process
0.62	GO:0071643	regulation of chemokine (C-C motif) ligand 4 production
0.62	GO:1905403	negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process
0.62	GO:1905077	negative regulation of interleukin-17 secretion
0.62	GO:0071641	negative regulation of macrophage inflammatory protein 1 alpha production
0.61	GO:0002829	negative regulation of type 2 immune response
0.61	GO:2000666	negative regulation of interleukin-13 secretion
0.61	GO:0071650	negative regulation of chemokine (C-C motif) ligand 5 production
0.61	GO:2000562	negative regulation of CD4-positive, alpha-beta T cell proliferation

0.83	GO:0004053	arginase activity
0.54	GO:0046872	metal ion binding
0.35	GO:0050998	nitric-oxide synthase binding
0.33	GO:0003933	GTP cyclohydrolase activity

0.46	GO:0005739	mitochondrion
0.39	GO:0005615	extracellular space
0.35	GO:0035580	specific granule lumen
0.34	GO:0035578	azurophil granule lumen
0.34	GO:0043025	neuronal cell body
0.34	GO:1903561	extracellular vesicle
0.33	GO:0043005	neuron projection
0.33	GO:0031968	organelle outer membrane
0.33	GO:0005829	cytosol
0.32	GO:0005634	nucleus

0.83

EC:3.5.3.1

GO:0004053

sp|P78543|BTG2_HUMAN
Protein BTG2
Search

BTG2

0.94	B-cell translocation protein 1, anti-proliferative

0.79	GO:0008285	negative regulation of cell proliferation
0.57	GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
0.56	GO:0021542	dentate gyrus development
0.55	GO:0035914	skeletal muscle cell differentiation
0.55	GO:0008306	associative learning
0.54	GO:0021954	central nervous system neuron development
0.54	GO:2000177	regulation of neural precursor cell proliferation
0.53	GO:0009952	anterior/posterior pattern specification
0.52	GO:0031175	neuron projection development
0.51	GO:0017148	negative regulation of translation

0.44	GO:0019899	enzyme binding
0.39	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.34	GO:0003712	transcription cofactor activity

0.41	GO:0005634	nucleus
0.37	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome

sp|P78545|ELF3_HUMAN
ETS-related transcription factor Elf-3
Search

ELF3

0.96	ETS-related transcription factor Elf-3

0.79	GO:0006954	inflammatory response
0.78	GO:0030855	epithelial cell differentiation
0.75	GO:0006366	transcription by RNA polymerase II
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.45	GO:0060056	mammary gland involution
0.44	GO:0001824	blastocyst development
0.42	GO:1902680	positive regulation of RNA biosynthetic process
0.42	GO:0030198	extracellular matrix organization

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.42	GO:0001012	RNA polymerase II regulatory region DNA binding
0.42	GO:0003713	transcription coactivator activity
0.41	GO:0003690	double-stranded DNA binding
0.35	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.42	GO:0005794	Golgi apparatus
0.41	GO:0005829	cytosol
0.41	GO:0031974	membrane-enclosed lumen
0.38	GO:0044446	intracellular organelle part

sp|P78549|NTH_HUMAN
Endonuclease III-like protein 1
Search

NTHL1

0.97	Nth like DNA glycosylase 1

0.82	GO:0006285	base-excision repair, AP site formation
0.61	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion
0.36	GO:0009223	pyrimidine deoxyribonucleotide catabolic process
0.34	GO:0006304	DNA modification
0.32	GO:0035556	intracellular signal transduction

0.75	GO:0000703	oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity
0.74	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity
0.64	GO:0051539	4 iron, 4 sulfur cluster binding
0.57	GO:0004519	endonuclease activity
0.55	GO:0003677	DNA binding
0.49	GO:0046872	metal ion binding
0.35	GO:0008534	oxidized purine nucleobase lesion DNA N-glycosylase activity
0.34	GO:0005515	protein binding

0.59	GO:0005634	nucleus
0.55	GO:0005739	mitochondrion
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part

0.74

EC:4.2.99.18

GO:0003906

sp|P78552|I13R1_HUMAN
Interleukin-13 receptor subunit alpha-1
Search

IL13RA1

0.97	Interleukin-13 receptor subunit alpha-1

0.79	GO:0019221	cytokine-mediated signaling pathway
0.41	GO:0035963	cellular response to interleukin-13
0.40	GO:0002639	positive regulation of immunoglobulin production
0.40	GO:0030890	positive regulation of B cell proliferation

0.81	GO:0004896	cytokine receptor activity
0.35	GO:0005515	protein binding

0.41

GO:0005898

interleukin-13 receptor complex

sp|P78556|CCL20_HUMAN
C-C motif chemokine 20
Search

CCL20

0.70	C-C motif chemokine

0.82	GO:0060326	cell chemotaxis
0.74	GO:0006955	immune response
0.74	GO:0010469	regulation of receptor activity
0.73	GO:0072679	thymocyte migration
0.69	GO:2000406	positive regulation of T cell migration
0.69	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.56	GO:0071674	mononuclear cell migration
0.55	GO:1990266	neutrophil migration
0.55	GO:0071347	cellular response to interleukin-1
0.54	GO:0071356	cellular response to tumor necrosis factor

0.84	GO:0008009	chemokine activity
0.73	GO:0031731	CCR6 chemokine receptor binding

0.72	GO:0005615	extracellular space
0.40	GO:0005622	intracellular
0.30	GO:0016020	membrane

sp|P78559|MAP1A_HUMAN
Microtubule-associated protein 1A
Search

MAP1A

0.87	Microtubule-associated protein 1A

0.76	GO:0000226	microtubule cytoskeleton organization
0.39	GO:0045494	photoreceptor cell maintenance
0.39	GO:0007605	sensory perception of sound
0.36	GO:0007026	negative regulation of microtubule depolymerization

0.74	GO:0008017	microtubule binding
0.37	GO:0005198	structural molecule activity
0.35	GO:0005518	collagen binding
0.34	GO:0003779	actin binding

0.73	GO:0005874	microtubule
0.40	GO:0005875	microtubule associated complex
0.39	GO:0001750	photoreceptor outer segment
0.39	GO:0014069	postsynaptic density
0.36	GO:0005829	cytosol
0.35	GO:0030425	dendrite
0.35	GO:0030424	axon

sp|P78560|CRADD_HUMAN
Death domain-containing protein CRADD
Search

CRADD

0.89	Death domain-containing protein CRADD

0.73	GO:0042981	regulation of apoptotic process
0.56	GO:0007165	signal transduction
0.48	GO:0071158	positive regulation of cell cycle arrest
0.48	GO:0031571	mitotic G1 DNA damage checkpoint
0.48	GO:0071260	cellular response to mechanical stimulus
0.46	GO:2001056	positive regulation of cysteine-type endopeptidase activity
0.46	GO:0043068	positive regulation of programmed cell death
0.43	GO:0009967	positive regulation of signal transduction
0.42	GO:0006915	apoptotic process
0.37	GO:0046426	negative regulation of JAK-STAT cascade

0.86	GO:0070513	death domain binding
0.82	GO:0002020	protease binding
0.47	GO:0030674	protein binding, bridging
0.38	GO:0005159	insulin-like growth factor receptor binding
0.37	GO:0035591	signaling adaptor activity

0.39	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm

sp|P78562|PHEX_HUMAN
Phosphate-regulating neutral endopeptidase
Search

PHEX

0.49	Phosphate-regulating neutral endopeptidase

0.61	GO:0006508	proteolysis
0.59	GO:0030282	bone mineralization
0.44	GO:0019637	organophosphate metabolic process
0.44	GO:1904383	response to sodium phosphate
0.43	GO:1990418	response to insulin-like growth factor stimulus
0.43	GO:0071374	cellular response to parathyroid hormone stimulus
0.42	GO:0071305	cellular response to vitamin D
0.42	GO:0060416	response to growth hormone
0.41	GO:0030324	lung development
0.41	GO:0060348	bone development

0.70	GO:0004222	metalloendopeptidase activity
0.34	GO:0004177	aminopeptidase activity
0.33	GO:0046872	metal ion binding
0.33	GO:0016740	transferase activity

0.54	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0005794	Golgi apparatus
0.50	GO:0005783	endoplasmic reticulum
0.34	GO:0005887	integral component of plasma membrane

0.70

GO:0004222

sp|P78563|RED1_HUMAN
Double-stranded RNA-specific editase 1
Search

ADARB1

0.73	Double-stranded RNA-specific editase 1

0.62	GO:0006396	RNA processing
0.59	GO:0021618	hypoglossal nerve morphogenesis
0.59	GO:0097049	motor neuron apoptotic process
0.58	GO:0021965	spinal cord ventral commissure morphogenesis
0.58	GO:0061744	motor behavior
0.57	GO:0044387	negative regulation of protein kinase activity by regulation of protein phosphorylation
0.57	GO:0021610	facial nerve morphogenesis
0.56	GO:0050884	neuromuscular process controlling posture
0.56	GO:0060384	innervation
0.56	GO:0045070	positive regulation of viral genome replication

0.77	GO:0004000	adenosine deaminase activity
0.59	GO:0003723	RNA binding
0.38	GO:0005515	protein binding
0.36	GO:0046872	metal ion binding

0.49	GO:0005730	nucleolus
0.48	GO:0005654	nucleoplasm
0.47	GO:0005829	cytosol

0.77

EC:3.5.4.4

GO:0004000

sp|P79483|DRB3_HUMAN
HLA class II histocompatibility antigen, DR beta 3 chain
Search

0.55	HLA class II histocompatibility antigen, DR beta 3 chain

0.83	GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
0.74	GO:0006955	immune response
0.70	GO:0002478	antigen processing and presentation of exogenous peptide antigen
0.70	GO:0031295	T cell costimulation
0.68	GO:0050852	T cell receptor signaling pathway
0.64	GO:2001179	regulation of interleukin-10 secretion
0.63	GO:0019221	cytokine-mediated signaling pathway
0.62	GO:0032673	regulation of interleukin-4 production
0.62	GO:0032689	negative regulation of interferon-gamma production
0.62	GO:0016045	detection of bacterium

0.67	GO:0042605	peptide antigen binding
0.62	GO:0032395	MHC class II receptor activity
0.47	GO:0023026	MHC class II protein complex binding
0.46	GO:0001618	virus receptor activity
0.44	GO:0042609	CD4 receptor binding

0.76	GO:0042613	MHC class II protein complex
0.69	GO:0071556	integral component of lumenal side of endoplasmic reticulum membrane
0.68	GO:0032588	trans-Golgi network membrane
0.67	GO:0030669	clathrin-coated endocytic vesicle membrane
0.65	GO:0031902	late endosome membrane
0.65	GO:0005765	lysosomal membrane
0.63	GO:0012507	ER to Golgi transport vesicle membrane
0.58	GO:0009897	external side of plasma membrane
0.47	GO:0005615	extracellular space
0.45	GO:0005887	integral component of plasma membrane

sp|P79522|PRR3_HUMAN
Proline-rich protein 3
Search

PRR3

0.95	Proline-rich protein 3

0.54	GO:0046872	metal ion binding
0.39	GO:0003723	RNA binding
0.38	GO:0005515	protein binding

sp|P80075|CCL8_HUMAN
C-C motif chemokine 8
Search

0.74	C-C motif chemokine

0.82	GO:0060326	cell chemotaxis
0.74	GO:0006955	immune response
0.72	GO:0010469	regulation of receptor activity
0.65	GO:0097529	myeloid leukocyte migration
0.59	GO:0071674	mononuclear cell migration
0.59	GO:0071347	cellular response to interleukin-1
0.58	GO:0071356	cellular response to tumor necrosis factor
0.56	GO:0006954	inflammatory response
0.56	GO:2000501	regulation of natural killer cell chemotaxis
0.55	GO:0019221	cytokine-mediated signaling pathway

0.84	GO:0008009	chemokine activity
0.61	GO:0048020	CCR chemokine receptor binding
0.51	GO:0016004	phospholipase activator activity
0.42	GO:0004672	protein kinase activity
0.42	GO:0008201	heparin binding
0.40	GO:0046983	protein dimerization activity
0.33	GO:0031737	CX3C chemokine receptor binding
0.33	GO:0005178	integrin binding

0.70	GO:0005615	extracellular space
0.36	GO:0044299	C-fiber
0.36	GO:0005622	intracellular
0.36	GO:0043204	perikaryon
0.35	GO:0043679	axon terminus
0.35	GO:0030425	dendrite
0.34	GO:0031982	vesicle
0.34	GO:0012505	endomembrane system
0.32	GO:0009986	cell surface
0.30	GO:0044425	membrane part

sp|P80098|CCL7_HUMAN
C-C motif chemokine 7
Search

0.74	C-C motif chemokine

0.82	GO:0060326	cell chemotaxis
0.74	GO:0006955	immune response
0.73	GO:0010469	regulation of receptor activity
0.65	GO:0097529	myeloid leukocyte migration
0.60	GO:0071674	mononuclear cell migration
0.59	GO:2000501	regulation of natural killer cell chemotaxis
0.58	GO:0071347	cellular response to interleukin-1
0.57	GO:0071356	cellular response to tumor necrosis factor
0.57	GO:0006954	inflammatory response
0.55	GO:0019221	cytokine-mediated signaling pathway

0.84	GO:0008009	chemokine activity
0.62	GO:0048020	CCR chemokine receptor binding
0.48	GO:0016004	phospholipase activator activity
0.40	GO:0046983	protein dimerization activity
0.40	GO:0004672	protein kinase activity
0.40	GO:0008201	heparin binding

0.71	GO:0005615	extracellular space
0.36	GO:0005622	intracellular

sp|P80108|PHLD_HUMAN
Phosphatidylinositol-glycan-specific phospholipase D
Search

GPLD1

0.97	Glycosylphosphatidylinositol-specific phospholipase D

0.69	GO:0071401	cellular response to triglyceride
0.69	GO:0006507	GPI anchor release
0.67	GO:0045919	positive regulation of cytolysis
0.67	GO:0071397	cellular response to cholesterol
0.66	GO:0002042	cell migration involved in sprouting angiogenesis
0.66	GO:0002430	complement receptor mediated signaling pathway
0.66	GO:0051044	positive regulation of membrane protein ectodomain proteolysis
0.64	GO:0071277	cellular response to calcium ion
0.64	GO:0008286	insulin receptor signaling pathway
0.63	GO:1900076	regulation of cellular response to insulin stimulus

0.87	GO:0004621	glycosylphosphatidylinositol phospholipase D activity
0.47	GO:0017080	sodium channel regulator activity
0.34	GO:0005515	protein binding

0.66	GO:0005576	extracellular region
0.45	GO:0043231	intracellular membrane-bounded organelle
0.41	GO:0005737	cytoplasm
0.40	GO:1990777	lipoprotein particle
0.37	GO:0031982	vesicle
0.37	GO:0098805	whole membrane
0.37	GO:0098588	bounding membrane of organelle
0.35	GO:0044446	intracellular organelle part
0.34	GO:0008305	integrin complex

0.87

EC:3.1.4.50

GO:0004621

sp|P80162|CXCL6_HUMAN
C-X-C motif chemokine 6
Search

0.82	Alveolar macrophage chemotactic factor

0.82	GO:0060326	cell chemotaxis
0.74	GO:0006955	immune response
0.72	GO:0010469	regulation of receptor activity
0.72	GO:0006952	defense response
0.57	GO:0032496	response to lipopolysaccharide
0.56	GO:0090023	positive regulation of neutrophil chemotaxis
0.54	GO:0002446	neutrophil mediated immunity
0.53	GO:1990266	neutrophil migration
0.53	GO:0042119	neutrophil activation
0.53	GO:0071310	cellular response to organic substance

0.84	GO:0008009	chemokine activity
0.55	GO:0045236	CXCR chemokine receptor binding
0.43	GO:0042802	identical protein binding
0.42	GO:0008201	heparin binding

0.70	GO:0005615	extracellular space
0.30	GO:0016020	membrane
0.30	GO:0005623	cell

sp|P80188|NGAL_HUMAN
Neutrophil gelatinase-associated lipocalin
Search

LCN2

0.92	Neutrophil gelatinase-associated lipocalin

0.53	GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand
0.51	GO:0045087	innate immune response
0.50	GO:0015891	siderophore transport
0.49	GO:0009615	response to virus
0.41	GO:0071345	cellular response to cytokine stimulus
0.40	GO:0010046	response to mycotoxin
0.40	GO:0055072	iron ion homeostasis
0.40	GO:0070207	protein homotrimerization
0.39	GO:0070301	cellular response to hydrogen peroxide
0.39	GO:0070555	response to interleukin-1

0.51	GO:0036094	small molecule binding
0.44	GO:0005506	iron ion binding
0.39	GO:0002020	protease binding
0.37	GO:0042803	protein homodimerization activity
0.35	GO:0004667	prostaglandin-D synthase activity
0.34	GO:0005501	retinoid binding

0.51	GO:0005615	extracellular space
0.39	GO:1903561	extracellular vesicle
0.39	GO:0035580	specific granule lumen
0.36	GO:0005829	cytosol

0.35	EC:5.3.99.2	GO:0004667
0.35	KEGG:R02266	GO:0004667

sp|P80192|M3K9_HUMAN
Mitogen-activated protein kinase kinase kinase 9
Search

MAP3K9

0.81	Mitogen-activated protein kinase kinase kinase

0.78	GO:0000186	activation of MAPKK activity
0.74	GO:0000165	MAPK cascade
0.69	GO:0043507	positive regulation of JUN kinase activity
0.67	GO:0031098	stress-activated protein kinase signaling cascade
0.56	GO:0046777	protein autophosphorylation
0.49	GO:0000187	activation of MAPK activity
0.41	GO:0043065	positive regulation of apoptotic process
0.40	GO:0008219	cell death
0.37	GO:0018108	peptidyl-tyrosine phosphorylation
0.34	GO:0006351	transcription, DNA-templated

0.78	GO:0004709	MAP kinase kinase kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.37	GO:0004713	protein tyrosine kinase activity
0.37	GO:0004708	MAP kinase kinase activity
0.35	GO:0042803	protein homodimerization activity

0.43	GO:0005622	intracellular
0.30	GO:0016020	membrane

0.78

EC:2.7.11 EC:2.7.11.25

GO:0004709

sp|P80217|IN35_HUMAN
Interferon-induced 35 kDa protein
Search

IFI35

0.65	Interferon induced protein 35

0.62	GO:0060333	interferon-gamma-mediated signaling pathway
0.55	GO:0006366	transcription by RNA polymerase II
0.45	GO:2001141	regulation of RNA biosynthetic process
0.40	GO:0060337	type I interferon signaling pathway
0.37	GO:0045355	negative regulation of interferon-alpha biosynthetic process
0.37	GO:0045358	negative regulation of interferon-beta biosynthetic process
0.37	GO:1902524	positive regulation of protein K48-linked ubiquitination
0.36	GO:0043043	peptide biosynthetic process
0.35	GO:0044267	cellular protein metabolic process
0.35	GO:0045824	negative regulation of innate immune response

0.55	GO:0003712	transcription cofactor activity
0.37	GO:0005515	protein binding
0.37	GO:0003723	RNA binding
0.36	GO:0003735	structural constituent of ribosome

0.55	GO:0005634	nucleus
0.38	GO:0005829	cytosol
0.36	GO:0005840	ribosome
0.35	GO:0043233	organelle lumen
0.34	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|P80294|MT1H_HUMAN
Metallothionein-1H
Search

0.75	Metallothionein-I, hippocampal

0.64	GO:0071294	cellular response to zinc ion
0.55	GO:0045926	negative regulation of growth
0.49	GO:0036018	cellular response to erythropoietin
0.48	GO:0071276	cellular response to cadmium ion
0.45	GO:0036015	response to interleukin-3
0.41	GO:0035690	cellular response to drug
0.38	GO:0071280	cellular response to copper ion
0.37	GO:0035924	cellular response to vascular endothelial growth factor stimulus
0.36	GO:0006875	cellular metal ion homeostasis
0.35	GO:0001775	cell activation

0.54	GO:0046872	metal ion binding
0.36	GO:0005515	protein binding
0.36	GO:0008144	drug binding
0.33	GO:0017056	structural constituent of nuclear pore

0.54	GO:0048471	perinuclear region of cytoplasm
0.46	GO:0005634	nucleus
0.34	GO:0005829	cytosol
0.32	GO:0012505	endomembrane system
0.32	GO:0031967	organelle envelope
0.32	GO:0043234	protein complex
0.30	GO:0016020	membrane

sp|P80297|MT1X_HUMAN
Metallothionein-1X
Search

0.77	Metallothionein-I, hippocampal

0.64	GO:0071294	cellular response to zinc ion
0.55	GO:0045926	negative regulation of growth
0.49	GO:0036018	cellular response to erythropoietin
0.48	GO:0071276	cellular response to cadmium ion
0.44	GO:0036015	response to interleukin-3
0.41	GO:0035690	cellular response to drug
0.40	GO:0046688	response to copper ion
0.39	GO:0007263	nitric oxide mediated signal transduction
0.39	GO:0097501	stress response to metal ion
0.38	GO:0006882	cellular zinc ion homeostasis

0.54	GO:0046872	metal ion binding
0.36	GO:0005515	protein binding
0.35	GO:0008144	drug binding

0.54	GO:0048471	perinuclear region of cytoplasm
0.47	GO:0005634	nucleus
0.35	GO:0005829	cytosol

sp|P80303|NUCB2_HUMAN
Nucleobindin-2
Search

NUCB2

0.93	DNA-binding protein NEFA

0.43	GO:0032094	response to food
0.36	GO:1990680	response to melanocyte-stimulating hormone
0.36	GO:0044752	response to human chorionic gonadotropin
0.36	GO:2000845	positive regulation of testosterone secretion
0.35	GO:0070093	negative regulation of glucagon secretion
0.35	GO:1901142	insulin metabolic process
0.35	GO:0043951	negative regulation of cAMP-mediated signaling
0.35	GO:0046321	positive regulation of fatty acid oxidation
0.35	GO:0032099	negative regulation of appetite
0.35	GO:0046627	negative regulation of insulin receptor signaling pathway

0.70	GO:0005509	calcium ion binding
0.35	GO:0003677	DNA binding
0.35	GO:0005164	tumor necrosis factor receptor binding

0.51	GO:0005640	nuclear outer membrane
0.45	GO:0005783	endoplasmic reticulum
0.39	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.36	GO:0070062	extracellular exosome
0.36	GO:0005794	Golgi apparatus
0.35	GO:0043204	perikaryon
0.34	GO:0005829	cytosol
0.33	GO:0031984	organelle subcompartment
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|P80365|DHI2_HUMAN
Corticosteroid 11-beta-dehydrogenase isozyme 2
Search

HSD11B2

0.97	Corticosteroid 11-beta-dehydrogenase isozyme 2

0.58	GO:0007565	female pregnancy
0.52	GO:0055114	oxidation-reduction process
0.43	GO:0008211	glucocorticoid metabolic process
0.42	GO:0002017	regulation of blood volume by renal aldosterone
0.41	GO:0032094	response to food
0.40	GO:0051384	response to glucocorticoid
0.40	GO:0032868	response to insulin
0.40	GO:0001666	response to hypoxia
0.37	GO:0042493	response to drug
0.37	GO:0033555	multicellular organismal response to stress

0.53	GO:0016491	oxidoreductase activity
0.40	GO:0005496	steroid binding
0.37	GO:0051287	NAD binding

0.40	GO:0005783	endoplasmic reticulum
0.35	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.34	GO:0031984	organelle subcompartment
0.32	GO:0031966	mitochondrial membrane
0.32	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

0.53

GO:0016491

sp|P80370|DLK1_HUMAN
Protein delta homolog 1
Search

DLK1

0.96	Delta like non-canonical Notch ligand 1

0.61	GO:0045746	negative regulation of Notch signaling pathway
0.42	GO:0030154	cell differentiation
0.42	GO:1905563	negative regulation of vascular endothelial cell proliferation
0.41	GO:0046852	positive regulation of bone remodeling
0.41	GO:0045124	regulation of bone resorption
0.41	GO:0030282	bone mineralization
0.41	GO:0045599	negative regulation of fat cell differentiation
0.41	GO:0035264	multicellular organism growth
0.40	GO:0048706	embryonic skeletal system development
0.40	GO:0032846	positive regulation of homeostatic process

0.69	GO:0005509	calcium ion binding
0.35	GO:0004872	receptor activity
0.35	GO:0004222	metalloendopeptidase activity
0.35	GO:0005515	protein binding
0.34	GO:0008270	zinc ion binding
0.33	GO:0001871	pattern binding
0.32	GO:0030246	carbohydrate binding

0.53	GO:0005615	extracellular space
0.40	GO:0009897	external side of plasma membrane
0.33	GO:0045177	apical part of cell
0.32	GO:1903561	extracellular vesicle
0.31	GO:0005622	intracellular
0.30	GO:0016021	integral component of membrane

0.35

GO:0004222

sp|P80404|GABT_HUMAN
4-aminobutyrate aminotransferase, mitochondrial
Search

ABAT

0.52	Mitochondrial 4-aminobutyrate aminotransferase

0.77	GO:0009448	gamma-aminobutyric acid metabolic process
0.58	GO:0048148	behavioral response to cocaine
0.42	GO:1904448	regulation of aspartate secretion
0.42	GO:0014053	negative regulation of gamma-aminobutyric acid secretion
0.42	GO:1902722	positive regulation of prolactin secretion
0.42	GO:0033602	negative regulation of dopamine secretion
0.41	GO:0070474	positive regulation of uterine smooth muscle contraction
0.41	GO:0097151	positive regulation of inhibitory postsynaptic potential
0.41	GO:0045915	positive regulation of catecholamine metabolic process
0.41	GO:0031652	positive regulation of heat generation

0.79	GO:0003867	4-aminobutyrate transaminase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.51	GO:0042803	protein homodimerization activity
0.43	GO:0047298	(S)-3-amino-2-methylpropionate transaminase activity
0.42	GO:0032145	succinate-semialdehyde dehydrogenase binding
0.37	GO:0051536	iron-sulfur cluster binding
0.35	GO:0046872	metal ion binding

0.60	GO:0032144	4-aminobutyrate transaminase complex
0.45	GO:0005739	mitochondrion
0.38	GO:0043005	neuron projection
0.38	GO:0070013	intracellular organelle lumen
0.36	GO:0070062	extracellular exosome
0.36	GO:0044446	intracellular organelle part
0.34	GO:0005829	cytosol
0.33	GO:0043234	protein complex

0.79	EC:2.6.1.19	GO:0003867
0.43	KEGG:R04188	GO:0047298

sp|P80511|S10AC_HUMAN
Protein S100-A12
Search

S100A12

0.97	Calcium-binding protein A9

0.63	GO:0006955	immune response
0.61	GO:0006952	defense response
0.58	GO:0050727	regulation of inflammatory response
0.57	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.57	GO:0009620	response to fungus
0.55	GO:0031640	killing of cells of other organism
0.54	GO:0006805	xenobiotic metabolic process
0.48	GO:0070488	neutrophil aggregation
0.47	GO:0030593	neutrophil chemotaxis
0.45	GO:0032103	positive regulation of response to external stimulus

0.74	GO:0050786	RAGE receptor binding
0.70	GO:0005509	calcium ion binding
0.63	GO:0035662	Toll-like receptor 4 binding
0.63	GO:0050544	arachidonic acid binding
0.53	GO:0008017	microtubule binding
0.48	GO:0008270	zinc ion binding
0.38	GO:0005507	copper ion binding
0.36	GO:0042803	protein homodimerization activity
0.36	GO:0016209	antioxidant activity
0.33	GO:0003743	translation initiation factor activity

0.47	GO:0005634	nucleus
0.43	GO:0005576	extracellular region
0.41	GO:0005737	cytoplasm
0.41	GO:0005856	cytoskeleton
0.41	GO:0030054	cell junction
0.40	GO:0070013	intracellular organelle lumen
0.38	GO:0031983	vesicle lumen
0.38	GO:0044446	intracellular organelle part
0.37	GO:0005886	plasma membrane
0.36	GO:0097708	intracellular vesicle

sp|P80723|BASP1_HUMAN
Brain acid soluble protein 1
Search

BASP1

0.97	Brain abundant membrane attached signal protein 1

0.71	GO:0072112	glomerular visceral epithelial cell differentiation
0.65	GO:0045892	negative regulation of transcription, DNA-templated
0.48	GO:0021762	substantia nigra development
0.45	GO:2001076	positive regulation of metanephric ureteric bud development
0.44	GO:0007356	thorax and anterior abdomen determination
0.44	GO:0060539	diaphragm development
0.43	GO:0072075	metanephric mesenchyme development
0.43	GO:0060231	mesenchymal to epithelial transition
0.43	GO:0060421	positive regulation of heart growth
0.42	GO:0008406	gonad development

0.72	GO:0003714	transcription corepressor activity
0.67	GO:0019904	protein domain specific binding
0.63	GO:0044212	transcription regulatory region DNA binding
0.41	GO:0051536	iron-sulfur cluster binding
0.39	GO:0005516	calmodulin binding
0.37	GO:0003796	lysozyme activity
0.37	GO:0016417	S-acyltransferase activity
0.35	GO:0003723	RNA binding
0.35	GO:0016407	acetyltransferase activity
0.35	GO:0046872	metal ion binding

0.71	GO:0008180	COP9 signalosome
0.66	GO:0016607	nuclear speck
0.65	GO:0030054	cell junction
0.53	GO:0030426	growth cone
0.52	GO:0005886	plasma membrane
0.46	GO:0005737	cytoplasm
0.44	GO:0070062	extracellular exosome
0.41	GO:0005856	cytoskeleton
0.39	GO:0048786	presynaptic active zone
0.39	GO:0098562	cytoplasmic side of membrane

0.37

EC:3.2.1.17

GO:0003796

sp|P80748|LV321_HUMAN
Immunoglobulin lambda variable 3-21
Search

0.85	Ig lambda chain V-III region LOI

0.81	GO:0002250	adaptive immune response
0.72	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis
0.71	GO:0038095	Fc-epsilon receptor signaling pathway
0.71	GO:0002377	immunoglobulin production
0.69	GO:0030449	regulation of complement activation
0.67	GO:0002449	lymphocyte mediated immunity
0.67	GO:0006956	complement activation
0.66	GO:0050900	leukocyte migration
0.59	GO:0006898	receptor-mediated endocytosis
0.51	GO:0006508	proteolysis

0.84	GO:0003823	antigen binding
0.57	GO:0004252	serine-type endopeptidase activity

0.69	GO:0005615	extracellular space
0.56	GO:1903561	extracellular vesicle
0.54	GO:0005886	plasma membrane

0.57

GO:0004252

sp|P81133|SIM1_HUMAN
Single-minded homolog 1
Search

SIM1

0.96	Single-minded like protein 1

0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0035295	tube development
0.54	GO:0072163	mesonephric epithelium development
0.48	GO:0007399	nervous system development
0.44	GO:0009880	embryonic pattern specification
0.43	GO:0060541	respiratory system development
0.40	GO:0051253	negative regulation of RNA metabolic process

0.65	GO:0046983	protein dimerization activity
0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding

0.61	GO:0005634	nucleus
0.40	GO:0005667	transcription factor complex
0.39	GO:0031974	membrane-enclosed lumen
0.37	GO:0044446	intracellular organelle part
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|P81172|HEPC_HUMAN
Hepcidin
Search

HAMP

0.96	Hepcidin antimicrobial peptide

0.76	GO:0006879	cellular iron ion homeostasis
0.66	GO:1904479	negative regulation of intestinal absorption
0.65	GO:0060586	multicellular organismal iron ion homeostasis
0.62	GO:0010039	response to iron ion
0.55	GO:0034760	negative regulation of iron ion transmembrane transport
0.49	GO:0042742	defense response to bacterium
0.45	GO:0010469	regulation of receptor activity
0.42	GO:0050832	defense response to fungus
0.42	GO:1903413	cellular response to bile acid
0.42	GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development

0.46	GO:0005179	hormone activity
0.41	GO:0097690	iron channel inhibitor activity
0.37	GO:0005507	copper ion binding

0.66	GO:0005576	extracellular region
0.41	GO:0045179	apical cortex
0.40	GO:0014704	intercalated disc
0.35	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|P81274|GPSM2_HUMAN
G-protein-signaling modulator 2
Search

GPSM2

0.89	G protein signaling modulator 2

0.68	GO:0050790	regulation of catalytic activity
0.54	GO:1905832	positive regulation of spindle assembly
0.54	GO:1904778	positive regulation of protein localization to cell cortex
0.54	GO:0051661	maintenance of centrosome location
0.54	GO:0031291	Ran protein signal transduction
0.51	GO:0000132	establishment of mitotic spindle orientation
0.51	GO:0060236	regulation of mitotic spindle organization
0.50	GO:0007052	mitotic spindle organization
0.35	GO:0051301	cell division
0.30	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0030695	GTPase regulator activity
0.52	GO:0001965	G-protein alpha-subunit binding
0.51	GO:0043621	protein self-association
0.51	GO:0070840	dynein complex binding
0.51	GO:0008022	protein C-terminus binding
0.48	GO:0019904	protein domain specific binding
0.47	GO:0042802	identical protein binding
0.33	GO:1901265	nucleoside phosphate binding
0.33	GO:0036094	small molecule binding

0.54	GO:0097575	lateral cell cortex
0.52	GO:0097431	mitotic spindle pole
0.49	GO:0005813	centrosome
0.45	GO:0005829	cytosol
0.41	GO:0043234	protein complex
0.37	GO:0016328	lateral plasma membrane

sp|P81277|PRRP_HUMAN
Prolactin-releasing peptide
Search

PRLH

0.97	Prolactin releasing hormone

0.76	GO:0010469	regulation of receptor activity
0.73	GO:0002021	response to dietary excess
0.73	GO:0042755	eating behavior
0.71	GO:0048483	autonomic nervous system development
0.70	GO:0045444	fat cell differentiation
0.70	GO:0009749	response to glucose
0.70	GO:0040014	regulation of multicellular organism growth
0.69	GO:0032868	response to insulin
0.69	GO:0001894	tissue homeostasis
0.63	GO:0006112	energy reserve metabolic process

0.79	GO:0005179	hormone activity
0.52	GO:0031861	prolactin-releasing peptide receptor binding
0.39	GO:0017137	Rab GTPase binding
0.39	GO:0005148	prolactin receptor binding

0.41	GO:0005576	extracellular region
0.37	GO:0005737	cytoplasm

sp|P81408|F189B_HUMAN
Protein FAM189B
Search

0.61

GO:0050699

WW domain binding

0.30

GO:0044425

membrane part

sp|P81534|D103A_HUMAN
Beta-defensin 103
Search

0.93	Prepro-beta-defensin 3

0.72	GO:0006952	defense response
0.60	GO:0009617	response to bacterium
0.57	GO:0050918	positive chemotaxis
0.54	GO:0060326	cell chemotaxis
0.44	GO:0031640	killing of cells of other organism
0.42	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.40	GO:0060474	positive regulation of flagellated sperm motility involved in capacitation
0.39	GO:0035584	calcium-mediated signaling using intracellular calcium source
0.38	GO:0019933	cAMP-mediated signaling
0.38	GO:0009620	response to fungus

0.58	GO:0042056	chemoattractant activity
0.43	GO:0031731	CCR6 chemokine receptor binding
0.37	GO:0042802	identical protein binding

0.66	GO:0005576	extracellular region
0.40	GO:0005796	Golgi lumen
0.39	GO:0097225	sperm midpiece
0.37	GO:0019898	extrinsic component of membrane
0.37	GO:0031982	vesicle

sp|P81605|DCD_HUMAN
Dermcidin
Search

DCD

0.97

Dermcidin

0.79	GO:0031640	killing of cells of other organism
0.61	GO:0006508	proteolysis
0.48	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.46	GO:0050830	defense response to Gram-positive bacterium
0.46	GO:0050829	defense response to Gram-negative bacterium
0.46	GO:0050832	defense response to fungus

0.61	GO:0008233	peptidase activity
0.40	GO:0005515	protein binding
0.39	GO:0003723	RNA binding

0.66	GO:0005576	extracellular region
0.43	GO:0031982	vesicle

0.61

GO:0008233

sp|P81877|SSBP2_HUMAN
Single-stranded DNA-binding protein 2
Search

SSBP2

0.89	Single-stranded DNA-binding protein 2

0.45	GO:0045944	positive regulation of transcription by RNA polymerase II
0.45	GO:0006366	transcription by RNA polymerase II
0.37	GO:0021547	midbrain-hindbrain boundary initiation
0.37	GO:0021501	prechordal plate formation
0.37	GO:2000744	positive regulation of anterior head development
0.36	GO:0060323	head morphogenesis
0.36	GO:0002244	hematopoietic progenitor cell differentiation
0.36	GO:0008284	positive regulation of cell proliferation
0.35	GO:0006461	protein complex assembly

0.69	GO:0003697	single-stranded DNA binding
0.47	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.47	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.33	GO:0005515	protein binding

0.40	GO:0005634	nucleus
0.34	GO:0043234	protein complex
0.33	GO:0005737	cytoplasm

sp|P82094|TMF1_HUMAN
TATA element modulatory factor
Search

TMF1

0.93	TATA element modulatory factor

0.87	GO:2000845	positive regulation of testosterone secretion
0.87	GO:0032275	luteinizing hormone secretion
0.86	GO:0033327	Leydig cell differentiation
0.86	GO:0001675	acrosome assembly
0.85	GO:0007289	spermatid nucleus differentiation
0.84	GO:0030317	flagellated sperm motility
0.80	GO:0001819	positive regulation of cytokine production
0.78	GO:0061136	regulation of proteasomal protein catabolic process
0.77	GO:0043066	negative regulation of apoptotic process
0.77	GO:0042742	defense response to bacterium

0.40	GO:0008641	ubiquitin-like modifier activating enzyme activity
0.40	GO:0005515	protein binding
0.39	GO:0016881	acid-amino acid ligase activity
0.39	GO:0003712	transcription cofactor activity
0.36	GO:0003677	DNA binding
0.34	GO:0030554	adenyl nucleotide binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.70	GO:0005794	Golgi apparatus
0.69	GO:0005783	endoplasmic reticulum
0.40	GO:0098588	bounding membrane of organelle
0.40	GO:0031984	organelle subcompartment
0.38	GO:0005634	nucleus
0.37	GO:0005829	cytosol
0.36	GO:0005856	cytoskeleton

0.39

EC:6.3.2

GO:0016881

sp|P82251|BAT1_HUMAN
b(0,+)-type amino acid transporter 1
Search

SLC7A9

0.89	Solute carrier family 7 (Cationic amino acid transporter, y+ system), member 9

0.74	GO:0015811	L-cystine transport
0.64	GO:0015804	neutral amino acid transport
0.55	GO:0055085	transmembrane transport

0.74	GO:0015184	L-cystine transmembrane transporter activity
0.65	GO:0015175	neutral amino acid transmembrane transporter activity
0.48	GO:0015297	antiporter activity

0.70	GO:0031526	brush border membrane
0.66	GO:0016324	apical plasma membrane
0.46	GO:0005887	integral component of plasma membrane
0.37	GO:0005829	cytosol
0.35	GO:0043231	intracellular membrane-bounded organelle

sp|P82279|CRUM1_HUMAN
Protein crumbs homolog 1
Search

CRB1

0.76	Crumbs 1, cell polarity complex component

0.46	GO:0042462	eye photoreceptor cell development
0.46	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity
0.45	GO:0007009	plasma membrane organization
0.34	GO:0055111	ingression involved in gastrulation with mouth forming second
0.34	GO:0014028	notochord formation
0.34	GO:0006611	protein export from nucleus
0.34	GO:0035090	maintenance of apical/basal cell polarity
0.34	GO:0010718	positive regulation of epithelial to mesenchymal transition
0.34	GO:0010470	regulation of gastrulation
0.34	GO:0030513	positive regulation of BMP signaling pathway

0.70	GO:0005509	calcium ion binding
0.34	GO:0019828	aspartic-type endopeptidase inhibitor activity
0.34	GO:0003735	structural constituent of ribosome
0.33	GO:0005515	protein binding

0.46	GO:0005902	microvillus
0.46	GO:0005913	cell-cell adherens junction
0.42	GO:0043234	protein complex
0.38	GO:0005886	plasma membrane
0.35	GO:0045177	apical part of cell
0.34	GO:0001917	photoreceptor inner segment
0.34	GO:0005840	ribosome
0.33	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

sp|P82650|RT22_HUMAN
28S ribosomal protein S22, mitochondrial
Search

MRPS22

0.96	Mitochondrial ribosomal protein S22

0.38	GO:0032543	mitochondrial translation
0.36	GO:0006415	translational termination
0.35	GO:0006414	translational elongation

0.50

GO:0003735

structural constituent of ribosome

0.61	GO:0005763	mitochondrial small ribosomal subunit
0.35	GO:0031966	mitochondrial membrane
0.35	GO:0019866	organelle inner membrane

sp|P82663|RT25_HUMAN
28S ribosomal protein S25, mitochondrial
Search

MRPS25

0.97	Mitochondrial ribosomal protein S25

0.40	GO:0032543	mitochondrial translation
0.35	GO:0006415	translational termination
0.34	GO:0006414	translational elongation

0.43	GO:0003735	structural constituent of ribosome
0.34	GO:0046872	metal ion binding
0.33	GO:0016787	hydrolase activity
0.33	GO:0005515	protein binding
0.32	GO:0003676	nucleic acid binding

0.55	GO:0005840	ribosome
0.48	GO:0005739	mitochondrion
0.37	GO:0031974	membrane-enclosed lumen
0.36	GO:0044446	intracellular organelle part
0.35	GO:0031090	organelle membrane
0.34	GO:0031975	envelope
0.30	GO:0031224	intrinsic component of membrane

0.33

GO:0016787

sp|P82664|RT10_HUMAN
28S ribosomal protein S10, mitochondrial
Search

MRPS10

0.95	Mitochondrial ribosomal protein S10

0.51	GO:0043043	peptide biosynthetic process
0.48	GO:0044267	cellular protein metabolic process
0.47	GO:0010467	gene expression
0.46	GO:0009059	macromolecule biosynthetic process
0.34	GO:0043624	cellular protein complex disassembly

0.54	GO:0003735	structural constituent of ribosome
0.33	GO:0005509	calcium ion binding
0.32	GO:0003723	RNA binding
0.32	GO:0016787	hydrolase activity

0.60	GO:0005840	ribosome
0.53	GO:0005759	mitochondrial matrix
0.34	GO:0031966	mitochondrial membrane
0.34	GO:0019866	organelle inner membrane
0.32	GO:0005730	nucleolus

0.32

GO:0016787

sp|P82673|RT35_HUMAN
28S ribosomal protein S35, mitochondrial
Search

MRPS35

0.93	Mitochondrial ribosomal protein S35

0.39	GO:0032543	mitochondrial translation
0.38	GO:0042769	DNA damage response, detection of DNA damage
0.36	GO:0006415	translational termination
0.35	GO:0006414	translational elongation

0.44	GO:0003735	structural constituent of ribosome
0.35	GO:0003723	RNA binding

0.61	GO:0005840	ribosome
0.49	GO:0005759	mitochondrial matrix
0.36	GO:0031966	mitochondrial membrane
0.36	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P82675|RT05_HUMAN
28S ribosomal protein S5, mitochondrial
Search

MRPS5

0.96	Mitochondrial ribosomal protein S5

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.35	GO:0043624	cellular protein complex disassembly
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.33	GO:0010468	regulation of gene expression
0.33	GO:0007018	microtubule-based movement

0.64	GO:0003735	structural constituent of ribosome
0.58	GO:0003723	RNA binding
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0003777	microtubule motor activity
0.33	GO:0008017	microtubule binding
0.32	GO:0030554	adenyl nucleotide binding

0.61	GO:0005840	ribosome
0.53	GO:0005759	mitochondrial matrix
0.45	GO:0044445	cytosolic part
0.34	GO:0031966	mitochondrial membrane
0.34	GO:0019866	organelle inner membrane
0.33	GO:0005874	microtubule
0.30	GO:0031224	intrinsic component of membrane

sp|P82909|RT36_HUMAN
28S ribosomal protein S36, mitochondrial
Search

MRPS36

0.97	Mitochondrial ribosomal protein S36

0.40	GO:0051382	kinetochore assembly
0.40	GO:0070126	mitochondrial translational termination
0.39	GO:0070125	mitochondrial translational elongation

0.36

GO:0003735

structural constituent of ribosome

0.62	GO:0005763	mitochondrial small ribosomal subunit
0.58	GO:0009353	mitochondrial oxoglutarate dehydrogenase complex
0.39	GO:0000776	kinetochore
0.37	GO:0031966	mitochondrial membrane
0.37	GO:0019866	organelle inner membrane
0.36	GO:0005634	nucleus

sp|P82912|RT11_HUMAN
28S ribosomal protein S11, mitochondrial
Search

MRPS11

0.96	Mitochondrial ribosomal protein S11

0.60	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.50	GO:0000028	ribosomal small subunit assembly
0.44	GO:0016072	rRNA metabolic process

0.64	GO:0003735	structural constituent of ribosome
0.53	GO:0019843	rRNA binding
0.49	GO:0048027	mRNA 5'-UTR binding

0.62

GO:0005763

mitochondrial small ribosomal subunit

sp|P82914|RT15_HUMAN
28S ribosomal protein S15, mitochondrial
Search

MRPS15

0.92	Mitochondrial ribosomal protein S15

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.37	GO:0043624	cellular protein complex disassembly

0.64	GO:0003735	structural constituent of ribosome
0.36	GO:0003723	RNA binding

0.64	GO:0005763	mitochondrial small ribosomal subunit
0.57	GO:0005730	nucleolus
0.37	GO:0031966	mitochondrial membrane
0.37	GO:0019866	organelle inner membrane

sp|P82921|RT21_HUMAN
28S ribosomal protein S21, mitochondrial
Search

MRPS21

0.97	Mitochondrial ribosomal protein S21

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.34	GO:0043624	cellular protein complex disassembly
0.34	GO:0032922	circadian regulation of gene expression
0.33	GO:0016071	mRNA metabolic process

0.64	GO:0003735	structural constituent of ribosome
0.34	GO:0003723	RNA binding
0.34	GO:0000976	transcription regulatory region sequence-specific DNA binding
0.32	GO:0016787	hydrolase activity

0.61	GO:0005840	ribosome
0.43	GO:0044446	intracellular organelle part
0.43	GO:0031090	organelle membrane
0.43	GO:0005739	mitochondrion
0.42	GO:0031975	envelope
0.37	GO:0031974	membrane-enclosed lumen
0.34	GO:0120114	Sm-like protein family complex
0.33	GO:0019013	viral nucleocapsid
0.33	GO:0005634	nucleus

0.32

GO:0016787

sp|P82930|RT34_HUMAN
28S ribosomal protein S34, mitochondrial
Search

MRPS34

0.97	Mitochondrial ribosomal protein S34

0.59	GO:0032543	mitochondrial translation
0.36	GO:0006415	translational termination
0.35	GO:0006414	translational elongation

0.64

GO:0003735

structural constituent of ribosome

0.61	GO:0005739	mitochondrion
0.55	GO:0005840	ribosome
0.38	GO:0070013	intracellular organelle lumen
0.36	GO:0044446	intracellular organelle part
0.36	GO:0031090	organelle membrane
0.35	GO:0031975	envelope

sp|P82932|RT06_HUMAN
28S ribosomal protein S6, mitochondrial
Search

MRPS6

0.97	Mitochondrial ribosomal protein S6

0.60	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.36	GO:0043624	cellular protein complex disassembly
0.33	GO:0055085	transmembrane transport

0.66	GO:0019843	rRNA binding
0.64	GO:0003735	structural constituent of ribosome
0.34	GO:0005515	protein binding
0.33	GO:0022857	transmembrane transporter activity

0.63	GO:0005763	mitochondrial small ribosomal subunit
0.36	GO:0031966	mitochondrial membrane
0.36	GO:0019866	organelle inner membrane
0.30	GO:0031224	intrinsic component of membrane

sp|P82933|RT09_HUMAN
28S ribosomal protein S9, mitochondrial
Search

MRPS9

0.93	Mitochondrial ribosomal protein S9

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.45	GO:0042274	ribosomal small subunit biogenesis
0.43	GO:0016072	rRNA metabolic process
0.36	GO:0042769	DNA damage response, detection of DNA damage
0.35	GO:0043624	cellular protein complex disassembly
0.32	GO:0043039	tRNA aminoacylation

0.64	GO:0003735	structural constituent of ribosome
0.40	GO:0003723	RNA binding
0.34	GO:0005515	protein binding
0.32	GO:0016875	ligase activity, forming carbon-oxygen bonds
0.32	GO:0140101	catalytic activity, acting on a tRNA
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.61	GO:0005840	ribosome
0.52	GO:0005730	nucleolus
0.46	GO:0005739	mitochondrion
0.34	GO:0019866	organelle inner membrane

0.32

EC:6.1

GO:0016875

sp|P82970|HMGN5_HUMAN
High mobility group nucleosome-binding domain-containing protein 5
Search

HMGN5

0.92	High mobility group nucleosome-binding domain-containing protein 5

0.56	GO:0071157	negative regulation of cell cycle arrest
0.52	GO:0008284	positive regulation of cell proliferation
0.52	GO:0043066	negative regulation of apoptotic process
0.49	GO:0010628	positive regulation of gene expression
0.44	GO:0006357	regulation of transcription by RNA polymerase II
0.40	GO:0006325	chromatin organization
0.38	GO:0006749	glutathione metabolic process
0.36	GO:0043412	macromolecule modification
0.36	GO:0048597	post-embryonic camera-type eye morphogenesis
0.36	GO:0000720	pyrimidine dimer repair by nucleotide-excision repair

0.84	GO:0031492	nucleosomal DNA binding
0.35	GO:0003723	RNA binding
0.34	GO:0008270	zinc ion binding
0.34	GO:0008083	growth factor activity
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding
0.33	GO:0004672	protein kinase activity
0.33	GO:0030554	adenyl nucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0043021	ribonucleoprotein complex binding

0.70	GO:0000785	chromatin
0.60	GO:0005634	nucleus
0.37	GO:0031974	membrane-enclosed lumen
0.33	GO:0030687	preribosome, large subunit precursor
0.33	GO:0005576	extracellular region
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|P82979|SARNP_HUMAN
SAP domain-containing ribonucleoprotein
Search

SARNP

0.93	Cytokine induced protein 29 kDa

0.58	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.55	GO:0051028	mRNA transport
0.55	GO:0006405	RNA export from nucleus
0.43	GO:0010467	gene expression
0.39	GO:0006417	regulation of translation
0.38	GO:0000122	negative regulation of transcription by RNA polymerase II
0.37	GO:0097659	nucleic acid-templated transcription
0.35	GO:0034645	cellular macromolecule biosynthetic process
0.35	GO:0016071	mRNA metabolic process
0.33	GO:0019082	viral protein processing

0.40	GO:0050733	RS domain binding
0.39	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.38	GO:0008022	protein C-terminus binding
0.38	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.37	GO:0003723	RNA binding
0.33	GO:0004197	cysteine-type endopeptidase activity
0.33	GO:0070008	serine-type exopeptidase activity
0.33	GO:0003968	RNA-directed 5'-3' RNA polymerase activity
0.33	GO:0004252	serine-type endopeptidase activity
0.32	GO:0017111	nucleoside-triphosphatase activity

0.64	GO:0019013	viral nucleocapsid
0.60	GO:0000346	transcription export complex
0.60	GO:0030529	intracellular ribonucleoprotein complex
0.58	GO:0016607	nuclear speck
0.46	GO:0043232	intracellular non-membrane-bounded organelle
0.44	GO:0044444	cytoplasmic part
0.30	GO:0016020	membrane

0.33

EC:3.4.22

GO:0004197

sp|P82980|RET5_HUMAN
Retinol-binding protein 5
Search

RBP5

0.97	Cellular retinol-binding protein III

0.69	GO:0006776	vitamin A metabolic process
0.68	GO:0002138	retinoic acid biosynthetic process
0.49	GO:0033189	response to vitamin A
0.48	GO:0030852	regulation of granulocyte differentiation
0.47	GO:0042572	retinol metabolic process
0.36	GO:0055088	lipid homeostasis
0.34	GO:0006958	complement activation, classical pathway
0.33	GO:0009435	NAD biosynthetic process
0.33	GO:0006508	proteolysis

0.72	GO:0008289	lipid binding
0.53	GO:0019842	vitamin binding
0.40	GO:0043178	alcohol binding
0.34	GO:0004252	serine-type endopeptidase activity
0.34	GO:0016779	nucleotidyltransferase activity
0.33	GO:0005515	protein binding
0.33	GO:0005509	calcium ion binding
0.31	GO:0032559	adenyl ribonucleotide binding
0.31	GO:0008144	drug binding
0.31	GO:0035639	purine ribonucleoside triphosphate binding

0.54	GO:0005829	cytosol
0.46	GO:0005811	lipid droplet
0.43	GO:0005654	nucleoplasm
0.36	GO:0044297	cell body
0.34	GO:0070062	extracellular exosome

0.34

GO:0004252

sp|P82987|ATL3_HUMAN
ADAMTS-like protein 3
Search

ADAMTSL1

0.56	ADAMTS like 3

0.60

GO:0006508

proteolysis

0.61

GO:0008233

peptidase activity

0.40

GO:0043231

intracellular membrane-bounded organelle

0.61

GO:0008233

sp|P83105|HTRA4_HUMAN
Serine protease HTRA4
Search

HTRA4

0.42	Serine protease

0.69	GO:0001558	regulation of cell growth
0.61	GO:0006508	proteolysis
0.52	GO:0060718	chorionic trophoblast cell differentiation
0.52	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.51	GO:0030514	negative regulation of BMP signaling pathway
0.48	GO:0001890	placenta development
0.38	GO:0097187	dentinogenesis
0.38	GO:0050687	negative regulation of defense response to virus
0.37	GO:0050679	positive regulation of epithelial cell proliferation
0.35	GO:0022617	extracellular matrix disassembly

0.72	GO:0005520	insulin-like growth factor binding
0.69	GO:0004252	serine-type endopeptidase activity
0.45	GO:0042802	identical protein binding
0.33	GO:0004222	metalloendopeptidase activity
0.33	GO:0016875	ligase activity, forming carbon-oxygen bonds
0.33	GO:0140101	catalytic activity, acting on a tRNA
0.32	GO:0046872	metal ion binding
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.59	GO:0005576	extracellular region
0.39	GO:0005886	plasma membrane
0.37	GO:0005829	cytosol
0.35	GO:0031982	vesicle
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0004252

sp|P83110|HTRA3_HUMAN
Serine protease HTRA3
Search

HTRA3

0.95	HtrA serine peptidase 3

0.78	GO:0001558	regulation of cell growth
0.65	GO:0030514	negative regulation of BMP signaling pathway
0.65	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.61	GO:0006508	proteolysis
0.40	GO:0040036	regulation of fibroblast growth factor receptor signaling pathway
0.37	GO:0060718	chorionic trophoblast cell differentiation
0.36	GO:0001890	placenta development

0.82	GO:0005520	insulin-like growth factor binding
0.69	GO:0004252	serine-type endopeptidase activity
0.35	GO:0042802	identical protein binding

0.65	GO:0005576	extracellular region
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.69

GO:0004252

sp|P83111|LACTB_HUMAN
Serine beta-lactamase-like protein LACTB, mitochondrial
Search

LACTB

0.96	Lactamase beta

0.74	GO:0019216	regulation of lipid metabolic process
0.58	GO:0006508	proteolysis
0.40	GO:0006629	lipid metabolic process

0.58	GO:0008233	peptidase activity
0.45	GO:0042802	identical protein binding

0.65	GO:0005829	cytosol
0.57	GO:0005739	mitochondrion
0.30	GO:0031224	intrinsic component of membrane

0.58

GO:0008233

sp|P83369|LSM11_HUMAN
U7 snRNA-associated Sm-like protein LSm11
Search

LSM11

0.94	LSM11, U7 small nuclear RNA associated

0.72	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage
0.67	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle
0.41	GO:0006369	termination of RNA polymerase II transcription
0.34	GO:0006400	tRNA modification

0.72	GO:0071209	U7 snRNA binding
0.39	GO:0005515	protein binding
0.36	GO:0008193	tRNA guanylyltransferase activity
0.34	GO:0000287	magnesium ion binding

0.72	GO:0005683	U7 snRNP
0.71	GO:0071204	histone pre-mRNA 3'end processing complex
0.67	GO:0005697	telomerase holoenzyme complex
0.61	GO:0016604	nuclear body
0.30	GO:0031224	intrinsic component of membrane

0.36

EC:2.7.7

GO:0008193

sp|P83436|COG7_HUMAN
Conserved oligomeric Golgi complex subunit 7
Search

COG7

0.93	Component of oligomeric golgi complex 7

0.68	GO:0006886	intracellular protein transport
0.58	GO:0034067	protein localization to Golgi apparatus
0.57	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.55	GO:0050821	protein stabilization
0.52	GO:0006486	protein glycosylation
0.47	GO:0007030	Golgi organization
0.36	GO:0006891	intra-Golgi vesicle-mediated transport
0.35	GO:0006888	ER to Golgi vesicle-mediated transport

0.34

GO:0005515

protein binding

0.79	GO:0017119	Golgi transport complex
0.52	GO:0005730	nucleolus
0.38	GO:0000139	Golgi membrane
0.35	GO:0005802	trans-Golgi network
0.34	GO:0030131	clathrin adaptor complex
0.30	GO:0031224	intrinsic component of membrane

sp|P83731|RL24_HUMAN
60S ribosomal protein L24
Search

RPL24

0.70	Ribosomal protein L24

0.50	GO:1902626	assembly of large subunit precursor of preribosome
0.49	GO:0000027	ribosomal large subunit assembly
0.47	GO:0002181	cytoplasmic translation
0.46	GO:0021554	optic nerve development
0.45	GO:0010458	exit from mitosis
0.45	GO:0031290	retinal ganglion cell axon guidance
0.44	GO:0060041	retina development in camera-type eye
0.43	GO:0007093	mitotic cell cycle checkpoint
0.36	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.35	GO:0043009	chordate embryonic development

0.49	GO:0045296	cadherin binding
0.42	GO:0003735	structural constituent of ribosome
0.40	GO:0003723	RNA binding
0.32	GO:0016787	hydrolase activity

0.59	GO:0005840	ribosome
0.48	GO:0044445	cytosolic part
0.48	GO:0005844	polysome
0.45	GO:0005783	endoplasmic reticulum
0.42	GO:0044446	intracellular organelle part
0.37	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0016787

sp|P83859|OX26_HUMAN
Orexigenic neuropeptide QRFP
Search

QRFP

0.97	Pyroglutamylated RFamide prepropeptide

0.68	GO:0007625	grooming behavior
0.68	GO:0045777	positive regulation of blood pressure
0.67	GO:0060259	regulation of feeding behavior
0.65	GO:0007218	neuropeptide signaling pathway
0.63	GO:0007626	locomotory behavior
0.61	GO:0010469	regulation of receptor activity

0.88	GO:0031854	orexigenic neuropeptide QRFP receptor binding
0.68	GO:0005184	neuropeptide hormone activity

sp|P83876|TXN4A_HUMAN
Thioredoxin-like protein 4A
Search

TXNL4A

0.82	Thioredoxin like 4A

0.75	GO:0000398	mRNA splicing, via spliceosome
0.42	GO:0022618	ribonucleoprotein complex assembly
0.34	GO:0051301	cell division
0.34	GO:0007049	cell cycle
0.34	GO:0009264	deoxyribonucleotide catabolic process

0.34	GO:0004139	deoxyribose-phosphate aldolase activity
0.33	GO:0005515	protein binding

0.76	GO:0005681	spliceosomal complex
0.49	GO:0031965	nuclear membrane
0.45	GO:0005682	U5 snRNP
0.45	GO:0005829	cytosol
0.44	GO:0046540	U4/U6 x U5 tri-snRNP complex
0.33	GO:0005654	nucleoplasm

0.34	EC:4.1.2.4	GO:0004139
0.34	KEGG:R01066	GO:0004139

sp|P83881|RL36A_HUMAN
60S ribosomal protein L36a
Search

RPL36A

0.91	Ribosomal protein L36a like

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.42	GO:0043009	chordate embryonic development
0.40	GO:0051726	regulation of cell cycle
0.34	GO:0032526	response to retinoic acid
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.33	GO:0019083	viral transcription

0.64	GO:0003735	structural constituent of ribosome
0.34	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.34	GO:0005515	protein binding
0.33	GO:0003723	RNA binding
0.33	GO:0046872	metal ion binding

0.61	GO:0005840	ribosome
0.48	GO:0005829	cytosol
0.42	GO:0005783	endoplasmic reticulum
0.41	GO:0044446	intracellular organelle part
0.38	GO:0005886	plasma membrane
0.37	GO:0005634	nucleus
0.34	GO:0005844	polysome
0.34	GO:0098562	cytoplasmic side of membrane
0.33	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.33	GO:0098588	bounding membrane of organelle

0.34

GO:0008138

sp|P83916|CBX1_HUMAN
Chromobox protein homolog 1
Search

CBX1

0.97	Chromobox protein like protein 1

0.45	GO:0045892	negative regulation of transcription, DNA-templated
0.35	GO:0043043	peptide biosynthetic process
0.34	GO:0044267	cellular protein metabolic process
0.34	GO:0010467	gene expression
0.34	GO:0009059	macromolecule biosynthetic process

0.54	GO:1990226	histone methyltransferase binding
0.46	GO:0042803	protein homodimerization activity
0.35	GO:0003735	structural constituent of ribosome
0.34	GO:0003682	chromatin binding
0.34	GO:0003779	actin binding

0.60	GO:0005634	nucleus
0.51	GO:0010369	chromocenter
0.50	GO:0005721	pericentric heterochromatin
0.49	GO:0000781	chromosome, telomeric region
0.48	GO:0005819	spindle
0.45	GO:0031974	membrane-enclosed lumen
0.35	GO:0005840	ribosome
0.30	GO:0031224	intrinsic component of membrane

sp|P84022|SMAD3_HUMAN
Mothers against decapentaplegic homolog 3
Search

SMAD3

0.65	Mothers against decapentaplegic homolog

0.83	GO:0007179	transforming growth factor beta receptor signaling pathway
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:0006355	regulation of transcription, DNA-templated
0.56	GO:0033689	negative regulation of osteoblast proliferation
0.56	GO:0048617	embryonic foregut morphogenesis
0.55	GO:0007183	SMAD protein complex assembly
0.55	GO:0048340	paraxial mesoderm morphogenesis
0.55	GO:0051481	negative regulation of cytosolic calcium ion concentration
0.55	GO:0002076	osteoblast development
0.55	GO:0038092	nodal signaling pathway

0.61	GO:0003700	DNA binding transcription factor activity
0.57	GO:0031962	mineralocorticoid receptor binding
0.56	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
0.55	GO:0035259	glucocorticoid receptor binding
0.55	GO:0017151	DEAD/H-box RNA helicase binding
0.55	GO:0070410	co-SMAD binding
0.55	GO:0070878	primary miRNA binding
0.55	GO:0003677	DNA binding
0.54	GO:0070412	R-SMAD binding
0.54	GO:0043425	bHLH transcription factor binding

0.75	GO:0005667	transcription factor complex
0.61	GO:0005634	nucleus
0.55	GO:0071141	SMAD protein complex
0.50	GO:0043235	receptor complex
0.49	GO:0005737	cytoplasm
0.47	GO:0000785	chromatin
0.46	GO:0070013	intracellular organelle lumen
0.45	GO:0012505	endomembrane system
0.43	GO:0019866	organelle inner membrane
0.41	GO:0005886	plasma membrane

sp|P84074|HPCA_HUMAN
Neuron-specific calcium-binding protein hippocalcin
Search

HPCA

0.95	Neuron-specific calcium-binding protein hippocalcin

0.63	GO:1901385	regulation of voltage-gated calcium channel activity
0.62	GO:0071277	cellular response to calcium ion
0.59	GO:0048839	inner ear development
0.43	GO:1904010	response to Aroclor 1254
0.43	GO:1901986	response to ketamine
0.43	GO:1904009	cellular response to monosodium glutamate
0.42	GO:1902065	response to L-glutamate
0.42	GO:0031283	negative regulation of guanylate cyclase activity
0.42	GO:0031584	activation of phospholipase D activity
0.41	GO:0071257	cellular response to electrical stimulus

0.70	GO:0005509	calcium ion binding
0.55	GO:0042802	identical protein binding
0.54	GO:0003779	actin binding
0.39	GO:0019900	kinase binding

0.42	GO:0044327	dendritic spine head
0.41	GO:0032809	neuronal cell body membrane
0.41	GO:0032839	dendrite cytoplasm
0.41	GO:0032590	dendrite membrane
0.41	GO:0019898	extrinsic component of membrane
0.40	GO:0043204	perikaryon
0.39	GO:0030424	axon
0.39	GO:0005829	cytosol

sp|P84077|ARF1_HUMAN
ADP-ribosylation factor 1
Search

ARF1

0.70	ADP-ribosylation factor 1 like

0.54	GO:1990386	mitotic cleavage furrow ingression
0.50	GO:0098586	cellular response to virus
0.49	GO:0016192	vesicle-mediated transport
0.48	GO:0006878	cellular copper ion homeostasis
0.41	GO:0060292	long term synaptic depression
0.41	GO:0097061	dendritic spine organization
0.41	GO:0002090	regulation of receptor internalization
0.40	GO:1903337	positive regulation of vacuolar transport
0.40	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation
0.40	GO:1902822	regulation of late endosome to lysosome transport

0.66	GO:0005525	GTP binding
0.47	GO:0019904	protein domain specific binding
0.46	GO:0046982	protein heterodimerization activity
0.43	GO:0000287	magnesium ion binding
0.41	GO:1990583	phospholipase D activator activity
0.38	GO:0019003	GDP binding
0.34	GO:0003924	GTPase activity
0.34	GO:0005057	signal transducer activity, downstream of receptor
0.33	GO:0005102	receptor binding
0.33	GO:0003755	peptidyl-prolyl cis-trans isomerase activity

0.51	GO:0005794	Golgi apparatus
0.49	GO:0030017	sarcomere
0.48	GO:0031252	cell leading edge
0.44	GO:0005829	cytosol
0.41	GO:0048471	perinuclear region of cytoplasm
0.41	GO:0043234	protein complex
0.39	GO:0031982	vesicle
0.39	GO:0014069	postsynaptic density
0.38	GO:0043230	extracellular organelle
0.38	GO:0045211	postsynaptic membrane

0.33

GO:0003755

sp|P84085|ARF5_HUMAN
ADP-ribosylation factor 5
Search

0.92	ADP-ribosylation factor 5

0.59	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.55	GO:0031584	activation of phospholipase D activity
0.53	GO:0060996	dendritic spine development
0.53	GO:0045176	apical protein localization
0.52	GO:0061512	protein localization to cilium
0.52	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity
0.51	GO:0006471	protein ADP-ribosylation
0.51	GO:2000377	regulation of reactive oxygen species metabolic process
0.51	GO:0007612	learning
0.49	GO:0043066	negative regulation of apoptotic process

0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0005154	epidermal growth factor receptor binding
0.35	GO:0005085	guanyl-nucleotide exchange factor activity
0.34	GO:0003924	GTPase activity
0.34	GO:0017137	Rab GTPase binding

0.52	GO:0032587	ruffle membrane
0.52	GO:0043197	dendritic spine
0.48	GO:0005794	Golgi apparatus
0.45	GO:0005829	cytosol
0.38	GO:0070062	extracellular exosome
0.37	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0031012	extracellular matrix
0.34	GO:0070382	exocytic vesicle
0.30	GO:0016021	integral component of membrane

sp|P84090|ERH_HUMAN
Enhancer of rudimentary homolog
Search

ERH

0.85	Enhancer of rudimentary homolog

0.84	GO:0045747	positive regulation of Notch signaling pathway
0.69	GO:0006221	pyrimidine nucleotide biosynthetic process
0.66	GO:0007049	cell cycle
0.35	GO:0001649	osteoblast differentiation
0.33	GO:0006213	pyrimidine nucleoside metabolic process

0.51	GO:0008327	methyl-CpG binding
0.34	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.50	GO:0034709	methylosome
0.49	GO:0030496	midbody
0.30	GO:0016020	membrane

sp|P84095|RHOG_HUMAN
Rho-related GTP-binding protein RhoG
Search

RHOG

0.91	Ras homolog gene family, member Gc

0.77	GO:0007264	small GTPase mediated signal transduction
0.70	GO:1903078	positive regulation of protein localization to plasma membrane
0.70	GO:1900027	regulation of ruffle assembly
0.69	GO:0090630	activation of GTPase activity
0.67	GO:0060326	cell chemotaxis
0.61	GO:0030036	actin cytoskeleton organization
0.61	GO:0045893	positive regulation of transcription, DNA-templated
0.45	GO:0009617	response to bacterium
0.34	GO:0016192	vesicle-mediated transport

0.68	GO:0003924	GTPase activity
0.66	GO:0032550	purine ribonucleoside binding
0.66	GO:0019001	guanyl nucleotide binding
0.54	GO:0032555	purine ribonucleotide binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.45	GO:0005622	intracellular
0.42	GO:0005925	focal adhesion
0.42	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

sp|P84098|RL19_HUMAN
60S ribosomal protein L19
Search

RPL19

0.67	Ribosomal protein L19

0.60	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.38	GO:0030097	hemopoiesis
0.35	GO:0097421	liver regeneration
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.33	GO:0016072	rRNA metabolic process

0.63	GO:0003735	structural constituent of ribosome
0.40	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.79	GO:0022625	cytosolic large ribosomal subunit
0.48	GO:0042788	polysomal ribosome
0.36	GO:0005925	focal adhesion
0.33	GO:0019013	viral nucleocapsid
0.30	GO:0016020	membrane

sp|P84101|SERF2_HUMAN
Small EDRK-rich factor 2
Search

SERF2

0.96	small EDRK-rich factor 2

0.47	GO:0000413	protein peptidyl-prolyl isomerization
0.40	GO:0007399	nervous system development

0.48

GO:0003755

peptidyl-prolyl cis-trans isomerase activity

0.55	GO:0005829	cytosol
0.50	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.48

GO:0003755

sp|P84103|SRSF3_HUMAN
Serine/arginine-rich splicing factor 3
Search

SRSF3

0.95	Serine and arginine rich splicing factor 3

0.48	GO:1990830	cellular response to leukemia inhibitory factor
0.47	GO:0048024	regulation of mRNA splicing, via spliceosome
0.35	GO:0051028	mRNA transport
0.35	GO:0008380	RNA splicing
0.34	GO:0007050	cell cycle arrest
0.34	GO:0071901	negative regulation of protein serine/threonine kinase activity
0.34	GO:0006397	mRNA processing
0.32	GO:0008286	insulin receptor signaling pathway
0.32	GO:0006369	termination of RNA polymerase II transcription
0.32	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus

0.59	GO:0003723	RNA binding
0.50	GO:0043274	phospholipase binding
0.35	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0032561	guanyl ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.48	GO:0016607	nuclear speck
0.33	GO:0005576	extracellular region
0.32	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|P84157|MXRA7_HUMAN
Matrix-remodeling-associated protein 7
Search

MXRA7

0.92	Matrix-remodeling-associated protein 7

0.71	GO:0031012	extracellular matrix
0.30	GO:0044425	membrane part

sp|P84243|H33_HUMAN
Histone H3.3
Search

0.43	GO:0006334	nucleosome assembly
0.37	GO:0007140	male meiotic nuclear division
0.36	GO:0034724	DNA replication-independent nucleosome organization
0.36	GO:0030307	positive regulation of cell growth
0.30	GO:0060966	regulation of gene silencing by RNA
0.30	GO:0045892	negative regulation of transcription, DNA-templated
0.30	GO:0044237	cellular metabolic process
0.30	GO:0010608	posttranscriptional regulation of gene expression
0.30	GO:2000736	regulation of stem cell differentiation
0.30	GO:0042221	response to chemical

0.74	GO:0046982	protein heterodimerization activity
0.55	GO:0003677	DNA binding
0.45	GO:0031491	nucleosome binding
0.39	GO:0098770	FBXO family protein binding
0.35	GO:0001067	regulatory region nucleic acid binding

0.75	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.37	GO:0005700	polytene chromosome
0.35	GO:0000781	chromosome, telomeric region
0.34	GO:0043233	organelle lumen
0.33	GO:0043234	protein complex
0.30	GO:0005615	extracellular space
0.30	GO:0043230	extracellular organelle
0.30	GO:0031982	vesicle

sp|P84550|SKOR1_HUMAN
SKI family transcriptional corepressor 1
Search

SKOR1

0.86	SKI family transcriptional corepressor 1

0.84	GO:0090101	negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
0.83	GO:0090288	negative regulation of cellular response to growth factor stimulus
0.81	GO:0030510	regulation of BMP signaling pathway
0.72	GO:1903507	negative regulation of nucleic acid-templated transcription
0.65	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway
0.59	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
0.57	GO:0045596	negative regulation of cell differentiation
0.57	GO:0010629	negative regulation of gene expression
0.56	GO:0030182	neuron differentiation
0.55	GO:0048468	cell development

0.85	GO:0046332	SMAD binding
0.81	GO:0003714	transcription corepressor activity
0.42	GO:0042826	histone deacetylase binding
0.41	GO:0003682	chromatin binding
0.35	GO:0003677	DNA binding
0.34	GO:0004672	protein kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.63	GO:0043025	neuronal cell body
0.62	GO:0030425	dendrite
0.60	GO:0005667	transcription factor complex
0.55	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

sp|P85037|FOXK1_HUMAN
Forkhead box protein K1
Search

FOXK1

0.97	Forkhead box protein K1

0.56	GO:0006355	regulation of transcription, DNA-templated
0.52	GO:1903508	positive regulation of nucleic acid-templated transcription
0.51	GO:0010628	positive regulation of gene expression
0.50	GO:1903507	negative regulation of nucleic acid-templated transcription
0.50	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
0.49	GO:0010629	negative regulation of gene expression
0.47	GO:0030154	cell differentiation
0.47	GO:0009653	anatomical structure morphogenesis
0.38	GO:0007517	muscle organ development
0.37	GO:0006351	transcription, DNA-templated

0.63	GO:0043565	sequence-specific DNA binding
0.60	GO:0003700	DNA binding transcription factor activity
0.54	GO:0001012	RNA polymerase II regulatory region DNA binding
0.51	GO:0003690	double-stranded DNA binding
0.36	GO:0000287	magnesium ion binding
0.35	GO:0005515	protein binding
0.33	GO:0002151	G-quadruplex RNA binding

0.60	GO:0005634	nucleus
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0044446	intracellular organelle part
0.33	GO:0005737	cytoplasm
0.33	GO:0034708	methyltransferase complex
0.33	GO:0033202	DNA helicase complex
0.32	GO:0005694	chromosome
0.32	GO:1904949	ATPase complex
0.30	GO:0031224	intrinsic component of membrane

sp|P85298|RHG08_HUMAN
Rho GTPase-activating protein 8
Search

ARHGAP8

0.83	Rho GTPase-activating protein 8

0.60	GO:0007165	signal transduction
0.47	GO:0043087	regulation of GTPase activity
0.40	GO:0051345	positive regulation of hydrolase activity
0.38	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.37	GO:0051056	regulation of small GTPase mediated signal transduction
0.35	GO:0030335	positive regulation of cell migration
0.35	GO:2001136	negative regulation of endocytic recycling
0.35	GO:0030036	actin cytoskeleton organization
0.35	GO:0098706	ferric iron import across plasma membrane
0.34	GO:0033572	transferrin transport

0.41	GO:0030695	GTPase regulator activity
0.40	GO:0008047	enzyme activator activity
0.35	GO:0005515	protein binding

0.37	GO:0005737	cytoplasm
0.33	GO:0097708	intracellular vesicle
0.33	GO:0098805	whole membrane
0.33	GO:0098588	bounding membrane of organelle
0.33	GO:0012505	endomembrane system
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016021	integral component of membrane

sp|P85299|PRR5_HUMAN
Proline-rich protein 5
Search

PRR5

0.96	Proline-rich protein 5

0.72	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling
0.67	GO:0038203	TORC2 signaling
0.65	GO:0001934	positive regulation of protein phosphorylation
0.43	GO:0050790	regulation of catalytic activity
0.42	GO:0007049	cell cycle
0.41	GO:0044093	positive regulation of molecular function
0.39	GO:0030335	positive regulation of cell migration
0.38	GO:0030036	actin cytoskeleton organization

0.38

GO:0005096

GTPase activator activity

0.75	GO:0031932	TORC2 complex
0.38	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|P86397|HTD2_HUMAN
Hydroxyacyl-thioester dehydratase type 2, mitochondrial
Search

HTD2

0.33	MaoC domain-containing protein dehydratase

0.49	GO:0006631	fatty acid metabolic process
0.47	GO:0072330	monocarboxylic acid biosynthetic process
0.45	GO:0008610	lipid biosynthetic process
0.44	GO:0046949	fatty-acyl-CoA biosynthetic process
0.44	GO:0090501	RNA phosphodiester bond hydrolysis
0.43	GO:0008033	tRNA processing
0.40	GO:0055114	oxidation-reduction process
0.40	GO:0006954	inflammatory response
0.37	GO:0006468	protein phosphorylation

0.49	GO:0004312	fatty acid synthase activity
0.45	GO:0018812	3-hydroxyacyl-CoA dehydratase activity
0.44	GO:0004540	ribonuclease activity
0.39	GO:0035091	phosphatidylinositol binding
0.39	GO:0003779	actin binding
0.37	GO:0008959	phosphate acetyltransferase activity
0.37	GO:0004672	protein kinase activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.62	GO:0005730	nucleolus
0.53	GO:0005739	mitochondrion
0.52	GO:0005835	fatty acid synthase complex
0.39	GO:0005815	microtubule organizing center
0.35	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.49

EC:2.3.1.85

GO:0004312

sp|P86434|AAS1_HUMAN
Putative uncharacterized protein ADORA2A-AS1
Search

sp|P86452|ZBED6_HUMAN
Zinc finger BED domain-containing protein 6
Search

0.10	Zinc finger BED domain-containing protein 6

0.61	GO:0006357	regulation of transcription by RNA polymerase II
0.30	GO:0045892	negative regulation of transcription, DNA-templated
0.30	GO:0090304	nucleic acid metabolic process
0.30	GO:0018130	heterocycle biosynthetic process
0.30	GO:1901362	organic cyclic compound biosynthetic process
0.30	GO:0019438	aromatic compound biosynthetic process
0.30	GO:0010467	gene expression
0.30	GO:0044260	cellular macromolecule metabolic process
0.30	GO:0009059	macromolecule biosynthetic process
0.30	GO:0044271	cellular nitrogen compound biosynthetic process

0.68	GO:0046983	protein dimerization activity
0.67	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.54	GO:0003700	DNA binding transcription factor activity
0.30	GO:0043167	ion binding

0.54	GO:0005634	nucleus
0.30	GO:0031974	membrane-enclosed lumen
0.30	GO:0043232	intracellular non-membrane-bounded organelle
0.30	GO:0044422	organelle part

sp|P86478|PR20E_HUMAN
Proline-rich protein 20E
Search

sp|P86479|PR20C_HUMAN
Proline-rich protein 20C
Search

0.53	Proline-rich protein 20E

0.63

GO:0005515

protein binding

sp|P86480|PR20D_HUMAN
Proline-rich protein 20D
Search

0.53	Proline-rich protein 20E

0.63

GO:0005515

protein binding

sp|P86481|PR20B_HUMAN
Proline-rich protein 20B
Search

0.53	Proline-rich protein 20E

0.63

GO:0005515

protein binding

sp|P86496|PR20A_HUMAN
Proline-rich protein 20A
Search

0.53	Proline-rich protein 20E

0.63

GO:0005515

protein binding

sp|P86790|CCZ1B_HUMAN
Vacuolar fusion protein CCZ1 homolog B
Search

CCZ1

0.90	CCZ1 homolog B, vacuolar protein-trafficking and biogenesis-associated

0.61	GO:0016192	vesicle-mediated transport
0.52	GO:0065009	regulation of molecular function
0.38	GO:0023052	signaling

0.58	GO:0005085	guanyl-nucleotide exchange factor activity
0.45	GO:0005509	calcium ion binding

0.72	GO:0005765	lysosomal membrane
0.68	GO:0035658	Mon1-Ccz1 complex
0.58	GO:0016235	aggresome
0.49	GO:0005829	cytosol

sp|P86791|CCZ1_HUMAN
Vacuolar fusion protein CCZ1 homolog
Search

CCZ1

0.90	CCZ1 homolog B, vacuolar protein-trafficking and biogenesis-associated

0.61	GO:0016192	vesicle-mediated transport
0.52	GO:0065009	regulation of molecular function
0.38	GO:0023052	signaling

0.58	GO:0005085	guanyl-nucleotide exchange factor activity
0.45	GO:0005509	calcium ion binding

0.72	GO:0005765	lysosomal membrane
0.68	GO:0035658	Mon1-Ccz1 complex
0.58	GO:0016235	aggresome
0.49	GO:0005829	cytosol

sp|P98066|TSG6_HUMAN
Tumor necrosis factor-inducible gene 6 protein
Search

TNFAIP6

0.97	Tumor necrosis factor alpha-induced protein 6

0.72	GO:0007155	cell adhesion
0.61	GO:0050728	negative regulation of inflammatory response
0.42	GO:0030728	ovulation
0.41	GO:0030335	positive regulation of cell migration
0.36	GO:0007267	cell-cell signaling
0.36	GO:0043312	neutrophil degranulation
0.36	GO:0006952	defense response
0.35	GO:0016525	negative regulation of angiogenesis
0.35	GO:0009617	response to bacterium
0.34	GO:0006898	receptor-mediated endocytosis

0.84	GO:0005540	hyaluronic acid binding
0.38	GO:0005509	calcium ion binding
0.36	GO:0005041	low-density lipoprotein receptor activity
0.36	GO:0030169	low-density lipoprotein particle binding
0.35	GO:0005044	scavenger receptor activity
0.33	GO:0005515	protein binding
0.33	GO:0003735	structural constituent of ribosome
0.32	GO:0004930	G-protein coupled receptor activity
0.32	GO:0004222	metalloendopeptidase activity
0.32	GO:0008270	zinc ion binding

0.39	GO:0005615	extracellular space
0.36	GO:1904724	tertiary granule lumen
0.36	GO:1904813	ficolin-1-rich granule lumen
0.34	GO:0005887	integral component of plasma membrane
0.33	GO:0005840	ribosome

0.32

GO:0004222

sp|P98073|ENTK_HUMAN
Enteropeptidase
Search

TMPRSS15

0.89	Enteropeptidase

0.66	GO:0006898	receptor-mediated endocytosis
0.60	GO:0006508	proteolysis
0.39	GO:0044256	protein digestion
0.36	GO:0051604	protein maturation
0.34	GO:0016310	phosphorylation
0.34	GO:0007340	acrosome reaction
0.32	GO:0007596	blood coagulation

0.74	GO:0005044	scavenger receptor activity
0.68	GO:0004252	serine-type endopeptidase activity
0.35	GO:0005515	protein binding
0.35	GO:0016301	kinase activity
0.32	GO:0005509	calcium ion binding

0.38	GO:0005903	brush border
0.37	GO:0001669	acrosomal vesicle
0.33	GO:0044437	vacuolar part
0.33	GO:0044433	cytoplasmic vesicle part
0.33	GO:0005576	extracellular region
0.30	GO:0016020	membrane

0.68

GO:0004252

sp|P98077|SHC2_HUMAN
SHC-transforming protein 2
Search

0.94	RNA polymerase mitochondrial

0.79	GO:0000187	activation of MAPK activity
0.62	GO:0035556	intracellular signal transduction
0.58	GO:0001525	angiogenesis
0.51	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.47	GO:0070374	positive regulation of ERK1 and ERK2 cascade
0.46	GO:0071363	cellular response to growth factor stimulus
0.45	GO:0043066	negative regulation of apoptotic process
0.45	GO:0042742	defense response to bacterium
0.44	GO:0042127	regulation of cell proliferation
0.44	GO:0007507	heart development

0.85	GO:0030971	receptor tyrosine kinase binding
0.50	GO:0005168	neurotrophin TRKA receptor binding
0.48	GO:0005159	insulin-like growth factor receptor binding
0.48	GO:0005158	insulin receptor binding
0.48	GO:0048408	epidermal growth factor binding
0.48	GO:0001784	phosphotyrosine residue binding
0.48	GO:0046875	ephrin receptor binding
0.37	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.35	GO:0005154	epidermal growth factor receptor binding
0.35	GO:0019904	protein domain specific binding

0.45	GO:0005622	intracellular
0.42	GO:0005886	plasma membrane
0.34	GO:0031974	membrane-enclosed lumen
0.34	GO:0009295	nucleoid
0.33	GO:0061695	transferase complex, transferring phosphorus-containing groups
0.33	GO:0044422	organelle part
0.33	GO:0043227	membrane-bounded organelle
0.33	GO:0098796	membrane protein complex
0.32	GO:0043228	non-membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

0.33

GO:0003899

sp|P98082|DAB2_HUMAN
Disabled homolog 2
Search

DAB2

0.91	Disabled like protein 2

0.87	GO:0035026	leading edge cell differentiation
0.86	GO:2000370	positive regulation of clathrin-dependent endocytosis
0.86	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway
0.86	GO:2000643	positive regulation of early endosome to late endosome transport
0.86	GO:0060766	negative regulation of androgen receptor signaling pathway
0.85	GO:0060391	positive regulation of SMAD protein import into nucleus
0.85	GO:1903077	negative regulation of protein localization to plasma membrane
0.85	GO:1903846	positive regulation of cellular response to transforming growth factor beta stimulus
0.85	GO:0010718	positive regulation of epithelial to mesenchymal transition
0.84	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation

0.84	GO:0035615	clathrin adaptor activity
0.83	GO:0046332	SMAD binding
0.81	GO:0008022	protein C-terminus binding
0.79	GO:0038024	cargo receptor activity
0.54	GO:0035612	AP-2 adaptor complex binding
0.52	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.51	GO:0005178	integrin binding

0.87	GO:0070022	transforming growth factor beta receptor complex
0.79	GO:0001650	fibrillar center
0.79	GO:0005905	clathrin-coated pit
0.77	GO:0030136	clathrin-coated vesicle
0.50	GO:0016324	apical plasma membrane
0.49	GO:0030118	clathrin coat
0.49	GO:0030662	coated vesicle membrane
0.45	GO:0098797	plasma membrane protein complex
0.44	GO:0005925	focal adhesion
0.44	GO:0070062	extracellular exosome

sp|P98088|MUC5A_HUMAN
Mucin-5AC
Search

0.62	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.59	GO:0016266	O-glycan processing
0.56	GO:0048015	phosphatidylinositol-mediated signaling
0.43	GO:0043030	regulation of macrophage activation
0.41	GO:0009617	response to bacterium
0.40	GO:0098542	defense response to other organism
0.39	GO:0030277	maintenance of gastrointestinal epithelium
0.34	GO:0010466	negative regulation of peptidase activity
0.33	GO:0036438	maintenance of lens transparency
0.33	GO:0033189	response to vitamin A

0.56	GO:0005201	extracellular matrix structural constituent
0.37	GO:0005515	protein binding
0.34	GO:0030414	peptidase inhibitor activity

0.66	GO:0005576	extracellular region
0.61	GO:0005796	Golgi lumen
0.51	GO:0031982	vesicle
0.43	GO:0005886	plasma membrane
0.32	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|P98095|FBLN2_HUMAN
Fibulin-2
Search

FBLN2

0.73

Fibulin-2

0.81	GO:0030198	extracellular matrix organization
0.57	GO:0010811	positive regulation of cell-substrate adhesion
0.42	GO:0010952	positive regulation of peptidase activity
0.35	GO:0060317	cardiac epithelial to mesenchymal transition
0.34	GO:1904188	negative regulation of transformation of host cell by virus
0.34	GO:1904235	regulation of substrate-dependent cell migration, cell attachment to substrate
0.34	GO:2001202	negative regulation of transforming growth factor-beta secretion
0.33	GO:0072378	blood coagulation, fibrin clot formation
0.33	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading
0.33	GO:0007566	embryo implantation

0.69	GO:0005509	calcium ion binding
0.56	GO:0050840	extracellular matrix binding
0.43	GO:0016504	peptidase activator activity
0.39	GO:0005201	extracellular matrix structural constituent
0.35	GO:0005515	protein binding
0.33	GO:0044877	macromolecular complex binding

0.74	GO:0031012	extracellular matrix
0.51	GO:0005615	extracellular space
0.42	GO:1903561	extracellular vesicle
0.32	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

sp|P98153|IDD_HUMAN
Integral membrane protein DGCR2/IDD
Search

DGCR2

0.91	DiGeorge syndrome critical region gene 2

0.58	GO:0050890	cognition
0.36	GO:0042493	response to drug

0.30

GO:0044425

membrane part

sp|P98155|VLDLR_HUMAN
Very low-density lipoprotein receptor
Search

VLDLR

0.77	Very low density lipoprotein receptor

0.72	GO:0006898	receptor-mediated endocytosis
0.47	GO:0034436	glycoprotein transport
0.47	GO:0034447	very-low-density lipoprotein particle clearance
0.43	GO:0038026	reelin-mediated signaling pathway
0.42	GO:1900006	positive regulation of dendrite development
0.42	GO:0021517	ventral spinal cord development
0.42	GO:0048813	dendrite morphogenesis
0.41	GO:0045860	positive regulation of protein kinase activity
0.40	GO:0000122	negative regulation of transcription by RNA polymerase II
0.32	GO:0008203	cholesterol metabolic process

0.86	GO:0030229	very-low-density lipoprotein particle receptor activity
0.70	GO:0005509	calcium ion binding
0.47	GO:0034437	glycoprotein transporter activity
0.47	GO:0034189	very-low-density lipoprotein particle binding
0.46	GO:0034185	apolipoprotein binding
0.45	GO:0048306	calcium-dependent protein binding
0.44	GO:0038025	reelin receptor activity
0.30	GO:0005041	low-density lipoprotein receptor activity

0.43	GO:0043235	receptor complex
0.39	GO:0005615	extracellular space
0.33	GO:0044297	cell body
0.32	GO:1990777	lipoprotein particle
0.32	GO:0005905	clathrin-coated pit
0.30	GO:0005774	vacuolar membrane
0.30	GO:0016021	integral component of membrane
0.30	GO:0005764	lysosome
0.30	GO:0071944	cell periphery

sp|P98160|PGBM_HUMAN
Basement membrane-specific heparan sulfate proteoglycan core protein
Search

HSPG2

0.57	Heparan sulfate proteoglycan 2

0.44	GO:0001935	endothelial cell proliferation
0.44	GO:0043534	blood vessel endothelial cell migration
0.43	GO:0014706	striated muscle tissue development
0.43	GO:0060538	skeletal muscle organ development
0.43	GO:0001525	angiogenesis
0.34	GO:0001958	endochondral ossification
0.34	GO:0060351	cartilage development involved in endochondral bone morphogenesis
0.34	GO:0016579	protein deubiquitination
0.34	GO:0002062	chondrocyte differentiation
0.34	GO:0030198	extracellular matrix organization

0.69	GO:0005509	calcium ion binding
0.47	GO:0008022	protein C-terminus binding
0.35	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.34	GO:0070052	collagen V binding
0.34	GO:0002020	protease binding
0.32	GO:0050750	low-density lipoprotein particle receptor binding
0.32	GO:0005178	integrin binding

0.44	GO:0031012	extracellular matrix
0.44	GO:0005615	extracellular space
0.34	GO:0005925	focal adhesion
0.34	GO:1903561	extracellular vesicle
0.33	GO:0005796	Golgi lumen
0.32	GO:0043202	lysosomal lumen
0.32	GO:0098797	plasma membrane protein complex
0.30	GO:0016021	integral component of membrane

sp|P98161|PKD1_HUMAN
Polycystin-1
Search

PKD1

0.82	Polycystin 1, transient receptor potential channel interacting

0.81	GO:0001822	kidney development
0.59	GO:0036303	lymph vessel morphogenesis
0.58	GO:0050982	detection of mechanical stimulus
0.58	GO:0031659	positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle
0.57	GO:0042994	cytoplasmic sequestering of transcription factor
0.57	GO:0001889	liver development
0.57	GO:0001502	cartilage condensation
0.57	GO:0034405	response to fluid shear stress
0.56	GO:0060428	lung epithelium development
0.56	GO:0006611	protein export from nucleus

0.55	GO:0044325	ion channel binding
0.55	GO:0005262	calcium channel activity
0.52	GO:0019901	protein kinase binding
0.51	GO:0019904	protein domain specific binding
0.39	GO:0030246	carbohydrate binding

0.59	GO:0002133	polycystin complex
0.54	GO:0016323	basolateral plasma membrane
0.53	GO:0070062	extracellular exosome
0.53	GO:0031514	motile cilium
0.51	GO:0009986	cell surface
0.44	GO:0005634	nucleus
0.43	GO:0060170	ciliary membrane
0.43	GO:0016328	lateral plasma membrane
0.41	GO:0030660	Golgi-associated vesicle membrane
0.40	GO:0000139	Golgi membrane

sp|P98164|LRP2_HUMAN
Low-density lipoprotein receptor-related protein 2
Search

0.74	Low density lipoprotein receptor-related protein 2a

0.75	GO:0070293	renal absorption
0.61	GO:0006898	receptor-mediated endocytosis

0.70

GO:0005509

calcium ion binding

0.30

GO:0044425

membrane part

sp|P98168|ZXDA_HUMAN
Zinc finger X-linked protein ZXDA
Search

ZXDC

0.90	Zinc finger X-linked protein ZXDB

0.49	GO:0045893	positive regulation of transcription, DNA-templated
0.35	GO:0006351	transcription, DNA-templated

0.57	GO:0070742	C2H2 zinc finger domain binding
0.56	GO:0030275	LRR domain binding
0.51	GO:0003676	nucleic acid binding
0.44	GO:0003700	DNA binding transcription factor activity
0.38	GO:0016153	urocanate hydratase activity
0.34	GO:0046872	metal ion binding

0.36	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.38	EC:4.2.1.49	GO:0016153
0.38	KEGG:R02914	GO:0016153

sp|P98169|ZXDB_HUMAN
Zinc finger X-linked protein ZXDB
Search

ZXDC

0.90	Zinc finger X-linked protein ZXDB

0.49	GO:0045893	positive regulation of transcription, DNA-templated
0.35	GO:0006351	transcription, DNA-templated

0.57	GO:0070742	C2H2 zinc finger domain binding
0.56	GO:0030275	LRR domain binding
0.51	GO:0003676	nucleic acid binding
0.44	GO:0003700	DNA binding transcription factor activity
0.38	GO:0016153	urocanate hydratase activity
0.34	GO:0046872	metal ion binding

0.36	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.38	EC:4.2.1.49	GO:0016153
0.38	KEGG:R02914	GO:0016153

sp|P98170|XIAP_HUMAN
E3 ubiquitin-protein ligase XIAP
Search

XIAP

0.91	Baculoviral IAP repeat-containing protein 4

0.79	GO:1990001	inhibition of cysteine-type endopeptidase activity involved in apoptotic process
0.73	GO:0006915	apoptotic process
0.71	GO:0070997	neuron death
0.70	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.69	GO:1902530	positive regulation of protein linear polyubiquitination
0.63	GO:0016567	protein ubiquitination
0.56	GO:0090307	mitotic spindle assembly
0.50	GO:0006974	cellular response to DNA damage stimulus
0.46	GO:0070247	regulation of natural killer cell apoptotic process
0.41	GO:0042127	regulation of cell proliferation

0.74	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process
0.64	GO:0004842	ubiquitin-protein transferase activity
0.56	GO:0042802	identical protein binding
0.41	GO:0016874	ligase activity
0.41	GO:0003735	structural constituent of ribosome
0.39	GO:0046872	metal ion binding

0.54	GO:0005634	nucleus
0.48	GO:0005737	cytoplasm
0.42	GO:0043232	intracellular non-membrane-bounded organelle
0.40	GO:0030529	intracellular ribonucleoprotein complex
0.39	GO:0012505	endomembrane system
0.37	GO:0044446	intracellular organelle part

0.41	EC:6	GO:0016874
0.64	KEGG:R03876	GO:0004842

sp|P98171|RHG04_HUMAN
Rho GTPase-activating protein 4
Search

ARHGAP4

0.86	SLIT-ROBO Rho GTPase activating protein 3

0.74	GO:0043547	positive regulation of GTPase activity
0.60	GO:0007165	signal transduction
0.52	GO:0030336	negative regulation of cell migration
0.43	GO:0010762	regulation of fibroblast migration
0.43	GO:0030517	negative regulation of axon extension
0.39	GO:0051056	regulation of small GTPase mediated signal transduction
0.36	GO:0009967	positive regulation of signal transduction
0.35	GO:0007010	cytoskeleton organization

0.75	GO:0005096	GTPase activator activity
0.52	GO:0048365	Rac GTPase binding
0.46	GO:0042802	identical protein binding
0.37	GO:0005070	SH3/SH2 adaptor activity
0.35	GO:0008080	N-acetyltransferase activity

0.42	GO:0030426	growth cone
0.41	GO:0005737	cytoplasm
0.40	GO:0005874	microtubule
0.38	GO:0012505	endomembrane system
0.36	GO:0043231	intracellular membrane-bounded organelle
0.33	GO:0034708	methyltransferase complex
0.33	GO:0043233	organelle lumen

0.35

GO:0008080

sp|P98172|EFNB1_HUMAN
Ephrin-B1
Search

0.74	GO:0048013	ephrin receptor signaling pathway
0.61	GO:0031295	T cell costimulation
0.58	GO:0001667	ameboidal-type cell migration
0.56	GO:0007411	axon guidance
0.56	GO:0008284	positive regulation of cell proliferation
0.55	GO:0009888	tissue development
0.54	GO:0048513	animal organ development
0.54	GO:0048864	stem cell development
0.53	GO:0042129	regulation of T cell proliferation
0.53	GO:0009880	embryonic pattern specification

0.76	GO:0046875	ephrin receptor binding
0.34	GO:0016301	kinase activity

0.52	GO:0045121	membrane raft
0.45	GO:0005886	plasma membrane
0.44	GO:0005634	nucleus
0.38	GO:0005737	cytoplasm
0.37	GO:0070062	extracellular exosome
0.36	GO:0045202	synapse
0.34	GO:0005925	focal adhesion
0.30	GO:0016021	integral component of membrane

sp|P98173|FAM3A_HUMAN
Protein FAM3A
Search

FAM3A

0.54	Family 3, member A protein isoform 1

0.48	GO:0046676	negative regulation of insulin secretion
0.43	GO:1905035	negative regulation of antifungal innate immune response
0.41	GO:0019732	antifungal humoral response
0.40	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.37	GO:0006098	pentose-phosphate shunt
0.37	GO:0006006	glucose metabolic process
0.34	GO:0055114	oxidation-reduction process
0.34	GO:0010469	regulation of receptor activity
0.34	GO:0055085	transmembrane transport
0.34	GO:0009062	fatty acid catabolic process

0.38	GO:0004345	glucose-6-phosphate dehydrogenase activity
0.37	GO:0050661	NADP binding
0.35	GO:0033791	3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity
0.34	GO:0005125	cytokine activity
0.34	GO:0003997	acyl-CoA oxidase activity
0.33	GO:0050660	flavin adenine dinucleotide binding

0.37	GO:0005576	extracellular region
0.34	GO:0042579	microbody
0.30	GO:0016021	integral component of membrane

0.38

EC:1.1.1.49

GO:0004345

sp|P98174|FGD1_HUMAN
FYVE, RhoGEF and PH domain-containing protein 1
Search

FGD1

0.94	FYVE, RhoGEF and PH domain-containing protein 1

0.77	GO:0035023	regulation of Rho protein signal transduction
0.66	GO:0065009	regulation of molecular function
0.64	GO:0046847	filopodium assembly
0.55	GO:0030036	actin cytoskeleton organization
0.53	GO:0008360	regulation of cell shape
0.36	GO:0043065	positive regulation of apoptotic process
0.36	GO:0009887	animal organ morphogenesis
0.35	GO:0007186	G-protein coupled receptor signaling pathway

0.77	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.53	GO:0046872	metal ion binding

0.60	GO:0001726	ruffle
0.60	GO:0030027	lamellipodium
0.54	GO:0005794	Golgi apparatus
0.37	GO:0005856	cytoskeleton
0.35	GO:0005829	cytosol
0.30	GO:0016020	membrane

sp|P98175|RBM10_HUMAN
RNA-binding protein 10
Search

RBM10

0.95	RNA binding motif protein 5

0.82	GO:0000381	regulation of alternative mRNA splicing, via spliceosome
0.73	GO:0042981	regulation of apoptotic process
0.72	GO:0008380	RNA splicing
0.57	GO:0070935	3'-UTR-mediated mRNA stabilization
0.57	GO:0048025	negative regulation of mRNA splicing, via spliceosome
0.54	GO:0043068	positive regulation of programmed cell death
0.52	GO:0008285	negative regulation of cell proliferation
0.52	GO:0000122	negative regulation of transcription by RNA polymerase II
0.39	GO:0006397	mRNA processing
0.38	GO:0022618	ribonucleoprotein complex assembly

0.58	GO:0003723	RNA binding
0.52	GO:0046872	metal ion binding
0.38	GO:0032403	protein complex binding
0.38	GO:0042802	identical protein binding

0.55	GO:0016607	nuclear speck
0.43	GO:0005681	spliceosomal complex
0.30	GO:0031224	intrinsic component of membrane

sp|P98177|FOXO4_HUMAN
Forkhead box protein O4
Search

FOXO4

0.97	Fork head domain transcription factor AFX1

0.65	GO:0051151	negative regulation of smooth muscle cell differentiation
0.64	GO:0070317	negative regulation of G0 to G1 transition
0.63	GO:0071158	positive regulation of cell cycle arrest
0.63	GO:0007095	mitotic G2 DNA damage checkpoint
0.62	GO:0008286	insulin receptor signaling pathway
0.61	GO:0016525	negative regulation of angiogenesis
0.60	GO:0007050	cell cycle arrest
0.60	GO:0048863	stem cell differentiation
0.58	GO:0008285	negative regulation of cell proliferation
0.57	GO:2001141	regulation of RNA biosynthetic process

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.61	GO:0008013	beta-catenin binding
0.55	GO:0042802	identical protein binding
0.54	GO:0008134	transcription factor binding
0.54	GO:0019899	enzyme binding
0.44	GO:1990841	promoter-specific chromatin binding
0.33	GO:0000989	transcription factor activity, transcription factor binding

0.61	GO:0005634	nucleus
0.52	GO:0005829	cytosol
0.51	GO:0070013	intracellular organelle lumen
0.45	GO:0044446	intracellular organelle part

sp|P98179|RBM3_HUMAN
RNA-binding protein 3
Search

RBM3

0.41	Cold-inducible RNA-binding protein isoform B

0.47	GO:0034063	stress granule assembly
0.47	GO:0009409	response to cold
0.45	GO:0030308	negative regulation of cell growth
0.45	GO:1902806	regulation of cell cycle G1/S phase transition
0.45	GO:0017148	negative regulation of translation
0.41	GO:0045727	positive regulation of translation
0.40	GO:0033554	cellular response to stress
0.39	GO:0048255	mRNA stabilization
0.38	GO:0009411	response to UV
0.37	GO:0070918	production of small RNA involved in gene silencing by RNA

0.59	GO:0003723	RNA binding
0.47	GO:0030371	translation repressor activity
0.37	GO:0043023	ribosomal large subunit binding
0.35	GO:0005515	protein binding
0.35	GO:0047750	cholestenol delta-isomerase activity
0.32	GO:0003677	DNA binding

0.51	GO:0005730	nucleolus
0.49	GO:0005654	nucleoplasm
0.45	GO:0010494	cytoplasmic stress granule
0.39	GO:0030425	dendrite
0.36	GO:0015934	large ribosomal subunit
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:5.3.3.5

GO:0047750

sp|P98182|ZN200_HUMAN
Zinc finger protein 200
Search

ZNF200

0.97	LOW QUALITY PROTEIN: zinc finger protein 200

0.40	GO:1903506	regulation of nucleic acid-templated transcription
0.40	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.40	GO:0010468	regulation of gene expression
0.36	GO:0006351	transcription, DNA-templated
0.33	GO:1902680	positive regulation of RNA biosynthetic process

0.51	GO:0003676	nucleic acid binding
0.39	GO:0046872	metal ion binding
0.37	GO:0003700	DNA binding transcription factor activity

0.42	GO:0005634	nucleus
0.33	GO:0031974	membrane-enclosed lumen
0.32	GO:0043232	intracellular non-membrane-bounded organelle
0.32	GO:0044446	intracellular organelle part

sp|P98187|CP4F8_HUMAN
Cytochrome P450 4F8
Search

0.95	Cytochrome P450 family 4 subfamily F member 8

0.58	GO:0036102	leukotriene B4 metabolic process
0.58	GO:0036100	leukotriene catabolic process
0.55	GO:0042758	long-chain fatty acid catabolic process
0.55	GO:0003095	pressure natriuresis
0.55	GO:0006775	fat-soluble vitamin metabolic process
0.53	GO:0055114	oxidation-reduction process
0.52	GO:0003091	renal water homeostasis
0.52	GO:0019373	epoxygenase P450 pathway
0.51	GO:0055078	sodium ion homeostasis
0.50	GO:0000038	very long-chain fatty acid metabolic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.68	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.46	GO:0005504	fatty acid binding
0.38	GO:0019825	oxygen binding
0.33	GO:0003676	nucleic acid binding

0.49	GO:0016324	apical plasma membrane
0.39	GO:0043231	intracellular membrane-bounded organelle
0.37	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.37	GO:0005737	cytoplasm
0.36	GO:0031984	organelle subcompartment
0.35	GO:0031090	organelle membrane
0.30	GO:0016021	integral component of membrane

0.68

GO:0016705

sp|P98194|AT2C1_HUMAN
Calcium-transporting ATPase type 2C member 1
Search

ATP2C1

0.55	Calcium-transporting ATPase

0.76	GO:0070588	calcium ion transmembrane transport
0.68	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.56	GO:0032472	Golgi calcium ion transport
0.55	GO:0032468	Golgi calcium ion homeostasis
0.53	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
0.51	GO:0008544	epidermis development
0.49	GO:0031532	actin cytoskeleton reorganization
0.40	GO:0030026	cellular manganese ion homeostasis
0.40	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.40	GO:0071421	manganese ion transmembrane transport

0.79	GO:0005388	calcium-transporting ATPase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0015410	manganese-transporting ATPase activity
0.38	GO:0030145	manganese ion binding
0.37	GO:0005509	calcium ion binding
0.36	GO:0004871	signal transducer activity
0.34	GO:0009013	succinate-semialdehyde dehydrogenase [NAD(P)+] activity

0.50	GO:0005802	trans-Golgi network
0.48	GO:0000139	Golgi membrane
0.34	GO:0030141	secretory granule
0.34	GO:0031985	Golgi cisterna
0.34	GO:0030133	transport vesicle
0.32	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.79

EC:3.6.3.8

GO:0005388

sp|P98196|AT11A_HUMAN
Probable phospholipid-transporting ATPase IH
Search

ATP11A

0.59	Phospholipid-transporting ATPase

0.80	GO:0045332	phospholipid translocation
0.35	GO:0035023	regulation of Rho protein signal transduction
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0065009	regulation of molecular function
0.34	GO:0035556	intracellular signal transduction

0.80	GO:0004012	phospholipid-translocating ATPase activity
0.64	GO:0000287	magnesium ion binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.33	GO:0008270	zinc ion binding

0.52	GO:0055037	recycling endosome
0.46	GO:0005783	endoplasmic reticulum
0.38	GO:0005886	plasma membrane
0.37	GO:0005765	lysosomal membrane
0.36	GO:0005769	early endosome
0.35	GO:0035579	specific granule membrane
0.35	GO:0070821	tertiary granule membrane
0.30	GO:0016021	integral component of membrane

0.80

EC:3.6.3.1

GO:0004012

sp|P98198|AT8B2_HUMAN
Phospholipid-transporting ATPase ID
Search

ATP8B2

0.59	Phospholipid-transporting ATPase ID

0.80	GO:0045332	phospholipid translocation
0.50	GO:0007030	Golgi organization
0.35	GO:0043312	neutrophil degranulation
0.34	GO:0006833	water transport
0.33	GO:0055085	transmembrane transport

0.81	GO:0004012	phospholipid-translocating ATPase activity
0.64	GO:0000287	magnesium ion binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0022803	passive transmembrane transporter activity
0.33	GO:0005515	protein binding

0.54	GO:0005794	Golgi apparatus
0.45	GO:0005886	plasma membrane
0.35	GO:0005789	endoplasmic reticulum membrane
0.35	GO:0035579	specific granule membrane
0.35	GO:0070821	tertiary granule membrane
0.30	GO:0031224	intrinsic component of membrane

0.81

EC:3.6.3.1

GO:0004012

sp|P99999|CYC_HUMAN
Cytochrome c
Search

CYCS

0.65	Cytochrome c, somatic

0.61	GO:0022900	electron transport chain
0.51	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.43	GO:0006915	apoptotic process
0.43	GO:0010730	negative regulation of hydrogen peroxide biosynthetic process
0.43	GO:0042743	hydrogen peroxide metabolic process
0.43	GO:0006119	oxidative phosphorylation
0.43	GO:0009060	aerobic respiration
0.43	GO:0034465	response to carbon monoxide
0.42	GO:1901857	positive regulation of cellular respiration
0.42	GO:0002931	response to ischemia

0.63	GO:0020037	heme binding
0.62	GO:0009055	electron transfer activity
0.54	GO:0046872	metal ion binding
0.38	GO:0019899	enzyme binding

0.62	GO:0070469	respiratory chain
0.61	GO:0005739	mitochondrion
0.55	GO:0031970	organelle envelope lumen
0.48	GO:0005829	cytosol
0.45	GO:0005634	nucleus
0.45	GO:0043209	myelin sheath

sp|Q00005|2ABB_HUMAN
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform
Search

PPP2R2B

0.66	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B

0.78	GO:0043666	regulation of phosphoprotein phosphatase activity
0.47	GO:0070262	peptidyl-serine dephosphorylation
0.44	GO:0000278	mitotic cell cycle
0.41	GO:0032502	developmental process
0.37	GO:0006915	apoptotic process
0.35	GO:0043525	positive regulation of neuron apoptotic process
0.35	GO:0000266	mitochondrial fission
0.34	GO:0007283	spermatogenesis
0.34	GO:0022412	cellular process involved in reproduction in multicellular organism
0.34	GO:0006626	protein targeting to mitochondrion

0.80	GO:0019888	protein phosphatase regulator activity
0.44	GO:0004722	protein serine/threonine phosphatase activity
0.34	GO:0005515	protein binding
0.34	GO:0044877	macromolecular complex binding

0.81	GO:0000159	protein phosphatase type 2A complex
0.42	GO:0005829	cytosol
0.40	GO:0005856	cytoskeleton
0.37	GO:0005741	mitochondrial outer membrane

sp|Q00013|EM55_HUMAN
55 kDa erythrocyte membrane protein
Search

MPP1

0.97	Membrane palmitoylated protein 1

0.85	GO:0090022	regulation of neutrophil chemotaxis
0.38	GO:0046710	GDP metabolic process
0.38	GO:0046037	GMP metabolic process
0.38	GO:0016310	phosphorylation
0.37	GO:0036211	protein modification process
0.36	GO:0044267	cellular protein metabolic process
0.35	GO:0007165	signal transduction

0.40	GO:0016301	kinase activity
0.38	GO:0005515	protein binding
0.37	GO:0016773	phosphotransferase activity, alcohol group as acceptor
0.37	GO:0016776	phosphotransferase activity, phosphate group as acceptor
0.36	GO:0140096	catalytic activity, acting on a protein
0.36	GO:0005524	ATP binding

0.77	GO:0030863	cortical cytoskeleton
0.76	GO:0016607	nuclear speck
0.65	GO:0005829	cytosol
0.52	GO:0032420	stereocilium
0.36	GO:0005887	integral component of plasma membrane

0.37

GO:0016773

sp|Q00056|HXA4_HUMAN
Homeobox protein Hox-A4
Search

0.92	Homeobox protein Hox-A4

0.65	GO:0007275	multicellular organism development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.47	GO:0048863	stem cell differentiation
0.44	GO:0009653	anatomical structure morphogenesis
0.44	GO:0006366	transcription by RNA polymerase II
0.44	GO:1902680	positive regulation of RNA biosynthetic process

0.64	GO:0043565	sequence-specific DNA binding
0.57	GO:0003700	DNA binding transcription factor activity
0.45	GO:0001012	RNA polymerase II regulatory region DNA binding
0.43	GO:0003690	double-stranded DNA binding
0.32	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.50	GO:0031974	membrane-enclosed lumen
0.45	GO:0044446	intracellular organelle part
0.44	GO:0030054	cell junction

sp|Q00059|TFAM_HUMAN
Transcription factor A, mitochondrial
Search

TFAM

0.93	Mitochondrial transcription factor A

0.63	GO:0006391	transcription initiation from mitochondrial promoter
0.55	GO:0033108	mitochondrial respiratory chain complex assembly
0.54	GO:0045893	positive regulation of transcription, DNA-templated
0.51	GO:0006357	regulation of transcription by RNA polymerase II
0.37	GO:0006356	regulation of transcription by RNA polymerase I
0.36	GO:0006261	DNA-dependent DNA replication
0.36	GO:0032042	mitochondrial DNA metabolic process
0.36	GO:0006366	transcription by RNA polymerase II
0.33	GO:0022900	electron transport chain

0.65	GO:0001018	mitochondrial promoter sequence-specific DNA binding
0.61	GO:0008301	DNA binding, bending
0.56	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.56	GO:0003682	chromatin binding
0.48	GO:0003700	DNA binding transcription factor activity
0.43	GO:0001223	transcription coactivator binding
0.40	GO:0031072	heat shock protein binding
0.35	GO:0003723	RNA binding
0.33	GO:0009055	electron transfer activity

0.61	GO:0005634	nucleus
0.60	GO:0042645	mitochondrial nucleoid
0.36	GO:0005829	cytosol
0.35	GO:0005667	transcription factor complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q00169|PIPNA_HUMAN
Phosphatidylinositol transfer protein alpha isoform
Search

PITPNA

0.96	Phosphatidylinositol transfer protein alpha

0.77	GO:0015914	phospholipid transport
0.52	GO:0007409	axonogenesis
0.36	GO:0043009	chordate embryonic development
0.36	GO:0035722	interleukin-12-mediated signaling pathway
0.34	GO:0007601	visual perception
0.33	GO:0006629	lipid metabolic process

0.78	GO:0005548	phospholipid transporter activity
0.56	GO:0031210	phosphatidylcholine binding
0.50	GO:0035091	phosphatidylinositol binding
0.36	GO:0070540	stearic acid binding
0.35	GO:1901611	phosphatidylglycerol binding
0.35	GO:0000062	fatty-acyl-CoA binding

0.52	GO:0043209	myelin sheath
0.44	GO:0005622	intracellular
0.36	GO:0070062	extracellular exosome
0.33	GO:0012505	endomembrane system
0.32	GO:0044422	organelle part
0.30	GO:0016020	membrane

sp|Q00266|METK1_HUMAN
S-adenosylmethionine synthase isoform type-1
Search

MAT1A

0.54	S-adenosylmethionine synthase

0.78	GO:0006556	S-adenosylmethionine biosynthetic process
0.72	GO:0006730	one-carbon metabolic process
0.60	GO:0009087	methionine catabolic process
0.55	GO:0051289	protein homotetramerization
0.52	GO:0034214	protein hexamerization
0.50	GO:0051291	protein heterooligomerization
0.49	GO:1990830	cellular response to leukemia inhibitory factor
0.39	GO:0055013	cardiac muscle cell development
0.38	GO:0072358	cardiovascular system development
0.35	GO:0001887	selenium compound metabolic process

0.78	GO:0004478	methionine adenosyltransferase activity
0.55	GO:0042802	identical protein binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0046872	metal ion binding
0.36	GO:0098601	selenomethionine adenosyltransferase activity
0.34	GO:0016597	amino acid binding
0.33	GO:0046983	protein dimerization activity

0.54	GO:0048269	methionine adenosyltransferase complex
0.44	GO:0005829	cytosol
0.35	GO:0016363	nuclear matrix

0.78

EC:2.5.1.6

GO:0004478

sp|Q00325|MPCP_HUMAN
Phosphate carrier protein, mitochondrial
Search

SLC25A3

0.84	Mitochondrial inorganic phosphate carrier

0.45	GO:0006839	mitochondrial transport
0.44	GO:0035435	phosphate ion transmembrane transport
0.34	GO:1902600	hydrogen ion transmembrane transport

0.49	GO:0032403	protein complex binding
0.45	GO:0015114	phosphate ion transmembrane transporter activity
0.38	GO:0015317	phosphate:proton symporter activity

0.52	GO:0043209	myelin sheath
0.45	GO:0005743	mitochondrial inner membrane
0.36	GO:0070062	extracellular exosome
0.33	GO:0005887	integral component of plasma membrane

sp|Q00341|VIGLN_HUMAN
Vigilin
Search

HDLBP

0.93	High density lipoprotein-binding protein vigilin

0.47	GO:0071391	cellular response to estrogen stimulus
0.40	GO:0008203	cholesterol metabolic process
0.39	GO:0006869	lipid transport
0.36	GO:0034384	high-density lipoprotein particle clearance

0.59	GO:0003723	RNA binding
0.39	GO:0045296	cadherin binding
0.34	GO:0008289	lipid binding

0.49	GO:0005829	cytosol
0.41	GO:0034364	high-density lipoprotein particle
0.36	GO:0005634	nucleus
0.33	GO:0005886	plasma membrane

sp|Q00403|TF2B_HUMAN
Transcription initiation factor IIB
Search

GTF2B

0.60	Transcription initiation factor IIB

0.79	GO:0070897	DNA-templated transcriptional preinitiation complex assembly
0.60	GO:0006413	translational initiation
0.57	GO:1904798	positive regulation of core promoter binding
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.52	GO:0050434	positive regulation of viral transcription
0.52	GO:0006367	transcription initiation from RNA polymerase II promoter
0.35	GO:0042795	snRNA transcription by RNA polymerase II
0.34	GO:0097052	L-kynurenine metabolic process

0.80	GO:0017025	TBP-class protein binding
0.61	GO:0003743	translation initiation factor activity
0.56	GO:0046966	thyroid hormone receptor binding
0.55	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding
0.52	GO:0046872	metal ion binding
0.35	GO:0036137	kynurenine aminotransferase activity
0.33	GO:0030170	pyridoxal phosphate binding

0.56	GO:0097550	transcriptional preinitiation complex
0.52	GO:0005669	transcription factor TFIID complex
0.51	GO:0016604	nuclear body
0.34	GO:0000145	exocyst
0.30	GO:0016020	membrane

sp|Q00444|HXC5_HUMAN
Homeobox protein Hox-C5
Search

HOXC5

0.71	Homeobox protein Hox-C5

0.65	GO:0007275	multicellular organism development
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.36	GO:0006351	transcription, DNA-templated

0.61	GO:0043565	sequence-specific DNA binding
0.60	GO:0003700	DNA binding transcription factor activity

0.59	GO:0005634	nucleus
0.42	GO:0030054	cell junction
0.40	GO:0031974	membrane-enclosed lumen
0.37	GO:0044446	intracellular organelle part

sp|Q00526|CDK3_HUMAN
Cyclin-dependent kinase 3
Search

CDK3

0.90	Porcine cyclin dependent kinase 2

0.62	GO:0006468	protein phosphorylation
0.54	GO:0000082	G1/S transition of mitotic cell cycle
0.53	GO:0008284	positive regulation of cell proliferation
0.52	GO:0051726	regulation of cell cycle
0.51	GO:0032298	positive regulation of DNA-dependent DNA replication initiation
0.49	GO:0007099	centriole replication
0.48	GO:0018209	peptidyl-serine modification
0.48	GO:0007265	Ras protein signal transduction
0.48	GO:0060968	regulation of gene silencing
0.47	GO:0000122	negative regulation of transcription by RNA polymerase II

0.67	GO:0004674	protein serine/threonine kinase activity
0.57	GO:0097472	cyclin-dependent protein kinase activity
0.54	GO:0030554	adenyl nucleotide binding
0.54	GO:0030332	cyclin binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0008144	drug binding
0.50	GO:0035173	histone kinase activity
0.46	GO:0019904	protein domain specific binding
0.35	GO:0032403	protein complex binding

0.56	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.52	GO:0000806	Y chromosome
0.50	GO:0000805	X chromosome
0.50	GO:0015030	Cajal body
0.47	GO:0005815	microtubule organizing center
0.47	GO:0000781	chromosome, telomeric region
0.46	GO:0005768	endosome
0.46	GO:0005667	transcription factor complex
0.46	GO:0000793	condensed chromosome
0.35	GO:0000235	astral microtubule

0.67

GO:0004674

sp|Q00532|CDKL1_HUMAN
Cyclin-dependent kinase-like 1
Search

CDKL1

0.96	Cyclin dependent kinase like 1

0.63	GO:0006468	protein phosphorylation
0.45	GO:0051726	regulation of cell cycle
0.38	GO:0007507	heart development
0.32	GO:0055114	oxidation-reduction process

0.66	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0097472	cyclin-dependent protein kinase activity
0.32	GO:0016491	oxidoreductase activity

0.48	GO:0005654	nucleoplasm
0.36	GO:0070062	extracellular exosome
0.33	GO:0005737	cytoplasm

0.66

GO:0004674

sp|Q00534|CDK6_HUMAN
Cyclin-dependent kinase 6
Search

CDK6

0.97	Cell division protein kinase 6

0.76	GO:0043697	cell dedifferentiation
0.67	GO:0042127	regulation of cell proliferation
0.65	GO:0051726	regulation of cell cycle
0.62	GO:0006468	protein phosphorylation
0.61	GO:1904628	cellular response to phorbol 13-acetate 12-myristate
0.59	GO:0007049	cell cycle
0.58	GO:0045656	negative regulation of monocyte differentiation
0.57	GO:2000773	negative regulation of cellular senescence
0.57	GO:0003323	type B pancreatic cell development
0.56	GO:0045668	negative regulation of osteoblast differentiation

0.74	GO:0004693	cyclin-dependent protein serine/threonine kinase activity
0.59	GO:0098770	FBXO family protein binding
0.59	GO:0030332	cyclin binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0008144	drug binding
0.34	GO:0032403	protein complex binding
0.33	GO:0005509	calcium ion binding

0.59	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.54	GO:0001726	ruffle
0.52	GO:0005813	centrosome
0.49	GO:0005829	cytosol
0.49	GO:0031981	nuclear lumen
0.41	GO:0005923	bicellular tight junction
0.41	GO:0031965	nuclear membrane
0.40	GO:0005667	transcription factor complex
0.39	GO:0000785	chromatin
0.34	GO:0048471	perinuclear region of cytoplasm

0.74

EC:2.7.11.22

GO:0004693

sp|Q00535|CDK5_HUMAN
Cyclin-dependent-like kinase 5
Search

CDK5

0.88	Cyclin-dependent protein kinase 5

0.61	GO:0006468	protein phosphorylation
0.59	GO:0021954	central nervous system neuron development
0.58	GO:0007422	peripheral nervous system development
0.58	GO:0031914	negative regulation of synaptic plasticity
0.58	GO:1901214	regulation of neuron death
0.57	GO:0046826	negative regulation of protein export from nucleus
0.57	GO:0051402	neuron apoptotic process
0.57	GO:0022038	corpus callosum development
0.57	GO:0021819	layer formation in cerebral cortex
0.56	GO:0001963	synaptic transmission, dopaminergic

0.66	GO:0004674	protein serine/threonine kinase activity
0.59	GO:0030549	acetylcholine receptor activator activity
0.59	GO:0043125	ErbB-3 class receptor binding
0.57	GO:0005176	ErbB-2 class receptor binding
0.54	GO:0002039	p53 binding
0.53	GO:0030554	adenyl nucleotide binding
0.53	GO:0097472	cyclin-dependent protein kinase activity
0.52	GO:0097367	carbohydrate derivative binding
0.52	GO:0008144	drug binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding

0.54	GO:0030175	filopodium
0.54	GO:0030027	lamellipodium
0.53	GO:0030424	axon
0.52	GO:0045202	synapse
0.50	GO:0030054	cell junction
0.49	GO:0005829	cytosol
0.45	GO:0005634	nucleus
0.42	GO:0030426	growth cone
0.42	GO:0005886	plasma membrane
0.42	GO:0043025	neuronal cell body

0.66

GO:0004674

sp|Q00536|CDK16_HUMAN
Cyclin-dependent kinase 16
Search

CDK16

0.94	PCTAIRE-motif protein kinase 1

0.63	GO:0006468	protein phosphorylation
0.56	GO:0030252	growth hormone secretion
0.55	GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus
0.51	GO:0031175	neuron projection development
0.51	GO:0006887	exocytosis
0.51	GO:0007283	spermatogenesis
0.36	GO:0051726	regulation of cell cycle
0.36	GO:0051301	cell division
0.33	GO:0016579	protein deubiquitination
0.33	GO:0006511	ubiquitin-dependent protein catabolic process

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.42	GO:0060089	molecular transducer activity
0.35	GO:0005515	protein binding
0.33	GO:0004843	thiol-dependent ubiquitin-specific protease activity

0.53	GO:0008021	synaptic vesicle
0.52	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.49	GO:0015630	microtubule cytoskeleton
0.48	GO:0005829	cytosol
0.40	GO:0005634	nucleus
0.37	GO:0043005	neuron projection
0.37	GO:0030054	cell junction

sp|Q00537|CDK17_HUMAN
Cyclin-dependent kinase 17
Search

CDK17

0.96	Serine/threonine-protein kinase PCTAIRE-2

0.63	GO:0006468	protein phosphorylation
0.36	GO:0051301	cell division
0.34	GO:0031175	neuron projection development
0.34	GO:0006887	exocytosis

0.64	GO:0004672	protein kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.41	GO:0060089	molecular transducer activity
0.33	GO:0005515	protein binding

0.40	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm
0.34	GO:0098793	presynapse
0.33	GO:0097708	intracellular vesicle
0.33	GO:0012505	endomembrane system
0.30	GO:0016020	membrane

sp|Q00577|PURA_HUMAN
Transcriptional activator protein Pur-alpha
Search

PURA

0.95	Transcriptional activator protein Pur-alpha

0.72	GO:0030154	cell differentiation
0.71	GO:0045892	negative regulation of transcription, DNA-templated
0.69	GO:0042127	regulation of cell proliferation
0.57	GO:0008283	cell proliferation
0.51	GO:0006268	DNA unwinding involved in DNA replication
0.50	GO:0017148	negative regulation of translation
0.49	GO:0007399	nervous system development
0.47	GO:0048522	positive regulation of cellular process
0.40	GO:0006357	regulation of transcription by RNA polymerase II
0.36	GO:0006915	apoptotic process

0.61	GO:0003700	DNA binding transcription factor activity
0.57	GO:0032422	purine-rich negative regulatory element binding
0.57	GO:0003691	double-stranded telomeric DNA binding
0.56	GO:0046332	SMAD binding
0.55	GO:0003723	RNA binding
0.55	GO:0000900	translation repressor activity, nucleic acid binding
0.52	GO:0003697	single-stranded DNA binding
0.52	GO:0008134	transcription factor binding
0.40	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.33	GO:0016675	oxidoreductase activity, acting on a heme group of donors

0.59	GO:0005662	DNA replication factor A complex
0.51	GO:0043025	neuronal cell body
0.51	GO:0030425	dendrite
0.38	GO:0005737	cytoplasm
0.35	GO:0000784	nuclear chromosome, telomeric region
0.33	GO:0031967	organelle envelope
0.30	GO:0016020	membrane

0.33

EC:1.9

GO:0016675

sp|Q00587|BORG5_HUMAN
Cdc42 effector protein 1
Search

CDC42EP1

0.95	CDC42 effector protein (Rho GTPase binding) 1

0.86	GO:0031274	positive regulation of pseudopodium assembly
0.75	GO:0098609	cell-cell adhesion
0.69	GO:0008360	regulation of cell shape
0.68	GO:0007266	Rho protein signal transduction
0.64	GO:0030838	positive regulation of actin filament polymerization
0.61	GO:0043547	positive regulation of GTPase activity
0.35	GO:0071346	cellular response to interferon-gamma
0.32	GO:0022900	electron transport chain

0.85	GO:0098641	cadherin binding involved in cell-cell adhesion
0.69	GO:0017049	GTP-Rho binding
0.62	GO:0005096	GTPase activator activity
0.33	GO:0003723	RNA binding
0.32	GO:0009055	electron transfer activity

0.81	GO:0005913	cell-cell adherens junction
0.48	GO:0005925	focal adhesion
0.48	GO:0005886	plasma membrane
0.46	GO:0005856	cytoskeleton
0.45	GO:0012505	endomembrane system
0.43	GO:0005737	cytoplasm
0.34	GO:0097708	intracellular vesicle
0.30	GO:0016021	integral component of membrane

sp|Q00597|FANCC_HUMAN
Fanconi anemia group C protein
Search

FANCC

0.97	Fanconi anemia complementation group C

0.64	GO:0006281	DNA repair
0.62	GO:0097150	neuronal stem cell population maintenance
0.61	GO:0048854	brain morphogenesis
0.60	GO:0002262	myeloid cell homeostasis
0.58	GO:0007281	germ cell development
0.57	GO:0034599	cellular response to oxidative stress
0.55	GO:0000303	response to superoxide
0.55	GO:0006801	superoxide metabolic process
0.54	GO:1901701	cellular response to oxygen-containing compound
0.52	GO:0098869	cellular oxidant detoxification

0.35

GO:0005515

protein binding

0.78	GO:0043240	Fanconi anaemia nuclear complex
0.51	GO:0005829	cytosol
0.35	GO:0000785	chromatin

sp|Q00604|NDP_HUMAN
Norrin
Search

NDP

0.97	NDP, norrin cystine knot growth factor

0.77	GO:0016055	Wnt signaling pathway
0.64	GO:0061298	retina vasculature development in camera-type eye
0.63	GO:0035426	extracellular matrix-cell signaling
0.57	GO:0051091	positive regulation of DNA binding transcription factor activity
0.56	GO:0010469	regulation of receptor activity
0.56	GO:0001890	placenta development
0.53	GO:0045893	positive regulation of transcription, DNA-templated
0.52	GO:0009653	anatomical structure morphogenesis
0.36	GO:0060135	maternal process involved in female pregnancy
0.36	GO:0007605	sensory perception of sound

0.61	GO:0005109	frizzled binding
0.59	GO:0005125	cytokine activity
0.54	GO:0042803	protein homodimerization activity
0.35	GO:0008083	growth factor activity

0.73	GO:0005615	extracellular space
0.56	GO:0031012	extracellular matrix
0.55	GO:0009986	cell surface
0.30	GO:0016020	membrane

sp|Q00610|CLH1_HUMAN
Clathrin heavy chain 1
Search

CLTC

0.65	Clathrin heavy chain

0.82	GO:0048268	clathrin coat assembly
0.69	GO:0006886	intracellular protein transport
0.68	GO:0016192	vesicle-mediated transport
0.40	GO:1900126	negative regulation of hyaluronan biosynthetic process
0.38	GO:0033572	transferrin transport
0.38	GO:1903077	negative regulation of protein localization to plasma membrane
0.37	GO:0060236	regulation of mitotic spindle organization
0.37	GO:0006914	autophagy
0.37	GO:0043112	receptor metabolic process
0.37	GO:0016482	cytosolic transport

0.85	GO:0032051	clathrin light chain binding
0.61	GO:0005198	structural molecule activity
0.46	GO:0019901	protein kinase binding
0.40	GO:0097718	disordered domain specific binding
0.38	GO:1990381	ubiquitin-specific protease binding
0.38	GO:0050750	low-density lipoprotein particle receptor binding
0.36	GO:0003725	double-stranded RNA binding
0.35	GO:0004386	helicase activity
0.35	GO:1990763	arrestin family protein binding
0.35	GO:0030506	ankyrin binding

0.84	GO:0071439	clathrin complex
0.82	GO:0030130	clathrin coat of trans-Golgi network vesicle
0.81	GO:0030132	clathrin coat of coated pit
0.47	GO:0043209	myelin sheath
0.47	GO:0072686	mitotic spindle
0.46	GO:0005764	lysosome
0.45	GO:0005768	endosome
0.40	GO:0005739	mitochondrion
0.38	GO:0042470	melanosome
0.37	GO:0005876	spindle microtubule

sp|Q00613|HSF1_HUMAN
Heat shock factor protein 1
Search

HSF1

0.94	Heat shock transcription factor 1

0.58	GO:0072738	cellular response to diamide
0.58	GO:1900365	positive regulation of mRNA polyadenylation
0.58	GO:1903936	cellular response to sodium arsenite
0.56	GO:0043497	regulation of protein heterodimerization activity
0.56	GO:0071280	cellular response to copper ion
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:2001033	negative regulation of double-strand break repair via nonhomologous end joining
0.56	GO:0060136	embryonic process involved in female pregnancy
0.56	GO:1900034	regulation of cellular response to heat

0.63	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.58	GO:0061770	translation elongation factor binding
0.56	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding
0.55	GO:0051879	Hsp90 protein binding
0.55	GO:1990841	promoter-specific chromatin binding
0.54	GO:0043621	protein self-association
0.53	GO:0031490	chromatin DNA binding
0.51	GO:0019901	protein kinase binding
0.51	GO:0001012	RNA polymerase II regulatory region DNA binding

0.61	GO:0005634	nucleus
0.55	GO:0097431	mitotic spindle pole
0.51	GO:0048471	perinuclear region of cytoplasm
0.51	GO:0035770	ribonucleoprotein granule
0.51	GO:0000776	kinetochore
0.51	GO:0005813	centrosome
0.47	GO:0005829	cytosol
0.46	GO:0070013	intracellular organelle lumen
0.41	GO:0000791	euchromatin
0.41	GO:0000792	heterochromatin

sp|Q00653|NFKB2_HUMAN
Nuclear factor NF-kappa-B p100 subunit
Search

NFKB2

0.97	Nuclear factor kappa B subunit 2

0.61	GO:0002268	follicular dendritic cell differentiation
0.61	GO:0038061	NIK/NF-kappaB signaling
0.59	GO:0002467	germinal center formation
0.58	GO:0048536	spleen development
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.54	GO:0030198	extracellular matrix organization
0.53	GO:0051254	positive regulation of RNA metabolic process
0.53	GO:0010557	positive regulation of macromolecule biosynthetic process

0.61	GO:0003700	DNA binding transcription factor activity
0.56	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.54	GO:0000987	proximal promoter sequence-specific DNA binding
0.47	GO:0003682	chromatin binding
0.38	GO:0005515	protein binding
0.37	GO:0001158	enhancer sequence-specific DNA binding
0.35	GO:0003713	transcription coactivator activity
0.33	GO:0098772	molecular function regulator

0.63	GO:0033256	I-kappaB/NF-kappaB complex
0.61	GO:0005634	nucleus
0.51	GO:0005829	cytosol
0.36	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part
0.34	GO:0005739	mitochondrion

sp|Q00688|FKBP3_HUMAN
Peptidyl-prolyl cis-trans isomerase FKBP3
Search

FKBP3

0.54	Peptidyl-prolyl cis-trans isomerase FKBP3

0.67	GO:0061077	chaperone-mediated protein folding
0.67	GO:0000413	protein peptidyl-prolyl isomerization

0.73	GO:0005528	FK506 binding
0.67	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.51	GO:0005515	protein binding
0.46	GO:0004872	receptor activity
0.43	GO:0003723	RNA binding

0.58	GO:0005634	nucleus
0.44	GO:0005737	cytoplasm

0.67

GO:0003755

sp|Q00722|PLCB2_HUMAN
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2
Search

PLCB2

0.53	Phosphoinositide phospholipase C

0.72	GO:0016042	lipid catabolic process
0.62	GO:0035556	intracellular signal transduction
0.56	GO:0050913	sensory perception of bitter taste
0.49	GO:0007420	brain development
0.46	GO:0051726	regulation of cell cycle
0.41	GO:2000560	positive regulation of CD24 biosynthetic process
0.41	GO:2000438	negative regulation of monocyte extravasation
0.41	GO:0035723	interleukin-15-mediated signaling pathway
0.41	GO:0035722	interleukin-12-mediated signaling pathway
0.41	GO:2000344	positive regulation of acrosome reaction

0.81	GO:0004435	phosphatidylinositol phospholipase C activity
0.65	GO:0005509	calcium ion binding
0.63	GO:0004871	signal transducer activity
0.40	GO:0005521	lamin binding
0.40	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.39	GO:0005516	calmodulin binding
0.38	GO:0005096	GTPase activator activity
0.37	GO:0019899	enzyme binding

0.45	GO:0005622	intracellular
0.40	GO:0043227	membrane-bounded organelle
0.39	GO:0043209	myelin sheath
0.37	GO:0043233	organelle lumen
0.35	GO:0043228	non-membrane-bounded organelle

0.81	EC:3.1.4.11	GO:0004435
0.81	KEGG:R03435	GO:0004435

sp|Q00765|REEP5_HUMAN
Receptor expression-enhancing protein 5
Search

REEP5

0.71	Receptor expression-enhancing protein 5

0.34

GO:0050908

detection of light stimulus involved in visual perception

0.34

GO:0005515

protein binding

0.55	GO:0071782	endoplasmic reticulum tubular network
0.36	GO:0070062	extracellular exosome
0.34	GO:0001917	photoreceptor inner segment
0.30	GO:0031224	intrinsic component of membrane

sp|Q00796|DHSO_HUMAN
Sorbitol dehydrogenase
Search

SORD

0.60	Sorbitol dehydrogenase

0.61	GO:0046370	fructose biosynthetic process
0.61	GO:0006062	sorbitol catabolic process
0.60	GO:0051160	L-xylitol catabolic process
0.55	GO:0030317	flagellated sperm motility
0.53	GO:0055114	oxidation-reduction process
0.38	GO:0046686	response to cadmium ion
0.38	GO:0046688	response to copper ion
0.37	GO:0006970	response to osmotic stress
0.37	GO:0031667	response to nutrient levels
0.37	GO:0009725	response to hormone

0.62	GO:0008270	zinc ion binding
0.58	GO:0003939	L-iditol 2-dehydrogenase activity
0.50	GO:0042802	identical protein binding
0.48	GO:0051287	NAD binding
0.39	GO:0046526	D-xylulose reductase activity
0.34	GO:0030246	carbohydrate binding
0.33	GO:0050567	glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding

0.53	GO:0070062	extracellular exosome
0.53	GO:0031514	motile cilium
0.44	GO:0005739	mitochondrion
0.38	GO:0031967	organelle envelope
0.38	GO:0031090	organelle membrane
0.34	GO:0032991	macromolecular complex
0.34	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.58	EC:1.1.1.14	GO:0003939
0.39	KEGG:R01896	GO:0046526

sp|Q00839|HNRPU_HUMAN
Heterogeneous nuclear ribonucleoprotein U
Search

HNRNPU

0.97	Heterogeneous nuclear ribonucleoprotein U

0.60	GO:1990280	RNA localization to chromatin
0.59	GO:0070934	CRD-mediated mRNA stabilization
0.59	GO:1902889	protein localization to spindle microtubule
0.59	GO:1902425	positive regulation of attachment of mitotic spindle microtubules to kinetochore
0.58	GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter
0.58	GO:2000737	negative regulation of stem cell differentiation
0.57	GO:0032211	negative regulation of telomere maintenance via telomerase
0.57	GO:1901673	regulation of mitotic spindle assembly
0.57	GO:0051457	maintenance of protein location in nucleus
0.57	GO:0071385	cellular response to glucocorticoid stimulus

0.61	GO:0017130	poly(C) RNA binding
0.60	GO:0001097	TFIIH-class transcription factor binding
0.59	GO:0034046	poly(G) binding
0.58	GO:0099122	RNA polymerase II C-terminal domain binding
0.58	GO:0070034	telomerase RNA binding
0.57	GO:1990841	promoter-specific chromatin binding
0.56	GO:0008143	poly(A) binding
0.56	GO:0036002	pre-mRNA binding
0.55	GO:0031490	chromatin DNA binding
0.55	GO:0003730	mRNA 3'-UTR binding

0.61	GO:0005634	nucleus
0.61	GO:0098577	inactive sex chromosome
0.59	GO:0070937	CRD-mediated mRNA stability complex
0.58	GO:1990498	mitotic spindle microtubule
0.57	GO:0019013	viral nucleocapsid
0.56	GO:1990023	mitotic spindle midzone
0.55	GO:0030496	midbody
0.55	GO:0030529	intracellular ribonucleoprotein complex
0.53	GO:0000776	kinetochore
0.53	GO:0005813	centrosome

sp|Q00872|MYPC1_HUMAN
Myosin-binding protein C, slow-type
Search

MYBPC1

0.49	Myosin-binding protein C, slow-type

0.75	GO:1903955	positive regulation of protein targeting to mitochondrion
0.72	GO:0006936	muscle contraction
0.67	GO:0071688	striated muscle myosin thick filament assembly
0.64	GO:0045214	sarcomere organization
0.57	GO:0007015	actin filament organization
0.55	GO:0033275	actin-myosin filament sliding
0.50	GO:0007155	cell adhesion
0.43	GO:0008654	phospholipid biosynthetic process

0.67	GO:0097493	structural molecule activity conferring elasticity
0.67	GO:0051371	muscle alpha-actinin binding
0.65	GO:0008307	structural constituent of muscle
0.60	GO:0005200	structural constituent of cytoskeleton
0.59	GO:0051015	actin filament binding
0.54	GO:0031432	titin binding
0.45	GO:0017022	myosin binding
0.44	GO:0016780	phosphotransferase activity, for other substituted phosphate groups

0.66	GO:0005859	muscle myosin complex
0.65	GO:0031430	M band
0.63	GO:0030018	Z disc
0.59	GO:0032982	myosin filament
0.45	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.44

EC:2.7.8

GO:0016780

sp|Q00887|PSG9_HUMAN
Pregnancy-specific beta-1-glycoprotein 9
Search

0.93	Pregnancy specific beta-1-glycoprotein 4

0.79	GO:0007565	female pregnancy
0.41	GO:0006952	defense response
0.40	GO:0043317	regulation of cytotoxic T cell degranulation
0.40	GO:0002859	negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
0.39	GO:0001915	negative regulation of T cell mediated cytotoxicity
0.39	GO:0043301	negative regulation of leukocyte degranulation
0.39	GO:0050860	negative regulation of T cell receptor signaling pathway
0.39	GO:0016477	cell migration
0.39	GO:0090505	epiboly involved in wound healing
0.38	GO:0050868	negative regulation of T cell activation

0.39	GO:0031005	filamin binding
0.38	GO:1990782	protein tyrosine kinase binding
0.38	GO:0019903	protein phosphatase binding
0.37	GO:0042803	protein homodimerization activity
0.37	GO:0003779	actin binding

0.50	GO:0005576	extracellular region
0.41	GO:0031982	vesicle
0.39	GO:0042101	T cell receptor complex
0.37	GO:0005911	cell-cell junction
0.37	GO:0009986	cell surface
0.35	GO:0098805	whole membrane
0.35	GO:0098588	bounding membrane of organelle
0.34	GO:0012505	endomembrane system
0.33	GO:0044446	intracellular organelle part
0.33	GO:0044444	cytoplasmic part

sp|Q00888|PSG4_HUMAN
Pregnancy-specific beta-1-glycoprotein 4
Search

PSG3

0.88	Pregnancy-specific beta-1-glycoprotein 8

0.81	GO:0007565	female pregnancy
0.39	GO:0043312	neutrophil degranulation
0.38	GO:0050900	leukocyte migration
0.38	GO:0006952	defense response

0.37

GO:0005515

protein binding

0.44	GO:0005576	extracellular region
0.39	GO:0035579	specific granule membrane
0.34	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

sp|Q00889|PSG6_HUMAN
Pregnancy-specific beta-1-glycoprotein 6
Search

0.93	Pregnancy-specific beta-1-glycoprotein 6

0.80	GO:0007565	female pregnancy
0.44	GO:0016477	cell migration
0.41	GO:0006952	defense response
0.41	GO:0002376	immune system process
0.40	GO:0043317	regulation of cytotoxic T cell degranulation
0.39	GO:0002859	negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
0.39	GO:0001915	negative regulation of T cell mediated cytotoxicity
0.39	GO:0043301	negative regulation of leukocyte degranulation
0.38	GO:0050860	negative regulation of T cell receptor signaling pathway
0.38	GO:0090505	epiboly involved in wound healing

0.39

GO:0005515

protein binding

0.51	GO:0005576	extracellular region
0.41	GO:0031982	vesicle
0.38	GO:0042101	T cell receptor complex
0.37	GO:0005911	cell-cell junction
0.37	GO:0009986	cell surface
0.35	GO:0098805	whole membrane
0.35	GO:0098588	bounding membrane of organelle
0.34	GO:0012505	endomembrane system
0.33	GO:0044446	intracellular organelle part
0.33	GO:0044444	cytoplasmic part

sp|Q008S8|ECT2L_HUMAN
Epithelial cell-transforming sequence 2 oncogene-like
Search

ECT2L

0.97	Epithelial cell transforming 2 like

0.78	GO:0035023	regulation of Rho protein signal transduction
0.66	GO:0065009	regulation of molecular function

0.78

GO:0005089

Rho guanyl-nucleotide exchange factor activity

sp|Q00973|B4GN1_HUMAN
Beta-1,4 N-acetylgalactosaminyltransferase 1
Search

B4GALNT1

0.85	UDP-N-acetyl-alpha-D-galactosamine:(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase variant (Fragment)

0.72	GO:0030259	lipid glycosylation
0.61	GO:0001574	ganglioside biosynthetic process
0.57	GO:0019915	lipid storage
0.55	GO:0007283	spermatogenesis
0.43	GO:0022408	negative regulation of cell-cell adhesion
0.42	GO:0006047	UDP-N-acetylglucosamine metabolic process
0.42	GO:0019276	UDP-N-acetylgalactosamine metabolic process
0.41	GO:0043413	macromolecule glycosylation
0.40	GO:0009101	glycoprotein biosynthetic process
0.37	GO:0036211	protein modification process

0.66	GO:0016758	transferase activity, transferring hexosyl groups
0.55	GO:0008194	UDP-glycosyltransferase activity

0.76	GO:0030173	integral component of Golgi membrane
0.35	GO:0005886	plasma membrane

0.66

GO:0016758

sp|Q00975|CAC1B_HUMAN
Voltage-dependent N-type calcium channel subunit alpha-1B
Search

CACNA1B

0.87	Voltage-dependent N-type calcium channel subunit alpha

0.77	GO:0034765	regulation of ion transmembrane transport
0.77	GO:0070588	calcium ion transmembrane transport
0.53	GO:0048265	response to pain
0.52	GO:0007626	locomotory behavior
0.51	GO:0007269	neurotransmitter secretion
0.51	GO:0008016	regulation of heart contraction
0.51	GO:0008217	regulation of blood pressure
0.51	GO:0051924	regulation of calcium ion transport
0.48	GO:0051899	membrane depolarization
0.47	GO:0001508	action potential

0.82	GO:0005245	voltage-gated calcium channel activity
0.58	GO:0005509	calcium ion binding
0.51	GO:0008022	protein C-terminus binding
0.36	GO:0051721	protein phosphatase 2A binding
0.35	GO:0030554	adenyl nucleotide binding
0.35	GO:0097367	carbohydrate derivative binding
0.35	GO:0008144	drug binding
0.35	GO:0035639	purine ribonucleoside triphosphate binding

0.81	GO:0005891	voltage-gated calcium channel complex
0.51	GO:0043025	neuronal cell body
0.51	GO:0030425	dendrite
0.50	GO:0098793	presynapse
0.38	GO:0044306	neuron projection terminus
0.35	GO:0009986	cell surface
0.33	GO:0043234	protein complex

sp|Q00978|IRF9_HUMAN
Interferon regulatory factor 9
Search

IRF9

0.97	LOW QUALITY PROTEIN: interferon regulatory factor 9

0.57	GO:0006351	transcription, DNA-templated
0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.45	GO:0071346	cellular response to interferon-gamma
0.44	GO:0044130	negative regulation of growth of symbiont in host
0.44	GO:0042832	defense response to protozoan
0.44	GO:0032735	positive regulation of interleukin-12 production
0.44	GO:0030099	myeloid cell differentiation
0.43	GO:0032729	positive regulation of interferon-gamma production

0.75	GO:0044212	transcription regulatory region DNA binding
0.60	GO:0003700	DNA binding transcription factor activity
0.41	GO:1990837	sequence-specific double-stranded DNA binding
0.36	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.52	GO:0005829	cytosol
0.40	GO:0043233	organelle lumen
0.38	GO:0044446	intracellular organelle part

sp|Q00987|MDM2_HUMAN
E3 ubiquitin-protein ligase Mdm2
Search

MDM2

0.92	E3 ubiquitin-protein ligase Mdm2 isoform A

0.85	GO:0071157	negative regulation of cell cycle arrest
0.76	GO:0043066	negative regulation of apoptotic process
0.76	GO:0000122	negative regulation of transcription by RNA polymerase II
0.71	GO:0016567	protein ubiquitination
0.57	GO:0072717	cellular response to actinomycin D
0.55	GO:1990000	amyloid fibril formation
0.55	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
0.55	GO:0007089	traversing start control point of mitotic cell cycle
0.55	GO:0003283	atrial septum development
0.55	GO:0003181	atrioventricular valve morphogenesis

0.57	GO:0061663	NEDD8 ligase activity
0.55	GO:0016874	ligase activity
0.54	GO:0097110	scaffold protein binding
0.54	GO:0097718	disordered domain specific binding
0.53	GO:0002039	p53 binding
0.53	GO:0047485	protein N-terminus binding
0.52	GO:0008097	5S rRNA binding
0.52	GO:0046872	metal ion binding
0.50	GO:0031625	ubiquitin protein ligase binding
0.50	GO:0043021	ribonucleoprotein complex binding

0.60	GO:0005634	nucleus
0.48	GO:0070013	intracellular organelle lumen
0.44	GO:0043232	intracellular non-membrane-bounded organelle
0.43	GO:0044446	intracellular organelle part
0.42	GO:0043234	protein complex
0.39	GO:0005737	cytoplasm
0.39	GO:0045202	synapse
0.35	GO:0005886	plasma membrane
0.35	GO:0012506	vesicle membrane
0.35	GO:0097708	intracellular vesicle

0.55

GO:0016874

sp|Q00994|BEX3_HUMAN
Protein BEX3
Search

0.97	Brain expressed X-linked 3

0.61	GO:1904428	negative regulation of tubulin deacetylation
0.53	GO:0030334	regulation of cell migration
0.52	GO:0042127	regulation of cell proliferation
0.50	GO:0007059	chromosome segregation
0.49	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors
0.46	GO:0051091	positive regulation of DNA binding transcription factor activity
0.44	GO:0045944	positive regulation of transcription by RNA polymerase II
0.41	GO:0042981	regulation of apoptotic process
0.41	GO:0051726	regulation of cell cycle

0.65	GO:0042802	identical protein binding
0.57	GO:0043014	alpha-tubulin binding
0.56	GO:0042826	histone deacetylase binding
0.50	GO:0005123	death receptor binding
0.48	GO:0001102	RNA polymerase II activating transcription factor binding

0.61	GO:0005829	cytosol
0.53	GO:0000922	spindle pole
0.50	GO:0005874	microtubule
0.45	GO:0005634	nucleus
0.44	GO:0005667	transcription factor complex

sp|Q00G26|PLIN5_HUMAN
Perilipin-5
Search

PLIN5

0.76

Perilipin

0.87	GO:0010897	negative regulation of triglyceride catabolic process
0.87	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway
0.86	GO:0031999	negative regulation of fatty acid beta-oxidation
0.86	GO:0010890	positive regulation of sequestering of triglyceride
0.86	GO:0032000	positive regulation of fatty acid beta-oxidation
0.86	GO:0010867	positive regulation of triglyceride biosynthetic process
0.86	GO:0060192	negative regulation of lipase activity
0.85	GO:0034389	lipid particle organization
0.85	GO:2000378	negative regulation of reactive oxygen species metabolic process
0.80	GO:0019915	lipid storage

0.86	GO:0035473	lipase binding
0.71	GO:0042802	identical protein binding
0.46	GO:0045296	cadherin binding

0.82	GO:0005811	lipid droplet
0.68	GO:0005829	cytosol
0.45	GO:0005739	mitochondrion
0.36	GO:0010008	endosome membrane

sp|Q00LT1|PRCD_HUMAN
Progressive rod-cone degeneration protein
Search

PRCD

0.94	Progressive rod-cone degeneration protein homolog

0.78	GO:0007601	visual perception
0.56	GO:0050896	response to stimulus

0.85	GO:0001750	photoreceptor outer segment
0.71	GO:0005794	Golgi apparatus
0.70	GO:0005783	endoplasmic reticulum
0.66	GO:0005576	extracellular region

sp|Q01064|PDE1B_HUMAN
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B
Search

PDE1B

0.54	Phosphodiesterase

0.60	GO:0007165	signal transduction
0.57	GO:0046069	cGMP catabolic process
0.56	GO:0036006	cellular response to macrophage colony-stimulating factor stimulus
0.56	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus
0.56	GO:0042053	regulation of dopamine metabolic process
0.55	GO:0001975	response to amphetamine
0.55	GO:0042428	serotonin metabolic process
0.55	GO:1903131	mononuclear cell differentiation
0.54	GO:0008542	visual learning
0.54	GO:0006198	cAMP catabolic process

0.79	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.53	GO:0046872	metal ion binding
0.40	GO:0005516	calmodulin binding
0.36	GO:0030553	cGMP binding

0.40	GO:0043025	neuronal cell body
0.35	GO:0005829	cytosol
0.33	GO:0005929	cilium
0.33	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.79

EC:3.1.4.17

GO:0004114

sp|Q01081|U2AF1_HUMAN
Splicing factor U2AF 35 kDa subunit
Search

U2AF1

0.89	U2 small nuclear RNA auxiliary factor small subunit

0.75

GO:0000398

mRNA splicing, via spliceosome

0.59	GO:0003723	RNA binding
0.54	GO:0046872	metal ion binding
0.47	GO:0050733	RS domain binding

0.84	GO:0089701	U2AF
0.48	GO:0005681	spliceosomal complex
0.43	GO:0016607	nuclear speck
0.30	GO:0016021	integral component of membrane

sp|Q01082|SPTB2_HUMAN
Spectrin beta chain, non-erythrocytic 1
Search

SPTBN1

0.73	Spectrin beta chain

0.81	GO:0051693	actin filament capping
0.71	GO:0007010	cytoskeleton organization
0.52	GO:1900042	positive regulation of interleukin-2 secretion
0.51	GO:0007184	SMAD protein import into nucleus
0.51	GO:0007182	common-partner SMAD protein phosphorylation
0.50	GO:1903078	positive regulation of protein localization to plasma membrane
0.50	GO:0043001	Golgi to plasma membrane protein transport
0.48	GO:0007009	plasma membrane organization
0.48	GO:0000281	mitotic cytokinesis
0.46	GO:0071709	membrane assembly

0.77	GO:0005200	structural constituent of cytoskeleton
0.74	GO:0003779	actin binding
0.73	GO:0005543	phospholipid binding
0.51	GO:0030506	ankyrin binding
0.48	GO:0045296	cadherin binding
0.46	GO:0051020	GTPase binding
0.34	GO:0032403	protein complex binding
0.33	GO:0005516	calmodulin binding
0.32	GO:0003723	RNA binding
0.32	GO:0098772	molecular function regulator

0.85	GO:0008091	spectrin
0.51	GO:0032437	cuticular plate
0.50	GO:0030673	axolemma
0.49	GO:0031430	M band
0.48	GO:0014069	postsynaptic density
0.45	GO:0005730	nucleolus
0.34	GO:0070062	extracellular exosome
0.33	GO:0043234	protein complex
0.33	GO:0098836	cytoskeleton of dendritic spine
0.33	GO:0014731	spectrin-associated cytoskeleton

sp|Q01085|TIAR_HUMAN
Nucleolysin TIAR
Search

TIAL1

0.91	TIA1 cytotoxic granule associated RNA binding protein like 1

0.55	GO:0017145	stem cell division
0.52	GO:0007281	germ cell development
0.52	GO:0008284	positive regulation of cell proliferation
0.36	GO:0006915	apoptotic process
0.35	GO:0008543	fibroblast growth factor receptor signaling pathway
0.34	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway
0.34	GO:0006952	defense response
0.34	GO:0006357	regulation of transcription by RNA polymerase II

0.59	GO:0003723	RNA binding
0.53	GO:0003677	DNA binding
0.35	GO:0001965	G-protein alpha-subunit binding

0.53	GO:0010494	cytoplasmic stress granule
0.44	GO:0005634	nucleus
0.36	GO:0070062	extracellular exosome
0.34	GO:0005764	lysosome
0.33	GO:0043233	organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|Q01094|E2F1_HUMAN
Transcription factor E2F1
Search

E2F1

0.90	E2F transcription factor 1

0.74	GO:0070345	negative regulation of fat cell proliferation
0.71	GO:1990086	lens fiber cell apoptotic process
0.68	GO:0043276	anoikis
0.67	GO:0071930	negative regulation of transcription involved in G1/S transition of mitotic cell cycle
0.66	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator
0.65	GO:0045599	negative regulation of fat cell differentiation
0.64	GO:0048255	mRNA stabilization
0.64	GO:0048146	positive regulation of fibroblast proliferation
0.64	GO:0043065	positive regulation of apoptotic process
0.64	GO:0043392	negative regulation of DNA binding

0.68	GO:0046983	protein dimerization activity
0.68	GO:0001047	core promoter binding
0.61	GO:0003700	DNA binding transcription factor activity
0.58	GO:0008134	transcription factor binding
0.55	GO:0043565	sequence-specific DNA binding
0.50	GO:0001012	RNA polymerase II regulatory region DNA binding
0.47	GO:0003690	double-stranded DNA binding
0.37	GO:0019901	protein kinase binding

0.75	GO:0005667	transcription factor complex
0.61	GO:0005634	nucleus
0.59	GO:0005813	centrosome
0.56	GO:0000785	chromatin
0.53	GO:0031974	membrane-enclosed lumen
0.42	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q01101|INSM1_HUMAN
Insulinoma-associated protein 1
Search

0.85	INSM transcriptional repressor 1

0.62	GO:0060290	transdifferentiation
0.60	GO:0061104	adrenal chromaffin cell differentiation
0.60	GO:0003358	noradrenergic neuron development
0.59	GO:0003310	pancreatic A cell differentiation
0.58	GO:0071158	positive regulation of cell cycle arrest
0.58	GO:0042421	norepinephrine biosynthetic process
0.58	GO:0061549	sympathetic ganglion development
0.58	GO:0003309	type B pancreatic cell differentiation
0.56	GO:2000179	positive regulation of neural precursor cell proliferation
0.56	GO:0002068	glandular epithelial cell development

0.57	GO:0031490	chromatin DNA binding
0.57	GO:0001047	core promoter binding
0.56	GO:0042826	histone deacetylase binding
0.56	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.55	GO:0030332	cyclin binding
0.54	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.38	GO:0046872	metal ion binding
0.36	GO:0001085	RNA polymerase II transcription factor binding
0.33	GO:0003714	transcription corepressor activity
0.33	GO:0017048	Rho GTPase binding

0.56	GO:0017053	transcriptional repressor complex
0.46	GO:0005634	nucleus
0.36	GO:0031974	membrane-enclosed lumen
0.35	GO:0005829	cytosol
0.34	GO:0044446	intracellular organelle part

sp|Q01105|SET_HUMAN
Protein SET
Search

SET

0.92	SET nuclear proto-oncogene

0.79	GO:0006334	nucleosome assembly
0.42	GO:0048884	neuromast development
0.39	GO:0043524	negative regulation of neuron apoptotic process
0.37	GO:0045892	negative regulation of transcription, DNA-templated
0.36	GO:0045446	endothelial cell differentiation
0.35	GO:0045944	positive regulation of transcription by RNA polymerase II
0.35	GO:0006468	protein phosphorylation
0.35	GO:0035067	negative regulation of histone acetylation
0.35	GO:0031498	chromatin disassembly
0.35	GO:0032986	protein-DNA complex disassembly

0.38	GO:0017049	GTP-Rho binding
0.36	GO:0004674	protein serine/threonine kinase activity
0.35	GO:0003682	chromatin binding
0.35	GO:0004864	protein phosphatase inhibitor activity
0.34	GO:0042393	histone binding
0.34	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0003677	DNA binding

0.61	GO:0005634	nucleus
0.41	GO:0005811	lipid droplet
0.38	GO:0031974	membrane-enclosed lumen
0.38	GO:0048471	perinuclear region of cytoplasm
0.36	GO:0005783	endoplasmic reticulum
0.36	GO:0044446	intracellular organelle part
0.35	GO:0005829	cytosol
0.35	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.36

GO:0004674

sp|Q01113|IL9R_HUMAN
Interleukin-9 receptor
Search

IL9R

0.97	Interleukin-9 receptor

0.78	GO:0019221	cytokine-mediated signaling pathway
0.64	GO:1903955	positive regulation of protein targeting to mitochondrion
0.50	GO:0071355	cellular response to interleukin-9
0.42	GO:0030307	positive regulation of cell growth
0.40	GO:0008283	cell proliferation
0.34	GO:0006351	transcription, DNA-templated

0.80	GO:0004896	cytokine receptor activity
0.46	GO:0019983	interleukin-9 binding

0.38	GO:0005576	extracellular region
0.37	GO:0005887	integral component of plasma membrane

sp|Q01118|SCN7A_HUMAN
Sodium channel protein type 7 subunit alpha
Search

SCN7A

0.46	Sodium channel protein type 7 subunit alpha

0.77	GO:0035725	sodium ion transmembrane transport
0.76	GO:0034765	regulation of ion transmembrane transport
0.72	GO:0006936	muscle contraction
0.63	GO:0048266	behavioral response to pain
0.63	GO:0055078	sodium ion homeostasis
0.58	GO:0006954	inflammatory response
0.57	GO:0019228	neuronal action potential
0.57	GO:0086010	membrane depolarization during action potential
0.49	GO:0019233	sensory perception of pain
0.46	GO:0009791	post-embryonic development

0.84	GO:0005248	voltage-gated sodium channel activity
0.73	GO:0022832	voltage-gated channel activity
0.71	GO:0022839	ion gated channel activity
0.71	GO:0008381	mechanosensitive ion channel activity
0.36	GO:0005509	calcium ion binding
0.36	GO:0031402	sodium ion binding

0.83	GO:0001518	voltage-gated sodium channel complex
0.64	GO:0097386	glial cell projection
0.32	GO:0005737	cytoplasm

sp|Q01130|SRSF2_HUMAN
Serine/arginine-rich splicing factor 2
Search

SRSF2

0.93	Serine and arginine rich splicing factor 2

0.77	GO:0043484	regulation of RNA splicing
0.46	GO:0050684	regulation of mRNA processing
0.41	GO:0033197	response to vitamin E
0.40	GO:0008380	RNA splicing
0.40	GO:0006397	mRNA processing
0.38	GO:0000278	mitotic cell cycle
0.35	GO:0006369	termination of RNA polymerase II transcription
0.35	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.34	GO:0031123	RNA 3'-end processing
0.34	GO:0051028	mRNA transport

0.59	GO:0003723	RNA binding
0.40	GO:0005080	protein kinase C binding
0.35	GO:0003714	transcription corepressor activity
0.33	GO:0004623	phospholipase A2 activity

0.49	GO:0016607	nuclear speck
0.46	GO:0005681	spliceosomal complex
0.45	GO:0005829	cytosol
0.41	GO:0035061	interchromatin granule
0.37	GO:0016605	PML body
0.36	GO:0070062	extracellular exosome
0.33	GO:0019013	viral nucleocapsid
0.30	GO:0016020	membrane

0.33

EC:3.1.1.4

GO:0004623

sp|Q01151|CD83_HUMAN
CD83 antigen
Search

sp|Q01167|FOXK2_HUMAN
Forkhead box protein K2
Search

FOXK2

0.96	LOW QUALITY PROTEIN: forkhead box protein K2

0.57	GO:0006355	regulation of transcription, DNA-templated
0.49	GO:0006366	transcription by RNA polymerase II
0.48	GO:1903508	positive regulation of nucleic acid-templated transcription
0.47	GO:0010628	positive regulation of gene expression
0.43	GO:0030154	cell differentiation
0.43	GO:0009653	anatomical structure morphogenesis
0.35	GO:0016579	protein deubiquitination

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.50	GO:0001012	RNA polymerase II regulatory region DNA binding
0.47	GO:0003690	double-stranded DNA binding
0.45	GO:0000287	magnesium ion binding
0.34	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.32	GO:0044599	AP-5 adaptor complex
0.30	GO:0031224	intrinsic component of membrane

sp|Q01196|RUNX1_HUMAN
Runt-related transcription factor 1
Search

RUNX1

0.89	Runt-related transcription factor

0.69	GO:0045893	positive regulation of transcription, DNA-templated
0.61	GO:0030854	positive regulation of granulocyte differentiation
0.59	GO:0032743	positive regulation of interleukin-2 production
0.56	GO:0030097	hemopoiesis
0.55	GO:0006351	transcription, DNA-templated
0.51	GO:0002062	chondrocyte differentiation
0.51	GO:0006357	regulation of transcription by RNA polymerase II
0.47	GO:0001503	ossification
0.45	GO:0030182	neuron differentiation
0.41	GO:0009953	dorsal/ventral pattern formation

0.60	GO:0003700	DNA binding transcription factor activity
0.56	GO:0001047	core promoter binding
0.54	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0042809	vitamin D receptor binding
0.39	GO:0046982	protein heterodimerization activity
0.38	GO:0005509	calcium ion binding

0.60	GO:0005634	nucleus
0.49	GO:0005829	cytosol
0.49	GO:0070013	intracellular organelle lumen
0.44	GO:0044446	intracellular organelle part
0.38	GO:0005604	basement membrane
0.34	GO:0043234	protein complex
0.30	GO:0016020	membrane

sp|Q01201|RELB_HUMAN
Transcription factor RelB
Search

RELB

0.92	V-rel avian reticuloendotheliosis viral oncogene homolog

0.64	GO:0007249	I-kappaB kinase/NF-kappaB signaling
0.60	GO:0048518	positive regulation of biological process
0.60	GO:0006357	regulation of transcription by RNA polymerase II
0.54	GO:0051090	regulation of DNA binding transcription factor activity
0.53	GO:0038061	NIK/NF-kappaB signaling
0.52	GO:0032688	negative regulation of interferon-beta production
0.50	GO:0044093	positive regulation of molecular function
0.49	GO:0006954	inflammatory response
0.49	GO:0034097	response to cytokine
0.48	GO:0045087	innate immune response

0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0003677	DNA binding
0.51	GO:0001067	regulatory region nucleic acid binding
0.48	GO:0003682	chromatin binding
0.43	GO:0019901	protein kinase binding
0.42	GO:0042802	identical protein binding
0.38	GO:0003714	transcription corepressor activity
0.36	GO:0008047	enzyme activator activity
0.35	GO:0071532	ankyrin repeat binding
0.35	GO:0046982	protein heterodimerization activity

0.61	GO:0005634	nucleus
0.58	GO:0071159	NF-kappaB complex
0.53	GO:0033256	I-kappaB/NF-kappaB complex
0.49	GO:0005737	cytoplasm
0.42	GO:0005813	centrosome
0.42	GO:0070013	intracellular organelle lumen
0.37	GO:0042627	chylomicron
0.35	GO:0005667	transcription factor complex
0.33	GO:0000785	chromatin
0.30	GO:0016020	membrane

sp|Q01344|IL5RA_HUMAN
Interleukin-5 receptor subunit alpha
Search

IL5RA

0.97	Interleukin-5 receptor subunit alpha

0.78	GO:0019221	cytokine-mediated signaling pathway
0.66	GO:0032674	regulation of interleukin-5 production
0.66	GO:0002437	inflammatory response to antigenic stimulus
0.37	GO:0008283	cell proliferation
0.37	GO:0000165	MAPK cascade
0.36	GO:0018108	peptidyl-tyrosine phosphorylation
0.35	GO:0065009	regulation of molecular function

0.80	GO:0004896	cytokine receptor activity
0.37	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.36	GO:0004713	protein tyrosine kinase activity

0.36	GO:0005615	extracellular space
0.34	GO:0005886	plasma membrane
0.32	GO:0005622	intracellular
0.32	GO:0043235	receptor complex
0.30	GO:0016021	integral component of membrane

0.36

GO:0004713

sp|Q01362|FCERB_HUMAN
High affinity immunoglobulin epsilon receptor subunit beta
Search

MS4A2

0.97	Membrane spanning 4-domains A2

0.86	GO:0038095	Fc-epsilon receptor signaling pathway
0.80	GO:0006954	inflammatory response
0.69	GO:0006955	immune response

0.85

GO:0019863

IgE binding

0.87	GO:0032997	Fc receptor complex
0.76	GO:0009897	external side of plasma membrane
0.67	GO:0005887	integral component of plasma membrane

sp|Q01415|GALK2_HUMAN
N-acetylgalactosamine kinase
Search

GALK2

0.93	N-acetylgalactosamine kinase

0.75	GO:0006012	galactose metabolic process
0.73	GO:0046835	carbohydrate phosphorylation

0.80	GO:0004335	galactokinase activity
0.77	GO:0005534	galactose binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0033858	N-acetylgalactosamine kinase activity

0.48

GO:0005737

cytoplasm

0.80	EC:2.7.1.6	GO:0004335
0.80	KEGG:R01092	GO:0004335

sp|Q01432|AMPD3_HUMAN
AMP deaminase 3
Search

AMPD3

0.74	AMP deaminase

0.79	GO:0032264	IMP salvage
0.56	GO:0097009	energy homeostasis
0.54	GO:0034101	erythrocyte homeostasis
0.51	GO:0046039	GTP metabolic process
0.50	GO:0046033	AMP metabolic process
0.48	GO:0046031	ADP metabolic process
0.44	GO:0046034	ATP metabolic process
0.37	GO:0009169	purine ribonucleoside monophosphate catabolic process
0.36	GO:0009154	purine ribonucleotide catabolic process
0.35	GO:0043312	neutrophil degranulation

0.84	GO:0003876	AMP deaminase activity
0.51	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.36	GO:1904813	ficolin-1-rich granule lumen
0.35	GO:0034774	secretory granule lumen
0.34	GO:0005829	cytosol
0.33	GO:0005576	extracellular region

0.84

EC:3.5.4.6

GO:0003876

sp|Q01433|AMPD2_HUMAN
AMP deaminase 2
Search

AMPD2

0.74	AMP deaminase

0.78	GO:0032264	IMP salvage
0.55	GO:0097009	energy homeostasis
0.50	GO:0052652	cyclic purine nucleotide metabolic process
0.37	GO:0072015	glomerular visceral epithelial cell development
0.37	GO:0042632	cholesterol homeostasis
0.36	GO:0046039	GTP metabolic process
0.35	GO:0046033	AMP metabolic process
0.34	GO:0046034	ATP metabolic process

0.82	GO:0003876	AMP deaminase activity
0.51	GO:0046872	metal ion binding
0.33	GO:0005515	protein binding

0.47

GO:0005829

cytosol

0.82

EC:3.5.4.6

GO:0003876

sp|Q01449|MLRA_HUMAN
Myosin regulatory light chain 2, atrial isoform
Search

MYL7

0.89	Myosin light chain, phosphorylatable, fast skeletal muscle a

0.48	GO:0055003	cardiac myofibril assembly
0.46	GO:0060047	heart contraction
0.46	GO:0055014	atrial cardiac muscle cell development
0.46	GO:0008016	regulation of heart contraction
0.45	GO:0055015	ventricular cardiac muscle cell development
0.45	GO:0060038	cardiac muscle cell proliferation
0.44	GO:1903524	positive regulation of blood circulation
0.44	GO:0045214	sarcomere organization
0.42	GO:0007517	muscle organ development
0.40	GO:0042694	muscle cell fate specification

0.69	GO:0005509	calcium ion binding
0.40	GO:0008307	structural constituent of muscle
0.39	GO:0003785	actin monomer binding

0.52	GO:0031672	A band
0.52	GO:0043197	dendritic spine
0.41	GO:0015629	actin cytoskeleton
0.40	GO:0097512	cardiac myofibril
0.37	GO:0044430	cytoskeletal part
0.35	GO:0043234	protein complex
0.34	GO:0036379	myofilament
0.34	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q01453|PMP22_HUMAN
Peripheral myelin protein 22
Search

PMP22

0.97	Peripheral myelin protein 22

0.63	GO:0032060	bleb assembly
0.56	GO:0008219	cell death
0.46	GO:0016049	cell growth
0.42	GO:0042127	regulation of cell proliferation
0.42	GO:0045595	regulation of cell differentiation
0.42	GO:2000026	regulation of multicellular organismal development
0.41	GO:0003093	regulation of glomerular filtration
0.41	GO:0001913	T cell mediated cytotoxicity
0.41	GO:0042552	myelination
0.41	GO:0007050	cell cycle arrest

0.39	GO:0005178	integrin binding
0.38	GO:0019901	protein kinase binding

0.44	GO:0005886	plasma membrane
0.41	GO:0043218	compact myelin
0.39	GO:0005923	bicellular tight junction
0.39	GO:0045121	membrane raft
0.39	GO:0045177	apical part of cell
0.38	GO:0009986	cell surface
0.38	GO:0031410	cytoplasmic vesicle
0.38	GO:0005794	Golgi apparatus
0.37	GO:0005829	cytosol
0.34	GO:0098588	bounding membrane of organelle

sp|Q01459|DIAC_HUMAN
Di-N-acetylchitobiase
Search

CTBS

0.84	Di-N-acetylchitobiase

0.60	GO:0005975	carbohydrate metabolic process
0.49	GO:0006032	chitin catabolic process
0.35	GO:0006869	lipid transport
0.33	GO:0007186	G-protein coupled receptor signaling pathway

0.76	GO:0008061	chitin binding
0.65	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.35	GO:0005319	lipid transporter activity
0.33	GO:0004871	signal transducer activity

0.43	GO:0005576	extracellular region
0.38	GO:0005764	lysosome
0.36	GO:0031982	vesicle
0.34	GO:1905360	GTPase complex
0.34	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.33	GO:0098797	plasma membrane protein complex
0.30	GO:0016021	integral component of membrane

0.65

GO:0004553

sp|Q01469|FABP5_HUMAN
Fatty acid-binding protein, epidermal
Search

FABP5

0.92	Fatty acid-binding protein, epidermal

0.48	GO:0006656	phosphatidylcholine biosynthetic process
0.47	GO:0015758	glucose transport
0.45	GO:0061024	membrane organization
0.43	GO:0006006	glucose metabolic process
0.43	GO:0050727	regulation of inflammatory response
0.41	GO:0007616	long-term memory
0.36	GO:0032502	developmental process
0.36	GO:0071285	cellular response to lithium ion
0.36	GO:0043312	neutrophil degranulation
0.36	GO:0019433	triglyceride catabolic process

0.72	GO:0008289	lipid binding
0.42	GO:0033293	monocarboxylic acid binding
0.34	GO:0015349	thyroid hormone transmembrane transporter activity
0.33	GO:0005515	protein binding

0.51	GO:0043209	myelin sheath
0.37	GO:0070062	extracellular exosome
0.36	GO:0035578	azurophil granule lumen
0.36	GO:0005654	nucleoplasm
0.35	GO:0030667	secretory granule membrane
0.35	GO:0005829	cytosol
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q01484|ANK2_HUMAN
Ankyrin-2
Search

ANK2

0.77

Ankyrin-2

0.65	GO:0098910	regulation of atrial cardiac muscle cell action potential
0.63	GO:0098907	regulation of SA node cell action potential
0.62	GO:0010881	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
0.62	GO:0086070	SA node cell to atrial cardiac muscle cell communication
0.62	GO:0086014	atrial cardiac muscle cell action potential
0.61	GO:0086005	ventricular cardiac muscle cell action potential
0.60	GO:0060307	regulation of ventricular cardiac muscle cell membrane repolarization
0.60	GO:0003283	atrial septum development
0.60	GO:0086091	regulation of heart rate by cardiac conduction
0.57	GO:0072659	protein localization to plasma membrane

0.61	GO:0030507	spectrin binding
0.59	GO:0044325	ion channel binding
0.55	GO:0019901	protein kinase binding
0.47	GO:0051117	ATPase binding
0.46	GO:0015459	potassium channel regulator activity
0.45	GO:0030674	protein binding, bridging
0.45	GO:0005200	structural constituent of cytoskeleton
0.33	GO:0005102	receptor binding
0.32	GO:0070001	aspartic-type peptidase activity
0.32	GO:0004175	endopeptidase activity

0.57	GO:0016323	basolateral plasma membrane
0.55	GO:0043034	costamere
0.48	GO:0030315	T-tubule
0.47	GO:0031430	M band
0.47	GO:0014704	intercalated disc
0.46	GO:0030018	Z disc
0.46	GO:0045121	membrane raft
0.45	GO:0043005	neuron projection
0.45	GO:0014069	postsynaptic density
0.43	GO:0048471	perinuclear region of cytoplasm

sp|Q01518|CAP1_HUMAN
Adenylyl cyclase-associated protein 1
Search

CAP1

0.74	Adenylyl cyclase-associated protein 1

0.71	GO:0007010	cytoskeleton organization
0.70	GO:0030029	actin filament-based process
0.54	GO:0001667	ameboidal-type cell migration
0.52	GO:0000902	cell morphogenesis
0.49	GO:0045761	regulation of adenylate cyclase activity
0.48	GO:0007163	establishment or maintenance of cell polarity
0.47	GO:0006898	receptor-mediated endocytosis
0.46	GO:0097435	supramolecular fiber organization
0.42	GO:0001756	somitogenesis
0.41	GO:0007165	signal transduction

0.73	GO:0003779	actin binding
0.51	GO:0008179	adenylate cyclase binding
0.40	GO:0042802	identical protein binding
0.33	GO:0003735	structural constituent of ribosome

0.55	GO:0030864	cortical actin cytoskeleton
0.48	GO:0005615	extracellular space
0.43	GO:0014069	postsynaptic density
0.37	GO:0005925	focal adhesion
0.36	GO:1903561	extracellular vesicle
0.36	GO:0035578	azurophil granule lumen
0.36	GO:0005886	plasma membrane
0.34	GO:0015934	large ribosomal subunit
0.34	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q01523|DEF5_HUMAN
Defensin-5
Search

0.97	Myeloid alpha defensin 9

0.72	GO:0006952	defense response
0.70	GO:0009617	response to bacterium
0.56	GO:0009620	response to fungus
0.56	GO:0031640	killing of cells of other organism
0.50	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide
0.48	GO:1905710	positive regulation of membrane permeability
0.43	GO:0002252	immune effector process
0.42	GO:0009615	response to virus
0.40	GO:0010818	T cell chemotaxis
0.39	GO:0002385	mucosal immune response

0.50

GO:0042803

protein homodimerization activity

0.73	GO:0005615	extracellular space
0.46	GO:0030141	secretory granule
0.46	GO:0005766	primary lysosome
0.45	GO:0005796	Golgi lumen
0.45	GO:0060205	cytoplasmic vesicle lumen
0.41	GO:0030133	transport vesicle
0.39	GO:0005775	vacuolar lumen
0.38	GO:1903561	extracellular vesicle
0.35	GO:0031012	extracellular matrix

sp|Q01524|DEF6_HUMAN
Defensin-6
Search

DEFA6

0.97	Neutrophil defensin 4

0.75	GO:0042742	defense response to bacterium
0.52	GO:0050832	defense response to fungus
0.51	GO:0031640	killing of cells of other organism
0.48	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide

0.66

GO:0042803

protein homodimerization activity

0.73	GO:0005615	extracellular space
0.48	GO:0005796	Golgi lumen

sp|Q01534|TSPY1_HUMAN
Testis-specific Y-encoded protein 1
Search

0.91	Testis-specific Y-encoded protein 1

0.79	GO:0006334	nucleosome assembly
0.46	GO:0007506	gonadal mesoderm development
0.43	GO:0007283	spermatogenesis
0.41	GO:0030154	cell differentiation
0.37	GO:0071480	cellular response to gamma radiation
0.37	GO:0051897	positive regulation of protein kinase B signaling
0.37	GO:0031398	positive regulation of protein ubiquitination
0.36	GO:0008284	positive regulation of cell proliferation
0.36	GO:0008283	cell proliferation
0.33	GO:0040008	regulation of growth

0.34

GO:0005515

protein binding

0.61	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm

sp|Q01538|MYT1_HUMAN
Myelin transcription factor 1
Search

MYT1

0.75	myelin transcription factor 1

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.34	GO:0007399	nervous system development
0.34	GO:0030154	cell differentiation
0.33	GO:0006351	transcription, DNA-templated
0.32	GO:1902679	negative regulation of RNA biosynthetic process

0.63	GO:0008270	zinc ion binding
0.61	GO:0003700	DNA binding transcription factor activity
0.32	GO:0003677	DNA binding

0.61	GO:0005634	nucleus
0.46	GO:0005829	cytosol
0.46	GO:0031974	membrane-enclosed lumen
0.42	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|Q01543|FLI1_HUMAN
Friend leukemia integration 1 transcription factor
Search

FLI1

0.92	Fli-1 proto-oncogene, ETS transcription factor

0.71	GO:0035855	megakaryocyte development
0.65	GO:0008015	blood circulation
0.63	GO:0009887	animal organ morphogenesis
0.62	GO:0006366	transcription by RNA polymerase II
0.61	GO:0045944	positive regulation of transcription by RNA polymerase II
0.38	GO:0051091	positive regulation of DNA binding transcription factor activity
0.38	GO:0001525	angiogenesis

0.69	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.66	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.65	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.63	GO:0003682	chromatin binding

0.64	GO:0016604	nuclear body
0.57	GO:0005829	cytosol

sp|Q01546|K22O_HUMAN
Keratin, type II cytoskeletal 2 oral
Search

0.90	Keratin, type II cytoskeletal 2 epidermal

0.53	GO:0045103	intermediate filament-based process
0.53	GO:0043588	skin development
0.52	GO:0009888	tissue development
0.50	GO:0007010	cytoskeleton organization
0.49	GO:0030154	cell differentiation
0.48	GO:0043473	pigmentation
0.47	GO:0048732	gland development
0.45	GO:0032980	keratinocyte activation
0.44	GO:0051546	keratinocyte migration
0.44	GO:0043616	keratinocyte proliferation

0.62	GO:0005198	structural molecule activity
0.39	GO:0008092	cytoskeletal protein binding
0.33	GO:0046982	protein heterodimerization activity

0.83	GO:0045095	keratin filament
0.43	GO:0001533	cornified envelope
0.41	GO:0009986	cell surface
0.41	GO:0070062	extracellular exosome
0.37	GO:0005829	cytosol
0.35	GO:0005634	nucleus

sp|Q01581|HMCS1_HUMAN
Hydroxymethylglutaryl-CoA synthase, cytoplasmic
Search

HMGCS1

0.67	3-hydroxy-3-methylglutaryl coenzyme A synthase

0.78	GO:0016126	sterol biosynthetic process
0.71	GO:0008299	isoprenoid biosynthetic process
0.46	GO:0014003	oligodendrocyte development
0.36	GO:0033197	response to vitamin E
0.35	GO:0071372	cellular response to follicle-stimulating hormone stimulus
0.35	GO:0071397	cellular response to cholesterol
0.35	GO:0009645	response to low light intensity stimulus
0.35	GO:0071404	cellular response to low-density lipoprotein particle stimulus
0.35	GO:0001700	embryonic development via the syncytial blastoderm
0.35	GO:0046690	response to tellurium ion

0.83	GO:0004421	hydroxymethylglutaryl-CoA synthase activity
0.35	GO:0008009	chemokine activity
0.34	GO:0042803	protein homodimerization activity
0.34	GO:0043177	organic acid binding
0.33	GO:0016853	isomerase activity
0.32	GO:0008144	drug binding

0.34	GO:0005829	cytosol
0.33	GO:0005576	extracellular region

0.83	EC:2.3.3.10	GO:0004421
0.83	KEGG:R01978	GO:0004421

sp|Q01628|IFM3_HUMAN
Interferon-induced transmembrane protein 3
Search

IFITM3

0.89	Interferon-induced transmembrane protein 3

0.70	GO:0009607	response to biotic stimulus
0.45	GO:0046597	negative regulation of viral entry into host cell
0.44	GO:0035455	response to interferon-alpha
0.44	GO:0035456	response to interferon-beta
0.43	GO:0045071	negative regulation of viral genome replication
0.43	GO:0034341	response to interferon-gamma
0.41	GO:0002252	immune effector process
0.40	GO:0060337	type I interferon signaling pathway
0.40	GO:0009605	response to external stimulus
0.39	GO:0051704	multi-organism process

0.34	GO:0005515	protein binding
0.34	GO:0005057	signal transducer activity, downstream of receptor

0.37	GO:0031902	late endosome membrane
0.37	GO:0005765	lysosomal membrane
0.36	GO:0005886	plasma membrane
0.35	GO:0045177	apical part of cell
0.35	GO:0009986	cell surface
0.35	GO:0070062	extracellular exosome
0.34	GO:0005783	endoplasmic reticulum
0.33	GO:0005634	nucleus
0.33	GO:0005769	early endosome
0.30	GO:0031224	intrinsic component of membrane

sp|Q01629|IFM2_HUMAN
Interferon-induced transmembrane protein 2
Search

IFITM3

0.92	Interferon-induced transmembrane protein 2

0.70	GO:0009607	response to biotic stimulus
0.45	GO:0046597	negative regulation of viral entry into host cell
0.44	GO:0035455	response to interferon-alpha
0.44	GO:0035456	response to interferon-beta
0.43	GO:0045071	negative regulation of viral genome replication
0.43	GO:0034341	response to interferon-gamma
0.41	GO:0002252	immune effector process
0.40	GO:0060337	type I interferon signaling pathway
0.40	GO:0009605	response to external stimulus
0.39	GO:0051704	multi-organism process

0.34	GO:0005515	protein binding
0.34	GO:0005057	signal transducer activity, downstream of receptor

0.37	GO:0031902	late endosome membrane
0.37	GO:0005765	lysosomal membrane
0.36	GO:0005886	plasma membrane
0.35	GO:0045177	apical part of cell
0.35	GO:0009986	cell surface
0.35	GO:0070062	extracellular exosome
0.34	GO:0005783	endoplasmic reticulum
0.33	GO:0005769	early endosome
0.33	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|Q01638|ILRL1_HUMAN
Interleukin-1 receptor-like 1
Search

IL1RL1

0.95	Interleukin 1 receptor like 1

0.77	GO:0019221	cytokine-mediated signaling pathway
0.66	GO:0002826	negative regulation of T-helper 1 type immune response
0.64	GO:0090197	positive regulation of chemokine secretion
0.64	GO:0032754	positive regulation of interleukin-5 production
0.63	GO:0043032	positive regulation of macrophage activation
0.63	GO:0032689	negative regulation of interferon-gamma production
0.61	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling
0.60	GO:0050729	positive regulation of inflammatory response
0.39	GO:0045079	negative regulation of chemokine biosynthetic process
0.38	GO:0006953	acute-phase response

0.85	GO:0004908	interleukin-1 receptor activity
0.67	GO:0002113	interleukin-33 binding
0.66	GO:0002114	interleukin-33 receptor activity
0.37	GO:0005057	signal transducer activity, downstream of receptor
0.34	GO:0019966	interleukin-1 binding
0.34	GO:0005161	platelet-derived growth factor receptor binding
0.33	GO:0002020	protease binding

0.59	GO:0009897	external side of plasma membrane
0.55	GO:0005578	proteinaceous extracellular matrix
0.35	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane

sp|Q01650|LAT1_HUMAN
Large neutral amino acids transporter small subunit 1
Search

SLC7A5

0.94	Solute carrier family 7 (amino acid transporter light chain, L system), member 5

0.69	GO:0006865	amino acid transport
0.58	GO:1903825	organic acid transmembrane transport
0.56	GO:0098656	anion transmembrane transport

0.62	GO:0015179	L-amino acid transmembrane transporter activity
0.50	GO:0015175	neutral amino acid transmembrane transporter activity
0.48	GO:0015297	antiporter activity

0.54	GO:0005829	cytosol
0.47	GO:0005886	plasma membrane
0.46	GO:0043231	intracellular membrane-bounded organelle
0.30	GO:0016021	integral component of membrane

sp|Q01658|NC2B_HUMAN
Protein Dr1
Search

DR1

0.97	Down-regulator of transcription 1

0.54	GO:0043966	histone H3 acetylation
0.35	GO:0006351	transcription, DNA-templated
0.35	GO:1903506	regulation of nucleic acid-templated transcription
0.35	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.35	GO:0010468	regulation of gene expression
0.34	GO:1902679	negative regulation of RNA biosynthetic process
0.33	GO:0006897	endocytosis

0.74	GO:0046982	protein heterodimerization activity
0.53	GO:0017025	TBP-class protein binding
0.34	GO:0003714	transcription corepressor activity
0.34	GO:0003677	DNA binding

0.58	GO:0005634	nucleus
0.51	GO:0031248	protein acetyltransferase complex
0.47	GO:0031974	membrane-enclosed lumen
0.43	GO:0043234	protein complex
0.42	GO:0044446	intracellular organelle part

sp|Q01664|TFAP4_HUMAN
Transcription factor AP-4
Search

TFAP4

0.95	Transcription factor AP-4 (Activating enhancer binding protein 4)

0.60	GO:0043922	negative regulation by host of viral transcription
0.60	GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
0.60	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
0.60	GO:0043923	positive regulation by host of viral transcription
0.59	GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity
0.59	GO:0071549	cellular response to dexamethasone stimulus
0.59	GO:0071157	negative regulation of cell cycle arrest
0.58	GO:0043392	negative regulation of DNA binding
0.55	GO:0008285	negative regulation of cell proliferation
0.54	GO:1901990	regulation of mitotic cell cycle phase transition

0.68	GO:0046983	protein dimerization activity
0.59	GO:0070888	E-box binding
0.58	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.57	GO:0042826	histone deacetylase binding
0.56	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.52	GO:0042802	identical protein binding
0.36	GO:0003713	transcription coactivator activity

0.55	GO:0017053	transcriptional repressor complex
0.47	GO:0005634	nucleus
0.45	GO:0005739	mitochondrion

sp|Q01668|CAC1D_HUMAN
Voltage-dependent L-type calcium channel subunit alpha-1D
Search

CACNA1D

0.73	Voltage-dependent L-type calcium channel subunit alpha

0.77	GO:0034765	regulation of ion transmembrane transport
0.77	GO:0070588	calcium ion transmembrane transport
0.55	GO:0086046	membrane depolarization during SA node cell action potential
0.53	GO:0086002	cardiac muscle cell action potential involved in contraction
0.53	GO:0086091	regulation of heart rate by cardiac conduction
0.52	GO:0051928	positive regulation of calcium ion transport
0.52	GO:0070509	calcium ion import
0.52	GO:0007605	sensory perception of sound
0.51	GO:0043266	regulation of potassium ion transport
0.50	GO:0022898	regulation of transmembrane transporter activity

0.82	GO:0005245	voltage-gated calcium channel activity
0.53	GO:0051393	alpha-actinin binding
0.53	GO:0030506	ankyrin binding
0.35	GO:0046872	metal ion binding
0.34	GO:0030165	PDZ domain binding

0.81	GO:0005891	voltage-gated calcium channel complex
0.53	GO:0030315	T-tubule
0.51	GO:0030018	Z disc
0.39	GO:0097470	ribbon synapse
0.38	GO:0009925	basal plasma membrane
0.34	GO:0032590	dendrite membrane
0.34	GO:0016324	apical plasma membrane
0.34	GO:0005887	integral component of plasma membrane
0.34	GO:0043025	neuronal cell body
0.32	GO:0005634	nucleus

sp|Q01718|ACTHR_HUMAN
Adrenocorticotropic hormone receptor
Search

MC2R

0.97	Adrenocorticotropic hormone receptor

0.71	GO:0007218	neuropeptide signaling pathway
0.57	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
0.42	GO:0030819	positive regulation of cAMP biosynthetic process
0.41	GO:0060259	regulation of feeding behavior
0.41	GO:0032501	multicellular organismal process
0.39	GO:0003006	developmental process involved in reproduction
0.39	GO:0048521	negative regulation of behavior
0.38	GO:0048856	anatomical structure development
0.37	GO:0045475	locomotor rhythm
0.37	GO:0040008	regulation of growth

0.84	GO:0004977	melanocortin receptor activity
0.73	GO:0008188	neuropeptide receptor activity
0.38	GO:0042923	neuropeptide binding
0.34	GO:0005515	protein binding
0.33	GO:0003924	GTPase activity
0.33	GO:0005200	structural constituent of cytoskeleton
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.54	GO:0005886	plasma membrane
0.38	GO:0005622	intracellular
0.33	GO:0099512	supramolecular fiber
0.32	GO:0043228	non-membrane-bounded organelle
0.32	GO:0044422	organelle part
0.30	GO:0016021	integral component of membrane

sp|Q01726|MSHR_HUMAN
Melanocyte-stimulating hormone receptor
Search

MC1R

0.69	Melanocyte-stimulating hormone receptor

0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.37	GO:0090037	positive regulation of protein kinase C signaling
0.37	GO:0010739	positive regulation of protein kinase A signaling
0.36	GO:0051897	positive regulation of protein kinase B signaling
0.36	GO:0043473	pigmentation
0.35	GO:0045944	positive regulation of transcription by RNA polymerase II
0.35	GO:0009650	UV protection
0.35	GO:0032720	negative regulation of tumor necrosis factor production
0.35	GO:0070914	UV-damage excision repair
0.34	GO:0042438	melanin biosynthetic process

0.84	GO:0004980	melanocyte-stimulating hormone receptor activity
0.34	GO:0031625	ubiquitin protein ligase binding
0.34	GO:0005200	structural constituent of cytoskeleton
0.33	GO:0003924	GTPase activity
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.55	GO:0005886	plasma membrane
0.34	GO:0005874	microtubule
0.30	GO:0016021	integral component of membrane

sp|Q01740|FMO1_HUMAN
Dimethylaniline monooxygenase [N-oxide-forming] 1
Search

FMO1

0.60	Flavin-containing monooxygenase

0.64	GO:0070995	NADPH oxidation
0.52	GO:0009404	toxin metabolic process
0.49	GO:0072592	oxygen metabolic process
0.44	GO:0006805	xenobiotic metabolic process
0.44	GO:0006082	organic acid metabolic process
0.39	GO:0032496	response to lipopolysaccharide
0.39	GO:0006970	response to osmotic stress
0.37	GO:0042737	drug catabolic process

0.78	GO:0004499	N,N-dimethylaniline monooxygenase activity
0.69	GO:0050661	NADP binding
0.65	GO:0050660	flavin adenine dinucleotide binding
0.37	GO:0034899	trimethylamine monooxygenase activity
0.33	GO:0005515	protein binding

0.42	GO:0005783	endoplasmic reticulum
0.42	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.41	GO:0031984	organelle subcompartment
0.39	GO:0031090	organelle membrane
0.35	GO:0005829	cytosol
0.34	GO:0043233	organelle lumen
0.30	GO:0016021	integral component of membrane

0.78	EC:1.14.13.8	GO:0004499
0.37	KEGG:R05623	GO:0034899

sp|Q01780|EXOSX_HUMAN
Exosome component 10
Search

EXOSC10

0.93	Exosome component 10

0.62	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.61	GO:0006396	RNA processing
0.61	GO:0071048	nuclear retention of unspliced pre-mRNA at the site of transcription
0.59	GO:0071044	histone mRNA catabolic process
0.59	GO:1904872	regulation of telomerase RNA localization to Cajal body
0.58	GO:0071034	CUT catabolic process
0.58	GO:0032211	negative regulation of telomere maintenance via telomerase
0.58	GO:0009048	dosage compensation by inactivation of X chromosome
0.57	GO:0071035	nuclear polyadenylation-dependent rRNA catabolic process
0.48	GO:0042254	ribosome biogenesis

0.70	GO:0008408	3'-5' exonuclease activity
0.52	GO:0016896	exoribonuclease activity, producing 5'-phosphomonoesters
0.51	GO:1901265	nucleoside phosphate binding
0.50	GO:0003676	nucleic acid binding
0.50	GO:0036094	small molecule binding
0.34	GO:0016740	transferase activity
0.34	GO:0005515	protein binding

0.80	GO:0000176	nuclear exosome (RNase complex)
0.57	GO:0035327	transcriptionally active chromatin
0.51	GO:0005730	nucleolus
0.49	GO:0005829	cytosol
0.34	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

0.52

EC:3.1.13

GO:0016896

sp|Q01804|OTUD4_HUMAN
OTU domain-containing protein 4
Search

OTUD4

0.97	OTU domain-containing protein 4

0.81	GO:0071108	protein K48-linked deubiquitination
0.41	GO:0006397	mRNA processing
0.36	GO:0021549	cerebellum development
0.36	GO:0009953	dorsal/ventral pattern formation
0.36	GO:0043010	camera-type eye development

0.76	GO:0004843	thiol-dependent ubiquitin-specific protease activity
0.41	GO:0003723	RNA binding
0.37	GO:0005515	protein binding

0.38	GO:0005634	nucleus
0.35	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q01813|PFKAP_HUMAN
ATP-dependent 6-phosphofructokinase, platelet type
Search

PFKP

0.44	ATP-dependent 6-phosphofructokinase, platelet type

0.79	GO:0006002	fructose 6-phosphate metabolic process
0.78	GO:0061615	glycolytic process through fructose-6-phosphate
0.52	GO:1990830	cellular response to leukemia inhibitory factor
0.35	GO:0061718	glucose catabolic process to pyruvate
0.35	GO:0006735	NADH regeneration
0.35	GO:0051289	protein homotetramerization
0.34	GO:0030388	fructose 1,6-bisphosphate metabolic process

0.79	GO:0003872	6-phosphofructokinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0046872	metal ion binding
0.50	GO:0045296	cadherin binding
0.48	GO:0032403	protein complex binding
0.36	GO:0042802	identical protein binding
0.35	GO:0070095	fructose-6-phosphate binding

0.49	GO:0005737	cytoplasm
0.36	GO:0031012	extracellular matrix
0.36	GO:0070062	extracellular exosome
0.34	GO:0061695	transferase complex, transferring phosphorus-containing groups
0.34	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.79

EC:2.7.1.11

GO:0003872

sp|Q01814|AT2B2_HUMAN
Plasma membrane calcium-transporting ATPase 2
Search

ATP2B2

0.58	Calcium-transporting ATPase

0.77	GO:0070588	calcium ion transmembrane transport
0.69	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.53	GO:0006874	cellular calcium ion homeostasis
0.52	GO:0007605	sensory perception of sound
0.50	GO:0030182	neuron differentiation
0.37	GO:0045299	otolith mineralization
0.37	GO:0021684	cerebellar granular layer formation
0.37	GO:1901660	calcium ion export
0.37	GO:0021694	cerebellar Purkinje cell layer formation
0.37	GO:0042428	serotonin metabolic process

0.80	GO:0005388	calcium-transporting ATPase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.47	GO:0030165	PDZ domain binding
0.38	GO:0005516	calmodulin binding
0.38	GO:0008022	protein C-terminus binding
0.37	GO:0030899	calcium-dependent ATPase activity
0.36	GO:0005509	calcium ion binding

0.42	GO:0005887	integral component of plasma membrane
0.38	GO:0005737	cytoplasm
0.38	GO:0043231	intracellular membrane-bounded organelle
0.37	GO:0045202	synapse
0.36	GO:0030054	cell junction
0.36	GO:0070062	extracellular exosome
0.36	GO:0005929	cilium
0.36	GO:0016324	apical plasma membrane
0.36	GO:0043025	neuronal cell body
0.35	GO:0044298	cell body membrane

0.80

EC:3.6.3.8

GO:0005388

sp|Q01826|SATB1_HUMAN
DNA-binding protein SATB1
Search

SATB1

0.89	DNA-binding protein SATB

0.62	GO:0050798	activated T cell proliferation
0.61	GO:0043374	CD8-positive, alpha-beta T cell differentiation
0.60	GO:0060004	reflex
0.59	GO:0043367	CD4-positive, alpha-beta T cell differentiation
0.56	GO:0008544	epidermis development
0.56	GO:0000122	negative regulation of transcription by RNA polymerase II
0.54	GO:0016571	histone methylation
0.54	GO:0006338	chromatin remodeling
0.53	GO:0006351	transcription, DNA-templated
0.47	GO:0030223	neutrophil differentiation

0.59	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.56	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.54	GO:0003682	chromatin binding

0.60	GO:0016605	PML body
0.58	GO:0016363	nuclear matrix
0.57	GO:0005720	nuclear heterochromatin

sp|Q01831|XPC_HUMAN
DNA repair protein complementing XP-C cells
Search

XPC

0.93	XPC complex subunit, DNA damage recognition and repair factor

0.76	GO:0070914	UV-damage excision repair
0.75	GO:0010224	response to UV-B
0.74	GO:0031573	intra-S DNA damage checkpoint
0.73	GO:0006289	nucleotide-excision repair
0.69	GO:1901990	regulation of mitotic cell cycle phase transition
0.60	GO:0051276	chromosome organization
0.54	GO:0006298	mismatch repair
0.40	GO:0010996	response to auditory stimulus
0.37	GO:0042493	response to drug

0.73	GO:0003684	damaged DNA binding
0.68	GO:0003697	single-stranded DNA binding

0.84	GO:0071942	XPC complex
0.65	GO:0005730	nucleolus
0.62	GO:0000111	nucleotide-excision repair factor 2 complex
0.55	GO:0005739	mitochondrion
0.51	GO:0005886	plasma membrane
0.39	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

sp|Q01844|EWS_HUMAN
RNA-binding protein EWS
Search

EWSR1

0.95	RNA-binding protein EWS

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.34	GO:0000413	protein peptidyl-prolyl isomerization
0.33	GO:0006351	transcription, DNA-templated

0.58	GO:0003723	RNA binding
0.50	GO:0046872	metal ion binding
0.47	GO:0042802	identical protein binding
0.35	GO:0005516	calmodulin binding
0.34	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.32	GO:0043565	sequence-specific DNA binding
0.32	GO:0003700	DNA binding transcription factor activity

0.47	GO:0005730	nucleolus
0.37	GO:0015030	Cajal body
0.33	GO:0005737	cytoplasm
0.33	GO:0005886	plasma membrane

0.34

GO:0003755

sp|Q01850|CDR2_HUMAN
Cerebellar degeneration-related protein 2
Search

CDR2

0.91	Paraneoplastic cerebellar degeneration-associated antigen

0.37

GO:0006457

protein folding

0.38	GO:0005515	protein binding
0.34	GO:0032550	purine ribonucleoside binding
0.34	GO:0019001	guanyl nucleotide binding
0.33	GO:0032555	purine ribonucleotide binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.48	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

sp|Q01851|PO4F1_HUMAN
POU domain, class 4, transcription factor 1
Search

POU4F1

0.95	POU domain, class 4, transcription factor 1

0.58	GO:0045672	positive regulation of osteoclast differentiation
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:0050885	neuromuscular process controlling balance
0.56	GO:0010468	regulation of gene expression
0.55	GO:0048513	animal organ development
0.54	GO:0007399	nervous system development
0.53	GO:0007600	sensory perception
0.53	GO:1902867	negative regulation of retina development in camera-type eye

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0003714	transcription corepressor activity
0.53	GO:0001012	RNA polymerase II regulatory region DNA binding
0.52	GO:0003682	chromatin binding
0.50	GO:0003690	double-stranded DNA binding
0.48	GO:0035326	enhancer binding
0.47	GO:0003713	transcription coactivator activity
0.44	GO:0003697	single-stranded DNA binding
0.44	GO:0051020	GTPase binding

0.61	GO:0005634	nucleus
0.48	GO:0070013	intracellular organelle lumen
0.45	GO:0043005	neuron projection
0.44	GO:0000785	chromatin
0.39	GO:0005737	cytoplasm
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q01860|PO5F1_HUMAN
POU domain, class 5, transcription factor 1
Search

POU5F1

0.54	POU domain, class 5, transcription factor 1

0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.55	GO:0006351	transcription, DNA-templated
0.47	GO:0001711	endodermal cell fate commitment
0.46	GO:0009786	regulation of asymmetric cell division
0.46	GO:0001712	ectodermal cell fate commitment
0.46	GO:0010604	positive regulation of macromolecule metabolic process
0.46	GO:0045955	negative regulation of calcium ion-dependent exocytosis
0.45	GO:0001829	trophectodermal cell differentiation

0.61	GO:0043565	sequence-specific DNA binding
0.60	GO:0003700	DNA binding transcription factor activity
0.50	GO:0035326	enhancer binding
0.50	GO:0019955	cytokine binding
0.46	GO:0003690	double-stranded DNA binding
0.46	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding
0.44	GO:0031625	ubiquitin protein ligase binding
0.44	GO:0031490	chromatin DNA binding
0.43	GO:0003714	transcription corepressor activity
0.42	GO:0001012	RNA polymerase II regulatory region DNA binding

0.60	GO:0005634	nucleus
0.45	GO:0000785	chromatin
0.45	GO:0070013	intracellular organelle lumen
0.43	GO:0017053	transcriptional repressor complex
0.42	GO:0005667	transcription factor complex
0.40	GO:0005829	cytosol
0.37	GO:0005739	mitochondrion

sp|Q01892|SPIB_HUMAN
Transcription factor Spi-B
Search

SPI1

0.94	Transcription factor Spi-B

0.61	GO:0030225	macrophage differentiation
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.51	GO:0044027	hypermethylation of CpG island
0.51	GO:0030851	granulocyte differentiation
0.51	GO:0045347	negative regulation of MHC class II biosynthetic process
0.51	GO:0045646	regulation of erythrocyte differentiation
0.51	GO:0090241	negative regulation of histone H4 acetylation
0.50	GO:0061614	pri-miRNA transcription by RNA polymerase II

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.51	GO:0051525	NFAT protein binding
0.50	GO:0035326	enhancer binding
0.48	GO:0001012	RNA polymerase II regulatory region DNA binding
0.48	GO:0001047	core promoter binding
0.47	GO:0001085	RNA polymerase II transcription factor binding
0.46	GO:0003690	double-stranded DNA binding
0.33	GO:0003723	RNA binding
0.33	GO:0008408	3'-5' exonuclease activity

0.61	GO:0005634	nucleus
0.44	GO:0000785	chromatin
0.42	GO:0031974	membrane-enclosed lumen
0.35	GO:0005667	transcription factor complex
0.32	GO:0005737	cytoplasm

0.33

GO:0003887

sp|Q01954|BNC1_HUMAN
Zinc finger protein basonuclin-1
Search

BNC1

0.95	Zinc finger protein basonuclin-1

0.41	GO:0007283	spermatogenesis
0.41	GO:0008284	positive regulation of cell proliferation
0.40	GO:0032502	developmental process
0.38	GO:0006356	regulation of transcription by RNA polymerase I
0.38	GO:0050678	regulation of epithelial cell proliferation
0.37	GO:0042060	wound healing
0.37	GO:0040007	growth
0.37	GO:0006351	transcription, DNA-templated
0.36	GO:0006357	regulation of transcription by RNA polymerase II
0.35	GO:0051276	chromosome organization

0.51	GO:0003676	nucleic acid binding
0.36	GO:0046872	metal ion binding
0.35	GO:0003700	DNA binding transcription factor activity
0.35	GO:0005515	protein binding

0.44	GO:0005654	nucleoplasm
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q01955|CO4A3_HUMAN
Collagen alpha-3(IV) chain
Search

COL4A5

0.80	Collagen type IV alpha 5 transcript variant 2

0.61	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.54	GO:0072577	endothelial cell apoptotic process
0.53	GO:0072001	renal system development
0.52	GO:0030198	extracellular matrix organization
0.52	GO:0007528	neuromuscular junction development
0.51	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process
0.50	GO:0016525	negative regulation of angiogenesis
0.49	GO:0048513	animal organ development
0.49	GO:0008283	cell proliferation
0.44	GO:0001569	branching involved in blood vessel morphogenesis

0.80	GO:0005201	extracellular matrix structural constituent
0.51	GO:0005178	integrin binding
0.44	GO:0048407	platelet-derived growth factor binding
0.34	GO:0008191	metalloendopeptidase inhibitor activity

0.80	GO:0005604	basement membrane
0.77	GO:0005581	collagen trimer
0.63	GO:0098645	collagen network
0.48	GO:0031594	neuromuscular junction
0.45	GO:0005783	endoplasmic reticulum
0.40	GO:0005615	extracellular space
0.33	GO:0043233	organelle lumen
0.32	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|Q01959|SC6A3_HUMAN
Sodium-dependent dopamine transporter
Search

SLC6A3

0.65	Solute carrier family 6 (neurotransmitter transporter), member 3

0.81	GO:0015872	dopamine transport
0.76	GO:0006836	neurotransmitter transport
0.73	GO:0090493	catecholamine uptake
0.68	GO:0042420	dopamine catabolic process
0.67	GO:0060134	prepulse inhibition
0.67	GO:0042416	dopamine biosynthetic process
0.67	GO:0042053	regulation of dopamine metabolic process
0.67	GO:0021984	adenohypophysis development
0.66	GO:0007595	lactation
0.66	GO:0042220	response to cocaine

0.83	GO:0005330	dopamine:sodium symporter activity
0.67	GO:0035240	dopamine binding
0.64	GO:0047485	protein N-terminus binding

0.67	GO:0016600	flotillin complex
0.63	GO:0043005	neuron projection
0.61	GO:0043025	neuronal cell body
0.61	GO:0005887	integral component of plasma membrane
0.59	GO:0098793	presynapse
0.58	GO:0009986	cell surface

sp|Q01968|OCRL_HUMAN
Inositol polyphosphate 5-phosphatase OCRL-1
Search

OCRL

0.94	Oculocerebrorenal syndrome of Lowe

0.80	GO:0046856	phosphatidylinositol dephosphorylation
0.60	GO:0007165	signal transduction
0.56	GO:0060271	cilium assembly
0.53	GO:0043009	chordate embryonic development
0.52	GO:0043547	positive regulation of GTPase activity
0.43	GO:0071871	response to epinephrine
0.42	GO:0097205	renal filtration
0.42	GO:0048884	neuromast development
0.42	GO:0032402	melanosome transport
0.42	GO:0001755	neural crest cell migration

0.79	GO:0052745	inositol phosphate phosphatase activity
0.62	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
0.57	GO:0048365	Rac GTPase binding
0.52	GO:0005096	GTPase activator activity
0.36	GO:0043813	phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity
0.36	GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity
0.33	GO:0030246	carbohydrate binding

0.56	GO:0001750	photoreceptor outer segment
0.54	GO:0005769	early endosome
0.54	GO:0005802	trans-Golgi network
0.54	GO:0030136	clathrin-coated vesicle
0.45	GO:0005634	nucleus
0.42	GO:0005886	plasma membrane
0.39	GO:0030670	phagocytic vesicle membrane
0.38	GO:0005905	clathrin-coated pit
0.38	GO:0010008	endosome membrane
0.37	GO:0070062	extracellular exosome

0.79	EC:3.1.3	GO:0052745
0.62	KEGG:R04404	GO:0004439

sp|Q01970|PLCB3_HUMAN
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3
Search

PLCB3

0.53	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3

0.77	GO:0003073	regulation of systemic arterial blood pressure
0.69	GO:0016042	lipid catabolic process
0.64	GO:0043647	inositol phosphate metabolic process
0.63	GO:0035556	intracellular signal transduction
0.62	GO:0007223	Wnt signaling pathway, calcium modulating pathway
0.59	GO:0007186	G-protein coupled receptor signaling pathway
0.55	GO:0006892	post-Golgi vesicle-mediated transport
0.51	GO:0046488	phosphatidylinositol metabolic process
0.50	GO:0046434	organophosphate catabolic process
0.46	GO:0044248	cellular catabolic process

0.78	GO:0004435	phosphatidylinositol phospholipase C activity
0.74	GO:0045296	cadherin binding
0.72	GO:0005516	calmodulin binding
0.67	GO:0005509	calcium ion binding
0.60	GO:0004871	signal transducer activity
0.37	GO:0005521	lamin binding
0.37	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.36	GO:0005096	GTPase activator activity
0.35	GO:0019899	enzyme binding

0.58	GO:0005654	nucleoplasm
0.57	GO:0005829	cytosol
0.56	GO:0042383	sarcolemma
0.55	GO:0043234	protein complex
0.37	GO:0043209	myelin sheath
0.36	GO:0031965	nuclear membrane
0.36	GO:0000790	nuclear chromatin

0.78	EC:3.1.4.11	GO:0004435
0.78	KEGG:R03435	GO:0004435

sp|Q01973|ROR1_HUMAN
Inactive tyrosine-protein kinase transmembrane receptor ROR1
Search

ROR1

0.96	Receptor tyrosine kinase like orphan receptor 1

0.78	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.65	GO:0048839	inner ear development
0.63	GO:0006468	protein phosphorylation
0.62	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.62	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.62	GO:0016055	Wnt signaling pathway
0.61	GO:0007605	sensory perception of sound
0.50	GO:0030538	embryonic genitalia morphogenesis
0.49	GO:0001502	cartilage condensation
0.48	GO:0060395	SMAD protein signal transduction

0.68	GO:0017147	Wnt-protein binding
0.64	GO:0004672	protein kinase activity
0.63	GO:0042813	Wnt-activated receptor activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0005109	frizzled binding
0.37	GO:0046982	protein heterodimerization activity

0.62	GO:0043679	axon terminus
0.59	GO:0043235	receptor complex
0.45	GO:0005886	plasma membrane
0.37	GO:0097517	contractile actin filament bundle
0.37	GO:0042641	actomyosin
0.36	GO:0009986	cell surface
0.33	GO:0005737	cytoplasm
0.30	GO:0016021	integral component of membrane

sp|Q01974|ROR2_HUMAN
Tyrosine-protein kinase transmembrane receptor ROR2
Search

ROR2

0.92	Receptor tyrosine kinase like orphan receptor 2

0.71	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.67	GO:0030538	embryonic genitalia morphogenesis
0.66	GO:0007223	Wnt signaling pathway, calcium modulating pathway
0.65	GO:0001502	cartilage condensation
0.63	GO:0060071	Wnt signaling pathway, planar cell polarity pathway
0.63	GO:0006468	protein phosphorylation
0.63	GO:0060395	SMAD protein signal transduction
0.63	GO:0042733	embryonic digit morphogenesis
0.62	GO:0001756	somitogenesis
0.62	GO:0048839	inner ear development

0.65	GO:0017147	Wnt-protein binding
0.64	GO:0005109	frizzled binding
0.64	GO:0004672	protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.43	GO:0046982	protein heterodimerization activity
0.41	GO:0042813	Wnt-activated receptor activity

0.41	GO:0043005	neuron projection
0.40	GO:0120038	plasma membrane bounded cell projection part
0.39	GO:0098793	presynapse
0.39	GO:0043235	receptor complex
0.39	GO:0005622	intracellular
0.37	GO:0043025	neuronal cell body
0.36	GO:0009986	cell surface
0.35	GO:0099512	supramolecular fiber
0.35	GO:0005886	plasma membrane
0.34	GO:0043228	non-membrane-bounded organelle

sp|Q01995|TAGL_HUMAN
Transgelin
Search

TAGLN

0.82	Transgelin

0.52	GO:0030855	epithelial cell differentiation
0.39	GO:0007010	cytoskeleton organization
0.38	GO:0000122	negative regulation of transcription by RNA polymerase II
0.38	GO:0000902	cell morphogenesis
0.38	GO:0030029	actin filament-based process
0.37	GO:0033227	dsRNA transport
0.35	GO:0007517	muscle organ development

0.77	GO:0051015	actin filament binding
0.37	GO:0051032	nucleic acid transmembrane transporter activity
0.34	GO:0030674	protein binding, bridging

0.39	GO:0043209	myelin sheath
0.38	GO:0015629	actin cytoskeleton
0.36	GO:0005634	nucleus
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q02040|AK17A_HUMAN
A-kinase anchor protein 17A
Search

AKAP17A

0.96	Splicing factor arginine/serine-rich 17

0.75	GO:0043484	regulation of RNA splicing
0.47	GO:0016310	phosphorylation
0.36	GO:0042113	B cell activation
0.36	GO:0008380	RNA splicing
0.35	GO:0006397	mRNA processing
0.34	GO:0032259	methylation
0.34	GO:0007165	signal transduction
0.33	GO:0006606	protein import into nucleus
0.33	GO:1903506	regulation of nucleic acid-templated transcription
0.33	GO:2000112	regulation of cellular macromolecule biosynthetic process

0.77	GO:0051018	protein kinase A binding
0.49	GO:0016301	kinase activity
0.48	GO:0003676	nucleic acid binding
0.36	GO:0008171	O-methyltransferase activity
0.34	GO:0061608	nuclear import signal receptor activity
0.31	GO:0004930	G-protein coupled receptor activity

0.51	GO:0016607	nuclear speck
0.46	GO:0005829	cytosol
0.36	GO:0005681	spliceosomal complex
0.30	GO:0031224	intrinsic component of membrane

0.36

GO:0008171

sp|Q02045|MYL5_HUMAN
Myosin light chain 5
Search

MYL5

0.84	Cardiac ventricular myosin light chain-2

0.54	GO:0098735	positive regulation of the force of heart contraction
0.53	GO:0042694	muscle cell fate specification
0.52	GO:0055003	cardiac myofibril assembly
0.51	GO:0060047	heart contraction
0.50	GO:0055010	ventricular cardiac muscle tissue morphogenesis
0.50	GO:0048747	muscle fiber development
0.50	GO:0006941	striated muscle contraction
0.49	GO:0030308	negative regulation of cell growth
0.48	GO:0009791	post-embryonic development
0.36	GO:0006937	regulation of muscle contraction

0.70	GO:0005509	calcium ion binding
0.50	GO:0003785	actin monomer binding
0.37	GO:0008307	structural constituent of muscle
0.35	GO:0032036	myosin heavy chain binding
0.33	GO:0004674	protein serine/threonine kinase activity
0.32	GO:0032559	adenyl ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.52	GO:0097512	cardiac myofibril
0.47	GO:0015629	actin cytoskeleton
0.41	GO:0044449	contractile fiber part
0.38	GO:0044430	cytoskeletal part
0.37	GO:0005739	mitochondrion
0.36	GO:0043234	protein complex
0.35	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.33

GO:0004674

sp|Q02078|MEF2A_HUMAN
Myocyte-specific enhancer factor 2A
Search

MEF2A

0.94	Myocyte-specific enhancer factor 2A

0.72	GO:0045944	positive regulation of transcription by RNA polymerase II
0.60	GO:0070375	ERK5 cascade
0.59	GO:0055005	ventricular cardiac myofibril assembly
0.57	GO:0006351	transcription, DNA-templated
0.56	GO:0014742	positive regulation of muscle hypertrophy
0.56	GO:0061337	cardiac conduction
0.56	GO:0071277	cellular response to calcium ion
0.55	GO:0010611	regulation of cardiac muscle hypertrophy
0.54	GO:0048311	mitochondrion distribution
0.54	GO:0000002	mitochondrial genome maintenance

0.75	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.67	GO:0046983	protein dimerization activity
0.57	GO:0035035	histone acetyltransferase binding
0.55	GO:0033613	activating transcription factor binding
0.55	GO:0042826	histone deacetylase binding
0.55	GO:0046332	SMAD binding
0.55	GO:0001105	RNA polymerase II transcription coactivator activity
0.54	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.53	GO:0001085	RNA polymerase II transcription factor binding
0.53	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding

0.60	GO:0005634	nucleus
0.50	GO:0005667	transcription factor complex
0.48	GO:0000785	chromatin
0.47	GO:0005829	cytosol
0.47	GO:0031974	membrane-enclosed lumen
0.30	GO:0016020	membrane

sp|Q02080|MEF2B_HUMAN
Myocyte-specific enhancer factor 2B
Search

MEF2B

0.94	LOW QUALITY PROTEIN: myocyte-specific enhancer factor 2B

0.74	GO:0045944	positive regulation of transcription by RNA polymerase II
0.58	GO:0006351	transcription, DNA-templated
0.43	GO:0061061	muscle structure development
0.41	GO:0007512	adult heart development
0.41	GO:0001958	endochondral ossification
0.41	GO:1904707	positive regulation of vascular smooth muscle cell proliferation
0.41	GO:0002062	chondrocyte differentiation
0.40	GO:0001649	osteoblast differentiation
0.40	GO:0014706	striated muscle tissue development
0.38	GO:0031034	myosin filament assembly

0.77	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.68	GO:0046983	protein dimerization activity
0.52	GO:0042826	histone deacetylase binding
0.50	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.49	GO:0000987	proximal promoter sequence-specific DNA binding
0.40	GO:0033613	activating transcription factor binding
0.38	GO:0042802	identical protein binding
0.37	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding
0.37	GO:0001158	enhancer sequence-specific DNA binding
0.34	GO:0008289	lipid binding

0.61	GO:0005634	nucleus
0.46	GO:0005667	transcription factor complex
0.37	GO:0043233	organelle lumen
0.35	GO:0044446	intracellular organelle part
0.34	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q02083|NAAA_HUMAN
N-acylethanolamine-hydrolyzing acid amidase
Search

NAAA

0.97	N-acylethanolamine-hydrolyzing acid amidase

0.60	GO:0006629	lipid metabolic process
0.38	GO:0000055	ribosomal large subunit export from nucleus
0.37	GO:0042273	ribosomal large subunit biogenesis
0.36	GO:0006470	protein dephosphorylation
0.36	GO:0030036	actin cytoskeleton organization
0.36	GO:0099643	signal release from synapse
0.36	GO:0099531	presynaptic process involved in chemical synaptic transmission
0.36	GO:0006836	neurotransmitter transport
0.35	GO:0001505	regulation of neurotransmitter levels
0.35	GO:0060326	cell chemotaxis

0.51	GO:0008134	transcription factor binding
0.47	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
0.37	GO:0004721	phosphoprotein phosphatase activity
0.36	GO:0005509	calcium ion binding
0.35	GO:0008009	chemokine activity
0.33	GO:0003746	translation elongation factor activity

0.74	GO:0005764	lysosome
0.38	GO:0070062	extracellular exosome
0.37	GO:0005775	vacuolar lumen
0.36	GO:0098793	presynapse
0.30	GO:0031224	intrinsic component of membrane

0.47

EC:3.5

GO:0016810

sp|Q02086|SP2_HUMAN
Transcription factor Sp2
Search

SP2

0.75	Sp2 transcription factor

0.85	GO:0035264	multicellular organism growth
0.51	GO:0000122	negative regulation of transcription by RNA polymerase II
0.49	GO:0048144	fibroblast proliferation
0.45	GO:0001701	in utero embryonic development
0.44	GO:0048568	embryonic organ development
0.44	GO:0072358	cardiovascular system development
0.30	GO:0090304	nucleic acid metabolic process
0.30	GO:0006955	immune response
0.30	GO:0018130	heterocycle biosynthetic process
0.30	GO:1901362	organic cyclic compound biosynthetic process

0.54	GO:0042826	histone deacetylase binding
0.54	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.52	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.30	GO:0043167	ion binding

0.41

GO:0005634

nucleus

sp|Q02094|RHAG_HUMAN
Ammonium transporter Rh type A
Search

RHAG

0.96	Rhesus blood group-associated glycoprotein

0.77	GO:0072488	ammonium transmembrane transport
0.70	GO:0015670	carbon dioxide transport
0.65	GO:0060586	multicellular organismal iron ion homeostasis
0.62	GO:0048821	erythrocyte development
0.59	GO:0006873	cellular ion homeostasis
0.51	GO:0015672	monovalent inorganic cation transport
0.50	GO:0015840	urea transport
0.47	GO:0015695	organic cation transport

0.77	GO:0008519	ammonium transmembrane transporter activity
0.69	GO:0030506	ankyrin binding
0.68	GO:0022842	narrow pore channel activity

0.47	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q02108|GCYA3_HUMAN
Guanylate cyclase soluble subunit alpha-3
Search

GUCY1A3

0.97	Guanylate cyclase soluble subunit alpha-3

0.81	GO:0006182	cGMP biosynthetic process
0.62	GO:0052565	response to defense-related host nitric oxide production
0.61	GO:0035556	intracellular signal transduction
0.61	GO:0030828	positive regulation of cGMP biosynthetic process
0.61	GO:0060087	relaxation of vascular smooth muscle
0.56	GO:0008217	regulation of blood pressure
0.42	GO:0090594	inflammatory response to wounding
0.35	GO:0009635	response to herbicide
0.35	GO:0006171	cAMP biosynthetic process
0.34	GO:0014070	response to organic cyclic compound

0.81	GO:0004383	guanylate cyclase activity
0.60	GO:0020037	heme binding
0.52	GO:1901265	nucleoside phosphate binding
0.50	GO:0036094	small molecule binding
0.47	GO:0004016	adenylate cyclase activity
0.36	GO:0047805	cytidylate cyclase activity
0.35	GO:0097367	carbohydrate derivative binding
0.35	GO:0043168	anion binding
0.34	GO:0005515	protein binding
0.34	GO:0004872	receptor activity

0.62	GO:0008074	guanylate cyclase complex, soluble
0.39	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.81	EC:4.6.1.2	GO:0004383
0.36	KEGG:R00574	GO:0047805

sp|Q02127|PYRD_HUMAN
Dihydroorotate dehydrogenase (quinone), mitochondrial
Search

DHODH

0.49	Dihydroorotate dehydrogenase (quinone), mitochondrial

0.73	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process
0.70	GO:0006222	UMP biosynthetic process
0.52	GO:0055114	oxidation-reduction process
0.40	GO:1903576	response to L-arginine
0.39	GO:0031000	response to caffeine
0.39	GO:0007595	lactation
0.39	GO:0090140	regulation of mitochondrial fission
0.38	GO:0007565	female pregnancy
0.37	GO:0043065	positive regulation of apoptotic process
0.37	GO:0042594	response to starvation

0.77	GO:0004152	dihydroorotate dehydrogenase activity
0.39	GO:0048039	ubiquinone binding
0.36	GO:0010181	FMN binding
0.36	GO:0004252	serine-type endopeptidase activity
0.34	GO:0008144	drug binding
0.33	GO:0005549	odorant binding
0.33	GO:0004984	olfactory receptor activity

0.59	GO:0031966	mitochondrial membrane
0.59	GO:0019866	organelle inner membrane
0.47	GO:0005654	nucleoplasm
0.46	GO:0005829	cytosol
0.38	GO:0043025	neuronal cell body
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.77	EC:1.3.5.2	GO:0004152
0.77	KEGG:R01868	GO:0004152

sp|Q02153|GCYB1_HUMAN
Guanylate cyclase soluble subunit beta-1
Search

GUCY1B3

0.95	Guanylate cyclase soluble subunit beta-1

0.81	GO:0006182	cGMP biosynthetic process
0.61	GO:0035556	intracellular signal transduction
0.56	GO:0099555	trans-synaptic signaling by nitric oxide, modulating synaptic transmission
0.41	GO:0071732	cellular response to nitric oxide
0.36	GO:0006171	cAMP biosynthetic process
0.35	GO:0008015	blood circulation

0.81	GO:0004383	guanylate cyclase activity
0.62	GO:0020037	heme binding
0.51	GO:1901265	nucleoside phosphate binding
0.50	GO:0036094	small molecule binding
0.46	GO:0004016	adenylate cyclase activity
0.40	GO:0047805	cytidylate cyclase activity
0.38	GO:0051879	Hsp90 protein binding
0.36	GO:0046982	protein heterodimerization activity
0.35	GO:0097367	carbohydrate derivative binding
0.35	GO:0046872	metal ion binding

0.49	GO:0008074	guanylate cyclase complex, soluble
0.38	GO:0005886	plasma membrane
0.38	GO:0048786	presynaptic active zone
0.30	GO:0016021	integral component of membrane

0.81	EC:4.6.1.2	GO:0004383
0.40	KEGG:R00574	GO:0047805

sp|Q02156|KPCE_HUMAN
Protein kinase C epsilon type
Search

PRKCE

0.97	Protein kinase C epsilon type

0.63	GO:0006468	protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.61	GO:0035669	TRAM-dependent toll-like receptor 4 signaling pathway
0.61	GO:2001031	positive regulation of cellular glucuronidation
0.59	GO:0010763	positive regulation of fibroblast migration
0.59	GO:0002281	macrophage activation involved in immune response
0.59	GO:0032230	positive regulation of synaptic transmission, GABAergic
0.58	GO:0070257	positive regulation of mucus secretion
0.58	GO:0043278	response to morphine
0.58	GO:0071380	cellular response to prostaglandin E stimulus

0.80	GO:0004697	protein kinase C activity
0.59	GO:0035276	ethanol binding
0.59	GO:0030546	receptor activator activity
0.58	GO:0071889	14-3-3 protein binding
0.56	GO:0003785	actin monomer binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0046872	metal ion binding
0.51	GO:0008047	enzyme activator activity

0.57	GO:0048471	perinuclear region of cytoplasm
0.50	GO:0005794	Golgi apparatus
0.49	GO:0005856	cytoskeleton
0.49	GO:0005783	endoplasmic reticulum
0.48	GO:0005829	cytosol
0.47	GO:0005634	nucleus
0.44	GO:0005739	mitochondrion
0.44	GO:0005886	plasma membrane
0.34	GO:0098588	bounding membrane of organelle
0.34	GO:0031984	organelle subcompartment

0.80

GO:0004697

sp|Q02161|RHD_HUMAN
Blood group Rh(D) polypeptide
Search

RHD

0.88	Rhesus blood group D antigen

0.74	GO:0072488	ammonium transmembrane transport
0.34	GO:0015695	organic cation transport

0.74

GO:0008519

ammonium transmembrane transporter activity

0.33

GO:0005887

integral component of plasma membrane

sp|Q02218|ODO1_HUMAN
2-oxoglutarate dehydrogenase, mitochondrial
Search

OGDH

0.64	Oxoglutarate dehydrogenase

0.71	GO:0006099	tricarboxylic acid cycle
0.58	GO:0018335	protein succinylation
0.56	GO:0006104	succinyl-CoA metabolic process
0.56	GO:0061034	olfactory bulb mitral cell layer development
0.55	GO:0021860	pyramidal neuron development
0.55	GO:0022028	tangential migration from the subventricular zone to the olfactory bulb
0.54	GO:0021794	thalamus development
0.54	GO:0021756	striatum development
0.53	GO:0006103	2-oxoglutarate metabolic process
0.52	GO:0021695	cerebellar cortex development

0.80	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity
0.73	GO:0030976	thiamine pyrophosphate binding
0.56	GO:0034602	oxoglutarate dehydrogenase (NAD+) activity
0.37	GO:0031072	heat shock protein binding
0.37	GO:0051087	chaperone binding
0.35	GO:0046872	metal ion binding

0.54	GO:0045252	oxoglutarate dehydrogenase complex
0.46	GO:0005739	mitochondrion
0.44	GO:0005634	nucleus
0.42	GO:0005829	cytosol
0.38	GO:0043233	organelle lumen
0.36	GO:0044446	intracellular organelle part
0.36	GO:0031090	organelle membrane
0.35	GO:0031975	envelope

0.80	EC:1.2.4.2	GO:0004591
0.56	KEGG:R08549	GO:0034602

sp|Q02221|CX6A2_HUMAN
Cytochrome c oxidase subunit 6A2, mitochondrial
Search

COX6A2

0.81	Cytochrome c oxidase polypeptide VIa-heart

0.62	GO:1902600	hydrogen ion transmembrane transport
0.60	GO:0022900	electron transport chain
0.44	GO:0050790	regulation of catalytic activity
0.42	GO:0006119	oxidative phosphorylation
0.42	GO:0009060	aerobic respiration

0.64	GO:0015002	heme-copper terminal oxidase activity
0.64	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
0.62	GO:0015078	hydrogen ion transmembrane transporter activity
0.61	GO:0009055	electron transfer activity
0.44	GO:0030234	enzyme regulator activity

0.83	GO:0005751	mitochondrial respiratory chain complex IV
0.35	GO:0043209	myelin sheath
0.33	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.64

EC:1.9.3

GO:0016676

sp|Q02223|TNR17_HUMAN
Tumor necrosis factor receptor superfamily member 17
Search

TNFRSF17

0.97	Tumor necrosis factor receptor superfamily member 17

0.71	GO:0002260	lymphocyte homeostasis
0.60	GO:0007165	signal transduction
0.43	GO:0002250	adaptive immune response
0.41	GO:0071356	cellular response to tumor necrosis factor
0.40	GO:0008283	cell proliferation
0.38	GO:0007275	multicellular organism development

0.64

GO:0004872

receptor activity

0.37	GO:0012505	endomembrane system
0.35	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q02224|CENPE_HUMAN
Centromere-associated protein E
Search

CENPE

0.67	centromere-associated protein E

0.74	GO:0007018	microtubule-based movement
0.64	GO:0099607	lateral attachment of mitotic spindle microtubules to kinetochore
0.64	GO:0099606	microtubule plus-end directed mitotic chromosome migration
0.57	GO:0007052	mitotic spindle organization
0.56	GO:0030071	regulation of mitotic metaphase/anaphase transition
0.55	GO:0045860	positive regulation of protein kinase activity
0.40	GO:0051987	positive regulation of attachment of spindle microtubules to kinetochore
0.40	GO:1902101	positive regulation of metaphase/anaphase transition of cell cycle
0.40	GO:1901970	positive regulation of mitotic sister chromatid separation
0.40	GO:0006471	protein ADP-ribosylation

0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.60	GO:0043515	kinetochore binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0016887	ATPase activity
0.39	GO:0003950	NAD+ ADP-ribosyltransferase activity
0.38	GO:0019901	protein kinase binding
0.35	GO:0015299	solute:proton antiporter activity

0.59	GO:0005828	kinetochore microtubule
0.59	GO:1990023	mitotic spindle midzone
0.57	GO:0030496	midbody
0.56	GO:0000779	condensed chromosome, centromeric region
0.55	GO:0000776	kinetochore
0.55	GO:0005871	kinesin complex
0.51	GO:0005654	nucleoplasm
0.50	GO:0005829	cytosol
0.39	GO:0000794	condensed nuclear chromosome
0.38	GO:0044454	nuclear chromosome part

0.45

GO:0016887

sp|Q02241|KIF23_HUMAN
Kinesin-like protein KIF23
Search

KIF23

0.83	Kinesin family member 23

0.85	GO:0072383	plus-end-directed vesicle transport along microtubule
0.85	GO:0044837	actomyosin contractile ring organization
0.85	GO:0000912	assembly of actomyosin apparatus involved in cytokinesis
0.59	GO:0051256	mitotic spindle midzone assembly
0.56	GO:0032467	positive regulation of cytokinesis
0.54	GO:0000281	mitotic cytokinesis

0.75	GO:0003777	microtubule motor activity
0.74	GO:0008017	microtubule binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding

0.60	GO:0097149	centralspindlin complex
0.56	GO:0045171	intercellular bridge
0.55	GO:0030496	midbody
0.53	GO:0005813	centrosome
0.49	GO:0005654	nucleoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q02246|CNTN2_HUMAN
Contactin-2
Search

CNTN2

0.97	LOW QUALITY PROTEIN: contactin-2

0.78	GO:0031175	neuron projection development
0.62	GO:0071206	establishment of protein localization to juxtaparanode region of axon
0.62	GO:0045163	clustering of voltage-gated potassium channels
0.61	GO:0060168	positive regulation of adenosine receptor signaling pathway
0.61	GO:0021853	cerebral cortex GABAergic interneuron migration
0.61	GO:0031133	regulation of axon diameter
0.60	GO:0097090	presynaptic membrane organization
0.59	GO:0022010	central nervous system myelination
0.59	GO:0010954	positive regulation of protein processing
0.59	GO:0048710	regulation of astrocyte differentiation

0.57	GO:0043621	protein self-association
0.50	GO:0030246	carbohydrate binding
0.35	GO:0050839	cell adhesion molecule binding
0.35	GO:0042802	identical protein binding

0.60	GO:0044224	juxtaparanode region of axon
0.60	GO:0033268	node of Ranvier
0.56	GO:0043209	myelin sheath
0.55	GO:0043025	neuronal cell body
0.53	GO:0008076	voltage-gated potassium channel complex
0.52	GO:0009986	cell surface
0.40	GO:0031225	anchored component of membrane
0.36	GO:0045202	synapse

sp|Q02252|MMSA_HUMAN
Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial
Search

ALDH6A1

0.48	Methylmalonate-semialdehyde dehydrogenase

0.58	GO:0019859	thymine metabolic process
0.53	GO:0006208	pyrimidine nucleobase catabolic process
0.53	GO:0006574	valine catabolic process
0.53	GO:0055114	oxidation-reduction process
0.52	GO:0050873	brown fat cell differentiation
0.36	GO:0019484	beta-alanine catabolic process

0.80	GO:0004491	methylmalonate-semialdehyde dehydrogenase (acylating) activity
0.39	GO:0018478	malonate-semialdehyde dehydrogenase (acetylating) activity
0.37	GO:0000062	fatty-acyl-CoA binding
0.34	GO:0016790	thiolester hydrolase activity
0.34	GO:0003723	RNA binding
0.33	GO:0004029	aldehyde dehydrogenase (NAD) activity

0.48	GO:0005654	nucleoplasm
0.44	GO:0005739	mitochondrion
0.36	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.80

EC:1.2.1.27

GO:0004491

sp|Q02297|NRG1_HUMAN
Pro-neuregulin-1, membrane-bound isoform
Search

NRG1

0.96	Pro-neuregulin-1, membrane-bound

0.77	GO:0009790	embryo development
0.55	GO:0021840	directional guidance of interneurons involved in migration from the subpallium to the cortex
0.55	GO:0045213	neurotransmitter receptor metabolic process
0.54	GO:0031643	positive regulation of myelination
0.54	GO:2001223	negative regulation of neuron migration
0.54	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade
0.53	GO:0003161	cardiac conduction system development
0.53	GO:2000010	positive regulation of protein localization to cell surface
0.53	GO:0021781	glial cell fate commitment
0.53	GO:0038129	ERBB3 signaling pathway

0.73	GO:0005102	receptor binding
0.49	GO:0003712	transcription cofactor activity
0.48	GO:0050839	cell adhesion molecule binding
0.48	GO:0030545	receptor regulator activity
0.46	GO:0032403	protein complex binding
0.45	GO:1990782	protein tyrosine kinase binding
0.36	GO:0030296	protein tyrosine kinase activator activity
0.36	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity
0.35	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.35	GO:0004713	protein tyrosine kinase activity

0.53	GO:0030673	axolemma
0.51	GO:0031594	neuromuscular junction
0.50	GO:0009897	external side of plasma membrane
0.50	GO:0030425	dendrite
0.50	GO:0044297	cell body
0.46	GO:0005576	extracellular region
0.44	GO:0005654	nucleoplasm
0.44	GO:0005887	integral component of plasma membrane
0.37	GO:0005737	cytoplasm
0.36	GO:0016324	apical plasma membrane

0.36	EC:2.7.1.153	GO:0046934
0.36	KEGG:R04545	GO:0046934

sp|Q02318|CP27A_HUMAN
Sterol 26-hydroxylase, mitochondrial
Search

CYP27A1

0.93	Thromboxane-A synthase

0.53	GO:0055114	oxidation-reduction process
0.37	GO:0016125	sterol metabolic process
0.37	GO:0006694	steroid biosynthetic process
0.36	GO:0008206	bile acid metabolic process
0.36	GO:1901617	organic hydroxy compound biosynthetic process
0.36	GO:0070640	vitamin D3 metabolic process
0.36	GO:0042362	fat-soluble vitamin biosynthetic process
0.35	GO:0006706	steroid catabolic process
0.35	GO:0044107	cellular alcohol metabolic process
0.35	GO:0042446	hormone biosynthetic process

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.66	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.36	GO:0030343	vitamin D3 25-hydroxylase activity
0.33	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.45	GO:0031966	mitochondrial membrane
0.45	GO:0019866	organelle inner membrane
0.35	GO:0005759	mitochondrial matrix
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

sp|Q02325|PLGB_HUMAN
Plasminogen-like protein B
Search

0.89	Plasminogen-like protein B

0.66

GO:0005576

extracellular region

sp|Q02338|BDH_HUMAN
D-beta-hydroxybutyrate dehydrogenase, mitochondrial
Search

BDH1

0.48	D-beta-hydroxybutyrate dehydrogenase

0.52	GO:0055114	oxidation-reduction process
0.36	GO:0046951	ketone body biosynthetic process
0.36	GO:0051412	response to corticosterone
0.35	GO:0060612	adipose tissue development
0.35	GO:0060416	response to growth hormone
0.35	GO:0046952	ketone body catabolic process
0.35	GO:0032355	response to estradiol
0.35	GO:0045471	response to ethanol
0.35	GO:0001889	liver development
0.35	GO:0046686	response to cadmium ion

0.54	GO:0003858	3-hydroxybutyrate dehydrogenase activity
0.34	GO:0005543	phospholipid binding

0.48	GO:0005654	nucleoplasm
0.45	GO:0005739	mitochondrion
0.44	GO:0019866	organelle inner membrane
0.42	GO:0098576	lumenal side of membrane
0.30	GO:0031224	intrinsic component of membrane

0.54	EC:1.1.1.30	GO:0003858
0.54	KEGG:R01361	GO:0003858

sp|Q02363|ID2_HUMAN
DNA-binding protein inhibitor ID-2
Search

ID2

0.97	Inhibitor of DNA binding 2, dominant negative helix-loop-helix protein, a

0.72	GO:0045892	negative regulation of transcription, DNA-templated
0.59	GO:0061031	endodermal digestive tract morphogenesis
0.57	GO:0045578	negative regulation of B cell differentiation
0.57	GO:0045777	positive regulation of blood pressure
0.57	GO:0003166	bundle of His development
0.57	GO:0048557	embryonic digestive tract morphogenesis
0.57	GO:0090398	cellular senescence
0.57	GO:2000178	negative regulation of neural precursor cell proliferation
0.57	GO:0001966	thigmotaxis
0.56	GO:0071158	positive regulation of cell cycle arrest

0.68	GO:0046983	protein dimerization activity
0.55	GO:0044325	ion channel binding
0.47	GO:0003677	DNA binding
0.39	GO:0043425	bHLH transcription factor binding
0.34	GO:1901707	leptomycin B binding
0.33	GO:0003700	DNA binding transcription factor activity
0.33	GO:0019904	protein domain specific binding

0.61	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.44	GO:0043234	protein complex
0.34	GO:0000785	chromatin

sp|Q02383|SEMG2_HUMAN
Semenogelin-2
Search

0.73	Semenogelin-2

0.87	GO:1901318	negative regulation of flagellated sperm motility
0.82	GO:0050817	coagulation
0.39	GO:1900005	positive regulation of serine-type endopeptidase activity
0.38	GO:0019731	antibacterial humoral response
0.37	GO:0051291	protein heterooligomerization

0.37	GO:0002020	protease binding
0.33	GO:0046872	metal ion binding

0.66	GO:0005576	extracellular region
0.30	GO:0044464	cell part
0.30	GO:0043226	organelle

sp|Q02386|ZNF45_HUMAN
Zinc finger protein 45
Search

0.62	Zinc finger protein 45

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.36	GO:0006351	transcription, DNA-templated
0.33	GO:1902679	negative regulation of RNA biosynthetic process
0.30	GO:0007275	multicellular organism development

0.51	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.42	GO:0003700	DNA binding transcription factor activity
0.35	GO:0032550	purine ribonucleoside binding
0.35	GO:0019001	guanyl nucleotide binding
0.35	GO:0005515	protein binding
0.34	GO:0032555	purine ribonucleotide binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding

0.44	GO:0005622	intracellular
0.36	GO:0043227	membrane-bounded organelle
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044422	organelle part
0.30	GO:0016020	membrane

sp|Q02388|CO7A1_HUMAN
Collagen alpha-1(VII) chain
Search

COL7A1

0.83	Collagen type VII alpha 1 chain

0.70	GO:0010951	negative regulation of endopeptidase activity
0.59	GO:0035987	endodermal cell differentiation
0.38	GO:0007155	cell adhesion
0.37	GO:0030198	extracellular matrix organization
0.36	GO:0010469	regulation of receptor activity
0.35	GO:0007586	digestion
0.35	GO:0048589	developmental growth
0.35	GO:0048468	cell development
0.35	GO:0030574	collagen catabolic process
0.35	GO:0048731	system development

0.72	GO:0004867	serine-type endopeptidase inhibitor activity
0.52	GO:0042802	identical protein binding
0.47	GO:0005201	extracellular matrix structural constituent
0.37	GO:0005179	hormone activity
0.36	GO:0051431	corticotropin-releasing hormone receptor 2 binding
0.32	GO:0004930	G-protein coupled receptor activity
0.32	GO:0046872	metal ion binding
0.31	GO:0003723	RNA binding
0.30	GO:0003824	catalytic activity

0.63	GO:0005581	collagen trimer
0.60	GO:0005604	basement membrane
0.37	GO:0098644	complex of collagen trimers
0.37	GO:0005615	extracellular space
0.35	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane
0.35	GO:0005788	endoplasmic reticulum lumen
0.34	GO:0099081	supramolecular polymer
0.34	GO:0030134	COPII-coated ER to Golgi transport vesicle
0.34	GO:0000139	Golgi membrane
0.30	GO:0016021	integral component of membrane

sp|Q02410|APBA1_HUMAN
Amyloid beta A4 precursor protein-binding family A member 1
Search

APBA1

0.97	Amyloid beta precursor protein binding family A member 1

0.77	GO:0007268	chemical synaptic transmission
0.66	GO:0006461	protein complex assembly
0.60	GO:0014051	gamma-aminobutyric acid secretion
0.59	GO:0014047	glutamate secretion
0.57	GO:0035264	multicellular organism growth
0.55	GO:0007626	locomotory behavior
0.52	GO:0001701	in utero embryonic development
0.49	GO:0006886	intracellular protein transport
0.43	GO:0060255	regulation of macromolecule metabolic process
0.37	GO:0099643	signal release from synapse

0.85	GO:0001540	amyloid-beta binding
0.36	GO:0005515	protein binding
0.35	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
0.34	GO:0044877	macromolecular complex binding

0.81	GO:0008021	synaptic vesicle
0.50	GO:0005794	Golgi apparatus
0.38	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0043005	neuron projection
0.35	GO:0005829	cytosol
0.35	GO:0005634	nucleus
0.35	GO:0036477	somatodendritic compartment
0.35	GO:0098794	postsynapse
0.35	GO:0120038	plasma membrane bounded cell projection part
0.33	GO:0043234	protein complex

sp|Q02413|DSG1_HUMAN
Desmoglein-1
Search

DSG1

0.91	Desmoglein-1-alpha

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.54	GO:0030216	keratinocyte differentiation
0.54	GO:0001942	hair follicle development
0.53	GO:0030509	BMP signaling pathway
0.52	GO:0050821	protein stabilization
0.37	GO:0003165	Purkinje myocyte development
0.37	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication
0.36	GO:0098911	regulation of ventricular cardiac muscle cell action potential
0.36	GO:0002934	desmosome organization
0.36	GO:0086091	regulation of heart rate by cardiac conduction

0.70	GO:0005509	calcium ion binding
0.58	GO:0045295	gamma-catenin binding
0.35	GO:0050839	cell adhesion molecule binding
0.32	GO:0015643	toxic substance binding

0.60	GO:0005911	cell-cell junction
0.55	GO:0005886	plasma membrane
0.54	GO:0070161	anchoring junction
0.51	GO:0098562	cytoplasmic side of membrane
0.38	GO:0044421	extracellular region part
0.36	GO:0031982	vesicle
0.35	GO:0045177	apical part of cell
0.34	GO:0005829	cytosol
0.33	GO:0043231	intracellular membrane-bounded organelle
0.32	GO:0098805	whole membrane

sp|Q02446|SP4_HUMAN
Transcription factor Sp4
Search

SP4

0.95	Trans-acting transcription factor 4

0.69	GO:0006357	regulation of transcription by RNA polymerase II
0.38	GO:0007018	microtubule-based movement
0.38	GO:0008016	regulation of heart contraction
0.34	GO:0006351	transcription, DNA-templated

0.77	GO:0003713	transcription coactivator activity
0.60	GO:0003700	DNA binding transcription factor activity
0.50	GO:0003676	nucleic acid binding
0.38	GO:0003777	microtubule motor activity
0.36	GO:0016887	ATPase activity
0.35	GO:0032559	adenyl ribonucleotide binding
0.34	GO:0008144	drug binding
0.34	GO:0035639	purine ribonucleoside triphosphate binding
0.34	GO:0046872	metal ion binding
0.34	GO:0005515	protein binding

0.60	GO:0005634	nucleus
0.50	GO:0005829	cytosol
0.49	GO:0031974	membrane-enclosed lumen
0.45	GO:0044446	intracellular organelle part
0.37	GO:0015630	microtubule cytoskeleton
0.36	GO:1902494	catalytic complex
0.35	GO:0043234	protein complex
0.30	GO:0031224	intrinsic component of membrane

0.36

GO:0016887

sp|Q02447|SP3_HUMAN
Transcription factor Sp3
Search

SP3

0.96	Transcription factor Sp3

0.59	GO:0043353	enucleate erythrocyte differentiation
0.58	GO:0001779	natural killer cell differentiation
0.58	GO:1903131	mononuclear cell differentiation
0.57	GO:0030219	megakaryocyte differentiation
0.57	GO:0030851	granulocyte differentiation
0.57	GO:0060216	definitive hemopoiesis
0.57	GO:0048596	embryonic camera-type eye morphogenesis
0.56	GO:0030183	B cell differentiation
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:1903506	regulation of nucleic acid-templated transcription

0.77	GO:0000987	proximal promoter sequence-specific DNA binding
0.60	GO:0003700	DNA binding transcription factor activity
0.53	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.52	GO:0003682	chromatin binding
0.36	GO:0005515	protein binding
0.34	GO:0046872	metal ion binding

0.60	GO:0005634	nucleus
0.54	GO:0017053	transcriptional repressor complex
0.37	GO:0032993	protein-DNA complex
0.36	GO:0031974	membrane-enclosed lumen
0.35	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|Q02487|DSC2_HUMAN
Desmocollin-2
Search

DSC2

0.97	Desmocollin-2

0.78	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
0.57	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication
0.56	GO:0098911	regulation of ventricular cardiac muscle cell action potential
0.55	GO:0086091	regulation of heart rate by cardiac conduction
0.51	GO:0009267	cellular response to starvation
0.38	GO:0070268	cornification
0.38	GO:0050821	protein stabilization
0.37	GO:0001701	in utero embryonic development
0.34	GO:0043312	neutrophil degranulation
0.34	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules

0.70	GO:0005509	calcium ion binding
0.39	GO:0045295	gamma-catenin binding
0.37	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication

0.58	GO:0030057	desmosome
0.56	GO:0005886	plasma membrane
0.55	GO:0014704	intercalated disc
0.53	GO:0005913	cell-cell adherens junction
0.49	GO:0031410	cytoplasmic vesicle
0.40	GO:0070062	extracellular exosome
0.34	GO:0005921	gap junction
0.33	GO:0012506	vesicle membrane
0.33	GO:0098805	whole membrane
0.33	GO:0098588	bounding membrane of organelle

sp|Q02505|MUC3A_HUMAN
Mucin-3A
Search

MUC3A

0.86	Mucin 3A, cell surface associated

0.61	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.58	GO:0016266	O-glycan processing
0.35	GO:0033189	response to vitamin A
0.34	GO:0006508	proteolysis
0.34	GO:0009725	response to hormone
0.33	GO:0009405	pathogenesis
0.32	GO:0006030	chitin metabolic process
0.32	GO:1903506	regulation of nucleic acid-templated transcription

0.61	GO:0030197	extracellular matrix constituent, lubricant activity
0.34	GO:0070011	peptidase activity, acting on L-amino acid peptides
0.33	GO:0042393	histone binding
0.33	GO:0046982	protein heterodimerization activity
0.33	GO:0003713	transcription coactivator activity
0.33	GO:0005509	calcium ion binding
0.32	GO:0008061	chitin binding

0.59	GO:0005796	Golgi lumen
0.47	GO:0005576	extracellular region
0.43	GO:0005886	plasma membrane
0.34	GO:0005902	microvillus
0.34	GO:0045177	apical part of cell
0.32	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|Q02509|OC90_HUMAN
Otoconin-90
Search

OC90

0.43	Phospholipase A(2)

0.82	GO:1903963	arachidonate transport
0.82	GO:0032309	icosanoid secretion
0.72	GO:0016042	lipid catabolic process
0.67	GO:0006644	phospholipid metabolic process
0.37	GO:0009405	pathogenesis
0.33	GO:0044179	hemolysis in other organism

0.81	GO:0004623	phospholipase A2 activity
0.70	GO:0005509	calcium ion binding
0.53	GO:0102567	phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)
0.53	GO:0102568	phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)
0.50	GO:0005198	structural molecule activity
0.37	GO:0090729	toxin activity

0.66	GO:0005576	extracellular region
0.30	GO:0031224	intrinsic component of membrane

0.81

EC:3.1.1.4

GO:0004623

sp|Q02535|ID3_HUMAN
DNA-binding protein inhibitor ID-3
Search

ID3

0.97	DNA-binding protein inhibitor ID-3-A

0.71	GO:0045892	negative regulation of transcription, DNA-templated
0.66	GO:0072750	cellular response to leptomycin B
0.62	GO:0045667	regulation of osteoblast differentiation
0.62	GO:0045662	negative regulation of myoblast differentiation
0.61	GO:0030903	notochord development
0.61	GO:0048511	rhythmic process
0.60	GO:0030279	negative regulation of ossification
0.60	GO:0001656	metanephros development
0.60	GO:0043433	negative regulation of DNA binding transcription factor activity
0.59	GO:0042476	odontogenesis

0.68	GO:0046983	protein dimerization activity
0.66	GO:1901707	leptomycin B binding
0.56	GO:0008134	transcription factor binding
0.55	GO:0019904	protein domain specific binding
0.47	GO:0003700	DNA binding transcription factor activity
0.45	GO:0003677	DNA binding
0.36	GO:0003714	transcription corepressor activity
0.34	GO:0008113	peptide-methionine (S)-S-oxide reductase activity
0.34	GO:0003682	chromatin binding

0.61	GO:0005634	nucleus
0.49	GO:0005737	cytoplasm
0.33	GO:0043234	protein complex

0.34

EC:1.8.4 EC:1.8.4.11

GO:0008113

sp|Q02539|H11_HUMAN
Histone H1.1
Search

0.97	Histone cluster 1 H1 family member a

0.79	GO:0006334	nucleosome assembly
0.56	GO:0098532	histone H3-K27 trimethylation
0.54	GO:0080182	histone H3-K4 trimethylation
0.53	GO:0016584	nucleosome positioning
0.53	GO:0000122	negative regulation of transcription by RNA polymerase II
0.47	GO:0051130	positive regulation of cellular component organization
0.46	GO:0071169	establishment of protein localization to chromatin
0.46	GO:0048259	regulation of receptor-mediated endocytosis
0.45	GO:0051570	regulation of histone H3-K9 methylation
0.44	GO:0007283	spermatogenesis

0.65	GO:0031490	chromatin DNA binding
0.45	GO:0008201	heparin binding
0.44	GO:0042826	histone deacetylase binding
0.40	GO:0032564	dATP binding
0.38	GO:0016208	AMP binding
0.37	GO:0043531	ADP binding
0.37	GO:0003690	double-stranded DNA binding
0.36	GO:0005509	calcium ion binding
0.36	GO:0003723	RNA binding
0.36	GO:0032550	purine ribonucleoside binding

0.75	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.58	GO:0000791	euchromatin
0.55	GO:0031974	membrane-enclosed lumen
0.51	GO:0000792	heterochromatin
0.47	GO:0035327	transcriptionally active chromatin
0.43	GO:0031982	vesicle
0.43	GO:0009986	cell surface
0.37	GO:0043230	extracellular organelle
0.36	GO:0005615	extracellular space

sp|Q02543|RL18A_HUMAN
60S ribosomal protein L18a
Search

0.63	Ribosomal protein L18a variant (Fragment)

0.59	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.38	GO:0097327	response to antineoplastic agent
0.34	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.33	GO:0016072	rRNA metabolic process
0.33	GO:0042254	ribosome biogenesis

0.63	GO:0003735	structural constituent of ribosome
0.41	GO:0003723	RNA binding
0.34	GO:0005515	protein binding

0.61	GO:0005840	ribosome
0.50	GO:0044445	cytosolic part
0.49	GO:0005844	polysome
0.43	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|Q02548|PAX5_HUMAN
Paired box protein Pax-5
Search

PAX5

0.95	LOW QUALITY PROTEIN: paired box protein Pax-5

0.69	GO:0007275	multicellular organism development
0.62	GO:0051573	negative regulation of histone H3-K9 methylation
0.59	GO:1904888	cranial skeletal system development
0.58	GO:0030534	adult behavior
0.57	GO:0014706	striated muscle tissue development
0.57	GO:0006351	transcription, DNA-templated
0.57	GO:0007568	aging
0.57	GO:0060322	head development
0.57	GO:0061061	muscle structure development
0.56	GO:2001141	regulation of RNA biosynthetic process

0.58	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.57	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.35	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.52	GO:0005829	cytosol
0.51	GO:0031974	membrane-enclosed lumen
0.46	GO:0043232	intracellular non-membrane-bounded organelle
0.45	GO:0044446	intracellular organelle part
0.35	GO:0005667	transcription factor complex

sp|Q02556|IRF8_HUMAN
Interferon regulatory factor 8
Search

IRF8

0.97	Interferon regulatory factor 8

0.60	GO:0044130	negative regulation of growth of symbiont in host
0.60	GO:0042832	defense response to protozoan
0.59	GO:0032735	positive regulation of interleukin-12 production
0.59	GO:0030099	myeloid cell differentiation
0.58	GO:0032729	positive regulation of interferon-gamma production
0.58	GO:0071346	cellular response to interferon-gamma
0.58	GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter
0.57	GO:0006351	transcription, DNA-templated
0.57	GO:0071222	cellular response to lipopolysaccharide
0.57	GO:0006909	phagocytosis

0.75	GO:0044212	transcription regulatory region DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.53	GO:1990837	sequence-specific double-stranded DNA binding
0.37	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
0.36	GO:0004725	protein tyrosine phosphatase activity
0.36	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.49	GO:0031974	membrane-enclosed lumen
0.44	GO:0044446	intracellular organelle part
0.39	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

0.37

GO:0008138

sp|Q02575|HEN1_HUMAN
Helix-loop-helix protein 1
Search

NHLH1

0.97	Nescient helix loop helix 1

0.55	GO:0006366	transcription by RNA polymerase II
0.55	GO:0045944	positive regulation of transcription by RNA polymerase II
0.48	GO:0007617	mating behavior
0.48	GO:0042698	ovulation cycle
0.37	GO:0030154	cell differentiation
0.37	GO:0007275	multicellular organism development
0.34	GO:0051091	positive regulation of DNA binding transcription factor activity

0.68	GO:0046983	protein dimerization activity
0.58	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.58	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.49	GO:0001102	RNA polymerase II activating transcription factor binding
0.46	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.46	GO:0000987	proximal promoter sequence-specific DNA binding
0.32	GO:0030554	adenyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0008144	drug binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.42	GO:0005634	nucleus
0.33	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

sp|Q02577|HEN2_HUMAN
Helix-loop-helix protein 2
Search

NHLH2

0.97	Nescient helix-loop-helix 2

0.56	GO:0006366	transcription by RNA polymerase II
0.55	GO:0045944	positive regulation of transcription by RNA polymerase II
0.55	GO:0007617	mating behavior
0.54	GO:0042698	ovulation cycle
0.37	GO:0030154	cell differentiation
0.37	GO:0007275	multicellular organism development
0.35	GO:0051091	positive regulation of DNA binding transcription factor activity

0.68	GO:0046983	protein dimerization activity
0.59	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.58	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.55	GO:0001102	RNA polymerase II activating transcription factor binding
0.52	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.52	GO:0000987	proximal promoter sequence-specific DNA binding

0.42	GO:0005634	nucleus
0.34	GO:0005667	transcription factor complex
0.30	GO:0016020	membrane

sp|Q02641|CACB1_HUMAN
Voltage-dependent L-type calcium channel subunit beta-1
Search

CACNB1

0.83	Voltage-dependent L-type calcium channel subunit beta-1

0.77	GO:0070588	calcium ion transmembrane transport
0.57	GO:1902514	regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
0.55	GO:1904646	cellular response to amyloid-beta
0.52	GO:1901385	regulation of voltage-gated calcium channel activity
0.51	GO:0007528	neuromuscular junction development
0.48	GO:0007268	chemical synaptic transmission
0.47	GO:0070978	voltage-gated calcium channel complex assembly
0.43	GO:0006936	muscle contraction
0.38	GO:0006612	protein targeting to membrane
0.37	GO:0061337	cardiac conduction

0.82	GO:0005245	voltage-gated calcium channel activity
0.39	GO:0005515	protein binding

0.81	GO:0005891	voltage-gated calcium channel complex
0.44	GO:0042383	sarcolemma
0.40	GO:0016529	sarcoplasmic reticulum

sp|Q02643|GHRHR_HUMAN
Growth hormone-releasing hormone receptor
Search

GHRHR

0.97	Pituitary growth hormone-releasing hormone receptor

0.69	GO:0007166	cell surface receptor signaling pathway
0.69	GO:0007186	G-protein coupled receptor signaling pathway
0.59	GO:0060133	somatotropin secreting cell development
0.58	GO:0030252	growth hormone secretion
0.58	GO:0060124	positive regulation of growth hormone secretion
0.57	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway
0.56	GO:0040018	positive regulation of multicellular organism growth
0.56	GO:0030104	water homeostasis
0.56	GO:0043627	response to estrogen
0.56	GO:0033143	regulation of intracellular steroid hormone receptor signaling pathway

0.70	GO:0004930	G-protein coupled receptor activity
0.57	GO:0017046	peptide hormone binding
0.54	GO:0019838	growth factor binding

0.56	GO:0005640	nuclear outer membrane
0.55	GO:0016363	nuclear matrix
0.54	GO:0005637	nuclear inner membrane
0.53	GO:0030141	secretory granule
0.51	GO:0009986	cell surface
0.50	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q02742|GCNT1_HUMAN
Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase
Search

GCNT1

0.94	Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase

0.62	GO:0060352	cell adhesion molecule production
0.61	GO:0060993	kidney morphogenesis
0.60	GO:0050901	leukocyte tethering or rolling
0.57	GO:0048729	tissue morphogenesis
0.54	GO:0009101	glycoprotein biosynthetic process
0.49	GO:0002426	immunoglobulin production in mucosal tissue
0.47	GO:0050892	intestinal absorption
0.42	GO:0043413	macromolecule glycosylation
0.38	GO:0036211	protein modification process
0.38	GO:0032868	response to insulin

0.77	GO:0008375	acetylglucosaminyltransferase activity
0.51	GO:0140103	catalytic activity, acting on a glycoprotein
0.33	GO:0005515	protein binding

0.55	GO:0031985	Golgi cisterna
0.55	GO:0005802	trans-Golgi network
0.41	GO:0000139	Golgi membrane
0.38	GO:0005615	extracellular space
0.37	GO:0044178	host cell Golgi membrane
0.35	GO:1903561	extracellular vesicle
0.30	GO:0031224	intrinsic component of membrane

0.77

GO:0008375

sp|Q02747|GUC2A_HUMAN
Guanylin
Search

GUCA2A

0.96	Guanylate cyclase activator 2A

0.86	GO:0031284	positive regulation of guanylate cyclase activity
0.39	GO:0007586	digestion
0.38	GO:0010469	regulation of receptor activity
0.35	GO:0045776	negative regulation of blood pressure
0.35	GO:0007588	excretion
0.35	GO:0007589	body fluid secretion
0.35	GO:0006182	cGMP biosynthetic process

0.86	GO:0010853	cyclase activator activity
0.86	GO:0030249	guanylate cyclase regulator activity
0.75	GO:0008047	enzyme activator activity
0.38	GO:0005179	hormone activity

0.66	GO:0005576	extracellular region
0.39	GO:0031982	vesicle
0.35	GO:0001750	photoreceptor outer segment

sp|Q02750|MP2K1_HUMAN
Dual specificity mitogen-activated protein kinase kinase 1
Search

MAP2K1

0.87	Dual specificity mitogen-activated protein kinase kinase 1

0.63	GO:0006468	protein phosphorylation
0.57	GO:0060502	epithelial cell proliferation involved in lung morphogenesis
0.56	GO:0060440	trachea formation
0.55	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA
0.55	GO:0030878	thyroid gland development
0.54	GO:0048679	regulation of axon regeneration
0.54	GO:0090398	cellular senescence
0.54	GO:0048538	thymus development
0.54	GO:0060324	face development
0.54	GO:0060020	Bergmann glial cell differentiation

0.69	GO:0004674	protein serine/threonine kinase activity
0.56	GO:0004728	signal transducer, downstream of receptor, with protein tyrosine phosphatase activity
0.55	GO:0030554	adenyl nucleotide binding
0.55	GO:0004708	MAP kinase kinase activity
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0097110	scaffold protein binding
0.53	GO:0047485	protein N-terminus binding
0.53	GO:0043539	protein serine/threonine kinase activator activity

0.47	GO:0005783	endoplasmic reticulum
0.46	GO:0005829	cytosol
0.41	GO:0005886	plasma membrane
0.40	GO:0005815	microtubule organizing center
0.37	GO:0005925	focal adhesion
0.37	GO:0005770	late endosome
0.37	GO:0005769	early endosome
0.37	GO:0005634	nucleus
0.36	GO:0070062	extracellular exosome
0.36	GO:0005794	Golgi apparatus

0.69

GO:0004674

sp|Q02763|TIE2_HUMAN
Angiopoietin-1 receptor
Search

TEK

0.67	Endothelial-specific receptor tyrosine kinase

0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.71	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.59	GO:0016525	negative regulation of angiogenesis
0.58	GO:2000251	positive regulation of actin cytoskeleton reorganization
0.58	GO:0051894	positive regulation of focal adhesion assembly
0.57	GO:0001568	blood vessel development
0.57	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity
0.57	GO:0030334	regulation of cell migration
0.56	GO:0034446	substrate adhesion-dependent cell spreading
0.56	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling

0.77	GO:0004713	protein tyrosine kinase activity
0.74	GO:0019199	transmembrane receptor protein kinase activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.39	GO:0019838	growth factor binding
0.35	GO:0005088	Ras guanyl-nucleotide exchange factor activity
0.35	GO:0005057	signal transducer activity, downstream of receptor
0.35	GO:0005509	calcium ion binding

0.61	GO:0005887	integral component of plasma membrane
0.57	GO:0009925	basal plasma membrane
0.56	GO:0097517	contractile actin filament bundle
0.56	GO:0005902	microvillus
0.56	GO:0042641	actomyosin
0.55	GO:0005884	actin filament
0.54	GO:0016324	apical plasma membrane
0.54	GO:0098857	membrane microdomain
0.52	GO:0005911	cell-cell junction
0.51	GO:0009986	cell surface

0.77

GO:0004713

sp|Q02779|M3K10_HUMAN
Mitogen-activated protein kinase kinase kinase 10
Search

MAP3K10

0.82	Mitogen-activated protein kinase kinase kinase

0.82	GO:0000186	activation of MAPKK activity
0.78	GO:0000165	MAPK cascade
0.77	GO:0043507	positive regulation of JUN kinase activity
0.75	GO:0031098	stress-activated protein kinase signaling cascade
0.52	GO:0018107	peptidyl-threonine phosphorylation
0.52	GO:0043433	negative regulation of DNA binding transcription factor activity
0.52	GO:0007224	smoothened signaling pathway
0.51	GO:0018105	peptidyl-serine phosphorylation
0.51	GO:0000187	activation of MAPK activity
0.48	GO:0045892	negative regulation of transcription, DNA-templated

0.83	GO:0004709	MAP kinase kinase kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0043425	bHLH transcription factor binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0003714	transcription corepressor activity
0.37	GO:0042803	protein homodimerization activity
0.35	GO:0031624	ubiquitin conjugating enzyme binding
0.35	GO:0048365	Rac GTPase binding
0.34	GO:0019900	kinase binding

0.45

GO:0005622

intracellular

0.83

EC:2.7.11 EC:2.7.11.25

GO:0004709

sp|Q02790|FKBP4_HUMAN
Peptidyl-prolyl cis-trans isomerase FKBP4
Search

FKBP4

0.51	Peptidyl-prolyl cis-trans isomerase FKBP4

0.86	GO:0006463	steroid hormone receptor complex assembly
0.85	GO:0031111	negative regulation of microtubule polymerization or depolymerization
0.84	GO:0010977	negative regulation of neuron projection development
0.82	GO:0007566	embryo implantation
0.82	GO:0030521	androgen receptor signaling pathway
0.82	GO:0030850	prostate gland development
0.78	GO:0061077	chaperone-mediated protein folding
0.78	GO:0046661	male sex differentiation
0.76	GO:0031503	protein complex localization
0.73	GO:0031113	regulation of microtubule polymerization

0.85	GO:0005528	FK506 binding
0.85	GO:0048156	tau protein binding
0.85	GO:0035259	glucocorticoid receptor binding
0.80	GO:0032767	copper-dependent protein binding
0.78	GO:0051219	phosphoprotein binding
0.78	GO:0031072	heat shock protein binding
0.72	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
0.62	GO:0032550	purine ribonucleoside binding
0.62	GO:0019001	guanyl nucleotide binding
0.53	GO:0030674	protein binding, bridging

0.86	GO:0044295	axonal growth cone
0.73	GO:0005874	microtubule
0.70	GO:0043025	neuronal cell body
0.68	GO:0005829	cytosol
0.68	GO:0048471	perinuclear region of cytoplasm
0.66	GO:0005654	nucleoplasm
0.63	GO:0070062	extracellular exosome
0.60	GO:0005739	mitochondrion
0.53	GO:0043234	protein complex

0.72

GO:0003755

sp|Q02809|PLOD1_HUMAN
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1
Search

PLOD1

0.97	LOW QUALITY PROTEIN: procollagen-lysine,2-oxoglutarate 5-dioxygenase 1

0.61	GO:0046947	hydroxylysine biosynthetic process
0.61	GO:0017185	peptidyl-lysine hydroxylation
0.55	GO:0008544	epidermis development
0.53	GO:0001666	response to hypoxia
0.52	GO:0055114	oxidation-reduction process
0.45	GO:0033334	fin morphogenesis
0.42	GO:0001886	endothelial cell morphogenesis
0.42	GO:0006493	protein O-linked glycosylation
0.42	GO:0070831	basement membrane assembly
0.42	GO:0042311	vasodilation

0.86	GO:0008475	procollagen-lysine 5-dioxygenase activity
0.77	GO:0031418	L-ascorbic acid binding
0.62	GO:0005506	iron ion binding
0.46	GO:0033823	procollagen glucosyltransferase activity
0.34	GO:0042277	peptide binding
0.34	GO:0005515	protein binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0032561	guanyl ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.69	GO:0005783	endoplasmic reticulum
0.44	GO:1902494	catalytic complex
0.41	GO:0031984	organelle subcompartment
0.40	GO:0044421	extracellular region part
0.39	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.39	GO:0005581	collagen trimer
0.39	GO:0005794	Golgi apparatus
0.39	GO:0098588	bounding membrane of organelle
0.36	GO:0031982	vesicle
0.30	GO:0031224	intrinsic component of membrane

0.86

EC:1.14.11.4

GO:0008475

sp|Q02817|MUC2_HUMAN
Mucin-2
Search

0.46

Mucin-2

0.49	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.47	GO:0030277	maintenance of gastrointestinal epithelium
0.47	GO:0016266	O-glycan processing
0.38	GO:0010466	negative regulation of peptidase activity
0.35	GO:0048015	phosphatidylinositol-mediated signaling
0.34	GO:0006979	response to oxidative stress
0.34	GO:0098869	cellular oxidant detoxification
0.33	GO:0006096	glycolytic process
0.32	GO:0055114	oxidation-reduction process
0.32	GO:0030336	negative regulation of cell migration

0.40	GO:0005515	protein binding
0.38	GO:0030414	peptidase inhibitor activity
0.36	GO:0005201	extracellular matrix structural constituent
0.34	GO:0004601	peroxidase activity
0.33	GO:0020037	heme binding
0.33	GO:0004634	phosphopyruvate hydratase activity
0.32	GO:0000287	magnesium ion binding

0.85	GO:0070701	mucus layer
0.48	GO:0005796	Golgi lumen
0.38	GO:0005886	plasma membrane
0.35	GO:0070062	extracellular exosome
0.33	GO:0000015	phosphopyruvate hydratase complex
0.32	GO:0005578	proteinaceous extracellular matrix
0.30	GO:0016021	integral component of membrane

0.34	EC:1.11.1.7	GO:0004601
0.34	KEGG:R03532	GO:0004601

sp|Q02818|NUCB1_HUMAN
Nucleobindin-1
Search

NUCB1

0.89	Nucleobindin-1

0.40	GO:0072718	response to cisplatin
0.39	GO:1903533	regulation of protein targeting
0.35	GO:0043687	post-translational protein modification
0.32	GO:0055114	oxidation-reduction process

0.69	GO:0005509	calcium ion binding
0.39	GO:0001965	G-protein alpha-subunit binding
0.35	GO:0003677	DNA binding
0.32	GO:0016491	oxidoreductase activity

0.53	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment
0.45	GO:0005640	nuclear outer membrane
0.42	GO:0005783	endoplasmic reticulum
0.41	GO:0098547	lumenal side of Golgi membrane
0.39	GO:0090498	extrinsic component of Golgi membrane
0.38	GO:0005801	cis-Golgi network
0.38	GO:0032580	Golgi cisterna membrane
0.38	GO:0005769	early endosome
0.38	GO:0005802	trans-Golgi network
0.37	GO:0005576	extracellular region

0.32

GO:0016491

sp|Q02833|RASF7_HUMAN
Ras association domain-containing protein 7
Search

RASSF7

0.88	Ras association domain-containing protein 7

0.74	GO:0070507	regulation of microtubule cytoskeleton organization
0.60	GO:0007165	signal transduction
0.58	GO:0034334	adherens junction maintenance
0.37	GO:0006915	apoptotic process

0.34	GO:0005515	protein binding
0.33	GO:0046872	metal ion binding

0.52	GO:0005815	microtubule organizing center
0.33	GO:0005737	cytoplasm
0.30	GO:0031224	intrinsic component of membrane

sp|Q02846|GUC2D_HUMAN
Retinal guanylyl cyclase 1
Search

GUCY2D

0.57	Guanylate cyclase

0.82	GO:0006182	cGMP biosynthetic process
0.63	GO:0006468	protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.47	GO:0007601	visual perception
0.45	GO:0050962	detection of light stimulus involved in sensory perception
0.44	GO:0035845	photoreceptor cell outer segment organization
0.43	GO:0009584	detection of visible light

0.82	GO:0004383	guanylate cyclase activity
0.63	GO:0004672	protein kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0004016	adenylate cyclase activity

0.50	GO:0008074	guanylate cyclase complex, soluble
0.39	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.82

EC:4.6.1.2

GO:0004383

sp|Q02878|RL6_HUMAN
60S ribosomal protein L6
Search

RPL6

0.71	LOW QUALITY PROTEIN: 60S ribosomal protein L6

0.59	GO:0043043	peptide biosynthetic process
0.55	GO:0044267	cellular protein metabolic process
0.53	GO:0010467	gene expression
0.52	GO:0009059	macromolecule biosynthetic process
0.45	GO:0000027	ribosomal large subunit assembly
0.36	GO:0031016	pancreas development
0.35	GO:0043009	chordate embryonic development
0.35	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription

0.63	GO:0003735	structural constituent of ribosome
0.44	GO:0045296	cadherin binding
0.40	GO:0003723	RNA binding
0.34	GO:0005247	voltage-gated chloride channel activity
0.33	GO:0003677	DNA binding
0.33	GO:0016874	ligase activity

0.61	GO:0005840	ribosome
0.47	GO:0044445	cytosolic part
0.46	GO:0005844	polysome
0.44	GO:0036464	cytoplasmic ribonucleoprotein granule
0.41	GO:0044446	intracellular organelle part
0.39	GO:0005634	nucleus
0.36	GO:0005925	focal adhesion
0.35	GO:0031672	A band
0.35	GO:0005791	rough endoplasmic reticulum
0.34	GO:0098562	cytoplasmic side of membrane

0.33

GO:0016874

sp|Q02880|TOP2B_HUMAN
DNA topoisomerase 2-beta
Search

TOP2B

0.64	DNA topoisomerase 2-beta

0.72	GO:0006265	DNA topological change
0.55	GO:0007409	axonogenesis
0.55	GO:0001764	neuron migration
0.53	GO:0030900	forebrain development
0.49	GO:0000712	resolution of meiotic recombination intermediates
0.48	GO:0044774	mitotic DNA integrity checkpoint
0.46	GO:0000819	sister chromatid segregation
0.42	GO:0010842	retina layer formation
0.41	GO:0097485	neuron projection guidance
0.39	GO:0030263	apoptotic chromosome condensation

0.74	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity
0.57	GO:0005080	protein kinase C binding
0.56	GO:0042826	histone deacetylase binding
0.55	GO:0008022	protein C-terminus binding
0.55	GO:0030554	adenyl nucleotide binding
0.55	GO:0003677	DNA binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.52	GO:0003682	chromatin binding

0.54	GO:0000792	heterochromatin
0.49	GO:0005654	nucleoplasm
0.47	GO:0005829	cytosol
0.39	GO:0005730	nucleolus
0.38	GO:0009330	DNA topoisomerase complex (ATP-hydrolyzing)
0.37	GO:0030529	intracellular ribonucleoprotein complex
0.37	GO:0000793	condensed chromosome
0.36	GO:0005814	centriole
0.35	GO:0000228	nuclear chromosome
0.35	GO:0019035	viral integration complex

0.74

EC:5.99.1.3

GO:0003918

sp|Q02928|CP4AB_HUMAN
Cytochrome P450 4A11
Search

0.97	Fatty acid omega-hydroxylase

0.53	GO:0055114	oxidation-reduction process
0.45	GO:0006690	icosanoid metabolic process
0.44	GO:0033559	unsaturated fatty acid metabolic process
0.43	GO:0001676	long-chain fatty acid metabolic process
0.41	GO:1901569	fatty acid derivative catabolic process
0.40	GO:0009062	fatty acid catabolic process
0.40	GO:1901616	organic hydroxy compound catabolic process
0.39	GO:0048252	lauric acid metabolic process
0.39	GO:0003095	pressure natriuresis
0.38	GO:0032305	positive regulation of icosanoid secretion

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.64	GO:0004497	monooxygenase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding
0.44	GO:0103002	16-hydroxypalmitate dehydrogenase activity
0.35	GO:0019825	oxygen binding
0.35	GO:0050544	arachidonic acid binding

0.43	GO:0005789	endoplasmic reticulum membrane
0.41	GO:0016324	apical plasma membrane
0.40	GO:0005615	extracellular space
0.39	GO:0031090	organelle membrane
0.35	GO:1903561	extracellular vesicle
0.30	GO:0031224	intrinsic component of membrane

0.68

GO:0016705

sp|Q02930|CREB5_HUMAN
Cyclic AMP-responsive element-binding protein 5
Search

CREB5

0.97	Cyclic AMP-responsive element-binding protein 5

0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.50	GO:0051254	positive regulation of RNA metabolic process
0.49	GO:0010557	positive regulation of macromolecule biosynthetic process
0.49	GO:0031328	positive regulation of cellular biosynthetic process
0.38	GO:0060612	adipose tissue development
0.38	GO:0045444	fat cell differentiation
0.38	GO:0006366	transcription by RNA polymerase II

0.60	GO:0003700	DNA binding transcription factor activity
0.47	GO:0003676	nucleic acid binding
0.33	GO:0005515	protein binding
0.33	GO:0046872	metal ion binding

0.38	GO:0070062	extracellular exosome
0.36	GO:0005634	nucleus

sp|Q02952|AKA12_HUMAN
A-kinase anchor protein 12
Search

AKAP12

0.96	A-kinase anchoring protein 12

0.86	GO:0010739	positive regulation of protein kinase A signaling
0.86	GO:0090036	regulation of protein kinase C signaling
0.70	GO:0006605	protein targeting
0.60	GO:0007165	signal transduction
0.49	GO:0016310	phosphorylation
0.36	GO:0030819	positive regulation of cAMP biosynthetic process
0.36	GO:1904969	slow muscle cell migration
0.35	GO:0032060	bleb assembly
0.35	GO:0060028	convergent extension involved in axis elongation
0.35	GO:0035024	negative regulation of Rho protein signal transduction

0.84	GO:0051018	protein kinase A binding
0.62	GO:0008179	adenylate cyclase binding
0.50	GO:0016301	kinase activity
0.36	GO:0030159	receptor signaling complex scaffold activity

0.50	GO:0005829	cytosol
0.44	GO:0005886	plasma membrane
0.39	GO:0005925	focal adhesion
0.38	GO:0005856	cytoskeleton
0.37	GO:0005938	cell cortex
0.34	GO:0048471	perinuclear region of cytoplasm

sp|Q02962|PAX2_HUMAN
Paired box protein Pax-2
Search

PAX2

0.93	Paired box protein Pax-2

0.69	GO:0007275	multicellular organism development
0.61	GO:0045918	negative regulation of cytolysis
0.58	GO:2000378	negative regulation of reactive oxygen species metabolic process
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0061138	morphogenesis of a branching epithelium
0.56	GO:0050679	positive regulation of epithelial cell proliferation

0.54	GO:0003677	DNA binding
0.52	GO:0001067	regulatory region nucleic acid binding
0.51	GO:0008134	transcription factor binding
0.42	GO:0016175	superoxide-generating NADPH oxidase activity
0.40	GO:0070742	C2H2 zinc finger domain binding
0.38	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.58	GO:0034451	centriolar satellite
0.50	GO:0005794	Golgi apparatus
0.48	GO:0070013	intracellular organelle lumen
0.39	GO:0032993	protein-DNA complex
0.39	GO:0005764	lysosome
0.36	GO:0043234	protein complex

0.42

EC:1.6.3

GO:0016175

sp|Q02978|M2OM_HUMAN
Mitochondrial 2-oxoglutarate/malate carrier protein
Search

SLC25A11

0.59	RAN guanine nucleotide release factor

0.57	GO:0006839	mitochondrial transport
0.50	GO:0015742	alpha-ketoglutarate transport
0.37	GO:0030488	tRNA methylation
0.34	GO:0019319	hexose biosynthetic process
0.34	GO:0006006	glucose metabolic process
0.33	GO:0055085	transmembrane transport

0.51	GO:0015367	oxoglutarate:malate antiporter activity
0.38	GO:0016429	tRNA (adenine-N1-)-methyltransferase activity
0.34	GO:0003723	RNA binding
0.34	GO:0003779	actin binding

0.51	GO:0031966	mitochondrial membrane
0.45	GO:0019866	organelle inner membrane
0.38	GO:0031515	tRNA (m1A) methyltransferase complex
0.34	GO:0005634	nucleus
0.33	GO:0005887	integral component of plasma membrane
0.33	GO:0019013	viral nucleocapsid
0.33	GO:0030529	intracellular ribonucleoprotein complex

0.38

GO:0016429

sp|Q02985|FHR3_HUMAN
Complement factor H-related protein 3
Search

0.77	Complement factor H

0.65	GO:0006956	complement activation
0.55	GO:0045919	positive regulation of cytolysis
0.54	GO:0030449	regulation of complement activation
0.49	GO:0045087	innate immune response
0.46	GO:0032091	negative regulation of protein binding
0.42	GO:0070301	cellular response to hydrogen peroxide
0.41	GO:0071222	cellular response to lipopolysaccharide
0.40	GO:0071345	cellular response to cytokine stimulus
0.38	GO:0016032	viral process

0.67	GO:0043395	heparan sulfate proteoglycan binding
0.64	GO:0008201	heparin binding
0.49	GO:0001851	complement component C3b binding
0.43	GO:0042803	protein homodimerization activity
0.43	GO:0046982	protein heterodimerization activity

0.62	GO:0072562	blood microparticle
0.59	GO:0070062	extracellular exosome
0.39	GO:0043234	protein complex
0.37	GO:0005634	nucleus
0.36	GO:0005886	plasma membrane
0.34	GO:0005737	cytoplasm

sp|Q03001|DYST_HUMAN
Dystonin
Search

DST

0.77

Dystonin

0.39	GO:0008090	retrograde axonal transport
0.38	GO:0045104	intermediate filament cytoskeleton organization
0.37	GO:0007409	axonogenesis
0.37	GO:0031581	hemidesmosome assembly
0.37	GO:0030011	maintenance of cell polarity
0.36	GO:0031122	cytoplasmic microtubule organization
0.36	GO:0031110	regulation of microtubule polymerization or depolymerization
0.36	GO:0009611	response to wounding
0.35	GO:0048870	cell motility
0.34	GO:0007155	cell adhesion

0.72	GO:0008017	microtubule binding
0.68	GO:0005509	calcium ion binding
0.65	GO:0003779	actin binding
0.42	GO:0002162	dystroglycan binding
0.37	GO:0042803	protein homodimerization activity
0.36	GO:0005178	integrin binding
0.36	GO:0008022	protein C-terminus binding

0.62	GO:0005856	cytoskeleton
0.39	GO:0031673	H zone
0.39	GO:0030056	hemidesmosome
0.38	GO:0097038	perinuclear endoplasmic reticulum
0.38	GO:0014704	intercalated disc
0.38	GO:1904115	axon cytoplasm
0.38	GO:0042383	sarcolemma
0.38	GO:0030018	Z disc
0.38	GO:0014069	postsynaptic density
0.37	GO:0005925	focal adhesion

sp|Q03013|GSTM4_HUMAN
Glutathione S-transferase Mu 4
Search

0.42	Glutathione S-transferase

0.54	GO:0018916	nitrobenzene metabolic process
0.50	GO:0006749	glutathione metabolic process
0.48	GO:0042178	xenobiotic catabolic process
0.47	GO:0070458	cellular detoxification of nitrogen compound
0.42	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity
0.41	GO:0071313	cellular response to caffeine
0.41	GO:0043651	linoleic acid metabolic process
0.41	GO:1901685	glutathione derivative metabolic process
0.41	GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity
0.41	GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum

0.78	GO:0004364	glutathione transferase activity
0.51	GO:0043295	glutathione binding
0.48	GO:0042802	identical protein binding
0.45	GO:0019899	enzyme binding
0.44	GO:0046983	protein dimerization activity
0.39	GO:0004602	glutathione peroxidase activity
0.38	GO:0005102	receptor binding

0.56	GO:0045171	intercellular bridge
0.48	GO:0005829	cytosol
0.40	GO:0016529	sarcoplasmic reticulum
0.34	GO:0070062	extracellular exosome

0.78

EC:2.5.1.18

GO:0004364

sp|Q03014|HHEX_HUMAN
Hematopoietically-expressed homeobox protein HHEX
Search

HHEX

0.97	Hematopoietically-expressed homeobox protein HHEX

0.62	GO:0061011	hepatic duct development
0.62	GO:0060431	primary lung bud formation
0.62	GO:0061017	hepatoblast differentiation
0.62	GO:0061010	gall bladder development
0.61	GO:0022027	interkinetic nuclear migration
0.61	GO:0070365	hepatocyte differentiation
0.60	GO:0090009	primitive streak formation
0.60	GO:0048853	forebrain morphogenesis
0.59	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway
0.59	GO:0030878	thyroid gland development

0.63	GO:0043565	sequence-specific DNA binding
0.60	GO:0071837	HMG box domain binding
0.59	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.59	GO:0008190	eukaryotic initiation factor 4E binding
0.58	GO:0008301	DNA binding, bending
0.58	GO:0070491	repressing transcription factor binding
0.56	GO:0001012	RNA polymerase II regulatory region DNA binding
0.55	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.53	GO:0003682	chromatin binding
0.53	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.51	GO:0032993	protein-DNA complex
0.40	GO:0005737	cytoplasm
0.33	GO:0030529	intracellular ribonucleoprotein complex
0.33	GO:0043232	intracellular non-membrane-bounded organelle

sp|Q03052|PO3F1_HUMAN
POU domain, class 3, transcription factor 1
Search

POU3F1

0.95	POU domain, class 3, transcription factor 1

0.76	GO:0007420	brain development
0.68	GO:0006357	regulation of transcription by RNA polymerase II
0.58	GO:0006351	transcription, DNA-templated
0.53	GO:0022008	neurogenesis
0.52	GO:0032292	peripheral nervous system axon ensheathment
0.51	GO:0030216	keratinocyte differentiation
0.51	GO:0007422	peripheral nervous system development
0.51	GO:0042552	myelination
0.50	GO:2001054	negative regulation of mesenchymal cell apoptotic process
0.49	GO:0090103	cochlea morphogenesis

0.65	GO:0043565	sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.52	GO:0001105	RNA polymerase II transcription coactivator activity
0.46	GO:0001012	RNA polymerase II regulatory region DNA binding
0.44	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.47	GO:0005667	transcription factor complex
0.44	GO:0031974	membrane-enclosed lumen
0.40	GO:0044446	intracellular organelle part

sp|Q03060|CREM_HUMAN
cAMP-responsive element modulator
Search

CREM

0.92	cAMP-responsive element modulator

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.48	GO:1902679	negative regulation of RNA biosynthetic process
0.45	GO:0006687	glycosphingolipid metabolic process
0.44	GO:0007283	spermatogenesis
0.42	GO:1902680	positive regulation of RNA biosynthetic process
0.40	GO:0048384	retinoic acid receptor signaling pathway
0.39	GO:0042752	regulation of circadian rhythm
0.39	GO:0048511	rhythmic process

0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0003677	DNA binding
0.50	GO:0001067	regulatory region nucleic acid binding
0.36	GO:0008140	cAMP response element binding protein binding

0.61	GO:0005634	nucleus
0.43	GO:0005667	transcription factor complex
0.33	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q03111|ENL_HUMAN
Protein ENL
Search

MLLT1

0.95	Myeloid/lymphoid or mixed-lineage leukemia translocated to, 1

0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.55	GO:0006469	negative regulation of protein kinase activity
0.45	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway
0.45	GO:0007379	segment specification
0.43	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.43	GO:0009952	anterior/posterior pattern specification
0.41	GO:0051254	positive regulation of RNA metabolic process
0.40	GO:0010557	positive regulation of macromolecule biosynthetic process

0.44	GO:0070577	lysine-acetylated histone binding
0.42	GO:0003682	chromatin binding
0.35	GO:0003743	translation initiation factor activity
0.34	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
0.33	GO:0003677	DNA binding

0.60	GO:0005634	nucleus
0.51	GO:0031974	membrane-enclosed lumen
0.49	GO:0005829	cytosol
0.46	GO:0043234	protein complex
0.45	GO:0044446	intracellular organelle part
0.45	GO:0043232	intracellular non-membrane-bounded organelle
0.34	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

0.34

EC:3.5.1

GO:0016811

sp|Q03112|EVI1_HUMAN
MDS1 and EVI1 complex locus protein EVI1
Search

0.90	Ecotropic virus integration site 1 protein like protein

0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:0010468	regulation of gene expression

0.51

GO:0003676

nucleic acid binding

sp|Q03113|GNA12_HUMAN
Guanine nucleotide-binding protein subunit alpha-12
Search

GNA12

0.95	Guanine nucleotide-binding protein subunit alpha-12

0.72	GO:0007264	small GTPase mediated signal transduction
0.68	GO:0007186	G-protein coupled receptor signaling pathway
0.48	GO:0048598	embryonic morphogenesis
0.48	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin
0.47	GO:0043149	stress fiber assembly
0.47	GO:0060973	cell migration involved in heart development
0.46	GO:0014003	oligodendrocyte development
0.46	GO:0090504	epiboly
0.45	GO:0009826	unidimensional cell growth
0.45	GO:0010762	regulation of fibroblast migration

0.78	GO:0031683	G-protein beta/gamma-subunit complex binding
0.76	GO:0001664	G-protein coupled receptor binding
0.65	GO:0003924	GTPase activity
0.63	GO:0019001	guanyl nucleotide binding
0.63	GO:0032550	purine ribonucleoside binding
0.62	GO:0004871	signal transducer activity
0.52	GO:0032555	purine ribonucleotide binding
0.52	GO:0035639	purine ribonucleoside triphosphate binding
0.36	GO:0045296	cadherin binding
0.35	GO:0046872	metal ion binding

0.44	GO:0031526	brush border membrane
0.44	GO:0005622	intracellular
0.43	GO:1905360	GTPase complex
0.42	GO:0019897	extrinsic component of plasma membrane
0.41	GO:0009898	cytoplasmic side of plasma membrane
0.40	GO:0016328	lateral plasma membrane
0.39	GO:0098797	plasma membrane protein complex
0.38	GO:0005925	focal adhesion

sp|Q03135|CAV1_HUMAN
Caveolin-1
Search

CAV1

0.82

Caveolin

0.85	GO:0070836	caveola assembly
0.66	GO:0031295	T cell costimulation
0.64	GO:0031623	receptor internalization
0.63	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
0.62	GO:1900085	negative regulation of peptidyl-tyrosine autophosphorylation
0.62	GO:1903609	negative regulation of inward rectifier potassium channel activity
0.61	GO:0033484	nitric oxide homeostasis
0.61	GO:0086098	angiotensin-activated signaling pathway involved in heart process
0.61	GO:0060355	positive regulation of cell adhesion molecule production
0.61	GO:0048550	negative regulation of pinocytosis

0.62	GO:0070320	inward rectifier potassium channel inhibitor activity
0.60	GO:0050998	nitric-oxide synthase binding
0.57	GO:0044325	ion channel binding
0.57	GO:0048365	Rac GTPase binding
0.57	GO:0051117	ATPase binding
0.56	GO:0016504	peptidase activator activity
0.55	GO:0032947	protein complex scaffold activity
0.54	GO:0030674	protein binding, bridging
0.54	GO:0019901	protein kinase binding
0.51	GO:0042802	identical protein binding

0.84	GO:0005901	caveola
0.74	GO:0000139	Golgi membrane
0.58	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex
0.58	GO:0002080	acrosomal membrane
0.58	GO:0005768	endosome
0.55	GO:0005925	focal adhesion
0.54	GO:0048471	perinuclear region of cytoplasm
0.52	GO:0005929	cilium
0.52	GO:0005938	cell cortex
0.48	GO:0005887	integral component of plasma membrane

sp|Q03154|ACY1_HUMAN
Aminoacylase-1
Search

ACY1

0.78	Aminoacylase 1

0.60	GO:0006508	proteolysis
0.60	GO:0006520	cellular amino acid metabolic process
0.35	GO:0030163	protein catabolic process
0.35	GO:0006805	xenobiotic metabolic process
0.33	GO:0006886	intracellular protein transport

0.85	GO:0004046	aminoacylase activity
0.67	GO:0008237	metallopeptidase activity
0.36	GO:0005515	protein binding
0.35	GO:0046872	metal ion binding

0.49	GO:0005737	cytoplasm
0.37	GO:0070062	extracellular exosome
0.32	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.85

EC:3.5.1.14

GO:0004046

sp|Q03164|KMT2A_HUMAN
Histone-lysine N-methyltransferase 2A
Search

KMT2A

0.51	Histone-lysine N-methyltransferase

0.82	GO:0051568	histone H3-K4 methylation
0.66	GO:1901674	regulation of histone H3-K27 acetylation
0.65	GO:2001040	positive regulation of cellular response to drug
0.64	GO:0048172	regulation of short-term neuronal synaptic plasticity
0.63	GO:0071440	regulation of histone H3-K14 acetylation
0.63	GO:0043984	histone H4-K16 acetylation
0.63	GO:0051571	positive regulation of histone H3-K4 methylation
0.63	GO:0035640	exploration behavior
0.63	GO:0060216	definitive hemopoiesis
0.63	GO:2000615	regulation of histone H3-K9 acetylation

0.84	GO:0042800	histone methyltransferase activity (H3-K4 specific)
0.63	GO:0045322	unmethylated CpG binding
0.62	GO:0070577	lysine-acetylated histone binding
0.61	GO:0008270	zinc ion binding
0.60	GO:0001046	core promoter sequence-specific DNA binding
0.56	GO:0003682	chromatin binding
0.56	GO:0042803	protein homodimerization activity
0.37	GO:0003680	AT DNA binding
0.35	GO:0034450	ubiquitin-ubiquitin ligase activity
0.34	GO:0003700	DNA binding transcription factor activity

0.82	GO:0071339	MLL1 complex
0.52	GO:0005829	cytosol
0.36	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
0.34	GO:0000151	ubiquitin ligase complex
0.32	GO:0030136	clathrin-coated vesicle

sp|Q03167|TGBR3_HUMAN
Transforming growth factor beta receptor type 3
Search

TGFBR3

0.96	Transforming growth factor beta receptor type 3

0.64	GO:0034699	response to luteinizing hormone
0.63	GO:0032354	response to follicle-stimulating hormone
0.62	GO:0060317	cardiac epithelial to mesenchymal transition
0.62	GO:0060389	pathway-restricted SMAD protein phosphorylation
0.62	GO:0034695	response to prostaglandin E
0.59	GO:0030509	BMP signaling pathway
0.59	GO:0007179	transforming growth factor beta receptor signaling pathway
0.58	GO:0051271	negative regulation of cellular component movement
0.54	GO:0006955	immune response
0.48	GO:0035556	intracellular signal transduction

0.67	GO:0070123	transforming growth factor beta receptor activity, type III
0.63	GO:0050431	transforming growth factor beta binding
0.62	GO:0005114	type II transforming growth factor beta receptor binding
0.60	GO:0015026	coreceptor activity
0.59	GO:0046332	SMAD binding
0.44	GO:0005539	glycosaminoglycan binding
0.42	GO:0048185	activin binding
0.41	GO:0017134	fibroblast growth factor binding
0.40	GO:0030165	PDZ domain binding
0.39	GO:1901681	sulfur compound binding

0.63	GO:0005576	extracellular region
0.63	GO:0034673	inhibin-betaglycan-ActRII complex
0.58	GO:0009897	external side of plasma membrane
0.56	GO:0043235	receptor complex
0.41	GO:0005887	integral component of plasma membrane
0.38	GO:0005622	intracellular
0.36	GO:0031982	vesicle
0.35	GO:0012505	endomembrane system

sp|Q03169|TNAP2_HUMAN
Tumor necrosis factor alpha-induced protein 2
Search

TNFAIP2

0.92	TNF alpha induced protein 2

0.77	GO:0006887	exocytosis
0.58	GO:0051601	exocyst localization

0.54

GO:0000149

SNARE binding

0.79

GO:0000145

exocyst

sp|Q03181|PPARD_HUMAN
Peroxisome proliferator-activated receptor delta
Search

PPARD

0.96	Peroxisome proliferator-activated receptor delta b

0.78	GO:0030522	intracellular receptor signaling pathway
0.77	GO:0043401	steroid hormone mediated signaling pathway
0.60	GO:0051546	keratinocyte migration
0.59	GO:0043415	positive regulation of skeletal muscle tissue regeneration
0.59	GO:2000288	positive regulation of myoblast proliferation
0.59	GO:1902894	negative regulation of pri-miRNA transcription by RNA polymerase II
0.58	GO:0043616	keratinocyte proliferation
0.58	GO:0014842	regulation of skeletal muscle satellite cell proliferation
0.58	GO:0045662	negative regulation of myoblast differentiation
0.57	GO:0060612	adipose tissue development

0.81	GO:0004879	nuclear receptor activity
0.78	GO:0003707	steroid hormone receptor activity
0.63	GO:0043565	sequence-specific DNA binding
0.62	GO:0070539	linoleic acid binding
0.62	GO:0008270	zinc ion binding
0.55	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.51	GO:0008134	transcription factor binding
0.51	GO:0046982	protein heterodimerization activity
0.42	GO:0008144	drug binding
0.41	GO:0003713	transcription coactivator activity

0.60	GO:0005634	nucleus
0.50	GO:0000785	chromatin
0.48	GO:0070013	intracellular organelle lumen

sp|Q03188|CENPC_HUMAN
Centromere protein C
Search

CENPC

0.95	Centromere protein C

0.84	GO:0051382	kinetochore assembly
0.60	GO:0000278	mitotic cell cycle
0.58	GO:0007059	chromosome segregation
0.54	GO:0051303	establishment of chromosome localization
0.52	GO:0007127	meiosis I
0.40	GO:0034080	CENP-A containing nucleosome assembly
0.38	GO:0051301	cell division

0.85	GO:0019237	centromeric DNA binding
0.34	GO:0005515	protein binding

0.78	GO:0000776	kinetochore
0.68	GO:0090543	Flemming body
0.66	GO:0005721	pericentric heterochromatin
0.65	GO:0032154	cleavage furrow
0.65	GO:0045171	intercellular bridge
0.64	GO:0000780	condensed nuclear chromosome, centromeric region
0.61	GO:0016604	nuclear body
0.55	GO:0005829	cytosol
0.50	GO:0005720	nuclear heterochromatin
0.30	GO:0031224	intrinsic component of membrane

sp|Q03252|LMNB2_HUMAN
Lamin-B2
Search

0.10	Lamin-L(II)

0.35	GO:1904609	cellular response to monosodium L-glutamate
0.34	GO:0071386	cellular response to corticosterone stimulus
0.34	GO:0031662	positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle
0.34	GO:0035722	interleukin-12-mediated signaling pathway
0.34	GO:0046330	positive regulation of JNK cascade
0.33	GO:0015031	protein transport
0.33	GO:0006915	apoptotic process
0.33	GO:0022008	neurogenesis
0.33	GO:0046677	response to antibiotic
0.33	GO:0042493	response to drug

0.62	GO:0005198	structural molecule activity
0.46	GO:0043274	phospholipase binding
0.34	GO:0008432	JUN kinase binding
0.32	GO:0046872	metal ion binding

0.79	GO:0005882	intermediate filament
0.61	GO:0005652	nuclear lamina
0.58	GO:0005635	nuclear envelope
0.47	GO:0031090	organelle membrane
0.44	GO:0016363	nuclear matrix
0.40	GO:0005654	nucleoplasm
0.33	GO:0005739	mitochondrion

sp|Q03393|PTPS_HUMAN
6-pyruvoyl tetrahydrobiopterin synthase
Search

PTS

0.71	6-pyruvoyl tetrahydrobiopterin synthase

0.80	GO:0046146	tetrahydrobiopterin metabolic process
0.80	GO:0034312	diol biosynthetic process
0.72	GO:0042559	pteridine-containing compound biosynthetic process
0.65	GO:0009108	coenzyme biosynthetic process
0.34	GO:0007417	central nervous system development
0.34	GO:0008616	queuosine biosynthetic process
0.33	GO:0046655	folic acid metabolic process
0.33	GO:0006979	response to oxidative stress
0.33	GO:0042398	cellular modified amino acid biosynthetic process
0.33	GO:0043650	dicarboxylic acid biosynthetic process

0.85	GO:0003874	6-pyruvoyltetrahydropterin synthase activity
0.48	GO:0042802	identical protein binding
0.45	GO:0046983	protein dimerization activity
0.44	GO:0046872	metal ion binding
0.34	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
0.32	GO:0003677	DNA binding

0.42	GO:0005739	mitochondrion
0.34	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.85	EC:4.2.3.12	GO:0003874
0.85	KEGG:R04286	GO:0003874

sp|Q03395|ROM1_HUMAN
Rod outer segment membrane protein 1
Search

ROM1

0.92	Retinal outer segment membrane protein 1

0.78	GO:0007601	visual perception
0.62	GO:0060041	retina development in camera-type eye
0.58	GO:0001754	eye photoreceptor cell differentiation
0.57	GO:0048593	camera-type eye morphogenesis
0.55	GO:0001944	vasculature development
0.47	GO:0007166	cell surface receptor signaling pathway
0.43	GO:0060255	regulation of macromolecule metabolic process
0.41	GO:0007155	cell adhesion
0.34	GO:1903525	regulation of membrane tubulation
0.34	GO:0009645	response to low light intensity stimulus

0.34

GO:0005515

protein binding

0.63	GO:0001750	photoreceptor outer segment
0.58	GO:0060170	ciliary membrane
0.45	GO:0005887	integral component of plasma membrane
0.34	GO:0055037	recycling endosome
0.33	GO:0005795	Golgi stack
0.33	GO:0005783	endoplasmic reticulum
0.32	GO:0043234	protein complex

sp|Q03403|TFF2_HUMAN
Trefoil factor 2
Search

TFF2

0.95	trefoil factor 2

0.76	GO:0007586	digestion
0.65	GO:0042060	wound healing
0.59	GO:0010669	epithelial structure maintenance
0.59	GO:0010906	regulation of glucose metabolic process
0.52	GO:0003008	system process
0.46	GO:0008285	negative regulation of cell proliferation
0.45	GO:0010469	regulation of receptor activity
0.44	GO:0030154	cell differentiation
0.37	GO:0043434	response to peptide hormone
0.36	GO:0006952	defense response

0.46	GO:0008083	growth factor activity
0.38	GO:0030246	carbohydrate binding
0.36	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds

0.60	GO:0005615	extracellular space
0.58	GO:0030141	secretory granule
0.44	GO:0005578	proteinaceous extracellular matrix
0.40	GO:1903561	extracellular vesicle
0.30	GO:0016020	membrane

0.36

GO:0004553

sp|Q03405|UPAR_HUMAN
Urokinase plasminogen activator surface receptor
Search

PLAUR

0.97	Urokinase plasminogen activator surface receptor

0.87	GO:0038195	urokinase plasminogen activator signaling pathway
0.74	GO:0030162	regulation of proteolysis
0.70	GO:0090200	positive regulation of release of cytochrome c from mitochondria
0.69	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway
0.68	GO:0043388	positive regulation of DNA binding
0.67	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway
0.62	GO:0001934	positive regulation of protein phosphorylation
0.60	GO:0051346	negative regulation of hydrolase activity
0.58	GO:0032269	negative regulation of cellular protein metabolic process
0.47	GO:0016310	phosphorylation

0.87	GO:0030377	urokinase plasminogen activator receptor activity
0.61	GO:0019904	protein domain specific binding
0.59	GO:0005102	receptor binding
0.58	GO:0019899	enzyme binding
0.48	GO:0016301	kinase activity

0.61	GO:0009986	cell surface
0.55	GO:0005887	integral component of plasma membrane
0.52	GO:0071438	invadopodium membrane
0.51	GO:0031225	anchored component of membrane
0.47	GO:0030054	cell junction
0.41	GO:0070062	extracellular exosome
0.40	GO:0035579	specific granule membrane
0.39	GO:0005788	endoplasmic reticulum lumen
0.39	GO:0045177	apical part of cell
0.38	GO:0019898	extrinsic component of membrane

sp|Q03426|KIME_HUMAN
Mevalonate kinase
Search

MVK

0.59	Mevalonate kinase

0.82	GO:0006695	cholesterol biosynthetic process
0.80	GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway
0.57	GO:0050728	negative regulation of inflammatory response
0.57	GO:0016310	phosphorylation
0.38	GO:0045540	regulation of cholesterol biosynthetic process
0.36	GO:0010142	farnesyl diphosphate biosynthetic process, mevalonate pathway
0.35	GO:0006696	ergosterol biosynthetic process
0.34	GO:0017148	negative regulation of translation

0.81	GO:0004496	mevalonate kinase activity
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0042802	identical protein binding
0.36	GO:1990825	sequence-specific mRNA binding
0.35	GO:0005534	galactose binding

0.50	GO:0005829	cytosol
0.37	GO:0005777	peroxisome
0.37	GO:0070062	extracellular exosome
0.30	GO:0016020	membrane

0.81	EC:2.7.1.36	GO:0004496
0.81	KEGG:R02245	GO:0004496

sp|Q03431|PTH1R_HUMAN
Parathyroid hormone/parathyroid hormone-related peptide receptor
Search

PTH1R

0.92	Parathyroid hormone 1 receptor a

0.70	GO:0007166	cell surface receptor signaling pathway
0.70	GO:0007186	G-protein coupled receptor signaling pathway
0.60	GO:0002076	osteoblast development
0.59	GO:0045453	bone resorption
0.58	GO:0030282	bone mineralization
0.58	GO:0019933	cAMP-mediated signaling
0.58	GO:0002062	chondrocyte differentiation
0.56	GO:0048469	cell maturation
0.55	GO:0006874	cellular calcium ion homeostasis
0.54	GO:0008285	negative regulation of cell proliferation

0.86	GO:0004991	parathyroid hormone receptor activity
0.64	GO:0017046	peptide hormone binding
0.59	GO:0043621	protein self-association
0.53	GO:0042803	protein homodimerization activity

0.51	GO:0005886	plasma membrane
0.40	GO:0005903	brush border
0.40	GO:0045177	apical part of cell
0.39	GO:0043235	receptor complex
0.39	GO:0120038	plasma membrane bounded cell projection part
0.38	GO:0005622	intracellular
0.37	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

sp|Q03468|ERCC6_HUMAN
DNA excision repair protein ERCC-6
Search

ERCC6

0.89	Excision repair cross-complementing rodent repair deficiency, complementation group 6

0.66	GO:0006362	transcription elongation from RNA polymerase I promoter
0.65	GO:0007256	activation of JNKK activity
0.65	GO:0007257	activation of JUN kinase activity
0.64	GO:0010165	response to X-ray
0.64	GO:0006290	pyrimidine dimer repair
0.64	GO:0061098	positive regulation of protein tyrosine kinase activity
0.63	GO:0045494	photoreceptor cell maintenance
0.63	GO:0010224	response to UV-B
0.63	GO:0010332	response to gamma radiation
0.63	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage

0.65	GO:0030296	protein tyrosine kinase activator activity
0.64	GO:0047485	protein N-terminus binding
0.62	GO:0008022	protein C-terminus binding
0.59	GO:0003682	chromatin binding
0.57	GO:0032403	protein complex binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008094	DNA-dependent ATPase activity
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0003677	DNA binding

0.60	GO:0008023	transcription elongation factor complex
0.56	GO:0005730	nucleolus
0.30	GO:0016020	membrane

0.32

EC:2

GO:0016740

sp|Q03518|TAP1_HUMAN
Antigen peptide transporter 1
Search

TAP1

0.95	Transporter associated with antigen processing 1

0.85	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I
0.65	GO:0042886	amide transport
0.61	GO:0071702	organic substance transport
0.60	GO:0046967	cytosol to ER transport
0.55	GO:0055085	transmembrane transport
0.50	GO:0006952	defense response
0.43	GO:0002478	antigen processing and presentation of exogenous peptide antigen
0.43	GO:0002488	antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway
0.42	GO:0001910	regulation of leukocyte mediated cytotoxicity
0.41	GO:0002250	adaptive immune response

0.85	GO:0042287	MHC protein binding
0.85	GO:0015440	peptide-transporting ATPase activity
0.85	GO:0046977	TAP binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0046980	tapasin binding
0.39	GO:0042605	peptide antigen binding
0.37	GO:0042803	protein homodimerization activity
0.36	GO:0070003	threonine-type peptidase activity

0.86	GO:0042825	TAP complex
0.51	GO:0005815	microtubule organizing center
0.45	GO:0005739	mitochondrion
0.39	GO:0030670	phagocytic vesicle membrane
0.37	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane
0.37	GO:0016607	nuclear speck
0.36	GO:0042613	MHC class II protein complex
0.36	GO:0005839	proteasome core complex
0.32	GO:0005887	integral component of plasma membrane

0.85

EC:3.6.3.43

GO:0015440

sp|Q03519|TAP2_HUMAN
Antigen peptide transporter 2
Search

TAP2

0.31	Major histocompatibility complex class I

0.85	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I
0.64	GO:0042886	amide transport
0.60	GO:0071702	organic substance transport
0.55	GO:0055085	transmembrane transport
0.51	GO:0002489	antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent
0.50	GO:0002481	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
0.49	GO:0001916	positive regulation of T cell mediated cytotoxicity
0.47	GO:0046967	cytosol to ER transport
0.46	GO:0002237	response to molecule of bacterial origin
0.43	GO:0006955	immune response

0.85	GO:0042287	MHC protein binding
0.85	GO:0015440	peptide-transporting ATPase activity
0.62	GO:0046977	TAP binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0046980	tapasin binding
0.37	GO:0042605	peptide antigen binding
0.35	GO:0042803	protein homodimerization activity
0.35	GO:0046982	protein heterodimerization activity

0.86	GO:0042825	TAP complex
0.41	GO:0016607	nuclear speck
0.41	GO:0042613	MHC class II protein complex
0.41	GO:0005815	microtubule organizing center
0.37	GO:0005739	mitochondrion
0.37	GO:0030670	phagocytic vesicle membrane
0.36	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane
0.34	GO:0005839	proteasome core complex
0.33	GO:0005887	integral component of plasma membrane

0.85

EC:3.6.3.43

GO:0015440

sp|Q03591|FHR1_HUMAN
Complement factor H-related protein 1
Search

0.89	Complement factor H-related protein B

0.72	GO:0045919	positive regulation of cytolysis
0.66	GO:0032091	negative regulation of protein binding
0.58	GO:0006956	complement activation
0.54	GO:0030449	regulation of complement activation
0.47	GO:0045087	innate immune response

0.60	GO:0042803	protein homodimerization activity
0.59	GO:0046982	protein heterodimerization activity
0.48	GO:0043395	heparan sulfate proteoglycan binding
0.46	GO:0008201	heparin binding
0.43	GO:0001851	complement component C3b binding

0.56	GO:0072562	blood microparticle
0.54	GO:0070062	extracellular exosome
0.49	GO:0043234	protein complex
0.30	GO:0016020	membrane

sp|Q03692|COAA1_HUMAN
Collagen alpha-1(X) chain
Search

COL10A1

0.93	Collagen type VIII alpha 2 chain

0.44	GO:0009887	animal organ morphogenesis
0.44	GO:0050673	epithelial cell proliferation
0.43	GO:0043010	camera-type eye development
0.39	GO:0036075	replacement ossification
0.39	GO:0001501	skeletal system development
0.38	GO:0061448	connective tissue development
0.34	GO:0030574	collagen catabolic process
0.34	GO:0030198	extracellular matrix organization

0.37	GO:0005201	extracellular matrix structural constituent
0.33	GO:0005515	protein binding
0.32	GO:0046872	metal ion binding

0.79	GO:0005581	collagen trimer
0.61	GO:0005576	extracellular region
0.51	GO:0005938	cell cortex
0.36	GO:0043235	receptor complex
0.34	GO:0005788	endoplasmic reticulum lumen

sp|Q03701|CEBPZ_HUMAN
CCAAT/enhancer-binding protein zeta
Search

CEBPZ

0.94	CCAAT/enhancer-binding protein zeta

0.74	GO:0006366	transcription by RNA polymerase II
0.73	GO:0045944	positive regulation of transcription by RNA polymerase II

0.80	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.78	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.37	GO:0003723	RNA binding

0.50	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q03721|KCNC4_HUMAN
Potassium voltage-gated channel subfamily C member 4
Search

KCNC4

0.96	Potassium voltage-gated channel subfamily C member 4

0.75	GO:0051260	protein homooligomerization
0.75	GO:0034765	regulation of ion transmembrane transport
0.73	GO:0071805	potassium ion transmembrane transport
0.56	GO:0046928	regulation of neurotransmitter secretion
0.37	GO:0030900	forebrain development
0.37	GO:0038060	nitric oxide-cGMP-mediated signaling pathway
0.37	GO:0071732	cellular response to nitric oxide
0.37	GO:0032026	response to magnesium ion
0.37	GO:1904057	negative regulation of sensory perception of pain
0.36	GO:1990089	response to nerve growth factor

0.77	GO:0005249	voltage-gated potassium channel activity
0.36	GO:0044325	ion channel binding
0.33	GO:0003723	RNA binding

0.78	GO:0008076	voltage-gated potassium channel complex
0.56	GO:0043679	axon terminus
0.56	GO:0031594	neuromuscular junction
0.37	GO:0043025	neuronal cell body
0.37	GO:0030425	dendrite
0.37	GO:0030424	axon
0.37	GO:0044298	cell body membrane
0.36	GO:0098794	postsynapse
0.36	GO:0032589	neuron projection membrane
0.36	GO:0031982	vesicle

sp|Q03828|EVX2_HUMAN
Homeobox even-skipped homolog protein 2
Search

EVX1

0.96	Homeobox even-skipped like protein 1

0.58	GO:0035108	limb morphogenesis
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.53	GO:0021521	ventral spinal cord interneuron specification
0.49	GO:0009792	embryo development ending in birth or egg hatching
0.46	GO:1902680	positive regulation of RNA biosynthetic process
0.38	GO:0033334	fin morphogenesis
0.32	GO:0006351	transcription, DNA-templated

0.63	GO:0043565	sequence-specific DNA binding
0.33	GO:0003700	DNA binding transcription factor activity

0.61	GO:0005634	nucleus
0.44	GO:0031974	membrane-enclosed lumen
0.40	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

sp|Q03923|ZNF85_HUMAN
Zinc finger protein 85
Search

0.79	Zinc finger protein 680

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.43	GO:0097659	nucleic acid-templated transcription
0.41	GO:0010467	gene expression
0.40	GO:0034645	cellular macromolecule biosynthetic process

0.54	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding

0.45	GO:0005622	intracellular
0.42	GO:0043227	membrane-bounded organelle

sp|Q03924|ZN117_HUMAN
Zinc finger protein 117
Search

0.74	Zinc finger protein 117

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.54	GO:0010468	regulation of gene expression
0.38	GO:0030154	cell differentiation
0.38	GO:1902679	negative regulation of RNA biosynthetic process
0.38	GO:0044092	negative regulation of molecular function
0.37	GO:0006351	transcription, DNA-templated

0.52	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.39	GO:0003682	chromatin binding
0.36	GO:0003700	DNA binding transcription factor activity

0.44	GO:0005622	intracellular
0.36	GO:0043227	membrane-bounded organelle

sp|Q03933|HSF2_HUMAN
Heat shock factor protein 2
Search

HSF2

0.97	LOW QUALITY PROTEIN: heat shock factor protein 2

0.68	GO:0006357	regulation of transcription by RNA polymerase II
0.53	GO:0006366	transcription by RNA polymerase II
0.52	GO:0045893	positive regulation of transcription, DNA-templated
0.52	GO:0007283	spermatogenesis
0.39	GO:0070207	protein homotrimerization
0.39	GO:1903935	response to sodium arsenite
0.38	GO:0009628	response to abiotic stimulus
0.37	GO:0031397	negative regulation of protein ubiquitination
0.37	GO:1901698	response to nitrogen compound
0.36	GO:0050821	protein stabilization

0.64	GO:0043565	sequence-specific DNA binding
0.61	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding
0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0001012	RNA polymerase II regulatory region DNA binding
0.52	GO:0003690	double-stranded DNA binding
0.51	GO:0042803	protein homodimerization activity
0.37	GO:0001047	core promoter binding
0.35	GO:0003713	transcription coactivator activity
0.35	GO:1990841	promoter-specific chromatin binding
0.35	GO:0043621	protein self-association

0.61	GO:0005634	nucleus
0.50	GO:0070013	intracellular organelle lumen
0.45	GO:0044446	intracellular organelle part
0.39	GO:0005737	cytoplasm
0.36	GO:0005694	chromosome
0.34	GO:0035770	ribonucleoprotein granule
0.34	GO:0015630	microtubule cytoskeleton
0.33	GO:0043234	protein complex

sp|Q03936|ZNF92_HUMAN
Zinc finger protein 92
Search

0.69	Zinc finger protein 92

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.41	GO:1902679	negative regulation of RNA biosynthetic process
0.40	GO:0006351	transcription, DNA-templated

0.52	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.30	GO:0003700	DNA binding transcription factor activity

0.44	GO:0005622	intracellular
0.39	GO:0043227	membrane-bounded organelle

sp|Q03938|ZNF90_HUMAN
Zinc finger protein 90
Search

0.82	Zinc finger protein 85

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.40	GO:0006351	transcription, DNA-templated
0.38	GO:1902679	negative regulation of RNA biosynthetic process

0.51	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.43	GO:0003700	DNA binding transcription factor activity
0.40	GO:0003714	transcription corepressor activity
0.36	GO:0005515	protein binding

0.45	GO:0005634	nucleus
0.38	GO:0070062	extracellular exosome
0.37	GO:0031974	membrane-enclosed lumen
0.35	GO:0043232	intracellular non-membrane-bounded organelle
0.35	GO:0044446	intracellular organelle part

sp|Q03989|ARI5A_HUMAN
AT-rich interactive domain-containing protein 5A
Search

ARID5A

0.97	AT-rich interactive domain-containing protein 5A

0.61	GO:0071391	cellular response to estrogen stimulus
0.56	GO:0000122	negative regulation of transcription by RNA polymerase II
0.42	GO:1905078	positive regulation of interleukin-17 secretion
0.42	GO:2000556	positive regulation of T-helper 1 cell cytokine production
0.41	GO:0061448	connective tissue development
0.41	GO:2000318	positive regulation of T-helper 17 type immune response
0.41	GO:1902715	positive regulation of interferon-gamma secretion
0.41	GO:1904469	positive regulation of tumor necrosis factor secretion
0.40	GO:2000778	positive regulation of interleukin-6 secretion
0.40	GO:0001501	skeletal system development

0.63	GO:0046965	retinoid X receptor binding
0.62	GO:0046966	thyroid hormone receptor binding
0.62	GO:0050681	androgen receptor binding
0.61	GO:0030331	estrogen receptor binding
0.58	GO:0003714	transcription corepressor activity
0.55	GO:0003677	DNA binding
0.48	GO:0001067	regulatory region nucleic acid binding
0.41	GO:0035613	RNA stem-loop binding
0.39	GO:0003682	chromatin binding
0.38	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.50	GO:0070013	intracellular organelle lumen
0.46	GO:0043232	intracellular non-membrane-bounded organelle
0.45	GO:0044446	intracellular organelle part
0.38	GO:0005667	transcription factor complex
0.35	GO:0044815	DNA packaging complex
0.30	GO:0016020	membrane

sp|Q04118|PRB3_HUMAN
Basic salivary proline-rich protein 3
Search

0.88	Basic salivary proline-rich protein 3

0.47	GO:0050829	defense response to Gram-negative bacterium
0.38	GO:0010469	regulation of receptor activity
0.38	GO:0006471	protein ADP-ribosylation
0.36	GO:0006470	protein dephosphorylation
0.36	GO:0080040	positive regulation of cellular response to phosphate starvation
0.35	GO:0042766	nucleosome mobilization
0.35	GO:0016584	nucleosome positioning
0.35	GO:0000722	telomere maintenance via recombination
0.35	GO:0060303	regulation of nucleosome density
0.35	GO:0009405	pathogenesis

0.43	GO:0052861	glucan endo-1,3-beta-glucanase activity, C-3 substituted reducing group
0.40	GO:0005515	protein binding
0.38	GO:0030545	receptor regulator activity
0.38	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity
0.37	GO:0004722	protein serine/threonine phosphatase activity
0.36	GO:0003723	RNA binding
0.35	GO:0008144	drug binding
0.35	GO:0004222	metalloendopeptidase activity
0.35	GO:0008270	zinc ion binding
0.35	GO:0016887	ATPase activity

0.55	GO:0005576	extracellular region
0.35	GO:0031011	Ino80 complex
0.35	GO:0000781	chromosome, telomeric region
0.33	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.43

EC:3.2.1.6

GO:0052861

sp|Q04206|TF65_HUMAN
Transcription factor p65
Search

RELA

0.96	V-rel reticuloendotheliosis viral oncogene A

0.82	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.60	GO:0071224	cellular response to peptidoglycan
0.59	GO:0071316	cellular response to nicotine
0.59	GO:0045084	positive regulation of interleukin-12 biosynthetic process
0.59	GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway
0.59	GO:2000630	positive regulation of miRNA metabolic process
0.59	GO:0061614	pri-miRNA transcription by RNA polymerase II
0.59	GO:0071223	cellular response to lipoteichoic acid
0.59	GO:1901223	negative regulation of NIK/NF-kappaB signaling
0.59	GO:0035729	cellular response to hepatocyte growth factor stimulus

0.61	GO:0003700	DNA binding transcription factor activity
0.60	GO:0071532	ankyrin repeat binding
0.58	GO:0051059	NF-kappaB binding
0.57	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.56	GO:0070491	repressing transcription factor binding
0.56	GO:0047485	protein N-terminus binding
0.56	GO:0033613	activating transcription factor binding
0.56	GO:0042826	histone deacetylase binding
0.55	GO:0031490	chromatin DNA binding
0.55	GO:0042805	actinin binding

0.86	GO:0071159	NF-kappaB complex
0.61	GO:0005634	nucleus
0.51	GO:0005667	transcription factor complex
0.51	GO:0033256	I-kappaB/NF-kappaB complex
0.50	GO:0005829	cytosol
0.50	GO:0000785	chromatin
0.48	GO:0070013	intracellular organelle lumen

sp|Q04323|UBXN1_HUMAN
UBX domain-containing protein 1
Search

UBXN1

0.93	UBX domain-containing protein 1-B

0.81	GO:1903093	regulation of protein K48-linked deubiquitination
0.81	GO:2000157	negative regulation of ubiquitin-specific protease activity
0.80	GO:0090086	negative regulation of protein deubiquitination
0.77	GO:1904293	negative regulation of ERAD pathway
0.76	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process
0.74	GO:0031397	negative regulation of protein ubiquitination
0.38	GO:0019915	lipid storage
0.38	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
0.36	GO:0006457	protein folding

0.82	GO:0071796	K6-linked polyubiquitin modification-dependent protein binding
0.78	GO:0036435	K48-linked polyubiquitin modification-dependent protein binding
0.74	GO:0051117	ATPase binding
0.71	GO:0043130	ubiquitin binding
0.69	GO:0031625	ubiquitin protein ligase binding
0.41	GO:0003676	nucleic acid binding

0.76	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex
0.64	GO:1905369	endopeptidase complex
0.60	GO:0005829	cytosol
0.45	GO:0043025	neuronal cell body
0.45	GO:0030425	dendrite
0.40	GO:0005634	nucleus
0.30	GO:0016021	integral component of membrane

sp|Q04446|GLGB_HUMAN
1,4-alpha-glucan-branching enzyme
Search

GBE1

0.44	Glycogen branching enzyme

0.77

GO:0005978

glycogen biosynthetic process

0.80	GO:0003844	1,4-alpha-glucan branching enzyme activity
0.65	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds
0.52	GO:0043169	cation binding
0.40	GO:0102752	1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis)
0.37	GO:0030246	carbohydrate binding
0.33	GO:0005515	protein binding

0.38	GO:0070062	extracellular exosome
0.34	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.80

EC:2.4.1.18

GO:0003844

sp|Q04609|FOLH1_HUMAN
Glutamate carboxypeptidase 2
Search

FOLH1

0.83	Prostate specific membrane antigen variant F

0.55	GO:0035609	C-terminal protein deglutamylation
0.53	GO:0006508	proteolysis
0.46	GO:0006760	folic acid-containing compound metabolic process
0.45	GO:0042135	neurotransmitter catabolic process
0.35	GO:0008652	cellular amino acid biosynthetic process
0.35	GO:0043065	positive regulation of apoptotic process

0.61	GO:0004180	carboxypeptidase activity
0.56	GO:1904493	tetrahydrofolyl-poly(glutamate) polymer binding
0.56	GO:1904492	Ac-Asp-Glu binding
0.50	GO:0016805	dipeptidase activity
0.50	GO:0050129	N-formylglutamate deformylase activity
0.47	GO:0008235	metalloexopeptidase activity
0.35	GO:0046872	metal ion binding
0.34	GO:0008239	dipeptidyl-peptidase activity
0.33	GO:0017171	serine hydrolase activity

0.47	GO:0009986	cell surface
0.45	GO:0005887	integral component of plasma membrane
0.38	GO:0070062	extracellular exosome
0.33	GO:0005737	cytoplasm

0.50	EC:3.4.13	GO:0016805
0.50	KEGG:R00525	GO:0050129

sp|Q04637|IF4G1_HUMAN
Eukaryotic translation initiation factor 4 gamma 1
Search

EIF4G1

0.91	Eukaryotic translation initiation factor 4 gamma 1

0.72	GO:0006413	translational initiation
0.58	GO:1905610	regulation of mRNA cap binding
0.58	GO:1905537	positive regulation of eukaryotic translation initiation factor 4F complex assembly
0.57	GO:1905618	positive regulation of miRNA mediated inhibition of translation
0.57	GO:1905696	regulation of polysome binding
0.57	GO:1905606	regulation of presynapse assembly
0.56	GO:2000507	positive regulation of energy homeostasis
0.56	GO:1902416	positive regulation of mRNA binding
0.54	GO:0001662	behavioral fear response
0.54	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle

0.76	GO:0003729	mRNA binding
0.73	GO:0003743	translation initiation factor activity
0.66	GO:0008190	eukaryotic initiation factor 4E binding
0.52	GO:0045296	cadherin binding
0.48	GO:0042802	identical protein binding
0.41	GO:0032559	adenyl ribonucleotide binding
0.40	GO:0008144	drug binding
0.40	GO:0035639	purine ribonucleoside triphosphate binding
0.35	GO:0032947	protein complex scaffold activity

0.55	GO:0016281	eukaryotic translation initiation factor 4F complex
0.52	GO:0005844	polysome
0.47	GO:0005829	cytosol
0.43	GO:0005634	nucleus
0.34	GO:0015935	small ribosomal subunit
0.30	GO:0016020	membrane

sp|Q04656|ATP7A_HUMAN
Copper-transporting ATPase 1
Search

ATP7A

0.75	ATPase copper transporting alpha

0.68	GO:0051353	positive regulation of oxidoreductase activity
0.68	GO:0099132	ATP hydrolysis coupled cation transmembrane transport
0.66	GO:0006878	cellular copper ion homeostasis
0.66	GO:0030001	metal ion transport
0.47	GO:0007595	lactation
0.46	GO:0051208	sequestering of calcium ion
0.46	GO:0046688	response to copper ion
0.43	GO:0006882	cellular zinc ion homeostasis
0.42	GO:0051542	elastin biosynthetic process
0.41	GO:0034760	negative regulation of iron ion transmembrane transport

0.74	GO:0032767	copper-dependent protein binding
0.71	GO:1903136	cuprous ion binding
0.68	GO:0019829	cation-transporting ATPase activity
0.52	GO:1901265	nucleoside phosphate binding
0.50	GO:0036094	small molecule binding
0.46	GO:0005375	copper ion transmembrane transporter activity
0.44	GO:0015662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
0.40	GO:0016532	superoxide dismutase copper chaperone activity
0.39	GO:0048365	Rac GTPase binding
0.38	GO:0051087	chaperone binding

0.68	GO:0016323	basolateral plasma membrane
0.67	GO:0005770	late endosome
0.66	GO:0005802	trans-Golgi network
0.66	GO:0048471	perinuclear region of cytoplasm
0.66	GO:0030140	trans-Golgi network transport vesicle
0.42	GO:0098588	bounding membrane of organelle
0.39	GO:0031526	brush border membrane
0.39	GO:0043204	perikaryon
0.39	GO:0005902	microvillus
0.39	GO:0045335	phagocytic vesicle

0.68	EC:1.97.1	GO:0051353
0.37	KEGG:R01512	GO:0004618

sp|Q04671|P_HUMAN
P protein
Search

OCA2

0.95	Oculocutaneous albinism II variant

0.59	GO:0030318	melanocyte differentiation
0.58	GO:0042438	melanin biosynthetic process
0.55	GO:0055085	transmembrane transport
0.52	GO:0007286	spermatid development
0.51	GO:0008283	cell proliferation
0.47	GO:0050935	iridophore differentiation
0.36	GO:0015828	tyrosine transport
0.36	GO:0006726	eye pigment biosynthetic process
0.33	GO:0015700	arsenite transport
0.32	GO:0015744	succinate transport

0.36	GO:0005302	L-tyrosine transmembrane transporter activity
0.34	GO:0005515	protein binding
0.33	GO:0017153	sodium:dicarboxylate symporter activity
0.33	GO:0015105	arsenite transmembrane transporter activity
0.32	GO:0015141	succinate transmembrane transporter activity
0.32	GO:0015137	citrate transmembrane transporter activity

0.57	GO:0033162	melanosome membrane
0.52	GO:0005765	lysosomal membrane
0.51	GO:0010008	endosome membrane
0.48	GO:0005789	endoplasmic reticulum membrane
0.32	GO:0005887	integral component of plasma membrane

sp|Q04695|K1C17_HUMAN
Keratin, type I cytoskeletal 17
Search

KRT17

0.92	Putative nuclear envelope protein lamin intermediate filament superfamily

0.56	GO:0042633	hair cycle
0.54	GO:0045104	intermediate filament cytoskeleton organization
0.53	GO:0031424	keratinization
0.52	GO:0048730	epidermis morphogenesis
0.52	GO:0051798	positive regulation of hair follicle development
0.52	GO:0098773	skin epidermis development
0.51	GO:0022404	molting cycle process
0.50	GO:0030307	positive regulation of cell growth
0.48	GO:0097435	supramolecular fiber organization
0.47	GO:0045727	positive regulation of translation

0.62	GO:0005198	structural molecule activity
0.56	GO:0032395	MHC class II receptor activity
0.54	GO:0042289	MHC class II protein binding
0.42	GO:1990254	keratin filament binding

0.79	GO:0005882	intermediate filament
0.40	GO:0071944	cell periphery
0.40	GO:0045178	basal part of cell
0.39	GO:0005737	cytoplasm
0.37	GO:0070062	extracellular exosome
0.37	GO:0005634	nucleus
0.36	GO:0036338	viral membrane

sp|Q04721|NOTC2_HUMAN
Neurogenic locus notch homolog protein 2
Search

0.79	Notch homolog 2

0.81	GO:0007219	Notch signaling pathway
0.70	GO:0030154	cell differentiation
0.68	GO:0007275	multicellular organism development
0.65	GO:0050793	regulation of developmental process
0.55	GO:0006355	regulation of transcription, DNA-templated
0.51	GO:0045967	negative regulation of growth rate
0.50	GO:0009653	anatomical structure morphogenesis
0.49	GO:0046849	bone remodeling
0.48	GO:0046579	positive regulation of Ras protein signal transduction
0.48	GO:0060324	face development

0.68	GO:0005509	calcium ion binding
0.62	GO:0060089	molecular transducer activity
0.36	GO:0045296	cadherin binding
0.35	GO:0042802	identical protein binding
0.35	GO:0019899	enzyme binding
0.35	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding
0.33	GO:0004871	signal transducer activity
0.33	GO:0051059	NF-kappaB binding

0.47	GO:0043235	receptor complex
0.45	GO:0009986	cell surface
0.44	GO:0005654	nucleoplasm
0.42	GO:0005887	integral component of plasma membrane
0.35	GO:0015629	actin cytoskeleton
0.35	GO:0005829	cytosol
0.34	GO:0000139	Golgi membrane
0.34	GO:0005789	endoplasmic reticulum membrane
0.34	GO:0005576	extracellular region
0.32	GO:0005929	cilium

sp|Q04724|TLE1_HUMAN
Transducin-like enhancer protein 1
Search

TLE1

0.91	Transducin like enhancer of split 1

0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.54	GO:2000811	negative regulation of anoikis
0.53	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling
0.48	GO:0051253	negative regulation of RNA metabolic process
0.48	GO:0010558	negative regulation of macromolecule biosynthetic process
0.48	GO:0031327	negative regulation of cellular biosynthetic process
0.47	GO:0010604	positive regulation of macromolecule metabolic process
0.40	GO:0016055	Wnt signaling pathway

0.53	GO:0001106	RNA polymerase II transcription corepressor activity
0.49	GO:0008134	transcription factor binding
0.48	GO:0042802	identical protein binding
0.40	GO:0003682	chromatin binding
0.39	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding

0.60	GO:0005634	nucleus
0.51	GO:0005667	transcription factor complex
0.46	GO:0005829	cytosol
0.45	GO:0031974	membrane-enclosed lumen
0.43	GO:0044446	intracellular organelle part
0.34	GO:0017053	transcriptional repressor complex

sp|Q04725|TLE2_HUMAN
Transducin-like enhancer protein 2
Search

TLE2

0.86	Enhancer of split groucho

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.40	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.38	GO:1902679	negative regulation of RNA biosynthetic process
0.37	GO:1904837	beta-catenin-TCF complex assembly
0.36	GO:0016055	Wnt signaling pathway
0.35	GO:0009887	animal organ morphogenesis
0.34	GO:0006351	transcription, DNA-templated
0.33	GO:0006468	protein phosphorylation

0.39	GO:0003714	transcription corepressor activity
0.36	GO:0016905	myosin heavy chain kinase activity
0.34	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.48	GO:0005925	focal adhesion
0.43	GO:0031974	membrane-enclosed lumen
0.40	GO:0044446	intracellular organelle part
0.37	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

0.36

EC:2.7.11.7

GO:0016905

sp|Q04726|TLE3_HUMAN
Transducin-like enhancer protein 3
Search

TLE3

0.96	Transducin like enhancer of split 3

0.55	GO:1903506	regulation of nucleic acid-templated transcription
0.55	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.37	GO:0016055	Wnt signaling pathway
0.36	GO:0007275	multicellular organism development
0.36	GO:1904837	beta-catenin-TCF complex assembly
0.35	GO:0030154	cell differentiation
0.34	GO:0007283	spermatogenesis
0.34	GO:0006351	transcription, DNA-templated
0.34	GO:0009653	anatomical structure morphogenesis

0.35

GO:0005515

protein binding

0.59	GO:0005634	nucleus
0.49	GO:0005667	transcription factor complex
0.47	GO:0031974	membrane-enclosed lumen
0.43	GO:0044446	intracellular organelle part
0.30	GO:0031224	intrinsic component of membrane

sp|Q04727|TLE4_HUMAN
Transducin-like enhancer protein 4
Search

TLE4

0.94	Transducin like enhancer of split 4

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.48	GO:1990823	response to leukemia inhibitory factor
0.46	GO:0071345	cellular response to cytokine stimulus
0.46	GO:0016055	Wnt signaling pathway
0.45	GO:1902679	negative regulation of RNA biosynthetic process
0.36	GO:1904837	beta-catenin-TCF complex assembly
0.35	GO:0001707	mesoderm formation
0.35	GO:0006351	transcription, DNA-templated

0.49	GO:0070491	repressing transcription factor binding
0.49	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
0.48	GO:0003714	transcription corepressor activity
0.46	GO:0003682	chromatin binding

0.60	GO:0005634	nucleus
0.47	GO:0005667	transcription factor complex
0.41	GO:0044446	intracellular organelle part
0.35	GO:0031974	membrane-enclosed lumen
0.35	GO:0017053	transcriptional repressor complex

sp|Q04741|EMX1_HUMAN
Homeobox protein EMX1
Search

EMX1

0.95	Empty spiracles homeobox 1

0.71	GO:0021796	cerebral cortex regionalization
0.66	GO:0030182	neuron differentiation
0.61	GO:0070445	regulation of oligodendrocyte progenitor proliferation
0.60	GO:0060019	radial glial cell differentiation
0.60	GO:0030855	epithelial cell differentiation
0.59	GO:0120036	plasma membrane bounded cell projection organization
0.59	GO:0009887	animal organ morphogenesis
0.58	GO:0048468	cell development
0.58	GO:0000902	cell morphogenesis
0.58	GO:0009790	embryo development

0.64

GO:0043565

sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.49	GO:0031974	membrane-enclosed lumen
0.45	GO:0043232	intracellular non-membrane-bounded organelle
0.44	GO:0044446	intracellular organelle part

sp|Q04743|EMX2_HUMAN
Homeobox protein EMX2
Search

EMX2

0.97	Empty spiracles homeobox 2

0.70	GO:0021796	cerebral cortex regionalization
0.66	GO:0030182	neuron differentiation
0.63	GO:0021542	dentate gyrus development
0.63	GO:0021846	cell proliferation in forebrain
0.61	GO:0021885	forebrain cell migration
0.59	GO:0009952	anterior/posterior pattern specification
0.59	GO:0072001	renal system development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0030855	epithelial cell differentiation

0.64

GO:0043565

sequence-specific DNA binding

0.61	GO:0005634	nucleus
0.42	GO:0043233	organelle lumen
0.39	GO:0043232	intracellular non-membrane-bounded organelle
0.39	GO:0044446	intracellular organelle part

sp|Q04756|HGFA_HUMAN
Hepatocyte growth factor activator
Search

HGFAC

0.97	Hepatocyte growth factor activator

0.61	GO:0006508	proteolysis
0.44	GO:0050878	regulation of body fluid levels
0.44	GO:0050817	coagulation
0.43	GO:0042060	wound healing
0.35	GO:0050819	negative regulation of coagulation
0.35	GO:0061045	negative regulation of wound healing
0.35	GO:0030514	negative regulation of BMP signaling pathway
0.34	GO:0000122	negative regulation of transcription by RNA polymerase II
0.34	GO:0006879	cellular iron ion homeostasis
0.34	GO:0045944	positive regulation of transcription by RNA polymerase II

0.69	GO:0004252	serine-type endopeptidase activity
0.45	GO:0005509	calcium ion binding
0.35	GO:0002020	protease binding
0.35	GO:0005057	signal transducer activity, downstream of receptor
0.34	GO:0030695	GTPase regulator activity
0.34	GO:0005044	scavenger receptor activity

0.63	GO:0005576	extracellular region
0.52	GO:0005791	rough endoplasmic reticulum
0.38	GO:0097180	serine protease inhibitor complex
0.35	GO:0005829	cytosol
0.33	GO:0005886	plasma membrane
0.33	GO:0001669	acrosomal vesicle
0.30	GO:0016021	integral component of membrane

0.69

GO:0004252

sp|Q04759|KPCT_HUMAN
Protein kinase C theta type
Search

PRKCQ

0.88	Protein kinase C theta type

0.63	GO:0006468	protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.61	GO:2000570	positive regulation of T-helper 2 cell activation
0.59	GO:2000318	positive regulation of T-helper 17 type immune response
0.59	GO:1904355	positive regulation of telomere capping
0.58	GO:0070233	negative regulation of T cell apoptotic process
0.58	GO:0045086	positive regulation of interleukin-2 biosynthetic process
0.58	GO:0090330	regulation of platelet aggregation
0.58	GO:0032740	positive regulation of interleukin-17 production
0.58	GO:0046627	negative regulation of insulin receptor signaling pathway

0.81	GO:0004697	protein kinase C activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0097367	carbohydrate derivative binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0008144	drug binding
0.53	GO:0046872	metal ion binding
0.36	GO:0005515	protein binding
0.34	GO:0008047	enzyme activator activity

0.57	GO:0016235	aggresome
0.56	GO:0001772	immunological synapse
0.52	GO:0005815	microtubule organizing center
0.40	GO:0048471	perinuclear region of cytoplasm
0.37	GO:0005634	nucleus
0.35	GO:0031594	neuromuscular junction
0.35	GO:0042383	sarcolemma
0.35	GO:0005829	cytosol
0.34	GO:0005911	cell-cell junction
0.33	GO:0005783	endoplasmic reticulum

0.81

GO:0004697

sp|Q04760|LGUL_HUMAN
Lactoylglutathione lyase
Search

GLO1

0.49	Lactoylglutathione lyase

0.56	GO:0030316	osteoclast differentiation
0.52	GO:0043066	negative regulation of apoptotic process
0.48	GO:0006357	regulation of transcription by RNA polymerase II
0.39	GO:0009438	methylglyoxal metabolic process
0.39	GO:0006749	glutathione metabolic process
0.36	GO:0005975	carbohydrate metabolic process
0.34	GO:0042182	ketone catabolic process
0.34	GO:0032787	monocarboxylic acid metabolic process
0.34	GO:0046185	aldehyde catabolic process
0.33	GO:1901615	organic hydroxy compound metabolic process

0.80	GO:0004462	lactoylglutathione lyase activity
0.54	GO:0046872	metal ion binding
0.33	GO:0032550	purine ribonucleoside binding
0.33	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.48	GO:0005829	cytosol
0.45	GO:0005634	nucleus
0.42	GO:0005886	plasma membrane
0.36	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

0.80	EC:4.4.1.5	GO:0004462
0.80	KEGG:R02530	GO:0004462

sp|Q04771|ACVR1_HUMAN
Activin receptor type-1
Search

ACVR1

0.61	Serine/threonine-protein kinase receptor

0.80	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
0.66	GO:0023014	signal transduction by protein phosphorylation
0.62	GO:0061445	endocardial cushion cell fate commitment
0.61	GO:0003289	atrial septum primum morphogenesis
0.61	GO:2000017	positive regulation of determination of dorsal identity
0.60	GO:0003274	endocardial cushion fusion
0.60	GO:0060923	cardiac muscle cell fate commitment
0.60	GO:1905007	positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation
0.59	GO:0003183	mitral valve morphogenesis
0.59	GO:0032926	negative regulation of activin receptor signaling pathway

0.82	GO:0004675	transmembrane receptor protein serine/threonine kinase activity
0.79	GO:0004702	signal transducer, downstream of receptor, with serine/threonine kinase activity
0.60	GO:0048185	activin binding
0.59	GO:0050431	transforming growth factor beta binding
0.56	GO:0046332	SMAD binding
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.54	GO:0008144	drug binding
0.52	GO:0042803	protein homodimerization activity

0.60	GO:0048179	activin receptor complex
0.54	GO:0045177	apical part of cell
0.39	GO:0070724	BMP receptor complex
0.37	GO:0005938	cell cortex

0.82

GO:0004675

sp|Q04828|AK1C1_HUMAN
Aldo-keto reductase family 1 member C1
Search

0.96	3-hydroxyhexobarbital dehydrogenase

0.53	GO:0055114	oxidation-reduction process
0.51	GO:0044597	daunorubicin metabolic process
0.50	GO:0071395	cellular response to jasmonic acid stimulus
0.49	GO:0044598	doxorubicin metabolic process
0.47	GO:0008202	steroid metabolic process
0.46	GO:0071798	response to prostaglandin D
0.45	GO:1900053	negative regulation of retinoic acid biosynthetic process
0.45	GO:0016488	farnesol catabolic process
0.45	GO:0071379	cellular response to prostaglandin stimulus
0.44	GO:2000224	regulation of testosterone biosynthetic process

0.54	GO:0016491	oxidoreductase activity
0.42	GO:0032052	bile acid binding
0.35	GO:0005496	steroid binding
0.35	GO:0070401	NADP+ binding
0.35	GO:0070402	NADPH binding
0.35	GO:0015125	bile acid transmembrane transporter activity
0.33	GO:0005515	protein binding

0.40	GO:0070062	extracellular exosome
0.39	GO:0005829	cytosol
0.38	GO:0005634	nucleus
0.30	GO:0016020	membrane

0.54

GO:0016491

sp|Q04837|SSBP_HUMAN
Single-stranded DNA-binding protein, mitochondrial
Search

SSBP1

0.39	Single-stranded DNA-binding protein, mitochondrial

0.66	GO:0006260	DNA replication
0.57	GO:0051096	positive regulation of helicase activity
0.56	GO:0070584	mitochondrion morphogenesis
0.37	GO:0033554	cellular response to stress
0.37	GO:0006310	DNA recombination
0.35	GO:0006986	response to unfolded protein
0.34	GO:0050909	sensory perception of taste
0.34	GO:0006468	protein phosphorylation
0.34	GO:0045944	positive regulation of transcription by RNA polymerase II
0.34	GO:0071310	cellular response to organic substance

0.73	GO:0003697	single-stranded DNA binding
0.52	GO:0003682	chromatin binding
0.35	GO:0035497	cAMP response element binding
0.34	GO:0004672	protein kinase activity
0.34	GO:0003723	RNA binding
0.34	GO:0004930	G-protein coupled receptor activity
0.33	GO:0005515	protein binding
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.55	GO:0042645	mitochondrial nucleoid
0.36	GO:0070062	extracellular exosome
0.34	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

sp|Q04844|ACHE_HUMAN
Acetylcholine receptor subunit epsilon
Search

CHRNE

0.90	Nicotinic acetylcholine receptor subunit epsilon

0.79	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.54	GO:0007271	synaptic transmission, cholinergic
0.53	GO:0035094	response to nicotine
0.52	GO:0007274	neuromuscular synaptic transmission
0.43	GO:0006936	muscle contraction
0.42	GO:0050881	musculoskeletal movement
0.41	GO:0006812	cation transport
0.37	GO:0048630	skeletal muscle tissue growth

0.82	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0099600	transmembrane receptor activity
0.54	GO:0042166	acetylcholine binding
0.35	GO:0005515	protein binding

0.79	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.54	GO:0005892	acetylcholine-gated channel complex
0.34	GO:0005654	nucleoplasm
0.34	GO:0005829	cytosol

sp|Q04864|REL_HUMAN
Proto-oncogene c-Rel
Search

REL

0.71	V-rel avian reticuloendotheliosis viral oncogene homolog

0.82	GO:0007249	I-kappaB kinase/NF-kappaB signaling
0.71	GO:0045893	positive regulation of transcription, DNA-templated
0.53	GO:0032688	negative regulation of interferon-beta production
0.52	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
0.52	GO:0051092	positive regulation of NF-kappaB transcription factor activity
0.50	GO:0006357	regulation of transcription by RNA polymerase II
0.49	GO:0006366	transcription by RNA polymerase II
0.49	GO:0038061	NIK/NF-kappaB signaling
0.48	GO:0006954	inflammatory response
0.48	GO:0010629	negative regulation of gene expression

0.61	GO:0003700	DNA binding transcription factor activity
0.54	GO:0003677	DNA binding
0.52	GO:0001067	regulatory region nucleic acid binding
0.47	GO:0003682	chromatin binding
0.43	GO:0046982	protein heterodimerization activity
0.40	GO:0071532	ankyrin repeat binding
0.39	GO:0051059	NF-kappaB binding
0.39	GO:0070491	repressing transcription factor binding
0.39	GO:0047485	protein N-terminus binding
0.39	GO:0033613	activating transcription factor binding

0.61	GO:0005634	nucleus
0.54	GO:0071159	NF-kappaB complex
0.50	GO:0033256	I-kappaB/NF-kappaB complex
0.49	GO:0005737	cytoplasm
0.39	GO:0005667	transcription factor complex
0.38	GO:0070013	intracellular organelle lumen
0.37	GO:0000785	chromatin
0.34	GO:0030430	host cell cytoplasm
0.34	GO:0042025	host cell nucleus

0.35

EC:2.7.7.19

GO:0004652

sp|Q04900|MUC24_HUMAN
Sialomucin core protein 24
Search

CD164

0.93	Sialomucin core protein 24

0.51	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
0.46	GO:0007517	muscle organ development
0.40	GO:0007162	negative regulation of cell adhesion
0.40	GO:0030097	hemopoiesis
0.39	GO:0008285	negative regulation of cell proliferation
0.38	GO:0006955	immune response
0.36	GO:0000413	protein peptidyl-prolyl isomerization
0.36	GO:0007165	signal transduction

0.38	GO:0005515	protein binding
0.36	GO:0003755	peptidyl-prolyl cis-trans isomerase activity

0.51	GO:0005764	lysosome
0.50	GO:0005768	endosome
0.45	GO:0098852	lytic vacuole membrane
0.44	GO:0044433	cytoplasmic vesicle part
0.40	GO:0005886	plasma membrane
0.37	GO:0005576	extracellular region
0.30	GO:0016021	integral component of membrane

0.36

GO:0003755

sp|Q04912|RON_HUMAN
Macrophage-stimulating protein receptor
Search

MST1R

0.94	Macrophage stimulating 1 receptor

0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.73	GO:0051897	positive regulation of protein kinase B signaling
0.71	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
0.69	GO:0043406	positive regulation of MAP kinase activity
0.66	GO:0009615	response to virus

0.76	GO:0004713	protein tyrosine kinase activity
0.72	GO:0019199	transmembrane receptor protein kinase activity
0.62	GO:0019899	enzyme binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding

0.73	GO:0097517	contractile actin filament bundle
0.72	GO:0042641	actomyosin
0.64	GO:0005773	vacuole
0.50	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.76

GO:0004713

sp|Q04917|1433F_HUMAN
14-3-3 protein eta
Search

YWHAH

0.90	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta

0.65	GO:0006713	glucocorticoid catabolic process
0.63	GO:0050774	negative regulation of dendrite morphogenesis
0.62	GO:0042921	glucocorticoid receptor signaling pathway
0.61	GO:0086010	membrane depolarization during action potential
0.60	GO:2000649	regulation of sodium ion transmembrane transporter activity
0.53	GO:0045893	positive regulation of transcription, DNA-templated
0.51	GO:0006886	intracellular protein transport
0.40	GO:0021762	substantia nigra development
0.39	GO:0055114	oxidation-reduction process
0.37	GO:1900739	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway

0.77	GO:0019904	protein domain specific binding
0.63	GO:0035259	glucocorticoid receptor binding
0.61	GO:0017080	sodium channel regulator activity
0.61	GO:0044325	ion channel binding
0.54	GO:0046982	protein heterodimerization activity
0.53	GO:0003779	actin binding
0.53	GO:0042802	identical protein binding
0.52	GO:0019899	enzyme binding
0.44	GO:0004497	monooxygenase activity
0.36	GO:0005159	insulin-like growth factor receptor binding

0.44	GO:0005886	plasma membrane
0.40	GO:0005737	cytoplasm
0.39	GO:0014704	intercalated disc
0.38	GO:0005615	extracellular space
0.38	GO:0031982	vesicle
0.38	GO:0043230	extracellular organelle
0.35	GO:0031090	organelle membrane
0.34	GO:0044446	intracellular organelle part
0.33	GO:0043231	intracellular membrane-bounded organelle

sp|Q04941|PLP2_HUMAN
Proteolipid protein 2
Search

PLP2

0.97	Proteolipid protein 2 (Colonic epithelium-enriched)

0.38	GO:0019221	cytokine-mediated signaling pathway
0.37	GO:0006935	chemotaxis
0.35	GO:0034220	ion transmembrane transport

0.69	GO:0019956	chemokine binding
0.35	GO:0015075	ion transmembrane transporter activity

0.49	GO:0005789	endoplasmic reticulum membrane
0.48	GO:0005886	plasma membrane
0.41	GO:0070062	extracellular exosome
0.30	GO:0016021	integral component of membrane

sp|Q05048|CSTF1_HUMAN
Cleavage stimulation factor subunit 1
Search

CSTF1

0.95	Cleavage stimulation factor subunit 1

0.44	GO:0006397	mRNA processing
0.40	GO:0006369	termination of RNA polymerase II transcription
0.39	GO:0031123	RNA 3'-end processing
0.38	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
0.34	GO:0042273	ribosomal large subunit biogenesis
0.34	GO:0006364	rRNA processing

0.38	GO:0003723	RNA binding
0.36	GO:0005515	protein binding

0.69

GO:0005654

nucleoplasm

sp|Q05066|SRY_HUMAN
Sex-determining region Y protein
Search

SRY

0.82	Sex-determining region Y protein (Fragment)

0.85	GO:0030238	male sex determination
0.81	GO:0007548	sex differentiation
0.72	GO:0030154	cell differentiation
0.58	GO:0006351	transcription, DNA-templated
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.41	GO:2000020	positive regulation of male gonad development
0.37	GO:0051254	positive regulation of RNA metabolic process
0.37	GO:0010557	positive regulation of macromolecule biosynthetic process

0.79	GO:0005516	calmodulin binding
0.61	GO:0003700	DNA binding transcription factor activity
0.55	GO:0003677	DNA binding
0.37	GO:0008134	transcription factor binding

0.80	GO:0016607	nuclear speck
0.34	GO:0005737	cytoplasm

sp|Q05084|ICA69_HUMAN
Islet cell autoantigen 1
Search

ICA1

0.94	Islet cell autoantigen 1

0.82	GO:0050796	regulation of insulin secretion
0.38	GO:0006836	neurotransmitter transport
0.36	GO:0043496	regulation of protein homodimerization activity
0.36	GO:0046928	regulation of neurotransmitter secretion

0.75

GO:0019904

protein domain specific binding

0.83	GO:0030667	secretory granule membrane
0.72	GO:0000139	Golgi membrane
0.57	GO:0030672	synaptic vesicle membrane
0.49	GO:0005829	cytosol
0.38	GO:0030054	cell junction
0.35	GO:0030425	dendrite
0.35	GO:0005795	Golgi stack
0.35	GO:0048471	perinuclear region of cytoplasm
0.30	GO:0016021	integral component of membrane

sp|Q05086|UBE3A_HUMAN
Ubiquitin-protein ligase E3A
Search

UBE3A

0.81	Ubiquitin-protein ligase E3A

0.73	GO:0016567	protein ubiquitination
0.71	GO:0006511	ubiquitin-dependent protein catabolic process
0.53	GO:0035037	sperm entry
0.53	GO:0050847	progesterone receptor signaling pathway
0.52	GO:0032570	response to progesterone
0.51	GO:0060736	prostate gland growth
0.51	GO:2000058	regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.50	GO:0042752	regulation of circadian rhythm
0.50	GO:0030521	androgen receptor signaling pathway
0.50	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling

0.74	GO:0061630	ubiquitin protein ligase activity
0.53	GO:0016874	ligase activity
0.47	GO:0003713	transcription coactivator activity
0.34	GO:0005515	protein binding
0.33	GO:0046872	metal ion binding
0.32	GO:1901265	nucleoside phosphate binding
0.32	GO:0036094	small molecule binding

0.44	GO:0005829	cytosol
0.41	GO:0005634	nucleus
0.35	GO:1905369	endopeptidase complex
0.34	GO:0043234	protein complex
0.30	GO:0016020	membrane

0.53

GO:0016874

sp|Q05193|DYN1_HUMAN
Dynamin-1
Search

DNM1

0.94	Dynamin 1 short form

0.72	GO:0072583	clathrin-dependent endocytosis
0.54	GO:0016185	synaptic vesicle budding from presynaptic endocytic zone membrane
0.53	GO:0051932	synaptic transmission, GABAergic
0.51	GO:0007032	endosome organization
0.50	GO:0008344	adult locomotory behavior
0.49	GO:0007605	sensory perception of sound
0.49	GO:0003374	dynamin family protein polymerization involved in mitochondrial fission
0.49	GO:1901998	toxin transport
0.49	GO:0051262	protein tetramerization
0.47	GO:0000266	mitochondrial fission

0.68	GO:0003924	GTPase activity
0.66	GO:0005525	GTP binding
0.48	GO:0019901	protein kinase binding
0.47	GO:0042802	identical protein binding
0.44	GO:0046983	protein dimerization activity
0.44	GO:0008017	microtubule binding
0.40	GO:0031749	D2 dopamine receptor binding
0.39	GO:0050998	nitric-oxide synthase binding
0.39	GO:0008022	protein C-terminus binding
0.36	GO:0032403	protein complex binding

0.51	GO:0001917	photoreceptor inner segment
0.50	GO:0043209	myelin sheath
0.47	GO:0045202	synapse
0.47	GO:0030117	membrane coat
0.46	GO:0005654	nucleoplasm
0.40	GO:0031966	mitochondrial membrane
0.39	GO:0043196	varicosity
0.38	GO:0099503	secretory vesicle
0.38	GO:0005874	microtubule
0.37	GO:0030133	transport vesicle

sp|Q05195|MAD1_HUMAN
Max dimerization protein 1
Search

MXD1

0.97	MAX dimerization protein 1

0.55	GO:0000122	negative regulation of transcription by RNA polymerase II
0.35	GO:0016070	RNA metabolic process
0.35	GO:0010467	gene expression
0.35	GO:0008283	cell proliferation
0.35	GO:0034654	nucleobase-containing compound biosynthetic process
0.34	GO:0009059	macromolecule biosynthetic process
0.34	GO:0007275	multicellular organism development
0.34	GO:0044260	cellular macromolecule metabolic process

0.66	GO:0046983	protein dimerization activity
0.56	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.55	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.54	GO:0000987	proximal promoter sequence-specific DNA binding
0.35	GO:0003714	transcription corepressor activity

0.52	GO:0000790	nuclear chromatin
0.50	GO:0005829	cytosol
0.49	GO:0005654	nucleoplasm
0.45	GO:0005739	mitochondrion
0.41	GO:0090575	RNA polymerase II transcription factor complex
0.40	GO:0005730	nucleolus
0.30	GO:0031224	intrinsic component of membrane

sp|Q05209|PTN12_HUMAN
Tyrosine-protein phosphatase non-receptor type 12
Search

PTPN12

0.65	Tyrosine-protein phosphatase

0.72	GO:0035335	peptidyl-tyrosine dephosphorylation
0.63	GO:0071364	cellular response to epidermal growth factor stimulus
0.61	GO:0042058	regulation of epidermal growth factor receptor signaling pathway
0.41	GO:0042246	tissue regeneration
0.37	GO:2000587	negative regulation of platelet-derived growth factor receptor-beta signaling pathway
0.37	GO:0038128	ERBB2 signaling pathway
0.36	GO:1901185	negative regulation of ERBB signaling pathway
0.36	GO:0071345	cellular response to cytokine stimulus

0.72	GO:0004725	protein tyrosine phosphatase activity
0.58	GO:0017124	SH3 domain binding

0.62	GO:0002102	podosome
0.51	GO:0005829	cytosol
0.38	GO:0005925	focal adhesion
0.36	GO:0042995	cell projection
0.35	GO:0005654	nucleoplasm

0.72

EC:3.1.3.48

GO:0004725

sp|Q05215|EGR4_HUMAN
Early growth response protein 4
Search

EGR4

0.97	LOW QUALITY PROTEIN: early growth response protein 4

0.56	GO:0045944	positive regulation of transcription by RNA polymerase II
0.37	GO:0006351	transcription, DNA-templated
0.37	GO:0008284	positive regulation of cell proliferation
0.36	GO:0071363	cellular response to growth factor stimulus
0.36	GO:0060280	negative regulation of ovulation
0.35	GO:1900194	negative regulation of oocyte maturation
0.35	GO:0043407	negative regulation of MAP kinase activity

0.51	GO:0003676	nucleic acid binding
0.37	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.36	GO:0046872	metal ion binding

0.38	GO:0005634	nucleus
0.34	GO:0048471	perinuclear region of cytoplasm

sp|Q05315|LEG10_HUMAN
Galectin-10
Search

0.65

Galectin

0.85	GO:0002911	regulation of lymphocyte anergy
0.85	GO:0002664	regulation of T cell tolerance induction
0.85	GO:0070231	T cell apoptotic process
0.84	GO:0002724	regulation of T cell cytokine production
0.84	GO:0046006	regulation of activated T cell proliferation
0.54	GO:0070234	positive regulation of T cell apoptotic process
0.39	GO:0007275	multicellular organism development

0.70	GO:0030246	carbohydrate binding
0.56	GO:0097153	cysteine-type endopeptidase activity involved in apoptotic process
0.49	GO:0042802	identical protein binding
0.41	GO:0004622	lysophospholipase activity

0.48

GO:0005829

cytosol

0.41

EC:3.1.1.5

GO:0004622

sp|Q05329|DCE2_HUMAN
Glutamate decarboxylase 2
Search

GAD2

0.54	Glutamate decarboxylase

0.57	GO:0019752	carboxylic acid metabolic process
0.46	GO:0042136	neurotransmitter biosynthetic process
0.43	GO:0035641	locomotory exploration behavior
0.42	GO:0035176	social behavior
0.39	GO:0042493	response to drug
0.38	GO:0016053	organic acid biosynthetic process
0.37	GO:0016054	organic acid catabolic process
0.37	GO:1901565	organonitrogen compound catabolic process
0.36	GO:1901566	organonitrogen compound biosynthetic process
0.36	GO:0007268	chemical synaptic transmission

0.68	GO:0016831	carboxy-lyase activity
0.67	GO:0030170	pyridoxal phosphate binding
0.43	GO:0016595	glutamate binding
0.40	GO:0046982	protein heterodimerization activity
0.36	GO:0047485	protein N-terminus binding
0.33	GO:0070003	threonine-type peptidase activity
0.32	GO:0004175	endopeptidase activity

0.54	GO:0030424	axon
0.52	GO:0045202	synapse
0.42	GO:0044306	neuron projection terminus
0.41	GO:0099501	exocytic vesicle membrane
0.40	GO:0005938	cell cortex
0.39	GO:0031225	anchored component of membrane
0.39	GO:0048471	perinuclear region of cytoplasm
0.39	GO:0098590	plasma membrane region
0.39	GO:0005829	cytosol
0.39	GO:0030054	cell junction

0.68

EC:4.1.1

GO:0016831

sp|Q05397|FAK1_HUMAN
Focal adhesion kinase 1
Search

PTK2

0.83	Focal ashension kinase 1

0.85	GO:0007172	signal complex assembly
0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.60	GO:0007165	signal transduction
0.44	GO:2000811	negative regulation of anoikis
0.44	GO:0010613	positive regulation of cardiac muscle hypertrophy
0.44	GO:0051964	negative regulation of synapse assembly
0.44	GO:2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
0.44	GO:0071378	cellular response to growth hormone stimulus
0.44	GO:0046621	negative regulation of organ growth
0.44	GO:0033628	regulation of cell adhesion mediated by integrin

0.77	GO:0004713	protein tyrosine kinase activity
0.64	GO:0004871	signal transducer activity
0.55	GO:0030554	adenyl nucleotide binding
0.54	GO:0097367	carbohydrate derivative binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.45	GO:0008432	JUN kinase binding
0.44	GO:0042169	SH2 domain binding
0.40	GO:0003779	actin binding
0.39	GO:0005178	integrin binding

0.81	GO:0005925	focal adhesion
0.68	GO:0005856	cytoskeleton
0.42	GO:0030027	lamellipodium
0.42	GO:0016324	apical plasma membrane
0.40	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.40	GO:0005829	cytosol
0.39	GO:0042383	sarcolemma
0.38	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0005634	nucleus
0.37	GO:0014704	intercalated disc

0.77

GO:0004713

sp|Q05469|LIPS_HUMAN
Hormone-sensitive lipase
Search

LIPE

0.86	Hormone-sensitive lipase variant B

0.83	GO:0008203	cholesterol metabolic process
0.72	GO:0016042	lipid catabolic process
0.58	GO:0046339	diacylglycerol metabolic process
0.56	GO:0006641	triglyceride metabolic process
0.53	GO:0001676	long-chain fatty acid metabolic process
0.50	GO:0072329	monocarboxylic acid catabolic process
0.42	GO:0006363	termination of RNA polymerase I transcription
0.42	GO:0006361	transcription initiation from RNA polymerase I promoter
0.36	GO:0007565	female pregnancy
0.35	GO:0019236	response to pheromone

0.75	GO:0016298	lipase activity
0.53	GO:0019901	protein kinase binding
0.50	GO:0052689	carboxylic ester hydrolase activity
0.47	GO:0017171	serine hydrolase activity
0.42	GO:0042134	rRNA primary transcript binding

0.56	GO:0005811	lipid droplet
0.50	GO:0005829	cytosol
0.43	GO:0005901	caveola
0.37	GO:0005634	nucleus
0.37	GO:0005739	mitochondrion
0.35	GO:0005615	extracellular space
0.30	GO:0016021	integral component of membrane

0.75	EC:3.1.1	GO:0016298
0.50	KEGG:R00630	GO:0052689

sp|Q05481|ZNF91_HUMAN
Zinc finger protein 91
Search

ZNF208

0.53	Zinc finger protein 91

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.44	GO:2000660	negative regulation of interleukin-1-mediated signaling pathway
0.43	GO:0043508	negative regulation of JUN kinase activity
0.43	GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway
0.43	GO:0045671	negative regulation of osteoclast differentiation
0.42	GO:1902679	negative regulation of RNA biosynthetic process
0.42	GO:2000678	negative regulation of transcription regulatory region DNA binding
0.42	GO:0007249	I-kappaB kinase/NF-kappaB signaling

0.53	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.40	GO:0031625	ubiquitin protein ligase binding
0.40	GO:0003682	chromatin binding
0.37	GO:0003700	DNA binding transcription factor activity

0.45	GO:0005622	intracellular
0.40	GO:0043227	membrane-bounded organelle
0.30	GO:0016020	membrane

sp|Q05513|KPCZ_HUMAN
Protein kinase C zeta type
Search

PRKCZ

0.84	Protein kinase C zeta type

0.62	GO:0006468	protein phosphorylation
0.60	GO:0035556	intracellular signal transduction
0.56	GO:2001181	positive regulation of interleukin-10 secretion
0.56	GO:2000667	positive regulation of interleukin-13 secretion
0.56	GO:0045630	positive regulation of T-helper 2 cell differentiation
0.56	GO:2000664	positive regulation of interleukin-5 secretion
0.56	GO:2000553	positive regulation of T-helper 2 cell cytokine production
0.54	GO:0032753	positive regulation of interleukin-4 production
0.53	GO:0046627	negative regulation of insulin receptor signaling pathway
0.53	GO:0018209	peptidyl-serine modification

0.79	GO:0004697	protein kinase C activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0032555	purine ribonucleotide binding
0.52	GO:0046872	metal ion binding
0.39	GO:0043274	phospholipase binding
0.39	GO:0071889	14-3-3 protein binding
0.39	GO:0015459	potassium channel regulator activity
0.37	GO:0019901	protein kinase binding

0.55	GO:0035748	myelin sheath abaxonal region
0.55	GO:0043203	axon hillock
0.54	GO:0045179	apical cortex
0.52	GO:0016363	nuclear matrix
0.51	GO:0016324	apical plasma membrane
0.51	GO:0005923	bicellular tight junction
0.49	GO:0005635	nuclear envelope
0.48	GO:0005815	microtubule organizing center
0.47	GO:0031982	vesicle
0.46	GO:0005829	cytosol

0.79

GO:0004697

sp|Q05516|ZBT16_HUMAN
Zinc finger and BTB domain-containing protein 16
Search

ZBTB16

0.97	Zinc finger and BTB domain-containing protein 16-A

0.63	GO:0032332	positive regulation of chondrocyte differentiation
0.62	GO:0051138	positive regulation of NK T cell differentiation
0.62	GO:0048133	male germ-line stem cell asymmetric division
0.61	GO:0045600	positive regulation of fat cell differentiation
0.61	GO:0035116	embryonic hindlimb morphogenesis
0.60	GO:0045778	positive regulation of ossification
0.60	GO:0035136	forelimb morphogenesis
0.59	GO:0051216	cartilage development
0.59	GO:0045638	negative regulation of myeloid cell differentiation
0.59	GO:0001823	mesonephros development

0.64	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding
0.61	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
0.55	GO:0042803	protein homodimerization activity
0.41	GO:0008022	protein C-terminus binding
0.40	GO:0019904	protein domain specific binding
0.35	GO:0004842	ubiquitin-protein transferase activity
0.34	GO:0046872	metal ion binding

0.60	GO:0016605	PML body
0.58	GO:0017053	transcriptional repressor complex
0.58	GO:0016607	nuclear speck
0.46	GO:0043234	protein complex
0.38	GO:0005829	cytosol
0.36	GO:0031463	Cul3-RING ubiquitin ligase complex
0.35	GO:0005886	plasma membrane
0.30	GO:0044425	membrane part

0.35

KEGG:R03876

GO:0004842

sp|Q05519|SRS11_HUMAN
Serine/arginine-rich splicing factor 11
Search

SRSF11

0.96	Serine and arginine rich splicing factor 11

0.71	GO:0008380	RNA splicing
0.35	GO:0006369	termination of RNA polymerase II transcription
0.35	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus
0.35	GO:0031124	mRNA 3'-end processing
0.34	GO:0051028	mRNA transport
0.34	GO:0006405	RNA export from nucleus

0.51	GO:0003723	RNA binding
0.33	GO:0005515	protein binding

0.54

GO:0016607

nuclear speck

sp|Q05586|NMDZ1_HUMAN
Glutamate receptor ionotropic, NMDA 1
Search

GRIN1

0.93	Glutamate ionotropic receptor NMDA type subunit 1

0.77	GO:0060079	excitatory postsynaptic potential
0.74	GO:0035235	ionotropic glutamate receptor signaling pathway
0.59	GO:0034220	ion transmembrane transport
0.54	GO:0018964	propylene metabolic process
0.53	GO:0021586	pons maturation
0.53	GO:0001661	conditioned taste aversion
0.52	GO:0060134	prepulse inhibition
0.52	GO:0043278	response to morphine
0.52	GO:0008355	olfactory learning
0.52	GO:0001975	response to amphetamine

0.79	GO:0005234	extracellularly glutamate-gated ion channel activity
0.75	GO:0004970	ionotropic glutamate receptor activity
0.52	GO:0016594	glycine binding
0.50	GO:0099094	ligand-gated cation channel activity
0.50	GO:0016595	glutamate binding
0.49	GO:1904315	transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential
0.49	GO:0022843	voltage-gated cation channel activity
0.48	GO:0005262	calcium channel activity
0.48	GO:0005516	calmodulin binding
0.46	GO:0005102	receptor binding

0.76	GO:0045211	postsynaptic membrane
0.72	GO:0030054	cell junction
0.53	GO:0017146	NMDA selective glutamate receptor complex
0.50	GO:0043197	dendritic spine
0.50	GO:0014069	postsynaptic density
0.49	GO:0008021	synaptic vesicle
0.47	GO:0009986	cell surface
0.45	GO:0005783	endoplasmic reticulum
0.40	GO:0044422	organelle part
0.38	GO:0043083	synaptic cleft

sp|Q05639|EF1A2_HUMAN
Elongation factor 1-alpha 2
Search

EEF1A2

0.45	Eukaryotic translation elongation factor 1 alpha 2

0.69	GO:0006414	translational elongation
0.54	GO:0090218	positive regulation of lipid kinase activity
0.49	GO:0043065	positive regulation of apoptotic process
0.41	GO:0071364	cellular response to epidermal growth factor stimulus
0.38	GO:0051602	response to electrical stimulus
0.36	GO:0010035	response to inorganic substance
0.35	GO:1904714	regulation of chaperone-mediated autophagy

0.70	GO:0003746	translation elongation factor activity
0.67	GO:0003924	GTPase activity
0.65	GO:0032550	purine ribonucleoside binding
0.65	GO:0019001	guanyl nucleotide binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.51	GO:0019901	protein kinase binding
0.38	GO:0005516	calmodulin binding
0.37	GO:0000049	tRNA binding

0.53	GO:0043209	myelin sheath
0.52	GO:0005853	eukaryotic translation elongation factor 1 complex
0.40	GO:0032587	ruffle membrane
0.39	GO:0030864	cortical actin cytoskeleton
0.38	GO:0005730	nucleolus
0.37	GO:0005829	cytosol
0.37	GO:0043025	neuronal cell body
0.35	GO:0098574	cytoplasmic side of lysosomal membrane
0.30	GO:0016021	integral component of membrane

sp|Q05655|KPCD_HUMAN
Protein kinase C delta type
Search

PRKCD

0.97	Protein kinase C delta type

0.68	GO:0006915	apoptotic process
0.62	GO:0006468	protein phosphorylation
0.62	GO:0035556	intracellular signal transduction
0.60	GO:2000753	positive regulation of glucosylceramide catabolic process
0.60	GO:2000755	positive regulation of sphingomyelin catabolic process
0.60	GO:1900163	positive regulation of phospholipid scramblase activity
0.59	GO:0023021	termination of signal transduction
0.59	GO:2000304	positive regulation of ceramide biosynthetic process
0.59	GO:0051490	negative regulation of filopodium assembly
0.59	GO:0032613	interleukin-10 production

0.82	GO:0004697	protein kinase C activity
0.57	GO:0043560	insulin receptor substrate binding
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0046872	metal ion binding
0.52	GO:0019901	protein kinase binding
0.50	GO:0008047	enzyme activator activity
0.38	GO:0004715	non-membrane spanning protein tyrosine kinase activity

0.67	GO:0048471	perinuclear region of cytoplasm
0.55	GO:0005634	nucleus
0.51	GO:0005911	cell-cell junction
0.49	GO:0005783	endoplasmic reticulum
0.48	GO:0005829	cytosol
0.47	GO:0070013	intracellular organelle lumen
0.42	GO:0044446	intracellular organelle part
0.42	GO:0005886	plasma membrane
0.36	GO:0070062	extracellular exosome
0.35	GO:0042582	azurophil granule

0.82

GO:0004697

sp|Q05682|CALD1_HUMAN
Caldesmon
Search

CALD1

0.88	Non-muscle caldesmon

0.83	GO:0006936	muscle contraction
0.43	GO:0006940	regulation of smooth muscle contraction
0.37	GO:1903610	regulation of calcium-dependent ATPase activity
0.36	GO:0071559	response to transforming growth factor beta
0.35	GO:0043393	regulation of protein binding
0.35	GO:0032780	negative regulation of ATPase activity
0.34	GO:0006508	proteolysis
0.34	GO:0007565	female pregnancy
0.34	GO:0051099	positive regulation of binding
0.34	GO:0051017	actin filament bundle assembly

0.85	GO:0017022	myosin binding
0.79	GO:0005516	calmodulin binding
0.74	GO:0003779	actin binding
0.54	GO:0045296	cadherin binding
0.37	GO:0005523	tropomyosin binding
0.37	GO:0004181	metallocarboxypeptidase activity
0.35	GO:0008270	zinc ion binding
0.34	GO:0044548	S100 protein binding
0.33	GO:0032403	protein complex binding

0.60	GO:0030478	actin cap
0.42	GO:0005886	plasma membrane
0.42	GO:0043231	intracellular membrane-bounded organelle
0.39	GO:0030016	myofibril
0.35	GO:0005884	actin filament
0.35	GO:0005829	cytosol
0.34	GO:0043197	dendritic spine
0.34	GO:0014069	postsynaptic density
0.34	GO:0043025	neuronal cell body
0.30	GO:0031224	intrinsic component of membrane

0.37

EC:3.4.17

GO:0004181

sp|Q05707|COEA1_HUMAN
Collagen alpha-1(XIV) chain
Search

COL14A1

0.69	Collagen, type XIV, alpha 1

0.55

GO:0070831

basement membrane assembly

0.74	GO:0005581	collagen trimer
0.52	GO:0005604	basement membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q05823|RN5A_HUMAN
2-5A-dependent ribonuclease
Search

RNASEL

0.97	2',5'-oligoisoadenylate synthetase-dependent ribonuclease L

0.68	GO:0006397	mRNA processing
0.67	GO:0090501	RNA phosphodiester bond hydrolysis
0.65	GO:2001275	positive regulation of glucose import in response to insulin stimulus
0.63	GO:0045071	negative regulation of viral genome replication
0.62	GO:0006468	protein phosphorylation
0.62	GO:0045444	fat cell differentiation
0.61	GO:0043488	regulation of mRNA stability
0.57	GO:0051607	defense response to virus
0.56	GO:0045944	positive regulation of transcription by RNA polymerase II
0.38	GO:0060337	type I interferon signaling pathway

0.67	GO:0004540	ribonuclease activity
0.62	GO:0004672	protein kinase activity
0.55	GO:0043021	ribonucleoprotein complex binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.47	GO:0003723	RNA binding
0.40	GO:0042802	identical protein binding
0.36	GO:0004519	endonuclease activity
0.35	GO:0046872	metal ion binding

0.41	GO:0016363	nuclear matrix
0.36	GO:0005759	mitochondrial matrix
0.35	GO:0005829	cytosol
0.32	GO:0001650	fibrillar center
0.32	GO:0000786	nucleosome
0.30	GO:0031224	intrinsic component of membrane

0.32

GO:0019707

sp|Q05901|ACHB3_HUMAN
Neuronal acetylcholine receptor subunit beta-3
Search

CHRNB3

0.93	Neuronal acetylcholine receptor subunit beta-3

0.79	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.45	GO:0035094	response to nicotine
0.45	GO:0007271	synaptic transmission, cholinergic
0.45	GO:0007274	neuromuscular synaptic transmission
0.39	GO:0051291	protein heterooligomerization
0.38	GO:0006812	cation transport

0.82	GO:0022848	acetylcholine-gated cation-selective channel activity
0.70	GO:0099600	transmembrane receptor activity
0.46	GO:0042166	acetylcholine binding

0.78	GO:0045211	postsynaptic membrane
0.74	GO:0030054	cell junction
0.45	GO:0005892	acetylcholine-gated channel complex
0.38	GO:0043005	neuron projection

sp|Q05923|DUS2_HUMAN
Dual specificity protein phosphatase 2
Search

DUSP2

0.72	Dual specificity protein phosphatase

0.84	GO:0000188	inactivation of MAPK activity
0.74	GO:0035335	peptidyl-tyrosine dephosphorylation
0.52	GO:0001706	endoderm formation
0.50	GO:0035970	peptidyl-threonine dephosphorylation
0.48	GO:0070373	negative regulation of ERK1 and ERK2 cascade
0.38	GO:0060795	cell fate commitment involved in formation of primary germ layer
0.38	GO:0001708	cell fate specification
0.35	GO:0042981	regulation of apoptotic process
0.34	GO:0071850	mitotic cell cycle arrest
0.34	GO:0090266	regulation of mitotic cell cycle spindle assembly checkpoint

0.85	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity
0.74	GO:0004725	protein tyrosine phosphatase activity
0.55	GO:0051019	mitogen-activated protein kinase binding
0.52	GO:0008330	protein tyrosine/threonine phosphatase activity
0.51	GO:1990439	MAP kinase serine/threonine phosphatase activity
0.33	GO:0004222	metalloendopeptidase activity
0.32	GO:0016301	kinase activity

0.51	GO:0031965	nuclear membrane
0.43	GO:0005654	nucleoplasm
0.32	GO:0005737	cytoplasm

0.85

GO:0017017

sp|Q05925|HME1_HUMAN
Homeobox protein engrailed-1
Search

EN1

0.72	Homeobox protein engrailed-1

0.70	GO:0007275	multicellular organism development
0.59	GO:0043524	negative regulation of neuron apoptotic process
0.59	GO:0061743	motor learning
0.58	GO:0042756	drinking behavior
0.57	GO:0060322	head development
0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.56	GO:0035176	social behavior
0.55	GO:0035264	multicellular organism growth

0.65	GO:0043565	sequence-specific DNA binding
0.54	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.51	GO:0001012	RNA polymerase II regulatory region DNA binding
0.49	GO:0003690	double-stranded DNA binding
0.34	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.41	GO:0043233	organelle lumen
0.39	GO:0043232	intracellular non-membrane-bounded organelle
0.38	GO:0044446	intracellular organelle part
0.34	GO:0030175	filopodium
0.34	GO:0030426	growth cone
0.34	GO:0030027	lamellipodium
0.30	GO:0016020	membrane

sp|Q05932|FOLC_HUMAN
Folylpolyglutamate synthase, mitochondrial
Search

FPGS

0.59	Folylpolyglutamate synthase

0.76	GO:0046901	tetrahydrofolylpolyglutamate biosynthetic process
0.67	GO:0006730	one-carbon metabolic process
0.51	GO:0006536	glutamate metabolic process
0.38	GO:0008283	cell proliferation
0.38	GO:0031100	animal organ regeneration
0.37	GO:0001889	liver development
0.37	GO:0007420	brain development
0.35	GO:0046655	folic acid metabolic process
0.32	GO:0006139	nucleobase-containing compound metabolic process
0.32	GO:0006544	glycine metabolic process

0.76	GO:0004326	tetrahydrofolylpolyglutamate synthase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0032553	ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.49	GO:0008841	dihydrofolate synthase activity
0.35	GO:0046872	metal ion binding

0.46	GO:0005739	mitochondrion
0.37	GO:0031974	membrane-enclosed lumen
0.36	GO:0019866	organelle inner membrane
0.36	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.76

EC:6.3.2.17

GO:0004326

sp|Q05940|VMAT2_HUMAN
Synaptic vesicular amine transporter
Search

SLC18A2

0.96	Solute carrier family 18 (vesicular monoamine transporter), member 2

0.70	GO:0001975	response to amphetamine
0.69	GO:0007626	locomotory behavior
0.64	GO:0006855	drug transmembrane transport
0.63	GO:0009791	post-embryonic development
0.58	GO:0015842	aminergic neurotransmitter loading into synaptic vesicle
0.57	GO:0006837	serotonin transport
0.39	GO:0035864	response to potassium ion

0.63	GO:0015238	drug transmembrane transporter activity
0.58	GO:0015222	serotonin transmembrane transporter activity
0.32	GO:0097159	organic cyclic compound binding

0.52	GO:0098793	presynapse
0.46	GO:0005887	integral component of plasma membrane
0.39	GO:0042583	chromaffin granule

sp|Q05952|STP2_HUMAN
Nuclear transition protein 2
Search

TNP2

0.97	Nuclear transition protein 2

0.80	GO:0007283	spermatogenesis
0.69	GO:0030154	cell differentiation
0.68	GO:0007275	multicellular organism development
0.63	GO:0010954	positive regulation of protein processing
0.61	GO:0007341	penetration of zona pellucida
0.60	GO:0043486	histone exchange
0.59	GO:0006997	nucleus organization
0.58	GO:0007340	acrosome reaction
0.57	GO:0022412	cellular process involved in reproduction in multicellular organism
0.56	GO:0003006	developmental process involved in reproduction

0.55	GO:0003677	DNA binding
0.52	GO:0046872	metal ion binding
0.37	GO:0005515	protein binding

0.75	GO:0000786	nucleosome
0.61	GO:0005634	nucleus
0.51	GO:0031974	membrane-enclosed lumen

sp|Q05996|ZP2_HUMAN
Zona pellucida sperm-binding protein 2
Search

ZP2

0.96	Zona pellucida protein subunit A

0.69	GO:0060468	prevention of polyspermy
0.65	GO:0007339	binding of sperm to zona pellucida
0.38	GO:0002455	humoral immune response mediated by circulating immunoglobulin
0.37	GO:0060046	regulation of acrosome reaction
0.30	GO:0007165	signal transduction

0.67	GO:0032190	acrosin binding
0.56	GO:0042802	identical protein binding
0.30	GO:0004872	receptor activity
0.30	GO:0004871	signal transducer activity

0.65	GO:0005771	multivesicular body
0.58	GO:0005576	extracellular region
0.55	GO:0005783	endoplasmic reticulum
0.46	GO:0005886	plasma membrane
0.37	GO:0016234	inclusion body
0.35	GO:0042597	periplasmic space
0.33	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

sp|Q05BQ5|MBTD1_HUMAN
MBT domain-containing protein 1
Search

MBTD1

0.96	LOW QUALITY PROTEIN: MBT domain-containing protein 1

0.57	GO:1903506	regulation of nucleic acid-templated transcription
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.56	GO:0010468	regulation of gene expression
0.51	GO:0048706	embryonic skeletal system development
0.37	GO:0016569	covalent chromatin modification
0.35	GO:0006351	transcription, DNA-templated

0.62	GO:0008270	zinc ion binding
0.52	GO:0140034	methylation-dependent protein binding
0.50	GO:0042393	histone binding

0.61	GO:0005634	nucleus
0.30	GO:0016020	membrane

sp|Q05BU3|F86JP_HUMAN
Putative protein FAM86JP
Search

0.30	Eukaryotic elongation factor 2 lysine methyltransferase

sp|Q05BV3|EMAL5_HUMAN
Echinoderm microtubule-associated protein-like 5
Search

EML5

0.71	Echinoderm microtubule associated protein like 5

0.74	GO:0008017	microtubule binding
0.30	GO:0003824	catalytic activity

0.71	GO:0015630	microtubule cytoskeleton
0.30	GO:0070062	extracellular exosome
0.30	GO:0044430	cytoskeletal part
0.30	GO:0005737	cytoplasm
0.30	GO:0099081	supramolecular polymer

sp|Q05C16|LRC63_HUMAN
Leucine-rich repeat-containing protein 63
Search

LRRC63

0.97	Leucine-rich repeat-containing protein 63

0.66	GO:0010976	positive regulation of neuron projection development
0.51	GO:0007165	signal transduction

0.62	GO:0043005	neuron projection
0.47	GO:0005886	plasma membrane
0.43	GO:0005737	cytoplasm
0.30	GO:0044425	membrane part

sp|Q05D32|CTSL2_HUMAN
CTD small phosphatase-like protein 2
Search

CTDSPL2

0.90	CTD small phosphatase

0.67	GO:0016311	dephosphorylation
0.53	GO:0046827	positive regulation of protein export from nucleus
0.53	GO:0030514	negative regulation of BMP signaling pathway
0.45	GO:0036211	protein modification process
0.43	GO:0044267	cellular protein metabolic process
0.34	GO:0040012	regulation of locomotion
0.33	GO:0043043	peptide biosynthetic process
0.32	GO:0010467	gene expression
0.32	GO:0009059	macromolecule biosynthetic process

0.68	GO:0016791	phosphatase activity
0.44	GO:0140096	catalytic activity, acting on a protein
0.34	GO:0003743	translation initiation factor activity

0.48	GO:0005654	nucleoplasm
0.34	GO:0005852	eukaryotic translation initiation factor 3 complex
0.30	GO:0031224	intrinsic component of membrane

0.68

EC:3.1.3 EC:3.1.3.41

GO:0016791

sp|Q05D60|DEUP1_HUMAN
Deuterosome assembly protein 1
Search

DEUP1

0.97	Deuterosome assembly protein 1

0.86	GO:0098535	de novo centriole assembly involved in multi-ciliated epithelial cell differentiation
0.57	GO:0007099	centriole replication
0.42	GO:0030030	cell projection organization

0.60

GO:0042802

identical protein binding

0.86	GO:0098536	deuterosome
0.56	GO:0005814	centriole
0.30	GO:0031224	intrinsic component of membrane

sp|Q05DH4|F16A1_HUMAN
Protein FAM160A1
Search

sp|Q06033|ITIH3_HUMAN
Inter-alpha-trypsin inhibitor heavy chain H3
Search

ITIH3

0.95	Inter-alpha-trypsin inhibitor heavy chain 3

0.85	GO:0030212	hyaluronan metabolic process
0.76	GO:0010951	negative regulation of endopeptidase activity
0.36	GO:0002576	platelet degranulation
0.34	GO:0006953	acute-phase response
0.33	GO:0034097	response to cytokine

0.78	GO:0004867	serine-type endopeptidase inhibitor activity
0.33	GO:0005509	calcium ion binding

0.41	GO:0005576	extracellular region
0.37	GO:0031982	vesicle
0.34	GO:0012505	endomembrane system
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.33	GO:0044444	cytoplasmic part
0.30	GO:0031224	intrinsic component of membrane

sp|Q06055|AT5G2_HUMAN
ATP synthase F(0) complex subunit C2, mitochondrial
Search

0.87	ATP synthase lipid-binding protein, mitochondrial

0.76	GO:0015991	ATP hydrolysis coupled proton transport
0.70	GO:0015985	energy coupled proton transport, down electrochemical gradient
0.70	GO:0006754	ATP biosynthetic process
0.38	GO:0045471	response to ethanol
0.36	GO:0042407	cristae formation
0.35	GO:0006839	mitochondrial transport
0.34	GO:0046907	intracellular transport
0.34	GO:0007568	aging
0.33	GO:0055114	oxidation-reduction process

0.71	GO:0008289	lipid binding
0.63	GO:0015078	hydrogen ion transmembrane transporter activity
0.44	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
0.44	GO:0019829	cation-transporting ATPase activity
0.35	GO:0004450	isocitrate dehydrogenase (NADP+) activity
0.35	GO:0015662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
0.33	GO:0005515	protein binding

0.72	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)
0.47	GO:0005753	mitochondrial proton-transporting ATP synthase complex
0.34	GO:0005741	mitochondrial outer membrane
0.30	GO:0031224	intrinsic component of membrane

0.35

EC:1.1.1.42

GO:0004450

sp|Q06124|PTN11_HUMAN
Tyrosine-protein phosphatase non-receptor type 11
Search

PTPN11

0.61	Tyrosine-protein phosphatase non-receptor type

0.73	GO:0035335	peptidyl-tyrosine dephosphorylation
0.60	GO:0051463	negative regulation of cortisol secretion
0.60	GO:0060125	negative regulation of growth hormone secretion
0.59	GO:0061582	intestinal epithelial cell migration
0.59	GO:0033277	abortive mitotic cell cycle
0.58	GO:0036302	atrioventricular canal development
0.58	GO:2001275	positive regulation of glucose import in response to insulin stimulus
0.58	GO:0033629	negative regulation of cell adhesion mediated by integrin
0.58	GO:0060020	Bergmann glial cell differentiation
0.57	GO:0071364	cellular response to epidermal growth factor stimulus

0.73	GO:0004725	protein tyrosine phosphatase activity
0.57	GO:0005158	insulin receptor binding
0.57	GO:0051428	peptide hormone receptor binding
0.56	GO:0005070	SH3/SH2 adaptor activity
0.55	GO:0030971	receptor tyrosine kinase binding
0.53	GO:0050839	cell adhesion molecule binding
0.40	GO:0031748	D1 dopamine receptor binding
0.40	GO:0043274	phospholipase binding
0.39	GO:0043560	insulin receptor substrate binding
0.37	GO:0019904	protein domain specific binding

0.45	GO:0005737	cytoplasm
0.45	GO:0005634	nucleus
0.44	GO:0043234	protein complex
0.34	GO:0070013	intracellular organelle lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.73	EC:3.1.3.48	GO:0004725
0.36	KEGG:R04545	GO:0046934

sp|Q06136|KDSR_HUMAN
3-ketodihydrosphingosine reductase
Search

KDSR

0.95	3-ketodihydrosphingosine reductase

0.66	GO:0006666	3-keto-sphinganine metabolic process
0.60	GO:0030148	sphingolipid biosynthetic process
0.50	GO:0055114	oxidation-reduction process

0.66

GO:0047560

3-dehydrosphinganine reductase activity

0.53	GO:0005783	endoplasmic reticulum
0.38	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network
0.37	GO:0031984	organelle subcompartment
0.35	GO:0005615	extracellular space
0.30	GO:0031224	intrinsic component of membrane

0.66	EC:1.1.1.102	GO:0047560
0.66	KEGG:R02978	GO:0047560

sp|Q06141|REG3A_HUMAN
Regenerating islet-derived protein 3-alpha
Search

0.97	Pancreatic beta cell growth factor

0.70	GO:0044278	cell wall disruption in other organism
0.65	GO:0019730	antimicrobial humoral response
0.63	GO:0045617	negative regulation of keratinocyte differentiation
0.63	GO:0010838	positive regulation of keratinocyte proliferation
0.61	GO:0051715	cytolysis in other organism
0.60	GO:0090303	positive regulation of wound healing
0.59	GO:0050830	defense response to Gram-positive bacterium
0.58	GO:0006953	acute-phase response
0.57	GO:0050829	defense response to Gram-negative bacterium
0.51	GO:0002755	MyD88-dependent toll-like receptor signaling pathway

0.64	GO:0070492	oligosaccharide binding
0.58	GO:0042834	peptidoglycan binding
0.54	GO:0042802	identical protein binding
0.42	GO:0008083	growth factor activity
0.39	GO:0019838	growth factor binding
0.37	GO:2001065	mannan binding
0.36	GO:0008201	heparin binding

0.52	GO:0005576	extracellular region
0.49	GO:0030141	secretory granule
0.41	GO:0044216	other organism cell
0.39	GO:0045177	apical part of cell
0.35	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

sp|Q06187|BTK_HUMAN
Tyrosine-protein kinase BTK
Search

BTK

0.60	Tyrosine-protein kinase

0.76	GO:0018108	peptidyl-tyrosine phosphorylation
0.61	GO:0002344	B cell affinity maturation
0.61	GO:0098761	cellular response to interleukin-7
0.61	GO:0035556	intracellular signal transduction
0.59	GO:0030889	negative regulation of B cell proliferation
0.55	GO:0001818	negative regulation of cytokine production
0.55	GO:0048469	cell maturation
0.49	GO:0046777	protein autophosphorylation
0.46	GO:0045087	innate immune response
0.46	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway

0.80	GO:0004715	non-membrane spanning protein tyrosine kinase activity
0.59	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding
0.54	GO:0032559	adenyl ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.52	GO:0042802	identical protein binding
0.44	GO:0005102	receptor binding
0.34	GO:0046872	metal ion binding

0.56	GO:0045121	membrane raft
0.50	GO:0031410	cytoplasmic vesicle
0.50	GO:0005829	cytosol
0.47	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.45	GO:0005634	nucleus
0.40	GO:0042629	mast cell granule
0.38	GO:0048471	perinuclear region of cytoplasm
0.34	GO:0005739	mitochondrion
0.34	GO:0032587	ruffle membrane
0.33	GO:0043233	organelle lumen

0.80

EC:2.7.10.2

GO:0004715

sp|Q06190|P2R3A_HUMAN
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha
Search

PPP2R3A

0.91	Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha

0.44	GO:0090249	regulation of cell motility involved in somitogenic axis elongation
0.42	GO:0007525	somatic muscle development
0.41	GO:0090263	positive regulation of canonical Wnt signaling pathway
0.41	GO:0001754	eye photoreceptor cell differentiation
0.40	GO:0090090	negative regulation of canonical Wnt signaling pathway
0.39	GO:0045732	positive regulation of protein catabolic process
0.39	GO:0090244	Wnt signaling pathway involved in somitogenesis
0.37	GO:0006470	protein dephosphorylation
0.36	GO:0036342	post-anal tail morphogenesis
0.36	GO:0043666	regulation of phosphoprotein phosphatase activity

0.68	GO:0005509	calcium ion binding
0.39	GO:0030674	protein binding, bridging
0.36	GO:0019888	protein phosphatase regulator activity
0.35	GO:0004721	phosphoprotein phosphatase activity

0.57

GO:0000159

protein phosphatase type 2A complex

0.35

GO:0004721

sp|Q06203|PUR1_HUMAN
Amidophosphoribosyltransferase
Search

PPAT

0.52	Amidophosphoribosyltransferase

0.73	GO:0009113	purine nucleobase biosynthetic process
0.65	GO:0006189	'de novo' IMP biosynthetic process
0.65	GO:0009116	nucleoside metabolic process
0.40	GO:0007595	lactation
0.40	GO:0031100	animal organ regeneration
0.40	GO:0060135	maternal process involved in female pregnancy
0.40	GO:0051289	protein homotetramerization
0.40	GO:0032869	cellular response to insulin stimulus
0.39	GO:0000082	G1/S transition of mitotic cell cycle
0.39	GO:0006543	glutamine catabolic process

0.77	GO:0004044	amidophosphoribosyltransferase activity
0.61	GO:0051536	iron-sulfur cluster binding
0.52	GO:0046872	metal ion binding

0.35

GO:0005829

cytosol

0.77	EC:2.4.2.14	GO:0004044
0.77	KEGG:R01072	GO:0004044

sp|Q06210|GFPT1_HUMAN
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1
Search

GFPT1

0.77	Glucosamine--fructose-6-phosphate aminotransferase

0.59	GO:1901137	carbohydrate derivative biosynthetic process
0.53	GO:0032922	circadian regulation of gene expression
0.45	GO:0006047	UDP-N-acetylglucosamine metabolic process
0.45	GO:0006002	fructose 6-phosphate metabolic process
0.44	GO:0043413	macromolecule glycosylation
0.44	GO:0009100	glycoprotein metabolic process
0.39	GO:0036211	protein modification process
0.38	GO:0044267	cellular protein metabolic process
0.37	GO:1901566	organonitrogen compound biosynthetic process
0.37	GO:0009059	macromolecule biosynthetic process

0.75	GO:0004360	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
0.54	GO:0097367	carbohydrate derivative binding
0.34	GO:0016597	amino acid binding
0.34	GO:0051536	iron-sulfur cluster binding
0.34	GO:0030246	carbohydrate binding
0.33	GO:0005506	iron ion binding

0.36	GO:0070062	extracellular exosome
0.33	GO:0005829	cytosol
0.30	GO:0016020	membrane

0.75	EC:2.6.1.16	GO:0004360
0.75	KEGG:R00768	GO:0004360

sp|Q06250|WIT1_HUMAN
Putative Wilms tumor upstream neighbor 1 gene protein
Search

0.30	Putative Wilms tumor upstream neighbor 1 gene protein

0.63

GO:0005515

protein binding

sp|Q06265|EXOS9_HUMAN
Exosome complex component RRP45
Search

EXOSC9

0.87	Exosome component 9

0.61	GO:0006396	RNA processing
0.58	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
0.58	GO:0071035	nuclear polyadenylation-dependent rRNA catabolic process
0.58	GO:0071028	nuclear mRNA surveillance
0.55	GO:0030307	positive regulation of cell growth
0.49	GO:0071047	polyadenylation-dependent mRNA catabolic process
0.49	GO:0071038	nuclear polyadenylation-dependent tRNA catabolic process
0.48	GO:0034427	nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'
0.47	GO:0016073	snRNA metabolic process
0.45	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic

0.59	GO:0017091	AU-rich element binding
0.42	GO:0004527	exonuclease activity
0.39	GO:0001102	RNA polymerase II activating transcription factor binding
0.35	GO:0004540	ribonuclease activity

0.77	GO:0000178	exosome (RNase complex)
0.51	GO:0005730	nucleolus
0.51	GO:0000228	nuclear chromosome
0.49	GO:0005654	nucleoplasm
0.40	GO:0005737	cytoplasm
0.37	GO:0070062	extracellular exosome
0.30	GO:0031224	intrinsic component of membrane

sp|Q06278|AOXA_HUMAN
Aldehyde oxidase
Search

AOX1

0.53	Aldehyde oxidase

0.60	GO:0022900	electron transport chain
0.51	GO:0009115	xanthine catabolic process
0.44	GO:0017144	drug metabolic process
0.34	GO:0006805	xenobiotic metabolic process
0.34	GO:0072524	pyridine-containing compound metabolic process
0.34	GO:0006766	vitamin metabolic process

0.70	GO:0051537	2 iron, 2 sulfur cluster binding
0.67	GO:0051287	NAD binding
0.66	GO:0043546	molybdopterin cofactor binding
0.66	GO:0050660	flavin adenine dinucleotide binding
0.65	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors
0.62	GO:0005506	iron ion binding
0.61	GO:0009055	electron transfer activity
0.61	GO:0004031	aldehyde oxidase activity
0.51	GO:0042803	protein homodimerization activity
0.48	GO:0004854	xanthine dehydrogenase activity

0.50	GO:0005829	cytosol
0.36	GO:0070062	extracellular exosome

0.65

EC:1.1

GO:0016614

sp|Q06323|PSME1_HUMAN
Proteasome activator complex subunit 1
Search

PSME1

0.97	Proteasome activator complex subunit 1

0.53	GO:0010950	positive regulation of endopeptidase activity
0.52	GO:0019884	antigen processing and presentation of exogenous antigen
0.48	GO:2000045	regulation of G1/S transition of mitotic cell cycle
0.47	GO:0061136	regulation of proteasomal protein catabolic process
0.37	GO:0006508	proteolysis
0.36	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
0.36	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
0.36	GO:0002223	stimulatory C-type lectin receptor signaling pathway
0.35	GO:0038095	Fc-epsilon receptor signaling pathway
0.35	GO:1902036	regulation of hematopoietic stem cell differentiation

0.56	GO:0061133	endopeptidase activator activity
0.36	GO:0008233	peptidase activity
0.35	GO:0005515	protein binding
0.33	GO:0004613	phosphoenolpyruvate carboxykinase (GTP) activity
0.32	GO:0005525	GTP binding
0.32	GO:0016301	kinase activity

0.85	GO:0008537	proteasome activator complex
0.36	GO:0005737	cytoplasm
0.36	GO:0070062	extracellular exosome
0.34	GO:0005654	nucleoplasm
0.30	GO:0016020	membrane

0.36

GO:0008233

sp|Q06330|SUH_HUMAN
Recombining binding protein suppressor of hairless
Search

RBPJ

0.93	Recombination signal binding protein for immunoglobulin kappa J region b

0.73	GO:0072148	epithelial cell fate commitment
0.71	GO:0006357	regulation of transcription by RNA polymerase II
0.70	GO:0060840	artery development
0.70	GO:0001756	somitogenesis
0.68	GO:0035270	endocrine system development
0.68	GO:1905068	positive regulation of canonical Wnt signaling pathway involved in heart development
0.68	GO:1901189	positive regulation of ephrin receptor signaling pathway
0.68	GO:0060485	mesenchyme development
0.67	GO:1901295	regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment
0.67	GO:0001525	angiogenesis

0.80	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.80	GO:0000982	transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.65	GO:0001103	RNA polymerase II repressing transcription factor binding
0.62	GO:0047485	protein N-terminus binding
0.61	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.57	GO:0003682	chromatin binding
0.38	GO:0032403	protein complex binding

0.68	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex
0.61	GO:0005634	nucleus
0.61	GO:0017053	transcriptional repressor complex
0.56	GO:0005667	transcription factor complex
0.52	GO:0070013	intracellular organelle lumen
0.48	GO:0043232	intracellular non-membrane-bounded organelle
0.47	GO:0044446	intracellular organelle part
0.41	GO:0005737	cytoplasm
0.38	GO:0032993	protein-DNA complex

sp|Q06413|MEF2C_HUMAN
Myocyte-specific enhancer factor 2C
Search

MEF2C

0.96	Myocyte-specific enhancer factor 2C

0.74	GO:0045944	positive regulation of transcription by RNA polymerase II
0.57	GO:0006351	transcription, DNA-templated
0.55	GO:0071374	cellular response to parathyroid hormone stimulus
0.55	GO:2001016	positive regulation of skeletal muscle cell differentiation
0.54	GO:0003185	sinoatrial valve morphogenesis
0.54	GO:0003138	primary heart field specification
0.54	GO:2000987	positive regulation of behavioral fear response
0.54	GO:2000727	positive regulation of cardiac muscle cell differentiation
0.53	GO:2000111	positive regulation of macrophage apoptotic process
0.53	GO:0035984	cellular response to trichostatin A

0.76	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.67	GO:0046983	protein dimerization activity
0.53	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding
0.52	GO:0003680	AT DNA binding
0.51	GO:0033613	activating transcription factor binding
0.51	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.51	GO:0071837	HMG box domain binding
0.50	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding
0.49	GO:0001158	enhancer sequence-specific DNA binding
0.49	GO:0042826	histone deacetylase binding

0.61	GO:0005634	nucleus
0.47	GO:0070013	intracellular organelle lumen
0.46	GO:0098794	postsynapse
0.42	GO:0044446	intracellular organelle part
0.42	GO:0043234	protein complex
0.41	GO:0016528	sarcoplasm
0.35	GO:0030017	sarcomere

sp|Q06416|P5F1B_HUMAN
Putative POU domain, class 5, transcription factor 1B
Search

POU5F1

0.53	POU domain, class 5, transcription factor 1

0.56	GO:2001141	regulation of RNA biosynthetic process
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.55	GO:0006351	transcription, DNA-templated
0.47	GO:0001711	endodermal cell fate commitment
0.46	GO:0009786	regulation of asymmetric cell division
0.46	GO:0001712	ectodermal cell fate commitment
0.46	GO:0010604	positive regulation of macromolecule metabolic process
0.46	GO:0045955	negative regulation of calcium ion-dependent exocytosis
0.45	GO:0001829	trophectodermal cell differentiation

0.61	GO:0043565	sequence-specific DNA binding
0.60	GO:0003700	DNA binding transcription factor activity
0.50	GO:0035326	enhancer binding
0.50	GO:0019955	cytokine binding
0.46	GO:0003690	double-stranded DNA binding
0.46	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding
0.44	GO:0031625	ubiquitin protein ligase binding
0.44	GO:0031490	chromatin DNA binding
0.43	GO:0003714	transcription corepressor activity
0.42	GO:0001012	RNA polymerase II regulatory region DNA binding

0.60	GO:0005634	nucleus
0.45	GO:0000785	chromatin
0.45	GO:0070013	intracellular organelle lumen
0.43	GO:0017053	transcriptional repressor complex
0.42	GO:0005667	transcription factor complex
0.40	GO:0005829	cytosol
0.37	GO:0005739	mitochondrion

sp|Q06418|TYRO3_HUMAN
Tyrosine-protein kinase receptor TYRO3
Search

TYRO3

0.95	Tyrosine-protein kinase receptor TYRO3

0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.67	GO:0070050	neuron cellular homeostasis
0.66	GO:0060068	vagina development
0.66	GO:0001779	natural killer cell differentiation
0.66	GO:0034122	negative regulation of toll-like receptor signaling pathway
0.66	GO:0070527	platelet aggregation
0.66	GO:0043491	protein kinase B signaling
0.66	GO:0043277	apoptotic cell clearance
0.65	GO:0034446	substrate adhesion-dependent cell spreading
0.65	GO:0021885	forebrain cell migration

0.77	GO:0004713	protein tyrosine kinase activity
0.68	GO:0043548	phosphatidylinositol 3-kinase binding
0.56	GO:0046982	protein heterodimerization activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.44	GO:0019199	transmembrane receptor protein kinase activity
0.38	GO:0104005	hijacked molecular function
0.36	GO:0005057	signal transducer activity, downstream of receptor

0.50	GO:0005635	nuclear envelope
0.49	GO:0005789	endoplasmic reticulum membrane
0.37	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

0.77

GO:0004713

sp|Q06432|CCG1_HUMAN
Voltage-dependent calcium channel gamma-1 subunit
Search

CACNG1

0.46	Voltage-dependent calcium channel gamma-1 subunit

0.76	GO:0070588	calcium ion transmembrane transport
0.75	GO:0034765	regulation of ion transmembrane transport
0.61	GO:0070296	sarcoplasmic reticulum calcium ion transport
0.36	GO:0061337	cardiac conduction
0.35	GO:0006936	muscle contraction

0.80	GO:0005245	voltage-gated calcium channel activity
0.34	GO:0005515	protein binding

0.80	GO:0005891	voltage-gated calcium channel complex
0.35	GO:0030315	T-tubule

sp|Q06455|MTG8_HUMAN
Protein CBFA2T1
Search

RUNX1T1

0.97	Runt-related transcription factor 1 translocated to, 1 (Cyclin D-related)

0.72	GO:0045892	negative regulation of transcription, DNA-templated
0.39	GO:0045599	negative regulation of fat cell differentiation
0.38	GO:0045444	fat cell differentiation
0.37	GO:0051101	regulation of DNA binding
0.35	GO:0010977	negative regulation of neuron projection development
0.33	GO:0006351	transcription, DNA-templated
0.33	GO:0006091	generation of precursor metabolites and energy

0.81	GO:0003714	transcription corepressor activity
0.61	GO:0003700	DNA binding transcription factor activity
0.36	GO:0042803	protein homodimerization activity
0.34	GO:0003677	DNA binding
0.33	GO:0046872	metal ion binding

0.46	GO:0005654	nucleoplasm
0.39	GO:0016363	nuclear matrix
0.34	GO:0017053	transcriptional repressor complex

sp|Q06481|APLP2_HUMAN
Amyloid-like protein 2
Search

APLP2

0.88	Amyloid beta precursor like protein 2

0.74

GO:0010951

negative regulation of endopeptidase activity

0.82	GO:0008201	heparin binding
0.76	GO:0004867	serine-type endopeptidase inhibitor activity
0.58	GO:0046914	transition metal ion binding
0.54	GO:0042802	identical protein binding

0.47	GO:0005634	nucleus
0.30	GO:0044425	membrane part

sp|Q06495|NPT2A_HUMAN
Sodium-dependent phosphate transport protein 2A
Search

SLC34A1

0.85	Renal type IIb sodium-dependent phosphate cotransporter

0.81	GO:0044341	sodium-dependent phosphate transport
0.61	GO:0072506	trivalent inorganic anion homeostasis
0.61	GO:0072505	divalent inorganic anion homeostasis
0.61	GO:0055083	monovalent inorganic anion homeostasis
0.59	GO:0010288	response to lead ion
0.55	GO:0046686	response to cadmium ion
0.53	GO:0046689	response to mercury ion
0.53	GO:0030002	cellular anion homeostasis
0.53	GO:0035725	sodium ion transmembrane transport
0.52	GO:0035435	phosphate ion transmembrane transport

0.81	GO:0015321	sodium-dependent phosphate transmembrane transporter activity
0.59	GO:0005436	sodium:phosphate symporter activity
0.47	GO:0031402	sodium ion binding
0.46	GO:0042301	phosphate ion binding
0.39	GO:0030165	PDZ domain binding
0.37	GO:0042803	protein homodimerization activity
0.37	GO:0032403	protein complex binding
0.35	GO:0005057	signal transducer activity, downstream of receptor
0.34	GO:0004714	transmembrane receptor protein tyrosine kinase activity
0.32	GO:0030554	adenyl nucleotide binding

0.62	GO:0016324	apical plasma membrane
0.56	GO:0005903	brush border
0.54	GO:0072686	mitotic spindle
0.54	GO:0016607	nuclear speck
0.47	GO:0031982	vesicle
0.40	GO:0045203	integral component of cell outer membrane
0.40	GO:0031253	cell projection membrane
0.38	GO:0098857	membrane microdomain
0.38	GO:0048471	perinuclear region of cytoplasm
0.38	GO:0009986	cell surface

0.34

EC:2.7.10.1

GO:0004714

sp|Q06520|ST2A1_HUMAN
Bile salt sulfotransferase
Search

0.56	Bile salt sulfotransferase

0.57	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process
0.53	GO:0008202	steroid metabolic process
0.49	GO:0045606	positive regulation of epidermal cell differentiation
0.49	GO:0006068	ethanol catabolic process
0.47	GO:0051923	sulfation
0.46	GO:0008285	negative regulation of cell proliferation
0.45	GO:1902652	secondary alcohol metabolic process
0.45	GO:0000103	sulfate assimilation
0.40	GO:0071305	cellular response to vitamin D
0.40	GO:0017085	response to insecticide

0.78	GO:0008146	sulfotransferase activity
0.50	GO:1990239	steroid hormone binding
0.47	GO:0015485	cholesterol binding
0.40	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding
0.37	GO:0003676	nucleic acid binding
0.34	GO:0005515	protein binding
0.34	GO:0008144	drug binding
0.32	GO:0003735	structural constituent of ribosome

0.49	GO:0005829	cytosol
0.38	GO:0043231	intracellular membrane-bounded organelle
0.35	GO:0070062	extracellular exosome
0.35	GO:0012505	endomembrane system
0.32	GO:0005840	ribosome

0.78

EC:2.8.2

GO:0008146

sp|Q06546|GABPA_HUMAN
GA-binding protein alpha chain
Search

GABPA

0.96	GA binding protein transcription factor alpha subunit

0.70	GO:0045653	negative regulation of megakaryocyte differentiation
0.70	GO:1903351	cellular response to dopamine
0.60	GO:0000122	negative regulation of transcription by RNA polymerase II
0.60	GO:0006366	transcription by RNA polymerase II
0.60	GO:0045944	positive regulation of transcription by RNA polymerase II
0.58	GO:0001701	in utero embryonic development
0.49	GO:0030154	cell differentiation

0.66	GO:0033613	activating transcription factor binding
0.65	GO:0043565	sequence-specific DNA binding
0.64	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.61	GO:0001012	RNA polymerase II regulatory region DNA binding
0.60	GO:0003682	chromatin binding
0.59	GO:0046982	protein heterodimerization activity
0.57	GO:0003690	double-stranded DNA binding

0.61	GO:0005634	nucleus
0.57	GO:0000785	chromatin
0.55	GO:0031974	membrane-enclosed lumen

sp|Q06547|GABP1_HUMAN
GA-binding protein subunit beta-1
Search

GABPB1

0.95	GA-binding protein subunit beta-1

0.72	GO:0045944	positive regulation of transcription by RNA polymerase II
0.50	GO:0006351	transcription, DNA-templated
0.50	GO:0007005	mitochondrion organization

0.73	GO:0044212	transcription regulatory region DNA binding
0.67	GO:0046982	protein heterodimerization activity
0.53	GO:0003700	DNA binding transcription factor activity

0.74	GO:0036464	cytoplasmic ribonucleoprotein granule
0.66	GO:0005654	nucleoplasm

sp|Q06587|RING1_HUMAN
E3 ubiquitin-protein ligase RING1
Search

RING1

0.50	Ring finger protein 1

0.66	GO:0035518	histone H2A monoubiquitination
0.60	GO:0048593	camera-type eye morphogenesis
0.58	GO:0009952	anterior/posterior pattern specification
0.56	GO:0045892	negative regulation of transcription, DNA-templated
0.51	GO:0050790	regulation of catalytic activity
0.39	GO:0006351	transcription, DNA-templated
0.37	GO:0070317	negative regulation of G0 to G1 transition

0.59	GO:0097027	ubiquitin-protein transferase activator activity
0.56	GO:0003682	chromatin binding
0.50	GO:0016874	ligase activity
0.38	GO:0046872	metal ion binding
0.37	GO:0016740	transferase activity
0.36	GO:0005515	protein binding

0.85	GO:0035102	PRC1 complex
0.64	GO:0001739	sex chromatin
0.58	GO:0016604	nuclear body
0.54	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.50

GO:0016874

sp|Q06609|RAD51_HUMAN
DNA repair protein RAD51 homolog 1
Search

RAD51

0.74	DNA repair protein RAD51 homolog A

0.84	GO:1990426	mitotic recombination-dependent replication fork processing
0.75	GO:0000724	double-strand break repair via homologous recombination
0.56	GO:0090735	DNA repair complex assembly
0.55	GO:0072757	cellular response to camptothecin
0.54	GO:0051106	positive regulation of DNA ligation
0.54	GO:0072711	cellular response to hydroxyurea
0.53	GO:0010212	response to ionizing radiation
0.53	GO:0006312	mitotic recombination
0.53	GO:0010569	regulation of double-strand break repair via homologous recombination
0.53	GO:0070192	chromosome organization involved in meiotic cell cycle

0.72	GO:0000150	recombinase activity
0.71	GO:0003697	single-stranded DNA binding
0.70	GO:0003690	double-stranded DNA binding
0.69	GO:0008094	DNA-dependent ATPase activity
0.54	GO:0030554	adenyl nucleotide binding
0.53	GO:0032555	purine ribonucleotide binding
0.53	GO:0008144	drug binding
0.53	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0070182	DNA polymerase binding
0.50	GO:0008022	protein C-terminus binding

0.60	GO:0005634	nucleus
0.50	GO:0035861	site of double-strand break
0.50	GO:0000793	condensed chromosome
0.49	GO:0048471	perinuclear region of cytoplasm
0.49	GO:0000781	chromosome, telomeric region
0.47	GO:0031974	membrane-enclosed lumen
0.46	GO:0000785	chromatin
0.45	GO:0005829	cytosol
0.42	GO:0005739	mitochondrion
0.41	GO:0043234	protein complex

sp|Q06643|TNFC_HUMAN
Lymphotoxin-beta
Search

LTB

0.97	Lymphotoxin-beta

0.75	GO:0010469	regulation of receptor activity
0.74	GO:0006955	immune response
0.72	GO:0045084	positive regulation of interleukin-12 biosynthetic process
0.69	GO:0048535	lymph node development
0.65	GO:0043588	skin development
0.46	GO:0010467	gene expression
0.39	GO:0033209	tumor necrosis factor-mediated signaling pathway
0.38	GO:0007267	cell-cell signaling

0.84	GO:0005164	tumor necrosis factor receptor binding
0.80	GO:0005125	cytokine activity

0.72	GO:0005615	extracellular space
0.35	GO:0005886	plasma membrane
0.30	GO:0016021	integral component of membrane

sp|Q06710|PAX8_HUMAN
Paired box protein Pax-8
Search

PAX8

0.82	Paired box protein Pax-8

0.69	GO:0007275	multicellular organism development
0.61	GO:2000611	positive regulation of thyroid hormone generation
0.60	GO:2000612	regulation of thyroid-stimulating hormone secretion
0.58	GO:0097659	nucleic acid-templated transcription
0.57	GO:1900218	negative regulation of apoptotic process involved in metanephric nephron tubule development
0.57	GO:0071371	cellular response to gonadotropin stimulus
0.57	GO:2001141	regulation of RNA biosynthetic process
0.57	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.57	GO:0060231	mesenchymal to epithelial transition
0.56	GO:1900211	regulation of mesenchymal cell apoptotic process involved in metanephros development

0.56	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding
0.45	GO:0003700	DNA binding transcription factor activity
0.40	GO:0000978	RNA polymerase II proximal promoter sequence-specific DNA binding
0.37	GO:0004996	thyroid-stimulating hormone receptor activity
0.36	GO:0035326	enhancer binding
0.36	GO:0005515	protein binding

0.61	GO:0005634	nucleus
0.48	GO:0070013	intracellular organelle lumen
0.43	GO:0044446	intracellular organelle part
0.35	GO:0005667	transcription factor complex

sp|Q06730|ZN33A_HUMAN
Zinc finger protein 33A
Search

0.75	RB associated KRAB zinc finger

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.38	GO:1902679	negative regulation of RNA biosynthetic process
0.37	GO:0006351	transcription, DNA-templated
0.36	GO:1902680	positive regulation of RNA biosynthetic process

0.52	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.43	GO:0003700	DNA binding transcription factor activity
0.35	GO:0005515	protein binding

0.44	GO:0005622	intracellular
0.40	GO:0043227	membrane-bounded organelle
0.35	GO:0031974	membrane-enclosed lumen
0.34	GO:0043228	non-membrane-bounded organelle
0.34	GO:0044422	organelle part

sp|Q06732|ZN33B_HUMAN
Zinc finger protein 33B
Search

0.73	RB associated KRAB zinc finger

0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.40	GO:1902679	negative regulation of RNA biosynthetic process
0.38	GO:0006351	transcription, DNA-templated
0.36	GO:1902680	positive regulation of RNA biosynthetic process

0.52	GO:0046872	metal ion binding
0.51	GO:0003676	nucleic acid binding
0.40	GO:0003700	DNA binding transcription factor activity
0.36	GO:0005515	protein binding

0.44	GO:0005622	intracellular
0.41	GO:0043227	membrane-bounded organelle
0.37	GO:0031974	membrane-enclosed lumen
0.36	GO:0043228	non-membrane-bounded organelle
0.35	GO:0044422	organelle part

sp|Q06787|FMR1_HUMAN
Synaptic functional regulator FMR1
Search

FMR1

0.96	Fragile X mental retardation 1

0.64	GO:1901254	positive regulation of intracellular transport of viral material
0.63	GO:0044830	modulation by host of viral RNA genome replication
0.62	GO:0098908	regulation of neuronal action potential
0.62	GO:0033129	positive regulation of histone phosphorylation
0.61	GO:1902416	positive regulation of mRNA binding
0.60	GO:2000637	positive regulation of gene silencing by miRNA
0.60	GO:0002092	positive regulation of receptor internalization
0.59	GO:0060998	regulation of dendritic spine development
0.59	GO:1902373	negative regulation of mRNA catabolic process
0.59	GO:0051489	regulation of filopodium assembly

0.61	GO:0034046	poly(G) binding
0.61	GO:1990825	sequence-specific mRNA binding
0.60	GO:0035613	RNA stem-loop binding
0.60	GO:0035197	siRNA binding
0.59	GO:0035198	miRNA binding
0.59	GO:0002151	G-quadruplex RNA binding
0.59	GO:0030371	translation repressor activity
0.59	GO:0008266	poly(U) RNA binding
0.58	GO:0033592	RNA strand annealing activity
0.58	GO:0044325	ion channel binding

0.63	GO:0019034	viral replication complex
0.61	GO:1990124	messenger ribonucleoprotein complex
0.59	GO:0032797	SMN complex
0.58	GO:0043204	perikaryon
0.58	GO:0030426	growth cone
0.57	GO:0005844	polysome
0.55	GO:0048471	perinuclear region of cytoplasm
0.55	GO:0036464	cytoplasmic ribonucleoprotein granule
0.52	GO:0005730	nucleolus
0.50	GO:0005654	nucleoplasm

sp|Q06828|FMOD_HUMAN
Fibromodulin
Search

FMOD

0.97	Fibromodulin

0.65	GO:0030199	collagen fibril organization
0.48	GO:0007409	axonogenesis
0.47	GO:0007601	visual perception
0.41	GO:0032914	positive regulation of transforming growth factor beta1 production
0.40	GO:0048513	animal organ development
0.38	GO:0048598	embryonic morphogenesis
0.38	GO:0045944	positive regulation of transcription by RNA polymerase II
0.37	GO:0042340	keratan sulfate catabolic process
0.37	GO:0007181	transforming growth factor beta receptor complex assembly
0.36	GO:0018146	keratan sulfate biosynthetic process

0.41	GO:0005518	collagen binding
0.32	GO:0004930	G-protein coupled receptor activity

0.75	GO:0005578	proteinaceous extracellular matrix
0.56	GO:0005615	extracellular space
0.39	GO:0044420	extracellular matrix component
0.39	GO:0005581	collagen trimer
0.37	GO:0099512	supramolecular fiber
0.36	GO:0043202	lysosomal lumen
0.36	GO:0005796	Golgi lumen
0.33	GO:1903561	extracellular vesicle
0.30	GO:0031224	intrinsic component of membrane

sp|Q06830|PRDX1_HUMAN
Peroxiredoxin-1
Search

PRDX1

0.84	Boundary element associated factor

0.69	GO:0098869	cellular oxidant detoxification
0.68	GO:0045454	cell redox homeostasis
0.53	GO:0055114	oxidation-reduction process
0.52	GO:0030101	natural killer cell activation
0.52	GO:0042267	natural killer cell mediated cytotoxicity
0.51	GO:0042345	regulation of NF-kappaB import into nucleus
0.50	GO:0034101	erythrocyte homeostasis
0.49	GO:0032872	regulation of stress-activated MAPK cascade
0.48	GO:0042744	hydrogen peroxide catabolic process
0.48	GO:0008283	cell proliferation

0.73	GO:0051920	peroxiredoxin activity
0.50	GO:0045296	cadherin binding
0.47	GO:0004601	peroxidase activity
0.46	GO:0042802	identical protein binding
0.40	GO:0003677	DNA binding
0.33	GO:0003723	RNA binding
0.33	GO:0046983	protein dimerization activity
0.33	GO:0020037	heme binding

0.49	GO:0043209	myelin sheath
0.43	GO:0005634	nucleus
0.41	GO:0005739	mitochondrion
0.36	GO:0031012	extracellular matrix
0.36	GO:0070062	extracellular exosome
0.35	GO:0005829	cytosol
0.35	GO:0042470	melanosome
0.35	GO:0031907	microbody lumen
0.35	GO:0000791	euchromatin
0.34	GO:0044439	peroxisomal part

0.73	EC:1.11.1.15	GO:0051920
0.47	KEGG:R03532	GO:0004601

sp|Q06889|EGR3_HUMAN
Early growth response protein 3
Search

EGR3

0.82	Early growth response protein 3

0.57	GO:0006351	transcription, DNA-templated
0.57	GO:0002042	cell migration involved in sprouting angiogenesis
0.56	GO:0035767	endothelial cell chemotaxis
0.56	GO:1903506	regulation of nucleic acid-templated transcription
0.56	GO:2000112	regulation of cellular macromolecule biosynthetic process
0.55	GO:0010468	regulation of gene expression
0.55	GO:0001938	positive regulation of endothelial cell proliferation
0.55	GO:0035924	cellular response to vascular endothelial growth factor stimulus
0.54	GO:0044344	cellular response to fibroblast growth factor stimulus
0.51	GO:0043066	negative regulation of apoptotic process

0.54	GO:0003677	DNA binding
0.53	GO:0046872	metal ion binding
0.35	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding

0.60

GO:0005634

nucleus

sp|Q06945|SOX4_HUMAN
Transcription factor SOX-4
Search

SOX4

0.88

SRY-box 4

0.87	GO:2000761	positive regulation of N-terminal peptidyl-lysine acetylation
0.86	GO:0035910	ascending aorta morphogenesis
0.86	GO:0002328	pro-B cell differentiation
0.86	GO:0003289	atrial septum primum morphogenesis
0.86	GO:0003357	noradrenergic neuron differentiation
0.85	GO:0014009	glial cell proliferation
0.85	GO:0046826	negative regulation of protein export from nucleus
0.85	GO:0042769	DNA damage response, detection of DNA damage
0.85	GO:0003183	mitral valve morphogenesis
0.85	GO:0003211	cardiac ventricle formation

0.83	GO:0001105	RNA polymerase II transcription coactivator activity
0.80	GO:0001046	core promoter sequence-specific DNA binding
0.79	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.71	GO:0046982	protein heterodimerization activity

0.73	GO:0044798	nuclear transcription factor complex
0.67	GO:0005654	nucleoplasm
0.59	GO:0005739	mitochondrion

sp|Q07001|ACHD_HUMAN
Acetylcholine receptor subunit delta
Search

CHRND

0.89	Acetylcholine receptor subunit delta

0.77	GO:0060079	excitatory postsynaptic potential
0.60	GO:0034220	ion transmembrane transport
0.49	GO:0048630	skeletal muscle tissue growth
0.49	GO:0035094	response to nicotine
0.49	GO:0007271	synaptic transmission, cholinergic
0.48	GO:0007274	neuromuscular synaptic transmission
0.48	GO:0050881	musculoskeletal movement
0.43	GO:0006941	striated muscle contraction
0.39	GO:0006812	cation transport
0.37	GO:0050905	neuromuscular process

0.80	GO:0022848	acetylcholine-gated cation-selective channel activity
0.69	GO:0099600	transmembrane receptor activity
0.52	GO:0042166	acetylcholine binding
0.36	GO:0004252	serine-type endopeptidase activity
0.35	GO:0005515	protein binding

0.77	GO:0045211	postsynaptic membrane
0.72	GO:0030054	cell junction
0.51	GO:0005892	acetylcholine-gated channel complex
0.42	GO:0005654	nucleoplasm
0.42	GO:0005829	cytosol

0.36

GO:0004252

sp|Q07002|CDK18_HUMAN
Cyclin-dependent kinase 18
Search

CDK18

0.97	PCTAIRE-motif protein kinase 3

0.63	GO:0006468	protein phosphorylation
0.36	GO:0051726	regulation of cell cycle
0.35	GO:0006368	transcription elongation from RNA polymerase II promoter
0.35	GO:0051301	cell division
0.34	GO:0045944	positive regulation of transcription by RNA polymerase II

0.67	GO:0004674	protein serine/threonine kinase activity
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.48	GO:0097472	cyclin-dependent protein kinase activity
0.35	GO:0030332	cyclin binding
0.34	GO:0044212	transcription regulatory region DNA binding
0.34	GO:0008134	transcription factor binding

0.40	GO:0005634	nucleus
0.36	GO:0005737	cytoplasm
0.35	GO:0000307	cyclin-dependent protein kinase holoenzyme complex
0.34	GO:0005694	chromosome
0.34	GO:0031974	membrane-enclosed lumen
0.33	GO:0044446	intracellular organelle part
0.30	GO:0016020	membrane

0.67

GO:0004674

sp|Q07011|TNR9_HUMAN
Tumor necrosis factor receptor superfamily member 9
Search

TNFRSF9

0.97	Tumor necrosis factor receptor superfamily member 9

0.76	GO:0008285	negative regulation of cell proliferation
0.75	GO:0006915	apoptotic process
0.75	GO:2001183	negative regulation of interleukin-12 secretion
0.75	GO:2001180	negative regulation of interleukin-10 secretion
0.71	GO:0070207	protein homotrimerization
0.57	GO:0033209	tumor necrosis factor-mediated signaling pathway
0.55	GO:0032496	response to lipopolysaccharide
0.53	GO:0006954	inflammatory response
0.51	GO:0006955	immune response
0.51	GO:0042981	regulation of apoptotic process

0.68	GO:0019955	cytokine binding
0.63	GO:0004872	receptor activity
0.46	GO:0004871	signal transducer activity
0.32	GO:0046872	metal ion binding

0.80	GO:0009897	external side of plasma membrane
0.60	GO:0005615	extracellular space
0.47	GO:0005887	integral component of plasma membrane
0.36	GO:0005829	cytosol

sp|Q07020|RL18_HUMAN
60S ribosomal protein L18
Search

RPL18

0.74	Ribosomal protein L18

0.60	GO:0043043	peptide biosynthetic process
0.56	GO:0044267	cellular protein metabolic process
0.54	GO:0010467	gene expression
0.53	GO:0009059	macromolecule biosynthetic process
0.35	GO:0097421	liver regeneration
0.35	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
0.34	GO:0006614	SRP-dependent cotranslational protein targeting to membrane
0.34	GO:0019083	viral transcription
0.33	GO:0016072	rRNA metabolic process
0.33	GO:0042254	ribosome biogenesis

0.64	GO:0003735	structural constituent of ribosome
0.40	GO:0003723	RNA binding

0.61	GO:0005840	ribosome
0.48	GO:0005844	polysome
0.47	GO:0044445	cytosolic part
0.44	GO:0005730	nucleolus
0.43	GO:0005783	endoplasmic reticulum
0.36	GO:0005925	focal adhesion
0.30	GO:0031224	intrinsic component of membrane

sp|Q07021|C1QBP_HUMAN
Complement component 1 Q subcomponent-binding protein, mitochondrial
Search

C1QBP

0.86	LOW QUALITY PROTEIN: complement component 1 Q subcomponent-binding protein, mitochondrial

0.61	GO:0039534	negative regulation of MDA-5 signaling pathway
0.61	GO:1901165	positive regulation of trophoblast cell migration
0.60	GO:2000510	positive regulation of dendritic cell chemotaxis
0.60	GO:0039536	negative regulation of RIG-I signaling pathway
0.60	GO:0032695	negative regulation of interleukin-12 production
0.59	GO:0048025	negative regulation of mRNA splicing, via spliceosome
0.59	GO:0090023	positive regulation of neutrophil chemotaxis
0.59	GO:0032689	negative regulation of interferon-gamma production
0.59	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading
0.58	GO:0030449	regulation of complement activation

0.62	GO:0030984	kininogen binding
0.61	GO:0001849	complement component C1q binding
0.57	GO:0005540	hyaluronic acid binding
0.55	GO:0003714	transcription corepressor activity
0.51	GO:0008134	transcription factor binding
0.44	GO:0031690	adrenergic receptor binding
0.44	GO:0097177	mitochondrial ribosome binding
0.40	GO:0003729	mRNA binding
0.40	GO:0005080	protein kinase C binding
0.37	GO:0004386	helicase activity

0.75	GO:0005759	mitochondrial matrix
0.52	GO:0009986	cell surface
0.49	GO:0005829	cytosol
0.46	GO:0005634	nucleus
0.43	GO:0005886	plasma membrane
0.39	GO:0005576	extracellular region
0.36	GO:0043232	intracellular non-membrane-bounded organelle
0.33	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.32

GO:0003887

sp|Q07065|CKAP4_HUMAN
Cytoskeleton-associated protein 4
Search

CKAP4

0.97	Cytoskeleton-associated protein 4

0.40	GO:0043312	neutrophil degranulation
0.39	GO:0043687	post-translational protein modification
0.33	GO:0006357	regulation of transcription by RNA polymerase II
0.32	GO:0030866	cortical actin cytoskeleton organization
0.32	GO:0016575	histone deacetylation
0.32	GO:0006468	protein phosphorylation
0.32	GO:0007015	actin filament organization
0.32	GO:0045893	positive regulation of transcription, DNA-templated
0.32	GO:0006897	endocytosis
0.32	GO:0009306	protein secretion

0.36	GO:0003723	RNA binding
0.32	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding
0.32	GO:0004674	protein serine/threonine kinase activity
0.32	GO:0008157	protein phosphatase 1 binding
0.32	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
0.32	GO:0008270	zinc ion binding
0.32	GO:0046983	protein dimerization activity
0.32	GO:0005524	ATP binding

0.66	GO:0005811	lipid droplet
0.66	GO:0005791	rough endoplasmic reticulum
0.65	GO:0016607	nuclear speck
0.64	GO:0036464	cytoplasmic ribonucleoprotein granule
0.57	GO:0005829	cytosol
0.41	GO:0031012	extracellular matrix
0.41	GO:0048471	perinuclear region of cytoplasm
0.40	GO:0035579	specific granule membrane
0.40	GO:0035577	azurophil granule membrane
0.40	GO:0042599	lamellar body

0.32

GO:0004674

sp|Q07075|AMPE_HUMAN
Glutamyl aminopeptidase
Search

ENPEP

0.54	Glutamyl aminopeptidase

0.86	GO:0002003	angiotensin maturation
0.56	GO:0032835	glomerulus development
0.56	GO:0008283	cell proliferation
0.55	GO:0016477	cell migration
0.54	GO:0001525	angiogenesis
0.45	GO:0043171	peptide catabolic process
0.36	GO:0044266	multicellular organismal macromolecule catabolic process
0.36	GO:0044256	protein digestion
0.36	GO:0044268	multicellular organismal protein metabolic process
0.36	GO:0044243	multicellular organismal catabolic process

0.76	GO:0070006	metalloaminopeptidase activity
0.63	GO:0008270	zinc ion binding
0.46	GO:0042277	peptide binding

0.55	GO:0005903	brush border
0.54	GO:0009897	external side of plasma membrane
0.54	GO:0016324	apical plasma membrane
0.50	GO:0031410	cytoplasmic vesicle
0.48	GO:0005765	lysosomal membrane
0.37	GO:0070062	extracellular exosome
0.35	GO:0031983	vesicle lumen
0.34	GO:0012506	vesicle membrane
0.34	GO:0005887	integral component of plasma membrane
0.32	GO:0005789	endoplasmic reticulum membrane

sp|Q07092|COGA1_HUMAN
Collagen alpha-1(XVI) chain
Search

COL16A1

0.85	Collagen type XVI alpha 1 chain

0.68	GO:0033622	integrin activation
0.67	GO:0051894	positive regulation of focal adhesion assembly
0.66	GO:0033627	cell adhesion mediated by integrin
0.66	GO:0071230	cellular response to amino acid stimulus
0.39	GO:0030198	extracellular matrix organization
0.37	GO:0032501	multicellular organismal process
0.37	GO:0009653	anatomical structure morphogenesis
0.36	GO:0010951	negative regulation of endopeptidase activity
0.36	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway
0.36	GO:0009888	tissue development

0.64	GO:0005178	integrin binding
0.41	GO:0005201	extracellular matrix structural constituent
0.37	GO:0004867	serine-type endopeptidase inhibitor activity
0.37	GO:0048407	platelet-derived growth factor binding
0.36	GO:0005509	calcium ion binding
0.35	GO:0046332	SMAD binding
0.34	GO:0042802	identical protein binding
0.32	GO:0042302	structural constituent of cuticle

0.68	GO:0005581	collagen trimer
0.59	GO:0031012	extracellular matrix
0.36	GO:0005615	extracellular space
0.36	GO:0099081	supramolecular polymer
0.36	GO:0005788	endoplasmic reticulum lumen
0.30	GO:0031224	intrinsic component of membrane

sp|Q07108|CD69_HUMAN
Early activation antigen CD69
Search

CD69

0.97	Type II membrane protein CD69 splice variant

0.69	GO:0035690	cellular response to drug
0.41	GO:0001867	complement activation, lectin pathway
0.36	GO:0007165	signal transduction

0.69	GO:0030246	carbohydrate binding
0.66	GO:0042803	protein homodimerization activity
0.43	GO:0005509	calcium ion binding
0.37	GO:0099600	transmembrane receptor activity
0.37	GO:0038023	signaling receptor activity

0.70	GO:0009897	external side of plasma membrane
0.53	GO:0043234	protein complex
0.37	GO:0005887	integral component of plasma membrane

sp|Q07157|ZO1_HUMAN
Tight junction protein ZO-1
Search

TJP1

0.91	Tight junction protein ZO-1

0.52	GO:0001825	blastocyst formation
0.52	GO:0007605	sensory perception of sound
0.40	GO:0090557	establishment of endothelial intestinal barrier
0.39	GO:0071000	response to magnetism
0.38	GO:0043116	negative regulation of vascular permeability
0.38	GO:0007043	cell-cell junction assembly
0.38	GO:0071333	cellular response to glucose stimulus
0.38	GO:1901350	cell-cell signaling involved in cell-cell junction organization
0.38	GO:0045471	response to ethanol
0.37	GO:0032496	response to lipopolysaccharide

0.56	GO:0071253	connexin binding
0.50	GO:0019904	protein domain specific binding
0.39	GO:0045296	cadherin binding
0.39	GO:0005516	calmodulin binding
0.37	GO:0008022	protein C-terminus binding
0.33	GO:0016301	kinase activity
0.33	GO:0032559	adenyl ribonucleotide binding
0.33	GO:0008144	drug binding
0.33	GO:0035639	purine ribonucleoside triphosphate binding

0.81	GO:0005923	bicellular tight junction
0.56	GO:0046581	intercellular canaliculus
0.55	GO:0016327	apicolateral plasma membrane
0.54	GO:0014704	intercalated disc
0.54	GO:0005913	cell-cell adherens junction
0.52	GO:0045177	apical part of cell
0.45	GO:0005829	cytosol
0.44	GO:0005634	nucleus
0.43	GO:0043234	protein complex
0.40	GO:0005921	gap junction

sp|Q07283|TRHY_HUMAN
Trichohyalin
Search

TCHH

0.65	Trichohyalin

0.56	GO:0031424	keratinization
0.47	GO:0012501	programmed cell death
0.47	GO:0045109	intermediate filament organization
0.36	GO:0006402	mRNA catabolic process
0.36	GO:0090501	RNA phosphodiester bond hydrolysis
0.36	GO:0006364	rRNA processing
0.35	GO:0008033	tRNA processing
0.34	GO:0007018	microtubule-based movement
0.32	GO:0016024	CDP-diacylglycerol biosynthetic process

0.69	GO:0005509	calcium ion binding
0.57	GO:0046914	transition metal ion binding
0.44	GO:0030674	protein binding, bridging
0.38	GO:0008995	ribonuclease E activity
0.36	GO:0004521	endoribonuclease activity
0.35	GO:0000287	magnesium ion binding
0.35	GO:0003777	microtubule motor activity
0.35	GO:0003723	RNA binding
0.34	GO:0051015	actin filament binding
0.34	GO:0008017	microtubule binding

0.51	GO:0001533	cornified envelope
0.45	GO:0005856	cytoskeleton
0.44	GO:0005829	cytosol
0.36	GO:0009898	cytoplasmic side of plasma membrane
0.35	GO:0044446	intracellular organelle part
0.33	GO:0043234	protein complex
0.30	GO:0016021	integral component of membrane

0.33

EC:2.7.7.41

GO:0004605

sp|Q07325|CXCL9_HUMAN
C-X-C motif chemokine 9
Search

CXCL9

0.45	C-X-C motif chemokine

0.82	GO:0060326	cell chemotaxis
0.79	GO:0006954	inflammatory response
0.74	GO:0006955	immune response
0.72	GO:0043950	positive regulation of cAMP-mediated signaling
0.71	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol
0.71	GO:0010469	regulation of receptor activity
0.70	GO:0030816	positive regulation of cAMP metabolic process
0.70	GO:1901741	positive regulation of myoblast fusion
0.69	GO:0045663	positive regulation of myoblast differentiation
0.63	GO:0042127	regulation of cell proliferation

0.84	GO:0008009	chemokine activity
0.75	GO:0048248	CXCR3 chemokine receptor binding
0.36	GO:0005153	interleukin-8 receptor binding
0.35	GO:0004721	phosphoprotein phosphatase activity
0.35	GO:0005509	calcium ion binding

0.70	GO:0005615	extracellular space
0.64	GO:0009897	external side of plasma membrane
0.32	GO:0005622	intracellular

0.35

GO:0004721

sp|Q07326|PIGF_HUMAN
Phosphatidylinositol-glycan biosynthesis class F protein
Search

PIGF

0.97	Phosphatidylinositol glycan anchor biosynthesis class F

0.78	GO:0006506	GPI anchor biosynthetic process
0.32	GO:0016310	phosphorylation
0.32	GO:0032259	methylation
0.31	GO:0055085	transmembrane transport

0.38	GO:0004307	ethanolaminephosphotransferase activity
0.32	GO:0016301	kinase activity
0.32	GO:0008168	methyltransferase activity
0.32	GO:0003723	RNA binding
0.31	GO:0022857	transmembrane transporter activity

0.72	GO:0005789	endoplasmic reticulum membrane
0.30	GO:0031224	intrinsic component of membrane

0.38

EC:2.7.8.1

GO:0004307

sp|Q07343|PDE4B_HUMAN
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
Search

PDE4B

0.56	Phosphodiesterase

0.60	GO:0007165	signal transduction
0.57	GO:0032743	positive regulation of interleukin-2 production
0.56	GO:0032729	positive regulation of interferon-gamma production
0.56	GO:0001780	neutrophil homeostasis
0.55	GO:0006198	cAMP catabolic process
0.54	GO:0030593	neutrophil chemotaxis
0.53	GO:0002253	activation of immune response
0.53	GO:0071222	cellular response to lipopolysaccharide
0.52	GO:0035690	cellular response to drug
0.43	GO:0006939	smooth muscle contraction

0.79	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
0.55	GO:0030552	cAMP binding
0.54	GO:0046872	metal ion binding
0.52	GO:0043015	gamma-tubulin binding
0.38	GO:0044325	ion channel binding

0.55	GO:0060076	excitatory synapse
0.54	GO:0043197	dendritic spine
0.53	GO:0014069	postsynaptic density
0.53	GO:0000930	gamma-tubulin complex
0.52	GO:0008021	synaptic vesicle
0.50	GO:0005813	centrosome
0.46	GO:0005829	cytosol
0.41	GO:0071944	cell periphery
0.38	GO:0030018	Z disc
0.38	GO:0034704	calcium channel complex

0.79

EC:3.1.4.17

GO:0004114

sp|Q07352|TISB_HUMAN
mRNA decay activator protein ZFP36L1
Search

ZFP36L1

0.96	ZFP36 ring finger protein like 1

0.79	GO:1904582	positive regulation of intracellular mRNA localization
0.78	GO:0097403	cellular response to raffinose
0.78	GO:0061158	3'-UTR-mediated mRNA destabilization
0.78	GO:1902172	regulation of keratinocyte apoptotic process
0.77	GO:0045657	positive regulation of monocyte differentiation
0.76	GO:0045647	negative regulation of erythrocyte differentiation
0.76	GO:1904628	cellular response to phorbol 13-acetate 12-myristate
0.76	GO:0003343	septum transversum development
0.75	GO:0070371	ERK1 and ERK2 cascade
0.74	GO:0038066	p38MAPK cascade

0.76	GO:0035925	mRNA 3'-UTR AU-rich region binding
0.75	GO:0071889	14-3-3 protein binding
0.54	GO:0046872	metal ion binding

0.69	GO:0000932	P-body
0.54	GO:0005634	nucleus
0.47	GO:0005829	cytosol

sp|Q07444|NKG2E_HUMAN
NKG2-E type II integral membrane protein
Search

0.96	NK cell receptor C

0.39	GO:0006968	cellular defense response
0.36	GO:0002228	natural killer cell mediated immunity
0.35	GO:0007165	signal transduction
0.34	GO:0050776	regulation of immune response

0.67	GO:0030246	carbohydrate binding
0.46	GO:0023024	MHC class I protein complex binding
0.38	GO:1990405	protein antigen binding
0.36	GO:0099600	transmembrane receptor activity
0.36	GO:0038023	signaling receptor activity

0.42	GO:0043235	receptor complex
0.35	GO:0005887	integral component of plasma membrane

sp|Q07507|DERM_HUMAN
Dermatopontin
Search

DPT

0.97	Dermatopontin

0.84	GO:0030199	collagen fibril organization
0.75	GO:0008285	negative regulation of cell proliferation
0.44	GO:0007155	cell adhesion

0.74	GO:0031012	extracellular matrix
0.73	GO:0005615	extracellular space
0.43	GO:1903561	extracellular vesicle

sp|Q075Z2|BSPH1_HUMAN
Binder of sperm protein homolog 1
Search

BSPH1

0.97	Binder of sperm protein homolog 1

0.86	GO:0048240	sperm capacitation
0.61	GO:0007338	single fertilization

0.83

GO:0008201

heparin binding

0.76	GO:0009986	cell surface
0.51	GO:0005576	extracellular region

sp|Q07617|SPAG1_HUMAN
Sperm-associated antigen 1
Search

SPAG1

0.93	Sperm-associated antigen 1

0.53	GO:0070286	axonemal dynein complex assembly
0.51	GO:0007338	single fertilization

0.44	GO:0032550	purine ribonucleoside binding
0.44	GO:0019001	guanyl nucleotide binding
0.39	GO:0032553	ribonucleotide binding
0.39	GO:0035639	purine ribonucleoside triphosphate binding
0.38	GO:0016787	hydrolase activity

0.68

GO:0005829

cytosol

0.38

GO:0016787

sp|Q07627|KRA11_HUMAN
Keratin-associated protein 1-1
Search

0.97	Keratin intermediate-filament type I protein variant 2

0.41	GO:0031424	keratinization
0.33	GO:0042633	hair cycle
0.33	GO:0007568	aging

0.36	GO:0030280	structural constituent of epidermis
0.35	GO:0042802	identical protein binding
0.34	GO:0039660	structural constituent of virion

0.83	GO:0045095	keratin filament
0.37	GO:0005829	cytosol

sp|Q07654|TFF3_HUMAN
Trefoil factor 3
Search

TFF3

0.95	Trefoil factor 3

0.71	GO:0010906	regulation of glucose metabolic process
0.70	GO:0007586	digestion
0.63	GO:0042060	wound healing
0.50	GO:0010669	epithelial structure maintenance
0.45	GO:0003008	system process
0.40	GO:0060455	negative regulation of gastric acid secretion
0.39	GO:0043031	negative regulation of macrophage activation
0.39	GO:0010033	response to organic substance
0.39	GO:0009966	regulation of signal transduction
0.39	GO:0050728	negative regulation of inflammatory response

0.41	GO:0005515	protein binding
0.39	GO:0030545	receptor regulator activity
0.35	GO:0005198	structural molecule activity
0.34	GO:0004521	endoribonuclease activity

0.69	GO:0030141	secretory granule
0.60	GO:0005615	extracellular space
0.49	GO:0005578	proteinaceous extracellular matrix
0.44	GO:1903561	extracellular vesicle
0.36	GO:0005882	intermediate filament

sp|Q07666|KHDR1_HUMAN
KH domain-containing, RNA-binding, signal transduction-associated protein 1
Search

KHDRBS1

0.94	KH RNA binding domain containing, signal transduction associated 1

0.59	GO:0046833	positive regulation of RNA export from nucleus
0.58	GO:0048024	regulation of mRNA splicing, via spliceosome
0.55	GO:0045948	positive regulation of translational initiation
0.51	GO:0009967	positive regulation of signal transduction
0.49	GO:0051259	protein oligomerization
0.49	GO:0007166	cell surface receptor signaling pathway
0.49	GO:0045892	negative regulation of transcription, DNA-templated
0.38	GO:0000086	G2/M transition of mitotic cell cycle
0.37	GO:0006397	mRNA processing
0.35	GO:0007050	cell cycle arrest

0.59	GO:0008266	poly(U) RNA binding
0.59	GO:0008143	poly(A) binding
0.56	GO:0005070	SH3/SH2 adaptor activity
0.54	GO:0019904	protein domain specific binding
0.53	GO:0042802	identical protein binding
0.42	GO:0046982	protein heterodimerization activity
0.35	GO:0032403	protein complex binding
0.33	GO:0003677	DNA binding

0.48	GO:0005654	nucleoplasm
0.37	GO:0070618	Grb2-Sos complex
0.34	GO:0005829	cytosol
0.30	GO:0016021	integral component of membrane

sp|Q07687|DLX2_HUMAN
Homeobox protein DLX-2
Search

DLX2

0.92	Homeobox protein DLX-2

0.65	GO:0021893	cerebral cortex GABAergic interneuron fate commitment
0.65	GO:1902871	positive regulation of amacrine cell differentiation
0.64	GO:0021882	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment
0.64	GO:0048755	branching morphogenesis of a nerve
0.63	GO:0048715	negative regulation of oligodendrocyte differentiation
0.63	GO:0046533	negative regulation of photoreceptor cell differentiation
0.62	GO:0021544	subpallium development
0.61	GO:0021772	olfactory bulb development
0.61	GO:0009954	proximal/distal pattern formation
0.61	GO:0045746	negative regulation of Notch signaling pathway

0.64	GO:0043565	sequence-specific DNA binding
0.57	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding
0.57	GO:0003727	single-stranded RNA binding
0.56	GO:0001012	RNA polymerase II regulatory region DNA binding
0.55	GO:0003682	chromatin binding
0.53	GO:0003690	double-stranded DNA binding
0.36	GO:0005515	protein binding

0.61

GO:0005634

nucleus

sp|Q07699|SCN1B_HUMAN
Sodium channel subunit beta-1
Search

SCN1B

0.96	Voltage-gated sodium channel beta 1 subunit splice variant B

0.72	GO:0006814	sodium ion transport
0.66	GO:0065009	regulation of molecular function
0.62	GO:0086012	membrane depolarization during cardiac muscle cell action potential
0.62	GO:0060371	regulation of atrial cardiac muscle cell membrane depolarization
0.61	GO:0086019	cell-cell signaling involved in cardiac conduction
0.60	GO:0086002	cardiac muscle cell action potential involved in contraction
0.60	GO:0010765	positive regulation of sodium ion transport
0.59	GO:0086091	regulation of heart rate by cardiac conduction
0.59	GO:1902305	regulation of sodium ion transmembrane transport
0.57	GO:0021966	corticospinal neuron axon guidance

0.85	GO:0017080	sodium channel regulator activity
0.63	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential
0.52	GO:0008200	ion channel inhibitor activity
0.48	GO:0044325	ion channel binding
0.43	GO:0022832	voltage-gated channel activity
0.42	GO:0022839	ion gated channel activity
0.42	GO:0008381	mechanosensitive ion channel activity
0.38	GO:0070008	serine-type exopeptidase activity
0.37	GO:0004252	serine-type endopeptidase activity
0.33	GO:0016758	transferase activity, transferring hexosyl groups

0.83	GO:0001518	voltage-gated sodium channel complex
0.55	GO:0033268	node of Ranvier
0.54	GO:0030315	T-tubule
0.53	GO:0014704	intercalated disc
0.48	GO:0030018	Z disc
0.36	GO:0043209	myelin sheath
0.36	GO:0043025	neuronal cell body
0.34	GO:0005576	extracellular region

0.38

GO:0070008

sp|Q07812|BAX_HUMAN
Apoptosis regulator BAX
Search

BAX

0.96	Apoptosis regulator BAX

0.78	GO:0043065	positive regulation of apoptotic process
0.63	GO:0032976	release of matrix enzymes from mitochondria
0.63	GO:0001836	release of cytochrome c from mitochondria
0.62	GO:0001783	B cell apoptotic process
0.61	GO:0043653	mitochondrial fragmentation involved in apoptotic process
0.61	GO:1900103	positive regulation of endoplasmic reticulum unfolded protein response
0.60	GO:0008053	mitochondrial fusion
0.60	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
0.60	GO:0043496	regulation of protein homodimerization activity
0.60	GO:0032461	positive regulation of protein oligomerization

0.62	GO:0051434	BH3 domain binding
0.56	GO:0030544	Hsp70 protein binding
0.54	GO:0042803	protein homodimerization activity
0.52	GO:0046982	protein heterodimerization activity
0.51	GO:0008289	lipid binding
0.51	GO:0022803	passive transmembrane transporter activity
0.51	GO:0051087	chaperone binding
0.36	GO:0047115	trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity
0.35	GO:0008199	ferric iron binding
0.35	GO:0032403	protein complex binding

0.63	GO:0097144	BAX complex
0.61	GO:0005757	mitochondrial permeability transition pore complex
0.53	GO:0005741	mitochondrial outer membrane
0.51	GO:0005789	endoplasmic reticulum membrane
0.50	GO:0005635	nuclear envelope
0.50	GO:0005829	cytosol
0.41	GO:0071944	cell periphery
0.37	GO:0070062	extracellular exosome
0.35	GO:0048471	perinuclear region of cytoplasm

0.36

EC:1.3.1.20

GO:0047115

sp|Q07817|B2CL1_HUMAN
Bcl-2-like protein 1
Search

0.97	Anti-apoptotic regulator Bcl-xL

0.74	GO:0042981	regulation of apoptotic process
0.74	GO:0006915	apoptotic process
0.63	GO:0043069	negative regulation of programmed cell death
0.62	GO:0038034	signal transduction in absence of ligand
0.60	GO:0046902	regulation of mitochondrial membrane permeability
0.60	GO:0051881	regulation of mitochondrial membrane potential
0.60	GO:0070997	neuron death
0.60	GO:0010332	response to gamma radiation
0.59	GO:0001541	ovarian follicle development
0.59	GO:0060154	cellular process regulating host cell cycle in response to virus

0.63	GO:0051434	BH3 domain binding
0.54	GO:0046982	protein heterodimerization activity
0.54	GO:0042802	identical protein binding
0.52	GO:0019901	protein kinase binding
0.46	GO:0051721	protein phosphatase 2A binding
0.45	GO:0002020	protease binding
0.44	GO:0016248	channel inhibitor activity
0.43	GO:0031625	ubiquitin protein ligase binding
0.42	GO:0008134	transcription factor binding
0.40	GO:0022803	passive transmembrane transporter activity

0.58	GO:0097136	Bcl-2 family protein complex
0.56	GO:0005741	mitochondrial outer membrane
0.53	GO:0005813	centrosome
0.51	GO:0005783	endoplasmic reticulum
0.51	GO:0005829	cytosol
0.47	GO:0031965	nuclear membrane
0.45	GO:0043209	myelin sheath
0.43	GO:0046930	pore complex
0.42	GO:0070013	intracellular organelle lumen
0.42	GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network

sp|Q07820|MCL1_HUMAN
Induced myeloid leukemia cell differentiation protein Mcl-1
Search

MCL1

0.90	MCL1, BCL2 family apoptosis regulator b

0.79	GO:1903378	positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
0.77	GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand
0.76	GO:2000811	negative regulation of anoikis
0.75	GO:2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
0.73	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage
0.71	GO:0008637	apoptotic mitochondrial changes
0.67	GO:2001020	regulation of response to DNA damage stimulus
0.67	GO:0034097	response to cytokine
0.64	GO:0010507	negative regulation of autophagy
0.51	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway

0.78	GO:0051434	BH3 domain binding
0.66	GO:0046982	protein heterodimerization activity
0.47	GO:0042803	protein homodimerization activity

0.77	GO:0097136	Bcl-2 family protein complex
0.63	GO:0005759	mitochondrial matrix
0.58	GO:0005829	cytosol
0.54	GO:0005634	nucleus
0.48	GO:0005741	mitochondrial outer membrane
0.30	GO:0016021	integral component of membrane

sp|Q07837|SLC31_HUMAN
Neutral and basic amino acid transport protein rBAT
Search

SLC3A1

0.92	Neutral and basic amino acid transport protein rBAT

0.60	GO:0005975	carbohydrate metabolic process
0.38	GO:0006865	amino acid transport
0.35	GO:0072337	modified amino acid transport
0.35	GO:0072348	sulfur compound transport
0.34	GO:1903825	organic acid transmembrane transport
0.34	GO:0098656	anion transmembrane transport
0.34	GO:0006470	protein dephosphorylation
0.33	GO:0006520	cellular amino acid metabolic process
0.32	GO:0006351	transcription, DNA-templated
0.32	GO:2001141	regulation of RNA biosynthetic process

0.38	GO:0046982	protein heterodimerization activity
0.36	GO:0015184	L-cystine transmembrane transporter activity
0.36	GO:0015174	basic amino acid transmembrane transporter activity
0.34	GO:0030145	manganese ion binding
0.34	GO:0004721	phosphoprotein phosphatase activity
0.33	GO:0000287	magnesium ion binding
0.33	GO:0032450	maltose alpha-glucosidase activity
0.33	GO:0004558	alpha-1,4-glucosidase activity
0.33	GO:0103025	alpha-amylase activity (releasing maltohexaose)
0.33	GO:0004556	alpha-amylase activity

0.59	GO:0031526	brush border membrane
0.46	GO:0031966	mitochondrial membrane
0.46	GO:0019866	organelle inner membrane
0.39	GO:0005774	vacuolar membrane
0.37	GO:0005887	integral component of plasma membrane
0.37	GO:0070062	extracellular exosome
0.32	GO:0005634	nucleus

0.34

GO:0004721

sp|Q07864|DPOE1_HUMAN
DNA polymerase epsilon catalytic subunit A
Search

POLE

0.46	DNA polymerase epsilon catalytic subunit A

0.66	GO:0071897	DNA biosynthetic process
0.65	GO:0006260	DNA replication
0.63	GO:0006281	DNA repair
0.62	GO:0090305	nucleic acid phosphodiester bond hydrolysis
0.56	GO:0000082	G1/S transition of mitotic cell cycle
0.47	GO:0022616	DNA strand elongation
0.39	GO:0048568	embryonic organ development
0.38	GO:0016070	RNA metabolic process
0.35	GO:0000723	telomere maintenance
0.34	GO:0019725	cellular homeostasis

0.69	GO:0008408	3'-5' exonuclease activity
0.69	GO:0003887	DNA-directed DNA polymerase activity
0.61	GO:0008270	zinc ion binding
0.54	GO:0003677	DNA binding
0.53	GO:0003682	chromatin binding
0.51	GO:1901265	nucleoside phosphate binding
0.50	GO:0036094	small molecule binding
0.48	GO:0008297	single-stranded DNA exodeoxyribonuclease activity
0.36	GO:0051539	4 iron, 4 sulfur cluster binding
0.34	GO:0005515	protein binding

0.82	GO:0008622	epsilon DNA polymerase complex
0.50	GO:0005654	nucleoplasm
0.43	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

0.69

GO:0003887

sp|Q07866|KLC1_HUMAN
Kinesin light chain 1
Search

KLC1

0.84	Kinesin light chain 1

0.46	GO:0097193	intrinsic apoptotic signaling pathway
0.40	GO:0035617	stress granule disassembly
0.38	GO:0035418	protein localization to synapse
0.38	GO:0008088	axo-dendritic transport
0.36	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II
0.36	GO:0006886	intracellular protein transport
0.35	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
0.34	GO:0016032	viral process

0.74	GO:0003777	microtubule motor activity
0.36	GO:0005515	protein binding
0.32	GO:0046872	metal ion binding

0.80	GO:0005871	kinesin complex
0.42	GO:0030426	growth cone
0.39	GO:0031982	vesicle
0.38	GO:0005874	microtubule
0.38	GO:0030424	axon
0.38	GO:0035253	ciliary rootlet
0.37	GO:0043025	neuronal cell body
0.37	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

sp|Q07869|PPARA_HUMAN
Peroxisome proliferator-activated receptor alpha
Search

PPARA

0.96	Peroxisome proliferator-activated receptor alpha

0.78	GO:0030522	intracellular receptor signaling pathway
0.77	GO:0043401	steroid hormone mediated signaling pathway
0.59	GO:0072369	regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter
0.59	GO:0072363	regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter
0.59	GO:0072366	regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter
0.59	GO:0010887	negative regulation of cholesterol storage
0.58	GO:0010871	negative regulation of receptor biosynthetic process
0.58	GO:0010891	negative regulation of sequestering of triglyceride
0.58	GO:0010745	negative regulation of macrophage derived foam cell differentiation
0.58	GO:1902894	negative regulation of pri-miRNA transcription by RNA polymerase II

0.81	GO:0004879	nuclear receptor activity
0.78	GO:0003707	steroid hormone receptor activity
0.63	GO:0043565	sequence-specific DNA binding
0.61	GO:0008270	zinc ion binding
0.56	GO:0001103	RNA polymerase II repressing transcription factor binding
0.56	GO:0031624	ubiquitin conjugating enzyme binding
0.55	GO:0001078	transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.54	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding
0.54	GO:0001077	transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding
0.52	GO:0001012	RNA polymerase II regulatory region DNA binding

0.60	GO:0005634	nucleus
0.47	GO:0070013	intracellular organelle lumen
0.43	GO:0044446	intracellular organelle part

sp|Q07889|SOS1_HUMAN
Son of sevenless homolog 1
Search

SOS1

0.90	SOS Ras/Rac guanine nucleotide exchange factor 1

0.78	GO:0035023	regulation of Rho protein signal transduction
0.77	GO:0007264	small GTPase mediated signal transduction
0.76	GO:1904693	midbrain morphogenesis
0.74	GO:2000973	regulation of pro-B cell differentiation
0.73	GO:0007296	vitellogenesis
0.73	GO:0061029	eyelid development in camera-type eye
0.73	GO:0003344	pericardium morphogenesis
0.71	GO:0033081	regulation of T cell differentiation in thymus
0.71	GO:0001782	B cell homeostasis
0.71	GO:0003209	cardiac atrium morphogenesis

0.78	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.74	GO:0046982	protein heterodimerization activity
0.54	GO:0003677	DNA binding
0.37	GO:0017124	SH3 domain binding

0.47	GO:0000786	nucleosome
0.43	GO:0005737	cytoplasm
0.42	GO:0005634	nucleus
0.38	GO:0014069	postsynaptic density
0.37	GO:0043025	neuronal cell body
0.34	GO:0005886	plasma membrane

sp|Q07890|SOS2_HUMAN
Son of sevenless homolog 2
Search

SOS2

0.93	SOS Ras/Rho guanine nucleotide exchange factor 2

0.78	GO:0035023	regulation of Rho protein signal transduction
0.77	GO:0007264	small GTPase mediated signal transduction
0.66	GO:0065009	regulation of molecular function
0.59	GO:2000973	regulation of pro-B cell differentiation
0.58	GO:1904693	midbrain morphogenesis
0.58	GO:0033081	regulation of T cell differentiation in thymus
0.57	GO:0001782	B cell homeostasis
0.56	GO:0007296	vitellogenesis
0.56	GO:0061029	eyelid development in camera-type eye
0.56	GO:0003344	pericardium morphogenesis

0.78	GO:0005089	Rho guanyl-nucleotide exchange factor activity
0.74	GO:0046982	protein heterodimerization activity
0.54	GO:0003677	DNA binding

0.45	GO:0005622	intracellular
0.35	GO:0044815	DNA packaging complex
0.35	GO:0032993	protein-DNA complex
0.34	GO:0043228	non-membrane-bounded organelle
0.33	GO:0044422	organelle part
0.33	GO:0043227	membrane-bounded organelle

sp|Q07912|ACK1_HUMAN
Activated CDC42 kinase 1
Search

TNK2

0.88	Tyrosine kinase non-receptor

0.77	GO:0018108	peptidyl-tyrosine phosphorylation
0.58	GO:2000369	regulation of clathrin-dependent endocytosis
0.57	GO:0007165	signal transduction
0.55	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
0.48	GO:0046777	protein autophosphorylation
0.47	GO:0045087	innate immune response
0.47	GO:0016477	cell migration
0.46	GO:0042127	regulation of cell proliferation
0.45	GO:0030154	cell differentiation

0.77	GO:0004713	protein tyrosine kinase activity
0.76	GO:0004712	protein serine/threonine/tyrosine kinase activity
0.57	GO:0005154	epidermal growth factor receptor binding
0.55	GO:0032559	adenyl ribonucleotide binding
0.54	GO:0008144	drug binding
0.54	GO:0035639	purine ribonucleoside triphosphate binding
0.53	GO:0031625	ubiquitin protein ligase binding
0.51	GO:0042802	identical protein binding

0.60	GO:0070436	Grb2-EGFR complex
0.54	GO:0005905	clathrin-coated pit
0.53	GO:0030136	clathrin-coated vesicle
0.48	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane
0.45	GO:0005634	nucleus
0.30	GO:0031224	intrinsic component of membrane

0.77

GO:0004713

sp|Q07954|LRP1_HUMAN
Prolow-density lipoprotein receptor-related protein 1
Search

LRP1

0.59	LDL receptor related protein 1

0.79	GO:1905167	positive regulation of lysosomal protein catabolic process
0.78	GO:0002265	astrocyte activation involved in immune response
0.77	GO:1900223	positive regulation of amyloid-beta clearance
0.77	GO:0097242	amyloid-beta clearance
0.75	GO:0045056	transcytosis
0.74	GO:1904646	cellular response to amyloid-beta
0.73	GO:1903078	positive regulation of protein localization to plasma membrane
0.72	GO:0032092	positive regulation of protein binding
0.71	GO:0045807	positive regulation of endocytosis
0.67	GO:0010942	positive regulation of cell death

0.80	GO:0016964	alpha-2 macroglobulin receptor activity
0.76	GO:0032050	clathrin heavy chain binding
0.76	GO:0034185	apolipoprotein binding
0.70	GO:0005509	calcium ion binding
0.64	GO:0032403	protein complex binding

0.70	GO:0016323	basolateral plasma membrane
0.68	GO:0005769	early endosome
0.67	GO:0043235	receptor complex
0.30	GO:0016021	integral component of membrane

sp|Q07955|SRSF1_HUMAN
Serine/arginine-rich splicing factor 1
Search

SRSF1

0.94	Serine and arginine rich splicing factor 1

0.53	GO:0000395	mRNA 5'-splice site recognition
0.53	GO:0000380	alternative mRNA splicing, via spliceosome
0.52	GO:0060048	cardiac muscle contraction
0.49	GO:0001701	in utero embryonic development
0.39	GO:0097421	liver regeneration
0.38	GO:0033120	positive regulation of RNA splicing
0.38	GO:0048709	oligodendrocyte differentiation
0.38	GO:0051028	mRNA transport
0.35	GO:0006369	termination of RNA polymerase II transcription
0.34	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus

0.59	GO:0003723	RNA binding
0.55	GO:0050733	RS domain binding
0.54	GO:0044547	DNA topoisomerase binding
0.39	GO:0043422	protein kinase B binding

0.52	GO:0035145	exon-exon junction complex
0.52	GO:0016607	nuclear speck
0.50	GO:0071013	catalytic step 2 spliceosome
0.36	GO:0070062	extracellular exosome
0.35	GO:0005737	cytoplasm
0.30	GO:0016020	membrane

sp|Q07960|RHG01_HUMAN
Rho GTPase-activating protein 1
Search

ARHGAP1

0.96	Rho GTPase-activating protein 1

0.62	GO:2001136	negative regulation of endocytic recycling
0.60	GO:0007165	signal transduction
0.60	GO:0098706	ferric iron import across plasma membrane
0.59	GO:0033572	transferrin transport
0.58	GO:0032439	endosome localization
0.53	GO:0043087	regulation of GTPase activity
0.52	GO:0051345	positive regulation of hydrolase activity
0.34	GO:0051056	regulation of small GTPase mediated signal transduction
0.34	GO:0009967	positive regulation of signal transduction

0.55	GO:0045296	cadherin binding
0.55	GO:0017137	Rab GTPase binding
0.53	GO:0005096	GTPase activator activity
0.36	GO:0017124	SH3 domain binding
0.35	GO:0005070	SH3/SH2 adaptor activity
0.32	GO:0032550	purine ribonucleoside binding
0.32	GO:0019001	guanyl nucleotide binding
0.32	GO:0032555	purine ribonucleotide binding
0.32	GO:0035639	purine ribonucleoside triphosphate binding

0.60	GO:0097443	sorting endosome
0.54	GO:0048471	perinuclear region of cytoplasm
0.54	GO:0010008	endosome membrane
0.37	GO:0001726	ruffle
0.36	GO:0070062	extracellular exosome
0.34	GO:0005829	cytosol
0.33	GO:0005886	plasma membrane
0.30	GO:0031224	intrinsic component of membrane

sp|Q07973|CP24A_HUMAN
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial
Search

CYP24A1

0.97	LOW QUALITY PROTEIN: 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial

0.61	GO:0042359	vitamin D metabolic process
0.60	GO:0033280	response to vitamin D
0.58	GO:0001649	osteoblast differentiation
0.53	GO:0055114	oxidation-reduction process
0.40	GO:0042363	fat-soluble vitamin catabolic process
0.39	GO:0006706	steroid catabolic process
0.37	GO:1901616	organic hydroxy compound catabolic process
0.36	GO:0071295	cellular response to vitamin
0.36	GO:1990523	bone regeneration
0.35	GO:0030522	intracellular receptor signaling pathway

0.68	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
0.66	GO:0004497	monooxygenase activity
0.64	GO:0030342	1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity
0.63	GO:0020037	heme binding
0.63	GO:0005506	iron ion binding

0.51	GO:0005654	nucleoplasm
0.46	GO:0005739	mitochondrion
0.43	GO:0005886	plasma membrane
0.35	GO:0031968	organelle outer membrane
0.33	GO:0005829	cytosol
0.30	GO:0031224	intrinsic component of membrane

0.68